diff --git a/.gitattributes b/.gitattributes new file mode 100644 index 00000000..814b1d13 --- /dev/null +++ b/.gitattributes @@ -0,0 +1,3 @@ + +# A fixture that must keep its byte-order mark and CRLF line endings. +test/unit_tests/ecTestGEM/data/kcatSourceFixture.tsv -text diff --git a/.github/CONTRIBUTING.md b/.github/CONTRIBUTING.md index 37458459..58ead2bd 100644 --- a/.github/CONTRIBUTING.md +++ b/.github/CONTRIBUTING.md @@ -6,35 +6,35 @@ You can contribute in 2 main ways: by creating issues, and by sending pull reque ### Reporting issues -[Report an issue](https://github.com/SysBioChalmers/GECKO/issues) if you note any of the following: +[Report an issue](https://github.com/CompMetEng/GECKO/issues) if you note any of the following: * Missing feature you would like GECKO to have. * Bug/weird simulation results. * Lacking documentation. * Any type of feedback. -If you are unsure about the issue, consider asking first in the [GitHub Discussions page](https://github.com/SysBioChalmers/GECKO/discussions). +If you are unsure about the issue, consider asking first in the [GitHub Discussions page](https://github.com/CompMetEng/GECKO/discussions). When creating the issue, please make sure: -* You tested your code (if any) with all of GECKO's [requirements](https://github.com/SysBioChalmers/GECKO). +* You tested your code (if any) with all of GECKO's [requirements](https://github.com/CompMetEng/GECKO). * You did your analysis in the `main` branch of the repository. * You provide any necessary files/links needed for understanding the issue. * You checked that a similar issue does not exist already -Feel free to also comment on any of the [open issues](https://github.com/SysBioChalmers/GECKO/issues). When doing so, please comply with our [code of conduct](https://github.com/SysBioChalmers/GECKO/blob/main/.github/CODE_OF_CONDUCT.md). +Feel free to also comment on any of the [open issues](https://github.com/CompMetEng/GECKO/issues). When doing so, please comply with our [code of conduct](https://github.com/CompMetEng/GECKO/blob/develop/.github/CODE_OF_CONDUCT.md). Finally, if you like GECKO please remember to 'star' our Github page (click on the star at top right corner), that way we also have an idea of who is using GECKO! ### Contributing to GECKO -Do you want to contribute to GECKO with some additions or improvements? Consider starting by raising an issue and assign it to yourself to describe what you want to achieve. This way, we reduce the risk of duplicated efforts and you may also get suggestions on how to best proceed, e.g. there may be half-finished work in some branch that you could start with. Also, feel free to browse our [open issues](https://github.com/SysBioChalmers/GECKO/issues): Anything tagged with "help wanted" is open to whoever wants to implement it! +Do you want to contribute to GECKO with some additions or improvements? Consider starting by raising an issue and assign it to yourself to describe what you want to achieve. This way, we reduce the risk of duplicated efforts and you may also get suggestions on how to best proceed, e.g. there may be half-finished work in some branch that you could start with. Also, feel free to browse our [open issues](https://github.com/CompMetEng/GECKO/issues): Anything tagged with "help wanted" is open to whoever wants to implement it! Here's how to set up GECKO for local development to contribute smaller features or changes that you can implement yourself: -1. First of all, make sure that you have all [requirements](https://github.com/SysBioChalmers/GECKO) for running GECKO. +1. First of all, make sure that you have all [requirements](https://github.com/CompMetEng/GECKO) for running GECKO. -2. [Fork the GECKO repository](https://github.com/SysBioChalmers/GECKO/fork) on GitHub. +2. [Fork the GECKO repository](https://github.com/CompMetEng/GECKO/fork) on GitHub. 3. Clone your fork locally: ``` @@ -63,7 +63,7 @@ Here's how to set up GECKO for local development to contribute smaller features ``` [See below](#semantic-commits) for recommendations on how to name your commits. In case of larger updates, you can of course make several commits on a single contribution. However, if you need to do too many commits, consider if your contribution could be instead split into separate PRs (making it easier for reviewing later). -8. Submit a PR through the GitHub website (https://help.github.com/articles/creating-a-pull-request-from-a-fork/) to the `develop` branch of the original SysBioChalmers repo (not your fork). We recommend ticking the box "Allow edits from maintainers" if you wish for us to be able to contribute directly to your branch (speeding-up the reviewing process). +8. Submit a PR through the GitHub website (https://help.github.com/articles/creating-a-pull-request-from-a-fork/) to the `develop` branch of the original CompMetEng repository (not your fork). We recommend ticking the box "Allow edits from maintainers" if you wish for us to be able to contribute directly to your branch (speeding-up the reviewing process). Note that steps 3, 4, 5 and 7 can be done, if you prefer, with any git client, such as [Github Desktop](https://desktop.github.com/). @@ -95,7 +95,7 @@ Please use concise descriptive commit messages. Ideally, use [semantic commit me * `refactor`: see [code refactoring](https://en.wikipedia.org/wiki/Code_refactoring). * `style`: minor format changes to functions or data. -More examples [here](https://github.com/SysBioChalmers/GECKO/commits/master). A more detailed explanation or comments is encouraged to be left in the commit description. +More examples [here](https://github.com/CompMetEng/GECKO/commits/develop). A more detailed explanation or comments is encouraged to be left in the commit description. ## Development team guidelines @@ -108,13 +108,13 @@ Changes to the source code _may not_ be directly committed to the `main` or `dev * Skip step 2 of the contribution process. * In step 3 of the contribution process, clone directly the original repo: ``` - git clone https://github.com/SysBioChalmers/GECKO.git + git clone https://github.com/CompMetEng/GECKO.git ``` Follow all other steps in the same way. Also, when creating your pull request (or after you have created it): * Choose 1 or more members of the team (ideally with knowledge on the pull request) as reviewers. Note that the person making the pull request and the reviewer _cannot_ be the same person. -* Assign appropriate [labels](https://github.com/SysBioChalmers/GECKO/issues/labels). +* Assign appropriate [labels](https://github.com/CompMetEng/GECKO/issues/labels). ### Reviewing pull requests @@ -124,7 +124,7 @@ Every pull request must be approved by at least one reviewer before it can be me * **Documentation:** The reasoning for each modification should be provided, as documentation or as a comment in the pull request. * **Reproducibility:** If there are any added scripts, make sure that if you run them, they achieve the desired purpose. * **Style:** Ensure that changes to the codebase have a compliant style, and new datasets (if any) are straight-forward to understand. -* When commenting in the review, please comply with our [code of conduct](https://github.com/SysBioChalmers/GECKO/blob/main/.github/CODE_OF_CONDUCT.md). +* When commenting in the review, please comply with our [code of conduct](https://github.com/CompMetEng/GECKO/blob/develop/.github/CODE_OF_CONDUCT.md). * Avoid vague comments and try to be as explicit as possible (e.g.: _"Please include X here"_ instead of _"X could be included here"_). * As much as possible, try to keep the review process in the pull request discussion, and not in separate private emails. @@ -133,8 +133,8 @@ Every pull request must be approved by at least one reviewer before it can be me This section is meant for the administrator of this repo. The main duties of the administrator are: * To keep the repository clean and organized, i.e. avoid redundancy in functions and/or data, and keep coherency in naming of files. -* To help in the reviewing process of external pull requests by assigning reviewers and [labels](https://github.com/SysBioChalmers/GECKO/issues/labels), if applicable. -* To keep [issues](https://github.com/SysBioChalmers/GECKO/issues) with the proper labels, and to close issues once they are fixed in the `main` branch. +* To help in the reviewing process of external pull requests by assigning reviewers and [labels](https://github.com/CompMetEng/GECKO/issues/labels), if applicable. +* To keep [issues](https://github.com/CompMetEng/GECKO/issues) with the proper labels, and to close issues once they are fixed in the `main` branch. * In cases of disagreement between contributors, to decide how to resolve the issue. * To merge open pull requests into `develop` regularly (see [below](#merging-contributions)). * To generate new releases of the model regularly (see [below](#releasing-a-new-version)). @@ -146,7 +146,7 @@ The following points should be considered when merging branches to `develop`: * Make sure the branch gets accepted by at least one developer with writing access. * Wait at least a day before merging, to allow other developers to inspect the pull request. * To simplify the git history, use "Squash and merge" in pull requests to `develop` (but **never** use this option when merging to `main`, see also below). -* As soon as the branch is merged, confirm that `develop` is still possible to merge to `main` (this can be checked [here](https://github.com/SysBioChalmers/GECKO/compare/develop)). If conflicts appear, fix the conflict _locally_ as soon as possible in `develop` and then push it (note, **DO NOT** pull any other changes from `main` to `develop`, just the single file that is creating the conflict). +* As soon as the branch is merged, confirm that `develop` is still possible to merge to `main` (this can be checked [here](https://github.com/CompMetEng/GECKO/compare/develop)). If conflicts appear, fix the conflict _locally_ as soon as possible in `develop` and then push it. Changes of `main` reach `develop` only through the pull request of the last step of [releasing a new version](#releasing-a-new-version). ### Releasing a new version @@ -164,15 +164,28 @@ GECKO follows [semantic versioning](https://semver.org/): - Re-organization of data - Refactoring of code. +`version.txt` and the version in the first sentence of the `README.md` after "About GECKO" are release-only: they exist on `main` and never on `develop`, which is ahead of the last release by an unknown number of changes. A check on every pull request into `develop` rejects `version.txt`. + When releasing, please follow these steps: -1. Create a pull request from `develop` to `main`: +1. Create the branch `release/` from `develop`, with two changes: + - Add `version.txt` containing the version, e.g. `4.0.0b2`. + - In `README.md`, replace "This is the development version of GECKO 4." by "This is GECKO ****." +2. Create a pull request from `release/` to `main`: - Specify the intended version in the title, e.g. `GECKO 3.0.1` - - Indicating all new features/fixes/etc. and referencing every previous pull request included (examples [here](https://github.com/SysBioChalmers/GECKO/releases)). - - If any [issue](https://github.com/SysBioChalmers/GECKO/issues) gets solved in the release, write in the pull request description "Closes #X", where "X" is the issue number. That way the issue will be automatically closed after merge. -2. Wait at least a day for at least one approval. The GitHub Actions must also pass successfully. -3. Merge the pull request from `develop` to `main` with the option "Create a merge commit", **not** "Squash and merge". -4. Edit the `version.txt` in the `main` branch directly [link](https://github.com/SysBioChalmers/GECKO/edit/main/version.txt) to refer to the new version number. Commit the change directly to the `main` branch. -5. Make the [new release](https://github.com/SysBioChalmers/GECKO/releases/new) at GitHub: - - Define a new tag with the version, prefixed by `v`: e.g. `v3.0.1`. - - Copy the description from the corresponding PR from step 1. + - Indicating all new features/fixes/etc. and referencing every previous pull request included (examples [here](https://github.com/CompMetEng/GECKO/releases)). The description is the release text, as GECKO has no changelog file. + - If any [issue](https://github.com/CompMetEng/GECKO/issues) gets solved in the release, write in the pull request description "Closes #X", where "X" is the issue number. That way the issue will be automatically closed after merge. +3. Wait at least a day for at least one approval. The GitHub Actions must also pass successfully. +4. Merge the pull request into `main` with the option "Create a merge commit", **not** "Squash and merge". +5. Make the [new release](https://github.com/CompMetEng/GECKO/releases/new) at GitHub: + - Define a new tag with the version, without prefix: e.g. `4.0.0b2`, as the existing tags. + - Copy the description from the pull request of step 2. +6. Bring `main` back into `develop` through a pull request from a branch cut from `develop`, without the release-only changes: + ``` + git checkout -b sync/main-to-develop- origin/develop + git merge --no-commit --no-ff origin/main + git rm --cached version.txt + git checkout origin/develop -- README.md + git commit -m "chore: merge main into develop after " + ``` + Merge this pull request with "Create a merge commit". `develop` then contains `main`, and the next release pull request shows only the changes since this release. diff --git a/.github/ISSUE_TEMPLATE/bug-detected.md b/.github/ISSUE_TEMPLATE/bug-detected.md index b6e2c265..885d8df0 100644 --- a/.github/ISSUE_TEMPLATE/bug-detected.md +++ b/.github/ISSUE_TEMPLATE/bug-detected.md @@ -29,6 +29,6 @@ is very useful for us to replicate the problem you encountered. --> #### I hereby confirm that: -- [ ] My GECKO installation met [all requirements](https://github.com/SysBioChalmers/GECKO#required-software). +- [ ] My GECKO installation met [all requirements](https://github.com/CompMetEng/GECKO#required-software). - [ ] This bug occurs in the `main` branch of the repository. -- [ ] A similar [issue](https://github.com/SysBioChalmers/GECKO/issues) does not already exist. +- [ ] A similar [issue](https://github.com/CompMetEng/GECKO/issues) does not already exist. diff --git a/.github/ISSUE_TEMPLATE/config.yml b/.github/ISSUE_TEMPLATE/config.yml index 2bd78878..ca68f2a1 100644 --- a/.github/ISSUE_TEMPLATE/config.yml +++ b/.github/ISSUE_TEMPLATE/config.yml @@ -1,5 +1,5 @@ blank_issues_enabled: true contact_links: - name: GitHub Discussions - url: https://github.com/SysBioChalmers/GECKO/discussions + url: https://github.com/CompMetEng/GECKO/discussions about: You may also ask for support (or contribute with answers) at the GitHub Discussions page. diff --git a/.github/ISSUE_TEMPLATE/new-feature.md b/.github/ISSUE_TEMPLATE/new-feature.md index a4b6a904..d489c3bd 100644 --- a/.github/ISSUE_TEMPLATE/new-feature.md +++ b/.github/ISSUE_TEMPLATE/new-feature.md @@ -16,4 +16,4 @@ assignees: '' #### I hereby confirm that: - [ ] The new feature is not already in the `main` branch of the repository. -- [ ] A similar [issue](https://github.com/SysBioChalmers/GECKO/issues) does not already exist. +- [ ] A similar [issue](https://github.com/CompMetEng/GECKO/issues) does not already exist. diff --git a/.github/workflows/branch-hygiene.yml b/.github/workflows/branch-hygiene.yml new file mode 100644 index 00000000..de1563f8 --- /dev/null +++ b/.github/workflows/branch-hygiene.yml @@ -0,0 +1,36 @@ +name: Branch hygiene + +# version.txt is stamped at release time and belongs on main only. develop is +# never "at" a version, it is ahead of the last release by an unknown number of +# changes. .gitignore cannot keep the file off develop: it is consulted only for +# untracked paths, so once the file is tracked on main, a merge of main into +# develop carries it across regardless. This check prevents that. +on: + pull_request: + branches: [develop] + push: + branches: [develop] + +jobs: + no-release-only-files-on-develop: + runs-on: ubuntu-latest + timeout-minutes: 5 + steps: + - name: Checkout + uses: actions/checkout@v5 + + # On a pull_request event this runs against the merge result rather than + # the pull-request branch, so it answers "would develop contain this once + # this is merged?", which also catches a file arriving through a merge + # commit. + - name: No release-only files on develop + run: | + found=$(git ls-files 'version.txt') + if [ -n "$found" ]; then + echo "::error::version.txt is stamped at release time and belongs on main only." + echo "If it arrived here through a merge of main into develop, drop it in the merge commit:" + echo "" + echo " git rm --cached version.txt" + exit 1 + fi + echo "No release-only files tracked on develop." diff --git a/.github/workflows/tests.yml b/.github/workflows/tests.yml index 349922ac..4250acd1 100644 --- a/.github/workflows/tests.yml +++ b/.github/workflows/tests.yml @@ -20,15 +20,13 @@ jobs: - name: Checkout GECKO uses: actions/checkout@v5 - # develop3, not RAVEN's default branch. GECKO 4 is developed against - # RAVEN's develop3 line, and taking the default meant testing against - # main --- which is why the removal of progressbar went unnoticed here - # while breaking every user on develop3. + # RAVEN develop holds RAVEN 3, which GECKO 4 is developed against; RAVEN + # main holds the RAVEN release. - name: Checkout RAVEN uses: actions/checkout@v5 with: - repository: SysBioChalmers/RAVEN - ref: develop3 + repository: CompMetEng/RAVEN + ref: develop path: RAVEN - name: Set up MATLAB diff --git a/.gitignore b/.gitignore index 9a68a6d8..a03cabba 100644 --- a/.gitignore +++ b/.gitignore @@ -17,6 +17,8 @@ geckopy/geckopy/data_files/*.xml *.ppt* # Only allowed .mat file !phylDist.mat +# BRENDA files, downloaded by fetchBrendaAsset +databases/brenda-*/ # Ignore intermediate model files *_stage*.yml diff --git a/GECKO.png b/GECKO.png deleted file mode 100644 index 1f4ebe29..00000000 Binary files a/GECKO.png and /dev/null differ diff --git a/GECKOInstaller.m b/GECKOInstaller.m index 08e50b5f..55f85aff 100644 --- a/GECKOInstaller.m +++ b/GECKOInstaller.m @@ -10,14 +10,14 @@ sourceDir = fileparts(which(mfilename)); paths = GECKOInstaller.GetFilteredSubPaths(sourceDir, GECKOInstaller.FILE_FILTER); - GECKOInstaller.checkRAVENversion('2.9.1'); % Minimum RAVEN version + GECKOInstaller.checkRAVENversion('3.0.0'); % Minimum RAVEN version % Check unique function names if ~exist("checkFunctionUniqueness.m") error(['Cannot find RAVEN Toolbox in the MATLAB path. Make ' ... 'sure you have installed RAVEN in accordance to the ' ... 'following instructions, including running ''checkInstallation()'': ' ... - 'https://github.com/SysBioChalmers/RAVEN/wiki/Installation']) + 'https://raven-docs.readthedocs.io/en/latest/installation/raven.html']) else status=checkFunctionUniqueness(paths); if ~status @@ -65,35 +65,30 @@ function checkRAVENversion(minmVer) wrongVersion = false; try if exist('checkRaven','file') == 2 - [currVer, installType] = checkRaven('versionOnly'); + currVer = checkRaven('versionOnly'); else - [currVer, installType] = checkInstallation('versionOnly'); + currVer = checkInstallation('versionOnly'); end if strcmp(currVer,'develop') printOrange('WARNING: Cannot determine your RAVEN version as it is in a development branch.\n'); else - wrongVersion = GECKOInstaller.isOlderVersion(currVer, minmVer); + % A pre-release suffix of the installed RAVEN (3.0.0b2) is + % ignored: it satisfies the minimum 3.0.0. + wrongVersion = GECKOInstaller.isOlderVersion( ... + GECKOInstaller.releaseOf(currVer), minmVer); end catch warning(['Cannot find RAVEN Toolbox in the MATLAB path, or the version ' ... 'is too old for this GECKO version (RAVEN ' minmVer ' is required). ' ... 'Make sure you have installed RAVEN following the instructions available '... - 'here, '... + 'here, '... 'including running ''checkInstallation()''.']) end if wrongVersion - switch installType - case 0 - installType = 'advanced'; - case 1 - installType = 'easy'; - case 2 - installType = 'medium'; - end error(['Installed RAVEN version is %s, while the minimum is %s. '... 'Upgrade RAVEN by following the instructions available ' ... - 'here. Do not attempt to run GECKO before upgrading.'], ... + 'here. ' ... + 'Do not attempt to run GECKO before upgrading.'], ... currVer,minmVer) end end @@ -107,13 +102,13 @@ function checkRAVENversion(minmVer) fclose('all'); fprintf('GECKO version %s installed',currVer) try - newVer=strtrim(webread('https://raw.githubusercontent.com/SysBioChalmers/GECKO/main/version.txt')); + newVer=strtrim(webread('https://raw.githubusercontent.com/CompMetEng/GECKO/main/version.txt')); if GECKOInstaller.isOlderVersion(currVer, newVer) fprintf(', newer version %s is available',newVer) if ~hasGit fprintf('\nRun git pull in your favourite git client to update GECKO\n'); else - fprintf('\nInstructions on how to upgrade here\n'); + fprintf('\nInstructions on how to upgrade here\n'); end else fprintf('\n'); @@ -144,6 +139,13 @@ function checkRAVENversion(minmVer) end end + function release = releaseOf(ver) + % releaseOf The major.minor.patch part of a version string + % without its pre-release suffix (3.0.0b2 gives 3.0.0). + num = GECKOInstaller.parseVersion(ver); + release = sprintf('%d.%d.%d', num); + end + function [num, isPre] = parseVersion(ver) % parseVersion Leading numbers of major.minor.patch, and % whether the patch number carries a pre-release suffix. diff --git a/README.md b/README.md index 62fdeaa8..4e0cf8a1 100644 --- a/README.md +++ b/README.md @@ -1,21 +1,29 @@ - + + + GECKO + -[![Current release](https://img.shields.io/github/release/SysBioChalmers/GECKO/all.svg)](https://GitHub.com/SysBioChalmers/GECKO/releases/) -[![GitHub Discussions](https://img.shields.io/github/discussions-search?query=repo%3Asysbiochalmers%2Fgecko&label=GitHub%20Discussions)](https://github.com/SysBioChalmers/GECKO/discussions) -[![Zenodo](https://zenodo.org/badge/DOI/10.5281/zenodo.7699818.svg)](https://doi.org/10.5281/zenodo.7699818) -[![MATLAB File Exchange](https://www.mathworks.com/matlabcentral/images/matlab-file-exchange.svg)](https://se.mathworks.com/matlabcentral/fileexchange/125960-gecko-toolbox) +[![Documentation](https://readthedocs.org/projects/gecko-docs/badge/?version=latest)](https://gecko-docs.readthedocs.io/en/latest/) +[![GitHub Discussions](https://img.shields.io/github/discussions-search?query=repo%3ACompMetEng%2FGECKO&label=GitHub%20Discussions)](https://github.com/CompMetEng/GECKO/discussions) +**[Documentation](https://gecko-docs.readthedocs.io/en/latest/)** · [Installation](https://gecko-docs.readthedocs.io/en/latest/installation/) · [Guide](https://gecko-docs.readthedocs.io/en/latest/guide/) · [API reference](https://gecko-docs.readthedocs.io/en/latest/api/) · [Migrate](https://gecko-docs.readthedocs.io/en/latest/migrate.html) · [Citations](https://gecko-docs.readthedocs.io/en/latest/references.html) -## About GECKO 3 +## About GECKO The **GECKO** toolbox enhances a **G**enome-scale model to account for **E**nzyme **C**onstraints, using **K**inetics and **O**mics. The resulting enzyme-constrained model (**ecModel**) can be used to perform simulations where enzyme allocation is either drawn from a total protein pool, or constrained by measured protein levels from proteomics data. -💡 In the [`GECKO/tutorials`](https://github.com/SysBioChalmers/GECKO/tree/main/tutorials) folder there are examples of how GECKO can be applied to GEMs, in either of its _full_ or _light_ forms. Each `protocol.m` contains instructions on how to reconstruct and analyze an ecModel, demonstrating how different fuctions in GECKO can be used. These two scripts complement the [Nature Protocols](https://doi.org/10.1038/s41596-023-00931-7) paper ([**PDF**](https://drive.google.com/file/d/1_AGz6GmQPOyshfUZ6K-L2myzU43rQ6tu/view)). +GECKO is written in MATLAB. Its Python port, [geckopy](https://github.com/CompMetEng/geckopy), reads and writes the same ecModel YAML files, and the two toolboxes are kept in step by a [parity ledger](https://github.com/CompMetEng/raven-gecko-parity). The documentation covers both. -### Significant changes since protocol publication -- GECKO **3.2.0**: all protein usage reactions draw from the protein pool, even if they are constrained by proteomics data. This affects **Step 58** in the protocol, changing behaviour of `constrainEnzConcs` and making `updateProtPool` obsolete, `tutorials/full_ecModel/protocol.m` is updated to reflect this change. See [#357](https://github.com/SysBioChalmers/GECKO/issues/375) for more details. - -_**Note:** Regarding code and model compatibility with earlier GECKO versions, see [Previous versions: GECKO 1 and 2](https://github.com/SysBioChalmers/GECKO/wiki/Previous-versions:-GECKO-1-and-2)_. +This is GECKO **4.0.0b2**. For the changes from GECKO 3, see [GECKO 3 → GECKO 4](https://gecko-docs.readthedocs.io/en/latest/gecko3-to-gecko4.html); for the differences between GECKO and geckopy, see [GECKO vs. geckopy](https://gecko-docs.readthedocs.io/en/latest/gecko-to-geckopy.html). + +## Get started + +1. Install GECKO as described in the [installation instructions](https://gecko-docs.readthedocs.io/en/latest/installation/). +2. Follow [Getting started](https://gecko-docs.readthedocs.io/en/latest/guide/getting-started.html) and [Building an ecModel](https://gecko-docs.readthedocs.io/en/latest/guide/building-ec-model.html) in the guide, or open `tutorials/full_ecModel/protocol.m` or `tutorials/light_ecModel/protocol.m` in MATLAB. Each script reconstructs and analyses an ecModel step by step, in its _full_ or _light_ form ([GECKO light](https://gecko-docs.readthedocs.io/en/latest/guide/gecko-light.html)), and complements the [Nature Protocols](https://doi.org/10.1038/s41596-023-00931-7) paper. + +## Documentation and support + +The installation instructions, the protocol and the API reference for MATLAB and Python are at [gecko-docs](https://gecko-docs.readthedocs.io/en/latest/). Use [GitHub Discussions](https://github.com/CompMetEng/GECKO/discussions) for questions and comments. ## Cite us @@ -23,10 +31,6 @@ If you have used GECKO in your work, please cite: > Chen Y, Gustafsson J, Tafur Rangel A, Anton M, Domenzain I, Kittikunapong C, Li F, Yuan L, Nielsen J & Kerkhoven EJ. Reconstruction, simulation and analysis of enzyme-constrained metabolic models using GECKO Toolbox 3.0. *Nature Protocols* **19**, 629-667 (2024). doi:[10.1038/s41596-023-00931-7](https://doi.org/10.1038/s41596-023-00931-7). -## Documentation -**Installation instructions** and other information is available in the **[Wiki](https://github.com/SysBioChalmers/GECKO/wiki)**. The source code documentation is also available -[online](http://sysbiochalmers.github.io/GECKO/doc/). Use [GitHub Discussions](https://github.com/SysBioChalmers/GECKO/discussions) for support, to ask questions or leave comments. - ## Contributing -Contributions are always welcome! Please read the [contributing guidelines](https://github.com/SysBioChalmers/GECKO/blob/main/.github/CONTRIBUTING.md) to get started. +Contributions are welcome. Read the [contributing guidelines](https://github.com/CompMetEng/GECKO/blob/develop/.github/CONTRIBUTING.md) first. A change to a function that geckopy also has needs the matching change there; the [parity ledger](https://github.com/CompMetEng/raven-gecko-parity) lists the pairs. diff --git a/_config.yml b/_config.yml index 1c6c8f42..5c06be48 100644 --- a/_config.yml +++ b/_config.yml @@ -1,5 +1,5 @@ theme: jekyll-theme-minimal -logo: GECKO.png +logo: img/gecko-logo.png show_downloads: true exclude: [.github, databases, src, test, userData] keep_files: ["doc/"] \ No newline at end of file diff --git a/databases/README.md b/databases/README.md index e4cb7156..9169ef75 100644 --- a/databases/README.md +++ b/databases/README.md @@ -8,17 +8,17 @@ `DLKcatIgnoreMets.tsv` is a table of small metabolites/ions that `writeDLKcatInput` filters out as DLKcat does not predict kcat values for such substrates. This can either be in this folder (and a pull request to the GitHub repository will make this more widely available to other users), or by keeping a copy of this file in the `data` subfolder of the model adapter folder. -### kcat values from BRENDA +### BRENDA -`kcat.tsv` collates kcat values per organism, reaction and substrate, as gathered from the BRENDA database. Both a per-triple maximum (`kcat_max`) and median (`kcat_median`) are recorded; `loadBRENDAdata` currently uses `kcat_max` only. Produced by the `geckopy brenda-refresh` CLI in the [geckopy](https://github.com/SysBioChalmers/geckopy) Python package, which maintains the actively updated BRENDA-parsing tooling for both toolboxes; `mw.tsv` and `sa.tsv` below come from the same tool and share its `#`-prefixed release-version header line. +GECKO does not ship BRENDA data. `fetchBrendaAsset` downloads the files of the [toolbox-assets](https://github.com/CompMetEng/toolbox-assets) release `brenda-2026.1-1` ([BRENDA](https://www.brenda-enzymes.org) 2026.1, CC BY 4.0) on first use into `databases/brenda-2026.1-1`, checked against the manifest checksums. geckopy uses the same release. A project can use its own BRENDA files instead, in `data/brenda`, written by the `geckopy brenda-refresh` CLI of [geckopy](https://github.com/CompMetEng/geckopy). -### Molecular weights +- `kcat.tsv`: kcat values per organism, reaction and substrate. Both a per-triple maximum (`kcat_max`) and median (`kcat_median`) are recorded. Which one is used is set by `params.kcatAggregation` on the model adapter, or per call with `fuzzyKcatMatching(model,'kcatAggregation','median')`; the default is `max`. +- `sa.tsv`: specific activities per organism, reaction and substrate, with a maximum (`sa_max`) and median (`sa_median`); `loadBRENDAdata` uses `sa_max`. +- `mw.tsv`: molecular weights per organism and reaction (without explicitly referring to a protein identifier). +- `measurements.tsv`: one row per wild-type kcat measurement with an EC number: EC number, substrate (name and InChIKey), organism, UniProt accession and sequence id, kcat (1/s; the geometric midpoint of a range), temperature, pH and PubMed id. Values more than four orders of magnitude below their EC class, and clusters of values below 0.01 /s that sit three orders of magnitude under the other values of their EC number, are left out as unit errors. `kcatsFromECTree` reads it (see `loadBrendaMeasurements`). +- `sequences.fasta`, `substrates.tsv` and `kcatCombineParams.tsv`: the sequences and substrates of the measurements, and the parameters of the `combine` stage. -`mw.tsv` is a collation of molecular weights per organism and reaction (without explicitly referring to a protein identifier), as gathered from the BRENDA database. - -### Specific activities from BRENDA - -`sa.tsv` collates specific activities per organism, reaction and substrate, as gathered from the BRENDA database. Like `kcat.tsv`, both a maximum (`sa_max`) and median (`sa_median`) are recorded; `loadBRENDAdata` currently uses `sa_max` only. +Each file starts with a `#` line naming the BRENDA release. ### Taxonomic tree diff --git a/databases/kcat.tsv b/databases/kcat.tsv deleted file mode 100644 index 68923ca2..00000000 --- a/databases/kcat.tsv +++ /dev/null @@ -1,39320 +0,0 @@ -# BRENDA release 2026.1 generated 2026-05-28 - CC BY 4.0 - kcat in 1/s -ec_code substrate organism kcat_max kcat_median n references -1.1.1.1 (2e)-but-2-en-1-ol yokenella sp. 101.0 101.0 1 PMID:24509923 -1.1.1.1 (2e)-but-2-enal yokenella sp. 405.0 405.0 1 PMID:24509923 -1.1.1.1 (r)-1-indanol sulfolobus acidocaldarius 7.1 7.1 1 PMID:20049620 -1.1.1.1 (r)-2-butanol equus caballus 2.0 2.0 1 PMID:1935957 -1.1.1.1 (r)-2-butanol saccharolobus solfataricus 1.0 1.0 1 PMID:19588068 -1.1.1.1 (r)-2-octanol equus caballus 0.053 0.053 1 PMID:1935957 -1.1.1.1 (r)-2-pentanol equus caballus 1.01 1.01 1 PMID:1935957 -1.1.1.1 (r)-2-pentanol saccharolobus solfataricus 1.1 1.1 1 PMID:19588068 -1.1.1.1 (r)-alpha-tetralol sulfolobus acidocaldarius 13.5 13.5 1 PMID:20049620 -1.1.1.1 (s)-(+)-1-indanol thermus thermophilus 61.4 61.4 1 PMID:18456852 -1.1.1.1 (s)-(+)-alpha-tetraol thermus thermophilus 57.0 57.0 1 PMID:18456852 -1.1.1.1 (s)-(-)-1-phenylethanol thermus thermophilus 1.1 1.1 1 PMID:18456852 -1.1.1.1 (s)-1-indanol sulfolobus acidocaldarius 13.7 13.7 1 PMID:20049620 -1.1.1.1 (s)-1-indanol thermus thermophilus 61.4 61.4 1 PMID:18456852 -1.1.1.1 (s)-1-phenylethanol thermus thermophilus 1.1 1.1 1 PMID:18456852 -1.1.1.1 (s)-2-butanol equus caballus 1.0 1.0 1 PMID:1935957 -1.1.1.1 (s)-2-butanol homo sapiens 2.17 2.17 1 PMID:7876099 -1.1.1.1 (s)-2-butanol saccharolobus solfataricus 1.2 1.2 1 PMID:19588068 -1.1.1.1 (s)-2-octanol equus caballus 1.52 1.52 1 PMID:1935957 -1.1.1.1 (s)-2-pentanol equus caballus 0.87 0.87 1 PMID:1935957 -1.1.1.1 (s)-2-pentanol saccharolobus solfataricus 2.6 2.6 1 PMID:19588068 -1.1.1.1 (s)-alpha-tetralol sulfolobus acidocaldarius 2.1 2.1 1 PMID:20049620 -1.1.1.1 (s)-alpha-tetralol thermus thermophilus 57.0 57.0 1 PMID:18456852 -1.1.1.1 1,3-propanediol geobacillus stearothermophilus 0.041 0.041 1 PMID:31006524 -1.1.1.1 1,4-butanediol pyrobaculum calidifontis 1.98 1.98 1 PMID:29022135 -1.1.1.1 1-butanol aeropyrum pernix 0.41 0.41 1 PMID:16233615 -1.1.1.1 1-butanol geobacillus stearothermophilus 0.004 0.004 1 PMID:31006524 -1.1.1.1 1-butanol mesocricetus auratus 7.5 7.5 1 PMID:3178842 -1.1.1.1 1-butanol rattus norvegicus 48.8 24.816499999999998 2 PMID:3816781 -1.1.1.1 1-butanol saccharolobus solfataricus 3.1 3.1 1 PMID:19588068 -1.1.1.1 1-heptanol saccharolobus solfataricus 1.6 1.6 1 PMID:19588068 -1.1.1.1 1-hexanol aeropyrum pernix 0.37 0.37 1 PMID:16233615 -1.1.1.1 1-hexanol mesocricetus auratus 3.03 3.03 1 PMID:3178842 -1.1.1.1 1-hexanol saccharolobus solfataricus 2.0 2.0 1 PMID:19588068 -1.1.1.1 1-indanol sulfolobus acidocaldarius 6.2 6.2 1 PMID:22805786 -1.1.1.1 1-indanol thermus thermophilus 45.7 45.7 1 PMID:18456852 -1.1.1.1 1-indanone thermus thermophilus 8.3 8.3 2 PMID:18456852 -1.1.1.1 1-octanol homo sapiens 2.83 2.83 1 PMID:2936344 -1.1.1.1 1-octanol rattus norvegicus 60.8 2.33 3 PMID:3816781 -1.1.1.1 1-pentanol aeropyrum pernix 0.45 0.45 1 PMID:16233615 -1.1.1.1 1-pentanol homo sapiens 0.183 0.183 1 PMID:2936344 -1.1.1.1 1-pentanol rattus norvegicus 48.8 3.53 3 PMID:3816781 -1.1.1.1 1-pentanol saccharolobus solfataricus 2.5 2.5 1 PMID:19588068 -1.1.1.1 1-phenyl-1,2-propandione thermus thermophilus 17.1 17.1 1 PMID:18456852 -1.1.1.1 1-phenyl-1,2-propanedione sulfolobus acidocaldarius 5.3 4.2 2 PMID:20049620;PMID:22805786 -1.1.1.1 1-phenyl-1,2-propanedione thermus thermophilus 17.1 17.1 1 PMID:18456852 -1.1.1.1 1-phenylethanol thermococcus kodakarensis 35.7 35.7 1 PMID:23354700 -1.1.1.1 1-propanol aeropyrum pernix 0.26 0.26 1 PMID:16233615 -1.1.1.1 1-propanol geobacillus stearothermophilus 0.019 0.019 1 PMID:31006524 -1.1.1.1 1-propanol saccharolobus solfataricus 2.6 2.2 5 PMID:10074357;PMID:11265460;PMID:19588068;PMID:8555238 -1.1.1.1 11-cis-retinal equus caballus 0.021 0.021 1 PMID:9059637 -1.1.1.1 11-cis-retinol equus caballus 0.022 0.022 1 PMID:9059637 -1.1.1.1 12-hydroxydodecanoate coturnix coturnix 1.45 1.45 1 PMID:2789998 -1.1.1.1 12-hydroxydodecanoate homo sapiens 4.0 3.03 3 PMID:6375718;PMID:6397223;PMID:7876099 -1.1.1.1 12-hydroxydodecanoate mesocricetus auratus 2.77 2.3150000000000004 4 PMID:3178842;PMID:8730210 -1.1.1.1 12-hydroxydodecanoate rattus norvegicus 20.0 3.83 3 PMID:3816781 -1.1.1.1 12-hydroxydodecanoic acid homo sapiens 0.333 0.333 1 PMID:2936344 -1.1.1.1 12-hydroxylauric acid methyl ester geobacillus stearothermophilus 27.6 27.6 1 PMID:26329849 -1.1.1.1 12-oxolauric acid methyl ester geobacillus stearothermophilus 308.0 308.0 1 PMID:26329849 -1.1.1.1 13-cis-retinal equus caballus 0.018 0.018 1 PMID:9059637 -1.1.1.1 13-cis-retinol equus caballus 0.018 0.018 1 PMID:9059637 -1.1.1.1 16-hydroxyhexadecanoate homo sapiens 6.17 6.17 1 PMID:6397223 -1.1.1.1 2',3',4',5',6'-pentafluoroacetophenone sulfolobus acidocaldarius 3.2 3.2 1 PMID:22805786 -1.1.1.1 2,2,2-trifluoroacetophenone sulfolobus acidocaldarius 10.0 5.85 2 PMID:20049620;PMID:22805786 -1.1.1.1 2,2,2-trifluoroacetophenone thermus thermophilus 25.5 25.5 2 PMID:18456852 -1.1.1.1 2,2-dichloroacetophenone sulfolobus acidocaldarius 0.65 0.65 1 PMID:22805786 -1.1.1.1 2,3-butanediol pyrococcus furiosus 2.6 0.5365 4 PMID:20632378;PMID:28201792 -1.1.1.1 2,3-butanediol thermococcus kodakarensis 43.8 43.8 1 PMID:23354700 -1.1.1.1 2-butanol aeropyrum pernix 0.48 0.48 1 PMID:16233615 -1.1.1.1 2-butanol geobacillus stearothermophilus 0.094 0.094 1 PMID:31006524 -1.1.1.1 2-butanol mesocricetus auratus 4.75 4.75 1 PMID:3178842 -1.1.1.1 2-butanone equus caballus 0.12 0.12 1 PMID:1935957 -1.1.1.1 2-buten-1-ol rattus norvegicus 213.0 5.83 3 PMID:3816781 -1.1.1.1 2-decanone aeropyrum pernix 0.4 0.4 1 PMID:16233615 -1.1.1.1 2-dehydro-3-deoxy-d-gluconate sphingomonas sp. a1 1.4 1.4 1 PMID:29697194 -1.1.1.1 2-deoxy-d-ribose homo sapiens 2.83 2.83 1 PMID:6397223 -1.1.1.1 2-ethoxyethanol saccharolobus solfataricus 1.6 1.6 1 PMID:19588068 -1.1.1.1 2-heptanone aeropyrum pernix 0.73 0.73 1 PMID:16233615 -1.1.1.1 2-hexanone aeropyrum pernix 1.08 1.08 1 PMID:16233615 -1.1.1.1 2-nonanone aeropyrum pernix 1.0 1.0 1 PMID:16233615 -1.1.1.1 2-octanone aeropyrum pernix 0.74 0.74 1 PMID:16233615 -1.1.1.1 2-pentanol aeropyrum pernix 0.6 0.6 1 PMID:16233615 -1.1.1.1 2-pentanone aeropyrum pernix 0.77 0.77 1 PMID:16233615 -1.1.1.1 2-pentanone equus caballus 0.0713 0.0713 1 PMID:1935957 -1.1.1.1 2-propanol aeropyrum pernix 0.24 0.24 1 PMID:16233615 -1.1.1.1 2-propanol geobacillus stearothermophilus 287.0 287.0 1 PMID:23686507 -1.1.1.1 2-propanol homo sapiens 0.75 0.75 1 PMID:6397223 -1.1.1.1 2-propanol saccharolobus solfataricus 0.45 0.25 3 PMID:11265460;PMID:8555238 -1.1.1.1 3,4-dihydro-retinal homo sapiens 1.22 0.72 2 PMID:15369820 -1.1.1.1 3,4-dihydro-retinol homo sapiens 2.5 1.294 2 PMID:15369820 -1.1.1.1 3-bromobenzyl alcohol saccharolobus solfataricus 2.0 1.6 2 PMID:8555238 -1.1.1.1 3-bromobenzylalcohol saccharolobus solfataricus 1.2 1.2 1 PMID:11265460 -1.1.1.1 3-hydroxy-2-butanone pyrococcus furiosus 0.36 0.28 2 PMID:20632378 -1.1.1.1 3-methoxybenzaldehyde thermus thermophilus 3.1 3.1 1 PMID:18456852 -1.1.1.1 3-methoxybenzyl alcohol saccharolobus solfataricus 16.0 8.7 2 PMID:8555238 -1.1.1.1 3-methoxybenzylalcohol saccharolobus solfataricus 1.4 1.2999999999999998 2 PMID:11265460 -1.1.1.1 3-methyl-1-butanol equus caballus 0.27 0.27 1 PMID:8532667 -1.1.1.1 3-methyl-cyclohexanol saccharolobus solfataricus 7.72 7.72 1 PMID:3115775 -1.1.1.1 3-methylbutan-2-one saccharolobus solfataricus 1.22 1.22 1 PMID:3115775 -1.1.1.1 3-methylcyclohexanone saccharolobus solfataricus 2.17 2.17 1 PMID:3115775 -1.1.1.1 3-methylcyclohexanone sulfolobus acidocaldarius 3.8 3.8 1 PMID:20049620 -1.1.1.1 3-oxo-5beta-androstan-17beta-ol equus caballus 2.05 2.05 1 PMID:20851 -1.1.1.1 3-pentanol equus caballus 2.26 2.26 1 PMID:1935957 -1.1.1.1 3-pentanol saccharolobus solfataricus 1.5 1.5 1 PMID:19588068 -1.1.1.1 3-pentanone equus caballus 0.36 0.36 1 PMID:1935957 -1.1.1.1 3-phenyl-1-propanol homo sapiens 7.5 7.5 1 PMID:6397223 -1.1.1.1 3-pyridylcarbinol homo sapiens 0.683 0.683 1 PMID:836289 -1.1.1.1 4-amino-1-butanol equus caballus 380.0 380.0 1 * -1.1.1.1 4-bromobenzyl alcohol saccharolobus solfataricus 3.5 2.3 2 PMID:8555238 -1.1.1.1 4-bromobenzylalcohol saccharolobus solfataricus 1.1 1.1 1 PMID:11265460 -1.1.1.1 4-carboxybenzaldehyde saccharolobus solfataricus 0.7 0.7 2 PMID:11265460;PMID:8555238 -1.1.1.1 4-chloroacetophenone rhodococcus ruber 432.0 230.0 3 PMID:22584819 -1.1.1.1 4-hydroxy-retinol homo sapiens 34.2 2.83 3 PMID:15369820 -1.1.1.1 4-methoxybenzaldehyde saccharolobus solfataricus 3.3 0.6 3 PMID:10074357;PMID:11265460;PMID:8555238 -1.1.1.1 4-methoxybenzaldehyde thermus thermophilus 3.1 3.1 1 PMID:18456852 -1.1.1.1 4-methoxybenzyl alcohol aeropyrum pernix 0.6 0.6 1 PMID:16233615 -1.1.1.1 4-methoxybenzyl alcohol saccharolobus solfataricus 20.5 2.9 5 PMID:10074357;PMID:19588068;PMID:8555238 -1.1.1.1 4-methoxybenzyl alcohol thermus thermophilus 1.6 1.6 2 PMID:18456852 -1.1.1.1 4-methoxybenzylalcohol saccharolobus solfataricus 1.5 1.5 1 PMID:11265460 -1.1.1.1 4-methoxyphenylacetone aeropyrum pernix 0.071 0.071 1 PMID:16233615 -1.1.1.1 4-methyl-1-pentanol equus caballus 6.7 6.7 1 PMID:8532667 -1.1.1.1 4-nitrobenzaldehyde saccharolobus solfataricus 4.6 4.6 2 PMID:11265460;PMID:8555238 -1.1.1.1 4-oxo-retinal homo sapiens 20.0 7.83 3 PMID:15369820 -1.1.1.1 5beta-pregnan-21-ol-3,20-dione hemisuccinate equus caballus 0.9 0.9 1 PMID:20851 -1.1.1.1 9-cis-retinal equus caballus 0.023 0.023 1 PMID:9059637 -1.1.1.1 9-cis-retinol equus caballus 0.025 0.025 1 PMID:9059637 -1.1.1.1 acetaldehyde citrobacter sp. s-77 2.5 2.5 1 PMID:26216639 -1.1.1.1 acetaldehyde equus caballus 31.8 31.8 1 PMID:20851 -1.1.1.1 acetaldehyde geobacillus stearothermophilus 681.0 681.0 1 PMID:26329849 -1.1.1.1 acetaldehyde geobacillus thermodenitrificans 404.8 404.8 1 PMID:19383697 -1.1.1.1 acetaldehyde kluyveromyces marxianus 283.0 168.0 2 PMID:24885162 -1.1.1.1 acetaldehyde natronomonas pharaonis 5.4 2.85 2 PMID:18189118 -1.1.1.1 acetaldehyde ogataea angusta 3500.0 3500.0 1 PMID:22249723 -1.1.1.1 acetaldehyde parageobacillus thermoglucosidasius 350.0 216.5 2 PMID:24100328 -1.1.1.1 acetaldehyde saccharomyces cerevisiae 313.14 313.14 1 PMID:32967812 -1.1.1.1 acetaldehyde saimiri sciureus 16.7 10.015 2 PMID:7011375 -1.1.1.1 acetoin thermococcus kodakarensis 13.7 13.7 1 PMID:23354700 -1.1.1.1 acetone equus caballus 0.33 0.33 1 PMID:1935957 -1.1.1.1 acetone saccharolobus solfataricus 0.317 0.317 1 PMID:3115775 -1.1.1.1 acetophenone rhodococcus ruber 288.0 259.0 3 PMID:22584819 -1.1.1.1 all-trans retinol mesocricetus auratus 1.9 1.3 3 PMID:8730210 -1.1.1.1 all-trans-retinal equus caballus 2.5 1.261 2 PMID:9059637 -1.1.1.1 all-trans-retinal homo sapiens 1.83 0.55 3 PMID:15369820 -1.1.1.1 all-trans-retinol equus caballus 1.55 1.55 1 PMID:9059637 -1.1.1.1 all-trans-retinol homo sapiens 0.9 0.325 4 PMID:15369820;PMID:7876099 -1.1.1.1 alpha-tetralol thermus thermophilus 48.1 48.1 1 PMID:18456852 -1.1.1.1 alpha-tetralone thermus thermophilus 7.7 7.7 2 PMID:18456852 -1.1.1.1 anisaldehyde saccharolobus solfataricus 0.983 0.983 1 PMID:3115775 -1.1.1.1 benzaldehyde aeropyrum pernix 1.22 1.22 1 PMID:16233615 -1.1.1.1 benzaldehyde equus caballus 29.5 29.5 1 PMID:20851 -1.1.1.1 benzaldehyde saccharolobus solfataricus 11.3 3.5 5 PMID:10074357;PMID:11265460;PMID:19588068;PMID:8555238 -1.1.1.1 benzaldehyde yokenella sp. 360.0 360.0 1 PMID:24509923 -1.1.1.1 benzil sulfolobus acidocaldarius 1.6 1.6 1 PMID:22805786 -1.1.1.1 benzyl alcohol aeropyrum pernix 1.02 1.02 1 PMID:16233615 -1.1.1.1 benzyl alcohol coturnix coturnix 2.52 2.52 1 PMID:2789998 -1.1.1.1 benzyl alcohol equus caballus 0.78 0.78 1 PMID:20851 -1.1.1.1 benzyl alcohol geobacillus stearothermophilus 24.9 24.9 1 PMID:23525111 -1.1.1.1 benzyl alcohol homo sapiens 9.17 6.92 2 PMID:6342669;PMID:6397223 -1.1.1.1 benzyl alcohol mesocricetus auratus 1.37 1.37 1 PMID:3178842 -1.1.1.1 benzyl alcohol moraxella sp. 6.9 6.9 1 PMID:23525111 -1.1.1.1 benzyl alcohol rattus norvegicus 89.7 45.35 2 PMID:3816781 -1.1.1.1 benzyl alcohol saccharolobus solfataricus 14.5 3.6 5 PMID:10074357;PMID:19588068;PMID:3115775;PMID:8555238 -1.1.1.1 benzyl alcohol yokenella sp. 93.3 93.3 1 PMID:24509923 -1.1.1.1 benzylalcohol saccharolobus solfataricus 1.4 1.4 1 PMID:11265460 -1.1.1.1 butan-1-ol coturnix coturnix 7.22 7.22 1 PMID:2789998 -1.1.1.1 butan-1-ol mycobacterium sp. 2.0 2.0 1 PMID:25082080 -1.1.1.1 butan-1-ol saccharolobus solfataricus 1.97 1.97 1 PMID:3115775 -1.1.1.1 butan-2-ol equus caballus 11.9 11.9 1 PMID:8532667 -1.1.1.1 butan-2-ol saccharolobus solfataricus 3.55 3.55 1 PMID:3115775 -1.1.1.1 butan-2-one saccharolobus solfataricus 1.93 1.93 1 PMID:3115775 -1.1.1.1 butanal mycobacterium sp. 102.0 102.0 1 PMID:25082080 -1.1.1.1 butanal saccharomyces cerevisiae 1.99 1.99 1 PMID:28265724 -1.1.1.1 butanol alligator mississippiensis 1.1 1.1 1 PMID:8365416 -1.1.1.1 butanol equus caballus 118.0 118.0 1 PMID:8532667 -1.1.1.1 butanol homo sapiens 34.8 17.75 2 PMID:7876099;PMID:836289 -1.1.1.1 butanol saimiri sciureus 0.45 0.35 3 PMID:7011375 -1.1.1.1 butyl alcohol equus caballus 0.94 0.94 1 PMID:20851 -1.1.1.1 butyraldehyde equus caballus 35.4 35.4 1 PMID:20851 -1.1.1.1 butyraldehyde geobacillus stearothermophilus 931.0 931.0 1 PMID:26329849 -1.1.1.1 butyraldehyde saccharolobus solfataricus 19.7 19.7 1 PMID:19588068 -1.1.1.1 capronaldehyde rhodococcus ruber 576.0 410.0 3 PMID:22584819 -1.1.1.1 cinnamaldehyde geobacillus stearothermophilus 55.0 55.0 1 PMID:23686507 -1.1.1.1 cinnamyl alcohol equus caballus 133.0 133.0 1 PMID:8532667 -1.1.1.1 cinnamyl alcohol geobacillus stearothermophilus 43.0 43.0 1 PMID:23686507 -1.1.1.1 cis-decahydro-1-naphthol sulfolobus acidocaldarius 0.98 0.98 1 PMID:20049620 -1.1.1.1 cycloheptanol sulfolobus acidocaldarius 7.0 5.7 2 PMID:20049620;PMID:22805786 -1.1.1.1 cyclohexanol aeropyrum pernix 0.52 0.52 1 PMID:16233615 -1.1.1.1 cyclohexanol alligator mississippiensis 0.167 0.167 1 PMID:8365416 -1.1.1.1 cyclohexanol coturnix coturnix 3.55 2.15 2 PMID:2789998 -1.1.1.1 cyclohexanol homo sapiens 0.583 0.583 1 PMID:6397223 -1.1.1.1 cyclohexanol mesocricetus auratus 8.5 2.215 4 PMID:3178842;PMID:8730210 -1.1.1.1 cyclohexanol rattus norvegicus 1.75 1.5 3 PMID:3816781 -1.1.1.1 cyclohexanol saccharolobus solfataricus 1.2 1.2 5 PMID:10074357;PMID:11265460;PMID:19588068;PMID:8555238 -1.1.1.1 cyclohexanone aeropyrum pernix 1.27 1.27 1 PMID:16233615 -1.1.1.1 cyclohexanone equus caballus 5.9 5.9 1 PMID:20851 -1.1.1.1 cyclopentanone saccharolobus solfataricus 1.02 1.02 1 PMID:3115775 -1.1.1.1 d-allonate sphingomonas sp. a1 0.18 0.18 1 PMID:29697194 -1.1.1.1 d-altronate sphingomonas sp. a1 0.19 0.19 1 PMID:29697194 -1.1.1.1 d-arabitol sphingomonas sp. a1 0.0019 0.0019 1 PMID:29697194 -1.1.1.1 d-gluconate sphingomonas sp. a1 0.98 0.98 1 PMID:29697194 -1.1.1.1 d-mannonate sphingomonas sp. a1 0.53 0.53 1 PMID:29697194 -1.1.1.1 d-ribonate sphingomonas sp. a1 0.0052 0.0052 1 PMID:29697194 -1.1.1.1 d-sorbitol sphingomonas sp. a1 0.0052 0.0052 1 PMID:29697194 -1.1.1.1 d-talonate sphingomonas sp. a1 0.021 0.021 1 PMID:29697194 -1.1.1.1 d-xylonate sphingomonas sp. a1 0.032 0.032 1 PMID:29697194 -1.1.1.1 ethanol aeropyrum pernix 0.23 0.23 1 PMID:16233615 -1.1.1.1 ethanol alligator mississippiensis 0.467 0.467 1 PMID:8365416 -1.1.1.1 ethanol arabidopsis thaliana 31.5 31.5 1 PMID:30252897 -1.1.1.1 ethanol bacillus subtilis 2.47 2.125 2 PMID:28320283 -1.1.1.1 ethanol citrobacter sp. s-77 3.2 3.2 1 PMID:26216639 -1.1.1.1 ethanol coturnix coturnix 6.63 5.775 2 PMID:2789998 -1.1.1.1 ethanol equus caballus 308.0 123.0 3 PMID:20851;PMID:8532667 -1.1.1.1 ethanol flavobacterium frigidimaris 474.9 135.15 6 PMID:17072683 -1.1.1.1 ethanol geobacillus stearothermophilus 305.0 152.5095 2 PMID:26329849;PMID:31006524 -1.1.1.1 ethanol geobacillus thermodenitrificans 638.7 638.7 1 PMID:19383697 -1.1.1.1 ethanol homo sapiens 30.7 3.83 9 PMID:11964133;PMID:236461;PMID:6342669;PMID:6397223;PMID:7876099;PMID:836289 -1.1.1.1 ethanol kluyveromyces marxianus 158.0 87.5 4 PMID:24885162 -1.1.1.1 ethanol mesocricetus auratus 9.58 5.6899999999999995 4 PMID:3178842;PMID:8730210 -1.1.1.1 ethanol mus musculus 215.0 22.86 4 PMID:15096205 -1.1.1.1 ethanol natronomonas pharaonis 8.2 4.3 2 PMID:18189118 -1.1.1.1 ethanol ogataea angusta 3000.0 3000.0 1 PMID:22249723 -1.1.1.1 ethanol picrophilus oshimae 0.00086 0.00086 1 PMID:17989975 -1.1.1.1 ethanol rattus norvegicus 62.7 31.85 2 PMID:3816781 -1.1.1.1 ethanol saccharolobus solfataricus 3.1 0.85 5 PMID:11265460;PMID:19588068;PMID:3115775;PMID:8555238 -1.1.1.1 ethanol saccharomyces cerevisiae 895.4 432.3 5 PMID:17072683;PMID:19034537 -1.1.1.1 ethanol saimiri sciureus 0.567 0.42500000000000004 4 PMID:7011375 -1.1.1.1 ethyl 3-methyl-2-oxobutyrate sulfolobus acidocaldarius 26.0 26.0 1 PMID:22805786 -1.1.1.1 ethyl benzoylformate sulfolobus acidocaldarius 2.35 2.125 2 PMID:20049620;PMID:22805786 -1.1.1.1 ethyl benzoylformate thermus thermophilus 50.1 50.1 1 PMID:18456852 -1.1.1.1 ethyl oxo(phenyl)acetate thermus thermophilus 50.1 50.1 1 PMID:18456852 -1.1.1.1 ethyl pyruvate carboxydothermus hydrogenoformans 3.97 3.97 1 PMID:23160740 -1.1.1.1 ethylene glycol homo sapiens 0.75 0.75 1 PMID:6397223 -1.1.1.1 ethylene glycol pseudomonas aeruginosa 4.5 4.5 1 PMID:15152088 -1.1.1.1 formaldehyde saccharomyces cerevisiae 1.28 1.28 1 PMID:28265724 -1.1.1.1 furfural saccharomyces cerevisiae 36.9 19.24 2 PMID:28265724;PMID:32967812 -1.1.1.1 glutaraldehyde pyrobaculum calidifontis 93.13 93.13 1 PMID:29022135 -1.1.1.1 glycolaldehyde saccharomyces cerevisiae 18.65 17.044999999999998 2 PMID:28265724;PMID:32967812 -1.1.1.1 hexaldehyde equus caballus 56.6 56.6 1 PMID:20851 -1.1.1.1 hexanol alligator mississippiensis 0.167 0.167 1 PMID:8365416 -1.1.1.1 hexanol equus caballus 29.6 29.6 1 PMID:8532667 -1.1.1.1 hexanol homo sapiens 19.5 19.5 1 PMID:7876099 -1.1.1.1 hexanol mus musculus 86.5 17.315 4 PMID:15096205 -1.1.1.1 hexyl alcohol equus caballus 0.99 0.99 1 PMID:20851 -1.1.1.1 isatin sulfolobus acidocaldarius 22.0 22.0 1 PMID:20049620 -1.1.1.1 iso-propanol geobacillus stearothermophilus 0.076 0.076 1 PMID:31006524 -1.1.1.1 isoborneol sulfolobus acidocaldarius 16.6 16.6 1 PMID:22805786 -1.1.1.1 isobutyraldehyde saccharolobus solfataricus 29.0 29.0 1 PMID:19588068 -1.1.1.1 isopropanol equus caballus 0.58 0.58 1 PMID:1935957 -1.1.1.1 methanol alligator mississippiensis 0.05 0.05 1 PMID:8365416 -1.1.1.1 methanol geobacillus stearothermophilus 0.013 0.013 1 PMID:31006524 -1.1.1.1 methanol homo sapiens 0.102 0.102 1 PMID:236461 -1.1.1.1 methanol saccharolobus solfataricus 3.1 3.1 1 PMID:3115775 -1.1.1.1 methanol saimiri sciureus 0.217 0.167 2 PMID:7011375 -1.1.1.1 methyl benzoylformate sulfolobus acidocaldarius 6.2 6.2 1 PMID:20049620 -1.1.1.1 methyl o-chlorobenzoylformate sulfolobus acidocaldarius 9.2 9.2 1 PMID:20049620 -1.1.1.1 methyl oxo(phenyl)acetate thermus thermophilus 38.1 38.1 1 PMID:18456852 -1.1.1.1 methylbenzoylformate thermus thermophilus 38.1 38.1 1 PMID:18456852 -1.1.1.1 methylcrotonyl alcohol mesocricetus auratus 8.58 3.0 3 PMID:8730210 -1.1.1.1 n-butanol geobacillus stearothermophilus 195.0 195.0 1 PMID:26329849 -1.1.1.1 n-butanol mesocricetus auratus 7.18 3.33 3 PMID:8730210 -1.1.1.1 n-hexanol mesocricetus auratus 4.08 2.8 3 PMID:8730210 -1.1.1.1 nad+ aeropyrum pernix 0.4 0.4 1 PMID:16233615 -1.1.1.1 nad+ coturnix coturnix 6.18 5.425 2 PMID:2789998 -1.1.1.1 nad+ geobacillus stearothermophilus 34.2 33.0 3 PMID:23686507;PMID:25314615;PMID:26329849 -1.1.1.1 nad+ geobacillus thermodenitrificans 443.1 443.1 1 PMID:19383697 -1.1.1.1 nad+ homo sapiens 0.717 0.717 1 PMID:836289 -1.1.1.1 nad+ mesocricetus auratus 7.75 7.75 1 PMID:3178842 -1.1.1.1 nad+ mycobacterium sp. 1.0 1.0 1 PMID:25082080 -1.1.1.1 nad+ pyrococcus furiosus 2.6 1.8 2 PMID:20632378;PMID:28201792 -1.1.1.1 nad+ saccharolobus solfataricus 18.5 3.4 5 PMID:10074357;PMID:11265460;PMID:19588068;PMID:8555238 -1.1.1.1 nad+ sulfolobus acidocaldarius 19.3 11.5 2 PMID:20049620;PMID:22805786 -1.1.1.1 nad+ thermococcus kodakarensis 30.8 20.6 2 PMID:23354700 -1.1.1.1 nad+ thermus thermophilus 0.84 0.84 2 PMID:18456852 -1.1.1.1 nadh aeropyrum pernix 0.41 0.41 1 PMID:16233615 -1.1.1.1 nadh coturnix coturnix 8.88 8.88 1 PMID:2789998 -1.1.1.1 nadh geobacillus stearothermophilus 326.0 184.5 2 PMID:23686507;PMID:26329849 -1.1.1.1 nadh geobacillus thermodenitrificans 1645.7 1645.7 1 PMID:19383697 -1.1.1.1 nadh mycobacterium sp. 153.0 153.0 1 PMID:25082080 -1.1.1.1 nadh pyrococcus furiosus 0.36 0.36 1 PMID:20632378 -1.1.1.1 nadh saccharolobus solfataricus 10.3 4.5 5 PMID:10074357;PMID:11265460;PMID:19588068;PMID:8555238 -1.1.1.1 nadh sulfolobus acidocaldarius 26.2 17.1 2 PMID:20049620;PMID:22805786 -1.1.1.1 nadh thermococcus kodakarensis 17.3 16.45 2 PMID:23354700 -1.1.1.1 nadh thermus thermophilus 52.4 52.4 2 PMID:18456852 -1.1.1.1 nadp+ geobacillus thermodenitrificans 43.9 43.9 1 PMID:19383697 -1.1.1.1 nadp+ pyrococcus furiosus 0.073 0.0515 2 PMID:20632378;PMID:28201792 -1.1.1.1 nadp+ thermococcus kodakarensis 30.0 20.25 2 PMID:23354700 -1.1.1.1 nadp+ yokenella sp. 194.0 194.0 1 PMID:24509923 -1.1.1.1 nadph pyrococcus furiosus 0.2 0.2 1 PMID:20632378 -1.1.1.1 nadph yokenella sp. 433.0 433.0 1 PMID:24509923 -1.1.1.1 octan-1-ol coturnix coturnix 1.85 1.85 1 PMID:2789998 -1.1.1.1 octanal coturnix coturnix 17.0 17.0 1 PMID:2789998 -1.1.1.1 octanal homo sapiens 3.33 3.33 1 PMID:6375718 -1.1.1.1 octanol alligator mississippiensis 0.15 0.15 1 PMID:8365416 -1.1.1.1 octanol homo sapiens 8.33 4.33 5 PMID:11964133;PMID:6342669;PMID:6375718;PMID:6397223 -1.1.1.1 octanol scyliorhinus canicula 3.17 3.17 1 PMID:21329683 -1.1.1.1 p-nitrophenyl octanoate equus caballus 0.24 0.24 1 PMID:7041828 -1.1.1.1 pentan-1-ol coturnix coturnix 2.92 2.92 1 PMID:2789998 -1.1.1.1 pentan-3-ol saccharolobus solfataricus 2.92 2.92 1 PMID:3115775 -1.1.1.1 pentan2-ol saccharolobus solfataricus 3.82 3.82 1 PMID:3115775 -1.1.1.1 pentanol equus caballus 56.2 56.2 1 PMID:8532667 -1.1.1.1 pentanol homo sapiens 16.0 4.3335 4 PMID:6375718;PMID:6397223;PMID:7876099;PMID:836289 -1.1.1.1 pentanol saimiri sciureus 0.333 0.308 2 PMID:7011375 -1.1.1.1 phenylacetaldehyde rhodococcus ruber 303.0 264.0 3 PMID:22584819 -1.1.1.1 propan-1-ol saccharolobus solfataricus 4.03 4.03 1 PMID:3115775 -1.1.1.1 propan-2-ol equus caballus 53.1 53.1 1 PMID:8532667 -1.1.1.1 propan-2-ol saccharolobus solfataricus 6.92 6.92 1 PMID:3115775 -1.1.1.1 propanal saccharomyces cerevisiae 0.73 0.73 1 PMID:28265724 -1.1.1.1 propanol homo sapiens 17.2 17.2 1 PMID:7876099 -1.1.1.1 propionaldehyde equus caballus 41.9 41.9 1 PMID:20851 -1.1.1.1 propyl alcohol equus caballus 1.17 1.17 1 PMID:20851 -1.1.1.1 retinol homo sapiens 0.11 0.0985 2 PMID:11964133 -1.1.1.1 tert-butanol geobacillus stearothermophilus 0.026 0.026 1 PMID:31006524 -1.1.1.1 tert-butyl acetoacetate aeropyrum pernix 0.072 0.072 1 PMID:16233615 -1.1.1.1 tetralin-1-ol sulfolobus acidocaldarius 9.6 9.6 1 PMID:22805786 -1.1.1.1 trans-cinnamaldehyde saccharolobus solfataricus 2.1 2.1 1 PMID:19588068 -1.1.1.1 tryptophol homo sapiens 1.83 1.83 1 PMID:6397223 -1.1.1.1 valeraldehyde rhodococcus ruber 528.0 432.0 3 PMID:22584819 -1.1.1.1 vanillyl alcohol homo sapiens 8.67 4.5685 2 PMID:6375718;PMID:6397223 -1.1.1.10 acetoin cavia porcellus 6.9 6.9 1 PMID:11882650 -1.1.1.10 acetoin homo sapiens 0.65 0.65 1 PMID:11882650 -1.1.1.10 acetoin mesocricetus auratus 6.9 6.9 1 PMID:11882650 -1.1.1.10 acetoin mus musculus 3.0 3.0 1 PMID:11882650 -1.1.1.10 acetoin rattus norvegicus 6.9 6.9 1 PMID:11882650 -1.1.1.10 d-erythrose caenorhabditis elegans 1.8 1.8 1 PMID:21477590 -1.1.1.10 d-erythrose cavia porcellus 8.0 8.0 1 PMID:11882650 -1.1.1.10 d-erythrose homo sapiens 0.43 0.43 1 PMID:11882650 -1.1.1.10 d-erythrose mesocricetus auratus 23.0 23.0 1 PMID:11882650 -1.1.1.10 d-erythrose mus musculus 18.0 18.0 1 PMID:11882650 -1.1.1.10 d-erythrose rattus norvegicus 18.0 18.0 1 PMID:11882650 -1.1.1.10 d-ribulose cavia porcellus 7.8 7.8 1 PMID:11882650 -1.1.1.10 d-ribulose homo sapiens 0.52 0.52 1 PMID:11882650 -1.1.1.10 d-ribulose mesocricetus auratus 31.0 31.0 1 PMID:11882650 -1.1.1.10 d-ribulose mus musculus 26.0 26.0 1 PMID:11882650 -1.1.1.10 d-ribulose neurospora crassa 119.0 119.0 1 PMID:17261518 -1.1.1.10 d-ribulose rattus norvegicus 19.0 19.0 1 PMID:11882650 -1.1.1.10 d-ribulose trichoderma reesei 8.24 8.24 1 PMID:23506391 -1.1.1.10 d-sorbitol trichoderma reesei 1.8 1.8 1 PMID:23506391 -1.1.1.10 d-threitol cavia porcellus 15.0 15.0 1 PMID:11882650 -1.1.1.10 d-threitol homo sapiens 0.48 0.48 1 PMID:11882650 -1.1.1.10 d-threitol mesocricetus auratus 16.0 16.0 1 PMID:11882650 -1.1.1.10 d-threitol mus musculus 16.0 16.0 1 PMID:11882650 -1.1.1.10 d-threitol rattus norvegicus 12.0 12.0 1 PMID:11882650 -1.1.1.10 d-threose caenorhabditis elegans 2.32 2.32 1 PMID:21477590 -1.1.1.10 d-threose cavia porcellus 32.0 32.0 1 PMID:11882650 -1.1.1.10 d-threose homo sapiens 0.82 0.82 1 PMID:11882650 -1.1.1.10 d-threose mesocricetus auratus 31.0 31.0 1 PMID:11882650 -1.1.1.10 d-threose mus musculus 23.0 23.0 1 PMID:11882650 -1.1.1.10 d-threose rattus norvegicus 8.0 8.0 1 PMID:11882650 -1.1.1.10 d-xylulose caenorhabditis elegans 1.22 1.22 1 PMID:21477590 -1.1.1.10 d-xylulose cavia porcellus 19.0 19.0 1 PMID:11882650 -1.1.1.10 d-xylulose homo sapiens 0.1 0.1 1 PMID:11882650 -1.1.1.10 d-xylulose mesocricetus auratus 6.9 6.9 1 PMID:11882650 -1.1.1.10 d-xylulose mus musculus 7.4 7.4 1 PMID:11882650 -1.1.1.10 d-xylulose rattus norvegicus 18.0 18.0 1 PMID:11882650 -1.1.1.10 diacetyl cavia porcellus 24.0 24.0 1 PMID:11882650 -1.1.1.10 diacetyl homo sapiens 1.6 1.585 2 PMID:11882650;PMID:15103634 -1.1.1.10 diacetyl mesocricetus auratus 30.0 30.0 1 PMID:11882650 -1.1.1.10 diacetyl mus musculus 41.0 41.0 1 PMID:11882650 -1.1.1.10 diacetyl rattus norvegicus 25.0 25.0 1 PMID:11882650 -1.1.1.10 dihydroxyacetone cavia porcellus 3.8 3.8 1 PMID:11882650 -1.1.1.10 dihydroxyacetone homo sapiens 0.23 0.23 1 PMID:11882650 -1.1.1.10 dihydroxyacetone mesocricetus auratus 8.7 8.7 1 PMID:11882650 -1.1.1.10 dihydroxyacetone mus musculus 3.3 3.3 1 PMID:11882650 -1.1.1.10 dihydroxyacetone rattus norvegicus 5.1 5.1 1 PMID:11882650 -1.1.1.10 dl-glyceraldehyde cavia porcellus 20.0 20.0 1 PMID:11882650 -1.1.1.10 dl-glyceraldehyde homo sapiens 0.52 0.52 1 PMID:11882650 -1.1.1.10 dl-glyceraldehyde mesocricetus auratus 22.0 22.0 1 PMID:11882650 -1.1.1.10 dl-glyceraldehyde mus musculus 24.0 24.0 1 PMID:11882650 -1.1.1.10 dl-glyceraldehyde rattus norvegicus 21.0 21.0 1 PMID:11882650 -1.1.1.10 l-erythrulose caenorhabditis elegans 3.32 3.32 1 PMID:21477590 -1.1.1.10 l-erythrulose cavia porcellus 24.0 24.0 1 PMID:11882650 -1.1.1.10 l-erythrulose homo sapiens 0.6 0.6 1 PMID:11882650 -1.1.1.10 l-erythrulose mesocricetus auratus 25.0 25.0 1 PMID:11882650 -1.1.1.10 l-erythrulose mus musculus 23.0 23.0 1 PMID:11882650 -1.1.1.10 l-erythrulose rattus norvegicus 25.0 25.0 1 PMID:11882650 -1.1.1.10 l-ribulose caenorhabditis elegans 0.49 0.49 1 PMID:21477590 -1.1.1.10 l-threose cavia porcellus 27.0 27.0 1 PMID:11882650 -1.1.1.10 l-threose homo sapiens 0.52 0.52 1 PMID:11882650 -1.1.1.10 l-threose mesocricetus auratus 23.0 23.0 1 PMID:11882650 -1.1.1.10 l-threose mus musculus 16.0 16.0 1 PMID:11882650 -1.1.1.10 l-threose rattus norvegicus 16.0 16.0 1 PMID:11882650 -1.1.1.10 l-xylulose caenorhabditis elegans 4.98 4.98 1 PMID:21477590 -1.1.1.10 l-xylulose cavia porcellus 37.0 37.0 1 PMID:11882650 -1.1.1.10 l-xylulose homo sapiens 0.65 0.65 1 PMID:11882650 -1.1.1.10 l-xylulose mesocricetus auratus 6.0 6.0 1 PMID:11882650 -1.1.1.10 l-xylulose mus musculus 37.0 37.0 1 PMID:11882650 -1.1.1.10 l-xylulose rattus norvegicus 39.0 39.0 1 PMID:11882650 -1.1.1.10 l-xylulose trichoderma reesei 11.4 11.4 1 PMID:23506391 -1.1.1.10 nad+ homo sapiens 1.5 1.5 1 PMID:11882650 -1.1.1.10 nad+ mesocricetus auratus 44.0 44.0 1 PMID:11882650 -1.1.1.10 nad+ mus musculus 55.0 55.0 1 PMID:11882650 -1.1.1.10 nad+ rattus norvegicus 41.0 41.0 1 PMID:11882650 -1.1.1.10 nadh cavia porcellus 76.0 76.0 1 PMID:11882650 -1.1.1.10 nadh homo sapiens 3.8 3.8 1 PMID:11882650 -1.1.1.10 nadh mesocricetus auratus 8.0 8.0 1 PMID:11882650 -1.1.1.10 nadh mus musculus 41.0 41.0 1 PMID:11882650 -1.1.1.10 nadh rattus norvegicus 23.0 23.0 1 PMID:11882650 -1.1.1.10 nadp+ cavia porcellus 23.0 23.0 1 PMID:11882650 -1.1.1.10 nadp+ homo sapiens 0.65 0.65 1 PMID:11882650 -1.1.1.10 nadp+ mesocricetus auratus 26.0 26.0 1 PMID:11882650 -1.1.1.10 nadp+ mus musculus 15.0 15.0 1 PMID:11882650 -1.1.1.10 nadp+ rattus norvegicus 10.0 9.75 2 PMID:11882650;PMID:12604240 -1.1.1.10 nadph cavia porcellus 26.0 26.0 1 PMID:11882650 -1.1.1.10 nadph homo sapiens 1.5 1.5 1 PMID:11882650 -1.1.1.10 nadph mesocricetus auratus 27.0 27.0 1 PMID:11882650 -1.1.1.10 nadph mus musculus 34.0 34.0 1 PMID:11882650 -1.1.1.10 nadph rattus norvegicus 25.0 25.0 2 PMID:11882650;PMID:12604240 -1.1.1.10 nadph trichoderma reesei 7.75 7.75 1 PMID:23506391 -1.1.1.10 xylitol cavia porcellus 20.0 20.0 1 PMID:11882650 -1.1.1.10 xylitol homo sapiens 0.6 0.6 1 PMID:11882650 -1.1.1.10 xylitol mesocricetus auratus 8.0 8.0 1 PMID:11882650 -1.1.1.10 xylitol mus musculus 17.0 17.0 1 PMID:11882650 -1.1.1.10 xylitol neurospora crassa 5.6 5.6 1 PMID:17261518 -1.1.1.10 xylitol rattus norvegicus 10.0 10.0 1 PMID:11882650 -1.1.1.10 xylitol trichoderma reesei 1.0 1.0 1 PMID:23506391 -1.1.1.100 3-oxododecanoyl-[acyl-carrier protein] xanthomonas campestris pv. campestris 40.9 40.9 1 PMID:29739899 -1.1.1.100 3-oxooctanoyl-coa mycolicibacterium smegmatis 0.095 0.095 1 PMID:29717709 -1.1.1.100 acetoacetyl-coa cupriavidus necator 102.0 102.0 1 PMID:23913421 -1.1.1.100 acetoacetyl-coa mycobacterium tuberculosis 7.0 7.0 1 PMID:17059223 -1.1.1.100 acetoacetyl-coa mycolicibacterium smegmatis 0.019 0.019 1 PMID:29717709 -1.1.1.100 acetoacetyl-coa plasmodium falciparum 265.0 259.0 3 PMID:12646215;PMID:16225460;PMID:16934037 -1.1.1.100 acetoacetyl-coa saccharomyces cerevisiae 117.5 117.5 1 PMID:23300157 -1.1.1.100 acetoacetyl-coa streptococcus pneumoniae 11.0 11.0 1 PMID:16342966 -1.1.1.100 ethyl acetoacetate escherichia coli 0.3 0.3 1 PMID:18201766 -1.1.1.100 nadph cupriavidus necator 102.0 102.0 1 PMID:23913421 -1.1.1.100 nadph escherichia coli 0.59 0.59 1 PMID:18201766 -1.1.1.100 nadph mycobacterium tuberculosis 7.0 7.0 1 PMID:17059223 -1.1.1.100 nadph plasmodium falciparum 344.7 254.5 6 PMID:16225460;PMID:16934037;PMID:17879351 -1.1.1.100 nadph saccharomyces cerevisiae 117.5 117.5 1 PMID:23300157 -1.1.1.100 nadph streptococcus pneumoniae 11.0 11.0 1 PMID:16342966 -1.1.1.101 nadph cavia porcellus 100.0 100.0 1 PMID:2335525 -1.1.1.102 3-dehydrosphinganine candida albicans 1.07 1.07 1 PMID:16431155 -1.1.1.103 l-serine thermoplasma volcanium 0.01 0.01 1 PMID:31457655 -1.1.1.103 l-threonine cupriavidus necator 50.0 46.9 2 PMID:21073854;PMID:24558034 -1.1.1.103 l-threonine escherichia coli k-12 135.0 135.0 1 PMID:6780553 -1.1.1.103 l-threonine mus musculus 47.3 47.3 1 PMID:26492815 -1.1.1.103 l-threonine pyrococcus horikoshii 551.7 11.0 3 PMID:16233775;PMID:17188300 -1.1.1.103 l-threonine sus scrofa 23.3 23.3 1 PMID:3536927 -1.1.1.103 l-threonine thermoplasma volcanium 1.7 1.7 1 PMID:31457655 -1.1.1.103 l-threonine uncultured archaeon 48.8 48.8 1 PMID:28992410 -1.1.1.103 nad+ cupriavidus necator 38.0 38.0 1 PMID:21073854 -1.1.1.103 nad+ pyrococcus horikoshii 551.7 9.1 4 PMID:16233775;PMID:17188300;PMID:18390572 -1.1.1.105 all-trans-retinal kangiella koreensis 0.028 0.028 1 PMID:25481533 -1.1.1.105 all-trans-retinol homo sapiens 0.02 0.02 1 PMID:16787387 -1.1.1.107 d-arabinose microbacterium luteolum 175.0 175.0 1 PMID:15226311 -1.1.1.107 l-fucose microbacterium luteolum 125.0 125.0 1 PMID:15226311 -1.1.1.107 l-xylose microbacterium luteolum 214.0 214.0 1 PMID:15226311 -1.1.1.107 nad+ mesorhizobium loti 136.0 136.0 2 PMID:16824480 -1.1.1.107 pyridoxal mesorhizobium loti 149.0 149.0 2 PMID:16824480 -1.1.1.107 pyridoxal microbacterium luteolum 59.2 59.2 1 PMID:15226311 -1.1.1.108 carnitine rhizobium sp. 11.77 11.77 1 PMID:23794271 -1.1.1.108 carnitine xanthomonas translucens 1.97 1.6244999999999998 2 PMID:23794271;PMID:24101242 -1.1.1.11 d-arabinitol gluconobacter oxydans 876.0 876.0 1 PMID:19629658 -1.1.1.11 d-arabitol gluconobacter oxydans 876.0 876.0 1 PMID:19629658 -1.1.1.11 d-mannitol gluconobacter oxydans 35.3 35.3 2 PMID:19629658 -1.1.1.11 d-sorbitol gluconobacter oxydans 19.7 19.7 2 PMID:19629658 -1.1.1.11 glycerol gluconobacter oxydans 16.3 16.3 2 PMID:19629658 -1.1.1.11 ribitol gluconobacter oxydans 13.4 13.4 2 PMID:19629658 -1.1.1.11 xylitol gluconobacter oxydans 177.2 177.2 2 PMID:19629658 -1.1.1.118 d-glucose synthetic construct 64.9 64.9 1 * -1.1.1.118 nad+ synthetic construct 69.7 69.7 1 * -1.1.1.118 nadp+ synthetic construct 101.9 101.9 1 * -1.1.1.119 d-glucose haloferax mediterranei 0.5 0.26 3 PMID:17289028 -1.1.1.119 d-glucose sulfurisphaera tokodaii 10.1 5.1049999999999995 2 PMID:24742629 -1.1.1.119 nadp+ sulfurisphaera tokodaii 10.1 5.1049999999999995 2 PMID:24742629 -1.1.1.12 adonitol neurospora crassa 18.0 18.0 1 PMID:17938906 -1.1.1.12 d-sorbitol aspergillus niger 809.0 411.24 2 PMID:19674460 -1.1.1.12 d-sorbitol meyerozyma caribbica 8.28 8.28 1 PMID:27506274 -1.1.1.12 d-sorbitol rasamsonia emersonii 3.7 3.7 1 PMID:20111899 -1.1.1.12 l-arabinitol aspergillus niger 14.4 11.425 2 PMID:19674460;PMID:20414651 -1.1.1.12 l-arabinitol neurospora crassa 20.2 20.2 1 PMID:17938906 -1.1.1.12 l-arabinitol penicillium chrysogenum 18.1 18.1 1 PMID:20414651 -1.1.1.12 l-arabinitol rasamsonia emersonii 5.3 5.3 1 PMID:20111899 -1.1.1.12 l-arabinitol trichoderma reesei 70.0 22.65 4 PMID:20414651;PMID:24342239 -1.1.1.12 l-arabitol aspergillus niger 863.0 863.0 1 PMID:19674460 -1.1.1.12 l-arabitol meyerozyma caribbica 3.35 3.35 1 PMID:27506274 -1.1.1.12 nad+ aspergillus niger 8.23 8.23 1 PMID:20414651 -1.1.1.12 nad+ meyerozyma caribbica 18.5 18.5 1 PMID:27506274 -1.1.1.12 nad+ neurospora crassa 20.1 15.465 2 PMID:17938906;PMID:20655316 -1.1.1.12 nad+ penicillium chrysogenum 17.3 17.3 1 PMID:20414651 -1.1.1.12 nad+ rasamsonia emersonii 4.7 4.7 1 PMID:20111899 -1.1.1.12 nad+ trichoderma reesei 7.26 7.26 1 PMID:20414651 -1.1.1.12 nadp+ meyerozyma caribbica 3.27 3.27 1 PMID:27506274 -1.1.1.12 ribitol meyerozyma caribbica 4.48 4.48 1 PMID:27506274 -1.1.1.12 xylitol aspergillus niger 1180.0 599.835 2 PMID:19674460 -1.1.1.12 xylitol meyerozyma caribbica 18.0 18.0 1 PMID:27506274 -1.1.1.12 xylitol neurospora crassa 15.0 15.0 1 PMID:17938906 -1.1.1.12 xylitol rasamsonia emersonii 3.25 3.25 1 PMID:20111899 -1.1.1.120 d-galactose rhizobium leguminosarum bv. trifolii 69.9 54.010000000000005 2 PMID:25236800 -1.1.1.121 (r)-indanol thermus thermophilus hb8 0.167 0.167 1 PMID:18926808 -1.1.1.121 (r)-tetralol thermus thermophilus hb8 0.075 0.075 1 PMID:18926808 -1.1.1.121 (s)-indanol thermus thermophilus hb8 138.7 138.7 1 PMID:18926808 -1.1.1.121 (s)-tetralol thermus thermophilus hb8 161.7 161.7 1 PMID:18926808 -1.1.1.121 1-acenaphthenol thermus thermophilus hb8 433.3 433.3 1 PMID:18926808 -1.1.1.121 2-cyclohexen-1-ol thermus thermophilus hb8 3.5 3.5 1 PMID:18926808 -1.1.1.121 2-deoxy-d-galactose thermus thermophilus hb8 12.8 12.8 1 PMID:18926808 -1.1.1.121 2-deoxy-d-glucose thermus thermophilus hb8 6.93 6.93 1 PMID:18926808 -1.1.1.121 4-chromanol thermus thermophilus hb8 40.3 40.3 1 PMID:18926808 -1.1.1.121 6-deoxy-d-glucose thermus thermophilus hb8 6.35 6.35 1 PMID:18926808 -1.1.1.121 alpha-tetralone thermus thermophilus hb8 3.9 3.9 1 PMID:18926808 -1.1.1.121 cellobiose thermus thermophilus hb8 5.767 5.767 1 PMID:18926808 -1.1.1.121 cis-benzene dihydrodiol thermus thermophilus hb8 7.383 7.383 1 PMID:18926808 -1.1.1.121 d-fucose thermus thermophilus hb8 8.73 8.73 1 PMID:18926808 -1.1.1.121 d-galactosamine thermus thermophilus hb8 0.3117 0.3117 1 PMID:18926808 -1.1.1.121 d-galactose thermus thermophilus hb8 8.25 8.25 1 PMID:18926808 -1.1.1.121 d-glucosamine thermus thermophilus hb8 0.6217 0.6217 1 PMID:18926808 -1.1.1.121 d-glucose thermus thermophilus hb8 3.85 3.85 1 PMID:18926808 -1.1.1.121 d-talose thermus thermophilus hb8 3.017 3.017 1 PMID:18926808 -1.1.1.121 d-xylose thermus thermophilus hb8 0.423 0.423 1 PMID:18926808 -1.1.1.121 isatin thermus thermophilus hb8 981.7 981.7 1 PMID:18926808 -1.1.1.121 l-arabinose thermus thermophilus hb8 4.55 4.55 1 PMID:18926808 -1.1.1.121 l-fucose thermus thermophilus hb8 0.1067 0.1067 1 PMID:18926808 -1.1.1.121 lactose thermus thermophilus hb8 9.23 9.23 1 PMID:18926808 -1.1.1.121 phenyl-1,2-propanedione thermus thermophilus hb8 16.83 16.83 1 PMID:18926808 -1.1.1.123 5-dehydro-d-fructose clostridium pasteurianum 29.3 29.3 1 PMID:33616697 -1.1.1.127 nadh pectobacterium carotovorum subsp. carotovorum 0.024 0.024 1 PMID:27028675 -1.1.1.127 nadph pectobacterium carotovorum subsp. carotovorum 0.021 0.021 1 PMID:27028675 -1.1.1.133 nadh salmonella enterica 25.0 25.0 1 PMID:10455186 -1.1.1.133 nadph salmonella enterica 29.0 29.0 1 PMID:10455186 -1.1.1.136 nad+ escherichia coli 1.41 1.41 1 PMID:22730467 -1.1.1.136 nad+ salmonella enterica subsp. enterica serovar typhi 15.5 15.5 1 PMID:16800641 -1.1.1.136 udp-n-acetyl-d-glucosamine escherichia coli 0.97 0.97 1 PMID:22730467 -1.1.1.136 udp-n-acetyl-d-glucosamine salmonella enterica subsp. enterica serovar typhi 15.5 15.5 1 PMID:16800641 -1.1.1.14 3-deoxy-d-sorbitol ovis aries 441.0 441.0 1 PMID:14965227 -1.1.1.14 3-fluoro-d-sorbitol ovis aries 350.0 350.0 1 PMID:14965227 -1.1.1.14 4-deoxy-d-sorbitol ovis aries 129.0 129.0 1 PMID:14965227 -1.1.1.14 4-fluoro-d-sorbitol ovis aries 354.0 354.0 1 PMID:14965227 -1.1.1.14 6-deoxy-d-sorbitol ovis aries 274.0 274.0 1 PMID:14965227 -1.1.1.14 6-fluoro-d-sorbitol ovis aries 559.0 559.0 1 PMID:14965227 -1.1.1.14 d-sorbitol [candida] sp. ha 167 161.0 161.0 1 PMID:17343568 -1.1.1.14 d-sorbitol ovis aries 506.0 257.0 2 PMID:14965227;PMID:17343568 -1.1.1.14 d-sorbitol rattus norvegicus 0.71 0.71 1 PMID:17952367 -1.1.1.14 d-xylitol rattus norvegicus 0.63 0.63 1 PMID:17952367 -1.1.1.14 nad+ deinococcus geothermalis 2.7 1.61 3 PMID:22883556 -1.1.1.14 nadp+ deinococcus geothermalis 1.42 1.42 1 PMID:22883556 -1.1.1.140 d-fructose 6-phosphate erwinia amylovora 0.56 0.56 1 PMID:29605571 -1.1.1.140 d-sorbitol 6-phosphate erwinia amylovora 5.6 5.6 1 PMID:29605571 -1.1.1.141 (5z,13e)-(15s)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate homo sapiens 50.0 50.0 1 PMID:15581601 -1.1.1.141 nad+ homo sapiens 47.0 47.0 1 PMID:15581601 -1.1.1.141 prostaglandin e2 homo sapiens 14.1 11.1 7 PMID:21072165 -1.1.1.145 (s)-1-indanol homo sapiens 0.18 0.18 1 PMID:18571493 -1.1.1.145 (s)-1-tetralol homo sapiens 0.25 0.25 1 PMID:18571493 -1.1.1.145 (s)-phenyl-1-butanol homo sapiens 0.075 0.075 1 PMID:18571493 -1.1.1.145 1,4-naphthoquinone homo sapiens 0.88 0.88 1 PMID:18571493 -1.1.1.145 1-phenylisatin homo sapiens 41.7 41.7 1 PMID:18571493 -1.1.1.145 16alpha-hydroxy-dehydroepiandrosterone homo sapiens 0.15 0.12 2 PMID:20420909 -1.1.1.145 16beta-hydroxy-dehydroepiandrosterone homo sapiens 0.14 0.09000000000000001 2 PMID:20420909 -1.1.1.145 2,3-heptanedione homo sapiens 40.2 40.2 1 PMID:18571493 -1.1.1.145 2,3-hexanedione homo sapiens 16.3 16.3 1 PMID:18571493 -1.1.1.145 2,3-pentanedione homo sapiens 26.7 26.7 1 PMID:18571493 -1.1.1.145 4,4'-dimethylbenzil homo sapiens 3.7 3.7 1 PMID:18571493 -1.1.1.145 4-benzoylpyridine homo sapiens 2.0 2.0 1 PMID:18571493 -1.1.1.145 4-hexanoylpyridine homo sapiens 33.3 33.3 1 PMID:18571493 -1.1.1.145 4-nitrobenzaldehyde homo sapiens 16.7 16.7 1 PMID:18571493 -1.1.1.145 5alpha-androstane-3,17-dione homo sapiens 0.097 0.097 1 PMID:18571493 -1.1.1.145 5alpha-dihydrotestosterone homo sapiens 0.095 0.095 1 PMID:18571493 -1.1.1.145 5beta-androstan-17beta-ol-3-one homo sapiens 0.083 0.083 1 PMID:18571493 -1.1.1.145 5beta-androstan-3beta-ol-17-one homo sapiens 0.017 0.017 1 PMID:18571493 -1.1.1.145 5beta-androstane-3,17-dione homo sapiens 0.077 0.077 1 PMID:18571493 -1.1.1.145 5beta-androstane-3beta,17beta-diol homo sapiens 0.017 0.017 1 PMID:18571493 -1.1.1.145 5beta-pregnan-20alpha-ol-3-one homo sapiens 0.07 0.07 1 PMID:18571493 -1.1.1.145 5beta-pregnan-3beta-ol-20-one homo sapiens 0.041 0.041 1 PMID:18571493 -1.1.1.145 5beta-pregnane-3,20-dione homo sapiens 0.063 0.063 1 PMID:18571493 -1.1.1.145 5beta-pregnane-3beta,20alpha-diol homo sapiens 0.014 0.014 1 PMID:18571493 -1.1.1.145 6-tert-butyl-2,3-epoxy-5-cyclohexene-1,4-dione homo sapiens 2.0 2.0 1 PMID:18571493 -1.1.1.145 9,10-phenanthrenequinone homo sapiens 11.8 11.8 1 PMID:18571493 -1.1.1.145 all-trans-retinal homo sapiens 0.05 0.05 1 PMID:18571493 -1.1.1.145 allopregnanolone bos taurus 0.0233 0.0233 1 PMID:10704908 -1.1.1.145 androstenediol bos taurus 0.0333 0.0333 1 PMID:10704908 -1.1.1.145 benzil homo sapiens 31.7 31.7 1 PMID:18571493 -1.1.1.145 dehydroepiandrosterone bos taurus 0.0333 0.0333 1 PMID:10704908 -1.1.1.145 dehydroepiandrosterone bufo gargarizans 0.64 0.64 1 PMID:30170058 -1.1.1.145 dehydroepiandrosterone homo sapiens 0.145 0.057499999999999996 16 PMID:12205101;PMID:15291757;PMID:15797861;PMID:17624763;PMID:18955108;PMID:20420909;PMID:20736065;PMID:29031687 -1.1.1.145 dehydroepiandrosterone mycobacterium tuberculosis 11.6 11.6 1 PMID:17630785 -1.1.1.145 dehydrolithocholic acid homo sapiens 0.043 0.043 1 PMID:18571493 -1.1.1.145 dehydrotomatidine solanum lycopersicum 2769.17 2769.17 1 PMID:30892648 -1.1.1.145 diacetyl homo sapiens 28.3 28.3 1 PMID:18571493 -1.1.1.145 dimethyl-2-oxo-glutarate homo sapiens 33.3 33.3 1 PMID:18571493 -1.1.1.145 hexanophenone homo sapiens 2.7 2.7 1 PMID:18571493 -1.1.1.145 isatin homo sapiens 31.7 31.7 1 PMID:18571493 -1.1.1.145 menadione homo sapiens 0.65 0.65 1 PMID:18571493 -1.1.1.145 n-butyrophenone homo sapiens 0.85 0.85 1 PMID:18571493 -1.1.1.145 nad+ homo sapiens 0.12 0.07 13 PMID:12205101;PMID:15291757;PMID:15797861;PMID:17624763;PMID:18955108;PMID:20420909;PMID:29031687 -1.1.1.145 nadh homo sapiens 1.65 1.2 2 PMID:20420909 -1.1.1.145 pregnenolone bos taurus 0.04 0.04 1 PMID:10704908 -1.1.1.145 pregnenolone bufo gargarizans 2.8 2.8 1 PMID:30170058 -1.1.1.145 pregnenolone mycobacterium tuberculosis 1.48 1.48 1 PMID:17630785 -1.1.1.145 pregnenolone solanum lycopersicum 1145.21 1145.21 1 PMID:30892648 -1.1.1.145 pyridine-4-aldehyde homo sapiens 4.7 4.7 1 PMID:18571493 -1.1.1.145 valerophenone homo sapiens 2.0 2.0 1 PMID:18571493 -1.1.1.146 11beta,21-dihydroxypregn-4-en-3,20-dione rattus sp. 0.000228 0.00015815000000000002 2 PMID:2082184 -1.1.1.146 21-hydroxy-pregn-4-en-3,11,20-trione rattus sp. 0.000183 0.000148 2 PMID:2082184 -1.1.1.146 cortisol cavia porcellus 0.04 0.04 1 PMID:12397058 -1.1.1.146 cortisol homo sapiens 0.19 0.078 3 PMID:12397058;PMID:15513927 -1.1.1.146 cortisone cavia porcellus 0.3 0.3 1 PMID:12397058 -1.1.1.146 cortisone homo sapiens 0.4 0.4 1 PMID:12397058 -1.1.1.149 (s)-1-indanol oryctolagus cuniculus 0.2 0.2 1 PMID:23995665 -1.1.1.149 (s)-1-tetralol oryctolagus cuniculus 0.217 0.217 1 PMID:23995665 -1.1.1.149 17alpha-hydroxyprogesterone rattus norvegicus 0.178 0.178 1 PMID:10417353 -1.1.1.149 17beta-estradiol oryctolagus cuniculus 0.011 0.011 1 PMID:23995665 -1.1.1.149 2-tert-butyl-1,4-benzoquinone oryctolagus cuniculus 0.183 0.183 1 PMID:23995665 -1.1.1.149 20alpha-hydroxy-5alpha-pregnan-3-one rattus norvegicus 0.785 0.785 1 PMID:10417353 -1.1.1.149 20alpha-hydroxyprogesterone oryctolagus cuniculus 0.048 0.048 1 PMID:23995665 -1.1.1.149 20alpha-hydroxyprogesterone rattus norvegicus 1.17 0.5575 4 PMID:10417353;PMID:10500147 -1.1.1.149 3-deoxyglucosone oryctolagus cuniculus 0.183 0.183 1 PMID:23995665 -1.1.1.149 3alpha-hydroxy-5-alpha-pregnan-20-one rattus norvegicus 0.208 0.208 1 PMID:10417353 -1.1.1.149 4-androstene-3,17-dione oryctolagus cuniculus 0.043 0.043 1 PMID:23995665 -1.1.1.149 4-chromanol oryctolagus cuniculus 0.068 0.068 1 PMID:23995665 -1.1.1.149 4-hydroxy-2-nonenal oryctolagus cuniculus 0.009 0.009 1 PMID:23995665 -1.1.1.149 4-nitroacetophenone oryctolagus cuniculus 0.112 0.112 1 PMID:23995665 -1.1.1.149 4-nitrobenzaldehyde rattus norvegicus 5.91 5.91 1 PMID:10417353 -1.1.1.149 4-oxo-2-hexenal oryctolagus cuniculus 0.0115 0.0115 1 PMID:23995665 -1.1.1.149 4-oxo-2-nonenal oryctolagus cuniculus 0.112 0.112 1 PMID:23995665 -1.1.1.149 4-pregnen-3alpha-ol-20-one oryctolagus cuniculus 0.032 0.032 1 PMID:23995665 -1.1.1.149 5-androstene-3beta,17beta-diol oryctolagus cuniculus 0.1 0.1 1 PMID:23995665 -1.1.1.149 5alpha-androstan-3alpha,17beta-diol oryctolagus cuniculus 0.27 0.27 1 PMID:23995665 -1.1.1.149 5alpha-androstan-3alpha-ol-17-one oryctolagus cuniculus 0.085 0.085 1 PMID:23995665 -1.1.1.149 5alpha-androstan-3beta,17beta-diol oryctolagus cuniculus 0.032 0.032 1 PMID:23995665 -1.1.1.149 5alpha-androstan-3beta-ol-17-one oryctolagus cuniculus 0.083 0.083 1 PMID:23995665 -1.1.1.149 5alpha-dihydrotestosterone oryctolagus cuniculus 0.047 0.036000000000000004 2 PMID:23995665 -1.1.1.149 5alpha-pregnan-20alpha-ol-3-one oryctolagus cuniculus 0.158 0.1175 2 PMID:23995665 -1.1.1.149 5alpha-pregnan-3,20-dione oryctolagus cuniculus 0.018 0.018 1 PMID:23995665 -1.1.1.149 5alpha-pregnan-3alpha,20alpha-diol oryctolagus cuniculus 0.025 0.025 1 PMID:23995665 -1.1.1.149 5alpha-pregnan-3alpha,21-diol-20-one oryctolagus cuniculus 0.018 0.018 1 PMID:23995665 -1.1.1.149 5alpha-pregnan-3alpha-ol-20-one oryctolagus cuniculus 0.032 0.032 1 PMID:23995665 -1.1.1.149 5beta-androstan-17beta-ol-3-one oryctolagus cuniculus 0.153 0.153 1 PMID:23995665 -1.1.1.149 5beta-androstan-3alpha,17beta-diol oryctolagus cuniculus 0.25 0.25 1 PMID:23995665 -1.1.1.149 5beta-androstan-3alpha-ol-17-one oryctolagus cuniculus 0.067 0.067 1 PMID:23995665 -1.1.1.149 5beta-androstan-3beta,17beta-diol oryctolagus cuniculus 0.033 0.033 1 PMID:23995665 -1.1.1.149 5beta-androstan-3beta-ol-17-one oryctolagus cuniculus 0.045 0.045 1 PMID:23995665 -1.1.1.149 5beta-pregnan-20alpha-ol-3-one oryctolagus cuniculus 0.153 0.153 1 PMID:23995665 -1.1.1.149 5beta-pregnan-3,20-dione oryctolagus cuniculus 0.028 0.028 1 PMID:23995665 -1.1.1.149 5beta-pregnan-3alpha,20alpha-diol oryctolagus cuniculus 0.283 0.283 1 PMID:23995665 -1.1.1.149 5beta-pregnan-3alpha,21-diol-20-one oryctolagus cuniculus 0.017 0.017 1 PMID:23995665 -1.1.1.149 5beta-pregnan-3alpha-ol-20-one oryctolagus cuniculus 0.03 0.03 1 PMID:23995665 -1.1.1.149 6-tert-butyl-2,3-epoxy-5-cyclohexen-1,4-dione oryctolagus cuniculus 0.167 0.167 1 PMID:23995665 -1.1.1.149 7alpha-hydroxy-dehydroepiandrosterone oryctolagus cuniculus 0.043 0.043 1 PMID:23995665 -1.1.1.149 9,10-phenanthrenequinone rattus norvegicus 7.7 7.7 1 PMID:10417353 -1.1.1.149 acetoin oryctolagus cuniculus 0.097 0.097 1 PMID:23995665 -1.1.1.149 acrolein oryctolagus cuniculus 0.035 0.035 1 PMID:23995665 -1.1.1.149 all-trans-retinal oryctolagus cuniculus 0.0085 0.0085 1 PMID:23995665 -1.1.1.149 alpha-tetralone oryctolagus cuniculus 0.053 0.053 1 PMID:23995665 -1.1.1.149 befunolol oryctolagus cuniculus 0.117 0.117 1 PMID:23995665 -1.1.1.149 beta-ionol oryctolagus cuniculus 0.233 0.233 1 PMID:23995665 -1.1.1.149 cortisol bifidobacterium adolescentis 11.1 11.1 1 PMID:31209107 -1.1.1.149 d,l-glyceraldehyde rattus norvegicus 0.215 0.215 1 PMID:10417353 -1.1.1.149 dehydroepiandrosterone oryctolagus cuniculus 0.155 0.155 1 PMID:23995665 -1.1.1.149 dehydroepiandrosterone 3-sulfate oryctolagus cuniculus 0.08 0.08 1 PMID:23995665 -1.1.1.149 diacetyl oryctolagus cuniculus 0.158 0.158 1 PMID:23995665 -1.1.1.149 estrone oryctolagus cuniculus 0.017 0.017 1 PMID:23995665 -1.1.1.149 estrone 3-sulfate oryctolagus cuniculus 0.098 0.098 1 PMID:23995665 -1.1.1.149 geraniol oryctolagus cuniculus 0.033 0.033 1 PMID:23995665 -1.1.1.149 hexanal oryctolagus cuniculus 0.043 0.043 1 PMID:23995665 -1.1.1.149 isatin oryctolagus cuniculus 0.137 0.137 1 PMID:23995665 -1.1.1.149 isocaproaldehyde oryctolagus cuniculus 0.023 0.023 1 PMID:23995665 -1.1.1.149 ketotifen oryctolagus cuniculus 0.02 0.02 1 PMID:23995665 -1.1.1.149 menadione oryctolagus cuniculus 0.125 0.125 1 PMID:23995665 -1.1.1.149 methylglyoxal oryctolagus cuniculus 0.12 0.12 1 PMID:23995665 -1.1.1.149 nadp+ rattus norvegicus 1.52 1.52 1 PMID:10417353 -1.1.1.149 nadph rattus norvegicus 1.43 1.43 1 PMID:10417353 -1.1.1.149 nonanal oryctolagus cuniculus 0.032 0.032 1 PMID:23995665 -1.1.1.149 progesterone oryctolagus cuniculus 0.027 0.027 1 PMID:23995665 -1.1.1.149 progesterone rattus norvegicus 1.65 1.65 1 PMID:10417353 -1.1.1.149 pyridine 3-aldehyde oryctolagus cuniculus 0.132 0.132 1 PMID:23995665 -1.1.1.149 testosterone oryctolagus cuniculus 0.057 0.057 1 PMID:23995665 -1.1.1.149 trans-2-hexenal oryctolagus cuniculus 0.025 0.025 1 PMID:23995665 -1.1.1.149 trans-2-nonenal oryctolagus cuniculus 0.02 0.02 1 PMID:23995665 -1.1.1.149 trans-benzene dihydrodiol oryctolagus cuniculus 0.108 0.108 1 PMID:23995665 -1.1.1.153 1,2-naphthoquinone homo sapiens 0.627 0.627 1 PMID:23640889 -1.1.1.153 1,4-naphthoquinone homo sapiens 0.45 0.45 1 PMID:23640889 -1.1.1.153 2,3-dimethoxynaphthalene-1,4-dione homo sapiens 1.43 1.43 1 PMID:23640889 -1.1.1.153 9,10-phenanthrenequinone homo sapiens 0.627 0.3865 2 PMID:23640889 -1.1.1.153 menadione homo sapiens 1.45 1.45 1 PMID:23640889 -1.1.1.153 sepiapterin homo sapiens 1.61 1.61 1 PMID:23640889 -1.1.1.154 (s)-ureidoglycolate escherichia coli 57.0 57.0 1 PMID:23437267 -1.1.1.154 nad+ escherichia coli 62.0 62.0 1 PMID:23437267 -1.1.1.157 3-acetoacetyl-coa clostridium acetobutylicum 13000.0 13000.0 1 PMID:30387779 -1.1.1.157 nadh clostridium acetobutylicum 8500.0 8500.0 1 PMID:30387779 -1.1.1.159 chenodeoxycholic acid clostridium sardiniense 2.34 2.34 1 PMID:30734123 -1.1.1.159 chenodeoxycholic acid escherichia coli 8.18 8.18 1 PMID:2007545 -1.1.1.159 cholic acid escherichia coli 151.0 107.15 2 PMID:2007545;PMID:9722677 -1.1.1.159 glycocholic acid escherichia coli 0.417 0.417 1 PMID:2007545 -1.1.1.159 nadp+ clostridium sardiniense 13.76 4.89 3 PMID:25131646;PMID:28826103;PMID:30734123 -1.1.1.159 taurochenodeoxycholic acid escherichia coli 3.43 3.43 1 PMID:2007545 -1.1.1.159 taurocholic acid escherichia coli 3.13 3.13 1 PMID:2007545 -1.1.1.16 galactitol rhizobium leguminosarum 13.91 13.91 1 PMID:24731824 -1.1.1.168 2-dehydropantolactone candida dubliniensis 59.0 59.0 1 PMID:31000167 -1.1.1.169 (r)-4-dehydropantoate staphylococcus aureus 16.6 16.6 1 PMID:25946571 -1.1.1.169 (r)-pantoate thermococcus kodakarensis 3.8 3.485 2 PMID:23941541 -1.1.1.169 2-dehydropantoate escherichia coli 25.0 25.0 1 PMID:17229734 -1.1.1.169 2-dehydropantoate thermococcus kodakarensis 23.1 23.1 1 PMID:23941541 -1.1.1.169 ketopantoate escherichia coli 40.0 24.0 2 PMID:11724562 -1.1.1.169 nad+ thermococcus kodakarensis 2.41 2.41 1 PMID:23941541 -1.1.1.169 nadh thermococcus kodakarensis 19.7 19.7 1 PMID:23941541 -1.1.1.169 nadph escherichia coli 25.0 25.0 1 PMID:17229734 -1.1.1.169 nadph staphylococcus aureus 16.8 16.8 1 PMID:25946571 -1.1.1.169 nadph thermococcus kodakarensis 2.22 2.22 1 PMID:23941541 -1.1.1.17 d-fructose 6-phosphate acinetobacter baumannii 144.69 144.69 1 PMID:35363566 -1.1.1.17 d-fructose 6-phosphate aspergillus fumigatus 132.0 128.5 2 PMID:18452897;PMID:21299839 -1.1.1.17 d-mannitol 1-phosphate aspergillus fumigatus 10.6 9.55 2 PMID:18452897;PMID:21299839 -1.1.1.17 nadh acinetobacter baumannii 61.98 61.98 1 PMID:35363566 -1.1.1.17 nadph acinetobacter baumannii 141.2 141.2 1 PMID:35363566 -1.1.1.173 l-rhamnose debaryomyces hansenii 2860.0 2860.0 1 PMID:18505728 -1.1.1.173 l-rhamnose scheffersomyces stipitis 1510.0 1510.0 1 PMID:18505728 -1.1.1.175 d-xylono-1,4-lactone caulobacter vibrioides 1.44 1.44 1 PMID:29959017 -1.1.1.175 d-xylose caulobacter vibrioides 30.3 24.45 4 PMID:22709678;PMID:29959017 -1.1.1.175 l-arabinose caulobacter vibrioides 29.2 24.2 3 PMID:22709678 -1.1.1.175 nad+ caulobacter vibrioides 35.7 31.0 3 PMID:22709678 -1.1.1.176 12-oxo-deoxycholic acid eggerthella sp. cag:298 6.63 6.63 1 PMID:29330189 -1.1.1.176 12-oxolithocholic acid [clostridium] hylemonae 45.09 45.09 1 PMID:29549099 -1.1.1.176 12-oxolithocholic acid [clostridium] scindens 31.13 31.13 1 PMID:29549099 -1.1.1.176 12-oxolithocholic acid eggerthella lenta 2.03 2.03 1 PMID:29617190 -1.1.1.176 12-oxolithocholic acid peptacetobacter hiranonis 72.09 72.09 1 PMID:29549099 -1.1.1.176 deoxycholic acid [clostridium] hylemonae 72.52 72.52 1 PMID:29549099 -1.1.1.176 deoxycholic acid [clostridium] scindens 90.93 90.93 1 PMID:29549099 -1.1.1.176 deoxycholic acid eggerthella lenta 28.085 28.085 1 PMID:29617190 -1.1.1.176 deoxycholic acid eggerthella sp. cag:298 10.0 10.0 1 PMID:29330189 -1.1.1.176 deoxycholic acid peptacetobacter hiranonis 130.62 130.62 1 PMID:29549099 -1.1.1.176 nadp+ [clostridium] hylemonae 66.72 66.72 1 PMID:29549099 -1.1.1.176 nadp+ [clostridium] scindens 90.74 90.74 1 PMID:29549099 -1.1.1.176 nadp+ peptacetobacter hiranonis 129.75 129.75 1 PMID:29549099 -1.1.1.176 nadph [clostridium] hylemonae 44.52 44.52 1 PMID:29549099 -1.1.1.176 nadph [clostridium] scindens 26.71 26.71 1 PMID:29549099 -1.1.1.176 nadph peptacetobacter hiranonis 76.24 76.24 1 PMID:29549099 -1.1.1.179 2-deoxy-d-glucose sus scrofa 22.0 22.0 1 PMID:2327952 -1.1.1.179 d-arabinose sus scrofa 9.0 9.0 1 PMID:2327952 -1.1.1.179 d-galactose sus scrofa 12.0 12.0 1 PMID:2327952 -1.1.1.179 d-glucose haloarcula marismortui 273.0 273.0 1 PMID:15342590 -1.1.1.179 d-glucose sus scrofa 16.0 16.0 1 PMID:2327952 -1.1.1.179 d-glucose trichoderma reesei 5.7 5.7 1 PMID:18031347 -1.1.1.179 d-ribose haloarcula marismortui 360.0 360.0 1 PMID:15342590 -1.1.1.179 d-ribose sus scrofa 40.0 40.0 1 PMID:2327952 -1.1.1.179 d-xylose haloarcula marismortui 356.0 356.0 1 PMID:15342590 -1.1.1.179 d-xylose macaca fascicularis 2.6 2.6 1 PMID:18453689 -1.1.1.179 d-xylose paenarthrobacter nicotinovorans 14.9 14.9 1 PMID:23063486 -1.1.1.179 d-xylose sus scrofa 58.0 58.0 1 PMID:2327952 -1.1.1.179 d-xylose trichoderma reesei 21.8 21.8 1 PMID:18031347 -1.1.1.179 l-arabinose sus scrofa 45.0 45.0 1 PMID:2327952 -1.1.1.179 nad+ paenarthrobacter nicotinovorans 1.5 1.5 1 PMID:23063486 -1.1.1.179 nadp+ paenarthrobacter nicotinovorans 10.5 10.5 1 PMID:23063486 -1.1.1.18 myo-inositol bacillus subtilis 58.0 58.0 1 PMID:17539607 -1.1.1.183 geraniol zingiber officinale 5.4 5.4 2 * -1.1.1.183 nadp+ zingiber officinale 5.0 5.0 2 * -1.1.1.183 nerol zingiber officinale 4.6 4.6 2 * -1.1.1.184 (r)-2-butanol methanobacterium palustre 177.0 177.0 1 PMID:1879431 -1.1.1.184 (s)-2-butanol methanobacterium palustre 123.0 123.0 1 PMID:1879431 -1.1.1.184 1,2-naphthoquinone homo sapiens 6.7 5.085 4 PMID:23295225 -1.1.1.184 1,4-naphthoquinone homo sapiens 0.55 0.41500000000000004 4 PMID:23295225 -1.1.1.184 1-(3-methyl-1,4-dioxidoquinoxalin-2-yl)ethanone gallus gallus 0.00062 0.00062 1 PMID:22266778 -1.1.1.184 1-(3-methyl-1,4-dioxidoquinoxalin-2-yl)ethanone sus scrofa 0.00027 0.00027 1 PMID:22266778 -1.1.1.184 1-(3-methyl-4-oxidoquinoxalin-2-yl)ethanone gallus gallus 2.72 2.72 1 PMID:22266778 -1.1.1.184 1-(3-methyl-4-oxidoquinoxalin-2-yl)ethanone sus scrofa 2.89 2.89 1 PMID:22266778 -1.1.1.184 1-phenylisatin canis lupus familiaris 17.0 17.0 1 PMID:17827741 -1.1.1.184 16-ketoestrone canis lupus familiaris 20.0 13.4 2 PMID:17827741 -1.1.1.184 2,2,2-trifluoroacetophenone thermotoga maritima 16.4 16.4 1 PMID:23338701 -1.1.1.184 2,3-butanediol methanobacterium palustre 26.0 26.0 1 PMID:1879431 -1.1.1.184 2,3-heptanedione canis lupus familiaris 23.0 23.0 1 PMID:17827741 -1.1.1.184 2,3-hexanedione canis lupus familiaris 24.0 24.0 1 PMID:17827741 -1.1.1.184 2,3-hexanedione homo sapiens 5.13 3.325 4 PMID:23295225 -1.1.1.184 2,3-pentanedione canis lupus familiaris 23.0 23.0 1 PMID:17827741 -1.1.1.184 2,3-pentanedione gluconobacter oxydans 36.7 23.700000000000003 2 PMID:20414648 -1.1.1.184 2-butanol methanobacterium palustre 149.0 149.0 1 PMID:1879431 -1.1.1.184 2-butanone methanobacterium palustre 86.0 86.0 1 PMID:1879431 -1.1.1.184 2-hydroxyacetophenone candida parapsilosis 1.48 1.4 4 PMID:18566346;PMID:19201968 -1.1.1.184 2-pentanol methanobacterium palustre 5.0 5.0 1 PMID:1879431 -1.1.1.184 2-pentanone methanobacterium palustre 18.0 18.0 1 PMID:1879431 -1.1.1.184 2-propanol methanobacterium palustre 243.0 243.0 1 PMID:1879431 -1.1.1.184 3-glutathionyl-4-hydroxynonanal homo sapiens 6.75 6.75 1 PMID:25680283 -1.1.1.184 3-glutathionyl-hexanal homo sapiens 30.5 30.5 1 PMID:27562619 -1.1.1.184 3-glutathionyl-nonanal homo sapiens 30.8 30.8 1 PMID:27562619 -1.1.1.184 3-glutathionyl-propanal homo sapiens 190.8 190.8 1 PMID:27562619 -1.1.1.184 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone homo sapiens 2.02 1.51 2 PMID:23295225 -1.1.1.184 4-benzoylpyridine canis lupus familiaris 17.0 17.0 1 PMID:17827741 -1.1.1.184 4-benzoylpyridine cricetulus griseus 1.967 0.5465 4 PMID:18983987;PMID:18983989 -1.1.1.184 4-benzoylpyridine homo sapiens 1.2 0.275 6 PMID:18493841;PMID:18983987;PMID:23295225 -1.1.1.184 4-benzoylpyridine rattus norvegicus 0.23 0.23 1 PMID:18983987 -1.1.1.184 4-hexanoylpyridine canis lupus familiaris 17.0 17.0 1 PMID:17827741 -1.1.1.184 4-nitrobenzaldehyde cricetulus griseus 1.087 0.3 3 PMID:18983989 -1.1.1.184 4-nitrobenzaldehyde gallus gallus 3.48 3.48 1 PMID:26206323 -1.1.1.184 4-nitrobenzaldehyde homo sapiens 0.0098 0.0098 1 PMID:18493841 -1.1.1.184 4-oxonon-2-enal homo sapiens 220.0 220.0 1 PMID:15476404 -1.1.1.184 9,10-phenanthrenequinone aeropyrum pernix 1.27 1.27 1 PMID:27444325 -1.1.1.184 9,10-phenanthrenequinone canis lupus familiaris 20.0 20.0 1 PMID:17827741 -1.1.1.184 9,10-phenanthrenequinone gallus gallus 2.33 2.33 1 PMID:26206323 -1.1.1.184 9,10-phenanthrenequinone homo sapiens 9.77 5.25 5 PMID:21256830;PMID:23295225 -1.1.1.184 9,10-phenantrenequinone homo sapiens 66.7 66.7 1 PMID:28274719 -1.1.1.184 9-cis-retinal canis lupus familiaris 0.07 0.07 1 PMID:17827741 -1.1.1.184 acenaphthenequinone canis lupus familiaris 13.0 13.0 1 PMID:17827741 -1.1.1.184 acetoin methanobacterium palustre 183.0 183.0 1 PMID:1879431 -1.1.1.184 acetone gallus gallus 0.18 0.18 1 PMID:26206323 -1.1.1.184 all-trans-retinal canis lupus familiaris 0.08 0.08 1 PMID:17827741 -1.1.1.184 all-trans-retinol canis lupus familiaris 0.01 0.01 1 PMID:17827741 -1.1.1.184 benzoylformic acid ethyl ester canis lupus familiaris 32.0 32.0 1 PMID:17827741 -1.1.1.184 cycloheptanone methanobacterium palustre 6.0 6.0 1 PMID:1879431 -1.1.1.184 cyclohexanol methanobacterium palustre 5.0 5.0 1 PMID:1879431 -1.1.1.184 cyclohexanone methanobacterium palustre 86.0 86.0 1 PMID:1879431 -1.1.1.184 cyclopentanol methanobacterium palustre 106.0 106.0 1 PMID:1879431 -1.1.1.184 cyclopentanone methanobacterium palustre 80.0 80.0 1 PMID:1879431 -1.1.1.184 daunorubicin canis lupus familiaris 3.52 3.52 1 PMID:25918240 -1.1.1.184 daunorubicin homo sapiens 91.0 1.605 6 PMID:17344335;PMID:19204081;PMID:23295225 -1.1.1.184 diacetyl methanobacterium palustre 609.0 609.0 1 PMID:1879431 -1.1.1.184 doxorubicin homo sapiens 0.21 0.16499999999999998 4 PMID:18635746;PMID:19204081 -1.1.1.184 doxorubicin mus musculus 0.015 0.008199999999999999 2 PMID:31955137 -1.1.1.184 estrone gallus gallus 0.45 0.45 1 PMID:26206323 -1.1.1.184 ethyl 2-methylacetoacetate thermotoga maritima 12.5 12.5 1 PMID:23338701 -1.1.1.184 ethyl 2-oxo-4-phenylbutyrate thermotoga maritima 11.2 11.2 1 PMID:23338701 -1.1.1.184 ethyl 4-chloro-3-oxobutanoate aeropyrum pernix 1.05 1.05 1 PMID:27444325 -1.1.1.184 glutathione-4-oxonon-2-enal homo sapiens 8.6 8.6 1 PMID:15476404 -1.1.1.184 glutathionyl-nonanal homo sapiens 30.8 30.8 1 PMID:28274719 -1.1.1.184 heptanophenone canis lupus familiaris 10.0 10.0 1 PMID:17827741 -1.1.1.184 hexanophenone canis lupus familiaris 25.0 25.0 1 PMID:17827741 -1.1.1.184 isatin canis lupus familiaris 14.0 10.15 2 PMID:17827741 -1.1.1.184 isatin cricetulus griseus 1.225 0.583 3 PMID:18983989 -1.1.1.184 isatin gallus gallus 2.55 2.55 1 PMID:26206323 -1.1.1.184 isatin homo sapiens 9.77 0.235 4 PMID:23295225 -1.1.1.184 menadione canis lupus familiaris 8.48 4.495 2 PMID:17827741;PMID:25918240 -1.1.1.184 menadione cricetulus griseus 0.0483 0.0483 1 PMID:18983987 -1.1.1.184 menadione gallus gallus 4.17 2.2199999999999998 2 PMID:22266778;PMID:26206323 -1.1.1.184 menadione homo sapiens 246.0 0.33 13 PMID:15476404;PMID:15537833;PMID:17344335;PMID:18493841;PMID:18983987;PMID:19204081;PMID:23295225 -1.1.1.184 menadione sus scrofa 0.15 0.15 1 PMID:22266778 -1.1.1.184 methyl glyoxal kluyveromyces marxianus 4.0 3.25 2 PMID:26223585 -1.1.1.184 methylglyoxal gluconobacter oxydans 23.8 23.8 1 PMID:20414648 -1.1.1.184 n-butyrophenone canis lupus familiaris 15.0 15.0 1 PMID:17827741 -1.1.1.184 nadh candida parapsilosis 1.32 1.32 1 PMID:18391419 -1.1.1.184 nadp+ methanobacterium palustre 243.0 243.0 1 PMID:1879431 -1.1.1.184 nadph candida parapsilosis 1.48 1.48 1 PMID:18391419 -1.1.1.184 nadph homo sapiens 179.0 25.25 4 PMID:15537833;PMID:17344335;PMID:27562619 -1.1.1.184 nadph kluyveromyces marxianus 3.67 3.17 2 PMID:26223585 -1.1.1.184 nadph methanobacterium palustre 129.0 129.0 1 PMID:1879431 -1.1.1.184 nadph mus musculus 0.036 0.01805 2 PMID:31955137 -1.1.1.184 nadph starmerella magnoliae 870.0 870.0 1 PMID:15784983 -1.1.1.184 oracin homo sapiens 1.67 1.025 2 PMID:23295225 -1.1.1.184 p-toluquinone aeropyrum pernix 2.5 2.5 1 PMID:27444325 -1.1.1.184 p-toluquinone gallus gallus 3.28 3.28 1 PMID:26206323 -1.1.1.184 phenylglyoxal gluconobacter oxydans 39.3 39.3 1 PMID:20414648 -1.1.1.184 propanone methanobacterium palustre 129.0 129.0 1 PMID:1879431 -1.1.1.184 prostaglandin e2 gallus gallus 0.68 0.68 1 PMID:26206323 -1.1.1.184 prostaglandin e2 homo sapiens 25.0 25.0 1 PMID:17344335 -1.1.1.184 s-1-phenyl-1-butanol canis lupus familiaris 3.5 3.5 1 PMID:17827741 -1.1.1.184 s-nitrosoglutathione homo sapiens 2.62 2.62 1 PMID:21256830 -1.1.1.184 testosterone gallus gallus 0.6 0.6 1 PMID:26206323 -1.1.1.184 valerophenone canis lupus familiaris 11.0 11.0 1 PMID:17827741 -1.1.1.188 9,10-phenanthrenequinone homo sapiens 1.4 1.4 1 PMID:17950253 -1.1.1.188 9alpha,11beta-prostaglandin f2 mus musculus 0.055 0.055 1 PMID:31479646 -1.1.1.188 androst-4-ene-3,17-dione homo sapiens 0.0027 0.0027 1 PMID:17950253 -1.1.1.188 prostaglandin d2 mus musculus 0.093 0.093 1 PMID:31479646 -1.1.1.188 prostaglandin h2 mus musculus 0.2467 0.2467 1 PMID:18006499 -1.1.1.188 prostaglandin h2 sus scrofa 0.2467 0.2467 1 * -1.1.1.19 d-galacturonate penicillium camemberti 18.5 11.25 4 PMID:31756465 -1.1.1.19 d-glucuronate penicillium camemberti 13.0 9.75 4 PMID:31756465 -1.1.1.19 d-glucurono-3,6-lactone penicillium camemberti 2.3 2.3 1 PMID:31756465 -1.1.1.19 nadh penicillium camemberti 7.4 7.4 1 PMID:31756465 -1.1.1.19 nadph penicillium camemberti 9.6 9.6 1 PMID:31756465 -1.1.1.192 nad+ geobacillus thermodenitrificans 38.5 38.5 1 PMID:19383697 -1.1.1.192 nadp+ geobacillus thermodenitrificans 283.1 283.1 1 PMID:19383697 -1.1.1.192 nadph geobacillus thermodenitrificans 4808.0 4808.0 1 PMID:19383697 -1.1.1.194 coniferyl alcohol streptomyces sp. 25.8 25.8 1 PMID:23500723 -1.1.1.195 3-phenyl-1-propanol streptomyces sp. 11.2 11.2 1 PMID:21897026 -1.1.1.195 4-coumaraldehyde arabidopsis thaliana 6.8 6.8 1 PMID:23296200 -1.1.1.195 4-coumaryl aldehyde artemisia annua 12.36 12.36 1 PMID:29971081 -1.1.1.195 4-coumaryl aldehyde oryza sativa japonica group 13.86 0.076 3 PMID:30332817 -1.1.1.195 4-coumaryl aldehyde sorghum bicolor 11.93 7.05 2 PMID:28606901 -1.1.1.195 4-coumarylaldehyde plagiochasma appendiculatum 0.367 0.32 2 PMID:23774375 -1.1.1.195 5-hydroxyconiferylaldehyde plagiochasma appendiculatum 0.007 0.006 2 PMID:23774375 -1.1.1.195 acetaldehyde helicobacter pylori 16.7 16.7 1 PMID:15720399 -1.1.1.195 allyl alcohol streptomyces sp. 32.9 32.9 1 PMID:21897026 -1.1.1.195 benzaldehyde helicobacter pylori 2.5 2.4 2 PMID:15720399 -1.1.1.195 benzyl alcohol helicobacter pylori 8.4 8.4 1 PMID:15720399 -1.1.1.195 butanol helicobacter pylori 5.7 5.7 1 PMID:15720399 -1.1.1.195 caffeylaldehyde plagiochasma appendiculatum 0.072 0.067 2 PMID:23774375 -1.1.1.195 cinnamaldehyde geobacillus stearothermophilus 55.0 55.0 1 PMID:23686507 -1.1.1.195 cinnamaldehyde hibiscus cannabinus 1437.0 1437.0 1 * -1.1.1.195 cinnamaldehyde leucaena leucocephala 18.0 11.815 2 PMID:24064207;PMID:24532464 -1.1.1.195 cinnamaldehyde streptomyces sp. 14.4 14.4 1 PMID:21897026 -1.1.1.195 cinnamaldehyde synechocystis sp. 107.9 107.9 1 PMID:19411329 -1.1.1.195 cinnamyl alcohol geobacillus stearothermophilus 43.0 43.0 1 PMID:23686507 -1.1.1.195 cinnamyl alcohol helicobacter pylori 13.3 13.3 1 PMID:15720399 -1.1.1.195 cinnamyl alcohol leucaena leucocephala 16.2 11.305 2 PMID:24064207;PMID:24532464 -1.1.1.195 cinnamyl alcohol streptomyces sp. 18.1 18.1 1 PMID:21897026 -1.1.1.195 cinnamyl alcohol synechocystis sp. 60.78 60.78 1 PMID:19411329 -1.1.1.195 cinnamyl aldehyde helicobacter pylori 7.7 7.7 1 PMID:15720399 -1.1.1.195 cinnamyl aldehyde oryza sativa japonica group 9.05 0.311 3 PMID:30332817 -1.1.1.195 coniferaldehyde plagiochasma appendiculatum 0.085 0.0785 2 PMID:23774375 -1.1.1.195 coniferaldehyde sinopodophyllum hexandrum 12.0 9.9 4 PMID:27387305 -1.1.1.195 coniferyl alcohol helicobacter pylori 3.5 3.5 1 PMID:15720399 -1.1.1.195 coniferyl alcohol leucaena leucocephala 16.3 12.525 2 PMID:24064207;PMID:24532464 -1.1.1.195 coniferyl alcohol nicotiana tabacum 0.99 0.71 2 PMID:16270228 -1.1.1.195 coniferyl alcohol panicum virgatum 13.2 13.2 1 * -1.1.1.195 coniferyl aldehyde artemisia annua 13.82 13.82 1 PMID:29971081 -1.1.1.195 coniferyl aldehyde carthamus tinctorius 0.032 0.0121 3 * -1.1.1.195 coniferyl aldehyde helicobacter pylori 27.4 27.4 1 PMID:15720399 -1.1.1.195 coniferyl aldehyde hibiscus cannabinus 7564.0 7564.0 1 * -1.1.1.195 coniferyl aldehyde leucaena leucocephala 16.56 10.129999999999999 2 PMID:24064207;PMID:24532464 -1.1.1.195 coniferyl aldehyde medicago truncatula 9.1 4.6 2 PMID:25217505 -1.1.1.195 coniferyl aldehyde nicotiana tabacum 0.24 0.20500000000000002 2 PMID:16270228 -1.1.1.195 coniferyl aldehyde oryza sativa 1.3 1.3 1 PMID:16443696 -1.1.1.195 coniferyl aldehyde oryza sativa japonica group 30.13 0.284 3 PMID:30332817 -1.1.1.195 coniferyl aldehyde panicum virgatum 138.0 118.8 2 * -1.1.1.195 coniferyl aldehyde populus tomentosa 45.42 27.05 4 PMID:25096165 -1.1.1.195 coniferyl aldehyde sorghum bicolor 20.28 16.525 2 PMID:28606901 -1.1.1.195 coumaryl alcohol panicum virgatum 24.7 24.7 1 * -1.1.1.195 ethanol helicobacter pylori 7.1 7.1 1 PMID:15720399 -1.1.1.195 nad+ eucalyptus gunnii 0.0242 0.0242 1 PMID:7547988 -1.1.1.195 nad+ geobacillus stearothermophilus 33.0 33.0 1 PMID:23686507 -1.1.1.195 nad+ streptomyces sp. 19.9 19.9 1 PMID:21897026 -1.1.1.195 nadh geobacillus stearothermophilus 43.0 43.0 1 PMID:23686507 -1.1.1.195 nadp+ eucalyptus gunnii 0.0555 0.0555 1 PMID:7547988 -1.1.1.195 nadp+ helicobacter pylori 15.5 15.5 1 PMID:15720399 -1.1.1.195 nadp+ leucaena leucocephala 23.3 16.26 2 PMID:24064207;PMID:24532464 -1.1.1.195 nadph eucalyptus gunnii 0.49 0.49 1 PMID:7547988 -1.1.1.195 nadph helicobacter pylori 25.2 25.2 1 PMID:15720399 -1.1.1.195 nadph leucaena leucocephala 28.8 22.055 2 PMID:24064207;PMID:24532464 -1.1.1.195 p-coumaryl aldehyde leucaena leucocephala 22.5 22.5 1 PMID:24064207 -1.1.1.195 p-coumaryl aldehyde medicago truncatula 15.6 8.03 2 PMID:25217505 -1.1.1.195 propanol helicobacter pylori 12.8 12.8 1 PMID:15720399 -1.1.1.195 sinapaldehyde plagiochasma appendiculatum 0.006 0.0055 2 PMID:23774375 -1.1.1.195 sinapaldehyde sinopodophyllum hexandrum 8.3 3.08 4 PMID:27387305 -1.1.1.195 sinapyl alcohol leucaena leucocephala 16.0 15.190000000000001 2 PMID:24064207;PMID:24532464 -1.1.1.195 sinapyl alcohol panicum virgatum 46.4 46.4 1 * -1.1.1.195 sinapyl aldehyde artemisia annua 14.03 14.03 1 PMID:29971081 -1.1.1.195 sinapyl aldehyde carthamus tinctorius 0.041 0.0053 3 * -1.1.1.195 sinapyl aldehyde hibiscus cannabinus 9368.0 9368.0 1 * -1.1.1.195 sinapyl aldehyde leucaena leucocephala 32.2 32.2 1 PMID:24064207 -1.1.1.195 sinapyl aldehyde medicago truncatula 10.2 5.111999999999999 2 PMID:25217505 -1.1.1.195 sinapyl aldehyde oryza sativa 3.4 3.4 1 PMID:16443696 -1.1.1.195 sinapyl aldehyde oryza sativa japonica group 41.19 0.128 3 PMID:30332817 -1.1.1.195 sinapyl aldehyde panicum virgatum 196.0 195.5 2 * -1.1.1.195 sinapyl aldehyde populus tomentosa 16.59 13.34 4 PMID:25096165 -1.1.1.195 sinapyl aldehyde sorghum bicolor 31.75 22.145 2 PMID:28606901 -1.1.1.198 (+)-borneol artemisia annua 0.0058 0.0058 1 * -1.1.1.198 (+)-borneol cinnamomum camphora 0.0054 0.0054 1 PMID:33243711 -1.1.1.198 (+)-borneol lavandula x intermedia 0.0004 0.0004 1 PMID:23058847 -1.1.1.198 (+)-borneol pseudomonas monteilii 209.0 142.0 4 PMID:32732035 -1.1.1.198 (+)-borneol pseudomonas putida 0.89 0.89 1 PMID:33846823 -1.1.1.198 (+)-borneol pseudomonas sp. 0.75 0.75 1 PMID:27542933 -1.1.1.198 (+)-borneol pseudomonas sp. atcc 17453 0.89 0.89 1 PMID:33846823 -1.1.1.198 (+)-borneol pseudomonas sp. tcu-hl1 27.8 17.0 5 PMID:32738440 -1.1.1.198 (+)-borneol salvia officinalis 0.005 0.005 1 * -1.1.1.198 (-)-borneol cinnamomum camphora 0.0021 0.0021 1 PMID:33243711 -1.1.1.198 (-)-borneol pseudomonas monteilii 29.4 20.35 2 PMID:32732035 -1.1.1.198 (-)-borneol pseudomonas sp. atcc 17453 0.97 0.97 1 PMID:33846823 -1.1.1.198 (-)-borneol pseudomonas sp. tcu-hl1 18.5 12.4 3 PMID:32738440 -1.1.1.198 nad+ pseudomonas sp. atcc 17453 0.006 0.006 1 PMID:33846823 -1.1.1.198 nad+ salvia officinalis 0.0049 0.0049 1 * -1.1.1.2 (+)-camphorquinone sus scrofa 5.6 5.6 1 PMID:4402936 -1.1.1.2 (2r,3r)-2,3-butanediol thermococcus guaymasensis 740.0 740.0 1 PMID:21515780 -1.1.1.2 (2s,3s)-2,3-butanediol thermococcus guaymasensis 512.0 512.0 1 PMID:21515780 -1.1.1.2 1,5-pentanediol mycobacterium sp. 5.31 5.31 1 PMID:26923741 -1.1.1.2 1-pentanol saccharomyces cerevisiae 918.0 918.0 1 PMID:11742541 -1.1.1.2 2-butanol thermococcus guaymasensis 833.0 833.0 1 PMID:21515780 -1.1.1.2 2-butanone thermococcus guaymasensis 190.0 190.0 1 PMID:21515780 -1.1.1.2 2-hydroxytetrahydrofuran vanderwaltozyma polyspora 0.00044 0.00044 1 * -1.1.1.2 2-propanol thermococcus sibiricus 0.53 0.53 1 PMID:20418438 -1.1.1.2 3-methyl-1,5-pentanediol mycobacterium sp. 7.84 7.84 1 PMID:26923741 -1.1.1.2 3-methyl-1-butanol saccharomyces cerevisiae 2866.0 1519.5 2 PMID:11742541 -1.1.1.2 3-methylbutanal saccharomyces cerevisiae 9581.0 4938.5 2 PMID:11742541 -1.1.1.2 3-pyridinecarboxaldehyde sus scrofa 26.8 26.8 1 PMID:4402936 -1.1.1.2 3-pyridinemethanol sus scrofa 0.07 0.07 1 PMID:4402936 -1.1.1.2 4-carboxybenzaldehyde sus scrofa 21.7 21.7 1 PMID:4402936 -1.1.1.2 4-cyanobenzaldehyde sus scrofa 16.6 16.6 1 PMID:4402936 -1.1.1.2 4-hydroxy-3-methoxybenzyl alcohol homo sapiens 0.148 0.148 1 PMID:16919 -1.1.1.2 4-nitrobenzaldehyde sus scrofa 22.0 22.0 1 PMID:4402936 -1.1.1.2 4-pyridinecarboxaldehyde sus scrofa 19.3 19.3 1 PMID:4402936 -1.1.1.2 acetaldehyde escherichia coli 53.5 53.5 1 PMID:18211903 -1.1.1.2 acetaldehyde geobacillus thermodenitrificans 138.1 138.1 1 PMID:19383697 -1.1.1.2 acetaldehyde pseudothermotoga hypogea 15.0 15.0 1 PMID:17294170 -1.1.1.2 acetaldehyde pyrococcus furiosus 5.5 5.5 1 PMID:9973342 -1.1.1.2 acetaldehyde synechocystis sp. 157.6 157.6 1 PMID:19411329 -1.1.1.2 acetaldehyde thermococcus sp. 23.6 23.25 2 PMID:19115036 -1.1.1.2 acetoin thermococcus guaymasensis 142.0 142.0 1 PMID:21515780 -1.1.1.2 acetophenone levilactobacillus brevis 44.5 44.5 1 PMID:15896805 -1.1.1.2 acrolein escherichia coli 62.5 62.5 1 PMID:18211903 -1.1.1.2 benzylalcohol homo sapiens 0.0733 0.0733 1 PMID:16919 -1.1.1.2 butan-1-ol mycobacterium sp. 7.02 7.02 1 PMID:26923741 -1.1.1.2 butanal pectobacterium atrosepticum 20.1 20.1 1 PMID:24265029 -1.1.1.2 butanal synechocystis sp. 156.6 156.3 2 PMID:19411329 -1.1.1.2 butanaldehyde escherichia coli 59.5 59.5 1 PMID:18211903 -1.1.1.2 butanol pseudothermotoga hypogea 48.0 48.0 1 PMID:17294170 -1.1.1.2 butanol synechocystis sp. 17.05 17.05 1 PMID:19411329 -1.1.1.2 butyraldehyde pseudothermotoga hypogea 48.0 48.0 1 PMID:17294170 -1.1.1.2 cinnamaldehyde saccharomyces cerevisiae 7913.0 4110.0 2 PMID:11742541 -1.1.1.2 cinnamaldehyde synechocystis sp. 107.9 107.9 1 PMID:19411329 -1.1.1.2 cinnamyl alcohol saccharomyces cerevisiae 3404.0 846.0 4 PMID:11742541 -1.1.1.2 cinnamyl alcohol synechocystis sp. 60.78 60.78 1 PMID:19411329 -1.1.1.2 d-glucuronate sus scrofa 11.6 11.6 1 PMID:4402936 -1.1.1.2 d-glyceraldehyde sus scrofa 14.4 14.4 1 PMID:4402936 -1.1.1.2 d-lactaldehyde sus scrofa 13.7 13.7 1 PMID:4402936 -1.1.1.2 d-xylose thermococcus sibiricus 0.7 0.7 1 PMID:20418438 -1.1.1.2 diacetyl thermococcus guaymasensis 202.0 202.0 1 PMID:21515780 -1.1.1.2 ethanol geobacillus thermodenitrificans 136.2 136.2 1 PMID:19383697 -1.1.1.2 ethanol pseudothermotoga hypogea 14.0 14.0 1 PMID:17294170 -1.1.1.2 ethanol pyrococcus furiosus 19.2 19.2 1 PMID:9973342 -1.1.1.2 ethanol synechocystis sp. 27.35 27.35 1 PMID:19411329 -1.1.1.2 ethanol thermococcus sp. 84.0 82.5 2 PMID:19115036 -1.1.1.2 glycerol homo sapiens 0.0283 0.0283 1 PMID:16919 -1.1.1.2 glycerol sus scrofa 0.612 0.612 1 PMID:4402936 -1.1.1.2 hexanal saccharomyces cerevisiae 359.0 359.0 1 PMID:11742541 -1.1.1.2 hexanol saccharomyces cerevisiae 10.7 10.7 1 PMID:11742541 -1.1.1.2 l-arabitol sus scrofa 1.77 1.77 1 PMID:4402936 -1.1.1.2 malondialdehyde escherichia coli 60.1 60.1 1 PMID:18211903 -1.1.1.2 meso-2,3-butanediol thermococcus guaymasensis 952.0 952.0 1 PMID:21515780 -1.1.1.2 methylglyoxal pyrococcus furiosus 3.7 3.7 1 PMID:9973342 -1.1.1.2 nad+ geobacillus thermodenitrificans 38.5 38.5 1 PMID:19383697 -1.1.1.2 nad+ pyrococcus furiosus 2.4 2.4 1 PMID:9973342 -1.1.1.2 nadh geobacillus thermodenitrificans 4808.2 4808.2 1 PMID:19383697 -1.1.1.2 nadh scheffersomyces stipitis 6.23 4.465 2 PMID:23912116 -1.1.1.2 nadp+ geobacillus thermodenitrificans 283.1 283.1 1 PMID:19383697 -1.1.1.2 nadp+ levilactobacillus brevis 4.4 4.4 1 PMID:15896805 -1.1.1.2 nadp+ mycobacterium sp. 13.41 13.41 1 PMID:26923741 -1.1.1.2 nadp+ pseudothermotoga hypogea 50.0 50.0 1 PMID:17294170 -1.1.1.2 nadp+ pyrococcus furiosus 15.8 15.8 1 PMID:9973342 -1.1.1.2 nadp+ thermococcus guaymasensis 1333.0 1333.0 1 PMID:21515780 -1.1.1.2 nadp+ thermococcus sibiricus 0.45 0.45 1 PMID:20418438 -1.1.1.2 nadp+ thermococcus sp. 84.0 82.5 2 PMID:19115036 -1.1.1.2 nadph levilactobacillus brevis 38.1 38.1 1 PMID:15896805 -1.1.1.2 nadph pseudothermotoga hypogea 52.0 52.0 1 PMID:17294170 -1.1.1.2 nadph pyrococcus furiosus 6.3 6.3 1 PMID:9973342 -1.1.1.2 nadph scheffersomyces stipitis 6.5 4.75 3 PMID:23912116 -1.1.1.2 nadph thermococcus guaymasensis 158.0 158.0 1 PMID:21515780 -1.1.1.2 nadph thermococcus sibiricus 1.51 1.51 1 PMID:20418438 -1.1.1.2 nadph thermococcus sp. 24.0 24.0 2 PMID:19115036 -1.1.1.2 octan-1-ol geobacillus thermodenitrificans 260.7 260.7 1 PMID:19383697 -1.1.1.2 octanal geobacillus thermodenitrificans 518.4 518.4 1 PMID:19383697 -1.1.1.2 p-nitrobenzaldehyde homo sapiens 9.5 9.5 1 PMID:16919 -1.1.1.2 pentanal pectobacterium atrosepticum 49.2 49.2 1 PMID:24265029 -1.1.1.2 pentanal saccharomyces cerevisiae 11920.0 6149.0 2 PMID:11742541 -1.1.1.2 pentanal synechocystis sp. 159.1 159.05 2 PMID:19411329 -1.1.1.2 pentanol synechocystis sp. 13.15 13.15 1 PMID:19411329 -1.1.1.2 phenylacetaldehyde pyrococcus furiosus 10.4 10.4 1 PMID:9973342 -1.1.1.2 phenylethanediol homo sapiens 0.08 0.08 1 PMID:16919 -1.1.1.2 phenylethanol homo sapiens 0.0283 0.0283 1 PMID:16919 -1.1.1.2 phenylethanol levilactobacillus brevis 5.4 5.4 1 PMID:15896805 -1.1.1.2 phenylethanol saccharomyces cerevisiae 1132.0 1132.0 1 PMID:11742541 -1.1.1.2 propane-1,2-diol homo sapiens 0.0433 0.0433 1 PMID:16919 -1.1.1.2 propionaldehyde escherichia coli 45.1 45.1 1 PMID:18211903 -1.1.1.2 pyruvaldehyde thermococcus sibiricus 2.04 2.04 1 PMID:20418438 -1.1.1.2 veratraldehyde saccharomyces cerevisiae 6000.0 3131.5 2 PMID:11742541 -1.1.1.200 d-glucitol-6-phosphate malus domestica 0.222 0.11155 2 PMID:19799961 -1.1.1.200 d-glucose 6-phosphate malus domestica 0.7 0.3545 2 PMID:19799961 -1.1.1.201 7-ketolithocholic acid collinsella aerofaciens 15.8 15.8 1 PMID:21181147 -1.1.1.201 7-oxo-lithocholic acid [ruminococcus] torques 4.2 4.2 1 PMID:28116898 -1.1.1.201 dehydrocholic acid collinsella aerofaciens 14.6 14.6 1 PMID:21181147 -1.1.1.201 nadp+ collinsella aerofaciens 15.7 15.7 1 PMID:21181147 -1.1.1.201 nadph [ruminococcus] torques 4.3 4.3 1 PMID:28116898 -1.1.1.201 nadph collinsella aerofaciens 17.2 17.2 1 PMID:21181147 -1.1.1.201 ursodeoxycholic acid collinsella aerofaciens 19.6 19.6 1 PMID:21181147 -1.1.1.202 3-hydroxypropanal klebsiella pneumoniae 59.4 59.4 1 * -1.1.1.202 acetaldehyde klebsiella pneumoniae 5.2 5.2 1 * -1.1.1.202 butyraldehyde klebsiella pneumoniae 8.7 8.7 1 * -1.1.1.202 formaldehyde klebsiella pneumoniae 1.6 1.6 1 * -1.1.1.202 nad+ klebsiella pneumoniae 51.99 30.845 2 PMID:20156491 -1.1.1.202 nadh klebsiella pneumoniae 90.64 75.07 2 PMID:20156491 -1.1.1.202 propane-1,3-diol klebsiella pneumoniae 9.98 9.98 1 * -1.1.1.202 propionaldehyde klebsiella pneumoniae 1.1 1.1 1 * -1.1.1.202 valeraldehyde klebsiella pneumoniae 1.0 1.0 1 * -1.1.1.203 beta-d-galacturonate agrobacterium tumefaciens 76.0 67.5 2 PMID:25884328 -1.1.1.203 beta-d-galacturonate chromohalobacter israelensis 30.8 23.05 2 PMID:25640726 -1.1.1.203 beta-d-galacturonate ectopseudomonas mendocina 17.9 17.65 2 PMID:25640726 -1.1.1.203 beta-d-galacturonate fulvimarina pelagi 13.0 11.5 2 PMID:25884328 -1.1.1.203 beta-d-galacturonate oceanicola granulosus 4.0 3.5 2 PMID:25884328 -1.1.1.203 beta-d-galacturonate polaromonas naphthalenivorans 51.6 42.7 2 PMID:25640726 -1.1.1.203 beta-d-galacturonate pseudomonas fluorescens 17.1 17.1 1 PMID:25640726 -1.1.1.203 beta-d-galacturonate pseudomonas syringae pv. tomato 29.0 27.8 3 PMID:25640726;PMID:25884328 -1.1.1.203 beta-d-galacturonate streptomyces viridochromogenes 23.0 20.0 2 PMID:25884328 -1.1.1.203 beta-d-glucuronate agrobacterium tumefaciens 333.0 252.0 2 PMID:25884328 -1.1.1.203 beta-d-glucuronate chromohalobacter israelensis 263.0 191.0 2 PMID:25640726 -1.1.1.203 beta-d-glucuronate ectopseudomonas mendocina 159.0 130.0 2 PMID:25640726 -1.1.1.203 beta-d-glucuronate fulvimarina pelagi 82.0 70.0 2 PMID:25884328 -1.1.1.203 beta-d-glucuronate oceanicola granulosus 7.0 6.5 2 PMID:25884328 -1.1.1.203 beta-d-glucuronate polaromonas naphthalenivorans 274.0 243.0 2 PMID:25640726 -1.1.1.203 beta-d-glucuronate pseudomonas fluorescens 152.0 152.0 1 PMID:25640726 -1.1.1.203 beta-d-glucuronate pseudomonas syringae pv. tomato 217.0 108.0 3 PMID:25640726;PMID:25884328 -1.1.1.203 beta-d-glucuronate streptomyces viridochromogenes 75.0 64.0 2 PMID:25884328 -1.1.1.203 d-galacturonate agrobacterium tumefaciens 0.92 0.92 1 PMID:19060141 -1.1.1.203 d-galacturonate pseudomonas putida kt2440 0.3 0.3 1 PMID:19060141 -1.1.1.203 d-galacturonate pseudomonas syringae 26.7 26.7 1 PMID:2471 -1.1.1.203 d-galacturonate pseudomonas syringae pv. tomato 0.24 0.24 1 PMID:19060141 -1.1.1.203 d-galacturonic acid penicillium camemberti 18.5 16.05 2 PMID:31756465 -1.1.1.203 d-galacturonic acid thermobispora bispora 58.333 58.333 1 PMID:29936649 -1.1.1.203 d-glucuronate agrobacterium tumefaciens 1.9 1.9 1 PMID:19060141 -1.1.1.203 d-glucuronate pseudomonas putida kt2440 0.55 0.55 1 PMID:19060141 -1.1.1.203 d-glucuronate pseudomonas syringae 80.0 80.0 1 PMID:2471 -1.1.1.203 d-glucuronate pseudomonas syringae pv. tomato 0.74 0.74 1 PMID:19060141 -1.1.1.203 d-glucuronic acid agrobacterium tumefaciens 161.0 161.0 1 * -1.1.1.203 d-glucuronic acid penicillium camemberti 13.0 10.3 2 PMID:31756465 -1.1.1.203 d-glucuronic acid from a beechwood xylan thermobispora bispora 65.882 65.882 1 PMID:29936649 -1.1.1.203 d-glucurono-3,6-lactone penicillium camemberti 2.3 2.3 1 PMID:31756465 -1.1.1.203 d-mannuronate agrobacterium tumefaciens 92.0 88.5 2 PMID:25884328 -1.1.1.203 d-mannuronate fulvimarina pelagi 107.0 92.5 2 PMID:25884328 -1.1.1.203 d-mannuronate oceanicola granulosus 4.0 3.7 2 PMID:25884328 -1.1.1.203 d-mannuronate pseudomonas syringae pv. tomato 7.0 6.7 2 PMID:25884328 -1.1.1.203 d-mannuronate streptomyces viridochromogenes 9.0 8.5 2 PMID:25884328 -1.1.1.203 l-galactonate penicillium camemberti 0.75 0.75 1 PMID:31756465 -1.1.1.203 l-galactono-1,4-lactone penicillium camemberti 0.41 0.41 1 PMID:31756465 -1.1.1.203 l-gulonic acid penicillium camemberti 0.97 0.97 1 PMID:31756465 -1.1.1.203 l-gulono-1,4-lactone penicillium camemberti 0.41 0.41 1 PMID:31756465 -1.1.1.203 nad+ agrobacterium tumefaciens 144.0 144.0 1 PMID:25884328 -1.1.1.203 nad+ fulvimarina pelagi 113.0 113.0 1 PMID:25884328 -1.1.1.203 nad+ oceanicola granulosus 7.0 7.0 1 PMID:25884328 -1.1.1.203 nad+ pseudomonas syringae pv. tomato 215.0 215.0 1 PMID:25884328 -1.1.1.203 nad+ streptomyces viridochromogenes 62.0 62.0 1 PMID:25884328 -1.1.1.203 nad+ thermobispora bispora 74.667 74.667 1 PMID:29936649 -1.1.1.203 nadh penicillium camemberti 7.4 7.4 1 PMID:31756465 -1.1.1.203 nadph penicillium camemberti 9.6 9.6 1 PMID:31756465 -1.1.1.205 3-acetylpyridine adenine dinucleotide cryptosporidium parvum 3.0 1.58 2 PMID:21870820 -1.1.1.205 acetylpyridine adenine dinucleotide cryptosporidium parvum 3.0 3.0 1 PMID:18642884 -1.1.1.205 imp aspergillus nidulans 1.9 1.9 1 PMID:31675145 -1.1.1.205 imp bacillus amyloliquefaciens 5.1 5.1 1 PMID:26019494 -1.1.1.205 imp bacillus anthracis 5.3 4.15 2 PMID:25572472;PMID:30746940 -1.1.1.205 imp campylobacter jejuni 2.2 2.2 2 PMID:25572472;PMID:30746940 -1.1.1.205 imp clostridium perfringens 2.9 2.9 1 PMID:25572472 -1.1.1.205 imp cryptosporidium parvum 3.2 3.2 1 PMID:30746940 -1.1.1.205 imp eremothecium gossypii 2.46 2.46 1 PMID:26150243 -1.1.1.205 imp homo sapiens 0.22 0.03 3 PMID:30746940;PMID:7763314 -1.1.1.205 imp mycobacterium tuberculosis 0.53 0.53 1 PMID:26440283 -1.1.1.205 imp penicillium brevicompactum 2.7 2.7 1 PMID:31675145 -1.1.1.205 imp streptococcus pyogenes 0.4 0.4 1 PMID:10200156 -1.1.1.205 imp tritrichomonas foetus 0.7 0.7 1 PMID:30746940 -1.1.1.205 imp vibrio cholerae serotype o1 2.1 2.1 1 PMID:25572472 -1.1.1.205 inosine 5'-diphosphate bacillus anthracis 1.4 1.4 1 PMID:22788966 -1.1.1.205 inosine 5'-diphosphate trypanosoma brucei 0.28 0.28 1 PMID:23369253 -1.1.1.205 inosine 5'-phosphate borreliella burgdorferi 2.6 2.6 1 PMID:18990827 -1.1.1.205 inosine 5'-phosphate cryptosporidium parvum 3.3 3.3 1 PMID:18990827 -1.1.1.205 inosine 5'-phosphate escherichia coli 13.0 13.0 1 PMID:18990827 -1.1.1.205 inosine 5'-phosphate homo sapiens 1.8 0.855 6 PMID:17496727;PMID:18295591;PMID:18990827 -1.1.1.205 inosine 5'-phosphate mycobacterium tuberculosis 0.53 0.53 1 PMID:20491506 -1.1.1.205 inosine 5'-phosphate streptococcus pyogenes 24.0 24.0 1 PMID:18990827 -1.1.1.205 inosine 5'-phosphate toxoplasma gondii 0.98 0.98 1 PMID:15917510 -1.1.1.205 inosine 5'-phosphate tritrichomonas suis 1.9 1.9 4 PMID:12403633;PMID:18990827;PMID:21062060 -1.1.1.205 nad+ aspergillus nidulans 1.9 1.9 1 PMID:31675145 -1.1.1.205 nad+ bacillus anthracis 3.0 3.0 1 PMID:30746940 -1.1.1.205 nad+ borreliella burgdorferi 0.0433 0.0433 1 PMID:9268334 -1.1.1.205 nad+ campylobacter jejuni 2.2 2.2 1 PMID:30746940 -1.1.1.205 nad+ cryptosporidium parvum 3.2 2.6 5 PMID:18642884;PMID:21870820;PMID:30746940 -1.1.1.205 nad+ homo sapiens 1.2 0.22 5 PMID:15882147;PMID:18642884;PMID:30746940;PMID:7903306 -1.1.1.205 nad+ mycobacterium tuberculosis 3.1 1.815 2 PMID:26440283 -1.1.1.205 nad+ penicillium brevicompactum 2.7 2.7 1 PMID:31675145 -1.1.1.205 nad+ toxoplasma gondii 0.98 0.98 1 PMID:15917510 -1.1.1.205 nad+ tritrichomonas foetus 0.7 0.7 1 PMID:30746940 -1.1.1.205 nad+ tritrichomonas suis 1.9 1.65 2 PMID:12403633 -1.1.1.206 3-methylcyclohexanone withania somnifera 8.97 8.97 1 PMID:24086372 -1.1.1.206 3-quinuclidinone brugmansia arborea 0.54 0.54 1 PMID:26988730 -1.1.1.206 4-methylcyclohexanone brugmansia arborea 4.67 4.67 1 PMID:26988730 -1.1.1.206 n-methylpiperidine withania somnifera 9.23 9.23 1 PMID:24086372 -1.1.1.206 nadp+ withania coagulans 2.94 2.94 2 PMID:23266822 -1.1.1.206 nadp+ withania somnifera 0.54 0.54 1 PMID:24086372 -1.1.1.206 nadph withania coagulans 6.76 6.76 2 PMID:23266822 -1.1.1.206 nadph withania somnifera 33.34 33.34 1 PMID:24086372 -1.1.1.206 tropine brugmansia arborea 5.69 5.69 1 PMID:26988730 -1.1.1.206 tropine datura stramonium 3.3 3.3 1 PMID:26988730 -1.1.1.206 tropine withania coagulans 1.87 1.87 2 PMID:23266822 -1.1.1.206 tropine withania somnifera 1.67 1.67 1 PMID:24086372 -1.1.1.206 tropinone anisodus luridus 0.98 0.98 1 PMID:29085381 -1.1.1.206 tropinone brugmansia arborea 2.93 2.93 1 PMID:26988730 -1.1.1.206 tropinone datura stramonium 25.6 14.0 2 PMID:16426652;PMID:26988730 -1.1.1.206 tropinone przewalskia tangutica 42.26 32.31 2 PMID:31051047 -1.1.1.206 tropinone withania coagulans 16.74 16.74 2 PMID:23266822 -1.1.1.206 tropinone withania somnifera 9.51 9.51 1 PMID:24086372 -1.1.1.207 (-)-menthol mentha arvensis 63.33 23.2 3 PMID:28188954 -1.1.1.207 (-)-menthol mentha x piperita 18.6 17.8 3 PMID:28188954 -1.1.1.207 (-)-menthone mentha arvensis 95.9 88.5 3 PMID:28188954 -1.1.1.207 (-)-menthone mentha x piperita 2588.0 123.89999999999999 4 PMID:15728344;PMID:28188954 -1.1.1.207 (2r,5r)-isomenthone mentha x piperita 2.0 2.0 1 PMID:26017480 -1.1.1.207 (2s,5r)-menthone mentha x piperita 1.63 1.63 1 PMID:26017480 -1.1.1.207 nadph mentha x piperita 0.6 0.6 1 PMID:15728344 -1.1.1.208 (+)-neomenthol artemisia annua 0.91 0.91 1 PMID:20483909 -1.1.1.208 (-)-menthone artemisia annua 0.6 0.6 1 PMID:20483909 -1.1.1.208 (-)-menthone mentha arvensis 88.5 67.65 2 PMID:28188954 -1.1.1.208 (-)-menthone mentha x piperita 2588.0 89.6 3 PMID:15728344;PMID:28188954 -1.1.1.208 (2r,5r)-isomenthone mentha x piperita 0.2 0.2 1 PMID:26017480 -1.1.1.208 (2s,5r)-menthone mentha x piperita 0.96 0.96 1 PMID:26017480 -1.1.1.208 nadph mentha x piperita 0.06 0.06 1 PMID:15728344 -1.1.1.209 (2z)-2-(5-hydroxy-4,6-dimethyl-2-oxo-1,2-dihydro-3h-indol-3-ylidene)-n,n-di(prop-2-en-1-yl)hydrazinecarbothioamide homo sapiens 0.00617 0.00617 1 PMID:9415401 -1.1.1.209 4-androstene-3,17-dione mus musculus 0.167 0.167 2 PMID:19237748;PMID:20124700 -1.1.1.209 5alpha-androstan-17alpha-ol-3-one mus musculus 0.167 0.167 2 PMID:19237748;PMID:20124700 -1.1.1.209 5alpha-androstan-17beta-ol-3-one mus musculus 0.167 0.167 1 PMID:20124700 -1.1.1.209 5alpha-androstan-3alpha-ol-17-one mus musculus 0.073 0.073 2 PMID:19237748;PMID:20124700 -1.1.1.209 5alpha-androstan-3beta,17beta-diol mus musculus 0.167 0.167 1 PMID:20124700 -1.1.1.209 5alpha-dihydrotestosterone homo sapiens 0.003 0.003 1 PMID:9415401 -1.1.1.209 5alpha-pregnane-3alpha,20alpha-diol mus musculus 0.105 0.105 1 PMID:19237748 -1.1.1.209 5beta-androstan-17alpha-ol-3-one mus musculus 0.14 0.14 1 PMID:19237748 -1.1.1.209 5beta-pregnane-20alpha-ol-3-one mus musculus 0.383 0.383 1 PMID:20124700 -1.1.1.209 5beta-pregnane-3,20-dione mus musculus 0.4 0.4 1 PMID:20124700 -1.1.1.209 5beta-pregnane-3alpha,20alpha-diol mus musculus 0.217 0.21685 2 PMID:19237748;PMID:20124700 -1.1.1.209 androsterone homo sapiens 0.000367 0.000367 1 PMID:9415401 -1.1.1.209 epitestosterone mus musculus 0.3 0.3 2 PMID:19237748;PMID:20124700 -1.1.1.209 lithocholic acid mus musculus 0.047 0.047 1 PMID:20124700 -1.1.1.209 testosterone homo sapiens 0.0009 0.0009 1 PMID:9415401 -1.1.1.21 (1s)-camphorquinone rattus norvegicus 0.333 0.333 1 PMID:18845131 -1.1.1.21 (s)-1-indanol rattus norvegicus 0.007 0.007 1 PMID:18845131 -1.1.1.21 (s)-1-tetralol rattus norvegicus 0.003 0.003 1 PMID:18845131 -1.1.1.21 1-butanal homo sapiens 1.3 1.3 1 PMID:19464995 -1.1.1.21 1-butanal rattus norvegicus 0.67 0.67 1 PMID:18845131 -1.1.1.21 1-butanol rattus norvegicus 0.137 0.137 1 PMID:18845131 -1.1.1.21 1-decanal rattus norvegicus 0.35 0.35 1 PMID:18845131 -1.1.1.21 1-decanol homo sapiens 0.05 0.05 1 PMID:19464995 -1.1.1.21 1-decanol rattus norvegicus 0.023 0.023 1 PMID:18845131 -1.1.1.21 1-dodecanal homo sapiens 1.25 1.25 1 PMID:19464995 -1.1.1.21 1-heptanal homo sapiens 2.0 2.0 1 PMID:19464995 -1.1.1.21 1-hexanal homo sapiens 2.37 2.37 1 PMID:19464995 -1.1.1.21 1-hexanal rattus norvegicus 0.75 0.75 1 PMID:18845131 -1.1.1.21 1-hexanol homo sapiens 0.158 0.158 1 PMID:19464995 -1.1.1.21 1-hexanol rattus norvegicus 0.068 0.068 1 PMID:18845131 -1.1.1.21 1-nonanal homo sapiens 1.38 1.38 1 PMID:19464995 -1.1.1.21 1-nonanal rattus norvegicus 0.57 0.57 1 PMID:18845131 -1.1.1.21 1-nonanol homo sapiens 0.065 0.065 1 PMID:19464995 -1.1.1.21 1-nonanol rattus norvegicus 0.062 0.062 1 PMID:18845131 -1.1.1.21 1-octanal homo sapiens 1.37 1.37 1 PMID:19464995 -1.1.1.21 1-octanal rattus norvegicus 0.7 0.7 1 PMID:18845131 -1.1.1.21 1-palmitoyl-2-(5-oxovaleryl)sn-glycero-3-phosphocholine homo sapiens 0.61 0.61 1 PMID:15465833 -1.1.1.21 1-propanal rattus norvegicus 0.13 0.13 1 PMID:18845131 -1.1.1.21 1-tetradecanol homo sapiens 0.017 0.017 1 PMID:19464995 -1.1.1.21 16-ketoestrone rattus norvegicus 0.183 0.183 1 PMID:18845131 -1.1.1.21 2,3-butanedione rattus norvegicus 0.333 0.333 1 PMID:18845131 -1.1.1.21 2,3-heptanedione rattus norvegicus 0.6 0.6 1 PMID:18845131 -1.1.1.21 2,3-hexanedione homo sapiens 1.32 1.32 1 PMID:19464995 -1.1.1.21 2,3-hexanedione rattus norvegicus 0.25 0.25 1 PMID:18845131 -1.1.1.21 2,3-pentanedione rattus norvegicus 0.383 0.383 1 PMID:18845131 -1.1.1.21 2,4-decadienal rattus norvegicus 0.2 0.2 1 PMID:18845131 -1.1.1.21 2,4-nonadienal rattus norvegicus 0.2 0.2 1 PMID:18845131 -1.1.1.21 2-decenal rattus norvegicus 0.145 0.145 1 PMID:18845131 -1.1.1.21 2-deoxy-2-fluoro-galactose yamadazyma tenuis 0.183 0.183 1 PMID:11306077 -1.1.1.21 2-hexenal rattus norvegicus 0.67 0.67 1 PMID:18845131 -1.1.1.21 2-nonenal rattus norvegicus 0.155 0.155 1 PMID:18845131 -1.1.1.21 2-phenyl-1-propanol rattus norvegicus 0.012 0.012 1 PMID:18845131 -1.1.1.21 2-phenyl-2-propenal rattus norvegicus 0.43 0.43 1 PMID:18845131 -1.1.1.21 20alpha-hydroxyprogesterone homo sapiens 0.004 0.004 1 PMID:19464995 -1.1.1.21 20alpha-isocorticosterone homo sapiens 0.64 0.64 1 PMID:6814912 -1.1.1.21 21-dehydrocortisol homo sapiens 0.48 0.48 1 PMID:19464995 -1.1.1.21 21-dehydrocortisol rattus norvegicus 0.2 0.2 1 PMID:18845131 -1.1.1.21 3,4-hexanedione rattus norvegicus 0.233 0.233 1 PMID:18845131 -1.1.1.21 3-deoxyglucosone homo sapiens 0.75 0.75 1 PMID:19464995 -1.1.1.21 3-deoxyglucosone rattus norvegicus 0.2 0.2 1 PMID:18845131 -1.1.1.21 3-nitrobenzaldehyde debaryomyces nepalensis 40.0 40.0 1 * -1.1.1.21 4-hydroxynonenal rattus norvegicus 0.183 0.183 1 PMID:18845131 -1.1.1.21 4-nitrobenzaldehyde rattus norvegicus 0.57 0.57 1 PMID:18845131 -1.1.1.21 5-pregnene-3beta,20alpha-diol homo sapiens 0.006 0.006 1 PMID:19464995 -1.1.1.21 5alpha-pregnan-20alpha-ol-3-one homo sapiens 0.008 0.008 1 PMID:19464995 -1.1.1.21 5alpha-pregnane-3beta,20alpha-diol homo sapiens 0.012 0.012 1 PMID:19464995 -1.1.1.21 acetaldehyde escherichia coli 27.6 27.6 1 PMID:19609521 -1.1.1.21 acrolein rattus norvegicus 0.27 0.27 1 PMID:18845131 -1.1.1.21 acrolein yamadazyma tenuis 2.4 2.4 1 PMID:11306077 -1.1.1.21 benzaldehyde debaryomyces nepalensis 11.0 11.0 1 * -1.1.1.21 benzaldehyde homo sapiens 1.73 1.73 1 PMID:19464995 -1.1.1.21 benzaldehyde rattus norvegicus 0.42 0.42 1 PMID:18845131 -1.1.1.21 benzyl alcohol homo sapiens 0.167 0.167 1 PMID:19464995 -1.1.1.21 benzyl alcohol rattus norvegicus 0.0383 0.0383 1 PMID:18845131 -1.1.1.21 d-arabinose debaryomyces nepalensis 163.0 163.0 1 * -1.1.1.21 d-galactose debaryomyces nepalensis 106.0 106.0 1 * -1.1.1.21 d-galactose homo sapiens 0.525 0.379 2 PMID:1901806;PMID:1905957 -1.1.1.21 d-galactose yamadazyma tenuis 1.1 1.1 1 PMID:11306077 -1.1.1.21 d-glucose bos taurus 29.0 29.0 1 PMID:25528584 -1.1.1.21 d-glucose homo sapiens 126.0 0.48 3 PMID:1901806;PMID:1905957;PMID:25528584 -1.1.1.21 d-glucuronate homo sapiens 2.3 1.359 2 PMID:1901806;PMID:1905957 -1.1.1.21 d-glyceraldehyde homo sapiens 0.55 0.55 1 PMID:6814912 -1.1.1.21 d-lactoaldehyde homo sapiens 1.87 1.87 1 PMID:19464995 -1.1.1.21 d-lactoaldehyde rattus norvegicus 0.283 0.283 1 PMID:18845131 -1.1.1.21 d-ribose debaryomyces nepalensis 92.0 92.0 1 * -1.1.1.21 d-xylose debaryomyces nepalensis 108.0 108.0 1 * -1.1.1.21 d-xylose homo sapiens 1.7 1.1675 2 PMID:1901806;PMID:1905957 -1.1.1.21 d-xylose yamadazyma tenuis 0.283 0.283 1 PMID:11306077 -1.1.1.21 dl-glyceraldehyde homo sapiens 0.76 0.5865 4 PMID:15769597;PMID:16226225;PMID:1901806;PMID:1905957 -1.1.1.21 dl-glyceraldehyde rattus norvegicus 0.583 0.583 1 PMID:18845131 -1.1.1.21 dl-glyceraldehyde xerophyta viscosa 5.8 5.8 1 PMID:24939578 -1.1.1.21 dl-glyceraldehyde yamadazyma tenuis 155.0 155.0 1 PMID:11306077 -1.1.1.21 geraniol homo sapiens 0.567 0.567 1 PMID:19464995 -1.1.1.21 geranylgeraniol homo sapiens 0.165 0.1215 2 PMID:19464995 -1.1.1.21 glycoaldehyde rattus norvegicus 0.2 0.2 1 PMID:18845131 -1.1.1.21 glycolaldehyde homo sapiens 0.58 0.58 1 PMID:19464995 -1.1.1.21 glyoxal debaryomyces nepalensis 41.0 41.0 1 * -1.1.1.21 glyoxal homo sapiens 1.12 1.12 1 PMID:19464995 -1.1.1.21 glyoxal rattus norvegicus 0.2 0.2 1 PMID:18845131 -1.1.1.21 isatin homo sapiens 1.12 1.12 1 PMID:19464995 -1.1.1.21 isatin rattus norvegicus 0.283 0.283 1 PMID:18845131 -1.1.1.21 isobutyraldehyde escherichia coli 1.8 1.8 1 PMID:19609521 -1.1.1.21 isocaproaldehyde homo sapiens 1.43 1.43 1 PMID:19464995 -1.1.1.21 isophthalaldehyde debaryomyces nepalensis 8.0 8.0 1 * -1.1.1.21 l-idose bos taurus 30.0 30.0 1 PMID:25528584 -1.1.1.21 l-idose homo sapiens 143.0 143.0 1 PMID:25528584 -1.1.1.21 methylglyoxal leishmania donovani 78.4 61.400000000000006 2 PMID:18983902 -1.1.1.21 methylglyoxal rattus norvegicus 0.43 0.43 1 PMID:18845131 -1.1.1.21 methylglyoxal xerophyta viscosa 14.5 14.5 1 PMID:24939578 -1.1.1.21 methylglyoxal yamadazyma tenuis 266.0 266.0 1 PMID:11306077 -1.1.1.21 nerol homo sapiens 0.117 0.117 1 PMID:19464995 -1.1.1.21 phenyl-1,2-propanedione rattus norvegicus 0.383 0.383 1 PMID:18845131 -1.1.1.21 phenylglyoxal homo sapiens 0.76 0.76 1 PMID:6814912 -1.1.1.21 phenylglyoxal rattus norvegicus 0.42 0.42 1 PMID:18845131 -1.1.1.21 propanal yamadazyma tenuis 13.0 13.0 1 PMID:11306077 -1.1.1.21 pyridine-3-aldehyde debaryomyces nepalensis 7.0 7.0 1 * -1.1.1.21 pyridine-3-aldehyde homo sapiens 2.5 2.5 1 PMID:19464995 -1.1.1.21 pyridine-3-aldehyde rattus norvegicus 0.52 0.52 1 PMID:18845131 -1.1.1.21 pyridine-3-methanol homo sapiens 0.042 0.042 1 PMID:19464995 -1.1.1.21 pyridine-3-methanol rattus norvegicus 0.002 0.002 1 PMID:18845131 -1.1.1.21 pyridine-4-aldehyde rattus norvegicus 0.63 0.63 1 PMID:18845131 -1.1.1.21 trans,trans-farnesol homo sapiens 0.5 0.3275 2 PMID:19464995 -1.1.1.21 trans-2-buten-1-al homo sapiens 0.78 0.78 1 PMID:19464995 -1.1.1.21 trans-2-decen-1-al homo sapiens 1.83 1.83 1 PMID:19464995 -1.1.1.21 trans-2-hexen-1-al homo sapiens 0.82 0.82 1 PMID:19464995 -1.1.1.21 trans-2-nonen-1-al homo sapiens 1.34 1.34 1 PMID:19464995 -1.1.1.213 (2z)-2-(5-hydroxy-4,6-dimethyl-2-oxo-1,2-dihydro-3h-indol-3-ylidene)-n,n-di(prop-2-en-1-yl)hydrazinecarbothioamide rattus norvegicus 0.85 0.61 2 PMID:15379543 -1.1.1.213 (5beta,20r)-20-hydroxypregnan-3-one rattus norvegicus 0.115 0.115 1 PMID:17475203 -1.1.1.213 3-oxo-deoxycholic acid eggerthella sp. cag:298 54.5 54.5 1 PMID:29330189 -1.1.1.213 3alpha-androstanediol homo sapiens 0.008 0.008 1 PMID:17059222 -1.1.1.213 3alpha-hydroxy-5alpha-androstan-17-one rattus norvegicus 1.25 1.19 2 PMID:9029723 -1.1.1.213 4-oxo-2-nonenal homo sapiens 0.148 0.148 1 PMID:23165153 -1.1.1.213 5alpha-androstan-17beta-ol-3-one mesocricetus auratus 0.35 0.35 1 PMID:2317205 -1.1.1.213 5alpha-androstan-3,17-dione mesocricetus auratus 0.567 0.567 1 PMID:2317205 -1.1.1.213 5alpha-androstan-3,17-dione rattus norvegicus 0.283 0.275 2 PMID:9029723 -1.1.1.213 5alpha-androstan-3alpha,17beta-diol mesocricetus auratus 1.33 1.33 1 PMID:2317205 -1.1.1.213 5alpha-androstan-3alpha-ol-17-one mesocricetus auratus 2.72 2.72 1 PMID:2317205 -1.1.1.213 5alpha-androstane-3,17-dione rattus norvegicus 0.42 0.42 1 PMID:17848571 -1.1.1.213 5alpha-dihydroprogesterone rattus norvegicus 0.43 0.365 2 PMID:15379543 -1.1.1.213 5alpha-dihydrotestosterone homo sapiens 1339.0 669.5165 2 PMID:15929998;PMID:17059222 -1.1.1.213 5alpha-pregnan-21-ol-3,20-one mesocricetus auratus 0.767 0.767 1 PMID:2317205 -1.1.1.213 5alpha-pregnan-3alpha,21-diol-20-one mesocricetus auratus 0.233 0.233 1 PMID:2317205 -1.1.1.213 5beta-androstan-3,17-dione mesocricetus auratus 0.45 0.45 1 PMID:2317205 -1.1.1.213 5beta-androstan-3alpha,17beta-diol mesocricetus auratus 1.2 1.2 1 PMID:2317205 -1.1.1.213 5beta-androstan-3alpha-ol-17-one mesocricetus auratus 1.33 1.33 1 PMID:2317205 -1.1.1.213 5beta-androstane-3,17-dione rattus norvegicus 0.047 0.047 1 PMID:17475203 -1.1.1.213 5beta-dihydrocortisone mesocricetus auratus 0.433 0.433 1 PMID:2317205 -1.1.1.213 5beta-pregnan-3,20-dione mesocricetus auratus 0.417 0.417 1 PMID:2317205 -1.1.1.213 5beta-pregnan-3alpha,21-diol-20-one mesocricetus auratus 0.633 0.633 1 PMID:2317205 -1.1.1.213 5beta-pregnan-3alpha-ol-20-one mesocricetus auratus 0.767 0.767 1 PMID:2317205 -1.1.1.213 5beta-pregnane-3,20-dione rattus norvegicus 0.105 0.105 1 PMID:17475203 -1.1.1.213 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one rattus norvegicus 0.1 0.1 1 PMID:17475203 -1.1.1.213 9,10-phenanthrenequinone rattus norvegicus 3.93 2.0565 2 PMID:17475203;PMID:8939970 -1.1.1.213 androsterone comamonas testosteroni 318.0 318.0 1 PMID:15572373 -1.1.1.213 androsterone rattus norvegicus 0.83 0.825 2 PMID:15134457;PMID:17848571 -1.1.1.213 dehydrolithocholic acid mesocricetus auratus 0.733 0.733 1 PMID:2317205 -1.1.1.213 dehydrolithocholic acid rattus norvegicus 0.022 0.022 1 PMID:17475203 -1.1.1.213 deoxycholic acid eggerthella sp. cag:298 55.9 55.9 1 PMID:29330189 -1.1.1.213 diacetyl rattus norvegicus 0.167 0.167 1 PMID:17475203 -1.1.1.213 glycochenodeoxycholic acid mesocricetus auratus 0.2 0.2 1 PMID:2317205 -1.1.1.213 glycolithocholic acid mesocricetus auratus 0.233 0.233 1 PMID:2317205 -1.1.1.213 isatin rattus norvegicus 0.283 0.283 1 PMID:17475203 -1.1.1.213 lithocholic acid mesocricetus auratus 0.217 0.217 1 PMID:2317205 -1.1.1.213 nad+ rattus norvegicus 1.43 1.2799999999999998 2 PMID:9029723 -1.1.1.213 nadh rattus norvegicus 0.367 0.32499999999999996 2 PMID:9029723 -1.1.1.214 2-dehydropantolactone candida dubliniensis 59.0 59.0 1 PMID:31000167 -1.1.1.215 2-oxo-d-gluconate gluconobacter oxydans 48.2 48.2 1 PMID:20676631 -1.1.1.215 2-oxo-l-gulonate aspergillus niger 21.4 21.4 1 PMID:28261181 -1.1.1.215 l-idonate aspergillus niger 1.1 1.1 1 PMID:28261181 -1.1.1.218 morphine oryctolagus cuniculus 0.49 0.49 1 PMID:23228597 -1.1.1.218 nad+ oryctolagus cuniculus 0.004 0.004 1 PMID:23228597 -1.1.1.218 trans-naphthalene dihydrodiol oryctolagus cuniculus 0.067 0.067 1 PMID:23228597 -1.1.1.219 (4s)-5,5,5-trifluoro-4-hydroxy-4-phenylpentan-2-one komagataella phaffii 44.5 44.5 1 PMID:27123855 -1.1.1.219 benzaldehyde komagataella phaffii 54.4 54.4 1 PMID:27123855 -1.1.1.219 dihydrokaempferol fragaria x ananassa 11.4 11.4 1 PMID:25393679 -1.1.1.219 dihydromyricetin fragaria x ananassa 11.2 11.2 1 PMID:25393679 -1.1.1.219 dihydroquercetin fragaria x ananassa 3.1 3.1 1 PMID:25393679 -1.1.1.219 nadph komagataella phaffii 58.4 58.4 1 PMID:27123855 -1.1.1.22 aldehyde intermediate streptococcus pyogenes 1.9 1.9 1 PMID:14686915 -1.1.1.22 nad+ burkholderia cenocepacia j2315 0.156 0.155 2 PMID:19383677 -1.1.1.22 nad+ burkholderia cepacia 6.7 6.7 1 PMID:21602353 -1.1.1.22 nad+ caenorhabditis elegans 1.7 1.7 1 PMID:31616809 -1.1.1.22 nad+ campylobacter jejuni subsp. jejuni 0.8 0.8 1 PMID:33621065 -1.1.1.22 nad+ escherichia coli 56.2 7.1 3 PMID:23792965 -1.1.1.22 nad+ homo sapiens 4.4 1.37 4 PMID:23106432;PMID:23363239;PMID:27966912;PMID:30457329 -1.1.1.22 nad+ pseudomonas aeruginosa 2.35 1.36 2 PMID:17442666 -1.1.1.22 nad+ sphingomonas elodea 7.6 7.6 1 PMID:17668199 -1.1.1.22 nad+ sphingomonas sanxanigenens 50.2 50.2 1 PMID:25842901 -1.1.1.22 udp homo sapiens 105.0 105.0 1 PMID:17927902 -1.1.1.22 udp-alpha-d-glucose burkholderia cepacia 6.9 6.9 1 PMID:21602353 -1.1.1.22 udp-alpha-d-glucose caenorhabditis elegans 1.23 1.23 1 PMID:31616809 -1.1.1.22 udp-alpha-d-glucose campylobacter jejuni subsp. jejuni 1.1 1.1 1 PMID:33621065 -1.1.1.22 udp-alpha-d-glucose homo sapiens 3.2 0.85 5 PMID:22123821;PMID:23106432;PMID:23363239;PMID:27966912;PMID:30457329 -1.1.1.22 udp-alpha-d-glucose sphingomonas sanxanigenens 57.9 57.9 1 PMID:25842901 -1.1.1.22 udp-glucose arabidopsis thaliana 2.53 1.92 3 PMID:18057039 -1.1.1.22 udp-glucose burkholderia cenocepacia j2315 0.133 0.13 2 PMID:19383677 -1.1.1.22 udp-glucose pseudomonas aeruginosa 0.81 0.525 2 PMID:17442666 -1.1.1.22 udp-glucose sphingomonas elodea 8.73 8.73 1 PMID:17668199 -1.1.1.22 udpglucose streptococcus pyogenes 0.117 0.117 1 PMID:9013585 -1.1.1.227 (-)-borneol lavandula x intermedia 0.0004 0.0004 1 PMID:23058847 -1.1.1.227 (-)-borneol pseudomonas monteilii 29.4 20.35 2 PMID:32732035 -1.1.1.227 (-)-borneol pseudomonas putida 0.97 0.97 1 PMID:33846823 -1.1.1.227 (-)-borneol pseudomonas sp. 0.53 0.53 1 PMID:27542933 -1.1.1.227 (-)-borneol pseudomonas sp. tcu-hl1 12.4 6.390000000000001 2 PMID:32738440 -1.1.1.23 l-histidinal salmonella enterica subsp. enterica serovar typhimurium 9.34 3.6 3 PMID:3894023;PMID:8188630 -1.1.1.23 l-histidinol brassica oleracea 35.0 18.05 2 PMID:8037463;PMID:8138543 -1.1.1.23 l-histidinol mycobacterium tuberculosis 1.45 1.436 3 PMID:21672513 -1.1.1.23 nad+ mycobacterium tuberculosis 1.361 1.134 3 * -1.1.1.236 nadph datura stramonium 71.4 71.4 1 PMID:12741812 -1.1.1.236 tropinone datura stramonium 71.4 37.065000000000005 2 PMID:12741812;PMID:16426652 -1.1.1.236 tropinone przewalskia tangutica 116.9 63.580000000000005 2 PMID:31051047 -1.1.1.237 3-(4-hydroxyphenyl)pyruvate arabidopsis thaliana 0.285 0.285 1 PMID:30233632 -1.1.1.237 4-hydroxyphenylpyruvate arabidopsis thaliana 0.28 0.201 2 PMID:30233632 -1.1.1.237 glyoxylate wickerhamia fluorescens 19.0 19.0 1 PMID:21672638 -1.1.1.237 hydroxyphenylpyruvate wickerhamia fluorescens 73.0 73.0 1 PMID:21672638 -1.1.1.237 hydroxypyruvate arabidopsis thaliana 0.052 0.052 1 PMID:30233632 -1.1.1.237 hydroxypyruvate wickerhamia fluorescens 9.1 9.1 1 PMID:21672638 -1.1.1.237 nadh wickerhamia fluorescens 31.0 31.0 1 PMID:21672638 -1.1.1.237 nadph wickerhamia fluorescens 121.0 121.0 1 PMID:21672638 -1.1.1.237 phenylpyruvate arabidopsis thaliana 0.611 0.61 3 PMID:30233632 -1.1.1.237 phenylpyruvate wickerhamia fluorescens 150.0 150.0 1 PMID:21672638 -1.1.1.239 (r)-1,2,3,4-tetrahydro-1-naphthol mesocricetus auratus 0.0075 0.0075 1 PMID:26002966 -1.1.1.239 (s)-1,2,3,4-tetrahydro-1-naphthol mesocricetus auratus 0.105 0.105 1 PMID:26002966 -1.1.1.239 (s)-1,2,3,4-tetrahydro-1-naphthol oryctolagus cuniculus 0.367 0.1 3 PMID:23228597 -1.1.1.239 (s)-1-indanol mesocricetus auratus 0.1 0.1 1 PMID:26002966 -1.1.1.239 (s)-1-indanol oryctolagus cuniculus 0.4 0.13 3 PMID:23228597 -1.1.1.239 (s)-camphorquinone oryctolagus cuniculus 0.98 0.183 3 PMID:23228597 -1.1.1.239 1-acenaphthenol mesocricetus auratus 0.283 0.283 1 PMID:26002966 -1.1.1.239 1-phenyl-1,2-propanedione oryctolagus cuniculus 0.45 0.2 3 PMID:23228597 -1.1.1.239 16-oxoestrone oryctolagus cuniculus 0.867 0.267 3 PMID:23228597 -1.1.1.239 17beta-estradiol oryctolagus cuniculus 0.0217 0.014 2 PMID:23228597 -1.1.1.239 2,3-butanedione oryctolagus cuniculus 0.55 0.233 3 PMID:23228597 -1.1.1.239 2-cyclohexen-1-ol mesocricetus auratus 0.028 0.028 1 PMID:26002966 -1.1.1.239 2-cyclohexen-1-ol oryctolagus cuniculus 0.16 0.072 3 PMID:23228597 -1.1.1.239 4-oxo-2-nonenal homo sapiens 0.148 0.148 1 PMID:23165153 -1.1.1.239 4-pregnen-3alpha-ol-20-one oryctolagus cuniculus 0.012 0.0032 3 PMID:23228597 -1.1.1.239 5alpha-androstan-17beta-ol-3-one oryctolagus cuniculus 0.065 0.0103 3 PMID:23228597 -1.1.1.239 5alpha-androstan-3alpha,17beta-diol mesocricetus auratus 0.45 0.45 1 PMID:2317205 -1.1.1.239 5alpha-androstan-3alpha-ol-17-one oryctolagus cuniculus 0.058 0.03065 2 PMID:23228597 -1.1.1.239 5alpha-androstane-3alpha,17beta-diol oryctolagus cuniculus 0.055 0.02885 2 PMID:23228597 -1.1.1.239 5alpha-pregnan-3alpha,21-diol-20-one mesocricetus auratus 0.267 0.267 1 PMID:2317205 -1.1.1.239 5alpha-pregnan-3alpha-ol-20-one oryctolagus cuniculus 0.0072 0.0042 2 PMID:23228597 -1.1.1.239 5beta-androstan-17beta-ol-3-one mesocricetus auratus 0.367 0.367 1 PMID:2317205 -1.1.1.239 5beta-androstan-17beta-ol-3-one oryctolagus cuniculus 0.0167 0.0032 3 PMID:23228597 -1.1.1.239 5beta-androstan-3,17-dione mesocricetus auratus 0.167 0.167 1 PMID:2317205 -1.1.1.239 5beta-androstan-3alpha,17beta-diol mesocricetus auratus 0.85 0.85 1 PMID:2317205 -1.1.1.239 5beta-androstan-3alpha-ol-17-one oryctolagus cuniculus 0.052 0.02715 2 PMID:23228597 -1.1.1.239 5beta-androstane-3alpha,17beta-diol oryctolagus cuniculus 0.0122 0.0081 2 PMID:23228597 -1.1.1.239 5beta-pregnan-3,20-dione mesocricetus auratus 0.158 0.158 1 PMID:2317205 -1.1.1.239 5beta-pregnan-3alpha,21-diol-20-one mesocricetus auratus 0.367 0.367 1 PMID:2317205 -1.1.1.239 5beta-pregnan-3alpha-ol-20-one mesocricetus auratus 0.233 0.233 1 PMID:2317205 -1.1.1.239 5beta-pregnan-3alpha-ol-20-one oryctolagus cuniculus 0.023 0.0074 3 PMID:23228597 -1.1.1.239 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one oryctolagus cuniculus 0.108 0.108 3 PMID:23228597 -1.1.1.239 9,10-phenanthrenequinone oryctolagus cuniculus 0.617 0.233 3 PMID:23228597 -1.1.1.239 alpha-3-hydroxyhexobarbital mesocricetus auratus 0.04 0.04 1 PMID:26002966 -1.1.1.239 alpha-tetralone oryctolagus cuniculus 0.2 0.07 3 PMID:23228597 -1.1.1.239 benzene dihydrodiol oryctolagus cuniculus 0.29 0.127 3 PMID:23228597 -1.1.1.239 beta-3-hydroxyhexobarbital mesocricetus auratus 0.0967 0.0967 1 PMID:26002966 -1.1.1.239 beta-ionol mesocricetus auratus 0.053 0.053 1 PMID:26002966 -1.1.1.239 beta-ionol oryctolagus cuniculus 0.028 0.017750000000000002 2 PMID:23228597 -1.1.1.239 cis-benzene dihydrodiol mesocricetus auratus 0.032 0.032 1 PMID:26002966 -1.1.1.239 estrone homo sapiens 0.0011 0.0011 1 PMID:20036328 -1.1.1.239 farnesol mesocricetus auratus 0.0045 0.0045 1 PMID:26002966 -1.1.1.239 farnesol oryctolagus cuniculus 0.027 0.01625 2 PMID:23228597 -1.1.1.239 geraniol mesocricetus auratus 0.0153 0.0153 1 PMID:26002966 -1.1.1.239 geraniol oryctolagus cuniculus 0.028 0.019 3 PMID:23228597 -1.1.1.239 geranylgeraniol mesocricetus auratus 0.038 0.038 1 PMID:26002966 -1.1.1.239 geranylgeraniol oryctolagus cuniculus 0.0127 0.00675 2 PMID:23228597 -1.1.1.239 glycochenodeoxycholic acid mesocricetus auratus 0.02 0.02 1 PMID:2317205 -1.1.1.239 glycolithocholic acid mesocricetus auratus 0.25 0.25 1 PMID:2317205 -1.1.1.239 isatin oryctolagus cuniculus 0.65 0.217 3 PMID:23228597 -1.1.1.239 lithocholic acid mesocricetus auratus 0.05 0.05 1 PMID:2317205 -1.1.1.239 lithocholic acid oryctolagus cuniculus 0.018 0.015 3 PMID:23228597 -1.1.1.239 morphine oryctolagus cuniculus 0.49 0.49 1 PMID:23228597 -1.1.1.239 nad+ mesocricetus auratus 0.025 0.025 1 PMID:26002966 -1.1.1.239 nad+ oryctolagus cuniculus 0.283 0.1 3 PMID:23228597 -1.1.1.239 nadh mesocricetus auratus 0.167 0.167 1 PMID:26002966 -1.1.1.239 nadh oryctolagus cuniculus 0.683 0.217 3 PMID:23228597 -1.1.1.239 nadp+ mesocricetus auratus 0.0917 0.0917 1 PMID:26002966 -1.1.1.239 naphthalene dihydrodiol oryctolagus cuniculus 0.067 0.067 1 PMID:23228597 -1.1.1.239 nerol mesocricetus auratus 0.115 0.115 1 PMID:26002966 -1.1.1.239 pyridine-3-aldehyde oryctolagus cuniculus 0.2 0.085 3 PMID:23228597 -1.1.1.239 testosterone mesocricetus auratus 0.417 0.417 1 PMID:2317205 -1.1.1.239 testosterone oryctolagus cuniculus 0.098 0.0082 3 PMID:23228597 -1.1.1.239 trans-benzene dihydrodiol mesocricetus auratus 0.045 0.045 1 PMID:26002966 -1.1.1.24 3-dehydroquinate eucalyptus camaldulensis 281.0 281.0 1 PMID:33346890 -1.1.1.24 l-quinate corynebacterium glutamicum 104.9 61.9 3 PMID:18566515;PMID:23929881 -1.1.1.24 l-quinate eucalyptus camaldulensis 127.0 127.0 1 PMID:33346890 -1.1.1.24 nad+ corynebacterium glutamicum 223.1 133.45000000000002 4 PMID:23929881 -1.1.1.24 nad+ eucalyptus camaldulensis 139.0 139.0 1 PMID:33346890 -1.1.1.24 nadh eucalyptus camaldulensis 298.0 298.0 1 PMID:33346890 -1.1.1.24 shikimate corynebacterium glutamicum 214.1 85.2 3 PMID:18566515;PMID:23929881 -1.1.1.240 n-acetyl-d-galactosamine pseudomonas sp. 932.0 932.0 1 * -1.1.1.240 n-acetyl-d-glucosamine pseudomonas sp. 655.0 655.0 1 * -1.1.1.244 butanol lysinibacillus xylanilyticus 0.52 0.52 1 PMID:32117944 -1.1.1.244 ethanol lysinibacillus xylanilyticus 0.46 0.46 1 PMID:32117944 -1.1.1.244 methanol cupriavidus necator 0.22 0.22 1 PMID:26846745 -1.1.1.244 methanol lysinibacillus xylanilyticus 0.21 0.12165 2 PMID:32117944;PMID:33540582 -1.1.1.244 n-butanol cupriavidus necator 6.5 6.5 1 PMID:26846745 -1.1.1.244 n-propanol lysinibacillus xylanilyticus 0.55 0.55 1 PMID:32117944 -1.1.1.244 nad+ cupriavidus necator 0.24 0.24 1 PMID:26846745 -1.1.1.244 nad+ lysinibacillus xylanilyticus 0.37 0.37 1 PMID:32117944 -1.1.1.247 codeine papaver somniferum 0.027 0.020999999999999998 2 PMID:29779229 -1.1.1.247 codeinone papaver somniferum 0.04 0.0315 2 PMID:29779229 -1.1.1.247 nadp+ papaver somniferum 0.067 0.0555 2 PMID:29779229 -1.1.1.247 nadph papaver somniferum 0.06 0.0525 2 PMID:29779229 -1.1.1.248 (7s)-salutaridinol papaver bracteatum 21.6 21.6 1 PMID:17337529 -1.1.1.248 nadh papaver bracteatum 3.7 3.7 1 PMID:17337529 -1.1.1.248 nadp+ papaver bracteatum 21.9 21.9 1 PMID:17337529 -1.1.1.248 nadph papaver bracteatum 2.1 2.1 1 PMID:17337529 -1.1.1.248 salutaridine papaver bracteatum 2.3 2.3 1 PMID:17337529 -1.1.1.248 salutaridine papaver somniferum 1.306 1.306 1 PMID:19648114 -1.1.1.25 3-dehydroquinate corynebacterium glutamicum 114.0 57.18 2 PMID:23306642 -1.1.1.25 3-dehydroshikimate camellia sinensis 0.405 0.168 3 PMID:31681371 -1.1.1.25 3-dehydroshikimate corynebacterium glutamicum 329.0 118.0 3 PMID:23306642;PMID:25524738 -1.1.1.25 3-dehydroshikimate eucalyptus camaldulensis 307.0 47.0 11 PMID:33346890 -1.1.1.25 3-dehydroshikimate mycobacterium tuberculosis 50.0 49.0 4 PMID:16298142;PMID:17178095;PMID:19917104;PMID:25524738 -1.1.1.25 3-dehydroshikimate vitis vinifera 95.85 52.235 2 PMID:27241494 -1.1.1.25 nad+ helicobacter pylori 5.2 5.2 1 PMID:16972983 -1.1.1.25 nad+ pseudomonas putida 97.1 50.900000000000006 4 PMID:18669580 -1.1.1.25 nad+ pseudomonas putida kt2440 97.1 51.91 2 PMID:18669580 -1.1.1.25 nad+ staphylococcus epidermidis rp62a 87.0 87.0 1 PMID:19215302 -1.1.1.25 nadp+ aquifex aeolicus 55.5 55.5 1 PMID:25524738 -1.1.1.25 nadp+ arabidopsis thaliana 399.0 399.0 3 PMID:16922517;PMID:25524738 -1.1.1.25 nadp+ archaeoglobus fulgidus 390.0 390.0 1 PMID:25524738 -1.1.1.25 nadp+ camellia sinensis 0.117 0.043 3 PMID:31681371 -1.1.1.25 nadp+ escherichia coli 237.0 237.0 1 PMID:25524738 -1.1.1.25 nadp+ eucalyptus camaldulensis 792.0 135.0 6 PMID:33346890 -1.1.1.25 nadp+ helicobacter pylori 7.1 7.1 2 PMID:16972983;PMID:25524738 -1.1.1.25 nadp+ mycobacterium tuberculosis 399.0 202.45 4 PMID:16202245;PMID:16298142;PMID:25524738 -1.1.1.25 nadp+ pseudomonas putida 302.0 261.5 3 PMID:18669580;PMID:25524738 -1.1.1.25 nadp+ pseudomonas putida kt2440 261.5 5.3 3 PMID:18669580 -1.1.1.25 nadp+ staphylococcus aureus 146.2 146.2 2 PMID:24727420;PMID:25524738 -1.1.1.25 nadp+ staphylococcus epidermidis 22.8 22.8 1 PMID:25524738 -1.1.1.25 nadp+ toxoplasma gondii 2.77 2.77 1 PMID:25524738 -1.1.1.25 nadp+ vitis vinifera 239.0 28.89 5 PMID:27241494 -1.1.1.25 nadph camellia sinensis 0.202 0.052 3 PMID:31681371 -1.1.1.25 nadph eucalyptus camaldulensis 389.0 74.1 6 PMID:33346890 -1.1.1.25 nadph mycobacterium tuberculosis 50.0 45.0 3 PMID:16298142;PMID:19463851;PMID:25524738 -1.1.1.25 quinate corynebacterium glutamicum 61.9 61.9 1 PMID:18566515 -1.1.1.25 quinate pseudomonas putida 37.7 37.7 1 PMID:18669580 -1.1.1.25 quinate pseudomonas putida kt2440 0.16 0.16 1 PMID:18669580 -1.1.1.25 shikimate aquifex aeolicus 55.5 55.25 2 PMID:17649975;PMID:25524738 -1.1.1.25 shikimate arabidopsis thaliana 516.0 428.0 4 PMID:16922517;PMID:25524738;PMID:29890023 -1.1.1.25 shikimate aspergillus nidulans 1.5 1.5 1 PMID:25524738 -1.1.1.25 shikimate camellia sinensis 0.153 0.107 3 PMID:31681371 -1.1.1.25 shikimate corynebacterium glutamicum 234.0 159.6 4 PMID:18566515;PMID:23306642;PMID:25524738 -1.1.1.25 shikimate escherichia coli 237.0 213.5 2 PMID:25524738;PMID:28633311 -1.1.1.25 shikimate eucalyptus camaldulensis 755.0 146.0 6 PMID:33346890 -1.1.1.25 shikimate helicobacter pylori 7.7 7.7 2 PMID:16972983;PMID:25524738 -1.1.1.25 shikimate mycobacterium tuberculosis 399.0 203.6 4 PMID:16202245;PMID:16298142;PMID:25524738 -1.1.1.25 shikimate pseudomonas putida 307.0 43.45 6 PMID:18669580;PMID:25524738 -1.1.1.25 shikimate pseudomonas putida kt2440 266.2 18.5 4 PMID:18669580 -1.1.1.25 shikimate staphylococcus aureus 135.8 135.8 2 PMID:24727420;PMID:25524738 -1.1.1.25 shikimate staphylococcus epidermidis 22.8 22.8 1 PMID:25524738 -1.1.1.25 shikimate staphylococcus epidermidis rp62a 22.8 22.8 1 PMID:19215302 -1.1.1.25 shikimate toxoplasma gondii 2.78 2.78 2 PMID:24731949;PMID:25524738 -1.1.1.25 shikimate vitis vinifera 94.55 11.72 5 PMID:27241494 -1.1.1.250 d-arabitol thermotoga maritima 18.7 14.85 2 PMID:21347726 -1.1.1.250 d-ribulose thermotoga maritima 193.2 179.39999999999998 2 PMID:21347726 -1.1.1.250 d-xylitol thermotoga maritima 16.6 13.9 2 PMID:21347726 -1.1.1.252 2,3-dihydro-2,5-dihydroxy-4h-benzopyran-4-one pyricularia grisea 14.0 14.0 1 PMID:9048570;PMID:9466791 -1.1.1.252 phenanthrenequinone pyricularia grisea 13.0 13.0 1 PMID:9048570 -1.1.1.252 scytalone pyricularia grisea 0.38 0.38 1 PMID:9048570 -1.1.1.26 2-oxobutyrate rhizobium etli 0.5 0.5 1 PMID:17693143 -1.1.1.26 glyoxylate arabidopsis thaliana 68.0 13.0 3 PMID:32156771 -1.1.1.26 glyoxylate rhizobium etli 1.35 1.35 1 PMID:17693143 -1.1.1.26 hydroxypyruvate rhizobium etli 0.25 0.25 1 PMID:17693143 -1.1.1.26 nadh arabidopsis thaliana 62.0 62.0 1 PMID:32156771 -1.1.1.26 nadph arabidopsis thaliana 8.1 4.33 2 PMID:32156771 -1.1.1.26 phenylpyruvate rhizobium etli 0.37 0.37 1 PMID:17693143 -1.1.1.261 dihydroxyacetone phosphate aeropyrum pernix 4.998 2.95 4 PMID:11846799;PMID:15876564 -1.1.1.261 dihydroxyacetone phosphate methanocaldococcus jannaschii 2.78 2.11 4 PMID:26175150 -1.1.1.261 dihydroxyacetone phosphate pyrobaculum calidifontis 10.4 5.3500000000000005 2 PMID:27616573 -1.1.1.261 nad+ aeropyrum pernix 0.09 0.09 1 PMID:11846799 -1.1.1.261 nadh aeropyrum pernix 2.4 2.4 1 PMID:11846799 -1.1.1.261 nadh methanocaldococcus jannaschii 3.33 3.33 2 PMID:26175150 -1.1.1.261 nadh pyrobaculum calidifontis 11.0 11.0 1 PMID:27616573 -1.1.1.261 nadph aeropyrum pernix 0.044 0.044 1 PMID:11846799 -1.1.1.261 nadph methanocaldococcus jannaschii 3.23 3.23 2 PMID:26175150 -1.1.1.261 nadph pyrobaculum calidifontis 0.26 0.26 1 PMID:27616573 -1.1.1.261 sn-glycerol-1-phosphate aeropyrum pernix 0.09 0.09 1 PMID:11846799 -1.1.1.262 4-(phosphohydroxy)-l-threonine escherichia coli 1.4 1.4 1 PMID:10225425 -1.1.1.263 1,5-anhydro-d-fructose ensifer adhaerens 1300.0 251.35 4 PMID:16461673;PMID:16906761 -1.1.1.263 1,5-anhydro-d-fructose sus scrofa 8.7 8.7 1 PMID:9504428 -1.1.1.263 d-glucosone ensifer adhaerens 63.2 63.2 1 PMID:16461673 -1.1.1.264 5-dehydro-d-gluconate aspergillus niger 7.2 7.2 2 PMID:28261181 -1.1.1.264 l-idonate aspergillus niger 5.5 5.5 2 PMID:28261181 -1.1.1.265 2-methylbutanal saccharomyces cerevisiae 113.0 102.65 2 PMID:9327572 -1.1.1.265 3-methylbutanal saccharomyces cerevisiae 91.8 74.9 3 PMID:24879127;PMID:9327572 -1.1.1.265 acetaldehyde saccharomyces cerevisiae 313.14 159.37 2 PMID:32967812;PMID:9327572 -1.1.1.265 butanal saccharomyces cerevisiae 57.0 52.15 2 PMID:9327572 -1.1.1.265 furfural saccharomyces cerevisiae 36.9 36.9 1 PMID:32967812 -1.1.1.265 glycolaldehyde saccharomyces cerevisiae 15.44 15.44 1 PMID:32967812 -1.1.1.265 heptanal saccharomyces cerevisiae 101.0 86.95 2 PMID:9327572 -1.1.1.265 hexanal saccharomyces cerevisiae 71.1 60.599999999999994 2 PMID:9327572 -1.1.1.265 hexanol saccharomyces cerevisiae 2.55 2.55 1 PMID:9327572 -1.1.1.265 pentanal saccharomyces cerevisiae 81.6 69.1 2 PMID:9327572 -1.1.1.265 propanal saccharomyces cerevisiae 84.0 69.5 2 PMID:9327572 -1.1.1.265 trans-2-hexenol saccharomyces cerevisiae 14.0 14.0 1 PMID:9327572 -1.1.1.266 dtdp-4-keto-6-deoxy-d-glucose aggregatibacter actinomycetemcomitans 43.5 43.5 1 PMID:10358040 -1.1.1.267 1-deoxy-d-xylulose 5-phosphate arabidopsis thaliana 4.4 4.4 1 PMID:16972937 -1.1.1.267 1-deoxy-d-xylulose 5-phosphate escherichia coli 38.0 33.0 3 PMID:15760175;PMID:15938625;PMID:16292827 -1.1.1.267 1-deoxy-d-xylulose 5-phosphate francisella tularensis 2.0 2.0 1 PMID:20011597 -1.1.1.267 1-deoxy-d-xylulose 5-phosphate mycobacterium tuberculosis 5.3 5.25 3 PMID:16790937;PMID:22690952;PMID:23473304;PMID:24825256 -1.1.1.267 1-deoxy-d-xylulose 5-phosphate synechocystis sp. 17.0 17.0 1 PMID:16289362 -1.1.1.267 1-deoxy-d-xylulose 5-phosphate synthetic construct 16.1 13.7 3 PMID:19159292 -1.1.1.267 1-deoxy-d-xylulose 5-phosphate yersinia pestis 1.7 1.7 1 PMID:25171339 -1.1.1.267 1-deoxy-l-erythrulose mycobacterium tuberculosis 0.00155 0.001205 2 PMID:23473304 -1.1.1.267 1-fluoro-1-deoxy-d-xylulose 5-phosphate escherichia coli 37.0 37.0 1 PMID:15938625 -1.1.1.267 2-c-methyl-d-erythritol 4-phosphate arabidopsis thaliana 1.6 1.6 1 PMID:16972937 -1.1.1.267 2-c-methyl-d-erythritol 4-phosphate mycobacterium tuberculosis 0.95 0.95 1 PMID:22690952 -1.1.1.267 nadp+ arabidopsis thaliana 1.6 1.6 1 PMID:16972937 -1.1.1.267 nadp+ mycobacterium tuberculosis 0.95 0.95 1 PMID:22690952 -1.1.1.267 nadph arabidopsis thaliana 4.4 4.4 1 PMID:16972937 -1.1.1.267 nadph francisella tularensis 1.3 1.3 1 PMID:20011597 -1.1.1.267 nadph mycobacterium tuberculosis 5.3 5.275 2 PMID:16790937;PMID:22690952 -1.1.1.267 nadph thermotoga maritima 5.5 2.895 2 PMID:20353826 -1.1.1.267 nadph yersinia pestis 1.0 1.0 1 PMID:25171339 -1.1.1.268 (2r)-2-butanol xanthobacter autotrophicus 0.98 0.98 1 PMID:30592559 -1.1.1.268 (2r)-2-heptanol xanthobacter autotrophicus 1.8 1.8 1 PMID:30592559 -1.1.1.268 (2r)-2-hexanol xanthobacter autotrophicus 2.7 2.7 1 PMID:30592559 -1.1.1.268 (2r)-2-hydroxypropyl-com xanthobacter autotrophicus 26.8 26.8 1 PMID:30592559 -1.1.1.268 (2r)-2-octanol xanthobacter autotrophicus 1.7 1.7 1 PMID:30592559 -1.1.1.268 (2r)-2-pentanol xanthobacter autotrophicus 1.1 1.1 1 PMID:30592559 -1.1.1.268 (2s)-2-butanol xanthobacter autotrophicus 2.2 2.2 1 PMID:30592559 -1.1.1.268 (2s)-2-hydroxypropyl-com xanthobacter autotrophicus 0.044 0.044 1 PMID:30592559 -1.1.1.268 (2s)-2-pentanol xanthobacter autotrophicus 2.9 2.9 1 PMID:30592559 -1.1.1.268 (r)-2-butanol xanthobacter autotrophicus 1.9 1.44 2 PMID:15157110;PMID:20302306 -1.1.1.268 (r)-2-heptanol xanthobacter autotrophicus 1.8 1.8 1 PMID:15157110 -1.1.1.268 (r)-2-hexanol xanthobacter autotrophicus 2.7 2.7 1 PMID:15157110 -1.1.1.268 (r)-2-octanol xanthobacter autotrophicus 1.7 1.7 1 PMID:15157110 -1.1.1.268 (r)-2-pentanol xanthobacter autotrophicus 1.1 1.1 1 PMID:15157110 -1.1.1.268 (s)-2-butanol xanthobacter autotrophicus 9.3 5.75 2 PMID:15157110;PMID:20302306 -1.1.1.268 (s)-2-pentanol xanthobacter autotrophicus 2.9 2.9 1 PMID:15157110 -1.1.1.268 2-(2-hydroxyethylthio)ethanesulfonate xanthobacter autotrophicus 0.55 0.42000000000000004 2 PMID:20302306;PMID:30592559 -1.1.1.268 2-(2-hydroxyethylthio)ethanesulfonate xanthobacter sp. 0.29 0.29 1 PMID:11851420 -1.1.1.268 2-(2-ketopropylthio)ethanesulfonate xanthobacter autotrophicus 24.5 24.5 1 PMID:15157110 -1.1.1.268 2-(r)-hydroxypropyl-com xanthobacter autotrophicus 49.0 39.0 2 PMID:20302306;PMID:20551308 -1.1.1.268 2-(r)-hydroxypropyl-com xanthobacter sp. 25.8 25.8 1 PMID:11851420 -1.1.1.268 2-(s)-hydroxypropyl-com xanthobacter autotrophicus 0.12 0.12 1 PMID:20302306 -1.1.1.268 2-[(r)-2-hydroxypropylthio]ethanesulfonate xanthobacter autotrophicus 26.8 26.8 1 PMID:15157110 -1.1.1.268 2-[(s)-2-hydroxypropylthio]ethanesulfonate xanthobacter autotrophicus 0.044 0.044 1 PMID:15157110 -1.1.1.268 2-butanone xanthobacter autotrophicus 0.027 0.027 1 PMID:15157110 -1.1.1.268 2-oxopropyl-com xanthobacter autotrophicus 29.0 29.0 1 PMID:20302306 -1.1.1.268 2-oxopropyl-com xanthobacter sp. 24.5 24.5 1 PMID:11851420 -1.1.1.268 2-propanol xanthobacter autotrophicus 2.9 2.9 2 PMID:15157110;PMID:30592559 -1.1.1.269 (r)-2-butanol xanthobacter autotrophicus 1.0 1.0 1 PMID:20302306 -1.1.1.269 (s)-2-butanol xanthobacter autotrophicus 2.6 2.6 1 PMID:20302306 -1.1.1.269 2-(2-hydroxyethylthio)ethanesulfonate xanthobacter autotrophicus 3.8 3.8 1 PMID:20302306 -1.1.1.269 2-(r)-hydroxypropyl-com xanthobacter autotrophicus 49.0 27.25 2 PMID:20302306 -1.1.1.269 2-(s)-hydroxypropyl-com xanthobacter autotrophicus 25.0 12.56 2 PMID:20302306 -1.1.1.269 2-butanone xanthobacter autotrophicus 0.044 0.044 1 PMID:20302306 -1.1.1.269 2-oxopropyl-com xanthobacter autotrophicus 29.0 20.0 2 PMID:20302306 -1.1.1.269 2-propanol xanthobacter autotrophicus 2.0 2.0 1 PMID:20302306 -1.1.1.27 (s)-lactate cryptosporidium parvum 4.5e-05 4.5e-05 1 PMID:25542170 -1.1.1.27 (s)-lactate plasmodium falciparum 65.0 65.0 1 PMID:15147206 -1.1.1.27 (s)-lactate plasmodium malariae 38.33 38.33 1 PMID:15147206 -1.1.1.27 (s)-lactate plasmodium ovale 25.0 25.0 1 PMID:15147206 -1.1.1.27 (s)-lactate plasmodium vivax 12.33 12.33 1 PMID:15147206 -1.1.1.27 2-oxobutyrate plasmodium falciparum 80.0 80.0 1 PMID:17459101 -1.1.1.27 2-oxovalerate plasmodium falciparum 0.64 0.64 1 PMID:17459101 -1.1.1.27 3,4-dihydroxyphenylpyruvate limosilactobacillus fermentum 0.293 0.293 1 * -1.1.1.27 3-acetylpyridine adenine dinucleotide anas platyrhynchos 1.4 1.4 1 PMID:1989512 -1.1.1.27 3-acetylpyridine adenine dinucleotide gallus gallus 16.0 16.0 1 PMID:1989512 -1.1.1.27 3-acetylpyridine adenine dinucleotide plasmodium falciparum 250.0 250.0 1 PMID:15147206 -1.1.1.27 3-acetylpyridine adenine dinucleotide plasmodium malariae 233.3 233.3 1 PMID:15147206 -1.1.1.27 3-acetylpyridine adenine dinucleotide plasmodium ovale 153.3 153.3 1 PMID:15147206 -1.1.1.27 3-acetylpyridine adenine dinucleotide plasmodium vivax 333.3 333.3 1 PMID:15147206 -1.1.1.27 4-methyl-2-oxopentanoate plasmodium falciparum 0.33 0.33 1 PMID:9051732 -1.1.1.27 apad+ cryptosporidium parvum 0.000248 0.000248 1 PMID:25542170 -1.1.1.27 apadh cryptosporidium parvum 0.00386 0.00386 1 PMID:25542170 -1.1.1.27 bromopyruvate anas platyrhynchos 269.0 269.0 1 PMID:1989512 -1.1.1.27 epsilon-nad+ anas platyrhynchos 6.2 5.3 3 PMID:1989512 -1.1.1.27 fluoropyruvate gallus gallus 98.0 98.0 1 PMID:1989512 -1.1.1.27 l-lactate plasmodium falciparum 40.0 40.0 1 PMID:17459101 -1.1.1.27 nad+ anas platyrhynchos 6.9 6.9 1 PMID:1989512 -1.1.1.27 nad+ cryptosporidium parvum 5.5e-05 5.5e-05 1 PMID:25542170 -1.1.1.27 nad+ gallus gallus 60.0 31.65 2 PMID:1989512 -1.1.1.27 nad+ geobacillus stearothermophilus 32.0 32.0 1 PMID:16012175 -1.1.1.27 nad+ plasmodium falciparum 65.0 52.5 2 PMID:15147206;PMID:17459101 -1.1.1.27 nad+ plasmodium malariae 38.33 38.33 1 PMID:15147206 -1.1.1.27 nad+ plasmodium ovale 25.0 25.0 1 PMID:15147206 -1.1.1.27 nad+ plasmodium vivax 12.33 12.33 1 PMID:15147206 -1.1.1.27 nadh babesia bovis 216.7 216.7 1 PMID:15478796 -1.1.1.27 nadh cryptosporidium parvum 0.00208 0.00208 1 PMID:25542170 -1.1.1.27 nadh homarus americanus 2330.0 2330.0 1 * -1.1.1.27 nadh limosilactobacillus fermentum 64.42 64.42 1 * -1.1.1.27 nadh plasmodium falciparum 148.3 122.15 2 PMID:15147206;PMID:17459101 -1.1.1.27 nadh plasmodium malariae 125.0 125.0 1 PMID:15147206 -1.1.1.27 nadh plasmodium ovale 266.7 266.7 1 PMID:15147206 -1.1.1.27 nadh plasmodium vivax 126.7 126.7 1 PMID:15147206 -1.1.1.27 nadph limosilactobacillus fermentum 10.37 10.37 1 * -1.1.1.27 nicotinamide hypoxanthine dinucleotide anas platyrhynchos 18.8 5.5 3 PMID:1989512 -1.1.1.27 nicotinamide hypoxanthine dinucleotide gallus gallus 1.1 1.1 1 PMID:1989512 -1.1.1.27 phenylpyruvate lacticaseibacillus casei 6467.0 3280.85 2 PMID:29800600 -1.1.1.27 phenylpyruvate plasmodium falciparum 39.5 39.5 1 PMID:9051732 -1.1.1.27 pyruvate anas platyrhynchos 204.0 204.0 1 PMID:1989512 -1.1.1.27 pyruvate cryptosporidium parvum 0.00209 0.00209 1 PMID:25542170 -1.1.1.27 pyruvate deinococcus radiodurans 884.0 884.0 1 PMID:17936781 -1.1.1.27 pyruvate enterococcus mundtii 1600.0 1500.0 3 PMID:25379380 -1.1.1.27 pyruvate geobacillus stearothermophilus 327.2 250.0 3 PMID:17947381;PMID:18025556 -1.1.1.27 pyruvate lactobacillus helveticus 643.0 643.0 1 PMID:9212432 -1.1.1.27 pyruvate limosilactobacillus fermentum 12.45 12.45 1 * -1.1.1.27 pyruvate oryctolagus cuniculus 276.5 223.6 2 * -1.1.1.27 pyruvate plasmodium berghei 106.0 106.0 1 PMID:12967707 -1.1.1.27 pyruvate plasmodium falciparum 180.0 122.15 4 PMID:12967707;PMID:15147206;PMID:17459101;PMID:9051732 -1.1.1.27 pyruvate plasmodium malariae 125.0 125.0 1 PMID:15147206 -1.1.1.27 pyruvate plasmodium ovale 266.7 266.7 1 PMID:15147206 -1.1.1.27 pyruvate plasmodium vivax 126.7 126.7 1 PMID:15147206 -1.1.1.27 pyruvate rhizopus delemar 350.0 226.0 4 * -1.1.1.27 pyruvate rhizopus oryzae atcc 9363 320.0 281.0 4 * -1.1.1.27 pyruvate sporolactobacillus inulinus 5.9 4.1 2 PMID:30066438 -1.1.1.27 pyruvate thermus thermophilus 676.0 676.0 1 PMID:17936781 -1.1.1.27 pyruvate ethyl ester anas platyrhynchos 176.0 176.0 1 PMID:1989512 -1.1.1.27 pyruvate methyl ester anas platyrhynchos 227.0 227.0 1 PMID:1989512 -1.1.1.270 17beta-hydroxy-5alpha-androstan-3-one homo sapiens 0.052 0.0493 3 PMID:14672942 -1.1.1.270 3-oxodeoxycholic acid eggerthella sp. cag:298 0.007 0.007 1 PMID:29330189 -1.1.1.270 5beta-dihydrotestosterone oryctolagus cuniculus 0.113 0.113 1 PMID:22874434 -1.1.1.270 5beta-pregnane-21-ol-3,20-dione oryctolagus cuniculus 0.092 0.092 1 PMID:22874434 -1.1.1.270 dehydroepiandrosterone homo sapiens 0.055 0.055 1 PMID:29031687 -1.1.1.270 isodeoxycholic acid eggerthella sp. cag:298 0.022 0.022 1 PMID:29330189 -1.1.1.270 methylglyoxal oryctolagus cuniculus 0.3 0.3 1 PMID:22874434 -1.1.1.270 nad+ homo sapiens 0.058 0.058 1 PMID:29031687 -1.1.1.270 nadph oryctolagus cuniculus 0.73 0.73 1 PMID:22874434 -1.1.1.270 pyridine-3-aldehyde oryctolagus cuniculus 0.72 0.72 1 PMID:22874434 -1.1.1.271 gdp-4-keto-6-deoxy-d-mannose helicobacter pylori 0.75 0.75 1 PMID:11444851 -1.1.1.271 gdp-6-deoxy-4-keto-mannose escherichia coli k-12 1.0 1.0 2 PMID:19053199 -1.1.1.274 2,5-didehydro-d-gluconate corynebacterium sp. 8.33 8.33 1 PMID:3597405 -1.1.1.274 ethyl 2-methylacetoacetate escherichia coli 2.6 2.6 1 PMID:11934293 -1.1.1.274 ethyl-2-methylacetoacetate escherichia coli 2.6 2.6 1 PMID:11934293 -1.1.1.274 methylglyoxal escherichia coli 81.0 29.15 3 PMID:16077126 -1.1.1.274 nadh corynebacterium sp. 2.83 2.83 1 PMID:12009883 -1.1.1.276 l-allo-threonine escherichia coli 5.76 5.76 1 PMID:12535615 -1.1.1.276 l-allo-threonine saccharomyces cerevisiae 43.8 43.8 1 PMID:12535615 -1.1.1.276 l-serine escherichia coli 4.2 4.2 1 PMID:12535615 -1.1.1.276 l-serine saccharomyces cerevisiae 11.0 11.0 1 PMID:12535615 -1.1.1.28 (r)-lactate heyndrickxia coagulans 0.07 0.07 1 PMID:25217009 -1.1.1.28 (r)-lactate leuconostoc mesenteroides subsp. mesenteroides 2280.0 1595.0 2 PMID:22975125;PMID:30008205 -1.1.1.28 2-ketobutyrate lactiplantibacillus pentosus 118.0 118.0 1 PMID:16428303 -1.1.1.28 2-ketocaproate lactiplantibacillus pentosus 21.0 21.0 1 PMID:16428303 -1.1.1.28 2-ketoglutarate lactiplantibacillus pentosus 0.51 0.51 1 PMID:16428303 -1.1.1.28 2-ketoisocaproate lactiplantibacillus pentosus 11.1 11.1 1 PMID:16428303 -1.1.1.28 2-ketoisovalerate lactiplantibacillus pentosus 27.0 27.0 1 PMID:16428303 -1.1.1.28 2-ketovalerate lactiplantibacillus pentosus 5.7 5.7 1 PMID:16428303 -1.1.1.28 2-oxobutanoate leuconostoc mesenteroides subsp. mesenteroides 2220.0 2220.0 1 PMID:30008205 -1.1.1.28 2-oxobutanoate pediococcus acidilactici 50.7 50.7 1 PMID:31190286 -1.1.1.28 2-oxobutyrate escherichia coli 31.0 31.0 1 PMID:25401076 -1.1.1.28 2-oxobutyrate fusobacterium nucleatum subsp. nucleatum 140.0 140.0 1 PMID:25401076 -1.1.1.28 2-oxobutyrate lactiplantibacillus pentosus 120.0 120.0 1 PMID:15734738 -1.1.1.28 2-oxobutyrate pseudomonas aeruginosa 100.0 100.0 1 PMID:25401076 -1.1.1.28 2-oxocaproate fusobacterium nucleatum subsp. nucleatum 230.0 230.0 1 PMID:25401076 -1.1.1.28 2-oxocaproate pseudomonas aeruginosa 160.0 160.0 1 PMID:25401076 -1.1.1.28 2-oxoisocaproate fusobacterium nucleatum subsp. nucleatum 200.0 200.0 1 PMID:25401076 -1.1.1.28 2-oxoisocaproate pseudomonas aeruginosa 39.0 39.0 1 PMID:25401076 -1.1.1.28 2-oxoisovalerate fusobacterium nucleatum subsp. nucleatum 120.0 120.0 1 PMID:25401076 -1.1.1.28 2-oxovalerate fusobacterium nucleatum subsp. nucleatum 140.0 140.0 1 PMID:25401076 -1.1.1.28 2-oxovalerate pseudomonas aeruginosa 69.0 69.0 1 PMID:25401076 -1.1.1.28 3,4-dihydroxyphenylpyruvic acid limosilactobacillus reuteri 2.17 1.15 2 PMID:30129993 -1.1.1.28 3-methyl-2-oxobutanoate pediococcus acidilactici 33.9 33.9 1 PMID:31190286 -1.1.1.28 glyoxylate escherichia coli 100.0 100.0 1 PMID:25401076 -1.1.1.28 glyoxylate fusobacterium nucleatum subsp. nucleatum 11.0 11.0 1 PMID:25401076 -1.1.1.28 glyoxylate lactiplantibacillus pentosus 270.0 270.0 1 PMID:15734738 -1.1.1.28 glyoxylate pseudomonas aeruginosa 880.0 880.0 1 PMID:25401076 -1.1.1.28 hydroxypyruvate escherichia coli 50.0 50.0 1 PMID:25401076 -1.1.1.28 hydroxypyruvate fusobacterium nucleatum subsp. nucleatum 160.0 160.0 1 PMID:25401076 -1.1.1.28 hydroxypyruvate lactiplantibacillus pentosus 260.0 258.5 2 PMID:15734738;PMID:16428303 -1.1.1.28 hydroxypyruvate pseudomonas aeruginosa 420.0 420.0 1 PMID:25401076 -1.1.1.28 nad+ lactobacillus helveticus 2.84 2.84 1 PMID:32175634 -1.1.1.28 nad+ lactobacillus jensenii 4.42 3.65 3 * -1.1.1.28 nad+ leuconostoc mesenteroides subsp. mesenteroides 340.0 340.0 1 PMID:30008205 -1.1.1.28 nadh escherichia coli 730.0 700.0 4 PMID:25401076 -1.1.1.28 nadh fusobacterium nucleatum subsp. nucleatum 110.0 94.0 4 PMID:25401076 -1.1.1.28 nadh lactobacillus jensenii 516.4 144.4 3 * -1.1.1.28 nadh leuconostoc mesenteroides subsp. mesenteroides 3260.0 3260.0 1 PMID:30008205 -1.1.1.28 nadh limosilactobacillus fermentum 67.4 67.4 1 PMID:28881036 -1.1.1.28 nadh limulus polyphemus 633.0 633.0 1 PMID:1128269 -1.1.1.28 nadh pseudomonas aeruginosa 310.0 290.0 2 PMID:25401076 -1.1.1.28 nicotinamide cytosine dinucleotide lactobacillus helveticus 0.66 0.66 1 PMID:32175634 -1.1.1.28 oxaloacetate escherichia coli 1100.0 1100.0 1 PMID:25401076 -1.1.1.28 oxaloacetate fusobacterium nucleatum subsp. nucleatum 80.0 80.0 1 PMID:25401076 -1.1.1.28 oxaloacetate lactiplantibacillus pentosus 280.0 280.0 1 PMID:16428303 -1.1.1.28 oxaloacetate leuconostoc mesenteroides subsp. mesenteroides 1570.0 1570.0 1 PMID:30008205 -1.1.1.28 oxaloacetate pseudomonas aeruginosa 410.0 410.0 1 PMID:25401076 -1.1.1.28 phenylpyruvate furfurilactobacillus rossiae 12.29 12.29 1 PMID:32099742 -1.1.1.28 phenylpyruvate fusobacterium nucleatum subsp. nucleatum 120.0 120.0 1 PMID:25401076 -1.1.1.28 phenylpyruvate lactiplantibacillus pentosus 40.0 40.0 1 PMID:16428303 -1.1.1.28 phenylpyruvate lactobacillus delbrueckii subsp. bulgaricus 11.3 11.3 1 PMID:24292439 -1.1.1.28 phenylpyruvate limosilactobacillus fermentum 122.7 122.7 1 PMID:28881036 -1.1.1.28 phenylpyruvate pediococcus acidilactici 305.0 173.15 2 PMID:22261863;PMID:31190286 -1.1.1.28 phenylpyruvate pediococcus pentosaceus 173.0 173.0 1 PMID:22484960 -1.1.1.28 phenylpyruvate pseudomonas aeruginosa 18.0 18.0 1 PMID:25401076 -1.1.1.28 pyruvate escherichia coli 410.0 390.0 4 PMID:25401076 -1.1.1.28 pyruvate fusobacterium nucleatum subsp. nucleatum 100.0 83.5 4 PMID:25401076 -1.1.1.28 pyruvate heyndrickxia coagulans 11.3 11.3 1 PMID:25217009 -1.1.1.28 pyruvate lactiplantibacillus pentosus 321.0 320.5 2 PMID:15734738;PMID:16428303 -1.1.1.28 pyruvate lactiplantibacillus plantarum subsp. plantarum 91.3 91.3 1 PMID:25217009 -1.1.1.28 pyruvate lactobacillus delbrueckii subsp. bulgaricus 235.5 235.5 1 PMID:25217009 -1.1.1.28 pyruvate leuconostoc mesenteroides subsp. mesenteroides 29000.0 15875.0 2 PMID:22975125;PMID:30008205 -1.1.1.28 pyruvate pediococcus pentosaceus 320.0 320.0 1 PMID:22484960 -1.1.1.28 pyruvate pseudomonas aeruginosa 400.0 265.0 4 PMID:25401076 -1.1.1.28 pyruvate sporolactobacillus inulinus 512.2 60.25 4 PMID:26398356;PMID:30066438 -1.1.1.28 pyruvate sporolactobacillus laevolacticus 0.00046 0.00046 1 * -1.1.1.282 3-dehydroquinate corynebacterium glutamicum 114.0 61.655 2 PMID:23306642 -1.1.1.282 3-dehydroshikimate corynebacterium glutamicum 329.0 167.335 2 PMID:23306642;PMID:25524738 -1.1.1.282 l-quinate corynebacterium glutamicum 104.9 32.71 4 PMID:23306642;PMID:23929881;PMID:25524738 -1.1.1.282 l-quinate escherichia coli 0.113 0.0815 2 PMID:12637497;PMID:15596430 -1.1.1.282 l-quinate pseudomonas putida 0.0063 0.0063 1 PMID:23142411 -1.1.1.282 nad+ corynebacterium glutamicum 223.1 83.46 4 PMID:23929881 -1.1.1.282 nad+ escherichia coli 0.142 0.105 3 PMID:12637497;PMID:15596430 -1.1.1.282 nad+ nicotiana tabacum 20.8 12.3 2 PMID:29890023 -1.1.1.282 nad+ pseudomonas putida 2.8 1.40275 2 PMID:23142411 -1.1.1.282 nad+ pseudomonas putida kt2440 61.1 58.400000000000006 2 PMID:18669580 -1.1.1.282 nad+ solanum lycopersicum 10.5 5.62 2 PMID:29890023 -1.1.1.282 nadp+ brassica napus 8.6 7.8 2 PMID:29890023 -1.1.1.282 nadp+ brassica rapa 0.335 0.16840000000000002 2 PMID:29890023 -1.1.1.282 nadp+ escherichia coli 0.117 0.0835 2 PMID:12637497 -1.1.1.282 nadp+ pseudomonas putida 0.022 0.022 1 PMID:23142411 -1.1.1.282 quinate brassica napus 8.5 8.5 1 PMID:29890023 -1.1.1.282 quinate brassica rapa 0.493 0.493 1 PMID:29890023 -1.1.1.282 quinate nicotiana tabacum 16.2 16.2 1 PMID:29890023 -1.1.1.282 quinate pseudomonas putida kt2440 37.7 37.7 1 PMID:18669580 -1.1.1.282 quinate solanum lycopersicum 9.4 9.4 1 PMID:29890023 -1.1.1.282 shikimate corynebacterium glutamicum 214.1 30.13 5 PMID:23306642;PMID:23929881;PMID:25524738 -1.1.1.282 shikimate escherichia coli 0.117 0.091 3 PMID:12637497;PMID:15596430 -1.1.1.282 shikimate pseudomonas putida 3.9 1.9635 2 PMID:23142411 -1.1.1.282 shikimate pseudomonas putida kt2440 55.7 55.7 1 PMID:18669580 -1.1.1.283 2-nitrobenzaldehyde synechococcus sp. 1.31 1.31 1 PMID:16804176 -1.1.1.283 3-nitrobenzaldehyde synechococcus sp. 1.12 1.12 1 PMID:16804176 -1.1.1.283 4-nitrobenzaldehyde synechococcus sp. 1.24 1.24 1 PMID:16804176 -1.1.1.283 benzaldehyde synechococcus sp. 1.05 1.05 1 PMID:16804176 -1.1.1.283 d-galactose synechococcus sp. 0.68 0.68 1 PMID:16804176 -1.1.1.283 d-glucose synechococcus sp. 0.62 0.62 1 PMID:16804176 -1.1.1.283 d-xylose synechococcus sp. 1.22 1.22 1 PMID:16804176 -1.1.1.283 dl-glyceraldehyde synechococcus sp. 0.52 0.52 1 PMID:16804176 -1.1.1.283 isopentaldehyde synechococcus sp. 0.65 0.65 1 PMID:16804176 -1.1.1.283 l-arabinose synechococcus sp. 1.27 1.27 1 PMID:16804176 -1.1.1.283 methyl glyoxal kluyveromyces marxianus 4.0 3.25 2 PMID:26223585 -1.1.1.283 methylglyoxal methanocaldococcus jannaschii 0.0022 0.0022 1 PMID:28644554 -1.1.1.283 methylglyoxal synechococcus sp. 0.85 0.85 1 PMID:16804176 -1.1.1.283 nadph kluyveromyces marxianus 3.67 3.17 2 PMID:26223585 -1.1.1.283 nadph methanocaldococcus jannaschii 0.12 0.12 1 PMID:28644554 -1.1.1.284 12-hydroxydodecanoic acid arabidopsis thaliana 5.6 5.6 1 PMID:12913179 -1.1.1.284 12-hydroxydodecanoic acid homo sapiens 0.217 0.217 1 PMID:10978156 -1.1.1.284 3-nitrotyrosine helicobacter pylori 0.1 0.1 1 PMID:25132107 -1.1.1.284 cinnamyl alcohol arabidopsis thaliana 20.33 12.864999999999998 2 PMID:12913179 -1.1.1.284 farnesol arabidopsis thaliana 2.1 1.1 2 PMID:12913179 -1.1.1.284 formaldehyde komagataella pastoris 0.267 0.267 1 * -1.1.1.284 geraniol arabidopsis thaliana 20.0 20.0 1 PMID:12913179 -1.1.1.284 glutathione komagataella pastoris 0.233 0.233 1 * -1.1.1.284 metronidazole helicobacter pylori 0.6 0.6 1 PMID:25132107 -1.1.1.284 nad+ homo sapiens 2.5 1.04 3 PMID:10978156;PMID:16605250 -1.1.1.284 nadh chlamydomonas reinhardtii 27.0 27.0 1 PMID:33316743 -1.1.1.284 nadh homo sapiens 34.5 34.5 1 PMID:16605250 -1.1.1.284 nitrofurantoin helicobacter pylori 0.5 0.5 1 PMID:25132107 -1.1.1.284 nitrofurazone helicobacter pylori 1.0 1.0 1 PMID:25132107 -1.1.1.284 s-(hydroxymethyl)glutathione arabidopsis thaliana 22.5 22.5 1 PMID:12913179 -1.1.1.284 s-hydroxymethyl glutathione bos taurus 1.42 1.13 3 PMID:2793862 -1.1.1.284 s-hydroxymethyl glutathione drosophila melanogaster 16.0 16.0 1 PMID:9059642 -1.1.1.284 s-hydroxymethyl glutathione escherichia coli 156.0 156.0 1 PMID:9059642 -1.1.1.284 s-hydroxymethyl glutathione homo sapiens 3.33 2.185 2 PMID:10978156;PMID:9059642 -1.1.1.284 s-hydroxymethyl glutathione lathyrus oleraceus 6.33 6.33 1 PMID:9059642 -1.1.1.284 s-hydroxymethyl glutathione rattus norvegicus 3.6 3.6 1 PMID:9059642 -1.1.1.284 s-hydroxymethyl glutathione saccharomyces cerevisiae 88.3 88.3 1 PMID:9059642 -1.1.1.284 s-hydroxymethylglutathione branchiostoma floridae 2.5 2.5 1 PMID:16763671 -1.1.1.284 s-hydroxymethylglutathione homo sapiens 2.5 2.5 2 PMID:16605250;PMID:18412547 -1.1.1.284 s-hydroxymethylglutathione saccharomyces cerevisiae 51.7 51.7 1 PMID:10608852 -1.1.1.284 s-nitrosocysteine helicobacter pylori 0.6 0.6 1 PMID:25132107 -1.1.1.284 s-nitrosoglutathione branchiostoma floridae 16.7 16.7 1 PMID:16763671 -1.1.1.284 s-nitrosoglutathione chlamydomonas reinhardtii 26.6 26.6 1 PMID:33316743 -1.1.1.284 s-nitrosoglutathione helicobacter pylori 0.5 0.5 1 PMID:25132107 -1.1.1.284 s-nitrosoglutathione homo sapiens 72000.0 24.65 4 PMID:16605250;PMID:18412547;PMID:18826943;PMID:19011746 -1.1.1.284 s-nitrosoglutathione staphylococcus aureus 0.02 0.02 1 PMID:19286809 -1.1.1.286 3-isopropylmalate deinococcus radiodurans 0.371 0.371 1 PMID:16139794 -1.1.1.286 3-isopropylmalate thermococcus kodakarensis 4.8 4.8 1 PMID:27831491 -1.1.1.286 homoisocitrate deinococcus radiodurans 46.2 46.2 1 PMID:16139794 -1.1.1.286 homoisocitrate pyrococcus horikoshii 13.7 13.7 1 PMID:15845397 -1.1.1.286 homoisocitrate sulfolobus acidocaldarius 37.0 37.0 1 PMID:27590116 -1.1.1.286 homoisocitrate thermococcus kodakarensis 17.0 17.0 1 PMID:27831491 -1.1.1.286 homoisocitrate thermus thermophilus 171.0 102.0 2 PMID:12427751;PMID:27601325 -1.1.1.286 isocitrate deinococcus radiodurans 42.8 42.8 1 PMID:16139794 -1.1.1.286 isocitrate pyrococcus horikoshii 14.8 14.8 1 PMID:15845397 -1.1.1.286 isocitrate sulfolobus acidocaldarius 61.0 61.0 1 PMID:27590116 -1.1.1.286 isocitrate thermococcus kodakarensis 5.0 5.0 1 PMID:27831491 -1.1.1.286 isocitrate thermus thermophilus 171.0 123.5 2 PMID:12427751;PMID:27601325 -1.1.1.286 nad+ deinococcus radiodurans 30.3 30.3 1 PMID:16139794 -1.1.1.286 nad+ pyrococcus horikoshii 21.8 21.8 1 PMID:15845397 -1.1.1.287 d-arabitol gluconobacter oxydans 876.0 567.0 2 PMID:16165327;PMID:19629658 -1.1.1.287 d-fructose gluconobacter oxydans 224.0 224.0 1 PMID:16165327 -1.1.1.287 d-mannitol gluconobacter oxydans 243.0 139.15 2 PMID:16165327;PMID:19629658 -1.1.1.287 d-ribitol gluconobacter oxydans 13.4 13.4 1 PMID:19629658 -1.1.1.287 d-sorbitol gluconobacter oxydans 19.7 11.135 2 PMID:16165327;PMID:19629658 -1.1.1.287 d-xylulose gluconobacter oxydans 196.0 196.0 1 PMID:16165327 -1.1.1.287 glycerol gluconobacter oxydans 16.3 8.815000000000001 2 PMID:16165327;PMID:19629658 -1.1.1.287 meso-erythritol gluconobacter oxydans 1.28 1.28 1 PMID:16165327 -1.1.1.287 xylitol gluconobacter oxydans 177.2 177.2 1 PMID:19629658 -1.1.1.289 d-fructose candida albicans 154.0 154.0 1 PMID:16134116 -1.1.1.289 l-sorbose candida albicans 782.0 782.0 1 PMID:16134116 -1.1.1.29 hydroxypyruvate arabidopsis thaliana 284.0 222.0 2 PMID:32156771 -1.1.1.29 nadh arabidopsis thaliana 248.0 248.0 1 PMID:32156771 -1.1.1.29 nadph arabidopsis thaliana 162.0 162.0 1 PMID:32156771 -1.1.1.290 2-oxoglutarate escherichia coli 1.0 1.0 1 PMID:20831184 -1.1.1.290 4-phospho-d-erythronate escherichia coli 1.4 1.4 2 PMID:20831184 -1.1.1.290 oxaloacetic acid escherichia coli 1.1 1.1 1 PMID:20831184 -1.1.1.290 pyruvate escherichia coli 1.3 1.3 1 PMID:20831184 -1.1.1.292 1,5-anhydro-d-fructose ensifer adhaerens 1300.0 251.35 4 PMID:16461673;PMID:16906761 -1.1.1.292 1,5-anhydro-d-fructose mus musculus 9.3 9.3 1 PMID:18323634 -1.1.1.292 d-glucosone ensifer adhaerens 63.2 63.2 1 PMID:16461673 -1.1.1.295 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide oryza sativa 0.4 0.24000000000000002 2 PMID:27337377 -1.1.1.295 oryzalexin a oryza sativa 0.023 0.0215 2 PMID:27337377 -1.1.1.298 3-hydroxypropanoate bacillus cereus 0.21 0.21 1 PMID:19517068 -1.1.1.298 3-hydroxypropionate bacillus cereus 0.21 0.21 2 PMID:19517068 -1.1.1.298 malonate semialdehyde metallosphaera sedula 115.0 115.0 1 PMID:19684143 -1.1.1.298 nadph metallosphaera sedula 115.0 115.0 1 PMID:19684143 -1.1.1.299 l-malate flavobacterium frigidimaris 138.0 65.8 4 PMID:16306697 -1.1.1.299 nad+ flavobacterium frigidimaris 139.0 66.0 4 PMID:16306697 -1.1.1.299 oxaloacetate ignicoccus islandicus 444.0 444.0 1 PMID:31301348 -1.1.1.299 pyruvate ignicoccus islandicus 8.0 8.0 1 PMID:31301348 -1.1.1.3 l-aspartate 4-semialdehyde glycine max 22.58 12.280000000000001 6 PMID:19897476 -1.1.1.3 l-homoserine bacillus subtilis 1.07 1.07 1 PMID:33046675 -1.1.1.3 l-homoserine escherichia coli 24.0 1.9049999999999998 4 PMID:11888289 -1.1.1.3 l-homoserine glycine max 10.15 0.75 6 PMID:19897476 -1.1.1.3 nad+ pyrococcus horikoshii 70.1 70.1 1 PMID:26154028 -1.1.1.3 nad+ thermus thermophilus 6.66 6.66 1 PMID:30423116 -1.1.1.3 nadp+ bacillus subtilis 1.1 1.1 1 PMID:33046675 -1.1.1.3 nadp+ thermus thermophilus 2.12 2.12 1 PMID:30423116 -1.1.1.30 (r)-3-hydroxybutanoate pseudomonas putida 1382.0 907.0 2 PMID:16888731;PMID:17958702 -1.1.1.30 (r)-3-hydroxybutanoate ralstonia pickettii 310.0 245.0 2 PMID:16935252 -1.1.1.30 acetoacetate alcaligenes faecalis 97.16 51.03 2 * -1.1.1.30 acetoacetate pseudomonas fragi 120.0 120.0 1 PMID:19122202 -1.1.1.30 acetoacetate ralstonia pickettii 150.0 110.0 3 PMID:16935252;PMID:19219638 -1.1.1.30 d-3-hydroxybutyrate pseudomonas fragi 370.0 340.0 2 PMID:19122202 -1.1.1.30 d-3-hydroxybutyrate ralstonia pickettii 500.0 310.0 3 PMID:19219638 -1.1.1.30 levulinic acid alcaligenes faecalis 0.00768 0.006840000000000001 2 * -1.1.1.30 nad+ ralstonia pickettii 360.0 340.0 3 PMID:16935252;PMID:19219638 -1.1.1.30 nadh ralstonia pickettii 740.0 280.0 3 PMID:16935252;PMID:19219638 -1.1.1.300 all-trans-retinal homo sapiens 0.3 0.18 3 PMID:14674758;PMID:16787387;PMID:18396173 -1.1.1.300 all-trans-retinol homo sapiens 0.2 0.1003 2 PMID:14674758;PMID:16787387 -1.1.1.300 nad+ bacillus cereus 0.0017 0.0017 1 PMID:27107124 -1.1.1.300 nadp+ bacillus cereus 0.0018 0.0018 1 PMID:27107124 -1.1.1.300 nadph bacillus cereus 0.00055 0.00055 1 PMID:27107124 -1.1.1.300 retinal bacillus cereus 0.0047 0.00335 2 PMID:27107124 -1.1.1.304 (2s,3s)-2,3-butanediol bacillus licheniformis 591.0 591.0 1 PMID:26494135 -1.1.1.304 (3s)-acetoin bacillus licheniformis 202.0 202.0 1 PMID:26494135 -1.1.1.304 diacetyl bacillus licheniformis 1222.0 1222.0 1 PMID:26494135 -1.1.1.304 diacetyl mycobacterium sp. 163.0 163.0 1 PMID:25082080 -1.1.1.304 nad+ bacillus licheniformis 748.0 748.0 1 PMID:26494135 -1.1.1.304 nadh bacillus licheniformis 1274.0 1274.0 1 PMID:26494135 -1.1.1.304 nadh mycobacterium sp. 110.0 110.0 1 PMID:25082080 -1.1.1.305 nad+ ralstonia solanacearum 0.32 0.32 1 PMID:20118241 -1.1.1.305 udp-glucuronic acid ralstonia solanacearum 0.285 0.285 1 PMID:20118241 -1.1.1.307 5,6-dideoxy-5,6-difluoro-d-glucofuranose sungouiella intermedia 12.0 12.0 1 PMID:10548539 -1.1.1.307 5,6-dideoxy-5,6-difluoro-d-glucofuranose yamadazyma tenuis 18.0 18.0 1 PMID:10548539 -1.1.1.307 5,6-dideoxy-5-fluoro-d-glucofuranose sungouiella intermedia 13.0 13.0 1 PMID:10548539 -1.1.1.307 5,6-dideoxy-5-fluoro-d-glucofuranose yamadazyma tenuis 18.0 18.0 1 PMID:10548539 -1.1.1.307 5,6-dideoxy-6-fluoro-d-xylo-hexofuranose yamadazyma tenuis 18.0 18.0 1 PMID:10548539 -1.1.1.307 5,6-dideoxy-6-fluoro-d-xylohexofuranose sungouiella intermedia 21.0 21.0 1 PMID:10548539 -1.1.1.307 5,6-dideoxy-d-xylo-hexofuranose yamadazyma tenuis 18.0 18.0 1 PMID:10548539 -1.1.1.307 5,6-dideoxy-d-xylohexofuranose sungouiella intermedia 14.0 14.0 1 PMID:10548539 -1.1.1.307 5-deoxy-d-xylofuranose sungouiella intermedia 13.5 13.5 1 PMID:10548539 -1.1.1.307 5-deoxy-d-xylofuranose yamadazyma tenuis 18.0 18.0 1 PMID:10548539 -1.1.1.307 5-fluoro-5-deoxy-d-xylofuranose sungouiella intermedia 15.5 15.5 1 PMID:10548539 -1.1.1.307 5-fluoro-5-deoxy-d-xylofuranose yamadazyma tenuis 19.0 19.0 1 PMID:10548539 -1.1.1.307 6-azido-5,6-dideoxy-5-fluoro-d-glucofuranose sungouiella intermedia 14.0 14.0 1 PMID:10548539 -1.1.1.307 6-azido-5,6-dideoxy-5-fluoro-d-glucofuranose yamadazyma tenuis 16.0 16.0 1 PMID:10548539 -1.1.1.307 cyclohexanecarboxaldehyde yamadazyma tenuis 20.0 20.0 1 PMID:10548539 -1.1.1.307 d-galactose neurospora crassa 1800.0 1800.0 1 PMID:15746370 -1.1.1.307 d-galactose sungouiella intermedia 5.9 5.9 1 PMID:10548539 -1.1.1.307 d-galactose thermochaetoides thermophila 6.5 6.5 1 PMID:30621365 -1.1.1.307 d-galactose yamadazyma tenuis 12.0 12.0 1 PMID:10548539 -1.1.1.307 d-glucose neurospora crassa 1320.0 1320.0 1 PMID:15746370 -1.1.1.307 d-glucose thermochaetoides thermophila 2.7 2.7 1 PMID:30621365 -1.1.1.307 d-ribose neurospora crassa 3120.0 3120.0 1 PMID:15746370 -1.1.1.307 d-xylose candida tropicalis 240.0 240.0 1 PMID:19557353 -1.1.1.307 d-xylose neurospora crassa 3600.0 1955.0 2 PMID:15746370 -1.1.1.307 d-xylose rasamsonia emersonii 324000.0 169875.0 2 PMID:20093741 -1.1.1.307 d-xylose saccharomyces cerevisiae 13.0 12.0 2 PMID:21903144 -1.1.1.307 d-xylose scheffersomyces stipitis 27.5 21.45 2 PMID:18028553 -1.1.1.307 d-xylose sungouiella intermedia 10.5 10.5 3 PMID:10548539;PMID:10681056 -1.1.1.307 d-xylose thermochaetoides thermophila 35.2 22.200000000000003 2 PMID:30621365 -1.1.1.307 d-xylose yamadazyma tenuis 21.5 18.155 4 PMID:10548539;PMID:10661866;PMID:9307017 -1.1.1.307 l-arabinose neurospora crassa 1800.0 1800.0 1 PMID:15746370 -1.1.1.307 l-arabinose thermochaetoides thermophila 8.8 8.8 1 PMID:30621365 -1.1.1.307 nad+ yamadazyma tenuis 0.89 0.89 1 PMID:9307017 -1.1.1.307 nadh neurospora crassa 310.0 310.0 1 PMID:15746370 -1.1.1.307 nadh rasamsonia emersonii 15750.0 15750.0 1 PMID:20093741 -1.1.1.307 nadh scheffersomyces stipitis 15.4 14.25 2 PMID:18028553;PMID:19330484 -1.1.1.307 nadh sungouiella intermedia 16.0 13.6 2 PMID:10681056;PMID:14690376 -1.1.1.307 nadh thermochaetoides thermophila 3.2 3.2 1 PMID:30621365 -1.1.1.307 nadh yamadazyma tenuis 18.1 14.55 2 PMID:15320875;PMID:9307017 -1.1.1.307 nadp+ yamadazyma tenuis 0.82 0.82 1 PMID:9307017 -1.1.1.307 nadph neurospora crassa 3600.0 3600.0 1 PMID:15746370 -1.1.1.307 nadph rasamsonia emersonii 324000.0 324000.0 1 PMID:20093741 -1.1.1.307 nadph scheffersomyces stipitis 40.27 33.885000000000005 2 PMID:18028553;PMID:19330484 -1.1.1.307 nadph sungouiella intermedia 16.3 13.65 2 PMID:10681056;PMID:14690376 -1.1.1.307 nadph thermochaetoides thermophila 11.4 11.4 1 PMID:30621365 -1.1.1.307 nadph yamadazyma tenuis 21.9 17.45 2 PMID:15320875;PMID:9307017 -1.1.1.307 oenanthaldehyde sungouiella intermedia 4.6 4.6 1 PMID:10548539 -1.1.1.307 oenanthaldehyde yamadazyma tenuis 21.0 21.0 1 PMID:10548539 -1.1.1.307 xylitol yamadazyma tenuis 0.87 0.87 1 PMID:9307017 -1.1.1.309 phosphonoacetaldehyde streptomyces viridochromogenes 0.41 0.41 1 PMID:18544530 -1.1.1.31 (r)-3-hydroxyisobutyrate mycobacterium tuberculosis 0.205 0.205 1 PMID:29959185 -1.1.1.31 (r)-3-hydroxyisobutyrate oryctolagus cuniculus 0.49 0.49 1 PMID:3335502 -1.1.1.31 (s)-3-hydroxyisobutyrate arabidopsis thaliana 3.43 3.43 1 PMID:28705827 -1.1.1.31 (s)-3-hydroxyisobutyrate bacillus cereus 24.1 24.1 1 PMID:27120461 -1.1.1.31 (s)-3-hydroxyisobutyrate mycobacterium tuberculosis 1.018 1.018 1 PMID:29959185 -1.1.1.31 (s)-3-hydroxyisobutyrate oryctolagus cuniculus 7.1 7.1 1 PMID:3335502 -1.1.1.31 (s)-3-hydroxyisobutyrate pseudomonas denitrificans (nom. rej.) 80.79 75.80000000000001 2 PMID:23658760 -1.1.1.31 3-hydroxy-2-methylpropanoate arabidopsis thaliana 3.43 3.43 1 PMID:28705827 -1.1.1.31 3-hydroxypropanoic acid mycobacterium tuberculosis 2.53 2.53 1 PMID:29959185 -1.1.1.31 3-hydroxypropionate bacillus cereus 0.21 0.21 1 PMID:19517068 -1.1.1.31 3-hydroxypropionic acid pseudomonas denitrificans (nom. rej.) 32.17 21.485 2 PMID:23658760 -1.1.1.31 l-serine mycobacterium tuberculosis 0.262 0.262 1 PMID:29959185 -1.1.1.31 l-serine pseudomonas denitrificans (nom. rej.) 47.55 47.355 2 PMID:23658760 -1.1.1.31 methyl (2s)-3-hydroxy-2-methylpropanoate pseudomonas denitrificans (nom. rej.) 41.35 38.555 2 PMID:23658760 -1.1.1.31 methyl dl-serine pseudomonas denitrificans (nom. rej.) 7.94 7.28 2 PMID:23658760 -1.1.1.31 nad+ arabidopsis thaliana 2.652 2.652 2 PMID:28705827 -1.1.1.31 nad+ bacillus cereus 15.1 15.1 1 PMID:27120461 -1.1.1.31 nad+ mycobacterium tuberculosis 1.182 1.182 1 PMID:29959185 -1.1.1.31 nad+ pseudomonas denitrificans (nom. rej.) 6.717 6.717 1 PMID:23658760 -1.1.1.31 nadp+ mycobacterium tuberculosis 0.29 0.29 1 PMID:29959185 -1.1.1.311 (s)-1-phenylethanol azoarcus sp. 2.0 2.0 1 PMID:11479712 -1.1.1.311 acetophenone azoarcus sp. 1.6 1.6 1 PMID:11479712 -1.1.1.311 nad+ azoarcus sp. 2.0 2.0 1 PMID:11479712 -1.1.1.311 nadh azoarcus sp. 1.6 1.6 1 PMID:11479712 -1.1.1.313 isethionate klebsiella oxytoca 0.15 0.15 1 PMID:30718306 -1.1.1.313 nadp+ klebsiella oxytoca 0.15 0.15 1 PMID:30718306 -1.1.1.317 4-nitrobenzaldehyde rauvolfia serpentina 8.26 8.26 1 PMID:18409028 -1.1.1.317 perakine rauvolfia serpentina 0.014 0.014 1 PMID:18409028 -1.1.1.318 4-coumaryl acetate larrea tridentata 6.8 6.8 1 PMID:17624297 -1.1.1.318 4-coumaryl acetate ocimum gratissimum 0.003 0.003 1 PMID:27519164 -1.1.1.318 4-coumaryl acetate ocimum kilimandscharicum 0.011 0.011 1 PMID:27519164 -1.1.1.318 4-coumaryl acetate ocimum tenuiflorum 0.013 0.013 1 PMID:27519164 -1.1.1.318 coniferyl acetate clarkia breweri 0.26 0.255 2 PMID:18208524 -1.1.1.318 coniferyl acetate larrea tridentata 6.46 6.46 1 PMID:17624297 -1.1.1.318 coniferyl acetate ocimum basilicum 0.004 0.004 1 PMID:27519164 -1.1.1.318 coniferyl acetate ocimum gratissimum 0.011 0.011 1 PMID:27519164 -1.1.1.318 coniferyl acetate ocimum kilimandscharicum 0.003 0.003 1 PMID:27519164 -1.1.1.318 coniferyl acetate ocimum tenuiflorum 0.028 0.028 1 PMID:27519164 -1.1.1.318 coniferyl acetate petunia x hybrida 0.6 0.6 1 PMID:18208524 -1.1.1.319 4-coumaryl acetate pimpinella anisum 0.07 0.07 1 PMID:18987218 -1.1.1.319 coniferyl acetate clarkia breweri 0.99 0.99 1 PMID:18208524 -1.1.1.319 coniferyl acetate daucus carota subsp. sativus 0.46 0.46 1 PMID:30634080 -1.1.1.319 coniferyl acetate petunia x hybrida 1.3 1.3 1 PMID:18208524 -1.1.1.319 coniferyl acetate pimpinella anisum 1.02 1.02 1 PMID:18987218 -1.1.1.319 nadph daucus carota subsp. sativus 0.68 0.68 1 PMID:30634080 -1.1.1.320 1-phenyl-1,2-propanedione bacillus cereus 2.75 2.75 1 PMID:11796169 -1.1.1.320 benzil bacillus cereus 1.07 1.07 1 PMID:11796169 -1.1.1.320 benzil ogataea glucozyma 0.14 0.14 1 PMID:26377422 -1.1.1.325 nadph chlorobaculum tepidum 5.0 5.0 1 * -1.1.1.325 sepiapterin chlorobaculum tepidum 5.0 5.0 1 * -1.1.1.326 10-hydroxy-alpha-humulene zingiber zerumbet 1.3 1.3 1 PMID:21668645 -1.1.1.326 nad+ zingiber zerumbet 3.8 3.8 1 PMID:21668645 -1.1.1.332 chanoclavine-i aspergillus fumigatus 0.38 0.38 1 PMID:20526482 -1.1.1.332 chanoclavine-i penicillium roqueforti 0.172 0.172 1 PMID:28902217 -1.1.1.332 chanoclavine-i trichophyton benhamiae 0.76 0.76 1 PMID:22403186 -1.1.1.332 nad+ penicillium roqueforti 0.135 0.135 1 PMID:28902217 -1.1.1.335 udp-2-acetamido-2-deoxy-alpha-d-glucuronate bordetella pertussis 0.0047 0.0043 2 PMID:21241053 -1.1.1.335 udp-2-acetamido-2-deoxy-alpha-d-glucuronate chromobacterium violaceum 0.00076 0.000535 2 PMID:21241053 -1.1.1.335 udp-alpha-d-glucuronate bordetella pertussis 0.0021 0.0021 1 PMID:21241053 -1.1.1.335 udp-alpha-d-glucuronate chromobacterium violaceum 0.00015 0.00015 1 PMID:21241053 -1.1.1.336 nad+ methanococcus maripaludis 0.4 0.4 1 PMID:18263721 -1.1.1.337 2-oxocaproate weissella confusa 360000.0 360000.0 1 PMID:8055963;PMID:9153075 -1.1.1.337 2-oxoisocaproate weissella confusa 2400.0 2400.0 1 PMID:9153075 -1.1.1.337 4-methyl-2-oxopentanoate weissella confusa 2400.0 2400.0 1 PMID:8055963 -1.1.1.337 nadh methanobrevibacter millerae 48.9 48.9 1 PMID:29234237 -1.1.1.337 oxo-tert-leucine weissella confusa 52.0 52.0 1 PMID:9153075 -1.1.1.337 phenylglyoxylate weissella confusa 18000.0 18000.0 1 PMID:9153075 -1.1.1.337 phenylpyruvate weissella confusa 7300.0 7300.0 1 PMID:8055963;PMID:9153075 -1.1.1.337 pyruvate weissella confusa 90.0 90.0 1 PMID:8055963;PMID:9153075 -1.1.1.337 sulfopyruvate methanobrevibacter millerae 62.8 62.8 1 PMID:29234237 -1.1.1.34 hydroxymethylglutaryl-coa rattus norvegicus 0.023 0.023 1 PMID:18446881 -1.1.1.340 1-deoxy-11beta-hydroxypentalenic acid streptomyces avermitilis 0.65 0.65 1 PMID:17178094 -1.1.1.343 6-phospho-d-gluconate gluconacetobacter diazotrophicus 3.63 2.3 2 PMID:32621793 -1.1.1.343 6-phospho-d-gluconate gluconobacter oxydans 23.0 23.0 1 PMID:20676631 -1.1.1.343 nad+ gluconacetobacter diazotrophicus 6.06 4.34 2 PMID:32621793 -1.1.1.343 nad+ neomoorella thermoacetica 12.6 12.6 1 PMID:27587230 -1.1.1.343 nad+ thermotoga maritima 23.3 23.3 1 PMID:27805055 -1.1.1.343 nadp+ gluconacetobacter diazotrophicus 2.8 2.27 2 PMID:32621793 -1.1.1.345 (r)-2-hydroxy-4-methylpentanoate lacticaseibacillus casei 43.0 43.0 1 * -1.1.1.345 2-hydroxyhexanoate lacticaseibacillus casei 26.0 26.0 1 * -1.1.1.345 2-hydroxyoctanoate lacticaseibacillus casei 15.0 15.0 1 * -1.1.1.345 2-hydroxypentanoate lacticaseibacillus casei 24.0 24.0 1 * -1.1.1.345 2-oxohexanoate lacticaseibacillus casei 139.0 139.0 1 * -1.1.1.345 2-oxooctanoate lacticaseibacillus casei 1200.0 1200.0 1 * -1.1.1.345 2-oxopentanoate lacticaseibacillus casei 197.0 197.0 1 * -1.1.1.345 3-(4-hydroxyphenyl)-2-oxopropanoate lacticaseibacillus casei 788.0 788.0 1 * -1.1.1.345 4-methyl-2-oxopentanoate lacticaseibacillus casei 84.0 84.0 1 * -1.1.1.345 phenylpyruvate lacticaseibacillus casei 968.0 968.0 1 * -1.1.1.345 phenylpyruvate lactobacillus delbrueckii subsp. bulgaricus 8.48 8.48 1 PMID:23110853 -1.1.1.346 2,5-didehydro-d-gluconate corynebacterium sp. 8.3 8.3 1 PMID:3597405 -1.1.1.346 ethyl 2-methylacetoacetate escherichia coli 2.6 2.6 1 PMID:11934293 -1.1.1.346 nadph corynebacterium sp. 18.3 18.3 1 PMID:12009883 -1.1.1.347 geraniol carpoglyphus lactis 2996.0 2996.0 1 PMID:18422649 -1.1.1.35 (3beta,5alpha,17beta)-androstane-3,17-diol homo sapiens 0.093 0.093 1 PMID:10329704 -1.1.1.35 (r)-3-hydroxyacyl-coa caenorhabditis elegans 45.0 45.0 1 PMID:24763278 -1.1.1.35 (s)-3-hydroxybutanoyl-coa metallosphaera sedula 15.0 15.0 1 PMID:24532060 -1.1.1.35 (s)-3-hydroxybutyryl-coa homo sapiens 1420.0 588.3 4 PMID:18036338 -1.1.1.35 (s)-3-hydroxybutyryl-coa mycobacterium tuberculosis 0.012 0.012 1 PMID:20378648 -1.1.1.35 17beta-estradiol homo sapiens 0.011 0.011 1 PMID:10329704 -1.1.1.35 3-acetoacetyl-coa clostridium acetobutylicum 13000.0 13000.0 1 PMID:30387779 -1.1.1.35 3-acetoacetyl-coa mycobacterium tuberculosis 0.011 0.011 1 PMID:20378648 -1.1.1.35 3-acetoacyl-coa cupriavidus necator 104.0 94.0 2 PMID:30243533 -1.1.1.35 3-ketohexadecanoyl-coa sus scrofa 45.0 45.0 1 PMID:9593854 -1.1.1.35 3-ketohexdecanoyl-coa homo sapiens 24.0 24.0 1 PMID:9553139 -1.1.1.35 3-ketooctanoyl-coa homo sapiens 28.0 28.0 1 PMID:9553139 -1.1.1.35 3-ketooctanoyl-coa sus scrofa 102.0 102.0 1 PMID:9593854 -1.1.1.35 3-oxohexanoyl-coa cupriavidus necator 43.0 41.5 2 PMID:30243533 -1.1.1.35 3-oxooctanoyl-coa cupriavidus necator 53.0 32.0 2 PMID:30243533 -1.1.1.35 acetoacetyl-coa cupriavidus necator 45500.0 45500.0 1 PMID:24792376 -1.1.1.35 acetoacetyl-coa homo sapiens 1287.0 155.0 9 PMID:10231530;PMID:18036338;PMID:9553139 -1.1.1.35 acetoacetyl-coa rattus norvegicus 569.0 569.0 1 PMID:15358356 -1.1.1.35 acetoacetyl-coa sus scrofa 330.0 330.0 1 PMID:9593854 -1.1.1.35 androsterone homo sapiens 0.011 0.011 1 PMID:10329704 -1.1.1.35 nad+ homo sapiens 1817.0 1261.0 2 PMID:18036338 -1.1.1.35 nad+ mycobacterium tuberculosis 0.004 0.004 1 PMID:20378648 -1.1.1.35 nadh clostridium acetobutylicum 8500.0 8500.0 1 PMID:30387779 -1.1.1.35 nadh homo sapiens 510.0 343.35 2 PMID:18036338 -1.1.1.35 nadh mycobacterium tuberculosis 0.189 0.189 1 PMID:20378648 -1.1.1.350 (s)-ureidoglycolate escherichia coli 57.06 57.06 1 PMID:23284870 -1.1.1.350 nad+ escherichia coli 62.39 62.39 1 PMID:23284870 -1.1.1.351 6-phospho-d-gluconate thermotoga maritima 325.0 325.0 1 PMID:19497097 -1.1.1.354 geraniol carpoglyphus lactis 2996.0 2996.0 1 PMID:18422649 -1.1.1.357 (r)-tetralol homo sapiens 0.18 0.18 1 PMID:11104674 -1.1.1.357 (s)-1,2,3,4-tetrahydronaphth-1-ol homo sapiens 0.27 0.23500000000000001 2 PMID:9716498 -1.1.1.357 (s)-indan-1-ol homo sapiens 0.18 0.16 3 PMID:11104674;PMID:9716498 -1.1.1.357 (s)-tetralol homo sapiens 0.2 0.2 1 PMID:11104674 -1.1.1.357 2-decalol comamonas testosteroni 4.3 2.2 3 PMID:28137513;PMID:30794798 -1.1.1.357 3alpha-androstanediol homo sapiens 0.035 0.035 1 PMID:10998348 -1.1.1.357 4-androstenedione homo sapiens 0.0038 0.0038 1 PMID:31733346 -1.1.1.357 4-hydroxyandrostenedione homo sapiens 0.032 0.02075 4 PMID:31733346 -1.1.1.357 4-hydroxytestosterone homo sapiens 0.025 0.01 3 PMID:31733346 -1.1.1.357 5alpha-androstan-17-beta-ol-3-one oryctolagus cuniculus 0.367 0.367 1 PMID:25660042 -1.1.1.357 5alpha-androstan-3alpha-ol-17-one homo sapiens 0.007 0.007 2 PMID:9716498 -1.1.1.357 5alpha-androstane-3,17-dione homo sapiens 0.03 0.03 1 PMID:10998348 -1.1.1.357 5alpha-androstane-3alpha,17beta-diol homo sapiens 0.087 0.087 1 PMID:11104674 -1.1.1.357 5alpha-dihydroprogesterone homo sapiens 0.003 0.003 1 PMID:12416991 -1.1.1.357 5alpha-dihydrotestosterone homo sapiens 0.0612 0.0471 2 PMID:10998348;PMID:24434280 -1.1.1.357 5alpha-pregnan-20alpha-ol-3-one oryctolagus cuniculus 0.05 0.05 1 PMID:25660042 -1.1.1.357 5beta-androstan-3,17-dione oryctolagus cuniculus 0.14 0.14 1 PMID:25660042 -1.1.1.357 5beta-androstan-3alpha-ol-17-one homo sapiens 0.048 0.048 1 PMID:11104674 -1.1.1.357 5beta-androstan-3alpha-ol-17-one oryctolagus cuniculus 0.113 0.113 1 PMID:25660042 -1.1.1.357 5beta-androstane-3alpha,17beta-diol homo sapiens 0.047 0.047 1 PMID:11104674 -1.1.1.357 5beta-pregnane-3,20-dione oryctolagus cuniculus 0.053 0.053 1 PMID:25660042 -1.1.1.357 5beta-pregnane-3alpha,20alpha-diol homo sapiens 0.003 0.0025 2 PMID:9716498 -1.1.1.357 9alpha,11beta-prostaglandin f2 homo sapiens 0.42 0.2515 2 PMID:9716498 -1.1.1.357 allopregnanolone homo sapiens 1.7e-05 1.7e-05 1 PMID:12416991 -1.1.1.357 androstenol comamonas testosteroni 230.0 230.0 1 PMID:28137513 -1.1.1.357 androsterone comamonas testosteroni 500.0 253.6 2 PMID:28137513;PMID:30794798 -1.1.1.357 androsterone homo sapiens 0.043 0.033 2 PMID:10998348;PMID:11104674 -1.1.1.357 chenodeoxycholic acid homo sapiens 0.032 0.032 1 PMID:11104674 -1.1.1.357 cholic acid homo sapiens 0.2 0.2 1 PMID:11104674 -1.1.1.357 cholic acid pseudomonas sp. b-0831 23.0 23.0 1 PMID:29912635 -1.1.1.357 cyclohexanol comamonas testosteroni 2.5 1.62 2 PMID:28137513;PMID:30794798 -1.1.1.357 dehydrocholic acid pseudomonas sp. b-0831 48.0 48.0 1 PMID:29912635 -1.1.1.357 dehydrolithocholic acid oryctolagus cuniculus 0.037 0.037 1 PMID:25660042 -1.1.1.357 deoxycholic acid homo sapiens 0.085 0.085 1 PMID:11104674 -1.1.1.357 dihydrotestosterone homo sapiens 0.026 0.023 5 PMID:11514561;PMID:31733346 -1.1.1.357 lithocholic acid homo sapiens 0.032 0.032 1 PMID:11104674 -1.1.1.357 nad+ homo sapiens 0.2 0.2 1 PMID:11104674 -1.1.1.357 nadp+ homo sapiens 0.04 0.04 1 PMID:11104674 -1.1.1.357 nadp+ oryctolagus cuniculus 0.85 0.85 1 PMID:25660042 -1.1.1.357 nadph oryctolagus cuniculus 0.077 0.077 1 PMID:25660042 -1.1.1.357 pregn-4-en-3,20-dione homo sapiens 0.0035 0.0035 1 PMID:24434280 -1.1.1.357 testosterone homo sapiens 0.032 0.032 1 PMID:31733346 -1.1.1.358 2-dehydropantolactone candida dubliniensis 59.0 59.0 3 PMID:31000167 -1.1.1.359 beta-d-glucose saccharolobus solfataricus 75.0 61.45 6 PMID:12824170;PMID:16556607;PMID:21265750 -1.1.1.359 d-galactose saccharolobus solfataricus 61.3 49.2 6 PMID:12824170;PMID:16556607;PMID:21265750 -1.1.1.359 d-xylose saccharolobus solfataricus 61.0 54.0 4 PMID:16556607;PMID:21265750 -1.1.1.359 l-arabinose saccharolobus solfataricus 41.0 41.0 1 PMID:21265750 -1.1.1.36 (3r)-3-hydroxydecanoyl-coa candida tropicalis 53.0 33.0 3 PMID:10497229 -1.1.1.36 (3r)-hydroxybutyryl-coa candida tropicalis 31.0 30.0 2 PMID:10497229 -1.1.1.36 (3r)-hydroxyhexadecanoyl-coa candida tropicalis 41.0 12.0 3 PMID:10497229 -1.1.1.36 2-methylacetoacetyl-coa zoogloea ramigera 27.0 27.0 1 PMID:3286259 -1.1.1.36 acetoacetyl-coa candidatus accumulibacter phosphatis 11.6 5.8655 2 PMID:33122026 -1.1.1.36 acetoacetyl-coa homo sapiens 0.5 0.5 1 PMID:25577493 -1.1.1.36 acetoacetyl-coa zoogloea ramigera 300.0 300.0 1 PMID:3286259 -1.1.1.36 acetoacetyl-s-(d-pantetheine)11-pivalate zoogloea ramigera 267.0 267.0 1 PMID:3286259 -1.1.1.36 butyrylacetyl-coa zoogloea ramigera 9.0 9.0 1 PMID:3286259 -1.1.1.36 d-3-hydroxybutyryl-coa zoogloea ramigera 90.0 90.0 1 PMID:3286259 -1.1.1.36 nadh candidatus accumulibacter phosphatis 8.92 8.92 1 PMID:33122026 -1.1.1.36 nadph candidatus accumulibacter phosphatis 0.095 0.095 1 PMID:33122026 -1.1.1.36 propionylacetyl-coa zoogloea ramigera 124.0 124.0 1 PMID:3286259 -1.1.1.361 d-glucose 6-phosphate bacillus subtilis 5.8 4.1 4 PMID:28353336;PMID:32786294 -1.1.1.361 nad+ bacillus subtilis 5.8 4.1 4 PMID:28353336;PMID:32786294 -1.1.1.363 d-glucose 6-phosphate leuconostoc mesenteroides 1125.0 823.5 4 PMID:1304341;PMID:8579362 -1.1.1.363 d-glucose 6-phosphate sphingomonas sp. pamc 26621 134.7 81.65 4 PMID:30889888 -1.1.1.363 nad+ leuconostoc mesenteroides 1125.0 1125.0 1 PMID:1304341 -1.1.1.363 nad+ pseudomonas putida 277.0 277.0 1 PMID:26702395 -1.1.1.363 nadh pseudomonas putida 254.0 254.0 1 PMID:26702395 -1.1.1.363 nadp+ leuconostoc mesenteroides 522.0 522.0 1 PMID:1304341 -1.1.1.363 nadp+ pseudomonas putida 102.0 102.0 1 PMID:26702395 -1.1.1.363 nadph pseudomonas putida 105.0 105.0 1 PMID:26702395 -1.1.1.365 d-galacturonate aspergillus niger 6.88 6.165 2 PMID:18768163 -1.1.1.365 d-galacturonate euglena gracilis 0.19 0.19 1 PMID:17090924 -1.1.1.365 d-glucuronate aspergillus niger 3.11 1.6199999999999999 2 PMID:18768163 -1.1.1.365 d-glucuronate euglena gracilis 0.19 0.19 1 PMID:17090924 -1.1.1.365 d-xylose euglena gracilis 0.06 0.06 1 PMID:17090924 -1.1.1.365 l-galactonate aspergillus niger 0.16 0.12 2 PMID:18768163 -1.1.1.365 nadh aspergillus niger 4.98 4.98 1 PMID:18768163 -1.1.1.365 nadph aspergillus niger 7.11 7.11 1 PMID:18768163 -1.1.1.366 5-dehydro-d-gluconate aspergillus niger 7.2 7.2 1 PMID:28261181 -1.1.1.366 l-idonate aspergillus niger 5.5 5.5 1 PMID:28261181 -1.1.1.368 6-hydroxycyclohex-1-ene-1-carbonyl-coa thauera aromatica 7.0 7.0 1 PMID:10406950 -1.1.1.369 1d-chiro-inositol thermotoga maritima 1.0 1.0 1 PMID:23441918 -1.1.1.37 (s)-malate flavobacterium frigidimaris 138.0 65.8 4 PMID:16306697 -1.1.1.37 (s)-malate malus domestica 9.91 9.155000000000001 2 PMID:20934777 -1.1.1.37 (s)-malate methylosinus trichosporium 1141.0 1141.0 1 PMID:27682078 -1.1.1.37 (s)-malate methylotuvimicrobium alcaliphilum 621.0 621.0 1 PMID:27682078 -1.1.1.37 (s)-malate mycobacterium tuberculosis 302.0 302.0 1 PMID:25860441 -1.1.1.37 (s)-malate streptomyces coelicolor 4.71 4.71 1 PMID:21071865 -1.1.1.37 (s)-malate sus scrofa 18.0 18.0 1 PMID:21114258 -1.1.1.37 (s)-malate synechocystis sp. pcc 6803 0.43 0.43 1 PMID:30057585 -1.1.1.37 (s)-malate taenia solium 47.4 47.2 2 PMID:21439955 -1.1.1.37 3-acetylpyridine-adenine dinucleotide plasmodium falciparum 7300.0 7300.0 1 PMID:19184366 -1.1.1.37 acetylpyridine adenine dinucleotide plasmodium falciparum 1010.0 1010.0 1 PMID:15317584 -1.1.1.37 alpha-ketomalonate plasmodium falciparum 674.0 674.0 1 PMID:15317584 -1.1.1.37 l-malate rasamsonia emersonii 3500.0 3200.0 2 PMID:15265031 -1.1.1.37 l-malate sus scrofa 76.7 76.7 1 PMID:215188 -1.1.1.37 malate plasmodium falciparum 250.0 250.0 1 PMID:15317584 -1.1.1.37 malate triticum aestivum 4729.0 4729.0 1 PMID:15388227 -1.1.1.37 nad+ flavobacterium frigidimaris 139.0 48.6 5 PMID:16306697 -1.1.1.37 nad+ malus domestica 3.21 2.875 2 PMID:20934777 -1.1.1.37 nad+ mycobacterium tuberculosis 320.0 320.0 1 PMID:25860441 -1.1.1.37 nad+ plasmodium falciparum 150.0 150.0 1 PMID:15317584 -1.1.1.37 nad+ rasamsonia emersonii 3100.0 2935.0 2 PMID:15265031 -1.1.1.37 nad+ streptomyces coelicolor 3.66 3.66 1 PMID:21071865 -1.1.1.37 nad+ synechocystis sp. pcc 6803 0.21 0.21 1 PMID:30057585 -1.1.1.37 nad+ taenia solium 385.6 385.3 2 PMID:21439955 -1.1.1.37 nadh arabidopsis thaliana 677.0 510.0 2 PMID:29194485 -1.1.1.37 nadh malus domestica 609.5 609.5 1 PMID:20934777 -1.1.1.37 nadh metallosphaera sedula 0.02 0.02 1 PMID:30638660 -1.1.1.37 nadh mycobacterium tuberculosis 3330.0 3330.0 1 PMID:25860441 -1.1.1.37 nadh plasmodium falciparum 7880.0 4415.0 2 PMID:15317584;PMID:19184366 -1.1.1.37 nadh rasamsonia emersonii 110000.0 100000.0 2 PMID:15265031 -1.1.1.37 nadh streptomyces coelicolor 542.0 542.0 1 PMID:21071865 -1.1.1.37 nadh synechocystis sp. pcc 6803 0.97 0.97 1 PMID:30057585 -1.1.1.37 nadh taenia solium 962.7 962.35 2 PMID:21439955 -1.1.1.37 nadph metallosphaera sedula 0.01 0.01 1 PMID:30638660 -1.1.1.37 oxaloacetate arabidopsis thaliana 608.0 479.5 2 PMID:29194485 -1.1.1.37 oxaloacetate escherichia coli 931.0 931.0 1 PMID:17947381 -1.1.1.37 oxaloacetate haloarcula marismortui 197.0 103.0 2 PMID:8476859 -1.1.1.37 oxaloacetate ignicoccus islandicus 444.0 444.0 1 PMID:31301348 -1.1.1.37 oxaloacetate malus domestica 4553.0 4553.0 1 PMID:20934777 -1.1.1.37 oxaloacetate methylorubrum extorquens 460.0 460.0 1 PMID:30279311 -1.1.1.37 oxaloacetate methylosinus trichosporium 516.0 516.0 1 PMID:27682078 -1.1.1.37 oxaloacetate methylotuvimicrobium alcaliphilum 870.0 870.0 1 PMID:27682078 -1.1.1.37 oxaloacetate moritella sp. 0.00483 0.004345 2 PMID:15043884 -1.1.1.37 oxaloacetate mycobacterium tuberculosis 2437.0 2437.0 1 PMID:25860441 -1.1.1.37 oxaloacetate plasmodium falciparum 8570.0 4765.0 2 PMID:15317584;PMID:19184366 -1.1.1.37 oxaloacetate pyrobaculum calidifontis 77.0 77.0 1 PMID:26507956 -1.1.1.37 oxaloacetate rasamsonia emersonii 91000.0 86000.0 2 PMID:15265031 -1.1.1.37 oxaloacetate streptomyces coelicolor 1870.0 1870.0 1 PMID:21071865 -1.1.1.37 oxaloacetate sulfolobus acidocaldarius 2.62 2.62 1 PMID:3109450 -1.1.1.37 oxaloacetate sus scrofa 377.0 377.0 1 PMID:21114258 -1.1.1.37 oxaloacetate synechocystis sp. pcc 6803 0.71 0.71 1 PMID:30057585 -1.1.1.37 oxaloacetate taenia solium 665.3 665.15 2 PMID:21439955 -1.1.1.37 oxaloacetate thermoplasma acidophilum 1.8 1.8 1 PMID:3741624 -1.1.1.37 oxaloacetate triticum aestivum 121600.0 121600.0 1 PMID:15388227 -1.1.1.37 pyruvate ignicoccus islandicus 8.0 8.0 1 PMID:31301348 -1.1.1.37 reduced acetylpyridine adenine dinucleotide plasmodium falciparum 175.0 175.0 1 PMID:15317584 -1.1.1.370 l-epi-2-inosose paracoccus laeviglucosivorans 75.0 75.0 1 PMID:29799855 -1.1.1.370 myo-inositol paracoccus laeviglucosivorans 9.53 9.53 1 PMID:29799855 -1.1.1.370 scyllo-inositol paracoccus laeviglucosivorans 11.75 11.75 1 PMID:29799855 -1.1.1.373 (s)-3-sulfolactaldehyde escherichia coli 332.0 332.0 1 * -1.1.1.373 2-hydroxy-3-oxopropane-1-sulfonate escherichia coli 332.0 332.0 1 * -1.1.1.373 nadh escherichia coli 548.0 548.0 2 * -1.1.1.374 nad+ methanococcus maripaludis 0.99 0.99 1 PMID:18634748 -1.1.1.374 udp-n-acetyl-alpha-d-glucosamine methanococcus maripaludis 0.9 0.9 1 PMID:18634748 -1.1.1.376 d-fucose rhizobium leguminosarum bv. trifolii 120.4 115.25 2 PMID:25236800 -1.1.1.376 d-galactose azospirillum brasilense 26.0 22.9 2 PMID:16326697 -1.1.1.376 d-galactose rhizobium leguminosarum bv. trifolii 69.9 54.010000000000005 2 PMID:25236800 -1.1.1.376 d-talose azospirillum brasilense 9.7 5.369999999999999 2 PMID:16326697 -1.1.1.376 d-talose rhizobium leguminosarum bv. trifolii 99.52 87.05 2 PMID:25236800 -1.1.1.376 d-xylose azospirillum brasilense 12.0 8.0 2 PMID:16326697 -1.1.1.376 l-arabinose azospirillum brasilense 33.3 24.75 6 PMID:16326697;PMID:32828286 -1.1.1.376 l-arabinose rhizobium leguminosarum bv. trifolii 65.55 43.2 2 PMID:25236800 -1.1.1.376 nad+ azospirillum brasilense 105.9 48.7 3 PMID:31058311;PMID:32828286 -1.1.1.376 nad+ rhizobium leguminosarum bv. trifolii 85.73 85.73 1 PMID:25236800 -1.1.1.376 nadp+ azospirillum brasilense 66.7 66.7 3 PMID:31058311;PMID:32828286 -1.1.1.376 nadp+ rhizobium leguminosarum bv. trifolii 35.45 35.45 1 PMID:25236800 -1.1.1.377 l-lyxose thermoplasma acidophilum 23.77 23.77 1 PMID:22481639 -1.1.1.377 l-mannose thermoplasma acidophilum 14.88 14.88 1 PMID:22481639 -1.1.1.377 l-rhamnose thermoplasma acidophilum 22.36 22.36 1 PMID:22481639 -1.1.1.377 nadp+ thermoplasma acidophilum 18.08 17.1 3 PMID:22481639 -1.1.1.378 l-fucose azotobacter vinelandii 9.2 7.0 2 PMID:18505728 -1.1.1.378 l-lyxose azotobacter vinelandii 85.3 79.7 3 PMID:18505728;PMID:33482017 -1.1.1.378 l-mannose azotobacter vinelandii 46.3 17.0 3 PMID:18505728;PMID:33482017 -1.1.1.378 l-rhamnose azotobacter vinelandii 83.5 74.8 3 PMID:18505728;PMID:33482017 -1.1.1.378 nad+ azotobacter vinelandii 66.0 66.0 1 PMID:33482017 -1.1.1.378 nadp+ azotobacter vinelandii 54.8 54.8 1 PMID:33482017 -1.1.1.379 (r)-mandelate schleiferilactobacillus harbinensis 30.28 30.28 1 PMID:29460618 -1.1.1.379 nad+ schleiferilactobacillus harbinensis 29.05 29.05 1 PMID:29460618 -1.1.1.38 (s)-malate escherichia coli k-12 134.4 134.4 1 PMID:17215140 -1.1.1.38 (s)-malate homo sapiens 55.0 49.0 2 PMID:24998673 -1.1.1.38 l-malate ascaris suum 130.0 130.0 1 PMID:9179290 -1.1.1.38 nad+ escherichia coli 57.3 57.3 1 PMID:33523590 -1.1.1.38 nicotinamide cytosine dinucleotide escherichia coli 26.1 26.1 1 PMID:33523590 -1.1.1.38 oxaloacetate ascaris suum 30.0 29.0 2 PMID:3741834 -1.1.1.38 pyruvate ascaris suum 0.09 0.075 2 PMID:3741834 -1.1.1.380 l-gulonate halomonas elongata 1.8 1.8 1 PMID:25145794 -1.1.1.381 d-3-hydroxyisobutyrate escherichia coli 3.78 3.78 1 PMID:12535615 -1.1.1.381 d-3-hydroxyisobutyrate saccharomyces cerevisiae 8.61 8.61 1 PMID:12535615 -1.1.1.381 d-glycerate escherichia coli 2.01 2.01 1 PMID:12535615 -1.1.1.381 d-serine escherichia coli 3.5 3.5 1 PMID:12535615 -1.1.1.381 d-serine saccharomyces cerevisiae 7.84 7.84 1 PMID:12535615 -1.1.1.381 d-threonine escherichia coli 6.55 6.55 1 PMID:12535615 -1.1.1.381 d-threonine saccharomyces cerevisiae 52.8 52.8 1 PMID:12535615 -1.1.1.381 l-3-hydroxybutyrate saccharomyces cerevisiae 9.38 9.38 1 PMID:12535615 -1.1.1.381 l-3-hydroxyisobutyrate escherichia coli 4.03 4.03 1 PMID:12535615 -1.1.1.381 l-3-hydroxyisobutyrate saccharomyces cerevisiae 20.1 20.1 1 PMID:12535615 -1.1.1.381 l-allo-threonine escherichia coli 5.76 5.76 1 PMID:12535615 -1.1.1.381 l-allo-threonine saccharomyces cerevisiae 43.8 43.8 1 PMID:12535615 -1.1.1.381 l-glycerate escherichia coli 1.17 1.17 1 PMID:12535615 -1.1.1.381 l-serine escherichia coli 4.2 4.2 1 PMID:12535615 -1.1.1.381 l-serine saccharomyces cerevisiae 11.0 11.0 1 PMID:12535615 -1.1.1.382 nadh archaeoglobus fulgidus 0.1 0.1 1 PMID:25172159 -1.1.1.382 nadh desulfosudis oleivorans 0.25 0.25 1 PMID:25172159 -1.1.1.382 nadh thermacetogenium phaeum 0.46 0.46 1 PMID:25172159 -1.1.1.382 nadh uncultured archaeon 0.22 0.22 1 PMID:25172159 -1.1.1.383 nadh escherichia coli 0.3 0.3 2 PMID:21515217;PMID:23776225 -1.1.1.383 nadh hydrogenobaculum sp. y04aas1 0.12 0.12 1 PMID:25172159 -1.1.1.383 nadh ignisphaera aggregans 0.02 0.02 1 PMID:25172159 -1.1.1.383 nadh lactococcus lactis subsp. lactis 0.1 0.1 1 PMID:23776225 -1.1.1.383 nadh metallosphaera sedula 0.06 0.06 1 PMID:25172159 -1.1.1.383 nadh shewanella sp. 1.1 1.1 1 PMID:23776225 -1.1.1.383 nadh slackia exigua 0.41 0.41 1 PMID:23776225 -1.1.1.383 nadph escherichia coli 3.6 3.6 2 PMID:21515217;PMID:23776225 -1.1.1.383 nadph hydrogenobaculum sp. y04aas1 0.12 0.12 1 PMID:25172159 -1.1.1.383 nadph ignisphaera aggregans 0.03 0.03 1 PMID:25172159 -1.1.1.383 nadph lactococcus lactis subsp. lactis 0.8 0.8 1 PMID:23776225 -1.1.1.383 nadph metallosphaera sedula 0.07 0.07 1 PMID:25172159 -1.1.1.383 nadph shewanella sp. 4.5 4.5 1 PMID:23776225 -1.1.1.383 nadph slackia exigua 0.8 0.8 1 PMID:23776225 -1.1.1.387 d-glycerate pseudomonas aeruginosa 5.8 5.8 1 PMID:22128181 -1.1.1.387 dl-threonine pseudomonas aeruginosa 9.6 9.6 1 PMID:22128181 -1.1.1.387 l-serine pseudomonas aeruginosa 10.4 10.4 1 PMID:22128181 -1.1.1.387 methyl 2,2-dimethyl-3-hydroxypropionate pseudomonas aeruginosa 11.6 11.6 1 PMID:22128181 -1.1.1.387 nad+ pseudomonas aeruginosa 1.6 1.6 1 PMID:22128181 -1.1.1.388 d-glucose 6-phosphate haloferax volcanii 5.4 5.4 1 PMID:25836736 -1.1.1.388 nad+ haloferax volcanii 0.18 0.18 1 PMID:25836736 -1.1.1.39 (s)-malate arabidopsis thaliana 46.0 41.55 6 PMID:18223148;PMID:20133948;PMID:20528775 -1.1.1.39 (s)-malate rhodopseudomonas palustris 770.0 625.0 2 PMID:20057150 -1.1.1.39 (s)-malate solanum tuberosum 617.0 617.0 1 PMID:7294802 -1.1.1.39 nad+ arabidopsis thaliana 46.0 41.55 4 PMID:20133948;PMID:20528775 -1.1.1.39 nad+ rhodopseudomonas palustris 720.0 720.0 1 PMID:20057150 -1.1.1.39 nadp+ rhodopseudomonas palustris 520.0 520.0 1 PMID:20057150 -1.1.1.390 sulfoquinovose pseudomonas putida 33.8 17.599999999999998 2 PMID:26195800 -1.1.1.391 12alpha-hydroxy-3-oxo-5-beta-cholan-24-oic acid eggerthella lenta 29.71 19.72 2 PMID:26192599 -1.1.1.391 3beta,7alpha-dihydroxy-5beta-cholan-24-oic acid homo sapiens 0.022 0.022 1 PMID:10733557 -1.1.1.391 3beta,7beta-dihydroxy-5beta-cholan-24-oic acid homo sapiens 0.033 0.033 1 PMID:10733557 -1.1.1.391 3beta-hydroxy-5beta-cholan-24-oic acid homo sapiens 0.047 0.031 2 PMID:10733557 -1.1.1.392 12alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid eggerthella lenta 4.85 4.85 1 PMID:26192599 -1.1.1.393 12alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid mediterraneibacter gnavus 157.2 157.2 1 PMID:26192599 -1.1.1.395 3-oxochenodeoxycholoyl-coa [clostridium] scindens 0.4 0.28500000000000003 2 PMID:23836456 -1.1.1.395 3-oxocholoyl-coa [clostridium] scindens 0.55 0.34500000000000003 2 PMID:23836456 -1.1.1.395 3-oxodeoxycholoyl-coa [clostridium] scindens 0.73 0.44 2 PMID:23836456 -1.1.1.395 3-oxolithocholoyl-coa [clostridium] scindens 0.7 0.41 2 PMID:23836456 -1.1.1.395 chenodeoxycholic acid [clostridium] scindens 0.25 0.1525 2 PMID:23836456 -1.1.1.395 chenodeoxycholoyl-coa [clostridium] scindens 0.82 0.51 2 PMID:23836456 -1.1.1.395 cholic acid [clostridium] scindens 0.27 0.18 2 PMID:23836456 -1.1.1.395 choloyl-coa [clostridium] scindens 1.23 0.7 2 PMID:23836456 -1.1.1.395 deoxycholoyl-coa [clostridium] scindens 0.87 0.515 2 PMID:23836456 -1.1.1.395 glycocholic acid [clostridium] scindens 0.42 0.2825 2 PMID:23836456 -1.1.1.395 lithocholoyl-coa [clostridium] scindens 0.73 0.45499999999999996 2 PMID:23836456 -1.1.1.395 nad+ [clostridium] scindens 0.3 0.1945 2 PMID:23836456 -1.1.1.395 nadp+ [clostridium] scindens 0.11 0.0675 2 PMID:23836456 -1.1.1.395 taurocholic acid [clostridium] scindens 0.4 0.275 2 PMID:23836456 -1.1.1.399 2-oxoglutarate escherichia coli 33.3 33.3 1 PMID:8550422 -1.1.1.4 (2r,3r)-2,3-butanediol clostridium autoethanogenum 2.1 2.1 1 PMID:24657865 -1.1.1.4 (2r,3r)-butane-2,3-diol klebsiella pneumoniae 5.8 4.81 2 PMID:24429283 -1.1.1.4 (2r,3r)-butane-2,3-diol rhodococcus erythropolis 4.28 4.28 1 PMID:25903366 -1.1.1.4 (3r,3s)-butane-2,3-diol klebsiella pneumoniae 10.38 7.03 2 PMID:24429283 -1.1.1.4 (r)-acetoin clostridium autoethanogenum 150.0 150.0 1 PMID:26034298 -1.1.1.4 2-butanone clostridium autoethanogenum 37.0 37.0 1 PMID:26034298 -1.1.1.4 acetaldehyde clostridium autoethanogenum 93.0 93.0 1 PMID:24657865 -1.1.1.4 acetaldehyde saccharomyces cerevisiae 96.62 33.3 4 PMID:32556414 -1.1.1.4 acetoin clostridium autoethanogenum 145.0 145.0 1 PMID:24657865 -1.1.1.4 acetoin escherichia coli 1.4 0.95 2 PMID:27931827 -1.1.1.4 acetone clostridium autoethanogenum 55.0 53.2 2 PMID:24657865;PMID:26034298 -1.1.1.4 butanone clostridium autoethanogenum 44.0 44.0 1 PMID:24657865 -1.1.1.4 diacetyl rhodococcus erythropolis 6.11 6.11 1 PMID:25903366 -1.1.1.4 glycerol klebsiella pneumoniae 18.88 14.695 2 PMID:24429283 -1.1.1.4 glycolaldehyde saccharomyces cerevisiae 53.46 23.375 4 PMID:32556414 -1.1.1.4 meso-butane-2,3-diol klebsiella pneumoniae 15.33 10.0 2 PMID:24429283 -1.1.1.4 nad+ rhodococcus erythropolis 10.27 10.27 1 PMID:25903366 -1.1.1.4 nadh rhodococcus erythropolis 5.73 5.73 1 PMID:25903366 -1.1.1.4 nadph clostridium autoethanogenum 68.0 68.0 1 PMID:26034298 -1.1.1.40 (s)-malate arabidopsis thaliana 324.1 268.05 6 PMID:18288573;PMID:19725876 -1.1.1.40 (s)-malate azospirillum brasilense 327.0 327.0 1 PMID:32485238 -1.1.1.40 (s)-malate columba livia 34.83 23.17 4 PMID:16889632 -1.1.1.40 (s)-malate columba sp. 140.1 140.1 1 PMID:18248329 -1.1.1.40 (s)-malate homo sapiens 110.9 30.0 3 PMID:19416979;PMID:24998673 -1.1.1.40 (s)-malate leishmania major 113.63 113.63 1 PMID:29128656 -1.1.1.40 (s)-malate leishmania mexicana 122.23 122.23 1 PMID:29128656 -1.1.1.40 (s)-malate methylosinus trichosporium 0.3 0.3 1 PMID:31228930 -1.1.1.40 (s)-malate nicotiana tabacum 177.0 165.65 2 PMID:18272530 -1.1.1.40 (s)-malate oryza sativa 181.6 96.7 3 PMID:16290176;PMID:23228551 -1.1.1.40 (s)-malate populus trichocarpa 19.1 13.6 5 PMID:23096088 -1.1.1.40 (s)-malate saccharolobus solfataricus 376.0 376.0 1 PMID:3108257 -1.1.1.40 (s)-malate sorghum bicolor 275.7 275.7 1 PMID:23228551 -1.1.1.40 (s)-malate trypanosoma brucei 1132.0 687.0 4 PMID:21105905 -1.1.1.40 (s)-malate trypanosoma cruzi 683.0 600.5 4 PMID:21105905 -1.1.1.40 (s)-malate zea mays 269.0 91.0 9 PMID:17150960;PMID:22514092;PMID:23228551;PMID:31235877 -1.1.1.40 l-malate anas platyrhynchos 160.0 160.0 1 PMID:1622402 -1.1.1.40 l-malate sinorhizobium meliloti 582.0 582.0 1 PMID:10407149 -1.1.1.40 nad+ homo sapiens 51.0 34.18 3 PMID:18959763;PMID:19091740;PMID:21980421 -1.1.1.40 nad+ thermococcus kodakarensis 4.69 4.69 1 PMID:23932397 -1.1.1.40 nad+ zea mays 13.5 13.5 2 PMID:12562758;PMID:15245332 -1.1.1.40 nadp+ arabidopsis thaliana 4670.0 268.1 5 PMID:16113210 -1.1.1.40 nadp+ escherichia coli 66.6 66.6 1 PMID:17557829 -1.1.1.40 nadp+ homo sapiens 135.8 126.0 3 PMID:18959763;PMID:19091740;PMID:21980421 -1.1.1.40 nadp+ leishmania major 119.89 119.89 1 PMID:29128656 -1.1.1.40 nadp+ leishmania mexicana 106.93 106.93 1 PMID:29128656 -1.1.1.40 nadp+ oryza sativa 98.3 93.3 2 PMID:16290176 -1.1.1.40 nadp+ populus trichocarpa 19.5 14.2 5 PMID:23096088 -1.1.1.40 nadp+ thermococcus kodakarensis 31.1 31.1 1 PMID:23932397 -1.1.1.40 nadp+ trypanosoma brucei 1206.0 745.0 4 PMID:21105905 -1.1.1.40 nadp+ trypanosoma cruzi 691.0 597.5 4 PMID:21105905 -1.1.1.40 nadp+ zea mays 269.0 60.9 12 PMID:12562758;PMID:15245332;PMID:22514092;PMID:31363039 -1.1.1.40 pyruvate arabidopsis thaliana 284.1 156.0 6 PMID:18288573;PMID:19725876 -1.1.1.40 pyruvate azospirillum brasilense 3.0 3.0 1 PMID:32485238 -1.1.1.40 pyruvate methylosinus trichosporium 0.067 0.067 1 PMID:31228930 -1.1.1.40 pyruvate nicotiana tabacum 158.4 90.0 2 PMID:18272530 -1.1.1.40 pyruvate trypanosoma brucei 113.0 73.5 4 PMID:21105905 -1.1.1.40 pyruvate trypanosoma cruzi 39.0 23.65 4 PMID:21105905 -1.1.1.401 2-dehydro-3-deoxy-l-lyxonate sphingomonas sp. 0.18 0.18 1 PMID:19187228 -1.1.1.401 2-dehydro-3-deoxy-l-mannonate sphingomonas sp. 0.012 0.012 1 PMID:19187228 -1.1.1.401 2-dehydro-3-deoxy-l-rhamnonate sphingomonas sp. 0.86 0.86 1 PMID:19187228 -1.1.1.404 2,6-dichloroindophenol sphingobium chlorophenolicum 14.1 14.1 1 PMID:23676275 -1.1.1.404 cytochrome c sphingobium chlorophenolicum 9.1 9.1 1 PMID:23676275 -1.1.1.404 nadh sphingobium chlorophenolicum 20.1 20.1 1 PMID:23676275 -1.1.1.404 nadph sphingobium chlorophenolicum 3.7 3.7 1 PMID:23676275 -1.1.1.405 (2r,3r)-2,3-dihydroxy-4-oxobutyl-phosphate haemophilus influenzae 0.5 0.5 1 PMID:11305920 -1.1.1.405 d-arabinose 5-phosphate haemophilus influenzae 2.3 2.3 1 PMID:11305920 -1.1.1.405 d-ribose 5-phosphate haemophilus influenzae 4.1 4.1 1 PMID:11305920 -1.1.1.405 d-ribulose haemophilus influenzae 3.6 3.6 1 PMID:11305920 -1.1.1.405 d-ribulose 5-phosphate haemophilus influenzae 22.0 22.0 1 PMID:11305920 -1.1.1.405 d-ribulose 5-phosphate streptococcus pneumoniae 0.5 0.5 1 PMID:19074383 -1.1.1.405 d-xylulose 5-phosphate haemophilus influenzae 3.6 3.6 1 PMID:11305920 -1.1.1.405 nadph haemophilus influenzae 22.0 7.41 3 PMID:11305920;PMID:15362865 -1.1.1.405 nadph staphylococcus aureus 6.08 3.435 2 PMID:15362865 -1.1.1.407 d-altritol agrobacterium fabrum 1.9 1.9 1 PMID:26472925 -1.1.1.408 4-hydroxy-l-threonine 4-phosphate cupriavidus necator 0.35 0.35 1 PMID:27402745 -1.1.1.408 4-hydroxy-l-threonine 4-phosphate salmonella enterica subsp. enterica serovar typhimurium 0.37 0.37 1 PMID:27402745 -1.1.1.408 4-phospho-d-threonate cupriavidus necator 3.4 3.4 1 PMID:27402745 -1.1.1.408 4-phospho-d-threonate salmonella enterica subsp. enterica serovar typhimurium 8.9 8.9 1 PMID:27402745 -1.1.1.41 d-isocitrate azotobacter vinelandii 73.0 73.0 1 PMID:15817777 -1.1.1.41 d-isocitrate colwellia maris 57.5 57.5 1 PMID:15817777 -1.1.1.41 d-isocitrate homo sapiens 30.0 30.0 1 PMID:16737955 -1.1.1.41 dl-isocitrate leishmania mexicana 78.98 78.98 1 PMID:32980452 -1.1.1.41 dl-isocitrate streptococcus mutans 124.0 124.0 1 PMID:23484056 -1.1.1.41 homoisocitrate pyrococcus horikoshii 13.7 13.7 1 PMID:15845397 -1.1.1.41 isocitrate campylobacter concisus 85.0 85.0 1 PMID:30876971 -1.1.1.41 isocitrate homo sapiens 30.0 30.0 1 PMID:16737955 -1.1.1.41 isocitrate pyrococcus horikoshii 14.8 14.8 1 PMID:15845397 -1.1.1.41 nad+ acidithiobacillus thiooxidans 45.1 45.1 1 PMID:12204383 -1.1.1.41 nad+ campylobacter concisus 78.0 78.0 1 PMID:30876971 -1.1.1.41 nad+ campylobacter curvus 10.8 10.8 1 PMID:25775177 -1.1.1.41 nad+ campylobacter sp. 7.0 7.0 1 PMID:25775177 -1.1.1.41 nad+ congregibacter litoralis 84.7 60.7 2 PMID:25942017 -1.1.1.41 nad+ homo sapiens 30.0 30.0 1 PMID:16737955 -1.1.1.41 nad+ leishmania mexicana 84.39 84.39 1 PMID:32980452 -1.1.1.41 nad+ methylobacillus flagellatus 166.0 166.0 1 PMID:28423051 -1.1.1.41 nad+ micromonas commoda 22.5 22.5 1 PMID:25775177 -1.1.1.41 nad+ ostreococcus sp. 'lucimarinus' 60.6 60.6 1 PMID:25775177 -1.1.1.41 nad+ ostreococcus tauri 115.0 87.0 2 PMID:25724193 -1.1.1.41 nad+ phaeodactylum tricornutum 180.5 129.75 2 PMID:32824636 -1.1.1.41 nad+ pyrococcus furiosus 60.4 60.4 1 PMID:12209263 -1.1.1.41 nad+ pyrococcus horikoshii 21.8 21.8 1 PMID:15845397 -1.1.1.41 nad+ streptococcus mutans 56.0 56.0 1 PMID:23484056 -1.1.1.41 nad+ xylella fastidiosa 74.6 74.6 1 PMID:28220528 -1.1.1.41 nad+ zymomonas mobilis 112.0 100.0 2 PMID:22117777 -1.1.1.41 nadp+ acidithiobacillus thiooxidans 21.3 21.3 1 PMID:12204383 -1.1.1.41 nadp+ azotobacter vinelandii 92.6 92.6 1 PMID:15817777 -1.1.1.41 nadp+ campylobacter concisus 33.0 33.0 1 PMID:30876971 -1.1.1.41 nadp+ campylobacter curvus 2.0 2.0 1 PMID:25775177 -1.1.1.41 nadp+ campylobacter sp. 1.9 1.9 1 PMID:25775177 -1.1.1.41 nadp+ colwellia maris 61.3 61.3 1 PMID:15817777 -1.1.1.41 nadp+ micromonas commoda 1.4 1.4 1 PMID:25775177 -1.1.1.41 nadp+ ostreococcus sp. 'lucimarinus' 10.0 10.0 1 PMID:25775177 -1.1.1.41 nadp+ ostreococcus tauri 46.0 31.5 2 PMID:25724193 -1.1.1.41 nadp+ pyrococcus furiosus 93.0 93.0 1 PMID:12209263 -1.1.1.41 nadp+ xylella fastidiosa 6.1 6.1 1 PMID:28220528 -1.1.1.41 nadp+ zymomonas mobilis 25.0 19.5 2 PMID:22117777 -1.1.1.410 d-erythronate cupriavidus necator 19.0 11.0 2 PMID:27402745 -1.1.1.411 d-gluconate agrobacterium tumefaciens 22.4 22.4 1 PMID:32569553 -1.1.1.411 d-xylonate agrobacterium tumefaciens 15.2 15.2 1 PMID:32569553 -1.1.1.411 l-idonate agrobacterium tumefaciens 21.1 18.75 2 PMID:32569553 -1.1.1.411 l-threonate agrobacterium tumefaciens 20.0 12.1 2 PMID:32569553 -1.1.1.411 l-threonate cupriavidus necator 29.0 15.6 2 PMID:27402745 -1.1.1.411 l-threonate pectobacterium atrosepticum 54.0 29.35 2 PMID:27402745 -1.1.1.412 (2r,3s)-2-hexyl-3-hydroxydecanoic acid stenotrophomonas maltophilia 1.3 1.3 1 PMID:21958090 -1.1.1.412 (2r/2s)-2-hexyl-3-oxodecanoic acid stenotrophomonas maltophilia 0.97 0.97 1 PMID:21958090 -1.1.1.412 syn-2-decyl-3-hydroxytetradecanoic acid stenotrophomonas maltophilia 1.4 1.4 1 PMID:21958090 -1.1.1.412 syn-2-hexyl-3-hydroxydecanoic acid stenotrophomonas maltophilia 1.2 1.2 1 PMID:21958090 -1.1.1.412 syn-2-octyl-3-hydroxydodecanoic acid stenotrophomonas maltophilia 2.0 2.0 1 PMID:21958090 -1.1.1.414 d-tagaturonate phocaeicola vulgatus 90.0 90.0 1 PMID:24963813 -1.1.1.414 l-galactonate escherichia coli 0.51 0.51 1 PMID:24861318 -1.1.1.414 l-galactonate phocaeicola vulgatus 0.6 0.6 1 PMID:24963813 -1.1.1.414 l-gluconate phocaeicola vulgatus 0.2 0.2 1 PMID:24963813 -1.1.1.415 nad+ papaver somniferum 0.54 0.54 1 PMID:24708518 -1.1.1.415 nadp+ papaver somniferum 1.73 1.73 1 PMID:24708518 -1.1.1.415 narcotine hemiacetal papaver somniferum 1.69 1.14 2 PMID:24708518 -1.1.1.416 isopyridoxal arthrobacter sp. cr-7 10.0 10.0 1 PMID:3533936 -1.1.1.42 2-oxoglutarate homo sapiens 4.9 3.5 15 PMID:28330869;PMID:32729927 -1.1.1.42 d-isocitrate plasmodium falciparum 138.0 138.0 1 PMID:12694190 -1.1.1.42 dl-isocitrate haloferax volcanii 0.0023 0.0023 1 PMID:16284723 -1.1.1.42 dl-isocitrate leishmania mexicana 83.03 83.03 1 PMID:32980452 -1.1.1.42 dl-isocitrate microcystis aeruginosa 43.21 27.065 4 PMID:23264072 -1.1.1.42 dl-isocitrate mycobacterium tuberculosis 19.6 3.8 3 PMID:16194279 -1.1.1.42 isocitrate acinetobacter baumannii 50.4 41.9 2 PMID:33290880 -1.1.1.42 isocitrate arabidopsis thaliana 4.93 4.93 1 PMID:30625997 -1.1.1.42 isocitrate archaeoglobus fulgidus 255.0 255.0 1 PMID:17401542 -1.1.1.42 isocitrate colwellia maris 69.88 69.88 1 PMID:31619337 -1.1.1.42 isocitrate desulfotalea psychrophila 31.4 17.95 2 PMID:17632124 -1.1.1.42 isocitrate escherichia coli 106.4 79.1 2 PMID:17401542;PMID:27406240 -1.1.1.42 isocitrate homo sapiens 85.0 33.7 18 PMID:28330869;PMID:32457458;PMID:32729927 -1.1.1.42 isocitrate mus musculus 5.6 5.6 1 PMID:28852116 -1.1.1.42 isocitrate mycobacterium tuberculosis 33.0 33.0 1 PMID:23409873 -1.1.1.42 isocitrate pseudomonas psychrophila 136.85 136.85 1 PMID:31619337 -1.1.1.42 isocitrate psychromonas marina 102.98 102.98 1 PMID:28447265 -1.1.1.42 isocitrate sus scrofa 58.3 58.3 1 * -1.1.1.42 nad+ bifidobacterium longum subsp. infantis 11.7 11.7 1 PMID:26927087 -1.1.1.42 nad+ streptomyces lividans 2.11 1.74 2 PMID:19631711 -1.1.1.42 nad+ sus scrofa 0.76 0.76 1 PMID:16712772 -1.1.1.42 nad+ xylella fastidiosa 96.5 56.6 2 PMID:28220528 -1.1.1.42 nadp+ acinetobacter baumannii 60.1 44.95 2 PMID:33290880 -1.1.1.42 nadp+ arabidopsis thaliana 5.81 5.81 1 PMID:30625997 -1.1.1.42 nadp+ archaeoglobus fulgidus 219.0 219.0 1 PMID:17401542 -1.1.1.42 nadp+ bifidobacterium longum subsp. infantis 36.4 36.4 1 PMID:26927087 -1.1.1.42 nadp+ desulfotalea psychrophila 31.4 17.95 2 PMID:17632124 -1.1.1.42 nadp+ escherichia coli 88.1 88.1 1 PMID:17401542 -1.1.1.42 nadp+ haloferax volcanii 0.003 0.003 1 PMID:16284723 -1.1.1.42 nadp+ homo sapiens 23.5 23.5 1 PMID:32457458 -1.1.1.42 nadp+ leishmania mexicana 84.29 84.29 1 PMID:32980452 -1.1.1.42 nadp+ methanococcoides methylutens 55.5 55.5 1 PMID:31970482 -1.1.1.42 nadp+ methylobacillus flagellatus 56.0 56.0 1 PMID:28423051 -1.1.1.42 nadp+ microcystis aeruginosa 48.88 37.120000000000005 4 PMID:23264072 -1.1.1.42 nadp+ mus musculus 6.36 6.36 1 PMID:28852116 -1.1.1.42 nadp+ mycobacterium tuberculosis 37.4 33.0 3 PMID:16194279;PMID:23409873 -1.1.1.42 nadp+ plasmodium falciparum 138.0 138.0 1 PMID:12694190 -1.1.1.42 nadp+ streptomyces lividans 27.6 25.4 2 PMID:19631711 -1.1.1.42 nadp+ sus scrofa 32.2 32.2 1 PMID:16712772 -1.1.1.42 nadp+ yarrowia lipolytica 72.0 72.0 1 PMID:23846800 -1.1.1.422 (+)-(1s,2s)-pseudoephedrine arthrobacter sp. ts-15 3.77 3.77 1 PMID:31900306 -1.1.1.422 (s,r)-(+)-ephedrine arthrobacter sp. ts-15 1.45 1.45 1 PMID:31900306 -1.1.1.422 (s,s)-(+)-pseudoephedrine arthrobacter sp. ts-15 3.77 3.77 1 PMID:31900306 -1.1.1.422 1,2-indandione arthrobacter sp. ts-15 6.55 6.55 1 * -1.1.1.422 1,2-indanedione arthrobacter sp. 6.55 6.55 1 * -1.1.1.422 1,2-naphthoquinone arthrobacter sp. 12.76 12.76 1 * -1.1.1.422 1,2-naphthoquinone arthrobacter sp. ts-15 12.76 12.76 1 * -1.1.1.422 1-phenyl-1,2-propanedione arthrobacter sp. 34.24 34.24 1 * -1.1.1.422 1-phenyl-1,2-propanedione arthrobacter sp. ts-15 34.24 34.24 1 * -1.1.1.422 1-phenylpropan-1,2-dione arthrobacter sp. ts-15 34.24 34.24 1 * -1.1.1.422 2-aminoacetophenone arthrobacter sp. 5.44 5.44 1 * -1.1.1.422 2-aminoacetophenone arthrobacter sp. ts-15 5.44 5.44 1 * -1.1.1.422 2-bromo-1-(3-chlorophenyl)-1-propanone arthrobacter sp. 9.52 9.52 1 * -1.1.1.422 2-bromo-1-(3-chlorophenyl)-1-propanone arthrobacter sp. ts-15 9.52 9.52 1 * -1.1.1.422 2-chloro-1-phenyl-1-propane arthrobacter sp. ts-15 3.8 3.8 1 * -1.1.1.422 2-chloro-1-phenyl-1-propanone arthrobacter sp. 3.8 3.8 1 * -1.1.1.422 4-chlorobenzil arthrobacter sp. 3.75 3.75 1 * -1.1.1.422 4-chlorobenzil arthrobacter sp. ts-15 3.75 3.75 1 * -1.1.1.422 ethyl 2-chlorobenzoylacetate arthrobacter sp. 9.89 9.89 1 * -1.1.1.422 ethyl 2-chlorobenzoylacetate arthrobacter sp. ts-15 9.89 9.89 1 * -1.1.1.422 isatin arthrobacter sp. 43.95 43.95 1 * -1.1.1.422 isatin arthrobacter sp. ts-15 43.95 43.95 1 * -1.1.1.422 methyl benzoylformate arthrobacter sp. 109.18 109.18 1 * -1.1.1.422 methyl benzoylformate arthrobacter sp. ts-15 109.18 109.18 1 * -1.1.1.422 nad+ arthrobacter sp. ts-15 9.22 9.22 1 PMID:31900306 -1.1.1.423 1,2-indandione arthrobacter sp. ts-15 31.11 31.11 1 * -1.1.1.423 1,2-indanedione arthrobacter sp. ts-15 31.11 31.11 1 * -1.1.1.423 1,2-naphthoquinone arthrobacter sp. ts-15 7.94 7.94 1 * -1.1.1.423 1-phenyl-1,2-propanedione arthrobacter sp. ts-15 30.43 30.43 1 * -1.1.1.423 1-phenyl-1,3-butanedione arthrobacter sp. ts-15 15.37 15.37 1 * -1.1.1.423 1-phenyl-1-propanone arthrobacter sp. ts-15 0.77 0.77 1 * -1.1.1.423 2-aminoacetophenone arthrobacter sp. ts-15 27.13 27.125 2 * -1.1.1.423 2-bromo-1-(3-chlorophenyl)-1-propanone arthrobacter sp. ts-15 2.54 2.54 1 * -1.1.1.423 2-chloro-1-phenyl-1-propane arthrobacter sp. ts-15 7.31 7.31 1 * -1.1.1.423 2-chloro-1-phenyl-1-propanone arthrobacter sp. ts-15 7.31 7.31 1 * -1.1.1.423 4-chlorobenzil arthrobacter sp. ts-15 3.48 3.48 1 * -1.1.1.423 ethyl 2-chlorobenzoylacetate arthrobacter sp. ts-15 37.38 37.38 1 * -1.1.1.423 isatin arthrobacter sp. ts-15 4.36 4.36 1 * -1.1.1.423 methyl benzoylformate arthrobacter sp. ts-15 40.05 40.05 1 * -1.1.1.423 nadh arthrobacter sp. ts-15 15.74 15.74 1 * -1.1.1.423 phenylglyoxal arthrobacter sp. ts-15 9.49 9.49 1 * -1.1.1.424 d-glucose haloarcula marismortui 273.0 273.0 1 PMID:15342590 -1.1.1.424 d-ribose haloarcula marismortui 360.0 360.0 1 PMID:15342590 -1.1.1.424 d-xylose haloarcula marismortui 356.0 356.0 1 PMID:15342590 -1.1.1.425 levoglucosan arthrobacter sp. i-552 333.0 333.0 1 PMID:7765713 -1.1.1.427 2,3-pentanedione saccharomyces cerevisiae 5.9 5.9 1 PMID:17030441 -1.1.1.427 d-arabinose candida albicans 68.2 68.2 1 PMID:8841374 -1.1.1.427 d-arabinose saccharolobus solfataricus 23.8 23.8 1 PMID:16849334 -1.1.1.427 d-ribose saccharolobus solfataricus 17.7 17.7 1 PMID:16849334 -1.1.1.427 diacetyl saccharomyces cerevisiae 6.9 6.9 1 PMID:17030441 -1.1.1.427 l-fucose candida albicans 69.5 69.5 1 PMID:8841374 -1.1.1.427 l-fucose saccharolobus solfataricus 26.8 26.8 1 PMID:16849334 -1.1.1.427 l-galactose candida albicans 53.2 53.2 1 PMID:8841374 -1.1.1.427 l-galactose saccharolobus solfataricus 17.7 17.7 1 PMID:16849334 -1.1.1.427 l-xylose candida albicans 63.4 63.4 1 PMID:8841374 -1.1.1.427 methylglyoxal saccharomyces cerevisiae 4.4 4.4 1 PMID:17030441 -1.1.1.427 nadph saccharomyces cerevisiae 3.7 3.7 1 PMID:17030441 -1.1.1.430 2-deoxy-d-galactose sungouiella intermedia 3.5 3.5 1 PMID:14690376 -1.1.1.430 9,10-phenanthrenequinone yamadazyma tenuis 12.0 12.0 1 PMID:19368528 -1.1.1.430 butanal sungouiella intermedia 5.4 5.4 1 PMID:14690376 -1.1.1.430 d-erythrose sungouiella intermedia 27.5 27.5 1 PMID:14690376 -1.1.1.430 d-fucose sungouiella intermedia 10.2 10.2 1 PMID:14690376 -1.1.1.430 d-galactose sungouiella intermedia 9.4 9.4 1 PMID:14690376 -1.1.1.430 d-glucose sungouiella intermedia 5.6 5.6 1 PMID:14690376 -1.1.1.430 d-ribose sungouiella intermedia 4.9 4.9 1 PMID:14690376 -1.1.1.430 d-xylose scheffersomyces stipitis 27.5 21.45 2 PMID:18028553 -1.1.1.430 d-xylose sungouiella intermedia 16.9 16.9 1 PMID:14690376 -1.1.1.430 d-xylose yamadazyma tenuis 14.2 11.42 3 PMID:11513616;PMID:19368528 -1.1.1.430 dl-glyceraldehyde sungouiella intermedia 14.1 14.1 1 PMID:14690376 -1.1.1.430 l-arabinose sungouiella intermedia 13.5 13.5 1 PMID:14690376 -1.1.1.430 l-lyxose sungouiella intermedia 6.6 6.6 1 PMID:14690376 -1.1.1.430 nad+ yamadazyma tenuis 0.92 0.92 1 PMID:11513616 -1.1.1.430 nadh scheffersomyces stipitis 15.4 15.4 1 PMID:18028553 -1.1.1.430 nadh yamadazyma tenuis 14.2 12.809999999999999 2 PMID:11513616 -1.1.1.430 nadph scheffersomyces stipitis 27.5 27.5 1 PMID:18028553 -1.1.1.430 pentanal sungouiella intermedia 5.9 5.9 1 PMID:14690376 -1.1.1.430 propionaldehyde sungouiella intermedia 4.6 4.6 1 PMID:14690376 -1.1.1.430 xylitol yamadazyma tenuis 0.92 0.92 1 PMID:11513616 -1.1.1.431 2-deoxy-d-galactose sungouiella intermedia 8.4 8.4 1 PMID:14690376 -1.1.1.431 2-deoxy-d-glucose sungouiella intermedia 6.8 6.8 1 PMID:14690376 -1.1.1.431 2-deoxy-d-ribose sungouiella intermedia 1.4 1.4 1 PMID:14690376 -1.1.1.431 5,6-dideoxy-5,6-difluoro-d-glucofuranose saitozyma flava 19.0 19.0 1 PMID:10548539 -1.1.1.431 5,6-dideoxy-5,6-difluoro-d-glucofuranose sungouiella intermedia 22.0 22.0 1 PMID:10548539 -1.1.1.431 5,6-dideoxy-5-fluoro-d-glucofuranose saitozyma flava 14.0 14.0 1 PMID:10548539 -1.1.1.431 5,6-dideoxy-5-fluoro-d-glucofuranose sungouiella intermedia 21.0 21.0 1 PMID:10548539 -1.1.1.431 5,6-dideoxy-6-fluoro-d-xylo-hexofuranose saitozyma flava 14.0 14.0 1 PMID:10548539 -1.1.1.431 5,6-dideoxy-6-fluoro-d-xylo-hexofuranose sungouiella intermedia 34.0 34.0 1 PMID:10548539 -1.1.1.431 5,6-dideoxy-d-xylo-hexofuranose saitozyma flava 15.0 15.0 1 PMID:10548539 -1.1.1.431 5,6-dideoxy-d-xylo-hexofuranose sungouiella intermedia 27.0 27.0 1 PMID:10548539 -1.1.1.431 5-azido-5-deoxy-d-xylofuranose saitozyma flava 11.2 11.2 1 PMID:10548539 -1.1.1.431 5-deoxy-d-xylofuranose saitozyma flava 12.5 12.5 1 PMID:10548539 -1.1.1.431 5-deoxy-d-xylofuranose sungouiella intermedia 18.1 18.1 1 PMID:10548539 -1.1.1.431 5-fluoro-5-deoxy-d-xylofuranose saitozyma flava 15.6 15.6 1 PMID:10548539 -1.1.1.431 5-fluoro-5-deoxy-d-xylofuranose sungouiella intermedia 20.0 20.0 1 PMID:10548539 -1.1.1.431 6-azido-5,6-dideoxy-5-fluoro-d-glucofuranose saitozyma flava 14.0 14.0 1 PMID:10548539 -1.1.1.431 6-azido-5,6-dideoxy-5-fluoro-d-glucofuranose sungouiella intermedia 19.0 19.0 1 PMID:10548539 -1.1.1.431 butanal sungouiella intermedia 21.2 21.2 1 PMID:14690376 -1.1.1.431 cyclohexanecarboxaldehyde saitozyma flava 6.3 6.3 1 PMID:10548539 -1.1.1.431 cyclohexanecarboxaldehyde sungouiella intermedia 13.1 13.1 1 PMID:10548539 -1.1.1.431 d-erythrose debaryomyces nepalensis 165.0 165.0 1 PMID:30269423 -1.1.1.431 d-erythrose sungouiella intermedia 24.3 24.3 1 PMID:14690376 -1.1.1.431 d-fructose saccharomyces cerevisiae 530.0 466.0 3 PMID:30686349 -1.1.1.431 d-fucose sungouiella intermedia 20.7 20.7 1 PMID:14690376 -1.1.1.431 d-galactose saccharomyces cerevisiae 410.0 360.0 3 PMID:30686349 -1.1.1.431 d-galactose saitozyma flava 5.9 5.9 1 PMID:10548539 -1.1.1.431 d-galactose sungouiella intermedia 15.2 12.3 2 PMID:10548539;PMID:14690376 -1.1.1.431 d-glucose saccharomyces cerevisiae 3190.0 1920.0 3 PMID:30686349 -1.1.1.431 d-glucose sungouiella intermedia 8.2 8.2 1 PMID:14690376 -1.1.1.431 d-ribose sungouiella intermedia 12.2 12.2 1 PMID:14690376 -1.1.1.431 d-xylose aspergillus niger 9.65 9.65 1 PMID:33842213 -1.1.1.431 d-xylose neurospora crassa 4638.0 4638.0 1 PMID:8620033 -1.1.1.431 d-xylose rhizomucor pusillus 21.3 21.3 1 PMID:25041710 -1.1.1.431 d-xylose saccharomyces cerevisiae 343.0 192.0 4 PMID:11481678;PMID:30686349 -1.1.1.431 d-xylose saitozyma flava 8.8 8.8 1 PMID:10548539 -1.1.1.431 d-xylose scheffersomyces stipitis 8.37 5.515000000000001 4 PMID:30487522 -1.1.1.431 d-xylose sungouiella intermedia 23.5 14.6 3 PMID:10548539;PMID:10681056;PMID:14690376 -1.1.1.431 d-xylose thermomyces lanuginosus 194.3 194.3 1 PMID:30831517 -1.1.1.431 dl-glyceraldehyde sungouiella intermedia 24.3 24.3 1 PMID:14690376 -1.1.1.431 l-arabinose aspergillus niger 15.61 15.61 1 PMID:33842213 -1.1.1.431 l-arabinose saccharomyces cerevisiae 1030.0 1000.0 3 PMID:30686349 -1.1.1.431 l-arabinose sungouiella intermedia 24.5 24.5 1 PMID:14690376 -1.1.1.431 l-lyxose sungouiella intermedia 18.4 18.4 1 PMID:14690376 -1.1.1.431 nadh scheffersomyces stipitis 2.68 2.535 2 PMID:30487522 -1.1.1.431 nadph saccharomyces cerevisiae 0.17 0.14 3 PMID:30686349 -1.1.1.431 nadph scheffersomyces stipitis 7.65 7.640000000000001 2 PMID:30487522 -1.1.1.431 nadph sungouiella intermedia 14.6 14.6 1 PMID:10681056 -1.1.1.431 oenanthaldehyde saitozyma flava 9.2 9.2 1 PMID:10548539 -1.1.1.431 oenanthaldehyde sungouiella intermedia 22.0 22.0 1 PMID:10548539 -1.1.1.431 pentanal sungouiella intermedia 20.7 20.7 1 PMID:14690376 -1.1.1.431 propionaldehyde sungouiella intermedia 6.9 6.9 1 PMID:14690376 -1.1.1.431 xylitol sungouiella intermedia 0.6 0.6 1 PMID:14690376 -1.1.1.433 2-sulfoacetaldehyde bifidobacterium catenulatum subsp. kashiwanohense 22.83 22.83 2 PMID:31123167 -1.1.1.433 isethionate bifidobacterium catenulatum subsp. kashiwanohense 0.97 0.97 2 PMID:31123167 -1.1.1.433 nad+ bifidobacterium catenulatum subsp. kashiwanohense 1.3 1.3 2 PMID:31123167 -1.1.1.433 nadh bifidobacterium catenulatum subsp. kashiwanohense 18.67 18.67 2 PMID:31123167 -1.1.1.433 nadp+ bifidobacterium catenulatum subsp. kashiwanohense 0.8 0.8 1 PMID:31123167 -1.1.1.433 nadph bifidobacterium catenulatum subsp. kashiwanohense 18.99 18.99 1 PMID:31123167 -1.1.1.434 2-dehydro-3-deoxy-l-fuconate xanthomonas campestris pv. campestris 9.8 7.3 3 PMID:17144652 -1.1.1.435 4-deoxy-l-fucose burkholderia multivorans 26.0 26.0 1 PMID:23214453 -1.1.1.435 beta-l-fucose burkholderia multivorans 10.0 10.0 1 PMID:23214453 -1.1.1.435 d-arabinose burkholderia multivorans 21.0 21.0 1 PMID:23214453 -1.1.1.435 l-galactose burkholderia multivorans 11.0 11.0 1 PMID:23214453 -1.1.1.435 nad+ burkholderia multivorans 5.0 5.0 1 PMID:23214453 -1.1.1.435 nadp+ burkholderia multivorans 11.0 11.0 1 PMID:23214453 -1.1.1.44 6,7-dideoxy-7-phosphono-d-glucoheptonate ovis aries 0.53 0.53 1 PMID:12628648 -1.1.1.44 6,7-dideoxy-7-phosphono-d-glucoheptonate trypanosoma brucei 1.4 1.4 1 PMID:12628648 -1.1.1.44 6-phospho-d-gluconate geobacillus stearothermophilus 22.1 22.1 1 * -1.1.1.44 6-phospho-d-gluconate homo sapiens 73.0 22.2 3 PMID:24018234;PMID:30098336 -1.1.1.44 6-phospho-d-gluconate plasmodium falciparum 7.1 7.1 2 PMID:30098336 -1.1.1.44 6-phospho-d-gluconate synechocystis sp. 64.5 64.5 1 PMID:30107441 -1.1.1.44 6-phospho-d-gluconate thermotoga maritima 325.0 325.0 1 PMID:19497097 -1.1.1.44 6-phosphogluconate homo sapiens 0.217 0.217 1 PMID:1128263 -1.1.1.44 6-phosphono-d-gluconate ovis aries 9.0 9.0 1 PMID:12628648 -1.1.1.44 6-phosphono-d-gluconate trypanosoma brucei 31.8 31.8 1 PMID:12628648 -1.1.1.44 6-phosphono-d-gluconate trypanosoma cruzi 98.0 98.0 1 PMID:14698432 -1.1.1.44 nad+ neomoorella thermoacetica 12.6 12.6 1 PMID:27587230 -1.1.1.44 nad+ synechocystis sp. 4.89 4.89 1 PMID:30107441 -1.1.1.44 nad+ thermotoga maritima 23.3 23.3 1 PMID:27805055 -1.1.1.44 nadp+ geobacillus stearothermophilus 22.1 22.1 1 * -1.1.1.44 nadp+ homo sapiens 71.0 21.4 3 PMID:24018234;PMID:30098336 -1.1.1.44 nadp+ limnospira platensis 16.6 16.6 1 PMID:30107441 -1.1.1.44 nadp+ neomoorella thermoacetica 8.73 8.73 1 PMID:27587230 -1.1.1.44 nadp+ plasmodium falciparum 7.6 7.6 2 PMID:30098336 -1.1.1.44 nadp+ synechocystis sp. 69.9 69.9 1 PMID:30107441 -1.1.1.44 nadp+ thermotoga maritima 325.0 171.3 2 PMID:19497097;PMID:27805055 -1.1.1.44 nadp+ trypanosoma cruzi 98.0 98.0 1 PMID:14698432 -1.1.1.441 ditrans,polycis-polyprenol cricetulus griseus 0.17 0.17 1 PMID:39395802 -1.1.1.441 ditrans,polycis-polyprenol homo sapiens 0.44 0.44 1 PMID:38821050 -1.1.1.441 dolichal cricetulus griseus 1.01 1.01 1 PMID:39395802 -1.1.1.441 dolichal homo sapiens 1.0 1.0 1 PMID:38821050 -1.1.1.441 nad+ cricetulus griseus 0.22 0.22 1 PMID:39395802 -1.1.1.441 nad+ homo sapiens 0.16 0.16 1 PMID:38821050 -1.1.1.441 nadh cricetulus griseus 0.68 0.68 1 PMID:39395802 -1.1.1.441 nadh homo sapiens 0.62 0.62 1 PMID:38821050 -1.1.1.441 nadp+ cricetulus griseus 0.22 0.22 1 PMID:39395802 -1.1.1.441 nadp+ homo sapiens 0.18 0.18 1 PMID:38821050 -1.1.1.441 nadph cricetulus griseus 0.58 0.58 1 PMID:39395802 -1.1.1.441 nadph homo sapiens 0.65 0.65 1 PMID:38821050 -1.1.1.45 dl-3-hydroxybutanoate drosophila melanogaster 0.733 0.733 1 PMID:37912 -1.1.1.45 l-gulonate drosophila melanogaster 7.4 7.4 1 PMID:37912 -1.1.1.47 1-(3-phenylpropyl)-1,4-dihydropyridine-3-carboxamide saccharolobus solfataricus 0.00096 0.00096 1 * -1.1.1.47 1-benzyl-3-carbamoylpyridin-1-ium chloride saccharolobus solfataricus 0.0016 0.0016 1 * -1.1.1.47 1-phenethyl-1,4-dihydropyridine-3-carboxamide saccharolobus solfataricus 0.00396 0.00396 1 * -1.1.1.47 beta-d-galactose saccharolobus solfataricus 61.0 49.0 2 PMID:16556607 -1.1.1.47 beta-d-glucose priestia megaterium 802.0 392.5 10 PMID:12743762;PMID:1629157;PMID:2075979 -1.1.1.47 beta-d-glucose saccharolobus solfataricus 75.0 58.115 4 PMID:16556607;PMID:21265750 -1.1.1.47 d-glucose bacillus amyloliquefaciens 70.0 70.0 1 PMID:26538191 -1.1.1.47 d-glucose bacillus sp. (in: firmicutes) 87.84 87.84 1 PMID:28587256 -1.1.1.47 d-glucose bos taurus 45.9 43.45 2 PMID:7553351 -1.1.1.47 d-glucose oncorhynchus mykiss 14.7 12.899999999999999 2 PMID:7553351 -1.1.1.47 d-glucose priestia megaterium 395.0 190.0 10 PMID:15933031;PMID:2513190 -1.1.1.47 d-glucose saccharolobus solfataricus 68.23 43.785000000000004 2 * -1.1.1.47 d-glucose 6-phosphate bos taurus 1.6 1.55 2 PMID:7553351 -1.1.1.47 d-glucose 6-phosphate oncorhynchus mykiss 14.2 12.7 3 PMID:7553351 -1.1.1.47 d-xylose saccharolobus solfataricus 61.0 52.5 2 PMID:16556607 -1.1.1.47 nad+ bacillus sp. (in: firmicutes) 84.52 84.52 1 PMID:28587256 -1.1.1.47 nad+ bacillus subtilis 521000.0 521000.0 1 PMID:27502455 -1.1.1.47 nad+ lysinibacillus sphaericus 115.0 115.0 3 PMID:20805024;PMID:24315638 -1.1.1.47 nad+ priestia megaterium 390.0 390.0 1 PMID:2075979 -1.1.1.47 nad+ saccharolobus solfataricus 105.4 65.895 6 PMID:12824170 -1.1.1.47 nadp+ bacillus sp. (in: firmicutes) 73.96 73.96 1 PMID:28587256 -1.1.1.47 nadp+ lysinibacillus sphaericus 93.0 93.0 2 PMID:20805024;PMID:24315638 -1.1.1.47 nadp+ priestia megaterium 260.0 260.0 1 PMID:2075979 -1.1.1.47 nadp+ saccharolobus solfataricus 47.7 37.4 5 PMID:12824170 -1.1.1.48 d-galactose pseudomonas fluorescens 1180.0 1180.0 1 PMID:4153311 -1.1.1.48 d-galactose roseateles saccharophilus 358.0 358.0 1 PMID:4149284 -1.1.1.49 2-deoxy-d-glucose 6-phosphate thermotoga maritima 1800.0 1800.0 1 PMID:12435510 -1.1.1.49 2-deoxyglucose 6-phosphate homo sapiens 43.0 43.0 1 PMID:11311853 -1.1.1.49 d-galactose 6-phosphate homo sapiens 157.0 157.0 1 PMID:11311853 -1.1.1.49 d-glucose 6-phosphate aspergillus aculeatus 83.0 83.0 1 PMID:16202239 -1.1.1.49 d-glucose 6-phosphate homo sapiens 571.0 275.0 7 PMID:11311853;PMID:16088936;PMID:16934959;PMID:17959407;PMID:19284595;PMID:27053284 -1.1.1.49 d-glucose 6-phosphate leishmania mexicana 22.2 22.2 1 PMID:19231202 -1.1.1.49 d-glucose 6-phosphate taenia crassiceps 34.0 34.0 1 PMID:18297308 -1.1.1.49 d-glucose 6-phosphate thermotoga maritima 3500.0 3500.0 1 PMID:12435510 -1.1.1.49 d-glucose 6-phosphate trypanosoma brucei 16.4 16.4 1 PMID:19231202 -1.1.1.49 d-glucose 6-phosphate trypanosoma cruzi 62.0 59.55 2 PMID:20570159;PMID:26999093 -1.1.1.49 d-glucose 6-phosphate zymomonas mobilis subsp. mobilis 305.0 305.0 1 PMID:29480380 -1.1.1.49 deamino-nadp+ homo sapiens 98.0 98.0 1 PMID:11311853 -1.1.1.49 nad+ escherichia coli 288.0 288.0 2 PMID:22519976;PMID:27010804 -1.1.1.49 nad+ pseudomonas fluorescens 1380.0 1380.0 1 PMID:1257 -1.1.1.49 nad+ thermotoga maritima 1100.0 1100.0 1 PMID:12435510 -1.1.1.49 nadp+ escherichia coli 174.0 174.0 2 PMID:22519976;PMID:27010804 -1.1.1.49 nadp+ homo sapiens 251.0 249.0 2 PMID:17959407;PMID:27053284 -1.1.1.49 nadp+ pseudomonas fluorescens 1120.0 1120.0 1 PMID:1257 -1.1.1.49 nadp+ taenia crassiceps 34.0 34.0 1 PMID:18297308 -1.1.1.49 nadp+ thermotoga maritima 3500.0 3500.0 1 PMID:12435510 -1.1.1.49 nadp+ trypanosoma cruzi 52.0 52.0 1 PMID:26999093 -1.1.1.49 nadp+ zymomonas mobilis subsp. mobilis 305.0 305.0 1 PMID:29480380 -1.1.1.49 thio-nad+ thermotoga maritima 2100.0 2100.0 1 PMID:12435510 -1.1.1.49 thio-nadp+ thermotoga maritima 8000.0 8000.0 1 PMID:12435510 -1.1.1.50 (2z)-2-(5-hydroxy-4,6-dimethyl-2-oxo-1,2-dihydro-3h-indol-3-ylidene)-n,n-di(prop-2-en-1-yl)hydrazinecarbothioamide homo sapiens 0.507 0.203 5 PMID:12810547;PMID:9415401 -1.1.1.50 (3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oic acid pseudomonas sp. 82.0 82.0 1 * -1.1.1.50 (5beta,20r)-20-hydroxypregnan-3-one rattus norvegicus 0.115 0.115 1 PMID:17475203 -1.1.1.50 1-acenaphthenol homo sapiens 0.59 0.45499999999999996 4 PMID:15026176 -1.1.1.50 1-indanol homo sapiens 0.21 0.1605 4 PMID:15026176 -1.1.1.50 2-decalol comamonas testosteroni 2.2 2.2 1 PMID:28137513 -1.1.1.50 3alpha-adiol homo sapiens 0.183 0.183 1 PMID:9188497 -1.1.1.50 3alpha-adiol rattus norvegicus 0.0833 0.0833 1 PMID:9188497 -1.1.1.50 3alpha-androstanediol homo sapiens 0.008 0.008 1 PMID:17059222 -1.1.1.50 3alpha-hydroxytibolone homo sapiens 0.012 0.006008 2 PMID:15383625 -1.1.1.50 3beta-hydroxytibolone homo sapiens 0.016 0.0022500000000000003 4 PMID:15383625 -1.1.1.50 4-nitrobenzaldehyde homo sapiens 1.08 1.08 1 PMID:9415401 -1.1.1.50 4-pregnen-3alpha,20beta-diol homo sapiens 0.0735 0.02425 4 PMID:14672942 -1.1.1.50 5alpha-androstane-3,17-dione rattus norvegicus 0.42 0.42 1 PMID:17848571 -1.1.1.50 5alpha-dihydroprogesterone homo sapiens 0.04 0.006 4 PMID:11995921;PMID:12416991;PMID:14982413 -1.1.1.50 5alpha-dihydrotestosterone homo sapiens 0.114 0.0398 7 PMID:12604225;PMID:12810547;PMID:17059222;PMID:24434280;PMID:9415401 -1.1.1.50 5alpha-dihydrotestosterone rattus norvegicus 1.0 1.0 1 PMID:12604225 -1.1.1.50 5beta-androstane-3,17-dione rattus norvegicus 0.047 0.047 1 PMID:17475203 -1.1.1.50 5beta-dihydroprogesterone homo sapiens 0.05 0.018 3 PMID:11995921;PMID:12416991 -1.1.1.50 5beta-pregnane-3,20-dione rattus norvegicus 0.105 0.105 1 PMID:17475203 -1.1.1.50 6-tert-butyl-2,3-epoxy-4-hydroxy-5-cyclohexen-1-one rattus norvegicus 0.1 0.1 1 PMID:17475203 -1.1.1.50 9,10-phenanthrenequinone homo sapiens 18.9 18.9 1 PMID:9415401 -1.1.1.50 9,10-phenanthrenequinone rattus norvegicus 0.183 0.183 1 PMID:17475203 -1.1.1.50 allopregnanolone homo sapiens 0.00017 0.00017 1 PMID:12416991 -1.1.1.50 androstanedione homo sapiens 1.9 1.9 1 PMID:9415401 -1.1.1.50 androstenol comamonas testosteroni 230.0 230.0 1 PMID:28137513 -1.1.1.50 androsterone comamonas testosteroni 500.0 409.0 2 PMID:15572373;PMID:28137513 -1.1.1.50 androsterone homo sapiens 0.133 0.007415 4 PMID:15026176;PMID:9188497;PMID:9415401 -1.1.1.50 androsterone pseudomonas sp. 134.0 134.0 1 * -1.1.1.50 androsterone rattus norvegicus 2.6 0.82 3 PMID:17848571;PMID:6586631;PMID:9188497 -1.1.1.50 benzenedihydrodiol homo sapiens 0.05 0.025 4 PMID:15026176 -1.1.1.50 chenodeoxycholic acid pseudomonas sp. 76.0 76.0 1 * -1.1.1.50 cholate pseudomonas sp. b-0831 23.0 23.0 1 PMID:29912635 -1.1.1.50 cholic acid pseudomonas sp. 75.0 55.0 2 * -1.1.1.50 cyclohexanol comamonas testosteroni 2.5 2.5 1 PMID:28137513 -1.1.1.50 dehydrocholate pseudomonas sp. b-0831 48.0 48.0 1 PMID:29912635 -1.1.1.50 dehydrolithocholic acid rattus norvegicus 0.022 0.022 1 PMID:17475203 -1.1.1.50 diacetyl rattus norvegicus 0.167 0.167 1 PMID:17475203 -1.1.1.50 fusidic acid pseudomonas sp. 25.0 24.0 2 * -1.1.1.50 glycocholic acid pseudomonas sp. 77.0 77.0 1 * -1.1.1.50 isatin rattus norvegicus 0.283 0.283 1 PMID:17475203 -1.1.1.50 lithocholic acid pseudomonas sp. 72.0 72.0 1 * -1.1.1.50 nadh comamonas testosteroni 63.0 63.0 1 PMID:19520191 -1.1.1.50 nadp+ homo sapiens 0.00017 0.00017 1 PMID:12416991 -1.1.1.50 nadph homo sapiens 0.003 0.003 1 PMID:12416991 -1.1.1.50 oxidized 8-acetyl-2,3,5,6-tetrahydro-1h,4h-11-oxa-3a-azabenzo[de]anthracen-10-one homo sapiens 0.14 0.14 1 PMID:14982413 -1.1.1.50 pregn-4-en-3,20-dione homo sapiens 0.0035 0.0035 1 PMID:24434280 -1.1.1.50 stanolone homo sapiens 0.0167 0.0167 1 PMID:9188497 -1.1.1.50 taurocholic acid pseudomonas sp. 74.0 74.0 1 * -1.1.1.50 testosterone homo sapiens 0.0757 0.0757 1 PMID:9415401 -1.1.1.51 (r)-1,2,3,4-tetrahydro-1-naphthol mesocricetus auratus 0.022 0.022 1 PMID:26002966 -1.1.1.51 (s)-1,2,3,4-tetrahydro-1-naphthol mesocricetus auratus 0.025 0.025 1 PMID:26002966 -1.1.1.51 (s)-1-indanol mesocricetus auratus 0.028 0.028 1 PMID:26002966 -1.1.1.51 1-acenaphthenol mesocricetus auratus 0.022 0.022 1 PMID:26002966 -1.1.1.51 17beta-estradiol mesocricetus auratus 0.022 0.022 1 PMID:26002966 -1.1.1.51 2-cyclohexen-1-ol mesocricetus auratus 0.04 0.04 1 PMID:26002966 -1.1.1.51 20alpha-dihydroprogesterone homo sapiens 0.78 0.78 1 PMID:11940569 -1.1.1.51 3beta-hydroxyprogesterone mesocricetus auratus 0.056 0.056 1 PMID:26002966 -1.1.1.51 4-androstene-3alpha,17beta-diol mesocricetus auratus 0.043 0.043 1 PMID:26002966 -1.1.1.51 5-androstene-3beta,17beta-diol mesocricetus auratus 0.043 0.043 1 PMID:26002966 -1.1.1.51 5alpha-androstan-3beta-ol-17-one mesocricetus auratus 0.027 0.027 1 PMID:26002966 -1.1.1.51 5alpha-dihydrotestosterone mesocricetus auratus 0.057 0.057 1 PMID:26002966 -1.1.1.51 5alpha-pregnan-3beta-ol-20-one mesocricetus auratus 0.013 0.013 1 PMID:26002966 -1.1.1.51 5beta-androstan-3beta-ol-17-one mesocricetus auratus 0.022 0.022 1 PMID:26002966 -1.1.1.51 5beta-androstane-3alpha,17beta-diol mesocricetus auratus 0.012 0.012 1 PMID:26002966 -1.1.1.51 5beta-androstane-3beta,17beta-diol mesocricetus auratus 0.036 0.036 1 PMID:26002966 -1.1.1.51 5beta-dihydrotestosterone mesocricetus auratus 0.032 0.032 1 PMID:26002966 -1.1.1.51 5beta-pregnan-3beta,21-diol-20-one mesocricetus auratus 0.0043 0.0043 1 PMID:26002966 -1.1.1.51 5beta-pregnan-3beta-ol-20-one mesocricetus auratus 0.0028 0.0028 1 PMID:26002966 -1.1.1.51 alpha-3-hydroxyhexobarbital mesocricetus auratus 0.018 0.018 1 PMID:26002966 -1.1.1.51 beta-3-hydroxyhexobarbital mesocricetus auratus 0.025 0.025 1 PMID:26002966 -1.1.1.51 beta-ionol mesocricetus auratus 0.022 0.022 1 PMID:26002966 -1.1.1.51 cis-benzene dihydrodiol mesocricetus auratus 0.025 0.025 1 PMID:26002966 -1.1.1.51 cyclohexanol mesocricetus auratus 0.009 0.009 1 PMID:26002966 -1.1.1.51 dehydroepiandrosterone mesocricetus auratus 0.01 0.01 1 PMID:26002966 -1.1.1.51 dihydrotestosterone homo sapiens 2.4 2.4 1 PMID:11940569 -1.1.1.51 estradiol homo sapiens 3.9 3.9 1 PMID:11940569 -1.1.1.51 farnesol mesocricetus auratus 0.018 0.018 1 PMID:26002966 -1.1.1.51 geraniol mesocricetus auratus 0.023 0.023 1 PMID:26002966 -1.1.1.51 geranylgeraniol mesocricetus auratus 0.008 0.008 1 PMID:26002966 -1.1.1.51 nad+ homo sapiens 4.7 3.8 2 PMID:11940569 -1.1.1.51 nad+ mesocricetus auratus 0.11 0.11 1 PMID:26002966 -1.1.1.51 nadh homo sapiens 0.33 0.30000000000000004 2 PMID:11940569 -1.1.1.51 nadh mesocricetus auratus 0.1 0.1 1 PMID:26002966 -1.1.1.51 nadp+ homo sapiens 1.3 1.3 1 PMID:11940569 -1.1.1.51 nadp+ mesocricetus auratus 0.15 0.15 1 PMID:26002966 -1.1.1.51 nerol mesocricetus auratus 0.023 0.023 1 PMID:26002966 -1.1.1.51 testosterone homo sapiens 3.4 3.4 1 PMID:11940569 -1.1.1.51 testosterone mesocricetus auratus 0.0078 0.0078 1 PMID:26002966 -1.1.1.51 trans-benzene dihydrodiol mesocricetus auratus 0.033 0.033 1 PMID:26002966 -1.1.1.53 20beta-hydroxyprogesterone mycobacterium tuberculosis 258.0 258.0 1 PMID:12524453 -1.1.1.53 5alpha-dihydrotestosterone homo sapiens 0.061 0.061 1 PMID:24434280 -1.1.1.53 androsterone mycobacterium tuberculosis 456.0 456.0 1 PMID:12524453 -1.1.1.53 cortisone streptomyces exfoliatus 0.333 0.333 1 * -1.1.1.53 progesterone homo sapiens 0.004 0.004 1 PMID:24434280 -1.1.1.53 progesterone mycobacterium tuberculosis 72.0 72.0 1 PMID:12524453 -1.1.1.53 progesterone streptomyces exfoliatus 6.67 6.67 1 * -1.1.1.54 (r)-pulegone nicotiana tabacum 3.3 3.3 1 PMID:17945329 -1.1.1.54 (s)-pulegone nicotiana tabacum 2.8 2.8 1 PMID:17945329 -1.1.1.56 d-ribitol sphingomonas sp. 29.0 29.0 1 PMID:32639976 -1.1.1.56 l-arabitol klebsiella aerogenes 28.0 28.0 1 PMID:4376942 -1.1.1.56 ribitol klebsiella aerogenes 299.0 299.0 1 PMID:4376942 -1.1.1.56 ribitol providencia alcalifaciens 10.0 10.0 1 PMID:26693956 -1.1.1.56 xylitol klebsiella aerogenes 36.0 36.0 1 PMID:4376942 -1.1.1.59 (r)-3-hydroxyisobutyrate candida albicans 1.31 1.31 1 PMID:24497638 -1.1.1.59 (s)-3-hydroxyisobutyrate candida albicans 2.48 2.48 1 PMID:24497638 -1.1.1.59 3-hydroxypropanoate bacillus cereus 0.21 0.21 1 PMID:19517068 -1.1.1.59 3-hydroxypropanoate candida albicans 30.97 30.97 1 PMID:24497638 -1.1.1.59 3-hydroxypropionate bacillus cereus 0.21 0.21 1 PMID:19517068 -1.1.1.59 l-serine candida albicans 9.41 9.41 1 PMID:24497638 -1.1.1.6 1,2-butanediol heyndrickxia coagulans 120.5 120.5 1 PMID:33020946 -1.1.1.6 1,3-butanediol escherichia coli 3.3 3.3 1 PMID:20585771 -1.1.1.6 1,3-butanediol klebsiella pneumoniae 2.6 2.6 1 PMID:20585771 -1.1.1.6 1,3-butanediol salmonella enterica 2.7 2.7 1 PMID:20585771 -1.1.1.6 3-(2,2,2-trifluoroethoxy)propane-1,2-diol geobacillus stearothermophilus 0.32 0.32 1 PMID:34123216 -1.1.1.6 3-[(propan-2-yl)oxy]propane-1,2-diol geobacillus stearothermophilus 0.3 0.3 1 PMID:34123216 -1.1.1.6 3-ethoxypropane-1,2-diol geobacillus stearothermophilus 0.19 0.19 1 PMID:34123216 -1.1.1.6 3-methoxypropane-1,2-diol geobacillus stearothermophilus 0.84 0.84 1 PMID:34123216 -1.1.1.6 3-phenoxypropane-1,2-diol geobacillus stearothermophilus 0.7 0.7 1 PMID:34123216 -1.1.1.6 3-propoxypropane-1,2-diol geobacillus stearothermophilus 0.27 0.27 1 PMID:34123216 -1.1.1.6 butane-2,3-diol klebsiella pneumoniae 22.5 22.5 1 PMID:31635443 -1.1.1.6 d-1,2-propanediol heyndrickxia coagulans 92.0 92.0 1 PMID:33020946 -1.1.1.6 d-2,3-butanediol heyndrickxia coagulans 50.5 50.5 1 PMID:33020946 -1.1.1.6 ethylene glycol klebsiella pneumoniae 2.8 2.8 1 PMID:31635443 -1.1.1.6 ethylene glycol klebsiella pneumoniae subsp. pneumoniae 2.8 2.8 1 PMID:31635443 -1.1.1.6 glycerol geobacillus stearothermophilus 7.4 7.4 1 PMID:34123216 -1.1.1.6 glycerol heyndrickxia coagulans 117.5 117.5 1 PMID:33020946 -1.1.1.6 glycerol klebsiella pneumoniae 87.1 3.36 3 PMID:27053034;PMID:31635443 -1.1.1.6 glycerol klebsiella pneumoniae subsp. pneumoniae 87.1 87.1 1 PMID:31635443 -1.1.1.6 glycerol thermoanaerobacterium thermosaccharolyticum 1.89 1.89 1 PMID:26975764 -1.1.1.6 glycerone thermoanaerobacterium thermosaccharolyticum 98.44 98.44 1 PMID:26975764 -1.1.1.6 nad+ klebsiella pneumoniae 70.6 70.6 1 PMID:31635443 -1.1.1.6 nad+ klebsiella pneumoniae subsp. pneumoniae 70.6 70.6 1 PMID:31635443 -1.1.1.6 pyruvate heyndrickxia coagulans 10.5 10.5 1 PMID:33020946 -1.1.1.6 racemic 2,3-butanediol klebsiella pneumoniae subsp. pneumoniae 22.5 22.5 1 PMID:31635443 -1.1.1.60 nadh pseudomonas putida 243.0 243.0 1 PMID:13900766 -1.1.1.61 succinate semialdehyde porphyromonas gingivalis 1329.0 1329.0 1 PMID:26432601 -1.1.1.62 (s)-indan-1-ol mus musculus 4.2 4.2 1 PMID:7737980 -1.1.1.62 17beta-estradiol homo sapiens 0.5 0.005775 4 PMID:25577493;PMID:27362750;PMID:30297283 -1.1.1.62 17beta-estradiol pseudomonas putida 2.1 2.1 1 PMID:30309659 -1.1.1.62 17beta-estradiol rhodococcus sp. p14 9.38 9.38 1 PMID:28619386 -1.1.1.62 5-androstene-3beta,17beta-diol homo sapiens 0.00032 0.00030000000000000003 2 PMID:27362750 -1.1.1.62 5alpha-androstane 3alpha,17beta-diol homo sapiens 3.0 3.0 1 PMID:25577493 -1.1.1.62 5alpha-dihydrotestosterone homo sapiens 0.0153 0.0153 1 PMID:30227243 -1.1.1.62 5alpha-dihydrotestosterone mus musculus 1.13 1.13 1 PMID:7737980 -1.1.1.62 allopregnanolone homo sapiens 0.1 0.1 1 PMID:30297283 -1.1.1.62 androsterone homo sapiens 1.7 1.7 1 PMID:25577493 -1.1.1.62 benzene diohydrodiol mus musculus 0.433 0.433 1 PMID:7737980 -1.1.1.62 dehydroepiandrosterone homo sapiens 0.16 0.16 1 PMID:16480815 -1.1.1.62 delta4-3,17-androstendione homo sapiens 1.1 1.1 1 PMID:25577493 -1.1.1.62 dihydrotestosterone homo sapiens 0.33 0.33 1 PMID:16480815 -1.1.1.62 estradiol-17beta homo sapiens 4.4 4.4 1 PMID:16480815 -1.1.1.62 estradiol-17beta mus musculus 0.95 0.95 1 PMID:7737980 -1.1.1.62 estrone homo sapiens 5.8 1.0 3 PMID:16480815;PMID:25577493;PMID:30227243 -1.1.1.62 estrone pseudomonas putida 0.89 0.89 1 PMID:30309659 -1.1.1.62 nadp+ curvularia lunata 0.65 0.65 2 PMID:16359545;PMID:17196285 -1.1.1.62 nadph curvularia lunata 3.8 3.8 2 PMID:16359545;PMID:17196285 -1.1.1.62 testosterone homo sapiens 0.6 0.6 1 PMID:25577493 -1.1.1.62 testosterone mus musculus 1.73 1.73 1 PMID:7737980 -1.1.1.64 4-oxo-2-nonenal homo sapiens 0.148 0.148 1 PMID:23165153 -1.1.1.67 d-arabinitol aspergillus fumigatus 162.0 162.0 1 PMID:21299839 -1.1.1.67 d-arabitol pseudomonas fluorescens 6.59 6.59 1 PMID:25752240 -1.1.1.67 d-fructose aspergillus fumigatus 86.0 86.0 1 PMID:21299839 -1.1.1.67 d-fructose pseudomonas fluorescens 61.0 40.5 2 PMID:12146981;PMID:20639204 -1.1.1.67 d-fructose thermotoga maritima 1.15 1.15 1 PMID:33233217 -1.1.1.67 d-fructose thermotoga neapolitana 180.0 94.5 2 PMID:33233217 -1.1.1.67 d-mannitol aspergillus fumigatus 212.0 212.0 1 PMID:21299839 -1.1.1.67 d-mannitol pseudomonas fluorescens 40.0 15.9 3 PMID:12146981;PMID:20639204;PMID:25752240 -1.1.1.67 d-xylulose aspergillus fumigatus 64.0 64.0 1 PMID:21299839 -1.1.1.67 l-sorbitol aspergillus fumigatus 60.0 60.0 1 PMID:21299839 -1.1.1.67 meso-erythritol pseudomonas fluorescens 0.599 0.599 1 PMID:25752240 -1.1.1.67 nad(p)h pseudomonas fluorescens 3.0 3.0 1 PMID:18082142 -1.1.1.67 nad+ pseudomonas fluorescens 40.0 30.0 2 PMID:10441145;PMID:19857201 -1.1.1.67 nadh pseudomonas fluorescens 61.0 54.0 3 PMID:10441145;PMID:18082142;PMID:19857201 -1.1.1.69 5-dehydro-d-gluconate aspergillus niger 3.7 3.7 2 PMID:29265364 -1.1.1.69 d-gluconate aspergillus niger 2.6 2.6 2 PMID:29265364 -1.1.1.71 (2s,5s)-2,5-hexanediol thermococcus sibiricus 2.2 2.2 1 PMID:24061874 -1.1.1.71 (rs)-1-phenylethanol thermococcus kodakarensis 35.7 35.7 1 PMID:23354700 -1.1.1.71 1-butanol pyrococcus horikoshii 0.48 0.48 1 PMID:28084552 -1.1.1.71 2,3-pentanedione thermococcus sibiricus 1.4 1.4 1 PMID:24061874 -1.1.1.71 2-propanol thermococcus sibiricus 0.53 0.53 2 PMID:20418438;PMID:24061874 -1.1.1.71 acetaldehyde acetivibrio thermocellus 240.0 220.0 3 PMID:26013492 -1.1.1.71 acetoin thermococcus kodakarensis 13.7 13.7 1 PMID:23354700 -1.1.1.71 butan-1-ol acinetobacter calcoaceticus 38.3 38.3 1 PMID:8162187 -1.1.1.71 butan-1-ol saccharomyces cerevisiae 50.6 50.6 1 PMID:8162187 -1.1.1.71 butanal acinetobacter calcoaceticus 26.3 26.3 1 PMID:8162187 -1.1.1.71 butanal pyrococcus horikoshii 0.82 0.82 1 PMID:28084552 -1.1.1.71 butanal saccharomyces cerevisiae 19.6 19.6 1 PMID:8162187 -1.1.1.71 d-xylose thermococcus sibiricus 0.7 0.7 2 PMID:20418438 -1.1.1.71 ethanol acinetobacter calcoaceticus 13.9 13.9 1 PMID:8162187 -1.1.1.71 ethanol saccharomyces cerevisiae 35.1 35.1 1 PMID:8162187 -1.1.1.71 heptan-1-ol acinetobacter calcoaceticus 38.9 38.9 1 PMID:8162187 -1.1.1.71 hexan-1-ol acinetobacter calcoaceticus 39.4 39.4 1 PMID:8162187 -1.1.1.71 hexan-1-ol saccharomyces cerevisiae 40.3 40.3 1 PMID:8162187 -1.1.1.71 meso-2,3-butanediol thermococcus kodakarensis 43.8 43.8 1 PMID:23354700 -1.1.1.71 nad+ pyrococcus horikoshii 0.5 0.5 1 PMID:28084552 -1.1.1.71 nad+ thermococcus kodakarensis 30.8 20.6 2 PMID:23354700 -1.1.1.71 nadh acetivibrio thermocellus 240.0 230.0 2 PMID:26013492 -1.1.1.71 nadh pyrococcus horikoshii 7.4 7.4 1 PMID:28084552 -1.1.1.71 nadh thermococcus kodakarensis 15.6 15.6 1 PMID:23354700 -1.1.1.71 nadp+ thermococcus kodakarensis 30.0 20.25 2 PMID:23354700 -1.1.1.71 nadp+ thermococcus sibiricus 2.02 0.45 3 PMID:20418438;PMID:24061874 -1.1.1.71 nadph acetivibrio thermocellus 280.0 280.0 1 PMID:26013492 -1.1.1.71 nadph pyrococcus horikoshii 7.87 7.87 1 PMID:28084552 -1.1.1.71 nadph thermococcus kodakarensis 17.3 17.3 1 PMID:23354700 -1.1.1.71 nadph thermococcus sibiricus 1.51 1.51 3 PMID:20418438;PMID:24061874 -1.1.1.71 octan-1-ol acinetobacter calcoaceticus 25.4 25.4 1 PMID:8162187 -1.1.1.71 octan-1-ol saccharomyces cerevisiae 39.8 39.8 1 PMID:8162187 -1.1.1.71 pentan-1-ol acinetobacter calcoaceticus 44.7 44.7 1 PMID:8162187 -1.1.1.71 pentan-1-ol saccharomyces cerevisiae 62.9 62.9 1 PMID:8162187 -1.1.1.71 pentanal pyrococcus horikoshii 6.96 6.96 1 PMID:28084552 -1.1.1.71 propanal pyrococcus horikoshii 6.66 6.66 1 PMID:28084552 -1.1.1.71 pyruvaldehyde thermococcus sibiricus 2.04 2.04 2 PMID:20418438;PMID:24061874 -1.1.1.72 nadph gluconobacter oxydans 57.2 57.2 1 PMID:20887732 -1.1.1.76 (2s)-acetoin bacillus licheniformis 202.0 202.0 1 PMID:26494135 -1.1.1.76 (2s,3s)-butane-2,3-diol klebsiella pneumoniae 3.51 3.51 1 PMID:28875495 -1.1.1.76 (r,r)-butane-2,3-diol bacillus licheniformis 591.0 591.0 1 PMID:26494135 -1.1.1.76 (r,s)-acetoin mycobacterium sp. 6.0 6.0 1 PMID:25082080 -1.1.1.76 diacetyl bacillus licheniformis 1222.0 1222.0 1 PMID:26494135 -1.1.1.79 glycolate acetobacter aceti 10.0 7.4 2 PMID:32729375 -1.1.1.79 glyoxylate acetobacter aceti 570.0 550.0 2 PMID:32729375 -1.1.1.79 glyoxylate arabidopsis thaliana 3407.0 25.45 6 PMID:18495639;PMID:24076009;PMID:28855911 -1.1.1.79 glyoxylate homo sapiens 67.0 47.0 4 PMID:16198644 -1.1.1.79 glyoxylate malus domestica 30.9 25.0 2 PMID:28855911 -1.1.1.79 glyoxylate oryza sativa 33.7 22.25 2 PMID:28855911 -1.1.1.79 glyoxylate thermus thermophilus 76000.0 70500.0 2 PMID:18302405 -1.1.1.79 glyoxylate thermus thermophilus hb27 760000.0 705000.0 2 PMID:18302405 -1.1.1.79 hydroxypyruvate homo sapiens 65.0 51.5 4 PMID:16198644 -1.1.1.79 nadh pyrococcus horikoshii ot3 11.0 7.55 2 PMID:17327673 -1.1.1.79 nadh thermus thermophilus 22000.0 22000.0 1 PMID:18302405 -1.1.1.79 nadh thermus thermophilus hb27 220000.0 220000.0 1 PMID:18302405 -1.1.1.79 nadph arabidopsis thaliana 84.1 10.7 9 PMID:18495639;PMID:24076009;PMID:28855911 -1.1.1.79 nadph malus domestica 22.3 12.149999999999999 4 PMID:28855911 -1.1.1.79 nadph oryza sativa 14.2 9.8 4 PMID:28855911 -1.1.1.79 nadph pyrococcus horikoshii ot3 2.4 2.1 2 PMID:17327673 -1.1.1.79 nadph thermus thermophilus 30000.0 30000.0 1 PMID:18302405 -1.1.1.79 nadph thermus thermophilus hb27 300000.0 300000.0 1 PMID:18302405 -1.1.1.79 succinic semialdehyde arabidopsis thaliana 17.0 17.0 4 PMID:18495639;PMID:28855911 -1.1.1.79 succinic semialdehyde malus domestica 10.3 7.45 2 PMID:28855911 -1.1.1.79 succinic semialdehyde oryza sativa 21.9 14.549999999999999 2 PMID:28855911 -1.1.1.8 dihydroxyacetone phosphate ceratitis capitata 188.0 188.0 1 PMID:14695 -1.1.1.8 dihydroxyacetone phosphate homo sapiens 240.0 240.0 1 PMID:26926520 -1.1.1.8 dihydroxyacetone phosphate oryctolagus cuniculus 390.0 367.5 2 * -1.1.1.8 glycerone phosphate eidolon helvum 19000.0 19000.0 1 PMID:12689513 -1.1.1.8 glycerone phosphate homo sapiens 240.0 240.0 1 PMID:26926520 -1.1.1.8 l-glycerol-3-phosphate eidolon helvum 78.0 64.5 2 PMID:12689513 -1.1.1.8 sn-glycerol 3-phosphate ceratitis capitata 32.0 32.0 1 PMID:14695 -1.1.1.80 n-butanol aspergillus fumigatus 0.22 0.22 1 PMID:31301008 -1.1.1.80 propan-2-ol aspergillus fumigatus 0.066 0.066 1 PMID:31301008 -1.1.1.81 3-hydroxypyruvate methylococcus capsulatus 42.0 40.0 2 PMID:29223156 -1.1.1.81 3-hydroxypyruvate methylosinus trichosporium 687.0 487.5 2 PMID:29223156 -1.1.1.81 3-hydroxypyruvate methylotuvimicrobium alcaliphilum 48.0 39.0 2 PMID:29223156 -1.1.1.81 4-hydroxyphenylpyruvate arabidopsis thaliana 0.122 0.122 1 PMID:30233632 -1.1.1.81 glyoxylate methylococcus capsulatus 41.0 41.0 1 PMID:29223156 -1.1.1.81 glyoxylate methylosinus trichosporium 166.0 109.0 2 PMID:29223156 -1.1.1.81 glyoxylate methylotuvimicrobium alcaliphilum 88.0 53.5 2 PMID:29223156 -1.1.1.81 hydroxypyruvate arabidopsis thaliana 0.93 0.927 3 PMID:30233632 -1.1.1.81 hydroxypyruvate pyrococcus furiosus 10.0 5.6 2 PMID:26865263 -1.1.1.81 hydroxypyruvate pyrococcus horikoshii 4.5 2.55 2 PMID:26865263 -1.1.1.81 hydroxypyruvate pyrococcus yayanosii 25.0 15.75 2 PMID:26865263 -1.1.1.81 nadh methylococcus capsulatus 42.0 41.5 2 PMID:29223156 -1.1.1.81 nadh methylosinus trichosporium 687.0 426.5 2 PMID:29223156 -1.1.1.81 nadh methylotuvimicrobium alcaliphilum 19.0 16.5 2 PMID:29223156 -1.1.1.81 nadh pyrococcus horikoshii ot3 11.0 7.55 2 PMID:17327673 -1.1.1.81 nadph methylococcus capsulatus 23.0 23.0 1 PMID:29223156 -1.1.1.81 nadph methylosinus trichosporium 284.0 168.0 2 PMID:29223156 -1.1.1.81 nadph methylotuvimicrobium alcaliphilum 88.0 68.0 2 PMID:29223156 -1.1.1.81 nadph pyrococcus horikoshii ot3 2.4 2.1 2 PMID:17327673 -1.1.1.81 phenylpyruvate arabidopsis thaliana 0.61 0.033 3 PMID:30233632 -1.1.1.82 (2s,3r)-tartrate aeropyrum pernix 0.2 0.18 2 PMID:19555779 -1.1.1.82 (2s,3s)-tartrate aeropyrum pernix 4.1 2.235 2 PMID:19555779 -1.1.1.82 (s)-malate aeropyrum pernix 2.6 2.0 2 PMID:19555779 -1.1.1.82 (s)-malate sorghum sp. 233.0 233.0 1 PMID:8665917 -1.1.1.82 oxaloacetate sorghum sp. 1520.0 1520.0 1 PMID:8665917 -1.1.1.85 (2r,3s)-3-isopropylmalate acidithiobacillus ferrooxidans 28.0 28.0 1 PMID:9532798 -1.1.1.85 (2r,3s)-3-isopropylmalate arabidopsis thaliana 9.05 5.395 4 PMID:21697089;PMID:27137927 -1.1.1.85 (2r,3s)-3-isopropylmalate escherichia coli 12.0 12.0 1 PMID:32412093 -1.1.1.85 (2r,3s)-3-isopropylmalate shewanella benthica 17.0 14.0 7 PMID:19897891;PMID:26847201 -1.1.1.85 (2r,3s)-3-isopropylmalate shewanella oneidensis 17.4 8.4 7 PMID:19897891;PMID:26847201 -1.1.1.85 (2r,3s)-3-isopropylmalate sulfolobus acidocaldarius 8.5 8.5 1 PMID:27590116 -1.1.1.85 (2r,3s)-3-isopropylmalate synthetic construct 22.0 4.449999999999999 6 PMID:32968141 -1.1.1.85 (2r,3s)-3-isopropylmalate thermus thermophilus 163.0 4.835 10 PMID:11297666;PMID:20735360;PMID:23421786;PMID:25497013;PMID:26731489;PMID:8550506;PMID:9237617 -1.1.1.85 3-(2'-methylthio)ethylmalate arabidopsis thaliana 0.85 0.0167 3 PMID:21697089 -1.1.1.85 3-ethylmalate acidithiobacillus ferrooxidans 38.0 38.0 1 PMID:9532798 -1.1.1.85 3-isoamylmalate acidithiobacillus ferrooxidans 20.0 20.0 1 PMID:9532798 -1.1.1.85 3-isopropylmalate bacillus subtilis 14.9 14.9 1 PMID:17389690 -1.1.1.85 3-isopropylmalate sulfurisphaera tokodaii 6.9 6.9 1 PMID:18854331 -1.1.1.85 3-methylmalate acidithiobacillus ferrooxidans 28.0 28.0 1 PMID:9532798 -1.1.1.85 3-tert-butylmalate acidithiobacillus ferrooxidans 2.7 2.7 1 PMID:9532798 -1.1.1.85 d-3-ethylmalate sulfurisphaera tokodaii 3.1 3.1 1 PMID:9023199 -1.1.1.85 d-3-isobutylmalate sulfurisphaera tokodaii 3.1 3.1 1 PMID:9023199 -1.1.1.85 d-3-isopentylmalate sulfurisphaera tokodaii 2.7 2.7 1 PMID:9023199 -1.1.1.85 d-3-isopropylmalate sulfurisphaera tokodaii 3.6 3.6 1 PMID:9023199 -1.1.1.85 d-3-methylmalate sulfurisphaera tokodaii 3.5 3.5 1 PMID:9023199 -1.1.1.85 d-3-t-butylmalate sulfurisphaera tokodaii 0.96 0.96 1 PMID:9023199 -1.1.1.85 d-malate escherichia coli 0.41 0.41 1 PMID:32412093 -1.1.1.85 ethylmalate escherichia coli 70.0 70.0 1 PMID:9003442 -1.1.1.85 homoisocitrate sulfolobus acidocaldarius 0.26 0.26 1 PMID:27590116 -1.1.1.85 isopropylmalate escherichia coli 69.0 69.0 1 PMID:9003442 -1.1.1.85 isopropylmalate thermus thermophilus 19.0 0.96 6 PMID:8535253;PMID:8901552;PMID:9003442 -1.1.1.85 malate acidithiobacillus ferrooxidans 5.0 5.0 1 PMID:9532798 -1.1.1.85 malate sulfurisphaera tokodaii 4.0 4.0 1 PMID:9023199 -1.1.1.85 malate thermus thermophilus 10.6 7.645 2 PMID:8535253 -1.1.1.85 nad+ escherichia coli 69.0 69.0 1 PMID:9003442 -1.1.1.85 nad+ shewanella benthica 18.7 18.7 1 PMID:26847201 -1.1.1.85 nad+ shewanella oneidensis 17.1 17.1 1 PMID:26847201 -1.1.1.85 nad+ synthetic construct 22.0 4.449999999999999 6 PMID:32968141 -1.1.1.85 nad+ thermus thermophilus 163.0 10.3 16 PMID:11297666;PMID:12082165;PMID:16797545;PMID:31249343;PMID:8535253;PMID:8550506;PMID:8901552;PMID:9003442;PMID:9237617 -1.1.1.85 nadp+ thermus thermophilus 4.69 0.96 4 PMID:8535253;PMID:8901552 -1.1.1.85 tartrate thermus thermophilus 0.19 0.14500000000000002 2 PMID:8535253 -1.1.1.85 tert-butylmalate escherichia coli 6.0 6.0 1 PMID:9003442 -1.1.1.86 (2s)-2-acetolactate corynebacterium glutamicum 0.235 0.235 1 PMID:31298526 -1.1.1.86 (2s)-2-acetolactate mycobacterium tuberculosis 3.7 3.7 1 PMID:32745463 -1.1.1.86 (2s)-2-acetolactate staphylococcus aureus 0.00023 0.00023 1 PMID:28975665 -1.1.1.86 (s)-2-acetolactate meiothermus ruber 1.09 0.93 2 PMID:25446654 -1.1.1.86 (s)-2-acetolactate mycobacterium tuberculosis 1.4 1.4 1 PMID:26876563 -1.1.1.86 (s)-2-acetolactate saccharolobus solfataricus 0.013 0.012 2 PMID:30921515 -1.1.1.86 (s)-2-acetolactate staphylococcus aureus 0.00023 0.00023 1 PMID:28975665 -1.1.1.86 (s)-2-acetolactate sulfolobus acidocaldarius 0.957 0.178 12 PMID:29739976 -1.1.1.86 2,3-dihydroxy-3-methylbutanoate escherichia coli 0.00417 0.00417 1 PMID:2189496 -1.1.1.86 2-aceto-2-hydroxybutyrate salmonella enterica subsp. enterica serovar typhimurium 78.3 78.3 1 PMID:803501 -1.1.1.86 2-acetolactate campylobacter jejuni 0.7 0.7 1 PMID:32745463 -1.1.1.86 2-acetolactate escherichia coli 2.231 1.8 3 PMID:15654896;PMID:2189496;PMID:27136273 -1.1.1.86 2-acetolactate oryza sativa 1.4 1.4 1 PMID:27136273 -1.1.1.86 2-acetolactate salmonella enterica subsp. enterica serovar typhimurium 18.3 18.3 1 PMID:803501 -1.1.1.86 2-hydroxy-2-ethyl-3-oxobutanoate corynebacterium glutamicum 0.9 0.9 1 PMID:25296650 -1.1.1.86 2-hydroxy-2-ethyl-3-oxobutanoate escherichia coli 3.5 3.5 1 PMID:25296650 -1.1.1.86 2-hydroxy-2-ethyl-3-oxobutanoate streptomyces ambofaciens 1.3 1.3 1 PMID:25296650 -1.1.1.86 2-hydroxy-2-ethyl-3-oxobutanoate streptomyces avermitilis 0.4 0.4 1 PMID:25296650 -1.1.1.86 2-hydroxy-2-ethyl-3-oxobutanoate streptomyces coelicolor 3.2 1.7950000000000002 2 PMID:25296650 -1.1.1.86 2-hydroxy-2-ethyl-3-oxobutanoate streptomyces griseus 0.44 0.44 1 PMID:25296650 -1.1.1.86 2-hydroxy-2-ethyl-3-oxobutanoate streptomyces lividans 3.6 1.86 2 PMID:25296650 -1.1.1.86 2-hydroxy-2-ethyl-3-oxobutanoate streptomyces pristinaespiralis 0.18 0.18 1 PMID:25296650 -1.1.1.86 2-hydroxy-2-ethyl-3-oxobutanoate streptomyces viridifaciens 0.3 0.3 1 PMID:25296650 -1.1.1.86 2-hydroxy-2-methyl-3-oxobutanoate corynebacterium glutamicum 3.2 3.2 1 PMID:25296650 -1.1.1.86 2-hydroxy-2-methyl-3-oxobutanoate escherichia coli 2.0 2.0 1 PMID:25296650 -1.1.1.86 2-hydroxy-2-methyl-3-oxobutanoate streptomyces ambofaciens 0.63 0.63 1 PMID:25296650 -1.1.1.86 2-hydroxy-2-methyl-3-oxobutanoate streptomyces avermitilis 0.24 0.24 1 PMID:25296650 -1.1.1.86 2-hydroxy-2-methyl-3-oxobutanoate streptomyces coelicolor 1.1 0.67 2 PMID:25296650 -1.1.1.86 2-hydroxy-2-methyl-3-oxobutanoate streptomyces griseus 0.42 0.42 1 PMID:25296650 -1.1.1.86 2-hydroxy-2-methyl-3-oxobutanoate streptomyces lividans 0.7 0.49 2 PMID:25296650 -1.1.1.86 2-hydroxy-2-methyl-3-oxobutanoate streptomyces pristinaespiralis 3.6 3.6 1 PMID:25296650 -1.1.1.86 2-hydroxy-2-methyl-3-oxobutanoate streptomyces viridifaciens 2.0 2.0 1 PMID:25296650 -1.1.1.86 2-ketobutyrate escherichia coli 0.167 0.167 1 PMID:15654896 -1.1.1.86 2-ketoisovalerate escherichia coli 0.182 0.182 1 PMID:15654896 -1.1.1.86 2-ketopantoate escherichia coli 0.194 0.194 1 PMID:15654896 -1.1.1.86 2-ketovalerate escherichia coli 0.05 0.05 1 PMID:15654896 -1.1.1.86 2-methylacetoacetate corynebacterium glutamicum 0.4 0.4 1 PMID:25296650 -1.1.1.86 2-methylacetoacetate streptomyces ambofaciens 1.2 1.2 1 PMID:25296650 -1.1.1.86 2-methylacetoacetate streptomyces avermitilis 1.8 1.8 1 PMID:25296650 -1.1.1.86 2-methylacetoacetate streptomyces coelicolor 1.0 0.8 2 PMID:25296650 -1.1.1.86 2-methylacetoacetate streptomyces griseus 1.05 1.05 1 PMID:25296650 -1.1.1.86 2-methylacetoacetate streptomyces lividans 0.67 0.585 2 PMID:25296650 -1.1.1.86 2-methylacetoacetate streptomyces pristinaespiralis 2.0 2.0 1 PMID:25296650 -1.1.1.86 2-methylacetoacetate streptomyces viridifaciens 2.0 2.0 1 PMID:25296650 -1.1.1.86 3-hydroxy-2-ketobutyrate escherichia coli 0.594 0.594 1 PMID:15654896 -1.1.1.86 3-hydroxy-3-ethyl-2-oxobutanoate corynebacterium glutamicum 0.18 0.18 1 PMID:25296650 -1.1.1.86 3-hydroxy-3-ethyl-2-oxobutanoate escherichia coli 3.8 3.8 1 PMID:25296650 -1.1.1.86 3-hydroxy-3-ethyl-2-oxobutanoate streptomyces ambofaciens 0.9 0.9 1 PMID:25296650 -1.1.1.86 3-hydroxy-3-ethyl-2-oxobutanoate streptomyces avermitilis 0.8 0.8 1 PMID:25296650 -1.1.1.86 3-hydroxy-3-ethyl-2-oxobutanoate streptomyces coelicolor 1.8 1.3 2 PMID:25296650 -1.1.1.86 3-hydroxy-3-ethyl-2-oxobutanoate streptomyces griseus 1.0 1.0 1 PMID:25296650 -1.1.1.86 3-hydroxy-3-ethyl-2-oxobutanoate streptomyces lividans 1.3 1.1 2 PMID:25296650 -1.1.1.86 3-hydroxy-3-ethyl-2-oxobutanoate streptomyces pristinaespiralis 1.4 1.4 1 PMID:25296650 -1.1.1.86 3-hydroxy-3-ethyl-2-oxobutanoate streptomyces viridifaciens 0.5 0.5 1 PMID:25296650 -1.1.1.86 3-hydroxy-3-methyl-2-ketobutyrate escherichia coli 3.511 3.511 1 PMID:15654896 -1.1.1.86 3-hydroxy-3-methyl-2-oxobutanoate corynebacterium glutamicum 0.9 0.9 1 PMID:25296650 -1.1.1.86 3-hydroxy-3-methyl-2-oxobutanoate escherichia coli 3.1 3.1 1 PMID:25296650 -1.1.1.86 3-hydroxy-3-methyl-2-oxobutanoate streptomyces ambofaciens 0.8 0.8 1 PMID:25296650 -1.1.1.86 3-hydroxy-3-methyl-2-oxobutanoate streptomyces avermitilis 1.2 1.2 1 PMID:25296650 -1.1.1.86 3-hydroxy-3-methyl-2-oxobutanoate streptomyces coelicolor 2.2 1.25 2 PMID:25296650 -1.1.1.86 3-hydroxy-3-methyl-2-oxobutanoate streptomyces griseus 0.5 0.5 1 PMID:25296650 -1.1.1.86 3-hydroxy-3-methyl-2-oxobutanoate streptomyces lividans 2.8 1.5999999999999999 2 PMID:25296650 -1.1.1.86 3-hydroxy-3-methyl-2-oxobutanoate streptomyces pristinaespiralis 5.2 5.2 1 PMID:25296650 -1.1.1.86 3-hydroxy-3-methyl-2-oxobutanoate streptomyces viridifaciens 2.5 2.5 1 PMID:25296650 -1.1.1.86 3-hydroxypyruvate escherichia coli 26.0 15.688 2 PMID:15654896;PMID:27136273 -1.1.1.86 3-hydroxypyruvate mycobacterium tuberculosis 12.5 12.5 1 PMID:26876563 -1.1.1.86 3-hydroxypyruvate oryza sativa 4.5 4.5 1 PMID:27136273 -1.1.1.86 hydroxypyruvate campylobacter jejuni 0.3 0.3 1 PMID:32745463 -1.1.1.86 hydroxypyruvate corynebacterium glutamicum 0.5 0.5 1 PMID:25296650 -1.1.1.86 hydroxypyruvate mycobacterium tuberculosis 0.2 0.2 1 PMID:32745463 -1.1.1.86 hydroxypyruvate streptomyces ambofaciens 1.0 1.0 1 PMID:25296650 -1.1.1.86 hydroxypyruvate streptomyces avermitilis 2.0 2.0 1 PMID:25296650 -1.1.1.86 hydroxypyruvate streptomyces coelicolor 0.5 0.5 1 PMID:25296650 -1.1.1.86 hydroxypyruvate streptomyces griseus 1.5 1.5 1 PMID:25296650 -1.1.1.86 hydroxypyruvate streptomyces lividans 0.7 0.7 1 PMID:25296650 -1.1.1.86 hydroxypyruvate streptomyces pristinaespiralis 2.0 2.0 1 PMID:25296650 -1.1.1.86 hydroxypyruvate streptomyces viridifaciens 2.0 2.0 1 PMID:25296650 -1.1.1.86 nadh alicyclobacillus acidocaldarius subsp. acidocaldarius 0.26 0.26 1 PMID:23776225 -1.1.1.86 nadh corynebacterium glutamicum 0.0027 0.0027 1 PMID:31298526 -1.1.1.86 nadh escherichia coli 0.00183 0.00183 1 PMID:9015391 -1.1.1.86 nadh methanococcus aeolicus 0.3 0.3 1 PMID:23776225 -1.1.1.86 nadh saccharolobus solfataricus 0.01 0.01 1 PMID:30921515 -1.1.1.86 nadh sulfolobus acidocaldarius 0.056 0.056 1 PMID:29739976 -1.1.1.86 nadph alicyclobacillus acidocaldarius subsp. acidocaldarius 0.66 0.66 1 PMID:23776225 -1.1.1.86 nadph corynebacterium glutamicum 0.228 0.228 1 PMID:31298526 -1.1.1.86 nadph escherichia coli 0.12 0.12 1 PMID:9015391 -1.1.1.86 nadph meiothermus ruber 0.98 0.98 1 PMID:25446654 -1.1.1.86 nadph methanococcus aeolicus 0.7 0.7 1 PMID:23776225 -1.1.1.86 nadph saccharolobus solfataricus 0.01 0.01 1 PMID:30921515 -1.1.1.86 nadph streptococcus pneumoniae 0.1 0.1 1 * -1.1.1.86 nadph sulfolobus acidocaldarius 0.064 0.064 1 PMID:29739976 -1.1.1.86 pyruvate corynebacterium glutamicum 8.6 8.6 1 PMID:25296650 -1.1.1.86 pyruvate escherichia coli 0.021 0.021 1 PMID:15654896 -1.1.1.86 pyruvate streptomyces ambofaciens 6.3 6.3 1 PMID:25296650 -1.1.1.86 pyruvate streptomyces avermitilis 3.6 3.6 1 PMID:25296650 -1.1.1.86 pyruvate streptomyces coelicolor 5.6 4.199999999999999 2 PMID:25296650 -1.1.1.86 pyruvate streptomyces griseus 1.0 1.0 1 PMID:25296650 -1.1.1.86 pyruvate streptomyces lividans 6.7 4.85 2 PMID:25296650 -1.1.1.86 pyruvate streptomyces pristinaespiralis 3.0 3.0 1 PMID:25296650 -1.1.1.86 pyruvate streptomyces viridifaciens 5.7 5.7 1 PMID:25296650 -1.1.1.87 (1r,2s)-1-hydroxybutane-1,2,4-tricarboxylate candida albicans 0.4 0.39 2 PMID:23107040 -1.1.1.87 (2r,3s)-3-(2-hydroxyethyl)malate deinococcus radiodurans 25.0 25.0 1 PMID:17116397 -1.1.1.87 (2r,3s)-3-(2-hydroxyethyl)malate saccharomyces cerevisiae 0.78 0.78 1 PMID:17116397 -1.1.1.87 (2r,3s)-3-(3-hydroxypropyl)malate deinococcus radiodurans 29.0 29.0 1 PMID:17116397 -1.1.1.87 (2r,3s)-3-(3-hydroxypropyl)malate saccharomyces cerevisiae 4.8 4.8 1 PMID:17116397 -1.1.1.87 (2r,3s)-3-(4-hydroxybutyl)malate deinococcus radiodurans 8.0 8.0 1 PMID:17116397 -1.1.1.87 (2r,3s)-3-(4-hydroxybutyl)malate saccharomyces cerevisiae 2.1 2.1 1 PMID:17116397 -1.1.1.87 (2r,3s)-3-(4-pentenyl)malic acid deinococcus radiodurans 3.0 3.0 1 PMID:17116397 -1.1.1.87 (2r,3s)-3-(4-pentenyl)malic acid saccharomyces cerevisiae 0.14 0.14 1 PMID:17116397 -1.1.1.87 (2r,3s)-3-allylmalic acid deinococcus radiodurans 37.0 37.0 1 PMID:17116397 -1.1.1.87 (2r,3s)-3-allylmalic acid saccharomyces cerevisiae 0.34 0.34 1 PMID:17116397 -1.1.1.87 (2r,3s)-3-propylmalic acid deinococcus radiodurans 53.0 53.0 1 PMID:17116397 -1.1.1.87 (2r,3s)-3-propylmalic acid saccharomyces cerevisiae 0.7 0.7 1 PMID:17116397 -1.1.1.87 1-hydroxy-1,2,3-propanetricarboxylate thermus thermophilus 171.0 171.0 1 PMID:12427751 -1.1.1.87 1-hydroxy-1,2,4-butanetricarboxylate thermus thermophilus 171.0 171.0 1 PMID:12427751 -1.1.1.87 3-isopropylmalate deinococcus radiodurans 0.371 0.371 1 PMID:16139794 -1.1.1.87 3-isopropylmalate thermococcus kodakarensis 4.8 4.8 1 PMID:27831491 -1.1.1.87 3-vinylmalate deinococcus radiodurans 0.77 0.77 1 PMID:17116397 -1.1.1.87 3-vinylmalate saccharomyces cerevisiae 0.5 0.5 1 PMID:17116397 -1.1.1.87 d-malate thermococcus kodakarensis 0.099 0.099 1 PMID:27831491 -1.1.1.87 ethylmalate deinococcus radiodurans 43.0 43.0 1 PMID:17116397 -1.1.1.87 ethylmalate saccharomyces cerevisiae 0.61 0.61 1 PMID:17116397 -1.1.1.87 homoisocitrate deinococcus radiodurans 46.2 46.1 2 PMID:16139794;PMID:17116397 -1.1.1.87 homoisocitrate pyrococcus horikoshii 13.7 13.7 1 PMID:15845397 -1.1.1.87 homoisocitrate saccharomyces cerevisiae 17.0 17.0 1 PMID:17116397 -1.1.1.87 homoisocitrate thermococcus kodakarensis 17.0 14.5 2 PMID:27831491 -1.1.1.87 isocitrate deinococcus radiodurans 43.0 42.9 2 PMID:16139794;PMID:17116397 -1.1.1.87 isocitrate pyrococcus horikoshii 14.8 14.8 1 PMID:15845397 -1.1.1.87 isocitrate thermococcus kodakarensis 5.0 5.0 1 PMID:27831491 -1.1.1.87 isocitrate thermus thermophilus 438.0 438.0 1 PMID:16166541 -1.1.1.87 isopropylmalate deinococcus radiodurans 0.37 0.37 1 PMID:17116397 -1.1.1.87 nad+ candida albicans 0.4 0.39 2 PMID:23107040 -1.1.1.87 nad+ thermococcus kodakarensis 17.0 4.9 4 PMID:27831491 -1.1.1.87 nadp+ thermococcus kodakarensis 12.0 12.0 1 PMID:27831491 -1.1.1.87 trisodium (2s,3r)-2-(carboxylatomethoxy)-3-hydroxybutanedioate saccharomyces cerevisiae 0.59 0.59 1 PMID:18086528 -1.1.1.87 trisodium (2s,3r)-2-[(carboxylatomethyl)amino]-3-hydroxybutanedioate saccharomyces cerevisiae 2.0 2.0 1 PMID:18086528 -1.1.1.88 3-hydroxy-3-methylglutaryl-coa delftia acidovorans 22.3 22.3 1 PMID:30199631 -1.1.1.88 nadh delftia acidovorans 16.6 16.6 1 PMID:30199631 -1.1.1.9 d-fructose [candida] sp. ha 167 920.0 920.0 1 PMID:12604239 -1.1.1.9 d-ribulose blastobotrys adeninivorans 74.0 74.0 1 PMID:15803389 -1.1.1.9 d-sorbitol [candida] sp. ha 167 114.0 114.0 1 PMID:12604239 -1.1.1.9 d-sorbitol blastobotrys adeninivorans 528.0 528.0 1 PMID:15803389 -1.1.1.9 d-sorbitol meyerozyma caribbica 8.28 8.28 1 PMID:27506274 -1.1.1.9 d-sorbitol ovis aries 8.0 8.0 1 PMID:17343568 -1.1.1.9 d-xylulose [candida] sp. ha 167 1800.0 1650.0 2 PMID:12604239 -1.1.1.9 d-xylulose blastobotrys adeninivorans 302.9 302.9 1 PMID:15803389 -1.1.1.9 l-arabitol meyerozyma caribbica 3.35 3.35 1 PMID:27506274 -1.1.1.9 l-sorbose blastobotrys adeninivorans 216.0 216.0 1 PMID:15803389 -1.1.1.9 nad+ gluconobacter oxydans 27.2 27.2 1 PMID:16531240 -1.1.1.9 nad+ meyerozyma caribbica 18.5 18.5 1 PMID:27506274 -1.1.1.9 nad+ rhizomucor pusillus 6.35 6.35 1 PMID:25082263 -1.1.1.9 nad+ scheffersomyces stipitis 17.5 17.5 1 PMID:15623532 -1.1.1.9 nadp+ meyerozyma caribbica 3.27 3.27 1 PMID:27506274 -1.1.1.9 nadp+ scheffersomyces stipitis 1.83 1.83 1 PMID:15623532 -1.1.1.9 ribitol meyerozyma caribbica 4.48 4.48 1 PMID:27506274 -1.1.1.9 sorbitol [candida] sp. ha 167 161.0 161.0 1 PMID:17343568 -1.1.1.9 xylitol [candida] sp. ha 167 170.0 156.5 2 PMID:12604239 -1.1.1.9 xylitol blastobotrys adeninivorans 2644.0 2379.5 2 PMID:15803389 -1.1.1.9 xylitol gluconobacter oxydans 24.6 24.6 1 PMID:16531240 -1.1.1.9 xylitol meyerozyma caribbica 18.0 18.0 1 PMID:27506274 -1.1.1.9 xylitol pichia kudriavzevii 15.015 15.015 1 PMID:32171656 -1.1.1.9 xylitol rhizomucor pusillus 11.1 11.1 1 PMID:25082263 -1.1.1.9 xylitol scheffersomyces stipitis 19.62 19.62 1 PMID:32171656 -1.1.1.9 xylitol torulaspora delbrueckii 13.28 13.28 1 PMID:32171656 -1.1.1.90 3-methoxybenzyl alcohol acinetobacter calcoaceticus 156.0 156.0 1 PMID:3060114 -1.1.1.90 3-methyl-2-buten-1-ol acinetobacter calcoaceticus 41.0 39.0 2 PMID:10334943 -1.1.1.90 4-hydroxybenzyl alcohol acinetobacter calcoaceticus 80.0 80.0 1 PMID:3060114 -1.1.1.90 4-isopropylbenzyl alcohol acinetobacter calcoaceticus 144.0 144.0 1 PMID:3060114 -1.1.1.90 4-methoxybenzyl alcohol acinetobacter calcoaceticus 116.0 116.0 1 PMID:3060114 -1.1.1.90 benzaldehyde acinetobacter baylyi 12940.0 12940.0 1 PMID:23042182 -1.1.1.90 benzaldehyde pseudomonas putida 622.0 622.0 1 PMID:2202600 -1.1.1.90 benzyl alcohol acinetobacter calcoaceticus 131.0 97.0 2 PMID:10334943;PMID:3060114 -1.1.1.90 benzyl alcohol lactiplantibacillus plantarum wcfs1 3.4 3.4 1 PMID:18510336 -1.1.1.90 benzyl alcohol pseudomonas putida 228.0 123.0 2 PMID:10334943;PMID:2202600 -1.1.1.90 benzyl alcohol thauera sp. 85.0 85.0 1 PMID:7575097 -1.1.1.90 cinnamyl alcohol acinetobacter calcoaceticus 141.0 141.0 1 PMID:3060114 -1.1.1.90 cinnamyl alcohol streptomyces sp. 116.0 116.0 1 PMID:21897026 -1.1.1.90 coniferyl alcohol streptomyces sp. 69.7 69.7 3 PMID:21897026;PMID:23500723 -1.1.1.90 coniferyl aldehyde streptomyces sp. 354.0 354.0 1 PMID:21897026 -1.1.1.90 nad+ streptomyces sp. 53.7 53.7 1 PMID:21897026 -1.1.1.90 nadh acinetobacter baylyi 8920.0 8920.0 1 PMID:23042182 -1.1.1.90 perillyl alcohol acinetobacter calcoaceticus 83.0 83.0 1 PMID:3060114 -1.1.1.91 (r)-1-phenylethanol ralstonia sp. 0.0047 0.0047 1 PMID:23686719 -1.1.1.91 (s)-1-phenylethanol ralstonia sp. 0.0115 0.0115 1 PMID:23686719 -1.1.1.91 (s)-2-octanol cupriavidus necator 13.7 9.0 2 PMID:26812656 -1.1.1.91 3,4-dimethoxybenzaldehyde phanerodontia chrysosporium 8.833 8.8315 2 PMID:22742413;PMID:29079624 -1.1.1.91 3,4-dimethoxybenzaldehyde saccharomyces cerevisiae 2.37 2.37 1 PMID:29079624 -1.1.1.91 3,4-dimethoxybenzyl alcohol phanerodontia chrysosporium 2.55 2.55 1 PMID:22742413 -1.1.1.91 3,5-dimethoxybenzaldehyde phanerodontia chrysosporium 9.83 9.83 1 PMID:22742413 -1.1.1.91 3-hydroxy-4-methoxy-benzaldehyde phanerodontia chrysosporium 3.83 3.83 1 PMID:22742413 -1.1.1.91 4-hydroxy-3-methoxy-benzaldehyde phanerodontia chrysosporium 3.33 3.33 1 PMID:22742413 -1.1.1.91 4-hydroxy-3-methoxy-benzyl alcohol phanerodontia chrysosporium 4.33 4.33 1 PMID:22742413 -1.1.1.91 4-methoxybenzaldehyde phanerodontia chrysosporium 8.16 8.16 1 PMID:22742413 -1.1.1.91 4-nitrobenzaldehyde saccharomyces cerevisiae 0.37 0.37 1 PMID:29079624 -1.1.1.91 5-(hydroxymethyl)-2-furaldehyde phanerodontia chrysosporium 2.93 2.93 1 PMID:22742413 -1.1.1.91 benzaldehyde phanerodontia chrysosporium 7.17 7.165 2 PMID:22742413;PMID:29079624 -1.1.1.91 benzaldehyde yokenella sp. wzy002 360.0 360.0 1 PMID:24509923 -1.1.1.91 benzyl alcohol yokenella sp. wzy002 93.3 93.3 1 PMID:24509923 -1.1.1.91 cinnamaldehyde phanerodontia chrysosporium 11.17 11.17 1 PMID:29079624 -1.1.1.91 crotonaldehyde yokenella sp. wzy002 405.0 405.0 1 PMID:24509923 -1.1.1.91 crotonyl alcohol yokenella sp. wzy002 101.0 101.0 1 PMID:24509923 -1.1.1.91 heptanal phanerodontia chrysosporium 2.3 2.3 1 PMID:29079624 -1.1.1.91 heptanal saccharomyces cerevisiae 1.07 0.92 2 PMID:29079624 -1.1.1.91 hexanal phanerodontia chrysosporium 4.12 4.12 1 PMID:29079624 -1.1.1.91 hexanal saccharomyces cerevisiae 2.87 1.85 2 PMID:29079624 -1.1.1.91 nad+ ralstonia sp. 0.022 0.022 1 PMID:23686719 -1.1.1.91 nadh phanerodontia chrysosporium 2.0 2.0 1 PMID:22742413 -1.1.1.91 nadp+ phanerodontia chrysosporium 2.56 2.56 1 PMID:22742413 -1.1.1.91 nadp+ ralstonia sp. 1.65 1.65 1 PMID:23686719 -1.1.1.91 nadp+ yokenella sp. wzy002 433.0 313.5 2 PMID:24509923 -1.1.1.91 nadph phanerodontia chrysosporium 11.33 11.33 1 PMID:22742413 -1.1.1.91 phenylacetaldehyde phanerodontia chrysosporium 11.16 11.16 1 PMID:22742413 -1.1.1.91 trans-cinnamaldehyde phanerodontia chrysosporium 11.16 11.16 1 PMID:22742413 -1.1.1.93 d-malate pseudomonas putida 19.7 16.5 2 PMID:8053675 -1.1.1.93 isopropylmalate pseudomonas putida 0.2 0.1835 2 PMID:8053675 -1.1.1.93 l-tartrate pseudomonas putida 0.483 0.44999999999999996 2 PMID:8053675 -1.1.1.93 meso-tartrate pseudomonas putida 0.617 0.617 1 * -1.1.1.93 nad+ pseudomonas putida 6.5 6.5 1 PMID:20516620 -1.1.1.95 2-oxoglutarate arabidopsis thaliana 0.0002 0.00018 3 PMID:28615699 -1.1.1.95 2-oxoglutarate escherichia coli 12.0 7.05 2 PMID:30619878;PMID:31344342 -1.1.1.95 2-oxoglutarate homo sapiens 0.078 0.078 1 PMID:25406093 -1.1.1.95 3-phospho-d-glycerate arabidopsis thaliana 147.4 97.0 9 PMID:24368794;PMID:28615699 -1.1.1.95 3-phospho-d-glycerate bacillus subtilis 567.0 515.5 2 PMID:25698123 -1.1.1.95 3-phospho-d-glycerate corynebacterium glutamicum 350.0 274.0 2 PMID:25698123 -1.1.1.95 3-phospho-d-glycerate entamoeba histolytica 16.28 16.28 1 PMID:25294608 -1.1.1.95 3-phospho-d-glycerate escherichia coli 13.5 7.05 2 PMID:16363798;PMID:30619878 -1.1.1.95 3-phospho-d-glycerate homo sapiens 311.0 41.0 3 PMID:25406093;PMID:25698123 -1.1.1.95 3-phospho-d-glycerate marchantia polymorpha 25.0 25.0 1 PMID:30061906 -1.1.1.95 3-phospho-d-glycerate mycobacterium marinum 608.0 474.5 2 PMID:25698123 -1.1.1.95 3-phospho-d-glycerate mycobacterium tuberculosis 2425.0 1515.0 3 PMID:25698123;PMID:30619878 -1.1.1.95 3-phospho-d-glycerate mycolicibacterium smegmatis 3850.0 2712.5 2 PMID:25698123 -1.1.1.95 3-phospho-d-glycerate streptomyces coelicolor 576.0 385.0 2 PMID:25698123 -1.1.1.95 3-phosphohydroxypyruvate escherichia coli 0.463 0.463 1 PMID:8550422 -1.1.1.95 3-phosphohydroxypyruvate mycobacterium tuberculosis 2461.0 2461.0 1 PMID:17761677 -1.1.1.95 3-phosphooxypyruvate escherichia coli 8.0 5.55 2 PMID:30619878;PMID:31344342 -1.1.1.95 3-phosphooxypyruvate mycobacterium tuberculosis 2400.0 1503.0 2 PMID:30619878;PMID:31344342 -1.1.1.95 acetylpyridine homo sapiens 0.017 0.017 1 PMID:29262655 -1.1.1.95 alpha-ketoglutarate escherichia coli 0.555 0.3415 2 PMID:8550422;PMID:8798520 -1.1.1.95 d-2-hydroxyglutarate escherichia coli 0.7 0.7 1 PMID:30619878 -1.1.1.95 nad+ arabidopsis thaliana 147.4 97.0 9 PMID:24368794;PMID:28615699 -1.1.1.95 nad+ homo sapiens 0.005 0.005 1 PMID:29262655 -1.1.1.95 nad+ marchantia polymorpha 25.0 25.0 1 PMID:30061906 -1.1.1.95 nadh mycobacterium tuberculosis 2461.0 2461.0 1 PMID:18627175 -1.1.1.95 oxaloacetate arabidopsis thaliana 0.00135 0.00077 3 PMID:28615699 -1.1.1.95 oxaloacetate homo sapiens 0.177 0.177 1 PMID:25406093 -1.1.1.95 pyridinealdehyde adenine dinucleotide homo sapiens 0.0035 0.0035 1 PMID:29262655 -1.1.1.95 thionicotinamide homo sapiens 0.0075 0.0075 1 PMID:29262655 -1.1.2.10 cytochrome cgj methylorubrum extorquens 1.3 1.2 3 PMID:31017712 -1.1.2.10 methanol methylorubrum extorquens 4.0 2.8 6 PMID:31017712 -1.1.2.10 oxidized cytochrome cl methylorubrum extorquens 1.3 1.2 3 PMID:31017712 -1.1.2.3 (s)-lactate arabidopsis thaliana 14.18 14.18 1 PMID:26246447 -1.1.2.3 (s)-lactate saccharomyces cerevisiae 372.0 321.0 2 PMID:14690431;PMID:27220613 -1.1.2.3 cytochrome c saccharomyces cerevisiae 155.0 155.0 1 PMID:19821613 -1.1.2.3 fad saccharomyces cerevisiae 214.0 214.0 1 PMID:19821613 -1.1.2.3 ferricytochrome c saccharomyces cerevisiae 207.0 61.0 5 PMID:21503671;PMID:7626026 -1.1.2.3 fluoropyruvate saccharomyces cerevisiae 2.8 2.8 1 PMID:8142887 -1.1.2.3 l-lactate saccharomyces cerevisiae 473.0 138.5 22 PMID:10727218;PMID:17373777;PMID:17563122;PMID:7632684;PMID:8142887;PMID:9639570 -1.1.2.3 l-mandelate saccharomyces cerevisiae 0.02 0.02 1 PMID:9639570 -1.1.2.3 phenyllactate saccharomyces cerevisiae 16.5 16.5 1 * -1.1.2.4 (r)-lactate oryza sativa indica group 5.77 4.185 2 PMID:29259615 -1.1.2.4 d-2-hydroxybutyrate arabidopsis thaliana 1.467 1.467 1 PMID:19586914 -1.1.2.4 d-2-hydroxybutyrate oryza sativa indica group 10.03 9.805 2 PMID:29259615 -1.1.2.4 d-glycerate arabidopsis thaliana 0.1 0.1 1 PMID:19586914 -1.1.2.4 d-lactate arabidopsis thaliana 1.083 1.083 1 PMID:19586914 -1.1.2.4 d-lactate saccharomyces cerevisiae 1500.0 875.0 2 PMID:13729965;PMID:13950255 -1.1.2.4 glycolate arabidopsis thaliana 0.00167 0.00167 1 PMID:19586914 -1.1.2.4 l-lactate arabidopsis thaliana 0.1167 0.1167 1 PMID:19586914 -1.1.2.7 ferricytochrome cl hyphomicrobium denitrificans 0.87 0.37 6 PMID:16533029 -1.1.2.7 methanol hyphomicrobium denitrificans 0.87 0.87 1 PMID:16533029 -1.1.2.7 methanol methylophaga aminisulfidivorans 4.51 1.56 8 PMID:21656818 -1.1.2.8 ethanol pseudomonas putida 56.6 40.7 2 PMID:25229857 -1.1.2.8 propanol pseudomonas putida 73.1 52.849999999999994 2 PMID:25229857 -1.1.3.10 1,4-benzoquinone aspergillus nidulans 186.0 186.0 1 PMID:21968652 -1.1.3.10 1,4-benzoquinone aspergillus oryzae 3.04 3.04 1 PMID:21968652 -1.1.3.10 1,4-benzoquinone lyophyllum shimeji 92.3 92.3 1 PMID:20630076 -1.1.3.10 1,4-benzoquinone phanerodontia chrysosporium 477.0 438.5 2 PMID:19501263 -1.1.3.10 1,4-benzoquinone pseudarthrobacter siccitolerans 0.39 0.39 1 * -1.1.3.10 1,4-benzoquinone trametes ochracea 324.0 152.0 5 PMID:18495282;PMID:19143837;PMID:20528921 -1.1.3.10 1,5-anhydro-d-glucitol tricholoma matsutake 76.7 76.7 1 PMID:14730138 -1.1.3.10 2,2'-azinobis(3-ethylbenzthiazolinesulfonic acid) cation radical phanerodontia chrysosporium 1.33 1.33 1 PMID:19501263 -1.1.3.10 2,6-dichloroindophenol aspergillus nidulans 13.1 13.1 1 PMID:21968652 -1.1.3.10 2,6-dichloroindophenol lyophyllum shimeji 67.3 67.3 1 PMID:20630076 -1.1.3.10 2,6-dichloroindophenol phanerodontia chrysosporium 108.0 108.0 1 PMID:19501263 -1.1.3.10 2,6-dimethyl-1,4-benzoquinone aspergillus nidulans 0.4 0.4 1 PMID:21968652 -1.1.3.10 2,6-dimethyl-1,4-benzoquinone phanerodontia chrysosporium 8.69 8.69 1 PMID:19501263 -1.1.3.10 2-chloro-1,4-benzoquinone aspergillus nidulans 16.3 16.3 1 PMID:21968652 -1.1.3.10 2-chloro-1,4-benzoquinone phanerodontia chrysosporium 0.15 0.15 1 PMID:19501263 -1.1.3.10 2-methoxy-1,4-benzoquinone aspergillus nidulans 47.2 47.2 1 PMID:21968652 -1.1.3.10 2-methoxy-1,4-benzoquinone phanerodontia chrysosporium 40.1 40.1 1 PMID:19501263 -1.1.3.10 2-methyl-1,4-benzoquinone aspergillus nidulans 10.1 10.1 1 PMID:21968652 -1.1.3.10 2-methyl-1,4-benzoquinone phanerodontia chrysosporium 0.12 0.12 1 PMID:19501263 -1.1.3.10 cellobiose irpex lacteus 6.01 6.01 1 * -1.1.3.10 d-arabinose tricholoma matsutake 7.79 7.79 1 PMID:14730138 -1.1.3.10 d-fructose aspergillus nidulans 5.55 5.55 1 PMID:21968652 -1.1.3.10 d-fructose irpex lacteus 4.19 4.19 1 * -1.1.3.10 d-fructose phanerodontia chrysosporium 1.88 1.88 1 PMID:19501263 -1.1.3.10 d-galactose aspergillus nidulans 1.95 1.95 1 PMID:21968652 -1.1.3.10 d-galactose aspergillus oryzae 0.02 0.02 1 PMID:21968652 -1.1.3.10 d-galactose irpex lacteus 13.1 13.1 1 * -1.1.3.10 d-galactose lyophyllum shimeji 1.02 1.02 1 PMID:20630076 -1.1.3.10 d-galactose phanerodontia chrysosporium 4.87 4.87 1 PMID:19501263 -1.1.3.10 d-galactose pseudarthrobacter siccitolerans 0.57 0.57 1 * -1.1.3.10 d-galactose trametes ochracea 2.73 2.51 7 PMID:19143837;PMID:19370721;PMID:20089849;PMID:20158200;PMID:20528921;PMID:23578136;PMID:24466218 -1.1.3.10 d-galactose tricholoma matsutake 22.5 22.5 1 PMID:14730138 -1.1.3.10 d-glucono-1,5-lactone irpex lacteus 36.1 36.1 1 * -1.1.3.10 d-glucose aspergillus nidulans 35.44 35.44 1 PMID:21968652 -1.1.3.10 d-glucose aspergillus oryzae 1.48 1.48 1 PMID:21968652 -1.1.3.10 d-glucose irpex lacteus 33.8 33.8 1 * -1.1.3.10 d-glucose lyophyllum shimeji 6.92 6.92 1 PMID:20630076 -1.1.3.10 d-glucose phanerodontia chrysosporium 83.1 83.1 1 PMID:19501263 -1.1.3.10 d-glucose pseudarthrobacter siccitolerans 0.48 0.3165 2 * -1.1.3.10 d-glucose trametes ochracea 152.0 34.2 18 PMID:19143837;PMID:19317444;PMID:19370721;PMID:19595589;PMID:20089849;PMID:20158200;PMID:20528921;PMID:23578136;PMID:24466218;PMID:25296188;PMID:26828796 -1.1.3.10 d-glucose trametes sp. 6.1 6.1 1 PMID:29536215 -1.1.3.10 d-glucose tricholoma matsutake 111.0 111.0 1 PMID:14730138 -1.1.3.10 d-maltose tricholoma matsutake 62.9 62.9 1 PMID:14730138 -1.1.3.10 d-mannose irpex lacteus 6.2 6.2 1 * -1.1.3.10 d-mannose tricholoma matsutake 25.1 25.1 1 PMID:14730138 -1.1.3.10 d-melibiose trametes ochracea 7.6 7.6 1 PMID:20528921 -1.1.3.10 d-ribose pseudarthrobacter siccitolerans 0.38 0.38 1 * -1.1.3.10 d-xylose aspergillus nidulans 1.39 1.39 1 PMID:21968652 -1.1.3.10 d-xylose aspergillus oryzae 0.27 0.27 1 PMID:21968652 -1.1.3.10 d-xylose irpex lacteus 25.4 25.4 1 * -1.1.3.10 d-xylose lyophyllum shimeji 5.48 5.48 1 PMID:20630076 -1.1.3.10 d-xylose phanerodontia chrysosporium 44.9 44.9 1 PMID:19501263 -1.1.3.10 d-xylose pseudarthrobacter siccitolerans 0.91 0.91 1 * -1.1.3.10 d-xylose tricholoma matsutake 55.8 55.8 1 PMID:14730138 -1.1.3.10 ferricenium hexafluorophosphate aspergillus nidulans 158.0 158.0 1 PMID:21968652 -1.1.3.10 ferricenium hexafluorophosphate aspergillus oryzae 1.7 1.7 1 PMID:21968652 -1.1.3.10 ferricenium hexafluorophosphate phanerodontia chrysosporium 549.0 388.5 2 PMID:19501263 -1.1.3.10 ferricenium ion trametes ochracea 151.0 78.17 2 PMID:19143837 -1.1.3.10 ferricyanide phanerodontia chrysosporium 0.3 0.3 1 PMID:19501263 -1.1.3.10 ferrocenium hexafluorophosphate trametes ochracea 210.0 108.3 2 PMID:20528921 -1.1.3.10 ferrocenium ion lyophyllum shimeji 39.9 39.9 1 PMID:20630076 -1.1.3.10 glucose trametes ochracea 49.0 49.0 1 PMID:18495282 -1.1.3.10 l-arabinose pseudarthrobacter siccitolerans 0.19 0.19 1 * -1.1.3.10 l-sorbose aspergillus nidulans 9.66 9.66 1 PMID:21968652 -1.1.3.10 l-sorbose aspergillus oryzae 1.59 1.59 1 PMID:21968652 -1.1.3.10 l-sorbose irpex lacteus 41.4 41.4 1 * -1.1.3.10 l-sorbose lyophyllum shimeji 7.7 7.7 1 PMID:20630076 -1.1.3.10 l-sorbose phanerodontia chrysosporium 58.8 58.8 1 PMID:19501263 -1.1.3.10 l-sorbose tricholoma matsutake 74.6 74.6 1 PMID:14730138 -1.1.3.10 maltose irpex lacteus 31.1 31.1 1 * -1.1.3.10 melibiose lyophyllum shimeji 0.839 0.839 1 PMID:20630076 -1.1.3.10 o2 phanerodontia chrysosporium 109.0 109.0 1 PMID:19501263 -1.1.3.10 o2 trametes ochracea 70.0 6.8 5 PMID:18495282;PMID:19146821 -1.1.3.10 sucrose irpex lacteus 27.9 27.9 1 * -1.1.3.10 tetrafluoro-1,4-benzoquinone aspergillus nidulans 129.0 129.0 1 PMID:21968652 -1.1.3.10 tetrafluoro-1,4-benzoquinone phanerodontia chrysosporium 6.61 6.61 1 PMID:19501263 -1.1.3.10 trehalose tricholoma matsutake 59.6 59.6 1 PMID:14730138 -1.1.3.12 pyridoxine mesorhizobium loti 19.9 19.9 1 PMID:23501672 -1.1.3.13 (r)-1,2-propanediol phanerodontia chrysosporium 5.0 5.0 1 PMID:30272958 -1.1.3.13 1-decanol colletotrichum graminicola 87.5 87.5 1 * -1.1.3.13 1-heptanol colletotrichum graminicola 85.8 85.8 1 * -1.1.3.13 1-hexanol arthrobacter globiformis 0.047 0.047 1 PMID:30338899 -1.1.3.13 1-octanol colletotrichum graminicola 84.4 84.4 1 * -1.1.3.13 1-propanol ogataea thermomethanolica (nom. inval.) 93.83 93.83 1 PMID:29738827 -1.1.3.13 1-propanol phanerodontia chrysosporium 11.0 11.0 1 PMID:30272958 -1.1.3.13 2,2'-sulfanediyldi(ethan-1-ol) phanerodontia chrysosporium 3.56 3.56 1 PMID:31912947 -1.1.3.13 butane-1,4-diol phanerodontia chrysosporium 6.74 6.74 1 PMID:31912947 -1.1.3.13 cyclohexanol levilactobacillus brevis 2.2 2.1 2 PMID:30184296 -1.1.3.13 cyclohexanol thermoanaerobacter brockii 8.3 7.0 2 PMID:30184296 -1.1.3.13 diethylene glycol phanerodontia chrysosporium 0.73 0.73 1 PMID:31912947 -1.1.3.13 ethanol ogataea angusta 58.0 58.0 1 PMID:16545060 -1.1.3.13 ethanol ogataea thermomethanolica (nom. inval.) 103.9 103.9 1 PMID:29738827 -1.1.3.13 ethanol phanerodontia chrysosporium 19.0 19.0 1 PMID:30272958 -1.1.3.13 formaldehyde ogataea angusta 32.0 32.0 1 PMID:16545060 -1.1.3.13 hexan-1-ol phanerodontia chrysosporium 0.56 0.56 1 PMID:31912947 -1.1.3.13 hexane-1,6-diol phanerodontia chrysosporium 4.07 4.07 1 PMID:31912947 -1.1.3.13 methanol gloeophyllum trabeum 15.6 15.6 1 PMID:17660304 -1.1.3.13 methanol komagataella pastoris 5.72 5.72 1 PMID:26905908 -1.1.3.13 methanol ogataea angusta 60.0 60.0 1 PMID:16545060 -1.1.3.13 methanol ogataea thermomethanolica (nom. inval.) 60.48 60.48 1 PMID:29738827 -1.1.3.13 methanol phanerodontia chrysosporium 18.0 18.0 1 PMID:30272958 -1.1.3.13 n-heptanol aspergillus terreus 270.0 270.0 1 PMID:18639656 -1.1.3.13 pentane-1,4-diol phanerodontia chrysosporium 1.28 1.28 1 PMID:31912947 -1.1.3.13 pentane-1,5-diol phanerodontia chrysosporium 3.48 3.48 1 PMID:31912947 -1.1.3.15 2-oxo-octanoate homo sapiens 0.08 0.08 1 PMID:18215067 -1.1.3.15 bromopyruvate rattus sp. 0.36 0.36 1 PMID:3061453 -1.1.3.15 dl-2-hydroxy-4-methylthiobutanoic acid rattus sp. 2.1 2.0 2 PMID:8706682 -1.1.3.15 dl-2-hydroxybutyrate rattus sp. 2.0 1.66 3 PMID:8706682 -1.1.3.15 flavin homo sapiens 54.1 54.1 1 PMID:19758989 -1.1.3.15 glycerate spinacia oleracea 1.04 1.04 1 PMID:16622317 -1.1.3.15 glycolate homo sapiens 31.2 15.649999999999999 6 PMID:17669354;PMID:18215067;PMID:19758989 -1.1.3.15 glycolate mycolicibacterium smegmatis 0.33 0.33 1 PMID:7358709 -1.1.3.15 glycolate ricinus communis 1.0 1.0 1 PMID:33170407 -1.1.3.15 glyoxylate homo sapiens 0.83 0.7649999999999999 2 PMID:17669354;PMID:18215067 -1.1.3.15 l-2-hydroxy octanoate rattus norvegicus 0.99 0.99 1 PMID:15683236 -1.1.3.15 l-2-hydroxy palmitate rattus norvegicus 0.34 0.34 1 PMID:15683236 -1.1.3.15 l-2-hydroxy-4-methylthiobutanoic acid gallus gallus 0.74 0.74 1 PMID:9924984 -1.1.3.15 l-2-hydroxyisocaproate rattus sp. 2.4 2.2 2 PMID:8706682 -1.1.3.15 l-lactate aerococcus viridans 4.7 2.6100000000000003 2 PMID:8589073 -1.1.3.15 l-lactate homo sapiens 0.46 0.46 1 PMID:17669354 -1.1.3.15 l-lactate rattus sp. 0.433 0.38 3 PMID:5946631;PMID:8706682 -1.1.3.15 l-leucine rattus sp. 0.014 0.014 1 PMID:8706682 -1.1.3.15 l-mandelate homo sapiens 0.11 0.11 1 PMID:17669354 -1.1.3.15 l-mandelate rattus sp. 2.51 2.03 2 PMID:8706682 -1.1.3.15 l-phenyllactate rattus sp. 0.7 0.645 2 PMID:8706682 -1.1.3.15 o2 aerococcus viridans 4.7 2.6100000000000003 2 PMID:8589073 -1.1.3.15 o2 mycolicibacterium smegmatis 1.1 1.1 1 PMID:7358709 -1.1.3.17 3,3-dimethyl-1-butanol arthrobacter globiformis 8.0 8.0 1 PMID:15369826 -1.1.3.17 betaine aldehyde arthrobacter globiformis 133.0 133.0 3 PMID:15713082;PMID:20561507;PMID:29029877 -1.1.3.17 betaine-aldehyde arthrobacter globiformis 11.6 6.654999999999999 2 PMID:12637017;PMID:14678796 -1.1.3.17 choline alcaligenes sp. 3.0 2.915 2 * -1.1.3.17 choline arthrobacter globiformis 86.0 14.9 13 PMID:12637017;PMID:14678796;PMID:15369826;PMID:15654745;PMID:15713082;PMID:17143885;PMID:20163155;PMID:20561507;PMID:26907558;PMID:30338899 -1.1.3.17 n,n-dimethylethanolamine arthrobacter globiformis 5.9 5.9 1 PMID:15369826 -1.1.3.17 n-methylethanolamine arthrobacter globiformis 0.37 0.37 1 PMID:15369826 -1.1.3.17 o2 arthrobacter globiformis 15.0 15.0 1 PMID:25478900 -1.1.3.2 (s)-lactate aerococcus viridans 280.0 88.0 5 PMID:25423902;PMID:26260739;PMID:27302031;PMID:8589073 -1.1.3.2 (s)-mandelic acid aerococcus viridans 0.0033 0.0033 1 PMID:8910450 -1.1.3.2 2-hydroxybutanoate aerococcus viridans 11.0 11.0 1 PMID:8910450 -1.1.3.2 2-hydroxypentanoate aerococcus viridans 1.25 1.25 1 PMID:8910450 -1.1.3.2 glycerate aerococcus viridans 0.87 0.87 1 PMID:8910450 -1.1.3.2 l-lactate aerococcus viridans 283.0 283.0 1 PMID:8910450 -1.1.3.21 sn-glycerol 3-phosphate enterococcus faecium 23.8 23.8 1 PMID:3771536 -1.1.3.21 sn-glycerol 3-phosphate streptococcus sp. 17.9 16.0 2 PMID:18154320 -1.1.3.23 h2o2 unidentified soil bacterium 5.0 5.0 1 PMID:2988447 -1.1.3.23 thiamine unidentified soil bacterium 1.67 1.67 1 PMID:4987737 -1.1.3.30 polyvinyl alcohol stenotrophomonas rhizophila 45.3 45.0 2 PMID:29079625 -1.1.3.37 d-arabinono-1,4-lactone candida albicans 20.9 20.9 1 PMID:8841374 -1.1.3.37 d-arabinono-1,4-lactone leishmania donovani 10.8 10.8 1 PMID:21907739 -1.1.3.37 l-galactono-1,4-lactone candida albicans 18.3 18.3 1 PMID:8841374 -1.1.3.38 (r)-1-(4'-hydroxyphenol)ethanol penicillium simplicissimum 0.7 0.7 1 PMID:8529652 -1.1.3.38 (r,s)-1-(4'-hydroxyphenyl)propanol penicillium simplicissimum 3.0 3.0 1 PMID:9791114 -1.1.3.38 (s)-1-(4'-hydroxyphenyl)ethanol penicillium simplicissimum 4.4 4.4 1 PMID:9791114 -1.1.3.38 1-(4'-hydroxyphenyl)-2-butanone penicillium simplicissimum 0.3 0.3 1 PMID:9791114 -1.1.3.38 2-(4'-hydroxyphenyl)ethanol penicillium simplicissimum 0.004 0.004 1 PMID:9791114 -1.1.3.38 2-amino-p-cresol penicillium simplicissimum 0.017 0.009000000000000001 2 PMID:15169773 -1.1.3.38 2-methoxy-4-n-propylphenol penicillium simplicissimum 3.2 3.2 1 PMID:9791114 -1.1.3.38 2-methoxy-4-propylphenol penicillium simplicissimum 4.8 4.8 1 PMID:10099328 -1.1.3.38 2-methyl-p-cresol penicillium simplicissimum 0.031 0.0165 2 PMID:15169773 -1.1.3.38 3-(4'-hydroxyphenol)propanol penicillium simplicissimum 0.1 0.1 1 PMID:9791114 -1.1.3.38 4-(3'-methylcrotyl)phenol penicillium simplicissimum 1.4 1.4 1 PMID:9791114 -1.1.3.38 4-(methoxymethyl)-phenol penicillium simplicissimum 5.3 5.3 1 PMID:8529652 -1.1.3.38 4-(methoxymethyl)phenol penicillium simplicissimum 3.9 3.1 3 PMID:10920192;PMID:15169773 -1.1.3.38 4-(methoxymethyl)phenol rhodococcus jostii 0.004 0.004 1 PMID:17419730 -1.1.3.38 4-cyclopentylphenol penicillium simplicissimum 3.7 3.7 1 PMID:29342886 -1.1.3.38 4-ethylguaiacol rhodococcus jostii 0.026 0.026 1 PMID:17419730 -1.1.3.38 4-ethylphenol penicillium simplicissimum 2.7 2.6 3 PMID:10099328;PMID:27214042;PMID:9654070;PMID:9791114 -1.1.3.38 4-hydroxy-3-methoxybenzylamine penicillium simplicissimum 1.3 1.3 1 PMID:8529652 -1.1.3.38 4-hydroxy-3-methoxyphenylglycol penicillium simplicissimum 3.6 3.6 1 PMID:8529652 -1.1.3.38 4-isopropylphenol penicillium simplicissimum 1.3 1.3 1 PMID:9791114 -1.1.3.38 4-methylphenol penicillium simplicissimum 0.005 0.005 1 PMID:9654070 -1.1.3.38 4-n-butylphenol penicillium simplicissimum 1.2 1.2 1 PMID:9791114 -1.1.3.38 4-n-pentylphenol penicillium simplicissimum 0.3 0.3 1 PMID:8529652;PMID:9791114 -1.1.3.38 4-n-propylphenol penicillium simplicissimum 4.2 4.2 1 PMID:9654070;PMID:9791114 -1.1.3.38 4-propylphenol penicillium simplicissimum 3.9 3.9 1 PMID:10099328 -1.1.3.38 4-sec-butylphenol penicillium simplicissimum 0.5 0.5 1 PMID:9791114 -1.1.3.38 5,6,7,8-tetrahydro-2-naphthol penicillium simplicissimum 0.7 0.7 1 PMID:9791114 -1.1.3.38 5-indanol penicillium simplicissimum 0.5 0.5 1 PMID:9791114 -1.1.3.38 chavicol penicillium simplicissimum 7.4 6.95 2 PMID:28717004;PMID:8529652 -1.1.3.38 creosol penicillium simplicissimum 0.07 0.013 5 PMID:11409992;PMID:15169773 -1.1.3.38 eugenol penicillium simplicissimum 39.0 13.5 4 PMID:15169773;PMID:27214042;PMID:9791114 -1.1.3.38 metanephrine penicillium simplicissimum 0.8 0.8 1 PMID:8529652 -1.1.3.38 norepinephrine penicillium simplicissimum 0.3 0.3 1 PMID:8529652 -1.1.3.38 normetanephrine penicillium simplicissimum 0.7 0.7 1 PMID:8529652 -1.1.3.38 vanillyl alcohol methylovorus sp. mp688 19.5 19.5 1 PMID:32503910 -1.1.3.38 vanillyl alcohol penicillium simplicissimum 5.4 2.55 6 PMID:15169773;PMID:27214042;PMID:28717004;PMID:29342886;PMID:8529652 -1.1.3.38 vanillyl alcohol pseudomonas sp. 11/12a 8.0 8.0 1 PMID:32503910 -1.1.3.38 vanillyl alcohol rhodococcus jostii 12.0 12.0 1 PMID:17419730 -1.1.3.38 vanillylamine penicillium simplicissimum 0.02 0.02 1 PMID:11409992 -1.1.3.38 vanillylamine rhodococcus jostii 0.26 0.26 1 PMID:17419730 -1.1.3.4 (r)-1-phenyl-1,2-ethanediol streptomyces coelicolor 0.74 0.74 1 * -1.1.3.4 (s)-1-phenyl-1,2-ethanediol streptomyces coelicolor 0.008 0.008 1 * -1.1.3.4 1,2,4-butanetriol streptomyces coelicolor 4.4 4.4 1 * -1.1.3.4 1,2-butanediol streptomyces coelicolor 0.29 0.29 1 * -1.1.3.4 1,2-hexanediol streptomyces coelicolor 2.0 2.0 1 * -1.1.3.4 1,2-pentanediol streptomyces coelicolor 0.85 0.85 1 * -1.1.3.4 1-phenyl-1,2-ethanediol streptomyces coelicolor 0.36 0.36 1 * -1.1.3.4 2,6-dichloroindophenol pleurotus ostreatus 1.13 1.13 1 PMID:8354282 -1.1.3.4 2-amino-1-pentanol streptomyces coelicolor 0.017 0.017 1 * -1.1.3.4 3-butene-1,2-diol streptomyces coelicolor 0.34 0.34 1 * -1.1.3.4 3-butenol streptomyces coelicolor 0.1 0.1 1 * -1.1.3.4 4-benzoquinone pleurotus ostreatus 15.5 15.5 1 PMID:8354282 -1.1.3.4 4-pentene-1,2-diol streptomyces coelicolor 0.35 0.35 1 * -1.1.3.4 [(1,10-phenanthroline)2(cl)2ru(iii)] aspergillus niger 10.5 10.5 1 PMID:12765523 -1.1.3.4 [(1,8-dimethyl-4,5-phenanthroline)3ru(ii)]pf6- aspergillus niger 50.3 50.3 1 PMID:12765523 -1.1.3.4 [(2,2'-(4,4'dimethyl)bipyridine)2(cl)2ru(iii)] aspergillus niger 10.5 10.5 1 PMID:12765523 -1.1.3.4 [(2,2'-(4,4'dimethyl)bipyridine)2(cl)2ru(iii)]pf6- aspergillus niger 13.8 13.8 1 PMID:12765523 -1.1.3.4 [(2,2'-bipyridine)2(co32-)1/2ru(iii)] aspergillus niger 38.6 38.6 1 PMID:12765523 -1.1.3.4 [(2,2'-bipyridine)2(h2o)2ru(iii)]pf6- aspergillus niger 8.3 8.3 1 PMID:12765523 -1.1.3.4 [(2,2'-bipyridine)2(scn-)2ru(iii)] aspergillus niger 31.4 31.4 1 PMID:12765523 -1.1.3.4 [(2,2'-bipyridine)3ru(ii)]pf6- aspergillus niger 158.0 158.0 1 PMID:12765523 -1.1.3.4 beta-d-glucose aspergillus niger 1938.0 56.4 28 PMID:12093294;PMID:182278;PMID:1932088;PMID:19784554;PMID:21040747;PMID:21915588;PMID:22050076;PMID:22900328;PMID:23562736;PMID:24122283;PMID:25061935;PMID:27641970;PMID:29291138 -1.1.3.4 beta-d-glucose aspergillus tubingensis 602.51 602.51 1 PMID:26280215 -1.1.3.4 beta-d-glucose cladosporium neopsychrotolerans 97.0 97.0 1 PMID:31838375 -1.1.3.4 beta-d-glucose goffeauzyma gastrica 2300.0 2300.0 1 PMID:29312954 -1.1.3.4 beta-d-glucose penicillium amagasakiense 2003.0 1879.0 8 PMID:10749686;PMID:21040747;PMID:9546178 -1.1.3.4 beta-d-glucose penicillium sp. 741.0 741.0 1 PMID:17084642 -1.1.3.4 beta-d-glucose penicillium sp. mx3343 137.1 137.1 1 PMID:33329498 -1.1.3.4 d-glucose penicillium adametzii 318.2 235.1 3 * -1.1.3.4 d-mannitol streptomyces coelicolor 9.2 9.2 1 * -1.1.3.4 d-sorbitol streptomyces coelicolor 17.0 17.0 1 * -1.1.3.4 di-(2,2'-bipyridinyl)ruthenium(iii)dichloride aspergillus niger 35.4 35.4 1 PMID:12765523 -1.1.3.4 glycerol streptomyces coelicolor 1.6 1.6 1 * -1.1.3.4 l-arabinose streptomyces coelicolor 1.7 1.7 1 * -1.1.3.4 l-threitol streptomyces coelicolor 6.3 6.3 1 * -1.1.3.4 n,n,n',n'-tetramethyl-1,4-phenylenediamine pleurotus ostreatus 0.33 0.33 1 PMID:8354282 -1.1.3.4 xylitol streptomyces coelicolor 13.0 13.0 1 * -1.1.3.41 (r)-1-phenyl-1,2-ethanediol acidothermus cellulolyticus 0.1 0.1 1 PMID:22231860 -1.1.3.41 (r)-1-phenyl-1,2-ethanediol streptomyces coelicolor 0.74 0.74 3 PMID:22231860 -1.1.3.41 (s)-1-phenyl-1,2-ethanediol acidothermus cellulolyticus 0.0004 0.0004 1 PMID:22231860 -1.1.3.41 (s)-1-phenyl-1,2-ethanediol streptomyces coelicolor 0.008 0.008 3 PMID:22231860 -1.1.3.41 1,2,4-butanetriol streptomyces coelicolor 4.4 4.4 2 * -1.1.3.41 1,2-butanediol streptomyces coelicolor 0.29 0.29 2 * -1.1.3.41 1,2-hexanediol streptomyces coelicolor 2.0 2.0 2 * -1.1.3.41 1,2-pentanediol streptomyces coelicolor 0.85 0.85 2 * -1.1.3.41 1-phenyl-1,2-ethanediol acidothermus cellulolyticus 0.1 0.1 1 PMID:22231860 -1.1.3.41 1-phenyl-1,2-ethanediol streptomyces coelicolor 0.36 0.36 3 PMID:22231860 -1.1.3.41 2-amino-1-pentanol streptomyces coelicolor 0.017 0.017 2 * -1.1.3.41 3-butene-1,2-diol streptomyces coelicolor 0.34 0.34 2 * -1.1.3.41 3-butenol streptomyces coelicolor 0.1 0.1 2 * -1.1.3.41 4-pentene-1,2-diol streptomyces coelicolor 0.35 0.35 2 * -1.1.3.41 d-mannitol acidothermus cellulolyticus 2.5 2.5 1 PMID:22231860 -1.1.3.41 d-mannitol streptomyces coelicolor 9.2 9.2 3 PMID:22231860 -1.1.3.41 d-sorbitol acidothermus cellulolyticus 1.2 1.2 1 PMID:22231860 -1.1.3.41 d-sorbitol streptomyces coelicolor 17.0 17.0 3 PMID:22231860 -1.1.3.41 glycerol acidothermus cellulolyticus 1.3 1.3 1 PMID:22231860 -1.1.3.41 glycerol streptomyces coelicolor 1.6 1.6 3 PMID:22231860 -1.1.3.41 l-arabinose streptomyces coelicolor 1.7 1.7 2 * -1.1.3.41 l-threitol streptomyces coelicolor 6.3 6.3 2 * -1.1.3.41 xylitol acidothermus cellulolyticus 1.9 1.9 1 PMID:22231860 -1.1.3.41 xylitol streptomyces coelicolor 13.0 13.0 3 PMID:22231860 -1.1.3.46 (s)-4-hydroxymandelate streptomyces coelicolor 3.5 3.5 1 PMID:25713978 -1.1.3.46 (s)-mandelate amycolatopsis orientalis 5.17 5.17 1 PMID:31373572 -1.1.3.46 l-mandelate streptomyces coelicolor 1.2 1.2 1 PMID:25713978 -1.1.3.47 2,5-diformylfuran fusarium graminearum 3.6 3.6 1 PMID:34134727 -1.1.3.47 2,5-diformylfuran fusarium oxysporum f. sp. lycopersici 1.4 1.4 1 PMID:34134727 -1.1.3.47 2,5-diformylfuran pleurotus eryngii 31.4 31.4 1 PMID:25639975 -1.1.3.47 3-methoxybenzyl alcohol fusarium graminearum 52.0 52.0 1 PMID:34134727 -1.1.3.47 3-methoxybenzyl alcohol fusarium oxysporum f. sp. lycopersici 34.0 34.0 1 PMID:34134727 -1.1.3.47 4-(hydroxymethyl)benzaldehyde methylovorus sp. mp688 8.6 8.6 1 PMID:24802551 -1.1.3.47 4-anisaldehyde pleurotus eryngii 0.12 0.11 3 PMID:31528205 -1.1.3.47 4-hydroxy-3-methoxybenzyl alcohol methylovorus sp. mp688 21.0 21.0 1 * -1.1.3.47 4-methoxybenzyl alcohol fusarium graminearum 32.0 32.0 1 PMID:34134727 -1.1.3.47 4-methoxybenzyl alcohol fusarium oxysporum f. sp. lycopersici 34.0 34.0 1 PMID:34134727 -1.1.3.47 4-methoxybenzyl alcohol pleurotus eryngii 108.0 97.0 5 PMID:31528205 -1.1.3.47 5-(hydroxymethyl)furan-2-carboxylic acid colletotrichum graminicola 28.3 28.3 1 * -1.1.3.47 5-(hydroxymethyl)furan-2-carboxylic acid fusarium graminearum 3.8 3.8 1 PMID:34134727 -1.1.3.47 5-(hydroxymethyl)furan-2-carboxylic acid fusarium oxysporum f. sp. lycopersici 5.2 5.2 1 PMID:34134727 -1.1.3.47 5-(hydroxymethyl)furfural methylovorus sp. mp688 13.7 9.9 4 PMID:24271187;PMID:24802551;PMID:29507608;PMID:32503910 -1.1.3.47 5-(hydroxymethyl)furfural pseudomonas nitroreducens 0.24 0.24 1 PMID:32503910 -1.1.3.47 5-(hydroxymethyl)furfural pseudomonas sp. 11/12a 1.0 1.0 1 PMID:32503910 -1.1.3.47 5-(hydroxymethyl)furfural trametes cinnabarina 0.75 0.655 2 PMID:30984409 -1.1.3.47 5-formyl-2-furan carboxylic acid trametes cinnabarina 2.0 1.02 2 PMID:30984409 -1.1.3.47 5-formylfuran-2-carboxylate pseudomonas nitroreducens 0.008 0.008 1 PMID:32503910 -1.1.3.47 5-formylfuran-2-carboxylate pseudomonas sp. 11/12a 0.002 0.002 1 PMID:32503910 -1.1.3.47 5-hydroxymethylfurfural colletotrichum graminicola 126.0 126.0 1 * -1.1.3.47 5-hydroxymethylfurfural fusarium graminearum 29.0 29.0 1 PMID:34134727 -1.1.3.47 5-hydroxymethylfurfural fusarium oxysporum f. sp. lycopersici 26.0 26.0 1 PMID:34134727 -1.1.3.47 5-hydroxymethylfurfural pleurotus eryngii 20.1 10.385000000000002 2 PMID:25639975;PMID:31676448 -1.1.3.47 benzyl alcohol fusarium graminearum 37.0 37.0 1 PMID:34134727 -1.1.3.47 benzyl alcohol fusarium oxysporum f. sp. lycopersici 31.0 31.0 1 PMID:34134727 -1.1.3.47 furan-2,5-dicarbaldehyde methylovorus sp. mp688 1.6 0.8500000000000001 2 PMID:24802551;PMID:32503910 -1.1.3.47 furan-2,5-dicarbaldehyde pseudomonas nitroreducens 0.017 0.017 1 PMID:32503910 -1.1.3.47 furan-2,5-dicarbaldehyde pseudomonas sp. 11/12a 0.01 0.01 1 PMID:32503910 -1.1.3.47 furan-2,5-dicarbaldehyde trametes cinnabarina 4.8 3.04 2 PMID:30984409 -1.1.3.47 terephthaldehyde methylovorus sp. mp688 1.3 1.3 1 PMID:24802551 -1.1.3.47 vanillyl alcohol pseudomonas nitroreducens 1.0 1.0 1 PMID:32503910 -1.1.3.47 veratryl alcohol fusarium graminearum 41.0 41.0 1 PMID:34134727 -1.1.3.47 veratryl alcohol fusarium oxysporum f. sp. lycopersici 25.0 25.0 1 PMID:34134727 -1.1.3.50 carminate microbacterium sp. 5-2b 4.3 4.3 1 PMID:34583991 -1.1.3.6 3beta-hydroxy-5-androsten-17-one brevibacterium sterolicum 0.8 0.8 2 PMID:10447682;PMID:9428686 -1.1.3.6 3beta-hydroxy-androst-5-en-17-one brevibacterium sterolicum 0.8 0.8 1 PMID:10447682 -1.1.3.6 3beta-hydroxy-androst-5-en-17-one streptomyces hygroscopicus 8.2 8.2 3 PMID:10447682;PMID:9428686 -1.1.3.6 5-cholesten-3-one brevibacterium sterolicum 278.0 264.0 2 PMID:10447682;PMID:9428686 -1.1.3.6 5-cholesten-3-one streptomyces hygroscopicus 670.0 332.0 3 PMID:10447682;PMID:9428686 -1.1.3.6 beta-sitosterol pimelobacter simplex 9.86 9.86 1 PMID:29180806 -1.1.3.6 cholestanol brevibacterium sterolicum 40.0 40.0 3 PMID:10447682;PMID:19843169;PMID:9428686 -1.1.3.6 cholestanol streptomyces hygroscopicus 37.0 37.0 3 PMID:10447682;PMID:19843169;PMID:9428686 -1.1.3.6 cholesterol brevibacterium sterolicum 105.0 48.1 11 PMID:10447682;PMID:19843169;PMID:9428686 -1.1.3.6 cholesterol castellaniella sp. 10.6 10.6 1 PMID:31750957 -1.1.3.6 cholesterol pimelobacter simplex 12.29 12.29 1 PMID:29180806 -1.1.3.6 cholesterol rhodococcus erythropolis 6.8 3.705 2 PMID:33104755 -1.1.3.6 cholesterol streptomyces hygroscopicus 345.0 19.5 10 PMID:10447682;PMID:19843169;PMID:9428686 -1.1.3.6 cholesterol streptomyces sp. 47.3 45.0 8 PMID:10194345;PMID:12051668;PMID:12082166;PMID:18410129;PMID:19923719 -1.1.3.6 cholesterol streptomyces sp. sa-coo 67.0 67.0 1 PMID:30125103 -1.1.3.6 dehydroepiandrosterone pimelobacter simplex 6.82 6.82 1 PMID:29180806 -1.1.3.6 dehydroepiandrosterone streptomyces sp. 0.69 0.69 1 PMID:10194345 -1.1.3.6 epiandrosterone streptomyces hygroscopicus 7.0 7.0 1 PMID:10447682 -1.1.3.6 pregnenolone brevibacterium sterolicum 35.0 21.0 4 PMID:10447682;PMID:19843169;PMID:9428686 -1.1.3.6 pregnenolone pimelobacter simplex 11.78 11.78 1 PMID:29180806 -1.1.3.6 pregnenolone streptomyces hygroscopicus 24.0 24.0 4 PMID:10447682;PMID:19843169;PMID:9428686 -1.1.3.6 pregnenolone streptomyces sp. 30.0 30.0 1 PMID:12082166 -1.1.3.6 stigmasterol pimelobacter simplex 1.58 1.58 1 PMID:29180806 -1.1.3.6 trans-androsterone brevibacterium sterolicum 0.8 0.8 1 PMID:19843169 -1.1.3.6 trans-androsterone streptomyces hygroscopicus 7.0 7.0 1 PMID:19843169 -1.1.3.6 trans-dehydroandrosterone brevibacterium sterolicum 1.0 0.9 2 PMID:19843169 -1.1.3.6 trans-dehydroandrosterone streptomyces hygroscopicus 8.2 7.1 2 PMID:19843169 -1.1.3.7 (2e,4e)-hexa-2,4-dien-1-ol coprinopsis cinerea 48.3 48.3 1 PMID:29785669 -1.1.3.7 (r,s)-4-methoxybenzyl alcohol komagataella pastoris 44.0 32.0 6 * -1.1.3.7 2,4-dimethoxybenzyl alcohol mycosarcoma maydis 30.0 30.0 1 PMID:26452496 -1.1.3.7 2,4-hexadien-1-ol mycosarcoma maydis 64.0 64.0 1 PMID:26452496 -1.1.3.7 2,4-hexadien-1-ol pleurotus eryngii 161.0 119.0 7 PMID:15813702;PMID:16999821;PMID:19574215;PMID:26162870;PMID:29532900 -1.1.3.7 2,4-hexadienal pleurotus eryngii 0.33 0.33 1 PMID:19891608 -1.1.3.7 2,5-diformylfuran fusarium graminearum 3.6 3.6 1 PMID:34134727 -1.1.3.7 2,5-diformylfuran fusarium oxysporum f. sp. lycopersici 1.4 1.4 1 PMID:34134727 -1.1.3.7 2,5-diformylfuran pleurotus eryngii 31.4 31.4 1 PMID:25639975 -1.1.3.7 3,4-difluorobenzaldehyde pleurotus eryngii 0.867 0.867 1 PMID:19891608 -1.1.3.7 3,4-dimethoxybenzyl alcohol aspergillus terreus 105.7 105.7 1 PMID:24752075 -1.1.3.7 3,4-dimethoxybenzyl alcohol lentinus sajor-caju 82.2 73.25 2 PMID:3060110 -1.1.3.7 3,4-dimethoxybenzyl alcohol pleurotus pulmonarius 30.0 30.0 1 PMID:10606774 -1.1.3.7 3-anisyl alcohol colletotrichum graminicola 140.0 140.0 1 * -1.1.3.7 3-anisyl alcohol coprinopsis cinerea 7.66 7.66 1 PMID:29785669 -1.1.3.7 3-anisyl alcohol pleurotus eryngii 15.0 15.0 2 PMID:15813702;PMID:16999821 -1.1.3.7 3-chloro-4-anisaldehyde pleurotus eryngii 0.057 0.057 1 PMID:19891608 -1.1.3.7 3-chloro-4-anisyl alcohol pleurotus eryngii 46.0 46.0 1 PMID:15813702 -1.1.3.7 3-chlorobenzaldehyde pleurotus eryngii 0.85 0.85 1 PMID:19891608 -1.1.3.7 3-chlorobenzyl alcohol pleurotus eryngii 22.0 22.0 1 PMID:15813702 -1.1.3.7 3-fluorobenzaldehyde pleurotus eryngii 0.883 0.883 1 PMID:19891608 -1.1.3.7 3-fluorobenzyl alcohol pleurotus eryngii 6.0 6.0 1 PMID:15813702 -1.1.3.7 3-hydroxybenzyl alcohol coprinopsis cinerea 9.91 9.91 1 PMID:29785669 -1.1.3.7 3-methoxybenzyl alcohol aspergillus terreus 115.4 115.4 1 PMID:24752075 -1.1.3.7 3-methoxybenzyl alcohol fusarium graminearum 52.0 52.0 1 PMID:34134727 -1.1.3.7 3-methoxybenzyl alcohol fusarium oxysporum f. sp. lycopersici 34.0 34.0 1 PMID:34134727 -1.1.3.7 4-anisaldehyde pleurotus eryngii 0.12 0.11 4 PMID:19891608;PMID:31528205 -1.1.3.7 4-anisyl alcohol colletotrichum graminicola 48.0 48.0 1 * -1.1.3.7 4-anisyl alcohol coprinopsis cinerea 12.5 12.5 1 PMID:29785669 -1.1.3.7 4-anisyl alcohol pleurotus eryngii 142.0 142.0 3 PMID:15813702;PMID:16999821;PMID:19574215 -1.1.3.7 4-chlorobenzaldehyde pleurotus eryngii 1.05 1.05 1 PMID:19891608 -1.1.3.7 4-chlorobenzyl alcohol pleurotus eryngii 51.0 51.0 1 PMID:15813702 -1.1.3.7 4-fluorobenzaldehyde pleurotus eryngii 0.367 0.367 1 PMID:19891608 -1.1.3.7 4-fluorobenzyl alcohol pleurotus eryngii 32.0 32.0 1 PMID:15813702 -1.1.3.7 4-hydroxybenzyl alcohol colletotrichum graminicola 20.1 20.1 1 * -1.1.3.7 4-hydroxybenzyl alcohol coprinopsis cinerea 4.81 4.81 1 PMID:29785669 -1.1.3.7 4-hydroxybenzyl alcohol mycosarcoma maydis 75.0 75.0 1 PMID:26452496 -1.1.3.7 4-methoxybenzyl alcohol aspergillus terreus 140.9 140.9 1 PMID:24752075 -1.1.3.7 4-methoxybenzyl alcohol fusarium graminearum 32.0 32.0 1 PMID:34134727 -1.1.3.7 4-methoxybenzyl alcohol fusarium oxysporum f. sp. lycopersici 34.0 34.0 1 PMID:34134727 -1.1.3.7 4-methoxybenzyl alcohol pleurotus eryngii 208.0 104.0 15 PMID:21375505;PMID:21940622;PMID:22271643;PMID:22834786;PMID:25639975;PMID:26162870;PMID:29532900;PMID:31528205 -1.1.3.7 4-nitrobenzaldehyde pleurotus eryngii 1.633 1.633 1 PMID:19891608 -1.1.3.7 5-(hydroxymethyl)furan-2-carboxylic acid colletotrichum graminicola 28.3 28.3 1 * -1.1.3.7 5-(hydroxymethyl)furan-2-carboxylic acid fusarium graminearum 3.8 3.8 1 PMID:34134727 -1.1.3.7 5-(hydroxymethyl)furan-2-carboxylic acid fusarium oxysporum f. sp. lycopersici 5.2 5.2 1 PMID:34134727 -1.1.3.7 5-(hydroxymethyl)furfural methylovorus sp. mp688 1.38 1.38 1 PMID:32503910 -1.1.3.7 5-(hydroxymethyl)furfural pseudomonas nitroreducens 0.24 0.24 1 PMID:32503910 -1.1.3.7 5-(hydroxymethyl)furfural pseudomonas sp. 11/12a 1.0 1.0 1 PMID:32503910 -1.1.3.7 5-formylfuran-2-carboxylate pseudomonas nitroreducens 0.008 0.008 1 PMID:32503910 -1.1.3.7 5-formylfuran-2-carboxylate pseudomonas sp. 11/12a 0.002 0.002 1 PMID:32503910 -1.1.3.7 5-hydroxymethylfurfural colletotrichum graminicola 126.0 126.0 1 * -1.1.3.7 5-hydroxymethylfurfural fusarium graminearum 29.0 29.0 1 PMID:34134727 -1.1.3.7 5-hydroxymethylfurfural fusarium oxysporum f. sp. lycopersici 26.0 26.0 1 PMID:34134727 -1.1.3.7 5-hydroxymethylfurfural pleurotus eryngii 20.1 10.385000000000002 2 PMID:25639975;PMID:31676448 -1.1.3.7 5-hydroxymethylfurfural thermothelomyces thermophilus 0.0008 0.0008 1 PMID:32653619 -1.1.3.7 anisyl alcohol mycosarcoma maydis 45.0 45.0 1 PMID:26452496 -1.1.3.7 anisyl alcohol pleurotus sapidus 203.0 203.0 1 PMID:27138199 -1.1.3.7 anisyl alcohol thermothelomyces thermophilus 0.0075 0.0075 1 PMID:32653619 -1.1.3.7 benzaldehyde pleurotus eryngii 0.5 0.5 1 PMID:19891608 -1.1.3.7 benzyl alcohol aspergillus terreus 2.2 2.2 1 PMID:24752075 -1.1.3.7 benzyl alcohol colletotrichum graminicola 54.5 54.5 1 * -1.1.3.7 benzyl alcohol coprinopsis cinerea 6.13 6.13 1 PMID:29785669 -1.1.3.7 benzyl alcohol fusarium graminearum 37.0 37.0 1 PMID:34134727 -1.1.3.7 benzyl alcohol fusarium oxysporum f. sp. lycopersici 31.0 31.0 1 PMID:34134727 -1.1.3.7 benzyl alcohol pleurotus eryngii 34.4 26.7 6 PMID:15813702;PMID:16999821;PMID:26162870;PMID:29532900 -1.1.3.7 benzyl alcohol pleurotus sapidus 38.0 38.0 1 PMID:27138199 -1.1.3.7 cinnamyl alcohol mycosarcoma maydis 88.0 88.0 1 PMID:26452496 -1.1.3.7 cinnamyl alcohol pleurotus eryngii 65.0 65.0 1 PMID:15813702 -1.1.3.7 cinnamyl alcohol thermothelomyces thermophilus 0.0069 0.0069 1 PMID:32653619 -1.1.3.7 furan-2,5-dicarbaldehyde methylovorus sp. mp688 0.1 0.1 1 PMID:32503910 -1.1.3.7 furan-2,5-dicarbaldehyde pseudomonas nitroreducens 0.017 0.017 1 PMID:32503910 -1.1.3.7 furan-2,5-dicarbaldehyde pseudomonas sp. 11/12a 0.01 0.01 1 PMID:32503910 -1.1.3.7 isovanillyl alcohol coprinopsis cinerea 7.02 7.02 1 PMID:29785669 -1.1.3.7 isovanillyl alcohol pleurotus eryngii 127.0 127.0 1 PMID:15813702 -1.1.3.7 m-anisyl alcohol pleurotus pulmonarius 8.27 8.27 1 PMID:10606774 -1.1.3.7 p-anisyl alcohol pleurotus pulmonarius 48.5 48.5 1 PMID:10606774 -1.1.3.7 vanillyl alcohol coprinopsis cinerea 14.7 14.7 1 PMID:29785669 -1.1.3.7 veratraldehyde pleurotus eryngii 0.13 0.13 1 PMID:19891608 -1.1.3.7 veratryl alcohol coprinopsis cinerea 13.2 13.2 1 PMID:29785669 -1.1.3.7 veratryl alcohol fusarium graminearum 41.0 41.0 1 PMID:34134727 -1.1.3.7 veratryl alcohol fusarium oxysporum f. sp. lycopersici 25.0 25.0 1 PMID:34134727 -1.1.3.7 veratryl alcohol mycosarcoma maydis 53.0 53.0 1 PMID:26452496 -1.1.3.7 veratryl alcohol pleurotus eryngii 114.0 61.45 6 PMID:15813702;PMID:16999821;PMID:26162870;PMID:29532900 -1.1.3.7 veratryl alcohol pleurotus sapidus 70.0 70.0 1 PMID:27138199 -1.1.3.7 veratryl alcohol thermothelomyces thermophilus 0.0053 0.0053 1 PMID:32653619 -1.1.3.8 l-gulono-1,4-lactone arabidopsis thaliana 0.005 0.005 1 PMID:30112455 -1.1.3.9 1-methyl-alpha-d-galactopyranoside fusarium sp. 995.0 995.0 1 PMID:15047910 -1.1.3.9 1-o-methyl beta-d-galactopyranoside hypomyces rosellus 325.0 325.0 1 PMID:2820469 -1.1.3.9 1-o-methyl-alpha-d-galactopyranoside hypomyces rosellus 1165.0 49.0 3 PMID:19290629 -1.1.3.9 1-o-methyl-beta-d-galactopyranoside hypomyces rosellus 1440.0 1440.0 1 PMID:20059 -1.1.3.9 2-methylene-1,3-propanediol fusarium graminearum 283.0 283.0 1 PMID:17385891 -1.1.3.9 d-galactose fusarium graminearum 1100.0 503.0 3 PMID:17385891;PMID:21264996;PMID:26518347 -1.1.3.9 d-galactose fusarium sp. 1090.0 1090.0 1 PMID:15047910 -1.1.3.9 d-galactose fusarium subglutinans 12243.0 12243.0 1 PMID:31177409 -1.1.3.9 d-galactose hypomyces rosellus 1180.0 440.0 5 PMID:4441089;PMID:6890617;PMID:7192504;PMID:7929198 -1.1.3.9 galactoglucomannan fusarium graminearum 3.25 3.25 1 PMID:26518347 -1.1.3.9 galactoxyloglucan fusarium graminearum 3.68 3.68 1 PMID:26518347 -1.1.3.9 guar fusarium sp. 42.8 42.8 1 PMID:15047910 -1.1.3.9 guar galactomannan fusarium graminearum 5.18 5.18 1 PMID:26518347 -1.1.3.9 locust bean galactomannan fusarium graminearum 4.3 4.3 1 PMID:26518347 -1.1.5.10 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide pseudomonas putida 128.0 128.0 1 PMID:28847921 -1.1.5.10 d-2-hydroxybutyrate pseudomonas putida 66.0 66.0 1 PMID:28847921 -1.1.5.10 d-glycerate pseudomonas putida 8.0 8.0 1 PMID:28847921 -1.1.5.10 d-lactate pseudomonas putida 120.0 120.0 1 PMID:28847921 -1.1.5.10 l-lactate pseudomonas putida 9.5 9.5 1 PMID:28847921 -1.1.5.10 ubiquinone-10 pseudomonas putida 2.4 2.4 1 PMID:28847921 -1.1.5.12 (r)-lactate pseudomonas putida kt2440 120.0 68.5 2 PMID:28847921 -1.1.5.12 (s)-lactate pseudomonas putida kt2440 9.5 5.5 2 PMID:28847921 -1.1.5.12 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide pseudomonas putida kt2440 128.0 66.65 2 PMID:28847921 -1.1.5.12 coenzyme q10 pseudomonas putida kt2440 2.4 2.4 1 PMID:28847921 -1.1.5.12 cytochrome c pseudomonas putida kt2440 2.0 1.245 2 PMID:28847921 -1.1.5.12 d-2-hydroxybutanoate pseudomonas putida kt2440 66.0 39.5 2 PMID:28847921 -1.1.5.12 d-glycerate pseudomonas putida kt2440 8.0 4.39 2 PMID:28847921 -1.1.5.13 l-2-hydroxyglutarate arabidopsis thaliana 613.0 613.0 1 PMID:26203119 -1.1.5.13 l-2-hydroxyglutarate escherichia coli 0.08 0.08 1 PMID:18390652 -1.1.5.14 d-fructose gluconobacter sp. 250.0 172.5 2 PMID:8436220 -1.1.5.14 ferricyanide gluconobacter sp. 162.0 127.5 2 PMID:8436220 -1.1.5.2 2-deoxy-d-glucose acinetobacter calcoaceticus 331.0 331.0 1 PMID:10544015 -1.1.5.2 2-deoxy-d-glucose gluconacetobacter diazotrophicus 180.6 180.6 1 PMID:25576305 -1.1.5.2 2-deoxy-d-glucose thermus thermophilus 1141.0 1141.0 1 PMID:27592307 -1.1.5.2 3-o-methyl-d-glucose acinetobacter calcoaceticus 3011.0 2230.5 2 PMID:10544015;PMID:15113562 -1.1.5.2 3-o-methyl-d-glucose escherichia coli 3011.0 3011.0 1 * -1.1.5.2 allose acinetobacter calcoaceticus 2509.0 2509.0 1 PMID:15113562 -1.1.5.2 allose escherichia coli 2509.0 2509.0 1 * -1.1.5.2 alpha-d-lactose thermus thermophilus 1953.0 1953.0 1 PMID:27592307 -1.1.5.2 cellobiose acinetobacter calcoaceticus 1355.0 1355.0 1 PMID:15113562 -1.1.5.2 d-allose acinetobacter calcoaceticus 1440.0 1440.0 1 PMID:10544015 -1.1.5.2 d-cellobiose thermus thermophilus 1042.0 1042.0 1 PMID:27592307 -1.1.5.2 d-galactose acinetobacter calcoaceticus 232.0 176.5 2 PMID:10544015;PMID:15113562 -1.1.5.2 d-galactose escherichia coli 232.0 232.0 1 * -1.1.5.2 d-galactose gluconacetobacter diazotrophicus 160.5 160.5 1 PMID:25576305 -1.1.5.2 d-galactose pyrobaculum aerophilum 4.3 4.3 1 PMID:20692227 -1.1.5.2 d-galactose thermus thermophilus 823.0 823.0 1 PMID:27592307 -1.1.5.2 d-glucosamine thermus thermophilus 197.0 197.0 1 PMID:27592307 -1.1.5.2 d-glucose acinetobacter calcoaceticus 3860.0 3440.0 5 PMID:10544015;PMID:14741705;PMID:15113562;PMID:15571780;PMID:21780841 -1.1.5.2 d-glucose escherichia coli 3860.0 3610.0 2 PMID:16864586 -1.1.5.2 d-glucose gluconacetobacter diazotrophicus 186.3 186.3 1 PMID:25576305 -1.1.5.2 d-glucose pyrobaculum aerophilum 4.1 4.1 1 PMID:20692227 -1.1.5.2 d-glucose sorangium cellulosum 1779.0 1779.0 1 PMID:20886312 -1.1.5.2 d-glucose thermus thermophilus 1054.0 1054.0 1 PMID:27592307 -1.1.5.2 d-glucose 6-phosphate thermus thermophilus 192.0 192.0 1 PMID:27592307 -1.1.5.2 d-mannose acinetobacter calcoaceticus 267.0 267.0 1 PMID:10544015 -1.1.5.2 d-mannose pyrobaculum aerophilum 3.1 3.1 1 PMID:20692227 -1.1.5.2 d-mannose thermus thermophilus 1627.0 1627.0 1 PMID:27592307 -1.1.5.2 d-ribose thermus thermophilus 260.0 260.0 1 PMID:27592307 -1.1.5.2 d-xylose acinetobacter calcoaceticus 201.0 201.0 1 PMID:10544015 -1.1.5.2 d-xylose pyrobaculum aerophilum 3.2 3.2 1 PMID:20692227 -1.1.5.2 d-xylose thermus thermophilus 1681.0 1681.0 1 PMID:27592307 -1.1.5.2 ethanol thermus thermophilus 123.0 123.0 1 PMID:27592307 -1.1.5.2 l-arabinose thermus thermophilus 1755.0 1755.0 1 PMID:27592307 -1.1.5.2 lactose acinetobacter calcoaceticus 1659.0 1164.0 2 PMID:10544015;PMID:15113562 -1.1.5.2 lactose escherichia coli 1659.0 1659.0 1 * -1.1.5.2 maltose acinetobacter calcoaceticus 1930.0 1357.5 2 PMID:10544015;PMID:15113562 -1.1.5.2 maltose escherichia coli 2870.0 2400.0 2 PMID:16864586 -1.1.5.2 maltose pyrobaculum aerophilum 2.3 2.3 1 PMID:20692227 -1.1.5.2 maltose thermus thermophilus 1022.0 1022.0 1 PMID:27592307 -1.1.5.2 maltotriose escherichia coli 2270.0 2270.0 1 PMID:16864586 -1.1.5.2 maltotriose thermus thermophilus 772.0 772.0 1 PMID:27592307 -1.1.5.2 mannitol thermus thermophilus 38.0 38.0 1 PMID:27592307 -1.1.5.2 methanol thermus thermophilus 76.0 76.0 1 PMID:27592307 -1.1.5.2 xylitol thermus thermophilus 15.0 15.0 1 PMID:27592307 -1.1.5.3 glycerol 3-phosphate escherichia coli 33.3 33.3 1 PMID:6792201 -1.1.5.4 (s)-malate pseudomonas taetrolens 7.35 7.35 1 PMID:33166455 -1.1.5.4 cellobiose pseudomonas taetrolens 10.55 10.55 1 PMID:33166455 -1.1.5.4 lactose pseudomonas taetrolens 14.67 14.67 1 PMID:33166455 -1.1.5.4 maltose pseudomonas taetrolens 7.22 7.22 1 PMID:33166455 -1.1.5.5 1-propanol pseudomonas putida 73.1 32.6 3 PMID:24036413;PMID:25229857 -1.1.5.5 acetaldehyde komagataeibacter xylinus 30.8 30.8 1 PMID:20559622 -1.1.5.5 acetaldehyde pseudomonas putida 31.1 31.1 1 PMID:24036413 -1.1.5.5 allylic alcohol komagataeibacter xylinus 67.5 67.5 1 PMID:20559622 -1.1.5.5 ethanol komagataeibacter xylinus 71.0 71.0 1 PMID:20559622 -1.1.5.5 ethanol pseudomonas putida 56.6 24.85 4 PMID:24036413;PMID:25229857 -1.1.5.5 n-butanol komagataeibacter xylinus 52.3 52.3 1 PMID:20559622 -1.1.5.5 propionaldehyde pseudomonas putida 22.0 22.0 1 PMID:24036413 -1.1.5.5 ubiquinone-1 komagataeibacter xylinus 76.3 76.3 1 PMID:20559622 -1.1.5.9 d-glucose acinetobacter baumannii 5330.0 5330.0 1 PMID:14257587 -1.1.5.9 d-glucose aspergillus flavus 780.0 780.0 1 PMID:25650345 -1.1.5.9 d-glucose burkholderia cepacia 69.54 69.54 1 PMID:23695009 -1.1.5.9 d-glucose colletotrichum gloeosporioides 418.0 280.0 4 PMID:22151971 -1.1.5.9 d-glucose mucor circinelloides 749.7 749.7 1 PMID:25912449 -1.1.5.9 d-xylose colletotrichum gloeosporioides 61.0 56.5 4 PMID:22151971 -1.1.5.9 fe(cn)63- aspergillus terreus 230.0 230.0 1 PMID:16556981 -1.1.9.1 (r)-3-bromo-2-methyl-1-propanol comamonas testosteroni 20.3 20.3 1 PMID:8001568 -1.1.9.1 (r)-solketal comamonas testosteroni 2.12 2.12 1 PMID:8001568 -1.1.9.1 (r)-solketal aldehyde comamonas testosteroni 8.3 8.3 1 PMID:8001568 -1.1.9.1 (s)-solketal comamonas testosteroni 0.18 0.18 1 PMID:8001568 -1.1.9.1 (s)-solketal aldehyde comamonas testosteroni 17.1 17.1 1 PMID:8001568 -1.1.9.1 ethanal comamonas testosteroni 19.9 19.9 1 PMID:8001568 -1.1.9.1 ethanol comamonas testosteroni 17.9 17.7 2 PMID:12686148;PMID:8001568 -1.1.98.2 d-glucose 6-phosphate mycobacterium tuberculosis 1.4 1.4 1 PMID:27603793 -1.1.98.2 d-glucose 6-phosphate rhodococcus jostii 17.0 17.0 1 PMID:27966048 -1.1.98.2 oxidized coenzyme f420 mycobacterium tuberculosis 1.4 1.4 1 PMID:27603793 -1.1.98.5 (r)-2-butanol methanofollis liminatans 51.3 51.3 1 PMID:1879431 -1.1.98.5 (s)-2-butanol methanofollis liminatans 38.5 38.5 1 PMID:1879431 -1.1.98.5 2-butanol methanofollis liminatans 49.0 49.0 1 PMID:1879431 -1.1.98.5 2-butanone methanofollis liminatans 2.1 2.1 1 PMID:1879431 -1.1.98.5 2-pentanol methanofollis liminatans 23.1 23.1 1 PMID:1879431 -1.1.98.5 2-pentanone methanofollis liminatans 1.3 1.3 1 PMID:1879431 -1.1.98.5 2-propanol methanofollis liminatans 85.0 85.0 1 PMID:1879431 -1.1.98.5 cyclopentanol methanofollis liminatans 12.8 12.8 1 PMID:1879431 -1.1.98.5 cyclopentanone methanofollis liminatans 4.4 4.4 1 PMID:1879431 -1.1.98.5 oxidized coenzyme f420 methanofollis liminatans 85.0 85.0 1 PMID:1879431 -1.1.98.5 propanone methanofollis liminatans 161.5 161.5 1 PMID:1879431 -1.1.98.5 reduced coenzyme f420 methanofollis liminatans 161.5 161.5 1 PMID:1879431 -1.1.99.13 d-cellobiose agaricus bisporus 141.0 141.0 1 * -1.1.99.13 d-galactose agaricus bisporus 145.0 145.0 1 * -1.1.99.13 d-glucose agaricus bisporus 143.0 143.0 1 * -1.1.99.13 d-maltose agaricus bisporus 154.0 154.0 1 * -1.1.99.13 d-xylose agaricus bisporus 200.0 200.0 1 * -1.1.99.13 l-arabinose agaricus bisporus 239.0 239.0 1 * -1.1.99.13 sucrose agaricus bisporus 59.0 59.0 1 * -1.1.99.14 d-lactate chlamydomonas reinhardtii 5.42 5.42 1 PMID:24681750 -1.1.99.14 glycolate chlamydomonas reinhardtii 1.93 1.93 1 PMID:24681750 -1.1.99.14 l-lactate chlamydomonas reinhardtii 5.42 5.42 1 PMID:24681750 -1.1.99.18 1,4-benzoquinone gelatoporia subvermispora 45.0 45.0 1 PMID:19270118 -1.1.99.18 1,4-benzoquinone thermothelomyces myriococcoides 43.0 31.3 2 PMID:23617537 -1.1.99.18 1,4-benzoquinone trametes pubescens 27.5 27.5 1 PMID:14666391 -1.1.99.18 1,4-benzoquinone trametes villosa 20.8 20.8 1 PMID:14666391 -1.1.99.18 2,6-dichloroindophenol gelatoporia subvermispora 29.0 29.0 1 PMID:19270118 -1.1.99.18 2,6-dichloroindophenol phanerodontia chrysosporium 24.4 24.4 1 PMID:33407462 -1.1.99.18 2,6-dichloroindophenol thermothelomyces myriococcoides 17.4 17.1 2 PMID:34306835 -1.1.99.18 2,6-dichlorophenol indophenol amesia atrobrunnea 17.0 17.0 1 PMID:22471986 -1.1.99.18 2,6-dichlorophenol indophenol dichomera saubinetii 22.6 22.6 1 PMID:22471986 -1.1.99.18 2,6-dichlorophenol indophenol fungi 11.3 7.6 3 PMID:14714477 -1.1.99.18 2,6-dichlorophenol indophenol hypoxylon haematostroma 13.5 13.5 1 PMID:22471986 -1.1.99.18 2,6-dichlorophenol indophenol neurospora crassa 24.8 24.8 1 PMID:22471986 -1.1.99.18 2,6-dichlorophenol indophenol phanerodontia chrysosporium 27.0 27.0 1 PMID:12796496 -1.1.99.18 2,6-dichlorophenol indophenol stachybotrys bisbyi 4.0 4.0 1 PMID:22471986 -1.1.99.18 2,6-dichlorophenol indophenol termitomyces clypeatus 16.01 16.01 1 * -1.1.99.18 2,6-dichlorophenol indophenol thermothelomyces fergusii 53.8 53.8 1 PMID:22471986 -1.1.99.18 2,6-dichlorophenol indophenol thermothelomyces myriococcoides 4.1 4.1 1 PMID:23617537 -1.1.99.18 2,6-dichlorophenol indophenol trametes pubescens 25.6 25.6 1 PMID:14666391 -1.1.99.18 2,6-dichlorophenol indophenol trametes villosa 38.1 38.1 1 PMID:14666391 -1.1.99.18 2,6-dichlorophenol-indophenol thermothielavioides terrestris 2.05 2.05 1 PMID:22484439 -1.1.99.18 2,6-dichlorophenolindophenol mycothermus thermophilus 17.0 17.0 1 PMID:9461557 -1.1.99.18 2,6-dichlorophenolindophenol thermothelomyces heterothallicus 18.3 12.9 2 PMID:10328816 -1.1.99.18 2,6-dichlorphenolindophenol mycothermus thermophilus 17.0 17.0 1 * -1.1.99.18 2,6-dichlorphenolindophenol schizophyllum commune 63.0 63.0 1 PMID:9578598 -1.1.99.18 3,5 di-tert-butyl-o-benzoquinone phanerodontia chrysosporium 17.0 17.0 1 PMID:8369336 -1.1.99.18 3,5-di-tert-butyl-1,2-benzoquinone trametes pubescens 24.2 24.2 1 PMID:14666391 -1.1.99.18 3,5-di-tert-butyl-1,2-benzoquinone trametes villosa 16.9 16.9 1 PMID:14666391 -1.1.99.18 6'-azido-6'-deoxy-beta-d-glucopyranosyl-(1->4)-d-glucopyranose agroathelia rolfsii 17.7 17.7 1 PMID:24211370 -1.1.99.18 alpha-lactose agroathelia rolfsii 17.0 17.0 1 PMID:11282631 -1.1.99.18 alpha-lactose termitomyces clypeatus 14.22 14.22 1 * -1.1.99.18 benzoquinone mycothermus thermophilus 21.0 21.0 1 PMID:9461557 -1.1.99.18 beta-d-glucopyranosyl-(1->4)-2-azido-2-deoxy-d-glucopyranose agroathelia rolfsii 0.9 0.9 1 PMID:24211370 -1.1.99.18 beta-d-glucopyranosyl-(1->4)-6-azido-6-deoxy-d-glucopyranose agroathelia rolfsii 9.1 9.1 1 PMID:24211370 -1.1.99.18 cellobiose agroathelia rolfsii 37.0 25.5 10 PMID:11282631;PMID:24211370 -1.1.99.18 cellobiose amesia atrobrunnea 20.1 13.9 2 PMID:21216904;PMID:22471986 -1.1.99.18 cellobiose arabidopsis thaliana 1.22 1.22 1 PMID:30664296 -1.1.99.18 cellobiose cerrena unicolor 19.06 18.86 3 PMID:26003328;PMID:29418014 -1.1.99.18 cellobiose coprinopsis cinerea 96.9 96.9 1 PMID:22940800 -1.1.99.18 cellobiose dichomera saubinetii 27.8 18.6 2 PMID:21216904;PMID:22471986 -1.1.99.18 cellobiose fungi 8.9 7.9 3 PMID:14714477 -1.1.99.18 cellobiose gelatoporia subvermispora 26.0 25.5 2 PMID:19270118 -1.1.99.18 cellobiose hypoxylon haematostroma 21.8 19.0 2 PMID:21216904;PMID:22471986 -1.1.99.18 cellobiose mycothermus thermophilus 14.0 7.13 2 PMID:9461557 -1.1.99.18 cellobiose neurospora crassa 53.1 13.5 7 PMID:20709172;PMID:21216904;PMID:22471986;PMID:22729546 -1.1.99.18 cellobiose phanerodontia chrysosporium 40.0 15.5 11 PMID:11676020;PMID:12680758;PMID:12796496;PMID:27199949;PMID:31154590;PMID:33407462;PMID:8434950 -1.1.99.18 cellobiose physcomitrium patens 48.0 48.0 1 PMID:29633551 -1.1.99.18 cellobiose podospora anserina 8.56 8.56 1 PMID:22940800 -1.1.99.18 cellobiose schizophyllum commune 13.0 13.0 1 PMID:9578598 -1.1.99.18 cellobiose stachybotrys bisbyi 19.9 11.0 2 PMID:21216904;PMID:22471986 -1.1.99.18 cellobiose termitomyces clypeatus 17.65 17.65 1 * -1.1.99.18 cellobiose termitomyces sp. oe 147 59.56 59.56 1 PMID:33063604 -1.1.99.18 cellobiose thermothelomyces fergusii 15.5 9.95 10 PMID:21216904;PMID:22471986;PMID:28245812 -1.1.99.18 cellobiose thermothelomyces heterothallicus 16.1 11.100000000000001 2 PMID:10328816 -1.1.99.18 cellobiose thermothelomyces myriococcoides 4.11 4.11 1 PMID:23199740 -1.1.99.18 cellobiose thermothielavioides terrestris 1.23 1.23 1 PMID:22484439 -1.1.99.18 cellobiose trametes pubescens 21.9 21.9 1 PMID:14666391 -1.1.99.18 cellobiose trametes sanguinea 11.73 11.73 1 PMID:34132850 -1.1.99.18 cellobiose trametes villosa 23.6 23.6 1 PMID:14666391 -1.1.99.18 cellohexaose arabidopsis thaliana 1.59 1.59 1 PMID:30664296 -1.1.99.18 cellohexaose neurospora crassa 24.7 24.7 1 PMID:20709172 -1.1.99.18 cellopentaose agroathelia rolfsii 24.0 24.0 1 PMID:11282631 -1.1.99.18 cellopentaose arabidopsis thaliana 1.38 1.38 1 PMID:30664296 -1.1.99.18 cellopentaose mycothermus thermophilus 12.0 12.0 1 PMID:9461557 -1.1.99.18 cellopentaose neurospora crassa 46.6 25.7 3 PMID:20709172;PMID:22729546 -1.1.99.18 cellopentaose phanerodontia chrysosporium 21.5 21.5 1 PMID:8434950 -1.1.99.18 cellopentaose schizophyllum commune 10.0 10.0 1 PMID:9578598 -1.1.99.18 cellopentaose termitomyces clypeatus 9.31 9.31 1 * -1.1.99.18 cellopentaose thermothielavioides terrestris 1.23 1.23 1 PMID:22484439 -1.1.99.18 cellopentaose trametes pubescens 13.9 13.9 1 PMID:14666391 -1.1.99.18 cellopentaose trametes villosa 14.7 14.7 1 PMID:14666391 -1.1.99.18 cellotetraose agroathelia rolfsii 24.0 24.0 1 PMID:11282631 -1.1.99.18 cellotetraose arabidopsis thaliana 1.6 1.6 1 PMID:30664296 -1.1.99.18 cellotetraose coprinopsis cinerea 101.6 101.6 1 PMID:22940800 -1.1.99.18 cellotetraose mycothermus thermophilus 12.0 12.0 1 PMID:9461557 -1.1.99.18 cellotetraose neurospora crassa 46.0 23.9 3 PMID:20709172;PMID:22729546 -1.1.99.18 cellotetraose phanerodontia chrysosporium 20.7 20.7 1 PMID:8434950 -1.1.99.18 cellotetraose podospora anserina 4.0 4.0 1 PMID:22940800 -1.1.99.18 cellotetraose schizophyllum commune 12.0 12.0 1 PMID:9578598 -1.1.99.18 cellotetraose termitomyces clypeatus 8.88 8.88 1 * -1.1.99.18 cellotetraose thermothelomyces heterothallicus 15.1 10.6 2 PMID:10328816 -1.1.99.18 cellotetraose thermothelomyces myriococcoides 2.7 2.7 1 PMID:23199740 -1.1.99.18 cellotetraose thermothielavioides terrestris 1.23 1.23 1 PMID:22484439 -1.1.99.18 cellotetraose trametes pubescens 15.0 15.0 1 PMID:14666391 -1.1.99.18 cellotetraose trametes villosa 14.2 14.2 1 PMID:14666391 -1.1.99.18 cellotriose agroathelia rolfsii 26.0 26.0 1 PMID:11282631 -1.1.99.18 cellotriose arabidopsis thaliana 4.49 4.49 1 PMID:30664296 -1.1.99.18 cellotriose coprinopsis cinerea 156.0 156.0 1 PMID:22940800 -1.1.99.18 cellotriose mycothermus thermophilus 12.0 12.0 1 PMID:9461557 -1.1.99.18 cellotriose neurospora crassa 49.7 24.78 3 PMID:20709172;PMID:22729546 -1.1.99.18 cellotriose phanerodontia chrysosporium 24.0 24.0 1 PMID:8434950 -1.1.99.18 cellotriose podospora anserina 3.8 3.8 1 PMID:22940800 -1.1.99.18 cellotriose schizophyllum commune 12.0 12.0 1 PMID:9578598 -1.1.99.18 cellotriose termitomyces clypeatus 8.88 8.88 1 * -1.1.99.18 cellotriose thermothielavioides terrestris 1.25 1.25 1 PMID:22484439 -1.1.99.18 cellulose phanerodontia chrysosporium 0.4 0.4 1 * -1.1.99.18 cytochrome c amesia atrobrunnea 21.3 21.3 1 PMID:22471986 -1.1.99.18 cytochrome c dichomera saubinetii 25.2 25.2 1 PMID:22471986 -1.1.99.18 cytochrome c fungi 11.3 8.1 3 PMID:14714477 -1.1.99.18 cytochrome c gelatoporia subvermispora 60.0 60.0 1 PMID:19270118 -1.1.99.18 cytochrome c hypoxylon haematostroma 18.1 18.1 1 PMID:22471986 -1.1.99.18 cytochrome c mycothermus thermophilus 27.0 27.0 1 PMID:9461557 -1.1.99.18 cytochrome c neurospora crassa 28.7 28.7 1 PMID:22471986 -1.1.99.18 cytochrome c phanerodontia chrysosporium 37.3 14.5 6 PMID:11063597;PMID:11676020;PMID:12796496;PMID:33407462;PMID:8369336 -1.1.99.18 cytochrome c schizophyllum commune 25.0 25.0 1 PMID:9578598 -1.1.99.18 cytochrome c stachybotrys bisbyi 4.9 4.9 1 PMID:22471986 -1.1.99.18 cytochrome c termitomyces clypeatus 19.69 19.69 1 * -1.1.99.18 cytochrome c thermothelomyces fergusii 21.4 21.4 1 PMID:22471986 -1.1.99.18 cytochrome c thermothelomyces heterothallicus 20.8 14.05 2 PMID:10328816 -1.1.99.18 cytochrome c thermothelomyces myriococcoides 6.3 6.3 1 PMID:34306835 -1.1.99.18 cytochrome c trametes pubescens 29.4 29.4 1 PMID:14666391 -1.1.99.18 cytochrome c trametes villosa 32.5 32.5 1 PMID:14666391 -1.1.99.18 d-galactose neurospora crassa 3.6 2.55 2 PMID:22729546 -1.1.99.18 d-glucose amesia atrobrunnea 16.8 11.95 2 PMID:21216904;PMID:22471986 -1.1.99.18 d-glucose coprinopsis cinerea 34.4 34.4 1 PMID:22940800 -1.1.99.18 d-glucose dichomera saubinetii 23.6 19.9 2 PMID:21216904;PMID:22471986 -1.1.99.18 d-glucose gelatoporia subvermispora 3.8 3.5999999999999996 2 PMID:19270118 -1.1.99.18 d-glucose hypoxylon haematostroma 18.4 9.45 2 PMID:21216904;PMID:22471986 -1.1.99.18 d-glucose mycothermus thermophilus 0.23 0.23 1 * -1.1.99.18 d-glucose neurospora crassa 55.0 22.900000000000002 4 PMID:21216904;PMID:22471986;PMID:22729546 -1.1.99.18 d-glucose phanerodontia chrysosporium 7.8 4.51 2 PMID:33407462 -1.1.99.18 d-glucose podospora anserina 1.6 1.6 1 PMID:22940800 -1.1.99.18 d-glucose stachybotrys bisbyi 24.2 12.9 2 PMID:21216904;PMID:22471986 -1.1.99.18 d-glucose thermothelomyces fergusii 25.6 10.0 3 PMID:21216904;PMID:22471986 -1.1.99.18 d-glucose thermothelomyces myriococcoides 4.8 4.8 1 PMID:23199740 -1.1.99.18 d-glucose thermothielavioides terrestris 1.01 1.01 1 PMID:22484439 -1.1.99.18 d-glucose trametes pubescens 1.31 1.31 1 PMID:14666391 -1.1.99.18 d-mannose neurospora crassa 4.7 4.5 2 PMID:22729546 -1.1.99.18 d-xylose neurospora crassa 1.9 1.7 2 PMID:22729546 -1.1.99.18 d-xylose thermothielavioides terrestris 0.33 0.33 1 PMID:22484439 -1.1.99.18 fad phanerodontia chrysosporium 74.0 74.0 1 PMID:11063597 -1.1.99.18 ferricenium gelatoporia subvermispora 58.0 58.0 1 PMID:19270118 -1.1.99.18 ferricenium ion trametes pubescens 34.7 34.7 1 PMID:14666391 -1.1.99.18 ferricenium ion trametes villosa 35.6 35.6 1 PMID:14666391 -1.1.99.18 ferricyanide gelatoporia subvermispora 61.0 61.0 1 PMID:19270118 -1.1.99.18 ferricyanide mycothermus thermophilus 14.0 14.0 1 PMID:9461557 -1.1.99.18 ferricyanide phanerodontia chrysosporium 5.5 5.5 1 PMID:8369336 -1.1.99.18 ferricyanide schizophyllum commune 13.5 13.5 1 PMID:9578598 -1.1.99.18 ferricyanide termitomyces clypeatus 31.36 31.36 1 * -1.1.99.18 ferricyanide thermothelomyces heterothallicus 24.1 18.450000000000003 2 PMID:10328816 -1.1.99.18 ferricytochrome c phanerodontia chrysosporium 20.5 20.5 1 PMID:8434950 -1.1.99.18 ferricytochrome c thermothelomyces myriococcoides 2.1 1.55 10 PMID:25913436 -1.1.99.18 galactobiose neurospora crassa 1.4 1.4 1 PMID:20709172 -1.1.99.18 galactose neurospora crassa 2.1 2.1 1 PMID:20709172 -1.1.99.18 glucose neurospora crassa 7.6 7.6 1 PMID:20709172 -1.1.99.18 glucose trametes villosa 1.92 1.92 1 PMID:14666391 -1.1.99.18 k3fe(cn)6 trametes pubescens 27.8 27.8 1 PMID:14666391 -1.1.99.18 k3fe(cn)6 trametes villosa 36.9 36.9 1 PMID:14666391 -1.1.99.18 lactose agroathelia rolfsii 26.0 26.0 1 PMID:11282631 -1.1.99.18 lactose amesia atrobrunnea 33.7 20.950000000000003 2 PMID:21216904;PMID:22471986 -1.1.99.18 lactose cerrena unicolor 20.86 19.46 3 PMID:26003328;PMID:29418014 -1.1.99.18 lactose coprinopsis cinerea 136.3 136.3 1 PMID:22940800 -1.1.99.18 lactose dichomera saubinetii 28.9 19.049999999999997 2 PMID:21216904;PMID:22471986 -1.1.99.18 lactose fungi 14.0 14.0 1 PMID:14714477 -1.1.99.18 lactose gelatoporia subvermispora 27.0 17.5 2 PMID:19270118 -1.1.99.18 lactose hypoxylon haematostroma 25.0 14.45 2 PMID:21216904;PMID:22471986 -1.1.99.18 lactose mycothermus thermophilus 14.0 7.165 2 PMID:9461557 -1.1.99.18 lactose neurospora crassa 51.8 11.8 5 PMID:20709172;PMID:21216904;PMID:22471986;PMID:22729546 -1.1.99.18 lactose phanerochaete sordida 14.0 14.0 1 * -1.1.99.18 lactose phanerodontia chrysosporium 32.3 13.850000000000001 6 PMID:12680758;PMID:31154590;PMID:33407462;PMID:8434950 -1.1.99.18 lactose physcomitrium patens 8.0 8.0 1 PMID:29633551 -1.1.99.18 lactose podospora anserina 2.6 2.6 1 PMID:22940800 -1.1.99.18 lactose schizophyllum commune 6.0 6.0 1 PMID:9578598 -1.1.99.18 lactose stachybotrys bisbyi 20.2 11.25 2 PMID:21216904;PMID:22471986 -1.1.99.18 lactose termitomyces sp. oe 147 66.95 66.95 1 PMID:33063604 -1.1.99.18 lactose thermothelomyces fergusii 24.7 10.9 3 PMID:21216904;PMID:22471986 -1.1.99.18 lactose thermothelomyces heterothallicus 16.8 11.350000000000001 2 PMID:10328816 -1.1.99.18 lactose thermothelomyces myriococcoides 17.2 10.94 2 PMID:23199740 -1.1.99.18 lactose thermothielavioides terrestris 1.4 1.4 1 PMID:22484439 -1.1.99.18 lactose trametes pubescens 25.8 25.8 1 PMID:14666391 -1.1.99.18 lactose trametes sanguinea 14.3 14.3 1 PMID:34132850 -1.1.99.18 lactose trametes villosa 26.9 26.9 1 PMID:14666391 -1.1.99.18 maltose amesia atrobrunnea 4.0 2.5 2 PMID:21216904;PMID:22471986 -1.1.99.18 maltose dichomera saubinetii 1.38 1.29 2 PMID:21216904;PMID:22471986 -1.1.99.18 maltose gelatoporia subvermispora 1.03 0.97 2 PMID:19270118 -1.1.99.18 maltose hypoxylon haematostroma 3.6 2.525 2 PMID:21216904;PMID:22471986 -1.1.99.18 maltose mycothermus thermophilus 1.2 0.6265 2 PMID:9461557 -1.1.99.18 maltose neurospora crassa 20.5 0.6 5 PMID:20709172;PMID:21216904;PMID:22471986;PMID:22729546 -1.1.99.18 maltose stachybotrys bisbyi 0.51 0.355 2 PMID:21216904;PMID:22471986 -1.1.99.18 maltose termitomyces sp. oe 147 8.52 8.52 1 PMID:33063604 -1.1.99.18 maltose thermothelomyces fergusii 5.0 1.8 3 PMID:21216904;PMID:22471986 -1.1.99.18 maltose thermothelomyces myriococcoides 0.315 0.315 1 PMID:23199740 -1.1.99.18 maltose thermothielavioides terrestris 0.17 0.17 1 PMID:22484439 -1.1.99.18 maltose trametes pubescens 1.92 1.92 1 PMID:14666391 -1.1.99.18 maltose trametes villosa 2.08 2.08 1 PMID:14666391 -1.1.99.18 maltotetraose neurospora crassa 2.2 1.8 2 PMID:22729546 -1.1.99.18 maltotetraose thermothelomyces myriococcoides 0.48 0.48 1 PMID:23199740 -1.1.99.18 maltotriose neurospora crassa 1.8 1.4 2 PMID:22729546 -1.1.99.18 mannobiose neurospora crassa 2.1 2.1 1 PMID:20709172 -1.1.99.18 mannopentaose neurospora crassa 19.8 13.600000000000001 2 PMID:22729546 -1.1.99.18 mannose neurospora crassa 10.2 10.2 1 PMID:20709172 -1.1.99.18 o2 thermothelomyces myriococcoides 0.16 0.09 3 PMID:19506859;PMID:23617537 -1.1.99.18 thiocellobiose agroathelia rolfsii 27.0 27.0 1 PMID:11282631 -1.1.99.18 thiocellobiose trametes pubescens 19.4 19.4 1 PMID:14666391 -1.1.99.18 thiocellobiose trametes villosa 21.4 21.4 1 PMID:14666391 -1.1.99.18 triiodide ion phanerodontia chrysosporium 17.0 17.0 1 PMID:8369336 -1.1.99.18 ubiquinone phanerodontia chrysosporium 44.2 43.85 2 PMID:11676020 -1.1.99.18 xylobiose agroathelia rolfsii 27.0 27.0 1 PMID:11282631 -1.1.99.18 xylobiose mycothermus thermophilus 3.0 1.559 2 PMID:9461557 -1.1.99.18 xylobiose neurospora crassa 45.4 5.8 3 PMID:20709172;PMID:22729546 -1.1.99.18 xylobiose trametes pubescens 18.3 18.3 1 PMID:14666391 -1.1.99.18 xylobiose trametes villosa 17.2 17.2 1 PMID:14666391 -1.1.99.18 xylose neurospora crassa 4.6 4.6 1 PMID:20709172 -1.1.99.18 xylotriose neurospora crassa 6.0 4.15 2 PMID:22729546 -1.1.99.2 (s)-2-hydroxyglutarate arabidopsis thaliana 613.0 613.0 1 PMID:26203119 -1.1.99.20 peg-1000 ensifer sp. as08 12.0 12.0 1 PMID:23306149 -1.1.99.20 peg-mono-4-nonylphenyl ether, averaging 10 ethoxy units ensifer sp. as08 11.0 11.0 1 PMID:23306149 -1.1.99.21 d-sorbitol gluconobacter oxydans 3820.0 3820.0 1 PMID:27633501 -1.1.99.28 d-fructose zymomonas mobilis 200.0 200.0 1 PMID:3745122 -1.1.99.28 d-glucose zymomonas mobilis 200.0 200.0 1 PMID:3745122 -1.1.99.28 gluconolactone zymomonas mobilis 0.8 0.8 1 PMID:3745122 -1.1.99.28 sorbitol zymomonas mobilis 0.8 0.8 1 PMID:3745122 -1.1.99.29 1,4-benzoquinone agaricus bisporus 44.2 44.2 1 PMID:26616098 -1.1.99.29 1,4-benzoquinone agaricus campestris 34.82 34.82 1 PMID:24970179 -1.1.99.29 1,4-benzoquinone agaricus xanthodermus 12.89 12.89 1 PMID:24970179 -1.1.99.29 1,4-benzoquinone macropsalliota meleagris 76.0 65.4 8 PMID:19888575;PMID:22080342;PMID:24614932;PMID:27995309 -1.1.99.29 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) agaricus bisporus 101.2 101.2 1 PMID:26616098 -1.1.99.29 2,2'-azino-bis[3-ethylbenzothiazoline]-6-sulfonic acid macropsalliota meleagris 7.57 5.32 3 PMID:27995309 -1.1.99.29 2,6-dichlorophenolindophenol agaricus bisporus 57.6 57.6 1 PMID:26616098 -1.1.99.29 2,6-dichlorophenolindophenol agaricus campestris 10.56 10.56 1 PMID:24970179 -1.1.99.29 2,6-dichlorophenolindophenol agaricus xanthodermus 7.65 7.65 1 PMID:24970179 -1.1.99.29 2,6-dichlorophenolindophenol macropsalliota meleagris 40.7 40.7 1 PMID:24614932 -1.1.99.29 2-chloro-1,4-benzoquinone macropsalliota meleagris 15.1 14.0 4 PMID:19888575;PMID:22080342 -1.1.99.29 cellobiose agaricus bisporus 25.63 25.63 1 PMID:26616098 -1.1.99.29 cellobiose macropsalliota meleagris 38.4 38.4 5 PMID:19768457;PMID:28193332 -1.1.99.29 d-allose macropsalliota meleagris 40.2 35.3 3 PMID:27995309 -1.1.99.29 d-fructose macropsalliota meleagris 16.5 16.5 4 PMID:19768457 -1.1.99.29 d-galactose agaricus bisporus 28.7 28.7 1 PMID:26616098 -1.1.99.29 d-galactose agaricus campestris 5.23 5.23 1 PMID:24970179 -1.1.99.29 d-galactose agaricus xanthodermus 24.77 24.77 1 PMID:24970179 -1.1.99.29 d-galactose macropsalliota meleagris 137.0 48.5 13 PMID:19768457;PMID:19888575;PMID:22080342;PMID:24614932;PMID:27995309;PMID:28193332 -1.1.99.29 d-glucose agaricus bisporus 33.7 33.7 1 PMID:26616098 -1.1.99.29 d-glucose agaricus campestris 4.1 4.1 1 PMID:24970179 -1.1.99.29 d-glucose agaricus xanthodermus 13.02 13.02 1 PMID:24970179 -1.1.99.29 d-glucose macropsalliota meleagris 48.06 45.9 13 PMID:19768457;PMID:19888575;PMID:22080342;PMID:24614932;PMID:27995309;PMID:28193332 -1.1.99.29 d-maltose macropsalliota meleagris 43.2 43.2 4 PMID:19768457 -1.1.99.29 d-mannose agaricus bisporus 13.31 13.31 1 PMID:26616098 -1.1.99.29 d-mannose macropsalliota meleagris 109.0 29.3 8 PMID:19768457;PMID:27995309;PMID:28193332 -1.1.99.29 d-ribose macropsalliota meleagris 31.4 31.4 4 PMID:19768457 -1.1.99.29 d-sorbose macropsalliota meleagris 15.7 15.7 3 * -1.1.99.29 d-talose macropsalliota meleagris 21.3 21.3 4 PMID:19768457 -1.1.99.29 d-xylose agaricus bisporus 36.9 36.9 1 PMID:26616098 -1.1.99.29 d-xylose agaricus campestris 6.37 6.37 1 PMID:24970179 -1.1.99.29 d-xylose agaricus xanthodermus 29.16 29.16 1 PMID:24970179 -1.1.99.29 d-xylose macropsalliota meleagris 146.0 43.4 11 PMID:19768457;PMID:19888575;PMID:22080342;PMID:27995309 -1.1.99.29 ferricenium ion macropsalliota meleagris 203.0 104.0 5 PMID:19888575;PMID:27995309 -1.1.99.29 ferrocenium ion agaricus bisporus 111.1 111.1 1 PMID:26616098 -1.1.99.29 ferrocenium ion agaricus campestris 19.92 19.92 1 PMID:24970179 -1.1.99.29 ferrocenium ion agaricus xanthodermus 22.07 22.07 1 PMID:24970179 -1.1.99.29 ferrocenium ion macropsalliota meleagris 130.0 117.0 4 PMID:22080342;PMID:24614932;PMID:28193332 -1.1.99.29 l-arabinose agaricus bisporus 29.6 29.6 1 PMID:26616098 -1.1.99.29 l-arabinose agaricus campestris 3.05 3.05 1 PMID:24970179 -1.1.99.29 l-arabinose agaricus xanthodermus 22.9 22.9 1 PMID:24970179 -1.1.99.29 l-arabinose macropsalliota meleagris 45.7 37.2 8 PMID:19768457;PMID:19888575;PMID:22080342 -1.1.99.29 l-sorbose macropsalliota meleagris 15.7 15.7 1 PMID:19768457 -1.1.99.29 lactose agaricus bisporus 15.95 15.95 1 PMID:26616098 -1.1.99.29 lactose agaricus campestris 3.12 3.12 1 PMID:24970179 -1.1.99.29 lactose agaricus xanthodermus 24.65 24.65 1 PMID:24970179 -1.1.99.29 lactose macropsalliota meleagris 209.0 39.6 12 PMID:19768457;PMID:19888575;PMID:22080342;PMID:24614932;PMID:27995309 -1.1.99.29 maltose agaricus bisporus 27.26 27.26 1 PMID:26616098 -1.1.99.29 maltose macropsalliota meleagris 44.7 7.63 3 PMID:27995309 -1.1.99.29 maltotriose macropsalliota meleagris 35.9 23.6 7 PMID:19768457;PMID:27995309 -1.1.99.29 methyl-alpha-d-glucopyranoside macropsalliota meleagris 85.0 41.5 3 PMID:27995309 -1.1.99.29 raffinose agaricus bisporus 19.61 19.61 1 PMID:26616098 -1.1.99.29 xylobiose macropsalliota meleagris 50.4 50.4 4 PMID:19768457 -1.1.99.31 (s)-3-phenyllactate pseudomonas putida 270.0 270.0 1 PMID:10955993 -1.1.99.31 (s)-mandelate pseudomonas putida 402.0 280.0 10 PMID:10493804;PMID:10955993;PMID:12369819;PMID:14596603;PMID:14604988;PMID:14967029;PMID:15311930;PMID:8241149 -1.1.99.31 (s)-mandelate rhodotorula graminis 109.0 49.0 3 PMID:8439280 -1.1.99.31 2-hydroxy-3-butynoate pseudomonas putida 3.9 3.9 1 PMID:15311930 -1.1.99.31 2-hydroxybutyrate pseudomonas putida 0.1 0.1 1 PMID:15311930 -1.1.99.31 2-hydroxyhexanoate pseudomonas putida 0.34 0.34 1 PMID:15311930 -1.1.99.31 2-hydroxyisocaproate pseudomonas putida 0.8 0.8 1 PMID:15311930 -1.1.99.31 2-hydroxyoctanoate pseudomonas putida 1.0 0.5 3 PMID:15311930;PMID:19465768 -1.1.99.31 2-hydroxyvalerate pseudomonas putida 0.36 0.36 1 PMID:15311930 -1.1.99.31 2-oxo-2-phenylacetate pseudomonas putida 313.0 313.0 1 PMID:14604988 -1.1.99.31 3-hydroxy-dl-mandelate rhodotorula graminis 108.0 108.0 1 PMID:8110205 -1.1.99.31 3-indolelactate pseudomonas putida 3.9 1.0 3 PMID:15311930;PMID:19465768 -1.1.99.31 3-methoxy-dl-mandelate rhodotorula graminis 68.0 68.0 1 PMID:8110205 -1.1.99.31 3-phenyllactate pseudomonas putida 0.52 0.52 1 PMID:15311930 -1.1.99.31 4-bromo-dl-mandelate rhodotorula graminis 108.0 108.0 1 PMID:8110205 -1.1.99.31 4-chloro-dl-mandelate rhodotorula graminis 116.0 92.0 2 PMID:8110205 -1.1.99.31 4-chloromandelate pseudomonas putida 334.0 334.0 1 PMID:15311930 -1.1.99.31 4-fluoro-dl-mandelate rhodotorula graminis 98.0 98.0 1 PMID:8110205 -1.1.99.31 4-hydroxy-dl-mandelate rhodotorula graminis 146.0 146.0 1 PMID:8110205 -1.1.99.31 4-methoxy-dl-mandelate rhodotorula graminis 106.0 106.0 1 PMID:8110205 -1.1.99.31 4-methyl-dl-mandelate rhodotorula graminis 80.0 80.0 1 PMID:8110205 -1.1.99.31 cytochrome c rhodotorula graminis 225.0 225.0 1 PMID:9639569 -1.1.99.31 d,l-mandelate rhodotorula graminis 94.0 94.0 1 PMID:8110205 -1.1.99.31 dl-[2-1h]-mandelate rhodotorula graminis 316.0 300.0 3 PMID:9639569 -1.1.99.31 dl-[2-2h]-mandelate rhodotorula graminis 99.0 92.5 4 PMID:8110205;PMID:9639569 -1.1.99.31 ethyl-(s)-mandelate pseudomonas putida 204.0 204.0 1 PMID:14967029 -1.1.99.31 ferricyanide rhodotorula graminis 550.0 550.0 1 PMID:9639569 -1.1.99.31 indoleglycolate pseudomonas putida 122.0 122.0 1 PMID:15311930 -1.1.99.31 l-mandelate rhodotorula graminis 114.0 114.0 1 PMID:8110205 -1.1.99.31 mandelate pseudomonas putida 350.0 350.0 3 PMID:15311930;PMID:19465768 -1.1.99.31 methyl-(s)-mandelate pseudomonas putida 151.0 151.0 1 PMID:14967029 -1.1.99.31 o2 pseudomonas putida 1.2 1.2 1 PMID:15311930 -1.1.99.32 1,5-anhydro-d-glucitol sinorhizobium sp. 14.1 14.1 1 PMID:25721692 -1.1.99.32 l-sorbose sinorhizobium sp. 11.2 11.2 1 PMID:25721692 -1.1.99.35 2-deoxy-d-glucose acinetobacter calcoaceticus 331.0 331.0 1 PMID:10544015 -1.1.99.35 3-o-methyl-d-glucose acinetobacter calcoaceticus 3011.0 2229.5 2 PMID:10544015 -1.1.99.35 d-allose acinetobacter calcoaceticus 2509.0 1976.0 2 PMID:10544015 -1.1.99.35 d-galactose acinetobacter calcoaceticus 232.0 176.5 2 PMID:10544015 -1.1.99.35 d-glucose acinetobacter calcoaceticus 3860.0 3648.0 2 PMID:10544015 -1.1.99.35 d-lactose acinetobacter calcoaceticus 1659.0 930.0 2 PMID:10544015 -1.1.99.35 d-maltose acinetobacter calcoaceticus 1930.0 1357.5 2 PMID:10544015 -1.1.99.35 d-mannose acinetobacter calcoaceticus 267.0 267.0 1 PMID:10544015 -1.1.99.35 d-xylose acinetobacter calcoaceticus 669.0 669.0 1 PMID:10544015 -1.1.99.35 lactose acinetobacter calcoaceticus 1600.0 965.0 4 * -1.1.99.38 2-deoxy-scyllo-inosamine niallia circulans 0.033 0.033 1 PMID:18001019 -1.1.99.38 s-adenosyl-l-methionine niallia circulans 0.021 0.0205 2 PMID:18001019;PMID:18672902 -1.1.99.39 (r)-2-hydroxyglutarate arabidopsis thaliana 0.8 0.8 1 PMID:19586914 -1.1.99.39 (r)-2-hydroxyglutarate stutzerimonas stutzeri 7.9 7.9 2 PMID:28827360;PMID:30131334 -1.1.99.39 (s)-2-hydroxyglutarate pseudomonas aeruginosa 11.0 11.0 1 PMID:33301690 -1.1.99.39 cytochrome c stutzerimonas stutzeri 1.46 1.46 1 PMID:28827360 -1.1.99.39 electron transfer flavoprotein stutzerimonas stutzeri 12.98 8.8 2 PMID:28827360;PMID:30131334 -1.1.99.40 d-2-hydroxyglutarate saccharomyces cerevisiae 4.0 4.0 1 PMID:26774271 -1.1.99.40 pyruvate saccharomyces cerevisiae 4.9 4.9 1 PMID:26774271 -1.1.99.42 4-pyridoxate mesorhizobium loti 11.0 11.0 1 PMID:18216065 -1.1.99.42 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate mesorhizobium loti 217.0 217.0 1 PMID:19218190 -1.1.99.42 nad+ mesorhizobium loti 0.01 0.01 1 PMID:17868768 -1.1.99.9 pyridoxine arthrobacter sp. 22.0 22.0 1 PMID:3533935 -1.10.3.1 1,2,3-benzenetriol agaricus bisporus 1263.0 1263.0 1 * -1.10.3.1 1-tert-butyl-catechol agaricus bisporus 641.0 641.0 1 PMID:17263494 -1.10.3.1 2,3,4-trihydroxybenzoic acid lablab purpureus 3.05 3.05 1 PMID:17651437 -1.10.3.1 3,4-dihydroxyphenyl acetic acid agaricus bisporus 631.6 582.3 2 * -1.10.3.1 3,4-dihydroxyphenyl acetic acid neurospora crassa 850.0 850.0 1 * -1.10.3.1 3,4-dihydroxyphenyl acetic acid streptomyces glaucescens 142.0 142.0 1 * -1.10.3.1 3,4-dihydroxyphenyl propionic acid agaricus bisporus 553.5 553.5 1 * -1.10.3.1 3,4-dihydroxyphenyl propionic acid streptomyces glaucescens 1830.0 1830.0 1 * -1.10.3.1 3,4-dihydroxyphenylacetic acid lablab purpureus 11.48 11.48 1 PMID:17651437 -1.10.3.1 4-methylcatechol agaricus bisporus 842.0 841.8 2 PMID:17263494 -1.10.3.1 4-methylcatechol lablab purpureus 26.66 26.66 1 PMID:17651437 -1.10.3.1 4-methylcatechol streptomyces glaucescens 2340.0 2340.0 1 * -1.10.3.1 4-tert-butylcatechol lablab purpureus 48.05 48.05 1 PMID:17651437 -1.10.3.1 caffeic acid lycopus europaeus 106.0 106.0 1 PMID:10069382 -1.10.3.1 caffeic acid solanum lycopersicum 20.33 20.33 1 PMID:30858490 -1.10.3.1 catechol agaricus bisporus 878.0 877.8 2 PMID:17263494 -1.10.3.1 catechol lablab purpureus 7.48 7.48 1 PMID:17651437 -1.10.3.1 catechol lycopus europaeus 160.0 160.0 1 PMID:10069382 -1.10.3.1 catechol streptomyces glaucescens 395.0 395.0 1 * -1.10.3.1 chlorogenic acid agaricus bisporus 176.0 155.5 2 PMID:17263494 -1.10.3.1 chlorogenic acid lycopus europaeus 156.0 156.0 1 PMID:10069382 -1.10.3.1 chlorogenic acid streptomyces glaucescens 785.0 785.0 1 * -1.10.3.1 d-2-methyl-3,4-dihydroxyphenylalanine agaricus bisporus 44.3 44.3 1 * -1.10.3.1 d-dopa agaricus bisporus 107.4 107.4 1 * -1.10.3.1 d-dopa bos taurus 0.000338 0.000338 1 PMID:12693934 -1.10.3.1 d-dopa neurospora crassa 340.0 340.0 1 * -1.10.3.1 d-dopa streptomyces glaucescens 184.0 184.0 1 * -1.10.3.1 d-isoproterenol agaricus bisporus 29.8 29.8 1 * -1.10.3.1 dihydrocaffeic acid lycopus europaeus 113.0 113.0 1 PMID:10069382 -1.10.3.1 dopamine agaricus bisporus 439.0 439.0 1 PMID:17263494 -1.10.3.1 dopamine aphonopelma californicum (nom. dub.) 6.0 5.85 2 PMID:18279382 -1.10.3.1 dopamine lablab purpureus 4.9 4.9 1 PMID:17651437 -1.10.3.1 dopamine neurospora crassa 1350.0 1350.0 1 * -1.10.3.1 dopamine scyllarides latus 282.0 282.0 1 PMID:16010551 -1.10.3.1 dopamine solanum lycopersicum 1.99 1.99 1 PMID:30858490 -1.10.3.1 dopamine streptomyces glaucescens 875.0 875.0 1 * -1.10.3.1 l-2-methyl-3,4-dihydroxyphenylalanine agaricus bisporus 44.3 44.3 1 * -1.10.3.1 l-3,4-dihydroxyphenylalanine methyl ester agaricus bisporus 35.5 35.5 1 * -1.10.3.1 l-adrenaline bos taurus 1.48e-06 1.48e-06 1 PMID:12693934 -1.10.3.1 l-dopa agaricus bisporus 107.4 107.4 1 * -1.10.3.1 l-dopa bos taurus 0.000459 0.000459 1 PMID:12693934 -1.10.3.1 l-dopa neurospora crassa 1070.0 1070.0 1 * -1.10.3.1 l-dopa streptomyces glaucescens 1445.0 1445.0 1 * -1.10.3.1 l-isoproterenol agaricus bisporus 29.4 29.4 1 * -1.10.3.1 l-noradrenaline bos taurus 9.12e-08 9.12e-08 1 PMID:12693934 -1.10.3.1 luteolin-7-glycoside lycopus europaeus 22.7 22.7 1 PMID:10069382 -1.10.3.1 myricetin lycopus europaeus 213.0 213.0 1 PMID:10069382 -1.10.3.1 quercetin lycopus europaeus 193.0 193.0 1 PMID:10069382 -1.10.3.1 rosmarinic acid lycopus europaeus 109.0 109.0 1 PMID:10069382 -1.10.3.1 tert-butylcatechol agaricus bisporus 641.8 641.8 1 * -1.10.3.1 tert-butylcatechol streptomyces glaucescens 3320.0 3320.0 1 * -1.10.3.1 verbascosid lycopus europaeus 150.0 150.0 1 PMID:10069382 -1.10.3.15 2-amino-4-methylphenol streptomyces griseus 18.0 18.0 1 PMID:16282322 -1.10.3.15 3,4-dihydroxybenzaldehyde streptomyces griseus 0.8 0.8 1 PMID:16282322 -1.10.3.15 3-amino-4-hydroxybenzaldehyde streptomyces griseus 14.0 14.0 1 PMID:16282322 -1.10.3.15 catechol streptomyces griseus 12.0 12.0 1 PMID:16282322 -1.10.3.15 l-dopa streptomyces griseus 0.066 0.066 1 PMID:16282322 -1.10.3.15 o-aminophenol streptomyces griseus 20.0 20.0 1 PMID:16282322 -1.10.3.2 1-hydroxybenzotriazole basidiomycete pm1 28.8 22.15 2 PMID:31505206 -1.10.3.2 1-hydroxybenzotriazole lentinus tigrinus 2.6 2.6 1 PMID:17013550 -1.10.3.2 1-naphthol uncultured bacterium 3.56 3.56 1 PMID:34054745 -1.10.3.2 2,2'-azino-bis(3-ethyl-benzothiazoline-6-sulfonic acid) bacillus subtilis 322.0 322.0 1 PMID:18307408 -1.10.3.2 2,2'-azino-bis(3-ethyl-benzothiazoline-6-sulfonic acid) melanocarpus albomyces 28.1 28.1 1 PMID:19780817 -1.10.3.2 2,2'-azino-bis(3-ethyl-benzothiazoline-6-sulfonic acid) phoma sp. 10.6 10.6 1 PMID:19455326 -1.10.3.2 2,2'-azino-bis(3-ethyl-benzothiazoline-6-sulfonic acid) shigella dysenteriae 18.2 18.2 1 * -1.10.3.2 2,2'-azino-bis(3-ethyl-benzothiazoline-6-sulfonic acid) trametes hirsuta 197.0 197.0 1 PMID:19221878 -1.10.3.2 2,2'-azino-bis(3-ethyl-benzothiazoline-6-sulfonic acid) trametes sanguinea 59.3 53.95 2 * -1.10.3.2 2,2'-azino-bis(3-ethylbenzathiazoline-6-sulfonate) obba rivulosa 409.0 347.5 2 PMID:17805527 -1.10.3.2 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonate) bacillus licheniformis 83.0 83.0 1 PMID:18330561 -1.10.3.2 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonate) perenniporia fraxinea 208.0 208.0 1 PMID:18467859 -1.10.3.2 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) basidiomycete pm1 240.0 142.2 2 PMID:31505206 -1.10.3.2 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) fomitopsis pinicola 409.0 178.8 4 PMID:34116754 -1.10.3.2 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) geobacillus sp. js12 0.3 0.3 1 PMID:32315700 -1.10.3.2 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) pestalotiopsis sp. kf079 0.696 0.5635 2 PMID:30991752 -1.10.3.2 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) streptomyces griseoflavus 15.0 15.0 2 PMID:35008493 -1.10.3.2 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) thielavia sp. 4.14 4.14 1 PMID:30268749 -1.10.3.2 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) trametes hirsuta 198.29 198.29 1 PMID:33146857 -1.10.3.2 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) uncultured bacterium 34.39 34.39 1 PMID:34054745 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonate) myrioconium sp. 0.29 0.29 1 PMID:17955194 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) bacillus pumilus 291.0 291.0 1 PMID:21266052 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) bacillus sp. (in: firmicutes) 127.0 127.0 1 PMID:20473548 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) cerrena sp. wr1 934.6 934.6 1 PMID:23081836 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) collybia mongolica 1480.0 1480.0 1 PMID:20668399 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) coprinopsis cinerea 4.22 4.22 1 PMID:23073779 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) coprinus comatus 15.93 4.41 4 PMID:23076537 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) fusarium solani 107.1 107.1 1 PMID:20716485 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) ganoderma fornicatum 65.6 65.6 1 * -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) melanocarpus albomyces 109.0 109.0 1 PMID:20056172 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) mycothermus thermophilus 0.14 0.14 1 * -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) pleurotus ostreatus 20.0 20.0 1 PMID:22806800 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) podospora anserina 1372.0 1372.0 1 PMID:23220637 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) shiraia sp. super-h168 7109.0 7109.0 1 * -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) toxicodendron vernicifluum 10.1 10.1 1 PMID:20056172 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) trametes cinnabarina 144.6 91.3 2 PMID:22210206 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) trametes hirsuta 196.0 196.0 1 PMID:20056172 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) trametes polyzona 594.0 594.0 1 PMID:23775771 -1.10.3.2 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) trametes versicolor 130.0 130.0 1 PMID:20056172 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) agrobacterium sp. s5-1 32.8 32.8 1 PMID:26010258 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) bacillus pumilus 377.0 209.6 2 PMID:27771851;PMID:28482039 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) bacillus sp. (in: firmicutes) 309.0 45.8 3 PMID:27059481 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) bacillus tequilensis 67.04 67.04 1 PMID:24871763 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) cerrena sp. 2468.0 2468.0 1 PMID:25356987 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) cerrena unicolor 286.5 286.5 1 PMID:27793681 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) coprinopsis cinerea 32.03 32.03 1 PMID:24178808 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) coprinus comatus 3.485 2.476 2 PMID:24710109 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) coriolopsis trogii 399.0 329.5 2 PMID:25876603 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) cubamyces flavidus 6.45 6.45 1 * -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) daucus carota 0.018534 0.015760999999999997 2 PMID:26626349 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) hexagonia tenuis 2.54 2.54 1 PMID:26040112 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) klebsiella pneumoniae 1.02 1.02 1 * -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) leucaena leucocephala 0.058 0.058 1 * -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) mycetinis scorodonius 72.0 72.0 1 PMID:28376610 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) streptomyces griseorubens 7.7 7.7 1 PMID:25820450 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) streptomyces viridochromogenes 1.9 1.9 1 PMID:25778839 -1.10.3.2 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) tropicoporus linteus 6.85 6.85 1 PMID:25434183 -1.10.3.2 2,2'-azinobis (3-ethylbenzthiazoline-6-sulfonate) thermus thermophilus 24.6 4.05 4 PMID:15999224;PMID:29063287 -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) agaricus blazei 21.0 21.0 1 PMID:15647930 -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) bacillus subtilis 22.4 22.4 1 PMID:16680453 -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) basidiomycota 778.0 778.0 1 * -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) chaetomiaceae 26.0 26.0 1 * -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) cyathus bulleri 204.0 204.0 1 PMID:15941663 -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) fomes sclerodermeus 199.0 190.5 2 * -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) melanocarpus albomyces 78.3 78.3 1 PMID:15347764 -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) pleurotus ostreatus 158300.0 73300.0 3 * -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) pleurotus pulmonarius 1520.0 1520.0 1 PMID:12872309 -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) trametes cinnabarina 272.0 272.0 1 PMID:14600793 -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) trametes sanguinea 68.87 68.87 1 PMID:17186237 -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) trametes sp. 2277.0 1484.5 2 PMID:12664149;PMID:21148825 -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) trametes versicolor 1.3 0.1345 6 PMID:15769520;PMID:16368720 -1.10.3.2 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) trichophyton rubrum 10.3 10.3 1 * -1.10.3.2 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonate) bacillus subtilis 322.0 322.0 1 PMID:17957391 -1.10.3.2 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonate) desulfovibrio sp. a2 0.58 0.58 1 PMID:28749328 -1.10.3.2 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonate) escherichia coli 0.98 0.98 1 PMID:21142169 -1.10.3.2 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonate) thermus thermophilus 0.69 0.47 2 PMID:33535124 -1.10.3.2 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) marinomonas mediterranea 4.5 2.5 3 PMID:27050199 -1.10.3.2 2,2,6,6-tetramethylpiperidin-n-oxide radical lentinus tigrinus 7.8 7.8 1 PMID:17013550 -1.10.3.2 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) haloferax volcanii 10.0 10.0 1 PMID:19966030 -1.10.3.2 2,2-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) aquisalibacillus elongatus 2150.0 2150.0 1 PMID:28161622 -1.10.3.2 2,2-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) carica papaya 0.00403 0.00403 1 PMID:25192855 -1.10.3.2 2,2-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) trametes sp. 549.0 313.5 6 PMID:24877646 -1.10.3.2 2,3-dihydroxybenzoate desulfovibrio sp. a2 0.038 0.038 1 PMID:28749328 -1.10.3.2 2,5-diaminotoluene escherichia coli 19.0 19.0 1 PMID:23337502 -1.10.3.2 2,5-xylidine aquisalibacillus elongatus 284.4 284.4 1 PMID:28161622 -1.10.3.2 2,6-dimethoxyphenol agaricus blazei 15.0 15.0 1 PMID:15647930 -1.10.3.2 2,6-dimethoxyphenol aquisalibacillus elongatus 1009.4 1009.4 1 PMID:28161622 -1.10.3.2 2,6-dimethoxyphenol bacillus licheniformis 8.0 8.0 1 PMID:18330561 -1.10.3.2 2,6-dimethoxyphenol bacillus pumilus 23.2 17.1 2 PMID:21266052;PMID:28482039 -1.10.3.2 2,6-dimethoxyphenol bacillus sp. (in: firmicutes) 3.0 3.0 1 PMID:20473548 -1.10.3.2 2,6-dimethoxyphenol bacillus subtilis 29.0 6.65 3 PMID:16680453;PMID:17957391;PMID:18307408 -1.10.3.2 2,6-dimethoxyphenol bacillus tequilensis 73.15 73.15 1 PMID:24871763 -1.10.3.2 2,6-dimethoxyphenol basidiomycete pm1 45.3 29.25 2 PMID:31505206 -1.10.3.2 2,6-dimethoxyphenol cerrena sp. 703.7 703.7 1 PMID:25356987 -1.10.3.2 2,6-dimethoxyphenol cerrena sp. wr1 109.2 109.2 1 PMID:23081836 -1.10.3.2 2,6-dimethoxyphenol chaetomiaceae 34.0 34.0 1 * -1.10.3.2 2,6-dimethoxyphenol coprinopsis cinerea 2.3 2.3 1 PMID:24178808 -1.10.3.2 2,6-dimethoxyphenol coriolopsis trogii 329.0 189.65 2 PMID:25876603 -1.10.3.2 2,6-dimethoxyphenol cubamyces flavidus 6.45 6.45 1 * -1.10.3.2 2,6-dimethoxyphenol cyathus bulleri 180.0 180.0 1 PMID:15941663 -1.10.3.2 2,6-dimethoxyphenol fomes sclerodermeus 218.0 212.0 2 * -1.10.3.2 2,6-dimethoxyphenol fomitopsis pinicola 155.0 58.4 4 PMID:34116754 -1.10.3.2 2,6-dimethoxyphenol fusarium solani 121.0 121.0 1 PMID:20716485 -1.10.3.2 2,6-dimethoxyphenol ganoderma fornicatum 38.5 38.5 1 * -1.10.3.2 2,6-dimethoxyphenol geobacillus sp. js12 38.81 38.81 1 PMID:32315700 -1.10.3.2 2,6-dimethoxyphenol hexagonia tenuis 2.54 2.54 1 PMID:26040112 -1.10.3.2 2,6-dimethoxyphenol klebsiella pneumoniae 2.93 2.93 1 * -1.10.3.2 2,6-dimethoxyphenol lentinus tigrinus 365.6 191.65 2 PMID:17013550 -1.10.3.2 2,6-dimethoxyphenol marinomonas mediterranea 1.98 1.74 3 PMID:27050199 -1.10.3.2 2,6-dimethoxyphenol melanocarpus albomyces 67.0 38.6 2 PMID:15347764;PMID:19780817 -1.10.3.2 2,6-dimethoxyphenol mycetinis scorodonius 68.0 68.0 1 PMID:28376610 -1.10.3.2 2,6-dimethoxyphenol mycothermus thermophilus 0.35 0.35 1 * -1.10.3.2 2,6-dimethoxyphenol myrioconium sp. 3.18 3.18 1 PMID:17955194 -1.10.3.2 2,6-dimethoxyphenol obba rivulosa 481.0 414.0 2 PMID:17805527 -1.10.3.2 2,6-dimethoxyphenol perenniporia fraxinea 103.0 103.0 1 PMID:18467859 -1.10.3.2 2,6-dimethoxyphenol pestalotiopsis sp. kf079 2.441 1.3094999999999999 2 PMID:30991752 -1.10.3.2 2,6-dimethoxyphenol phoma sp. 4.3 4.3 1 PMID:19455326 -1.10.3.2 2,6-dimethoxyphenol pleurotus ostreatus 23800.0 10004.47 4 * -1.10.3.2 2,6-dimethoxyphenol shiraia sp. super-h168 1476.0 1476.0 1 * -1.10.3.2 2,6-dimethoxyphenol streptomyces griseoflavus 0.35 0.35 2 PMID:35008493 -1.10.3.2 2,6-dimethoxyphenol streptomyces griseorubens 0.058 0.058 1 PMID:25820450 -1.10.3.2 2,6-dimethoxyphenol streptomyces viridochromogenes 34.4 34.4 1 PMID:25778839 -1.10.3.2 2,6-dimethoxyphenol thielavia sp. 3.46 3.46 1 PMID:30268749 -1.10.3.2 2,6-dimethoxyphenol trametes cinnabarina 26.4 21.35 2 PMID:22210206 -1.10.3.2 2,6-dimethoxyphenol trametes hirsuta 50.0 50.0 1 PMID:19221878 -1.10.3.2 2,6-dimethoxyphenol trametes polyzona 38.2 38.2 1 PMID:23775771 -1.10.3.2 2,6-dimethoxyphenol trametes sanguinea 6.91 6.91 1 PMID:17186237 -1.10.3.2 2,6-dimethoxyphenol trametes sp. 189.0 135.0 2 PMID:12664149;PMID:21148825 -1.10.3.2 2,6-dimethoxyphenol trametes versicolor 0.51 0.51 1 PMID:16368720 -1.10.3.2 2,6-dimethoxyphenol tropicoporus linteus 6.85 6.85 1 PMID:25434183 -1.10.3.2 2,6-dimethoxyphenol uncultured bacterium 9.43 9.43 1 PMID:34054745 -1.10.3.2 2,6-dimethylphenol coprinus comatus 1.468 0.8875 2 PMID:24710109 -1.10.3.2 2-dianisidine pleurotus ostreatus 20.7 20.7 1 PMID:22806800 -1.10.3.2 2-dianisidine trametes sanguinea 9.4 7.15 2 * -1.10.3.2 2-methoxyphenol lentinus tigrinus 22.8 22.8 1 PMID:17013550 -1.10.3.2 3-dimethylaminobenzoic acid basidiomycota 368.0 368.0 1 * -1.10.3.2 4-hydroxy-3,5-dimethoxybenzaldehyde azine melanocarpus albomyces 140.0 140.0 1 PMID:20056172 -1.10.3.2 4-hydroxy-3,5-dimethoxybenzaldehyde azine toxicodendron vernicifluum 0.32 0.32 1 PMID:20056172 -1.10.3.2 4-hydroxy-3,5-dimethoxybenzaldehyde azine trametes hirsuta 122.0 122.0 1 PMID:20056172 -1.10.3.2 4-hydroxy-3,5-dimethoxybenzaldehyde azine trametes versicolor 77.0 77.0 1 PMID:20056172 -1.10.3.2 4-hydroxy-3,5-dimethoxybenzaldehyde azine tropicoporus linteus 6.85 6.85 1 PMID:25434183 -1.10.3.2 4-hydroxybenzoic acid basidiomycete pm1 8.6 5.81 2 PMID:31505206 -1.10.3.2 4-hydroxyindole chaetomiaceae 128.0 128.0 1 * -1.10.3.2 4-methoxyphenol lentinus tigrinus 36.3 36.3 1 PMID:17013550 -1.10.3.2 4-methyl catechol lentinus tigrinus 93.9 93.9 1 PMID:17013550 -1.10.3.2 anthraquinonic dye acid blue 62 phoma sp. 32.2 32.2 1 PMID:19455326 -1.10.3.2 bilirubin haloferax volcanii 29.0 29.0 1 PMID:19966030 -1.10.3.2 catechol aquisalibacillus elongatus 412.5 412.5 1 PMID:28161622 -1.10.3.2 catechol carica papaya 0.0165 0.0165 1 PMID:25192855 -1.10.3.2 catechol cerrena sp. 626.0 626.0 1 PMID:25356987 -1.10.3.2 catechol cerrena sp. wr1 115.5 115.5 1 PMID:23081836 -1.10.3.2 catechol chaetomiaceae 46.0 46.0 1 * -1.10.3.2 catechol fusarium solani 44.9 44.9 1 PMID:20716485 -1.10.3.2 catechol lentinus tigrinus 34.4 34.4 1 PMID:17013550 -1.10.3.2 catechol leucaena leucocephala 0.042 0.042 1 * -1.10.3.2 catechol marinomonas mediterranea 4.2 2.18 3 PMID:27050199 -1.10.3.2 catechol melanocarpus albomyces 88.0 88.0 1 PMID:20056172 -1.10.3.2 catechol toxicodendron vernicifluum 2.6 2.6 1 PMID:20056172 -1.10.3.2 catechol trametes hirsuta 202.0 202.0 1 PMID:20056172 -1.10.3.2 catechol trametes polyzona 125.0 125.0 1 PMID:23775771 -1.10.3.2 catechol trametes versicolor 115.0 115.0 1 PMID:20056172 -1.10.3.2 diamond black pv 200 agroathelia rolfsii 80.4 80.4 1 * -1.10.3.2 dopamine melanocarpus albomyces 116.0 116.0 1 PMID:20056172 -1.10.3.2 dopamine toxicodendron vernicifluum 4.4 4.4 1 PMID:20056172 -1.10.3.2 dopamine trametes hirsuta 184.0 184.0 1 PMID:20056172 -1.10.3.2 dopamine trametes versicolor 186.0 186.0 1 PMID:20056172 -1.10.3.2 eugenol trametes hirsuta 428.0 428.0 1 * -1.10.3.2 ferrocenemonocarboxylic acid melanocarpus albomyces 75.0 75.0 1 PMID:20056172 -1.10.3.2 ferrocenemonocarboxylic acid toxicodendron vernicifluum 0.92 0.92 1 PMID:20056172 -1.10.3.2 ferrocenemonocarboxylic acid trametes hirsuta 137.0 137.0 1 PMID:20056172 -1.10.3.2 ferrocenemonocarboxylic acid trametes versicolor 83.0 83.0 1 PMID:20056172 -1.10.3.2 ferrocyanide melanocarpus albomyces 64.0 64.0 1 PMID:20056172 -1.10.3.2 ferrocyanide toxicodendron vernicifluum 0.1 0.1 1 PMID:20056172 -1.10.3.2 ferrocyanide trametes hirsuta 108.0 108.0 1 PMID:20056172 -1.10.3.2 ferrocyanide trametes versicolor 215.0 215.0 1 PMID:20056172 -1.10.3.2 ferulic acid cyathus bulleri 5.2 5.2 1 PMID:15941663 -1.10.3.2 gallic acid aquisalibacillus elongatus 675.0 675.0 1 PMID:28161622 -1.10.3.2 guaiacol agaricus blazei 159.0 159.0 1 PMID:15647930 -1.10.3.2 guaiacol aquisalibacillus elongatus 56.3 56.3 1 PMID:28161622 -1.10.3.2 guaiacol aureobasidium pullulans 2.53 2.53 1 * -1.10.3.2 guaiacol bacillus pumilus 40.0 25.95 2 PMID:27771851;PMID:28482039 -1.10.3.2 guaiacol bacillus tequilensis 62.96 62.96 1 PMID:24871763 -1.10.3.2 guaiacol basidiomycete pm1 10.5 6.675 2 PMID:31505206 -1.10.3.2 guaiacol basidiomycota 42.1 42.1 1 * -1.10.3.2 guaiacol cerrena sp. 128.1 128.1 1 PMID:25356987 -1.10.3.2 guaiacol cerrena sp. wr1 147.9 147.9 1 PMID:23081836 -1.10.3.2 guaiacol chaetomiaceae 6.0 6.0 1 * -1.10.3.2 guaiacol coprinopsis cinerea 0.211 0.211 1 PMID:23073779 -1.10.3.2 guaiacol coprinus comatus 0.418 0.307 2 PMID:24710109 -1.10.3.2 guaiacol coriolopsis trogii 21.1 21.1 1 PMID:25876603 -1.10.3.2 guaiacol cyathus bulleri 95.6 50.55 2 PMID:15941663 -1.10.3.2 guaiacol fomitopsis pinicola 85.1 32.35 4 PMID:34116754 -1.10.3.2 guaiacol fusarium solani 28.4 28.4 1 PMID:20716485 -1.10.3.2 guaiacol ganoderma fornicatum 5.0 5.0 1 * -1.10.3.2 guaiacol geobacillus sp. js12 45.17 45.17 1 PMID:32315700 -1.10.3.2 guaiacol melanocarpus albomyces 31.7 31.7 1 PMID:15347764 -1.10.3.2 guaiacol mycetinis scorodonius 226.0 226.0 1 PMID:28376610 -1.10.3.2 guaiacol obba rivulosa 82.0 76.5 2 PMID:17805527 -1.10.3.2 guaiacol phoma sp. 4.6 4.6 1 PMID:19455326 -1.10.3.2 guaiacol pleurotus ostreatus 3.9 3.9 1 PMID:22806800 -1.10.3.2 guaiacol pleurotus pulmonarius 310.0 310.0 1 PMID:12872309 -1.10.3.2 guaiacol shiraia sp. super-h168 30.44 30.44 1 * -1.10.3.2 guaiacol streptomyces viridochromogenes 8.0 8.0 1 PMID:25778839 -1.10.3.2 guaiacol thermus thermophilus 6.9 6.5 2 PMID:32056499;PMID:33588000 -1.10.3.2 guaiacol trametes hirsuta 424.0 252.1 2 PMID:33146857 -1.10.3.2 guaiacol trametes polyzona 92.2 92.2 1 PMID:23775771 -1.10.3.2 guaiacol trametes sanguinea 3.0 2.525 2 * -1.10.3.2 guaiacol trametes sp. 140.0 104.5 2 PMID:12664149;PMID:21148825 -1.10.3.2 guaiacol uncultured bacterium 1.34 1.34 1 PMID:34054745 -1.10.3.2 homovanillic acid trametes hirsuta 408.0 408.0 1 * -1.10.3.2 hydroquinone aquisalibacillus elongatus 443.8 443.8 1 PMID:28161622 -1.10.3.2 hydroquinone carica papaya 0.051 0.051 1 PMID:25192855 -1.10.3.2 hydroquinone chaetomiaceae 55.0 55.0 1 * -1.10.3.2 hydroquinone leucaena leucocephala 0.23 0.23 1 * -1.10.3.2 hydroquinone trametes hirsuta 455.0 455.0 1 * -1.10.3.2 k4(fecn6) bacillus subtilis 54.5 54.5 1 PMID:16680453 -1.10.3.2 k4[fe(cn)6] streptomyces griseoflavus 38.0 38.0 1 PMID:35008493 -1.10.3.2 k4[fe(cn)6] streptomyces viridochromogenes 0.2 0.2 1 PMID:25778839 -1.10.3.2 k4[fe(cn)]6 trametes hirsuta 404.0 404.0 1 * -1.10.3.2 k4fe(cn)6 bacillus subtilis 529.0 529.0 1 PMID:17957391 -1.10.3.2 l-dopa aquisalibacillus elongatus 318.8 318.8 1 PMID:28161622 -1.10.3.2 l-dopa trametes polyzona 83.2 83.2 1 PMID:23775771 -1.10.3.2 l-tyrosine aquisalibacillus elongatus 462.5 462.5 1 PMID:28161622 -1.10.3.2 methyl syringate trichophyton rubrum 5.5 5.5 1 * -1.10.3.2 n,n-dimethyl-1,4-phenylenediamine chaetomiaceae 18.0 18.0 1 * -1.10.3.2 n,n-dimethyl-4-phenylenediamine toxicodendron vernicifluum 443.0 314.5 2 PMID:16959319 -1.10.3.2 n,n-dimethyl-p-phenylenediamine basidiomycete pm1 938.0 523.3 2 PMID:31505206 -1.10.3.2 n-acetyldopamine manduca sexta 4.83 1.67 3 PMID:19576986 -1.10.3.2 n-beta-alanyldopamine manduca sexta 3.33 3.165 2 PMID:19576986 -1.10.3.2 n-hydroxyacetanilide trichophyton rubrum 18.3 18.3 1 * -1.10.3.2 o-benzenediol pleurotus ostreatus 21.98 14.99 2 * -1.10.3.2 o-benzenediol trametes hirsuta 403.0 403.0 1 * -1.10.3.2 o-dianisidine pestalotiopsis sp. kf079 0.748 0.4025 2 PMID:30991752 -1.10.3.2 phenol trametes hirsuta 38.0 38.0 1 * -1.10.3.2 pyrogallol aquisalibacillus elongatus 1231.3 1231.3 1 PMID:28161622 -1.10.3.2 pyrogallol chaetomiaceae 10.0 10.0 1 * -1.10.3.2 sinapic acid trametes cinnabarina 52.8 37.2 2 PMID:22210206 -1.10.3.2 sinapic acid trametes hirsuta 578.0 578.0 1 * -1.10.3.2 syringaldazine agaricus blazei 5.0 5.0 1 PMID:15647930 -1.10.3.2 syringaldazine aquisalibacillus elongatus 918.8 918.8 1 PMID:28161622 -1.10.3.2 syringaldazine bacillus licheniformis 100.0 100.0 1 PMID:18330561 -1.10.3.2 syringaldazine bacillus pumilus 66.0 35.45 2 PMID:21266052 -1.10.3.2 syringaldazine bacillus sp. (in: firmicutes) 51.0 24.0 3 PMID:20473548;PMID:27059481 -1.10.3.2 syringaldazine bacillus subtilis 80.0 49.2 4 PMID:16680453;PMID:17957391;PMID:18031270;PMID:18307408 -1.10.3.2 syringaldazine chaetomiaceae 4.0 4.0 1 * -1.10.3.2 syringaldazine coprinus comatus 44.71 38.335 2 PMID:24710109 -1.10.3.2 syringaldazine coriolopsis trogii 35.9 35.9 1 PMID:25876603 -1.10.3.2 syringaldazine cubamyces flavidus 6.45 6.45 1 * -1.10.3.2 syringaldazine haloferax volcanii 22.0 22.0 1 PMID:19966030 -1.10.3.2 syringaldazine hexagonia tenuis 2.54 2.54 1 PMID:26040112 -1.10.3.2 syringaldazine melanocarpus albomyces 92.0 66.08500000000001 2 PMID:15347764;PMID:19780817 -1.10.3.2 syringaldazine myrioconium sp. 2.96 2.96 1 PMID:17955194 -1.10.3.2 syringaldazine obba rivulosa 282.0 203.0 2 PMID:17805527 -1.10.3.2 syringaldazine pestalotiopsis sp. kf079 0.573 0.469 2 PMID:30991752 -1.10.3.2 syringaldazine phoma sp. 1.5 1.5 1 PMID:19455326 -1.10.3.2 syringaldazine pleurotus ostreatus 11670.0 2830.0 3 * -1.10.3.2 syringaldazine pleurotus pulmonarius 654.0 654.0 1 PMID:12872309 -1.10.3.2 syringaldazine podospora anserina 1.29 1.29 1 PMID:23220637 -1.10.3.2 syringaldazine shiraia sp. super-h168 938.1 938.1 1 * -1.10.3.2 syringaldazine streptomyces griseorubens 0.337 0.337 1 PMID:25820450 -1.10.3.2 syringaldazine thermus thermophilus 10.3 5.9 4 PMID:15999224;PMID:29063287 -1.10.3.2 syringaldazine trametes sanguinea 65.8 45.71 4 PMID:17186237 -1.10.3.2 syringaldazine trametes sp. 600.0 246.0 7 PMID:21148825;PMID:24877646 -1.10.3.2 syringic acid basidiomycota 10.1 10.1 1 * -1.10.3.2 tannic acid aquisalibacillus elongatus 1471.9 1471.9 1 PMID:28161622 -1.10.3.2 vanillic acid trametes hirsuta 102.0 102.0 1 * -1.10.3.2 vanillic alcohol trametes hirsuta 352.0 352.0 1 * -1.10.3.2 violuric acid lentinus tigrinus 8.4 8.4 1 PMID:17013550 -1.10.3.2 violuric acid trichophyton rubrum 10.0 10.0 1 * -1.10.3.3 5,6-ene-l-ascorbate cucurbita pepo medullosa 639.0 639.0 1 PMID:7945293 -1.10.3.3 5,6-isopropylidene-l-ascorbate cucurbita pepo medullosa 623.0 623.0 1 PMID:7945293 -1.10.3.3 5-methyl-5-o-(alpha-d-glucopyranosyl)-d-erythroascorbic acid pleurotus ostreatus 0.55 0.55 1 PMID:19412602 -1.10.3.3 5-methyl-5-o-(alpha-d-xylopyranosyl)-d-erythroascorbic acid pleurotus ostreatus 0.24 0.24 1 PMID:19412602 -1.10.3.3 5-o-(alpha-d-glucopyranosyl)-d-erythroascorbic acid pleurotus ostreatus 0.6 0.6 1 PMID:19412602 -1.10.3.3 5-o-(alpha-d-xylopyranosyl)-d-erythroascorbic acid pleurotus ostreatus 1.29 1.29 1 PMID:19412602 -1.10.3.3 6-amino-l-ascorbate cucurbita pepo medullosa 546.0 546.0 1 PMID:7945293 -1.10.3.3 6-bromo-l-ascorbate cucurbita pepo medullosa 702.0 702.0 1 PMID:7945293 -1.10.3.3 6-deoxy-l-ascorbate cucurbita pepo medullosa 969.0 969.0 1 PMID:7945293 -1.10.3.3 6-o-phenyl-l-ascorbate cucurbita pepo medullosa 473.0 473.0 1 PMID:7945293 -1.10.3.3 6-s-phenyl-l-ascorbate cucurbita pepo medullosa 526.0 526.0 1 PMID:7945293 -1.10.3.3 d-erythroascorbic acid pleurotus ostreatus 1.12 1.12 1 PMID:19412602 -1.10.3.3 d-isoascorbate cucurbita pepo medullosa 804.0 804.0 1 PMID:7945293 -1.10.3.3 l-ascorbate acremonium 3110.0 3110.0 1 * -1.10.3.3 l-ascorbate cucurbita pepo condensa 10800.0 7485.0 2 * -1.10.3.3 l-ascorbate cucurbita pepo medullosa 682.0 344.8 2 PMID:2604732;PMID:7945293 -1.10.3.3 l-ascorbate homo sapiens 4.54 4.54 1 * -1.10.3.3 l-ascorbic acid pleurotus ostreatus 0.66 0.66 1 PMID:19412602 -1.10.3.3 o2 acremonium 1130.0 1130.0 1 * -1.10.3.4 2-amino-4-methylphenol streptomyces griseus 18.0 18.0 1 PMID:16282322 -1.10.3.4 3,4-dihydroxybenzaldehyde streptomyces griseus 0.8 0.8 1 PMID:16282322 -1.10.3.4 3-amino-4-hydroxybenzaldehyde streptomyces griseus 14.0 14.0 1 PMID:16282322 -1.10.3.4 catechol streptomyces griseus 12.0 12.0 1 PMID:16282322 -1.10.3.4 l-dopa streptomyces griseus 0.066 0.066 1 PMID:16282322 -1.10.3.4 o-aminophenol streptomyces griseus 20.0 20.0 1 PMID:16282322 -1.10.3.9 plastoquinol helianthus annuus 0.054 0.054 1 PMID:25800682 -1.10.5.1 2,6-dichlorophenolindophenol homo sapiens 91.8 69.235 2 PMID:9367528 -1.10.5.1 3-(4,5-dimethylthiazaol-2-yl)-2,5-diphenyltetrazolium homo sapiens 11.0 11.0 1 PMID:9367528 -1.10.5.1 5-(aziridin-1-yl)-2,4-dinitrobenzamide homo sapiens 6.0 6.0 1 PMID:16129418 -1.10.5.1 cb 1954 homo sapiens 6.0 6.0 1 PMID:9367528 -1.10.5.1 dihydronicotinamide riboside homo sapiens 43.33 43.33 1 PMID:9367528 -1.10.5.1 menadione/3-(4,5-dimethylthiazaol-2-yl)-2,5-diphenyltetrazolium homo sapiens 38.33 38.33 1 PMID:9367528 -1.10.5.1 methyl red homo sapiens 3.83 3.83 1 PMID:9367528 -1.10.5.1 nadh homo sapiens 2.6 2.6 1 PMID:9367528 -1.11.1.1 h2o2 enterococcus faecalis 66.7 66.7 1 PMID:199166 -1.11.1.1 nadh enterococcus faecalis 83.3 1.17 3 PMID:10956025;PMID:13416259;PMID:7819235 -1.11.1.10 (r)-limonene leptoxyphium fumago 18.7 11.45 4 * -1.11.1.10 2,3,5,6-tetrachloroaniline leptoxyphium fumago 35.95 35.95 1 PMID:18439646 -1.11.1.10 2,3,5,6-tetrachlorophenol leptoxyphium fumago 60.8 60.8 1 PMID:18439646 -1.11.1.10 2,4,6-trichlorophenol leptoxyphium fumago 11.28 11.28 1 * -1.11.1.10 4,6-dimethyldibenzothiophene leptoxyphium fumago 661.1 431.35 4 PMID:15850562 -1.11.1.10 anthracene leptoxyphium fumago 8.0 7.6 2 PMID:18823932 -1.11.1.10 beta-estradiol leptoxyphium fumago 420.0 226.5 2 PMID:34000929 -1.11.1.10 chlorite leptoxyphium fumago 70000.0 70000.0 1 PMID:7240190 -1.11.1.10 equiline leptoxyphium fumago 1970.0 1950.0 2 PMID:34000929 -1.11.1.10 estrone leptoxyphium fumago 330.0 225.0 2 PMID:34000929 -1.11.1.10 monochlorodimedone musa x paradisiaca 1.64 1.64 1 * -1.11.1.10 naphthalene leptoxyphium fumago 4.5 4.05 2 PMID:18823932 -1.11.1.10 orange g leptoxyphium fumago 911.0 825.5 2 PMID:26926259 -1.11.1.10 pentachlorophenol leptoxyphium fumago 46.97 46.97 1 PMID:18439646 -1.11.1.10 pyrene leptoxyphium fumago 56.6 51.3 2 PMID:18823932 -1.11.1.10 pyrogallol musa x paradisiaca 26.56 26.56 1 * -1.11.1.10 styrene leptoxyphium fumago 30.9 14.5 6 * -1.11.1.11 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) panicum virgatum 0.4 0.4 1 PMID:23809633 -1.11.1.11 ascorbate chlorella vulgaris 696.0 696.0 1 PMID:9672748 -1.11.1.11 ascorbate leishmania major 0.53 0.53 1 PMID:18342641 -1.11.1.11 ascorbate saccharomyces cerevisiae 0.2 0.2 1 PMID:18771292 -1.11.1.11 cytochrome c leishmania major 1.83 1.83 1 PMID:18342641 -1.11.1.11 guaiacol lathyrus oleraceus 66.0 66.0 1 PMID:12084058 -1.11.1.11 guaiacol leishmania major 2.5 2.5 1 PMID:18342641 -1.11.1.11 h2o2 citrus x limon 84.5 84.5 1 * -1.11.1.11 h2o2 euglena gracilis 577.0 577.0 1 PMID:20015051 -1.11.1.11 h2o2 galdieria partita 2190.0 2190.0 1 PMID:18167143 -1.11.1.11 h2o2 gossypium hirsutum 46.71 46.71 1 PMID:17635221 -1.11.1.11 h2o2 musa x paradisiaca 27.24 27.24 1 PMID:30408454 -1.11.1.11 h2o2 nicotiana tabacum 1800.0 1800.0 1 PMID:18167143;PMID:18539135 -1.11.1.11 h2o2 populus tomentosa 29.7 15.865 2 PMID:17899442 -1.11.1.11 l-ascorbate citrus x limon 71.5 71.5 1 * -1.11.1.11 l-ascorbate euglena gracilis 754.0 754.0 1 PMID:20015051 -1.11.1.11 l-ascorbate galdieria partita 1980.0 1980.0 1 PMID:18167143 -1.11.1.11 l-ascorbate gossypium hirsutum 260.0 260.0 1 PMID:17635221 -1.11.1.11 l-ascorbate lathyrus oleraceus 248.0 203.5 2 PMID:12084058;PMID:15584761 -1.11.1.11 l-ascorbate musa x paradisiaca 40.42 40.42 1 PMID:30408454 -1.11.1.11 l-ascorbate nicotiana tabacum 2510.0 2510.0 1 PMID:18167143;PMID:18539135 -1.11.1.11 l-ascorbate pallavicinia lyellii 760.0 760.0 1 PMID:20619666 -1.11.1.11 l-ascorbate panicum virgatum 161.0 161.0 1 PMID:23809633 -1.11.1.11 l-ascorbate populus tomentosa 49.6 25.67 2 PMID:17899442 -1.11.1.12 (beta-(13-hydroperoxy-cis-9,trans-11-octadecadienoyl)-gamma-palmitoyl)-l-alpha-phosphatidylcholine homo sapiens 91.0 91.0 1 PMID:7851631 -1.11.1.12 h2o2 homo sapiens 20.6 20.6 1 PMID:29883798 -1.11.1.12 phosphatidylcholine hydroperoxide homo sapiens 9.2 9.2 1 PMID:29883798 -1.11.1.12 tert-butyl hydroperoxide homo sapiens 5.1 5.1 1 PMID:29883798 -1.11.1.13 2,2'-azino-bis(3-ethyl-benzothiazoline-6-sulfonic acid) schizophyllum sp. 87.1 87.1 1 * -1.11.1.13 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) irpex lacteus 245.0 245.0 1 PMID:30019324 -1.11.1.13 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) lentinus tigrinus 20.2 20.2 1 PMID:19578878 -1.11.1.13 2,2'-azinobis(3-ethylbenzthiazoline)-6-sulfonic acid lentinus tigrinus 20.2 11.035 2 PMID:19578878 -1.11.1.13 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) mn2+ lentinus tigrinus 1.87 1.87 1 PMID:19578878 -1.11.1.13 2,2-azino-di-3-ethylbenzothiazoline-6-sulfonate bjerkandera adusta 139.0 129.5 2 PMID:12070683 -1.11.1.13 2,6-dimethoxyphenol bjerkandera adusta 320.0 195.0 2 PMID:12070683 -1.11.1.13 2,6-dimethoxyphenol irpex lacteus 989.0 80.1 5 PMID:30019324;PMID:31226373 -1.11.1.13 2,6-dimethoxyphenol lentinus tigrinus 26.26 15.965 2 PMID:19578878 -1.11.1.13 2,6-dimethoxyphenol phlebiopsis flavidoalba 3.98 3.98 1 PMID:12437216 -1.11.1.13 2,6-dimethoxyphenol pleurotus ostreatus 200.0 200.0 1 PMID:10729203 -1.11.1.13 2,6-dimethoxyphenol schizophyllum sp. 69.0 69.0 1 * -1.11.1.13 ferrocyanide phanerodontia chrysosporium 4.0 4.0 1 PMID:9100022 -1.11.1.13 guaiacol bjerkandera adusta 31.7 23.1 2 PMID:12070683 -1.11.1.13 guaiacol irpex lacteus 184.0 20.54 5 PMID:30019324;PMID:31226373 -1.11.1.13 guaiacol lentinus tigrinus 8.92 4.83 2 PMID:19578878 -1.11.1.13 guaiacol phanerodontia chrysosporium 56.0 53.0 3 PMID:1592808 -1.11.1.13 guaiacol schizophyllum sp. 17.3 17.3 1 * -1.11.1.13 h2o2 bjerkandera adusta 225.0 225.0 1 PMID:12070683 -1.11.1.13 h2o2 irpex lacteus 879.0 879.0 1 PMID:30019324 -1.11.1.13 h2o2 lentinus tigrinus 121.0 121.0 1 PMID:19578878 -1.11.1.13 h2o2 phanerodontia chrysosporium 252.0 237.0 3 PMID:11106414;PMID:14524699 -1.11.1.13 h2o2 pleurotus ostreatus 230.0 165.0 2 PMID:10729203 -1.11.1.13 h2o2 schizophyllum sp. 373.0 373.0 1 * -1.11.1.13 h2o2 trichophyton rubrum 272.4 272.4 1 * -1.11.1.13 mn(ii) gelatoporia subvermispora 83.0 9.1 3 PMID:25788979;PMID:29305178 -1.11.1.13 mn(ii) irpex lacteus 369.0 369.0 1 PMID:30019324 -1.11.1.13 mn(ii) musa x paradisiaca 6.7 6.7 1 PMID:22435143 -1.11.1.13 mn(iii)-tartrate phanerodontia chrysosporium 98.3 98.3 1 PMID:2306104 -1.11.1.13 mn2+ bjerkandera adusta 150.0 150.0 1 PMID:12070683 -1.11.1.13 mn2+ deuteromycotina sp. 161.0 161.0 1 PMID:8899997 -1.11.1.13 mn2+ lentinus tigrinus 242.4 242.4 1 PMID:19578878 -1.11.1.13 mn2+ phanerodontia chrysosporium 290.0 237.0 4 PMID:10835231;PMID:11106414;PMID:8899997;PMID:9100022 -1.11.1.13 mn2+ phlebiopsis flavidoalba 0.22 0.22 1 PMID:12437216 -1.11.1.13 mn2+ pleurotus ostreatus 230.0 165.0 2 PMID:10729203 -1.11.1.13 mn2+ schizophyllum sp. 479.7 479.7 1 * -1.11.1.13 mn2+ trichophyton rubrum 304.8 304.8 1 * -1.11.1.13 mn3+-tartrate phanerodontia chrysosporium 118.0 118.0 1 PMID:2306104 -1.11.1.13 phenol red phanerodontia chrysosporium 66.0 41.0 3 PMID:1592808 -1.11.1.13 pyrogallol lentinus tigrinus 20.95 15.465 2 PMID:19578878 -1.11.1.13 reactive black 5 irpex lacteus 0.06 0.06 1 PMID:30019324 -1.11.1.13 reactive blue 19 irpex lacteus 7.3 7.3 1 PMID:30019324 -1.11.1.13 vanillylacetone phanerodontia chrysosporium 97.0 90.3 3 PMID:1592808 -1.11.1.13 veratryl alcohol bjerkandera adusta 39.5 22.415 2 PMID:12070683 -1.11.1.13 veratryl alcohol lentinus tigrinus 0.45 0.45 1 PMID:19578878 -1.11.1.14 2,4-dichlorophenol phanerodontia chrysosporium 37.2 37.150000000000006 2 PMID:17961781;PMID:18514942 -1.11.1.14 2,4-dichlorophenol streptomyces griseosporeus 0.06 0.06 1 PMID:25478960 -1.11.1.14 h2o2 phanerodontia chrysosporium 10.83 10.83 1 PMID:17961781;PMID:18514942 -1.11.1.14 h2o2 trametes sanguinea 2.13 2.13 1 * -1.11.1.14 methylene blue bjerkandera adusta 0.18 0.18 1 PMID:22586704 -1.11.1.14 o-dianisidine streptomyces griseosporeus 1.16 1.16 1 PMID:25478960 -1.11.1.14 veratryl alcohol agaricus bisporus 0.12 0.12 1 PMID:28912833 -1.11.1.14 veratryl alcohol bjerkandera sp. 0.185 0.11585 2 PMID:9498823;PMID:9624124 -1.11.1.14 veratryl alcohol lenzites betulinus 2.3 2.3 1 PMID:23330392 -1.11.1.14 veratryl alcohol loweporus lividus 2.5 2.5 1 * -1.11.1.14 veratryl alcohol phanerodontia chrysosporium 13.72 13.72 1 PMID:28912833 -1.11.1.14 veratryl alcohol trametes sanguinea 2.13 2.13 1 * -1.11.1.14 veratryl alcohol trametopsis cervina 17.7 17.0 2 PMID:19505579 -1.11.1.16 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) bjerkandera fumosa 6.2 4.485 2 PMID:23199738 -1.11.1.16 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) bjerkandera sp. 1.3 1.3 1 PMID:9624124 -1.11.1.16 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) pleurotus eryngii 220.0 97.05 6 PMID:18201105;PMID:21980920;PMID:22566208;PMID:23071108 -1.11.1.16 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) pleurotus sapidus 12300.0 12300.0 1 * -1.11.1.16 2,6-dimethoxyphenol bjerkandera fumosa 30.0 20.3 2 PMID:23199738 -1.11.1.16 2,6-dimethoxyphenol bjerkandera sp. 2.3 2.3 1 PMID:9624124 -1.11.1.16 2,6-dimethoxyphenol pleurotus eryngii 98.0 63.9 4 PMID:21980920;PMID:23071108 -1.11.1.16 2,7-diaminofluorene bjerkandera fumosa 0.83 0.51 2 PMID:23199738 -1.11.1.16 2-methylanthracene bjerkandera adusta 2.4 2.4 1 PMID:14735217 -1.11.1.16 4-hydroquinone pleurotus eryngii 35.1 22.700000000000003 2 PMID:23071108 -1.11.1.16 beta-carotene pleurotus sapidus 1000.0 1000.0 1 * -1.11.1.16 catechol pleurotus eryngii 185.0 185.0 1 PMID:23071108 -1.11.1.16 fulvic acid bjerkandera adusta 0.045 0.0315 2 PMID:24631722 -1.11.1.16 guaiacol pleurotus eryngii 22.7 22.7 1 PMID:23071108 -1.11.1.16 h2o2 bjerkandera sp. 75.0 75.0 1 PMID:9624124 -1.11.1.16 h2o2 pleurotus eryngii 135.0 135.0 1 PMID:21980920 -1.11.1.16 h2o2 pleurotus ostreatus 0.6 0.6 1 PMID:27129968 -1.11.1.16 h2o2 rhodococcus jostii 3.2 3.2 1 PMID:22308037 -1.11.1.16 humic acid bjerkandera adusta 0.021 0.0205 2 PMID:24631722 -1.11.1.16 manganese(ii)-substituted polyoxometalate pleurotus eryngii 47.0 47.0 1 PMID:20236822 -1.11.1.16 methoxyhydroquinone pleurotus eryngii 19.0 17.0 3 PMID:10187820;PMID:10508113 -1.11.1.16 methylene blue bjerkandera adusta 2.92 1.55 2 PMID:22586704 -1.11.1.16 mn2+ bjerkandera fumosa 3.9 3.9 1 PMID:23199738 -1.11.1.16 mn2+ bjerkandera sp. 59.0 59.0 1 PMID:9624124 -1.11.1.16 mn2+ pleurotus eryngii 298.0 110.0 9 PMID:10187820;PMID:10508113;PMID:16246366;PMID:19158088;PMID:21980920;PMID:22566208 -1.11.1.16 mn2+ pleurotus ostreatus 6.2 6.2 1 PMID:27129968 -1.11.1.16 orange ii pleurotus ostreatus 0.83 0.83 1 PMID:27129968 -1.11.1.16 p-dimethoxybenzene pleurotus eryngii 4.0 4.0 1 PMID:10187820 -1.11.1.16 reactive black 5 bjerkandera adusta 4.8 4.8 1 * -1.11.1.16 reactive black 5 pleurotus eryngii 11.8 5.25 8 PMID:10187820;PMID:16246366;PMID:18201105;PMID:19158088;PMID:21980920;PMID:22566208 -1.11.1.16 reactive black 5 pleurotus ostreatus 54.0 54.0 1 PMID:27129968 -1.11.1.16 reactive blue 38 bjerkandera adusta 19.8 19.8 1 * -1.11.1.16 reactive blue 72 bjerkandera adusta 10.0 10.0 1 * -1.11.1.16 reactive violet 5 bjerkandera adusta 16.9 16.9 1 * -1.11.1.16 syringaldazine bjerkandera fumosa 6.1 3.1599999999999997 2 PMID:23199738 -1.11.1.16 syringol pleurotus eryngii 6.0 4.5 2 PMID:10187820 -1.11.1.16 syringol pleurotus sapidus 54500.0 54500.0 1 * -1.11.1.16 veratryl alcohol bjerkandera fumosa 26.8 16.94 2 PMID:23199738 -1.11.1.16 veratryl alcohol bjerkandera sp. 2.8 2.0999999999999996 2 PMID:9624124 -1.11.1.16 veratryl alcohol pleurotus eryngii 13.0 8.75 6 PMID:10187820;PMID:10508113;PMID:16246366;PMID:18201105;PMID:19158088;PMID:22566208 -1.11.1.16 veratryl alcohol pleurotus sapidus 1600.0 1600.0 1 * -1.11.1.18 beta-estradiol leptoxyphium fumago 420.0 226.5 2 PMID:34000929 -1.11.1.18 equiline leptoxyphium fumago 1970.0 1950.0 2 PMID:34000929 -1.11.1.18 estrone leptoxyphium fumago 330.0 225.0 2 PMID:34000929 -1.11.1.19 1-amino-4-methylamino-2-sodium anthraquinone sulfonate geotrichum candidum 270.0 270.0 1 PMID:10049859 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) amycolatopsis sp. 87.0 87.0 1 PMID:25743546 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) amycolatopsis sp. atcc 39116 30.0 30.0 1 PMID:33807844 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) auricularia auricula-judae 654.0 273.5 6 PMID:19756587;PMID:25153532;PMID:25495127;PMID:27106285;PMID:33807844 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) basidiomycota sp. 5.4 5.4 1 PMID:33369202 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) bjerkandera adusta 0.96 0.96 1 PMID:27106285 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) dictyostelium discoideum 89.9 89.9 1 PMID:34200865 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) irpex lacteus 790.0 224.0 4 PMID:23666335;PMID:33922393;PMID:34059116 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) mycetinis scorodonius 0.02 0.02 1 PMID:27106285 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) physeter macrocephalus 76.8 76.8 1 PMID:35008837 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) pleurotus sapidus 375.0 190.9 2 PMID:28831735;PMID:32230972 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) pseudomonas putida 23.0 23.0 1 * -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) streptomyces avermitilis 2.8 2.005 2 PMID:28089379;PMID:34445389 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) streptomyces lividans 1.1 1.1 1 PMID:30945782 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) thermomonospora curvata 260.0 156.5 2 PMID:26205819;PMID:33807844 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) vibrio cholerae 500.0 500.0 1 PMID:26431465 -1.11.1.19 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) xylaria grammica 12.0 12.0 1 PMID:34572604 -1.11.1.19 2,4-dichlorophenol bjerkandera adusta 0.101 0.101 2 PMID:28813685 -1.11.1.19 2,4-dichlorophenol streptomyces griseosporeus 0.0635 0.0635 1 PMID:25478960 -1.11.1.19 2,6-dimethoxyphenol amycolatopsis sp. atcc 39116 94.0 94.0 1 PMID:33807844 -1.11.1.19 2,6-dimethoxyphenol auricularia auricula-judae 420.0 120.0 5 PMID:19756587;PMID:25153532;PMID:25495127;PMID:33807844 -1.11.1.19 2,6-dimethoxyphenol bacillus subtilis 0.07 0.07 1 PMID:34687768 -1.11.1.19 2,6-dimethoxyphenol bjerkandera adusta 0.207 0.207 1 PMID:28813685 -1.11.1.19 2,6-dimethoxyphenol irpex lacteus 94.5 70.9 4 PMID:23666335;PMID:33922393;PMID:34059116 -1.11.1.19 2,6-dimethoxyphenol pleurotus sapidus 60.0 60.0 1 PMID:28831735 -1.11.1.19 2,6-dimethoxyphenol pseudomonas putida 0.05 0.05 1 * -1.11.1.19 2,6-dimethoxyphenol streptomyces avermitilis 0.23 0.1635 2 PMID:28089379;PMID:34445389 -1.11.1.19 2,6-dimethoxyphenol thermomonospora curvata 2.7 2.7 1 PMID:33807844 -1.11.1.19 2,6-dimethoxyphenol xylaria grammica 29.0 29.0 1 PMID:34572604 -1.11.1.19 acid blue 324 streptomyces avermitilis 0.79 0.785 2 PMID:28089379;PMID:34445389 -1.11.1.19 catechol thermomonospora curvata 24.0 24.0 1 PMID:26205819 -1.11.1.19 direct blue 71 basidiomycota sp. 0.2 0.2 1 PMID:33369202 -1.11.1.19 direct red 80 basidiomycota sp. 0.04 0.04 1 PMID:33369202 -1.11.1.19 gallic acid pleurotus ostreatus 15.22 15.22 1 PMID:33428421 -1.11.1.19 guaiacol bacillus subtilis 0.07 0.07 1 PMID:34687768 -1.11.1.19 guaiacol physeter macrocephalus 11.0 11.0 1 PMID:35008837 -1.11.1.19 guaiacol pleurotus sapidus 74.0 74.0 1 PMID:28831735 -1.11.1.19 guaiacol thermomonospora curvata 0.33 0.33 1 PMID:26205819 -1.11.1.19 guaiacol vibrio cholerae 0.027 0.027 1 PMID:26431465 -1.11.1.19 guaiacylglycerol-beta-guaiacyl ether amycolatopsis sp. atcc 39116 12.0 12.0 1 PMID:33807844 -1.11.1.19 guaiacylglycerol-beta-guaiacyl ether thermomonospora curvata 1.1 1.1 1 PMID:33807844 -1.11.1.19 h2o2 amycolatopsis sp. atcc 39116 46.0 46.0 1 PMID:33807844 -1.11.1.19 h2o2 anabaena sp. 384.0 384.0 1 PMID:19801472 -1.11.1.19 h2o2 auricularia auricula-judae 268.0 238.0 3 PMID:19756587;PMID:33807844 -1.11.1.19 h2o2 basidiomycota sp. 5.4 5.4 1 PMID:33369202 -1.11.1.19 h2o2 dictyostelium discoideum 93.65 93.65 1 PMID:34200865 -1.11.1.19 h2o2 geotrichum candidum 270.0 265.0 2 PMID:10049859 -1.11.1.19 h2o2 irpex lacteus 1025.0 419.0 4 PMID:23666335;PMID:33922393;PMID:34059116 -1.11.1.19 h2o2 physeter macrocephalus 40.6 40.6 1 PMID:35008837 -1.11.1.19 h2o2 pleurotus ostreatus 118.43 118.43 1 PMID:33428421 -1.11.1.19 h2o2 pseudomonas putida 23.0 23.0 1 * -1.11.1.19 h2o2 thermobifida fusca yx 9.0 9.0 1 PMID:19967355 -1.11.1.19 h2o2 thermomonospora curvata 280.0 43.0 4 PMID:26205819;PMID:33807844 -1.11.1.19 hydroquinone thermomonospora curvata 31.0 31.0 1 PMID:26205819 -1.11.1.19 malachite green bacillus subtilis 0.0456 0.0456 1 PMID:32971035 -1.11.1.19 methyl violet bacillus subtilis 0.022 0.022 1 PMID:32971035 -1.11.1.19 mn2+ amycolatopsis sp. 24.0 24.0 1 PMID:25743546 -1.11.1.19 mn2+ amycolatopsis sp. atcc 39116 42.0 42.0 1 PMID:33807844 -1.11.1.19 mn2+ basidiomycota sp. 0.5 0.5 1 PMID:33369202 -1.11.1.19 mn2+ irpex lacteus 1.8 1.5 2 PMID:33922393 -1.11.1.19 mn2+ pleurotus sapidus 7.2 7.2 1 PMID:32230972 -1.11.1.19 mn2+ xylaria grammica 0.4 0.4 1 PMID:34572604 -1.11.1.19 o-dianisidine streptomyces griseosporeus 1.17 1.17 1 PMID:25478960 -1.11.1.19 pyrogallol dictyostelium discoideum 7.9 7.9 1 PMID:34200865 -1.11.1.19 reactive black 5 auricularia auricula-judae 10.6 3.0 3 PMID:19756587;PMID:25153532 -1.11.1.19 reactive black 5 bacillus subtilis 0.015 0.015 1 PMID:32971035 -1.11.1.19 reactive black 5 basidiomycota sp. 0.58 0.58 1 PMID:33369202 -1.11.1.19 reactive black 5 irpex lacteus 12.9 11.9 3 PMID:23666335;PMID:33922393 -1.11.1.19 reactive blue 19 amycolatopsis sp. atcc 39116 26.0 26.0 1 PMID:33807844 -1.11.1.19 reactive blue 19 auricularia auricula-judae 422.0 224.0 3 PMID:25153532;PMID:25495127;PMID:33807844 -1.11.1.19 reactive blue 19 basidiomycota sp. 22.0 22.0 1 PMID:33369202 -1.11.1.19 reactive blue 19 bjerkandera adusta 980.0 980.0 1 PMID:25655348 -1.11.1.19 reactive blue 19 cellulomonas bogoriensis 0.22 0.22 1 PMID:30934796 -1.11.1.19 reactive blue 19 irpex lacteus 187.9 79.9 4 PMID:23666335;PMID:33922393;PMID:34059116 -1.11.1.19 reactive blue 19 thermobifida fusca yx 10.0 10.0 1 PMID:19967355 -1.11.1.19 reactive blue 19 thermomonospora curvata 41.0 21.15 2 PMID:26205819;PMID:33807844 -1.11.1.19 reactive blue 19 vibrio cholerae 2.3 1.3 3 PMID:26431465;PMID:33756393 -1.11.1.19 reactive blue 4 dictyostelium discoideum 5.2 5.2 1 PMID:34200865 -1.11.1.19 reactive blue 4 thermomonospora curvata 110.0 110.0 1 PMID:26205819 -1.11.1.19 reactive blue 5 anabaena sp. 384.0 384.0 1 PMID:19801472 -1.11.1.19 reactive blue 5 auricularia auricula-judae 256.0 114.0 3 PMID:19756587;PMID:25495127 -1.11.1.19 reactive blue 5 geotrichum candidum 260.0 260.0 1 PMID:10049859 -1.11.1.19 reactive blue 5 pleurotus sapidus 18.0 18.0 1 PMID:28831735 -1.11.1.19 reactive blue 5 pseudomonas aeruginosa 0.0235 0.0235 1 PMID:22161141 -1.11.1.19 reactive blue 5 shewanella oneidensis mr-1 5.9 5.9 1 PMID:17654547 -1.11.1.19 reactive blue 5 thermomonospora curvata 29.0 29.0 1 PMID:26205819 -1.11.1.19 reactive blue 5 xylaria grammica 20.0 20.0 1 PMID:34572604 -1.11.1.19 reactive red 2 basidiomycota sp. 0.19 0.19 1 PMID:33369202 -1.11.1.19 veratryl alcohol auricularia auricula-judae 0.86 0.74 2 PMID:19756587 -1.11.1.19 veratryl alcohol bacillus subtilis 0.065 0.065 1 PMID:34687768 -1.11.1.19 veratryl alcohol dictyostelium discoideum 0.000338 0.000338 1 PMID:34200865 -1.11.1.19 veratryl alcohol irpex lacteus 3.9 2.7 3 PMID:23666335;PMID:33922393 -1.11.1.19 veratrylglycerol-beta-guaiacyl ether auricularia auricula-judae 0.3 0.3 1 PMID:33807844 -1.11.1.20 (5z)-n-(2-hydroxyethyl)-7-[(1r,4s,5r,6r)-6-[(1e,3s)-3-hydroxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl]hept-5-enamide mus musculus 0.09 0.09 1 PMID:18006499 -1.11.1.20 (5z,9alpha,11alpha,13e,15s)-9,11-epidioxy-15-hydroxy-prosta-5,13-dienoate mus musculus 0.25 0.25 1 PMID:18006499 -1.11.1.20 cumene hydroperoxide mus musculus 0.1 0.1 2 PMID:18006499 -1.11.1.20 h2o2 mus musculus 0.1 0.1 2 PMID:18006499 -1.11.1.20 prostaglandin h2 mus musculus 0.25 0.25 1 PMID:18006499 -1.11.1.20 prostamide h2 mus musculus 0.09 0.09 1 PMID:18006499 -1.11.1.20 t-butyl hydroperoxide mus musculus 0.09 0.09 1 PMID:18006499 -1.11.1.20 tert-butyl hydroperoxide mus musculus 0.09 0.09 1 PMID:18006499 -1.11.1.20 thioredoxin mus musculus 0.001 0.001 1 PMID:18006499 -1.11.1.21 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) archaeoglobus fulgidus 17.0 17.0 1 PMID:18178143 -1.11.1.21 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) burkholderia pseudomallei 7.9 7.9 1 PMID:18178143 -1.11.1.21 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) escherichia coli 17000.0 55.2 11 PMID:10801338;PMID:14678798;PMID:15147967;PMID:18178143;PMID:18413236;PMID:18635265;PMID:23018273 -1.11.1.21 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) geobacillus stearothermophilus 11.0 11.0 1 PMID:18178143 -1.11.1.21 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) mycobacterium tuberculosis 11500.0 55.0 7 PMID:16315359;PMID:18178143;PMID:22705398;PMID:23084782;PMID:25674665;PMID:9395452 -1.11.1.21 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) rhodobacter capsulatus 7.7 7.7 1 PMID:18178143 -1.11.1.21 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) synechocystis sp. 13.0 13.0 1 PMID:18178143 -1.11.1.21 2-dianisidine mycobacterium tuberculosis 3.48 3.48 1 PMID:12543676 -1.11.1.21 3,3',5,5'-tetramethylbenzidine mycobacterium tuberculosis 5220.0 5220.0 1 PMID:22705398 -1.11.1.21 ascorbate mycobacterium tuberculosis 520.0 520.0 1 PMID:22705398 -1.11.1.21 chlorpromazine mycobacterium tuberculosis 7940.0 7940.0 1 PMID:22705398 -1.11.1.21 h2o2 archaeoglobus fulgidus 15680.0 11725.0 2 PMID:18178143 -1.11.1.21 h2o2 bacillus pumilus 322000.0 322000.0 1 PMID:27016935 -1.11.1.21 h2o2 burkholderia pseudomallei 15900.0 5680.0 4 PMID:17063492;PMID:18178143 -1.11.1.21 h2o2 escherichia coli 18000.0 5300.0 9 PMID:10801338;PMID:14678798;PMID:15147967;PMID:18178143;PMID:18635265;PMID:23018273 -1.11.1.21 h2o2 geobacillus stearothermophilus 7600.0 5950.0 2 PMID:18178143 -1.11.1.21 h2o2 mycobacterium tuberculosis 10200.0 4350.0 11 PMID:12543676;PMID:16315359;PMID:17217949;PMID:18178143;PMID:22705398;PMID:25674665;PMID:9006925;PMID:9291321;PMID:9395452 -1.11.1.21 h2o2 neurospora crassa 551.0 324.5 2 PMID:29305053 -1.11.1.21 h2o2 pyricularia grisea 7010.0 6730.0 4 PMID:19000033;PMID:22822072;PMID:27293030 -1.11.1.21 h2o2 rhodobacter capsulatus 14100.0 10370.0 2 PMID:18178143 -1.11.1.21 h2o2 synechococcus elongatus pcc 7942 = fachb-805 7200.0 7200.0 1 PMID:9207193 -1.11.1.21 h2o2 synechocystis sp. 8000.0 3500.0 7 PMID:10543446;PMID:12603334;PMID:12731870;PMID:15134453;PMID:17217949;PMID:18178143;PMID:20026288 -1.11.1.21 h2o2 synechocystis sp. pcc 6803 3500.0 3500.0 1 PMID:12731870;PMID:15134453 -1.11.1.21 isoniazid mycobacterium tuberculosis 0.057 0.057 1 PMID:9291321 -1.11.1.21 n,n,n',n'-tetramethyl-p-phenylenediamine mycobacterium tuberculosis 7012.0 7012.0 1 PMID:22705398 -1.11.1.21 o-dianisidine escherichia coli 71.0 58.0 5 PMID:18413236 -1.11.1.21 o-dianisidine mycobacterium tuberculosis 5600.0 49.0 3 PMID:22705398;PMID:9291321 -1.11.1.21 o-dianisidine neurospora crassa 44.0 44.0 1 PMID:29305053 -1.11.1.21 peroxyacetic acid bacillus pumilus 19.42 19.42 1 PMID:27016935 -1.11.1.21 pyrogallol escherichia coli 69.0 56.0 5 PMID:18413236 -1.11.1.21 pyrogallol mycobacterium tuberculosis 630.0 630.0 1 PMID:22705398 -1.11.1.23 (s)-2-hydroxypropylphosphonic acid pseudomonas syringae 0.0028 0.0028 1 PMID:18656958 -1.11.1.24 cumene hydroperoxide cereibacter sphaeroides 0.281 0.2775 2 PMID:17644813 -1.11.1.24 cumene hydroperoxide fasciola hepatica 6.3 6.3 1 PMID:16938293 -1.11.1.24 cumene hydroperoxide salmonella enterica subsp. enterica serovar typhimurium 52.0 52.0 1 PMID:18165315 -1.11.1.24 cumene hydroperoxide seriola lalandi 15.2 11.25 2 PMID:20381631 -1.11.1.24 cumene hydroperoxide treponema pallidum 9.8 9.8 1 PMID:20304799 -1.11.1.24 cumene hydroperoxide xylella fastidiosa 0.41 0.41 1 PMID:20335172 -1.11.1.24 ethyl hydroperoxide salmonella enterica subsp. enterica serovar typhimurium 52.7 52.7 1 PMID:18165315 -1.11.1.24 h2o2 cereibacter sphaeroides 0.285 0.285 2 PMID:17644813 -1.11.1.24 h2o2 fasciola hepatica 15.8 15.8 1 PMID:16938293 -1.11.1.24 h2o2 lathyrus oleraceus 10.6 5.645 2 PMID:15333640;PMID:17881238 -1.11.1.24 h2o2 mycobacterium tuberculosis variant bovis 0.021 0.021 1 PMID:32557576 -1.11.1.24 h2o2 plasmodium falciparum 1.67 1.67 1 PMID:12946843 -1.11.1.24 h2o2 salmonella enterica subsp. enterica serovar typhimurium 52.4 52.4 1 PMID:18165315 -1.11.1.24 h2o2 seriola lalandi 24.6 23.450000000000003 2 PMID:20381631 -1.11.1.24 h2o2 toxoplasma gondii 0.83 0.83 1 PMID:15507457 -1.11.1.24 h2o2 treponema pallidum 17.0 17.0 1 PMID:20304799 -1.11.1.24 h2o2 trichoderma reesei 19.0 19.0 2 PMID:33259843 -1.11.1.24 h2o2 xylella fastidiosa 1.1 1.1 1 PMID:20335172 -1.11.1.24 reduced thioredoxin a vibrio vulnificus 2.9 1.4989999999999999 2 PMID:23095744 -1.11.1.24 t-butyl hydroperoxide seriola lalandi 10.4 6.800000000000001 2 PMID:20381631 -1.11.1.24 t-butyl hydroperoxide treponema pallidum 20.9 20.9 1 PMID:20304799 -1.11.1.24 t-butyl hydroperoxide xylella fastidiosa 2.0 2.0 1 PMID:20335172 -1.11.1.24 tert-butyl hydroperoxide fasciola hepatica 7.6 7.6 1 PMID:16938293 -1.11.1.24 tert-butyl hydroperoxide salmonella enterica subsp. enterica serovar typhimurium 54.7 54.7 1 PMID:18165315 -1.11.1.24 tert-butyl hydroperoxide toxoplasma gondii 2.79 2.79 1 PMID:15507457 -1.11.1.24 thioredoxin plasmodium falciparum 9.65 9.65 1 PMID:12946843 -1.11.1.24 thioredoxin treponema pallidum 20.9 17.0 3 PMID:20304799 -1.11.1.24 thioredoxin a synechocystis sp. pcc 6803 0.099 0.092 5 PMID:19820102 -1.11.1.24 thioredoxin b synechocystis sp. pcc 6803 0.212 0.072 5 PMID:19820102 -1.11.1.24 thioredoxin q synechocystis sp. pcc 6803 0.079 0.07100000000000001 4 PMID:19820102 -1.11.1.24 tryparedoxin 2 leishmania infantum 37.0 37.0 1 PMID:12446214 -1.11.1.25 benzoquinone thermotoga maritima 52.8 52.8 1 PMID:22866991 -1.11.1.25 cumene hydroperoxide populus x canadensis 0.9 0.9 1 PMID:15032877 -1.11.1.25 h2o2 populus x canadensis 2.6 2.6 1 PMID:15032877 -1.11.1.25 h2o2 thermotoga maritima 0.27 0.195 2 PMID:22866991 -1.11.1.25 phosphatidylcholine hydroperoxide populus x canadensis 2.1 2.1 1 PMID:15032877 -1.11.1.25 tert-butyl hydroperoxide populus x canadensis 1.5 1.5 1 PMID:15032877 -1.11.1.26 cumene hydroperoxide burkholderia thailandensis 29.7 20.65 2 PMID:31338075 -1.11.1.26 h2o2 burkholderia thailandensis 7.1 5.35 2 PMID:31338075 -1.11.1.26 h2o2 salmonella enterica subsp. enterica serovar typhimurium 40.0 40.0 2 PMID:28375740 -1.11.1.26 tert-butyl hydroperoxide burkholderia thailandensis 26.1 17.8 2 PMID:31338075 -1.11.1.28 7alpha-hydroperoxy-3beta-hydroxycholest-6-ene mycobacterium tuberculosis 0.178 0.16249999999999998 2 PMID:10766746 -1.11.1.28 [dihydrolipoamide acyltransferase, subunit e2 from alpha-ketoglutarate dehydrogenase complex]-n6-[(r)-dihydrolipoyl]-l-lysine xylella fastidiosa 17.95 17.95 1 PMID:20463026 -1.11.1.28 [dihydrolipoamide acyltransferase, subunit e2 from pyruvate dehydrogenase complexlipoyl-carrier protein]-n6-[(r)-dihydrolipoyl]-l-lysine xylella fastidiosa 9.5 9.5 1 PMID:20463026 -1.11.1.28 cumene hydroperoxide mycobacterium tuberculosis 0.067 0.05 2 PMID:10766746 -1.11.1.28 h2o2 mycobacterium tuberculosis 0.088 0.0865 2 PMID:10766746 -1.11.1.28 h2o2 xylella fastidiosa 9.53 9.53 1 PMID:20463026 -1.11.1.28 lipoamide xylella fastidiosa 90.9 90.9 1 PMID:20463026 -1.11.1.28 tert-butyl hydroperoxide mycobacterium tuberculosis 0.06 0.0475 2 PMID:10766746 -1.11.1.28 tert-butyl hydroperoxide xylella fastidiosa 17.95 17.95 1 PMID:20463026 -1.11.1.28 trans-pinocarveylhydroperoxide mycobacterium tuberculosis 0.015 0.013999999999999999 2 PMID:10766746 -1.11.1.5 1-methoxynaphthalene saccharomyces cerevisiae 7e-05 7e-05 1 PMID:23895311 -1.11.1.5 2,2-azinobis(3-ethylbenzthiazolinesulfonic acid) shewanella oneidensis 23.1 23.1 1 PMID:21742904 -1.11.1.5 acrylonitrile saccharomyces cerevisiae 0.01 0.01 1 PMID:24291498 -1.11.1.5 ascorbate saccharomyces cerevisiae 3.0 1.915 2 PMID:19061385;PMID:5845850 -1.11.1.5 cytochrome c saccharomyces cerevisiae 1510.0 1510.0 1 PMID:19061385 -1.11.1.5 ferrocytochrome c paracoccus denitrificans 17.2 17.2 1 * -1.11.1.5 ferrocytochrome c rhodobacter capsulatus 23.6 23.6 1 PMID:11737210 -1.11.1.5 ferrocytochrome c saccharomyces cerevisiae 2000.0 1750.0 2 PMID:5845850 -1.11.1.5 ferrocytochrome c2 rhodobacter capsulatus 17.7 17.7 1 PMID:11737210 -1.11.1.5 ferrocytochrome c555 methylococcus capsulatus 3.05 3.05 1 PMID:9325424 -1.11.1.5 guaiacol saccharomyces cerevisiae 4.4 4.25 2 PMID:19061385;PMID:5845850 -1.11.1.5 h2o2 geobacter sulfurreducens 15.5 15.5 1 PMID:19735665 -1.11.1.5 h2o2 nitrosomonas europaea 4.3 4.3 1 PMID:26575087 -1.11.1.5 horse ferrocytochrome c rhodobacter capsulatus 40.0 40.0 1 PMID:9851688 -1.11.1.5 horse heart ferrocytochrome c saccharomyces cerevisiae 850.3 97.89999999999999 4 PMID:15071191 -1.11.1.5 pyrogallol saccharomyces cerevisiae 8.0 8.0 1 PMID:5845850 -1.11.1.5 rhodobacter capsulatus ferrocyctochrome c2 rhodobacter capsulatus 40.0 40.0 1 PMID:9851688 -1.11.1.5 yeast ferrocytochrome c saccharomyces cerevisiae 1362.0 147.65 4 PMID:15071191 -1.11.1.6 h2o2 bacillus pumilus 339000.0 339000.0 1 PMID:25663126 -1.11.1.6 h2o2 bacillus sp. (in: firmicutes) 175000.0 162000.0 2 PMID:18923550 -1.11.1.6 h2o2 capra capra 217000.0 217000.0 1 PMID:8302290 -1.11.1.6 h2o2 escherichia coli 26000.0 66.5 20 PMID:14678798;PMID:18413236;PMID:18635265;PMID:21998098;PMID:374409 -1.11.1.6 h2o2 gluconobacter oxydans 62800.0 62800.0 1 PMID:21317031 -1.11.1.6 h2o2 haloarcula marismortui 3000.0 3000.0 1 PMID:18007045 -1.11.1.6 h2o2 komagataella pastoris 850000.0 850000.0 1 PMID:11421814 -1.11.1.6 h2o2 mycothermus thermophilus 203410.0 203410.0 1 PMID:30289408 -1.11.1.6 h2o2 neurospora crassa 125000.0 125000.0 1 PMID:12033445 -1.11.1.6 h2o2 oryza sativa 80000.0 80000.0 1 PMID:21978604 -1.11.1.6 h2o2 pyrobaculum calidifontis 29000.0 29000.0 1 PMID:12029047 -1.11.1.6 h2o2 talaromyces piceae 2830000.0 2830000.0 1 * -1.11.1.6 h2o2 thermoascus aurantiacus 107000.0 107000.0 1 * -1.11.1.6 h2o2 thermus brockianus 360000.0 360000.0 1 PMID:12892493 -1.11.1.6 h2o2 xanthomonas campestris 255000.0 255000.0 1 PMID:12520360 -1.11.1.6 h2o2 zavarzinia compransoris 23300.0 23300.0 1 * -1.11.1.7 2,2'-azino-bis(3-ethylbenzthiazole-6-sulfonic acid) streptomyces lividans 1.12 0.81 2 PMID:28695933 -1.11.1.7 2,2'-azino-bis-(3-ethylbenzthiazole-6-sulfonic acid) armoracia rusticana 810.0 773.0 2 PMID:12628703 -1.11.1.7 2,2'-azino-bis-(3-ethylbenzthiazole-6-sulfonic acid) glycine max 2663.0 1946.5 2 PMID:12628703 -1.11.1.7 2,2'-azino-bis-(3-ethylbenzthiazole-6-sulfonic acid) neurospora crassa 0.3 0.3 1 * -1.11.1.7 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) amphitrite ornata 25.72 19.695 2 PMID:26375307 -1.11.1.7 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) armoracia rusticana 571.0 571.0 1 PMID:26375307 -1.11.1.7 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) persea americana 789.0 789.0 1 * -1.11.1.7 2,3-dimethoxyphenol armoracia rusticana 100.0 100.0 1 PMID:15493874 -1.11.1.7 2,4,6-tribromophenol amphitrite ornata 1.87 1.85 2 PMID:26375307 -1.11.1.7 2,4,6-tribromophenol armoracia rusticana 223.0 223.0 1 PMID:26375307 -1.11.1.7 2,4,6-trichlorophenol amphitrite ornata 1.05 0.875 2 PMID:26375307 -1.11.1.7 2,4,6-trichlorophenol armoracia rusticana 52.5 52.5 1 PMID:26375307 -1.11.1.7 2,6-dimethyloxyphenol streptomyces lividans 0.32 0.21000000000000002 2 PMID:28695933 -1.11.1.7 2-chloro-4-methoxyphenol armoracia rusticana 1900.0 1900.0 1 PMID:15493874 -1.11.1.7 3,3',5,5'-tetramethylbenzidine armoracia rusticana 790.0 435.0 3 PMID:12693977 -1.11.1.7 3,3',5,5'-tetramethylbenzidine homo sapiens 1.5 1.5 1 PMID:18929642 -1.11.1.7 3,4-dimethoxyphenol armoracia rusticana 1800.0 1800.0 1 PMID:15493874 -1.11.1.7 3,5-dibromo-4-hydroxybenzonitrile bjerkandera adusta 6.8 6.8 1 * -1.11.1.7 3,5-dimethoxyphenol armoracia rusticana 90.0 90.0 1 PMID:15493874 -1.11.1.7 3-(4-hydroxyphenyl)propanoic acid armoracia rusticana 300.0 300.0 1 PMID:15493874 -1.11.1.7 3-methyltyrosine escherichia coli 17.8 17.8 1 PMID:22187429 -1.11.1.7 4-aminophenol armoracia rusticana 1272.0 1272.0 1 PMID:18439429 -1.11.1.7 amplex red armoracia rusticana 240.0 240.0 1 PMID:19334781 -1.11.1.7 br- homo sapiens 0.46 0.46 1 PMID:16396635 -1.11.1.7 caffeic acid persea americana 189.0 189.0 1 * -1.11.1.7 cumene hydroperoxide escherichia coli 70.1 70.1 1 PMID:12514184 -1.11.1.7 cumene hydroperoxide mycobacterium avium 330.0 330.0 1 PMID:19827095 -1.11.1.7 esculetin armoracia rusticana 890.0 880.5 4 PMID:17284853 -1.11.1.7 eugenol persea americana 344.0 344.0 1 * -1.11.1.7 guaiacol armoracia rusticana 990.0 10.75 8 PMID:15493874;PMID:17973090;PMID:25335829 -1.11.1.7 guaiacol persea americana 49.0 49.0 1 * -1.11.1.7 guaiacol plasmodium falciparum 1.3 1.3 1 PMID:15802233 -1.11.1.7 guaiacol streptomyces lividans 0.4 0.227 2 PMID:28695933 -1.11.1.7 h2o2 armoracia rusticana 201.8 201.8 1 PMID:19833360 -1.11.1.7 h2o2 escherichia coli 76.0 76.0 1 PMID:12514184 -1.11.1.7 h2o2 mycobacterium avium 13.0 13.0 1 PMID:19827095 -1.11.1.7 h2o2 neurospora crassa 0.3 0.3 1 * -1.11.1.7 h2o2 oryza sativa 6.13 6.13 1 PMID:19833360 -1.11.1.7 h2o2 sorghum bicolor 87.0 48.45 2 PMID:26666777 -1.11.1.7 k4[fe(cn)6] streptomyces lividans 295.0 202.0 2 PMID:28695933 -1.11.1.7 l-tyrosine escherichia coli 12.3 12.3 1 PMID:22187429 -1.11.1.7 m-hydroxyanisol armoracia rusticana 430.0 430.0 1 PMID:15493874 -1.11.1.7 mn2+ pleurotus eryngii 298.0 298.0 1 PMID:16246366 -1.11.1.7 n,n,n',n'-tetramethyl-p-phenylenediamine armoracia rusticana 650.0 650.0 1 PMID:15493874 -1.11.1.7 o-dianisidine persea americana 398.0 398.0 1 * -1.11.1.7 o-phenylenediamine armoracia rusticana 528.0 528.0 1 PMID:12693977 -1.11.1.7 o-phenylenediamine chromolaena odorata 744.6 744.6 1 PMID:16632882 -1.11.1.7 o-toluidine armoracia rusticana 270.0 270.0 1 PMID:15493874 -1.11.1.7 p-hydroxybenzoic acid armoracia rusticana 311.7 311.7 1 PMID:18439429 -1.11.1.7 pentachlorophenol bjerkandera adusta 3.2 3.2 1 * -1.11.1.7 phenol armoracia rusticana 691.7 691.7 1 PMID:18439429 -1.11.1.7 pyrogallol chromolaena odorata 102.5 102.5 1 PMID:16632882 -1.11.1.7 pyrogallol persea americana 230.0 230.0 1 * -1.11.1.7 reactive black 5 pleurotus eryngii 5.0 5.0 1 PMID:16246366 -1.11.1.7 reduced 2,2'-azino-bis-(3-ethylbenzthiazole-6-sulfonic acid) chromolaena odorata 2383.0 2383.0 1 PMID:16632882 -1.11.1.7 scn- homo sapiens 13.6 13.6 1 PMID:16396635 -1.11.1.7 tert-butyl hydroperoxide mycobacterium avium 320.0 320.0 1 PMID:19827095 -1.11.1.7 veratryl alcohol pleurotus eryngii 8.0 8.0 1 PMID:16246366 -1.11.1.7 veratryl alcohol streptomyces lividans 0.82 0.82 1 PMID:28695933 -1.11.1.8 3,3',5,5'-tetramethylbenzidine homo sapiens 34.6 34.6 1 PMID:15000688 -1.11.1.8 3,3'-dimethoxybenzidine homo sapiens 11.9 11.9 1 PMID:15000688 -1.11.1.8 3,3'-dimethylbenzidine homo sapiens 27.5 27.5 1 PMID:15000688 -1.11.1.8 benzidine homo sapiens 6.0 6.0 1 PMID:15000688 -1.11.1.8 br- ascophyllum nodosum 71.0 71.0 1 PMID:18492479 -1.11.1.8 i- ascophyllum nodosum 75.0 75.0 1 PMID:18492479 -1.11.1.9 cumene peroxide lucilia cuprina 35.78 18.29 2 * -1.11.1.9 gsh homo sapiens 408.3 221.7 7 PMID:18163571;PMID:18373941 -1.11.1.9 h2o2 homo sapiens 670.0 316.7 7 PMID:18163571;PMID:18373941 -1.11.1.9 h2o2 lucilia cuprina 44.03 24.865000000000002 2 * -1.11.1.9 tert-butyl hydroperoxide lucilia cuprina 25.3 25.3 1 * -1.11.2.1 1,2-dimethoxy-4-(methoxymethyl)benzene cyclocybe aegerita 720.0 720.0 1 PMID:23608506 -1.11.2.1 1,4-dimethoxybenzene cyclocybe aegerita 593.0 525.0 2 * -1.11.2.1 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) candolleomyces aberdarensis 97.0 97.0 1 PMID:34288703 -1.11.2.1 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) cyclocybe aegerita 546.0 339.0 4 PMID:17410351;PMID:24682297;PMID:26002501 -1.11.2.1 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) hypoxylon sp. ec38 17.29 17.29 1 PMID:34540338 -1.11.2.1 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) marasmius rotula 25.0 25.0 1 PMID:21988939 -1.11.2.1 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonate) achaetomiella virescens 157.2 157.2 1 PMID:31980430 -1.11.2.1 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonate) coprinellus radians 123.0 123.0 1 PMID:17601809 -1.11.2.1 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonate) cyclocybe aegerita 283.0 283.0 1 PMID:15294788 -1.11.2.1 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonate) daldinia caldariorum 6.73 6.73 1 PMID:31980430 -1.11.2.1 2,6-dimethoxyphenol candolleomyces aberdarensis 87.0 87.0 1 PMID:34288703 -1.11.2.1 2,6-dimethoxyphenol coprinellus radians 2.0 2.0 1 PMID:17601809 -1.11.2.1 2,6-dimethoxyphenol cyclocybe aegerita 108.0 108.0 2 PMID:15294788;PMID:17410351 -1.11.2.1 2,6-dimethoxyphenol hypoxylon sp. ec38 11.0 11.0 1 PMID:34540338 -1.11.2.1 2,6-dimethoxyphenol marasmius rotula 70.0 70.0 1 PMID:21988939 -1.11.2.1 2-methyl-2-butene cyclocybe aegerita 1257.0 1257.0 1 PMID:23608506 -1.11.2.1 3,4-dimethoxybenzyl alcohol hypoxylon sp. ec38 7.15 7.15 1 PMID:34540338 -1.11.2.1 4-hydroxy-trans-stilbene coprinopsis cinerea 6.6 6.6 1 * -1.11.2.1 4-hydroxy-trans-stilbene cyclocybe aegerita 225.0 225.0 1 * -1.11.2.1 4-hydroxy-trans-stilbene marasmius rotula 11.7 11.7 1 * -1.11.2.1 5-nitro-1,3-benzodioxole candolleomyces aberdarensis 22.0 22.0 1 PMID:34288703 -1.11.2.1 5-nitro-1,3-benzodioxole cyclocybe aegerita 498.0 338.0 3 PMID:24682297;PMID:26002501 -1.11.2.1 5-nitro-1,3-benzodioxole hypoxylon sp. ec38 10.4 10.4 1 PMID:34540338 -1.11.2.1 5-nitro-1,3-benzodioxole thermothelomyces thermophilus 7.1 7.1 1 PMID:34631225 -1.11.2.1 benzene cyclocybe aegerita 8.0 8.0 1 PMID:23327645 -1.11.2.1 benzyl alcohol achaetomiella virescens 62.9 62.9 1 PMID:31980430 -1.11.2.1 benzyl alcohol candolleomyces aberdarensis 214.0 214.0 1 PMID:34288703 -1.11.2.1 benzyl alcohol coprinellus radians 176.0 176.0 1 PMID:17601809 -1.11.2.1 benzyl alcohol cyclocybe aegerita 524.0 307.0 5 PMID:15294788;PMID:17410351;PMID:24682297;PMID:26002501 -1.11.2.1 benzyl alcohol daldinia caldariorum 16.09 16.09 1 PMID:31980430 -1.11.2.1 benzyl alcohol hypoxylon sp. ec38 4.56 4.56 1 PMID:34540338 -1.11.2.1 benzyl alcohol marasmius rotula 62.0 62.0 1 PMID:21988939 -1.11.2.1 cortisone marasmius rotula 0.107 0.107 1 PMID:29604496 -1.11.2.1 cortisone marasmius wettsteinii 0.102 0.102 1 PMID:29604496 -1.11.2.1 cyclohexane coprinopsis cinerea 13.0 13.0 1 * -1.11.2.1 cyclohexane cyclocybe aegerita 72.0 54.5 2 PMID:23608506 -1.11.2.1 cyclohexane marasmius rotula 43.0 43.0 1 * -1.11.2.1 cyclohexanol coprinopsis cinerea 3.0 3.0 1 * -1.11.2.1 cyclohexanol cyclocybe aegerita 5.0 5.0 1 * -1.11.2.1 cyclohexanol marasmius rotula 31.0 31.0 1 * -1.11.2.1 diclofenac cyclocybe aegerita 582.0 476.5 2 * -1.11.2.1 dimethylene-5-nitrobenzene cyclocybe aegerita 322.0 296.5 2 * -1.11.2.1 ethylbenzene cyclocybe aegerita 410.0 410.0 1 * -1.11.2.1 h2o2 candolleomyces aberdarensis 114.0 114.0 1 PMID:34288703 -1.11.2.1 h2o2 coprinellus radians 471.0 471.0 1 PMID:17601809 -1.11.2.1 h2o2 coprinopsis cinerea 1910.0 1910.0 1 * -1.11.2.1 h2o2 cyclocybe aegerita 676.0 328.5 6 PMID:15294788;PMID:17410351;PMID:24682297;PMID:26002501 -1.11.2.1 h2o2 hypoxylon sp. ec38 8.0 8.0 1 PMID:34540338 -1.11.2.1 h2o2 marasmius rotula 1665.0 870.5 2 PMID:21988939 -1.11.2.1 h2o2 sulfurisphaera tokodaii 0.16 0.13 3 PMID:24410761 -1.11.2.1 indole hypoxylon sp. ec38 0.89 0.89 1 PMID:34540338 -1.11.2.1 isophorone chaetomium globosum 4.4 4.4 1 * -1.11.2.1 isophorone cyclocybe aegerita 20.1 20.1 1 * -1.11.2.1 isophorone mycothermus thermophilus 42.0 42.0 1 * -1.11.2.1 methyl 3,4-dimethoxybenzyl ether cyclocybe aegerita 720.0 720.0 1 PMID:19713216 -1.11.2.1 naphthalene achaetomiella virescens 1.08 1.08 1 PMID:31980430 -1.11.2.1 naphthalene coprinellus radians 15.0 15.0 1 PMID:17601809 -1.11.2.1 naphthalene cyclocybe aegerita 166.0 166.0 2 PMID:17410351;PMID:23608506 -1.11.2.1 naphthalene daldinia caldariorum 22.1 22.1 1 PMID:31980430 -1.11.2.1 naphthalene marasmius rotula 33.0 33.0 1 PMID:21988939 -1.11.2.1 oleic acid chaetomium globosum 8.1 8.1 1 * -1.11.2.1 oleic acid marasmius rotula 2.6 2.6 1 * -1.11.2.1 propylbenzene cyclocybe aegerita 194.0 194.0 1 * -1.11.2.1 pyridine cyclocybe aegerita 0.21 0.21 2 PMID:19022254;PMID:23608506 -1.11.2.1 testosterone chaetomium globosum 0.26 0.26 1 PMID:28103392 -1.11.2.1 tetrahydrofuran cyclocybe aegerita 33.0 33.0 1 PMID:19713216 -1.11.2.1 trans-stilbene coprinopsis cinerea 9.1 9.1 1 * -1.11.2.1 trans-stilbene cyclocybe aegerita 85.7 85.7 1 * -1.11.2.1 trans-stilbene marasmius rotula 4.2 4.2 1 * -1.11.2.1 veratryl alcohol achaetomiella virescens 2.24 2.24 1 PMID:31980430 -1.11.2.1 veratryl alcohol candolleomyces aberdarensis 106.0 106.0 1 PMID:34288703 -1.11.2.1 veratryl alcohol coprinellus radians 34.0 34.0 1 PMID:17601809 -1.11.2.1 veratryl alcohol cyclocybe aegerita 203.0 86.5 6 PMID:15294788;PMID:17410351;PMID:24682297;PMID:26002501 -1.11.2.1 veratryl alcohol daldinia caldariorum 2.39 2.39 1 PMID:31980430 -1.11.2.1 veratryl alcohol marasmius rotula 49.0 49.0 1 PMID:21988939 -1.11.2.2 1-acetyl-4-(methylsulfanyl)benzene homo sapiens 56.0 30.1 2 PMID:9742209 -1.11.2.2 1-chloro-4-(methylsulfanyl)benzene homo sapiens 35.0 20.0 2 PMID:9742209 -1.11.2.2 1-methoxy-4-(methylsulfanyl)benzene homo sapiens 6.0 3.215 2 PMID:9742209 -1.11.2.2 1-methyl-4-(methylsulfanyl)benzene homo sapiens 20.0 11.5 2 PMID:9742209 -1.11.2.2 1-nitro-4-(methylsulfanyl)benzene homo sapiens 5.5 3.65 2 PMID:9742209 -1.11.2.2 10-acetyl-3,7-dihydroxyphenoxazine homo sapiens 186.0 186.0 1 PMID:24632143 -1.11.2.2 4-(methylsulfanyl)aniline homo sapiens 40.0 25.0 2 PMID:9742209 -1.11.2.2 benzothiophene homo sapiens 1.6 1.3 2 PMID:9742209 -1.11.2.2 benzyl methyl sulfide homo sapiens 8.0 4.5 2 PMID:9742209 -1.11.2.2 catechol bos taurus 2.2e-05 2.2e-05 1 PMID:12620685 -1.11.2.2 catechol homo sapiens 1.2e-05 1.2e-05 1 PMID:12620685 -1.11.2.2 cl- homo sapiens 28.5 28.5 1 PMID:10766781 -1.11.2.2 dopamine bos taurus 1.6e-06 1.6e-06 1 PMID:12620685 -1.11.2.2 dopamine homo sapiens 1e-07 1e-07 1 PMID:12620685 -1.11.2.2 h2o2 homo sapiens 320.0 25.0 3 PMID:2155024 -1.11.2.2 nitrite homo sapiens 0.7 0.7 1 PMID:10766781 -1.11.2.2 phenyl propan-2-yl sulfide homo sapiens 14.0 10.65 2 PMID:9742209 -1.11.2.2 scn- bos taurus 3.3e-06 3.3e-06 1 PMID:12620685 -1.11.2.2 scn- homo sapiens 1.6e-07 1.6e-07 1 PMID:12620685 -1.11.2.2 thioanisole homo sapiens 12.0 8.0 2 PMID:9742209 -1.11.2.2 thiocyanate homo sapiens 30.5 30.5 1 PMID:10766781 -1.11.2.5 3-methyl-l-tyrosine streptomyces lavendulae 0.476 0.476 1 PMID:22187429 -1.11.2.5 l-tyrosine streptomyces lavendulae 0.205 0.205 1 PMID:22187429 -1.11.2.6 h2o2 streptomyces refuineus 1.5 1.5 1 PMID:21919439 -1.11.2.6 l-tyrosine streptomyces refuineus 0.576 0.576 1 PMID:21919439 -1.12.1.2 ferrocyanide cupriavidus necator 372.0 222.0 3 PMID:15838039 -1.12.1.2 h2 cupriavidus necator 372.0 177.5 4 PMID:15838039 -1.12.1.2 nad+ cupriavidus necator 143.0 143.0 1 PMID:15838039 -1.12.1.2 nadh cupriavidus necator 222.0 222.0 3 PMID:15838039 -1.12.1.2 nadph cupriavidus necator 2.0 2.0 1 PMID:15838039 -1.12.1.2 oxidized benzyl viologen cupriavidus necator 120.0 120.0 1 PMID:15838039 -1.12.2.1 [fe] hydrogenase-cytochrome c3 complex nitratidesulfovibrio vulgaris 462.0 462.0 1 PMID:15780995 -1.12.2.1 [fe] hydrogenase-cytochrome c3-cytochrome hmc complex nitratidesulfovibrio vulgaris 2.3 2.3 1 PMID:15780995 -1.12.2.1 [fe] hydrogenase-cytochrome hmc complex nitratidesulfovibrio vulgaris 0.15 0.15 1 PMID:15780995 -1.12.2.1 ferricytochrome c nitratidesulfovibrio vulgaris 49.0 49.0 1 PMID:16460012 -1.12.2.1 ferricytochrome c3 desulfomicrobium norvegicum 38.0 38.0 1 PMID:10606770 -1.12.2.1 ferricytochrome c3 nitratidesulfovibrio vulgaris 490.0 490.0 1 PMID:10606770 -1.12.2.1 methyl viologen bacteria 3.6 3.6 1 * -1.12.2.1 mutant cytochrome c k101m nitratidesulfovibrio vulgaris 51.0 51.0 1 PMID:16460012 -1.12.2.1 mutant cytochrome c k15m nitratidesulfovibrio vulgaris 45.0 45.0 1 PMID:16460012 -1.12.2.1 mutant cytochrome c k26m nitratidesulfovibrio vulgaris 44.0 44.0 1 PMID:16460012 -1.12.2.1 mutant cytochrome c k57m nitratidesulfovibrio vulgaris 48.0 48.0 1 PMID:16460012 -1.12.2.1 mutant cytochrome c k58m nitratidesulfovibrio vulgaris 45.0 45.0 1 PMID:16460012 -1.12.2.1 mutant cytochrome c k60m nitratidesulfovibrio vulgaris 46.0 46.0 1 PMID:16460012 -1.12.2.1 mutant cytochrome c k72m nitratidesulfovibrio vulgaris 42.0 42.0 1 PMID:16460012 -1.12.2.1 mutant cytochrome c k94m nitratidesulfovibrio vulgaris 45.0 45.0 1 PMID:16460012 -1.12.2.1 mutant cytochrome c k95m nitratidesulfovibrio vulgaris 45.0 45.0 1 PMID:16460012 -1.12.2.1 mutant cytochrome c y65a nitratidesulfovibrio vulgaris 49.0 49.0 1 PMID:16460012 -1.12.2.1 mutant cytochrome c y66l nitratidesulfovibrio vulgaris 47.0 47.0 1 PMID:16460012 -1.12.2.1 mutant cytochrome c3 k10m nitratidesulfovibrio vulgaris 48.0 48.0 1 PMID:16460012 -1.12.5.1 h2 mycolicibacterium smegmatis 7.05 7.05 1 * -1.12.7.2 h2 clostridium acetobutylicum 483.0 454.0 3 PMID:17681007 -1.12.7.2 h2 sporomusa sphaeroides 0.683 0.683 1 PMID:8593101 -1.12.98.1 coenzyme f0 methanothermobacter thermautotrophicus 2250.0 1487.5 2 PMID:3663586;PMID:7061485 -1.12.98.1 coenzyme f420 methanococcus voltae 17.5 17.5 1 PMID:3121317 -1.12.98.1 coenzyme f420 methanothermobacter thermautotrophicus 2050.0 1387.5 2 PMID:3663586;PMID:7061485 -1.12.98.1 methyl viologen methanothermobacter thermautotrophicus 4000.0 2250.0 3 PMID:3663586;PMID:7061485 -1.12.98.1 oxidized coenzyme f420 methanosarcina barkeri 353.0 353.0 1 PMID:2550229 -1.12.98.1 oxidized methyl viologen methanosarcina barkeri 9226.0 9226.0 1 PMID:2550229 -1.12.98.2 5,10-methenyltetrahydromethanopterin methanothermobacter marburgensis 975.0 975.0 1 PMID:1521540 -1.12.98.2 5,10-methylenetetrahydromethanopterin methanothermobacter marburgensis 1462.0 1462.0 1 PMID:1521540 -1.12.99.6 abz-vaa allochromatium vinosum 9000.0 9000.0 1 PMID:15157115 -1.12.99.6 benzyl viologen hydrogenophaga sp. 240.0 240.0 1 PMID:19025569 -1.12.99.6 cr6+ desulfomicrobium norvegicum 0.23 0.23 1 PMID:12861426 -1.12.99.6 cr6+ nitratidesulfovibrio vulgaris 1.3 1.3 1 PMID:12861426 -1.12.99.6 cr6+ solidesulfovibrio fructosivorans 0.09 0.09 1 PMID:12861426 -1.12.99.6 methionaquinone hydrogenobacter thermophilus 48.3 48.3 1 PMID:10803945 -1.12.99.6 methyl viologen hydrogenophaga sp. 20.0 20.0 1 PMID:19025569 -1.12.99.6 methylene blue hydrogenophaga sp. 560.0 560.0 1 PMID:19025569 -1.13.11.1 2,3-dihydroxybenzoic acid rhodococcus opacus 0.28 0.28 1 PMID:20040374 -1.13.11.1 3-chlorocatechol rhodococcus opacus 0.18 0.18 1 PMID:20040374 -1.13.11.1 3-methylcatechol acinetobacter radioresistens 1.59 1.59 1 PMID:20869471 -1.13.11.1 3-methylcatechol pseudomonas aeruginosa 1.1 1.1 1 * -1.13.11.1 3-methylcatechol pseudomonas reinekei 2.3 1.5499999999999998 2 PMID:17172348 -1.13.11.1 3-methylcatechol ralstonia sp. 0.4 0.4 1 PMID:11676005 -1.13.11.1 3-methylcatechol rhodococcus opacus 10.62 10.62 1 PMID:20040374 -1.13.11.1 3-methylcatechol rhodococcus rhodochrous 9.5 9.5 1 * -1.13.11.1 4,5-dichlorocatechol acinetobacter radioresistens 0.18 0.18 1 PMID:20869471 -1.13.11.1 4,5-difluorocatechol pseudomonas putida 0.4 0.4 1 PMID:9799107 -1.13.11.1 4-bromocatechol pseudomonas putida 0.63 0.63 1 PMID:9799107 -1.13.11.1 4-chloro-5-fluorocatechol pseudomonas putida 0.4 0.4 1 PMID:9799107 -1.13.11.1 4-chlorocatechol acinetobacter radioresistens 0.83 0.83 1 PMID:20869471 -1.13.11.1 4-chlorocatechol cupriavidus necator 1.0 1.0 1 PMID:8661943 -1.13.11.1 4-chlorocatechol pseudomonas putida 1.3 1.3 1 PMID:9799107 -1.13.11.1 4-chlorocatechol pseudomonas reinekei 1.7 1.2 2 PMID:17172348 -1.13.11.1 4-chlorocatechol rhodococcus opacus 0.27 0.27 1 PMID:20040374 -1.13.11.1 4-fluorocatechol cupriavidus necator 4.0 4.0 1 PMID:8661943 -1.13.11.1 4-fluorocatechol pseudomonas putida 3.4 3.4 1 PMID:9799107 -1.13.11.1 4-methylcatechol acinetobacter radioresistens 5.45 5.45 1 PMID:20869471 -1.13.11.1 4-methylcatechol candida albicans 5.6 5.6 1 PMID:17089147 -1.13.11.1 4-methylcatechol cupriavidus necator 4.0 4.0 1 PMID:8661943 -1.13.11.1 4-methylcatechol pseudomonas aeruginosa 5.6 5.6 1 * -1.13.11.1 4-methylcatechol pseudomonas putida 12.0 12.0 1 PMID:9799107 -1.13.11.1 4-methylcatechol pseudomonas reinekei 20.7 11.7 2 PMID:17172348 -1.13.11.1 4-methylcatechol ralstonia sp. 1.6 1.6 1 PMID:11676005 -1.13.11.1 4-methylcatechol rhodococcus opacus 7.32 7.32 1 PMID:20040374 -1.13.11.1 4-methylcatechol rhodococcus rhodochrous 6.3 6.3 1 * -1.13.11.1 catechol acinetobacter radioresistens 48.7 30.03 5 PMID:11307956;PMID:20869471;PMID:23224984;PMID:9369233 -1.13.11.1 catechol candida albicans 8.0 8.0 1 PMID:17089147 -1.13.11.1 catechol cupriavidus campinensis 3.65 3.65 1 PMID:31900038 -1.13.11.1 catechol cupriavidus necator 20.0 20.0 1 PMID:8661943 -1.13.11.1 catechol pseudomonas aeruginosa 7.2 7.2 1 * -1.13.11.1 catechol pseudomonas fluorescens 26.7 26.7 1 PMID:13502352 -1.13.11.1 catechol pseudomonas putida 54.0 47.0 4 PMID:2295613;PMID:9799107 -1.13.11.1 catechol pseudomonas reinekei 8.7 8.1 2 PMID:17172348 -1.13.11.1 catechol ralstonia sp. 9.6 9.6 1 PMID:11676005 -1.13.11.1 catechol rhodococcus opacus 10.23 10.23 1 PMID:20040374 -1.13.11.1 catechol rhodococcus rhodochrous 11.6 11.6 1 * -1.13.11.1 catechol stutzerimonas stutzeri 16.13 16.13 1 PMID:32582076 -1.13.11.1 hydroxyquinol rhodococcus opacus 0.28 0.28 1 PMID:20040374 -1.13.11.1 protocatechuate rhodococcus opacus 0.04 0.04 1 PMID:20040374 -1.13.11.1 pyrogallol rhodococcus opacus 2.41 2.41 1 PMID:20040374 -1.13.11.11 l-tryptophan homo sapiens 1071.0 536.805 2 PMID:25066423;PMID:33142415 -1.13.11.12 (5z,8z,11z,14z)-eicosatetra-5,8,11,14-enoic acid fusarium oxysporum 1.71 1.71 1 PMID:23741422 -1.13.11.12 (6z,9z,12z)-octadeca-6,9,12-trienoic acid fusarium oxysporum 18.58 18.58 1 PMID:23741422 -1.13.11.12 (9z,12z)-octadeca-9,12-dienoic acid fusarium oxysporum 2.611 2.611 1 PMID:23741422 -1.13.11.12 (9z,12z,15z)-9,12,15-octadecatrienoic acid fusarium oxysporum 1.566 1.566 1 PMID:23741422 -1.13.11.12 5s-hydroperoxy-6e,8z,10e,14z-eicosatetraenoic acid homo sapiens 1.8 1.8 1 PMID:33048542 -1.13.11.12 5s-hydroxy-6e,8z,10e,14z-eicosatetraenoic acid homo sapiens 1.1 1.1 1 PMID:33048542 -1.13.11.12 alpha-linolenate burkholderia thailandensis 42.0 42.0 1 PMID:25586578 -1.13.11.12 arachidonate burkholderia thailandensis 112.0 112.0 1 PMID:25586578 -1.13.11.12 arachidonate homo sapiens 10.0 10.0 1 PMID:33048542 -1.13.11.12 arachidonic acid myxococcus xanthus 66.0 66.0 1 PMID:28552618 -1.13.11.12 gamma-linolenate burkholderia thailandensis 13.6 13.6 1 PMID:25586578 -1.13.11.12 linoleate burkholderia thailandensis 93.7 93.7 1 PMID:25586578 -1.13.11.12 linoleic acid cucumis melo var. makuwa 5492.88 3965.74 2 PMID:27101009 -1.13.11.12 linoleic acid glycine max 64.0 38.14 2 PMID:18793849;PMID:32732043 -1.13.11.12 linoleic acid myxococcus xanthus 13.3 13.3 1 PMID:28552618 -1.13.11.12 linoleic acid olea europaea 48.16 48.16 1 PMID:19268561 -1.13.11.12 linoleic acid pseudomonas aeruginosa 162.4 162.4 1 PMID:26361973 -1.13.11.12 linolenic acid cucumis melo var. makuwa 2442.96 2142.33 2 PMID:27101009 -1.13.11.12 linolenic acid olea europaea 47.78 47.78 1 PMID:19268561 -1.13.11.15 2,3-dihydroxybenzoate brevibacterium fuscum 0.02 0.02 1 PMID:14505375 -1.13.11.15 3,4-dihydroxyphenylacetate arthrobacter globiformis 4.6 4.6 1 PMID:16217642 -1.13.11.15 3,4-dihydroxyphenylacetate brevibacterium fuscum 10.0 10.0 4 PMID:14505375;PMID:15568806;PMID:15882056 -1.13.11.15 3,4-dihydroxyphenylacetate pseudomonas aeruginosa 63.5 62.95 2 PMID:28158217 -1.13.11.15 4-nitrocatechol brevibacterium fuscum 0.4 0.225 2 PMID:15568806 -1.13.11.16 3-(2,3-dihydroxyphenyl)propionate escherichia coli 29.0 29.0 1 PMID:8399388 -1.13.11.16 3-methylcatechol escherichia coli 3.6 3.6 1 PMID:8399388 -1.13.11.16 catechol escherichia coli 2.0 2.0 1 PMID:8399388 -1.13.11.18 bacillithiol persulfide staphylococcus aureus 19.7 19.7 1 PMID:26177047 -1.13.11.18 coassh staphylococcus aureus 19.3 19.3 1 PMID:26177047 -1.13.11.18 glutathione acidithiobacillus caldus 181.0 181.0 1 PMID:30072973 -1.13.11.18 o2 paraburkholderia phytofirmans 143.0 143.0 1 PMID:28684420 -1.13.11.18 s-sulfanyl-l-cysteine staphylococcus aureus 8.0 8.0 1 PMID:26177047 -1.13.11.18 s-sulfanylglutathione acidithiobacillus caldus 198.0 198.0 1 PMID:30072973 -1.13.11.18 s-sulfanylglutathione homo sapiens 47.0 47.0 1 PMID:29980601 -1.13.11.18 s-sulfanylglutathione paraburkholderia phytofirmans 143.0 143.0 1 PMID:28684420 -1.13.11.18 s-sulfanylglutathione staphylococcus aureus 6.5 6.5 1 PMID:26177047 -1.13.11.2 2,2',3-trihydroxybiphenylether pseudomonas sp. hb01 60.0 60.0 1 * -1.13.11.2 2,3-dihydroxybiphenyl pseudomonas sp. hb01 200.0 200.0 1 * -1.13.11.2 3,5-dimethylcatechol stutzerimonas stutzeri 0.66 0.51 2 PMID:16734718 -1.13.11.2 3-ethylcatechol halalkalibacterium ligniniphilum 0.47 0.47 1 PMID:34907211 -1.13.11.2 3-methylcatechol escherichia coli 190.0 190.0 1 PMID:7744021 -1.13.11.2 3-methylcatechol halalkalibacterium ligniniphilum 0.2 0.2 1 PMID:34907211 -1.13.11.2 3-methylcatechol pseudomonas putida 490.0 490.0 1 PMID:7744021 -1.13.11.2 3-methylcatechol pseudomonas sp. 25.0 21.0 2 PMID:15583170 -1.13.11.2 3-methylcatechol pseudomonas sp. ha10 200.0 200.0 1 PMID:28847603 -1.13.11.2 3-methylcatechol pseudomonas sp. hb01 150.0 150.0 1 * -1.13.11.2 3-methylcatechol saccharolobus solfataricus 5.2 2.89 2 PMID:15921893 -1.13.11.2 3-methylcatechol stutzerimonas stutzeri 118.0 118.0 1 PMID:16734718 -1.13.11.2 4-chlorocatechol pseudomonas sp. 45.0 31.0 2 PMID:15583170 -1.13.11.2 4-methylcatechol escherichia coli 930.0 930.0 1 PMID:7744021 -1.13.11.2 4-methylcatechol pseudomonas putida 930.0 930.0 1 PMID:7744021 -1.13.11.2 4-methylcatechol pseudomonas sp. 64.0 58.5 2 PMID:15583170 -1.13.11.2 4-methylcatechol saccharolobus solfataricus 4.7 2.73 2 PMID:15921893 -1.13.11.2 catechol acinetobacter sp. 31.3 31.3 1 PMID:17617714 -1.13.11.2 catechol escherichia coli 690.0 690.0 1 PMID:7744021 -1.13.11.2 catechol pseudomonas putida 930.0 930.0 1 PMID:7744021 -1.13.11.2 catechol pseudomonas sp. 493.0 138.0 4 PMID:12519074;PMID:15583170 -1.13.11.2 catechol pseudomonas sp. ha10 400.0 400.0 1 PMID:28847603 -1.13.11.2 catechol pseudomonas sp. hb01 360.0 360.0 1 * -1.13.11.2 catechol saccharolobus solfataricus 7.8 4.55 2 PMID:15921893 -1.13.11.2 catechol sphingomonas sp. 238.0 193.0 2 PMID:12519074 -1.13.11.2 catechol stutzerimonas stutzeri 200.0 190.0 2 PMID:15347689;PMID:16734718 -1.13.11.20 3-mercaptopropanoate cupriavidus necator 0.01 0.01 1 PMID:26590284 -1.13.11.20 3-mercaptopropanoate pseudomonas aeruginosa 0.033 0.021 7 PMID:26272617;PMID:26878277 -1.13.11.20 3-mercaptopropionate cupriavidus necator 0.82 0.82 1 PMID:26590284 -1.13.11.20 cysteamine azotobacter vinelandii 0.29 0.29 1 PMID:26624219 -1.13.11.20 l-cysteine azotobacter vinelandii 1.2 1.2 1 PMID:26624219 -1.13.11.20 l-cysteine bacillus cereus 2.0 2.0 1 PMID:16855246 -1.13.11.20 l-cysteine bacillus subtilis 0.39 0.39 1 PMID:16855246 -1.13.11.20 l-cysteine cupriavidus necator 0.25 0.13 2 PMID:26590284 -1.13.11.20 l-cysteine homo sapiens 10.35 6.0249999999999995 2 PMID:17135237;PMID:25261132 -1.13.11.20 l-cysteine mus musculus 3.6 2.7 2 PMID:16492780 -1.13.11.20 l-cysteine rattus norvegicus 0.62 0.25 5 PMID:16325423;PMID:16855246;PMID:25390690 -1.13.11.20 l-cysteine streptomyces coelicolor 0.33 0.315 2 PMID:16855246 -1.13.11.20 n-terminal cys of rgs4 homo sapiens 20.1 20.1 1 PMID:31273118 -1.13.11.20 n-terminal cys of rgs5 homo sapiens 16.9 16.9 1 PMID:31273118 -1.13.11.20 o2 homo sapiens 56.6 48.900000000000006 2 PMID:31273118 -1.13.11.24 fisetin penicillium olsonii 56.7 56.7 1 PMID:18206655 -1.13.11.24 galangin penicillium olsonii 33.3 33.3 1 PMID:18206655 -1.13.11.24 kaempferol penicillium olsonii 466.7 466.7 1 PMID:18206655 -1.13.11.24 o2 streptomyces sp. 19.0 15.75 2 PMID:18950192 -1.13.11.24 quercetin bacillus subtilis 25.0 6.7 3 PMID:16411777 -1.13.11.24 quercetin penicillium olsonii 166.7 166.7 1 PMID:18206655 -1.13.11.24 quercetin streptomyces sp. 40.1 7.6 3 PMID:17516049;PMID:18950192 -1.13.11.27 (4-hydroxyphenyl)-pyruvate streptomyces avermitilis 6.8 6.8 1 PMID:12590595 -1.13.11.27 4-hydroxyphenylpyruvate arabidopsis thaliana 4.25 1.079 5 PMID:16681377;PMID:21613226;PMID:30945368;PMID:31027586;PMID:31549053 -1.13.11.27 4-hydroxyphenylpyruvate avena sativa 7.27 7.27 1 PMID:31027586 -1.13.11.27 4-hydroxyphenylpyruvate homo sapiens 3.7 2.2 3 PMID:23950902;PMID:31722428;PMID:34047349 -1.13.11.27 4-hydroxyphenylpyruvate picrophilus oshimae 9.9 9.9 1 PMID:24794033 -1.13.11.27 4-hydroxyphenylpyruvate sphingobium sp. 15.0 15.0 1 PMID:31884791 -1.13.11.27 4-hydroxyphenylpyruvate streptomyces avermitilis 6.8 6.8 1 PMID:21815644 -1.13.11.27 4-hydroxyphenylpyruvate zea mays 0.51 0.51 1 PMID:30945368 -1.13.11.3 3,4-dihydroxybenzoate acinetobacter sp. 120.0 120.0 1 PMID:15487948 -1.13.11.3 3,4-dihydroxybenzoate aspergillus niger 3.9 3.9 1 PMID:31540981 -1.13.11.3 3,4-dihydroxybenzoate brevibacterium fuscum 417.0 417.0 1 PMID:2280720;PMID:6323474 -1.13.11.3 3,4-dihydroxybenzoate buttiauxella sp. s19-1 0.13 0.13 1 PMID:34678927 -1.13.11.3 3,4-dihydroxybenzoate pseudomonas aeruginosa 758.0 758.0 1 PMID:4967959 -1.13.11.3 3,4-dihydroxybenzoate pseudomonas putida 68.0 4.3 3 PMID:15487948;PMID:27721429 -1.13.11.3 3,4-dihydroxybenzoate rhizobium sp. lmb-1 15.97 13.11 2 PMID:28516418 -1.13.11.3 4-sulfocatechol agrobacterium tumefaciens 14.6 14.6 1 PMID:8772173 -1.13.11.3 o2 acinetobacter sp. 120.0 120.0 1 PMID:15487948 -1.13.11.3 o2 brevibacterium fuscum 69.5 69.5 1 PMID:2280720 -1.13.11.3 o2 pseudomonas putida 68.0 68.0 1 PMID:15487948 -1.13.11.3 protocatechuate agrobacterium tumefaciens 89.5 54.15 2 PMID:8772173 -1.13.11.3 protocatechuate pseudomonas putida 100.0 70.0 5 PMID:16101286;PMID:6273403;PMID:9485360 -1.13.11.31 4z,7z,10z,12e,16z,19z-docosahexaenoic acid homo sapiens 13.0 7.7 2 PMID:32324389 -1.13.11.31 5,8,11,14,17-eicosapentaenoic acid myxococcus fulvus 0.031 0.031 1 PMID:30560563 -1.13.11.31 5s,15s-dihydroperoxyeicosatetraenoic acid homo sapiens 0.13 0.13 1 PMID:30407793 -1.13.11.31 5s-hydroperoxy-6e,8z,10e,14z-eicosatetraenoic acid homo sapiens 1.8 0.9440000000000001 2 PMID:33048542 -1.13.11.31 5s-hydroxy-6e,8z,10e,14z-eicosatetraenoic acid homo sapiens 9.7 5.3999999999999995 2 PMID:33048542 -1.13.11.31 arachidonate homo sapiens 46.0 10.0 9 PMID:12731864;PMID:15496467;PMID:32324389;PMID:33048542;PMID:33635645 -1.13.11.31 arachidonic acid homo sapiens 20.0 10.7 2 PMID:19469483 -1.13.11.31 linoleic acid oryctolagus cuniculus 47.23 45.715 2 PMID:21875687;PMID:22189720 -1.13.11.31 o2 homo sapiens 13.1 13.1 1 PMID:12731864 -1.13.11.31 o2 oryctolagus cuniculus 13.7 13.7 1 PMID:17675410 -1.13.11.33 (16(s),5z,8z,11z,14z)-16-hydroxyeicosa-5,8,11,14-tetraenoic acid oryctolagus cuniculus 0.51 0.51 1 PMID:15595827 -1.13.11.33 (17(r),5z,8z,11z,14z)-17-hydroxyeicosa-5,8,11,14-tetraenoic acid oryctolagus cuniculus 0.18 0.18 1 PMID:15595827 -1.13.11.33 (17(s),5z,8z,11z,14z)-17-hydroxyeicosa-5,8,11,14-tetraenoic acid oryctolagus cuniculus 1.24 1.24 1 PMID:15595827 -1.13.11.33 4z,7z,10z,12e,16z,19z-docosahexaenoic acid homo sapiens 13.0 7.7 2 PMID:32324389 -1.13.11.33 5s,15s-dihydroperoxyeicosatetraenoic acid homo sapiens 4.6 4.6 1 PMID:30407793 -1.13.11.33 5s-hydroperoxy-6e,8z,10e,14z-eicosatetraenoic acid homo sapiens 2.0 1.8 3 PMID:33048542 -1.13.11.33 5s-hydroxy-6e,8z,10e,14z-eicosatetraenoic acid homo sapiens 9.7 2.1 3 PMID:33048542 -1.13.11.33 arachidonate homo sapiens 18.0 7.65 6 PMID:15496467;PMID:32324389;PMID:33048542 -1.13.11.33 arachidonate pseudomonas aeruginosa 181.0 157.0 3 PMID:27226387 -1.13.11.33 arachidonic acid glycine max 97.0 97.0 1 PMID:18793849 -1.13.11.33 arachidonic acid homo sapiens 9.93 1.0 11 PMID:18547056;PMID:19645454 -1.13.11.33 arachidonic acid oryctolagus cuniculus 8.16 8.16 1 PMID:15595827 -1.13.11.33 linoleic acid homo sapiens 17.8 10.2 3 PMID:12731864;PMID:18684974 -1.13.11.33 linoleic acid pseudomonas aeruginosa 8.0 8.0 1 PMID:27226387 -1.13.11.33 o2 homo sapiens 7.6 5.6 5 PMID:12731864;PMID:19469483 -1.13.11.33 o2 oryctolagus cuniculus 13.7 13.7 1 PMID:17675410 -1.13.11.34 7,7-d2-arachidonate homo sapiens 0.01 0.0055 2 PMID:27363940 -1.13.11.34 arachidonate homo sapiens 1.2 0.06 3 PMID:27363940;PMID:33048542 -1.13.11.34 arachidonic acid solanum tuberosum 25.0 25.0 1 * -1.13.11.34 linoleic acid solanum tuberosum 138.0 138.0 1 * -1.13.11.36 catechol phenylobacterium immobile 13.3 13.3 1 PMID:6811270 -1.13.11.37 6-chlorohydroxyquinol streptomyces rochei 72.3 72.3 1 PMID:7798136 -1.13.11.37 benzene-1,2,4-triol pimelobacter simplex 29.0 29.0 1 PMID:15772073 -1.13.11.37 hydroxyquinol burkholderia cepacia 6.35 6.35 1 PMID:8900023 -1.13.11.37 hydroxyquinol streptomyces rochei 11.4 11.4 1 PMID:7798136 -1.13.11.38 1-hydroxy-2-naphthoate nocardioides sp. 114.0 114.0 2 PMID:9335300;PMID:9525941 -1.13.11.38 1-hydroxy-2-naphthoate pseudaminobacter salicylatoxidans 44.0 34.0 2 PMID:11698383;PMID:22960182 -1.13.11.38 1-hydroxy-2-naphthoate pseudomonas sp. 70.4 70.4 1 PMID:19574301 -1.13.11.39 2'-chloro-2,3-dihydroxybiphenyl rhodococcus globerulus 7.5 3.5 3 PMID:12700274 -1.13.11.39 2,3-dihydroxybiphenyl dyella ginsengisoli 84.1 84.1 1 PMID:19187202 -1.13.11.39 2,3-dihydroxybiphenyl rhodococcus globerulus 16.5 9.8 3 PMID:12700274 -1.13.11.39 2,3-dihydroxybiphenyl rhodococcus pyridinivorans 40.0 17.0 3 PMID:18585431 -1.13.11.39 3'-chloro-2,3-dihydroxybiphenyl rhodococcus globerulus 12.0 8.5 3 PMID:12700274 -1.13.11.39 3-chlorocatechol rhodococcus pyridinivorans 15.0 9.0 3 PMID:18585431 -1.13.11.39 3-formylcatechol pseudomonas sp. 0.8 0.8 1 PMID:16169514 -1.13.11.39 3-methylcatechol achromobacter sp. 21.63 12.02 3 PMID:23948567 -1.13.11.39 3-methylcatechol dyella ginsengisoli 16.0 16.0 1 PMID:19187202 -1.13.11.39 3-methylcatechol rhodococcus globerulus 13.6 9.8 3 PMID:12700274 -1.13.11.39 3-methylcatechol rhodococcus pyridinivorans 14.0 8.0 3 PMID:18585431 -1.13.11.39 3-methylcatechol uncultured bacterium 44.0 44.0 1 PMID:21898128 -1.13.11.39 4'-chloro-2,3-dihydroxybiphenyl rhodococcus globerulus 18.8 8.3 3 PMID:12700274 -1.13.11.39 4-chlorocatechol dyella ginsengisoli 1.0 1.0 1 PMID:19187202 -1.13.11.39 4-methylcatechol achromobacter sp. 43.2 3.25 3 PMID:23948567 -1.13.11.39 4-methylcatechol dyella ginsengisoli 0.7 0.7 1 PMID:19187202 -1.13.11.39 4-methylcatechol rhodococcus globerulus 0.36 0.24 3 PMID:12700274 -1.13.11.39 4-methylcatechol rhodococcus pyridinivorans 2.0 1.0 3 PMID:18585431 -1.13.11.39 biphenyl-2,3-diol achromobacter sp. 86.32 53.83 3 PMID:23948567 -1.13.11.39 biphenyl-2,3-diol dyella ginsengisoli 79.65 50.14 2 * -1.13.11.39 biphenyl-2,3-diol pseudomonas sp. 115.0 115.0 1 PMID:16169514 -1.13.11.39 biphenyl-2,3-diol pseudomonas sp. ha10 250.0 250.0 1 PMID:28847603 -1.13.11.39 biphenyl-2,3-diol uncultured bacterium 165.0 165.0 1 PMID:21898128 -1.13.11.39 catechol achromobacter sp. 52.56 9.87 3 PMID:23948567 -1.13.11.39 catechol dyella ginsengisoli 6.7 6.7 1 PMID:19187202 -1.13.11.39 catechol pseudomonas sp. 32.5 32.5 1 PMID:16169514 -1.13.11.39 catechol rhodococcus globerulus 0.92 0.468 2 PMID:12700274 -1.13.11.39 catechol rhodococcus pyridinivorans 50.0 24.0 3 PMID:18585431 -1.13.11.39 catechol uncultured bacterium 38.0 38.0 1 PMID:21898128 -1.13.11.4 1-hydroxy 2 naphthoate xanthobacter polyaromaticivorans 6.08 3.3225 2 PMID:17213679 -1.13.11.4 1-hydroxy-2-naphthoate pseudaminobacter salicylatoxidans 44.0 44.0 1 PMID:11698383 -1.13.11.4 1-hydroxynaphthalene-2-carboxylic acid pseudaminobacter salicylatoxidans 24.0 24.0 1 PMID:23384287 -1.13.11.4 2,5-dihydroxybenzoate martelella sp. ad-3 161.29 161.29 1 PMID:26394696 -1.13.11.4 2,5-dihydroxybenzoate rhizorhabdus dicambivorans 0.37 0.37 1 PMID:32786824 -1.13.11.4 2,5-dihydroxybenzoate xanthobacter polyaromaticivorans 5.5 5.5 1 PMID:17213679 -1.13.11.4 3-aminosalicylate pseudaminobacter salicylatoxidans 4.0 4.0 1 PMID:15220336 -1.13.11.4 3-bromosalicylate pseudaminobacter salicylatoxidans 0.3 0.3 1 PMID:15220336 -1.13.11.4 3-chlorogentisate rhizorhabdus dicambivorans 10.33 10.33 1 PMID:32786824 -1.13.11.4 3-chlorosalicylate pseudaminobacter salicylatoxidans 0.4 0.4 1 PMID:15220336 -1.13.11.4 3-hydroxysalicylate pseudaminobacter salicylatoxidans 0.5 0.5 1 PMID:15220336 -1.13.11.4 3-methylsalicylate pseudaminobacter salicylatoxidans 2.9 2.9 1 PMID:15220336 -1.13.11.4 4-aminosalicylate pseudaminobacter salicylatoxidans 0.2 0.2 1 PMID:15220336 -1.13.11.4 4-chlorosalicylate pseudaminobacter salicylatoxidans 0.8 0.8 1 PMID:15220336 -1.13.11.4 4-hydroxysalicylate pseudaminobacter salicylatoxidans 0.2 0.2 1 PMID:15220336 -1.13.11.4 4-methylsalicylate pseudaminobacter salicylatoxidans 0.3 0.3 1 PMID:15220336 -1.13.11.4 5-aminosalicylate pseudaminobacter salicylatoxidans 59.3 59.0 3 PMID:11698383;PMID:15220336;PMID:23384287 -1.13.11.4 5-chlorosalicylate pseudaminobacter salicylatoxidans 0.5 0.5 1 PMID:15220336 -1.13.11.4 5-fluorosalicylate pseudaminobacter salicylatoxidans 3.6 3.0 2 PMID:15220336;PMID:23384287 -1.13.11.4 5-methylsalicylate pseudaminobacter salicylatoxidans 14.3 8.200000000000001 2 PMID:15220336;PMID:23384287 -1.13.11.4 gentisate comamonas testosteroni 642.0 642.0 1 PMID:2156846 -1.13.11.4 gentisate delftia acidovorans 328.0 328.0 1 PMID:2156846;PMID:2280694 -1.13.11.4 gentisate pseudaminobacter salicylatoxidans 225.0 133.0 3 PMID:11698383;PMID:15220336;PMID:23384287 -1.13.11.4 salicylate pseudaminobacter salicylatoxidans 2.3 1.0 3 PMID:11698383;PMID:15220336;PMID:23384287 -1.13.11.40 (15s)-hydroperoxyeicosatetraenoic acid mus musculus 1.5 1.5 1 PMID:16112079 -1.13.11.40 (15s)-hydroxyeicosatetraenoic acid mus musculus 1.0 1.0 1 PMID:16112079 -1.13.11.40 (8r)-8-hydroperoxy-5,9,11,14-eicosatetraenoic acid mus musculus 7.0 7.0 1 PMID:16112079 -1.13.11.40 (8s)-hydroxyeicosatetraenoic acid mus musculus 3.5 3.5 1 PMID:16112079 -1.13.11.40 arachidonate plexaura homomalla 210.0 206.0 3 PMID:15496467;PMID:19594169;PMID:25231982 -1.13.11.40 arachidonic acid mus musculus 3.2 3.2 1 PMID:16112079 -1.13.11.40 arachidonic acid plexaura homomalla 66.7 43.0 2 PMID:8702854 -1.13.11.45 alpha-linolenic acid gaeumannomyces graminis 40.0 40.0 1 PMID:9582345 -1.13.11.45 linoleate gaeumannomyces graminis 40.0 40.0 1 PMID:18024999 -1.13.11.45 linoleic acid gaeumannomyces graminis 18.3 18.3 1 PMID:9582345 -1.13.11.45 linolenate fusarium oxysporum 0.0122 0.0122 1 PMID:26113537 -1.13.11.45 o2 gaeumannomyces graminis 23.3 23.3 1 PMID:9582345 -1.13.11.46 2-oxo-4-phenylbutanoic acid streptomyces coelicolor 0.17 0.17 1 PMID:23935907 -1.13.11.46 4-fluorophenylpyruvic acid streptomyces coelicolor 0.077 0.077 1 PMID:23935907 -1.13.11.46 4-hydroxyphenylpyruvate amycolatopsis orientalis 3.7 3.7 1 PMID:21815644 -1.13.11.46 4-hydroxyphenylpyruvate streptomyces coelicolor 4.5 4.5 1 PMID:23935907 -1.13.11.46 4-methoxyphenylpyruvic acid streptomyces coelicolor 0.96 0.96 1 PMID:23935907 -1.13.11.46 4-methylphenylpyruvic acid streptomyces coelicolor 0.13 0.13 1 PMID:23935907 -1.13.11.46 4-nitrophenylpyruvic acid streptomyces coelicolor 0.035 0.035 1 PMID:23935907 -1.13.11.46 phenylpyruvic acid streptomyces coelicolor 0.88 0.88 1 PMID:23935907 -1.13.11.47 1h-3-hydroxy-4-oxoquinaldine paenarthrobacter nitroguajacolicus 38.4 29.5 3 PMID:20080731;PMID:24482238 -1.13.11.47 1h-3-hydroxy-4-oxoquinoline pseudomonas putida 20.6 20.6 1 PMID:20080731 -1.13.11.48 1h-3-hydroxy-4-oxoquinaldine paenarthrobacter nitroguajacolicus 22.9 22.9 1 PMID:16187153 -1.13.11.48 3-hydroxy-2-methyl-1h-quinolin-4-one paenarthrobacter ilicis 145.0 90.0 2 PMID:15533053 -1.13.11.48 o2 paenarthrobacter nitroguajacolicus 113.7 77.85 2 PMID:16187153 -1.13.11.49 chloride dechloromonas aromatica (nom. nud.) 23000.0 23000.0 1 PMID:29406727 -1.13.11.49 chloride klebsiella pneumoniae 2600.0 2600.0 1 PMID:29406727 -1.13.11.49 chlorite cyanothece sp. pcc 7425 1144.0 267.9 4 PMID:25732258;PMID:33586945 -1.13.11.49 chlorite dechloromonas agitata 7550.0 7550.0 1 PMID:18422344 -1.13.11.49 chlorite dechloromonas aromatica (nom. nud.) 200000.0 200000.0 1 PMID:22304240 -1.13.11.49 chlorite ideonella dechloratans 1800.0 1800.0 1 PMID:11472023 -1.13.11.49 chlorite klebsiella pneumoniae 1900.0 1900.0 1 PMID:25437493 -1.13.11.49 chlorite nitrobacter winogradskyi 190.0 190.0 1 PMID:21441524 -1.13.11.49 chlorite nitrospira defluvii 960.0 43.0 3 PMID:18459973;PMID:20600954;PMID:24754261 -1.13.11.5 3-chlorohomogentisate homo sapiens 0.53 0.53 1 PMID:15479158 -1.13.11.5 3-methylhomogentisate homo sapiens 5.3 5.3 1 PMID:15479158 -1.13.11.5 homogentisate homo sapiens 64.3 42.45 6 PMID:15479158 -1.13.11.5 homogentisate pseudomonas putida 79.5 79.5 1 PMID:23858455 -1.13.11.50 1,1,1-trifluoro-2,4-pentanedione acinetobacter johnsonii 0.0049 0.0049 1 PMID:16131208 -1.13.11.50 1,1,1-trifluoro-pentane-2,4-dione acinetobacter johnsonii 6.6 3.3021499999999997 2 PMID:20050606 -1.13.11.50 1,1-difluoro-2,4-pentanedione acinetobacter johnsonii 0.036 0.036 1 PMID:16131208 -1.13.11.50 1,1-difluoropentane-2,4-dione acinetobacter johnsonii 0.036 0.036 1 PMID:22526564 -1.13.11.50 4,4-difluoro-1-phenyl-1,3-butanedione acinetobacter johnsonii 0.00043 0.00043 1 PMID:16131208 -1.13.11.50 acetylacetate acinetobacter johnsonii 8.5 8.5 1 PMID:15934927 -1.13.11.50 pentane-2,4-dione acinetobacter johnsonii 8.5 6.6 6 PMID:16131208;PMID:22526564 -1.13.11.52 1-methyl-d-tryptophan homo sapiens 0.095 0.0501 2 PMID:24875753 -1.13.11.52 1-methyl-l-tryptophan homo sapiens 0.064 0.062 3 PMID:19737010;PMID:24875753 -1.13.11.52 5-fluoro-dl-tryptophan homo sapiens 0.76 0.4045 2 PMID:24875753 -1.13.11.52 5-fluoro-dl-tryptophan xanthomonas campestris 2.4 2.4 2 PMID:17197414;PMID:18783250 -1.13.11.52 5-fluoro-tryptophan homo sapiens 0.76 0.47 2 PMID:18370401 -1.13.11.52 5-hydroxy-d-tryptophan oryctolagus cuniculus 0.00967 0.00967 1 PMID:26687 -1.13.11.52 5-hydroxy-l-tryptophan homo sapiens 0.065 0.045 2 PMID:10833386;PMID:24875753 -1.13.11.52 5-hydroxy-l-tryptophan oryctolagus cuniculus 0.0433 0.0433 1 PMID:26687 -1.13.11.52 5-hydroxy-tryptophan homo sapiens 0.025 0.025 1 PMID:18370401 -1.13.11.52 5-methoxy-dl-tryptophan homo sapiens 0.161 0.161 1 PMID:24875753 -1.13.11.52 5-methyl-dl-tryptophan homo sapiens 3.78 2.07 2 PMID:24875753 -1.13.11.52 5-methyl-dl-tryptophan xanthomonas campestris 3.59 3.59 1 PMID:18783250 -1.13.11.52 5-methyl-tryptophan homo sapiens 3.78 3.78 1 PMID:18370401 -1.13.11.52 6-fluoro-dl-tryptophan xanthomonas campestris 37.3 37.3 2 PMID:17197414;PMID:18783250 -1.13.11.52 6-methyl-dl-tryptophan homo sapiens 0.108 0.108 1 PMID:24875753 -1.13.11.52 6-methyl-dl-tryptophan xanthomonas campestris 41.0 41.0 1 PMID:18783250 -1.13.11.52 d-trp homo sapiens 2.07 2.07 1 PMID:10833386 -1.13.11.52 d-trp oryctolagus cuniculus 1.18 1.18 1 PMID:26687 -1.13.11.52 d-tryptophan homo sapiens 5.9 1.4500000000000002 6 PMID:18027945;PMID:18370401;PMID:19737010;PMID:22082147;PMID:24875753 -1.13.11.52 d-tryptophan micromonospora sp. 0.0068 0.0068 1 PMID:18493661 -1.13.11.52 indole micromonospora sp. 0.248 0.248 1 PMID:18493661 -1.13.11.52 kynurenine mus musculus 0.002 0.00175 2 PMID:2419335 -1.13.11.52 l-trp homo sapiens 1.55 1.55 1 PMID:10833386 -1.13.11.52 l-trp oryctolagus cuniculus 1.65 1.65 1 PMID:3298973 -1.13.11.52 l-trp xanthomonas campestris 19.5 19.5 1 PMID:17197414 -1.13.11.52 l-tryptophan anopheles gambiae 2.03 2.03 1 PMID:18687401 -1.13.11.52 l-tryptophan blepharisma stoltei 6.5 3.985 2 PMID:29288638 -1.13.11.52 l-tryptophan danio rerio 2.6 2.6 1 PMID:19402226 -1.13.11.52 l-tryptophan homo sapiens 12.0 2.9850000000000003 24 PMID:18027945;PMID:18370401;PMID:19218188;PMID:19290871;PMID:19737010;PMID:20178337;PMID:21835273;PMID:22082147;PMID:24875753;PMID:27112409 -1.13.11.52 l-tryptophan micromonospora sp. 0.045 0.045 1 PMID:18493661 -1.13.11.52 l-tryptophan monodelphis domestica 19.0 9.95 2 PMID:19402226 -1.13.11.52 l-tryptophan mus musculus 16.8 9.3 2 PMID:19402226 -1.13.11.52 l-tryptophan ornithorhynchus anatinus 4.3 3.5999999999999996 2 PMID:19402226 -1.13.11.52 l-tryptophan xanthomonas campestris 35.4 27.45 2 PMID:18783250 -1.13.11.52 l-tryptophan xenopus laevis 2.2 2.2 1 PMID:19402226 -1.13.11.52 o2 homo sapiens 2.9 2.9 1 PMID:19737010 -1.13.11.52 o2 xanthomonas campestris 35.4 35.4 1 PMID:17197414 -1.13.11.52 serotonin micromonospora sp. 0.028 0.028 1 PMID:18493661 -1.13.11.52 serotonin oryctolagus cuniculus 0.00283 0.00283 1 PMID:26687 -1.13.11.52 tryptamine oryctolagus cuniculus 0.00483 0.00483 1 PMID:26687 -1.13.11.53 (1z)-1,2-dihydroxyhex-1-en-3-one mus musculus 17.1 12.485000000000001 2 PMID:26858196 -1.13.11.53 1,2-dihydroxy-3-keto-1-hexene klebsiella pneumoniae 500.0 500.0 1 PMID:11371200 -1.13.11.53 o2 klebsiella pneumoniae 500.0 500.0 1 PMID:11371200 -1.13.11.54 (1z)-1,2-dihydroxyhex-1-en-3-one mus musculus 111.7 111.7 1 PMID:26858196 -1.13.11.54 1,2-dihydroxy-3-oxopent-1-ene oryza sativa 11.7 11.7 1 PMID:16297065 -1.13.11.54 1,2-dihydroxyhex-1-en-3-one klebsiella pneumoniae 260.0 260.0 1 PMID:11371200 -1.13.11.54 o2 klebsiella pneumoniae 260.0 260.0 1 PMID:11371200 -1.13.11.54 o2 oryza sativa 11.8 11.8 1 PMID:16297065 -1.13.11.55 sulfur acidianus ambivalens 2.2 1.1500000000000001 2 PMID:15030315 -1.13.11.57 gallate sphingobium sp. syk-6 316.0 166.9 2 PMID:30346405 -1.13.11.58 9e,11z,14z-20:3omega6 homo sapiens 1.6 1.6 1 PMID:20921226 -1.13.11.58 alpha-linolenic acid myxococcus xanthus 1.27 1.27 1 PMID:30808175 -1.13.11.58 arachidonate capsicum annuum 1.3 1.3 1 PMID:19939946 -1.13.11.58 gamma-linolenic acid myxococcus xanthus 0.81 0.81 1 PMID:30808175 -1.13.11.58 linoleate arabidopsis thaliana 310.0 310.0 1 PMID:18795358 -1.13.11.58 linoleate capsicum annuum 8.7 8.7 1 PMID:19939946 -1.13.11.58 linoleate solanum lycopersicum 390.0 390.0 1 PMID:18795358 -1.13.11.58 linoleic acid myxococcus xanthus 7.95 7.95 1 PMID:30808175 -1.13.11.6 3-hydroxyanthranilate cupriavidus metallidurans 25.0 25.0 1 PMID:15909978 -1.13.11.60 (11z)-icos-11-enoic acid aspergillus nidulans 5.9 5.9 1 PMID:19286665 -1.13.11.60 (8r,9z,12z)-8-hydroperoxyoctadeca-9,12-dienoate colletotrichum gloeosporioides 35.0 35.0 1 PMID:26577673 -1.13.11.60 alpha-linolenate colletotrichum gloeosporioides 25.2 25.1 3 PMID:26577673 -1.13.11.60 alpha-linolenic acid penicillium oxalicum 4.34 4.34 1 PMID:30342100 -1.13.11.60 arachidonate colletotrichum gloeosporioides 18.2 18.2 1 PMID:26577673 -1.13.11.60 arachidonic acid colletotrichum gloeosporioides 18.2 18.2 1 PMID:26577673 -1.13.11.60 dihomo-gamma-linolenate colletotrichum gloeosporioides 17.2 17.2 1 PMID:26577673 -1.13.11.60 dihomo-gamma-linolenic acid colletotrichum gloeosporioides 17.2 17.2 1 PMID:26577673 -1.13.11.60 eicosadienoate colletotrichum gloeosporioides 17.7 17.7 1 PMID:26577673 -1.13.11.60 eicosadienoic acid colletotrichum gloeosporioides 17.7 17.7 1 PMID:26577673 -1.13.11.60 eicosenoate colletotrichum gloeosporioides 22.0 22.0 1 PMID:26577673 -1.13.11.60 eicosenoic acid colletotrichum gloeosporioides 22.0 22.0 1 PMID:26577673 -1.13.11.60 linoleate aspergillus nidulans 6.3 6.3 1 PMID:19286665 -1.13.11.60 linoleate colletotrichum gloeosporioides 35.0 20.79 2 PMID:26577673 -1.13.11.60 linoleate gaeumannomyces graminis 15.0 15.0 1 PMID:8662736 -1.13.11.60 linoleic acid penicillium oxalicum 32.8 32.8 1 PMID:30342100 -1.13.11.60 oleate aspergillus nidulans 4.95 4.95 1 PMID:19286665 -1.13.11.60 oleate colletotrichum gloeosporioides 24.7 24.7 3 PMID:26577673 -1.13.11.60 oleic acid penicillium oxalicum 30.4 30.4 1 PMID:30342100 -1.13.11.60 palmitoleate aspergillus nidulans 3.5 3.5 1 PMID:19286665 -1.13.11.60 palmitoleate colletotrichum gloeosporioides 21.2 21.2 3 PMID:26577673 -1.13.11.60 palmitoleic acid penicillium oxalicum 21.4 21.4 1 PMID:30342100 -1.13.11.61 alpha-linolenic acid nostoc sp. 0.13 0.13 1 PMID:26379279 -1.13.11.61 alpha-linolenic acid nostoc sp. pcc 7120 = fachb-418 0.13 0.13 1 * -1.13.11.61 gamma-linolenic acid nostoc sp. 0.097 0.097 1 PMID:26379279 -1.13.11.61 gamma-linolenic acid nostoc sp. pcc 7120 = fachb-418 0.097 0.097 1 * -1.13.11.61 linoleic acid nostoc sp. 5.12 5.12 1 PMID:26379279 -1.13.11.61 linoleic acid nostoc sp. pcc 7120 = fachb-418 5.12 5.12 1 * -1.13.11.63 alpha-carotene galleria mellonella 0.00817 0.00817 1 PMID:19020100 -1.13.11.63 alpha-carotene gallus gallus 0.0083 0.0083 1 PMID:18979213 -1.13.11.63 alpha-carotene uncultured marine bacterium 0.001 0.001 1 PMID:19366683 -1.13.11.63 beta-apo-4'-carotenal gallus gallus 0.015 0.015 1 PMID:18979213 -1.13.11.63 beta-apo-4'-carotenal uncultured marine bacterium 0.01 0.01 1 PMID:19366683 -1.13.11.63 beta-apo-8'-carotenal gallus gallus 0.0183 0.0183 1 PMID:18979213 -1.13.11.63 beta-carotene galleria mellonella 0.00867 0.00867 1 PMID:19020100 -1.13.11.63 beta-carotene gallus gallus 0.0275 0.0275 1 PMID:18979213 -1.13.11.63 beta-carotene homo sapiens 8.5 0.046 3 PMID:11960992;PMID:20221844;PMID:23727499 -1.13.11.63 beta-carotene mus musculus 0.0001 0.0001 1 PMID:11092891 -1.13.11.63 beta-carotene uncultured marine bacterium 0.037 0.037 1 PMID:19366683 -1.13.11.63 beta-cryptoxanthin gallus gallus 0.0333 0.0333 1 PMID:18979213 -1.13.11.63 beta-cryptoxanthin homo sapiens 0.668 0.668 1 PMID:11960992 -1.13.11.63 beta-cryptoxanthin uncultured marine bacterium 0.013 0.013 1 PMID:19366683 -1.13.11.63 gamma-carotene gallus gallus 0.0082 0.0082 1 PMID:18979213 -1.13.11.63 gamma-carotene uncultured marine bacterium 0.0003 0.0003 1 PMID:19366683 -1.13.11.65 3-hydroxy-beta-apo-10'-carotenal mycobacterium tuberculosis 764.3 764.3 1 PMID:20929460 -1.13.11.65 3-hydroxy-beta-apo-8'-carotenal mycobacterium tuberculosis 1308.0 1308.0 1 PMID:20929460 -1.13.11.65 alpha-carotene galleria mellonella 0.0082 0.0082 1 PMID:19020100 -1.13.11.65 apo-8'-carotenal plesiocystis pacifica sir-1 4.9 4.9 1 PMID:22901074 -1.13.11.65 apo-8'-carotenal sphingopyxis alaskensis 4.9 4.9 1 PMID:22901074 -1.13.11.65 beta,beta-carotene galleria mellonella 0.0087 0.0087 1 PMID:19020100 -1.13.11.65 beta-apo-10'-carotenal mycobacterium tuberculosis 561.7 561.7 1 PMID:20929460 -1.13.11.65 beta-apo-8'-carotenal mycobacterium tuberculosis 392.7 392.7 1 PMID:20929460 -1.13.11.66 2,6-dibromohydroquinone sphingobium chlorophenolicum 1.61 1.61 1 PMID:21870805 -1.13.11.66 2,6-dichloro-p-hydroquinone sphingobium chlorophenolicum 2.1 2.1 1 PMID:10600501 -1.13.11.66 2,6-dichlorohydroquinone sphingobium chlorophenolicum 3.05 3.05 1 PMID:21870805 -1.13.11.66 2,6-dimethylhydroquinone sphingobium chlorophenolicum 1.25 1.25 1 PMID:21870805 -1.13.11.66 2-chloro-6-methylhydroquinone sphingobium chlorophenolicum 2.41 2.41 1 PMID:21870805 -1.13.11.66 hydroquinone pseudomonas fluorescens 2.1 2.1 1 PMID:18502867 -1.13.11.66 hydroquinone sphingomonas sp. 13.5 13.5 2 PMID:21906340 -1.13.11.66 o2 sphingobium chlorophenolicum 4.8 1.8 5 PMID:21870805 -1.13.11.67 all-trans-8'-apo-beta-carotenal nitrosotalea devaniterrae 0.11 0.11 1 PMID:32747548 -1.13.11.67 all-trans-beta-apo-8'-carotenol nitrosotalea devaniterrae 0.0025 0.0025 1 PMID:32747548 -1.13.11.71 all-trans-beta-carotene saccharomyces cerevisiae 0.0475 0.0475 1 PMID:26026965 -1.13.11.71 alpha-carotene saccharomyces cerevisiae 0.0392 0.0392 1 PMID:26026965 -1.13.11.71 beta-carotene homo sapiens 0.0053 0.0053 1 PMID:21302131 -1.13.11.71 lutein saccharomyces cerevisiae 0.0167 0.0167 1 PMID:26026965 -1.13.11.72 2-hydroxyethylphosphonate streptomyces viridochromogenes 0.35 0.35 1 PMID:21711001 -1.13.11.73 (r)-2-hydroxyethylphosphonate nitrosopumilus maritimus 0.17 0.17 1 PMID:22957470 -1.13.11.73 (s)-2-hydroxyethylphosphonate nitrosopumilus maritimus 0.17 0.17 1 PMID:22957470 -1.13.11.73 2-hydroxyethylphosphonate nitrosopumilus maritimus 0.18 0.18 1 PMID:22957470 -1.13.11.74 2-aminophenol ectopseudomonas oleovorans 147.0 147.0 1 PMID:8892823 -1.13.11.75 3-hydroxy-beta-apo-10'-carotenal mycobacterium tuberculosis 764.0 764.0 1 PMID:20929460 -1.13.11.75 3-hydroxy-beta-apo-8'-carotenal mycobacterium tuberculosis 1307.0 1307.0 1 PMID:20929460 -1.13.11.75 beta-apo-10'-carotenal mycobacterium tuberculosis 561.0 561.0 1 PMID:20929460 -1.13.11.75 beta-apo-8'-carotenal mycobacterium tuberculosis 392.0 392.0 1 PMID:20929460 -1.13.11.77 alpha-linolenate nostoc punctiforme 31.0 31.0 1 PMID:24659780 -1.13.11.77 linoleate nostoc punctiforme 135.0 135.0 1 PMID:24659780 -1.13.11.77 oleate nostoc punctiforme 178.0 178.0 1 PMID:24659780 -1.13.11.78 (2-amino-1-hydroxyethyl)phosphonate uncultured bacterium hf130_aepn_1 11.0 11.0 1 PMID:24706911 -1.13.11.78 (r)-(2-amino-1-hydroxyethyl)phosphonate uncultured bacterium 6.8 6.8 1 PMID:31046250 -1.13.11.79 fmnh2 sinorhizobium meliloti 0.018 0.018 1 PMID:17377583 -1.13.11.79 nadh sinorhizobium meliloti 0.002 0.002 1 PMID:17377583 -1.13.11.79 nadph sinorhizobium meliloti 0.002 0.002 1 PMID:17377583 -1.13.11.8 3-o-methylgallate sphingobium sp. 7.3 7.3 1 * -1.13.11.8 gallate sphingobium sp. 53.0 53.0 1 * -1.13.11.8 protocatechuate comamonas testosteroni 350.0 350.0 1 PMID:2280721 -1.13.11.8 protocatechuate sphingobium sp. 230.0 216.0 3 PMID:25562402 -1.13.11.80 (3,5-dihydroxyphenyl)acetyl-coa amycolatopsis orientalis 0.17 0.17 1 PMID:11752437 -1.13.11.80 (3,5-dihydroxyphenyl)acetyl-coa streptomyces toyocaensis 0.172 0.05 5 PMID:17507985;PMID:18004875 -1.13.11.80 (3-hydroxyphenyl)acetyl-coa streptomyces toyocaensis 0.222 0.222 1 PMID:18004875 -1.13.11.80 (5-hydroxyphenyl)acetyl-coa streptomyces toyocaensis 0.125 0.125 1 PMID:18004875 -1.13.11.80 phenylacetyl-coa amycolatopsis orientalis 0.017 0.017 1 PMID:11752437 -1.13.11.80 phenylacetyl-coa streptomyces toyocaensis 0.064 0.064 1 PMID:18004875 -1.13.11.81 7,8-dihydroneopterin mycobacterium tuberculosis 0.0011 0.0011 1 PMID:23150985 -1.13.11.82 4'-apo-beta-carotenal novosphingobium aromaticivorans 0.14 0.14 1 PMID:22711425 -1.13.11.82 8'-apo-beta-carotenal novosphingobium aromaticivorans 0.417 0.417 1 PMID:22711425 -1.13.11.82 gamma-carotene novosphingobium aromaticivorans 0.0033 0.0033 1 PMID:22711425 -1.13.11.88 isoeugenol pseudomonas nitroreducens 3.8 2.95 2 PMID:23391906 -1.13.11.88 isoeugenol pseudomonas putida 5.18 5.18 1 PMID:17516050 -1.13.11.88 isoeugenol pseudomonas sp. 4.21 4.21 1 * -1.13.11.89 (1r)-[2-amino-1-hydroxyethyl]phosphonic acid gimesia maris 2.5 2.5 1 PMID:30810303 -1.13.11.89 (hydroxymethyl)phosphonate gimesia maris 0.55 0.55 1 PMID:30810303 -1.13.11.89 (r)-1-hydroxyethylphosphonic acid gimesia maris 1.54 1.54 1 PMID:30810303 -1.13.11.91 3-mercaptopropanoate azotobacter vinelandii 0.94 0.695 2 PMID:26624219;PMID:31750652 -1.13.11.91 3-mercaptopropanoate cupriavidus necator 0.82 0.585 2 PMID:26590284;PMID:31045343 -1.13.11.91 3-mercaptopropanoate pseudomonas aeruginosa 0.28 0.11 11 PMID:26272617;PMID:26878277;PMID:31045343 -1.13.11.92 13-methyltetradecanoic acid crocosphaera subtropica 3.14 3.14 1 * -1.13.11.92 myristic acid crocosphaera subtropica 4.03 4.03 1 * -1.13.11.93 2-oxoadipate pseudomonas putida 5.5 5.5 1 PMID:31064836 -1.13.12.15 3,4-dihydroxy-l-phenylalanine cereibacter sphaeroides 0.68 0.68 1 PMID:18923551 -1.13.12.16 1-nitrobutane neurospora crassa 6.2 5.9 3 PMID:15582992 -1.13.12.16 1-nitrohexane neurospora crassa 1.7 1.5 3 PMID:15582992 -1.13.12.16 1-nitropentane neurospora crassa 4.3 3.65 2 PMID:15582992 -1.13.12.16 1-nitropropane neurospora crassa 1300.0 20.0 5 PMID:15582992;PMID:34655320;PMID:9501443 -1.13.12.16 2-nitropropane neurospora crassa 6400.0 160.0 3 PMID:15582992;PMID:9501443 -1.13.12.16 3-nitropropionate neurospora crassa 4.4 4.4 2 PMID:22464989;PMID:34655320 -1.13.12.16 3-nitropropionic acid neurospora crassa 42.0 42.0 1 PMID:33038312 -1.13.12.16 butyl 1-nitronate neurospora crassa 55.0 55.0 1 PMID:34655320 -1.13.12.16 butyl-1-nitronate neurospora crassa 56.0 55.0 3 PMID:15582992 -1.13.12.16 ethyl nitronate cyberlindnera saturnus 4100.0 440.0 4 PMID:23530838 -1.13.12.16 ethyl nitronate neurospora crassa 2000.0 51.0 7 PMID:15582992;PMID:17105207;PMID:34655320;PMID:9501443 -1.13.12.16 ethylnitronate neurospora crassa 57.0 36.6 2 PMID:15582992;PMID:18690716 -1.13.12.16 ethylnitronate pseudomonas aeruginosa 350.0 350.0 1 PMID:25002579 -1.13.12.16 hexyl 1-nitronate neurospora crassa 22.0 22.0 1 PMID:34655320 -1.13.12.16 hexyl-1-nitronate neurospora crassa 22.0 21.5 2 PMID:15582992 -1.13.12.16 nitroethane neurospora crassa 2000.0 12.5 8 PMID:15582992;PMID:17105207;PMID:34655320;PMID:9501443 -1.13.12.16 pentyl-1-nitronate neurospora crassa 35.0 35.0 1 PMID:15582992 -1.13.12.16 propionate 3-nitronate cyberlindnera saturnus 860.0 830.0 2 PMID:23530838;PMID:29383742 -1.13.12.16 propionate 3-nitronate neurospora crassa 300.0 300.0 1 PMID:33038312 -1.13.12.16 propionate-3-nitronate cyberlindnera saturnus 775.0 775.0 1 PMID:22464989 -1.13.12.16 propionate-3-nitronate neurospora crassa 430.0 430.0 2 PMID:22464989;PMID:34655320 -1.13.12.16 propionate-3-nitronate pseudomonas aeruginosa 1300.0 1300.0 1 PMID:25002579 -1.13.12.16 propyl 1-nitronate neurospora crassa 60.0 60.0 1 PMID:34655320 -1.13.12.16 propyl-1-nitronate neurospora crassa 1300.0 60.0 3 PMID:15582992;PMID:9501443 -1.13.12.16 propyl-1-nitronate pseudomonas aeruginosa 1120.0 1120.0 1 PMID:25002579 -1.13.12.16 propyl-2-nitronate neurospora crassa 6400.0 29.0 3 PMID:15582992;PMID:9501443 -1.13.12.19 2-oxoglutarate pseudomonas syringae 0.5 0.5 1 * -1.13.12.2 l-arginine pseudomonas sp. aiu 813 1.6 1.6 1 PMID:29511608 -1.13.12.2 l-lysine pseudomonas fluorescens 34.7 34.7 1 * -1.13.12.2 l-lysine pseudomonas sp. aiu 813 4.5 4.5 1 PMID:29511608 -1.13.12.2 l-ornithine pseudomonas sp. aiu 813 6.7 6.7 1 PMID:29511608 -1.13.12.22 [4,5-dihydroxy-10-oxo-3-(3-oxobutanoyl)-9,10-dihydroanthracen-2-yl]acetate streptomyces nogalater 1.5 1.45 2 PMID:20052967 -1.13.12.22 dithranol streptomyces nogalater 1.0 0.585 2 PMID:27307041 -1.13.12.22 o2 streptomyces nogalater 1.83 0.9400000000000001 2 PMID:27307041 -1.13.12.3 d,l-3-phenyl-2-hydrazinopropanoic acid pseudomonas savastanoi 1.67e-05 1.67e-05 1 PMID:7840624 -1.13.12.3 d,l-3-pyridylalanine pseudomonas savastanoi 0.00075 0.00075 1 PMID:7840624 -1.13.12.3 d,l-n-methyl-phenylalanine pseudomonas savastanoi 0.000317 0.000317 1 PMID:7840624 -1.13.12.3 l-alanine pseudomonas savastanoi 0.000317 0.000317 1 PMID:7840624 -1.13.12.3 l-methionine pseudomonas savastanoi 0.00155 0.00155 1 PMID:7840624 -1.13.12.3 l-phenylalanine pseudomonas savastanoi 0.00305 0.00305 1 PMID:7840624 -1.13.12.3 l-tryptophan pseudomonas savastanoi 13.2 13.2 3 PMID:14636050;PMID:23521653;PMID:7840624 -1.13.12.3 tryptophan pseudomonas savastanoi 13.2 13.2 1 PMID:14636049 -1.13.12.4 (s)-lactate mycolicibacterium smegmatis 0.0148 0.0148 1 PMID:8663383 -1.13.12.5 benzylluciferin renilla reniformis 1.85 1.85 1 PMID:36127 -1.13.12.5 benzylluciferin methyl ether renilla reniformis 0.983 0.983 1 PMID:36127 -1.13.12.5 coelenterazine renilla sp. 3.9 3.9 1 PMID:16857694 -1.13.12.5 luciferin renilla reniformis 1.85 1.85 1 PMID:12797 -1.13.12.5 methyl luciferin renilla reniformis 0.0167 0.0167 1 PMID:21679 -1.13.12.6 cypridina luciferin apogon ellioti 0.0152 0.0152 1 * -1.13.12.6 cypridina luciferin vargula hilgendorfii 26.7 13.35735 2 * -1.13.12.7 (4s)-2-(6-hydroxy-1,3-benzoxazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid photinus pyralis 0.0018 0.0018 1 PMID:23164087 -1.13.12.7 (4s)-2-(6-hydroxy-1-benzofuran-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid photinus pyralis 0.00063 0.00063 1 PMID:23164087 -1.13.12.7 (4s)-2-(6-hydroxy-1-benzothiophen-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid photinus pyralis 0.0067 0.0067 1 PMID:23164087 -1.13.12.7 (4s)-2-(6-hydroxy-1h-benzimidazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid photinus pyralis 0.00051 0.00051 1 PMID:23164087 -1.13.12.7 d-luciferin photinus pyralis 0.19 0.167 3 PMID:12950169;PMID:15683224;PMID:23164087 -1.13.12.7 d-luciferyl-o-adenosine monophosphate photinus pyralis 0.23 0.23 1 PMID:15683224 -1.13.12.7 lauric acid nipponoluciola cruciata 0.651 0.651 1 PMID:15849423 -1.13.12.7 lauric acid photinus pyralis 0.278 0.278 1 PMID:15849423 -1.13.12.7 linolenic acid photinus pyralis 0.13 0.13 1 PMID:12681517 -1.13.12.7 luciferin photinus pyralis 1.6 1.6 1 PMID:10529195 -1.13.12.7 mgatp2- photinus pyralis 0.167 0.167 1 PMID:15683224 -1.13.12.9 l-phenylalanine pseudomonas sp. 115.0 109.0 2 PMID:15632301;PMID:18417467 -1.13.99.1 inositol rattus norvegicus 7.22 7.22 1 PMID:13630882 -1.13.99.1 myo-inositol mus musculus 76.8 76.8 1 PMID:30125674 -1.13.99.1 myo-inositol sus scrofa 0.183 0.183 1 PMID:11716759 -1.14.11.1 (2s)-3-carboxy-n-(fluoromethyl)-2-hydroxy-n,n-dimethylpropan-1-aminium homo sapiens 0.3 0.3 1 PMID:25030770 -1.14.11.1 (2s)-3-carboxy-n-(fluoromethyl)-2-hydroxy-n,n-dimethylpropan-1-aminium pseudomonas sp. 5.0 5.0 1 PMID:25030770 -1.14.11.1 (3-carboxypropyl)(trimethyl)arsanium pseudomonas sp. 2.61 2.61 1 PMID:26660433 -1.14.11.1 (3-carboxypropyl)(trimethyl)phosphanium pseudomonas sp. 4.13 4.13 1 PMID:26660433 -1.14.11.1 (3r)-3-fluoro-4-(trimethylammonio)butanoate homo sapiens 0.14 0.14 1 PMID:25030770 -1.14.11.1 (3r)-3-fluoro-4-(trimethylammonio)butanoate pseudomonas sp. 0.059 0.059 1 PMID:25030770 -1.14.11.1 (3s)-3-fluoro-4-(trimethylammonio)butanoate homo sapiens 0.62 0.36 2 PMID:22730246 -1.14.11.1 2-oxoglutarate homo sapiens 5.1 1.0750000000000002 4 PMID:22730246;PMID:25030770 -1.14.11.1 2-oxoglutarate pseudomonas sp. 3.5 3.5 1 PMID:25030770 -1.14.11.1 4-(trimethylammonio)butanoic acid homo sapiens 5.3 5.3 1 PMID:22730246 -1.14.11.1 4-trimethylammoniobutanoate homo sapiens 0.83 0.83 1 PMID:25030770 -1.14.11.1 4-trimethylammoniobutanoate pseudomonas sp. 21.3 14.16 2 PMID:25030770;PMID:26660433 -1.14.11.1 gamma-butyrobetaine pseudomonas sp. 34.0 34.0 1 PMID:861203 -1.14.11.11 l-hyoscyamine anisodus acutangulus 1.0 1.0 1 PMID:26239231 -1.14.11.16 2-oxoglutarate homo sapiens 0.19 0.19 1 PMID:32107312 -1.14.11.16 [factor x first egf-like domain]-l-aspartate homo sapiens 1.23 1.23 1 PMID:34543426 -1.14.11.16 [thioether-linked cyclic peptide hfx-cp101-119]-l-aspartate homo sapiens 0.2 0.2 1 PMID:32107312 -1.14.11.16 first growth factor-like domain-l-aspartate bos taurus 0.0317 0.023350000000000003 4 PMID:1856229 -1.14.11.16 o2 homo sapiens 0.23 0.23 1 PMID:32107312 -1.14.11.17 2-oxoglutarate escherichia coli 3.0 1.53 2 PMID:16643838 -1.14.11.17 taurine escherichia coli 3.3 3.15 2 PMID:16643838;PMID:17350690 -1.14.11.2 (pro-pro-gly)10 chlamydomonas reinhardtii 7.0 7.0 1 PMID:19553701 -1.14.11.2 (pro-pro-gly)10 homo sapiens 0.22 0.22 1 PMID:15555944 -1.14.11.2 (ser-pro)5 chlamydomonas reinhardtii 19.0 19.0 1 PMID:19553701 -1.14.11.2 daltllapaagdtiisldyg homo sapiens 0.0103 0.0102 2 PMID:23787140 -1.14.11.2 dansyl-gly-phe-pro-gly-oet homo sapiens 0.15 0.15 1 PMID:15555944 -1.14.11.2 dldlealapyipadddfql homo sapiens 0.02 0.0194 2 PMID:23787140 -1.14.11.2 peg-gly-tyr-4-fluoroproline-glyoet homo sapiens 6.0 5.25 2 PMID:19111518 -1.14.11.2 poly(ethylene glycol)-gly-l-tyr-(2s)-4-thiaproline-gly-och2ch2oh homo sapiens 7.8 7.8 1 PMID:18702512 -1.14.11.2 poly(ethylene glycol)-gly-l-tyr-l-(2s,4s)-4-fluoroproline-gly-och2ch2oh homo sapiens 4.2 4.2 1 PMID:18702512 -1.14.11.2 poly(ethylene glycol)-gly-l-tyr-l-pro-gly-och2ch2oh homo sapiens 6.0 6.0 1 PMID:18702512 -1.14.11.2 poly(l-pro) chlamydomonas reinhardtii 70.0 70.0 1 PMID:17940281 -1.14.11.2 poly(l-proline) chlamydomonas reinhardtii 30.0 30.0 1 PMID:19553701 -1.14.11.2 procollagen l-proline gallus gallus 4.8 4.8 1 PMID:1653613 -1.14.11.2 protocollagen gallus gallus 4.0 4.0 1 PMID:4354367 -1.14.11.2 tert-butyloxycarbonyl-gly-val-pro-gly-val-oh gallus gallus 2.33 2.33 1 PMID:1847136 -1.14.11.2 tert-butyloxycarbonyl-pro-pro-ala-pro-oh gallus gallus 0.11 0.11 1 PMID:1847136 -1.14.11.2 tert-butyloxycarbonyl-pro-pro-gln-pro-och3 gallus gallus 0.07 0.07 1 PMID:1847136 -1.14.11.2 tert-butyloxycarbonyl-pro-pro-gly-pro gallus gallus 0.2 0.2 1 PMID:1847136 -1.14.11.2 tert-butyloxycarbonyl-pro-pro-gly-pro-nhch3 gallus gallus 0.38 0.38 1 PMID:1847136 -1.14.11.2 tert-butyloxycarbonyl-pro-pro-gly-pro-pro-oh gallus gallus 0.79 0.79 1 PMID:1847136 -1.14.11.2 tert-butyloxycarbonyl-val-pro-gly-val-oh gallus gallus 0.88 0.88 1 PMID:1847136 -1.14.11.21 (2s,3r)-proclavaminate streptomyces clavuligerus 0.765 0.765 1 PMID:2207091 -1.14.11.21 n-alpha-acetyl-l-arginine streptomyces clavuligerus 6.4 6.4 1 PMID:8229018 -1.14.11.21 rac-proclavaminate streptomyces clavuligerus 0.725 0.725 1 PMID:2207091 -1.14.11.26 cephalosporin g streptomyces clavuligerus 0.055 0.055 1 PMID:27084018 -1.14.11.26 penicillin g streptomyces clavuligerus 0.0453 0.0453 1 PMID:16332884 -1.14.11.26 penicillin n streptomyces clavuligerus 0.307 0.307 1 PMID:16332884 -1.14.11.28 l-proline streptomyces sp. 3.2 3.2 1 PMID:9294421 -1.14.11.29 2-oxoglutarate homo sapiens 0.038 0.038 1 PMID:25857330 -1.14.11.29 dldlealapyipadddfql homo sapiens 0.032 0.032 1 PMID:25857330 -1.14.11.29 hypoxia-inducible factor1alpha c-terminal oxygen-dependent degradation domain-l-proline homo sapiens 0.0032 0.0022 2 PMID:21410436 -1.14.11.29 hypoxia-inducible factor2alpha c-terminal oxygen-dependent degradation domain-l-proline homo sapiens 0.0005 0.0005 1 PMID:21410436 -1.14.11.29 o2 homo sapiens 0.133 0.133 1 PMID:25857330 -1.14.11.30 desglpqltsydaevnapiqgsrnllqgeellraldqvn homo sapiens 0.55 0.55 1 PMID:27815979 -1.14.11.30 o2 homo sapiens 0.55 0.55 1 PMID:27815979 -1.14.11.31 2-oxoglutarate papaver somniferum 0.0081 0.0081 1 PMID:20228795 -1.14.11.31 oripavine papaver somniferum 0.0191 0.0191 1 PMID:20228795 -1.14.11.31 thebaine papaver somniferum 0.017 0.017 1 PMID:20228795 -1.14.11.32 2-oxoglutarate papaver somniferum 0.011 0.011 1 PMID:20228795 -1.14.11.32 codeine papaver somniferum 0.0161 0.0161 1 PMID:20228795 -1.14.11.32 thebaine papaver somniferum 0.0099 0.0099 1 PMID:20228795 -1.14.11.33 1-methyl-adenine in 5'-daaaa-1mea-yyaaa homo sapiens 0.04 0.04 1 PMID:26967262 -1.14.11.33 1-methyl-damp escherichia coli 0.07 0.07 1 PMID:12944387 -1.14.11.33 1-methyl-datp escherichia coli 0.033 0.033 1 PMID:12944387 -1.14.11.33 2'-deoxy-1-methyl-adenosine 3'-phosphate escherichia coli 0.012 0.012 1 PMID:12944387 -1.14.11.33 3-methylcytosine in 3'-tailed dna homo sapiens 0.076 0.05 2 PMID:31642493 -1.14.11.33 d(tpm1a) escherichia coli 0.06 0.06 1 PMID:12944387 -1.14.11.33 d(tpm1apt) escherichia coli 0.12 0.12 1 PMID:12944387 -1.14.11.33 dna-n1-methyladenine escherichia coli 0.1235 0.1235 1 PMID:24596302 -1.14.11.33 double-stranded dna-1-methyladenine escherichia coli 0.052 0.052 1 PMID:18003660 -1.14.11.33 double-stranded dna-3-methylcytosine escherichia coli 0.055 0.055 1 PMID:18003660 -1.14.11.33 n1-methyl-atp escherichia coli 0.02 0.02 1 PMID:12944387 -1.14.11.33 poly(dm1a) escherichia coli 0.2 0.2 1 PMID:12944387 -1.14.11.33 single-stranded dna-1-methyladenine escherichia coli 0.062 0.062 1 PMID:18003660 -1.14.11.33 single-stranded dna-3-methylcytosine escherichia coli 0.037 0.037 1 PMID:18003660 -1.14.11.35 (+/-)-1-deoxypentalenic acid streptomyces avermitilis 4.2 4.2 1 PMID:16704250 -1.14.11.38 fumitremorgin b aspergillus fumigatus 0.19 0.19 1 PMID:21404415 -1.14.11.39 l-asparagine streptomyces coelicolor 4.98 4.98 1 PMID:17373765 -1.14.11.4 2-oxoglutarate homo sapiens 0.183 0.183 1 PMID:28216326 -1.14.11.4 [procollagen]-l-lysine gallus gallus 4.2 4.2 1 PMID:6779811 -1.14.11.4 peptide (ikg)3 homo sapiens 0.2 0.2 1 PMID:28216326 -1.14.11.41 l-arginine streptomyces vinaceus 43.5 43.5 1 PMID:19490124 -1.14.11.41 l-canavanine streptomyces vinaceus 1.22 1.22 1 PMID:19490124 -1.14.11.41 l-homoarginine streptomyces vinaceus 13.85 13.85 1 PMID:19490124 -1.14.11.43 (s)-2-(4-chloro-2-methylphenoxy)propanoate sphingobium herbicidovorans 16.83 16.83 1 PMID:16731970 -1.14.11.44 (r)-2-(4-chloro-2-methylphenoxy)propanoate sphingobium herbicidovorans 4.2 4.2 1 PMID:16731970 -1.14.11.45 2-oxoglutarate bacillus mycoides 0.577 0.577 1 PMID:29869760 -1.14.11.45 2-oxoglutarate bacillus thuringiensis 0.04 0.04 1 PMID:25725632 -1.14.11.45 l-isoleucine bacillus mycoides 0.481 0.481 1 PMID:29869760 -1.14.11.45 l-isoleucine bacillus thuringiensis 6.0 0.089 3 PMID:22448874;PMID:25725632;PMID:28430004 -1.14.11.45 l-leucine bacillus thuringiensis 7.5 7.5 1 PMID:22448874 -1.14.11.45 l-methionine bacillus thuringiensis 33.0 33.0 1 PMID:22448874 -1.14.11.47 [50s ribosomal cyclic peptide 6kkpaevrmgkgkg88-linker]-l-arg82 rhodothermus marinus 0.47 0.47 1 PMID:29523972 -1.14.11.47 [50s ribosomal peptide kpvtkkpaevrmgkgkgsve-nh2]-l-arg rhodothermus marinus 0.5 0.5 1 PMID:29523972 -1.14.11.48 2-oxoadipate aspergillus nidulans 7.6 7.6 1 PMID:17429948 -1.14.11.48 2-oxoglutarate aspergillus nidulans 67.0 66.5 3 PMID:17429948;PMID:18036331 -1.14.11.48 9-methylxanthine aspergillus nidulans 3.8 3.8 1 PMID:18036331 -1.14.11.48 xanthine aspergillus nidulans 72.0 71.4 3 PMID:17429948;PMID:18036331 -1.14.11.49 2-oxoglutarate streptomyces sp. 1.53 1.53 1 PMID:21216959 -1.14.11.49 ump streptomyces sp. 1.27 1.27 1 PMID:21216959 -1.14.11.52 2-oxoglutarate streptomyces hygroscopicus subsp. limoneus 0.97 0.97 1 PMID:22961651 -1.14.11.52 validamycin a streptomyces hygroscopicus subsp. limoneus 0.97 0.97 1 PMID:22961651 -1.14.11.53 2-oxoglutarate homo sapiens 0.3 0.3 1 PMID:26701100 -1.14.11.53 cccc(m6a)ccccccccc homo sapiens 0.0023 0.0023 1 PMID:27156733 -1.14.11.53 ga(m6a)ca homo sapiens 0.0027 0.0027 1 PMID:27156733 -1.14.11.53 gcgg(m6a)cuccagaug homo sapiens 0.0029 0.0029 1 PMID:27156733 -1.14.11.53 gg(m6a)cu homo sapiens 0.0023 0.0023 1 PMID:27156733 -1.14.11.53 n3-methylthymine in single-stranded dna homo sapiens 0.000117 0.000117 1 PMID:18775698 -1.14.11.53 n3-methylthymine in single-stranded dna mus musculus 0.00148 0.00148 1 PMID:18775698 -1.14.11.53 n3-methyluracil in single-stranded mrna homo sapiens 0.0019 0.0019 1 PMID:18775698 -1.14.11.53 n3-methyluracil in single-stranded mrna mus musculus 0.0033 0.0033 1 PMID:18775698 -1.14.11.53 n6-methyladenine in mrna homo sapiens 0.0029 0.0029 1 PMID:24596302 -1.14.11.54 rna-n1-methyladenine escherichia coli 0.062 0.062 1 PMID:24596302 -1.14.11.54 rna-n6-methyladenine escherichia coli 0.0018 0.0018 1 PMID:24596302 -1.14.11.55 ectoine acidiphilium cryptum 3.4 3.4 1 PMID:24714029 -1.14.11.55 ectoine alkalilimnicola ehrlichii 1.2 1.2 1 PMID:24714029 -1.14.11.55 ectoine halomonas elongata 2.8 1.51 2 PMID:24714029;PMID:31106391 -1.14.11.55 ectoine paenibacillus lautus 1.6 1.6 1 PMID:24714029 -1.14.11.55 ectoine sphingopyxis alaskensis 1.2 1.2 1 PMID:24714029 -1.14.11.55 ectoine streptantibioticus cattleyicolor 0.55 0.55 1 PMID:31106391 -1.14.11.55 ectoine stutzerimonas stutzeri 8.9 8.9 1 PMID:24714029 -1.14.11.55 ectoine virgibacillus salexigens 7.7 7.7 1 PMID:24714029 -1.14.11.55 l-proline halomonas elongata 0.029 0.029 1 PMID:31106391 -1.14.11.55 l-proline streptantibioticus cattleyicolor 0.11 0.11 1 PMID:31106391 -1.14.11.56 l-homophenylalanine sinorhizobium meliloti 0.00025 0.00025 1 * -1.14.11.56 l-proline mesorhizobium loti 24.0 24.0 1 PMID:19133227 -1.14.11.56 l-proline sinorhizobium meliloti 25.0 25.0 1 PMID:19133227 -1.14.11.59 (2r)-4-hydroxy-3-oxo-3,4-dihydro-2h-1,4-benzoxazin-2-yl beta-d-glucopyranoside zea mays 2.1 2.1 1 PMID:18192444 -1.14.11.6 5-formyluracil neurospora crassa 0.765 0.765 1 PMID:26429971 -1.14.11.6 5-formyluracil rhodotorula glutinis 1.13 1.13 1 PMID:19341313 -1.14.11.6 5-hydroxymethyluracil rhodotorula glutinis 0.42 0.42 1 PMID:19341313 -1.14.11.6 5-hydroxyuracil neurospora crassa 0.325 0.325 1 PMID:26429971 -1.14.11.6 n1-methylthymine rhodotorula glutinis 0.43 0.43 1 PMID:19341313 -1.14.11.6 n1-methyluracil rhodotorula glutinis 0.27 0.27 1 PMID:19341313 -1.14.11.6 thymine neurospora crassa 0.416 0.416 1 PMID:26429971 -1.14.11.6 thymine rhodotorula glutinis 16.7 8.91 2 PMID:19341313;PMID:8268182 -1.14.11.60 scopoletin arabidopsis thaliana 1.73 1.73 1 PMID:29361149 -1.14.11.61 trans-feruloyl-coa arabidopsis thaliana 11.0 11.0 1 PMID:18547395 -1.14.11.61 trans-feruloyl-coa ipomoea batatas 2.84 2.76 2 PMID:22169019 -1.14.11.65 [histone h3]-n6,n6-dimethyl-l-lysine9 homo sapiens 0.275 0.275 2 PMID:24214985 -1.14.11.65 [histone h3]-n6-methyl-l-lysine9 homo sapiens 0.282 0.282 2 PMID:24214985 -1.14.11.66 [histone h3, a7h]-n6,n6,n6-trimethyl-l-lysine 9 homo sapiens 0.000183 0.000183 1 PMID:17589523 -1.14.11.66 [histone h3, a7r]-n6,n6,n6-trimethyl-l-lysine 9 homo sapiens 0.000183 0.000183 1 PMID:17589523 -1.14.11.66 [histone h3, g12p]-n6,n6,n6-trimethyl-l-lysine 9 homo sapiens 0.00012 0.00012 1 PMID:17589523 -1.14.11.66 [histone h3]-n6,n6,n6-trimethyl-l-lysine 9 homo sapiens 0.00025 0.00025 1 PMID:17589523 -1.14.11.66 histone h3 n6,n6,n6-trimethyl-l-lysine9 homo sapiens 0.076 0.028 5 PMID:21914792 -1.14.11.66 histone h3 n6,n6-dimethyl-l-lysine9 homo sapiens 0.065 0.0072 5 PMID:21914792 -1.14.11.67 [acetylated histone h3 21mer]-n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.047 0.044 2 PMID:30626866 -1.14.11.67 [acetylated histone h3 21mer]-n6,n6-dimethyl-l-lysine4 homo sapiens 0.023 0.023 2 PMID:30626866 -1.14.11.67 [histone h3 n-terminal 13mer] n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.111 0.111 1 PMID:31985200 -1.14.11.67 [histone h3 n-terminal 18mer mutant k14a/r17a/k18a] n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.108 0.108 1 PMID:31985200 -1.14.11.67 [histone h3 n-terminal 18mer mutant k14ac/k18ac] n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.101 0.101 1 PMID:31985200 -1.14.11.67 [histone h3 n-terminal 18mer] n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.078 0.078 1 PMID:31985200 -1.14.11.67 [histone h3 n-terminal 21mer mutant k9a] n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.061 0.061 1 PMID:31985200 -1.14.11.67 [histone h3 n-terminal 21mer mutant q5a] n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.056 0.056 1 PMID:31985200 -1.14.11.67 [histone h3 n-terminal 21mer mutant r2a] n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.069 0.069 1 PMID:31985200 -1.14.11.67 [histone h3 n-terminal 21mer mutant r8a] n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.054 0.054 1 PMID:31985200 -1.14.11.67 [histone h3 n-terminal 21mer mutant t3a] n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.056 0.056 1 PMID:31985200 -1.14.11.67 [histone h3 n-terminal 21mer mutant t6a] n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.075 0.075 1 PMID:31985200 -1.14.11.67 [histone h3 n-terminal 21mer mutant t6s] n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.07 0.07 1 PMID:31985200 -1.14.11.67 [histone h3 n-terminal 21mer mutant t6v] n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.05 0.05 1 PMID:31985200 -1.14.11.67 [histone h3 n-terminal 21mer] n6,n6,n6-trimethyl-l-lysine4 homo sapiens 0.052 0.052 1 PMID:31985200 -1.14.11.67 [histone h3]-n6,n6-dimethyl-l-lysine4 arabidopsis thaliana 0.0113 0.0085 2 PMID:18393445 -1.14.11.67 [histone h3]-n6-methyl-l-lysine4 arabidopsis thaliana 0.0083 0.0083 1 PMID:18393445 -1.14.11.69 [histone h3]-n6,n6,n6-trimethyl-l-lysine 36 homo sapiens 0.000217 0.000217 1 PMID:17589523 -1.14.11.69 [histone h3]-n6,n6,n6-trimethyllysine36 homo sapiens 0.00022 0.00022 1 PMID:17589523 -1.14.11.70 2-oxoglutarate oscillatoria sp. pcc 7926 0.03 0.03 1 PMID:29653078 -1.14.11.71 2-oxoglutarate gimesia maris 0.42 0.42 1 PMID:30810303 -1.14.11.71 methylphosphonate gimesia maris 0.36 0.36 1 PMID:30810303 -1.14.11.78 (3r)-3-[(e)-(carboxymethylidene)amino]butanoate streptomyces coeruleorubidus 0.365 0.365 1 PMID:35254829 -1.14.11.78 (r)-3-((carboxymethyl)amino)butanoate streptomyces coeruleorubidus 0.365 0.365 1 PMID:29906336 -1.14.11.78 (r)-3-((carboxymethyl)amino)butanoic acid streptomyces coeruleorubidus 0.365 0.365 1 PMID:29906336 -1.14.11.78 2-oxoglutarate streptomyces coeruleorubidus 0.008 0.008 2 PMID:29906336 -1.14.12.10 2-methylbenzoate acinetobacter calcoaceticus 4.2 4.2 1 PMID:12949084 -1.14.12.10 3-chlorobenzoate acinetobacter calcoaceticus 3.0 3.0 1 PMID:12949084 -1.14.12.10 3-methylbenzoate acinetobacter calcoaceticus 7.0 7.0 1 PMID:12949084 -1.14.12.10 benzoate acinetobacter calcoaceticus 8.6 8.6 1 PMID:12949084 -1.14.12.10 benzoate pseudomonas putida 367.0 185.7 2 PMID:26154836;PMID:7372624 -1.14.12.12 biphenyl sphingomonas sp. 1.01 1.01 1 PMID:17014090 -1.14.12.12 naphthalene sphingomonas sp. 1.82 1.82 1 PMID:17014090 -1.14.12.17 nadh escherichia coli 83.0 66.5 2 PMID:10777548 -1.14.12.17 nitric oxide vibrio vulnificus 21.4 15.25 2 PMID:31616401 -1.14.12.17 no escherichia coli 670.0 382.0 2 PMID:10777548 -1.14.12.18 benzene ectopseudomonas oleovorans 0.056 0.056 1 PMID:16636475 -1.14.12.18 biphenyl ectopseudomonas oleovorans 0.168 0.114 3 PMID:16636475 -1.14.12.18 biphenyl pandoraea pnomenusa 4.1 4.1 1 PMID:17526697 -1.14.12.18 biphenyl paraburkholderia xenovorans 1.1 0.85 4 PMID:17526697;PMID:32709719 -1.14.12.18 biphenyl pseudomonas sp. 4.6 2.2 3 PMID:18424535 -1.14.12.18 ethylbenzene ectopseudomonas oleovorans 0.219 0.13435 2 PMID:16636475 -1.14.12.18 toluene ectopseudomonas oleovorans 0.115 0.115 1 PMID:16636475 -1.14.12.23 2-nitrotoluene acidovorax sp. 2.3 0.34 3 PMID:16000792;PMID:25344236 -1.14.12.23 3-nitrotoluene acidovorax sp. 0.27 0.21000000000000002 2 PMID:25344236 -1.14.12.23 naphthalene acidovorax sp. 2.4 2.4 1 PMID:16000792 -1.14.12.23 nitrobenzene acidovorax sp. 0.3 0.28500000000000003 2 PMID:25344236 -1.14.12.7 phthalate comamonas testosteroni 2.1 2.1 1 PMID:34800435 -1.14.12.7 terephthalate comamonas testosteroni 2.0 2.0 1 PMID:34800435 -1.14.13.1 3-chlorosalicylate pseudomonas reinekei 1.3 1.3 1 PMID:17172348 -1.14.13.1 3-methylsalicylate pseudomonas reinekei 2.2 2.2 1 PMID:17172348 -1.14.13.1 4-(3-benzothiazol-2-yl-4-cyano-2-oxo-2h-chromen-7-yloxymethyl)-2-hydroxy-benzoic acid pseudomonas sp. 0.00075 0.00075 1 PMID:20695438 -1.14.13.1 4-chlorosalicylate pseudomonas reinekei 2.9 2.9 1 PMID:17172348 -1.14.13.1 4-methylsalicylate pseudomonas reinekei 6.4 6.4 1 PMID:17172348 -1.14.13.1 5-chlorosalicylate pseudomonas reinekei 1.6 1.6 1 PMID:17172348 -1.14.13.1 5-methylsalicylate pseudomonas reinekei 7.8 7.8 1 PMID:17172348 -1.14.13.1 nadh pseudomonas reinekei 5.4 5.4 1 PMID:17172348 -1.14.13.1 salicylate pseudomonas reinekei 4.6 4.6 1 PMID:17172348 -1.14.13.1 salicylate solanum lycopersicum 0.0783 0.0783 1 PMID:33793924 -1.14.13.101 atropine zonocerus variegatus 0.37 0.37 1 PMID:22363737 -1.14.13.101 heliotrine zonocerus variegatus 0.12 0.12 1 PMID:22363737 -1.14.13.101 monocrotaline zonocerus variegatus 0.96 0.96 1 PMID:22363737 -1.14.13.101 phalaenopsine zonocerus variegatus 0.13 0.13 1 PMID:22363737 -1.14.13.101 senecionine zonocerus variegatus 0.99 0.99 1 PMID:22363737 -1.14.13.105 (1r,4s)-1-hydroxy-2-oxolimonene rhodococcus erythropolis 4.9 4.9 1 PMID:10769172 -1.14.13.105 (1r,4s)-menthone rhodococcus erythropolis 3.6 3.6 1 PMID:10769172 -1.14.13.105 (1s,4r)-1-hydroxy-2-oxolimonene rhodococcus erythropolis 3.9 3.9 1 PMID:10769172 -1.14.13.105 (1s,4r)-menthone rhodococcus erythropolis 6.0 6.0 1 PMID:10769172 -1.14.13.105 (4r)-dihydrocarvone rhodococcus erythropolis 3.9 3.9 1 PMID:10769172 -1.14.13.113 nadh klebsiella pneumoniae 42.0 42.0 1 PMID:23259842 -1.14.13.113 nadh xanthomonas campestris 0.19 0.19 1 PMID:23760935 -1.14.13.113 nadph xanthomonas campestris 1.14 1.14 1 PMID:23760935 -1.14.13.113 urate klebsiella pneumoniae 42.0 42.0 3 PMID:19260710;PMID:23259842 -1.14.13.113 urate xanthomonas campestris 1.06 1.06 1 PMID:23760935 -1.14.13.114 4-hydroxybenzoate bordetella bronchiseptica 0.074 0.074 1 PMID:30810301 -1.14.13.114 4-hydroxybenzoic acid bordetella bronchiseptica 0.074 0.074 1 PMID:30810301 -1.14.13.114 5-chloro-6-hydroxynicotinate bordetella bronchiseptica 2.18 2.18 2 PMID:30810301 -1.14.13.114 6-hydroxynicotinate bordetella bronchiseptica 5.1 5.0 3 PMID:27218267;PMID:30810301 -1.14.13.114 6-hydroxynicotinate pseudomonas putida 2.2 2.2 1 PMID:27218267 -1.14.13.114 nadh bordetella bronchiseptica 5.0 4.2 3 PMID:27218267;PMID:30810301 -1.14.13.114 nadh pseudomonas putida 2.2 2.2 1 PMID:27218267 -1.14.13.127 nadh escherichia coli 0.691 0.691 1 PMID:31811039 -1.14.13.127 nadph escherichia coli 0.736 0.736 1 PMID:31811039 -1.14.13.128 1,7-dimethylxanthine pseudomonas putida 0.27 0.27 1 PMID:20966097 -1.14.13.128 7-methylxanthine pseudomonas putida 1.58 0.87 2 PMID:20966097;PMID:23813729 -1.14.13.128 caffeine pseudomonas putida 3.17 3.17 1 * -1.14.13.131 dimethyl sulfide hyphomicrobium sulfonivorans 5.45 5.45 1 PMID:21216999 -1.14.13.148 dimethyl sulfide candidatus pelagibacter sp. htcc7211 0.075 0.075 1 PMID:34630359 -1.14.13.148 ethionamide homo sapiens 0.973 0.973 1 PMID:18930751 -1.14.13.148 ethionamide mus musculus 1.01 1.01 1 PMID:18930751 -1.14.13.148 methimazole candidatus pelagibacter sp. htcc7211 0.087 0.087 1 PMID:34630359 -1.14.13.148 n,n,n-trimethylamine candidatus pelagibacter sp. htcc7211 0.373 0.373 1 PMID:34630359 -1.14.13.148 n,n-dimethylamine candidatus pelagibacter sp. htcc7211 0.298 0.298 1 PMID:34630359 -1.14.13.148 nadph candidatus pelagibacter sp. htcc7211 0.075 0.075 1 PMID:34630359 -1.14.13.154 erythromycin d saccharopolyspora erythraea 1.8 1.8 1 PMID:7849045 -1.14.13.160 2-methylcyclohexanone pseudomonas putida 0.9 0.9 1 PMID:22267661 -1.14.13.160 2-n-hexylcyclopentanone pseudomonas putida 13.6 7.7 2 PMID:22267661 -1.14.13.160 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetic acid pseudomonas putida 0.13 0.13 1 PMID:22267661 -1.14.13.160 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-coa pseudomonas putida 4.8 4.8 1 PMID:22267661 -1.14.13.160 2-oxocyclopentyl acetic acid pseudomonas putida 0.11 0.11 1 PMID:22267661 -1.14.13.160 2-oxocyclopentyl ethyl acetate pseudomonas putida 6.9 6.9 1 PMID:22267661 -1.14.13.160 4-methylcyclohexanone pseudomonas putida 5.6 5.6 1 PMID:22267661 -1.14.13.163 4-(6-hydroxypyridin-3-yl)-4-oxobutanoate ochrobactrum sp. 21.6 21.6 1 PMID:25344232 -1.14.13.163 4-(6-hydroxypyridin-3-yl)-4-oxobutanoate pseudomonas putida 7.74 7.74 1 PMID:25172510 -1.14.13.163 4-(6-hydroxypyridin-3-yl)-4-oxobutanoate pseudomonas sp. zz-5 2.1 2.1 1 * -1.14.13.163 nadh ochrobactrum sp. 17.5 17.5 1 PMID:25344232 -1.14.13.163 nadh pseudomonas putida 5.49 3.745 2 PMID:21949128;PMID:25172510 -1.14.13.163 nadh pseudomonas sp. zz-5 1.3 1.3 1 * -1.14.13.168 nadph arabidopsis thaliana 0.31 0.31 1 PMID:23188833 -1.14.13.172 salicylate ralstonia sp. 1.86 1.25 2 PMID:31066545 -1.14.13.178 1-methylxanthine pseudomonas putida 0.27 0.27 1 PMID:22328667 -1.14.13.178 caffeine pseudomonas putida 3.17 3.17 1 PMID:22328667 -1.14.13.178 paraxanthine pseudomonas putida 2.17 2.17 1 PMID:22328667 -1.14.13.178 theophylline pseudomonas putida 1.38 1.38 1 PMID:22328667 -1.14.13.179 3-methylxanthine pseudomonas putida 0.53 0.53 1 PMID:22328667 -1.14.13.179 caffeine pseudomonas putida 0.0038 0.0038 1 PMID:22328667 -1.14.13.179 theobromine pseudomonas putida 0.77 0.77 1 PMID:22328667 -1.14.13.179 theophylline pseudomonas putida 0.0045 0.0045 1 PMID:22328667 -1.14.13.181 13-deoxycarminomycin streptomyces sp. 0.00026 0.00026 1 PMID:9864343 -1.14.13.181 13-deoxydaunorubicin streptomyces sp. 0.024 0.024 1 PMID:9864343 -1.14.13.181 13-dihydrodaunorubicin streptomyces sp. 0.63 0.63 1 PMID:9864343 -1.14.13.181 daunorubicin streptomyces sp. 0.00012 0.00012 1 PMID:9864343 -1.14.13.182 2-heptyl-4(1h)-quinolone pseudomonas aeruginosa 2.7 2.7 1 PMID:20662781 -1.14.13.182 2-heptylquinolin-4(1h)-one microbulbifer sp. hz11 0.21 0.21 1 PMID:33452035 -1.14.13.182 2-nonyl-4(1h)-quinolone pseudomonas aeruginosa 2.5 2.5 1 PMID:20662781 -1.14.13.182 2-pentyl-4(1h)-quinolone pseudomonas aeruginosa 3.0 3.0 1 PMID:20662781 -1.14.13.182 2-propyl-4(1h)-quinolone pseudomonas aeruginosa 2.3 2.3 1 PMID:20662781 -1.14.13.182 nadh microbulbifer sp. hz11 0.3 0.3 1 PMID:33452035 -1.14.13.182 nadh pseudomonas aeruginosa 3.2 3.2 1 PMID:20662781 -1.14.13.182 nadph pseudomonas aeruginosa 3.8 3.8 1 PMID:20662781 -1.14.13.182 o2 pseudomonas aeruginosa 1.2 1.2 1 PMID:20662781 -1.14.13.189 nadph streptomyces sahachiroi 0.013 0.013 1 PMID:20485749 -1.14.13.195 l-ornithine aspergillus fumigatus 0.62 0.605 2 PMID:26375201 -1.14.13.195 l-ornithine saccharopolyspora erythraea 0.327 0.327 1 PMID:21650455 -1.14.13.195 nadh aspergillus fumigatus 0.73 0.73 1 PMID:22465572 -1.14.13.195 nadph aspergillus fumigatus 0.6 0.6 3 PMID:22465572;PMID:24072704 -1.14.13.196 l-ornithine amycolatopsis alba 0.34 0.27 2 PMID:28974024 -1.14.13.196 l-ornithine aspergillus fumigatus 0.87 0.5 5 PMID:20614882;PMID:24072704 -1.14.13.196 nadh aspergillus fumigatus 1.36 1.18 3 PMID:20614882;PMID:22465572 -1.14.13.196 nadph aspergillus fumigatus 1.25 0.615 4 PMID:20614882;PMID:22465572;PMID:24072704 -1.14.13.2 3,4-dihydroxybenzoate pseudomonas aeruginosa 0.33 0.33 1 PMID:31639299 -1.14.13.2 4-hydroxybenzoate corynebacterium glutamicum 2.8 2.8 1 PMID:18071645 -1.14.13.2 4-hydroxybenzoate cupriavidus pinatubonensis 30.4 24.2 2 PMID:30631308 -1.14.13.2 4-hydroxybenzoate pseudomonas aeruginosa 14.12 8.25 4 PMID:1910043;PMID:28650068;PMID:31639299;PMID:34295569 -1.14.13.2 4-hydroxybenzoate pseudomonas fluorescens 63.0 45.0 3 PMID:18176933;PMID:4380381 -1.14.13.2 4-hydroxybenzoate pseudomonas sp. 7.4 7.4 1 PMID:8706756 -1.14.13.2 nadh pseudomonas sp. 16.9 11.6 3 PMID:8706756 -1.14.13.2 nadph corynebacterium glutamicum 7.8 7.8 1 PMID:18071645 -1.14.13.2 nadph cupriavidus pinatubonensis 37.0 37.0 1 PMID:30631308 -1.14.13.2 nadph pseudomonas fluorescens 63.0 54.0 2 PMID:18176933 -1.14.13.2 nadph pseudomonas sp. 13.3 8.6 3 PMID:8706756 -1.14.13.2 p-hydroxybenzoate pseudomonas aeruginosa 7.5 6.85 2 PMID:14769033 -1.14.13.20 2,4-dichlorophenol acinetobacter sp. 6.83 6.83 1 PMID:7075592 -1.14.13.210 4-nitrophenol burkholderia sp. 0.014 0.014 1 PMID:16751499 -1.14.13.212 1,3,7-trimethylurate pseudomonas sp. 7.48 7.48 1 PMID:22609920 -1.14.13.212 1,3-dimethylurate pseudomonas sp. 3.08 3.08 1 PMID:22609920 -1.14.13.212 1-methylurate pseudomonas sp. 0.485 0.485 1 PMID:22609920 -1.14.13.212 3,7-dimethylurate pseudomonas sp. 1.97 1.97 1 PMID:22609920 -1.14.13.215 nadh streptomyces nodosus 0.113 0.113 1 PMID:23890006 -1.14.13.215 nadph streptomyces nodosus 0.324 0.324 1 PMID:23890006 -1.14.13.215 protoasukamycin streptomyces nodosus 16.67 16.67 1 PMID:23890006 -1.14.13.22 2-butanone acinetobacter calcoaceticus 0.3 0.29000000000000004 2 PMID:27873437;PMID:27935281 -1.14.13.22 2-butanone thermocrispum municipale 0.4 0.4 1 PMID:27873437 -1.14.13.22 2-hydroxycyclobutanone ilyonectria destructans 4.5 4.5 1 PMID:22075635 -1.14.13.22 2-methylcyclohexyl boronic acid acinetobacter sp. 8.4 8.4 1 * -1.14.13.22 2-phenylcyclohexanone ilyonectria destructans 0.73 0.73 1 PMID:22075635 -1.14.13.22 acetophenone acinetobacter calcoaceticus 0.4 0.4 1 PMID:27873437 -1.14.13.22 acetophenone thermocrispum municipale 0.1 0.1 1 PMID:27873437 -1.14.13.22 bicyclo[3.2.0]hept-2-en-6-one acinetobacter calcoaceticus 4.0 4.0 1 PMID:27873437 -1.14.13.22 bicyclo[3.2.0]hept-2-en-6-one acinetobacter johnsonii 13.4 13.4 1 PMID:24649397 -1.14.13.22 bicyclo[3.2.0]hept-2-en-6-one thermocrispum municipale 2.0 2.0 1 PMID:27873437 -1.14.13.22 cis-hex-2-enyl phenyl selenide acinetobacter sp. 0.683 0.683 1 * -1.14.13.22 cyclobutanone acinetobacter calcoaceticus 4.0 4.0 1 PMID:27873437 -1.14.13.22 cyclobutanone ilyonectria destructans 6.8 6.8 1 PMID:22075635 -1.14.13.22 cyclobutanone thermocrispum municipale 2.0 2.0 1 PMID:27873437 -1.14.13.22 cycloheptanone ilyonectria destructans 4.3 4.3 1 PMID:22075635 -1.14.13.22 cyclohexanone acidovorax sp. chx100 1.5 1.16 3 PMID:33844297 -1.14.13.22 cyclohexanone acinetobacter calcoaceticus 6.0 6.0 1 PMID:27873437 -1.14.13.22 cyclohexanone acinetobacter johnsonii 38.5 26.35 2 PMID:24649397;PMID:26410456 -1.14.13.22 cyclohexanone acinetobacter sp. 30.3 12.9 3 PMID:30030997;PMID:7093214 -1.14.13.22 cyclohexanone ilyonectria destructans 9.8 9.8 1 PMID:22075635 -1.14.13.22 cyclohexanone rhodococcus sp. hi-31 9.2 9.2 1 PMID:31124128 -1.14.13.22 cyclohexanone thermocrispum municipale 2.0 2.0 1 PMID:27873437 -1.14.13.22 cyclooctanone ilyonectria destructans 0.68 0.68 1 PMID:22075635 -1.14.13.22 cyclopentanone acinetobacter calcoaceticus 1.0 1.0 1 PMID:27873437 -1.14.13.22 cyclopentanone ilyonectria destructans 5.9 5.9 1 PMID:22075635 -1.14.13.22 cyclopentanone thermocrispum municipale 2.0 2.0 1 PMID:27873437 -1.14.13.22 delta-thiovalerolactone acinetobacter sp. 0.24 0.24 1 * -1.14.13.22 epsilon-thiocaprolactone acinetobacter sp. 0.227 0.227 1 * -1.14.13.22 ethylene monothiocarbonate acinetobacter sp. 2.38 2.38 1 * -1.14.13.22 gamma-thiobutyrolactone acinetobacter sp. 0.683 0.683 1 * -1.14.13.22 nadph acidovorax sp. chx100 1.17 1.17 1 PMID:33844297 -1.14.13.22 nadph acinetobacter sp. 13.5 0.82 3 * -1.14.13.22 o2 acidovorax sp. chx100 1.31 1.21 2 PMID:33844297 -1.14.13.22 phenyl propargyl selenide acinetobacter sp. 9.75 9.75 1 * -1.14.13.22 phenylacetone acinetobacter calcoaceticus 1.0 1.0 1 PMID:27873437 -1.14.13.22 phenylacetone thermocrispum municipale 1.0 1.0 1 PMID:27873437 -1.14.13.22 pyrmetazole acinetobacter sp. 1.12 0.7350000000000001 2 * -1.14.13.22 thioanisole acinetobacter calcoaceticus 3.0 3.0 1 PMID:27873437 -1.14.13.22 thioanisole thermocrispum municipale 2.0 2.0 1 PMID:27873437 -1.14.13.22 trans-hex-2-enyl phenyl selenide acinetobacter sp. 0.917 0.917 1 * -1.14.13.223 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] streptosporangium sibiricum 1.48 1.48 1 PMID:21612226 -1.14.13.225 [f-actin]-l-methionine homo sapiens 0.0169 0.0031 5 PMID:31949908 -1.14.13.225 nadh homo sapiens 0.28 0.28 1 PMID:21864500 -1.14.13.225 nadph homo sapiens 4.0 2.9 7 PMID:21864500;PMID:26845023 -1.14.13.230 butane thauera butanivorans 0.48 0.3 2 PMID:19383682 -1.14.13.230 ethane thauera butanivorans 0.76 0.76 1 PMID:19383682 -1.14.13.230 methane thauera butanivorans 1.3 1.3 1 PMID:19383682 -1.14.13.230 pentane thauera butanivorans 0.34 0.039 3 PMID:19383682 -1.14.13.230 propane thauera butanivorans 0.98 0.765 2 PMID:19383682 -1.14.13.231 alpha-doxycycline bacteroides thetaiotaomicron 1.3 1.3 1 PMID:15452119 -1.14.13.231 anhydrotetracycline bacteroides fragilis 0.7 0.55 2 PMID:20831817 -1.14.13.231 chlorotetracycline bacteroides fragilis 0.3 0.3 1 PMID:20831817 -1.14.13.231 chlortetracycline bacteroides fragilis 0.3 0.3 1 PMID:15452119 -1.14.13.231 chlortetracycline bacteroides thetaiotaomicron 0.3 0.3 1 PMID:15452119 -1.14.13.231 demeclocycline bacteroides fragilis 0.2 0.2 1 PMID:15452119 -1.14.13.231 demeclocycline bacteroides thetaiotaomicron 0.2 0.2 1 PMID:15452119 -1.14.13.231 doxycycline bacteroides fragilis 0.63 0.615 2 PMID:15452119;PMID:20831817 -1.14.13.231 doxycycline bacteroides thetaiotaomicron 0.63 0.63 1 PMID:15452119 -1.14.13.231 minocycline bacteroides fragilis 0.12 0.12 1 PMID:15452119 -1.14.13.231 minocycline bacteroides thetaiotaomicron 0.12 0.12 1 PMID:15452119 -1.14.13.231 nadph bacteroides fragilis 1.11 1.11 1 PMID:15452119 -1.14.13.231 nadph bacteroides thetaiotaomicron 1.11 1.11 1 PMID:15452119 -1.14.13.231 oxytetracycline bacteroides fragilis 1.3 1.3 1 PMID:15452119 -1.14.13.231 tetracycline bacteroides fragilis 0.32 0.32 1 PMID:15452119 -1.14.13.231 tetracycline bacteroides thetaiotaomicron 0.32 0.32 1 PMID:15452119 -1.14.13.231 tigecycline bacteroides fragilis 0.36 0.36 1 PMID:16128584 -1.14.13.236 anisole ectopseudomonas mendocina 0.16 0.16 1 PMID:19290655 -1.14.13.236 benzene ectopseudomonas mendocina 0.1 0.1 1 PMID:19290655 -1.14.13.236 chlorobenzene ectopseudomonas mendocina 0.075 0.075 1 PMID:19290655 -1.14.13.236 nitrobenzene ectopseudomonas mendocina 0.013 0.013 1 PMID:19290655 -1.14.13.236 norcarane ectopseudomonas mendocina 0.49 0.49 1 PMID:15595825 -1.14.13.236 toluene ectopseudomonas mendocina 3.3 1.7999999999999998 4 PMID:10651645;PMID:15595825;PMID:15882052;PMID:19290655 -1.14.13.24 2,3-dihydroxybenzoate rhodococcus jostii 10.0 10.0 1 PMID:22207056 -1.14.13.24 2,5-dihydroxybenzoate rhodococcus jostii 7.0 7.0 1 PMID:22207056 -1.14.13.24 3,5-dihydroxybenzoate rhodococcus jostii 13.0 13.0 1 PMID:22207056 -1.14.13.24 3-hydroxybenzoate martelella sp. ad-3 5.7 5.7 1 PMID:30034371 -1.14.13.24 3-hydroxybenzoate rhodococcus jostii 35.0 6.49 5 PMID:22207056;PMID:23864660;PMID:24129570 -1.14.13.24 nadh martelella sp. ad-3 7.8 7.8 1 PMID:30034371 -1.14.13.242 3-hydroxy-2-methylpyridine-5-carboxylate mesorhizobium loti 11.8 11.8 1 PMID:17270714 -1.14.13.242 5-hydroxynicotinic acid mesorhizobium loti 1300.0 655.35 2 PMID:17270714;PMID:27568368 -1.14.13.244 phenol stutzerimonas stutzeri 0.286 0.286 1 PMID:15066815 -1.14.13.248 l-aspartate streptomyces cremeus 1.14 1.14 1 PMID:26689788 -1.14.13.248 nadph streptomyces cremeus 1.19 1.19 1 PMID:26689788 -1.14.13.25 cycloheptanecarboxylate paraburkholderia terrae 4.8 4.8 1 PMID:34965585 -1.14.13.25 cyclohexanecarboxylate paraburkholderia terrae 15.9 15.9 1 PMID:34965585 -1.14.13.25 cyclopentanecarboxylate paraburkholderia terrae 5.6 5.6 1 PMID:34965585 -1.14.13.25 furan methylosinus trichosporium 7.6 7.6 1 PMID:2280705 -1.14.13.25 heptanoate paraburkholderia terrae 1.5 1.5 1 PMID:34965585 -1.14.13.25 hexanoate paraburkholderia terrae 3.5 3.5 1 PMID:34965585 -1.14.13.25 methane methylosinus trichosporium 3.7 3.7 1 PMID:2280705 -1.14.13.25 propene methylosinus trichosporium 4.4 4.4 1 PMID:2280705 -1.14.13.25 propylene methylococcus capsulatus 0.23 0.23 1 PMID:15962961 -1.14.13.251 nadh chromohalobacter israelensis 0.9 0.9 1 PMID:29703733 -1.14.13.251 nadph chromohalobacter israelensis 0.35 0.35 1 PMID:29703733 -1.14.13.252 cadaverine acinetobacter baumannii 0.54 0.54 1 PMID:36314559 -1.14.13.252 cadaverine streptomyces sviceus 0.38 0.38 1 PMID:33784308 -1.14.13.252 nadh acinetobacter baumannii 0.3 0.3 1 PMID:36314559 -1.14.13.252 nadh streptomyces sviceus 0.38 0.38 1 PMID:33784308 -1.14.13.252 nadph acinetobacter baumannii 0.7 0.7 1 PMID:36314559 -1.14.13.252 nadph streptomyces sviceus 0.28 0.28 1 PMID:33784308 -1.14.13.252 putrescine acinetobacter baumannii 0.6 0.6 1 PMID:36314559 -1.14.13.252 putrescine gordonia rubripertincta 0.266 0.266 1 * -1.14.13.252 putrescine streptomyces sviceus 0.28 0.28 1 PMID:33784308 -1.14.13.29 4-nitrophenol oryctolagus cuniculus 0.127 0.127 1 PMID:3702859 -1.14.13.33 4-hydroxybenzoate cupriavidus pinatubonensis 7.6 6.65 4 PMID:30631308 -1.14.13.33 4-hydroxybenzoate rhodococcus opacus 16.8 11.25 4 PMID:30631308 -1.14.13.33 nadh cupriavidus pinatubonensis 9.4 9.4 1 PMID:30631308 -1.14.13.33 nadh rhodococcus opacus 15.3 15.3 1 PMID:30631308 -1.14.13.33 nadph rhodococcus opacus 15.0 15.0 1 PMID:30631308 -1.14.13.39 adriamycin homo sapiens 95.0 5.3 5 PMID:15196992 -1.14.13.39 l-arginine rattus norvegicus 1.08 1.08 1 PMID:1372827 -1.14.13.39 menadione homo sapiens 96.0 9.5 5 PMID:15196992 -1.14.13.39 mitomycin c homo sapiens 26.0 2.2 5 PMID:15196992 -1.14.13.39 nadph rattus norvegicus 2.57 2.45 2 PMID:18852262 -1.14.13.39 nitric oxide rattus norvegicus 1.23 1.075 2 PMID:18852262 -1.14.13.39 nitroblue tetrazolium rattus norvegicus 0.65 0.65 1 PMID:1372827 -1.14.13.4 3-(2-hydroxyphenyl)propanoate pseudomonas sp. 4.48 4.48 1 PMID:227848 -1.14.13.40 2-aminobenzoyl-coa pseudomonas sp. 70.8 70.8 1 PMID:2591379 -1.14.13.44 2,2'-dihydroxybiphenyl pseudomonas nitroreducens 9.4 9.2 2 PMID:9305879 -1.14.13.44 2-hydroxybiphenyl pseudomonas nitroreducens 15.6 11.9 7 PMID:10559214;PMID:11733527;PMID:12105208;PMID:26275805;PMID:29297973;PMID:9305879 -1.14.13.44 2-sec-butylphenol pseudomonas nitroreducens 15.8 14.5 3 PMID:11733527;PMID:9305879 -1.14.13.44 guaiacol pseudomonas nitroreducens 0.95 0.95 1 PMID:11733527 -1.14.13.44 indole pseudomonas nitroreducens 0.005 0.005 1 PMID:12105208 -1.14.13.44 nadh pseudomonas nitroreducens 16.2 9.8 3 PMID:26275805;PMID:9305879 -1.14.13.44 nadph pseudomonas nitroreducens 18.8 15.0 2 PMID:9305879 -1.14.13.44 o2 pseudomonas nitroreducens 16.2 16.2 1 PMID:9305879 -1.14.13.5 imidazoleacetate pseudomonas sp. 37.7 37.7 1 PMID:5772468 -1.14.13.50 2,3,5,6-tetrachlorophenol sphingobium chlorophenolicum 0.32 0.32 1 PMID:22482720 -1.14.13.50 2,6-dichlorophenol sphingobium chlorophenolicum 0.046 0.046 1 PMID:22482720 -1.14.13.50 3,4,5-trichlorophenol sphingobium chlorophenolicum 0.01 0.01 1 PMID:22482720 -1.14.13.50 3,5-dichlorophenol sphingobium chlorophenolicum 0.01 0.01 1 PMID:22482720 -1.14.13.50 pentachlorophenol bacillus tropicus 4.58 4.58 1 PMID:33547987 -1.14.13.50 pentachlorophenol sphingobium chlorophenolicum 9300.0 0.024 3 PMID:15262224;PMID:22482720;PMID:25238136 -1.14.13.54 phenylacetone rhodococcus rhodochrous 1.5 1.5 1 PMID:22605340 -1.14.13.59 fad escherichia coli 0.405 0.405 1 PMID:11904218 -1.14.13.59 l-lysine mycolicibacterium smegmatis 0.55 0.43 3 PMID:21870809;PMID:24769337 -1.14.13.59 nadh nocardia farcinica 2.5 1.895 2 PMID:25802330 -1.14.13.59 nadph nocardia farcinica 2.9 1.185 4 PMID:25802330;PMID:27503802 -1.14.13.6 orcinol pseudomonas putida 26.0 26.0 1 PMID:1126936 -1.14.13.63 3,4-dihydroxyphenylacetate flavobacterium sp. 15.6 15.6 1 PMID:1935954 -1.14.13.63 3-hydroxyphenylacetate flavobacterium sp. 22.4 22.4 1 PMID:1935954 -1.14.13.63 nadh flavobacterium sp. 36.0 36.0 1 PMID:1935954 -1.14.13.63 nadph flavobacterium sp. 35.8 35.8 1 PMID:1935954 -1.14.13.64 2,3,5,6-tetrafluoro-4-hydroxybenzoate candida parapsilosis 7.5 7.5 1 PMID:9352916 -1.14.13.64 2,4-dihydroxybenzoate candida parapsilosis 19.8 19.8 1 PMID:9352916 -1.14.13.64 2,5-difluoro-4-hydroxybenzoate candida parapsilosis 12.0 12.0 1 PMID:9352916 -1.14.13.64 2,6-difluoro-4-hydroxybenzoate candida parapsilosis 8.5 8.5 1 PMID:9352916 -1.14.13.64 2-chloro-4-hydroxybenzoate candida parapsilosis 9.6 9.6 1 PMID:9352916 -1.14.13.64 2-fluoro-4-hydroxybenzoate candida parapsilosis 14.0 14.0 1 PMID:9352916 -1.14.13.64 3,4-dihydroxybenzoate candida parapsilosis 16.8 16.8 1 PMID:9352916 -1.14.13.64 3,5-difluoro-4-hydroxybenzoate candida parapsilosis 6.5 6.5 1 PMID:9352916 -1.14.13.64 3-amino-4-hydroxybenzoate candida parapsilosis 8.3 8.3 1 PMID:9352916 -1.14.13.64 3-chloro-4-hydroxybenzoate candida parapsilosis 17.0 17.0 1 PMID:9352916 -1.14.13.64 3-fluoro-4-hydroxybenzoate candida parapsilosis 18.1 18.1 1 PMID:9352916 -1.14.13.64 4-hydroxy-3-methoxybenzoate candida parapsilosis 11.8 11.8 1 PMID:9352916 -1.14.13.64 4-hydroxy-3-nitrobenzoate candida parapsilosis 19.8 19.8 1 PMID:9352916 -1.14.13.64 4-hydroxybenzoate candida parapsilosis 10.0 0.136 3 PMID:28583673;PMID:33684360 -1.14.13.7 2-cresol stutzerimonas stutzeri 0.95 0.95 1 PMID:16085870 -1.14.13.7 2-xylene stutzerimonas stutzeri 0.125 0.125 1 PMID:16085870 -1.14.13.7 3-cresol stutzerimonas stutzeri 0.61 0.61 1 PMID:16085870 -1.14.13.7 4-cresol stutzerimonas stutzeri 0.77 0.77 1 PMID:16085870 -1.14.13.7 benzene stutzerimonas stutzeri 0.1 0.1 1 PMID:16085870 -1.14.13.7 nadh acinetobacter radioresistens 1980.0 1980.0 1 PMID:12752444 -1.14.13.7 nadph cutaneotrichosporon cutaneum 11.5 11.5 1 PMID:569150 -1.14.13.7 phenol acinetobacter radioresistens 1980.0 1980.0 1 PMID:12752444 -1.14.13.7 phenol cutaneotrichosporon cutaneum 12.0 12.0 1 PMID:7858421 -1.14.13.7 phenol stutzerimonas stutzeri 1.02 0.653 2 PMID:15066815;PMID:16085870 -1.14.13.7 toluene stutzerimonas stutzeri 0.15 0.15 1 PMID:16085870 -1.14.13.7 various phenolic substrates cutaneotrichosporon cutaneum 13.2 13.2 1 PMID:569150 -1.14.13.8 10-[(n,n-dimethylaminooctyl)-2-(trifluoromethyl)]phenothiazine homo sapiens 0.72 0.385 6 PMID:20810540 -1.14.13.8 benzydamine homo sapiens 0.15 0.075 3 PMID:28137602;PMID:33152328 -1.14.13.8 bicyclo[4.2.0]octan-7-one rhodococcus jostii 1.7 1.7 1 * -1.14.13.8 clomiphene homo sapiens 0.0017 0.00145 2 PMID:28137602;PMID:29959872 -1.14.13.8 cyclobutanone rhodococcus jostii 1.3 1.3 1 * -1.14.13.8 cysteamine corynebacterium glutamicum 1.83 1.83 1 PMID:25851950 -1.14.13.8 ethionamide homo sapiens 1.5 0.973 5 PMID:18930751 -1.14.13.8 ethionamide mus musculus 9.45 4.52 5 PMID:18930751 -1.14.13.8 ethylenethiourea homo sapiens 0.036 0.036 1 PMID:17050781 -1.14.13.8 gsk5182 homo sapiens 0.037 0.037 1 PMID:29959872 -1.14.13.8 indole methylophaga aminisulfidivorans 0.7 0.7 1 PMID:18443301 -1.14.13.8 indole methylophaga sp. 1.28 0.795 10 PMID:31817552 -1.14.13.8 methimazole homo sapiens 0.525 0.08349999999999999 4 PMID:17050781;PMID:18948378 -1.14.13.8 methimazole methylophaga aminisulfidivorans 1.0 1.0 1 PMID:18443301 -1.14.13.8 methimazole methylophaga sp. 2.7 2.7 1 PMID:23357278 -1.14.13.8 methyl p-tolyl sulfide homo sapiens 42.3 42.3 1 PMID:19420133 -1.14.13.8 methyl p-tolyl sulfide mus musculus 2.9 2.075 2 PMID:17942081 -1.14.13.8 n,n-dimethylaniline methylophaga aminisulfidivorans 1.8 1.8 1 PMID:18443301 -1.14.13.8 n-methyl-tamoxifen homo sapiens 0.33 0.21500000000000002 2 PMID:16684653 -1.14.13.8 nadh rhodococcus jostii 2.0 2.0 1 * -1.14.13.8 nadph homo sapiens 23.6 23.6 1 PMID:19420133 -1.14.13.8 nadph methylophaga aminisulfidivorans 0.06 0.06 1 PMID:18443301 -1.14.13.8 nadph methylophaga sp. 7.3 7.3 1 PMID:23357278 -1.14.13.8 nadph rhodococcus jostii 2.8 2.8 1 * -1.14.13.8 nicotine methylophaga aminisulfidivorans 3.0 3.0 1 PMID:18443301 -1.14.13.8 o2 methylophaga sp. 7.7 7.7 1 PMID:23357278 -1.14.13.8 selegiline homo sapiens 0.023 0.023 1 PMID:28137602 -1.14.13.8 sulindac homo sapiens 0.047 0.047 1 PMID:17050781 -1.14.13.8 sulindac sulfide homo sapiens 0.027 0.01815 2 PMID:33152328 -1.14.13.8 tamoxifen homo sapiens 3.18 0.1501 6 PMID:16684653;PMID:28137602;PMID:29959872;PMID:33152328 -1.14.13.8 thiacetazone homo sapiens 1.335 0.085 3 PMID:18948378 -1.14.13.8 thiacetazone mycobacterium tuberculosis 0.085 0.0665 2 PMID:16544950 -1.14.13.8 thiourea corynebacterium glutamicum 0.67 0.67 1 PMID:25851950 -1.14.13.8 tozasertib homo sapiens 0.155 0.155 1 PMID:28137602 -1.14.13.8 trimethylamine corynebacterium glutamicum 2.6 2.6 1 PMID:25851950 -1.14.13.8 trimethylamine homo sapiens 0.034 0.034 1 PMID:17050781 -1.14.13.8 trimethylamine methylophaga aminisulfidivorans 6.1 6.1 1 PMID:18443301 -1.14.13.8 trimethylamine methylophaga sp. 6.1 6.1 1 PMID:23357278 -1.14.13.81 magnesium-protoporphyrin ix 13-monomethyl ester rubrivivax gelatinosus 0.0177 0.0164 2 PMID:33731920 -1.14.13.84 2'-hydroxyacetophenone pseudomonas putida 21.2 21.2 1 PMID:19251889 -1.14.13.84 2,4-pentanedione pseudomonas fluorescens 2.1 2.1 1 PMID:12514023 -1.14.13.84 2,4-pentanedione pseudomonas putida 3.5 3.5 1 PMID:19251889 -1.14.13.84 2-acetylpyridine pseudomonas fluorescens 7.8 7.8 1 PMID:12514023 -1.14.13.84 2-acetylpyrrole pseudomonas fluorescens 9.4 9.4 1 PMID:12514023 -1.14.13.84 2-acetylpyrrole pseudomonas putida 11.3 11.3 1 PMID:19251889 -1.14.13.84 2-decanone pseudomonas putida 4.2 4.2 1 PMID:19251889 -1.14.13.84 2-hydroxyacetophenone pseudomonas fluorescens 6.7 6.7 1 PMID:12514023 -1.14.13.84 2-phenylpropionaldehyde pseudomonas putida 8.7 8.7 1 PMID:19251889 -1.14.13.84 2-pyrrole carboxaldehyde pseudomonas fluorescens 8.6 8.6 1 PMID:12514023 -1.14.13.84 3'-hydroxyacetophenone pseudomonas putida 8.1 8.1 1 PMID:19251889 -1.14.13.84 3-aminoacetophenone pseudomonas putida 1.0 1.0 1 PMID:19251889 -1.14.13.84 3-chloro-2-butanone pseudomonas fluorescens 7.4 7.4 1 PMID:12514023 -1.14.13.84 3-hydroxyacetophenone pseudomonas fluorescens 4.8 4.8 1 PMID:12514023 -1.14.13.84 3-methoxyacetophenone pseudomonas putida 0.4 0.4 1 PMID:19251889 -1.14.13.84 3-nitroacetophenone pseudomonas putida 1.2 1.2 1 PMID:19251889 -1.14.13.84 4-acetylpyridine pseudomonas fluorescens 0.5 0.5 1 PMID:12514023 -1.14.13.84 4-aminoacetophenone pseudomonas fluorescens 12.7 12.5 2 PMID:11322873;PMID:12514023 -1.14.13.84 4-aminoacetophenone pseudomonas putida 8.2 8.2 1 PMID:19251889 -1.14.13.84 4-chloroacetophenone pseudomonas putida 1.6 1.6 1 PMID:19251889 -1.14.13.84 4-fluoroacetophenone pseudomonas fluorescens 0.6 0.6 2 PMID:11322873;PMID:12514023 -1.14.13.84 4-fluoroacetophenone pseudomonas putida 1.3 1.3 1 PMID:19251889 -1.14.13.84 4-hydroxy-3-methylacetophenone pseudomonas fluorescens 5.4 5.4 1 PMID:11322873 -1.14.13.84 4-hydroxyacetophenone pseudomonas fluorescens 12.6 11.35 2 PMID:11322873;PMID:12514023 -1.14.13.84 4-hydroxyacetophenone pseudomonas putida 9.8 9.8 1 PMID:19251889 -1.14.13.84 4-hydroxybenzaldehyde pseudomonas fluorescens 7.6 7.6 2 PMID:11322873;PMID:12514023 -1.14.13.84 4-hydroxypropiophenone pseudomonas fluorescens 11.9 11.25 2 PMID:11322873;PMID:12514023 -1.14.13.84 4-methoxyacetophenone pseudomonas fluorescens 1.7 1.7 2 PMID:11322873;PMID:12514023 -1.14.13.84 4-methoxyacetophenone pseudomonas putida 1.2 1.2 1 PMID:19251889 -1.14.13.84 4-methylacetophenone pseudomonas fluorescens 6.3 6.3 2 PMID:11322873;PMID:12514023 -1.14.13.84 4-methylacetophenone pseudomonas putida 4.4 4.4 1 PMID:19251889 -1.14.13.84 4-nitroacetophenone pseudomonas putida 2.6 2.6 1 PMID:19251889 -1.14.13.84 acetophenone pseudomonas fluorescens 13.2 8.85 2 PMID:11322873;PMID:12514023 -1.14.13.84 acetophenone pseudomonas putida 16.3 16.3 1 PMID:19251889 -1.14.13.84 acetylcyclohexane pseudomonas fluorescens 3.9 3.9 1 PMID:12514023 -1.14.13.84 benzaldehyde pseudomonas fluorescens 2.2 2.2 1 PMID:12514023 -1.14.13.84 benzaldehyde pseudomonas putida 2.2 2.2 1 PMID:19251889 -1.14.13.84 bicyclohept-2-en-6-one pseudomonas fluorescens 6.7 6.7 1 PMID:12514023 -1.14.13.84 butyrophenone pseudomonas fluorescens 1.2 1.2 1 PMID:12514023 -1.14.13.84 butyrophenone pseudomonas putida 4.9 4.9 1 PMID:19251889 -1.14.13.84 cyclohexane carboxaldehyde pseudomonas fluorescens 5.0 5.0 1 PMID:12514023 -1.14.13.84 hydroxyacetone pseudomonas fluorescens 4.1 4.1 1 PMID:12514023 -1.14.13.84 isobutyrophenone pseudomonas fluorescens 2.5 2.5 1 PMID:12514023 -1.14.13.84 methyl 4-tolyl sulfide pseudomonas fluorescens 7.3 7.3 1 PMID:12514023 -1.14.13.84 methyl-4-tolyl sulfide pseudomonas putida 20.0 20.0 1 PMID:19251889 -1.14.13.84 methylphenyl sulfide pseudomonas fluorescens 4.7 4.7 1 PMID:12514023 -1.14.13.84 nadh pseudomonas fluorescens 1.7 1.7 1 PMID:15153101 -1.14.13.84 nadph pseudomonas fluorescens 10.1 9.7 2 PMID:11322873;PMID:15153101 -1.14.13.84 propiophenone pseudomonas fluorescens 11.0 11.0 1 PMID:12514023 -1.14.13.84 propiophenone pseudomonas putida 2.6 2.6 1 PMID:19251889 -1.14.13.84 trifluoroacetophenone pseudomonas putida 15.4 15.4 1 PMID:19251889 -1.14.13.9 5-bromo-l-kynurenine cytophaga hutchinsonii 0.6 0.6 1 PMID:28302400 -1.14.13.9 5-chloro-l-kynurenine cytophaga hutchinsonii 0.8 0.8 1 PMID:28302400 -1.14.13.9 kynurenine pseudomonas fluorescens 4.9 3.1 2 PMID:16973376 -1.14.13.9 l-kynurenine aedes aegypti 1.88 1.88 1 PMID:12974953 -1.14.13.9 l-kynurenine cytophaga hutchinsonii 2.0 2.0 1 PMID:28302400 -1.14.13.9 nadh aedes aegypti 0.85 0.85 1 PMID:12974953 -1.14.13.9 nadph aedes aegypti 2.03 2.03 1 PMID:12974953 -1.14.13.92 (2-methylphenyl)acetone thermobifida fusca 2.0 2.0 1 PMID:15599520 -1.14.13.92 2-dodecanone mycobacterium tuberculosis 0.023 0.023 1 PMID:14610090 -1.14.13.92 2-dodecanone thermobifida fusca 0.23 0.23 1 PMID:15599520 -1.14.13.92 2-octanone thermobifida fusca 1.0 0.61 2 PMID:24247989;PMID:29318252 -1.14.13.92 2-phenylcyclohexanone thermobifida fusca 0.07 0.07 2 PMID:24247989;PMID:29318252 -1.14.13.92 4-hydroxyacetophenone thermobifida fusca 0.34 0.34 1 PMID:15599520 -1.14.13.92 benzylacetone mycobacterium tuberculosis 0.021 0.021 1 PMID:14610090 -1.14.13.92 benzylacetone thermobifida fusca 1.8 1.8 1 PMID:15599520 -1.14.13.92 bicyclohept-2-en-6-one thermobifida fusca 1.1 1.1 1 PMID:15599520 -1.14.13.92 cyclopentanone thermobifida fusca 0.9 0.9 2 PMID:24247989;PMID:29318252 -1.14.13.92 ethionamide mycobacterium tuberculosis 0.027 0.027 1 PMID:14610090 -1.14.13.92 methyl 4-tolylsulfide thermobifida fusca 2.1 2.1 1 PMID:15599520 -1.14.13.92 nadph thermobifida fusca 3.1 3.1 1 PMID:20703875 -1.14.13.92 phenylacetone mycobacterium tuberculosis 0.26 0.1385 2 PMID:14610090 -1.14.13.92 phenylacetone thermobifida fusca 3.0 2.15 4 PMID:15599520;PMID:24247989;PMID:29318252 -1.14.14.1 12-methyl-tetradecanoic acid bacillus licheniformis 13.9 13.9 1 PMID:18483737 -1.14.14.1 13-methyl-tetradecanoic acid bacillus licheniformis 21.1 21.1 1 PMID:18483737 -1.14.14.1 avermectin streptomyces tubercidicus 0.048 0.048 1 PMID:16269732 -1.14.14.1 cytochrome c bacillus licheniformis 122.4 122.4 1 PMID:18483737 -1.14.14.1 dodecanoic acid bacillus licheniformis 27.7 27.7 1 PMID:18483737 -1.14.14.1 hexadecanoic acid bacillus licheniformis 25.65 25.65 1 PMID:18483737 -1.14.14.1 linoleic acid bacillus licheniformis 29.3 29.3 1 PMID:18483737 -1.14.14.1 nadh rhodococcus ruber 6.0 6.0 1 PMID:16607529 -1.14.14.1 nadph priestia megaterium 0.45 0.45 1 PMID:16716428 -1.14.14.1 nadph rhodococcus ruber 12.75 12.75 1 PMID:16607529 -1.14.14.1 omega-(p-nitrophenyl)decanoic acid bacillus subtilis 1.5 1.5 1 PMID:14741768 -1.14.14.1 omega-(p-nitrophenyl)dodecanoic acid bacillus subtilis 3.1 3.1 1 PMID:14741768 -1.14.14.1 omega-(p-nitrophenyl)octanoic acid bacillus subtilis 0.4 0.4 1 PMID:14741768 -1.14.14.1 palmitoleic acid bacillus licheniformis 22.8 22.8 1 PMID:18483737 -1.14.14.1 stearic acid bacillus licheniformis 16.18 16.18 1 PMID:18483737 -1.14.14.1 tetradecanoic acid bacillus licheniformis 59.8 59.8 1 PMID:18483737 -1.14.14.108 fad pseudomonas putida 650.0 650.0 1 PMID:4286778 -1.14.14.108 nadh pseudomonas putida 317.0 42.5 4 PMID:4286778;PMID:4310834 -1.14.14.11 styrene herbaspirillum huttiense 0.036 0.036 1 PMID:35230494 -1.14.14.11 styrene pseudomonas putida 1.08 1.08 1 PMID:30678678 -1.14.14.11 styrene pseudomonas sp. 1.6 1.6 1 PMID:15292130 -1.14.14.111 syn-pimara-7,15-diene oryza sativa 46.0 46.0 1 PMID:21175892 -1.14.14.111 syn-stemod-13(17)-ene oryza sativa 49.0 49.0 1 PMID:21175892 -1.14.14.114 artemisinic aldehyde artemisia annua 1.53 1.53 1 * -1.14.14.114 dihydroartemisinic aldehyde artemisia annua 7.74 7.74 1 * -1.14.14.12 3,17-dihydroxy-9,10-seconandrost-1,3,5(10)-triene-9-one mycobacterium tuberculosis 0.24 0.24 1 PMID:20448045 -1.14.14.12 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione mycobacterium tuberculosis 0.2 0.1375 2 PMID:20448045 -1.14.14.12 3-hydroxybiphenyl mycobacterium tuberculosis 0.11 0.11 1 PMID:20448045 -1.14.14.12 o2 mycobacterium tuberculosis 0.031 0.031 1 PMID:20448045 -1.14.14.123 ent-cassadiene oryza sativa 0.006 0.006 1 PMID:22215681 -1.14.14.123 ent-isokaurene oryza sativa 0.015 0.015 1 PMID:22215681 -1.14.14.123 ent-kaurene oryza sativa 0.009 0.009 1 PMID:22215681 -1.14.14.123 ent-pimaradiene oryza sativa 0.009 0.009 1 PMID:22215681 -1.14.14.123 ent-sandaracopimaradien-3beta-ol oryza sativa 0.011 0.011 1 PMID:22215681 -1.14.14.123 syn-pimaradiene oryza sativa 0.006 0.006 1 PMID:22215681 -1.14.14.127 methyl (2e,6e)-farnesoate diploptera punctata 0.005 0.005 1 PMID:15024118 -1.14.14.14 androst-4-ene-3,17-dione aptenodytes forsteri 0.02 0.02 1 PMID:29684698 -1.14.14.141 (+)-marmesin ammi majus 340.0 340.0 1 PMID:17068340 -1.14.14.147 (22s)-22-hydroxycampest-4-en-3-one arabidopsis thaliana 0.023 0.02 2 PMID:17138693 -1.14.14.147 (22s)-22-hydroxycampesterol arabidopsis thaliana 0.002 0.0019 2 PMID:17138693 -1.14.14.147 (22s,24r)-22-hydroxy-5alpha-ergostan-3-one arabidopsis thaliana 0.046 0.0335 2 PMID:17138693 -1.14.14.147 3-epi-6-deoxocathasterone arabidopsis thaliana 0.05 0.034 2 PMID:17138693 -1.14.14.147 6-deoxocathasterone arabidopsis thaliana 0.0048 0.0035499999999999998 2 PMID:17138693 -1.14.14.148 (+)-columbianetin pastinaca sativa 1.9 1.1099999999999999 2 PMID:19098286 -1.14.14.148 syn-[3'd]columbianetin pastinaca sativa 3.9 0.27 3 PMID:19098286 -1.14.14.149 1beta-hydroxy-5-epiaristolochene nicotiana tabacum 0.582 0.582 1 PMID:15522862 -1.14.14.149 5-epiaristolochene nicotiana tabacum 0.493 0.493 1 PMID:15522862 -1.14.14.15 s-((3s)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl)-[peptidyl-carrier protein sgcc2] streptomyces globisporus 0.023 0.023 1 PMID:18426211 -1.14.14.151 (-)-vetispiradiene hyoscyamus muticus 2.1 2.1 1 PMID:17715131 -1.14.14.151 5-epiaristolochene hyoscyamus muticus 0.2 0.2 1 PMID:17715131 -1.14.14.151 valencene hyoscyamus muticus 1.9 1.9 1 PMID:17715131 -1.14.14.154 4alpha,14alpha-dimethyl-5alpha-ergosta-8,24(28)-dien-3beta-ol naegleria fowleri 0.433 0.433 1 PMID:34842434 -1.14.14.154 eburicol malassezia globosa 0.09 0.09 1 PMID:27291783 -1.14.14.154 lanosterol candida albicans 0.55 0.55 1 PMID:28258218 -1.14.14.154 lanosterol malassezia globosa 0.03 0.03 1 PMID:27291783 -1.14.14.154 lanosterol naegleria fowleri 1.067 1.067 1 PMID:34842434 -1.14.14.154 obtusifoliol malassezia globosa 0.06 0.06 1 PMID:27291783 -1.14.14.16 17a-hydroxyprogesterone bos taurus 0.322 0.322 1 PMID:6767716 -1.14.14.16 17alpha-hydroxyprogesterone bos taurus 0.67 0.67 1 PMID:25855791 -1.14.14.16 17alpha-hydroxyprogesterone homo sapiens 4.0 4.0 2 PMID:25855791;PMID:26172259;PMID:28539365 -1.14.14.16 progesterone bos taurus 0.172 0.125 2 PMID:25855791;PMID:6767716 -1.14.14.16 progesterone homo sapiens 2.8 2.8 2 PMID:25855791;PMID:26172259;PMID:28539365 -1.14.14.17 (3s)-squalene-2,3-epoxide rattus norvegicus 0.0075 0.0075 1 PMID:17112472 -1.14.14.17 squalene homo sapiens 0.0183 0.0183 1 PMID:10666321 -1.14.14.17 squalene rattus norvegicus 0.076 0.0683 3 PMID:10679280;PMID:17112472;PMID:3927114;PMID:6817796 -1.14.14.175 abieta-8,11,13-triene salvia miltiorrhiza 4.4 4.4 1 PMID:23812755 -1.14.14.178 campestanol arabidopsis thaliana 0.00082 0.00082 1 PMID:16460510 -1.14.14.178 campesterol arabidopsis thaliana 0.03 0.03 1 PMID:16460510 -1.14.14.18 heme bos taurus 0.0583 0.0583 1 PMID:6806282 -1.14.14.18 heme gallus gallus 0.32 0.32 1 PMID:2158889 -1.14.14.183 taxusin taxus cuspidata 0.05 0.05 1 PMID:15178487 -1.14.14.19 17alpha-hydroxypregnenolone homo sapiens 0.00283 0.00283 1 PMID:8396144 -1.14.14.19 pregnenolone danio rerio 0.85 0.44 2 PMID:25533464 -1.14.14.19 pregnenolone homo sapiens 0.11 0.0065 3 PMID:25301938;PMID:28684414 -1.14.14.19 progesterone bos taurus 1.55 1.55 1 PMID:2180429 -1.14.14.19 progesterone danio rerio 1.6 0.8500000000000001 2 PMID:25533464 -1.14.14.19 progesterone homo sapiens 0.17 0.03665 6 PMID:25301938;PMID:28684414;PMID:8396144 -1.14.14.19 progesterone sus scrofa 0.258 0.258 1 PMID:8240357 -1.14.14.197 progesterone priestia megaterium 0.3 0.3 1 PMID:22532270 -1.14.14.20 fad parageobacillus thermoglucosidasius 43.0 43.0 1 PMID:12968028 -1.14.14.20 fmn parageobacillus thermoglucosidasius 180.0 180.0 1 PMID:12968028 -1.14.14.20 riboflavin parageobacillus thermoglucosidasius 147.0 147.0 1 PMID:12968028 -1.14.14.21 dibenzothiophene rhodococcus erythropolis 0.0473 0.0473 1 PMID:31132321;PMID:32303871 -1.14.14.23 25-hydroxycholesterol homo sapiens 0.015 0.015 1 PMID:24927729 -1.14.14.23 27-hydroxycholesterol homo sapiens 0.0685 0.0685 1 PMID:24927729 -1.14.14.23 7-dehydrocholesterol homo sapiens 0.04 0.04 1 PMID:21813643 -1.14.14.23 cholest-4-en-3-one homo sapiens 0.003 0.003 1 PMID:24927729 -1.14.14.23 cholesterol homo sapiens 0.008 0.008 1 PMID:24927729 -1.14.14.23 cholesterol rattus norvegicus 0.833 0.0778 3 PMID:2154492;PMID:3584134 -1.14.14.23 lathosterol homo sapiens 0.12 0.09 2 PMID:21813643 -1.14.14.24 1alpha-hydroxycholecalciferol rattus norvegicus 0.063 0.063 1 PMID:2844763 -1.14.14.24 1alpha-hydroxyvitamin d2 homo sapiens 0.02 0.02 1 PMID:18511070 -1.14.14.24 1alpha-hydroxyvitamin d3 homo sapiens 0.037 0.02225 2 PMID:16842832;PMID:18511070 -1.14.14.24 1alpha-hydroxyvitamin d3 rattus norvegicus 22.0 11.1835 2 PMID:15026419;PMID:16842832 -1.14.14.24 vitamin d2 homo sapiens 0.017 0.009850000000000001 2 PMID:15465040;PMID:16842832 -1.14.14.24 vitamin d2 rattus norvegicus 0.014 0.014 1 PMID:16842832 -1.14.14.24 vitamin d3 homo sapiens 0.008 0.0042 3 PMID:16842832;PMID:18511070;PMID:28716760 -1.14.14.24 vitamin d3 rattus norvegicus 3.3 1.6584999999999999 2 PMID:15026419;PMID:16842832 -1.14.14.25 (24s)-24-hydroxycholesterol homo sapiens 0.0153 0.008235 2 PMID:15234274;PMID:18621681 -1.14.14.25 cholesterol homo sapiens 0.11 0.0559 2 PMID:16434543;PMID:18621681 -1.14.14.25 cholesterol 3-sulfate homo sapiens 0.0076 0.0076 1 PMID:18621681 -1.14.14.28 hexadecane geobacillus thermodenitrificans 0.02 0.02 1 PMID:22526792 -1.14.14.29 5alpha-androstane-3beta,17beta-diol sus scrofa 0.0166 0.0166 1 PMID:18331353 -1.14.14.29 dehydroepiandrosterone sus scrofa 0.033 0.033 1 PMID:18331353 -1.14.14.3 fmnh photorhabdus luminescens 3.17e-05 2.5e-05 3 PMID:8120017 -1.14.14.3 fmnh2 vibrio harveyi 0.1 0.1 1 PMID:16949542 -1.14.14.30 2-methylpropan-1-amine streptomyces viridifaciens 1.97 1.97 1 PMID:33350810 -1.14.14.32 17alpha-hydroxypregnenolone homo sapiens 128.0 0.03755 4 PMID:20197673;PMID:28684414;PMID:35287432 -1.14.14.32 17alpha-hydroxyprogesterone homo sapiens 0.0033 0.0019 3 PMID:28684414;PMID:35287432 -1.14.14.32 pregnenolone homo sapiens 0.11 0.045 3 PMID:28684414 -1.14.14.32 progesterone homo sapiens 0.17 0.055499999999999994 4 PMID:28684414 -1.14.14.33 ethylenediaminetetraacetate edta-degrading bacterium bnc1 47.1 13.2 5 PMID:26928990;PMID:9683478 -1.14.14.36 l-tyrosine sorghum bicolor 5.83 3.58 6 PMID:7574710;PMID:7876084 -1.14.14.38 l-isoleucine manihot esculenta 0.103 0.103 1 PMID:10636899 -1.14.14.38 l-valine lotus japonicus 1.23 1.03 2 PMID:15122013 -1.14.14.38 l-valine manihot esculenta 0.162 0.161 2 PMID:10636899 -1.14.14.39 l-isoleucine lotus japonicus 3.67 2.835 4 PMID:15122013 -1.14.14.39 l-isoleucine manihot esculenta 0.1 0.1 1 PMID:10636899 -1.14.14.39 l-valine lotus japonicus 0.83 0.78 2 PMID:15122013 -1.14.14.41 (e)-2-methylbutanal oxime manihot esculenta 0.28 0.28 1 PMID:21045121 -1.14.14.41 (e)-2-methylpropanal oxime manihot esculenta 0.35 0.35 1 PMID:21045121 -1.14.14.41 n-hydroxy-2-(4-hydroxypheny)-lethanimine manihot esculenta 0.13 0.13 1 PMID:21045121 -1.14.14.41 n-hydroxy-2-phenylethanimine manihot esculenta 0.02 0.02 1 PMID:21045121 -1.14.14.43 (e)-4-hydroxyphenylacetaldoxime arabidopsis thaliana 0.43 0.43 1 PMID:12970475 -1.14.14.43 (e)-phenylacetaldoxime arabidopsis thaliana 0.42 0.42 1 PMID:12970475 -1.14.14.43 indole-3-acetaldoxime arabidopsis thaliana 2.33 2.33 1 PMID:12970475 -1.14.14.44 (e)-phenylacetaldehyde oxime prunus mume 0.77 0.77 1 PMID:25015725 -1.14.14.44 4-hydroxyphenylacetaldoxime prunus mume 0.62 0.62 1 PMID:25015725 -1.14.14.44 4-hydroxyphenylacetonitrile prunus mume 0.57 0.57 1 PMID:25015725 -1.14.14.44 indole-3-acetaldoxime prunus mume 0.028 0.028 1 PMID:25015725 -1.14.14.44 indole-3-acetonitrile prunus mume 0.1 0.1 1 PMID:25015725 -1.14.14.44 phenylacetonitrile prunus mume 0.4 0.4 1 PMID:25015725 -1.14.14.45 (e)-indol-3-ylacetaldehyde oxime arabidopsis thaliana 0.87 0.65 2 PMID:11553739;PMID:12970475 -1.14.14.45 (e)-p-hydroxyphenylacetaldehyde oxime arabidopsis thaliana 0.23 0.195 2 PMID:11553739;PMID:12970475 -1.14.14.45 (e)-phenylacetaldehyde oxime arabidopsis thaliana 0.78 0.515 2 PMID:11553739;PMID:12970475 -1.14.14.45 indole-3-acetaldoxime arabidopsis thaliana 0.88 0.88 1 PMID:11158532 -1.14.14.45 p-hydroxyphenylacetaldoxime arabidopsis thaliana 0.27 0.27 1 PMID:11333274 -1.14.14.47 tetrahydrobiopterin bacillus subtilis 0.183 0.183 1 PMID:11856757 -1.14.14.5 octanesulfonate escherichia coli 0.88 0.85 4 PMID:19770075;PMID:24798142;PMID:26634408;PMID:32881481 -1.14.14.55 quinine homo sapiens 0.125 0.064135 2 PMID:8968357 -1.14.14.58 (3s)-(e)-nerolidol arabidopsis thaliana 0.2 0.2 1 PMID:21088219 -1.14.14.58 (3s)-(e,e)-geranyllinalool arabidopsis thaliana 0.11 0.11 1 PMID:21088219 -1.14.14.58 (3s,6e)-nerolidol arabidopsis thaliana 0.2 0.2 1 PMID:21088219 -1.14.14.58 (e,e)-geranyllinalool arabidopsis thaliana 0.11 0.11 1 PMID:21088219 -1.14.14.59 (3s,6e)-nerolidol arabidopsis thaliana 0.2 0.2 1 PMID:21088219 -1.14.14.66 demethylsuberosin ficus carica 0.37 0.37 1 PMID:33978969 -1.14.14.68 9beta-pimara-7,15-diene oryza sativa 1.4 1.4 1 PMID:25758958 -1.14.14.69 ent-cassa-12,15-diene oryza sativa japonica group 0.11 0.11 1 PMID:21985968 -1.14.14.70 ent-cassadiene oryza sativa 0.017 0.017 1 PMID:22247270 -1.14.14.70 ent-kaurene oryza sativa 0.022 0.022 1 PMID:22247270 -1.14.14.70 ent-sandaracopimaradiene oryza sativa 0.013 0.013 1 PMID:22247270 -1.14.14.76 ent-isokaurene oryza sativa 0.01 0.01 1 PMID:21985968 -1.14.14.77 2-methyl phenylacetonitrile chamberlinius hualienensis 1.12 1.12 1 PMID:28286729 -1.14.14.77 3-methyl phenylacetonitrile chamberlinius hualienensis 1.09 1.09 1 PMID:28286729 -1.14.14.77 4-hydroxyphenylacetonitrile chamberlinius hualienensis 0.71 0.71 1 PMID:28286729 -1.14.14.77 phenylacetonitrile chamberlinius hualienensis 3.07 3.07 1 PMID:28286729 -1.14.14.78 3-hydroxypalmitate homo sapiens 0.458 0.458 1 PMID:19932081 -1.14.14.78 arachidonic acid homo sapiens 0.009 0.009 1 PMID:19932081 -1.14.14.78 oleic acid homo sapiens 0.02 0.02 1 PMID:19932081 -1.14.14.78 palmitic acid homo sapiens 0.03 0.03 1 PMID:19932081 -1.14.14.80 arachidonic acid homo sapiens 0.01 0.01 1 PMID:10620324 -1.14.14.80 arachidonic acid rattus norvegicus 0.1 0.03 4 PMID:10620324 -1.14.14.80 lauric acid homo sapiens 0.7 0.258 3 PMID:10620324;PMID:27793475 -1.14.14.80 lauric acid rattus norvegicus 10.8 2.51 4 PMID:10620324 -1.14.14.80 myristic acid homo sapiens 0.83 0.193 3 PMID:10620324;PMID:27793475 -1.14.14.80 myristic acid rattus norvegicus 3.8 0.9199999999999999 4 PMID:10620324 -1.14.14.80 oleic acid homo sapiens 0.01 0.01 1 PMID:10620324 -1.14.14.80 oleic acid rattus norvegicus 0.02 0.015 4 PMID:10620324 -1.14.14.80 palmitic acid arabidopsis thaliana 0.002 0.002 1 PMID:9500987 -1.14.14.80 palmitic acid homo sapiens 0.17 0.068 3 PMID:10620324;PMID:27793475 -1.14.14.80 palmitic acid rattus norvegicus 1.0 0.1 3 PMID:10620324 -1.14.14.81 apigenin billardiera heterophylla 13.4 13.4 1 PMID:25269395 -1.14.14.81 dihydrokaempferol billardiera heterophylla 81.4 81.4 1 PMID:25269395 -1.14.14.81 kaempferol billardiera heterophylla 17.0 17.0 1 PMID:25269395 -1.14.14.81 naringenin billardiera heterophylla 10.6 10.6 1 PMID:25269395 -1.14.14.82 5-deoxyleucopelargonidin arabidopsis thaliana 12.3 12.3 1 PMID:25269395 -1.14.14.82 5-deoxyleucopelargonidin tagetes erecta 38.7 38.7 1 PMID:25269395 -1.14.14.82 apigenin arabidopsis thaliana 9.3 9.3 1 PMID:25269395 -1.14.14.82 apigenin fragaria x ananassa 13.4 13.4 1 PMID:25269395 -1.14.14.82 apigenin tagetes erecta 22.1 22.1 1 PMID:25269395 -1.14.14.82 dihydrokaempferol arabidopsis thaliana 12.7 12.7 1 PMID:25269395 -1.14.14.82 dihydrokaempferol camellia sinensis 1.6e-07 1.6e-07 1 PMID:26907264 -1.14.14.82 dihydrokaempferol fragaria x ananassa 81.4 81.4 1 PMID:25269395 -1.14.14.82 dihydrokaempferol tagetes erecta 12.5 12.5 1 PMID:25269395 -1.14.14.82 kaempferol arabidopsis thaliana 5.8 5.8 1 PMID:25269395 -1.14.14.82 kaempferol camellia sinensis 3.6e-07 3.6e-07 1 PMID:26907264 -1.14.14.82 kaempferol fragaria x ananassa 17.0 17.0 1 PMID:25269395 -1.14.14.82 kaempferol tagetes erecta 10.2 10.2 1 PMID:25269395 -1.14.14.82 naringenin arabidopsis thaliana 2.1 2.1 1 PMID:25269395 -1.14.14.82 naringenin camellia sinensis 8.2e-07 8.2e-07 1 PMID:26907264 -1.14.14.82 naringenin fragaria x ananassa 10.6 10.6 1 PMID:25269395 -1.14.14.82 naringenin tagetes erecta 17.0 17.0 1 PMID:25269395 -1.14.14.83 geraniol catharanthus roseus 2.8 1.4655 2 PMID:21504162;PMID:23933465 -1.14.14.84 nadh pseudomonas putida 43.0 32.0 3 PMID:2295633 -1.14.14.88 biochanin a medicago truncatula 0.1 0.1 1 PMID:14617078 -1.14.14.88 formononetin medicago truncatula 0.028 0.028 1 PMID:14617078 -1.14.14.9 (3,4-dihydroxyphenyl)acetate escherichia coli 2.1 2.1 1 PMID:31155821 -1.14.14.9 2-(4-hydroxyphenyl)ethanol escherichia coli 1.5 1.5 1 PMID:31155821 -1.14.14.9 3-hydroxyphenylacetate escherichia coli 4.4 4.4 1 PMID:31155821 -1.14.14.9 4-coumarate escherichia coli 0.6 0.6 1 PMID:31155821 -1.14.14.9 4-coumaric acid escherichia coli 0.387 0.387 1 PMID:31068633 -1.14.14.9 4-hydroxyphenylacetate acinetobacter baumannii 389.0 366.0 4 PMID:15451173 -1.14.14.9 4-hydroxyphenylacetate pseudomonas putida 0.833 0.833 1 PMID:8163477 -1.14.14.9 dl-4-hydroxymandelic acid escherichia coli 2.7 2.7 1 PMID:31155821 -1.14.14.9 methyl 4-hydroxybenzoate escherichia coli 0.2 0.2 1 PMID:31155821 -1.14.14.9 naringenin escherichia coli 0.15 0.15 1 PMID:31068633 -1.14.14.9 phenol escherichia coli 0.3 0.3 1 PMID:31155821 -1.14.14.9 resveratrol escherichia coli 0.437 0.437 1 PMID:31068633 -1.14.14.9 umbelliferone escherichia coli 0.418 0.418 1 PMID:31068633 -1.14.14.90 biochanin a medicago truncatula 0.033 0.033 1 PMID:14617078 -1.14.14.90 formononetin medicago truncatula 0.015 0.015 1 PMID:14617078 -1.14.14.91 7-ethoxycoumarin helianthus tuberosus 0.0567 0.0567 1 PMID:7925408 -1.14.14.91 7-methoxycoumarin helianthus tuberosus 0.19 0.19 1 PMID:7925408 -1.14.14.91 chlorotoluron helianthus tuberosus 0.000233 0.000233 1 PMID:7925408 -1.14.14.91 p-chloro-n-methylaniline helianthus tuberosus 2.37 2.37 1 PMID:7925408 -1.14.14.91 trans-cinnamate arabidopsis thaliana 1.72 1.72 1 PMID:17141284 -1.14.14.91 trans-cinnamate helianthus tuberosus 129.1 67.02499999999999 2 PMID:14725859;PMID:7925408 -1.14.14.91 trans-cinnamate ruta graveolens 161.8 161.8 1 PMID:14725859 -1.14.14.92 2-chlorobenzoate aspergillus niger 2.33 2.33 1 PMID:11594739 -1.14.14.92 2-fluorobenzoate aspergillus niger 4.33 4.33 1 PMID:11594739 -1.14.14.92 2-hydroxybenzoate aspergillus niger 4.17 4.17 1 PMID:11594739 -1.14.14.92 2-methylbenzoate aspergillus niger 3.67 3.67 1 PMID:11594739 -1.14.14.92 3-chlorobenzoate aspergillus niger 6.17 6.17 1 PMID:11594739 -1.14.14.92 3-fluorobenzoate aspergillus niger 4.83 4.83 1 PMID:11594739 -1.14.14.92 3-hydroxybenzoate aspergillus niger 4.5 4.5 1 PMID:11594739 -1.14.14.92 3-methoxybenzoate aspergillus niger 4.0 4.0 1 PMID:11594739 -1.14.14.92 3-methylbenzoate aspergillus niger 6.17 6.17 1 PMID:11594739 -1.14.14.92 benzoate aspergillus niger 4.5 4.0 3 PMID:11594739;PMID:8987724 -1.14.14.92 benzoate cystobasidium minutum 1.0 0.8335 2 PMID:8882724 -1.14.14.92 cinnamate cystobasidium minutum 0.005 0.005 1 PMID:8882724 -1.14.14.92 nicotinate aspergillus niger 4.0 4.0 1 PMID:11594739 -1.14.14.92 picolinate aspergillus niger 3.83 3.83 1 PMID:11594739 -1.14.15.1 (+)-camphor pseudomonas putida 51.0 12.63 9 PMID:17176102;PMID:18359283;PMID:32551522;PMID:6501299 -1.14.15.1 5,5-difluorocamphor pseudomonas putida 0.833 0.833 1 PMID:6501299 -1.14.15.1 cytochrome m pseudomonas putida 34.0 34.0 1 PMID:672627 -1.14.15.1 nadh pseudomonas putida 38.2 38.2 1 PMID:24302683 -1.14.15.1 o2 pseudomonas putida 66.0 60.5 2 PMID:14705955 -1.14.15.1 putidaredoxin pseudomonas putida 2.0 2.0 1 PMID:672627 -1.14.15.1 reduced putidaredoxin pseudomonas putida 64.0 60.2 2 PMID:28944003 -1.14.15.1 reduced putidaredoxin pseudomonas sp. tcu-hl1 12.6 11.5 2 PMID:32551522 -1.14.15.11 compactin streptomyces avermitilis 0.018 0.018 1 PMID:28274099 -1.14.15.11 diclofenac streptomyces avermitilis 0.36 0.36 1 PMID:28274099 -1.14.15.14 cholest-4-en-3-one mycobacterium tuberculosis 0.195 0.195 1 PMID:21983973 -1.14.15.14 farnesol mycobacterium tuberculosis 0.258 0.258 1 PMID:21983973 -1.14.15.15 (24s)-3beta-hydroxy-24-methyl-5alpha-cholesta-8(14),22-dien-15-one homo sapiens 0.0183 0.0183 1 PMID:18603016 -1.14.15.15 1alpha-hydroxyvitamin d3 rattus norvegicus 0.0233 0.012815 2 PMID:1880123;PMID:2013339 -1.14.15.15 3beta-hydroxy-5alpha-cholest-8(14)-en-15-one homo sapiens 0.073 0.073 1 PMID:18603016 -1.14.15.15 5beta-cholestane-3alpha,7alpha,12alpha-triol rattus norvegicus 0.6 0.592 3 PMID:1880123;PMID:2013339;PMID:2848026 -1.14.15.15 5beta-cholestane-3alpha,7alpha-diol rattus norvegicus 0.217 0.217 1 PMID:1880123;PMID:2848026 -1.14.15.15 cholesterol rattus norvegicus 0.0117 0.0117 1 PMID:2848026 -1.14.15.15 lumisterol3 homo sapiens 4560.0 4560.0 1 PMID:29452189 -1.14.15.16 1alpha,25-dihydroxyvitamin d3 homo sapiens 0.007 0.0045000000000000005 2 PMID:16617161;PMID:21058632 -1.14.15.16 1alpha,25-dihydroxyvitamin d3 rattus norvegicus 0.004 0.004 1 PMID:16617161 -1.14.15.16 2-methylene-19-nor-(20r)-1,25-dihydroxyvitamin d3 homo sapiens 0.0017 0.0017 1 PMID:21058632 -1.14.15.16 2-methylene-19-nor-(20s)-1,25-dihydroxyvitamin d3 homo sapiens 0.00025 0.00025 1 PMID:21058632 -1.14.15.16 25-hydroxyvitamin d3 homo sapiens 0.002 0.002 1 PMID:21058632 -1.14.15.18 (24r),25-dihydroxyvitamin d3 mus musculus 0.9 0.9 1 PMID:20193763 -1.14.15.18 1alpha-hydroxyvitamin d mus musculus 0.01 0.01 1 PMID:15972816 -1.14.15.18 20-hydroxyvitamin d3 mus musculus 0.14 0.14 1 PMID:20193763 -1.14.15.18 25-hydroxycholecalciferol rattus norvegicus 0.0733 0.0733 1 PMID:9426217 -1.14.15.18 25-hydroxyvitamin d mus musculus 0.385 0.385 1 PMID:15972816 -1.14.15.18 25-hydroxyvitamin d2 mus musculus 0.82 0.81 2 PMID:20193763 -1.14.15.18 25-hydroxyvitamin d3 mus musculus 0.92 0.8 2 PMID:20193763 -1.14.15.28 (25r)-25-bromo-27-norcholesterol mycobacterium tuberculosis 0.368 0.3335 2 PMID:22647881 -1.14.15.28 26-methylcholesterol mycobacterium tuberculosis 0.163 0.163 1 PMID:22647881 -1.14.15.28 cholest-4-en-3-one mycobacterium tuberculosis 1.4 1.4 1 PMID:20843794 -1.14.15.28 cholest-5-en-3-beta-ol mycobacterium tuberculosis 0.278 0.278 1 PMID:22647881 -1.14.15.28 cholesterol mycobacterium tuberculosis 0.278 0.278 1 PMID:20843794 -1.14.15.29 (25s)-25-bromo-27-norcholesterol mycobacterium tuberculosis 0.3 0.3 1 PMID:22647881 -1.14.15.29 26-methylcholesterol mycobacterium tuberculosis 0.317 0.317 1 PMID:22647881 -1.14.15.29 cholest-4-en-3-one mycobacterium tuberculosis 2.92 2.92 1 PMID:20843794 -1.14.15.29 cholest-5-en-3-beta-ol mycobacterium tuberculosis 0.467 0.467 1 PMID:22647881 -1.14.15.29 cholesterol mycobacterium tuberculosis 0.47 0.47 1 PMID:20843794 -1.14.15.3 arachidonic acid homo sapiens 0.00917 0.005835 2 PMID:7679927 -1.14.15.3 arachidonic acid oryctolagus cuniculus 0.783 0.75 2 PMID:11106489 -1.14.15.3 laurate homo sapiens 0.245 0.245 1 PMID:10860550 -1.14.15.3 laurate oryctolagus cuniculus 0.767 0.442 2 PMID:11106489 -1.14.15.3 lauric acid homo sapiens 0.163 0.08575 2 PMID:7679927 -1.14.15.3 palmitate homo sapiens 0.013 0.013 1 PMID:10860550 -1.14.15.3 palmitic acid homo sapiens 0.0367 0.023600000000000003 2 PMID:7679927 -1.14.15.3 pga1 homo sapiens 0.00133 0.00133 1 PMID:7679927 -1.14.15.3 prostaglandin e1 oryctolagus cuniculus 0.383 0.28300000000000003 2 PMID:11106489 -1.14.15.30 1,4-androstadiene-3,17-dione mycobacterium tuberculosis 0.8 0.8 1 PMID:19234303 -1.14.15.30 1,4-androstadiene-3,17-dione rhodococcus rhodochrous 1.3 1.0 2 PMID:25049233 -1.14.15.30 3-oxo-23,24-bisnorchol-4-en-22-oate rhodococcus rhodochrous 2.6 1.6 4 PMID:25049233 -1.14.15.30 3-oxo-23,24-bisnorchol-4-en-22-oic acid mycobacterium tuberculosis 0.08 0.08 1 PMID:21987574 -1.14.15.30 3-oxo-23,24-bisnorchol-4-en-22-oic acid-coa mycobacterium tuberculosis 0.61 0.61 1 PMID:21987574 -1.14.15.30 3-oxo-23,24-bisnorchola-1,4-dien-22-oate-coa rhodococcus rhodochrous 1.7 1.4 2 PMID:25049233 -1.14.15.30 3-oxo-23,24-bisnorchola-1,4-dien-22-oic acid mycobacterium tuberculosis 0.25 0.25 1 PMID:21987574 -1.14.15.30 3-oxo-23,24-bisnorchola-1,4-dien-22-oic acid-coa mycobacterium tuberculosis 2.7 2.7 1 PMID:21987574 -1.14.15.30 3-oxo-23,24-bisnorchola-1,4-diene-22-oate rhodococcus rhodochrous 0.9 0.7 4 PMID:25049233 -1.14.15.30 3-oxo-23,24-bisnorchola-1,4-diene-22-oyl-coa rhodococcus rhodochrous 1.7 1.4 2 PMID:25049233 -1.14.15.30 3-oxo-23,24-bisnorcholesta-1,4-dien-22-oate mycobacterium tuberculosis 0.25 0.25 2 PMID:21987574 -1.14.15.30 3-oxo-23,24-bisnorcholesta-1,4-dien-22-oate-coa mycobacterium tuberculosis 2.7 2.7 2 PMID:21987574 -1.14.15.30 3-oxo-23,24-bisnorcholesta-4-ene-22-oate mycobacterium tuberculosis 0.08 0.08 2 PMID:21987574 -1.14.15.30 3-oxo-23,24-bisnorcholesta-4-ene-22-oyl-coa mycobacterium tuberculosis 0.61 0.61 2 PMID:21987574 -1.14.15.30 4-androstene-3,17-dione mycobacterium tuberculosis 0.07 0.07 4 PMID:19234303;PMID:21987574 -1.14.15.30 4-estren-3,17-dione rhodococcus rhodochrous 0.8 0.65 4 PMID:25049233 -1.14.15.30 5alpha-androstan-3,17-dione rhodococcus rhodochrous 0.8 0.8 1 PMID:25049233 -1.14.15.30 androsta-1,4-diene-3,17-dione mycobacterium tuberculosis 0.8 0.8 3 PMID:21987574 -1.14.15.30 androsta-1,4-diene-3,17-dione rhodococcus rhodochrous 1.3 1.0 2 PMID:25049233 -1.14.15.30 o2 mycobacterium tuberculosis 7.0 4.75 2 PMID:19234303;PMID:21987574 -1.14.15.30 o2 rhodococcus rhodochrous 1.7 1.25 4 PMID:25049233 -1.14.15.30 testosterone rhodococcus rhodochrous 1.4 1.1 4 PMID:25049233 -1.14.15.32 (+/-)-pentalenene streptomyces avermitilis 0.00838 0.00838 1 PMID:17017767 -1.14.15.35 6-deoxyerythronolide b actinopolyspora erythraea 0.00728 0.00728 1 PMID:35174640 -1.14.15.35 6-deoxyerythronolide b aeromicrobium erythreum 0.00757 0.00757 1 PMID:35174640 -1.14.15.35 6-deoxyerythronolide b saccharopolyspora erythraea 0.00719 0.00719 1 PMID:35174640 -1.14.15.36 lanosterol nocardia farcinica 21.9 16.7 3 PMID:22038382 -1.14.15.4 11-deoxycorticosterone bos taurus 1.83 0.583 5 PMID:2337351;PMID:708075;PMID:7556158 -1.14.15.4 11-deoxycorticosterone homo sapiens 2.68 0.7 4 PMID:18215163;PMID:31296661;PMID:34485929 -1.14.15.4 11-deoxycortisol curvularia lunata 3.45 3.45 1 PMID:8268203 -1.14.15.4 11-deoxycortisol homo sapiens 2.16 0.14950000000000002 4 PMID:18215163;PMID:34485929 -1.14.15.4 adrenal ferredoxin homo sapiens 1.48 1.24 2 PMID:18215163 -1.14.15.4 corticosterone bos taurus 0.0378 0.0378 1 PMID:7556158 -1.14.15.5 corticosterone homo sapiens 0.0473 0.0473 1 PMID:31296661 -1.14.15.6 20-hydroxyvitamin d3 bos taurus 0.123 0.123 1 PMID:18573681 -1.14.15.6 cholesterol bos taurus 0.5 0.174 4 PMID:18573681;PMID:2605191;PMID:3968069;PMID:7599132 -1.14.15.6 vitamin d3 bos taurus 1.6 0.9640000000000001 2 PMID:18573681 -1.14.15.8 reduced ferredoxin priestia megaterium 3.3 3.3 1 PMID:19635596 -1.14.15.8 reduced flavodoxin priestia megaterium 1.34 1.34 1 PMID:19635596 -1.14.16.1 5,6,7,8-tetrahydrobiopterin chromobacterium violaceum 0.2 0.2 1 PMID:19664549 -1.14.16.1 6,7-dimethyl-5,6,7,8-tetrahydrobiopterin chromobacterium violaceum 6.0 6.0 1 PMID:12459906 -1.14.16.1 6,7-dimethyltetrahydropterin chromobacterium violaceum 1.4 1.4 1 PMID:18817418 -1.14.16.1 6-methyltetrahydropterin chromobacterium violaceum 1.6 1.6 1 PMID:18817418 -1.14.16.1 l-phenylalanine chromobacterium violaceum 18.0 9.965 2 PMID:19664549;PMID:23860686 -1.14.16.1 l-phenylalanine dictyostelium discoideum 8.93 7.775 2 PMID:23017206 -1.14.16.1 l-phenylalanine pseudomonas fluorescens 1.75 1.75 1 PMID:34868217 -1.14.16.1 l-phenylalanine rattus norvegicus 9.7 9.7 1 PMID:26823465 -1.14.16.1 l-tryptophan chromobacterium violaceum 0.4 0.4 1 PMID:19664549 -1.14.16.1 phenylalanine homo sapiens 6.58 1.445 6 PMID:9022714;PMID:9434741 -1.14.16.1 phenylalanine rattus norvegicus 16.0 12.54 2 PMID:10933781;PMID:7407194 -1.14.16.2 l-tyrosine homo sapiens 3.33 3.1799999999999997 2 PMID:15468323;PMID:16878998 -1.14.16.2 l-tyrosine rattus norvegicus 2.5 2.5 1 PMID:21302933 -1.14.16.2 tetrahydrobiopterin homo sapiens 0.58 0.47 3 PMID:21235236 -1.14.16.4 2-azaisotryptophan oryctolagus cuniculus 0.217 0.217 1 PMID:10587452 -1.14.16.4 4-azatryptophan oryctolagus cuniculus 0.358 0.358 1 PMID:10587452 -1.14.16.4 4-methyltryptophan oryctolagus cuniculus 0.273 0.273 1 PMID:10587452 -1.14.16.4 6-azatryptophan oryctolagus cuniculus 0.533 0.533 1 PMID:10587452 -1.14.16.4 6-methyltryptophan oryctolagus cuniculus 0.0733 0.0733 1 PMID:10587452 -1.14.16.4 7-azatryptophan oryctolagus cuniculus 0.252 0.252 1 PMID:10587452 -1.14.16.4 7-methyltryptophan oryctolagus cuniculus 0.315 0.315 1 PMID:10587452 -1.14.16.4 l-tryptophan gallus gallus 32.0 32.0 1 PMID:18055219 -1.14.16.4 l-tryptophan homo sapiens 5.03 3.85 2 PMID:19816759 -1.14.16.4 l-tryptophan oryctolagus cuniculus 0.207 0.207 1 PMID:10587452 -1.14.16.4 l-tryptophan pseudomonas fluorescens 0.5 0.5 1 PMID:34868217 -1.14.16.4 o2 gallus gallus 22.8 22.8 1 PMID:18055219 -1.14.16.4 o2 homo sapiens 6.73 4.0565 2 PMID:19816759 -1.14.16.4 tetrahydrobiopterin gallus gallus 43.0 43.0 1 PMID:18055219 -1.14.16.4 tetrahydrobiopterin homo sapiens 4.567 3.367 2 PMID:19816759 -1.14.16.7 2-fluoro-dl-phenylalanine streptomyces coeruleorubidus 0.167 0.167 1 PMID:31318464 -1.14.16.7 4-fluoro-dl-phenylalanine streptomyces coeruleorubidus 0.233 0.233 1 PMID:31318464 -1.14.16.7 6-methyltetrahydropterin streptomyces coeruleorubidus 0.021 0.021 1 PMID:21615132 -1.14.16.7 [3,5-d2]-l-phenylalanine streptomyces coeruleorubidus 0.56 0.56 1 PMID:31318464 -1.14.16.7 l-phenylalanine streptomyces coeruleorubidus 1.25 0.63 3 PMID:21615132;PMID:31318464 -1.14.17.1 1-(4-hydroxybenzyl)imidazole bos taurus 9.5 9.5 1 PMID:3593236 -1.14.17.1 1-phenyl-1-aminomethylethene bos taurus 10.0 10.0 1 PMID:6860408 -1.14.17.1 1-phenylethylamine bos taurus 65.0 65.0 1 PMID:6860408 -1.14.17.1 2-(4-hydroxphenyl)prop-2-enylamine bos taurus 56.0 56.0 1 PMID:3593236 -1.14.17.1 2-bromo-3-(p-hydroxyphenyl)-1-propene bos taurus 0.223 0.223 1 PMID:6477886 -1.14.17.1 2-chlorophenethylamine bos taurus 1.1 1.1 1 PMID:7059582 -1.14.17.1 2-hydroxyphenethylamine bos taurus 4.2 4.2 1 PMID:7059582 -1.14.17.1 2-phenylprop-2-enylamine bos taurus 14.0 14.0 1 PMID:3593236 -1.14.17.1 3-phenylpropylamine bos taurus 20.4 16.2 2 PMID:3593236;PMID:6860408 -1.14.17.1 4-hydroxy-alpha-methylstyrene bos taurus 0.7 0.7 1 PMID:3593236 -1.14.17.1 dopamine bos taurus 110.0 61.5 2 PMID:3593236;PMID:7059582 -1.14.17.1 n-phenylethylenediamine bos taurus 21.0 21.0 1 PMID:3593236 -1.14.17.1 octopamine bos taurus 33.0 33.0 1 PMID:6860408 -1.14.17.1 phenylacetaldehyde bos taurus 1.7 1.7 1 PMID:3782127 -1.14.17.1 phenylaminoethyl sulfide bos taurus 68.0 53.5 2 PMID:3593236;PMID:6860408 -1.14.17.1 tyramine bos taurus 121.0 121.0 1 PMID:3593236 -1.14.17.3 (25r)-3beta-hydroxycholest-5-en-27-oate rattus norvegicus 5.0 5.0 1 PMID:16330540 -1.14.17.3 acetyl-l-tyr-l-phe-gly xenopus laevis 0.02 0.02 1 PMID:3745173 -1.14.17.3 alpha-hydroxyhippuric acid cricetulus griseus 51.0 51.0 1 PMID:17176064 -1.14.17.3 d-tyr-val-gly xenopus laevis 0.13 0.13 1 PMID:12509982 -1.14.17.3 dansyl-gly-gly-ser-co-nh-ch2-cooh rattus norvegicus 17.0 17.0 1 PMID:15479039 -1.14.17.3 dansyl-l-tyr-l-val-gly homo sapiens 13.8 13.8 1 PMID:23530865 -1.14.17.3 hippuric acid rattus norvegicus 39.1 32.05 2 PMID:12590568 -1.14.17.3 hippuric acid xenopus laevis 0.02 0.02 1 PMID:12509982 -1.14.17.3 hooc-nh-ch2-cooh rattus norvegicus 37.0 37.0 1 PMID:15479039 -1.14.17.3 n-acetyl-tyr-val-gly rattus norvegicus 15.0 7.765 2 PMID:12795609 -1.14.17.3 n-benzoylglycine rattus norvegicus 14.5 8.75 2 PMID:12105892 -1.14.17.3 n-dansyl-l-tyr-l-val-gly bos taurus 0.143 0.143 1 * -1.14.17.3 n-dansyl-l-tyr-l-val-gly rattus norvegicus 9.2 9.2 1 PMID:16330540 -1.14.17.3 n-dansyl-l-tyr-l-val-gly sus scrofa 0.983 0.983 1 PMID:3778444 -1.14.17.3 n-dansyl-tyr-val-gly homo sapiens 0.35 0.35 1 PMID:22554821 -1.14.17.3 n-dansyl-tyr-val-gly rattus norvegicus 5.0 5.0 1 PMID:3341777 -1.14.17.3 n-trinitrophenyl-d-tyr-val-gly xenopus laevis 1.4 1.4 1 PMID:12509982 -1.14.17.4 1-aminocyclopropane-1-carboxylate malus domestica 0.07 0.07 1 PMID:11361015 -1.14.17.4 1-aminocyclopropane-1-carboxylate solanum lycopersicum 5.9 0.4175 4 PMID:18238897;PMID:22711330;PMID:9398335 -1.14.17.4 1-aminocyclopropane-1-carboxylic acid malus domestica 0.0914 0.066 3 PMID:19223050 -1.14.17.4 alpha-aminoisobutyrate malus domestica 0.07 0.07 1 PMID:11361015 -1.14.17.4 ascorbate solanum lycopersicum 0.2 0.2 1 PMID:22711330 -1.14.18.1 2-methylresorcinol agaricus bisporus 9.94 9.94 1 PMID:27480027 -1.14.18.1 3,4-dihydroxyphenyl propionic acid agaricus bisporus 632.0 593.0 2 PMID:10691963 -1.14.18.1 3,4-dihydroxyphenylacetic acid agaricus bisporus 433.1 433.1 1 PMID:18647136 -1.14.18.1 3,4-dihydroxyphenylacetic acid homo sapiens 5.9 5.9 1 PMID:25189462 -1.14.18.1 3,4-dihydroxyphenylacetic acid streptomyces antibioticus 113.0 113.0 1 PMID:25189462 -1.14.18.1 3,4-dihydroxyphenylpropionic acid agaricus bisporus 607.2 607.2 1 PMID:18647136 -1.14.18.1 3-(3,4-dihydroxyphenyl) propionic acid pholiota microspora 544.0 544.0 1 PMID:17617709 -1.14.18.1 3-(3,5-dihydroxyphenyl)-1-propanoic acid streptomyces antibioticus 3.0 3.0 1 PMID:25189462 -1.14.18.1 3-[2-(3,4-dihydroxyphenyl)ethylaminocarbonyl]-3-methyl-1-(4-ethoxycarbonylphenyl)triazene agaricus bisporus 6.0 6.0 1 PMID:19386398 -1.14.18.1 3-[2-(4-hydroxyphenyl)ethylaminocarbonyl]-3-methyl-1-(4-cyanophenyl)triazene agaricus bisporus 0.6 0.6 1 PMID:19386398 -1.14.18.1 3-chlorophenol streptomyces antibioticus 0.9 0.9 1 PMID:20875779 -1.14.18.1 3-fluorophenol streptomyces antibioticus 3.0 3.0 1 * -1.14.18.1 3-hydroxybenzyl alcohol agaricus bisporus 12.1 12.1 1 * -1.14.18.1 3-methoxyphenol agaricus bisporus 46.8 46.8 1 * -1.14.18.1 4-bromophenol agaricus bisporus 6.9 6.9 1 PMID:22732412 -1.14.18.1 4-bromophenol ralstonia solanacearum 8.97 8.97 1 PMID:29691629 -1.14.18.1 4-chlorocatechol agaricus bisporus 859.2 859.2 1 PMID:18647136 -1.14.18.1 4-chlorocatechol thermothelomyces thermophilus 5.69 5.550000000000001 2 PMID:30266731;PMID:33741634 -1.14.18.1 4-chlorophenol agaricus bisporus 4.6 4.6 1 PMID:22732412 -1.14.18.1 4-chlorophenol ralstonia solanacearum 7.37 7.37 1 PMID:29691629 -1.14.18.1 4-chlorophenol streptomyces antibioticus 5.6 5.6 1 PMID:20875779 -1.14.18.1 4-ethoxyphenol agaricus bisporus 202.2 167.1 2 PMID:22732412;PMID:27480027 -1.14.18.1 4-ethylcatechol agaricus bisporus 802.3 802.3 1 PMID:18647136 -1.14.18.1 4-ethylresorcinol agaricus bisporus 6.0 6.0 1 PMID:27480027 -1.14.18.1 4-fluorophenol agaricus bisporus 10.54 10.54 1 PMID:22732412 -1.14.18.1 4-fluorophenol ralstonia solanacearum 10.3 10.3 1 PMID:29691629 -1.14.18.1 4-fluorophenol streptomyces antibioticus 10.5 10.5 1 * -1.14.18.1 4-hydroxyanisole agaricus bisporus 274.9 184.2 3 PMID:10691963;PMID:22732412;PMID:26450473 -1.14.18.1 4-hydroxybenzaldehyde agaricus bisporus 0.19 0.19 1 PMID:22732412 -1.14.18.1 4-hydroxybenzyl alcohol agaricus bisporus 88.2 69.1 2 * -1.14.18.1 4-hydroxyphenyl propionic acid agaricus bisporus 66.7 66.7 1 * -1.14.18.1 4-hydroxyphenyl propionic acid streptomyces glaucescens 134.0 134.0 1 * -1.14.18.1 4-hydroxyphenyl acetic acid agaricus bisporus 44.3 44.3 1 PMID:10691963 -1.14.18.1 4-hydroxyphenyl acetic acid neurospora crassa 250.0 250.0 1 * -1.14.18.1 4-hydroxyphenyl acetic acid streptomyces glaucescens 48.8 48.8 1 * -1.14.18.1 4-hydroxyphenyl propionic acid agaricus bisporus 66.7 66.7 1 PMID:10691963 -1.14.18.1 4-hydroxyphenylpropionic acid streptomyces antibioticus 66.7 54.85 2 PMID:16342125 -1.14.18.1 4-iodophenol agaricus bisporus 2.73 2.73 1 PMID:22732412 -1.14.18.1 4-iodophenol ralstonia solanacearum 21.73 21.73 1 PMID:29691629 -1.14.18.1 4-methoxyphenol agaricus bisporus 184.2 184.1 2 PMID:27480027 -1.14.18.1 4-methylcatechol agaricus bisporus 842.1 842.05 2 PMID:10691963;PMID:18647136 -1.14.18.1 4-methylcatechol homo sapiens 12.0 12.0 1 PMID:25189462 -1.14.18.1 4-methylcatechol spinacia oleracea 7220.0 7220.0 1 * -1.14.18.1 4-methylcatechol terfezia arenaria 807.33 807.33 1 PMID:31778703 -1.14.18.1 4-methylphenol agaricus bisporus 14.76 14.76 1 PMID:22732412 -1.14.18.1 4-methylresorcinol agaricus bisporus 7.73 7.73 1 PMID:27480027 -1.14.18.1 4-nitrocatechol agaricus bisporus 0.9 0.9 1 PMID:18647136 -1.14.18.1 4-t-butylcatechol pholiota microspora 294.0 294.0 1 PMID:17617709 -1.14.18.1 4-t-butylphenol pholiota microspora 13.2 13.2 1 PMID:17617709 -1.14.18.1 4-tert-butylcatechol agaricus bisporus 642.0 641.05 2 PMID:10691963;PMID:18647136 -1.14.18.1 4-tert-butylcatechol homo sapiens 20.5 20.5 1 PMID:25189462 -1.14.18.1 4-tert-butylcatechol streptomyces antibioticus 1650.0 1650.0 1 PMID:25189462 -1.14.18.1 4-tert-butylphenol agaricus bisporus 5.61 5.61 1 PMID:22732412 -1.14.18.1 alpha-arbutin agaricus bisporus 4.43 4.43 1 PMID:28493937 -1.14.18.1 beta-arbutin agaricus bisporus 3.77 3.7350000000000003 2 PMID:28493937;PMID:29136639 -1.14.18.1 caffeic acid agaricus bisporus 164.46 164.46 1 PMID:32337685 -1.14.18.1 caffeic acid spinacia oleracea 1450.0 1450.0 1 * -1.14.18.1 caffeic acid uncultured bacterium 630.0 630.0 1 PMID:34156250 -1.14.18.1 catechin thermothelomyces thermophilus 40.48 33.735 2 PMID:30266731;PMID:33741634 -1.14.18.1 catechol agaricus bisporus 1080.0 878.0 3 PMID:10691963;PMID:18647136;PMID:28500345 -1.14.18.1 catechol homo sapiens 44.0 44.0 1 PMID:25189462 -1.14.18.1 catechol spinacia oleracea 2960.0 2960.0 1 * -1.14.18.1 catechol streptomyces antibioticus 80.0 80.0 1 PMID:25189462 -1.14.18.1 catechol terfezia arenaria 1011.2 1011.2 1 PMID:31778703 -1.14.18.1 catechol thermothelomyces thermophilus 2.19 1.165 2 PMID:30266731;PMID:33741634 -1.14.18.1 chlorogenic acid agaricus bisporus 105.6 105.6 1 PMID:32337685 -1.14.18.1 chlorogenic acid spinacia oleracea 1650.0 1650.0 1 * -1.14.18.1 cryptochlorogenic acid agaricus bisporus 9.82 9.82 1 PMID:32337685 -1.14.18.1 d-ascorbic acid agaricus bisporus 0.92 0.92 1 PMID:19010454 -1.14.18.1 d-dopa priestia megaterium 12.12 6.35 3 PMID:19672047 -1.14.18.1 d-dopa streptomyces sp. 117.0 117.0 1 PMID:10737179 -1.14.18.1 d-tyr agaricus bisporus 8.0 8.0 1 * -1.14.18.1 d-tyr neurospora crassa 160.0 160.0 1 * -1.14.18.1 d-tyrosine ralstonia solanacearum 0.3 0.3 1 PMID:23381872 -1.14.18.1 d-tyrosine streptomyces sp. 2.27 2.27 1 PMID:10737179 -1.14.18.1 deoxyarbutin agaricus bisporus 1.95 1.95 1 PMID:29136639 -1.14.18.1 digallol terfezia arenaria 670.68 670.68 1 PMID:31778703 -1.14.18.1 diphenol helix vulgaris 4.48 4.48 1 PMID:18162195 -1.14.18.1 dl-2-methyltyrosine agaricus bisporus 0.6 0.6 1 * -1.14.18.1 dl-dopa streptomyces sp. 1170.0 1170.0 1 PMID:10737179 -1.14.18.1 dl-tyrosine streptomyces sp. 74.2 74.2 1 PMID:10737179 -1.14.18.1 dopa spinacia oleracea 4940.0 4940.0 1 * -1.14.18.1 dopa xenopus laevis 26.7 26.7 1 PMID:3930497 -1.14.18.1 dopa methyl ester agaricus bisporus 35.5 35.5 1 PMID:10691963 -1.14.18.1 dopamine agaricus bisporus 2540.0 1489.5 2 PMID:10691963;PMID:28500345 -1.14.18.1 dopamine homo sapiens 61.0 61.0 1 PMID:25189462 -1.14.18.1 dopamine palinurus elephas 144.0 139.5 2 PMID:18422877 -1.14.18.1 dopamine pholiota microspora 1590.0 1590.0 1 PMID:17617709 -1.14.18.1 dopamine streptomyces antibioticus 439.0 210.0 5 PMID:16342125;PMID:25189462 -1.14.18.1 dopamine uncultured bacterium 320.0 320.0 1 PMID:34156250 -1.14.18.1 esculetin agaricus bisporus 928.0 739.5 2 PMID:17284853 -1.14.18.1 esculetin spinacia oleracea 123.0 123.0 1 * -1.14.18.1 gallic acid agaricus bisporus 28.2 28.2 1 PMID:18647136 -1.14.18.1 gallic acid uncultured bacterium 7.7 7.7 1 PMID:34156250 -1.14.18.1 gly-gly-l-tyr agaricus bisporus 3.0 3.0 1 * -1.14.18.1 gly-gly-l-tyr trichoderma reesei 7.2 7.2 1 * -1.14.18.1 gly-l-tyr-gly agaricus bisporus 3.1 3.1 1 * -1.14.18.1 gly-l-tyr-gly trichoderma reesei 4.2 4.2 1 * -1.14.18.1 guaiacol thermothelomyces thermophilus 2.91 1.7850000000000001 2 PMID:30266731;PMID:33741634 -1.14.18.1 h2o2 streptomyces refuineus 1.5 1.5 1 PMID:21919439 -1.14.18.1 hydrocaffeic acid spinacia oleracea 4630.0 4630.0 1 * -1.14.18.1 hydroquinone agaricus bisporus 101.5 101.5 1 PMID:27480027 -1.14.18.1 hydroquinone thermothelomyces thermophilus 1.69 1.41 2 PMID:30266731;PMID:33741634 -1.14.18.1 hydroxyhydroquinone agaricus bisporus 229.0 229.0 1 PMID:24578277 -1.14.18.1 l-alpha-methyl tyrosine agaricus bisporus 0.6 0.6 1 PMID:10691963 -1.14.18.1 l-alpha-methyldopa agaricus bisporus 44.3 44.3 1 PMID:10691963 -1.14.18.1 l-ascorbic acid agaricus bisporus 0.97 0.97 1 PMID:19010454 -1.14.18.1 l-dopa agaricus bisporus 1810.0 958.5 2 PMID:10691963;PMID:28500345 -1.14.18.1 l-dopa armillaria ostoyae 178.0 178.0 1 PMID:33741625 -1.14.18.1 l-dopa colocasia esculenta 7100.0 7100.0 1 PMID:32676302 -1.14.18.1 l-dopa dioscorea alata 219000.0 219000.0 1 PMID:32676302 -1.14.18.1 l-dopa dioscorea cayenensis subsp. rotundata 17000.0 17000.0 1 PMID:32676302 -1.14.18.1 l-dopa dioscorea praehensilis 45000.0 45000.0 1 PMID:32676302 -1.14.18.1 l-dopa helix vulgaris 1.8 1.8 1 PMID:18162195 -1.14.18.1 l-dopa homo sapiens 38.1 38.1 1 PMID:25189462 -1.14.18.1 l-dopa juglans regia 199.3 199.3 1 PMID:24613318 -1.14.18.1 l-dopa neurospora crassa 317.0 317.0 1 * -1.14.18.1 l-dopa pholiota microspora 478.0 478.0 1 PMID:17617709 -1.14.18.1 l-dopa priestia aryabhattai 3.755 3.755 1 PMID:33571594 -1.14.18.1 l-dopa priestia megaterium 21.3 15.795 4 PMID:19672047;PMID:23305929 -1.14.18.1 l-dopa streptomyces antibioticus 197.0 107.4 5 PMID:16342125;PMID:25189462 -1.14.18.1 l-dopa streptomyces castaneoglobisporus 880.0 880.0 1 PMID:15003252 -1.14.18.1 l-dopa streptomyces sp. 1120.0 619.0 2 PMID:10737179;PMID:3928616 -1.14.18.1 l-dopa thermothelomyces thermophilus 0.11 0.09 2 PMID:30266731;PMID:33741634 -1.14.18.1 l-dopa trametes sanguinea 84.85 84.85 1 PMID:15659188 -1.14.18.1 l-dopa uncultured bacterium 520.0 520.0 1 PMID:34156250 -1.14.18.1 l-dopa vibrio tyrosinaticus 90.0 82.5 2 PMID:4208174 -1.14.18.1 l-dopa vitis vinifera 72.12 72.12 1 PMID:25863609 -1.14.18.1 l-dopa methyl ester homo sapiens 57.0 57.0 1 PMID:25189462 -1.14.18.1 l-dopa methyl ester streptomyces antibioticus 187.0 187.0 1 PMID:25189462 -1.14.18.1 l-isoproterenol agaricus bisporus 29.4 29.4 1 PMID:10691963 -1.14.18.1 l-isoproterenol homo sapiens 2.28 2.28 1 PMID:25189462 -1.14.18.1 l-isoproterenol streptomyces antibioticus 5.8 5.8 1 PMID:25189462 -1.14.18.1 l-tyr agaricus bisporus 7.9 7.9 1 * -1.14.18.1 l-tyr neurospora crassa 320.0 320.0 1 * -1.14.18.1 l-tyr trametes sanguinea 40.9 40.9 1 PMID:15659188 -1.14.18.1 l-tyr-gly-gly agaricus bisporus 4.0 4.0 1 * -1.14.18.1 l-tyr-gly-gly trichoderma reesei 3.2 3.2 1 * -1.14.18.1 l-tyrosinase mushroom 19.5 11.0 2 * -1.14.18.1 l-tyrosine agaricus bisporus 7.9 5.835 2 PMID:26450473;PMID:27480027;PMID:28500345 -1.14.18.1 l-tyrosine armillaria ostoyae 188.0 188.0 1 PMID:33741625 -1.14.18.1 l-tyrosine homo sapiens 2.6 2.6 1 PMID:25189462 -1.14.18.1 l-tyrosine juglans regia 20.8 20.8 1 PMID:24613318 -1.14.18.1 l-tyrosine priestia aryabhattai 2.545 2.545 1 PMID:33571594 -1.14.18.1 l-tyrosine priestia megaterium 4.0 2.5 3 PMID:19672047;PMID:23305929 -1.14.18.1 l-tyrosine ralstonia solanacearum 1.42 1.42 1 PMID:23381872 -1.14.18.1 l-tyrosine streptomyces antibioticus 7.9 7.9 1 PMID:25189462 -1.14.18.1 l-tyrosine streptomyces glaucescens 13.2 13.2 1 * -1.14.18.1 l-tyrosine streptomyces refuineus 0.576 0.576 1 PMID:21919439 -1.14.18.1 l-tyrosine streptomyces sp. 81.4 44.300000000000004 2 PMID:10737179;PMID:3928616 -1.14.18.1 l-tyrosine terfezia arenaria 524.6 524.6 1 PMID:31778703 -1.14.18.1 l-tyrosine uncultured bacterium 4.8 4.8 1 PMID:34156250 -1.14.18.1 l-tyrosine vibrio tyrosinaticus 100.0 100.0 1 PMID:4208174 -1.14.18.1 l-tyrosine xenopus laevis 3.33 3.33 1 PMID:3930497 -1.14.18.1 l-tyrosine methyl ester agaricus bisporus 3.4 3.4 1 * -1.14.18.1 l-tyrosine methyl ester streptomyces glaucescens 235.0 235.0 1 * -1.14.18.1 methyl 3-hydroxy-l-tyrosinate streptomyces antibioticus 8.9 3.4 3 PMID:16342125 -1.14.18.1 methyl gallate agaricus bisporus 80.2 80.2 1 PMID:18647136 -1.14.18.1 neochlorogenic acid agaricus bisporus 22.18 22.18 1 PMID:32337685 -1.14.18.1 o-diphenol rapana venosa 3.5 3.08 2 PMID:18162195 -1.14.18.1 oxyresveratrol agaricus bisporus 5.39 5.39 1 PMID:26450473 -1.14.18.1 p-coumaric acid uncultured bacterium 2.6 2.6 1 PMID:34156250 -1.14.18.1 p-cresol pholiota microspora 107.0 107.0 1 PMID:17617709 -1.14.18.1 phenol agaricus bisporus 14.36 12.7 3 PMID:22732412;PMID:27480027;PMID:28500345 -1.14.18.1 phenol streptomyces sp. 3.2 3.2 1 PMID:3928616 -1.14.18.1 protocatechuic acid agaricus bisporus 8.1 8.1 1 PMID:18647136 -1.14.18.1 protocatechuic acid spinacia oleracea 860.0 860.0 1 * -1.14.18.1 protocatechuic acid uncultured bacterium 59.0 59.0 1 PMID:34156250 -1.14.18.1 protocatechuic aldehyde agaricus bisporus 1.5 1.5 1 PMID:18647136 -1.14.18.1 protocatechuic aldehyde spinacia oleracea 336.0 336.0 1 * -1.14.18.1 pyrogallol agaricus bisporus 1280.0 1280.0 1 PMID:18647136 -1.14.18.1 pyrogallol streptomyces sp. 9.7 9.7 1 PMID:3928616 -1.14.18.1 resorcinol agaricus bisporus 18.34 18.34 1 PMID:27480027 -1.14.18.1 tyramine agaricus bisporus 25.9 20.75 2 PMID:10691963;PMID:28500345 -1.14.18.1 tyramine neurospora crassa 160.0 160.0 1 * -1.14.18.1 tyramine palinurus elephas 5.0 5.0 2 PMID:18422877 -1.14.18.1 tyramine streptomyces antibioticus 25.9 7.4 3 PMID:16342125 -1.14.18.1 tyramine uncultured bacterium 6.3 6.3 1 PMID:34156250 -1.14.18.1 tyramine vitis vinifera 2.88 2.88 1 PMID:25863609 -1.14.18.1 tyrosine mus musculus 0.0217 0.0167 2 PMID:415664 -1.14.18.1 vanillin thermothelomyces thermophilus 1.92 1.92 1 PMID:30266731 -1.14.19.1 n-hydroxy-benzenecarboximidamide sus scrofa 1.9e-06 1.9e-06 1 PMID:18609446 -1.14.19.1 stearoyl-acyl-carrier protein spinacia oleracea 0.5 0.5 1 * -1.14.19.1 stearoyl-coa rattus norvegicus 0.35 0.35 2 PMID:27698;PMID:4373719 -1.14.19.11 oleoyl-[acyl-carrier protein] hedera helix 0.004 0.004 1 PMID:15939740 -1.14.19.11 palmitoleoyl-[acyl-carrier protein] hedera helix 0.048 0.048 1 PMID:15939740 -1.14.19.11 palmitoyl-[acyl-carrier protein] hedera helix 0.25 0.25 1 PMID:15939740 -1.14.19.11 stearoyl-[acyl-carrier protein] hedera helix 0.17 0.17 1 PMID:15939740 -1.14.19.2 10-(heptyloxy)-decanoyl-[acyl-carrier protein] ricinus communis 0.5 0.5 1 PMID:12146979 -1.14.19.2 7-(decyloxy)-heptanoyl-[acyl-carrier protein] ricinus communis 0.2 0.2 1 PMID:12146979 -1.14.19.2 8-(nonyloxy)-octanoyl-[acyl-carrier protein] ricinus communis 0.04 0.04 1 PMID:12146979 -1.14.19.2 9-(octyloxy)-nonanoyl-[acyl-carrier protein] ricinus communis 0.02 0.02 1 PMID:12146979 -1.14.19.2 heptadecanoyl-[acyl-carrier protein] ricinus communis 0.233 0.233 1 PMID:10504253 -1.14.19.2 hexadecanoyl-[acyl-carrier protein] ricinus communis 0.095 0.07085 2 PMID:10504253;PMID:11294879 -1.14.19.2 nonadecanoyl-[acyl-carrier protein] ricinus communis 0.2 0.2 1 PMID:10504253 -1.14.19.2 octadecanoyl-[acyl-carrier protein] ricinus communis 0.817 0.705 3 PMID:10504253;PMID:11294879;PMID:12146979 -1.14.19.2 pentadecanoyl-[acyl-carrier protein] ricinus communis 0.0317 0.0317 1 PMID:10504253 -1.14.19.2 stearoyl-[acyl-carrier protein] ricinus communis 0.5 0.5 1 PMID:9778341 -1.14.19.2 tetradecanoyl-[acyl-carrier protein] ricinus communis 0.817 0.00717 3 PMID:10504253;PMID:11294879 -1.14.19.25 alpha-linolenoyl-coa mortierella alpina 0.367 0.367 1 PMID:29082420 -1.14.19.25 arachidonoyl-coa mortierella alpina 0.045 0.045 1 PMID:29082420 -1.14.19.25 linoleoyl-coa mortierella alpina 0.187 0.187 1 PMID:29082420 -1.14.19.41 beta-sitosterol arabidopsis thaliana 0.17 0.009 3 PMID:16531502;PMID:17073785 -1.14.19.41 beta-sitosterol physcomitrium patens 0.015 0.015 1 PMID:19306103 -1.14.19.41 beta-sitosterol solanum lycopersicum 0.17 0.17 1 PMID:16531502 -1.14.19.49 (4s)-tetracycline kitasatospora aureofaciens 0.0085 0.0085 1 PMID:23800859 -1.14.19.50 (r)-coclaurine narcissus aff. pseudonarcissus mk-2014 0.035 0.035 1 PMID:26941773 -1.14.19.50 (s)-coclaurine narcissus aff. pseudonarcissus mk-2014 0.022 0.022 1 PMID:26941773 -1.14.19.50 4'-o-methyl-n-methylnorbelladine narcissus aff. pseudonarcissus mk-2014 0.041 0.041 1 PMID:26941773 -1.14.19.50 4'-o-methylnorbelladine narcissus aff. pseudonarcissus mk-2014 0.25 0.25 1 PMID:26941773 -1.14.19.53 all-trans-retinal homo sapiens 0.004 0.004 1 PMID:27059013 -1.14.19.53 all-trans-retinaldehyde homo sapiens 0.0045 0.0045 1 PMID:34480899 -1.14.19.53 all-trans-retinaldehyde from cellular retinol-binding protein-1 homo sapiens 0.0033 0.0033 1 PMID:34480899 -1.14.19.53 all-trans-retinoic acid homo sapiens 0.023 0.0166 2 PMID:27059013;PMID:34480899 -1.14.19.53 all-trans-retinoic acid from cellular retinoic acid-binding protein-1 homo sapiens 0.00107 0.00107 1 PMID:34480899 -1.14.19.53 all-trans-retinoic acid from cellular retinoic acid-binding protein-2 homo sapiens 0.0065 0.0065 1 PMID:34480899 -1.14.19.53 all-trans-retinol homo sapiens 0.38 0.068 3 PMID:27059013;PMID:28701464;PMID:34480899 -1.14.19.53 all-trans-retinol from cellular retinol-binding protein-1 homo sapiens 0.0045 0.0045 1 PMID:34480899 -1.14.19.58 anthranilamide streptomyces toxytricini 0.02 0.02 1 PMID:26840773 -1.14.19.58 kynurenine streptomyces toxytricini 0.0085 0.0085 1 PMID:26840773 -1.14.19.58 l-tryptophan streptomyces rugosporus 0.00813 0.00813 1 PMID:15850981 -1.14.19.58 l-tryptophan xenorhabdus szentirmaii 0.074 0.074 2 PMID:31673806 -1.14.19.59 anthranilamide streptomyces toxytricini 0.02 0.02 1 PMID:26840773 -1.14.19.59 kynurenine streptomyces toxytricini 0.0085 0.0085 1 PMID:26840773 -1.14.19.59 l-tryptophan streptomyces albogriseolus 0.047 0.047 1 * -1.14.19.59 l-tryptophan streptomyces toxytricini 0.0255 0.01815 2 PMID:21424165;PMID:26840773 -1.14.19.59 l-tryptophan uncultured bacterium 0.074 0.074 1 PMID:31692209 -1.14.19.60 7-chloro-l-tryptophan kutzneria sp. 744 0.023 0.023 1 PMID:18828589 -1.14.19.60 l-tryptophan kutzneria sp. 744 0.0013 0.0013 1 PMID:18828589 -1.14.19.67 (r)-reticuline papaver somniferum 0.027 0.027 1 PMID:19567876 -1.14.19.69 flaviolin streptomyces coelicolor 0.017 0.017 1 PMID:15659395 -1.14.19.79 (22r,23r)-22,23-dihydroxycampesterol arabidopsis thaliana 0.0018 0.0018 1 PMID:22822057 -1.14.19.79 (22s)-22-hydroxycampesterol arabidopsis thaliana 0.012 0.012 1 PMID:22822057 -1.14.19.8 pentalenolactone f streptomyces arenae 8.8 4.415 2 PMID:21284395;PMID:27588339 -1.14.19.8 pentalenolactone f streptomyces exfoliatus 10.5 10.5 1 PMID:21284395 -1.14.19.9 (25r)-3beta-hydroxycholest-5-en-27-oate pseudomonas fluorescens 0.0018 0.0018 1 * -1.14.19.9 6-chloro-l-tryptophan kutzneria sp. 744 0.0012 0.0012 1 PMID:18828589 -1.14.19.9 fadh2 lentzea aerocolonigenes 0.12 0.066 2 PMID:16784243 -1.14.19.9 l-tryptophan kutzneria sp. 744 0.0032 0.0032 1 PMID:18828589 -1.14.19.9 l-tryptophan lentzea aerocolonigenes 0.023 0.023 1 PMID:15743914 -1.14.19.9 tryptophan lentzea aerocolonigenes 0.05 0.05 1 PMID:16784243 -1.14.19.9 tryptophan pseudomonas fluorescens 0.11 0.11 1 PMID:21404376 -1.14.20.1 acetyl-6-aminopenicillanic acid streptomyces clavuligerus 0.06 0.06 1 PMID:19277744 -1.14.20.1 adipyl 6-aminopenicillanic acid streptomyces clavuligerus 0.073 0.073 1 PMID:10222202 -1.14.20.1 ampicillin streptomyces clavuligerus 0.12 0.0365 4 PMID:12631288;PMID:18083859;PMID:19277744 -1.14.20.1 penicillin g hapsidospora chrysogena 0.077 0.073 4 PMID:14734549;PMID:15869968;PMID:21190060 -1.14.20.1 penicillin g streptomyces clavuligerus 0.079 0.05 12 PMID:10222202;PMID:11352583;PMID:12047382;PMID:12631288;PMID:12676714;PMID:15381427;PMID:19277744;PMID:21909691;PMID:22923414 -1.14.20.1 penicillin n streptomyces clavuligerus 0.42 0.307 5 PMID:10222202;PMID:11352583;PMID:12047382;PMID:12676714;PMID:19277744 -1.14.20.10 2-oxoglutarate xenorhabdus nematophila 5.1 5.1 1 PMID:25866990 -1.14.20.14 12-epi-fischerindole u fischerella ambigua 1.7 1.7 1 PMID:27027281 -1.14.20.14 12-epi-fischerindole u hapalosiphon welwitschii 1.8 1.8 1 PMID:27027281 -1.14.20.14 12-epi-hapalindole c fischerella ambigua 0.71 0.71 1 PMID:27027281 -1.14.20.14 12-epi-hapalindole c hapalosiphon welwitschii 0.73 0.73 1 PMID:27027281 -1.14.20.14 ambiguine c fischerella ambigua 0.7 0.7 1 PMID:27027281 -1.14.20.14 ambiguine h fischerella ambigua 0.68 0.68 1 PMID:27027281 -1.14.20.14 ambiguine i fischerella ambigua 0.68 0.68 1 PMID:27027281 -1.14.20.14 ambiguine l fischerella ambigua 0.67 0.67 1 PMID:27027281 -1.14.20.14 hapalindole u fischerella ambigua 0.21 0.21 1 PMID:27027281 -1.14.20.5 naringenin plagiochasma appendiculatum 0.027 0.027 1 PMID:24859082 -1.14.20.6 dihydrokaempferol camellia sinensis 0.12 0.12 1 PMID:33180711 -1.14.20.6 dihydrokaempferol zea mays 6.6 6.6 1 PMID:20059741 -1.14.20.6 dihydrokampferol camellia sinensis 0.28 0.14850000000000002 2 PMID:33180711 -1.14.20.6 dihydromyricetin camellia sinensis 0.06 0.06 1 PMID:33180711 -1.14.20.6 dihydroquercetin arabidopsis thaliana 0.056 0.056 1 PMID:17719613 -1.14.20.6 dihydroquercetin camellia sinensis 0.74 0.255 4 PMID:17629496;PMID:33180711 -1.14.20.6 dihydroquercetin zea mays 3.9 3.9 1 PMID:20059741 -1.14.20.7 2-oxoadipate pseudomonas savastanoi pv. phaseolicola 0.0042 0.0042 1 PMID:27749027 -1.14.20.7 2-oxoglutarate pseudomonas savastanoi pv. phaseolicola 2.067 2.067 1 PMID:27749027 -1.14.20.7 2-oxoglutarate pseudomonas syringae 0.5 0.5 1 * -1.14.20.7 l-arginine pseudomonas savastanoi pv. phaseolicola 0.048 0.02625 2 PMID:27749027 -1.14.20.9 2-oxoglutarate erwinia amylovora 0.22 0.22 1 PMID:25866990 -1.14.20.9 2-oxoglutarate pseudomonas aeruginosa 2.3 2.3 1 PMID:25866990 -1.14.99.12 testololactone ilyonectria destructans 0.45 0.45 1 PMID:3486864 -1.14.99.15 4-methoxybenzoate arthrobacter sp. 0.056 0.056 1 * -1.14.99.15 4-methoxybenzoate rhodopseudomonas palustris 37.9 37.9 1 PMID:22695988 -1.14.99.20 phe-leu-glu-glu-leu bos taurus 0.00667 0.00667 1 PMID:2780546 -1.14.99.50 hercynine chloracidobacterium thermophilum 0.292 0.291 2 PMID:32257583 -1.14.99.52 d-histidine erwinia tasmaniensis 0.78 0.78 1 PMID:23877651 -1.14.99.52 histamine erwinia tasmaniensis 0.36 0.36 1 PMID:23877651 -1.14.99.52 l-cysteine erwinia tasmaniensis 3.3 3.3 1 PMID:23877651 -1.14.99.52 l-histidinamide erwinia tasmaniensis 0.57 0.57 1 PMID:23877651 -1.14.99.52 l-histidine erwinia tasmaniensis 3.4 3.4 1 PMID:23877651 -1.14.99.54 2,6-dimethoxyphenol talaromyces amestolkiae 0.96 0.68 3 PMID:34948409 -1.14.99.54 cellulose thermothelomyces thermophilus 0.021 0.021 1 PMID:29100178 -1.14.99.54 cellulose thermothielavioides terrestris 0.015 0.015 1 PMID:29100178 -1.14.99.54 cellulose trichoderma reesei 0.021 0.021 1 PMID:29100178 -1.14.99.54 h2o2 talaromyces amestolkiae 0.25 0.17 3 PMID:34948409 -1.14.99.56 2,6-dimethoxyphenol talaromyces amestolkiae 0.96 0.68 3 PMID:34948409 -1.14.99.56 cellotetraose panus similis 0.11 0.11 1 PMID:26928935 -1.14.99.56 h2o2 talaromyces amestolkiae 0.25 0.17 3 PMID:34948409 -1.14.99.66 [histone h3 peptide 21mer p16a]-n6-methyl-l-lysine4 mus musculus 0.0043 0.0043 1 PMID:19407342 -1.14.99.66 [histone h3 peptide 21mer]-n6,n6-dimethyl-l-lysine4-dimethyl-l-lysine9 mus musculus 0.0222 0.0222 1 PMID:19407342 -1.14.99.66 [histone h3 peptide 21mer]-n6-methyl-l-lysine4 mus musculus 0.033 0.0188 2 PMID:19407342 -1.14.99.66 [histone h3 peptide 21mer]-n6-methyl-l-lysine4-acetyl-l-lysine9 mus musculus 0.0058 0.0058 1 PMID:19407342 -1.14.99.66 [histone h3 peptide 21mer]-n6-methyl-l-lysine4-methyl-l-arginine17 mus musculus 0.005 0.005 1 PMID:19407342 -1.14.99.66 [histone h3 peptide 21mer]-n6-methyl-l-lysine4-methyl-l-lysine9 mus musculus 0.004 0.004 1 PMID:19407342 -1.14.99.66 [histone h3 peptide 30mer]-n6-methyl-l-lysine4 mus musculus 0.0068 0.0068 1 PMID:19407342 -1.14.99.66 [histone h3]-n6,n6-dimethyl-l-lysine4 arabidopsis thaliana 0.011 0.011 1 PMID:18393445 -1.14.99.66 [histone h3]-n6,n6-l-dimethyllysine21 homo sapiens 0.051 0.051 1 PMID:17569509 -1.14.99.66 [histone h3]-n6,n6-l-dimethyllysine4-1-21 homo sapiens 0.159 0.157 3 PMID:26673564 -1.14.99.66 [histone h3]-n6-methyl-l-lysine4 arabidopsis thaliana 0.008 0.008 1 PMID:18393445 -1.14.99.66 h3k4me2 homo sapiens 0.082 0.082 1 PMID:29869982 -1.14.99.66 h3k4me2 (1-21 aa) peptide homo sapiens 0.199 0.199 1 PMID:19408960 -1.14.99.66 h3k4me2 1-21 peptide homo sapiens 0.159 0.0875 6 PMID:26673564;PMID:29869982 -1.14.99.66 h3k4me2k14ac homo sapiens 0.004 0.004 1 PMID:29869982 -1.14.99.66 h3k4me2k18ac homo sapiens 0.072 0.072 1 PMID:29869982 -1.14.99.66 h3k4me2k9ac homo sapiens 0.025 0.025 1 PMID:29869982 -1.14.99.68 4-aminobenzoate streptomyces thioluteus 0.104 0.104 1 PMID:18458342 -1.14.99.69 i6a-acsltrp salmonella enterica subsp. enterica serovar typhimurium 0.1 0.1 1 PMID:25453905 -1.15.1.1 o2- homo sapiens 40000.0 22300.0 2 * -1.15.1.1 o2.- bos taurus 100000.0 100000.0 1 PMID:236750 -1.15.1.1 superoxide avicennia marina 107000.0 107000.0 1 PMID:28720545 -1.16.1.1 hg2+ bacillus sp. (in: firmicutes) 12.0 9.0 3 PMID:16114877 -1.16.1.1 hg2+ escherichia coli 13.5 10.465 2 PMID:1531297 -1.16.1.1 hg2+ lysinibacillus sphaericus 17.7 17.7 1 PMID:28894951 -1.16.1.1 hg2+ pseudomonas aeruginosa 0.7 0.7 1 PMID:6436233 -1.16.1.1 hg2+ uncultured pseudomonadota bacterium 12.25 12.25 1 PMID:30446558 -1.16.1.1 hgcl2 acidithiobacillus ferrooxidans 12.4 12.4 1 * -1.16.1.8 2,6-dichlorophenolindophenol homo sapiens 0.43 0.43 1 PMID:12416982 -1.16.1.8 3-acetylpyridine adenine dinucleotide phosphate homo sapiens 0.86 0.86 1 PMID:12416982 -1.16.1.8 doxorubicin homo sapiens 1.61 1.61 1 PMID:12416982 -1.16.1.8 ferricyanide homo sapiens 8.24 8.24 1 PMID:12416982 -1.16.1.8 menadione homo sapiens 1.61 1.61 1 PMID:12416982 -1.16.1.8 nadph homo sapiens 7.2 5.5600000000000005 2 PMID:17892308;PMID:24589657 -1.16.1.9 fe(iii)-citrate synechocystis sp. 1.11 0.675 2 PMID:21221720 -1.16.1.9 fe(iii)-edta synechocystis sp. 2.0 1.475 2 PMID:21221720 -1.16.2.1 cr6+ shewanella oneidensis 10.2 5.699999999999999 2 PMID:21498755 -1.16.3.1 4-phenylenediamine homo sapiens 0.48 0.48 1 PMID:22961397 -1.16.3.1 fe(ii) escherichia coli 3.9 3.9 1 PMID:21903583 -1.16.3.1 fe(ii) homo sapiens 0.505 0.505 1 PMID:14623105 -1.16.3.1 fe(ii) saccharomyces cerevisiae 1.07 0.865 2 PMID:14623105;PMID:17042492 -1.16.3.1 fe2+ candida albicans 1.06 1.06 1 PMID:21645130 -1.16.3.1 fe2+ homo sapiens 0.3 0.3 1 PMID:22961397 -1.16.3.1 fe2+ saccharomyces cerevisiae 0.78 0.78 1 PMID:12684851 -1.16.3.1 hydroquinone saccharomyces cerevisiae 2.2 1.5250000000000001 2 PMID:12684851;PMID:17042492 -1.16.3.1 p-phenylenediamine saccharomyces cerevisiae 0.92 0.92 1 PMID:12684851 -1.16.3.3 mn2+ bacillus pumilus 0.32 0.32 1 PMID:23577125 -1.16.3.4 2,2'-azino-bis(3-ethylbenzthiazoline)-6-sulphonic acid rhodococcus erythropolis 22.15 22.15 1 PMID:23485678 -1.16.3.4 [cu(i)(bicinchoninate)2]3- desulfovibrio sp. a2 0.128 0.128 1 PMID:28749328 -1.16.3.4 [cu(i)(mecn4)]pf6+ salmonella enterica subsp. enterica serovar typhimurium 9.3 9.3 1 PMID:20231415 -1.16.3.4 cu+ escherichia coli 15.87 13.04 4 PMID:15516598;PMID:21903583 -1.16.3.4 cu+ homo sapiens 0.375 0.375 1 PMID:14623105 -1.16.3.4 cu+ rhodococcus erythropolis 0.155 0.155 1 PMID:23485678 -1.16.3.4 cu+ saccharomyces cerevisiae 1.32 1.32 1 PMID:14623105 -1.16.3.4 fe2+ desulfovibrio sp. a2 3.0 3.0 1 PMID:28749328 -1.16.3.4 fe2+ escherichia coli 3.58 3.58 1 PMID:15516598 -1.16.3.4 fe2+ salmonella enterica subsp. enterica serovar typhimurium 16.12 16.12 1 PMID:20231415 -1.17.1.10 nad+ burkholderia stabilis 1.66 1.66 1 * -1.17.1.10 nad+ granulicella mallensis 5.77 5.77 1 PMID:26104866 -1.17.1.10 nadp+ burkholderia stabilis 4.75 4.75 1 * -1.17.1.10 nadp+ granulicella mallensis 3.96 3.96 1 PMID:26104866 -1.17.1.3 4beta-(s-cysteinyl)-catechin vitis vinifera 0.0648 0.058249999999999996 2 PMID:31092697 -1.17.1.3 4beta-(s-cysteinyl)-epicatechin vitis vinifera 0.0123 0.01055 2 PMID:31092697 -1.17.1.4 2,6-dichlorophenolindophenol veillonella atypica 5.67 5.67 1 PMID:6061702 -1.17.1.4 benzaldehyde escherichia coli 1097.0 351.5 4 PMID:27622978 -1.17.1.4 cytochrome c veillonella atypica 0.717 0.717 1 PMID:6061702 -1.17.1.4 ferredoxin veillonella atypica 20.2 20.2 1 PMID:6061702 -1.17.1.4 ferricyanide veillonella atypica 18.2 18.2 1 PMID:6061702 -1.17.1.4 hypoxanthine homo sapiens 30.0 30.0 1 PMID:17301077 -1.17.1.4 hypoxanthine veillonella atypica 0.75 0.75 1 PMID:6061702 -1.17.1.4 nad+ rhodobacter capsulatus 111.0 111.0 1 * -1.17.1.4 nitro blue tetrazolium veillonella atypica 9.55 9.55 1 PMID:6061702 -1.17.1.4 oxygen veillonella atypica 0.8 0.8 1 PMID:6061702 -1.17.1.4 purine veillonella atypica 0.7 0.7 1 PMID:6061702 -1.17.1.4 salicylaldehyde veillonella atypica 0.1 0.1 1 PMID:6061702 -1.17.1.4 xanthine acinetobacter baumannii 25.0 25.0 1 PMID:27537049 -1.17.1.4 xanthine bos taurus 15.0 10.665 2 PMID:1328233 -1.17.1.4 xanthine delftia acidovorans 120.0 86.0 9 PMID:14622263;PMID:8611534 -1.17.1.4 xanthine drosophila melanogaster 31.0 24.9 3 PMID:11829759;PMID:1313286;PMID:8774727 -1.17.1.4 xanthine homo sapiens 18.33 9.659999999999998 2 PMID:17301077 -1.17.1.4 xanthine rhodobacter capsulatus 108.0 85.25 4 PMID:15265866;PMID:18390908 -1.17.1.4 xanthine veillonella atypica 2.5 2.5 1 PMID:6061702 -1.17.1.8 (2s,4s)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate neisseria meningitidis 77.0 60.0 2 PMID:29187521 -1.17.1.8 (2s,4s)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate selaginella moellendorffii 63.0 56.0 2 PMID:29187521 -1.17.1.8 (2s,4s)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate staphylococcus aureus 21.0 20.5 2 PMID:22776412 -1.17.1.8 (2s,4s)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate vitis vinifera 21.0 17.5 2 PMID:29187521 -1.17.1.8 2,3-dihydrodipicolinate thermotoga maritima 19.0 13.55 2 PMID:18250105 -1.17.1.8 nadh corynebacterium glutamicum 1.9 1.9 1 PMID:29574741 -1.17.1.8 nadh escherichia coli 5.9 5.9 1 PMID:29574741 -1.17.1.8 nadh staphylococcus aureus 21.0 20.5 2 PMID:22776412 -1.17.1.8 nadh thermotoga maritima 0.49 0.2915 2 PMID:18250105 -1.17.1.8 nadph corynebacterium glutamicum 5.1 5.1 1 PMID:29574741 -1.17.1.8 nadph escherichia coli 2.7 2.7 1 PMID:29574741 -1.17.1.8 nadph thermotoga maritima 17.0 9.8 2 PMID:18250105 -1.17.1.9 co2 clostridium ljungdahlii 0.012 0.012 1 PMID:29504829 -1.17.1.9 co2 cupriavidus necator 10.0 10.0 1 * -1.17.1.9 co2 desulfovibrio desulfuricans 46.6 46.6 1 PMID:27348246 -1.17.1.9 co2 rhodobacter capsulatus 1.5 1.5 1 PMID:24034888 -1.17.1.9 co2 thermochaetoides thermophila 0.032 0.032 1 PMID:32557118 -1.17.1.9 co2 thermothelomyces thermophilus 0.1 0.1 2 * -1.17.1.9 formate [candida] boidinii 1100.0 1.78 7 PMID:25346488;PMID:27100912;PMID:27198726;PMID:29083897;PMID:33043425;PMID:34632901 -1.17.1.9 formate [candida] methylica 2910.0 1.2 9 PMID:15266119;PMID:17479216;PMID:27847673;PMID:27887026;PMID:30321426;PMID:33043425;PMID:34632901 -1.17.1.9 formate ancylobacter aquaticus 6100.0 5600.0 2 PMID:33043425 -1.17.1.9 formate citrobacter sp. 76.0 76.0 1 PMID:24751436 -1.17.1.9 formate clostridium ljungdahlii 0.246 0.246 1 PMID:29504829 -1.17.1.9 formate cupriavidus necator 201.0 201.0 1 * -1.17.1.9 formate desulfovibrio desulfuricans 543.0 543.0 1 PMID:27348246 -1.17.1.9 formate gelatoporia subvermispora 5600.0 4900.0 2 PMID:33043425 -1.17.1.9 formate glycine max 2.9 2.9 2 PMID:23100543;PMID:26483960 -1.17.1.9 formate gossypium hirsutum 0.295 0.2925 2 PMID:29556429;PMID:33754169 -1.17.1.9 formate lotus japonicus 1.3 1.3 1 PMID:19281876 -1.17.1.9 formate moraxella sp. 6100.0 5600.0 3 PMID:19966418;PMID:33043425 -1.17.1.9 formate ogataea angusta 2.32 2.32 1 PMID:23715855 -1.17.1.9 formate paracoccus sp. (in: a-proteobacteria) 6.1 6.1 1 PMID:15734738 -1.17.1.9 formate paracoccus sp. 12-a 1980.0 1805.0 2 PMID:33043425 -1.17.1.9 formate pseudomonas sp. 10.0 10.0 1 PMID:11825616 -1.17.1.9 formate rhodobacter capsulatus 39.7 35.95 4 PMID:24034888;PMID:27054466 -1.17.1.9 formate saccharomyces cerevisiae 900.0 870.0 2 PMID:33043425 -1.17.1.9 formate thermochaetoides thermophila 2310.0 1.3075 8 PMID:27887026;PMID:30321426;PMID:31030612;PMID:33043425;PMID:34632901 -1.17.1.9 formate thermothelomyces thermophilus 1290.0 0.32 5 PMID:33043425;PMID:34632901 -1.17.1.9 formate thiobacillus sp. 1.77 1.77 1 PMID:25061666 -1.17.1.9 formate thiobacillus sp. knk65ma 7460.0 6100.0 3 PMID:33043425;PMID:34632901 -1.17.1.9 formate xanthobacter sp. 91 31.0 15.7 2 PMID:31182484 -1.17.1.9 glyoxylate paracoccus sp. (in: a-proteobacteria) 0.007 0.007 1 PMID:15734738 -1.17.1.9 hco3- [candida] boidinii 0.015 0.015 1 PMID:34632901 -1.17.1.9 hco3- [candida] methylica 0.01 0.008 3 PMID:27887026;PMID:30321426;PMID:34632901 -1.17.1.9 hco3- cupriavidus oxalaticus 3.0 3.0 1 PMID:34632901 -1.17.1.9 hco3- thermochaetoides thermophila 0.069 0.024 4 PMID:27887026;PMID:30321426;PMID:32557118;PMID:34632901 -1.17.1.9 hco3- thermothelomyces thermophilus 0.1 0.1 1 PMID:34632901 -1.17.1.9 hco3- thiobacillus sp. knk65ma 0.32 0.32 1 PMID:34632901 -1.17.1.9 nad+ [candida] boidinii 29200.0 5.6 11 PMID:18616465;PMID:27100912;PMID:27198726;PMID:27836850;PMID:29083897;PMID:33043425 -1.17.1.9 nad+ [candida] methylica 2040.0 1.4 6 PMID:27847673;PMID:30321426;PMID:33043425 -1.17.1.9 nad+ ancylobacter aquaticus 1760.0 1675.0 2 PMID:33043425 -1.17.1.9 nad+ bacillus sp. (in: firmicutes) 6.67 6.67 1 PMID:21848698 -1.17.1.9 nad+ clostridium ljungdahlii 0.499 0.499 1 PMID:29504829 -1.17.1.9 nad+ cupriavidus necator 201.0 201.0 1 * -1.17.1.9 nad+ gelatoporia subvermispora 3960.0 3380.0 2 PMID:33043425 -1.17.1.9 nad+ glycine max 2.9 2.9 2 PMID:23100543;PMID:26878574 -1.17.1.9 nad+ gossypium hirsutum 0.759 0.759 1 PMID:29556429 -1.17.1.9 nad+ lotus japonicus 1.2 1.2 1 PMID:19281876 -1.17.1.9 nad+ moraxella sp. 6720.0 5460.0 2 PMID:33043425 -1.17.1.9 nad+ moraxella sp. c-1 7.3 7.3 1 PMID:25927002 -1.17.1.9 nad+ paracoccus sp. 12-a 2160.0 1920.0 2 PMID:33043425 -1.17.1.9 nad+ pseudomonas sp. 7.3 7.3 1 PMID:26878574 -1.17.1.9 nad+ pseudomonas sp. 101 7.3 7.3 1 PMID:25927002 -1.17.1.9 nad+ saccharomyces cerevisiae 30200.0 29800.0 3 PMID:12144528;PMID:33043425 -1.17.1.9 nad+ thermochaetoides thermophila 1140.0 0.65 5 PMID:31030612;PMID:33043425 -1.17.1.9 nad+ thermothelomyces thermophilus 1680.0 815.38 4 PMID:33043425 -1.17.1.9 nad+ thiobacillus sp. knk65ma 2920.0 2660.0 2 PMID:33043425 -1.17.1.9 nad+ xanthobacter sp. 91 31.0 31.0 1 PMID:31182484 -1.17.1.9 nadh clostridium carboxidivorans 0.08 0.08 1 PMID:23144135 -1.17.1.9 nadh cupriavidus necator 10.0 10.0 1 * -1.17.1.9 nadh thermothelomyces thermophilus 0.03 0.03 2 * -1.17.1.9 nadp+ [candida] boidinii 4e-05 4e-05 3 PMID:18616465 -1.17.1.9 nadp+ bacillus sp. (in: firmicutes) 1.07 1.07 1 PMID:21848698 -1.17.1.9 nadp+ gossypium hirsutum 0.0083 0.0083 1 PMID:29556429 -1.17.1.9 nadp+ lotus japonicus 0.005 0.005 1 PMID:19281876 -1.17.1.9 nadp+ xanthobacter sp. 91 0.4 0.4 1 PMID:31182484 -1.17.1.9 reduced 1,1'-diaminoethyl-4,4'-bipyridinium salt [candida] boidinii 0.072 0.072 1 * -1.17.1.9 reduced 1,1'-dicarboxyl-4,4'-bipyridinium salt [candida] boidinii 0.005 0.005 1 * -1.17.1.9 reduced 1-methyl-1'-aminoethyl-4,4'-bipyridinium salt [candida] boidinii 0.038 0.038 1 * -1.17.1.9 reduced 1-methyl-1'-carboxymethyl-4,4'-bipyridinium salt [candida] boidinii 0.025 0.025 1 * -1.17.1.9 reduced methyl viologen [candida] boidinii 0.032 0.032 1 * -1.17.2.2 lupanine pseudomonas sp. 217.0 119.15 2 PMID:12686118;PMID:1656935 -1.17.2.2 sparteine pseudomonas sp. 11.8 11.8 1 PMID:12686118 -1.17.2.3 ferri-ssc desulfovibrio desulfuricans 27.0 27.0 1 PMID:22526566 -1.17.2.3 ferri-tpic3 desulfovibrio desulfuricans 17.1 17.1 1 PMID:22526566 -1.17.2.3 ferricytochrome c-553 desulfovibrio desulfuricans 239.0 239.0 1 PMID:22526566 -1.17.2.3 formate nitratidesulfovibrio vulgaris 1.85 1.85 1 PMID:9654061 -1.17.3.2 2-mercaptopurine bos taurus 1.98 1.98 1 PMID:17367294 -1.17.3.2 2-thioxanthine bos taurus 3.32 3.32 1 PMID:17367294 -1.17.3.2 6-mercaptopurine bos taurus 0.13 0.13 1 PMID:17367294 -1.17.3.2 6-thioxanthine bos taurus 2.76 2.76 1 PMID:17367294 -1.17.3.2 hypoxanthine bos taurus 4.35 4.35 1 PMID:13313312 -1.17.3.2 hypoxanthine homo sapiens 30.0 30.0 1 PMID:17301077 -1.17.3.2 nadph bos taurus 2.57 1.9249999999999998 2 PMID:13313312 -1.17.3.2 xanthine acinetobacter calcoaceticus 20.0 20.0 1 PMID:30926462 -1.17.3.2 xanthine bos taurus 108.0 10.725 4 PMID:13313312;PMID:20050623 -1.17.3.2 xanthine cellulosimicrobium funkei 1.4 1.4 1 PMID:33090589 -1.17.3.2 xanthine homo sapiens 18.3 18.3 1 PMID:17301077 -1.17.3.2 xanthine rhodobacter capsulatus 135.0 135.0 1 PMID:25258317 -1.17.3.5 4-oxocyclohexane-1-carboxylate sinomonas cyclohexanicum 44.0 44.0 1 PMID:34583900 -1.17.4.1 cdp escherichia coli 12.9 8.115 2 PMID:2180924 -1.17.4.1 cdp falseniella ignava 8.2 8.2 1 PMID:31414238 -1.17.4.1 cdp mus musculus 0.29 0.21000000000000002 4 PMID:11781084 -1.17.4.2 atp lactobacillus leichmannii 0.0145 0.0145 1 PMID:10431931 -1.17.4.2 ctp lactobacillus leichmannii 0.03 0.0208 4 PMID:10431931 -1.17.4.2 gtp oshimavirus p7426 47.6 47.6 1 PMID:34314684 -1.17.4.2 utp lactobacillus leichmannii 0.0158 0.0158 1 PMID:10431931 -1.17.4.4 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone homo sapiens 0.0072 0.0072 1 PMID:23772386 -1.17.5.1 phenylacetyl-coa thauera aromatica 12.0 12.0 1 PMID:10336636 -1.17.5.2 caffeine pseudomonas sp. 0.167 0.167 1 PMID:17981969 -1.17.5.3 formate escherichia coli 563.0 563.0 1 PMID:1099093 -1.17.7.4 (e)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate aquifex aeolicus 3.7 3.7 1 PMID:12482608 -1.17.7.4 (e)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate burkholderia glumae 3.11 2.11 2 * -1.17.9.1 4-cresol pseudomonas putida 121.0 121.0 3 PMID:15147198;PMID:15301551;PMID:15643899 -1.17.98.4 formate escherichia coli 2833.0 2833.0 1 PMID:1906883 -1.17.98.5 co2 acetobacterium woodii 28.22 28.22 1 PMID:24337298 -1.17.98.5 co2 thermoanaerobacter kivui 2654.0 1337.99 2 PMID:30186365;PMID:39551789 -1.17.98.5 formate thermoanaerobacter kivui 2748.0 1375.69 2 PMID:30186365;PMID:39551789 -1.17.99.10 7-dehydrocholesterol sterolibacterium denitrificans 0.33 0.33 1 PMID:29921665 -1.17.99.10 beta-sitost-4-en-3-one sterolibacterium denitrificans 0.14 0.14 1 PMID:29921665 -1.17.99.10 campest-4-en-3-one sterolibacterium denitrificans 0.17 0.094 2 PMID:29921665 -1.17.99.10 cholest-4-en-3-one sterolibacterium denitrificans 1.11 0.29 3 PMID:29921665 -1.17.99.10 vitamin d3 sterolibacterium denitrificans 0.23 0.23 1 PMID:29921665 -1.17.99.2 3-phenyl-1-propene aromatoleum aromaticum 0.64 0.55 2 PMID:24998764 -1.17.99.2 3-phenyl-1-propyne aromatoleum aromaticum 0.33 0.31 2 PMID:24998764 -1.17.99.2 ethylbenzene aromatoleum aromaticum 0.27 0.22000000000000003 2 PMID:24998764 -1.18.1.1 desulfovibrio gigas rubredoxin megalodesulfovibrio gigas 8.42 8.42 1 PMID:8375383 -1.18.1.2 1,4-benzoquinone rhodopseudomonas palustris 130.0 130.0 1 PMID:35624864 -1.18.1.2 1,4-naphthoquinone rhodopseudomonas palustris 110.0 110.0 1 PMID:35624864 -1.18.1.2 2,4,6-trinitrotoluene rhodopseudomonas palustris 1.93 1.93 1 PMID:35624864 -1.18.1.2 2,6-dichlorophenolindophenol chlamydomonas reinhardtii 37.0 36.0 2 * -1.18.1.2 2,6-dichlorophenolindophenol mycobacterium tuberculosis 25.6 23.3 2 PMID:12071965 -1.18.1.2 2,6-dimethyl-1,4-benzoquinone rhodopseudomonas palustris 52.1 52.1 1 PMID:35624864 -1.18.1.2 2-dinitrobenzene rhodopseudomonas palustris 0.48 0.48 1 PMID:35624864 -1.18.1.2 2-hydroxy-1,4-naphthoquinone rhodopseudomonas palustris 0.26 0.26 1 PMID:35624864 -1.18.1.2 2-methyl-1,4-benzoquinone rhodopseudomonas palustris 130.0 130.0 1 PMID:35624864 -1.18.1.2 2-methyl-1,4-naphthoquinone rhodopseudomonas palustris 21.6 21.6 1 PMID:35624864 -1.18.1.2 2-methyl-3-hydroxy-1,4-naphthoquinone rhodopseudomonas palustris 1.35 1.35 1 PMID:35624864 -1.18.1.2 3,5-dinitrobenzoic acid rhodopseudomonas palustris 0.09 0.09 1 PMID:35624864 -1.18.1.2 3-dinitrobenzene rhodopseudomonas palustris 0.42 0.42 1 PMID:35624864 -1.18.1.2 4-dinitrobenzene rhodopseudomonas palustris 2.21 2.21 1 PMID:35624864 -1.18.1.2 4-nitroacetophenone rhodopseudomonas palustris 0.3 0.3 1 PMID:35624864 -1.18.1.2 4-nitrobenzaldehyde rhodopseudomonas palustris 0.97 0.97 1 PMID:35624864 -1.18.1.2 4-nitrobenzyl alcohol rhodopseudomonas palustris 0.23 0.23 1 PMID:35624864 -1.18.1.2 5,8-dihydroxy-1,4-naphthoquinone rhodopseudomonas palustris 45.4 45.4 1 PMID:35624864 -1.18.1.2 5-hydroxy-1,4-naphthoquinone rhodopseudomonas palustris 138.5 138.5 1 PMID:35624864 -1.18.1.2 7-fluoro-tirapazamine rhodopseudomonas palustris 1.2 1.2 1 PMID:35624864 -1.18.1.2 7-hydroxyethyl-tirapazamine rhodopseudomonas palustris 0.46 0.46 1 PMID:35624864 -1.18.1.2 9,10-anthraquinone-2-sulfonate rhodopseudomonas palustris 3.56 3.56 1 PMID:35624864 -1.18.1.2 9,10-phenanthrene quinone rhodopseudomonas palustris 34.6 34.6 1 PMID:35624864 -1.18.1.2 benzylviologen rhodopseudomonas palustris 19.6 19.6 1 PMID:35624864 -1.18.1.2 cb-1954 rhodopseudomonas palustris 0.52 0.52 1 PMID:35624864 -1.18.1.2 dibromothymoquinone spinacia oleracea 25.0 18.8 2 PMID:15271510 -1.18.1.2 duroquinone rhodopseudomonas palustris 4.07 4.07 1 PMID:35624864 -1.18.1.2 fe(cn)63- mycobacterium tuberculosis 63.0 52.5 2 PMID:12071965 -1.18.1.2 fe(edta)- rhodopseudomonas palustris 1.2 1.2 1 PMID:35624864 -1.18.1.2 fe(iii)-edta escherichia coli 3.53 3.2649999999999997 2 PMID:20407804 -1.18.1.2 ferricyanide rhodopseudomonas palustris 394.0 394.0 1 PMID:35624864 -1.18.1.2 n-methylpicramide rhodopseudomonas palustris 5.69 5.69 1 PMID:35624864 -1.18.1.2 nadh anabaena sp. 0.16 0.16 2 PMID:14500716;PMID:19219975 -1.18.1.2 nadh bacillus subtilis 0.4 0.4 1 PMID:15252706 -1.18.1.2 nadh chlorobaculum tepidum 34.7 34.7 1 PMID:33051772 -1.18.1.2 nadh lathyrus oleraceus 7.0 7.0 1 PMID:21306142 -1.18.1.2 nadh pseudomonas putida 19.24 8.695 16 PMID:19114475;PMID:19122206 -1.18.1.2 nadh spinacia oleracea 9.6 9.6 1 PMID:14726209 -1.18.1.2 nadh xanthomonas axonopodis 3.2 3.2 1 PMID:22096528 -1.18.1.2 nadph agarophyton chilense 86.0 71.05 2 PMID:29221464 -1.18.1.2 nadph anabaena sp. 520.0 81.5 5 PMID:12383252;PMID:12709048;PMID:14500716;PMID:19219975 -1.18.1.2 nadph arabidopsis thaliana 3.2 3.2 1 PMID:28833218 -1.18.1.2 nadph bacillus subtilis 1012.0 482.7 4 PMID:15252706;PMID:24529496;PMID:25698107 -1.18.1.2 nadph brucella ovis 14.3 14.3 1 PMID:31394095 -1.18.1.2 nadph chlorobaculum tepidum 213.0 213.0 1 PMID:29119426 -1.18.1.2 nadph cryptosporidium parvum 21.71 0.6 3 PMID:20737579 -1.18.1.2 nadph escherichia coli 520.0 38.2 3 PMID:12709048;PMID:21306142 -1.18.1.2 nadph lathyrus oleraceus 374.3 74.1 3 PMID:17105208;PMID:21306142 -1.18.1.2 nadph leptospira interrogans 258.0 258.0 1 PMID:17958910 -1.18.1.2 nadph plasmodium falciparum 125.0 65.0 5 PMID:19523113;PMID:19736991 -1.18.1.2 nadph pseudomonas putida 37.61 7.335 16 PMID:19114475;PMID:19122206 -1.18.1.2 nadph rhodobacter capsulatus 222.0 20.0 3 PMID:14572660;PMID:24016470 -1.18.1.2 nadph rhodopseudomonas palustris 323.0 323.0 1 PMID:31838096 -1.18.1.2 nadph spinacia oleracea 560.0 500.0 7 PMID:12709048;PMID:14726209;PMID:15271510 -1.18.1.2 nadph toxoplasma gondii 540.0 505.0 2 PMID:15498566;PMID:16533038 -1.18.1.2 nadph trichormus variabilis 517.0 233.0 7 PMID:2506011;PMID:3124746 -1.18.1.2 nadph xanthomonas axonopodis 121.9 121.9 1 PMID:22096528 -1.18.1.2 nadph xanthomonas citri pv. citri 22.6 22.6 1 PMID:29295539 -1.18.1.2 nadph zea mays 76.0 76.0 1 PMID:31665566 -1.18.1.2 nifuroxime rhodopseudomonas palustris 1.3 1.3 1 PMID:35624864 -1.18.1.2 nitrofurantoin rhodopseudomonas palustris 4.4 4.4 1 PMID:35624864 -1.18.1.2 oxidized [2fe-2s]-[rubredoxin] bacillus subtilis 255.0 255.0 1 PMID:33051772 -1.18.1.2 oxidized [2fe-2s]-[rubredoxin] chlorobaculum tepidum 24.8 20.65 2 PMID:33051772 -1.18.1.2 oxidized fdx2 chlamydomonas reinhardtii 248.0 248.0 1 PMID:19586916 -1.18.1.2 oxidized ferredoxin chlamydomonas reinhardtii 252.0 252.0 1 PMID:19586916 -1.18.1.2 oxidized ferredoxin escherichia coli 22.8 11.475 2 PMID:12709048;PMID:21306142 -1.18.1.2 oxidized ferredoxin lathyrus oleraceus 75.0 75.0 1 PMID:21306142 -1.18.1.2 reduced 2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone synechocystis sp. 0.43 0.43 1 PMID:23611948 -1.18.1.2 reduced ferredoxin anabaena sp. 600.0 204.5 6 PMID:12383252;PMID:12709048;PMID:15134648;PMID:15147197 -1.18.1.2 reduced ferredoxin azotobacter vinelandii 1.0 1.0 1 PMID:15134648 -1.18.1.2 reduced ferredoxin chlamydomonas reinhardtii 174.0 174.0 3 PMID:15134648 -1.18.1.2 reduced ferredoxin escherichia coli 0.15 0.15 2 PMID:12234497 -1.18.1.2 reduced ferredoxin lathyrus oleraceus 139.0 139.0 1 PMID:15147197 -1.18.1.2 reduced ferredoxin leptospira interrogans 2.0 2.0 1 PMID:30639162 -1.18.1.2 reduced ferredoxin spinacia oleracea 600.0 600.0 2 PMID:12709048;PMID:15134648 -1.18.1.2 reduced ferredoxin toxoplasma gondii 260.0 260.0 1 PMID:16533038 -1.18.1.2 reduced ferredoxin zea mays 210.0 123.5 4 PMID:31665566 -1.18.1.2 reduced ferredoxin i equisetum arvense 177.0 177.0 1 PMID:12832038 -1.18.1.2 reduced ferredoxin i spinacia oleracea 115.0 82.0 3 PMID:14726209 -1.18.1.2 reduced ferredoxin ii equisetum arvense 32.2 32.2 1 PMID:12832038 -1.18.1.2 reduced ferricyanide synechocystis sp. 0.43 0.43 1 PMID:23611948 -1.18.1.2 reduced flavodoxin anabaena sp. 24.0 23.3 5 PMID:12383252;PMID:15147197;PMID:18177021 -1.18.1.2 reduced flavodoxin escherichia coli 0.004 0.004 1 PMID:15134648 -1.18.1.2 reduced flavodoxin lathyrus oleraceus 30.6 30.6 1 PMID:15147197 -1.18.1.2 reduced flavodoxin rhodobacter capsulatus 0.25 0.25 1 PMID:14572660 -1.18.1.2 reduced flavodoxin triticum aestivum 104.0 104.0 1 PMID:21265508 -1.18.1.2 reduced flavodoxin i escherichia coli 0.0042 0.0042 1 PMID:12234497 -1.18.1.2 reduced flavodoxin ii escherichia coli 0.0039 0.0039 1 PMID:12234497 -1.18.1.2 tirapazamine rhodopseudomonas palustris 0.53 0.53 1 PMID:35624864 -1.18.1.3 ferricyanide mycobacterium sp. 60.2 60.2 1 PMID:16079338 -1.18.1.3 ferricytochrome c mycobacterium sp. 4.5 4.5 1 PMID:16079338 -1.18.1.4 nadh pyrococcus furiosus 498.0 426.0 2 PMID:10464233;PMID:15746356 -1.18.1.4 nadph pyrococcus furiosus 341.0 299.5 2 PMID:10464233;PMID:15746356 -1.18.1.4 oxidized benzyl viologen pyrococcus furiosus 1236.0 1236.0 1 PMID:15746356 -1.18.1.4 oxidized clostridium pasteurianum rubredoxin entamoeba histolytica 13.9 9.95 2 PMID:25725270 -1.18.1.4 oxidized pyrococcus furiosus rubredoxin entamoeba histolytica 69.4 39.5 2 PMID:25725270 -1.18.1.4 oxidized rubredoxin pyrococcus furiosus 15000.0 4665.0 4 PMID:10464233;PMID:15746356 -1.18.1.5 fe(cn)62- pseudomonas putida 671.0 398.5 2 PMID:12011076 -1.18.1.5 fe(cn)63- pseudomonas putida 982.0 982.0 1 PMID:20524621 -1.18.1.5 nadh pseudomonas putida 806.0 806.0 1 PMID:20524621 -1.18.1.5 oxidized 2,6-dichlorophenolindolphenol pseudomonas putida 385.0 385.0 1 PMID:20524621 -1.18.1.5 reduced putidaredoxin pseudomonas putida 264.0 264.0 1 PMID:12011076 -1.18.1.6 ferricyanide mycobacterium tuberculosis 33.7 33.7 1 PMID:12614197 -1.18.1.6 nadh mycobacterium tuberculosis 25.6 25.6 1 PMID:12614197 -1.18.1.6 nadph mycobacterium tuberculosis 50.6 50.6 1 PMID:12614197 -1.18.1.6 oxidized 2,6-dichlorophenolindophenol mycobacterium tuberculosis 0.011 0.011 1 PMID:12614197 -1.18.6.1 flavodoxin hydroquinone azotobacter vinelandii 400.0 400.0 1 PMID:9860849 -1.18.6.1 scn- azotobacter vinelandii 0.3 0.3 1 PMID:9214303 -1.19.1.1 ferricyanide escherichia coli 26.8 26.8 1 PMID:9839946 -1.19.1.1 ferricytochrome c rhodobacter capsulatus 0.25 0.25 1 PMID:14572660 -1.19.1.1 ferricytochrome c2 escherichia coli 2.35 2.35 1 PMID:9839946 -1.19.1.1 nadh escherichia coli 0.55 0.55 1 PMID:11085917 -1.19.1.1 nadph escherichia coli 5.65 5.65 1 PMID:11085917 -1.19.1.1 nadph rhodobacter capsulatus 222.0 20.0 3 PMID:14572660;PMID:24016470 -1.19.1.1 reduced flavodoxin lathyrus oleraceus 30.6 30.6 1 PMID:15147197 -1.19.1.1 reduced flavodoxin nostoc sp. 23.3 23.3 1 PMID:15147197 -1.19.1.1 reduced flavodoxin 1 bacillus cereus 46.3 0.122 3 PMID:30142264 -1.19.1.1 reduced flavodoxin 2 bacillus cereus 152.1 0.7 3 PMID:30142264 -1.19.1.1 reduced flavodoxin i escherichia coli 0.0042 0.0042 1 PMID:12234497 -1.19.1.1 reduced flavodoxin ii escherichia coli 0.0039 0.0039 1 PMID:12234497 -1.19.1.1 reduced flavodoxin-like protein nrdi bacillus cereus 1.67 0.133 3 PMID:30142264 -1.19.6.1 flavodoxin hydroquinone azotobacter vinelandii 400.0 400.0 1 PMID:9860849 -1.2.1.10 acetaldehyde citrobacter sp. s-77 13.0 13.0 1 PMID:26216639 -1.2.1.10 acetaldehyde escherichia coli 15.7 15.7 1 PMID:23237860 -1.2.1.10 acetaldehyde paraburkholderia xenovorans 17.2 17.2 1 PMID:22574886 -1.2.1.10 acetyl-coa citrobacter sp. s-77 0.013 0.013 1 PMID:26216639 -1.2.1.10 butyraldehyde paraburkholderia xenovorans 9.5 9.5 1 PMID:22574886 -1.2.1.10 picolinaldehyde paraburkholderia xenovorans 2.8 2.8 1 PMID:22574886 -1.2.1.10 propionaldehyde paraburkholderia xenovorans 16.3 16.3 1 PMID:22574886 -1.2.1.100 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate mesorhizobium loti 204.0 204.0 1 PMID:19218190 -1.2.1.100 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate pseudomonas sp. ma-1 670.0 670.0 1 PMID:3533936 -1.2.1.102 isopyridoxal arthrobacter sp. cr-7 10.0 10.0 1 PMID:3533936 -1.2.1.103 [amino group carrier protein lysw]-gamma-aminoadipic semialdehyde thermus thermophilus 0.96 0.4855 2 PMID:26966182 -1.2.1.103 nadp+ thermus thermophilus 1.2 1.2 1 PMID:26966182 -1.2.1.103 phosphate thermus thermophilus 1.1 1.1 1 PMID:26966182 -1.2.1.104 n-acetyl-gdllaeietdk(lipoylated)atig-amide mammalia 5.0 5.0 1 PMID:11368334 -1.2.1.104 n-terminal lipoyl domain mammalia 70.0 48.15 2 PMID:11368334 -1.2.1.104 pyruvate homo sapiens 69.9 66.1 3 PMID:16436377;PMID:17042496 -1.2.1.104 thiamine diphosphate escherichia coli 28.89 28.89 1 PMID:11583990 -1.2.1.105 2-oxoadipate homo sapiens 3.6 3.55 2 PMID:28435050 -1.2.1.105 2-oxoglutarate escherichia coli 2.15 2.15 1 PMID:21809826 -1.2.1.105 2-oxoglutarate homo sapiens 18.4 11.299999999999999 2 PMID:28435050 -1.2.1.105 2-oxovalerate escherichia coli 0.076 0.076 1 PMID:21809826 -1.2.1.106 [amino-group carrier protein lysw]-c-terminal-gamma-aminoadipic semialdehyde thermus thermophilus 0.96 0.96 1 PMID:26966182 -1.2.1.106 nadp+ thermus thermophilus 1.2 1.2 1 PMID:26966182 -1.2.1.106 phosphate thermus thermophilus 1.1 1.1 1 PMID:26966182 -1.2.1.107 d-glyceraldehyde 3-phosphate geobacillus stearothermophilus 100.0 100.0 1 * -1.2.1.11 l-4-aspartyl phosphate arabidopsis thaliana 15.6 15.6 1 PMID:11812229 -1.2.1.11 l-aspartate 4-semialdehyde candida albicans 0.12 0.12 1 PMID:20124701 -1.2.1.11 l-aspartate 4-semialdehyde haemophilus influenzae 330.0 330.0 1 PMID:12071715 -1.2.1.11 l-aspartate 4-semialdehyde pseudomonas aeruginosa 160.0 160.0 1 PMID:12071715 -1.2.1.11 l-aspartate 4-semialdehyde vibrio cholerae serotype o1 120.0 89.0 2 PMID:12071715 -1.2.1.11 l-aspartate-4-semialdehyde haemophilus influenzae 330.0 330.0 2 PMID:15272161;PMID:15388927 -1.2.1.11 l-aspartate-semialdehyde streptococcus pneumoniae 2.0 2.0 1 PMID:16895909 -1.2.1.11 nad+ escherichia coli 9.5 9.5 1 PMID:26662025 -1.2.1.11 nadp+ escherichia coli 258.0 258.0 1 PMID:26662025 -1.2.1.11 nadp+ haemophilus influenzae 330.0 330.0 1 PMID:15388927 -1.2.1.11 nadp+ mycobacterium tuberculosis 8.49 8.49 1 PMID:15752328 -1.2.1.11 phosphate haemophilus influenzae 330.0 330.0 1 PMID:15388927 -1.2.1.12 3-phospho-d-glyceroyl phosphate oryza sativa 73.56 73.56 1 PMID:22903596 -1.2.1.12 acetaldehyde neisseria meningitidis 4.03 4.03 1 PMID:17619949 -1.2.1.12 d-glyceraldehyde 3-phosphate fasciola gigantica 1.58 1.58 1 PMID:30706165 -1.2.1.12 d-glyceraldehyde 3-phosphate geobacillus stearothermophilus 70.0 70.0 1 PMID:8823192 -1.2.1.12 d-glyceraldehyde 3-phosphate homo sapiens 234.0 216.5 2 PMID:21269272 -1.2.1.12 d-glyceraldehyde 3-phosphate neisseria meningitidis 24.51 24.51 1 PMID:17619949 -1.2.1.12 d-glyceraldehyde 3-phosphate oryza sativa 122.2 122.2 1 PMID:22903596 -1.2.1.12 d-glyceraldehyde 3-phosphate saccharomyces cerevisiae 29.0 16.35 4 PMID:24456572;PMID:6755173 -1.2.1.12 d-glyceraldehyde 3-phosphate spinacia oleracea 50.0 50.0 1 * -1.2.1.12 d-glyceraldehyde 3-phosphate staphylococcus aureus 70.0 70.0 1 PMID:20620151 -1.2.1.12 d-glyceraldehyde 3-phosphate trypanosoma cruzi 442.0 118.0 3 PMID:17693383 -1.2.1.12 glyceraldehyde neisseria meningitidis 4.35 4.35 1 PMID:17619949 -1.2.1.12 nad+ corynebacterium glutamicum 6.45 6.45 1 PMID:24953302 -1.2.1.12 nad+ fasciola gigantica 1.43 1.43 1 PMID:30706165 -1.2.1.12 nad+ geobacillus stearothermophilus 65.0 65.0 1 PMID:12056886 -1.2.1.12 nad+ homo sapiens 199.0 199.0 1 PMID:21269272 -1.2.1.12 nad+ lactococcus lactis 70.0 70.0 1 PMID:10937934 -1.2.1.12 nad+ oryza sativa japonica group 122.0 122.0 1 PMID:22903596 -1.2.1.12 nad+ saccharolobus solfataricus 20.0 20.0 1 PMID:7663406 -1.2.1.12 nadh oryza sativa japonica group 73.6 73.6 1 PMID:22903596 -1.2.1.13 3-phospho-d-glyceroyl phosphate chlamydomonas reinhardtii 419.0 155.5 4 PMID:12492483 -1.2.1.13 nadh chlamydomonas reinhardtii 104.0 104.0 4 PMID:12492483;PMID:15606760;PMID:21366264 -1.2.1.13 nadh spinacia oleracea 41.0 41.0 1 PMID:15236965 -1.2.1.13 nadph chlamydomonas reinhardtii 430.0 430.0 4 PMID:12492483;PMID:15606760;PMID:21366264 -1.2.1.13 nadph spinacia oleracea 61.0 61.0 1 PMID:15236965 -1.2.1.16 2-oxoglutarate semialdehyde escherichia coli 7.1 7.1 1 PMID:23296511 -1.2.1.16 2-oxoglutarate semialdehyde saccharolobus solfataricus 27.3 24.25 2 PMID:23296511 -1.2.1.16 benzaldehyde stutzerimonas stutzeri 57.0 31.7 2 PMID:17916405 -1.2.1.16 nad+ bacillus subtilis 5.26 5.26 1 PMID:24809290 -1.2.1.16 nad+ crocosphaera subtropica 1.74 1.74 1 PMID:32966327 -1.2.1.16 nad+ escherichia coli 69.0 69.0 1 PMID:23296511 -1.2.1.16 nad+ mycobacterium tuberculosis 2.7 2.7 1 PMID:21303655 -1.2.1.16 nad+ nitrosomonas europaea 0.45 0.45 1 PMID:30690134 -1.2.1.16 nad+ pseudomonas putida 66.0 61.4 4 PMID:18498778 -1.2.1.16 nad+ saccharolobus solfataricus 136.3 136.3 1 PMID:23296511 -1.2.1.16 nad+ salmonella enterica subsp. enterica serovar typhimurium 38.0 38.0 1 PMID:23229889 -1.2.1.16 nad+ streptococcus pyogenes 1.94 1.94 1 PMID:25256219 -1.2.1.16 nad+ stutzerimonas stutzeri 176.0 176.0 1 PMID:17916405 -1.2.1.16 nad+ sulfurisphaera tokodaii 51.2 51.2 1 PMID:23748791 -1.2.1.16 nadp+ bacillus subtilis 9.93 9.93 1 PMID:24809290 -1.2.1.16 nadp+ crocosphaera subtropica 3.9 3.9 1 PMID:32966327 -1.2.1.16 nadp+ mycobacterium tuberculosis 1.3 1.3 1 PMID:21303655 -1.2.1.16 nadp+ nitrosomonas europaea 0.617 0.617 1 PMID:30690134 -1.2.1.16 nadp+ pseudomonas putida 21.1 19.0 4 PMID:18498778 -1.2.1.16 nadp+ saccharolobus solfataricus 16.5 16.5 1 PMID:23296511 -1.2.1.16 nadp+ salmonella enterica subsp. enterica serovar typhimurium 46.0 46.0 1 PMID:23229889 -1.2.1.16 nadp+ streptococcus pyogenes 7.2 7.2 1 PMID:25256219 -1.2.1.16 nadp+ stutzerimonas stutzeri 40.0 40.0 1 PMID:17916405 -1.2.1.16 nadp+ sulfurisphaera tokodaii 27.6 27.6 1 PMID:23748791 -1.2.1.16 succinate semialdehyde bacillus subtilis 7.24 6.425000000000001 2 PMID:24809290 -1.2.1.16 succinate semialdehyde crocosphaera subtropica 3.9 2.82 2 PMID:32966327 -1.2.1.16 succinate semialdehyde mycobacterium tuberculosis 4.7 3.3 2 PMID:21303655 -1.2.1.16 succinate semialdehyde nitrosomonas europaea 0.583 0.5329999999999999 2 PMID:30690134 -1.2.1.16 succinate semialdehyde salmonella enterica subsp. enterica serovar typhimurium 83.0 69.0 2 PMID:23229889 -1.2.1.16 succinate semialdehyde sulfurisphaera tokodaii 30.0 29.7 2 PMID:23748791 -1.2.1.16 succinic semialdehyde escherichia coli 22.6 22.6 1 PMID:23296511 -1.2.1.16 succinic semialdehyde saccharolobus solfataricus 18.4 17.6 2 PMID:23296511 -1.2.1.19 2,2-dimethyl-3-propionylaminopropanal lathyrus oleraceus 14.4 7.905 2 PMID:25344796 -1.2.1.19 2,2-dimethyl-4-aminobutanal lathyrus oleraceus 3.2 3.2 1 PMID:25344796 -1.2.1.19 2,2-dimethyl-4-propionylaminobutanal lathyrus oleraceus 5.8 5.8 1 PMID:25344796 -1.2.1.19 2-methyl-3-butyrylaminopropanal lathyrus oleraceus 12.1 2.215 4 PMID:25344796 -1.2.1.19 2-methyl-3-propionylaminopropanal lathyrus oleraceus 6.49 4.26 2 PMID:25344796 -1.2.1.19 2-methyl-4-propionylaminobutanal lathyrus oleraceus 4.08 3.2 2 PMID:25344796 -1.2.1.19 3-acetaminopropanal lathyrus oleraceus 13.9 8.755 2 PMID:25344796 -1.2.1.19 3-adipylaminopropanal lathyrus oleraceus 8.78 4.904999999999999 2 PMID:25344796 -1.2.1.19 3-aminopropanal lathyrus oleraceus 9.42 6.535 2 PMID:25344796 -1.2.1.19 3-aminopropanal solanum lycopersicum 8.2 7.1 2 PMID:23408433 -1.2.1.19 3-aminopropanal zea mays 11.8 11.1 3 PMID:23408433 -1.2.1.19 3-aminopropionaldehyde lycium ruthenicum 2.38 1.69 2 PMID:29297198 -1.2.1.19 3-butyrylaminopropanal lathyrus oleraceus 8.13 5.2700000000000005 2 PMID:25344796 -1.2.1.19 3-methyl-3-butyrylaminopropanal lathyrus oleraceus 9.54 4.04 4 PMID:25344796 -1.2.1.19 3-propionylaminopropanal lathyrus oleraceus 7.72 5.56 2 PMID:25344796 -1.2.1.19 3-pyridine carboxaldehyde solanum lycopersicum 2.2 2.2 1 PMID:23408433 -1.2.1.19 3-valerylaminopropanal lathyrus oleraceus 11.0 6.51 2 PMID:25344796 -1.2.1.19 4-acetaminobutanal lathyrus oleraceus 2.84 2.665 2 PMID:25344796 -1.2.1.19 4-aminobutanal lathyrus oleraceus 3.1 3.06 2 PMID:25344796 -1.2.1.19 4-aminobutanal solanum lycopersicum 5.2 3.85 2 PMID:23408433 -1.2.1.19 4-aminobutanal zea mays 4.3 1.7 3 PMID:23408433 -1.2.1.19 4-aminobutyraldehyde escherichia coli 7.7 7.7 1 PMID:16023116 -1.2.1.19 4-aminobutyraldehyde lycium ruthenicum 1.32 1.225 2 PMID:29297198 -1.2.1.19 4-butyrylaminobutanal lathyrus oleraceus 1.6 1.495 2 PMID:25344796 -1.2.1.19 4-guanidinobutyraldehyde solanum lycopersicum 4.5 4.2 2 PMID:23408433 -1.2.1.19 4-guanidinobutyraldehyde zea mays 5.0 1.7 3 PMID:23408433 -1.2.1.19 4-propionylaminobutanal lathyrus oleraceus 1.65 1.64 2 PMID:25344796 -1.2.1.19 4-pyridine carboxaldehyde solanum lycopersicum 1.4 1.4 1 PMID:23408433 -1.2.1.19 4-valerylaminobutanal lathyrus oleraceus 1.93 1.49 2 PMID:25344796 -1.2.1.19 betaine aldehyde solanum lycopersicum 1.0 1.0 1 PMID:23408433 -1.2.1.19 betaine aldehyde zea mays 0.6 0.33499999999999996 2 PMID:23408433 -1.2.1.19 butyraldehyde escherichia coli 0.3 0.3 1 PMID:16023116 -1.2.1.19 n,n,n-trimethyl-4-aminobutyraldehyde solanum lycopersicum 3.6 2.8 2 PMID:23408433 -1.2.1.19 n,n,n-trimethyl-4-aminobutyraldehyde zea mays 10.8 5.7 3 PMID:23408433 -1.2.1.22 (s)-lactaldehyde escherichia coli 761.5 761.5 1 PMID:27671251 -1.2.1.22 acetaldehyde escherichia coli 0.6 0.6 1 PMID:16731973 -1.2.1.22 benzaldehyde escherichia coli 0.9 0.9 1 PMID:16731973 -1.2.1.22 d-lactaldehyde methanocaldococcus jannaschii 2.0 2.0 1 PMID:16585745 -1.2.1.22 glycoaldehyde escherichia coli 18.3 18.3 1 PMID:16731973 -1.2.1.22 phenylacetaldehyd escherichia coli 0.5 0.5 1 PMID:16731973 -1.2.1.22 propionaldehyde escherichia coli 1.8 1.8 1 PMID:16731973 -1.2.1.22 propionaldehyde methanocaldococcus jannaschii 3.0 3.0 1 PMID:16585745 -1.2.1.23 methylglyoxal candida albicans 18.17 18.17 1 PMID:24607541 -1.2.1.23 pyruvate candida albicans 170.0 170.0 1 PMID:24607541 -1.2.1.24 2,5-dioxopentanoate saccharolobus solfataricus 7.1 7.1 1 PMID:23296511 -1.2.1.24 alpha-ketoglutaric semialdehyde azospirillum brasilense 51.2 31.75 2 PMID:16835232 -1.2.1.24 glutaraldehyde azospirillum brasilense 12.3 12.3 1 PMID:16835232 -1.2.1.24 nad+ saccharolobus solfataricus 69.0 69.0 1 PMID:23296511 -1.2.1.24 succinate semialdehyde azospirillum brasilense 31.7 31.7 1 PMID:16835232 -1.2.1.24 succinate semialdehyde saccharolobus solfataricus 22.6 22.6 1 PMID:23296511 -1.2.1.26 2,5-dioxopentanoate saccharolobus solfataricus 8.6 8.6 1 PMID:16849334 -1.2.1.26 3-hydroxypropionaldehyde azospirillum brasilense 15.0 15.0 1 PMID:29214999 -1.2.1.26 acetaldehyde acinetobacter baylyi 0.41 0.41 1 PMID:18364348 -1.2.1.26 alpha-ketoglutaric semialdehyde azospirillum brasilense 53.9 22.15 4 PMID:17202142 -1.2.1.26 alpha-ketoglutaric semialdehyde bacillus subtilis 2.75 1.935 2 PMID:17202142 -1.2.1.26 alpha-ketoglutaric semialdehyde pseudomonas putida 197.0 197.0 1 PMID:18364348 -1.2.1.26 butylaldehyde bacillus subtilis 1.35 1.35 1 PMID:17202142 -1.2.1.26 dl-glyceraldehyde saccharolobus solfataricus 4.8 4.8 1 PMID:16849334 -1.2.1.26 glutaraldehyde acinetobacter baylyi 4.13 2.39 2 PMID:18364348 -1.2.1.26 glycolaldehyde saccharolobus solfataricus 5.3 5.3 1 PMID:16849334 -1.2.1.26 heptaldehyde bacillus subtilis 0.87 0.87 1 PMID:17202142 -1.2.1.26 hexylaldehyde bacillus subtilis 1.47 1.47 1 PMID:17202142 -1.2.1.26 nad+ acinetobacter baylyi 57.0 57.0 1 PMID:18364348 -1.2.1.26 nad+ azospirillum brasilense 52.3 26.1 4 PMID:17202142;PMID:29214999 -1.2.1.26 nad+ bacillus subtilis 0.74 0.74 1 PMID:17202142 -1.2.1.26 nadp+ acinetobacter baylyi 55.0 55.0 1 PMID:18364348 -1.2.1.26 nadp+ azospirillum brasilense 15.3 10.03 4 PMID:17202142;PMID:29214999 -1.2.1.26 nadp+ bacillus subtilis 1.08 1.08 1 PMID:17202142 -1.2.1.26 octylaldehyde bacillus subtilis 0.97 0.97 1 PMID:17202142 -1.2.1.26 propanal acinetobacter baylyi 2.07 1.325 2 PMID:18364348 -1.2.1.26 propionaldehyde bacillus subtilis 1.29 1.29 1 PMID:17202142 -1.2.1.26 succinate semialdehyde acinetobacter baylyi 0.06 0.055 2 PMID:18364348 -1.2.1.26 valeraldehyde bacillus subtilis 2.1 2.1 1 PMID:17202142 -1.2.1.27 2-methyl-3-oxopropanoate bacillus subtilis 1.1 1.1 1 PMID:16332250 -1.2.1.27 2-methyl-3-oxopropanoate saccharolobus solfataricus 0.003 0.003 1 PMID:23296511 -1.2.1.27 coa bacillus subtilis 12.6 12.6 1 PMID:21515690 -1.2.1.27 malonate semialdehyde saccharolobus solfataricus 0.02 0.02 2 PMID:23296511 -1.2.1.27 methylmalonate semialdehyde saccharolobus solfataricus 0.003 0.003 1 PMID:23296511 -1.2.1.27 nad+ bacillus subtilis 2.2 0.3 8 PMID:21515690;PMID:22782904 -1.2.1.27 propionaldehyde saccharolobus solfataricus 0.03 0.03 2 PMID:23296511 -1.2.1.28 2-hydroxybenzaldehyde acinetobacter calcoaceticus 41.0 41.0 1 PMID:3060114 -1.2.1.28 2-hydroxybenzaldehyde pseudomonas putida 33.0 33.0 2 PMID:21448720 -1.2.1.28 2-methylbenzaldehyde pseudomonas putida 39.0 39.0 2 PMID:21448720 -1.2.1.28 2-naphthaldehyde pseudomonas putida 56.0 56.0 2 PMID:21448720 -1.2.1.28 3-chlorobenzaldehyde pseudomonas putida 16.0 16.0 2 PMID:21448720 -1.2.1.28 3-fluorobenzaldehyde acinetobacter calcoaceticus 41.0 41.0 1 PMID:3060114 -1.2.1.28 3-hydroxybenzaldehyde acinetobacter calcoaceticus 29.0 29.0 1 PMID:3060114 -1.2.1.28 3-hydroxybenzaldehyde pseudomonas putida 24.0 24.0 2 PMID:21448720 -1.2.1.28 3-methoxybenzaldehyde acinetobacter calcoaceticus 33.0 33.0 1 PMID:3060114 -1.2.1.28 3-methoxybenzaldehyde pseudomonas putida 885.0 885.0 2 PMID:21448720 -1.2.1.28 3-methylbenzaldehyde pseudomonas putida 23.0 23.0 2 PMID:21448720 -1.2.1.28 4-chlorobenzaldehyde pseudomonas putida 135.0 67.0 3 PMID:21448720;PMID:28338942 -1.2.1.28 4-fluorobenzaldehyde acinetobacter calcoaceticus 64.0 64.0 1 PMID:3060114 -1.2.1.28 4-hydroxybenzaldehyde acinetobacter calcoaceticus 20.0 20.0 1 PMID:3060114 -1.2.1.28 4-methoxybenzaldehyde acinetobacter calcoaceticus 49.0 49.0 1 PMID:3060114 -1.2.1.28 4-methoxybenzaldehyde pseudomonas putida 116.0 101.0 3 PMID:21448720;PMID:28338942 -1.2.1.28 4-methylbenzaldehyde pseudomonas putida 120.0 120.0 2 PMID:21448720 -1.2.1.28 4-nitrobenzaldehyde pseudomonas putida 95.0 95.0 1 PMID:28338942 -1.2.1.28 acetaldehyde antirrhinum majus 2.08 2.08 1 PMID:19292760 -1.2.1.28 benzaldehyde acinetobacter calcoaceticus 72.0 72.0 1 PMID:3060114 -1.2.1.28 benzaldehyde antirrhinum majus 0.31 0.31 1 PMID:19292760 -1.2.1.28 benzaldehyde pseudomonas putida 156.0 14.0 3 PMID:21448720;PMID:28338942 -1.2.1.28 cinnamaldehyde acinetobacter calcoaceticus 26.0 26.0 1 PMID:3060114 -1.2.1.28 furan-2-carboxaldehyde acinetobacter calcoaceticus 46.0 46.0 1 PMID:3060114 -1.2.1.28 hexan-1-al acinetobacter calcoaceticus 29.0 29.0 1 PMID:3060114 -1.2.1.28 octan-1-al acinetobacter calcoaceticus 26.0 26.0 1 PMID:3060114 -1.2.1.28 perillaldehyde acinetobacter calcoaceticus 17.0 17.0 1 PMID:3060114 -1.2.1.28 phenylacetaldehyde antirrhinum majus 0.23 0.23 1 PMID:19292760 -1.2.1.28 pyridine-3-carboxaldehyde acinetobacter calcoaceticus 68.0 68.0 1 PMID:3060114 -1.2.1.28 pyridine-4-carboxaldehyde acinetobacter calcoaceticus 66.0 66.0 1 PMID:3060114 -1.2.1.28 thiophen-2-carboxyaldehyde acinetobacter calcoaceticus 52.0 52.0 1 PMID:3060114 -1.2.1.3 (r)-trans-4-hydroxy-2-nonenal rattus norvegicus 0.039 0.039 1 PMID:17480102 -1.2.1.3 (s)-trans-4-hydroxy-2-nonenal rattus norvegicus 0.04 0.04 1 PMID:17480102 -1.2.1.3 2,4-dinitrobenzaldehyde homo sapiens 0.667 0.667 1 PMID:8605195 -1.2.1.3 2-naphthaldehyde homo sapiens 4.0 4.0 1 PMID:8605195 -1.2.1.3 2-quinolinone-4-carboxaldehyde homo sapiens 1.57 1.57 1 PMID:8605195 -1.2.1.3 3,4-dimethoxybenzaldehyde homo sapiens 1.42 1.42 1 PMID:8605195 -1.2.1.3 3-hydroxypropionaldehyde escherichia coli 28.54 16.725 2 PMID:18668238 -1.2.1.3 3-hydroxypropionic acid escherichia coli 0.26 0.26 1 PMID:18668238 -1.2.1.3 3-oxopropyl phosphonate sinorhizobium meliloti 1.5 1.5 1 PMID:24706911 -1.2.1.3 3-pyridinecarboxaldehyde homo sapiens 27.7 27.7 1 PMID:8605195 -1.2.1.3 4-methoxy-1-naphthaldehyde homo sapiens 4.42 4.42 1 PMID:8605195 -1.2.1.3 4-nitrophenyl acetate bos taurus 0.26 0.26 1 PMID:6651766 -1.2.1.3 5-(dimethylamino)-2-naphthaldehyde homo sapiens 2.67 2.67 1 PMID:8605195 -1.2.1.3 5-bromo-1-naphthaldehyde homo sapiens 0.25 0.20400000000000001 2 PMID:8605195 -1.2.1.3 5-nitro-1-naphthaldehyde homo sapiens 0.833 0.6915 2 PMID:8605195 -1.2.1.3 6,7-dimethoxycoumarin-3-carboxaldehyde homo sapiens 0.983 0.983 1 PMID:8605195 -1.2.1.3 6-(dimethylamino)-2-naphthaldehyde homo sapiens 0.617 0.617 1 PMID:8605195 -1.2.1.3 6-methoxy-2-quinolinone-4-carboxaldehyde homo sapiens 0.983 0.983 1 PMID:8605195 -1.2.1.3 7-(dimethylamino)-2-quinolinone-4-carboxaldehyde homo sapiens 2.17 2.17 1 PMID:8605195 -1.2.1.3 7-(dimethylamino)-coumarin-3-carboxaldehyde homo sapiens 1.3 1.3 1 PMID:8605195 -1.2.1.3 7-(dimethylamino)coumarin-4-carboxaldehyde homo sapiens 7.9 7.9 1 PMID:8605195 -1.2.1.3 7-acetoxycoumarin-3-carboxaldehyde homo sapiens 1.08 1.08 1 PMID:8605195 -1.2.1.3 7-hydroxycoumarin-3-carboxaldehyde homo sapiens 8.33 8.33 1 PMID:8605195 -1.2.1.3 7-methoxy-2-quinolinone-4-carboxaldehyde homo sapiens 5.33 5.33 1 PMID:8605195 -1.2.1.3 7-methoxycoumarin-3-carboxaldehyde homo sapiens 3.17 3.17 1 PMID:8605195 -1.2.1.3 acetaldehyde acetivibrio thermocellus 240.0 240.0 1 PMID:26013492 -1.2.1.3 acetaldehyde bos taurus 1.86 1.86 1 PMID:6651766 -1.2.1.3 acetaldehyde escherichia coli 11.03 11.03 1 PMID:18668238 -1.2.1.3 acetaldehyde homo sapiens 19.7 16.45 2 PMID:8155713;PMID:8605195 -1.2.1.3 acetaldehyde lachnoclostridium phytofermentans 1.62 1.62 1 PMID:26899032 -1.2.1.3 acetaldehyde rattus norvegicus 3.5 1.88 2 PMID:17480102 -1.2.1.3 acetaldehyde sulfurisphaera tokodaii 1.14 1.14 1 PMID:23224332 -1.2.1.3 alpha-aminoadipate semialdehyde homo sapiens 0.3 0.3 1 PMID:29045138 -1.2.1.3 alpha-phenylpropanal homo sapiens 15.2 15.2 1 PMID:8605195 -1.2.1.3 benzaldehyde escherichia coli 17.37 17.37 1 PMID:18668238 -1.2.1.3 benzaldehyde homo sapiens 5.83 5.83 1 PMID:8605195 -1.2.1.3 benzaldehyde pseudomonas putida 0.137 0.08975000000000001 2 PMID:12670968 -1.2.1.3 butyraldehyde escherichia coli 26.95 26.95 1 PMID:18668238 -1.2.1.3 butyraldehyde lachnoclostridium phytofermentans 3.44 3.44 1 PMID:26899032 -1.2.1.3 decanal homo sapiens 11.7 7.765 2 PMID:8605195 -1.2.1.3 dl-glyceraldehyde sulfurisphaera tokodaii 0.92 0.92 1 PMID:23224332 -1.2.1.3 dl-glyceraldehyde 3-phosphate sulfurisphaera tokodaii 0.83 0.83 1 PMID:23224332 -1.2.1.3 fluorene-2-carboxaldehyde homo sapiens 6.0 4.415 2 PMID:8605195 -1.2.1.3 formaldehyde homo sapiens 67.5 67.5 1 PMID:8605195 -1.2.1.3 glutathione-4-oxonon-2-enal homo sapiens 0.04 0.04 1 PMID:16411662 -1.2.1.3 glyceraldehyde bos taurus 1.29 1.29 1 PMID:6651766 -1.2.1.3 glyceraldehyde 3-phosphate bos taurus 0.28 0.28 1 PMID:6651766 -1.2.1.3 glyceraldehyde 3-phosphate sinorhizobium meliloti 0.098 0.098 1 PMID:24706911 -1.2.1.3 glycolaldehyde bos taurus 1.2 1.2 1 PMID:6651766 -1.2.1.3 heptanal homo sapiens 22.7 13.515 2 PMID:8605195 -1.2.1.3 hexanal arabidopsis thaliana 11.2 11.2 1 PMID:24463048 -1.2.1.3 hexanal homo sapiens 28.5 16.335 2 PMID:8605195 -1.2.1.3 hexanal loktanella sp. 3.3 3.3 1 PMID:30529746 -1.2.1.3 hexanaldehyde lachnoclostridium phytofermentans 5.61 5.61 1 PMID:26899032 -1.2.1.3 hydrocinnamaldehyde homo sapiens 12.3 12.3 1 PMID:8605195 -1.2.1.3 indole-3-acetaldehyde homo sapiens 11.3 10.315000000000001 2 PMID:8605195 -1.2.1.3 isovaleraldehyde escherichia coli 27.31 27.31 1 PMID:18668238 -1.2.1.3 m-hydroxybenzaldehyde homo sapiens 1.0 1.0 1 PMID:8605195 -1.2.1.3 m-methoxybenzaldehyde homo sapiens 5.83 5.83 1 PMID:8605195 -1.2.1.3 m-methylbenzaldehyde homo sapiens 4.5 4.5 1 PMID:8605195 -1.2.1.3 malondialdehyde bos taurus 1.19 1.19 1 PMID:6651766 -1.2.1.3 nad+ arabidopsis thaliana 17.2 17.2 1 PMID:24463048 -1.2.1.3 nad+ homo sapiens 3.5 3.05 3 PMID:10819999;PMID:27521998 -1.2.1.3 nad+ sulfurisphaera tokodaii 2.05 1.325 2 PMID:23224332 -1.2.1.3 nadh acetivibrio thermocellus 240.0 240.0 1 PMID:26013492 -1.2.1.3 nadp+ sulfurisphaera tokodaii 3.71 2.67 2 PMID:23224332 -1.2.1.3 nonanal arabidopsis thaliana 17.9 17.9 1 PMID:24463048 -1.2.1.3 o-methoxybenzaldehyde homo sapiens 0.367 0.367 1 PMID:8605195 -1.2.1.3 o-methylbenzaldehyde homo sapiens 2.75 2.75 1 PMID:8605195 -1.2.1.3 o-nitrobenzaldehyde homo sapiens 1.23 1.23 1 PMID:8605195 -1.2.1.3 octanal homo sapiens 15.0 9.585 2 PMID:8605195 -1.2.1.3 p-(dimethylamino)-benzaldehyde homo sapiens 2.33 2.33 1 PMID:8605195 -1.2.1.3 p-(dimethylamino)benzaldehyde homo sapiens 2.13 2.13 1 PMID:8605195 -1.2.1.3 p-(dimethylamino)cinnamaldehyde homo sapiens 8.17 4.835 2 PMID:8605195 -1.2.1.3 p-methoxybenzaldehyde homo sapiens 2.5 2.5 1 PMID:8605195 -1.2.1.3 p-methylbenzaldehyde homo sapiens 3.0 3.0 1 PMID:8605195 -1.2.1.3 p-nitrobenzaldehyde bos taurus 0.23 0.23 1 PMID:6651766 -1.2.1.3 p-nitrobenzaldehyde homo sapiens 7.17 7.17 1 PMID:8605195 -1.2.1.3 p-nitrocinnamaldehyde homo sapiens 0.45 0.45 1 PMID:8605195 -1.2.1.3 pentanal homo sapiens 22.8 15.485 2 PMID:8605195 -1.2.1.3 pentanaldehyde lachnoclostridium phytofermentans 5.44 5.44 1 PMID:26899032 -1.2.1.3 phenanthrene-9-carboxaldehyde homo sapiens 0.3 0.3 1 PMID:8605195 -1.2.1.3 phenylacetaldehyde bos taurus 1.39 1.39 1 PMID:6651766 -1.2.1.3 phenylacetaldehyde homo sapiens 50.0 40.0 2 PMID:8605195 -1.2.1.3 phosphonoacetaldehyde sinorhizobium meliloti 2.2 2.2 2 PMID:24361046;PMID:24706911 -1.2.1.3 propanal bos taurus 1.85 1.85 1 PMID:6651766 -1.2.1.3 propanal homo sapiens 19.7 1.9 9 PMID:15924421;PMID:16878979;PMID:27521998;PMID:8605195 -1.2.1.3 propionaldehyde escherichia coli 24.35 24.35 1 PMID:18668238 -1.2.1.3 propionaldehyde lachnoclostridium phytofermentans 3.45 3.45 1 PMID:26899032 -1.2.1.3 quinoline-3-carboxaldehyde homo sapiens 11.2 11.2 1 PMID:8605195 -1.2.1.3 quinoline-4-carboxaldehyde homo sapiens 4.67 4.67 1 PMID:8605195 -1.2.1.3 succinic semialdehyde bos taurus 0.76 0.76 1 PMID:6651766 -1.2.1.3 trans-2-hexenal arabidopsis thaliana 2.2 2.2 1 PMID:24463048 -1.2.1.3 trans-2-nonenal arabidopsis thaliana 2.7 2.7 1 PMID:24463048 -1.2.1.3 trans-cinnamaldehyde homo sapiens 7.83 5.165 2 PMID:8605195 -1.2.1.3 valeraldehyde escherichia coli 26.24 26.24 1 PMID:18668238 -1.2.1.30 (e)-3-phenylprop-2-enoate mycolicibacterium phlei 1.12 1.12 1 PMID:28450969 -1.2.1.30 (e)-3-phenylprop-2-enoate mycolicibacterium smegmatis 1.97 1.97 1 PMID:28450969 -1.2.1.30 (e)-3-phenylprop-2-enoate nocardia iowensis 0.128 0.128 1 PMID:28450969 -1.2.1.30 (e)-3-phenylprop-2-enoate nocardia otitidiscaviarum 1.75 1.75 1 PMID:28450969 -1.2.1.30 (e)-3-phenylprop-2-enoate tsukamurella paurometabola 0.63 0.63 1 PMID:28450969 -1.2.1.30 2-methoxybenzoate tsukamurella paurometabola 0.317 0.317 1 PMID:28450969 -1.2.1.30 3-methoxybenzoate mycolicibacterium phlei 1.73 1.73 1 PMID:28450969 -1.2.1.30 3-methoxybenzoate mycolicibacterium smegmatis 0.3 0.3 1 PMID:28450969 -1.2.1.30 3-methoxybenzoate nocardia iowensis 1.55 1.55 1 PMID:28450969 -1.2.1.30 3-methoxybenzoate nocardia otitidiscaviarum 2.27 2.27 1 PMID:28450969 -1.2.1.30 3-methoxybenzoate tsukamurella paurometabola 3.1 3.1 1 PMID:28450969 -1.2.1.30 3-nitrobenzoate mycolicibacterium phlei 0.062 0.062 1 PMID:28450969 -1.2.1.30 3-nitrobenzoate mycolicibacterium smegmatis 0.67 0.67 1 PMID:28450969 -1.2.1.30 3-nitrobenzoate nocardia iowensis 0.3 0.3 1 PMID:28450969 -1.2.1.30 3-nitrobenzoate nocardia otitidiscaviarum 0.983 0.983 1 PMID:28450969 -1.2.1.30 3-nitrobenzoate tsukamurella paurometabola 0.55 0.55 1 PMID:28450969 -1.2.1.30 3-oxo-3-phenylpropanoate mycolicibacterium phlei 0.3 0.3 1 PMID:28450969 -1.2.1.30 3-oxo-3-phenylpropanoate mycolicibacterium smegmatis 1.25 1.25 1 PMID:28450969 -1.2.1.30 3-oxo-3-phenylpropanoate nocardia iowensis 0.618 0.618 1 PMID:28450969 -1.2.1.30 3-oxo-3-phenylpropanoate nocardia otitidiscaviarum 1.05 1.05 1 PMID:28450969 -1.2.1.30 3-oxo-3-phenylpropanoate tsukamurella paurometabola 1.42 1.42 1 PMID:28450969 -1.2.1.30 3-phenylprop-2-ynoate nocardia iowensis 0.117 0.117 1 PMID:28450969 -1.2.1.30 3-phenylprop-2-ynoate tsukamurella paurometabola 0.1 0.1 1 PMID:28450969 -1.2.1.30 3-phenylpropionate mycolicibacterium phlei 0.358 0.358 1 PMID:28450969 -1.2.1.30 3-phenylpropionate mycolicibacterium smegmatis 3.07 3.07 1 PMID:28450969 -1.2.1.30 3-phenylpropionate nocardia iowensis 1.43 1.43 1 PMID:28450969 -1.2.1.30 3-phenylpropionate nocardia otitidiscaviarum 2.33 2.33 1 PMID:28450969 -1.2.1.30 3-phenylpropionate tsukamurella paurometabola 2.63 2.63 1 PMID:28450969 -1.2.1.30 4-methoxybenzoate mycolicibacterium phlei 2.2 2.2 1 PMID:28450969 -1.2.1.30 4-methoxybenzoate mycolicibacterium smegmatis 2.98 2.98 1 PMID:28450969 -1.2.1.30 4-methoxybenzoate nocardia iowensis 0.82 0.82 1 PMID:28450969 -1.2.1.30 4-methoxybenzoate nocardia otitidiscaviarum 2.3 2.3 1 PMID:28450969 -1.2.1.30 4-methoxybenzoate tsukamurella paurometabola 2.17 2.17 1 PMID:28450969 -1.2.1.30 4-methylbenzoate mycolicibacterium phlei 2.03 2.03 1 PMID:28450969 -1.2.1.30 4-methylbenzoate mycolicibacterium smegmatis 2.57 2.57 1 PMID:28450969 -1.2.1.30 4-methylbenzoate nocardia iowensis 1.57 1.57 1 PMID:28450969 -1.2.1.30 4-methylbenzoate nocardia otitidiscaviarum 2.3 2.3 1 PMID:28450969 -1.2.1.30 4-methylbenzoate tsukamurella paurometabola 2.53 2.53 1 PMID:28450969 -1.2.1.30 4-nitrobenzoate tsukamurella paurometabola 2.17 2.17 1 PMID:28450969 -1.2.1.30 benzoate mycolicibacterium phlei 2.33 2.33 1 PMID:28450969 -1.2.1.30 benzoate mycolicibacterium smegmatis 3.28 3.28 1 PMID:28450969 -1.2.1.30 benzoate nocardia iowensis 1.63 1.63 1 PMID:28450969 -1.2.1.30 benzoate nocardia otitidiscaviarum 3.05 3.05 1 PMID:28450969 -1.2.1.30 benzoate tsukamurella paurometabola 2.37 2.37 1 PMID:28450969 -1.2.1.30 butanoate mycolicibacterium smegmatis 2.15 2.15 1 PMID:28450969 -1.2.1.30 butanoate nocardia iowensis 4.33 4.33 1 PMID:28450969 -1.2.1.30 butanoate nocardia otitidiscaviarum 2.83 2.83 1 PMID:28450969 -1.2.1.30 butanoate tsukamurella paurometabola 1.37 1.37 1 PMID:28450969 -1.2.1.30 dodecanoate mycolicibacterium phlei 0.92 0.92 1 PMID:28450969 -1.2.1.30 dodecanoate mycolicibacterium smegmatis 2.18 2.18 1 PMID:28450969 -1.2.1.30 dodecanoate nocardia iowensis 2.62 2.62 1 PMID:28450969 -1.2.1.30 dodecanoate nocardia otitidiscaviarum 1.65 1.65 1 PMID:28450969 -1.2.1.30 dodecanoate tsukamurella paurometabola 2.62 2.62 1 PMID:28450969 -1.2.1.30 furan-2-carboxylate mycolicibacterium smegmatis 0.83 0.83 1 PMID:28450969 -1.2.1.30 furan-2-carboxylate tsukamurella paurometabola 0.32 0.32 1 PMID:28450969 -1.2.1.30 octadecanoate mycolicibacterium phlei 0.062 0.062 1 PMID:28450969 -1.2.1.30 octadecanoate mycolicibacterium smegmatis 0.77 0.77 1 PMID:28450969 -1.2.1.30 octadecanoate nocardia iowensis 1.13 1.13 1 PMID:28450969 -1.2.1.30 octadecanoate nocardia otitidiscaviarum 0.183 0.183 1 PMID:28450969 -1.2.1.30 octadecanoate tsukamurella paurometabola 0.25 0.25 1 PMID:28450969 -1.2.1.30 octanoate mycolicibacterium phlei 0.97 0.97 1 PMID:28450969 -1.2.1.30 octanoate mycolicibacterium smegmatis 4.93 4.93 1 PMID:28450969 -1.2.1.30 octanoate nocardia iowensis 3.88 3.88 1 PMID:28450969 -1.2.1.30 octanoate nocardia otitidiscaviarum 2.35 2.35 1 PMID:28450969 -1.2.1.30 octanoate tsukamurella paurometabola 3.65 3.65 1 PMID:28450969 -1.2.1.30 pyridine-2-carboxylate nocardia otitidiscaviarum 1.27 1.27 1 PMID:28450969 -1.2.1.30 pyridine-2-carboxylate tsukamurella paurometabola 0.38 0.38 1 PMID:28450969 -1.2.1.30 thiophene-2-carboxylate mycolicibacterium phlei 0.83 0.83 1 PMID:28450969 -1.2.1.30 thiophene-2-carboxylate mycolicibacterium smegmatis 2.05 2.05 1 PMID:28450969 -1.2.1.30 thiophene-2-carboxylate nocardia iowensis 1.01 1.01 1 PMID:28450969 -1.2.1.30 thiophene-2-carboxylate nocardia otitidiscaviarum 2.25 2.25 1 PMID:28450969 -1.2.1.30 thiophene-2-carboxylate tsukamurella paurometabola 1.37 1.37 1 PMID:28450969 -1.2.1.30 trans-2-phenylcyclopropane-1-carboxylate mycolicibacterium phlei 0.33 0.33 1 PMID:28450969 -1.2.1.30 trans-2-phenylcyclopropane-1-carboxylate mycolicibacterium smegmatis 0.37 0.37 1 PMID:28450969 -1.2.1.30 trans-2-phenylcyclopropane-1-carboxylate nocardia iowensis 0.18 0.18 1 PMID:28450969 -1.2.1.30 trans-2-phenylcyclopropane-1-carboxylate nocardia otitidiscaviarum 0.8 0.8 1 PMID:28450969 -1.2.1.30 trans-2-phenylcyclopropane-1-carboxylate tsukamurella paurometabola 0.717 0.717 1 PMID:28450969 -1.2.1.31 alpha-aminoadipate semialdehyde saccharomyces cerevisiae 11.2 11.2 1 PMID:10320345 -1.2.1.31 l-2-aminoadipate penicillium chrysogenum 66.0 66.0 1 PMID:12509419 -1.2.1.32 2-aminomuconate 6-semialdehyde homo sapiens 0.42 0.42 1 PMID:29703752 -1.2.1.32 2-hydroxy-5-methyl-muconic-6-semialdehyde burkholderia cepacia 99300.0 99300.0 1 PMID:15202565 -1.2.1.32 2-hydroxymuconate-6-semialdehyde burkholderia cepacia 21900.0 21900.0 1 PMID:15202565 -1.2.1.32 5-chloro-2-hydroxymuconic-6-semialdehyde burkholderia cepacia 2300.0 2300.0 1 PMID:15202565 -1.2.1.36 2,4-decadienal rattus norvegicus 0.15 0.15 1 PMID:23220587 -1.2.1.36 all-trans-retinal homo sapiens 0.07 0.07 1 PMID:23220587 -1.2.1.36 all-trans-retinal rattus norvegicus 0.1 0.1 1 PMID:23220587 -1.2.1.36 benzaldehyde mus musculus 0.2 0.2 1 PMID:16241904 -1.2.1.36 beta-apo-12'-carotenal homo sapiens 0.142 0.08199999999999999 2 * -1.2.1.36 beta-apo-14'-carotenal homo sapiens 0.078 0.065 2 * -1.2.1.36 citral rattus norvegicus 0.1 0.1 1 PMID:23220587 -1.2.1.36 decanal homo sapiens 1.0 1.0 1 PMID:23220587 -1.2.1.36 decanal mus musculus 0.4 0.4 1 PMID:16241904 -1.2.1.36 decanal rattus norvegicus 2.2 2.2 1 PMID:23220587 -1.2.1.36 hexanal mus musculus 0.3 0.3 1 PMID:16241904 -1.2.1.36 hexanal rattus norvegicus 2.0 2.0 1 PMID:23220587 -1.2.1.36 nad+ mus musculus 3.3 3.3 1 PMID:16241904 -1.2.1.36 octanal mus musculus 4.8 4.8 1 PMID:16241904 -1.2.1.36 retinal mus musculus 3.9 3.9 1 PMID:16241904 -1.2.1.39 acetaldehyde escherichia coli 14.5 14.5 1 PMID:16731973 -1.2.1.39 benzaldehyde escherichia coli 0.16 0.16 1 PMID:16731973 -1.2.1.39 heptanal escherichia coli 26.7 26.7 1 PMID:16731973 -1.2.1.39 hexanal escherichia coli 21.8 21.8 1 PMID:16731973 -1.2.1.39 nad+ aromatoleum aromaticum 53.0 53.0 1 PMID:24214948 -1.2.1.39 nad+ escherichia coli 20.17 11.835 2 PMID:16731973 -1.2.1.39 nadp+ aromatoleum aromaticum 63.0 63.0 1 PMID:24214948 -1.2.1.39 nadp+ escherichia coli 9.0 9.0 1 PMID:16731973 -1.2.1.39 phenylacetaldehyde escherichia coli 96.8 96.8 1 PMID:16731973 -1.2.1.39 propionaldehyde escherichia coli 20.8 20.8 1 PMID:16731973 -1.2.1.4 acetaldehyde paenarthrobacter nicotinovorans 0.75 0.75 1 PMID:23063486 -1.2.1.4 benzaldehyde paenarthrobacter nicotinovorans 4.52 4.52 1 PMID:23063486 -1.2.1.4 butyraldehyde paenarthrobacter nicotinovorans 0.65 0.65 1 PMID:23063486 -1.2.1.4 formaldehyde paenarthrobacter nicotinovorans 0.33 0.33 1 PMID:23063486 -1.2.1.4 glutaraldehyde paenarthrobacter nicotinovorans 3.92 3.92 1 PMID:23063486 -1.2.1.4 glyceraldehyde paenarthrobacter nicotinovorans 1.35 1.35 1 PMID:23063486 -1.2.1.4 glyceraldehyde pyrobaculum ferrireducens 1.2 1.2 1 PMID:27956891 -1.2.1.4 isobutyraldehyde pyrobaculum ferrireducens 4.1 4.1 1 PMID:27956891 -1.2.1.4 nad+ paenarthrobacter nicotinovorans 3.1 3.1 1 PMID:23063486 -1.2.1.4 nadp+ paenarthrobacter nicotinovorans 1.02 1.02 1 PMID:23063486 -1.2.1.4 propionaldehyde paenarthrobacter nicotinovorans 1.2 1.2 1 PMID:23063486 -1.2.1.4 propionaldehyde pyrobaculum ferrireducens 2.9 2.9 1 PMID:27956891 -1.2.1.42 acetyl-coa porphyromonas gingivalis 0.08 0.08 1 * -1.2.1.42 butanoyl-coa porphyromonas gingivalis 0.19 0.19 1 * -1.2.1.44 4-coumaroyl-coa fragaria x ananassa 2.65e-05 2.65e-05 1 PMID:25346738 -1.2.1.44 4-coumaroyl-coa oryza sativa japonica group 0.353 0.129 3 PMID:29312373 -1.2.1.44 4-coumaroyl-coa panicum virgatum 0.32 0.254 2 PMID:19761442 -1.2.1.44 4-coumaroyl-coa petunia x hybrida 1.2 1.2 1 PMID:25217505 -1.2.1.44 4-coumaroyl-coa populus tomentosa 0.0183 0.0183 1 PMID:27580618 -1.2.1.44 4-coumaroyl-coa selaginella moellendorffii 0.324 0.278 2 PMID:28321576 -1.2.1.44 4-coumaroyl-coa sorghum bicolor 0.05 0.05 1 PMID:27956488 -1.2.1.44 5-hydroxyferuloyl-coa populus tremuloides 4.9 4.9 1 PMID:15870094 -1.2.1.44 caffeoyl-coa arabidopsis thaliana 0.0363 0.0254 2 PMID:11430991 -1.2.1.44 caffeoyl-coa fragaria x ananassa 2.93e-05 2.93e-05 1 PMID:25346738 -1.2.1.44 caffeoyl-coa leucaena leucocephala 113.0 113.0 1 PMID:23541561 -1.2.1.44 caffeoyl-coa panicum virgatum 0.23 0.196 2 PMID:19761442 -1.2.1.44 caffeoyl-coa populus tomentosa 0.0362 0.0362 1 PMID:27580618 -1.2.1.44 caffeoyl-coa populus tremuloides 0.7 0.7 1 PMID:15870094 -1.2.1.44 caffeoyl-coa selaginella moellendorffii 0.559 0.4425 2 PMID:28321576 -1.2.1.44 caffeoyl-coa solanum lycopersicum 0.33 0.33 1 PMID:16551686 -1.2.1.44 caffeoyl-coa sorghum bicolor 0.01 0.01 1 PMID:27956488 -1.2.1.44 coniferaldehyde leucaena leucocephala 236.0 165.0 2 PMID:23541561 -1.2.1.44 coumaroyl-coa leucaena leucocephala 105.0 105.0 1 PMID:23541561 -1.2.1.44 coumaroyl-coa solanum lycopersicum 0.43 0.43 1 PMID:16551686 -1.2.1.44 feruloyl-coa arabidopsis thaliana 1.9 0.038 3 PMID:11430991;PMID:16122934 -1.2.1.44 feruloyl-coa fragaria x ananassa 0.00234 0.00234 1 PMID:25346738 -1.2.1.44 feruloyl-coa leucaena leucocephala 164.0 163.0 2 PMID:23541561;PMID:23688416 -1.2.1.44 feruloyl-coa oryza sativa japonica group 0.377 0.191 3 PMID:29312373 -1.2.1.44 feruloyl-coa panicum virgatum 2.01 1.0365 2 PMID:19761442 -1.2.1.44 feruloyl-coa petunia x hybrida 5.8 5.8 1 PMID:25217505 -1.2.1.44 feruloyl-coa populus tomentosa 1.033 0.6064999999999999 2 PMID:27580618 -1.2.1.44 feruloyl-coa populus tremuloides 7.8 7.8 1 PMID:15870094 -1.2.1.44 feruloyl-coa selaginella moellendorffii 0.289 0.26449999999999996 2 PMID:28321576 -1.2.1.44 feruloyl-coa solanum lycopersicum 14.2 7.8999999999999995 2 PMID:16551686 -1.2.1.44 feruloyl-coa sorghum bicolor 3.96 3.96 1 PMID:27956488 -1.2.1.44 p-coumaroyl-coa arabidopsis thaliana 1.63 1.63 1 PMID:16122934 -1.2.1.44 sinapaldehyde leucaena leucocephala 210.0 145.5 2 PMID:23541561 -1.2.1.44 sinapoyl-coa arabidopsis thaliana 1.67 0.0612 3 PMID:11430991;PMID:16122934 -1.2.1.44 sinapoyl-coa leucaena leucocephala 131.0 131.0 1 PMID:23541561 -1.2.1.44 sinapoyl-coa oryza sativa japonica group 0.57 0.094 3 PMID:29312373 -1.2.1.44 sinapoyl-coa panicum virgatum 0.2 0.10650000000000001 2 PMID:19761442 -1.2.1.44 sinapoyl-coa petunia x hybrida 3.4 3.4 1 PMID:25217505 -1.2.1.44 sinapoyl-coa populus tomentosa 0.064 0.064 1 PMID:27580618 -1.2.1.44 sinapoyl-coa populus tremuloides 5.3 5.3 1 PMID:15870094 -1.2.1.44 sinapoyl-coa selaginella moellendorffii 0.829 0.5449999999999999 2 PMID:28321576 -1.2.1.44 sinapoyl-coa solanum lycopersicum 0.96 0.96 1 PMID:16551686 -1.2.1.46 formaldehyde pseudomonas putida 0.48 0.212 4 * -1.2.1.46 formate pseudomonas sp. 0.43 0.43 1 * -1.2.1.48 (11z)-hexadec-11-enal homo sapiens 1.4 1.4 1 PMID:18035827 -1.2.1.48 decanal homo sapiens 2.18 2.18 1 PMID:18035827 -1.2.1.48 dodecanal homo sapiens 2.23 2.23 1 PMID:18035827 -1.2.1.48 farnesal homo sapiens 0.93 0.93 1 PMID:18035827 -1.2.1.48 hexadecanal homo sapiens 0.95 0.95 1 PMID:18035827 -1.2.1.48 nad+ homo sapiens 1.28 1.28 1 PMID:18035827 -1.2.1.48 octadecanal homo sapiens 1.52 1.52 1 PMID:18035827 -1.2.1.48 tetradecanal homo sapiens 0.86 0.86 1 PMID:18035827 -1.2.1.5 4-hydroxy-2-nonenal mus musculus 26.1 26.1 1 PMID:8401311 -1.2.1.5 acetaldehyde bacillus cereus 0.183 0.183 1 PMID:27107124 -1.2.1.5 acetaldehyde bacillus licheniformis 4.46 2.785 2 PMID:20495892 -1.2.1.5 acetaldehyde homo sapiens 35.9 35.9 1 PMID:8260946 -1.2.1.5 acetaldehyde mus musculus 33.5 33.5 1 PMID:8401311 -1.2.1.5 acetaldehyde sulfurisphaera tokodaii 1.14 1.14 1 PMID:23224332 -1.2.1.5 all-trans-retinal bacillus cereus 0.005 0.005 1 PMID:27107124 -1.2.1.5 benzaldehyde bacillus cereus 0.217 0.217 1 PMID:27107124 -1.2.1.5 benzaldehyde homo sapiens 51.0 51.0 1 PMID:8260946 -1.2.1.5 benzaldehyde mus musculus 20.9 20.9 1 PMID:8401311 -1.2.1.5 butyraldehyde bacillus licheniformis 32.8 22.15 2 PMID:20495892 -1.2.1.5 chloroacetaldehyde homo sapiens 7.7 7.7 1 PMID:23295226 -1.2.1.5 d-glyceraldehyde sulfurisphaera tokodaii 0.92 0.92 1 PMID:23224332 -1.2.1.5 d-glyceraldehyde 3-phosphate sulfurisphaera tokodaii 0.83 0.83 1 PMID:23224332 -1.2.1.5 hexanal homo sapiens 34.0 34.0 1 PMID:8260946;PMID:8401311 -1.2.1.5 hexanal mus musculus 34.0 34.0 1 PMID:8260946;PMID:8401311 -1.2.1.5 isovaleraldehyde bacillus licheniformis 3.58 2.245 2 PMID:20495892 -1.2.1.5 nad+ bacillus cereus 0.0017 0.0017 1 PMID:27107124 -1.2.1.5 nad+ homo sapiens 45.3 26.5 2 PMID:23295226;PMID:8260946 -1.2.1.5 nad+ mus musculus 18.8 18.8 1 PMID:8401311 -1.2.1.5 nad+ sulfurisphaera tokodaii 2.05 2.05 1 PMID:23224332 -1.2.1.5 nadp+ homo sapiens 38.8 38.8 1 PMID:8260946 -1.2.1.5 nadp+ mus musculus 33.1 33.1 1 PMID:8401311 -1.2.1.5 nadp+ sulfurisphaera tokodaii 3.71 3.71 1 PMID:23224332 -1.2.1.5 propionaldehyde bacillus licheniformis 49.38 31.37 2 PMID:20495892 -1.2.1.5 trans-2-hexenal homo sapiens 53.0 53.0 1 PMID:8260946 -1.2.1.5 trans-2-hexenal mus musculus 35.1 35.1 1 PMID:8401311 -1.2.1.5 valeraldehyde bacillus licheniformis 30.99 25.2 2 PMID:20495892 -1.2.1.57 acetyl-coa levilactobacillus brevis 0.26 0.26 1 * -1.2.1.57 butanoyl-coa levilactobacillus brevis 3.37 3.37 1 * -1.2.1.58 benzyl viologen aromatoleum evansii 46.0 46.0 1 PMID:9490067 -1.2.1.60 5-carboxymethyl-2-hydroxymuconate semialdehyde pseudomonas putida 40.0 40.0 1 * -1.2.1.65 2-naphthaldehyde pseudomonas sp. 96.0 96.0 1 PMID:24122667 -1.2.1.65 3-chlorobenzaldehyde pseudomonas sp. 65.0 65.0 1 PMID:24122667 -1.2.1.65 3-hydroxybenzaldehyde pseudomonas sp. 18.0 18.0 1 PMID:24122667 -1.2.1.65 4-chlorobenzaldehyde pseudomonas sp. 98.0 98.0 1 PMID:24122667 -1.2.1.65 4-nitrobenzaldehyde pseudomonas sp. 59.0 59.0 1 PMID:24122667 -1.2.1.65 benzaldehyde pseudomonas sp. 26.4 26.4 1 PMID:24122667 -1.2.1.65 nad+ alteromonas naphthalenivorans 234.3 234.3 1 PMID:28233868 -1.2.1.65 salicylaldehyde alteromonas naphthalenivorans 123.6 123.6 1 PMID:28233868 -1.2.1.65 salicylaldehyde pseudomonas sp. 93.6 93.6 1 PMID:24122667 -1.2.1.67 nad+ streptomyces sp. nl15-2k 23.45 23.45 1 PMID:30355315 -1.2.1.67 salicylaldehyde streptomyces sp. nl15-2k 14.91 14.91 1 PMID:30355315 -1.2.1.67 syringaldehyde sphingobium sp. syk-6 0.99 0.79 2 PMID:28294121 -1.2.1.67 vanillin sphingobium sp. syk-6 3.03 1.91 2 PMID:28294121 -1.2.1.67 vanillin streptomyces sp. nl15-2k 9.46 9.46 1 PMID:30355315 -1.2.1.7 3,4-dihydroxybenzaldehyde acinetobacter baylyi 25.0 25.0 1 * -1.2.1.7 4-hydroxy-3-methoxybenzaldehyde acinetobacter baylyi 18.0 18.0 1 * -1.2.1.7 4-hydroxybenzaldehyde acinetobacter baylyi 4.0 4.0 1 * -1.2.1.7 benzaldehyde acinetobacter baylyi 4.6 4.6 1 * -1.2.1.7 nad+ acinetobacter baylyi 14.0 14.0 1 * -1.2.1.70 l-glutamyl-trnaglu escherichia coli 0.13 0.13 1 PMID:12370189 -1.2.1.70 nadph escherichia coli 0.15 0.15 1 PMID:12370189 -1.2.1.72 d-erythrose 4-phosphate escherichia coli 200.0 110.0 2 PMID:7751290;PMID:9182530 -1.2.1.72 nad+ escherichia coli 169.0 94.5 2 PMID:7751290;PMID:9182530 -1.2.1.75 malonyl-coa chloroflexus aurantiacus 50.0 50.0 1 PMID:11948153 -1.2.1.75 malonyl-coa sulfurisphaera tokodaii 8.0 8.0 1 PMID:17041055 -1.2.1.75 nadph chloroflexus aurantiacus 18.6 13.205 2 PMID:24073271 -1.2.1.77 3,4-dehydroadipyl-coa semialdehyde aromatoleum evansii 45.0 45.0 1 PMID:16585753 -1.2.1.77 benzaldehyde paraburkholderia xenovorans 0.019 0.019 1 PMID:18462753 -1.2.1.77 formaldehyde paraburkholderia xenovorans 0.046 0.046 1 PMID:18462753 -1.2.1.77 heptaldehyde paraburkholderia xenovorans 29.9 29.9 1 PMID:18462753 -1.2.1.77 isovaleraldehyde paraburkholderia xenovorans 0.074 0.074 1 PMID:18462753 -1.2.1.77 nad+ paraburkholderia xenovorans 0.501 0.501 1 PMID:18462753 -1.2.1.77 nadp+ aromatoleum evansii 45.0 45.0 1 PMID:16585753 -1.2.1.77 nadp+ paraburkholderia xenovorans 0.04 0.04 1 PMID:18462753 -1.2.1.77 propionaldehyde paraburkholderia xenovorans 162.0 82.16 2 PMID:18462753;PMID:21495107 -1.2.1.77 valeraldehyde paraburkholderia xenovorans 5.16 5.16 1 PMID:18462753 -1.2.1.78 2-carboxybenzaldehyde nocardioides sp. 39.0 39.0 1 PMID:9335300 -1.2.1.78 2-nitrobenzaldehyde nocardioides sp. 48.0 48.0 1 PMID:9335300 -1.2.1.78 nad+ nocardioides sp. 32.0 32.0 1 PMID:9335300 -1.2.1.79 2,5-dioxopentanoate saccharolobus solfataricus 27.3 24.25 2 PMID:23296511 -1.2.1.79 glutaric semialdehyde physcomitrium patens 0.27 0.27 1 PMID:28749584 -1.2.1.79 nad+ physcomitrium patens 3.3 3.3 1 PMID:28749584 -1.2.1.79 nad+ saccharolobus solfataricus 136.3 136.3 1 PMID:23296511 -1.2.1.79 nad+ streptococcus pyogenes 1.94 1.94 1 PMID:25256219 -1.2.1.79 nadp+ acinetobacter baumannii 137.0 137.0 1 PMID:29734522 -1.2.1.79 nadp+ mycobacterium tuberculosis 2.7 2.0 2 PMID:21303655 -1.2.1.79 nadp+ physcomitrium patens 15.2 15.2 1 PMID:28749584 -1.2.1.79 nadp+ saccharolobus solfataricus 16.5 16.5 1 PMID:23296511 -1.2.1.79 nadp+ streptococcus pyogenes 7.2 7.2 1 PMID:25256219 -1.2.1.79 nadp+ synechococcus sp. 5.0 5.0 1 PMID:23589281 -1.2.1.79 succinate semialdehyde acinetobacter baumannii 137.0 137.0 1 PMID:29734522 -1.2.1.79 succinate semialdehyde physcomitrium patens 15.8 15.8 1 PMID:28749584 -1.2.1.79 succinate semialdehyde saccharolobus solfataricus 18.4 17.6 2 PMID:23296511 -1.2.1.79 succinate semialdehyde streptococcus pyogenes 1.69 1.69 1 PMID:25888791 -1.2.1.79 succinate semialdehyde synechocystis sp. pcc 6803 1.38 1.38 1 PMID:32227111 -1.2.1.79 succinic semialdehyde mycobacterium tuberculosis 4.7 3.3 2 PMID:21303655 -1.2.1.8 betaine aldehyde lycium ruthenicum 0.004 0.004 1 PMID:29297198 -1.2.1.8 betaine aldehyde spinacia oleracea 3.36 3.36 1 PMID:24884441 -1.2.1.8 betaine aldehyde staphylococcus aureus 11.0 11.0 2 PMID:24747910;PMID:25945581 -1.2.1.8 glycine betaine aspergillus nidulans 0.94 0.94 1 PMID:31061132 -1.2.1.8 glycine betaine aldehyde aspergillus nidulans 7.1 7.1 1 PMID:31061132 -1.2.1.8 n,n-dimethylglycine aspergillus nidulans 0.023 0.023 1 PMID:31061132 -1.2.1.8 nad+ pseudomonas aeruginosa 261.0 261.0 1 PMID:11104673 -1.2.1.8 nad+ spinacia oleracea 4.25 4.25 1 PMID:24884441 -1.2.1.8 nad+ staphylococcus aureus 6.18 6.18 1 PMID:25945581 -1.2.1.8 nadp+ pseudomonas aeruginosa 276.0 276.0 1 PMID:11104673 -1.2.1.8 nadp+ staphylococcus aureus 0.56 0.56 1 PMID:25945581 -1.2.1.80 hexacosanoyl-coa cryptosporidium parvum 0.077 0.077 1 PMID:21092192 -1.2.1.80 stearoyl-[acyl-carrier protein] nostoc punctiforme 0.0028 0.00155 2 PMID:25496470 -1.2.1.85 2-hydroxymuconate-6-semialdehyde pseudomonas putida 0.9 0.9 1 PMID:26032336 -1.2.1.87 acetaldehyde paraburkholderia xenovorans 17.2 17.2 2 PMID:19476337;PMID:21838275 -1.2.1.87 acetaldehyde thermus thermophilus 17.2 3.5 5 PMID:22316175 -1.2.1.87 acetyl-coa klebsiella pneumoniae 4.63 4.63 1 * -1.2.1.87 acetyl-coa listeria monocytogenes 11.33 11.33 1 * -1.2.1.87 acetyl-coa salmonella enterica 14.81 14.81 1 * -1.2.1.87 butanoyl-coa klebsiella pneumoniae 7.02 7.02 1 * -1.2.1.87 butanoyl-coa listeria monocytogenes 11.99 11.99 1 * -1.2.1.87 butanoyl-coa salmonella enterica 25.38 25.38 1 * -1.2.1.87 butyraldehyde paraburkholderia xenovorans 9.5 9.5 1 PMID:19476337 -1.2.1.87 isobutyraldehyde paraburkholderia xenovorans 11.2 11.2 1 PMID:19476337 -1.2.1.87 nad+ paraburkholderia xenovorans 14.1 14.1 1 PMID:19476337 -1.2.1.87 nadp+ paraburkholderia xenovorans 12.9 12.9 1 PMID:19476337 -1.2.1.87 propionaldehyde paraburkholderia xenovorans 16.3 16.3 2 PMID:19476337;PMID:21838275 -1.2.1.87 propionaldehyde thermus thermophilus 16.3 3.6 5 PMID:22316175 -1.2.1.88 1-pyrroline-5-carboxylate escherichia coli 5.16 5.16 1 PMID:24352662 -1.2.1.88 1-pyrroline-5-carboxylate saccharomyces cerevisiae 1.5 1.5 1 PMID:24502590 -1.2.1.88 1-pyrroline-5-carboxylate streptomyces coelicolor 25.0 25.0 1 * -1.2.1.88 1-pyrroline-5-carboxylate thermus thermophilus 1.6 1.6 1 PMID:16934832 -1.2.1.88 2-aminoadipic semialdehyde physcomitrium patens 0.005 0.005 1 PMID:30580036 -1.2.1.88 2-aminoadipic semialdehyde zea mays 0.04 0.04 1 PMID:30580036 -1.2.1.88 d-glyceraldehyde 3-phosphate zea mays 0.4 0.4 1 PMID:30580036 -1.2.1.88 glutaric semialdehyde physcomitrium patens 0.3 0.3 1 PMID:30580036 -1.2.1.88 glutaric semialdehyde zea mays 1.9 1.9 1 PMID:30580036 -1.2.1.88 l-glutamate 5-semialdehyde physcomitrium patens 0.44 0.44 1 PMID:30580036 -1.2.1.88 l-glutamate 5-semialdehyde trypanosoma cruzi 7.0 7.0 1 PMID:25623067 -1.2.1.88 l-glutamate 5-semialdehyde zea mays 6.8 6.8 1 PMID:30580036 -1.2.1.88 nad+ oryza sativa 12.0 12.0 1 PMID:26300893 -1.2.1.88 nad+ physcomitrium patens 0.17 0.17 1 PMID:30580036 -1.2.1.88 nad+ thermus thermophilus 1.6 1.6 1 PMID:16934832 -1.2.1.88 nad+ trypanosoma cruzi 7.5 7.5 1 PMID:25623067 -1.2.1.88 nad+ zea mays 3.1 3.1 1 PMID:30580036 -1.2.1.88 nadp+ oryza sativa 3.0 3.0 1 PMID:26300893 -1.2.1.88 nadp+ physcomitrium patens 0.05 0.05 1 PMID:30580036 -1.2.1.88 nadp+ thermus thermophilus 0.42 0.42 1 PMID:16934832 -1.2.1.88 nadp+ trypanosoma cruzi 1.2 1.2 1 PMID:25623067 -1.2.1.88 nadp+ zea mays 0.8 0.8 1 PMID:30580036 -1.2.1.89 d-glyceraldehyde picrophilus oshimae 10.0 10.0 1 PMID:16458304 -1.2.1.89 d-glyceraldehyde thermoplasma acidophilum 26.0 26.0 1 PMID:16458304 -1.2.1.89 d-glycerate picrophilus oshimae 12.0 12.0 1 PMID:16458304 -1.2.1.89 d-glycerate thermoplasma acidophilum 20.0 20.0 1 PMID:16458304 -1.2.1.89 glycolaldehyde picrophilus oshimae 20.0 20.0 1 PMID:16458304 -1.2.1.89 glycolaldehyde thermoplasma acidophilum 37.0 37.0 1 PMID:16458304 -1.2.1.89 nad+ thermoplasma acidophilum 1.64 1.64 2 PMID:24034429 -1.2.1.89 nadp+ picrophilus oshimae 10.0 10.0 1 PMID:16458304 -1.2.1.89 nadp+ thermoplasma acidophilum 25.0 25.0 1 PMID:16458304 -1.2.1.9 d-glyceraldehyde 3-phosphate saccharolobus solfataricus 15.0 15.0 1 PMID:24491524 -1.2.1.9 d-glyceraldehyde 3-phosphate sulfurisphaera tokodaii 341.0 341.0 1 PMID:24491524 -1.2.1.9 d-glyceraldehyde-3-phosphate streptococcus mutans 60.0 60.0 1 PMID:12163495 -1.2.1.90 d-glyceraldehyde 3-phosphate nitrosomonas europaea 0.0167 0.015 2 PMID:30690134 -1.2.1.90 l-glyceraldehyde 3-phosphate nitrosomonas europaea 0.007 0.007 1 PMID:30690134 -1.2.1.90 nad+ nitrosomonas europaea 0.0167 0.0167 1 PMID:30690134 -1.2.1.90 nadp+ nitrosomonas europaea 0.0133 0.0133 1 PMID:30690134 -1.2.1.92 3,6-anhydro-alpha-l-galactopyranose vibrio sp. ejy3 0.006 0.006 1 PMID:28482192 -1.2.1.92 3,6-anhydro-alpha-l-galactopyranose vibrio variabilis 58.29 58.29 2 PMID:32087198 -1.2.1.92 nadp+ vibrio variabilis 69.09 69.09 2 PMID:32087198 -1.2.1.95 adipate saccharomyces cerevisiae 0.0045 0.0045 1 PMID:10320345 -1.2.1.95 d-2-aminoadipate saccharomyces cerevisiae 0.63 0.63 1 PMID:10320345 -1.2.1.95 l-2-aminoadipate penicillium chrysogenum 1.1 1.1 1 PMID:12509419 -1.2.1.95 l-2-aminoadipate saccharomyces cerevisiae 41.7 41.7 1 PMID:10320345 -1.2.1.95 s-carboxymethyl-l-cysteine saccharomyces cerevisiae 6.0 6.0 1 PMID:10320345 -1.2.1.96 4-hydroxy-3-methylbenzaldehyde pseudomonas putida 0.071 0.03634999999999999 2 * -1.2.1.96 4-hydroxybenzaldehyde pseudomonas putida 0.26 0.13085 2 * -1.2.1.97 (2s)-3-sulfolactaldehyde pseudomonas putida 11.8 11.600000000000001 2 PMID:26195800 -1.2.1.99 3-hydroxypropionaldehyde escherichia coli 28.54 16.725 2 PMID:18668238 -1.2.1.99 3-hydroxypropionaldehyde klebsiella pneumoniae 19.81 19.81 1 * -1.2.1.99 3-hydroxypropionate escherichia coli 0.26 0.26 1 PMID:18668238 -1.2.1.99 acetaldehyde escherichia coli 11.03 11.03 1 PMID:18668238 -1.2.1.99 benzaldehyde escherichia coli 17.37 17.37 1 PMID:18668238 -1.2.1.99 butyraldehyde escherichia coli 26.95 26.95 1 PMID:18668238 -1.2.1.99 butyraldehyde klebsiella pneumoniae 30.34 30.34 1 * -1.2.1.99 isovaleraldehyde escherichia coli 27.31 27.31 1 PMID:18668238 -1.2.1.99 isovaleraldehyde klebsiella pneumoniae 25.47 25.47 1 * -1.2.1.99 propionaldehyde escherichia coli 24.35 24.35 1 PMID:18668238 -1.2.1.99 valeraldehyde escherichia coli 26.24 26.24 1 PMID:18668238 -1.2.1.99 valeraldehyde klebsiella pneumoniae 29.61 29.61 1 * -1.2.3.1 2,4-dihydroxybenzaldehyde mus musculus 3.39 1.755 4 PMID:29370288 -1.2.3.1 2-hydroxypyrimidine mus musculus 21.32 14.1 2 PMID:21705476 -1.2.3.1 2-methoxybenzaldehyde mus musculus 6.89 6.89 3 PMID:29370288 -1.2.3.1 3-methoxybenzaldehyde mus musculus 6.2 4.3 3 PMID:29370288 -1.2.3.1 4-(dimethylamino)cinnamaldehyde mus musculus 1.94 0.75 5 PMID:28526768;PMID:29370288 -1.2.3.1 4-hydroxybenzaldehyde mus musculus 4.31 1.425 4 PMID:29370288 -1.2.3.1 4-methoxybenzaldehyde mus musculus 7.37 3.75 3 PMID:29370288 -1.2.3.1 4-nitrobenzaldehyde mus musculus 2.41 1.8450000000000002 4 PMID:29370288 -1.2.3.1 5-nitroquinoline homo sapiens 1.31 0.1565 4 PMID:28888950 -1.2.3.1 acetaldehyde mus musculus 8.66 5.81 5 PMID:19401776;PMID:29370288 -1.2.3.1 allopurinol mus musculus 1.22 1.22 1 PMID:24358164 -1.2.3.1 benzaldehyde arabidopsis thaliana 95.2 95.2 1 PMID:19297586 -1.2.3.1 benzaldehyde mus musculus 5.29 2.167 9 PMID:19401776;PMID:21705476;PMID:23019336;PMID:24358164;PMID:29370288 -1.2.3.1 butanal mus musculus 6.4 2.2215 6 PMID:21705476;PMID:29370288 -1.2.3.1 cinnamaldehyde mus musculus 2.95 2.73 3 PMID:29370288 -1.2.3.1 cinnamylaldehyde arabidopsis thaliana 436.5 436.5 1 PMID:19297586 -1.2.3.1 crotonaldehyde mus musculus 8.32 4.935 4 PMID:29370288 -1.2.3.1 ethyl vanillin mus musculus 6.35 1.48 3 PMID:29370288 -1.2.3.1 heptanal mus musculus 4.49 0.62 4 PMID:29370288 -1.2.3.1 hexanal mus musculus 4.56 1.3499999999999999 4 PMID:29370288 -1.2.3.1 indole-3-acetaldehyde arabidopsis thaliana 1904.0 1904.0 1 PMID:19297586 -1.2.3.1 methotrexate homo sapiens 0.04 0.04 1 PMID:26032640 -1.2.3.1 methotrexate oryctolagus cuniculus 84.0 84.0 1 PMID:26032640 -1.2.3.1 n-methylnicotinamide oryctolagus cuniculus 1.97 1.475 4 PMID:8262244 -1.2.3.1 n1-methyl-nicotineamide mus musculus 0.4 0.4 1 PMID:24358164 -1.2.3.1 n1-methylnicotinamide mus musculus 0.82 0.33 3 PMID:23019336;PMID:28526768 -1.2.3.1 octanal mus musculus 4.77 0.775 4 PMID:29370288 -1.2.3.1 pentanal mus musculus 4.34 2.16 4 PMID:29370288 -1.2.3.1 phenanthridine mus musculus 2.35 1.96 5 PMID:23019336;PMID:24358164;PMID:29370288 -1.2.3.1 phenylacetaldehyde mus musculus 4.66 2.135 4 PMID:29370288 -1.2.3.1 phenylpropionaldehyde mus musculus 6.32 1.42 4 PMID:29370288 -1.2.3.1 phthalazine mus musculus 5.52 1.62 7 PMID:19401776;PMID:23019336;PMID:24358164;PMID:29370288 -1.2.3.1 propionaldehyde mus musculus 5.06 1.9 4 PMID:29370288 -1.2.3.1 purine mus musculus 7.86 4.66 4 PMID:29370288 -1.2.3.1 retinalaldehyde mus musculus 2.05 0.32499999999999996 4 PMID:28526768 -1.2.3.1 retinaldehyde mus musculus 0.83 0.83 1 PMID:19401776 -1.2.3.1 salicylaldehyde mus musculus 3.7 3.485 6 PMID:28526768;PMID:29370288 -1.2.3.1 vanillin mus musculus 7.5 1.34 5 PMID:28526768;PMID:29370288 -1.2.3.15 5-hydroxymethylfurfural thermothelomyces thermophilus 15.9 15.9 1 * -1.2.3.15 glycerol thermothelomyces thermophilus 34.1 34.1 1 * -1.2.3.15 methylglyoxal phanerodontia chrysosporium 198.0 198.0 1 PMID:11607073 -1.2.3.15 methylglyoxal thermothelomyces thermophilus 12.6 12.6 1 * -1.2.3.3 pyruvate lactiplantibacillus plantarum 35.0 16.95 6 PMID:10978159;PMID:16201755;PMID:9582325 -1.2.3.3 pyruvate lactobacillus delbrueckii 6.85 3.61 2 PMID:32448120 -1.2.3.4 oxalate brucella intermedia 85.0 85.0 1 PMID:26796139 -1.2.3.4 oxalate gelatoporia subvermispora 20.0 20.0 1 PMID:24953692 -1.2.3.4 oxalate hordeum vulgare 9.7 9.7 1 PMID:17210574 -1.2.4.1 2-oxobutanoate pseudomonas putida 0.17 0.17 1 * -1.2.4.1 2-oxovalerate pseudomonas putida 0.128 0.128 1 * -1.2.4.1 e2p lipoyl domain escherichia coli 95.0 95.0 1 PMID:23088422 -1.2.4.1 lipoyl domain azotobacter vinelandii 1.1 1.0 2 PMID:10518807 -1.2.4.1 pyruvate escherichia coli 37.9 37.9 1 PMID:17635929 -1.2.4.1 pyruvate geobacillus stearothermophilus 0.48 0.48 2 PMID:12603319;PMID:12795594 -1.2.4.1 pyruvate homo sapiens 0.077 0.077 1 PMID:17042496 -1.2.4.1 pyruvate pseudomonas putida 0.05 0.05 1 * -1.2.4.1 thiamine diphosphate geobacillus stearothermophilus 0.46 0.46 1 PMID:12603319 -1.2.4.2 2-oxo-5-hexenoic acid escherichia coli 0.0595 0.0595 1 * -1.2.4.2 2-oxoadipate homo sapiens 3.6 3.55 2 PMID:28435050 -1.2.4.2 2-oxoglutarate escherichia coli 35.0 18.85 2 * -1.2.4.2 2-oxoglutarate homo sapiens 21.3 18.4 3 PMID:28435050;PMID:29191460 -1.2.4.2 2-oxoglutarate picosynechococcus sp. pcc 7002 1.2 1.2 1 PMID:29574001 -1.2.4.2 2-oxovalerate escherichia coli 0.152 0.152 1 * -1.2.4.4 2-oxo-isovalerate homo sapiens 9.4 5.975 4 PMID:12902323;PMID:15166214;PMID:15576032;PMID:17329260 -1.2.4.4 alpha-ketoisovaleric acid homo sapiens 0.1983 0.1983 1 PMID:16472748 -1.2.4.4 thiamine diphosphate homo sapiens 6.38 3.2885 2 PMID:12902323;PMID:15166214 -1.2.5.1 ferricyanide escherichia coli 883.0 471.5 2 PMID:13785427 -1.2.5.1 pyruvate escherichia coli 167.0 167.0 1 PMID:13785427 -1.2.5.2 acetic acid gluconacetobacter diazotrophicus 22000.0 22000.0 1 PMID:20802042 -1.2.5.3 co afipia carboxidovorans 93.3 51.1 3 PMID:20178978;PMID:29676148 -1.2.7.1 2-oxobutyrate methanococcus maripaludis 13.0 13.0 1 PMID:12743680 -1.2.7.1 coa citrobacter sp. 109.0 74.0 2 PMID:28040649 -1.2.7.1 oxaloacetate methanococcus maripaludis 18.0 18.0 1 PMID:12743680 -1.2.7.1 pyruvate citrobacter sp. 94.0 64.5 2 PMID:28040649 -1.2.7.1 pyruvate methanococcus maripaludis 27.0 27.0 1 PMID:12743680 -1.2.7.10 oxalate neomoorella thermoacetica 0.09 0.09 1 PMID:20956531 -1.2.7.11 2-oxobutanoate saccharolobus solfataricus 1.5 1.5 1 PMID:16466637 -1.2.7.11 2-oxobutyrate saccharolobus solfataricus 1.55 1.55 1 PMID:16466637 -1.2.7.11 2-oxoglutarate saccharolobus solfataricus 7.53 7.515000000000001 2 PMID:16466637 -1.2.7.11 2-oxoglutarate sulfolobus sp. 19.0 18.0 2 PMID:11683888 -1.2.7.11 pyruvate saccharolobus solfataricus 2.4 2.4 1 PMID:16466637 -1.2.7.11 pyruvate sulfolobus sp. 51.0 49.5 2 PMID:11683888 -1.2.7.12 formylmethanofuran methanosarcina barkeri 640.0 640.0 1 PMID:2125267 -1.2.7.3 2-oxoglutarate magnetococcus marinus 30.3 22.2 3 PMID:31080943 -1.2.7.3 2-oxoglutarate thauera aromatica 17.0 17.0 1 PMID:12081970 -1.2.7.3 coa magnetococcus marinus 24.7 17.95 2 PMID:31080943 -1.2.7.3 oxidized ferredoxin magnetococcus marinus 12.3 12.3 1 PMID:31080943 -1.2.7.3 reduced ferredoxin magnetococcus marinus 0.51 0.51 1 PMID:31080943 -1.2.7.3 succinyl-coa magnetococcus marinus 0.45 0.45 1 PMID:31080943 -1.2.7.4 co carboxydothermus hydrogenoformans 15900.0 8700.0 2 PMID:18589895 -1.2.7.4 co neomoorella thermoacetica 3250.0 17.5 10 PMID:15839681;PMID:2905170;PMID:2984190;PMID:7794899;PMID:8038160;PMID:9287167 -1.2.7.4 methylene blue afipia carboxidovorans 93.3 57.8 3 PMID:20178978;PMID:21774528 -1.2.7.5 acetaldehyde aromatoleum aromaticum 103.0 73.0 2 PMID:30766522 -1.2.7.5 acetaldehyde thermococcus sp. 343.0 343.0 1 PMID:7642503 -1.2.7.5 acetate thermococcus sp. 1.6 1.6 1 PMID:7642503 -1.2.7.5 benzaldehyde aromatoleum aromaticum 92.0 63.5 2 PMID:30766522 -1.2.7.5 benzaldehyde thermococcus sp. 720.0 720.0 1 PMID:7642503 -1.2.7.5 benzyl viologen thermococcus sp. 250.0 250.0 1 PMID:7642503 -1.2.7.5 crotonaldehyde thermococcus sp. 269.0 145.5 2 PMID:7642503 -1.2.7.5 formaldehyde thermococcus sp. 950.0 950.0 1 PMID:7642503 -1.2.7.5 glyceraldehyde thermococcus sp. 2.8 2.8 1 PMID:7642503 -1.2.7.5 indoleacetaldehyde thermococcus sp. 55.0 55.0 1 PMID:7642503 -1.2.7.5 isovalerylaldehyde thermococcus sp. 272.0 272.0 1 PMID:7642503 -1.2.7.5 methyl viologen thermococcus sp. 62.0 62.0 1 PMID:7642503 -1.2.7.5 nad+ aromatoleum aromaticum 54.0 54.0 1 PMID:30766522 -1.2.7.5 oxidized benzyl viologen aromatoleum aromaticum 91.0 91.0 1 PMID:30766522 -1.2.7.5 oxidized ferredoxin caldicellulosiruptor bescii 5.57 5.57 1 PMID:31097544 -1.2.7.5 oxidized ferredoxin thermococcus sp. 270.0 270.0 1 PMID:7642503 -1.2.7.5 phenylacetaldehyde aromatoleum aromaticum 81.0 60.5 2 PMID:30766522 -1.2.7.5 phenylacetaldehyde thermococcus sp. 960.0 960.0 1 PMID:7642503 -1.2.7.5 propionaldehyde thermococcus sp. 1100.0 1100.0 1 PMID:7642503 -1.2.7.5 salicylaldehyde thermococcus sp. 13.0 13.0 1 PMID:7642503 -1.2.7.6 oxidized ferredoxin caldicellulosiruptor bescii 5.57 5.57 1 PMID:31097544 -1.2.7.7 2-keto-3-methylvalerate pyrococcus sp. 2.07 2.07 1 PMID:8550513 -1.2.7.7 2-keto-3-methylvalerate thermococcus litoralis 1.27 1.27 1 PMID:8550513 -1.2.7.7 2-ketobutyrate pyrococcus sp. 1.47 1.47 1 PMID:8550513 -1.2.7.7 2-ketobutyrate thermococcus litoralis 22.3 22.3 1 PMID:8550513 -1.2.7.7 2-ketocaproate pyrococcus sp. 0.933 0.933 1 PMID:8550513 -1.2.7.7 2-ketocaproate thermococcus litoralis 1.0 1.0 1 PMID:8550513 -1.2.7.7 2-ketoisocaproate pyrococcus sp. 2.47 2.47 1 PMID:8550513 -1.2.7.7 2-ketoisocaproate thermococcus litoralis 2.0 2.0 1 PMID:8550513 -1.2.7.7 2-ketoisovalerate pyrococcus sp. 3.67 3.67 1 PMID:8550513 -1.2.7.7 2-ketoisovalerate thermococcus litoralis 3.0 3.0 1 PMID:8550513 -1.2.7.7 3-methyl-2-oxobutanoate pyrococcus sp. 1.07 1.07 1 PMID:8550513 -1.2.7.7 4-methylthio-2-oxobutanoate thermococcus litoralis 0.667 0.667 1 PMID:8550513 -1.2.7.7 coa pyrococcus sp. 5.6 5.6 1 PMID:8550513 -1.2.7.7 coa thermococcus litoralis 5.0 5.0 1 PMID:8550513 -1.2.7.7 glyoxylate thermococcus litoralis 0.0133 0.0133 1 PMID:8550513 -1.2.7.7 hydroxyphenylpyruvate thermococcus litoralis 0.833 0.833 1 PMID:8550513 -1.2.7.7 indolpyruvate thermococcus litoralis 0.433 0.433 1 PMID:8550513 -1.2.7.7 oxidized ferredoxin thermococcus litoralis 1.53 1.53 1 PMID:8550513 -1.2.7.7 phenylglyoxalate thermococcus litoralis 0.833 0.833 1 PMID:8550513 -1.2.7.7 phenylglyoxylate pyrococcus sp. 1.33 1.33 1 PMID:8550513 -1.2.7.7 phenylpyruvate pyrococcus sp. 0.467 0.467 1 PMID:8550513 -1.2.7.7 phenylpyruvate thermococcus litoralis 0.6 0.6 1 PMID:8550513 -1.2.7.7 pyruvate pyrococcus sp. 1.73 1.73 1 PMID:8550513 -1.2.7.7 pyruvate thermococcus litoralis 0.267 0.267 1 PMID:8550513 -1.2.98.1 butanal homo sapiens 21.7 1.25 3 PMID:8843167 -1.2.98.1 formaldehyde methylobacterium sp. fd1 7500.0 4300.0 3 PMID:32281473 -1.2.99.6 acetaldehyde thermococcus sp. 343.0 172.3 2 PMID:7642503 -1.2.99.6 benzaldehyde megalodesulfovibrio gigas 1.35 1.3 2 PMID:12890482 -1.2.99.6 benzaldehyde thermococcus sp. 720.0 720.0 1 PMID:7642503 -1.2.99.6 benzyl viologen thermococcus sp. 250.0 250.0 1 PMID:7642503 -1.2.99.6 crotonaldehyde thermococcus sp. 269.0 145.5 2 PMID:7642503 -1.2.99.6 decylaldehyde megalodesulfovibrio gigas 1.22 1.205 2 PMID:12890482 -1.2.99.6 es-1 ferredoxin thermococcus sp. 270.0 270.0 1 PMID:7642503 -1.2.99.6 glyceraldehyde thermococcus sp. 10.5 10.5 1 PMID:7642503 -1.2.99.6 indolecetaldehyde thermococcus sp. 55.0 55.0 1 PMID:7642503 -1.2.99.6 isovaleraldehyde thermococcus sp. 272.0 272.0 1 PMID:7642503 -1.2.99.6 methanal thermococcus sp. 950.0 950.0 1 PMID:7642503 -1.2.99.6 methyl viologen thermococcus sp. 62.0 62.0 1 PMID:7642503 -1.2.99.6 octaldehyde megalodesulfovibrio gigas 1.2 1.0 2 PMID:12890482 -1.2.99.6 phenylacetaldehyde thermococcus sp. 960.0 960.0 1 PMID:7642503 -1.2.99.6 propanal thermococcus sp. 1100.0 1100.0 1 PMID:7642503 -1.2.99.6 salicylaldehyde thermococcus sp. 13.0 13.0 1 PMID:7642503 -1.2.99.7 2,3-dihydroxybenzaldehyde megalodesulfovibrio gigas 0.87 0.87 1 PMID:25261288 -1.2.99.7 2,5-dihydroxybenzaldehyde megalodesulfovibrio gigas 3.3 3.3 1 PMID:25261288 -1.2.99.7 2-phenylacetaldehyde megalodesulfovibrio gigas 4.4 4.4 1 PMID:25261288 -1.2.99.7 3-hydroxybenzaldehyde megalodesulfovibrio gigas 3.6 3.6 1 PMID:25261288 -1.2.99.7 3-phenylpropanal megalodesulfovibrio gigas 2.1 2.1 1 PMID:25261288 -1.2.99.7 acetaldehyde megalodesulfovibrio gigas 1.14 0.6299999999999999 2 PMID:2821990;PMID:8218223 -1.2.99.7 benzaldehyde megalodesulfovibrio gigas 5.7 1.43 3 PMID:19459677;PMID:25261288;PMID:8218223 -1.2.99.7 benzaldehyde oleidesulfovibrio alaskensis 0.96 0.96 1 PMID:10727945 -1.2.99.7 cinnamaldehyde megalodesulfovibrio gigas 0.58 0.58 1 PMID:25261288 -1.2.99.7 propionaldehyde megalodesulfovibrio gigas 0.44 0.2235 2 PMID:2821990;PMID:8218223 -1.2.99.7 salicylaldehyde megalodesulfovibrio gigas 0.44 0.25 3 PMID:25261288;PMID:2821990;PMID:8218223 -1.2.99.8 acetaldehyde sulfurisphaera tokodaii 3.38 3.3049999999999997 2 PMID:26808202 -1.2.99.8 d-glyceraldehyde sulfurisphaera tokodaii 50.5 4.505 6 PMID:26808202 -1.2.99.8 d-glyceraldehyde-3-phosphate sulfurisphaera tokodaii 0.98 0.65 3 PMID:26808202 -1.2.99.8 indoleacetaldehyde sulfurisphaera tokodaii 3.58 3.46 3 PMID:26808202 -1.2.99.8 indolepyruvate sulfurisphaera tokodaii 11.0 11.0 1 PMID:26808202 -1.20.1.1 nad+ ralstonia sp. 4506 2.117 2.117 1 PMID:33869158 -1.20.1.1 nad+ stutzerimonas stutzeri 4.4 2.93 3 PMID:14529270;PMID:16204481;PMID:16724915 -1.20.1.1 nadp+ ralstonia sp. 4506 0.267 0.267 1 PMID:33869158 -1.20.1.1 nadp+ stutzerimonas stutzeri 1.41 1.4049999999999998 2 PMID:14529270;PMID:16724915 -1.20.1.1 phosphite stutzerimonas stutzeri 7.33 3.65 5 PMID:11278981;PMID:17615560;PMID:17949110 -1.20.1.1 phosphonate cupriavidus metallidurans 6.83 6.83 1 PMID:22564138 -1.20.1.1 phosphonate methylorubrum extorquens 5.1 5.1 1 PMID:22564138 -1.20.1.1 phosphonate nostoc punctiforme 3.36 3.36 1 PMID:22564138 -1.20.1.1 phosphonate ralstonia sp. 4506 2.625 2.625 1 PMID:34900961 -1.20.1.1 phosphonate stutzerimonas stutzeri 6.57 3.2 3 PMID:15779903;PMID:22564138;PMID:27900443 -1.20.2.1 arsenite arsenite-oxidising bacterium 8.6 8.6 1 PMID:14996791 -1.20.2.1 arsenite hydrogenophaga sp. 30.4 30.4 1 PMID:15178476 -1.20.2.1 arsenite pseudorhizobium banfieldiae 8.6 8.6 1 PMID:14996791 -1.20.4.1 glutaredoxin 1 escherichia coli 0.3 0.3 1 PMID:10593884 -1.20.4.1 glutaredoxin 2 escherichia coli 0.14 0.14 1 PMID:10593884 -1.20.4.1 glutaredoxin 3 escherichia coli 0.09 0.09 1 PMID:10593884 -1.20.4.3 2-hydroxyethyl disulfide-mycothiol corynebacterium glutamicum 104.48 57.25 4 PMID:34290951;PMID:34483223 -1.20.4.4 arsenate bacillus subtilis 2.0 1.6 4 PMID:16797027 -1.20.4.4 arsenate bacillus thuringiensis 0.00119 0.00119 1 PMID:34932145 -1.20.4.4 arsenate corynebacterium glutamicum 0.09 0.09 1 PMID:22032722 -1.20.4.4 arsenate oleidesulfovibrio alaskensis 3.2 2.9 3 PMID:25139711 -1.20.4.4 arsenate staphylococcus aureus 3.65 0.3725 8 PMID:10606519;PMID:16797027 -1.20.4.4 arsenate thermus thermophilus 0.75 0.75 1 PMID:23800470 -1.20.4.4 thioredoxin staphylococcus aureus 1.9 1.9 1 PMID:15147840 -1.20.9.1 arsenate chrysiogenes arsenatis 14400.0 14400.0 1 PMID:9738904 -1.20.9.1 azurin alcaligenes faecalis 27.0 27.0 1 PMID:1331097 -1.20.99.1 arsenate chrysiogenes arsenatis 14400.0 14400.0 1 PMID:9738904 -1.20.99.1 arsenate homo sapiens 0.03 0.021 4 PMID:20025242 -1.20.99.1 arsenate oryza sativa 0.33 0.23500000000000001 2 PMID:17388894 -1.20.99.1 arsenite hydrogenophaga sp. nt14 30.4 30.4 1 PMID:15178476 -1.20.99.1 reduced glutaredoxin oryza sativa 0.26 0.225 2 PMID:17388894 -1.21.1.1 2-iodophenol homo sapiens 0.0043 0.00415 2 PMID:28157283 -1.21.1.1 2-iodophenol thermotoga neapolitana 0.108 0.061 2 PMID:34748729 -1.21.1.1 3,5-diiodo-l-tyrosine bos taurus 10.0 10.0 1 PMID:500717 -1.21.1.1 3,5-diiodo-l-tyrosine mus musculus 0.16 0.12 3 PMID:16316988;PMID:22238141 -1.21.1.1 3-bromo-l-tyrosine drosophila melanogaster 0.069 0.069 1 PMID:27643701 -1.21.1.1 3-bromo-l-tyrosine thermotoga neapolitana 0.085 0.085 1 PMID:34748729 -1.21.1.1 3-chloro-l-tyrosine drosophila melanogaster 0.05 0.05 1 PMID:27643701 -1.21.1.1 3-chloro-l-tyrosine thermotoga neapolitana 0.048 0.048 1 PMID:34748729 -1.21.1.1 3-iodo-l-tyrosine bos taurus 18.0 18.0 1 PMID:500717 -1.21.1.1 3-iodo-l-tyrosine danio rerio 0.07 0.07 1 PMID:24153409 -1.21.1.1 3-iodo-l-tyrosine daphnia pulex 0.29 0.29 1 PMID:24153409 -1.21.1.1 3-iodo-l-tyrosine drosophila melanogaster 0.12 0.12 1 PMID:27643701 -1.21.1.1 3-iodo-l-tyrosine haliscomenobacter hydrossis 0.09 0.09 1 PMID:24153409 -1.21.1.1 3-iodo-l-tyrosine homo sapiens 0.217 0.155 4 PMID:25395621;PMID:28157283;PMID:30052294 -1.21.1.1 3-iodo-l-tyrosine hydra vulgaris 0.23 0.23 1 PMID:24153409 -1.21.1.1 3-iodo-l-tyrosine mus musculus 0.12 0.12 1 PMID:24153409 -1.21.1.1 3-iodo-l-tyrosine thermotoga neapolitana 0.45 0.23850000000000002 2 PMID:34748729 -1.21.3.1 n-[(5s)-5-amino-5-carboxypentanoyl]-l-cysteinyl-d-valine aspergillus nidulans 4.1 4.1 1 PMID:11094156 -1.21.3.10 gamma-l-glutamyl-l-cysteine neurospora crassa 0.461 0.461 1 PMID:25275953 -1.21.3.10 hercynine chloracidobacterium thermophilum 0.443 0.4415 2 PMID:32257583 -1.21.3.10 hercynine neurospora crassa 2.267 1.3639999999999999 2 PMID:25275953 -1.21.3.10 l-cysteine chloracidobacterium thermophilum 0.205 0.1725 2 PMID:30883103;PMID:32257583 -1.21.3.10 l-cysteine methylobacterium brachiatum 2.3 2.3 1 PMID:32436380 -1.21.3.10 l-cysteine methylobacterium pseudosasicola 2.1 2.1 1 PMID:32436380 -1.21.3.10 l-cysteine neurospora crassa 2.267 2.267 1 PMID:25275953 -1.21.3.3 (s)-reticuline eschscholzia californica 103.0 8.0 5 PMID:16728404;PMID:17573342;PMID:18953357;PMID:19457868;PMID:22931234 -1.21.3.3 (s)-scoulerine eschscholzia californica 0.0025 0.0025 1 PMID:19570558 -1.21.3.3 cellobiose arabidopsis thaliana 1.22 1.22 1 PMID:30664296 -1.21.3.3 cellohexaose arabidopsis thaliana 1.59 1.59 1 PMID:30664296 -1.21.3.3 cellopentaose arabidopsis thaliana 1.38 1.38 1 PMID:30664296 -1.21.3.3 cellotetraose arabidopsis thaliana 1.6 1.6 1 PMID:30664296 -1.21.3.3 cellotriose arabidopsis thaliana 4.49 4.49 1 PMID:30664296 -1.21.3.3 o2 eschscholzia californica 10.5 10.5 1 PMID:22931234 -1.21.3.7 cannabigerolate cannabis sativa 0.888 0.308 3 PMID:15190053;PMID:17669365;PMID:27369551 -1.21.3.8 cannabigerolate cannabis sativa 0.19 0.19 1 PMID:8663284 -1.21.3.8 cannabinerolate cannabis sativa 0.03 0.03 1 PMID:8663284 -1.21.4.5 2,3,5,6-tetrachlorohydroquinone sphingobium sp. ug30 48.5 29.05 2 PMID:12459186;PMID:19682569 -1.21.4.5 3,6-dichlorogentisate rhizorhabdus dicambivorans 7.15 7.15 1 PMID:29934333 -1.21.99.4 3,3',5'-triiodothyronine rattus sp. 0.00107 0.0007685 2 PMID:2153120 -1.21.99.5 tetrachloroethene sulfurospirillum multivorans 20.4 10.95 2 PMID:11976751 -1.23.1.1 (+)-pinoresinol camellia sinensis var. sinensis 0.171 0.09000000000000001 2 PMID:30844490 -1.23.1.1 (+)-pinoresinol thuja plicata 2.3 1.43 2 PMID:32201979 -1.23.1.2 (+)-lariciresinol camellia sinensis var. sinensis 0.655 0.655 1 PMID:30844490 -1.23.1.3 (-)-pinoresinol camellia sinensis var. sinensis 0.041 0.041 1 PMID:30844490 -1.23.1.3 (-)-pinoresinol thuja plicata 0.88 0.88 1 PMID:32201979 -1.23.1.4 (-)-lariciresinol camellia sinensis var. sinensis 0.197 0.197 1 PMID:30844490 -1.3.1.1 5,6-dihydrouracil escherichia coli 0.65 0.65 2 PMID:21169495 -1.3.1.1 dihydrothymine escherichia coli 0.28 0.28 2 PMID:21169495 -1.3.1.1 thymine escherichia coli 0.39 0.39 2 PMID:21169495 -1.3.1.1 uracil escherichia coli 0.64 0.64 2 PMID:21169495 -1.3.1.10 crotonyl-[acyl-carrier protein] staphylococcus aureus 0.51 0.51 1 PMID:24189061 -1.3.1.10 crotonyl-[staphylococcus aureus acyl carrier protein] staphylococcus aureus 11.6 11.6 1 PMID:18335995 -1.3.1.10 crotonyl-n-acetyl-cysteamine staphylococcus aureus 1.5 1.5 1 PMID:18335995 -1.3.1.10 dodec-2-enoyl-coa staphylococcus aureus 18.0 18.0 1 PMID:18335995 -1.3.1.10 dodecenoyl-[staphylococcus aureus acyl carrier protein] staphylococcus aureus 130.2 130.2 1 PMID:18335995 -1.3.1.10 dodecenoyl-n-acetyl-cysteamine staphylococcus aureus 30.4 30.4 1 PMID:18335995 -1.3.1.10 nadph staphylococcus aureus 130.2 130.2 1 PMID:18335995 -1.3.1.100 chanoclavine-i aldehyde aspergillus fumigatus 38.5 38.5 1 PMID:20102147 -1.3.1.102 (1r,2s,4s)-neoisodihydrocarveol nicotiana tabacum 0.003 0.003 1 PMID:11117876 -1.3.1.102 (1r,4s)-isodihydrocarvone nicotiana tabacum 0.003 0.003 1 PMID:11117876 -1.3.1.102 (2e)-3-methylpent-2-enal nicotiana tabacum 9.2 4.93 2 * -1.3.1.102 (2r,4r)-carveol nicotiana tabacum 0.02 0.02 1 PMID:11117876 -1.3.1.102 (2r,4s)-carveol nicotiana tabacum 0.025 0.025 1 PMID:11117876 -1.3.1.102 (2s,4r)-carveol nicotiana tabacum 0.097 0.097 1 PMID:11117876 -1.3.1.102 (2s,4s)-carveol nicotiana tabacum 0.077 0.077 1 PMID:11117876 -1.3.1.102 (r)-carvone nicotiana tabacum 0.032 0.022 2 PMID:11117876 -1.3.1.102 (r)-pulegone nicotiana tabacum 3.3 3.3 1 PMID:17945329 -1.3.1.102 (s)-carvone nicotiana tabacum 0.025 0.0175 2 PMID:11117876 -1.3.1.102 (s)-pulegone nicotiana tabacum 2.8 2.8 1 PMID:17945329 -1.3.1.102 1-nitrocyclohexene nicotiana tabacum 11.0 6.23 2 * -1.3.1.102 1-octen-3-one nicotiana tabacum 1.17 0.845 2 * -1.3.1.102 4-coumaryl aldehyde plagiochasma appendiculatum 0.278 0.188 2 PMID:23954295 -1.3.1.102 5-hydroxyconiferyl aldehyde plagiochasma appendiculatum 0.169 0.169 1 PMID:23954295 -1.3.1.102 caffeoyl aldehyde plagiochasma appendiculatum 0.238 0.185 2 PMID:23954295 -1.3.1.102 coniferyl aldehyde plagiochasma appendiculatum 0.118 0.118 1 PMID:23954295 -1.3.1.102 nadph nicotiana tabacum 1.3 1.3 1 * -1.3.1.102 trans-2-nonenal nicotiana tabacum 2.92 1.895 2 * -1.3.1.102 trans-cinnamaldehyde nicotiana tabacum 3.5 2.3 2 * -1.3.1.104 crotonyl-coa uncultured bacterium pbf1 0.009627 0.009627 1 PMID:29891603 -1.3.1.104 nadph uncultured bacterium pbf1 0.02764 0.02764 1 PMID:29891603 -1.3.1.105 (2e)-2-butylidene-4-hydroxy-5-methyl-3(2h)-furanone fragaria x ananassa 1.43 1.43 1 PMID:17636940 -1.3.1.105 (2e)-2-butylidene-4-hydroxy-5-methyl-3(2h)-furanone solanum lycopersicum 0.15 0.15 1 PMID:17636940 -1.3.1.105 (2e)-4-hydroxy-5-methyl-2-propylidene-3(2h)-furanone fragaria x ananassa 2.69 2.69 1 PMID:17636940 -1.3.1.105 (2e)-4-hydroxy-5-methyl-2-propylidene-3(2h)-furanone solanum lycopersicum 0.34 0.34 1 PMID:17636940 -1.3.1.105 (2e)-ethylidene-4-hydroxy-5-methyl-3(2h)-furanone fragaria x ananassa 1.94 1.94 1 PMID:17636940 -1.3.1.105 (2e)-ethylidene-4-hydroxy-5-methyl-3(2h)-furanone solanum lycopersicum 0.39 0.39 1 PMID:17636940 -1.3.1.109 butanoyl-coa clostridioides difficile 8.0 8.0 1 PMID:23772070 -1.3.1.117 nadph malus domestica 0.0023 0.0023 1 PMID:25152451 -1.3.1.117 trans-4-coumaroyl-coa malus domestica 0.0019 0.0019 1 PMID:25152451 -1.3.1.117 trans-feruloyl-coa malus domestica 0.0042 0.0042 1 PMID:25152451 -1.3.1.118 trans-2-dodecenoyl-coa mycobacterium tuberculosis 5.34 5.34 1 PMID:21143326 -1.3.1.119 3,6-dichlorobenzene cis-dihydrodiol xanthobacter flavus 14.5 14.5 1 PMID:8599538 -1.3.1.119 benzene cis-dihydrodiol xanthobacter flavus 27.8 27.8 1 PMID:8599538 -1.3.1.119 nad+ xanthobacter flavus 27.8 21.15 2 PMID:8599538 -1.3.1.12 l-arogenate aquifex aeolicus 68.0 6.4 6 PMID:16731976 -1.3.1.12 nad+ aquifex aeolicus 62.0 11.5 7 PMID:16731976;PMID:19279014 -1.3.1.12 nad+ escherichia coli 0.45 0.45 1 PMID:10200166;PMID:9843375 -1.3.1.12 nad+ mycobacterium tuberculosis 356.1 356.1 1 PMID:16889979 -1.3.1.12 nad+ streptococcus mutans 7.4 7.4 1 * -1.3.1.12 prephenate aquifex aeolicus 68.0 6.8 7 PMID:16731976;PMID:19279014 -1.3.1.12 prephenate bacillus anthracis 49.0 12.3 3 PMID:31750992 -1.3.1.12 prephenate escherichia coli 135.0 67.725 2 PMID:10200166;PMID:6395895;PMID:9843375 -1.3.1.12 prephenate haemophilus influenzae 35.0 35.0 1 PMID:28025081 -1.3.1.12 prephenate mycobacterium tuberculosis 170.4 170.4 1 PMID:16889979 -1.3.1.12 prephenate pleurotus ostreatus 3.09 3.09 1 PMID:30771296 -1.3.1.12 prephenate saccharomyces cerevisiae 0.1 0.1 1 PMID:30771296 -1.3.1.12 prephenate streptococcus mutans 10.5 10.5 1 * -1.3.1.12 prephenate uncultured bacterium 10.08 10.08 1 PMID:23479063 -1.3.1.122 (6e)-8-oxogeranial amborella trichopoda 0.321 0.321 1 PMID:32501002 -1.3.1.122 (6e)-8-oxogeranial arabidopsis thaliana 0.155 0.0785 2 PMID:32501002 -1.3.1.122 (6e)-8-oxogeranial catharanthus roseus 5.84 5.84 1 PMID:32501002 -1.3.1.122 (6e)-8-oxogeranial coccomyxa subellipsoidea 0.066 0.0455 2 PMID:32501002 -1.3.1.122 (6e)-8-oxogeranial digitalis lanata 0.064 0.064 1 PMID:32501002 -1.3.1.122 (6e)-8-oxogeranial digitalis purpurea 6.32 6.32 1 PMID:32501002 -1.3.1.122 (6e)-8-oxogeranial nepeta racemosa 0.6 0.6 1 PMID:29091815 -1.3.1.122 (6e)-8-oxogeranial selaginella moellendorffii 2.03 1.0179999999999998 2 PMID:32501002 -1.3.1.122 nadph nepeta racemosa 0.84 0.84 1 PMID:29091815 -1.3.1.123 (6e)-8-oxogeranial antirrhinum majus 0.72 0.72 1 PMID:28701463 -1.3.1.123 (6e)-8-oxogeranial plantago major 2.6 2.6 1 PMID:30287897 -1.3.1.123 (6e)-8-oxogeranial swertia mussotii 0.11 0.07200000000000001 2 PMID:28829394 -1.3.1.123 nadph swertia mussotii 0.135 0.0805 2 PMID:28829394 -1.3.1.124 2-trans,4-trans-hexadienoyl-coa rattus norvegicus 2.1 2.1 1 PMID:10497069 -1.3.1.125 acrylate vibrio harveyi 19.0 19.0 1 PMID:35612301 -1.3.1.125 methacrylate vibrio harveyi 2.5 2.5 1 PMID:35612301 -1.3.1.13 prephenate glycine max 26.3 21.3 2 PMID:25402771;PMID:29601138 -1.3.1.13 prephenate ignicoccus hospitalis 15.0 15.0 1 PMID:28025081 -1.3.1.13 prephenate medicago truncatula 21.8 21.8 1 PMID:25402771 -1.3.1.13 prephenate methanothrix harundinacea 2.44 2.44 1 PMID:29164132 -1.3.1.14 (s)-dihydroorotate lactococcus lactis 49.3 49.3 1 PMID:16624811 -1.3.1.14 l-dihydroorotate faecalicatena orotica 45.0 33.5 2 PMID:10956027 -1.3.1.14 nadh lactococcus lactis 25.7 25.7 1 PMID:16624811 -1.3.1.14 orotate faecalicatena orotica 3.97 3.97 1 PMID:10956027 -1.3.1.14 orotate lactococcus lactis 25.7 25.7 1 PMID:16624811 -1.3.1.15 orotate bacteria 11.7 11.7 1 PMID:13923427 -1.3.1.2 5,6-dihydrouracil bos taurus 0.4 0.4 1 PMID:8366081 -1.3.1.2 nadph sus scrofa 0.85 0.75 2 PMID:32516529 -1.3.1.2 thymine sus scrofa 0.42 0.405 2 PMID:32516529 -1.3.1.2 uracil bos taurus 1.6 1.6 1 PMID:8366081 -1.3.1.2 uracil sus scrofa 0.78 0.73 3 PMID:20831907;PMID:32516529 -1.3.1.20 (r)-tetralol macaca fascicularis 84.0 84.0 1 PMID:15618685 -1.3.1.20 (r)-tetralol macaca fuscata fuscata 2520.0 2520.0 1 PMID:15618685 -1.3.1.20 (s)-1-indanol bos taurus 0.417 0.417 1 PMID:7766669 -1.3.1.20 (s)-indan-1-ol homo sapiens 0.417 0.1605 8 PMID:10634139;PMID:8573067;PMID:9578563 -1.3.1.20 (s)-indan-1-ol macaca fascicularis 2040.0 2040.0 1 PMID:15618685 -1.3.1.20 (s)-indan-1-ol macaca fuscata fuscata 1200.0 1200.0 1 PMID:15618685 -1.3.1.20 (s)-tetralol macaca fascicularis 1320.0 1320.0 1 PMID:15618685 -1.3.1.20 (s)-tetralol macaca fuscata fuscata 2160.0 2160.0 1 PMID:15618685 -1.3.1.20 1-acenaphthenol bos taurus 2.0 2.0 1 PMID:7766669 -1.3.1.20 1-acenaphthenol homo sapiens 0.585 0.4535 4 PMID:9578563 -1.3.1.20 4-chromanol macaca fascicularis 2880.0 2880.0 1 PMID:15618685 -1.3.1.20 4-chromanol macaca fuscata fuscata 150.0 150.0 1 PMID:15618685 -1.3.1.20 4-nitrobenzaldehyde macaca fuscata 11.3 11.3 1 PMID:2697716 -1.3.1.20 5beta-androstan-3alpha,17beta-diol homo sapiens 0.108 0.108 1 PMID:10634139 -1.3.1.20 androsterone homo sapiens 0.0183 0.012485 2 PMID:9578563 -1.3.1.20 camphorquinone macaca fascicularis 20.0 20.0 1 PMID:18453689 -1.3.1.20 camphorquinone macaca fuscata 62.5 41.25 2 PMID:18453689;PMID:2697716 -1.3.1.20 chenodeoxycholic acid bos taurus 0.0115 0.0115 1 PMID:7766669 -1.3.1.20 cholic acid bos taurus 0.045 0.045 1 PMID:7766669 -1.3.1.20 cholic acid homo sapiens 0.233 0.233 1 PMID:10634139 -1.3.1.20 d-glyceraldehyde macaca fuscata 31.4 31.4 1 PMID:2697716 -1.3.1.20 d-xylose macaca fuscata 2.6 2.6 1 PMID:18453689 -1.3.1.20 deoxycholic acid bos taurus 0.133 0.133 1 PMID:7766669 -1.3.1.20 dihydroxyacetone macaca fuscata 5.5 5.5 1 PMID:2697716 -1.3.1.20 dihydroxyacetone phosphate macaca fuscata 4.3 4.3 1 PMID:2697716 -1.3.1.20 dl-glyceraldehyde-3-phosphate macaca fuscata 8.0 8.0 1 PMID:2697716 -1.3.1.20 l-glyceraldehyde macaca fuscata 9.1 9.1 1 PMID:2697716 -1.3.1.20 lithocholic acid bos taurus 0.0867 0.0466 2 PMID:7766669 -1.3.1.20 taurochenodeoxycholic acid bos taurus 0.783 0.575 2 PMID:7766669 -1.3.1.20 taurocholic acid bos taurus 0.07 0.07 1 PMID:7766669 -1.3.1.20 taurolithocholic acid bos taurus 0.217 0.14934999999999998 2 PMID:7766669 -1.3.1.20 trans-benzene dihydrodiol bos taurus 0.583 0.583 1 PMID:7766669 -1.3.1.20 trans-benzene dihydrodiol homo sapiens 0.145 0.0325 8 PMID:10634139;PMID:8573067;PMID:9578563 -1.3.1.20 trans-benzene dihydrodiol macaca fascicularis 24.6 24.6 1 PMID:15618685 -1.3.1.20 trans-benzene dihydrodiol macaca fuscata 14.0 14.0 1 PMID:2697716 -1.3.1.20 trans-benzene dihydrodiol macaca fuscata fuscata 90.0 90.0 1 PMID:15618685 -1.3.1.20 trans-naphthalene dihydrodiol bos taurus 0.65 0.65 1 PMID:7766669 -1.3.1.20 trans-naphthalene dihydrodiol macaca fuscata 34.0 34.0 1 PMID:2697716 -1.3.1.24 biliverdin homo sapiens 94.8 94.8 1 PMID:28169272 -1.3.1.24 biliverdin rattus norvegicus 69.3 69.3 1 PMID:28169272 -1.3.1.24 biliverdin synechocystis sp. pcc 6803 7.1 7.1 1 PMID:28169272 -1.3.1.24 nadh bos taurus 5.6 3.65 2 PMID:3191141 -1.3.1.24 nadph homo sapiens 0.237 0.20400000000000001 2 PMID:27897348 -1.3.1.27 2-nonenal homo sapiens 0.113 0.113 1 PMID:20835842 -1.3.1.27 3-buten-2-one homo sapiens 0.167 0.167 1 PMID:20835842 -1.3.1.27 4-hydroxy-2-hexenal homo sapiens 1.33 1.33 1 PMID:20835842 -1.3.1.27 4-hydroxy-2-nonenal homo sapiens 1.15 1.15 1 PMID:20835842 -1.3.1.28 (2s,3s)-2,3-dihydro-2,3-dihydroxybenzoate escherichia coli 25.3 25.3 1 PMID:2521622 -1.3.1.28 2-cyclohexen-1-ol escherichia coli 1.0 1.0 1 PMID:2144454 -1.3.1.28 cis-3,5-cyclohexadiene-1,2-diol escherichia coli 16.7 16.7 1 PMID:2144454 -1.3.1.28 cis-3-hydroxy-4-cyclohexene-1-carboxylate escherichia coli 23.0 23.0 1 PMID:2144454 -1.3.1.28 cis-3-hydroxycyclohexane-1-carboxylic acid escherichia coli 5.0 5.0 1 PMID:2144454 -1.3.1.28 methyl 2,3-dihydro-2,3-dihydroxybenzoate escherichia coli 17.5 17.5 1 PMID:2144454 -1.3.1.28 methyl-3-hydroxy-1,4-cyclohexadiene-1-carboxylate escherichia coli 3.0 3.0 1 PMID:2144454 -1.3.1.28 trans-2,3-dihydro-2,3-dihydroxy-benzoate escherichia coli 92.5 92.5 1 PMID:2144454 -1.3.1.28 trans-3,5-cyclohexadiene-1,2-diol escherichia coli 1.0 1.0 1 PMID:2144454 -1.3.1.28 trans-3-hydroxy-2-cyclohexene-1-carboxylate escherichia coli 5.0 5.0 1 PMID:2144454 -1.3.1.28 trans-3-hydroxycyclohexane-1-carboxylic acid escherichia coli 0.733 0.733 1 PMID:2144454 -1.3.1.29 (1r,2s)-1,2-dihydronaphthalene-1,2-diol pseudomonas putida 26.4 16.0 2 PMID:28089880 -1.3.1.29 3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl pseudomonas putida 0.1 0.1 1 PMID:10381363 -1.3.1.29 anthracene 1,2-dihydrodiol novosphingobium aromaticivorans 21.6 21.6 1 PMID:16820465 -1.3.1.29 benzo(a)anthracene 1,2-dihydrodiol novosphingobium aromaticivorans 9.1 9.1 1 PMID:16820465 -1.3.1.29 benzo(a)pyrene-9,10-dihydrodiol novosphingobium aromaticivorans 7.9 7.9 1 PMID:16820465 -1.3.1.29 biphenyl 2,3-dihydrodiol novosphingobium aromaticivorans 321.0 172.8 2 PMID:16820465 -1.3.1.29 chrysene 3,4-dihydrodiol novosphingobium aromaticivorans 218.0 119.15 2 PMID:16820465 -1.3.1.29 cis-1,2-dihydronaphthalene-1,2-diol pseudomonas putida 149.0 149.0 1 PMID:10381363 -1.3.1.29 cis-2,3-dihydro-2,3-dihydroxybiphenyl pseudomonas putida 51.7 51.7 1 PMID:10381363 -1.3.1.29 fluoranthene 2,3-dihydrodiol novosphingobium aromaticivorans 5.25 5.25 1 PMID:16820465 -1.3.1.29 nad+ pseudomonas putida 36.6 22.450000000000003 2 PMID:28089880 -1.3.1.29 naphthalene 1,2-dihydrodiol novosphingobium aromaticivorans 28.2 28.2 1 PMID:16820465 -1.3.1.29 phenanthrene 3,4-dihydrodiol novosphingobium aromaticivorans 16.7 16.7 1 PMID:16820465 -1.3.1.29 pyrene 4,5-dihydrodiol novosphingobium aromaticivorans 6.35 6.35 1 PMID:16820465 -1.3.1.3 1,4-androstadien-17beta-ol-3-one homo sapiens 0.035 0.035 1 PMID:21255593 -1.3.1.3 2-cyclohexen-1-one arabidopsis thaliana 1.11 1.11 1 PMID:22357344 -1.3.1.3 2-cyclohexen-1-one capsella rubella 0.23 0.23 1 PMID:32044030 -1.3.1.3 2-cyclohexen-1-one digitalis lanata 0.49 0.49 1 PMID:22357344 -1.3.1.3 4-androstene-3,17-dione homo sapiens 0.1 0.1 1 PMID:21255593 -1.3.1.3 4-androstene-3,17-dione mus musculus 0.09 0.07 2 PMID:30928400 -1.3.1.3 4-androstene-3,17-dione rattus norvegicus 0.0337 0.0337 1 PMID:6736016 -1.3.1.3 4-cholesten-7alpha-ol-3-one homo sapiens 0.033 0.033 1 PMID:21255593 -1.3.1.3 4-estren-17beta-ol-3-one homo sapiens 0.045 0.045 1 PMID:21255593 -1.3.1.3 7alpha,12alpha-dihydroxy-4-cholesten-3-one rattus norvegicus 0.0128 0.0128 1 PMID:6736016 -1.3.1.3 7alpha-hydroxy-4-cholesten-3-one rattus norvegicus 0.01 0.01 1 PMID:6736016 -1.3.1.3 aldosterone homo sapiens 0.15 0.15 1 PMID:21255593 -1.3.1.3 androstenedione homo sapiens 0.013 0.013 1 PMID:19075558 -1.3.1.3 cholestenone homo sapiens 0.01 0.01 1 PMID:21255593 -1.3.1.3 corticosterone homo sapiens 0.032 0.032 1 PMID:21255593 -1.3.1.3 cortisol homo sapiens 0.045 0.045 1 PMID:21255593 -1.3.1.3 cortisol mus musculus 0.13 0.10500000000000001 2 PMID:30928400 -1.3.1.3 cortisol rattus norvegicus 0.00817 0.00817 1 PMID:6736016 -1.3.1.3 cortisone homo sapiens 0.195 0.17 3 PMID:20522910;PMID:21255593 -1.3.1.3 cortisone rattus norvegicus 0.0375 0.0375 1 PMID:6736016 -1.3.1.3 epitestosterone homo sapiens 0.1 0.1 1 PMID:21255593 -1.3.1.3 progesterone arabidopsis thaliana 0.17 0.17 1 PMID:22357344 -1.3.1.3 progesterone bufo gargarizans 0.00197 0.00197 1 PMID:33548318 -1.3.1.3 progesterone digitalis lanata 0.019 0.019 1 PMID:22357344 -1.3.1.3 progesterone rattus norvegicus 1.8 0.9151 2 PMID:6736016;PMID:9657682 -1.3.1.3 testosterone homo sapiens 0.14 0.12 3 PMID:20522910;PMID:21255593 -1.3.1.3 testosterone rattus norvegicus 1.3 0.6604 2 PMID:6736016;PMID:9657682 -1.3.1.31 2-cyclohexen-1-one lacticaseibacillus casei 8400.0 8400.0 1 PMID:22579387 -1.3.1.31 2-methyl-n-phenylmaleimide achromobacter sp. 5.9 5.9 1 PMID:23644746 -1.3.1.31 nadh achromobacter sp. 38.6 38.6 1 PMID:23644746 -1.3.1.31 nadh bacillus subtilis 0.0153 0.0153 1 PMID:29155059 -1.3.1.31 nadh klebsiella pneumoniae 0.274 0.274 1 PMID:29155059 -1.3.1.31 nadh lacticaseibacillus casei 3200.0 3200.0 1 PMID:22579387 -1.3.1.31 nadph achromobacter sp. 19.2 19.2 1 PMID:23644746 -1.3.1.31 nadph bacillus subtilis 0.0168 0.0168 1 PMID:29155059 -1.3.1.31 nadph klebsiella pneumoniae 0.278 0.278 1 PMID:29155059 -1.3.1.31 nadph yersinia bercovieri 1.97 1.97 1 * -1.3.1.31 trans-cinnamic acid clostridium acetobutylicum 9.7 9.7 1 PMID:28616142 -1.3.1.31 trans-cinnamic acid heyndrickxia coagulans 1.1 1.1 1 PMID:28616142 -1.3.1.32 2-chloromaleylacetate sphingobium chlorophenolicum 17.6 17.6 2 PMID:29273747 -1.3.1.32 2-maleylacetate sphingobium chlorophenolicum 1.2 1.2 2 PMID:29273747 -1.3.1.32 maleylacetate pimelobacter simplex 114.0 114.0 1 PMID:10395975 -1.3.1.32 maleylacetate pseudomonas sp. 13.9 13.9 1 PMID:8407778 -1.3.1.32 maleylacetate sphingobium chlorophenolicum 1.2 1.2 1 PMID:19242755 -1.3.1.32 nadh sphingobium chlorophenolicum 143.7 72.44999999999999 4 PMID:29273747 -1.3.1.32 nadph sphingobium chlorophenolicum 29.7 15.2 4 PMID:29273747 -1.3.1.33 nadph chlamydomonas reinhardtii 0.043 0.043 1 PMID:26807652 -1.3.1.33 nadph cyanidioschyzon merolae 0.042 0.042 1 PMID:26807652 -1.3.1.33 nadph daucus carota 0.058 0.058 1 PMID:26807652 -1.3.1.33 nadph lyngbya majuscula 0.102 0.102 1 PMID:26807652 -1.3.1.33 nadph marchantia paleacea 0.019 0.019 1 PMID:26807652 -1.3.1.33 nadph nicotiana tabacum 0.017 0.017 1 PMID:26807652 -1.3.1.33 nadph nostoc punctiforme 0.035 0.035 1 PMID:26807652 -1.3.1.33 nadph physcomitrium patens 0.019 0.019 1 PMID:26807652 -1.3.1.33 nadph pinus mugo 0.02 0.02 1 PMID:26807652 -1.3.1.33 nadph thermosynechococcus vestitus 0.165 0.165 1 PMID:19850924 -1.3.1.33 nadph zea mays 0.026 0.026 1 PMID:26807652 -1.3.1.33 protochlorophyllide thermosynechococcus vestitus 0.17 0.165 5 PMID:19439417;PMID:19850924;PMID:27285815;PMID:32866986 -1.3.1.34 2-trans,4-trans-decadienoyl-coa escherichia coli 16.0 16.0 1 PMID:9346310 -1.3.1.34 nadph escherichia coli 9.5 9.5 1 PMID:18171025 -1.3.1.38 (4e)-dec-4-enoyl-coa mycobacterium tuberculosis 3.17 3.17 1 PMID:17472376 -1.3.1.42 2-cyclohexen-1-ol oryza sativa 10.22 9.58 5 PMID:21249367 -1.3.1.42 trans-hex-2-enal solanum lycopersicum 14.0 14.0 1 PMID:16983071 -1.3.1.44 2-dodecenoyl-coa treponema denticola 90.0 90.0 1 PMID:22906002 -1.3.1.44 crotonyl-coa treponema denticola 91.0 91.0 2 PMID:22906002 -1.3.1.44 hexanoyl-coa treponema denticola 112.0 112.0 1 PMID:22906002 -1.3.1.44 nadh clostridium acetobutylicum 28.2 28.2 2 PMID:23050861 -1.3.1.44 nadh treponema denticola 385.9 385.9 2 PMID:23050861 -1.3.1.44 trans-2-dodecenoyl-coa treponema denticola 90.0 90.0 1 PMID:22906002 -1.3.1.44 trans-2-hexenoyl-coa treponema denticola 112.0 112.0 1 PMID:22906002 -1.3.1.45 2'-hydroxyformononetin medicago sativa 0.215 0.215 1 PMID:16600295 -1.3.1.48 15-ketoprostaglandin e bos taurus 1.0 1.0 1 PMID:224937 -1.3.1.48 15-ketoprostaglandin e1 mus musculus 0.12 0.12 1 PMID:17449869 -1.3.1.48 15-ketoprostaglandin e1 rattus norvegicus 40.0 40.0 1 PMID:11524419 -1.3.1.48 15-ketoprostaglandin e1 sus scrofa 1.52 1.0185 2 * -1.3.1.48 15-ketoprostaglandin e2 mus musculus 0.19 0.19 1 PMID:17449869 -1.3.1.48 15-ketoprostaglandin f1alpha mus musculus 0.22 0.22 1 PMID:17449869 -1.3.1.48 15-ketoprostaglandin f2alpha mus musculus 0.25 0.25 1 PMID:17449869 -1.3.1.48 3-nonen-2-one rattus norvegicus 19.8 19.8 1 PMID:11524419 -1.3.1.48 3-penten-2-one rattus norvegicus 18.5 18.5 1 PMID:11524419 -1.3.1.48 4-hydroxy-2-hexenal rattus norvegicus 13.4 13.4 1 PMID:11524419 -1.3.1.48 4-hydroxy-2-nonenal rattus norvegicus 67.3 67.3 1 PMID:11524419 -1.3.1.48 acrolein rattus norvegicus 3.72 3.72 1 PMID:11524419 -1.3.1.48 alpha-methylcinnamaldehyde rattus norvegicus 13.1 13.1 1 PMID:11524419 -1.3.1.48 benzylidene acetone rattus norvegicus 54.7 54.7 1 PMID:11524419 -1.3.1.48 chalcone rattus norvegicus 32.3 32.3 1 PMID:11524419 -1.3.1.48 cinnamaldehyde rattus norvegicus 15.7 15.7 1 PMID:11524419 -1.3.1.48 crotonaldehyde rattus norvegicus 8.05 8.05 1 PMID:11524419 -1.3.1.48 ethylvinylketone rattus norvegicus 160.0 160.0 1 PMID:11524419 -1.3.1.48 methylvinylketone rattus norvegicus 156.0 156.0 1 PMID:11524419 -1.3.1.48 nadph mus musculus 0.16 0.16 1 PMID:17449869 -1.3.1.48 trans,trans-2,4-nonadienal rattus norvegicus 17.2 17.2 1 PMID:11524419 -1.3.1.48 trans-2-decenal rattus norvegicus 70.8 70.8 1 PMID:11524419 -1.3.1.48 trans-2-dodecenal rattus norvegicus 60.2 60.2 1 PMID:11524419 -1.3.1.48 trans-2-hexenal rattus norvegicus 28.8 28.8 1 PMID:11524419 -1.3.1.48 trans-2-nonenal rattus norvegicus 94.5 94.5 1 PMID:11524419 -1.3.1.48 trans-2-octenal rattus norvegicus 89.7 89.7 1 PMID:11524419 -1.3.1.48 trans-2-pentenal rattus norvegicus 16.8 16.8 1 PMID:11524419 -1.3.1.56 3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl comamonas testosteroni 0.123 0.123 1 PMID:10381363 -1.3.1.56 cis-1,2-dihydro-1,2-dihydroxynaphthalene comamonas testosteroni 0.9 0.9 1 PMID:10381363 -1.3.1.56 cis-2,3-dihydro-2,3-dihydroxybiphenyl comamonas testosteroni 0.38 0.38 1 PMID:10381363 -1.3.1.6 fumarate shewanella frigidimarina 658.0 439.5 4 PMID:12093271;PMID:14609326 -1.3.1.7 (+)-tartrate escherichia coli 0.417 0.417 1 PMID:7986065 -1.3.1.7 d-malate escherichia coli 13.3 13.3 1 PMID:7986065 -1.3.1.73 (r)-1,2-dihydrovomilenine rauvolfia serpentina 10.4 10.4 1 PMID:38212296 -1.3.1.73 vomilenine rauvolfia serpentina 0.2 0.2 1 PMID:38212296 -1.3.1.74 (2e)-hexenal arabidopsis thaliana 1.05 1.05 1 PMID:12514241 -1.3.1.74 (2e)-nonenal arabidopsis thaliana 0.85 0.85 1 PMID:12514241 -1.3.1.74 (2e)-pentenal arabidopsis thaliana 0.583 0.583 1 PMID:12514241 -1.3.1.74 (2e,6z)-nonadienal arabidopsis thaliana 33.9 33.9 1 PMID:16299173 -1.3.1.74 1-penten-3-one arabidopsis thaliana 4.0 4.0 1 PMID:21169366 -1.3.1.74 1-penten-3-one cucumis sativus 61.0 61.0 2 PMID:21169366 -1.3.1.74 13-oxo-(9e,11z)-octadecadienoic acid arabidopsis thaliana 1.1 1.1 1 PMID:16299173 -1.3.1.74 15-deoxy-delta12,14-prostaglandin j2 rattus norvegicus 0.308 0.308 1 PMID:16857669 -1.3.1.74 15-oxoprostaglandin e1 rattus norvegicus 40.0 40.0 1 PMID:11524419 -1.3.1.74 3-buten-2-one arabidopsis thaliana 3.5 2.44 2 PMID:12514241;PMID:21169366 -1.3.1.74 3-buten-2-one cucumis sativus 74.0 74.0 2 PMID:21169366 -1.3.1.74 3-nonen-2-one arabidopsis thaliana 18.9 18.9 1 PMID:16299173 -1.3.1.74 3-penten-2-one arabidopsis thaliana 1.72 1.72 1 PMID:12514241 -1.3.1.74 3-penten-2-one cucumis sativus 22.0 22.0 2 PMID:21169366 -1.3.1.74 4-hexen-3-one arabidopsis thaliana 3.3 3.3 1 PMID:21169366 -1.3.1.74 4-hexen-3-one cucumis sativus 68.0 68.0 2 PMID:21169366 -1.3.1.74 4-hydroxy-(2e)-hexenal arabidopsis thaliana 0.7 0.7 1 PMID:12514241 -1.3.1.74 4-hydroxy-(2e)-nonenal arabidopsis thaliana 88.1 50.0 3 PMID:12514241;PMID:16299173 -1.3.1.74 4-hydroxy-2-nonenal rattus norvegicus 66.7 66.7 1 PMID:11524419 -1.3.1.74 4-oxo-(2e)-nonenal arabidopsis thaliana 20.1 20.1 1 PMID:16299173 -1.3.1.74 9-oxo-(10e,12z)-octadecadienoic acid arabidopsis thaliana 0.94 0.94 1 PMID:16299173 -1.3.1.74 acrolein rattus norvegicus 3.67 3.67 1 PMID:11524419 -1.3.1.74 crotonaldehyde arabidopsis thaliana 1.3 1.3 1 PMID:21169366 -1.3.1.74 crotonaldehyde cucumis sativus 42.0 42.0 2 PMID:21169366 -1.3.1.74 diamide arabidopsis thaliana 1.58 1.58 1 PMID:12514241 -1.3.1.74 ethyl vinyl ketone rattus norvegicus 160.0 160.0 1 PMID:11524419 -1.3.1.74 nadh arabidopsis thaliana 23.0 23.0 1 PMID:21169366 -1.3.1.74 nadh cucumis sativus 75.0 75.0 2 PMID:21169366 -1.3.1.74 nadph arabidopsis thaliana 23.0 23.0 1 PMID:21169366 -1.3.1.74 nadph cucumis sativus 75.0 75.0 2 PMID:21169366 -1.3.1.74 propenal arabidopsis thaliana 22.0 11.3335 2 PMID:12514241;PMID:21169366 -1.3.1.74 propenal cucumis sativus 63.0 63.0 2 PMID:21169366 -1.3.1.74 trans-2-pentenal rattus norvegicus 16.83 8.899999999999999 2 PMID:16857669 -1.3.1.75 3,8-divinyl chlorophyllide a chlorobaculum tepidum 0.66 0.66 1 PMID:32180325 -1.3.1.75 3,8-divinyl chlorophyllide a rhodobacter capsulatus 0.66 0.0074 3 * -1.3.1.75 3,8-divinyl protochlorophyllide a rhodobacter capsulatus 0.66 0.0074 3 * -1.3.1.75 8-vinyl chlorophyllide a rhodobacter capsulatus 0.66 0.66 1 PMID:32180325 -1.3.1.77 cyanidin arabidopsis thaliana 1.045 1.045 1 PMID:14725861 -1.3.1.77 cyanidin camellia sinensis 0.0028 0.002 2 PMID:23288883 -1.3.1.77 cyanidin mangifera indica 42.37 37.334999999999994 2 PMID:30400564 -1.3.1.77 cyanidin medicago truncatula 0.18 0.18 1 PMID:14725861 -1.3.1.77 cyanidin vitis bellula 1.665 1.665 1 PMID:24880552 -1.3.1.77 delphinidin arabidopsis thaliana 0.058 0.058 1 PMID:14725861 -1.3.1.77 delphinidin camellia sinensis 0.0026 0.0018999999999999998 2 PMID:23288883 -1.3.1.77 delphinidin medicago truncatula 1.34 1.34 1 PMID:14725861 -1.3.1.77 delphinidin vitis bellula 2.012 2.012 1 PMID:24880552 -1.3.1.77 pelargonidin vitis bellula 2.0 2.0 1 PMID:24880552 -1.3.1.78 arogenate arabidopsis thaliana 84.2 84.2 1 PMID:12354106 -1.3.1.78 l-arogenate arabidopsis thaliana 37.3 37.3 1 PMID:12354106 -1.3.1.78 prephenate arabidopsis thaliana 3.4 3.4 1 PMID:12354106 -1.3.1.79 l-arogenate sediminispirochaeta smaragdinae 3.44 3.44 1 PMID:29164132 -1.3.1.81 (+)-pulegone mentha x piperita 1.8 1.8 1 PMID:13679086 -1.3.1.81 nadph mentha x piperita 1.8 1.8 1 PMID:13679086 -1.3.1.82 (-)-isopiperitenone mentha x piperita 1.3 1.3 1 PMID:13679086 -1.3.1.82 nadph mentha x piperita 1.3 1.3 1 PMID:13679086 -1.3.1.84 acrylyl-coa cereibacter sphaeroides 80.0 80.0 1 PMID:23955006 -1.3.1.84 acrylyl-coa escherichia coli 45.0 45.0 1 PMID:23955006 -1.3.1.84 acrylyl-coa ruegeria pomeroyi 60.0 60.0 1 PMID:23955006 -1.3.1.84 nadph sulfurisphaera tokodaii 13.0 13.0 1 PMID:19429610 -1.3.1.85 (2s)-ethylmalonyl-coa cereibacter sphaeroides 2.4.1 104.0 104.0 1 PMID:17548827 -1.3.1.85 cinnamoyl-coa streptomyces sp. 0.0688 0.0688 1 PMID:26356484 -1.3.1.85 co2 kitasatospora setae 78.0 78.0 1 PMID:31243147 -1.3.1.85 crotonyl-coa kitasatospora setae 103.0 103.0 1 PMID:31243147 -1.3.1.85 crotonyl-coa streptomyces sp. 0.1755 0.1755 1 PMID:26356484 -1.3.1.85 nadph kitasatospora setae 86.0 86.0 1 PMID:31243147 -1.3.1.86 butyryl-coa clostridioides difficile 8.0 8.0 1 PMID:23772070 -1.3.1.86 crotonyl-coa clostridioides difficile 19.0 19.0 1 PMID:23772070 -1.3.1.86 ferredoxin clostridioides difficile 37.0 37.0 1 PMID:23772070 -1.3.1.86 nadh clostridioides difficile 6.0 6.0 1 PMID:23772070 -1.3.1.9 (2e)-2-dodecenoyl-coa burkholderia mallei 28.8 28.8 1 PMID:20055482 -1.3.1.9 crotonoyl-coa uncultured bacterium 100.0 100.0 1 PMID:32112503 -1.3.1.9 crotonyl coa escherichia coli 0.00278 0.00278 1 PMID:10493822 -1.3.1.9 crotonyl-[acyl-carrier-protein] burkholderia pseudomallei 4.0 4.0 1 PMID:21393229 -1.3.1.9 crotonyl-coa burkholderia pseudomallei 3.6 3.6 1 PMID:21393229 -1.3.1.9 crotonyl-coa escherichia coli 5.3 5.3 1 PMID:25527535 -1.3.1.9 crotonyl-coa plasmodium falciparum 6.2 6.2 1 PMID:21603269 -1.3.1.9 crotonyl-coa xanthomonas oryzae 22.25 22.25 1 PMID:22039545 -1.3.1.9 nadh mycobacterium tuberculosis 17.0 8.35 3 PMID:10869170;PMID:28680153;PMID:30217823 -1.3.1.9 nadh uncultured bacterium 38.0 38.0 1 PMID:32112503 -1.3.1.9 octenoyl-coa mycobacterium tuberculosis 3.6 3.6 1 PMID:30217823 -1.3.1.9 trans-2-decenoyl-coa burkholderia pseudomallei 5.6 5.6 1 PMID:21393229 -1.3.1.9 trans-2-decenoyl-coa yersinia pestis 5.53 5.53 1 PMID:27136302 -1.3.1.9 trans-2-dodecenoyl-coa burkholderia pseudomallei 8.4 8.4 1 PMID:21393229 -1.3.1.9 trans-2-dodecenoyl-coa escherichia coli 11.9 11.9 1 PMID:12693936 -1.3.1.9 trans-2-dodecenoyl-coa mycobacterium tuberculosis 11.6 8.35 3 PMID:10869170;PMID:21143326;PMID:28680153 -1.3.1.9 trans-2-dodecenoyl-coa yersinia pestis 91.13 91.13 1 PMID:27136302 -1.3.1.9 trans-2-octenoyl-[acyl-carrier protein] yersinia pestis 14.92 14.92 1 PMID:27136302 -1.3.1.9 trans-2-octenoyl-coa burkholderia pseudomallei 28.3 28.3 1 PMID:21393229 -1.3.1.9 trans-2-octenoyl-coa yersinia pestis 0.27 0.27 1 PMID:27136302 -1.3.1.9 trans-but-2-enoyl-[acyl-carrier protein] cereibacter sphaeroides 0.65 0.65 1 PMID:12459184 -1.3.1.9 trans-but-2-enoyl-[acyl-carrier protein] plasmodium falciparum 1.62 1.62 1 PMID:15139852 -1.3.1.9 trans-but-2-enoyl-[acyl-carrier protein] streptococcus pneumoniae 70.0 35.008 2 PMID:12487627 -1.3.1.92 (+)-carvone artemisia annua 0.86 0.86 1 PMID:18495659 -1.3.1.92 2-cyclohexen-1-one artemisia annua 1.8 1.8 1 PMID:18495659 -1.3.1.92 artemisinic aldehyde artemisia annua 2.6 2.6 1 PMID:18495659 -1.3.1.92 nadh artemisia annua 1.3 1.3 1 PMID:18495659 -1.3.1.92 nadph artemisia annua 2.5 2.5 1 PMID:18495659 -1.3.1.95 3-buten-2-one anaerotignum propionicum 29.0 29.0 1 PMID:12603323 -1.3.1.95 acryloyl-coa anaerotignum propionicum 4.5 4.5 1 PMID:12603323 -1.3.1.95 acryloyl-coa metallosphaera sedula 13.0 13.0 1 PMID:19429610 -1.3.1.95 acryloyl-coa sulfurisphaera tokodaii 13.0 13.0 1 PMID:19429610 -1.3.1.95 nadh anaerotignum propionicum 3.5 3.5 1 PMID:12603323 -1.3.2.3 1,4-benzoquinone arabidopsis thaliana 108.0 108.0 1 PMID:18190525 -1.3.2.3 cytochrome c arabidopsis thaliana 151.0 151.0 1 PMID:18190525 -1.3.2.3 d-arabinono-1,4-lactone arabidopsis thaliana 51.0 51.0 1 PMID:19737562 -1.3.2.3 l-galactono-1,4-lactone arabidopsis thaliana 134.0 134.0 3 PMID:18190525;PMID:19369590;PMID:19737562 -1.3.2.3 l-gulono-1,4-lactone arabidopsis thaliana 4.0 4.0 2 PMID:18190525;PMID:19737562 -1.3.2.3 phenazine methosulfate arabidopsis thaliana 64.0 64.0 1 PMID:18190525 -1.3.2.4 fumarate shewanella frigidimarina 658.0 509.0 14 PMID:10079073;PMID:10978153;PMID:11004445;PMID:12356299;PMID:14609326 -1.3.2.4 fumarate shewanella putrefaciens 250.0 250.0 1 PMID:8093012 -1.3.2.4 succinate shewanella frigidimarina 1.36 0.715 6 PMID:10079073 -1.3.2.4 succinate shewanella putrefaciens 0.07 0.07 1 PMID:8093012 -1.3.3.10 adrenocorticotropic hormone chromobacterium violaceum 0.283 0.283 1 PMID:7559518 -1.3.3.10 indole-3-propionate chromobacterium violaceum 0.785 0.785 1 PMID:7559518 -1.3.3.10 l-tryptophan chromobacterium violaceum 0.66 0.66 1 PMID:7559518 -1.3.3.10 l-tryptophanamide chromobacterium violaceum 0.593 0.593 1 PMID:7559518 -1.3.3.10 luteinizing hormone-releasing hormone chromobacterium violaceum 0.333 0.333 1 PMID:7559518 -1.3.3.10 n-acetyl-l-tryptophan chromobacterium violaceum 0.79 0.79 1 PMID:7559518 -1.3.3.10 n-acetyl-l-tryptophanamide chromobacterium violaceum 0.753 0.753 1 PMID:7559518;PMID:8027079 -1.3.3.10 pentagastrin chromobacterium violaceum 0.533 0.533 1 PMID:7559518 -1.3.3.12 d-arabinono-1,4-lactone trypanosoma cruzi 0.285 0.285 1 PMID:17627608 -1.3.3.12 l-galactono-1,4-lactone trypanosoma cruzi 0.161 0.161 1 PMID:17627608 -1.3.3.13 cyclo(l-leu-l-phe) streptomyces noursei 0.69 0.69 1 PMID:11248691 -1.3.3.13 cyclo(l-phe-l-his) streptomyces noursei 0.453 0.453 1 PMID:11248691 -1.3.3.15 coproporphyrinogen iii staphylococcus aureus 0.46 0.46 1 PMID:27597779 -1.3.3.15 protoporphyrinogen ix halothece sp. pcc 7418 0.256 0.256 1 PMID:31621006 -1.3.3.15 protoporphyrinogen ix phormidium nigroviride 0.252 0.252 1 PMID:31621006 -1.3.3.15 protoporphyrinogen ix staphylococcus aureus 0.44 0.44 1 PMID:27597779 -1.3.3.17 benzylmalonyl-coa aromatoleum aromaticum 3.5 3.5 1 PMID:34059946 -1.3.3.3 3-[7,13-di(2-carboxy-ethyl)-17-ethyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid homo sapiens 0.0017 0.0017 1 PMID:18160932 -1.3.3.3 3-[7,17-di(2-carboxy-ethyl)-13-ethyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid homo sapiens 0.0283 0.0283 1 PMID:18160932 -1.3.3.3 3-[7-(2-carboxy-ethyl)-13,17-dibutyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid homo sapiens 6e-06 6e-06 1 PMID:18160932 -1.3.3.3 3-[7-(2-carboxy-ethyl)-13,17-diethyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid homo sapiens 0.0063 0.0063 1 PMID:18160932 -1.3.3.3 3-[7-(2-carboxy-ethyl)-13,17-dipropyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid homo sapiens 0.000165 0.000165 1 PMID:18160932 -1.3.3.3 coproporphyrinogen iii homo sapiens 0.017 0.017 1 PMID:16084099 -1.3.3.3 coproporphyrinogen-iii escherichia coli 0.003 0.003 1 PMID:12975365 -1.3.3.3 coproporphyrinogen-iii homo sapiens 16.0 0.05 12 PMID:16084099;PMID:16258391;PMID:17179900;PMID:17242372;PMID:18160932;PMID:19339664;PMID:8955072 -1.3.3.3 coproporphyrinogen-iv homo sapiens 0.043 0.0283 3 PMID:16258391 -1.3.3.3 harderoporphyrinogen homo sapiens 0.1317 0.1317 1 PMID:17179900 -1.3.3.3 mesoporphyrinogen-vi homo sapiens 0.0063 0.0063 1 PMID:17242372 -1.3.3.3 pentacarboxylate porphyrinogen 5dab homo sapiens 0.009 0.009 2 PMID:16084099 -1.3.3.4 coproporphyrinogen-iii bacillus subtilis 0.000833 0.000833 1 PMID:9784236 -1.3.3.4 mesoporphyrinogen-ix bacillus subtilis 0.0448 0.0448 1 PMID:9784236 -1.3.3.4 protoporphyrinogen ix arabidopsis thaliana 0.117 0.117 1 PMID:31621006 -1.3.3.4 protoporphyrinogen ix bacillus subtilis 0.0131 0.00825 2 PMID:19266155;PMID:19944166 -1.3.3.4 protoporphyrinogen ix homo sapiens 0.192 0.121 2 PMID:23935953;PMID:33857841 -1.3.3.4 protoporphyrinogen ix myxococcus xanthus 0.72 0.72 1 PMID:29124218 -1.3.3.4 protoporphyrinogen ix nicotiana tabacum 6.0 6.0 1 PMID:23935953 -1.3.3.4 protoporphyrinogen-ix bacillus subtilis 14.1 0.00317 3 PMID:12941291;PMID:9784236 -1.3.3.4 protoporphyrinogen-ix homo sapiens 5.95 3.0625 2 PMID:12922165;PMID:8673113 -1.3.3.4 protoporphyrinogen-ix megalodesulfovibrio gigas 0.295 0.295 1 PMID:3667528 -1.3.3.4 protoporphyrinogen-ix mus musculus 0.124 0.124 1 PMID:2451512 -1.3.3.4 protoporphyrinogen-ix myxococcus xanthus 0.0867 0.0867 1 PMID:8621504 -1.3.3.4 protoporphyrinogen-ix nicotiana tabacum 597.0 37.0 13 PMID:17134376 -1.3.3.5 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) bacillus pumilus 716.0 391.0 3 PMID:27165502 -1.3.3.5 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) thermosediminibacter oceani 130.9 130.9 1 * -1.3.3.5 2,2'-azino-bis(3-ethylbenzthioline-6-sulfonic acid) albifimbria verrucaria 7.17 7.17 1 PMID:8597577 -1.3.3.5 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) albifimbria verrucaria 164.0 139.5 2 PMID:15802224 -1.3.3.5 2,6-dimethoxyphenol bacillus pumilus 100.0 57.0 3 PMID:27165502 -1.3.3.5 bilirubin albifimbria verrucaria 583.0 117.0 9 PMID:15802224;PMID:18553870;PMID:18609637;PMID:22862914;PMID:22878843 -1.3.3.5 bilirubin aspergillus oryzae 3.93 3.93 1 PMID:16305950 -1.3.3.5 bilirubin bacillus pumilus 70.0 68.5 4 PMID:22410485;PMID:22878843 -1.3.3.5 bilirubin pyricularia oryzae 29.0 29.0 1 PMID:22878843 -1.3.3.5 bilirubin thermosediminibacter oceani 76.2 76.2 1 * -1.3.3.5 biliverdin albifimbria verrucaria 20.0 20.0 1 PMID:18553870 -1.3.3.5 ditaurobilirubin albifimbria verrucaria 233.0 163.65 2 PMID:15802224 -1.3.3.5 k4[fe(cn)6] albifimbria verrucaria 374.0 374.0 1 * -1.3.3.5 p-phenylenediamine albifimbria verrucaria 90.0 75.0 2 PMID:15802224 -1.3.3.5 syringaldazine albifimbria verrucaria 2.08 1.04665 2 PMID:8597577 -1.3.3.5 syringaldazine thermosediminibacter oceani 72.5 72.5 1 * -1.3.3.6 butyryl-coa glutamicibacter nicotianae 0.225 0.225 1 * -1.3.3.6 cis-3-decenoyl-coa rattus norvegicus 0.06167 0.06167 1 PMID:16236453 -1.3.3.6 cis-3-hexenoyl-coa rattus norvegicus 0.35 0.35 1 PMID:16236453 -1.3.3.6 cis-3-octenoyl-coa rattus norvegicus 0.075 0.075 1 PMID:16236453 -1.3.3.6 decanoyl-coa yarrowia lipolytica 1.53 1.53 1 PMID:11147819 -1.3.3.6 hexanoyl-coa glutamicibacter nicotianae 0.203 0.203 1 * -1.3.3.6 hexanoyl-coa rattus norvegicus 0.089 0.089 1 PMID:18061544 -1.3.3.6 hexanoyl-coa yarrowia lipolytica 8.59 8.59 1 PMID:11147819 -1.3.3.6 octanoyl-coa glutamicibacter nicotianae 0.07 0.07 1 * -1.3.3.6 octanoyl-coa rattus norvegicus 3.47 3.47 2 PMID:15477094;PMID:29372418 -1.3.3.6 palmitoyl-coa paenarthrobacter ureafaciens 78.0 78.0 1 PMID:17141592 -1.3.3.6 trans-3-decenoyl-coa rattus norvegicus 0.01567 0.01567 1 PMID:16236453 -1.3.3.6 trans-3-hexenoyl-coa rattus norvegicus 0.05 0.05 1 PMID:16236453 -1.3.3.6 trans-3-octenoyl-coa rattus norvegicus 0.045 0.045 1 PMID:16236453 -1.3.5.1 1,4-naphthoquinone thermus thermophilus 3.67 3.67 1 PMID:20951673 -1.3.5.1 2,3-dimethoxy-5-methyl-1,4-benzoquinone escherichia coli 182.0 108.5 2 PMID:3511050 -1.3.5.1 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone saccharomyces cerevisiae 60.0 31.8 2 PMID:11279023;PMID:14672930 -1.3.5.1 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-2h-tetrazolium bromide escherichia coli 20.9 20.9 1 PMID:18690748 -1.3.5.1 d-malate bos taurus 0.283 0.283 1 PMID:2624174 -1.3.5.1 duroquinone thermus thermophilus 2.167 2.167 1 PMID:20951673 -1.3.5.1 ferricyanide escherichia coli 28.7 28.7 1 PMID:23836905 -1.3.5.1 fumarate escherichia coli 250.0 203.5 4 PMID:11803023;PMID:16484232;PMID:16829675 -1.3.5.1 fumarate rhodothermus marinus 79.6 79.6 1 PMID:11710809 -1.3.5.1 fumarate wolinella succinogenes 133.0 76.5 2 PMID:7333282 -1.3.5.1 l-malate bos taurus 0.142 0.142 1 PMID:2624174 -1.3.5.1 menadione thermus thermophilus 1.67 1.67 1 PMID:20951673 -1.3.5.1 menaquinol escherichia coli 222.2 216.6 2 PMID:23836905 -1.3.5.1 naphthoquinol paracoccus denitrificans 2.0 2.0 1 PMID:9639600 -1.3.5.1 oxidized 2,6-dichlorophenolindophenol thermus thermophilus 1.83 1.83 1 PMID:20951673 -1.3.5.1 oxidized phenazine ethosulfate escherichia coli 82.0 82.0 1 PMID:11259408 -1.3.5.1 phenazine methosulfate bacillus cereus 77.0 77.0 1 PMID:18535631 -1.3.5.1 phenazine methosulfate thermus thermophilus 8.33 8.33 1 PMID:20951673 -1.3.5.1 reduced plumbagin escherichia coli 15.9 15.9 1 PMID:18690748 -1.3.5.1 succinate bos taurus 217.0 150.0 3 PMID:2624174;PMID:2994719;PMID:383238;PMID:4326770;PMID:713837 -1.3.5.1 succinate escherichia coli 217.0 54.0 8 PMID:11259408;PMID:11803023;PMID:11803025;PMID:16484232;PMID:16829675;PMID:383238;PMID:4326770;PMID:713837 -1.3.5.1 succinate mammalia 217.0 217.0 1 PMID:383238;PMID:4326770;PMID:713837 -1.3.5.1 succinate mycolicibacterium smegmatis 3.16 3.16 1 PMID:32843629 -1.3.5.1 succinate paracoccus denitrificans 260.0 260.0 1 PMID:9639600 -1.3.5.1 succinate rhodospirillum rubrum 66.7 66.7 1 PMID:4344128 -1.3.5.1 succinate rhodothermus marinus 80.0 80.0 1 PMID:15796920 -1.3.5.1 succinate wolinella succinogenes 13.0 13.0 1 * -1.3.5.1 ubiquinone escherichia coli 37.9 31.4 2 PMID:18690748;PMID:23836905 -1.3.5.2 (s)-dihydroorotate drosophila melanogaster 7.5 7.5 1 PMID:12213251 -1.3.5.2 (s)-dihydroorotate phytophthora infestans 75.0 75.0 1 PMID:31316493 -1.3.5.2 (s)-dihydroorotate solanum tuberosum 30.0 30.0 1 PMID:31316493 -1.3.5.2 (s)-dihydroorotate toxoplasma gondii 86.0 86.0 3 PMID:22580100;PMID:23747278 -1.3.5.2 1,4-naphthoquinone toxoplasma gondii 29.0 29.0 1 PMID:22580100 -1.3.5.2 2,3-dimethoxy-5-methyl-1,4-benzoquinone toxoplasma gondii 32.0 32.0 1 PMID:22580100 -1.3.5.2 2,5-dimethyl-p-benzoquinone toxoplasma gondii 44.0 44.0 1 PMID:22580100 -1.3.5.2 coenzyme q1 plasmodium falciparum 7.8 7.8 1 PMID:18225919 -1.3.5.2 coenzyme q6 bos taurus 44.2 44.2 1 PMID:2540819 -1.3.5.2 coenzyme qd plasmodium falciparum 12.0 12.0 1 PMID:18225919 -1.3.5.2 decylubiquinone plasmodium falciparum 1.8 1.8 1 PMID:12189151 -1.3.5.2 decylubiquinone toxoplasma gondii 89.0 87.5 2 PMID:22580100;PMID:23747278 -1.3.5.2 dihydroorotate arabidopsis thaliana 8.2 8.2 1 PMID:12372626 -1.3.5.2 dihydroorotate bos taurus 50.4 50.4 1 PMID:2540819 -1.3.5.2 dihydroorotate candida albicans 2.2 2.1500000000000004 2 PMID:16774642 -1.3.5.2 dihydroorotate homo sapiens 0.78 0.78 1 PMID:30664899 -1.3.5.2 dihydroorotate plasmodium falciparum 15.8 15.8 1 PMID:17228860 -1.3.5.2 l-dihydroorotate plasmodium falciparum 15.8 2.0 7 PMID:12189151;PMID:15795226;PMID:17228860 -1.3.5.2 menadione bos taurus 18.3 18.3 1 PMID:2540819 -1.3.5.2 methyl-dihydroorotate bos taurus 45.4 45.4 1 PMID:2540819 -1.3.5.2 o2 plasmodium falciparum 0.42 0.42 1 PMID:18225919 -1.3.5.2 s-dihydroorotate escherichia coli 19.7 19.7 1 PMID:11284694 -1.3.5.2 s-dihydroorotate homo sapiens 75.0 75.0 1 PMID:11248707 -1.3.5.2 s-dihydroorotate mus musculus 71.0 71.0 1 PMID:11248707 -1.3.5.2 s-dihydroorotate plasmodium falciparum 0.25 0.25 1 PMID:7727509 -1.3.5.2 s-dihydroorotate rattus norvegicus 95.0 95.0 1 PMID:11248707 -1.3.5.2 ubiquinone-30 toxoplasma gondii 21.0 21.0 1 PMID:22580100 -1.3.5.2 ubiquinone-4 plasmodium falciparum 1.8 1.8 1 PMID:12189151 -1.3.5.2 ubiquinone-50 toxoplasma gondii 61.0 61.0 1 PMID:22580100 -1.3.5.2 ubiquinone-6 plasmodium falciparum 2.0 2.0 1 PMID:12189151 -1.3.5.2 ubiquinone6 plasmodium falciparum 0.36 0.36 1 PMID:7727509 -1.3.5.3 menadione escherichia coli 0.281 0.281 1 PMID:19583219 -1.3.5.3 protoporphyrinogen ix escherichia coli 0.292 0.292 1 PMID:19583219 -1.3.7.11 geranylgeranyl diphosphate sulfolobus acidocaldarius 0.0067 0.0067 1 PMID:24954619 -1.3.7.15 8-vinyl chlorophyllide a rhodobacter capsulatus 0.011 0.005634999999999999 2 PMID:32180325 -1.3.7.4 biliverdin ixa avena sativa 1.67 1.67 1 PMID:11500553 -1.3.8.1 2-methylbutanoyl-coa homo sapiens 6.0 6.0 1 PMID:12220177 -1.3.8.1 butanoyl-coa clostridioides difficile 8.0 8.0 1 PMID:23772070 -1.3.8.1 butanoyl-coa homo sapiens 9.6 9.6 1 PMID:12220177 -1.3.8.1 butyryl-coa bos taurus 33.3 17.9 2 PMID:13130521;PMID:4062874 -1.3.8.1 butyryl-coa clostridioides difficile 8.0 8.0 1 PMID:23772070 -1.3.8.1 butyryl-coa homo sapiens 20.8 20.8 1 PMID:3597357 -1.3.8.1 butyryl-coa megasphaera elsdenii 20.8 5.0 7 PMID:6466635;PMID:6712628;PMID:9671517 -1.3.8.1 butyryl-coa pseudomonas putida 1.743 0.73 7 PMID:16024185 -1.3.8.1 butyryl-coa sus scrofa 9.17 6.835 2 * -1.3.8.1 crotonyl-coa clostridioides difficile 19.0 19.0 2 PMID:23772070 -1.3.8.1 heptanoyl-coa bos taurus 0.25 0.25 1 PMID:4062874 -1.3.8.1 heptanoyl-coa pseudomonas putida 0.00567 0.00567 1 PMID:16024185 -1.3.8.1 hexanoyl-coa bos taurus 1.35 1.35 1 PMID:4062874 -1.3.8.1 hexanoyl-coa homo sapiens 16.5 13.25 2 PMID:12220177;PMID:3597357 -1.3.8.1 hexanoyl-coa pseudomonas putida 0.2992 0.2992 1 PMID:16024185 -1.3.8.1 nadh clostridioides difficile 6.0 6.0 1 PMID:23772070 -1.3.8.1 octanoyl-coa bos taurus 0.1 0.1 1 PMID:4062874 -1.3.8.1 octanoyl-coa pseudomonas putida 0.00183 0.00183 1 PMID:16024185 -1.3.8.1 pentanoyl-coa bos taurus 3.3 3.3 1 PMID:4062874 -1.3.8.1 pentanoyl-coa rattus norvegicus 24.5 13.75 2 PMID:3968064 -1.3.8.1 propionyl-coa bos taurus 0.03 0.03 1 PMID:4062874 -1.3.8.1 propionyl-coa megasphaera elsdenii 0.0333 0.0333 1 PMID:7159554 -1.3.8.1 reduced ferredoxin clostridioides difficile 37.0 37.0 1 PMID:23772070 -1.3.8.1 valeryl-coa homo sapiens 40.7 40.7 1 PMID:3597357 -1.3.8.1 valeryl-coa pseudomonas putida 2.403 2.403 1 PMID:16024185 -1.3.8.12 (2s)-methylsuccinyl-coa paracoccus denitrificans 82.3 82.3 2 PMID:29275330 -1.3.8.12 succinyl-coa paracoccus denitrificans 0.32 0.32 2 PMID:29275330 -1.3.8.16 2-amino-2-deoxyisochorismate streptomyces globisporus 15.0 15.0 1 PMID:18182490 -1.3.8.16 fmn streptomyces globisporus 17.0 17.0 1 PMID:18182490 -1.3.8.4 butyryl-coa caenorhabditis elegans 0.133 0.133 1 PMID:11386848 -1.3.8.4 hexanoyl-coa caenorhabditis elegans 0.533 0.533 1 PMID:11386848 -1.3.8.4 isovaleryl-coa caenorhabditis elegans 2.37 2.37 1 PMID:11386848 -1.3.8.4 isovaleryl-coa homo sapiens 10.0 9.4 2 PMID:9665741 -1.3.8.4 isovaleryl-coa rattus norvegicus 1.5 0.91 2 PMID:23474214 -1.3.8.4 isovaleryl-coa solanum tuberosum 0.98 0.98 1 PMID:15574432 -1.3.8.4 valeryl-coa caenorhabditis elegans 0.267 0.267 1 PMID:11386848 -1.3.8.5 (s)-2-methylbutanoyl-coa homo sapiens 9700.0 9700.0 1 PMID:12855692 -1.3.8.5 (s)-2-methylbutanoyl-coa rattus norvegicus 3000.0 3000.0 1 PMID:12855692 -1.3.8.5 2-methylbutanoyl-coa solanum tuberosum 1.77 1.77 1 PMID:15574432 -1.3.8.5 hexanoyl-coa homo sapiens 7600.0 7600.0 1 PMID:12855692 -1.3.8.5 hexanoyl-coa rattus norvegicus 1800.0 1800.0 1 PMID:12855692 -1.3.8.5 isobutyryl-coa homo sapiens 2900.0 2900.0 1 PMID:12855692 -1.3.8.5 isobutyryl-coa rattus norvegicus 8500.0 8500.0 1 PMID:12855692 -1.3.8.6 4-nitrobutyryl-coa homo sapiens 0.033 0.033 1 PMID:11802727 -1.3.8.6 dichlorophenolindophenol homo sapiens 4.8 4.8 1 PMID:10985795 -1.3.8.6 electron-transfer flavoprotein homo sapiens 5.7 5.7 1 PMID:10985795 -1.3.8.6 electron-transfer flavoprotein paracoccus denitrificans 16.0 16.0 1 PMID:2991202 -1.3.8.6 electron-transfer flavoprotein sus scrofa 14.3 14.3 1 PMID:3081514 -1.3.8.6 ferrocenium hexafluorophosphate homo sapiens 7.5 7.5 1 PMID:10985795 -1.3.8.6 glutaryl-coa homo sapiens 13.2 5.6 8 PMID:11802727;PMID:12948740;PMID:16229482;PMID:17176108;PMID:18020372;PMID:31491587 -1.3.8.6 glutaryl-coa rattus norvegicus 0.004 0.004 1 PMID:21974953 -1.3.8.6 glutaryl-coa sus scrofa 5.45 5.45 1 PMID:3081514 -1.3.8.6 human electron-transfer flavoprotein homo sapiens 3.1 3.1 1 PMID:8541831 -1.3.8.6 phenazine methosulfate homo sapiens 4.8 4.8 1 PMID:10985795 -1.3.8.6 phenylmethylsulfonyl fluoride paracoccus denitrificans 16.0 16.0 1 PMID:2991202 -1.3.8.7 [4-(dimethylamino)phenyl]propionyl-coa homo sapiens 4.6 4.6 1 PMID:7578106 -1.3.8.7 [4-(dimethylamino)phenyl]propionyl-coa sus scrofa 0.61 0.61 1 PMID:7578106 -1.3.8.7 butanoyl-coa homo sapiens 11.5 11.5 1 PMID:7578106 -1.3.8.7 butanoyl-coa sus scrofa 6.33 6.265000000000001 2 PMID:7578106;PMID:9208949 -1.3.8.7 crotonyl-coa sus scrofa 0.00783 0.00783 1 PMID:3756134 -1.3.8.7 decanoyl-coa homo sapiens 11.7 9.67 3 PMID:7578106;PMID:8823175;PMID:9182995 -1.3.8.7 decanoyl-coa sus scrofa 8.6 8.6 1 PMID:7578106 -1.3.8.7 dodecanoyl-coa homo sapiens 9.17 8.085 2 PMID:8823175;PMID:9182995 -1.3.8.7 electron transfer flavoprotein sus scrofa 11.6 11.6 1 PMID:7317051 -1.3.8.7 electron transferring flavoprotein bos taurus 2.0 2.0 1 PMID:1015826 -1.3.8.7 electron transferring flavoprotein sus scrofa 2.33 2.33 1 PMID:2363500 -1.3.8.7 electron-transfer flavoprotein sus scrofa 12.0 12.0 1 PMID:6863254 -1.3.8.7 ferricenium hexafluorophosphate sus scrofa 18.3 18.3 1 PMID:2363500 -1.3.8.7 furylpropionyl-coa homo sapiens 13.6 13.6 1 PMID:7578106 -1.3.8.7 furylpropionyl-coa sus scrofa 13.2 13.2 1 PMID:7578106 -1.3.8.7 hexadecanoyl-coa homo sapiens 2.33 2.33 1 PMID:8823175 -1.3.8.7 hexanoyl-coa homo sapiens 16.8 15.5 2 PMID:7578106;PMID:8823175 -1.3.8.7 hexanoyl-coa rattus norvegicus 31.2 31.2 1 PMID:3968063 -1.3.8.7 hexanoyl-coa sus scrofa 20.8 20.700000000000003 2 PMID:7578106;PMID:9208949 -1.3.8.7 indolepropionyl-coa homo sapiens 3.4 3.4 1 PMID:7578106 -1.3.8.7 indolepropionyl-coa sus scrofa 0.46 0.23800000000000002 2 PMID:7578106 -1.3.8.7 meldola's blue sus scrofa 0.1 0.1 1 PMID:2363500 -1.3.8.7 octanoyl-coa homo sapiens 19.2 17.0 3 PMID:11926826;PMID:7578106;PMID:8823175 -1.3.8.7 octanoyl-coa rattus norvegicus 35.7 3.3 5 PMID:15358373;PMID:16365837;PMID:18061544;PMID:3968064 -1.3.8.7 octanoyl-coa sus scrofa 33.3 14.75 10 PMID:1168197;PMID:14529297;PMID:570409;PMID:7278659;PMID:7278660;PMID:7440536;PMID:9208949 -1.3.8.7 octanoyl-pantetheine sus scrofa 0.235 0.235 1 PMID:7440536 -1.3.8.7 phenazine ethosulfate sus scrofa 0.75 0.75 1 PMID:2363500 -1.3.8.7 phenazine methosulfate sus scrofa 3.0 3.0 1 PMID:2363500 -1.3.8.7 recombinant beta-y16l electron transferring flavoprotein homo sapiens 18.3 18.3 1 PMID:9882619 -1.3.8.7 recombinant electron transferring flavoprotein homo sapiens 14.7 14.7 1 PMID:9882619 -1.3.8.7 tetradecanoyl-coa homo sapiens 6.0 5.335 2 PMID:8823175;PMID:9182995 -1.3.8.7 tetradecanoyl-coa rattus norvegicus 6.0 6.0 1 PMID:3968063 -1.3.8.8 decanoyl-coa homo sapiens 2.25 2.25 1 PMID:8155643 -1.3.8.8 octanoyl-coa homo sapiens 2.25 2.25 1 PMID:8155643 -1.3.8.8 palmitoyl-coa bos taurus 1.67 1.67 1 PMID:1015826 -1.3.8.8 palmitoyl-coa homo sapiens 2.17 2.17 1 PMID:8155643 -1.3.8.8 palmitoyl-coa rattus norvegicus 5.4 2.95 2 PMID:3968064 -1.3.98.1 dihydrooxonate saccharomyces cerevisiae 39.0 39.0 1 PMID:10871048 -1.3.98.1 ferricyanide lactobacillus delbrueckii subsp. bulgaricus 157.0 157.0 1 PMID:5547979 -1.3.98.1 fumarate trypanosoma brucei 8.5 8.5 1 PMID:18312275 -1.3.98.1 l-dihydroorotate plasmodium falciparum 7.8 7.8 1 PMID:15795226 -1.3.98.1 s-dihydroorotate crithidia fasciculata 231.0 117.5 2 PMID:6087880;PMID:6299333 -1.3.98.1 s-dihydroorotate lactobacillus delbrueckii subsp. bulgaricus 2.7 2.7 1 PMID:5547979 -1.3.98.1 s-dihydroorotate saccharomyces cerevisiae 190.0 25.0 3 PMID:10871048 -1.3.98.3 2-deoxy-scyllo-inosamine niallia circulans 0.038 0.038 1 PMID:18001019 -1.3.98.3 coproporphyrinogen iii vibrio vulnificus 900.0 900.0 1 PMID:25626927 -1.3.98.3 s-adenosyl-l-methionine niallia circulans 0.022 0.020999999999999998 2 PMID:18001019;PMID:18672902 -1.3.98.5 h2o2 listeria monocytogenes 0.0065 0.0065 1 PMID:27758026 -1.3.98.5 h2o2 listeria monocytogenes serotype 1/2a 0.0065 0.0065 1 PMID:27758026 -1.3.99.17 quinoline pseudomonas putida 85.4 85.4 4 PMID:12654012;PMID:15296736;PMID:15902470 -1.3.99.33 urocanate shewanella oneidensis 360.0 5.62 3 PMID:23078170;PMID:33649331 -1.3.99.4 11beta,17-dihydroxy-3,20-dioxopregn-4-en-21-yl acetate mycolicibacterium neoaurum 6825.77 6825.77 1 PMID:31289904 -1.3.99.4 11beta,17-dihydroxy-3,20-dioxopregn-4-en-21-yl acetate mycolicibacterium smegmatis 77.2 77.2 1 PMID:28634849 -1.3.99.4 11beta,17-dihydroxy-3,20-dioxopregn-4-en-21-yl acetate rhodococcus erythropolis 20.3 20.3 1 PMID:28634849 -1.3.99.4 11beta,17alpha,21-trihydroxypregn-4-ene-3,20-dione mycolicibacterium neoaurum 2842.34 2842.34 1 PMID:31289904 -1.3.99.4 11beta,17alpha,21-trihydroxypregn-4-ene-3,20-dione mycolicibacterium smegmatis 60.3 60.3 1 PMID:28634849 -1.3.99.4 11beta,17alpha,21-trihydroxypregn-4-ene-3,20-dione rhodococcus erythropolis 50.2 50.2 1 PMID:28634849 -1.3.99.4 16,17alpha-epoxyprogesterone mycolicibacterium neoaurum 13849.8 13849.8 1 PMID:31289904 -1.3.99.4 17-methyl-testosterone pimelobacter simplex 103.1 74.25 2 PMID:32786835 -1.3.99.4 17alpha,21-dihydroxyprogesterone 21-acetate mycolicibacterium neoaurum 8452.5 8452.5 1 PMID:31289904 -1.3.99.4 17alpha,21-dihydroxyprogesterone 21-acetate pimelobacter simplex 126.1 126.1 1 PMID:32786835 -1.3.99.4 17alpha-hydroxypregn-4-ene-3,20-dione mycolicibacterium neoaurum 9929.5 9929.5 1 PMID:31289904 -1.3.99.4 17alpha-hydroxypregn-4-ene-3,20-dione mycolicibacterium smegmatis 110.4 110.4 1 PMID:28634849 -1.3.99.4 17alpha-hydroxypregn-4-ene-3,20-dione rhodococcus erythropolis 21.4 21.4 1 PMID:28634849 -1.3.99.4 17alpha-hydroxyprogesterone pimelobacter simplex 92.8 92.8 1 PMID:32786835 -1.3.99.4 21-acetoxy-pregna-4,9(11),16-triene-3,20-dinone mycolicibacterium smegmatis 13.7 13.7 1 PMID:28634849 -1.3.99.4 21-acetoxy-pregna-4,9(11),16-triene-3,20-dinone rhodococcus erythropolis 26.9 26.9 1 PMID:28634849 -1.3.99.4 21-chloro-17-hydroxy-pregna-4,9(11)-diene-3,20-dione mycolicibacterium smegmatis 63.5 63.5 1 PMID:28634849 -1.3.99.4 21-chloro-17-hydroxy-pregna-4,9(11)-diene-3,20-dione rhodococcus erythropolis 12.8 12.8 1 PMID:28634849 -1.3.99.4 4-androsten-3-one-5-ene-17-carboxylic acid mycolicibacterium smegmatis 94.1 94.1 1 PMID:28634849 -1.3.99.4 4-androsten-3-one-5-ene-17-carboxylic acid rhodococcus erythropolis 40.8 40.8 1 PMID:28634849 -1.3.99.4 4-androstene-3,17-dione mycolicibacterium neoaurum 9625.36 0.096 3 PMID:26886757;PMID:31289904 -1.3.99.4 4-androstene-3,17-dione mycolicibacterium smegmatis 51.5 51.5 1 PMID:28634849 -1.3.99.4 4-androstene-3,17-dione pimelobacter simplex 86.1 82.9 2 PMID:32786835 -1.3.99.4 4-androstene-3,17-dione rhodococcus erythropolis 68.1 57.8 2 PMID:24165124;PMID:28634849 -1.3.99.4 4-androstene-3,17-dione sterolibacterium denitrificans 46.1 46.1 1 PMID:34162386 -1.3.99.4 4-cholesten-3-one pimelobacter simplex 27.8 27.8 1 PMID:32786835 -1.3.99.4 4-cholesten-3-one sterolibacterium denitrificans 5.8 5.8 1 PMID:34162386 -1.3.99.4 9alpha-hydroxy-4-androstene-3,17-dione mycolicibacterium neoaurum 1862.9 1862.9 1 PMID:31289904 -1.3.99.4 9alpha-hydroxy-4-androstene-3,17-dione mycolicibacterium smegmatis 58.7 58.7 1 PMID:28634849 -1.3.99.4 9alpha-hydroxy-4-androstene-3,17-dione rhodococcus erythropolis 21.4 21.4 1 PMID:28634849 -1.3.99.4 androst-4,9(11)-diene-3,17-dione mycolicibacterium smegmatis 10.2 10.2 1 PMID:28634849 -1.3.99.4 androst-4,9(11)-diene-3,17-dione rhodococcus erythropolis 22.3 22.3 1 PMID:28634849 -1.3.99.4 androsta-4,9(11)-diene-3,17-dione mycolicibacterium neoaurum 6475.3 6475.3 1 PMID:31289904 -1.3.99.4 canrenone mycolicibacterium neoaurum 2774.12 2774.12 1 PMID:31289904 -1.3.99.4 canrenone pimelobacter simplex 95.8 95.8 1 PMID:32786835 -1.3.99.4 cortexolone mycolicibacterium smegmatis 94.2 94.2 1 PMID:28634849 -1.3.99.4 cortexolone rhodococcus erythropolis 20.6 20.6 1 PMID:28634849 -1.3.99.4 cortisone mycolicibacterium smegmatis 52.2 52.2 1 PMID:28634849 -1.3.99.4 cortisone rhodococcus erythropolis 24.6 24.6 1 PMID:28634849 -1.3.99.4 cortisone acetate pimelobacter simplex 67.4 67.4 1 PMID:32786835 -1.3.99.4 pregna-4,9(11),16-triene-3,20-dione mycolicibacterium smegmatis 14.4 14.4 1 PMID:28634849 -1.3.99.4 progesterone mycolicibacterium smegmatis 127.8 127.8 1 PMID:28634849 -1.3.99.4 progesterone pimelobacter simplex 57.7 36.7 2 PMID:32786835 -1.3.99.4 progesterone rhodococcus erythropolis 25.4 25.4 1 PMID:28634849 -1.3.99.4 testosterone mycolicibacterium smegmatis 77.5 77.5 1 PMID:28634849 -1.3.99.4 testosterone pimelobacter simplex 59.2 41.95 2 PMID:32786835 -1.3.99.4 testosterone rhodococcus erythropolis 25.8 25.8 1 PMID:28634849 -1.3.99.5 (5alpha)-androst-1-en-3,17-dione rhodococcus jostii 2.4 2.4 1 PMID:22833669 -1.4.1.1 2-oxobutyrate archaeoglobus fulgidus 143.0 143.0 1 PMID:15516582 -1.4.1.1 l-2-aminobutyrate archaeoglobus fulgidus 9.6 9.6 1 PMID:15516582 -1.4.1.1 l-ala archaeoglobus fulgidus 6.1 6.1 1 PMID:15516582 -1.4.1.1 l-ala mycobacterium tuberculosis 126.0 126.0 1 PMID:18304579 -1.4.1.1 l-ala shewanella sp. 228.0 75.0 5 PMID:12664266 -1.4.1.1 l-alanine alkalihalophilus pseudofirmus 10.0 10.0 1 PMID:29310857 -1.4.1.1 l-alanine amycolatopsis sulphurea 13.24 13.24 1 PMID:33818657 -1.4.1.1 l-alanine mycobacterium tuberculosis 7.5 7.5 1 PMID:25538307 -1.4.1.1 l-serine mycobacterium tuberculosis 0.24 0.24 1 PMID:25538307 -1.4.1.1 nad+ alkalihalophilus pseudofirmus 6.0 6.0 1 PMID:29310857 -1.4.1.1 nad+ archaeoglobus fulgidus 6.1 6.1 1 PMID:15516582 -1.4.1.1 nad+ phormidium lapideum 95.5 95.5 1 * -1.4.1.1 nad+ shewanella sp. 211.0 95.5 8 PMID:12664266 -1.4.1.1 nadh archaeoglobus fulgidus 118.0 118.0 1 PMID:15516582 -1.4.1.1 nadh bacillus subtilis 13.96 13.96 1 PMID:26202482 -1.4.1.1 nadh shewanella sp. 2871.0 2209.0 3 PMID:12664266 -1.4.1.1 nadp+ shewanella sp. 1.6 1.6 1 * -1.4.1.1 nadph bacillus subtilis 11.1 11.1 1 PMID:26202482 -1.4.1.1 nh4+ archaeoglobus fulgidus 118.0 118.0 1 PMID:15516582 -1.4.1.1 nh4+ shewanella sp. 2472.0 1755.0 3 PMID:12664266 -1.4.1.1 oxaloacetate archaeoglobus fulgidus 113.0 113.0 1 PMID:15516582 -1.4.1.1 pyruvate archaeoglobus fulgidus 118.0 118.0 1 PMID:15516582 -1.4.1.1 pyruvate mycobacterium tuberculosis 694.0 694.0 1 PMID:18304579 -1.4.1.1 pyruvate shewanella sp. 2562.0 1963.0 3 PMID:12664266 -1.4.1.12 (2r,4s)-2,4-diaminopentanoate fervidobacterium nodosum 65.0 65.0 1 PMID:24326351 -1.4.1.12 (2r,5s)-2,5-diaminohexanoate fervidobacterium nodosum 0.0006 0.0006 1 PMID:24326351 -1.4.1.12 nad+ acetoanaerobium sticklandii 34.0 34.0 1 PMID:19251850 -1.4.1.12 nad+ fervidobacterium nodosum 65.0 65.0 1 PMID:24326351 -1.4.1.12 nadp+ acetoanaerobium sticklandii 5.0 5.0 1 PMID:19251850 -1.4.1.12 nadp+ fervidobacterium nodosum 57.0 57.0 1 PMID:24326351 -1.4.1.13 ferricyanide azospirillum brasilense 41.9 40.7 2 PMID:8665916 -1.4.1.13 iodonitrotetrazolium azospirillum brasilense 32.0 26.0 2 PMID:8665916 -1.4.1.13 menadione azospirillum brasilense 25.3 25.3 1 PMID:8665916 -1.4.1.13 nadph azospirillum brasilense 30.8 24.55 2 PMID:8665916 -1.4.1.13 nadph pyrococcus horikoshii 26.8 11.36 4 PMID:20630732 -1.4.1.14 3-acetylpyridine adenine dinucleotide lupinus angustifolius 51.0 34.5 2 PMID:7238515 -1.4.1.14 l-glutamine lupinus angustifolius 70.0 70.0 1 PMID:21790 -1.4.1.14 l-glutamine oryza sativa 32.0 32.0 1 PMID:16668794 -1.4.1.14 nadh lupinus angustifolius 70.0 70.0 1 PMID:7238515 -1.4.1.16 2-oxovalerate corynebacterium glutamicum 0.93 0.93 1 PMID:29421037 -1.4.1.16 3-methyl-2-oxobutanoate corynebacterium glutamicum 0.27 0.27 1 PMID:29421037 -1.4.1.16 4-methyl-2-oxopentanoate corynebacterium glutamicum 0.12 0.12 1 PMID:29421037 -1.4.1.16 l-delta1-tetrahydrodipicolinate acetivibrio thermocellus 278.2 278.2 1 PMID:30787467 -1.4.1.16 l-delta1-tetrahydrodipicolinate bacteroides fragilis 4.9 4.9 1 PMID:30787467 -1.4.1.16 l-delta1-tetrahydrodipicolinate corynebacterium glutamicum 41.9 41.9 1 PMID:30787467 -1.4.1.16 l-delta1-tetrahydrodipicolinate lysinibacillus sphaericus 64.7 64.7 1 PMID:30787467 -1.4.1.16 l-delta1-tetrahydrodipicolinate symbiobacterium thermophilum 52.8 52.8 1 PMID:30787467 -1.4.1.16 l-delta1-tetrahydrodipicolinate ureibacillus thermosphaericus 50.6 50.6 1 PMID:30787467 -1.4.1.16 meso-2,6-diaminoheptanedioate acetivibrio thermocellus 344.3 344.3 1 PMID:30787467 -1.4.1.16 meso-2,6-diaminoheptanedioate bacteroides fragilis 7.7 7.7 1 PMID:30787467 -1.4.1.16 meso-2,6-diaminoheptanedioate corynebacterium glutamicum 115.4 83.69500000000001 2 PMID:29421037;PMID:30787467 -1.4.1.16 meso-2,6-diaminoheptanedioate lysinibacillus sphaericus 154.2 154.2 1 PMID:30787467 -1.4.1.16 meso-2,6-diaminoheptanedioate numidum massiliense 638.0 638.0 1 PMID:32485072 -1.4.1.16 meso-2,6-diaminoheptanedioate symbiobacterium thermophilum 127000.0 40.47 5 PMID:23023754;PMID:28341677;PMID:29421037;PMID:30787467;PMID:30807172 -1.4.1.16 meso-2,6-diaminoheptanedioate thermosyntropha lipolytica 737.0 737.0 1 PMID:32599299 -1.4.1.16 meso-2,6-diaminoheptanedioate ureibacillus thermosphaericus 123.3 123.3 1 PMID:30787467 -1.4.1.16 nad+ numidum massiliense 8933.0 8933.0 1 PMID:32485072 -1.4.1.16 nad+ thermosyntropha lipolytica 775.0 775.0 1 PMID:32599299 -1.4.1.16 nadh pseudothermotoga thermarum 5.97 5.97 1 PMID:30458240 -1.4.1.16 nadp+ numidum massiliense 792.0 792.0 1 PMID:32485072 -1.4.1.16 nadp+ symbiobacterium thermophilum 25.47 25.47 1 PMID:28341677 -1.4.1.16 nadp+ thermosyntropha lipolytica 830.0 830.0 1 PMID:32599299 -1.4.1.16 nadph pseudothermotoga thermarum 0.73 0.73 1 PMID:30458240 -1.4.1.16 nadph symbiobacterium thermophilum 6.97 6.97 1 PMID:28341677 -1.4.1.16 nh4+ acetivibrio thermocellus 1815.6 1815.6 1 PMID:30787467 -1.4.1.16 nh4+ bacteroides fragilis 160.8 160.8 1 PMID:30787467 -1.4.1.16 nh4+ corynebacterium glutamicum 768.3 768.3 1 PMID:30787467 -1.4.1.16 nh4+ lysinibacillus sphaericus 511.9 511.9 1 PMID:30787467 -1.4.1.16 nh4+ symbiobacterium thermophilum 387.4 387.4 1 PMID:30787467 -1.4.1.16 nh4+ ureibacillus thermosphaericus 347.7 347.7 1 PMID:30787467 -1.4.1.16 oxaloacetate corynebacterium glutamicum 0.087 0.087 1 PMID:29421037 -1.4.1.16 phenylpyruvate symbiobacterium thermophilum 0.11 0.11 1 PMID:23728814 -1.4.1.16 pyruvate corynebacterium glutamicum 1.35 1.35 1 PMID:29421037 -1.4.1.16 pyruvate symbiobacterium thermophilum 7850.0 7.305 4 PMID:23023754;PMID:28341677;PMID:29421037;PMID:30807172 -1.4.1.19 (indol-3-yl)pyruvate nostoc punctiforme 16.0 16.0 1 PMID:24835098 -1.4.1.19 l-tryptophan nostoc punctiforme 20.0 12.1 2 PMID:24835098;PMID:27815281 -1.4.1.19 nad+ nostoc punctiforme 4.3 4.3 1 PMID:24835098 -1.4.1.19 nadh nostoc punctiforme 21.0 21.0 1 PMID:24835098 -1.4.1.19 nh3 nostoc punctiforme 17.0 17.0 1 PMID:24835098 -1.4.1.2 2-oxoglutarate bacillus subtilis 344.0 343.0 2 PMID:16195607;PMID:16244435 -1.4.1.2 2-oxoglutarate halobacterium salinarum 56.0 51.0 2 PMID:22527040 -1.4.1.2 2-oxoglutarate peptoniphilus asaccharolyticus 20.3 20.3 1 PMID:15727821 -1.4.1.2 2-oxoglutarate pyrobaculum calidifontis 65.0 65.0 1 PMID:23508687 -1.4.1.2 glutamate peptoniphilus asaccharolyticus 6.7 6.7 1 PMID:15727821 -1.4.1.2 l-glutamate arabidopsis thaliana 13.3 13.3 2 PMID:32655590 -1.4.1.2 l-glutamate bacillus subtilis 18.1 18.1 1 PMID:16244435 -1.4.1.2 l-glutamate halobacterium salinarum 24.0 20.5 2 PMID:22527040 -1.4.1.2 l-glutamate pyrobaculum calidifontis 17.0 17.0 1 PMID:23508687 -1.4.1.2 nad+ halobacterium salinarum 16.0 15.5 2 PMID:22527040 -1.4.1.2 nad+ peptoniphilus asaccharolyticus 6.0 6.0 1 PMID:15727821 -1.4.1.2 nad+ pyrobaculum calidifontis 14.0 14.0 1 PMID:23508687 -1.4.1.2 nadh [clostridium] symbiosum 232.0 130.2 3 PMID:21876794 -1.4.1.2 nadh halobacterium salinarum 47.0 43.0 2 PMID:22527040 -1.4.1.2 nadh peptoniphilus asaccharolyticus 31.4 31.35 2 PMID:15727821;PMID:17850332 -1.4.1.2 nadh pyrobaculum calidifontis 58.0 58.0 1 PMID:23508687 -1.4.1.2 nadp+ peptoniphilus asaccharolyticus 0.16 0.16 1 PMID:15727821 -1.4.1.2 nadph peptoniphilus asaccharolyticus 12.0 11.0 2 PMID:15727821;PMID:17850332 -1.4.1.2 nh3 halobacterium salinarum 85.0 84.5 2 PMID:22527040 -1.4.1.2 nh3 pyrobaculum calidifontis 58.0 58.0 1 PMID:23508687 -1.4.1.2 nh4+ peptoniphilus asaccharolyticus 20.4 20.4 1 PMID:15727821 -1.4.1.20 2-oxo-4-methylpentanoate thermoactinomyces intermedius 26.0 26.0 1 PMID:8407879 -1.4.1.20 2-oxo-4-methylthiobutanoate thermoactinomyces intermedius 37.0 37.0 1 PMID:8407879 -1.4.1.20 2-oxohexanoate thermoactinomyces intermedius 79.0 79.0 1 PMID:8407879 -1.4.1.20 2-oxoisohexanoate thermoactinomyces intermedius 57.0 57.0 1 PMID:8407879 -1.4.1.20 2-oxopentanoate thermoactinomyces intermedius 82.0 82.0 1 PMID:8407879 -1.4.1.20 4-methyl-2-oxopentanoate lysinibacillus sphaericus 27.0 27.0 1 PMID:12234181 -1.4.1.20 alpha-keto-gamma-methiobutyrate lysinibacillus sphaericus 27.0 27.0 1 PMID:12234181 -1.4.1.20 alpha-ketocaproate lysinibacillus sphaericus 51.0 51.0 1 PMID:12234181 -1.4.1.20 alpha-ketovalerate lysinibacillus sphaericus 33.0 33.0 1 PMID:12234181 -1.4.1.20 dl-alpha-keto-beta-methyl-n-valerate lysinibacillus sphaericus 7.2 7.2 1 PMID:12234181 -1.4.1.20 dl-propargylglycine lysinibacillus sphaericus 1.82 0.97 14 PMID:19501264 -1.4.1.20 l-ethionine thermoactinomyces intermedius 1.1 1.1 1 PMID:8407879 -1.4.1.20 l-ile thermoactinomyces intermedius 0.24 0.24 1 PMID:8407879 -1.4.1.20 l-isoleucine lysinibacillus sphaericus 0.14 0.14 1 PMID:12234181 -1.4.1.20 l-leu thermoactinomyces intermedius 3.6 3.6 1 PMID:8407879 -1.4.1.20 l-leucine lysinibacillus sphaericus 0.7 0.7 1 PMID:12234181 -1.4.1.20 l-met thermoactinomyces intermedius 0.84 0.84 1 PMID:8407879 -1.4.1.20 l-methionine lysinibacillus sphaericus 1.2 1.2 1 PMID:12234181 -1.4.1.20 l-norleucine lysinibacillus sphaericus 3.2 3.2 1 PMID:12234181 -1.4.1.20 l-norleucine thermoactinomyces intermedius 1.9 1.9 1 PMID:8407879 -1.4.1.20 l-norvaline lysinibacillus sphaericus 1.4 1.4 1 PMID:12234181 -1.4.1.20 l-norvaline thermoactinomyces intermedius 0.59 0.59 1 PMID:8407879 -1.4.1.20 l-phe pseudobacillus badius 816.0 765.0 2 PMID:16215831 -1.4.1.20 l-phe thermoactinomyces intermedius 45.0 45.0 1 PMID:8407879 -1.4.1.20 l-phenylalanine lysinibacillus sphaericus 68.01 4.08 15 PMID:12234181;PMID:19501264 -1.4.1.20 l-phenylalanine pseudobacillus badius 50.0 44.5 2 PMID:12234181;PMID:29051071 -1.4.1.20 l-phenylalanine sporosarcina ureae 49.56 18.630000000000003 4 PMID:20658209 -1.4.1.20 l-tyrosine lysinibacillus sphaericus 68.0 68.0 1 PMID:12234181 -1.4.1.20 l-tyrosine pseudobacillus badius 58.0 46.0 2 PMID:12234181;PMID:29051071 -1.4.1.20 l-valine lysinibacillus sphaericus 0.91 0.91 1 PMID:12234181 -1.4.1.20 p-hydroxy-phenylpyruvate lysinibacillus sphaericus 90.0 90.0 1 PMID:12234181 -1.4.1.20 phenylpyruvate lysinibacillus sphaericus 113.0 113.0 1 PMID:12234181 -1.4.1.20 phenylpyruvate thermoactinomyces intermedius 91.0 91.0 1 PMID:8407879 -1.4.1.21 l-asp thermotoga maritima 4.9 2.8400000000000003 2 PMID:12496312 -1.4.1.21 l-aspartate bradyrhizobium japonicum 7.3 7.3 1 * -1.4.1.21 l-aspartate pseudomonas aeruginosa 59.7 51.2 2 PMID:21468714 -1.4.1.21 l-aspartate rhodopseudomonas palustris 2.86 2.86 1 * -1.4.1.21 l-aspartate thermotoga maritima 4.9 2.8400000000000003 2 PMID:12496312 -1.4.1.21 nad+ bradyrhizobium japonicum 3.3 3.3 1 * -1.4.1.21 nad+ pseudomonas aeruginosa 62.9 62.9 1 PMID:21468714 -1.4.1.21 nad+ rhodopseudomonas palustris 1.59 1.59 1 * -1.4.1.21 nad+ thermotoga maritima 1.2 1.2 1 PMID:12496312 -1.4.1.21 nadh bradyrhizobium japonicum 26.2 26.2 1 * -1.4.1.21 nadh pseudomonas aeruginosa 70.5 69.45 2 PMID:21468714;PMID:30458240 -1.4.1.21 nadh rhodopseudomonas palustris 5.2 5.2 1 * -1.4.1.21 nadp+ bradyrhizobium japonicum 6.2 6.2 1 * -1.4.1.21 nadp+ pseudomonas aeruginosa 46.1 46.1 1 PMID:21468714 -1.4.1.21 nadp+ rhodopseudomonas palustris 2.33 2.33 1 * -1.4.1.21 nadp+ thermotoga maritima 7.2 7.2 1 PMID:12496312 -1.4.1.21 nadph bradyrhizobium japonicum 41.0 41.0 1 * -1.4.1.21 nadph pseudomonas aeruginosa 80.2 80.2 1 PMID:21468714;PMID:30458240 -1.4.1.21 nadph rhodopseudomonas palustris 19.0 19.0 1 * -1.4.1.21 nh3 bradyrhizobium japonicum 24.7 24.7 1 * -1.4.1.21 nh3 pseudomonas aeruginosa 77.6 69.8 2 PMID:21468714 -1.4.1.21 nh3 rhodopseudomonas palustris 10.3 10.3 1 * -1.4.1.21 oxaloacetate bradyrhizobium japonicum 48.0 48.0 1 * -1.4.1.21 oxaloacetate pseudomonas aeruginosa 71.6 70.0 2 PMID:21468714 -1.4.1.21 oxaloacetate rhodopseudomonas palustris 14.2 14.2 1 * -1.4.1.23 2-oxobutanoate streptomyces virginiae 99.0 99.0 1 PMID:2803248 -1.4.1.23 2-oxohexanoate streptomyces virginiae 107.0 107.0 1 PMID:2803248 -1.4.1.23 2-oxoisohexanoate streptomyces virginiae 71.9 71.9 1 PMID:2803248 -1.4.1.23 2-oxoisovalerate streptomyces virginiae 226.0 226.0 1 PMID:2803248 -1.4.1.23 2-oxovalerate streptomyces virginiae 164.0 164.0 1 PMID:2803248 -1.4.1.23 l-2-aminobutanoate streptomyces virginiae 104.0 104.0 1 PMID:2803248 -1.4.1.23 l-isoleucine streptomyces virginiae 5.8 5.8 1 PMID:2803248 -1.4.1.23 l-leucine streptomyces virginiae 11.9 11.9 1 PMID:2803248 -1.4.1.23 l-norleucine streptomyces virginiae 17.9 17.9 1 PMID:2803248 -1.4.1.23 l-norvaline streptomyces virginiae 18.0 18.0 1 PMID:2803248 -1.4.1.23 l-valine streptomyces virginiae 28.3 28.3 1 PMID:2803248 -1.4.1.23 pyruvate streptomyces virginiae 114.0 114.0 1 PMID:2803248 -1.4.1.26 (2r,4s)-2,4-diaminopentanoate fervidobacterium nodosum 65.0 65.0 1 PMID:24326351 -1.4.1.26 2,5-diaminohexanoate fervidobacterium nodosum 0.0006 0.0006 1 PMID:24326351 -1.4.1.26 nad+ fervidobacterium nodosum 65.0 65.0 1 PMID:24326351 -1.4.1.26 nadp+ fervidobacterium nodosum 57.0 57.0 1 PMID:24326351 -1.4.1.28 1-hydroxybutan-2-one geobacillus stearothermophilus 1.79 1.28 2 * -1.4.1.28 1-hydroxybutan-2-one lysinibacillus sphaericus 1.52 1.52 1 * -1.4.1.28 1-hydroxybutan-2-one sporosarcina psychrophila 0.74 0.74 1 * -1.4.1.28 1-hydroxybutan-2-one thermoactinomyces intermedius 0.32 0.32 1 * -1.4.1.28 2-methylcyclohexanone mycolicibacterium smegmatis 0.61 0.61 1 * -1.4.1.28 cyclohexanone cystobacter fuscus 13.0 6.565 2 * -1.4.1.28 cyclohexanone mycolicibacterium smegmatis 0.94 0.94 1 * -1.4.1.28 isobutanal cystobacter fuscus 0.11 0.11 1 * -1.4.1.28 isobutanal mycolicibacterium smegmatis 0.54 0.54 1 * -1.4.1.28 nadh cystobacter fuscus 0.1 0.1 1 * -1.4.1.28 nadh mycolicibacterium smegmatis 0.58 0.58 1 * -1.4.1.28 nadph cystobacter fuscus 0.05 0.05 1 * -1.4.1.28 nadph mycolicibacterium smegmatis 0.28 0.28 1 * -1.4.1.28 nh3 cystobacter fuscus 0.04 0.04 1 * -1.4.1.28 nh3 mycolicibacterium smegmatis 0.3 0.3 1 * -1.4.1.28 nh3 petrotoga mobilis 37.8 37.8 1 * -1.4.1.3 2-oxoglutarate azospirillum brasilense 183.0 183.0 1 PMID:3956501 -1.4.1.3 2-oxoglutarate bos taurus 50.0 50.0 1 PMID:12981035 -1.4.1.3 2-oxoglutarate homo sapiens 130.0 117.0 4 PMID:15044002;PMID:15750346 -1.4.1.3 2-oxoglutarate pyrococcus 195.0 195.0 1 PMID:9520268 -1.4.1.3 2-oxoglutarate pyrococcus horikoshii 165.3 165.3 1 PMID:12590923 -1.4.1.3 2-oxoglutarate thermus thermophilus 37.0 7.83 4 PMID:31036724 -1.4.1.3 2-oxoglutarate thunnus thynnus 510.0 510.0 1 PMID:182270 -1.4.1.3 glutamate azospirillum brasilense 61.0 61.0 1 PMID:3956501 -1.4.1.3 glutamate pyrococcus 162.0 101.0 2 PMID:9520268 -1.4.1.3 glutamate tenebrio molitor 714.0 714.0 1 * -1.4.1.3 glutamate thunnus thynnus 25.0 25.0 1 PMID:182270 -1.4.1.3 l-glutamate azospirillum brasilense 3.33 3.33 1 PMID:3956501 -1.4.1.3 l-glutamate bos taurus 4.83 4.83 1 PMID:12981035 -1.4.1.3 l-glutamate homo sapiens 83.0 74.0 2 PMID:15194228 -1.4.1.3 l-glutamate pyrococcus horikoshii 121.2 121.2 1 PMID:12590923 -1.4.1.3 l-glutamate thermus thermophilus 13.0 2.95 6 PMID:31036724 -1.4.1.3 nad+ homo sapiens 83.0 65.0 3 PMID:12193607;PMID:15194228 -1.4.1.3 nad+ thermus thermophilus 12.0 6.4 4 PMID:31036724 -1.4.1.3 nadh homo sapiens 130.0 104.0 9 PMID:12681501;PMID:15044002;PMID:16023112;PMID:17507377;PMID:18261983 -1.4.1.3 nadh pyrococcus 90.0 90.0 1 PMID:9520268 -1.4.1.3 nadh pyrococcus horikoshii 374.5 374.5 1 PMID:12590923 -1.4.1.3 nadh thermus thermophilus 29.0 4.91 4 PMID:31036724 -1.4.1.3 nadp+ pyrococcus 102.0 102.0 1 PMID:9520268 -1.4.1.3 nadp+ pyrococcus horikoshii 399.6 399.6 1 PMID:12590923 -1.4.1.3 nadph azospirillum brasilense 200.0 200.0 1 PMID:3956501 -1.4.1.3 nadph pyrococcus 112.0 112.0 1 PMID:9520268 -1.4.1.3 nadph pyrococcus horikoshii 387.5 387.5 1 PMID:12590923 -1.4.1.3 nh3 thermus thermophilus 44.0 8.55 4 PMID:31036724 -1.4.1.3 nh4+ pyrococcus 168.0 115.65 2 PMID:9520268 -1.4.1.3 nh4+ pyrococcus horikoshii 43.8 43.8 1 PMID:12590923 -1.4.1.4 2-oxoglutarate bacillus licheniformis 0.15 0.15 1 PMID:28193334 -1.4.1.4 2-oxoglutarate corynebacterium glutamicum 2500.0 2500.0 1 PMID:28486765 -1.4.1.4 2-oxoglutarate kluyveromyces lactis 21.0 13.5 2 PMID:27864882 -1.4.1.4 2-oxoglutarate lachancea kluyveri 20.0 15.0 2 PMID:27864882 -1.4.1.4 2-oxoglutarate plasmodium falciparum 53.33 39.165 2 PMID:22342964 -1.4.1.4 2-oxoglutarate pyrobaculum calidifontis 95.0 95.0 1 PMID:23508687 -1.4.1.4 2-oxoglutarate saccharomyces cerevisiae 14.0 13.0 4 PMID:27864882 -1.4.1.4 2-oxoglutarate thermococcus waiotapuensis 2530.0 2530.0 1 PMID:12013436 -1.4.1.4 l-glutamate bacillus licheniformis 0.06 0.06 1 PMID:28193334 -1.4.1.4 l-glutamate corynebacterium glutamicum 9.3 9.3 1 PMID:28486765 -1.4.1.4 l-glutamate escherichia coli 17.1 17.1 1 PMID:30583861 -1.4.1.4 l-glutamate plasmodium falciparum 78.33 39.3485 2 PMID:22342964 -1.4.1.4 l-glutamate pyrobaculum calidifontis 13.0 13.0 1 PMID:23508687 -1.4.1.4 l-glutamate thermococcus waiotapuensis 141.0 141.0 1 PMID:12013436 -1.4.1.4 nad+ symbiobacterium toebii 1.5 1.5 1 * -1.4.1.4 nadh corynebacterium glutamicum 1.4 1.4 1 PMID:28486765 -1.4.1.4 nadh symbiobacterium toebii 6144.0 6144.0 1 * -1.4.1.4 nadp+ corynebacterium glutamicum 8.1 8.1 1 PMID:28486765 -1.4.1.4 nadp+ escherichia coli 37.3 27.0 2 PMID:23879525;PMID:30583861 -1.4.1.4 nadp+ pyrobaculum calidifontis 9.9 9.9 1 PMID:23508687 -1.4.1.4 nadp+ symbiobacterium toebii 2136.0 2136.0 1 * -1.4.1.4 nadp+ thermococcus waiotapuensis 1209.0 1209.0 1 PMID:12013436 -1.4.1.4 nadph bacillus licheniformis 0.18 0.18 1 PMID:28193334 -1.4.1.4 nadph corallomycetella repens 1100.0 1100.0 1 * -1.4.1.4 nadph corynebacterium glutamicum 2200.0 2200.0 1 PMID:28486765 -1.4.1.4 nadph pyrobaculum calidifontis 92.0 92.0 1 PMID:23508687 -1.4.1.4 nadph symbiobacterium toebii 28650.0 28650.0 1 * -1.4.1.4 nadph thermococcus waiotapuensis 14710.0 14710.0 1 PMID:12013436 -1.4.1.4 nh3 corynebacterium glutamicum 3400.0 3400.0 1 PMID:28486765 -1.4.1.4 nh3 pyrobaculum calidifontis 100.0 100.0 1 PMID:23508687 -1.4.1.4 nh3 thermococcus waiotapuensis 163.0 163.0 1 PMID:12013436 -1.4.1.5 l-glutamine proteus sp. (in: enterobacteria) 1.15 1.15 1 PMID:18051956 -1.4.1.5 l-isoleucine citrobacter sp. 2.84 2.84 1 PMID:18051956 -1.4.1.5 l-methionine proteus sp. (in: enterobacteria) 2.11 2.11 1 PMID:18051956 -1.4.1.5 l-valine pseudomonas sp. 4.95 4.95 1 PMID:18051956 -1.4.1.7 3-methyl-dl-serine pseudomonas aeruginosa 9.6 9.6 1 PMID:22128181 -1.4.1.7 dl-glycerate pseudomonas aeruginosa 5.8 5.8 1 PMID:22128181 -1.4.1.7 l-serine pseudomonas aeruginosa 10.4 10.4 1 PMID:22128181 -1.4.1.7 methyl 2,2-dimethyl-3-hydroxypropionic acid pseudomonas aeruginosa 11.6 11.6 1 PMID:22128181 -1.4.1.7 nad+ pseudomonas aeruginosa 1.6 1.6 1 PMID:22128181 -1.4.1.8 2-oxobutyrate streptomyces virginiae 99.0 99.0 1 PMID:2803248 -1.4.1.8 2-oxocaproate streptomyces virginiae 107.0 107.0 1 PMID:2803248 -1.4.1.8 2-oxoisocaproate streptomyces virginiae 71.9 71.9 1 PMID:2803248 -1.4.1.8 2-oxoisovalerate streptomyces albus 315.0 315.0 1 PMID:10612726 -1.4.1.8 2-oxoisovalerate streptomyces virginiae 226.0 226.0 1 PMID:2803248 -1.4.1.8 2-oxovalerate streptomyces virginiae 164.0 164.0 1 PMID:2803248 -1.4.1.8 l-2-aminobutyrate streptomyces virginiae 104.0 104.0 1 PMID:2803248 -1.4.1.8 l-isoleucine streptomyces virginiae 5.75 5.75 1 PMID:2803248 -1.4.1.8 l-leucine streptomyces virginiae 11.9 11.9 1 PMID:2803248 -1.4.1.8 l-norleucine streptomyces virginiae 17.9 17.9 1 PMID:2803248 -1.4.1.8 l-norvaline streptomyces virginiae 18.0 18.0 1 PMID:2803248 -1.4.1.8 l-valine streptomyces albus 47.5 47.5 1 PMID:10612726;PMID:11386345 -1.4.1.8 l-valine streptomyces virginiae 28.3 28.3 1 PMID:2803248 -1.4.1.8 pyruvate streptomyces virginiae 114.0 114.0 1 PMID:2803248 -1.4.1.9 2-oxo-3-methylbutanoate bacillus cereus 0.478 0.478 1 PMID:30052323 -1.4.1.9 2-oxobutanoate bacillus cereus 0.149 0.056 3 PMID:28000046;PMID:30052323 -1.4.1.9 2-oxohexanoate geobacillus stearothermophilus 110.0 110.0 1 * -1.4.1.9 2-oxopentanoate bacillus cereus 0.332 0.332 1 PMID:30052323 -1.4.1.9 2-oxopentanoate heyndrickxia coagulans 0.125 0.125 1 * -1.4.1.9 2-oxopentanoate lysinibacillus sphaericus 47.69 47.69 1 PMID:18626578 -1.4.1.9 3,3-dimethyl-2-oxobutanoate alloalcanivorax dieselolei 10.4 10.4 1 * -1.4.1.9 3,3-dimethyl-2-oxobutanoate bacillus cereus 40.4 29.9 2 PMID:27387958 -1.4.1.9 3,3-dimethyl-2-oxobutanoate lysinibacillus sphaericus 31.0 31.0 1 PMID:26898942 -1.4.1.9 3-methyl-2-oxopentanoate lysinibacillus sphaericus 27.63 27.63 1 PMID:18626578 -1.4.1.9 4-methyl-2-oxopentanoate bacillus cereus 0.467 0.467 1 PMID:30052323 -1.4.1.9 4-methyl-2-oxopentanoate lysinibacillus sphaericus 99.38 99.38 1 PMID:18626578 -1.4.1.9 alpha-keto-beta-methylvalerate geobacillus stearothermophilus 280.0 280.0 1 * -1.4.1.9 alpha-keto-isocaproate geobacillus stearothermophilus 280.0 280.0 1 * -1.4.1.9 dl-methionine pseudoalteromonas sp. ant 178 16.6 16.6 1 PMID:30275355 -1.4.1.9 l-arginine pseudoalteromonas sp. ant 178 14.1 14.1 1 PMID:30275355 -1.4.1.9 l-ile geobacillus stearothermophilus 8.0 8.0 1 * -1.4.1.9 l-ile lysinibacillus sphaericus 3.31 3.31 1 PMID:18626578 -1.4.1.9 l-leu geobacillus stearothermophilus 50.0 50.0 1 * -1.4.1.9 l-leu lysinibacillus sphaericus 10.83 10.83 1 PMID:18626578 -1.4.1.9 l-leucine exiguobacterium artemiae 4.3 4.3 1 PMID:32296684 -1.4.1.9 l-leucine planifilum fimeticola 2.3 2.3 1 PMID:33859982 -1.4.1.9 l-leucine pseudoalteromonas sp. ant 178 30.13 30.13 1 PMID:30275355 -1.4.1.9 l-leucine sporosarcina psychrophila 10.0 10.0 1 * -1.4.1.9 l-norleucine geobacillus stearothermophilus 1.3 1.3 1 * -1.4.1.9 l-norleucine lysinibacillus sphaericus 0.18 0.18 1 PMID:18626578 -1.4.1.9 l-norvaline geobacillus stearothermophilus 13.0 13.0 1 * -1.4.1.9 l-norvaline lysinibacillus sphaericus 1.53 1.53 1 PMID:18626578 -1.4.1.9 l-proline pseudoalteromonas sp. ant 178 20.8 20.8 1 PMID:30275355 -1.4.1.9 l-tert-leucine roseibium aggregatum 33.9 33.9 1 * -1.4.1.9 l-tyrosine pseudoalteromonas sp. ant 178 26.4 26.4 1 PMID:30275355 -1.4.1.9 nad+ exiguobacterium artemiae 8.4 8.4 1 PMID:32296684 -1.4.1.9 nad+ planifilum fimeticola 1.8 1.8 1 PMID:33859982 -1.4.1.9 nad+ thermoactinomyces intermedius 90.0 90.0 1 PMID:9278282 -1.4.1.9 nadh alloalcanivorax dieselolei 1.1 1.1 1 * -1.4.1.9 nadh bacillus cereus 33.7 4.25 4 PMID:27387958;PMID:30052323;PMID:33929595 -1.4.1.9 nadh exiguobacterium artemiae 76.9 76.9 1 PMID:32296684 -1.4.1.9 nadh lysinibacillus sphaericus 96.0 96.0 1 PMID:26898942 -1.4.1.9 nadh planifilum fimeticola 6.1 6.1 1 PMID:33859982 -1.4.1.9 nadh roseibium aggregatum 347.0 347.0 1 * -1.4.1.9 oxo(phenyl)acetate bacillus cereus 0.182 0.182 1 PMID:30052323 -1.4.1.9 trimethylpyruvate bacillus cereus 94.1 47.058 2 PMID:30052323;PMID:33929595 -1.4.1.9 trimethylpyruvate exiguobacterium artemiae 45.4 45.4 1 PMID:32296684 -1.4.1.9 trimethylpyruvate planifilum fimeticola 39.1 39.1 1 PMID:33859982 -1.4.1.9 trimethylpyruvate roseibium aggregatum 347.0 347.0 1 * -1.4.2.3 4-(methylamino)-1-(pyridin-3-yl)butan-1-one pseudomonas sp. 151.0 151.0 1 PMID:22267672 -1.4.2.3 ferricytochrome c protein cycn pseudomonas putida 4.4 4.4 1 PMID:35835223 -1.4.2.3 pseudooxynicotine pseudomonas putida 0.79 0.79 1 PMID:26634650 -1.4.3.1 d-alanine vanrija humicola 1.62 1.62 1 PMID:23132574 -1.4.3.1 d-asp caenorhabditis elegans 26.1 9.49 3 PMID:20564561 -1.4.3.1 d-asp homo sapiens 68.4 68.4 1 PMID:25747990 -1.4.3.1 d-asp mus musculus 9.83 9.83 1 PMID:25747990 -1.4.3.1 d-asp rattus norvegicus 31.1 31.1 1 PMID:25747990 -1.4.3.1 d-asp vanrija humicola 74.5 74.5 2 PMID:26519738 -1.4.3.1 d-asparagine caenorhabditis elegans 4.29 3.6799999999999997 2 PMID:17140416 -1.4.3.1 d-asparagine homo sapiens 8.3 8.3 1 PMID:31914658 -1.4.3.1 d-asparagine mus musculus 11.4 11.4 1 PMID:32553892 -1.4.3.1 d-aspartate bos taurus 0.725 0.45399999999999996 2 PMID:2901415 -1.4.3.1 d-aspartate caenorhabditis elegans 3.13 3.0999999999999996 2 PMID:17140416 -1.4.3.1 d-aspartate homo sapiens 81.3 81.3 1 PMID:31914658 -1.4.3.1 d-aspartate mus musculus 58.4 58.4 1 PMID:32553892 -1.4.3.1 d-aspartate thermomyces dupontii 123.0 123.0 1 PMID:30937498 -1.4.3.1 d-aspartate vanrija humicola 82.6 55.25 2 PMID:15115779;PMID:23132574 -1.4.3.1 d-glu caenorhabditis elegans 35.4 3.01 3 PMID:20564561 -1.4.3.1 d-glu vanrija humicola 2.6 2.6 1 PMID:26519738 -1.4.3.1 d-glutamate caenorhabditis elegans 5.31 3.71 4 PMID:17140416 -1.4.3.1 d-glutamate homo sapiens 11.3 11.3 1 PMID:31914658 -1.4.3.1 d-glutamate mus musculus 16.8 16.8 1 PMID:32553892 -1.4.3.1 d-glutamate thermomyces dupontii 217.0 217.0 1 PMID:30937498 -1.4.3.1 d-glutamate vanrija humicola 2.0 2.0 1 PMID:15115779 -1.4.3.1 d-glutamine thermomyces dupontii 144.0 144.0 1 PMID:30937498 -1.4.3.1 d-histidine homo sapiens 1.2 1.2 1 PMID:31914658 -1.4.3.1 d-histidine mus musculus 0.71 0.71 1 PMID:32553892 -1.4.3.1 d-proline homo sapiens 1.2 1.2 1 PMID:31914658 -1.4.3.1 d-proline mus musculus 5.5 5.5 1 PMID:32553892 -1.4.3.1 n-methyl-d-asp caenorhabditis elegans 84.5 6.04 3 PMID:20564561 -1.4.3.1 n-methyl-d-asparagine caenorhabditis elegans 6.13 4.5649999999999995 2 PMID:17140416 -1.4.3.1 n-methyl-d-aspartate caenorhabditis elegans 6.13 4.5649999999999995 2 PMID:17140416 -1.4.3.1 n-methyl-d-aspartate homo sapiens 73.6 73.6 1 PMID:31914658 -1.4.3.1 n-methyl-d-aspartate mus musculus 112.1 112.1 1 PMID:32553892 -1.4.3.1 n-methyl-d-aspartate thermomyces dupontii 155.0 155.0 1 PMID:30937498 -1.4.3.1 n-methyl-d-aspartate vanrija humicola 38.1 38.1 1 PMID:15115779 -1.4.3.1 o2 sus scrofa 635.0 172.0 3 PMID:17234685 -1.4.3.10 1,6-diaminohexane rhodococcus erythropolis 0.37 0.37 1 PMID:18183391 -1.4.3.10 2-hydroxyputrescine rhodococcus erythropolis 7.5 7.5 1 PMID:18183391 -1.4.3.10 cadaverine paenarthrobacter aurescens 1.72 1.72 1 PMID:24001036 -1.4.3.10 cadaverine rhodococcus erythropolis 3.9 3.9 1 PMID:18183391 -1.4.3.10 l-ornithine rhodococcus erythropolis 0.0198 0.0198 1 PMID:18183391 -1.4.3.10 putrescine paenarthrobacter aurescens 31.8 31.8 1 PMID:24001036 -1.4.3.10 putrescine rhodococcus erythropolis 26.4 25.95 6 PMID:18183391;PMID:21486042;PMID:25060191;PMID:32921059 -1.4.3.10 spermidine paenarthrobacter aurescens 0.29 0.29 1 PMID:24001036 -1.4.3.10 spermidine rhodococcus erythropolis 1.4 1.4 1 PMID:18183391 -1.4.3.10 spermine rhodococcus erythropolis 0.18 0.18 1 PMID:18183391 -1.4.3.11 l-glutamate streptomyces mobaraensis 0.164 0.164 1 PMID:32331723 -1.4.3.11 l-glutamate streptomyces sp. 85.8 69.5 2 PMID:15203041;PMID:22197816 -1.4.3.11 l-glutamate streptomyces sp. x-119-6 75.0 41.0 4 PMID:14769868 -1.4.3.11 l-glutamate streptomyces viridosporus 0.02 0.02 1 PMID:29663049 -1.4.3.12 (1r,2r)-2-aminocyclohexanol arthrobacter sp. tyut010-15 5.8 5.8 1 PMID:32789939 -1.4.3.12 (1r,2r)-2-aminocyclopentanol arthrobacter sp. tyut010-15 5.6 5.6 1 PMID:32789939 -1.4.3.12 (1r,2s)-1-amino-2-indanol arthrobacter sp. tyut010-15 4.9 4.9 1 PMID:32789939 -1.4.3.12 (1s,2r)-1-amino-2-indanol arthrobacter sp. tyut010-15 1.2 1.2 1 PMID:32789939 -1.4.3.12 (1s,2s)-2-aminocyclohexanol arthrobacter sp. tyut010-15 1.5 1.5 1 PMID:32789939 -1.4.3.12 (1s,2s)-2-aminocyclopentanol arthrobacter sp. tyut010-15 1.6 1.6 1 PMID:32789939 -1.4.3.12 (s)-1-aminotetraline microbacterium oxydans 5.72 5.72 1 PMID:23793344 -1.4.3.12 (s)-1-phenylethanamine microbacterium oxydans 4.15 4.15 1 * -1.4.3.12 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline erythrobacteraceae bacterium 0.135 0.135 1 PMID:32203655 -1.4.3.12 2-methyl-1,2,3,4-tetrahydroquinoline microbacterium oxydans 0.003 0.003 1 * -1.4.3.12 cyclohexylamine acinetobacter sp. yt-02 523.0 477.5 2 PMID:30524413 -1.4.3.12 cyclohexylamine microbacterium oxydans 11.48 11.48 1 PMID:23793344 -1.4.3.12 cyclooctanamine microbacterium oxydans 3.03 3.03 1 PMID:23793344 -1.4.3.12 l-valine ethyl ester microbacterium oxydans 0.64 0.64 1 * -1.4.3.13 1,5-diaminopentane homo sapiens 7290.0 7290.0 1 * -1.4.3.14 l-lysine scomber japonicus 203.0 203.0 1 PMID:25359785 -1.4.3.14 l-lysine trichoderma viride 65.5 60.95 4 PMID:32894626;PMID:33554108 -1.4.3.15 d-glutamate aspergillus ustus 0.0833 0.0833 1 * -1.4.3.16 3-hydroxy-erythro-l-aspartate escherichia coli 0.173 0.173 1 PMID:20600565 -1.4.3.16 fumarate bacillus subtilis 0.5 0.5 1 PMID:18959769 -1.4.3.16 l-aspartate arabidopsis thaliana 0.25 0.25 1 PMID:29650151 -1.4.3.16 l-aspartate bacillus subtilis 0.18 0.18 1 PMID:18959769 -1.4.3.16 l-aspartate escherichia coli 5.55 1.4335 4 PMID:20600565;PMID:2187483;PMID:8706750 -1.4.3.16 l-aspartate pseudomonas putida 10.6 10.6 1 * -1.4.3.16 l-aspartate sulfurisphaera tokodaii 1.05 1.05 2 PMID:23371294 -1.4.3.16 l-aspartate thermococcus litoralis 4.26 2.07 4 PMID:29143132 -1.4.3.16 n-acetyl-l-aspartate escherichia coli 0.0035 0.0035 1 PMID:20600565 -1.4.3.16 n-formyl-l-aspartate escherichia coli 0.0077 0.0077 1 PMID:20600565 -1.4.3.19 cyclopropylglycine bacillus subtilis 1.14 1.14 1 PMID:12627963 -1.4.3.19 d-ala bacillus subtilis 1.1 0.75 2 PMID:12627963;PMID:9827558 -1.4.3.19 d-alanine bacillus cereus 1.4 1.105 2 PMID:32993959 -1.4.3.19 d-alanine bacillus subtilis 0.92 0.92 1 PMID:17573175 -1.4.3.19 d-pro bacillus subtilis 3.5 2.4 2 PMID:12654003;PMID:9827558 -1.4.3.19 d-proline bacillus cereus 1.69 1.69 1 PMID:32993959 -1.4.3.19 d-proline bacillus subtilis 0.5 0.5 1 PMID:17573175 -1.4.3.19 gly bacillus subtilis 4.0 1.3 3 PMID:12627963;PMID:12654003;PMID:9827558 -1.4.3.19 glycine bacillus cereus 2.16 0.425 4 PMID:24223901;PMID:32993872;PMID:32993959 -1.4.3.19 glycine bacillus subtilis 4.1 1.85 10 PMID:17573175;PMID:19254749;PMID:19864430;PMID:24925096;PMID:31562850 -1.4.3.19 glycine marinomonas mediterranea 39.0 39.0 1 PMID:27637328 -1.4.3.19 glycine pseudoalteromonas luteoviolacea 6.0 6.0 1 PMID:29381339 -1.4.3.19 glyphosate bacillus cereus 0.87 0.095 3 PMID:24223901;PMID:32993872 -1.4.3.19 glyphosate bacillus subtilis 0.91 0.91 1 PMID:19864430 -1.4.3.19 n-ethylglycine bacillus subtilis 1.4 1.4 1 PMID:9827558 -1.4.3.19 o2 marinomonas mediterranea 93.0 93.0 1 PMID:27637328 -1.4.3.19 sarcosine bacillus cereus 0.98 0.98 1 * -1.4.3.19 sarcosine bacillus subtilis 4.2 1.1 4 PMID:12654003;PMID:17573175;PMID:24925096;PMID:9827558 -1.4.3.2 l-ala bungarus fasciatus 293.0 293.0 1 PMID:19393676 -1.4.3.2 l-alanine gloydius ussuriensis 26.89 26.89 1 PMID:17854853 -1.4.3.2 l-alanine rhodococcus opacus 2.1 1.375 2 PMID:12699695 -1.4.3.2 l-arg bungarus fasciatus 228.8 228.8 1 PMID:19393676 -1.4.3.2 l-arg rhizoctonia solani 0.13 0.13 1 PMID:27986991 -1.4.3.2 l-arginine gloydius ussuriensis 22.54 22.54 1 PMID:17854853 -1.4.3.2 l-arginine pseudomonas sp. 0.41 0.41 1 PMID:29511608 -1.4.3.2 l-asn bungarus fasciatus 84.08 84.08 1 PMID:19393676 -1.4.3.2 l-asp bungarus fasciatus 47.49 47.49 1 PMID:19393676 -1.4.3.2 l-asparagine gloydius ussuriensis 5.26 5.26 1 PMID:17854853 -1.4.3.2 l-gln bungarus fasciatus 430.4 430.4 1 PMID:19393676 -1.4.3.2 l-glu bungarus fasciatus 790.5 790.5 1 PMID:19393676 -1.4.3.2 l-glu hebeloma cylindrosporum 17.6 17.6 1 PMID:24077723 -1.4.3.2 l-glutamine hebeloma cylindrosporum 38.8 20.68 2 PMID:30631897 -1.4.3.2 l-his bungarus fasciatus 483.1 483.1 1 PMID:19393676 -1.4.3.2 l-histidine gloydius ussuriensis 4.15 4.15 1 PMID:17854853 -1.4.3.2 l-ile bungarus fasciatus 66.7 66.7 1 PMID:19393676 -1.4.3.2 l-isoleucine crotalus durissus terrificus 3421.0 3421.0 1 PMID:31078582 -1.4.3.2 l-isoleucine gloydius ussuriensis 6.33 6.33 1 PMID:17854853 -1.4.3.2 l-lactic acid rattus norvegicus 26.0 26.0 1 * -1.4.3.2 l-leu bungarus fasciatus 1025.05 1025.025 2 PMID:19393676;PMID:24738050 -1.4.3.2 l-leu calloselasma rhodostoma 3.3 3.3 1 PMID:24738050 -1.4.3.2 l-leu cerastes cerastes 24.4 24.4 1 PMID:25009089 -1.4.3.2 l-leu crotalus durissus cumanensis 1.8 1.8 1 PMID:24738050 -1.4.3.2 l-leu gloydius halys 31.1 31.1 1 PMID:15103157 -1.4.3.2 l-leu gloydius ussuriensis 48.22 48.22 1 PMID:24738050 -1.4.3.2 l-leu macrovipera lebetinus 52.0 52.0 1 PMID:24738050 -1.4.3.2 l-leu naja oxiana 47.98 47.98 1 PMID:24738050 -1.4.3.2 l-leu ophiophagus hannah 96.2 96.2 1 PMID:24738050 -1.4.3.2 l-leu rhizoctonia solani 0.13 0.13 1 PMID:27986991 -1.4.3.2 l-leu vipera berus berus 75.16 75.16 1 PMID:24738050 -1.4.3.2 l-leucine cerastes vipera 12.0 12.0 1 PMID:29898379 -1.4.3.2 l-leucine crotalus durissus cumanensis 1.8 1.8 1 PMID:23287728 -1.4.3.2 l-leucine crotalus durissus terrificus 5965.0 5965.0 1 PMID:31078582 -1.4.3.2 l-leucine gloydius ussuriensis 48.22 48.22 1 PMID:17854853 -1.4.3.2 l-leucine hebeloma cylindrosporum 45.3 23.81 2 PMID:30631897 -1.4.3.2 l-leucine macrovipera lebetinus 52.0 52.0 1 PMID:16828829 -1.4.3.2 l-leucine naja oxiana 47.98 47.98 1 PMID:18294891 -1.4.3.2 l-leucine ophiophagus hannah 86.6 86.6 1 PMID:2619759 -1.4.3.2 l-leucine rattus norvegicus 6.3 6.3 1 * -1.4.3.2 l-leucine methyl ester hebeloma cylindrosporum 27.8 15.200000000000001 2 PMID:30631897 -1.4.3.2 l-lys aspergillus oryzae 0.04 0.04 1 * -1.4.3.2 l-lys bungarus fasciatus 318.9 318.9 1 PMID:19393676 -1.4.3.2 l-lys myoxocephalus polyacanthocephalus 4.7 3.6500000000000004 2 PMID:19447190 -1.4.3.2 l-lys rhizoctonia solani 0.09 0.09 1 PMID:27986991 -1.4.3.2 l-lysine gloydius ussuriensis 10.51 10.51 1 PMID:17854853 -1.4.3.2 l-lysine platichthys stellatus 0.0302 0.015525 2 PMID:32974743 -1.4.3.2 l-lysine pseudomonas sp. 0.8 0.8 1 PMID:29511608 -1.4.3.2 l-lysine sebastes schlegelii 57.1 20.4 3 PMID:17140417;PMID:20728563 -1.4.3.2 l-met aspergillus oryzae 0.039 0.039 1 * -1.4.3.2 l-met bungarus fasciatus 589.93 589.615 2 PMID:19393676;PMID:24738050 -1.4.3.2 l-met calloselasma rhodostoma 1.65 1.65 1 PMID:24738050 -1.4.3.2 l-met cerastes cerastes 18.5 18.5 1 PMID:25009089 -1.4.3.2 l-met gloydius ussuriensis 24.13 24.13 1 PMID:24738050 -1.4.3.2 l-met macrovipera lebetinus 80.3 80.3 1 PMID:24738050 -1.4.3.2 l-met naja oxiana 66.26 66.26 1 PMID:24738050 -1.4.3.2 l-met ophiophagus hannah 65.6 65.6 1 PMID:24738050 -1.4.3.2 l-met rhizoctonia solani 0.08 0.08 1 PMID:27986991 -1.4.3.2 l-met vipera berus berus 74.2 74.2 1 PMID:24738050 -1.4.3.2 l-methionine crotalus durissus terrificus 7284.0 7284.0 1 PMID:31078582 -1.4.3.2 l-methionine gloydius ussuriensis 24.13 24.13 1 PMID:17854853 -1.4.3.2 l-methionine macrovipera lebetinus 80.3 40.254999999999995 2 PMID:16828829 -1.4.3.2 l-methionine naja oxiana 66.26 66.26 1 PMID:18294891 -1.4.3.2 l-orn rhizoctonia solani 0.1 0.1 1 PMID:27986991 -1.4.3.2 l-ornithine pseudomonas sp. 1.5 1.5 1 PMID:29511608 -1.4.3.2 l-phe aspergillus oryzae 0.039 0.039 1 * -1.4.3.2 l-phe bungarus fasciatus 142.62 142.61 2 PMID:19393676;PMID:24738050 -1.4.3.2 l-phe calloselasma rhodostoma 0.72 0.72 1 PMID:24738050 -1.4.3.2 l-phe cerastes cerastes 31.4 31.4 1 PMID:25009089 -1.4.3.2 l-phe gloydius ussuriensis 48.23 48.23 1 PMID:24738050 -1.4.3.2 l-phe naja oxiana 17.18 17.18 1 PMID:24738050 -1.4.3.2 l-phe ophiophagus hannah 54.1 54.1 1 PMID:24738050 -1.4.3.2 l-phe rhizoctonia solani 0.16 0.16 1 PMID:27986991 -1.4.3.2 l-phe vipera berus berus 28.5 28.5 1 PMID:24738050 -1.4.3.2 l-phenylalanine crotalus adamanteus 6.27 6.27 1 PMID:23772385 -1.4.3.2 l-phenylalanine crotalus atrox 6.78 6.78 1 PMID:23772385 -1.4.3.2 l-phenylalanine crotalus durissus terrificus 3483.0 3483.0 1 PMID:31078582 -1.4.3.2 l-phenylalanine gloydius ussuriensis 48.23 48.23 1 PMID:17854853 -1.4.3.2 l-phenylalanine hebeloma cylindrosporum 21.9 11.364999999999998 2 PMID:30631897 -1.4.3.2 l-phenylalanine naja oxiana 17.18 17.18 1 PMID:18294891 -1.4.3.2 l-phenylalanine proteus mirabilis 1.4 1.4 1 PMID:26552798 -1.4.3.2 l-phenylalanine trichoderma harzianum 0.025 0.0165 4 PMID:21781279 -1.4.3.2 l-phenylalanine methyl ester rhizoctonia solani 0.16 0.16 1 PMID:27986991 -1.4.3.2 l-propargylglycine crotalus adamanteus 9.62 9.62 1 PMID:23772385 -1.4.3.2 l-propargylglycine crotalus atrox 7.75 7.75 1 PMID:23772385 -1.4.3.2 l-trp bungarus fasciatus 98.82 98.82 2 PMID:19393676;PMID:24738050 -1.4.3.2 l-trp calloselasma rhodostoma 0.88 0.88 1 PMID:24738050 -1.4.3.2 l-trp gloydius ussuriensis 6.58 6.58 1 PMID:24738050 -1.4.3.2 l-trp macrovipera lebetinus 42.65 42.65 1 PMID:24738050 -1.4.3.2 l-trp naja oxiana 18.04 18.04 1 PMID:24738050 -1.4.3.2 l-trp ophiophagus hannah 32.1 32.1 1 PMID:24738050 -1.4.3.2 l-tryptophan crotalus durissus terrificus 3720.0 3720.0 1 PMID:31078582 -1.4.3.2 l-tryptophan gloydius ussuriensis 6.58 6.58 1 PMID:17854853 -1.4.3.2 l-tryptophan macrovipera lebetinus 42.6 42.6 1 PMID:16828829 -1.4.3.2 l-tryptophan naja oxiana 81.04 81.04 1 PMID:18294891 -1.4.3.2 l-tyr aspergillus oryzae 0.036 0.036 1 * -1.4.3.2 l-tyr bungarus fasciatus 100.6 100.6 1 PMID:19393676 -1.4.3.2 l-tyrosine gloydius ussuriensis 8.42 8.42 1 PMID:17854853 -1.4.3.2 l-valine gloydius ussuriensis 5.08 5.08 1 PMID:17854853 -1.4.3.20 l-lysine marinomonas mediterranea 0.34 0.28 2 PMID:24462691;PMID:26048732 -1.4.3.21 2-aminoethylpyridine huperzia serrata 2.9 2.9 1 PMID:22901898 -1.4.3.21 2-phenylethylamine arthrobacter globiformis 76.0 22.755 8 PMID:12537504;PMID:16142901;PMID:16566584;PMID:21984603 -1.4.3.21 2-phenylethylamine escherichia coli 12.4 12.4 1 PMID:20052994 -1.4.3.21 2-phenylethylamine paenarthrobacter aurescens 5.12 3.42 2 PMID:23225177 -1.4.3.21 3-aminomethylpyridine huperzia serrata 1.9 1.9 1 PMID:22901898 -1.4.3.21 4-aminomethylpyridine huperzia serrata 3.1 3.1 1 PMID:22901898 -1.4.3.21 4-fluorobenzylamine rhodococcus opacus 17.3 17.3 1 * -1.4.3.21 aminoacetone homo sapiens 1.46 1.46 1 PMID:22238597 -1.4.3.21 amylamine homo sapiens 4.33 4.33 1 PMID:22238597 -1.4.3.21 amylamine rhodococcus opacus 12.7 9.3 2 * -1.4.3.21 benzylamine arthrobacter globiformis 0.24 0.24 1 PMID:21984603 -1.4.3.21 benzylamine homo sapiens 3.42 3.42 1 PMID:22238597 -1.4.3.21 benzylamine huperzia serrata 1.4 1.4 1 PMID:22901898 -1.4.3.21 benzylamine ogataea angusta 8.1 0.066 3 PMID:20155950;PMID:23452079 -1.4.3.21 benzylamine rhodococcus opacus 12.1 12.1 1 * -1.4.3.21 benzylamine sus scrofa 198.0 198.0 1 PMID:6615797 -1.4.3.21 beta-phenylethylamine escherichia coli 20.77 13.68 7 PMID:11985492 -1.4.3.21 butylamine homo sapiens 6.31 6.31 1 PMID:22238597 -1.4.3.21 butylamine rhodococcus opacus 15.3 9.8 2 * -1.4.3.21 cadaverine huperzia serrata 1.0 1.0 1 PMID:22901898 -1.4.3.21 cadaverine paenarthrobacter aurescens 0.0619 0.0619 1 PMID:23225177 -1.4.3.21 cyclohexanemethylamine homo sapiens 5.36 5.36 1 PMID:22238597 -1.4.3.21 cysteamine homo sapiens 1.11 1.11 1 PMID:22238597 -1.4.3.21 dopamine homo sapiens 0.54 0.54 1 PMID:22238597 -1.4.3.21 dopamine rhodococcus opacus 1.9 1.9 1 * -1.4.3.21 ethanolamine rhodococcus opacus 3.3 3.3 1 * -1.4.3.21 ethylamine homo sapiens 6.12 6.12 1 PMID:22238597 -1.4.3.21 ethylamine ogataea angusta 20.0 20.0 2 PMID:16519513;PMID:23452079 -1.4.3.21 ethylamine rhodococcus opacus 7.2 7.2 1 * -1.4.3.21 histamine huperzia serrata 1.8 1.8 1 PMID:22901898 -1.4.3.21 histamine paenarthrobacter aurescens 5.91 3.185 2 PMID:23225177 -1.4.3.21 histamine rhodococcus opacus 13.2 13.2 1 * -1.4.3.21 isoamylamine homo sapiens 6.89 6.89 1 PMID:22238597 -1.4.3.21 isobutylamine homo sapiens 7.4 7.4 1 PMID:22238597 -1.4.3.21 methylamine homo sapiens 5.6 5.6 1 PMID:22238597 -1.4.3.21 methylamine ogataea angusta 6.2 2.1500000000000004 4 PMID:20155950 -1.4.3.21 methylamine rhodococcus opacus 0.4 0.4 1 * -1.4.3.21 o2 arthrobacter globiformis 110.0 1.24 3 PMID:12537504 -1.4.3.21 o2 lathyrus oleraceus 152.0 99.0 3 PMID:22258083 -1.4.3.21 o2 ogataea angusta 7.8 4.95 2 PMID:12186541 -1.4.3.21 octopamine rhodococcus opacus 3.5 3.5 1 * -1.4.3.21 phenethylamine homo sapiens 1.12 1.12 1 PMID:22238597 -1.4.3.21 phenylethylamine rhodococcus opacus 20.9 20.9 1 * -1.4.3.21 propylamine homo sapiens 5.8 5.8 1 PMID:22238597 -1.4.3.21 propylamine rhodococcus opacus 18.9 18.9 1 * -1.4.3.21 putrescine huperzia serrata 1.9 1.9 1 PMID:22901898 -1.4.3.21 putrescine lathyrus oleraceus 160.0 121.0 2 PMID:22258083 -1.4.3.21 spermidine huperzia serrata 2.3 2.3 1 PMID:22901898 -1.4.3.21 spermidine paenarthrobacter aurescens 0.0429 0.0429 1 PMID:23225177 -1.4.3.21 tryptamine lens culinaris 2.7 2.7 1 PMID:16054177 -1.4.3.21 tyramine arthrobacter globiformis 35.0 35.0 1 PMID:21984603 -1.4.3.21 tyramine lens culinaris 12.8 12.8 1 PMID:16054177 -1.4.3.21 tyramine paenarthrobacter aurescens 3.95 2.7750000000000004 2 PMID:23225177 -1.4.3.21 tyramine rhodococcus opacus 16.1 16.1 1 * -1.4.3.21 vanillylamine rhodococcus opacus 1.0 1.0 1 * -1.4.3.22 1,3-diaminopropane bos taurus 0.3 0.3 1 PMID:12529179 -1.4.3.22 1,3-diaminopropane homo sapiens 29220.0 29220.0 1 PMID:12072962 -1.4.3.22 1,4-methylhistamine aspergillus niger 68.0 68.0 1 PMID:7727530 -1.4.3.22 1,6-diaminohexane homo sapiens 17580.0 17580.0 1 PMID:12072962 -1.4.3.22 1,8-diaminooctane bos taurus 0.9 0.9 1 PMID:12529179 -1.4.3.22 1-aminobutane bos taurus 1.2 1.2 1 PMID:12529179 -1.4.3.22 1-aminononane bos taurus 0.4 0.4 1 PMID:12529179 -1.4.3.22 1-methylhistamine homo sapiens 6180.0 6180.0 1 PMID:12072962 -1.4.3.22 2-aminoethylpyridine lathyrus cicera 1.03 1.0 2 PMID:17521737 -1.4.3.22 2-aminomethylpyridine lathyrus cicera 0.47 0.315 2 PMID:14686927;PMID:17521737 -1.4.3.22 2-phenylethylamine arthrobacter globiformis 44.0 44.0 1 PMID:16846222 -1.4.3.22 2-phenylethylamine aspergillus niger 137.0 137.0 1 PMID:7727530 -1.4.3.22 2-phenylethylamine komagataella pastoris 11.2 11.2 1 PMID:16846222 -1.4.3.22 3-aminomethylpyridine lathyrus cicera 7.6 5.5649999999999995 2 PMID:17521737 -1.4.3.22 4-aminomethylpyridine lathyrus cicera 3.72 3.3600000000000003 2 PMID:17521737 -1.4.3.22 4-aminomethylpyridine lathyrus oleraceus 4.46 4.18 2 PMID:17521737 -1.4.3.22 4-dimethylaminomethylbenzylamine lens culinaris 0.000233 0.000233 1 PMID:8845363 -1.4.3.22 agmatine lathyrus cicera 45.9 26.2 2 PMID:14686927;PMID:17521737 -1.4.3.22 aminobutane aspergillus niger 132.0 132.0 1 PMID:7727530 -1.4.3.22 aminohexane aspergillus niger 159.0 159.0 1 PMID:7727530 -1.4.3.22 aminopentane aspergillus niger 142.0 142.0 1 PMID:7727530 -1.4.3.22 aminopropane aspergillus niger 132.0 132.0 1 PMID:7727530 -1.4.3.22 benzaldehyde bos taurus 0.35 0.35 1 PMID:17433047 -1.4.3.22 benzaldehyde euphorbia characias 0.17 0.17 1 PMID:17433047 -1.4.3.22 benzaldehyde lathyrus oleraceus 0.5 0.5 1 PMID:17433047 -1.4.3.22 benzaldehyde lens culinaris 1.0 0.95 2 PMID:17433047 -1.4.3.22 benzaldehyde sus scrofa 0.23 0.138 2 PMID:17433047 -1.4.3.22 benzylamine aspergillus niger 37.0 37.0 1 PMID:7727530 -1.4.3.22 benzylamine bos taurus 0.9 0.9 1 PMID:12529179 -1.4.3.22 benzylamine lathyrus cicera 4.45 4.075 2 PMID:14686927;PMID:17521737 -1.4.3.22 benzylamine lathyrus oleraceus 4.87 2.8 3 PMID:17521737;PMID:18582059 -1.4.3.22 cadaverine glycine max 498.0 498.0 1 PMID:8239662 -1.4.3.22 cadaverine homo sapiens 27180.0 27180.0 1 PMID:12072962 -1.4.3.22 cadaverine lathyrus cicera 159.0 115.9 2 PMID:14686927;PMID:17521737 -1.4.3.22 cadaverine sus scrofa 4.5 2.7 2 PMID:17433047 -1.4.3.22 dopamine aspergillus niger 135.0 135.0 1 PMID:7727530 -1.4.3.22 ethylenediamine homo sapiens 7560.0 7560.0 1 PMID:12072962 -1.4.3.22 histamine aspergillus niger 95.0 95.0 1 PMID:7727530 -1.4.3.22 histamine homo sapiens 8340.0 8340.0 1 PMID:12072962 -1.4.3.22 histamine lathyrus cicera 10.3 6.615 2 PMID:14686927;PMID:17521737 -1.4.3.22 l-lysine methyl ester homo sapiens 20700.0 20700.0 1 PMID:12072962 -1.4.3.22 n8-acetylspermidine bos taurus 0.6 0.6 1 PMID:12529179 -1.4.3.22 norepinephrine aspergillus niger 65.0 65.0 1 PMID:7727530 -1.4.3.22 o2 arthrobacter globiformis 53.0 53.0 1 PMID:16846222 -1.4.3.22 o2 homo sapiens 4.0 4.0 1 PMID:16846222 -1.4.3.22 o2 komagataella pastoris 12.6 12.6 1 PMID:16846222 -1.4.3.22 o2 lathyrus oleraceus 0.308 0.308 1 PMID:16846222 -1.4.3.22 octopamine aspergillus niger 122.0 122.0 1 PMID:7727530 -1.4.3.22 p-dimethylaminomethylbenzylamine homo sapiens 32880.0 32880.0 1 PMID:12072962 -1.4.3.22 phenylethylamine lathyrus cicera 30.9 23.35 2 PMID:17521737 -1.4.3.22 phenylethylamine lathyrus oleraceus 39.8 25.2 2 PMID:17521737 -1.4.3.22 putrescine euphorbia characias 13.3 13.3 1 PMID:17433047 -1.4.3.22 putrescine glycine max 163.0 163.0 1 PMID:8239662 -1.4.3.22 putrescine homo sapiens 28500.0 7.9 3 PMID:12072962;PMID:16846222;PMID:27063138 -1.4.3.22 putrescine lathyrus cicera 262.0 164.6 2 PMID:14686927;PMID:17521737 -1.4.3.22 putrescine lathyrus oleraceus 281.0 115.75 6 PMID:16846222;PMID:17433047;PMID:17521737;PMID:18582059 -1.4.3.22 putrescine lens culinaris 155.0 108.5 2 PMID:17433047;PMID:8845363 -1.4.3.22 serotonin aspergillus niger 136.0 136.0 1 PMID:7727530 -1.4.3.22 spermidine bos taurus 1.8 1.8 1 PMID:12529179 -1.4.3.22 spermidine glycine max 193.0 193.0 1 PMID:8239662 -1.4.3.22 spermidine homo sapiens 11220.0 11220.0 1 PMID:12072962 -1.4.3.22 spermidine lathyrus cicera 100.0 64.9 2 PMID:14686927;PMID:17521737 -1.4.3.22 spermidine lathyrus oleraceus 115.0 78.6 2 PMID:17521737 -1.4.3.22 spermine bos taurus 2.1 1.55 2 PMID:12529179;PMID:17433047 -1.4.3.22 spermine lathyrus cicera 28.3 19.5 2 PMID:14686927;PMID:17521737 -1.4.3.22 tryptamine aspergillus niger 100.0 100.0 1 PMID:7727530 -1.4.3.22 tyramine aspergillus niger 80.0 80.0 1 PMID:7727530 -1.4.3.22 tyramine lathyrus cicera 32.9 22.0 2 PMID:14686927;PMID:17521737 -1.4.3.22 tyramine lathyrus oleraceus 27.7 18.65 2 PMID:17521737 -1.4.3.23 1-methyl-l-tryptophan lentzea aerocolonigenes 0.0255 0.0255 1 PMID:15743957 -1.4.3.23 5-fluoro-l-tryptophan lentzea aerocolonigenes 0.239 0.239 1 PMID:15743957 -1.4.3.23 7-chloro-l-tryptophan lentzea aerocolonigenes 0.664 0.664 1 PMID:15743957 -1.4.3.23 l-trp lentzea aerocolonigenes 0.202 0.202 1 PMID:15743957 -1.4.3.3 cephalosporin c rhodotorula toruloides 4400.0 72.0 7 PMID:11130179;PMID:15058991;PMID:17145127;PMID:18330517;PMID:18594772 -1.4.3.3 cephalosporin c sus scrofa 39.0 39.0 1 PMID:15058991 -1.4.3.3 cephalosporin c trigonopsis variabilis 4300.0 55.0 7 PMID:15058991;PMID:18330517;PMID:18594772;PMID:19909828;PMID:7905327 -1.4.3.3 d-ala caenorhabditis elegans 14.9 14.9 1 PMID:20564561 -1.4.3.3 d-ala cyprinus carpio 190.0 190.0 1 PMID:15694590 -1.4.3.3 d-ala homo sapiens 5.5 5.35 2 PMID:16616139;PMID:17088322 -1.4.3.3 d-ala rhodotorula toruloides 4880.0 350.0 4 PMID:12021281;PMID:12354107;PMID:15058991;PMID:15450847 -1.4.3.3 d-ala sus scrofa 440.0 142.25 4 PMID:15058991;PMID:16751595;PMID:28592826 -1.4.3.3 d-ala trigonopsis variabilis 2740.0 1424.3 2 PMID:15058991;PMID:23157298 -1.4.3.3 d-alanine [candida] boidinii 80.0 80.0 1 PMID:17396222 -1.4.3.3 d-alanine cyprinus carpio 95.0 95.0 1 PMID:17396222 -1.4.3.3 d-alanine homo sapiens 14.7 7.34 6 PMID:10716694;PMID:17396222;PMID:18220846;PMID:22865246;PMID:31799256;PMID:32730563 -1.4.3.3 d-alanine rasamsonia emersonii 189.0 189.0 1 PMID:31420577 -1.4.3.3 d-alanine rattus norvegicus 27.0 27.0 1 PMID:21981077 -1.4.3.3 d-alanine rhodotorula toruloides 721.0 74.4 16 PMID:10821840;PMID:11130179;PMID:1348188;PMID:17145127;PMID:17396222;PMID:18220846;PMID:18330517;PMID:18343336;PMID:18594772;PMID:19066733;PMID:19694805;PMID:20498362;PMID:8100225 -1.4.3.3 d-alanine sus scrofa 12.7 10.0 5 PMID:11130179;PMID:11754736;PMID:17396222;PMID:18220846;PMID:7989339 -1.4.3.3 d-alanine trigonopsis variabilis 300.0 53.0 11 PMID:17396222;PMID:17466607;PMID:18220846;PMID:18330517;PMID:18594772;PMID:7905327;PMID:8100225;PMID:9771905 -1.4.3.3 d-arg caenorhabditis elegans 2.83 2.83 1 PMID:20564561 -1.4.3.3 d-arg sus scrofa 3.5 3.5 1 PMID:16751595 -1.4.3.3 d-arginine rasamsonia emersonii 45.6 45.6 1 PMID:31420577 -1.4.3.3 d-arginine rhodotorula toruloides 20.0 20.0 1 PMID:17145127 -1.4.3.3 d-asn rhodotorula toruloides 21.7 21.7 1 PMID:12021281 -1.4.3.3 d-asn trigonopsis variabilis 62.4 62.4 1 PMID:23157298 -1.4.3.3 d-asp homo sapiens 6.7 6.7 1 PMID:16616139 -1.4.3.3 d-asp rhodotorula toruloides 0.48 0.48 1 PMID:12021281 -1.4.3.3 d-asp sus scrofa 0.95 0.95 1 PMID:28592826 -1.4.3.3 d-aspartate homo sapiens 6.7 6.7 1 PMID:22865246 -1.4.3.3 d-aspartate rhodotorula toruloides 0.5 0.5 1 PMID:17145127 -1.4.3.3 d-cycloserine homo sapiens 0.77 0.77 1 PMID:29326945 -1.4.3.3 d-cysteine homo sapiens 8.6 5.8 2 PMID:29326945;PMID:31799256 -1.4.3.3 d-dopa homo sapiens 40.5 21.7 3 PMID:17303072;PMID:22865246;PMID:29326945 -1.4.3.3 d-gln rhodotorula toruloides 18.9 18.9 1 PMID:12021281 -1.4.3.3 d-glu rhodotorula toruloides 1.0 1.0 1 PMID:12021281 -1.4.3.3 d-glutamate rasamsonia emersonii 90.7 90.7 1 PMID:31420577 -1.4.3.3 d-his caenorhabditis elegans 1.51 1.51 1 PMID:20564561 -1.4.3.3 d-ile cyprinus carpio 76.7 76.7 1 PMID:15694590 -1.4.3.3 d-ile rubrobacter xylanophilus 23.0 23.0 1 PMID:25217016 -1.4.3.3 d-kynurenine homo sapiens 0.09 0.09 1 PMID:29326945 -1.4.3.3 d-leu cyprinus carpio 116.0 116.0 1 PMID:15694590 -1.4.3.3 d-leu rubrobacter xylanophilus 24.0 24.0 1 PMID:25217016 -1.4.3.3 d-leu trigonopsis variabilis 29.1 29.1 1 PMID:23157298 -1.4.3.3 d-lys cyprinus carpio 42.3 42.3 1 PMID:15694590 -1.4.3.3 d-lys sus scrofa 0.8 0.8 1 PMID:16751595 -1.4.3.3 d-lys trigonopsis variabilis 3.54 3.54 1 PMID:23157298 -1.4.3.3 d-met rhodotorula toruloides 76.7 76.7 1 PMID:12021281 -1.4.3.3 d-met sus scrofa 6.83 6.83 1 PMID:16751595 -1.4.3.3 d-met trigonopsis variabilis 80.5 80.5 1 PMID:23157298 -1.4.3.3 d-methionine rasamsonia emersonii 120.0 120.0 1 PMID:31420577 -1.4.3.3 d-methionine sus scrofa 143.0 143.0 1 PMID:7989339 -1.4.3.3 d-methionine trigonopsis variabilis 200.0 100.75 2 PMID:20193780 -1.4.3.3 d-phe caenorhabditis elegans 25.1 25.1 1 PMID:20564561 -1.4.3.3 d-phe cyprinus carpio 119.0 119.0 1 PMID:15694590 -1.4.3.3 d-phe sus scrofa 16.7 16.7 1 PMID:16751595 -1.4.3.3 d-phe trigonopsis variabilis 27.2 27.2 1 PMID:23157298 -1.4.3.3 d-phenylalanine homo sapiens 15.5 11.05 2 PMID:17303072;PMID:22865246 -1.4.3.3 d-phenylalanine rattus norvegicus 8.5 8.5 1 PMID:21981077 -1.4.3.3 d-phenylalanine sus scrofa 55.9 17.0 3 PMID:11754736;PMID:30333894;PMID:7989339 -1.4.3.3 d-pro cyprinus carpio 142.0 142.0 1 PMID:15694590 -1.4.3.3 d-pro homo sapiens 15.0 12.6 2 PMID:16616139;PMID:17088322 -1.4.3.3 d-pro rhodotorula toruloides 77.3 77.3 1 PMID:12021281 -1.4.3.3 d-pro sus scrofa 107.3 43.3 5 PMID:16751595;PMID:28592826 -1.4.3.3 d-proline homo sapiens 26.57 18.384999999999998 2 PMID:22865246;PMID:32730563 -1.4.3.3 d-proline rattus norvegicus 47.0 47.0 1 PMID:21981077 -1.4.3.3 d-proline sus scrofa 87.2 54.1 2 PMID:11754736;PMID:7989339 -1.4.3.3 d-ser caenorhabditis elegans 1.51 1.51 1 PMID:20564561 -1.4.3.3 d-ser cyprinus carpio 34.5 34.5 1 PMID:15694590 -1.4.3.3 d-ser homo sapiens 3.0 2.915 2 PMID:16616139;PMID:17088322 -1.4.3.3 d-ser sus scrofa 3.0 3.0 1 PMID:16751595 -1.4.3.3 d-ser trigonopsis variabilis 20.5 20.5 1 PMID:23157298 -1.4.3.3 d-serine homo sapiens 8.6 3.5 6 PMID:17303072;PMID:20521334;PMID:22865246;PMID:31799256;PMID:32730563 -1.4.3.3 d-serine rattus norvegicus 6.4 6.4 1 PMID:21981077 -1.4.3.3 d-serine sus scrofa 2.7 2.7 1 PMID:11754736 -1.4.3.3 d-thr rubrobacter xylanophilus 7.6 7.6 1 PMID:25217016 -1.4.3.3 d-thr trigonopsis variabilis 1.75 1.75 1 PMID:23157298 -1.4.3.3 d-trp trigonopsis variabilis 42.4 42.4 1 PMID:23157298 -1.4.3.3 d-tryptophan homo sapiens 3.2 3.2 1 PMID:22865246 -1.4.3.3 d-tryptophan rattus norvegicus 3.7 3.7 1 PMID:21981077 -1.4.3.3 d-tyr cyprinus carpio 117.0 117.0 1 PMID:15694590 -1.4.3.3 d-tyr rubrobacter xylanophilus 53.0 53.0 1 PMID:25217016 -1.4.3.3 d-tyr trigonopsis variabilis 22.5 22.5 1 PMID:23157298 -1.4.3.3 d-tyrosine homo sapiens 14.83 14.815000000000001 2 PMID:17303072;PMID:22865246 -1.4.3.3 d-val cyprinus carpio 170.0 170.0 1 PMID:15694590 -1.4.3.3 d-val rubrobacter xylanophilus 31.4 31.4 1 PMID:25217016 -1.4.3.3 d-val sus scrofa 2.5 2.5 1 PMID:16751595 -1.4.3.3 d-val trigonopsis variabilis 85.3 85.3 1 PMID:23157298 -1.4.3.3 d-valine rasamsonia emersonii 225.0 225.0 1 PMID:31420577 -1.4.3.3 d-valine rhodotorula toruloides 523.0 28.8 3 PMID:1348188;PMID:8100225 -1.4.3.3 d-valine sus scrofa 2.5 2.5 1 PMID:11754736 -1.4.3.3 d-valine trigonopsis variabilis 41.7 25.185000000000002 2 PMID:8100225 -1.4.3.3 gly homo sapiens 0.9 0.75 2 PMID:16616139;PMID:17088322 -1.4.3.3 glycine homo sapiens 0.9 0.9 1 PMID:22865246 -1.4.3.3 l-ala sus scrofa 9.4 4.745 2 PMID:28592826 -1.4.3.3 l-asp sus scrofa 0.89 0.89 1 PMID:28592826 -1.4.3.3 l-pro sus scrofa 6.71 0.7 3 PMID:28592826 -1.4.3.3 o2 rattus norvegicus 40.0 40.0 1 PMID:21981077 -1.4.3.3 o2 rhodotorula toruloides 350.0 350.0 2 PMID:12354107;PMID:15450847 -1.4.3.4 1,2,3,4-tetrahydronaphthalen-1-amine aspergillus niger 0.491 0.4165 2 PMID:28764963 -1.4.3.4 1-(4-bromophenyl)methanamine danio rerio 0.67 0.67 1 PMID:21354322 -1.4.3.4 1-(4-bromophenyl)methanamine rattus norvegicus 2.85 1.94 2 PMID:21819071 -1.4.3.4 1-(4-chlorophenyl)methanamine danio rerio 0.58 0.58 1 PMID:21354322 -1.4.3.4 1-(4-chlorophenyl)methanamine rattus norvegicus 2.0 1.365 2 PMID:21819071 -1.4.3.4 1-(4-fluorophenyl)methanamine danio rerio 0.25 0.25 1 PMID:21354322 -1.4.3.4 1-(4-fluorophenyl)methanamine rattus norvegicus 0.98 0.605 2 PMID:21819071 -1.4.3.4 1-(4-methoxyphenyl)methanamine danio rerio 0.14 0.14 1 PMID:21354322 -1.4.3.4 1-(4-methoxyphenyl)methanamine rattus norvegicus 0.45 0.3 2 PMID:21819071 -1.4.3.4 1-(4-methylphenyl)methanamine danio rerio 0.12 0.12 1 PMID:21354322 -1.4.3.4 1-(4-methylphenyl)methanamine rattus norvegicus 0.8 0.535 2 PMID:21819071 -1.4.3.4 1-[4-(trifluoromethyl)phenyl]methanamine danio rerio 1.57 1.57 1 PMID:21354322 -1.4.3.4 1-[4-(trifluoromethyl)phenyl]methanamine rattus norvegicus 13.52 9.545 2 PMID:21819071 -1.4.3.4 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine homo sapiens 0.241 0.18 3 PMID:15848762;PMID:2021654;PMID:2037155 -1.4.3.4 2,3-dihydro-1h-inden-1-amine aspergillus niger 2.882 2.0475000000000003 2 PMID:28764963 -1.4.3.4 2-phenylethylamine danio rerio 3.4 3.4 1 PMID:20079438 -1.4.3.4 2-phenylethylamine homo sapiens 3.82 3.82 1 PMID:16605246 -1.4.3.4 2-phenylethylamine rattus norvegicus 2.0 1.71 2 PMID:11754741;PMID:19883764 -1.4.3.4 3-phenyl-3-pyrroline bos taurus 834.0 834.0 1 PMID:12371853 -1.4.3.4 4-carboxybenzylamine danio rerio 0.088 0.088 1 PMID:21354322 -1.4.3.4 4-phenylbutylamine danio rerio 2.07 2.07 1 PMID:21354322 -1.4.3.4 benzylamine aspergillus niger 10.3 10.3 1 PMID:4634980 -1.4.3.4 benzylamine bos taurus 7.83 7.83 1 PMID:434814 -1.4.3.4 benzylamine danio rerio 0.08 0.079 2 PMID:20079438;PMID:21354322 -1.4.3.4 benzylamine homo sapiens 10.0 5.0 5 PMID:11049757;PMID:15848762;PMID:16605246;PMID:17401534;PMID:21978362 -1.4.3.4 benzylamine rattus norvegicus 8.3 0.3275 6 PMID:17401534;PMID:18424170;PMID:19883764;PMID:21819071 -1.4.3.4 dopamine danio rerio 4.03 4.03 1 PMID:21354322 -1.4.3.4 dopamine homo sapiens 0.249 0.249 1 PMID:11812236 -1.4.3.4 ethylamine aspergillus niger 11.1 11.1 1 PMID:4634980 -1.4.3.4 kynuramine danio rerio 1.25 1.25 1 PMID:21354322 -1.4.3.4 kynuramine homo sapiens 2.2 1.99 6 PMID:15848762;PMID:17393065;PMID:2037155;PMID:21978362;PMID:3932340 -1.4.3.4 kynuramine rattus norvegicus 2.485 2.48 3 PMID:17401534;PMID:19883764 -1.4.3.4 n-butylamine aspergillus niger 18.0 18.0 1 PMID:4634980 -1.4.3.4 o2 danio rerio 5.4 2.7465 2 PMID:20079438 -1.4.3.4 p-nitrobenzylamine homo sapiens 0.185 0.185 1 PMID:16605246 -1.4.3.4 p-nitrophenylethylamine homo sapiens 1.85 1.85 1 PMID:16605246 -1.4.3.4 p-trifluoromethyl-benzylamine homo sapiens 1.33 1.33 1 PMID:16605246 -1.4.3.4 phenethylamine homo sapiens 1.481 1.481 1 PMID:11812236 -1.4.3.4 phenylbutylamine homo sapiens 1.83 1.83 1 PMID:21978362 -1.4.3.4 phenylethylamine bos taurus 20.8 20.8 2 PMID:2037155;PMID:7066309 -1.4.3.4 phenylethylamine homo sapiens 3.1 1.4 5 PMID:15848762;PMID:17393065;PMID:17401534;PMID:21978362 -1.4.3.4 phenylethylamine rattus norvegicus 1.42 1.1585 2 PMID:17401534;PMID:19883764 -1.4.3.4 serotonin danio rerio 3.12 3.12 1 PMID:21354322 -1.4.3.4 serotonin homo sapiens 18.6 6.0 3 PMID:11812236;PMID:15848762;PMID:17401534 -1.4.3.4 serotonin rattus norvegicus 5.98 4.44 4 PMID:11754741;PMID:17401534;PMID:19883764 -1.4.3.4 tryptamine rattus norvegicus 3.5 3.5 1 PMID:11754741 -1.4.3.4 tyramine danio rerio 7.78 7.78 1 PMID:21354322 -1.4.3.4 tyramine homo sapiens 5.3 5.3 1 PMID:2021654 -1.4.3.4 tyramine rattus norvegicus 6.83 6.83 1 PMID:11754741 -1.4.3.5 5'-phospho-pyridoxyl-3-alanine sus scrofa 0.04 0.04 1 PMID:6697989 -1.4.3.5 5'-phospho-pyridoxyl-3-aminobenzoate sus scrofa 0.1 0.1 1 PMID:6697989 -1.4.3.5 5'-phospho-pyridoxyl-4-aminobutyrate sus scrofa 0.04 0.04 1 PMID:6697989 -1.4.3.5 5'-phospho-pyridoxyl-5-aminovalerate sus scrofa 0.035 0.035 1 PMID:6697989 -1.4.3.5 5'-phospho-pyridoxyl-aniline sus scrofa 0.01 0.01 1 PMID:6697989 -1.4.3.5 5'-phospho-pyridoxyl-p-aminonitrobenzene sus scrofa 0.1 0.1 1 PMID:6697989 -1.4.3.5 5'-phospho-pyridoxyl-p-aminophenol sus scrofa 0.004 0.004 1 PMID:6697989 -1.4.3.5 pyridoxal 5'-phosphate escherichia coli 33.0 33.0 1 PMID:7696318 -1.4.3.5 pyridoxamine 5'-phosphate escherichia coli 28.0 14.86 2 PMID:7696318;PMID:7860596 -1.4.3.5 pyridoxamine 5'-phosphate homo sapiens 0.2 0.2 1 PMID:12824491 -1.4.3.5 pyridoxamine 5'-phosphate oryctolagus cuniculus 0.103 0.103 1 PMID:18553334;PMID:6822512 -1.4.3.5 pyridoxamine 5'-phosphate saccharomyces cerevisiae 0.103 0.103 1 PMID:18553334;PMID:6822512 -1.4.3.5 pyridoxamine 5'-phosphate sus scrofa 0.009 0.009 1 PMID:6697989 -1.4.3.5 pyridoxine 5'-phosphate escherichia coli 0.76 0.225 8 PMID:11786019;PMID:12686112;PMID:28039149;PMID:31484724;PMID:34019876;PMID:7860596;PMID:9693059 -1.4.3.5 pyridoxine 5'-phosphate homo sapiens 0.19 0.121 4 PMID:12824491;PMID:27419045;PMID:32788630 -1.4.3.5 pyridoxine 5'-phosphate mycobacterium tuberculosis 0.01 0.01 1 PMID:22110704 -1.4.3.5 pyridoxine 5'-phosphate oryctolagus cuniculus 0.7 0.7 1 PMID:18553334;PMID:6822512 -1.4.3.5 pyridoxine 5'-phosphate saccharomyces cerevisiae 0.7 0.7 1 PMID:18553334;PMID:6822512 -1.4.3.5 pyridoxine 5'-phosphate sus scrofa 0.09 0.09 1 PMID:6697989 -1.4.4.2 glycine homo sapiens 0.047 0.019 7 PMID:24467211 -1.4.4.2 lipoamide trichomonas vaginalis 6.08 3.341 2 PMID:17158739 -1.4.4.2 rtvh1 protein trichomonas vaginalis 0.84 0.84 1 PMID:17158739 -1.4.4.2 rtvh2 protein trichomonas vaginalis 2.08 2.08 1 PMID:17158739 -1.4.5.1 d-2-amino butyrate escherichia coli b 15.7 15.7 1 PMID:6102989 -1.4.5.1 d-alanine escherichia coli b 15.5 15.5 1 PMID:6102989 -1.4.5.1 d-glutamine escherichia coli b 3.17 3.17 1 PMID:6102989 -1.4.5.1 d-methionine escherichia coli b 16.0 16.0 1 PMID:6102989 -1.4.5.1 d-phenylalanine escherichia coli b 14.7 14.7 1 PMID:6102989 -1.4.5.1 d-proline escherichia coli b 8.33 8.33 1 PMID:6102989 -1.4.5.1 d-serine escherichia coli b 5.33 5.33 1 PMID:6102989 -1.4.7.1 l-glutamate synechocystis sp. 3.67 3.67 1 PMID:12069605 -1.4.7.1 l-glutamine oryza sativa 137.0 137.0 1 PMID:16662307 -1.4.9.1 1,6-diaminohexane paracoccus denitrificans 17.0 17.0 1 PMID:11733518 -1.4.9.1 1,7-diaminoheptane paracoccus denitrificans 27.0 27.0 1 PMID:11733518 -1.4.9.1 1-aminopentane paracoccus denitrificans 17.0 17.0 1 PMID:11733518 -1.4.9.1 2,6-dichloroindophenol paracoccus denitrificans 1.5 1.5 1 PMID:10346915 -1.4.9.1 2-phenylethylamine paracoccus denitrificans 3.1 3.1 1 PMID:12974623 -1.4.9.1 amicyanin paracoccus versutus 74.0 3.1 3 PMID:18512962 -1.4.9.1 benzylamine paracoccus denitrificans 22.0 12.9 2 PMID:10346915;PMID:12974623 -1.4.9.1 butylamine paracoccus denitrificans 22.0 13.9 2 PMID:11733518;PMID:12974623 -1.4.9.1 cytochrome c-550 paracoccus versutus 2.3 2.3 1 PMID:8020493 -1.4.9.1 ethylamine paracoccus denitrificans 24.0 18.5 2 PMID:10346915;PMID:11733518 -1.4.9.1 k3fe(cn)6 paracoccus denitrificans 15.0 15.0 1 PMID:10346915 -1.4.9.1 methylamine paracoccus denitrificans 48.5 24.5 8 PMID:10346915;PMID:11733518;PMID:15734739;PMID:8448129 -1.4.9.1 methylamine paracoccus versutus 55.0 42.5 2 PMID:7918441 -1.4.9.1 phenazine ethosulfate paracoccus denitrificans 7.1 7.1 1 PMID:10346915 -1.4.9.1 phenethylamine paracoccus denitrificans 26.0 26.0 1 PMID:10346915 -1.4.9.1 propylamine paracoccus denitrificans 27.0 27.0 1 PMID:11733518 -1.4.9.2 azurin alcaligenes faecalis 91.0 77.5 2 PMID:7547967 -1.4.9.2 benzylamine alcaligenes faecalis 1.14 1.08 2 PMID:16403029 -1.4.9.2 dopamine alcaligenes faecalis 27.1 18.1 2 PMID:7669810 -1.4.99.6 2-oxo-4-methylvaleric acid ureibacillus thermosphaericus 5700.0 5700.0 1 PMID:23661083 -1.4.99.6 d-alanine pseudomonas aeruginosa 0.74 0.74 1 PMID:21378189 -1.4.99.6 d-arginine pseudomonas aeruginosa 204.0 85.55 4 PMID:19850617;PMID:20809650;PMID:20932054;PMID:21378189;PMID:25637657;PMID:28625766 -1.4.99.6 d-histidine pseudomonas aeruginosa 35.0 3.6 3 PMID:19850617;PMID:20809650;PMID:20932054;PMID:21378189;PMID:28625766 -1.4.99.6 d-leucine pseudomonas aeruginosa 55.0 6.4 3 PMID:20809650;PMID:25637657;PMID:28625766 -1.4.99.6 d-lysine pseudomonas aeruginosa 550.0 141.0 3 PMID:19850617;PMID:20809650;PMID:25637657;PMID:28625766 -1.4.99.6 d-methionine pseudomonas aeruginosa 190.0 154.0 3 PMID:19850617;PMID:20809650;PMID:25637657;PMID:28625766 -1.4.99.6 d-ornithine pseudomonas aeruginosa 6.2 6.2 1 PMID:19850617 -1.4.99.6 d-phenylalanine pseudomonas aeruginosa 75.0 5.3 3 PMID:19850617;PMID:20809650;PMID:21378189;PMID:28625766 -1.4.99.6 d-proline pseudomonas aeruginosa 0.97 0.97 1 PMID:21378189 -1.4.99.6 d-serine pseudomonas aeruginosa 0.8 0.8 1 PMID:21378189 -1.4.99.6 d-threonine pseudomonas aeruginosa 0.68 0.68 1 PMID:21378189 -1.4.99.6 d-tyrosine pseudomonas aeruginosa 23.0 3.6 3 PMID:19850617;PMID:20809650;PMID:21378189;PMID:28625766 -1.4.99.6 d-valine pseudomonas aeruginosa 0.78 0.78 1 PMID:21378189 -1.5.1.1 (4r)-delta1-pyrroline-4-hydroxy-2-carboxylate colwellia psychrerythraea 1.02 1.02 1 PMID:24649405 -1.5.1.1 1-piperideine-2-carboxylate azospirillum brasilense 166.0 163.75 2 PMID:24649405 -1.5.1.1 1-pyrroline-(4r)-hydroxy-2-carboxylate azospirillum brasilense 10.35 10.35 1 PMID:24649405 -1.5.1.1 1-pyrroline-2-carboxylate azospirillum brasilense 615.0 569.0 2 PMID:24649405 -1.5.1.1 delta1-piperidine-2-carboxylate azospirillum brasilense 165.8 163.65 2 PMID:24649405 -1.5.1.1 delta1-piperidine-2-carboxylate colwellia psychrerythraea 1.38 0.734 2 PMID:24649405 -1.5.1.1 delta1-pyrroline-(4r)-hydroxy-2-carboxylate azospirillum brasilense 10.35 10.35 1 PMID:24649405 -1.5.1.1 delta1-pyrroline-2-carboxylate azospirillum brasilense 615.0 569.15 2 PMID:24649405 -1.5.1.1 delta1-pyrroline-2-carboxylate colwellia psychrerythraea 124.5 67.425 2 PMID:24649405 -1.5.1.1 l-pipecolate azospirillum brasilense 3.7 2.5 3 PMID:24649405 -1.5.1.1 l-pipecolate colwellia psychrerythraea 0.02 0.02 1 PMID:24649405 -1.5.1.1 l-proline azospirillum brasilense 4.23 2.505 4 PMID:24649405 -1.5.1.1 l-proline colwellia psychrerythraea 1.09 0.54845 2 PMID:24649405 -1.5.1.11 2-oxobutanoate pecten maximus 526.0 526.0 1 PMID:18599075 -1.5.1.11 2-oxovalerate pecten maximus 272.0 272.0 1 PMID:18599075 -1.5.1.11 l-arg pecten maximus 640.0 640.0 2 PMID:18028427;PMID:18599075 -1.5.1.11 nadh pecten maximus 652.0 652.0 2 PMID:18028427;PMID:18599075 -1.5.1.11 pyruvate pecten maximus 775.0 775.0 2 PMID:18028427;PMID:18599075 -1.5.1.15 5,10-methenyltetrahydrofolate mycolicibacterium smegmatis 4.063 2.3754999999999997 2 PMID:32253341 -1.5.1.15 5,10-methylenetetrahydrofolate escherichia coli 2.2 0.47 3 PMID:29407039 -1.5.1.15 5,10-methylenetetrahydropteroylglutamate homo sapiens 12.4 6.95 2 PMID:29225823 -1.5.1.15 5,10-methylenetetrahydropteroylpentaglutamate homo sapiens 15.4 10.9 2 PMID:29225823 -1.5.1.15 l-5,10-methenyltetrahydrofolate acetobacterium woodii 1.58 1.58 1 PMID:6608524 -1.5.1.15 l-5,10-methylenetetrahydrofolate acetobacterium woodii 1.63 1.63 1 PMID:6608524 -1.5.1.15 nadh escherichia coli 18.2 2.2 3 PMID:29407039 -1.5.1.15 nadh mycolicibacterium smegmatis 6.095 3.7085 2 PMID:32253341 -1.5.1.17 glycine arenicola marina 176.4 176.4 1 PMID:24066861 -1.5.1.17 l-alanine arenicola marina 1084.6 1084.6 1 PMID:24066861 -1.5.1.18 (r,r)-(-)-pseudoephedrine arthrobacter sp. ts-15 2.06 2.06 1 PMID:31900306 -1.5.1.18 (r,s)-(-)-ephedrine arthrobacter sp. ts-15 2.62 2.62 1 PMID:31900306 -1.5.1.18 1,2-indandione arthrobacter sp. ts-15 31.11 31.11 1 * -1.5.1.18 1,2-naphthoquinone arthrobacter sp. ts-15 7.94 7.94 1 * -1.5.1.18 1-phenyl-1,3-butanedione arthrobacter sp. ts-15 15.37 15.37 1 * -1.5.1.18 1-phenylpropan-1,2-dione arthrobacter sp. ts-15 30.43 30.43 1 * -1.5.1.18 2-aminoacetophenone arthrobacter sp. ts-15 27.13 27.13 1 * -1.5.1.18 ethyl 2-chlorobenzoylacetate arthrobacter sp. ts-15 37.38 37.38 1 * -1.5.1.18 methylbenzoyl formate arthrobacter sp. ts-15 40.05 40.05 1 * -1.5.1.18 phenylglyoxal arthrobacter sp. ts-15 9.49 9.49 1 * -1.5.1.2 1-pyrroline-5-carboxylate homo sapiens 61.3 31.0 5 PMID:28258219;PMID:33771508 -1.5.1.2 1-pyrroline-5-carboxylate mycobacterium tuberculosis 451.7 387.3 3 PMID:16199181 -1.5.1.2 1-pyrroline-5-carboxylate trypanosoma cruzi 1.0 1.0 1 PMID:32315030 -1.5.1.2 3,4-dehydro-l-proline homo sapiens 10.0 10.0 1 PMID:16600630 -1.5.1.2 l-proline mycobacterium tuberculosis 212.8 212.8 1 PMID:16199181 -1.5.1.2 nadh arabidopsis thaliana 3049.0 3049.0 1 PMID:24467670 -1.5.1.2 nadh homo sapiens 218.0 47.9 3 PMID:28258219;PMID:33771508 -1.5.1.2 nadh medicago truncatula 2.972 2.972 1 PMID:26579138 -1.5.1.2 nadh mycobacterium tuberculosis 4170.0 2240.1 2 PMID:16199181 -1.5.1.2 nadh streptococcus pyogenes 620.0 620.0 1 PMID:21938400 -1.5.1.2 nadh zymomonas mobilis subsp. mobilis 27.0 27.0 1 PMID:34331182 -1.5.1.2 nadp+ homo sapiens 55.0 55.0 1 PMID:16730026 -1.5.1.2 nadp+ mycobacterium tuberculosis 137.9 137.9 1 PMID:16199181 -1.5.1.2 nadph arabidopsis thaliana 694.0 694.0 1 PMID:24467670 -1.5.1.2 nadph homo sapiens 74.0 24.0 3 PMID:28258219;PMID:33771508 -1.5.1.2 nadph medicago truncatula 1.113 1.113 1 PMID:26579138 -1.5.1.2 nadph mycobacterium tuberculosis 4000.0 2160.8 2 PMID:16199181 -1.5.1.2 nadph streptococcus pyogenes 340.0 340.0 1 PMID:21938400 -1.5.1.2 nadph trypanosoma cruzi 1.99 1.99 1 PMID:32315030 -1.5.1.2 nadph zymomonas mobilis subsp. mobilis 6.0 6.0 1 PMID:34331182 -1.5.1.2 pyrroline-5-carboxylate hordeum vulgare 1270.0 1270.0 1 PMID:16664571 -1.5.1.20 methylenetetrahydrofolate escherichia coli 2.2 2.2 1 PMID:15865426 -1.5.1.20 methylenetetrahydrofolate sus scrofa 50.0 50.0 1 PMID:6352699 -1.5.1.20 nadh escherichia coli 55.0 23.5 3 PMID:10201405;PMID:19610625 -1.5.1.20 nadh leishmania major 87.0 69.5 2 PMID:17032644 -1.5.1.20 nadh sus scrofa 160.0 160.0 1 PMID:3702701 -1.5.1.20 nadph leishmania major 140.0 107.0 2 PMID:17032644 -1.5.1.20 nadph sus scrofa 160.0 160.0 1 PMID:6352699 -1.5.1.21 1-piperideine-2-carboxylate pseudomonas aeruginosa 35.3 35.3 1 PMID:24649405 -1.5.1.21 1-pyrroline-(4r)-hydroxy-2-carboxylate pseudomonas aeruginosa 14.5 14.5 1 PMID:24649405 -1.5.1.21 1-pyrroline-2-carboxylate pseudomonas aeruginosa 41.67 41.67 1 PMID:24649405 -1.5.1.21 l-pipecolate pseudomonas aeruginosa 2.25 2.25 1 PMID:24649405 -1.5.1.21 l-proline pseudomonas aeruginosa 3.42 3.42 1 PMID:24649405 -1.5.1.21 trans-3-hydroxy-l-proline pseudomonas aeruginosa 4.53 4.53 1 PMID:24649405 -1.5.1.22 2-ketobutyrate marphysa sanguinea 23.2 22.485 2 * -1.5.1.22 d-strombine marphysa sanguinea 4.99 4.99 1 * -1.5.1.22 gly marphysa sanguinea 50.08 50.08 1 * -1.5.1.22 l-ala marphysa sanguinea 51.7 51.7 1 * -1.5.1.22 l-ser marphysa sanguinea 23.64 23.64 1 * -1.5.1.22 meso-alanopine marphysa sanguinea 5.12 5.12 1 * -1.5.1.22 nad+ marphysa sanguinea 3.96 3.91 2 * -1.5.1.22 nadh marphysa sanguinea 44.7 44.14 2 * -1.5.1.22 oxaloacetate marphysa sanguinea 44.25 43.455 2 * -1.5.1.22 pyruvate marphysa sanguinea 47.78 47.555 2 * -1.5.1.25 delta1-piperideine 2-carboxylate homo sapiens 4.4 4.4 1 PMID:25931162 -1.5.1.25 delta1-pyrrolidine 2-carboxylate homo sapiens 6.6 6.6 1 PMID:25931162 -1.5.1.25 delta2-thiazoline-2-carboxylate homo sapiens 1.7 1.7 1 PMID:25931162 -1.5.1.25 s-(2-aminoethyl)-l-cysteine ketimine homo sapiens 0.2 0.2 1 PMID:25931162 -1.5.1.3 10-formyl-dihydrofolate escherichia coli 4.6 4.6 1 PMID:29799386 -1.5.1.3 7,8-dihydrofolate bacillus anthracis 9.3 9.3 1 PMID:20882962 -1.5.1.3 7,8-dihydrofolate brugia malayi 2.2 1.8 2 PMID:27544923;PMID:29787565 -1.5.1.3 7,8-dihydrofolate cricetulus griseus 0.65 0.65 1 PMID:9056490 -1.5.1.3 7,8-dihydrofolate enterococcus faecium 133.0 116.5 2 PMID:5021603;PMID:5687716 -1.5.1.3 7,8-dihydrofolate escherichia coli 37.0 13.7 19 PMID:15944418;PMID:16510443;PMID:17264073;PMID:20043879;PMID:20045086;PMID:23672258;PMID:29799386;PMID:3052577;PMID:31095809;PMID:9989225 -1.5.1.3 7,8-dihydrofolate gallus gallus 5.0 5.0 1 PMID:4379915 -1.5.1.3 7,8-dihydrofolate glycine max 0.95 0.95 1 PMID:820266 -1.5.1.3 7,8-dihydrofolate haloarcula japonica 20.7 3.25 6 PMID:28349498 -1.5.1.3 7,8-dihydrofolate haloferax volcanii 3.14 3.14 1 PMID:8365406 -1.5.1.3 7,8-dihydrofolate homo sapiens 26.0 10.0 6 PMID:10683342;PMID:17868689;PMID:18566481;PMID:23545530;PMID:4396284;PMID:7275974 -1.5.1.3 7,8-dihydrofolate human gammaherpesvirus 8 7.0 7.0 1 PMID:10683342 -1.5.1.3 7,8-dihydrofolate lacticaseibacillus casei 4.0 3.5 2 PMID:10886;PMID:4401226 -1.5.1.3 7,8-dihydrofolate leishmania major 29.0 29.0 1 PMID:8144647 -1.5.1.3 7,8-dihydrofolate methylorubrum extorquens 17.0 12.1 2 PMID:30364315 -1.5.1.3 7,8-dihydrofolate moritella profunda 39.6 18.7 9 PMID:20726028 -1.5.1.3 7,8-dihydrofolate mus musculus 4.67 2.4565 2 PMID:7287696 -1.5.1.3 7,8-dihydrofolate mycobacterium avium 20.5 20.5 1 PMID:17542991 -1.5.1.3 7,8-dihydrofolate mycobacterium tuberculosis 2.3 1.95 2 PMID:21138249 -1.5.1.3 7,8-dihydrofolate plasmodium falciparum 88.0 44.62 2 PMID:17451822;PMID:9371090 -1.5.1.3 7,8-dihydrofolate plasmodium knowlesi 15.9 15.9 1 PMID:30114522 -1.5.1.3 7,8-dihydrofolate pneumocystis carinii 284.0 235.0 3 PMID:19196009;PMID:23545530;PMID:8425104 -1.5.1.3 7,8-dihydrofolate pneumocystis jirovecii 53.0 29.5 2 PMID:19196009;PMID:23545530 -1.5.1.3 7,8-dihydrofolate saccharomyces cerevisiae 11.5 11.5 1 PMID:4403556 -1.5.1.3 7,8-dihydrofolate schistosoma mansoni 130.0 130.0 1 PMID:28288799 -1.5.1.3 7,8-dihydrofolate stenotrophomonas maltophilia 123.0 123.0 1 PMID:17847703 -1.5.1.3 7,8-dihydrofolate sus scrofa 13.5 13.5 1 PMID:500653 -1.5.1.3 7,8-dihydrofolate thermotoga maritima 0.06 0.06 1 PMID:23672258 -1.5.1.3 7,8-dihydrofolate trypanosoma brucei 5.0 4.055 2 PMID:21650210;PMID:8538681 -1.5.1.3 7,8-dihydrofolate wuchereria bancrofti 7.4 7.4 1 PMID:29787565 -1.5.1.3 acetylpyridine adenine nucleotide escherichia coli 2.0 2.0 1 PMID:3052577 -1.5.1.3 dihydrofolate escherichia coli 18.4 18.4 1 PMID:20040594 -1.5.1.3 dihydrofolate homo sapiens 51.0 51.0 1 PMID:20393885 -1.5.1.3 dihydrofolate moritella japonica 144.0 144.0 1 PMID:20040594 -1.5.1.3 dihydrofolate moritella yayanosii 83.8 83.8 1 PMID:20040594 -1.5.1.3 dihydrofolate photobacterium profundum 156.0 156.0 1 PMID:20040594 -1.5.1.3 dihydrofolate shewanella violacea 90.0 90.0 1 PMID:20040594 -1.5.1.3 dihydrofolate streptococcus pneumoniae 31.5 31.5 1 PMID:19950924 -1.5.1.3 folate homo sapiens 1.08 1.08 1 PMID:7275974 -1.5.1.3 folate lacticaseibacillus casei 0.02 0.02 1 PMID:10886 -1.5.1.3 nadp+ schistosoma mansoni 35.9 35.9 1 PMID:28288799 -1.5.1.3 nadph bos taurus 5.1 5.1 1 PMID:15895994 -1.5.1.3 nadph escherichia coli 28.1 10.5 8 PMID:20040594;PMID:23672258;PMID:29799386;PMID:3052577;PMID:4401227 -1.5.1.3 nadph geobacillus stearothermophilus 218.0 218.0 1 PMID:16114879 -1.5.1.3 nadph haloarcula japonica 20.3 2.8 7 PMID:28349498 -1.5.1.3 nadph homo sapiens 51.0 38.5 2 PMID:20393885;PMID:23545530 -1.5.1.3 nadph lacticaseibacillus casei 3.67 3.67 1 * -1.5.1.3 nadph moritella japonica 109.0 109.0 1 PMID:20040594 -1.5.1.3 nadph moritella yayanosii 80.3 80.3 1 PMID:20040594 -1.5.1.3 nadph mycobacterium avium 26.8 26.8 1 PMID:17542991 -1.5.1.3 nadph photobacterium profundum 150.5 150.5 1 PMID:20040594 -1.5.1.3 nadph plasmodium falciparum 60.9 60.9 1 PMID:17320089 -1.5.1.3 nadph pneumocystis carinii 235.0 235.0 1 PMID:23545530 -1.5.1.3 nadph pneumocystis jirovecii 6.0 6.0 1 PMID:23545530 -1.5.1.3 nadph shewanella violacea 86.8 86.8 1 PMID:20040594 -1.5.1.30 cibacron marine bacillus subtilis 0.7 0.7 1 PMID:16752898 -1.5.1.30 fad homo sapiens 0.3 0.3 1 PMID:10620517 -1.5.1.30 fad microcebus murinus 0.061 0.061 1 PMID:32246827 -1.5.1.30 fad streptomyces viridifaciens 51.0 51.0 1 PMID:9287340 -1.5.1.30 fmn bacillus subtilis 60.0 60.0 1 PMID:16752898 -1.5.1.30 fmn cereibacter sphaeroides 54.38 54.38 1 PMID:17846764 -1.5.1.30 fmn escherichia coli 1.9 1.7999999999999998 2 PMID:15882995 -1.5.1.30 fmn homo sapiens 0.099 0.099 1 PMID:10620517 -1.5.1.30 fmn streptomyces viridifaciens 45.0 45.0 1 PMID:9287340 -1.5.1.30 fmn vibrio harveyi 37.5 36.0 3 PMID:18067321;PMID:8206832 -1.5.1.30 nadph bacillus subtilis 70.0 70.0 1 PMID:16752898 -1.5.1.30 nadph corynebacterium glutamicum 0.036 0.0321 2 PMID:27474351 -1.5.1.30 nadph streptomyces viridifaciens 62.0 62.0 1 PMID:9287340 -1.5.1.30 nadph vibrio harveyi 69.5 53.8 3 PMID:10869187;PMID:22650604 -1.5.1.30 oxidized riboflavin homo sapiens 0.3 0.3 1 PMID:10620517 -1.5.1.30 riboflavin streptomyces viridifaciens 6.7 6.7 1 PMID:9287340 -1.5.1.33 7,8-dihydrobiopterin agrobacterium fabrum 4.7 4.7 1 PMID:32482721 -1.5.1.33 7,8-dihydromonapterin agrobacterium fabrum 2.3 2.3 1 PMID:32482721 -1.5.1.33 7,8-dihydroneopterin agrobacterium fabrum 2.4 2.4 1 PMID:32482721 -1.5.1.33 biopterin leishmania tarentolae 0.23 0.23 1 PMID:9490050 -1.5.1.33 dihydrobiopterin leishmania major 0.57 0.57 1 PMID:21239486 -1.5.1.33 dihydrobiopterin trypanosoma brucei 4.7 2.375 2 PMID:16968221;PMID:21239486 -1.5.1.33 dihydrobiopterin trypanosoma brucei brucei 0.12 0.12 1 PMID:32496217 -1.5.1.33 quinonoid 6,7-dimethyl-7,8-dihydropterin leishmania major 0.44 0.44 1 PMID:21239486 -1.5.1.33 quinonoid 6,7-dimethyl-7,8-dihydropterin trypanosoma brucei 0.43 0.43 1 PMID:21239486 -1.5.1.33 quinonoid dihydrobiopterin leishmania major 1.84 1.84 1 PMID:21239486 -1.5.1.33 quinonoid dihydrobiopterin trypanosoma brucei 0.54 0.54 1 PMID:21239486 -1.5.1.34 2-amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridine homo sapiens 510.0 510.0 1 PMID:7317032 -1.5.1.34 nadh homo sapiens 280.0 148.5 2 PMID:6870900;PMID:8262916 -1.5.1.34 nadh rattus norvegicus 158.0 157.0 2 PMID:1898002 -1.5.1.34 nadph homo sapiens 20.0 20.0 1 PMID:8262916 -1.5.1.34 quinoid 2-amino-4-hydroxy-6,7-dimethyl-7,8-dihydropteridine homo sapiens 162.0 162.0 1 PMID:8262916 -1.5.1.34 quinoid 6-methyl-7,8-dihydropterin homo sapiens 227.0 129.0 2 * -1.5.1.34 quinoid 7,8-dihydrobiopterin homo sapiens 44.5 30.75 2 PMID:8262916 -1.5.1.34 quinoid 7,8-dihydropterin homo sapiens 44.5 44.5 1 * -1.5.1.34 quinoid dihydrobiopterin rattus norvegicus 153.0 88.0 2 PMID:8631945;PMID:9235988 -1.5.1.34 quinonoid 6,7-dimethyl-7,8-dihydropteridine rattus norvegicus 153.0 153.0 1 PMID:9235988 -1.5.1.34 quinonoid 7,8-(6h)-dihydrobiopterin homo sapiens 113.0 26.299999999999997 4 PMID:3956486 -1.5.1.34 quinonoid 7,8-(6h)-dihydropterin homo sapiens 113.0 26.299999999999997 4 PMID:3956486 -1.5.1.34 quinonoid dihydrobiopterin pseudomonas sp. 20.0 20.0 1 PMID:8429 -1.5.1.34 tetrahydrobiopterin homo sapiens 200.0 200.0 1 PMID:7317032 -1.5.1.36 fad acinetobacter baylyi 56.0 56.0 1 PMID:25116410 -1.5.1.36 fad escherichia coli 178.0 109.0 2 PMID:12809507 -1.5.1.36 fmn acinetobacter baylyi 7.8 7.8 1 PMID:25116410 -1.5.1.36 fmn photobacterium leiognathi 1.7 1.7 1 PMID:20836540 -1.5.1.36 nadh acinetobacter baylyi 64.0 64.0 1 PMID:25116410 -1.5.1.36 nadh corynebacterium glutamicum 0.0357 0.0302 2 PMID:27474351 -1.5.1.36 nadh escherichia coli 178.0 109.0 2 PMID:12809507 -1.5.1.36 riboflavin acinetobacter baylyi 21.0 21.0 1 PMID:25116410 -1.5.1.37 fad paraburkholderia phenoliruptrix 16.6 16.6 1 PMID:12700257 -1.5.1.37 fad pseudomonas protegens pf-5 65.0 65.0 1 PMID:17921302 -1.5.1.37 fad pseudomonas putida 128.0 128.0 1 PMID:23524667 -1.5.1.37 fad streptomyces globisporus 4.5 4.5 1 PMID:19817865 -1.5.1.37 fmn paraburkholderia phenoliruptrix 18.5 18.5 1 PMID:12700257 -1.5.1.37 fmn pseudomonas protegens pf-5 72.4 72.4 1 PMID:17921302 -1.5.1.37 fmn pseudomonas putida 283.0 283.0 1 PMID:23524667 -1.5.1.37 lumiflavin pseudomonas protegens pf-5 66.5 66.5 1 PMID:17921302 -1.5.1.37 nadh paraburkholderia phenoliruptrix 30.1 21.0 2 PMID:12700257 -1.5.1.37 nadh pseudomonas protegens pf-5 62.6 62.6 1 PMID:17921302 -1.5.1.37 nadh streptomyces globisporus 3.1 3.1 1 PMID:19817865 -1.5.1.37 riboflavin pseudomonas protegens pf-5 68.2 68.2 1 PMID:17921302 -1.5.1.38 fmn escherichia coli 4.25 4.25 1 PMID:29979040 -1.5.1.38 nadph bacillus cereus 1.5 1.5 1 PMID:26415543 -1.5.1.38 nadph vibrio harveyi 34.0 28.9 2 PMID:22650604;PMID:880288 -1.5.1.39 fmn paracoccus denitrificans 56.0 56.0 1 PMID:30977245 -1.5.1.39 nadh escherichia coli 3.0 3.0 1 PMID:30171650 -1.5.1.39 nadph escherichia coli 3.0 3.0 1 PMID:30171650 -1.5.1.40 1,5-dihydro-8-hydroxy-5-deazaflavin methanococcus vannielii 7.37 7.37 1 PMID:7391030 -1.5.1.40 1-aminoethylnicotinamide thermobifida fusca 0.0233 0.0233 1 PMID:34557329 -1.5.1.40 1-benzyl-3-acetylpyridine thermobifida fusca 0.0042 0.0042 1 PMID:34557329 -1.5.1.40 1-benzylnicotinamide thermobifida fusca 0.0045 0.0045 1 PMID:34557329 -1.5.1.40 1-ethylnicotinamide thermobifida fusca 0.0073 0.0073 1 PMID:34557329 -1.5.1.40 1-hydroxyethylnicotinamide thermobifida fusca 0.0233 0.0233 1 PMID:34557329 -1.5.1.40 1-hydroxypropylnicotinamide thermobifida fusca 0.0042 0.0042 1 PMID:34557329 -1.5.1.40 1-propylnicotinamide thermobifida fusca 0.0015 0.0015 1 PMID:34557329 -1.5.1.40 5'-o-methyl-7,8-didemethyl-8-hydroxyflavin streptomyces griseus 6.5 6.5 1 PMID:2492438 -1.5.1.40 5-deaza-8-hydroxyisoalloxazine streptomyces griseus 4.4 4.4 1 PMID:2492438 -1.5.1.40 7,8-didemethyl-8-hydroxy-5-deazariboflavin 5'-phosphate streptomyces griseus 35.57 35.57 1 PMID:2492438 -1.5.1.40 8-hydroxy-5-deazaflavin methanococcus vannielii 175.0 175.0 1 PMID:7391030 -1.5.1.40 8-hydroxypyrimido[4,5-b]-2,4-(3h,10h)-dione streptomyces griseus 10.23 10.23 1 PMID:2492438 -1.5.1.40 coenzyme f0 streptomyces griseus 12.15 12.15 1 PMID:2492438 -1.5.1.40 coenzyme f420 streptomyces griseus 17.22 17.22 1 PMID:2492438 -1.5.1.40 nadp+ methanococcus vannielii 7.37 7.37 1 PMID:7391030 -1.5.1.40 nadph archaeoglobus fulgidus 5.41 5.41 3 PMID:26811861;PMID:28955995 -1.5.1.40 nadph methanococcus vannielii 175.0 175.0 1 PMID:7391030 -1.5.1.40 nadph thermobifida fusca 3.3 2.75 2 PMID:28411200 -1.5.1.40 oxidized coenzyme f420 archaeoglobus fulgidus 5.3 5.285 2 PMID:26811861;PMID:28955995 -1.5.1.40 reduced coenzyme f420 streptomyces griseus 3.0 3.0 1 PMID:2492438 -1.5.1.41 nadh corynebacterium glutamicum 0.603 0.547 3 PMID:27474351 -1.5.1.41 nadph corynebacterium glutamicum 0.069 0.065 2 PMID:27474351 -1.5.1.42 fad pseudomonas putida 128.0 128.0 1 PMID:23524667 -1.5.1.42 fmn nocardioides sp. pd653 66.74 66.74 1 PMID:32913414 -1.5.1.42 fmn pseudomonas putida 283.0 283.0 1 PMID:23524667 -1.5.1.42 nadh nocardioides sp. pd653 66.74 66.74 1 PMID:32913414 -1.5.1.42 nadph vibrio harveyi 15.5 15.5 1 PMID:880288 -1.5.1.47 7,8-dihydromethanopterin methylorubrum extorquens 1.5 1.5 1 PMID:30364315 -1.5.1.47 dihydrosarcinapterin hyphomicrobium nitrativorans 2.9 2.9 1 PMID:30364315 -1.5.1.47 dihydrosarcinapterin methylobacterium nodulans 1.6 1.6 1 PMID:30364315 -1.5.1.47 dihydrosarcinapterin methylorubrum extorquens 1.5 1.5 1 PMID:30364315 -1.5.1.48 1-methyl-3,4-dihydroisoquinoline streptomyces sp. gf3587 0.189 0.189 1 PMID:27547270 -1.5.1.48 2-methyl-1-pyrroline streptomyces sp. gf3587 0.351 0.351 1 PMID:27547270 -1.5.1.48 2-methyl-3,4-dihydroisoquinolin-2-ium streptomyces sp. gf3587 1.057 1.057 1 PMID:27547270 -1.5.1.48 3,4-dihydroisoquinoline streptomyces sp. gf3587 0.141 0.141 1 PMID:27547270 -1.5.1.48 6-(4-methoxyphenyl)-2,3,4,5-tetrahydropyridine streptomyces sp. gf3587 0.263 0.263 1 PMID:27547270 -1.5.1.48 6-(prop-1-en-2-yl)-2,3,4,5-tetrahydropyridine streptomyces sp. gf3587 2.35 2.35 1 PMID:27547270 -1.5.1.48 6-(thiophen-2-yl)-2,3,4,5-tetrahydropyridine streptomyces sp. gf3587 0.643 0.643 1 PMID:27547270 -1.5.1.48 6-cyclohexyl-2,3,4,5-tetrahydropyridine streptomyces sp. gf3587 0.0215 0.0215 1 PMID:27547270 -1.5.1.48 6-methyl-2,3,4,5-tetrahydropyridine streptomyces sp. gf3587 4.21 4.21 1 PMID:27547270 -1.5.1.48 6-phenyl-2,3,4,5-tetrahydropyridine streptomyces sp. gf3587 3.64 3.64 1 PMID:27547270 -1.5.1.48 6-propyl-2,3,4,5-tetrahydropyridine streptomyces sp. gf3587 4.63 4.63 1 PMID:27547270 -1.5.1.49 delta1-pyrroline-2-carboxylate colwellia psychrerythraea 124.5 67.425 2 PMID:24649405 -1.5.1.49 l-proline colwellia psychrerythraea 1.01 0.50845 2 PMID:24649405 -1.5.1.5 5,10-methenyltetrahydrofolate escherichia coli 19.9 19.9 1 PMID:25988590 -1.5.1.5 5,10-methylene tetrahydrofolate leishmania major 14.0 14.0 1 PMID:19183277 -1.5.1.5 5,10-methylene-tetrahydrofolate leishmania major 14.0 14.0 1 PMID:19183277 -1.5.1.5 5,10-methylenetetrahydrofolate homo sapiens 9.4 6.300000000000001 2 PMID:9454603 -1.5.1.5 5,10-methylenetetrahydropteroylglutamate homo sapiens 12.4 6.95 2 PMID:29225823 -1.5.1.5 5,10-methylenetetrahydropteroylpentaglutamate homo sapiens 15.4 10.9 2 PMID:29225823 -1.5.1.5 5,10-methylenetetrahydropteroylpoly-l-glutamate mus musculus 8.8 4.95 4 PMID:24733394 -1.5.1.5 nad+ mus musculus 3.6 3.6 1 PMID:24733394 -1.5.1.5 nad+ photobacterium phosphoreum 136.0 136.0 1 PMID:8765228 -1.5.1.5 nadp+ escherichia coli 17.08 17.08 1 PMID:25988590 -1.5.1.5 nadp+ homo sapiens 10.0 6.9 2 PMID:9454603 -1.5.1.5 nadp+ leishmania major 10.0 10.0 2 PMID:19183277 -1.5.1.5 nadp+ mus musculus 1.1 1.1 1 PMID:24733394 -1.5.1.5 nadp+ photobacterium phosphoreum 113.0 113.0 1 PMID:8765228 -1.5.1.50 7,8-dihydrobiopterin pseudomonas aeruginosa 0.8 0.8 1 PMID:32482721 -1.5.1.50 7,8-dihydromonapterin pseudomonas aeruginosa 1.9 1.9 1 PMID:32482721 -1.5.1.50 7,8-dihydroneopterin pseudomonas aeruginosa 0.7 0.7 1 PMID:32482721 -1.5.1.52 glyoxylate staphylococcus aureus 0.074 0.074 1 PMID:29618515 -1.5.1.52 nadph staphylococcus aureus 0.26 0.26 1 PMID:29618515 -1.5.1.52 oxaloacetate staphylococcus aureus 0.26 0.26 1 PMID:29618515 -1.5.1.52 pyruvate staphylococcus aureus 0.26 0.26 1 PMID:29618515 -1.5.1.53 5,10-methylenetetrahydrofolate homo sapiens 51.4 46.05 2 PMID:29891918 -1.5.1.53 nadph sus scrofa 26.7 26.7 1 PMID:6975779 -1.5.1.54 5,10-methylenetetrahydrofolate mycolicibacterium smegmatis 4.06 2.375 2 PMID:32253341 -1.5.1.54 menadione escherichia coli 3.2 3.2 1 PMID:11371182 -1.5.1.54 nadh escherichia coli 55.0 23.5 5 PMID:11371182;PMID:29407039;PMID:9922232 -1.5.1.54 nadh mycolicibacterium smegmatis 6.1 3.71 2 PMID:32253341 -1.5.1.55 1,3-diaminopropane synechocystis sp. pcc 6803 0.07 0.07 1 PMID:37878710 -1.5.1.55 agmatine synechocystis sp. pcc 6803 2.57 2.57 1 PMID:37878710 -1.5.1.55 nadph synechocystis sp. pcc 6803 2.57 2.57 1 PMID:37878710 -1.5.1.55 putrescine synechocystis sp. pcc 6803 0.32 0.32 1 PMID:37878710 -1.5.1.57 18-hydroxynorfluorocurarine strychnos nux-vomica 0.029 0.029 1 PMID:35794473 -1.5.1.57 norfluorocurarine strychnos nux-vomica 0.0056 0.0056 1 PMID:35794473 -1.5.1.6 10-formyltetrahydrofolate danio rerio 97.0 97.0 1 PMID:20381623 -1.5.1.6 10-formyltetrahydrofolate oryctolagus cuniculus 0.967 0.967 1 PMID:7929148 -1.5.1.6 10-formyltetrahydrofolate sus scrofa 1.0 1.0 1 PMID:3697368 -1.5.1.6 10-formyltetrahydropteroylpentaglutamate oryctolagus cuniculus 0.9 0.8835 2 PMID:8961940 -1.5.1.7 nadh saccharomyces cerevisiae 18.8 18.8 1 PMID:4287986 -1.5.3.1 2-isopropyl-4-(methylaminomethyl)thiazole thermomicrobium roseum 0.0458 0.0458 1 * -1.5.3.1 4-(ethylaminomethyl)pyridine thermomicrobium roseum 4e-05 4e-05 1 * -1.5.3.1 l-proline thermomicrobium roseum 0.0003 0.0003 1 * -1.5.3.1 n-ethylglycine corynebacterium sp. 2.2 2.2 1 PMID:7240129 -1.5.3.1 n-methyl-d-proline thermomicrobium roseum 0.0048 0.0048 1 * -1.5.3.1 n-methyl-dl-alanine paenarthrobacter ureafaciens 4.1 4.1 1 * -1.5.3.1 n-methyl-l-alanine corynebacterium sp. 3.4 3.4 1 PMID:7240129 -1.5.3.1 n-methyl-l-alanine thermomicrobium roseum 0.004 0.004 1 * -1.5.3.1 n-methyl-l-aspartate thermomicrobium roseum 0.0295 0.0295 1 * -1.5.3.1 n-methyl-l-leucine thermomicrobium roseum 0.0537 0.0537 1 * -1.5.3.1 n-methyl-l-phenylalanine thermomicrobium roseum 0.009 0.009 1 * -1.5.3.1 n-methyl-l-tryptophan thermomicrobium roseum 0.0045 0.0045 1 * -1.5.3.1 oxygen corynebacterium sp. u-96 18.9 18.9 1 PMID:17395614 -1.5.3.1 sarcosine bacillus sp. (in: firmicutes) 101.0 20.3 5 PMID:16977470;PMID:18251505;PMID:18693755 -1.5.3.1 sarcosine corynebacterium sp. 5.8 5.8 1 PMID:7240129 -1.5.3.1 sarcosine corynebacterium sp. u-96 18.5 18.5 1 PMID:17395614 -1.5.3.1 sarcosine paenarthrobacter ureafaciens 5.8 5.8 1 PMID:7240129 -1.5.3.1 sarcosine thermomicrobium roseum 0.053 0.0012000000000000001 10 * -1.5.3.10 n,n-dimethylglycine arthrobacter globiformis 14.3 10.6 3 PMID:11422368;PMID:12912903;PMID:16964976 -1.5.3.13 n-[(2r)-4-[(4-aminobutyl)amino]butan-2-yl]pyridine-4-carboxamide homo sapiens 0.0052 0.0052 1 PMID:30006473 -1.5.3.13 n-[(2s)-4-[(4-aminobutyl)amino]butan-2-yl]pyridine-4-carboxamide homo sapiens 1e-05 1e-05 1 PMID:30006473 -1.5.3.13 n1,n11-bis(ethyl)-norspermine mus musculus 0.415 0.415 1 PMID:12660232 -1.5.3.13 n1,n11-diacetylnorspermine homo sapiens 19.0 19.0 1 PMID:16354669 -1.5.3.13 n1,n12-bis(ethyl)-spermine mus musculus 1.93 1.93 1 PMID:12660232 -1.5.3.13 n1-acetylspermidine homo sapiens 15.0 8.5 3 PMID:15791459;PMID:16354669;PMID:30006473 -1.5.3.13 n1-acetylspermidine mus musculus 4.85 4.85 1 PMID:12660232 -1.5.3.13 n1-acetylspermine arabidopsis thaliana 0.084 0.05450000000000001 2 PMID:24906355 -1.5.3.13 n1-acetylspermine homo sapiens 31.7 24.35 2 PMID:15791459;PMID:16354669 -1.5.3.13 n1-acetylspermine mus musculus 27.0 15.765 2 PMID:12660232;PMID:28029774 -1.5.3.13 n1-benzoyl-(r)-alpha-methylspermidine homo sapiens 4.6 4.6 1 PMID:30006473 -1.5.3.13 n1-benzoyl-(s)-alpha-methylspermidine homo sapiens 0.03 0.03 1 PMID:30006473 -1.5.3.13 n1-phenyl-(r)-alpha-methylspermidine homo sapiens 0.00014 8.499999999999999e-05 2 PMID:30006473 -1.5.3.13 spermine homo sapiens 0.0004 0.0004 1 PMID:16354669 -1.5.3.13 spermine mus musculus 8.0 4.0875 2 PMID:12660232;PMID:28029774 -1.5.3.14 n1-acetylspermidine oryza sativa 9.8 8.2 2 PMID:24634478 -1.5.3.14 n1-acetylspermine oryza sativa 20.5 19.35 2 PMID:24634478 -1.5.3.14 norspermidine oryza sativa 2.3 1.7 2 PMID:24634478 -1.5.3.14 norspermine oryza sativa 9.0 8.65 2 PMID:24634478 -1.5.3.14 spermidine oryza sativa 287.9 157.2 2 PMID:24634478 -1.5.3.14 spermidine zea mays 55.1 50.2 3 PMID:16331971;PMID:21081665 -1.5.3.14 spermine oryza sativa 32.6 31.6 2 PMID:24634478 -1.5.3.14 spermine zea mays 39.3 32.9 3 PMID:16331971;PMID:21081665 -1.5.3.14 thermospermine oryza sativa 7.8 6.15 2 PMID:24634478 -1.5.3.16 n1-acetylspermidine saccharomyces cerevisiae 684.0 684.0 1 PMID:12670477 -1.5.3.16 n1-acetylspermine arabidopsis thaliana 0.2 0.2 3 PMID:16778015;PMID:21081665 -1.5.3.16 n1-acetylspermine homo sapiens 0.28 0.28 2 PMID:18422650 -1.5.3.16 n1-acetylspermine saccharomyces cerevisiae 47.0 47.0 1 PMID:12670477 -1.5.3.16 n8-acetylspermidine saccharomyces cerevisiae 22.4 22.4 1 PMID:12670477 -1.5.3.16 norspermine arabidopsis thaliana 6.9 0.45 3 PMID:16778015;PMID:21081665 -1.5.3.16 spermidine arabidopsis thaliana 0.1 0.1 1 PMID:21081665 -1.5.3.16 spermine arabidopsis thaliana 4.6 1.4 7 PMID:16778015;PMID:18703589;PMID:21081665;PMID:24906355 -1.5.3.16 spermine homo sapiens 7.55 6.6 4 PMID:18422650;PMID:20000632;PMID:23828398 -1.5.3.16 spermine mus musculus 4.8 4.5 9 PMID:12458219;PMID:14764092;PMID:15313165;PMID:20839014;PMID:21809080;PMID:23828398;PMID:27295021 -1.5.3.16 spermine saccharomyces cerevisiae 165.0 165.0 1 PMID:12670477 -1.5.3.16 thermospermine arabidopsis thaliana 0.1 0.060000000000000005 2 PMID:21081665 -1.5.3.17 (3r,3'r)-dimethylspermine saccharomyces cerevisiae 0.77 0.77 1 PMID:30006473 -1.5.3.17 (3s,3's)-dimethylspermine saccharomyces cerevisiae 1.85 1.85 1 PMID:30006473 -1.5.3.17 n,n'-dibenzyl-1,4-diaminobutane mus musculus 0.9 0.9 1 PMID:22959971 -1.5.3.17 n1-acetylspermidine arabidopsis thaliana 1.0 0.521 2 PMID:18583528 -1.5.3.17 n1-acetylspermine arabidopsis thaliana 2.0 0.05450000000000001 6 PMID:18583528;PMID:21081665;PMID:24906355 -1.5.3.17 n1-acetylspermine mus musculus 49.0 49.0 1 PMID:22959971 -1.5.3.17 n1-acetylspermine oryza sativa 0.022 0.022 1 PMID:24105034 -1.5.3.17 n1-acetylspermine saccharomyces cerevisiae 15.1 15.1 1 PMID:23034052 -1.5.3.17 norspermine arabidopsis thaliana 2.9 0.5930000000000001 4 PMID:21081665;PMID:24906355 -1.5.3.17 norspermine oryza sativa 0.036 0.026999999999999996 2 PMID:24105034 -1.5.3.17 spermidine arabidopsis thaliana 4.6 1.25 5 PMID:18583528;PMID:21081665;PMID:24906355 -1.5.3.17 spermidine synechocystis sp. pcc 6803 0.17 0.17 1 PMID:28869871 -1.5.3.17 spermine arabidopsis thaliana 4.2 0.188 6 PMID:18583528;PMID:21081665;PMID:24906355 -1.5.3.17 spermine mus musculus 4.7 4.7 1 PMID:22959971 -1.5.3.17 spermine oryza sativa 0.043 0.034 2 PMID:24105034 -1.5.3.17 spermine saccharomyces cerevisiae 39.0 35.05 2 PMID:23034052;PMID:30006473 -1.5.3.17 spermine synechocystis sp. pcc 6803 0.31 0.31 1 PMID:28869871 -1.5.3.17 thermospermine arabidopsis thaliana 0.5 0.2575 4 PMID:21081665;PMID:24906355 -1.5.3.17 thermospermine oryza sativa 0.051 0.051 1 PMID:24105034 -1.5.3.19 4-methylaminobutanoate paenarthrobacter nicotinovorans 800.0 800.0 1 PMID:15606755 -1.5.3.19 sarcosine paenarthrobacter nicotinovorans 4.0 4.0 1 PMID:15606755 -1.5.3.21 4-aminobutanoate paenarthrobacter nicotinovorans 878.0 878.0 1 PMID:16689938 -1.5.3.21 4-methylaminobutanoate paenarthrobacter nicotinovorans 1230.0 1230.0 1 PMID:16689938 -1.5.3.24 n-ethyl-glycine corynebacterium sp. u-96 2.2 2.2 1 PMID:7240129 -1.5.3.24 n-methyl-l-alanine corynebacterium sp. u-96 2.1 1.9500000000000002 2 PMID:7240129 -1.5.3.24 sarcosine corynebacterium sp. u-96 17.5 11.65 2 PMID:20675294;PMID:7240129 -1.5.3.25 deoxy-d-fructosyl-acgly-lys aspergillus fumigatus 1.4 1.4 1 PMID:17439148 -1.5.3.25 deoxy-d-fructosyl-acphe-lys aspergillus fumigatus 1.8 1.8 1 PMID:17439148 -1.5.3.25 deoxy-d-fructosyl-lys-phe aspergillus fumigatus 0.5 0.5 1 PMID:17439148 -1.5.3.25 deoxy-d-fructosyl-lys-ser aspergillus fumigatus 0.3 0.3 1 PMID:17439148 -1.5.3.25 epsilon-fructosyl-aminocaproate fusarium oxysporum f. sp. raphani 10.6 10.6 1 * -1.5.3.25 fructosyl adamantanamine aspergillus fumigatus 0.48 0.48 1 PMID:23354448 -1.5.3.25 fructosyl adamantanamine aspergillus sp. 2.25 1.525 2 PMID:9013588 -1.5.3.25 fructosyl glycine arthrobacter sp. 2-4-1 8.0 8.0 1 * -1.5.3.25 fructosyl glycine aspergillus sp. 3.2 1.9000000000000001 2 PMID:11914093 -1.5.3.25 fructosyl l-alanine fusarium oxysporum f. sp. raphani 21.0 21.0 1 * -1.5.3.25 fructosyl l-valine arthrobacter sp. 2-4-1 10.6 10.6 1 * -1.5.3.25 fructosyl l-valine fusarium oxysporum f. sp. raphani 16.1 13.5 2 * -1.5.3.25 fructosyl l-valine ulocladium sp. js-103 69.8 69.8 1 PMID:17046541 -1.5.3.25 fructosyl poly-l-lysine aspergillus fumigatus 0.008 0.008 1 PMID:23354448 -1.5.3.25 fructosyl propylamine aspergillus fumigatus 3.5 3.5 1 PMID:15629109 -1.5.3.25 fructosyl propylamine aspergillus sp. 5.8 2.7 3 PMID:10684633;PMID:11914093 -1.5.3.25 fructosyl-l-lysine aspergillus fumigatus 21.55 21.55 1 PMID:29445091 -1.5.3.25 gamma-fructosyl-aminobutanoate fusarium oxysporum f. sp. raphani 9.73 9.73 1 * -1.5.3.25 nepsilon-(1-deoxy-d-fructos-1-yl)-l-lysine aspergillus fumigatus 1.1 1.1 1 PMID:17439148 -1.5.3.25 nepsilon-fructosyl-nalpha-benzyloxycarbonyl-l-lysine fusarium oxysporum f. sp. raphani 16.0 15.75 2 * -1.5.3.25 nepsilon-fructosyl-nalpha-benzyloxycarbonyl-l-lysine ulocladium sp. js-103 27.5 27.5 1 PMID:17046541 -1.5.3.25 nepsilon-fructosyl-nalpha-t-butoxycarbonyl-l-lysine aspergillus sp. 5.5 4.85 2 PMID:9013588 -1.5.3.5 (s)-6-hydroxynicotine ochrobactrum sp. sjy1 25.8 25.8 1 PMID:25344232 -1.5.3.5 (s)-6-hydroxynicotine paenarthrobacter nicotinovorans 78.0 67.0 2 PMID:28080034;PMID:32750321 -1.5.3.5 (s)-6-hydroxynicotine shinella sp. 7.3 7.3 1 PMID:25002425 -1.5.3.5 (s)-6-hydroxynornicotine paenarthrobacter nicotinovorans 16.0 16.0 1 PMID:28080034 -1.5.3.5 (s)-nicotine paenarthrobacter nicotinovorans 0.1 0.1 1 PMID:32750321 -1.5.3.5 (s)-nicotine shinella sp. 2.03 2.03 1 PMID:25002425 -1.5.3.5 6-hydroxy-l-nicotine paenarthrobacter nicotinovorans 29.3 29.3 1 PMID:4405081;PMID:5646150 -1.5.3.6 (r)-6-hydroxynicotine paenarthrobacter nicotinovorans 77.0 77.0 1 PMID:31046245 -1.5.3.6 (r)-6-hydroxynornicotine paenarthrobacter nicotinovorans 8.1 8.1 1 PMID:31046245 -1.5.3.6 6-hydroxy-d-nicotine paenarthrobacter nicotinovorans 19.8 19.8 1 PMID:4405081 -1.5.5.1 6-(10-bromodecyl)ubiquinone sus scrofa 210.0 210.0 1 PMID:1991113 -1.5.5.1 6-(10-hydroxydecyl)ubiquinone sus scrofa 132.0 132.0 1 PMID:1991113 -1.5.5.1 6-bis(isoprenyl)ubiquinone homo sapiens 68.7 68.7 1 PMID:14640977 -1.5.5.1 6-heptylubiquinone sus scrofa 182.0 182.0 1 PMID:1991113 -1.5.5.1 6-isoprenylubiquinone homo sapiens 34.5 34.5 1 PMID:14640977 -1.5.5.1 6-nonylubiquinone sus scrofa 246.0 246.0 1 PMID:1991113 -1.5.5.1 bromodecylubiquinone homo sapiens 60.8 60.8 1 PMID:14640977 -1.5.5.1 decylubiquinone homo sapiens 74.3 67.1 2 PMID:12049629;PMID:14640977 -1.5.5.1 duroquinone homo sapiens 18.1 18.1 1 PMID:14640977 -1.5.5.1 electron-transferring flavoprotein homo sapiens 21.4 21.4 1 PMID:12049629 -1.5.5.1 electron-transferring flavoprotein sus scrofa 200.0 90.0 5 PMID:1991113;PMID:2996585;PMID:4052375 -1.5.5.1 heptylubiquinone homo sapiens 54.0 54.0 1 PMID:14640977 -1.5.5.1 hydroxydecylubiquinone homo sapiens 67.0 67.0 1 PMID:14640977 -1.5.5.1 menadione homo sapiens 6.6 6.6 1 PMID:14640977 -1.5.5.1 nonylubiquinone homo sapiens 61.3 61.3 1 PMID:14640977 -1.5.5.1 pentadecylubiquinone homo sapiens 7.4 7.4 1 PMID:14640977 -1.5.5.1 reduced electron-transferring flavoprotein cereibacter sphaeroides 8.0 8.0 1 PMID:18672901 -1.5.5.1 semiquinone electron-transferring flavoprotein homo sapiens 81.4 81.4 1 PMID:12049629 -1.5.5.1 tridecylubiquinone homo sapiens 31.5 31.5 1 PMID:14640977 -1.5.5.1 ubiqinone-2 homo sapiens 78.8 78.8 1 PMID:12049629 -1.5.5.1 ubiquinone-1 homo sapiens 33.5 33.5 1 PMID:12049629 -1.5.5.1 ubiquinone-1 sus scrofa 115.0 99.5 2 PMID:1991113;PMID:3053288;PMID:3593226 -1.5.5.1 ubiquinone-2 sus scrofa 162.0 162.0 1 PMID:1991113 -1.5.5.1 ubiquinone-4 homo sapiens 35.5 35.5 1 PMID:12049629 -1.5.5.2 l-proline escherichia coli 29.0 18.5 6 PMID:15449943;PMID:15450175;PMID:16156643;PMID:19140736;PMID:22148640;PMID:24352662 -1.5.5.2 l-proline mycobacterium tuberculosis 33.5 33.5 1 PMID:23834473 -1.5.5.2 l-proline thermus thermophilus 9.8 7.9 3 PMID:28256579 -1.5.5.2 trans-4-hydroxy-l-proline escherichia coli 2.5 2.5 1 PMID:19140736 -1.5.5.3 coenzyme q1 homo sapiens 0.19 0.19 1 PMID:25697095 -1.5.5.3 duroquinone homo sapiens 0.27 0.27 1 PMID:25697095 -1.5.5.3 menaquinone homo sapiens 0.28 0.28 1 PMID:25697095 -1.5.5.3 trans-4-hydroxy-l-proline homo sapiens 0.19 0.19 1 PMID:25697095 -1.5.7.3 n,n-dimethylglycine chromohalobacter israelensis 0.31 0.31 1 PMID:32631860 -1.5.7.3 sarcosine chromohalobacter israelensis 0.28 0.28 1 PMID:32631860 -1.5.8.2 alphar237k mutant electron transferring flavoprotein methylophilus methylotrophus 1.46 1.46 1 PMID:18407658 -1.5.8.2 electron transferring flavoprotein methylophilus methylotrophus 9.67 9.67 1 PMID:18407658 -1.5.8.2 trimethylamine methylophilus methylotrophus 40.0 16.65 6 PMID:10924112;PMID:8188674;PMID:8993316;PMID:9725623 -1.5.8.3 sarcosine rattus norvegicus 0.065 0.065 1 PMID:2417560 -1.5.8.4 ferrocene homo sapiens 3.55 3.55 1 PMID:27486859 -1.5.8.4 n,n-dimethylglycine chromohalobacter israelensis 0.32 0.32 1 PMID:32631860 -1.5.8.4 n,n-dimethylglycine homo sapiens 3.55 0.7315 6 PMID:18937046;PMID:27486859 -1.5.8.4 n,n-dimethylglycine rattus norvegicus 0.14 0.14 1 PMID:2417560 -1.5.8.4 oxidized 2,6-dichlorophenolindophenol homo sapiens 0.73 0.73 1 PMID:27486859 -1.5.8.4 sarcosine chromohalobacter israelensis 0.28 0.28 1 PMID:32631860 -1.5.98.2 n5,n10-methylenetetrahydromethanopterin methanopyrus kandleri 275.0 275.0 1 PMID:1953299 -1.5.98.2 reduced coenzyme f420 methanopyrus kandleri 275.0 275.0 1 PMID:1953299 -1.5.98.3 reduced coenzyme f420 methanolobus tindarius 25.5 25.5 1 PMID:1735436 -1.5.99.12 1,4-naphthoquinone zea mays 169.6 169.6 1 PMID:14965342 -1.5.99.12 2,3-dimethoxy-5-methyl-1,4-benzoquinone zea mays 143.6 143.6 1 PMID:14965342 -1.5.99.12 2,6-dichlorophenolindophenol zea mays 278.0 228.2 2 PMID:14965342 -1.5.99.12 caffeic acid zea mays 0.3 0.3 1 PMID:14965342 -1.5.99.12 coenzyme q1 zea mays 123.1 123.1 1 PMID:14965342 -1.5.99.12 cytochrome c zea mays 0.8 0.8 1 PMID:14965342 -1.5.99.12 daphnoretin zea mays 1.0 1.0 1 PMID:14965342 -1.5.99.12 kinetin zea mays 1.9 1.9 1 PMID:16686601 -1.5.99.12 n-methyl-isopentenyladenine zea mays 0.13 0.13 1 PMID:16686601 -1.5.99.12 n6-(2-isopentenyl)adenine arabidopsis thaliana 5.4 5.4 1 * -1.5.99.12 n6-(2-isopentenyl)adenine zea mays 143.6 91.8 2 PMID:14965342;PMID:16686601 -1.5.99.12 n6-(2-isopentenyl)adenosine zea mays 129.8 129.8 1 PMID:14965342 -1.5.99.12 n6-isopentenyladenine zea mays 128.0 128.0 1 PMID:15927342 -1.5.99.12 n6-isopentenyladenosine zea mays 62.0 62.0 1 PMID:15927342 -1.5.99.12 o-coumaric acid zea mays 0.3 0.3 1 PMID:14965342 -1.5.99.12 o2 zea mays 0.6 0.35 2 PMID:14965342 -1.5.99.12 p-topolin zea mays 0.23 0.23 1 PMID:16686601 -1.5.99.12 rosmarinic acid zea mays 0.4 0.4 1 PMID:14965342 -1.5.99.12 scopoletin zea mays 1.4 1.4 1 PMID:14965342 -1.5.99.12 spinach plantacyanine zea mays 0.9 0.9 1 PMID:14965342 -1.5.99.12 vitamin k1 zea mays 2.3 2.3 1 PMID:14965342 -1.5.99.12 vitamin k3 zea mays 85.4 85.4 1 PMID:14965342 -1.5.99.12 zeatin zea mays 135.0 135.0 1 PMID:15927342 -1.5.99.12 zeatin riboside zea mays 21.0 21.0 1 PMID:15927342 -1.5.99.14 1-(6-hydroxypyridin-3-yl)-4-(methylamino)butan-1-one paenarthrobacter nicotinovorans 10.58 9.059999999999999 8 PMID:34299660 -1.5.99.16 (2-aminoethyl)phosphonate azospirillum sp. b510 2.2 2.2 1 PMID:37876809 -1.5.99.16 2-(methylaminoethyl)phosphonate azospirillum sp. b510 9.0 9.0 1 PMID:37876809 -1.5.99.4 (s)-nicotine oryctolagus cuniculus 0.597 0.5325 2 PMID:2302249 -1.5.99.5 n-methyl-l-glutamate aminobacter aminovorans 0.7 0.7 1 PMID:597255 -1.6.1.1 nadh acidobacteriota bacterium 10.1 10.1 1 * -1.6.1.1 nadh nocardia jiangxiensis 44.5 44.5 1 * -1.6.1.1 nadh streptomyces avermitilis 117.5 117.5 1 PMID:34931264 -1.6.1.1 nadph acidobacteriota bacterium 10.7 10.7 1 * -1.6.1.1 nadph escherichia coli 167.9 167.9 2 PMID:21545646 -1.6.1.1 nadph nocardia jiangxiensis 50.7 50.7 1 * -1.6.1.1 nadph pseudomonas aeruginosa 333.0 333.0 1 PMID:4393131 -1.6.1.1 nadph streptomyces avermitilis 201.5 201.5 1 PMID:34931264 -1.6.1.1 thio-nad+ acidobacteriota bacterium 8.9 8.1 2 * -1.6.1.1 thio-nad+ escherichia coli 259.5 259.5 2 PMID:21545646 -1.6.1.1 thio-nad+ nocardia jiangxiensis 74.5 61.3 2 * -1.6.1.1 thio-nad+ streptomyces avermitilis 317.4 291.95 2 PMID:34931264 -1.6.2.2 1,4-naphthoquinone homo sapiens 0.163 0.163 1 PMID:30222979 -1.6.2.2 2,6-dichlorophenolindophenol musca domestica 50.2 50.2 1 PMID:8936052 -1.6.2.2 2-hydroxyestradiol homo sapiens 0.003 0.003 1 PMID:30222979 -1.6.2.2 2-methyl-1,4-naphthoquinone homo sapiens 0.058 0.058 1 PMID:30222979 -1.6.2.2 9,10-phenanthrenequinone homo sapiens 0.097 0.097 1 PMID:30222979 -1.6.2.2 ferricyanide canis lupus familiaris 767.0 767.0 1 PMID:16814740 -1.6.2.2 ferricyanide homo sapiens 827.0 688.5 6 PMID:16310381;PMID:2992639;PMID:6841358 -1.6.2.2 ferricyanide lathyrus oleraceus 367.0 367.0 1 PMID:16665720 -1.6.2.2 ferricyanide musca domestica 307.0 307.0 1 PMID:8936052 -1.6.2.2 ferricyanide oryctolagus cuniculus 667.0 667.0 1 PMID:672620 -1.6.2.2 ferricyanide rattus norvegicus 800.0 800.0 6 PMID:11695905;PMID:11913972;PMID:14609324;PMID:15488472;PMID:15709757;PMID:16216070 -1.6.2.2 ferricyanide sus scrofa 822.0 720.0 4 PMID:10082957;PMID:12459552;PMID:19716516 -1.6.2.2 ferricytochome b5 rattus norvegicus 417.0 417.0 1 PMID:15488472 -1.6.2.2 ferricytochrome b5 homo sapiens 872.0 480.0 4 PMID:16310381;PMID:16469290;PMID:672649;PMID:8482363 -1.6.2.2 ferricytochrome b5 rattus norvegicus 400.0 318.5 4 PMID:11695905;PMID:11913972;PMID:14609324;PMID:15709757 -1.6.2.2 ferricytochrome b5 sus scrofa 911.0 560.0 5 PMID:10082957;PMID:11574067;PMID:12459552;PMID:19716516 -1.6.2.2 ferrocytochrome b5 canis lupus familiaris 600.0 600.0 1 PMID:16814740 -1.6.2.2 ferrocytochrome b5 rattus norvegicus 400.0 400.0 1 PMID:16216070 -1.6.2.2 nadh bos taurus 500.0 500.0 1 * -1.6.2.2 nadh homo sapiens 754.0 377.3665 2 PMID:15953014;PMID:16469290 -1.6.2.2 nadh musca domestica 332.0 332.0 1 PMID:8936052 -1.6.2.2 nadh rattus norvegicus 800.0 800.0 1 PMID:14503867 -1.6.2.2 nadh sus scrofa 1100.0 742.0 6 PMID:10082957;PMID:11574067;PMID:12459552;PMID:19716516 -1.6.2.2 nadph homo sapiens 33.0 33.0 1 PMID:15953014;PMID:16216070 -1.6.2.2 nadph musca domestica 297.0 297.0 1 PMID:8936052 -1.6.2.2 nadph rattus norvegicus 33.0 33.0 2 PMID:14503867;PMID:15953014;PMID:16216070 -1.6.2.2 nitrofurantoin homo sapiens 0.017 0.017 1 PMID:30222979 -1.6.2.2 o2 homo sapiens 1.37 1.27 2 PMID:29227865 -1.6.2.4 5-cyano-2,3-ditolyl tetrazolium chloride rattus norvegicus 42.0 42.0 1 PMID:18941714 -1.6.2.4 cytochrome c rattus norvegicus 50.0 22.2 4 PMID:19661994;PMID:234249;PMID:9774150 -1.6.2.4 cytochrome c starmerella apicola 31.92 31.92 1 PMID:22526787 -1.6.2.4 ferricyanide andrographis paniculata 9.85 6.21 2 PMID:28410952 -1.6.2.4 ferricyanide arabidopsis thaliana 146.0 146.0 1 PMID:26361974 -1.6.2.4 ferricyanide artemisia annua 169.0 169.0 1 PMID:26361974 -1.6.2.4 ferricyanide capsicum annuum 80.0 80.0 1 PMID:24935229 -1.6.2.4 ferricyanide homo sapiens 43.5 34.95 2 PMID:24589657;PMID:26361974 -1.6.2.4 ferricyanide trypanosoma cruzi 64.5 64.5 1 PMID:3923933 -1.6.2.4 ferricytochrome c andrographis paniculata 5.58 3.4050000000000002 2 PMID:28410952 -1.6.2.4 ferricytochrome c arabidopsis thaliana 3.7 3.7 1 PMID:26361974 -1.6.2.4 ferricytochrome c artemisia annua 51.4 51.4 1 PMID:26361974 -1.6.2.4 ferricytochrome c botryococcus braunii 2.78 2.78 1 PMID:28818427 -1.6.2.4 ferricytochrome c candida tropicalis 102.0 102.0 1 PMID:107026 -1.6.2.4 ferricytochrome c capsicum annuum 45.7 45.7 1 PMID:24935229 -1.6.2.4 ferricytochrome c gossypium hirsutum 10.1 7.035 2 PMID:19883924 -1.6.2.4 ferricytochrome c homo sapiens 20.0 13.235 2 PMID:17635179;PMID:26361974 -1.6.2.4 ferricytochrome c phanerodontia chrysosporium 42.0 30.5 2 PMID:12437968 -1.6.2.4 ferricytochrome c priestia megaterium 417.0 53.3 3 PMID:27238232;PMID:8942669 -1.6.2.4 ferricytochrome c rattus norvegicus 35.0 20.0 5 PMID:20152939 -1.6.2.4 ferricytochrome c sus scrofa 22.5 21.5 2 PMID:234249;PMID:4374137 -1.6.2.4 ferricytochrome c trypanosoma cruzi 15.0 15.0 1 PMID:3923933 -1.6.2.4 menadione trypanosoma cruzi 1.45 1.45 1 PMID:3923933 -1.6.2.4 nadh artemisia annua 16.5 16.5 1 PMID:24299267 -1.6.2.4 nadph andrographis paniculata 2.48 1.7850000000000001 2 PMID:28410952 -1.6.2.4 nadph artemisia annua 65.9 65.9 1 PMID:24299267 -1.6.2.4 nadph botryococcus braunii 3.66 3.66 1 PMID:28818427 -1.6.2.4 nadph gossypium hirsutum 10.2 7.029999999999999 2 PMID:19883924 -1.6.2.4 nadph homo sapiens 20.0 20.0 3 PMID:17635179;PMID:24589657;PMID:27461959 -1.6.2.4 oxidized 2,6-dichlorophenolindophenol trypanosoma cruzi 7.63 7.63 1 PMID:3923933 -1.6.2.4 oxidized 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide capsicum annuum 15.7 15.7 1 PMID:24935229 -1.6.2.4 oxidized 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide rattus norvegicus 28.3 11.67 5 PMID:20152939 -1.6.2.6 ferrileghemoglobin glycine max 6.2 6.2 3 PMID:11788775;PMID:12232320 -1.6.2.6 ferrileghemoglobin vigna unguiculata 3.1 2.8 2 PMID:10729615 -1.6.2.6 lipoamide glycine max 392.0 211.5 2 PMID:11788775;PMID:12232320 -1.6.2.6 nadh glycine max 137.0 137.0 1 PMID:11788775 -1.6.3.1 nadh saccharolobus solfataricus 4.4 4.4 1 PMID:10625624 -1.6.3.1 nadph helicobacter pylori 2.8 2.8 1 PMID:19438716 -1.6.3.2 nadh thermococcus kodakarensis 68.0 68.0 1 PMID:23453203 -1.6.3.2 nadh thermococcus profundus 6.2 6.2 1 PMID:18959761 -1.6.3.2 nadph thermococcus profundus 2.5 2.5 1 PMID:18959761 -1.6.3.3 beta-nadh pyrococcus horikoshii 115.0 115.0 1 * -1.6.3.4 bnah lactiplantibacillus pentosus 0.17 0.17 1 PMID:26441891 -1.6.3.4 mnah lactiplantibacillus pentosus 0.14 0.14 1 PMID:26441891 -1.6.3.4 nadh lactiplantibacillus pentosus 43.4 43.4 1 PMID:26441891 -1.6.3.4 nadh streptococcus pyogenes 286.7 286.7 1 PMID:24687749 -1.6.5.10 1,2-naphthoquinone homo sapiens 0.21 0.21 1 PMID:19000905 -1.6.5.10 1,2-naphthoquinone saccharomyces cerevisiae 4.2 4.2 1 PMID:21276778 -1.6.5.10 1,4-benzoquinone homo sapiens 0.207 0.207 1 PMID:19000905 -1.6.5.10 1,4-benzoquinone kluyveromyces marxianus 15833.0 15833.0 1 PMID:14536026 -1.6.5.10 1,4-benzoquinone pseudomonas aeruginosa 5.9 5.9 1 PMID:29715013 -1.6.5.10 1,4-naphthoquinone homo sapiens 0.195 0.195 1 PMID:19000905 -1.6.5.10 2,3-dichloro-5,6-dicyano-1,4-benzoquinone kluyveromyces marxianus 520.0 520.0 1 PMID:14536026 -1.6.5.10 2,3-dimethoxy-5-methyl-1,4-benzoquinone homo sapiens 0.068 0.068 1 PMID:19000905 -1.6.5.10 2,5-dimethyl-4-benzoquinone synechocystis sp. 36.7 36.7 1 PMID:22304305 -1.6.5.10 2,6-dimethoxy-1,4-benzoquinone pseudomonas aeruginosa 5.5 5.5 1 PMID:29715013 -1.6.5.10 2-hydroxy-1,4-naphthoquinone synechocystis sp. 11.0 11.0 1 PMID:22304305 -1.6.5.10 5-hydroxy-1,4-naphthoquinone homo sapiens 0.19 0.19 1 PMID:19000905 -1.6.5.10 9,10-phenanthrenequinone homo sapiens 0.305 0.305 1 PMID:19000905 -1.6.5.10 9,10-phenanthrenequinone rattus norvegicus 2.85 2.85 1 PMID:9692994 -1.6.5.10 9,10-phenanthrenequinone saccharomyces cerevisiae 4.2 4.2 1 PMID:21276778 -1.6.5.10 anthraquinone-2-sulfonate synechocystis sp. 9.4 9.4 1 PMID:22304305 -1.6.5.10 coenzyme q10 synechocystis sp. 5.0 5.0 1 PMID:22304305 -1.6.5.10 dibromothymoquinone synechocystis sp. 35.0 35.0 1 PMID:22304305 -1.6.5.10 duroquinone bacillus subtilis 2.67 2.67 1 PMID:15890652 -1.6.5.10 duroquinone synechocystis sp. 25.0 25.0 1 PMID:22304305 -1.6.5.10 hydroquinone kluyveromyces marxianus 1600.0 1600.0 1 PMID:14536026 -1.6.5.10 menadione bacillus subtilis 3.04 3.04 1 PMID:15890652 -1.6.5.10 menadione homo sapiens 0.212 0.212 1 PMID:19000905 -1.6.5.10 menadione synechocystis sp. 26.0 26.0 1 PMID:22304305 -1.6.5.10 nadph pseudomonas aeruginosa 10.1 10.1 1 PMID:29715013 -1.6.5.10 nadph xanthomonas citri 884.0 884.0 1 PMID:31911239 -1.6.5.10 phenyl-1,4-benzoquinone kluyveromyces marxianus 360.0 360.0 1 PMID:14536026 -1.6.5.12 menadione arabidopsis thaliana 0.44 0.44 1 PMID:26023160 -1.6.5.12 menadione synechocystis sp. 3.2 3.2 1 PMID:26023160 -1.6.5.2 1,4-benzoquinone archaeoglobus fulgidus 3200.0 3200.0 1 PMID:16672604 -1.6.5.2 1,4-benzoquinone escherichia coli 370.0 370.0 1 PMID:16672604 -1.6.5.2 1,4-benzoquinone rattus norvegicus 769.0 769.0 1 PMID:12147263 -1.6.5.2 1,4-naphthoquinone rattus norvegicus 431.0 431.0 2 PMID:12147263;PMID:12859987 -1.6.5.2 1,8-dihydroxy-9,10-anthraquinone rattus norvegicus 0.5 0.5 1 PMID:12859987 -1.6.5.2 2,3-diglutathionyl-1,4-naphthoquinone rattus norvegicus 4.4 4.4 1 PMID:12147263 -1.6.5.2 2,5-bis(ethylamine)-3,6-diaziridinyl-1,4-benzoquinone rattus norvegicus 40.0 40.0 1 PMID:12859987 -1.6.5.2 2,5-di-tert-butyl-1,4-benzoquinone phanerodontia chrysosporium 1400.0 1400.0 1 PMID:16535104 -1.6.5.2 2,5-diaziridinyl-1,4-benzoquinone rattus norvegicus 2331.0 1940.5 2 PMID:12147263;PMID:12859987 -1.6.5.2 2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone rattus norvegicus 2000.0 2000.0 1 PMID:12859987 -1.6.5.2 2,5-dimethyl-1,4-benzoquinone rattus norvegicus 500.0 500.0 1 PMID:12147263 -1.6.5.2 2,5-dimethyl-1,4-naphthoquinone rattus norvegicus 500.0 500.0 1 PMID:12859987 -1.6.5.2 2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinone rattus norvegicus 222.0 166.5 2 PMID:12147263;PMID:12859987 -1.6.5.2 2,6-dichlorophenolindophenol phanerodontia chrysosporium 330.0 330.0 1 PMID:16535104 -1.6.5.2 2,6-dimethoxy-1,4-benzoquinone phanerodontia chrysosporium 560.0 560.0 1 PMID:16535104 -1.6.5.2 2,6-dimethyl-1,4-benzoquinone rattus norvegicus 625.0 625.0 1 PMID:12147263 -1.6.5.2 2-hydroxy-1,4-naphthoquinone rattus norvegicus 232.0 232.0 1 PMID:12859987 -1.6.5.2 2-methoxy-1,4-benzoquinone phanerodontia chrysosporium 440000.0 440000.0 1 PMID:16535104 -1.6.5.2 2-methyl-1,4-benzoquinone rattus norvegicus 287.0 287.0 2 PMID:12147263;PMID:12859987 -1.6.5.2 2-methyl-1,4-naphthoquinone rattus norvegicus 380.0 380.0 2 PMID:12147263;PMID:12859987 -1.6.5.2 2-methyl-3-glutathionyl-5-hydroxy-1,4-naphthoquinone rattus norvegicus 26.3 26.3 1 PMID:12147263 -1.6.5.2 2-methyl-5-aziridinyl-1,4-benzoquinone rattus norvegicus 1540.0 1540.0 1 PMID:12859987 -1.6.5.2 2-methyl-5-hydroxy-1,4-naphthoquinone rattus norvegicus 500.0 500.0 2 PMID:12147263;PMID:12859987 -1.6.5.2 5,8-dihydroxy-1,4-naphthoquinone rattus norvegicus 71.0 71.0 2 PMID:12147263;PMID:12859987 -1.6.5.2 5-(aziridin-1-yl)-2,4-dinitrobenzamide homo sapiens 6.0 3.005 2 PMID:9367528 -1.6.5.2 5-hydroxy-1,4-naphthoquinone rattus norvegicus 242.0 242.0 2 PMID:12147263;PMID:12859987 -1.6.5.2 9,10-anthraquinone-2,6-disulfonate rattus norvegicus 2.3 2.3 1 PMID:12147263 -1.6.5.2 9,10-phenanthrene quinone rattus norvegicus 52.0 52.0 2 PMID:12147263;PMID:12859987 -1.6.5.2 benzoquinone pseudomonas putida 930.0 930.0 1 PMID:15840577 -1.6.5.2 chromate(iv) pseudomonas putida 5.8 5.8 1 PMID:15840577 -1.6.5.2 chromate(vi) rattus norvegicus 1.8 1.8 1 PMID:17294702 -1.6.5.2 coenzyme q1 pseudomonas putida 6.4 6.4 1 PMID:15840577 -1.6.5.2 duroquinone pseudomonas putida 25.0 25.0 1 PMID:15840577 -1.6.5.2 menadione bos taurus 11700.0 11700.0 1 * -1.6.5.2 menadione cupriavidus pinatubonensis jmp134 350.7 350.7 1 PMID:18165297 -1.6.5.2 menadione giardia duodenalis 34.8 28.95 2 PMID:11238963 -1.6.5.2 menadione homo sapiens 1830.0 550.0 3 PMID:28236663;PMID:9367528 -1.6.5.2 menadione phanerodontia chrysosporium 4900.0 4900.0 1 PMID:16535104 -1.6.5.2 menadione pseudomonas putida 440.0 440.0 1 PMID:15840577 -1.6.5.2 menadione rattus norvegicus 0.11 0.11 1 PMID:17294702 -1.6.5.2 methyl red homo sapiens 3.83 2.0815 2 PMID:9367528 -1.6.5.2 nadh archaeoglobus fulgidus 120.0 120.0 1 PMID:16672604 -1.6.5.2 nadh escherichia coli 8.9 8.9 1 PMID:16672604 -1.6.5.2 nadh giardia duodenalis 62.7 47.2 2 PMID:11238963 -1.6.5.2 nadh homo sapiens 1590.0 1590.0 1 PMID:28236663 -1.6.5.2 nadh paracoccus denitrificans 258.0 258.0 1 PMID:24817153 -1.6.5.2 nadh phanerodontia chrysosporium 800.0 800.0 1 PMID:16535104 -1.6.5.2 nadh rattus norvegicus 192.0 192.0 1 PMID:1906347 -1.6.5.2 nadph archaeoglobus fulgidus 170.0 170.0 1 PMID:16672604 -1.6.5.2 nadph escherichia coli 34.2 20.1 2 PMID:16672604;PMID:18455185 -1.6.5.2 nadph giardia duodenalis 52.7 50.1 2 PMID:11238963 -1.6.5.2 nadph phanerodontia chrysosporium 760.0 760.0 1 PMID:16535104 -1.6.5.2 naphthoquinone giardia duodenalis 39.3 34.599999999999994 2 PMID:11238963 -1.6.5.2 oxidized 2,6-dichlorophenolindophenol homo sapiens 600.0 323.35 2 PMID:9367528 -1.6.5.2 oxidized 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium homo sapiens 11.0 11.0 1 PMID:9367528 -1.6.5.2 reduced dihydronicotinamide riboside homo sapiens 517.0 280.15 2 PMID:9367528 -1.6.5.2 reduced nicotinamide 2-azidoadenine dinucleotide rattus norvegicus 167.0 167.0 1 PMID:1906347 -1.6.5.2 reduced nicotinamide 8-azidoadenine dinucleotide rattus norvegicus 91.0 91.0 1 PMID:1906347 -1.6.5.2 tetramethyl-1,4-benzoquinone rattus norvegicus 1000.0 1000.0 1 PMID:12859987 -1.6.5.4 nadh cucumis sativus 200.0 200.0 1 PMID:4055727 -1.6.5.4 nadh physcomitrium patens 170.0 128.0 3 PMID:16983536 -1.6.5.4 nadh solanum lycopersicum 126.6 124.0 2 PMID:20085781 -1.6.5.4 nadph cucumis sativus 150.0 150.0 1 PMID:4055727 -1.6.5.5 1,2-naphthoquinone arabidopsis thaliana 54.0 54.0 1 PMID:10848984 -1.6.5.5 1,2-naphthoquinone cavia porcellus 39.0 39.0 1 PMID:10848984 -1.6.5.5 1,2-naphthoquinone homo sapiens 2.8 2.8 1 PMID:17497241 -1.6.5.5 1,2-naphthoquinone saccharomyces cerevisiae 4.17 4.17 1 PMID:17497241 -1.6.5.5 1,4-benzoquinone arabidopsis thaliana 12.0 12.0 1 PMID:10848984 -1.6.5.5 1,4-benzoquinone cavia porcellus 5.9 4.65 2 PMID:10848984;PMID:1370456 -1.6.5.5 1,4-benzoquinone escherichia coli 62.0 62.0 1 PMID:27986535 -1.6.5.5 1,4-benzoquinone pseudomonas aeruginosa 90.0 88.5 2 PMID:31075192 -1.6.5.5 1,4-dihydroxy-9,10-anthraquinone escherichia coli 0.7 0.7 1 PMID:27986535 -1.6.5.5 1,4-naphthoquinone arabidopsis thaliana 3.0 3.0 1 PMID:10848984 -1.6.5.5 1,4-naphthoquinone cavia porcellus 1.0 1.0 1 PMID:10848984 -1.6.5.5 1,4-naphthoquinone escherichia coli 46.0 46.0 1 PMID:27986535 -1.6.5.5 1,4-naphthoquinone pseudomonas aeruginosa 80.0 80.0 1 PMID:31075192 -1.6.5.5 1,8-dihydroxy-9,10-anthraquinone escherichia coli 1.6 1.6 1 PMID:27986535 -1.6.5.5 2,3,5,6-tetramethyl-1,4-benzoquinone pseudomonas aeruginosa 15.0 15.0 1 PMID:31075192 -1.6.5.5 2,3-dichloro-1,4-naphthoquinone escherichia coli 61.0 61.0 1 PMID:27986535 -1.6.5.5 2,3-dimethoxy-5-methyl-1,4-benzoquinone pseudomonas aeruginosa 66.0 66.0 1 PMID:31075192 -1.6.5.5 2,5-dimethyl-4-benzoquinone synechocystis sp. 36.7 36.7 1 PMID:22304305 -1.6.5.5 2,6-dimethoxy-1,4-benzoquinone pseudomonas aeruginosa 41.0 41.0 1 PMID:31075192 -1.6.5.5 2,6-dimethyl-1,4-benzoquinone escherichia coli 51.0 51.0 1 PMID:27986535 -1.6.5.5 2-hexenal homo sapiens 0.28 0.28 1 PMID:20835842 -1.6.5.5 2-hydroxy-1,4-naphthoquinone escherichia coli 72.0 72.0 1 PMID:27986535 -1.6.5.5 2-hydroxy-1,4-naphthoquinone synechocystis sp. 11.0 11.0 1 PMID:22304305 -1.6.5.5 2-hydroxy-3-methyl-1,4-naphthoquinone escherichia coli 56.0 56.0 1 PMID:27986535 -1.6.5.5 2-methyl-1,4-benzoquinone escherichia coli 54.0 54.0 1 PMID:27986535 -1.6.5.5 2-methyl-1,4-naphthoquinone escherichia coli 6.0 6.0 1 PMID:27986535 -1.6.5.5 2-methyl-1,4-naphthoquinone pseudomonas aeruginosa 63.0 63.0 1 PMID:31075192 -1.6.5.5 2-nonenal homo sapiens 0.11 0.11 1 PMID:20835842 -1.6.5.5 2-pentenal homo sapiens 0.2 0.2 1 PMID:20835842 -1.6.5.5 3-buten-2-one homo sapiens 0.16 0.16 1 PMID:20835842 -1.6.5.5 3-nonen-2-one homo sapiens 0.21 0.21 1 PMID:20835842 -1.6.5.5 3-penten-2-one homo sapiens 0.2 0.2 1 PMID:20835842 -1.6.5.5 4-hydroxy-2-hexenal homo sapiens 1.33 1.33 1 PMID:20835842 -1.6.5.5 4-hydroxy-2-nonenal homo sapiens 1.15 1.15 1 PMID:20835842 -1.6.5.5 5,8-dihydroxy-1,4-naphthoquinone escherichia coli 12.0 12.0 1 PMID:27986535 -1.6.5.5 5-hydroxy-1,4-naphthoquinone arabidopsis thaliana 1.9 1.9 1 PMID:10848984 -1.6.5.5 5-hydroxy-1,4-naphthoquinone cavia porcellus 4.9 3.75 2 PMID:10848984;PMID:1370456 -1.6.5.5 5-hydroxy-1,4-naphthoquinone escherichia coli 22.0 22.0 1 PMID:27986535 -1.6.5.5 5-hydroxy-1,4-naphthoquinone pseudomonas aeruginosa 82.0 82.0 1 PMID:31075192 -1.6.5.5 5-hydroxy-2-methyl-1,4-naphthoquinone cavia porcellus 0.37 0.37 1 PMID:10848984 -1.6.5.5 5-hydroxy-2-methyl-1,4-naphtoquinone arabidopsis thaliana 3.8 3.8 1 PMID:10848984 -1.6.5.5 9,10-anthraquinone-2-sulfonic acid escherichia coli 1.4 1.4 1 PMID:27986535 -1.6.5.5 9,10-phenanthrenequinone arabidopsis thaliana 98.0 98.0 1 PMID:10848984 -1.6.5.5 9,10-phenanthrenequinone cavia porcellus 19.0 14.5 2 PMID:10848984;PMID:1370456 -1.6.5.5 9,10-phenanthrenequinone escherichia coli 54.0 54.0 1 PMID:27986535 -1.6.5.5 9,10-phenanthrenequinone homo sapiens 2.2 1.665 2 PMID:17497241;PMID:33483563 -1.6.5.5 9,10-phenanthrenequinone saccharomyces cerevisiae 4.17 4.17 1 PMID:17497241 -1.6.5.5 anthraquinone-2-sulfonate synechocystis sp. 9.4 9.4 1 PMID:22304305 -1.6.5.5 coenzyme q10 synechocystis sp. 5.0 5.0 1 PMID:22304305 -1.6.5.5 decyl-plastoquinone arabidopsis thaliana 0.1 0.1 1 PMID:10848984 -1.6.5.5 dibromothymoquinone synechocystis sp. 35.0 35.0 1 PMID:22304305 -1.6.5.5 dichlorophenolindophenol arabidopsis thaliana 7.5 7.5 1 PMID:10848984 -1.6.5.5 dichlorophenolindophenol cavia porcellus 1.5 1.5 1 PMID:10848984 -1.6.5.5 duroquinone synechocystis sp. 25.0 25.0 1 PMID:22304305 -1.6.5.5 ferricytochrome arabidopsis thaliana 0.03 0.03 1 PMID:10848984 -1.6.5.5 menadione synechocystis sp. 26.0 26.0 1 PMID:22304305 -1.6.5.5 nadh pseudomonas aeruginosa 13.0 12.0 3 PMID:31075192 -1.6.5.5 nadph pseudomonas aeruginosa 16.0 15.0 3 PMID:31075192 -1.6.5.5 propenal homo sapiens 1.66 1.66 1 PMID:20835842 -1.6.5.5 riboflavin escherichia coli 4.2 4.2 1 PMID:27986535 -1.6.5.5 tetramethyl-1,4-benzoquinone escherichia coli 2.5 2.5 1 PMID:27986535 -1.6.5.9 nadh saccharomyces cerevisiae 0.031 0.031 1 PMID:3138118 -1.6.99.1 2,4,6-trinitrotoluene bacillus subtilis 3.19 3.19 3 PMID:12660247;PMID:15249051 -1.6.99.1 2-cyclohexen-1-one shewanella oneidensis 4.75 4.75 1 PMID:16293111 -1.6.99.1 acrolein shewanella oneidensis 11.66 6.035 2 PMID:16293111 -1.6.99.1 cyclohex-2-enone bacillus subtilis 4.38 4.38 3 PMID:12660247;PMID:15249051 -1.6.99.1 n-ethylmaleimide bacillus subtilis 8.07 8.07 3 PMID:12660247;PMID:15249051 -1.6.99.1 nem shewanella oneidensis 9.54 5.819999999999999 2 PMID:16293111 -1.6.99.1 nitroglycerin bacillus subtilis 3.72 3.72 3 PMID:12660247;PMID:15249051 -1.6.99.1 nitroglycerin shewanella oneidensis 6.84 3.695 2 PMID:16293111 -1.6.99.1 trans-hex-2-enal bacillus subtilis 4.68 4.68 3 PMID:12660247;PMID:15249051 -1.7.1.1 ferricyanide arabidopsis thaliana 835.0 835.0 1 PMID:15897195 -1.7.1.1 ferricyanide spinacia oleracea 1300.0 1300.0 1 PMID:12051681 -1.7.1.1 ferricyanide zea mays 897.0 897.0 1 PMID:15897195 -1.7.1.1 ferricytochrome c spinacia oleracea 1.5 1.5 1 PMID:12051681 -1.7.1.1 nadh arabidopsis thaliana 210.0 210.0 1 PMID:15897195 -1.7.1.1 nadh spinacia oleracea 1400.0 700.7 2 PMID:12051681 -1.7.1.1 nadh zea mays 200.0 200.0 1 PMID:15897195 -1.7.1.1 nitrate arabidopsis thaliana 69.0 33.0 5 PMID:20690630;PMID:30884848 -1.7.1.1 nitrate spinacia oleracea 2.5 2.15 2 PMID:12139973 -1.7.1.11 nadph rattus norvegicus 2.5 2.5 1 PMID:3152268 -1.7.1.13 2-amino-5-cyanopyrrolo[2,3-d]pyrimidin-4-one escherichia coli 0.11 0.11 1 PMID:23595998 -1.7.1.13 5-cyanopyrrolo[2,3-d]pyrimidin-4-one escherichia coli 0.05 0.05 1 PMID:23595998 -1.7.1.13 7-cyano-7-carba-2-deaminoguanine escherichia coli 0.14 0.14 1 PMID:27754868 -1.7.1.13 7-cyano-7-carbaguanine escherichia coli 0.12 0.12 1 PMID:27754868 -1.7.1.13 7-cyano-7-carbaguanine pectobacterium carotovorum subsp. carotovorum 0.024 0.024 1 * -1.7.1.13 7-cyano-7-deazaguanine escherichia coli 0.127 0.127 1 PMID:23410922 -1.7.1.13 nadph escherichia coli 0.142 0.01 3 PMID:15767583;PMID:23410922;PMID:23595998 -1.7.1.13 nadph pectobacterium carotovorum subsp. carotovorum 0.025 0.025 1 * -1.7.1.14 no fusarium oxysporum 1200.0 1200.0 1 PMID:7829493 -1.7.1.14 no histoplasma capsulatum 83.3 83.3 1 PMID:18804446 -1.7.1.15 nitrite arabidopsis thaliana 137.5 10.8 4 PMID:30884848 -1.7.1.16 (2e)-2-[(5-nitrofuran-2-yl)methylidene]hydrazine-1-carboxamide gluconobacter oxydans 0.1 0.1 1 PMID:27138989 -1.7.1.16 1,3-dinitrobenzene gluconobacter oxydans 0.24 0.24 1 PMID:27138989 -1.7.1.16 2-chloro-6-nitrotoluene psychrobacter sp. ant206 66.82 66.82 1 PMID:31615682 -1.7.1.16 2-chloronitrobenzene gluconobacter oxydans 0.15 0.15 1 PMID:27138989 -1.7.1.16 2-nitrotoluene psychrobacter sp. ant206 70.45 70.45 1 PMID:31615682 -1.7.1.16 3-bromo-4-nitrotoluene psychrobacter sp. ant206 64.25 64.25 1 PMID:31615682 -1.7.1.16 3-nitrotoluene gluconobacter oxydans 0.18 0.18 1 PMID:27138989 -1.7.1.16 4-chloronitrobenzene gluconobacter oxydans 0.12 0.12 1 PMID:27138989 -1.7.1.16 4-nitrochlorobenzene psychrobacter sp. ant206 87.14 87.14 1 PMID:31615682 -1.7.1.16 4-nitrophenol psychrobacter sp. ant206 223.59 223.59 1 PMID:31615682 -1.7.1.16 4-nitrotoluene gluconobacter oxydans 0.13 0.13 1 PMID:27138989 -1.7.1.16 5-(aziridin-1-yl)-2,4-dinitrobenzamide gluconobacter oxydans 1.06 1.06 1 PMID:27138989 -1.7.1.16 nadph gluconobacter oxydans 1.05 1.05 1 PMID:27138989 -1.7.1.16 nitrobenzene gluconobacter oxydans 0.18 0.18 1 PMID:27138989 -1.7.1.16 nitrobenzene psychrobacter sp. ant206 256.54 256.54 1 PMID:31615682 -1.7.1.17 1,2-naphthoquinone halalkalibacter wakoensis 111.0 111.0 1 PMID:31967777 -1.7.1.17 1,4-naphthoquinone halalkalibacter wakoensis 340.0 340.0 1 PMID:31967777 -1.7.1.17 menadione halalkalibacter wakoensis 387.0 387.0 1 PMID:31967777 -1.7.1.17 methyl red shewanella oneidensis 33860.0 33860.0 1 PMID:29100166 -1.7.1.17 nadh shewanella oneidensis 33900.0 33900.0 1 PMID:29100166 -1.7.1.17 orange i halalkalibacter wakoensis 0.85 0.85 1 PMID:31967777 -1.7.1.2 nadph chlorolobion braunii 470.0 470.0 1 PMID:7200426 -1.7.1.3 ferricyanide ogataea angusta 618.0 618.0 1 PMID:15897195 -1.7.1.3 nadh neurospora crassa 290.0 290.0 1 PMID:9750171 -1.7.1.3 nadph neurospora crassa 1400.0 1400.0 1 PMID:9750171 -1.7.1.3 nadph ogataea angusta 215.0 215.0 1 PMID:15897195 -1.7.1.4 no2- neurospora crassa 130.0 130.0 1 PMID:150863 -1.7.1.6 2-hydroxy-1,4-naphthoquinone cereibacter sphaeroides 345.0 345.0 1 PMID:18548247 -1.7.1.6 2-hydroxy-1,4-naphthoquinone escherichia coli 5.8 5.8 1 PMID:19666717 -1.7.1.6 2-methyl-1,4-benzoquinone escherichia coli 72.0 72.0 1 PMID:19666717 -1.7.1.6 2-methyl-1,4-naphthoquinone cereibacter sphaeroides 3278.0 3278.0 1 PMID:18548247 -1.7.1.6 9,10-dioxo-9,10-dihydroanthracene-2,6-disulfonic acid escherichia coli 2.6 2.6 1 PMID:19666717 -1.7.1.6 9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid escherichia coli 1.1 1.1 1 PMID:19666717 -1.7.1.6 anthraquinone-2,6-disulfonate cereibacter sphaeroides 211.2 211.2 1 PMID:18548247 -1.7.1.6 anthraquinone-2-sulfonate cereibacter sphaeroides 218.4 218.4 1 PMID:18548247 -1.7.1.6 balsalazide pseudomonas aeruginosa 36.8 36.8 1 PMID:20057057 -1.7.1.6 balsalzide pseudomonas aeruginosa 20.0 0.7 3 PMID:21203919 -1.7.1.6 methyl red enterococcus faecalis 59.1 59.1 1 PMID:22387379 -1.7.1.6 methyl red enterococcus faecium 17.0 17.0 2 PMID:19741272 -1.7.1.6 methyl red halomonas elongata 0.148 0.148 1 PMID:30132989 -1.7.1.6 methyl red pseudomonas aeruginosa 12.7 8.2 4 PMID:20057057;PMID:21203919 -1.7.1.6 methyl red shewanella oneidensis 102.92 92.545 2 * -1.7.1.6 nadh enterococcus faecium 10.0 10.0 2 PMID:19741272 -1.7.1.6 nadh halomonas elongata 0.148 0.148 1 PMID:30132989 -1.7.1.6 nadh pseudomonas aeruginosa 10.0 10.0 1 PMID:20057057 -1.7.1.6 nadph pseudomonas aeruginosa 33.6 33.6 1 PMID:20057057 -1.7.1.6 sulfasalazine pseudomonas aeruginosa 2.6 0.8 3 PMID:21203919 -1.7.1.7 gmp homo sapiens 0.284 0.27449999999999997 2 PMID:26731263 -1.7.1.7 gmp trypanosoma brucei brucei 0.519 0.519 1 PMID:26731263 -1.7.1.7 guanosine 5'-phosphate escherichia coli 0.28 0.28 1 PMID:21298178 -1.7.2.1 azurin pseudomonas aeruginosa 3.2 2.16 2 PMID:9256253 -1.7.2.1 ferricytochrome c pseudomonas aeruginosa 1.33 1.33 1 PMID:7893816 -1.7.2.1 ferricytochrome c b0428 candidatus jettenia caeni 1.9 1.9 1 PMID:32248970 -1.7.2.1 ferricytochrome c551 geobacillus kaustophilus 796.0 796.0 1 PMID:24440558 -1.7.2.1 ferricytochrome c551 pseudomonas aeruginosa 2.8 1.6915 2 PMID:9256253 -1.7.2.1 ferrocytochrome c-551 pseudomonas aeruginosa 0.025 0.025 1 PMID:11226222 -1.7.2.1 ferrocytochrome c2 cereibacter sphaeroides 5.0 5.0 1 PMID:16622064 -1.7.2.1 ferrocytochrome v(gamma) cereibacter sphaeroides 0.1 0.1 1 PMID:16622064 -1.7.2.1 hydroxylamine paracoccus pantotrophus 6.4 3.1 6 PMID:11709555;PMID:12556530 -1.7.2.1 nh2oh paracoccus pantotrophus 6.4 3.0 5 PMID:11709555 -1.7.2.1 nh2oh pseudomonas denitrificans (nom. rej.) 2.58 2.58 1 PMID:5354021 -1.7.2.1 nitrite achromobacter xylosoxidans 172.0 172.0 1 PMID:15475344 -1.7.2.1 nitrite alcaligenes faecalis 1478.0 392.0 5 PMID:15301545 -1.7.2.1 nitrite homo sapiens 0.1 0.1 1 PMID:24500710 -1.7.2.1 nitrite hyphomicrobium denitrificans 320.0 320.0 1 PMID:12121770 -1.7.2.1 nitrite mycobacterium tuberculosis 100.0 100.0 1 PMID:34615967 -1.7.2.1 nitrite nitrososphaera viennensis 3.1 3.1 2 PMID:30318500 -1.7.2.1 nitrite paracoccus pantotrophus 144.0 23.15 8 PMID:11709555;PMID:12556530 -1.7.2.1 nitrite pseudomonas aeruginosa 8.0 8.0 1 PMID:11226222 -1.7.2.1 nitrite pseudomonas chlororaphis 243.0 121.81 2 PMID:15182351 -1.7.2.1 nitrite ralstonia pickettii 2.6 2.3 3 PMID:32051772 -1.7.2.1 no alcaligenes faecalis 125.0 86.5 4 PMID:15301545 -1.7.2.1 no2- paracoccus pantotrophus 144.0 41.0 7 PMID:11709555 -1.7.2.1 no2- paramagnetospirillum magnetotacticum 80.0 80.0 1 PMID:7588814 -1.7.2.1 no2- pseudomonas aeruginosa 80.0 44.0 2 PMID:11226222 -1.7.2.1 no2- pseudomonas denitrificans (nom. rej.) 9.68 9.68 1 PMID:5354021 -1.7.2.1 o2 paracoccus pantotrophus 6.4 2.8 11 PMID:11709555;PMID:12556530 -1.7.2.1 o2 pseudomonas denitrificans (nom. rej.) 1.48 1.48 1 PMID:5354021 -1.7.2.1 reduced ascorbate pseudomonas aeruginosa 7.0 7.0 1 PMID:12509983 -1.7.2.2 hydroxylamine escherichia coli 3160.0 3160.0 1 PMID:25658043 -1.7.2.2 hydroxylamine wolinella succinogenes 215.0 215.0 1 PMID:25658043 -1.7.2.2 nitric oxide escherichia coli 390.0 390.0 1 PMID:11960983 -1.7.2.2 nitrite desulfovibrio desulfuricans 340.0 340.0 1 PMID:17207484 -1.7.2.2 nitrite escherichia coli 1350.0 1025.0 2 PMID:18245085;PMID:25658043 -1.7.2.2 nitrite shewanella oneidensis 7.0 7.0 1 PMID:23210513 -1.7.2.2 nitrite thioalkalivibrio nitratireducens 2860.0 2027.5 2 PMID:22281743 -1.7.2.2 nitrite wolinella succinogenes 758.0 758.0 1 PMID:25658043 -1.7.2.2 no radical escherichia coli 840.0 840.0 1 PMID:18245085 -1.7.2.2 reduced diquat desulfovibrio desulfuricans 1064.0 1064.0 1 PMID:20689707 -1.7.2.2 reduced methyl viologen desulfovibrio desulfuricans 738.0 738.0 1 PMID:20689707 -1.7.2.2 reduced phenosafranine desulfovibrio desulfuricans 79.0 79.0 1 PMID:20689707 -1.7.2.2 sulfite thioalkalivibrio nitratireducens 0.039 0.031 2 PMID:22281743 -1.7.2.3 2-chloropyridine n-oxide escherichia coli 101.0 101.0 1 PMID:8639717 -1.7.2.3 3-hydroxypyridine n-oxide escherichia coli 49.2 49.2 1 PMID:8639717 -1.7.2.3 3-picoline n-oxide escherichia coli 137.0 137.0 1 PMID:8639717 -1.7.2.3 4-chloropyridine n-oxide escherichia coli 66.7 66.7 1 PMID:8639717 -1.7.2.3 4-methylmorpholine n-oxide escherichia coli 96.5 71.4 3 PMID:10216869;PMID:8639717 -1.7.2.3 4-methylmorpholine n-oxide shewanella massilia 109.0 109.0 1 PMID:9813127 -1.7.2.3 alpha-picoline n-oxide escherichia coli 102.0 84.2 3 PMID:10216869;PMID:8639717 -1.7.2.3 alpha-picoline n-oxide shewanella massilia 78.0 78.0 1 PMID:9813127 -1.7.2.3 dibutylsulfoxide shewanella massilia 4.0 4.0 1 PMID:9813127 -1.7.2.3 dimethylsulfoxide escherichia coli 40.2 40.2 1 PMID:10216869 -1.7.2.3 dimethylsulfoxide shewanella massilia 4.0 4.0 1 PMID:9813127 -1.7.2.3 diphenylsulfoxide escherichia coli 26.8 26.8 1 PMID:10216869 -1.7.2.3 diphenylsulfoxide shewanella massilia 4.0 4.0 1 PMID:9813127 -1.7.2.3 dl-methionine sulfoxide shewanella massilia 4.0 4.0 1 PMID:9813127 -1.7.2.3 gamma-picoline n-oxide escherichia coli 57.2 55.7 3 PMID:10216869;PMID:8639717 -1.7.2.3 hydroxylamine n-oxide escherichia coli 70.6 70.0 3 PMID:10216869;PMID:8639717 -1.7.2.3 n,n-dimethyldodecylamine n-oxide escherichia coli 155.0 155.0 1 PMID:8639717 -1.7.2.3 n,n-dimethyldodecylamine n-oxide shewanella massilia 151.0 151.0 1 PMID:9813127 -1.7.2.3 n,n-dimethylhexylamine n-oxide escherichia coli 13.8 13.8 1 PMID:8639717 -1.7.2.3 n-cyclohexyldimethylamine n-oxide escherichia coli 45.6 45.6 1 PMID:8639717 -1.7.2.3 pyridine n-oxide escherichia coli 53.5 44.7 3 PMID:10216869;PMID:8639717 -1.7.2.3 tetramethylene sulfoxide escherichia coli 56.0 56.0 1 PMID:10216869 -1.7.2.3 trimethylamine n-oxide escherichia coli 258.0 132.5 4 PMID:10216869;PMID:8639717 -1.7.2.3 trimethylamine n-oxide shewanella massilia 120.0 120.0 1 PMID:9813127 -1.7.2.4 n2o pyrobaculum aerophilum 8.0 8.0 1 PMID:20597980 -1.7.2.4 reduced benzyl viologen achromobacter cycloclastes 162.9 162.9 1 PMID:22910335 -1.7.2.4 reduced pseudoazurin achromobacter cycloclastes 89.3 89.3 1 PMID:22910335 -1.7.2.5 nitric oxide nitratidesulfovibrio vulgaris 12.0 12.0 1 PMID:15736966 -1.7.2.5 nitric oxide paracoccus denitrificans 40.0 40.0 1 PMID:16417518 -1.7.2.5 no aspergillus oryzae 166.7 166.7 1 PMID:15502348 -1.7.2.5 no escherichia coli 14.9 14.9 1 PMID:12101220 -1.7.2.5 no fusarium lichenicola 667.0 533.0 3 PMID:9074619 -1.7.2.5 no fusarium oxysporum 525.0 368.0 2 PMID:9074619;PMID:9602081 -1.7.2.5 no neomoorella thermoacetica 48.0 48.0 1 PMID:15850383 -1.7.2.5 no paracoccus denitrificans 33.33 33.33 1 PMID:14766741 -1.7.2.5 no schinkia azotoformans 150.0 134.0 2 PMID:15491156 -1.7.2.5 pseudoazurin paracoccus denitrificans 70.38 15.0 3 PMID:16961460 -1.7.2.6 ferricyanide nitrosococcus oceani 111.0 111.0 1 PMID:21576859 -1.7.2.6 ferricytochrome c-554 nitrosococcus oceani 3.4 3.4 1 PMID:21576859 -1.7.2.6 hydroxylamine candidatus methylacidiphilum fumarolicum 7.2 7.2 1 PMID:32913059 -1.7.2.6 hydroxylamine nitrosomonas europaea 383.0 383.0 1 PMID:698180 -1.7.2.6 hydroxylamine nitrososphaera viennensis 0.039 0.039 1 PMID:30318500 -1.7.2.6 nitrite nitrosomonas europaea 158.0 158.0 1 PMID:698180 -1.7.2.8 hydrazine candidatus brocadia fulgida 1.7 1.7 1 PMID:33798263 -1.7.2.8 hydrazine candidatus kuenenia stuttgartensis 6.0 6.0 1 PMID:27317665 -1.7.2.9 hydrazine candidatus kuenenia stuttgartensis 4.9 4.9 1 PMID:24302732 -1.7.2.9 hydroxylamine candidatus kuenenia stuttgartensis 15.0 15.0 1 PMID:24302732 -1.7.2.9 hydroxylamine candidatus methylacidiphilum fumarolicum 7.2 7.2 1 PMID:32913059 -1.7.3.1 1-nitrohexane fusarium oxysporum 2.0 2.0 1 PMID:19265437 -1.7.3.1 1-nitrooctane fusarium oxysporum 4.4 4.4 1 PMID:19265437 -1.7.3.1 1-nitropropane pseudomonas aeruginosa 0.024 0.024 1 PMID:29885842 -1.7.3.1 nitroethane fusarium oxysporum 15.0 15.0 4 PMID:19265437;PMID:20056514;PMID:23660407;PMID:28529198 -1.7.3.1 nitroethane podospora anserina 15.0 15.0 1 PMID:20481475 -1.7.3.1 nitroethane pseudomonas aeruginosa 0.031 0.031 1 PMID:29885842 -1.7.3.1 o2 podospora anserina 15.0 15.0 1 PMID:20481475 -1.7.3.3 h2o2 aspergillus flavus 9.3 9.3 1 PMID:27702489 -1.7.3.3 urate arthrobacter globiformis 6.64 6.64 1 PMID:31253939 -1.7.3.3 urate aspergillus flavus 18.1 18.1 1 PMID:12413448 -1.7.3.3 urate canis lupus familiaris 13.6 13.6 1 PMID:22481018 -1.7.3.3 urate cytobacillus firmus 21800.0 21800.0 1 PMID:25981580 -1.7.3.3 urate kluyveromyces marxianus 32.74 32.74 1 PMID:30221113 -1.7.3.3 urate latimeria menadoensis 29.89 29.89 1 PMID:30871218 -1.7.3.3 urate microbacterium sp. 3.01 3.01 1 * -1.7.3.3 uric acid glycine max 31.3 31.3 1 PMID:9709003 -1.7.3.5 3-aci-nitropropanoate penicillium atrovenetum 350.0 350.0 1 PMID:3667582 -1.7.3.6 hydroxylamine paracoccus denitrificans 0.53 0.53 1 PMID:8920986 -1.7.5.1 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinol escherichia coli 68.0 68.0 1 PMID:9576848 -1.7.5.1 5-hydroxy-2-methyl-1,4-naphthoquinol escherichia coli 120.0 120.0 1 PMID:9576848 -1.7.5.1 nitrate escherichia coli 68.0 68.0 1 PMID:15615728 -1.7.5.2 nitric oxide schinkia azotoformans 153.0 134.0 4 PMID:15491156 -1.7.7.1 nitrite chlamydomonas reinhardtii 14.6 7.975 2 PMID:19586916 -1.7.7.1 nitrite cucurbita pepo 89.0 89.0 1 * -1.7.7.1 nitrite cyanidioschyzon merolae 3.77 2.935 2 PMID:28057796 -1.7.7.1 nitrite nicotiana tabacum 200.0 136.5 2 PMID:22238192 -1.7.7.1 nitrite pyropia yezoensis 10.0 10.0 1 * -1.7.7.1 nitrite scenedesmus fuscus 54.0 54.0 1 * -1.7.7.1 nitrite spinacia oleracea 110.0 110.0 1 * -1.7.7.1 nitrite synechocystis sp. pcc 6803 666.0 573.0 2 PMID:19586916 -1.7.7.1 reduced ferredoxin synechocystis sp. 138.2 138.2 1 PMID:22427434 -1.7.7.2 nitrate synechococcus elongatus pcc 7942 = fachb-805 1090.0 1090.0 1 * -1.7.7.2 nitrate synechococcus sp. 80.0 80.0 1 PMID:15166246 -1.7.99.1 hydroxylamine pyrococcus furiosus 3.8 3.8 1 PMID:19241093 -1.8.1.10 coa disulfide staphylococcus aureus 1100.0 1100.0 1 PMID:9488708 -1.8.1.12 (e,z)-ajoene trypanosoma cruzi 0.67 0.67 1 PMID:9986706 -1.8.1.12 1,4-benzoquinone trypanosoma congolense 4.8 4.8 1 PMID:7548022 -1.8.1.12 4-aminobutyryl-l-cysteinylglycyl-3-dimethylaminopropylamide disulfide crithidia fasciculata 21.8 21.8 1 PMID:8105896 -1.8.1.12 5,5'-dithiobis(n-[3-(4-methylpiperazin-1-yl)propyl]-2-nitrobenzamide) trypanosoma cruzi 125.0 125.0 1 PMID:10036154 -1.8.1.12 5,5'-dithiobis(n-[3-(dimethylamino)propyl]-2-nitrobenzamide) trypanosoma cruzi 125.0 125.0 1 PMID:10036154 -1.8.1.12 9,10-phenanthrenequinone trypanosoma congolense 2.9 2.9 1 PMID:7548022 -1.8.1.12 deazatrypanothione disulfide trypanosoma congolense 83.3 83.3 1 PMID:2669965 -1.8.1.12 glutathionylspermidine disulfide euglena gracilis 242.0 242.0 1 PMID:9923598 -1.8.1.12 glutathionylspermidine disulfide trypanosoma cruzi 85.4 85.4 1 PMID:7737173 -1.8.1.12 l-beta-aspartyl-l-cysteinylglycyl-3-dimethylaminopropylamide disulfide crithidia fasciculata 61.3 61.3 1 PMID:8105896 -1.8.1.12 l-cysteinylglycyl-3-dimethylaminopropylamide disulfide crithidia fasciculata 53.2 53.2 1 PMID:8105896 -1.8.1.12 l-gamma-glutamyl-l-cysteinylglycyl-3-dimethylaminopropylamide disulfide crithidia fasciculata 818.0 818.0 1 PMID:8105896 -1.8.1.12 n-benzyloxycarbonyl-l-cysteinylglycyl-3-dimethylaminopropylamide disulfide crithidia fasciculata 109.0 109.0 1 PMID:8105896 -1.8.1.12 nadph trypanosoma cruzi 6.33 6.33 1 PMID:7737173 -1.8.1.12 tert-butyloxycarbonyl-l-cysteinylglycyl-3-dimethylaminopropylamide disulfide crithidia fasciculata 101.0 101.0 1 PMID:8105896 -1.8.1.12 thio-nadph trypanosoma cruzi 7.02 7.02 1 PMID:7737173 -1.8.1.12 trypanothione disulfide crithidia fasciculata 517.0 517.0 1 PMID:3718941 -1.8.1.12 trypanothione disulfide euglena gracilis 283.0 283.0 1 PMID:9923598 -1.8.1.12 trypanothione disulfide homo sapiens 20.8 20.8 1 PMID:9174360 -1.8.1.12 trypanothione disulfide leishmania donovani 179.0 98.59 2 PMID:15766869;PMID:7607216 -1.8.1.12 trypanothione disulfide leishmania infantum 30.2 18.5 4 PMID:23733388;PMID:23744811 -1.8.1.12 trypanothione disulfide trypanosoma brucei 46.8 46.8 1 PMID:19747949 -1.8.1.12 trypanothione disulfide trypanosoma congolense 160.0 141.0 2 PMID:2669965;PMID:7548022 -1.8.1.12 trypanothione disulfide trypanosoma cruzi 240.0 237.0 3 PMID:10036154;PMID:3549299;PMID:7737173 -1.8.1.13 bis-gamma-glutamylcystine halobacterium salinarum 54.0 54.0 1 PMID:23560638 -1.8.1.13 fad halobacterium salinarum 28.3 28.3 1 PMID:2910862 -1.8.1.14 coa-disulfide pyrococcus horikoshii 5.43 4.915 2 PMID:29988575 -1.8.1.14 coa-disulfide staphylococcus aureus 27.0 15.085 2 PMID:17258460;PMID:22954034 -1.8.1.14 coa-disulfide thermus thermophilus 5.0 5.0 1 PMID:31520616 -1.8.1.14 coa-ethyl disulfide staphylococcus aureus 2.7 2.7 1 PMID:17258460 -1.8.1.14 coa-methyl disulfide staphylococcus aureus 4.3 4.3 1 PMID:17258460 -1.8.1.14 coa-sec-butyl disulfide staphylococcus aureus 0.95 0.95 1 PMID:17258460 -1.8.1.14 methyl methanethiolsulfonate staphylococcus aureus 6.4 6.4 1 PMID:22954034 -1.8.1.14 nadh bacillus anthracis 27.0 27.0 2 PMID:18399646 -1.8.1.14 nadh pyrococcus horikoshii 2.3 2.3 1 PMID:29988575 -1.8.1.14 nadh thermus thermophilus 5.0 5.0 1 PMID:31520616 -1.8.1.14 nadph bacillus anthracis 8.0 8.0 2 PMID:18399646 -1.8.1.14 nadph pyrococcus horikoshii 7.2 6.5 2 PMID:15720393;PMID:29988575 -1.8.1.15 2-(-n-acetyl-l-cysteinyl) amino-2-deoxy-alpha-d-glucopyranoside disulfide mycobacterium tuberculosis 70.05 70.05 1 PMID:18175009 -1.8.1.15 5-(benzyl 2-(n-acetyl-l-cysteinyl) amino-2-deoxy-alpha-d-glucopyranoside)-dithio-2-nitrobenzoate mycobacterium tuberculosis 115.0 115.0 1 PMID:19233116 -1.8.1.15 7-methyljuglone mycobacterium tuberculosis 0.254 0.254 1 PMID:17888665 -1.8.1.15 8-chloro-5-methoxy-7-methyl-1,4-naphthoquinone mycobacterium tuberculosis 0.435 0.435 1 PMID:17888665 -1.8.1.15 benzyl 2-(-n-acetyl-l-cysteinyl) amino-2-deoxy-alpha-d-glucopyranoside disulfide mycobacterium tuberculosis 36.99 36.99 1 PMID:18175009 -1.8.1.15 benzyl 2-(n-acetyl-l-cysteinyl) amino-2-deoxy-alpha-d-glucopyranoside disulfide mycobacterium tuberculosis 37.0 37.0 1 PMID:19233116 -1.8.1.15 diospyrin mycobacterium tuberculosis 0.033 0.033 1 PMID:17888665 -1.8.1.15 juglone mycobacterium tuberculosis 0.324 0.324 1 PMID:17888665 -1.8.1.15 menadione mycobacterium tuberculosis 0.483 0.483 1 PMID:17888665 -1.8.1.15 methyl 2-(-n-acetyl-l-cysteinyl) amino-2-deoxy-alpha-d-glucopyranoside disulfide mycobacterium tuberculosis 25.54 25.54 1 PMID:18175009 -1.8.1.15 mycothione mycobacterium tuberculosis 69.0 68.88 2 PMID:18175009;PMID:19233116 -1.8.1.15 nadh mycobacterium tuberculosis 30.0 25.0 2 PMID:11318633;PMID:18772286 -1.8.1.15 nadp+ mycobacterium tuberculosis 190.0 190.0 1 PMID:18772286 -1.8.1.15 nadph mycobacterium tuberculosis 129.0 129.0 1 PMID:18772286 -1.8.1.15 neodiospyrin mycobacterium tuberculosis 0.063 0.063 1 PMID:17888665 -1.8.1.15 seo32- rhodococcus erythropolis 8.29 5.46 3 PMID:33377161 -1.8.1.15 teo32- rhodococcus erythropolis 1.48 1.0 3 PMID:33377161 -1.8.1.16 glutathione amide disulfide marichromatium gracile 249.7 249.7 1 PMID:11399772 -1.8.1.16 glutathione disulfide marichromatium gracile 146.0 146.0 1 PMID:11399772 -1.8.1.16 nadh marichromatium gracile 186.8 186.8 1 PMID:11399772 -1.8.1.16 nadph marichromatium gracile 0.14 0.14 1 PMID:11399772 -1.8.1.2 fad escherichia coli 150.0 150.0 1 * -1.8.1.2 hydroxylamine escherichia coli 217.0 217.0 1 PMID:4150390 -1.8.1.2 nadp+ escherichia coli 605.0 605.0 1 PMID:4150390 -1.8.1.2 nadph escherichia coli 468.0 245.0 6 PMID:4150390 -1.8.1.2 nitrite escherichia coli 51.7 51.7 1 PMID:4150390 -1.8.1.2 reduced methyl viologen escherichia coli 605.0 605.0 1 PMID:4150390 -1.8.1.2 sulfite escherichia coli 65.0 52.5 2 PMID:4150390 -1.8.1.20 4,4'-disulfanediyldibutanoate rhodococcus erythropolis 2.5 2.5 1 PMID:27564089 -1.8.1.22 hydroxylamine nitratidesulfovibrio vulgaris 29.0 29.0 1 PMID:8033912 -1.8.1.22 nitrite nitratidesulfovibrio vulgaris 0.038 0.038 1 PMID:8033912 -1.8.1.22 sulfite nitratidesulfovibrio vulgaris 0.31 0.31 1 PMID:8033912 -1.8.1.4 (r,s)-lipoamide lathyrus oleraceus 190.0 190.0 1 PMID:10806385 -1.8.1.4 1,4-benzoquinone streptomyces seoulensis 108.0 108.0 1 PMID:9858775 -1.8.1.4 2,6-dimethyl-1,4-benzoquinone mycobacterium tuberculosis 190.0 190.0 1 PMID:12590611 -1.8.1.4 dihydrolipoamide homo sapiens 899.0 567.0 7 PMID:10336857;PMID:17171578;PMID:17960497 -1.8.1.4 dihydrolipoamide leishmania donovani 0.122 0.067 2 PMID:29466712 -1.8.1.4 dihydrolipoamide plasmodium falciparum 448.0 279.0 2 PMID:15612914;PMID:25387830 -1.8.1.4 dl-lipoylpentanoate mycobacterium tuberculosis 220.0 220.0 1 PMID:12590611 -1.8.1.4 lipoamide homo sapiens 649.0 519.0 3 PMID:10336857;PMID:17171578 -1.8.1.4 lipoamide plasmodium falciparum 337.0 217.0 2 PMID:15612914;PMID:25387830 -1.8.1.4 lipoamide streptomyces seoulensis 88.0 88.0 1 PMID:9858775 -1.8.1.4 lipoic acid streptomyces seoulensis 70.0 70.0 1 PMID:9858775 -1.8.1.4 lipoyl h-protein lathyrus oleraceus 345.0 345.0 1 PMID:10806385 -1.8.1.4 nad+ homo sapiens 899.0 899.0 3 PMID:10336857 -1.8.1.4 nad+ leishmania donovani 0.0045 0.0036 2 PMID:29466712 -1.8.1.4 nad+ plasmodium falciparum 337.0 223.5 2 PMID:15612914;PMID:25387830 -1.8.1.4 nad+ streptococcus pneumoniae 506.0 223.0 3 PMID:17690105 -1.8.1.4 nadh homo sapiens 340.0 340.0 1 PMID:10336857 -1.8.1.4 nadh plasmodium falciparum 448.0 262.9 2 PMID:15612914;PMID:25387830 -1.8.1.4 o2 mycobacterium tuberculosis 0.25 0.25 1 PMID:12590611 -1.8.1.4 ubiquinone sus scrofa 300.0 186.0 2 PMID:11231302 -1.8.1.5 2-(2-oxopropylthio)ethanesulfonate xanthobacter autotrophicus 0.22 0.22 1 PMID:21764916 -1.8.1.5 acetoacetate xanthobacter sp. 0.263 0.263 1 PMID:10684609 -1.8.1.6 l-cystine homo sapiens 30.3 30.3 1 PMID:24778250 -1.8.1.7 (e)-ajoene homo sapiens 1.47 0.905 2 PMID:9986706 -1.8.1.7 (z)-ajoene homo sapiens 2.6 2.6 1 PMID:9986706 -1.8.1.7 1,4-dihydroxy-9,10-anthraquinone plasmodium falciparum 0.11 0.11 1 PMID:19919822 -1.8.1.7 1,4-naphthoquinone homo sapiens 1.08 1.08 1 PMID:18633531 -1.8.1.7 1,4-naphthoquinone plasmodium falciparum 1.08 1.04 2 PMID:18633531;PMID:19919822 -1.8.1.7 1,8-dihydroxy-9,10-anthraquinone plasmodium falciparum 0.1 0.1 1 PMID:19919822 -1.8.1.7 2,5-bis(aziridin-1-yl)cyclohexa-2,5-diene-1,4-dione plasmodium falciparum 5.0 5.0 1 PMID:19919822 -1.8.1.7 2,6-dimethyl-1,4-benzoquinone plasmodium falciparum 1.1 1.1 1 PMID:19919822 -1.8.1.7 2-methyl-1,4-naphthoquinone plasmodium falciparum 0.14 0.14 1 PMID:19919822 -1.8.1.7 5,5'-dithiobis(2-nitrobenzoic acid) schistosoma mansoni 16.0 8.6 2 PMID:18300227 -1.8.1.7 5,8-dihydroxy-1,4-naphthoquinone plasmodium falciparum 7.0 7.0 1 PMID:19919822 -1.8.1.7 5-hydroxy-1,4-naphthoquinone plasmodium falciparum 5.5 5.5 1 PMID:19919822 -1.8.1.7 6,7-dimethylquinoline-5,8-dione homo sapiens 0.11 0.11 1 PMID:18633531 -1.8.1.7 6,7-dimethylquinoline-5,8-dione plasmodium falciparum 0.08 0.08 1 PMID:18633531 -1.8.1.7 6-methylquinoline-5,8-dione homo sapiens 0.35 0.35 1 PMID:18633531 -1.8.1.7 6-methylquinoline-5,8-dione plasmodium falciparum 0.35 0.35 1 PMID:18633531 -1.8.1.7 7-methylquinoline-5,8-dione homo sapiens 0.13 0.13 1 PMID:18633531 -1.8.1.7 7-methylquinoline-5,8-dione plasmodium falciparum 0.39 0.39 1 PMID:18633531 -1.8.1.7 9,10-phenanthrene quinone plasmodium falciparum 0.22 0.22 1 PMID:19919822 -1.8.1.7 diallyl trisulfide homo sapiens 0.16 0.16 1 PMID:9986706 -1.8.1.7 diethyl [2,5-bis(aziridin-1-yl)-3,6-dioxocyclohexa-1,4-diene-1,4-diyl]biscarbamate plasmodium falciparum 0.1 0.1 1 PMID:19919822 -1.8.1.7 glutathione disulfide escherichia coli 548.7 548.7 1 PMID:8526857 -1.8.1.7 glutathione disulfide haemonchus contortus 2.95 2.95 1 PMID:28456691 -1.8.1.7 glutathione disulfide homo sapiens 165.0 106.65 2 PMID:11705998 -1.8.1.7 glutathione disulfide ipomoea batatas 50.14 50.14 1 PMID:19358534 -1.8.1.7 glutathione disulfide neospora caninum 0.076 0.076 1 PMID:34310993 -1.8.1.7 glutathione disulfide plasmodium falciparum 120.0 120.0 1 PMID:11705998 -1.8.1.7 glutathione disulfide populus trichocarpa 23.43 19.57 3 PMID:32234218 -1.8.1.7 glutathione disulfide psychrobacter sp. ant206 95.78 95.78 1 PMID:31936518 -1.8.1.7 gssg escherichia coli 733.3 733.3 1 PMID:1924337 -1.8.1.7 gssg euglena gracilis 317.0 317.0 1 PMID:9923598 -1.8.1.7 gssg homo sapiens 210.0 210.0 2 PMID:1924337;PMID:9174360;PMID:9277 -1.8.1.7 gssg schistosoma mansoni 0.19 0.19 1 PMID:18300227 -1.8.1.7 menadione homo sapiens 0.16 0.16 1 PMID:18633531 -1.8.1.7 menadione plasmodium falciparum 0.16 0.16 1 PMID:18633531 -1.8.1.7 n1-monoglutathionylspermidine glutathione disulfide escherichia coli 405.8 405.8 1 PMID:8526857 -1.8.1.7 nadh anabaena sp. 38.0 38.0 1 PMID:10024475 -1.8.1.7 nadh xanthomonas campestris 32.5 32.5 1 PMID:15883020 -1.8.1.7 nadph anabaena sp. 367.0 367.0 1 PMID:10024475 -1.8.1.7 nadph colwellia psychrerythraea 700.0 458.5 2 PMID:26101017 -1.8.1.7 nadph ipomoea batatas 53.72 53.72 1 PMID:19358534 -1.8.1.7 nadph neospora caninum 0.08 0.08 1 PMID:34310993 -1.8.1.7 nadph populus trichocarpa 29.28 14.08 3 PMID:32234218 -1.8.1.7 nadph psychrobacter sp. ant206 95.78 95.78 1 PMID:31936518 -1.8.1.7 nadph saccharomyces cerevisiae 900.0 681.65 2 PMID:17554778 -1.8.1.7 nadph xanthomonas campestris 37.5 37.5 1 PMID:15883020 -1.8.1.7 quinoline-5,8-dione homo sapiens 2.23 2.23 1 PMID:18633531 -1.8.1.7 quinoline-5,8-dione plasmodium falciparum 1.55 1.55 1 PMID:18633531 -1.8.1.7 quinoxaline-5,8-dione homo sapiens 0.34 0.34 1 PMID:18633531 -1.8.1.7 quinoxaline-5,8-dione plasmodium falciparum 0.35 0.35 1 PMID:18633531 -1.8.1.7 tetramethyl-1,4-benzoquinone plasmodium falciparum 0.3 0.3 1 PMID:19919822 -1.8.1.7 trimethyl-1,4-benzoquinone plasmodium falciparum 0.2 0.2 1 PMID:19919822 -1.8.1.7 trypanothione escherichia coli 101.7 101.7 1 PMID:1924337 -1.8.1.7 trypanothione homo sapiens 20.8 10.48 2 PMID:1924337;PMID:9174360 -1.8.1.8 2,6-dimethyl-1,4-benzoquinone mycobacterium tuberculosis 2.8 1.4038499999999998 2 PMID:15456792 -1.8.1.8 5-hydroxy-1,4-naphthoquinone mycobacterium tuberculosis 2.5 1.25395 2 PMID:15456792 -1.8.1.8 nad(p)h mycobacterium tuberculosis 0.0087 0.0087 1 PMID:15456792 -1.8.1.8 nadh mycobacterium tuberculosis 3.6 2.8 3 PMID:15456792 -1.8.1.8 nadph mycobacterium tuberculosis 0.0079 0.0078000000000000005 2 PMID:15456792 -1.8.1.8 thio-nad+ mycobacterium tuberculosis 3.6 1.8043500000000001 2 PMID:15456792 -1.8.1.9 5,5'-dithio-bis(2-nitrobenzoic acid) babesia bovis 10.8 10.8 1 PMID:24239559 -1.8.1.9 5,5'-dithio-bis(2-nitrobenzoic acid) euglena gracilis 10.7 5.79 2 PMID:26025518 -1.8.1.9 5,5'-dithio-bis(2-nitrobenzoic acid) haemonchus contortus 11.96 11.96 1 PMID:23248236 -1.8.1.9 5,5'-dithio-bis(2-nitrobenzoic acid) meleagris gallopavo 87.8 87.8 1 * -1.8.1.9 5,5'-dithiobis(2-nitrobenzoic acid) aeropyrum pernix 9.0 9.0 1 PMID:12423340 -1.8.1.9 5,5'-dithiobis(2-nitrobenzoic acid) anopheles gambiae 5.5 5.5 1 PMID:14622292 -1.8.1.9 5,5'-dithiobis(2-nitrobenzoic acid) caenorhabditis elegans 2.53 2.23 3 PMID:16780799;PMID:18986163 -1.8.1.9 5,5'-dithiobis(2-nitrobenzoic acid) drosophila melanogaster 21.6 2.62 5 PMID:17385893;PMID:17661444;PMID:18986163 -1.8.1.9 5,5'-dithiobis(2-nitrobenzoic acid) entamoeba histolytica 0.25 0.24 2 PMID:22967759 -1.8.1.9 5,5'-dithiobis(2-nitrobenzoic acid) homo sapiens 33.33 18.73 5 PMID:16750198;PMID:21172426 -1.8.1.9 5,5'-dithiobis(2-nitrobenzoic acid) medicago truncatula 0.62 0.62 2 PMID:17185738 -1.8.1.9 5,5'-dithiobis(2-nitrobenzoic acid) mus musculus 48.42 20.85 3 PMID:17385893;PMID:18986163 -1.8.1.9 5,5'-dithiobis(2-nitrobenzoic acid) rattus norvegicus 106.3 70.3 3 PMID:19054767;PMID:19146949 -1.8.1.9 5,5'-dithiobis(2-nitrobenzoic acid) schistosoma mansoni 16.0 8.6 2 PMID:18300227 -1.8.1.9 5,5'-dithiobis(2-nitrobenzoic acid) solanum lycopersicum 1.77 1.77 1 PMID:22027005 -1.8.1.9 5-hydroxy-1,4-naphthoquinone rattus norvegicus 24.1 24.1 1 PMID:19054767 -1.8.1.9 alloxan bos taurus 167.0 167.0 1 PMID:6933551 -1.8.1.9 arabidopsis thaliana thioredoxin 3 arabidopsis thaliana 5.9 5.9 1 PMID:24123219 -1.8.1.9 arabidopsis thaliana thioredoxin 3 hordeum vulgare subsp. vulgare 4.8 4.8 1 PMID:24123219 -1.8.1.9 babesia bovis thioredoxin babesia bovis 20.0 20.0 1 PMID:24239559 -1.8.1.9 dtnb homo sapiens 29.5 29.5 1 PMID:8577704 -1.8.1.9 dtnb plasmodium falciparum 4.58 4.58 1 PMID:9368022 -1.8.1.9 dtnb rattus norvegicus 66.7 66.7 1 PMID:7159551 -1.8.1.9 ebsulfur escherichia coli 11.7 11.7 1 PMID:23248236 -1.8.1.9 ebsulfur disulfide escherichia coli 1.7 1.7 1 PMID:23248236 -1.8.1.9 escherichia coli thioredoxin babesia bovis 4.1 4.1 1 PMID:24239559 -1.8.1.9 escherichia coli thioredoxin hordeum vulgare subsp. vulgare 9.4 9.4 1 PMID:24123219 -1.8.1.9 fad escherichia coli 33.0 33.0 1 PMID:8664260 -1.8.1.9 glutaredoxin 4 escherichia coli 8.0 8.0 1 PMID:15833738 -1.8.1.9 gssg taenia crassiceps 5.1 5.1 1 PMID:14668013 -1.8.1.9 hordeum vulgare thioredoxin 1 hordeum vulgare subsp. vulgare 12.1 12.1 1 PMID:24123219 -1.8.1.9 hordeum vulgare thioredoxin 2 arabidopsis thaliana 8.5 8.5 1 PMID:24123219 -1.8.1.9 hordeum vulgare thioredoxin 2 hordeum vulgare subsp. vulgare 8.0 8.0 1 PMID:24123219 -1.8.1.9 hordeum vulgare thioredoxin 2 mutant e86a hordeum vulgare subsp. vulgare 5.3 5.3 1 PMID:24123219 -1.8.1.9 hordeum vulgare thioredoxin 2 mutant g57p hordeum vulgare subsp. vulgare 7.9 7.9 1 PMID:24123219 -1.8.1.9 hordeum vulgare thioredoxin 2 mutant i51g hordeum vulgare subsp. vulgare 15.9 15.9 1 PMID:24123219 -1.8.1.9 hordeum vulgare thioredoxin disulfide h1 hordeum vulgare 3.26 2.755 2 PMID:18162587 -1.8.1.9 hordeum vulgare thioredoxin disulfide h2 hordeum vulgare 2.98 1.0550000000000002 4 PMID:18162587 -1.8.1.9 hydrogen peroxide mus musculus 6.08 3.6315 2 PMID:16618105 -1.8.1.9 lipoamide homo sapiens 3.3 2.45 2 PMID:21172426 -1.8.1.9 lipoamide rattus norvegicus 3.7 3.7 1 PMID:19054767 -1.8.1.9 lipoic acid homo sapiens 1.8 1.8 1 PMID:21172426 -1.8.1.9 methaneseleninic acid mus musculus 16.05 16.05 1 PMID:21038895 -1.8.1.9 methylseleninate drosophila melanogaster 12.0 12.0 1 PMID:11782468 -1.8.1.9 methylseleninate homo sapiens 23.0 23.0 1 PMID:11782468 -1.8.1.9 methylseleninate mus musculus 14.0 14.0 1 PMID:11782468 -1.8.1.9 methylseleninate plasmodium falciparum 31.0 31.0 1 PMID:11782468 -1.8.1.9 nadh entamoeba histolytica 0.2 0.2 1 PMID:22967759 -1.8.1.9 nadh methanosarcina acetivorans 0.817 0.817 1 PMID:25112424 -1.8.1.9 nadh solanum lycopersicum 0.06 0.06 1 PMID:22027005 -1.8.1.9 nadph babesia bovis 20.0 20.0 1 PMID:24239559 -1.8.1.9 nadph entamoeba histolytica 0.25 0.25 1 PMID:22967759 -1.8.1.9 nadph euglena gracilis 6.4 3.495 2 PMID:26025518 -1.8.1.9 nadph haemonchus contortus 7.1 7.1 1 PMID:23248236 -1.8.1.9 nadph leptospira biflexa serovar patoc 4.01 4.01 1 PMID:27178006 -1.8.1.9 nadph leptospira interrogans serovar copenhageni 6.0 6.0 1 PMID:27178006 -1.8.1.9 nadph meleagris gallopavo 109.8 109.8 1 * -1.8.1.9 nadph methanosarcina acetivorans 0.65 0.65 1 PMID:25112424 -1.8.1.9 nadph saccharolobus solfataricus 0.61 0.61 1 PMID:15667938 -1.8.1.9 nadph saccharomyces cerevisiae 33.3 33.3 1 PMID:4149839 -1.8.1.9 nadph solanum lycopersicum 0.35 0.35 1 PMID:22027005 -1.8.1.9 protein disulfide-isomerase bos taurus 500.0 500.0 1 PMID:2188973 -1.8.1.9 rat thioredoxin homo sapiens 1.83 1.83 1 PMID:8577704 -1.8.1.9 selenocysteine bos taurus 1600.0 1600.0 1 PMID:10447675 -1.8.1.9 thioredoxin aeropyrum pernix 63.2 63.2 1 PMID:12423340 -1.8.1.9 thioredoxin anopheles gambiae 15.7 15.4 3 PMID:14622292 -1.8.1.9 thioredoxin bos taurus 1300.0 1200.0 3 PMID:10447675 -1.8.1.9 thioredoxin caenorhabditis elegans 10.17 6.135 2 PMID:16780799 -1.8.1.9 thioredoxin entamoeba histolytica 1.25 0.875 2 PMID:22967759 -1.8.1.9 thioredoxin escherichia coli 22.8 22.4 2 PMID:2187529;PMID:2644268 -1.8.1.9 thioredoxin homo sapiens 46.57 16.94 6 PMID:16774913;PMID:8577704 -1.8.1.9 thioredoxin mus musculus 37.88 27.25 6 PMID:16618105;PMID:16774913 -1.8.1.9 thioredoxin rattus norvegicus 50.0 45.85 2 PMID:10849437;PMID:7159551 -1.8.1.9 thioredoxin saccharolobus solfataricus 1.3 1.3 1 PMID:15667938 -1.8.1.9 thioredoxin solanum lycopersicum 0.38 0.38 1 PMID:22027005 -1.8.1.9 thioredoxin 1 saccharomyces cerevisiae 43.7 43.7 1 PMID:20235561 -1.8.1.9 thioredoxin 2 saccharomyces cerevisiae 42.9 42.9 1 PMID:20235561 -1.8.1.9 thioredoxin 3 saccharomyces cerevisiae 34.0 34.0 1 PMID:20235561 -1.8.1.9 thioredoxin 41 entamoeba histolytica 2.2 2.1 2 PMID:22967759 -1.8.1.9 thioredoxin 8 entamoeba histolytica 2.7 2.6500000000000004 2 PMID:22967759 -1.8.1.9 thioredoxin disulfide drosophila melanogaster 5.8 5.395 2 PMID:17385893;PMID:17661444 -1.8.1.9 thioredoxin disulfide leptospira biflexa serovar patoc 13.3 13.3 1 PMID:27178006 -1.8.1.9 thioredoxin disulfide leptospira interrogans serovar copenhageni 7.7 7.7 1 PMID:27178006 -1.8.1.9 thioredoxin disulfide methanosarcina acetivorans 1.175 1.175 1 PMID:25112424 -1.8.1.9 thioredoxin disulfide mus musculus 37.0 0.13 3 PMID:17385893 -1.8.1.9 thioredoxin disulfide rattus norvegicus 114.1 94.17 3 PMID:19054767;PMID:19146949 -1.8.1.9 thioredoxin disulfide schistosoma mansoni 30.0 30.0 1 PMID:18300227 -1.8.1.9 thioredoxin disulfide taenia crassiceps 19.2 19.2 1 PMID:14668013 -1.8.1.9 thioredoxin disulfide 41 entamoeba histolytica 2.2 2.2 1 PMID:18394433 -1.8.1.9 thioredoxin disulfide 8 entamoeba histolytica 1.43 1.43 1 PMID:18394433 -1.8.2.1 ferricytochrome c ancylobacter novellus 10880.0 10880.0 1 PMID:12372602 -1.8.2.1 sulfite ancylobacter novellus 10880.0 313.54999999999995 12 PMID:12372602;PMID:16893171;PMID:19004819 -1.8.2.1 sulfite homo sapiens 26.9 26.9 1 PMID:20063894 -1.8.2.2 ferricyanide allochromatium vinosum 17000.0 17000.0 1 PMID:16995898 -1.8.2.2 tetrathionate allochromatium vinosum 37.0 37.0 1 PMID:25673691 -1.8.2.2 thiosulfate acidiphilium acidophilum 250000.0 129250.0 2 * -1.8.2.2 thiosulfate allochromatium vinosum 14000.0 12500.0 4 PMID:16995898;PMID:22779704;PMID:25673691 -1.8.2.2 thiosulfate campylobacter jejuni 604.0 604.0 1 PMID:23421726 -1.8.2.2 thiosulfate thiobacillus sp. 2300.0 2300.0 1 PMID:9082913 -1.8.2.3 oxidized heart cytochrome c paracoccus pantotrophus 3.9 3.9 1 PMID:15544340 -1.8.3.1 cytochrome c gallus gallus 85.0 85.0 1 PMID:2832163 -1.8.3.1 cytochrome c homo sapiens 26.9 18.1 3 PMID:16475804 -1.8.3.1 sulfite arabidopsis thaliana 4500.0 4500.0 1 PMID:16407262 -1.8.3.1 sulfite gallus gallus 73.0 54.55 2 PMID:22263579 -1.8.3.1 sulfite homo sapiens 32.4 25.0 41 PMID:14729666;PMID:16229463;PMID:16475804;PMID:22263579;PMID:22975842;PMID:23779234;PMID:25314640 -1.8.3.1 sulfite thermus thermophilus 53.32 26.86 2 PMID:16830073 -1.8.3.2 2-mercaptoethanol aspergillus oryzae 55400.0 27750.0 2 PMID:20727152;PMID:21327412 -1.8.3.2 2-mercaptoethanol gallus gallus 20.3 20.3 1 PMID:8940019 -1.8.3.2 5,5'-dithiobis(2-nitrobenzoic acid) autographa californica nucleopolyhedrovirus 1.275 1.275 1 PMID:28904203 -1.8.3.2 d-cys aspergillus oryzae 78600.0 42275.0 2 PMID:20727152;PMID:21327412 -1.8.3.2 dithiothreitol aspergillus oryzae 337800.0 323400.0 2 PMID:20727152;PMID:21327412 -1.8.3.2 dithiothreitol gallus gallus 17.2 17.2 1 PMID:8940019 -1.8.3.2 dithiothreitol glycine max 13.9 13.9 1 PMID:25265152 -1.8.3.2 dithiothreitol homo sapiens 1.1 1.1 1 PMID:15683237 -1.8.3.2 dithiothreitol saccharomyces cerevisiae 3.43 3.43 1 PMID:17298084 -1.8.3.2 dithiothreitol trypanosoma brucei 45.1 45.05 2 PMID:20121244;PMID:24379406 -1.8.3.2 dtt gallus gallus 1013.0 20.0 3 PMID:12176051;PMID:12693953 -1.8.3.2 dtt saccharomyces cerevisiae 4.0 4.0 1 PMID:12176051 -1.8.3.2 glutathione aspergillus niger 66.67 66.67 1 PMID:12176051 -1.8.3.2 glutathione aspergillus oryzae 3600000.0 1848750.0 2 PMID:20727152;PMID:21327412 -1.8.3.2 glutathione saccharomyces cerevisiae 0.00083 0.00083 1 PMID:28298220 -1.8.3.2 gsh gallus gallus 23.1 23.1 1 PMID:8940019 -1.8.3.2 l-cys aspergillus oryzae 52300.0 29550.0 2 PMID:20727152;PMID:21327412 -1.8.3.2 l-cys gallus gallus 21.3 21.3 1 PMID:8940019 -1.8.3.2 o2 saccharomyces cerevisiae 1.3 1.2000000000000002 2 PMID:19679655 -1.8.3.2 rnase a aspergillus niger 0.002 0.002 1 PMID:12176051 -1.8.3.2 rnase a glycine max 17.5 17.5 1 PMID:25265152 -1.8.3.2 rnase a trypanosoma brucei 21.9 21.9 1 PMID:24379406 -1.8.3.2 rrnasea trypanosoma brucei 22.0 22.0 1 PMID:20121244 -1.8.3.3 2-mercaptoethanol aspergillus oryzae 100.0 100.0 1 PMID:20727152 -1.8.3.3 cytochrome c homo sapiens 4.5 4.5 1 PMID:15683237 -1.8.3.3 d-cys aspergillus oryzae 5950.0 5950.0 1 PMID:20727152 -1.8.3.3 dithiothreitol aspergillus oryzae 309000.0 309000.0 1 PMID:20727152 -1.8.3.3 dithiothreitol homo sapiens 1.1 1.1 1 PMID:15683237 -1.8.3.3 glutathione aspergillus oryzae 3600000.0 3600000.0 1 PMID:20727152 -1.8.3.3 l-cys aspergillus oryzae 52300.0 52300.0 1 PMID:20727152 -1.8.3.5 farnesyl-l-cysteine homo sapiens 0.000133 0.000133 1 PMID:12186880 -1.8.3.7 abz-attplcgpsrasilsgr thermomonospora curvata 0.0233 0.0233 1 PMID:31588272 -1.8.3.7 abz-sal-3-oxo-l-ala-sptra-nh2 thermomonospora curvata 0.027 0.027 1 PMID:28605111 -1.8.3.7 abz-salcsptra-nh2 thermomonospora curvata 0.027 0.027 2 PMID:26403223;PMID:27862795 -1.8.4.1 cysteine aspergillus flavipes 0.056 0.056 1 * -1.8.4.1 glutathione aspergillus flavipes 0.078 0.078 1 * -1.8.4.10 3'-phosphoadenosine-5'-phosphosulfate physcomitrium patens 0.0002 0.0002 1 PMID:24100135 -1.8.4.10 5'-adenylyl sulfate mycobacterium tuberculosis 0.13 0.08 3 PMID:23711725 -1.8.4.10 5'-adenylyl sulfate physcomitrium patens 0.333 0.333 1 PMID:24100135 -1.8.4.10 adenosine-5'-phosphosulfate catharanthus roseus 3.4 2.75 2 PMID:10082930 -1.8.4.11 9-fluorenylmethyl chloroformate-labeled l-methionine-(s)-s-oxide arabidopsis thaliana 1.59 1.25 2 * -1.8.4.11 dabsyl l-methionine-(s)-sulfoxide caenorhabditis elegans 0.06 0.06 1 PMID:15639227 -1.8.4.11 dabsyl-l-methionine (s)-s-oxide treponema denticola 0.12 0.073 2 PMID:27551953 -1.8.4.11 dabsyl-l-methionine (s)-sulfoxide helicobacter pylori 0.17 0.17 1 PMID:33807684 -1.8.4.11 dabsyl-l-methionine-(s)-s-oxide mus musculus 0.78 0.53 2 PMID:15924425 -1.8.4.11 dabsylated l-methionine (s)-sulfoxide clostridium sp. 84.0 84.0 1 PMID:18767149 -1.8.4.11 dithiothreitol alkaliphilus oremlandii 10.0 10.0 1 PMID:25600814 -1.8.4.11 glutaredoxin 2 alkaliphilus oremlandii 4.5 4.5 1 PMID:25600814 -1.8.4.11 l-methionine (s)-sulfoxide escherichia coli 3.7 3.7 1 PMID:15680231 -1.8.4.11 l-methionine (s)-sulfoxide neisseria meningitidis 7.0 3.8 2 PMID:12954610 -1.8.4.11 l-methionine (s)-sulfoxide trypanosoma cruzi 0.52 0.42000000000000004 2 PMID:20969952 -1.8.4.11 l-methionine (s,r)-sulfoxide neisseria meningitidis 3.7 3.7 1 PMID:11812798 -1.8.4.11 l-methionine-(s)-s-oxide leptospira interrogans 0.39 0.244 2 PMID:33242654 -1.8.4.11 l-methionine-(s)-s-oxide trypanosoma cruzi 0.23 0.23 1 PMID:32682073 -1.8.4.11 n-acetyl-l-methionine-(s)-s-oxide leptospira interrogans 0.415 0.309 2 PMID:33242654 -1.8.4.11 n-acetyl-l-methionine-(s)-s-oxide trypanosoma cruzi 0.22 0.22 1 PMID:32682073 -1.8.4.11 thioredoxin leptospira interrogans 0.508 0.211 4 PMID:33242654 -1.8.4.11 thioredoxin nicotiana tabacum 0.048 0.048 1 PMID:23552991 -1.8.4.11 thioredoxin solanum lycopersicum 0.15 0.13 2 PMID:22447340 -1.8.4.11 thioredoxin trypanosoma cruzi 0.025 0.025 1 PMID:32682073 -1.8.4.11 tryparedoxin i trypanosoma cruzi 0.52 0.467 3 PMID:20969952;PMID:32682073 -1.8.4.12 (s)-1-nonen-4-ol neisseria meningitidis 1.1 1.1 1 PMID:15680231 -1.8.4.12 cdsp32 arabidopsis sp. 0.035 0.035 1 PMID:17761174 -1.8.4.12 dabsyl-l-methionine (r)-s-oxide treponema denticola 0.116 0.060000000000000005 2 PMID:27551953 -1.8.4.12 dabsyl-l-methionine (r)-sulfoxide arabidopsis thaliana 0.075 0.021 4 PMID:19457862 -1.8.4.12 dabsyl-l-methionine (r)-sulfoxide helicobacter pylori 0.157 0.157 1 PMID:33807684 -1.8.4.12 dithiothreitol solanum lycopersicum 0.09 0.09 1 PMID:23283574 -1.8.4.12 glutaredoxin leptospira interrogans 0.0145 0.0145 1 PMID:33242654 -1.8.4.12 glutaredoxin c4 arabidopsis thaliana 0.48 0.25 2 PMID:19457862 -1.8.4.12 glutaredoxin s12 arabidopsis sp. 0.17 0.17 1 PMID:17761174 -1.8.4.12 glutaredoxin s12 arabidopsis thaliana 0.58 0.305 2 PMID:19457862 -1.8.4.12 l-methionine (r)-sulfoxide escherichia coli 0.01 0.01 1 PMID:11677230 -1.8.4.12 l-methionine (r)-sulfoxide glycine max 2.86 1.4949999999999999 2 PMID:23776515 -1.8.4.12 l-methionine (r,s)-sulfoxide neisseria meningitidis 2.8 2.8 1 PMID:11812798 -1.8.4.12 l-methionine-(r)-s-oxide arabidopsis thaliana 0.07 0.045000000000000005 2 PMID:15923321 -1.8.4.12 l-methionine-(r)-s-oxide homo sapiens 0.83 0.83 1 * -1.8.4.12 l-methionine-(r)-s-oxide leptospira interrogans 0.0076 0.0076 1 PMID:33242654 -1.8.4.12 l-methionine-(r)-s-oxide mus musculus 0.46 0.22 3 * -1.8.4.12 l-methionine-(r)-s-oxide trypanosoma cruzi 0.002 0.002 1 PMID:32682073 -1.8.4.12 n-acetyl-l-methionine (r)-sulfoxide glycine max 2.04 1.1400000000000001 2 PMID:23776515 -1.8.4.12 n-acetyl-l-methionine-(r)-s-oxide leptospira interrogans 0.014 0.014 1 PMID:33242654 -1.8.4.12 n-acetyl-l-methionine-(r)-s-oxide trypanosoma cruzi 0.0048 0.0048 1 PMID:32682073 -1.8.4.12 thioredoxin leptospira interrogans 0.0043 0.0043 1 PMID:33242654 -1.8.4.12 thioredoxin nicotiana tabacum 3.2e-06 3.2e-06 1 PMID:24114470 -1.8.4.12 thioredoxin trypanosoma cruzi 0.0056 0.0056 1 PMID:32682073 -1.8.4.12 thioredoxin h1 arabidopsis thaliana 1.28 1.28 1 PMID:19457862 -1.8.4.12 tryparedoxin i trypanosoma cruzi 0.00583 0.00583 1 PMID:32682073 -1.8.4.14 l-methionine (r)-s-oxide escherichia coli 6.9 6.9 1 PMID:17535911 -1.8.4.14 l-methionine (r)-s-oxide neisseria meningitidis 14.0 14.0 1 PMID:20489204 -1.8.4.14 l-methionine (r)-s-oxide thermoplasma acidophilum 2.8 2.8 1 PMID:25043974 -1.8.4.2 2-mercaptoethanol glutathione disulfide chlamydomonas reinhardtii 161.6 30.4 3 PMID:18216016;PMID:20406640 -1.8.4.2 2-mercaptoethanol glutathione disulfide populus sp. 23.0 23.0 1 PMID:21707412 -1.8.4.2 glutathione chlamydomonas reinhardtii 161.0 93.75 2 PMID:20406640 -1.8.4.2 glutathione populus sp. 92.8 92.8 1 PMID:21707412 -1.8.4.2 glutathionylated bsa populus sp. 31.0 31.0 1 PMID:21707412 -1.8.4.8 3'-phosphoadenylyl sulfate bacillus subtilis 0.335 0.242 2 PMID:14627706 -1.8.4.8 3'-phosphoadenylyl-sulfate bacillus subtilis 0.382 0.277 2 PMID:14627706 -1.8.4.8 3'-phosphoadenylyl-sulfate escherichia coli 3.5 3.5 1 PMID:10075658 -1.8.4.8 glutaredoxin 1 bacillus subtilis 0.421 0.2835 2 PMID:14627706 -1.8.4.8 thioredoxin 1 bacillus subtilis 0.219 0.1965 2 PMID:14627706 -1.8.4.9 3'-phosphoadenosine 5'-phosphosulfate physcomitrium patens 0.00075 0.00075 1 PMID:17519237 -1.8.4.9 3'-phosphoadenosine-5'-phosphosulfate mycobacterium tuberculosis 0.012 0.012 1 PMID:16981690 -1.8.4.9 5'-adenylyl sulfate glycine max 11.3 9.850000000000001 2 PMID:17761201 -1.8.4.9 5'-adenylylsulfate catharanthus roseus 3.4 2.75 2 PMID:10082930 -1.8.4.9 5'-adenylylsulfate lemna minor 56.0 56.0 1 PMID:10625629 -1.8.4.9 5'-adenylylsulfate mycobacterium tuberculosis 0.153 0.153 1 PMID:16981690 -1.8.4.9 adenosine 5'-phosphosulfate physcomitrium patens 0.176 0.176 1 PMID:17519237 -1.8.4.9 dithiothreitol glycine max 10.1 10.1 1 PMID:17761201 -1.8.4.9 glutathione glycine max 8.4 8.4 1 PMID:17761201 -1.8.5.1 dehydroascorbate actinidia chinensis 2e-05 2e-05 2 PMID:32107543 -1.8.5.1 dehydroascorbate chlamydomonas reinhardtii 400.43 1.67 4 PMID:18216016;PMID:20406640;PMID:29028546 -1.8.5.1 dehydroascorbate homo sapiens 5.27 2.6405 2 PMID:22522127;PMID:8660320 -1.8.5.1 dehydroascorbate ipomoea batatas 368.2 184.10002 2 PMID:18444663;PMID:32107543 -1.8.5.1 dehydroascorbate liriodendron chinense 3e-06 3e-06 1 PMID:32107543 -1.8.5.1 dehydroascorbate nilaparvata lugens 0.21 0.21 1 PMID:31328816 -1.8.5.1 dehydroascorbate pinus bungeana 10.15 5.075005 2 PMID:19903221;PMID:32107543 -1.8.5.1 dehydroascorbate populus tomentosa 21150.0 6565.01055 6 PMID:23661023;PMID:32107543 -1.8.5.1 dehydroascorbate populus trichocarpa 0.00047 0.00046 4 PMID:32107543 -1.8.5.1 dehydroascorbate spinacia oleracea 490.0 350.0 2 PMID:12603325 -1.8.5.1 dehydroascorbate taiwanofungus camphoratus 21.51 21.51 1 PMID:19886686 -1.8.5.1 glutathione actinidia chinensis 3e-05 3e-05 2 PMID:32107543 -1.8.5.1 glutathione chlamydomonas reinhardtii 390.06 1.82 3 PMID:20406640;PMID:29028546 -1.8.5.1 glutathione homo sapiens 0.0175 0.0175 1 PMID:22522127 -1.8.5.1 glutathione ipomoea batatas 100.6 50.30005 2 PMID:18444663;PMID:32107543 -1.8.5.1 glutathione liriodendron chinense 1e-06 1e-06 1 PMID:32107543 -1.8.5.1 glutathione pinus bungeana 40.53 20.26502 2 PMID:19903221;PMID:32107543 -1.8.5.1 glutathione populus tomentosa 99830.0 20425.0499 6 PMID:23661023;PMID:32107543 -1.8.5.1 gsh spinacia oleracea 490.0 490.0 1 PMID:12603325 -1.8.5.2 thiosulfate acidianus ambivalens 167.0 167.0 1 PMID:15306018 -1.8.5.3 2-carboxypyridine n-oxide escherichia coli 8.0 8.0 1 PMID:8969520 -1.8.5.3 2-chloropyridine n-oxide escherichia coli 307.0 307.0 1 PMID:8969520 -1.8.5.3 2-hydroxymethylpyridine n-oxide escherichia coli 89.3 89.3 1 PMID:8969520 -1.8.5.3 2-mercaptopyridine n-oxide escherichia coli 8.0 8.0 1 PMID:8969520 -1.8.5.3 2-methylpyridine n-oxide escherichia coli 247.0 247.0 1 PMID:8969520 -1.8.5.3 3-amidopyridine n-oxide escherichia coli 237.0 237.0 1 PMID:8969520 -1.8.5.3 3-carboxypyridine n-oxide escherichia coli 168.0 168.0 1 PMID:8969520 -1.8.5.3 3-hydroxymethylpyridine n-oxide escherichia coli 214.0 214.0 1 PMID:8969520 -1.8.5.3 3-hydroxypyridine n-oxide escherichia coli 429.0 429.0 1 PMID:8969520 -1.8.5.3 3-methylpyridine n-oxide escherichia coli 231.0 231.0 1 PMID:8969520 -1.8.5.3 3alpha-hydroxybenzylpyridine n-oxide escherichia coli 229.0 229.0 1 PMID:8969520 -1.8.5.3 4-carboxypyridine n-oxide escherichia coli 30.3 30.3 1 PMID:8969520 -1.8.5.3 4-chloropyridine n-oxide escherichia coli 212.0 212.0 1 PMID:8969520 -1.8.5.3 4-hydroxymethylpyridine n-oxide escherichia coli 226.0 226.0 1 PMID:8969520 -1.8.5.3 4-methylmorpholine n-oxide escherichia coli 573.0 573.0 1 PMID:8969520 -1.8.5.3 4-methylpyridine n-oxide escherichia coli 268.0 268.0 1 PMID:8969520 -1.8.5.3 4-phenylpyridine n-oxide escherichia coli 297.0 297.0 1 PMID:8969520 -1.8.5.3 adenosine-1n-oxide cereibacter sphaeroides 110.0 110.0 1 PMID:11278798 -1.8.5.3 dimethyl sulfoxide rhodobacter capsulatus 470.0 245.5 2 PMID:10835270 -1.8.5.3 dimethyldodecylamine n-oxide escherichia coli 239.0 239.0 1 PMID:8969520 -1.8.5.3 dimethylsulfide rhodobacter capsulatus 8.0 8.0 1 PMID:10387097 -1.8.5.3 dimethylsulfoxide cereibacter sphaeroides 1120.0 585.0 2 PMID:11278798;PMID:29299674 -1.8.5.3 dimethylsulfoxide escherichia coli 79.9 79.9 1 PMID:8969520 -1.8.5.3 dimethylsulfoxide rhodobacter capsulatus 42.9 42.9 1 PMID:15063748 -1.8.5.3 dithane 1-oxide escherichia coli 28.4 28.4 1 PMID:8969520 -1.8.5.3 dl-methyl phenyl sulfoxide escherichia coli 99.6 99.6 1 PMID:8969520 -1.8.5.3 methionine sulfoxide cereibacter sphaeroides 58.0 58.0 1 PMID:11278798 -1.8.5.3 methionine sulfoxide escherichia coli 61.1 61.1 1 PMID:8969520 -1.8.5.3 pyridine n-oxide escherichia coli 243.0 221.5 2 PMID:8969520;PMID:9492325 -1.8.5.3 reduced benzyl viologen escherichia coli 61.0 61.0 1 PMID:9492325 -1.8.5.3 reduced benzyl viologen rhodobacter capsulatus 17.0 17.0 1 PMID:10387097 -1.8.5.3 reduced methyl viologen rhodobacter capsulatus 27.0 27.0 1 PMID:10387097 -1.8.5.3 tetramethylene sulfoxide escherichia coli 119.0 119.0 1 PMID:8969520 -1.8.5.3 trimethylamine n-oxide cereibacter sphaeroides 2300.0 2300.0 1 PMID:11278798 -1.8.5.3 trimethylamine n-oxide escherichia coli 1203.0 1203.0 1 PMID:8969520 -1.8.5.3 trimethylamine-n-oxide rhodobacter capsulatus 134.5 134.5 1 PMID:15063748 -1.8.5.4 2,3-dimethyl-1,4-naphthoquinone acidianus ambivalens 0.1 0.1 1 PMID:19438211 -1.8.5.4 caldariella quinone acidianus ambivalens 0.43 0.43 1 PMID:19438211 -1.8.5.4 coenzyme q homo sapiens 364.0 362.0 2 PMID:25725526 -1.8.5.4 cyanide homo sapiens 330.0 330.0 2 PMID:22852582;PMID:25725526 -1.8.5.4 cysteine homo sapiens 94.0 94.0 1 PMID:25225291 -1.8.5.4 decylubiquinone acidianus ambivalens 0.38 0.38 1 PMID:19438211 -1.8.5.4 decylubiquinone caldivirga maquilingensis 0.6 0.6 1 PMID:23103448 -1.8.5.4 duroquinone thiocapsa roseopersicina 1.64 1.64 1 PMID:33202220 -1.8.5.4 homocysteine homo sapiens 92.0 92.0 1 PMID:25225291 -1.8.5.4 menadione acidianus ambivalens 0.15 0.15 1 PMID:19438211 -1.8.5.4 na2s thiocapsa roseopersicina 1.64 1.64 1 PMID:33202220 -1.8.5.4 reduced glutathione homo sapiens 113.0 113.0 1 PMID:25225291 -1.8.5.4 sulfide acidithiobacillus ferrooxidans 6.5 6.5 1 PMID:2530790 -1.8.5.4 sulfide caldivirga maquilingensis 0.6 0.6 1 PMID:23103448 -1.8.5.4 sulfide chlorobaculum tepidum 54.0 54.0 1 PMID:27190141 -1.8.5.4 sulfide homo sapiens 379.0 79.0 10 PMID:22852582;PMID:25225291;PMID:25725526;PMID:28512131 -1.8.5.4 sulfite homo sapiens 368.0 368.0 2 PMID:22852582;PMID:25725526 -1.8.5.4 ubiquinone-1 homo sapiens 364.0 362.0 2 PMID:22852582 -1.8.5.6 sulfite aquifex aeolicus 567.0 309.95 2 PMID:32735861 -1.8.5.7 (glutathione-s-yl)-2-chloro-1,4-benzoquinone populus trichocarpa 7.96 7.96 1 * -1.8.5.7 2-(glutathione-s-yl)-1,4-benzoquinone populus trichocarpa 1.62 1.62 1 * -1.8.5.7 2-(glutathione-s-yl)-hydroquinone cupriavidus necator 22.0 22.0 1 * -1.8.5.7 2-(glutathione-s-yl)-hydroquinone escherichia coli 14.0 14.0 1 * -1.8.5.7 2-(glutathione-s-yl)-hydroquinone saccharomyces cerevisiae 13.0 13.0 1 * -1.8.5.7 2-(glutathione-s-yl)-hydroquinone sphingobium chlorophenolicum 11.0 11.0 1 * -1.8.5.7 2-(glutathione-s-yl)-hydroxy-p-hydroquinone cupriavidus necator 4.4 4.4 1 * -1.8.5.7 2-(glutathione-s-yl)-hydroxy-p-hydroquinone escherichia coli 7.2 7.2 1 * -1.8.5.7 2-(glutathione-s-yl)-hydroxy-p-hydroquinone saccharomyces cerevisiae 7.1 7.1 1 * -1.8.5.7 2-(glutathione-s-yl)-hydroxy-p-hydroquinone sphingobium chlorophenolicum 19.0 19.0 1 * -1.8.5.7 2-(glutathione-s-yl)-menadiol cupriavidus necator 13.0 13.0 1 * -1.8.5.7 2-(glutathione-s-yl)-menadiol escherichia coli 4.9 4.9 1 * -1.8.5.7 2-(glutathione-s-yl)-menadiol populus trichocarpa 9.42 9.42 1 * -1.8.5.7 2-(glutathione-s-yl)-menadiol saccharomyces cerevisiae 14.0 14.0 1 * -1.8.5.7 2-(glutathione-s-yl)-menadiol sphingobium chlorophenolicum 4.6 4.6 1 * -1.8.5.7 2-(glutathione-s-yl)-menadione populus trichocarpa 4.75 4.75 1 * -1.8.5.7 2-(glutathione-s-yl)-methyl-p-hydroquinone cupriavidus necator 31.0 31.0 1 * -1.8.5.7 2-(glutathione-s-yl)-methyl-p-hydroquinone escherichia coli 15.0 15.0 1 * -1.8.5.7 2-(glutathione-s-yl)-methyl-p-hydroquinone saccharomyces cerevisiae 8.4 8.4 1 * -1.8.5.7 2-(glutathione-s-yl)-methyl-p-hydroquinone sphingobium chlorophenolicum 14.0 14.0 1 * -1.8.5.7 2-(glutathione-s-yl)-quercetin populus trichocarpa 0.013 0.013 1 * -1.8.5.7 2-mercaptoethanol sphingobium chlorophenolicum 1.09 1.09 1 PMID:20388120 -1.8.5.7 dithiothreitol sphingobium chlorophenolicum 0.89 0.89 1 PMID:20388120 -1.8.5.7 glutathione cupriavidus necator 37.0 37.0 1 * -1.8.5.7 glutathione escherichia coli 15.0 15.0 1 * -1.8.5.7 glutathione saccharomyces cerevisiae 7.5 7.5 1 * -1.8.5.7 glutathione sphingobium chlorophenolicum 14.0 8.04 2 PMID:20388120 -1.8.5.7 l-cysteine sphingobium chlorophenolicum 0.37 0.37 1 PMID:20388120 -1.8.5.8 glutathione homo sapiens 128.0 108.5 2 PMID:28512131 -1.8.5.8 sulfide homo sapiens 373.0 92.0 7 PMID:25225291;PMID:28512131 -1.8.5.8 sulfite homo sapiens 650.0 516.0 2 PMID:28512131 -1.8.5.9 ubiquinone-1 escherichia coli 7e-06 7e-06 1 PMID:16027117 -1.8.7.1 nitrite cyanidioschyzon merolae 243.0 243.0 1 PMID:19622064 -1.8.7.1 reduced ferredoxin brassica rapa 6.0 4.8 2 PMID:9339549 -1.8.7.1 reduced ferredoxin zea mays 3.65 3.65 1 PMID:16469743 -1.8.7.1 sulfite brassica rapa 9.1 5.75 2 PMID:9339549 -1.8.7.1 sulfite cyanidioschyzon merolae 4.7 1.93 3 PMID:19622064;PMID:28057796 -1.8.98.1 dihydromethanophenazine methanosarcina thermophila 74.0 74.0 1 PMID:11034998 -1.8.98.2 atp saccharomyces cerevisiae 0.03 0.03 1 PMID:21237158 -1.8.98.2 gamma-s-atp saccharomyces cerevisiae 0.016 0.016 1 PMID:21237158 -1.8.98.2 peroxiredoxin-(s-hydroxy-s-oxocysteine) arabidopsis thaliana 0.011 0.00571 2 PMID:20176891 -1.8.98.2 peroxiredoxin-(s-hydroxy-s-oxocysteine) homo sapiens 0.003 0.003 1 PMID:16565085 -1.8.98.8 a reduced factor 420 methanococcus aeolicus 3.4 3.4 1 PMID:37403630 -1.8.98.8 a reduced factor 420 methanococcus voltae 2.4 2.4 1 PMID:37403630 -1.8.98.8 nadph methanococcus aeolicus 0.014 0.014 1 PMID:37403630 -1.8.98.8 nadph methanococcus voltae 0.029 0.029 1 PMID:37403630 -1.9.6.1 nitrate campylobacter jejuni 5.91 5.91 1 PMID:29931366 -1.9.6.1 nitrate cereibacter sphaeroides f. sp. denitrificans 61.0 61.0 1 PMID:30707885 -1.97.1.1 bromate azospira oryzae 0.508 0.508 1 PMID:30968916 -1.97.1.1 chlorate azospira oryzae 0.452 0.452 1 PMID:30968916 -1.97.1.1 chlorate haloferax mediterranei 46.0 46.0 1 PMID:25512066 -1.97.1.1 iodate azospira oryzae 0.598 0.598 1 PMID:30968916 -1.97.1.1 perchlorate azospira oryzae 0.452 0.452 1 PMID:30968916 -1.97.1.14 selenate enterobacter cloacae 5.0 5.0 1 PMID:16885262 -1.97.1.9 selenate enterobacter cloacae 5.0 5.0 1 PMID:18449586 -1.97.1.9 selenate thauera selenatis 387.0 387.0 1 PMID:9295321 -2.1.1.1 2-methoxypyridine homo sapiens 0.002 0.002 1 PMID:27570878 -2.1.1.1 2-methylpyridine homo sapiens 0.01 0.01 1 PMID:27570878 -2.1.1.1 3-acetylpyridine homo sapiens 0.014 0.014 1 PMID:27570878 -2.1.1.1 4-methylnicotinamide homo sapiens 0.091 0.091 1 PMID:27570878 -2.1.1.1 4-phenylpyridine homo sapiens 9.3e-05 9.3e-05 1 PMID:29549048 -2.1.1.1 isoquinoline homo sapiens 0.017 0.017 1 PMID:27570878 -2.1.1.1 nicotinamide homo sapiens 1.02 0.0895 4 PMID:21823666;PMID:23435346;PMID:27570878;PMID:30148963 -2.1.1.1 nicotinimidamide homo sapiens 0.014 0.014 1 PMID:27570878 -2.1.1.1 norharman homo sapiens 0.0004 0.0004 1 PMID:27389312 -2.1.1.1 quinoline homo sapiens 0.046 0.028499999999999998 2 PMID:27570878;PMID:30148963 -2.1.1.1 quinoline 3-carboxamide homo sapiens 0.007 0.007 1 PMID:27570878 -2.1.1.1 s-adenosyl-l-methionine homo sapiens 0.068 0.038000000000000006 2 PMID:29320176;PMID:30148963 -2.1.1.1 tetrahydroisoquinoline homo sapiens 0.045 0.045 1 PMID:27570878 -2.1.1.1 thionicotinamide homo sapiens 0.033 0.033 1 PMID:27570878 -2.1.1.10 dl-homocysteine brassica oleracea 0.0375 0.0375 1 PMID:17391716 -2.1.1.10 l-homocysteine escherichia coli 0.38 0.38 1 PMID:10026151 -2.1.1.100 biotin-s-farnesyl-l-cysteine anopheles gambiae 0.93 0.93 1 PMID:25059662 -2.1.1.100 s-adenosyl-l-methionine anopheles gambiae 0.5 0.5 1 PMID:25059662 -2.1.1.100 s-adenosyl-l-methionine homo sapiens 1.25 1.25 1 PMID:25059662 -2.1.1.103 ethanolamine phosphate ancylostoma duodenale 117.85 117.85 1 PMID:37212658 -2.1.1.103 ethanolamine phosphate arabidopsis thaliana 0.27 0.21 3 PMID:29084845 -2.1.1.103 ethanolamine phosphate ascaris suum 3.238 3.238 1 PMID:37212658 -2.1.1.103 ethanolamine phosphate caenorhabditis elegans 0.052 0.052 1 PMID:17313371 -2.1.1.103 ethanolamine phosphate dictyocaulus viviparus 16.11 16.11 1 PMID:37212658 -2.1.1.103 ethanolamine phosphate haemonchus contortus 17.77 17.77 1 PMID:37212658 -2.1.1.103 ethanolamine phosphate oesophagostomum dentatum 5.58 5.58 1 PMID:37212658 -2.1.1.103 ethanolamine phosphate plasmodium falciparum 1.82 1.82 1 PMID:25288796 -2.1.1.103 ethanolamine phosphate toxocara canis 10.412 10.412 1 PMID:37212658 -2.1.1.103 n,n-dimethylethanolamine phosphate arabidopsis thaliana 0.27 0.22 3 PMID:29084845 -2.1.1.103 n,n-dimethylethanolamine phosphate plasmodium falciparum 3.08 3.08 1 PMID:25288796 -2.1.1.103 n-methylethanolamine phosphate arabidopsis thaliana 0.21 0.14 3 PMID:29084845 -2.1.1.103 phosphodimethylethanolamine haemonchus contortus 4.13 4.13 1 PMID:21914812 -2.1.1.103 phosphodimethylethanolamine plasmodium falciparum 3.08 3.08 1 PMID:22117061 -2.1.1.103 phosphoethanolamine haemonchus contortus 8.63 8.63 1 PMID:21914812 -2.1.1.103 phosphoethanolamine plasmodium falciparum 1.82 1.82 1 PMID:22117061 -2.1.1.103 phosphomonomethylethanolamine haemonchus contortus 4.9 4.9 1 PMID:21914812 -2.1.1.103 phosphomonomethylethanolamine plasmodium falciparum 3.63 3.63 1 PMID:22117061 -2.1.1.103 s-adenosyl-l-methionine ancylostoma duodenale 54.02 54.02 1 PMID:37212658 -2.1.1.103 s-adenosyl-l-methionine arabidopsis thaliana 0.27 0.15000000000000002 6 PMID:29084845 -2.1.1.103 s-adenosyl-l-methionine ascaris suum 144.47 144.47 1 PMID:37212658 -2.1.1.103 s-adenosyl-l-methionine caenorhabditis elegans 0.058 0.058 1 PMID:17313371 -2.1.1.103 s-adenosyl-l-methionine dictyocaulus viviparus 3.95 3.95 1 PMID:37212658 -2.1.1.103 s-adenosyl-l-methionine haemonchus contortus 71.87 5.82 3 PMID:21914812;PMID:37212658 -2.1.1.103 s-adenosyl-l-methionine oesophagostomum dentatum 45.38 45.38 1 PMID:37212658 -2.1.1.103 s-adenosyl-l-methionine plasmodium falciparum 0.49 0.44 2 PMID:22117061 -2.1.1.103 s-adenosyl-l-methionine toxocara canis 10.94 10.94 1 PMID:37212658 -2.1.1.104 3',4'-dihydroxyflavone citrus sinensis 0.0048 0.0048 1 * -2.1.1.104 3,4-dihydroxybenzoic acid ammi majus 0.013 0.013 1 PMID:15556611 -2.1.1.104 5-hydroxyferulic acid ammi majus 0.143 0.143 1 PMID:15556611 -2.1.1.104 7,8-dihydroxyflavone citrus reticulata 0.00123 0.00123 1 PMID:32182355 -2.1.1.104 7,8-dihydroxyflavone citrus sinensis 0.00313 0.00313 1 * -2.1.1.104 baicalein citrus reticulata 0.00647 0.00647 1 PMID:32182355 -2.1.1.104 baicalein citrus sinensis 0.0033 0.0033 1 * -2.1.1.104 caffeic acid ammi majus 0.068 0.068 1 PMID:15556611 -2.1.1.104 caffeic acid azadirachta indica 256.32 256.32 1 PMID:33398404 -2.1.1.104 caffeoyl-coa ammi majus 6.08 1.043 3 PMID:15556611 -2.1.1.104 caffeoyl-coa citrus sinensis 0.004 0.004 1 * -2.1.1.104 caffeoyl-coa goniophlebium amoenum 0.04 0.04 2 PMID:30685696 -2.1.1.104 caffeoyl-coa vitis vinifera 0.0082 0.0082 1 PMID:26851572 -2.1.1.104 caffeoyl-d-glucose ammi majus 6.08 0.631 3 PMID:15556611 -2.1.1.104 cyanidin 3-o-glucoside vitis vinifera 0.0129 0.0078 2 PMID:26851572 -2.1.1.104 epigallocatechin-3-o-gallate camellia sinensis 0.184 0.184 1 PMID:25644465 -2.1.1.104 eriocitrin citrus reticulata 0.00215 0.00215 1 PMID:32182355 -2.1.1.104 eriocitrin citrus sinensis 0.0027 0.0027 1 * -2.1.1.104 eriodictyol arabidopsis thaliana 0.08 0.08 1 PMID:23416302 -2.1.1.104 eriodictyol citrus reticulata 0.00488 0.00488 1 PMID:32182355 -2.1.1.104 eriodictyol citrus sinensis 0.00506 0.00506 1 * -2.1.1.104 eriodictyol goniophlebium amoenum 0.13 0.09 2 PMID:30685696 -2.1.1.104 eriodictyol mesembryanthemum crystallinum 0.1 0.1 1 PMID:25596806 -2.1.1.104 eriodictyol plagiochasma appendiculatum 0.067 0.067 1 PMID:26277769 -2.1.1.104 esculetin citrus sinensis 0.0023 0.0023 1 * -2.1.1.104 kaempferol citrus reticulata 0.00124 0.00124 1 PMID:32182355 -2.1.1.104 luteolin citrus reticulata 0.00138 0.00138 1 PMID:32182355 -2.1.1.104 luteolin citrus sinensis 0.0094 0.0094 1 * -2.1.1.104 myricetin citrus reticulata 0.00067 0.00067 1 PMID:32182355 -2.1.1.104 neoeriocitrin citrus reticulata 0.00208 0.00208 1 PMID:32182355 -2.1.1.104 neoeriocitrin citrus sinensis 0.0029 0.0029 1 * -2.1.1.104 quercetagetin ammi majus 0.071 0.071 1 PMID:15556611 -2.1.1.104 quercetagetin mesembryanthemum crystallinum 0.078 0.078 1 PMID:25596806 -2.1.1.104 quercetin ammi majus 6.08 0.938 3 PMID:15556611 -2.1.1.104 quercetin citrus reticulata 0.00096 0.00096 1 PMID:32182355 -2.1.1.104 quercetin citrus sinensis 0.0047 0.0047 1 * -2.1.1.104 quercetin goniophlebium amoenum 0.14 0.095 2 PMID:30685696 -2.1.1.104 quercetin plagiochasma appendiculatum 0.156 0.156 1 PMID:26277769 -2.1.1.104 quercetin 3-methyl ether citrus reticulata 0.00164 0.00164 1 PMID:32182355 -2.1.1.104 s-adenosyl-l-methionine azadirachta indica 44.32 44.32 1 PMID:33398404 -2.1.1.104 s-adenosyl-l-methionine camellia sinensis 0.049 0.049 1 PMID:25644465 -2.1.1.104 tricetin citrus reticulata 0.00076 0.00076 1 PMID:32182355 -2.1.1.104 tricetin vanilla planifolia 0.0913 0.05115 2 PMID:21629984 -2.1.1.106 l-tryptophan kitasatospora setae 0.233 0.233 1 PMID:33462497 -2.1.1.107 uroporphyrinogen iii pseudomonas denitrificans (nom. rej.) 38.0 38.0 1 PMID:2546914 -2.1.1.11 magnesium deuteroporphyrin rhodobacter capsulatus 0.003 0.003 1 PMID:17594291 -2.1.1.11 magnesium protoporphyrin chlorobaculum tepidum 0.14 0.14 1 PMID:18693239 -2.1.1.11 magnesium protoporphyrin rhodobacter capsulatus 0.04 0.04 1 PMID:17594291 -2.1.1.11 protoporphyrin chlorobaculum tepidum 0.0002 0.0002 1 PMID:18693239 -2.1.1.11 zinc protoporphyrin rhodobacter capsulatus 0.018 0.018 1 PMID:17594291 -2.1.1.110 sterigmatocystin aspergillus parasiticus 2.2 1.4 3 PMID:3237648;PMID:8434913 -2.1.1.117 (2,3,9,10)-tetrahydroxyberbine papaver somniferum 0.52 0.52 1 PMID:37894895 -2.1.1.117 (2,3,9,10)-tetrahydroxyberbine stephania intermedia 1.68 1.68 1 PMID:37894895 -2.1.1.117 (s)-norreticuline eschscholzia californica subsp. californica 0.01 0.01 1 PMID:28922749 -2.1.1.117 (s)-reticuline eschscholzia californica subsp. californica 0.24 0.145 2 PMID:28922749 -2.1.1.117 (s)-scoulerine eschscholzia californica subsp. californica 0.02 0.015 2 PMID:28922749 -2.1.1.117 s-adenosyl-l-methionine eschscholzia californica subsp. californica 0.12 0.01 5 PMID:28922749 -2.1.1.127 l-lys lathyrus oleraceus 6.2e-05 6.2e-05 1 PMID:12819771 -2.1.1.127 methyl-l-lys lathyrus oleraceus 0.00025 0.00025 1 PMID:12819771 -2.1.1.128 (r,s)-norlaudanosoline thalictrum flavum subsp. glaucum 0.15 0.15 1 PMID:27232113 -2.1.1.128 (s)-norcoclaurine stephania tetrandra 1.5 1.5 1 PMID:35432428 -2.1.1.13 5-methyltetrahydrofolate escherichia coli 13.0 13.0 1 * -2.1.1.13 l-homocysteine thermus thermophilus 17.7 17.7 1 PMID:37821448 -2.1.1.13 s-adenosyl-l-methionine escherichia coli 0.0367 0.029200000000000004 2 * -2.1.1.14 5-methyltetrahydropteroyl-gamma-glutamyl-gamma-glutamyl-gamma-glutamylglutamate candida albicans 0.417 0.417 1 PMID:16083849 -2.1.1.14 5-methyltetrahydropteroyl-gamma-glutamyl-gamma-glutamyl-gamma-glutamylglutamate saccharomyces cerevisiae 0.6 0.6 1 PMID:16083849 -2.1.1.14 5-methyltetrahydropteroyl-gamma-glutamyl-gamma-glutamylglutamate candida albicans 0.49 0.445 2 PMID:16083849;PMID:25545590 -2.1.1.14 5-methyltetrahydropteroyl-gamma-glutamyl-gamma-glutamylglutamate escherichia coli 0.12 0.12 1 PMID:16618097 -2.1.1.14 5-methyltetrahydropteroyl-gamma-glutamyl-gamma-glutamylglutamate saccharomyces cerevisiae 0.533 0.533 1 PMID:16083849 -2.1.1.14 5-methyltetrahydropteroyl-gamma-glutamylglutamate candida albicans 0.35 0.35 1 PMID:16083849 -2.1.1.14 5-methyltetrahydropteroyl-gamma-glutamylglutamate saccharomyces cerevisiae 0.283 0.283 1 PMID:16083849 -2.1.1.14 l-homocysteine candida albicans 0.45 0.4335 2 PMID:16083849;PMID:25545590 -2.1.1.14 l-homocysteine saccharomyces cerevisiae 0.33 0.33 1 PMID:16083849 -2.1.1.140 (rs)-coclaurine coptis japonica 0.53 0.53 1 PMID:29791083 -2.1.1.140 (s)-coclaurine coptis japonica 6.28 6.28 1 PMID:31765874 -2.1.1.140 (s)-coclaurine liriodendron chinense 0.0251 0.0251 1 PMID:36062348 -2.1.1.140 (s)-n-methylcoclaurine coptis japonica 0.00031 0.00031 1 PMID:31765874 -2.1.1.140 heliamine coptis japonica 0.6 0.6 1 PMID:29791083 -2.1.1.141 benzoate populus trichocarpa 0.003 0.003 1 PMID:23849543 -2.1.1.141 jasmonate arabidopsis thaliana 25.0 25.0 1 PMID:11287667 -2.1.1.141 jasmonate populus trichocarpa 0.013 0.013 1 PMID:23849543 -2.1.1.141 s-adenosyl-l-methionine arabidopsis thaliana 70.0 70.0 1 PMID:11287667 -2.1.1.142 24(28)-methylene lophenol glycine max 0.001 0.001 1 PMID:16271698 -2.1.1.142 24(28)-methylenelophenol glycine max 0.001 0.001 1 PMID:18007423 -2.1.1.142 24(28)methylene lophenol glycine max 0.013 0.013 1 PMID:19818974 -2.1.1.142 24,25-dehydro-27-methylene-cycloartenol glycine max 8.3e-07 8.3e-07 1 PMID:17851075 -2.1.1.142 24-fluorocycloartenol glycine max 0.0003 0.0003 1 PMID:17998159 -2.1.1.142 26,27-dehydrocycloartenol glycine max 0.00033 0.00033 1 PMID:18007423 -2.1.1.142 26,27-dehydrozymosterol arabidopsis thaliana 0.001 0.001 1 PMID:14622971 -2.1.1.142 cycloartenol arabidopsis thaliana 0.01 0.01 1 PMID:14622971;PMID:17998159 -2.1.1.142 cycloartenol glycine max 0.01 0.01 3 PMID:14622971;PMID:17851075;PMID:17998159;PMID:18007423;PMID:19818974 -2.1.1.142 cyclobranol glycine max 0.0001 0.0001 1 PMID:18590960 -2.1.1.142 lanosterol paracoccidioides brasiliensis 0.0023 0.0023 1 PMID:20624480 -2.1.1.143 24(28)-methylene lophenol glycine max 0.022 0.017499999999999998 2 PMID:19818974 -2.1.1.143 24-methylenelophenol glycine max 0.001 0.001 1 PMID:16271698 -2.1.1.146 chavicol ocimum basilicum 0.00087 0.00087 1 PMID:11884690 -2.1.1.146 eugenol ocimum basilicum 0.0031 0.0031 1 PMID:11884690 -2.1.1.146 eugenol rosa chinensis 0.019 0.019 1 PMID:16233496 -2.1.1.146 isoeugenol pimpinella anisum 0.015 0.015 1 PMID:18987218 -2.1.1.146 isoeugenol rosa chinensis 0.031 0.031 1 PMID:16233496 -2.1.1.146 t-isoeugenol ocimum basilicum 0.0013 0.0013 1 PMID:11884690 -2.1.1.148 dump helicobacter pylori 0.0072 0.0072 1 PMID:15123820 -2.1.1.15 3-hydroxydecanoic acid mycobacterium marinum 1600.0 800.2995 2 PMID:21926202;PMID:26526103 -2.1.1.15 3-hydroxydodecanoic acid mycobacterium marinum 1346.0 1346.0 1 PMID:21926202 -2.1.1.15 3-hydroxyoctanoic acid mycobacterium marinum 358.0 179.244 2 PMID:21926202;PMID:26526103 -2.1.1.15 decanoic acid mycobacterium marinum 489.0 244.622 2 PMID:21926202;PMID:26526103 -2.1.1.15 dodecanoic acid mycobacterium marinum 1165.0 1165.0 1 PMID:21926202 -2.1.1.15 octanoic acid mycobacterium marinum 510.0 255.2305 2 PMID:21926202;PMID:26526103 -2.1.1.15 s-adenosyl-l-methionine mycobacterium marinum 0.598 0.598 1 PMID:26526103 -2.1.1.150 6-hydroxydaidzein glycine max 1.0 1.0 1 PMID:32894761 -2.1.1.154 isoliquiritigenin medicago truncatula 0.15 0.135 2 PMID:38571285 -2.1.1.157 n,n-dimethylglycine galdieria sulphuraria 1.4 1.4 1 PMID:18623062 -2.1.1.157 n,n-dimethylglycine methanohalophilus portucalensis 2.68 2.68 1 PMID:19693490 -2.1.1.157 sarcosine galdieria sulphuraria 1.07 1.07 1 PMID:18623062 -2.1.1.157 sarcosine methanohalophilus portucalensis 0.44 0.44 1 PMID:19693490 -2.1.1.164 dechlorinated 4'-demethyl-rebeccamycin lentzea aerocolonigenes 0.047 0.047 1 PMID:16575939 -2.1.1.164 s-adenosyl-l-methionine lentzea aerocolonigenes 0.047 0.047 2 PMID:16575939;PMID:18502766 -2.1.1.166 s-adenosyl-l-methionine escherichia coli 0.001 0.001 1 PMID:12181314 -2.1.1.176 cytosine967 in 16s rrna escherichia coli 0.012 0.012 1 PMID:10194318 -2.1.1.177 pseudouridine1915 in 23s rrna escherichia coli 0.04 0.04 1 PMID:28428565 -2.1.1.184 adenine2085 in 23s rrna bacillus subtilis 0.64 0.323185 2 PMID:12907737;PMID:12946350 -2.1.1.184 s-adenosyl-l-methionine bacillus subtilis 0.066 0.06575 2 PMID:12907737;PMID:12946350 -2.1.1.190 s-adenosyl-l-methionine escherichia coli 0.06 0.06 1 PMID:11779873 -2.1.1.190 uracil1939 in 23s rrna escherichia coli 0.18 0.06 3 PMID:11779873;PMID:15766524 -2.1.1.193 s-adenosyl-l-methionine escherichia coli 0.0007 0.0007 1 PMID:17872509 -2.1.1.193 uracil1498 in 16s rrna escherichia coli 0.0013 0.0013 1 PMID:17872509 -2.1.1.197 malonyl-[acyl-carrier protein] bacillus cereus 225.0 225.0 1 PMID:22965231 -2.1.1.197 s-adenosyl-l-methionine bacillus cereus 173.0 173.0 1 PMID:22965231 -2.1.1.2 guanidinoacetate rattus norvegicus 0.081 0.0799 2 PMID:8119887 -2.1.1.2 s-adenosyl-l-methionine rattus norvegicus 3.8 3.8 1 PMID:15533043 -2.1.1.20 gly homo sapiens 1.6 1.6 1 PMID:14651980 -2.1.1.20 gly rattus norvegicus 0.45 0.45 1 PMID:12859184 -2.1.1.20 glycine rattus norvegicus 51.9 0.7 3 PMID:18501206;PMID:37870315 -2.1.1.20 s-adenosyl-l-methionine homo sapiens 1.6 1.6 1 PMID:14651980 -2.1.1.20 s-adenosyl-l-methionine rattus norvegicus 2.908 1.679 2 PMID:12859184;PMID:27355841 -2.1.1.200 nucleoside32 in ectrnafmet1(cau) escherichia coli 0.0253 0.0253 1 PMID:26202969 -2.1.1.200 nucleoside32 in ectrnafmet2(cau) escherichia coli 0.0237 0.0237 1 PMID:26202969 -2.1.1.200 nucleoside32 in ectrnagln1(uug) escherichia coli 0.02 0.02 1 PMID:26202969 -2.1.1.200 nucleoside32 in ectrnagln2(cug) escherichia coli 0.0235 0.0235 1 PMID:26202969 -2.1.1.200 nucleoside32 in ectrnaser1(uga) escherichia coli 0.0383 0.0383 1 PMID:26202969 -2.1.1.200 nucleoside32 in ectrnatrp1(cca) escherichia coli 0.0218 0.0218 1 PMID:26202969 -2.1.1.204 cytosine38 in trnagly(ghcc) homo sapiens 0.268 0.268 1 PMID:34110975 -2.1.1.21 l-glutamate pseudomonas sp. 0.347 0.174915 2 PMID:1126928 -2.1.1.218 adenine9 in trnaphe thermococcus kodakarensis 0.0093 0.0093 1 PMID:30704107 -2.1.1.218 adenine9 in trnathr thermococcus kodakarensis 0.002 0.002 1 PMID:30704107 -2.1.1.22 carnosine gallus gallus 0.008 0.0055 2 PMID:23705015;PMID:26001783 -2.1.1.22 carnosine homo sapiens 0.002 0.002 1 PMID:26001783 -2.1.1.22 carnosine rattus norvegicus 0.003 0.003 1 PMID:26001783 -2.1.1.22 s-adenosyl-l-methionine gallus gallus 0.042 0.026500000000000003 2 PMID:23705015;PMID:26001783 -2.1.1.22 s-adenosyl-l-methionine homo sapiens 0.06 0.06 1 PMID:26001783 -2.1.1.22 s-adenosyl-l-methionine rattus norvegicus 0.078 0.078 1 PMID:26001783 -2.1.1.221 guanine9 in trnaarg thermococcus kodakarensis 0.0002 0.0002 1 PMID:30704107 -2.1.1.221 guanine9 in trnagly saccharomyces cerevisiae 0.0028 0.0028 1 PMID:24081582 -2.1.1.221 guanine9 in trnagly schizosaccharomyces pombe 0.0027 0.0027 1 PMID:24081582 -2.1.1.221 guanine9 in trnagly thermococcus kodakarensis 0.0025 0.0025 1 PMID:30704107 -2.1.1.221 guanine9 in trnaglygcc homo sapiens 0.0023 0.0023 1 PMID:23793893 -2.1.1.221 guanine9 in trnaglygcc saccharomyces cerevisiae 0.009 0.009 1 PMID:23793893 -2.1.1.221 guanine9 in trnaphe thermococcus kodakarensis 0.0232 0.0232 1 PMID:30704107 -2.1.1.221 guanine9 in trnavaluac homo sapiens 0.012 0.012 1 PMID:23793893 -2.1.1.221 guanine9 in trnavaluac saccharomyces cerevisiae 0.0052 0.0052 1 PMID:23793893 -2.1.1.224 2-methyladenine2503 in 23s rrna fragment (2447-2625) staphylococcus aureus 0.000575 0.000575 1 PMID:35015630 -2.1.1.225 adenosine4 in trnahis saccharomyces cerevisiae 0.004 0.004 1 PMID:17242307 -2.1.1.228 guanine37 in escherichia coli trnapro escherichia coli 0.017 0.017 1 PMID:17868690 -2.1.1.228 guanine37 in methanocaldococcus jannaschii trna(cys) methanocaldococcus jannaschii 0.01 0.01 1 PMID:18384044 -2.1.1.228 guanine37 in methanocaldococcus jannaschii trnacys methanocaldococcus jannaschii 0.0083 0.0083 1 PMID:16768442 -2.1.1.228 guanine37 in methanocaldococcus jannaschii trnapro escherichia coli 0.01 0.01 1 PMID:17868690 -2.1.1.228 guanine37 in methanocaldococcus jannaschii trnapro methanocaldococcus jannaschii 0.0086 0.0086 1 PMID:17868690 -2.1.1.228 guanine37 in trnaarg haemophilus influenzae 0.078 0.078 1 PMID:26183229 -2.1.1.228 guanine37 in trnacys homo sapiens 0.023 0.023 1 PMID:23887145 -2.1.1.228 guanine37 in trnaglncug haemophilus influenzae 0.34 0.12235 4 PMID:26183229 -2.1.1.228 guanine37 in trnaglng36a haemophilus influenzae 0.36 0.36 1 PMID:26183229 -2.1.1.228 guanine37 in trnaglng36c haemophilus influenzae 0.36 0.36 1 PMID:26183229 -2.1.1.228 guanine37 in trnaglng36u haemophilus influenzae 0.17 0.17 1 PMID:26183229 -2.1.1.228 guanine37 in trnaleu escherichia coli 0.13 0.093 3 PMID:23986443 -2.1.1.228 guanine37 in trnaleu haemophilus influenzae 0.32 0.32 1 PMID:26183229 -2.1.1.228 guanine37 in trnaleu(cag) pseudomonas aeruginosa 0.0113 0.0113 1 PMID:30682246 -2.1.1.228 guanine37 in trnaleu(gac) streptococcus pneumoniae 0.25 0.25 1 PMID:15060037 -2.1.1.228 guanine37 in trnaleu(gag) pseudomonas aeruginosa 0.217 0.217 1 PMID:31399541 -2.1.1.228 guanine37 in trnapro haemophilus influenzae 0.13 0.13 1 PMID:26183229 -2.1.1.228 s-adenosyl-l-homocysteine streptococcus pneumoniae 0.25 0.25 1 PMID:15060037 -2.1.1.228 s-adenosyl-l-methionine escherichia coli 0.09 0.09 1 PMID:20452364 -2.1.1.228 s-adenosyl-l-methionine methanocaldococcus jannaschii 0.02 0.016 2 PMID:16768442;PMID:20452364 -2.1.1.228 s-adenosyl-l-methionine pseudomonas aeruginosa 0.217 0.11375 2 PMID:30682246;PMID:31399541 -2.1.1.231 apigenin artemisia annua 0.0122 0.0122 1 * -2.1.1.231 kaempferol artemisia annua 0.0103 0.0103 1 * -2.1.1.231 luteolin artemisia annua 0.00781 0.00781 1 * -2.1.1.231 quercetin artemisia annua 0.00727 0.00727 1 * -2.1.1.231 quercetin camptotheca acuminata 0.193 0.193 1 PMID:38580009 -2.1.1.231 quercetin streptomyces sp. kctc 0041bp 0.027 0.027 1 PMID:29602384 -2.1.1.231 s-adenosyl-l-methionine camptotheca acuminata 0.108 0.108 1 PMID:38580009 -2.1.1.231 s-adenosyl-l-methionine streptomyces sp. kctc 0041bp 0.027 0.027 1 PMID:29602384 -2.1.1.231 tamarixetin camptotheca acuminata 0.213 0.213 1 PMID:38580009 -2.1.1.232 (2s)-naringenin oryza sativa 25.0 25.0 1 PMID:22493492 -2.1.1.232 (2s)-naringenin oryza sativa japonica group 26.0 14.515 2 PMID:31630460 -2.1.1.232 (2s)-naringenin perilla frutescens 0.0353 0.0353 1 PMID:32998370 -2.1.1.232 apigenin perilla frutescens 0.0091 0.0091 1 PMID:32998370 -2.1.1.232 chrysin perilla frutescens 0.0014 0.0014 1 PMID:32998370 -2.1.1.232 eriodictyol perilla frutescens 0.0054 0.0054 1 PMID:32998370 -2.1.1.232 kaempferol perilla frutescens 0.004 0.004 1 PMID:32998370 -2.1.1.232 luteolin perilla frutescens 0.0029 0.0029 1 PMID:32998370 -2.1.1.232 s-adenosyl-l-methionine oryza sativa 26.0 14.515 2 PMID:31630460 -2.1.1.234 dtdp-3-amino-3,4,6-trideoxy-alpha-d-glucose streptomyces venezuelae 1.533 1.533 1 PMID:12119032 -2.1.1.234 dtdp-3-amino-3,6-dideoxy-alpha-d-glucopyranose streptomyces venezuelae 0.07 0.07 1 PMID:12119032 -2.1.1.235 dtdp-3-amino-3,6-dideoxy-alpha-d-glucopyranose streptomyces fradiae 0.75 0.16849999999999998 4 PMID:12119032;PMID:21142177;PMID:24512254 -2.1.1.235 dtdp-3-methylamino-3,6-dideoxy-alpha-d-glucopyranose streptomyces fradiae 0.54 0.54 1 PMID:12119032 -2.1.1.235 s-adenosyl-l-methionine streptomyces fradiae 0.86 0.475 2 PMID:12119032 -2.1.1.236 dtdp-3-amino-3,6-dideoxy-alpha-d-galactopyranose streptomyces fradiae 0.61 0.61 1 PMID:24512254 -2.1.1.237 mycinamicin iii micromonospora griseorubida 0.225 0.225 1 PMID:19415708 -2.1.1.238 mycinamicin vi micromonospora griseorubida 0.083 0.083 1 PMID:19415708 -2.1.1.240 3-methoxy-4',5-dihydroxy-trans-stilbene vitis vinifera 0.086 0.086 1 PMID:18799660 -2.1.1.240 resveratrol vitis vinifera 0.062 0.062 1 PMID:18799660 -2.1.1.240 trans-resveratrol arabidopsis thaliana 0.0128 0.0128 1 PMID:28202018 -2.1.1.244 (e)-hex-2-en-5-ynyl-s-adenosyl-l-methionine homo sapiens 0.0067 0.0067 1 PMID:31857877 -2.1.1.244 apkrvvqlsl homo sapiens 0.0157 0.0157 1 PMID:39287128 -2.1.1.244 n-terminal-[rcc1] homo sapiens 0.0097 0.0092 2 PMID:31857877 -2.1.1.244 n-terminal-dimethyl-spkriakrrs homo sapiens 0.0098 0.0098 1 PMID:25771539 -2.1.1.244 n-terminal-lpkria homo sapiens 0.0018 0.0018 1 PMID:26543161 -2.1.1.244 n-terminal-methyl-spkriakrrs homo sapiens 0.0097 0.0097 1 PMID:25771539 -2.1.1.244 n-terminal-ppkria homo sapiens 0.0018 0.0018 1 PMID:26543161 -2.1.1.244 n-terminal-rpkria homo sapiens 0.0015 0.0015 1 PMID:26543161 -2.1.1.244 n-terminal-spkria-[rcc1] homo sapiens 0.0093 0.0055 2 PMID:25771539;PMID:26543161 -2.1.1.244 n-terminal-spkriakrr homo sapiens 0.0088 0.0088 1 PMID:25771539 -2.1.1.244 n-terminal-spkriakrrs homo sapiens 0.0073 0.0073 1 PMID:25771539 -2.1.1.244 n-terminal-spkriakrrspp homo sapiens 0.013 0.01125 2 PMID:25771539 -2.1.1.244 n-terminal-wpkria homo sapiens 0.00167 0.00167 1 PMID:26543161 -2.1.1.244 n-terminal-ypkria homo sapiens 0.00067 0.00067 1 PMID:26543161 -2.1.1.244 s-adenosyl-l-methionine homo sapiens 0.0075 0.0075 1 PMID:31857877 -2.1.1.245 a [methyl-co(iii) corrinoid fe-s protein] neomoorella thermoacetica 14.7 14.7 1 PMID:10231523 -2.1.1.245 tetrahydrosarcinapterin neomoorella thermoacetica 14.7 14.7 1 PMID:10231523 -2.1.1.255 (e)-2-methylgeranyl diphosphate streptomyces coelicolor 0.039 0.039 1 PMID:18563898 -2.1.1.255 geranyl diphosphate streptomyces coelicolor 0.0075 0.0075 2 PMID:18563898 -2.1.1.255 s-adenosyl-l-methionine streptomyces coelicolor 0.0075 0.0075 2 PMID:18563898 -2.1.1.258 5-methyltetrahydrofolate neomoorella thermoacetica 14.7 8.1 2 PMID:10231523;PMID:7578120 -2.1.1.258 [co(i) corrinoid fe-s protein] neomoorella thermoacetica 18.0 14.7 3 PMID:10231523;PMID:17172470;PMID:7578120 -2.1.1.258 [methyl-co(iii) corrinoid fe-s protein] neomoorella thermoacetica 0.02 0.02 1 PMID:7578120 -2.1.1.258 cobalamin clostridioides difficile 37.2 19.915000000000003 2 PMID:23599026 -2.1.1.258 hydroxocobalamin neomoorella thermoacetica 1.1 1.1 1 PMID:7578120 -2.1.1.258 hydroxycobalamin clostridioides difficile 77.6 77.6 1 PMID:21324365 -2.1.1.258 methylcobalamin neomoorella thermoacetica 2.2 1.125 2 PMID:17172470;PMID:7578120 -2.1.1.259 [large subunit of spinach rubisco-human carbonic anhydrase ii fusion protein]-l-lysine lathyrus oleraceus 0.011 0.011 1 PMID:17635932 -2.1.1.259 s-adenosyl-l-methionine lathyrus oleraceus 0.019 0.019 1 PMID:17635932 -2.1.1.261 4-dimethylallyl-l-tryptophan aspergillus fumigatus 2.0 2.0 1 PMID:18678866 -2.1.1.261 s-adenosyl-l-methionine aspergillus fumigatus 2.0 2.0 1 PMID:18678866 -2.1.1.267 apigenin perilla frutescens 0.0091 0.0091 1 PMID:32998370 -2.1.1.267 baicalein citrus reticulata 0.0039 0.0039 1 PMID:32075249 -2.1.1.267 caffeic acid citrus reticulata 0.0163 0.0163 1 PMID:32075249 -2.1.1.267 chrysin perilla frutescens 0.0014 0.0014 1 PMID:32998370 -2.1.1.267 cyanidin 3,5-o-diglucoside paeonia suffruticosa 0.128 0.128 1 PMID:26208646 -2.1.1.267 cyanidin 3-o-glucoside paeonia suffruticosa 0.162 0.162 1 PMID:26208646 -2.1.1.267 delphinidin 3-o-beta-d-glucoside solanum lycopersicum 0.025 0.025 1 PMID:25227758 -2.1.1.267 delphinidin 3-o-glucoside paeonia suffruticosa 0.0947 0.0947 1 PMID:26208646 -2.1.1.267 eriodictyol citrus reticulata 0.0076 0.0060999999999999995 2 PMID:32075249 -2.1.1.267 eriodictyol perilla frutescens 0.0054 0.0054 1 PMID:32998370 -2.1.1.267 eriodictyol solanum lycopersicum 0.055 0.055 1 * -2.1.1.267 kaempferol perilla frutescens 0.004 0.004 1 PMID:32998370 -2.1.1.267 luteolin citrus reticulata 0.0205 0.0205 2 PMID:32075249 -2.1.1.267 luteolin perilla frutescens 0.0029 0.0029 1 PMID:32998370 -2.1.1.267 luteolin solanum lycopersicum 0.03 0.03 1 * -2.1.1.267 luteolin synthetic construct 0.51 0.51 1 PMID:36719434 -2.1.1.267 luteolin 7-o-glucoside paeonia suffruticosa 0.00022 0.00022 1 PMID:26208646 -2.1.1.267 myricetin citrus reticulata 0.015 0.015 2 PMID:32075249 -2.1.1.267 naringenin perilla frutescens 0.0353 0.0353 1 PMID:32998370 -2.1.1.267 quercetin citrus reticulata 0.0026 0.0026 2 PMID:32075249 -2.1.1.267 quercetin paeonia suffruticosa 0.00983 0.00983 1 PMID:26208646 -2.1.1.267 quercetin solanum lycopersicum 0.026 0.023 2 PMID:25227758 -2.1.1.267 quercetin 3-o-beta-d-glucoside solanum lycopersicum 0.014 0.014 1 PMID:25227758 -2.1.1.267 quercetin 3-o-rutinoside paeonia suffruticosa 0.192 0.192 1 PMID:26208646 -2.1.1.267 s-adenosyl-l-methionine synthetic construct 0.41 0.41 1 PMID:36719434 -2.1.1.267 tricetin citrus reticulata 0.0212 0.0212 2 PMID:32075249 -2.1.1.269 2-(dimethylsulfonio)propanoate candidatus pelagibacter communis 8.1 8.1 1 PMID:18849431 -2.1.1.269 3-(s,s-dimethylsulfonio)propanoate candidatus pelagibacter communis 8.1 8.1 1 PMID:18849431 -2.1.1.269 3-(s,s-dimethylsulfonio)propanoate ruegeria pomeroyi 2.4 2.4 1 PMID:18849431 -2.1.1.269 dimethylsulfoniopropionate ruegeria pomeroyi 2.4 2.4 1 PMID:18849431 -2.1.1.273 benzoic acid antirrhinum majus 0.0058 0.0058 1 PMID:12361714 -2.1.1.273 benzoic acid arabidopsis lyrata 0.3 0.3 1 PMID:14617060 -2.1.1.273 benzoic acid arabidopsis thaliana 0.19 0.19 1 PMID:14617060 -2.1.1.273 s-adenosyl-l-methionine antirrhinum majus 0.006 0.006 1 PMID:12361714 -2.1.1.273 salicylate clarkia breweri 0.0163 0.0163 1 PMID:30406092 -2.1.1.274 s-adenosyl-l-methionine antirrhinum majus 0.013 0.013 1 PMID:12361714 -2.1.1.274 s-adenosyl-l-methionine solanum lycopersicum 0.028 0.028 1 PMID:20070566 -2.1.1.274 salicylate clarkia breweri 14.0 1.446 4 PMID:10375393;PMID:12897246;PMID:30406092 -2.1.1.274 salicylate solanum lycopersicum 0.056 0.056 1 PMID:20070566 -2.1.1.274 salicylic acid antirrhinum majus 0.011 0.011 1 PMID:12361714 -2.1.1.274 salicylic acid arabidopsis lyrata 0.05 0.05 1 PMID:14617060 -2.1.1.274 salicylic acid arabidopsis thaliana 0.07 0.07 1 PMID:14617060 -2.1.1.275 gibberellin a4 arabidopsis thaliana 0.01 0.01 1 PMID:17220201 -2.1.1.275 gibberellin a9 arabidopsis thaliana 0.026 0.026 1 PMID:17220201 -2.1.1.276 gibberellin a4 arabidopsis thaliana 0.0015 0.0015 1 PMID:17220201 -2.1.1.276 gibberellin a9 arabidopsis thaliana 0.0018 0.0018 1 PMID:17220201 -2.1.1.277 anthranilate zea mays 0.45 0.41000000000000003 2 PMID:20519632 -2.1.1.278 (indol-3-yl)acetate arabidopsis thaliana 0.028 0.028 1 PMID:12897246 -2.1.1.278 (indol-3-yl)acetate oryza sativa japonica group 0.025 0.025 1 PMID:18162595 -2.1.1.278 s-adenosyl-l-methionine oryza sativa japonica group 0.025 0.025 1 PMID:18162595 -2.1.1.279 isoeugenol pimpinella anisum 0.015 0.015 1 PMID:18987218 -2.1.1.28 3-trifluoromethylphenylethanolamine homo sapiens 0.0083 0.008150000000000001 2 PMID:16279783;PMID:24018397 -2.1.1.28 anti-9-amino-6-(trifluoromethyl)benzonorbornene homo sapiens 0.0062 0.0062 1 PMID:16279783 -2.1.1.28 cis-(1r,2s)-2-amino-1-tetralol homo sapiens 0.0048 0.0048 1 PMID:16363801 -2.1.1.28 octopamine homo sapiens 0.021 0.0205 2 PMID:16363801;PMID:24018397 -2.1.1.28 phenylethanolamine homo sapiens 0.047 0.045 3 PMID:15893506;PMID:16363801;PMID:24018397 -2.1.1.28 s-adenosyl-l-methionine homo sapiens 0.0473 0.0473 1 PMID:16279783 -2.1.1.280 dl-selenohomocysteine astragalus bisulcatus 0.0074 0.0074 2 PMID:10026151 -2.1.1.280 dl-selenohomocysteine escherichia coli 0.74 0.74 2 PMID:10026151 -2.1.1.280 l-homocysteine escherichia coli 0.38 0.38 1 PMID:10026151 -2.1.1.280 l-selenocysteine astragalus bisulcatus 0.0062 0.0062 2 PMID:10026151 -2.1.1.280 l-selenocysteine escherichia coli 0.00017 0.00017 2 PMID:10026151 -2.1.1.281 2-oxo-3-phenylpropanoate streptomyces hygroscopicus 0.8 0.8 1 PMID:19731276 -2.1.1.281 s-adenosyl-l-methionine streptomyces hygroscopicus 8.15 8.15 1 PMID:19731276 -2.1.1.284 8-demethylnovobiocic acid streptomyces niveus 0.5 0.5 1 PMID:16274243 -2.1.1.285 demethyldecarbamoylnovobiocin streptomyces niveus 0.4 0.4 1 PMID:14694473 -2.1.1.291 (r)-reticuline papaver somniferum 0.07 0.07 1 PMID:14675446 -2.1.1.291 (s)-reticuline papaver somniferum 0.07 0.07 1 PMID:14675446 -2.1.1.291 guaiacol papaver somniferum 0.1 0.1 1 PMID:14675446 -2.1.1.291 isovanillic acid papaver somniferum 0.02 0.02 1 PMID:14675446 -2.1.1.292 2-chloro-4-nitrophenol streptomyces peucetius 0.00032 0.0003185 2 PMID:27351335;PMID:38412432 -2.1.1.292 4-methylumbelliferone streptomyces peucetius 0.0006 0.0006 1 PMID:38412432 -2.1.1.292 carminomycin streptomyces peucetius 0.0108 0.0108 1 PMID:38412432 -2.1.1.292 s-adenosyl-[(3s)-3-amino-3-(1h-tetrazol-5-yl)propyl](methyl)sulfanium streptomyces peucetius 0.00052 0.00052 1 PMID:27351335 -2.1.1.292 s-adenosyl-l-methionine streptomyces peucetius 0.00028 0.00028 1 PMID:27351335 -2.1.1.293 6-hydroxytryprostatin b aspergillus fumigatus 27.0 27.0 1 PMID:23649274 -2.1.1.293 s-adenosyl-l-methionine aspergillus fumigatus 8.0 8.0 1 PMID:23649274 -2.1.1.300 (s)-tetrahydropapaverine thalictrum flavum subsp. glaucum 0.00079 0.00079 1 PMID:27573242 -2.1.1.302 3-hydroxy-5-methylnaphthoate streptomyces sahachiroi 0.0073 0.0073 1 PMID:20485749 -2.1.1.302 s-adenosyl-l-methionine streptomyces sahachiroi 0.0063 0.0063 1 PMID:20485749 -2.1.1.303 1,4-dihydroxy-2-naphthoic acid streptomyces carzinostaticus 0.000133 0.000133 1 PMID:18387946 -2.1.1.303 2,7-dihydroxy-5-methyl-1-naphthoate streptomyces carzinostaticus 0.0115 0.0115 2 PMID:18387946;PMID:19702337 -2.1.1.303 3,5-dihydroxy-2-naphthoate streptomyces carzinostaticus 0.0045 0.0045 1 PMID:18387946 -2.1.1.303 3,7-dihydroxy-2-naphthoate streptomyces carzinostaticus 0.0004 0.0004 1 PMID:18387946 -2.1.1.315 27-o-demethylrifamycin sv amycolatopsis mediterranei 87.0 87.0 1 PMID:12623077 -2.1.1.316 7-demethylmitomycin a streptomyces lavendulae 0.0017 0.0017 1 PMID:17461583 -2.1.1.316 s-adenosyl-l-methionine streptomyces lavendulae 0.0018 0.0018 1 PMID:17461583 -2.1.1.318 s-adenosyl-l-methionine saccharomyces cerevisiae 7.0 6.7 2 PMID:24412193 -2.1.1.319 [grggfggrggfrggrgg]-l-arginine homo sapiens 0.036 0.021249999999999998 2 PMID:16044463 -2.1.1.319 [histone h2a]-l-arginine homo sapiens 2.66e-05 1.07e-05 3 PMID:37863263 -2.1.1.319 [histone h3]-l-arginine homo sapiens 1.09e-05 5.44e-06 3 PMID:37863263 -2.1.1.319 [histone h4(1-16) peptide]-l-arginine3 homo sapiens 0.00282 0.00282 1 PMID:39491649 -2.1.1.319 [histone h4(1-22) peptide]-l-arginine3 homo sapiens 0.00362 0.00362 1 PMID:39491649 -2.1.1.319 [histone h4]-l-arginine homo sapiens 0.000267 7.98e-05 3 PMID:37863263 -2.1.1.319 [pabpn1 mutant deltac20]-l-arginine homo sapiens 0.0072 0.0072 1 PMID:19158082 -2.1.1.319 [pabpn1 mutant deltac27]-l-arginine homo sapiens 0.0017 0.0017 1 PMID:19158082 -2.1.1.319 [pabpn1 mutant deltac33]-l-arginine homo sapiens 0.00021 0.00021 1 PMID:19158082 -2.1.1.319 [pabpn1 mutant deltac40]-l-arginine homo sapiens 0.00042 0.00042 1 PMID:19158082 -2.1.1.319 [pabpn1 mutant deltac8]-l-arginine homo sapiens 0.023 0.023 1 PMID:19158082 -2.1.1.319 fysgfns-dimethyl-r8-p-dimethyl-r10-grvyatswy homo sapiens 0.0024 0.0024 1 PMID:19158082 -2.1.1.319 fysgfns-dimethyl-r8-prg-dimethyl-r12-vyatswy homo sapiens 0.021 0.021 1 PMID:19158082 -2.1.1.319 fysgfns-dimethyl-r8-prgrvyatswy homo sapiens 0.018 0.018 1 PMID:19158082 -2.1.1.319 fysgfnsrp-dimethyl-r10-g-dimethyl-r12-vyatswy homo sapiens 0.0027 0.0027 1 PMID:19158082 -2.1.1.319 fysgfnsrp-methyl-r10-grvyatswy homo sapiens 0.012 0.012 1 PMID:19158082 -2.1.1.320 [histone h4(1-21)]-l-arginine homo sapiens 0.0483 0.0483 1 PMID:33274632 -2.1.1.320 s-adenosyl-l-methionine homo sapiens 0.0483 0.0483 1 PMID:33274632 -2.1.1.321 [heat shock protein a8]-l-arginine469 mus musculus 0.000611 0.000611 1 PMID:32409666 -2.1.1.321 [histone h2b peptide 23-37]-l-arginine mus musculus 0.01 0.01 1 PMID:24247247 -2.1.1.323 (-)-pluviatolide sinopodophyllum hexandrum 0.72 0.72 1 PMID:26359402 -2.1.1.325 (2e,6e)-farnesoate aedes aegypti 0.000217 0.000217 1 PMID:24657668 -2.1.1.325 (2e,6e)-farnesoate bombyx mori 0.019 0.019 1 PMID:34562453 -2.1.1.325 (2e,6e)-farnesoate diaphorina citri 0.00075 0.00075 1 PMID:25893162 -2.1.1.325 (2e,6e)-farnesoate drosophila melanogaster 0.168 0.168 1 PMID:18549957 -2.1.1.325 (2e,6z)-10cis-juvenile hormone i acid diaphorina citri 3e-06 3e-06 1 PMID:25893162 -2.1.1.325 (2z,6e)-10cis-juvenile hormone i acid diaphorina citri 8e-06 8e-06 1 PMID:25893162 -2.1.1.325 (cis/trans/cis)-juvenile hormone i acid aedes aegypti 0.000245 0.000245 1 PMID:24657668 -2.1.1.325 (cis/trans/trans)-juvenile hormone i acid aedes aegypti 0.000875 0.000875 1 PMID:24657668 -2.1.1.325 (trans/cis/cis)-juvenile hormone i acid aedes aegypti 6e-06 6e-06 1 PMID:24657668 -2.1.1.325 homofarnesoate aedes aegypti 0.00016 0.00016 1 PMID:24657668 -2.1.1.325 homofarnesoate diaphorina citri 0.00022 0.00022 1 PMID:25893162 -2.1.1.325 juvenile hormone i acid bisepoxide aedes aegypti 1.1e-05 1.1e-05 1 PMID:24657668 -2.1.1.325 juvenile hormone iii acid aedes aegypti 0.001148 0.001148 1 PMID:24657668 -2.1.1.325 juvenile hormone iii acid diaphorina citri 1.3e-05 1.3e-05 1 PMID:25893162 -2.1.1.325 juvenile hormone iii acid drosophila melanogaster 0.128 0.128 1 PMID:18549957 -2.1.1.325 juvenile hormone iii acid bisepoxide aedes aegypti 1e-05 1e-05 1 PMID:24657668 -2.1.1.325 laurate drosophila melanogaster 0.0017 0.0017 1 PMID:18549957 -2.1.1.325 palmitate drosophila melanogaster 0.000683 0.000683 1 PMID:18549957 -2.1.1.327 phenazine-1-carboxylate pseudomonas aeruginosa 1.3 1.3 1 PMID:17253782 -2.1.1.329 menadione arabidopsis thaliana 0.44 0.44 1 PMID:26023160 -2.1.1.33 guanine46 in m5u54-modified trnaphe escherichia coli 0.3 0.3 1 PMID:32385137 -2.1.1.33 guanine46 in psi55-modified trnaphe escherichia coli 0.2 0.2 1 PMID:32385137 -2.1.1.33 guanine46 in trnaphe escherichia coli 0.2 0.2 1 PMID:32385137 -2.1.1.334 dithiothreitol pseudomonas deceptionensis 0.2533 0.2533 1 PMID:37179443 -2.1.1.334 h2s marinobacter litoralis 0.16 0.16 1 PMID:39198690 -2.1.1.334 h2s pseudomonas deceptionensis 0.0071 0.0071 1 PMID:37179443 -2.1.1.334 methanethiol marinobacter litoralis 0.08 0.08 1 PMID:39198690 -2.1.1.334 methanethiol pseudomonas deceptionensis 0.093 0.093 1 PMID:37179443 -2.1.1.334 s-adenosyl-l-methionine marinobacter litoralis 0.11 0.08499999999999999 2 PMID:39198690 -2.1.1.336 3,4-dihydroxybenzaldehyde lycoris aurea 0.0173 0.0173 1 PMID:29966257 -2.1.1.336 3,4-dihydroxybenzaldehyde lycoris radiata 0.0179 0.0095 2 PMID:31494163 -2.1.1.336 3,4-dihydroxybenzylaldehyde narcissus papyraceus 0.075 0.0343 4 PMID:39122011 -2.1.1.336 caffeic acid lycoris aurea 0.00038 0.00038 1 PMID:29966257 -2.1.1.336 caffeic acid lycoris radiata 0.0032 0.00275 2 PMID:31494163 -2.1.1.336 dopamine narcissus aff. pseudonarcissus mk-2014 0.06 0.06 1 PMID:25061748 -2.1.1.336 n-methylnorbelladine narcissus aff. pseudonarcissus mk-2014 0.043 0.043 1 PMID:25061748 -2.1.1.336 norbelladine lycoris radiata 0.0084 0.005575 2 PMID:31494163 -2.1.1.336 norbelladine narcissus aff. pseudonarcissus mk-2014 0.022 0.022 1 PMID:25061748 -2.1.1.336 norbelladine narcissus papyraceus 0.036 0.036 1 PMID:39122011 -2.1.1.336 s-adenosyl-l-methionine narcissus aff. pseudonarcissus mk-2014 0.075 0.075 1 PMID:25061748 -2.1.1.337 (r)-reticuline papaver somniferum 0.053 0.053 1 PMID:27634038 -2.1.1.337 (s)-coclaurine papaver somniferum 0.0003 0.0001702 2 PMID:31765874 -2.1.1.337 (s)-n-methylcoclaurine papaver somniferum 0.00113 0.0007149999999999999 2 PMID:31765874 -2.1.1.337 (s)-reticuline papaver somniferum 0.028 0.028 1 PMID:27634038 -2.1.1.337 s-adenosyl-l-methionine papaver somniferum 0.047 0.047 1 PMID:27634038 -2.1.1.341 vanillate sphingobium sp. 0.385 0.385 1 PMID:28429420 -2.1.1.341 vanillate sphingomonas paucimobilis 5.76 5.76 1 PMID:28373573 -2.1.1.343 8-amino-8-demethyl-d-riboflavin streptomyces davaonensis 0.37 0.1855 2 PMID:21911488;PMID:26913589 -2.1.1.343 s-adenosyl-l-methionine streptomyces davaonensis 0.24 0.1205 2 PMID:21911488;PMID:26913589 -2.1.1.346 s-adenosyl-l-methionine homo sapiens 0.0012 0.0012 1 PMID:36584291 -2.1.1.348 adenine in double-stranded dna containing a cyclopyrimidine dimer homo sapiens 0.015 0.015 2 PMID:34086966 -2.1.1.348 adenine in mrna homo sapiens 0.0067 0.0067 1 PMID:34086966 -2.1.1.348 adenine in single-stranded dna homo sapiens 0.0467 0.04 2 PMID:34086966 -2.1.1.35 uracil54 in 11mer of the t-arm of e. coli trna1-val escherichia coli 0.0015 0.0015 1 PMID:2007136;PMID:8794745 -2.1.1.35 uracil54 in 17mer of the t-arm of e. coli trna1-val escherichia coli 0.0333 0.0333 1 PMID:2007136;PMID:8794745 -2.1.1.35 uracil54 in unmodified e. coli trna1-val escherichia coli 0.048 0.048 1 PMID:8794745 -2.1.1.35 uracil54 in yeast trna1-phe escherichia coli 0.0917 0.061700000000000005 2 PMID:2007136;PMID:8604339;PMID:8794745 -2.1.1.35 uridine54 in trna escherichia coli 0.317 0.317 1 PMID:2461858 -2.1.1.354 art(kme1)qtarkstggkaprkqlatkaa-gk-biotin homo sapiens 0.0022 0.0022 1 PMID:27129774 -2.1.1.354 art(kme2)qtarkstggkaprkqlatkaa-gk-biotin homo sapiens 0.053 0.053 1 PMID:27129774 -2.1.1.354 artkqtarkstggkaprkqlatkaa-gk-biotin homo sapiens 0.0025 0.0025 1 PMID:27129774 -2.1.1.354 s-adenosyl-l-methionine homo sapiens 0.053 0.053 1 PMID:27129774 -2.1.1.355 biotinyl-martkqtarkstggkaprkq neurospora crassa 0.038 0.038 1 PMID:15935324 -2.1.1.355 histone h3 mus musculus 0.024 0.022835 2 PMID:16185068 -2.1.1.355 histone h3 (1-13) mus musculus 0.02056 0.02056 1 PMID:16185068 -2.1.1.355 histone h3 (s10phos) mus musculus 0.001806 0.001806 1 PMID:16185068 -2.1.1.355 histone h3 (t11phos) mus musculus 0.005 0.005 1 PMID:16185068 -2.1.1.355 histone h3(k27a) mus musculus 0.0161 0.0161 1 PMID:16185068 -2.1.1.355 histone h3(k4a) mus musculus 0.0161 0.0161 1 PMID:16185068 -2.1.1.355 histone k4-acetylk9 mus musculus 0.0089 0.0089 1 PMID:16185068 -2.1.1.355 histone k4-trimethylk9 mus musculus 0.0089 0.0089 1 PMID:16185068 -2.1.1.355 histone k4ak9 mus musculus 0.01194 0.01194 1 PMID:16185068 -2.1.1.356 (+/-)-2',3'-dibenzyl-s-adenosyl-l-methionine paramecium bursaria chlorella virus 1 0.006 0.006 1 PMID:21958314 -2.1.1.356 (+/-)-2'-benzyl-s-adenosyl-l-methionine paramecium bursaria chlorella virus 1 0.002 0.002 1 PMID:21958314 -2.1.1.356 (+/-)-3'-benzyl-s-adenosyl-l-methionine paramecium bursaria chlorella virus 1 0.002 0.002 1 PMID:21958314 -2.1.1.356 histone h3(k27) paramecium bursaria chlorella virus 1 1.32 1.32 1 PMID:16603186 -2.1.1.356 s-adenosyl-l-methionine paramecium bursaria chlorella virus 1 0.065 0.065 1 PMID:21958314 -2.1.1.357 chicken nucleosome homo sapiens 0.0031 0.0031 1 PMID:26002201 -2.1.1.357 recombinant nucleosome homo sapiens 0.0001 0.0001 1 PMID:26002201 -2.1.1.359 [histone h3]-l-lysine36 homo sapiens 2.083 2.083 1 PMID:24634223 -2.1.1.359 [histone h3]-n6,n6-dimethyl-l-lysine36 homo sapiens 5.278 5.278 1 PMID:24634223 -2.1.1.359 [histone h3]-n6-methyl-l-lysine36 homo sapiens 1.389 1.389 1 PMID:24634223 -2.1.1.359 chicken nucleosome homo sapiens 0.0061 0.0061 1 PMID:26002201 -2.1.1.359 histone h3(peptide 21-44) homo sapiens 0.0031 0.0031 1 PMID:26002201 -2.1.1.359 recombinant nucleosome homo sapiens 0.0013 0.0013 1 PMID:26002201 -2.1.1.365 3,3'-di-o-methyl-4alpha-mannobiose mycolicibacterium hassiacum 0.00062 0.00062 1 PMID:30606802 -2.1.1.366 [histone h3 peptide 1-15]-n6,n6-dimethyl-l-lysine9 homo sapiens 0.038 0.0215 2 PMID:26813693 -2.1.1.366 s-adenosyl-l-methionine homo sapiens 0.065 0.039 2 PMID:26813693 -2.1.1.368 [histone h3 peptide 1-15]-l-lysine9 homo sapiens 0.192 0.1095 2 PMID:26813693 -2.1.1.368 [histone h3 peptide 1-15]-n6-methyl-l-lysine9 homo sapiens 0.293 0.16899999999999998 2 PMID:26813693 -2.1.1.368 s-adenosyl-l-methionine homo sapiens 0.352 0.21350000000000002 4 PMID:26813693 -2.1.1.369 [histone h3.1]-l-lysine27 ricinus communis 0.0778 0.0778 1 PMID:28383693 -2.1.1.37 (cgg*ccg)73 homo sapiens 0.00055 0.00055 1 PMID:11359795 -2.1.1.37 (cgg*cgg)12 homo sapiens 0.00305 0.00305 1 PMID:11359795 -2.1.1.37 dna mus musculus 0.013 0.0115 2 PMID:15671018 -2.1.1.37 linear prw 3602 dna containing cytosine homo sapiens 0.00167 0.00167 1 PMID:11359795 -2.1.1.37 poly(di*dc-di*dc) of chain length 100 mus musculus 0.00597 0.00597 1 PMID:9790680 -2.1.1.37 poly(di*dc-di*dc) of chain length 2000 mus musculus 0.00692 0.00692 1 PMID:9790680 -2.1.1.37 poly(di*dc-di*dc) of chain length 500 mus musculus 0.00633 0.00633 1 PMID:9790680 -2.1.1.37 poly(di*dc-di*dc) of chain length 5000 mus musculus 0.00867 0.00867 1 PMID:9790680 -2.1.1.37 poly(di-dc)*poly(di-dc) homo sapiens 0.145 0.145 1 PMID:11359795 -2.1.1.37 poly(di-dc)poly(di-dc) homo sapiens 0.0511 0.0511 1 PMID:10551868 -2.1.1.37 poly(didc:didc) mus musculus 0.0061 0.0061 1 PMID:12071696 -2.1.1.37 poly-(di-dc)/poly(di-dc) homo sapiens 0.058 0.058 1 PMID:12731873 -2.1.1.37 relaxed circular prw 3602 dna containing cytosine homo sapiens 0.00055 0.00055 1 PMID:11359795 -2.1.1.37 s-adenosyl-l-methionine haemophilus aegyptius 0.0068 0.0068 1 PMID:15602611 -2.1.1.37 s-adenosyl-l-methionine homo sapiens 0.058 0.058 1 PMID:12731873 -2.1.1.37 s-adenosyl-l-methionine mus musculus 0.013 0.0115 2 PMID:15671018 -2.1.1.37 supercoiled prw 3602 dna containing cytosine homo sapiens 0.00278 0.00278 1 PMID:11359795 -2.1.1.37 unmethylated 30-mer dna containing cytosine haemophilus aegyptius 0.0068 0.0068 1 PMID:15602611 -2.1.1.373 (2r)-2-hydroxy-4-(methylsulfanyl)butanoate prymnesium parvum 0.499 0.499 1 PMID:29483657 -2.1.1.373 s-adenosyl-l-methionine prymnesium parvum 0.515 0.515 1 PMID:29483657 -2.1.1.374 2-heptyl-1-hydroxyquinolin-4(1h)-one mycobacterium tuberculosis 0.09 0.09 1 PMID:33064871 -2.1.1.374 2-heptyl-1-hydroxyquinolin-4(1h)-one mycobacteroides abscessus 0.09 0.09 1 PMID:33064871 -2.1.1.374 3-methyl-1-oxo-2-[3-oxo-3-(pyrrolidin-1-yl)propyl]-1,5-dihydrobenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile mycobacterium tuberculosis 0.00123 0.00123 1 PMID:27432954 -2.1.1.381 l-arginine streptomyces achromogenes subsp. streptozoticus 0.098 0.098 1 PMID:30763082 -2.1.1.383 gamma-butyrobetaine eubacterium limosum 3.0 3.0 1 PMID:34688665 -2.1.1.383 l-carnitine eubacterium limosum 6.78 6.78 1 PMID:34688665 -2.1.1.386 [24mer srna]-3'-end ribonucleotide acetivibrio thermocellus 0.0018 0.0018 1 PMID:20007328 -2.1.1.386 [mir173/mir173* duplex]-3'-end ribonucleotide arabidopsis thaliana 0.05 0.0335 2 PMID:20705645 -2.1.1.388 l-proline betaine eubacterium limosum 2.83 2.83 1 PMID:31341018 -2.1.1.392 norajmaline rauvolfia serpentina 2.1 2.1 1 PMID:27122470 -2.1.1.392 s-adenosyl-l-methionine rauvolfia serpentina 1.8 1.8 1 PMID:27122470 -2.1.1.393 norajmaline rauvolfia serpentina 1.0 1.0 1 PMID:27122470 -2.1.1.393 s-adenosyl-l-methionine rauvolfia serpentina 0.7 0.7 1 PMID:27122470 -2.1.1.396 7-o-methyl-n-deacetylisoipecoside carapichea ipecacuanha 0.0204 0.0204 1 PMID:20061395 -2.1.1.396 cephaeline carapichea ipecacuanha 0.00028 0.00028 1 PMID:20061395 -2.1.1.396 n-deacetylisoipecoside carapichea ipecacuanha 0.0113 0.0113 1 PMID:20061395 -2.1.1.396 s-adenosyl-l-homocysteine carapichea ipecacuanha 0.0071 0.0071 1 PMID:20061395 -2.1.1.400 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol methanocaldococcus jannaschii 0.042 0.042 1 PMID:27391308 -2.1.1.400 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol methanococcus maripaludis 0.04 0.04 1 PMID:28682478 -2.1.1.401 nicotinate arabidopsis thaliana 3.52 3.52 1 PMID:28533213 -2.1.1.401 s-adenosyl-l-methionine arabidopsis thaliana 3.01 3.01 1 PMID:28533213 -2.1.1.41 26,27-dehydrozymosterol saccharomyces cerevisiae 0.0008 0.00073335 2 PMID:12196515;PMID:18555004 -2.1.1.41 adomet saccharomyces cerevisiae 0.01 0.01 1 PMID:18563465 -2.1.1.41 lanosterol paracoccidioides brasiliensis 0.0023 0.0023 1 PMID:20624480 -2.1.1.41 zymosterol candida albicans 0.01 0.01 1 PMID:20946868 -2.1.1.41 zymosterol saccharomyces cerevisiae 0.011 0.010915 2 PMID:14717613;PMID:18555004 -2.1.1.41 zymosterol trypanosoma brucei 0.013 0.013 1 PMID:16414960 -2.1.1.42 luteolin oryza sativa japonica group 0.51 0.51 1 PMID:36719434 -2.1.1.42 s-adenosyl-l-methionine oryza sativa japonica group 0.41 0.41 1 PMID:36719434 -2.1.1.44 l-histidine mycolicibacterium smegmatis 0.58 0.58 1 PMID:25404173 -2.1.1.44 nalpha,nalpha-dimethyl-l-histidine mycolicibacterium smegmatis 0.43 0.43 1 PMID:25404173 -2.1.1.44 nalpha-methyl-l-histidine mycolicibacterium smegmatis 0.23 0.23 1 PMID:25404173 -2.1.1.45 2'-deoxyuridine escherichia phage t2 16.0 16.0 1 PMID:4208776 -2.1.1.45 2'-deoxyuridine leishmania major 1.67 1.67 1 PMID:9724533 -2.1.1.45 2'-deoxyuridine rattus norvegicus 0.583 0.583 1 PMID:3567221 -2.1.1.45 5,10-methylenetetrahydrofolate homo sapiens 48.0 0.54 3 PMID:19955218;PMID:29715278 -2.1.1.45 5,10-methylenetetrahydrofolate penaeus vannamei 4.1 4.1 1 PMID:19559812 -2.1.1.45 5,10-methylenetetrahydrofolate plasmodium falciparum 1.2 1.2 1 PMID:18189414 -2.1.1.45 5,10-methylenetetrahydrofolate shrimp white spot syndrome virus 2.8 2.8 1 PMID:19559812 -2.1.1.45 dump homo sapiens 48.0 4.17 3 PMID:19569192;PMID:19955218;PMID:34155 -2.1.1.45 dump mycobacterium tuberculosis 18.0 9.2 2 PMID:18493582 -2.1.1.46 6-hydroxydaidzein glycine max 1.0 1.0 1 PMID:32894761 -2.1.1.49 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline oryctolagus cuniculus 3.67 2.1685 2 PMID:3949799 -2.1.1.49 aniline oryctolagus cuniculus 0.367 0.20015 2 PMID:3949799 -2.1.1.49 desmethylimipramine oryctolagus cuniculus 0.233 0.13315000000000002 2 PMID:3949799 -2.1.1.49 imidazole oryctolagus cuniculus 0.167 0.12515 2 PMID:3949799 -2.1.1.49 pyrazole oryctolagus cuniculus 0.25 0.175 2 PMID:3949799 -2.1.1.49 s-adenosyl-l-methionine oryctolagus cuniculus 0.2 0.1585 2 PMID:3949799 -2.1.1.49 tryptamine oryctolagus cuniculus 0.45 0.42500000000000004 2 PMID:3949799 -2.1.1.5 betaine homo sapiens 88.0 0.0422 3 PMID:18230605;PMID:24895213 -2.1.1.5 betaine rattus norvegicus 0.014 0.014 1 PMID:12487625 -2.1.1.5 l-homocysteine homo sapiens 0.0378 0.0367 3 PMID:24895213 -2.1.1.5 l-homocysteine rattus norvegicus 0.014 0.014 1 PMID:12487625 -2.1.1.5 s-methyl-l-methionine homo sapiens 38.0 24.0 3 PMID:18230605;PMID:24895213 -2.1.1.50 loganate ophiorrhiza pumila 0.00357 0.00357 1 PMID:36194508 -2.1.1.50 loganic acid catharanthus roseus 0.327 0.327 1 PMID:18326827 -2.1.1.53 putrescine calystegia sepium 0.16 0.123 6 PMID:17221359;PMID:19651420 -2.1.1.53 putrescine datura inoxia 0.383 0.383 3 PMID:17221359;PMID:19651420 -2.1.1.53 putrescine datura stramonium 5.14 1.21 6 PMID:17221359;PMID:19651420;PMID:19796640;PMID:23908659 -2.1.1.53 putrescine physalis divaricata 0.198 0.198 1 PMID:17221359;PMID:19651420 -2.1.1.53 putrescine solanum dulcamara 0.047 0.047 2 PMID:17221359;PMID:19651420 -2.1.1.53 putrescine solanum lycopersicum 0.19 0.19 2 PMID:17221359 -2.1.1.53 putrescine solanum tuberosum 0.131 0.131 1 PMID:19651420 -2.1.1.56 5'-(5'-triphosphoguanosine)-[mrna] homo sapiens 0.025 0.025 1 PMID:38402266 -2.1.1.56 g(5')pppr-rna dengue virus 0.0001947 0.0001947 1 PMID:20350738 -2.1.1.56 g(5')pppr-rna orthopoxvirus vaccinia 0.022 0.022 1 PMID:18256245 -2.1.1.56 gpppa saccharomyces cerevisiae 0.0983 0.0983 1 PMID:16971388 -2.1.1.56 gtp chikungunya virus 4.52e-05 4.52e-05 1 PMID:29958924 -2.1.1.56 s-adenosyl-l-methionine chikungunya virus 7.05e-05 7.05e-05 1 PMID:29958924 -2.1.1.56 s-adenosyl-l-methionine dengue virus 5.4e-05 5.4e-05 1 PMID:20350738 -2.1.1.56 s-adenosyl-l-methionine homo sapiens 0.026 0.026 1 PMID:38402266 -2.1.1.56 s-adenosyl-l-methionine orthopoxvirus vaccinia 0.022 0.022 1 PMID:18256245 -2.1.1.6 2-hydroxyestradiol homo sapiens 0.99 0.5375 2 PMID:17880176 -2.1.1.6 4-hydroxyequilenin homo sapiens 0.1 0.1 1 PMID:12755597 -2.1.1.6 4-hydroxyestradiol homo sapiens 0.077 0.056 2 PMID:17880176 -2.1.1.6 catechin homo sapiens 0.26 0.22 2 PMID:17880176 -2.1.1.6 catechol solanum lycopersicum 9.67 9.67 1 PMID:22103597 -2.1.1.6 dopamine homo sapiens 0.708 0.19 12 PMID:17880176;PMID:32371482;PMID:32492152 -2.1.1.6 epicatechin homo sapiens 0.315 0.2425 2 PMID:17880176 -2.1.1.6 epinephrine homo sapiens 0.25 0.1675 2 PMID:17880176 -2.1.1.6 esculetin schizosaccharomyces pombe 0.0289 0.0289 1 PMID:30501007 -2.1.1.6 norepinephrine homo sapiens 0.18 0.11 2 PMID:17880176 -2.1.1.6 s-adenosyl-l-methionine homo sapiens 0.205 0.205 1 PMID:32492152 -2.1.1.61 trna containing 5-aminomethyl-2-thiouridine escherichia coli 1.23 1.23 1 PMID:3298234 -2.1.1.63 snap-vista green saccharolobus solfataricus 8.4 8.4 1 PMID:22167184 -2.1.1.68 5-hydroxyconiferyl alcohol arabidopsis thaliana 2.23 2.23 1 PMID:20652169 -2.1.1.68 5-hydroxyconiferyl aldehyde arabidopsis thaliana 2.85 2.85 1 PMID:20652169 -2.1.1.68 5-hydroxyferulic acid arabidopsis thaliana 1.3 1.3 1 PMID:20652169 -2.1.1.68 caffeic acid arabidopsis thaliana 0.62 0.62 1 PMID:20652169 -2.1.1.68 caffeic acid conioselinum anthriscoides 0.0933 0.0933 1 PMID:34838855 -2.1.1.68 caffeic acid rehmannia glutinosa 0.51 0.51 1 PMID:37522376 -2.1.1.68 caffeic acid methyl ester conioselinum anthriscoides 0.1133 0.1133 1 PMID:34838855 -2.1.1.68 caffeoyl alcohol arabidopsis thaliana 1.52 1.52 1 PMID:20652169 -2.1.1.68 caffeoyl aldehyde arabidopsis thaliana 1.55 1.55 1 PMID:20652169 -2.1.1.68 methyl gallate vanilla planifolia 0.23 0.23 2 PMID:16830185 -2.1.1.68 myricetin vanilla planifolia 0.068 0.068 2 PMID:16830185 -2.1.1.68 n-acetylserotonin arabidopsis thaliana 2.94 2.94 1 PMID:30885319 -2.1.1.68 quercetin arabidopsis thaliana 0.16 0.16 1 PMID:20652169 -2.1.1.7 nicotinate arabidopsis thaliana 3.52 3.52 1 PMID:28533213 -2.1.1.72 adenine in dna clostridioides difficile 0.065 0.065 1 PMID:34103525 -2.1.1.72 adenine in dna escherichia coli 0.0155 0.0155 1 PMID:15456775 -2.1.1.72 adenine in dna klebsiella pneumoniae 0.0056 0.0011 3 PMID:12506109 -2.1.1.72 dna adenine caulobacter vibrioides 0.33 0.33 1 PMID:16987108 -2.1.1.72 dna adenine cereibacter sphaeroides 0.019 0.01125 2 PMID:16464821;PMID:16987108 -2.1.1.72 dna adenine enterobacter cloacae 0.0047 0.0036 2 PMID:16987108 -2.1.1.72 dna adenine escherichia coli 0.93 0.132 28 PMID:16987108;PMID:18502761;PMID:19419959;PMID:19580332 -2.1.1.72 dna adenine klebsiella pneumoniae 0.0056 0.0014600000000000001 4 PMID:16987108 -2.1.1.72 dna adenine moraxella bovis 0.0056 0.0014600000000000001 4 PMID:16987108 -2.1.1.72 dna adenine pyrococcus horikoshii 0.0042 0.0042 1 PMID:21839719 -2.1.1.72 dna adenine streptococcus pneumoniae 0.0056 0.0014600000000000001 4 PMID:16987108 -2.1.1.72 dna adenine tequatrovirus t4 0.015 0.015 1 PMID:12501249 -2.1.1.72 dna adenine thermus aquaticus 0.73 0.73 1 PMID:16987108 -2.1.1.72 double stranded dna adenine escherichia coli 0.0021 0.00033 11 PMID:29844340 -2.1.1.72 oligodeoxynucleotide duplexes 5'-gatc/5'-gatc tequatrovirus t4 0.21 0.21 1 PMID:12893823 -2.1.1.72 s-adenosyl-l-methionine clostridioides difficile 0.09 0.09 1 PMID:34103525 -2.1.1.72 s-adenosyl-l-methionine escherichia coli 0.00117 0.000248 5 PMID:16987108 -2.1.1.72 s-adenosyl-l-methionine pyrococcus horikoshii 0.004 0.004 1 PMID:21839719 -2.1.1.72 single stranded dna adenine escherichia coli 0.0005 0.0005 1 PMID:29844340 -2.1.1.72 t7 dna adenine geobacillus stearothermophilus 0.037 0.037 1 * -2.1.1.75 apigenin plagiochasma appendiculatum 0.117 0.117 1 PMID:28481281 -2.1.1.75 luteolin plagiochasma appendiculatum 0.08 0.08 1 PMID:28481281 -2.1.1.76 3'-o-methylmyricetin solanum habrochaites 1.66 1.66 1 PMID:22711283 -2.1.1.76 7-o-methylmyricetin solanum habrochaites 0.39 0.39 1 PMID:22711283 -2.1.1.76 eriodictyol citrus sinensis 0.0227 0.0227 1 * -2.1.1.76 luteolin citrus sinensis 0.0425 0.0425 1 * -2.1.1.76 myricetin solanum habrochaites 0.82 0.82 1 PMID:22711283 -2.1.1.76 quercetin citrus sinensis 0.063 0.063 1 * -2.1.1.76 rhamnetin citrus sinensis 0.0733 0.0733 1 * -2.1.1.76 s-adenosyl-l-methionine solanum habrochaites 2.94 2.94 1 PMID:22711283 -2.1.1.77 delta sleep inducing peptide l-isoaspartate cyberlindnera jadinii 233.3 233.3 1 * -2.1.1.77 s-adenosyl-l-methionine cyberlindnera jadinii 203.9 203.9 1 * -2.1.1.79 s-adenosyl-l-methionine escherichia coli 2.2 0.0935 4 PMID:15491158;PMID:15606764;PMID:16216082;PMID:16872920 -2.1.1.79 s-adenosyl-l-methionine lactobacillus acidophilus 0.071 0.0595 2 PMID:30828715 -2.1.1.79 s-adenosyl-l-methionine oenococcus oeni 100.0 100.0 1 PMID:26294376 -2.1.1.79 se-adenosyl-l-selenomethionine escherichia coli 0.217 0.217 1 PMID:15491158 -2.1.1.79 te-adenosyl-l-telluromethionine escherichia coli 0.06 0.06 1 PMID:15491158 -2.1.1.8 s-adenosyl-l-methionine homo sapiens 0.61 0.61 1 PMID:27769936 -2.1.1.80 protein l-glutamate salmonella enterica subsp. enterica serovar typhimurium 0.167 0.167 1 PMID:3298235 -2.1.1.82 kaempferol populus sp. 0.064 0.064 1 PMID:20680484 -2.1.1.82 quercetin populus sp. 0.071 0.071 1 PMID:20680484 -2.1.1.85 [beta-actin peptide(abu171)]-l-histidine73 homo sapiens 1.35 1.35 1 PMID:35142326 -2.1.1.85 [beta-actin peptide(ahp171)]-l-histidine73 homo sapiens 2.37 2.37 1 PMID:35142326 -2.1.1.85 [beta-actin peptide(cha171)]-l-histidine73 homo sapiens 1.57 1.57 1 PMID:35142326 -2.1.1.85 [beta-actin peptide(d-ile71)]-l-histidine73 homo sapiens 0.43 0.43 1 PMID:35142326 -2.1.1.85 [beta-actin peptide(ile71)]-l-histidine73 homo sapiens 3.67 3.67 1 PMID:35142326 -2.1.1.85 [beta-actin peptide(leu71)]-l-histidine73 homo sapiens 1.35 1.35 1 PMID:35142326 -2.1.1.85 [beta-actin peptide(nle171)]-l-histidine73 homo sapiens 0.93 0.93 1 PMID:35142326 -2.1.1.85 [beta-actin peptide(nva171)]-l-histidine73 homo sapiens 2.43 2.43 1 PMID:35142326 -2.1.1.85 [beta-actin peptide(val71)]-l-histidine73 homo sapiens 0.97 0.97 1 PMID:35142326 -2.1.1.85 [beta-actin peptide]-3pyrala73 homo sapiens 0.81 0.81 1 PMID:35481649 -2.1.1.85 [beta-actin peptide]-4-triaa73 homo sapiens 2.3 2.3 1 PMID:35481649 -2.1.1.85 [beta-actin peptide]-4pyrala73 homo sapiens 0.79 0.79 1 PMID:35481649 -2.1.1.85 [beta-actin peptide]-l-histidine73 homo sapiens 2.35 2.35 1 PMID:35481649 -2.1.1.85 [beta-actin peptide]-ntau-methyl-l-histidine73 homo sapiens 0.47 0.47 1 PMID:35481649 -2.1.1.85 [beta-actin peptide]-ornithine73 homo sapiens 0.23 0.23 1 PMID:35481649 -2.1.1.85 actin l-histidine73 homo sapiens 0.006 0.006 1 PMID:31388018 -2.1.1.85 beta-actin l-histidine73 homo sapiens 0.013 0.013 1 PMID:30785395 -2.1.1.85 s-adenosyl-l-methionine homo sapiens 0.0112 0.0112 1 PMID:30785395 -2.1.1.85 synthetic peptide corresponding to residue 66-80 of actin homo sapiens 0.00017 0.00017 1 PMID:31388018 -2.1.1.9 sh- phaeodactylum tricornutum 0.0381 0.0381 1 PMID:21227473 -2.1.1.9 thiobenzoic acid physcomitrium patens 0.046 0.046 1 PMID:22795762 -2.1.1.9 thiocyanate oryza sativa 0.000448 0.00041 2 * -2.1.1.9 thiocyanate phaeodactylum tricornutum 0.0102 0.0102 1 PMID:21227473 -2.1.1.90 methylcob(iii)alamin methanosarcina acetivorans 0.315 0.315 1 PMID:30936368 -2.1.2.1 5,10-methylenetetrahydrofolate aphanothece halophytica 0.22 0.17 5 PMID:32417544 -2.1.2.1 5,10-methylenetetrahydrofolate escherichia coli 0.23 0.213 5 PMID:32417544 -2.1.2.1 d-serine plasmodium falciparum 0.246 0.246 1 PMID:19591881 -2.1.2.1 d-serine plasmodium vivax 0.26 0.26 1 PMID:19549189 -2.1.2.1 dl-3-phenylserine glutamicibacter nicotianae 1.6 1.6 1 PMID:25394480 -2.1.2.1 dl-phenylserine idiomarina loihiensis 1.51 1.51 1 PMID:29727646 -2.1.2.1 glycine aphanothece halophytica 0.22 0.17 5 PMID:32417544 -2.1.2.1 glycine escherichia coli 0.23 0.213 5 PMID:32417544 -2.1.2.1 glycine homo sapiens 0.188 0.188 1 PMID:30500180 -2.1.2.1 glycine hydrogenobacter thermophilus 5.0 5.0 1 PMID:22141341 -2.1.2.1 l-ser escherichia coli 5.0 5.0 1 PMID:12773539 -2.1.2.1 l-ser methanocaldococcus jannaschii 3.53 3.53 1 PMID:12902326 -2.1.2.1 l-ser oryctolagus cuniculus 10.0 10.0 1 PMID:15170323 -2.1.2.1 l-ser ovis aries 4.2 4.2 1 PMID:22900314 -2.1.2.1 l-serine alloalcanivorax dieselolei 3.68 3.68 1 PMID:38052329 -2.1.2.1 l-serine aphanothece halophytica 81.23 56.63 11 PMID:32417544 -2.1.2.1 l-serine danio rerio 5.85 5.85 1 PMID:16242955 -2.1.2.1 l-serine escherichia coli 640.0 24.33 14 PMID:19019081;PMID:21059411;PMID:32417544;PMID:3891721 -2.1.2.1 l-serine geobacillus stearothermophilus 5.0 4.1 4 PMID:12089472;PMID:19046138 -2.1.2.1 l-serine glycine max 14.0 14.0 1 PMID:32014996 -2.1.2.1 l-serine homo sapiens 30.0 17.3 10 PMID:24698160;PMID:25619277;PMID:28760597;PMID:8527925 -2.1.2.1 l-serine hydrogenobacter thermophilus 18.7 18.7 1 PMID:22141341 -2.1.2.1 l-serine oryctolagus cuniculus 14.2 12.35 2 PMID:9675060 -2.1.2.1 l-serine ovis aries 4.2 4.15 2 PMID:10998057 -2.1.2.1 l-serine plasmodium falciparum 0.74 0.43 3 PMID:19591881;PMID:19591883 -2.1.2.1 l-serine plasmodium vivax 1.41 0.98 7 PMID:19549189;PMID:25678710;PMID:28760597 -2.1.2.1 l-serine psychromonas ingrahamii 9.25 9.25 1 * -2.1.2.1 l-serine thermoplasma acidophilum 0.112 0.112 1 PMID:34196829 -2.1.2.1 serine danio rerio 8.95 8.95 1 PMID:17664250 -2.1.2.1 tetrahydrofolate aphanothece halophytica 81.23 56.63 11 PMID:32417544 -2.1.2.1 tetrahydrofolate arabidopsis thaliana 15.8 15.8 1 PMID:20518745 -2.1.2.1 tetrahydrofolate escherichia coli 58.8 26.83 11 PMID:12773539;PMID:32417544 -2.1.2.1 tetrahydrofolate glycine max 14.0 14.0 1 PMID:32014996 -2.1.2.1 tetrahydrofolate homo sapiens 30.0 14.17 11 PMID:16137637;PMID:25619277;PMID:28760597;PMID:30500180 -2.1.2.1 tetrahydrofolate oryctolagus cuniculus 0.07 0.07 1 PMID:16137637 -2.1.2.1 tetrahydrofolate plasmodium vivax 1.41 0.895 6 PMID:19549189;PMID:28760597 -2.1.2.1 tetrahydrofolate trichomonas vaginalis 1.3 1.295 2 PMID:16980404 -2.1.2.1 tetrahydromethanopterin methanocaldococcus jannaschii 3.53 3.53 1 PMID:12902326 -2.1.2.10 5,10-methylenetetrahydrofolate escherichia coli 18.4 16.4 2 PMID:10364177;PMID:12531904 -2.1.2.10 5,10-methylenetetrahydropteroyltetraglutamate escherichia coli 10.5 9.625 2 PMID:10364177;PMID:12531904 -2.1.2.10 nh4cl escherichia coli 20.9 20.9 1 PMID:12531904 -2.1.2.10 reduced h-protein escherichia coli 19.4 19.4 1 PMID:12531904 -2.1.2.11 3-methyl-2-oxobutanoate corynebacterium glutamicum 0.43 0.43 1 PMID:36708995 -2.1.2.11 3-methyl-2-oxobutanoate mycobacterium tuberculosis 0.783 0.7815000000000001 2 PMID:12515554 -2.1.2.11 5,10-methylenetetrahydrofolate mycobacterium tuberculosis 0.78 0.78 1 PMID:12515554 -2.1.2.2 (6r)-n10-formyltetrahydrofolate escherichia coli 20.7 17.1 2 PMID:2185839 -2.1.2.2 10-formyl-5,8-dideazafolate homo sapiens 0.102 0.0245 6 PMID:14500878 -2.1.2.2 beta-glycinamide ribonucleotide homo sapiens 7.5 0.262 7 PMID:14500878;PMID:17198385 -2.1.2.2 carbocyclic glycinamide ribonucleotide escherichia coli 33.0 33.0 1 PMID:2185839 -2.1.2.2 n10-formyl-5,8-dideazafolate escherichia coli 40.0 28.05 2 PMID:2185839 -2.1.2.2 n10-formyl-5-deazafolate escherichia coli 1.52 1.52 1 PMID:2185839 -2.1.2.2 n10-formyl-8-deazafolate escherichia coli 0.069 0.069 1 PMID:2185839 -2.1.2.2 n10-formylfolate escherichia coli 0.016 0.016 1 PMID:2185839 -2.1.2.3 10-formyldihydrofolate escherichia coli 7.18 7.18 1 PMID:29799386 -2.1.2.3 10-formyltetrahydrofolate candidatus liberibacter asiaticus 0.311 0.311 1 PMID:38615986 -2.1.2.3 10-formyltetrahydrofolate escherichia coli 4.97 4.97 1 PMID:29799386 -2.1.2.3 5-amino-1-(5-phospho-d-ribosyl)imidazole-4-carboxamide candidatus liberibacter asiaticus 0.311 0.311 1 PMID:38615986 -2.1.2.3 5-amino-1-(5-phospho-d-ribosyl)imidazole-4-carboxamide cryptococcus neoformans 7.5 7.5 1 PMID:36063996 -2.1.2.3 5-amino-1-(5-phospho-d-ribosyl)imidazole-4-carboxamide escherichia coli 3.63 3.63 1 PMID:29799386 -2.1.2.3 5-amino-1-(5-phospho-d-ribosyl)imidazole-4-carboxamide homo sapiens 7.0 6.5 3 PMID:26588576 -2.1.2.3 5-formamido-1-(5-phospho-d-ribosyl)imidazole-4-carboxamide cryptococcus neoformans 7.7 7.7 1 PMID:36063996 -2.1.2.5 5-formimidoyltetrahydrofolate candidatus korobacter versatilis 0.0092 0.0092 1 PMID:20952389 -2.1.2.5 5-formimidoyltetrahydrofolate picrophilus oshimae 0.0193 0.0193 1 PMID:20952389 -2.1.2.5 5-formimidoyltetrahydrofolate streptococcus pyogenes 0.0022 0.0022 1 PMID:20952389 -2.1.2.5 5-formimidoyltetrahydrofolate thermoplasma acidophilum 0.0045 0.0045 1 PMID:20952389 -2.1.2.5 l-glutamate candidatus korobacter versatilis 0.0092 0.0092 1 PMID:20952389 -2.1.2.5 l-glutamate picrophilus oshimae 0.0193 0.0193 1 PMID:20952389 -2.1.2.5 l-glutamate streptococcus pyogenes 0.0022 0.0022 1 PMID:20952389 -2.1.2.5 l-glutamate thermoplasma acidophilum 0.0045 0.0045 1 PMID:20952389 -2.1.2.8 deoxycytidylate tequatrovirus t4 12.7 12.7 1 PMID:7599133 -2.1.2.9 e. coli l-methionyl-trna1val(cau) bos taurus 0.03 0.03 1 PMID:11274157 -2.1.2.9 e. coli l-methionyl-trnafmet bos taurus 0.93 0.93 1 PMID:11274157 -2.1.2.9 e. coli l-methionyl-trnafmet haemophilus influenzae 11.3 11.3 1 * -2.1.2.9 e. coli l-methionyl-trnafmet saccharomyces cerevisiae 0.13 0.13 1 PMID:12549912 -2.1.2.9 e. coli l-methionyl-trnammet bos taurus 0.04 0.04 1 PMID:11274157 -2.1.2.9 l-isoleucyl-trnafmet saccharomyces cerevisiae 0.0005 0.0005 1 PMID:12549912 -2.1.2.9 l-methionyl-trnafmet escherichia coli 41.5 28.65 6 PMID:10694387;PMID:10891086;PMID:6989606;PMID:9391059;PMID:9843398 -2.1.2.9 l-valyl-trnafmet saccharomyces cerevisiae 0.009 0.009 1 PMID:12549912 -2.1.3.12 decarbamoylnovobiocin streptomyces niveus 4.1 3.25 2 PMID:14694473;PMID:15157876 -2.1.3.12 novclobiocin 104 streptomyces niveus 1.32 1.32 1 PMID:15157876 -2.1.3.12 novclobiocin 105 streptomyces niveus 1.53 1.53 1 PMID:15157876 -2.1.3.2 aspartate mesocricetus auratus 79.7 79.7 1 PMID:6300078 -2.1.3.2 carbamoyl phosphate mesocricetus auratus 35.9 35.9 1 PMID:6300078 -2.1.3.2 carbamoyl phosphate pseudomonas aeruginosa 87.6 87.6 1 PMID:32126100 -2.1.3.2 carbamoyl phosphate triticum aestivum 47.2 47.2 1 PMID:9914477 -2.1.3.2 carbamoylphosphate mesocricetus auratus 57.4 57.4 1 PMID:6300078 -2.1.3.2 l-aspartate aquifex aeolicus 41.7 23.650000000000002 2 PMID:14534296 -2.1.3.2 l-aspartate escherichia coli 417.0 417.0 1 * -2.1.3.2 l-aspartate mesocricetus auratus 156.0 156.0 1 PMID:6300078 -2.1.3.2 l-aspartate pseudomonas aeruginosa 113.0 113.0 1 PMID:32126100 -2.1.3.3 carbamoyl phosphate escherichia coli 410.0 410.0 1 PMID:32027716 -2.1.3.3 carbamoyl phosphate giardia duodenalis 82.0 82.0 1 PMID:19507245 -2.1.3.3 carbamoyl phosphate homo sapiens 29.0 29.0 1 PMID:38940639 -2.1.3.3 diaminobutane pseudomonas savastanoi 0.025 0.025 1 PMID:15766270 -2.1.3.3 l-citrulline enterococcus faecalis 90.0 90.0 1 PMID:4622304 -2.1.3.3 l-citrulline giardia duodenalis 8.1 8.1 1 PMID:19507245 -2.1.3.3 l-lysine pseudomonas savastanoi 0.0036 0.0036 1 PMID:15766270 -2.1.3.3 l-ornithine escherichia coli 440.0 440.0 1 PMID:32027716 -2.1.3.3 l-ornithine giardia duodenalis 94.2 94.2 1 PMID:19507245 -2.1.3.3 l-ornithine homo sapiens 34.0 34.0 1 PMID:38940639 -2.1.3.3 l-ornithine moritella abyssi 750.0 618.0 6 PMID:12644485 -2.1.3.3 l-ornithine pseudomonas savastanoi 49.0 49.0 1 PMID:15766270 -2.1.3.3 ornithine alnus glutinosa 18.0 18.0 1 * -2.1.3.3 ornithine bos taurus 187.0 187.0 1 PMID:4622304 -2.1.3.3 ornithine enterococcus faecalis 3400.0 3400.0 1 PMID:4622304 -2.1.3.3 ornithine pyrococcus furiosus 500.0 435.0 2 PMID:11208811 -2.1.3.3 phosphate giardia duodenalis 7.9 7.9 1 PMID:19507245 -2.1.3.5 carbamoyl phosphate escherichia coli 35.5 35.5 1 PMID:38888336 -2.1.3.5 oxamate escherichia coli 58.5 58.5 1 PMID:38888336 -2.1.4.1 glycine cylindrospermopsis raciborskii 875.0 875.0 1 PMID:20718864 -2.1.4.1 l-arginine cylindrospermopsis raciborskii 875.0 875.0 1 PMID:20718864 -2.1.5.1 (+)-sesamin sinomonas sp. no.22 7.9 7.9 1 PMID:27444012 -2.10.1.1 molybdate arabidopsis thaliana 2.5 1.375 2 PMID:16636046 -2.2.1.1 2-deoxy-d-erythrose 4-phosphate saccharomyces cerevisiae 4.9 3.1 2 PMID:9537513 -2.2.1.1 2-deoxy-d-ribose 5-phosphate saccharomyces cerevisiae 0.4 0.35 2 PMID:9537513 -2.2.1.1 d-arabinose 5-phosphate saccharomyces cerevisiae 0.4 0.225 2 PMID:9537513 -2.2.1.1 d-erythrose 4-phosphate saccharomyces cerevisiae 69.0 35.2 2 PMID:9537513 -2.2.1.1 d-erythrose 4-phosphate salmonella enterica subsp. enterica serovar typhimurium 104000.0 86500.0 3 PMID:29848552 -2.2.1.1 d-fructose 6-phosphate bacillus methanolicus 112.0 97.0 2 PMID:24405865 -2.2.1.1 d-fructose 6-phosphate scheffersomyces stipitis 26.87 26.87 1 PMID:27578891 -2.2.1.1 d-glyceraldehyde 3-phosphate bacillus methanolicus 99.0 73.5 2 PMID:24405865 -2.2.1.1 d-ribose 5-phosphate bacillus methanolicus 21.0 17.0 2 PMID:24405865 -2.2.1.1 d-ribose 5-phosphate saccharomyces cerevisiae 56.7 46.0 3 PMID:9537513 -2.2.1.1 d-ribose 5-phosphate salmonella enterica subsp. enterica serovar typhimurium 95400.0 67100.0 3 PMID:29848552 -2.2.1.1 d-ribose 5-phosphate spinacia oleracea 0.0148 0.0148 1 PMID:9523694 -2.2.1.1 d-ribose-5-phosphate leishmania mexicana 8.4 8.4 1 PMID:15149284 -2.2.1.1 d-threose 4-phosphate saccharomyces cerevisiae 0.3 0.185 2 PMID:9537513 -2.2.1.1 d-xylulose 5-phosphate bacillus methanolicus 54.0 47.0 2 PMID:24405865 -2.2.1.1 d-xylulose 5-phosphate homo sapiens 6.3 4.7 2 PMID:20667822 -2.2.1.1 d-xylulose 5-phosphate saccharomyces cerevisiae 45.0 5.0 3 PMID:15752351 -2.2.1.1 d-xylulose 5-phosphate salmonella enterica subsp. enterica serovar typhimurium 131000.0 61950.0 6 PMID:29848552 -2.2.1.1 d-xylulose 5-phosphate scheffersomyces stipitis 25.31 21.665 2 PMID:27578891 -2.2.1.1 glycolaldehyde thermotoga maritima 0.45 0.45 1 PMID:34250527 -2.2.1.1 hydroxypyruvate saccharomyces cerevisiae 44.5 2.5 3 PMID:15752351 -2.2.1.1 lithium beta-hydroxypyruvate escherichia coli 410000.0 410000.0 1 PMID:19927318 -2.2.1.1 lithium hydroxypyruvate thermotoga maritima 0.77 0.77 1 PMID:34250527 -2.2.1.1 sedoheptulose 7-phosphate scheffersomyces stipitis 28.642 28.642 1 PMID:27578891 -2.2.1.1 xylulose 5-phosphate saccharomyces cerevisiae 56.7 56.7 1 * -2.2.1.1 xylulose 5-phosphate spinacia oleracea 0.0187 0.0187 1 PMID:9523694 -2.2.1.2 d-erythrose 4-phosphate thermotoga maritima 22.9 22.9 1 PMID:21947648 -2.2.1.2 d-erythrose-4-phosphate blastobotrys adeninivorans 6.44 6.44 1 PMID:17221198 -2.2.1.2 d-fructose 6-phosphate blastobotrys adeninivorans 4.9 4.9 2 PMID:17221198 -2.2.1.2 d-fructose 6-phosphate thermoplasma acidophilum 13.86 13.86 1 PMID:26131847 -2.2.1.2 d-fructose 6-phosphate thermotoga maritima 22.3 22.3 1 PMID:21947648 -2.2.1.2 glyceraldehyde 3-phosphate escherichia coli 13.0 13.0 1 PMID:21290439 -2.2.1.5 2-oxoglutarate mycobacterium tuberculosis 4.25 4.25 1 PMID:23760263 -2.2.1.5 glyoxylate mycobacterium tuberculosis 5.29 5.29 1 PMID:23760263 -2.2.1.6 2-oxobutanoate bacillus subtilis 51.0 51.0 1 PMID:39617118 -2.2.1.6 2-oxobutanoate escherichia coli 3.3 3.3 1 PMID:20504042 -2.2.1.6 hydroxypyruvate escherichia coli 5.47 5.47 1 PMID:15895677 -2.2.1.6 pyruvate arabidopsis thaliana 9.4 9.4 1 PMID:35690625 -2.2.1.6 pyruvate bacillus licheniformis 514.0 514.0 1 PMID:29026998 -2.2.1.6 pyruvate bacillus subtilis 140.0 121.0 3 PMID:19684168;PMID:39617118 -2.2.1.6 pyruvate enterococcus faecalis 5.3 5.28 3 PMID:23199739;PMID:25128823 -2.2.1.6 pyruvate escherichia coli 71.0 37.315 8 PMID:15640355;PMID:20504042;PMID:21370850;PMID:22443469;PMID:32538427;PMID:9581571 -2.2.1.6 pyruvate listeria seeligeri 10.1 10.1 1 PMID:39617118 -2.2.1.6 pyruvate mycobacterium tuberculosis 3.2 3.196 5 PMID:23931689;PMID:24731825 -2.2.1.6 pyruvate nicotiana tabacum 16.1 9.21 2 PMID:15521822 -2.2.1.6 pyruvate oryza sativa indica group 8.8 6.65 2 PMID:29170911 -2.2.1.6 pyruvate oryza sativa japonica group 6.7 6.7 1 PMID:32070060 -2.2.1.6 pyruvate thermotoga maritima 98.0 98.0 3 * -2.2.1.7 1-methyl-2-nitrosobenzene escherichia coli 0.6 0.6 1 PMID:23824585 -2.2.1.7 1-nitrosonaphthalen-2-ol escherichia coli 0.018 0.018 1 PMID:23824585 -2.2.1.7 2-hydroxy-4,6-dinitrobenzaldehyde escherichia coli 0.006 0.006 1 PMID:23824585 -2.2.1.7 3,5-dimethyl-4-nitroso-1-(propan-2-yl)-1h-pyrazole escherichia coli 0.023 0.023 1 PMID:23824585 -2.2.1.7 6-bromo-1-nitrosonaphthalen-2-ol escherichia coli 0.033 0.033 1 PMID:23824585 -2.2.1.7 6-hydroxy-5-nitrosonaphthalene-2-sulfonamide escherichia coli 0.02 0.02 1 PMID:23824585 -2.2.1.7 7-methoxy-1-nitrosonaphthalen-2-ol escherichia coli 0.022 0.022 1 PMID:23824585 -2.2.1.7 d-glyceraldehyde rhodobacter capsulatus 1.7 1.7 1 PMID:12549936 -2.2.1.7 d-glyceraldehyde 3-phosphate agrobacterium tumefaciens 26.8 26.8 1 PMID:17188774 -2.2.1.7 d-glyceraldehyde 3-phosphate botryococcus braunii 6.0 2.0 3 PMID:22325894 -2.2.1.7 d-glyceraldehyde 3-phosphate deinococcus radiodurans 7.9 5.235 4 PMID:24767541;PMID:27537621;PMID:29552677;PMID:31239351 -2.2.1.7 d-glyceraldehyde 3-phosphate escherichia coli 1.38 1.19 2 PMID:31724401;PMID:39764603 -2.2.1.7 d-glyceraldehyde 3-phosphate mycobacterium tuberculosis 0.0173 0.0173 1 PMID:35508530 -2.2.1.7 d-glyceraldehyde 3-phosphate plasmodium falciparum 4.1 4.1 1 PMID:26699947 -2.2.1.7 d-glyceraldehyde 3-phosphate plasmodium vivax 11.0 8.7 2 PMID:23772383;PMID:26699947 -2.2.1.7 d-glyceraldehyde 3-phosphate populus trichocarpa 0.64 0.64 1 PMID:23612965 -2.2.1.7 d-glyceraldehyde 3-phosphate pseudomonas aeruginosa 1.1 1.1 1 PMID:39764603 -2.2.1.7 d-glyceraldehyde 3-phosphate rhodobacter capsulatus 1.9 1.9 1 PMID:12549936 -2.2.1.7 n,n-dimethyl-4-nitrosoaniline escherichia coli 0.015 0.015 1 PMID:23824585 -2.2.1.7 pyruvate agrobacterium tumefaciens 26.8 26.8 2 PMID:17188774 -2.2.1.7 pyruvate botryococcus braunii 5.6 2.4 3 PMID:22325894 -2.2.1.7 pyruvate deinococcus radiodurans 7.4 7.4 3 PMID:24767541;PMID:27537621;PMID:29552677 -2.2.1.7 pyruvate escherichia coli 2.6 2.6 1 PMID:21878632 -2.2.1.7 pyruvate mycobacterium tuberculosis 0.0045 0.0045 1 PMID:35508530 -2.2.1.7 pyruvate plasmodium falciparum 4.2 4.2 1 PMID:26699947 -2.2.1.7 pyruvate plasmodium vivax 9.5 8.05 2 PMID:23772383;PMID:26699947 -2.2.1.7 pyruvate populus trichocarpa 0.53 0.53 1 PMID:23612965 -2.2.1.7 pyruvate rhodobacter capsulatus 1.9 1.7999999999999998 2 PMID:12549936 -2.2.1.8 chloroacetaldehyde streptomyces sp. ma37 0.024 0.024 1 PMID:32140842 -2.2.1.8 fluoroacetaldehyde streptomyces sp. ma37 0.03 0.03 1 PMID:32140842 -2.2.1.8 glycolaldehyde streptomyces sp. ma37 0.024 0.024 1 PMID:32140842 -2.2.1.8 isobutyraldehyde streptomyces sp. ma37 0.013 0.013 1 PMID:32140842 -2.2.1.8 l-allo-threonine streptomyces sp. ma37 0.007 0.007 1 PMID:32140842 -2.2.1.8 l-threonine streptomyces sp. ma37 0.052 0.052 1 PMID:32140842 -2.2.1.8 phenylacetaldehyde streptomyces sp. ma37 0.01 0.01 1 PMID:32140842 -2.2.1.8 propanal streptomyces sp. ma37 0.02 0.02 1 PMID:32140842 -2.2.1.9 (+)-5-(carboxymethoxy)-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid escherichia coli 0.4 0.4 1 PMID:21928762 -2.2.1.9 2-oxoglutarate bacillus subtilis 0.23 0.23 1 PMID:20600129 -2.2.1.9 2-oxoglutarate escherichia coli 0.287 0.28 3 PMID:17760421;PMID:21928762;PMID:30341164 -2.2.1.9 2-oxoglutarate mycobacterium tuberculosis 0.28 0.28 1 PMID:21928762 -2.2.1.9 isochorismate escherichia coli 0.337 0.1935 2 PMID:17760421;PMID:30341164 -2.3.1.1 l-glutamate mycobacterium tuberculosis 0.22 0.22 1 PMID:15838030 -2.3.1.1 l-glutamine mycobacterium tuberculosis 0.78 0.78 1 PMID:15838030 -2.3.1.101 5,6,7,8-tetrahydromethanopterin methanosarcina barkeri 1970.0 1970.0 1 PMID:2261993 -2.3.1.101 5,6,7,8-tetrahydromethanopterin methanothermobacter thermautotrophicus 2770.0 2770.0 1 PMID:2261993 -2.3.1.102 1-amino-5(hydroxyamino)pentane escherichia coli 7.97e-05 7.97e-05 1 PMID:3521734 -2.3.1.102 hydroxylamine escherichia coli 0.00177 0.00177 1 PMID:3521734 -2.3.1.102 n-methylhydroxylamine escherichia coli 3.85e-05 3.85e-05 1 PMID:3521734 -2.3.1.102 n5-hydroxyornithine escherichia coli 0.000112 0.000112 1 PMID:3521734 -2.3.1.102 n6-hydroxylysine escherichia coli 4.77e-05 4.77e-05 1 PMID:3521734 -2.3.1.108 alpha-tubulin l-lysine homo sapiens 3.8 3.5 2 PMID:24846647 -2.3.1.115 daidzein 7-o-glucoside glycine max 34.24 31.92 2 PMID:28559900 -2.3.1.115 genistein 7-o-glucoside glycine max 56.4 48.675 2 PMID:28559900 -2.3.1.115 glycitein 7-o-glucoside glycine max 68.4 67.525 2 PMID:28559900 -2.3.1.115 malonyl-coa glycine max 19.21 13.655000000000001 2 PMID:28559900 -2.3.1.116 malonyl-coa glandularia x hybrida 2.9 2.9 1 * -2.3.1.116 malonyl-coa lamium purpureum 9.0 9.0 1 * -2.3.1.116 quercetin 3-o-glucoside glandularia x hybrida 2.9 2.9 1 * -2.3.1.116 quercetin 3-o-glucoside lamium purpureum 9.0 9.0 1 * -2.3.1.117 succinyl-coa pseudomonas amygdali pv. tabaci 0.22 0.22 1 PMID:29307827 -2.3.1.118 3-amino-4-hydroxyphenylarsonic acid enterobacter sp. cz-1 54.5 27.92 2 PMID:31676473 -2.3.1.12 acetyl-coa azotobacter vinelandii 2.4 2.4 1 PMID:7703242 -2.3.1.122 alpha,alpha-trehalose 6-monomycolate mycolicibacterium smegmatis 1.09 1.09 1 PMID:19857528 -2.3.1.129 udp-n-acetylglucosamine escherichia coli 10.5 9.83 3 PMID:10480918 -2.3.1.13 acetyl-coa mus musculus 0.8 0.8 2 PMID:24576660 -2.3.1.13 benzoyl-coa mus musculus 4.2 4.2 2 PMID:24576660 -2.3.1.13 butyryl-coa mus musculus 15.0 15.0 2 PMID:24576660 -2.3.1.13 glycine mus musculus 3.2 3.2 1 PMID:24576660 -2.3.1.13 glycine ethyl ester mus musculus 0.57 0.57 1 PMID:24576660 -2.3.1.13 glycine methyl ester mus musculus 1.0 1.0 1 PMID:24576660 -2.3.1.13 hexanoyl-coa mus musculus 4.6 4.6 2 PMID:24576660 -2.3.1.135 all-trans-retinol homo sapiens 40.4 40.4 1 PMID:24613493 -2.3.1.136 ([glc-(alpha1-4)-sia]n) neisseria meningitidis 2.1 2.1 1 PMID:19525232 -2.3.1.136 acetyl-coa escherichia coli 0.51 0.51 1 PMID:17519228 -2.3.1.136 acetyl-coa neisseria meningitidis 1.3 1.3 1 PMID:19525232 -2.3.1.136 colominic acid escherichia coli 1.99 1.99 1 PMID:17519228 -2.3.1.137 octanoyl-coa mus musculus 0.367 0.367 1 PMID:6838215 -2.3.1.15 oleoyl-[acyl-carrier protein] helianthus annuus 0.0918 0.0918 1 PMID:25618244 -2.3.1.15 oleoyl-coa mycobacterium tuberculosis 0.218 0.218 1 PMID:38676355 -2.3.1.15 palmitoleoyl-coa mycobacterium tuberculosis 0.175 0.175 1 PMID:38676355 -2.3.1.15 palmitoyl-[acyl-carrier protein] helianthus annuus 0.00944 0.00944 1 PMID:25618244 -2.3.1.15 sn-glycerol 3-phosphate helianthus annuus 0.011 0.011 1 PMID:25618244 -2.3.1.15 sn-glycerol 3-phosphate mycobacterium tuberculosis 0.238 0.20400000000000001 2 PMID:38676355 -2.3.1.15 stearoyl-[acyl-carrier protein] helianthus annuus 0.00674 0.00674 1 PMID:25618244 -2.3.1.150 nudaurine papaver somniferum 3.3 3.3 1 PMID:11404355 -2.3.1.150 salutaridinol papaver somniferum 4.4 4.4 1 PMID:11404355 -2.3.1.151 benzoyl-coa garcinia mangostana 0.049 0.049 1 PMID:22390826 -2.3.1.151 benzoyl-coa hypericum androsaemum 9.66 4.8575 2 PMID:12795704;PMID:19710020 -2.3.1.151 malonyl-coa garcinia mangostana 0.058 0.058 1 PMID:22390826 -2.3.1.157 acetoacetyl-coa mycobacterium tuberculosis 0.5 0.5 1 PMID:29684272 -2.3.1.157 acetyl-coa bacillus subtilis 2.459 2.459 1 * -2.3.1.157 acetyl-coa mycobacterium tuberculosis 82.47 45.235 2 PMID:21594607;PMID:29684272 -2.3.1.157 acetyl-coa yersinia pestis 853.0 853.0 1 PMID:25417006 -2.3.1.157 acetyl-coa yersinia pseudotuberculosis 853.0 853.0 1 PMID:25417006 -2.3.1.157 alpha-d-galactosamine 1-phosphate sulfurisphaera tokodaii 69.7 69.7 1 PMID:25567746 -2.3.1.157 alpha-d-glucosamine 1-phosphate bacillus subtilis 0.81 0.81 1 * -2.3.1.157 alpha-d-glucosamine 1-phosphate mycobacterium tuberculosis 82.47 4.25 4 PMID:21594607;PMID:29684272 -2.3.1.157 alpha-d-glucosamine 1-phosphate sulfurisphaera tokodaii 123.2 123.2 3 PMID:20400541;PMID:25567746 -2.3.1.157 alpha-d-glucosamine 1-phosphate yersinia pestis 828.0 828.0 1 PMID:25417006 -2.3.1.157 alpha-d-glucosamine 1-phosphate yersinia pseudotuberculosis 828.0 828.0 1 PMID:25417006 -2.3.1.157 n-acetyl-d-glucosamine 1-phosphate escherichia coli 12.4 12.4 1 PMID:8083170 -2.3.1.157 propionyl-coa mycobacterium tuberculosis 0.5 0.5 1 PMID:29684272 -2.3.1.157 succinyl-coa mycobacterium tuberculosis 0.9 0.9 1 PMID:29684272 -2.3.1.159 4-coumaroyl-coa citrus x microcarpa 0.113 0.113 1 PMID:23963450 -2.3.1.159 4-coumaroyl-coa huperzia serrata 0.034 0.034 1 PMID:17250741 -2.3.1.159 n-methylanthraniloyl-coa citrus x microcarpa 0.067 0.045 2 PMID:23963450 -2.3.1.16 acetoacetyl-coa homo sapiens 14.8 14.8 1 PMID:25478839 -2.3.1.16 acetyl-coa homo sapiens 1.4 1.4 1 PMID:25478839 -2.3.1.16 acetyl-coa thermobifida fusca 0.0035 0.0035 1 PMID:38694995 -2.3.1.16 glutaryl-coa thermobifida fusca 0.0035 0.0035 1 PMID:38694995 -2.3.1.16 malonyl-coa thermobifida fusca 0.0032 0.0032 1 PMID:38694995 -2.3.1.16 succinyl-coa thermobifida fusca 0.0053 0.0053 1 PMID:38694995 -2.3.1.160 gardneral rauvolfia serpentina x rhazya stricta 0.103 0.103 1 PMID:15110860 -2.3.1.160 vinorine rauvolfia serpentina x rhazya stricta 0.735 0.735 1 PMID:15110860 -2.3.1.161 (4e,6e)-3-oxoocta-4,6-dienoyl-n-acetylcysteamine aspergillus terreus 3.25 3.25 1 PMID:26630357 -2.3.1.161 2-methyl-3-oxohexanoyl-n-acetylcysteamine aspergillus terreus 0.085 0.085 1 PMID:26630357 -2.3.1.161 3-oxohexanoyl-n-acetylcysteamine aspergillus terreus 0.57 0.57 1 PMID:26630357 -2.3.1.161 3-oxooctanoyl-n-acetylcysteamine aspergillus terreus 0.32 0.32 1 PMID:26630357 -2.3.1.162 taxadien-2alpha,5alpha,10beta-triol taxus cuspidata 27.92 16.845 2 PMID:15369823 -2.3.1.162 taxadien-2alpha,5alpha-diol taxus cuspidata 52.13 52.13 1 PMID:15369823 -2.3.1.162 taxadien-5alpha,9alpha,10beta,13alpha-tetraol taxus cuspidata 15.47 13.690000000000001 2 PMID:15369823 -2.3.1.162 taxadien-5alpha-acetoxy-9alpha,10beta,13alpha-triol taxus cuspidata 297.9 221.45 2 PMID:15369823 -2.3.1.162 taxadien-5alpha-ol taxus cuspidata 29.59 16.935 2 PMID:15369823 -2.3.1.165 6-methylsalicylate aspergillus terreus 0.023 0.023 1 PMID:20304931 -2.3.1.166 (2alpha,5beta,7beta,10beta,13alpha)-4,7,10,13-tetrakis(acetyloxy)-1-hydroxy-9-oxo-5,20-epoxytax-11-en-2-yl 3-methylbenzoate taxus cuspidata 4e-05 4e-05 1 PMID:20108947 -2.3.1.167 10-deacetylbaccatin iii taxus cuspidata 0.58 0.58 1 PMID:19007225 -2.3.1.167 10-deacetylbaccatin iii taxus mairei 14.69 14.69 1 PMID:29797298 -2.3.1.167 10-deacetyltaxol taxus cuspidata 0.000334 0.000334 1 PMID:28516951 -2.3.1.167 acetyl-coa taxus mairei 16.12 8.065050000000001 2 PMID:29796788;PMID:29797298 -2.3.1.167 vinyl acetate taxus mairei 0.0224 0.0224 1 PMID:29796788 -2.3.1.169 acetyl-coa carboxydothermus hydrogenoformans 0.142 0.07106 2 PMID:20202935 -2.3.1.169 acetyl-coa methanosarcina thermophila 0.0002 0.0002 1 PMID:20202935 -2.3.1.17 2,3-diaminosuccinate homo sapiens 0.035 0.035 1 PMID:26550943 -2.3.1.17 3-methyl-l-aspartate homo sapiens 0.0018 0.0018 1 PMID:26550943 -2.3.1.17 acetyl-coa homo sapiens 0.0071 0.0071 1 PMID:26550943 -2.3.1.17 l-aspartate homo sapiens 0.0071 0.0071 1 PMID:26550943 -2.3.1.17 l-glutamate homo sapiens 0.023 0.023 1 PMID:26550943 -2.3.1.171 cyanidin 3-o-beta-d-glucoside chrysanthemum x morifolium 11.1 11.05 2 PMID:17383962 -2.3.1.171 malonyl-coa dahlia pinnata 7.3 7.3 1 PMID:12481098 -2.3.1.171 malonyl-coa pericallis cruenta 8.8 8.8 1 * -2.3.1.171 pelargonidin 3-o-beta-d-glucoside dahlia pinnata 7.3 7.3 1 PMID:12481098 -2.3.1.171 pelargonidin 3-o-beta-d-glucoside pericallis cruenta 8.8 8.8 1 * -2.3.1.172 cyanidin 3-o-[[2-o-(2-o-sinapoyl)-beta-d-xylosyl]-6-o-(6-o-(4-coumaroyl)-beta-d-glucoside)] 5-o-beta-d-glucoside arabidopsis thaliana 0.00012 0.00012 1 PMID:17292360 -2.3.1.172 cyanidin 3-o-[[2-o-beta-d-xylosyl]-6-o-(6-o-(4-coumaroyl)-beta-d-glucoside)] 5-o-beta-d-glucoside arabidopsis thaliana 0.12 0.12 1 PMID:17292360 -2.3.1.172 cyanin arabidopsis thaliana 0.02 0.02 1 PMID:17292360 -2.3.1.172 malonyl-coa arabidopsis thaliana 0.2 0.10065 2 PMID:17292360 -2.3.1.172 malvin arabidopsis thaliana 1.79 1.79 1 PMID:17292360 -2.3.1.172 pelargonidin 3-o-(6-caffeoyl-beta-d-glucoside) 5-o-beta-d-glucoside salvia splendens 7.8 7.8 1 PMID:11598135 -2.3.1.172 shisonin salvia splendens 8.7 8.7 3 PMID:11598135;PMID:12578391 -2.3.1.174 3-oxoadipyl-coa pseudomonas sp. 7.8 7.8 1 PMID:11741862 -2.3.1.174 coa pseudomonas sp. 7.8 7.8 1 PMID:11741862 -2.3.1.177 2-hydroxybenzoyl-coa sorbus aucuparia 0.037 0.02933 3 PMID:19757094 -2.3.1.177 benzoyl-coa malus domestica 0.283 0.209 2 PMID:29199980 -2.3.1.177 benzoyl-coa pyrus communis 0.055 0.045 2 PMID:27410389 -2.3.1.177 benzoyl-coa sorbus aucuparia 0.017 0.011015 4 PMID:17109150;PMID:19757094 -2.3.1.177 salicoyl-coa pyrus communis 0.89 0.8300000000000001 2 PMID:27410389 -2.3.1.179 lauroyl-coa escherichia coli 0.047 0.047 1 PMID:22017312 -2.3.1.179 malonyl-acp escherichia coli 0.029 0.029 1 PMID:22017312 -2.3.1.179 malonyl-coa escherichia coli 0.042 0.042 1 PMID:22017312 -2.3.1.179 malonyl-phosphopantetheine escherichia coli 0.022 0.022 1 PMID:22017312 -2.3.1.179 malonyl-phosphopantetheine-14-mer escherichia coli 0.023 0.023 1 PMID:22017312 -2.3.1.179 malonyl-phosphopantetheine-16-mer escherichia coli 0.022 0.022 1 PMID:22017312 -2.3.1.179 malonyl-phosphopantetheine-8-mer escherichia coli 0.018 0.018 1 PMID:22017312 -2.3.1.18 4-nitrophenyl alpha-d-galactopyranoside escherichia coli 1.42 1.42 1 PMID:7592843 -2.3.1.18 4-nitrophenyl-beta-d-galactopyranoside escherichia coli 11.1 11.1 1 PMID:17208523 -2.3.1.18 isopropyl-thio-beta-d-galactopyranoside escherichia coli 133.0 127.5 2 PMID:17208523 -2.3.1.18 o-nitrophenyl-beta-d-galactopyranoside escherichia coli 8.9 8.9 1 PMID:7592843 -2.3.1.18 p-nitrophenyl-beta-d-galactopyranoside escherichia coli 14.7 8.45 6 PMID:17208523;PMID:7592843 -2.3.1.18 p-nitrophenyl-beta-d-glucopyranoside escherichia coli 1.84 1.84 1 PMID:7592843 -2.3.1.18 p-nitrophenyl-beta-d-lactopyranoside escherichia coli 1.84 1.84 1 PMID:7592843 -2.3.1.18 phenyl-beta-d-galactopyranoside escherichia coli 13.0 13.0 1 PMID:7592843 -2.3.1.180 2-methylbutyryl-coa listeria monocytogenes 0.46 0.28250000000000003 2 PMID:19863661 -2.3.1.180 acetyl-coa listeria monocytogenes 0.0007 0.0007 1 PMID:19863661 -2.3.1.180 acetyl-coa staphylococcus aureus 7.2 3.13 3 PMID:11959561;PMID:15987898 -2.3.1.180 butyryl-coa staphylococcus aureus 41.6 3.8 3 PMID:11959561;PMID:15987898 -2.3.1.180 hexanoyl-coa staphylococcus aureus 41.7 24.900000000000002 2 PMID:15987898 -2.3.1.180 isobutyryl-coa listeria monocytogenes 0.32 0.211 2 PMID:19863661 -2.3.1.180 isobutyryl-coa staphylococcus aureus 47.1 24.365000000000002 2 PMID:11959561;PMID:15987898 -2.3.1.180 isovaleryl-coa listeria monocytogenes 0.12 0.06899999999999999 2 PMID:19863661 -2.3.1.180 isovaleryl-coa staphylococcus aureus 30.5 30.5 1 PMID:15987898 -2.3.1.181 apo-h protein escherichia coli 0.2 0.2 1 PMID:15642479 -2.3.1.181 octanoyl-[acyl-carrier protein] escherichia coli 0.2 0.2 1 PMID:15642479 -2.3.1.183 dl-phosphinothricin pseudomonas syringae pv. tomato 3.5 3.5 1 PMID:40054337 -2.3.1.183 l-methionine sulfone deinococcus radiodurans 11.0 11.0 1 PMID:27694229 -2.3.1.183 l-methionine sulfone geobacillus kaustophilus 1.0 1.0 1 PMID:27694229 -2.3.1.183 l-methionine sulfone pseudomonas aeruginosa 610.0 610.0 1 PMID:17253769 -2.3.1.183 l-methionine sulfoximine deinococcus radiodurans 11.0 11.0 1 PMID:27694229 -2.3.1.183 l-methionine sulfoximine geobacillus kaustophilus 1.0 1.0 1 PMID:27694229 -2.3.1.183 l-methionine sulfoximine pseudomonas aeruginosa 505.0 505.0 1 PMID:17253769 -2.3.1.183 l-methionine sulfoximine pseudomonas syringae pv. tomato 7.1 7.1 1 PMID:40054337 -2.3.1.183 l-methionine sulfoximine rhodococcus sp. (in: high g+c gram-positive bacteria) 0.5 0.5 1 * -2.3.1.183 l-phosphinothricin rhodococcus sp. (in: high g+c gram-positive bacteria) 2.18 2.18 1 * -2.3.1.183 phosphinothricin deinococcus radiodurans 5.0 5.0 1 PMID:27694229 -2.3.1.183 phosphinothricin enterobacteriaceae bacterium 1.2 1.2 1 PMID:37247996 -2.3.1.183 phosphinothricin geobacillus kaustophilus 1.0 1.0 1 PMID:27694229 -2.3.1.184 3-cyclopropylbutanoyl-[acp] mesorhizobium sp. ors 3359 0.001 0.001 1 PMID:32356962 -2.3.1.184 3-methylvaleryl-[acp] mesorhizobium sp. ors 3359 0.0019 0.0019 1 PMID:32356962 -2.3.1.184 4-coumaroyl-[acp] mesorhizobium sp. ors 3359 0.0017 0.0017 1 PMID:32356962 -2.3.1.184 4-methylvaleryl-[acp] mesorhizobium sp. ors 3359 0.0027 0.0027 1 PMID:32356962 -2.3.1.184 5-methylhexanoyl-[acp] mesorhizobium sp. ors 3359 0.0084 0.0084 1 PMID:32356962 -2.3.1.184 butanoyl-[acp] mesorhizobium sp. ors 3359 0.0099 0.0099 1 PMID:32356962 -2.3.1.184 butyryl-[acyl-carrier protein 1] pseudomonas aeruginosa 0.35 0.35 1 PMID:15723540 -2.3.1.184 butyryl-[acyl-carrier protein 2] pseudomonas aeruginosa 0.46 0.46 1 PMID:15723540 -2.3.1.184 butyryl-[acyl-carrier protein 3] pseudomonas aeruginosa 0.026 0.026 1 PMID:15723540 -2.3.1.184 butyryl-coa pseudomonas aeruginosa 0.05 0.05 1 PMID:15723540 -2.3.1.184 decanoyl-[acp] mesorhizobium sp. ors 3359 0.0011 0.0011 1 PMID:32356962 -2.3.1.184 hexanoyl-[acp] mesorhizobium sp. ors 3359 0.0093 0.0093 1 PMID:32356962 -2.3.1.184 hexanoyl-[acyl-carrier protein] serratia fonticola 4.433 4.433 1 PMID:38820426 -2.3.1.184 isobutanoyl-[acp] mesorhizobium sp. ors 3359 0.017 0.017 1 PMID:32356962 -2.3.1.184 isovaleryl-[acp] mesorhizobium sp. ors 3359 0.0022 0.0022 1 PMID:32356962 -2.3.1.184 lauroyl-[acp] mesorhizobium sp. ors 3359 0.0017 0.0017 1 PMID:32356962 -2.3.1.184 octanoyl-[acp] mesorhizobium sp. ors 3359 0.0048 0.0048 1 PMID:32356962 -2.3.1.19 2-ethylbutanoyl-coa listeria monocytogenes 100.9 100.9 2 PMID:27940001 -2.3.1.19 2-methylbutanoyl-coa listeria monocytogenes 849.1 849.1 2 PMID:27940001 -2.3.1.19 acetyl-coa listeria monocytogenes 302.4 302.4 2 PMID:27940001 -2.3.1.19 butanoyl-coa listeria monocytogenes 673.9 673.9 2 PMID:27940001 -2.3.1.19 hexanoyl-coa listeria monocytogenes 47.0 47.0 2 PMID:27940001 -2.3.1.19 isobutanoyl-coa listeria monocytogenes 1263.4 1263.4 2 PMID:27940001 -2.3.1.19 isovaleryl-coa listeria monocytogenes 1043.4 1043.4 2 PMID:27940001 -2.3.1.19 pentanoyl-coa listeria monocytogenes 676.1 676.1 2 PMID:27940001 -2.3.1.19 propionyl-coa listeria monocytogenes 518.8 518.8 2 PMID:27940001 -2.3.1.191 (3r)-3-hydroxymyristoyl-[acyl-carrier protein] escherichia coli 23.0 23.0 1 PMID:18422345 -2.3.1.191 udp-3-o-((3r)-3-hydroxymyristoyl)-alpha-d-glucosamine escherichia coli 23.0 23.0 1 PMID:18422345 -2.3.1.191 udp-3-o-[(3r)-3-hydroxymyristoyl]-alpha-d-glucosamine escherichia coli 3.0 3.0 1 PMID:22381368 -2.3.1.195 (3z)-hex-3-en-ol arabidopsis thaliana 11.3 11.3 1 PMID:17163881 -2.3.1.195 1-octanol arabidopsis thaliana 0.125 0.125 1 PMID:17163881 -2.3.1.195 acetyl-coa arabidopsis thaliana 23.0 23.0 1 PMID:17163881 -2.3.1.196 2-phenylethanol petunia x hybrida 35.8 35.8 1 PMID:15286288 -2.3.1.196 3-hydroxybenzyl alcohol populus trichocarpa 1.97 1.6949999999999998 2 PMID:25561400 -2.3.1.196 acetyl-coa clarkia breweri 21.5 21.5 1 PMID:12226525 -2.3.1.196 acetyl-coa petunia x hybrida 4.4 4.4 1 PMID:15286288 -2.3.1.196 acetyl-coa populus trichocarpa 0.43 0.375 2 PMID:25561400 -2.3.1.196 benzoyl-coa clarkia breweri 124.0 124.0 1 PMID:12226525 -2.3.1.196 benzoyl-coa petunia x hybrida 81.3 69.2 2 PMID:15286288 -2.3.1.196 benzoyl-coa populus trichocarpa 2.25 2.035 4 PMID:25561400 -2.3.1.196 benzoyl-coa vitis labrusca 0.045 0.045 2 PMID:16262710 -2.3.1.196 benzyl alcohol clarkia breweri 85.2 85.2 1 PMID:12226525 -2.3.1.196 benzyl alcohol petunia x hybrida 36.9 19.255 2 PMID:15286288 -2.3.1.196 benzyl alcohol populus trichocarpa 1.79 1.095 2 PMID:25561400 -2.3.1.196 cinnamoyl-coa clarkia breweri 0.9 0.9 1 PMID:12226525 -2.3.1.196 cinnamyl alcohol clarkia breweri 47.2 47.2 1 PMID:12226525 -2.3.1.196 salicyl alcohol populus trichocarpa 2.06 1.205 2 PMID:25561400 -2.3.1.197 acetyl-coa aneurinibacillus thermoaerophilus 3.1 3.1 1 PMID:12740380 -2.3.1.197 dtdp-3-amino-3,6-dideoxy-alpha-d-galactopyranose aneurinibacillus thermoaerophilus 2.3 2.3 1 PMID:12740380 -2.3.1.20 palmitoyl-coa mycobacterium tuberculosis 0.92 0.92 1 PMID:21819455 -2.3.1.201 udp-2-acetamido-3-amino-2,3-dideoxy-alpha-d-glucuronate pseudomonas aeruginosa 48.3 48.3 1 PMID:19348502 -2.3.1.203 udp-2-acetamido-4-amino-2,4,6-trideoxy-alpha-d-glucopyranose acinetobacter baumannii 510000.0 510000.0 1 PMID:24064219 -2.3.1.203 udp-2-acetamido-4-amino-2,4,6-trideoxy-alpha-d-glucopyranose neisseria gonorrhoeae 72000.0 72000.0 1 PMID:24064219 -2.3.1.203 udp-4-amino-4,6-dideoxy-n-acetyl-alpha-d-glucosamine campylobacter jejuni 8050.0 8050.0 1 PMID:17087520 -2.3.1.205 acetyl-coa aspergillus fumigatus 0.6 0.6 1 PMID:19672909 -2.3.1.205 fumigaclavine b aspergillus fumigatus 0.6 0.6 1 PMID:19672909 -2.3.1.206 butyryl-coa cannabis sativa 0.012 0.012 1 PMID:19454282 -2.3.1.206 hexanoyl-coa cannabis sativa 0.058 0.058 1 PMID:19454282 -2.3.1.208 2-hydroxybenzoyl-coa sorbus aucuparia 0.037 0.029 3 PMID:19757094 -2.3.1.209 acetyl-coa escherichia coli 21.6 21.6 1 PMID:17905981 -2.3.1.209 dtdp-4-amino-4,6-dideoxy-alpha-d-glucose escherichia coli 155.3 155.3 1 PMID:17905981 -2.3.1.21 l-carnitine homo sapiens 148.6 139.25 2 PMID:34063237 -2.3.1.21 palmitoyl-coa homo sapiens 145.3 145.0 2 PMID:34063237 -2.3.1.212 4-coumaroyl-coa rheum palmatum 0.0298 0.0298 1 PMID:11389739;PMID:12724310;PMID:17165930 -2.3.1.212 4-coumaroyl-coa rubus idaeus 0.011 0.010499999999999999 2 * -2.3.1.212 d-phenylalanyl-coa rheum palmatum 0.135 0.135 1 PMID:22645592 -2.3.1.212 l-phenylalanyl-coa rheum palmatum 0.463 0.463 1 PMID:22645592 -2.3.1.212 malonyl-coa rheum palmatum 0.0296 0.0296 1 PMID:12724310 -2.3.1.212 malonyl-coa rubus idaeus 0.008 0.00785 2 * -2.3.1.212 n-methylanthraniloyl-coa rheum palmatum 0.0247 0.0247 1 PMID:22645592 -2.3.1.214 4'''-demalonylsalvianin salvia splendens 0.55 0.55 1 PMID:15165190 -2.3.1.214 malonyl-coa salvia splendens 0.55 0.55 1 PMID:15165190 -2.3.1.215 acetyl-coa vitis vinifera 1.11 1.11 1 PMID:26395841 -2.3.1.215 caffeoyl-coa vitis vinifera 0.29 0.29 1 PMID:26395841 -2.3.1.215 coumaroyl-coa vitis vinifera 0.13 0.13 1 PMID:26395841 -2.3.1.215 cyanidin 3-o,5-o-beta-d-diglucoside vitis vinifera 0.18 0.18 1 PMID:26395841 -2.3.1.215 cyanidin 3-o-beta-d-glucoside vitis vinifera 77.0 77.0 1 PMID:26395841 -2.3.1.215 delphinidin 3-o-beta-d-glucoside vitis vinifera 67.89 67.89 1 PMID:26395841 -2.3.1.215 malonyl-coa vitis vinifera 0.92 0.92 1 PMID:26395841 -2.3.1.215 malvidin 3-o-beta-d-glucoside vitis vinifera 13.92 13.92 1 PMID:26395841 -2.3.1.215 peonidin 3-o-beta-d-glucoside vitis vinifera 14.2 14.2 1 PMID:26395841 -2.3.1.217 3-oxo-5-phenyl-4-pentenoic acid curcuma longa 0.125 0.125 1 PMID:21148316 -2.3.1.217 cinnamoyl-diketide-n-acetylcysteamine curcuma longa 0.0043 0.0043 1 PMID:21148316 -2.3.1.217 feruloyl-coa curcuma longa 0.0183 0.01255 4 PMID:19258320;PMID:19622354 -2.3.1.218 feruloyl-coa curcuma longa 0.02 0.02 1 PMID:19258320 -2.3.1.218 malonyl-coa curcuma longa 0.0112 0.0112 1 PMID:19258320 -2.3.1.219 4-coumaroyl-coa curcuma longa 3.15 0.01495 4 PMID:19258320;PMID:19622354 -2.3.1.220 benzoyl-coa garcinia mangostana 0.0495 0.0495 1 PMID:22390826 -2.3.1.220 benzoyl-coa hypericum androsaemum 0.055 0.0183 3 PMID:19710020;PMID:29199980 -2.3.1.220 benzoyl-coa hypericum perforatum 0.0046 0.0046 1 PMID:29210088 -2.3.1.220 malonyl-coa garcinia mangostana 0.0582 0.0582 1 PMID:22390826 -2.3.1.220 malonyl-coa hypericum androsaemum 0.055 0.055 1 PMID:19710020 -2.3.1.221 acetyl-[acyl-carrier protein] aspergillus parasiticus 0.0407 0.0407 1 PMID:22452347 -2.3.1.221 hexanoyl-[acyl-carrier protein] aspergillus parasiticus 0.0472 0.0472 1 PMID:22452347 -2.3.1.222 acetyl phosphate neomoorella thermoacetica 2.65 2.65 1 PMID:27338272 -2.3.1.222 acetyl phosphate salmonella enterica 5.4 5.4 1 PMID:17158662 -2.3.1.222 acetyl-coa neomoorella thermoacetica 5.18 2.69 4 PMID:27338272 -2.3.1.222 butanoyl-coa neomoorella thermoacetica 0.12 0.12 1 PMID:27338272 -2.3.1.222 butyryl-coa neomoorella thermoacetica 0.12 0.12 1 PMID:27338272 -2.3.1.222 propanoyl phosphate salmonella enterica 20.7 20.7 1 PMID:17158662 -2.3.1.222 propanoyl-coa neomoorella thermoacetica 1.14 0.6749999999999999 2 PMID:27338272 -2.3.1.222 propionyl-coa neomoorella thermoacetica 1.14 0.6749999999999999 2 PMID:27338272 -2.3.1.224 acetyl-coa jasminum sambac 316.8 171.25 2 PMID:35009018 -2.3.1.224 benzyl alcohol jasminum sambac 201.5 119.15 2 PMID:35009018 -2.3.1.224 malonyl-coa salvia splendens 0.76 0.655 2 PMID:15165190 -2.3.1.224 monodemalonylsalvianin salvia splendens 0.76 0.655 2 PMID:15165190 -2.3.1.226 (s)-1-pyrroline-5-carboxylate pectobacterium carotovorum 1.52 1.52 1 PMID:15595850 -2.3.1.226 malonyl-coa pectobacterium carotovorum 1.7 1.7 1 PMID:15595850 -2.3.1.228 isovaleryl-acp bradyrhizobium diazoefficiens 0.02 0.02 1 PMID:25401334 -2.3.1.228 isovaleryl-coa bradyrhizobium diazoefficiens 0.021 0.021 1 PMID:25401334 -2.3.1.23 docosahexanoyl-coa mus musculus 0.0132 0.00817 2 PMID:32204912 -2.3.1.230 2-aminobenzoyl-coa pseudomonas aeruginosa 0.0165 0.0165 1 PMID:23916145 -2.3.1.230 3-oxodecanoate pseudomonas aeruginosa 0.0165 0.0165 1 PMID:23916145 -2.3.1.232 anthraniloyl-coa vitis labrusca 0.022 0.016 2 PMID:16262710 -2.3.1.232 methanol vitis labrusca 0.0058 0.00465 2 PMID:16262710 -2.3.1.233 hexanoyl-coa streptomyces griseus 0.6 0.6 1 PMID:12139488 -2.3.1.233 malonyl-coa streptomyces coelicolor 45.7 0.022 3 PMID:12905073;PMID:15265863;PMID:17331946 -2.3.1.233 malonyl-coa streptomyces griseus 0.013 0.009 2 PMID:11723138;PMID:17331946 -2.3.1.233 malonyl-coa strongylocentrotus purpuratus 0.0057 0.0057 1 PMID:35588530 -2.3.1.238 (s)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] aspergillus terreus 0.806 0.806 1 PMID:19530726 -2.3.1.238 monacolin j acid aspergillus terreus 0.004 0.004 1 * -2.3.1.239 (e)-(2s,4r,8r,9r)-s-2-acetamidoethyl 9-hydroxy-2,4,8-trimethyl-5-oxoundec-6-enethioate streptomyces venezuelae 0.05 0.05 1 PMID:15941278 -2.3.1.240 (e)-(2s,4r,8r,9r)-s-2-acetamidoethyl 9-hydroxy-2,4,8-trimethyl-5-oxoundec-6-enethioate streptomyces venezuelae 0.055 0.055 1 PMID:15941278 -2.3.1.241 (3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->4)-(3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->6)-2-deoxy-2-[[(3r)-3-hydroxytetradecanoyl]amino]-3-o-[(3r)-3-hydroxytetradecanoyl]-4-o-phosphono-beta-d-glucopyranosyl-(1->6)-2-deoxy-3-o-[(3r)-3-hydroxytetradecanoyl]-2-[[(3r)-3-hydroxytetradecanoyl]amino]-1-o-phosphono-alpha-d-glucopyranose escherichia coli 131.0 131.0 1 PMID:18656959 -2.3.1.246 malonyl-coa amycolatopsis mediterranei 0.0135 0.0135 1 PMID:14744141 -2.3.1.247 (5s)-5-amino-3-oxohexanoate candidatus cloacimonas acidaminovorans 2.69 2.69 1 PMID:21632536 -2.3.1.247 acetyl-coa candidatus cloacimonas acidaminovorans 2.69 2.69 1 PMID:21632536 -2.3.1.248 coa arabidopsis thaliana 39.6 39.6 1 PMID:19168716 -2.3.1.248 n1,n8-bis(sinapoyl)-spermidine arabidopsis thaliana 37.8 37.8 1 PMID:19168716 -2.3.1.248 putrescine arabidopsis thaliana 0.3 0.3 1 PMID:19168716 -2.3.1.248 sinapoyl-coa arabidopsis thaliana 5.1 5.1 1 PMID:19168716 -2.3.1.248 spermidine arabidopsis thaliana 5.6 5.6 1 PMID:19168716 -2.3.1.249 4-coumaroyl-coa arabidopsis thaliana 3.4 3.4 1 PMID:19168716 -2.3.1.249 spermidine arabidopsis thaliana 3.1 3.1 1 PMID:19168716 -2.3.1.253 malonyl-coa pseudomonas fluorescens 0.4 0.17 3 PMID:15826166;PMID:16931521;PMID:18437267 -2.3.1.254 migpeeggrwgrpvgrrrrrpvrvyp homo sapiens 0.18 0.18 1 PMID:19744929 -2.3.1.254 mlalisrrwgrpvgrrrrrpvrvyp homo sapiens 0.11 0.11 1 PMID:19744929 -2.3.1.254 mldpeeggrwgrpvgrrrrrpvrvyp homo sapiens 0.12 0.12 1 PMID:19744929 -2.3.1.254 mlgpeggrwgrpvgrrrrrpvrvyp homo sapiens 0.12 0.12 1 PMID:19744929 -2.3.1.254 mlgteeggrwgrpvgrrrrrpvrvyp homo sapiens 0.093 0.093 1 PMID:19744929 -2.3.1.254 mlgtgparwgrpvgrrrrrpvrvyp homo sapiens 0.038 0.038 1 PMID:19744929 -2.3.1.255 acetyl-coa saccharolobus solfataricus 0.56 0.56 1 PMID:25728374 -2.3.1.255 saseagvrwgrpvgrrrrp schizosaccharomyces pombe 3.0 3.0 1 PMID:23912279 -2.3.1.256 mahlvgsrrr saccharomyces cerevisiae 5.1 5.1 1 PMID:33139728 -2.3.1.256 mehlvgsrrr saccharomyces cerevisiae 4.0 4.0 1 PMID:33139728 -2.3.1.256 mfalvgsrrr saccharomyces cerevisiae 6.9 6.9 1 PMID:33139728 -2.3.1.256 mfelvgsrrr saccharomyces cerevisiae 0.18 0.18 1 PMID:33139728 -2.3.1.256 mfhavgsrrr saccharomyces cerevisiae 8.0 8.0 1 PMID:33139728 -2.3.1.256 mfhevgsrrr saccharomyces cerevisiae 3.2 3.2 1 PMID:33139728 -2.3.1.256 mfhfvgsrrr saccharomyces cerevisiae 10.0 10.0 1 PMID:33139728 -2.3.1.256 mfhlegsrrr saccharomyces cerevisiae 6.7 6.7 1 PMID:33139728 -2.3.1.256 mfhlvgsrrr saccharomyces cerevisiae 4.2 4.2 1 PMID:33139728 -2.3.1.256 mfrlvgsrrr saccharomyces cerevisiae 9.0 9.0 1 PMID:33139728 -2.3.1.256 mkhlvgsrrr saccharomyces cerevisiae 0.35 0.35 1 PMID:33139728 -2.3.1.256 mlefvgsrrr saccharomyces cerevisiae 10.3 10.3 1 PMID:33139728 -2.3.1.256 mlhlvgsrrr saccharomyces cerevisiae 5.6 5.6 1 PMID:33139728 -2.3.1.256 mlrevgsrrr saccharomyces cerevisiae 1.01 1.01 1 PMID:33139728 -2.3.1.256 mlrfegsrrr saccharomyces cerevisiae 8.3 8.3 1 PMID:33139728 -2.3.1.256 mlrfvgsrrr saccharomyces cerevisiae 12.0 6.36 2 PMID:33139728 -2.3.1.256 mlrfvtkrwgrpvgrrrrp schizosaccharomyces pombe 19.7 19.7 1 PMID:34019809 -2.3.1.256 mrhlvgsrrr saccharomyces cerevisiae 0.135 0.135 1 PMID:33139728 -2.3.1.256 mwhlvgsrrr saccharomyces cerevisiae 3.4 3.4 1 PMID:33139728 -2.3.1.256 myhlvgsrrr saccharomyces cerevisiae 2.5 2.5 1 PMID:33139728 -2.3.1.256 n-terminal-l-methionyl-l-tryptanoyl-[arfp1 peptide] saccharomyces cerevisiae 3.2 3.2 1 PMID:33139728 -2.3.1.258 mass arabidopsis thaliana 0.26 0.26 1 PMID:33400917 -2.3.1.258 migperrr homo sapiens 0.18 0.18 1 PMID:19744929 -2.3.1.258 mlalirrr homo sapiens 0.11 0.11 1 PMID:19744929 -2.3.1.258 mldperrr homo sapiens 0.12 0.12 1 PMID:19744929 -2.3.1.258 mlgperrr homo sapiens 0.12 0.12 1 PMID:19744929 -2.3.1.258 mlgterrr homo sapiens 0.09 0.09 1 PMID:19744929 -2.3.1.258 mlgtgrrr homo sapiens 0.04 0.04 1 PMID:19744929 -2.3.1.258 mvnale neurospora crassa 1.598 1.598 1 PMID:36142717 -2.3.1.258 mvnale thermochaetoides thermophila 0.6067 0.3983 3 PMID:36142717 -2.3.1.258 n-terminal-l-methionyl-l-leucyl-glycyl-l-proline homo sapiens 0.0575 0.0545 2 PMID:32042062 -2.3.1.259 acetyl-coa arabidopsis thaliana 0.82 0.7135 2 PMID:32548857 -2.3.1.262 anthraniloyl-coa pseudomonas aeruginosa 0.3 0.3 1 PMID:19694421 -2.3.1.263 2-amino-4-oxopentanoate acetoanaerobium sticklandii 3.4 3.4 1 PMID:19251850 -2.3.1.263 coa acetoanaerobium sticklandii 3.5 3.5 1 PMID:19251850 -2.3.1.263 rac-2-amino-4-oxopentanoate pelosinus propionicus 7.36 7.36 1 PMID:35611954 -2.3.1.268 4-nitrophenyl acetate hanseniaspora uvarum 33.68 33.68 1 PMID:40062491 -2.3.1.268 4-nitrophenyl butyrate hanseniaspora uvarum 8.32 8.32 1 PMID:40062491 -2.3.1.268 4-nitrophenyl hexanoate hanseniaspora uvarum 0.79 0.79 1 PMID:40062491 -2.3.1.271 acetyl-coa saccharomyces cerevisiae 31.0 31.0 1 PMID:19170243 -2.3.1.271 azetidine-2-carboxylate saccharomyces cerevisiae 6.0 6.0 1 PMID:19170243 -2.3.1.271 cis-4-hydroxy-l-proline saccharomyces cerevisiae 5.19 5.19 1 PMID:22578594 -2.3.1.271 delta1-pyrroline-5-carboxylate saccharomyces cerevisiae 121.0 121.0 1 PMID:15308773 -2.3.1.271 l-azetidine-2-carboxylate saccharomyces cerevisiae 13.57 13.57 1 PMID:22578594 -2.3.1.271 l-azetidine-2-carboxylic acid saccharomyces cerevisiae 287.2 33.5 3 PMID:15308773;PMID:18373682;PMID:23818613 -2.3.1.273 2-o-(alpha-d-glucopyranosyl)-d-glycerate mycolicibacterium hassiacum 0.00033 0.00033 1 PMID:26324178 -2.3.1.273 2-o-(alpha-d-glucopyranosyl)-d-glycerate mycolicibacterium smegmatis 0.00033 0.00033 1 PMID:26324178 -2.3.1.273 2-o-[alpha-d-glucopyranosyl-(1->6)-alpha-d-glucopyranosyl]-d-glycerate mycolicibacterium hassiacum 0.0017 0.0010999999999999998 2 PMID:26324178 -2.3.1.273 2-o-[alpha-d-glucopyranosyl-(1->6)-alpha-d-glucopyranosyl]-d-glycerate mycolicibacterium smegmatis 0.038 0.038 1 PMID:26324178 -2.3.1.273 hexanoyl-coa mycolicibacterium hassiacum 0.00067 0.00042 2 PMID:26324178 -2.3.1.273 octanoyl-coa mycolicibacterium hassiacum 0.002 0.001085 2 PMID:26324178 -2.3.1.273 octanoyl-coa mycolicibacterium smegmatis 0.037 0.018664999999999998 2 PMID:26324178 -2.3.1.274 holo-[acyl-carrier protein] bacillus subtilis 2.467 2.467 1 PMID:32180316 -2.3.1.274 palmitoyl phosphate bacillus subtilis 2.783 2.783 1 PMID:32180316 -2.3.1.274 palmitoyl-[acyl-carrier protein] bacillus subtilis 0.00127 0.00127 1 PMID:32180316 -2.3.1.274 phosphate bacillus subtilis 0.0103 0.0103 1 PMID:32180316 -2.3.1.276 alpha-d-galactosamine 1-phosphate sulfurisphaera tokodaii 69.7 69.7 2 PMID:20400541;PMID:25567746 -2.3.1.277 glycerone phosphate streptomyces griseus 2.0 2.0 1 * -2.3.1.28 chloramphenicol staphylococcus aureus 209.0 206.0 2 PMID:25783628;PMID:31636704 -2.3.1.28 isobutanol staphylococcus aureus 0.3 0.3 1 PMID:31636704 -2.3.1.280 (aminomethyl)phosphonate salmonella enterica subsp. enterica serovar typhimurium 7.0 7.0 1 PMID:16503658 -2.3.1.280 (s)-1-aminoethylphosphonic acid salmonella enterica subsp. enterica serovar typhimurium 13.3 13.3 1 PMID:16503658 -2.3.1.280 1-aminobutyl phosphonic acid salmonella enterica subsp. enterica serovar typhimurium 1.0 1.0 1 PMID:16503658 -2.3.1.280 1-aminopropyl phosphonic acid salmonella enterica subsp. enterica serovar typhimurium 7.4 7.4 1 PMID:16503658 -2.3.1.280 2-aminoethanesulfinic acid salmonella enterica subsp. enterica serovar typhimurium 20.0 20.0 1 PMID:16503658 -2.3.1.280 2-aminoethanesulfonic acid salmonella enterica subsp. enterica serovar typhimurium 14.8 14.8 1 PMID:16503658 -2.3.1.280 2-aminoethyl phosphonic acid salmonella enterica subsp. enterica serovar typhimurium 9.0 9.0 1 PMID:16503658 -2.3.1.280 3-aminopropyl phosphonic acid salmonella enterica subsp. enterica serovar typhimurium 5.4 5.4 1 PMID:16503658 -2.3.1.280 4-aminobutylphosphonic acid salmonella enterica subsp. enterica serovar typhimurium 0.5 0.5 1 PMID:16503658 -2.3.1.280 acetyl-coa salmonella enterica subsp. enterica serovar typhimurium 13.1 13.1 1 PMID:16503658 -2.3.1.280 malonyl-coa salmonella enterica subsp. enterica serovar typhimurium 0.4 0.4 1 PMID:16503658 -2.3.1.280 propionyl-coa salmonella enterica subsp. enterica serovar typhimurium 14.7 14.7 1 PMID:16503658 -2.3.1.282 octan-1-ol mycobacterium tuberculosis 0.0004 0.0004 1 PMID:15070765 -2.3.1.282 palmitoyl-coa mycobacterium tuberculosis 0.00045 0.00045 1 PMID:15070765 -2.3.1.286 [histone h3]-n6-acetyl-l-lysine plasmodium falciparum 0.00025 0.00025 1 PMID:18729382 -2.3.1.286 [histone h3]-n6-acetyl-l-lysine9 homo sapiens 0.275 0.275 1 PMID:25704306 -2.3.1.286 [histone h3]-n6-acetyl-l-lysine9 plasmodium falciparum 0.001 0.001 1 PMID:21992006 -2.3.1.286 [histone h3]-n6-butyryl-l-lysine9 plasmodium falciparum 0.001 0.001 1 PMID:21992006 -2.3.1.286 [histone h3]-n6-myristoyl-l-lysine9 homo sapiens 0.018 0.018 1 PMID:25704306 -2.3.1.286 [histone h3]-n6-myristoyl-l-lysine9 plasmodium falciparum 0.01 0.01 1 PMID:21992006 -2.3.1.286 [histone h3]-n6-octanoyl-l-lysine9 plasmodium falciparum 0.001 0.001 1 PMID:21992006 -2.3.1.286 [histone h4]-n6-acetyl-l-lysine plasmodium falciparum 0.00035 0.00035 1 PMID:18729382 -2.3.1.286 [peptide p300]-n6-acetyl-l-lysine plasmodium falciparum 0.00092 0.00092 1 PMID:18729382 -2.3.1.286 k382azakac-containing p53 peptide thermotoga maritima 0.023 0.023 1 PMID:22352831 -2.3.1.286 k382kac-containing p53 peptide thermotoga maritima 0.18 0.18 1 PMID:22352831 -2.3.1.288 2-o-sulfo-alpha,alpha-trehalose mycobacterium tuberculosis 0.0067 0.0067 1 PMID:17592143 -2.3.1.288 palmitoyl-coa mycobacterium tuberculosis 0.0032 0.0032 1 PMID:17592143 -2.3.1.292 (s)-methylmalonyl-coa mycobacterium tuberculosis 0.22 0.22 1 PMID:15749014 -2.3.1.293 c20:0-[acyl-carrier protein from escherichia coli] mycobacterium tuberculosis 0.075 0.075 1 PMID:11600501 -2.3.1.293 malonyl-[acyl-carrier protein from escherichia coli] mycobacterium tuberculosis 0.08 0.08 1 PMID:11600501 -2.3.1.293 palmitoyl-[acyl-carrier protein acpm] mycobacterium tuberculosis 0.533 0.533 1 PMID:20018879 -2.3.1.293 palmitoyl-[acyl-carrier protein from escherichia coli] mycobacterium tuberculosis 0.088 0.088 1 PMID:11600501 -2.3.1.294 c20:0-[acyl-carrier protein from escherichia coli] mycobacterium tuberculosis 0.01 0.01 1 PMID:11600501 -2.3.1.294 malonyl-[acyl-carrier protein from escherichia coli] mycobacterium tuberculosis 0.023 0.023 1 PMID:11600501 -2.3.1.294 malonyl-coa escherichia coli 0.042 0.042 1 PMID:22017312 -2.3.1.294 malonyl-phosphopantetheine escherichia coli 0.022 0.022 1 PMID:22017312 -2.3.1.294 malonyl-phosphopantetheine 14-mer escherichia coli 0.023 0.023 1 PMID:22017312 -2.3.1.294 malonyl-phosphopantetheine 16-mer escherichia coli 0.022 0.022 1 PMID:22017312 -2.3.1.294 malonyl-phosphopantetheine 8-mer escherichia coli 0.018 0.018 1 PMID:22017312 -2.3.1.294 palmitoyl-[acyl-carrier protein from escherichia coli] mycobacterium tuberculosis 0.027 0.027 1 PMID:11600501 -2.3.1.3 acetyl-coa clostridium acetobutylicum 2.5 2.5 1 PMID:27348258 -2.3.1.30 acetyl-coa entamoeba histolytica 117.9 58.63 3 PMID:18851994 -2.3.1.30 acetyl-coa escherichia coli 0.068 0.068 1 PMID:12627979 -2.3.1.30 acetyl-coa mycobacterium tuberculosis 3.4 0.05 3 PMID:32976971;PMID:34090964;PMID:38311199 -2.3.1.30 acetyl-coa neisseria gonorrhoeae 1176.0 1176.0 1 PMID:34890451 -2.3.1.30 acetyl-coa salmonella enterica subsp. enterica serovar typhimurium 200.0 126.065 2 PMID:32435386;PMID:6986825 -2.3.1.30 acetyl-coa staphylococcus aureus 1.683 1.683 1 PMID:30974158 -2.3.1.30 acetyl-coa thermus thermophilus hb8 0.54 0.54 1 PMID:15632302 -2.3.1.30 l-serine entamoeba histolytica 43.83 25.52 3 PMID:18851994 -2.3.1.30 l-serine mycobacterium tuberculosis 59.6 14.2 5 PMID:32976971;PMID:34090964;PMID:38311199 -2.3.1.30 l-serine neisseria gonorrhoeae 1444.0 1444.0 1 PMID:34890451 -2.3.1.30 l-serine salmonella enterica subsp. enterica serovar typhimurium 63.55 63.55 1 PMID:32435386 -2.3.1.30 l-serine staphylococcus aureus 1.36 1.36 1 PMID:30974158 -2.3.1.30 l-serine streptomyces lavendulae 1.58 1.58 1 PMID:23396912 -2.3.1.30 l-serine thermus thermophilus hb8 0.48 0.48 1 PMID:15632302 -2.3.1.300 (2s)-2-methylbutanoyl-coa listeria monocytogenes serotype 1/2a 0.46 0.2535 2 PMID:19863661 -2.3.1.300 isobutanoyl-coa listeria monocytogenes serotype 1/2a 0.32 0.211 2 PMID:19863661 -2.3.1.300 isobutanoyl-coa streptomyces coelicolor 0.286 0.1485 2 PMID:22136753 -2.3.1.300 isovaleryl-coa listeria monocytogenes serotype 1/2a 0.12 0.06899999999999999 2 PMID:19863661 -2.3.1.300 malonyl-[fabc] streptomyces coelicolor 0.338 0.338 1 PMID:22136753 -2.3.1.300 malonyl-[redq] streptomyces coelicolor 0.019 0.019 1 PMID:22136753 -2.3.1.302 caffeoyl-coa trifolium pratense 10.2 10.2 1 PMID:29606213 -2.3.1.302 l-tyrosine trifolium pratense 9.1 9.1 1 PMID:29606213 -2.3.1.304 (3r)-3-hydroxyacyl-coa brevundimonas sp. kh11j01 12.0 12.0 1 PMID:35533829 -2.3.1.304 (r)-3-hydroxybutanoyl-coa allochromatium vinosum 508.0 508.0 1 PMID:26974339 -2.3.1.304 (r)-3-hydroxybutanoyl-coa caulobacter vibrioides 75.0 75.0 1 PMID:26974339 -2.3.1.304 (r)-3-hydroxybutanoyl-coa cupriavidus necator 196.0 196.0 1 PMID:24896226 -2.3.1.304 (r)-3-hydroxybutyryl-coa allochromatium vinosum 65.33 42.0 2 PMID:11566031 -2.3.1.304 (r)-3-hydroxybutyryl-coa cupriavidus necator 44.0 44.0 1 PMID:15768438 -2.3.1.304 (r)-3-hydroxybutyryl-coa ectothiorhodospira shaposhnikovii 320.0 320.0 2 PMID:14715006 -2.3.1.304 (r)-3-hydroxypentanoyl-coa allochromatium vinosum 8.0 4.715 2 PMID:11566031 -2.3.1.304 (r)-3-hydroxyvaleryl-coa allochromatium vinosum 98.1 98.1 1 PMID:26974339 -2.3.1.304 (r)-3-hydroxyvaleryl-coa caulobacter vibrioides 14.4 14.4 1 PMID:26974339 -2.3.1.304 (r)-3-hydroxyvaleryl-coa ectothiorhodospira shaposhnikovii 122.0 122.0 2 PMID:14715006 -2.3.1.304 (r,s)-3-hydroxybutyryl-coa aeromonas caviae 4.33 4.33 1 PMID:33748082 -2.3.1.304 (r,s)-3-hydroxyhexanoyl-coa aeromonas caviae 2.55 2.55 1 PMID:33748082 -2.3.1.304 3-(r)-hydroxhex-5-enoyl-coa allochromatium vinosum 12.7 12.7 1 PMID:26974339 -2.3.1.304 3-(r)-hydroxhex-5-enoyl-coa caulobacter vibrioides 0.06 0.06 1 PMID:26974339 -2.3.1.304 3-(r)-hydroxyhex5-ynoyl-coa allochromatium vinosum 2.99 2.99 1 PMID:26974339 -2.3.1.304 3-(r)-hydroxyhex5-ynoyl-coa caulobacter vibrioides 0.13 0.13 1 PMID:26974339 -2.3.1.304 3-(s)-hydroxy-4-azidobutyryl-coa allochromatium vinosum 20.0 20.0 1 PMID:26974339 -2.3.1.304 3-(s)-hydroxy-4-azidobutyryl-coa caulobacter vibrioides 0.19 0.19 1 PMID:26974339 -2.3.1.304 3-hydroxypropionyl-coa cupriavidus necator 10.0 10.0 1 PMID:11710134 -2.3.1.304 4-hydroxybutyryl-coa ectothiorhodospira shaposhnikovii 297.0 297.0 2 PMID:14715006 -2.3.1.31 3-amino-1-propanol haemophilus influenzae 5.0 5.0 1 PMID:10913262 -2.3.1.31 4-hydroxybutyric acid haemophilus influenzae 50.0 50.0 1 PMID:10913262 -2.3.1.31 4-nitrophenyl acetate haemophilus influenzae 7.8 7.8 1 PMID:10913262 -2.3.1.31 4-nitrophenyl acetate mycobacterium tuberculosis 0.21 0.21 1 PMID:32976971 -2.3.1.31 acetyl-coa bacillus cereus 0.98 0.328 11 PMID:18216013 -2.3.1.31 acetyl-coa candida albicans 15.2 15.1 2 PMID:35887110 -2.3.1.31 acetyl-coa haemophilus influenzae 92.0 92.0 1 PMID:10913262 -2.3.1.31 acetyl-coa mycobacterium tuberculosis 0.54 0.54 3 PMID:32976971;PMID:34090964 -2.3.1.31 acetyl-coa mycolicibacterium smegmatis 3.074 3.074 1 PMID:31378370 -2.3.1.31 acetyl-coa schizosaccharomyces pombe 9.34 9.34 1 PMID:16216079 -2.3.1.31 acetyl-coa thermotoga maritima 23.0 23.0 1 PMID:16708165 -2.3.1.31 beta-hydroxybutyryl-coa thermotoga maritima 0.12 0.12 1 PMID:16708165 -2.3.1.31 butyryl-coa haemophilus influenzae 27.0 27.0 1 PMID:10913262 -2.3.1.31 butyryl-coa schizosaccharomyces pombe 47.2 47.2 1 PMID:16216079 -2.3.1.31 coa thermotoga maritima 1.9 1.9 1 PMID:16708165 -2.3.1.31 crotonyl-coa haemophilus influenzae 15.0 15.0 1 PMID:10913262 -2.3.1.31 d-homoserine haemophilus influenzae 78.0 78.0 1 PMID:10913262 -2.3.1.31 d-homoserine thermotoga maritima 16.0 16.0 1 PMID:16708165 -2.3.1.31 glutaryl-coa thermotoga maritima 0.25 0.25 1 PMID:16708165 -2.3.1.31 isobutyryl-coa thermotoga maritima 0.19 0.19 1 PMID:16708165 -2.3.1.31 l-homoserine candida albicans 13.1 13.05 2 PMID:35887110 -2.3.1.31 l-homoserine cryptococcus neoformans 122.0 122.0 1 PMID:17353245 -2.3.1.31 l-homoserine haemophilus influenzae 92.0 92.0 1 PMID:10913262 -2.3.1.31 l-homoserine mycobacterium tuberculosis 0.52 0.52 3 PMID:32976971;PMID:34090964 -2.3.1.31 l-homoserine mycolicibacterium smegmatis 2.918 2.918 1 PMID:31378370 -2.3.1.31 l-homoserine schizosaccharomyces pombe 9.6 9.6 1 PMID:16216079 -2.3.1.31 l-homoserine streptomyces lavendulae 1.47 1.47 1 PMID:23396912 -2.3.1.31 l-homoserine thermotoga maritima 23.0 23.0 1 PMID:16708165 -2.3.1.31 malonyl-coa thermotoga maritima 0.12 0.12 1 PMID:16708165 -2.3.1.31 o-acetyl-l-homoserine haemophilus influenzae 31.0 31.0 1 PMID:10913262 -2.3.1.31 o-acetylhomoserine thermotoga maritima 1.9 1.9 1 PMID:16708165 -2.3.1.31 p-nitrophenylacetate mycobacterium tuberculosis 0.21 0.21 1 PMID:32976971 -2.3.1.31 propionyl-coa haemophilus influenzae 30.0 30.0 1 PMID:10913262 -2.3.1.31 propionyl-coa schizosaccharomyces pombe 16.1 16.1 1 PMID:16216079 -2.3.1.31 propionyl-coa thermotoga maritima 2.6 2.6 1 PMID:16708165 -2.3.1.31 succinyl-coa bacillus cereus 0.803 0.803 1 PMID:18216013 -2.3.1.31 succinyl-coa thermotoga maritima 0.19 0.19 1 PMID:16708165 -2.3.1.313 [dihydrolipoyllysine acetyltransferase]-n6-[(r)-lipoyl]-l-lysine259 mus musculus 0.0018 0.0018 1 PMID:25525879 -2.3.1.313 [histone h3]-n6-acetyl-l-lysine mus musculus 0.0005 0.0005 1 PMID:25525879 -2.3.1.313 [histone h3]-n6-biotinyl-l-lysine mus musculus 0.0019 0.0019 1 PMID:25525879 -2.3.1.32 acetyl-coa salmonella enterica 4.3 4.3 1 PMID:22010215 -2.3.1.32 acs (amp forming) salmonella enterica 8.0 8.0 1 PMID:22010215 -2.3.1.331 acetyl-coa chryseobacterium sp. 5-3b 16.2 16.2 1 PMID:28721586 -2.3.1.331 l-2-chlorophenylglycine chryseobacterium sp. 7.31 7.31 1 PMID:24375143 -2.3.1.331 l-2-phenylglycine chryseobacterium sp. 13.6 13.6 1 PMID:24375143 -2.3.1.331 l-2-phenylglycine chryseobacterium sp. 5-3b 6.3 6.3 1 PMID:28721586 -2.3.1.331 l-2-phenylglycine methyl ester chryseobacterium sp. 19.2 19.2 1 PMID:24375143 -2.3.1.333 malonyl-coa atropa belladonna 10.0 10.0 1 PMID:30538251 -2.3.1.333 n-methyl-delta1-pyrrolinium atropa belladonna 12.3 12.3 1 PMID:30538251 -2.3.1.334 benzoyl-coa erythroxylum coca 7.6 7.6 1 * -2.3.1.334 cinnamoyl-coa erythroxylum coca 46.0 46.0 1 * -2.3.1.334 ecgonine methyl ester erythroxylum coca 19.0 14.35 2 * -2.3.1.37 2-hydroxybutanoyl-coa mus musculus 0.067 0.067 1 PMID:19562746 -2.3.1.37 butanoyl-coa mus musculus 0.105 0.105 1 PMID:19562746 -2.3.1.37 glutaryl-coa mus musculus 0.117 0.117 1 PMID:19562746 -2.3.1.37 glycine caulobacter vibrioides 1.73 1.73 1 PMID:30242198 -2.3.1.37 glycine cereibacter sphaeroides 63.4 1.1 5 PMID:29027286;PMID:30232811 -2.3.1.37 glycine escherichia coli 0.02 0.02 1 PMID:20194506 -2.3.1.37 glycine homo sapiens 192.0 186.0 2 PMID:32499479 -2.3.1.37 glycine mus musculus 0.92 0.1665 6 PMID:15840827;PMID:19917609;PMID:21600186;PMID:26854603 -2.3.1.37 glycine rhodobacter capsulatus 2.78 2.78 1 PMID:39772634 -2.3.1.37 octanoyl-coa mus musculus 0.34 0.34 1 PMID:19562746 -2.3.1.37 succinyl-coa caulobacter vibrioides 1.73 1.73 1 PMID:30242198 -2.3.1.37 succinyl-coa cereibacter sphaeroides 1.3 1.08 4 PMID:30232811 -2.3.1.37 succinyl-coa homo sapiens 192.0 186.0 2 PMID:32499479 -2.3.1.37 succinyl-coa mus musculus 0.658 0.167 7 PMID:19562746;PMID:26511319;PMID:26605136;PMID:8416963;PMID:8916896;PMID:9250998;PMID:9484217;PMID:9521672;PMID:9605326 -2.3.1.37 succinyl-coa rhodobacter capsulatus 2.78 2.78 1 PMID:39772634 -2.3.1.37 succinyl-coa rhodopseudomonas palustris 2.74 2.74 1 PMID:30498972 -2.3.1.38 acetyl-coa rattus norvegicus 1.9 1.9 1 PMID:9115261 -2.3.1.38 acetyl-coa streptomyces collinus 0.0508 0.03665 2 PMID:11570897 -2.3.1.39 malonyl coa escherichia coli 1580.0 1580.0 1 PMID:11814333 -2.3.1.39 malonyl coa rattus norvegicus 1.2 1.2 1 PMID:9115261 -2.3.1.39 malonyl coa streptomyces coelicolor 450.0 435.0 2 PMID:11814333 -2.3.1.39 malonyl-coa escherichia coli 2100.0 2100.0 3 PMID:19462023;PMID:29075826 -2.3.1.39 malonyl-coa streptomyces coelicolor 100.0 100.0 1 PMID:12974642 -2.3.1.39 methylmalonyl-coa escherichia coli 1000.0 1000.0 2 PMID:29075826 -2.3.1.39 n-acetylcysteamine streptomyces coelicolor 0.00683 0.00683 1 PMID:11591161 -2.3.1.4 acetyl-coa plasmodium falciparum 10.31 10.31 1 PMID:33082260 -2.3.1.4 d-glucosamine 6-phosphate aspergillus fumigatus 38.0 38.0 1 PMID:18601654 -2.3.1.4 d-glucosamine 6-phosphate caenorhabditis elegans 136.0 136.0 1 PMID:30609921 -2.3.1.4 d-glucosamine 6-phosphate homo sapiens 22.1 15.55 2 PMID:18601654;PMID:18675810 -2.3.1.4 glucosamine 6-phosphate aspergillus fumigatus 38.0 38.0 1 PMID:18005663 -2.3.1.41 butanoyl-[acyl-carrier protein] homo sapiens 91.2 91.2 1 PMID:15668256 -2.3.1.41 butyryl-[acyl-carrier protein] plasmodium falciparum 1.32 1.32 1 PMID:16467310 -2.3.1.41 c10-[acyl-carrier protein] plasmodium falciparum 3.07 3.07 1 PMID:16467310 -2.3.1.41 c12-[acyl-carrier protein] plasmodium falciparum 0.69 0.69 1 PMID:16467310 -2.3.1.41 c14-[acyl-carrier protein] plasmodium falciparum 1.28 1.28 1 PMID:16467310 -2.3.1.41 c4-[acyl-carrier protein] plasmodium falciparum 1.32 1.32 1 PMID:16467310 -2.3.1.41 c6-[acyl-carrier protein] plasmodium falciparum 0.96 0.96 1 PMID:16467310 -2.3.1.41 c8-[acyl-carrier protein] plasmodium falciparum 1.63 1.63 1 PMID:16467310 -2.3.1.41 decanoyl-[acyl-carrier protein] homo sapiens 551.0 551.0 1 PMID:15668256 -2.3.1.41 decanoyl-[acyl-carrier protein] plasmodium falciparum 3.07 3.07 1 PMID:16467310 -2.3.1.41 dodecanoyl-[acyl-carrier protein] homo sapiens 303.0 303.0 1 PMID:15668256 -2.3.1.41 dodecanoyl-[acyl-carrier protein] plasmodium falciparum 0.69 0.69 1 PMID:16467310 -2.3.1.41 hexanoyl-[acyl-carrier protein] homo sapiens 353.0 353.0 1 PMID:15668256 -2.3.1.41 hexanoyl-[acyl-carrier protein] plasmodium falciparum 0.96 0.96 1 PMID:16467310 -2.3.1.41 lauroyl-acp escherichia coli 0.057 0.045 2 PMID:22017312 -2.3.1.41 lauroyl-coa escherichia coli 0.073 0.073 1 PMID:22017312 -2.3.1.41 malonyl-acp escherichia coli 0.011 0.011 1 PMID:22017312 -2.3.1.41 malonyl-acp mycobacterium tuberculosis 0.47 0.47 1 PMID:22017312 -2.3.1.41 malonyl-coa escherichia coli 0.12 0.12 1 PMID:22017312 -2.3.1.41 malonyl-coa mycobacterium tuberculosis 0.35 0.35 1 PMID:22017312 -2.3.1.41 malonyl-phosphopantetheine-14-mer escherichia coli 0.04 0.04 1 PMID:22017312 -2.3.1.41 malonyl-phosphopantetheine-14-mer mycobacterium tuberculosis 0.38 0.38 1 PMID:22017312 -2.3.1.41 malonyl-phosphopantetheine-16-mer escherichia coli 0.11 0.11 1 PMID:22017312 -2.3.1.41 malonyl-phosphopantetheine-16-mer mycobacterium tuberculosis 0.3 0.3 1 PMID:22017312 -2.3.1.41 malonyl-phosphopantetheine-8-mer escherichia coli 0.018 0.018 1 PMID:22017312 -2.3.1.41 malonyl-phosphopantetheine-8-mer mycobacterium tuberculosis 0.35 0.35 1 PMID:22017312 -2.3.1.41 myristoyl-[acyl-carrier protein] homo sapiens 6.0 6.0 1 PMID:15668256 -2.3.1.41 octanoyl-[acyl-carrier protein] homo sapiens 66.0 66.0 1 PMID:15668256 -2.3.1.41 octanoyl-[acyl-carrier protein] plasmodium falciparum 1.63 1.63 1 PMID:16467310 -2.3.1.41 palmitoyl-coa mycobacterium tuberculosis 0.08 0.08 1 PMID:22017312 -2.3.1.41 tetradecanoyl-[acyl-carrier protein] plasmodium falciparum 1.28 1.28 1 PMID:16467310 -2.3.1.46 coenzyme a escherichia coli 5.23 5.23 1 PMID:10572016 -2.3.1.46 d-homoserine escherichia coli 12.0 12.0 1 PMID:10572016 -2.3.1.46 glutaryl-coa escherichia coli 1.6 1.6 1 PMID:10572016 -2.3.1.46 l-homoserine escherichia coli 130.0 30.36 4 PMID:10572016;PMID:17302437;PMID:23898868;PMID:35084172 -2.3.1.46 l-homoserine mycobacterium tuberculosis 0.06 0.06 2 PMID:32976971;PMID:34090964 -2.3.1.46 o-succinyl-l-homoserine escherichia coli 5.23 5.23 1 PMID:10572016 -2.3.1.46 succinyl-coa escherichia coli 130.0 25.7 5 PMID:10572016;PMID:17302437;PMID:17442255;PMID:23898868;PMID:35084172 -2.3.1.46 succinyl-coa mycobacterium tuberculosis 0.06 0.06 2 PMID:32976971;PMID:34090964 -2.3.1.47 d-alanine mycobacterium tuberculosis 0.0036 0.0036 1 PMID:16769720 -2.3.1.47 l-alanine arabidopsis thaliana 0.11 0.11 1 PMID:16299174 -2.3.1.47 l-alanine escherichia coli 0.06 0.044 2 PMID:21600186 -2.3.1.47 l-alanine mycobacterium tuberculosis 0.007 0.007 1 PMID:16769720 -2.3.1.47 pimeloyl-coa arabidopsis thaliana 0.1 0.1 1 PMID:16299174 -2.3.1.47 pimeloyl-coa escherichia coli 0.001 0.0009165 2 PMID:10642176;PMID:9765987 -2.3.1.47 pimeloyl-coa lysinibacillus sphaericus 0.5 0.2525 2 PMID:1575677;PMID:8617279 -2.3.1.47 pimeloyl-coa mycobacterium tuberculosis 0.004 0.004 1 PMID:16769720 -2.3.1.48 3-azidopropionyl-coa homo sapiens 0.233 0.11900000000000001 2 PMID:28426192 -2.3.1.48 4-pentynoyl-coa homo sapiens 0.0067 0.0067 1 PMID:28426192 -2.3.1.48 acetyl-coa homo sapiens 4.14 0.033299999999999996 12 PMID:10777508;PMID:10811654;PMID:11009610;PMID:11397810;PMID:11994311;PMID:22615379;PMID:26505788;PMID:28426192 -2.3.1.48 acetyl-coa saccharomyces cerevisiae 1.6 0.11 9 PMID:10811654;PMID:11397810;PMID:11994311;PMID:17223684;PMID:20560668;PMID:21057107 -2.3.1.48 acetyl-coa sus scrofa 12.0 6.4 2 PMID:2303486 -2.3.1.48 acetyl-coa tetrahymena thermophila 0.0267 0.0267 1 PMID:11994311 -2.3.1.48 gga-((e)-4,5-dehydro)k-rhrkvlrdniq homo sapiens 0.089 0.089 1 PMID:33467728 -2.3.1.48 gga-(n6-amino)k-rhrkvlrdniq homo sapiens 0.207 0.207 1 PMID:33467728 -2.3.1.48 gga-betak-rhrkvlrdniq homo sapiens 0.037 0.037 1 PMID:33467728 -2.3.1.48 ggakrhrkvlrdniq homo sapiens 0.25 0.25 1 PMID:33467728 -2.3.1.48 histone saccharomyces cerevisiae 1.7 0.13 5 PMID:19056256 -2.3.1.48 histone sus scrofa 12.0 6.4 2 PMID:2303486 -2.3.1.48 histone h3 saccharomyces cerevisiae 0.62 0.62 1 PMID:20560668 -2.3.1.48 histone h3 tetrahymena thermophila 0.0267 0.0267 1 PMID:11994311 -2.3.1.48 histone h3 tail peptide saccharomyces cerevisiae 0.11 0.11 1 PMID:20560668 -2.3.1.48 histone h3-peptide homo sapiens 0.0667 0.0383 6 PMID:10777508;PMID:10811654;PMID:11009610;PMID:11397810;PMID:11994311 -2.3.1.48 histone h3-peptide saccharomyces cerevisiae 0.0283 0.0283 1 PMID:10811654;PMID:11397810;PMID:11994311 -2.3.1.48 histone h3-peptide p19 homo sapiens 0.131 0.131 1 PMID:11112280 -2.3.1.48 histone h3-peptide p20 homo sapiens 0.0583 0.0583 1 PMID:12391296 -2.3.1.48 histone h3-peptide p27 homo sapiens 0.17 0.17 1 PMID:11112280 -2.3.1.48 histone h4 peptide homo sapiens 4.28 4.28 1 PMID:22615379 -2.3.1.48 histone peptide saccharomyces cerevisiae 4.1 4.1 1 PMID:19056256 -2.3.1.5 2,3-dimethylaniline homo sapiens 256.0 141.5 2 PMID:17672512 -2.3.1.5 2,4-dimethylaniline homo sapiens 661.0 364.0 2 PMID:17672512 -2.3.1.5 2,5-dimethylaniline homo sapiens 313.0 159.35 2 PMID:17672512 -2.3.1.5 2-amino-4-chlorophenol mycobacterium tuberculosis 21.0 21.0 1 PMID:18795795 -2.3.1.5 2-amino-4-chlorophenol streptomyces griseus 0.27 0.27 1 PMID:17158669 -2.3.1.5 2-amino-4-methylphenol mycobacterium tuberculosis 70.0 70.0 1 PMID:18795795 -2.3.1.5 2-amino-4-methylphenol streptomyces griseus 1.3 1.3 1 PMID:17158669 -2.3.1.5 2-aminofluorene bacillus anthracis 0.43 0.43 1 PMID:27846346 -2.3.1.5 2-aminofluorene bacillus cereus 67.4 67.4 1 PMID:23770703 -2.3.1.5 2-aminofluorene homo sapiens 759.0 604.0 2 PMID:17672512 -2.3.1.5 2-aminofluorene mycobacteroides abscessus 199.0 199.0 1 PMID:25372695 -2.3.1.5 2-aminophenol mycobacterium tuberculosis 51.0 51.0 1 PMID:18795795 -2.3.1.5 2-aminophenol streptomyces griseus 0.41 0.41 1 PMID:17158669 -2.3.1.5 2-ethylaniline homo sapiens 61.0 61.0 1 PMID:17672512 -2.3.1.5 2-methylaniline homo sapiens 111.0 61.5 2 PMID:17672512 -2.3.1.5 2-toluidine homo sapiens 72.0 39.15 2 PMID:16959263 -2.3.1.5 2-toluidine mesocricetus auratus 4.8 4.8 1 PMID:16959263 -2.3.1.5 3,4-dichloroaniline mycobacteroides abscessus 8.0 8.0 1 PMID:25372695 -2.3.1.5 3,4-dimethylaniline homo sapiens 800.0 630.5 2 PMID:17672512 -2.3.1.5 3,5-dimethylaniline homo sapiens 1220.0 764.0 2 PMID:17672512 -2.3.1.5 3-amino-4-hydroxybenzaldehyde streptomyces griseus 0.29 0.29 1 PMID:17158669 -2.3.1.5 3-amino-4-hydroxybenzenesulfonic acid streptomyces griseus 1.1 1.1 1 PMID:17158669 -2.3.1.5 3-amino-4-hydroxybenzoic acid mycobacterium tuberculosis 94.0 94.0 1 PMID:18795795 -2.3.1.5 3-amino-4-hydroxybenzoic acid streptomyces griseus 1.3 1.3 1 PMID:17158669 -2.3.1.5 3-ethylaniline homo sapiens 1960.0 1135.0 2 PMID:17672512 -2.3.1.5 4-amino-3-hydroxybenzoic acid mycobacterium tuberculosis 66.0 66.0 1 PMID:18795795 -2.3.1.5 4-amino-3-methylbenzoic acid homo sapiens 16.6 8.950000000000001 2 PMID:16959263 -2.3.1.5 4-amino-3-methylbenzoic acid mesocricetus auratus 14.2 14.2 1 PMID:16959263 -2.3.1.5 4-aminobenzoic acid homo sapiens 127.0 74.0 2 PMID:16959263 -2.3.1.5 4-aminobenzoic acid mesocricetus auratus 620.0 265.0 7 PMID:16101314;PMID:16857211;PMID:16959263;PMID:19860825 -2.3.1.5 4-aminobenzoyl glutamic acid mesocricetus auratus 120.0 120.0 3 PMID:16101314;PMID:19860825 -2.3.1.5 4-aminobiphenyl homo sapiens 256.0 249.5 2 PMID:17672512 -2.3.1.5 4-aminosalicylate bacillus anthracis 0.6 0.6 1 PMID:27846346 -2.3.1.5 4-aminosalicylate mesorhizobium japonicum 1.36 1.36 1 PMID:32089267 -2.3.1.5 4-aminosalicylate mycobacteroides abscessus 1.0 1.0 1 PMID:25372695 -2.3.1.5 4-aminosalicylate vibrio vulnificus 0.482 0.482 1 PMID:33537010 -2.3.1.5 4-aminosalicylic acid bacillus cereus 56.6 56.6 1 PMID:23770703 -2.3.1.5 4-anisidine mycobacterium marinum 5.2 0.6 3 PMID:19636684 -2.3.1.5 4-anisidine mycobacterium tuberculosis 0.6 0.44999999999999996 2 PMID:19636684 -2.3.1.5 4-anisidine mycolicibacterium smegmatis 0.03 0.03 1 PMID:12628650 -2.3.1.5 4-bromoaniline mycolicibacterium smegmatis 0.0086 0.0086 1 PMID:12628650 -2.3.1.5 4-butoxyaniline mycobacteroides abscessus 112.0 112.0 1 PMID:25372695 -2.3.1.5 4-butoxyaniline mycolicibacterium smegmatis 0.039 0.039 1 PMID:12628650 -2.3.1.5 4-chloro-3-methylaniline vibrio vulnificus 0.449 0.449 1 PMID:33537010 -2.3.1.5 4-chloroaniline mycobacterium tuberculosis 0.2 0.2 1 PMID:18795795 -2.3.1.5 4-chloroaniline mycolicibacterium smegmatis 0.0069 0.0069 1 PMID:12628650 -2.3.1.5 4-ethoxyaniline mycolicibacterium smegmatis 0.036 0.036 1 PMID:12628650 -2.3.1.5 4-ethylaniline homo sapiens 700.0 565.0 2 PMID:17672512 -2.3.1.5 4-ethylaniline oryctolagus cuniculus 25.0 25.0 1 PMID:2897358 -2.3.1.5 4-fluoroaniline mycobacterium tuberculosis 0.9 0.9 1 PMID:18795795 -2.3.1.5 4-hydroxybenzhydrazide mycobacterium tuberculosis 10.9 10.9 1 PMID:18795795 -2.3.1.5 4-iodoaniline mycobacteroides abscessus 71.0 71.0 1 PMID:25372695 -2.3.1.5 4-iodoaniline mycolicibacterium smegmatis 0.0098 0.0098 1 PMID:12628650 -2.3.1.5 4-methylaniline homo sapiens 1600.0 951.5 2 PMID:17672512 -2.3.1.5 4-methylaniline mycobacterium tuberculosis 0.8 0.8 1 PMID:18795795 -2.3.1.5 4-nitroaniline mesocricetus auratus 0.6 0.6 2 PMID:16101314;PMID:19860825 -2.3.1.5 4-nitrophenyl acetate mesocricetus auratus 1301.0 620.0 3 PMID:16857211;PMID:19860825 -2.3.1.5 5-aminosalicylate mycobacteroides abscessus 47.0 47.0 1 PMID:25372695 -2.3.1.5 5-aminosalicylate mycolicibacterium smegmatis 0.044 0.044 1 PMID:12628650 -2.3.1.5 5-aminosalicylic acid mycobacterium marinum 5.2 1.8 3 PMID:19636684 -2.3.1.5 5-aminosalicylic acid mycobacterium tuberculosis 1.8 1.8 3 PMID:19636684 -2.3.1.5 5-aminosalicylic acid pseudomonas aeruginosa 434.0 434.0 1 PMID:17374145 -2.3.1.5 acetyl-coa bacillus cereus 19.3 19.3 1 PMID:23770703 -2.3.1.5 acetyl-coa fusarium verticillioides 1593.6 797.9499999999999 2 PMID:36178468 -2.3.1.5 acetyl-coa tsukamurella paurometabola 19.2 19.2 1 PMID:31673919 -2.3.1.5 aniline homo sapiens 711.0 496.0 2 PMID:17672512 -2.3.1.5 aniline mycobacterium tuberculosis 0.28 0.28 1 PMID:18795795 -2.3.1.5 anisidine mesocricetus auratus 260.0 260.0 2 PMID:16101314;PMID:19860825 -2.3.1.5 anisidine mycobacterium tuberculosis 2.9 2.9 1 PMID:18795795 -2.3.1.5 benzoic acid hydrazide mycobacterium tuberculosis 1.9 1.9 1 PMID:18795795 -2.3.1.5 hydralazine bacillus anthracis 0.63 0.63 1 PMID:27846346 -2.3.1.5 hydralazine mycobacterium tuberculosis 44.0 44.0 1 PMID:18795795 -2.3.1.5 hydralazine mycobacteroides abscessus 168.0 168.0 1 PMID:25372695 -2.3.1.5 hydralazine mycolicibacterium smegmatis 0.063 0.063 1 PMID:12628650 -2.3.1.5 hydralazine vibrio vulnificus 1.417 1.417 1 PMID:33537010 -2.3.1.5 isoniazid bacillus anthracis 0.51 0.51 1 PMID:27846346 -2.3.1.5 isoniazid bacillus cereus 289.3 289.3 1 PMID:23770703 -2.3.1.5 isoniazid mycobacterium marinum 1.7 0.3 3 PMID:19636684 -2.3.1.5 isoniazid mycobacterium tuberculosis 4.9 0.3 3 PMID:18795795;PMID:19636684 -2.3.1.5 isoniazid mycobacteroides abscessus 9.0 9.0 1 PMID:25372695 -2.3.1.5 isoniazid vibrio vulnificus 1.099 1.099 1 PMID:33537010 -2.3.1.5 malonyl-coa fusarium verticillioides 12.3 10.600000000000001 2 PMID:36178468 -2.3.1.5 malonyl-coa tsukamurella paurometabola 9.7 9.7 1 PMID:31673919 -2.3.1.5 nicotinic acid hydrazide mycobacterium tuberculosis 0.6 0.6 1 PMID:18795795 -2.3.1.5 p-aminobenzoic acid homo sapiens 298.0 168.0 2 PMID:17672512 -2.3.1.5 p-aminobenzoic acid mycobacterium tuberculosis 0.7 0.7 1 PMID:18795795 -2.3.1.5 p-aminosalicylic acid homo sapiens 591.0 309.0 2 PMID:17672512 -2.3.1.5 propionyl-coa fusarium verticillioides 838.1 419.65000000000003 2 PMID:36178468 -2.3.1.5 sulfamethazine homo sapiens 387.0 387.0 1 PMID:17672512 -2.3.1.50 caproyl-coa sphingomonas paucimobilis 0.034 0.034 1 PMID:32423667 -2.3.1.50 glycine sphingobacterium multivorum 0.0013 0.0013 1 PMID:37030501 -2.3.1.50 l-alanine sphingobacterium multivorum 0.007 0.007 1 PMID:37030501 -2.3.1.50 l-homoserine sphingobacterium multivorum 0.075 0.075 1 PMID:37030501 -2.3.1.50 l-serine sphingobacterium multivorum 0.217 0.217 1 PMID:37030501 -2.3.1.50 l-serine sphingomonas paucimobilis 1.54 1.15 3 PMID:19376777;PMID:23814788;PMID:24175284 -2.3.1.50 lauroyl-coa sphingomonas paucimobilis 0.11 0.11 1 PMID:32423667 -2.3.1.50 myristoyl-coa sphingomonas paucimobilis 0.76 0.76 1 PMID:32423667 -2.3.1.50 palmitoyl-coa bacteriovorax stolpii 0.03 0.03 1 PMID:17557831 -2.3.1.50 palmitoyl-coa rhizorhabdus wittichii 0.0687 0.0687 1 PMID:20578000 -2.3.1.50 palmitoyl-coa sphingobacterium multivorum 0.12 0.12 1 PMID:17557831 -2.3.1.50 palmitoyl-coa sphingobacterium spiritivorum 0.15 0.15 1 PMID:17557831 -2.3.1.50 palmitoyl-coa sphingomonas paucimobilis 1.15 0.85 5 PMID:11279212;PMID:19376777;PMID:24175284;PMID:32423667 -2.3.1.50 stearoyl-coa rhizorhabdus wittichii 0.083 0.083 1 PMID:20578000 -2.3.1.51 1-acyl-sn-glycerol 3-phosphate mycobacterium tuberculosis 0.238 0.2025 2 PMID:38676355 -2.3.1.51 oleoyl-coa mycobacterium tuberculosis 0.218 0.218 1 PMID:38676355 -2.3.1.51 pamitoleoyl-coa mycobacterium tuberculosis 0.175 0.175 1 PMID:38676355 -2.3.1.54 coa escherichia coli 225.0 165.0 2 PMID:34801558;PMID:37797332 -2.3.1.54 formate escherichia coli 4.33 4.0649999999999995 2 PMID:4615902 -2.3.1.54 pyruvate escherichia coli 225.0 12.8 3 PMID:37797332;PMID:4615902 -2.3.1.57 acetyl-coa bacillus subtilis 0.365 0.365 1 PMID:16210326 -2.3.1.57 acetyl-coa staphylococcus aureus 390.0 280.0 2 PMID:37508494 -2.3.1.57 acetyl-coa streptomyces sp. 0.858 0.858 1 PMID:22313365 -2.3.1.57 aminopropylcadaverine bacillus subtilis 0.1 0.1 1 PMID:16210326 -2.3.1.57 d-glucosamine 6-phosphate streptomyces sp. 1.358 1.358 1 PMID:22313365 -2.3.1.57 n1-acetylspermine bacillus subtilis 0.12 0.12 1 PMID:16210326 -2.3.1.57 poly-l-lysine streptomyces sp. 3.953 3.953 1 PMID:22313365 -2.3.1.57 spermidine bacillus subtilis 0.087 0.087 1 PMID:16210326 -2.3.1.57 spermidine bacillus thuringiensis 70.6 70.6 1 PMID:32283314 -2.3.1.57 spermidine cricetulus griseus 8.7 8.7 1 PMID:12578836 -2.3.1.57 spermidine enterococcus faecalis 1.58 1.58 1 PMID:30281855 -2.3.1.57 spermidine homo sapiens 9.73 9.73 1 PMID:39823891 -2.3.1.57 spermidine pseudomonas aeruginosa 0.21 0.21 1 PMID:39826527 -2.3.1.57 spermidine staphylococcus aureus 110.0 3.0 3 PMID:30281855;PMID:37508494 -2.3.1.57 spermidine streptomyces sp. 0.922 0.922 1 PMID:22313365 -2.3.1.57 spermine bacillus subtilis 0.32 0.32 1 PMID:16210326 -2.3.1.57 spermine bacillus thuringiensis 153.0 153.0 1 PMID:32283314 -2.3.1.57 spermine cricetulus griseus 5.0 5.0 1 PMID:12578836 -2.3.1.57 spermine cryptosporidium parvum 9.0 9.0 1 PMID:17289169 -2.3.1.57 spermine enterococcus faecalis 9.21 9.21 1 PMID:30281855 -2.3.1.57 spermine homo sapiens 2.58 2.58 1 PMID:39823891 -2.3.1.57 spermine staphylococcus aureus 420.0 5.3 3 PMID:30281855;PMID:37508494 -2.3.1.57 spermine streptomyces sp. 1.86 1.86 1 PMID:22313365 -2.3.1.57 spermine vibrio cholerae serotype o1 15.5 15.5 1 PMID:33928120 -2.3.1.59 acetyl-coa mycolicibacterium smegmatis 0.34 0.34 1 PMID:33299080 -2.3.1.59 gentamicin mycolicibacterium smegmatis 0.28 0.28 1 PMID:33299080 -2.3.1.59 kanamycin mycolicibacterium smegmatis 0.13 0.13 1 PMID:33299080 -2.3.1.59 neomycin mycolicibacterium smegmatis 0.1 0.1 1 PMID:33299080 -2.3.1.59 paromomycin mycolicibacterium smegmatis 1.08 1.08 1 PMID:33299080 -2.3.1.59 sisomicin mycolicibacterium smegmatis 1.87 1.87 1 PMID:33299080 -2.3.1.59 tobramycin mycolicibacterium smegmatis 3.34 3.34 1 PMID:33299080 -2.3.1.60 n3'-acetylgentamicin c1a escherichia coli 3.57 3.57 1 PMID:764855 -2.3.1.61 dl-dihydrolipoamide yarrowia lipolytica 186.0 186.0 1 PMID:26428234 -2.3.1.64 4-coumaroyl-coa hordeum murinum 1.33 1.33 1 PMID:34119689 -2.3.1.64 4-coumaroyl-coa hordeum vulgare 51.0 27.865000000000002 2 PMID:34119689 -2.3.1.64 4-coumaroyl-coa oryza sativa japonica group 0.013 0.013 1 PMID:34119689 -2.3.1.64 4-coumaroyl-coa triticum aestivum 9.43 6.325 2 PMID:34119689 -2.3.1.64 agmatine hordeum murinum 6.4 6.4 1 PMID:34119689 -2.3.1.64 agmatine hordeum vulgare 54.5 29.21 2 PMID:34119689 -2.3.1.64 agmatine triticum aestivum 19.8 16.0 2 PMID:34119689 -2.3.1.64 caffeoyl-coa hordeum murinum 13.1 13.1 1 PMID:34119689 -2.3.1.64 caffeoyl-coa hordeum vulgare 20.1 14.445 2 PMID:34119689 -2.3.1.64 caffeoyl-coa oryza sativa japonica group 0.008 0.008 1 PMID:34119689 -2.3.1.64 caffeoyl-coa triticum aestivum 10.0 8.14 2 PMID:34119689 -2.3.1.64 cinnamoyl-coa hordeum murinum 24.1 24.1 1 PMID:34119689 -2.3.1.64 cinnamoyl-coa hordeum vulgare 110.0 65.95 2 PMID:34119689 -2.3.1.64 cinnamoyl-coa oryza sativa japonica group 0.023 0.023 1 PMID:34119689 -2.3.1.64 cinnamoyl-coa triticum aestivum 16.9 16.6 2 PMID:34119689 -2.3.1.64 feruloyl-coa hordeum murinum 18.1 18.1 1 PMID:34119689 -2.3.1.64 feruloyl-coa hordeum vulgare 34.0 25.35 2 PMID:34119689 -2.3.1.64 feruloyl-coa oryza sativa japonica group 0.01 0.01 1 PMID:34119689 -2.3.1.64 feruloyl-coa triticum aestivum 22.7 15.614999999999998 2 PMID:34119689 -2.3.1.7 acetyl-coa columba livia 568.0 568.0 1 PMID:32710884 -2.3.1.7 acetyl-coa homo sapiens 38.5 38.5 1 PMID:15099582 -2.3.1.7 acetyl-coa mus musculus 97.6 48.919999999999995 2 PMID:16870616 -2.3.1.7 carnitine columba livia 568.0 568.0 1 PMID:32710884 -2.3.1.7 carnitine rattus norvegicus 86.9 86.9 1 PMID:16681386 -2.3.1.7 choline rattus norvegicus 1.58 1.58 1 PMID:16681386 -2.3.1.7 coa columba livia 376.0 376.0 1 PMID:32710884 -2.3.1.7 hexanoyl-coa mus musculus 30.4 30.4 1 PMID:16870616 -2.3.1.7 o-acetylcarnitine columba livia 376.0 376.0 1 PMID:32710884 -2.3.1.71 benzoyl-coa mus musculus 4.2 4.2 1 PMID:24576660 -2.3.1.71 glycine mus musculus 3.2 3.2 1 PMID:24576660 -2.3.1.71 glycine ethyl ester mus musculus 0.57 0.57 1 PMID:24576660 -2.3.1.71 glycine methyl ester mus musculus 1.0 1.0 1 PMID:24576660 -2.3.1.74 4-coumaroyl-coa antirrhinum majus 1.27 0.6785 2 PMID:32054839 -2.3.1.74 4-coumaroyl-coa glycine max 0.0617 0.0617 1 PMID:38735137 -2.3.1.74 4-coumaroyl-coa hypericum androsaemum 0.042 0.042 1 PMID:12795704 -2.3.1.74 4-coumaroyl-coa malus domestica 0.0202 0.0201 2 PMID:29199980 -2.3.1.74 4-coumaroyl-coa oryza sativa japonica group 0.000862 0.000555 2 PMID:32471084 -2.3.1.74 4-coumaroyl-coa panicum virgatum 3.04 0.11274999999999999 4 PMID:38891840 -2.3.1.74 4-coumaroyl-coa polygonum cuspidatum 0.11 0.11 1 PMID:27419064 -2.3.1.74 4-coumaroyl-coa rubus idaeus 0.045 0.045 2 * -2.3.1.74 4-coumaroyl-coa scutellaria baicalensis 0.021 0.01885 2 PMID:11112437;PMID:15381408 -2.3.1.74 4-coumaroyl-coa styphnolobium japonicum 0.065 0.065 1 PMID:38662928 -2.3.1.74 benzoyl-coa hypericum androsaemum 0.0113 0.0113 1 PMID:12795704 -2.3.1.74 decanoyl-coa scutellaria baicalensis 0.044 0.044 1 PMID:15381408 -2.3.1.74 hexanoyl-coa scutellaria baicalensis 0.147 0.147 1 PMID:15381408 -2.3.1.74 malonyl-coa antirrhinum majus 0.59 0.365 2 PMID:32054839 -2.3.1.74 malonyl-coa polygonum cuspidatum 0.082 0.082 1 PMID:27419064 -2.3.1.74 malonyl-coa rubus idaeus 0.071 0.071 2 * -2.3.1.74 malonyl-coa styphnolobium japonicum 0.12 0.12 1 PMID:38662928 -2.3.1.74 octanoyl-coa scutellaria baicalensis 0.066 0.066 1 PMID:15381408 -2.3.1.75 arachidonoyl-coa thraustochytrium roseum 0.165 0.08990000000000001 4 PMID:28725265 -2.3.1.75 decanoyl-coa thraustochytrium roseum 0.0941 0.0154 4 PMID:28725265 -2.3.1.75 eicosapentaenoyl-coa thraustochytrium roseum 0.498 0.2547 4 PMID:28725265 -2.3.1.75 hexadecanol marinobacter nauticus 4794.0 4794.0 1 PMID:17351040 -2.3.1.75 lauroyl-coa thraustochytrium roseum 0.243 0.1316 4 PMID:28725265 -2.3.1.75 myristoyl-coa thraustochytrium roseum 0.331 0.1782 4 PMID:28725265 -2.3.1.75 octadecatrienoyl-coa thraustochytrium roseum 0.242 0.1328 4 PMID:28725265 -2.3.1.75 octanoyl-coa thraustochytrium roseum 0.102 0.06025 4 PMID:28725265 -2.3.1.75 palmitoyl-coa thraustochytrium roseum 0.341 0.1865 4 PMID:28725265 -2.3.1.75 stearoyl-coa thraustochytrium roseum 0.604 0.32095 4 PMID:28725265 -2.3.1.8 acetyl phosphate escherichia coli 415.0 321.0 2 PMID:20236319;PMID:21046341 -2.3.1.8 acetyl phosphate methanosarcina thermophila 5190.0 784.25 4 PMID:16428419;PMID:9401029 -2.3.1.8 acetyl phosphate neomoorella thermoacetica 2.65 2.65 1 PMID:27338272 -2.3.1.8 acetyl phosphate salmonella enterica 1927.0 1250.75 2 PMID:14996820;PMID:17339319 -2.3.1.8 acetyl-coa escherichia coli 120.0 74.8 2 PMID:20236319;PMID:21046341 -2.3.1.8 acetyl-coa methanosarcina thermophila 4500.0 4500.0 1 PMID:12876371 -2.3.1.8 acetyl-coa neomoorella thermoacetica 5.18 2.69 2 PMID:27338272 -2.3.1.8 acetyl-coa porphyromonas gingivalis 1487.0 1487.0 1 PMID:31007866 -2.3.1.8 acetyl-coa salmonella enterica 83.1 42.415 2 PMID:17339319 -2.3.1.8 coa methanosarcina thermophila 5190.0 87.5 5 PMID:11418565;PMID:16428418;PMID:16428419;PMID:9401029 -2.3.1.8 coa salmonella enterica 574.5 574.5 1 PMID:17339319 -2.3.1.8 desulfo-coa methanosarcina thermophila 4.53 4.53 1 PMID:11418565 -2.3.1.8 phosphate methanosarcina thermophila 1500.0 1500.0 1 PMID:16428419 -2.3.1.8 propionyl-coa neomoorella thermoacetica 0.21 0.21 1 PMID:27338272 -2.3.1.81 acetyl-coa corynebacterium striatum 0.24 0.24 2 PMID:26149994 -2.3.1.81 acetyl-coa escherichia coli 39.0 39.0 1 PMID:16331988 -2.3.1.81 acetyl-coa mycobacteroides abscessus 2.2 2.2 1 PMID:31254444 -2.3.1.81 acetyl-coa pseudomonas aeruginosa 39.4 24.95 2 PMID:20387904 -2.3.1.81 amikacin escherichia coli 0.5 0.136 4 PMID:16331988;PMID:19899089 -2.3.1.81 apramycin escherichia coli 61.0 61.0 1 PMID:16331988 -2.3.1.81 butirosin escherichia coli 3.5 3.5 1 PMID:16331988 -2.3.1.81 butyryl-coa escherichia coli 0.3 0.3 1 PMID:16331988 -2.3.1.81 dibekacin corynebacterium striatum 0.17 0.17 2 PMID:26149994 -2.3.1.81 gentamicin escherichia coli 0.182 0.123 3 PMID:19899089 -2.3.1.81 gentamicin pseudomonas aeruginosa 6.12 6.12 1 PMID:35921328 -2.3.1.81 gentamicin c1 enterobacter cloacae 9.7 9.7 1 PMID:28316100 -2.3.1.81 gentamicin c2 enterobacter cloacae 18.4 18.4 1 PMID:28316100 -2.3.1.81 gentamycin escherichia coli 40.0 40.0 1 PMID:16331988 -2.3.1.81 kanamycin pseudomonas aeruginosa 4.45 4.45 1 PMID:35921328 -2.3.1.81 kanamycin a escherichia coli 80.0 0.144 9 PMID:16331988;PMID:19899089 -2.3.1.81 kanamycin a pseudomonas aeruginosa 51.4 51.2 2 PMID:20387903;PMID:24320996 -2.3.1.81 kanamycin b corynebacterium striatum 0.23 0.23 2 PMID:26149994 -2.3.1.81 kanamycin b enterobacter cloacae 14.5 14.5 1 PMID:28316100 -2.3.1.81 kanamycin b pseudomonas aeruginosa 55.0 54.75 2 PMID:20387903;PMID:24320996 -2.3.1.81 lividomycin a pseudomonas aeruginosa 33.8 33.8 1 PMID:20387903 -2.3.1.81 malonyl-coa escherichia coli 9.0 9.0 1 PMID:16331988 -2.3.1.81 malonyl-coa pseudomonas aeruginosa 5.7 5.7 1 PMID:20387904 -2.3.1.81 n-propionyl-coa pseudomonas aeruginosa 10.2 10.2 1 PMID:20387904 -2.3.1.81 neomicin pseudomonas aeruginosa 6.15 6.15 1 PMID:35921328 -2.3.1.81 neomycin escherichia coli 60.0 60.0 1 PMID:16331988 -2.3.1.81 neomycin pseudomonas aeruginosa 10.0 10.0 1 PMID:24320996 -2.3.1.81 neomycin b escherichia coli 0.188 0.132 2 PMID:19899089 -2.3.1.81 neomycin b pseudomonas aeruginosa 9.5 9.5 1 PMID:20387903 -2.3.1.81 neomycin e pseudomonas aeruginosa 34.0 34.0 1 PMID:24320996 -2.3.1.81 netilmicin escherichia coli 32.0 32.0 1 PMID:16331988 -2.3.1.81 paromomycin escherichia coli 15.0 15.0 1 PMID:16331988 -2.3.1.81 paromomycin pseudomonas aeruginosa 33.6 19.560000000000002 2 PMID:20387903;PMID:35921328 -2.3.1.81 propionyl-coa escherichia coli 33.0 33.0 1 PMID:16331988 -2.3.1.81 ribostamycin escherichia coli 146.0 146.0 1 PMID:16331988 -2.3.1.81 ribostamycin pseudomonas aeruginosa 24.0 23.5 3 PMID:20387903;PMID:24320996;PMID:35921328 -2.3.1.81 sisomicin enterobacter cloacae 24.5 24.5 1 PMID:28316100 -2.3.1.81 sisomicin escherichia coli 0.173 0.147 2 PMID:19899089 -2.3.1.81 sisomicin pseudomonas aeruginosa 10.48 10.48 1 PMID:35921328 -2.3.1.81 sisomycin escherichia coli 51.0 51.0 1 PMID:16331988 -2.3.1.81 sisomycin pseudomonas aeruginosa 46.3 46.15 2 PMID:20387903;PMID:24320996 -2.3.1.81 tobramycin enterobacter cloacae 43.5 43.5 1 PMID:28316100 -2.3.1.81 tobramycin escherichia coli 162.0 0.179 3 PMID:16331988;PMID:19899089 -2.3.1.81 tobramycin pseudomonas aeruginosa 48.0 47.8 3 PMID:20387903;PMID:24320996;PMID:35921328 -2.3.1.82 2'-n-ethyl netilmicin acinetobacter baumannii 0.098 0.098 1 PMID:27785912 -2.3.1.82 2'-n-ethylnetilmicin acinetobacter haemolyticus 0.097 0.097 1 PMID:27785912 -2.3.1.82 acetyl-coa enterococcus faecium 1.61 0.403 4 PMID:12767240;PMID:14717599;PMID:18295586;PMID:9145851 -2.3.1.82 acetyl-coa enterococcus sp. 1.2 1.2 1 PMID:12566434 -2.3.1.82 acetyl-coa escherichia coli 5.23 2.32 3 PMID:18710261 -2.3.1.82 acetyl-coa pseudomonas aeruginosa 1.0 1.0 1 PMID:17417880 -2.3.1.82 acetyl-coa serratia marcescens 12.1 1.62 3 PMID:16819836;PMID:23485681 -2.3.1.82 acetyl-coa uncultured bacterium 1.51 1.51 1 PMID:28756664 -2.3.1.82 amikacin acinetobacter baumannii 0.496 0.496 1 PMID:27785912 -2.3.1.82 amikacin acinetobacter haemolyticus 0.328 0.328 1 PMID:27785912 -2.3.1.82 amikacin enterococcus faecium 0.29 0.11 3 PMID:14717599;PMID:18295586;PMID:9145851 -2.3.1.82 amikacin pseudomonas aeruginosa 3.5 3.5 1 PMID:17417880 -2.3.1.82 amikacin serratia marcescens 7.09 1.56 4 PMID:16819836;PMID:23485681;PMID:26270859 -2.3.1.82 amikacin stenotrophomonas maltophilia 0.11 0.11 1 PMID:25092711 -2.3.1.82 arbekacin acinetobacter baumannii 0.021 0.021 1 PMID:27785912 -2.3.1.82 arbekacin acinetobacter haemolyticus 0.077 0.077 1 PMID:27785912 -2.3.1.82 arbekacin serratia marcescens 17.0 17.0 1 PMID:26270859 -2.3.1.82 arbekacin stenotrophomonas maltophilia 0.57 0.57 1 PMID:25092711 -2.3.1.82 butirosin enterococcus faecium 0.466 0.466 1 PMID:9145851 -2.3.1.82 butirosin a acinetobacter baumannii 0.113 0.113 1 PMID:27785912 -2.3.1.82 butirosin a acinetobacter haemolyticus 0.107 0.107 1 PMID:27785912 -2.3.1.82 ciprofloxacin escherichia coli 1.03 1.03 1 PMID:18710261 -2.3.1.82 dibekacin acinetobacter baumannii 0.04 0.04 1 PMID:27785912 -2.3.1.82 dibekacin acinetobacter haemolyticus 0.127 0.127 1 PMID:27785912 -2.3.1.82 dibekacin enterococcus faecium 0.632 0.632 1 PMID:9145851 -2.3.1.82 dibekacin pseudomonas aeruginosa 1.3 1.3 1 PMID:17417880 -2.3.1.82 dibekacin serratia marcescens 85.0 85.0 1 PMID:26270859 -2.3.1.82 dibekacin stenotrophomonas maltophilia 0.25 0.25 1 PMID:25092711 -2.3.1.82 fortimicin a enterococcus sp. 0.28 0.28 1 PMID:12566434 -2.3.1.82 gentamicin acinetobacter baumannii 0.016 0.016 1 PMID:27785912 -2.3.1.82 gentamicin acinetobacter haemolyticus 0.055 0.055 1 PMID:27785912 -2.3.1.82 gentamicin aeromonas hydrophila 0.16 0.16 1 PMID:37920263 -2.3.1.82 gentamicin pseudomonas aeruginosa 2.0 2.0 1 PMID:17417880 -2.3.1.82 gentamicin serratia marcescens 3.33 1.11 3 PMID:16819836;PMID:23485681 -2.3.1.82 gentamicin b enterococcus faecium 0.388 0.388 1 PMID:9145851 -2.3.1.82 gentamicin c enterococcus faecium 1.01 1.01 1 PMID:18295586 -2.3.1.82 gentamycin uncultured bacterium 1.17 1.17 1 PMID:28756664 -2.3.1.82 isepamicin acinetobacter baumannii 0.62 0.62 1 PMID:27785912 -2.3.1.82 isepamicin acinetobacter haemolyticus 0.779 0.779 1 PMID:27785912 -2.3.1.82 isepamicin pseudomonas aeruginosa 2.4 2.4 1 PMID:17417880 -2.3.1.82 isepamicin serratia marcescens 25.0 25.0 1 PMID:26270859 -2.3.1.82 isepamicin stenotrophomonas maltophilia 0.05 0.05 1 PMID:25092711 -2.3.1.82 kanamycin aeromonas hydrophila 1.22 1.22 1 PMID:37920263 -2.3.1.82 kanamycin serratia marcescens 10.0 3.81 3 PMID:23485681;PMID:26270859 -2.3.1.82 kanamycin stenotrophomonas maltophilia 0.04 0.04 1 PMID:25092711 -2.3.1.82 kanamycin uncultured bacterium 0.207 0.207 1 PMID:28756664 -2.3.1.82 kanamycin a enterococcus faecium 1.68 0.818 4 PMID:12767240;PMID:14717599;PMID:18295586;PMID:9145851 -2.3.1.82 kanamycin a enterococcus sp. 1.7 1.7 1 PMID:12566434 -2.3.1.82 kanamycin a pseudomonas aeruginosa 2.4 2.4 1 PMID:17417880 -2.3.1.82 kanamycin a serratia marcescens 0.8 0.8 1 PMID:16819836 -2.3.1.82 kanamycin b acinetobacter baumannii 0.06 0.06 1 PMID:27785912 -2.3.1.82 kanamycin b acinetobacter haemolyticus 0.181 0.181 1 PMID:27785912 -2.3.1.82 kanamycin b enterococcus faecium 1.08 1.08 1 PMID:9145851 -2.3.1.82 kanamycin b escherichia coli 5.25 3.76 2 PMID:18710261 -2.3.1.82 neamine enterococcus faecium 0.42 0.419 3 PMID:12767240;PMID:14717599;PMID:9145851 -2.3.1.82 neamine enterococcus sp. 0.43 0.43 1 PMID:12566434 -2.3.1.82 neomycin enterococcus faecium 0.3 0.25 2 PMID:14717599;PMID:18295586 -2.3.1.82 neomycin pseudomonas aeruginosa 6.0 6.0 1 PMID:17417880 -2.3.1.82 neomycin serratia marcescens 11.1 9.06 3 PMID:23485681;PMID:26270859 -2.3.1.82 neomycin stenotrophomonas maltophilia 0.32 0.32 1 PMID:25092711 -2.3.1.82 neomycin b escherichia coli 3.08 3.08 1 PMID:18710261 -2.3.1.82 neomycin c acinetobacter baumannii 0.06 0.06 1 PMID:27785912 -2.3.1.82 neomycin c acinetobacter haemolyticus 0.057 0.057 1 PMID:27785912 -2.3.1.82 neomycin c enterococcus faecium 0.205 0.205 2 PMID:12767240;PMID:9145851 -2.3.1.82 netilmicin enterococcus faecium 0.512 0.512 1 PMID:9145851 -2.3.1.82 netilmicin pseudomonas aeruginosa 1.3 1.3 1 PMID:17417880 -2.3.1.82 netilmicin serratia marcescens 3.21 1.3199999999999998 4 PMID:16819836;PMID:23485681;PMID:26270859 -2.3.1.82 netilmicin stenotrophomonas maltophilia 0.3 0.3 1 PMID:25092711 -2.3.1.82 norfloxacin escherichia coli 1.08 1.08 1 PMID:18710261 -2.3.1.82 paromomycin enterococcus sp. 0.059 0.059 1 PMID:12566434 -2.3.1.82 poly-l-lys enterococcus faecium 0.0019 0.0019 1 PMID:10378269 -2.3.1.82 propionyl-coa enterococcus faecium 0.317 0.317 1 PMID:9145851 -2.3.1.82 ribostamycin acinetobacter baumannii 0.04 0.04 1 PMID:27785912 -2.3.1.82 ribostamycin acinetobacter haemolyticus 0.072 0.072 1 PMID:27785912 -2.3.1.82 ribostamycin aeromonas hydrophila 0.6 0.6 1 PMID:37920263 -2.3.1.82 ribostamycin enterococcus faecium 0.34 0.338 3 PMID:12767240;PMID:14717599;PMID:9145851 -2.3.1.82 ribostamycin serratia marcescens 5.7 4.79 2 PMID:23485681 -2.3.1.82 sisomicin acinetobacter baumannii 0.051 0.051 1 PMID:27785912 -2.3.1.82 sisomicin acinetobacter haemolyticus 0.13 0.13 1 PMID:27785912 -2.3.1.82 sisomicin aeromonas hydrophila 0.39 0.39 1 PMID:37920263 -2.3.1.82 sisomicin enterococcus faecium 0.37 0.37 1 PMID:9145851 -2.3.1.82 sisomicin serratia marcescens 5.35 2.93 3 PMID:23485681;PMID:26270859 -2.3.1.82 sisomicin stenotrophomonas maltophilia 0.16 0.16 1 PMID:25092711 -2.3.1.82 sisomicin uncultured bacterium 2.42 2.42 1 PMID:28756664 -2.3.1.82 tobramicin acinetobacter baumannii 0.022 0.022 1 PMID:27785912 -2.3.1.82 tobramicin acinetobacter haemolyticus 0.085 0.085 1 PMID:27785912 -2.3.1.82 tobramycin aeromonas hydrophila 0.15 0.15 1 PMID:37920263 -2.3.1.82 tobramycin enterococcus faecium 1.11 1.1 3 PMID:14717599;PMID:18295586;PMID:9145851 -2.3.1.82 tobramycin serratia marcescens 3.84 3.73 3 PMID:23485681;PMID:26270859 -2.3.1.82 tobramycin stenotrophomonas maltophilia 0.08 0.08 1 PMID:25092711 -2.3.1.82 tobramycin uncultured bacterium 1.2 1.2 1 PMID:28756664 -2.3.1.84 (-)-beta-citronellol cymbopogon martini 0.199 0.199 1 PMID:23415329 -2.3.1.84 2-phenylethanol fragaria x ananassa 49.6 49.6 1 PMID:22563120 -2.3.1.84 2-phenylethanol petunia x hybrida 0.91 0.91 1 PMID:17241449 -2.3.1.84 acetyl-coa fragaria x ananassa 3890.0 528.5 4 PMID:22563120 -2.3.1.84 acetyl-coa petunia x hybrida 2.32 1.3199999999999998 4 PMID:17241449 -2.3.1.84 acetyl-coa rosa hybrid cultivar 0.54 0.28 3 PMID:16525891 -2.3.1.84 benzyl alcohol fragaria x ananassa 23.5 23.5 1 PMID:22563120 -2.3.1.84 benzyl alcohol petunia x hybrida 0.82 0.82 1 PMID:17241449 -2.3.1.84 benzyl alcohol rosa hybrid cultivar 0.119 0.119 1 PMID:16525891 -2.3.1.84 butanol fragaria x ananassa 21.5 21.5 1 PMID:22563120 -2.3.1.84 cinnamyl alcohol fragaria x ananassa 1480.0 1480.0 1 PMID:22563120 -2.3.1.84 cis-hex-3-en-1-ol cymbopogon martini 0.06 0.06 1 PMID:23415329 -2.3.1.84 coniferyl alcohol petunia x hybrida 2.05 1.43 2 PMID:17241449 -2.3.1.84 ethanol fragaria x ananassa 7.5 7.5 1 PMID:22563120 -2.3.1.84 eugenol fragaria x ananassa 548.5 548.5 1 PMID:22563120 -2.3.1.84 geraniol cymbopogon martini 0.287 0.287 1 PMID:23415329 -2.3.1.84 geraniol fragaria x ananassa 70.5 70.5 1 PMID:22563120 -2.3.1.84 geraniol rosa hybrid cultivar 0.43 0.43 1 PMID:16525891 -2.3.1.84 heptanol cymbopogon martini 0.201 0.201 1 PMID:23415329 -2.3.1.84 heptanol fragaria x ananassa 170.0 170.0 1 PMID:22563120 -2.3.1.84 hexanol fragaria x ananassa 483.0 483.0 1 PMID:22563120 -2.3.1.84 methanol fragaria x ananassa 18.5 18.5 1 PMID:22563120 -2.3.1.84 nonanol cymbopogon martini 0.272 0.272 1 PMID:23415329 -2.3.1.84 octanol cymbopogon martini 0.213 0.213 1 PMID:23415329 -2.3.1.84 octanol fragaria x ananassa 466.0 466.0 1 PMID:22563120 -2.3.1.84 pentanol fragaria x ananassa 407.0 407.0 1 PMID:22563120 -2.3.1.84 phenyl ethanol rosa hybrid cultivar 0.72 0.72 1 PMID:16525891 -2.3.1.84 propanol fragaria x ananassa 17.5 17.5 1 PMID:22563120 -2.3.1.85 3-hydroxybutanoyl-coa mus musculus 6.1 6.1 1 PMID:29328619 -2.3.1.85 3-methylbutanoyl-coa mus musculus 7.2 7.2 1 PMID:29328619 -2.3.1.85 acetoacetyl-coa mus musculus 7.3 7.3 1 PMID:29328619 -2.3.1.85 acetyl-coa homo sapiens 2.7 2.7 1 PMID:16215233 -2.3.1.85 acetyl-coa mus musculus 13.7 13.35 2 PMID:29328619 -2.3.1.85 acetyl-coa rattus norvegicus 0.0317 0.0317 1 PMID:9115261 -2.3.1.85 butanoyl-coa mus musculus 10.8 10.8 1 PMID:29328619 -2.3.1.85 crotonyl-coa mus musculus 6.0 6.0 1 PMID:29328619 -2.3.1.85 malonyl-coa homo sapiens 2.7 2.7 1 PMID:16215233 -2.3.1.85 malonyl-coa mus musculus 15.6 10.3 2 PMID:29328619 -2.3.1.85 malonyl-coa rattus norvegicus 0.02 0.02 1 PMID:9115261 -2.3.1.85 methylmalonyl-coa mus musculus 4.0 4.0 1 PMID:29328619 -2.3.1.85 nadh rattus norvegicus 1.1 0.6100000000000001 2 PMID:15301544 -2.3.1.85 nadph rattus norvegicus 73.0 41.4 2 PMID:15301544 -2.3.1.85 octanoyl-coa mus musculus 4.1 4.1 1 PMID:29328619 -2.3.1.85 palmitoyl-coa mus musculus 2.5 2.5 1 PMID:29328619 -2.3.1.85 phenylacetyl-coa mus musculus 6.0 6.0 1 PMID:29328619 -2.3.1.85 succinyl-coa mus musculus 13.4 13.4 1 PMID:29328619 -2.3.1.87 2,2-difluoro-2-phenethylamine tribolium castaneum 85.0 85.0 1 PMID:32681959 -2.3.1.87 2-phenethylamine tribolium castaneum 87.0 87.0 1 PMID:32681959 -2.3.1.87 3-(trifluoromethyl)phenethylamine drosophila melanogaster 40.0 40.0 1 PMID:25406072 -2.3.1.87 3-methoxyphenethylamine drosophila melanogaster 26.0 26.0 1 PMID:25406072 -2.3.1.87 5-benzyloxytryptamine drosophila melanogaster 5.7 5.7 1 PMID:25406072 -2.3.1.87 5-hydroxytryptamine bos taurus 1.658 1.658 1 PMID:38504591 -2.3.1.87 5-hydroxytryptamine sus scrofa 3.264 3.264 1 PMID:38504591 -2.3.1.87 5-methoxytryptamine drosophila melanogaster 13.1 13.1 1 PMID:25406072 -2.3.1.87 acetyl-coa drosophila melanogaster 32.0 16.65 2 PMID:24444601;PMID:25406072 -2.3.1.87 acetyl-coa mycobacterium tuberculosis 5.6 5.6 1 PMID:29402941 -2.3.1.87 acetyl-coa mycolicibacterium smegmatis 29.0 29.0 1 PMID:29402941 -2.3.1.87 acetyl-coa saccharopolyspora erythraea 38.0 38.0 1 PMID:29402941 -2.3.1.87 acetyl-coa tribolium castaneum 52.0 52.0 1 PMID:32681959 -2.3.1.87 arachidonoyl-coa drosophila melanogaster 0.043 0.043 1 PMID:24444601 -2.3.1.87 beta-methylphenethylamine drosophila melanogaster 29.0 29.0 1 PMID:25406072 -2.3.1.87 butanoyl-coa drosophila melanogaster 0.66 0.595 2 PMID:24444601;PMID:25406072 -2.3.1.87 butanoyl-coa tribolium castaneum 14.0 14.0 1 PMID:32681959 -2.3.1.87 decanoyl-coa tribolium castaneum 3.4 3.4 1 PMID:32681959 -2.3.1.87 dopamine aedes aegypti 7.3 5.475 2 PMID:21645618 -2.3.1.87 dopamine drosophila melanogaster 21.0 21.0 1 PMID:25406072 -2.3.1.87 dopamine saccharopolyspora erythraea 2.8 2.8 1 PMID:29402941 -2.3.1.87 dopamine tribolium castaneum 26.0 26.0 1 PMID:32681959 -2.3.1.87 epinephrine aedes aegypti 6.33 3.2800000000000002 2 PMID:35178730 -2.3.1.87 hexanoyl-coa drosophila melanogaster 0.093 0.093 1 PMID:25406072 -2.3.1.87 histamine drosophila melanogaster 30.0 0.87 3 PMID:25406072 -2.3.1.87 histamine mycobacterium tuberculosis 0.5 0.5 1 PMID:29402941 -2.3.1.87 histamine mycolicibacterium smegmatis 0.48 0.48 1 PMID:29402941 -2.3.1.87 histamine tribolium castaneum 59.0 59.0 1 PMID:32681959 -2.3.1.87 methoxytryptamine aedes aegypti 7.69 5.715 2 PMID:21645618 -2.3.1.87 norepinephrine aedes aegypti 7.76 5.25 4 PMID:21645618;PMID:35178730 -2.3.1.87 norepinephrine tribolium castaneum 41.0 41.0 1 PMID:32681959 -2.3.1.87 octopamine aedes aegypti 7.26 4.91 2 PMID:21645618 -2.3.1.87 octopamine drosophila melanogaster 16.0 16.0 1 PMID:25406072 -2.3.1.87 octopamine mycobacterium tuberculosis 1.8 1.8 1 PMID:29402941 -2.3.1.87 octopamine mycolicibacterium smegmatis 3.1 3.1 1 PMID:29402941 -2.3.1.87 octopamine saccharopolyspora erythraea 4.0 4.0 1 PMID:29402941 -2.3.1.87 octopamine tribolium castaneum 40.0 40.0 1 PMID:32681959 -2.3.1.87 oleoyl-coa drosophila melanogaster 0.075 0.075 1 PMID:24444601 -2.3.1.87 palmitoyl-coa drosophila melanogaster 0.16 0.16 1 PMID:24444601 -2.3.1.87 phenethylamine drosophila melanogaster 42.0 42.0 1 PMID:25406072 -2.3.1.87 phenylethylamine saccharopolyspora erythraea 7.2 7.2 1 PMID:29402941 -2.3.1.87 propionyl-coa mycobacterium tuberculosis 0.6 0.6 1 PMID:29402941 -2.3.1.87 propionyl-coa mycolicibacterium smegmatis 2.7 2.7 1 PMID:29402941 -2.3.1.87 propionyl-coa saccharopolyspora erythraea 2.3 2.3 1 PMID:29402941 -2.3.1.87 serotonin aedes aegypti 7.545 5.5075 2 PMID:21645618 -2.3.1.87 serotonin drosophila melanogaster 17.0 17.0 1 PMID:25406072 -2.3.1.87 serotonin homo sapiens 25.9 20.3 3 PMID:18771288 -2.3.1.87 serotonin saccharopolyspora erythraea 1.5 1.5 1 PMID:29402941 -2.3.1.87 serotonin tribolium castaneum 70.0 70.0 1 PMID:32681959 -2.3.1.87 stearoyl-coa drosophila melanogaster 0.059 0.059 1 PMID:24444601 -2.3.1.87 tryptamine aedes aegypti 7.345 5.1975 2 PMID:21645618 -2.3.1.87 tryptamine drosophila melanogaster 16.0 16.0 1 PMID:25406072 -2.3.1.87 tryptamine saccharopolyspora erythraea 3.0 3.0 1 PMID:29402941 -2.3.1.87 tyramine aedes aegypti 6.775 4.9675 2 PMID:21645618 -2.3.1.87 tyramine drosophila melanogaster 238.0 238.0 1 PMID:25406072 -2.3.1.87 tyramine saccharopolyspora erythraea 18.0 18.0 1 PMID:29402941 -2.3.1.9 3-ketobutyryldithio-coa zoogloea ramigera 14.0 14.0 1 * -2.3.1.9 acetoacetyl-10-bis-demethylpantetheine 11-pivaloate zoogloea ramigera 266.0 266.0 1 PMID:2878927 -2.3.1.9 acetoacetyl-coa aspergillus fumigatus 3.0 3.0 1 PMID:32005728 -2.3.1.9 acetoacetyl-coa bacillus subtilis 80.0 80.0 1 PMID:18246303 -2.3.1.9 acetoacetyl-coa bacopa monnieri 3833.0 3833.0 1 * -2.3.1.9 acetoacetyl-coa cupriavidus necator 5000000.0 5000000.0 1 PMID:26057808 -2.3.1.9 acetoacetyl-coa escherichia coli 220.5 220.5 1 PMID:27380370 -2.3.1.9 acetoacetyl-coa metallosphaera sedula 1000.0 1000.0 1 PMID:24532060 -2.3.1.9 acetoacetyl-coa streptomyces collinus 40.1 38.150000000000006 2 PMID:11570897 -2.3.1.9 acetoacetyl-coa zoogloea ramigera 620.0 465.0 3 PMID:10545327;PMID:2878927 -2.3.1.9 acetoacetyl-s-(11-methoxymethyl)pantetheine zoogloea ramigera 353.0 353.0 1 PMID:2878927 -2.3.1.9 acetoacetyl-s-(11-t-butyldimethylsilyl)pantetheine zoogloea ramigera 434.0 434.0 1 PMID:2878927 -2.3.1.9 acetoacetyl-s-(d-pantetheine) 11-pivalate zoogloea ramigera 469.0 469.0 1 PMID:2878927 -2.3.1.9 acetoacetyl-s-(l-pantetheine) 11-pivalate zoogloea ramigera 256.0 256.0 1 PMID:2878927 -2.3.1.9 acetoacetyl-s-homopantetheine 12-pivalate zoogloea ramigera 177.0 177.0 1 PMID:2878927 -2.3.1.9 acetoacetyl-s-pantetheine zoogloea ramigera 174.0 94.0 2 PMID:2878927 -2.3.1.9 acetyl-coa aspergillus fumigatus 7.0 7.0 1 PMID:32005728 -2.3.1.9 acetyl-coa escherichia coli 6.5 6.5 1 PMID:27380370 -2.3.1.9 acetyl-coa zoogloea ramigera 2.1 2.1 1 * -2.3.1.9 coa aspergillus fumigatus 5.0 5.0 1 PMID:32005728 -2.3.1.9 coa gallus gallus 29.5 29.5 1 * -2.3.1.9 thiolytic cleavage gallus gallus 900.0 900.0 1 PMID:4698219 -2.3.1.94 propanoyl-coa saccharopolyspora erythraea 0.042 0.042 1 PMID:27441852 -2.3.1.95 4-coumaroyl-coa arachis hypogaea 0.02 0.01085 2 PMID:11432743;PMID:21441338 -2.3.1.95 4-coumaroyl-coa pinus massoniana 0.0023 0.0023 1 PMID:21441338 -2.3.1.95 4-coumaroyl-coa pinus strobus 0.0005 0.0005 1 PMID:21441338 -2.3.1.95 4-coumaroyl-coa vitis vinifera 0.003 0.003 1 PMID:21441338 -2.3.1.95 4-fluorocinnamoyl-coa arachis hypogaea 0.0113 0.0113 1 PMID:11432743 -2.3.1.95 dihydro-4-coumaroyl-coa cannabis sativa 0.00226 0.00226 1 PMID:34786774 -2.3.1.95 dihydrocaffeoyl-coa cannabis sativa 0.00917 0.00917 1 PMID:34786774 -2.3.1.95 trans-3-(3-thienyl)acryloyl-coa arachis hypogaea 0.0108 0.0108 1 PMID:11432743 -2.3.1.95 trans-3-furanacryloyl-coa arachis hypogaea 0.00533 0.00533 1 PMID:11432743 -2.3.1.97 cap5.5 peptide trypanosoma cruzi 2.11 1.13 2 PMID:24444291 -2.3.1.97 gcggskvk trypanosoma brucei 18.2 18.2 1 PMID:16480339 -2.3.1.97 gqlftsln leishmania major 24.0 24.0 1 PMID:16480339 -2.3.1.97 hiv1 gag protein n-terminal peptide homo sapiens 0.265 0.186 4 PMID:18089753 -2.3.1.97 hiv1 nef protein n-terminal peptide homo sapiens 0.052 0.041999999999999996 4 PMID:18089753 -2.3.1.97 myristoyl-coa arabidopsis thaliana 0.234 0.234 1 PMID:14705787 -2.3.1.97 myristoyl-coa homo sapiens 0.41 0.41 1 PMID:32111831 -2.3.1.97 myristoyl-coa leishmania major 23.6 23.6 1 PMID:16480339 -2.3.1.97 myristoyl-coa saccharomyces cerevisiae 13.8 7.1450000000000005 2 PMID:11123906;PMID:14705787 -2.3.1.97 myristoyl-coa trypanosoma brucei 76.8 76.8 1 PMID:16480339 -2.3.1.97 myristoyl-coa trypanosoma cruzi 0.34 0.34 1 PMID:24444291 -2.3.1.99 3-o-(4-coumaroyl)quinate bambusa multiplex 3.9 3.9 1 PMID:36305861 -2.3.1.99 3-o-feruloylquinate bambusa multiplex 3.9 3.9 1 PMID:36305861 -2.3.1.99 4-coumaroyl-coa bambusa multiplex 14.0 14.0 1 PMID:36305861 -2.3.1.99 4-coumaroyl-coa lonicera japonica 1.88 1.88 1 * -2.3.1.99 5-o-caffeoylquinate lonicera japonica 0.9 0.9 1 * -2.3.1.99 caffeoyl-coa lonicera japonica 1.3 1.3 1 * -2.3.1.99 coa bambusa multiplex 3.9 3.9 1 PMID:36305861 -2.3.1.99 feruloyl-coa bambusa multiplex 10.0 10.0 1 PMID:36305861 -2.3.1.99 quinate bambusa multiplex 15.0 15.0 1 PMID:36305861 -2.3.1.99 quinate lonicera japonica 2.75 2.2 2 * -2.3.1.99 shikimate lonicera japonica 0.15 0.15 1 * -2.3.2.10 l-alanyl-trna weissella viridescens 26.7 26.7 1 PMID:15901708 -2.3.2.10 l-alanyl-trnaala weissella viridescens 11.0 11.0 1 PMID:12679335 -2.3.2.12 acphe-trna escherichia coli 0.0333 0.0233 2 PMID:3545299 -2.3.2.12 acphe-trna oryctolagus cuniculus 0.333 0.0483 3 PMID:9126380;PMID:9308906 -2.3.2.12 acphe-trna saccharomyces cerevisiae 0.0508 0.03 5 PMID:11434779;PMID:12433929 -2.3.2.12 cytidine-puromycin escherichia coli 19.0 19.0 1 PMID:16799464 -2.3.2.12 formylmethionyl-trna escherichia coli 0.138 0.138 1 PMID:3545299 -2.3.2.12 puromycin escherichia coli 0.17 0.17 1 PMID:16799464 -2.3.2.13 alpha-carbobenzoxy-lysine streptomyces mobaraensis 0.00035 0.00035 1 PMID:9193708 -2.3.2.13 beta-casein homo sapiens 16.1 16.1 1 PMID:16820332 -2.3.2.13 butylamine streptomyces mobaraensis 0.00055 0.00055 1 PMID:9193708 -2.3.2.13 cbz-gln-ala pagrus major 51.0 51.0 1 PMID:15010546 -2.3.2.13 cbz-gln-gly homo sapiens 0.088 0.088 1 PMID:25333388 -2.3.2.13 cbz-gln-gly pagrus major 96.0 96.0 1 PMID:15010546 -2.3.2.13 cbz-gln-gly-gly pagrus major 102.0 102.0 1 PMID:15010546 -2.3.2.13 cbz-gln-gly-oh streptomyces mobaraensis 27.37 27.37 1 PMID:31350615 -2.3.2.13 cbz-gln-leu pagrus major 127.0 127.0 1 PMID:15010546 -2.3.2.13 cbz-gln-phe pagrus major 54.0 54.0 1 PMID:15010546 -2.3.2.13 cbz-gln-ser pagrus major 66.0 66.0 1 PMID:15010546 -2.3.2.13 cbz-gln-val pagrus major 71.0 71.0 1 PMID:15010546 -2.3.2.13 ethylamine streptomyces mobaraensis 0.00055 0.00055 1 PMID:9193708 -2.3.2.13 hydroxylamine streptomyces mobaraensis 1.83 1.83 1 * -2.3.2.13 involucrin homo sapiens 0.00233 0.00233 1 PMID:11443109 -2.3.2.13 lgpqskvig homo sapiens 78.0 78.0 1 PMID:16820332 -2.3.2.13 lgpqslvig homo sapiens 44.0 44.0 1 PMID:16820332 -2.3.2.13 loricrin homo sapiens 0.0035 0.0035 1 PMID:11443109 -2.3.2.13 methylamine cavia porcellus 0.467 0.467 1 PMID:2873138 -2.3.2.13 methylamine homo sapiens 1.86 1.86 1 PMID:2873138 -2.3.2.13 methylamine rattus norvegicus 0.32 0.32 1 PMID:2873138 -2.3.2.13 n,n'-dimethyl casein glutamine homo sapiens 1.5 1.5 1 PMID:27551108 -2.3.2.13 n,n'-dimethylcasein rattus norvegicus 0.532 0.532 1 PMID:1970312 -2.3.2.13 n-cbz-gln-gly streptomyces hygroscopicus 31.5 31.5 1 PMID:26272462 -2.3.2.13 n-cbz-glu-gly streptomyces mobaraensis 1.83 1.83 1 * -2.3.2.13 nalpha-benzyloxycarbonyl-l-gln-gly homo sapiens 0.19 0.19 1 PMID:20547769 -2.3.2.13 nalpha-benzyloxycarbonyl-l-glutaminylglycine streptomyces mobaraensis 35.48 35.48 1 PMID:21193394 -2.3.2.13 nqenvspltllklgn homo sapiens 147.0 147.0 1 PMID:16820332 -2.3.2.13 nqenvspltllrlgn homo sapiens 77.3 40.05 2 PMID:16820332 -2.3.2.13 nqeqvspltllklgn homo sapiens 175.0 175.0 1 PMID:16820332 -2.3.2.13 pentylamine cavia porcellus 0.064 0.064 1 PMID:29960064 -2.3.2.13 pentylamine pacifastacus leniusculus 0.0096 0.00805 2 PMID:29960064 -2.3.2.13 propylamine streptomyces mobaraensis 0.0004 0.0004 1 PMID:9193708 -2.3.2.13 small proline-rich protein 3 homo sapiens 0.00433 0.00433 1 PMID:11443109 -2.3.2.13 z-gln-gly streptomyces mobaraensis 0.85 0.85 1 PMID:28245818 -2.3.2.13 z-glu(hc)-gly-oh cavia porcellus 0.33 0.33 1 PMID:27124709 -2.3.2.13 z-glu(hmc)-gly-oh cavia porcellus 0.32 0.32 1 PMID:27124709 -2.3.2.13 z-phe-gamma-abu-7-hydroxy-4-methylcoumarin cavia porcellus 0.52 0.52 1 PMID:27124709 -2.3.2.13 z-phe-gamma-abu-7-hydroxycoumarin cavia porcellus 0.3 0.3 1 PMID:27124709 -2.3.2.2 (gamma-l-glutamyl)-4-nitroanilide bacillus subtilis 0.32 0.32 1 PMID:33636215 -2.3.2.2 4-nitroanilide homo sapiens 1150.0 1150.0 1 PMID:19463 -2.3.2.2 4-nitroanilide rattus norvegicus 1250.0 1250.0 1 PMID:19463 -2.3.2.2 5-l-glutamyl-4-nitroanilide bacillus licheniformis 109.5 97.0 3 PMID:16850301;PMID:19340483;PMID:20673217 -2.3.2.2 5-l-glutamyl-4-nitroanilide bacillus subtilis 43.33 43.33 1 PMID:12892879 -2.3.2.2 5-l-glutamyl-4-nitroanilide escherichia coli 0.62 0.62 1 PMID:19788059 -2.3.2.2 5-l-glutamyl-4-nitroanilide raphanus sativus 39.0 27.0 4 PMID:16495652 -2.3.2.2 gamma-glu-cys raphanus sativus 31.0 21.5 4 PMID:16495652 -2.3.2.2 gs-bimane raphanus sativus 40.0 27.0 4 PMID:16495652 -2.3.2.2 gsh raphanus sativus 32.0 21.5 4 PMID:16495652 -2.3.2.2 gssg raphanus sativus 32.0 28.5 4 PMID:16495652 -2.3.2.2 l-gamma-glutamyl-4-nitroanilide bacillus licheniformis 106.7 61.370000000000005 2 PMID:27246377;PMID:28365292 -2.3.2.23 [ube2w]-s-ubiquitinyl-l-cysteine homo sapiens 0.375 0.1955 2 PMID:32401531 -2.3.2.23 [ubiquitin carrier protein ubc4]-l-cysteine homo sapiens 0.072 0.072 1 PMID:11195973 -2.3.2.23 [ubiquitin-carrier-protein ubc2b]-l-cysteine homo sapiens 3.4 3.4 1 PMID:16595681 -2.3.2.24 [cytochrome c]-l-lysine oryctolagus cuniculus 0.00617 0.00617 1 PMID:2550069 -2.3.2.24 [histone h2a]-l-lysine oryctolagus cuniculus 0.0013 0.00115 2 PMID:2843516 -2.3.2.24 [histone h2b]-l-lysine oryctolagus cuniculus 0.0033 0.00275 2 PMID:2843516 -2.3.2.24 [histone h3]-l-lysine oryctolagus cuniculus 0.003 0.003 1 PMID:2550069 -2.3.2.26 [ubc5b]-l-lysine homo sapiens 0.012 0.012 1 PMID:30287686 -2.3.2.27 [ube2w]-s-ubiquitinyl-l-cysteine homo sapiens 0.375 0.375 1 PMID:32401531 -2.3.2.5 2-amino-5-(butan-2-ylamino)-5-oxopentanoic acid oryctolagus cuniculus 0.07 0.07 1 PMID:22120669 -2.3.2.5 2-amino-5-(cyclohexylamino)-5-oxopentanoic acid oryctolagus cuniculus 0.061 0.061 1 PMID:22120669 -2.3.2.5 2-amino-5-(cyclopropylamino)-5-oxopentanoic acid oryctolagus cuniculus 0.045 0.045 1 PMID:22120669 -2.3.2.5 2-amino-5-[(2-methylbutyl)amino]-5-oxopentanoic acid oryctolagus cuniculus 0.19 0.19 1 PMID:22120669 -2.3.2.5 2-amino-5-[(2s)-butan-2-ylamino]-5-oxopentanoic acid oryctolagus cuniculus 0.11 0.11 1 PMID:22120669 -2.3.2.5 2-amino-5-[[(2s)-2-methylbutyl]amino]-5-oxopentanoic acid oryctolagus cuniculus 0.21 0.21 1 PMID:22120669 -2.3.2.5 2-amino-5-oxo-5-(propan-2-ylamino)pentanoic acid oryctolagus cuniculus 0.068 0.068 1 PMID:22120669 -2.3.2.5 2-amino-5-oxo-5-[(2-phenylethyl)amino]pentanoic acid oryctolagus cuniculus 0.17 0.17 1 PMID:22120669 -2.3.2.5 [gln1]-fertilization promoting peptide carica papaya 37.7 37.7 1 PMID:14719800 -2.3.2.5 [gln1]-fertilization promoting peptide homo sapiens 69.6 69.6 1 PMID:14719800 -2.3.2.5 [gln1]-gastrin carica papaya 31.6 31.6 1 PMID:14719800 -2.3.2.5 [gln1]-gastrin homo sapiens 54.1 54.1 1 PMID:14719800 -2.3.2.5 [gln1]-gonadotropin releasing-hormone carica papaya 72.4 72.4 1 PMID:14719800 -2.3.2.5 [gln1]-gonadotropin releasing-hormone homo sapiens 69.2 69.2 1 PMID:14719800 -2.3.2.5 [gln1]-neurotensin carica papaya 37.7 37.7 1 PMID:14719800 -2.3.2.5 [gln1]-neurotensin homo sapiens 48.8 48.8 1 PMID:14719800 -2.3.2.5 [gln1]-thyrotropin releasing-hormone homo sapiens 82.8 82.8 1 PMID:14719800 -2.3.2.5 efrh-nh2 homo sapiens 0.00022 0.00022 1 PMID:19921850 -2.3.2.5 efrhhdsgye-nh2 homo sapiens 0.00042 0.00042 1 PMID:19921850 -2.3.2.5 gln 7-amido-4-methylcoumarin carica papaya 39.4 39.4 1 PMID:14719800 -2.3.2.5 gln(3)-amyloid-beta peptide 3-11 amide homo sapiens 55.0 48.2 2 PMID:15063747 -2.3.2.5 gln(3)-amyloid-beta peptide 3-21 amide homo sapiens 62.0 62.0 1 PMID:15063747 -2.3.2.5 gln(3)-amyloid-beta peptide 3-40 amide homo sapiens 40.0 40.0 1 PMID:15063747 -2.3.2.5 gln-2-naphthylamide homo sapiens 5.4 5.4 1 PMID:18072935 -2.3.2.5 gln-7-amido-4-methylcoumarin homo sapiens 5.3 5.3 1 PMID:14719800 -2.3.2.5 gln-7-amido-4-methylcoumarin porphyromonas gingivalis 4.71 4.71 1 PMID:33837744 -2.3.2.5 gln-7-amido-4-methylcoumarin prevotella intermedia 8.51 8.51 1 PMID:33837744 -2.3.2.5 gln-7-amido-4-methylcoumarin tannerella forsythia 4.49 4.49 1 PMID:33837744 -2.3.2.5 gln-ala carica papaya 69.8 68.94999999999999 2 PMID:14719800 -2.3.2.5 gln-ala homo sapiens 57.2 47.6 3 PMID:14719800;PMID:7999256 -2.3.2.5 gln-ala-ala-ala-ala-nh2 carica papaya 74.6 74.6 1 PMID:14719800 -2.3.2.5 gln-ala-ala-ala-ala-nh2 homo sapiens 60.5 60.5 1 PMID:14719800 -2.3.2.5 gln-ala-ala-nh2 carica papaya 83.2 83.2 1 PMID:14719800 -2.3.2.5 gln-ala-ala-nh2 homo sapiens 76.3 76.3 1 PMID:14719800 -2.3.2.5 gln-ala-ala-ser-ala-ala-nh2 carica papaya 78.5 78.5 1 PMID:14719800 -2.3.2.5 gln-ala-ala-ser-ala-ala-nh2 homo sapiens 55.3 55.3 1 PMID:14719800 -2.3.2.5 gln-arg-gly-ile-nh2 carica papaya 49.2 48.8 2 PMID:14719800 -2.3.2.5 gln-arg-gly-ile-nh2 homo sapiens 33.5 31.65 2 PMID:14719800 -2.3.2.5 gln-arg-tyr-phe-nh2 carica papaya 48.9 48.9 1 PMID:14719800 -2.3.2.5 gln-arg-tyr-phe-nh2 homo sapiens 29.6 29.6 1 PMID:14719800 -2.3.2.5 gln-asn-gly-ile-nh2 carica papaya 51.4 51.4 1 PMID:14719800 -2.3.2.5 gln-asn-gly-ile-nh2 homo sapiens 56.6 56.6 1 PMID:14719800 -2.3.2.5 gln-beta-naphthylamide homo sapiens 20.6 20.6 1 PMID:14719800 -2.3.2.5 gln-beta-naphthylamine carica papaya 51.4 51.4 1 PMID:14719800 -2.3.2.5 gln-gln carica papaya 43.2 43.2 1 PMID:14719800 -2.3.2.5 gln-gln homo sapiens 20.7 8.615 10 PMID:14680951;PMID:14719800;PMID:16084398;PMID:16135565;PMID:19804409;PMID:7999256 -2.3.2.5 gln-gln mus musculus 8.66 8.66 1 PMID:19804409 -2.3.2.5 gln-gln-gln homo sapiens 0.755 0.755 1 PMID:7999256 -2.3.2.5 gln-gln-oh homo sapiens 12.8 12.8 1 PMID:12196024 -2.3.2.5 gln-gln-tyr-phe-nh2 carica papaya 52.9 52.9 1 PMID:14719800 -2.3.2.5 gln-gln-tyr-phe-nh2 homo sapiens 41.4 41.4 1 PMID:14719800 -2.3.2.5 gln-glu carica papaya 50.3 47.349999999999994 2 PMID:14719800 -2.3.2.5 gln-glu homo sapiens 24.7 18.9 3 PMID:14719800;PMID:19804409 -2.3.2.5 gln-glu mus musculus 7.79 7.79 1 PMID:19804409 -2.3.2.5 gln-glu-ala-ala-nh2 carica papaya 53.7 53.7 1 PMID:14719800 -2.3.2.5 gln-glu-ala-ala-nh2 homo sapiens 46.0 46.0 1 PMID:14719800 -2.3.2.5 gln-glu-ala-phe-nh2 carica papaya 48.5 48.5 1 PMID:14719800 -2.3.2.5 gln-glu-ala-phe-nh2 homo sapiens 39.0 39.0 1 PMID:14719800 -2.3.2.5 gln-glu-asp-leu-nh2 carica papaya 58.5 56.05 2 PMID:14719800 -2.3.2.5 gln-glu-asp-leu-nh2 homo sapiens 45.8 45.7 2 PMID:14719800 -2.3.2.5 gln-glu-tyr-ala-nh2 carica papaya 44.7 44.7 1 PMID:14719800 -2.3.2.5 gln-glu-tyr-ala-nh2 homo sapiens 42.1 42.1 1 PMID:14719800 -2.3.2.5 gln-glu-tyr-nh2 carica papaya 53.6 53.6 1 PMID:14719800 -2.3.2.5 gln-glu-tyr-nh2 homo sapiens 45.1 45.1 1 PMID:14719800 -2.3.2.5 gln-glu-tyr-phe-nh2 carica papaya 54.6 54.6 1 PMID:14719800 -2.3.2.5 gln-glu-tyr-phe-nh2 homo sapiens 46.0 46.0 1 PMID:14719800 -2.3.2.5 gln-gly carica papaya 45.8 45.8 1 PMID:14719800 -2.3.2.5 gln-gly homo sapiens 13.2 1.65 3 PMID:14719800;PMID:19804409;PMID:7999256 -2.3.2.5 gln-gly mus musculus 4.57 4.57 1 PMID:19804409 -2.3.2.5 gln-gly-pro carica papaya 41.7 41.7 1 PMID:14719800 -2.3.2.5 gln-gly-pro homo sapiens 25.3 14.65 2 PMID:14719800;PMID:19804409 -2.3.2.5 gln-gly-pro mus musculus 11.4 11.4 1 PMID:19804409 -2.3.2.5 gln-his-pro-nh2 homo sapiens 83.0 83.0 1 PMID:12196024 -2.3.2.5 gln-his-tyr-phe-nh2 carica papaya 75.9 75.9 1 PMID:14719800 -2.3.2.5 gln-his-tyr-phe-nh2 homo sapiens 55.4 55.4 1 PMID:14719800 -2.3.2.5 gln-lys-arg-leu-nh2 carica papaya 58.1 53.150000000000006 2 PMID:14719800 -2.3.2.5 gln-lys-arg-leu-nh2 homo sapiens 33.4 32.5 2 PMID:14719800 -2.3.2.5 gln-nh2 carica papaya 45.2 45.0 2 PMID:14719800 -2.3.2.5 gln-nh2 homo sapiens 20.7 12.8 5 PMID:12196024;PMID:14680951;PMID:14719800;PMID:7999256 -2.3.2.5 gln-phe-ala homo sapiens 7.5 7.5 1 PMID:19804409 -2.3.2.5 gln-phe-ala mus musculus 24.1 24.1 1 PMID:19804409 -2.3.2.5 gln-phe-ala-nh2 carica papaya 132.0 132.0 1 PMID:14719800 -2.3.2.5 gln-phe-ala-nh2 homo sapiens 109.0 109.0 1 PMID:14719800 -2.3.2.5 gln-pro-tyr-phe-nh2 carica papaya 18.8 18.8 1 PMID:14719800 -2.3.2.5 gln-pro-tyr-phe-nh2 homo sapiens 31.7 31.7 1 PMID:14719800 -2.3.2.5 gln-ser-tyr-phe-nh2 carica papaya 64.9 64.9 1 PMID:14719800 -2.3.2.5 gln-ser-tyr-phe-nh2 homo sapiens 52.8 52.8 1 PMID:14719800 -2.3.2.5 gln-tert-butyl ester carica papaya 49.4 49.4 1 PMID:14719800 -2.3.2.5 gln-tert-butyl ester homo sapiens 20.9 16.0 3 PMID:14680951;PMID:14719800;PMID:16084398 -2.3.2.5 gln-trp-ala-nh2 carica papaya 151.8 142.4 2 PMID:14719800 -2.3.2.5 gln-trp-ala-nh2 homo sapiens 50.0 48.5 2 PMID:14719800 -2.3.2.5 gln-tyr homo sapiens 94.0 94.0 1 PMID:14719800 -2.3.2.5 gln-tyr-ala carica papaya 104.0 104.0 1 PMID:14719800 -2.3.2.5 gln-tyr-ala homo sapiens 125.0 66.35 2 PMID:14719800;PMID:19804409 -2.3.2.5 gln-tyr-ala mus musculus 22.9 22.9 1 PMID:19804409 -2.3.2.5 gln-tyr-ala-oh homo sapiens 220.0 172.5 2 PMID:12196024 -2.3.2.5 gln-val homo sapiens 17.2 17.2 1 PMID:14719800 -2.3.2.5 glucagon(3-29) homo sapiens 10.0 10.0 1 PMID:15063747 -2.3.2.5 h-gln-7-amido-4-methylcoumarin arabidopsis thaliana 19.0 19.0 1 PMID:17261077 -2.3.2.5 h-gln-7-amido-4-methylcoumarin homo sapiens 1.07 1.07 1 PMID:18486145 -2.3.2.5 h-gln-7-amido-4-methylcoumarin solanum tuberosum 25.0 25.0 1 PMID:17261077 -2.3.2.5 h-gln-ala-oh arabidopsis thaliana 30.0 30.0 1 PMID:17261077 -2.3.2.5 h-gln-ala-oh drosophila melanogaster 17.0 16.5 2 PMID:17722885 -2.3.2.5 h-gln-ala-oh solanum tuberosum 37.7 37.7 1 PMID:17261077 -2.3.2.5 h-gln-asp-glu-leu-nh2 arabidopsis thaliana 13.1 13.1 1 PMID:17261077 -2.3.2.5 h-gln-asp-glu-leu-nh2 drosophila melanogaster 14.0 14.0 1 PMID:17722885 -2.3.2.5 h-gln-asp-glu-leu-nh2 solanum tuberosum 40.0 40.0 1 PMID:17261077 -2.3.2.5 h-gln-beta-naphthylamide arabidopsis thaliana 8.0 8.0 1 PMID:17261077 -2.3.2.5 h-gln-beta-naphthylamide drosophila melanogaster 1.3 1.2000000000000002 2 PMID:17722885 -2.3.2.5 h-gln-beta-naphthylamide homo sapiens 3.4 3.4 1 PMID:18486145 -2.3.2.5 h-gln-beta-naphthylamide solanum tuberosum 45.0 45.0 1 PMID:17261077 -2.3.2.5 h-gln-gln-oh arabidopsis thaliana 17.0 17.0 1 PMID:17261077 -2.3.2.5 h-gln-gln-oh drosophila melanogaster 7.4 7.2 2 PMID:17722885 -2.3.2.5 h-gln-gln-oh homo sapiens 2.72 2.72 1 PMID:18486145 -2.3.2.5 h-gln-gln-oh solanum tuberosum 24.0 24.0 1 PMID:17261077 -2.3.2.5 h-gln-glu-ala-phe-nh2 arabidopsis thaliana 14.9 14.9 1 PMID:17261077 -2.3.2.5 h-gln-glu-ala-phe-nh2 drosophila melanogaster 12.7 11.85 2 PMID:17722885 -2.3.2.5 h-gln-glu-ala-phe-nh2 solanum tuberosum 64.0 64.0 1 PMID:17261077 -2.3.2.5 h-gln-glu-oh arabidopsis thaliana 16.4 16.4 1 PMID:17261077 -2.3.2.5 h-gln-glu-oh drosophila melanogaster 38.0 38.0 1 PMID:17722885 -2.3.2.5 h-gln-glu-oh homo sapiens 2.65 2.65 1 PMID:18486145 -2.3.2.5 h-gln-glu-oh solanum tuberosum 30.0 30.0 1 PMID:17261077 -2.3.2.5 h-gln-glu-tyr-ala-nh2 solanum tuberosum 49.0 49.0 1 PMID:17261077 -2.3.2.5 h-gln-glu-tyr-phe-nh2 arabidopsis thaliana 9.2 9.2 1 PMID:17261077 -2.3.2.5 h-gln-glu-tyr-phe-nh2 drosophila melanogaster 6.9 6.9 1 PMID:17722885 -2.3.2.5 h-gln-glu-tyr-phe-nh2 solanum tuberosum 50.0 50.0 1 PMID:17261077 -2.3.2.5 h-gln-gly-oh arabidopsis thaliana 22.0 22.0 1 PMID:17261077 -2.3.2.5 h-gln-gly-oh drosophila melanogaster 9.0 6.95 2 PMID:17722885 -2.3.2.5 h-gln-gly-oh homo sapiens 1.66 1.66 1 PMID:18486145 -2.3.2.5 h-gln-gly-oh solanum tuberosum 8.0 8.0 1 PMID:17261077 -2.3.2.5 h-gln-gly-pro-oh arabidopsis thaliana 15.7 15.7 1 PMID:17261077 -2.3.2.5 h-gln-gly-pro-oh drosophila melanogaster 16.0 15.0 2 PMID:17722885 -2.3.2.5 h-gln-gly-pro-oh homo sapiens 4.02 4.02 1 PMID:18486145 -2.3.2.5 h-gln-gly-pro-oh solanum tuberosum 32.0 32.0 1 PMID:17261077 -2.3.2.5 h-gln-lys-arg-leu-nh2 arabidopsis thaliana 20.6 20.6 1 PMID:17261077 -2.3.2.5 h-gln-lys-arg-leu-nh2 drosophila melanogaster 7.0 7.0 1 PMID:17722885 -2.3.2.5 h-gln-lys-arg-leu-nh2 solanum tuberosum 62.0 62.0 1 PMID:17261077 -2.3.2.5 h-gln-nh2 arabidopsis thaliana 25.0 25.0 1 PMID:17261077 -2.3.2.5 h-gln-nh2 solanum tuberosum 37.0 37.0 1 PMID:17261077 -2.3.2.5 h-gln-phe-ala-nh2 arabidopsis thaliana 55.0 55.0 1 PMID:17261077 -2.3.2.5 h-gln-phe-ala-nh2 solanum tuberosum 57.0 57.0 1 PMID:17261077 -2.3.2.5 h-gln-phe-ala-oh drosophila melanogaster 22.0 19.0 2 PMID:17722885 -2.3.2.5 h-gln-ser-tyr-phe-nh2 solanum tuberosum 44.0 44.0 1 PMID:17261077 -2.3.2.5 h-gln-tyr-ala-oh drosophila melanogaster 17.04 17.04 1 PMID:17722885 -2.3.2.5 h-gln-val-ala-oh arabidopsis thaliana 10.9 10.9 1 PMID:17261077 -2.3.2.5 h-gln-val-ala-oh drosophila melanogaster 5.3 4.16 2 PMID:17722885 -2.3.2.5 h-gln-val-ala-oh solanum tuberosum 27.0 27.0 1 PMID:17261077 -2.3.2.5 l-gamma-glutamyl-(+)-3-aminobutyric acid oryctolagus cuniculus 0.054 0.054 1 PMID:22120669 -2.3.2.5 l-gamma-glutamyl-(+)-3-aminoisobutyric acid oryctolagus cuniculus 0.21 0.21 1 PMID:22120669 -2.3.2.5 l-gamma-glutamyl-beta-alanine oryctolagus cuniculus 0.18 0.18 1 PMID:22120669 -2.3.2.5 l-gamma-glutamyl-ethylamine oryctolagus cuniculus 0.038 0.038 1 PMID:22120669 -2.3.2.5 l-gamma-glutamyl-methylamine oryctolagus cuniculus 0.02 0.02 1 PMID:22120669 -2.3.2.5 l-gamma-glutamyl-n-butylamine oryctolagus cuniculus 0.21 0.21 1 PMID:22120669 -2.3.2.5 l-gamma-glutamyl-n-propylamine oryctolagus cuniculus 0.23 0.23 1 PMID:22120669 -2.3.2.5 l-gamma-glutamyl-tert-butylamine oryctolagus cuniculus 0.012 0.012 1 PMID:22120669 -2.3.2.5 l-gamma-glutamylaniline oryctolagus cuniculus 0.036 0.036 1 PMID:22120669 -2.3.2.5 l-gamma-glutamylbenzylamine oryctolagus cuniculus 0.4 0.4 1 PMID:22120669 -2.3.2.5 l-gamma-glutamylcyclopentylamine oryctolagus cuniculus 0.076 0.076 1 PMID:22120669 -2.3.2.5 l-gamma-glutamylglycine oryctolagus cuniculus 0.14 0.14 1 PMID:22120669 -2.3.2.5 l-gamma-glutamylneohexylamine oryctolagus cuniculus 0.18 0.18 1 PMID:22120669 -2.3.2.5 l-gamma-glutamylneopentylamine oryctolagus cuniculus 0.035 0.035 1 PMID:22120669 -2.3.2.5 l-gln-2-naphthylamide arabidopsis thaliana 8.0 8.0 1 PMID:17261077 -2.3.2.5 l-gln-2-naphthylamide mus musculus 22.0 22.0 1 PMID:16201766 -2.3.2.5 l-gln-2-naphthylamide myxococcus xanthus 18.9 18.9 1 PMID:20868223 -2.3.2.5 l-gln-2-naphthylamide solanum tuberosum 45.0 45.0 1 PMID:17261077 -2.3.2.5 l-gln-2-naphthylamide xanthomonas campestris 1.4 1.4 1 PMID:20558177 -2.3.2.5 l-gln-2-naphthylamide zymomonas mobilis 2.7 2.7 1 PMID:20868223 -2.3.2.5 l-gln-7-amido-4-methylcoumarin arabidopsis thaliana 19.0 19.0 1 PMID:17261077 -2.3.2.5 l-gln-7-amido-4-methylcoumarin mus musculus 6.0 6.0 1 PMID:16201766 -2.3.2.5 l-gln-7-amido-4-methylcoumarin myxococcus xanthus 7.1 7.1 1 PMID:20868223 -2.3.2.5 l-gln-7-amido-4-methylcoumarin solanum tuberosum 25.0 25.0 1 PMID:17261077 -2.3.2.5 l-gln-7-amido-4-methylcoumarin zymomonas mobilis 0.45 0.45 1 PMID:20868223 -2.3.2.5 l-gln-amide myxococcus xanthus 35.7 35.7 1 PMID:20868223 -2.3.2.5 l-gln-amide zymomonas mobilis 61.5 61.5 1 PMID:20868223 -2.3.2.5 l-gln-gly arabidopsis thaliana 22.0 22.0 1 PMID:17261077 -2.3.2.5 l-gln-gly mus musculus 12.4 12.4 1 PMID:16201766 -2.3.2.5 l-gln-gly solanum tuberosum 8.0 8.0 1 PMID:17261077 -2.3.2.5 l-gln-gly zymomonas mobilis 32.0 32.0 1 PMID:20868223 -2.3.2.5 l-gln-gly-l-pro arabidopsis thaliana 15.7 15.7 1 PMID:17261077 -2.3.2.5 l-gln-gly-l-pro mus musculus 21.6 21.6 1 PMID:16201766 -2.3.2.5 l-gln-gly-l-pro solanum tuberosum 32.0 32.0 1 PMID:17261077 -2.3.2.5 l-gln-l-ala arabidopsis thaliana 30.0 30.0 1 PMID:17261077 -2.3.2.5 l-gln-l-ala mus musculus 42.0 42.0 1 PMID:16201766 -2.3.2.5 l-gln-l-ala solanum tuberosum 37.7 37.7 1 PMID:17261077 -2.3.2.5 l-gln-l-arg-gly-l-ile-nh2 mus musculus 34.0 34.0 1 PMID:16201766 -2.3.2.5 l-gln-l-asn-gly-l-ile-nh2 mus musculus 68.0 68.0 1 PMID:16201766 -2.3.2.5 l-gln-l-asp-l-glu-l-leu-nh2 arabidopsis thaliana 13.1 13.1 1 PMID:17261077 -2.3.2.5 l-gln-l-asp-l-glu-l-leu-nh2 solanum tuberosum 40.0 40.0 1 PMID:17261077 -2.3.2.5 l-gln-l-gln arabidopsis thaliana 17.0 17.0 1 PMID:17261077 -2.3.2.5 l-gln-l-gln mus musculus 32.0 32.0 1 PMID:16201766 -2.3.2.5 l-gln-l-gln myxococcus xanthus 31.7 31.7 1 PMID:20868223 -2.3.2.5 l-gln-l-gln solanum tuberosum 24.0 24.0 1 PMID:17261077 -2.3.2.5 l-gln-l-gln zymomonas mobilis 0.27 0.27 1 PMID:20868223 -2.3.2.5 l-gln-l-glu arabidopsis thaliana 16.4 16.4 1 PMID:17261077 -2.3.2.5 l-gln-l-glu mus musculus 29.0 29.0 1 PMID:16201766 -2.3.2.5 l-gln-l-glu myxococcus xanthus 12.8 12.8 1 PMID:20868223 -2.3.2.5 l-gln-l-glu solanum tuberosum 30.0 30.0 1 PMID:17261077 -2.3.2.5 l-gln-l-glu zymomonas mobilis 0.021 0.021 1 PMID:20868223 -2.3.2.5 l-gln-l-glu-l-ala-l-phe-nh2 arabidopsis thaliana 14.9 14.9 1 PMID:17261077 -2.3.2.5 l-gln-l-glu-l-ala-l-phe-nh2 solanum tuberosum 64.0 64.0 1 PMID:17261077 -2.3.2.5 l-gln-l-glu-l-tyr-l-ala-nh2 solanum tuberosum 49.0 49.0 1 PMID:17261077 -2.3.2.5 l-gln-l-glu-l-tyr-l-phe-nh2 arabidopsis thaliana 9.2 9.2 1 PMID:17261077 -2.3.2.5 l-gln-l-glu-l-tyr-l-phe-nh2 solanum tuberosum 50.0 50.0 1 PMID:17261077 -2.3.2.5 l-gln-l-lys-l-arg-l-leu-nh2 arabidopsis thaliana 20.6 20.6 1 PMID:17261077 -2.3.2.5 l-gln-l-lys-l-arg-l-leu-nh2 solanum tuberosum 62.0 62.0 1 PMID:17261077 -2.3.2.5 l-gln-l-phe-l-ala-nh2 arabidopsis thaliana 55.0 55.0 1 PMID:17261077 -2.3.2.5 l-gln-l-phe-l-ala-nh2 solanum tuberosum 57.0 57.0 1 PMID:17261077 -2.3.2.5 l-gln-l-ser-l-tyr-l-phe-nh2 solanum tuberosum 44.0 44.0 1 PMID:17261077 -2.3.2.5 l-gln-l-thr-gly-l-ile-nh2 mus musculus 23.0 23.0 1 PMID:16201766 -2.3.2.5 l-gln-l-trp-l-ala-nh2 mus musculus 41.0 41.0 1 PMID:16201766 -2.3.2.5 l-gln-l-val-l-ala-nh2 arabidopsis thaliana 10.9 10.9 1 PMID:17261077 -2.3.2.5 l-gln-l-val-l-ala-nh2 solanum tuberosum 27.0 27.0 1 PMID:17261077 -2.3.2.5 l-gln-nh2 arabidopsis thaliana 25.0 25.0 1 PMID:17261077 -2.3.2.5 l-gln-nh2 solanum tuberosum 37.0 37.0 1 PMID:17261077 -2.3.2.5 l-gln-tert-butyl ester arabidopsis thaliana 21.0 21.0 1 PMID:17261077 -2.3.2.5 l-gln-tert-butyl ester myxococcus xanthus 64.9 64.9 1 PMID:20868223 -2.3.2.5 l-gln-tert-butyl ester solanum tuberosum 31.3 31.3 1 PMID:17261077 -2.3.2.5 l-gln-tert-butyl ester zymomonas mobilis 128.0 128.0 1 PMID:20868223 -2.3.2.5 l-glutamine tert-butyl ester carica papaya 33.0 33.0 1 * -2.3.2.5 l-glutaminyl 2-naphthylamide ixodes scapularis 8.8 8.8 1 PMID:24598748 -2.3.2.5 l-glutaminyl-2-naphthylamide homo sapiens 18.8 18.8 1 PMID:12196024 -2.3.2.5 l-glutaminyl-4-methylcoumarinylamide homo sapiens 5.4 5.4 1 PMID:12196024 -2.3.2.5 l-glutaminyl-7-amido-4-methylcoumarin drosophila melanogaster 7.0 4.545 2 PMID:17722885 -2.3.2.5 l-glutaminyl-7-amido-4-methylcoumarin homo sapiens 1.07 1.07 1 PMID:19804409 -2.3.2.5 l-glutaminyl-7-amido-4-methylcoumarin mus musculus 6.98 6.98 1 PMID:19804409 -2.3.2.5 l-glutaminyl-beta-naphthylamide homo sapiens 3.4 3.4 1 PMID:19804409 -2.3.2.5 l-glutaminyl-beta-naphthylamide mus musculus 17.48 17.48 1 PMID:19804409 -2.3.2.5 n1-naphthalen-2-yl-l-glutamamide carica papaya 47.2 47.2 1 PMID:14719800 -2.3.2.5 n1-naphthalen-2-yl-l-glutamamide homo sapiens 20.0 20.0 1 PMID:14719800 -2.3.2.5 nepsilon-(l-gamma-glutamyl)-d-lysine oryctolagus cuniculus 0.25 0.25 1 PMID:22120669 -2.3.2.5 nepsilon-(l-gamma-glutamyl)-l-lysine oryctolagus cuniculus 0.2 0.2 1 PMID:22120669 -2.3.2.5 o-(n-butylcarbamyl)-l-serine oryctolagus cuniculus 12.0 12.0 1 PMID:22120669 -2.3.2.5 qaae myxococcus xanthus 40.0 40.0 1 PMID:20868223 -2.3.2.5 qaae zymomonas mobilis 0.054 0.054 1 PMID:20868223 -2.3.2.5 qaaf myxococcus xanthus 183.0 183.0 1 PMID:20868223 -2.3.2.5 qaaf zymomonas mobilis 8e-05 8e-05 1 PMID:20868223 -2.3.2.5 qaar myxococcus xanthus 170.0 170.0 1 PMID:20868223 -2.3.2.5 qaea myxococcus xanthus 40.0 40.0 1 PMID:20868223 -2.3.2.5 qaea zymomonas mobilis 0.0042 0.0042 1 PMID:20868223 -2.3.2.5 qafa myxococcus xanthus 102.0 102.0 1 PMID:20868223 -2.3.2.5 qafa zymomonas mobilis 0.0064 0.0064 1 PMID:20868223 -2.3.2.5 qara myxococcus xanthus 129.0 129.0 1 PMID:20868223 -2.3.2.5 qara zymomonas mobilis 0.0032 0.0032 1 PMID:20868223 -2.3.2.5 qeaa myxococcus xanthus 17.9 17.9 1 PMID:20868223 -2.3.2.5 qeaa zymomonas mobilis 0.007 0.007 1 PMID:20868223 -2.3.2.5 qedl homo sapiens 6.4 6.4 1 PMID:19804409 -2.3.2.5 qedl mus musculus 6.4 6.4 1 PMID:19804409 -2.3.2.5 qeyf homo sapiens 3.3 3.3 1 PMID:19804409 -2.3.2.5 qeyf mus musculus 11.78 11.78 1 PMID:19804409 -2.3.2.5 qfaa myxococcus xanthus 60.0 60.0 1 PMID:20868223 -2.3.2.5 qfaa zymomonas mobilis 0.084 0.084 1 PMID:20868223 -2.3.2.5 qfrh-nh2 carica papaya 42.0 42.0 1 PMID:19921850 -2.3.2.5 qfrh-nh2 homo sapiens 30.0 30.0 1 PMID:19921850 -2.3.2.5 qfrh-nh2 mus musculus 40.0 40.0 1 PMID:19921850 -2.3.2.5 qfrh-nh2 solanum tuberosum 56.0 56.0 1 PMID:19921850 -2.3.2.5 qggg myxococcus xanthus 1.1 1.1 1 PMID:20868223 -2.3.2.5 qggg zymomonas mobilis 0.012 0.012 1 PMID:20868223 -2.3.2.5 qraa myxococcus xanthus 66.0 66.0 1 PMID:20868223 -2.3.2.5 qraa zymomonas mobilis 0.0074 0.0074 1 PMID:20868223 -2.3.2.5 qsrnrtyeay porphyromonas gingivalis 13.3 13.3 1 PMID:33837744 -2.3.2.5 qsvvpdsigr porphyromonas gingivalis 7.0 7.0 1 PMID:33837744 -2.3.2.5 s-(cyclohexylamine)-l-cysteine oryctolagus cuniculus 0.26 0.26 1 PMID:22120669 -2.3.2.5 s-(n-butylcarbamyl)-l-cysteine oryctolagus cuniculus 0.27 0.27 1 PMID:22120669 -2.3.2.5 s-(n-propylcarbamyl)-l-cysteine oryctolagus cuniculus 0.24 0.24 1 PMID:22120669 -2.3.2.6 kac-acrydonylalanine escherichia coli 0.25 0.25 1 PMID:23905007 -2.3.2.6 kpc-acrydonylalanine escherichia coli 0.8 0.8 1 PMID:23905007 -2.3.2.6 kqc-acrydonylalanine escherichia coli 0.5 0.5 1 PMID:23905007 -2.3.2.6 l-leucyl-trnaleu escherichia coli 0.002 0.002 1 PMID:24935875 -2.3.2.6 l-phenylalanyl-trnaphe escherichia coli 0.00052 0.00052 1 PMID:24935875 -2.3.2.6 repglctwqslr escherichia coli 0.00367 0.0030800000000000003 4 PMID:19186990 -2.3.2.6 rgpcrafi escherichia coli 1.0 1.0 1 PMID:23905007 -2.3.2.8 l-arginyl-trna saccharomyces cerevisiae 0.0667 0.0667 1 PMID:7819189 -2.3.3.1 acetyl-coa cyanidioschyzon merolae 134.2 112.9 4 PMID:36884198 -2.3.3.1 acetyl-coa homo sapiens 260.0 260.0 2 PMID:31141475 -2.3.3.1 oxaloacetate cyanidioschyzon merolae 123.6 107.9 4 PMID:36884198 -2.3.3.1 oxaloacetate homo sapiens 208.0 208.0 2 PMID:31141475 -2.3.3.1 oxaloacetate sus scrofa 167.0 167.0 1 PMID:7577912 -2.3.3.10 acetyl-coa bos taurus 0.0417 0.0417 1 PMID:2860895 -2.3.3.10 acetyl-coa brassica juncea 0.415 0.415 1 PMID:15233626 -2.3.3.10 acetyl-coa gallus gallus 0.0667 0.0667 1 PMID:10727229 -2.3.3.10 acetyl-coa haloferax volcanii 4.6 4.6 1 PMID:23794621 -2.3.3.13 2-oxo-3-methylbutanoate arabidopsis thaliana 2.4 2.3499999999999996 4 PMID:17189332 -2.3.3.13 2-oxo-3-methylbutanoate mycobacterium tuberculosis 3.5 3.2 7 PMID:16684501;PMID:16846242;PMID:22352945 -2.3.3.13 2-oxo-3-methylbutanoate neisseria meningitidis 13.0 13.0 1 PMID:22352945 -2.3.3.13 2-oxo-butanoate mycobacterium tuberculosis 10.7 10.7 1 PMID:16846242 -2.3.3.13 2-oxo-n-pentanoate mycobacterium tuberculosis 7.0 7.0 1 PMID:16846242 -2.3.3.13 2-oxobutanoate malus domestica 0.39 0.39 1 PMID:33431667 -2.3.3.13 2-oxoisovalerate solanum lycopersicum 1.08 0.785 2 PMID:25986128 -2.3.3.13 3-fluoropyruvate neisseria meningitidis 105.0 105.0 1 PMID:20117081 -2.3.3.13 3-methyl-2-oxobutanoate brassica juncea 24.22 20.445 4 PMID:39869449 -2.3.3.13 3-methyl-2-oxobutanoate methanocaldococcus jannaschii 450.0 330.0 3 PMID:24720347;PMID:24991690 -2.3.3.13 3-methyl-2-oxobutanoate mycobacterium tuberculosis 3.7 3.7 1 PMID:23500460 -2.3.3.13 3-methyl-2-oxobutanoate saccharomyces cerevisiae 13.79 10.535 2 PMID:25841022 -2.3.3.13 3-methyl-2-oxobutanoate thermus thermophilus 1.2 1.2 1 PMID:29738774 -2.3.3.13 3-methyl-2-oxopentanoate neisseria meningitidis 0.28 0.28 1 PMID:20117081 -2.3.3.13 4-methylthio-2-oxobutyrate solanum lycopersicum 0.12 0.12 1 PMID:25986128 -2.3.3.13 acetyl-coa arabidopsis thaliana 2.2 2.05 4 PMID:17189332 -2.3.3.13 acetyl-coa brassica juncea 42.07 20.895000000000003 4 PMID:39869449 -2.3.3.13 acetyl-coa malus domestica 0.5 0.41500000000000004 2 PMID:33431667 -2.3.3.13 acetyl-coa methanocaldococcus jannaschii 450.0 390.0 2 PMID:24991690 -2.3.3.13 acetyl-coa mycobacterium tuberculosis 7.6 2.22 11 PMID:16846242;PMID:19166329;PMID:19505340;PMID:22352945;PMID:25064783 -2.3.3.13 acetyl-coa neisseria meningitidis 13.0 13.0 1 PMID:22352945 -2.3.3.13 acetyl-coa thermus thermophilus 1.7 1.7 1 PMID:29738774 -2.3.3.13 alpha-ketobutyrate neisseria meningitidis 1.36 1.36 1 PMID:20117081 -2.3.3.13 alpha-ketoisovalerate mycobacterium tuberculosis 2.53 2.53 1 PMID:19166329 -2.3.3.13 alpha-ketoisovalerate neisseria meningitidis 0.035 0.035 1 PMID:20117081 -2.3.3.13 alpha-ketoisovaleric acid mycobacterium tuberculosis 1.17 0.845 2 PMID:19505340 -2.3.3.13 crotonyl-coa mycobacterium tuberculosis 0.05 0.045 2 PMID:16846242 -2.3.3.13 propionyl-coa mycobacterium tuberculosis 0.04 0.04 1 PMID:16846242 -2.3.3.13 pyruvate malus domestica 0.22 0.22 1 PMID:33431667 -2.3.3.13 pyruvate mycobacterium tuberculosis 6.1 6.1 1 PMID:16846242 -2.3.3.13 pyruvate neisseria meningitidis 1.5 1.5 1 PMID:20117081 -2.3.3.14 2-oxoglutarate saccharomyces cerevisiae 0.617 0.45199999999999996 2 PMID:14984204;PMID:33990312 -2.3.3.14 2-oxoglutarate schizosaccharomyces pombe 5.133 5.1315 2 PMID:19776021;PMID:20089861 -2.3.3.14 2-oxoglutarate sulfolobus acidocaldarius 1.4 1.4 2 PMID:31330039;PMID:32897601 -2.3.3.14 2-oxoglutarate thermus thermophilus 0.182 0.182 1 PMID:19996101 -2.3.3.14 acetyl-coa aspergillus fumigatus 0.68 0.68 1 PMID:20363898 -2.3.3.14 acetyl-coa candida albicans 0.2 0.2 2 PMID:26363118 -2.3.3.14 acetyl-coa saccharomyces cerevisiae 0.617 0.443 2 PMID:14984204;PMID:33990312 -2.3.3.14 acetyl-coa schizosaccharomyces pombe 4.983 4.9815000000000005 2 PMID:19776021;PMID:20089861 -2.3.3.14 acetyl-coa sulfolobus acidocaldarius 1.3 1.3 2 PMID:31330039;PMID:32897601 -2.3.3.14 acetyl-coa thermus thermophilus 1.53 0.967 3 PMID:12095615;PMID:19996101 -2.3.3.14 oxaloacetate thermus thermophilus 0.967 0.967 1 PMID:12095615 -2.3.3.16 acetyl-coa acinetobacter calcoaceticus subsp. anitratus 78.0 78.0 1 PMID:1524432 -2.3.3.16 acetyl-coa arthrobacter sp. 18.0 18.0 1 PMID:11707611 -2.3.3.16 acetyl-coa azotobacter vinelandii 174.0 174.0 1 PMID:7819205 -2.3.3.16 acetyl-coa escherichia coli 81.0 44.0 5 PMID:12824188;PMID:1524432;PMID:23954305;PMID:32497258;PMID:32569710 -2.3.3.16 acetyl-coa geobacter sulfurreducens 8.8 8.55 2 PMID:16000798 -2.3.3.16 acetyl-coa leishmania donovani 0.97 0.97 1 PMID:39245106 -2.3.3.16 acetyl-coa metallosphaera sedula 8.56 8.535 2 PMID:30611567;PMID:30794680 -2.3.3.16 acetyl-coa microcystis aeruginosa 17.1 17.1 1 PMID:31755935 -2.3.3.16 acetyl-coa nostoc sp. pcc 7120 = fachb-418 23.0 23.0 1 PMID:31887428 -2.3.3.16 acetyl-coa rhodothermus marinus 22.0 21.5 2 PMID:11878562 -2.3.3.16 acetyl-coa saccharomyces cerevisiae 11.2 11.2 1 PMID:17570335 -2.3.3.16 acetyl-coa streptomyces diastaticus 262.8 262.8 1 PMID:25783416 -2.3.3.16 acetyl-coa sus scrofa 167.0 167.0 1 PMID:10694395 -2.3.3.16 acetyl-coa synechocystis sp. pcc 6803 2.99 2.51 3 PMID:30988396 -2.3.3.16 acetyl-coa thermoplasma acidophilum 9.8 9.184999999999999 4 PMID:10694395;PMID:10964687;PMID:15683225;PMID:19645419 -2.3.3.16 citrate acinetobacter calcoaceticus subsp. anitratus 942.0 942.0 1 PMID:4211224 -2.3.3.16 citrate azotobacter vinelandii 2100.0 2100.0 1 PMID:4211224 -2.3.3.16 citrate sus scrofa 117.0 117.0 1 PMID:10694395 -2.3.3.16 citrate thermoplasma acidophilum 11.4 10.285 2 PMID:10694395;PMID:15683225 -2.3.3.16 oxaloacetate azotobacter vinelandii 170.0 140.5 2 PMID:7819205 -2.3.3.16 oxaloacetate escherichia coli 114.0 89.0 5 PMID:12824188;PMID:30974512 -2.3.3.16 oxaloacetate geobacter sulfurreducens 8.8 8.55 2 PMID:16000798 -2.3.3.16 oxaloacetate leishmania donovani 0.75 0.75 1 PMID:39245106 -2.3.3.16 oxaloacetate metallosphaera sedula 7.62 7.27 2 PMID:30611567;PMID:30794680 -2.3.3.16 oxaloacetate microcystis aeruginosa 24.5 24.5 1 PMID:31755935 -2.3.3.16 oxaloacetate nostoc sp. pcc 7120 = fachb-418 31.9 31.9 1 PMID:31887428 -2.3.3.16 oxaloacetate streptomyces diastaticus 230.7 230.7 1 PMID:25783416 -2.3.3.16 oxaloacetate synechocystis sp. pcc 6803 3.35 2.76 3 PMID:30988396 -2.3.3.16 oxaloacetate thermoplasma acidophilum 9.2 9.2 1 PMID:19645419 -2.3.3.16 propionyl-coa arthrobacter sp. 8.0 8.0 1 PMID:11707611 -2.3.3.16 propionyl-coa rhodothermus marinus 12.0 12.0 1 PMID:11878562 -2.3.3.17 2-oxoisovalerate arabidopsis thaliana 0.18 0.18 1 PMID:17369439 -2.3.3.17 4-methylthio-2-oxobutanoate arabidopsis thaliana 1.3 1.3 1 PMID:17369439 -2.3.3.17 4-methylthio-2-oxobutanoate brassica juncea 0.11 0.11 1 PMID:39155114 -2.3.3.17 4-methylthio-2-oxobutanoic acid brassica juncea 0.116 0.1125 2 PMID:39322014 -2.3.3.17 5-methylthio-2-oxopentanoate arabidopsis thaliana 1.3 1.3 1 PMID:17369439 -2.3.3.17 6-methylthio-2-oxohexanoate arabidopsis thaliana 2.5 2.5 1 PMID:17369439 -2.3.3.17 8-methylthio-2-oxooctanoate arabidopsis thaliana 0.3 0.3 1 PMID:17369439 -2.3.3.17 9-methylthio-2-oxononanoate arabidopsis thaliana 0.03 0.03 1 PMID:17369439 -2.3.3.17 acetyl-coa arabidopsis thaliana 3.0 3.0 1 PMID:17369439 -2.3.3.17 acetyl-coa brassica juncea 0.47 0.1225 6 PMID:39155114;PMID:39322014 -2.3.3.17 pyruvate arabidopsis thaliana 0.17 0.17 1 PMID:17369439 -2.3.3.18 acetyl-coa streptomyces hygroscopicus 6.7 6.7 1 PMID:32697946 -2.3.3.18 oxaloacetate streptomyces hygroscopicus 6.7 6.7 1 PMID:32697946 -2.3.3.21 2-oxobutanoate malus domestica 0.39 0.39 1 PMID:33431667 -2.3.3.21 2-oxobutyrate leptospira interrogans 0.09 0.09 2 PMID:18498255 -2.3.3.21 acetyl-coa leptospira interrogans 11.1 10.3 10 PMID:18498255;PMID:19351325 -2.3.3.21 acetyl-coa malus domestica 0.5 0.41500000000000004 2 PMID:33431667 -2.3.3.21 acetyl-coa methanocaldococcus jannaschii 0.36 0.36 1 PMID:18952866 -2.3.3.21 glyoxylate leptospira interrogans 0.51 0.51 2 PMID:18498255 -2.3.3.21 pyruvate leptospira interrogans 9.3 9.1 12 PMID:15292141;PMID:18498255;PMID:19351325 -2.3.3.21 pyruvate malus domestica 0.22 0.22 1 PMID:33431667 -2.3.3.21 pyruvate methanocaldococcus jannaschii 0.36 0.36 2 PMID:18952866 -2.3.3.5 acetyl-coa aspergillus fumigatus 32.7 32.7 1 PMID:31141475 -2.3.3.5 acetyl-coa eimeria tenella 3.91 3.91 1 PMID:38704976 -2.3.3.5 acetyl-coa fusarium solani 15.5 15.5 1 PMID:19661181 -2.3.3.5 acetyl-coa fusarium verticillioides 29.9 29.9 1 PMID:19661181 -2.3.3.5 acetyl-coa salmonella enterica subsp. enterica serovar typhimurium 1.87 1.87 1 PMID:20970504 -2.3.3.5 oxaloacetate aspergillus fumigatus 29.2 29.2 1 PMID:31141475 -2.3.3.5 oxaloacetate aspergillus nidulans 23.0 23.0 1 PMID:10712680 -2.3.3.5 oxaloacetate eimeria tenella 3.91 3.91 1 PMID:38704976 -2.3.3.5 propanoyl-coa aspergillus fumigatus 30.1 30.1 1 PMID:31141475 -2.3.3.5 propanoyl-coa aspergillus nidulans 23.0 23.0 1 PMID:10712680 -2.3.3.5 propanoyl-coa eimeria tenella 3.91 3.91 1 PMID:38704976 -2.3.3.5 propanoyl-coa salmonella enterica subsp. enterica serovar typhimurium 8.25 8.25 1 PMID:20970504 -2.3.3.5 propionyl-coa fusarium solani 15.9 15.9 1 PMID:19661181 -2.3.3.5 propionyl-coa fusarium verticillioides 12.5 12.5 1 PMID:19661181 -2.3.3.9 acetyl-coa bacillus sp. (in: firmicutes) 27.8 27.8 1 PMID:6444795 -2.3.3.9 acetyl-coa colwellia maris 161.0 110.85 2 PMID:11440123 -2.3.3.9 acetyl-coa geobacillus stearothermophilus 26.7 26.7 1 PMID:236948 -2.3.3.9 acetyl-coa mycobacterium tuberculosis 23.0 23.0 1 PMID:21728344 -2.3.3.9 glyoxylate escherichia coli 48.1 48.1 1 PMID:12930982 -2.3.3.9 glyoxylate euglena gracilis 17.0 15.5 2 PMID:21332878 -2.3.3.9 glyoxylate mycobacterium tuberculosis 23.0 23.0 1 PMID:21728344 -2.4.1.1 alpha-d-glucose 1-phosphate acetivibrio thermocellus 4.2 4.2 1 * -2.4.1.1 alpha-d-glucose 1-phosphate corynebacterium callunae 52.0 52.0 1 PMID:15535798 -2.4.1.1 alpha-d-xylose 1-phosphate corynebacterium callunae 0.0026 0.0026 1 PMID:15535798 -2.4.1.1 arsenate corynebacterium callunae 4.9 4.9 1 PMID:9307027 -2.4.1.1 d-glucose-1-phosphate solanum tuberosum 0.001 0.001 1 PMID:16151135 -2.4.1.1 dextrin dp11 corynebacterium callunae 187.0 118.5 2 PMID:9307027 -2.4.1.1 dextrin dp14 acetivibrio thermocellus 9.3 6.45 2 * -2.4.1.1 dextrin dp19 acetivibrio thermocellus 8.1 7.35 2 * -2.4.1.1 dextrin dp4 acetivibrio thermocellus 11.0 9.7 2 * -2.4.1.1 dextrin dp9 corynebacterium callunae 47.3 47.3 1 PMID:9307027 -2.4.1.1 glucose 1-phosphate corynebacterium callunae 131.0 131.0 1 PMID:9307027 -2.4.1.1 glycogen dp14 corynebacterium callunae 283.0 158.75 2 PMID:9307027 -2.4.1.1 maltoheptaose aquifex aeolicus 4.4 3.35 2 * -2.4.1.1 maltoheptaose corynebacterium callunae 312.0 176.65 2 PMID:9307027 -2.4.1.1 maltohexaose aquifex aeolicus 4.1 3.4 2 * -2.4.1.1 maltohexaose corynebacterium callunae 38.9 38.9 1 PMID:9307027 -2.4.1.1 maltopentaose aquifex aeolicus 5.4 3.8000000000000003 2 * -2.4.1.1 maltopentaose corynebacterium callunae 33.8 16.9165 2 PMID:17803683;PMID:9307027 -2.4.1.1 maltose sulfurisphaera tokodaii str. 7 15.2 15.2 1 * -2.4.1.1 maltotetraose aquifex aeolicus 6.0 3.38 2 * -2.4.1.1 maltotetraose solanum tuberosum 0.0037 0.0037 1 PMID:16151135 -2.4.1.1 maltotetraose sulfurisphaera tokodaii str. 7 34.6 17.38 2 * -2.4.1.1 maltotriose aquifex aeolicus 6.8 6.8 1 * -2.4.1.1 maltotriose sulfurisphaera tokodaii str. 7 24.8 12.43 2 * -2.4.1.1 phosphate acetivibrio thermocellus 8.2 8.2 1 * -2.4.1.1 phosphate corynebacterium callunae 50.5 48.75 2 PMID:20113461;PMID:9307027 -2.4.1.1 phosphate saccharolobus solfataricus 2.1 2.1 1 PMID:19682609 -2.4.1.1 starch acetivibrio thermocellus 6.3 4.2 2 * -2.4.1.1 starch corynebacterium callunae 74.0 71.95 2 PMID:15535798;PMID:9307027 -2.4.1.1 starch sulfurisphaera tokodaii str. 7 19.4 9.799999999999999 2 * -2.4.1.1 starch dp24 corynebacterium callunae 300.0 300.0 1 PMID:9307027 -2.4.1.10 sucrose aspergillus tamarii 0.117 0.117 1 PMID:31269326 -2.4.1.10 sucrose bacillus amyloliquefaciens 729.0 358.5 4 * -2.4.1.10 sucrose bacillus licheniformis 672.38 117.0 8 PMID:31437510;PMID:32439436 -2.4.1.10 sucrose bacillus subtilis 236.7 69.8 11 PMID:18596022;PMID:28962785;PMID:32553967;PMID:33303628 -2.4.1.10 sucrose beijerinckia indica subsp. indica 12000.0 9000.0 3 * -2.4.1.10 sucrose erwinia amylovora 502.7 502.7 1 PMID:30660564 -2.4.1.10 sucrose erwinia tasmaniensis 497.9 497.9 1 PMID:30660564 -2.4.1.10 sucrose gluconacetobacter diazotrophicus 1.0 0.50195 2 PMID:15869470 -2.4.1.10 sucrose gluconobacter oxydans 600000.0 300000.0 3 * -2.4.1.10 sucrose leuconostoc mesenteroides 1500.0 1500.0 1 * -2.4.1.10 sucrose novosphingobium aromaticivorans 317400.0 176000.0 3 * -2.4.1.10 sucrose paraburkholderia graminis 7200.0 5700.0 3 * -2.4.1.10 sucrose priestia megaterium 2272.0 222.92 13 PMID:17608626;PMID:40023420 -2.4.1.10 sucrose pseudomonas chlororaphis subsp. aurantiaca 7.2 7.2 1 PMID:25644638 -2.4.1.10 sucrose pseudomonas orientalis 620.0 620.0 1 PMID:36987215 -2.4.1.10 sucrose pseudomonas syringae pv. tomato 504.4 416.35 2 PMID:25644638 -2.4.1.10 sucrose streptococcus salivarius 55400.0 33600.0 3 * -2.4.1.10 sucrose vibrio natriegens 200000.0 200000.0 3 * -2.4.1.10 sucrose zymomonas mobilis 461.0 395.0 4 PMID:12359071;PMID:18809687 -2.4.1.115 cyanidin vitis labrusca 0.000704 0.000704 1 PMID:22098678 -2.4.1.115 kaempferol glycine max 1.25 1.25 1 PMID:20621794 -2.4.1.115 quercetin vitis labrusca 0.000113 0.000113 1 PMID:22098678 -2.4.1.115 udp-glucose vitis labrusca 0.000247 0.000247 1 PMID:22098678 -2.4.1.12 udp-alpha-d-glucose novacetimonas hansenii 2.9 2.9 1 PMID:27214134 -2.4.1.120 sinapate daucus carota 0.04 0.04 1 PMID:27171142 -2.4.1.120 sinapate daucus carota subsp. sativus 0.04 0.04 1 PMID:27171142 -2.4.1.121 (indol-3-yl)acetate arabidopsis thaliana 0.0017 0.0017 1 PMID:32868079 -2.4.1.121 (indol-3-yl)acetate lathyrus oleraceus 2.27 2.27 1 PMID:26057226 -2.4.1.121 (indol-3-yl)propionate lathyrus oleraceus 0.72 0.72 1 PMID:26057226 -2.4.1.121 1-naphthalene acetate lathyrus oleraceus 0.53 0.53 1 PMID:26057226 -2.4.1.121 phenylacetic acid arabidopsis thaliana 0.0147 0.0147 1 PMID:32868079 -2.4.1.121 udp-glucose lathyrus oleraceus 0.49 0.49 1 PMID:26057226 -2.4.1.128 carvacrol nicotiana benthamiana 0.967 0.889 2 PMID:31124249 -2.4.1.128 kaempferol nicotiana benthamiana 0.589 0.46499999999999997 2 PMID:31124249 -2.4.1.128 n-4-trans-coumaroyl tyramine nicotiana benthamiana 0.01 0.01 1 PMID:31124249 -2.4.1.128 n-caffeoyl-o-methyl tyramine nicotiana benthamiana 0.07 0.065 2 PMID:31124249 -2.4.1.128 n-trans-feruloyl tyramine nicotiana benthamiana 0.06 0.06 1 PMID:31124249 -2.4.1.128 quercetin nicotiana benthamiana 0.65 0.457 2 PMID:31124249 -2.4.1.128 scopoletin arabidopsis thaliana 10.92 1.11 4 PMID:18295607 -2.4.1.128 scopoletin nicotiana benthamiana 0.916 0.841 2 PMID:31124249 -2.4.1.13 adp acidithiobacillus caldus 97.1 97.1 1 PMID:26657050 -2.4.1.13 adp arabidopsis thaliana 450.0 450.0 1 PMID:26657050 -2.4.1.13 adp glycine max 2.07 2.07 1 PMID:26657050 -2.4.1.13 adp hordeum vulgare 285.0 285.0 1 PMID:26657050 -2.4.1.13 adp manihot esculenta 9.8 9.8 1 PMID:26657050 -2.4.1.13 adp nitrosomonas europaea 31.9 31.9 1 PMID:26657050 -2.4.1.13 adp pyrus pyrifolia 3.9 2.5 2 PMID:26657050 -2.4.1.13 adp solanum tuberosum 99.7 99.7 1 PMID:26657050 -2.4.1.13 adp thermosynechococcus vestitus 2.0 2.0 1 PMID:26657050 -2.4.1.13 adp vicia faba 0.77 0.77 1 PMID:26657050 -2.4.1.13 adp-alpha-d-glucose glycine max 2.9 2.9 1 PMID:26657050 -2.4.1.13 adp-alpha-d-glucose manihot esculenta 9.8 9.8 1 PMID:26657050 -2.4.1.13 adp-alpha-d-glucose nitrosomonas europaea 5.7 5.7 1 PMID:26657050 -2.4.1.13 adp-alpha-d-glucose oryza sativa 22.2 22.2 1 PMID:26657050 -2.4.1.13 adp-alpha-d-glucose pyrus pyrifolia 2.7 2.45 2 PMID:26657050 -2.4.1.13 adp-alpha-d-glucose thermosynechococcus vestitus 1.7 1.7 1 PMID:26657050 -2.4.1.13 d-fructose arabidopsis thaliana 18.6 14.25 4 PMID:26657050 -2.4.1.13 d-fructose glycine max 21.5 21.5 1 PMID:26657050 -2.4.1.13 d-fructose manihot esculenta 4.2 3.25 2 PMID:26657050 -2.4.1.13 d-fructose nitrosomonas europaea 7.4 5.85 2 PMID:26657050 -2.4.1.13 d-fructose oryza sativa 25.7 18.75 2 PMID:26657050 -2.4.1.13 d-fructose pyrus pyrifolia 18.7 9.7 2 PMID:26657050 -2.4.1.13 d-fructose solanum tuberosum 0.32 0.32 1 PMID:26657050 -2.4.1.13 d-fructose thermosynechococcus vestitus 2.9 2.0 2 PMID:26657050 -2.4.1.13 d-fructose vigna radiata 0.13 0.13 1 PMID:26657050 -2.4.1.13 sucrose arabidopsis thaliana 907.0 450.0 3 PMID:26657050 -2.4.1.13 sucrose beta vulgaris 6.1 6.1 2 PMID:26657050 -2.4.1.13 sucrose glycine max 20.0 20.0 1 PMID:26657050 -2.4.1.13 sucrose glycyrrhiza uralensis 87.1 69.15 2 PMID:31558015 -2.4.1.13 sucrose hordeum vulgare 435.0 360.0 2 PMID:26657050 -2.4.1.13 sucrose manihot esculenta 4.9 4.25 2 PMID:26657050 -2.4.1.13 sucrose nicotiana tabacum 39.5 22.235 2 PMID:15120114 -2.4.1.13 sucrose nitrosomonas europaea 96.7 69.35 2 PMID:26657050 -2.4.1.13 sucrose oryza sativa 0.18 0.18 1 PMID:26657050 -2.4.1.13 sucrose pyrus pyrifolia 5.4 3.0500000000000003 2 PMID:26657050 -2.4.1.13 sucrose solanum tuberosum 122.0 99.7 3 PMID:26657050 -2.4.1.13 sucrose thermosynechococcus vestitus 6.0 6.0 1 PMID:23196182 -2.4.1.13 udp acidithiobacillus caldus 82.0 82.0 1 PMID:26657050 -2.4.1.13 udp arabidopsis thaliana 907.0 457.15 2 PMID:26657050 -2.4.1.13 udp beta vulgaris 6.1 6.1 2 PMID:26657050 -2.4.1.13 udp denitrovibrio acetiphilus 8.67 8.67 1 PMID:40090494 -2.4.1.13 udp glycine max 20.0 20.0 1 PMID:26657050 -2.4.1.13 udp glycyrrhiza uralensis 74.8 68.4 2 PMID:31558015 -2.4.1.13 udp hordeum vulgare 435.0 435.0 1 PMID:26657050 -2.4.1.13 udp manihot esculenta 5.9 5.9 1 PMID:26657050 -2.4.1.13 udp micractinium conductrix 17.3 17.3 1 PMID:37649634 -2.4.1.13 udp nitrosomonas europaea 103.8 103.8 1 PMID:26657050 -2.4.1.13 udp nitrosospira multiformis 26.4 26.4 1 PMID:36795895 -2.4.1.13 udp oryza sativa 0.18 0.18 1 PMID:26657050 -2.4.1.13 udp pyrus pyrifolia 5.4 3.0500000000000003 2 PMID:26657050 -2.4.1.13 udp solanum tuberosum 122.7 61.45 2 PMID:26657050 -2.4.1.13 udp thermosynechococcus vestitus 3.5 3.5 1 PMID:26657050 -2.4.1.13 udp vicia faba 3.1 3.1 1 PMID:26657050 -2.4.1.13 udp-alpha-d-glucose arabidopsis thaliana 18.6 9.25 4 PMID:26657050 -2.4.1.13 udp-alpha-d-glucose glycine max 21.5 21.5 1 PMID:26657050 -2.4.1.13 udp-alpha-d-glucose manihot esculenta 9.8 9.8 1 PMID:26657050 -2.4.1.13 udp-alpha-d-glucose nitrosomonas europaea 6.7 6.7 1 PMID:26657050 -2.4.1.13 udp-alpha-d-glucose oryza sativa 10.5 10.5 1 PMID:26657050 -2.4.1.13 udp-alpha-d-glucose pyrus pyrifolia 18.1 9.4 2 PMID:26657050 -2.4.1.13 udp-alpha-d-glucose solanum tuberosum 0.34 0.34 1 PMID:26657050 -2.4.1.13 udp-alpha-d-glucose thermosynechococcus vestitus 4.6 4.6 1 PMID:26657050 -2.4.1.13 udp-alpha-d-glucose vigna radiata 0.13 0.13 1 PMID:26657050 -2.4.1.132 alpha-d-man-(1->3)-beta-d-man-(1->4)-beta-d-glcnac-(1->4)-alpha-d-glcnac-diphosphodolichol homo sapiens 0.0054 0.0054 1 PMID:35136180 -2.4.1.132 alpha-d-man-(1->6)-beta-d-man-(1->4)-beta-d-glcnac-(1->4)-alpha-d-glcnac-diphosphodolichol homo sapiens 0.0632 0.0632 1 PMID:35136180 -2.4.1.133 (1r,2s,3r,4r)-4-(2-naphthyloxy)cyclohexan-1,2,3-triol homo sapiens 2.7 2.7 1 PMID:29024190 -2.4.1.133 2-(6-hydroxynaphthyl) beta-d-xylopyranoside homo sapiens 152.0 152.0 1 PMID:21327212 -2.4.1.133 2-naphthyl 1,5-dithio-beta-d-xylopyranoside homo sapiens 1.6 1.6 1 PMID:29024190 -2.4.1.133 2-naphthyl 5-thio-beta-d-xylopyranoside homo sapiens 2.0 2.0 1 PMID:29024190 -2.4.1.133 3-acetamido-propyl beta-d-xylopyranoside homo sapiens 30.2 30.2 1 PMID:21327212 -2.4.1.133 3-benzamido-propyl beta-d-xylopyranoside homo sapiens 47.2 47.2 1 PMID:21327212 -2.4.1.133 3-hexanamido-propyl beta-d-xylopyranoside homo sapiens 41.0 41.0 1 PMID:21327212 -2.4.1.133 4-methylumbelliferyl-beta-d-xylopyranoside homo sapiens 4080.0 1.79 3 PMID:19032152;PMID:20843813;PMID:25568325 -2.4.1.133 4-nitrophenyl-beta-d-xylopyranoside homo sapiens 5460.0 5460.0 1 PMID:19032152 -2.4.1.133 n-[o-(beta-d-xylopyranosyl)-3-hydroxypropyl]phthalamate homo sapiens 78.7 78.7 1 PMID:21327212 -2.4.1.133 n-[o-(beta-d-xylopyranosyl)-3-hydroxypropyl]succinamate homo sapiens 64.3 64.3 1 PMID:21327212 -2.4.1.133 naphthalen-2-yl 1-thio-beta-d-xylopyranoside homo sapiens 2.7 2.7 1 PMID:29024190 -2.4.1.133 naphthalen-2-yl beta-d-xylopyranoside homo sapiens 3.1 3.1 1 PMID:29024190 -2.4.1.133 o-gamma-beta-d-xylopyranosyl-n-cbz-l-serine methyl ester homo sapiens 106.3 106.3 1 PMID:21327212 -2.4.1.133 udp-alpha-d-galactose homo sapiens 1.5 1.5 1 PMID:25568325 -2.4.1.133 udp-galactose homo sapiens 5086.0 1.125 6 PMID:19032152;PMID:20691685;PMID:20809901;PMID:20843813 -2.4.1.133 udp-glucose homo sapiens 72.0 72.0 1 PMID:19032152 -2.4.1.133 udp-xylose homo sapiens 6.0 6.0 1 PMID:19032152 -2.4.1.136 gallate eucalyptus camaldulensis 13.5 12.1 2 PMID:29775866 -2.4.1.136 protocatechuate eucalyptus camaldulensis 12.7 11.399999999999999 2 PMID:29775866 -2.4.1.136 vanillate eucalyptus camaldulensis 12.6 11.5 2 PMID:29775866 -2.4.1.140 sucrose leuconostoc citreum 815.6 552.8 2 PMID:29844508;PMID:33810084 -2.4.1.149 udp-n-acetyl-d-glucosamine homo sapiens 0.597 0.597 1 PMID:33158990 -2.4.1.15 d-glucose 6-phosphate microbacterium sediminis 58.46 58.46 1 PMID:31933418 -2.4.1.15 d-glucose 6-phosphate pleurotus ostreatus 5.89 5.89 1 PMID:28513878 -2.4.1.15 glucose 6-phosphate escherichia coli 6.7 4.95 2 PMID:10831428 -2.4.1.15 udp-alpha-d-glucose microbacterium sediminis 58.81 58.81 1 PMID:31933418 -2.4.1.15 udp-alpha-d-glucose pleurotus ostreatus 5.89 5.89 1 PMID:28513878 -2.4.1.15 udp-alpha-d-glucose sulfolobus acidocaldarius 4.9 4.9 1 PMID:33008820 -2.4.1.15 udpglucose escherichia coli 7.3 5.45 2 PMID:10831428 -2.4.1.152 d-lactose helicobacter pylori 2.25 2.25 1 PMID:26804479 -2.4.1.152 fucalpha(1,2)galbeta(1,4)glcnac homo sapiens 1.7 1.7 1 PMID:9737989 -2.4.1.152 galbeta1,4glcnac-o(ch2)8co2ch3 helicobacter pylori 2.3 1.7 2 PMID:16407247 -2.4.1.152 gdp-beta-fucose helicobacter pylori 0.617 0.33 2 PMID:31132553 -2.4.1.152 gdp-beta-l-fucose helicobacter pylori 2.3 1.1 3 PMID:16407247;PMID:26804479 -2.4.1.152 lactose helicobacter pylori 0.02 0.02 1 PMID:31132553 -2.4.1.152 n-acetyllactosamine helicobacter pylori 0.367 0.367 1 PMID:31132553 -2.4.1.17 entacapone homo sapiens 0.422 0.037849999999999995 4 PMID:30111624 -2.4.1.17 morphine homo sapiens 0.138 0.07650000000000001 2 PMID:30111624 -2.4.1.170 calycosin astragalus membranaceus 0.059 0.04095 2 PMID:37604680 -2.4.1.170 daidzein glycine max 5.89 1.22 5 PMID:26019269 -2.4.1.170 daidzein pueraria montana var. lobata 1.1 1.1 1 PMID:24700248 -2.4.1.170 genistein glycine max 6.04 0.75 8 PMID:17565994;PMID:26019269 -2.4.1.170 genistein pueraria montana var. lobata 1.1 1.1 1 PMID:24700248 -2.4.1.170 udp-glucose glycine max 8.79 1.72 5 PMID:26019269 -2.4.1.173 24-methylene cholesterol withania somnifera 0.38 0.38 1 PMID:17293176 -2.4.1.173 3-beta-hydroxy-pregna-5,16-dien-20-one withania somnifera 0.0093 0.0093 1 PMID:17293176 -2.4.1.173 beta-sitosterol withania somnifera 0.0037 0.0037 1 PMID:17293176 -2.4.1.173 cholesterol kluyveromyces lactis 475.0 475.0 1 PMID:24056940 -2.4.1.173 cholesterol ogataea angusta 650.6 650.6 1 PMID:24056940 -2.4.1.173 dehydroepiandrosterone withania somnifera 0.0072 0.0072 1 PMID:17293176 -2.4.1.173 diosgenin withania somnifera 0.0023 0.0023 1 PMID:17293176 -2.4.1.173 pennogenin-3-o-rhamnosyl-(1->2)-glucoside paris polyphylla var. yunnanensis 0.002 0.002 1 PMID:38851474 -2.4.1.173 pregnenolone withania somnifera 0.0047 0.0047 1 PMID:17293176 -2.4.1.173 stigmasterol withania somnifera 0.0088 0.0088 1 PMID:17293176 -2.4.1.173 testosterone ogataea angusta 351.9 351.9 1 PMID:24056940 -2.4.1.173 udp-glucose withania somnifera 0.0087 0.0087 1 PMID:17293176 -2.4.1.175 udp-galnac avibacterium paragallinarum 355.0 355.0 1 PMID:29610966 -2.4.1.177 4-hydroxybenzoate fragaria x ananassa 2.0 1.25 2 PMID:26884604 -2.4.1.177 gallate fragaria vesca 1.1 1.1 1 PMID:26884604 -2.4.1.177 gallate fragaria x ananassa 0.8 0.8 1 PMID:26884604 -2.4.1.177 gallate rubus idaeus 1.6 1.6 1 PMID:26884604 -2.4.1.177 sinapate fragaria x ananassa 1.2 0.95 2 PMID:26884604 -2.4.1.177 syringate fragaria x ananassa 1.8 1.15 2 PMID:26884604 -2.4.1.177 udp-glucose fragaria vesca 2.2 2.2 1 PMID:26884604 -2.4.1.177 udp-glucose fragaria x ananassa 4.5 4.15 2 PMID:26884604 -2.4.1.177 udp-glucose rubus idaeus 6.6 6.6 1 PMID:26884604 -2.4.1.177 vanillate fragaria x ananassa 2.1 1.5 2 PMID:26884604 -2.4.1.18 amylose mycobacterium tuberculosis 0.15 0.15 1 PMID:20444687 -2.4.1.18 amylose solanum tuberosum 1000.0 1000.0 1 * -2.4.1.185 apigenin plagiochasma appendiculatum 0.0022 0.00165 2 PMID:32900434 -2.4.1.185 apigenin zea mays 0.99 0.99 1 PMID:39923422 -2.4.1.185 calycosin astragalus membranaceus 0.059 0.04095 2 PMID:37604680 -2.4.1.185 chrysin zea mays 0.73 0.73 1 PMID:39923422 -2.4.1.185 chrysoeriol zea mays 2.01 2.01 1 PMID:39923422 -2.4.1.185 diosmetin citrus sinensis 1.6 1.6 1 PMID:29497429 -2.4.1.185 eriodictyol zea mays 0.23 0.23 1 PMID:39923422 -2.4.1.185 hesperetin citrus sinensis 0.77 0.77 1 PMID:29497429 -2.4.1.185 isorhamnetin zea mays 1.3 1.3 1 PMID:39923422 -2.4.1.185 kaempferol citrus sinensis 0.46 0.46 1 PMID:29497429 -2.4.1.185 kaempferol zea mays 1.18 1.18 1 PMID:39923422 -2.4.1.185 luteolin plagiochasma appendiculatum 0.007 0.0046 2 PMID:32900434 -2.4.1.185 luteolin zea mays 0.95 0.95 1 PMID:39923422 -2.4.1.185 naringenin citrus sinensis 0.71 0.71 1 PMID:29497429 -2.4.1.185 naringenin lycium barbarum 0.89 0.89 1 * -2.4.1.185 naringenin zea mays 0.87 0.87 1 PMID:39923422 -2.4.1.185 quercetin citrus sinensis 0.58 0.58 1 PMID:29497429 -2.4.1.185 quercetin plagiochasma appendiculatum 0.029 0.02685 2 PMID:32900434 -2.4.1.185 quercetin zea mays 3.32 3.32 1 PMID:39923422 -2.4.1.186 udp-glucose oryctolagus cuniculus 0.0183 0.0083 4 PMID:16889748 -2.4.1.187 2-(acetylamino)-2-deoxy-1-o-(hydroxy[[hydroxy(tridecyloxy)phosphoryl]oxy]phosphoryl)-alpha-d-glucopyranose bacillus subtilis 9.183 5.5765 2 PMID:16953575 -2.4.1.187 2-(acetylamino)-2-deoxy-1-o-[[[[[(2z)-3,7-dimethylocta-2,6-dien-1-yl]oxy](hydroxy)phosphoryl]oxy](hydroxy)phosphoryl]-alpha-d-glucopyranose bacillus subtilis 6.08 3.473 2 PMID:16953575 -2.4.1.187 2-(acetylamino)-2-deoxy-1-o-[hydroxy[(hydroxy[[(2e,6e,10e)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl]oxy]phosphoryl)oxy]phosphoryl]-alpha-d-glucopyranose bacillus subtilis 10.25 10.25 1 PMID:16953575 -2.4.1.187 2-(acetylamino)-2-deoxy-1-o-[hydroxy[(hydroxy[[(2z,6z)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy]phosphoryl)oxy]phosphoryl]-alpha-d-glucopyranose bacillus subtilis 13.92 7.22 2 PMID:16953575 -2.4.1.187 2-(acetylamino)-2-deoxy-1-o-[hydroxy[(hydroxy[[(2z,6z,10z)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl]oxy]phosphoryl)oxy]phosphoryl]-alpha-d-glucopyranose bacillus subtilis 8.617 5.293500000000001 2 PMID:16953575 -2.4.1.19 3-ketobutylidene-beta-2-chloro-4-nitrophenylmaltopentaoside bacillus sp. (in: firmicutes) 4.07 3.725 2 PMID:8061001 -2.4.1.19 4,6-o-ethylidene-4-nitrophenyl alpha-d-maltoheptaoside thermoanaerobacterium thermosulfurigenes 1244.0 1244.0 1 PMID:18422488 -2.4.1.19 alpha-cyclodextrin bacillus sp. (in: firmicutes) 0.0442 0.0442 1 PMID:8061001 -2.4.1.19 beta-cyclodextrin bacillus sp. (in: firmicutes) 0.0095 0.0095 1 PMID:8061001 -2.4.1.19 cassava starch niallia circulans 1612.0 1612.0 1 * -2.4.1.19 gamma-cyclodextrin bacillus sp. 1011 4010.0 4010.0 1 PMID:39353521 -2.4.1.19 l-ascorbic acid paenibacillus macerans 9.7e-05 9.7e-05 1 PMID:23160123 -2.4.1.19 maltodextrin niallia circulans 768.0 585.5 4 PMID:26608005;PMID:29733932;PMID:33561459 -2.4.1.19 maltodextrin paenibacillus macerans 768.0 0.04245 4 PMID:23129181;PMID:23160123;PMID:32005733 -2.4.1.19 maltose geobacillus stearothermophilus 648.3 648.3 1 PMID:33837009 -2.4.1.19 maltose thermoanaerobacterium thermosulfurigenes 1244.0 1244.0 1 PMID:18422488 -2.4.1.19 p-nitrophenyl-(alpha-1,4-glucopyranosyl)2-d-glucose niallia circulans 1.66 1.66 1 * -2.4.1.19 p-nitrophenyl-(alpha-1,4-glucopyranosyl)3-d-glucose niallia circulans 0.833 0.833 1 * -2.4.1.19 p-nitrophenyl-(alpha-1,4-glucopyranosyl)4-d-glucose niallia circulans 0.833 0.833 1 * -2.4.1.19 p-nitrophenyl-(alpha-1,4-glucopyranosyl)5-d-glucose niallia circulans 0.833 0.833 1 * -2.4.1.19 p-nitrophenyl-(alpha-1,4-glucopyranosyl)6-d-glucose niallia circulans 0.833 0.833 1 * -2.4.1.19 p-nitrophenyl-(alpha-1,4-glucopyranosyl)7-d-glucose niallia circulans 0.25 0.25 1 * -2.4.1.19 rutin bacillus sp. 1011 1030.0 1030.0 1 PMID:39353521 -2.4.1.19 soluble corn starch bacillus sp. n-227 70.0 70.0 1 PMID:28597161 -2.4.1.19 soluble potato starch niallia circulans 803.0 524.6 2 PMID:21993482 -2.4.1.19 soluble potato starch paenibacillus barengoltzii 250.4 247.85000000000002 2 PMID:30690526 -2.4.1.19 soluble starch bacillus cereus 2.32 2.09 2 PMID:25709024 -2.4.1.19 soluble starch bacillus sp. (in: firmicutes) 3.13 3.13 1 PMID:22754298 -2.4.1.19 soluble starch geobacillus stearothermophilus 11.0 11.0 1 PMID:33837009 -2.4.1.19 soluble starch shouchella lehensis 405.77 404.33 2 PMID:35636531 -2.4.1.19 sophoricoside paenibacillus macerans 0.063 0.063 1 PMID:32005733 -2.4.1.19 starch bacillus sp. (in: firmicutes) 1.13 0.819 2 PMID:8061001 -2.4.1.19 starch cytobacillus firmus 2.42 2.42 1 PMID:10341434 -2.4.1.19 starch niallia circulans 329.0 329.0 1 PMID:18283101 -2.4.1.19 starch paenibacillus macerans 1.66 1.051 2 PMID:10420654 -2.4.1.19 starch thermococcus sp. 1.33 1.165 2 PMID:10548490 -2.4.1.20 1,5-anhydro-d-glucitol ruminococcus albus 2.8 2.8 1 PMID:22484959 -2.4.1.20 1,5-anhydroglucitol cellulomonas gilvus 3.5 3.5 1 PMID:16646954 -2.4.1.20 2-deoxy-2-fluoro-d-glucose cellulomonas uda 8.0 8.0 1 * -2.4.1.20 2-deoxy-d-glucose acetivibrio thermocellus 18.3 18.3 1 PMID:12153715 -2.4.1.20 2-deoxy-d-glucose cellulomonas uda 11.6 11.6 1 * -2.4.1.20 2-deoxy-d-glucose ruminococcus albus 21.5 21.5 2 PMID:22484959;PMID:23845516 -2.4.1.20 2-deoxy-d-glucose thermotoga maritima 16.0 16.0 1 PMID:12596851 -2.4.1.20 6-deoxy-6-fluoro-d-glucose cellulomonas uda 44.6 44.6 1 * -2.4.1.20 6-deoxy-d-glucose acetivibrio thermocellus 59.5 59.5 1 PMID:12153715 -2.4.1.20 6-deoxy-d-glucose cellulomonas uda 55.3 55.3 1 * -2.4.1.20 6-deoxy-d-glucose ruminococcus albus 124.0 124.0 1 PMID:22484959 -2.4.1.20 6-deoxy-d-glucose thermotoga maritima 17.0 17.0 1 PMID:12596851 -2.4.1.20 alpha-d-glucose 1-phosphate caldicellulosiruptor bescii 294.0 294.0 1 PMID:35273293 -2.4.1.20 alpha-d-glucose 1-phosphate cellulomonas uda 43.2 43.2 2 * -2.4.1.20 alpha-d-glucose 1-phosphate ruminococcus albus 92.3 92.3 1 PMID:23845516 -2.4.1.20 alpha-d-glucose 1-phosphate thermosipho africanus 7.61 7.61 1 PMID:28687766 -2.4.1.20 cellobiose acetivibrio thermocellus 7.09 2.785 4 PMID:22511238;PMID:37833899 -2.4.1.20 cellobiose caldicellulosiruptor bescii 18.4 18.4 1 PMID:35273293 -2.4.1.20 cellobiose cellulomonas uda 29.1 29.1 3 PMID:19487233 -2.4.1.20 cellobiose ruminococcus albus 79.1 79.1 1 PMID:23845516 -2.4.1.20 cellobiose thermoclostridium stercorarium 1.1 1.1 1 PMID:9249035 -2.4.1.20 cellobiose thermosipho africanus 0.23 0.23 1 PMID:28687766 -2.4.1.20 cellobiose thermotoga maritima 5.4 5.4 1 PMID:12596851 -2.4.1.20 cellobiose unidentified 8.83 8.83 1 * -2.4.1.20 cellopentaose thermosipho africanus 0.34 0.34 1 PMID:28687766 -2.4.1.20 cellotetraose thermosipho africanus 0.49 0.49 1 PMID:28687766 -2.4.1.20 cellotriose acetivibrio thermocellus 0.67 0.67 1 PMID:37833899 -2.4.1.20 cellotriose thermosipho africanus 0.28 0.28 1 PMID:28687766 -2.4.1.20 d-gentobiose ruminococcus albus 4.0 4.0 1 PMID:22484959 -2.4.1.20 d-glucosamine acetivibrio thermocellus 7.7 7.7 1 PMID:12153715 -2.4.1.20 d-glucosamine ruminococcus albus 9.56 9.56 2 PMID:22484959;PMID:23845516 -2.4.1.20 d-glucosamine thermotoga maritima 5.2 5.2 1 PMID:12596851 -2.4.1.20 d-glucose acetivibrio thermocellus 12.2 12.2 1 PMID:12153715 -2.4.1.20 d-glucose cellulomonas uda 43.2 27.5 3 * -2.4.1.20 d-glucose ruminococcus albus 92.3 92.3 1 PMID:22484959 -2.4.1.20 d-glucose thermosipho africanus 30.3 30.3 1 PMID:28687766 -2.4.1.20 d-glucose thermotoga maritima 8.0 8.0 1 PMID:12596851 -2.4.1.20 d-glucoseamine cellulomonas uda 5.6 5.6 1 * -2.4.1.20 d-mannose acetivibrio thermocellus 9.3 9.3 1 PMID:12153715 -2.4.1.20 d-mannose cellulomonas uda 6.6 6.6 1 * -2.4.1.20 d-mannose ruminococcus albus 2.83 2.83 2 PMID:22484959;PMID:23845516 -2.4.1.20 d-mannose thermotoga maritima 4.4 4.4 1 PMID:12596851 -2.4.1.20 d-xylose acetivibrio thermocellus 44.3 23.775 2 PMID:12153715;PMID:37833899 -2.4.1.20 d-xylose cellulomonas uda 8.7 8.7 1 * -2.4.1.20 d-xylose ruminococcus albus 16.5 16.5 1 PMID:22484959 -2.4.1.20 d-xylose thermosipho africanus 1.37 1.37 1 PMID:28687766 -2.4.1.20 d-xylose thermotoga maritima 40.0 40.0 1 PMID:12596851 -2.4.1.20 gentiobiose cellulomonas gilvus 7.2 7.2 1 PMID:16646954 -2.4.1.20 isomaltose cellulomonas gilvus 1.9 1.9 1 PMID:16646954 -2.4.1.20 lactose cellulomonas uda 0.109 0.109 1 PMID:19487233 -2.4.1.20 melibiose cellulomonas gilvus 2.3 2.3 1 PMID:16646954 -2.4.1.20 phosphate cellulomonas uda 15.4 15.4 2 * -2.4.1.203 cis-zeatin phaseolus lunatus 0.04 0.04 1 PMID:15728338 -2.4.1.203 m-topolin phaseolus lunatus 0.08 0.08 1 PMID:15728338 -2.4.1.203 trans-zeatin phaseolus lunatus 0.45 0.45 1 PMID:15728338 -2.4.1.207 [xyl(alpha1-6)]glc(beta1-4)[xyl(alpha1-6)]glc(beta1-4)[xyl(alpha1-6)]glc(beta1-4)glc(beta1-4)[xyl(alpha1-6)]glc(beta1-4)[xyl(alpha1-6)]glc(beta1-4)[xyl(alpha1-6)]glc(beta1-4)glc populus tremula x populus tremuloides 0.45 0.45 1 PMID:18511421 -2.4.1.207 [xylp(alpha1,6)]-glcp(beta1,4)-[galp(beta1,2)-xylp(alpha1,6)]-glcp(beta1,4)-[galp(beta1,2)-xylp(alpha1,6)]-glcp(beta1,4)-glcp hordeum vulgare 0.17 0.021 3 PMID:20117073 -2.4.1.207 [xylp(alpha1,6)]-glcp(beta1,4)-[xylp(alpha1,6)]-glcp(beta1,4)-[galp(beta1,2)-xylp(alpha1,6)]-glcp(beta1,4)-glcp hordeum vulgare 0.12 0.017 3 PMID:20117073 -2.4.1.207 [xylp(alpha1,6)]-glcp(beta1,4)-[xylp(alpha1,6)]-glcp(beta1,4)-[xylp(alpha1,6)]-glcp(beta1,4)-glcp hordeum vulgare 0.058 0.006 3 PMID:20117073 -2.4.1.207 alpha-d-xyl-(1->6)-[alpha-d-xyl-(1->6)-[alpha-d-xyl-(1->6)-beta-d-glc-(1->4)]-beta-d-glc-(1->4)]-beta-d-glc-(1->4)-d-glc pinus radiata 1.02 1.02 1 PMID:30684844 -2.4.1.207 gal(beta1-4)glc(beta1-4)[xyl(alpha1-6)]glc(beta1-4)[xyl(alpha1-6)]glc(beta1-4)[xyl(alpha1-6)]glc(beta1-4)glc(beta1-4)[xyl(alpha1-6)]glc(beta1-4)[xyl(alpha1-6)]glc(beta1-4)[xyl(alpha1-6)]glc(beta1-4)glc populus tremula x populus tremuloides 4.8 4.8 1 PMID:18511421 -2.4.1.207 glc8-based xyloglucan oligosaccharide hordeum vulgare 0.139 0.139 1 PMID:19076217 -2.4.1.207 pea xyloglucan arabidopsis thaliana 0.00031 0.00031 1 PMID:9306698 -2.4.1.207 reduced xyloglucan-derived heptasaccharide hordeum vulgare 0.0089 0.00565 2 PMID:19076217 -2.4.1.207 tamarind xyloglucan arabidopsis thaliana 0.00018 0.00018 1 PMID:9306698 -2.4.1.207 xyloglucan fragaria chiloensis 8.21 8.21 1 PMID:32403246 -2.4.1.207 xyloglucan oligosaccharide arabidopsis thaliana 0.00043 0.00023 3 PMID:33825243 -2.4.1.207 xyloglucan oligosaccharide brachypodium distachyon 0.0151 0.00995 2 PMID:33825243 -2.4.1.207 xyloglucan oligosaccharide populus trichocarpa 0.0483 0.00678 3 PMID:33825243 -2.4.1.207 xyloglucan oligosaccharide triticum aestivum 0.0003167 0.00019835 2 PMID:33825243 -2.4.1.207 xyloglucan oligosaccharide xxxg populus tomentosa 0.1795 0.15675 2 PMID:31730960 -2.4.1.21 adp-glucose phaseolus vulgaris 333.0 284.0 2 PMID:17681016 -2.4.1.21 amylopectin phaseolus vulgaris 235.0 235.0 1 PMID:17681016 -2.4.1.21 glycogen phaseolus vulgaris 412.0 412.0 1 PMID:17681016 -2.4.1.210 limonin citrus maxima x citrus paradisi 91.7 91.7 1 * -2.4.1.211 alpha-d-galactose 1-phosphate bifidobacterium longum 10.7 10.7 1 PMID:19124470 -2.4.1.211 beta-d-galactopyranosyl-1,3-n-acetyl-d-galactosamine cutibacterium acnes 103.0 103.0 1 PMID:19132369 -2.4.1.211 beta-d-galactopyranosyl-1,3-n-acetyl-d-galactosamine vibrio vulnificus 2.2 2.2 1 PMID:18723650 -2.4.1.211 beta-d-galactopyranosyl-1,3-n-acetyl-d-glucosamine cutibacterium acnes 14.0 14.0 1 PMID:19132369 -2.4.1.211 beta-d-galactopyranosyl-1,3-n-acetyl-d-glucosamine vibrio vulnificus 45.0 45.0 1 PMID:18723650 -2.4.1.211 galacto-n-biose bifidobacterium longum 65.0 65.0 1 * -2.4.1.211 galacto-n-biose lachnoclostridium phytofermentans 50.0 44.5 2 PMID:19491100 -2.4.1.211 lacto-n-biose i bifidobacterium longum 27.0 27.0 1 * -2.4.1.211 lacto-n-biose i lachnoclostridium phytofermentans 40.0 39.5 2 PMID:19491100 -2.4.1.211 n-acetyl-d-galactosamine cutibacterium acnes 42.0 42.0 1 PMID:19132369 -2.4.1.211 n-acetyl-d-galactosamine lachnoclostridium phytofermentans 48.0 41.0 2 PMID:19491100 -2.4.1.211 n-acetyl-d-glucosamine cutibacterium acnes 5.9 5.9 1 PMID:19132369 -2.4.1.211 n-acetyl-d-glucosamine lachnoclostridium phytofermentans 49.0 45.5 2 PMID:19491100 -2.4.1.212 hyaluronan oligomer ha4 pasteurella multocida 7.9 7.9 1 * -2.4.1.212 hyaluronan oligomer ha5 pasteurella multocida 7.9 7.9 1 * -2.4.1.212 hyaluronan oligomer ha6 pasteurella multocida 13.5 13.5 1 * -2.4.1.212 hyaluronan oligomer ha8 pasteurella multocida 8.8 8.8 1 * -2.4.1.212 udp-d-glucosamine candidatus mycoplasma liparidae 2.1 2.1 1 PMID:40297469 -2.4.1.212 udp-d-glucuronate candidatus mycoplasma liparidae 6.54 6.54 1 PMID:40297469 -2.4.1.212 udp-d-glucuronate streptococcus dysgalactiae subsp. equisimilis 120.0 120.0 1 PMID:15248781 -2.4.1.215 cis-zeatin oryza sativa japonica group 0.9 0.53 3 PMID:22811434 -2.4.1.215 cis-zeatin zea mays 0.01 0.01 1 PMID:15728338 -2.4.1.215 o-topolin zea mays 0.03 0.03 1 PMID:15728338 -2.4.1.216 alpha,alpha-trehalose 6-phosphate badhamia polycephala 7.72 7.72 1 PMID:37832387 -2.4.1.216 glucose 6-phosphate lactococcus lactis ssp. lactis 759.0 759.0 1 PMID:28537141 -2.4.1.217 3-phospho-d-glycerate dehalococcoides mccartyi 3.9 3.9 1 PMID:15205409 -2.4.1.217 gdp-mannose dehalococcoides mccartyi 3.9 3.9 1 PMID:15205409 -2.4.1.218 hydroquinone rauvolfia serpentina 0.00038 0.00038 1 PMID:28583673 -2.4.1.218 vanillin rauvolfia serpentina 2.59 2.59 1 PMID:12542702 -2.4.1.220 udp-glucose persicaria tinctoria 12.0 10.55 2 PMID:29309053 -2.4.1.221 gdp-fucose homo sapiens 2.4 2.4 1 PMID:22588082 -2.4.1.221 tsr4 homo sapiens 2.4 2.4 1 PMID:22588082 -2.4.1.222 udp-beta-d-glcnac mus musculus 0.08 0.08 1 PMID:19028689 -2.4.1.227 biotinylated citronellyl-lipid i escherichia coli 0.317 0.267 3 * -2.4.1.227 murnac(nepsilon-dansylpentapeptide)-pyrophosphoryl (r,s)-alpha-dihydroheptaprenol escherichia coli 0.933 0.933 1 PMID:1649817 -2.4.1.227 synthetic substrate analogue 2 escherichia coli 2.23 2.23 1 PMID:12022887 -2.4.1.227 synthetic substrate analogue 7 escherichia coli 14.0 14.0 2 PMID:12022887;PMID:12538870 -2.4.1.227 udp-glcnac escherichia coli 0.72 0.72 1 PMID:17692452 -2.4.1.227 udp-n-acetylglucosamine escherichia coli 0.93 0.6000000000000001 2 PMID:18081839 -2.4.1.230 2-alpha-d-glucosyl-d-glucose escherichia coli 1.1 1.1 1 PMID:29684280 -2.4.1.230 2-alpha-d-glucosyl-d-glucose pyrococcus sp. 37.7 37.7 1 PMID:24391053 -2.4.1.230 d-glucose escherichia coli 2.4 2.4 1 PMID:37475702 -2.4.1.230 phosphate pyrococcus sp. 37.7 37.7 1 PMID:24391053 -2.4.1.230 sucrose escherichia coli 5.3 5.3 1 PMID:37475702 -2.4.1.231 2-dehydro-d-glucose pleurotus ostreatus 4.5 4.5 1 PMID:17222933 -2.4.1.231 2-deoxy-d-glucose pleurotus ostreatus 0.27 0.27 1 PMID:17222933 -2.4.1.231 2-fluoro-d-glucose pleurotus ostreatus 0.89 0.89 1 PMID:17222933 -2.4.1.231 alpha,alpha-trehalose lactobacillus acidophilus 2.7 1.5150000000000001 2 PMID:20713411 -2.4.1.231 alpha,alpha-trehalose pleurotus ostreatus 18.3 18.3 1 PMID:17222933 -2.4.1.231 alpha,alpha-trehalose schizophyllum commune 16.4 14.1 5 PMID:10393097;PMID:11389683;PMID:11736665;PMID:16640506 -2.4.1.231 alpha-d-glucose pleurotus ostreatus 16.8 16.8 1 PMID:17222933 -2.4.1.231 alpha-d-glucose schizophyllum commune 14.1 10.15 4 PMID:10393097;PMID:11736665;PMID:16640506 -2.4.1.231 alpha-d-glucose 1-fluoride schizophyllum commune 0.11 0.11 1 PMID:11931662 -2.4.1.231 alpha-d-glucose 1-phosphate pleurotus ostreatus 16.0 16.0 1 PMID:17222933 -2.4.1.231 alpha-d-glucose 1-phosphate schizophyllum commune 14.1 9.75 4 PMID:10393097;PMID:11389683;PMID:16640506 -2.4.1.231 arsenate pleurotus ostreatus 1.15 1.15 1 PMID:17222933 -2.4.1.231 d-mannose pleurotus ostreatus 0.42 0.42 1 PMID:17222933 -2.4.1.231 phosphate pleurotus ostreatus 17.6 17.6 1 PMID:17222933 -2.4.1.231 phosphate schizophyllum commune 16.4 14.0 3 PMID:10393097;PMID:16640506 -2.4.1.234 isorhamnetin prunus persica 0.00105 0.00105 1 PMID:35357710 -2.4.1.234 kaempferol eriobotrya japonica 3.3689 3.3689 1 PMID:39805168 -2.4.1.234 kaempferol petunia x hybrida 61.1 61.1 1 PMID:10567367 -2.4.1.234 kaempferol prunus persica 0.00097 0.00097 1 PMID:35357710 -2.4.1.234 kaempferol 3-o-beta-d-galactoside petunia x hybrida 59.9 59.9 1 PMID:10567367 -2.4.1.234 quercetin eriobotrya japonica 3.9671 3.9671 1 PMID:39805168 -2.4.1.234 quercetin petunia x hybrida 59.8 59.8 1 PMID:10567367 -2.4.1.234 quercetin prunus persica 0.0009 0.0009 1 PMID:35357710 -2.4.1.234 quercetin 3-o-galactoside petunia x hybrida 82.3 82.3 1 PMID:10567367 -2.4.1.234 udp petunia x hybrida 89.6 70.25 2 PMID:10567367 -2.4.1.234 udp-galactose petunia x hybrida 61.2 59.3 2 PMID:10567367 -2.4.1.236 udp-beta-l-rhamnose dipsacus asperoides 2e-06 2e-06 1 PMID:39515003 -2.4.1.245 adp pyrococcus horikoshii 1.7 1.7 1 * -2.4.1.245 adp thermotoga maritima 11.1 11.1 1 * -2.4.1.245 adp-alpha-d-glucose pyrococcus horikoshii 0.44 0.44 1 * -2.4.1.245 adp-alpha-d-glucose thermotoga maritima 20.0 20.0 1 * -2.4.1.245 alpha,alpha-trehalose pyrococcus horikoshii 1.2 1.2 1 * -2.4.1.245 gdp pyrococcus horikoshii 1.7 1.7 1 * -2.4.1.245 gdp thermotoga maritima 9.7 9.7 1 * -2.4.1.245 gdp-alpha-d-glucose pyrococcus horikoshii 0.54 0.54 1 * -2.4.1.245 gdp-alpha-d-glucose thermotoga maritima 34.0 34.0 1 * -2.4.1.245 udp pyrococcus horikoshii 1.5 1.5 1 * -2.4.1.245 udp thermotoga maritima 7.1 7.1 1 * -2.4.1.245 udp-alpha-d-glucose pyrococcus horikoshii 0.53 0.53 1 * -2.4.1.245 udp-alpha-d-glucose thermotoga maritima 25.0 25.0 1 * -2.4.1.247 2-deoxy-d-glucose lachnoclostridium phytofermentans 8.0 8.0 1 PMID:19491100 -2.4.1.247 2-deoxy-d-glucose opitutus terrae 3.7 3.7 1 * -2.4.1.247 beta-d-galactosyl-(1->4)-l-rhamnose opitutus terrae 60.0 60.0 1 * -2.4.1.247 d-galactose lachnoclostridium phytofermentans 24.0 24.0 1 PMID:19491100 -2.4.1.247 d-galactose opitutus terrae 37.0 37.0 1 * -2.4.1.247 d-galactosyl-beta-1,4-l-rhamnose lachnoclostridium phytofermentans 45.0 45.0 1 PMID:19491100 -2.4.1.247 d-glucose lachnoclostridium phytofermentans 85.0 85.0 1 PMID:19491100 -2.4.1.247 d-glucose opitutus terrae 33.0 33.0 1 * -2.4.1.247 d-xylose opitutus terrae 19.0 19.0 1 * -2.4.1.247 l-lyxose lachnoclostridium phytofermentans 120.0 120.0 1 PMID:19491100 -2.4.1.247 l-lyxose opitutus terrae 14.0 14.0 1 * -2.4.1.247 l-mannose lachnoclostridium phytofermentans 170.0 170.0 1 PMID:19491100 -2.4.1.247 l-mannose opitutus terrae 75.0 75.0 1 * -2.4.1.247 l-rhamnose lachnoclostridium phytofermentans 74.0 74.0 1 PMID:19491100 -2.4.1.247 l-rhamnose opitutus terrae 50.0 50.0 1 * -2.4.1.249 delphinidin 3-o-(6''-o-malonyl)-beta-d-glucoside clitoria ternatea 4.4 4.4 1 PMID:17668234 -2.4.1.249 delphinidin 3-o-(6''-o-malonyl)-beta-d-glucoside-3'-o-beta-glucoside clitoria ternatea 5.4 5.4 1 PMID:17668234 -2.4.1.249 udp-d-glucose clitoria ternatea 5.1 5.0 2 PMID:17668234 -2.4.1.25 maltoheptaose aquifex aeolicus 16.0 16.0 1 * -2.4.1.25 maltoheptaose pyrobaculum aerophilum 8.7 8.7 1 PMID:16151092 -2.4.1.25 maltoheptaose thermus thermophilus 213.0 213.0 1 PMID:17407266 -2.4.1.25 maltohexaose aquifex aeolicus 22.0 22.0 1 * -2.4.1.25 maltohexaose pyrobaculum aerophilum 8.9 8.9 1 PMID:16151092 -2.4.1.25 maltohexaose thermus thermophilus 304.0 304.0 1 PMID:17407266 -2.4.1.25 maltopentaose aquifex aeolicus 22.0 22.0 1 * -2.4.1.25 maltopentaose corynebacterium glutamicum 4.8 4.8 1 PMID:27507216 -2.4.1.25 maltopentaose pyrobaculum aerophilum 24.8 24.8 1 PMID:16151092 -2.4.1.25 maltopentaose thermus thermophilus 329.0 329.0 1 PMID:17407266 -2.4.1.25 maltose aquifex aeolicus 1.3 1.3 1 * -2.4.1.25 maltosyl-beta-cyclodextrin saccharolobus solfataricus 0.0113 0.0113 1 PMID:18060856 -2.4.1.25 maltotetraose aquifex aeolicus 17.0 17.0 1 * -2.4.1.25 maltotetraose pyrobaculum aerophilum 51.2 51.2 1 PMID:16151092 -2.4.1.25 maltotetraose thermus thermophilus 425.0 425.0 1 PMID:17407266 -2.4.1.25 maltotriose aquifex aeolicus 18.0 18.0 1 * -2.4.1.25 maltotriose arabidopsis thaliana 580.0 580.0 1 * -2.4.1.25 maltotriose corynebacterium glutamicum 3033.0 1405.2 4 PMID:22865069;PMID:27507216;PMID:28522291;PMID:29885290 -2.4.1.25 maltotriose manihot esculenta 894.0 894.0 1 * -2.4.1.25 maltotriose pyrobaculum aerophilum 115.0 115.0 1 PMID:16151092 -2.4.1.25 maltotriose thermus brockianus 0.015 0.015 1 PMID:21117235 -2.4.1.25 maltotriose thermus thermophilus 317.0 317.0 1 PMID:17407266 -2.4.1.25 starch corynebacterium glutamicum 103.0 0.0073 3 PMID:36698977 -2.4.1.254 udp-d-glucuronate bellis perennis 35.0 34.5 2 PMID:15509561 -2.4.1.255 udp-glcnac homo sapiens 1.76 0.00075 6 PMID:19957065;PMID:22311971;PMID:26240142 -2.4.1.255 udp-glcnac streptococcus pneumoniae tigr4 1.25 0.6859999999999999 2 PMID:24936067 -2.4.1.255 udp-n-azidoacetylglucosamine homo sapiens 0.0015 0.0015 1 PMID:26240142 -2.4.1.255 ysdspstst homo sapiens 2.48 2.48 1 PMID:19957065 -2.4.1.264 udp-glucuronate xanthomonas campestris 0.087 0.087 1 PMID:18596046 -2.4.1.266 udp-glucose mycobacterium tuberculosis 0.82 0.82 1 PMID:25317963 -2.4.1.269 d-glycerate rhodothermus marinus 6.5 1.02 5 PMID:15951819;PMID:21288903 -2.4.1.269 d-lactate rhodothermus marinus 0.017 0.0098 2 PMID:15951819;PMID:21288903 -2.4.1.269 gdp-glucose rhodothermus marinus 1.1 0.865 2 PMID:15951819 -2.4.1.269 gdp-mannose rhodothermus marinus 6.1 1.02 3 PMID:15951819;PMID:21288903 -2.4.1.269 glycolic acid rhodothermus marinus 0.0052 0.0052 1 PMID:15951819 -2.4.1.27 5-hydroxymethyl cytosine containing phage t4 dna tequatrovirus t4 1.283 1.283 1 PMID:22229759 -2.4.1.27 dna containing 12 5-hydroxymethyl cytosine residues tequatrovirus t4 1.033 1.033 1 PMID:22229759 -2.4.1.27 dna containing 2 5-hydroxymethyl cytosine residues tequatrovirus t4 2.8 2.8 1 PMID:22229759 -2.4.1.27 dna containing 24 5-hydroxymethyl cytosine residues tequatrovirus t4 9.66 9.66 1 PMID:22229759 -2.4.1.27 dna containing 6 5-hydroxymethyl cytosine residues tequatrovirus t4 1.666 1.666 1 PMID:22229759 -2.4.1.272 glycyrrhetinic acid-3-o-monoglucoside glycine max 0.047 0.047 1 PMID:32689796 -2.4.1.272 glycyrrhetinic acid-3-o-monoglucuronide glycine max 2.07 2.07 1 PMID:32689796 -2.4.1.277 10-deoxymethynolide streptomyces venezuelae 1.0 0.5046 2 PMID:20695498 -2.4.1.277 tdp-3-dimethylamino-4,6-dideoxy-alpha-d-glucopyranose streptomyces venezuelae 1.33 0.6681 2 PMID:20695498 -2.4.1.278 3-alpha-mycarosylerythronolide b saccharopolyspora erythraea 1.7 0.8584999999999999 2 PMID:15303858;PMID:16218575 -2.4.1.278 dtdp-3-dimethylamino-4,6-dideoxy-alpha-d-glucopyranose saccharopolyspora erythraea 1.7 1.7 1 PMID:15303858 -2.4.1.279 1,5-anhydro-d-glucitol lachnoclostridium phytofermentans 120.0 75.0 2 PMID:21808968 -2.4.1.279 3-o-alpha-d-glucopyranosyl-d-glucopyranose lachnoclostridium phytofermentans 31.0 31.0 1 * -2.4.1.279 beta-d-glucopyranose 1-phosphate lachnoclostridium phytofermentans 58.0 58.0 1 * -2.4.1.279 d-galactose lachnoclostridium phytofermentans 69.0 47.0 2 PMID:21808968 -2.4.1.279 d-glucose lachnoclostridium phytofermentans 110.0 81.0 2 PMID:21808968 -2.4.1.279 d-xylose lachnoclostridium phytofermentans 118.0 79.0 2 PMID:21808968 -2.4.1.279 methyl alpha-d-glucopyranoside lachnoclostridium phytofermentans 8.3 8.3 1 * -2.4.1.279 phosphate lachnoclostridium phytofermentans 67.0 67.0 1 PMID:21808968 -2.4.1.281 1,5-anhydro-d-glucitol ruminococcus albus 20.7 20.7 1 PMID:23093406 -2.4.1.281 2-deoxy-2-fluoro-d-glucose ruminococcus albus 5.71 5.71 1 PMID:23093406 -2.4.1.281 2-deoxy-d-glucose ruminococcus albus 11.7 11.7 1 PMID:23093406 -2.4.1.281 3-deoxy-3-fluoro-d-glucose ruminococcus albus 0.94 0.94 1 PMID:23093406 -2.4.1.281 3-o-methyl-d-glucose ruminococcus albus 0.763 0.763 1 PMID:23093406 -2.4.1.281 4-o-beta-d-mannopyranosyl-d-glucopyranose bacteroides fragilis 42.2 42.2 1 PMID:21539815 -2.4.1.281 4-o-beta-d-mannopyranosyl-d-glucopyranose ruminococcus albus 83.3 50.4 2 PMID:23093406 -2.4.1.281 6-deoxy-6-fluoro-d-glucose ruminococcus albus 42.0 42.0 1 PMID:23093406 -2.4.1.281 6-deoxy-d-glucose ruminococcus albus 177.0 177.0 1 PMID:23093406 -2.4.1.281 alpha-d-mannose 1-phosphate ruminococcus albus 52.1 52.1 1 PMID:26913570 -2.4.1.281 cellobiose ruminococcus albus 20.2 20.2 1 PMID:23093406 -2.4.1.281 d-allose ruminococcus albus 0.667 0.667 1 PMID:23093406 -2.4.1.281 d-glucose ruminococcus albus 126.0 45.1 4 PMID:23093406;PMID:26913570 -2.4.1.281 d-mannose ruminococcus albus 5.12 5.12 1 PMID:23093406 -2.4.1.281 gentiobiose ruminococcus albus 26.1 26.1 1 PMID:23093406 -2.4.1.281 laminaribiose ruminococcus albus 11.6 11.6 1 PMID:23093406 -2.4.1.281 maltose ruminococcus albus 5.07 5.07 1 PMID:23093406 -2.4.1.281 methyl alpha-d-glucoside ruminococcus albus 20.7 20.7 1 PMID:23093406 -2.4.1.281 methyl beta-d-glucoside ruminococcus albus 35.2 35.2 1 PMID:23093406 -2.4.1.281 n,n'-diacetylchitobiose ruminococcus albus 6.34 6.34 1 PMID:23093406 -2.4.1.281 n-acetyl-d-glucosamine ruminococcus albus 15.8 15.8 1 PMID:23093406 -2.4.1.281 phosphate bacteroides fragilis 24.8 24.8 1 PMID:21539815 -2.4.1.281 sophorose ruminococcus albus 13.8 13.8 1 PMID:23093406 -2.4.1.282 beta-d-glucose 1-phosphate lachnoclostridium phytofermentans 2.5 2.5 1 PMID:22277537 -2.4.1.282 l-rhamnose lachnoclostridium phytofermentans 1.6 1.6 1 PMID:22277537 -2.4.1.284 udp-d-glucose streptomyces kanamyceticus 0.29 0.29 1 PMID:21983602 -2.4.1.284 udp-n-acetyl-alpha-d-glucosamine streptomyces kanamyceticus 0.33 0.33 1 PMID:21983602 -2.4.1.288 beta-d-galf-(1->5)-beta-d-galf-(1->6)-beta-d-galf-o(ch2)7ch3 mycobacterium tuberculosis 7.2 7.2 1 PMID:22707726 -2.4.1.288 d-galactofuranosyl-(1->5)-beta-d-galactofuranosyl-(1->5)-beta-d-galactofuranose mycobacterium tuberculosis 0.87 0.87 1 PMID:27302377 -2.4.1.288 d-galactofuranosyl-(1->5)-beta-d-galactofuranosyl-(1->6)-beta-d-galactofuranose mycobacterium tuberculosis 0.72 0.72 1 PMID:27302377 -2.4.1.288 d-galactofuranosyl-(1->6)-beta-d-galactofuranose mycobacterium tuberculosis 1.0 1.0 1 PMID:27302377 -2.4.1.288 d-galactofuranosyl-(1->6)-beta-d-galactofuranosyl-(1->5)-beta-d-galactofuranose mycobacterium tuberculosis 3.7 3.7 1 PMID:27302377 -2.4.1.288 d-galactofuranosyl-(1->6)-beta-d-galactofuranosyl-(1->5)-beta-d-galactofuranosyl-(1->6)-beta-d-galactofuranose mycobacterium tuberculosis 2.9 2.9 1 PMID:27302377 -2.4.1.288 d-galactofuranosyl-(1->6)-beta-d-galactofuranosyl-(1->6)-beta-d-galactofuranose mycobacterium tuberculosis 5.3 5.3 1 PMID:27302377 -2.4.1.288 dtdp-alpha-d-galactofuranose mycobacterium tuberculosis 1.62 1.62 1 PMID:22499274 -2.4.1.288 gdp-alpha-d-glucopyranose leishmania major 0.4 0.4 1 PMID:30514885 -2.4.1.288 gdp-alpha-d-mannopyranose leishmania major 1.43 1.43 1 PMID:30514885 -2.4.1.288 udp-3-deoxy-alpha-d-threo-hexofuranose mycobacterium tuberculosis 0.02 0.02 1 PMID:22499274 -2.4.1.288 udp-5-deoxy-alpha-d-galactofuranose mycobacterium tuberculosis 0.17 0.17 1 PMID:22499274 -2.4.1.288 udp-6-deoxy-alpha-d-galactofuranose mycobacterium tuberculosis 1.32 1.32 1 PMID:22499274 -2.4.1.288 udp-alpha-d-arabinofuranose mycobacterium tuberculosis 0.25 0.25 1 PMID:22499274 -2.4.1.288 udp-alpha-d-galactofuranose leishmania major 512.0 88.3 3 PMID:30514885 -2.4.1.288 udp-alpha-d-galactofuranose mycobacterium tuberculosis 7.2 4.69 4 PMID:18423586;PMID:22499274;PMID:22707726 -2.4.1.288 udp-alpha-d-galactopyranose leishmania major 7.8 5.33 3 PMID:30514885 -2.4.1.288 udp-alpha-d-glucopyranose leishmania major 3.4 3.4 1 PMID:30514885 -2.4.1.291 udp-n-acetyl-d-galactosaminuronic acid campylobacter concisus 71.7 70.85 2 PMID:38110367 -2.4.1.292 (galnac-alpha1,4)4-galnac-alpha1,3-bac-alpha1-pp-undecaprenyl campylobacter jejuni 2.0 2.0 1 PMID:29386647 -2.4.1.294 cyanidin apium graveolens 6.16 6.16 2 PMID:29520459 -2.4.1.294 cyanidin camellia sinensis var. sinensis 0.31 0.31 1 PMID:34217130 -2.4.1.294 delphinidin camellia sinensis var. sinensis 0.624 0.624 1 PMID:34217130 -2.4.1.294 myricetin camellia sinensis var. sinensis 0.504 0.504 1 PMID:34217130 -2.4.1.298 malvidin 3-o-beta-d-glucoside vitis amurensis 0.279 0.279 1 PMID:26159788 -2.4.1.299 1-o-vanilloyl-beta-d-glucose dianthus caryophyllus 0.01 0.01 1 PMID:20971893 -2.4.1.299 cyanidin 3-o-beta-d-glucoside dianthus caryophyllus 0.07 0.065 2 PMID:20971893 -2.4.1.30 alpha-d-galactose 1-phosphate homo sapiens 0.77 0.615 2 PMID:31657512 -2.4.1.30 alpha-d-glucosamine 1-phosphate homo sapiens 0.09 0.065 2 PMID:31657512 -2.4.1.30 alpha-d-glucose 1-phosphate homo sapiens 10.6 9.95 2 PMID:31657512 -2.4.1.30 alpha-d-mannose 1-phosphate homo sapiens 0.15 0.09 2 PMID:31657512 -2.4.1.30 d-glucose anaerolinea thermophila 784.0 784.0 1 PMID:38659290 -2.4.1.30 d-glucose euglena gracilis 1.1 1.1 1 PMID:33970317 -2.4.1.30 d-glucose euglena gracilis var. saccharophila 1.1 1.1 1 PMID:38659290 -2.4.1.30 laminaribiose euglena gracilis 1.1 1.1 1 PMID:33970317 -2.4.1.30 laminarihexaose euglena gracilis 1.1 1.1 1 PMID:33970317 -2.4.1.30 laminaripentaose euglena gracilis 1.1 1.1 1 PMID:33970317 -2.4.1.30 laminaritetraose euglena gracilis 1.1 1.1 1 PMID:33970317 -2.4.1.30 laminaritriose euglena gracilis 1.1 1.1 1 PMID:33970317 -2.4.1.300 1-o-vanilloyl-beta-d-glucose delphinium grandiflorum 0.1 0.1 1 PMID:20971893 -2.4.1.300 cyanidin 3-o-beta-d-glucoside delphinium grandiflorum 0.17 0.17 1 PMID:20971893 -2.4.1.301 udp-alpha-d-glucose streptomyces kanamyceticus 0.053 0.053 1 PMID:21983602 -2.4.1.301 udp-alpha-d-kanosamine streptomyces kanamyceticus 0.056 0.056 1 PMID:21983602 -2.4.1.302 cyclonovobiocic acid streptomyces niveus 118.0 118.0 1 PMID:12680772 -2.4.1.302 dtdp-beta-l-noviose streptomyces niveus 226.0 226.0 1 PMID:12680772 -2.4.1.302 n-(4,7-dihydroxy-8-methyl-2-oxo-2h-chromen-3-yl)-4-hydroxy-3-methylbenzamide streptomyces sp. 290.0 290.0 1 PMID:15218104 -2.4.1.302 novobiocic acid streptomyces niveus 313.0 313.0 1 PMID:12680772 -2.4.1.302 novobiocic acid streptomyces sp. 219.0 219.0 1 PMID:15218104 -2.4.1.31 2-deoxy-d-glucose acholeplasma laidlawii 1.0 1.0 2 PMID:22982171;PMID:33970317 -2.4.1.31 alpha-d-glucose 1-phosphate paenibacillus sp. ym-1 13.0 13.0 1 PMID:29856496 -2.4.1.31 alpha-d-glucose 1-phosphate paenibacillus sp. ym1 72.3 46.599999999999994 2 * -2.4.1.31 alpha-d-mannose 1-phosphate paenibacillus sp. ym-1 0.08 0.08 1 PMID:29856496 -2.4.1.31 d-glucose acholeplasma laidlawii 1.4 1.4 2 PMID:22982171;PMID:33970317 -2.4.1.31 d-glucose paenibacillus sp. ym-1 15.4 15.4 1 PMID:29856496 -2.4.1.31 d-glucose paenibacillus sp. ym1 72.3 21.8 3 PMID:33970317 -2.4.1.31 laminaribiose acholeplasma laidlawii 6.5 6.5 1 PMID:22982171 -2.4.1.31 laminaribiose paenibacillus sp. 19.0 19.0 1 PMID:22313784 -2.4.1.310 udp-alpha-d-glucose amycolatopsis orientalis 0.55 0.4165 2 PMID:11294642;PMID:11470430 -2.4.1.310 vancomycin aglycone amycolatopsis orientalis 0.283 0.283 1 PMID:11294642 -2.4.1.311 desvancosaminyl-vancomycin amycolatopsis orientalis 0.038 0.038 1 PMID:15070728 -2.4.1.311 dtdp-beta-l-4-epi-vancosamine amycolatopsis orientalis 0.038 0.038 1 PMID:15070728 -2.4.1.312 3-o-(alpha-d-mannosyl)-l-threonyl-[iqeppsrivp-t-ptspaiappt] homo sapiens 1.0 1.0 1 PMID:27932460 -2.4.1.312 3-o-(alpha-d-mannosyl)-l-threonyl-[pkrvrrqiha-t-ptpvtaigpp] homo sapiens 13.0 12.5 2 PMID:27932460 -2.4.1.312 3-o-(alpha-d-mannosyl)-l-threonyl-[tirtrgaiiq-t-lgpiqptr] homo sapiens 32.0 24.0 2 PMID:27932460 -2.4.1.312 3-o-(alpha-d-mannosyl)-l-threonyl-[yvep-t-av] homo sapiens 16.0 16.0 1 PMID:27932460 -2.4.1.315 1,2-diacyl-3-o-(alpha-d-glucopyranosyl)-sn-glycerol mycoplasmoides genitalium 0.023 0.023 1 PMID:21835921 -2.4.1.315 1,2-diacyl-sn-glycerol mycoplasmoides genitalium 1.13 1.13 1 PMID:21835921 -2.4.1.315 udp-alpha-d-galactose mycoplasmoides genitalium 1.1 0.5650000000000001 2 PMID:21835921 -2.4.1.315 udp-alpha-d-glucose mycoplasmoides genitalium 0.27 0.137 2 PMID:21835921 -2.4.1.319 4-o-beta-d-mannosyl-d-glucose ruminococcus albus 20.7 20.7 1 PMID:23093406 -2.4.1.319 [(1->4)-beta-d-mannosyl]2 ruminococcus albus 45.1 26.080000000000002 2 PMID:23093406 -2.4.1.319 [(1->4)-beta-d-mannosyl]3 ruminococcus albus 34.6 31.05 2 PMID:23093406 -2.4.1.319 [(1->4)-beta-d-mannosyl]4 ruminococcus albus 33.1 32.15 2 PMID:23093406 -2.4.1.319 [(1->4)-beta-d-mannosyl]5 ruminococcus albus 31.9 26.2 2 PMID:23093406 -2.4.1.319 [(1->4)-beta-d-mannosyl]6 ruminococcus albus 16.0 16.0 1 PMID:23093406 -2.4.1.319 beta-d-man-(1->4)-beta-d-man-(1->4)-beta-d-man-(1->4)-beta-d-man-(1->4)-beta-d-man-(1->4)-d-man ruminococcus albus 16.0 16.0 1 PMID:23093406 -2.4.1.319 beta-d-man-(1->4)-beta-d-man-(1->4)-beta-d-man-(1->4)-beta-d-man-(1->4)-d-man ruminococcus albus 31.9 26.2 2 PMID:23093406 -2.4.1.319 beta-d-man-(1->4)-beta-d-man-(1->4)-beta-d-man-(1->4)-d-man ruminococcus albus 33.1 32.15 2 PMID:23093406 -2.4.1.319 beta-d-man-(1->4)-beta-d-man-(1->4)-d-man ruminococcus albus 34.6 31.05 2 PMID:23093406 -2.4.1.319 beta-d-mannopyranosyl-(1->4)-d-mannopyranose ruminococcus albus 45.1 26.080000000000002 2 PMID:23093406 -2.4.1.320 4-o-beta-d-mannopyranosyl-n-acetyl-d-glucosamine bacteroides thetaiotaomicron 240.0 240.0 1 PMID:23943617 -2.4.1.320 4-o-beta-n-acetyl-d-glucosaminyl-n-acetyl-d-glucosamine bacteroides thetaiotaomicron 22.0 22.0 1 PMID:23943617 -2.4.1.320 alpha-d-mannose 1-phosphate bacteroides thetaiotaomicron 25.0 25.0 2 PMID:23943617 -2.4.1.320 n,n'-diacetylchitobiose bacteroides thetaiotaomicron 22.0 22.0 1 PMID:23943617 -2.4.1.320 n-acetyl-d-glucosamine bacteroides thetaiotaomicron 37.0 37.0 2 PMID:23943617 -2.4.1.320 phosphate bacteroides thetaiotaomicron 240.0 240.0 1 PMID:23943617 -2.4.1.321 4-o-beta-d-glucopyranosyl-d-gluconate neurospora crassa 306.0 306.0 1 PMID:24055472 -2.4.1.321 alpha-d-glucose 1-phosphate xanthomonas campestris 127.0 127.0 1 PMID:24055472 -2.4.1.321 alpha-d-glucose 1-phosphate xanthomonas campestris pv. campestris 127.0 127.0 1 PMID:24055472 -2.4.1.321 d-gluconate neurospora crassa 146.0 146.0 2 PMID:24055472 -2.4.1.321 d-gluconate saccharophagus degradans 130.0 130.0 1 PMID:26041776 -2.4.1.321 d-gluconate xanthomonas campestris 173.0 173.0 1 PMID:24055472 -2.4.1.321 d-gluconate xanthomonas campestris pv. campestris 173.0 173.0 1 PMID:24055472 -2.4.1.321 d-glucuronate saccharophagus degradans 34.6 34.6 1 PMID:26041776 -2.4.1.321 d-glucuronate xanthomonas campestris 43.0 43.0 1 PMID:24055472 -2.4.1.321 d-glucuronate xanthomonas campestris pv. campestris 43.0 43.0 1 PMID:24055472 -2.4.1.321 phosphate neurospora crassa 306.0 306.0 1 PMID:24055472 -2.4.1.322 desvancosaminyl-vancomycin amycolatopsis orientalis 1.12 1.12 1 PMID:15122882 -2.4.1.322 dtdp-beta-l-acosamine amycolatopsis orientalis 2.25 2.25 1 PMID:16045364 -2.4.1.322 dtdp-beta-l-daunosamine amycolatopsis orientalis 2.13 2.13 1 PMID:16045364 -2.4.1.322 udp-l-epi-vancosamine amycolatopsis orientalis 1.12 1.12 1 PMID:15122882 -2.4.1.323 7-deoxyloganetate catharanthus roseus 0.325 0.325 1 PMID:24104568 -2.4.1.323 udp-alpha-d-glucose catharanthus roseus 0.13 0.13 1 PMID:24104568 -2.4.1.324 7-deoxyloganetin catharanthus roseus 0.0355 0.0355 1 PMID:24104568 -2.4.1.324 7-deoxyloganetin gardenia jasminoides 0.13 0.13 1 PMID:21799001 -2.4.1.324 genipin gardenia jasminoides 1.04 1.04 1 PMID:21799001 -2.4.1.324 udp-alpha-d-glucose catharanthus roseus 0.032 0.032 1 PMID:24104568 -2.4.1.324 udp-alpha-d-glucose gardenia jasminoides 0.16 0.16 1 PMID:21799001 -2.4.1.326 aklavinone streptomyces galilaeus 0.004 0.0035 2 PMID:15911373 -2.4.1.326 dtdp-4-amino-2-deoxyrhamnose streptomyces galilaeus 0.003 0.003 1 PMID:15911373 -2.4.1.326 dtdp-beta-l-rhodosamine streptomyces galilaeus 0.16 0.08415 2 PMID:17685523 -2.4.1.326 dtdp-l-2-deoxyfucose streptomyces galilaeus 0.004 0.0025 2 PMID:15911373 -2.4.1.326 epsilon-rhodomycinone streptomyces galilaeus 0.001 0.001 1 PMID:15911373 -2.4.1.327 idarubicin streptomyces galilaeus 0.09 0.09 1 PMID:15078101 -2.4.1.327 rhodosaminyl aklavinone streptomyces galilaeus 1.09 0.5625 2 PMID:15078101 -2.4.1.329 alpha-d-glucopyranose 1-phosphate thermoanaerobacterium thermosaccharolyticum 14.4 14.4 2 PMID:24599311 -2.4.1.329 alpha-d-glucose 1-phosphate ilumatobacter coccineus 45.0 45.0 1 PMID:31405215 -2.4.1.329 beta-d-fructofuranose thermoanaerobacterium thermosaccharolyticum 16.9 16.9 1 PMID:24599311 -2.4.1.329 beta-d-fructofuranose 6-phosphate thermoanaerobacterium thermosaccharolyticum 24.2 24.2 2 PMID:24599311 -2.4.1.329 d-fructose 6-phosphate ilumatobacter coccineus 40.0 40.0 1 PMID:31405215 -2.4.1.329 phosphate ilumatobacter coccineus 110.0 110.0 1 PMID:31405215 -2.4.1.329 phosphate thermoanaerobacterium thermosaccharolyticum 59.3 59.3 2 PMID:24599311 -2.4.1.329 sucrose thermoanaerobacterium thermosaccharolyticum 66.2 66.2 1 PMID:24599311 -2.4.1.329 sucrose 6f-phosphate ilumatobacter coccineus 126.0 126.0 1 PMID:31405215 -2.4.1.329 sucrose 6f-phosphate mediterraneibacter gnavus 740.0 740.0 1 PMID:30913025 -2.4.1.329 sucrose 6f-phosphate thermoanaerobacterium thermosaccharolyticum 82.6 82.6 2 PMID:24599311 -2.4.1.330 beta-d-glucosyl crocetin gardenia jasminoides 0.036 0.036 2 PMID:22569263 -2.4.1.330 bis(beta-d-glucosyl) crocetin gardenia jasminoides 0.071 0.071 2 PMID:22569263 -2.4.1.332 2-o-alpha-d-glucopyranosyl-sn-glycerol salisediminibacterium selenitireducens 95.0 95.0 1 PMID:24466148 -2.4.1.332 beta-d-glucose 1-phosphate salisediminibacterium selenitireducens 180.0 180.0 1 PMID:24466148 -2.4.1.332 sn-glycerol salisediminibacterium selenitireducens 163.0 163.0 1 PMID:24466148 -2.4.1.333 2-o-beta-d-glucopyranosyl-2-o-beta-d-glucopyranosyl-2-o-beta-d-glucopyranosyl-2-o-beta-d-glucopyranosyl-d-glucopyranose lachnoclostridium phytofermentans 48.0 48.0 1 PMID:28198470 -2.4.1.333 2-o-beta-d-glucopyranosyl-2-o-beta-d-glucopyranosyl-2-o-beta-d-glucopyranosyl-2-o-beta-d-glucopyranosyl-d-glucopyranose listeria innocua 31.0 31.0 1 PMID:24647662 -2.4.1.333 2-o-beta-d-glucopyranosyl-2-o-beta-d-glucopyranosyl-2-o-beta-d-glucopyranosyl-d-glucopyranose lachnoclostridium phytofermentans 46.0 44.0 2 PMID:28198470 -2.4.1.333 2-o-beta-d-glucopyranosyl-2-o-beta-d-glucopyranosyl-2-o-beta-d-glucopyranosyl-d-glucopyranose listeria innocua 90.0 60.0 2 PMID:24647662 -2.4.1.333 2-o-beta-d-glucopyranosyl-2-o-beta-d-glucopyranosyl-d-glucopyranose lachnoclostridium phytofermentans 55.0 51.0 2 PMID:28198470 -2.4.1.333 2-o-beta-d-glucopyranosyl-2-o-beta-d-glucopyranosyl-d-glucopyranose listeria innocua 110.0 64.5 2 PMID:24647662 -2.4.1.333 2-o-beta-d-glucopyranosyl-d-glucopyranose lachnoclostridium phytofermentans 40.0 40.0 1 PMID:28198470 -2.4.1.333 alpha-d-glucose 1-phosphate lachnoclostridium phytofermentans 8.0 8.0 1 PMID:28198470 -2.4.1.333 alpha-d-glucose 1-phosphate listeria innocua 43.0 43.0 1 PMID:24647662 -2.4.1.333 phosphate lachnoclostridium phytofermentans 63.0 63.0 1 PMID:28198470 -2.4.1.333 sophorose listeria innocua 97.0 97.0 1 PMID:24647662 -2.4.1.334 3-o-alpha-d-glucopyranosyl-3-o-alpha-d-glucopyranosyl-3-o-alpha-d-glucopyranosyl-d-glucopyranose lachnoclostridium phytofermentans 8.5 8.5 1 * -2.4.1.334 3-o-alpha-d-glucopyranosyl-3-o-alpha-d-glucopyranosyl-d-glucopyranose lachnoclostridium phytofermentans 17.0 14.0 2 * -2.4.1.334 3-o-alpha-d-glucopyranosyl-d-glucopyranose lachnoclostridium phytofermentans 8.7 8.7 1 * -2.4.1.334 beta-d-glucopyranose 1-phosphate lachnoclostridium phytofermentans 5.1 5.1 1 * -2.4.1.334 kojibiose lachnoclostridium phytofermentans 3.5 3.5 1 * -2.4.1.334 maltose lachnoclostridium phytofermentans 2.7 2.7 1 * -2.4.1.339 alpha-d-mannose 1-phosphate listeria innocua 33.0 33.0 1 PMID:26632508 -2.4.1.339 beta-d-mannopyranosyl-(1->2)-beta-d-mannopyranosyl-(1->2)-d-mannopyranose listeria innocua 12.0 12.0 1 PMID:26632508 -2.4.1.339 beta-d-mannopyranosyl-(1->2)-d-mannopyranose listeria innocua 35.0 23.5 2 PMID:26632508 -2.4.1.339 d-fructose listeria innocua 3.9 3.9 1 PMID:26632508 -2.4.1.339 d-mannopyranose listeria innocua 31.0 31.0 1 PMID:26632508 -2.4.1.34 udpglucose staphylococcus aureus 0.717 0.29665 4 PMID:11470430 -2.4.1.340 [(1->2)-beta-d-mannosyl]2 thermoanaerobacter sp. 25.0 13.45 2 PMID:25500577 -2.4.1.340 [(1->2)-beta-d-mannosyl]3 thermoanaerobacter sp. 43.0 31.5 2 PMID:25500577 -2.4.1.340 [(1->2)-beta-d-mannosyl]4 thermoanaerobacter sp. 49.0 49.0 1 PMID:25500577 -2.4.1.340 alpha-d-mannose thermoanaerobacter sp. 1.9 1.9 1 PMID:25500577 -2.4.1.340 alpha-d-mannose 1-phosphate thermoanaerobacter sp. 22.0 22.0 1 PMID:25500577 -2.4.1.340 d-fructose thermoanaerobacter sp. 2.0 2.0 1 PMID:25500577 -2.4.1.341 beta-d-galactopyranosyl-(1->3)-n-acetyl-d-glucosamine escherichia coli 0.087 0.087 1 PMID:26703456 -2.4.1.341 gdp-beta-l-colitose escherichia coli 0.147 0.147 1 PMID:26703456 -2.4.1.341 gdp-l-fucose escherichia coli 0.2 0.2 1 PMID:26703456 -2.4.1.342 adp-alpha-d-glucose mycobacterium tuberculosis 29.2 19.9 4 PMID:27513637 -2.4.1.342 alpha-d-glucose-1-phosphate mycobacterium tuberculosis 97.9 80.6 3 PMID:27513637 -2.4.1.344 beta-d-gal-(1->3)-beta-d-glcnac-2-anthranilic acid aglycone thermosynechococcus vestitus 0.333 0.333 1 PMID:26864394 -2.4.1.344 gdp-beta-l-fucose thermosynechococcus vestitus 0.483 0.244 2 PMID:26864394 -2.4.1.350 mogrol siraitia grosvenorii 0.000411 0.00025550000000000003 2 PMID:25759326 -2.4.1.350 naringenin siraitia grosvenorii 0.45 0.45 1 PMID:25759326 -2.4.1.350 quercetin siraitia grosvenorii 0.41 0.41 1 PMID:25759326 -2.4.1.350 udp-alpha-d-glucose siraitia grosvenorii 0.00015 0.00015 1 * -2.4.1.352 2-o-(alpha-d-glucopyranosyl)-d-glycerate allomeiothermus silvanus 0.83 0.83 1 PMID:28754708 -2.4.1.352 2-o-(alpha-d-glucopyranosyl)-d-glycerate escherichia coli 2.1 2.1 1 PMID:29684280 -2.4.1.352 alpha-d-glucopyranose 1-phosphate allomeiothermus silvanus 96.0 96.0 1 PMID:28754708 -2.4.1.352 alpha-d-glucopyranose 1-phosphate winmispira thermophila 565.7 565.7 1 PMID:38508282 -2.4.1.352 d-glycerate allomeiothermus silvanus 128.0 128.0 1 PMID:28754708 -2.4.1.352 d-glycerate winmispira thermophila 505.3 505.3 1 PMID:38508282 -2.4.1.352 d-glycerate xylanimonas protaetiae 48.0 48.0 1 PMID:38175244 -2.4.1.352 fructose xylanimonas protaetiae 77.0 77.0 1 PMID:38175244 -2.4.1.352 l-glycerate xylanimonas protaetiae 42.0 42.0 1 PMID:38175244 -2.4.1.352 phosphate allomeiothermus silvanus 0.98 0.98 1 PMID:28754708 -2.4.1.352 phosphate escherichia coli 2.4 2.4 1 PMID:29684280 -2.4.1.352 sucrose xylanimonas protaetiae 70.0 70.0 1 PMID:38175244 -2.4.1.355 polyribitol phosphate staphylococcus aureus 1.1 0.8500000000000001 2 PMID:27973583 -2.4.1.355 udp-n-acetyl-d-glucosamine staphylococcus aureus 0.062 0.057499999999999996 2 PMID:27973583 -2.4.1.357 adp-alpha-d-glucose malus domestica 58.67 36.620000000000005 2 PMID:27731384 -2.4.1.357 isoliquiritigenin malus domestica 4.35 4.35 1 PMID:27731384 -2.4.1.357 kaempferol malus domestica 5.65 5.65 1 PMID:27731384 -2.4.1.357 luteolin malus domestica 3.24 3.24 1 PMID:27731384 -2.4.1.357 phloretin malus domestica 41.83 2.95 5 PMID:18573104;PMID:27316677;PMID:27731384;PMID:30399496 -2.4.1.357 quercetin malus domestica 7.41 6.795 2 PMID:27731384 -2.4.1.357 udp-alpha-d-galactose malus domestica 26.19 26.19 1 PMID:27731384 -2.4.1.357 udp-alpha-d-glucose malus domestica 42.59 25.88 6 PMID:27316677;PMID:27731384;PMID:30399496 -2.4.1.359 2-o-(alpha-d-glucopyranosyl)glycerol marinobacter adhaerens 14.0 14.0 2 PMID:29470619 -2.4.1.359 alpha-d-glucose 1-phosphate marinobacter adhaerens 6.0 6.0 2 PMID:29470619 -2.4.1.359 glycerol marinobacter adhaerens 39.0 39.0 2 PMID:29470619 -2.4.1.359 phosphate marinobacter adhaerens 14.0 14.0 1 PMID:29470619 -2.4.1.36 adp-glucose streptomyces venezuelae 29.0 29.0 1 PMID:27903647 -2.4.1.36 gdp-glucose streptomyces venezuelae 139.0 139.0 1 PMID:27903647 -2.4.1.36 glucose 6-phosphate streptomyces venezuelae 123.0 74.5 2 PMID:27903647 -2.4.1.360 2',4',6'-trihydroxyacetophenone fagopyrum esculentum 1.38 1.38 1 PMID:32699169 -2.4.1.360 2',4',6'-trihydroxydihydrochalcone oryza sativa indica group 0.75 0.75 1 PMID:19411659 -2.4.1.360 2,4,6-trihydroxybenzophenone oryza sativa indica group 0.11 0.11 1 PMID:19411659 -2.4.1.360 2,5,7-trihydroxyflavanone oryza sativa indica group 0.76 0.76 1 PMID:19411659 -2.4.1.360 2-hydroxyeriodictyol nelumbo lutea 0.18 0.09999999999999999 2 PMID:33486798 -2.4.1.360 2-hydroxynaringenin citrus japonica 7.6 7.6 1 PMID:28370711 -2.4.1.360 2-hydroxynaringenin nelumbo lutea 0.14 0.08 2 PMID:33486798 -2.4.1.360 2-hydroxynaringenin oryza sativa indica group 3.13 3.13 1 PMID:19411659 -2.4.1.360 6-beta-d-glucopyranosyl-2-hydroxynaringenin citrus japonica 5.7 5.7 1 PMID:28370711 -2.4.1.360 nothofagin citrus japonica 5.3 5.3 1 PMID:28370711 -2.4.1.360 phloretin citrus japonica 12.0 12.0 1 PMID:28370711 -2.4.1.360 phloretin fagopyrum esculentum 1.7 1.7 1 PMID:32699169 -2.4.1.360 phloretin oryza sativa indica group 10.84 10.84 1 PMID:19411659 -2.4.1.360 udp-alpha-d-glucose citrus japonica 0.8 0.8 1 PMID:28370711 -2.4.1.360 udp-alpha-d-glucose fagopyrum esculentum 3.13 2.58 2 PMID:32699169 -2.4.1.360 udp-galactose citrus japonica 0.0047 0.0047 1 PMID:39918272 -2.4.1.360 udp-galactose fagopyrum esculentum 1.35 0.99 2 PMID:32699169 -2.4.1.360 udp-glucose citrus japonica 2.32 2.32 1 PMID:39918272 -2.4.1.360 udp-xylose citrus japonica 0.25 0.25 1 PMID:39918272 -2.4.1.362 sucrose leuconostoc citreum 949.0 515.2 2 PMID:26763236 -2.4.1.363 (20s)-protopanaxadiol panax ginseng 17.9 17.9 1 PMID:26032089 -2.4.1.364 (20s)-protopanaxadiol panax ginseng 5.56e-05 5.56e-05 1 PMID:25320211 -2.4.1.364 ginsenoside c-k panax ginseng 0.0001347 0.0001347 1 PMID:25320211 -2.4.1.364 protopanaxadiol panax major 1.408 1.408 1 PMID:39888435 -2.4.1.365 (20s)-ginsenoside rh2 panax ginseng 1111.5 560.05 2 PMID:25320211;PMID:39120838 -2.4.1.365 ginsenoside f2 panax ginseng 0.41 0.41 1 PMID:25320211 -2.4.1.367 (20s)-protopanaxatriol panax ginseng 9.1 9.1 1 PMID:26032089 -2.4.1.368 calenduloside e panax ginseng 0.025 0.013000000000000001 2 PMID:35148079 -2.4.1.368 chikusetsusaponin iva panax ginseng 0.002 0.002 1 PMID:35148079 -2.4.1.368 glycyrrhetinic acid barbarea vulgaris 0.091 0.091 1 * -2.4.1.368 luteolin entada phaseoloides 1.16 1.16 1 PMID:40523485 -2.4.1.368 oleanolic acid panax ginseng 0.034 0.034 1 PMID:35148079 -2.4.1.368 quercetin entada phaseoloides 5.93 5.93 1 PMID:40523485 -2.4.1.368 udp-alpha-d-glucose barbarea vulgaris 0.102 0.102 1 * -2.4.1.368 zingibroside r1 panax ginseng 0.054 0.054 1 PMID:35148079 -2.4.1.369 diglucosyl-enterobactin salmonella enterica 0.383 0.383 1 PMID:39718537 -2.4.1.369 enterobactin escherichia coli o6:h1 0.18 0.18 1 PMID:15598734 -2.4.1.369 enterobactin salmonella enterica 0.783 0.783 1 PMID:39718537 -2.4.1.369 mecam salmonella enterica 0.2 0.2 1 PMID:39718537 -2.4.1.369 monoglucosyl-enterobactin salmonella enterica 0.7 0.7 1 PMID:39718537 -2.4.1.369 monoglucosyl-mecam salmonella enterica 0.063 0.063 1 PMID:39718537 -2.4.1.369 monoglucosyl-trencam salmonella enterica 0.257 0.257 1 PMID:39718537 -2.4.1.369 trencam salmonella enterica 0.383 0.383 1 PMID:39718537 -2.4.1.369 udp-alpha-d-glucose escherichia coli o6:h1 0.16 0.16 1 PMID:15598734 -2.4.1.37 alpha-fuc-(1->2)-beta-d-gal-(ch2)7ch3 homo sapiens 5.1 5.1 1 PMID:29873711 -2.4.1.37 alpha-l-fucp-(1,2)-beta-d-galp-(1,3)-beta-d-glcnacp-o(ch2)7ch3 homo sapiens 0.5 0.5 1 PMID:16326711 -2.4.1.37 alpha-l-fucp-(1,2)-beta-d-galp-(1,4)-beta-d-glcnacp-o(ch2)8co2ch3 homo sapiens 1.2 1.2 1 PMID:16326711 -2.4.1.37 alpha-l-fucp-(1,2)-beta-d-galp-o(ch2)7ch3 homo sapiens 3.5 3.5 1 PMID:16326711 -2.4.1.37 beta-d-galactosyl-(1->4)-beta-d-glucosyl-(1<->1)-ceramide homo sapiens 7.3 3.855 2 PMID:20655926 -2.4.1.37 udp-d-galactose homo sapiens 5.1 5.1 1 PMID:15987364 -2.4.1.37 udp-gal homo sapiens 0.37 0.37 1 PMID:18405657 -2.4.1.37 udp-galactose homo sapiens 5.2 5.1 12 PMID:10092863;PMID:12529355;PMID:17138593;PMID:17259183;PMID:17465952;PMID:9162041 -2.4.1.37 udp-galnac homo sapiens 5.1 5.1 1 PMID:18405657 -2.4.1.37 udp-glucose homo sapiens 0.002 0.0009649999999999999 4 PMID:10724530;PMID:17138593 -2.4.1.37 udp-n-acetylgalactosamine homo sapiens 0.42 0.2125 2 PMID:10092863;PMID:17259183;PMID:9162041 -2.4.1.38 4-methylumbelliferyl beta-d-xylopyranoside homo sapiens 1.13 1.13 1 PMID:19032152 -2.4.1.38 4-methylumbelliferyl-beta-d-xylopyranoside homo sapiens 1.51 1.51 1 PMID:25568325 -2.4.1.38 4-nitrophenyl beta-d-xylopyranoside homo sapiens 1.52 1.52 1 PMID:19032152 -2.4.1.38 chitotriose homo sapiens 4.81 4.055 2 PMID:16157350 -2.4.1.38 glcnacbeta1,2-manalpha1,3-manbeta-or homo sapiens 2.47 2.47 1 PMID:16157350 -2.4.1.38 glcnacbeta1,2-manalpha1,6 (glcnacbeta1,2-manalpha1,3)man homo sapiens 1.74 1.74 1 PMID:16157350 -2.4.1.38 glcnacbeta1,2-manalpha1,6-manbeta-or homo sapiens 1.9 1.9 1 PMID:16157350 -2.4.1.38 glcnacbeta1,4-manalpha1,3-manbeta-or homo sapiens 3.35 3.35 1 PMID:16157350 -2.4.1.38 n-acetyl-beta-d-glucosamine homo sapiens 3.6 3.6 1 PMID:16157350 -2.4.1.38 n-acetyl-beta-d-glucosaminyl-1,4-n-acetyl-beta-d-glucosamine homo sapiens 4.82 4.82 1 PMID:16157350 -2.4.1.38 n-acetylglucosamine bos taurus 14.0 0.25 3 PMID:15736931 -2.4.1.38 udp-alpha-d-galactose homo sapiens 1.51 1.51 1 PMID:25568325 -2.4.1.38 udp-galactose bos taurus 14.0 14.0 1 PMID:15736931 -2.4.1.38 udp-galactose homo sapiens 1.14 1.14 1 PMID:19032152 -2.4.1.38 udp-glucose bos taurus 0.25 0.155 2 PMID:15736931 -2.4.1.38 udp-glucose homo sapiens 0.02 0.02 1 PMID:19032152 -2.4.1.38 udp-glucuronic acid homo sapiens 0.003 0.003 1 PMID:19032152 -2.4.1.38 udp-n-acetyl-alpha-d-glucosamine homo sapiens 0.003 0.003 1 PMID:19032152 -2.4.1.38 udp-xylose homo sapiens 0.01 0.01 1 PMID:19032152 -2.4.1.384 apigenin bacillus subtilis 1.9 1.9 1 PMID:28315700 -2.4.1.384 genistein bacillus subtilis 1.6 1.6 1 PMID:28315700 -2.4.1.388 alpha-d-glucopyranose 1-phosphate paenibacillus polymyxa 69.0 69.0 1 PMID:34541742 -2.4.1.388 beta-d-glucosyl-(1->4)-d-galactose paenibacillus polymyxa 6.0 6.0 1 PMID:34541742 -2.4.1.388 d-galactopyranose paenibacillus polymyxa 57.0 57.0 1 PMID:34541742 -2.4.1.388 l-arabinose paenibacillus polymyxa 151.0 151.0 1 PMID:34541742 -2.4.1.388 phosphate paenibacillus polymyxa 34.0 34.0 1 PMID:34541742 -2.4.1.389 alpha-d-glucose 1-phosphate paenibacillus borealis 14.5 14.5 1 PMID:34997180 -2.4.1.389 d-galactose paenibacillus borealis 3.23 3.23 1 PMID:34997180 -2.4.1.389 solabiose paenibacillus borealis 9.14 9.14 1 PMID:34997180 -2.4.1.390 amylose limosilactobacillus fermentum 0.4295 0.4295 1 PMID:39198197 -2.4.1.391 2-naphthyl-alpha-d-glucose ignavibacterium album 3.9 3.9 1 PMID:35065074 -2.4.1.391 4-nitrophenyl-alpha-d-glucose ignavibacterium album 5.0 5.0 1 PMID:35065074 -2.4.1.391 4-nitrophenyl-beta-d-glucose ignavibacterium album 0.46 0.46 1 PMID:35065074 -2.4.1.391 alpha-arbutin ignavibacterium album 8.7 8.7 1 PMID:35065074 -2.4.1.391 amygdalin ignavibacterium album 0.35 0.35 1 PMID:35065074 -2.4.1.391 benzyl-alpha-d-glucose ignavibacterium album 0.86 0.86 1 PMID:35065074 -2.4.1.391 beta-arbutin ignavibacterium album 1.4 1.4 1 PMID:35065074 -2.4.1.391 esculin ignavibacterium album 1.3 1.3 1 PMID:35065074 -2.4.1.391 ethyl-alpha-d-glucose ignavibacterium album 0.55 0.55 1 PMID:35065074 -2.4.1.391 gastrodin ignavibacterium album 0.49 0.49 1 PMID:35065074 -2.4.1.391 methyl-alpha-d-glucose ignavibacterium album 1.0 1.0 1 PMID:35065074 -2.4.1.391 methyl-beta-d-glucose ignavibacterium album 1.9 1.9 1 PMID:35065074 -2.4.1.391 phenyl-alpha-d-glucose ignavibacterium album 1.8 1.8 1 PMID:35065074 -2.4.1.391 salicin ignavibacterium album 0.88 0.88 1 PMID:35065074 -2.4.1.391 sophoropentaose ignavibacterium album 1.7 1.7 1 PMID:35065074 -2.4.1.391 sophorose ignavibacterium album 8.0 8.0 1 PMID:35065074 -2.4.1.391 sophorotetraose ignavibacterium album 4.8 4.8 1 PMID:35065074 -2.4.1.391 sophorotriose ignavibacterium album 18.0 18.0 1 PMID:35065074 -2.4.1.392 3-o-beta-d-glucopyranosyl-d-glucuronic acid paenibacillus borealis 102.0 102.0 1 PMID:35947916 -2.4.1.392 4-nitrophenyl beta-d-glucuronide paenibacillus borealis 433.0 433.0 1 PMID:35947916 -2.4.1.392 d-glucuronic acid paenibacillus borealis 351.0 351.0 1 PMID:35947916 -2.4.1.393 gdp-alpha-d-mannose mycolicibacterium hassiacum 0.048 0.0325 2 PMID:36707645 -2.4.1.393 propyl-alpha-d-mannopyranosyl-(1->4)-3-o-methyl-alpha-d-mannopyranosyl-(1->4)-3-o-methyl-alpha-d-mannopyranoside mycolicibacterium hassiacum 0.047 0.047 1 PMID:36707645 -2.4.1.393 propyl-alpha-d-mannopyranosyl-(1->4)-alpha-d-mannopyranosyl-(1->4)-alpha-d-mannopyranosyl-(1->4)-alpha-d-mannopyranoside mycolicibacterium hassiacum 0.025 0.025 1 PMID:36707645 -2.4.1.394 amylose limosilactobacillus reuteri 0.565 0.3545 2 PMID:35129339;PMID:38488047 -2.4.1.394 amylose v limosilactobacillus reuteri 36.22 22.64 2 PMID:26253678 -2.4.1.394 maltose limosilactobacillus reuteri 37.0 37.0 2 PMID:22361861 -2.4.1.395 amylose limosilactobacillus reuteri 0.144 0.144 1 PMID:35129339 -2.4.1.395 amylose streptococcus thermophilus 9.34 9.34 1 PMID:38785045 -2.4.1.395 sucrose limosilactobacillus reuteri 293.0 74.65 4 PMID:15256553 -2.4.1.4 4'-hydroxyflavanone deinococcus geothermalis 0.015 0.0094 2 PMID:31307576 -2.4.1.4 6-hydroxyflavanone deinococcus geothermalis 0.84 0.7749999999999999 2 PMID:31307576 -2.4.1.4 fructose bifidobacterium thermophilum 0.729 0.729 1 PMID:39476901 -2.4.1.4 hydroquinone xanthomonas campestris pv. campestris 23.9 23.9 1 PMID:30820723 -2.4.1.4 maltobiose neisseria polysaccharea 3.1 3.1 1 PMID:24801911 -2.4.1.4 maltopentaose neisseria polysaccharea 47.0 47.0 1 PMID:24801911 -2.4.1.4 maltotetraose neisseria polysaccharea 7.5 7.5 1 PMID:24801911 -2.4.1.4 maltotriose neisseria polysaccharea 4.8 4.8 1 PMID:24801911 -2.4.1.4 sucrose calidithermus terrae 86.4 86.4 1 PMID:39769124 -2.4.1.4 sucrose deinococcus geothermalis 7.22 4.16 3 PMID:32522959;PMID:39631600 -2.4.1.4 sucrose neisseria polysaccharea 47.0 1.3 11 PMID:10767427;PMID:24801911;PMID:28019698;PMID:28732882 -2.4.1.40 alpha-fuc-(1->2)-beta-d-gal-(ch2)7ch3 homo sapiens 17.5 17.5 2 PMID:27979997;PMID:29873711 -2.4.1.40 alpha-l-fucp-(1,2)-beta-d-galp-(1,3)-beta-dglcnacp-o(ch2)7ch3 homo sapiens 1.3 1.3 1 PMID:16326711 -2.4.1.40 alpha-l-fucp-(1,2)-beta-d-galp-(1,4)-beta-d-glcnacp-o-(ch2)8co2ch3 homo sapiens 1.8 1.8 1 PMID:16326711 -2.4.1.40 alpha-l-fucp-(1,2)-beta-d-galp-o(ch2)7ch3 homo sapiens 7.6 7.6 1 PMID:16326711 -2.4.1.40 udp-gal homo sapiens 0.000333 0.000333 1 PMID:10092863;PMID:9162041 -2.4.1.40 udp-galnac homo sapiens 0.292 0.18685 2 PMID:10092863;PMID:12529355;PMID:9162041 -2.4.1.40 udp-glcnac homo sapiens 0.00035 0.00035 1 PMID:10724530 -2.4.1.41 gagadddyavtpgpdddagag homo sapiens 0.892 0.892 1 PMID:37555669 -2.4.1.41 gagadddyavtpgpdddagag taeniopygia guttata 32.17 32.17 1 PMID:37555669 -2.4.1.41 gagadddyavtpgpgagagag homo sapiens 0.602 0.602 1 PMID:37555669 -2.4.1.41 gagadddyavtpgprrragag homo sapiens 0.568 0.568 1 PMID:37555669 -2.4.1.41 gagagagyavtpgpgagagag homo sapiens 1.302 1.302 1 PMID:37555669 -2.4.1.41 gagagagyavtpgpgagagag taeniopygia guttata 44.17 44.17 1 PMID:37555669 -2.4.1.41 gagagagyavtpgprrragag homo sapiens 4.42 2.314 2 PMID:37555669 -2.4.1.41 gagarrryavtpgprrragag homo sapiens 2.0 2.0 1 PMID:37555669 -2.4.1.41 gagarrryavtpgprrragag taeniopygia guttata 47.67 47.67 1 PMID:37555669 -2.4.1.41 muc5ac homo sapiens 0.193 0.0525 6 PMID:18562306 -2.4.1.41 muc5ac-13 homo sapiens 0.4 0.139 8 PMID:18562306 -2.4.1.41 muc5ac-3 homo sapiens 0.33 0.184 8 PMID:18562306 -2.4.1.41 muc5ac-3,13 homo sapiens 1.4 0.76 3 PMID:18562306 -2.4.1.41 muc5ac-9 homo sapiens 0.127 0.127 1 PMID:18562306 -2.4.1.41 stpstpstpstpstp bos taurus 3.47 3.47 1 PMID:15377782 -2.4.1.41 udp-n-acetyl-alpha-d-galactosamine homo sapiens 0.813 0.813 1 PMID:31373799 -2.4.1.41 udp-n-acetyl-d-galactosamine bos taurus 3.47 3.47 1 PMID:15377782 -2.4.1.49 4-nitrophenyl beta-d-glucoside thermoclostridium stercorarium 19.6 19.6 1 PMID:21344678 -2.4.1.49 [(1->4)-beta-d-glucosyl]2 acetivibrio thermocellus 17.0 17.0 1 PMID:28760417 -2.4.1.49 [(1->4)-beta-d-glucosyl]3 acetivibrio thermocellus 9.5 9.5 1 PMID:28760417 -2.4.1.49 [(1->4)-beta-d-glucosyl]4 acetivibrio thermocellus 5.0 5.0 1 PMID:28760417 -2.4.1.49 [(1->4)-beta-d-glucosyl]5 acetivibrio thermocellus 1.9 1.9 1 PMID:28760417 -2.4.1.49 [(1->4)-beta-d-glucosyl]6 acetivibrio thermocellus 7.6 7.6 1 PMID:28760417 -2.4.1.49 alpha-d-galactose 1-phosphate thermoclostridium stercorarium 2.5 2.5 1 PMID:22000964 -2.4.1.49 alpha-d-glucose thermosipho africanus 30.3 30.3 1 PMID:28687766 -2.4.1.49 alpha-d-glucose 1-phosphate thermoclostridium stercorarium 27.4 27.4 2 PMID:21344678;PMID:22000964 -2.4.1.49 alpha-d-glucose 1-phosphate thermosipho africanus 7.61 7.61 1 PMID:28687766 -2.4.1.49 alpha-d-xylose thermosipho africanus 1.37 1.37 1 PMID:28687766 -2.4.1.49 cellobiose acetivibrio thermocellus 57.4 2.08 7 PMID:19879558;PMID:21630044;PMID:38863949 -2.4.1.49 cellobiose thermoclostridium stercorarium 18.1 18.1 1 PMID:21344678 -2.4.1.49 cellobiose thermosipho africanus 361.0 180.615 2 PMID:28687766 -2.4.1.49 celloheptaose acetivibrio thermocellus 4.53 2.84 10 PMID:21630044 -2.4.1.49 cellohexaose thermoclostridium stercorarium 6.1 6.1 1 PMID:9249035 -2.4.1.49 cellopentaose ruminiclostridium cellulolyticum 47.8 47.8 1 PMID:31497068 -2.4.1.49 cellopentaose thermoclostridium stercorarium 6.6 6.6 1 PMID:9249035 -2.4.1.49 cellopentaose thermosipho africanus 527.0 263.67 2 PMID:28687766 -2.4.1.49 cellotetraose acetivibrio thermocellus 3.2 3.2 1 PMID:19879558 -2.4.1.49 cellotetraose ruminiclostridium cellulolyticum 39.0 20.0 2 PMID:31497068 -2.4.1.49 cellotetraose thermoclostridium stercorarium 6.9 6.9 1 PMID:9249035 -2.4.1.49 cellotetraose thermosipho africanus 612.0 306.245 2 PMID:28687766 -2.4.1.49 cellotriose acetivibrio thermocellus 4.0 4.0 1 PMID:19879558 -2.4.1.49 cellotriose ruminiclostridium cellulolyticum 127.5 127.5 1 PMID:31497068 -2.4.1.49 cellotriose thermoclostridium stercorarium 2.7 2.7 1 PMID:9249035 -2.4.1.49 cellotriose thermosipho africanus 603.0 301.64 2 PMID:28687766 -2.4.1.49 octyl beta-d-glucoside thermoclostridium stercorarium 14.2 14.2 1 PMID:21344678 -2.4.1.49 phenyl beta-d-glucopyranoside acetivibrio thermocellus 15.0 15.0 1 PMID:28760417 -2.4.1.5 dextran leuconostoc mesenteroides 3.2 1.6425 2 * -2.4.1.5 sucrose leuconostoc mesenteroides 1070.0 97.41499999999999 8 PMID:17673948;PMID:21280619;PMID:29024683;PMID:34649690 -2.4.1.5 sucrose limosilactobacillus reuteri 0.6 0.6 1 PMID:33978404 -2.4.1.5 sucrose streptococcus oralis 22.4 22.4 1 PMID:18512955 -2.4.1.5 sucrose weissella confusa 60.0 41.6 2 PMID:23053097;PMID:25603169 -2.4.1.64 alpha,alpha-trehalose salisediminibacterium selenitireducens 210.0 210.0 1 PMID:24021648 -2.4.1.64 alpha-d-arabinose caldanaerobacter subterraneus subsp. pacificus 51.4 51.4 1 PMID:21803886 -2.4.1.64 alpha-d-galactose caldanaerobacter subterraneus subsp. pacificus 54.0 54.0 1 PMID:21803886 -2.4.1.64 alpha-d-xylose caldanaerobacter subterraneus subsp. pacificus 64.3 64.3 1 PMID:21803886 -2.4.1.64 alpha-l-fucose caldanaerobacter subterraneus subsp. pacificus 68.1 68.1 1 PMID:21803886 -2.4.1.64 beta-d-galactose 1-phosphate caldanaerobacter subterraneus 1.2 1.2 1 PMID:24909572 -2.4.1.64 beta-d-glucose 1-phosphate caldanaerobacter subterraneus 114.0 114.0 1 PMID:24909572 -2.4.1.64 beta-d-glucose 1-phosphate kocuria varians 660.0 660.0 1 * -2.4.1.64 beta-d-glucose 1-phosphate salisediminibacterium selenitireducens 68.0 68.0 1 PMID:24021648 -2.4.1.64 d-galactose caldanaerobacter subterraneus 113.0 113.0 1 PMID:24909572 -2.4.1.64 d-galactose thermoanaerobacter brockii 32.9 32.9 1 PMID:22848048 -2.4.1.64 d-glucose caldanaerobacter subterraneus 86.0 86.0 1 PMID:24909572 -2.4.1.64 d-glucose caldanaerobacter subterraneus subsp. pacificus 59.0 59.0 1 PMID:21803886 -2.4.1.64 d-glucose salisediminibacterium selenitireducens 60.0 60.0 1 PMID:24021648 -2.4.1.64 d-glucose thermoanaerobacter brockii 33.9 33.9 1 PMID:22848048 -2.4.1.64 glucose kocuria varians 660.0 660.0 1 * -2.4.1.64 phosphate kocuria varians 200.0 200.0 1 * -2.4.1.64 trehalose kocuria varians 200.0 200.0 1 * -2.4.1.65 fucalpha(1,2)galbeta(1,3)glcnac homo sapiens 8.02 8.02 1 PMID:9737989 -2.4.1.65 gal-beta-1,3glcnaco(ch2)3nhco(ch2)5nh-biotin homo sapiens 0.3 0.2 4 PMID:14977360 -2.4.1.65 galbeta(1,3)glcnac-(ch2)3-nhco-(ch2)5-nh-biotin homo sapiens 0.4 0.20450000000000002 2 PMID:11171070 -2.4.1.65 galbeta-(1-3)-glcnac-o-(ch2)8cooch3 helicobacter pylori 26.12 17.11 2 PMID:16000696 -2.4.1.65 galbeta1,3glcnac-o(ch2)8co2ch3 helicobacter pylori 1.1 1.1 1 PMID:16407247 -2.4.1.65 gdp-beta-l-fucose helicobacter pylori 3.947 3.13 3 PMID:16000696;PMID:16407247 -2.4.1.65 neuacalpha1-3galbeta1-3glcnac-beta-o-(ch2)8cooch3 helicobacter pylori 34.33 34.33 1 PMID:16000696 -2.4.1.68 n4-[n-acetyl-beta-d-glucosaminyl-(1-2)-alpha-d-mannosyl-(1-3)-[n-acetyl-beta-d-glucosaminyl-(1-2)-alpha-d-mannosyl-(1-6)]-beta-d-mannosyl-(1-4)-n-acetyl-beta-d-glucosaminyl-(1-4)-n-acetyl-beta-d-glucosaminyl]asparagine homo sapiens 0.45 0.45 1 PMID:22982178 -2.4.1.69 beta-lactose helicobacter pylori 0.2085 0.11524999999999999 2 PMID:36116126;PMID:38218286 -2.4.1.69 d-lactose escherichia coli 0.067 0.067 1 PMID:24249735 -2.4.1.69 gdp-beta-l-fucose escherichia coli 0.131 0.0985 2 PMID:18078329;PMID:24249735 -2.4.1.69 gdp-beta-l-fucose helicobacter pylori 0.152 0.0925 2 PMID:36116126;PMID:38218286 -2.4.1.69 gdp-l-fucose homo sapiens 0.007 0.007 1 PMID:22266267 -2.4.1.69 lactose escherichia coli 0.0497 0.0497 1 PMID:18078329 -2.4.1.69 lactulose escherichia coli 0.151 0.151 1 PMID:18078329 -2.4.1.69 methyl beta-d-galactopyranoside escherichia coli 0.0173 0.0173 1 PMID:18078329 -2.4.1.69 phenyl-beta-d-galactoside homo sapiens 0.011 0.011 1 PMID:22266267 -2.4.1.7 alpha-d-glucopyranosyl fluoride leuconostoc mesenteroides 121.0 121.0 1 PMID:21219904 -2.4.1.7 alpha-d-glucose 1-phosphate bifidobacterium adolescentis 121.1 121.1 1 * -2.4.1.7 alpha-d-glucose 1-phosphate bifidobacterium dentium 244.4 244.4 1 * -2.4.1.7 alpha-d-glucose 1-phosphate bifidobacterium longum 22.0 22.0 1 PMID:37253063 -2.4.1.7 alpha-d-glucose 1-phosphate leuconostoc mesenteroides 261.0 96.0 7 PMID:17215056;PMID:17233628;PMID:17350620;PMID:17659283;PMID:19691080;PMID:21219904 -2.4.1.7 alpha-d-glucose 1-phosphate streptococcus mutans 62.0 62.0 1 PMID:23613221 -2.4.1.7 arsenate leuconostoc mesenteroides 170.0 170.0 1 PMID:17350620;PMID:17659283 -2.4.1.7 d-fructose bifidobacterium adolescentis 129.4 129.4 1 * -2.4.1.7 d-fructose bifidobacterium dentium 291.7 291.7 1 * -2.4.1.7 d-fructose bifidobacterium longum 22.0 22.0 1 PMID:37253063 -2.4.1.7 d-fructose leuconostoc mesenteroides 72.0 72.0 2 PMID:17233628;PMID:17350620;PMID:17659283 -2.4.1.7 d-fructose streptococcus mutans 66.0 66.0 1 PMID:23613221 -2.4.1.7 glycerol leuconostoc mesenteroides 0.846 0.846 1 PMID:35398389 -2.4.1.7 glycerol limosilactobacillus reuteri 0.48 0.48 1 PMID:35398389 -2.4.1.7 l-ascorbic acid bifidobacterium breve 0.23 0.23 1 PMID:35739344 -2.4.1.7 phosphate bifidobacterium adolescentis 27600.0 27600.0 1 * -2.4.1.7 phosphate bifidobacterium dentium 51600.0 51600.0 1 * -2.4.1.7 phosphate bifidobacterium longum 84.0 84.0 1 PMID:37253063 -2.4.1.7 phosphate leuconostoc mesenteroides 200.0 195.0 3 PMID:17233628;PMID:17350620;PMID:17659283 -2.4.1.7 phosphate streptococcus mutans 153.0 153.0 1 PMID:23613221 -2.4.1.7 sucrose bifidobacterium adolescentis 19100.0 201.0 3 PMID:21900303;PMID:36857722 -2.4.1.7 sucrose bifidobacterium dentium 45200.0 45200.0 1 * -2.4.1.7 sucrose bifidobacterium longum 84.0 84.0 1 PMID:37253063 -2.4.1.7 sucrose leuconostoc mesenteroides 653.96 131.0 12 PMID:16797542;PMID:17215056;PMID:17233628;PMID:17350620;PMID:17659283;PMID:21219904;PMID:32924353;PMID:35398389 -2.4.1.7 sucrose leuconostoc mesenteroides subsp. mesenteroides 31.3 31.3 1 PMID:37380039 -2.4.1.7 sucrose limosilactobacillus reuteri 1.18 1.18 1 PMID:35398389 -2.4.1.7 sucrose streptococcus mutans 127.0 127.0 1 PMID:23613221 -2.4.1.7 sucrose thermoanaerobacterium thermosaccharolyticum 100.0 100.0 1 PMID:31978533 -2.4.1.7 sucrose thermobacillus sp. zcth02-b1 5.73 5.73 1 PMID:31470069 -2.4.1.7 sucrose uncultured bacterium 31.19 31.19 1 PMID:22806728 -2.4.1.8 1,5-anhydro-d-glucitol bacillus sp. ahu2001 1.12 1.12 1 PMID:31262243 -2.4.1.8 2-deoxy-d-glucose bacillus sp. ahu2001 39.2 39.2 1 PMID:31262243 -2.4.1.8 6-deoxy-d-glucose bacillus sp. ahu2001 69.1 69.1 1 PMID:31262243 -2.4.1.8 beta-d-glucose 1-phosphate paenibacillus sp. 43.5 43.5 1 * -2.4.1.8 d-allose bacillus sp. ahu2001 0.682 0.682 1 PMID:31262243 -2.4.1.8 d-glucosamine bacillus sp. ahu2001 237.0 237.0 1 PMID:31262243 -2.4.1.8 d-glucose bacillus sp. ahu2001 107.0 107.0 1 PMID:31262243 -2.4.1.8 d-glucose paenibacillus sp. 49.4 49.4 1 * -2.4.1.8 d-lyxose bacillus sp. ahu2001 0.436 0.436 1 PMID:31262243 -2.4.1.8 d-mannose bacillus sp. ahu2001 8.55 8.55 1 PMID:31262243 -2.4.1.8 d-xylose bacillus sp. ahu2001 29.9 29.9 1 PMID:31262243 -2.4.1.8 kojibiose bacillus sp. ahu2001 15.8 15.8 1 PMID:31262243 -2.4.1.8 kojibiose salisediminibacterium selenitireducens 40.0 40.0 1 PMID:22940176 -2.4.1.8 l-fucose bacillus sp. ahu2001 1.21 1.21 1 PMID:31262243 -2.4.1.8 l-sorbose bacillus sp. ahu2001 0.568 0.568 1 PMID:31262243 -2.4.1.8 maltose bacillus sp. ahu2001 30.9 30.9 1 PMID:31262243 -2.4.1.8 maltose paenibacillus sp. 17.3 17.3 1 * -2.4.1.8 maltose salisediminibacterium selenitireducens 12.3 12.3 1 PMID:22940176 -2.4.1.8 methyl alpha-d-glucoside bacillus sp. ahu2001 0.957 0.957 1 PMID:31262243 -2.4.1.8 phosphate paenibacillus sp. 12.9 12.9 1 * -2.4.1.8 sophorose salisediminibacterium selenitireducens 6.6 6.6 1 PMID:22940176 -2.4.1.81 4-coumaric acid erigeron breviscapus 0.0505 0.02395 6 PMID:30821967 -2.4.1.81 apigenin zea mays 0.99 0.99 1 PMID:39923422 -2.4.1.81 chrysin zea mays 0.73 0.73 1 PMID:39923422 -2.4.1.81 chrysoeriol zea mays 2.01 2.01 1 PMID:39923422 -2.4.1.81 daidzein glycine max 0.055 0.028 2 PMID:28633497 -2.4.1.81 eriodictyol zea mays 0.23 0.23 1 PMID:39923422 -2.4.1.81 genistein glycine max 0.039 0.022 2 PMID:28633497 -2.4.1.81 isorhamnetin marchantia paleacea 0.00832 0.00832 1 PMID:34166976 -2.4.1.81 isorhamnetin zea mays 1.3 1.3 1 PMID:39923422 -2.4.1.81 kaempferol marchantia paleacea 0.02066 0.02066 1 PMID:34166976 -2.4.1.81 kaempferol zea mays 1.18 1.18 1 PMID:39923422 -2.4.1.81 luteolin entada phaseoloides 1.16 1.16 1 PMID:40523485 -2.4.1.81 luteolin zea mays 0.95 0.95 1 PMID:39923422 -2.4.1.81 myricetin glycine max 0.013 0.0125 2 PMID:28633497 -2.4.1.81 myricetin marchantia paleacea 0.06455 0.06455 1 PMID:34166976 -2.4.1.81 naringenin arachis hypogaea 0.18 0.18 1 PMID:38062387 -2.4.1.81 naringenin zea mays 0.87 0.87 1 PMID:39923422 -2.4.1.81 neoliquiritin arachis hypogaea 0.185 0.185 1 PMID:38062387 -2.4.1.81 quercetin entada phaseoloides 5.93 5.93 1 PMID:40523485 -2.4.1.81 quercetin glycine max 0.1 0.1 1 PMID:28633497 -2.4.1.81 quercetin marchantia paleacea 0.0043 0.0043 1 PMID:34166976 -2.4.1.81 quercetin zea mays 3.32 3.32 1 PMID:39923422 -2.4.1.83 gdp-mannose cricetulus griseus 2.9e-06 2.6e-06 2 PMID:15750789 -2.4.1.83 gdp-mannose saccharomyces cerevisiae 70.9 41.5 2 PMID:15548536 -2.4.1.85 1-hexanol sorghum bicolor 0.06 0.06 1 PMID:12946413 -2.4.1.85 2-hydroxy-3-methoxybenzyl alcohol sorghum bicolor 0.39 0.39 1 PMID:12946413 -2.4.1.85 3-methyl-2-buten-1-ol sorghum bicolor 0.91 0.91 1 PMID:12946413 -2.4.1.85 3-methyl-3-buten-1-ol sorghum bicolor 0.07 0.07 1 PMID:12946413 -2.4.1.85 beta-citronellol sorghum bicolor 0.09 0.09 1 PMID:12946413 -2.4.1.85 cis-3-hexen-1-ol sorghum bicolor 0.03 0.03 1 PMID:12946413 -2.4.1.85 geraniol sorghum bicolor 0.1 0.1 1 PMID:12946413 -2.4.1.85 mandelonitrile sorghum bicolor 10.6 10.6 1 PMID:12946413 -2.4.1.85 nerol sorghum bicolor 0.06 0.06 1 PMID:12946413 -2.4.1.85 udp-glucose sorghum bicolor 8.9 8.9 1 PMID:16169969 -2.4.1.87 d-galactose bos taurus 0.32 0.32 1 PMID:19486884 -2.4.1.87 lactose bos taurus 6.4 6.4 1 PMID:14621997 -2.4.1.87 n-acetyllactosamine bos taurus 1.9 1.9 1 PMID:19486884 -2.4.1.87 p-nitrophenyl-alpha-d-galactoside bos taurus 0.059 0.059 1 PMID:19486884 -2.4.1.87 p-nitrophenyl-beta-d-galactoside bos taurus 1.1 1.1 1 PMID:19486884 -2.4.1.87 udp-galactose bos taurus 6.4 3.4 5 PMID:14621997;PMID:18782853;PMID:19245254 -2.4.1.9 sucrose leuconostoc citreum 425.0 67.25 8 PMID:18237396;PMID:39214229 -2.4.1.9 sucrose limosilactobacillus reuteri 729.0 90.45 12 PMID:12527388;PMID:37688600 -2.4.1.9 sucrose streptomyces viridochromogenes 3.5 3.5 1 PMID:28714842 -2.4.1.90 udp-alpha-d-galactose homo sapiens 0.059 0.059 1 PMID:30352055 -2.4.1.90 udp-galactose bos taurus 3.6 3.6 1 PMID:15449940 -2.4.1.91 2,3,4-trihydroxy benzoate raphanus sativus 3.098 3.098 1 PMID:38416725 -2.4.1.91 2,4,6-trihydroxy benzoate raphanus sativus 4.593 4.593 1 PMID:38416725 -2.4.1.91 2,4-dihydroxy benzoate raphanus sativus 2.061 2.061 1 PMID:38416725 -2.4.1.91 2,5-dihydroxy benzoate raphanus sativus 0.572 0.572 1 PMID:38416725 -2.4.1.91 3,4-dihydroxy benzoate raphanus sativus 1.36 1.36 1 PMID:38416725 -2.4.1.91 4-hydroxy benzoate raphanus sativus 0.953 0.953 1 PMID:38416725 -2.4.1.91 apigenin marchantia emarginata 0.00189 0.00189 1 PMID:34166976 -2.4.1.91 cyanidin vitis labrusca 0.000702 0.000702 1 PMID:22098678 -2.4.1.91 isorhamnetin marchantia emarginata 0.01687 0.01137 2 PMID:34166976 -2.4.1.91 kaempferol camellia sinensis 6.75 6.75 1 PMID:26941235 -2.4.1.91 kaempferol citrus x paradisi 1.34 1.28 3 PMID:19733370;PMID:32213838 -2.4.1.91 kaempferol glycine max 1.25 1.25 1 PMID:20621794 -2.4.1.91 kaempferol marchantia emarginata 0.03859 0.023325 2 PMID:34166976 -2.4.1.91 luteolin marchantia emarginata 0.01464 0.01464 1 PMID:34166976 -2.4.1.91 myricetin camellia sinensis 3.11 3.11 1 PMID:26941235 -2.4.1.91 myricetin citrus x paradisi 0.6252 0.6252 1 PMID:19733370 -2.4.1.91 myricetin marchantia emarginata 0.01258 0.010265 2 PMID:34166976 -2.4.1.91 quercetin camellia sinensis 3.32 3.32 1 PMID:26941235 -2.4.1.91 quercetin citrus x paradisi 1.84 1.54 3 PMID:19733370;PMID:32213838 -2.4.1.91 quercetin marchantia emarginata 0.04515 0.026510000000000002 2 PMID:34166976 -2.4.1.91 quercetin vitis labrusca 0.000113 0.000113 1 PMID:22098678 -2.4.1.91 udp-alpha-d-glucose vitis labrusca 0.000247 0.000247 1 PMID:22098678 -2.4.1.91 udp-glucose camellia sinensis 3.61 3.61 1 PMID:26941235 -2.4.1.91 udp-glucose citrus x paradisi 1.442 0.738 3 PMID:19733370;PMID:32213838 -2.4.1.91 udp-glucose raphanus sativus 1.98 1.98 1 PMID:38416725 -2.4.1.97 alpha-d-glucose euglena gracilis var. saccharophila 1.1 1.1 1 PMID:29317507 -2.4.1.97 alpha-d-glucose 1-phosphate thermosipho africanus 7.6 7.6 1 PMID:33970317 -2.4.1.97 cellobiose thermosipho africanus 361.0 361.0 1 PMID:33970317 -2.4.1.97 cellopentaose thermosipho africanus 527.0 527.0 1 PMID:33970317 -2.4.1.97 cellotetraose thermosipho africanus 612.0 612.0 1 PMID:33970317 -2.4.1.97 cellotriose thermosipho africanus 603.0 603.0 1 PMID:33970317 -2.4.1.97 d-glucose thermosipho africanus 30.3 30.3 1 PMID:33970317 -2.4.1.97 laminaribiose euglena gracilis var. saccharophila 1.08 1.08 1 PMID:29317507 -2.4.1.97 laminaribiose paenibacillus polymyxa 32.0 32.0 1 PMID:33970317 -2.4.1.97 laminarihexaose euglena gracilis var. saccharophila 1.1 1.1 1 PMID:29317507 -2.4.1.97 laminarihexaose paenibacillus polymyxa 30.0 30.0 1 PMID:33970317 -2.4.1.97 laminaripentaose euglena gracilis var. saccharophila 1.13 1.13 1 PMID:29317507 -2.4.1.97 laminaripentaose paenibacillus polymyxa 27.0 27.0 1 PMID:33970317 -2.4.1.97 laminaritetraose euglena gracilis var. saccharophila 1.12 1.12 1 PMID:29317507 -2.4.1.97 laminaritetraose paenibacillus polymyxa 33.0 33.0 1 PMID:33970317 -2.4.1.97 laminaritriose euglena gracilis var. saccharophila 1.12 1.12 1 PMID:29317507 -2.4.1.97 laminaritriose ochromonas danica 400.0 400.0 1 PMID:24018693 -2.4.1.97 laminaritriose paenibacillus polymyxa 33.0 33.0 1 PMID:33970317 -2.4.1.97 xylose thermosipho africanus 1.4 1.4 1 PMID:33970317 -2.4.1.99 sucrose agave tequilana 4.3 4.3 1 * -2.4.1.99 sucrose aspergillus aculeatus 16200.0 8487.5 2 PMID:17056145 -2.4.2.1 2',3'-dideoxyinosine homo sapiens 0.9 0.9 1 PMID:20525731 -2.4.2.1 2'-deoxyguanosine anopheles gambiae 5.4 5.4 1 PMID:17918964 -2.4.2.1 2'-deoxyguanosine bos taurus 45.0 45.0 1 PMID:1445943 -2.4.2.1 2'-deoxyguanosine mycobacterium tuberculosis 5.1 5.1 1 PMID:19416718 -2.4.2.1 2'-deoxyguanosine thermus thermophilus 830.0 830.0 1 PMID:22344645 -2.4.2.1 2'-deoxyinosine anopheles gambiae 54.0 54.0 1 PMID:17918964 -2.4.2.1 2'-deoxyinosine bos taurus 85.0 85.0 1 PMID:1445943 -2.4.2.1 2'-deoxyinosine mycobacterium tuberculosis 7.5 7.5 1 PMID:19416718 -2.4.2.1 2'-deoxyinosine plasmodium falciparum 0.9 0.9 1 PMID:18758447 -2.4.2.1 2'-deoxyinosine plasmodium yoelii 1.2 1.2 1 PMID:18758447 -2.4.2.1 2'-deoxyinosine thermus thermophilus 627.0 627.0 1 PMID:22344645 -2.4.2.1 2-amino-6-mercapto-7-methylpurine ribonucleoside mycobacterium tuberculosis 17.3 17.3 1 PMID:19416718 -2.4.2.1 2-amino-6-mercapto-7-methylpurine ribonucleoside plasmodium falciparum 2.4 2.4 1 PMID:33075341 -2.4.2.1 2-fluoro-2'-deoxyadenosine escherichia coli 2.77 2.77 1 PMID:12937174 -2.4.2.1 2-fluoroadenosine escherichia coli 2.05 2.05 1 PMID:12937174 -2.4.2.1 5'-methylthioadenosine plasmodium falciparum 2.6 2.6 1 PMID:16829527 -2.4.2.1 5'-methylthioadenosine toxoplasma gondii 0.027 0.027 1 PMID:16829527 -2.4.2.1 5'-methylthioinosine plasmodium falciparum 0.83 0.83 1 PMID:24416224 -2.4.2.1 7-methylguanosine homo sapiens 73.1 21.7 6 PMID:18938130 -2.4.2.1 7-methylinosine cellulomonas sp. 27.5 27.5 1 PMID:11437593 -2.4.2.1 7-methylinosine escherichia coli 2.57 2.57 1 PMID:11437593 -2.4.2.1 7-methylinosine mycobacterium tuberculosis 18.0 18.0 1 PMID:19416718 -2.4.2.1 9-beta-d-(2-deoxyribofuranosyl)-6-methylthiopurine escherichia coli 9.7 9.7 1 PMID:12937174 -2.4.2.1 9-beta-d-ribofuranosyl-6-methylthiopurine escherichia coli 1.1 1.1 1 PMID:12937174 -2.4.2.1 adenosine aeropyrum pernix 3450.0 1735.0 2 PMID:23160980;PMID:23332162 -2.4.2.1 adenosine aneurinibacillus migulanus 14.3 14.3 1 PMID:31888088 -2.4.2.1 adenosine escherichia coli 3.3 3.3 1 PMID:12937174 -2.4.2.1 adenosine thermus thermophilus 0.55 0.55 1 PMID:23546840 -2.4.2.1 adenosine trichomonas vaginalis 1.7 1.7 1 PMID:17223688 -2.4.2.1 alpha-d-deoxyribose 1-phosphate bos taurus 145.0 130.0 2 PMID:1445943 -2.4.2.1 alpha-d-ribose 1-phosphate bos taurus 120.0 110.0 2 PMID:1445943 -2.4.2.1 deoxyinosine plasmodium falciparum 0.89 0.89 1 PMID:16829527 -2.4.2.1 deoxyinosine toxoplasma gondii 0.48 0.48 1 PMID:16829527 -2.4.2.1 guanine bos taurus 158.0 142.5 2 PMID:1445943 -2.4.2.1 guanine homo sapiens 48.0 48.0 1 PMID:17348834 -2.4.2.1 guanosine aeropyrum pernix 876.0 876.0 1 PMID:23160980 -2.4.2.1 guanosine aneurinibacillus migulanus 18400.0 18400.0 1 PMID:31888088 -2.4.2.1 guanosine anopheles gambiae 1.0 1.0 1 PMID:17918964 -2.4.2.1 guanosine bos taurus 59.0 43.0 2 PMID:1445943;PMID:18281956 -2.4.2.1 guanosine halalkalibacterium halodurans 12.0 12.0 1 PMID:20063024 -2.4.2.1 guanosine homo sapiens 31.0 8.7 5 PMID:17348834;PMID:18281956;PMID:26305965;PMID:28584087 -2.4.2.1 guanosine kluyveromyces lactis 29.7 29.7 1 PMID:27768715 -2.4.2.1 guanosine mycobacterium tuberculosis 4.0 4.0 1 PMID:19416718 -2.4.2.1 guanosine plasmodium falciparum 2.6 2.6 2 PMID:16829527;PMID:18758447 -2.4.2.1 guanosine plasmodium yoelii 3.8 3.8 1 PMID:18758447 -2.4.2.1 guanosine pyrococcus furiosus 28.05 28.05 1 PMID:17419725 -2.4.2.1 guanosine thermus thermophilus 296.0 148.13 2 PMID:22344645;PMID:23546840 -2.4.2.1 guanosine toxoplasma gondii 3.6 3.6 1 PMID:16829527 -2.4.2.1 guanosine trichomonas vaginalis 1.1 1.1 1 PMID:17223688 -2.4.2.1 hypoxanthine bos taurus 127.0 115.0 2 PMID:1445943 -2.4.2.1 hypoxanthine homo sapiens 110.0 110.0 2 PMID:17348834;PMID:9305962 -2.4.2.1 inosine aeropyrum pernix 838.0 430.5 2 PMID:23160980;PMID:23332162 -2.4.2.1 inosine agaricus bisporus var. burnettii 14.38 14.38 1 PMID:40278089 -2.4.2.1 inosine aneurinibacillus migulanus 63800.0 63800.0 1 PMID:31888088 -2.4.2.1 inosine anopheles gambiae 41.0 41.0 1 PMID:17918964 -2.4.2.1 inosine bacillus subtilis 12000.0 7950.0 2 PMID:21279421 -2.4.2.1 inosine bos taurus 119.0 32.0 4 PMID:1445943;PMID:17348834;PMID:18281956;PMID:18281958 -2.4.2.1 inosine escherichia coli 6200.0 74.915 4 PMID:12937174;PMID:18299797;PMID:21279421 -2.4.2.1 inosine halalkalibacterium halodurans 28000.0 28000.0 1 PMID:20063024 -2.4.2.1 inosine homo sapiens 56.0 35.5 10 PMID:14982926;PMID:17348834;PMID:17407325;PMID:18281956;PMID:18281958;PMID:20525731;PMID:27769382;PMID:9305962 -2.4.2.1 inosine kluyveromyces lactis 43.9 43.9 1 PMID:27768715 -2.4.2.1 inosine mus musculus 47.3 43.099999999999994 2 * -2.4.2.1 inosine mycobacterium tuberculosis 15.7 10.55 2 PMID:19416718;PMID:27769382 -2.4.2.1 inosine plasmodium falciparum 2.6 1.45 8 PMID:14982926;PMID:16829527;PMID:18758447;PMID:24416224;PMID:24585883;PMID:33075341;PMID:33524395 -2.4.2.1 inosine plasmodium yoelii 3.5 3.5 1 PMID:18758447 -2.4.2.1 inosine pseudoalteromonas sp. 7000.0 98.85 4 PMID:18299797;PMID:21279421;PMID:22579392 -2.4.2.1 inosine pyrococcus furiosus 84.19 84.19 1 PMID:17419725 -2.4.2.1 inosine thermus thermophilus 173.0 173.0 1 PMID:22344645 -2.4.2.1 inosine toxoplasma gondii 2.6 1.415 2 PMID:16829527;PMID:24585883 -2.4.2.1 inosine trichomonas vaginalis 1.8 1.8 1 PMID:17223688 -2.4.2.1 methylthioinosine homo sapiens 0.2 0.2 1 PMID:14982926 -2.4.2.1 methylthioinosine plasmodium falciparum 2.6 2.05 2 PMID:14982926;PMID:18758447 -2.4.2.1 methylthioinosine plasmodium yoelii 3.4 3.4 1 PMID:18758447 -2.4.2.1 p-nitrophenyl beta-d-ribofuranoside trichomonas vaginalis 1.0 0.5005 2 PMID:17223688 -2.4.2.1 phosphate cellulomonas sp. 27.8 27.8 1 PMID:11437593 -2.4.2.1 phosphate escherichia coli 104.9 44.93 3 PMID:11437593;PMID:18299797 -2.4.2.1 phosphate homo sapiens 76.0 56.0 3 PMID:17348834;PMID:27769382;PMID:9305962 -2.4.2.1 phosphate mycobacterium tuberculosis 17.9 4.9 7 PMID:19416718;PMID:27769382 -2.4.2.1 phosphate plasmodium falciparum 2.4 1.7999999999999998 2 PMID:33075341 -2.4.2.1 phosphate pseudoalteromonas sp. 113.6 113.6 1 PMID:18299797 -2.4.2.1 uridine plasmodium falciparum 0.09 0.09 1 PMID:16829527 -2.4.2.1 xanthosine bos taurus 4.0 4.0 1 PMID:1445943 -2.4.2.1 xanthosine kluyveromyces lactis 16.8 16.8 1 PMID:27768715 -2.4.2.10 5-fluoroorotate plasmodium falciparum 4.0 4.0 1 PMID:15003844 -2.4.2.10 5-phospho-alpha-d-ribose 1-diphosphate burkholderia cenocepacia 0.017 0.017 1 PMID:39938730 -2.4.2.10 5-phospho-alpha-d-ribose 1-diphosphate plasmodium falciparum 3534.0 5.5 4 PMID:15003844;PMID:28389349 -2.4.2.10 diphosphate mycobacterium tuberculosis 0.28 0.28 1 PMID:22075667 -2.4.2.10 diphosphate plasmodium falciparum 1.3 1.3 1 PMID:15003844 -2.4.2.10 orotate burkholderia cenocepacia 0.12 0.12 1 PMID:39938730 -2.4.2.10 orotate escherichia coli 26.4 26.4 1 * -2.4.2.10 orotate mycobacterium tuberculosis 0.61 0.605 2 PMID:22075667 -2.4.2.10 orotate plasmodium falciparum 3534.0 6.0 9 PMID:15003844;PMID:15147974;PMID:15683248;PMID:28389349 -2.4.2.10 orotidine homo sapiens 0.024 0.024 1 PMID:20527751 -2.4.2.10 orotidine plasmodium falciparum 0.042 0.042 1 PMID:20527751 -2.4.2.10 orotidine 5'-phosphate homo sapiens 0.1 0.0585 2 PMID:19292447 -2.4.2.10 orotidine 5'-phosphate mycobacterium tuberculosis 0.28 0.28 1 PMID:22075667 -2.4.2.10 orotidine 5'-phosphate plasmodium falciparum 2.6 1.96 3 PMID:15003844;PMID:19292447 -2.4.2.10 phosphonoacetic acid homo sapiens 0.017 0.017 1 PMID:19292447 -2.4.2.10 phosphonoacetic acid plasmodium falciparum 0.023 0.023 1 PMID:19292447 -2.4.2.12 atp homo sapiens 0.0433 0.010585 6 PMID:18823127 -2.4.2.12 nicotinamide homo sapiens 0.00767 0.00142 3 PMID:18823127 -2.4.2.12 nicotinamide mus musculus 0.02 0.02 1 PMID:15381699 -2.4.2.17 1-(5-phospho-beta-d-ribosyl)-atp acinetobacter baumannii 2.95 2.95 1 PMID:38582930 -2.4.2.17 5-phospho-alpha-d-ribose 1-diphosphate campylobacter jejuni 1.8 1.8 3 PMID:27191057;PMID:29208762 -2.4.2.17 5-phospho-alpha-d-ribose 1-diphosphate corynebacterium glutamicum 1.91 1.91 1 PMID:22172596 -2.4.2.17 5-phospho-alpha-d-ribose 1-diphosphate lactococcus lactis 2.7 2.7 1 PMID:17154531 -2.4.2.17 5-phospho-alpha-d-ribose 1-diphosphate medicago truncatula 0.57 0.57 1 PMID:30072492 -2.4.2.17 5-phospho-alpha-d-ribose 1-diphosphate psychrobacter arcticus 1.72 0.94 6 PMID:28092443;PMID:36494361 -2.4.2.17 adp acinetobacter baumannii 16.6 3.3 3 PMID:38150593 -2.4.2.17 atp acinetobacter baumannii 10.8 1.945 4 PMID:38150593;PMID:38582930 -2.4.2.17 atp campylobacter jejuni 1.8 0.912 2 PMID:29208762 -2.4.2.17 atp medicago truncatula 0.57 0.57 1 PMID:30072492 -2.4.2.17 atp psychrobacter arcticus 1.72 0.94 6 PMID:28092443;PMID:36494361 -2.4.2.18 3-hydroxyanthranilate arabidopsis thaliana 0.048 0.048 1 PMID:37659723 -2.4.2.18 3-hydroxyanthranilate citrus sinensis 0.038 0.038 1 PMID:37659723 -2.4.2.18 3-hydroxyanthranilate juglans regia 0.048 0.048 1 PMID:37659723 -2.4.2.18 3-hydroxyanthranilate physcomitrium patens 0.053 0.053 1 PMID:37659723 -2.4.2.18 3-hydroxyanthranilate pistacia vera 0.035 0.035 1 PMID:37659723 -2.4.2.18 3-hydroxyanthranilate selaginella moellendorffii 0.053 0.053 1 PMID:37659723 -2.4.2.18 5-phospho-alpha-d-ribose 1-diphosphate acetomicrobium mobile 0.00016 0.00016 1 PMID:31134642 -2.4.2.18 5-phospho-alpha-d-ribose 1-diphosphate coprococcus eutactus 0.27 0.27 1 PMID:31134642 -2.4.2.18 5-phospho-alpha-d-ribose 1-diphosphate escherichia coli 4.4 4.4 1 PMID:2428387 -2.4.2.18 5-phospho-alpha-d-ribose 1-diphosphate fructobacillus fructosus 0.44 0.44 1 PMID:31134642 -2.4.2.18 5-phospho-alpha-d-ribose 1-diphosphate methanocella conradii 0.13 0.13 1 PMID:31134642 -2.4.2.18 5-phospho-alpha-d-ribose 1-diphosphate methanococcus voltae 0.00067 0.00067 1 PMID:31134642 -2.4.2.18 5-phospho-alpha-d-ribose 1-diphosphate pelodictyon luteolum 0.28 0.28 1 PMID:31134642 -2.4.2.18 5-phospho-alpha-d-ribose 1-diphosphate petrotoga mobilis 0.25 0.25 1 PMID:31134642 -2.4.2.18 5-phospho-alpha-d-ribose 1-diphosphate saccharolobus solfataricus 4.2 0.1425 8 PMID:11298741;PMID:16714288;PMID:31134642 -2.4.2.18 5-phospho-alpha-d-ribose 1-diphosphate staphylococcus aureus 0.43 0.43 1 PMID:31134642 -2.4.2.18 5-phospho-alpha-d-ribose 1-diphosphate staphylococcus haemolyticus 0.42 0.42 1 PMID:31134642 -2.4.2.18 anthranilate arabidopsis thaliana 0.132 0.132 1 PMID:37659723 -2.4.2.18 anthranilate citrus sinensis 0.117 0.117 1 PMID:37659723 -2.4.2.18 anthranilate escherichia coli 4.4 4.4 1 PMID:2428387 -2.4.2.18 anthranilate juglans regia 0.055 0.055 1 PMID:37659723 -2.4.2.18 anthranilate ogataea henricii 0.34 0.34 1 PMID:4315152 -2.4.2.18 anthranilate physcomitrium patens 0.057 0.057 1 PMID:37659723 -2.4.2.18 anthranilate pistacia vera 0.04 0.04 1 PMID:37659723 -2.4.2.18 anthranilate saccharolobus solfataricus 4.2 0.105 15 PMID:11298741;PMID:16714288;PMID:18164726;PMID:19385665 -2.4.2.18 anthranilate saccharomyces cerevisiae 2.9 2.9 1 PMID:2651124 -2.4.2.18 anthranilate salmonella enterica subsp. enterica serovar typhimurium 4.1 4.1 1 PMID:4315259;PMID:4358945 -2.4.2.18 anthranilate selaginella moellendorffii 0.085 0.085 1 PMID:37659723 -2.4.2.19 5-phospho-alpha-d-ribose 1-diphosphate mycobacterium tuberculosis 0.14 0.14 1 PMID:24949952 -2.4.2.19 pyridine-2,3-dicarboxylate streptococcus pyogenes 6.0 6.0 1 PMID:23204464 -2.4.2.19 quinolinic acid mycobacterium tuberculosis 0.12 0.12 1 PMID:24949952 -2.4.2.19 quinolinic acid salmonella enterica subsp. enterica serovar typhimurium 1.0 1.0 2 PMID:20047306;PMID:20047307 -2.4.2.2 4-thiothymidine escherichia coli 63.0 63.0 1 * -2.4.2.2 4-thiouridine escherichia coli 49.0 49.0 1 * -2.4.2.2 5-fluorodeoxyuridine mesomycoplasma hyorhinis 11.9 11.9 1 PMID:22475552 -2.4.2.2 5-fluorouridine mesomycoplasma hyorhinis 6.1 6.1 1 PMID:22475552 -2.4.2.2 5-iododeoxyuridine mesomycoplasma hyorhinis 9.5 9.5 1 PMID:22475552 -2.4.2.2 5-iodouridine mesomycoplasma hyorhinis 6.4 6.4 1 PMID:22475552 -2.4.2.2 5-trifluorothymidine mesomycoplasma hyorhinis 8.25 8.25 1 PMID:24940697 -2.4.2.2 deoxyuridine mesomycoplasma hyorhinis 24.6 24.6 1 PMID:22475552 -2.4.2.2 phosphate mesomycoplasma hyorhinis 17.5 13.05 2 PMID:22475552 -2.4.2.2 thymidine mesomycoplasma hyorhinis 21.6 21.05 2 PMID:22475552;PMID:24940697 -2.4.2.2 thymidine parageobacillus thermoglucosidasius 83.0 83.0 1 * -2.4.2.2 thymidine thermus thermophilus 679.0 679.0 1 * -2.4.2.2 uridine mesomycoplasma hyorhinis 9.03 8.765 2 PMID:22475552;PMID:24940697 -2.4.2.2 uridine parageobacillus thermoglucosidasius 277.0 277.0 1 * -2.4.2.2 uridine streptococcus pyogenes 15.0 15.0 1 PMID:21707079 -2.4.2.2 uridine thermus thermophilus 277.0 277.0 1 * -2.4.2.21 5,6-dimethylbenzimidazole sporomusa ovata 1.6 1.6 1 PMID:23039029 -2.4.2.21 beta-nicotinate d-ribonucleotide salmonella enterica 38.0 38.0 1 PMID:19880598 -2.4.2.21 nad+ salmonella enterica subsp. enterica serovar typhimurium 0.62 0.62 1 PMID:12686640 -2.4.2.21 nmn salmonella enterica subsp. enterica serovar typhimurium 149.0 149.0 1 PMID:12686640 -2.4.2.21 phenol sporomusa ovata 0.4 0.4 1 PMID:23039029 -2.4.2.22 5-phospho-alpha-d-ribose 1-diphosphate escherichia coli 112.0 112.0 1 PMID:9100006 -2.4.2.22 5-phospho-alpha-d-ribose 1-diphosphate leishmania donovani 3.9 2.95 4 PMID:19861168;PMID:34268726 -2.4.2.22 5-phospho-alpha-d-ribose 1-diphosphate plasmodium falciparum 1.6 0.9 2 PMID:27479359 -2.4.2.22 9-(5-phospho-beta-d-ribosyl)xanthine leishmania donovani 0.028 0.028 1 PMID:19861168 -2.4.2.22 diphosphate leishmania donovani 0.0228 0.0228 1 PMID:19861168 -2.4.2.22 guanine bacillus subtilis 0.03 0.03 1 PMID:16716072 -2.4.2.22 guanine escherichia coli 112.0 112.0 1 PMID:9100006 -2.4.2.22 guanine leishmania donovani 0.455 0.455 1 PMID:34268726 -2.4.2.22 hypoxanthine bacillus subtilis 0.5 0.5 1 PMID:16716072 -2.4.2.22 hypoxanthine escherichia coli 54.8 54.8 1 PMID:9100006 -2.4.2.22 hypoxanthine leishmania donovani 3.1 2.6 3 PMID:10567419;PMID:19861168;PMID:34268726 -2.4.2.22 xanthine bacillus subtilis 11.0 11.0 1 PMID:16716072 -2.4.2.22 xanthine escherichia coli 150.0 150.0 1 PMID:9100006 -2.4.2.22 xanthine leishmania donovani 3.5 2.65 2 PMID:19861168;PMID:34268726 -2.4.2.25 apigenin 7-o-beta-d-glucoside apium graveolens 0.00088 0.00088 1 PMID:37433052 -2.4.2.25 udp-alpha-d-apiose apium graveolens 0.00065 0.00065 1 PMID:37433052 -2.4.2.26 [syndecan 1]-l-serine homo sapiens 0.27 0.27 1 PMID:33899899 -2.4.2.26 [syndecan 3]-l-serine homo sapiens 0.05 0.05 1 PMID:33899899 -2.4.2.26 [syndecan 4]-l-serine homo sapiens 0.25 0.25 1 PMID:33899899 -2.4.2.26 biotin-nh-qeeegsgggqkk(5-fluorescein)-conh2 homo sapiens 0.0363 0.0363 1 PMID:19100717 -2.4.2.26 qeeegsgggqgg homo sapiens 0.47 0.47 1 PMID:33899899 -2.4.2.26 udp-6-azido-alpha-d-glucose homo sapiens 0.017 0.017 1 PMID:33899899 -2.4.2.26 udp-alpha-d-glucose homo sapiens 0.03 0.03 1 PMID:33899899 -2.4.2.26 udp-alpha-d-xylose homo sapiens 0.22 0.22 1 PMID:33899899 -2.4.2.28 2'-chloro-2'-deoxyadenosine trypanosoma brucei 6.4 6.4 1 PMID:27036940 -2.4.2.28 2'-deoxy-2'-azido-5'-deoxy-5'-methylthioadenosine homo sapiens 0.04 0.04 1 PMID:15911263 -2.4.2.28 2'-deoxy-2-fluoro-5'-deoxy-5'-methylthioadenosine homo sapiens 0.0004 0.0004 1 PMID:15911263 -2.4.2.28 2'-deoxy-5'-deoxy-5'-methylthioadenosine homo sapiens 0.28 0.28 1 PMID:15911263 -2.4.2.28 2'-deoxyadenosine schistosoma mansoni 224.3 224.3 1 PMID:27935959 -2.4.2.28 2'-fluoro-2'-deoxyadenosine trypanosoma brucei 5.4 5.4 1 PMID:27036940 -2.4.2.28 3'-deoxy-5'-deoxy-5'-methylthioadenosine homo sapiens 0.004 0.004 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-(1,3-thiazol)-2-yl-sulfanyladenosine homo sapiens 3.8 3.8 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-(2-(pyridin-2-yl)ethyl)-thioadenosine homo sapiens 2.14 2.14 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-(2-methylbutyl)-thioadenosine homo sapiens 5.5 5.5 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-(2-methylphenyl)-thioadenosine homo sapiens 2.4 2.4 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-(3-methylphenyl)-thioadenosine homo sapiens 1.4 1.4 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-(4-methoxyphenyl)-thioadenosine homo sapiens 1.5 1.5 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-(4-methylphenyl)-thioadenosine homo sapiens 0.3 0.3 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-(phenylethyl)-thioadenosine homo sapiens 2.5 2.5 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-(phenylmethyl)-thioadenosine homo sapiens 2.49 2.49 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-(quinolin-2-yl)-sulfanyladenosine homo sapiens 3.44 3.44 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-[4-(trifluoromethyl)phenyl]-thioadenosine homo sapiens 0.8 0.8 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-butylthioadenosine homo sapiens 2.3 2.3 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-cyclohexyl-thioadenosine homo sapiens 1.01 1.01 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-cyclopentyl-thioadenosine homo sapiens 1.57 1.57 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-ethylthioadenosine homo sapiens 0.67 0.67 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-hydroxyethylthioadenosine homo sapiens 5.9 5.9 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-imidazol-2-yl-sulfanyladenosine homo sapiens 1.5 1.5 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-isobutylthioadenosine homo sapiens 2.9 2.9 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-isopentylthioadenosine homo sapiens 0.85 0.85 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-methyl-thioadenosine homo sapiens 4.6 4.6 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-methylthioadenosine schistosoma mansoni 443.8 443.8 1 PMID:27935959 -2.4.2.28 5'-deoxy-5'-phenyl-thioadenosine homo sapiens 3.16 3.16 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-pyridin-2-yl-sulfanyladenosine homo sapiens 0.23 0.23 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-pyridin-4-yl-sulfanyladenosine homo sapiens 4.2 4.2 1 PMID:15911263 -2.4.2.28 5'-deoxy-5'-tert-butylthioadenosine homo sapiens 1.46 1.46 1 PMID:15911263 -2.4.2.28 5'-deoxy-adenosine homo sapiens 4.8 4.8 1 PMID:15911263 -2.4.2.28 5'-methylthioadenosine arabidopsis thaliana 18.7 10.35 2 PMID:18342331 -2.4.2.28 5'-methylthioadenosine mycobacterium tuberculosis 0.4 0.4 1 PMID:22225784 -2.4.2.28 5'-methylthioadenosine pyrococcus furiosus 24.5 24.5 1 PMID:12664268 -2.4.2.28 5'-methylthioadenosine saccharolobus solfataricus 21.4 21.4 1 PMID:15819883 -2.4.2.28 adenosine pyrococcus furiosus 22.8 22.8 1 PMID:12664268 -2.4.2.28 adenosine saccharolobus solfataricus 43.6 43.6 1 PMID:15819883 -2.4.2.28 adenosine schistosoma mansoni 334.1 334.1 1 PMID:27935959 -2.4.2.28 adenosine trypanosoma brucei 8.4 8.4 1 PMID:27036940 -2.4.2.28 deoxyadenosine trypanosoma brucei 9.6 9.6 1 PMID:27036940 -2.4.2.28 guanosine pyrococcus furiosus 7.31 7.31 1 PMID:12664268 -2.4.2.28 guanosine saccharolobus solfataricus 29.6 29.6 1 PMID:15819883 -2.4.2.28 inosine pyrococcus furiosus 9.38 9.38 1 PMID:12664268 -2.4.2.28 inosine saccharolobus solfataricus 132.0 132.0 1 PMID:15819883 -2.4.2.28 phosphate mycobacterium tuberculosis 0.26 0.26 1 PMID:22225784 -2.4.2.28 s-methyl-5'-thioadenosine brucella melitensis 8.8 8.8 1 PMID:24657441 -2.4.2.28 s-methyl-5'-thioadenosine trypanosoma brucei 2.13 2.13 1 PMID:27036940 -2.4.2.29 2-amino-5-(fluoromethyl)pyrrolo[2,3-d]pyrimidin-4(3h)-one escherichia coli 0.461 0.461 1 PMID:7492556 -2.4.2.29 [rnaecyma]-2'-deoxyguanine 34 escherichia coli 0.011 0.011 1 PMID:19874048 -2.4.2.29 [rnaecyma]-guanine escherichia coli 0.0094 0.0094 1 PMID:19874048 -2.4.2.29 [trna]-guanine zymomonas mobilis 0.014 0.014 1 PMID:19894214 -2.4.2.29 [trnatyr]7-aminomethyl-7-carbaguanine zymomonas mobilis 0.011 0.011 1 PMID:19627989 -2.4.2.29 guanine escherichia coli 7.57 4.390000000000001 2 PMID:11714265 -2.4.2.29 guanine zymomonas mobilis 0.056 0.0335 2 PMID:17949745;PMID:19894214 -2.4.2.29 guanine34 in trna escherichia coli 0.004 0.004 1 PMID:17626052 -2.4.2.29 pre-queuine 0 zymomonas mobilis 0.012 0.012 1 PMID:17949745 -2.4.2.29 pre-queuine 1 zymomonas mobilis 0.102 0.102 1 PMID:17949745 -2.4.2.29 trna escherichia coli 5.85 3.53 2 PMID:11714265 -2.4.2.29 trna guanine zymomonas mobilis 0.054 0.054 1 PMID:17949745 -2.4.2.29 virf minihelix rna escherichia coli 0.00033 0.00033 1 PMID:17626052 -2.4.2.29 virf mrna escherichia coli 0.00011 0.00011 1 PMID:17626052 -2.4.2.3 5-methyluridine aeropyrum pernix 56.0 56.0 1 PMID:23160980 -2.4.2.3 phosphate shewanella oneidensis 330.0 330.0 1 PMID:38723939 -2.4.2.3 thymidine schistosoma mansoni 0.41 0.41 1 PMID:26898674 -2.4.2.3 uridine aeropyrum pernix 150.0 150.0 1 PMID:23160980 -2.4.2.3 uridine phytophthora capsici 1188.0 1085.0 2 PMID:32493959 -2.4.2.3 uridine schistosoma mansoni 35.9 35.9 1 PMID:26898674 -2.4.2.30 (adp-d-ribosyl)n-actin aeromonas hydrophila 22.0 22.0 1 PMID:22969084 -2.4.2.30 (adp-d-ribosyl)n-soybean-trypsin-inhibitor pseudomonas aeruginosa 0.008 0.00555 2 PMID:7622246 -2.4.2.30 nad+ aeromonas hydrophila 22.0 22.0 1 PMID:22969084 -2.4.2.30 nad+ rattus norvegicus 12.0 12.0 1 PMID:12939142 -2.4.2.30 nad+ saccharolobus solfataricus 0.04 0.04 1 PMID:9761745 -2.4.2.30 nad+ streptomyces scabiei 1.57 1.57 1 PMID:27002155 -2.4.2.31 nad+ clostridium perfringens 0.01 0.0081 2 PMID:12791397 -2.4.2.31 nad+ homo sapiens 10.0 9.3 4 PMID:40273333 -2.4.2.31 nad+ lysinibacillus sphaericus 10.6 8.4 2 PMID:15379541 -2.4.2.31 protein l-arginine homo sapiens 10.0 10.0 1 PMID:40273333 -2.4.2.31 protein l-arginine methyl ester homo sapiens 8.0 8.0 1 PMID:40273333 -2.4.2.31 protein nalpha-acetyl-l-arginine homo sapiens 9.6 9.6 1 PMID:40273333 -2.4.2.31 protein nalpha-acetyl-l-arginine methyl ester homo sapiens 9.0 9.0 1 PMID:40273333 -2.4.2.36 elongation factor 2 pseudomonas aeruginosa 12.0 12.0 1 PMID:14705944 -2.4.2.36 nad+ pseudomonas aeruginosa 11.0 11.0 1 PMID:14705944 -2.4.2.37 nad+ azospirillum brasilense 0.501 0.501 1 PMID:23144248 -2.4.2.4 1-(2',6'-dideoxy-alpha-l-lyxo-hexafuranosyl)thymine escherichia coli 0.45 0.45 1 PMID:17309433 -2.4.2.4 1-(2',6'-dideoxy-alpha-l-lyxohexafuranosyl)thymine escherichia coli 0.45 0.45 1 PMID:17309433 -2.4.2.4 1-(2',6'-dideoxy-beta-d-ribo-hexafuranosyl)thymine escherichia coli 0.1 0.1 1 PMID:17309433 -2.4.2.4 1-(2',6'-dideoxy-beta-d-ribohexafuranosyl)thymine escherichia coli 0.6 0.6 3 PMID:17309433 -2.4.2.4 2'-deoxyuridine escherichia coli 35.0 35.0 1 PMID:17309433 -2.4.2.4 3'-amino-3'-deoxythymidine escherichia coli 1.1 1.1 2 PMID:17309433 -2.4.2.4 3'-deoxy-2',3'-didehydrothymidine escherichia coli 0.4 0.4 2 PMID:17309433 -2.4.2.4 4-thiothymidine escherichia coli 63.0 63.0 3 PMID:17309433 -2.4.2.4 5'-amino-5'-deoxythymidine escherichia coli 0.58 0.58 2 PMID:17309433 -2.4.2.4 5'-chloro-5'-deoxythymidine escherichia coli 1.7 1.7 1 PMID:17309433 -2.4.2.4 5'-deoxythymidine escherichia coli 260.0 260.0 2 PMID:17309433 -2.4.2.4 5-nitro-2'-deoxyuridine escherichia coli 20.0 20.0 2 PMID:15658853;PMID:17870212 -2.4.2.4 5-nitro-2'-deoxyuridine homo sapiens 2.88 2.88 1 PMID:15658853 -2.4.2.4 thymidine escherichia coli 1770.0 198.0 5 PMID:15658853;PMID:17309433;PMID:26752208 -2.4.2.4 thymidine homo sapiens 8.2 7.2 3 PMID:19555658;PMID:24407036;PMID:8444155 -2.4.2.44 5'-methylthioinosine pseudomonas aeruginosa 4.8 4.8 1 PMID:21197954 -2.4.2.44 adenine pseudomonas aeruginosa 0.0549 0.0549 1 PMID:21197954 -2.4.2.44 adenosine pseudomonas aeruginosa 0.0549 0.0549 1 PMID:21197954 -2.4.2.44 inosine pseudomonas aeruginosa 0.57 0.57 1 PMID:21197954 -2.4.2.44 s-methyl-5'-thioinosine pseudomonas aeruginosa 4.8 4.8 1 PMID:21197954 -2.4.2.48 guanine15 in trna methanosarcina acetivorans 0.0667 0.0489 2 PMID:23201278 -2.4.2.54 5-phospho-alpha-d-ribose 1-diphosphate methanocaldococcus jannaschii 0.23 0.23 1 PMID:15262968 -2.4.2.57 cmp thermococcus kodakarensis 39.1 39.1 1 PMID:23065974 -2.4.2.57 gmp thermococcus kodakarensis 2.7 2.7 1 PMID:23065974 -2.4.2.57 phosphate thermococcus kodakarensis 15.0 15.0 2 PMID:23065974 -2.4.2.57 ump thermococcus kodakarensis 10.5 10.5 1 PMID:23065974 -2.4.2.6 2',3'-dideoxycytidine limosilactobacillus fermentum 0.047 0.047 1 PMID:18487606 -2.4.2.6 2'-deoxycytidine lactobacillus leichmannii 62.2 62.2 1 PMID:18487606 -2.4.2.6 2'-deoxycytidine limosilactobacillus fermentum 45.1 45.1 1 PMID:18487606 -2.4.2.6 2'-deoxyinosine trypanosoma brucei brucei 7.9 7.15 2 * -2.4.2.6 2'-deoxyuridine limosilactobacillus reuteri 483.0 483.0 1 PMID:20048065 -2.4.2.6 2'-fluoro-2'-deoxyuridine lactobacillus leichmannii 0.000275 0.000275 1 PMID:35791073 -2.4.2.6 adenine trypanosoma brucei brucei 10.2 10.2 1 * -2.4.2.6 cytosine limosilactobacillus reuteri 2083.0 2083.0 1 PMID:20048065 -2.4.2.6 damp rattus norvegicus 0.0066 0.0066 1 PMID:17234634 -2.4.2.6 dcmp rattus norvegicus 0.0231 0.0231 1 PMID:17234634 -2.4.2.6 dgmp rattus norvegicus 0.0297 0.0297 1 PMID:17234634 -2.4.2.6 dimp rattus norvegicus 0.0066 0.0066 1 PMID:17234634 -2.4.2.6 dump rattus norvegicus 0.158 0.158 1 PMID:17234634 -2.4.2.64 7-aminomethyl-7-carbaguanine homo sapiens 0.00823 0.00823 1 PMID:21131277 -2.4.2.64 guanine escherichia coli 0.00629 0.00629 1 PMID:21640076 -2.4.2.64 guanine zymomonas mobilis 0.011 0.011 1 PMID:14523925 -2.4.2.64 guanine34 in trna zymomonas mobilis 0.014 0.014 1 PMID:14523925 -2.4.2.64 guanine34 in trnaasp homo sapiens 0.028 0.028 1 PMID:38181786 -2.4.2.64 hypoxanthine escherichia coli 0.00297 0.00297 1 PMID:16401090 -2.4.2.64 queuine homo sapiens 0.00822 0.00811 2 PMID:21131277;PMID:21640076 -2.4.2.64 queuine mus musculus 0.003 0.003 1 PMID:29862811 -2.4.2.64 xanthine escherichia coli 6.9e-05 6.9e-05 1 PMID:16401090 -2.4.2.7 5-phospho-alpha-d-ribose 1-diphosphate giardia duodenalis 2.8 2.8 1 PMID:12171924 -2.4.2.7 5-phospho-alpha-d-ribose 1-diphosphate homo sapiens 3.85 3.85 1 PMID:29576532 -2.4.2.7 5-phospho-alpha-d-ribose 1-diphosphate leishmania donovani 17.9 17.9 1 PMID:11900545 -2.4.2.7 5-phospho-alpha-d-ribose 1-diphosphate saccharolobus solfataricus 7.2 6.1 2 PMID:25790177 -2.4.2.7 5-phospho-alpha-d-ribose 1-diphosphate schistosoma mansoni 0.63 0.63 1 PMID:28392476 -2.4.2.7 5-phospho-alpha-d-ribose 1-diphosphate trypanosoma brucei brucei 1.8 1.74 3 PMID:34172767;PMID:35104286 -2.4.2.7 adenine escherichia coli 9.33 9.33 1 PMID:357906 -2.4.2.7 adenine giardia duodenalis 2.8 2.8 1 PMID:12171924 -2.4.2.7 adenine homo sapiens 3.85 2.055 2 PMID:29576532 -2.4.2.7 adenine saccharolobus solfataricus 5.4 5.35 2 PMID:25790177 -2.4.2.7 adenine schistosoma mansoni 0.47 0.47 1 PMID:28392476 -2.4.2.7 adenine trypanosoma brucei brucei 0.82 0.82 1 PMID:34172767 -2.4.2.7 amp giardia duodenalis 0.0095 0.0095 1 PMID:12171924 -2.4.2.7 diphosphate giardia duodenalis 0.0095 0.0095 1 PMID:12171924 -2.4.2.7 diphosphate leishmania donovani 11.3 11.3 1 PMID:11900545 -2.4.2.8 5-phospho-alpha-d-ribose 1-diphosphate caldanaerobacter subterraneus subsp. tengcongensis 4.26 4.26 1 PMID:15854655 -2.4.2.8 5-phospho-alpha-d-ribose 1-diphosphate giardia duodenalis 74.8 74.8 1 PMID:10092838 -2.4.2.8 5-phospho-alpha-d-ribose 1-diphosphate homo sapiens 2.5 2.5 1 PMID:18600559 -2.4.2.8 5-phospho-alpha-d-ribose 1-diphosphate leishmania donovani 36.3 36.3 1 PMID:9083019 -2.4.2.8 5-phospho-alpha-d-ribose 1-diphosphate mycobacterium tuberculosis 0.97 0.49195 2 PMID:19362594 -2.4.2.8 5-phospho-alpha-d-ribose 1-diphosphate plasmodium falciparum 1.6 0.2 16 PMID:25824378;PMID:26902413;PMID:27479359 -2.4.2.8 5-phospho-alpha-d-ribose 1-diphosphate pyrococcus horikoshii 3.05 1.17 4 PMID:18405676 -2.4.2.8 5-phospho-alpha-d-ribose 1-diphosphate thermus thermophilus 6.0 6.0 1 PMID:30643587 -2.4.2.8 5-phospho-alpha-d-ribose 1-diphosphate trypanosoma cruzi 32.2 23.2 4 PMID:11476964;PMID:15158715;PMID:15210120 -2.4.2.8 6-chloroguanine plasmodium falciparum 1.2 1.2 1 PMID:37220241 -2.4.2.8 6-mercaptopurine helicobacter pylori 2.4 2.4 1 PMID:33891818 -2.4.2.8 6-mercaptopurine plasmodium falciparum 0.4 0.4 1 PMID:37220241 -2.4.2.8 6-thioguanine helicobacter pylori 8.8 8.8 1 PMID:33891818 -2.4.2.8 6-thioguanine plasmodium falciparum 0.9 0.9 1 PMID:37220241 -2.4.2.8 6-thioxanthine helicobacter pylori 1.1 1.1 1 PMID:33891818 -2.4.2.8 6-thioxanthine plasmodium falciparum 0.4 0.4 1 PMID:37220241 -2.4.2.8 8-azaguanine plasmodium falciparum 4.9 4.9 1 PMID:37220241 -2.4.2.8 8-azahypoxanthine plasmodium falciparum 9.6 9.6 1 PMID:37220241 -2.4.2.8 allopurinol plasmodium falciparum 0.6 0.6 1 PMID:37220241 -2.4.2.8 diphosphate homo sapiens 0.041 0.041 1 PMID:18600559 -2.4.2.8 diphosphate leishmania donovani 90.0 90.0 1 PMID:9083019 -2.4.2.8 diphosphate trypanosoma cruzi 0.48 0.4735 4 PMID:11476964;PMID:15158715;PMID:15210120 -2.4.2.8 gmp giardia duodenalis 5.8 5.8 1 PMID:10092838 -2.4.2.8 gmp trypanosoma cruzi 0.09 0.09 1 PMID:15210120 -2.4.2.8 guanine caldanaerobacter subterraneus subsp. tengcongensis 0.0033 0.0027 3 PMID:14965769 -2.4.2.8 guanine giardia duodenalis 76.7 41.2 2 PMID:10092838 -2.4.2.8 guanine helicobacter pylori 7.3 7.3 1 PMID:33891818 -2.4.2.8 guanine homo sapiens 25.5 5.85 4 PMID:10833458;PMID:15178494;PMID:18536021 -2.4.2.8 guanine leishmania donovani 41.3 26.7 2 PMID:9083019;PMID:9430693 -2.4.2.8 guanine mycobacterium tuberculosis 0.193 0.1665 2 PMID:19362594 -2.4.2.8 guanine plasmodium falciparum 25.5 0.35 8 PMID:10833458;PMID:15178494;PMID:18536021;PMID:25824378;PMID:37220241 -2.4.2.8 guanine pyrococcus horikoshii 1.43 0.82 2 PMID:18405676 -2.4.2.8 guanine schistosoma mansoni 5.0 4.65 2 PMID:2199439 -2.4.2.8 guanine thermus thermophilus 20.0 11.0 2 PMID:20693661;PMID:30643587 -2.4.2.8 guanine trypanosoma brucei brucei 23.8 23.8 1 PMID:27786284 -2.4.2.8 guanine trypanosoma cruzi 32.9 32.9 3 PMID:11476964;PMID:15158715;PMID:15210120 -2.4.2.8 hypoxanthine caldanaerobacter subterraneus subsp. tengcongensis 15.9 7.97 3 PMID:14965769 -2.4.2.8 hypoxanthine helicobacter pylori 4.5 4.5 1 PMID:33891818 -2.4.2.8 hypoxanthine homo sapiens 9.3 4.15 6 PMID:10833458;PMID:15178494;PMID:18536021;PMID:18600559;PMID:9132023;PMID:9430693 -2.4.2.8 hypoxanthine leishmania donovani 8.54 7.119999999999999 2 PMID:10833458;PMID:9083019;PMID:9430693 -2.4.2.8 hypoxanthine mycobacterium tuberculosis 0.9 0.895 2 PMID:19362594 -2.4.2.8 hypoxanthine plasmodium falciparum 7.1 0.3 8 PMID:10833458;PMID:15178494;PMID:18536021;PMID:25824378;PMID:37220241 -2.4.2.8 hypoxanthine pyrococcus horikoshii 3.16 1.105 4 PMID:18405676 -2.4.2.8 hypoxanthine schistosoma mansoni 2.6 2.5 2 PMID:2199439 -2.4.2.8 hypoxanthine thermus thermophilus 9.1 9.05 2 PMID:20693661;PMID:30643587 -2.4.2.8 hypoxanthine trypanosoma brucei brucei 17.1 17.1 1 PMID:27786284 -2.4.2.8 hypoxanthine trypanosoma cruzi 22.9 22.9 3 PMID:11476964;PMID:15158715;PMID:15210120 -2.4.2.8 imp homo sapiens 0.038 0.038 1 PMID:18600559 -2.4.2.8 imp plasmodium falciparum 0.0042 0.0039 2 PMID:26902413 -2.4.2.8 imp trypanosoma cruzi 0.47 0.46499999999999997 2 PMID:15158715;PMID:15210120 -2.4.2.8 inosine monophosphate homo sapiens 0.3 0.3 1 PMID:9132023 -2.4.2.8 inosine monophosphate leishmania donovani 77.0 77.0 1 PMID:9083019 -2.4.2.8 inosine monophosphate trypanosoma cruzi 0.472 0.472 1 PMID:11476964 -2.4.2.8 xanthine helicobacter pylori 2.3 2.3 1 PMID:33891818 -2.4.2.8 xanthine homo sapiens 2.9 1.4809999999999999 2 PMID:10833458;PMID:18536021 -2.4.2.8 xanthine plasmodium falciparum 3.3 0.8 9 PMID:10833458;PMID:15178494;PMID:25824378;PMID:26902413;PMID:37220241 -2.4.2.8 xanthine pyrococcus horikoshii 2.2 1.4400000000000002 2 PMID:18405676 -2.4.2.9 5-phospho-alpha-d-ribose 1-diphosphate saccharolobus solfataricus 6.1 3.23 2 PMID:15752360 -2.4.2.9 ump bacillus subtilis 0.0015 0.0015 1 PMID:12482852 -2.4.2.9 uracil bacillus subtilis 5.1 5.1 1 PMID:12482852 -2.4.2.9 uracil mycobacterium tuberculosis 0.65 0.65 1 PMID:23424660 -2.4.2.9 uracil saccharolobus solfataricus 6.1 3.23 2 PMID:15752360 -2.4.3.1 4-methylumbelliferyl beta-d-lactoside photobacterium damselae 2.3 1.7 2 PMID:17989925 -2.4.3.1 5-(5-dimethylaminonaphthalene-1-sulfonyl-2-(2-aminoethoxy))ethyl beta-lactose rattus norvegicus 0.087 0.087 1 PMID:19500344 -2.4.3.1 5-(5-dimethylaminonaphthalene-1-sulfonyl-2-(2-aminoethoxy))ethyl beta-n-acetyllactosamine rattus norvegicus 1.13 1.13 1 PMID:19500344 -2.4.3.1 beta-d-galactosyl-(1->4)-n-acetyl-beta-d-glucosamine rattus norvegicus 0.67 0.51 2 PMID:24155237 -2.4.3.1 cmp-n-acetyl-beta-neuraminate homo sapiens 0.183 0.183 1 PMID:30706985 -2.4.3.1 cmp-n-acetylneuraminate photobacterium damselae 4.32 2.7 3 PMID:17989925;PMID:24142961 -2.4.3.1 cmp-n-acetylneuraminate rattus norvegicus 0.59 0.54 2 PMID:24155237 -2.4.3.1 cytidine-5'-yl-5-(acetamido)-9-(3-[4-chloro-1,2,3-oxadiazol-3-ium-5-olate]benzamido)-3,5,9-trideoxy-beta-d-glycero-d-galacto-non-2-ulopyranosid-2''-yl phosphate homo sapiens 0.0167 0.0167 1 PMID:30706985 -2.4.3.1 cytidine-5'-yl-5-(acetamido)-9-azido-3,5,9-trideoxy-beta-d-glycero-d-galacto-non-2-ulopyranosid-2''-yl phosphate homo sapiens 0.3 0.3 1 PMID:30706985 -2.4.3.1 lactose photobacterium damselae 4.3 4.3 1 PMID:24142961 -2.4.3.1 neu5acalpha-4-nitrophenyl photobacterium damselae 0.883 0.883 1 PMID:19880425 -2.4.3.3 cmp-n-acetyl-beta-neuraminate homo sapiens 0.183 0.183 1 PMID:30706985 -2.4.3.3 cytidine-5'-yl-5-(acetamido)-9-(3-[4-chloro-1,2,3-oxadiazol-3-ium-5-olate]benzamido)-3,5,9-trideoxy-beta-d-glycero-d-galacto-non-2-ulopyranosid-2''-yl phosphate homo sapiens 0.0167 0.0167 1 PMID:30706985 -2.4.3.3 cytidine-5'-yl-5-(acetamido)-9-azido-3,5,9-trideoxy-beta-d-glycero-d-galacto-non-2-ulopyranosid-2''-yl phosphate homo sapiens 0.3 0.3 1 PMID:30706985 -2.4.3.4 4-methylumbelliferyl 4-o-beta-d-galactosyl-beta-d-glucoside pasteurella multocida 47.0 47.0 1 PMID:21858283 -2.4.3.4 benzyl 2-acetamido-2-deoxy-3-o-(beta-d-galactopyranosyl)-alpha-d-galactopyranoside homo sapiens 3.15 3.15 1 PMID:31784620 -2.4.3.4 cmp-n-acetyl-beta-neuraminate homo sapiens 3.35 3.35 1 PMID:31784620 -2.4.3.4 cmp-n-acetylneuraminate pasteurella multocida 32.0 32.0 1 PMID:21858283 -2.4.3.6 4-methylumbelliferyl beta-lactoside pasteurella multocida 47.0 47.0 1 PMID:22583967 -2.4.3.6 4-methylumbelliferyl beta-lewis x pasteurella multocida 6.7 6.7 1 PMID:22583967 -2.4.3.6 cmp-n-acetyl-beta-neuraminate pasteurella multocida 32.0 27.0 3 PMID:22583967 -2.4.99.17 7-aminomethyl-7-deazaguanine in minihelix rna escherichia coli 0.245 0.245 1 PMID:12533518 -2.4.99.17 7-aminomethyl-7-deazaguanine in trna(tyr) escherichia coli 0.042 0.042 1 PMID:12533518 -2.4.99.17 s-adenosyl-l-methionine escherichia coli 0.042 0.042 1 PMID:12533518 -2.4.99.23 (3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->4)-(3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->6)-2-deoxy-2-[[(3r)-3-(dodecanoyloxy)tetradecanoyl]amino]-3-o-[(3r)-3-(tetradecanoyloxy)tetradecanoyl]-4-o-phospho-beta-d-glucopyranosyl-(1->6)-2-deoxy-3-o-[(3r)-3-hydroxytetradecanoyl]-2-[[(3r)-3-hydroxytetradecanoyl]amino]-1-o-phosphono-alpha-d-glucopyranose escherichia coli 6.6 5.65 2 PMID:22059588 -2.4.99.23 (3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->4)-(3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->6)-2-deoxy-2-[[(3r)-3-(dodecanoyloxy)tetradecanoyl]amino]-4-o-phospho-beta-d-glucopyranosyl-(1->6)-2-deoxy-2-[[(3r)-3-hydroxytetradecanoyl]amino]-1-o-phosphono-alpha-d-glucopyranose escherichia coli 1.47 1.2650000000000001 2 PMID:22059588 -2.4.99.23 (3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->4)-(3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->6)-2-deoxy-2-amino-4-o-phospho-beta-d-glucopyranosyl-(1->6)-2-deoxy-2-amino-1-o-phosphono-alpha-d-glucopyranose escherichia coli 1.05 0.905 2 PMID:22059588 -2.4.99.23 (3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->6)-2-deoxy-2-[[(3r)-3-(dodecanoyloxy)tetradecanoyl]amino]-3-o-[(3r)-3-(tetradecanoyloxy)tetradecanoyl]-4-o-phospho-beta-d-glucopyranosyl-(1->6)-2-deoxy-3-o-[(3r)-3-hydroxytetradecanoyl]-2-[[(3r)-3-(tetradecanoyloxy)tetradecanoyl]amino]-1-o-phosphono-alpha-d-glucopyranose escherichia coli 8.0 4.53 2 PMID:22059588 -2.4.99.23 adp-l-glycero-beta-d-manno-heptose escherichia coli 0.36 0.36 1 PMID:35508636 -2.4.99.23 alpha-kdo-(2->4)-alpha-kdo-(2->6)-[o-deacylated escherichia coli kdo2-lipid a] escherichia coli 0.36 0.36 1 PMID:32011131 -2.4.99.25 alpha-l-glycero-d-manno-heptosyl-(1->3)-((4-o-phospho)-alpha-l-glycero-d-manno-heptosyl-(1->5))-[(3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->4)]-(3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->6)-2-deoxy-2-[[(3r)-3-(hydroxy)tetradecanoyl]amino]-4-o-phospho-beta-d-glucopyranosyl-(1->6)-2-deoxy-2-[[(3r)-3-hydroxytetradecanoyl]amino]-1-o-phosphono-alpha-d-glucopyranose escherichia coli 0.028 0.0235 2 PMID:25957775 -2.4.99.25 alpha-l-glycero-d-manno-heptosyl-(1->3)-((4-o-phospho)-alpha-l-glycero-d-manno-heptosyl-(1->5))-[(3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->4)]-(3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->6)-2-deoxy-2-amino-4-o-phospho-beta-d-glucopyranosyl-(1->6)-2-deoxy-2-amino-1-o-phosphono-alpha-d-glucopyranose escherichia coli 0.07 0.07 1 PMID:25957775 -2.4.99.25 alpha-l-glycero-d-manno-heptosyl-(1->3)-((4-o-phospho)-alpha-l-glycero-d-manno-heptosyl-(1->5))-[(3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->4)]-(3-deoxy-alpha-d-manno-oct-2-ulopyranosylonate)-(2->6)-2-deoxy-3-o-[(3r)-3-(tetradecanoyloxy)tetradecanoyl]-2-[[(3r)-3-(dodecanoyloxy)tetradecanoyl]amino]-4-o-phospho-beta-d-glucopyranosyl-(1->6)-2-deoxy-3-o-[(3r)-3-hydroxytetradecanoyl]-2-[[(3r)-3-hydroxytetradecanoyl]amino]-1-o-phosphono-alpha-d-glucopyranose escherichia coli 0.041 0.02295 2 PMID:25957775 -2.4.99.28 [glcnac-(1-4)-mur2ac(oyl-l-ala-gamma-d-glu-(l)-meso-diaminopimelic acid-(l)-d-ala-d-ala)]n-diphosphoundecaprenol escherichia coli 70.0 70.0 1 PMID:18701463 -2.4.99.28 [glcnac-(1-4)-mur2ac(oyl-l-ala-gamma-d-glu-l-lys-d-ala-d-ala)]n-diphosphoundecaprenol escherichia coli 3.14 3.14 1 PMID:19458048 -2.4.99.28 d-lactate escherichia coli 0.42 0.42 1 PMID:32048840 -2.4.99.28 l-alanine escherichia coli 1.13 1.13 1 PMID:32048840 -2.4.99.28 lipid i-meso-dap escherichia coli 0.7 0.7 1 PMID:32048840 -2.4.99.28 lipid ii-meso-dap escherichia coli 2.67 2.67 1 PMID:32048840 -2.4.99.28 lipid ii-meso-dap tetrapeptide escherichia coli 0.68 0.68 1 PMID:32048840 -2.4.99.28 murnac-meso-dap pentapeptide escherichia coli 1.83 1.83 1 PMID:32048840 -2.4.99.28 murnac-meso-dap pentapeptide-nh2 escherichia coli 1.45 1.45 1 PMID:32048840 -2.4.99.28 murnac-meso-dap tetrapeptide escherichia coli 0.81 0.81 1 PMID:32048840 -2.4.99.28 murnac-meso-dap tetrapeptide-nh2 escherichia coli 3.17 3.17 1 PMID:32048840 -2.4.99.28 murnac-meso-dap tripeptide escherichia coli 1.27 1.27 1 PMID:32048840 -2.4.99.28 murnac-meso-dap tripeptide-nh2 escherichia coli 1.8 1.8 1 PMID:32048840 -2.4.99.28 undecaprenyl-diphosphoryl-murnac-(l-ala-gamma-d-glu-meso-(diaminopimelic acid)-d-ala-d-ala)-glcnac staphylococcus aureus 0.013 0.0078 4 PMID:16547040 -2.5.1.1 dimethylallyl diphosphate corynebacterium glutamicum 1.1 1.1 1 PMID:25181035 -2.5.1.1 dimethylallyl diphosphate mycobacterium tuberculosis 0.085 0.085 1 PMID:21237161 -2.5.1.1 dimethylallyl diphosphate picea abies 1.4 1.4 1 PMID:19939949 -2.5.1.1 farnesyl diphosphate corynebacterium glutamicum 0.4 0.4 1 PMID:25181035 -2.5.1.1 geranyl diphosphate corynebacterium glutamicum 0.1 0.1 1 PMID:25181035 -2.5.1.1 isopentenyl diphosphate corynebacterium glutamicum 1.1 1.1 1 PMID:25181035 -2.5.1.1 isopentenyl diphosphate mycobacterium tuberculosis 0.012 0.012 1 PMID:21237161 -2.5.1.10 dimethylallyl diphosphate sundstroemia setigera 5.73 5.73 1 PMID:25996801 -2.5.1.10 geranyl diphosphate mycobacterium tuberculosis 0.2 0.2 1 PMID:15060088 -2.5.1.10 geranyl diphosphate sundstroemia setigera 43.5 43.5 1 PMID:25996801 -2.5.1.10 isopentenyl diphosphate mycobacterium tuberculosis 0.49 0.49 1 PMID:15060088 -2.5.1.10 isopentenyl diphosphate sundstroemia setigera 33.5 19.75 2 PMID:25996801 -2.5.1.100 dimethylallyl diphosphate aspergillus fumigatus 0.8 0.8 1 PMID:16397874 -2.5.1.100 fumigaclavine a aspergillus fumigatus 0.8 0.8 1 PMID:16397874 -2.5.1.104 agmatine pyrococcus furiosus 0.1 0.1 1 PMID:17545282 -2.5.1.104 agmatine thermococcus kodakarensis 0.28 0.28 1 PMID:20675472 -2.5.1.104 agmatine thermus thermophilus 0.37 0.37 1 PMID:15983049;PMID:21458463 -2.5.1.104 cadaverine pyrococcus furiosus 2.09 2.09 1 PMID:17545282 -2.5.1.104 cadaverine thermococcus kodakarensis 0.02 0.02 1 PMID:20675472 -2.5.1.104 norspermidine thermus thermophilus 0.53 0.53 1 PMID:21458463 -2.5.1.104 propane-1,3-diamine pyrococcus furiosus 0.06 0.06 1 PMID:17545282 -2.5.1.104 putrescine pyrococcus furiosus 0.18 0.18 1 PMID:17545282 -2.5.1.104 putrescine thermococcus kodakarensis 0.3 0.3 1 PMID:20675472 -2.5.1.104 s-adenosyl 3-(methylthio)propylamine thermus thermophilus 0.73 0.73 1 PMID:21458463 -2.5.1.104 spermidine thermus thermophilus 0.65 0.65 1 PMID:21458463 -2.5.1.104 tris(3-aminopropyl)amine thermus thermophilus 0.29 0.29 1 PMID:21458463 -2.5.1.106 (e)-4-(1h-indol-3-yl)but-3-en-2-one aspergillus fumigatus 0.4 0.4 1 PMID:22642693 -2.5.1.106 brevianamide f aspergillus fumigatus 5.57 4.8100000000000005 2 PMID:16000710;PMID:23090579 -2.5.1.106 cyclo-(d-trp-d-pro) aspergillus fumigatus 0.31 0.31 1 PMID:23090579 -2.5.1.106 cyclo-(d-trp-l-ala) aspergillus fumigatus 0.24 0.15 2 PMID:23090579 -2.5.1.106 cyclo-(l-trp-d-ala) aspergillus fumigatus 0.71 0.71 1 PMID:23090579 -2.5.1.106 cyclo-(l-trp-gly) aspergillus fumigatus 3.14 2.8449999999999998 2 PMID:23090579 -2.5.1.106 cyclo-(l-trp-l-ala) aspergillus fumigatus 1.47 0.8 2 PMID:23090579 -2.5.1.106 cyclo-(l-trp-l-his) aspergillus fumigatus 21.14 21.14 1 PMID:23090579 -2.5.1.106 cyclo-(l-trp-l-pro) aspergillus fumigatus 8.9 8.9 1 PMID:27311563 -2.5.1.106 cyclo-(l-trp-l-tyr) aspergillus fumigatus 1.73 0.91 2 PMID:23090579 -2.5.1.109 (s)-benzodiazepinedione aspergillus terreus 0.125 0.125 1 PMID:25125042 -2.5.1.109 brevianamide f aspergillus sp. 0.32 0.32 1 PMID:20722388 -2.5.1.109 brevianamide f aspergillus versicolor 0.276 0.276 2 PMID:22660767 -2.5.1.109 cyclo-d-trp-d-ala aspergillus versicolor 0.011 0.011 2 PMID:22660767 -2.5.1.109 cyclo-d-trp-d-pro aspergillus versicolor 0.095 0.095 2 PMID:22660767 -2.5.1.109 cyclo-d-trp-l-ala aspergillus versicolor 0.003 0.003 2 PMID:22660767 -2.5.1.109 cyclo-d-trp-l-pro aspergillus versicolor 0.027 0.027 2 PMID:22660767 -2.5.1.109 cyclo-l-trp-d-ala aspergillus versicolor 0.013 0.013 2 PMID:22660767 -2.5.1.109 cyclo-l-trp-d-pro aspergillus versicolor 0.15 0.15 2 PMID:22660767 -2.5.1.109 cyclo-l-trp-gly aspergillus versicolor 0.032 0.032 2 PMID:22660767 -2.5.1.109 cyclo-l-trp-l-ala aspergillus versicolor 0.035 0.035 2 PMID:22660767 -2.5.1.109 cyclo-l-trp-l-leu aspergillus versicolor 0.014 0.014 2 PMID:22660767 -2.5.1.109 cyclo-l-trp-l-phe aspergillus versicolor 0.004 0.004 2 PMID:22660767 -2.5.1.109 cyclo-l-trp-l-tyr aspergillus versicolor 0.006 0.006 2 PMID:22660767 -2.5.1.109 cyclo-l-tyr-l-tyr aspergillus terreus 0.012 0.012 1 PMID:25125042 -2.5.1.109 dimethylallyl diphosphate aspergillus sp. 0.42 0.42 1 PMID:20722388 -2.5.1.109 dimethylallyl diphosphate aspergillus terreus 0.067 0.067 1 PMID:25125042 -2.5.1.109 dimethylallyl diphosphate aspergillus versicolor 0.49 0.4895 2 PMID:22660767 -2.5.1.110 12alpha,13alpha-dihydroxyfumitremorgin c aspergillus fumigatus 0.03 0.03 1 PMID:18683158 -2.5.1.110 dimethylallyl diphosphate aspergillus fumigatus 0.03 0.03 1 PMID:18683158 -2.5.1.111 4-hydroxyphenylpyruvate streptomyces niveus 0.083 0.083 1 PMID:19557032 -2.5.1.111 4-hydroxyphenylpyruvate streptomyces roseochromogenus subsp. oscitans 0.159 0.159 1 PMID:20946900 -2.5.1.111 dimethylallyl diphosphate streptomyces niveus 0.083 0.083 1 PMID:19557032 -2.5.1.111 dimethylallyl diphosphate streptomyces roseochromogenus subsp. oscitans 0.253 0.253 1 PMID:20946900 -2.5.1.111 menadione hydroquinol streptomyces niveus 0.038 0.038 1 PMID:32125480 -2.5.1.112 adp humulus lupulus 0.024 0.024 1 PMID:15381407 -2.5.1.112 adp morus alba 0.024 0.024 1 PMID:17320045 -2.5.1.112 amp humulus lupulus 0.008 0.008 1 PMID:15381407 -2.5.1.112 atp humulus lupulus 0.022 0.022 1 PMID:15381407 -2.5.1.112 dimethylallyl diphosphate humulus lupulus 0.027 0.027 1 PMID:15381407 -2.5.1.112 dimethylallyl diphosphate morus alba 0.035 0.035 1 PMID:17320045 -2.5.1.113 o-phospho-l-serine mycobacterium tuberculosis 0.1 0.1 1 PMID:18799456 -2.5.1.120 3-[(1-carboxyvinyl)oxy]benzoate thermus thermophilus 0.0037 0.0037 1 PMID:28701039 -2.5.1.121 5,10-dihydrophenazine 1-carboxylate streptomyces anulatus 0.435 0.435 1 PMID:19339241 -2.5.1.122 (2e)-2-methylpenta-2,4-dien-1-yl diphosphate plenodomus lingam 0.00367 0.00367 1 PMID:28960770 -2.5.1.122 (2e)-3-methylpent-2-en-1-yl diphosphate plenodomus lingam 0.3 0.3 1 PMID:28960770 -2.5.1.122 (2e)-5-methylhexa-2,4-dien-1-yl diphosphate plenodomus lingam 0.00167 0.00167 1 PMID:28960770 -2.5.1.122 (2e)-but-2-en-1-yl diphosphate plenodomus lingam 0.001 0.001 1 PMID:28960770 -2.5.1.122 (2e)-penta-2,4-dien-1-yl diphosphate plenodomus lingam 0.00083 0.00083 1 PMID:28960770 -2.5.1.122 (2e,4z)-2-methylhexa-2,4-dien-1-yl diphosphate plenodomus lingam 0.0123 0.0123 1 PMID:28960770 -2.5.1.122 (2z)-3-chlorobut-2-en-1-yl diphosphate plenodomus lingam 0.00067 0.00067 1 PMID:28960770 -2.5.1.122 2-cyclohexylideneethyl diphosphate plenodomus lingam 0.0583 0.0583 1 PMID:28960770 -2.5.1.122 2-pentenyl diphosphate aspergillus niger 0.003 0.003 1 PMID:25707862 -2.5.1.122 2-pentenyl diphosphate plenodomus lingam 0.002 0.002 1 PMID:25707862 -2.5.1.122 3,4-dihydroxy-l-phenylalanine aspergillus niger 0.27 0.27 1 PMID:24970457 -2.5.1.122 3-ethylpent-2-en-1-yl diphosphate plenodomus lingam 0.055 0.055 1 PMID:28960770 -2.5.1.122 3-iodo-l-tyrosine aspergillus niger 0.16 0.16 1 PMID:24970457 -2.5.1.122 4-methyl-dl-tryptophan aspergillus niger 0.2 0.1018 2 PMID:24970457 -2.5.1.122 alpha-methyl-l-tyrosine aspergillus niger 0.26 0.26 1 PMID:24970457 -2.5.1.122 benzyl diphosphate aspergillus niger 0.016 0.016 1 PMID:25707862 -2.5.1.122 benzyl diphosphate plenodomus lingam 0.028 0.028 1 PMID:25707862 -2.5.1.122 cyclohex-1-en-1-ylmethyl diphosphate plenodomus lingam 0.0055 0.0055 1 PMID:28960770 -2.5.1.122 d-tyrosine aspergillus niger 0.16 0.16 1 PMID:24970457 -2.5.1.122 dimethylallyl diphosphate aspergillus niger 0.69 0.69 2 PMID:24970457;PMID:25707862 -2.5.1.122 dimethylallyl diphosphate plenodomus lingam 1.0 0.8415 2 PMID:25707862;PMID:28960770 -2.5.1.122 l-o-tyrosine aspergillus niger 0.014 0.014 1 PMID:26077893 -2.5.1.122 l-tryptophan aspergillus niger 0.0053 0.0053 1 PMID:24970457 -2.5.1.122 l-tryptophan plenodomus lingam 0.095 0.095 1 PMID:24083562 -2.5.1.122 l-tyrosine aspergillus niger 0.58 0.58 2 PMID:24970457 -2.5.1.122 l-tyrosine plenodomus lingam 1.3 1.15 2 PMID:19762440;PMID:24083562 -2.5.1.122 methylallyl diphosphate aspergillus niger 0.002 0.002 1 PMID:25707862 -2.5.1.122 methylallyl diphosphate plenodomus lingam 0.003 0.003 1 PMID:25707862 -2.5.1.123 1,3-dihydroxynaphthalene streptomyces virginiae 0.003 0.003 1 PMID:17543953 -2.5.1.123 4-hydroxybenzoate streptomyces virginiae 0.002 0.002 1 PMID:17543953 -2.5.1.123 flaviolin streptomyces virginiae 0.0002 0.0002 1 PMID:17543953 -2.5.1.124 1,3-dihydroxynaphthalene streptomyces sp. 0.00013 0.00013 1 PMID:20937800 -2.5.1.124 2-o-methyl-3-methylflaviolin streptomyces sp. 0.00066 0.00066 1 PMID:20937800 -2.5.1.124 flaviolin streptomyces sp. 0.028 0.014435 2 PMID:20937800 -2.5.1.125 1,3-dihydroxynaphthalene streptomyces sp. 0.00013 0.00013 1 PMID:20937800 -2.5.1.125 2-o-methyl-3-methylflaviolin streptomyces sp. 0.00066 0.00066 1 PMID:20937800 -2.5.1.125 flaviolin streptomyces sp. 0.028 0.014435 2 PMID:20937800 -2.5.1.132 d-mannose 6-phosphate bacteroides thetaiotaomicron 0.017 0.017 1 PMID:18804026 -2.5.1.132 d-mannose 6-phosphate homo sapiens 0.0011 0.0011 1 PMID:16503877 -2.5.1.132 phosphoenolpyruvate bacteroides thetaiotaomicron 0.017 0.017 1 PMID:18804026 -2.5.1.135 gdp-valienol streptomyces hygroscopicus subsp. limoneus 7.0 3.545 2 PMID:21766819;PMID:38130475 -2.5.1.135 validamine 7-phosphate streptomyces hygroscopicus subsp. limoneus 7.0 7.0 1 PMID:21766819 -2.5.1.136 2-methyl-1-(2,4,6-trihydroxyphenyl)propan-1-one aspergillus terreus 0.284 0.149 2 PMID:28029789 -2.5.1.136 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one aspergillus terreus 0.012 0.012 1 PMID:28029789 -2.5.1.136 dimethylallyl diphosphate aspergillus terreus 0.27 0.27 2 PMID:28029789 -2.5.1.136 geranyl diphosphate aspergillus terreus 0.126 0.126 2 PMID:28029789 -2.5.1.136 phenyl(2,4,6-trihydroxyphenyl)methanone aspergillus terreus 0.137 0.07450000000000001 2 PMID:28029789 -2.5.1.140 l-glutamate staphylococcus aureus 3.6 3.6 1 PMID:26794841 -2.5.1.140 o-phospho-l-serine staphylococcus aureus 2.3 2.3 1 PMID:26794841 -2.5.1.142 isopentenyl diphosphate solanum lycopersicum 0.0026 0.0026 1 PMID:25786135 -2.5.1.142 z,z-farnesyl diphosphate solanum lycopersicum 0.0026 0.0026 1 PMID:25786135 -2.5.1.148 (2e,6e)-farnesyl diphosphate botryococcus braunii 0.0205 0.0205 1 PMID:27050299 -2.5.1.148 geranylgeranyl diphosphate botryococcus braunii 0.0114 0.0114 1 PMID:27050299 -2.5.1.15 (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate plasmodium falciparum 0.069 0.069 1 PMID:19631695 -2.5.1.15 (7,8-dihydropterin-6-yl)methyl diphosphate plasmodium vivax 0.0024 0.0024 1 PMID:27161627 -2.5.1.15 4-aminobenzoate bacillus anthracis 0.109 0.109 1 PMID:18342015 -2.5.1.15 4-aminobenzoate plasmodium falciparum 0.015 0.015 1 PMID:31883412 -2.5.1.15 4-aminobenzoate plasmodium vivax 0.0024 0.0024 1 PMID:27161627 -2.5.1.15 dapson bacillus anthracis 0.0578 0.0578 1 PMID:18342015 -2.5.1.15 sulfadiazine bacillus anthracis 0.1243 0.1243 1 PMID:18342015 -2.5.1.15 sulfamethizole bacillus anthracis 0.079 0.079 1 PMID:18342015 -2.5.1.15 sulfamethoxazole bacillus anthracis 0.12 0.12 1 PMID:18342015 -2.5.1.15 sulfanilamide bacillus anthracis 0.08 0.08 1 PMID:18342015 -2.5.1.15 sulfathiazole bacillus anthracis 0.0887 0.0887 1 PMID:18342015 -2.5.1.15 sulfisoxazole bacillus anthracis 0.11 0.11 1 PMID:18342015 -2.5.1.151 5'-deoxyadenosylcobalamin homo sapiens 0.174 0.174 1 PMID:19801555 -2.5.1.151 butyrylcobalamin homo sapiens 0.036 0.036 1 PMID:19801555 -2.5.1.151 cyanocobalamin homo sapiens 0.0917 0.0917 1 PMID:32457044 -2.5.1.151 ethylcobalamin homo sapiens 1.86 1.86 1 PMID:19801555 -2.5.1.151 hexylcobalamin homo sapiens 0.022 0.022 1 PMID:19801555 -2.5.1.151 methylcobalamin homo sapiens 11.7 5.85135 2 PMID:19801555;PMID:32457044 -2.5.1.151 nitrocobalamin homo sapiens 0.027 0.027 1 PMID:32457044 -2.5.1.151 pentylcobalamin homo sapiens 0.024 0.024 1 PMID:19801555 -2.5.1.151 propylcobalamin homo sapiens 0.13 0.13 1 PMID:19801555 -2.5.1.152 d-histidine staphylococcus aureus 0.298 0.298 1 PMID:29091735 -2.5.1.153 tuberculosinyl diphosphate mycobacterium tuberculosis 0.000517 0.000517 1 PMID:21228491 -2.5.1.154 atp listeria monocytogenes serotype 1/2a 0.24 0.24 1 PMID:32125848 -2.5.1.154 cob(ii)alamin listeria monocytogenes serotype 1/2a 0.21 0.21 1 PMID:32125848 -2.5.1.159 hapalindole g fischerella ambigua 0.088 0.088 1 PMID:24180436 -2.5.1.16 putrescine homo sapiens 1.9 1.9 1 PMID:17585781 -2.5.1.16 putrescine thermotoga maritima 22.7 11.735 2 PMID:17585781 -2.5.1.16 s-adenosylmethioninamine escherichia coli 0.14 0.14 1 PMID:23001854 -2.5.1.16 s-adenosylmethioninamine homo sapiens 1.9 1.9 1 PMID:17585781 -2.5.1.16 s-adenosylmethioninamine thermotoga maritima 22.7 11.735 2 PMID:17585781 -2.5.1.160 o-phospho-l-homoserine arabidopsis thaliana 30.0 30.0 1 * -2.5.1.17 2'-deoxy-atp limosilactobacillus reuteri 0.0051 0.0051 1 PMID:17988155 -2.5.1.17 atp homo sapiens 297.6 285.0 3 PMID:18251506 -2.5.1.17 atp limosilactobacillus reuteri 0.029 0.026 3 PMID:17121823;PMID:19236001 -2.5.1.17 atp listeria monocytogenes 0.24 0.24 1 PMID:32125848 -2.5.1.17 atp salmonella enterica 0.08 0.03 3 PMID:16636051;PMID:23148601;PMID:25423616 -2.5.1.17 atp thermoplasma acidophilum 0.23 0.23 1 PMID:15044458 -2.5.1.17 cob(i)alamin homo sapiens 297.6 225.6 4 PMID:16439175;PMID:18251506 -2.5.1.17 cob(i)alamin limosilactobacillus reuteri 0.025 0.0245 2 PMID:17121823;PMID:19236001 -2.5.1.17 cob(i)alamin salmonella enterica 0.08 0.06 3 PMID:16636051;PMID:23148601;PMID:24336938 -2.5.1.17 cob(i)inamide limosilactobacillus reuteri 0.02 0.02 1 PMID:18672897 -2.5.1.17 cob(ii)alamin limosilactobacillus reuteri 0.038 0.038 1 PMID:19236001 -2.5.1.17 cob(ii)alamin listeria monocytogenes 0.21 0.21 1 PMID:32125848 -2.5.1.17 cob(ii)inamide salmonella enterica 0.0077 0.0077 1 PMID:25423616 -2.5.1.17 ctp limosilactobacillus reuteri 0.0086 0.0086 1 PMID:17988155 -2.5.1.17 datp thermoplasma acidophilum 0.11 0.11 1 PMID:15044458 -2.5.1.17 gtp limosilactobacillus reuteri 0.021 0.021 1 PMID:17988155 -2.5.1.17 hydroxocobalamin thermoplasma acidophilum 0.18 0.18 1 PMID:15044458 -2.5.1.17 itp limosilactobacillus reuteri 0.019 0.019 1 PMID:17988155 -2.5.1.17 utp limosilactobacillus reuteri 0.00195 0.00195 1 PMID:17988155 -2.5.1.18 (+)-2-bromo-3-(4-nitrophenyl)propanoic acid homo sapiens 13.0 0.705 4 PMID:12852784 -2.5.1.18 (r)-styrene-7,8-oxide homo sapiens 4.8 4.8 1 PMID:17689871 -2.5.1.18 (r,r)-1-phenylpropylene oxide homo sapiens 17.7 17.7 1 PMID:17689871 -2.5.1.18 (r,r)-trans-stilbene oxide homo sapiens 7.7 1.3 3 PMID:17689871 -2.5.1.18 (s)-styrene-7,8-oxide homo sapiens 8.4 8.4 1 PMID:17689871 -2.5.1.18 (s,s)-1-phenylpropylene oxide homo sapiens 9.0 2.4 3 PMID:17689871 -2.5.1.18 (s,s)-trans-stilbene oxide homo sapiens 0.46 0.2 3 PMID:17689871 -2.5.1.18 1,2-dichloro-4-nitrobenzene homo sapiens 210.0 210.0 1 * -2.5.1.18 1,2-epoxy-3-(p-nitrophenoxy)propane homo sapiens 201.0 201.0 1 * -2.5.1.18 1,3-bis-(2-chloroethyl)-1-nitrosourea homo sapiens 0.035 0.035 1 PMID:20211594 -2.5.1.18 1,3-bis-(2-chloroethyl)-1-nitrosourea mus musculus 2.3 2.3 1 PMID:20211594 -2.5.1.18 1-chloro-2,3-dinitrobenzene atactodea striata 772.0 772.0 1 PMID:12893269 -2.5.1.18 1-chloro-2,3-dinitrobenzene pinus tabuliformis 6.0 6.0 1 PMID:15820751 -2.5.1.18 1-chloro-2,4-dinitrobenzene aedes aegypti 51.0 17.0 8 PMID:21195177 -2.5.1.18 1-chloro-2,4-dinitrobenzene agrobacterium tumefaciens 0.53 0.53 1 PMID:22496785 -2.5.1.18 1-chloro-2,4-dinitrobenzene alternaria brassicicola 38.18 1.5 3 PMID:26081847 -2.5.1.18 1-chloro-2,4-dinitrobenzene anopheles dirus 26.5 25.65 4 PMID:12708968;PMID:15705499;PMID:16153184;PMID:18760991 -2.5.1.18 1-chloro-2,4-dinitrobenzene anopheles gambiae 0.098 0.098 1 PMID:18569345 -2.5.1.18 1-chloro-2,4-dinitrobenzene bombyx mori 65.43 65.43 1 * -2.5.1.18 1-chloro-2,4-dinitrobenzene bos taurus 190.6 190.6 1 PMID:18221006 -2.5.1.18 1-chloro-2,4-dinitrobenzene brucella anthropi 2.35 2.35 1 PMID:18076047 -2.5.1.18 1-chloro-2,4-dinitrobenzene camelus dromedarius 4.62 4.62 1 PMID:27639582 -2.5.1.18 1-chloro-2,4-dinitrobenzene cydia pomonella 610.0 610.0 1 PMID:25640718 -2.5.1.18 1-chloro-2,4-dinitrobenzene escherichia coli 9.1 9.1 1 PMID:18778244 -2.5.1.18 1-chloro-2,4-dinitrobenzene fasciola gigantica 87.87 73.32000000000001 2 PMID:29235505;PMID:32663558 -2.5.1.18 1-chloro-2,4-dinitrobenzene gelatoporia subvermispora 0.18 0.18 1 PMID:30928378 -2.5.1.18 1-chloro-2,4-dinitrobenzene glycine max 2.48 2.48 1 PMID:19879385 -2.5.1.18 1-chloro-2,4-dinitrobenzene homo sapiens 761.0 76.0 7 PMID:17046132;PMID:21728995;PMID:6517933;PMID:8663072;PMID:8663073 -2.5.1.18 1-chloro-2,4-dinitrobenzene macrobrachium vollenhovenii 20.3 20.3 1 PMID:15674845 -2.5.1.18 1-chloro-2,4-dinitrobenzene monopterus albus 2.44 2.44 1 * -2.5.1.18 1-chloro-2,4-dinitrobenzene mucor mucedo 552.0 295.9 2 PMID:16209109 -2.5.1.18 1-chloro-2,4-dinitrobenzene mus musculus 2286.0 2286.0 1 PMID:16507568 -2.5.1.18 1-chloro-2,4-dinitrobenzene musca domestica 25.1 18.4 2 PMID:23268341 -2.5.1.18 1-chloro-2,4-dinitrobenzene nilaparvata lugens 2.67 2.67 1 PMID:25497345 -2.5.1.18 1-chloro-2,4-dinitrobenzene pagrus major 3.56 3.56 1 PMID:15610066 -2.5.1.18 1-chloro-2,4-dinitrobenzene penaeus vannamei 251.2 126.175 2 PMID:17427177 -2.5.1.18 1-chloro-2,4-dinitrobenzene phanerodontia chrysosporium 2.08 2.08 1 PMID:23063695 -2.5.1.18 1-chloro-2,4-dinitrobenzene pinus tabuliformis 6.74 6.74 1 PMID:15862305 -2.5.1.18 1-chloro-2,4-dinitrobenzene populus trichocarpa 5.3 4.095 2 PMID:26026470 -2.5.1.18 1-chloro-2,4-dinitrobenzene proteus mirabilis 2.13 2.13 1 PMID:20663851 -2.5.1.18 1-chloro-2,4-dinitrobenzene rattus norvegicus 82.0 64.0 6 PMID:4025799 -2.5.1.18 1-chloro-2,4-dinitrobenzene salix babylonica 112.987 16.183 13 PMID:32308662 -2.5.1.18 1-chloro-2,4-dinitrobenzene sarcoptes scabiei 193.0 193.0 1 PMID:15619514 -2.5.1.18 1-chloro-2,4-dinitrobenzene schistosoma japonicum 187.0 187.0 1 PMID:17226963 -2.5.1.18 1-chloro-2,4-dinitrobenzene setaria cervi 1515.0 1515.0 1 PMID:17367761 -2.5.1.18 1-chloro-2,4-dinitrobenzene solenopsis invicta 74.5 74.5 1 PMID:14505691 -2.5.1.18 1-chloro-2,4-dinitrobenzene sus scrofa 99.0 91.5 2 PMID:21172301;PMID:25640718 -2.5.1.18 1-chloro-2,4-dinitrobenzene taenia crassiceps 62.5 32.245 2 PMID:29032785 -2.5.1.18 1-chloro-2,4-dinitrobenzene taenia solium 22.2 22.2 1 PMID:18662665 -2.5.1.18 1-chloro-2,4-dinitrobenzene tetranychus urticae 0.25 0.051 3 PMID:26047112 -2.5.1.18 1-chloro-2,4-dinitrobenzene trichinella spiralis 18.0 18.0 1 PMID:25758588 -2.5.1.18 1-chloro-2,4-dinitrobenzene triticum aestivum 10.9 10.9 1 PMID:25640718 -2.5.1.18 1-fluoro-2,4-dinitrobenzene homo sapiens 106.0 106.0 1 PMID:8663072 -2.5.1.18 1-fluoro-2,4-dinitrobenzene proteus mirabilis 6.78 6.78 1 PMID:20663851 -2.5.1.18 1-iodobutane mus musculus 0.137 0.137 1 PMID:20097269 -2.5.1.18 1-iodohexane callithrix jacchus 1.1 0.62 5 PMID:32027883 -2.5.1.18 1-iodohexane mus musculus 3.17 3.17 1 PMID:20097269 -2.5.1.18 1-iodomethane mus musculus 238.0 238.0 1 PMID:20097269 -2.5.1.18 2-chloro-5-nitropyridine schistosoma japonicum 0.044 0.044 1 PMID:17226963 -2.5.1.18 2-hydroxychromene-2-carboxylic acid pseudomonas putida 47.0 47.0 1 PMID:17508726 -2.5.1.18 2-hydroxyethyl disulfide agrobacterium tumefaciens 0.04 0.04 1 PMID:22496785 -2.5.1.18 3,4-dinitrobenzanilide homo sapiens 367.0 367.0 1 PMID:18841967 -2.5.1.18 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole oryza sativa 0.257 0.257 1 PMID:31878175 -2.5.1.18 4-hydroxy-(e)-2-nonenal spinacia oleracea 0.262 0.262 1 PMID:27718072 -2.5.1.18 4-methylumbelliferyl acetate gelatoporia subvermispora 0.00333 0.00333 1 PMID:30928378 -2.5.1.18 4-nitrobenzyl chloride acidovorax sp. kks102 0.27 0.27 1 PMID:29779193 -2.5.1.18 4-nitrophenyl butyrate phanerodontia chrysosporium 27.6 27.6 1 PMID:23007392 -2.5.1.18 4-nitroquinoline-1-oxide fasciola gigantica 3.9 3.9 1 PMID:29235505 -2.5.1.18 5-androstene-3,17-dione sus scrofa 4.8 4.8 1 PMID:21172301 -2.5.1.18 5-chloromethylfluorescein diacetate gelatoporia subvermispora 0.000714 0.000714 1 PMID:30928378 -2.5.1.18 5-pregnene-3,20-dione sus scrofa 0.01 0.01 1 PMID:21172301 -2.5.1.18 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole oryza sativa 0.257 0.257 1 PMID:19640724 -2.5.1.18 7-oxabicyclo[4.1.0]heptan-2-one schistosoma japonicum 0.037 0.037 1 PMID:17226963 -2.5.1.18 acrolein arabidopsis thaliana 1.78 1.78 1 PMID:27718072 -2.5.1.18 acrolein spinacia oleracea 1.15 1.15 1 PMID:27718072 -2.5.1.18 alachlor zea mays 0.00048 0.00048 1 PMID:15906083 -2.5.1.18 allyl-isothiocyanate populus trichocarpa 3.6 1.925 2 PMID:26026470 -2.5.1.18 alpha-o-(beta-methylumbelliferyl)acetovanillone gelatoporia subvermispora 4.51e-07 4.51e-07 1 PMID:30928378 -2.5.1.18 beta-(2-methoxyphenoxy)-gamma-hydroxypropiovanillone novosphingobium aromaticivorans 2.9 2.9 1 PMID:30541921 -2.5.1.18 cumene hydroperoxide camelus dromedarius 9.03 9.03 1 PMID:27639582 -2.5.1.18 cumene hydroperoxide gelatoporia subvermispora 0.21 0.21 1 PMID:30928378 -2.5.1.18 cumene hydroperoxide homo sapiens 9600.0 9600.0 1 * -2.5.1.18 cumene hydroperoxide populus trichocarpa 0.58 0.425 2 PMID:26026470 -2.5.1.18 dehydroascorbate danio rerio 11.9 11.9 1 PMID:25461745 -2.5.1.18 dehydroascorbate drosophila melanogaster 925.2 799.45 2 PMID:24533905 -2.5.1.18 dehydroascorbate phanerodontia chrysosporium 1.26 1.26 1 PMID:23063695 -2.5.1.18 dichloroacetate synechocystis sp. 82.17 82.17 1 PMID:25685659 -2.5.1.18 dichloroacetic acid danio rerio 0.002 0.002 1 PMID:25461745 -2.5.1.18 ethacrynic acid anopheles dirus 0.28 0.28 1 PMID:18760991 -2.5.1.18 ethacrynic acid danio rerio 2.24 1.735 2 PMID:25461745 -2.5.1.18 gamma-glu-cys-aib homo sapiens 1.91 1.91 1 PMID:27037874 -2.5.1.18 gamma-glu-cys-sar homo sapiens 0.39 0.39 1 PMID:27037874 -2.5.1.18 glutathione acidovorax sp. kks102 0.086 0.086 1 PMID:29779193 -2.5.1.18 glutathione aedes aegypti 51.0 17.0 8 PMID:21195177 -2.5.1.18 glutathione agrobacterium tumefaciens 0.53 0.28500000000000003 2 PMID:22496785 -2.5.1.18 glutathione anopheles gambiae 0.2 0.2 1 PMID:18569345 -2.5.1.18 glutathione bombyx mori 57.87 57.87 1 * -2.5.1.18 glutathione bos taurus 7.95 7.95 1 PMID:18221006 -2.5.1.18 glutathione brucella anthropi 16.51 16.51 1 PMID:18076047 -2.5.1.18 glutathione camelus dromedarius 9.03 4.62 3 PMID:27639582 -2.5.1.18 glutathione danio rerio 129.0 16.6 9 PMID:25461745 -2.5.1.18 glutathione drosophila melanogaster 905.8 799.3 2 PMID:24533905 -2.5.1.18 glutathione escherichia coli 7.7 7.7 1 PMID:18778244 -2.5.1.18 glutathione glycine max 2.65 0.7 8 PMID:25479053;PMID:27103493 -2.5.1.18 glutathione homo sapiens 47.3 7.67 5 PMID:17046132;PMID:21728995;PMID:27037874;PMID:6517933 -2.5.1.18 glutathione lucilia cuprina 53.0 53.0 1 PMID:9368035 -2.5.1.18 glutathione monopterus albus 3.82 3.82 1 * -2.5.1.18 glutathione mucor mucedo 552.0 295.9 2 PMID:16209109 -2.5.1.18 glutathione mus musculus 2286.0 2286.0 1 PMID:16507568 -2.5.1.18 glutathione musca domestica 14.0 14.0 1 PMID:23268341 -2.5.1.18 glutathione nilaparvata lugens 1.62 1.62 1 PMID:25497345 -2.5.1.18 glutathione oryza sativa 0.264 0.264 2 PMID:19640724;PMID:31878175 -2.5.1.18 glutathione paraburkholderia xenovorans 0.24 0.16 3 PMID:16740949 -2.5.1.18 glutathione penaeus vannamei 274.4 274.4 1 PMID:17427177 -2.5.1.18 glutathione phanerodontia chrysosporium 11.03 11.03 1 PMID:23007392 -2.5.1.18 glutathione proteus mirabilis 12.4 6.640000000000001 2 PMID:20663851 -2.5.1.18 glutathione rattus norvegicus 7.33 7.33 1 PMID:6838589 -2.5.1.18 glutathione salix babylonica 16.714 6.837 14 PMID:32308662 -2.5.1.18 glutathione spinacia oleracea 0.0709 0.0709 1 PMID:27718072 -2.5.1.18 glutathione sus scrofa 141.7 141.7 1 PMID:25640718 -2.5.1.18 glutathione synechococcus elongatus 48.7 48.7 1 PMID:17484723 -2.5.1.18 glutathione synechocystis sp. 15.48 15.48 1 PMID:25685659 -2.5.1.18 glutathione taenia crassiceps 9.63 6.295 2 PMID:29032785 -2.5.1.18 glutathione tetranychus urticae 0.39 0.027 3 PMID:26047112 -2.5.1.18 glutathione thermosynechococcus vestitus 17.0 17.0 1 PMID:17484723 -2.5.1.18 glutathione trichinella spiralis 4.3 4.3 1 PMID:25758588 -2.5.1.18 glutathione triticum aestivum 16.4 16.4 1 PMID:25640718 -2.5.1.18 gsh anopheles dirus 18.6 18.6 1 PMID:12708968 -2.5.1.18 gsh atactodea striata 551.0 551.0 1 PMID:12893269 -2.5.1.18 gsh homo sapiens 1370.0 437.0 4 PMID:12852784 -2.5.1.18 gsh macrobrachium vollenhovenii 20.3 20.3 1 PMID:15674845 -2.5.1.18 gsh pinus tabuliformis 6.7 6.59 2 PMID:15820751;PMID:15862305 -2.5.1.18 gsh schistosoma japonicum 16.6 9.600000000000001 2 PMID:15358220 -2.5.1.18 gsh solenopsis invicta 74.5 74.5 1 PMID:14505691 -2.5.1.18 hexa-2,4-dienal fasciola gigantica 3.47 3.47 1 PMID:29235505 -2.5.1.18 hyp-cys-gly homo sapiens 1.04 1.04 1 PMID:27037874 -2.5.1.18 iodobutane homo sapiens 0.037 0.037 1 PMID:20097269 -2.5.1.18 iodobutane rattus norvegicus 0.215 0.215 1 PMID:20097269 -2.5.1.18 iodohexane homo sapiens 0.068 0.068 1 PMID:20097269 -2.5.1.18 iodohexane rattus norvegicus 3.52 3.52 1 PMID:20097269 -2.5.1.18 iodomethane homo sapiens 9.16 9.16 1 PMID:20097269 -2.5.1.18 iodomethane rattus norvegicus 349.0 349.0 1 PMID:20097269 -2.5.1.18 l-gamma-glutamyl-s-[2-hydroxy-3-methoxy-1-(4-methoxyphenyl)-3-oxopropyl]-l-cysteinylglycine schistosoma japonicum 39.0 39.0 1 PMID:17226963 -2.5.1.18 maleylacetone homo sapiens 464.0 232.1735 2 PMID:12852784 -2.5.1.18 methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate schistosoma japonicum 0.63 0.63 1 PMID:17226963 -2.5.1.18 phenethyl isothiocyanate camelus dromedarius 3.0 3.0 1 PMID:27639582 -2.5.1.18 phenethyl isothiocyanate phanerodontia chrysosporium 8.52 5.1049999999999995 2 PMID:23007392;PMID:23063695 -2.5.1.18 phenethyl isothiocyanate populus trichocarpa 62.9 31.52 2 PMID:26026470 -2.5.1.18 phenethyl isothiocyanate sus scrofa 9.5 9.5 1 PMID:21172301 -2.5.1.18 phenethyl-isothiocyanate synechococcus elongatus 63.4 63.4 1 PMID:17484723 -2.5.1.18 phenethyl-isothiocyanate thermosynechococcus vestitus 21.4 21.4 1 PMID:17484723 -2.5.1.18 reduced glutathione anopheles dirus 26.1 25.65 2 PMID:15705499;PMID:16153184 -2.5.1.18 reduced glutathione pseudomonas putida 39.0 39.0 1 PMID:17508726 -2.5.1.18 s-phenylacetylglutathione phanerodontia chrysosporium 180.0 180.0 1 PMID:23063695 -2.5.1.18 styrene 7,8-oxide callithrix jacchus 4.12 2.4 6 PMID:32027883 -2.5.1.18 sulforaphane populus trichocarpa 2.57 1.3215 2 PMID:26026470 -2.5.1.18 tic-cys-gly homo sapiens 0.31 0.31 1 PMID:27037874 -2.5.1.18 trans-2-nonenal fasciola gigantica 4.38 4.38 1 PMID:29235505 -2.5.1.18 trans-2-nonenal sus scrofa 0.155 0.155 1 PMID:21172301 -2.5.1.18 trans-4-phenyl-3-butene-2-one fasciola gigantica 11.28 11.28 1 PMID:29235505 -2.5.1.18 trans-o-hydroxybenzylidene pyruvic acid pseudomonas putida 19.0 19.0 1 PMID:17508726 -2.5.1.19 3-phosphoshikimate escherichia coli 100.0 44.3 4 PMID:1344882;PMID:19271774 -2.5.1.19 3-phosphoshikimate neurospora crassa 33.6 33.6 1 PMID:3157372 -2.5.1.19 3-phosphoshikimate staphylococcus aureus 4.2 4.2 1 PMID:15670836 -2.5.1.19 5-enolpyruvylshikimate 3-phosphate escherichia coli 1.2e-05 1.2e-05 1 PMID:17256973 -2.5.1.19 5-enolpyruvylshikimate 3-phosphate pseudomonas aeruginosa 7.4 7.4 2 * -2.5.1.19 5-enolpyruvylshikimate 3-phosphate streptococcus pneumoniae 0.23 0.23 1 PMID:10601870 -2.5.1.19 phosphate pseudomonas aeruginosa 5.4 5.4 2 * -2.5.1.19 phosphate streptococcus pneumoniae 0.22 0.22 1 PMID:10601870 -2.5.1.19 phosphoenolpyruvate bacillus cereus 31.8 31.8 1 PMID:23161452 -2.5.1.19 phosphoenolpyruvate bacteria 28.3 28.3 1 PMID:18172892 -2.5.1.19 phosphoenolpyruvate brucella anthropi 26.7 26.7 1 PMID:21948846 -2.5.1.19 phosphoenolpyruvate escherichia coli 100.0 14.0 7 PMID:17256973;PMID:18567546;PMID:19271774 -2.5.1.19 phosphoenolpyruvate neurospora crassa 33.6 33.6 1 PMID:3157372 -2.5.1.19 phosphoenolpyruvate plant 38.4 38.4 1 PMID:18172892 -2.5.1.19 phosphoenolpyruvate pseudomonas fluorescens 26.2 26.2 1 PMID:23090479 -2.5.1.19 phosphoenolpyruvate staphylococcus aureus 4.3 4.3 1 PMID:15670836 -2.5.1.19 phosphoenolpyruvate streptococcus pneumoniae 12.8 2.8 5 PMID:10601870 -2.5.1.2 4-nitrothiophenolate paenibacillus thiaminolyticus 297.0 297.0 2 PMID:17603991 -2.5.1.2 thiamine clostridium botulinum 231.0 231.0 1 PMID:24079939 -2.5.1.2 thiamine paenibacillus thiaminolyticus 260.0 260.0 2 PMID:17603991 -2.5.1.21 (2e,6e)-farnesyl diphosphate aspergillus flavus 0.027 0.027 1 PMID:30904161 -2.5.1.21 (2e,6e)-farnesyl diphosphate methylococcus capsulatus 0.478 0.478 1 PMID:25283713 -2.5.1.21 farnesyl diphosphate saccharomyces cerevisiae 3.3 1.915 2 PMID:8239656;PMID:8323279 -2.5.1.21 farnesyl diphosphate thermosynechococcus vestitus 1.74 1.74 1 PMID:18375558 -2.5.1.21 nadph aspergillus flavus 0.039 0.039 1 PMID:30904161 -2.5.1.21 nadph methylococcus capsulatus 0.478 0.478 1 PMID:25283713 -2.5.1.22 spermidine homo sapiens 32.0 32.0 2 PMID:18367445;PMID:18390925 -2.5.1.27 1-hydroxy-2-methyl-2-(e)-butenyl 4-diphosphate agrobacterium tumefaciens 0.025 0.025 1 PMID:18258747 -2.5.1.27 adp humulus lupulus 0.024 0.024 1 PMID:15381407 -2.5.1.27 adp morus alba 0.0235 0.0235 1 PMID:17320045 -2.5.1.27 amp humulus lupulus 0.00828 0.00828 1 PMID:15381407 -2.5.1.27 atp humulus lupulus 0.022 0.022 1 PMID:15381407 -2.5.1.27 dimethylallyl diphosphate agrobacterium tumefaciens 0.053 0.053 1 PMID:18258747 -2.5.1.27 dimethylallyl diphosphate humulus lupulus 0.027 0.027 1 PMID:15381407 -2.5.1.27 dimethylallyl diphosphate morus alba 0.0345 0.0345 1 PMID:17320045 -2.5.1.28 dimethylallyl diphosphate solanum habrochaites 0.026 0.026 1 PMID:24291644 -2.5.1.28 dimethylallyl diphosphate solanum lycopersicum 0.2 0.2 1 PMID:19487664 -2.5.1.28 isopentenyl diphosphate solanum habrochaites 0.047 0.047 1 PMID:24291644 -2.5.1.29 (2e,6e)-farnesyl diphosphate corynebacterium glutamicum 0.4 0.25 2 PMID:25181035 -2.5.1.29 (2e,6e)-farnesyl diphosphate lutzomyia longipalpis 0.065 0.065 1 PMID:37619821 -2.5.1.29 (2e,6e)-farnesyl diphosphate plasmodium vivax 0.8 0.8 1 PMID:21084289 -2.5.1.29 (2e,6e)-farnesyl diphosphate saccharomyces cerevisiae 0.037 0.037 1 PMID:23534508 -2.5.1.29 (e,e)-farnesyl diphosphate saccharomyces cerevisiae 0.025 0.025 1 PMID:19245203 -2.5.1.29 dimethylallyl diphosphate picea abies 1.4 1.4 1 PMID:19939949 -2.5.1.29 dimethylallyl diphosphate plasmodium vivax 0.5 0.5 1 PMID:21084289 -2.5.1.29 dimethylallyl diphosphate taxus canadensis 1.0 1.0 1 PMID:11733504 -2.5.1.29 farnesyl diphosphate taxus canadensis 3.3 3.3 1 PMID:11733504 -2.5.1.29 geranyl diphosphate plasmodium vivax 0.5 0.5 1 PMID:21084289 -2.5.1.29 geranyl diphosphate taxus canadensis 2.1 2.1 1 PMID:11733504 -2.5.1.29 isopentenyl diphosphate corynebacterium glutamicum 1.1 0.56 2 PMID:25181035 -2.5.1.29 isopentenyl diphosphate lutzomyia longipalpis 0.02 0.02 1 PMID:37619821 -2.5.1.29 isopentenyl diphosphate plasmodium vivax 0.8 0.8 1 PMID:21084289 -2.5.1.29 isopentenyl diphosphate saccharomyces cerevisiae 0.037 0.037 1 PMID:23534508 -2.5.1.29 trans,trans-farnesyl diphosphate homo sapiens 0.204 0.204 1 PMID:16698791 -2.5.1.29 trans,trans-farnesyl diphosphate saccharomyces cerevisiae 2.5 2.5 1 PMID:16554305 -2.5.1.31 (2e,6e)-8-(n-methyl-2-aminobenzoyloxy)-3,7-dimethyl-2,6-octandien-1-diphosphate escherichia coli 11.2 11.2 1 PMID:21704016 -2.5.1.31 (2e,6e)-farnesyl diphosphate escherichia coli 2.5 2.5 12 PMID:10978182;PMID:11076526;PMID:11581264;PMID:11744728;PMID:12756244;PMID:14661956;PMID:15447632;PMID:15788389;PMID:21704016 -2.5.1.31 (2e,6e)-farnesyl diphosphate helicobacter pylori 0.22 0.22 2 PMID:18382620 -2.5.1.31 (2e,6e)-farnesyl diphosphate micrococcus luteus 1.66 1.44 2 PMID:11098133;PMID:12680756 -2.5.1.31 (2e,6e)-farnesyl thiodiphosphate escherichia coli 3.1e-07 3.1e-07 1 PMID:11744728 -2.5.1.31 (2z,6e,10e)-geranylgeranyl diphosphate micrococcus luteus 1.77 1.77 2 PMID:11098133;PMID:12680756 -2.5.1.31 (z,e,e)-geranylgeranyl diphosphate micrococcus luteus 1.77 1.77 1 PMID:11098133 -2.5.1.31 7-(2,6-dimethyl-8-diphospho-2,6-octadienyloxy)-8-methyl-4-trifluoromethyl-chromen-2-one geranyl diphosphate escherichia coli 0.02 0.02 1 PMID:12487597 -2.5.1.31 farnesyl diphosphate escherichia coli 2.5 2.5 2 PMID:12756244;PMID:15447632;PMID:15788389 -2.5.1.31 farnesyl diphosphate helicobacter pylori 0.22 0.22 1 PMID:18382620 -2.5.1.31 farnesyl diphosphate micrococcus luteus 1.66 1.22 3 PMID:11098133;PMID:12680756;PMID:14769870 -2.5.1.31 geranyl diphosphate escherichia coli 1.7 1.7 1 PMID:15447632 -2.5.1.31 geranylgeranyl diphosphate escherichia coli 2.1 2.1 2 PMID:15447632 -2.5.1.31 isopentenyl diphosphate escherichia coli 2.5 2.5 1 PMID:12756244 -2.5.1.31 isopentenyl diphosphate helicobacter pylori 0.22 0.22 1 PMID:18382620 -2.5.1.31 isopentenyl diphosphate micrococcus luteus 1.85 1.7000000000000002 2 PMID:11098133;PMID:14769870 -2.5.1.31 isopentenyl diphosphate saccharomyces cerevisiae 0.0002 0.0002 1 PMID:11722180 -2.5.1.34 2-pentenyl diphosphate aspergillus fumigatus 0.011 0.011 1 PMID:22958207 -2.5.1.34 4-amino-l-tryptophan claviceps purpurea 0.42 0.42 1 PMID:23301871 -2.5.1.34 4-methoxy-l-tryptophan claviceps purpurea 1.3 1.3 1 PMID:23301871 -2.5.1.34 4-methyl-l-tryptophan claviceps purpurea 0.75 0.75 1 PMID:23301871 -2.5.1.34 5-hydroxy-l-tryptophan aspergillus fumigatus 0.165 0.165 1 PMID:17577899 -2.5.1.34 5-hydroxy-l-tryptophan malbranchea aurantiaca 0.56 0.56 1 PMID:18390548 -2.5.1.34 5-methyl-dl-tryptophan aspergillus fumigatus 0.125 0.09665 2 PMID:17577899;PMID:24657051 -2.5.1.34 6-methyl-dl-tryptophan aspergillus fumigatus 0.0533 0.0533 1 PMID:17577899 -2.5.1.34 7-methyl-dl-tryptophan aspergillus fumigatus 0.1267 0.1267 1 PMID:17577899 -2.5.1.34 alpha-methyl-dl-tryptophan aspergillus fumigatus 0.1033 0.1033 1 PMID:17577899 -2.5.1.34 ardeemin fumiquinazoline aspergillus fumigatus 0.009 0.009 1 * -2.5.1.34 cyclo-l-tryptophan-glycine aspergillus fumigatus 0.00106 0.00106 1 PMID:19277607 -2.5.1.34 cyclo-l-tryptophan-l-leucine aspergillus fumigatus 0.0017 0.0017 1 PMID:19277607 -2.5.1.34 cyclo-l-tryptophan-l-proline aspergillus fumigatus 0.00113 0.00113 1 PMID:19277607 -2.5.1.34 cyclo-l-tryptophan-l-tryptophan aspergillus fumigatus 0.0021 0.0021 1 PMID:19277607 -2.5.1.34 cyclo-l-tryptophan-l-tyrosine aspergillus fumigatus 0.0017 0.0017 1 PMID:19277607 -2.5.1.34 dia-ardeemin fumiquinazoline aspergillus fumigatus 0.009 0.009 1 * -2.5.1.34 dimethylallyl diphosphate aspergillus fumigatus 0.917 0.6935 2 PMID:21766851;PMID:24657051 -2.5.1.34 ent-ardeemin fumiquinazoline aspergillus fumigatus 0.0016 0.0016 1 * -2.5.1.34 indole-3-propionic acid aspergillus fumigatus 0.2683 0.2683 1 PMID:17577899 -2.5.1.34 l-abrine aspergillus fumigatus 0.043 0.043 1 PMID:24657051 -2.5.1.34 l-beta-homotryptophan aspergillus fumigatus 0.3767 0.3767 1 PMID:17577899 -2.5.1.34 l-m-tyrosine aspergillus fumigatus 0.0065 0.0065 1 PMID:26077893 -2.5.1.34 l-o-tyrosine aspergillus fumigatus 0.29 0.29 1 PMID:26077893 -2.5.1.34 l-tryptophan aspergillus fumigatus 0.47 0.26335 4 PMID:17577899;PMID:19277607;PMID:21766851;PMID:24657051 -2.5.1.34 l-tryptophan claviceps purpurea 60.0 60.0 1 PMID:23301871 -2.5.1.34 l-tryptophan malbranchea aurantiaca 1.4 1.37 2 PMID:18390548 -2.5.1.34 l-tryptophan methyl ester aspergillus fumigatus 0.1367 0.12685 2 PMID:17577899;PMID:24657051 -2.5.1.34 methylallyl diphosphate aspergillus fumigatus 0.009 0.009 1 PMID:22958207 -2.5.1.34 n-methyl-l-tryptophan aspergillus fumigatus 0.252 0.252 1 PMID:17577899 -2.5.1.34 nalpha-methyl-l-tryptophan malbranchea aurantiaca 1.06 1.06 1 PMID:18390548 -2.5.1.44 putrescine acinetobacter tartarogenes 8.0 8.0 1 PMID:20194510 -2.5.1.44 putrescine blastochloris viridis 1.2 1.2 1 PMID:20194510 -2.5.1.44 putrescine bradyrhizobium japonicum 1.18 1.18 1 PMID:20194510 -2.5.1.45 putrescine senecio vernalis 0.0032 0.0032 1 PMID:12562768 -2.5.1.46 [eif5a-precursor]-l-lysine senecio vernalis 0.0022 0.0022 1 PMID:12562768 -2.5.1.46 [eif5a-precursor]-lysine trypanosoma brucei brucei 0.018 0.018 2 PMID:23525104 -2.5.1.46 nad+ trypanosoma brucei brucei 0.15 0.15 1 PMID:30197036 -2.5.1.46 spermidine trypanosoma brucei brucei 0.18 0.015 3 PMID:23525104;PMID:30197036 -2.5.1.47 beta-chloro-l-alanine geobacillus stearothermophilus 154.0 154.0 1 PMID:15308337 -2.5.1.47 h2s aeropyrum pernix 202.0 202.0 1 PMID:12644499 -2.5.1.47 h2s fusobacterium nucleatum subsp. nucleatum 6.3 6.3 1 PMID:31398016 -2.5.1.47 h2s streptomyces lavendulae 12.0 12.0 1 PMID:26207937 -2.5.1.47 hydrogen sulfide leucaena leucocephala 32.65 17.54 2 PMID:31828681 -2.5.1.47 hydrogen sulfide mimosa pudica 32.99 32.99 1 PMID:29181648 -2.5.1.47 hydrogen sulfide streptomyces lavendulae 12.0 12.0 1 PMID:23529730 -2.5.1.47 l-cys trichomonas vaginalis 6.6 6.6 1 PMID:16735516 -2.5.1.47 o-acetyl-l-ser aeropyrum pernix 202.0 113.0 2 PMID:12644499 -2.5.1.47 o-acetyl-l-ser escherichia coli 733.0 733.0 1 * -2.5.1.47 o-acetyl-l-ser leucaena leucocephala 72.83 58.175 2 PMID:31828681 -2.5.1.47 o-acetyl-l-ser mimosa pudica 33.56 33.56 1 PMID:29181648 -2.5.1.47 o-acetyl-l-ser salmonella enterica subsp. enterica serovar typhimurium 733.0 733.0 1 * -2.5.1.47 o-acetyl-l-ser trichomonas vaginalis 153.0 153.0 1 PMID:16735516 -2.5.1.47 o-acetyl-l-serine bacillus anthracis 4.46 2.58 2 PMID:28921884 -2.5.1.47 o-acetyl-l-serine escherichia coli 24.0 24.0 1 PMID:17894825 -2.5.1.47 o-acetyl-l-serine fusobacterium nucleatum subsp. nucleatum 6.3 6.3 1 PMID:31398016 -2.5.1.47 o-acetyl-l-serine microcystis aeruginosa 232.0 175.5 6 PMID:24275508 -2.5.1.47 o-phosphoserine trichomonas vaginalis 165.0 165.0 1 PMID:16735516 -2.5.1.47 o3-acetyl-l-serine arabidopsis thaliana 1780.0 1780.0 1 PMID:16166087 -2.5.1.47 o3-acetyl-l-serine corynebacterium glutamicum 238.0 238.0 1 PMID:15277766 -2.5.1.47 o3-acetyl-l-serine geobacillus stearothermophilus 312.0 312.0 1 PMID:15308337 -2.5.1.47 o3-acetyl-l-serine salmonella enterica subsp. enterica serovar typhimurium 0.56 0.56 2 PMID:18243146;PMID:18275838 -2.5.1.47 sulfide arabidopsis thaliana 2170.0 2170.0 1 PMID:16166087 -2.5.1.47 thiosulfate aeropyrum pernix 24.0 24.0 1 PMID:12644499 -2.5.1.47 thiosulfate streptomyces lavendulae 0.72 0.72 1 PMID:23529730 -2.5.1.48 cystathionine escherichia coli 7.67 7.67 1 PMID:2405903 -2.5.1.48 l-cystathionine escherichia coli 121.0 121.0 1 PMID:19370061 -2.5.1.48 l-cysteine escherichia coli 121.0 119.0 2 PMID:14503880 -2.5.1.48 o-succinyl-l-homoserine escherichia coli 121.0 112.0 5 PMID:14503880;PMID:19370061;PMID:22855027 -2.5.1.48 o-succinyl-l-homoserine helicobacter pylori 0.297 0.297 1 PMID:17981822 -2.5.1.48 o-succinyl-l-homoserine salmonella enterica subsp. enterica serovar typhimurium 63.3 12.7 3 PMID:4893684 -2.5.1.48 o-succinyl-l-serine salmonella enterica subsp. enterica serovar typhimurium 3.83 1.5 3 PMID:4893684 -2.5.1.49 hydrogen sulfide clostridioides difficile 96.65 96.65 1 PMID:31359602 -2.5.1.49 methanethiol clostridioides difficile 96.65 96.65 1 PMID:31359602 -2.5.1.49 o-acetyl-l-homoserine clostridioides difficile 94.12 94.12 1 PMID:31359602 -2.5.1.54 (3s)-2-deoxyerythrose 4-phosphate escherichia coli 0.233 0.233 1 PMID:15837321 -2.5.1.54 d-erythrose 4-phosphate actinosynnema pretiosum subsp. auranticum 0.03 0.03 1 PMID:22326798 -2.5.1.54 d-erythrose 4-phosphate corynebacterium glutamicum 1.14 0.72 2 PMID:18621870 -2.5.1.54 d-erythrose 4-phosphate escherichia coli 122.0 26.5 6 PMID:10988284;PMID:11732901;PMID:15837321;PMID:9387;PMID:9398312 -2.5.1.54 d-erythrose 4-phosphate neisseria meningitidis 27.1 20.950000000000003 2 PMID:23754471;PMID:26828675 -2.5.1.54 d-erythrose 4-phosphate pseudomonas aeruginosa 19.8 19.8 1 PMID:30242059 -2.5.1.54 d-erythrose 4-phosphate pyrococcus furiosus 5.5 5.5 1 PMID:24239948 -2.5.1.54 d-erythrose 4-phosphate thermotoga maritima 11.7 11.7 1 PMID:23916814 -2.5.1.54 phosphoenolpyruvate actinosynnema pretiosum subsp. auranticum 0.032 0.032 1 PMID:22326798 -2.5.1.54 phosphoenolpyruvate aeropyrum pernix 1.0 1.0 1 PMID:22035970 -2.5.1.54 phosphoenolpyruvate bacillus subtilis 4.6 4.6 1 PMID:15869469 -2.5.1.54 phosphoenolpyruvate corynebacterium glutamicum 1.65 0.35 3 PMID:11381336;PMID:18621870 -2.5.1.54 phosphoenolpyruvate escherichia coli 122.0 32.0 8 PMID:10988284;PMID:11732901;PMID:15378531;PMID:15882071;PMID:27933795;PMID:9056491;PMID:9387;PMID:9398312 -2.5.1.54 phosphoenolpyruvate helicobacter pylori 3.3 3.3 1 PMID:15853768 -2.5.1.54 phosphoenolpyruvate neisseria meningitidis 27.1 26.05 2 PMID:23754471;PMID:26828675 -2.5.1.54 phosphoenolpyruvate pyrococcus furiosus 5.5 1.7 7 PMID:14766297;PMID:16142893;PMID:24239948 -2.5.1.54 phosphoenolpyruvate thermotoga maritima 11.7 6.3 4 PMID:12743122;PMID:23916814 -2.5.1.54 phosphoenolpyruvate uncultured bacterium 17.3 17.3 1 PMID:30715617 -2.5.1.55 2-deoxy-d-ribose 5-phosphate acidithiobacillus ferrooxidans 0.66 0.66 1 PMID:21438567 -2.5.1.55 2-deoxy-d-ribose 5-phosphate neisseria meningitidis 0.13 0.13 1 PMID:21438567 -2.5.1.55 2-deoxyribose 5-phosphate escherichia coli 0.12 0.12 1 PMID:12718525 -2.5.1.55 d-arabinose 5-phosphate acidithiobacillus ferrooxidans 4.8 4.8 2 PMID:20406700;PMID:21438567 -2.5.1.55 d-arabinose 5-phosphate aquifex aeolicus 2.0 0.87 5 PMID:10491295;PMID:16156656 -2.5.1.55 d-arabinose 5-phosphate aquifex pyrophilus 9.0 6.5 2 PMID:12955602;PMID:15308670 -2.5.1.55 d-arabinose 5-phosphate arabidopsis thaliana 5.9 5.9 3 PMID:15070398;PMID:23974348 -2.5.1.55 d-arabinose 5-phosphate escherichia coli 6.8 6.449999999999999 4 PMID:11904225;PMID:12718525;PMID:15308670;PMID:23974348 -2.5.1.55 d-arabinose 5-phosphate helicobacter pylori 1.08 0.49 3 PMID:11244581;PMID:11904225 -2.5.1.55 d-arabinose 5-phosphate neisseria gonorrhoeae 1.0 1.0 1 PMID:10940049 -2.5.1.55 d-arabinose 5-phosphate neisseria meningitidis 8.0 2.7 7 PMID:18930408;PMID:21438567;PMID:23746359 -2.5.1.55 d-arabinose 5-phosphate salmonella enterica subsp. enterica serovar typhimurium 5.6 3.675 2 PMID:10913123 -2.5.1.55 l-xylose 5-phosphate neisseria meningitidis 1.1 1.1 1 PMID:18930408 -2.5.1.55 phosphoenolpyruvate aquifex aeolicus 2.0 0.46499999999999997 12 PMID:10491295;PMID:16156656;PMID:19228070 -2.5.1.55 phosphoenolpyruvate aquifex pyrophilus 9.0 6.5 2 PMID:12955602;PMID:15308670 -2.5.1.55 phosphoenolpyruvate arabidopsis thaliana 5.9 5.9 3 PMID:15070398;PMID:23974348 -2.5.1.55 phosphoenolpyruvate escherichia coli 100.0 6.449999999999999 4 PMID:11904225;PMID:15308670;PMID:15979047;PMID:23974348 -2.5.1.55 phosphoenolpyruvate helicobacter pylori 1.08 0.3165 8 PMID:11244581;PMID:11904225;PMID:14701842 -2.5.1.55 phosphoenolpyruvate neisseria gonorrhoeae 1.0 1.0 1 PMID:10940049 -2.5.1.55 phosphoenolpyruvate neisseria meningitidis 8.0 8.0 1 PMID:19447118 -2.5.1.55 phosphoenolpyruvate salmonella enterica subsp. enterica serovar typhimurium 6.7 4.390000000000001 2 PMID:10913123 -2.5.1.56 n-acetyl-d-mannosamine campylobacter jejuni 19.9 19.9 1 PMID:15200387 -2.5.1.56 n-acetyl-d-mannosamine moritella viscosa 3.72 3.72 1 PMID:25498013 -2.5.1.56 n-acetyl-d-mannosamine neisseria meningitidis 0.83 0.83 1 PMID:16274664 -2.5.1.56 n-butanoyl-d-mannosamine campylobacter jejuni 3.5 3.5 1 PMID:15200387 -2.5.1.56 n-pentanoyl-d-mannosamine campylobacter jejuni 0.8 0.8 1 PMID:15200387 -2.5.1.56 n-propanoyl-d-mannosamine campylobacter jejuni 11.8 11.8 1 PMID:15200387 -2.5.1.56 phosphoenolpyruvate campylobacter jejuni 19.0 19.0 1 PMID:15200387 -2.5.1.56 phosphoenolpyruvate moritella viscosa 3.75 3.75 1 PMID:25498013 -2.5.1.57 d-mannose 6-phosphate homo sapiens 0.67 0.3405 2 PMID:16274664;PMID:16503877 -2.5.1.57 n-acetyl-d-mannosamine 6-phosphate homo sapiens 1.31 0.666 2 PMID:16274664;PMID:16503877 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-(2,3,5,6-tetrafluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 3.1 3.1 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-(phenylamino)octa-2,6-dien-1-yl diphosphate rattus norvegicus 0.12 0.065 2 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-(phenylsulfanyl)octa-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.17 0.17 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-[(2-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.166 0.166 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-[(3-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.069 0.069 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-[(4-methylphenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.6 0.6 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-[(4-nitrophenyl)amino]octa-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 1.6 1.6 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-[3-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.21 0.21 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-[3-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.03 0.03 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-[3-(trifluoromethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.13 0.13 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-[4-(1-methylethyl)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.44 0.44 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-[4-(trifluoromethoxy)phenoxy]octa-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.16 0.16 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-[[2-(trifluoromethyl)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.3 0.3 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-[[3-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.4 0.4 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-[[4-(trifluoromethoxy)phenyl]amino]octa-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.27 0.27 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-8-phenoxyocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.3 0.3 1 PMID:18985644 -2.5.1.58 (2e,6e)-3,7-dimethyl-9-phenylnona-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.4 0.4 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(2,3-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.23 0.23 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(2,6-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 1.67 1.67 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(2-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.3 0.3 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(2-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.11 0.11 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(2-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.19 0.19 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(2-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.11 0.11 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(3,4-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.24 0.24 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(3,4-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.11 0.11 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(3,5-dichlorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.19 0.19 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(3,5-difluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.1 0.1 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(3-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.06 0.06 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(3-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.04 0.04 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(3-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.17 0.17 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(3-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.004 0.004 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(3-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.07 0.07 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(4-benzylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.3 0.3 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(4-bromophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.5 0.5 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(4-cyanophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 1.93 1.93 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(4-ethylphenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.28 0.28 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(4-fluorophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.58 0.58 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(4-iodophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.27 0.27 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(4-nitrophenoxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.55 0.55 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(benzyloxy)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.17 0.17 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-(isoxazol-3-ylamino)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.04 0.04 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(2-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.17 0.17 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(2-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl diphosphate rattus norvegicus 0.15 0.15 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(2-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.088 0.088 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(3-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.13 0.13 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(3-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.13 0.13 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(3-ethylphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.08 0.08 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(3-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl diphosphate rattus norvegicus 0.1 0.1 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(3-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.24 0.24 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(3-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.53 0.53 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(4-bromophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.27 0.27 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(4-cyanophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.7 0.7 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(4-fluorophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.095 0.095 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(4-iodophenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.17 0.17 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[(4-methoxyphenyl)amino]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 1.4 1.4 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[3-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 0.44 0.44 1 PMID:18985644 -2.5.1.58 (2e,6e)-8-[4-(hydroxymethyl)phenoxy]-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate rattus norvegicus 1.15 1.15 1 PMID:18985644 -2.5.1.58 (2e,6e)-farnesyl diphosphate aspergillus fumigatus 0.12 0.12 1 PMID:24347326 -2.5.1.58 (2e,6e)-farnesyl diphosphate rattus norvegicus 0.29 0.215 2 PMID:18985644;PMID:22989235 -2.5.1.58 (e)-[4-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]phenyl]-methanyl diphosphate rattus norvegicus 0.053 0.053 1 PMID:22989235 -2.5.1.58 10-benzyloxy-3-methyl-2-decen-1-ol-diphosphate rattus norvegicus 25.0 25.0 1 PMID:11591144 -2.5.1.58 3-(3-methyl-2-butenyl)-7,11-dimethyldodeca-2(z),6(e),10-triene 1-diphosphate rattus norvegicus 0.058 0.024 4 PMID:16101305 -2.5.1.58 6-benzyloxy-3-methyl-2-hexen-1-ol-diphosphate rattus norvegicus 44.0 44.0 1 PMID:11591144 -2.5.1.58 7-benzyloxy-3-methyl-2-hepten-1-ol-diphosphate rattus norvegicus 0.84 0.84 1 PMID:11591144 -2.5.1.58 8-benzyloxy-3-methyl-2-octen-1-ol-diphosphate rattus norvegicus 27.0 27.0 1 PMID:11591144 -2.5.1.58 9-benzyloxy-3-methyl-2-nonen-1-ol-diphosphate rattus norvegicus 43.0 43.0 1 PMID:11591144 -2.5.1.58 [3-[(3-phenoxyphenoxy)methyl]phenyl]-methanyl diphosphate rattus norvegicus 0.29 0.29 1 PMID:22989235 -2.5.1.58 aaa-gpp homo sapiens 0.02 0.02 1 PMID:17279592 -2.5.1.58 apo-gpp homo sapiens 0.042 0.042 1 PMID:17279592 -2.5.1.58 dansyl-gly-cys-lys-thr-gln rattus norvegicus 0.033 0.0275 2 PMID:16101305 -2.5.1.58 dansyl-gly-cys-lys-val-leu rattus norvegicus 0.045 0.03 2 PMID:16101305 -2.5.1.58 dansyl-gly-cys-val-ile-met rattus norvegicus 0.01 0.0095 2 PMID:16101305 -2.5.1.58 dansyl-gly-cys-val-leu-ser rattus norvegicus 0.13 0.094 2 PMID:16101305 -2.5.1.58 farnesyl diphosphate homo sapiens 0.66 0.66 1 PMID:17279592 -2.5.1.58 farnesyl diphosphate rattus norvegicus 100.0 0.045 5 PMID:11591144;PMID:16101305 -2.5.1.58 geranyl diphosphate rattus norvegicus 0.004 0.004 1 PMID:18985644 -2.5.1.58 geranylgeranyl diphosphate rattus norvegicus 15.0 15.0 1 PMID:11591144 -2.5.1.58 hom-gpp homo sapiens 0.08 0.08 1 PMID:17279592 -2.5.1.58 thr-lys-cys-val-ile-met escherichia coli 0.1 0.1 1 PMID:16143290 -2.5.1.58 thr-lys-cys-val-leu-ala escherichia coli 0.08 0.08 1 PMID:16143290 -2.5.1.58 thr-lys-val-ile-phe escherichia coli 0.0025 0.0025 1 PMID:16143290 -2.5.1.58 tkcvia rattus norvegicus 0.046 0.046 1 PMID:16285735 -2.5.1.58 tkcvic rattus norvegicus 0.31 0.31 1 PMID:16285735 -2.5.1.58 tkcvid rattus norvegicus 0.0005 0.0005 1 PMID:16285735 -2.5.1.58 tkcvif rattus norvegicus 0.0082 0.0082 1 PMID:16285735 -2.5.1.58 tkcvii rattus norvegicus 0.001 0.001 1 PMID:16285735 -2.5.1.58 tkcvil rattus norvegicus 0.001 0.001 1 PMID:16285735 -2.5.1.58 tkcvim rattus norvegicus 0.041 0.041 1 PMID:16285735 -2.5.1.58 tkcvin rattus norvegicus 0.013 0.013 1 PMID:16285735 -2.5.1.58 tkcviq rattus norvegicus 0.161 0.161 1 PMID:16285735 -2.5.1.58 tkcvir rattus norvegicus 0.001 0.001 1 PMID:16285735 -2.5.1.58 tkcvis rattus norvegicus 0.21 0.21 1 PMID:16285735 -2.5.1.58 tkcvit rattus norvegicus 0.017 0.017 1 PMID:16285735 -2.5.1.58 tkcviv rattus norvegicus 0.0021 0.0021 1 PMID:16285735 -2.5.1.58 tkcviy rattus norvegicus 0.0017 0.0017 1 PMID:16285735 -2.5.1.59 (biotin-conh-(ch2)5-co-)-npfrekkffcai-leu bos taurus 0.12 0.1 3 PMID:7827082 -2.5.1.59 3,7,11-trimethyl-12-(7-nitro-benzo[1,2,5]-oxadiazo-4-ylamino)-dodeca-2,6,10-trien-1-diphosphate homo sapiens 0.08 0.08 1 PMID:16506760 -2.5.1.59 asp-asp-pro-thr-ala-ser-ala-cys-val-leu-leu homo sapiens 0.021 0.021 1 PMID:16893176 -2.5.1.59 geranylgeranyl diphosphate homo sapiens 0.021 0.021 1 PMID:16893176 -2.5.1.59 geranylgeranyl diphosphate rattus norvegicus 0.02 0.02 1 PMID:8089111 -2.5.1.59 geranylgeranyl diphosphate saccharomyces cerevisiae 0.34 0.34 1 PMID:9109664 -2.5.1.59 gst-cdc42 bos taurus 0.0057 0.0057 1 PMID:7827082 -2.5.1.59 gst-rhoa homo sapiens 0.08 0.08 1 PMID:16506760 -2.5.1.59 ki-ras4a homo sapiens 0.0667 0.0667 1 PMID:9092572 -2.5.1.59 ki-ras4b homo sapiens 0.0767 0.0767 1 PMID:9092572 -2.5.1.59 n-ras homo sapiens 0.0113 0.0113 1 PMID:9092572 -2.5.1.59 ras-cys-val-leu-leu homo sapiens 0.014 0.014 1 PMID:9092572 -2.5.1.59 ras-cys-val-leu-leu rattus norvegicus 0.02 0.02 1 PMID:8089111 -2.5.1.59 thr-lys-cys-val-ile-ala escherichia coli 0.001 0.001 1 PMID:16285735 -2.5.1.59 thr-lys-cys-val-ile-arg escherichia coli 0.001 0.001 1 PMID:16285735 -2.5.1.59 thr-lys-cys-val-ile-asn escherichia coli 0.001 0.001 1 PMID:16285735 -2.5.1.59 thr-lys-cys-val-ile-asp escherichia coli 0.001 0.001 1 PMID:16285735 -2.5.1.59 thr-lys-cys-val-ile-cys escherichia coli 0.0063 0.0063 1 PMID:16285735 -2.5.1.59 thr-lys-cys-val-ile-gln escherichia coli 0.001 0.001 1 PMID:16285735 -2.5.1.59 thr-lys-cys-val-ile-ile escherichia coli 0.048 0.048 1 PMID:16285735 -2.5.1.59 thr-lys-cys-val-ile-leu escherichia coli 0.088 0.088 1 PMID:16285735 -2.5.1.59 thr-lys-cys-val-ile-met escherichia coli 0.082 0.082 1 PMID:16285735 -2.5.1.59 thr-lys-cys-val-ile-phe escherichia coli 0.06 0.06 1 PMID:16285735 -2.5.1.59 thr-lys-cys-val-ile-ser escherichia coli 0.001 0.001 1 PMID:16285735 -2.5.1.59 thr-lys-cys-val-ile-thr escherichia coli 0.001 0.001 1 PMID:16285735 -2.5.1.59 thr-lys-cys-val-ile-tyr escherichia coli 0.022 0.022 1 PMID:16285735 -2.5.1.59 thr-lys-cys-val-ile-val escherichia coli 0.107 0.107 1 PMID:16285735 -2.5.1.6 atp bacteroides fragilis 0.79 0.79 1 PMID:37642924 -2.5.1.6 atp corynebacterium glutamicum 0.544 0.544 1 PMID:37846083 -2.5.1.6 atp escherichia coli 1.22 0.6385 2 PMID:31307578;PMID:36652094 -2.5.1.6 atp homo sapiens 0.27 0.27 1 PMID:33656855 -2.5.1.6 atp lactiplantibacillus plantarum 1.12 1.12 1 PMID:39864752 -2.5.1.6 atp leishmania infantum 8.83e-05 8.83e-05 1 PMID:11698393 -2.5.1.6 atp limosilactobacillus fermentum 1.91 1.91 1 PMID:39864752 -2.5.1.6 atp limosilactobacillus reuteri 0.66 0.66 1 PMID:39864752 -2.5.1.6 atp plasmodium falciparum 1.06 1.06 1 PMID:27466371 -2.5.1.6 atp pyrococcus furiosus 7.5 7.5 1 PMID:25577347 -2.5.1.6 atp saccharolobus solfataricus 0.052 0.044 4 PMID:24649856 -2.5.1.6 atp streptomyces xinghaiensis 0.0012 0.000935 2 PMID:34489034 -2.5.1.6 l-ethionine saccharolobus solfataricus 0.05 0.0445 2 PMID:24649856 -2.5.1.6 l-methionine corynebacterium glutamicum 0.471 0.471 1 PMID:37846083 -2.5.1.6 l-methionine escherichia coli 1.5 1.22 3 PMID:12831838;PMID:31307578;PMID:36652094 -2.5.1.6 l-methionine homo sapiens 0.43 0.35 2 PMID:32091873;PMID:33656855 -2.5.1.6 l-methionine lactiplantibacillus plantarum 1.12 1.12 1 PMID:39864752 -2.5.1.6 l-methionine limosilactobacillus fermentum 1.91 1.91 1 PMID:39864752 -2.5.1.6 l-methionine methanocaldococcus jannaschii 1.46 1.46 1 PMID:19348969 -2.5.1.6 l-methionine mus musculus 0.259 0.259 1 PMID:38943667 -2.5.1.6 l-methionine mycolicibacterium smegmatis 0.93 0.93 1 PMID:12809568 -2.5.1.6 l-methionine plasmodium falciparum 1.06 1.06 1 PMID:27466371 -2.5.1.6 l-methionine pyrococcus furiosus 7.5 7.5 1 PMID:25577347 -2.5.1.6 l-methionine saccharolobus solfataricus 0.049 0.04165 2 PMID:24649856 -2.5.1.6 l-methionine streptomyces xinghaiensis 0.001 0.000665 2 PMID:34489034 -2.5.1.6 s-(-)-methioninol homo sapiens 0.183 0.183 1 PMID:32091873 -2.5.1.6 s-(6-azidohex-2-ynyl)-l-homocysteine mus musculus 0.00028 0.00028 1 PMID:38943667 -2.5.1.6 s-adenosyl-l-methionine escherichia coli 0.47 0.47 1 PMID:39016109 -2.5.1.6 s-adenosylmethionine escherichia coli 0.000417 0.000417 1 PMID:12135357 -2.5.1.6 s-adenosylmethionine leishmania donovani 0.032 0.032 1 PMID:12492472 -2.5.1.6 s-adenosylmethionine leishmania infantum 8.83e-05 8.83e-05 1 PMID:11698393 -2.5.1.6 s-adenosylmethionine rattus norvegicus 0.583 0.583 1 PMID:10811651 -2.5.1.6 tripolyphosphate escherichia coli 1.67e-06 1.67e-06 1 PMID:12135357 -2.5.1.6 tripolyphosphate leishmania donovani 0.004 0.004 1 PMID:12492472 -2.5.1.6 tripolyphosphate rattus norvegicus 0.125 0.125 1 PMID:10811651 -2.5.1.60 rab protein rattus norvegicus 0.013 0.013 1 PMID:17086561 -2.5.1.61 porphobilinogen homo sapiens 0.25 0.25 1 PMID:7354069 -2.5.1.63 5'-deoxy-5'-chloroadenosine streptomyces sp. ma37 0.0022 0.0022 1 PMID:27739177 -2.5.1.63 5-deoxy-5'-bromoadenosine streptantibioticus cattleyicolor 0.0003 0.0003 1 PMID:31364664 -2.5.1.63 fluoride nocardia brasiliensis 0.0012 0.0012 1 PMID:24795808 -2.5.1.63 fluoride streptantibioticus cattleyicolor 2.0 0.0015 4 PMID:14765200;PMID:17985882;PMID:24795808 -2.5.1.63 s-adenosyl-l-methionine nocardia brasiliensis 0.0023 0.0023 1 PMID:24795808 -2.5.1.63 s-adenosyl-l-methionine streptantibioticus cattleyicolor 0.074 0.0021 3 PMID:14765200;PMID:17985882;PMID:24795808 -2.5.1.63 s-adenosyl-l-methionine streptomyces sp. ma37 0.0037 0.0037 1 PMID:27739177 -2.5.1.63 s-adenosyl-l-methionine streptomyces xinghaiensis 0.0047 0.0034 5 PMID:31761913 -2.5.1.65 hydrogen sulfide aeropyrum pernix 730.0 381.5 2 PMID:27377295 -2.5.1.65 o-acetyl-l-serine aeropyrum pernix 202.0 156.0 4 PMID:12644499;PMID:12965218;PMID:27377295 -2.5.1.65 o-phospho-l-serine aeropyrum pernix 14000.0 3050.0 5 PMID:12965218;PMID:27377295 -2.5.1.65 o-phospho-l-serine mycobacterium tuberculosis 0.913 0.2 3 PMID:18799456;PMID:25022854 -2.5.1.65 o3-acetyl-l-serine mycobacterium tuberculosis 0.025 0.025 1 PMID:18842002 -2.5.1.65 o3-phospho-l-serine mycobacterium tuberculosis 17.0 17.0 1 PMID:18842002 -2.5.1.67 dimethylallyl diphosphate artemisia spiciformis 0.005 0.005 1 PMID:28926242 -2.5.1.67 dimethylallyl diphosphate tanacetum cinerariifolium 0.008 0.008 1 PMID:11287653 -2.5.1.68 geranyl diphosphate corynebacterium efficiens 141.0 141.0 1 PMID:18725204 -2.5.1.68 geranyl diphosphate corynebacterium glutamicum 329.0 329.0 1 PMID:18725204 -2.5.1.68 geranyl diphosphate mycobacterium tuberculosis 860.0 860.0 1 PMID:18725204 -2.5.1.68 geranyl diphosphate thermobifida fusca 229.0 229.0 1 PMID:18725204 -2.5.1.68 isopentenyl diphosphate corynebacterium efficiens 173.0 173.0 1 PMID:18725204 -2.5.1.68 isopentenyl diphosphate corynebacterium glutamicum 329.0 329.0 1 PMID:18725204 -2.5.1.68 isopentenyl diphosphate mycobacterium tuberculosis 788.0 788.0 1 PMID:18725204 -2.5.1.68 isopentenyl diphosphate thermobifida fusca 282.0 282.0 1 PMID:18725204 -2.5.1.69 dimethylallyl diphosphate lavandula x intermedia 0.1 0.1 1 PMID:23306202 -2.5.1.7 fosfomycin staphylococcus aureus 1.13 0.945 2 PMID:19298367 -2.5.1.7 phosphoenolpyruvate enterobacter cloacae 3.0 3.0 2 PMID:11027147;PMID:21822642 -2.5.1.7 phosphoenolpyruvate escherichia coli 4.75 4.75 3 PMID:1512209;PMID:21822642 -2.5.1.7 phosphoenolpyruvate haemophilus influenzae 3.5 3.5 1 * -2.5.1.7 phosphoenolpyruvate mycobacterium tuberculosis 0.117 0.117 1 PMID:24463011 -2.5.1.7 phosphoenolpyruvate mycolicibacterium smegmatis 0.058 0.058 1 PMID:24463011 -2.5.1.7 phosphoenolpyruvate pseudomonas aeruginosa 1.8 1.8 1 PMID:21822642 -2.5.1.7 phosphoenolpyruvate staphylococcus aureus 1.13 1.13 1 PMID:21822642 -2.5.1.7 phosphoenolpyruvate streptococcus pneumoniae 0.41 0.41 1 PMID:21822642 -2.5.1.7 udp-glcnac enterobacter cloacae 3.0 3.0 1 PMID:11027147 -2.5.1.7 udp-glcnac escherichia coli 8.9 8.9 1 PMID:11820287 -2.5.1.7 udp-glcnac streptococcus pneumoniae 0.78 0.595 2 PMID:10894720 -2.5.1.7 udp-n-acetyl-alpha-d-glucosamine mycobacterium tuberculosis 0.147 0.147 1 PMID:24463011 -2.5.1.7 udp-n-acetyl-alpha-d-glucosamine mycolicibacterium smegmatis 0.033 0.033 1 PMID:24463011 -2.5.1.7 udp-n-acetyl-d-glucosamine enterobacter cloacae 3.0 3.0 1 PMID:21822642 -2.5.1.7 udp-n-acetyl-d-glucosamine escherichia coli 4.75 4.275 4 PMID:1512209;PMID:21822642 -2.5.1.7 udp-n-acetyl-d-glucosamine haemophilus influenzae 3.5 3.5 1 * -2.5.1.7 udp-n-acetyl-d-glucosamine pseudomonas aeruginosa 2.4 2.1 2 PMID:21822642 -2.5.1.7 udp-n-acetyl-d-glucosamine staphylococcus aureus 1.13 1.13 1 PMID:21822642 -2.5.1.7 udp-n-acetyl-d-glucosamine streptococcus pneumoniae 0.41 0.41 1 PMID:21822642 -2.5.1.75 gcggacucaaaauccgc escherichia coli 0.26 0.26 1 PMID:10828971 -2.5.1.75 ggccauugaaaauggcc escherichia coli 0.67 0.67 1 PMID:10828971 -2.5.1.75 gggaauugaaaauuccc escherichia coli 0.67 0.67 1 PMID:10828971 -2.5.1.75 gggcauugaaaaugccc escherichia coli 0.79 0.79 1 PMID:10828971 -2.5.1.75 ggggauugaaaaagggg escherichia coli 0.001 0.001 1 PMID:10828971 -2.5.1.75 ggggauugaaaaucccc escherichia coli 1.0 1.0 1 PMID:10828971 -2.5.1.75 ggggauugaaagucccc escherichia coli 0.0039 0.0039 1 PMID:10828971 -2.5.1.75 ggggauugagaaucccc escherichia coli 0.75 0.75 1 PMID:10828971 -2.5.1.75 ggggguugaaaaccccc escherichia coli 0.111 0.111 1 PMID:10828971 -2.5.1.75 seventeen-base rna oligonucleotide escherichia coli 0.3 0.245 2 PMID:11327834 -2.5.1.76 l-phosphoserine methanosarcina acetivorans 0.18 0.18 1 PMID:19761441 -2.5.1.78 5-amino-6-ribitylamino-2,4(1h,3h)-pyrimidinedione bacillus subtilis 0.0557 0.0557 1 PMID:12581640 -2.5.1.78 5-amino-6-ribitylamino-2,4(1h,3h)-pyrimidinedione brucella melitensis 0.003 0.003 1 PMID:17854827 -2.5.1.78 5-amino-6-ribitylamino-2,4(1h,3h)-pyrimidinedione mesorhizobium loti 0.04 0.02015 2 PMID:17854827 -2.5.1.78 5-nitro-6-ribitylamino-2,4(1h,3h)-pyrimidinedione bacillus subtilis 0.076 0.066 2 PMID:7622491 -2.5.1.78 l-3,4-dihydroxybutan-2-one 4-phosphate bacillus subtilis 0.076 0.056 3 PMID:12581640;PMID:7622491 -2.5.1.80 5-methyl-dl-tryptophan neosartorya sp. 0.125 0.125 1 PMID:24657051 -2.5.1.80 ardeemin fumiquinazoline aspergillus fumigatus 0.079 0.079 1 * -2.5.1.80 biochanin a aspergillus fumigatus 0.019 0.019 1 PMID:23106077 -2.5.1.80 dia,ent-ardeemin fumiquinazoline aspergillus fumigatus 0.002 0.002 1 * -2.5.1.80 dia-ardeemin fumiquinazoline aspergillus fumigatus 0.053 0.053 1 * -2.5.1.80 dimethylallyl diphosphate neosartorya sp. 0.092 0.092 1 PMID:24657051 -2.5.1.80 ent-ardeemin fumiquinazoline aspergillus fumigatus 0.059 0.059 1 * -2.5.1.80 eriodictyol aspergillus fumigatus 0.39 0.39 1 PMID:23106077 -2.5.1.80 genistein aspergillus fumigatus 0.027 0.027 1 PMID:23106077 -2.5.1.80 hesperetin aspergillus fumigatus 0.026 0.026 1 PMID:23106077 -2.5.1.80 l-abrine neosartorya sp. 0.043 0.043 1 PMID:24657051 -2.5.1.80 l-o-tyrosine aspergillus fumigatus 0.045 0.045 1 PMID:26077893 -2.5.1.80 l-tryptophan aspergillus fumigatus 0.23 0.23 1 PMID:23106077 -2.5.1.80 l-tryptophan aspergillus niger 0.0053 0.0053 1 PMID:24970457 -2.5.1.80 l-tryptophan neosartorya sp. 0.108 0.108 1 PMID:24657051 -2.5.1.80 l-tryptophan methyl ester neosartorya sp. 0.112 0.112 1 PMID:24657051 -2.5.1.80 naringenin aspergillus fumigatus 0.023 0.023 1 PMID:23106077 -2.5.1.80 phloretin aspergillus fumigatus 0.036 0.036 1 PMID:23106077 -2.5.1.81 geranylgeranyl diphosphate leucosceptrum canum 5.17e-06 5.17e-06 1 PMID:26941091 -2.5.1.81 isopentenyl diphosphate leucosceptrum canum 8.2e-06 8.2e-06 1 PMID:26941091 -2.5.1.85 (2e,6e)-farnesyl diphosphate arabidopsis thaliana 3.77 3.77 1 PMID:15784989 -2.5.1.85 (2e,6e)-farnesyl diphosphate trypanosoma cruzi 0.032 0.032 1 PMID:17062572 -2.5.1.85 farnesyl diphosphate arabidopsis thaliana 29.7 29.7 1 PMID:12437513 -2.5.1.85 geranyl diphosphate trypanosoma cruzi 0.065 0.065 1 PMID:17062572 -2.5.1.85 geranylgeranyl diphosphate arabidopsis thaliana 21.0 11.665 2 PMID:12437513;PMID:15784989 -2.5.1.85 geranylgeranyl diphosphate trypanosoma cruzi 0.087 0.087 1 PMID:17062572 -2.5.1.85 isopentenyl diphosphate arabidopsis thaliana 15.0 8.765 4 PMID:12437513;PMID:15784989 -2.5.1.85 isopentenyl diphosphate trypanosoma cruzi 0.217 0.131 3 PMID:17062572 -2.5.1.86 (2e,6e)-farnesyl diphosphate mycobacterium tuberculosis 0.07 0.07 1 PMID:15516568 -2.5.1.86 (2z,6e)-farnesyl diphosphate mycobacterium tuberculosis 11.5 11.5 1 PMID:15516568 -2.5.1.86 geranyl diphosphate mycobacterium tuberculosis 0.06 0.06 1 PMID:15516568 -2.5.1.86 geranylgeranyl diphosphate mycobacterium tuberculosis 0.03 0.03 1 PMID:15516568 -2.5.1.86 isopentenyl diphosphate mycobacterium tuberculosis 0.08 0.08 1 PMID:15516568 -2.5.1.86 neryl diphosphate mycobacterium tuberculosis 0.16 0.16 1 PMID:15516568 -2.5.1.9 6,7-dimethyl-8-(1'-d-ribityl)lumazine bacillus subtilis 2.0 1.6 2 PMID:6766130 -2.5.1.9 6,7-dimethyl-8-(1-d-ribityl)lumazine arabidopsis thaliana 0.027 0.027 1 PMID:15927885 -2.5.1.9 6,7-dimethyl-8-(1-d-ribityl)lumazine escherichia coli 0.267 0.267 1 PMID:15843156 -2.5.1.9 6,7-dimethyl-8-ribityllumazine bacillus subtilis 0.019 0.019 1 PMID:7622491 -2.5.1.9 6,7-dimethyl-8-ribityllumazine escherichia coli 0.00833 0.00833 1 PMID:11278450 -2.5.1.90 (2e,6e)-8-o-(n-methyl-2-aminobenzoyl)-3,7-dimethyl-2,6-octandien-1-diphosphate escherichia coli 0.055 0.055 1 PMID:27428767 -2.5.1.90 (2e,6e)-farnesyl diphosphate escherichia coli 2.0 1.03 2 PMID:22471615;PMID:27428767 -2.5.1.90 (2e,6e)-farnesyl diphosphate thermotoga maritima 0.005 0.005 2 PMID:12479413;PMID:14617622 -2.5.1.90 isopentenyl diphosphate thermotoga maritima 0.005 0.005 1 PMID:12479413 -2.5.1.91 (2e,6e)-farnesyl diphosphate cereibacter sphaeroides 0.147 0.147 1 PMID:16896603 -2.5.1.91 (2e,6e)-farnesyl diphosphate mycobacterium tuberculosis 0.072 0.072 1 PMID:15516568 -2.5.1.91 (2e,6e,10e)-geranylgeranyl diphosphate cereibacter sphaeroides 0.058 0.058 1 PMID:16896603 -2.5.1.91 (2e,6e,10e)-geranylgeranyl diphosphate mycobacterium tuberculosis 0.03 0.03 1 PMID:15516568 -2.5.1.91 (2e,6z)-farnesyl diphosphate mycobacterium tuberculosis 11.5 11.5 1 PMID:15516568 -2.5.1.91 geranyl diphosphate cereibacter sphaeroides 0.067 0.067 1 PMID:16896603 -2.5.1.91 geranyl diphosphate mycobacterium tuberculosis 0.06 0.06 1 PMID:15516568 -2.5.1.91 geranyl geranyl diphosphate cereibacter sphaeroides 0.06 0.06 1 PMID:16896603 -2.5.1.91 isopentenyl diphosphate cereibacter sphaeroides 0.143 0.14150000000000001 2 PMID:16896603 -2.5.1.91 isopentenyl diphosphate mycobacterium tuberculosis 0.08 0.08 1 PMID:15516568 -2.5.1.91 neryl diphosphate mycobacterium tuberculosis 0.052 0.052 1 PMID:15516568 -2.5.1.92 dimethylallyl diphosphate solanum habrochaites 0.055 0.055 1 PMID:24291644 -2.5.1.92 isopentenyl diphosphate solanum habrochaites 0.19 0.19 1 PMID:24291644 -2.5.1.92 neryl diphosphate solanum habrochaites 0.069 0.069 1 PMID:24291644 -2.5.1.94 5'-chloro-5'-deoxyadenosine salinispora tropica cnb-440 0.2 0.2 1 PMID:18059261 -2.5.1.94 5'-deoxy-5'-iodoadenosine salinispora tropica cnb-440 0.83 0.83 1 PMID:18059261 -2.5.1.94 5-deoxy-5'-bromoadenosine streptantibioticus cattleyicolor 0.0003 0.0003 1 PMID:31364664 -2.5.1.94 5-deoxy-5'-chloroadenosine streptomyces noursei 0.208 0.208 1 PMID:30083673 -2.5.1.94 5-deoxy-5'-chloroadenosine umezawaea tangerina 0.248 0.248 1 PMID:30083673 -2.5.1.94 5-deoxy-5-chloroadenosine uncultured bacterium 0.249 0.22849999999999998 2 PMID:30083673 -2.5.1.94 bromide salinispora tropica cnb-440 0.013 0.013 1 PMID:18059261 -2.5.1.94 chloride salinispora tropica cnb-440 0.015 0.015 1 PMID:18059261 -2.5.1.94 iodide salinispora tropica cnb-440 0.005 0.005 1 PMID:18059261 -2.5.1.94 l-methionine salinispora tropica cnb-440 0.2 0.2 1 PMID:18059261 -2.5.1.94 s-adenosyl-l-methionine salinispora tropica cnb-440 0.015 0.015 1 PMID:18059261 -2.5.1.94 s-adenosyl-l-methionine streptomyces noursei 0.078 0.078 1 PMID:30083673 -2.5.1.94 s-adenosyl-l-methionine umezawaea tangerina 0.011 0.011 1 PMID:30083673 -2.5.1.94 s-adenosyl-l-methionine uncultured bacterium 0.078 0.0445 2 PMID:30083673 -2.5.1.97 2,4-diacetamido-2,4,6-trideoxy-beta-l-altropyranose campylobacter jejuni 0.65 0.65 1 PMID:16120604 -2.6.1.1 2-methoxyphenylpyruvate escherichia coli 1.44 1.44 1 * -2.6.1.1 2-oxo-4-phenyl-butanoic acid escherichia coli 0.35 0.35 1 PMID:15801779 -2.6.1.1 2-oxoglutarate arabidopsis thaliana 217.0 190.5 4 PMID:29405514;PMID:9535706 -2.6.1.1 2-oxoglutarate bacillus subtilis 27.0 27.0 1 PMID:21332942 -2.6.1.1 2-oxoglutarate gallus gallus 187.0 138.5 2 PMID:9675237 -2.6.1.1 2-oxoglutarate geobacillus thermopakistaniensis 36.83 36.83 1 PMID:32738436 -2.6.1.1 2-oxoglutarate ovis aries 322.0 322.0 1 PMID:4204952 -2.6.1.1 2-oxoglutarate thermus thermophilus 120.0 120.0 1 PMID:9792664 -2.6.1.1 3,4-dimethoxyphenylpyruvate escherichia coli 1.81 1.81 1 * -2.6.1.1 3-methoxyphenylpyruvate escherichia coli 1.55 1.55 1 * -2.6.1.1 4-methoxyphenylpyruvate escherichia coli 1.77 1.77 1 * -2.6.1.1 kynurenine mycobacterium tuberculosis 198.0 198.0 1 PMID:32327655 -2.6.1.1 l-aspartate advenella mimigardefordensis 19.66 19.66 1 PMID:28193330 -2.6.1.1 l-aspartate arabidopsis thaliana 9.33 9.33 1 PMID:29405514 -2.6.1.1 l-aspartate bacillus subtilis 30.0 30.0 1 PMID:21332942 -2.6.1.1 l-aspartate bubalus bubalis 352.0 352.0 1 * -2.6.1.1 l-aspartate escherichia coli 530.0 259.0 3 PMID:11967363;PMID:22138634;PMID:28193330 -2.6.1.1 l-aspartate gallus gallus 187.0 138.5 2 PMID:9675237 -2.6.1.1 l-aspartate geobacillus thermopakistaniensis 4170.0 4170.0 1 PMID:32738436 -2.6.1.1 l-aspartate mycobacterium tuberculosis 136.0 136.0 1 PMID:32327655 -2.6.1.1 l-aspartate ovis aries 322.0 322.0 1 PMID:4204952 -2.6.1.1 l-aspartate phormidium lapideum 187.0 187.0 1 PMID:12723595 -2.6.1.1 l-aspartate thermus thermophilus 120.0 120.0 1 PMID:9792664 -2.6.1.1 l-aspartate triticum aestivum 103.8 47.75 6 * -2.6.1.1 l-cysteine advenella mimigardefordensis 43.85 43.85 1 PMID:28193330 -2.6.1.1 l-cysteine escherichia coli 40.64 40.64 1 PMID:28193330 -2.6.1.1 l-glutamate bacillus subtilis 14.0 14.0 1 PMID:21332942 -2.6.1.1 l-glutamate escherichia coli 670.0 670.0 1 PMID:22138634 -2.6.1.1 l-glutamate phormidium lapideum 101.0 101.0 1 PMID:12723595 -2.6.1.1 l-lys escherichia coli 0.305 0.305 1 PMID:15801779 -2.6.1.1 oxaloacetate arabidopsis thaliana 574.0 319.0 3 PMID:9535706 -2.6.1.1 oxaloacetate bacillus subtilis 22.0 22.0 1 PMID:21332942 -2.6.1.1 oxaloacetate sinorhizobium meliloti 205.0 205.0 1 PMID:24302739 -2.6.1.1 phenylpyruvate escherichia coli 2.99 2.99 1 * -2.6.1.102 gdp-4-dehydro-3,6-dideoxy-alpha-d-mannose caulobacter vibrioides 0.015 0.015 1 PMID:18795799 -2.6.1.102 gdp-4-dehydro-6-deoxy-alpha-d-mannose caulobacter vibrioides 2.7 2.7 2 PMID:18795799;PMID:19402712 -2.6.1.11 l-ornithine salmonella enterica subsp. enterica serovar typhimurium 0.82 0.82 1 PMID:17680699 -2.6.1.11 n2-acetyl-l-ornithine salmonella enterica subsp. enterica serovar typhimurium 1.55 1.55 1 PMID:17680699 -2.6.1.111 (3s)-3-aminobutanoyl-coa candidatus cloacimonas acidaminovorans 1.8 1.8 1 PMID:21826218 -2.6.1.111 2-oxoglutarate candidatus cloacimonas acidaminovorans 1.8 1.8 1 PMID:21826218 -2.6.1.111 pyruvate candidatus cloacimonas acidaminovorans 0.4 0.4 1 PMID:21826218 -2.6.1.116 (s)-1-phenylethan-1-amine chromobacterium violaceum 2.3 2.3 1 PMID:31162815 -2.6.1.116 (s)-1-phenylethan-1-amine pseudomonas jessenii 1.1 1.1 1 PMID:31162815 -2.6.1.116 (s)-1-phenylethan-1-amine vibrio fluvialis 1.6 1.6 1 PMID:31162815 -2.6.1.116 1-aminopentane chromobacterium violaceum 1.1 1.1 1 PMID:31162815 -2.6.1.116 1-aminopentane pseudomonas jessenii 0.18 0.18 1 PMID:31162815 -2.6.1.116 1-aminopentane vibrio fluvialis 0.6 0.6 1 PMID:31162815 -2.6.1.116 2-phenylethylamine chromobacterium violaceum 0.72 0.72 1 PMID:31162815 -2.6.1.116 2-phenylethylamine pseudomonas jessenii 0.75 0.75 1 PMID:31162815 -2.6.1.116 2-phenylethylamine vibrio fluvialis 0.3 0.3 1 PMID:31162815 -2.6.1.116 3-phenylpropylamine chromobacterium violaceum 0.38 0.38 1 PMID:31162815 -2.6.1.116 3-phenylpropylamine pseudomonas jessenii 0.13 0.13 1 PMID:31162815 -2.6.1.116 3-phenylpropylamine vibrio fluvialis 0.21 0.21 1 PMID:31162815 -2.6.1.116 4-aminobutanoate chromobacterium violaceum 0.55 0.55 1 PMID:31162815 -2.6.1.116 4-aminobutanoate pseudomonas jessenii 0.26 0.26 1 PMID:31162815 -2.6.1.116 4-aminobutanoate vibrio fluvialis 0.3 0.3 1 PMID:31162815 -2.6.1.116 4-phenylbutylamine chromobacterium violaceum 0.43 0.43 1 PMID:31162815 -2.6.1.116 4-phenylbutylamine pseudomonas jessenii 0.3 0.3 1 PMID:31162815 -2.6.1.116 4-phenylbutylamine vibrio fluvialis 0.1 0.1 1 PMID:31162815 -2.6.1.116 5-aminopentanoate chromobacterium violaceum 0.35 0.35 1 PMID:31162815 -2.6.1.116 5-aminopentanoate pseudomonas jessenii 0.21 0.21 1 PMID:31162815 -2.6.1.116 5-aminopentanoate vibrio fluvialis 0.02 0.02 1 PMID:31162815 -2.6.1.116 6-aminohexanoate chromobacterium violaceum 0.95 0.95 1 PMID:31162815 -2.6.1.116 6-aminohexanoate pseudomonas jessenii 0.3 0.3 1 PMID:31162815 -2.6.1.116 6-aminohexanoate vibrio fluvialis 0.58 0.58 1 PMID:31162815 -2.6.1.116 6-oxohexanoate chromobacterium violaceum 11.0 11.0 1 PMID:31162815 -2.6.1.116 6-oxohexanoate pseudomonas jessenii 5.4 5.4 1 PMID:31162815 -2.6.1.116 6-oxohexanoate vibrio fluvialis 1.8 1.8 1 PMID:31162815 -2.6.1.116 benzylamine chromobacterium violaceum 1.6 1.6 1 PMID:31162815 -2.6.1.116 benzylamine pseudomonas jessenii 0.75 0.75 1 PMID:31162815 -2.6.1.116 benzylamine vibrio fluvialis 0.74 0.74 1 PMID:31162815 -2.6.1.117 4-(methylsulfanyl)-2-oxobutanoate bacillus subtilis 2.32 2.32 1 PMID:24837359 -2.6.1.117 4-(methylsulfanyl)-2-oxobutanoate solanum lycopersicum 0.15 0.15 1 PMID:24837359 -2.6.1.117 4-(methylsulfanyl)-2-oxobutanoate zea mays 0.12 0.12 1 PMID:24837359 -2.6.1.118 n2-acetyl-l-lysine thermus thermophilus 0.8 0.8 1 PMID:11489859 -2.6.1.118 n2-acetyl-l-ornithine thermus thermophilus 1.0 1.0 1 PMID:11489859 -2.6.1.120 2-oxoglutarate ureibacillus massiliensis 5.6 5.6 1 PMID:31455636 -2.6.1.120 beta-alanine ureibacillus massiliensis 5.6 5.6 1 PMID:31455636 -2.6.1.120 pyruvate ureibacillus massiliensis 1.25 1.25 1 PMID:31455636 -2.6.1.120 taurine ureibacillus massiliensis 0.51 0.51 1 PMID:31455636 -2.6.1.123 chorismate stenotrophomonas maltophilia 0.02 0.0135 2 PMID:23230967 -2.6.1.123 l-glutamate bacillus subtilis 0.005 0.005 1 PMID:19275258 -2.6.1.123 nh3 bacillus subtilis 0.004 0.004 1 PMID:19275258 -2.6.1.127 spermidine arabidopsis thaliana 0.0065 0.00635 2 PMID:40028677 -2.6.1.13 2-oxoglutarate homo sapiens 35.7 35.7 3 PMID:28345116;PMID:30957963 -2.6.1.13 2-oxoglutarate manduca sexta 0.0333 0.0333 1 PMID:2295622 -2.6.1.13 2-oxoglutarate toxoplasma gondii 2.51 2.51 1 PMID:28126740 -2.6.1.13 acetylornithine toxoplasma gondii 4.6 4.6 1 PMID:28126740 -2.6.1.13 d-ornithine toxoplasma gondii 0.42 0.42 1 PMID:28126740 -2.6.1.13 l-ornithine homo sapiens 34.9 34.5 3 PMID:28345116;PMID:30957963 -2.6.1.13 l-ornithine lathyrus oleraceus 4.3 4.3 1 PMID:20381578 -2.6.1.13 l-ornithine manduca sexta 0.0333 0.0333 1 PMID:2295622 -2.6.1.13 l-ornithine toxoplasma gondii 2.1 2.1 1 PMID:28126740 -2.6.1.15 l-glutamine mus musculus 2.67 2.67 1 PMID:28955961 -2.6.1.16 d-fructose 6-phosphate candida albicans 0.0213 0.021 5 PMID:17309446 -2.6.1.16 d-fructose 6-phosphate escherichia coli 16.9 14.4 7 PMID:17559838;PMID:20416269;PMID:24814295 -2.6.1.16 d-fructose 6-phosphate saccharomyces cerevisiae 35.5 35.5 1 PMID:22125025 -2.6.1.16 l-gamma-glutamyl-p-nitroanilide candida albicans 0.013 0.012 5 PMID:17309446 -2.6.1.16 l-gamma-glutamyl-p-nitroanilide escherichia coli 0.17 0.17 1 PMID:17559838 -2.6.1.16 l-glutamate candida albicans 12.0 12.0 1 PMID:17309446 -2.6.1.16 l-glutamate escherichia coli 9.81 9.81 1 PMID:20416269 -2.6.1.16 l-glutamine candida albicans 12.0 12.0 1 PMID:17309446 -2.6.1.16 l-glutamine escherichia coli 17.2 16.95 5 PMID:17559838;PMID:24814295 -2.6.1.16 l-glutamine saccharomyces cerevisiae 35.5 35.5 1 PMID:22125025 -2.6.1.17 prephenate streptomyces avermitilis 24.0 24.0 1 PMID:24302739 -2.6.1.19 1h-tetrazole-5-butanamine sus scrofa 0.69 0.69 1 PMID:16263300 -2.6.1.19 1h-tetrazole-5-ethanamine sus scrofa 0.26 0.26 1 PMID:16263300 -2.6.1.19 1h-tetrazole-5-propanamine sus scrofa 0.48 0.48 1 PMID:16263300 -2.6.1.19 2-oxoglutarate corynebacterium glutamicum 0.34 0.34 1 * -2.6.1.19 4-(aminomethyl)-1h-pyrrole-2-carboxylic acid sus scrofa 5.6e-05 5.6e-05 1 PMID:22944334 -2.6.1.19 4-(aminomethyl)furan-2-carboxylic acid sus scrofa 3.83e-05 3.83e-05 1 PMID:22944334 -2.6.1.19 4-(aminomethyl)furan-3-carboxylic acid sus scrofa 1.38e-05 1.38e-05 1 PMID:22944334 -2.6.1.19 4-(aminomethyl)thiophene-2-carboxylic acid sus scrofa 8.6e-05 8.6e-05 1 PMID:22944334 -2.6.1.19 4-aminobutanoate arabidopsis thaliana 10.6 8.75 2 PMID:19264755 -2.6.1.19 4-aminobutanoate corynebacterium glutamicum 3.77 3.77 1 * -2.6.1.19 4-aminobutanoate escherichia coli 47.4 47.4 1 PMID:15723541 -2.6.1.19 4-aminobutanoate malus domestica 2.7 1.8 4 * -2.6.1.19 4-aminobutanoate ovis aries 13.2 13.2 1 PMID:3355498 -2.6.1.19 4-aminobutanoate sus scrofa 0.817 0.81 3 PMID:16263300;PMID:22944334 -2.6.1.19 4-oxobutanoate arabidopsis thaliana 10.8 10.8 1 PMID:19264755 -2.6.1.19 5-(aminomethyl)-1h-pyrrole-2-carboxylic acid sus scrofa 2.5e-05 2.5e-05 1 PMID:22944334 -2.6.1.19 5-(aminomethyl)furan-2-carboxylic acid sus scrofa 0.00056 0.00056 1 PMID:22944334 -2.6.1.19 5-(aminomethyl)thiophene-2-carboxylic acid sus scrofa 0.00016 0.00016 1 PMID:22944334 -2.6.1.19 glyoxylate arabidopsis thaliana 9.7 9.7 1 PMID:19264755 -2.6.1.19 glyoxylate malus domestica 2.6 1.67 2 * -2.6.1.19 l-alanine arabidopsis thaliana 15.4 15.4 1 PMID:19264755 -2.6.1.19 pyruvate arabidopsis thaliana 10.6 10.6 1 PMID:19264755 -2.6.1.19 pyruvate malus domestica 2.7 1.75 2 * -2.6.1.19 tetrazole-5-butanamine sus scrofa 0.693 0.693 1 PMID:16263300 -2.6.1.19 tetrazole-5-ethanamine sus scrofa 0.265 0.265 1 PMID:16263300 -2.6.1.19 tetrazole-5-propanamine sus scrofa 0.477 0.477 1 PMID:16263300 -2.6.1.2 2-oxoglutarate halalkalibacterium halodurans 1.25 1.25 1 PMID:22750542 -2.6.1.2 2-oxoglutarate hordeum vulgare 12.11 12.11 1 PMID:22750542 -2.6.1.2 2-oxoglutarate oryza sativa 4.98 4.98 1 PMID:22750542 -2.6.1.2 2-oxoglutarate pseudomonas putida 0.08 0.08 1 PMID:22750542 -2.6.1.2 2-oxoglutarate rhodopseudomonas palustris 0.38 0.38 1 PMID:22750542 -2.6.1.2 2-oxoglutarate saccharomyces cerevisiae 6.09 6.09 1 PMID:22750542 -2.6.1.2 2-oxoglutarate triticum aestivum 170.0 152.45 2 PMID:22863564 -2.6.1.2 2-oxoglutarate zea mays 5.49 2.91 2 PMID:22750542 -2.6.1.2 l-alanine halalkalibacterium halodurans 1.25 1.25 1 PMID:22750542 -2.6.1.2 l-alanine hordeum vulgare 12.11 12.11 1 PMID:22750542 -2.6.1.2 l-alanine kluyveromyces lactis 203.0 203.0 1 PMID:28694796 -2.6.1.2 l-alanine lachancea kluyveri 355.0 355.0 1 PMID:28694796 -2.6.1.2 l-alanine oryza sativa 4.98 4.98 1 PMID:22750542 -2.6.1.2 l-alanine pseudomonas putida 0.08 0.08 1 PMID:22750542 -2.6.1.2 l-alanine rattus norvegicus 17.1 17.1 1 * -2.6.1.2 l-alanine rhodopseudomonas palustris 0.38 0.38 1 PMID:22750542 -2.6.1.2 l-alanine saccharomyces cerevisiae 698.0 352.045 2 PMID:22750542;PMID:29867852 -2.6.1.2 l-alanine triticum aestivum 170.0 152.45 2 PMID:22863564 -2.6.1.2 l-alanine zea mays 5.49 2.91 2 PMID:22750542 -2.6.1.2 l-glutamate halalkalibacterium halodurans 2.8 2.8 1 PMID:22750542 -2.6.1.2 l-glutamate hordeum vulgare 25.62 25.62 1 PMID:22750542 -2.6.1.2 l-glutamate oryza sativa 6.86 6.86 1 PMID:22750542 -2.6.1.2 l-glutamate pseudomonas putida 0.17 0.17 1 PMID:22750542 -2.6.1.2 l-glutamate rhodopseudomonas palustris 3.06 3.06 1 PMID:22750542 -2.6.1.2 l-glutamate saccharomyces cerevisiae 8.64 8.64 1 PMID:22750542 -2.6.1.2 l-glutamate triticum aestivum 136.0 131.85 2 PMID:22863564 -2.6.1.2 l-glutamate zea mays 6.56 3.6149999999999998 2 PMID:22750542 -2.6.1.2 pyruvate halalkalibacterium halodurans 2.8 2.8 1 PMID:22750542 -2.6.1.2 pyruvate hordeum vulgare 25.62 25.62 1 PMID:22750542 -2.6.1.2 pyruvate oryza sativa 6.86 6.86 1 PMID:22750542 -2.6.1.2 pyruvate pseudomonas putida 0.17 0.17 1 PMID:22750542 -2.6.1.2 pyruvate rhodopseudomonas palustris 3.06 3.06 1 PMID:22750542 -2.6.1.2 pyruvate saccharomyces cerevisiae 8.64 8.64 1 PMID:22750542 -2.6.1.2 pyruvate triticum aestivum 136.0 131.85 2 PMID:22863564 -2.6.1.2 pyruvate zea mays 6.56 3.6149999999999998 2 PMID:22750542 -2.6.1.21 2-oxoglutarate bacillus sp. (in: firmicutes) 260.0 260.0 1 PMID:9792912 -2.6.1.21 d-alanine bacillus sp. (in: firmicutes) 340.0 280.0 3 PMID:7592528;PMID:8977094;PMID:9792912 -2.6.1.26 3,5-diiodo-l-tyrosine oryctolagus cuniculus 6.6 3.8499999999999996 2 PMID:4686924 -2.6.1.26 3,5-dinitro-l-tyrosine oryctolagus cuniculus 39.9 39.9 1 PMID:4686924 -2.6.1.26 3-iodo-l-tyrosine oryctolagus cuniculus 3.68 3.68 1 PMID:4686924 -2.6.1.26 l-thyroxine oryctolagus cuniculus 0.0233 0.0233 1 PMID:4686924 -2.6.1.26 l-triiodothyronine oryctolagus cuniculus 0.0317 0.0317 1 PMID:4686924 -2.6.1.28 l-tryptophan aspergillus nidulans 19.3 9.6516 2 PMID:17584611;PMID:17704773 -2.6.1.28 phenylpyruvate aspergillus nidulans 9.1 9.1 1 PMID:17584611 -2.6.1.30 (s)-2-aminobutyrate mesorhizobium loti 9.0 9.0 2 PMID:16545075 -2.6.1.30 2-oxobutyrate mesorhizobium loti 24.0 24.0 2 PMID:16545075 -2.6.1.30 2-oxoglutarate mesorhizobium loti 1.9 1.9 1 * -2.6.1.30 l-alanine mesorhizobium loti 41.0 41.0 2 PMID:16545075 -2.6.1.30 l-glutamate mesorhizobium loti 1.5 1.5 1 * -2.6.1.30 pyridoxal mesorhizobium loti 41.0 41.0 2 PMID:16545075 -2.6.1.30 pyridoxamine mesorhizobium loti 8.0 8.0 3 PMID:16545075;PMID:17989071 -2.6.1.30 pyruvate mesorhizobium loti 29.0 29.0 2 PMID:16545075 -2.6.1.33 dtdp-4-dehydro-6-deoxy-d-glucose escherichia coli 5.66 5.66 1 PMID:17905981 -2.6.1.33 dtdp-4-dehydro-6-deoxy-d-glucose shigella dysenteriae 0.74 0.74 1 PMID:17905981 -2.6.1.34 udp-2-acetamido-2,6-dideoxy-alpha-d-xylo-4-hexulose campylobacter jejuni subsp. jejuni 2.4 2.4 1 PMID:16286454 -2.6.1.36 2-oxoglutarate mycobacterium tuberculosis 1.43 1.43 1 PMID:26003725 -2.6.1.36 l-lysine mycobacterium tuberculosis 0.92 0.9185000000000001 2 PMID:16950391;PMID:26003725 -2.6.1.37 (2-aminoethyl)phosphonate salmonella enterica 7.4 7.4 1 PMID:12107130 -2.6.1.37 2-phosphonoacetaldehyde salmonella enterica 9.3 9.3 1 PMID:12107130 -2.6.1.37 d-alanine salmonella enterica 0.04 0.04 1 PMID:12107130 -2.6.1.37 l-alanine salmonella enterica 9.3 9.3 1 PMID:12107130 -2.6.1.39 2-oxo-3-methylvalerate thermus thermophilus 3.5 3.5 1 PMID:15256574 -2.6.1.39 2-oxoadipate thermus thermophilus 22.3 22.3 1 PMID:15256574 -2.6.1.39 2-oxoisocaproate thermus thermophilus 17.8 17.8 1 PMID:15256574 -2.6.1.39 2-oxoisovalerate thermus thermophilus 2.1 2.1 1 PMID:15256574 -2.6.1.39 l-2-aminoadipate saccharomyces cerevisiae 18.4 18.4 1 PMID:21982920 -2.6.1.39 l-2-aminoadipate thermus thermophilus 6.7 6.7 1 PMID:19632206 -2.6.1.39 l-glutamate saccharomyces cerevisiae 12.8 12.8 1 PMID:21982920 -2.6.1.39 l-glutamate thermus thermophilus 16.0 16.0 1 PMID:19632206 -2.6.1.39 l-leucine thermus thermophilus 5.1 5.1 1 PMID:19632206 -2.6.1.39 l-phenylalanine saccharomyces cerevisiae 8.3 8.3 1 PMID:21982920 -2.6.1.39 l-tyrosine saccharomyces cerevisiae 12.3 12.3 1 PMID:21982920 -2.6.1.4 glyoxylate rhodopseudomonas palustris 48.2 48.2 1 PMID:12784618 -2.6.1.4 l-alanine oryza sativa japonica group 140.6 136.75 2 * -2.6.1.4 l-glutamate oryza sativa japonica group 144.9 144.9 1 * -2.6.1.4 l-glutamate rhodopseudomonas palustris 46.8 46.8 1 PMID:12784618 -2.6.1.42 (r)-1-phenylethylamine thermobaculum terrenum 0.2 0.2 1 PMID:29453991 -2.6.1.42 2-(3-hydroxy-1-adamantyl)-2-oxoethanoic acid enterobacter sp. 2.9 2.9 1 * -2.6.1.42 2-(3-hydroxy-1-adamantyl)-2-oxoethanoic acid escherichia coli 4.11 4.11 1 * -2.6.1.42 2-oxo-3-methylvalerate thermococcus sp. 360.0 360.0 1 PMID:24687296 -2.6.1.42 2-oxobutanoate thermococcus sp. 250.0 250.0 1 PMID:24687296 -2.6.1.42 2-oxobutyrate escherichia coli 3.37 3.37 1 PMID:29523060 -2.6.1.42 2-oxocaproate thermococcus sp. 91.0 91.0 1 PMID:24687296 -2.6.1.42 2-oxoglutarate homo sapiens 340.0 340.0 1 PMID:17050531 -2.6.1.42 2-oxoglutarate thermococcus sp. 700.0 700.0 1 PMID:24687296 -2.6.1.42 2-oxohexanoate escherichia coli 23.1 11.66 2 PMID:24206068;PMID:29523060 -2.6.1.42 2-oxoisocaproate escherichia coli 24.7 24.7 1 PMID:24206068 -2.6.1.42 2-oxoisocaproate thermococcus sp. 270.0 270.0 1 PMID:24687296 -2.6.1.42 2-oxoisovalerate escherichia coli 10.5 10.5 1 PMID:24206068 -2.6.1.42 2-oxoisovalerate thermococcus sp. 270.0 270.0 1 PMID:24687296 -2.6.1.42 2-oxovalerate escherichia coli 25.9 13.25 2 PMID:24206068;PMID:29523060 -2.6.1.42 2-oxovalerate thermococcus sp. 190.0 190.0 1 PMID:24687296 -2.6.1.42 3-methyl-2-oxobutanoate escherichia coli 0.2 0.2 1 PMID:29523060 -2.6.1.42 3-methyl-2-oxobutanoic acid solanum lycopersicum 109.8 46.5 7 PMID:20435740;PMID:22226341 -2.6.1.42 3-methyl-2-oxobutanoic acid solanum pennellii 11.7 11.7 1 PMID:22226341 -2.6.1.42 3-methyl-2-oxobutyric acid enterobacter sp. 12.45 12.45 1 * -2.6.1.42 3-methyl-2-oxobutyric acid escherichia coli 16.84 16.84 1 * -2.6.1.42 3-methyl-2-oxopentanoate escherichia coli 23.0 11.535 2 PMID:24206068;PMID:29523060 -2.6.1.42 3-methyl-2-oxopentanoic acid solanum lycopersicum 83.9 23.6 7 PMID:20435740;PMID:22226341 -2.6.1.42 3-methyl-2-oxopentanoic acid solanum pennellii 84.8 84.8 1 PMID:22226341 -2.6.1.42 3-methyl-2-oxovaleric acid enterobacter sp. 12.15 12.15 1 * -2.6.1.42 3-methyl-2-oxovaleric acid escherichia coli 13.75 13.75 1 * -2.6.1.42 4,4-dimethyl-2-oxopentanoate escherichia coli 12.4 12.4 1 PMID:24206068 -2.6.1.42 4,4-dimethyl-2-oxovalerate escherichia coli 0.08 0.08 1 PMID:29523060 -2.6.1.42 4-methyl-2-oxopentanoate escherichia coli 0.08 0.08 1 PMID:29523060 -2.6.1.42 4-methyl-2-oxopentanoate synechocystis sp. 70.0 70.0 1 PMID:24302739 -2.6.1.42 4-methyl-2-oxopentanoate thermoproteus uzoniensis 3.0 3.0 1 PMID:27523731 -2.6.1.42 4-methyl-2-oxopentanoic acid solanum lycopersicum 173.8 35.0 7 PMID:20435740;PMID:22226341 -2.6.1.42 4-methyl-2-oxopentanoic acid solanum pennellii 16.3 16.3 1 PMID:22226341 -2.6.1.42 4-methyl-2-oxovaleric acid enterobacter sp. 17.32 17.32 1 * -2.6.1.42 4-methyl-2-oxovaleric acid escherichia coli 6.61 6.61 1 * -2.6.1.42 dl-2-aminoheptanoate thermococcus sp. 27.0 27.0 1 PMID:24687296 -2.6.1.42 dl-2-aminooctanoate thermococcus sp. 81.0 81.0 1 PMID:24687296 -2.6.1.42 glyoxylate homo sapiens 42.0 29.0 2 * -2.6.1.42 l-2-aminobutanoate thermococcus sp. 25.0 25.0 1 PMID:24687296 -2.6.1.42 l-alanine homo sapiens 50.0 33.5 2 * -2.6.1.42 l-alanine thermoproteus uzoniensis 2.7 2.7 1 PMID:27523731 -2.6.1.42 l-glutamate homo sapiens 1075.0 682.5 2 PMID:17050531;PMID:18419134 -2.6.1.42 l-glutamate thermococcus sp. 150.0 150.0 1 PMID:24687296 -2.6.1.42 l-isoleucine escherichia coli 48.0 48.0 2 PMID:10989422;PMID:29523060 -2.6.1.42 l-isoleucine haliangium ochraceum 0.24 0.24 1 PMID:30902765 -2.6.1.42 l-isoleucine homo sapiens 1075.0 723.0 2 PMID:17050531;PMID:18419134 -2.6.1.42 l-isoleucine solanum lycopersicum 174.0 20.0 7 PMID:20435740;PMID:22226341 -2.6.1.42 l-isoleucine solanum pennellii 69.9 58.2 2 PMID:20435740;PMID:22226341 -2.6.1.42 l-isoleucine thermococcus sp. 51.0 51.0 1 PMID:24687296 -2.6.1.42 l-leucine escherichia coli 78.0 63.0 2 PMID:10989422;PMID:29523060 -2.6.1.42 l-leucine haliangium ochraceum 0.95 0.95 1 PMID:30902765 -2.6.1.42 l-leucine homo sapiens 898.0 617.5 2 PMID:17050531;PMID:18419134 -2.6.1.42 l-leucine solanum lycopersicum 121.0 17.9 7 PMID:20435740;PMID:22226341 -2.6.1.42 l-leucine solanum pennellii 80.2 60.5 2 PMID:20435740;PMID:22226341 -2.6.1.42 l-leucine thermococcus sp. 110.0 110.0 1 PMID:24687296 -2.6.1.42 l-leucine thermoproteus uzoniensis 1.31 1.31 1 PMID:27523731 -2.6.1.42 l-methionine escherichia coli 17.0 17.0 1 PMID:10989422 -2.6.1.42 l-norleucine thermococcus sp. 260.0 260.0 1 PMID:24687296 -2.6.1.42 l-norvaline haliangium ochraceum 0.19 0.19 1 PMID:30902765 -2.6.1.42 l-norvaline thermococcus sp. 86.0 86.0 1 PMID:24687296 -2.6.1.42 l-norvaline vulcanisaeta moutnovskia 2.07 2.07 1 PMID:27871372 -2.6.1.42 l-ornithine vulcanisaeta moutnovskia 2.44 2.44 1 PMID:27871372 -2.6.1.42 l-phenylalanine escherichia coli 2.9 2.9 1 PMID:10989422 -2.6.1.42 l-phenylalanine thermococcus sp. 80.0 80.0 1 PMID:24687296 -2.6.1.42 l-tryptophan escherichia coli 3.7 3.7 1 PMID:10989422 -2.6.1.42 l-tyrosine escherichia coli 2.2 2.2 1 PMID:10989422 -2.6.1.42 l-valine escherichia coli 19.0 19.0 1 PMID:10989422 -2.6.1.42 l-valine haliangium ochraceum 0.29 0.29 1 PMID:30902765 -2.6.1.42 l-valine homo sapiens 1236.0 756.5 2 PMID:17050531;PMID:18419134 -2.6.1.42 l-valine solanum lycopersicum 123.0 28.1 7 PMID:20435740;PMID:22226341 -2.6.1.42 l-valine solanum pennellii 55.0 47.05 2 PMID:20435740;PMID:22226341 -2.6.1.42 l-valine thermococcus sp. 31.0 31.0 1 PMID:24687296 -2.6.1.42 l-valine vulcanisaeta moutnovskia 2.1 2.1 1 PMID:27871372 -2.6.1.42 phenylpyruvate thermococcus sp. 52.0 52.0 1 PMID:24687296 -2.6.1.42 pyruvate escherichia coli 56.0 56.0 1 PMID:29523060 -2.6.1.42 pyruvate thermoproteus uzoniensis 1.78 1.78 1 PMID:27523731 -2.6.1.42 trimethylpyruvate enterobacter sp. 2.59 2.59 1 * -2.6.1.42 trimethylpyruvate escherichia coli 2.2 1.175 2 PMID:29523060 -2.6.1.44 3-hydroxykynurenine aedes aegypti 20.0 20.0 1 PMID:16681462 -2.6.1.44 glycine homo sapiens 0.33 0.33 2 PMID:17696873 -2.6.1.44 glyoxylate aedes aegypti 16.0 16.0 1 PMID:12220660 -2.6.1.44 glyoxylate drosophila melanogaster 113.0 113.0 1 PMID:12220660 -2.6.1.44 glyoxylate homo sapiens 45.0 39.0 15 PMID:17696873;PMID:19155213;PMID:21176891;PMID:27720751 -2.6.1.44 kynurenine aedes aegypti 12.0 12.0 1 PMID:16681462 -2.6.1.44 l-alanine aedes aegypti 117.0 34.2 3 PMID:12220660;PMID:16681462 -2.6.1.44 l-alanine drosophila melanogaster 131.0 131.0 1 PMID:12220660 -2.6.1.44 l-alanine homo sapiens 45.0 34.3 16 PMID:17696873;PMID:19155213;PMID:21176891;PMID:23589421;PMID:27720751 -2.6.1.44 l-cysteine homo sapiens 0.22 0.22 1 PMID:18492492 -2.6.1.44 pyruvate homo sapiens 0.36 0.36 2 PMID:17696873 -2.6.1.45 l-alanine arabidopsis thaliana 2.86 2.86 1 PMID:18235971 -2.6.1.45 l-alanine oryza sativa japonica group 8.56 8.56 1 * -2.6.1.45 l-serine arabidopsis thaliana 6.4 6.4 1 PMID:18235971 -2.6.1.45 l-serine oryza sativa japonica group 19.82 10.925 2 * -2.6.1.46 2-oxoglutarate pseudomonas aeruginosa 1.39 1.39 1 PMID:15317763 -2.6.1.46 pyruvate pseudomonas aeruginosa 1.39 1.39 1 PMID:15317763 -2.6.1.5 (s)-beta-phenylalanine variovorax paradoxus 11.8 11.8 1 PMID:23087034 -2.6.1.5 2-oxoglutarate arabidopsis thaliana 48.0 24.265 2 PMID:27726859 -2.6.1.5 2-oxoglutarate homo sapiens 0.25 0.25 1 PMID:16640556 -2.6.1.5 2-oxoglutarate mus musculus 25.66 25.66 1 PMID:21153519 -2.6.1.5 2-oxoglutarate papaver somniferum 0.22 0.22 1 PMID:21949209 -2.6.1.5 2-oxoglutarate petunia x hybrida 0.92 0.92 1 PMID:24270997 -2.6.1.5 2-oxoglutarate prunella vulgaris 0.63 0.63 1 PMID:28687763 -2.6.1.5 2-oxoglutarate rattus norvegicus 566.0 566.0 1 PMID:12717026 -2.6.1.5 2-oxoglutarate trypanosoma cruzi 21.8 21.8 1 PMID:12717026 -2.6.1.5 2-oxoglutarate variovorax paradoxus 10.6 10.6 1 PMID:23087034 -2.6.1.5 2-oxohexanoate mus musculus 1.83 1.83 1 PMID:21153519 -2.6.1.5 2-oxoisocaproate trypanosoma cruzi 34.0 34.0 1 PMID:12717026 -2.6.1.5 4-hydroxyphenylpyruvate arabidopsis thaliana 23.9 12.165 2 PMID:27726859 -2.6.1.5 4-hydroxyphenylpyruvate mus musculus 15.83 15.83 1 PMID:21153519 -2.6.1.5 4-hydroxyphenylpyruvate petunia x hybrida 0.7 0.7 1 PMID:24270997 -2.6.1.5 4-hydroxyphenylpyruvate prunella vulgaris 0.121 0.121 1 PMID:28687763 -2.6.1.5 4-methylthio-2-oxobutanoate arabidopsis thaliana 20.1 9.6 4 PMID:27726859 -2.6.1.5 l-alanine trypanosoma cruzi 23.5 23.5 1 PMID:12717026 -2.6.1.5 l-glutamate homo sapiens 69.0 36.4 2 PMID:16640556 -2.6.1.5 l-glutamate mus musculus 9.33 9.33 1 PMID:21153519 -2.6.1.5 l-glutamate petunia x hybrida 0.44 0.44 1 PMID:24270997 -2.6.1.5 l-glutamate rattus norvegicus 210.0 210.0 1 PMID:12717026 -2.6.1.5 l-methionine arabidopsis thaliana 26.6 13.565000000000001 2 PMID:27726859 -2.6.1.5 l-phenylalanine arabidopsis thaliana 31.6 16.055 2 PMID:27726859 -2.6.1.5 l-phenylalanine mus musculus 15.33 15.33 1 PMID:21153519 -2.6.1.5 l-phenylalanine papaver somniferum 0.08 0.08 1 PMID:21949209 -2.6.1.5 l-phenylalanine petunia x hybrida 0.44 0.305 2 PMID:24270997 -2.6.1.5 l-phenylalanine prunella vulgaris 1.55 1.55 1 PMID:28687763 -2.6.1.5 l-tryptophan papaver somniferum 0.36 0.36 1 PMID:21949209 -2.6.1.5 l-tryptophan prunella vulgaris 1.05 1.05 1 PMID:28687763 -2.6.1.5 l-tyrosine arabidopsis thaliana 57.3 29.025 2 PMID:27726859 -2.6.1.5 l-tyrosine escherichia coli 39.0 30.650000000000002 4 PMID:14767072 -2.6.1.5 l-tyrosine homo sapiens 83.0 42.0 2 PMID:16640556 -2.6.1.5 l-tyrosine mus musculus 19.33 19.33 1 PMID:21153519 -2.6.1.5 l-tyrosine papaver somniferum 0.24 0.24 1 PMID:21949209 -2.6.1.5 l-tyrosine petunia x hybrida 1.48 1.48 1 PMID:24270997 -2.6.1.5 l-tyrosine prunella vulgaris 1.19 1.19 1 PMID:28687763 -2.6.1.5 l-tyrosine rattus norvegicus 576.0 576.0 1 PMID:12717026 -2.6.1.5 l-tyrosine trypanosoma cruzi 44.6 44.6 1 PMID:12717026 -2.6.1.5 oxaloacetate arabidopsis thaliana 0.56 0.56 1 PMID:27726859 -2.6.1.5 oxaloacetate papaver somniferum 0.37 0.37 1 PMID:21949209 -2.6.1.5 oxaloacetate prunella vulgaris 0.73 0.42 2 PMID:28687763 -2.6.1.5 p-hydroxyphenylpyruvate homo sapiens 1.2 1.2 1 PMID:16640556 -2.6.1.5 p-hydroxyphenylpyruvate rattus norvegicus 165.0 165.0 1 PMID:12717026 -2.6.1.5 phenylpyruvate arabidopsis thaliana 30.2 12.485 4 PMID:27726859 -2.6.1.5 phenylpyruvate mus musculus 2.66 2.66 1 PMID:21153519 -2.6.1.5 phenylpyruvate petunia x hybrida 1.46 1.325 2 PMID:24270997 -2.6.1.5 phenylpyruvate prunella vulgaris 0.3 0.22499999999999998 2 PMID:28687763 -2.6.1.5 pyruvate papaver somniferum 0.34 0.34 1 PMID:21949209 -2.6.1.5 pyruvate prunella vulgaris 0.89 0.89 1 PMID:28687763 -2.6.1.5 pyruvate trypanosoma cruzi 47.4 47.4 1 PMID:12717026 -2.6.1.51 alanine drosophila melanogaster 131.0 131.0 1 PMID:12220660 -2.6.1.51 glyoxylate drosophila melanogaster 113.0 113.0 1 PMID:12220660 -2.6.1.52 3-o-phospho-l-serine escherichia coli 0.63 0.51 2 PMID:8706854 -2.6.1.52 3-phosphonooxypyruvate escherichia coli 1.75 1.54 2 PMID:8706854 -2.6.1.52 4-(phosphonooxy)-l-threonine escherichia coli 0.15 0.11499999999999999 2 PMID:8706854 -2.6.1.52 l-glutamate synechocystis sp. 2.49 2.49 1 PMID:25701735 -2.6.1.52 o-phospho-l-serine entamoeba histolytica 0.625 0.625 1 PMID:30959130 -2.6.1.55 2-oxoglutarate bifidobacterium catenulatum subsp. kashiwanohense 3.7 3.7 1 PMID:31088892 -2.6.1.55 taurine bifidobacterium catenulatum subsp. kashiwanohense 3.7 3.7 1 PMID:31088892 -2.6.1.57 2-oxoglutarate aspergillus fumigatus 12.5 12.5 1 PMID:30547035 -2.6.1.57 2-oxoglutarate escherichia coli 278.0 278.0 1 PMID:3298975 -2.6.1.57 2-oxoglutarate pyrococcus furiosus 225.0 225.0 1 PMID:7873596;PMID:8125113 -2.6.1.57 alpha-aminoadipate aspergillus fumigatus 13.2 7.85 2 PMID:30547035 -2.6.1.57 l-aspartate escherichia coli 290.0 215.0 2 PMID:8218300;PMID:8639626 -2.6.1.57 l-aspartate paracoccus denitrificans 16.9 16.9 1 PMID:28193330 -2.6.1.57 l-cysteine paracoccus denitrificans 16.89 16.89 1 PMID:28193330 -2.6.1.57 l-glutamate aspergillus fumigatus 10.3 10.3 1 PMID:30547035 -2.6.1.57 l-kynurenine aspergillus fumigatus 4.1 4.1 1 PMID:30547035 -2.6.1.57 l-phenylalanine aspergillus fumigatus 7.4 7.4 1 PMID:30547035 -2.6.1.57 l-phenylalanine escherichia coli 1200.0 250.0 3 PMID:3298975;PMID:8218300;PMID:8639626 -2.6.1.57 l-phenylalanine pyrococcus furiosus 253.0 253.0 2 PMID:7873596;PMID:8125113 -2.6.1.57 l-tryptophan aspergillus fumigatus 3.0 3.0 1 PMID:30547035 -2.6.1.57 l-tryptophan escherichia coli 350.0 250.0 3 PMID:3298975;PMID:8218300;PMID:8639626 -2.6.1.57 l-tryptophan pyrococcus furiosus 62.0 62.0 2 PMID:7873596;PMID:8125113 -2.6.1.57 l-tyrosine aspergillus fumigatus 4.0 4.0 1 PMID:30547035 -2.6.1.57 l-tyrosine escherichia coli 500.0 333.0 3 PMID:3298975;PMID:8218300;PMID:8639626 -2.6.1.57 l-tyrosine pyrococcus furiosus 72.0 72.0 2 PMID:7873596;PMID:8125113 -2.6.1.57 oxaloacetate escherichia coli 500.0 500.0 1 PMID:3298975 -2.6.1.59 dtdp-4-dehydro-6-deoxy-d-glucose escherichia coli 0.38 0.38 1 PMID:15271350 -2.6.1.62 (s)-(-)-1-phenylethylamine psychrobacter cryohalolentis 0.16 0.10250000000000001 2 PMID:30178202 -2.6.1.62 2,3-butanedione psychrobacter cryohalolentis 0.026 0.026 1 PMID:30178202 -2.6.1.62 8-amino-7-oxononanoate escherichia coli 0.8 0.5365 4 PMID:1092682;PMID:12379100;PMID:14567709;PMID:14756557;PMID:374976 -2.6.1.62 8-amino-7-oxononanoate mycobacterium tuberculosis 1.0 1.0 1 PMID:16984394 -2.6.1.62 isobutyraldehyde psychrobacter cryohalolentis 0.25 0.25 1 PMID:30178202 -2.6.1.62 s-adenosyl-l-methionine arabidopsis thaliana 0.0012 0.0012 1 PMID:22547782 -2.6.1.62 s-adenosyl-l-methionine escherichia coli 0.13 0.05 4 PMID:14567709;PMID:14756557;PMID:16042602 -2.6.1.62 s-adenosyl-l-methionine mycobacterium tuberculosis 0.017 0.0145 2 PMID:16984394;PMID:20565114 -2.6.1.62 sinefungin mycobacterium tuberculosis 0.009 0.009 1 PMID:20565114 -2.6.1.64 2-oxoglutarate thermus thermophilus 3.1 3.1 1 PMID:14769873 -2.6.1.64 4-hydroxyphenylpyruvate thermus thermophilus 620.0 620.0 1 PMID:14769873 -2.6.1.64 4-methylsulfanyl-2-oxobutanoate thermus thermophilus 620.0 620.0 1 PMID:14769873 -2.6.1.64 indolepyruvate thermus thermophilus 480.0 480.0 1 PMID:14769873 -2.6.1.64 l-alanine thermus thermophilus 0.18 0.18 1 PMID:14769873 -2.6.1.64 l-arginine thermus thermophilus 0.12 0.12 1 PMID:14769873 -2.6.1.64 l-asparagine thermus thermophilus 0.13 0.13 1 PMID:14769873 -2.6.1.64 l-aspartate thermus thermophilus 0.016 0.016 1 PMID:14769873 -2.6.1.64 l-glutamate thermus thermophilus 0.03 0.03 1 PMID:14769873 -2.6.1.64 l-glutamine thermus thermophilus 830.0 830.0 1 PMID:14769873 -2.6.1.64 l-histidine thermus thermophilus 1.3 1.3 1 PMID:14769873 -2.6.1.64 l-kynurenine thermus thermophilus 1100.0 1100.0 1 PMID:14769873 -2.6.1.64 l-leucine thermus thermophilus 1.5 1.5 1 PMID:14769873 -2.6.1.64 l-methionine thermus thermophilus 1200.0 1200.0 1 PMID:14769873 -2.6.1.64 l-phenylalanine thermus thermophilus 590.0 590.0 1 PMID:14769873 -2.6.1.64 l-serine thermus thermophilus 1.2 1.2 1 PMID:14769873 -2.6.1.64 l-threonine thermus thermophilus 0.013 0.013 1 PMID:14769873 -2.6.1.64 l-tryptophan thermus thermophilus 990.0 990.0 1 PMID:14769873 -2.6.1.64 l-tyrosine thermus thermophilus 970.0 970.0 1 PMID:14769873 -2.6.1.64 phenylpyruvate thermus thermophilus 130.0 130.0 1 PMID:14769873 -2.6.1.64 pyruvate thermus thermophilus 15.0 15.0 1 PMID:14769873 -2.6.1.7 2-aminobutanoate aedes aegypti 317.0 317.0 1 PMID:15556614 -2.6.1.7 2-aminobutanoate homo sapiens 38.3 38.3 1 PMID:15606768 -2.6.1.7 2-oxo-4-methylthiobutyrate haemaphysalis longicornis 0.16 0.16 1 PMID:19381689 -2.6.1.7 2-oxo-4-methylthiobutyrate homo sapiens 4.27 4.27 1 PMID:18620547 -2.6.1.7 2-oxo-4-methylthiobutyrate mus musculus 0.41 0.41 1 PMID:20977429 -2.6.1.7 2-oxoadipate homo sapiens 4.84 4.84 1 PMID:18620547 -2.6.1.7 2-oxobutanoate homo sapiens 234.0 234.0 1 PMID:15606768 -2.6.1.7 2-oxobutyrate haemaphysalis longicornis 0.0018 0.0018 1 PMID:19381689 -2.6.1.7 2-oxobutyrate homo sapiens 3.49 3.49 1 PMID:18620547 -2.6.1.7 2-oxobutyrate mus musculus 2.93 1.81 2 PMID:19029248;PMID:20977429 -2.6.1.7 2-oxocaproate homo sapiens 4.83 4.83 1 PMID:18620547 -2.6.1.7 2-oxocaproic acid mus musculus 2.59 1.5 2 PMID:19029248;PMID:20977429 -2.6.1.7 2-oxoglutarate homo sapiens 7.67 7.67 1 PMID:18620547 -2.6.1.7 2-oxoglutarate mus musculus 0.53 0.45 2 PMID:19029248;PMID:20977429 -2.6.1.7 2-oxoisocaproate homo sapiens 296.0 296.0 1 PMID:15606768 -2.6.1.7 2-oxoisocaproic acid mus musculus 0.74 0.74 1 PMID:19029248 -2.6.1.7 2-oxovalerate homo sapiens 2.66 2.66 1 PMID:18620547 -2.6.1.7 2-oxovalerate mus musculus 2.7 1.415 2 PMID:19029248;PMID:20977429 -2.6.1.7 3-hydroxykynurenine haemaphysalis longicornis 65.12 65.12 1 PMID:19381689 -2.6.1.7 3-methyl-2-oxobutanoate homo sapiens 0.92 0.92 1 PMID:18620547 -2.6.1.7 3-methyl-2-oxopentanoate homo sapiens 0.92 0.92 1 PMID:18620547 -2.6.1.7 4-methyl-2-oxopentanoate homo sapiens 2.51 2.51 1 PMID:18620547 -2.6.1.7 alpha-oxo-gamma-methiol-butyric acid mus musculus 1.02 1.02 1 PMID:19029248 -2.6.1.7 glyoxylate homo sapiens 263.0 133.32 2 PMID:15606768;PMID:18620547 -2.6.1.7 glyoxylate mus musculus 2.71 1.45 2 PMID:19029248;PMID:20977429 -2.6.1.7 hydroxyphenylpyruvate homo sapiens 0.39 0.39 1 PMID:18620547 -2.6.1.7 hydroxyphenylpyruvate mus musculus 1.48 0.945 2 PMID:19029248;PMID:20977429 -2.6.1.7 indo-3-pyruvate homo sapiens 1.49 1.49 1 PMID:18620547 -2.6.1.7 indo-3-pyruvate mus musculus 1.03 1.03 1 PMID:19029248 -2.6.1.7 indole-3-pyruvate mus musculus 0.49 0.49 1 PMID:20977429 -2.6.1.7 l-alanine aedes aegypti 1540.0 1540.0 1 PMID:15556614 -2.6.1.7 l-alanine mus musculus 1.53 1.53 1 PMID:19029248 -2.6.1.7 l-asparagine aedes aegypti 230.0 230.0 1 PMID:15556614 -2.6.1.7 l-asparagine homo sapiens 14.4 14.4 1 PMID:15606768 -2.6.1.7 l-asparagine mus musculus 2.93 2.93 1 PMID:19029248 -2.6.1.7 l-cysteine aedes aegypti 206.0 206.0 1 PMID:15556614 -2.6.1.7 l-cysteine homo sapiens 9.6 9.6 1 PMID:15606768 -2.6.1.7 l-cysteine mus musculus 1.3 1.3 1 PMID:19029248 -2.6.1.7 l-glutamine aedes aegypti 561.0 561.0 1 PMID:15556614 -2.6.1.7 l-glutamine homo sapiens 440.0 440.0 1 PMID:15606768 -2.6.1.7 l-glutamine mus musculus 2.27 2.27 1 PMID:19029248 -2.6.1.7 l-histidine aedes aegypti 168.0 168.0 1 PMID:15556614 -2.6.1.7 l-histidine homo sapiens 143.0 143.0 1 PMID:15606768 -2.6.1.7 l-histidine mus musculus 2.0 2.0 1 PMID:19029248 -2.6.1.7 l-kynurenine aedes aegypti 172.0 172.0 1 PMID:15556614 -2.6.1.7 l-kynurenine haemaphysalis longicornis 55.5 55.5 1 PMID:19381689 -2.6.1.7 l-kynurenine homo sapiens 201.0 4.6 5 PMID:15606768;PMID:18620547;PMID:21439022;PMID:26874021 -2.6.1.7 l-kynurenine mus musculus 2.3 2.3 1 PMID:19029248 -2.6.1.7 l-leucine aedes aegypti 758.0 758.0 1 PMID:15556614 -2.6.1.7 l-leucine homo sapiens 339.0 339.0 1 PMID:15606768 -2.6.1.7 l-methionine aedes aegypti 163.0 163.0 1 PMID:15556614 -2.6.1.7 l-methionine homo sapiens 215.0 215.0 1 PMID:15606768 -2.6.1.7 l-methionine mus musculus 2.43 2.43 1 PMID:19029248 -2.6.1.7 l-phenylalanine aedes aegypti 283.0 283.0 1 PMID:15556614 -2.6.1.7 l-phenylalanine homo sapiens 91.0 91.0 1 PMID:15606768 -2.6.1.7 l-phenylalanine mus musculus 2.7 2.7 1 PMID:19029248 -2.6.1.7 l-serine aedes aegypti 345.0 345.0 1 PMID:15556614 -2.6.1.7 l-serine mus musculus 2.17 2.17 1 PMID:19029248 -2.6.1.7 l-tryptophan aedes aegypti 283.0 283.0 1 PMID:15556614 -2.6.1.7 l-tryptophan homo sapiens 43.1 43.1 1 PMID:15606768 -2.6.1.7 l-tryptophan mus musculus 3.57 3.57 1 PMID:19029248 -2.6.1.7 l-tyrosine aedes aegypti 139.0 139.0 1 PMID:15556614 -2.6.1.7 l-tyrosine homo sapiens 91.0 91.0 1 PMID:15606768 -2.6.1.7 l-tyrosine mus musculus 1.03 1.03 1 PMID:19029248 -2.6.1.7 mercaptopyruvate homo sapiens 234.0 118.795 2 PMID:15606768;PMID:18620547 -2.6.1.7 mercaptopyruvate mus musculus 3.28 1.8599999999999999 2 PMID:19029248;PMID:20977429 -2.6.1.7 oxaloacetate homo sapiens 143.0 71.5325 2 PMID:15606768;PMID:18620547 -2.6.1.7 oxaloacetate mus musculus 3.68 2.0 2 PMID:19029248;PMID:20977429 -2.6.1.7 phenylpyruvate homo sapiens 110.0 57.365 2 PMID:15606768;PMID:18620547 -2.6.1.7 phenylpyruvate mus musculus 3.17 2.53 3 PMID:19029248;PMID:20977429;PMID:28955961 -2.6.1.7 pyruvate haemaphysalis longicornis 2.02 2.02 1 PMID:19381689 -2.6.1.7 pyruvate homo sapiens 29.0 14.68 2 PMID:15606768;PMID:18620547 -2.6.1.7 pyruvate mus musculus 1.87 1.12 2 PMID:19029248;PMID:20977429 -2.6.1.76 2-oxoglutarate halomonas elongata 4.5 4.5 1 PMID:26051748 -2.6.1.76 l-2,4-diaminobutanoate halomonas elongata 120.0 120.0 1 PMID:26051748 -2.6.1.78 l-aspartate arabidopsis thaliana 65.0 65.0 1 PMID:20883697 -2.6.1.78 oxaloacetate sinorhizobium meliloti 158.4 158.4 1 PMID:30771275 -2.6.1.78 oxaloacetate thermus thermophilus 32.2 32.2 1 PMID:30771275 -2.6.1.78 prephenate arabidopsis thaliana 3.83 3.83 1 PMID:29405514 -2.6.1.78 prephenate sinorhizobium meliloti 42.3 42.3 1 PMID:30771275 -2.6.1.78 prephenate thermus thermophilus 7.7 7.7 1 PMID:30771275 -2.6.1.79 l-glutamate arabidopsis thaliana 200.0 200.0 1 PMID:20883697 -2.6.1.79 prephenate sinorhizobium meliloti 43.0 43.0 1 PMID:24302739 -2.6.1.79 prephenate streptomyces avermitilis 54.0 39.0 2 PMID:24302739 -2.6.1.79 prephenate synechocystis sp. 60.0 60.0 1 PMID:24302739 -2.6.1.81 l-ornithine escherichia coli 3.5 3.5 1 PMID:23484010 -2.6.1.81 n2-acetyl-l-ornithine escherichia coli 4.7 4.7 1 PMID:23484010 -2.6.1.81 n2-succinyl-l-ornithine escherichia coli 3.0 3.0 1 PMID:23484010 -2.6.1.83 ll-2,6-diaminoheptanedioate chlamydomonas reinhardtii 16.4 16.4 1 PMID:24268540 -2.6.1.83 ll-2,6-diaminoheptanedioate leptospira interrogans 5.7 5.7 1 PMID:24268540 -2.6.1.83 ll-2,6-diaminoheptanedioate verrucomicrobium spinosum 1.6 1.03 2 PMID:24268540;PMID:32478518 -2.6.1.83 ll-diaminopimelate chlamydomonas reinhardtii 19.0 19.0 1 PMID:21633707 -2.6.1.83 ll-diaminopimelate methanococcus maripaludis 0.31 0.31 1 PMID:20418392 -2.6.1.83 tetrahydrodipicolinate chlamydomonas reinhardtii 1.1 1.1 1 PMID:21633707 -2.6.1.84 l-arginine pseudomonas aeruginosa 38.6 38.6 2 PMID:17416668 -2.6.1.84 pyruvate pseudomonas aeruginosa 38.6 38.6 1 PMID:17416668 -2.6.1.85 2-amino-2-deoxychorismate stenotrophomonas maltophilia 0.02 0.02 1 PMID:23230967 -2.6.1.85 chorismate agaricus bisporus 0.017 0.017 1 PMID:25152061 -2.6.1.85 chorismate escherichia coli 0.53 0.281 2 PMID:14982443 -2.6.1.85 chorismate pseudomonas aeruginosa 2.2 1.1800000000000002 2 PMID:23099261 -2.6.1.85 chorismate stenotrophomonas maltophilia 0.007 0.007 1 PMID:23230967 -2.6.1.85 l-glutamine agaricus bisporus 0.013 0.013 1 PMID:25152061 -2.6.1.85 l-glutamine arabidopsis thaliana 0.79 0.23 3 PMID:20851095 -2.6.1.85 l-glutamine escherichia coli 0.67 0.67 1 PMID:20170126 -2.6.1.85 nh3 arabidopsis thaliana 0.12 0.12 1 PMID:20851095 -2.6.1.86 chorismate burkholderia lata 0.01 0.01 1 PMID:21454481 -2.6.1.86 chorismate pseudomonas aeruginosa 2.2 1.1800000000000002 2 PMID:23099261 -2.6.1.9 l-histidinol phosphate corynebacterium glutamicum 1.18 1.18 1 PMID:18560156 -2.6.1.9 l-histidinol phosphate mycobacterium tuberculosis 426.0 426.0 1 PMID:26738801 -2.6.1.9 l-histidinol phosphate thermotoga maritima 0.046 0.046 1 PMID:15007066 -2.6.1.9 l-leucine corynebacterium glutamicum 3.27 3.27 1 PMID:18560156 -2.6.1.9 l-phenylalanine corynebacterium glutamicum 4.1 4.1 1 PMID:18560156 -2.6.1.9 l-phenylalanine mycobacterium tuberculosis 220.0 220.0 1 PMID:26738801 -2.6.1.9 l-phenylalanine thermotoga maritima 0.009 0.009 1 PMID:15007066 -2.6.1.9 l-tryptophan thermotoga maritima 0.014 0.014 1 PMID:15007066 -2.6.1.9 l-tyrosine mycobacterium tuberculosis 3100.0 3100.0 1 PMID:26738801 -2.6.1.9 l-tyrosine thermotoga maritima 0.043 0.043 1 PMID:15007066 -2.6.1.92 udp-2-acetamido-2,6-dideoxy-beta-l-arabino-hex-4-ulose campylobacter jejuni 0.067 0.067 1 PMID:16286454 -2.6.1.96 4-aminobutanoate arabidopsis thaliana 10.6 8.75 2 PMID:19264755 -2.6.1.96 4-aminobutanoate malus domestica 1.0 0.9199999999999999 2 * -2.6.1.96 glyoxylate arabidopsis thaliana 12.1 10.899999999999999 2 PMID:19264755 -2.6.1.96 glyoxylate malus domestica 0.74 0.74 1 * -2.6.1.96 l-alanine arabidopsis thaliana 15.4 14.75 2 PMID:19264755 -2.6.1.96 pyruvate arabidopsis thaliana 10.6 10.6 1 PMID:19264755 -2.6.1.96 pyruvate malus domestica 0.8 0.8 1 * -2.6.1.96 succinate semialdehyde arabidopsis thaliana 10.8 10.8 1 PMID:19264755 -2.6.99.3 hydroxyurea streptomyces lavendulae 11.0 11.0 2 PMID:23529730;PMID:26207937 -2.7.1.1 2-deoxy-d-glucose eimeria tenella 33.7 33.7 1 PMID:27150971 -2.7.1.1 2-deoxy-d-glucose homo sapiens 29.0 29.0 1 PMID:16768451 -2.7.1.1 atp cryptosporidium parvum 9.5 9.5 1 PMID:25216472 -2.7.1.1 atp homo sapiens 68.4 62.3 5 PMID:15677479;PMID:19459610;PMID:21569204 -2.7.1.1 atp mus musculus 53.2 53.2 1 PMID:17353190 -2.7.1.1 atp solanum chacoense 3.5 3.5 1 PMID:16376570 -2.7.1.1 atp toxoplasma gondii 3.32 3.32 1 PMID:12076625 -2.7.1.1 beta-d-glucose homo sapiens 166.0 72.1 4 PMID:22446163 -2.7.1.1 ctp solanum chacoense 1.61 1.61 1 PMID:16376570 -2.7.1.1 d-fructose cryptosporidium parvum 0.02 0.02 1 PMID:25216472 -2.7.1.1 d-fructose eimeria tenella 1.5 1.5 1 PMID:27150971 -2.7.1.1 d-fructose solanum chacoense 3.69 3.69 1 PMID:16376570 -2.7.1.1 d-glucose cryptosporidium parvum 20.5 20.5 1 PMID:25216472 -2.7.1.1 d-glucose eimeria tenella 219.0 219.0 1 PMID:27150971 -2.7.1.1 d-glucose entamoeba histolytica 284.0 239.5 2 PMID:10613700 -2.7.1.1 d-glucose homo sapiens 101.0 60.4 13 PMID:16768451;PMID:18397317;PMID:19187021;PMID:19459610;PMID:19473033;PMID:21569204;PMID:21831042;PMID:24723372 -2.7.1.1 d-glucose mus musculus 93.39 73.295 2 PMID:17353190;PMID:28063798 -2.7.1.1 d-glucose saccharomyces cerevisiae 1.67 1.365 2 PMID:12648923 -2.7.1.1 d-glucose solanum chacoense 5.01 4.154999999999999 2 PMID:16376570 -2.7.1.1 d-glucose toxoplasma gondii 3.47 3.47 1 PMID:12076625 -2.7.1.1 d-glucose trypanosoma brucei 483.3 483.3 1 PMID:17028241 -2.7.1.1 d-mannose cryptosporidium parvum 12.1 12.1 1 PMID:25216472 -2.7.1.1 d-mannose eimeria tenella 0.025 0.025 1 PMID:27150971 -2.7.1.1 d-mannose solanum chacoense 3.78 3.78 1 PMID:16376570 -2.7.1.1 gtp solanum chacoense 0.85 0.85 1 PMID:16376570 -2.7.1.1 ttp solanum chacoense 1.42 1.42 1 PMID:16376570 -2.7.1.1 utp solanum chacoense 3.02 3.02 1 PMID:16376570 -2.7.1.105 atp rattus norvegicus 0.14 0.14 1 PMID:17499765 -2.7.1.105 beta-d-fructose 6-phosphate escherichia coli 9320.0 9240.0 3 PMID:12927023;PMID:15848164 -2.7.1.105 beta-d-fructose 6-phosphate homo sapiens 0.447 0.43 3 PMID:15896703 -2.7.1.105 beta-d-fructose 6-phosphate rattus norvegicus 0.14 0.14 1 PMID:17499765 -2.7.1.105 d-fructose 6-phosphate escherichia coli 53.0 53.0 2 PMID:16866375 -2.7.1.105 mgatp2- escherichia coli 9320.0 90.0 5 PMID:12927023;PMID:15848164;PMID:16866375 -2.7.1.107 1,2-dioleoyl-sn-glycerol homo sapiens 2.43 1.2 3 PMID:17455907 -2.7.1.107 1-stearoyl-2-arachidonoyl-sn-glycerol homo sapiens 5.7 1.7 3 PMID:17455907 -2.7.1.107 1-stearoyl-2-linoleoyl-sn-glycerol homo sapiens 2.8 1.23 3 PMID:17455907 -2.7.1.107 1-stearoyl-2-oleoyl-sn-glycerol homo sapiens 2.35 2.35 1 PMID:18801368 -2.7.1.107 atp homo sapiens 23.0 8.2 3 PMID:17455907 -2.7.1.11 adp thermococcus kodakarensis 4410.0 475.0 3 PMID:31337538 -2.7.1.11 amp thermococcus kodakarensis 112.0 112.0 1 PMID:31337538 -2.7.1.11 atp dictyostelium discoideum 236.0 236.0 1 PMID:22530721 -2.7.1.11 atp escherichia coli 62.0 31.0185 2 PMID:20887711 -2.7.1.11 atp homo sapiens 357.0 357.0 1 PMID:22530721 -2.7.1.11 d-fructose 1,6-bisphosphate thermococcus kodakarensis 95.0 95.0 1 PMID:31337538 -2.7.1.11 d-fructose 6-phosphate clostridium thermosuccinogenes 41.0 41.0 1 PMID:31871051 -2.7.1.11 d-fructose 6-phosphate escherichia coli 60.0 22.6 4 PMID:11300773;PMID:21147773;PMID:31871051 -2.7.1.11 d-fructose 6-phosphate staphylococcus aureus 6.5 6.5 1 PMID:29940104 -2.7.1.11 d-fructose 6-phosphate thermococcus kodakarensis 4328.0 495.0 3 PMID:31337538 -2.7.1.11 d-glucose thermococcus kodakarensis 104.0 104.0 1 PMID:31337538 -2.7.1.11 fructose 1,6-bisphosphate geobacillus stearothermophilus 3.2 3.2 1 PMID:8136379 -2.7.1.11 fructose 6-phosphate escherichia coli 185.0 88.0 9 PMID:11300773;PMID:12767227;PMID:1429704;PMID:7575542 -2.7.1.11 fructose 6-phosphate geobacillus stearothermophilus 149.0 130.5 2 PMID:7873536;PMID:8136379 -2.7.1.11 sedoheptulose 7-phosphate escherichia coli 0.25 0.25 1 PMID:31871051 -2.7.1.113 1-(2-deoxy-beta-d-ribofuranosyl)-7-iodoisocarbostyril homo sapiens 0.007 0.007 1 PMID:15628745 -2.7.1.113 2'-deoxyguanosine homo sapiens 0.07 0.05 2 PMID:15450953;PMID:15628745 -2.7.1.113 2'deoxyguanosine bacillus subtilis 2.25 1.6099999999999999 4 PMID:11078735 -2.7.1.113 atp bacillus subtilis 1.53 1.53 1 PMID:11078735 -2.7.1.113 ctp bacillus subtilis 2.25 2.25 1 PMID:11078735 -2.7.1.113 deoxyadenosine dictyostelium discoideum 0.0047 0.0047 1 PMID:17448496 -2.7.1.113 deoxyadenosine xenopus laevis 0.3 0.3 1 PMID:27906638 -2.7.1.113 deoxycytidine xenopus laevis 0.51 0.51 1 PMID:27906638 -2.7.1.113 deoxyguanosine bacillus subtilis 2.25 1.6099999999999999 4 PMID:11078735 -2.7.1.113 deoxyguanosine dictyostelium discoideum 3.0 3.0 1 PMID:17448496 -2.7.1.113 deoxyguanosine xenopus laevis 0.11 0.11 1 PMID:27906638 -2.7.1.113 deoxythymidine xenopus laevis 0.07 0.07 1 PMID:27906638 -2.7.1.113 deoxyuridine xenopus laevis 0.02 0.02 1 PMID:27906638 -2.7.1.113 dioxolane guanosine homo sapiens 0.025 0.025 1 PMID:15450953 -2.7.1.113 gtp bacillus subtilis 1.69 1.69 1 PMID:11078735 -2.7.1.113 utp bacillus subtilis 1.41 1.41 1 PMID:11078735 -2.7.1.119 atp streptomyces hygroscopicus 2.5 2.5 1 PMID:24200799 -2.7.1.119 hygromycin b streptomyces hygroscopicus 6.4 6.4 1 PMID:24200799 -2.7.1.12 atp homo sapiens 9.5 9.5 1 PMID:24896608 -2.7.1.12 d-gluconate homo sapiens 9.3 9.3 1 PMID:24896608 -2.7.1.121 glycerone escherichia coli 4.8 4.8 1 PMID:31126940 -2.7.1.13 2-dehydro-d-gluconate cupriavidus necator 5.8 5.8 1 PMID:31261738 -2.7.1.13 2-keto-3-deoxy-d-gluconate cupriavidus necator 10.2 10.2 1 PMID:31261738 -2.7.1.13 2-keto-3-deoxy-d-gulonate cupriavidus necator 2.1 2.1 1 PMID:31261738 -2.7.1.13 2-keto-d-gulonate cupriavidus necator 1.1 1.1 1 PMID:31261738 -2.7.1.13 atp cupriavidus necator 5.71 5.71 1 PMID:31261738 -2.7.1.130 (2-n,3-o-bis[(3r)-3-hydroxytetradecanoyl]-beta-d-glucosaminyl)-(1->6)-(2-n,3-o-bis[(3r)-3-hydroxytetradecanoyl]-alpha-d-glucosaminyl phosphate) aquifex aeolicus 2.4 2.4 1 PMID:25023290 -2.7.1.130 atp aquifex aeolicus 3.9 3.9 1 PMID:23464738 -2.7.1.136 atp escherichia coli 1.59 1.59 1 PMID:20231391 -2.7.1.14 sedoheptulose mus musculus 115.0 115.0 1 PMID:18775706 -2.7.1.145 1-(beta-d-arabinofuranosyl)-cytosine drosophila melanogaster 0.0029 0.0029 1 PMID:17302737 -2.7.1.145 1-(beta-d-arabinofuranosyl)-thymine drosophila melanogaster 0.0003 0.0003 1 PMID:17302737 -2.7.1.145 2',3'-dideoxycytidine drosophila melanogaster 4.2 4.2 1 PMID:10966789 -2.7.1.145 2'-deoxy-2',2'-difluorocytidine drosophila melanogaster 6.5 6.5 1 PMID:19285960 -2.7.1.145 2'-deoxyadenosine anopheles gambiae 0.021 0.021 1 PMID:12626708 -2.7.1.145 2'-deoxyadenosine drosophila melanogaster 20.6 20.6 4 PMID:10692477;PMID:10966789;PMID:11927571;PMID:9461577 -2.7.1.145 2'-deoxycytidine anopheles gambiae 0.03 0.03 1 PMID:12626708 -2.7.1.145 2'-deoxycytidine drosophila melanogaster 16.5 15.75 6 PMID:10692477;PMID:10966789;PMID:11927571;PMID:17302737;PMID:28323896;PMID:9461577 -2.7.1.145 2'-deoxyguanosine anopheles gambiae 0.019 0.019 1 PMID:12626708 -2.7.1.145 2'-deoxyguanosine drosophila melanogaster 19.0 15.1 5 PMID:10692477;PMID:10966789;PMID:11927571;PMID:28323896;PMID:9461577 -2.7.1.145 2'-deoxythymidine anopheles gambiae 0.014 0.014 1 PMID:12626708 -2.7.1.145 2'-deoxythymidine drosophila melanogaster 0.0142 0.0142 1 PMID:17302737 -2.7.1.145 2-amino-8-(1'-beta-d-2'-deoxyribofuranosyl)-imidazo[1,2-a]-1,3,5-triazin-4(8h)-one drosophila melanogaster 0.817 0.817 1 PMID:28323896 -2.7.1.145 3'-azido-2',3'-dideoxythymidine drosophila melanogaster 0.036 0.036 1 PMID:10966789 -2.7.1.145 5-(e)-(2-bromvinyl)-2'-deoxyuridine drosophila melanogaster 0.0059 0.0059 1 PMID:17302737 -2.7.1.145 6-amino-5-nitro-3-(1'-beta-d-2'-deoxyribofuranosyl)-2(1h)-pyridone drosophila melanogaster 0.00583 0.00583 1 PMID:28323896 -2.7.1.145 dideoxycytidine drosophila melanogaster 4.2 4.2 1 PMID:11927571 -2.7.1.145 thymidine drosophila melanogaster 15.0 14.2 4 PMID:10692477;PMID:10966789;PMID:11927571;PMID:9461577 -2.7.1.146 adp methanococcoides burtonii 0.9 0.9 1 PMID:28919057 -2.7.1.146 adp methanococcus maripaludis 48.0 39.0 2 PMID:24860874 -2.7.1.146 adp methanohalobium evestigatum 16.0 8.95 2 PMID:28919057;PMID:29997580 -2.7.1.146 adp methanosarcina mazei 6.1 6.1 1 PMID:29997580 -2.7.1.146 adp pyrococcus horikoshii 98.0 67.0 3 PMID:21906652 -2.7.1.146 adp thermococcus kodakarensis 4410.0 475.0 6 PMID:31337538 -2.7.1.146 adp uncultured bacterium 8.7 8.7 1 PMID:29997580 -2.7.1.146 amp thermococcus kodakarensis 112.0 112.0 1 PMID:31337538 -2.7.1.146 d-fructose 1,6-bisphosphate thermococcus kodakarensis 95.0 95.0 1 PMID:31337538 -2.7.1.146 d-fructose 6-phosphate methanocaldococcus jannaschii 2.7 2.7 1 PMID:28726643 -2.7.1.146 d-fructose 6-phosphate methanococcoides burtonii 8.9 8.9 1 PMID:28919057 -2.7.1.146 d-fructose 6-phosphate methanococcus maripaludis 16.5 16.5 1 PMID:24860874 -2.7.1.146 d-fructose 6-phosphate methanohalobium evestigatum 9.5 9.5 2 PMID:28919057;PMID:29997580 -2.7.1.146 d-fructose 6-phosphate methanosarcina mazei 4.6 4.6 1 PMID:29997580 -2.7.1.146 d-fructose 6-phosphate pyrococcus horikoshii 45.5 45.5 3 PMID:19553681;PMID:28726643 -2.7.1.146 d-fructose 6-phosphate thermococcus kodakarensis 4328.0 495.0 6 PMID:31337538 -2.7.1.146 d-fructose 6-phosphate uncultured bacterium 6.0 3.165 2 PMID:28726643;PMID:29997580 -2.7.1.146 d-glucose methanococcus maripaludis 23.0 23.0 1 PMID:24860874 -2.7.1.146 d-glucose thermococcus kodakarensis 104.0 104.0 2 PMID:31337538 -2.7.1.146 d-glucose 6-phosphate methanococcus maripaludis 0.678 0.678 1 PMID:24860874 -2.7.1.147 adp methanococcoides burtonii 0.8 0.8 1 PMID:28919057 -2.7.1.147 adp methanococcus maripaludis 48.0 39.0 2 PMID:24860874 -2.7.1.147 adp methanohalobium evestigatum 2.0 2.0 2 PMID:28919057;PMID:29997580 -2.7.1.147 adp methanosarcina mazei 1.7 1.7 1 PMID:29997580 -2.7.1.147 adp pyrococcus furiosus 116.0 114.0 3 PMID:21906652 -2.7.1.147 adp pyrococcus horikoshii 98.0 67.0 3 PMID:21906652 -2.7.1.147 adp thermococcus kodakarensis 210.0 210.0 2 PMID:29146530 -2.7.1.147 adp thermococcus litoralis 58.0 39.5 4 PMID:21906652;PMID:26428088 -2.7.1.147 d-fructose 6-phosphate methanococcus maripaludis 16.5 16.5 1 PMID:24860874 -2.7.1.147 d-glucosamine thermococcus kodakarensis 120.0 120.0 2 PMID:29146530 -2.7.1.147 d-glucose methanocaldococcus jannaschii 5.0 5.0 1 PMID:28726643 -2.7.1.147 d-glucose methanococcoides burtonii 14.0 14.0 1 PMID:28919057 -2.7.1.147 d-glucose methanococcus maripaludis 23.0 23.0 1 PMID:24860874 -2.7.1.147 d-glucose methanohalobium evestigatum 16.0 8.95 2 PMID:28919057;PMID:29997580 -2.7.1.147 d-glucose methanosarcina mazei 1.4 1.4 1 PMID:29997580 -2.7.1.147 d-glucose thermococcus kodakarensis 248.0 248.0 2 PMID:29146530 -2.7.1.147 d-glucose thermococcus litoralis 42.0 42.0 1 PMID:28726643 -2.7.1.147 d-glucose uncultured bacterium 3.6 1.92 2 PMID:28726643;PMID:29997580 -2.7.1.147 d-glucose 6-phosphate methanococcus maripaludis 0.678 0.678 1 PMID:24860874 -2.7.1.149 atp homo sapiens 0.0105 0.000955 3 PMID:23758345 -2.7.1.15 atp arabidopsis thaliana 2.0 2.0 1 PMID:27601466 -2.7.1.15 atp homo sapiens 9.8 8.55 2 PMID:25749547 -2.7.1.15 atp leishmania donovani 2.15 2.15 1 PMID:29400319 -2.7.1.15 atp leishmania major 10.2 10.2 1 PMID:17558452 -2.7.1.15 atp staphylococcus aureus 47.81 34.230000000000004 2 PMID:22198595 -2.7.1.15 d-ribose arabidopsis thaliana 2.0 2.0 1 PMID:27601466 -2.7.1.15 d-ribose homo sapiens 10.4 10.4 1 PMID:25749547 -2.7.1.15 d-ribose leishmania donovani 2.28 2.28 1 PMID:29400319 -2.7.1.15 d-ribose leishmania major 10.8 10.8 1 PMID:17558452 -2.7.1.156 5'-deoxyadenosylcobinamide salmonella enterica subsp. enterica serovar typhimurium 0.251 0.251 1 PMID:7559521 -2.7.1.156 atp salmonella enterica subsp. enterica serovar typhimurium 0.191 0.191 1 PMID:7559521 -2.7.1.157 atp homo sapiens 2.5 1.75 2 PMID:19531469;PMID:19874134 -2.7.1.157 n-acetyl-alpha-d-galactosamine homo sapiens 1.2 1.1 2 PMID:19874134;PMID:21984386 -2.7.1.157 n-acetyl-alpha-d-glucosamine homo sapiens 0.16 0.16 1 PMID:21984386 -2.7.1.157 n-acetyl-alpha-d-mannosamine homo sapiens 0.19 0.19 1 PMID:21984386 -2.7.1.157 n-acetyl-d-galactosamine homo sapiens 2.5 1.75 2 PMID:19531469;PMID:19874134 -2.7.1.158 1d-myo-inositol 1,3,4,5,6-pentakisphosphate arabidopsis thaliana 0.734 0.734 2 PMID:23884422;PMID:24165122 -2.7.1.158 1d-myo-inositol 1,3,4,6-tetrakisphosphate arabidopsis thaliana 0.4581 0.4581 1 PMID:23884422 -2.7.1.158 1d-myo-inositol 1,4,5,6-tetrakisphosphate arabidopsis thaliana 0.11 0.11 1 PMID:23884422 -2.7.1.158 1d-myo-inositol 3,4,5,6-tetrakisphosphate arabidopsis thaliana 0.105 0.105 2 PMID:23884422;PMID:24165122 -2.7.1.159 1d-myo-inositol-1,3,4-trisphosphate homo sapiens 20.0 12.5 2 PMID:12324474 -2.7.1.16 atp escherichia coli 0.84 0.84 1 PMID:11747300 -2.7.1.16 d-ribitol escherichia coli 109.0 109.0 1 PMID:11747300 -2.7.1.16 d-ribulose escherichia coli 74.0 74.0 1 PMID:11747300 -2.7.1.16 d-xylulose escherichia coli 33.0 33.0 1 PMID:11747300 -2.7.1.16 l-arabitol escherichia coli 64.0 64.0 1 PMID:11747300 -2.7.1.16 l-ribulose clostridium acetobutylicum 41.0 41.0 1 PMID:22194461 -2.7.1.16 l-ribulose escherichia coli 80.0 80.0 1 PMID:11747300 -2.7.1.16 l-xylulose escherichia coli 70.0 70.0 1 PMID:11747300 -2.7.1.160 18-mer 2' phosphorylated rna saccharomyces cerevisiae 0.04 0.04 1 PMID:11705403 -2.7.1.160 2'-phospho-[ligated trna] saccharomyces cerevisiae 0.0016 0.0016 1 PMID:11705403 -2.7.1.160 3-mer 2' phosphorylated rna saccharomyces cerevisiae 6.08 0.45 7 PMID:11705403 -2.7.1.160 8-mer 2' phosphorylated rna saccharomyces cerevisiae 0.317 0.317 1 PMID:11705403 -2.7.1.162 atp bifidobacterium longum 16.3 1.3 3 PMID:21799473;PMID:25644306 -2.7.1.162 atp bifidobacterium longum subsp. infantis 1.1 0.74 2 PMID:21799473 -2.7.1.162 n-acetyl-alpha-d-galactosamine bifidobacterium longum 6.08 0.752 3 PMID:17720833;PMID:21799473 -2.7.1.162 n-acetyl-alpha-d-galactosamine bifidobacterium longum subsp. infantis 0.46 0.46 1 PMID:21799473 -2.7.1.162 n-acetyl-alpha-d-glucosamine bifidobacterium longum 1.21 1.155 2 PMID:17720833;PMID:21799473 -2.7.1.162 n-acetyl-alpha-d-glucosamine bifidobacterium longum subsp. infantis 0.95 0.95 1 PMID:21799473 -2.7.1.162 n-acetyl-d-glucosamine bifidobacterium longum 9.9 9.9 1 PMID:25644306 -2.7.1.163 atp escherichia coli 5.7 5.7 1 PMID:18776672 -2.7.1.163 hygromycin b escherichia coli 5.0 5.0 1 PMID:18776672 -2.7.1.164 atp methanocaldococcus jannaschii 0.069 0.069 1 PMID:18174226 -2.7.1.164 l-seryl-trnasec methanocaldococcus jannaschii 0.098 0.098 1 PMID:18174226 -2.7.1.165 (r)-glycerate escherichia coli 2.5 2.5 1 PMID:9772162 -2.7.1.165 (r)-glycerate pyrococcus horikoshii 360.0 360.0 1 PMID:17563835 -2.7.1.165 atp escherichia coli 2.5 2.5 1 PMID:9772162 -2.7.1.165 atp pyrococcus horikoshii 500.6 500.6 1 PMID:17563835 -2.7.1.165 atp saccharolobus solfataricus 35.1 28.8 3 PMID:23279921 -2.7.1.165 atp thermoproteus tenax 3.1 3.1 1 PMID:17764545 -2.7.1.165 d-glycerate pyrococcus horikoshii 489.2 489.2 1 PMID:17563835 -2.7.1.165 d-glycerate saccharolobus solfataricus 533.3 24.5 3 PMID:23279921 -2.7.1.165 d-glycerate thermoproteus tenax 3.6 3.6 1 PMID:17764545 -2.7.1.165 d-glycerate thermotoga maritima 0.054 0.054 1 PMID:28421660 -2.7.1.169 atp thermococcus kodakarensis 1.48 1.48 2 PMID:19666462;PMID:22865846 -2.7.1.169 ctp thermococcus kodakarensis 0.47 0.47 1 PMID:22865846 -2.7.1.169 gtp thermococcus kodakarensis 0.32 0.32 1 PMID:22865846 -2.7.1.169 pantoate thermococcus kodakarensis 2.82 2.19 2 PMID:19666462;PMID:22865846 -2.7.1.169 pantothenate thermococcus kodakarensis 0.21 0.21 1 PMID:19666462 -2.7.1.169 utp thermococcus kodakarensis 1.11 1.11 1 PMID:22865846 -2.7.1.17 (polyphosphate)n thermotoga maritima 8.77 8.77 1 PMID:23584458 -2.7.1.17 atp saccharomyces cerevisiae 0.5 0.5 1 PMID:10981687 -2.7.1.17 atp thermotoga maritima 83.0 53.5 2 PMID:23584458 -2.7.1.17 d-arabitol escherichia coli 105.0 105.0 1 PMID:17123542 -2.7.1.17 d-ribulose escherichia coli 235.0 235.0 1 PMID:17123542 -2.7.1.17 d-xylulose escherichia coli 6600.0 3427.5 2 PMID:14597191;PMID:17123542 -2.7.1.17 d-xylulose homo sapiens 35.0 35.0 1 PMID:23179721 -2.7.1.17 d-xylulose saccharomyces cerevisiae 0.64 0.64 1 PMID:10981687 -2.7.1.17 d-xylulose thermotoga maritima 78.0 52.0 2 PMID:23584458 -2.7.1.17 xylitol escherichia coli 237.0 237.0 1 PMID:17123542 -2.7.1.170 1,6-anhydro-n-acetyl-beta-muramate escherichia coli 7000.0 7000.0 1 PMID:27416973 -2.7.1.173 beta-d-ribosylnicotinamide homo sapiens 0.34 0.275 2 PMID:17914902 -2.7.1.173 beta-d-ribosylnicotinate homo sapiens 1.7 0.47 6 PMID:17914902;PMID:30307159 -2.7.1.173 cytidine homo sapiens 0.82 0.6499999999999999 2 PMID:17914902 -2.7.1.173 tiazofurin homo sapiens 0.49 0.42 2 PMID:17914902 -2.7.1.173 uridine homo sapiens 1.1 0.655 2 PMID:17914902 -2.7.1.176 atp neisseria gonorrhoeae 280.0 1.76 3 PMID:29703974 -2.7.1.176 udp-alpha-d-glucose neisseria gonorrhoeae 0.71 0.71 1 PMID:29703974 -2.7.1.176 udp-muramic acid neisseria gonorrhoeae 200.0 200.0 1 PMID:29703974 -2.7.1.176 udp-n-acetyl-alpha-d-glucosamine neisseria gonorrhoeae 1.72 1.72 1 PMID:29703974 -2.7.1.177 atp salmonella enterica 0.408 0.408 1 PMID:19509296 -2.7.1.177 l-threonine salmonella enterica 0.0427 0.0427 1 PMID:19509296 -2.7.1.178 2-dehydro-3-deoxy-d-galactonate saccharolobus solfataricus 5.4 5.4 1 PMID:16330030 -2.7.1.178 2-dehydro-3-deoxy-d-gluconate saccharolobus solfataricus 60.8 32.9 2 PMID:16330030;PMID:16794308 -2.7.1.178 atp saccharolobus solfataricus 3.8 3.8 1 PMID:16330030 -2.7.1.180 [protein nqrc]-l-threonine vibrio cholerae 0.16 0.16 1 PMID:31350338 -2.7.1.180 fad vibrio cholerae 0.16 0.16 1 PMID:31350338 -2.7.1.185 (r)-mevalonate picrophilus oshimae 1.9 1.9 1 PMID:25636853 -2.7.1.185 (r)-mevalonate thermoplasma acidophilum 5.3 5.15 2 PMID:24914732;PMID:25422158 -2.7.1.186 (r)-3-phosphomevalonate thermoplasma acidophilum 9.0 9.0 1 PMID:24914732 -2.7.1.189 (s)-4,5-dihydroxypentane-2,3-dione escherichia coli 17.0 17.0 1 PMID:29868643 -2.7.1.189 1,2-dihydroxyheptane-3,4-dione salmonella enterica 5.8 5.8 1 PMID:23672516 -2.7.1.189 1,2-dihydroxyhexane-3,4-dione salmonella enterica 5.8 5.8 1 PMID:23672516 -2.7.1.189 1,2-dihydroxyoctane-3,4-dione salmonella enterica 1.5 1.5 1 PMID:23672516 -2.7.1.189 4,5-dihydroxypentane-2,3-dione salmonella enterica 7.6 7.6 1 PMID:23672516 -2.7.1.189 atp salmonella enterica 7.6 7.6 1 PMID:23672516 -2.7.1.190 amikacin campylobacter jejuni 6.5 6.5 1 PMID:23129050 -2.7.1.190 amikacin staphylococcus aureus 3.7 3.7 1 PMID:23115238 -2.7.1.190 arbekacin campylobacter jejuni 4.3 4.3 1 PMID:23129050 -2.7.1.190 arbekacin staphylococcus aureus 2.3 2.3 1 PMID:23115238 -2.7.1.190 atp campylobacter jejuni 0.38 0.38 1 PMID:23129050 -2.7.1.190 atp enterococcus casseliflavus 4.37 4.37 1 PMID:22371504 -2.7.1.190 atp enterococcus sp. 0.09 0.09 1 PMID:18199745 -2.7.1.190 dibekacin campylobacter jejuni 0.79 0.79 1 PMID:23129050 -2.7.1.190 dibekacin enterococcus sp. 0.7 0.7 1 PMID:18199745 -2.7.1.190 dibekacin staphylococcus aureus 0.15 0.15 1 PMID:23115238 -2.7.1.190 gentamicin c campylobacter jejuni 8.3 8.3 1 PMID:23129050 -2.7.1.190 gentamicin c enterococcus sp. 0.5 0.5 1 PMID:18199745 -2.7.1.190 gentamicin c staphylococcus aureus 3.0 3.0 1 PMID:23115238 -2.7.1.190 gtp campylobacter jejuni 0.4 0.4 1 PMID:23129050 -2.7.1.190 gtp enterococcus casseliflavus 5.03 5.03 1 PMID:22371504 -2.7.1.190 gtp enterococcus sp. 0.8 0.8 1 PMID:18199745 -2.7.1.190 isepamicin campylobacter jejuni 0.25 0.25 1 PMID:23129050 -2.7.1.190 itp enterococcus sp. 2.1 2.1 1 PMID:18199745 -2.7.1.190 kanamycin a campylobacter jejuni 1.7 1.7 1 PMID:23129050 -2.7.1.190 kanamycin a enterococcus sp. 0.8 0.8 1 PMID:18199745 -2.7.1.190 kanamycin a staphylococcus aureus 0.57 0.57 1 PMID:23115238 -2.7.1.190 kanamycin b campylobacter jejuni 0.38 0.38 1 PMID:23129050 -2.7.1.190 kanamycin b staphylococcus aureus 0.12 0.12 1 PMID:23115238 -2.7.1.190 netilmicin campylobacter jejuni 18.0 18.0 1 PMID:23129050 -2.7.1.190 netilmicin enterococcus sp. 0.7 0.7 1 PMID:18199745 -2.7.1.190 netilmicin staphylococcus aureus 6.5 6.5 1 PMID:23115238 -2.7.1.190 sisomicin campylobacter jejuni 17.0 17.0 1 PMID:23129050 -2.7.1.190 sisomicin staphylococcus aureus 8.1 8.1 1 PMID:23115238 -2.7.1.190 tobramycin campylobacter jejuni 0.48 0.48 1 PMID:23129050 -2.7.1.190 tobramycin enterococcus sp. 0.7 0.7 1 PMID:18199745 -2.7.1.190 tobramycin staphylococcus aureus 0.11 0.11 1 PMID:23115238 -2.7.1.190 utp enterococcus sp. 0.14 0.14 1 PMID:18199745 -2.7.1.191 gdp-d-mannose clostridioides difficile 2.248 2.248 1 PMID:32073825 -2.7.1.191 glcbeta1,3-galnac-pp-cph clostridioides difficile 2.738 2.738 1 PMID:32073825 -2.7.1.2 atp kluyveromyces lactis 400.0 400.0 1 PMID:31569356 -2.7.1.2 atp leishmania major 317.0 317.0 1 PMID:17904661 -2.7.1.2 atp methylomonas methanica 0.126 0.126 1 PMID:30769875 -2.7.1.2 atp methylotuvimicrobium alcaliphilum 252.8 252.8 1 PMID:27915410 -2.7.1.2 atp naegleria fowleri 36.5 36.5 1 PMID:30783001 -2.7.1.2 atp trypanosoma cruzi 1492.0 1492.0 1 PMID:17904661 -2.7.1.2 d-glucosamine methylotuvimicrobium alcaliphilum 293.5 293.5 1 PMID:27915410 -2.7.1.2 d-glucose escherichia coli k-12 410.0 10.6 4 PMID:15157072 -2.7.1.2 d-glucose kluyveromyces lactis 150.0 150.0 1 PMID:31569356 -2.7.1.2 d-glucose leishmania major 317.0 317.0 1 PMID:17904661 -2.7.1.2 d-glucose methylomonas methanica 0.1095 0.1095 1 PMID:30769875 -2.7.1.2 d-glucose methylotuvimicrobium alcaliphilum 257.7 257.7 1 PMID:27915410 -2.7.1.2 d-glucose naegleria fowleri 36.5 36.5 1 PMID:30783001 -2.7.1.2 d-glucose pyrobaculum calidifontis 289.0 289.0 1 PMID:29275440 -2.7.1.2 d-glucose shewanella woodyi 0.67 0.21 3 PMID:29169041 -2.7.1.2 d-glucose thermotoga maritima 92.6 92.6 1 PMID:12814622 -2.7.1.2 d-glucose trypanosoma cruzi 1492.0 749.9 2 PMID:17904661;PMID:26778112 -2.7.1.20 2'-deoxyadenosine leishmania donovani 5.25 5.25 1 PMID:16271040 -2.7.1.20 2'-deoxyadenosine saccharomyces cerevisiae 1.0 1.0 1 PMID:12883639 -2.7.1.20 3'-deoxyadenosine leishmania donovani 6.7 6.7 1 PMID:16271040 -2.7.1.20 adenosine anopheles gambiae 0.63 0.056 5 PMID:21247194 -2.7.1.20 adenosine cricetulus griseus 13.0 0.495 6 PMID:15106882;PMID:15917509 -2.7.1.20 adenosine homo sapiens 0.5 0.5 2 PMID:21319802;PMID:26242695 -2.7.1.20 adenosine leishmania donovani 24.15 21.0 4 PMID:15606359;PMID:16271040;PMID:2538441 -2.7.1.20 adenosine saccharomyces cerevisiae 25.5 25.5 1 PMID:12883639 -2.7.1.20 adenosine trypanosoma brucei 8.1 8.1 1 PMID:18167353 -2.7.1.20 atp anopheles gambiae 0.33 0.33 1 PMID:21247194 -2.7.1.20 atp cryptosporidium parvum 2.6 2.6 1 PMID:16879885 -2.7.1.20 atp leishmania donovani 24.15 18.0 3 PMID:15606359;PMID:16271040 -2.7.1.20 atp trypanosoma brucei 7.3 7.3 1 PMID:18167353 -2.7.1.20 cordycepin trypanosoma brucei 3.9 3.9 1 PMID:18167353 -2.7.1.20 ctp anopheles gambiae 0.062 0.062 1 PMID:21247194 -2.7.1.20 ctp trypanosoma brucei 20.0 20.0 1 PMID:18167353 -2.7.1.20 cytidine saccharomyces cerevisiae 1.02 1.02 1 PMID:12883639 -2.7.1.20 deoxyadenosine trypanosoma brucei 4.2 4.2 1 PMID:18167353 -2.7.1.20 fludarabine trypanosoma brucei 0.11 0.11 1 PMID:18167353 -2.7.1.20 gtp anopheles gambiae 1.39 1.39 1 PMID:21247194 -2.7.1.20 gtp trypanosoma brucei 16.0 16.0 1 PMID:18167353 -2.7.1.20 guanosine saccharomyces cerevisiae 0.5 0.5 1 PMID:12883639 -2.7.1.20 inosine saccharomyces cerevisiae 0.583 0.583 1 PMID:12883639 -2.7.1.20 inosine trypanosoma brucei 1.1 1.1 1 PMID:18167353 -2.7.1.20 ribavirin cricetulus griseus 1.8 1.21 2 PMID:15917509 -2.7.1.20 ttp anopheles gambiae 0.3 0.3 1 PMID:21247194 -2.7.1.20 uridine saccharomyces cerevisiae 1.67 1.67 1 PMID:12883639 -2.7.1.20 utp anopheles gambiae 0.061 0.061 1 PMID:21247194 -2.7.1.20 utp trypanosoma brucei 18.0 18.0 1 PMID:18167353 -2.7.1.20 viramidine cricetulus griseus 0.26 0.21000000000000002 2 PMID:15917509 -2.7.1.209 d-erythrulose mycolicibacterium smegmatis 1.6 1.6 1 PMID:26560079 -2.7.1.209 dihydroxyacetone mycolicibacterium smegmatis 2.12 2.12 1 PMID:26560079 -2.7.1.209 l-erythrulose mycolicibacterium smegmatis 1.79 1.79 1 PMID:26560079 -2.7.1.21 (e)-5-(2-bromovinyl)-2'-deoxyuridine herpes simplex virus 0.0253 0.0253 1 PMID:17023224 -2.7.1.21 2',3'-didehydro-2',3'-dideoxythymidine cryptosporidium parvum 0.03 0.03 1 PMID:20231284 -2.7.1.21 2',3'-dideoxy-2',3'-didehydrothymidine thermotoga maritima 0.41 0.41 1 PMID:17592850 -2.7.1.21 2',3'-dideoxy-3'-azidothymidine thermotoga maritima 1.6 0.9450000000000001 2 PMID:17592850 -2.7.1.21 2',3'-dideoxythymidine thermotoga maritima 0.33 0.33 1 PMID:17592850 -2.7.1.21 2'-deoxythymidine canid alphaherpesvirus 1 6.47 6.47 1 PMID:17065088 -2.7.1.21 2'-deoxythymidine felid alphaherpesvirus 1 23.0 23.0 1 PMID:17065088 -2.7.1.21 2'-deoxythymidine leishmania major 262.0 262.0 1 PMID:25978379 -2.7.1.21 2'-deoxythymidine orthopoxvirus vaccinia 220.0 110.1 2 PMID:17065088;PMID:17335913 -2.7.1.21 2'-deoxyuridine leishmania major 3.06 3.06 1 PMID:25978379 -2.7.1.21 2'-deoxyuridine thermotoga maritima 0.7 0.7 1 PMID:17592850 -2.7.1.21 2'-fluoro-5-methyl-beta-l-arabinofuranosyluracil thermotoga maritima 0.5 0.5 1 PMID:17592850 -2.7.1.21 3'-azido-2',3'-dideoxythymidine cryptosporidium parvum 0.17 0.17 1 PMID:20231284 -2.7.1.21 3'-azido-3'-deoxythymidine arabidopsis thaliana 0.13 0.0695 2 PMID:22897443 -2.7.1.21 3'-azido-3'-deoxythymidine caenorhabditis elegans 9.3 9.3 1 PMID:22385435 -2.7.1.21 3'-azido-3'-deoxythymidine canid alphaherpesvirus 1 0.53 0.53 1 PMID:17065088 -2.7.1.21 3'-azido-3'-deoxythymidine felid alphaherpesvirus 1 0.97 0.97 1 PMID:17065088 -2.7.1.21 3'-azido-3'-deoxythymidine homo sapiens 3.5 3.5 1 PMID:22385435 -2.7.1.21 3'-azido-3'-deoxythymidine leishmania major 1.97 1.97 1 PMID:25978379 -2.7.1.21 3'-azido-3'-deoxythymidine orthopoxvirus vaccinia 412.0 412.0 1 PMID:17065088 -2.7.1.21 3-[1(2)-closo-1,7-carboranylbutyltetrazol-5-yl]thymidine homo sapiens 0.32 0.32 1 PMID:23318906 -2.7.1.21 3-[1(2)-closo-1,7-carboranylbutyltetrazol-5-ylmethyl]thymidine homo sapiens 0.47 0.47 1 PMID:23318906 -2.7.1.21 3-[1(2)-closo-1,7-carboranylethyltetrazol-5-yl]thymidine homo sapiens 0.35 0.35 1 PMID:23318906 -2.7.1.21 3-[1(2)-closo-1,7-carboranylethyltetrazol-5-ylmethyl]thymidine homo sapiens 0.44 0.44 1 PMID:23318906 -2.7.1.21 3-[1(2)-closo-1,7-carboranylpropyltetrazol-5-yl]thymidine homo sapiens 0.37 0.37 1 PMID:23318906 -2.7.1.21 3-[1(2)-closo-1,7-carboranylpropyltetrazol-5-ylmethyl]thymidine homo sapiens 0.39 0.39 1 PMID:23318906 -2.7.1.21 3-[1(2)-propyltetrazol-5-yl]thymidine homo sapiens 0.34 0.34 1 PMID:23318906 -2.7.1.21 3-[1(2)-propyltetrazol-5-ylmethyl]thymidine homo sapiens 0.45 0.45 1 PMID:23318906 -2.7.1.21 5-bromo-2'-deoxyuridine leishmania major 3.47 3.47 1 PMID:25978379 -2.7.1.21 5-fluoro-2'-deoxyuridine cryptosporidium parvum 0.24 0.24 1 PMID:20231284 -2.7.1.21 5-fluoro-2'-deoxyuridine leishmania major 4.66 4.66 1 PMID:25978379 -2.7.1.21 5-fluoro-2'-deoxyuridine thermotoga maritima 0.74 0.74 1 PMID:17592850 -2.7.1.21 5-fluorodeoxyuridine trypanosoma brucei 3.6 3.6 1 PMID:22442154 -2.7.1.21 5-hydroxymethyl-2'-deoxyuridine leishmania major 2.82 2.82 1 PMID:25978379 -2.7.1.21 aciclovir monophosphate herpes simplex virus 0.238 0.238 1 PMID:17023224 -2.7.1.21 acyclovir herpes simplex virus 0.015 0.015 1 PMID:12192082 -2.7.1.21 atp cryptosporidium parvum 0.28 0.28 1 PMID:20231284 -2.7.1.21 atp human gammaherpesvirus 4 8.0 8.0 1 PMID:15779905 -2.7.1.21 atp thermotoga maritima 3.5 1.95 2 PMID:17592850 -2.7.1.21 atp trypanosoma brucei 3.9 3.5 2 PMID:22442154 -2.7.1.21 beta-l-thymidine cryptosporidium parvum 0.007 0.007 1 PMID:20231284 -2.7.1.21 ctp human gammaherpesvirus 4 19.0 19.0 1 PMID:15779905 -2.7.1.21 deoxyadenosine trypanosoma brucei 0.047 0.047 1 PMID:22442154 -2.7.1.21 deoxycytidine herpes simplex virus 1.4 1.4 1 PMID:9866691 -2.7.1.21 deoxyguanosine trypanosoma brucei 0.34 0.34 1 PMID:22442154 -2.7.1.21 deoxyinosine trypanosoma brucei 0.8 0.8 1 PMID:22442154 -2.7.1.21 deoxyuridine arabidopsis thaliana 1.5 0.7725 2 PMID:22897443 -2.7.1.21 deoxyuridine cryptosporidium parvum 0.53 0.53 1 PMID:20231284 -2.7.1.21 deoxyuridine herpes simplex virus 1.3 1.3 1 PMID:9866691 -2.7.1.21 deoxyuridine trypanosoma brucei 5.3 5.199999999999999 2 PMID:22442154 -2.7.1.21 dioxolane thymidine thermotoga maritima 0.29 0.29 1 PMID:17592850 -2.7.1.21 ganciclovir herpes simplex virus 0.47 0.285 2 PMID:10747801;PMID:12192082 -2.7.1.21 ganciclovir monophosphate herpes simplex virus 0.0272 0.0272 1 PMID:17023224 -2.7.1.21 gtp human gammaherpesvirus 4 21.0 21.0 1 PMID:15779905 -2.7.1.21 thymidine arabidopsis thaliana 0.48 0.25 2 PMID:22897443 -2.7.1.21 thymidine caenorhabditis elegans 6.4 6.4 1 PMID:22385435 -2.7.1.21 thymidine cryptosporidium parvum 0.28 0.28 1 PMID:20231284 -2.7.1.21 thymidine herpes simplex virus 0.46 0.26 2 PMID:10747801;PMID:12192082 -2.7.1.21 thymidine homo sapiens 282.0 9.5 3 PMID:14697231;PMID:22385435;PMID:23318906 -2.7.1.21 thymidine thermotoga maritima 3.5 1.9 2 PMID:17592850 -2.7.1.21 thymidine trypanosoma brucei 3.5 3.3 2 PMID:22442154 -2.7.1.21 trifluoromethylthymidine cryptosporidium parvum 0.36 0.36 1 PMID:20231284 -2.7.1.21 ttp human gammaherpesvirus 4 11.0 11.0 1 PMID:15779905 -2.7.1.21 uridine leishmania major 0.44 0.44 1 PMID:25978379 -2.7.1.21 uridine trypanosoma brucei 1.5 1.5 1 PMID:22442154 -2.7.1.210 d-erythrulose mycolicibacterium smegmatis 2.88 1.4855 2 PMID:26560079 -2.7.1.210 dihydroxyacetone mycolicibacterium smegmatis 0.063 0.063 1 PMID:26560079 -2.7.1.212 2-deoxy-alpha-d-ribose 1-phosphate thermococcus kodakarensis 73.0 73.0 1 PMID:25822915 -2.7.1.212 2-deoxy-alpha-d-ribose-1-phosphate thermococcus kodakarensis 73.0 73.0 1 PMID:25822915 -2.7.1.212 adp thermococcus kodakarensis 1160.0 734.0 4 PMID:25822915 -2.7.1.212 alpha-d-ribose 1-phosphate thermococcus kodakarensis 485.0 485.0 1 PMID:25822915 -2.7.1.212 alpha-d-ribose-1-phosphate thermococcus kodakarensis 485.0 485.0 1 PMID:25822915 -2.7.1.212 gdp thermococcus kodakarensis 189.0 189.0 2 PMID:25822915 -2.7.1.213 3'-deoxycytidine thermococcus kodakarensis 226.0 226.0 1 PMID:25822915 -2.7.1.213 atp thermococcus kodakarensis 222.0 222.0 1 PMID:25822915 -2.7.1.213 cytidine thermococcus kodakarensis 280.0 280.0 1 PMID:25822915 -2.7.1.214 validone streptomyces hygroscopicus subsp. jinggangensis 7.3 7.3 1 PMID:17335096 -2.7.1.214 valienone streptomyces hygroscopicus subsp. jinggangensis 3.5 3.5 1 PMID:17335096 -2.7.1.215 atp brucella abortus 230.0 230.0 1 PMID:12639570 -2.7.1.215 meso-erythritol brucella abortus 230.0 230.0 1 PMID:12639570 -2.7.1.219 4-hydroxy-l-threonine cupriavidus necator 27.0 27.0 1 PMID:27402745 -2.7.1.219 4-hydroxy-l-threonine salmonella enterica subsp. enterica serovar typhimurium 4.0 4.0 1 PMID:27402745 -2.7.1.219 d-threonate cupriavidus necator 45.0 45.0 1 PMID:27402745 -2.7.1.219 d-threonate salmonella enterica subsp. enterica serovar typhimurium 22.0 22.0 1 PMID:27402745 -2.7.1.22 1-(beta-d-ribofuranosyl)-nicotinamide homo sapiens 1.7 0.675 4 PMID:30307159 -2.7.1.22 nicotinamide mononucleotide haemophilus influenzae 0.92 0.92 1 PMID:12446641 -2.7.1.220 4-hydroxy-l-threonine heliomicrobium modesticaldum 41.0 41.0 1 PMID:27402745 -2.7.1.220 d-erythronate heliomicrobium modesticaldum 16.0 16.0 1 PMID:27402745 -2.7.1.220 d-threonate heliomicrobium modesticaldum 12.0 12.0 1 PMID:27402745 -2.7.1.221 2-(2-azidoacetamido)-3-o-[(1r)-1-carboxyethyl]-2-deoxy-d-glucopyranose pseudomonas putida 14.07 14.07 2 PMID:29986130;PMID:32416908 -2.7.1.221 2-[(but-3-ynoyl)amino]-3-o-[(1r)-1-carboxyethyl]-2-deoxy-d-glucopyranose pseudomonas putida 9.74 9.74 2 PMID:29986130;PMID:32416908 -2.7.1.221 2-acetamido-3-o-[(1r)-1-carboxyethyl]-2-deoxy-d-glucopyranose pseudomonas putida 6.58 6.58 1 PMID:32416908 -2.7.1.221 2-acetamido-3-o-[(1r)-2-azido-1-carboxyethyl]-2-deoxy-d-glucopyranose pseudomonas putida 4.67 4.67 2 PMID:29986130;PMID:32416908 -2.7.1.221 atp pseudomonas putida 4.38 4.38 1 PMID:23831760 -2.7.1.221 n-acetyl-d-glucosamine pseudomonas putida 6.64 6.64 1 PMID:23831760 -2.7.1.221 n-acetyl-d-muramate pseudomonas putida 5.15 5.15 1 PMID:23831760 -2.7.1.222 4-hydroxytryptamine psilocybe cubensis 4.5 4.5 1 PMID:32101345 -2.7.1.222 psilocin psilocybe cubensis 16.1 16.1 1 PMID:32101345 -2.7.1.224 2'-deoxycytidine 5'-diphosphoramidate campylobacter jejuni subsp. jejuni serotype o:2 2.2 2.2 1 PMID:29578334 -2.7.1.224 atp campylobacter jejuni subsp. jejuni serotype o:2 2.2 2.2 1 PMID:29578334 -2.7.1.224 cdp-methyl phosphonate campylobacter jejuni subsp. jejuni serotype o:2 1.4 1.4 1 PMID:29578334 -2.7.1.224 cytidine 5'-diphosphoramidate campylobacter jejuni subsp. jejuni serotype o:2 2.2 2.2 1 PMID:29578334 -2.7.1.226 adp thermococcus kodakarensis 204.0 204.0 1 PMID:27857065 -2.7.1.226 l-serine thermococcus kodakarensis 218.0 218.0 1 PMID:27857065 -2.7.1.23 adp corynebacterium glutamicum 2.3 2.3 1 PMID:20180116 -2.7.1.23 atp bacillus subtilis 1.36 1.36 1 PMID:12897004 -2.7.1.23 atp corynebacterium glutamicum 29.2 14.86 2 PMID:20180116;PMID:22664190 -2.7.1.23 atp corynebacterium glutamicum subsp. lactofermentum 2.54 2.54 1 PMID:22664190 -2.7.1.23 atp entamoeba histolytica 2.68 2.35 2 PMID:23069387 -2.7.1.23 atp escherichia coli 55.0 55.0 1 PMID:11488932 -2.7.1.23 atp listeria monocytogenes 13.78 13.78 1 PMID:17686780 -2.7.1.23 atp methanocaldococcus jannaschii 399.0 399.0 1 PMID:16192277 -2.7.1.23 atp sphingomonas sp. 30.33 30.33 1 PMID:15177293 -2.7.1.23 fructose-1,6-bisphosphate methanocaldococcus jannaschii 212.0 212.0 1 PMID:18391451 -2.7.1.23 nad+ bacillus subtilis 5.46 5.46 1 PMID:12897004 -2.7.1.23 nad+ corynebacterium glutamicum 27.1 7.8 3 PMID:20180116;PMID:22664190 -2.7.1.23 nad+ corynebacterium glutamicum subsp. lactofermentum 3.8 3.8 1 PMID:22664190 -2.7.1.23 nad+ entamoeba histolytica 1.9 1.9 1 PMID:23069387 -2.7.1.23 nad+ escherichia coli 125.0 125.0 1 PMID:11488932 -2.7.1.23 nad+ listeria monocytogenes 13.12 8.37 2 PMID:17686780 -2.7.1.23 nad+ methanocaldococcus jannaschii 424.0 424.0 1 PMID:16192277 -2.7.1.23 nad+ sphingomonas sp. 2.95 2.95 1 PMID:15177293 -2.7.1.23 nadh entamoeba histolytica 1.9 1.9 1 PMID:23069387 -2.7.1.23 nadp+ methanocaldococcus jannaschii 212.0 212.0 1 PMID:18391451 -2.7.1.23 nadph methanocaldococcus jannaschii 236.0 236.0 1 PMID:18391451 -2.7.1.23 polyphosphate(20) corynebacterium glutamicum 7.8 7.8 1 PMID:20180116 -2.7.1.23 polyphosphate(25) corynebacterium glutamicum 7.3 7.3 1 PMID:20180116 -2.7.1.23 polyphosphate(45) corynebacterium glutamicum 3.4 3.4 1 PMID:20180116 -2.7.1.23 polyphosphate(65) corynebacterium glutamicum 3.4 3.4 1 PMID:20180116 -2.7.1.23 polyphosphate(75) corynebacterium glutamicum 1.8 1.8 1 PMID:20180116 -2.7.1.23 tetraphosphate corynebacterium glutamicum 8.7 8.7 1 PMID:20180116 -2.7.1.23 triphosphate corynebacterium glutamicum 3.0 3.0 1 PMID:20180116 -2.7.1.235 atp pseudomonas aeruginosa 0.45 0.45 1 PMID:12019135 -2.7.1.236 atp xanthomonas oryzae pv. oryzicola 460.0 400.0 2 PMID:27621317 -2.7.1.236 naad+ xanthomonas oryzae pv. oryzicola 270.0 270.0 1 PMID:27621317 -2.7.1.236 nad+ xanthomonas oryzae pv. oryzicola 430.0 430.0 1 PMID:27621317 -2.7.1.237 3'-dephospho-coa thermococcus kodakarensis 5.57 5.57 1 PMID:31337720 -2.7.1.237 gtp thermococcus kodakarensis 6.68 6.68 1 PMID:31337720 -2.7.1.24 3'-dephospho-coa entamoeba histolytica 1.48 1.22 2 PMID:30555442 -2.7.1.24 3'-dephospho-coa mycobacterium tuberculosis 0.0293 0.0293 1 PMID:21264299 -2.7.1.24 3'-dephospho-coa thermococcus kodakarensis 5.57 5.57 1 PMID:31337720 -2.7.1.24 atp entamoeba histolytica 1.41 1.23 2 PMID:30555442 -2.7.1.24 atp mycobacterium tuberculosis 0.0481 0.0481 1 PMID:21264299 -2.7.1.24 gtp thermococcus kodakarensis 6.68 6.68 1 PMID:31337720 -2.7.1.25 adenosine 5'-o-(3-thiotriphosphate) escherichia coli 0.09 0.09 1 PMID:10860538 -2.7.1.25 adenosine 5'-phosphosulfate arabidopsis thaliana 272.0 177.15 6 PMID:22184237;PMID:22810229;PMID:23322773 -2.7.1.25 adenosine 5-phosphosulfate escherichia coli 50.0 50.0 1 PMID:2549047 -2.7.1.25 adenosine-5'-phosphosulfate oryza sativa 5.0 5.0 1 * -2.7.1.25 adenylyl sulfate homo sapiens 0.364 0.364 1 PMID:17540769 -2.7.1.25 atp homo sapiens 4.4 2.3 3 PMID:11931637 -2.7.1.26 atp corynebacterium ammoniagenes 6.8 2.385 6 PMID:22892871;PMID:23203077;PMID:25801930;PMID:28779158 -2.7.1.26 atp homo sapiens 1.7 1.7 1 PMID:32649804 -2.7.1.26 atp neurospora crassa 0.1 0.1 1 PMID:10650711 -2.7.1.26 riboflavin bacillus subtilis 0.7 0.7 1 PMID:18156273 -2.7.1.26 riboflavin corynebacterium ammoniagenes 7.33 6.0649999999999995 6 PMID:22892871;PMID:23203077;PMID:25801930;PMID:28779158 -2.7.1.26 riboflavin homo sapiens 1.7 1.7 1 PMID:32649804 -2.7.1.26 riboflavin neurospora crassa 0.1 0.1 1 PMID:10650711 -2.7.1.26 riboflavin streptomyces davaonensis 0.3 0.3 1 PMID:18156273 -2.7.1.26 roseoflavin bacillus subtilis 0.4 0.4 1 PMID:18156273 -2.7.1.26 roseoflavin streptomyces davaonensis 0.5 0.5 1 PMID:18156273 -2.7.1.27 atp brucella abortus 230.0 230.0 1 PMID:12639570 -2.7.1.27 meso-erythritol brucella abortus 230.0 230.0 1 PMID:12639570 -2.7.1.28 atp homo sapiens 4.59 4.265 2 PMID:24569995 -2.7.1.28 d-glyceraldehyde homo sapiens 4.83 4.83 1 PMID:24569995 -2.7.1.28 dihydroxyacetone homo sapiens 5.0 5.0 1 PMID:24569995 -2.7.1.29 atp citrobacter freundii 24.02 24.02 1 PMID:26610480 -2.7.1.29 d,l-glyceraldehyde citrobacter freundii 5.17 5.17 1 PMID:15476397 -2.7.1.29 dihydroxyacetone citrobacter freundii 24.13 24.13 1 PMID:20198665 -2.7.1.29 dihydroxyacetone escherichia coli 8.45 2.8 4 PMID:11350937;PMID:21209328 -2.7.1.29 glycerone phosphate citrobacter freundii 17.5 17.5 1 PMID:15476397 -2.7.1.29 glycerone phosphate escherichia coli 4.8 4.8 1 PMID:15476397 -2.7.1.3 d-fructose homo sapiens 7.6 6.4 4 PMID:12941785 -2.7.1.3 d-ribose homo sapiens 8.2 4.875 2 PMID:12941785 -2.7.1.3 d-ribulose homo sapiens 7.6 6.199999999999999 2 PMID:12941785 -2.7.1.3 d-xylulose homo sapiens 11.1 9.35 2 PMID:12941785 -2.7.1.3 l-sorbose homo sapiens 6.5 5.85 2 PMID:12941785 -2.7.1.30 atp thermococcus kodakarensis 4.02 4.02 1 PMID:32008925 -2.7.1.30 glycerol candida mycoderma 1670.0 1670.0 1 * -2.7.1.30 glycerol cellulomonas sp. 4900.0 4900.0 1 PMID:26493633 -2.7.1.31 d-glycerate escherichia coli 350.0 350.0 1 * -2.7.1.31 d-glycerate spinacia oleracea 200.0 200.0 1 PMID:2981505 -2.7.1.32 atp homo sapiens 54.39 29.445 2 PMID:27149373;PMID:29389115 -2.7.1.32 choline caenorhabditis elegans 74.0 73.15 2 PMID:14960577 -2.7.1.32 choline homo sapiens 76.83 71.0 7 PMID:17007874;PMID:20299452;PMID:23416529;PMID:27149373;PMID:29389115 -2.7.1.32 choline saccharomyces cerevisiae 2.55 2.55 1 PMID:9506987 -2.7.1.32 choline streptococcus pneumoniae 5.1 4.12 2 PMID:25781969;PMID:32963303 -2.7.1.32 choline trypanosoma brucei 12.91 12.91 1 PMID:18489261 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-(3-[[2-oxo-2-(pentylamino)ethyl]amino]propyl)butanamide escherichia coli 0.13 0.13 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-(3-[[3-(morpholin-4-yl)propyl]amino]-3-oxopropyl)butanamide escherichia coli 1.03 1.03 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-(3-oxo-3-[[(piperidin-4-yl)methyl]amino]propyl)butanamide escherichia coli 1.19 1.19 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-(3-oxo-3-[[2-(piperazin-1-yl)ethyl]amino]propyl)butanamide escherichia coli 0.75 0.75 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-(3-oxo-3-[[2-(pyridin-2-yl)ethyl]amino]propyl)butanamide escherichia coli 1.15 1.15 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-[(1-pentyl-1h-1,2,3-triazol-4-yl)methyl]butanamide escherichia coli 0.96 0.96 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-[3-(1-propyl-1h-1,2,3-triazol-4-yl)propyl]butanamide escherichia coli 0.49 0.49 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-[3-[(3-methylpyridin-2-yl)amino]-3-oxopropyl]butanamide escherichia coli 0.78 0.78 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-[3-oxo-3-(pentylamino)propyl]butanamide escherichia coli 0.93 0.93 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-[3-oxo-3-(phenylamino)propyl]butanamide escherichia coli 1.02 1.02 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-[3-oxo-3-(pyrimidin-4-ylamino)propyl]butanamide escherichia coli 1.44 1.44 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-[3-oxo-3-[(3-phenylpropyl)amino]propyl]butanamide escherichia coli 1.13 1.13 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-[3-oxo-3-[(pyridin-2-ylmethyl)amino]propyl]butanamide escherichia coli 1.02 1.02 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-[3-oxo-3-[(pyridin-3-ylmethyl)amino]propyl]butanamide escherichia coli 1.24 1.24 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-3,3-dimethyl-n-[3-oxo-3-[(pyridin-4-ylmethyl)amino]propyl]butanamide escherichia coli 0.94 0.94 1 PMID:24814884 -2.7.1.33 (2r)-2,4-dihydroxy-n-(3-[[3-(1h-imidazol-1-yl)propyl]amino]-3-oxopropyl)-3,3-dimethylbutanamide escherichia coli 0.46 0.46 1 PMID:24814884 -2.7.1.33 (2r)-n-[3-(1,3-dihydro-2h-isoindol-2-yl)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide escherichia coli 0.45 0.45 1 PMID:24814884 -2.7.1.33 (2r)-n-[3-(2,3-dihydro-1h-indol-1-yl)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide escherichia coli 0.18 0.18 1 PMID:24814884 -2.7.1.33 (2r)-n-[3-(benzylamino)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide escherichia coli 1.15 1.15 1 PMID:24814884 -2.7.1.33 (2r)-n-[3-[(2-butanamidoethyl)amino]-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide escherichia coli 1.09 1.09 1 PMID:24814884 -2.7.1.33 (2s)-2-hydroxy-3-(hydroxymethyl)-3-methyl-n-[3-oxo-3-(pentylamino)propyl]pentanamide escherichia coli 1.17 1.17 1 PMID:24814884 -2.7.1.33 (2s)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-n-[3-oxo-3-(pentylamino)propyl]hept-6-ynamide escherichia coli 1.04 1.04 1 PMID:24814884 -2.7.1.33 (2s)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-n-[3-oxo-3-(pentylamino)propyl]hex-5-enamide escherichia coli 0.89 0.585 2 PMID:24814884 -2.7.1.33 (r)-pantothenate bacillus subtilis 2.12 2.12 1 PMID:15795230 -2.7.1.33 (r)-pantothenate escherichia coli 1.07 1.07 1 PMID:24814884 -2.7.1.33 (r)-pantothenate helicobacter pylori 2.09 2.09 1 PMID:15795230 -2.7.1.33 (r)-pantothenate staphylococcus aureus 1.7 1.7 1 PMID:15548531 -2.7.1.33 (r)-pantothenate thermotoga maritima 0.29 0.29 1 PMID:16855243 -2.7.1.33 3-[[(2r)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]-2-(pentylamino)propanoate escherichia coli 0.23 0.23 1 PMID:24814884 -2.7.1.33 atp bacillus anthracis 1.5 1.5 1 PMID:19763307 -2.7.1.33 atp bacillus subtilis 2.12 2.12 1 PMID:15795230 -2.7.1.33 atp escherichia coli 1.14 0.6054999999999999 2 PMID:19307712 -2.7.1.33 atp helicobacter pylori 2.09 2.09 1 PMID:15795230 -2.7.1.33 atp mycobacterium tuberculosis 0.65 0.411 5 PMID:17679145;PMID:19307712;PMID:20451532 -2.7.1.33 atp picrophilus oshimae 0.718 0.718 1 PMID:19854913 -2.7.1.33 atp staphylococcus aureus 1.6 1.6 1 PMID:15548531 -2.7.1.33 ctp bacillus anthracis 1.5 1.5 1 PMID:19763307 -2.7.1.33 datp bacillus anthracis 0.9 0.9 1 PMID:19763307 -2.7.1.33 dctp bacillus anthracis 0.5 0.5 1 PMID:19763307 -2.7.1.33 dgtp bacillus anthracis 0.8 0.8 1 PMID:19763307 -2.7.1.33 dttp bacillus anthracis 0.4 0.4 1 PMID:19763307 -2.7.1.33 gtp mycobacterium tuberculosis 0.064 0.064 1 PMID:20451532 -2.7.1.33 n-[(2r)-2,4-dihydroxy-3,3-dimethylbutanoyl]-beta-alanyl-n-pentylglycinamide escherichia coli 1.12 1.12 1 PMID:24814884 -2.7.1.33 n-heptylpantothenamide staphylococcus aureus 0.425 0.425 1 PMID:15548531 -2.7.1.33 n-pentylpantothenamide staphylococcus aureus 0.15 0.15 1 PMID:15548531 -2.7.1.33 pantheteine escherichia coli 1.03 1.03 1 PMID:24814884 -2.7.1.33 pantothenate mycobacterium tuberculosis 0.62 0.615 2 PMID:17679145 -2.7.1.33 pantothenate picrophilus oshimae 0.818 0.818 1 PMID:19854913 -2.7.1.33 pantothenol mycobacterium tuberculosis 0.4 0.39 2 PMID:17679145 -2.7.1.33 utp bacillus anthracis 1.7 1.7 1 PMID:19763307 -2.7.1.35 4'-deoxypyridoxine homo sapiens 2.94 2.2375 2 PMID:17250738 -2.7.1.35 4'-o-methylpyridoxine homo sapiens 0.46 0.46 1 PMID:17250738 -2.7.1.35 4-amino-5-hydroxymethyl-2-methylpyrimidine bacillus subtilis 0.36 0.36 1 PMID:14973012 -2.7.1.35 4-amino-5-hydroxymethyl-2-methylpyrimidine staphylococcus aureus 0.045 0.045 1 PMID:24601602 -2.7.1.35 atp bombyx mori 1.23 1.23 1 * -2.7.1.35 atp homo sapiens 1.9 1.435 2 PMID:23860900;PMID:31578392 -2.7.1.35 atp leishmania donovani 1.02 1.02 1 PMID:30031075 -2.7.1.35 atp pseudomonas aeruginosa 3.3 3.3 1 PMID:27425248 -2.7.1.35 atp salmonella enterica subsp. enterica serovar typhimurium 0.107 0.10200000000000001 2 PMID:31116912 -2.7.1.35 ginkgotoxin homo sapiens 0.46 0.46 1 PMID:17250738 -2.7.1.35 ginkgotoxin trypanosoma brucei 106.0 106.0 1 PMID:22857512 -2.7.1.35 pyridoxal bacillus subtilis 0.032 0.032 1 PMID:14973012 -2.7.1.35 pyridoxal bombyx mori 1.35 1.35 1 * -2.7.1.35 pyridoxal escherichia coli 2.3 2.15 2 PMID:15249053 -2.7.1.35 pyridoxal homo sapiens 6.08 0.97 11 PMID:15249053;PMID:17250738;PMID:17766369;PMID:19351586;PMID:23860900;PMID:25157434;PMID:31578392 -2.7.1.35 pyridoxal leishmania donovani 1.5 1.5 1 PMID:30031075 -2.7.1.35 pyridoxal plasmodium falciparum 0.05 0.05 1 PMID:15590634 -2.7.1.35 pyridoxal plasmodium vivax 0.073 0.073 1 PMID:25157434 -2.7.1.35 pyridoxal pseudomonas aeruginosa 1.3 1.3 1 PMID:27425248 -2.7.1.35 pyridoxal salmonella enterica subsp. enterica serovar typhimurium 0.107 0.107 1 PMID:31116912 -2.7.1.35 pyridoxal staphylococcus aureus 0.165 0.165 1 PMID:24601602 -2.7.1.35 pyridoxal trypanosoma brucei 131.0 65.7 2 PMID:22857512;PMID:9274862 -2.7.1.35 pyridoxal trypanosoma cruzi 0.015 0.015 1 PMID:25157434 -2.7.1.35 pyridoxamine escherichia coli 0.7 0.55 2 PMID:15249053 -2.7.1.35 pyridoxamine homo sapiens 0.79 0.79 3 PMID:15249053;PMID:17250738 -2.7.1.35 pyridoxamine plasmodium falciparum 0.03 0.03 1 PMID:15590634 -2.7.1.35 pyridoxamine salmonella enterica subsp. enterica serovar typhimurium 0.097 0.097 1 PMID:31116912 -2.7.1.35 pyridoxamine trypanosoma brucei 127.0 127.0 1 PMID:22857512 -2.7.1.35 pyridoxine escherichia coli 0.3 0.3 1 PMID:15249053 -2.7.1.35 pyridoxine homo sapiens 6.08 0.7665000000000001 4 PMID:15249053;PMID:17250738 -2.7.1.35 pyridoxine plasmodium falciparum 0.11 0.11 1 PMID:15590634 -2.7.1.35 pyridoxine staphylococcus aureus 0.016 0.016 1 PMID:24601602 -2.7.1.35 pyridoxine trypanosoma brucei 122.0 122.0 1 PMID:22857512 -2.7.1.36 (r)-mevalonate bacopa monnieri 143.8 143.8 1 PMID:25281875 -2.7.1.36 (r)-mevalonate methanocaldococcus jannaschii 28.5 28.5 1 PMID:17964869 -2.7.1.36 (r)-mevalonate methanosarcina mazei 4.3 4.3 1 PMID:21908638 -2.7.1.36 (r)-mevalonate rattus norvegicus 21.9 21.9 1 PMID:17964869 -2.7.1.36 atp aedes aegypti 10.1 10.1 1 PMID:26566274 -2.7.1.36 atp bacopa monnieri 150.9 150.9 1 PMID:25281875 -2.7.1.39 atp schizosaccharomyces pombe 40.8 27.5 2 PMID:14759741;PMID:21538764 -2.7.1.39 d-homoserine escherichia coli 3.3 3.3 1 PMID:8973190 -2.7.1.39 l-2-amino-1,4-butanediol escherichia coli 2.0 2.0 1 PMID:8973190 -2.7.1.39 l-2-amino-5-hydroxyvalerate escherichia coli 2.5 2.5 1 PMID:8973190 -2.7.1.39 l-aspartate beta-semialdehyde escherichia coli 2.1 2.1 1 PMID:8973190 -2.7.1.39 l-homoserine escherichia coli 18.3 18.3 1 PMID:8973190 -2.7.1.39 l-homoserine methanocaldococcus jannaschii 0.75 0.75 1 PMID:19531469 -2.7.1.39 l-homoserine schizosaccharomyces pombe 40.2 25.700000000000003 2 PMID:14759741;PMID:21538764 -2.7.1.39 l-homoserine ethyl ester escherichia coli 13.6 13.6 1 PMID:8973190 -2.7.1.39 l-homoserine isobutyl ester escherichia coli 16.4 16.4 1 PMID:8973190 -2.7.1.39 l-homoserine isopropyl ester escherichia coli 13.6 13.6 1 PMID:8973190 -2.7.1.39 l-homoserine methyl ester escherichia coli 14.7 14.7 1 PMID:8973190 -2.7.1.39 l-homoserine n-butyl ester escherichia coli 29.1 29.1 1 PMID:8973190 -2.7.1.39 l-homoserine n-propyl ester escherichia coli 14.0 14.0 1 PMID:8973190 -2.7.1.4 atp arabidopsis thaliana 14.3 11.1 7 PMID:28441933 -2.7.1.4 d-fructose arabidopsis thaliana 14.3 11.1 7 PMID:28441933 -2.7.1.4 d-fructose entamoeba histolytica 14.3 14.3 1 PMID:25700717 -2.7.1.4 d-fructose zea mays 8897.0 4695.5 2 * -2.7.1.40 adp arabidopsis thaliana 6.68 3.05 5 PMID:32168758 -2.7.1.40 adp corynebacterium glutamicum 4.36 4.36 1 PMID:27852252 -2.7.1.40 adp saccharolobus solfataricus 80.29 55.815 4 * -2.7.1.40 adp thermofilum pendens 0.2 0.18 2 PMID:25811853 -2.7.1.40 adp toxoplasma gondii 47.6 47.6 1 PMID:18326043 -2.7.1.40 adp urocitellus richardsonii 360.0 56.0 3 PMID:28918505 -2.7.1.40 gdp toxoplasma gondii 110.0 110.0 1 PMID:18326043 -2.7.1.40 idp toxoplasma gondii 131.0 131.0 1 PMID:18326043 -2.7.1.40 phosphoenolpyruvate arabidopsis thaliana 6.68 3.05 5 PMID:32168758 -2.7.1.40 phosphoenolpyruvate corynebacterium glutamicum 5.58 5.58 1 PMID:27852252 -2.7.1.40 phosphoenolpyruvate entamoeba histolytica 9.79 9.79 1 PMID:31676451 -2.7.1.40 phosphoenolpyruvate geobacillus stearothermophilus 3204.0 3204.0 1 PMID:15749828 -2.7.1.40 phosphoenolpyruvate homo sapiens 1182.0 592.6 2 PMID:16147999 -2.7.1.40 phosphoenolpyruvate saccharolobus solfataricus 73.04 54.26 4 * -2.7.1.40 phosphoenolpyruvate saccharomyces cerevisiae 232.0 146.0 4 PMID:15568816 -2.7.1.40 phosphoenolpyruvate thermofilum pendens 1.0 0.69 2 PMID:25811853 -2.7.1.40 phosphoenolpyruvate trypanosoma brucei brucei 185.0 152.0 3 PMID:32084384 -2.7.1.40 phosphoenolpyruvate trypanosoma congolense 111.5 107.33 3 PMID:32084384 -2.7.1.40 phosphoenolpyruvate urocitellus richardsonii 360.0 56.0 3 PMID:28918505 -2.7.1.43 atp arabidopsis thaliana 8.5 8.5 1 PMID:19951951 -2.7.1.43 d-glucuronic acid arabidopsis thaliana 8.3 8.3 1 PMID:19951951 -2.7.1.45 2-dehydro-3-deoxy-d-gluconate sulfurisphaera tokodaii 8.26 8.26 2 PMID:17407821 -2.7.1.45 2-dehydro-3-deoxy-d-gluconate thermus thermophilus 11.0 11.0 1 PMID:15210349 -2.7.1.45 2-keto-d-gluconate sulfurisphaera tokodaii 26.3 26.3 2 PMID:17407821 -2.7.1.45 2-keto-d-gluconate thermus thermophilus 2.2 2.2 1 PMID:15210349 -2.7.1.48 cytidine homo sapiens 4.3 3.75 2 PMID:19532987;PMID:28955773 -2.7.1.48 cytidine thermus thermophilus 4.1 2.05205 2 PMID:21539325;PMID:28955773 -2.7.1.48 uridine homo sapiens 5.2 5.2 1 PMID:28955773 -2.7.1.49 2-methyl-4-amino-5-hydroxymethylpyrimidine escherichia coli 0.43 0.43 1 * -2.7.1.49 2-methyl-4-amino-5-hydroxymethylpyrimidine plasmodium falciparum 0.07 0.07 1 PMID:16497163 -2.7.1.49 4-amino-5-hydroxymethyl-2-methylpyrimidine escherichia coli 0.285 0.285 1 PMID:28729425 -2.7.1.49 4-amino-5-hydroxymethyl-2-methylpyrimidine staphylococcus aureus 0.045 0.045 1 PMID:24601602 -2.7.1.49 atp escherichia coli 0.43 0.43 1 * -2.7.1.49 pyridoxal staphylococcus aureus 0.165 0.165 1 PMID:24601602 -2.7.1.49 pyridoxine escherichia coli 0.36 0.36 1 * -2.7.1.49 pyridoxine staphylococcus aureus 0.016 0.016 1 PMID:24601602 -2.7.1.50 1,3,5-trimethyl-4-(2-hydroxyethyl)pyrazole staphylococcus aureus 3.58 3.58 1 PMID:26960569 -2.7.1.50 2-methyl-3-(2-hydroxyethyl)imidazole staphylococcus aureus 3.63 3.63 1 PMID:26960569 -2.7.1.50 4-methyl-5-(2-hydroxyethyl)thiazole staphylococcus aureus 2.28 2.28 1 PMID:26960569 -2.7.1.52 atp arabidopsis thaliana 0.38 0.38 1 PMID:18199744 -2.7.1.52 atp vitis vinifera 0.22 0.22 1 PMID:22949207 -2.7.1.52 l-fucose arabidopsis thaliana 0.34 0.34 1 PMID:18199744 -2.7.1.52 l-fucose bacteroides fragilis 0.39 0.39 1 PMID:30242642 -2.7.1.52 l-fucose mortierella alpina 23.35 23.35 1 PMID:26957583 -2.7.1.52 l-galactose bacteroides fragilis 0.195 0.195 1 * -2.7.1.59 atp arabidopsis thaliana 1.586 1.586 1 PMID:26408204 -2.7.1.59 d-glucose arabidopsis thaliana 6.69 6.69 1 PMID:26408204 -2.7.1.59 n-acetyl-d-galactosamine arabidopsis thaliana 0.161 0.161 1 PMID:26408204 -2.7.1.59 n-acetyl-d-glucosamine arabidopsis thaliana 4.347 4.347 1 PMID:26408204 -2.7.1.59 n-acetyl-d-glucosamine candida albicans 0.03 0.03 1 PMID:11298769 -2.7.1.59 n-acetyl-d-glucosamine clostridium acetobutylicum 65.0 65.0 1 PMID:21784936 -2.7.1.59 n-acetyl-d-glucosamine homo sapiens 0.0325 0.0325 1 PMID:11298769 -2.7.1.6 2-amino-deoxy-d-galactose escherichia coli 0.195 0.195 1 PMID:12816414 -2.7.1.6 2-deoxy-d-galactose escherichia coli 0.5 0.5 1 PMID:12816414 -2.7.1.6 2-deoxy-d-galactose homo sapiens 6.8 6.8 1 PMID:29505688;PMID:30253338 -2.7.1.6 2-deoxy-d-galactose saccharomyces cerevisiae 4.01 3.57 2 PMID:16603548 -2.7.1.6 3-deoxy-3-methyl-d-galactose escherichia coli 0.085 0.085 1 PMID:12816414 -2.7.1.6 6-deoxy-d-galactose escherichia coli 0.0483 0.0483 1 PMID:12816414 -2.7.1.6 alpha-d-galactose homo sapiens 1.7 1.7 3 PMID:27789348;PMID:29505688;PMID:30253338 -2.7.1.6 alpha-d-galactose lactococcus lactis 11.0 11.0 1 PMID:23872454 -2.7.1.6 alpha-d-galactose leminorella grimontii 3.7 3.7 1 PMID:29193544 -2.7.1.6 alpha-d-galactose rattus norvegicus 0.65 0.65 1 PMID:19433218 -2.7.1.6 alpha-d-galactose streptomyces coelicolor 1.35 1.35 1 PMID:30593944 -2.7.1.6 atp bifidobacterium longum subsp. infantis 146.0 146.0 1 PMID:22633137 -2.7.1.6 atp homo sapiens 8.7 2.0 9 PMID:12694189;PMID:27789348;PMID:29505688;PMID:30253338 -2.7.1.6 atp leminorella grimontii 21.3 21.3 1 PMID:29193544 -2.7.1.6 atp pyrococcus horikoshii 0.91 0.91 1 PMID:16511293 -2.7.1.6 atp saccharomyces cerevisiae 55.8 55.8 1 PMID:14144 -2.7.1.6 atp streptomyces coelicolor 1.35 1.35 1 PMID:30593944 -2.7.1.6 d-galactosamine homo sapiens 2.1 1.9 2 PMID:29505688;PMID:30253338 -2.7.1.6 d-galactose bifidobacterium longum subsp. infantis 146.0 146.0 1 PMID:22633137 -2.7.1.6 d-galactose homo sapiens 8.7 8.7 2 PMID:12694189;PMID:14596685 -2.7.1.6 d-galactose pyrococcus horikoshii 0.91 0.91 1 PMID:16511293 -2.7.1.6 d-galactose saccharomyces cerevisiae 55.8 39.05 2 PMID:14144;PMID:16603548 -2.7.1.6 d-galactose streptococcus pneumoniae 2.61 2.61 1 PMID:22513283 -2.7.1.6 d-galactose trypanosoma cruzi 0.38 0.38 1 PMID:27312997 -2.7.1.6 d-glucose saccharomyces cerevisiae 0.034 0.034 1 PMID:16603548 -2.7.1.6 d-glucose streptococcus pneumoniae 1.1 1.1 1 PMID:22513283 -2.7.1.6 d-talose homo sapiens 2.0 1.85 2 PMID:29505688;PMID:30253338 -2.7.1.6 n-acetyl-d-galactosamine streptococcus pneumoniae 0.36 0.36 1 PMID:22513283 -2.7.1.60 atp staphylococcus aureus 262.6 262.6 1 PMID:31949045 -2.7.1.60 d-glucose staphylococcus aureus 60.0 60.0 1 PMID:31949045 -2.7.1.60 n-acetyl-d-glucosamine staphylococcus aureus 23.4 23.4 1 PMID:31949045 -2.7.1.60 n-acetyl-d-mannosamine staphylococcus aureus 262.6 262.6 1 PMID:31949045 -2.7.1.63 (phosphate)120 corynebacterium glutamicum 11.3 11.3 1 PMID:20379711 -2.7.1.63 (phosphate)15 corynebacterium glutamicum 6.0 6.0 1 PMID:20379711 -2.7.1.63 (phosphate)20 corynebacterium glutamicum 8.5 8.5 1 PMID:20379711 -2.7.1.63 (phosphate)25 corynebacterium glutamicum 10.0 10.0 1 PMID:20379711 -2.7.1.63 (phosphate)30 microlunatus phosphovorus 270.0 270.0 1 PMID:12949120 -2.7.1.63 (phosphate)31 propionibacterium freudenreichii subsp. shermanii 56.0 56.0 1 PMID:8639629 -2.7.1.63 (phosphate)35 acidipropionibacterium acidipropionici 55.0 55.0 1 PMID:10448674 -2.7.1.63 (phosphate)35 mycobacterium tuberculosis 196.0 196.0 1 PMID:10448674 -2.7.1.63 (phosphate)35 propionibacterium freudenreichii subsp. shermanii 57.0 57.0 1 PMID:10448674 -2.7.1.63 (phosphate)4 corynebacterium glutamicum 2.5 2.5 1 PMID:20379711 -2.7.1.63 (phosphate)400 acidipropionibacterium acidipropionici 41.0 41.0 1 PMID:10448674 -2.7.1.63 (phosphate)400 mycobacterium tuberculosis 163.0 163.0 1 PMID:10448674 -2.7.1.63 (phosphate)400 propionibacterium freudenreichii subsp. shermanii 371.0 371.0 1 PMID:10448674 -2.7.1.63 (phosphate)45 corynebacterium glutamicum 8.3 8.3 1 PMID:20379711 -2.7.1.63 (phosphate)45 methylomonas methanica 0.0068 0.0068 1 PMID:30769875 -2.7.1.63 (phosphate)45 nostoc sp. 48.2 48.2 1 PMID:25320362 -2.7.1.63 (phosphate)5 corynebacterium glutamicum 0.2 0.2 1 PMID:20379711 -2.7.1.63 (phosphate)6 streptomyces coelicolor 0.31 0.31 1 PMID:24200789 -2.7.1.63 (phosphate)65 corynebacterium glutamicum 11.6 11.6 1 PMID:20379711 -2.7.1.63 (phosphate)700 microlunatus phosphovorus 183.0 183.0 1 PMID:12949120 -2.7.1.63 (phosphate)75 corynebacterium glutamicum 15.4 15.4 1 PMID:20379711 -2.7.1.63 (phosphate)8 microlunatus phosphovorus 87.0 87.0 1 PMID:12949120 -2.7.1.63 (phosphate)n anabaena sp. 48.2 48.2 1 PMID:25320362 -2.7.1.63 (phosphate)n streptomyces coelicolor 0.3 0.3 1 PMID:24200789 -2.7.1.63 atp acidipropionibacterium acidipropionici 63.0 63.0 1 PMID:10448674 -2.7.1.63 atp corynebacterium glutamicum 0.4 0.4 1 PMID:20379711 -2.7.1.63 atp mycobacterium tuberculosis 116.0 112.0 2 PMID:8703950 -2.7.1.63 atp propionibacterium freudenreichii subsp. shermanii 25.0 25.0 1 PMID:8639629 -2.7.1.63 ctp corynebacterium glutamicum 0.1 0.1 1 PMID:20379711 -2.7.1.63 ctp propionibacterium freudenreichii subsp. shermanii 7.4 7.4 1 PMID:8639629 -2.7.1.63 d-glucose anabaena sp. 48.2 48.2 1 PMID:25320362 -2.7.1.63 d-glucose methylomonas methanica 0.0066 0.0066 1 PMID:30769875 -2.7.1.63 d-glucose streptomyces coelicolor 0.3 0.275 2 PMID:24200789 -2.7.1.63 d-glucose thermobifida fusca 136.0 94.75 6 PMID:21766194 -2.7.1.63 d-mannose nostoc sp. 0.21 0.21 1 PMID:25320362 -2.7.1.63 datp propionibacterium freudenreichii subsp. shermanii 14.0 14.0 1 PMID:8639629 -2.7.1.63 glucose mycobacterium tuberculosis 116.0 112.0 2 PMID:8703950 -2.7.1.63 gtp corynebacterium glutamicum 1.3 1.3 1 PMID:20379711 -2.7.1.63 gtp propionibacterium freudenreichii subsp. shermanii 11.0 11.0 1 PMID:8639629 -2.7.1.63 itp corynebacterium glutamicum 3.3 3.3 1 PMID:20379711 -2.7.1.63 mannose anabaena sp. 0.21 0.21 1 PMID:25320362 -2.7.1.63 utp corynebacterium glutamicum 0.3 0.3 1 PMID:20379711 -2.7.1.63 utp propionibacterium freudenreichii subsp. shermanii 7.0 7.0 1 PMID:8639629 -2.7.1.64 d-allose thermococcus kodakarensis 18.3 18.3 1 PMID:23737529 -2.7.1.64 d-lyxose thermococcus kodakarensis 3.9 3.9 1 PMID:23737529 -2.7.1.64 d-ribose thermococcus kodakarensis 5.1 5.1 1 PMID:23737529 -2.7.1.64 d-tagatose thermococcus kodakarensis 1.5 1.5 1 PMID:23737529 -2.7.1.64 d-talose thermococcus kodakarensis 13.1 13.1 1 PMID:23737529 -2.7.1.64 d-xylose thermococcus kodakarensis 5.6 5.6 1 PMID:23737529 -2.7.1.64 d-xylulose thermococcus kodakarensis 11.6 11.6 1 PMID:23737529 -2.7.1.64 myo-inositol thermococcus kodakarensis 23.2 23.2 1 PMID:23737529 -2.7.1.66 atp streptococcus mutans 3.4 3.4 1 PMID:28872301 -2.7.1.66 undecaprenol streptococcus mutans 4.0 4.0 1 PMID:28872301 -2.7.1.67 1-phosphatidyl-1d-myo-inositol saccharomyces cerevisiae 2.77 2.77 1 PMID:2848810 -2.7.1.67 atp saccharomyces cerevisiae 2.77 2.77 1 PMID:2848810 -2.7.1.71 atp colwellia psychrerythraea 32.8 32.8 1 PMID:27666993 -2.7.1.71 atp dickeya chrysanthemi 35.0 35.0 1 PMID:11369852 -2.7.1.71 atp escherichia coli 122.51 122.51 1 PMID:27666993 -2.7.1.71 atp mycobacterium tuberculosis 60.0 60.0 1 PMID:23671579 -2.7.1.71 shikimate acinetobacter baumannii 21.4 21.4 1 PMID:26249354 -2.7.1.71 shikimate colwellia psychrerythraea 28.8 28.8 1 PMID:27666993 -2.7.1.71 shikimate dickeya chrysanthemi 35.0 35.0 1 PMID:11369852 -2.7.1.71 shikimate escherichia coli 55.86 55.86 1 PMID:27666993 -2.7.1.71 shikimate helicobacter pylori 0.116 0.116 1 PMID:27699905 -2.7.1.71 shikimate mycobacterium tuberculosis 295.0 177.5 2 PMID:23671579;PMID:27699905 -2.7.1.72 atp escherichia coli 1.7 1.7 1 PMID:24248535 -2.7.1.72 streptomycin escherichia coli 1.7 1.7 1 PMID:24248535 -2.7.1.74 (-)-beta-2',3'-dideoxy-3'-thiacytidine homo sapiens 0.102 0.066 2 PMID:17158155 -2.7.1.74 1-beta-d-arabinofuranosylcytosine homo sapiens 0.32 0.3 3 PMID:16401075;PMID:18258203 -2.7.1.74 1-beta-d-arabinosylcytosine homo sapiens 0.34 0.34 1 PMID:19159229 -2.7.1.74 2',2'-difluorodeoxycytidine homo sapiens 0.44 0.44 1 PMID:18258203 -2.7.1.74 2'-deoxyadenosine homo sapiens 3.1 1.9 8 PMID:16401075;PMID:18258203;PMID:18361501;PMID:18570408;PMID:19159229 -2.7.1.74 2'-deoxycytidine homo sapiens 0.11 0.04 5 PMID:15628745;PMID:16401075;PMID:18258203;PMID:19159229 -2.7.1.74 2'-deoxyguanosine homo sapiens 3.26 2.55 8 PMID:16401075;PMID:18258203;PMID:18361501;PMID:18570408;PMID:19159229 -2.7.1.74 2,5-difluoro-4-[1-(2-deoxy-beta-l-ribofuranosyl)]-aniline homo sapiens 0.02 0.02 1 PMID:15628745 -2.7.1.74 2-chlorodeoxyadenosine homo sapiens 0.6 0.485 2 PMID:18570408 -2.7.1.74 atp homo sapiens 0.4 0.0315 6 PMID:16401075;PMID:17158155 -2.7.1.74 cladribine homo sapiens 0.172 0.12619999999999998 2 PMID:22490700 -2.7.1.74 clofarabine homo sapiens 1.11 0.798 2 PMID:22490700 -2.7.1.74 cytarabine homo sapiens 0.38 0.38 1 PMID:26485161 -2.7.1.74 deoxyadenosine gallus gallus 4.07 4.07 1 PMID:27906638 -2.7.1.74 deoxyadenosine xenopus laevis 2.73 2.73 1 PMID:27906638 -2.7.1.74 deoxycytidine gallus gallus 0.05 0.05 1 PMID:27906638 -2.7.1.74 deoxycytidine homo sapiens 0.064 0.035 5 PMID:18361501;PMID:22490700;PMID:26485161 -2.7.1.74 deoxycytidine mus musculus 78300.0 39815.0 2 PMID:999281 -2.7.1.74 deoxycytidine xenopus laevis 0.09 0.09 1 PMID:27906638 -2.7.1.74 deoxyguanosine gallus gallus 1.23 1.23 1 PMID:27906638 -2.7.1.74 deoxyguanosine xenopus laevis 3.4 3.4 1 PMID:27906638 -2.7.1.74 deoxythymidine gallus gallus 1.08 1.08 1 PMID:27906638 -2.7.1.74 deoxythymidine xenopus laevis 0.29 0.29 1 PMID:27906638 -2.7.1.74 deoxyuridine gallus gallus 1.05 1.05 1 PMID:27906638 -2.7.1.74 deoxyuridine xenopus laevis 1.27 1.27 1 PMID:27906638 -2.7.1.74 fludarabine homo sapiens 1.334 0.7555000000000001 2 PMID:22490700 -2.7.1.74 gemcitabine homo sapiens 0.57 0.48 2 PMID:19159229;PMID:26485161 -2.7.1.74 thymidine homo sapiens 0.38 0.38 2 PMID:18361501 -2.7.1.74 troxacitabine homo sapiens 0.179 0.137 2 PMID:17158155 -2.7.1.74 utp homo sapiens 0.179 0.0755 4 PMID:17158155 -2.7.1.76 2',2'-difluorodeoxycytidine staphylococcus aureus 0.19 0.19 1 PMID:17526755 -2.7.1.76 2'-deoxyadenosine dictyostelium discoideum 3.7 3.7 1 PMID:17448496 -2.7.1.76 2'-deoxyadenosine staphylococcus aureus 1.82 1.82 1 PMID:17526755 -2.7.1.76 2'-deoxycytidine staphylococcus aureus 0.56 0.56 1 PMID:17526755 -2.7.1.76 2'-fluoro-arabinosyl adenine dictyostelium discoideum 3.3 3.3 1 PMID:17448496 -2.7.1.76 atp mycoplasma mycoides 0.84 0.84 1 PMID:11737647 -2.7.1.76 ctp mycoplasma mycoides 0.62 0.62 1 PMID:11737647 -2.7.1.76 deoxyadenosine bacillus cereus 1.22 1.22 1 PMID:17615154 -2.7.1.76 deoxyadenosine dictyostelium discoideum 3.7 3.7 1 PMID:17448496 -2.7.1.76 deoxyadenosine mycoplasma mycoides 1.48 1.48 1 PMID:11737647 -2.7.1.76 deoxycytidine bacillus cereus 0.55 0.55 1 PMID:17615154 -2.7.1.76 deoxycytidine mycoplasma mycoides 1.23 1.23 1 PMID:11737647 -2.7.1.76 deoxyguanosine mycoplasma mycoides 0.61 0.61 1 PMID:11737647 -2.7.1.76 fludarabine dictyostelium discoideum 3.3 3.3 1 PMID:17448496 -2.7.1.76 gemcitabine bacillus cereus 0.17 0.17 1 PMID:17615154 -2.7.1.76 thymidine dictyostelium discoideum 8.1 4.05405 2 PMID:17448496 -2.7.1.76 ttp mycoplasma mycoides 1.64 1.64 1 PMID:11737647 -2.7.1.76 utp mycoplasma mycoides 0.36 0.36 1 PMID:11737647 -2.7.1.77 1-naphthyl phosphate hordeum vulgare 2.6 2.6 1 PMID:3013235 -2.7.1.77 2-naphthyl phosphate hordeum vulgare 30.0 30.0 1 PMID:3013235 -2.7.1.77 3'-amp hordeum vulgare 6.8 6.8 1 PMID:3013235 -2.7.1.77 3'-ump hordeum vulgare 12.0 12.0 1 PMID:3013235 -2.7.1.77 4-nitrophenyl phosphate hordeum vulgare 77.0 77.0 1 PMID:3013235 -2.7.1.77 5'-amp hordeum vulgare 41.0 41.0 1 PMID:3013235 -2.7.1.77 5'-ump hordeum vulgare 67.0 67.0 1 PMID:3013235 -2.7.1.77 adenosine-5'-phosphorothionate hordeum vulgare 0.4 0.4 1 PMID:3013235 -2.7.1.78 3'-cmp kostyavirus cjw1 0.008 0.008 1 PMID:15056675 -2.7.1.78 3'-cmp omegavirus omega 1.6 1.6 1 PMID:15056675 -2.7.1.78 5'-dephospho-gaaaa-rna caenorhabditis elegans 2.6 2.6 1 PMID:24813946 -2.7.1.78 5'-dephospho-gc-rna caenorhabditis elegans 2.9 2.9 1 PMID:24813946 -2.7.1.78 5'-ho-ccgaccaacgaaggt acetivibrio thermocellus 0.072 0.072 1 PMID:23721485 -2.7.1.78 5'-oh dna pyrococcus horikoshii 0.077 0.077 1 PMID:19299550 -2.7.1.78 5'-phospho-dna pyrococcus horikoshii 0.00083 0.00083 1 PMID:19299550 -2.7.1.78 [gamma-s]atp synthetic ribozyme 0.00283 0.00283 1 PMID:7578148 -2.7.1.78 atp caenorhabditis elegans 2.9 2.9 1 PMID:24813946 -2.7.1.78 atp kostyavirus cjw1 0.0043 0.0043 1 PMID:15056675 -2.7.1.78 atp omegavirus omega 0.2 0.2 1 PMID:15056675 -2.7.1.78 atp runella slithyformis 0.183 0.183 1 PMID:27895092 -2.7.1.78 atp synthetic ribozyme 5e-05 5e-05 1 PMID:7578148 -2.7.1.78 atp unidentified baculovirus 0.023 0.023 1 PMID:14747466 -2.7.1.78 gggcc(ag)10ggccc-fluorescein tequatrovirus t4 198.0 198.0 1 PMID:19170527 -2.7.1.78 r(a20) rhodothermus phage rm378 2.6 2.25 2 PMID:15579472 -2.7.1.82 ethanolamine homo sapiens 0.00016 0.00016 1 PMID:2167130 -2.7.1.82 ethanolamine trypanosoma brucei 12.9 9.73 2 PMID:18489261 -2.7.1.83 pseudouridine arabidopsis thaliana 0.23 0.23 1 PMID:31907295 -2.7.1.86 atp fusarium oxysporum 0.84 0.84 1 * -2.7.1.86 nad+ saccharomyces cerevisiae 7.4 7.4 1 PMID:21730068 -2.7.1.86 nadh fusarium oxysporum 0.95 0.95 1 * -2.7.1.86 nadh saccharomyces cerevisiae 16.1 16.1 1 PMID:21730068 -2.7.1.90 d-fructose 6-phosphate acetivibrio thermocellus 127.0 127.0 1 PMID:31871051 -2.7.1.90 d-fructose 6-phosphate clostridium thermosuccinogenes 182.0 182.0 1 PMID:31871051 -2.7.1.90 d-fructose 6-phosphate entamoeba histolytica 330.0 327.5 2 PMID:10900132;PMID:9753654 -2.7.1.90 diphosphate entamoeba histolytica 330.0 330.0 1 PMID:10900132 -2.7.1.90 diphosphate giardia duodenalis 83.0 83.0 2 PMID:8577346 -2.7.1.90 phosphate giardia duodenalis 83.0 83.0 3 PMID:8577346 -2.7.1.90 sedoheptulose 7-phosphate acetivibrio thermocellus 80.0 80.0 1 PMID:31871051 -2.7.1.90 sedoheptulose 7-phosphate clostridium thermosuccinogenes 49.0 49.0 1 PMID:31871051 -2.7.1.91 atp homo sapiens 7.0 0.53 3 PMID:23602659;PMID:26426296 -2.7.1.95 atp enterococcus casseliflavus 1.59 1.59 1 PMID:20231391 -2.7.1.95 atp escherichia coli 1.76 0.935 2 PMID:8679630 -2.7.1.95 kanamycin a escherichia coli 1.79 1.79 1 PMID:8679630 -2.7.10.2 [kdsrc kinase]-l-tyrosine homo sapiens 1.88 1.39 2 PMID:12686554;PMID:14657361 -2.7.10.2 atp homo sapiens 55.0 3.52 3 PMID:17144667;PMID:18762159 -2.7.10.2 atp monosiga brevicollis 0.37 0.37 1 PMID:26090675 -2.7.10.2 eeeey homo sapiens 2.27 2.27 1 PMID:17144667 -2.7.10.2 eeeeyiq[dp]-8-hydroxy-5-(n,n-dimethylsulfonamido)-2-methylquinoline-g homo sapiens 396.0 396.0 1 PMID:18762159 -2.7.10.2 poly(glu4-tyr) homo sapiens 1.49 1.03 2 PMID:12686554;PMID:14657361 -2.7.10.3 atp gallus gallus 3.52 3.52 1 PMID:17144667 -2.7.10.3 l-tyrosine in poly(glu,tyr) myxococcus xanthus 0.0003 0.0003 1 PMID:25998248 -2.7.10.3 l-tyrosyl-[aavheylsa] burkholderia cepacia 0.0009 0.0009 1 PMID:34439861 -2.7.10.3 polye4y gallus gallus 2.27 2.27 1 PMID:17144667 -2.7.10.4 [src]-(l-tyrosine) homo sapiens 2.27 1.88 3 PMID:19244618 -2.7.10.4 kkkkeeiyfff homo sapiens 3.33 3.25 2 PMID:9425036 -2.7.10.4 poly(glu-tyr) homo sapiens 0.67 0.3385 2 PMID:10460171 -2.7.11.1 atp aquifex aeolicus 0.00016 0.00016 1 PMID:18270660 -2.7.11.1 gtp aquifex aeolicus 6e-05 6e-05 1 PMID:18270660 -2.7.11.11 atp homo sapiens 6.03 6.03 1 PMID:29632813 -2.7.11.11 atp mus musculus 19.6 19.6 1 PMID:17242405 -2.7.11.11 kemptide homo sapiens 14.5 14.5 1 PMID:29632813 -2.7.11.11 leu-arg-arg-ala-ser-leu-gly mus musculus 19.0 19.0 1 PMID:22617327 -2.7.11.14 rhodopsin homo sapiens 1.2 1.1 2 PMID:15946941 -2.7.11.15 atp bos taurus 0.0029 0.0029 1 PMID:16081410 -2.7.11.17 atp homo sapiens 9.9 4.6 6 PMID:21081101;PMID:32198047 -2.7.11.17 biotinylated thr-arg-ser-ala-ile-arg-arg-ala-ser-thr-ile-glu-met-pro-gln-gln-ala-arg-gln homo sapiens 9.9 8.9 4 PMID:21081101 -2.7.11.17 gst-tagged glun2a homo sapiens 0.33 0.33 1 PMID:32198047 -2.7.11.17 gst-tagged glun2b homo sapiens 0.16 0.16 1 PMID:32198047 -2.7.11.17 myelin basic protein rattus norvegicus 2.17 2.17 1 PMID:1846291 -2.7.11.18 [non-muscle heavy meromyosin iib] gallus gallus 8.0 8.0 1 PMID:27528075 -2.7.11.18 [non-muscle regulatory light chain] gallus gallus 12.6 12.6 1 PMID:27528075 -2.7.11.18 [smooth muscle heavy meromyosin] gallus gallus 12.8 12.8 1 PMID:27528075 -2.7.11.18 [smooth muscle regulatory light chain] gallus gallus 28.6 28.6 1 PMID:27528075 -2.7.11.18 myosin light chain homo sapiens 5.17 5.17 1 PMID:156362 -2.7.11.18 myosin light chain oryctolagus cuniculus 88.0 19.0 3 PMID:6547715 -2.7.11.18 unphosphorylated myosin ii regulatory light chain mus musculus 0.3 0.3 1 PMID:12802051 -2.7.11.19 atp oryctolagus cuniculus 97.0 97.0 1 PMID:19141288 -2.7.11.19 glycogen phosphorylase b oryctolagus cuniculus 134.0 134.0 1 PMID:19141288 -2.7.11.19 melittin oryctolagus cuniculus 0.0983 0.0983 1 PMID:8218258 -2.7.11.19 phosphorylase b oryctolagus cuniculus 104.0 95.2 4 PMID:6279620;PMID:8218258 -2.7.11.19 tetradecapeptide oryctolagus cuniculus 23.6 23.6 1 PMID:8218258 -2.7.11.2 [pyruvate dehydrogenase (lipoamide)] rattus norvegicus 0.277 0.108 5 PMID:11486000 -2.7.11.2 atp bos taurus 0.533 0.5225 2 PMID:3004826;PMID:3700404 -2.7.11.2 atp homo sapiens 4.7 0.91 7 PMID:15491150 -2.7.11.2 pyruvate dehydrogenase arabidopsis thaliana 0.55 0.55 1 PMID:15629119 -2.7.11.2 pyruvate dehydrogenase homo sapiens 0.0032 0.0023 2 PMID:15169745 -2.7.11.21 atp danio rerio 0.01311 0.0077 2 PMID:18703838 -2.7.11.21 atp homo sapiens 0.01386 0.0041 3 PMID:17461553;PMID:18703838 -2.7.11.21 cdc25c homo sapiens 0.0094 0.0094 2 PMID:17461553 -2.7.11.22 adaqhatppkkkrkvedpkdf saccharomyces cerevisiae 3.15 2.525 2 PMID:15744308 -2.7.11.22 atp homo sapiens 0.28 0.28 1 PMID:18636751 -2.7.11.22 fin1 saccharomyces cerevisiae 1.7 1.7 1 PMID:15744308 -2.7.11.24 atf2delta109 mus musculus 4.7 4.25 2 PMID:18669639 -2.7.11.24 egf receptor peptide mus musculus 31.6 19.295 2 PMID:18669639 -2.7.11.24 elkerk synthetic construct 2.3 2.3 1 PMID:17918909 -2.7.11.24 erkmek1 synthetic construct 2.83 2.83 1 PMID:17918909 -2.7.11.24 erkmek2 synthetic construct 3.0 3.0 1 PMID:17918909 -2.7.11.24 erkste7 synthetic construct 2.67 2.67 1 PMID:17918909 -2.7.11.24 erksub synthetic construct 9.5 4.167 3 PMID:17918909 -2.7.11.24 mek1erk synthetic construct 9.5 5.75 2 PMID:17918909 -2.7.11.24 mek2erk synthetic construct 16.67 2.3 3 PMID:17918909 -2.7.11.24 protein atf2 homo sapiens 0.98 0.98 1 PMID:15582552 -2.7.11.24 scrammmek2 synthetic construct 2.94 2.5534999999999997 2 PMID:17918909 -2.7.11.24 ste7erk synthetic construct 2.83 2.83 1 PMID:17918909 -2.7.11.25 atp homo sapiens 0.26 0.0329 6 PMID:16087150 -2.7.11.25 mek homo sapiens 0.26 0.0329 6 PMID:16087150 -2.7.11.39 [s6 peptide]-l-serine homo sapiens 1.52 1.52 1 PMID:12102637 -2.7.11.4 phosphate rattus norvegicus 0.475 0.2646 2 PMID:7649998 -2.7.11.7 akrvsmmr dictyostelium discoideum 5.4 5.2 2 PMID:9774403 -2.7.11.7 atp dictyostelium discoideum 0.1 0.1 1 PMID:26260792 -2.7.11.7 grgrssvys acanthamoeba castellanii 71.0 71.0 1 PMID:9539704 -2.7.11.7 grsarvstya dictyostelium discoideum 4.7 4.6 3 PMID:9774403 -2.7.11.7 rkkfgesektktkefl-amide dictyostelium discoideum 0.79 0.55 3 PMID:11278493 -2.7.11.7 yaydtryrr dictyostelium discoideum 14.0 14.0 1 PMID:11278493 -2.7.12.1 atp arachis hypogaea 5.25 5.25 1 PMID:12624102 -2.7.12.2 atp homo sapiens 0.085 0.085 1 PMID:22178908 -2.7.12.2 erk2 homo sapiens 0.503 0.503 1 PMID:22178908 -2.7.12.2 k52r-[erk2] homo sapiens 0.074 0.074 1 PMID:22178908 -2.7.12.2 k53m-[p38alpha] homo sapiens 0.152 0.152 1 PMID:22178908 -2.7.12.2 p38alpha homo sapiens 0.243 0.243 1 PMID:22178908 -2.7.2.1 acetate cereibacter sphaeroides 177.0 177.0 1 PMID:33040182 -2.7.2.1 acetate clostridium acetobutylicum 280.0 280.0 1 PMID:9082921 -2.7.2.1 acetate escherichia coli 1420.0 962.5 4 PMID:24801996 -2.7.2.1 acetate lactococcus lactis 761.0 420.5 2 PMID:24464460 -2.7.2.1 acetate methanosarcina thermophila 1042.0 915.5 2 PMID:28724909 -2.7.2.1 acetate methylotuvimicrobium alcaliphilum 233.0 233.0 1 PMID:26275877 -2.7.2.1 acetate salmonella enterica subsp. enterica serovar typhimurium 1180.0 545.0 3 PMID:23031654;PMID:26448059 -2.7.2.1 acetate shewanella sp. 385.0 272.5 4 PMID:24801996 -2.7.2.1 acetyl phosphate acholeplasma laidlawii 875.0 875.0 1 PMID:217865 -2.7.2.1 acetyl phosphate clostridium acetobutylicum 700.0 700.0 1 PMID:9082921 -2.7.2.1 acetyl phosphate escherichia coli 3600.0 1850.0 4 PMID:24801996 -2.7.2.1 acetyl phosphate lactococcus lactis 1105.0 599.0 2 PMID:24464460 -2.7.2.1 acetyl phosphate methanosarcina thermophila 2680.0 2115.0 2 PMID:15774882;PMID:28724909 -2.7.2.1 acetyl phosphate methylotuvimicrobium alcaliphilum 3167.0 3167.0 1 PMID:26275877 -2.7.2.1 acetyl phosphate porphyromonas gingivalis 105.0 105.0 1 PMID:31007866 -2.7.2.1 acetyl phosphate salmonella enterica subsp. enterica serovar typhimurium 1764.0 1764.0 1 PMID:23031654 -2.7.2.1 acetyl phosphate shewanella sp. 2100.0 1520.0 4 PMID:24801996 -2.7.2.1 adp acholeplasma laidlawii 1000.0 318.0 3 PMID:217865 -2.7.2.1 adp clostridium acetobutylicum 532.0 532.0 1 PMID:9082921 -2.7.2.1 adp escherichia coli 3515.0 1871.5 4 PMID:24801996 -2.7.2.1 adp methanosarcina thermophila 1915.0 1260.0 3 PMID:15647264;PMID:17999468;PMID:28724909 -2.7.2.1 adp methylotuvimicrobium alcaliphilum 1.28 1.28 1 PMID:26275877 -2.7.2.1 adp porphyromonas gingivalis 1487.0 1487.0 1 PMID:31007866 -2.7.2.1 adp salmonella enterica subsp. enterica serovar typhimurium 1750.0 1750.0 1 PMID:23031654 -2.7.2.1 adp shewanella sp. 2135.0 1525.0 4 PMID:24801996 -2.7.2.1 atp acholeplasma laidlawii 268.0 268.0 1 PMID:217865 -2.7.2.1 atp cereibacter sphaeroides 250.0 250.0 1 PMID:33040182 -2.7.2.1 atp clostridium acetobutylicum 238.0 238.0 1 PMID:9082921 -2.7.2.1 atp escherichia coli 1500.0 908.0 5 PMID:24801996;PMID:24856051 -2.7.2.1 atp methanosarcina thermophila 1055.0 913.0 5 PMID:15647264;PMID:15774882;PMID:17999468;PMID:25775277;PMID:28724909 -2.7.2.1 atp methylotuvimicrobium alcaliphilum 2.36 2.36 1 PMID:26275877 -2.7.2.1 atp salmonella enterica subsp. enterica serovar typhimurium 1170.0 870.0 5 PMID:23031654;PMID:26448059 -2.7.2.1 atp shewanella sp. 350.0 270.0 4 PMID:24801996 -2.7.2.1 butyrate cereibacter sphaeroides 118.0 118.0 1 PMID:33040182 -2.7.2.1 butyrate methanosarcina thermophila 0.18 0.18 1 PMID:15774882 -2.7.2.1 ctp methanosarcina thermophila 460.0 460.0 1 PMID:25775277 -2.7.2.1 formate salmonella enterica subsp. enterica serovar typhimurium 880.0 880.0 1 PMID:23031654 -2.7.2.1 gtp methanosarcina thermophila 571.0 571.0 1 PMID:25775277 -2.7.2.1 isobutyrate cereibacter sphaeroides 65.4 65.4 1 PMID:33040182 -2.7.2.1 itp methanosarcina thermophila 742.0 742.0 1 PMID:25775277 -2.7.2.1 propionate cereibacter sphaeroides 172.0 172.0 1 PMID:33040182 -2.7.2.1 propionate methanosarcina thermophila 218.0 218.0 1 PMID:15774882 -2.7.2.1 propionate salmonella enterica subsp. enterica serovar typhimurium 940.0 940.0 1 PMID:23031654 -2.7.2.1 ttp methanosarcina thermophila 540.0 540.0 1 PMID:25775277 -2.7.2.1 utp methanosarcina thermophila 415.0 415.0 1 PMID:25775277 -2.7.2.1 valerate cereibacter sphaeroides 80.2 80.2 1 PMID:33040182 -2.7.2.11 atp leishmania donovani 11.7 11.7 1 PMID:29777624 -2.7.2.11 l-glutamate leishmania donovani 12.8 12.8 1 PMID:29777624 -2.7.2.12 acetate entamoeba histolytica 1.76 1.58 2 PMID:22903977;PMID:28724909 -2.7.2.12 acetyl phosphate entamoeba histolytica 1939.0 148.0 4 PMID:22903977;PMID:26922831;PMID:28724909 -2.7.2.12 butyrate entamoeba histolytica 0.33 0.33 1 PMID:22903977 -2.7.2.12 diphosphate entamoeba histolytica 2.6 1.75 2 PMID:24856051;PMID:28724909 -2.7.2.12 hexanoate entamoeba histolytica 0.051 0.051 1 PMID:22903977 -2.7.2.12 phosphate entamoeba histolytica 196.0 196.0 1 PMID:28724909 -2.7.2.12 propionate entamoeba histolytica 1.16 1.16 1 PMID:22903977 -2.7.2.12 valerate entamoeba histolytica 0.19 0.19 1 PMID:22903977 -2.7.2.15 acetate salmonella enterica subsp. enterica serovar typhimurium 120.0 120.0 1 PMID:23747922 -2.7.2.15 atp salmonella enterica subsp. enterica serovar typhimurium 120.0 120.0 1 PMID:23747922 -2.7.2.15 butyrate salmonella enterica subsp. enterica serovar typhimurium 60.0 60.0 1 PMID:23747922 -2.7.2.15 ctp salmonella enterica subsp. enterica serovar typhimurium 73.0 73.0 1 PMID:23747922 -2.7.2.15 gtp salmonella enterica subsp. enterica serovar typhimurium 113.0 113.0 1 PMID:23747922 -2.7.2.15 propanoate salmonella enterica subsp. enterica serovar typhimurium 108.0 108.0 1 PMID:23747922 -2.7.2.15 utp salmonella enterica subsp. enterica serovar typhimurium 81.0 81.0 1 PMID:23747922 -2.7.2.16 atp methanothermus fervidus 108.0 108.0 1 PMID:2226838 -2.7.2.18 acetate cereibacter sphaeroides 177.0 177.0 1 PMID:33040182 -2.7.2.18 atp cereibacter sphaeroides 250.0 250.0 1 PMID:33040182 -2.7.2.18 butyrate cereibacter sphaeroides 118.0 118.0 1 PMID:33040182 -2.7.2.18 isobutyrate cereibacter sphaeroides 65.4 65.4 1 PMID:33040182 -2.7.2.18 propionate cereibacter sphaeroides 172.0 172.0 1 PMID:33040182 -2.7.2.18 valerate cereibacter sphaeroides 80.2 80.2 1 PMID:33040182 -2.7.2.2 adp giardia duodenalis 319.0 319.0 1 PMID:20383005 -2.7.2.2 carbamate giardia duodenalis 43.0 43.0 1 PMID:20383005 -2.7.2.2 carbamoyl phosphate giardia duodenalis 319.0 319.0 1 PMID:20383005 -2.7.2.3 2'-dctp homo sapiens 4.0 4.0 1 PMID:15450940 -2.7.2.3 2'-dgtp homo sapiens 110.0 110.0 1 PMID:15450940 -2.7.2.3 3-phospho-d-glycerate chlamydomonas reinhardtii 84.7 56.6 2 PMID:25202015 -2.7.2.3 3-phospho-d-glycerate hippoglossus stenolepis 570.0 570.0 1 PMID:6982068 -2.7.2.3 3-phospho-d-glycerate homo sapiens 833.0 526.5 4 PMID:18358841;PMID:18540639;PMID:23231058;PMID:29995887 -2.7.2.3 3-phospho-d-glycerate methanothermus fervidus 339.0 239.85 10 PMID:7588750 -2.7.2.3 3-phospho-d-glycerate pseudomonas sp. 540.0 537.0 3 PMID:10753921 -2.7.2.3 3-phospho-d-glycerate pyrococcus woesei 916.0 372.15 10 PMID:7588750 -2.7.2.3 3-phospho-d-glycerate saccharomyces cerevisiae 354.0 354.0 1 PMID:10092885 -2.7.2.3 3-phospho-d-glyceroyl phosphate homo sapiens 2633.0 2631.5 2 PMID:18358841;PMID:18540639 -2.7.2.3 3-phosphoglycerate leishmania major 3.7 2.535 2 PMID:32196942 -2.7.2.3 adp homo sapiens 2633.0 2631.5 4 PMID:18358841;PMID:18540639;PMID:19530648 -2.7.2.3 adp saccharomyces cerevisiae 963.1 963.1 1 PMID:17045469 -2.7.2.3 atp chlamydomonas reinhardtii 83.4 55.95 2 PMID:25202015 -2.7.2.3 atp hippoglossus stenolepis 570.0 570.0 1 PMID:6982068 -2.7.2.3 atp homo sapiens 833.0 833.0 4 PMID:18358841;PMID:18540639;PMID:19530648 -2.7.2.3 atp leishmania major 3.5 2.45 2 PMID:32196942 -2.7.2.3 atp methanothermus fervidus 338.9 239.85 8 PMID:7588750 -2.7.2.3 atp pseudomonas sp. 519.0 500.0 3 PMID:10753921 -2.7.2.3 atp pyrococcus woesei 916.0 372.15 8 PMID:7588750 -2.7.2.3 atp saccharomyces cerevisiae 354.0 354.0 1 PMID:10092885 -2.7.2.3 ctp homo sapiens 10.0 10.0 1 PMID:15450940 -2.7.2.3 d-adp homo sapiens 200.0 200.0 1 PMID:21549713 -2.7.2.3 d-atp homo sapiens 500.0 500.0 1 PMID:15450940 -2.7.2.3 d-gtp homo sapiens 420.0 420.0 1 PMID:15450940 -2.7.2.3 l-adp homo sapiens 685.0 385.5 2 PMID:18096512;PMID:21549713 -2.7.2.3 l-atp homo sapiens 100.0 100.0 1 PMID:15450940 -2.7.2.3 l-gtp homo sapiens 120.0 120.0 1 PMID:15450940 -2.7.2.4 aspartate bacillus subtilis 0.333 0.333 1 PMID:11471740 -2.7.2.4 atp arabidopsis thaliana 23.4 14.5 4 PMID:17140415 -2.7.2.4 atp bacillus subtilis 15.87 15.25 3 PMID:15033471 -2.7.2.4 atp saccharomyces cerevisiae 49.3 49.3 1 PMID:14623312 -2.7.2.4 atp thermus thermophilus 15.25 13.559999999999999 2 PMID:15033471 -2.7.2.4 l-aspartate escherichia coli 56.7 14.2 5 PMID:11888289 -2.7.2.4 l-aspartate methanocaldococcus jannaschii 245.0 128.5 2 PMID:17012784 -2.7.2.4 l-aspartate saccharomyces cerevisiae 227.0 136.8 2 PMID:14623312;PMID:15358146 -2.7.2.4 l-aspartate streptomyces murayamaensis 17.4 17.4 1 PMID:27485103 -2.7.2.4 l-aspartate thermus thermophilus 25.0 25.0 1 PMID:16232547 -2.7.2.7 2-ethylbutyrate listeria monocytogenes 0.11 0.11 1 PMID:27940001 -2.7.2.7 2-methylbutyrate listeria monocytogenes 0.27 0.27 1 PMID:27940001 -2.7.2.7 2-methylbutyrate nitratidesulfovibrio vulgaris 1.59 1.59 1 PMID:32166312 -2.7.2.7 2-methylpentanoate listeria monocytogenes 0.31 0.31 1 PMID:27940001 -2.7.2.7 3-methylpentanoate listeria monocytogenes 0.35 0.35 1 PMID:27940001 -2.7.2.7 atp nitratidesulfovibrio vulgaris 7.03 7.03 1 PMID:32166312 -2.7.2.7 butanoate listeria monocytogenes 0.84 0.84 1 PMID:27940001 -2.7.2.7 butanoate nitratidesulfovibrio vulgaris 3.81 3.81 1 PMID:32166312 -2.7.2.7 hexanoate listeria monocytogenes 21.85 21.85 1 PMID:27940001 -2.7.2.7 isobutyrate listeria monocytogenes 0.4 0.4 1 PMID:27940001 -2.7.2.7 isobutyrate nitratidesulfovibrio vulgaris 2.94 2.94 1 PMID:32166312 -2.7.2.7 isovalerate listeria monocytogenes 0.42 0.42 1 PMID:27940001 -2.7.2.7 isovalerate nitratidesulfovibrio vulgaris 2.18 2.18 1 PMID:32166312 -2.7.2.7 pentanoate listeria monocytogenes 1.2 1.2 1 PMID:27940001 -2.7.2.7 propionate listeria monocytogenes 2.59 2.59 1 PMID:27940001 -2.7.2.7 propionate nitratidesulfovibrio vulgaris 4.35 4.35 1 PMID:32166312 -2.7.2.7 valerate nitratidesulfovibrio vulgaris 7.33 7.33 1 PMID:32166312 -2.7.2.8 atp saccharomyces cerevisiae 7.7 7.7 1 PMID:22529931 -2.7.2.8 n-acetyl-l-glutamate arabidopsis thaliana 187.5 126.1 3 PMID:19409905 -2.7.2.8 n-acetyl-l-glutamate corynebacterium glutamicum 45.1 38.25 4 PMID:21901472;PMID:22101454 -2.7.2.8 n-acetyl-l-glutamate saccharomyces cerevisiae 4.9 4.9 1 PMID:22529931 -2.7.2.8 n-acetyl-l-glutamate synechococcus elongatus 40.4 26.75 2 PMID:19409905 -2.7.3.1 glycocyamine namalycastis sp. 25.3 24.65 2 PMID:15694586 -2.7.3.13 atp campylobacter jejuni 2.5 2.5 1 PMID:28650156 -2.7.3.13 d-glutamine campylobacter jejuni 1.5 1.5 1 PMID:30142271 -2.7.3.13 gamma-l-glutamyl hydrazide campylobacter jejuni 0.41 0.41 1 PMID:30142271 -2.7.3.13 gamma-l-glutamyl hydroxamate campylobacter jejuni 2.1 2.1 1 PMID:30142271 -2.7.3.13 l-glutamine campylobacter jejuni 2.5 2.5 1 PMID:30142271 -2.7.3.2 adp homo sapiens 483.3 220.0 4 PMID:15804623 -2.7.3.2 adp oryctolagus cuniculus 370.0 370.0 1 PMID:18433830 -2.7.3.2 alpha-(rp)-borano substituted adp oryctolagus cuniculus 0.06 0.06 1 PMID:18433830 -2.7.3.2 alpha-(sp)-borano substituted adp oryctolagus cuniculus 0.03 0.03 1 PMID:18433830 -2.7.3.2 atp homo sapiens 215.0 129.0 10 PMID:15804623;PMID:16801217;PMID:28916380 -2.7.3.2 atp oryctolagus cuniculus 148.0 2.16 8 PMID:16005271 -2.7.3.2 atp physeter macrocephalus 38.4 37.4 2 PMID:17805948 -2.7.3.2 creatine cryptosporidium muris 30.0 30.0 2 PMID:32470517 -2.7.3.2 creatine danio rerio 159.0 20.1 4 PMID:16451808;PMID:20558199 -2.7.3.2 creatine dendronephthya gigantea 41.3 41.3 1 PMID:16451808 -2.7.3.2 creatine hediste diversicolor 27.9 21.45 2 PMID:16451808 -2.7.3.2 creatine homo sapiens 417.0 170.0 11 PMID:15504039;PMID:15804623;PMID:20381520;PMID:20558199;PMID:28916380 -2.7.3.2 creatine lethenteron camtschaticum 25.2 18.85 2 PMID:16451808 -2.7.3.2 creatine mus musculus 16.3 13.1 3 PMID:16451808 -2.7.3.2 creatine oryctolagus cuniculus 148.0 148.0 1 PMID:16005271 -2.7.3.2 creatine physeter macrocephalus 38.4 37.4 2 PMID:17805948 -2.7.3.2 cyclocreatine homo sapiens 35.2 35.2 1 PMID:15504039 -2.7.3.2 glycocyamine cryptosporidium muris 0.5 0.5 1 PMID:32470517 -2.7.3.2 n-ethylglycocyamine homo sapiens 14.5 14.5 1 PMID:15504039 -2.7.3.2 phosphocreatine homo sapiens 483.3 220.0 4 PMID:15804623 -2.7.3.3 adp desulfotalea psychrophila 1.11 1.11 1 PMID:18499493 -2.7.3.3 adp limulus polyphemus 140.0 140.0 1 PMID:12732621 -2.7.3.3 atp abyssogena kaikoi 22.9 22.9 1 PMID:18639645 -2.7.3.3 atp anthopleura japonica 129.0 129.0 1 PMID:17950825 -2.7.3.3 atp apostichopus japonicus 25.7 25.7 1 PMID:15115182 -2.7.3.3 atp caenorhabditis elegans 180.0 42.5 4 PMID:25981702 -2.7.3.3 atp cissites cephalotes 2.02 2.02 1 PMID:17368197 -2.7.3.3 atp corbicula japonica 73.3 59.0 2 PMID:12505165 -2.7.3.3 atp crassostrea sp. 47.5 47.5 1 PMID:15757662 -2.7.3.3 atp daphnia magna 18.6 18.6 1 PMID:32863281 -2.7.3.3 atp locusta migratoria manilensis 163.0 161.2 4 PMID:18070665;PMID:24157705 -2.7.3.3 atp myzostoma cirriferum 38.9 38.9 1 PMID:27095694 -2.7.3.3 atp sabellastarte spectabilis 39.5 38.05 2 * -2.7.3.3 atp sulfurovum lithotrophicum 88.0 88.0 1 PMID:23523720 -2.7.3.3 atp tetrahymena pyriformis 104.0 83.7 2 PMID:24726623 -2.7.3.3 atp toxocara canis 29.18 29.18 1 PMID:17574244 -2.7.3.3 d-arg sabellastarte spectabilis 40.8 22.25 2 PMID:17294143 -2.7.3.3 l-(+)-(s)-canavanine manduca sexta 27.3 27.3 1 PMID:193843 -2.7.3.3 l-arg abyssogena kaikoi 13.7 5.85 4 PMID:22016076 -2.7.3.3 l-arg anthopleura japonica 678.0 143.0 4 PMID:17950825;PMID:20434482 -2.7.3.3 l-arg apostichopus japonicus 29.93 22.18 4 PMID:16574215;PMID:21549684 -2.7.3.3 l-arg ascaris suum 45.9 45.9 1 PMID:21781373 -2.7.3.3 l-arg cissites cephalotes 2.02 2.02 2 PMID:17368197 -2.7.3.3 l-arg corbicula japonica 73.3 59.0 2 PMID:12505165 -2.7.3.3 l-arg locusta migratoria manilensis 163.0 161.2 4 PMID:22643639;PMID:23000252 -2.7.3.3 l-arg manduca sexta 139.0 139.0 1 PMID:193843 -2.7.3.3 l-arg sabellastarte spectabilis 46.0 20.599999999999998 4 PMID:17294143 -2.7.3.3 l-arg toxocara canis 81.0 55.09 2 PMID:17574244 -2.7.3.3 l-arginine abyssogena kaikoi 212.9 212.9 1 PMID:18639645 -2.7.3.3 l-arginine apostichopus japonicus 25.7 25.7 1 PMID:15115182 -2.7.3.3 l-arginine caenorhabditis elegans 180.0 42.5 4 PMID:25981702 -2.7.3.3 l-arginine crassostrea sp. 47.5 47.5 1 PMID:15757662 -2.7.3.3 l-arginine daphnia magna 18.6 18.6 1 PMID:32863281 -2.7.3.3 l-arginine euphausia superba 84.8 84.8 1 PMID:24690537 -2.7.3.3 l-arginine frankliniella occidentalis 6.74 6.74 1 PMID:30641133 -2.7.3.3 l-arginine locusta migratoria manilensis 163.0 161.2 2 PMID:24157705 -2.7.3.3 l-arginine myzostoma cirriferum 38.9 38.9 1 PMID:27095694 -2.7.3.3 l-arginine neocaridina denticulata 459.0 196.0 11 PMID:24727438 -2.7.3.3 l-arginine polybetes pythagoricus 75.0 75.0 1 PMID:28924503 -2.7.3.3 l-arginine sulfurovum lithotrophicum 88.0 88.0 1 PMID:23523720 -2.7.3.3 l-arginine tetrahymena pyriformis 104.0 83.7 2 PMID:24726623 -2.7.3.3 l-arginine tribolium castaneum 172.7 92.69999999999999 2 PMID:33127981 -2.7.3.3 l-phosphocanavanine manduca sexta 50.7 50.7 1 PMID:193843 -2.7.3.3 n5-(n-phosphonocarbamimidoyl)-l-ornithine limulus polyphemus 140.0 140.0 1 PMID:12732621 -2.7.3.3 nomega-phospho-l-arg manduca sexta 431.0 431.0 1 PMID:193843 -2.7.3.3 nomega-phospho-l-arg myxococcus xanthus 0.093 0.093 1 PMID:22389486 -2.7.3.3 nomega-phospho-l-arginine tribolium castaneum 146.1 84.05 2 PMID:33127981 -2.7.3.3 omega-n-phospho-l-arginine desulfotalea psychrophila 1.11 1.11 1 PMID:18499493 -2.7.3.4 atp clonorchis sinensis 22.59 17.78 3 PMID:24278491 -2.7.3.4 glycocyamine phytophthora sojae 1.4 1.4 1 PMID:23978736 -2.7.3.4 taurocyamine arenicola brasiliensis 14.3 11.865 2 PMID:16188310 -2.7.3.4 taurocyamine clonorchis sinensis 22.59 17.78 3 PMID:24278491 -2.7.3.4 taurocyamine phytophthora sojae 94.1 94.1 1 PMID:23978736 -2.7.3.4 taurocyamine riftia pachyptila 12.5 12.5 1 PMID:16188310 -2.7.4.1 (phosphate)45 mycobacterium tuberculosis 50.0 25.01 2 PMID:21381755 -2.7.4.1 (phosphate)65 mycobacterium tuberculosis 53.0 26.51 2 PMID:21381755 -2.7.4.1 (phosphate)n+1 cytophaga hutchinsonii 29.63 29.63 1 * -2.7.4.1 (phosphate)n+1 deinococcus radiodurans 132.0 132.0 1 * -2.7.4.1 (phosphate)n+1 paenarthrobacter aurescens 5.53 5.53 1 * -2.7.4.1 adp corynebacterium glutamicum 9.1 9.1 1 PMID:28417169 -2.7.4.1 adp cytophaga hutchinsonii 9.39 9.39 1 * -2.7.4.1 adp deinococcus radiodurans 0.4 0.4 1 * -2.7.4.1 adp escherichia coli 10.5 10.5 1 PMID:9012801 -2.7.4.1 adp francisella tularensis subsp. tularensis 317.0 3.17 3 PMID:26582818;PMID:29531036 -2.7.4.1 adp meiothermus ruber 0.246 0.246 1 PMID:29531036 -2.7.4.1 adp mycobacterium tuberculosis 943.0 210.0 3 PMID:21381755;PMID:22110640 -2.7.4.1 adp myxococcus xanthus 0.58 0.58 1 PMID:29127456 -2.7.4.1 adp paenarthrobacter aurescens 4.12 4.12 1 * -2.7.4.1 adp ruegeria pomeroyi 5.22 5.22 1 PMID:24930102 -2.7.4.1 amp cytophaga hutchinsonii 16.83 16.83 1 * -2.7.4.1 amp deinococcus radiodurans 94.47 94.47 1 * -2.7.4.1 amp delftia tsuruhatensis 56.0 56.0 1 PMID:31206993 -2.7.4.1 amp meiothermus ruber 7.1 7.1 1 PMID:29531036 -2.7.4.1 amp paenarthrobacter aurescens 21.24 21.24 1 * -2.7.4.1 atp corynebacterium glutamicum 74.0 74.0 1 PMID:17545325 -2.7.4.1 atp cytophaga hutchinsonii 0.29 0.29 1 * -2.7.4.1 atp escherichia coli 23.6 23.6 1 PMID:2164013 -2.7.4.1 atp francisella tularensis subsp. tularensis 1.46 1.46 1 PMID:26582818 -2.7.4.1 atp mycobacterium tuberculosis 46.9 23.474999999999998 2 PMID:21381755;PMID:22110640 -2.7.4.1 atp myxococcus xanthus 0.56 0.56 1 PMID:29127456 -2.7.4.1 atp paenarthrobacter aurescens 3.32 3.32 1 * -2.7.4.1 cdp escherichia coli 0.167 0.167 1 PMID:9012801 -2.7.4.1 dadp cytophaga hutchinsonii 0.58 0.58 1 * -2.7.4.1 dadp paenarthrobacter aurescens 0.55 0.55 1 * -2.7.4.1 damp cytophaga hutchinsonii 2.77 2.77 1 * -2.7.4.1 damp deinococcus radiodurans 0.06 0.06 1 * -2.7.4.1 damp paenarthrobacter aurescens 0.6 0.6 1 * -2.7.4.1 gdp cytophaga hutchinsonii 3.86 3.86 1 * -2.7.4.1 gdp escherichia coli 0.482 0.28515 2 PMID:10660553;PMID:9012801 -2.7.4.1 gdp francisella tularensis subsp. tularensis 3.69 3.69 1 PMID:26582818 -2.7.4.1 gdp mycobacterium tuberculosis 645.0 645.0 1 PMID:22110640 -2.7.4.1 gdp paenarthrobacter aurescens 2.12 2.12 1 * -2.7.4.1 gdp ruegeria pomeroyi 4.18 4.18 1 PMID:24930102 -2.7.4.1 gmp cytophaga hutchinsonii 6.91 6.91 1 * -2.7.4.1 gmp deinococcus radiodurans 0.8 0.8 1 * -2.7.4.1 gmp paenarthrobacter aurescens 0.97 0.97 1 * -2.7.4.1 gtp corynebacterium glutamicum 34.0 34.0 1 PMID:17545325 -2.7.4.1 gtp francisella tularensis subsp. tularensis 2.77 2.77 1 PMID:26582818 -2.7.4.1 gtp mycobacterium tuberculosis 0.08 0.08 1 PMID:21381755 -2.7.4.1 itp corynebacterium glutamicum 43.0 43.0 1 PMID:17545325 -2.7.4.1 phosphate neisseria meningitidis 47.0 47.0 1 PMID:8395468 -2.7.4.1 polyphosphate corynebacterium glutamicum 77.0 77.0 1 PMID:17545325 -2.7.4.1 polyphosphate escherichia coli 1.04 1.04 1 PMID:10660553 -2.7.4.1 polyphosphate(4) corynebacterium glutamicum 5.6 5.6 1 PMID:28417169 -2.7.4.1 polyphosphate25 pseudomonas aeruginosa 4.28 2.295 2 PMID:26576296 -2.7.4.1 polyphosphate65 pseudomonas aeruginosa 3.93 2.11 2 PMID:26576296 -2.7.4.1 udp escherichia coli 0.117 0.117 1 PMID:9012801 -2.7.4.1 udp ruegeria pomeroyi 4.9 4.9 1 PMID:24930102 -2.7.4.14 5-aza-cidofovir homo sapiens 0.47 0.47 1 PMID:26824416 -2.7.4.14 ara-cmp homo sapiens 150.0 97.5 2 PMID:12694191 -2.7.4.14 beta-l-2',3'-dideoxy-3'-thiacytidine monophosphate dictyostelium sp. 10.0 10.0 1 PMID:12694191 -2.7.4.14 beta-l-2',3'-dideoxy-3'-thiacytidine monophosphate homo sapiens 36.0 25.0 2 PMID:12694191 -2.7.4.14 cidofovir homo sapiens 0.09 0.09 1 PMID:26824416 -2.7.4.14 cmp arabidopsis thaliana 8.57 8.57 1 PMID:9576794 -2.7.4.14 cmp dictyostelium sp. 410.0 410.0 1 PMID:12694191 -2.7.4.14 cmp homo sapiens 130.0 125.0 3 PMID:12694191;PMID:26824416 -2.7.4.14 cytarabine homo sapiens 130.0 130.0 1 PMID:26824416 -2.7.4.14 dcmp dictyostelium sp. 22.0 22.0 1 PMID:12694191 -2.7.4.14 dcmp homo sapiens 73.0 30.0 3 PMID:12694191;PMID:26824416 -2.7.4.14 dump homo sapiens 5.8 5.8 1 PMID:26824416 -2.7.4.14 ump arabidopsis thaliana 7.64 7.64 1 PMID:9576794 -2.7.4.14 ump dictyostelium sp. 217.0 217.0 1 PMID:12694191 -2.7.4.14 ump homo sapiens 188.0 130.0 3 PMID:12694191;PMID:26824416 -2.7.4.14 ump sus scrofa 174.0 13.7 3 PMID:9685727 -2.7.4.16 thiamine phosphate pyrobaculum calidifontis 0.063 0.063 1 PMID:26639844 -2.7.4.2 adp streptococcus pneumoniae 3.9 3.9 1 PMID:12424232 -2.7.4.2 adpbetas streptococcus pneumoniae 0.095 0.095 1 PMID:12424232 -2.7.4.2 atp streptococcus pneumoniae 3.4 3.4 1 PMID:12424232 -2.7.4.2 phosphomevalonate sus scrofa 10.2 10.2 1 PMID:6248101 -2.7.4.21 1d-myo-inositol hexakisphosphate homo sapiens 0.03 0.03 1 PMID:23240582 -2.7.4.22 atp helicobacter pylori 436.2 312.9 2 PMID:20602229 -2.7.4.22 atp streptococcus pneumoniae 175.0 147.5 2 PMID:15324307 -2.7.4.22 ump helicobacter pylori 545.2 331.55 2 PMID:20602229 -2.7.4.22 ump saccharolobus solfataricus 19.0 19.0 1 PMID:17297917 -2.7.4.24 1,5-bis-diphospho-1d-myo-inositol 2,3,4,6-tetrakisphosphate homo sapiens 0.19 0.19 1 PMID:23240582 -2.7.4.24 1-diphospho-1d-myo-inositol 2,3,4,5,6-pentakisphosphate homo sapiens 0.002 0.002 1 PMID:23240582 -2.7.4.24 1d-myo-inositol 5-diphosphate pentakisphosphate homo sapiens 38.0 21.0 2 PMID:17690096 -2.7.4.24 5-diphospho-1d-myo-inositol 1,2,3,4,6-pentakisphosphate homo sapiens 0.13 0.13 1 PMID:23240582 -2.7.4.25 2',3'-dideoxy-cmp escherichia coli 0.047 0.047 1 PMID:11827479 -2.7.4.25 ara-cmp escherichia coli 56.0 56.0 1 PMID:11827479 -2.7.4.25 cmp escherichia coli 103.0 103.0 2 PMID:11827479;PMID:17542990 -2.7.4.25 cmp escherichia coli k-12 103.0 103.0 1 PMID:17542990 -2.7.4.25 cmp mycobacterium tuberculosis 52.0 52.0 1 PMID:19181797 -2.7.4.25 dcmp escherichia coli 109.0 108.5 2 PMID:11827479;PMID:17542990 -2.7.4.25 dcmp escherichia coli k-12 108.0 108.0 1 PMID:17542990 -2.7.4.25 dcmp mycobacterium tuberculosis 30.0 30.0 1 PMID:19181797 -2.7.4.25 ump escherichia coli 0.82 0.82 1 PMID:17542990 -2.7.4.25 ump escherichia coli k-12 0.82 0.82 1 PMID:17542990 -2.7.4.25 ump mycobacterium tuberculosis 12.2 12.2 1 PMID:19181797 -2.7.4.26 (2e)-hex-2-en-1-yl phosphate thermoplasma acidophilum 18.0 18.0 1 PMID:30998839 -2.7.4.26 (2z)-hex-2-en-1-yl phosphate thermoplasma acidophilum 112.0 112.0 1 PMID:30998839 -2.7.4.26 2-methylprop-2-en-1-yl phosphate thermoplasma acidophilum 12.0 12.0 1 PMID:30998839 -2.7.4.26 3-bromobut-3-en-1-yl phosphate thermoplasma acidophilum 226.0 226.0 1 PMID:30998839 -2.7.4.26 atp haloferax volcanii 16.3 16.3 1 PMID:24375100 -2.7.4.26 but-3-en-1-yl phosphate methanothermobacter thermautotrophicus 20.5 20.5 1 PMID:19928876 -2.7.4.26 but-3-en-1-yl phosphate thermoplasma acidophilum 187.0 97.535 2 PMID:19928876;PMID:30998839 -2.7.4.26 but-3-yn-1-yl phosphate thermoplasma acidophilum 34.0 34.0 1 PMID:30998839 -2.7.4.26 butyl phosphate methanothermobacter thermautotrophicus 31.8 31.8 1 PMID:19928876 -2.7.4.26 butyl phosphate thermoplasma acidophilum 9.9 9.9 1 PMID:19928876 -2.7.4.26 dimethylallyl phosphate arabidopsis thaliana 2.7 2.7 1 PMID:26216978 -2.7.4.26 dimethylallyl phosphate methanothermobacter thermautotrophicus 34.0 34.0 1 PMID:19928876 -2.7.4.26 dimethylallyl phosphate thermoplasma acidophilum 32.0 21.65 2 PMID:19928876;PMID:30998839 -2.7.4.26 fosfomycin thermoplasma acidophilum 0.04 0.04 1 PMID:22148590 -2.7.4.26 geranyl phosphate arabidopsis thaliana 0.0039 0.0039 1 PMID:26216978 -2.7.4.26 geranyl phosphate methanothermobacter thermautotrophicus 0.0142 0.0142 1 PMID:19928876 -2.7.4.26 geranyl phosphate thermoplasma acidophilum 0.047 0.047 1 PMID:19928876 -2.7.4.26 isopentenyl diphosphate methanothermobacter thermautotrophicus 4.5 4.5 1 PMID:19928876 -2.7.4.26 isopentenyl diphosphate thermoplasma acidophilum 2.75 2.75 1 PMID:19928876 -2.7.4.26 isopentenyl phosphate arabidopsis thaliana 3.7 3.7 1 PMID:26216978 -2.7.4.26 isopentenyl phosphate haloferax volcanii 16.3 16.3 1 PMID:24375100 -2.7.4.26 isopentenyl phosphate methanocaldococcus jannaschii 330.0 165.73 2 PMID:16621811;PMID:20392112 -2.7.4.26 isopentenyl phosphate methanothermobacter thermautotrophicus 27.5 27.5 1 PMID:19928876 -2.7.4.26 isopentenyl phosphate thermoplasma acidophilum 44.0 8.0 3 PMID:19928876;PMID:22148590;PMID:30998839 -2.7.4.26 isopentenyl thiolophosphate methanothermobacter thermautotrophicus 8.22 8.22 1 PMID:19928876 -2.7.4.26 isopentenyl thiolophosphate thermoplasma acidophilum 2.84 2.84 1 PMID:19928876 -2.7.4.26 pent-4-en-1-yl phosphate thermoplasma acidophilum 92.0 92.0 1 PMID:30998839 -2.7.4.26 pent-4-yn-1-yl phosphate thermoplasma acidophilum 44.0 44.0 1 PMID:30998839 -2.7.4.3 adp homo sapiens 783.0 783.0 1 PMID:5062950 -2.7.4.3 amp bacillus subtilis 0.135 0.073 5 PMID:18093993 -2.7.4.3 amp homo sapiens 842.3 842.15 2 PMID:17662886 -2.7.4.3 amp schistosoma mansoni 50.0 29.15 2 PMID:22841753 -2.7.4.3 atp homo sapiens 879.5 683.0 5 PMID:17662886;PMID:1969292;PMID:22038794;PMID:5062950 -2.7.4.3 atp oryctolagus cuniculus 417.0 417.0 1 * -2.7.4.3 atp plasmodium falciparum 5.4 5.4 1 PMID:18973776 -2.7.4.3 atp schistosoma mansoni 25.0 15.0 2 PMID:22841753 -2.7.4.3 atp sulfolobus acidocaldarius 170.0 170.0 1 PMID:8922285 -2.7.4.3 atp vibrio natriegens 325.0 325.0 1 * -2.7.4.33 (phosphate)3 pseudomonas aeruginosa 3.4 2.65 2 PMID:19001261 -2.7.4.33 (phosphate)n pseudomonas aeruginosa 37.7 22.200000000000003 2 PMID:19001261 -2.7.4.33 amp acinetobacter johnsonii 166.7 159.2 2 PMID:15716459 -2.7.4.33 amp pseudomonas aeruginosa 44.6 44.6 1 PMID:19001261 -2.7.4.33 gmp acinetobacter johnsonii 35.0 35.0 1 PMID:15716459 -2.7.4.33 gmp pseudomonas aeruginosa 13.4 13.4 1 PMID:19001261 -2.7.4.34 gdp francisella tularensis subsp. tularensis 3.69 3.69 1 PMID:26582818 -2.7.4.34 gmp delftia tsuruhatensis 2.5 2.5 1 PMID:31206993 -2.7.4.34 gtp francisella tularensis subsp. tularensis 2.77 2.77 1 PMID:26582818 -2.7.4.4 [2-[(2r,3s,5r)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)tetrahydrofuran-2-yl]ethyl]boronic acid homo sapiens 0.014 0.014 1 PMID:22733592 -2.7.4.4 damp homo sapiens 500.0 290.0 2 PMID:21567966 -2.7.4.4 tmp homo sapiens 1.25 1.25 1 PMID:22733592 -2.7.4.6 8-bromoinosine 5'-diphosphate mycobacterium tuberculosis 0.159 0.159 1 PMID:23526954 -2.7.4.6 atp aspergillus fumigatus 321.0 321.0 1 PMID:33089641 -2.7.4.6 atp lathyrus oleraceus 2085.0 2085.0 1 * -2.7.4.6 atp mycobacterium tuberculosis 264.0 264.0 1 PMID:23526954 -2.7.4.6 ctp aspergillus fumigatus 53.1 53.1 1 PMID:33089641 -2.7.4.6 ctp oryza sativa 229.0 89.0 3 PMID:21897044 -2.7.4.6 dcdp lathyrus oleraceus 106.0 106.0 1 PMID:15466238 -2.7.4.6 dtdp lathyrus oleraceus 147.0 147.0 1 PMID:15466238 -2.7.4.6 dtdp saccharomyces cerevisiae 13.3 13.3 1 PMID:1659321 -2.7.4.6 dtdp white spot syndrome virus 0.89 0.89 1 PMID:26315341 -2.7.4.6 gdp thermus thermophilus 38.0 38.0 1 PMID:14501133 -2.7.4.6 gtp aspergillus fumigatus 188.0 188.0 1 PMID:33089641 -2.7.4.6 gtp oryza sativa 49.4 27.7 3 PMID:21897044 -2.7.4.6 itp aspergillus fumigatus 83.2 83.2 1 PMID:33089641 -2.7.4.6 ttp aspergillus fumigatus 178.0 178.0 1 PMID:33089641 -2.7.4.6 ttp oryza sativa 55.0 33.5 3 PMID:21897044 -2.7.4.6 utp aspergillus fumigatus 140.0 140.0 1 PMID:33089641 -2.7.4.7 2-methyl-4-amino-5-hydroxymethylpyrimidine escherichia coli 0.0867 0.0867 1 * -2.7.4.7 2-methyl-4-amino-5-hydroxymethylpyrimidine phosphate escherichia coli 0.07 0.07 1 * -2.7.4.7 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine escherichia coli 0.034 0.034 1 PMID:28729425 -2.7.4.7 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine sulfurimonas denitrificans 0.011 0.011 1 PMID:28729425 -2.7.4.7 atp escherichia coli 0.07 0.07 1 * -2.7.4.8 atp saccharomyces cerevisiae 90.0 90.0 1 PMID:8910414 -2.7.4.8 dgmp brugia malayi 510.0 510.0 1 PMID:25061727 -2.7.4.8 dgmp plasmodium falciparum 43.0 43.0 1 PMID:18374996 -2.7.4.8 dgmp saccharomyces cerevisiae 51.0 51.0 1 PMID:8910414 -2.7.4.8 gmp bacillus subtilis 52.0 52.0 1 PMID:24722991 -2.7.4.8 gmp brugia malayi 1500.0 1500.0 1 PMID:25061727 -2.7.4.8 gmp escherichia coli 209.0 209.0 1 PMID:24722991 -2.7.4.8 gmp homo sapiens 58.5 58.5 1 PMID:31201273 -2.7.4.8 gmp oryza sativa japonica group 70.0 46.5 2 PMID:24722991 -2.7.4.8 gmp plasmodium falciparum 946.0 946.0 1 PMID:18374996 -2.7.4.8 gmp saccharomyces cerevisiae 394.0 394.0 1 PMID:8910414 -2.7.4.8 gtp bos taurus 130.0 130.0 1 PMID:3024975 -2.7.4.9 (e)-5-(2-bromovinyl)-deoxyuridine monophosphate orthopoxvirus vaccinia 0.86 0.86 1 PMID:18971333 -2.7.4.9 2',3'-didehydro-2',3'-dideoxythymidine 5'-monophosphate homo sapiens 0.09 0.09 1 PMID:12614151 -2.7.4.9 3'-amino-3'-deoxythymidine 5'-monophosphate homo sapiens 0.14 0.14 1 PMID:12614151 -2.7.4.9 3'-azido-3'-deoxythymidine 5'-monophosphate homo sapiens 0.012 0.01 3 PMID:12614151;PMID:18559937 -2.7.4.9 3'-azido-3'-deoxythymidine monophosphate candida albicans 0.5 0.4 2 PMID:28742342 -2.7.4.9 3'-azido-3'-deoxythymidine monophosphate homo sapiens 0.012 0.012 1 PMID:32064397 -2.7.4.9 3'-fluoro-3'-deoxythymidine 5'-monophosphate homo sapiens 0.03 0.03 1 PMID:12614151 -2.7.4.9 5-bromo-dump homo sapiens 1.2 1.2 1 PMID:21128666 -2.7.4.9 atp plasmodium falciparum 3.3 3.3 1 PMID:31934749 -2.7.4.9 atp streptococcus pneumoniae 8.9 8.9 1 PMID:11964185 -2.7.4.9 atp white spot syndrome virus 3.16 3.16 1 PMID:26315341 -2.7.4.9 atp wolbachia endosymbiont of brugia malayi 38.1 38.1 1 PMID:24556140 -2.7.4.9 ddtmp homo sapiens 0.03 0.03 1 PMID:12614151 -2.7.4.9 dgmp candida albicans 0.008 0.007 2 PMID:28742342 -2.7.4.9 dgmp plasmodium falciparum 2.9 2.65 2 PMID:18477629;PMID:31934749 -2.7.4.9 dimp plasmodium falciparum 0.44 0.44 1 PMID:18477629 -2.7.4.9 dtmp homo sapiens 3.0 0.76 3 PMID:18559937;PMID:21128666 -2.7.4.9 dtmp plasmodium falciparum 3.4 3.4 1 PMID:18477629 -2.7.4.9 dtmp streptococcus pneumoniae 8.9 8.9 1 PMID:11964185 -2.7.4.9 dtmp white spot syndrome virus 3.56 3.56 1 PMID:26315341 -2.7.4.9 dump homo sapiens 4.8 4.8 1 PMID:21128666 -2.7.4.9 dump plasmodium falciparum 4.1 4.1 1 PMID:18477629 -2.7.4.9 n1-[(e)-3-dihydroxyphosphonyl-prop-2-enyl]-thymine homo sapiens 0.6 0.6 1 PMID:21128666 -2.7.4.9 n1-[(e)-4-dihydroxyphosphonyl-but-2-enyl]-5-chlorouracil homo sapiens 0.9 0.7 2 PMID:21128666 -2.7.4.9 n1-[(e)-4-dihydroxyphosphonyl-but-2-enyl]-5-fluorouracil homo sapiens 0.73 0.73 1 PMID:21128666 -2.7.4.9 n1-[(e)-4-dihydroxyphosphonyl-but-2-enyl]-thymine homo sapiens 0.84 0.84 1 PMID:21128666 -2.7.4.9 n1-[(e)-4-dihydroxyphosphonyl-but-2-enyl]-uracil homo sapiens 0.48 0.48 1 PMID:21128666 -2.7.4.9 n1-[(e)-5-dihydroxyphosphonyl-pent-2-enyl]-5-bromouracil homo sapiens 0.058 0.058 1 PMID:21128666 -2.7.4.9 n1-[(e)-5-dihydroxyphosphonyl-pent-2-enyl]-5-chlorouracil homo sapiens 0.1 0.1 1 PMID:21128666 -2.7.4.9 n1-[(e)-5-dihydroxyphosphonyl-pent-2-enyl]-5-fluorouracil homo sapiens 0.09 0.09 1 PMID:21128666 -2.7.4.9 n1-[(e)-5-dihydroxyphosphonyl-pent-2-enyl]-thymine homo sapiens 0.32 0.32 1 PMID:21128666 -2.7.4.9 n1-[(e)-5-dihydroxyphosphonyl-pent-2-enyl]-uracil homo sapiens 0.074 0.074 1 PMID:21128666 -2.7.4.9 tmp candida albicans 8.7 7.8 2 PMID:28742342 -2.7.4.9 tmp homo sapiens 0.73 0.565 2 PMID:12614151;PMID:32064397 -2.7.4.9 tmp plasmodium falciparum 3.4 3.25 2 PMID:19749371;PMID:31934749 -2.7.6.1 atp mycobacterium tuberculosis 0.66 0.66 1 PMID:22745722 -2.7.6.1 atp mycolicibacterium smegmatis 83.5 83.5 1 PMID:28419153 -2.7.6.1 atp thermus thermophilus 12.0 6.265 2 * -2.7.6.1 d-ribose 5-phosphate mycobacterium tuberculosis 60.68 40.85 4 PMID:21085589;PMID:22745722 -2.7.6.1 d-ribose 5-phosphate mycolicibacterium smegmatis 77.6 77.6 1 PMID:28419153 -2.7.6.1 d-ribose 5-phosphate pyrobaculum calidifontis 311.0 311.0 1 PMID:27517698 -2.7.6.1 d-ribose 5-phosphate thermus thermophilus 13.0 6.715 2 * -2.7.6.1 mg-atp2- mycobacterium tuberculosis 44.3 35.5 3 PMID:21085589 -2.7.6.1 mn-atp2- mycobacterium tuberculosis 46.3 45.7 2 PMID:21085589 -2.7.6.2 atp homo sapiens 0.069 0.069 1 PMID:12953792 -2.7.6.2 thiamine homo sapiens 0.069 0.069 1 PMID:12953792 -2.7.6.3 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine francisella tularensis 0.17 0.17 1 PMID:24975935 -2.7.6.5 gdp mycolicibacterium smegmatis 73.0 73.0 1 PMID:22636779 -2.7.6.5 gtp mycobacterium tuberculosis 8.4 0.47 9 PMID:16026164 -2.7.6.5 gtp mycolicibacterium smegmatis 127.0 127.0 1 PMID:22636779 -2.7.7.1 adp-ribose francisella tularensis 3.6 3.6 1 PMID:18275811 -2.7.7.1 atp giardia duodenalis 2.44 2.44 1 * -2.7.7.1 atp homo sapiens 53.9 8.8 10 PMID:17402747;PMID:31136762 -2.7.7.1 atp leishmania braziliensis 1.174 0.9764999999999999 4 PMID:26318236;PMID:32322725 -2.7.7.1 atp methanothermobacter thermautotrophicus 0.00278 0.000167 7 PMID:12810729 -2.7.7.1 atp mus musculus 15.0 2.33 3 PMID:23300904 -2.7.7.1 atp plasmodium falciparum 0.082 0.082 1 PMID:27984041 -2.7.7.1 diphosphate leishmania braziliensis 11.2 11.2 1 PMID:32322725 -2.7.7.1 nad+ leishmania braziliensis 16.6 16.6 1 PMID:32322725 -2.7.7.1 nicotinamide ribonucleotide escherichia coli 0.76 0.76 1 PMID:28455340 -2.7.7.1 nicotinamide ribonucleotide giardia duodenalis 3.04 3.04 1 * -2.7.7.1 nicotinamide ribonucleotide leishmania braziliensis 0.76 0.724 4 PMID:26318236;PMID:32322725 -2.7.7.1 nicotinamide ribonucleotide mus musculus 15.5 1.81 4 PMID:20943658;PMID:23300904 -2.7.7.1 nicotinamide ribonucleotide plasmodium falciparum 0.087 0.087 1 PMID:27984041 -2.7.7.1 nicotinamide ribonucleotide saccharomyces cerevisiae 35.33 35.33 1 PMID:24759102 -2.7.7.1 nicotinic acid mononucleotide homo sapiens 42.9 6.9 9 PMID:17402747 -2.7.7.1 nmn homo sapiens 53.8 8.8 9 PMID:17402747 -2.7.7.1 nmnh homo sapiens 18.6 7.2 9 PMID:17402747 -2.7.7.1 tiazofurin riboside 5'-monophosphate homo sapiens 14.9 0.55 9 PMID:17402747 -2.7.7.101 ntp saccharolobus solfataricus 0.00055 0.00055 1 PMID:20122937 -2.7.7.102 5'-cttcttctgtgc-3' saccharolobus islandicus 0.1 0.1 1 PMID:17709343 -2.7.7.102 atp saccharolobus islandicus 0.11 0.11 1 PMID:17709343 -2.7.7.102 datp saccharolobus islandicus 0.16 0.16 1 PMID:17709343 -2.7.7.102 ntp saccharolobus solfataricus 0.00013 0.00013 1 PMID:20122937 -2.7.7.103 ctp campylobacter jejuni subsp. jejuni serotype o:2 0.095 0.095 1 PMID:29023101 -2.7.7.103 n5-phospho-l-glutamine campylobacter jejuni subsp. jejuni serotype o:2 0.095 0.095 1 PMID:29023101 -2.7.7.107 (2-aminoethyl)phosphonate lancefieldella rimae 3.7 3.7 1 PMID:31420548 -2.7.7.107 (2-aminoethyl)phosphonate treponema denticola 1.05 1.05 1 PMID:31420548 -2.7.7.109 gtp methanocaldococcus jannaschii 0.023 0.023 1 PMID:24249552 -2.7.7.110 atp methanothermobacter marburgensis 0.12 0.12 1 PMID:25882909 -2.7.7.12 alpha-d-galactose 1-phosphate escherichia coli 780.0 281.0 5 PMID:10529216;PMID:10820011;PMID:12418221;PMID:5338129;PMID:7873670;PMID:9772178 -2.7.7.12 alpha-d-galactose 1-phosphate homo sapiens 98.0 9.3 3 PMID:10811638 -2.7.7.12 alpha-d-galactose 1-phosphate saccharomyces cerevisiae 987.0 987.0 1 PMID:387754;PMID:6292668 -2.7.7.12 alpha-d-glucose 1-phosphate homo sapiens 17.7 17.7 1 PMID:23583749 -2.7.7.12 udp-alpha-d-glucose homo sapiens 13.6 13.6 1 PMID:23583749 -2.7.7.12 udp-galactose escherichia coli 283.0 283.0 1 PMID:10529216;PMID:10820011 -2.7.7.13 alpha-d-mannose 1-phosphate helicobacter pylori 10.3 10.3 1 PMID:12023023 -2.7.7.13 gdp-alpha-d-mannose burkholderia cepacia 195.9 195.9 1 PMID:17184737 -2.7.7.13 gdpmannose helicobacter pylori 22.1 22.1 1 PMID:12023023 -2.7.7.14 ctp homo sapiens 0.25 0.25 1 PMID:24802409 -2.7.7.14 ctp trypanosoma brucei 1.15 1.15 1 PMID:19555461 -2.7.7.14 ethanolamine phosphate homo sapiens 0.25 0.25 1 PMID:24802409 -2.7.7.14 ethanolamine phosphate plasmodium falciparum 3.4 3.4 1 PMID:23198904 -2.7.7.15 ctp plasmodium falciparum 1.45 1.45 1 PMID:29895950 -2.7.7.15 ctp rattus norvegicus 33.3 33.3 1 PMID:3036843 -2.7.7.15 phosphocholine rattus norvegicus 17.7 2.22 3 PMID:10224101;PMID:9692923 -2.7.7.15 phosphocholine saccharomyces cerevisiae 31.3 16.405 2 PMID:11162399 -2.7.7.15 phosphocholine streptococcus pneumoniae 17.5 17.5 1 PMID:11786295 -2.7.7.18 atp plasmodium falciparum 0.082 0.082 1 PMID:27984041 -2.7.7.18 beta-nicotinate d-ribonucleotide escherichia coli 4.9 4.9 1 PMID:28455340 -2.7.7.18 nicotinate beta-d-ribonucleotide mycobacterium tuberculosis 5.5 5.5 1 PMID:25631047 -2.7.7.18 nicotinic acid ribonucleotide plasmodium falciparum 0.065 0.065 1 PMID:27984041 -2.7.7.19 (a)15 homo sapiens 0.18 0.18 1 PMID:21788334 -2.7.7.19 atp bos taurus 30.0 17.1015 2 PMID:15328606;PMID:237901 -2.7.7.19 atp homo sapiens 0.097 0.097 1 PMID:21788334 -2.7.7.19 ctp escherichia coli 0.43 0.43 1 PMID:15304219 -2.7.7.19 nucleotide zea mays 3.33 3.33 1 PMID:4946277 -2.7.7.19 rna(a)15 bos taurus 22.78 22.78 1 PMID:15328606 -2.7.7.2 atp arabidopsis thaliana 0.013 0.0119 4 PMID:18713732 -2.7.7.2 atp corynebacterium ammoniagenes 0.0917 0.0917 1 PMID:25801930 -2.7.7.2 atp homo sapiens 0.00691 0.00691 1 PMID:29316637 -2.7.7.2 atp nakaseomyces glabratus 0.087 0.087 1 PMID:19375431 -2.7.7.2 atp streptococcus pneumoniae 0.38 0.38 1 PMID:28790457 -2.7.7.2 fad corynebacterium ammoniagenes 7.5e-05 7.5e-05 1 PMID:9657684 -2.7.7.2 fmn arabidopsis thaliana 0.013 0.0119 4 PMID:18713732 -2.7.7.2 fmn corynebacterium ammoniagenes 2.17 0.0917 7 PMID:20471397;PMID:25801930;PMID:28341845;PMID:28779158;PMID:32466340;PMID:9657684 -2.7.7.2 fmn homo sapiens 0.08 0.0048 7 PMID:17049878;PMID:20060505;PMID:21924249;PMID:29316637 -2.7.7.2 fmn nakaseomyces glabratus 0.089 0.088 2 PMID:19375431;PMID:23663086 -2.7.7.2 fmn streptococcus pneumoniae 0.58 0.58 1 PMID:28790457 -2.7.7.2 roseoflavin mononucleotide homo sapiens 0.07 0.07 1 PMID:21924249 -2.7.7.23 diphosphate sulfurisphaera tokodaii 6.21 6.21 1 PMID:17307792 -2.7.7.23 n-acetyl-alpha-d-glucosamine 1-phosphate mycobacterium tuberculosis 100.0 100.0 1 PMID:29684272 -2.7.7.23 n-acetyl-alpha-d-glucosamine 1-phosphate sulfurisphaera tokodaii 9.97 6.255000000000001 2 PMID:17307792;PMID:27864169 -2.7.7.23 n-acetyl-alpha-d-glucosamine 1-phosphate yersinia pseudotuberculosis 0.95 0.95 1 PMID:25417006 -2.7.7.23 n-acetyl-d-glucosamine 1-phosphate escherichia coli 330.0 0.35 7 PMID:11084021 -2.7.7.23 n-acetyl-d-glucosamine 1-phosphate saccharomyces cerevisiae 15.4 15.4 1 PMID:9603950 -2.7.7.23 udp-n-acetyl-alpha-d-glucosamine sulfurisphaera tokodaii 8.4 8.4 1 PMID:17307792 -2.7.7.23 udp-n-acetyl-d-glucosamine escherichia coli 44.3 44.3 1 PMID:8689233 -2.7.7.23 utp mycobacterium tuberculosis 120.0 61.52 2 PMID:21594607;PMID:29684272 -2.7.7.23 utp sulfurisphaera tokodaii 3.53 3.53 1 PMID:17307792 -2.7.7.23 utp yersinia pseudotuberculosis 0.75 0.75 1 PMID:25417006 -2.7.7.24 2-deoxy-2-amino-alpha-d-glucose 1-phosphate streptococcus pneumoniae 4.5 2.3 2 PMID:25408103 -2.7.7.24 3-deoxy-3-amino-alpha-d-glucose 1-phosphate streptococcus pneumoniae 0.08 0.08 1 PMID:25408103 -2.7.7.24 3-deoxy-3-azido-alpha-d-glucose 1-phosphate streptococcus pneumoniae 0.0003 0.0003 1 PMID:25408103 -2.7.7.24 [[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl]methyl]phosphonic acid streptococcus pneumoniae 0.55 0.28 2 PMID:25408103 -2.7.7.24 alpha-d-glucose 1-phosphate caenorhabditis elegans 23.58 23.409999999999997 2 PMID:27009306 -2.7.7.24 alpha-d-glucose 1-phosphate mycobacterium tuberculosis 7.3 7.3 1 PMID:29076563 -2.7.7.24 alpha-d-glucose 1-phosphate pyrococcus horikoshii 6.18 6.18 1 PMID:29806742 -2.7.7.24 alpha-d-glucose 1-phosphate saccharothrix syringae 3.46 3.46 1 PMID:34819927 -2.7.7.24 alpha-d-glucose 1-phosphate streptococcus pneumoniae 24.0 12.008 2 PMID:25408103 -2.7.7.24 atp pyrococcus horikoshii 1.8 1.1 2 PMID:29806742 -2.7.7.24 atp salmonella enterica typhimurium 0.06 0.06 2 PMID:17434871 -2.7.7.24 ctp pyrococcus horikoshii 1.8 1.04 2 PMID:29806742 -2.7.7.24 ctp salmonella enterica typhimurium 0.1 0.099 2 PMID:17434871 -2.7.7.24 datp salmonella enterica typhimurium 1.88 1.88 2 PMID:17434871 -2.7.7.24 dctp salmonella enterica typhimurium 1.22 1.22 2 PMID:17434871 -2.7.7.24 dgtp salmonella enterica typhimurium 2.12 2.12 2 PMID:17434871 -2.7.7.24 dtdp-glucose sphingomonas elodea 1.35 0.9550000000000001 2 PMID:16085866 -2.7.7.24 dttp caenorhabditis elegans 28.2 28.2 1 PMID:27009306 -2.7.7.24 dttp mycobacterium tuberculosis 7.9 7.9 1 PMID:29076563 -2.7.7.24 dttp pyrococcus horikoshii 2.0 1.185 2 PMID:29806742 -2.7.7.24 dttp saccharothrix syringae 5.39 5.39 1 PMID:34819927 -2.7.7.24 dttp salmonella enterica typhimurium 30.83 22.915 2 PMID:17434871 -2.7.7.24 dttp streptomyces globisporus 2.9 2.9 1 PMID:14987060 -2.7.7.24 gtp pyrococcus horikoshii 2.5 1.43 2 PMID:29806742 -2.7.7.24 gtp salmonella enterica typhimurium 0.14 0.14 2 PMID:17434871 -2.7.7.24 utp caenorhabditis elegans 21.92 21.92 1 PMID:27009306 -2.7.7.24 utp pyrococcus horikoshii 12.1 7.1 2 PMID:29806742 -2.7.7.24 utp salmonella enterica 24.0 24.0 1 PMID:18387352 -2.7.7.24 utp salmonella enterica typhimurium 41.0 41.0 2 PMID:17434871 -2.7.7.27 adp-glucose solanum tuberosum 139.0 139.0 1 PMID:18199755 -2.7.7.27 alpha-d-glucose 1-phosphate solanum tuberosum 266.0 9.0 7 PMID:17137579;PMID:18199755;PMID:24018661 -2.7.7.27 alpha-d-glucose 1-phosphate zea mays 85.0 39.17 3 PMID:15951484;PMID:19625637 -2.7.7.27 atp escherichia coli 370.0 370.0 1 PMID:17079236 -2.7.7.27 atp solanum tuberosum 204.0 47.5 17 PMID:17137579;PMID:17207506;PMID:18199755;PMID:23603314;PMID:24018661 -2.7.7.27 atp zea mays 98.0 45.41 10 PMID:15951484;PMID:19889875;PMID:23603314;PMID:25600571 -2.7.7.27 diphosphate solanum tuberosum 121.0 121.0 1 PMID:18199755 -2.7.7.3 3'-dephospho-coa escherichia coli 0.000917 0.000917 1 PMID:10480925 -2.7.7.3 3'-dephospho-coa mycobacterium tuberculosis 4.808 4.808 1 PMID:20851704 -2.7.7.3 atp mycobacterium tuberculosis 4.547 4.547 1 PMID:20851704 -2.7.7.3 pantetheine 4'-phosphate mycobacterium tuberculosis 4.853 4.853 1 PMID:20851704 -2.7.7.30 2-amino-6-chloropurine-beta-d-riboside 5'-triphosphate homo sapiens 0.27 0.27 1 PMID:16086588 -2.7.7.30 2-aminoadenosine triphosphate homo sapiens 0.32 0.32 1 PMID:16086588 -2.7.7.30 7-deazaguanosine triphosphate homo sapiens 1.5 1.5 1 PMID:16086588 -2.7.7.30 8-oxoguanosine triphosphate homo sapiens 2.6 2.6 1 PMID:16086588 -2.7.7.30 atp homo sapiens 0.009 0.009 1 PMID:16086588 -2.7.7.30 atp vitis vinifera 0.22 0.22 1 PMID:22949207 -2.7.7.30 d-arabinose 1-phosphate homo sapiens 0.4 0.4 1 PMID:16086588 -2.7.7.30 fructose 1-phosphate homo sapiens 0.03 0.03 1 PMID:16086588 -2.7.7.30 galactose 1-phosphate homo sapiens 0.23 0.23 1 PMID:16086588 -2.7.7.30 glucosamine 1-phosphate homo sapiens 0.21 0.21 1 PMID:16086588 -2.7.7.30 glucose 1,6-diphosphate homo sapiens 0.18 0.18 1 PMID:16086588 -2.7.7.30 glucose 1-phosphate homo sapiens 0.32 0.32 1 PMID:16086588 -2.7.7.30 gtp homo sapiens 2.5 2.5 2 PMID:16086588;PMID:16185085 -2.7.7.30 gtp vitis vinifera 1.55 1.55 1 PMID:22949207 -2.7.7.30 itp homo sapiens 1.2 1.2 1 PMID:16086588 -2.7.7.30 l-fucose 1-phosphate homo sapiens 3.6 3.6 1 PMID:16086588 -2.7.7.30 mannose 1-phosphate homo sapiens 0.2 0.2 1 PMID:16086588 -2.7.7.30 n1-methylguanosine triphosphate homo sapiens 0.02 0.02 1 PMID:16086588 -2.7.7.30 n2-methylguanosine triphosphate homo sapiens 0.009 0.009 1 PMID:16086588 -2.7.7.30 o6-methylguanosine triphosphate homo sapiens 0.09 0.09 1 PMID:16086588 -2.7.7.30 tricyclic guanosine triphosphate homo sapiens 0.29 0.29 1 PMID:16086588 -2.7.7.30 xanthosine triphosphate homo sapiens 0.03 0.03 1 PMID:16086588 -2.7.7.31 2ba fam oligo bos taurus 0.893 0.893 1 PMID:32497424 -2.7.7.31 datp bos taurus 0.833 0.833 1 * -2.7.7.38 3-deoxy-d-manno-octulosonate aquifex aeolicus 9.5 9.5 1 PMID:21826242 -2.7.7.38 3-deoxy-d-manno-octulosonate burkholderia pseudomallei 0.088 0.088 1 PMID:32588669 -2.7.7.38 3-deoxy-d-manno-octulosonate burkholderia thailandensis 0.116 0.116 1 PMID:32588669 -2.7.7.38 3-deoxy-d-manno-octulosonate escherichia coli 21.9 12.5 3 PMID:21669179;PMID:29018092 -2.7.7.38 3-deoxy-d-manno-octulosonate pseudomonas aeruginosa 0.076 0.076 1 PMID:32588669 -2.7.7.38 8-azido-3,8-dideoxy-d-manno-oct-2-ulosonate escherichia coli 1.36 1.36 1 PMID:29018092 -2.7.7.38 ctp burkholderia pseudomallei 0.167 0.167 1 PMID:32588669 -2.7.7.38 ctp burkholderia thailandensis 0.142 0.142 1 PMID:32588669 -2.7.7.38 ctp pseudomonas aeruginosa 0.132 0.132 1 PMID:32588669 -2.7.7.39 cdpglycerol staphylococcus aureus 1.0 1.0 1 PMID:12637027 -2.7.7.39 ctp bacillus subtilis 18.8 18.8 1 PMID:9182537 -2.7.7.39 ctp staphylococcus aureus 2.6 2.6 1 PMID:12637027 -2.7.7.4 adenosine 5'-phosphosulfate brassica capitata 36.0 36.0 1 PMID:16662476 -2.7.7.4 adenylyl sulfate glycine max 24.5 24.5 1 PMID:16684499 -2.7.7.4 adenylyl sulfate thiobacillus denitrificans atcc 25259 260.0 260.0 1 PMID:19664586 -2.7.7.4 adenylylsulfate penicillium chrysogenum 46.6 46.6 1 PMID:14613928 -2.7.7.4 atp brassica capitata 36.0 19.565 2 PMID:16662476 -2.7.7.4 atp glycine max 1.49 1.49 1 PMID:16684499 -2.7.7.4 atp penicillium chrysogenum 24.4 17.6 2 PMID:14613928 -2.7.7.4 diphosphate brassica capitata 36.0 36.0 1 PMID:16662476 -2.7.7.4 diphosphate glycine max 19.1 19.1 1 PMID:16684499 -2.7.7.4 diphosphate penicillium chrysogenum 73.3 73.3 1 PMID:14613928 -2.7.7.4 moo42- penicillium chrysogenum 24.4 24.4 1 PMID:14613928 -2.7.7.4 so42- brassica capitata 3.13 3.13 1 PMID:16662476 -2.7.7.4 sulfate glycine max 2.11 2.11 1 PMID:16684499 -2.7.7.4 sulfate penicillium chrysogenum 10.8 10.8 1 PMID:14613928 -2.7.7.4 sulfate thiobacillus denitrificans atcc 25259 23.2 23.2 1 PMID:19664586 -2.7.7.40 ctp haemophilus influenzae 23.5 23.5 1 PMID:15362865 -2.7.7.40 ctp staphylococcus aureus 76.8 39.8 2 PMID:15362865 -2.7.7.40 d-ribitol 5-phosphate haemophilus influenzae 13.0 13.0 1 PMID:11305920 -2.7.7.41 1-stearoyl-2-arachidonoyl-sn-phosphatidic acid homo sapiens 8.0 5.45 4 PMID:25375833 -2.7.7.41 1-stearoyl-2-linoleoyl-sn-phosphatidic acid homo sapiens 3.2 3.05 4 PMID:25375833 -2.7.7.41 ctp saccharomyces cerevisiae 8.92 8.92 1 PMID:2822695 -2.7.7.41 phosphatidate saccharomyces cerevisiae 8.92 8.92 1 PMID:2822695 -2.7.7.43 8-o-methyl-n-acetylneuraminate neisseria meningitidis 21.0 21.0 1 PMID:21968653 -2.7.7.43 ctp [haemophilus] ducreyi 5.2 3.5 2 PMID:10320348;PMID:21968653 -2.7.7.43 ctp acetivibrio thermocellus 3.33 3.33 1 PMID:17602221 -2.7.7.43 ctp mus musculus 3.89 3.87 3 PMID:19666032 -2.7.7.43 ctp neisseria meningitidis 21.0 15.6 2 PMID:20491913;PMID:21968653 -2.7.7.43 ctp pasteurella multocida 4.6 4.6 1 PMID:21968653 -2.7.7.43 ctp streptococcus agalactiae 14.0 14.0 1 PMID:16369694 -2.7.7.43 ctp vibrio cholerae 3.97 3.97 1 PMID:31205019 -2.7.7.43 deaminoneuraminic acid streptococcus agalactiae 0.067 0.067 1 PMID:16369694 -2.7.7.43 n-acetylneuraminate [haemophilus] ducreyi 4.8 4.8 1 PMID:21968653 -2.7.7.43 n-acetylneuraminate neisseria meningitidis 32.0 25.5 2 PMID:21968653 -2.7.7.43 n-acetylneuraminate pasteurella multocida 4.2 4.2 1 PMID:21968653 -2.7.7.43 n-acylneuraminate acetivibrio thermocellus 2.25 2.25 1 PMID:17602221 -2.7.7.43 n-acylneuraminate vibrio cholerae 4.46 4.46 1 PMID:31205019 -2.7.7.43 n-glycolneuraminate vibrio cholerae 2.21 2.21 1 PMID:31205019 -2.7.7.43 n-glycolylneuraminate neisseria meningitidis 36.0 19.6 2 PMID:21968653 -2.7.7.43 n-glycolylneuraminic acid acetivibrio thermocellus 1.66 1.66 1 PMID:17602221 -2.7.7.43 n-glycolylneuraminic acid streptococcus agalactiae 0.68 0.68 1 PMID:16369694 -2.7.7.43 n-methylglycolylneuraminate neisseria meningitidis 2.9 2.9 1 PMID:21968653 -2.7.7.43 neu5ac streptococcus agalactiae 16.0 16.0 1 PMID:16369694 -2.7.7.43 neuac acetivibrio thermocellus 2.25 2.25 1 PMID:17602221 -2.7.7.43 neugc acetivibrio thermocellus 1.66 1.66 1 PMID:17602221 -2.7.7.43 sialic acid mus musculus 3.56 3.47 3 PMID:19666032 -2.7.7.45 gtp artemia sp. 1.6 1.4 2 PMID:7958281;PMID:8163476 -2.7.7.47 atp pseudomonas aeruginosa 0.61 0.61 1 PMID:29124199 -2.7.7.47 atp serratia marcescens 0.5 0.5 1 PMID:16819836 -2.7.7.47 spectinomycin pseudomonas aeruginosa 0.63 0.63 1 PMID:29124199 -2.7.7.47 spectinomycin serratia marcescens 0.5 0.5 1 PMID:16819836 -2.7.7.47 streptomycin pseudomonas aeruginosa 0.66 0.66 1 PMID:29124199 -2.7.7.47 streptomycin serratia marcescens 0.6 0.6 1 PMID:16819836 -2.7.7.48 atp hepacivirus hominis 0.000105 0.000105 1 PMID:10889032 -2.7.7.48 atp rhinovirus a16 0.000617 0.000617 1 PMID:12367717 -2.7.7.48 atp severe acute respiratory syndrome coronavirus 2 240.0 240.0 1 PMID:33283177 -2.7.7.48 ctp hepacivirus hominis 16.0 8.0000665 2 PMID:10889032;PMID:22303022 -2.7.7.48 ctp rhinovirus a16 0.000505 0.000505 1 PMID:12367717 -2.7.7.48 gtp dengue virus 0.345 0.345 1 PMID:25921066 -2.7.7.48 gtp hepacivirus hominis 0.005 0.0005 3 PMID:10675414;PMID:10889032;PMID:9882374 -2.7.7.48 gtp rhinovirus a16 0.0211 0.012425 2 PMID:12367717 -2.7.7.48 remdesivir triphosphate severe acute respiratory syndrome coronavirus 2 680.0 680.0 1 PMID:33283177 -2.7.7.48 utp hepacivirus hominis 0.0272 0.0027 4 PMID:10675414;PMID:10889032 -2.7.7.48 utp rhinovirus a16 0.23 0.11739000000000001 2 PMID:12367717 -2.7.7.48 utp severe acute respiratory syndrome coronavirus 2 308.0 308.0 1 PMID:33283177 -2.7.7.49 ((2r,3s,5r)-3-hydroxy-5-(6-(prop-2-yn-1-ylamino)-9h-purin-9-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate human immunodeficiency virus 1 0.047 0.03825 2 PMID:31201270 -2.7.7.49 ((2r,3s,5r)-5-(2-amino-6-(prop-2-yn-1-ylamino)-9h-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate human immunodeficiency virus 1 0.042 0.037000000000000005 2 PMID:31201270 -2.7.7.49 ((2r,3s,5r)-5-(2-amino-6-(prop-2-yn-1-yloxy)-9h-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate human immunodeficiency virus 1 0.0545 0.04125 2 PMID:31201270 -2.7.7.49 ((2r,3s,5r)-5-(6-amino-8-(prop-2-yn-1-ylamino)-9h-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate human immunodeficiency virus 1 0.0195 0.0195 1 PMID:31201270 -2.7.7.49 (-)-beta-2',3'-dideoxy-3'-thiacytidine triphosphat human immunodeficiency virus 1 0.15 0.15 1 PMID:17274599 -2.7.7.49 (-)-beta-2',3'-dideoxy-3'-thiacytidine triphosphate human immunodeficiency virus 1 0.15 0.15 1 PMID:17274599 -2.7.7.49 2',3'-dideoxy-ctp human immunodeficiency virus 1 0.67 0.67 1 PMID:17274599 -2.7.7.49 2'-deoxyadenosine 5'-triphosphate streptococcus agalactiae 0.0265 0.0265 1 PMID:18706966 -2.7.7.49 2'-deoxyguanosine 5'-triphosphate streptococcus agalactiae 1.33 1.33 1 PMID:18706966 -2.7.7.49 2'-deoxythymidine 5'-triphosphate streptococcus agalactiae 0.034 0.034 1 PMID:18706966 -2.7.7.49 3'-azido-2',3'-dideoxy-2,6-diaminopurine-beta-d-ribofuranosyl 5'-triphosphate human immunodeficiency virus 1 14.0 7.08 2 PMID:21914723 -2.7.7.49 3'-azido-2',3'-dideoxy-2-amino-6-chloropurine-beta-d-ribofuranosyl 5'-triphosphate human immunodeficiency virus 1 2.7 1.5350000000000001 2 PMID:21914723 -2.7.7.49 3'-azido-2',3'-dideoxy-2-amino-6-methoxypurine-beta-d-ribofuranosyl 5'-triphosphate human immunodeficiency virus 1 2.8 1.51 2 PMID:21914723 -2.7.7.49 3'-azido-2',3'-dideoxy-2-amino-6-n-allylaminopurine-beta-d-ribofuranosyl 5'-triphosphate human immunodeficiency virus 1 2.1 2.1 1 PMID:21914723 -2.7.7.49 3'-azido-2',3'-dideoxyadenosine triphosphate human immunodeficiency virus 1 14.0 14.0 1 PMID:21914723 -2.7.7.49 datp feline immunodeficiency virus 0.21 0.21 1 PMID:15823610 -2.7.7.49 datp feline leukemia virus 0.18 0.18 1 PMID:15823610 -2.7.7.49 datp human immunodeficiency virus 1 17.0 0.067 5 PMID:20924117;PMID:21914723;PMID:22595174;PMID:31201270 -2.7.7.49 dctp feline immunodeficiency virus 0.22 0.22 1 PMID:15823610 -2.7.7.49 dctp feline leukemia virus 0.15 0.15 1 PMID:15823610 -2.7.7.49 dctp human immunodeficiency virus 1 1.64 1.25 3 PMID:17274599;PMID:20924117 -2.7.7.49 deoxy-5'-ctp streptococcus agalactiae 0.0117 0.0117 1 PMID:18706966 -2.7.7.49 deoxynucleoside triphosphate prototype foamy virus 4.0 4.0 1 PMID:20113504 -2.7.7.49 deoxynucleoside triphosphate simian foamy virus 3.0 3.0 1 PMID:20113504 -2.7.7.49 dgtp feline immunodeficiency virus 0.51 0.51 1 PMID:15823610 -2.7.7.49 dgtp feline leukemia virus 0.56 0.56 1 PMID:15823610 -2.7.7.49 dgtp human immunodeficiency virus 1 17.3 8.65044 2 PMID:20924117;PMID:21914723 -2.7.7.49 dnan human immunodeficiency virus 1 1.1 0.7250000000000001 2 PMID:23149716 -2.7.7.49 dnan moloney murine leukemia virus 29.0 29.0 2 PMID:23026053;PMID:23149716 -2.7.7.49 dttp feline immunodeficiency virus 0.28 0.28 1 PMID:15823610 -2.7.7.49 dttp feline leukemia virus 0.17 0.17 1 PMID:15823610 -2.7.7.49 dttp human immunodeficiency virus 1 1.1 0.41 4 PMID:23149716;PMID:9325244 -2.7.7.49 dttp moloney murine leukemia virus 35.0 32.0 2 PMID:23026053;PMID:23149716 -2.7.7.49 dttp prototype foamy virus 5.5 5.5 1 PMID:20113504 -2.7.7.49 dttp simian foamy virus 7.1 7.1 1 PMID:20113504 -2.7.7.49 n-cyclobutyladenosine-phosphonyl diphosphate human immunodeficiency virus 1 0.07 0.07 1 PMID:22595174 -2.7.7.49 tenofovir diphosphate human immunodeficiency virus 1 0.15 0.15 1 PMID:22595174 -2.7.7.5 adenosine 5'-phosphosulfate arabidopsis thaliana 6.0 6.0 1 PMID:19896942 -2.7.7.5 adenosine 5'-phosphosulfate caenorhabditis elegans 2.6 2.6 1 PMID:19896942 -2.7.7.50 gtp orthopoxvirus vaccinia 0.0267 0.025 2 PMID:8662635 -2.7.7.50 rna orthopoxvirus vaccinia 0.0187 0.0167 2 PMID:8662635 -2.7.7.52 atp homo sapiens 2.93e-05 2.93e-05 1 PMID:27284165 -2.7.7.52 ctp homo sapiens 0.000914 0.000914 1 PMID:27284165 -2.7.7.52 gtp homo sapiens 0.000403 0.000403 1 PMID:27284165 -2.7.7.52 rnan trypanosoma brucei 0.0007 0.0005 2 PMID:20362585 -2.7.7.52 rnan containing a terminal u residue trypanosoma brucei 0.0033 0.0024000000000000002 2 PMID:20362585 -2.7.7.52 u6 snrnan homo sapiens 0.061 0.061 1 PMID:28589955 -2.7.7.52 utp homo sapiens 0.000248 0.000248 1 PMID:27284165 -2.7.7.52 utp trypanosoma brucei 0.003 0.00165 2 PMID:20417643 -2.7.7.53 adp saccharomyces cerevisiae 96.0 96.0 1 PMID:3009435 -2.7.7.53 p1,p4-bis(5'-adenosyl) tetraphosphate mycobacterium tuberculosis 8.48 8.48 1 PMID:21565198 -2.7.7.6 a10g2a2c2c escherichia phage t7 0.26 0.26 1 PMID:15196031 -2.7.7.6 a9g3a2c2c escherichia phage t7 4.0 4.0 1 PMID:15196031 -2.7.7.6 atp escherichia phage t7 0.482 0.482 1 PMID:12051935 -2.7.7.6 dgtp escherichia phage t7 0.22 0.22 1 PMID:9354643 -2.7.7.6 g2cac2c escherichia phage t7 0.03 0.03 1 PMID:15196031 -2.7.7.6 promoter complex escherichia phage t7 8.3 8.3 1 PMID:15196031 -2.7.7.6 rgtp escherichia phage t7 0.26 0.26 1 PMID:9354643 -2.7.7.6 t10g2t2c2c escherichia phage t7 0.23 0.23 1 PMID:15196031 -2.7.7.60 2-c-methyl-d-erythritol 4-phosphate bacillus subtilis 36.35 36.35 1 PMID:27821871 -2.7.7.60 2-c-methyl-d-erythritol 4-phosphate escherichia coli 48.4 43.425 2 PMID:15379557;PMID:27821871 -2.7.7.60 2-c-methyl-d-erythritol 4-phosphate francisella tularensis 1.0 1.0 1 PMID:21694781 -2.7.7.60 2-c-methyl-d-erythritol 4-phosphate plasmodium falciparum 7.6 7.6 1 PMID:29072835 -2.7.7.60 2-c-methyl-d-erythritol-4-phosphate escherichia coli 16.8 16.8 1 PMID:11408165 -2.7.7.60 2-c-methyl-d-erythritol-4-phosphate streptomyces coelicolor 1.4 1.4 1 PMID:11408165 -2.7.7.60 ctp arabidopsis thaliana 26.0 26.0 1 PMID:10841550 -2.7.7.60 ctp bacillus subtilis 71.24 71.24 1 PMID:27821871 -2.7.7.60 ctp escherichia coli 79.5 54.1 3 PMID:10841550;PMID:15379557;PMID:27821871 -2.7.7.60 ctp francisella tularensis 0.8 0.8 1 PMID:21694781 -2.7.7.60 ctp mycobacterium tuberculosis 3.4 3.4 1 PMID:18047786 -2.7.7.60 ctp plasmodium falciparum 11.7 11.7 1 PMID:29072835 -2.7.7.60 ctp streptomyces coelicolor 6.0 6.0 1 PMID:11408165 -2.7.7.62 5'-deoxyadenosylcobinamide phosphate salmonella enterica subsp. enterica serovar typhimurium 0.093 0.093 1 PMID:7559521 -2.7.7.62 adenosylcobinamide phosphate methanocaldococcus jannaschii 4.7 4.7 1 PMID:19489548 -2.7.7.62 gtp methanocaldococcus jannaschii 1.8 1.8 1 PMID:19489548 -2.7.7.62 gtp salmonella enterica subsp. enterica serovar typhimurium 0.058 0.058 1 PMID:7559521 -2.7.7.64 alpha-d-galactose 1-phosphate leishmania major 216.45 216.45 1 PMID:30871023 -2.7.7.64 d-galactose 1-phosphate arabidopsis thaliana 133.0 133.0 1 PMID:17341835 -2.7.7.64 d-galactose 1-phosphate leishmania major 219.0 219.0 2 PMID:19906649 -2.7.7.64 d-galactose 1-phosphate trypanosoma cruzi 35.2 35.2 1 PMID:20482518 -2.7.7.64 d-glucose 1-phosphate arabidopsis thaliana 122.0 122.0 1 PMID:17341835 -2.7.7.64 d-glucose 1-phosphate leishmania major 191.0 191.0 2 PMID:19906649 -2.7.7.64 d-glucose 1-phosphate populus deltoides 0.008 0.008 1 * -2.7.7.64 d-glucose 1-phosphate trypanosoma cruzi 26.0 13.06 2 PMID:20482518 -2.7.7.64 d-glucuronic acid 1-phosphate arabidopsis thaliana 67.0 67.0 1 PMID:17341835 -2.7.7.64 d-xylose 1-phosphate arabidopsis thaliana 51.0 51.0 1 PMID:17341835 -2.7.7.64 d-xylose 1-phosphate trypanosoma cruzi 8.6 8.6 1 PMID:20482518 -2.7.7.64 diphosphate arabidopsis thaliana 138.0 138.0 1 PMID:17341835 -2.7.7.64 diphosphate leishmania major 185.0 127.5 8 PMID:19906649 -2.7.7.64 dttp arabidopsis thaliana 27.0 27.0 1 PMID:23707255 -2.7.7.64 dutp arabidopsis thaliana 219.0 219.0 1 PMID:23707255 -2.7.7.64 l-arabinose 1-phosphate arabidopsis thaliana 138.0 138.0 1 PMID:17341835 -2.7.7.64 n-acetylglucosamine 1-phosphate thermus caldophilus 0.2 0.2 1 PMID:9889080 -2.7.7.64 ttp trypanosoma cruzi 0.085 0.085 1 PMID:20482518 -2.7.7.64 udp-alpha-d-galacturonate leishmania major 13.0 13.0 1 PMID:19906649 -2.7.7.64 udp-beta-l-arabinopyranose leishmania major 72.0 72.0 1 PMID:19906649 -2.7.7.64 udp-d-galactose leishmania major 154.0 154.0 1 PMID:19906649 -2.7.7.64 udp-d-galacturonate leishmania major 13.0 13.0 1 PMID:19906649 -2.7.7.64 udp-d-glucose leishmania major 180.0 180.0 1 PMID:19906649 -2.7.7.64 udp-galactose leishmania major 154.0 154.0 1 PMID:19906649 -2.7.7.64 udp-glucose arabidopsis thaliana 133.0 133.0 1 PMID:17341835 -2.7.7.64 udp-glucose leishmania major 180.0 180.0 1 PMID:19906649 -2.7.7.64 udp-l-arabinopyranose leishmania major 72.0 72.0 1 PMID:19906649 -2.7.7.64 utp arabidopsis thaliana 348.0 228.0 2 PMID:17341835;PMID:23707255 -2.7.7.64 utp leishmania major 209.0 205.0 4 PMID:19906649 -2.7.7.64 utp populus deltoides 0.003 0.003 1 * -2.7.7.64 utp thermus caldophilus 0.4 0.4 1 PMID:9889080 -2.7.7.65 cyclic di-3',5'-guanylate caulobacter vibrioides 0.0009 0.0009 1 PMID:17697997 -2.7.7.65 gtp escherichia coli 0.02 0.02 1 PMID:31520879 -2.7.7.65 gtp leptospira interrogans serovar copenhageni str. fiocruz l1-130 0.13 0.13 1 PMID:28601495 -2.7.7.65 gtp pseudomonas syringae 59.05 40.56 3 PMID:19695263 -2.7.7.65 gtp rhodococcus ruber 1.3 1.3 1 PMID:31195084 -2.7.7.65 gtp xanthomonas citri pv. citri 1.2 1.2 1 PMID:25463434 -2.7.7.67 2,3-bis-(o-geranylgeranyl)-sn-glycerol 1-phosphate archaeoglobus fulgidus 0.55 0.55 1 PMID:25219966 -2.7.7.69 alpha-d-galactose 1-phosphate arabidopsis thaliana 6.0 3.8 3 PMID:17462988;PMID:18463094 -2.7.7.69 alpha-d-glucose 1-phosphate arabidopsis thaliana 12.0 8.9 2 PMID:17462988;PMID:18463094 -2.7.7.69 alpha-d-mannose 1-phosphate arabidopsis thaliana 0.0012 0.0012 1 PMID:17462988 -2.7.7.69 alpha-l-galactose 1-phosphate arabidopsis thaliana 6.0 6.0 2 PMID:17462988;PMID:18463094 -2.7.7.69 gdp-alpha-d-glucose arabidopsis thaliana 23.0 16.45 2 PMID:17462988;PMID:18463094 -2.7.7.69 gdp-alpha-d-mannose arabidopsis thaliana 0.093 0.058499999999999996 2 PMID:17462988;PMID:18463094 -2.7.7.69 gdp-alpha-l-galactose arabidopsis thaliana 64.0 13.0 5 PMID:17462988;PMID:17877701;PMID:18463094 -2.7.7.7 2-aminopurine-2'-deoxy-d-ribose 5'-triphosphate saccharolobus solfataricus 0.34 0.315 2 PMID:16116089 -2.7.7.7 2-thio-dctp saccharolobus solfataricus 0.04 0.035 2 PMID:23959784 -2.7.7.7 5-ethynyl-dctp geobacillus stearothermophilus 10.4 10.4 1 PMID:27668519 -2.7.7.7 5-ethynyl-dutp geobacillus stearothermophilus 4.6 4.6 1 PMID:27668519 -2.7.7.7 5-methyl-dctp saccharolobus solfataricus 0.33 0.17500000000000002 2 PMID:23959784 -2.7.7.7 5-phenyl-dctp geobacillus stearothermophilus 7.5 7.5 1 PMID:27668519 -2.7.7.7 5-phenyl-dutp geobacillus stearothermophilus 9.3 9.3 1 PMID:27668519 -2.7.7.7 5-vinyl-dctp geobacillus stearothermophilus 15.4 15.4 1 PMID:27668519 -2.7.7.7 5-vinyl-dutp geobacillus stearothermophilus 17.7 17.7 1 PMID:27668519 -2.7.7.7 7-deaza-2'-deoxyadenosine 5'-triphosphate saccharolobus solfataricus 0.405 0.2 5 PMID:16116089 -2.7.7.7 7-deaza-dgtp geobacillus stearothermophilus 12.1 12.1 1 PMID:27668519 -2.7.7.7 7-ethynyl-7-deaza-datp geobacillus stearothermophilus 6.3 6.3 1 PMID:27668519 -2.7.7.7 7-ethynyl-7-deaza-dgtp geobacillus stearothermophilus 17.5 17.5 1 PMID:27668519 -2.7.7.7 7-methyl-7-deaza-datp geobacillus stearothermophilus 5.5 5.5 1 PMID:27668519 -2.7.7.7 7-methyl-7-deaza-dgtp geobacillus stearothermophilus 12.7 12.7 1 PMID:27668519 -2.7.7.7 7-phenyl-7-deaza-datp geobacillus stearothermophilus 13.5 13.5 1 PMID:27668519 -2.7.7.7 7-phenyl-7-deaza-dgtp geobacillus stearothermophilus 13.7 13.7 1 PMID:27668519 -2.7.7.7 7-vinyl-7-deaza-datp geobacillus stearothermophilus 7.1 7.1 1 PMID:27668519 -2.7.7.7 7-vinyl-7-deaza-dgtp geobacillus stearothermophilus 13.8 13.8 1 PMID:27668519 -2.7.7.7 cy3-datp escherichia coli 1.16 1.16 1 PMID:29036327 -2.7.7.7 cy3-dctp escherichia coli 1.75 1.75 1 PMID:29036327 -2.7.7.7 cy3-dgtp escherichia coli 1.64 1.64 1 PMID:29036327 -2.7.7.7 cy3-dutp escherichia coli 1.57 1.57 1 PMID:29036327 -2.7.7.7 dadp thermus aquaticus 6.0 6.0 1 PMID:29339523 -2.7.7.7 datp escherichia coli 1.69 1.69 1 PMID:29036327 -2.7.7.7 datp geobacillus anatolicus 0.4 0.2925 2 PMID:22652043 -2.7.7.7 datp geobacillus stearothermophilus 8.0 8.0 1 PMID:27668519 -2.7.7.7 datp pyrococcus furiosus 0.22 0.22 1 PMID:19817489 -2.7.7.7 datp saccharolobus solfataricus 2.5 0.011 29 PMID:16116089;PMID:16223720;PMID:16306039;PMID:19397282;PMID:19607842;PMID:21784862;PMID:22793782;PMID:23050956 -2.7.7.7 datp saccharomyces cerevisiae 0.14 0.14 1 PMID:15778218 -2.7.7.7 datp thermococcus litoralis 0.043 0.00605 6 PMID:22793782 -2.7.7.7 dctp escherichia coli 1.75 1.75 1 PMID:29036327 -2.7.7.7 dctp geobacillus stearothermophilus 6.1 6.1 1 PMID:27668519 -2.7.7.7 dctp saccharolobus solfataricus 12.0 0.013999999999999999 30 PMID:16223720;PMID:16306039;PMID:19397282;PMID:19607842;PMID:21784862;PMID:22793782;PMID:23701509;PMID:23959784 -2.7.7.7 dctp saccharomyces cerevisiae 0.16 0.16 1 PMID:15778218 -2.7.7.7 dctp thermococcus litoralis 0.065 0.01205 6 PMID:22793782 -2.7.7.7 deoxynucleoside triphosphate [bacillus] caldotenax 1.05 1.05 1 * -2.7.7.7 deoxynucleoside triphosphate enterobacteria phage prd1 4.0 4.0 1 PMID:7918621 -2.7.7.7 deoxynucleoside triphosphate thermococcus pacificus 116.0 104.0 2 * -2.7.7.7 deoxynucleoside triphosphate thermococcus waiotapuensis 3.9 3.9 1 PMID:25039058 -2.7.7.7 deoxynucleoside triphosphate thermus aquaticus 0.0667 0.0667 1 PMID:10827184 -2.7.7.7 deoxynucleoside triphosphate thermus thermophilus 0.0667 0.0667 1 PMID:10827184 -2.7.7.7 dgtp escherichia coli 6.48 6.48 1 PMID:29036327 -2.7.7.7 dgtp geobacillus stearothermophilus 13.1 13.1 1 PMID:27668519 -2.7.7.7 dgtp saccharolobus solfataricus 3.7 0.0039 20 PMID:16223720;PMID:16306039;PMID:19397282;PMID:19607842;PMID:21784862;PMID:22793782 -2.7.7.7 dgtp thermococcus litoralis 0.043 0.0052 5 PMID:22793782 -2.7.7.7 dnan thermococcus pacificus 13.6 13.25 2 * -2.7.7.7 dnan thermococcus waiotapuensis 2.6 2.6 1 PMID:25039058 -2.7.7.7 dntp [bacillus] caldotenax 1.0 1.0 1 * -2.7.7.7 dptp saccharolobus solfataricus 0.05 0.05 1 PMID:23959784 -2.7.7.7 dttp danio rerio 0.0123 0.01095 2 PMID:22018137 -2.7.7.7 dttp escherichia coli 6.57 6.57 1 PMID:29036327 -2.7.7.7 dttp geobacillus anatolicus 175.0 50.699999999999996 4 PMID:22652043 -2.7.7.7 dttp saccharolobus solfataricus 0.64 0.025 24 PMID:16223720;PMID:19397282;PMID:19607842;PMID:21784862;PMID:22793782;PMID:23701509 -2.7.7.7 dttp thermococcus litoralis 0.043 0.012 7 PMID:22793782 -2.7.7.7 dttp thermus thermophilus 1.0 1.0 1 PMID:23026053 -2.7.7.7 n1-methyl-2'-deoxyadenosine 5'-triphosphate saccharolobus solfataricus 0.15 0.063 5 PMID:16116089 -2.7.7.7 north-methanocarba-datp saccharolobus solfataricus 0.08 0.047 2 PMID:23050956 -2.7.7.7 nucleotide escherichia coli 250.0 16.7 3 * -2.7.7.7 primed m13 streptococcus pneumoniae 0.011 0.011 1 PMID:9523721 -2.7.7.7 ratp saccharomyces cerevisiae 0.072 0.072 1 PMID:15778218 -2.7.7.7 rctp saccharomyces cerevisiae 0.09 0.09 1 PMID:15778218 -2.7.7.7 south-methanocarba-datp saccharolobus solfataricus 0.0088 0.0088 1 PMID:23050956 -2.7.7.7 ttp geobacillus stearothermophilus 6.6 6.6 1 PMID:27668519 -2.7.7.71 alpha-d-mannose 1-phosphate yersinia pseudotuberculosis 0.56 0.56 1 PMID:31613705 -2.7.7.71 d-glucose 1-phosphate burkholderia pseudomallei 0.0117 0.0117 1 PMID:28280867 -2.7.7.71 gtp burkholderia pseudomallei 0.0107 0.0107 1 PMID:28280867 -2.7.7.71 gtp yersinia pseudotuberculosis 3.22 3.22 1 PMID:31613705 -2.7.7.72 a trna precursor homo sapiens 0.09 0.09 1 PMID:25849199 -2.7.7.72 armless trna(arg) precursor homo sapiens 0.041 0.022000000000000002 2 PMID:33260740 -2.7.7.72 armless trna(arg) precursor romanomermis culicivorax 0.081 0.0465 2 PMID:33260740 -2.7.7.72 armless trna(ile) precursor homo sapiens 0.165 0.0855 2 PMID:33260740 -2.7.7.72 armless trna(ile) precursor romanomermis culicivorax 0.224 0.138 2 PMID:33260740 -2.7.7.72 atp archaeoglobus fulgidus 2.56 2.56 1 PMID:18495940 -2.7.7.72 atp bacillus subtilis 0.69 0.201 3 PMID:29099323 -2.7.7.72 atp exiguobacterium artemiae 0.149 0.11449999999999999 2 PMID:29099323 -2.7.7.72 atp geobacillus stearothermophilus 1.58 0.092 3 PMID:29099323 -2.7.7.72 atp planococcus halocryophilus 0.14 0.1215 2 PMID:29099323 -2.7.7.72 atp saccharolobus shibatae 0.035 0.035 1 PMID:11926813 -2.7.7.72 ctp archaeoglobus fulgidus 3.68 3.4450000000000003 2 PMID:18495940 -2.7.7.72 ctp saccharolobus shibatae 0.0027 0.0027 1 PMID:11926813 -2.7.7.72 diphosphate escherichia coli 3.1 1.9 3 PMID:22001019 -2.7.7.72 trna(phe) precursor homo sapiens 0.214 0.1525 2 PMID:33260740 -2.7.7.72 trna(phe) precursor romanomermis culicivorax 0.166 0.10350000000000001 2 PMID:33260740 -2.7.7.72 trnahis+g-1 saccharomyces cerevisiae 0.418 0.418 1 PMID:30893886 -2.7.7.72 trnahisdeltag-1 saccharomyces cerevisiae 0.458 0.458 1 PMID:30893886 -2.7.7.75 atp arabidopsis thaliana 0.0012 0.0012 1 PMID:15504727 -2.7.7.76 ctp escherichia coli 0.0062 0.0046 2 PMID:19542235 -2.7.7.77 gtp escherichia coli 0.0048 0.0048 1 PMID:21081498 -2.7.7.78 gdp-alpha-d-glucose caenorhabditis elegans 265.0 265.0 1 PMID:21507950 -2.7.7.78 gdp-alpha-d-glucose homo sapiens 26.0 26.0 1 PMID:21507950 -2.7.7.78 phosphate caenorhabditis elegans 380.0 380.0 1 PMID:21507950 -2.7.7.78 phosphate homo sapiens 28.1 28.1 1 PMID:21507950 -2.7.7.79 p-trnahis saccharomyces cerevisiae 0.0122 0.0122 1 PMID:16625026 -2.7.7.79 ppp-trnahis saccharomyces cerevisiae 0.00089 0.00089 1 PMID:18366186 -2.7.7.79 ppp-trnaphe saccharomyces cerevisiae 0.00012 0.00012 1 PMID:18366186 -2.7.7.8 adp staphylococcus epidermidis 1.22 1.22 1 PMID:29242153 -2.7.7.8 poly(a)n staphylococcus epidermidis 15.88 15.88 1 PMID:29242153 -2.7.7.8 polyadenylic acid thermus thermophilus 75.0 39.165 2 PMID:891551 -2.7.7.8 polycytidylic acid thermus thermophilus 3.33 3.33 1 PMID:891551 -2.7.7.8 polyguanylic acid thermus thermophilus 3.33 3.33 1 PMID:891551 -2.7.7.8 polyuridylic acid thermus thermophilus 3.33 3.33 1 PMID:891551 -2.7.7.84 atp sus scrofa 8.1 8.1 1 PMID:14636576 -2.7.7.84 nad+ sus scrofa 3.6 3.6 1 PMID:14636576 -2.7.7.9 alpha-d-glucose 1-phosphate caenorhabditis elegans 23.58 23.24 3 PMID:27009306 -2.7.7.9 alpha-d-glucose 1-phosphate ganoderma lucidum 33.11 33.11 1 PMID:26235043 -2.7.7.9 alpha-d-glucose 1-phosphate mycobacterium tuberculosis 55.03 55.03 1 PMID:18621545 -2.7.7.9 alpha-d-glucose 1-phosphate pyrococcus horikoshii 6.18 6.18 1 PMID:29806742 -2.7.7.9 alpha-d-glucose 1-phosphate streptococcus equi 48.81 48.81 1 PMID:21104023 -2.7.7.9 alpha-d-glucose 1-phosphate sulfurisphaera tokodaii 2.97 2.97 1 PMID:27864169 -2.7.7.9 alpha-d-glucose 1-phosphate synechocystis sp. 0.45 0.45 1 PMID:24727225 -2.7.7.9 alpha-d-glucose 1-phosphate thermocrispum agreste 598.0 598.0 1 PMID:32714915 -2.7.7.9 atp pyrococcus horikoshii 1.8 1.1 2 PMID:29806742 -2.7.7.9 ctp pyrococcus horikoshii 1.8 1.04 2 PMID:29806742 -2.7.7.9 diphosphate nostoc sp. 6.35 6.35 1 PMID:24231376 -2.7.7.9 dttp caenorhabditis elegans 28.2 28.2 1 PMID:27009306 -2.7.7.9 dttp pyrococcus horikoshii 2.0 1.185 2 PMID:29806742 -2.7.7.9 farnesyl triphosphate saccharomyces cerevisiae 0.033 0.033 1 PMID:22580055 -2.7.7.9 geranyl triphosphate saccharomyces cerevisiae 0.038 0.038 1 PMID:22580055 -2.7.7.9 gtp pyrococcus horikoshii 2.5 1.43 2 PMID:29806742 -2.7.7.9 isopentenyl triphosphate saccharomyces cerevisiae 0.013 0.013 1 PMID:22580055 -2.7.7.9 methylenebisphosphonate saccharomyces cerevisiae 27.0 27.0 1 PMID:22580055 -2.7.7.9 ttp xanthomonas campestris pv. campestris 6.8 6.8 1 PMID:18926872 -2.7.7.9 ttp xanthomonas citri 10.0 10.0 1 PMID:18926872 -2.7.7.9 udp-glucose ganoderma lucidum 0.21 0.21 1 PMID:26235043 -2.7.7.9 udp-glucose gracilaria chouae 19.98 19.98 1 * -2.7.7.9 udp-glucose saccharina japonica 19.98 19.98 1 * -2.7.7.9 utp caenorhabditis elegans 21.92 20.97 2 PMID:27009306 -2.7.7.9 utp mycobacterium tuberculosis 93.44 93.44 1 PMID:18621545 -2.7.7.9 utp nostoc sp. 0.6 0.6 1 PMID:24231376 -2.7.7.9 utp pyrococcus horikoshii 12.1 7.1 2 PMID:29806742 -2.7.7.9 utp streptococcus equi 69.05 69.05 1 PMID:21104023 -2.7.7.9 utp synechocystis sp. 0.47 0.47 1 PMID:24727225 -2.7.7.9 utp thermocrispum agreste 914.0 914.0 1 PMID:32714915 -2.7.7.9 utp xanthomonas campestris pv. campestris 40.0 40.0 1 PMID:18926872 -2.7.7.9 utp xanthomonas citri 29.3 29.3 1 PMID:18926872 -2.7.7.92 ctp bacteroides thetaiotaomicron 1.02 1.02 1 PMID:18804026 -2.7.7.97 3-hydroxy-4-methylanthranilate streptomyces anulatus 0.0032 0.0032 1 PMID:1318300 -2.7.7.97 3-hydroxy-4-methylbenzylate streptomyces anulatus 0.007 0.007 1 PMID:1318300 -2.7.7.97 3-hydroxy-anthranilate streptomyces anulatus 0.005 0.005 1 PMID:1318300 -2.7.8.12 cdp-glycerol bacillus subtilis 0.233 0.233 1 PMID:16141206 -2.7.8.13 udp-mur2ac(oyl-l-ala-d-gamma-glu-l-lys-d-ala-d-ala) bacillus subtilis 5.33 5.33 1 PMID:15131133 -2.7.8.13 udp-n-acetylmuramoyl-pentapeptide bacillus subtilis 5.3 5.3 1 PMID:18672909 -2.7.8.13 undecaprenyl phosphate bacillus subtilis 5.33 5.3149999999999995 2 PMID:15131133;PMID:18672909 -2.7.8.17 cathepsin d homo sapiens 0.11 0.07 2 PMID:19955174 -2.7.8.17 dnase i homo sapiens 0.005 0.00475 2 PMID:19955174 -2.7.8.17 man9glcnac1 oligosaccharide homo sapiens 1.55 1.15 2 PMID:19955174 -2.7.8.17 methyl alpha-d-mannopyranoside homo sapiens 0.75 0.625 2 PMID:19955174 -2.7.8.17 npc2 homo sapiens 0.62 0.53 2 PMID:19955174 -2.7.8.17 pro-tripeptidyl peptidase homo sapiens 0.038 0.023 2 PMID:19955174 -2.7.8.17 rnase b homo sapiens 0.05 0.046 2 PMID:19955174 -2.7.8.17 soybean agglutinin homo sapiens 0.005 0.00455 2 PMID:19955174 -2.7.8.17 uteroferrin homo sapiens 0.033 0.022 2 PMID:19955174 -2.7.8.23 carboxyphosphinopyruvate streptomyces hygroscopicus 0.00076 0.00076 1 PMID:1330557 -2.7.8.23 carboxyphosphoenolpyruvate streptomyces hygroscopicus 0.02 0.02 1 PMID:1330557 -2.7.8.26 (4-chloro-3,5-dimethyl-1h-pyrazol-1-yl) (naphthalen-2-yl)methanone salmonella enterica 83.3 83.3 1 PMID:17827296 -2.7.8.26 alpha-ribazole salmonella enterica 0.67 0.67 1 PMID:17827296 -2.7.8.33 ditrans,polycis-undecaprenyl phosphate thermotoga maritima 1.2 1.2 1 PMID:18723618 -2.7.8.33 udp-n-acetyl-d-glucosamine thermotoga maritima 1.2 1.2 1 PMID:18723618 -2.7.8.7 acetoacetyl-coa escherichia coli 0.2 0.2 1 PMID:16788183 -2.7.8.7 acetoacetyl-coa mycoplasmoides pneumoniae 0.001 0.001 1 PMID:16788183 -2.7.8.7 acetoacetyl-coa streptococcus pneumoniae 0.2 0.2 1 PMID:16788183 -2.7.8.7 acetyl-coa escherichia coli 0.4 0.4 1 PMID:16788183 -2.7.8.7 acetyl-coa homo sapiens 0.24 0.24 1 PMID:18022563 -2.7.8.7 acetyl-coa mycoplasmoides pneumoniae 0.009 0.009 1 PMID:16788183 -2.7.8.7 acetyl-coa streptococcus pneumoniae 0.2 0.2 1 PMID:16788183 -2.7.8.7 apo-[acyl-carrier protein] bacillus subtilis 0.0192 0.012150000000000001 4 PMID:26293213 -2.7.8.7 apo-[acyl-carrier protein] escherichia coli 0.7 0.7 1 PMID:16788183 -2.7.8.7 apo-[acyl-carrier protein] mycoplasmoides pneumoniae 0.002 0.002 1 PMID:16788183 -2.7.8.7 apo-[acyl-carrier protein] streptococcus pneumoniae 0.6 0.6 1 PMID:16788183 -2.7.8.7 apo-[bpsa protein] bacillus subtilis 0.035 0.035 1 PMID:21466506 -2.7.8.7 apo-[bpsa protein] pseudomonas aeruginosa 0.683 0.683 1 PMID:21466506 -2.7.8.7 apo-[bpsa protein] pseudomonas putida 0.183 0.183 1 PMID:21466506 -2.7.8.7 apo-[entb-arcp-h6 escherichia coli] bacillus subtilis 1.08 1.08 1 PMID:9484229 -2.7.8.7 apo-[fredericamycin h acyl-carrier protein] streptomyces griseus 0.95 0.85 2 PMID:16895912 -2.7.8.7 apo-[lys2-pcp-h6 saccharomyces cerevisiae] bacillus subtilis 1.17 1.17 1 PMID:9484229 -2.7.8.7 apo-[pcph6srfb1.18] bacillus subtilis 1.73 1.73 1 PMID:9484229 -2.7.8.7 apo-[pcph6srfb2.18] bacillus subtilis 0.933 0.933 1 PMID:9484229 -2.7.8.7 apo-[peptidyl carrier protein] streptomyces verticillus 1.43 0.8065 2 PMID:11451672 -2.7.8.7 apo-[streptomyces sp. frenolicin-acyl-carrier protein] escherichia coli 0.317 0.317 1 PMID:9070424 -2.7.8.7 apo-[streptomyces sp. granaticin-acyl-carrier protein] escherichia coli 0.5 0.5 1 PMID:9070424 -2.7.8.7 apo-[streptomyces sp. oxytetracycline-acyl-carrier protein] escherichia coli 0.167 0.167 1 PMID:9070424 -2.7.8.7 apo-[streptomyces sp. tetracenomycin-acyl-carrier protein(his6)] escherichia coli 0.09 0.09 1 PMID:9070424 -2.7.8.7 apo-acyl-carrier protein bacillus subtilis 2.08 0.2875 6 PMID:11867633;PMID:9484229 -2.7.8.7 apo-acyl-carrier protein escherichia coli 1.67 1.125 4 PMID:10625633;PMID:9070424;PMID:9211277 -2.7.8.7 apo-peptidyl carrier protein bacillus subtilis 1.6 1.6 3 PMID:11867633 -2.7.8.7 butyryl-coa escherichia coli 0.2 0.2 1 PMID:16788183 -2.7.8.7 butyryl-coa mycoplasmoides pneumoniae 0.004 0.004 1 PMID:16788183 -2.7.8.7 butyryl-coa streptococcus pneumoniae 0.3 0.3 1 PMID:16788183 -2.7.8.7 coa escherichia coli 1.0 1.0 1 PMID:16788183 -2.7.8.7 coa mycoplasmoides pneumoniae 0.002 0.002 1 PMID:16788183 -2.7.8.7 coa pseudomonas aeruginosa 2.8 2.8 1 PMID:12381736 -2.7.8.7 coa streptococcus pneumoniae 0.3 0.3 1 PMID:16788183 -2.7.8.7 coa-[4'-phosphopantetheine] bacillus subtilis 0.0027 0.0027 1 PMID:21466506 -2.7.8.7 coa-[4'-phosphopantetheine] pseudomonas aeruginosa 0.075 0.075 1 PMID:21466506 -2.7.8.7 coa-[4'-phosphopantetheine] pseudomonas putida 0.037 0.037 1 PMID:21466506 -2.7.8.7 crotonyl-coa mycoplasmoides pneumoniae 0.005 0.005 1 PMID:16788183 -2.7.8.7 crotonyl-coa streptococcus pneumoniae 0.2 0.2 1 PMID:16788183 -2.7.8.7 decanoyl-coa mycoplasmoides pneumoniae 0.004 0.004 1 PMID:16788183 -2.7.8.7 decanoyl-coa streptococcus pneumoniae 0.5 0.5 1 PMID:16788183 -2.7.8.7 dslefiaskla bacillus subtilis 0.18 0.18 1 PMID:17465518 -2.7.8.7 dslefiaskla escherichia coli 0.013 0.013 1 PMID:17465518 -2.7.8.7 gdsldmlewslm bacillus subtilis 0.004 0.004 1 PMID:17465518 -2.7.8.7 gdsldmlewslm escherichia coli 0.03 0.03 1 PMID:17465518 -2.7.8.7 gdslswllrcln bacillus subtilis 0.17 0.17 1 PMID:17465518 -2.7.8.7 gdslswllrcln escherichia coli 0.001 0.001 1 PMID:17465518 -2.7.8.7 gdslswllrlln bacillus subtilis 0.17 0.17 1 PMID:17465518 -2.7.8.7 gdslswllrlln escherichia coli 0.0005 0.0005 1 PMID:17465518 -2.7.8.7 gdslswllrsln bacillus subtilis 0.14 0.14 1 PMID:17465518 -2.7.8.7 gdslswllrsln escherichia coli 0.0013 0.0013 1 PMID:17465518 -2.7.8.7 gdslswlvrcln bacillus subtilis 0.07 0.07 1 PMID:17465518 -2.7.8.7 gdslswlvrcln escherichia coli 0.0007 0.0007 1 PMID:17465518 -2.7.8.7 gdslswlvrlln bacillus subtilis 0.05 0.05 1 PMID:17465518 -2.7.8.7 gdslswlvrlln escherichia coli 0.0005 0.0005 1 PMID:17465518 -2.7.8.7 malonyl-coa escherichia coli 0.1 0.1 1 PMID:16788183 -2.7.8.7 malonyl-coa mycoplasmoides pneumoniae 0.0004 0.0004 1 PMID:16788183 -2.7.8.7 malonyl-coa streptococcus pneumoniae 0.1 0.1 1 PMID:16788183 -2.7.8.7 mg2+ homo sapiens 0.24 0.24 1 PMID:18022563 -2.7.8.7 myristoleoyl-coa streptococcus pneumoniae 0.5 0.5 1 PMID:16788183 -2.7.8.7 myristoyl-coa mycoplasmoides pneumoniae 0.003 0.003 1 PMID:16788183 -2.7.8.7 myristoyl-coa streptococcus pneumoniae 0.5 0.5 1 PMID:16788183 -2.7.8.7 palmitoleoyl-coa mycoplasmoides pneumoniae 0.003 0.003 1 PMID:16788183 -2.7.8.7 palmitoleoyl-coa streptococcus pneumoniae 0.4 0.4 1 PMID:16788183 -2.7.8.7 palmitoyl-coa streptococcus pneumoniae 0.4 0.4 1 PMID:16788183 -2.7.9.1 amp trypanosoma cruzi 0.12 0.12 1 PMID:27003459 -2.7.9.1 diphosphate trypanosoma cruzi 0.14 0.14 1 PMID:27003459 -2.7.9.1 phosphoenolpyruvate entamoeba histolytica 87.0 80.0 3 PMID:15794763 -2.7.9.1 phosphoenolpyruvate trypanosoma cruzi 0.11 0.11 1 PMID:27003459 -2.7.9.1 pyruvate entamoeba histolytica 15.0 12.5 2 PMID:15794763 -2.7.9.2 amp pyrococcus furiosus 8.7 8.7 1 PMID:11133966 -2.7.9.2 atp pyrococcus furiosus 1330.0 1330.0 1 PMID:11133966 -2.7.9.2 atp saccharolobus solfataricus 0.326 0.28800000000000003 2 * -2.7.9.2 phosphate pyrococcus furiosus 11.9 11.9 1 PMID:11133966 -2.7.9.2 phosphoenolpyruvate pyrococcus furiosus 12.6 12.6 1 PMID:11133966 -2.7.9.2 pyruvate pyrococcus furiosus 1570.0 1570.0 1 PMID:11133966 -2.7.9.2 pyruvate saccharolobus solfataricus 0.48 0.44499999999999995 2 * -2.7.9.2 pyruvate thermoproteus tenax 0.683 0.683 1 PMID:16573681 -2.7.9.4 granular potato starch solanum tuberosum 0.015 0.015 1 PMID:16584202 -2.7.9.6 atp listeria monocytogenes 2.87 2.87 1 PMID:27103605 -2.7.9.6 rifampicin listeria monocytogenes 2.25 2.25 1 PMID:27103605 -2.8.1.1 3-mercaptopyruvate arabidopsis thaliana 54.0 1.2 3 PMID:12482606 -2.8.1.1 cyanide homo sapiens 0.52 0.52 1 PMID:29348167 -2.8.1.1 thiosulfate aquifex aeolicus 400.0 400.0 1 PMID:20060433 -2.8.1.1 thiosulfate arabidopsis thaliana 10.7 4.0 3 PMID:12482606 -2.8.1.1 thiosulfate escherichia coli 260.0 245.0 2 PMID:10735872;PMID:3553189 -2.8.1.2 2-mercaptoethanol homo sapiens 229.0 229.0 1 PMID:23698001 -2.8.1.2 2-mercaptoethanol trichomonas vaginalis 5310.0 5310.0 1 PMID:19762467 -2.8.1.2 3-mercaptopyruvate arabidopsis thaliana 165.0 97.5 2 PMID:10951223 -2.8.1.2 3-mercaptopyruvate escherichia coli 112.0 62.25 2 PMID:4550801 -2.8.1.2 3-mercaptopyruvate homo sapiens 20.9 8.8 5 PMID:25336638 -2.8.1.2 3-mercaptopyruvate rattus norvegicus 25.0 13.015 2 PMID:10506943;PMID:7608189 -2.8.1.2 3-mercaptopyruvate trichomonas vaginalis 2260.0 2260.0 1 PMID:19762467 -2.8.1.2 cyanide homo sapiens 2.4 2.4 1 PMID:23698001 -2.8.1.2 cysteine trichomonas vaginalis 2240.0 2240.0 1 PMID:19762467 -2.8.1.2 dihydrolipoic acid homo sapiens 1.7 1.7 1 PMID:23698001 -2.8.1.2 dithiothreitol homo sapiens 6.1 6.1 1 PMID:23698001 -2.8.1.2 glutathione homo sapiens 0.3 0.3 1 PMID:23698001 -2.8.1.2 l-cysteine homo sapiens 1.1 0.5 3 PMID:23698001;PMID:32179647 -2.8.1.2 l-homocysteine homo sapiens 0.8 0.8 1 PMID:23698001 -2.8.1.2 n-acetyl-l-cysteine homo sapiens 0.27 0.245 2 PMID:32179647 -2.8.1.2 thioredoxin homo sapiens 1.3 0.44 3 PMID:23698001;PMID:32179647 -2.8.1.2 thioredoxin trichomonas vaginalis 172.0 172.0 1 PMID:19762467 -2.8.1.2 thiosulfate trichomonas vaginalis 11.3 11.3 1 PMID:19762467 -2.8.1.3 thiosulfate homo sapiens 0.43 0.43 1 PMID:29348167 -2.8.1.5 dithiothreitol phanerodontia chrysosporium 5.0 5.0 1 PMID:24557072 -2.8.1.6 dethiobiotin arabidopsis thaliana 0.00055 0.00055 1 PMID:11706201 -2.8.1.6 dethiobiotin bacillus subtilis 5e-07 5e-07 1 PMID:12471501 -2.8.1.6 dethiobiotin escherichia coli 13.9 6.9500071000000005 2 PMID:11686925;PMID:12471501 -2.8.1.6 dethiobiotin mycobacterium tuberculosis 0.0016 0.0016 1 PMID:27156617 -2.8.1.7 [sufu]-cysteine bacillus subtilis 0.87 0.87 1 PMID:20822158 -2.8.1.7 l-cysteine azotobacter vinelandii 0.1 0.1 1 PMID:9812986 -2.8.1.7 l-cysteine bacillus subtilis 0.87 0.87 1 PMID:20822158 -2.8.1.7 l-cysteine escherichia coli 0.202 0.202 1 PMID:32133993 -2.8.1.7 l-cysteine lentinula edodes 1.01 1.01 1 PMID:26054293 -2.8.1.7 l-cysteine nostoc sp. pcc 7120 = fachb-418 1.427 0.7815000000000001 2 PMID:28592683 -2.8.1.7 l-cysteine streptomyces lividans 0.5 0.5 2 PMID:17469805 -2.8.1.7 l-cysteine sulfinic acid synechocystis sp. 3.4 3.3 2 PMID:11193410 -2.8.1.7 l-selenocysteine azotobacter vinelandii 0.04 0.04 1 PMID:9812986 -2.8.1.7 l-selenocysteine streptomyces lividans 1.4 1.4 2 PMID:17469805 -2.8.1.7 l-selenocysteine synechocystis sp. 15.0 9.5 2 PMID:11193410 -2.8.1.9 l-cysteine arabidopsis thaliana 0.03 0.03 1 PMID:15561708 -2.8.1.9 l-selenocysteine arabidopsis thaliana 0.357 0.357 1 PMID:15561708 -2.8.2.1 1-hydroxypyrene homo sapiens 2.0 2.0 1 PMID:29038294 -2.8.2.1 2-chlorophenol rattus norvegicus 0.733 0.733 1 PMID:447677 -2.8.2.1 2-naphthol rattus norvegicus 0.9 0.8415 2 PMID:447677;PMID:6948989 -2.8.2.1 3'-phosphoadenylyl sulfate bos taurus 0.141 0.141 1 PMID:33049293 -2.8.2.1 3'-phosphoadenylyl sulfate drosophila melanogaster 40.7 27.0 3 PMID:18256476 -2.8.2.1 3-hydroxyindole rattus norvegicus 0.733 0.6915 2 PMID:447677 -2.8.2.1 4-chlorophenol rattus norvegicus 0.8 0.7335 2 PMID:6948989 -2.8.2.1 4-methoxyphenol rattus norvegicus 2.0 1.775 2 PMID:447677;PMID:6948989 -2.8.2.1 4-nitrophenol canis lupus familiaris 0.15 0.15 1 PMID:14614767 -2.8.2.1 4-nitrophenol drosophila melanogaster 330.0 70.0 3 PMID:18256476 -2.8.2.1 5-hydroxyindole rattus norvegicus 0.65 0.625 2 PMID:447677 -2.8.2.1 5-hydroxytryptamine rattus norvegicus 0.025 0.0175 2 PMID:447677 -2.8.2.1 daidzein homo sapiens 0.1065 0.0055 7 PMID:15499189 -2.8.2.1 daidzein 4'-sulfate homo sapiens 0.063 0.032415 2 PMID:15499189 -2.8.2.1 daidzein 7-sulfate homo sapiens 0.076 0.038079999999999996 2 PMID:15499189 -2.8.2.1 dopamine canis lupus familiaris 0.18 0.18 1 PMID:14614767 -2.8.2.1 genistein homo sapiens 0.124 0.024 7 PMID:15499189 -2.8.2.1 genistein 4'-sulfate homo sapiens 0.035 0.02085 2 PMID:15499189 -2.8.2.1 genistein 7-sulfate homo sapiens 0.06 0.03058 2 PMID:15499189 -2.8.2.1 phenol rattus norvegicus 0.122 0.1175 2 PMID:447677;PMID:6948989 -2.8.2.15 androsterone homo sapiens 0.13 0.13 1 PMID:14573603 -2.8.2.15 dehydroepiandrosterone homo sapiens 0.1 0.1 1 PMID:14573603 -2.8.2.2 1-butanol rattus norvegicus 0.283 0.283 1 PMID:6935986 -2.8.2.2 1-hexanol rattus norvegicus 0.417 0.417 1 PMID:6935986 -2.8.2.2 1-pentanol rattus norvegicus 0.45 0.45 1 PMID:6935986 -2.8.2.2 1-propanol rattus norvegicus 0.183 0.183 1 PMID:6935986 -2.8.2.2 11-deoxycorticosterone rattus norvegicus 0.183 0.183 1 PMID:6935986 -2.8.2.2 2-ethylphenol arabidopsis thaliana 0.000112 0.000112 1 PMID:25736839 -2.8.2.2 2-nitrophenol arabidopsis thaliana 0.000459 0.000459 1 PMID:25736839 -2.8.2.2 2-propanol rattus norvegicus 0.217 0.217 1 PMID:6935986 -2.8.2.2 3-ethylphenol arabidopsis thaliana 5.3e-05 5.3e-05 1 PMID:25736839 -2.8.2.2 3-methyl-1-butanol rattus norvegicus 0.417 0.417 1 PMID:6935986 -2.8.2.2 3-nitrophenol arabidopsis thaliana 0.000389 0.000389 1 PMID:25736839 -2.8.2.2 3beta-hydroxyandrost-5-ene-17-one rattus norvegicus 2.0 2.0 1 PMID:6935986 -2.8.2.2 4-ethylphenol arabidopsis thaliana 0.000109 0.000109 1 PMID:25736839 -2.8.2.2 4-nitrophenol arabidopsis thaliana 0.000545 0.000545 1 PMID:25736839 -2.8.2.2 aldosterone rattus norvegicus 0.133 0.133 1 PMID:6935986 -2.8.2.2 benzyl alcohol homo sapiens 0.013 0.013 2 PMID:26663444 -2.8.2.2 beta-estradiol rattus norvegicus 0.583 0.583 1 PMID:6935986 -2.8.2.2 cortisol rattus norvegicus 0.183 0.183 1 PMID:6935986 -2.8.2.2 cortisone rattus norvegicus 0.15 0.15 1 PMID:6935986 -2.8.2.2 estriol rattus norvegicus 0.167 0.167 1 PMID:6935986 -2.8.2.2 m-cresol arabidopsis thaliana 4e-05 4e-05 1 PMID:25736839 -2.8.2.2 methanol rattus norvegicus 0.0833 0.0833 1 PMID:6935986 -2.8.2.2 o-cresol arabidopsis thaliana 3.5e-05 3.5e-05 1 PMID:25736839 -2.8.2.2 p-cresol arabidopsis thaliana 0.000128 0.000128 1 PMID:25736839 -2.8.2.2 testosterone rattus norvegicus 0.467 0.467 1 PMID:6935986 -2.8.2.20 3'-phosphoadenylyl sulfate drosophila melanogaster 0.11 0.084 2 PMID:23161068 -2.8.2.20 [y+3 peptide]-l-tyrosine homo sapiens 0.065 0.0595 2 PMID:24909447 -2.8.2.20 c4p5y5 peptide homo sapiens 0.00082 0.00082 1 PMID:28821720 -2.8.2.20 gastrin peptide homo sapiens 0.00011 0.00011 1 PMID:28821720 -2.8.2.20 p-selectin glycoprotein ligand-1 drosophila melanogaster 0.1 0.07250000000000001 2 PMID:23161068 -2.8.2.22 4-nitrophenyl sulfate streptomyces sp. 0.14 0.14 1 PMID:20157116 -2.8.2.22 methylumbelliferone sulfate streptomyces sp. 0.15 0.15 1 PMID:20157116 -2.8.2.22 phenol escherichia coli 48.6 48.6 1 PMID:19036922 -2.8.2.37 3'-phosphoadenylyl sulfate mycobacterium tuberculosis 1.6 1.6 1 PMID:15866533 -2.8.2.37 alpha,alpha-trehalose mycobacterium tuberculosis 2.23 2.23 1 PMID:15866533 -2.8.2.37 alpha,alpha-trehalose mycolicibacterium smegmatis 1.6 1.6 1 PMID:15258569 -2.8.2.38 3'-phosphoadenylyl sulfate arabidopsis thaliana 0.0355 0.020649999999999998 2 * -2.8.2.38 desulfobenzylglucosinolate arabidopsis thaliana 0.0352 0.02015 2 * -2.8.2.4 17beta-estradiol homo sapiens 0.0217 0.012185 2 PMID:9556564 -2.8.2.4 4-nitrophenol homo sapiens 0.52 0.52 1 PMID:16899461 -2.8.2.9 2-cyanoethyl-n-hydroxythioacetamide rattus norvegicus 0.0233 0.0233 1 PMID:6946725 -2.8.2.9 2-cyanoethyl-n-hydroxythioacetimidate rattus norvegicus 0.233 0.233 1 PMID:6948989 -2.8.2.9 2-naphthol rattus norvegicus 0.7 0.7 1 PMID:6946725;PMID:6948989 -2.8.2.9 3-chlorophenol rattus norvegicus 0.45 0.45 1 PMID:6946725 -2.8.2.9 3-methoxy-4-hydroxyphenolglycol rattus norvegicus 0.183 0.183 1 PMID:6946725 -2.8.2.9 3-methylphenol rattus norvegicus 0.183 0.183 1 PMID:6946725 -2.8.2.9 3-nitrophenol rattus norvegicus 0.8 0.8 1 PMID:6946725 -2.8.2.9 4-chlorophenol rattus norvegicus 0.317 0.3085 2 PMID:6946725;PMID:6948989 -2.8.2.9 4-methoxyphenol rattus norvegicus 0.45 0.45 1 PMID:6946725;PMID:6948989 -2.8.2.9 4-methylphenol rattus norvegicus 0.02 0.02 1 PMID:6946725 -2.8.2.9 4-nitrophenol rattus norvegicus 0.517 0.517 1 PMID:6946725 -2.8.2.9 5-hydroxytryptophol rattus norvegicus 0.14 0.14 1 PMID:6946725 -2.8.2.9 dopamine rattus norvegicus 0.07 0.07 1 PMID:6946725 -2.8.2.9 epinephrine rattus norvegicus 0.122 0.122 1 PMID:6946725;PMID:6948989 -2.8.2.9 n-acetylserotonin rattus norvegicus 0.3 0.3 1 PMID:6946725 -2.8.2.9 phenol rattus norvegicus 0.03 0.03 1 PMID:6946725 -2.8.2.9 tyramine rattus norvegicus 0.0467 0.0467 1 PMID:6946725;PMID:6948989 -2.8.2.9 tyrosine methyl ester rattus norvegicus 0.233 0.233 1 PMID:6946725;PMID:6948989 -2.8.3.1 propionate anaerotignum propionicum 14.2 14.2 1 PMID:16454529 -2.8.3.10 (3s)-citryl-coa klebsiella aerogenes 26.7 26.7 1 PMID:336371 -2.8.3.10 acetyl-coa klebsiella aerogenes 21.7 21.7 1 PMID:336371 -2.8.3.12 glutaryl-coa acidaminococcus fermentans 140.0 89.5 2 PMID:9089292 -2.8.3.16 formyl-coa acetobacter aceti 4.5 4.5 1 PMID:22374910 -2.8.3.16 formyl-coa oxalobacter formigenes 4.3 4.3 1 PMID:15213226 -2.8.3.16 oxalate acetobacter aceti 5.0 5.0 1 PMID:22374910 -2.8.3.16 oxalate oxalobacter formigenes 4.3 4.3 1 PMID:15213226 -2.8.3.18 acetate acetobacter aceti 280.0 213.5 4 PMID:18502856 -2.8.3.18 acetoacetate acetobacter aceti 36.5 36.5 2 PMID:18502856 -2.8.3.18 acetyl-coa acetobacter aceti 75.2 75.2 2 PMID:18502856 -2.8.3.18 succinate acetobacter aceti 70.9 70.9 2 PMID:18502856 -2.8.3.18 succinyl-coa acetobacter aceti 201.0 201.0 2 PMID:18502856 -2.8.3.19 acetyl-coa escherichia coli 11.0 11.0 1 PMID:23935849 -2.8.3.19 oxalate escherichia coli 15.0 15.0 1 PMID:23935849 -2.8.3.20 (r)-citramalate chloroflexus aurantiacus 13.0 13.0 1 PMID:16952935 -2.8.3.20 succinyl-coa chloroflexus aurantiacus 13.0 13.0 1 PMID:16952935 -2.8.3.22 (s)-malate chloroflexus aurantiacus 11.4 11.4 1 PMID:16547052 -2.8.3.22 succinyl-coa chloroflexus aurantiacus 11.4 11.4 1 PMID:16547052 -2.8.3.23 3,4-dihydroxyphenylpropanoyl-coa acetobacterium woodii 0.008 0.008 1 PMID:23315745 -2.8.3.26 mesaconate haloarcula hispanica 12.2 12.2 1 PMID:28932214 -2.8.3.26 succinyl-coa haloarcula hispanica 12.2 12.2 1 PMID:28932214 -2.8.3.27 propanoyl-coa escherichia coli 0.72 0.72 1 PMID:10769117 -2.8.3.5 acetoacetate sus scrofa 98.3 98.3 1 PMID:17718512 -2.8.3.5 acetoacetyl-coa sus scrofa 1250.0 1091.5 2 PMID:17718512 -2.8.3.5 succinyl-coa sus scrofa 37.3 37.3 1 * -2.8.3.8 acetate acetobacter aceti 290.0 290.0 1 PMID:23030530 -2.8.4.1 cob methanothermobacter marburgensis 18.0 18.0 1 PMID:25691570 -2.8.4.2 arsenate corynebacterium glutamicum 0.6 0.28 8 PMID:19286650;PMID:22032722 -2.8.4.6 dihydrolipoate rhodospirillum rubrum 4.3 4.3 1 PMID:23035785 -2.8.4.6 glutathione rhodospirillum rubrum 0.19 0.19 1 PMID:23035785 -2.8.4.6 l-dithiothreitol rhodospirillum rubrum 7.8 7.8 1 PMID:23035785 -2.8.5.1 3-phospho-l-serine mycobacterium tuberculosis 0.913 0.913 1 PMID:25022854 -2.8.5.1 thiosulfate mycobacterium tuberculosis 0.913 0.913 1 PMID:25022854 -2.9.1.1 selenophosphate escherichia coli 0.0217 0.0217 1 PMID:9688279 -2.9.1.1 thiophosphate escherichia coli 0.000867 0.000867 1 PMID:9688279 -3.1.1.1 (1rs)-cis-permethrin homo sapiens 0.056 0.042 2 PMID:16387282 -3.1.1.1 (1rs)-cis-permethrin oryctolagus cuniculus 0.05 0.05 1 PMID:16387282 -3.1.1.1 (1rs)-cis-permethrin rattus norvegicus 0.0053 0.00465 2 PMID:16387282 -3.1.1.1 (1rs)-trans-permethrin homo sapiens 0.0028 0.0018 2 PMID:16387282 -3.1.1.1 (1rs)-trans-permethrin oryctolagus cuniculus 0.016 0.016 1 PMID:16387282 -3.1.1.1 (1rs)-trans-permethrin rattus norvegicus 0.036 0.0305 2 PMID:16387282 -3.1.1.1 (e)-2-hexenyl acetate spodoptera exigua 26.1 26.1 1 PMID:26267057 -3.1.1.1 (e)-2-hexenyl butyrate spodoptera exigua 22.5 22.5 1 PMID:26267057 -3.1.1.1 (oxolan-2-yl)methyl 2-(4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy)propanoate brevundimonas sp. qpt-2 8.5 8.5 1 * -3.1.1.1 (s)-ketoprofen ethyl ester archaeoglobus fulgidus 65.4 65.4 1 PMID:25661815 -3.1.1.1 (z)-3-hexenyl acetate spodoptera exigua 21.9 21.9 1 PMID:26267057 -3.1.1.1 (z)-3-hexenyl butyrate spodoptera exigua 13.2 13.2 1 PMID:26267057 -3.1.1.1 (z)-3-hexenyl caproate spodoptera exigua 1.9 1.9 1 PMID:26267057 -3.1.1.1 1,4-diacetoxybenzene cereibacter sphaeroides 108.0 108.0 1 PMID:24832101 -3.1.1.1 1-naphthyl acetate agrobacterium tumefaciens 11.6 11.6 1 * -3.1.1.1 1-naphthyl acetate caenorhabditis elegans 500.0 500.0 1 PMID:3651439 -3.1.1.1 1-naphthyl acetate cereibacter sphaeroides 4.8 4.8 1 PMID:24832101 -3.1.1.1 1-naphthyl acetate pseudomonas aeruginosa 3000.0 3000.0 1 PMID:15717224 -3.1.1.1 1-naphthyl butanoate agrobacterium tumefaciens 18.7 18.7 1 * -3.1.1.1 1-naphthyl butanoate pseudomonas aeruginosa 1600.0 1600.0 1 PMID:15717224 -3.1.1.1 1-naphthyl butyrate cereibacter sphaeroides 9.0 9.0 1 PMID:24832101 -3.1.1.1 1-naphthyl butyrate homo sapiens 48.0 48.0 1 PMID:3341748 -3.1.1.1 2,4-dinitrophenyl butyrate equus caballus 64.0 64.0 1 PMID:237618 -3.1.1.1 2,4-dinitrophenyl butyrate ovis aries 173.0 173.0 1 PMID:237618 -3.1.1.1 2,4-dinitrophenyl butyrate sus scrofa 233.0 233.0 1 * -3.1.1.1 2-naphthyl acetate bradysia odoriphaga 0.545 0.545 1 PMID:34596943 -3.1.1.1 2-naphthyl acetate cereibacter sphaeroides 40.0 40.0 1 PMID:24832101 -3.1.1.1 2-naphthyl acetate uncultured bacterium 133.3 133.3 1 PMID:29453256 -3.1.1.1 2-naphthyl propionate cereibacter sphaeroides 83.0 83.0 1 PMID:24832101 -3.1.1.1 2-nitrophenyl butyrate equus caballus 233.0 233.0 1 PMID:237618 -3.1.1.1 2-nitrophenyl butyrate gallus gallus 245.0 245.0 1 PMID:237618 -3.1.1.1 2-nitrophenylacetate equus caballus 1.7 1.7 1 PMID:3196030 -3.1.1.1 2-nitrophenylbutyrate equus caballus 1.4 1.4 1 PMID:3196030 -3.1.1.1 2-nitrophenylpropionate equus caballus 1.3 1.3 1 PMID:3196030 -3.1.1.1 2-phenyloxazolin-5-one equus caballus 111.0 111.0 1 PMID:237618 -3.1.1.1 3'-d-phenylalanyl-gemcitabine sus scrofa 8.7 8.7 1 PMID:16223870 -3.1.1.1 3'-d-valyl-gemcitabine sus scrofa 1.1 1.1 1 PMID:16223870 -3.1.1.1 3'-l-isoleucyl-gemcitabine sus scrofa 0.08 0.08 1 PMID:16223870 -3.1.1.1 3'-l-phenylalanyl-gemcitabine sus scrofa 6.1 6.1 1 PMID:16223870 -3.1.1.1 3'-l-valyl-gemcitabine sus scrofa 0.11 0.11 1 PMID:16223870 -3.1.1.1 3-acetoxypyridine cereibacter sphaeroides 4.3 4.3 1 PMID:24832101 -3.1.1.1 3-nitrophenyl butyrate sus scrofa 345.0 345.0 1 * -3.1.1.1 3-nitrophenylbutyrate equus caballus 1.3 1.3 1 PMID:3196030 -3.1.1.1 4'-chloroacetanilide cereibacter sphaeroides 0.1 0.1 1 PMID:24832101 -3.1.1.1 4-methylbenzyl acetate cereibacter sphaeroides 47.0 47.0 1 PMID:24832101 -3.1.1.1 4-methylumbelliferyl acetate cereibacter sphaeroides 0.65 0.65 1 PMID:24832101 -3.1.1.1 4-methylumbelliferyl acetate uncultured bacterium 166.7 166.7 1 PMID:29453256 -3.1.1.1 4-methylumbelliferyl butanoate actinidia eriantha 10.1 10.1 1 PMID:17256879 -3.1.1.1 4-methylumbelliferyl butyrate cereibacter sphaeroides 4.9 4.9 1 PMID:24832101 -3.1.1.1 4-methylumbelliferyl butyrate malus domestica 69.5 69.5 1 PMID:21315388 -3.1.1.1 4-methylumbelliferyl butyrate pyrococcus furiosus 0.335 0.335 1 PMID:29307486 -3.1.1.1 4-methylumbelliferyl heptanoate actinidia eriantha 2.0 2.0 1 PMID:17256879 -3.1.1.1 4-methylumbelliferyl heptanoate cereibacter sphaeroides 0.063 0.063 1 PMID:24832101 -3.1.1.1 4-methylumbelliferyl heptanoate malus domestica 6.94 6.94 1 PMID:21315388 -3.1.1.1 4-methylumbelliferyl heptanoate pyrococcus furiosus 0.883 0.883 1 PMID:29307486 -3.1.1.1 4-methylumbelliferyl laurate actinidia eriantha 0.01 0.01 1 PMID:17256879 -3.1.1.1 4-methylumbelliferyl laurate malus domestica 6.38 6.38 1 PMID:21315388 -3.1.1.1 4-methylumbelliferyl octanoate actinidia eriantha 0.162 0.162 1 PMID:17256879 -3.1.1.1 4-methylumbelliferyl octanoate malus domestica 4.66 4.66 1 PMID:21315388 -3.1.1.1 4-methylumbelliferyl palmitate actinidia eriantha 0.0018 0.0018 1 PMID:17256879 -3.1.1.1 4-methylumbelliferyl palmitate malus domestica 0.254 0.254 1 PMID:21315388 -3.1.1.1 4-nitroacetanilide cereibacter sphaeroides 0.36 0.36 1 PMID:24832101 -3.1.1.1 4-nitrophenyl acetate agrobacterium tumefaciens 11.8 11.8 1 * -3.1.1.1 4-nitrophenyl acetate alicyclobacillus acidocaldarius 213.0 145.0 3 PMID:8181479 -3.1.1.1 4-nitrophenyl acetate archaeoglobus fulgidus 120.0 120.0 1 PMID:23099882 -3.1.1.1 4-nitrophenyl acetate bacillus velezensis 18.91 18.91 1 PMID:31761671 -3.1.1.1 4-nitrophenyl acetate cereibacter sphaeroides 120.0 120.0 1 PMID:24832101 -3.1.1.1 4-nitrophenyl acetate escherichia coli 18.5 18.5 2 PMID:12732651 -3.1.1.1 4-nitrophenyl acetate ferroplasma acidiphilum 25.0 19.0 2 PMID:16478448;PMID:25043762 -3.1.1.1 4-nitrophenyl acetate geobacillus stearothermophilus 750.0 750.0 1 PMID:7576531 -3.1.1.1 4-nitrophenyl acetate homo sapiens 7.6 7.6 1 PMID:25462813 -3.1.1.1 4-nitrophenyl acetate klebsiella sp. 81.0 81.0 1 PMID:16448191 -3.1.1.1 4-nitrophenyl acetate lacticaseibacillus casei 0.032 0.032 1 PMID:15184114 -3.1.1.1 4-nitrophenyl acetate mus musculus 94.0 94.0 1 PMID:15123619 -3.1.1.1 4-nitrophenyl acetate pseudomonas aeruginosa 6400.0 6400.0 1 PMID:15717224 -3.1.1.1 4-nitrophenyl acetate pyrobaculum sp. 11.65 11.65 1 PMID:25250909 -3.1.1.1 4-nitrophenyl acetate saccharolobus solfataricus 45.3 45.3 2 PMID:15564667 -3.1.1.1 4-nitrophenyl acetate streptomyces lividans 780.6 780.6 1 PMID:33515353 -3.1.1.1 4-nitrophenyl acetate sulfurisphaera tokodaii 74.6 74.6 1 * -3.1.1.1 4-nitrophenyl acetate sus scrofa 20.0 20.0 1 PMID:16223870 -3.1.1.1 4-nitrophenyl acetate uncultured bacterium 492.3 492.3 1 PMID:29453256 -3.1.1.1 4-nitrophenyl acetate uncultured microorganism 1910.0 1910.0 1 PMID:34057548 -3.1.1.1 4-nitrophenyl acetate vulcanisaeta moutnovskia 0.0245 0.0245 1 PMID:25670483 -3.1.1.1 4-nitrophenyl butanoate agrobacterium tumefaciens 10.6 10.6 1 * -3.1.1.1 4-nitrophenyl butanoate alicyclobacillus acidocaldarius 2180.0 1330.0 2 PMID:11447219;PMID:16325466 -3.1.1.1 4-nitrophenyl butanoate archaeoglobus fulgidus 277.0 208.5 2 PMID:16325466;PMID:23099882 -3.1.1.1 4-nitrophenyl butanoate geobacillus stearothermophilus 7.9e-05 7.9e-05 1 PMID:17239398 -3.1.1.1 4-nitrophenyl butanoate homo sapiens 190.0 190.0 1 PMID:16325466 -3.1.1.1 4-nitrophenyl butanoate klebsiella sp. 314.0 314.0 1 PMID:16448191 -3.1.1.1 4-nitrophenyl butanoate lacticaseibacillus casei 0.099 0.099 1 PMID:15184114 -3.1.1.1 4-nitrophenyl butanoate pseudomonas aeruginosa 1700.0 1700.0 1 PMID:15717224 -3.1.1.1 4-nitrophenyl butanoate psychrobacter sp. 110.0 110.0 1 PMID:14726205 -3.1.1.1 4-nitrophenyl butanoate pyrobaculum calidifontis 1690.0 1690.0 1 PMID:12147492 -3.1.1.1 4-nitrophenyl butanoate saccharolobus islandicus 1756.0 803.0 3 PMID:21847512 -3.1.1.1 4-nitrophenyl butanoate sulfurisphaera tokodaii 127.0 127.0 1 PMID:15212797 -3.1.1.1 4-nitrophenyl butyrate alicyclobacillus acidocaldarius 1670.0 1150.0 3 PMID:8181479 -3.1.1.1 4-nitrophenyl butyrate altericroceibacterium indicum 338000.0 338000.0 1 PMID:36756200 -3.1.1.1 4-nitrophenyl butyrate anoxybacillus sp. 1500.0 1500.0 1 PMID:21782026 -3.1.1.1 4-nitrophenyl butyrate archaeoglobus fulgidus 680.0 680.0 1 PMID:10620337 -3.1.1.1 4-nitrophenyl butyrate bacillus sp. scsio 15121 1044.0 1044.0 1 PMID:27364331 -3.1.1.1 4-nitrophenyl butyrate bacillus velezensis 49.42 49.42 1 PMID:31761671 -3.1.1.1 4-nitrophenyl butyrate cereibacter sphaeroides 50.0 50.0 1 PMID:24832101 -3.1.1.1 4-nitrophenyl butyrate equus caballus 144.0 144.0 1 PMID:237618 -3.1.1.1 4-nitrophenyl butyrate escherichia coli 6.1 6.1 2 PMID:12732651 -3.1.1.1 4-nitrophenyl butyrate ferroplasma acidiphilum 56.0 33.0 2 PMID:16478448;PMID:25043762 -3.1.1.1 4-nitrophenyl butyrate geobacillus stearothermophilus 1380.0 1380.0 1 PMID:7576531 -3.1.1.1 4-nitrophenyl butyrate klebsiella sp. 314.0 314.0 1 PMID:16448191 -3.1.1.1 4-nitrophenyl butyrate ovis aries 267.0 267.0 1 PMID:237618 -3.1.1.1 4-nitrophenyl butyrate pyrobaculum sp. 9.12 9.12 1 PMID:25250909 -3.1.1.1 4-nitrophenyl butyrate saccharolobus shibatae 859.0 859.0 1 PMID:25043762 -3.1.1.1 4-nitrophenyl butyrate saccharolobus solfataricus 861.0 432.5 2 PMID:20386955 -3.1.1.1 4-nitrophenyl butyrate streptomyces lividans 729.4 729.4 1 PMID:33515353 -3.1.1.1 4-nitrophenyl butyrate sulfurisphaera tokodaii 127.0 92.95 2 PMID:15212797 -3.1.1.1 4-nitrophenyl butyrate sus scrofa 27.4 27.4 1 PMID:16223870 -3.1.1.1 4-nitrophenyl butyrate uncultured bacterium 15.72 11.695 2 PMID:21908637;PMID:29453256 -3.1.1.1 4-nitrophenyl caprate geobacillus stearothermophilus 800.0 800.0 1 PMID:7576531 -3.1.1.1 4-nitrophenyl caprate lacticaseibacillus casei 0.089 0.089 1 PMID:15184114 -3.1.1.1 4-nitrophenyl caproate bacillus velezensis 13.53 13.53 1 PMID:31761671 -3.1.1.1 4-nitrophenyl caproate escherichia coli 4.0 4.0 2 PMID:12732651 -3.1.1.1 4-nitrophenyl caproate klebsiella sp. 507.0 507.0 1 PMID:16448191 -3.1.1.1 4-nitrophenyl caproate lacticaseibacillus casei 0.119 0.119 1 PMID:15184114 -3.1.1.1 4-nitrophenyl caprylate klebsiella sp. 360.0 360.0 1 PMID:16448191 -3.1.1.1 4-nitrophenyl caprylate lacticaseibacillus casei 0.125 0.125 1 PMID:15184114 -3.1.1.1 4-nitrophenyl caprylate saccharolobus solfataricus 1.7 1.7 1 PMID:20386955 -3.1.1.1 4-nitrophenyl decanoate alicyclobacillus acidocaldarius 950.0 950.0 1 PMID:11447219 -3.1.1.1 4-nitrophenyl decanoate archaeoglobus fulgidus 477.0 477.0 1 PMID:23099882 -3.1.1.1 4-nitrophenyl decanoate pyrobaculum sp. 6.19 6.19 1 PMID:25250909 -3.1.1.1 4-nitrophenyl decanoate saccharolobus islandicus 1124.0 526.0 3 PMID:21847512 -3.1.1.1 4-nitrophenyl decanoate saccharolobus solfataricus 2337.0 2337.0 1 * -3.1.1.1 4-nitrophenyl decanoate sulfurisphaera tokodaii 1.5 1.5 1 * -3.1.1.1 4-nitrophenyl dodecanoate aeropyrum pernix 1.35 1.35 1 PMID:21748600 -3.1.1.1 4-nitrophenyl dodecanoate alicyclobacillus acidocaldarius 390.0 390.0 1 PMID:11447219 -3.1.1.1 4-nitrophenyl dodecanoate archaeoglobus fulgidus 128.0 128.0 1 PMID:23099882 -3.1.1.1 4-nitrophenyl dodecanoate klebsiella sp. 59.0 59.0 1 PMID:16448191 -3.1.1.1 4-nitrophenyl dodecanoate saccharolobus solfataricus 1312.0 78.0 3 PMID:15564667 -3.1.1.1 4-nitrophenyl dodecanoate sulfurisphaera tokodaii 0.2 0.2 1 * -3.1.1.1 4-nitrophenyl hexadecanoate alicyclobacillus acidocaldarius 21.0 21.0 1 PMID:11447219 -3.1.1.1 4-nitrophenyl hexadecanoate archaeoglobus fulgidus 5.3 5.3 1 PMID:23099882 -3.1.1.1 4-nitrophenyl hexadecanoate saccharolobus solfataricus 1138.0 3.8 3 PMID:15564667 -3.1.1.1 4-nitrophenyl hexadecanoate sulfurisphaera tokodaii 0.03 0.03 1 * -3.1.1.1 4-nitrophenyl hexanoate alicyclobacillus acidocaldarius 3420.0 1440.0 4 PMID:11447219;PMID:8181479 -3.1.1.1 4-nitrophenyl hexanoate altericroceibacterium indicum 431000.0 431000.0 1 PMID:36756200 -3.1.1.1 4-nitrophenyl hexanoate archaeoglobus fulgidus 1014.0 1014.0 1 PMID:10620337 -3.1.1.1 4-nitrophenyl hexanoate cereibacter sphaeroides 6.5 6.5 1 PMID:24832101 -3.1.1.1 4-nitrophenyl hexanoate ferroplasma acidiphilum 11.0 6.5 2 PMID:16478448;PMID:25043762 -3.1.1.1 4-nitrophenyl hexanoate geobacillus stearothermophilus 1550.0 1550.0 1 PMID:7576531 -3.1.1.1 4-nitrophenyl hexanoate klebsiella sp. 507.0 507.0 1 PMID:16448191 -3.1.1.1 4-nitrophenyl hexanoate mus musculus 31.0 21.5 2 PMID:6788549;PMID:7160378 -3.1.1.1 4-nitrophenyl hexanoate psychrobacter sp. 58.0 58.0 1 PMID:14726205 -3.1.1.1 4-nitrophenyl hexanoate pyrobaculum calidifontis 2620.0 2620.0 1 PMID:12147492 -3.1.1.1 4-nitrophenyl hexanoate saccharolobus islandicus 2003.0 1228.0 3 PMID:21847512 -3.1.1.1 4-nitrophenyl hexanoate saccharolobus solfataricus 1476.0 777.65 2 PMID:15564667 -3.1.1.1 4-nitrophenyl hexanoate streptomyces lividans 297.2 297.2 1 PMID:33515353 -3.1.1.1 4-nitrophenyl hexanoate sulfurisphaera tokodaii 44.7 44.7 1 PMID:15212797 -3.1.1.1 4-nitrophenyl laurate escherichia coli 1.5 1.5 2 PMID:12732651 -3.1.1.1 4-nitrophenyl laurate geobacillus stearothermophilus 555.0 555.0 1 PMID:7576531 -3.1.1.1 4-nitrophenyl laurate klebsiella sp. 59.0 59.0 1 PMID:16448191 -3.1.1.1 4-nitrophenyl laurate lacticaseibacillus casei 0.024 0.024 1 PMID:15184114 -3.1.1.1 4-nitrophenyl octanoate aeropyrum pernix 8.67 8.67 1 PMID:21084296 -3.1.1.1 4-nitrophenyl octanoate alicyclobacillus acidocaldarius 1960.0 1055.5 4 PMID:11447219;PMID:8181479 -3.1.1.1 4-nitrophenyl octanoate archaeoglobus fulgidus 831.0 800.5 2 PMID:10620337;PMID:23099882 -3.1.1.1 4-nitrophenyl octanoate cereibacter sphaeroides 0.5 0.5 1 PMID:24832101 -3.1.1.1 4-nitrophenyl octanoate geobacillus stearothermophilus 1250.0 1250.0 1 PMID:7576531 -3.1.1.1 4-nitrophenyl octanoate klebsiella sp. 360.0 360.0 1 PMID:16448191 -3.1.1.1 4-nitrophenyl octanoate niallia circulans 51.0 51.0 1 PMID:10968629 -3.1.1.1 4-nitrophenyl octanoate psychrobacter sp. 24.0 24.0 1 PMID:14726205 -3.1.1.1 4-nitrophenyl octanoate pyrobaculum calidifontis 1600.0 1600.0 1 PMID:12147492 -3.1.1.1 4-nitrophenyl octanoate pyrobaculum sp. 6.36 6.36 1 PMID:25250909 -3.1.1.1 4-nitrophenyl octanoate saccharolobus solfataricus 1491.0 785.15 2 PMID:15564667 -3.1.1.1 4-nitrophenyl octanoate sulfurisphaera tokodaii 25.2 23.15 2 PMID:15212797 -3.1.1.1 4-nitrophenyl palmitate archaeoglobus fulgidus 47.5 47.5 1 PMID:16086253 -3.1.1.1 4-nitrophenyl palmitate bos taurus 0.424 0.21359 2 * -3.1.1.1 4-nitrophenyl palmitate saccharolobus islandicus 1080.0 296.0 3 PMID:21847512 -3.1.1.1 4-nitrophenyl pentanoate alicyclobacillus acidocaldarius 2050.0 1400.0 3 PMID:8181479 -3.1.1.1 4-nitrophenyl pentanoate archaeoglobus fulgidus 866.0 866.0 1 PMID:10620337 -3.1.1.1 4-nitrophenyl pentanoate geobacillus stearothermophilus 15300.0 15300.0 1 PMID:7576531 -3.1.1.1 4-nitrophenyl pentanoate pyrobaculum calidifontis 2070.0 2070.0 1 PMID:12147492 -3.1.1.1 4-nitrophenyl pentanoate saccharolobus solfataricus 46.3 46.3 2 PMID:15564667 -3.1.1.1 4-nitrophenyl propanoate klebsiella sp. 238.0 238.0 1 PMID:16448191 -3.1.1.1 4-nitrophenyl propanoate pyrobaculum calidifontis 1480.0 1480.0 1 PMID:12147492 -3.1.1.1 4-nitrophenyl propionate alicyclobacillus acidocaldarius 1230.0 1000.0 3 PMID:8181479 -3.1.1.1 4-nitrophenyl propionate archaeoglobus fulgidus 348.0 348.0 1 PMID:10620337 -3.1.1.1 4-nitrophenyl propionate escherichia coli 13.1 13.1 2 PMID:12732651 -3.1.1.1 4-nitrophenyl propionate ferroplasma acidiphilum 29.0 18.5 2 PMID:16478448;PMID:25043762 -3.1.1.1 4-nitrophenyl propionate geobacillus stearothermophilus 1170.0 1170.0 1 PMID:7576531 -3.1.1.1 4-nitrophenyl propionate klebsiella sp. 238.0 238.0 1 PMID:16448191 -3.1.1.1 4-nitrophenyl propionate mus musculus 230.0 230.0 1 PMID:28771 -3.1.1.1 4-nitrophenyl propionate niallia circulans 144.0 144.0 1 PMID:10968629 -3.1.1.1 4-nitrophenyl tetradecanoate archaeoglobus fulgidus 42.3 42.3 1 PMID:23099882 -3.1.1.1 4-nitrophenyl tetradecanoate sulfurisphaera tokodaii 0.11 0.11 1 * -3.1.1.1 4-nitrophenyl valerate bacillus subtilis 580.0 580.0 1 PMID:18163883 -3.1.1.1 4-nitrophenyl valerate psychrobacter sp. 110.0 110.0 1 PMID:14726205 -3.1.1.1 4-nitrophenylbutyrate equus caballus 1.6 1.6 1 PMID:3196030 -3.1.1.1 4-yethylumbelliferyl acetate actinidia eriantha 1.61 1.61 1 PMID:17256879 -3.1.1.1 4-yethylumbelliferyl acetate bacillus subtilis 140.0 140.0 1 PMID:18163883 -3.1.1.1 4-yethylumbelliferyl acetate malus domestica 3.7 3.7 1 PMID:21315388 -3.1.1.1 4-yethylumbelliferyl acetate pseudomonas aeruginosa 8500.0 8500.0 1 PMID:15717224 -3.1.1.1 4-yethylumbelliferyl acetate pseudomonas aeruginosa pao1 8500.0 8500.0 1 PMID:15717224 -3.1.1.1 4-yethylumbelliferyl acetate saccharolobus solfataricus 1000.0 1000.0 1 PMID:11210525 -3.1.1.1 5'-cinnamic acid-floxuridine sus scrofa 1.38 1.38 1 PMID:16223870 -3.1.1.1 5'-d-phenylalanyl-bdcrb sus scrofa 0.55 0.55 1 PMID:16223870 -3.1.1.1 5'-d-phenylalanyl-gemcitabine sus scrofa 1.1 1.1 1 PMID:16223870 -3.1.1.1 5'-d-valyl-gemcitabine sus scrofa 0.008 0.008 1 PMID:16223870 -3.1.1.1 5'-l-isoleucyl-gemcitabine sus scrofa 0.33 0.33 1 PMID:16223870 -3.1.1.1 5'-l-phenylalanine-floxuridine sus scrofa 0.62 0.62 1 PMID:16223870 -3.1.1.1 5'-l-phenylalanyl-bdcrb sus scrofa 8.0 8.0 1 PMID:16223870 -3.1.1.1 5'-l-phenylalanyl-gemcitabine sus scrofa 1.1 1.1 1 PMID:16223870 -3.1.1.1 5'-l-valyl-gemcitabine sus scrofa 0.008 0.008 1 PMID:16223870 -3.1.1.1 7-amino cephalosporanic acid agrobacterium tumefaciens 11.8 11.8 1 * -3.1.1.1 7-aminocephalosporanic acid uncultured bacterium 133.3 133.3 1 PMID:29453256 -3.1.1.1 7-ethyl-10-(4-(1-piperidino)-1-amino)carbonyloxycampothecin homo sapiens 0.004 0.00027 3 PMID:15100172 -3.1.1.1 7-ethyl-10-(4-(1-piperidino)-1-piperidino)carbonyloxycampothecin homo sapiens 0.017 8e-05 3 PMID:15100172 -3.1.1.1 7-ethyl-10-(4-n-(5-aminopentanoic acid)-1-piperidino)carbonyloxycampothecin homo sapiens 0.00041 0.00041 1 PMID:15100172 -3.1.1.1 7-ethyl-10-[4-(1-piperidino)-1-amino]carbonyloxycamptothecin altericroceibacterium indicum 0.59 0.59 1 PMID:36756200 -3.1.1.1 alpha-naphthyl acetate pseudomonas aeruginosa pao1 3000.0 3000.0 1 PMID:15717224 -3.1.1.1 alpha-naphthyl acetate tribolium castaneum 12.1 6.95 2 PMID:12213253 -3.1.1.1 alpha-naphthyl butyrate pseudomonas aeruginosa pao1 1600.0 1600.0 1 PMID:15717224 -3.1.1.1 benzyl acetate cereibacter sphaeroides 2.5 2.5 1 PMID:24832101 -3.1.1.1 benzyloxycarbonyl-d-tyr p-nitrophenyl ester equus caballus 0.57 0.57 1 PMID:237618 -3.1.1.1 benzyloxycarbonyl-d-tyr p-nitrophenyl ester sus scrofa 0.9 0.9 1 * -3.1.1.1 benzyloxycarbonyl-l-tyr p-nitrophenyl ester equus caballus 0.92 0.92 1 PMID:237618 -3.1.1.1 benzyloxycarbonyl-l-tyr p-nitrophenyl ester sus scrofa 24.0 24.0 1 * -3.1.1.1 bioresmethrin homo sapiens 0.034 0.034 1 PMID:16387282 -3.1.1.1 bioresmethrin oryctolagus cuniculus 0.11 0.11 1 PMID:16387282 -3.1.1.1 bisphenyl carbonate sus scrofa 1200.0 1200.0 1 PMID:7406498 -3.1.1.1 butyl 2-(4-[[5-(trifluoromethyl)pyridin-2-yl]oxy]phenoxy)propanoate aquamicrobium sp. fpb-1 4.46 4.46 1 PMID:28058522 -3.1.1.1 butyl 2-(4-[[5-(trifluoromethyl)pyridin-2-yl]oxy]phenoxy)propanoate brevundimonas sp. qpt-2 8.2 8.2 1 * -3.1.1.1 butyl 2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate aquamicrobium sp. fpb-1 4.17 4.17 1 PMID:28058522 -3.1.1.1 butyl 2-[4-(5-cyano-2-fluorophenoxy)phenoxy]propanoate brevundimonas sp. qpt-2 7.8 7.8 1 * -3.1.1.1 butyl butyrate equus caballus 11.1 11.1 1 PMID:3196030 -3.1.1.1 carboxyfluorescein diacetate pseudomonas aeruginosa 2800.0 2800.0 1 PMID:15717224 -3.1.1.1 carboxyfluorescein diacetate pseudomonas aeruginosa pao1 2800.0 2800.0 1 PMID:15717224 -3.1.1.1 cefazolin uncultured bacterium 0.000238 0.000238 1 PMID:21908637 -3.1.1.1 cis-permethrin klebsiella sp. 1.05 1.05 1 PMID:16448191 -3.1.1.1 cpt-11 altericroceibacterium indicum 0.668 0.668 1 PMID:36756200 -3.1.1.1 cyano(6-methoxy-2-naphthyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate mus musculus 0.11 0.11 1 PMID:15123619 -3.1.1.1 cyano(6-methoxy-2-naphthyl)methyl butanoate mus musculus 0.099 0.099 1 PMID:15123619 -3.1.1.1 cyano(6-methoxynaphthalen-2-yl)methyl (2s)-2-(4-chlorophenyl)-3-methylbutanoic acid mus musculus 0.067 0.067 1 PMID:15123619 -3.1.1.1 cypermethrin klebsiella sp. 0.288 0.288 1 PMID:16448191 -3.1.1.1 cypermethrin mus musculus 0.12 0.12 1 PMID:15123619 -3.1.1.1 d-glucose pentaacetate agrobacterium tumefaciens 4.22 4.22 1 * -3.1.1.1 d-tyr ethyl ester sus scrofa 71.0 71.0 1 * -3.1.1.1 d-xylose tetraacetate agrobacterium tumefaciens 12.2 12.2 1 * -3.1.1.1 deltamethrin klebsiella sp. 0.016 0.016 1 PMID:16448191 -3.1.1.1 ethyl 2-[4-[(5-chloro-3h-indol-2-yl)oxy]phenoxy]propanoate brevundimonas sp. qpt-2 11.4 11.4 1 * -3.1.1.1 ethyl 2-[4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy]propanoate aquamicrobium sp. fpb-1 5.28 5.145 2 PMID:28058522 -3.1.1.1 ethyl 2-[4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy]propanoate brevundimonas sp. qpt-2 10.1 10.1 1 * -3.1.1.1 ethyl 2-naphthyl acetate cereibacter sphaeroides 1.7 1.7 1 PMID:24832101 -3.1.1.1 ethyl 4-nitrophenyl acetate cereibacter sphaeroides 1.8 1.8 1 PMID:24832101 -3.1.1.1 ethyl 4-nitrophenyl methylphosphonate cereibacter sphaeroides 84.0 84.0 1 PMID:24832101 -3.1.1.1 ethyl butyrate equus caballus 135.0 135.0 1 PMID:237618 -3.1.1.1 ethyl butyrate galeocerdo cuvier 4.0 4.0 1 PMID:1276972 -3.1.1.1 ethyl butyrate gallus gallus 299.0 299.0 1 PMID:237618 -3.1.1.1 ethyl butyrate ovis aries 559.0 559.0 1 PMID:237618 -3.1.1.1 ethyl butyrate sus scrofa 551.0 551.0 1 PMID:237618 -3.1.1.1 ethyl butyrylacetate cereibacter sphaeroides 0.79 0.79 1 PMID:24832101 -3.1.1.1 ethylbutyrate equus caballus 4.4 4.4 1 PMID:3196030 -3.1.1.1 fenvalerate klebsiella sp. 0.103 0.103 1 PMID:16448191 -3.1.1.1 fluorescein diacetate pseudomonas aeruginosa 170.0 170.0 1 PMID:15717224 -3.1.1.1 fluorescein diacetate pseudomonas aeruginosa pao1 170.0 170.0 1 PMID:15717224 -3.1.1.1 geranyl acetate spodoptera exigua 0.5 0.5 1 PMID:26267057 -3.1.1.1 hexyl acetate spodoptera exigua 13.1 13.1 1 PMID:26267057 -3.1.1.1 indoxyl acetate cereibacter sphaeroides 2.3 2.3 1 PMID:24832101 -3.1.1.1 irinotecan sus scrofa 0.01 0.01 1 PMID:16223870 -3.1.1.1 isobutyl 4-nitrophenyl methylphosphonate cereibacter sphaeroides 8.0 8.0 1 PMID:24832101 -3.1.1.1 isopropyl 4-nitrophenyl methylphosphonate cereibacter sphaeroides 3.1 3.1 1 PMID:24832101 -3.1.1.1 l-phenylalanine butyl ester sus scrofa 0.08 0.08 1 PMID:16223870 -3.1.1.1 l-phenylalanine ethyl ester sus scrofa 63.6 63.6 1 PMID:16223870 -3.1.1.1 l-tyr ethyl ester sus scrofa 71.0 71.0 1 * -3.1.1.1 malathion klebsiella sp. 0.07 0.07 1 PMID:16448191 -3.1.1.1 malathion tribolium castaneum 13.0 7.9 2 PMID:12213253 -3.1.1.1 methyl 2-(4-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy]phenoxy)propanoate aquamicrobium sp. fpb-1 6.31 6.31 1 PMID:28058522 -3.1.1.1 methyl 2-(4-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy]phenoxy)propanoate brevundimonas sp. qpt-2 12.2 12.2 1 * -3.1.1.1 methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate aquamicrobium sp. fpb-1 5.92 5.92 1 PMID:28058522 -3.1.1.1 methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate brevundimonas sp. qpt-2 12.9 12.9 1 * -3.1.1.1 methyl butyrate equus caballus 286.0 286.0 1 PMID:237618 -3.1.1.1 methyl butyrate galeocerdo cuvier 10.0 10.0 1 PMID:1276972 -3.1.1.1 methyl butyrate gallus gallus 261.0 261.0 1 PMID:237618 -3.1.1.1 methyl butyrate ovis aries 454.0 454.0 1 PMID:237618 -3.1.1.1 methyl ferulate uncultured microorganism 1.03 1.03 1 PMID:34255285 -3.1.1.1 methyl paraoxon cereibacter sphaeroides 2.1 2.1 1 PMID:24832101 -3.1.1.1 n-acetyl l-phenylalanine ethyl ester sus scrofa 0.45 0.45 1 PMID:16223870 -3.1.1.1 n-acetyl-l-ala-1-naphthyl ester homo sapiens 651.0 651.0 1 PMID:3341748 -3.1.1.1 o-nitrophenyl butyrate galeocerdo cuvier 323.0 323.0 1 PMID:1276972 -3.1.1.1 o-nitrophenyl butyrate ovis aries 366.0 366.0 1 PMID:237618 -3.1.1.1 o-nitrophenyl butyrate sus scrofa 348.0 348.0 1 * -3.1.1.1 p-nitrophenyl acetate escherichia coli 18.5 18.5 1 PMID:12732651 -3.1.1.1 p-nitrophenyl acetate homo sapiens 70.0 43.5 2 PMID:16359636 -3.1.1.1 p-nitrophenyl acetate klebsiella sp. 81.0 81.0 1 PMID:16448191 -3.1.1.1 p-nitrophenyl acetate pseudomonas aeruginosa pao1 6400.0 6400.0 1 PMID:15717224 -3.1.1.1 p-nitrophenyl acetate thermotoga maritima 50.0 50.0 1 PMID:17106678 -3.1.1.1 p-nitrophenyl butanoate thermotoga maritima 14.0 14.0 1 PMID:17106678 -3.1.1.1 p-nitrophenyl butyrate escherichia coli 6.1 6.1 1 PMID:12732651 -3.1.1.1 p-nitrophenyl butyrate galeocerdo cuvier 401.0 401.0 1 PMID:1276972 -3.1.1.1 p-nitrophenyl butyrate gallus gallus 51.7 51.7 1 PMID:237618 -3.1.1.1 p-nitrophenyl butyrate pseudomonas aeruginosa pao1 1700.0 1700.0 1 PMID:15717224 -3.1.1.1 p-nitrophenyl butyrate sus scrofa 367.0 367.0 1 * -3.1.1.1 p-nitrophenyl caproate escherichia coli 4.0 4.0 1 PMID:12732651 -3.1.1.1 p-nitrophenyl caproate geobacillus stearothermophilus 39760.0 19899.0 2 PMID:15033540 -3.1.1.1 p-nitrophenyl caprylate thermotoga maritima 13.0 13.0 1 PMID:17106678 -3.1.1.1 p-nitrophenyl decanoate thermotoga maritima 10.8 10.8 1 PMID:17106678 -3.1.1.1 p-nitrophenyl hexanoate alicyclobacillus acidocaldarius 4320.0 2167.5 2 PMID:15581894 -3.1.1.1 p-nitrophenyl hexanoate saccharolobus solfataricus 2.47 2.47 1 PMID:15581894 -3.1.1.1 p-nitrophenyl laurate escherichia coli 1.5 1.5 1 PMID:12732651 -3.1.1.1 p-nitrophenyl myristate thermotoga maritima 4.9 4.9 1 PMID:17106678 -3.1.1.1 p-nitrophenyl propionate escherichia coli 13.1 13.1 1 PMID:12732651 -3.1.1.1 palmitoyl-coa escherichia coli 0.1 0.1 1 PMID:12732651 -3.1.1.1 paraoxon cereibacter sphaeroides 1.3 1.3 1 PMID:24832101 -3.1.1.1 pentyl acetate spodoptera exigua 59.0 59.0 1 PMID:26267057 -3.1.1.1 phenyl acetate bos taurus 300.0 300.0 1 * -3.1.1.1 phenyl acetate cereibacter sphaeroides 30.0 30.0 1 PMID:24832101 -3.1.1.1 phenyl acetate equus caballus 156.0 156.0 1 PMID:237618 -3.1.1.1 phenyl acetate paenarthrobacter nitroguajacolicus 550.0 550.0 1 PMID:17294326 -3.1.1.1 phenyl acetate sus scrofa 380.0 380.0 1 * -3.1.1.1 phenyl butyrate equus caballus 205.0 204.5 2 PMID:237618 -3.1.1.1 phenyl butyrate galeocerdo cuvier 661.0 661.0 1 PMID:1276972 -3.1.1.1 phenyl butyrate gallus gallus 476.0 476.0 1 PMID:237618 -3.1.1.1 phenyl butyrate ovis aries 565.0 565.0 1 PMID:237618 -3.1.1.1 phenyl butyrate sus scrofa 520.0 519.5 2 PMID:237618 -3.1.1.1 phenyl formate equus caballus 3100.0 3100.0 1 PMID:237618 -3.1.1.1 phenyl formate sus scrofa 660.0 660.0 1 * -3.1.1.1 phenyl pentanoate equus caballus 263.0 263.0 1 PMID:237618 -3.1.1.1 phenyl pentanoate sus scrofa 860.0 860.0 1 * -3.1.1.1 phenyl pivalate equus caballus 9.7 9.7 1 PMID:237618 -3.1.1.1 phenyl trimethyl acetate bos taurus 6.5 6.5 1 * -3.1.1.1 phenylbutyrate equus caballus 3.5 3.5 1 PMID:3196030 -3.1.1.1 phenylthioacetate equus caballus 5.0 5.0 1 PMID:3196030 -3.1.1.1 phenylthiobutyrate equus caballus 4.4 4.4 1 PMID:3196030 -3.1.1.1 phenylthioisobutyrate equus caballus 3.7 3.7 1 PMID:3196030 -3.1.1.1 phenylthiopentanoate equus caballus 4.6 4.6 1 PMID:3196030 -3.1.1.1 phenylthiopropionate equus caballus 8.9 8.9 1 PMID:3196030 -3.1.1.1 retinyl palmitate rattus norvegicus 0.0075 0.004 5 PMID:12230550 -3.1.1.1 trans-permethrin bacillus subtilis 2.9 2.9 1 PMID:18163883 -3.1.1.1 trans-permethrin klebsiella sp. 1.14 1.14 1 PMID:16448191 -3.1.1.1 triacetin alicyclobacillus acidocaldarius 945.0 945.0 1 PMID:16325466 -3.1.1.1 triacetin archaeoglobus fulgidus 40.0 40.0 1 PMID:16325466 -3.1.1.1 triacetin ferroplasma acidiphilum 47.0 47.0 1 PMID:16478448 -3.1.1.1 tributyrin alicyclobacillus acidocaldarius 1290.0 1290.0 1 PMID:16325466 -3.1.1.1 tributyrin archaeoglobus fulgidus 95.0 95.0 1 PMID:16325466 -3.1.1.1 tributyrin ferroplasma acidiphilum 23.0 23.0 1 PMID:16478448 -3.1.1.1 tributyrin homo sapiens 18.0 18.0 1 PMID:16325466 -3.1.1.1 tripropionin alicyclobacillus acidocaldarius 835.0 835.0 1 PMID:16325466 -3.1.1.1 tripropionin archaeoglobus fulgidus 110.0 110.0 1 PMID:16325466 -3.1.1.1 tripropionin ferroplasma acidiphilum 44.0 44.0 1 PMID:16478448 -3.1.1.1 tripropionin homo sapiens 7.0 7.0 1 PMID:16325466 -3.1.1.1 vinyl acetate alicyclobacillus acidocaldarius 110.0 110.0 1 PMID:16325466 -3.1.1.1 vinyl acetate archaeoglobus fulgidus 50.0 50.0 1 PMID:16325466 -3.1.1.1 vinyl acetate homo sapiens 140.0 140.0 1 PMID:16325466 -3.1.1.1 vinyl butanoate alicyclobacillus acidocaldarius 1930.0 1930.0 1 PMID:16325466 -3.1.1.1 vinyl butanoate archaeoglobus fulgidus 210.0 210.0 1 PMID:16325466 -3.1.1.1 vinyl butanoate homo sapiens 210.0 210.0 1 PMID:16325466 -3.1.1.1 vinyl laurate homo sapiens 31.0 31.0 1 PMID:16325466 -3.1.1.1 vinyl propionate alicyclobacillus acidocaldarius 980.0 980.0 1 PMID:16325466 -3.1.1.1 vinyl propionate archaeoglobus fulgidus 200.0 200.0 1 PMID:16325466 -3.1.1.1 vinyl propionate homo sapiens 105.0 105.0 1 PMID:16325466 -3.1.1.10 atropine oryctolagus cuniculus 68.0 68.0 1 PMID:4435736 -3.1.1.10 butyrylcholine oryctolagus cuniculus 1930.0 1930.0 1 PMID:4435736 -3.1.1.101 4-nitrophenyl acetate bacterium hr29 130.9 130.9 1 PMID:33375975 -3.1.1.101 4-nitrophenyl acetate marinactinospora thermotolerans 4.47 4.47 1 PMID:35557867 -3.1.1.101 4-nitrophenyl acetate piscinibacter sakaiensis 75.0 27.0 3 PMID:33375975;PMID:37555384 -3.1.1.101 4-nitrophenyl butanoate bacterium hr29 53.9 53.9 1 PMID:33375975 -3.1.1.101 4-nitrophenyl butanoate marinactinospora thermotolerans 14.1 14.1 1 PMID:35557867 -3.1.1.101 4-nitrophenyl butanoate piscinibacter sakaiensis 24.1 24.1 1 PMID:33375975 -3.1.1.101 4-nitrophenyl butanoate thermomonospora curvata 12.4 7.35 2 PMID:254050803 -3.1.1.101 4-nitrophenyl decanoate marinactinospora thermotolerans 69.85 69.85 1 PMID:35557867 -3.1.1.101 4-nitrophenyl dodecanoate bacterium hr29 32.3 32.3 1 PMID:33375975 -3.1.1.101 4-nitrophenyl dodecanoate marinactinospora thermotolerans 30.52 30.52 1 PMID:35557867 -3.1.1.101 4-nitrophenyl hexadecanoate marinactinospora thermotolerans 4.79 4.79 1 PMID:35557867 -3.1.1.101 4-nitrophenyl hexanoate bacterium hr29 47.7 47.7 1 PMID:33375975 -3.1.1.101 4-nitrophenyl hexanoate marinactinospora thermotolerans 41.72 41.72 1 PMID:35557867 -3.1.1.101 4-nitrophenyl hexanoate piscinibacter sakaiensis 12.7 12.7 1 PMID:33375975 -3.1.1.101 4-nitrophenyl octadecanoate marinactinospora thermotolerans 14.31 14.31 1 PMID:35557867 -3.1.1.101 4-nitrophenyl octanoate bacterium hr29 39.8 39.8 1 PMID:33375975 -3.1.1.101 4-nitrophenyl octanoate marinactinospora thermotolerans 79.39 79.39 1 PMID:35557867 -3.1.1.101 4-nitrophenyl octanoate piscinibacter sakaiensis 3.2 3.2 1 PMID:33375975 -3.1.1.101 4-nitrophenyl tetradecanoate bacterium hr29 25.9 25.9 1 PMID:33375975 -3.1.1.101 4-nitrophenyl tetradecanoate marinactinospora thermotolerans 9.87 9.87 1 PMID:35557867 -3.1.1.101 bis (2-hydroxyethyl) terephthalic acid piscinibacter sakaiensis 5.95 5.95 1 PMID:35557867 -3.1.1.101 bis(2-hydroxyethyl) terephthalic acid marinactinospora thermotolerans 3.07 3.07 1 PMID:35557867 -3.1.1.101 bis(2-hydroxyethyl)terephthalate bacterium hr29 7.3 7.3 1 PMID:33375975 -3.1.1.101 bis(2-hydroxyethyl)terephthalate piscinibacter sakaiensis 40.3 40.3 1 PMID:33375975 -3.1.1.101 bis-((2-hydroxyethyl)terephthalic acid) marinactinospora thermotolerans 4.27 4.27 1 PMID:35557867 -3.1.1.101 mono (2-hydroxyethyl) terephthalic acid piscinibacter sakaiensis 0.14 0.14 1 PMID:35557867 -3.1.1.101 mono(2-hydroxyethyl) terephthalic acid marinactinospora thermotolerans 0.75 0.75 1 PMID:35557867 -3.1.1.101 mono-(2-hydroxyethyl)terephthalic acid marinactinospora thermotolerans 0.13 0.13 1 PMID:35557867 -3.1.1.102 4-[(2-hydroxyethoxy)carbonyl]benzoate comamonas thiooxydans 9.5 9.5 1 PMID:32989159 -3.1.1.102 4-[(2-hydroxyethoxy)carbonyl]benzoate hydrogenophaga sp. pml113 3.8 3.8 1 PMID:32989159 -3.1.1.102 4-[(2-hydroxyethoxy)carbonyl]benzoate piscinibacter sakaiensis 27.6 27.6 1 PMID:32989159 -3.1.1.102 bis(2-hydroxyethyl) terephthalate piscinibacter sakaiensis 0.0255 0.0255 1 * -3.1.1.102 bis(2-hydroxyethyl) terephthalic acid thermobifida fusca 26.8 26.8 1 * -3.1.1.102 ethylene terephthalate piscinibacter sakaiensis 31.0 31.0 1 PMID:26965627 -3.1.1.102 ethylene terephthalate thermobifida fusca 0.31 0.31 1 * -3.1.1.104 d-xylono-1,4-lactone 5-phosphate mycoplasmopsis agalactiae 51.0 51.0 1 PMID:24955762 -3.1.1.104 d-xylono-1,4-lactone 5-phosphate mycoplasmopsis synoviae 23.4 23.4 1 PMID:24955762 -3.1.1.104 l-arabino-1,4-lactone 5-phosphate mycoplasmopsis agalactiae 8.7 8.7 1 PMID:24955762 -3.1.1.104 l-arabino-1,4-lactone 5-phosphate mycoplasmopsis synoviae 6.7 6.7 1 PMID:24955762 -3.1.1.106 2''-o-acetyl-adp-d-ribose escherichia coli 1.31 1.31 1 PMID:26481419 -3.1.1.106 2''-o-acetyl-adp-d-ribose homo sapiens 0.72 0.45999999999999996 2 PMID:25051211 -3.1.1.106 o-acetyl-adp-d-ribose escherichia coli 0.48 0.48 1 PMID:21257746 -3.1.1.106 o-acetyl-adp-d-ribose homo sapiens 0.198 0.159 2 PMID:21257746 -3.1.1.106 o-acetyl-adp-d-ribose staphylococcus aureus 2.77 2.77 1 PMID:21257746 -3.1.1.107 diglucosyl-enterobactin escherichia coli 5.33 5.33 1 PMID:16076215 -3.1.1.107 enterobactin escherichia coli 6.25 6.25 1 PMID:16076215 -3.1.1.107 ferric diglucosyl-enterobactin escherichia coli 0.04 0.04 1 PMID:16076215 -3.1.1.107 ferric enterobactin escherichia coli 0.05 0.05 1 PMID:16076215 -3.1.1.107 ferric monoglucosyl-enterobactin escherichia coli 0.05 0.05 1 PMID:16076215 -3.1.1.107 ferric triglucosyl-enterobactin escherichia coli 0.13 0.13 1 PMID:16076215 -3.1.1.107 monoglucosyl-enterobactin escherichia coli 7.17 7.17 1 PMID:16076215 -3.1.1.107 triglucosyl-enterobactin escherichia coli 7.5 7.5 1 PMID:16076215 -3.1.1.108 4-nitrophenyl acetate geobacillus thermodenitrificans 6.8 6.8 1 PMID:31053933 -3.1.1.108 4-nitrophenyl butyrate geobacillus thermodenitrificans 3.03 3.03 1 PMID:31053933 -3.1.1.108 4-nitrophenyl caprylate geobacillus thermodenitrificans 1.24 1.24 1 PMID:31053933 -3.1.1.108 diglucosyl-enterobactin escherichia coli 1.3 1.3 1 PMID:16076215 -3.1.1.108 enterobactin escherichia coli 8.67 8.67 1 PMID:16076215 -3.1.1.108 iron(iii)-enterobactin escherichia coli 0.15 0.15 1 PMID:16076215 -3.1.1.108 iron(iii)-monoglucosyl-enterobactin escherichia coli 0.023 0.023 1 PMID:16076215 -3.1.1.108 monoglucosyl-enterobactin escherichia coli 14.17 14.17 1 PMID:16076215 -3.1.1.109 [diglucosyl-enterobactin] complex escherichia coli 108.33 108.33 1 PMID:16076215 -3.1.1.109 [monoglucosyl-enterobactin] complex escherichia coli 62.0 62.0 1 PMID:16076215 -3.1.1.109 [triglucosyl-enterobactin] complex escherichia coli 74.33 74.33 1 PMID:16076215 -3.1.1.109 enterobactin escherichia coli 17.67 17.67 1 PMID:16076215 -3.1.1.109 iron(iii)-[diglucosyl-enterobactin] complex escherichia coli 0.53 0.53 1 PMID:16076215 -3.1.1.109 iron(iii)-[monoglucosyl-enterobactin] complex escherichia coli 0.77 0.77 1 PMID:16076215 -3.1.1.109 iron(iii)-[triglucosyl-enterobactin] complex escherichia coli 1.4 1.4 1 PMID:16076215 -3.1.1.109 iron(iii)-enterobactin escherichia coli 1.23 1.23 1 PMID:16076215 -3.1.1.11 6-o-methyl galacturonic acid bacteroides thetaiotaomicron 0.2 0.15000000000000002 2 PMID:33097594 -3.1.1.11 6-o-methyl glucuronic acid bacteroides thetaiotaomicron 0.2 0.15000000000000002 2 PMID:33097594 -3.1.1.11 apple pectin bacteroides thetaiotaomicron 0.4 0.35 2 PMID:33097594 -3.1.1.11 apple rhamnogalacturonan-ii bacteroides thetaiotaomicron 0.6 0.5 2 PMID:33097594 -3.1.1.11 citrus pectin penicillium oxalicum 47.6 47.6 1 PMID:24584459 -3.1.1.11 glca-(1->4)-beta-(2-o-me-xyl-alpha1,3)-fuc-(1->4)-alpha-(gala-(1->3)-beta)-rha-(1->3)-alpha-api-(1->2)-beta-(araf-(1->3)-alpha)-(gala-(1->4)-alpha)-gala bacteroides thetaiotaomicron 0.2 0.2 2 PMID:33097594 -3.1.1.11 pectin acetivibrio thermocellus 3.77 3.06 5 PMID:28332030 -3.1.1.11 pectin aspergillus niger 22.33 22.33 1 PMID:30042002 -3.1.1.11 pectin dickeya chrysanthemi 450.0 450.0 1 PMID:17717531 -3.1.1.11 rha-(1->3)-alpha-api-(1->2)-beta-araf-(1->3)-alpha-(6-o-me)-gala-(1->4-alpha)-gala bacteroides thetaiotaomicron 0.3 0.25 2 PMID:33097594 -3.1.1.113 4-nitrophenyl acetate pseudomonas putida 64.0 64.0 1 * -3.1.1.113 alpha-naphthyl acetate pseudomonas putida 29.0 29.0 1 * -3.1.1.117 1-(4-hydroxy-3-methoxyphenyl)-1-(alpha-d-glucuronate)-2-(2-methoxyphenoxy)-3-propanol podospora anserina 7.8 7.8 1 PMID:26404219 -3.1.1.117 1-(4-hydroxy-3-methoxyphenyl)-1-(alpha-d-glucuronate)-2-(2-methoxyphenoxy)-3-propanol thermothelomyces thermophilus 3.5 3.5 1 PMID:26404219 -3.1.1.117 3-(4-hydroxyphenyl)-1-propyl d-glucopyranosyluronate podospora anserina 0.19 0.19 1 PMID:24531271 -3.1.1.117 3-(4-hydroxyphenyl)prop-1-yl 4-o-methyl-d-glucopyranuronate podospora anserina 0.19 0.19 1 PMID:24531271 -3.1.1.117 3-(4-methoxyphenyl) propyl methyl 4-o-methyl-alpha-d-glucopyranosiduronate aspergillus fumigatus 67.1 67.1 1 PMID:29332217 -3.1.1.117 3-(4-methoxyphenyl)propyl d-glucopyranosyluronate schizophyllum commune 0.2 0.2 1 PMID:17440709 -3.1.1.117 3-(4-methoxyphenyl)propyl methyl 4-o-methyl-alpha-d-glucopyranosiduronate schizophyllum commune 7.8 7.8 1 PMID:17440709 -3.1.1.117 3-phenyl-1-propyl d-glucopyranosyluronate podospora anserina 0.78 0.78 1 PMID:24531271 -3.1.1.117 3-phenyl-1-propyl d-glucopyranosyluronate thermothelomyces thermophilus 2.77 2.77 1 PMID:24531271 -3.1.1.117 3-phenylprop-1-yl 4-o-methyl-d-glucopyranuronate podospora anserina 0.77 0.77 1 PMID:24531271 -3.1.1.117 3-phenylprop-1-yl 4-o-methyl-d-glucopyranuronate thermothelomyces thermophilus 2.77 2.77 1 PMID:24531271 -3.1.1.117 4-nitrophenyl 2-o-(methyl 4-o-methyl-alpha-d-glucopyranosyluronate)-beta-d-xylopyranoside schizophyllum commune 3.2 3.2 1 PMID:16876163;PMID:17440709 -3.1.1.117 4-nitrophenyl 2-o-(methyl-4-o-methyl-alpha-d-glucopyranosyluronate)-beta-d-xylopyranoside thermothelomyces thermophilus 0.808 0.808 1 PMID:19459957 -3.1.1.117 4-nitrophenyl 2-o-(methyl-4-o-methyl-alpha-d-glucopyranosyluronate)-beta-d-xylopyranoside trichoderma reesei 4.5 4.5 1 PMID:17678650 -3.1.1.117 4-o-methyl-glucuronic acid gamma-linked to a lignin dimer cerrena unicolor 285.0 285.0 1 PMID:26712478 -3.1.1.117 4-o-methyl-glucuronic acid gamma-linked to a lignin dimer schizophyllum commune 125.0 125.0 1 PMID:26712478 -3.1.1.117 allyl-d-glucuronate teredinibacter turnerae 200.0 200.0 1 PMID:30814248 -3.1.1.117 benzyl d-glucuronate aspergillus fumigatus 23.8 23.8 1 PMID:29332217 -3.1.1.117 benzyl d-glucuronate opitutus terrae 19.0 19.0 1 PMID:35304453 -3.1.1.117 benzyl glucuronic acid gelatoporia subvermispora 23.6 23.6 1 PMID:30232535 -3.1.1.117 benzyl glucuronic acid phanerodontia chrysosporium 1.45 1.45 1 PMID:28429057 -3.1.1.117 benzyl glucuronic acid pleurotus eryngii 104.6 104.6 1 PMID:30232535 -3.1.1.117 benzyl glucuronic acid sodiomyces alcalophilus 0.79 0.79 1 PMID:28429057 -3.1.1.117 benzyl glucuronic acid wolfiporia cocos 0.37 0.37 1 PMID:28429057 -3.1.1.117 benzyl methyl 4-o-methyl-alpha-d-glucopyranosiduronate aspergillus fumigatus 66.4 66.4 1 PMID:29332217 -3.1.1.117 benzyl methyl alpha-d-glucopyranosiduronate aspergillus fumigatus 42.7 42.7 1 PMID:29332217 -3.1.1.117 benzyl-d-glucuronate caldicellulosiruptor acetigenus 0.0565 0.0381 2 PMID:32308737 -3.1.1.117 benzyl-d-glucuronate opitutus terrae 16.6 16.6 1 PMID:31740581 -3.1.1.117 benzyl-d-glucuronate phanerodontia chrysosporium 0.37 0.37 1 PMID:28429057 -3.1.1.117 benzyl-d-glucuronate sodiomyces alcalophilus 0.79 0.79 1 PMID:28429057 -3.1.1.117 benzyl-d-glucuronate teredinibacter turnerae 132.0 132.0 1 PMID:30814248 -3.1.1.117 benzyl-d-glucuronate wolfiporia cocos 1.45 1.45 1 PMID:28429057 -3.1.1.117 cinnamyl 4-o-methyl-d-glucopyranuronate podospora anserina 5.25 5.25 1 PMID:24531271 -3.1.1.117 cinnamyl 4-o-methyl-d-glucopyranuronate thermothelomyces thermophilus 1.93 1.93 1 PMID:24531271 -3.1.1.117 lignin-rich pellet armillaria fuscipes 1.82 1.82 1 PMID:30949809 -3.1.1.117 lignin-rich pellet cerrena unicolor 2.58 2.58 1 PMID:30949809 -3.1.1.117 lignin-rich pellet punctularia strigosozonata 2.87 2.87 1 PMID:30949809 -3.1.1.117 lignin-rich pellet thermothielavioides terrestris 0.0886 0.0886 1 PMID:30949809 -3.1.1.117 methyl-d-galacturonate opitutus terrae 28.8 28.8 1 PMID:31740581 -3.1.1.117 methyl-d-galacturonate teredinibacter turnerae 0.012 0.012 1 PMID:30814248 -3.1.1.117 methyl-d-glucuronate opitutus terrae 19.0 19.0 1 PMID:31740581 -3.1.1.117 trans-3-phenyl-2-propen-1-yl d-glucopyranosyluronate podospora anserina 5.26 5.26 1 PMID:24531271 -3.1.1.117 trans-3-phenyl-2-propen-1-yl d-glucopyranosyluronate thermothelomyces thermophilus 1.93 1.93 1 PMID:24531271 -3.1.1.120 4-deoxy-l-fucono-1,5-lactone burkholderia multivorans 994.0 994.0 1 PMID:23214453 -3.1.1.120 d-arabino-1,4-lactone burkholderia multivorans 59.0 30.5 2 PMID:23214453 -3.1.1.120 l-fucono-1,4-lactone burkholderia multivorans 140.0 72.0 2 PMID:23214453 -3.1.1.120 l-galactono-1,4-lactone burkholderia multivorans 32.0 19.0 2 PMID:23214453 -3.1.1.120 l-xylono-1,4-lactone burkholderia multivorans 14.0 14.0 1 PMID:23214453 -3.1.1.122 carbendazim nocardioides sp. sg-4g 2.83 2.83 1 PMID:20228105 -3.1.1.124 punicalagin aspergillus niger 1260000.0 1260000.0 1 PMID:28183264 -3.1.1.13 4-nitrophenyl acetate sus scrofa 1.07 1.07 1 PMID:12831 -3.1.1.13 4-nitrophenyl butyrate limtongozyma cylindracea 63330.0 60000.0 5 PMID:12007617 -3.1.1.13 4-nitrophenyl butyrate ophiostoma piceae 44.0 44.0 1 PMID:12479402 -3.1.1.13 4-nitrophenyl butyrate sus scrofa 650.0 525.0 2 PMID:12007617 -3.1.1.13 4-nitrophenyl laurate streptomyces avermitilis 2.56 2.56 1 PMID:17161031 -3.1.1.13 4-nitrophenyl laurate streptomyces griseus 3.43 3.43 1 PMID:17161031 -3.1.1.13 4-nitrophenyl myristate streptomyces avermitilis 2.52 2.52 1 PMID:17161031 -3.1.1.13 4-nitrophenyl myristate streptomyces griseus 3.86 3.86 1 PMID:17161031 -3.1.1.13 4-nitrophenyl palmitate ophiostoma piceae 74.0 74.0 1 PMID:12479402 -3.1.1.13 4-nitrophenyl palmitate streptomyces avermitilis 1.44 1.44 1 PMID:17161031 -3.1.1.13 4-nitrophenyl palmitate streptomyces griseus 1.73 1.73 1 PMID:17161031 -3.1.1.13 cholesteryl acetate streptomyces sp. 110.0 110.0 1 PMID:16503286 -3.1.1.13 cholesteryl butyrate ophiostoma piceae 47.0 47.0 1 PMID:12479402 -3.1.1.13 cholesteryl linoleate ophiostoma piceae 150.0 150.0 1 PMID:12479402 -3.1.1.13 cholesteryl linoleate streptomyces avermitilis 24.7 24.7 1 PMID:17161031 -3.1.1.13 cholesteryl linoleate streptomyces griseus 25.6 25.6 1 PMID:17161031 -3.1.1.13 cholesteryl linoleate streptomyces sp. 31.2 31.2 1 PMID:16503286 -3.1.1.13 cholesteryl myristate streptomyces avermitilis 12.4 12.4 1 PMID:17161031 -3.1.1.13 cholesteryl myristate streptomyces griseus 13.3 13.3 1 PMID:17161031 -3.1.1.13 cholesteryl myristate streptomyces sp. 23.5 23.5 1 PMID:16503286 -3.1.1.13 cholesteryl oleate ophiostoma piceae 138.0 138.0 1 PMID:12479402 -3.1.1.13 cholesteryl oleate sus scrofa 0.35 0.35 1 PMID:12831 -3.1.1.13 cholesteryl palmitate ophiostoma piceae 67.0 67.0 1 PMID:12479402 -3.1.1.13 cholesteryl palmitate streptomyces avermitilis 15.7 15.7 1 PMID:17161031 -3.1.1.13 cholesteryl palmitate streptomyces sp. 96.7 96.7 1 PMID:16503286 -3.1.1.13 cholesteryl stearate ophiostoma piceae 71.0 71.0 1 PMID:12479402 -3.1.1.13 cholesteryl stearate streptomyces griseus 23.3 23.3 1 PMID:17161031 -3.1.1.13 cholesteryl stearate streptomyces sp. 70.8 70.8 1 PMID:16503286 -3.1.1.13 p-nitrophenyl laurate streptomyces sp. 1.4 1.4 1 PMID:16503286 -3.1.1.13 p-nitrophenyl myristate streptomyces sp. 4.5 4.5 1 PMID:16503286 -3.1.1.13 p-nitrophenyl palmitate streptomyces sp. 2.9 2.9 1 PMID:16503286 -3.1.1.13 tributyrin ophiostoma piceae 179.0 179.0 1 PMID:12479402 -3.1.1.13 triolein ophiostoma piceae 290.0 290.0 1 PMID:12479402 -3.1.1.14 4-nitrophenyl decanoate triticum aestivum 9.43 8.74 2 PMID:16643837 -3.1.1.14 bacteriochlorophyll a chlamydomonas reinhardtii 212.2 212.2 1 PMID:26478543 -3.1.1.14 bacteriochlorophyll a crocosphaera subtropica atcc 51142 726.33 726.33 1 PMID:25828734 -3.1.1.14 bacteriochlorophyll a oxynema acuminatum 0.0107 0.0107 1 PMID:33430874 -3.1.1.14 bacteriochlorophyll a triticum aestivum 7.5 7.5 1 PMID:36731794 -3.1.1.14 chlorophyll triticum aestivum 566.0 566.0 1 PMID:15913540 -3.1.1.14 chlorophyll a brassica oleracea 0.072 0.0372 2 PMID:20681655 -3.1.1.14 chlorophyll a chlamydomonas reinhardtii 559.55 559.55 1 PMID:26478543 -3.1.1.14 chlorophyll a crocosphaera subtropica atcc 51142 251.08 251.08 1 PMID:25828734 -3.1.1.14 chlorophyll a oxynema acuminatum 0.00065 0.00065 1 PMID:33430874 -3.1.1.14 chlorophyll a solanum lycopersicum 0.0234 0.0024 3 PMID:36233017 -3.1.1.14 chlorophyll a triticum aestivum 12.0 8.55 4 PMID:36731794 -3.1.1.14 chlorophyll b brassica oleracea 0.072 0.037849999999999995 2 PMID:20681655 -3.1.1.14 chlorophyll b chlamydomonas reinhardtii 232.8 232.8 1 PMID:26478543 -3.1.1.14 chlorophyll b crocosphaera subtropica atcc 51142 310.36 310.36 1 PMID:25828734 -3.1.1.14 chlorophyll b oxynema acuminatum 0.00142 0.00142 1 PMID:33430874 -3.1.1.14 chlorophyll b solanum lycopersicum 0.0295 0.0027 3 PMID:36233017 -3.1.1.14 chlorophyll b triticum aestivum 6.0 6.0 1 PMID:36731794 -3.1.1.14 p-nitrophenyl butyrate triticum aestivum 10.3 10.3 1 PMID:15913540 -3.1.1.14 p-nitrophenyl decanoate triticum aestivum 0.52 0.52 1 PMID:15913540 -3.1.1.14 p-nitrophenyl palmitate triticum aestivum 0.2 0.2 1 PMID:15913540 -3.1.1.14 pheophorbide a methyl ester brassica oleracea 0.259 0.13145 2 PMID:20681655 -3.1.1.14 pheophytin a oxynema acuminatum 0.0019 0.0019 1 PMID:33430874 -3.1.1.14 pheophytin a solanum lycopersicum 0.0032 0.0032 1 PMID:36233017 -3.1.1.14 pheophytin a triticum aestivum 3.1 3.1 1 PMID:36731794 -3.1.1.17 d-glucono-1,5-lactone euglena gracilis 192.0 192.0 1 PMID:18782759 -3.1.1.17 d-gulono-1,5-lactone euglena gracilis 160.0 160.0 1 PMID:18782759 -3.1.1.17 l-galactonic acid euglena gracilis 615.0 615.0 1 PMID:18782759 -3.1.1.17 l-galactono-1,4-lactone euglena gracilis 450.0 450.0 1 PMID:18782759 -3.1.1.17 l-gulonic acid euglena gracilis 1503.0 1503.0 1 PMID:18782759 -3.1.1.17 l-gulono-1,4-lactone euglena gracilis 1040.0 1040.0 1 PMID:18782759 -3.1.1.2 1-naphthyl acetate gluconobacter oxydans 4.7 4.7 1 PMID:26443058 -3.1.1.2 1-naphthyl butyrate gluconobacter oxydans 9.8 9.8 1 PMID:26443058 -3.1.1.2 1-phenylvinyl acetate homo sapiens 1.0 1.0 1 PMID:15835926 -3.1.1.2 2,2,2-trifluoroethyl acetate homo sapiens 4.0 4.0 1 PMID:15835926 -3.1.1.2 2,2-difluoroethyl acetate homo sapiens 0.82 0.82 1 PMID:15835926 -3.1.1.2 2,3-difluorophenyl acetate homo sapiens 403.0 403.0 1 PMID:15835926 -3.1.1.2 2,4-difluorophenyl acetate homo sapiens 334.0 334.0 1 PMID:15835926 -3.1.1.2 2,6-difluorophenyl acetate homo sapiens 145.0 145.0 1 PMID:15835926 -3.1.1.2 2-fluoroethyl acetate homo sapiens 0.5 0.5 1 PMID:15835926 -3.1.1.2 2-fluorophenyl acetate homo sapiens 431.0 431.0 1 PMID:15835926 -3.1.1.2 2-naphthyl acetate gluconobacter oxydans 55.2 35.2 2 PMID:23003572;PMID:26443058 -3.1.1.2 2-naphthyl acetate homo sapiens 26.25 10.4 4 PMID:14695884 -3.1.1.2 2-naphthyl acetate mus musculus 2.12 2.12 1 PMID:14695884 -3.1.1.2 2-naphthyl acetate oryctolagus cuniculus 0.66 0.66 1 PMID:14695884 -3.1.1.2 2-naphthyl butanoate gluconobacter oxydans 7.0 7.0 1 PMID:23003572 -3.1.1.2 2-naphthyl butyrate gluconobacter oxydans 22.7 22.7 1 PMID:26443058 -3.1.1.2 3,4-dimethyl phenyl acetate homo sapiens 51.0 51.0 1 PMID:15835926 -3.1.1.2 3-cyanophenyl acetate homo sapiens 125.0 125.0 1 PMID:15835926 -3.1.1.2 3-fluorophenyl acetate homo sapiens 571.0 571.0 1 PMID:15835926 -3.1.1.2 3-naphthyl acetate gluconobacter oxydans 99.0 99.0 1 PMID:23003572 -3.1.1.2 3-naphthyl butanoate gluconobacter oxydans 16.4 16.4 1 PMID:23003572 -3.1.1.2 3-nitrophenyl acetate homo sapiens 59.0 59.0 1 PMID:15835926 -3.1.1.2 4-acetoxy methyl benzoate homo sapiens 14.0 14.0 1 PMID:15835926 -3.1.1.2 4-acetoxyacetophenone homo sapiens 13.0 13.0 1 PMID:15835926 -3.1.1.2 4-acetoxybenzaldehyde homo sapiens 26.0 26.0 1 PMID:18951406 -3.1.1.2 4-chlorophenyl acetate homo sapiens 117.0 117.0 1 PMID:15835926 -3.1.1.2 4-cyanophenyl acetate homo sapiens 23.0 23.0 1 PMID:15835926 -3.1.1.2 4-diethyl phosphate methyl benzoate homo sapiens 0.244 0.244 1 PMID:15835926 -3.1.1.2 4-nitrophenyl acetate gluconobacter oxydans 185.0 105.35 2 PMID:23003572;PMID:26443058 -3.1.1.2 4-nitrophenyl acetate homo sapiens 2500.0 1300.0 3 PMID:15835926;PMID:21382471 -3.1.1.2 4-nitrophenyl acetate lacticaseibacillus rhamnosus 37.6 37.35 2 PMID:34881159 -3.1.1.2 4-nitrophenyl acetate oryctolagus cuniculus 2500.0 2500.0 1 PMID:21382471 -3.1.1.2 4-nitrophenyl acetate saccharolobus islandicus 0.2 0.2 1 PMID:23071703 -3.1.1.2 4-nitrophenyl acetate sulfolobus acidocaldarius 0.13 0.13 1 PMID:24894602 -3.1.1.2 4-nitrophenyl acetate vulcanisaeta moutnovskia 1.66 1.66 1 PMID:24858677 -3.1.1.2 4-nitrophenyl butanoate gluconobacter oxydans 97.2 97.2 1 PMID:23003572 -3.1.1.2 4-nitrophenyl butyrate gluconobacter oxydans 17.6 17.6 1 PMID:26443058 -3.1.1.2 4-nitrophenyl butyrate lacticaseibacillus rhamnosus 32.3 32.15 2 PMID:34881159 -3.1.1.2 4-nitrophenyl butyrate saccharolobus solfataricus 285.0 285.0 1 PMID:18931117 -3.1.1.2 4-nitrophenyl caprate lacticaseibacillus rhamnosus 17.4 16.0 2 PMID:34881159 -3.1.1.2 4-nitrophenyl caprate saccharolobus solfataricus 341.0 341.0 1 PMID:18931117 -3.1.1.2 4-nitrophenyl caproate lacticaseibacillus rhamnosus 53.2 51.0 2 PMID:34881159 -3.1.1.2 4-nitrophenyl caproate saccharolobus solfataricus 467.0 467.0 1 PMID:18931117 -3.1.1.2 4-nitrophenyl caprylate lacticaseibacillus rhamnosus 62.7 53.25 2 PMID:34881159 -3.1.1.2 4-nitrophenyl caprylate saccharolobus solfataricus 410.0 410.0 1 PMID:18931117 -3.1.1.2 4-nitrophenyl laurate lacticaseibacillus rhamnosus 2.0 1.9 2 PMID:34881159 -3.1.1.2 4-nitrophenyl laurate saccharolobus solfataricus 264.0 264.0 1 PMID:18931117 -3.1.1.2 4-nitrophenyl palmitate saccharolobus solfataricus 265.0 265.0 1 PMID:18931117 -3.1.1.2 4-nitrophenyl phosphate saccharolobus solfataricus 269.0 269.0 1 PMID:18931117 -3.1.1.2 4-nitrophenyl propionate homo sapiens 1.27 1.27 1 PMID:32382056 -3.1.1.2 7-aminocephalosporanic acid gluconobacter oxydans 69.5 65.4 2 PMID:26443058 -3.1.1.2 alpha-naphthyl acetate saccharolobus solfataricus 450.0 450.0 1 PMID:18931117 -3.1.1.2 benzyl acetate homo sapiens 0.02 0.0104 2 PMID:15835926 -3.1.1.2 butyl acetate homo sapiens 0.27 0.27 1 PMID:15835926 -3.1.1.2 cephalosporin c gluconobacter oxydans 42.7 31.755000000000003 2 PMID:26443058 -3.1.1.2 ethyl acetate homo sapiens 0.242 0.242 1 PMID:15835926 -3.1.1.2 naphthalen-2-yl acetate homo sapiens 18.0 18.0 1 PMID:16407305 -3.1.1.2 p-tolyl acetate homo sapiens 68.0 68.0 1 PMID:15835926 -3.1.1.2 phenyl acetate gluconobacter oxydans 231.0 166.5 2 PMID:23003572;PMID:26443058 -3.1.1.2 phenyl acetate homo sapiens 4778.0 819.8 18 PMID:16128586;PMID:16407305;PMID:1673383;PMID:18951406;PMID:20176005;PMID:24096087;PMID:24123308;PMID:25107406;PMID:33348669 -3.1.1.2 phenyl acetate saccharolobus solfataricus 521.0 521.0 1 PMID:18931117 -3.1.1.2 phenyl acetate sulfolobus acidocaldarius 0.35 0.35 1 PMID:24894602 -3.1.1.2 propyl acetate homo sapiens 0.4 0.4 1 PMID:15835926 -3.1.1.2 s-methyl thiobutanoate gluconobacter oxydans 20.0 14.65 2 PMID:23003572;PMID:26443058 -3.1.1.20 (-)-catechin gallate aspergillus oryzae 9.5 9.5 1 PMID:29859669 -3.1.1.20 (-)-epicatechin gallate aspergillus oryzae 9.3 9.3 1 PMID:29859669 -3.1.1.20 (-)-epigallocatechin gallate aspergillus oryzae 7.0 7.0 1 PMID:29859669 -3.1.1.20 (-)-gallocatechin gallate aspergillus oryzae 8.5 8.5 1 PMID:29859669 -3.1.1.20 beta-glucogallin clostridium butyricum 459.0 213.0 3 PMID:35202648 -3.1.1.20 catechin gallate aspergillus oryzae 79.8 72.15 2 PMID:24856589 -3.1.1.20 catechin gallate lactiplantibacillus paraplantarum 8.1 8.1 1 PMID:24708557 -3.1.1.20 catechin gallate lactiplantibacillus pentosus 1.48 1.48 1 PMID:24708557 -3.1.1.20 catechin gallate lactiplantibacillus plantarum 2.41 2.41 1 PMID:24708557 -3.1.1.20 epicatechin gallate aspergillus oryzae 103.4 85.45 2 PMID:24856589 -3.1.1.20 epicatechin gallate herbaspirillum camelliae 34.5 34.5 1 PMID:34641872 -3.1.1.20 epicatechin gallate lactiplantibacillus paraplantarum 11.08 11.08 1 PMID:24708557 -3.1.1.20 epicatechin gallate lactiplantibacillus pentosus 0.42 0.42 1 PMID:24708557 -3.1.1.20 epicatechin gallate lactiplantibacillus plantarum 1.49 1.49 1 PMID:24708557 -3.1.1.20 epigallocatechin gallate aspergillus oryzae 86.1 74.1 2 PMID:24856589 -3.1.1.20 epigallocatechin gallate herbaspirillum camelliae 37.8 37.8 1 PMID:34641872 -3.1.1.20 epigallocatechin gallate lactiplantibacillus paraplantarum 14.29 14.29 1 PMID:24708557 -3.1.1.20 epigallocatechin gallate lactiplantibacillus pentosus 0.44 0.44 1 PMID:24708557 -3.1.1.20 epigallocatechin gallate lactiplantibacillus plantarum 1.12 1.12 1 PMID:24708557 -3.1.1.20 epigallocatechin-3-o-(3-o-methyl) gallate lactiplantibacillus paraplantarum 0.35 0.35 1 PMID:24708557 -3.1.1.20 epigallocatechin-3-o-(3-o-methyl) gallate lactiplantibacillus pentosus 0.06 0.06 1 PMID:24708557 -3.1.1.20 epigallocatechin-3-o-(3-o-methyl) gallate lactiplantibacillus plantarum 0.26 0.26 1 PMID:24708557 -3.1.1.20 ethyl gallate aspergillus oryzae 19.0 14.4 2 PMID:24856589 -3.1.1.20 ethyl gallate lachnospiraceae 78.8 78.8 1 PMID:34976993 -3.1.1.20 ethyl protocatechuate aspergillus oryzae 0.39 0.39 1 PMID:29859669 -3.1.1.20 gallocatechin gallate lactiplantibacillus paraplantarum 9.2 9.2 1 PMID:24708557 -3.1.1.20 gallocatechin gallate lactiplantibacillus pentosus 1.12 1.12 1 PMID:24708557 -3.1.1.20 gallocatechin gallate lactiplantibacillus plantarum 0.89 0.89 1 PMID:24708557 -3.1.1.20 gallotannin aspergillus niger 4.2 4.2 1 * -3.1.1.20 lauryl gallate lachnospiraceae 24.6 24.6 1 PMID:34976993 -3.1.1.20 methyl gallate aspergillus fumigatus 152.86 152.86 1 PMID:29868308 -3.1.1.20 methyl gallate aspergillus niger 2611.0 590.75 10 PMID:21837378 -3.1.1.20 methyl gallate aspergillus oryzae 70.2 60.2 3 PMID:24856589;PMID:29859669 -3.1.1.20 methyl gallate clostridium butyricum 187.0 45.9 3 PMID:35202648 -3.1.1.20 methyl gallate herbaspirillum camelliae 14.8 14.8 1 PMID:34641872 -3.1.1.20 methyl gallate lachnospiraceae 82.5 82.5 1 PMID:34976993 -3.1.1.20 methyl gallate lactiplantibacillus paraplantarum 72.73 72.73 1 PMID:24708557 -3.1.1.20 methyl gallate lactiplantibacillus pentosus 15.95 15.95 1 PMID:24708557 -3.1.1.20 methyl gallate lactiplantibacillus plantarum 99.4 74.0 3 PMID:23836494;PMID:24708557;PMID:30232563 -3.1.1.20 methyl gallate streptomyces sviceus 69.9 69.9 1 PMID:30232563 -3.1.1.20 propyl gallate aspergillus fumigatus 111.93 111.93 1 PMID:29868308 -3.1.1.20 propyl gallate aspergillus oryzae 20.5 19.55 2 PMID:24856589 -3.1.1.20 propyl gallate clostridium butyricum 136.0 32.0 3 PMID:35202648 -3.1.1.20 propyl gallate lachnospiraceae 44.2 44.2 1 PMID:34976993 -3.1.1.20 tannic acid aspergillus fumigatus 362.24 362.24 1 PMID:29868308 -3.1.1.20 tannic acid aspergillus oryzae 551.4 551.4 1 PMID:27373426 -3.1.1.20 tannic acid lachnospiraceae 82.1 82.1 1 PMID:34976993 -3.1.1.20 tannic acid lactiplantibacillus plantarum 62.6 62.6 1 PMID:30232563 -3.1.1.20 tannic acid streptomyces sviceus 64.7 64.7 1 PMID:30232563 -3.1.1.22 (r)-3-((r)-3-hydroxybutanoyloxy)2butanoate paucimonas lemoignei 80.0 80.0 1 PMID:17964488 -3.1.1.22 (r)-3-((r)-3-hydroxybutanoyloxy)3butanoate paucimonas lemoignei 22.0 22.0 1 PMID:17964488 -3.1.1.22 (r)-3-((r)-3-hydroxybutanoyloxy)butanoate paucimonas lemoignei 1500.0 1500.0 1 PMID:17964488 -3.1.1.23 2-arachidonoylglycerol homo sapiens 570000.0 570000.0 1 PMID:26555264 -3.1.1.23 2-arachidonoylglycerol rattus norvegicus 0.35 0.35 1 PMID:17649977 -3.1.1.23 4-methylumbelliferyl butyrate homo sapiens 1.13 1.13 1 PMID:21308848 -3.1.1.23 arachidonoyl-1-thio-glycerol bacillus sp. (in: firmicutes) 2.66 2.66 1 PMID:24894647 -3.1.1.23 prostaglandin d2-g rattus norvegicus 0.07 0.07 1 PMID:17649977 -3.1.1.23 prostaglandin e2-g rattus norvegicus 0.16 0.16 1 PMID:17649977 -3.1.1.23 prostaglandin f3alpha-g rattus norvegicus 0.14 0.14 1 PMID:17649977 -3.1.1.25 (r)-gamma-valerolactone homo sapiens 36.621 36.621 1 PMID:26146888 -3.1.1.25 3-oxo-decanoyl-l-homoserine lactone vulcanisaeta moutnovskia 0.47 0.47 1 PMID:25670483 -3.1.1.25 3-oxo-dodecanoyl l-homoserine lactone homo sapiens 4.1 4.1 1 PMID:32382056 -3.1.1.25 3-oxo-octanoyl-l-homoserine lactone vulcanisaeta moutnovskia 0.35 0.35 1 PMID:25670483 -3.1.1.25 4-methoxy phenyl acetate homo sapiens 39.0 39.0 1 PMID:15835926 -3.1.1.25 5-(thiobutyl)butyrolactone homo sapiens 116.0 116.0 1 PMID:16407305 -3.1.1.25 5-butyl-4-methyldihydro-2(3h)-furanone vulcanisaeta moutnovskia 4.2 4.2 1 PMID:24858677 -3.1.1.25 5-thiobutyl-gamma-butyrolactone homo sapiens 1.1 1.1 1 PMID:32382056 -3.1.1.25 7-oxo-n-(2-oxotetrahydrofuran-3-yl)nonanamide sulfolobus acidocaldarius 0.89 0.89 1 PMID:24894602 -3.1.1.25 9-oxo-n-(2-oxotetrahydrofuran-3-yl)undecanamide sulfolobus acidocaldarius 1.03 1.03 1 PMID:24894602 -3.1.1.25 delta-dodecalactone vulcanisaeta moutnovskia 28.08 28.08 1 PMID:25670483 -3.1.1.25 delta-nonalactone homo sapiens 48.0 48.0 1 PMID:15835926 -3.1.1.25 delta-nonalactone saccharolobus solfataricus 15.32 15.32 1 PMID:24086491 -3.1.1.25 delta-nonalactone vulcanisaeta moutnovskia 88.91 88.91 1 PMID:25670483 -3.1.1.25 delta-undecalactone vulcanisaeta moutnovskia 60.78 60.78 1 PMID:25670483 -3.1.1.25 delta-undecanolactone saccharolobus solfataricus 12.65 10.015 2 PMID:24086491 -3.1.1.25 delta-valerolactone homo sapiens 632.0 210.0 7 PMID:15835926;PMID:16128586;PMID:16407305;PMID:18951406;PMID:25107406 -3.1.1.25 delta-valerolactone saccharolobus islandicus 0.43 0.43 1 PMID:23071703 -3.1.1.25 dihydrocoumarin homo sapiens 152.0 151.0 2 PMID:15835926;PMID:33348669 -3.1.1.25 dihydrocoumarin saccharolobus solfataricus 7.32 7.32 1 PMID:24086491 -3.1.1.25 dodecanoic-1,4-lactone sulfolobus acidocaldarius 0.53 0.53 1 PMID:24894602 -3.1.1.25 dodecanoic-1,5-lactone sulfolobus acidocaldarius 3.34 3.34 1 PMID:24894602 -3.1.1.25 dodecanoic-delta-lactone saccharolobus islandicus 11.09 11.09 1 PMID:23071703 -3.1.1.25 dodecanoic-gamma-lactone saccharolobus islandicus 1.5 1.5 1 PMID:23071703 -3.1.1.25 epsilon-caprolactone saccharolobus islandicus 7.27 7.27 1 PMID:23071703 -3.1.1.25 epsilon-caprolactone saccharolobus solfataricus 4.45 4.45 1 PMID:24086491 -3.1.1.25 epsilon-caprolactone sulfolobus acidocaldarius 15.04 15.04 1 PMID:24894602 -3.1.1.25 gamma-(r)-caprolactone vulcanisaeta moutnovskia 3.04 3.04 1 PMID:24858677 -3.1.1.25 gamma-(r)-valerolactone vulcanisaeta moutnovskia 6.23 6.23 1 PMID:24858677 -3.1.1.25 gamma-(s)-caprolactone vulcanisaeta moutnovskia 1.89 1.89 1 PMID:24858677 -3.1.1.25 gamma-(s)-valerolactone vulcanisaeta moutnovskia 2.68 2.68 1 PMID:24858677 -3.1.1.25 gamma-butyrolactone homo sapiens 147.209 111.0 3 PMID:15835926;PMID:18951406;PMID:26146888 -3.1.1.25 gamma-butyrolactone saccharolobus islandicus 5.75 5.75 1 PMID:23071703 -3.1.1.25 gamma-butyrolactone vulcanisaeta moutnovskia 2.79 2.79 1 PMID:24858677 -3.1.1.25 gamma-caprolactone homo sapiens 44.0 44.0 2 PMID:15835926;PMID:16407305 -3.1.1.25 gamma-caprolactone vulcanisaeta moutnovskia 112.3 112.3 1 PMID:25670483 -3.1.1.25 gamma-dodecalactone vulcanisaeta moutnovskia 0.16 0.16 1 PMID:25670483 -3.1.1.25 gamma-dodecanoic acid lactone homo sapiens 26.4 26.4 1 PMID:15835926 -3.1.1.25 gamma-dodecanoic lactone homo sapiens 101.0 67.5 2 PMID:16128586 -3.1.1.25 gamma-dodecanolactone saccharolobus solfataricus 2.72 2.72 1 PMID:24086491 -3.1.1.25 gamma-heptalactone vulcanisaeta moutnovskia 27.25 27.25 1 PMID:25670483 -3.1.1.25 gamma-heptanolactone saccharolobus solfataricus 2.92 2.92 1 PMID:24086491 -3.1.1.25 gamma-heptanolide homo sapiens 34.0 34.0 1 PMID:15835926 -3.1.1.25 gamma-heptanolide saccharolobus islandicus 5.9 5.9 1 PMID:23071703 -3.1.1.25 gamma-heptanolide sulfolobus acidocaldarius 10.25 10.25 1 PMID:24894602 -3.1.1.25 gamma-nonalactone homo sapiens 31.0 31.0 1 PMID:16407305 -3.1.1.25 gamma-nonalactone saccharolobus solfataricus 5.54 5.54 1 PMID:24086491 -3.1.1.25 gamma-nonalactone vulcanisaeta moutnovskia 44.49 44.49 1 PMID:25670483 -3.1.1.25 gamma-nonanoic acid lactone homo sapiens 31.0 31.0 1 PMID:15835926 -3.1.1.25 gamma-undecalactone vulcanisaeta moutnovskia 8.86 8.86 1 PMID:25670483 -3.1.1.25 gamma-undecanoic acid lactone homo sapiens 62.0 62.0 1 PMID:15835926 -3.1.1.25 gamma-undecanoiclactone homo sapiens 62.0 62.0 1 PMID:18951406 -3.1.1.25 gamma-undecanolactone saccharolobus solfataricus 4.95 4.95 1 PMID:24086491 -3.1.1.25 n-(2-oxotetrahydrofuran-3-yl)pentanamide sulfolobus acidocaldarius 0.94 0.94 1 PMID:24894602 -3.1.1.25 n-(3-oxodecanoyl)-dl-homoserine lactone saccharolobus islandicus 10.65 10.65 1 PMID:23071703 -3.1.1.25 n-(3-oxodecanoyl)-l-homoserine lactone saccharolobus solfataricus 4.52 4.52 1 PMID:24086491 -3.1.1.25 n-(3-oxododecanoyl)-dl-homoserine lactone saccharolobus islandicus 0.39 0.39 1 PMID:23071703 -3.1.1.25 n-(3-oxododecanoyl)-l-homoserine lactone saccharolobus solfataricus 1.01 1.01 1 PMID:24086491 -3.1.1.25 n-(3-oxohexanoyl)-l-homoserine lactone saccharolobus solfataricus 0.083 0.083 1 PMID:24086491 -3.1.1.25 n-(3-oxohexanoyl)-l-homoserine lactone uncultured marine bacterium 1.3 1.3 1 PMID:34910563 -3.1.1.25 n-(3-oxohexanoyl)homoserine lactone saccharolobus solfataricus 0.041 0.041 1 PMID:24086491 -3.1.1.25 n-(3-oxooctanoyl)-dl-homoserine lactone saccharolobus islandicus 4.1 4.1 1 PMID:23071703 -3.1.1.25 n-(3-oxooctanoyl)-dl-homoserine lactone uncultured marine bacterium 0.519 0.519 1 PMID:34910563 -3.1.1.25 n-(3-oxooctanoyl)-l-homoserine lactone saccharolobus solfataricus 0.54 0.54 1 PMID:24086491 -3.1.1.25 n-(3-oxooctanoyl)homoserine lactone saccharolobus solfataricus 0.42 0.42 1 PMID:24086491 -3.1.1.25 n-butyryl-l-homoserine lactone uncultured marine bacterium 1.85 1.85 1 PMID:34910563 -3.1.1.25 n-dodecanoyl-dl-homoserine lactone saccharolobus islandicus 1.9 1.9 1 PMID:23071703 -3.1.1.25 n-dodecanoylhomoserine lactone saccharolobus solfataricus 1.7 1.7 1 PMID:24086491 -3.1.1.25 n-heptanoyl-l-homoserine lactone uncultured marine bacterium 0.23 0.23 1 PMID:34910563 -3.1.1.25 n-hexanoylhomoserine lactone saccharolobus solfataricus 0.36 0.36 1 PMID:24086491 -3.1.1.25 n-octanoyl-dl-homoserine lactone saccharolobus islandicus 0.71 0.71 1 PMID:23071703 -3.1.1.25 n-octanoylhomoserine lactone saccharolobus solfataricus 1.0 1.0 1 PMID:24086491 -3.1.1.25 nonanoic-1,4-lactone sulfolobus acidocaldarius 2.64 2.64 1 PMID:24894602 -3.1.1.25 nonanoic-1,5-lactone sulfolobus acidocaldarius 4.55 4.55 1 PMID:24894602 -3.1.1.25 nonanoic-delta-lactone saccharolobus islandicus 51.7 51.7 1 PMID:23071703 -3.1.1.25 nonanoic-gamma-lactone saccharolobus islandicus 3.1 3.1 1 PMID:23071703 -3.1.1.25 octanoyl-l-homoserine lactone vulcanisaeta moutnovskia 0.59 0.59 1 PMID:25670483 -3.1.1.25 pantoyl lactone homo sapiens 11.9 11.9 1 PMID:15835926 -3.1.1.25 paraoxon saccharolobus solfataricus 12.6 12.6 1 PMID:24086491 -3.1.1.25 undecanoic-1,4-lactone sulfolobus acidocaldarius 0.34 0.34 1 PMID:24894602 -3.1.1.25 undecanoic-1,5-lactone sulfolobus acidocaldarius 1.05 1.05 1 PMID:24894602 -3.1.1.25 undecanoic-delta-lactone saccharolobus islandicus 17.65 17.65 1 PMID:23071703 -3.1.1.25 undecanoic-gamma-lactone saccharolobus islandicus 2.15 2.15 1 PMID:23071703 -3.1.1.25 zearalenone clonostachys rosea 0.299 0.299 1 * -3.1.1.26 1,2-diacyl-3-o-alpha-d-galactosyl-(1->6)-beta-d-galactosyl-sn-glycerol parachlorella kessleri 1390.0 944.0 2 PMID:29299622 -3.1.1.27 4-pyridoxate mesorhizobium loti 1.4 1.4 1 PMID:16226926 -3.1.1.27 4-pyridoxolactone mesorhizobium loti 12.2 12.2 1 PMID:16226926 -3.1.1.29 acetyl-his-trna saccharolobus solfataricus 3.4 3.4 1 PMID:12799450 -3.1.1.29 acetyl-histidyl-trna saccharolobus solfataricus 3.4 3.4 1 PMID:12799450 -3.1.1.29 acetyl-histidyl-trnahis saccharolobus solfataricus 3.4 3.4 1 PMID:12799450 -3.1.1.29 dephosphorylated diacyl-lysine-trna saccharolobus solfataricus 6.08 3.47 2 PMID:12799450 -3.1.1.29 dephosphorylated formyl-methioninyl-trna saccharolobus solfataricus 3.0 3.0 1 PMID:12799450 -3.1.1.29 diacetyl-lys-trna homo sapiens 1.3 1.3 1 PMID:14660562 -3.1.1.29 diacetyl-lys-trnalys escherichia coli 3.6 2.225 2 PMID:9303320 -3.1.1.29 diacetyl-lys-trnalys saccharolobus solfataricus 1.8 1.33 2 PMID:12799450 -3.1.1.29 diacetyl-lysine-trna escherichia coli 3.6 3.6 1 PMID:14660562 -3.1.1.29 diacetyl-lysine-trna homo sapiens 1.3 1.3 1 PMID:14660562 -3.1.1.29 diacetyl-lysine-trna saccharolobus solfataricus 1.8 1.8 2 PMID:12799450;PMID:14660562 -3.1.1.29 diacetyl-lysyl-trnalys mycobacterium tuberculosis 1.22 1.22 1 PMID:17516842 -3.1.1.29 diacetyl-lysyl-trnalys saccharolobus solfataricus 1.8 1.8 3 PMID:12799450 -3.1.1.29 formyl-met-trnafmet saccharolobus solfataricus 3.0 3.0 1 PMID:12799450 -3.1.1.29 formyl-methioninyl-trna saccharolobus solfataricus 3.0 3.0 1 PMID:12799450 -3.1.1.29 formyl-methionyl-trna saccharolobus solfataricus 3.0 3.0 1 PMID:12799450 -3.1.1.29 formyl-methionyl-trnafmet saccharolobus solfataricus 3.0 3.0 1 PMID:12799450 -3.1.1.29 n-acetyl-ala-trna(ala) escherichia coli 11.7 11.7 1 PMID:22923517 -3.1.1.29 n-acetyl-met-trna escherichia coli 0.7 0.7 1 PMID:7690473 -3.1.1.29 oregon green-methionine-trna escherichia coli 9.3 9.3 1 PMID:15078105 -3.1.1.3 1-monolaurin rhizomucor miehei 0.0055 0.0055 1 PMID:36748100 -3.1.1.3 4-methylumbelliferyl butyrate penaeus vannamei 200.2 200.2 1 PMID:20965269 -3.1.1.3 4-nitrophenyl acetate oryza sativa 0.44 0.4 2 PMID:23202292 -3.1.1.3 4-nitrophenyl butanoate saccharolobus solfataricus 1135.0 1135.0 1 * -3.1.1.3 4-nitrophenyl butyrate staphylococcus xylosus 0.061 0.061 1 PMID:20387014 -3.1.1.3 4-nitrophenyl butyrate sus scrofa 0.064 0.05 3 PMID:33561462 -3.1.1.3 4-nitrophenyl caprate saccharolobus solfataricus 1576.0 1576.0 1 * -3.1.1.3 4-nitrophenyl caproate fervidobacterium changbaicum 22.7 22.7 1 PMID:21046373 -3.1.1.3 4-nitrophenyl caprylate bacillus pumilus 8335.0 8335.0 1 * -3.1.1.3 4-nitrophenyl laurate enterobacter cloacae 68.59 68.59 1 PMID:36018558 -3.1.1.3 4-nitrophenyl laurate uncultured bacterium 569.0 569.0 1 PMID:21678056 -3.1.1.3 4-nitrophenyl octanoate rhizomucor miehei 24.05 24.05 1 PMID:29101200 -3.1.1.3 4-nitrophenyl palmitate alkalicoccobacillus gibsonii 8.07 6.07 3 PMID:33625538 -3.1.1.3 4-nitrophenyl palmitate amycolatopsis mediterranei 1468.0 1468.0 1 PMID:21145735 -3.1.1.3 4-nitrophenyl palmitate aspergillus nidulans 494.0 494.0 1 PMID:10637060 -3.1.1.3 4-nitrophenyl palmitate pseudomonas reinekei 2601.66 2601.66 1 PMID:30142430 -3.1.1.3 4-nitrophenyl palmitate saccharolobus solfataricus 2252.0 2252.0 1 * -3.1.1.3 eugenol rhizomucor miehei 0.67 0.67 1 PMID:29108626 -3.1.1.3 olive oil sphingobacterium sp. ab3 56000.0 56000.0 1 PMID:36314920 -3.1.1.3 olive oil staphylococcus xylosus 500.0 500.0 1 PMID:17521919 -3.1.1.3 triacetin oryza sativa 0.32 0.21000000000000002 2 PMID:23202292 -3.1.1.3 tributyrin camelus dromedarius 4333.0 4333.0 1 PMID:19195852 -3.1.1.3 tributyrin scorpio maurus 5370.0 5370.0 1 PMID:16154275 -3.1.1.3 tributyrin serratia sp. w3 841.24 686.88 2 * -3.1.1.3 tributyrin staphylococcus xylosus 1900.0 1500.0 3 PMID:16380267;PMID:17521919 -3.1.1.3 trioctanoin camelus dromedarius 2416.0 2416.0 1 PMID:19195852 -3.1.1.3 triolein pseudomonas aeruginosa 3000.0 3000.0 1 PMID:1748875 -3.1.1.31 6-phospho-d-glucono-1,5-lactone giardia duodenalis 31.8 31.8 1 PMID:34442758 -3.1.1.32 high-density lipoprotein homo sapiens 1.1 1.1 1 PMID:18566479 -3.1.1.32 phosphatidic acid streptomyces albidoflavus 630.0 630.0 1 PMID:23772365 -3.1.1.32 phosphatidylcholine serratia sp. (in: enterobacteria) 0.65 0.65 1 PMID:10698747 -3.1.1.32 phosphatidylcholine thermomyces lanuginosus 5158.0 5158.0 1 PMID:27821336 -3.1.1.32 triacylglycerol thermomyces lanuginosus 2270.0 2270.0 1 PMID:27821336 -3.1.1.35 dihydrocoumarin melilotus albus 1670.0 1670.0 1 PMID:14458747 -3.1.1.4 1,2-diheptanoyl-sn-glycero-3-phosphocholine arabidopsis thaliana 3.86 3.86 1 PMID:17692835 -3.1.1.4 1,2-diheptanoyl-sn-glycero-3-phosphorylcholine bos taurus 43.3 23.95 2 PMID:8454568 -3.1.1.4 1,2-dihexanoyl-sn-glycero-3-phosphocholine arabidopsis thaliana 1.71 1.12 2 PMID:17692835 -3.1.1.4 1,2-dioctanoyl-sn-glycero-3-phosphocholine arabidopsis thaliana 4.38 4.38 1 PMID:17692835 -3.1.1.4 1,2-dipalmitoyl-phosphatidylcholine sus scrofa 1.42 1.1684999999999999 2 PMID:3654625;PMID:3754257 -3.1.1.4 p-nitrophenyl propionate aeropyrum pernix 39.0 39.0 1 PMID:15135393 -3.1.1.4 phosphatidylcholine camelus dromedarius 20.3 20.3 1 PMID:35684381 -3.1.1.4 phosphatidylcholine crotalus adamanteus 26.7 26.7 1 * -3.1.1.4 phosphatidylcholine dasyatis pastinaca 187.0 187.0 1 PMID:21329523 -3.1.1.4 phosphatidylethanolamine camelus dromedarius 26.9 26.9 1 PMID:35684381 -3.1.1.4 phosphatidylserine camelus dromedarius 7.5 7.5 1 PMID:35684381 -3.1.1.41 4-methylumbelliferyl acetate thermotoga maritima 63.0 52.85 2 PMID:28097692 -3.1.1.41 4-nitrophenyl acetate thermotoga maritima 96.2 78.25 2 PMID:28097692 -3.1.1.41 7-aminocephalosporanic acid rhodotorula glutinis 576.0 576.0 1 * -3.1.1.41 7-aminocephalosporanic acid thermotoga maritima 24.8 24.3 2 PMID:28097692 -3.1.1.41 benzyloxycarbonyl-7-aminocephalosporanic acid rhodotorula glutinis 534.0 534.0 1 * -3.1.1.41 cephalosporin c rhodotorula glutinis 1370.0 1370.0 1 * -3.1.1.41 cephalothin bacillus subtilis 55.0 55.0 1 * -3.1.1.41 cephapirin bacillus subtilis 80.0 80.0 1 * -3.1.1.41 glucose pentaacetate thermotoga maritima 347.0 335.1 2 PMID:28097692 -3.1.1.41 monochloroacetyl-7-aminocephalosporanic acid rhodotorula glutinis 768.0 768.0 1 * -3.1.1.41 xylose tetraacetate thermotoga maritima 326.0 303.35 2 PMID:28097692 -3.1.1.42 chlorogenate bacillus amyloliquefaciens 275.0 12.06 3 * -3.1.1.42 chlorogenate mycosarcoma maydis 19.0 19.0 1 PMID:27173527 -3.1.1.42 chlorogenate rhizoctonia solani 29.3 29.3 1 PMID:28159727 -3.1.1.42 chlorogenic acid aspergillus niger 22.0 22.0 1 PMID:15607224 -3.1.1.42 methyl caffeate mycosarcoma maydis 1.9 1.9 1 PMID:27173527 -3.1.1.42 methyl ferulate mycosarcoma maydis 7.1 7.1 1 PMID:27173527 -3.1.1.42 methyl p-coumarate mycosarcoma maydis 7.3 7.3 1 PMID:27173527 -3.1.1.42 methyl p-coumarate rhizoctonia solani 33.1 33.1 1 PMID:28159727 -3.1.1.43 (r)-4-hydroxyphenylglycine methyl ester xanthomonas campestris pv. campestris 44.0 44.0 1 * -3.1.1.43 (r)-phenylglycine methyl ester xanthomonas campestris pv. campestris 970.0 970.0 1 * -3.1.1.43 4-carbamimidamidobenzyl l-isoleucinate homo sapiens 14.0 14.0 1 PMID:19957998 -3.1.1.43 4-carbamimidamidobenzyl l-phenylalaninate homo sapiens 345.0 345.0 1 PMID:19957998 -3.1.1.43 4-carbamimidamidobenzyl l-valinate homo sapiens 154.0 154.0 1 PMID:19957998 -3.1.1.43 4-hydroxy-d-phenylglycine methyl ester acetobacter pasteurianus 263.0 263.0 1 * -3.1.1.43 amoxicillin acetobacter pasteurianus 10.0 10.0 2 PMID:11772629 -3.1.1.43 amoxicillin xanthomonas campestris pv. campestris 0.51 0.51 1 * -3.1.1.43 ampicillin acetobacter pasteurianus 162.0 162.0 3 PMID:11772629 -3.1.1.43 ampicillin xanthomonas campestris 72.5 72.5 1 * -3.1.1.43 ampicillin xanthomonas campestris pv. campestris 72.5 72.5 1 * -3.1.1.43 ampicillin xanthomonas citri 58.0 58.0 1 * -3.1.1.43 ampicillin xanthomonas sp. 17.5 17.5 1 * -3.1.1.43 cefadroxil acetobacter pasteurianus 347.0 178.3 2 PMID:11772629 -3.1.1.43 cefadroxil xanthomonas campestris pv. campestris 3.5 3.5 1 * -3.1.1.43 cefaloglycin acetobacter pasteurianus 9.6 9.6 1 * -3.1.1.43 cefatrizine xanthomonas citri 2.3 2.3 1 * -3.1.1.43 cephalexin acetobacter pasteurianus 347.0 310.5 2 PMID:11772629;PMID:12011065 -3.1.1.43 cephalexin xanthomonas campestris 200.0 200.0 1 * -3.1.1.43 cephalexin xanthomonas campestris pv. campestris 200.0 200.0 1 * -3.1.1.43 cephalexin xanthomonas citri 3200.0 3200.0 3 * -3.1.1.43 cephalexin xanthomonas sp. 71.0 71.0 1 * -3.1.1.43 d-2-nitro-5-[(phenylglycyl)amino]benzoic acid acetobacter pasteurianus 0.4 0.4 1 PMID:11772629 -3.1.1.43 d-4-hydroxyphenylglycine methyl ester paracidovorax avenae 147.0 147.0 1 PMID:22648687 -3.1.1.43 d-alpha-phenylglycine methyl ester xanthomonas citri 11100.0 8850.0 2 * -3.1.1.43 d-phenylglycine amide acetobacter pasteurianus 43.0 43.0 2 PMID:11772629 -3.1.1.43 d-phenylglycine amide xanthomonas citri 1.6 1.6 1 * -3.1.1.43 d-phenylglycine methyl ester acetobacter pasteurianus 1040.0 1035.0 3 PMID:11772629 -3.1.1.43 d-phenylglycine methyl ester xanthomonas campestris 982.0 982.0 1 * -3.1.1.43 d-phenylglycine methyl ester xanthomonas citri 1860.0 1480.0 2 * -3.1.1.43 d-phenylglycine methyl ester xanthomonas sp. 1000.0 1000.0 1 * -3.1.1.43 phenylalanine [3-(hydroxymethyl)phenyl]guanidine homo sapiens 345.0 345.0 1 PMID:21028903 -3.1.1.43 phenylalanine benzyl ester homo sapiens 395.0 395.0 1 PMID:21028903 -3.1.1.43 phenylalanine ethyl ester homo sapiens 93.0 93.0 1 PMID:21028903 -3.1.1.43 phenylalanine methyl ester homo sapiens 228.0 228.0 1 PMID:21028903 -3.1.1.43 phenylalanine methylester bacillus mycoides 6160.0 6160.0 1 PMID:11432787 -3.1.1.43 valacyclovir homo sapiens 126.0 68.5 4 PMID:19957998;PMID:21028903 -3.1.1.43 valganciclovir homo sapiens 101.0 101.0 1 * -3.1.1.43 valine 4-nitrobenzyl ester homo sapiens 130.0 130.0 1 PMID:21028903 -3.1.1.43 valine [3-(aminomethyl)phenyl]guanidine homo sapiens 0.0023 0.0023 1 PMID:21028903 -3.1.1.43 valine [3-(hydroxymethyl)phenyl]guanidine homo sapiens 154.0 154.0 1 PMID:21028903 -3.1.1.43 valine benzyl ester homo sapiens 60.0 60.0 1 PMID:21028903 -3.1.1.45 4-carboxymethylenebut-2-en-4-olide pseudomonas knackmussii 30.0 30.0 1 PMID:3804973 -3.1.1.45 4-fluoromuconolactone pseudomonas sp. 1633.0 1631.5 2 PMID:14617643 -3.1.1.45 cis-4-carboxymethylenebut-2-chloro-2-en-4-olide rhodococcus opacus 19.8 19.8 1 * -3.1.1.45 cis-4-carboxymethylenebut-2-en-4-olide burkholderia cepacia 817.0 817.0 1 PMID:7684040 -3.1.1.45 cis-4-carboxymethylenebut-2-en-4-olide pseudomonas knackmussii 260.0 260.0 1 PMID:9440530 -3.1.1.45 cis-4-carboxymethylenebut-2-en-4-olide rhodococcus opacus 15.4 15.4 1 * -3.1.1.45 cis-4-carboxymethylenebut-2-methyl-2-en-4-olide rhodococcus opacus 4.95 4.95 1 * -3.1.1.45 e-dienelactone pseudomonas sp. 14.0 14.0 1 * -3.1.1.45 protoanemonin pseudomonas knackmussii 2.08 2.08 1 PMID:9440530 -3.1.1.45 trans-4-carboxymethylenebut-2-en-4-olide pseudomonas knackmussii 15.0 9.17 3 PMID:1866431 -3.1.1.45 trans-dienelactone pseudomonas reinekei 15100.0 15100.0 1 PMID:18789896 -3.1.1.45 trans-dienelactone pseudomonas sp. 2650.0 2650.0 1 PMID:14617643 -3.1.1.45 trans-dienelactone saccharolobus solfataricus 9409.0 9409.0 1 PMID:20655986 -3.1.1.45 z-dienelactone pseudomonas sp. 19.0 19.0 1 * -3.1.1.47 1-acetyl-2-hexadecyl-sn-glycero-3-phosphocholine homo sapiens 8.1 4.6 2 PMID:11294621 -3.1.1.47 1-oleoyl-2-acetyl-sn-glycerol homo sapiens 3.0 1.625 2 PMID:11294621 -3.1.1.47 2-acetyl-1-hexadecyl-sn-glycero-3-phosphocholine homo sapiens 24.6 3.2 3 PMID:11294621 -3.1.1.47 2-acetyl-1-octadecyl-sn-glycero-3-phosphocholine homo sapiens 6.08 4.8 3 PMID:11294621 -3.1.1.47 octyl acetate homo sapiens 6.08 1.295 4 PMID:11294621 -3.1.1.47 triacetylglycerol homo sapiens 37.0 16.5 3 PMID:11294621 -3.1.1.5 1-hexyl-glycerophosphocholine pseudomonas aeruginosa 1016.0 1016.0 1 PMID:23874889 -3.1.1.5 1-lauryl-glycerophosphocholine pseudomonas aeruginosa 1975.0 1975.0 1 PMID:23874889 -3.1.1.5 1-palmitoyl-glycerophosphocholine pseudomonas aeruginosa 921.1 921.1 1 PMID:23874889 -3.1.1.5 4-nitrophenyl palmitate caldibacillus thermoamylovorans 227.3 227.3 1 PMID:29051101 -3.1.1.53 4-nitrophenyl acetate tannerella forsythia 111.0 111.0 1 PMID:26378150 -3.1.1.56 diethyl 4-nitrophenyl phosphate saccharomyces cerevisiae 0.0067 0.0067 1 PMID:18707125 -3.1.1.56 dimethyl 4-nitrophenyl phosphate saccharomyces cerevisiae 0.00483 0.00483 1 PMID:18707125 -3.1.1.56 p-nitrophenyl acetate saccharomyces cerevisiae 1.783 1.783 1 PMID:18707125 -3.1.1.56 p-nitrophenyl butyrate saccharomyces cerevisiae 0.198 0.198 1 PMID:18707125 -3.1.1.57 2-pyrone-4,6-dicarboxylate sphingomonas paucimobilis 342.0 342.0 1 PMID:22475079 -3.1.1.58 3-carboxyumbelliferyl acetate staphylococcus epidermidis 0.0013 0.0013 1 PMID:23866051 -3.1.1.58 beta-1,6-linked n-acetylglucosamine pentamer staphylococcus epidermidis 0.0007 0.0007 1 PMID:23866051 -3.1.1.58 beta-1,6-linked n-acetylglucosamine trimer staphylococcus epidermidis 0.0007 0.0007 1 PMID:23866051 -3.1.1.59 alpha-naphthyl acetate manduca sexta 22.0 22.0 1 PMID:20307057 -3.1.1.59 juvenile hormone rhyparobia maderae 0.39 0.245 2 PMID:10876123 -3.1.1.59 juvenile hormone i drosophila melanogaster 1.6 1.6 1 PMID:17517331 -3.1.1.59 juvenile hormone i trichoplusia ni 0.618 0.618 1 * -3.1.1.59 juvenile hormone iii bombyx mori 1.0 0.509 2 PMID:20060470 -3.1.1.59 juvenile hormone iii drosophila melanogaster 1.1 1.0 3 PMID:17517331 -3.1.1.59 juvenile hormone iii leptinotarsa decemlineata 1.9 1.4 2 PMID:9177132 -3.1.1.59 juvenile hormone iii manduca sexta 0.7 0.7 1 PMID:20307057 -3.1.1.59 juvenile hormone iii tribolium castaneum 0.164 0.164 1 PMID:20522120 -3.1.1.59 juvenile hormone iii trichoplusia ni 0.323 0.323 1 * -3.1.1.59 methyl farnesoate drosophila melanogaster 3.0 3.0 1 PMID:17517331 -3.1.1.59 saturated juvenile hormone iii manduca sexta 0.7 0.7 1 PMID:20307057 -3.1.1.6 2-benzylcyclohex-1-en-1-yl acetate marchantia polymorpha 33.0 26.5 2 * -3.1.1.6 2-ethylcyclohex-1-en-1-yl acetate marchantia polymorpha 63.0 63.0 1 * -3.1.1.6 2-isopropylcyclohex-1-en-1-yl acetate marchantia polymorpha 14.0 14.0 1 * -3.1.1.6 2-methylcyclohex-1-en-1-yl acetate marchantia polymorpha 77.0 77.0 1 * -3.1.1.6 2-n-pentylcyclohex-1-en-1-yl acetate marchantia polymorpha 42.0 34.0 2 * -3.1.1.6 2-n-propylcyclohex-1-en-1-yl acetate marchantia polymorpha 79.0 79.0 1 * -3.1.1.6 2-o-acetyl 4-nitrophenyl beta-d-xylopyranoside cellvibrio japonicus 41.6 41.6 1 PMID:19968989 -3.1.1.6 2-o-acetyl-4-nitrophenyl beta-d-xylopyranoside thermotoga maritima 76.1 76.1 1 PMID:22411095 -3.1.1.6 2-t-butylcyclohex-1-en-1-yl acetate marchantia polymorpha 17.0 12.0 2 * -3.1.1.6 3-o-acetyl 4-nitrophenyl beta-d-xylopyranoside cellvibrio japonicus 2101.0 2101.0 1 PMID:19968989 -3.1.1.6 3-o-acetyl-4-nitrophenyl beta-d-xylopyranoside thermotoga maritima 70.1 70.1 1 PMID:22411095 -3.1.1.6 4-nitrophenyl acetate alicyclobacillus tolerans 1213.4 1213.4 1 PMID:31954783 -3.1.1.6 4-nitrophenyl acetate escherichia coli 0.82 0.82 1 * -3.1.1.6 4-nitrophenyl acetate exiguobacterium antarcticum 497.4 497.4 1 PMID:31229546 -3.1.1.6 4-nitrophenyl acetate pantoea dispersa 40900.0 36407.0 2 PMID:31127451 -3.1.1.6 4-nitrophenyl acetate phocaeicola vulgatus 75.0 75.0 1 PMID:35503212 -3.1.1.6 4-nitrophenyl acetate pseudomonas putida 5.5 5.5 1 PMID:27696534 -3.1.1.6 4-nitrophenyl acetate talaromyces pinophilus 49.2 49.2 1 PMID:25825334 -3.1.1.6 4-nitrophenyl acetate thermotoga maritima 57.5 57.5 1 PMID:22411095 -3.1.1.6 4-nitrophenyl butanoate alicyclobacillus tolerans 186.9 186.9 1 PMID:31954783 -3.1.1.6 4-nitrophenyl butanoate exiguobacterium antarcticum 303.9 303.9 1 PMID:31229546 -3.1.1.6 4-nitrophenyl butyrate escherichia coli 29.0 29.0 2 PMID:23132590 -3.1.1.6 4-nitrophenyl butyrate talaromyces pinophilus 29.8 29.8 1 PMID:25825334 -3.1.1.6 4-nitrophenyl hexanoate escherichia coli 34.5 34.5 1 PMID:17305603 -3.1.1.6 4-nitrophenyl hexanoate exiguobacterium antarcticum 58.2 58.2 1 PMID:31229546 -3.1.1.6 4-nitrophenyl propionate thermotoga maritima 41.3 41.3 1 PMID:22411095 -3.1.1.6 4-nitrophenyl-2-o-acetyl-alpha-l-arabinofuranoside aspergillus oryzae 0.15 0.15 1 PMID:16901567 -3.1.1.6 4-nitrophenyl-2-o-acetyl-beta-d-xylopyranoside aspergillus oryzae 3.23 3.23 1 PMID:16901567 -3.1.1.6 4-nitrophenyl-3-o-acetyl-beta-d-xylopyranoside aspergillus oryzae 1.9 1.9 1 PMID:16901567 -3.1.1.6 4-nitrophenyl-4-o-acetyl-beta-d-xylopyranoside aspergillus oryzae 0.91 0.91 1 PMID:16901567 -3.1.1.6 4-nitrophenyl-5-o-acetyl-alpha-l-arabinofuranoside aspergillus oryzae 1.77 1.77 1 PMID:16901567 -3.1.1.6 4-nitrophenyl-butanoate escherichia coli 145.0 83.0 2 PMID:17305603 -3.1.1.6 4-o-acetyl 4-nitrophenyl beta-d-xylopyranoside acetivibrio thermocellus 1331.0 1331.0 1 PMID:19968989 -3.1.1.6 4-o-acetyl 4-nitrophenyl beta-d-xylopyranoside cellvibrio japonicus 3210.0 1725.8 2 PMID:19968989 -3.1.1.6 4-o-acetyl-4-nitrophenyl beta-d-xylopyranoside thermotoga maritima 78.6 78.6 1 PMID:22411095 -3.1.1.6 6-acetylmorphine rhodococcus sp. (in: high g+c gram-positive bacteria) 12.6 12.6 1 PMID:12421810 -3.1.1.6 phenyl acetate rhodococcus sp. (in: high g+c gram-positive bacteria) 3.0 3.0 1 PMID:12421810 -3.1.1.6 tributyrin escherichia coli 6.2 6.2 1 * -3.1.1.60 bis(2-ethylhexyl)phthalate triticum aestivum 8.33e-05 8.33e-05 1 PMID:6468391 -3.1.1.61 methyl-accepting chemotaxis protein salmonella enterica subsp. enterica serovar typhimurium 0.004 0.004 1 PMID:6387376 -3.1.1.61 several methylated protein substrates rattus norvegicus 0.00056 0.00056 1 PMID:2549948 -3.1.1.64 all-trans-retinyl palmitate gallus gallus 0.000145 0.000145 1 PMID:19490105 -3.1.1.64 an all-trans retinyl ester danio rerio 0.00044 0.00044 1 PMID:21235714 -3.1.1.67 oleate oryctolagus cuniculus 0.06 0.04 3 PMID:6487592 -3.1.1.67 oleate rattus norvegicus 0.285 0.285 1 PMID:9049433 -3.1.1.68 d-glucono-1,5-lactone caulobacter vibrioides 0.0024 0.0024 1 PMID:34633186 -3.1.1.68 d-xylono-1,4-lactone caulobacter vibrioides 0.0027 0.0027 1 PMID:34633186 -3.1.1.7 (s)-butyrylthiocholine iodide schizaphis graminum 8.83e-06 8.83e-06 1 PMID:20146377 -3.1.1.7 6-monoacetylmorphine homo sapiens 118.0 118.0 1 PMID:30080993 -3.1.1.7 acetyl thiocholine homo sapiens 6500.0 6500.0 1 PMID:11463350 -3.1.1.7 acetyl(beta-methyl)thiocholine iodide schizaphis graminum 0.000146 0.000146 1 PMID:20146377 -3.1.1.7 acetylcholine cimex lectularius 8e-05 8e-05 2 PMID:30266661 -3.1.1.7 acetylcholine drosophila melanogaster 13700.0 6670.0 3 PMID:3115978 -3.1.1.7 acetylcholine mus musculus 2333.0 2330.0 3 PMID:10779503;PMID:12665427 -3.1.1.7 acetylcholine chloride macroptilium atropurpureum 1.2 1.2 1 PMID:18046576 -3.1.1.7 acetylthiocholine arapaima gigas 1.04 1.04 1 PMID:24980148 -3.1.1.7 acetylthiocholine bactrocera dorsalis 1820.0 1347.5 4 PMID:15315367;PMID:23007913 -3.1.1.7 acetylthiocholine bos taurus 5300.0 5300.0 1 PMID:3980478 -3.1.1.7 acetylthiocholine bungarus fasciatus 4417.0 4417.0 1 PMID:16962835 -3.1.1.7 acetylthiocholine colossoma macropomum 1.29 1.29 1 PMID:24980148 -3.1.1.7 acetylthiocholine homo sapiens 93.0 50.09 2 PMID:29908755;PMID:30993792 -3.1.1.7 acetylthiocholine hoplosternum littorale 8100.0 8100.0 1 PMID:30408655 -3.1.1.7 acetylthiocholine oreochromis niloticus 1.55 1.55 1 PMID:24980148 -3.1.1.7 acetylthiocholine rachycentron canadum 1.84 1.84 1 PMID:24980148 -3.1.1.7 acetylthiocholine chloride macroptilium atropurpureum 0.2 0.2 1 PMID:18046576 -3.1.1.7 acetylthiocholine iodide mus musculus 2670.0 2668.5 2 PMID:11517229 -3.1.1.7 acetylthiocholine iodide schizaphis graminum 0.000143 0.000143 1 PMID:20146377 -3.1.1.7 heroin homo sapiens 35.0 35.0 1 PMID:30080993 -3.1.1.7 propionylcholine chloride macroptilium atropurpureum 1.2 1.2 1 PMID:18046576 -3.1.1.7 propionylthiocholine bactrocera dorsalis 433.0 433.0 1 PMID:15315367 -3.1.1.7 propionylthiocholine homo sapiens 3.72 3.72 1 PMID:29908755 -3.1.1.7 propionylthiocholine chloride macroptilium atropurpureum 0.5 0.5 1 PMID:18046576 -3.1.1.7 propionylthiocholine iodide schizaphis graminum 8.25e-05 8.25e-05 1 PMID:20146377 -3.1.1.7 s-butyrylthiocholine bactrocera dorsalis 111.0 111.0 1 PMID:15315367 -3.1.1.72 1,2,3,4-tetra-o-acetyl-d-xylopyranose arcticibacterium luteifluviistationis 3.6 2.0 5 PMID:34058201 -3.1.1.72 1-naphthyl acetate aspergillus awamori 81.9 41.215 2 PMID:15848131 -3.1.1.72 2-naphthyl acetate aspergillus oryzae 4.5 4.5 1 PMID:34376338 -3.1.1.72 2-naphthyl acetate uncultured microorganism 133.3 133.3 1 PMID:27702488 -3.1.1.72 2-naphthyl propionate aspergillus oryzae 18.0 18.0 1 PMID:34376338 -3.1.1.72 2-o-acetyl-4-nitrophenyl beta-d-xylopyranoside streptomyces lividans 118.0 118.0 1 PMID:16431911 -3.1.1.72 4-methylumbelliferyl acetate aspergillus nidulans 163.0 129.5 2 PMID:28591625 -3.1.1.72 4-methylumbelliferyl acetate bacteroides thetaiotaomicron 0.727 0.727 1 PMID:34074097 -3.1.1.72 4-methylumbelliferyl acetate flavobacterium johnsoniae 95.1 95.1 1 PMID:29588659 -3.1.1.72 4-methylumbelliferyl acetate irpex lacteus 33.8 33.8 1 PMID:34429691 -3.1.1.72 4-methylumbelliferyl acetate uncultured microorganism 166.7 166.7 1 PMID:27702488 -3.1.1.72 4-methylumbelliferyl acetate volvariella volvacea 485.0 470.5 2 PMID:27770795 -3.1.1.72 4-nitrophenyl acetate arion ater 122.4 122.4 1 PMID:35566348 -3.1.1.72 4-nitrophenyl acetate aspergillus nidulans 59.0 55.0 2 PMID:28591625 -3.1.1.72 4-nitrophenyl acetate bacteroides thetaiotaomicron 0.488 0.488 1 PMID:34074097 -3.1.1.72 4-nitrophenyl acetate evansstolkia leycettana 326.0 326.0 1 PMID:30694400 -3.1.1.72 4-nitrophenyl acetate flavobacterium johnsoniae 120.8 120.8 1 PMID:29588659 -3.1.1.72 4-nitrophenyl acetate irpex lacteus 29.1 29.1 1 PMID:34429691 -3.1.1.72 4-nitrophenyl acetate uncultured microorganism 293.3 293.3 1 PMID:27702488 -3.1.1.72 4-nitrophenyl butyrate bacteroides thetaiotaomicron 0.115 0.115 1 PMID:34074097 -3.1.1.72 4-yethylumbelliferyl acetate thermoanaerobacterium saccharolyticum 245.0 216.0 2 PMID:7574610 -3.1.1.72 p-nitrophenyl acetate thermobifida fusca 47.6 47.6 1 PMID:22578869 -3.1.1.73 1-naphthyl acetate thermochaetoides dissita 32.0 32.0 2 * -3.1.1.73 2-butyl ferulate fusarium oxysporum 1.24 1.24 1 PMID:18414848 -3.1.1.73 2-butyl ferulate talaromyces stipitatus 1345.0 1345.0 1 PMID:16584797 -3.1.1.73 2-o-[5-o-(trans-feruloyl)-beta-l-arabinofuranosyl]-d-xylopyranose pleurotus eryngii 3.41 3.41 1 PMID:30704902 -3.1.1.73 4-methylumbelliferyl p-trimethylammonio cinnamate pseudoalteromonas haloplanktis 11.9 11.9 1 PMID:17543477 -3.1.1.73 4-nitrophenyl 2-o-(e)-feruloyl-alpha-d-xylopyranoside aspergillus niger 1.17 1.17 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 2-o-(e)-feruloyl-alpha-d-xylopyranoside fusarium oxysporum 5.2 5.2 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 2-o-(e)-feruloyl-alpha-d-xylopyranoside talaromyces stipitatus 39.7 39.7 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 2-o-(e)-feruloyl-alpha-l-arabinofuranoside fusarium oxysporum 7.05 3.8 2 PMID:16901567 -3.1.1.73 4-nitrophenyl 2-o-(e)-feruloyl-alpha-l-arabinofuranoside talaromyces stipitatus 38.9 38.9 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 2-o-acetyl-alpha-l-arabinofuranoside aspergillus oryzae 0.15 0.15 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 2-o-acetyl-beta-d-xylopyranoside aspergillus oryzae 3.23 3.23 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 2-o-trans-feruloyl-alpha-l-arabinofuranoside aureobasidium pullulans 70.2 70.2 1 PMID:12957952 -3.1.1.73 4-nitrophenyl 2-o-trans-feruloyl-alpha-l-arabinofuranoside fusarium oxysporum 600.0 300.88 2 PMID:18414848 -3.1.1.73 4-nitrophenyl 2-o-trans-feruloyl-alpha-l-arabinofuranoside thermothelomyces heterothallicus 3.7 3.7 1 * -3.1.1.73 4-nitrophenyl 3-o-(e)-feruloyl-alpha-d-xylopyranoside aspergillus niger 0.7 0.7 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 3-o-(e)-feruloyl-alpha-d-xylopyranoside fusarium oxysporum 0.86 0.86 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 3-o-(e)-feruloyl-alpha-l-arabinofuranoside fusarium oxysporum 0.81 0.81 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 3-o-(e)-feruloyl-alpha-l-arabinofuranoside talaromyces stipitatus 34.2 34.2 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 3-o-acetyl-beta-d-xylopyranoside aspergillus oryzae 1.9 1.405 2 PMID:16901567 -3.1.1.73 4-nitrophenyl 3-o-acetyl-beta-d-xylopyranoside fusarium oxysporum 0.89 0.89 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 4-o-(e)-feruloyl-alpha-d-xylopyranoside aspergillus niger 0.24 0.24 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 4-o-(e)-feruloyl-alpha-d-xylopyranoside talaromyces stipitatus 17.9 17.9 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 5-o-(e)-feruloyl-alpha-l-arabinofuranoside aspergillus niger 175.0 175.0 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 5-o-(e)-feruloyl-alpha-l-arabinofuranoside fusarium oxysporum 3.66 3.1950000000000003 2 PMID:16901567 -3.1.1.73 4-nitrophenyl 5-o-(e)-feruloyl-alpha-l-arabinofuranoside talaromyces stipitatus 22.5 22.5 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 5-o-acetyl-alpha-l-arabinofuranoside aspergillus niger 2.33 2.33 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 5-o-acetyl-alpha-l-arabinofuranoside aspergillus oryzae 1.77 1.77 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 5-o-acetyl-alpha-l-arabinofuranoside fusarium oxysporum 6.37 6.37 1 PMID:16901567 -3.1.1.73 4-nitrophenyl 5-o-trans-feruloyl-alpha-l-arabinofuranoside aureobasidium pullulans 65.5 65.5 1 PMID:12957952 -3.1.1.73 4-nitrophenyl 5-o-trans-feruloyl-alpha-l-arabinofuranoside fusarium oxysporum 166.7 84.125 2 PMID:18414848 -3.1.1.73 4-nitrophenyl 5-o-trans-feruloyl-alpha-l-arabinofuranoside thermothelomyces heterothallicus 10.3 10.3 1 * -3.1.1.73 4-nitrophenyl acetate butyrivibrio proteoclasticus 23.0 23.0 1 PMID:30704902 -3.1.1.73 4-nitrophenyl acetate talaromyces pinophilus 15.3 15.3 1 * -3.1.1.73 4-nitrophenyl acetate thermochaetoides dissita 60.0 60.0 1 * -3.1.1.73 4-nitrophenyl acetate uncultured bacterium 63.2 63.2 1 PMID:21757926 -3.1.1.73 4-nitrophenyl butanoate thermochaetoides dissita 59.0 41.5 2 * -3.1.1.73 4-nitrophenyl butyrate butyrivibrio proteoclasticus 24.0 24.0 1 PMID:30704902 -3.1.1.73 4-nitrophenyl butyrate parageobacillus thermoglucosidasius 14793.0 14793.0 1 PMID:31201678 -3.1.1.73 4-nitrophenyl butyrate uncultured bacterium 203.2 203.2 1 PMID:21757926 -3.1.1.73 4-nitrophenyl caprate parageobacillus thermoglucosidasius 4579.0 4579.0 1 PMID:31201678 -3.1.1.73 4-nitrophenyl caprylate parageobacillus thermoglucosidasius 5491.0 5491.0 1 PMID:31201678 -3.1.1.73 4-nitrophenyl ferulate lentilactobacillus buchneri 6.7 6.7 1 PMID:36569051 -3.1.1.73 4-nitrophenyl ferulate talaromyces pinophilus 23.1 23.1 1 * -3.1.1.73 4-nitrophenyl ferulate thermochaetoides dissita 24.0 24.0 1 * -3.1.1.73 4-nitrophenyl ferulate uncultured bacterium 19.7 19.7 1 PMID:21757926 -3.1.1.73 4-nitrophenyl laurate parageobacillus thermoglucosidasius 3700.0 3700.0 1 PMID:31201678 -3.1.1.73 5-o-p-coumaroylquinic acid aspergillus niger 48.0 48.0 1 PMID:16697997 -3.1.1.73 alpha-naphthyl acetate pseudoalteromonas haloplanktis 2.75 2.75 1 PMID:17543477 -3.1.1.73 alpha-naphthyl propionate aspergillus oryzae 5.8 5.8 1 * -3.1.1.73 alpha-naphthylbutyrate aspergillus awamori 153.0 77.665 2 PMID:15716038;PMID:17031032 -3.1.1.73 alpha-naphthylcaprylate aspergillus awamori 0.85 0.85 1 PMID:15716038 -3.1.1.73 beta-d-xylopyranosyl-(1->2)-5-o-trans-feruloyl-l-arabinofuranose pleurotus sapidus 1.96 1.96 1 PMID:26272349 -3.1.1.73 beta-d-xylopyranosyl-(1->2)-5-o-trans-feruloyl-l-arabinofuranose rhizoctonia solani 29.1 29.1 1 PMID:28159727 -3.1.1.73 beta-naphthyl acetate pseudoalteromonas haloplanktis 1.8 1.8 1 PMID:17543477 -3.1.1.73 chlorogenate bacillus amyloliquefaciens 275.0 12.06 3 * -3.1.1.73 chlorogenate rhizoctonia solani 29.3 29.3 1 PMID:28159727 -3.1.1.73 chlorogenic acid aspergillus niger 63.0 63.0 1 PMID:16697997 -3.1.1.73 chlorogenic acid schizophyllum commune 7.5 7.05 2 * -3.1.1.73 coniferyl p-coumarate aspergillus niger 140.0 80.0 2 PMID:16697997 -3.1.1.73 ethyl ferulate acetivibrio thermocellus 5.7 5.7 1 PMID:27600375 -3.1.1.73 ethyl ferulate actinomyces sp. oral taxon 448 10.53 10.53 1 PMID:26497017 -3.1.1.73 ethyl ferulate alternaria tenuissima 25.9 25.9 1 * -3.1.1.73 ethyl ferulate aspergillus niger 29.4 29.4 1 PMID:27600375 -3.1.1.73 ethyl ferulate bacillus amyloliquefaciens 25.0 3.18 3 * -3.1.1.73 ethyl ferulate fusarium oxysporum 0.46 0.46 1 PMID:18414848 -3.1.1.73 ethyl ferulate rumen bacterium 30.7 30.7 1 PMID:27600375 -3.1.1.73 ethyl ferulate streptomyces cinnamoneus 0.0422 0.0422 1 PMID:29150515 -3.1.1.73 ethyl ferulate streptomyces sp. th-2 0.0027 0.0027 1 PMID:29150515 -3.1.1.73 ethyl ferulate talaromyces stipitatus 9570.0 9570.0 1 PMID:16584797 -3.1.1.73 ethyl ferulate thermobacillus xylanilyticus 35.4 35.4 1 PMID:36403470 -3.1.1.73 ethyl ferulate thermochaetoides dissita 4.1 4.1 2 * -3.1.1.73 ethyl ferulate thermothelomyces thermophilus 11.2 11.2 1 PMID:27600375 -3.1.1.73 ethyl ferulate uncultured microorganism 27.8 27.8 1 PMID:31102076 -3.1.1.73 ferulate aspergillus niger 62.0 62.0 1 PMID:20801026 -3.1.1.73 ferulic acid 4-nitrophenyl ester aspergillus usamii 135.0 135.0 1 PMID:25969986 -3.1.1.73 ferulic acid ethyl ester escherichia coli 0.9 0.9 1 PMID:26956238 -3.1.1.73 ferulic acid methyl ester aspergillus terreus 2.6 2.6 1 PMID:26282562 -3.1.1.73 ferulic acid methyl ester escherichia coli 1.5 1.5 1 PMID:26956238 -3.1.1.73 feruloyl arabino-xylo-oligosaccharides aspergillus nidulans 11.8 11.8 1 PMID:22770893 -3.1.1.73 iso-butyl ferulate fusarium oxysporum 0.95 0.95 1 PMID:18414848 -3.1.1.73 iso-butyl ferulate talaromyces stipitatus 2989.0 2989.0 1 PMID:16584797 -3.1.1.73 iso-propyl ferulate fusarium oxysporum 0.26 0.26 1 PMID:18414848 -3.1.1.73 iso-propyl ferulate talaromyces stipitatus 2645.0 2644.5 2 PMID:16584797 -3.1.1.73 methyl 2-hydroxy cinnamate talaromyces stipitatus 2.2 2.2 1 PMID:16584797 -3.1.1.73 methyl 3,4-dihydroxy cinnamate thermothelomyces heterothallicus 0.133 0.133 1 PMID:16584797 -3.1.1.73 methyl 3,4-dihydroxy-phenyl propionate talaromyces stipitatus 142.0 103.225 2 PMID:16584797 -3.1.1.73 methyl 3,4-dihydroxy-phenyl propionate thermothelomyces heterothallicus 0.183 0.183 1 PMID:16584797 -3.1.1.73 methyl 3,4-dimethoxy cinnamate talaromyces stipitatus 0.25 0.25 1 PMID:16584797 -3.1.1.73 methyl 3,4-dimethoxy cinnamate thermothelomyces heterothallicus 0.067 0.067 1 PMID:16584797 -3.1.1.73 methyl 3,5-dimethoxy cinnamate talaromyces stipitatus 0.1 0.1 1 PMID:16584797 -3.1.1.73 methyl 3-hydroxy cinnamate talaromyces stipitatus 24.1 24.1 1 PMID:16584797 -3.1.1.73 methyl 3-hydroxy cinnamate thermothelomyces heterothallicus 0.117 0.117 1 PMID:16584797 -3.1.1.73 methyl 3-hydroxy-4-methoxy cinnamate talaromyces stipitatus 0.7 0.7 1 PMID:16584797 -3.1.1.73 methyl 3-hydroxy-4-methoxy cinnamate thermothelomyces heterothallicus 0.05 0.05 1 PMID:16584797 -3.1.1.73 methyl 3-methoxy cinnamate talaromyces stipitatus 27.28 21.59 2 PMID:16584797 -3.1.1.73 methyl 3-methoxy cinnamate thermothelomyces heterothallicus 0.22 0.22 1 PMID:16584797 -3.1.1.73 methyl 4-coumarate aspergillus flavus 0.27 0.27 2 PMID:23981381;PMID:30704902 -3.1.1.73 methyl 4-coumarate aspergillus terreus 1.32 1.295 4 PMID:30704902 -3.1.1.73 methyl 4-coumarate aureobasidium pullulans 31.1 31.1 1 PMID:30704902 -3.1.1.73 methyl 4-coumarate bacillus pumilus 684.7 684.7 1 PMID:32531366 -3.1.1.73 methyl 4-coumarate cellulosilyticum ruminicola 538.6 310.5 3 PMID:30704902 -3.1.1.73 methyl 4-coumarate fusarium oxysporum 222.9 19.88 3 PMID:30704902 -3.1.1.73 methyl 4-coumarate neurospora crassa 12.19 12.19 1 PMID:30704902 -3.1.1.73 methyl 4-coumarate schizophyllum commune 105.1 98.25 2 PMID:30704902 -3.1.1.73 methyl 4-coumarate talaromyces stipitatus 9.55 9.55 1 PMID:30704902 -3.1.1.73 methyl 4-coumarate thermothelomyces thermophilus 5.47 3.0 2 PMID:30704902 -3.1.1.73 methyl 4-coumarate uncultured bacterium 7.5 7.5 1 PMID:21757926 -3.1.1.73 methyl 4-coumarate uncultured microorganism 23.25 23.25 1 PMID:31102076 -3.1.1.73 methyl 4-hydroxy cinnamate talaromyces stipitatus 9.55 9.55 1 PMID:16584797 -3.1.1.73 methyl 4-hydroxy cinnamate thermothelomyces heterothallicus 0.533 0.533 1 PMID:16584797 -3.1.1.73 methyl 4-hydroxy-3,5-dimethoxy cinnamate talaromyces stipitatus 9.3 9.3 1 PMID:16584797 -3.1.1.73 methyl 4-hydroxy-3,5-dimethoxy cinnamate thermothelomyces heterothallicus 0.4 0.4 1 PMID:16584797 -3.1.1.73 methyl 4-hydroxy-3-methoxy cinnamate talaromyces stipitatus 9.65 9.65 1 PMID:16584797 -3.1.1.73 methyl 4-hydroxy-3-methoxy cinnamate thermothelomyces heterothallicus 2.6 2.6 1 PMID:16584797 -3.1.1.73 methyl 4-hydroxy-3-methoxy phenyl propionate talaromyces stipitatus 125.9 125.9 1 PMID:16584797 -3.1.1.73 methyl 4-hydroxy-3-methoxy phenyl propionate thermothelomyces heterothallicus 0.87 0.87 1 PMID:16584797 -3.1.1.73 methyl 4-hydroxybenzoate schizophyllum commune 12.5 11.85 2 * -3.1.1.73 methyl caffeate actinomyces sp. 278.18 278.18 1 PMID:30704902 -3.1.1.73 methyl caffeate actinomyces sp. oral taxon 448 278.0 278.0 1 PMID:26497017 -3.1.1.73 methyl caffeate aspergillus niger 234.0 234.0 1 PMID:16697997 -3.1.1.73 methyl caffeate aspergillus ochraceus 2306.0 2306.0 1 * -3.1.1.73 methyl caffeate aureobasidium pullulans 30.0 30.0 2 PMID:12957952;PMID:30704902 -3.1.1.73 methyl caffeate bacillus pumilus 337.8 337.8 1 PMID:32531366 -3.1.1.73 methyl caffeate cellulosilyticum ruminicola 330.9 232.7 3 PMID:30704902 -3.1.1.73 methyl caffeate fusarium oxysporum 438.0 5.915 8 PMID:16702605;PMID:18414848;PMID:29795702;PMID:30704902 -3.1.1.73 methyl caffeate neurospora crassa 4.8 4.8 3 PMID:14661116;PMID:16702605;PMID:30704902 -3.1.1.73 methyl caffeate rhizoctonia solani 20.0 20.0 1 PMID:28159727 -3.1.1.73 methyl caffeate schizophyllum commune 38.4 36.25 4 PMID:30704902 -3.1.1.73 methyl caffeate talaromyces funiculosus 24.1 24.1 1 PMID:16702605 -3.1.1.73 methyl caffeate thermochaetoides dissita 3.1 3.1 2 * -3.1.1.73 methyl caffeate thermothelomyces heterothallicus 0.1 0.1 1 * -3.1.1.73 methyl caffeate thermothelomyces thermophilus 4.56 2.3449999999999998 2 PMID:30704902 -3.1.1.73 methyl caffeate uncultured microorganism 8.4 8.4 1 PMID:31102076 -3.1.1.73 methyl cinnamate talaromyces stipitatus 20.27 11.885 2 PMID:16584797 -3.1.1.73 methyl cinnamate thermothelomyces heterothallicus 0.05 0.05 1 PMID:16584797 -3.1.1.73 methyl coumarate fusarium oxysporum 19.88 13.0 3 PMID:16702605 -3.1.1.73 methyl coumarate neurospora crassa 12.19 6.3 2 PMID:16702605 -3.1.1.73 methyl coumarate talaromyces funiculosus 24.2 24.2 1 PMID:16702605 -3.1.1.73 methyl ferulate acetivibrio thermocellus 8.0 8.0 1 PMID:27600375 -3.1.1.73 methyl ferulate alternaria tenuissima 19.9 19.9 1 * -3.1.1.73 methyl ferulate aspergillus flavus 2.21 2.21 2 PMID:23981381;PMID:30704902 -3.1.1.73 methyl ferulate aspergillus nidulans 10.1 10.1 1 PMID:22770893 -3.1.1.73 methyl ferulate aspergillus niger 70.74 24.45 6 PMID:16128806;PMID:16697997;PMID:27600375;PMID:30704902 -3.1.1.73 methyl ferulate aspergillus ochraceus 3344.0 3344.0 1 * -3.1.1.73 methyl ferulate aspergillus terreus 2.59 2.59 1 PMID:30704902 -3.1.1.73 methyl ferulate aureobasidium pullulans 15.3 15.3 2 PMID:12957952;PMID:30704902 -3.1.1.73 methyl ferulate auricularia auricula-judae 1.4 1.4 1 PMID:30704902 -3.1.1.73 methyl ferulate bacillus amyloliquefaciens 12.0 8.6 3 * -3.1.1.73 methyl ferulate bacillus pumilus 575.0 575.0 1 PMID:32531366 -3.1.1.73 methyl ferulate bacteroides intestinalis 0.032 0.032 1 PMID:35316064 -3.1.1.73 methyl ferulate caldanaerobacter subterraneus subsp. tengcongensis 0.28 0.28 1 PMID:20127235 -3.1.1.73 methyl ferulate cellulosilyticum ruminicola 2130.9 645.9 3 PMID:30704902 -3.1.1.73 methyl ferulate fusarium oxysporum 232.0 6.875 8 PMID:16702605;PMID:18414848;PMID:29795702;PMID:30704902 -3.1.1.73 methyl ferulate lentilactobacillus buchneri 16.3 16.3 1 PMID:36569051 -3.1.1.73 methyl ferulate neurospora crassa 12.19 5.24 4 PMID:14661116;PMID:16702605;PMID:30704902 -3.1.1.73 methyl ferulate pleurotus eryngii 0.85 0.85 2 PMID:24607359;PMID:30704902 -3.1.1.73 methyl ferulate pleurotus sapidus 1.2 1.2 1 PMID:26272349 -3.1.1.73 methyl ferulate rumen bacterium 33.5 33.5 1 PMID:27600375 -3.1.1.73 methyl ferulate rumen microorganism 31.4 3.3049999999999997 4 PMID:29390959 -3.1.1.73 methyl ferulate schizophyllum commune 54.7 52.85 4 PMID:30704902 -3.1.1.73 methyl ferulate sorangium cellulosum 8.3 8.25 2 PMID:30704902 -3.1.1.73 methyl ferulate streptomyces cinnamoneus 0.0283 0.0283 1 PMID:29150515 -3.1.1.73 methyl ferulate streptomyces sp. th-2 0.0045 0.0045 1 PMID:29150515 -3.1.1.73 methyl ferulate streptomyces werraensis 1.98 1.98 1 PMID:30704902 -3.1.1.73 methyl ferulate talaromyces funiculosus 16.0 16.0 1 PMID:16702605 -3.1.1.73 methyl ferulate talaromyces pinophilus 20.9 20.9 1 * -3.1.1.73 methyl ferulate talaromyces stipitatus 10.0 9.65 3 PMID:12767807;PMID:16584797;PMID:30704902 -3.1.1.73 methyl ferulate thermothelomyces heterothallicus 2.6 2.6 1 * -3.1.1.73 methyl ferulate thermothelomyces thermophilus 8.8 3.3 3 PMID:27600375;PMID:30704902 -3.1.1.73 methyl ferulate uncultured bacterium 79.01 49.05500000000001 2 PMID:21757926;PMID:36981096 -3.1.1.73 methyl ferulate uncultured microorganism 36.9 28.25 2 PMID:29968147;PMID:31102076 -3.1.1.73 methyl p-coumarate alternaria tenuissima 7.5 7.5 1 * -3.1.1.73 methyl p-coumarate aspergillus niger 69.0 34.865 2 PMID:16128806;PMID:16697997 -3.1.1.73 methyl p-coumarate aspergillus ochraceus 2710.0 2710.0 1 * -3.1.1.73 methyl p-coumarate aureobasidium pullulans 31.1 31.1 1 PMID:12957952 -3.1.1.73 methyl p-coumarate bacillus amyloliquefaciens 43.88 8.9 3 * -3.1.1.73 methyl p-coumarate caldanaerobacter subterraneus subsp. tengcongensis 0.22 0.22 1 PMID:20127235 -3.1.1.73 methyl p-coumarate fusarium oxysporum 546.0 19.9 3 PMID:18414848;PMID:29795702 -3.1.1.73 methyl p-coumarate neurospora crassa 12.19 6.3 2 PMID:14661116 -3.1.1.73 methyl p-coumarate rhizoctonia solani 33.1 33.1 1 PMID:28159727 -3.1.1.73 methyl p-coumarate schizophyllum commune 105.1 98.25 2 * -3.1.1.73 methyl p-coumarate talaromyces stipitatus 9.55 9.55 1 PMID:12767807 -3.1.1.73 methyl p-coumarate thermochaetoides dissita 5.8 5.8 2 * -3.1.1.73 methyl p-coumarate thermothelomyces heterothallicus 0.5 0.5 1 * -3.1.1.73 methyl p-coumarate uncultured microorganism 6.1 6.1 1 PMID:29968147 -3.1.1.73 methyl sinapate alternaria tenuissima 1.0 1.0 1 * -3.1.1.73 methyl sinapate aspergillus flavus 0.9 0.9 1 PMID:30704902 -3.1.1.73 methyl sinapate aspergillus niger 84.95 84.95 1 PMID:30704902 -3.1.1.73 methyl sinapate aspergillus terreus 4.68 4.68 1 PMID:30704902 -3.1.1.73 methyl sinapate aureobasidium pullulans 3.7 3.7 1 PMID:30704902 -3.1.1.73 methyl sinapate bacillus pumilus 19.2 19.2 1 PMID:32531366 -3.1.1.73 methyl sinapate caldanaerobacter subterraneus subsp. tengcongensis 0.28 0.28 1 PMID:20127235 -3.1.1.73 methyl sinapate fusarium oxysporum 116.6 5.069999999999999 8 PMID:16702605;PMID:18414848;PMID:29795702;PMID:30704902 -3.1.1.73 methyl sinapate sorangium cellulosum 9.6 8.05 2 PMID:30704902 -3.1.1.73 methyl sinapate streptomyces werraensis 0.89 0.89 1 PMID:30704902 -3.1.1.73 methyl sinapate talaromyces stipitatus 9.26 9.26 1 PMID:30704902 -3.1.1.73 methyl sinapate thermothelomyces thermophilus 0.4 0.4 1 PMID:30704902 -3.1.1.73 methyl sinapate uncultured bacterium 16.2 16.2 1 PMID:21757926 -3.1.1.73 methyl sinapate uncultured microorganism 18.8 9.950000000000001 2 PMID:29968147;PMID:31102076 -3.1.1.73 methyl sinapinate aspergillus flavus 0.9 0.9 1 PMID:23981381 -3.1.1.73 methyl sinapinate aspergillus niger 84.95 61.0 3 PMID:16128806;PMID:16697997 -3.1.1.73 methyl sinapinate aspergillus ochraceus 2306.0 2306.0 1 * -3.1.1.73 methyl sinapinate aureobasidium pullulans 3.7 3.7 1 PMID:12957952 -3.1.1.73 methyl sinapinate fusarium oxysporum 0.5 0.5 1 * -3.1.1.73 methyl sinapinate streptomyces cinnamoneus 0.0017 0.0017 1 PMID:29150515 -3.1.1.73 methyl sinapinate streptomyces sp. th-2 0.0008 0.0008 1 PMID:29150515 -3.1.1.73 methyl sinapinate talaromyces stipitatus 9.26 5.615 2 PMID:12767807 -3.1.1.73 methyl sinapinate thermothelomyces heterothallicus 0.4 0.4 1 * -3.1.1.73 methyl vanillate uncultured microorganism 2.7 2.7 1 PMID:31102076 -3.1.1.73 methylumbelliferyl acetate pseudoalteromonas haloplanktis 0.1 0.1 1 PMID:17543477 -3.1.1.73 n-butyl ferulate fusarium oxysporum 14.05 14.05 1 PMID:18414848 -3.1.1.73 n-butyl ferulate talaromyces stipitatus 3378.0 3378.0 1 PMID:16584797 -3.1.1.73 n-decyl ferulate acetivibrio thermocellus 0.4 0.4 1 PMID:27600375 -3.1.1.73 n-decyl ferulate aspergillus niger 4.6 4.6 1 PMID:27600375 -3.1.1.73 n-decyl ferulate rumen bacterium 2.6 2.6 1 PMID:27600375 -3.1.1.73 n-hexyl ferulate acetivibrio thermocellus 0.2 0.2 1 PMID:27600375 -3.1.1.73 n-hexyl ferulate aspergillus niger 9.8 9.8 1 PMID:27600375 -3.1.1.73 n-hexyl ferulate rumen bacterium 6.1 6.1 1 PMID:27600375 -3.1.1.73 n-hexyl ferulate thermothelomyces thermophilus 8.9 8.9 1 PMID:27600375 -3.1.1.73 n-propyl ferulate acetivibrio thermocellus 3.2 3.2 1 PMID:27600375 -3.1.1.73 n-propyl ferulate aspergillus niger 44.6 44.6 1 PMID:27600375 -3.1.1.73 n-propyl ferulate fusarium oxysporum 0.18 0.18 1 PMID:18414848 -3.1.1.73 n-propyl ferulate rumen bacterium 31.7 31.7 1 PMID:27600375 -3.1.1.73 n-propyl ferulate talaromyces stipitatus 1358.0 1358.0 1 PMID:16584797 -3.1.1.73 n-propyl ferulate thermothelomyces thermophilus 12.1 12.1 1 PMID:27600375 -3.1.1.73 o-[2-o-(transferuloyl)-alpha-l-arabinofuranosyl]-(1,5)-l-arabinose neurospora crassa 6.04 6.04 1 PMID:16702605 -3.1.1.73 o-[5-o-(trans-feruloyl)-alpha-l-araf] aspergillus niger 121.0 64.5 2 PMID:16697997 -3.1.1.73 o-[5-o-(trans-feruloyl)-alpha-l-araf]-(1,3)d-xylp aspergillus niger 95.0 51.5 2 PMID:16697997 -3.1.1.73 p-coumaric acid methyl ester aspergillus terreus 0.31 0.31 1 PMID:26282562 -3.1.1.73 p-coumaric acid methyl ester escherichia coli 8.1 8.1 1 PMID:26956238 -3.1.1.73 p-nitrophenyl acetate butyrivibrio proteoclasticus 0.19 0.19 1 PMID:20058325 -3.1.1.73 p-nitrophenyl acetate pseudoalteromonas haloplanktis 2.0 2.0 1 PMID:17543477 -3.1.1.73 p-nitrophenyl butyrate butyrivibrio proteoclasticus 0.24 0.24 1 PMID:20058325 -3.1.1.73 sinapic acid methyl ester aspergillus terreus 0.94 0.94 1 PMID:26282562 -3.1.1.74 4-nitrophenyl acetate aspergillus nidulans 40.3 40.3 1 PMID:28124733 -3.1.1.74 4-nitrophenyl acetate coprinopsis cinerea 41.37 41.37 1 PMID:34653507 -3.1.1.74 4-nitrophenyl acetate cryptococcus sp. s-2 29.74 29.74 1 PMID:34653507 -3.1.1.74 4-nitrophenyl acetate fusarium oxysporum 121.0 121.0 1 PMID:26291558 -3.1.1.74 4-nitrophenyl acetate fusarium solani 230.0 129.98 2 PMID:11004558;PMID:34653507 -3.1.1.74 4-nitrophenyl acetate marinactinospora thermotolerans 4.47 4.47 1 PMID:35557867 -3.1.1.74 4-nitrophenyl acetate pyrenopeziza brassicae 11.84 11.84 1 PMID:34653507 -3.1.1.74 4-nitrophenyl acetate thermobifida alba 2.72 2.72 1 PMID:24055682 -3.1.1.74 4-nitrophenyl acetate thermobifida cellulosilytica 436.0 117.0 8 PMID:23592055;PMID:24055682;PMID:25795674 -3.1.1.74 4-nitrophenyl acetate thermobifida fusca 39.5 39.5 1 PMID:24055682 -3.1.1.74 4-nitrophenyl acetate thermothielavioides terrestris 65.79 33.185 2 PMID:26041215;PMID:34653507 -3.1.1.74 4-nitrophenyl butanoate fusarium oxysporum 111.9 111.9 1 PMID:26291558 -3.1.1.74 4-nitrophenyl butanoate thermobifida cellulosilytica 325.0 99.0 4 PMID:25795674 -3.1.1.74 4-nitrophenyl butanoate thermothielavioides terrestris 0.85 0.85 1 PMID:26041215 -3.1.1.74 4-nitrophenyl butyrate alternaria brassicicola 0.022 0.022 1 PMID:21713515 -3.1.1.74 4-nitrophenyl butyrate aspergillus fumigatus 0.0845 0.0845 1 PMID:21713515 -3.1.1.74 4-nitrophenyl butyrate aspergillus oryzae 0.0163 0.0163 1 PMID:21713515 -3.1.1.74 4-nitrophenyl butyrate botrytis cinerea 303.03 303.03 1 * -3.1.1.74 4-nitrophenyl butyrate coprinopsis cinerea 8.96 8.96 1 PMID:34653507 -3.1.1.74 4-nitrophenyl butyrate cryptococcus sp. s-2 13.52 13.52 1 PMID:34653507 -3.1.1.74 4-nitrophenyl butyrate fusarium solani 7.7 3.8536 2 PMID:21713515;PMID:34653507 -3.1.1.74 4-nitrophenyl butyrate fusarium vanettenii 837.0 837.0 1 * -3.1.1.74 4-nitrophenyl butyrate marinactinospora thermotolerans 14.1 14.1 1 PMID:35557867 -3.1.1.74 4-nitrophenyl butyrate mycothermus thermophilus 191.0 95.536 2 PMID:21713515;PMID:22579385 -3.1.1.74 4-nitrophenyl butyrate pyrenopeziza brassicae 6.45 6.45 1 PMID:34653507 -3.1.1.74 4-nitrophenyl butyrate thermobifida cellulosilytica 327.0 171.5 2 PMID:23592055 -3.1.1.74 4-nitrophenyl butyrate thermobifida fusca 742.0 612.5 2 * -3.1.1.74 4-nitrophenyl butyrate thermothielavioides terrestris 15.92 15.92 1 PMID:34653507 -3.1.1.74 4-nitrophenyl butyrate uncultured bacterium 359.0 298.0 6 PMID:24593046 -3.1.1.74 4-nitrophenyl caproate thermothielavioides terrestris 0.61 0.61 1 PMID:26041215 -3.1.1.74 4-nitrophenyl decanoate marinactinospora thermotolerans 69.85 69.85 1 PMID:35557867 -3.1.1.74 4-nitrophenyl dodecanoate coprinopsis cinerea 0.22 0.22 1 PMID:34653507 -3.1.1.74 4-nitrophenyl dodecanoate cryptococcus sp. s-2 3.49 3.49 1 PMID:34653507 -3.1.1.74 4-nitrophenyl dodecanoate fusarium solani 1.22 1.22 1 PMID:34653507 -3.1.1.74 4-nitrophenyl dodecanoate marinactinospora thermotolerans 30.52 30.52 1 PMID:35557867 -3.1.1.74 4-nitrophenyl dodecanoate pyrenopeziza brassicae 0.2 0.2 1 PMID:34653507 -3.1.1.74 4-nitrophenyl dodecanoate thermothielavioides terrestris 0.07 0.07 1 PMID:34653507 -3.1.1.74 4-nitrophenyl hexadecanoate coprinopsis cinerea 0.06 0.06 1 PMID:34653507 -3.1.1.74 4-nitrophenyl hexadecanoate cryptococcus sp. s-2 3.38 3.38 1 PMID:34653507 -3.1.1.74 4-nitrophenyl hexadecanoate fusarium solani 0.15 0.15 1 PMID:34653507 -3.1.1.74 4-nitrophenyl hexadecanoate pyrenopeziza brassicae 0.08 0.08 1 PMID:34653507 -3.1.1.74 4-nitrophenyl hexadecanoate thermothielavioides terrestris 0.09 0.09 1 PMID:34653507 -3.1.1.74 4-nitrophenyl hexanoate marinactinospora thermotolerans 41.72 41.72 1 PMID:35557867 -3.1.1.74 4-nitrophenyl laurate fusarium oxysporum 8.3 8.3 1 PMID:26291558 -3.1.1.74 4-nitrophenyl myristate marinactinospora thermotolerans 9.87 9.87 1 PMID:35557867 -3.1.1.74 4-nitrophenyl octadecanoate marinactinospora thermotolerans 14.31 14.31 1 PMID:35557867 -3.1.1.74 4-nitrophenyl octanoate coprinopsis cinerea 1.7 1.7 1 PMID:34653507 -3.1.1.74 4-nitrophenyl octanoate cryptococcus sp. s-2 3.81 3.81 1 PMID:34653507 -3.1.1.74 4-nitrophenyl octanoate fusarium solani 6.69 6.69 1 PMID:34653507 -3.1.1.74 4-nitrophenyl octanoate marinactinospora thermotolerans 79.39 79.39 1 PMID:35557867 -3.1.1.74 4-nitrophenyl octanoate mycothermus thermophilus 187.0 187.0 1 PMID:22579385 -3.1.1.74 4-nitrophenyl octanoate pyrenopeziza brassicae 1.43 1.43 1 PMID:34653507 -3.1.1.74 4-nitrophenyl octanoate thermothielavioides terrestris 2.3 2.3 1 PMID:34653507 -3.1.1.74 4-nitrophenyl palmitate marinactinospora thermotolerans 4.79 4.79 1 PMID:35557867 -3.1.1.74 4-nitrophenyl palmitate mycothermus thermophilus 18.0 18.0 1 PMID:22579385 -3.1.1.74 p-nitrophenyl butyrate fusarium solani 17400.0 15500.0 5 PMID:18501723 -3.1.1.74 p-nitrophenylbutanoate fusarium solani 539.0 539.0 1 PMID:11004558 -3.1.1.74 p-nitrophenylbutanoate monilinia fructicola 0.66 0.66 1 PMID:11929215 -3.1.1.74 tributyrin mycothermus thermophilus 238.0 238.0 1 PMID:22579385 -3.1.1.74 tricaprylin mycothermus thermophilus 509.0 509.0 1 PMID:22579385 -3.1.1.74 triolein mycothermus thermophilus 172.0 172.0 1 PMID:22579385 -3.1.1.75 poly((r)-3-hydroxybutyrate-co-(r)-3-hydroxyhexanoate) lihuaxuella thermophila 1.1 1.1 1 PMID:36222314 -3.1.1.75 poly((r)-3-hydroxybutyrate-co-(r)-3-hydroxyvalerate-co-(r)-3-hydroxyhexanoate) lihuaxuella thermophila 0.2 0.2 1 PMID:36222314 -3.1.1.75 poly((r)-3-hydroxybutyric acid) lihuaxuella thermophila 3.2 3.2 1 PMID:36222314 -3.1.1.79 2-naphthyl acetate bjerkandera adusta 5310.0 5310.0 1 PMID:28251842 -3.1.1.79 4-nitrophenyl acetate falsihalocynthiibacter arcticus 23.02 23.02 1 PMID:31694309 -3.1.1.79 4-nitrophenyl acetate mycobacterium marinum 94.0 94.0 1 PMID:37065048 -3.1.1.79 4-nitrophenyl acetate salinisphaera sp. p7-4 7.04 7.04 1 PMID:30653961 -3.1.1.79 4-nitrophenyl acetate uncultured bacterium 3160.0 3160.0 1 PMID:27328716 -3.1.1.79 4-nitrophenyl butyrate falsihalocynthiibacter arcticus 3.32 3.32 1 PMID:31694309 -3.1.1.79 4-nitrophenyl butyrate mycobacterium marinum 190.0 190.0 1 PMID:37065048 -3.1.1.79 4-nitrophenyl butyrate salinisphaera sp. p7-4 3.86 3.86 1 PMID:30653961 -3.1.1.79 4-nitrophenyl hexanoate falsihalocynthiibacter arcticus 0.2 0.2 1 PMID:31694309 -3.1.1.79 4-nitrophenyl hexanoate salinisphaera sp. p7-4 26.3 26.3 1 PMID:30653961 -3.1.1.79 4-nitrophenyl myristate mycobacterium marinum 0.28 0.28 1 PMID:37065048 -3.1.1.79 4-nitrophenyl octanoate mycobacterium marinum 1.1 1.1 1 PMID:37065048 -3.1.1.79 4-nitrophenyl palmitate halalkalibacterium halodurans 15260.0 13095.0 2 PMID:28710671 -3.1.1.79 4-nitrophenyl valerate mycobacterium marinum 15.0 15.0 1 PMID:37065048 -3.1.1.79 [(3-oxo-3h-spiro[[2]benzofuran-1,9'-xanthene]-3',6'-diyl)bis[(oxy)methylene] bis(3,3,3-trifluoropropanoate) mycobacterium marinum 0.013 0.013 1 PMID:37065048 -3.1.1.79 fluorescein bis((((1-(2-pyridinyl))cyclopropyl)carboxymethyl ether) mycobacterium marinum 0.00026 0.00026 1 PMID:37065048 -3.1.1.79 fluorescein bis(((1-cyano)cyclopropyl)carboxymethyl ether) mycobacterium marinum 0.0012 0.0012 1 PMID:37065048 -3.1.1.79 fluorescein bis(((1-hydroxy)cyclopropyl)carboxymethyl ether) mycobacterium marinum 0.0029 0.0029 1 PMID:37065048 -3.1.1.79 fluorescein bis(((1-methanesulfonyl)cyclopropyl)carboxymethyl ether) mycobacterium marinum 1.4e-05 1.4e-05 1 PMID:37065048 -3.1.1.79 fluorescein bis(((1-phenyl)cyclopropyl)carboxymethyl ether) mycobacterium marinum 0.00058 0.00058 1 PMID:37065048 -3.1.1.79 fluorescein bis(((1-trifluoromethyl)cyclopropyl)carboxymethyl ether) mycobacterium marinum 3.7e-05 3.7e-05 1 PMID:37065048 -3.1.1.79 fluorescein bis(((2,2-dichloro-1-methyl)cyclopropyl)carboxymethyl ether) mycobacterium marinum 0.00011 0.00011 1 PMID:37065048 -3.1.1.79 fluorescein bis(((2,2-dimethyl)cyclopropyl)carboxymethyl ether) mycobacterium marinum 0.0011 0.0011 1 PMID:37065048 -3.1.1.79 fluorescein bis((2-methyl)propionyloxymethyl ether) mycobacterium marinum 0.017 0.017 1 PMID:37065048 -3.1.1.79 fluorescein bis((3-methyl)propargyloxymethyl ether) mycobacterium marinum 0.0061 0.0061 1 PMID:37065048 -3.1.1.79 fluorescein bis((5-oxazolyl)carboxymethyl ether) mycobacterium marinum 0.003 0.003 1 PMID:37065048 -3.1.1.79 fluorescein bis(crotonyloxymethyl ether) mycobacterium marinum 0.0029 0.0029 1 PMID:37065048 -3.1.1.79 fluorescein bis(cyclopropyl)carboxymethyl ether) mycobacterium marinum 0.0009 0.0009 1 PMID:37065048 -3.1.1.79 fluorescein bis[(oxy)methylene] bis(2,2-dimethylpropanoate) mycobacterium marinum 2.4e-05 2.4e-05 1 PMID:37065048 -3.1.1.79 fluorescein bis[(oxy)methylene] bis(2-methylprop-2-enoate) mycobacterium marinum 0.02 0.02 1 PMID:37065048 -3.1.1.79 fluorescein bis[(oxy)methylene] bis(cyanoacetate) mycobacterium marinum 0.015 0.015 1 PMID:37065048 -3.1.1.79 fluorescein bis[(oxy)methylene] bis(pentafluorobenzoate) mycobacterium marinum 0.00023 0.00023 1 PMID:37065048 -3.1.1.79 fluorescein bis[(oxy)methylene] bis[(2-methoxyethoxy)acetate] mycobacterium marinum 0.12 0.12 1 PMID:37065048 -3.1.1.79 fluorescein bis[(oxy)methylene] di(2,5,8,11-tetraoxatetradecan-14-oate) mycobacterium marinum 0.0005 0.0005 1 PMID:37065048 -3.1.1.79 fluorescein bis[(oxy)methylene] dibenzoate mycobacterium marinum 0.0003 0.0003 1 PMID:37065048 -3.1.1.79 fluorescein bis[(oxy)methylene] dicyclobutanecarboxylate mycobacterium marinum 0.025 0.025 1 PMID:37065048 -3.1.1.79 fluorescein bis[(oxy)methylene] dicyclohexanecarboxylate mycobacterium marinum 0.0007 0.0007 1 PMID:37065048 -3.1.1.79 fluorescein bis[(oxy)methylene] dicyclopentanecarboxylate mycobacterium marinum 0.0012 0.0012 1 PMID:37065048 -3.1.1.79 fluorescein bis[(oxy)methylene] difuran-2-carboxylate mycobacterium marinum 0.003 0.003 1 PMID:37065048 -3.1.1.79 fluorescein bis[(oxy)methylene] diprop-2-enoate mycobacterium marinum 0.0093 0.0093 1 PMID:37065048 -3.1.1.79 fluorescein di(3-methoxy)propanoyloxymethyl ether mycobacterium marinum 0.093 0.093 1 PMID:37065048 -3.1.1.79 fluorescein di(methoxy)acetoxymethyl ether mycobacterium marinum 0.11 0.11 1 PMID:37065048 -3.1.1.79 fluorescein diacetoxymethyl ether mycobacterium marinum 0.1 0.1 1 PMID:37065048 -3.1.1.79 fluorescein dibutanoyloxymethyl ether mycobacterium marinum 0.062 0.062 1 PMID:37065048 -3.1.1.79 fluorescein dihexanoyloxymethyl ether mycobacterium marinum 0.0074 0.0074 1 PMID:37065048 -3.1.1.79 fluorescein dipentanoyloxymethyl ether mycobacterium marinum 0.024 0.024 1 PMID:37065048 -3.1.1.79 fluorescein dipropanoyloxymethyl ether mycobacterium marinum 0.18 0.18 1 PMID:37065048 -3.1.1.79 p-nitrophenyl butyrate homo sapiens 190.0 190.0 1 PMID:16325466 -3.1.1.79 p-nitrophenyl hexanoate saccharolobus solfataricus 34.5 18.5 2 PMID:17350931 -3.1.1.79 tributyrin homo sapiens 18.0 18.0 1 PMID:16325466 -3.1.1.79 tricaproyl glycerol halalkalibacterium halodurans 2763.0 2763.0 1 PMID:28710671 -3.1.1.79 trioctanoin homo sapiens 6.0 6.0 1 PMID:16325466 -3.1.1.79 trioleoyl glycerol halalkalibacterium halodurans 5280.0 5280.0 1 PMID:28710671 -3.1.1.79 tripalmitoyl glycerol halalkalibacterium halodurans 3078.0 3078.0 1 PMID:28710671 -3.1.1.79 tripropionin homo sapiens 7.0 7.0 1 PMID:16325466 -3.1.1.79 vinyl acetate homo sapiens 170.0 170.0 1 PMID:16325466 -3.1.1.79 vinyl butyrate homo sapiens 625.0 625.0 1 PMID:16325466 -3.1.1.79 vinyl laurate homo sapiens 375.0 375.0 1 PMID:16325466 -3.1.1.79 vinyl propionate homo sapiens 800.0 800.0 1 PMID:16325466 -3.1.1.8 (+)-cocaine homo sapiens 0.0085 0.0085 1 PMID:11104759 -3.1.1.8 (-)-cocaine homo sapiens 0.068 0.068 3 PMID:11104759;PMID:12130672;PMID:30080993 -3.1.1.8 (r)-3-benzoyloxy-1-benzylquinuclidinium bromide equus caballus 97.0 97.0 1 * -3.1.1.8 (r)-3-benzoyloxy-1-methylquinuclidinium iodide equus caballus 227.0 227.0 1 * -3.1.1.8 (s)-3-benzoyloxy-1-methylquinuclidinium iodide equus caballus 3.2 3.2 1 * -3.1.1.8 2-nitrophenyl butyrate homo sapiens 600.0 600.0 1 PMID:11341926 -3.1.1.8 6-monoacetylmorphine homo sapiens 0.0042 0.0042 1 PMID:30080993 -3.1.1.8 acetylcholine homo sapiens 1433.0 1433.0 1 PMID:20971807 -3.1.1.8 acetylthiocholine equus caballus 1020.0 726.55 2 PMID:23279886;PMID:5009701 -3.1.1.8 acetylthiocholine homo sapiens 336.7 334.9 3 PMID:20060817;PMID:28322391;PMID:29908755 -3.1.1.8 acetylthiocholine rattus norvegicus 23.5 11.7525 2 PMID:15106880 -3.1.1.8 acetylthiocholine sus scrofa 5.6 5.6 1 PMID:29908755 -3.1.1.8 bche-fp homo sapiens 1.75 1.75 1 PMID:28322391 -3.1.1.8 benzoylcholine homo sapiens 250.0 243.5 4 PMID:10646540;PMID:14686935;PMID:15128307;PMID:618874 -3.1.1.8 benzoylcholine rattus norvegicus 16.8 16.8 1 PMID:15106880 -3.1.1.8 benzoylthiocholine homo sapiens 13.3 7.0600000000000005 2 PMID:14686935;PMID:15128307 -3.1.1.8 butyrylcholine equus caballus 2850.0 2850.0 1 PMID:5009701 -3.1.1.8 butyrylthiocholine homo sapiens 565.0 450.0 7 PMID:10646540;PMID:11341926;PMID:12605682;PMID:18300943;PMID:20060817;PMID:29908755 -3.1.1.8 butyrylthiocholine oryza sativa 2066.7 2066.7 1 PMID:29411865 -3.1.1.8 butyrylthiocholine sus scrofa 4.78 4.78 1 PMID:29908755 -3.1.1.8 cocaine homo sapiens 418.3 418.3 1 PMID:18514178 -3.1.1.8 heroin homo sapiens 30.67 30.67 1 PMID:30080993 -3.1.1.8 n-methyl-(7-dimethylcarbamoxy)quinolinium iodide homo sapiens 4.17e-05 4.17e-05 1 PMID:618874 -3.1.1.8 n-methylindoxyl acetate homo sapiens 300.0 300.0 1 PMID:12044901 -3.1.1.8 o-nitrophenylbutyrate homo sapiens 800.0 800.0 1 PMID:618874 -3.1.1.8 propionylthiocholine homo sapiens 53.3 53.3 1 PMID:29908755 -3.1.1.8 propionylthiocholine rattus norvegicus 3350.0 1699.6 2 PMID:12110369;PMID:15106880 -3.1.1.8 succinylthiocholine homo sapiens 6.0 6.0 1 PMID:11341926 -3.1.1.81 (r)-gamma-caprolactone vulcanisaeta moutnovskia 3.04 3.04 1 PMID:25670483 -3.1.1.81 (s)-gamma-caprolactone vulcanisaeta moutnovskia 1.89 1.89 1 PMID:25670483 -3.1.1.81 3-oxo-dodecanoyl-l-homoserine lactone alicyclobacillus acidoterrestris 4.9 4.9 1 PMID:30050039 -3.1.1.81 delta-decalactone alicyclobacillus acidoterrestris 8.4 8.4 2 PMID:30050039 -3.1.1.81 delta-decalactone saccharococcus caldoxylosilyticus 4.1 4.1 1 PMID:30864300 -3.1.1.81 delta-nonalactone geobacillus kaustophilus 29.0 29.0 2 PMID:20980257 -3.1.1.81 delta-nonalactone saccharococcus caldoxylosilyticus 2.01 2.01 1 PMID:30864300 -3.1.1.81 delta-octanolactone saccharococcus caldoxylosilyticus 12.58 12.58 1 PMID:30864300 -3.1.1.81 delta-valerolactone alicyclobacillus acidoterrestris 8.4 8.4 2 PMID:30050039 -3.1.1.81 delta-valerolactone saccharococcus caldoxylosilyticus 1.24 1.24 1 PMID:30864300 -3.1.1.81 dodecanoic-delta-lactone vulcanisaeta moutnovskia 28.08 28.08 1 PMID:25670483 -3.1.1.81 dodecanoic-gamma-lactone vulcanisaeta moutnovskia 0.16 0.16 1 PMID:25670483 -3.1.1.81 epsilon-caprolactone saccharococcus caldoxylosilyticus 10.81 10.81 1 PMID:30864300 -3.1.1.81 epsilon-decalactone saccharococcus caldoxylosilyticus 1.09 1.09 1 PMID:30864300 -3.1.1.81 gamma-butyrolactone alicyclobacillus acidoterrestris 23.5 23.5 2 PMID:30050039 -3.1.1.81 gamma-butyrolactone saccharococcus caldoxylosilyticus 2.49 2.49 1 PMID:30864300 -3.1.1.81 gamma-decanolactone saccharococcus caldoxylosilyticus 2.69 2.69 1 PMID:30864300 -3.1.1.81 gamma-heptalactone saccharococcus caldoxylosilyticus 1.77 1.77 1 PMID:30864300 -3.1.1.81 gamma-heptanolide alicyclobacillus acidoterrestris 7.0 7.0 2 PMID:30050039 -3.1.1.81 gamma-nonalactone geobacillus kaustophilus 2.9 2.9 2 PMID:20980257 -3.1.1.81 gamma-nonalactone saccharococcus caldoxylosilyticus 20.5 20.5 1 PMID:30864300 -3.1.1.81 heptanoic-gamma-lactone vulcanisaeta moutnovskia 27.25 27.25 1 PMID:25670483 -3.1.1.81 l-homoserine lactone brevundimonas diminuta 4.69 4.69 1 PMID:24057406 -3.1.1.81 n-(3-oxodecanoyl)-l-homoserine lactone saccharolobus solfataricus 4.52 3.01 2 PMID:21183649;PMID:35324218 -3.1.1.81 n-(3-oxodecyl)-l-homoserine lactone brevundimonas diminuta 2.67 2.67 1 PMID:24057406 -3.1.1.81 n-(3-oxododecanoyl)-l-homoserine lactone bacillus thuringiensis 1.96 1.96 1 PMID:31082528 -3.1.1.81 n-(3-oxododecanoyl)-l-homoserine lactone saccharococcus caldoxylosilyticus 10.0 10.0 2 PMID:31993034;PMID:32390993 -3.1.1.81 n-(3-oxododecanoyl)-l-homoserine lactone saccharolobus solfataricus 1.8 1.01 3 PMID:21183649;PMID:31993034;PMID:35324218 -3.1.1.81 n-(3-oxododecyl)-l-homoserine lactone brevundimonas diminuta 1.83 1.83 1 PMID:24057406 -3.1.1.81 n-(3-oxohexanoyl)-l-homoserine lactone saccharolobus solfataricus 0.52 0.52 1 PMID:21183649 -3.1.1.81 n-(3-oxooctanoyl)-l-homoserine lactone geobacillus kaustophilus 0.29 0.29 1 PMID:20980257 -3.1.1.81 n-(3-oxooctanoyl)-l-homoserine lactone saccharococcus caldoxylosilyticus 9.48 9.48 1 PMID:30864300 -3.1.1.81 n-(3-oxooctanoyl)-l-homoserine lactone saccharolobus solfataricus 1.0 1.0 1 PMID:21183649 -3.1.1.81 n-(3-oxooctanoyl)-l-homoserine lactone salinicola salarius 214.8 118.185 2 PMID:35883097 -3.1.1.81 n-(3-oxooctyl)-l-homoserine lactone brevundimonas diminuta 4.66 4.66 1 PMID:24057406 -3.1.1.81 n-3-hydroxybutanoyl-l-homoserine lactone bacillus sp. (in: firmicutes) 29.3 29.3 1 PMID:14734559 -3.1.1.81 n-3-oxo-decanoyl-dl-homoserine lactone vulcanisaeta moutnovskia 0.47 0.47 1 PMID:25670483 -3.1.1.81 n-3-oxo-octanoyl-dl-homoserine lactone vulcanisaeta moutnovskia 0.35 0.35 1 PMID:25670483 -3.1.1.81 n-3-oxo-octanoyl-l-homoserine lactone geobacillus kaustophilus 0.29 0.29 1 PMID:20980257 -3.1.1.81 n-3-oxobutanoyl-l-homoserine lactone bacillus sp. (in: firmicutes) 28.6 28.6 1 PMID:14734559 -3.1.1.81 n-3-oxodecanoyl-l-homoserine lactone bacillus sp. (in: firmicutes) 20.2 20.2 1 PMID:14734559 -3.1.1.81 n-3-oxododecanoyl-l-homoserine lactone alicyclobacillus acidoterrestris 5.03 4.965 2 PMID:28777091;PMID:30050039 -3.1.1.81 n-3-oxododecanoyl-l-homoserine lactone enterobacter sp. cs66 101.5 101.5 1 PMID:29518220 -3.1.1.81 n-3-oxododecanoyl-l-homoserine lactone flagellimonas olearia 224.0 224.0 1 PMID:25398866 -3.1.1.81 n-3-oxododecanoyl-l-homoserine lactone saccharococcus caldoxylosilyticus 9.48 9.48 1 PMID:27599858 -3.1.1.81 n-3-oxohexanoyl-l-homoserine lactone bacillus sp. (in: firmicutes) 22.7 22.7 1 PMID:14734559 -3.1.1.81 n-3-oxohexanoyl-l-homoserine lactone flagellimonas olearia 293.0 293.0 1 PMID:25398866 -3.1.1.81 n-3-oxohexanoyl-l-homoserine lactone kurthia huakuii 0.168 0.168 1 PMID:29662232 -3.1.1.81 n-3-oxooctanoyl-l-homoserine lactone bacillus sp. (in: firmicutes) 22.2 22.2 1 PMID:14734559 -3.1.1.81 n-3-oxooctanoyl-l-homoserine lactone chryseobacterium sp. strb126 8.0 8.0 1 PMID:26115006 -3.1.1.81 n-3-oxooctanoyl-l-homoserine lactone flagellimonas olearia 218.0 218.0 1 PMID:25398866 -3.1.1.81 n-butanoyl-dl-homoserine lactone bacillus thuringiensis 0.00549 0.00549 1 PMID:24233057 -3.1.1.81 n-butanoyl-l-homoserine lactone alicyclobacillus acidoterrestris 13.54 13.54 1 PMID:28777091 -3.1.1.81 n-butanoyl-l-homoserine lactone bacillus sp. (in: firmicutes) 37.6 37.6 1 PMID:14734559 -3.1.1.81 n-butanoyl-l-homoserine lactone enterobacter sp. cs66 61.14 61.14 1 PMID:29518220 -3.1.1.81 n-butyryl-dl-homoserine lactone brevundimonas diminuta 2.62 2.62 1 PMID:24057406 -3.1.1.81 n-butyryl-l-homoserine lactone alicyclobacillus acidoterrestris 12.6 12.6 2 PMID:30050039 -3.1.1.81 n-butyryl-l-homoserine lactone bacillus thuringiensis 0.98 0.98 1 PMID:31082528 -3.1.1.81 n-butyryl-l-homoserine lactone bacillus thuringiensis serovar kurstaki 121.0 121.0 1 PMID:25547834 -3.1.1.81 n-butyryl-l-homoserine lactone chryseobacterium sp. strb126 39.0 39.0 1 PMID:26115006 -3.1.1.81 n-butyryl-l-homoserine lactone flagellimonas olearia 135.0 135.0 1 PMID:25398866 -3.1.1.81 n-butyryl-l-homoserine lactone saccharococcus caldoxylosilyticus 43.0 19.06 4 PMID:27599858;PMID:30864300;PMID:31993034;PMID:32390993 -3.1.1.81 n-butyryl-l-homoserine lactone saccharolobus solfataricus 0.37 0.37 1 PMID:31993034 -3.1.1.81 n-decanoyl-l-homoserine lactone alicyclobacillus acidoterrestris 5.2 5.2 3 PMID:28777091;PMID:30050039 -3.1.1.81 n-decanoyl-l-homoserine lactone bacillus thuringiensis 54.0 54.0 1 PMID:23387521 -3.1.1.81 n-decanoyl-l-homoserine lactone bacillus thuringiensis serovar kurstaki 89.0 89.0 1 PMID:25547834 -3.1.1.81 n-decanoyl-l-homoserine lactone chryseobacterium sp. strb126 5.2 5.2 1 PMID:26115006 -3.1.1.81 n-decanoyl-l-homoserine lactone enterobacter sp. cs66 98.31 98.31 1 PMID:29518220 -3.1.1.81 n-decanoyl-l-homoserine lactone kurthia huakuii 1.321 1.321 1 PMID:29662232 -3.1.1.81 n-decanoyl-l-homoserine lactone saccharococcus caldoxylosilyticus 5.48 5.48 2 PMID:27599858;PMID:30864300 -3.1.1.81 n-dodecanoyl-l-homoserine lactone chryseobacterium sp. strb126 0.4 0.4 1 PMID:26115006 -3.1.1.81 n-heptanoyl-dl-homoserine lactone bacillus thuringiensis 0.0235 0.0235 1 PMID:24233057 -3.1.1.81 n-heptanoyl-l-homoserine lactone bacillus thuringiensis 34.0 34.0 1 PMID:23387521 -3.1.1.81 n-heptanoyl-l-homoserine lactone chryseobacterium sp. strb126 80.0 80.0 1 PMID:26115006 -3.1.1.81 n-hexanoyl-(s)-homoserine lactone bacillus thuringiensis serovar kurstaki 117.0 117.0 1 PMID:15895999 -3.1.1.81 n-hexanoyl-dl-homoserine lactone bacillus thuringiensis 0.0102 0.0102 1 PMID:24233057 -3.1.1.81 n-hexanoyl-l-homoserine lactone alicyclobacillus acidoterrestris 14.0 14.0 3 PMID:28777091;PMID:30050039 -3.1.1.81 n-hexanoyl-l-homoserine lactone bacillus sp. (in: firmicutes) 35.7 35.7 1 PMID:14734559 -3.1.1.81 n-hexanoyl-l-homoserine lactone bacillus thuringiensis 510.0 210.5 6 PMID:21031319;PMID:23387521;PMID:31082528 -3.1.1.81 n-hexanoyl-l-homoserine lactone chryseobacterium sp. strb126 59.0 59.0 1 PMID:26115006 -3.1.1.81 n-hexanoyl-l-homoserine lactone enterobacter sp. cs66 69.43 69.43 1 PMID:29518220 -3.1.1.81 n-hexanoyl-l-homoserine lactone flagellimonas olearia 226.0 226.0 1 PMID:25398866 -3.1.1.81 n-hexanoyl-l-homoserine lactone geobacillus kaustophilus 0.17 0.17 2 PMID:20980257 -3.1.1.81 n-hexanoyl-l-homoserine lactone kurthia huakuii 0.649 0.649 1 PMID:29662232 -3.1.1.81 n-hexanoyl-l-homoserine lactone saccharococcus caldoxylosilyticus 8.95 8.95 2 PMID:27599858;PMID:30864300 -3.1.1.81 n-hexyl-l-homoserine lactone brevundimonas diminuta 3.17 3.17 1 PMID:24057406 -3.1.1.81 n-octanoyl-dl-homoserine lactone bacillus thuringiensis 0.0446 0.0446 1 PMID:24233057 -3.1.1.81 n-octanoyl-dl-homoserine lactone vulcanisaeta moutnovskia 0.59 0.59 1 PMID:25670483 -3.1.1.81 n-octanoyl-l-homoserine lactone bacillus sp. (in: firmicutes) 27.5 27.5 1 PMID:14734559 -3.1.1.81 n-octanoyl-l-homoserine lactone bacillus thuringiensis 57.0 45.5 2 PMID:23387521 -3.1.1.81 n-octanoyl-l-homoserine lactone chryseobacterium sp. strb126 45.0 45.0 1 PMID:26115006 -3.1.1.81 n-octanoyl-l-homoserine lactone enterobacter sp. cs66 80.07 80.07 1 PMID:29518220 -3.1.1.81 n-octanoyl-l-homoserine lactone flagellimonas olearia 158.0 158.0 1 PMID:25398866 -3.1.1.81 n-octanoyl-l-homoserine lactone geobacillus kaustophilus 0.52 0.52 2 PMID:20980257 -3.1.1.81 n-octanoyl-l-homoserine lactone saccharococcus caldoxylosilyticus 1.29 1.29 1 PMID:30864300 -3.1.1.81 n-pentanoyl-l-homoserine lactone bacillus thuringiensis 45.0 44.0 2 PMID:23387521 -3.1.1.81 n-pentanoyl-l-homoserine lactone chryseobacterium sp. strb126 57.0 57.0 1 PMID:26115006 -3.1.1.81 n-tetradecanoyl-l-homoserine lactone kurthia huakuii 0.038 0.038 1 PMID:29662232 -3.1.1.81 nonanoic-delta-lactone vulcanisaeta moutnovskia 88.91 88.91 1 PMID:25670483 -3.1.1.81 nonanoic-gamma-lactone vulcanisaeta moutnovskia 44.49 44.49 1 PMID:25670483 -3.1.1.81 paraoxon geobacillus kaustophilus 0.0031 0.0031 1 PMID:20980257 -3.1.1.81 rac-gamma-caprolactone vulcanisaeta moutnovskia 112.3 112.3 1 PMID:25670483 -3.1.1.81 undecanoic-delta-lactone vulcanisaeta moutnovskia 60.78 60.78 1 PMID:25670483 -3.1.1.81 undecanoic-gamma-lactone vulcanisaeta moutnovskia 8.86 8.86 1 PMID:25670483 -3.1.1.81 whiskey lactone saccharococcus caldoxylosilyticus 1.0 1.0 1 PMID:30864300 -3.1.1.84 (-)-cocaine homo sapiens 51.0 0.06815 4 PMID:20060817;PMID:20971807;PMID:30080993;PMID:32101217 -3.1.1.84 6-monoacetylmorphine homo sapiens 0.0037 0.0037 1 PMID:30080993 -3.1.1.84 cocaethylene homo sapiens 0.055 0.055 1 PMID:32101217 -3.1.1.84 cocaethylene rhodococcus sp. (in: high g+c gram-positive bacteria) 9.4 9.4 1 PMID:12369817 -3.1.1.84 cocaine rhodococcus sp. (in: high g+c gram-positive bacteria) 2323.0 51.4 5 PMID:12369817;PMID:18987161;PMID:20436035;PMID:21890748;PMID:22404344 -3.1.1.84 heroin homo sapiens 35.8 35.8 1 PMID:30080993 -3.1.1.84 norcocaethylene homo sapiens 0.1583 0.1583 1 PMID:32101217 -3.1.1.84 norcocaine homo sapiens 0.047 0.047 1 PMID:32101217 -3.1.1.85 4-nitrophenyl acetate escherichia coli 18.5 18.5 1 PMID:12732651 -3.1.1.85 4-nitrophenyl butyrate escherichia coli 6.1 6.1 1 PMID:12732651 -3.1.1.85 4-nitrophenyl caproate escherichia coli 4.0 4.0 1 PMID:12732651 -3.1.1.85 4-nitrophenyl laurate escherichia coli 1.5 1.5 1 PMID:12732651 -3.1.1.85 4-nitrophenyl propionate escherichia coli 13.1 13.1 1 PMID:12732651 -3.1.1.88 (alphar)-fenpropathrin sphingobium sp. 2.61 2.61 1 PMID:19581484 -3.1.1.88 (alphar,2r)-fenvalerate sphingobium sp. 0.91 0.91 1 PMID:19581484 -3.1.1.88 (alphar,2s)-fenvalerate sphingobium sp. 0.91 0.91 1 PMID:19581484 -3.1.1.88 (alphas)-fenpropathrin sphingobium sp. 2.61 2.61 1 PMID:19581484 -3.1.1.88 (alphas,2r)-fenvalerate sphingobium sp. 0.91 0.91 1 PMID:19581484 -3.1.1.88 (alphas,2s)-fenvalerate sphingobium sp. 0.91 0.91 1 PMID:19581484 -3.1.1.88 4-nitrophenyl acetate escherichia coli 289.1 289.1 1 PMID:22409882 -3.1.1.88 4-nitrophenyl acetate uncultured bacterium 289.12 289.12 1 PMID:28490329 -3.1.1.88 4-nitrophenyl butyrate escherichia coli 163.3 163.3 1 PMID:22409882 -3.1.1.88 4-nitrophenyl butyrate uncultured microorganism 417.15 410.31 2 PMID:28893251 -3.1.1.88 4-nitrophenyl caproate escherichia coli 88.9 88.9 1 PMID:22409882 -3.1.1.88 4-nitrophenyl caprylate escherichia coli 149.7 149.7 1 PMID:22409882 -3.1.1.88 4-nitrophenyl decanoate escherichia coli 69.1 69.1 1 PMID:22409882 -3.1.1.88 4-nitrophenyl laurate escherichia coli 49.1 49.1 1 PMID:22409882 -3.1.1.88 alpha-naphthyl acetate plutella xylostella 9.85 9.85 1 PMID:33338816 -3.1.1.88 bifenthrin sphingobium sp. 0.44 0.44 1 PMID:19581484 -3.1.1.88 cis-cypermethrin sphingobium sp. 2.57 2.57 1 PMID:19581484 -3.1.1.88 cis-permethrin sphingobium sp. 3.0 3.0 1 PMID:19581484 -3.1.1.88 cyhalothrin sphingobium sp. 1.28 1.28 1 PMID:19581484 -3.1.1.88 deltamethrin sphingobium sp. 0.79 0.79 1 PMID:19581484 -3.1.1.88 trans-cypermethrin sphingobium sp. 2.53 2.53 1 PMID:19581484 -3.1.1.88 trans-permethrin sphingobium sp. 3.03 3.03 1 PMID:19581484 -3.1.1.90 all-trans retinyl ester danio rerio 0.00044 0.00044 1 PMID:21235714 -3.1.1.92 4-sulfomuconolactone agrobacterium tumefaciens 6.7 6.7 1 PMID:17660282 -3.1.1.92 4-sulfomuconolactone hydrogenophaga intermedia 45.0 45.0 1 PMID:17660282 -3.1.1.96 d-tyr-trnatyr thermus thermophilus 0.37 0.37 1 PMID:30718305 -3.1.1.96 d-tyrosyl-trnatyr arabidopsis thaliana 300.0 300.0 1 PMID:17251192 -3.1.1.96 d-tyrosyl-trnatyr escherichia coli 6.0 6.0 1 PMID:10383414 -3.1.1.96 d-tyrosyl-trnatyr synechocystis sp. 7.5 7.5 1 PMID:19332551 -3.1.11.1 3'-end 6-fluorescein-labeled poly(dt)10 homo sapiens 0.045 0.045 1 PMID:35934053 -3.1.11.1 3'-end 6-fluorescein-labeled poly(dt)10-5'-phosphate homo sapiens 0.083 0.083 1 PMID:35934053 -3.1.11.1 3'-end 6-fluorescein-labeled poly(dt)20 homo sapiens 0.085 0.085 1 PMID:35934053 -3.1.11.1 5'-end 6-fluorescein-labeled poly(dt)10 homo sapiens 0.047 0.047 1 PMID:35934053 -3.1.11.1 5'-end 6-fluorescein-labeled poly(dt)20 homo sapiens 0.08 0.08 1 PMID:35934053 -3.1.11.1 single-stranded dna escherichia coli 115.5 115.5 1 PMID:19527069 -3.1.11.1 ssdna 10 mer thermus thermophilus 7.5 4.105 2 PMID:20457749 -3.1.11.1 ssdna 21 mer thermus thermophilus 5.3 2.85 2 PMID:20457749 -3.1.11.1 ssdna 28 mer thermus thermophilus 1.9 1.065 2 PMID:20457749 -3.1.11.1 ssdna 40 mer thermus thermophilus 2.3 1.2349999999999999 2 PMID:20457749 -3.1.11.1 ssdna 50 mer thermus thermophilus 1.0 0.595 2 PMID:20457749 -3.1.11.2 n1 duplex dna mycobacterium tuberculosis 0.012 0.012 1 PMID:25748880 -3.1.11.3 double-stranded dna escherichia coli 11.7 8.85 2 PMID:5276049 -3.1.11.3 double-stranded dna lambdavirus lambda 11.7 8.85 2 PMID:5276049 -3.1.11.5 34-mer ssdna escherichia coli 1.4 1.4 1 PMID:16388588 -3.1.11.5 atp escherichia coli 740.0 495.0 2 PMID:2545238;PMID:2545239 -3.1.11.5 double-stranded dna escherichia coli 3.7 3.7 1 PMID:16388588 -3.1.11.7 adenosine-5'-diphospho-5'-[dna] homo sapiens 0.51 0.445 2 PMID:29934293 -3.1.13.1 poly(a) escherichia coli 0.41 0.41 1 PMID:19458082 -3.1.13.2 dna-15-nucleotide-rna hybrid human immunodeficiency virus 1 0.0135 0.0135 1 PMID:15683243 -3.1.13.2 dna-16-nucleotide-rna hybrid human immunodeficiency virus 1 0.017 0.017 1 PMID:15683243 -3.1.13.2 dna-17-nucleotide-rna hybrid human immunodeficiency virus 1 0.0018 0.0018 1 PMID:15683243 -3.1.13.2 dna-18-nucleotide-rna hybrid human immunodeficiency virus 1 0.0032 0.0032 1 PMID:15683243 -3.1.13.2 dna-rna hybrid homo sapiens 3.5 3.5 1 PMID:23078533 -3.1.13.2 poly(ra)n-poly(dt)n human immunodeficiency virus 1 0.0031 0.0031 1 PMID:12614605 -3.1.13.3 5'-p-nitrophenyl-tmp escherichia coli 2.3 2.2249999999999996 2 PMID:18023590 -3.1.13.3 5'-p-nitrophenyl-tmp homo sapiens 8.767 4.6935 4 PMID:18023590 -3.1.13.3 5'-p-nitrophenyl-tmp mycolicibacterium smegmatis 10.88 5.6435 4 PMID:18023590 -3.1.13.3 5'-phosphoguanylyl-(3',5')-guanosine vibrio cholerae 0.14 0.14 1 PMID:35074425 -3.1.13.4 poly(a) bos taurus 0.02 0.02 1 * -3.1.13.4 poly(a) homo sapiens 7.6 3.3499999999999996 4 PMID:23388391 -3.1.15.1 adp trimeresurus stejnegeri 0.23 0.23 1 PMID:20331418 -3.1.15.1 atp trimeresurus stejnegeri 2.68 2.68 1 PMID:20331418 -3.1.15.1 bis(4-nitrophenyl) phosphate crotalus durissus terrificus 0.14 0.14 1 PMID:33636276 -3.1.15.1 nicotinamide adenine dinucleotide trimeresurus stejnegeri 0.82 0.82 1 PMID:20331418 -3.1.15.1 nicotinamide guanine dinucleotide trimeresurus stejnegeri 3.65 3.65 1 PMID:20331418 -3.1.16.1 flap34endo plasmodium falciparum 9.1 9.1 1 PMID:17928073 -3.1.16.1 flap34endo plasmodium yoelii 4.9 4.9 1 PMID:17928073 -3.1.2.1 acetyl-coa mus musculus 7.26 7.26 1 PMID:23709691 -3.1.2.12 4-nitrophenyl acetate agrobacterium tumefaciens 1.95 1.95 1 PMID:19653299 -3.1.2.12 4-nitrophenyl acetate escherichia coli 0.3 0.28 2 PMID:16567800 -3.1.2.12 4-nitrophenyl acetate saccharomyces cerevisiae 1.8 1.8 2 PMID:18707125;PMID:22906720 -3.1.2.12 4-nitrophenyl acetate shewanella frigidimarina 0.31 0.31 1 PMID:31426813 -3.1.2.12 4-nitrophenyl butyrate agrobacterium tumefaciens 4.48 4.48 1 PMID:19653299 -3.1.2.12 4-nitrophenyl butyrate escherichia coli 0.36 0.36 1 PMID:16567800 -3.1.2.12 4-nitrophenyl butyrate saccharomyces cerevisiae 0.2 0.2 1 PMID:18707125 -3.1.2.12 4-nitrophenyl caproate agrobacterium tumefaciens 0.67 0.67 1 PMID:19653299 -3.1.2.12 4-nitrophenyl caproate escherichia coli 0.49 0.49 1 PMID:16567800 -3.1.2.12 4-nitrophenyl propionate agrobacterium tumefaciens 1.84 1.84 1 PMID:19653299 -3.1.2.12 4-nitrophenyl propionate escherichia coli 0.37 0.255 2 PMID:16567800 -3.1.2.12 alpha-naphthyl acetate escherichia coli 5.09 4.195 2 PMID:16567800 -3.1.2.12 alpha-naphthyl propionate agrobacterium tumefaciens 1.9 1.9 1 PMID:19653299 -3.1.2.12 naphthalen-1-yl n-butanoate agrobacterium tumefaciens 1.73 1.73 1 PMID:19653299 -3.1.2.12 s-formylglutathione escherichia coli 28.5 17.505 2 PMID:16567800 -3.1.2.12 s-lactoylglutathione escherichia coli 1.02 0.535 2 PMID:16567800 -3.1.2.12 s-lactoylglutathione saccharomyces cerevisiae 116.0 116.0 1 PMID:22906720 -3.1.2.14 (9z)-hexadec-9-enoyl-[acyl-carrier protein] helianthus annuus 0.9 0.9 1 PMID:15841386 -3.1.2.14 decanoyl-[acyl-carrier protein] cuphea hookeriana 0.33 0.33 1 PMID:29470618 -3.1.2.14 dodecanoyl-[acyl-carrier protein] cuphea hookeriana 0.094 0.065 2 PMID:37047837 -3.1.2.14 myristoleoyl-[acyl-carrier protein] arabidopsis thaliana 0.22 0.112 2 PMID:12061798 -3.1.2.14 myristoyl-[acyl-carrier protein] arabidopsis thaliana 0.02 0.014 2 PMID:12061798 -3.1.2.14 octanoyl-[acyl-carrier protein] cuphea hookeriana 0.106 0.0645 2 PMID:37047837 -3.1.2.14 octanoyl-[acyl-carrier protein] cuphea palustris 1.14 1.14 1 PMID:30064208 -3.1.2.14 oleoyl-[acyl-carrier protein] arabidopsis thaliana 6.08 2.44 4 PMID:12061798 -3.1.2.14 oleoyl-[acyl-carrier protein] helianthus annuus 25.5 11.4 5 PMID:15841386;PMID:27095109 -3.1.2.14 oleoyl-[acyl-carrier protein] koelreuteria paniculata 15.81 13.4 2 PMID:33102858 -3.1.2.14 oleoyl-[acyl-carrier protein] macadamia tetraphylla 0.98 0.615 2 PMID:21071236 -3.1.2.14 oleoyl-[acyl-carrier protein] ricinus communis 7.99 4.33 2 PMID:20382402 -3.1.2.14 oleoyl-[acyl-carrier-protein] camelina sativa 7.0 4.0 2 PMID:25212866 -3.1.2.14 oleoyl-[acyl-carrier-protein] helianthus annuus 35.6 35.6 1 PMID:24327259 -3.1.2.14 palmitoleoyl-[acyl-carrier protein] arabidopsis thaliana 6.08 0.74 3 PMID:12061798 -3.1.2.14 palmitoleoyl-[acyl-carrier protein] camelina sativa 0.1 0.08 2 PMID:25212866 -3.1.2.14 palmitoleoyl-[acyl-carrier protein] helianthus annuus 8.0 8.0 1 PMID:24327259 -3.1.2.14 palmitoleoyl-[acyl-carrier protein] macadamia tetraphylla 0.45 0.3 2 PMID:21071236 -3.1.2.14 palmitoleoyl-[acyl-carrier protein] ricinus communis 1.62 0.92 2 PMID:20382402 -3.1.2.14 palmitoyl-[acyl-carrier protein] arabidopsis thaliana 2.4 1.22 2 PMID:12061798 -3.1.2.14 palmitoyl-[acyl-carrier protein] camelina sativa 4.4 2.35 2 PMID:25212866 -3.1.2.14 palmitoyl-[acyl-carrier protein] helianthus annuus 9.6 0.81 6 PMID:15841386;PMID:24327259;PMID:27095109 -3.1.2.14 palmitoyl-[acyl-carrier protein] koelreuteria paniculata 0.56 0.48000000000000004 2 PMID:33102858 -3.1.2.14 palmitoyl-[acyl-carrier protein] macadamia tetraphylla 0.44 0.235 2 PMID:21071236 -3.1.2.14 palmitoyl-[acyl-carrier protein] ricinus communis 0.46 0.435 2 PMID:20382402 -3.1.2.14 stearoyl-[acyl-carrier protein] arabidopsis thaliana 6.08 0.91 3 PMID:12061798 -3.1.2.14 stearoyl-[acyl-carrier protein] camelina sativa 0.6 0.5 2 PMID:25212866 -3.1.2.14 stearoyl-[acyl-carrier protein] helianthus annuus 26.5 0.6000000000000001 6 PMID:15841386;PMID:24327259;PMID:27095109 -3.1.2.14 stearoyl-[acyl-carrier protein] koelreuteria paniculata 9.85 8.96 2 PMID:33102858 -3.1.2.14 stearoyl-[acyl-carrier protein] macadamia tetraphylla 0.88 0.53 2 PMID:21071236 -3.1.2.14 stearoyl-[acyl-carrier protein] ricinus communis 0.56 0.47000000000000003 2 PMID:20382402 -3.1.2.17 (s)-methylmalonyl-coa rattus norvegicus 23.3 23.3 1 PMID:3071714;PMID:6885824 -3.1.2.2 benzoyl-coa mycobacterium tuberculosis 0.004 0.004 1 PMID:17524985 -3.1.2.2 crotonyl-coa mycobacterium tuberculosis 0.0078 0.0078 1 PMID:17524985 -3.1.2.2 decanoyl-coa buckleyzyma aurantiaca 136.0 136.0 2 PMID:11279019 -3.1.2.2 dodecanoyl-coa mycobacterium tuberculosis 0.01 0.01 1 PMID:17524985 -3.1.2.2 hexanoyl-coa mycobacterium tuberculosis 0.012 0.012 1 PMID:17524985 -3.1.2.2 lauroyl-coa escherichia coli 10.13 6.115 4 PMID:16515533;PMID:17604237 -3.1.2.2 lauroyl-coa mycobacterium tuberculosis 0.015 0.015 1 PMID:17524985 -3.1.2.2 myristoyl-coa buckleyzyma aurantiaca 183.0 183.0 2 PMID:11279019 -3.1.2.2 n-carbobenzoxy-l-tyrosine p-nitrophenyl ester escherichia coli 88.99 56.394999999999996 2 PMID:16515533 -3.1.2.2 octanoyl-coa buckleyzyma aurantiaca 159.0 159.0 2 PMID:11279019 -3.1.2.2 p-nitrophenyl butyrate escherichia coli 15.29 7.92 2 PMID:16515533 -3.1.2.2 palmitoleoyl-coa buckleyzyma aurantiaca 106.0 106.0 2 PMID:11279019 -3.1.2.2 palmitoyl-coa buckleyzyma aurantiaca 153.0 153.0 2 PMID:11279019 -3.1.2.2 palmitoyl-coa mycobacterium tuberculosis 0.037 0.037 1 PMID:17524985 -3.1.2.2 stearoyl-coa buckleyzyma aurantiaca 121.0 121.0 2 PMID:11279019 -3.1.2.2 stearoyl-coa mycobacterium tuberculosis 0.019 0.019 1 PMID:17524985 -3.1.2.20 2,3-dihydroxybenzoyl-coa escherichia coli k-12 0.372 0.372 1 PMID:19193103 -3.1.2.20 2,3-dihydroxybenzoyl-entb escherichia coli k-12 0.14 0.14 1 PMID:19193103 -3.1.2.20 2,4-dihydroxybenzoyl-coa escherichia coli k-12 0.0342 0.0342 1 PMID:19193103 -3.1.2.20 2-butenoyl-coa homo sapiens 0.014 0.014 1 PMID:19170545 -3.1.2.20 2-butenoyl-coa mus musculus 11.0 11.0 1 PMID:22993230 -3.1.2.20 3,4-dihydroxybenzoyl-coa escherichia coli k-12 0.23 0.23 1 PMID:19193103 -3.1.2.20 3,4-dihydroxyphenylacetyl-coa homo sapiens 0.19 0.19 1 PMID:19170545 -3.1.2.20 3,5-cis-dodecadienoyl-coa escherichia coli 21.6 21.6 1 PMID:18576672 -3.1.2.20 3,5-cis-tetradecadienoyl-coa escherichia coli 3.7 3.7 1 PMID:18576672 -3.1.2.20 3,5-dihydroxybenzoyl-coa escherichia coli k-12 7.45 7.45 1 PMID:19193103 -3.1.2.20 3,5-dihydroxyphenylacetyl-coa homo sapiens 0.19 0.19 1 PMID:19170545 -3.1.2.20 3-hydroxy-3-methylglutaryl-coa homo sapiens 0.079 0.079 1 PMID:19170545 -3.1.2.20 3-hydroxy-3-methylglutaryl-coa mus musculus 0.007 0.007 1 PMID:19405909 -3.1.2.20 3-hydroxybenzoyl-coa escherichia coli k-12 10.3 10.3 1 PMID:19193103 -3.1.2.20 3-hydroxybenzoyl-coa homo sapiens 0.011 0.011 1 PMID:19170545 -3.1.2.20 3-hydroxybutyryl-coa mus musculus 0.046 0.046 1 PMID:19405909 -3.1.2.20 3-hydroxyphenylacetyl-coa haemophilus influenzae 140.0 140.0 1 PMID:18247525 -3.1.2.20 3-hydroxyphenylacetyl-coa homo sapiens 1.4 1.4 1 PMID:19170545 -3.1.2.20 3-hydroxytetradecanoyl-coa escherichia coli 10.7 10.7 1 PMID:18576672 -3.1.2.20 4-chlorobenzoyl-coa homo sapiens 0.0032 0.0032 1 PMID:19170545 -3.1.2.20 4-hydroxybenzoyl-coa escherichia coli 0.0062 0.0062 1 PMID:18247525 -3.1.2.20 4-hydroxybenzoyl-coa escherichia coli k-12 0.207 0.207 1 PMID:19193103 -3.1.2.20 4-hydroxybenzoyl-coa haemophilus influenzae 0.078 0.078 1 PMID:18247525 -3.1.2.20 4-hydroxyphenylacetyl-coa haemophilus influenzae 75.0 75.0 1 PMID:18247525 -3.1.2.20 4-hydroxyphenylacetyl-coa homo sapiens 0.14 0.14 1 PMID:19170545 -3.1.2.20 acetoacetyl-coa haemophilus influenzae 35.0 35.0 1 PMID:18247525 -3.1.2.20 acetyl-coa escherichia coli 0.55 0.55 1 PMID:18247525 -3.1.2.20 acetyl-coa haemophilus influenzae 1.3 1.3 1 PMID:18247525 -3.1.2.20 acetyl-coa homo sapiens 0.054 0.054 1 PMID:19170545 -3.1.2.20 acetyl-coa mus musculus 24.0 24.0 1 PMID:22993230 -3.1.2.20 acetyl-coa streptomyces chartreusis 0.021 0.021 1 PMID:29654175 -3.1.2.20 acetyl-s-n-acetylcysteamine streptomyces sp. 1.193 1.193 1 PMID:18836004 -3.1.2.20 arachidonoyl-coa homo sapiens 1.4 0.711 2 PMID:19170545;PMID:22586271 -3.1.2.20 arachidonoyl-coa mus musculus 1.2 1.2 1 PMID:22993230 -3.1.2.20 arachidoyl-coa haemophilus influenzae 0.27 0.27 1 PMID:18247525 -3.1.2.20 benzoyl-coa escherichia coli k-12 13.9 13.9 1 PMID:19193103 -3.1.2.20 benzoyl-coa streptomyces chartreusis 0.015 0.015 1 PMID:29654175 -3.1.2.20 beta-hydroxybutyryl-coa homo sapiens 0.18 0.18 1 PMID:19170545 -3.1.2.20 beta-methylcrotonyl-coa escherichia coli 0.1 0.1 1 PMID:18247525 -3.1.2.20 beta-methylcrotonyl-coa haemophilus influenzae 0.54 0.54 1 PMID:18247525 -3.1.2.20 beta-methylcrotonyl-coa homo sapiens 0.023 0.023 1 PMID:19170545 -3.1.2.20 butyryl-coa haemophilus influenzae 6.7 6.7 1 PMID:18260643 -3.1.2.20 butyryl-coa streptomyces chartreusis 0.021 0.021 1 PMID:29654175 -3.1.2.20 butyrylpantetheine phosphate haemophilus influenzae 0.08 0.08 1 PMID:18260643 -3.1.2.20 cezomycin-coa streptomyces chartreusis 0.3 0.3 1 PMID:29654175 -3.1.2.20 crotonyl-coa haemophilus influenzae 0.92 0.92 1 PMID:18247525 -3.1.2.20 crotonyl-coa homo sapiens 0.0076 0.0076 1 PMID:19170545 -3.1.2.20 decanoyl-coa buckleyzyma aurantiaca 136.0 136.0 1 PMID:11279019 -3.1.2.20 decanoyl-coa escherichia coli 1.46 1.46 1 PMID:35876515 -3.1.2.20 decanoyl-coa mus musculus 0.055 0.055 1 PMID:19405909 -3.1.2.20 dl-3-hydroxy-3-methylglutaryl-coa haemophilus influenzae 8.9 8.9 1 PMID:18247525 -3.1.2.20 dl-3-hydroxy-3-methylglutaryl-coa mus musculus 12.0 12.0 1 PMID:22993230 -3.1.2.20 dl-3-hydroxybutyryl-coa haemophilus influenzae 8.3 8.3 1 PMID:18247525 -3.1.2.20 dl-3-hydroxybutyryl-coa mus musculus 13.0 13.0 1 PMID:22993230 -3.1.2.20 glutaryl-coa haemophilus influenzae 100.0 100.0 1 PMID:18247525 -3.1.2.20 glutaryl-coa homo sapiens 0.05 0.05 1 PMID:19170545 -3.1.2.20 hexanoyl-coa haemophilus influenzae 15.0 15.0 1 PMID:18247525 -3.1.2.20 hexanoyl-coa mus musculus 0.03 0.03 1 PMID:19405909 -3.1.2.20 isobutyryl-coa escherichia coli 9.5 9.5 1 PMID:18247525 -3.1.2.20 isobutyryl-coa haemophilus influenzae 140.0 139.0 2 PMID:18247525;PMID:18260643 -3.1.2.20 isovaleryl-coa haemophilus influenzae 30.0 30.0 1 PMID:18247525 -3.1.2.20 lauroyl-coa escherichia coli 9.6 5.6 2 PMID:18247525;PMID:18576672 -3.1.2.20 lauroyl-coa haemophilus influenzae 9.2 9.2 2 PMID:18247525;PMID:18260643 -3.1.2.20 lauroyl-coa homo sapiens 0.019 0.019 1 PMID:19170545 -3.1.2.20 lauroyl-coa mus musculus 5.3 2.669 2 PMID:19405909;PMID:22993230 -3.1.2.20 linolenoyl-coa homo sapiens 13.3 13.3 1 PMID:22586271 -3.1.2.20 linoleoyl-coa haemophilus influenzae 2.0 2.0 1 PMID:18247525 -3.1.2.20 linoleoyl-coa homo sapiens 12.2 6.108499999999999 2 PMID:19170545;PMID:22586271 -3.1.2.20 linoleoyl-coa mus musculus 2.7 2.7 1 PMID:22993230 -3.1.2.20 malonyl-coa haemophilus influenzae 3.3 3.3 1 PMID:18247525 -3.1.2.20 malonyl-coa homo sapiens 0.066 0.066 1 PMID:19170545 -3.1.2.20 malonyl-coa mus musculus 9.6 4.8069999999999995 2 PMID:19405909;PMID:22993230 -3.1.2.20 malonyl-coa streptomyces chartreusis 0.017 0.017 1 PMID:29654175 -3.1.2.20 methylmalonyl-coa haemophilus influenzae 1.1 1.1 1 PMID:18247525 -3.1.2.20 methylmalonyl-coa homo sapiens 0.083 0.083 1 PMID:19170545 -3.1.2.20 myristoyl-coa buckleyzyma aurantiaca 183.0 183.0 1 PMID:11279019 -3.1.2.20 myristoyl-coa escherichia coli 6.2 6.2 1 PMID:18576672 -3.1.2.20 myristoyl-coa haemophilus influenzae 6.9 6.9 1 PMID:18247525 -3.1.2.20 myristoyl-coa homo sapiens 19.7 0.07 3 PMID:19170545;PMID:22586271 -3.1.2.20 myristoyl-coa mus musculus 4.7 0.062 7 PMID:19405909;PMID:22993230 -3.1.2.20 n-acetylcysteamine acetate streptomyces coelicolor 7.5 7.5 1 PMID:19074611 -3.1.2.20 n-acetylcysteamine butyrate streptomyces coelicolor 1.817 1.817 1 PMID:19074611 -3.1.2.20 n-acetylcysteamine propionate streptomyces coelicolor 0.9 0.9 1 PMID:19074611 -3.1.2.20 n-butyryl-coa escherichia coli 6.7 6.7 1 PMID:18247525 -3.1.2.20 n-butyryl-coa haemophilus influenzae 22.0 22.0 1 PMID:18247525 -3.1.2.20 n-butyryl-coa homo sapiens 0.047 0.047 1 PMID:19170545 -3.1.2.20 n-butyryl-pantetheine phosphate escherichia coli 0.082 0.082 1 PMID:18247525 -3.1.2.20 n-butyrylpantethiene phosphate haemophilus influenzae 0.8 0.8 1 PMID:18247525 -3.1.2.20 n-decanoyl-coa escherichia coli 17.0 17.0 1 PMID:18247525 -3.1.2.20 n-decanoyl-coa haemophilus influenzae 13.0 13.0 1 PMID:18247525 -3.1.2.20 n-decanoyl-coa homo sapiens 0.016 0.016 1 PMID:19170545 -3.1.2.20 n-hexanoyl-coa homo sapiens 0.022 0.022 1 PMID:19170545 -3.1.2.20 n-octanoyl-coa haemophilus influenzae 4.6 4.6 1 PMID:18247525 -3.1.2.20 n-octanoyl-coa homo sapiens 0.0047 0.0047 1 PMID:19170545 -3.1.2.20 n-propionyl-coa homo sapiens 0.036 0.036 1 PMID:19170545 -3.1.2.20 octanoyl-coa buckleyzyma aurantiaca 159.0 159.0 1 PMID:11279019 -3.1.2.20 oleoyl-coa escherichia coli 13.0 13.0 1 PMID:18247525 -3.1.2.20 oleoyl-coa haemophilus influenzae 1.7 1.7 1 PMID:18247525 -3.1.2.20 oleoyl-coa homo sapiens 0.011 0.011 1 PMID:19170545 -3.1.2.20 oleoyl-coa mus musculus 3.2 1.6305 2 PMID:19405909;PMID:22993230 -3.1.2.20 palmitoleoyl-coa buckleyzyma aurantiaca 106.0 106.0 1 PMID:11279019 -3.1.2.20 palmitoleoyl-coa haemophilus influenzae 5.7 5.7 1 PMID:18247525 -3.1.2.20 palmitoleoyl-coa homo sapiens 11.5 5.7585 2 PMID:19170545;PMID:22586271 -3.1.2.20 palmitoleoyl-coa mus musculus 4.7 4.7 1 PMID:22993230 -3.1.2.20 palmitoyl-coa buckleyzyma aurantiaca 153.0 153.0 1 PMID:11279019 -3.1.2.20 palmitoyl-coa escherichia coli 10.2 3.7 3 PMID:18247525;PMID:18576672;PMID:35876515 -3.1.2.20 palmitoyl-coa escherichia coli k-12 0.154 0.154 1 PMID:19193103 -3.1.2.20 palmitoyl-coa haemophilus influenzae 2.7 2.7 1 PMID:18247525 -3.1.2.20 palmitoyl-coa homo sapiens 16.6 8.302200000000001 2 PMID:19170545;PMID:22586271 -3.1.2.20 palmitoyl-coa mus musculus 8.5 0.0475 4 PMID:19405909;PMID:22993230 -3.1.2.20 palmitoyl-coa streptomyces chartreusis 0.0009 0.0009 1 PMID:29654175 -3.1.2.20 phenylacetyl-coa escherichia coli 9.4 9.4 1 PMID:18247525 -3.1.2.20 phenylacetyl-coa haemophilus influenzae 130.0 130.0 1 PMID:18247525 -3.1.2.20 phenylacetyl-coa homo sapiens 0.084 0.084 1 PMID:19170545 -3.1.2.20 phenylacetyl-coa mus musculus 3.2 1.6600000000000001 2 PMID:19405909;PMID:22993230 -3.1.2.20 propionyl-coa haemophilus influenzae 25.0 25.0 1 PMID:18247525 -3.1.2.20 propionyl-s-n-acetylcysteamine streptomyces sp. 1.82 1.82 1 PMID:18836004 -3.1.2.20 salicylyl-coa escherichia coli k-12 4.63 4.63 1 PMID:19193103 -3.1.2.20 salicylyl-entb escherichia coli k-12 4.83 4.83 1 PMID:19193103 -3.1.2.20 stearoyl-coa arabidopsis thaliana 5.7 5.7 1 PMID:23288899 -3.1.2.20 stearoyl-coa buckleyzyma aurantiaca 121.0 121.0 1 PMID:11279019 -3.1.2.20 stearoyl-coa haemophilus influenzae 0.77 0.77 1 PMID:18247525 -3.1.2.20 stearoyl-coa homo sapiens 1.2 0.6054999999999999 2 PMID:19170545;PMID:22586271 -3.1.2.20 stearoyl-coa mus musculus 2.3 2.3 1 PMID:22993230 -3.1.2.20 succinyl-coa haemophilus influenzae 190.0 190.0 1 PMID:18247525 -3.1.2.20 tiglyl-coa haemophilus influenzae 2.6 2.6 1 PMID:18247525 -3.1.2.20 tiglyl-coa homo sapiens 0.02 0.02 1 PMID:19170545 -3.1.2.20 vaccenoyl-coa homo sapiens 1.8 1.8 1 PMID:22586271 -3.1.2.23 4-chlorobenzoate pseudomonas sp. 0.123 0.123 1 PMID:1610806 -3.1.2.23 4-chlorobenzoyl-coa pseudomonas sp. 1.1 1.1 1 PMID:16962159 -3.1.2.23 4-fluorobenzoyl-coa pseudomonas sp. 9.7 9.7 1 PMID:16962159 -3.1.2.23 4-hydroxybenzoyl-coa aromatoleum evansii 10.0 10.0 1 PMID:18542924 -3.1.2.23 4-hydroxybenzoyl-coa arthrobacter sp. 6.7 4.55 2 PMID:22873756 -3.1.2.23 4-hydroxybenzoyl-coa pseudomonas sp. 18.3 12.55 2 PMID:1610806;PMID:16962159 -3.1.2.23 4-methoxybenzoyl-coa pseudomonas sp. 0.27 0.27 1 PMID:16962159 -3.1.2.23 4-methylbenzoyl-coa pseudomonas sp. 0.047 0.047 1 PMID:16962159 -3.1.2.23 4-trifluoromethylbenzoyl-coa pseudomonas sp. 0.038 0.038 1 PMID:16962159 -3.1.2.23 benzoyl-coa aromatoleum evansii 3.0 3.0 1 PMID:18542924 -3.1.2.23 benzoyl-coa pseudomonas sp. 1.0 0.63 2 PMID:1610806;PMID:16962159 -3.1.2.25 decanoyl-coa streptococcus pneumoniae 32.8 32.8 1 PMID:26538563 -3.1.2.25 phenylacetyl-coa streptococcus pneumoniae 6.5 6.5 1 PMID:26538563 -3.1.2.28 1,4-dihydroxy-2-naphthoyl-coa escherichia coli 6.2 3.165 2 PMID:23564174 -3.1.2.28 1,4-dihydroxy-2-naphthoyl-coa listeria monocytogenes serotype 1/2a 14.9 14.9 1 PMID:33619030 -3.1.2.28 1-hydroxy-2-naphthoyl-coa escherichia coli 14.8 14.8 1 PMID:23564174 -3.1.2.28 3,4-dihydroxybenzoyl-coa escherichia coli 23.2 23.2 1 PMID:23564174 -3.1.2.28 3,5-dihydroxybenzoyl-coa escherichia coli 12.6 12.6 1 PMID:23564174 -3.1.2.28 salicylyl-coa escherichia coli 93.0 93.0 1 PMID:23564174 -3.1.2.29 acetyl-coa streptantibioticus cattleyicolor 0.06 0.06 1 PMID:20836570 -3.1.2.29 fluoroacetyl-coa streptantibioticus cattleyicolor 390.0 0.044 3 PMID:20430898;PMID:20836570 -3.1.2.30 (s)-malyl-coa cereibacter sphaeroides 110.0 110.0 1 PMID:20047909 -3.1.2.32 acetoacetyl-coa pseudomonas aeruginosa 0.36 0.36 1 PMID:25960261 -3.1.2.32 cysteamine s-phosphate pseudomonas aeruginosa 0.022 0.022 1 PMID:25960261 -3.1.2.32 s-(4-nitrobenzoyl)mercaptoethane pseudomonas aeruginosa 0.12 0.12 1 PMID:19788310 -3.1.2.32 s-ethyl-acetothioacetate pseudomonas aeruginosa 0.85 0.85 1 PMID:25960261 -3.1.2.4 3-hydroxy-2-methylpropanoyl-coa rattus norvegicus 266.0 208.0 2 PMID:8188708 -3.1.2.4 3-hydroxyisobutyryl-coa pseudomonas aeruginosa 89.0 89.0 1 PMID:14518977 -3.1.2.6 s-acetoacetylglutathione candida albicans 82.0 82.0 1 PMID:2222487 -3.1.2.6 s-d-lactoylglutathione arabidopsis thaliana 3930.0 389.0 10 PMID:11085979;PMID:12781779;PMID:14529289;PMID:15067523;PMID:9428743 -3.1.2.6 s-d-lactoylglutathione candida albicans 142.0 142.0 1 PMID:2222487 -3.1.2.6 s-d-lactoylglutathione homo sapiens 780.0 727.0 3 PMID:11018726;PMID:19062100;PMID:8504817 -3.1.2.6 s-d-lactoylglutathione mus musculus 450.0 450.0 1 PMID:7350914 -3.1.2.6 s-d-lactoylglutathione nostoc sp. pcc 7120 = fachb-418 908.8 908.8 1 PMID:30468810 -3.1.2.6 s-d-lactoylglutathione oryza sativa 301.0 301.0 1 PMID:16931048 -3.1.2.6 s-d-lactoylglutathione plasmodium falciparum 375.0 375.0 1 PMID:19663684 -3.1.2.6 s-d-lactoylglutathione saccharomyces cerevisiae 979.0 723.0 5 PMID:10600466;PMID:21310260 -3.1.2.6 s-d-lactoylglutathione salmonella enterica 0.9 0.9 1 PMID:25673654 -3.1.2.6 s-d-lactoylglutathione salmonella enterica subsp. enterica serovar typhimurium 394.9 168.8 7 PMID:17764159;PMID:20385411 -3.1.2.6 s-d-lactoylglutathione shouchella lehensis 0.0355 0.0355 1 PMID:34502284 -3.1.2.6 s-d-lactoyltrypanothione leishmania infantum 16.0 16.0 1 PMID:21864532 -3.1.2.6 s-d-mandeloylglutathione arabidopsis thaliana 74.0 74.0 1 * -3.1.2.6 s-d-mandeloylglutathione homo sapiens 183.0 183.0 1 PMID:8504817 -3.1.2.6 s-d-mandeloylglutathione saccharomyces cerevisiae 38.1 35.1 5 PMID:10600466;PMID:21310260 -3.1.2.6 s-glycoloylglutathione homo sapiens 1740.0 1740.0 1 PMID:8504817 -3.1.2.6 s-l-glyceroylglutathione homo sapiens 1490.0 1490.0 1 PMID:8504817 -3.1.2.6 s-lactoylglutathione arabidopsis thaliana 470.0 188.0 4 PMID:15067523;PMID:16227621 -3.1.2.6 s-lactoylglutathione homo sapiens 780.0 780.0 1 PMID:8550579 -3.1.2.6 s-lactoylglutathione oryza sativa 508.0 508.0 1 PMID:25039836 -3.1.2.6 s-lactoylglutathione plasmodium falciparum 119.6 70.0 3 PMID:15843146 -3.1.2.6 s-mandeloylglutathione homo sapiens 755.0 201.0 3 PMID:8550579 -3.1.2.6 s-succinylglutathione candida albicans 68.0 68.0 1 PMID:2222487 -3.1.21.1 (25r)-3beta-hydroxycholest-5-en-27-oate potyvirus sp. 0.0214 0.0214 1 PMID:15163663 -3.1.21.1 (pc)10 homo sapiens 493.3 330.15 2 PMID:15521815 -3.1.21.1 d(pa)10 homo sapiens 106.6 106.6 1 PMID:15521815 -3.1.21.1 d(papcptpapcpapgptpcptpapcpa) homo sapiens 703.3 703.3 1 PMID:15521815 -3.1.21.1 d(pgpgpcpapcptptpapc) homo sapiens 453.3 226.6746 2 PMID:15521815 -3.1.21.1 d(pt)10 homo sapiens 713.0 713.0 1 PMID:15521815 -3.1.21.1 d(ptpapgpapapgpaptpcpapapa) homo sapiens 136.6 136.6 1 PMID:15521815 -3.1.21.1 lambda phage dna potyvirus sp. 0.0214 0.0214 1 PMID:15163663 -3.1.21.10 3'-flapped junction in dna homo sapiens 0.354 0.237 2 PMID:18310322;PMID:24692662 -3.1.21.10 3'-flapped junction in dna saccharomyces cerevisiae 0.97 0.97 1 PMID:18281703 -3.1.21.10 d-loop junction in dna saccharomyces cerevisiae 0.09 0.09 1 PMID:18281703 -3.1.21.10 dna junction 1 saccharolobus solfataricus 0.05 0.02825 2 PMID:15921693 -3.1.21.10 dna junction 1 unconstrained schizosaccharomyces pombe 0.0029 0.0014529999999999999 2 PMID:9837990 -3.1.21.10 dna junction j1t1 schizosaccharomyces pombe 0.001 0.001 1 PMID:9837990 -3.1.21.10 dna junction j1t2 schizosaccharomyces pombe 0.00034 0.00034 1 PMID:9837990 -3.1.21.10 dna junction rc1 escherichia coli 0.00416 0.00416 1 PMID:10471285 -3.1.21.10 dna junction rc1(1,3') escherichia coli 0.000566 0.000566 1 PMID:10471285 -3.1.21.10 dna junction rc1(2,3') escherichia coli 4.7e-06 4.7e-06 1 PMID:10471285 -3.1.21.10 holliday junction 3 in dna saccharolobus solfataricus 0.02 0.01007 2 PMID:10623519 -3.1.21.10 intact holliday junction homo sapiens 0.037 0.037 1 PMID:24692662 -3.1.21.10 nx12 junction in single-stranded dna homo sapiens 0.18 0.18 1 PMID:18310322 -3.1.21.10 nxo12 junction in single-stranded dna saccharomyces cerevisiae 1.2 1.2 1 PMID:18281703 -3.1.21.10 pxo12-3' junction in single-stranded dna saccharomyces cerevisiae 0.32 0.32 1 PMID:18281703 -3.1.21.10 replication fork-like junction in dna saccharomyces cerevisiae 1.35 1.35 1 PMID:18281703 -3.1.21.10 splayed y junction in dna saccharomyces cerevisiae 0.26 0.26 1 PMID:18281703 -3.1.21.10 x12 junction in single-stranded dna homo sapiens 0.0047 0.0047 1 PMID:18310322 -3.1.21.2 21-mer c grec escherichia coli 0.28 0.28 1 PMID:19751747 -3.1.21.2 5'-end-labeled 29 nucleotide double-stranded dna mycobacterium tuberculosis 0.0193 0.0193 1 PMID:23936515 -3.1.21.2 ssdna containing a (polyethylene glycol)3 spacer thermococcus eurythermalis 0.006 0.006 1 PMID:30586940 -3.1.21.2 ssdna containing a (polyethylene glycol)6 spacer thermococcus eurythermalis 0.007 0.007 1 PMID:30586940 -3.1.21.2 ssdna containing a c12 spacer thermococcus eurythermalis 0.0058 0.0058 1 PMID:30586940 -3.1.21.2 ssdna containing a c2 spacer thermococcus eurythermalis 0.0001 0.0001 1 PMID:30586940 -3.1.21.2 ssdna containing a c3 spacer thermococcus eurythermalis 0.0038 0.0038 1 PMID:30586940 -3.1.21.2 ssdna containing a c4 spacer thermococcus eurythermalis 0.0055 0.0055 1 PMID:30586940 -3.1.21.2 ssdna containing a c6 spacer thermococcus eurythermalis 0.0062 0.0062 1 PMID:30586940 -3.1.21.2 ssdna containing a cyclic deoxyribose-like structure thermococcus eurythermalis 0.0098 0.0098 1 PMID:30586940 -3.1.21.3 atp escherichia coli 167.0 167.0 1 * -3.1.21.4 cole1 dna escherichia coli 0.133 0.07485 2 * -3.1.21.4 d(g-g-t-5-bromodeoxyuridine-a-a-c-c) bacillus amyloliquefaciens 600.0 600.0 1 * -3.1.21.4 d(g-g-t-5-bromodeoxyuridine-a-a-c-c) haemophilus parainfluenzae 600.0 600.0 1 * -3.1.21.4 d(g-g-t-t-a-a-c-c) haemophilus parainfluenzae 2830.0 2830.0 1 * -3.1.21.4 d(pt-g-a-a-t-t-c-a) escherichia coli 0.0667 0.0667 1 * -3.1.21.4 dna brevibacillus brevis 0.048 0.048 1 PMID:15826661 -3.1.21.4 dna escherichia coli 0.018 0.018 1 PMID:18367450 -3.1.21.4 lambda dna escherichia coli 0.0217 0.0217 1 * -3.1.21.4 linear mneongreen dna bergeriella denitrificans 0.0037 0.0037 1 PMID:33382779 -3.1.21.4 ntp14 dna bacillus amyloliquefaciens 0.0267 0.0267 1 * -3.1.21.4 pbr322 dna escherichia coli 0.03 0.03 1 * -3.1.21.4 pjc80 dna bacillus amyloliquefaciens 0.0367 0.0367 1 * -3.1.21.4 sv40 dna escherichia coli 0.025 0.025 1 * -3.1.21.7 18-mer rna oligonucleotide containing inosine thermococcus kodakarensis 0.035 0.035 1 PMID:34928335 -3.1.21.7 30-mer dna/rna containing inosine hybrid thermococcus kodakarensis 0.0063 0.0063 1 PMID:34928335 -3.1.21.7 49-mer oligonucleotide tequatrovirus t4 0.0117 0.0117 1 PMID:9100001 -3.1.21.7 acuggaca[ri][ri]u[ri]cuccgagg mus musculus 0.0026 0.0026 1 PMID:27108838 -3.1.21.9 5'-(da)7dadadcdada(da)7-3' tequatrovirus t4 0.00576 0.00576 1 PMID:16971463 -3.1.21.9 5'-(da)7dadtdcdada(da)7-3' tequatrovirus t4 0.0167 0.0167 1 PMID:16971463 -3.1.21.9 5'-(da)8dgdtdcdadg(da)8-3' tequatrovirus t4 0.0087 0.0087 1 PMID:16971463 -3.1.22.1 supercoiled plasmid dna bos taurus 1.67e-06 7.665e-07 6 PMID:19208753 -3.1.25.1 dna 14mer containing a tt-dimer tequatrovirus t4 0.02 0.0183 3 PMID:2191719;PMID:2914925 -3.1.25.1 dna 18mer containing a tt-dimer tequatrovirus t4 0.0183 0.0183 1 PMID:2914925 -3.1.26.11 pre-trna(arg) homo sapiens 0.67 0.67 1 PMID:18421255 -3.1.26.11 pre-trna(arg1) bacillus subtilis 0.48 0.247 2 PMID:32982996 -3.1.26.11 pre-trna(arg1) methanococcus maripaludis 0.105 0.05255 2 PMID:32982996 -3.1.26.11 pre-trna(arg1) methanolobus psychrophilus 0.145 0.0726 2 PMID:32982996 -3.1.26.11 pre-trna(arg2) bacillus subtilis 0.023 0.023 1 PMID:32982996 -3.1.26.11 pre-trna(arg2) methanococcus maripaludis 0.225 0.225 1 PMID:32982996 -3.1.26.11 pre-trna(arg2) methanolobus psychrophilus 0.2 0.2 1 PMID:32982996 -3.1.26.11 pre-trna(val) homo sapiens 0.27 0.27 1 PMID:18421255 -3.1.26.11 pre-trnaarg homo sapiens 6.18 3.1005 2 PMID:16361254 -3.1.26.11 pre-trnaglu-ccun17 synechocystis sp. 0.14 0.14 1 PMID:16051605 -3.1.26.11 pre-trnaglu-cuan17 synechocystis sp. 0.28 0.28 1 PMID:16051605 -3.1.26.11 pre-trnaglu-uuan17 synechocystis sp. 2.25 2.25 1 PMID:16051605 -3.1.26.11 pre-trnagly homo sapiens 0.035 0.035 1 PMID:22336717 -3.1.26.11 pre-trnahis drosophila melanogaster 0.083 0.083 1 PMID:16618969 -3.1.26.11 pre-trnahis homo sapiens 0.237 0.237 1 PMID:22336717 -3.1.26.11 pre-trnahis-aug drosophila melanogaster 0.365 0.365 1 PMID:16618969 -3.1.26.11 pre-trnahis-cca drosophila melanogaster 0.0049 0.0049 1 PMID:16618969 -3.1.26.11 pre-trnaile homo sapiens 0.018 0.018 1 PMID:22336717 -3.1.26.11 pre-trnaleu(uur) homo sapiens 0.25 0.25 1 PMID:22336717 -3.1.26.11 pre-trnaser(ucn) homo sapiens 0.07 0.07 1 PMID:16361254 -3.1.26.11 pre-trnaser(ucn)7443c homo sapiens 0.23 0.23 1 PMID:16361254 -3.1.26.11 pre-trnaser(ucn)7444u homo sapiens 0.153 0.153 1 PMID:16361254 -3.1.26.11 pre-trnaser(ucn)7445c homo sapiens 0.012 0.012 1 PMID:16361254 -3.1.26.11 pre-trnaser(ucn)7445g homo sapiens 0.345 0.345 1 PMID:16361254 -3.1.26.11 pre-trnaser(ucn)7510g homo sapiens 0.05 0.05 1 PMID:16361254 -3.1.26.11 pre-trnaser(ucn)7511g homo sapiens 0.05 0.05 1 PMID:16361254 -3.1.26.11 pre-trnaser(ucn)7512g homo sapiens 0.05 0.05 1 PMID:16361254 -3.1.26.12 5' hydroxylated fluorogenic oligonucleotide escherichia coli 0.015 0.015 1 PMID:15197283 -3.1.26.12 5' monophosphorylated fluorogenic oligonucleotide escherichia coli 0.014 0.014 1 PMID:15197283 -3.1.26.12 5'-gggacaguauuug-3' escherichia coli 1.4 1.4 1 PMID:19161846 -3.1.26.12 5'-phosphorylated 9s rna escherichia coli 0.09316 0.034165 4 PMID:34341070 -3.1.26.12 5'-triphosphorylated 9s rna escherichia coli 0.08399 0.01607 4 PMID:34341070 -3.1.26.12 5'-triphosphorylated glmz srna escherichia coli 0.2863 0.116925 4 PMID:34341070 -3.1.26.12 aauuu-containing rna oligonucleotide escherichia coli 0.192 0.192 1 PMID:15632310 -3.1.26.12 cauuu-containing rna oligonucleotide escherichia coli 0.15 0.15 1 PMID:15632310 -3.1.26.12 gauuu-containing rna oligonucleotide escherichia coli 0.765 0.765 1 PMID:15632310 -3.1.26.12 guuuu-containing rna oligonucleotide escherichia coli 0.121 0.121 1 PMID:15632310 -3.1.26.12 uauuu-containing rna oligonucleotide escherichia coli 0.209 0.209 1 PMID:15632310 -3.1.26.12 uuuuu-containing rna oligonucleotide escherichia coli 0.015 0.015 1 PMID:15632310 -3.1.26.12 uuuuu-dn34-containing rna oligonucleotide escherichia coli 0.023 0.023 1 PMID:15632310 -3.1.26.13 poly(ra)n-poly(dt)n human immunodeficiency virus 1 0.031 0.031 1 PMID:12614605 -3.1.26.13 rna-dna hybrid human immunodeficiency virus 1 1.9 1.9 1 PMID:25092689 -3.1.26.3 515 bp dsrna drosophila melanogaster 0.0005 0.0005 3 PMID:21419681 -3.1.26.3 aa-[16s[micro-hp]rna] aquifex aeolicus 0.045 0.045 1 PMID:21138964 -3.1.26.3 r1.1 rna escherichia coli 0.14 0.029 7 PMID:11305928;PMID:11732918;PMID:15476399;PMID:27150669 -3.1.26.3 rna escherichia coli 7.7 5.75 2 PMID:11586889 -3.1.26.3 rna saccharomyces cerevisiae 1.08 1.08 1 PMID:27257067 -3.1.26.4 d14r1d3:dna18 homo sapiens 0.4 0.4 1 PMID:21177854 -3.1.26.4 dna-(1',2'-methylene-bridged azetidine-t)-antisense-rna hybrid escherichia coli 2.43 2.43 1 PMID:17411072 -3.1.26.4 dna-(2'-alkoxy-1',2'-methylene-bridged azetidine-t)-antisense-rna hybrid escherichia coli 2.5 2.5 1 PMID:17411072 -3.1.26.4 dna-(aza-ena-t)-antisense-rna hybrid escherichia coli 3.97 3.97 1 PMID:17411072 -3.1.26.4 dna-(azetidine-t)-antisense-rna hybrid escherichia coli 2.13 2.13 1 PMID:17411072 -3.1.26.4 dna-(oxetane-t)-antisense-rna hybrid escherichia coli 1.47 1.47 1 PMID:17411072 -3.1.26.4 dna-rna hybrid escherichia coli 1.54 1.54 1 PMID:17411072 -3.1.26.4 dna-rna hybrid duplex drosophila melanogaster 0.45 0.3335 2 PMID:32589740 -3.1.26.4 dna-rna hybrid duplex rd12 homo sapiens 0.16 0.16 1 PMID:35247386 -3.1.26.4 dna-rna-dna hybrid thermus thermophilus 0.082 0.082 1 PMID:11052682 -3.1.26.4 dna/rna hybrid escherichia coli 0.95 0.95 1 PMID:16223236 -3.1.26.4 polya*dt36 methanocaldococcus jannaschii 0.64 0.375 2 PMID:12534291 -3.1.26.4 rna-dna heteroduplex homo sapiens 3.5 3.5 1 PMID:23078533 -3.1.26.4 rna-dna heteroduplex pyrococcus furiosus 17.0 14.15 2 PMID:20047562 -3.1.26.4 rna-dna*dna hybrid archaeoglobus fulgidus 0.133 0.133 1 PMID:11254381 -3.1.26.4 rna-dna/dna hybrid pyrococcus abyssi 0.093 0.093 1 PMID:20472790 -3.1.26.4 rna-rna duplex pyrococcus furiosus 0.093 0.093 1 PMID:20047562 -3.1.26.4 rna18:dna18 homo sapiens 3.48 3.48 1 PMID:21177854 -3.1.26.5 human pre-trnatyr bacillus subtilis 5.6e-05 3.35e-05 2 PMID:12951523 -3.1.26.5 human pre-trnatyr escherichia coli 0.04 4e-05 3 PMID:12400701;PMID:12951523 -3.1.26.5 pmini3pbug thermotoga maritima 0.0143 0.0143 1 PMID:30997498 -3.1.26.5 pre-trna escherichia coli 0.18 0.125 2 PMID:18330998 -3.1.26.5 pre-trna(au) escherichia coli 0.12 0.12 1 PMID:36045135 -3.1.26.5 pre-trna(au-d3) escherichia coli 0.261 0.261 1 PMID:36045135 -3.1.26.5 pre-trna(au-t5) escherichia coli 0.025 0.025 1 PMID:36045135 -3.1.26.5 pre-trna(au-t5d3) escherichia coli 0.06 0.06 1 PMID:36045135 -3.1.26.5 pre-trna(gg) escherichia coli 0.07 0.07 1 PMID:36045135 -3.1.26.5 pre-trna(gg-d3) escherichia coli 0.048 0.048 1 PMID:36045135 -3.1.26.5 pre-trna-asp arabidopsis thaliana 0.03 0.03 1 PMID:25817998 -3.1.26.5 pre-trna-cys arabidopsis thaliana 0.06 0.06 1 PMID:25817998 -3.1.26.5 pre-trna-tyr saccharomyces cerevisiae 0.08 0.0785 2 PMID:19095620 -3.1.26.5 pre-trnaasp bacillus subtilis 0.09 0.055 2 PMID:8643411 -3.1.26.5 pre-trnathr(agt) saccharomyces cerevisiae 0.667 0.35000000000000003 2 PMID:37074161 -3.1.26.5 pre-trnatyr methanococcus maripaludis 1.05 0.61 2 PMID:20675586 -3.1.26.5 pre-trnatyr prochlorothrix hollandica 0.107 0.107 1 PMID:9654127 -3.1.26.5 pre-trnatyr pyrococcus horikoshii 0.009 0.009 1 PMID:21512217 -3.1.26.5 pre-trnatyr saccharomyces cerevisiae 1.3 1.3 1 PMID:12045094 -3.1.26.5 ptrnatyr pyrococcus furiosus 0.1917 0.08415 4 PMID:17053064 -3.1.26.5 rnase p riboswitch a arabidopsis thaliana 0.0138 0.01165 2 PMID:35022261 -3.1.26.5 trna precursor bacillus subtilis 6.0 6.0 1 PMID:12045094 -3.1.26.5 trna precursor methanocaldococcus jannaschii 0.88 0.88 1 PMID:11592398 -3.1.26.5 trna precursor methanothermobacter thermautotrophicus 0.57 0.57 1 PMID:11592398 -3.1.26.5 trna precursor saccharomyces cerevisiae 1.3 1.3 1 PMID:11241345 -3.1.26.5 trnaphe (g+1) precursor spinacia oleracea 0.003 0.00175 2 PMID:10786845 -3.1.26.5 trnatyr precursor thermotoga maritima 0.14 0.14 1 PMID:11160919 -3.1.26.6 poly(a) gallus gallus 28.3 28.3 1 PMID:1009929 -3.1.26.8 artificial 5s rrna precursor bacillus subtilis 0.00667 0.00667 1 PMID:6432798 -3.1.26.8 artificial 5s rrna precursor substrate in complex with bl16 subunit bacillus subtilis 0.0567 0.0567 1 PMID:6432798 -3.1.3.1 2'-[2-benzthiazole]-6'-hydroxybenzthiazole phosphate escherichia coli 33.0 33.0 1 * -3.1.3.1 4-nitrophenyl phosphate anabaena sp. 29.9 29.9 1 PMID:20632947 -3.1.3.1 4-nitrophenyl phosphate antarctic bacterium tab5 236.0 236.0 1 PMID:18411226 -3.1.3.1 4-nitrophenyl phosphate bacillus licheniformis 16.0 16.0 1 * -3.1.3.1 4-nitrophenyl phosphate bos taurus 2250.0 186.65 24 PMID:15559981;PMID:22112405;PMID:23617076 -3.1.3.1 4-nitrophenyl phosphate cobetia marina 28300.0 13855.0 4 PMID:25260971 -3.1.3.1 4-nitrophenyl phosphate dioszegia sp. 1400.0 1400.0 2 PMID:29312954 -3.1.3.1 4-nitrophenyl phosphate escherichia coli 378.0 61.84 13 PMID:11099386;PMID:12707276;PMID:16859742;PMID:18627128;PMID:20087689;PMID:22851015;PMID:25902402 -3.1.3.1 4-nitrophenyl phosphate homo sapiens 971.0 675.0 2 PMID:11857742;PMID:18422967 -3.1.3.1 4-nitrophenyl phosphate pandalus borealis 16230.0 155.7 7 PMID:15559981 -3.1.3.1 4-nitrophenyl phosphate penaeus merguiensis 95.0 95.0 1 * -3.1.3.1 4-nitrophenyl phosphate shewanella sp. t3-3 7000.0 7000.0 1 PMID:28756743 -3.1.3.1 4-nitrophenyl phosphate sphingobium sp. tcm1 1270.0 1270.0 1 PMID:31832710 -3.1.3.1 4-nitrophenyl phosphate thermotoga maritima 100.0 58.0 2 PMID:11910033 -3.1.3.1 4-nitrophenyl phosphate thermus sp. ntu-237 6.08 6.08 1 * -3.1.3.1 4-nitrophenyl phosphate thermus yunnanensis 1130.0 603.0 2 PMID:15955749 -3.1.3.1 4-nitrophenyl phosphate vibrio sp. 2086.0 1218.0 2 PMID:10862903;PMID:17493882 -3.1.3.1 4-nitrophenyl phosphate vibrio sp. g15-21 356.0 293.5 2 PMID:36194497 -3.1.3.1 4-nitrophenyl phosphate vibrio splendidus 302.0 102.0 7 PMID:27043172;PMID:28829580 -3.1.3.1 diphosphate homo sapiens 244.0 244.0 1 PMID:11857742 -3.1.3.1 o-phosphoserine burkholderia cenocepacia 48.3 48.3 1 PMID:19376213 -3.1.3.1 o-phosphotyrosine burkholderia cenocepacia 138.1 138.1 1 PMID:19376213 -3.1.3.1 p-nitrophenyl phosphate burkholderia cenocepacia 147.9 147.9 1 PMID:19376213 -3.1.3.1 p-nitrophenyl phosphate escherichia coli 80.5 44.5 3 PMID:18067583;PMID:7703848 -3.1.3.1 p-nitrophenyl phosphate vibrio sp. 1580.0 1580.0 1 PMID:18067583 -3.1.3.1 phosphoenolpyruvate burkholderia cenocepacia 14.1 14.1 1 PMID:19376213 -3.1.3.1 pyridoxal 5'-phosphate homo sapiens 92.0 92.0 1 PMID:11857742 -3.1.3.10 adp pholiota microspora 0.0035 0.0035 1 PMID:9972248 -3.1.3.10 d-fructose 1-phosphate enterobacter cloacae 111.0 111.0 1 PMID:16193276 -3.1.3.10 d-fructose 1-phosphate escherichia coli 95.0 95.0 1 PMID:12782623 -3.1.3.10 d-fructose 6-phosphate enterobacter cloacae 105.0 105.0 1 PMID:16193276 -3.1.3.10 d-glucose 1-phosphate enterobacter cloacae 145.0 145.0 1 PMID:16193276 -3.1.3.10 d-glucose 1-phosphate escherichia coli 117.0 117.0 1 PMID:12782623 -3.1.3.10 d-glucose 6-phosphate enterobacter cloacae 109.0 109.0 1 PMID:16193276 -3.1.3.10 d-glucose 6-phosphate escherichia coli 82.0 82.0 1 PMID:12782623 -3.1.3.10 d-ribose 5-phosphate escherichia coli 42.0 42.0 1 PMID:12782623 -3.1.3.10 fructose 1-phosphate pholiota microspora 0.00217 0.00217 1 PMID:9972248 -3.1.3.10 fructose 6-phosphate pholiota microspora 0.00167 0.00167 1 PMID:9972248 -3.1.3.10 galactose 1-phosphate pholiota microspora 0.0348 0.0348 1 PMID:9972248 -3.1.3.10 glucose 1-phosphate pholiota microspora 0.0393 0.0393 1 PMID:9972248 -3.1.3.10 myo-inositol hexakisphosphate enterobacter cloacae 24.0 24.0 1 PMID:16193276 -3.1.3.10 myo-inositol hexakisphosphate escherichia coli 12.0 12.0 1 PMID:12782623 -3.1.3.10 myo-inositol hexakisphosphate pantoea agglomerans 20.5 14.25 2 * -3.1.3.10 p-nitrophenyl phosphate enterobacter cloacae 30.0 30.0 1 PMID:16193276 -3.1.3.10 p-nitrophenyl phosphate escherichia coli 6.0 6.0 1 PMID:12782623 -3.1.3.10 phosphoenolpyruvate pholiota microspora 0.000667 0.000667 1 PMID:9972248 -3.1.3.10 ribose 5-phosphate pholiota microspora 0.0005 0.0005 1 PMID:9972248 -3.1.3.102 fmn arabidopsis thaliana 0.822 0.706 2 PMID:16183635;PMID:22002057 -3.1.3.102 fmn escherichia coli 9.4 7.95 2 PMID:16990279 -3.1.3.103 2-dehydro-3-deoxy-d-manno-octulosonic acid 8-phosphate bacteroides thetaiotaomicron 0.06 0.06 1 PMID:18804026 -3.1.3.103 3-deoxy-d-glycero-d-galacto-nononate 9-phosphate bacteroides thetaiotaomicron 1.2 1.2 2 PMID:18804026;PMID:18986982 -3.1.3.103 n-acetylneuraminic acid 9-phosphate bacteroides thetaiotaomicron 0.73 0.73 1 PMID:18804026 -3.1.3.104 5-amino-6-(5-phospho-d-ribitylamino)uracil arabidopsis thaliana 2.8 1.4649999999999999 2 PMID:27490826 -3.1.3.104 5-amino-6-(5-phospho-d-ribitylamino)uracil bacillus subtilis 0.88 0.88 1 PMID:32040605 -3.1.3.104 5-amino-6-(5-phospho-d-ribitylamino)uracil bacteroides thetaiotaomicron 0.016 0.016 1 * -3.1.3.104 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate bacillus subtilis 11.28 11.28 1 PMID:32040605 -3.1.3.104 amp bacillus subtilis 28.16 28.16 1 PMID:32040605 -3.1.3.104 cmp bacillus subtilis 39.18 39.18 1 PMID:32040605 -3.1.3.104 d-ribitol 1-phosphate bacteroides thetaiotaomicron 1.8 1.8 1 * -3.1.3.104 d-ribitol 5-phosphate bacteroides thetaiotaomicron 1.5 1.5 1 * -3.1.3.104 damp bacillus subtilis 26.25 26.25 1 PMID:32040605 -3.1.3.104 dgmp bacillus subtilis 13.8 13.8 1 PMID:32040605 -3.1.3.104 fmn arabidopsis thaliana 0.59 0.59 1 PMID:27490826 -3.1.3.104 fmn bacillus subtilis 22.97 22.97 1 PMID:32040605 -3.1.3.104 gmp bacillus subtilis 21.26 21.26 1 PMID:32040605 -3.1.3.104 imp bacillus subtilis 26.34 26.34 1 PMID:32040605 -3.1.3.104 xmp bacillus subtilis 37.49 37.49 1 PMID:32040605 -3.1.3.105 n-acetyl-d-muramate 6-phosphate pseudomonas putida 0.88 0.88 2 PMID:28351914;PMID:28505548 -3.1.3.106 1-arachidonoyl-2-lyso-sn-glycerol 3-phosphate homo sapiens 250.0 250.0 1 PMID:22387545 -3.1.3.106 1-myristoyl-sn-glycerol 3-phosphate homo sapiens 354.0 354.0 1 PMID:22387545 -3.1.3.106 1-oleoyl-2-lyso-sn-glycerol 3-phosphate homo sapiens 177.0 177.0 1 PMID:22387545 -3.1.3.106 1-stearyl-2-lyso-sn-glycerol 3-phosphate homo sapiens 125.0 125.0 1 PMID:22387545 -3.1.3.108 nadp+ archaeoglobus fulgidus 26.3 26.3 1 PMID:18391451 -3.1.3.108 nadp+ methanocaldococcus jannaschii 212.0 108.5 2 PMID:18391451 -3.1.3.108 nadph archaeoglobus fulgidus 40.3 40.3 1 PMID:18391451 -3.1.3.108 nadph methanocaldococcus jannaschii 236.0 121.45 2 PMID:18391451 -3.1.3.108 nadph mus musculus 15.6 15.6 1 PMID:31879354 -3.1.3.11 beta-d-glucose 1,6-bisphosphate lactobacillus delbrueckii subsp. lactis 175.0 175.0 1 PMID:19154134 -3.1.3.11 beta-d-glucose 1,6-bisphosphate neisseria meningitidis 20.0 20.0 1 PMID:19154134 -3.1.3.11 d-fructose 1,6-bisphosphate archaeoglobus fulgidus 212.0 212.0 1 PMID:18391451 -3.1.3.11 d-fructose 1,6-bisphosphate bacillus methanolicus 3.9 2.55 2 PMID:24013630 -3.1.3.11 d-fructose 1,6-bisphosphate bos taurus 14.8 7.675000000000001 2 PMID:11126748 -3.1.3.11 d-fructose 1,6-bisphosphate escherichia coli 26.0 20.0 7 PMID:11825604;PMID:14530289;PMID:15767255;PMID:17314096;PMID:19073594 -3.1.3.11 d-fructose 1,6-bisphosphate euglena gracilis 26.4 1.08 6 PMID:25906744;PMID:26214137 -3.1.3.11 d-fructose 1,6-bisphosphate francisella tularensis 0.55 0.55 1 PMID:33135671 -3.1.3.11 d-fructose 1,6-bisphosphate homo sapiens 23.5 21.7 5 PMID:16213487;PMID:18214967;PMID:24146906 -3.1.3.11 d-fructose 1,6-bisphosphate leishmania major 8.0 8.0 1 PMID:28882541 -3.1.3.11 d-fructose 1,6-bisphosphate methanocaldococcus jannaschii 212.0 110.2 2 PMID:18391451 -3.1.3.11 d-fructose 1,6-bisphosphate mycobacterium tuberculosis 2.1 2.1 1 * -3.1.3.11 d-fructose 1,6-bisphosphate pyrococcus furiosus 18.0 9.15 2 PMID:12029059 -3.1.3.11 d-fructose 1,6-bisphosphate saccharomyces cerevisiae 4.9 4.9 1 PMID:20427268 -3.1.3.11 d-fructose 1,6-bisphosphate salmonella enterica 24.3 24.3 1 PMID:16987812 -3.1.3.11 d-fructose 1,6-bisphosphate sulfurisphaera tokodaii 0.62 0.62 1 PMID:21983966 -3.1.3.11 d-fructose 1,6-bisphosphate sus scrofa 23.0 21.0 7 PMID:10896931;PMID:11825604;PMID:14978036;PMID:17894826;PMID:30683805 -3.1.3.11 d-fructose 1,6-bisphosphate sus scrofa domesticus 16.1 16.1 1 PMID:11126748 -3.1.3.11 d-fructose 1,6-bisphosphate synechocystis sp. 10.5 10.5 1 PMID:24286336 -3.1.3.11 d-fructose 1,6-bisphosphate thermococcus kodakarensis 17.0 17.0 1 PMID:12065581 -3.1.3.11 d-fructose 1,6-bisphosphate thermotoga maritima 58.7 33.635000000000005 2 * -3.1.3.11 d-fructose 1,6-bisphosphate triticum aestivum 22.9 22.9 1 PMID:10910732 -3.1.3.11 d-fructose-1,6-bisphosphate corynebacterium glutamicum 3.2 3.2 1 PMID:12904832 -3.1.3.11 d-fructose-1,6-bisphosphate sus scrofa 22.0 22.0 1 PMID:11854289 -3.1.3.11 fructose 1,6-bisphosphate escherichia coli 2.5 2.5 1 PMID:19073594 -3.1.3.11 fructose 1,6-diphosphate sus scrofa 21.0 18.0 4 PMID:8969189;PMID:9334199;PMID:9651342 -3.1.3.112 dadp priestia megaterium 0.0026 0.0026 1 PMID:27849620 -3.1.3.112 damp priestia megaterium 0.0037 0.0037 1 PMID:27849620 -3.1.3.112 datp priestia megaterium 0.022 0.022 1 PMID:27849620 -3.1.3.112 oxetanocin a 5'-phosphate priestia megaterium 0.0012 0.0012 1 PMID:27849620 -3.1.3.112 oxetanocin a diphosphate priestia megaterium 0.0029 0.0029 1 PMID:27849620 -3.1.3.112 oxetanocin a triphosphate priestia megaterium 0.0045 0.0045 1 PMID:27849620 -3.1.3.12 alpha,alpha-trehalose 6-phosphate acinetobacter baumannii 0.004 0.004 1 PMID:33171283 -3.1.3.12 alpha,alpha-trehalose 6-phosphate burkholderia pseudomallei 2.62 2.62 1 PMID:31973820 -3.1.3.12 alpha,alpha-trehalose 6-phosphate corynebacterium diphtheriae 5.2 5.2 1 PMID:33171283 -3.1.3.12 alpha,alpha-trehalose 6-phosphate stenotrophomonas maltophilia 0.23 0.23 1 PMID:33171283 -3.1.3.12 alpha,alpha-trehalose 6-phosphate stutzerimonas stutzeri 22.0 22.0 1 PMID:33171283 -3.1.3.12 trehalose 6-phosphate arthrobacter sp. 14.79 3.94 5 PMID:22806197 -3.1.3.12 trehalose 6-phosphate brugia malayi 24.0 24.0 1 PMID:24992307 -3.1.3.12 trehalose 6-phosphate caenorhabditis elegans 8.0 8.0 1 PMID:16197937 -3.1.3.12 trehalose 6-phosphate escherichia coli 14.6 14.45 2 PMID:10831428 -3.1.3.12 trehalose 6-phosphate oryza sativa 6.52 3.5349999999999997 2 PMID:17257172 -3.1.3.12 trehalose 6-phosphate oryza sativa japonica group 13.4 13.4 1 PMID:17257172 -3.1.3.12 trehalose 6-phosphate thermoplasma acidophilum 10.0 10.0 1 PMID:16815921 -3.1.3.15 amp thermococcus onnurineus 29.0 29.0 1 PMID:18223080 -3.1.3.15 d-fructose 6-phosphate thermococcus onnurineus 11.0 11.0 1 PMID:18223080 -3.1.3.15 l-histidinol 1-phosphate arabidopsis thaliana 1.3 1.3 1 PMID:25620968 -3.1.3.15 l-histidinol phosphate corynebacterium glutamicum 1.04 0.5265 2 PMID:28720084 -3.1.3.15 l-histidinol phosphate escherichia coli 2140.0 1185.0 4 PMID:16966333 -3.1.3.15 l-histidinol phosphate lactococcus lactis subsp. lactis 174.0 174.0 1 PMID:23327428 -3.1.3.15 l-histidinol phosphate medicago truncatula 3.6 3.6 1 PMID:26994138 -3.1.3.15 l-histidinol phosphate mycobacterium tuberculosis 0.99 0.99 1 PMID:29752410 -3.1.3.15 l-histidinol phosphate thermococcus onnurineus 420.0 305.0 4 PMID:18223080 -3.1.3.15 l-histidinol phosphate thermus thermophilus 0.93 0.93 1 PMID:17929834 -3.1.3.15 l-phosphoserine thermococcus onnurineus 14.0 14.0 1 PMID:18223080 -3.1.3.16 4-nitrophenyl phosphate enterococcus faecium 20.0 10.1 2 PMID:25006233 -3.1.3.16 4-nitrophenyl phosphate homo sapiens 13.8 13.8 1 PMID:18992256 -3.1.3.16 4-nitrophenyl phosphate salmonella enterica 7.4 7.4 1 PMID:15817783 -3.1.3.16 6,8-difluoro-4-methylumbelliferyl phosphate thermococcus kodakarensis 30.0 17.37 2 PMID:29791483 -3.1.3.16 [alpha-casein]-serine/threonine phosphate mycoplasmopsis synoviae 1.3 1.3 1 PMID:25370051 -3.1.3.16 aaaptva homo sapiens 1.05 1.05 1 PMID:25012655 -3.1.3.16 agpalpspvppv homo sapiens 1.31 1.31 1 PMID:25012655 -3.1.3.16 alsagpsneylr homo sapiens 0.65 0.65 1 PMID:25012655 -3.1.3.16 asqeppspaasa homo sapiens 0.62 0.62 1 PMID:25012655 -3.1.3.16 ddaptva homo sapiens 1.3 1.3 1 PMID:25012655 -3.1.3.16 endptinasl homo sapiens 1.2 1.2 1 PMID:25012655 -3.1.3.16 erk5 homo sapiens 2.4 2.4 1 PMID:15807522 -3.1.3.16 esemeptpsain homo sapiens 0.39 0.39 1 PMID:25012655 -3.1.3.16 hsapppspeekd homo sapiens 0.86 0.86 1 PMID:25012655 -3.1.3.16 nfedhpsappsp homo sapiens 1.33 1.33 1 PMID:25012655 -3.1.3.16 npcteptftgtl homo sapiens 1.16 1.16 1 PMID:25012655 -3.1.3.16 p-nitrophenyl phosphate lambdavirus lambda 1100.0 490.0 7 PMID:11467953 -3.1.3.16 p-nitrophenyl phosphate saccharomyces cerevisiae 0.78 0.45 2 PMID:16442612 -3.1.3.16 pvartpsplqtp homo sapiens 0.64 0.64 1 PMID:25012655 -3.1.3.16 rgrgspsvgggs homo sapiens 0.03 0.03 1 PMID:25012655 -3.1.3.16 rra(pt)va mycoplasmopsis synoviae 0.09 0.09 1 PMID:25370051 -3.1.3.16 rrapsva homo sapiens 0.93 0.93 1 PMID:25012655 -3.1.3.16 rraptva homo sapiens 170.0 2.0 3 PMID:11415453;PMID:25012655 -3.1.3.16 rras(p)va salmonella enterica 0.9 0.9 1 PMID:15817783 -3.1.3.16 rrat(p)va salmonella enterica 2.5 2.5 1 PMID:15817783 -3.1.3.16 serine/threonine-phosphorylated myelin basic protein salmonella enterica 1.1 1.1 1 PMID:15817783 -3.1.3.16 sqlhiptpgtay homo sapiens 0.4 0.4 1 PMID:25012655 -3.1.3.16 tyrosine-phosphorylated myelin basic protein salmonella enterica 0.1 0.1 1 PMID:15817783 -3.1.3.16 varklpsareqr homo sapiens 0.86 0.86 1 PMID:25012655 -3.1.3.16 whladpspavng homo sapiens 1.03 1.03 1 PMID:25012655 -3.1.3.16 ylrsipslpvpv homo sapiens 0.48 0.48 1 PMID:25012655 -3.1.3.17 histone bos taurus 3.3 3.3 1 PMID:217307 -3.1.3.17 phosphorylase a oryctolagus cuniculus 5.2 5.2 1 PMID:240850 -3.1.3.18 2-phospho-l-lactate plasmodium berghei 67.34 67.34 2 PMID:30700551 -3.1.3.18 2-phosphoglycolate escherichia coli 94.0 94.0 2 PMID:13129953 -3.1.3.18 2-phosphoglycolate homo sapiens 19.0 19.0 1 PMID:14555659 -3.1.3.18 2-phosphoglycolate mus musculus 2.13 2.13 1 PMID:27179418 -3.1.3.18 2-phosphoglycolate plasmodium berghei 75.15 75.15 2 PMID:30700551 -3.1.3.18 2-phosphoglycolate spinacia oleracea 292.0 292.0 1 PMID:14555659 -3.1.3.18 2-phosphoglycolate thermoplasma acidophilum 8.26 4.385 2 PMID:14555659 -3.1.3.18 diphosphate thermoplasma acidophilum 6.08 4.8 3 PMID:14555659 -3.1.3.18 glycerol 2-phosphate plasmodium berghei 10.18 10.18 2 PMID:30700551 -3.1.3.18 p-nitrophenyl phosphate thermoplasma acidophilum 4.8 2.69 2 PMID:14555659 -3.1.3.18 phosphoglycolate thermoplasma acidophilum 8.26 8.26 1 PMID:14555659 -3.1.3.2 1-naphthyl phosphate blastobotrys adeninivorans 5282.0 5282.0 1 PMID:17016743 -3.1.3.2 2'-amp haemophilus influenzae 0.11 0.11 1 PMID:20934434 -3.1.3.2 2'-amp pasteurella multocida 0.13 0.13 1 PMID:21371420 -3.1.3.2 2-glycerophosphate glycine max 125.0 125.0 1 PMID:2829734 -3.1.3.2 3'-amp haemophilus influenzae 0.1 0.1 1 PMID:20934434 -3.1.3.2 3'-amp homo sapiens 248.0 248.0 1 * -3.1.3.2 3'-amp legionella pneumophila 3.0 3.0 1 PMID:26380880 -3.1.3.2 3'-amp pasteurella multocida 0.19 0.19 1 PMID:21371420 -3.1.3.2 3'-dcmp escherichia coli 101.0 101.0 1 PMID:16297670 -3.1.3.2 3-indoxyl phosphate blastobotrys adeninivorans 1056.0 1056.0 1 PMID:17016743 -3.1.3.2 4-methylumbelliferyl phosphate homo sapiens 121.0 121.0 1 PMID:2775236 -3.1.3.2 4-nitrophenyl phosphate acinetobacter baumannii 4.8 4.8 1 PMID:34077475 -3.1.3.2 4-nitrophenyl phosphate arabidopsis thaliana 161.9 161.9 1 PMID:19633233 -3.1.3.2 4-nitrophenyl phosphate euphorbia characias 790.0 790.0 1 PMID:21639850 -3.1.3.2 4-nitrophenyl phosphate francisella tularensis 4.48 4.48 1 PMID:21042033 -3.1.3.2 4-nitrophenyl phosphate homo sapiens 240.0 34.3 8 PMID:15955057;PMID:16620768 -3.1.3.2 4-nitrophenyl phosphate legionella pneumophila 16.1 16.1 1 PMID:26380880 -3.1.3.2 4-nitrophenyl phosphate mycolicibacterium smegmatis 0.33 0.20500000000000002 2 PMID:25986906 -3.1.3.2 4-nitrophenyl phosphate nelumbo nucifera 6.7 6.7 1 PMID:25887488 -3.1.3.2 4-nitrophenyl phosphate opuntia megacantha 9.6 9.6 1 PMID:32454111 -3.1.3.2 4-nitrophenyl phosphate pasteurella multocida 6.2 6.2 1 PMID:21371420 -3.1.3.2 4-nitrophenyl phosphate prevotella intermedia 26.0 26.0 1 PMID:12485613 -3.1.3.2 4-nitrophenyl phosphate sphingobium sp. rsms 15.6 15.6 1 PMID:35242619 -3.1.3.2 5'-amp haemophilus influenzae 0.07 0.07 1 PMID:20934434 -3.1.3.2 5'-amp homo sapiens 225.0 225.0 1 * -3.1.3.2 5'-amp legionella pneumophila 2.4 2.4 1 PMID:26380880 -3.1.3.2 5'-amp pasteurella multocida 0.18 0.18 1 PMID:21371420 -3.1.3.2 5'-gmp homo sapiens 244.0 244.0 1 * -3.1.3.2 5'-imp homo sapiens 254.0 254.0 1 * -3.1.3.2 adp blastobotrys adeninivorans 2676.0 2676.0 1 PMID:17016743 -3.1.3.2 adp homo sapiens 73.0 73.0 1 PMID:2775236 -3.1.3.2 adp sphingobium sp. rsms 34.2 34.2 1 PMID:35242619 -3.1.3.2 alpha-naphthyl phosphate homo sapiens 53.0 53.0 1 PMID:2775236 -3.1.3.2 amp blastobotrys adeninivorans 845.0 845.0 1 PMID:17016743 -3.1.3.2 amp ipomoea batatas 50.0 47.5 2 PMID:12913313 -3.1.3.2 amp sphingobium sp. rsms 29.3 29.3 1 PMID:35242619 -3.1.3.2 atp glycine max 188.0 188.0 1 PMID:2829734 -3.1.3.2 atp homo sapiens 119.0 119.0 1 PMID:2775236 -3.1.3.2 atp ipomoea batatas 155.0 155.0 1 PMID:12913313 -3.1.3.2 atp nicotiana tabacum 133.2 133.2 1 PMID:18762304 -3.1.3.2 atp sphingobium sp. rsms 17.4 17.4 1 PMID:35242619 -3.1.3.2 bis(p-nitrophenyl) phosphate glycine max 700.0 700.0 1 PMID:2829734 -3.1.3.2 cdp homo sapiens 58.0 58.0 1 PMID:2775236 -3.1.3.2 ctp homo sapiens 93.0 93.0 1 PMID:2775236 -3.1.3.2 d-fructose 6-phosphate ipomoea batatas 171.0 171.0 1 PMID:12913313 -3.1.3.2 d-glucose 6-phosphate blastobotrys adeninivorans 2462.0 2462.0 1 PMID:17016743 -3.1.3.2 d-glucose 6-phosphate ipomoea batatas 218.0 218.0 1 PMID:12913313 -3.1.3.2 d-sucrose 6-phosphate ipomoea batatas 35.0 35.0 1 PMID:12913313 -3.1.3.2 dade(py)lipqqg nicotiana tabacum 26.7 26.7 1 PMID:18762304 -3.1.3.2 eey(p)aa sus scrofa 79.0 72.0 2 PMID:15047187 -3.1.3.2 end(py)inasl nicotiana tabacum 32.8 32.8 1 PMID:18762304 -3.1.3.2 fmoc-aay(p)aa sus scrofa 100.0 100.0 1 PMID:15047187 -3.1.3.2 fmoc-eey(p)aa sus scrofa 120.0 77.5 2 PMID:15047187 -3.1.3.2 fmoc-ey(p)a sus scrofa 31.0 28.0 2 PMID:15047187 -3.1.3.2 fmoc-kkay(p)aa sus scrofa 170.0 170.0 1 PMID:15047187 -3.1.3.2 gdp homo sapiens 86.0 86.0 1 PMID:2775236 -3.1.3.2 glycerol 2-phosphate blastobotrys adeninivorans 1831.0 1831.0 1 PMID:17016743 -3.1.3.2 gtp homo sapiens 113.0 113.0 1 PMID:2775236 -3.1.3.2 idp nicotiana tabacum 60.4 60.4 1 PMID:18762304 -3.1.3.2 methyl-p-nitrophenyl phosphate phaseolus vulgaris 542.0 542.0 1 PMID:17636903 -3.1.3.2 methyl-p-nitrophenyl phosphate sus scrofa 542.0 542.0 1 PMID:17636903 -3.1.3.2 methylphosphate phaseolus vulgaris 20.0 20.0 1 PMID:17636903 -3.1.3.2 methylphosphate sus scrofa 17.0 17.0 1 PMID:17636903 -3.1.3.2 monobutyl phosphate sphingobium sp. rsms 68.1 68.1 1 PMID:35242619 -3.1.3.2 myo-inositol hexakisphosphate arabidopsis thaliana 8.85 8.85 1 PMID:19633233 -3.1.3.2 na2h2p2o7 glycine max 232.0 232.0 1 PMID:2829734 -3.1.3.2 nadp ipomoea batatas 295.0 295.0 1 PMID:12913313 -3.1.3.2 nicotinamide mononucleotide haemophilus influenzae 0.52 0.52 1 PMID:20934434 -3.1.3.2 nmn pasteurella multocida 4.4 4.4 1 PMID:21371420 -3.1.3.2 p-nitrophenyl phosphate arabidopsis thaliana 161.9 161.9 1 PMID:19633233 -3.1.3.2 p-nitrophenyl phosphate blastobotrys adeninivorans 40850.0 40850.0 1 PMID:17016743 -3.1.3.2 p-nitrophenyl phosphate glycine max 430.0 430.0 1 PMID:2829734 -3.1.3.2 p-nitrophenyl phosphate homo sapiens 198.0 198.0 1 PMID:2775236 -3.1.3.2 p-nitrophenyl phosphate ipomoea batatas 531.0 531.0 1 PMID:12913313 -3.1.3.2 p-nitrophenyl phosphate nicotiana tabacum 125.0 125.0 1 PMID:18762304 -3.1.3.2 p-nitrophenyl phosphate phaseolus vulgaris 850.0 850.0 1 PMID:17636903 -3.1.3.2 p-nitrophenyl phosphate salmonella enterica subsp. enterica serovar typhimurium 22.25 16.47 4 PMID:16901752 -3.1.3.2 p-nitrophenyl phosphate sus scrofa 470.0 470.0 1 PMID:17636903 -3.1.3.2 phenolphthalein diphosphate homo sapiens 109.0 109.0 1 PMID:2775236 -3.1.3.2 phenyl phosphate glycine max 219.0 219.0 1 PMID:2829734 -3.1.3.2 phenyl phosphate homo sapiens 62.0 62.0 1 PMID:2775236 -3.1.3.2 phosphocholine francisella tularensis 33.24 33.24 1 PMID:21042033 -3.1.3.2 phosphoenolpyruvate arabidopsis thaliana 198.6 198.3 2 PMID:19633233 -3.1.3.2 phosphoenolpyruvate homo sapiens 2.0 2.0 1 PMID:2775236 -3.1.3.2 phosphoserine nicotiana tabacum 26.8 26.8 1 PMID:18762304 -3.1.3.2 phosphotyrosine nicotiana tabacum 62.4 62.4 1 PMID:18762304 -3.1.3.2 phytic acid blastobotrys adeninivorans 915.0 915.0 1 PMID:17016743 -3.1.3.2 pyridoxal 5'-phosphate blastobotrys adeninivorans 1901.0 1901.0 1 PMID:17016743 -3.1.3.2 rra(pt)va nicotiana tabacum 2.0 2.0 1 PMID:18762304 -3.1.3.2 sodium diphosphate blastobotrys adeninivorans 2042.0 2042.0 1 PMID:17016743 -3.1.3.2 sodium phytate arabidopsis thaliana 8.85 8.85 1 PMID:19633233 -3.1.3.2 tdp homo sapiens 69.0 69.0 1 PMID:2775236 -3.1.3.2 thiamine diphosphate francisella tularensis 0.48 0.48 1 PMID:21042033 -3.1.3.2 thiamine monophosphate francisella tularensis 4.85 4.85 1 PMID:21042033 -3.1.3.2 ttp homo sapiens 107.0 107.0 1 PMID:2775236 -3.1.3.2 udp homo sapiens 79.0 79.0 1 PMID:2775236 -3.1.3.2 utp homo sapiens 119.0 119.0 1 PMID:2775236 -3.1.3.21 4-nitrophenyl phosphate mycobacterium tuberculosis 1.0 1.0 1 PMID:23801751 -3.1.3.21 alpha-glycerolphosphate saccharomyces cerevisiae 833.0 833.0 1 PMID:13405892 -3.1.3.21 d-ribulose 5-phosphate mycobacterium tuberculosis 0.18 0.18 1 PMID:23801751 -3.1.3.21 dl-glycerol 3-phosphate corynebacterium glutamicum 30.3 30.3 1 PMID:22353596 -3.1.3.21 dl-glycerol 3-phosphate escherichia coli 160.0 160.0 1 PMID:17113805 -3.1.3.21 dl-glycerol 3-phosphate mycobacterium tuberculosis 0.77 0.77 1 PMID:23801751 -3.1.3.21 glycerol 2-phosphate mycobacterium tuberculosis 0.18 0.18 1 PMID:23801751 -3.1.3.21 l-glycerol 3-phosphate corynebacterium glutamicum 1.7 1.7 1 PMID:22353596 -3.1.3.21 l-glycerol 3-phosphate mycobacterium tuberculosis 0.02 0.02 1 PMID:23801751 -3.1.3.22 d-mannitol 1-phosphate acinetobacter baumannii 152.88 152.88 1 PMID:35363566 -3.1.3.22 d-mannitol 1-phosphate ectocarpus siliculosus 0.015 0.015 1 PMID:24323504 -3.1.3.23 2-deoxy-d-glucose 6-phosphate arabidopsis thaliana 33.0 33.0 1 PMID:24915748 -3.1.3.23 4-nitrophenyl phosphate bacillus subtilis 0.012 0.012 1 PMID:21575135 -3.1.3.23 d-arabinose 5-phosphate bacillus subtilis 2.92 2.92 1 PMID:21575135 -3.1.3.23 d-fructose 1,6-bisphosphate bacillus subtilis 1.49 1.49 1 PMID:21575135 -3.1.3.23 d-fructose 6-phosphate arabidopsis thaliana 19.0 19.0 1 PMID:24915748 -3.1.3.23 d-fructose 6-phosphate bacillus subtilis 2.817 2.817 1 PMID:21575135 -3.1.3.23 d-fructose 6-phosphate pseudomonas fluorescens 9.6 9.6 1 PMID:27836849 -3.1.3.23 d-galactose 1-phosphate bacillus subtilis 4.28 4.28 1 PMID:21575135 -3.1.3.23 d-glucose 6-phosphate arabidopsis thaliana 24.0 24.0 1 PMID:24915748 -3.1.3.23 d-glucose 6-phosphate bacillus subtilis 2.49 2.49 1 PMID:21575135 -3.1.3.23 d-glucose 6-phosphate pseudomonas fluorescens 11.4 11.4 1 PMID:27836849 -3.1.3.23 d-mannose 6-phosphate arabidopsis thaliana 32.0 32.0 1 PMID:24915748 -3.1.3.23 d-ribose 5-phosphate arabidopsis thaliana 39.0 39.0 1 PMID:24915748 -3.1.3.23 d-xylulose 5-phosphate bacillus subtilis 2.75 2.75 1 PMID:21575135 -3.1.3.23 dl-glycerol 3-phosphate arabidopsis thaliana 23.0 23.0 1 PMID:24915748 -3.1.3.24 sucrose 6-phosphate arabidopsis thaliana 67.8 35.699999999999996 2 PMID:27855180 -3.1.3.25 3,5-dideoxy-d-myo-inositol 1-phosphate archaeoglobus fulgidus 2.5 2.495 2 PMID:15563150;PMID:16519525 -3.1.3.25 3,5-dideoxy-d-myo-inositol 1-phosphate escherichia coli 4.0 4.0 1 PMID:15563150 -3.1.3.25 3,5-dideoxy-l-myo-inositol 1-phosphate archaeoglobus fulgidus 5.8 5.79 2 PMID:15563150;PMID:16519525 -3.1.3.25 3,5-dideoxy-l-myo-inositol 1-phosphate escherichia coli 4.4 4.4 1 PMID:15563150 -3.1.3.25 3-deoxy-d-myo-inositol 1-phosphate archaeoglobus fulgidus 3.9 3.9 1 PMID:15563150 -3.1.3.25 3-deoxy-d-myo-inositol 1-phosphate escherichia coli 4.4 4.4 1 PMID:15563150 -3.1.3.25 3-deoxy-l-myo-inositol 1-phosphate archaeoglobus fulgidus 3.2 3.2 1 PMID:15563150 -3.1.3.25 3-deoxy-l-myo-inositol 1-phosphate escherichia coli 5.6 5.6 1 PMID:15563150 -3.1.3.25 d-fructose 1,6-bisphosphate archaeoglobus fulgidus 2.7 2.7 1 PMID:11062561 -3.1.3.25 d-fructose 1,6-bisphosphate methanocaldococcus jannaschii 7.0 4.85 2 PMID:11062561 -3.1.3.25 d-fructose 1,6-bisphosphate thermotoga maritima 268.0 268.0 1 PMID:11062561 -3.1.3.25 d-galactose 1-phosphate arabidopsis thaliana 2.4 2.4 1 PMID:25620968 -3.1.3.25 d-myo-inositol 1-phosphate arabidopsis thaliana 0.6 0.6 1 PMID:25620968 -3.1.3.25 d-myo-inositol 1-phosphate archaeoglobus fulgidus 28.7 4.32 3 PMID:15563150;PMID:16519525;PMID:17616624 -3.1.3.25 d-myo-inositol 1-phosphate escherichia coli 4.4 2.4450000000000003 2 PMID:15563150;PMID:17652087 -3.1.3.25 d-myo-inositol 1-phosphate methanocaldococcus jannaschii 7.72 5.91 2 PMID:16519525;PMID:17616624 -3.1.3.25 d-myo-inositol 1-phosphate thermotoga maritima 104.0 104.0 1 PMID:16519525 -3.1.3.25 d-myo-inositol 3-phosphate archaeoglobus fulgidus 3.6 3.6 1 PMID:15563150 -3.1.3.25 d-myo-inositol 3-phosphate escherichia coli 1.4 1.4 1 PMID:15563150 -3.1.3.25 dl-myo-inositol 1-phosphate hordeum vulgare 1.29 1.29 1 PMID:18493722 -3.1.3.25 inositol 1,3-thiophosphate bos taurus 0.19 0.19 1 PMID:11882005 -3.1.3.25 inositol 3-phosphate bos taurus 0.48 0.48 1 PMID:11882005 -3.1.3.25 l-histidinol phosphate medicago truncatula 3.6 3.6 1 PMID:26994138 -3.1.3.25 l-myo-inositol 1-phosphate archaeoglobus fulgidus 3.64 3.62 2 PMID:15563150;PMID:16519525 -3.1.3.25 l-myo-inositol 1-phosphate escherichia coli 1.4 1.4 1 PMID:15563150 -3.1.3.25 l-myo-inositol 1-phosphate methanocaldococcus jannaschii 7.92 7.92 1 PMID:16519525 -3.1.3.25 l-myo-inositol 1-phosphate thermotoga maritima 16.6 16.6 1 PMID:16519525 -3.1.3.25 myo-inositol 1-phosphate archaeoglobus fulgidus 2.5 2.5 1 PMID:11062561 -3.1.3.25 myo-inositol 1-phosphate escherichia coli 6.5 6.5 1 PMID:11062561 -3.1.3.25 myo-inositol 1-phosphate methanocaldococcus jannaschii 4.2 2.85 2 PMID:11062561 -3.1.3.25 myo-inositol 1-phosphate mycobacterium tuberculosis 3.6 3.6 1 PMID:11914086 -3.1.3.25 myo-inositol 1-phosphate thermotoga maritima 207.0 207.0 1 PMID:11062561 -3.1.3.26 1-naphthyl phosphate avena sativa 305.0 305.0 1 * -3.1.3.26 2-naphthyl phosphate avena sativa 360.0 360.0 1 * -3.1.3.26 4-nitrophenyl phosphate aspergillus fumigatus 358000.0 357750.0 2 PMID:10679211 -3.1.3.26 4-nitrophenyl phosphate escherichia coli 3366.7 3366.7 1 PMID:33789740 -3.1.3.26 adp avena sativa 450.0 450.0 1 * -3.1.3.26 amp avena sativa 16.0 16.0 1 * -3.1.3.26 atp avena sativa 645.0 645.0 1 * -3.1.3.26 diphosphate avena sativa 943.0 943.0 1 * -3.1.3.26 fructose 1,6-diphosphate avena sativa 210.0 210.0 1 * -3.1.3.26 fructose 6-phosphate avena sativa 35.0 35.0 1 * -3.1.3.26 glucose 6-phosphate avena sativa 70.0 70.0 1 * -3.1.3.26 glycerol 2-phosphate avena sativa 102.0 102.0 1 * -3.1.3.26 gtp avena sativa 388.0 388.0 1 * -3.1.3.26 myo-inositol 1,2,3,4,5,6-hexakisphosphate escherichia coli 10209.0 10209.0 1 PMID:35683026 -3.1.3.26 myo-inositol hexakisphosphate aspergillus ficuum 348.0 348.0 3 PMID:10964658;PMID:11812011 -3.1.3.26 myo-inositol hexakisphosphate aspergillus fumigatus 412000.0 411700.0 3 PMID:10679211;PMID:10964658 -3.1.3.26 myo-inositol hexakisphosphate aspergillus japonicus 279.3 255.15 2 PMID:19025560 -3.1.3.26 myo-inositol hexakisphosphate aspergillus niger 300000.0 253.5 13 PMID:15776271;PMID:16751556;PMID:17450356;PMID:18399637;PMID:19025560 -3.1.3.26 myo-inositol hexakisphosphate avena sativa 356.0 356.0 1 * -3.1.3.26 myo-inositol hexakisphosphate bacillus sp. (in: firmicutes) 26.6 26.6 1 PMID:11594462 -3.1.3.26 myo-inositol hexakisphosphate burkholderia sp. a13(2014) 236.2 236.2 1 PMID:25833676 -3.1.3.26 myo-inositol hexakisphosphate debaryomyces castellii 59.2 55.2 2 PMID:18242101 -3.1.3.26 myo-inositol hexakisphosphate enterobacter sp. acss 1640.0 1640.0 1 PMID:27250653 -3.1.3.26 myo-inositol hexakisphosphate escherichia coli 6931.0 1512.0 6 PMID:17805950;PMID:18399637;PMID:18443782;PMID:8387749 -3.1.3.26 myo-inositol hexakisphosphate peniophora lycii 2200.0 2200.0 1 PMID:12659840 -3.1.3.26 myo-inositol hexakisphosphate rhizopus microsporus var. oligosporus 51.0 51.0 1 PMID:15163521 -3.1.3.26 myo-inositol hexakisphosphate secale cereale 655.0 506.5 2 PMID:17805950 -3.1.3.26 myo-inositol hexakisphosphate shigella sp. cd2 2230.0 1475.0 2 PMID:26808559 -3.1.3.26 myo-inositol hexakisphosphate yersinia pestis 2283.0 2283.0 1 PMID:18548246 -3.1.3.26 myo-inositol hexakisphosphate yersinia rohdei 2531.0 2531.0 1 PMID:18548246 -3.1.3.26 myo-inositol-1,2,3,4,5,6-hexakisphosphate oryza sativa japonica group 231.0 231.0 1 PMID:21220762 -3.1.3.26 o-phospho-l-ser avena sativa 5.0 5.0 1 * -3.1.3.26 p-nitrophenyl phosphate avena sativa 375.0 375.0 1 * -3.1.3.26 p-nitrophenyl phosphate escherichia coli 490.0 490.0 1 PMID:8387749 -3.1.3.26 phytate bacillus amyloliquefaciens 59600.0 59575.0 2 PMID:11583167 -3.1.3.26 phytate escherichia coli 6516.7 6516.7 1 PMID:33789740 -3.1.3.26 pyridoxal phosphate avena sativa 17.0 17.0 1 * -3.1.3.27 1,2-dioleoyl-sn-glycero-3-phosphate escherichia coli 24.0 24.0 1 PMID:24821770 -3.1.3.3 l-phosphoserine porphyromonas gingivalis 2.94 2.224 2 PMID:16832066 -3.1.3.3 l-phosphoserine pseudomonas aeruginosa 804.0 804.0 1 PMID:14699121 -3.1.3.3 l-phosphothreonine porphyromonas gingivalis 0.0004 0.0004 1 PMID:16832066 -3.1.3.3 l-phosphotyrosine porphyromonas gingivalis 3e-05 3e-05 1 PMID:16832066 -3.1.3.3 o-phospho-l-serine entamoeba histolytica 4.0 4.0 1 PMID:30935984 -3.1.3.3 o-phospho-l-serine mycobacterium marinum 11.7 11.7 1 PMID:32782143 -3.1.3.3 o-phospho-l-serine mycobacterium tuberculosis 18.6 9.375 2 PMID:25037224;PMID:29140686 -3.1.3.3 o-phospho-l-serine thermococcus onnurineus 0.182 0.168 5 PMID:23239422 -3.1.3.3 o-phospho-l-serine thermus thermophilus 1506.0 1506.0 1 PMID:30430741 -3.1.3.32 2',3'-camp acetivibrio thermocellus 8.93 5.45 2 PMID:17986465 -3.1.3.32 3'-phospho-5'-hydroxy-dna homo sapiens 0.42 0.42 1 PMID:22992732 -3.1.3.32 3'-tmp rhodothermus phage rm378 0.16 0.16 1 PMID:15579472 -3.1.3.32 bis-p-nitrophenyl phosphate acetivibrio thermocellus 23.17 16.9 3 PMID:16675457 -3.1.3.32 camp rhodothermus phage rm378 0.017 0.017 1 PMID:15579472 -3.1.3.32 dtmp kostyavirus cjw1 6.08 3.33 2 PMID:15056675 -3.1.3.32 dtmp omegavirus omega 6.08 3.355 2 PMID:15056675 -3.1.3.32 p-nitrophenyl phenylphosphonate acetivibrio thermocellus 27.83 27.83 1 PMID:17986465 -3.1.3.32 p-nitrophenyl phosphate acetivibrio thermocellus 30.83 22.915 2 PMID:16675457 -3.1.3.32 phosphorylated dna ends kostyavirus cjw1 0.0043 0.0043 1 PMID:15056675 -3.1.3.32 phosphorylated dna ends omegavirus omega 0.003 0.003 1 PMID:15056675 -3.1.3.36 1-phosphatidyl-1d-myo-inositol 3,4,5-triphosphate trypanosoma brucei 57.5 57.5 1 PMID:30420346 -3.1.3.36 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate trypanosoma brucei 140.5 140.5 1 PMID:30420346 -3.1.3.36 7-methyl-6-thioguanosine schizosaccharomyces pombe 11.0 11.0 1 PMID:15316017 -3.1.3.37 fructose 1,6-diphosphate spinacia oleracea 21.0 10.71 2 PMID:2844169 -3.1.3.37 sedoheptulose 1,7-bisphosphate synechocystis sp. 4.2 4.2 1 PMID:24286336 -3.1.3.37 sedoheptulose 1,7-diphosphate spinacia oleracea 81.0 40.92 2 PMID:2844169 -3.1.3.4 phosphatidate saccharomyces cerevisiae 7.22 3.25 3 PMID:34576941 -3.1.3.41 4-nitrophenyl phosphate aspergillus niger 108.0 108.0 1 PMID:1654806 -3.1.3.45 2-oxo-3-deoxy-d-manno-octulosonate 8-phosphate bacteroides thetaiotaomicron 1.5 1.5 1 PMID:23848398 -3.1.3.45 2-oxo-3-deoxy-d-manno-octulosonate 8-phosphate haemophilus influenzae 0.78 0.78 1 PMID:23848398 -3.1.3.45 kdn 9-phosphate bacteroides thetaiotaomicron 0.061 0.061 1 PMID:23848398 -3.1.3.45 kdn 9-phosphate haemophilus influenzae 0.021 0.021 1 PMID:23848398 -3.1.3.46 fructose 2,6-bisphosphate rattus norvegicus 0.1 0.1 1 PMID:7549867 -3.1.3.48 1-naphthyl phosphate rattus norvegicus 5.32 2.83 2 PMID:7744751 -3.1.3.48 3-o-methylfluorescein phosphate plasmodium falciparum 0.24 0.24 1 PMID:18096253 -3.1.3.48 4,6,8-trimethyl-2-oxo-2h-chromen-7-yl dihydrogen phosphate homo sapiens 71.6 16.8 3 PMID:15707933 -3.1.3.48 4,6,8-trimethyl-2-oxo-2h-chromen-7-yl dihydrogen phosphate yersinia sp. (in: enterobacteria) 36.7 36.7 1 PMID:15707933 -3.1.3.48 4-methylumbelliferyl phosphate rattus norvegicus 79.9 45.0 2 PMID:7744751 -3.1.3.48 4-nitrophenyl phosphate bacillus subtilis 0.022 0.022 1 PMID:15866923 -3.1.3.48 4-nitrophenyl phosphate drosophila melanogaster 0.997 0.997 1 PMID:33372666 -3.1.3.48 4-nitrophenyl phosphate homo sapiens 27.5 5.1 7 PMID:14734566;PMID:15707933;PMID:18358001;PMID:19053285;PMID:20236928;PMID:27208174 -3.1.3.48 4-nitrophenyl phosphate rattus norvegicus 75.3 11.6 3 PMID:1918076;PMID:7744751 -3.1.3.48 4-nitrophenyl phosphate shewanella sp. 184.9 184.9 1 PMID:18647345 -3.1.3.48 4-nitrophenyl phosphate thermus thermophilus 4013.0 2341.95 2 PMID:19657570 -3.1.3.48 4-nitrophenyl phosphate trypanosoma cruzi 2.8 2.8 1 PMID:21514274 -3.1.3.48 4-nitrophenyl phosphate yersinia enterocolitica 1440.0 1440.0 1 PMID:1429715 -3.1.3.48 6,8-difluoro-4-methylumbelliferyl phosphate homo sapiens 8.66 0.21 7 PMID:16806267;PMID:24793162 -3.1.3.48 6,8-difluoro-4-methylumbelliferyl phosphate thermococcus kodakarensis 30.0 17.37 2 PMID:29791483 -3.1.3.48 [eps15 peptide846-854 p850v]-tyrosine phosphate homo sapiens 13.4 13.4 1 PMID:25728925 -3.1.3.48 [eps15 peptide846-854]-tyrosine phosphate homo sapiens 17.3 17.3 1 PMID:25728925 -3.1.3.48 aaaaapyrhrr homo sapiens 30.0 30.0 1 PMID:21291263 -3.1.3.48 adedfpyaa homo sapiens 8.0 8.0 1 PMID:21291263 -3.1.3.48 akfedtpyaa homo sapiens 19.0 19.0 1 PMID:21291263 -3.1.3.48 arkripyaa homo sapiens 39.0 39.0 1 PMID:21291263 -3.1.3.48 avwefpypyaa homo sapiens 24.0 24.0 1 PMID:21291263 -3.1.3.48 awspyadpyaa homo sapiens 13.0 13.0 1 PMID:21291263 -3.1.3.48 aytepytpyaa homo sapiens 17.0 17.0 1 PMID:21291263 -3.1.3.48 bis(4-nitrophenyl) phosphate homo sapiens 0.033 0.033 1 PMID:27208174 -3.1.3.48 daedfpyaa homo sapiens 30.0 30.0 1 PMID:21291263 -3.1.3.48 ddt-(3,5-difluoro)ydpyaa homo sapiens 6.0 6.0 1 PMID:18798640 -3.1.3.48 ddtydpyaa homo sapiens 33.0 33.0 1 PMID:18798640 -3.1.3.48 dfedfpyaa homo sapiens 37.0 37.0 1 PMID:21291263 -3.1.3.48 dnl-(3,5-difluoro)ypywd homo sapiens 6.0 6.0 1 PMID:18798640 -3.1.3.48 dnlypywd homo sapiens 32.0 32.0 1 PMID:18798640 -3.1.3.48 drvpyihpfhl rattus norvegicus 3.1 3.1 1 PMID:1918076 -3.1.3.48 dwedfpyaa homo sapiens 30.0 30.0 1 PMID:21291263 -3.1.3.48 eadtapyaa homo sapiens 26.0 26.0 1 PMID:21291263 -3.1.3.48 eifdfpyaa homo sapiens 32.0 29.0 2 PMID:21291263 -3.1.3.48 fdedfpyaa homo sapiens 30.0 30.0 1 PMID:21291263 -3.1.3.48 fdidipyaa homo sapiens 33.0 31.5 2 PMID:21291263 -3.1.3.48 fydidpyaa homo sapiens 66.0 58.0 2 PMID:21291263 -3.1.3.48 gesdggpymdmskd homo sapiens 200.0 200.0 1 * -3.1.3.48 gngdpympmspks homo sapiens 18.4 13.049999999999999 2 PMID:17135270 -3.1.3.48 inositol hexakisphosphate bdellovibrio bacteriovorus 124.0 124.0 1 PMID:24718691 -3.1.3.48 insulin receptor phosphopeptide homo sapiens 61.5 61.5 1 PMID:15707933 -3.1.3.48 krliedne(py)targq bacillus subtilis 0.016 0.016 1 PMID:15866923 -3.1.3.48 liednepytarqga homo sapiens 8.3 8.3 1 PMID:21291263 -3.1.3.48 lysozyme homo sapiens 0.35 0.14 3 * -3.1.3.48 p-nitrophenyl phosphate homo sapiens 3.1 2.9 3 PMID:17135270;PMID:18056643 -3.1.3.48 pgsaap-py-lktkfi homo sapiens 3.6 3.6 1 PMID:30289412 -3.1.3.48 phenyl phosphate rattus norvegicus 64.9 38.35 2 PMID:7744751 -3.1.3.48 phosphotyrosine rattus norvegicus 72.9 43.0 2 PMID:7744751 -3.1.3.48 platelet-derived growth factor receptor homo sapiens 7.2 7.2 1 PMID:8119896 -3.1.3.48 pqdkey-py-kvkepg homo sapiens 3.1 3.1 1 PMID:30289412 -3.1.3.48 re-(3,5-difluoro)yefpyaa homo sapiens 44.0 44.0 1 PMID:18798640 -3.1.3.48 reyefpyaa homo sapiens 33.0 33.0 1 PMID:18798640 -3.1.3.48 rkgsgd-py-mpmspk homo sapiens 3.2 3.2 1 PMID:30289412 -3.1.3.48 rristpyaa homo sapiens 49.0 49.0 1 PMID:21291263 -3.1.3.48 sasaspydwef homo sapiens 35.0 23.5 2 PMID:21291263 -3.1.3.48 sasaspysasa homo sapiens 42.0 26.0 3 PMID:21291263 -3.1.3.48 tatepqpyqpgen homo sapiens 9.7 9.7 1 PMID:21291263 -3.1.3.48 tgfltelpyvatrwy homo sapiens 177.0 177.0 1 * -3.1.3.48 tstepqpyqpgenl homo sapiens 258.0 133.45 2 PMID:21291263 -3.1.3.48 wagddpyaa homo sapiens 57.0 31.5 2 PMID:21291263 -3.1.3.48 wdedfpyaa homo sapiens 48.0 48.0 1 PMID:21291263 -3.1.3.48 wdedfpydwef homo sapiens 75.0 59.0 2 PMID:21291263 -3.1.3.48 wdedfpyrwkf homo sapiens 73.0 57.5 2 PMID:21291263 -3.1.3.48 wdedfpysasa homo sapiens 50.0 43.5 2 PMID:21291263 -3.1.3.48 wrkrfpydwef homo sapiens 1.7 1.5 2 PMID:21291263 -3.1.3.5 (polyphosphate)n escherichia coli 0.05 0.05 1 PMID:15489502 -3.1.3.5 3'-amp escherichia coli 9.84 9.84 1 PMID:15489502 -3.1.3.5 3'-cmp escherichia coli 5.93 5.93 1 PMID:15489502 -3.1.3.5 4-nitrophenyl phosphate bacillus subtilis 61.0 61.0 1 PMID:27907199 -3.1.3.5 4-nitrophenyl phosphate escherichia coli 129.0 40.8 3 PMID:15489502;PMID:23333297 -3.1.3.5 5'-amp escherichia coli 750.0 459.1 3 PMID:15489502;PMID:15709736;PMID:23333297 -3.1.3.5 5'-amp homo sapiens 187.0 187.0 1 PMID:22997138 -3.1.3.5 5'-amp ophiocordyceps sinensis 4.521 4.521 1 PMID:31899296 -3.1.3.5 5'-cmp homo sapiens 202.0 202.0 1 PMID:22997138 -3.1.3.5 5'-damp escherichia coli 0.3 0.3 1 PMID:15489502 -3.1.3.5 5'-damp homo sapiens 174.0 174.0 1 PMID:22997138 -3.1.3.5 5'-dcmp escherichia coli 0.23 0.23 1 PMID:15489502 -3.1.3.5 5'-dgmp escherichia coli 8.04 4.119999999999999 2 PMID:15489502 -3.1.3.5 5'-dgmp legionella pneumophila 20.7 20.7 1 PMID:24456211 -3.1.3.5 5'-dimp escherichia coli 0.24 0.24 1 PMID:15489502 -3.1.3.5 5'-dtmp escherichia coli 0.16 0.16 1 PMID:15489502 -3.1.3.5 5'-dump escherichia coli 0.23 0.23 1 PMID:15489502 -3.1.3.5 5'-gmp bacillus subtilis 0.06 0.06 1 PMID:27907199 -3.1.3.5 5'-gmp escherichia coli 11.0 11.0 1 PMID:15489502 -3.1.3.5 5'-gmp homo sapiens 132.0 132.0 1 PMID:22997138 -3.1.3.5 5'-gmp legionella pneumophila 12.4 12.4 1 PMID:24456211 -3.1.3.5 5'-imp homo sapiens 104.0 104.0 1 PMID:22997138 -3.1.3.5 5'-imp legionella pneumophila 0.3 0.3 1 PMID:24456211 -3.1.3.5 5'-tmp homo sapiens 40.0 40.0 1 PMID:22997138 -3.1.3.5 5'-ump homo sapiens 289.0 289.0 1 PMID:22997138 -3.1.3.5 5'-ump mus musculus 1.2 1.2 1 PMID:22925580 -3.1.3.5 5'-xmp bacillus subtilis 0.31 0.31 1 PMID:27907199 -3.1.3.5 5-phosphoribosyl-1-diphosphate bacillus subtilis 0.17 0.17 1 PMID:27907199 -3.1.3.5 adp escherichia coli 613.2 329.40000000000003 2 PMID:23333297 -3.1.3.5 atp escherichia coli 757.0 396.75 2 PMID:23333297 -3.1.3.5 d-ribose 5-phosphate bacillus subtilis 1.84 1.84 1 PMID:27907199 -3.1.3.5 inosine bos taurus 40.0 40.0 1 PMID:15606776 -3.1.3.5 inosine homo sapiens 22.0 20.5 2 PMID:15917509 -3.1.3.5 p-nitrophenyl phosphate escherichia coli 60.0 30.28 2 PMID:15489502;PMID:15709736 -3.1.3.5 ribavirin homo sapiens 0.15 0.047 4 PMID:15917509 -3.1.3.50 d-sorbitol 6-phosphate escherichia coli 63.0 42.0 2 PMID:29743459 -3.1.3.52 4-nitrophenyl phosphate homo sapiens 40.9 20.95 2 PMID:30451284 -3.1.3.56 1,5-bisdiphosphoinositol 2,3,4,6-tetrakisphosphate saccharomyces cerevisiae 0.63 0.63 1 PMID:29540476 -3.1.3.56 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate saccharomyces cerevisiae 1.32 1.315 2 PMID:29540476 -3.1.3.56 5-diphosphoinositol 1,3,4,6-tetrakisphosphate saccharomyces cerevisiae 0.77 0.77 1 PMID:29540476 -3.1.3.56 7-methyl-6-thioguanosine schizosaccharomyces pombe 11.0 11.0 1 PMID:15316017 -3.1.3.56 d-myo-inositol 1,4,5-trisphosphate bos taurus 340.0 340.0 1 PMID:1312931 -3.1.3.6 (polyphosphate)n escherichia coli 0.05 0.05 1 PMID:15489502 -3.1.3.6 2',3'-camp escherichia coli 190.0 131.5 2 PMID:33671286 -3.1.3.6 2',3'-ccmp escherichia coli 100.0 66.5 2 PMID:33671286 -3.1.3.6 2',3'-cgmp escherichia coli 84.0 71.0 2 PMID:33671286 -3.1.3.6 2',3'-cump escherichia coli 260.0 207.5 2 PMID:33671286 -3.1.3.6 3',5'-camp escherichia coli 4.7 2.63 2 PMID:33671286 -3.1.3.6 3'-amp escherichia coli 176.0 92.92 6 PMID:15489502;PMID:27294396;PMID:33671286 -3.1.3.6 3'-cmp escherichia coli 5.93 5.93 1 PMID:15489502 -3.1.3.6 5'-amp escherichia coli 4.9 4.9 1 PMID:15489502 -3.1.3.6 5'-dgmp escherichia coli 8.04 8.04 1 PMID:15489502 -3.1.3.6 5'-gmp escherichia coli 11.0 11.0 1 PMID:15489502 -3.1.3.6 bis-4-nitrophenylphosphate escherichia coli 340.0 252.0 2 PMID:33671286 -3.1.3.6 c-di-amp escherichia coli 0.4 0.20600000000000002 2 PMID:33671286 -3.1.3.6 c-di-gmp escherichia coli 0.07 0.03515 2 PMID:33671286 -3.1.3.6 cdp-choline escherichia coli 5.7 3.105 2 PMID:33671286 -3.1.3.6 p-nitrophenyl phosphate escherichia coli 3.55 3.55 1 PMID:15489502 -3.1.3.6 papa escherichia coli 1.3 0.6502 2 PMID:33671286 -3.1.3.67 phosphatidylinositol 3,4-bisphosphate ciona intestinalis 0.12 0.12 1 PMID:22645351 -3.1.3.7 2'-deoxyadenosine 3',5'-bisphosphate chromobacterium violaceum 7.1 7.1 1 PMID:24401123 -3.1.3.7 2'-deoxycytidine 3',5'-bisphosphate chromobacterium violaceum 9.4 9.4 1 PMID:24401123 -3.1.3.7 2'-deoxyguanosine 3',5'-bisphosphate chromobacterium violaceum 4.2 4.2 1 PMID:24401123 -3.1.3.7 2'-deoxythymidine 3',5'-bisphosphate chromobacterium violaceum 4.3 4.3 1 PMID:24401123 -3.1.3.7 2'-deoxyuridine 3',5'-bisphosphate chromobacterium violaceum 5.2 5.2 1 PMID:24401123 -3.1.3.7 3'-phosphoadenosine 5'-phosphate saccharomyces cerevisiae 11.0 11.0 1 PMID:24613729 -3.1.3.7 5'-phosphoadenylyl-(3'->5')-adenosine chromobacterium violaceum 0.05 0.05 1 PMID:24401123 -3.1.3.7 adenosine 2',5'-bisphosphate escherichia coli 13.2 13.2 1 PMID:17616624 -3.1.3.7 adenosine 3',5'-bisphosphate chromobacterium violaceum 22.0 22.0 1 PMID:24401123 -3.1.3.7 adenosine 3',5'-bisphosphate debaryomyces hansenii 2.94 2.4305 2 PMID:17983588 -3.1.3.7 adenosine 3',5'-bisphosphate escherichia coli 11.4 11.4 1 PMID:17616624 -3.1.3.7 adenosine 3',5'-bisphosphate mycobacterium tuberculosis 5.4 5.4 1 PMID:18454554 -3.1.3.7 adenosine 3',5'-bisphosphate pyrococcus yayanosii 1259.0 1259.0 1 PMID:34281213 -3.1.3.7 d-fructose 1,6-bisphosphate escherichia coli 1.1 1.1 1 PMID:17616624 -3.1.3.7 d-fructose 1,6-bisphosphate mycobacterium tuberculosis 0.24 0.24 1 PMID:18454554 -3.1.3.7 d-myo-inositol monophosphate mycobacterium tuberculosis 0.31 0.31 1 PMID:18454554 -3.1.3.7 guanosine 3',5'-bisphosphate chromobacterium violaceum 12.3 12.3 1 PMID:24401123 -3.1.3.7 n6-methyl-5'-phosphoadenylyl-(3'->5')-adenosine chromobacterium violaceum 11.6 11.6 1 PMID:24401123 -3.1.3.7 nadp+ escherichia coli 0.7 0.7 1 PMID:17616624 -3.1.3.7 nadph escherichia coli 1.45 1.45 1 PMID:17616624 -3.1.3.7 thymidine 3',5'-bisphosphate chromobacterium violaceum 3.3 3.3 1 PMID:24401123 -3.1.3.7 uridine 3',5'-bisphosphate chromobacterium violaceum 5.4 5.4 1 PMID:24401123 -3.1.3.72 myo-inositol hexakisphosphate shigella sp. cd2 2230.0 1475.0 2 PMID:26808559 -3.1.3.74 pyridoxal 5'-phosphate homo sapiens 1.52 1.52 1 PMID:14522954 -3.1.3.74 pyridoxal 5'-phosphate mus musculus 2.0 2.0 1 PMID:25783190 -3.1.3.74 pyridoxal 5'-phosphate paenibacillus thiaminolyticus 19.4 19.4 1 PMID:16336194 -3.1.3.74 pyridoxal-5'-phosphate paenibacillus thiaminolyticus 19.0 19.0 1 PMID:16336194 -3.1.3.74 pyridoxamine 5'-phosphate homo sapiens 0.45 0.45 1 PMID:14522954 -3.1.3.74 pyridoxine 5'-phosphate homo sapiens 1.25 1.25 1 PMID:14522954 -3.1.3.75 4-nitrophenyl phosphate pseudomonas aeruginosa 87.1 87.1 1 PMID:21515416 -3.1.3.75 o-phosphoethanolamine homo sapiens 2.27 2.27 1 PMID:15175005 -3.1.3.75 p-nitrophenyl phosphate pseudomonas aeruginosa 7900000.0 3550000.0 4 PMID:18801468;PMID:20064618 -3.1.3.75 phosphocholine arabidopsis thaliana 1.04 1.04 1 PMID:22024570 -3.1.3.75 phosphocholine homo sapiens 1.98 1.98 1 PMID:15175005 -3.1.3.75 phosphoethanolamine arabidopsis thaliana 13.0 13.0 1 PMID:22024570 -3.1.3.76 4-nitrophenyl phosphate homo sapiens 0.013 0.00955 2 PMID:12574508 -3.1.3.76 4-nitrophenyl phosphate rattus norvegicus 1.61 1.225 2 PMID:12574508 -3.1.3.76 farnesyl diphosphate homo sapiens 0.25 0.25 1 PMID:16414022 -3.1.3.76 farnesyl phosphate homo sapiens 0.71 0.71 1 PMID:16414022 -3.1.3.76 geranyl phosphate homo sapiens 0.51 0.51 1 PMID:16414022 -3.1.3.76 geranylgeranyl diphosphate homo sapiens 0.13 0.13 1 PMID:16414022 -3.1.3.76 geranylgeranyl phosphate homo sapiens 1.85 1.85 1 PMID:16414022 -3.1.3.8 1-l-myo-inositol 1,2,3,4,5-pentakisphosphate pantoea agglomerans 16.0 16.0 1 PMID:15648979 -3.1.3.8 1-l-myo-inositol 1,2,3,5,6-pentakisphosphate pantoea agglomerans 16.0 16.0 1 PMID:15648979 -3.1.3.8 1-naphthyl phosphate raoultella terrigena 2.0 2.0 1 PMID:9169005 -3.1.3.8 2-naphthyl phosphate raoultella terrigena 6.0 6.0 1 PMID:9169005 -3.1.3.8 4-methylumbelliferyl phosphate yersinia mollaretii 5.33 5.33 1 PMID:30141080 -3.1.3.8 4-nitrophenyl phosphate aspergillus ficuum 104.0 104.0 1 PMID:3035533 -3.1.3.8 4-nitrophenyl phosphate aspergillus fumigatus 358000.0 357500.0 3 PMID:10679211 -3.1.3.8 4-nitrophenyl phosphate penicillium parvum 11.8 11.8 1 PMID:19818856 -3.1.3.8 4-nitrophenyl phosphate raoultella terrigena 20.0 20.0 1 PMID:9169005 -3.1.3.8 4-nitrophenylphosphate arabidopsis thaliana 161.9 161.9 1 PMID:19633233 -3.1.3.8 adp raoultella terrigena 9.0 9.0 1 PMID:9169005 -3.1.3.8 amp raoultella terrigena 8.0 8.0 1 PMID:9169005 -3.1.3.8 atp raoultella terrigena 6.0 6.0 1 PMID:9169005 -3.1.3.8 d-fructose 1,6-diphosphate pantoea agglomerans 1.1 1.1 1 PMID:15648979 -3.1.3.8 d-fructose 1-phosphate pantoea agglomerans 1.6 1.6 1 PMID:15648979 -3.1.3.8 d-glucose 1-phosphate pantoea agglomerans 101.0 101.0 2 PMID:15648978;PMID:15648979 -3.1.3.8 d-glucose 6-phosphate pantoea agglomerans 2.9 2.9 1 PMID:15648979 -3.1.3.8 d-ribose 5-phosphate pantoea agglomerans 1.1 1.1 1 PMID:15648979 -3.1.3.8 diphosphate raoultella terrigena 11.0 11.0 1 PMID:9169005 -3.1.3.8 fructose 1,6-diphosphate raoultella terrigena 10.0 10.0 1 PMID:9169005 -3.1.3.8 fructose 6-phosphate raoultella terrigena 6.0 6.0 1 PMID:9169005 -3.1.3.8 glucose 6-phosphate raoultella terrigena 2.0 2.0 1 PMID:9169005 -3.1.3.8 glycerol 2-phosphate raoultella terrigena 4.0 4.0 1 PMID:9169005 -3.1.3.8 myo-inositol hexakisphosphate arabidopsis thaliana 8.85 8.85 1 PMID:19633233 -3.1.3.8 myo-inositol hexakisphosphate aspergillus ficuum 360.0 348.0 7 PMID:10527865;PMID:10964658;PMID:11812011;PMID:12659840;PMID:3035533 -3.1.3.8 myo-inositol hexakisphosphate aspergillus fumigatus 412000.0 114.0 5 PMID:10679211;PMID:10964658;PMID:17534560 -3.1.3.8 myo-inositol hexakisphosphate aspergillus niger 300000.0 374.0 4 PMID:15776271;PMID:17958557;PMID:19530713;PMID:20376636 -3.1.3.8 myo-inositol hexakisphosphate bacillus sp. (in: firmicutes) 26.6 21.575000000000003 2 PMID:11594462;PMID:22775008 -3.1.3.8 myo-inositol hexakisphosphate bacillus subtilis 4965.7 1837.8 3 * -3.1.3.8 myo-inositol hexakisphosphate burkholderia sp. a13(2014) 236.2 236.2 1 PMID:25833676 -3.1.3.8 myo-inositol hexakisphosphate debaryomyces castellii 59.2 51.2 3 PMID:18046551;PMID:18242101 -3.1.3.8 myo-inositol hexakisphosphate dendroctonus frontalis 375200.0 329900.0 2 PMID:26536874 -3.1.3.8 myo-inositol hexakisphosphate enterobacter sp. acss 1640.0 1640.0 1 PMID:27250653 -3.1.3.8 myo-inositol hexakisphosphate escherichia coli 3397.0 2118.5 2 PMID:19530713;PMID:23794051 -3.1.3.8 myo-inositol hexakisphosphate kodamaea ohmeri 0.93 0.93 1 PMID:18040741 -3.1.3.8 myo-inositol hexakisphosphate nicotiana tabacum 2056.0 1482.0 2 PMID:17897689 -3.1.3.8 myo-inositol hexakisphosphate pantoea agglomerans 21.0 21.0 2 PMID:15648978;PMID:15648979 -3.1.3.8 myo-inositol hexakisphosphate pectobacterium carotovorum 950.0 950.0 1 PMID:19884763 -3.1.3.8 myo-inositol hexakisphosphate penicillium parvum 134.0 117.0 3 PMID:19818856 -3.1.3.8 myo-inositol hexakisphosphate pseudomonas sp. 20.39 11.030000000000001 2 PMID:30037556 -3.1.3.8 myo-inositol hexakisphosphate raoultella terrigena 180.0 180.0 1 PMID:9169005 -3.1.3.8 myo-inositol hexakisphosphate rhizopus microsporus var. oligosporus 51.0 51.0 1 PMID:15163521 -3.1.3.8 myo-inositol hexakisphosphate shigella sp. cd2 2230.0 1475.0 2 PMID:26808559 -3.1.3.8 myo-inositol hexakisphosphate streptomyces sp. 3.0 3.0 1 PMID:27132983 -3.1.3.8 myo-inositol hexakisphosphate thermothelomyces heterothallicus 1300.0 1300.0 1 PMID:26758064 -3.1.3.8 myo-inositol hexakisphosphate thermothelomyces thermophilus 5100.0 2568.9 2 PMID:15063805;PMID:26433599 -3.1.3.8 myo-inositol hexakisphosphate yersinia pestis 2283.0 2283.0 1 PMID:18548246 -3.1.3.8 myo-inositol hexakisphosphate yersinia rohdei 2531.0 2531.0 1 PMID:18548246 -3.1.3.8 myo-inositol hexakisphosphate disodium salt aspergillus japonicus 231.0 231.0 1 PMID:19025560 -3.1.3.8 myo-inositol hexakisphosphate disodium salt aspergillus niger 281.0 281.0 1 PMID:19025560 -3.1.3.8 myo-inositol hexakisphosphate sodium salt aspergillus japonicus 279.0 279.0 1 PMID:19025560 -3.1.3.8 myo-inositol hexakisphosphate sodium salt aspergillus niger 253.0 253.0 1 PMID:19025560 -3.1.3.8 myo-inositol-1,2,3,4,5,6-hexakisphosphate aspergillus niger 350.0 255.5 2 PMID:20376636 -3.1.3.8 myo-inositol-1,2,3,4,5,6-hexakisphosphate bacillus sp. (in: firmicutes) 94.4 20.0 6 PMID:21707924 -3.1.3.8 myo-inositol-1,2,3,4,5,6-hexakisphosphate hordeum vulgare 260.0 256.5 2 PMID:21220762 -3.1.3.8 myo-inositol-1,2,3,4,5,6-hexakisphosphate klebsiella sp. 370.0 370.0 1 PMID:20392204 -3.1.3.8 myo-inositol-1,2,3,4,5,6-hexakisphosphate triticum aestivum 279.0 274.5 2 PMID:21220762 -3.1.3.8 myo-inositol-1,2,3,4,5,6-hexakisphosphate zea mays 248.0 248.0 1 PMID:21220762 -3.1.3.8 nadp+ raoultella terrigena 46.0 46.0 1 PMID:9169005 -3.1.3.8 p-nitrophenyl phosphate aspergillus niger 1.9 1.9 1 PMID:17958557 -3.1.3.8 p-nitrophenyl phosphate debaryomyces castellii 44.2 44.2 1 PMID:18046551 -3.1.3.8 p-nitrophenyl phosphate pantoea agglomerans 8.2 8.2 1 PMID:15648978 -3.1.3.8 phosphoenolpyruvate arabidopsis thaliana 198.0 198.0 1 PMID:19633233 -3.1.3.8 phytate aspergillus neoniger 634.94 634.94 1 PMID:30910675 -3.1.3.8 phytate aspergillus niger 1260.0 1260.0 1 PMID:21294512 -3.1.3.8 phytate bacillus amyloliquefaciens 59600.0 59575.0 2 PMID:11583167 -3.1.3.8 phytate bacillus licheniformis 27.63 27.63 1 PMID:33220867 -3.1.3.8 phytate bacillus sp. sj-10 60.407 42.83 2 PMID:31000166 -3.1.3.8 phytate bacillus sp. sj-48 2.64 2.08 2 PMID:31000166 -3.1.3.8 phytate cronobacter turicensis 2778.0 2778.0 1 PMID:36195031 -3.1.3.8 phytate escherichia coli 4470.0 4470.0 1 PMID:21294512 -3.1.3.8 phytate lactiplantibacillus plantarum 11619.7 6166.25 2 PMID:35168166 -3.1.3.8 phytate orbilia oligospora 13.57 13.57 1 PMID:32252770 -3.1.3.8 phytate pseudomonas sp. fb15 60.407 31.5235 2 PMID:31000166 -3.1.3.8 phytate serratia sp. (in: enterobacteria) 112.7 68.08 2 PMID:21853317 -3.1.3.82 d-fructose 1,6-bisphosphate bordetella bronchiseptica 0.55 0.55 1 PMID:20050614 -3.1.3.82 d-fructose 1,6-bisphosphate escherichia coli 0.039 0.039 1 PMID:20050615 -3.1.3.82 d-glycero-alpha-d-manno-heptose 1,7-bisphosphate bordetella bronchiseptica 5.9 5.9 1 PMID:20050615 -3.1.3.82 d-glycero-alpha-d-manno-heptose 1,7-bisphosphate escherichia coli 4.6 4.6 2 PMID:20050614;PMID:20050615 -3.1.3.82 d-glycero-alpha-d-manno-heptose 1,7-bisphosphate mesorhizobium loti 4.4 4.4 1 PMID:20050615 -3.1.3.82 d-glycero-beta-d-manno-heptose 1,7-bisphosphate bordetella bronchiseptica 22.0 22.0 1 PMID:20050615 -3.1.3.82 d-glycero-beta-d-manno-heptose 1,7-bisphosphate escherichia coli 35.7 35.7 3 PMID:20050614;PMID:20050615;PMID:20050699 -3.1.3.82 d-glycero-beta-d-manno-heptose 1,7-bisphosphate mesorhizobium loti 18.0 18.0 1 PMID:20050615 -3.1.3.82 d-sedoheptulose 1,7-bisphosphate escherichia coli 0.51 0.51 1 PMID:20050615 -3.1.3.83 d-glycero-alpha-d-manno-heptose 1,7-bisphosphate bacteroides thetaiotaomicron 29.0 29.0 1 PMID:20050615 -3.1.3.83 d-glycero-beta-d-manno-heptose 1,7-bisphosphate bacteroides thetaiotaomicron 13.0 13.0 1 PMID:20050615 -3.1.3.84 adp-ribose 1''-phosphate saccharomyces cerevisiae 0.028 0.028 1 PMID:15684411 -3.1.3.84 adp-ribose 1''-phosphate severe acute respiratory syndrome-related coronavirus 0.0865 0.0865 1 PMID:16271890 -3.1.3.86 1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate homo sapiens 1.44 1.065 2 PMID:28792888;PMID:34314064 -3.1.3.86 1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate trypanosoma brucei 57.5 57.5 1 PMID:30420346 -3.1.3.86 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate trypanosoma brucei 140.5 140.5 1 PMID:30420346 -3.1.3.86 1d-myo-inositol 1,3,4,5-tetrakisphosphate homo sapiens 4.85 4.85 1 PMID:34314064 -3.1.3.86 inositol 1,3,4,5-tetrakisphosphate homo sapiens 1.32 1.32 1 PMID:28792888 -3.1.3.89 4-nitrophenyl phosphate escherichia coli 0.56 0.56 1 PMID:15489502 -3.1.3.89 4-nitrophenyl phosphate saccharomyces cerevisiae 3.48 3.48 1 PMID:29752939 -3.1.3.89 5'-damp escherichia coli 0.3 0.22 2 PMID:15489502;PMID:18353368 -3.1.3.89 5'-damp saccharomyces cerevisiae 1.0 1.0 1 PMID:29752939 -3.1.3.89 5'-dcmp escherichia coli 0.23 0.23 1 PMID:15489502 -3.1.3.89 5'-dcmp saccharomyces cerevisiae 0.28 0.28 1 PMID:29752939 -3.1.3.89 5'-dgmp escherichia coli 0.2 0.2 1 PMID:15489502 -3.1.3.89 5'-dgmp saccharomyces cerevisiae 1.2 1.2 1 PMID:29752939 -3.1.3.89 5'-dimp escherichia coli 0.24 0.24 1 PMID:15489502 -3.1.3.89 5'-dtmp escherichia coli 0.16 0.16 1 PMID:15489502 -3.1.3.89 5'-dtmp saccharomyces cerevisiae 1.1 1.1 1 PMID:29752939 -3.1.3.89 5'-dump escherichia coli 0.23 0.23 1 PMID:15489502 -3.1.3.9 d-glucose 6-phosphate mus musculus 41.0 40.0 3 PMID:34952005 -3.1.3.9 glucose 6-phosphate rattus norvegicus 700.0 700.0 1 PMID:2830258 -3.1.3.90 maltose 6'-phosphate enterococcus faecalis 128.0 128.0 1 PMID:23490043 -3.1.3.91 n7-methyl-gmp drosophila melanogaster 6.3 6.3 1 PMID:23223233 -3.1.3.91 n7-methyl-gmp homo sapiens 0.24 0.24 1 PMID:23223233 -3.1.3.92 kanosamine 6-phosphate bacillus cereus 0.11 0.11 1 PMID:31622586 -3.1.3.92 kanosamine 6-phosphate bacillus subtilis 32.0 32.0 1 PMID:23586652 -3.1.3.96 pseudouridine 5'-phosphate homo sapiens 1.6 1.6 1 PMID:20722631 -3.1.3.97 2'-deoxy-adenosine 3',5'-bisphosphate chromobacterium violaceum 7.1 7.1 1 PMID:24401123 -3.1.3.97 2'-deoxy-cytosine 3',5'-bisphosphate chromobacterium violaceum 9.4 9.4 1 PMID:24401123 -3.1.3.97 2'-deoxy-guanosine 3',5'-bisphosphate chromobacterium violaceum 4.2 4.2 1 PMID:24401123 -3.1.3.97 2'-deoxy-inosine 3',5'-bisphosphate chromobacterium violaceum 4.3 4.3 1 PMID:24401123 -3.1.3.97 2'-deoxy-uridine 3',5'-bisphosphate chromobacterium violaceum 5.2 5.2 1 PMID:24401123 -3.1.3.97 5'-phosphoadenylyl-(3',5')-adenosine chromobacterium violaceum 0.05 0.05 1 PMID:24401123 -3.1.3.97 adenosine 3',5'-bisphosphate chromobacterium violaceum 22.0 22.0 1 PMID:24401123 -3.1.3.97 cytosine 3',5'-bisphosphate chromobacterium violaceum 8.6 8.6 1 PMID:24401123 -3.1.3.97 guanosine 3',5'-bisphosphate chromobacterium violaceum 12.3 12.3 1 PMID:24401123 -3.1.3.97 inosine 3',5'-bisphosphate chromobacterium violaceum 3.3 3.3 1 PMID:24401123 -3.1.3.97 n6-methyl adenosine 3',5'-bisphosphate chromobacterium violaceum 11.6 11.6 1 PMID:24401123 -3.1.3.97 uridine 3',5'-bisphosphate chromobacterium violaceum 5.4 5.4 1 PMID:24401123 -3.1.3.99 4-nitrophenyl phosphate plasmodium falciparum 0.0026 0.0026 1 PMID:32591529 -3.1.3.99 amp plasmodium falciparum 23.2 17.85 2 PMID:32591529 -3.1.3.99 imp plasmodium falciparum 13.5 11.9 2 PMID:32591529 -3.1.30.2 b-form dna serratia marcescens 737.6 737.6 1 * -3.1.30.2 b-z-hybrid form dna serratia marcescens 1.2 0.82 2 * -3.1.4.1 (5'-gatctaaaagactt-3')-phosphotyrosine saccharomyces cerevisiae 0.28 0.28 1 PMID:25609251 -3.1.4.1 2',3'-camp acetivibrio thermocellus 23.2 12.45 2 PMID:17986465 -3.1.4.1 bis(4-nitrophenyl)phosphate arabidopsis thaliana 7.4 7.4 1 PMID:18052196 -3.1.4.1 bis-p-nitrophenyl phosphate escherichia coli 20.3 20.05 2 PMID:17586769 -3.1.4.1 bis-p-nitrophenyl phosphate methanocaldococcus jannaschii 130.2 125.9 3 PMID:15128743 -3.1.4.1 p-nitrophenyl 5'-thymidine monophosphate methanocaldococcus jannaschii 3.26 3.26 1 PMID:15128743 -3.1.4.1 p-nitrophenyl ethyl phosphate rhizobium leguminosarum 9.5 9.5 1 PMID:18793651 -3.1.4.1 p-nitrophenyl phenylphosphonate rhizobium leguminosarum 16.0 16.0 1 PMID:18793651 -3.1.4.1 p-nitrophenylphosphorylcholine methanocaldococcus jannaschii 52.9 30.75 2 PMID:15128743 -3.1.4.12 2-hexadecanoylamino-4-nitrophenylphosphocholine bacillus cereus 5.9 5.9 1 PMID:12761162 -3.1.4.12 adp homo sapiens 0.374 0.374 1 PMID:26783088 -3.1.4.12 adp-ribose homo sapiens 2.07 2.07 1 PMID:26783088 -3.1.4.12 atp homo sapiens 0.7357 0.7357 1 PMID:26783088 -3.1.4.12 cdp-choline homo sapiens 1.29 1.29 1 PMID:26783088 -3.1.4.12 cdp-ethanolamine homo sapiens 1.864 1.864 1 PMID:26783088 -3.1.4.12 lysophosphatidylcholine bacillus cereus 13.0 13.0 1 PMID:12761162 -3.1.4.12 sphingomyelin bacillus cereus 400.0 210.0 3 PMID:11060353;PMID:12761162;PMID:12843611 -3.1.4.14 2',3'-camp pseudomonas aeruginosa 0.004 0.004 1 PMID:20064615 -3.1.4.14 bis-4-nitrophenyl phosphate pseudomonas aeruginosa 0.21 0.21 1 PMID:20064615 -3.1.4.16 2',3'-camp escherichia coli 190.0 95.0 8 PMID:15210699;PMID:33671286;PMID:33923386 -3.1.4.16 2',3'-ccmp escherichia coli 100.0 100.0 5 PMID:33671286 -3.1.4.16 2',3'-cgmp escherichia coli 84.0 71.0 6 PMID:15210699;PMID:33671286 -3.1.4.16 2',3'-cgmp staphylococcus aureus 12016.7 12016.7 1 PMID:31422053 -3.1.4.16 2',3'-cump escherichia coli 260.0 260.0 5 PMID:33671286 -3.1.4.16 2'-amp escherichia coli 3.09 3.09 1 PMID:15210699 -3.1.4.16 3',5'-camp escherichia coli 4.7 0.56 5 PMID:33671286 -3.1.4.16 3',5'-cyclic diadenosine monophosphate escherichia coli 0.4 0.4 3 PMID:33671286 -3.1.4.16 3',5'-cyclic diguanosine monophosphate escherichia coli 0.07 0.07 3 PMID:33671286 -3.1.4.16 3'-amp escherichia coli 176.0 176.0 3 PMID:33671286 -3.1.4.16 5'-phosphoadenylyl-3',5'-adenosine escherichia coli 1.3 0.6502 2 PMID:33671286 -3.1.4.16 5'-phosphoadenylyl-3'->5'-adenosine escherichia coli 1.3 1.3 1 PMID:33671286 -3.1.4.16 adp escherichia coli 1.24 1.24 1 PMID:15210699 -3.1.4.16 atp escherichia coli 3.78 3.78 1 PMID:15210699 -3.1.4.16 bis-4-nitrophenyl phosphate escherichia coli 340.0 252.0 2 PMID:33671286 -3.1.4.16 bis-4-nitrophenylphosphate escherichia coli 340.0 340.0 3 PMID:33671286 -3.1.4.16 bis-p-nitrophenyl phosphate escherichia coli 72.0 72.0 1 PMID:18757371 -3.1.4.16 bis-p-nitrophenyl phosphate mycobacterium tuberculosis 12.4 12.4 1 PMID:18757371 -3.1.4.16 c-di-amp escherichia coli 0.4 0.20600000000000002 2 PMID:33671286 -3.1.4.16 c-di-gmp escherichia coli 0.07 0.03515 2 PMID:33671286 -3.1.4.16 cdp escherichia coli 4.83 4.83 1 PMID:15210699 -3.1.4.16 cdp-choline escherichia coli 5.7 0.51 5 PMID:33671286 -3.1.4.16 ctp escherichia coli 3.36 3.36 1 PMID:15210699 -3.1.4.16 cyclic 2',3'-amp escherichia coli 2.95 2.95 1 PMID:18757371 -3.1.4.16 cyclic 2',3'-amp mycobacterium tuberculosis 2.8 2.8 1 PMID:18757371 -3.1.4.16 cyclic 2',3'-amp myxococcus xanthus 0.0006 0.0006 1 PMID:19114044 -3.1.4.16 diphosphate escherichia coli 2.51 2.51 1 PMID:15210699 -3.1.4.16 nadp escherichia coli 14.9 14.9 1 PMID:15210699 -3.1.4.16 p-nitrophenyl phosphate escherichia coli 10.3 6.65 2 PMID:15210699;PMID:18757371 -3.1.4.16 p-nitrophenyl phosphate mycobacterium tuberculosis 0.55 0.55 1 PMID:18757371 -3.1.4.16 papa escherichia coli 1.3 0.6502 2 PMID:33671286 -3.1.4.17 2',3'-camp myxococcus xanthus 0.00096 0.00078 2 PMID:19114044 -3.1.4.17 3',5'-camp corynebacterium glutamicum 18.1 18.1 1 PMID:27862445 -3.1.4.17 3',5'-camp drosophila melanogaster 0.00206 0.00206 1 PMID:25648146 -3.1.4.17 3',5'-camp homo sapiens 0.52 0.49 4 PMID:15938621;PMID:16172121 -3.1.4.17 3',5'-camp myxococcus xanthus 0.00096 0.0009450000000000001 2 PMID:19114044 -3.1.4.17 3',5'-camp saccharomyces cerevisiae 21.0 16.9 5 PMID:25050706 -3.1.4.17 3',5'-cgmp drosophila melanogaster 0.00123 0.00123 1 PMID:25648146 -3.1.4.17 3',5'-cgmp homo sapiens 4.2 4.2 1 PMID:15938621 -3.1.4.17 3',5'-cgmp saccharomyces cerevisiae 15.1 11.8 5 PMID:25050706 -3.1.4.17 5'-amp myxococcus xanthus 0.00551 0.004305 2 PMID:19114044 -3.1.4.17 5'-atp myxococcus xanthus 0.00454 0.003045 2 PMID:19114044 -3.1.4.17 5'-papa thermotoga maritima 0.14 0.14 1 PMID:29107484 -3.1.4.17 5'-papg thermotoga maritima 0.26 0.26 1 PMID:29107484 -3.1.4.17 camp bos taurus 567.0 567.0 1 PMID:6313664 -3.1.4.17 cgmp bos taurus 667.0 667.0 1 PMID:6313664 -3.1.4.2 4-nitrophenyl ethylphosphonate klebsiella aerogenes 0.5 0.5 1 PMID:17630782 -3.1.4.2 4-nitrophenyl methylphosphonate klebsiella aerogenes 1.6 1.6 1 PMID:17630782 -3.1.4.2 4-nitrophenyl phenyl phosphate klebsiella aerogenes 4.0 4.0 1 PMID:17630782 -3.1.4.2 4-nitrophenyl phenyl phosphonate klebsiella aerogenes 2.8 2.8 1 PMID:17630782 -3.1.4.2 bis(4-nitrophenyl) phosphate klebsiella aerogenes 6.0 6.0 1 PMID:17630782 -3.1.4.2 choline lysoplasmalogen thermocrispum sp. rd004668 70.6 70.6 1 PMID:27833852 -3.1.4.2 diethyl phosphate klebsiella aerogenes 0.0074 0.0074 1 PMID:17630782 -3.1.4.2 dimethyl phosphate klebsiella aerogenes 0.005 0.005 1 PMID:17630782 -3.1.4.2 ethyl 4-nitrophenyl phosphate klebsiella aerogenes 2.0 2.0 1 PMID:17630782 -3.1.4.2 ethyl methylphosphonate klebsiella aerogenes 0.0012 0.0012 1 PMID:17630782 -3.1.4.2 isobutyl methylphosphonate klebsiella aerogenes 0.001 0.001 1 PMID:17630782 -3.1.4.2 isopropyl 4-nitrophenyl phosphate klebsiella aerogenes 1.0 1.0 1 PMID:17630782 -3.1.4.2 isopropyl methylphosphonate klebsiella aerogenes 0.001 0.001 1 PMID:17630782 -3.1.4.2 methyl 4-nitrophenyl phosphate klebsiella aerogenes 7.3 7.3 1 PMID:17630782 -3.1.4.2 o-ethyl s-[2-(ethylsulfanyl)ethyl] hydrogen thiophosphate klebsiella aerogenes 0.0012 0.0012 1 PMID:17630782 -3.1.4.2 phenyl methylphosphonate klebsiella aerogenes 0.0031 0.0031 1 PMID:17630782 -3.1.4.2 s-[2-[bis(1-methylethyl)amino]ethyl] o-ethyl hydrogen thiophosphate klebsiella aerogenes 1.1 1.1 1 PMID:17630782 -3.1.4.2 sn-glycero 3-phosphorylcholine escherichia coli 220.0 220.0 1 PMID:2829735 -3.1.4.3 1,2-dibutyryl-sn-glycero-3-phosphocholine listeria monocytogenes 8.0 8.0 1 PMID:26976751 -3.1.4.3 1,2-diheptanoyl-sn-glycero-3-phosphocholine listeria monocytogenes 8.5 8.5 1 PMID:26976751 -3.1.4.3 1,2-dihexanoyl-sn-glycero-3-phosphocholine listeria monocytogenes 12.8 12.8 1 PMID:26976751 -3.1.4.3 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine streptomyces sp. na684 4000.0 4000.0 1 PMID:25900053 -3.1.4.3 4-nitrophenylphosphorycholine bacillus cereus 155.0 155.0 1 PMID:35772600 -3.1.4.3 4-nitrophenylphosphorylcholine bacillus cereus 3.9 3.9 1 * -3.1.4.3 diheptanoylphosphatidylcholine bacillus cereus 13.8 10.325 2 PMID:9521750 -3.1.4.3 dihexanoylphosphatidic acid bacillus cereus 0.0198 0.0144 2 PMID:9521750 -3.1.4.3 dihexanoylphosphatidylcholine bacillus cereus 6.78 5.855 2 PMID:9521750 -3.1.4.3 l-alpha-lysophosphatidylcholine streptomyces sp. na684 243.0 243.0 1 PMID:25900053 -3.1.4.3 p-nitrophenylphosphorylcholine pseudomonas aeruginosa 979.0 979.0 1 PMID:12410824 -3.1.4.35 3',5'-cgmp bos taurus 0.55 0.55 1 PMID:19798052 -3.1.4.35 3',5'-cgmp homo sapiens 4400.0 4400.0 1 PMID:19801642 -3.1.4.35 cgmp homo sapiens 2.2 2.2 1 PMID:17979301 -3.1.4.37 2',3'-camp escherichia coli 7.63 7.63 1 PMID:15210699 -3.1.4.37 2',3'-camp mus musculus 118.0 118.0 1 PMID:20180985 -3.1.4.37 2',3'-cgmp escherichia coli 1.97 1.97 1 PMID:15210699 -3.1.4.37 2',3'-cnadp rattus norvegicus 1690.0 1200.0 3 PMID:11278504 -3.1.4.37 2',3'-cnadp+ mus musculus 940.0 940.0 1 PMID:26563764 -3.1.4.37 2',3'-cyclic amp mus musculus 940.0 940.0 1 PMID:23831225 -3.1.4.37 2'-amp escherichia coli 3.09 3.09 1 PMID:15210699 -3.1.4.37 adp escherichia coli 1.24 1.24 1 PMID:15210699 -3.1.4.37 atp escherichia coli 3.78 3.78 1 PMID:15210699 -3.1.4.37 cdp escherichia coli 4.83 4.83 1 PMID:15210699 -3.1.4.37 ctp escherichia coli 3.36 3.36 1 PMID:15210699 -3.1.4.37 cyclic 2',3'-amp acetivibrio thermocellus 8.9 8.9 1 PMID:17986465 -3.1.4.37 cyclic 2',3'-amp escherichia coli 7.63 4.07 2 PMID:15210699 -3.1.4.37 cyclic 2',3'-gmp escherichia coli 2.94 2.455 2 PMID:15210699 -3.1.4.37 diphosphate escherichia coli 2.51 2.51 1 PMID:15210699 -3.1.4.37 nadp escherichia coli 14.9 14.9 1 PMID:15210699 -3.1.4.37 p-nitrophenyl phosphate escherichia coli 10.3 10.3 1 PMID:15210699 -3.1.4.38 4-nitrophenyl phosphocholine bos taurus 2.0 2.0 1 PMID:23161088 -3.1.4.38 lysophosphatidylcholine bos taurus 2.5 2.5 1 PMID:23161088 -3.1.4.38 lysosphingomyelin bos taurus 65.0 65.0 1 PMID:23161088 -3.1.4.38 sn-glycero-3-phosphocholine bos taurus 1.0 1.0 1 PMID:23161088 -3.1.4.38 sn-glycerol-3-phosphocholine streptomyces sanglieri 29.0 29.0 1 PMID:24211038 -3.1.4.39 1-lauroyl-2-hydroxy-sn-glycero-3-phosphocholine mus musculus 23.0 11.536 2 PMID:34523685 -3.1.4.39 1-linoleoyl-2-hydroxy-sn-glycero-sn-3-phosphocholine mus musculus 13.0 6.521 2 PMID:34523685 -3.1.4.39 1-myristoyl-2-hydroxy-sn-glycero-3-phosphocholine mus musculus 15.0 7.5265 2 PMID:34523685 -3.1.4.39 1-o-(9z)-octadecenyl-2-hydroxy-sn-glycero-3-phosphocholine mus musculus 48.0 24.075 2 PMID:34523685 -3.1.4.39 1-o-1'-(z)-hexadecenyl-2-hydroxy-sn-glycero-3-phosphocholine mus musculus 9.0 4.548 2 PMID:34523685 -3.1.4.39 1-o-1'-(z)-octadecenyl-2-hydroxy-sn-glycero-3-phosphocholine mus musculus 4.9 2.52 2 PMID:34523685 -3.1.4.39 1-o-alkyl-sn-glycero-3-phosphocholine mus musculus 0.077 0.077 1 PMID:25528375 -3.1.4.39 1-o-hexadecyl-2-hydroxy-sn-glycero-3-phosphocholine mus musculus 14.0 7.06 2 PMID:34523685 -3.1.4.39 1-o-octadecyl-2-hydroxy-sn-glycero-3-phosphocholine mus musculus 4.9 2.52 2 PMID:34523685 -3.1.4.39 1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine mus musculus 16.0 8.0135 2 PMID:34523685 -3.1.4.39 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine mus musculus 19.0 9.52 2 PMID:34523685 -3.1.4.39 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine mus musculus 0.18 0.18 1 PMID:34523685 -3.1.4.39 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoglycerol mus musculus 0.015 0.015 1 PMID:34523685 -3.1.4.39 1-palmitoyl-2-hydroxy-snglycero-3-phosphoserine mus musculus 0.09 0.09 1 PMID:34523685 -3.1.4.39 1-stearoyl-2-hydroxy-sn-glycero-3-phosphocholine mus musculus 3.4 1.7065 2 PMID:34523685 -3.1.4.39 lysophosphatidylcholine mus musculus 0.032 0.032 1 PMID:25528375 -3.1.4.4 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine streptomyces sp. na684 4000.0 4000.0 1 PMID:25900053 -3.1.4.4 egg phosphatidylcholine streptomyces hiroshimensis 67.58 67.58 1 PMID:36619468 -3.1.4.4 l-alpha-lysophosphatidylcholine streptomyces sp. na684 243.0 243.0 1 PMID:25900053 -3.1.4.4 l-alpha-phosphatidylcholine moritella sp. jt01 1.72 1.72 1 PMID:36232620 -3.1.4.4 phosphatidyl-p-nitrophenol streptomyces septatus 174.8 121.80000000000001 2 PMID:15899903 -3.1.4.4 phosphatidylcholine rattus norvegicus 0.93 0.17 17 PMID:16339153 -3.1.4.4 yolk phosphatidylcholine streptomyces cinnamoneus 67.6 67.6 1 PMID:34585426 -3.1.4.41 sphingomyelin loxosceles intermedia 0.118 0.088 2 PMID:16458340 -3.1.4.41 sphingomyelin loxosceles laeta 0.0175 0.0052499999999999995 4 PMID:19249326 -3.1.4.45 4-nitrophenyl alpha-n-acetyl-d-glucosaminide clostridium perfringens 0.26 0.26 1 PMID:18443291 -3.1.4.45 dinitrophenyl alpha-n-acetyl-dglucosaminide clostridium perfringens 8.5 8.5 1 PMID:18443291 -3.1.4.46 bis(4-nitrophenyl) phosphate bacillus altitudinis 1.42 1.42 1 PMID:33758739 -3.1.4.46 bis(p-nitrophenyl phosphate) klebsiella aerogenes 2.78 1.478 2 PMID:18678932 -3.1.4.46 bis(p-nitrophenyl) phosphate klebsiella aerogenes 2.0 1.4 3 PMID:19923005 -3.1.4.46 glycerophosphocholine escherichia coli 3.2 3.2 1 PMID:18083802 -3.1.4.46 glycerophosphocholine escherichia coli k-12 3.2 3.2 1 * -3.1.4.46 glycerophosphoethanolamine escherichia coli 1.1 1.1 1 PMID:18083802 -3.1.4.46 glycerophosphoethanolamine escherichia coli k-12 1.1 1.1 1 * -3.1.4.46 glycerophosphoglycerol escherichia coli 3.3 3.3 1 PMID:18083802 -3.1.4.46 glycerophosphoglycerol escherichia coli k-12 3.3 3.3 1 * -3.1.4.46 glycerophosphoinositol escherichia coli 1.8 1.8 1 PMID:18083802 -3.1.4.46 glycerophosphoinositol escherichia coli k-12 1.8 1.8 1 * -3.1.4.46 glycerophosphoserine escherichia coli 2.8 2.8 1 PMID:18083802 -3.1.4.46 glycerophosphoserine escherichia coli k-12 2.8 2.8 1 * -3.1.4.46 p-nitrophenyl phosphate klebsiella aerogenes 1.89 1.89 1 PMID:18831553 -3.1.4.52 3'3'-cyclic gmp-amp vibrio cholerae serotype o1 0.153 0.153 1 PMID:31647518 -3.1.4.52 5'-phosphoguanylyl(3'->5')guanosine pseudomonas aeruginosa 0.00077 0.0002 3 PMID:24066157 -3.1.4.52 cyclic di-3',5'-guanylate klebsiella pneumoniae 6.7 1.505 8 PMID:19536266 -3.1.4.52 cyclic di-3',5'-guanylate pseudomonas aeruginosa 0.67 0.39 5 PMID:18344366;PMID:19376848;PMID:24066157 -3.1.4.52 cyclic di-3',5'-guanylate thermosynechococcus vestitus 0.28 0.28 1 PMID:32224605 -3.1.4.52 cyclic di-3',5'-guanylate vibrio cholerae serotype o1 0.157 0.157 1 PMID:31647518 -3.1.4.52 cyclic-di-gmp pseudomonas aeruginosa 0.67 0.67 1 PMID:18344366 -3.1.4.53 3',5'-camp homo sapiens 4.0 4.0 1 PMID:18983167 -3.1.4.53 3',5'-camp myxococcus xanthus 0.00096 0.0009450000000000001 2 PMID:19114044 -3.1.4.53 3',5'-cgmp homo sapiens 1.6 1.6 1 PMID:18983167 -3.1.4.53 camp homo sapiens 6.7 1.56 5 PMID:12071709;PMID:17727341 -3.1.4.53 cgmp homo sapiens 1.19 0.835 2 PMID:17727341 -3.1.4.55 2',3'-camp escherichia coli 1.71 1.71 1 PMID:19366688 -3.1.4.55 2',3'-ccmp escherichia coli 0.64 0.64 1 PMID:19366688 -3.1.4.55 2',3'-cgmp escherichia coli 1.23 1.23 1 PMID:19366688 -3.1.4.55 bis(p-nitrophenyl)phosphate escherichia coli 4.1 1.13 4 PMID:19366688;PMID:21830807 -3.1.4.55 thymidine 5'-monophosphate p-nitrophenyl ester escherichia coli 0.08 0.08 1 PMID:19366688 -3.1.4.57 5-phospho-alpha-d-ribose 1,2-cyclic phosphate eggerthella lenta 2.0 2.0 1 PMID:24147537 -3.1.4.57 d-ribofuranose 2,5-bisphosphate eggerthella lenta 7.4 7.4 1 PMID:24147537 -3.1.4.59 2',3'-camp streptococcus suis 290.51 290.51 1 PMID:35391727 -3.1.4.59 2',3'-ccmp streptococcus suis 373.45 373.45 1 PMID:35391727 -3.1.4.59 2',3'-cgamp streptococcus suis 0.01 0.01 1 PMID:35391727 -3.1.4.59 2',3'-cgmp streptococcus suis 318.3 318.3 1 PMID:35391727 -3.1.4.59 2',3'-cump streptococcus suis 748.84 748.84 1 PMID:35391727 -3.1.4.59 3',3'-cgamp streptococcus suis 0.28 0.28 1 PMID:35391727 -3.1.4.59 3'-amp streptococcus suis 323.76 323.76 1 PMID:35391727 -3.1.4.59 3'-gmp streptococcus suis 666.55 666.55 1 PMID:35391727 -3.1.4.59 3'-ump streptococcus suis 573.53 573.53 1 PMID:35391727 -3.1.4.59 4-nphp streptococcus suis 4.98 4.98 1 PMID:35391727 -3.1.4.59 adp streptococcus suis 0.17 0.17 1 PMID:35391727 -3.1.4.59 adp-ribose streptococcus suis 0.08 0.08 1 PMID:35391727 -3.1.4.59 ap3a streptococcus suis 0.29 0.29 1 PMID:35391727 -3.1.4.59 ap4a streptococcus suis 0.29 0.29 1 PMID:35391727 -3.1.4.59 atp streptococcus suis 0.85 0.85 1 PMID:35391727 -3.1.4.59 bis-4nphp streptococcus suis 273.66 273.66 1 PMID:35391727 -3.1.4.59 c-di-gmp streptococcus suis 0.06 0.06 1 PMID:35391727 -3.1.4.59 cyclic di-3',5'-adenylate bacillus subtilis 0.55 0.55 1 PMID:19901023 -3.1.4.59 cyclic di-3',5'-adenylate mycolicibacterium smegmatis 0.52 0.52 1 PMID:26078723 -3.1.4.59 cyclic di-3',5'-adenylate streptococcus suis 1.65 1.65 1 PMID:35391727 -3.1.4.59 cyclic di-3',5'-guanylate bacillus subtilis 0.23 0.23 1 PMID:19901023 -3.1.4.59 cyclic di-3',5'-guanylate mycolicibacterium smegmatis 0.03 0.03 1 PMID:26078723 -3.1.4.59 papa streptococcus suis 19.33 19.33 1 PMID:35391727 -3.1.4.59 pgpg streptococcus suis 0.76 0.76 1 PMID:35391727 -3.1.4.60 5'-o-phosphonoadenylyl-(3'->5')-adenosine streptococcus mitis 3527.0 3527.0 1 PMID:32825526 -3.1.4.60 cyclic-di-3',5'-adenylate streptococcus mitis 0.078 0.078 1 PMID:32825526 -3.1.5.1 dgtp escherichia coli 4000.0 4000.0 1 PMID:2826481 -3.1.5.1 dgtp leeuwenhoekiella blandensis 2.6 2.6 1 PMID:35643313 -3.1.6.1 4-ethylphenyl sulfate helix pomatia 7150.0 7150.0 1 PMID:30738652 -3.1.6.1 4-methylumbelliferyl sulfate helix pomatia 28600.0 28600.0 1 PMID:30738652 -3.1.6.1 4-nitrophenyl phosphate pseudomonas aeruginosa 0.023 0.023 1 PMID:19554727 -3.1.6.1 4-nitrophenyl sulfate helix pomatia 90.83 47.415 12 * -3.1.6.1 4-nitrophenyl sulfate pseudoalteromonas carrageenovora 256.9 256.9 1 PMID:27746358 -3.1.6.1 4-nitrophenyl sulfate pseudomonas aeruginosa 14.2 14.2 1 PMID:19554727 -3.1.6.1 4-nitrophenyl sulfate serratia sp. sm1 1.62 1.34 5 PMID:34952364 -3.1.6.1 estrone 3-sulfate helix pomatia 40900.0 40900.0 1 PMID:30738652 -3.1.6.1 ferulic acid 4-sulfate helix pomatia 138.0 138.0 1 PMID:30738652 -3.1.6.1 indoxyl sulfate helix pomatia 228.0 228.0 1 PMID:30738652 -3.1.6.1 methylurolithin a sulfate helix pomatia 88500.0 88500.0 1 PMID:30738652 -3.1.6.1 n-acetyltyramine sulfate helix pomatia 1800.0 1800.0 1 PMID:30738652 -3.1.6.1 p-coumaric acid sulfate helix pomatia 235.0 235.0 1 PMID:30738652 -3.1.6.1 p-cresyl sulfate helix pomatia 871.0 871.0 1 PMID:30738652 -3.1.6.1 p-nitrophenyl sulfate pseudoalteromonas carrageenovora 1000.0 1000.0 1 PMID:15596366 -3.1.6.1 resorcinol sulfate helix pomatia 92.0 92.0 1 PMID:30738652 -3.1.6.1 vanillic acid 4-sulfate helix pomatia 119.0 119.0 1 PMID:30738652 -3.1.6.12 nitrocatechol sulfate bos taurus 143.0 143.0 1 PMID:1009120 -3.1.6.19 (2r)-octan-2-yl hydrogen sulfate pseudomonas sp. dsm 6611 4.37 4.37 1 PMID:23061549 -3.1.6.2 dehydroepiandrosterone sulfate homo sapiens 6.48 6.48 1 PMID:11738554 -3.1.6.21 sds pseudomonas sp. s9 4.88 4.88 1 PMID:28442601 -3.1.6.6 4-methylumbelliferyl sulfate sinorhizobium meliloti 0.043 0.043 1 PMID:30338300 -3.1.6.6 4-nitrophenyl methylphosphate sinorhizobium meliloti 0.004 0.004 2 PMID:29458126 -3.1.6.6 4-nitrophenyl methylphosphonate sinorhizobium meliloti 0.1 0.1 2 PMID:29458126 -3.1.6.6 4-nitrophenyl sulfate sinorhizobium meliloti 0.22 0.22 3 PMID:29458126;PMID:30338300 -3.1.6.6 choline o-sulfate sinorhizobium meliloti 2.4 2.4 1 PMID:29458126 -3.1.6.6 choline sulfate sinorhizobium meliloti 0.27 0.27 1 PMID:30338300 -3.1.6.6 choline-o-sulfate sinorhizobium meliloti 2.4 2.4 1 PMID:29458126 -3.1.6.6 phosphoryl choline sinorhizobium meliloti 0.027 0.027 1 PMID:29458126 -3.1.6.8 4-methylumbelliferyl sulfate homo sapiens 0.817 0.817 1 PMID:804474 -3.1.6.8 4-nitrocatechol sulfate homo sapiens 16.8 16.8 1 PMID:804474 -3.1.6.8 cerebroside 3-sulfate homo sapiens 1.45 1.45 1 PMID:804474 -3.1.7.11 geranyl diphosphate ocimum basilicum 0.8 0.8 1 PMID:14657409 -3.1.7.2 ppgpp mycobacterium tuberculosis 6.0 4.485 2 PMID:10995231 -3.1.7.6 (2e,6e)-farnesyl diphosphate saccharolobus solfataricus 2.09 2.09 1 PMID:32732034 -3.1.7.6 geranylgeranyl diphosphate saccharolobus solfataricus 4.57 3.12 2 PMID:32732034 -3.1.8.1 (1e)-but-1-en-1-yl dibutyl phosphate sphingobium sp. tcm1 0.83 0.83 1 PMID:30730705 -3.1.8.1 (s)-[2-[di(propan-2-yl)amino]ethyl] o,o-diethyl phosphorothioate brevundimonas diminuta 1.1 1.1 1 PMID:26274608 -3.1.8.1 1,2,2-trimethylpropyl methylphosphonofluoridate brevundimonas diminuta 5.0 5.0 1 PMID:2154956 -3.1.8.1 2,4-dinitrophenyl diethyl phosphate homo sapiens 9160.0 4580.135 2 PMID:15835926 -3.1.8.1 2,6-difluorophenyl diethyl phosphate homo sapiens 950.0 475.031 2 PMID:15835926 -3.1.8.1 2-ethylhexyl diphenyl phosphate sphingopyxis terrae subsp. terrae 1.61 1.61 1 PMID:36107214 -3.1.8.1 2-fluoro 4-nitrophenyl diethyl phosphate homo sapiens 3.7 3.7 1 PMID:15835926 -3.1.8.1 2-fluoro-4-nitrophenyl diethyl phosphate homo sapiens 11080.0 11080.0 1 PMID:15835926 -3.1.8.1 3,5-dinitrophenyl diethyl phosphate homo sapiens 1477.0 743.6 2 PMID:15835926 -3.1.8.1 3-cyanophenyl diethyl phosphate homo sapiens 1610.0 805.089 2 PMID:15835926 -3.1.8.1 3-fluoro 4-nitrophenyl diethyl phosphate homo sapiens 13.9 13.9 1 PMID:15835926 -3.1.8.1 3-fluoro-4-nitrophenyl diethyl phosphate homo sapiens 11680.0 11680.0 1 PMID:15835926 -3.1.8.1 3-fluorophenyl diethyl phosphate homo sapiens 656.0 328.00055 2 PMID:15835926 -3.1.8.1 3-nitrophenyl diethyl phosphate homo sapiens 840.0 420.038 2 PMID:15835926 -3.1.8.1 4-acetoxy acetophenone homo sapiens 13.0 13.0 1 PMID:15835926 -3.1.8.1 4-acetylphenyl (2r)-3,3-dimethylbutan-2-yl (r)-methylphosphonate homo sapiens 3.4 3.4 1 PMID:20701311 -3.1.8.1 4-acetylphenyl (2r)-3,3-dimethylbutan-2-yl (s)-methylphosphonate homo sapiens 0.45 0.45 1 PMID:20701311 -3.1.8.1 4-acetylphenyl (2s)-3,3-dimethylbutan-2-yl (s)-methylphosphonate homo sapiens 0.016 0.016 1 PMID:20701311 -3.1.8.1 4-acetylphenyl (r)-2-methylpropyl methylphosphonate brevundimonas diminuta 84.0 84.0 1 PMID:26274608 -3.1.8.1 4-acetylphenyl (s)-2-methylpropyl methylphosphonate brevundimonas diminuta 25.0 25.0 1 PMID:26274608 -3.1.8.1 4-acetylphenyl 2-methylpropyl (r)-methylphosphonate homo sapiens 93.0 93.0 1 PMID:20701311 -3.1.8.1 4-acetylphenyl 2-methylpropyl (s)-methylphosphonate homo sapiens 22.0 22.0 1 PMID:20701311 -3.1.8.1 4-acetylphenyl cyclohexyl methyl (r)-phosphate sphingobium sp. tcm1 0.36 0.36 1 PMID:29513982 -3.1.8.1 4-acetylphenyl cyclohexyl methyl (s)-phosphate sphingobium sp. tcm1 0.38 0.38 1 PMID:29513982 -3.1.8.1 4-acetylphenyl ethyl (r)-methylphosphonate homo sapiens 150.0 150.0 1 PMID:20701311 -3.1.8.1 4-acetylphenyl ethyl (s)-methylphosphonate homo sapiens 670.0 670.0 1 PMID:20701311 -3.1.8.1 4-acetylphenyl propan-2-yl (r)-methylphosphonate homo sapiens 100.0 100.0 1 PMID:20701311 -3.1.8.1 4-acetylphenyl propan-2-yl (s)-methylphosphonate homo sapiens 40.0 40.0 1 PMID:20701311 -3.1.8.1 4-carbamoylphenyl diethyl phosphate sphingobium sp. tcm1 0.8 0.8 1 PMID:30730705 -3.1.8.1 4-chlorophenyl diethyl phosphate homo sapiens 848.0 424.0004 2 PMID:15835926 -3.1.8.1 4-cyanophenyl diethyl phosphate homo sapiens 7495.0 3747.7 2 PMID:15835926 -3.1.8.1 4-diethyl phosphate acetophenone homo sapiens 8080.0 4040.22 2 PMID:15835926 -3.1.8.1 4-diethyl phosphate benzaldehyde homo sapiens 12620.0 6310.235 2 PMID:15835926 -3.1.8.1 4-diethyl phosphate methyl benzoate homo sapiens 5485.0 5485.0 1 PMID:15835926 -3.1.8.1 4-nitrophenyl diethyl phosphate homo sapiens 10520.0 5262.4 2 PMID:15835926 -3.1.8.1 5-(thiobutyryl)butyrolactone homo sapiens 166.0 166.0 1 PMID:16407305 -3.1.8.1 benzyl acetate homo sapiens 0.02 0.02 1 PMID:15835926 -3.1.8.1 chlorpyrifos escherichia coli k-12 30900.0 3075.0 8 PMID:15294802 -3.1.8.1 cmp-coumarin sulfolobus acidocaldarius 0.28 0.28 1 PMID:24894602 -3.1.8.1 coumaphos purpureocillium lilacinum 949.0 949.0 1 * -3.1.8.1 cyclohexyl ethyl 4-nitrophenyl (r)-phosphate sphingobium sp. tcm1 2.5 2.5 1 PMID:29513982 -3.1.8.1 cyclohexyl ethyl 4-nitrophenyl (s)-phosphate sphingobium sp. tcm1 2.8 2.8 1 PMID:29513982 -3.1.8.1 cyclohexyl methyl 4-nitrophenyl (r)-phosphate sphingobium sp. tcm1 6.0 6.0 1 PMID:29513982 -3.1.8.1 cyclohexyl methyl 4-nitrophenyl (s)-phosphate sphingobium sp. tcm1 1.11 1.11 1 PMID:29513982 -3.1.8.1 cyclohexyl methyl phenyl (r)-phosphate sphingobium sp. tcm1 0.38 0.38 1 PMID:29513982 -3.1.8.1 demeton-s brevundimonas diminuta 3.5 3.5 1 PMID:18434422 -3.1.8.1 demeton-s geobacillus stearothermophilus 0.0006 0.0006 1 PMID:19615330 -3.1.8.1 demeton-s purpureocillium lilacinum 650.0 650.0 1 * -3.1.8.1 demeton-s methyl flavobacterium sp. 13.16 13.16 1 PMID:20132373 -3.1.8.1 dibutyl 2,2,3,3-tetrafluorobutyl phosphate sphingobium sp. tcm1 0.36 0.20249999999999999 2 PMID:30730705 -3.1.8.1 dibutyl 3,3-difluorobutyl phosphate sphingobium sp. tcm1 0.043 0.043 1 PMID:30730705 -3.1.8.1 dibutyl 4-acetophenyl phosphate sphingobium sp. tcm1 2.5 2.5 1 PMID:30730705 -3.1.8.1 dibutyl 4-nitrophenyl phosphate sphingobium sp. tcm1 7.5 7.5 1 PMID:30730705 -3.1.8.1 dibutyl phenyl phosphate sphingobium sp. tcm1 4.4 4.4 1 PMID:30730705 -3.1.8.1 diethyl 2,4,6-trifluorophenyl phosphate sphingobium sp. tcm1 71.0 71.0 1 PMID:30730705 -3.1.8.1 diethyl 2,4-difluorophenyl phosphate sphingobium sp. tcm1 13.0 13.0 1 PMID:30730705 -3.1.8.1 diethyl 2,6-difluoro-4-nitrophenyl phosphate sphingobium sp. tcm1 93.0 93.0 1 PMID:30730705 -3.1.8.1 diethyl 2-fluoro-4-nitrophenyl phosphate sphingobium sp. tcm1 40.0 40.0 1 PMID:30730705 -3.1.8.1 diethyl 2-fluorophenyl phosphate sphingobium sp. tcm1 21.0 21.0 1 PMID:30730705 -3.1.8.1 diethyl 3-fluoro-4-nitrophenyl phosphate sphingobium sp. tcm1 107.0 107.0 1 PMID:30730705 -3.1.8.1 diethyl 3-fluorophenyl phosphate sphingobium sp. tcm1 81.0 81.0 1 PMID:30730705 -3.1.8.1 diethyl 4-acetophenyl phosphate sphingobium sp. tcm1 0.6 0.6 1 PMID:30730705 -3.1.8.1 diethyl 4-chlorophenyl phosphate brevundimonas diminuta 0.36 0.23 3 PMID:15134445 -3.1.8.1 diethyl 4-chlorophenyl phosphate sphingobium sp. tcm1 40.0 40.0 1 PMID:30730705 -3.1.8.1 diethyl 4-chlorophenyl thiophosphate brevundimonas diminuta 2.4 2.2 3 PMID:15134445 -3.1.8.1 diethyl 4-cyanophenyl phosphate sphingobium sp. tcm1 93.0 93.0 1 PMID:30730705 -3.1.8.1 diethyl 4-fluorophenyl phosphate sphingobium sp. tcm1 78.0 78.0 1 PMID:30730705 -3.1.8.1 diethyl 4-formylphenyl phosphate sphingobium sp. tcm1 31.0 31.0 1 PMID:30730705 -3.1.8.1 diethyl 4-methoxyphenyl phosphate sphingobium sp. tcm1 2.5 2.5 1 PMID:30730705 -3.1.8.1 diethyl 4-nitrophenyl phosphate brevundimonas diminuta 2500.0 2300.0 3 PMID:15134445 -3.1.8.1 diethyl 4-nitrophenyl phosphate sphingobium sp. tcm1 32.0 19.25 2 PMID:29513982;PMID:30730705 -3.1.8.1 diethyl paraoxon homo sapiens 5.7 5.0 2 PMID:21382471 -3.1.8.1 diethyl paraoxon oryctolagus cuniculus 16.2 16.2 1 PMID:21382471 -3.1.8.1 diethyl pentafluoro-phenyl phosphate sphingobium sp. tcm1 167.0 167.0 1 PMID:30730705 -3.1.8.1 diethyl phenyl phosphate sphingobium sp. tcm1 71.0 71.0 1 PMID:30730705 -3.1.8.1 diethyl-paraoxon brevundimonas diminuta 2230.0 2230.0 1 PMID:26274608 -3.1.8.1 diethyl-paraoxon homo sapiens 0.202 0.153 2 PMID:27838376 -3.1.8.1 diisopropylfluorophosphate brevundimonas diminuta 41.0 41.0 1 PMID:2154956 -3.1.8.1 dimethyl 4-nitrophenyl phosphate sphingobium sp. tcm1 9.1 9.1 1 PMID:29513982 -3.1.8.1 dimethyl-paraoxon homo sapiens 0.9 0.9 1 PMID:26829396 -3.1.8.1 ethyl acetate homo sapiens 0.24 0.24 1 PMID:15835926 -3.1.8.1 ethyl paraoxon geobacillus stearothermophilus 0.115 0.115 1 PMID:19615330 -3.1.8.1 ethyl-paraoxon vulcanisaeta moutnovskia 0.00108 0.00108 1 PMID:25670483 -3.1.8.1 isopropylmethylphosphonofluoridate brevundimonas diminuta 56.0 56.0 1 PMID:2154956 -3.1.8.1 malathion brevundimonas diminuta 0.047 0.047 1 PMID:30893549 -3.1.8.1 malathion flavobacterium sp. 2.55 2.55 1 PMID:20132373 -3.1.8.1 malathion purpureocillium lilacinum 160.0 160.0 1 * -3.1.8.1 malathion saccharolobus islandicus 6.2 6.2 1 PMID:23071703 -3.1.8.1 malathion saccharolobus solfataricus 0.00089 0.00089 1 PMID:23139857 -3.1.8.1 methyl 4-[(diethoxyphosphoryl)oxy]benzoate sphingobium sp. tcm1 3.2 3.2 1 PMID:30730705 -3.1.8.1 methyl 4-nitrophenyl phenyl (r)-phosphate sphingobium sp. tcm1 6.3 6.3 1 PMID:29513982 -3.1.8.1 methyl 4-nitrophenyl phenyl (s)-phosphate sphingobium sp. tcm1 0.6 0.6 1 PMID:29513982 -3.1.8.1 methyl 4-nitrophenyl propan-2-yl (r)-phosphate sphingobium sp. tcm1 5.0 5.0 1 PMID:29513982 -3.1.8.1 methyl 4-nitrophenyl propan-2-yl (s)-phosphate sphingobium sp. tcm1 2.05 2.05 1 PMID:29513982 -3.1.8.1 methyl bis(4-nitrophenyl) phosphate sphingobium sp. tcm1 9.0 9.0 1 PMID:29513982 -3.1.8.1 methyl paraoxon geobacillus stearothermophilus 0.00783 0.00783 1 PMID:19615330 -3.1.8.1 methyl paraoxon saccharolobus islandicus 7.4 7.4 1 PMID:23071703 -3.1.8.1 methyl paraoxon saccharolobus solfataricus 342.0 2.71 3 PMID:15909078;PMID:18931117;PMID:23139857 -3.1.8.1 methyl paraoxon sulfolobus acidocaldarius 14.05 7.75 3 PMID:17337320;PMID:23174457;PMID:24894602 -3.1.8.1 methyl paraoxon vulcanisaeta moutnovskia 1.25 1.25 1 PMID:24858677 -3.1.8.1 methyl parathion purpureocillium lilacinum 1152.0 1152.0 1 * -3.1.8.1 methyl parathion saccharolobus islandicus 9.7 9.7 1 PMID:23071703 -3.1.8.1 methyl parathion saccharolobus solfataricus 0.0011 0.0011 1 PMID:23139857 -3.1.8.1 methylparathion escherichia coli 2300.0 2300.0 1 PMID:16423845 -3.1.8.1 o,o,s-tributyl phosphorothioate sphingobium sp. tcm1 0.42 0.42 1 PMID:30730705 -3.1.8.1 o-isobutyl-s-[2-(diethylamino)ethyl]methylphosphonothioic acid homo sapiens 0.1 0.1 1 PMID:20176005 -3.1.8.1 paraoxon brevundimonas diminuta 10500.0 2215.0 14 PMID:15790580;PMID:16188223;PMID:16808151;PMID:18434422;PMID:19548794;PMID:2154956 -3.1.8.1 paraoxon escherichia coli 11700.0 11700.0 1 PMID:16423845 -3.1.8.1 paraoxon homo sapiens 10.98 1.09 25 PMID:14695884;PMID:16128586;PMID:16407305;PMID:1673383;PMID:18951406;PMID:20176005;PMID:24123308;PMID:25107406;PMID:33348669 -3.1.8.1 paraoxon mus musculus 0.0008 0.0008 1 PMID:14695884 -3.1.8.1 paraoxon oryctolagus cuniculus 0.001 0.001 1 PMID:14695884 -3.1.8.1 paraoxon purpureocillium lilacinum 1336.0 1336.0 1 * -3.1.8.1 paraoxon saccharolobus islandicus 14.31 2.06 4 PMID:23071703 -3.1.8.1 paraoxon saccharolobus solfataricus 597.0 3.135 6 PMID:15909078;PMID:18931117;PMID:20667718;PMID:21183649;PMID:23139857 -3.1.8.1 paraoxon sulfolobus acidocaldarius 8.52 8.52 1 PMID:23174457 -3.1.8.1 paraoxon-ethyl brevundimonas diminuta 311.6 311.6 1 * -3.1.8.1 parathion brevundimonas diminuta 720.0 600.0 3 PMID:15134445 -3.1.8.1 parathion purpureocillium lilacinum 1098.0 1098.0 1 * -3.1.8.1 parathion sulfolobus acidocaldarius 0.12 0.12 1 PMID:24894602 -3.1.8.1 pentafluorophenyl diethyl phosphate homo sapiens 678.0 339.3 2 PMID:15835926 -3.1.8.1 phenyl acetate homo sapiens 1236.0 1236.0 1 PMID:14695884 -3.1.8.1 phosmet purpureocillium lilacinum 771.0 771.0 1 * -3.1.8.1 resorcinol bis(diphenyl phosphate) sphingopyxis terrae subsp. terrae 4.87 4.87 1 PMID:36107214 -3.1.8.1 rp-o-ethyl methylphosphonyl-3-cyano-7-hydroxy-4-methylcoumarin synthetic construct 11.72 11.72 1 PMID:20303930 -3.1.8.1 rp-o-n-propyl methylphosphonyl-3-cyano-7-hydroxy-4-methylcoumarin synthetic construct 4.95 4.95 1 PMID:20303930 -3.1.8.1 s-(2-[di(propan-2-yl)amino]ethyl) o,o-diethyl phosphorothioate brevundimonas diminuta 1.1 1.1 1 PMID:30893549 -3.1.8.1 s-(2-[di(propan-2-yl)amino]ethyl) o,o-dimethyl phosphorothioate brevundimonas diminuta 0.021 0.021 1 PMID:30893549 -3.1.8.1 sarin homo sapiens 90.0 90.0 1 PMID:20701311 -3.1.8.1 soman homo sapiens 2.6 2.6 1 PMID:20701311 -3.1.8.1 sp-o-ethyl methylphosphonyl-3-cyano-7-hydroxy-4-methylcoumarin synthetic construct 0.15 0.15 1 PMID:20303930 -3.1.8.1 sp-o-n-propyl methylphosphonyl-3-cyano-7-hydroxy-4-methylcoumarin synthetic construct 1.83 1.83 1 PMID:20303930 -3.1.8.1 tricresyl phosphate sphingopyxis terrae subsp. terrae 7.21 7.21 1 PMID:36107214 -3.1.8.1 triphenyl phosphate sphingopyxis terrae subsp. terrae 276.0 276.0 1 PMID:36107214 -3.11.1.1 2-phosphonoacetaldehyde bacillus cereus 16.7 16.7 1 PMID:4989158 -3.11.1.1 phosphonoacetaldehyde achromobacter aegrifaciens 0.11 0.11 1 * -3.11.1.1 phosphonoacetaldehyde achromobacter insolitus 0.6 0.6 1 * -3.11.1.1 phosphonoacetaldehyde bacillus cereus 15.0 7.625 2 PMID:12416981;PMID:15005616;PMID:15109258 -3.11.1.2 phosphonoacetate penicillium oxalicum 1.7 1.7 1 PMID:16129582 -3.11.1.2 phosphonoacetate pseudomonas fluorescens 3.0 3.0 1 PMID:8529644 -3.11.1.2 phosphonoacetate sinorhizobium meliloti 1.1 1.0 2 PMID:21543322 -3.11.1.3 3-phosphonopyruvate variovorax sp. 105.0 105.0 1 PMID:16981709 -3.13.1.1 udp-glucose arabidopsis sp. 0.1 0.1 1 PMID:11073956 -3.13.1.1 udp-glucose arabidopsis thaliana 0.00167 0.00167 1 PMID:11073956 -3.13.1.4 3-sulfinopropanoyl-coa advenella mimigardefordensis 3.13 3.13 1 PMID:26057676 -3.13.1.4 3-sulfinopropionyl-coa advenella mimigardefordensis 3.13 3.115 2 PMID:23354747;PMID:24317404 -3.13.1.4 3-sulfinopropionyl-coa cupriavidus necator 4.4 4.4 1 PMID:24317404 -3.13.1.4 3-sulfinopropionyl-coa paraburkholderia xenovorans 1.1 1.1 1 PMID:24317404 -3.13.1.4 3-sulfinopropionyl-coa variovorax paradoxus 2.5 2.5 1 PMID:24317404 -3.13.1.5 carbon disulfide acidianus sp. 952.0 72.0 3 PMID:22012399 -3.13.1.5 carbonyl sulfide acidianus sp. 1800.0 1800.0 1 PMID:22012399 -3.13.1.7 carbonyl sulfide thiobacillus thioparus 58.0 58.0 1 PMID:23406161 -3.13.1.9 inosine methanocaldococcus jannaschii 0.83 0.83 1 PMID:25917907 -3.13.1.9 l-homocysteine methanocaldococcus jannaschii 0.83 0.83 1 PMID:25917907 -3.13.1.9 s-inosyl-l-homocysteine methanocaldococcus jannaschii 0.42 0.42 1 PMID:25917907 -3.13.2.1 adenosine homo sapiens 6666.0 6666.0 1 PMID:11134963 -3.13.2.1 adenosine lupinus luteus 4.3 4.3 1 PMID:21137580 -3.13.2.1 adenosine plasmodium falciparum 312.0 312.0 1 PMID:11134963 -3.13.2.1 adenosine trypanosoma cruzi 3.0 3.0 1 PMID:14969692 -3.13.2.1 cysteine lupinus luteus 0.11 0.11 1 PMID:21137580 -3.13.2.1 dl-homocysteine homo sapiens 6666.0 6666.0 1 PMID:11134963 -3.13.2.1 dl-homocysteine plasmodium falciparum 312.0 312.0 1 PMID:11134963 -3.13.2.1 dl-homocysteine trypanosoma cruzi 3.0 3.0 1 PMID:14969692 -3.13.2.1 s-adenosyl-dl-homocysteine cryptosporidium parvum 0.69 0.69 1 PMID:17559404 -3.13.2.1 s-adenosyl-dl-homocysteine homo sapiens 1908.0 955.725 2 PMID:11134963;PMID:15645450 -3.13.2.1 s-adenosyl-dl-homocysteine plasmodium falciparum 84.0 84.0 1 PMID:11134963 -3.13.2.1 s-adenosyl-dl-homocysteine pyrococcus furiosus 0.058 0.058 1 PMID:15645450 -3.13.2.1 s-adenosyl-dl-homocysteine rattus norvegicus 1.4 1.4 1 PMID:17214973 -3.13.2.1 s-adenosyl-dl-homocysteine trypanosoma cruzi 1.0 1.0 1 PMID:14969692 -3.13.2.1 s-adenosyl-l-homocysteine cytophaga hutchinsonii 0.042 0.042 2 * -3.13.2.1 s-adenosyl-l-homocysteine homo sapiens 0.79 0.79 1 PMID:25248746 -3.13.2.1 s-adenosyl-l-homocysteine pseudomonas aeruginosa 575.0 133.0 6 PMID:30054521 -3.13.2.1 s-adenosyl-l-homocysteine synechocystis sp. pcc 6803 0.192 0.186 5 PMID:35775986 -3.13.2.3 (r)-s-adenosyl-l-methionine salinispora tropica 0.0045 0.0045 1 PMID:32776704 -3.13.2.3 5'-chloro-5'-deoxyadenosine pyrococcus horikoshii 0.0052 0.0052 1 * -3.13.2.3 s-adenosyl-l-methionine pyrococcus horikoshii 0.14 0.14 1 * -3.13.2.3 s-adenosyl-l-methionine salinispora arenicola 0.0077 0.0076 2 PMID:18720493;PMID:19739191 -3.2.1.1 2-chloro-4-nitrophenyl alpha-d-maltoheptaoside hordeum vulgare 132.0 132.0 1 PMID:16403494 -3.2.1.1 2-chloro-4-nitrophenyl alpha-d-maltotrioside homo sapiens 2.98 2.98 1 PMID:15736945 -3.2.1.1 2-chloro-4-nitrophenyl alpha-maltotrioside homo sapiens 15.8 2.3 8 PMID:18284212 -3.2.1.1 2-chloro-4-nitrophenyl beta-d-glucopyranosyl-(1-4)-beta-d-glucopyranosyl-(1-4)-beta-d-glucopyranosyl-(1-4)-beta-d-glucopyranosyl-(1-4)-beta-d-glucopyranosyl-(1-4)-beta-d-glucopyranosyl-(1-4)-beta-d-glucopyranoside hordeum vulgare 6.0 6.0 1 PMID:18588886 -3.2.1.1 2-chloro-4-nitrophenyl beta-d-maltoheptaoside hordeum vulgare 119.0 57.55 4 PMID:14660599;PMID:17803687;PMID:9615479 -3.2.1.1 4,6-ethylidene-[g7]-p-nitrophenyl-[g1]-alpha-d-maltoheptaoside bacillus licheniformis 205.0 104.5 4 PMID:18626642 -3.2.1.1 4,6-ethylidene-[g7]-p-nitrophenyl-[g1]-alpha-d-maltoheptaoside hordeum vulgare 120.0 120.0 1 PMID:11890202 -3.2.1.1 4-nitrophenyl alpha-d-maltoheptaoside-4,6-o-ethylidene drosophila melanogaster 364.0 364.0 1 PMID:22634328 -3.2.1.1 4-nitrophenyl alpha-d-maltoheptaoside-4,6-o-ethylidene pseudoalteromonas haloplanktis 697.0 675.0 3 PMID:14499602;PMID:22634328 -3.2.1.1 4-nitrophenyl alpha-d-maltoheptaoside-4,6-o-ethylidene sus scrofa 291.0 291.0 3 PMID:14499602;PMID:22634328 -3.2.1.1 4-nitrophenyl alpha-d-maltoheptaoside-4,6-o-ethylidene thermobifida fusca 153.0 153.0 1 PMID:22634328 -3.2.1.1 4-nitrophenyl alpha-d-maltohexaoside thermotoga neapolitana 34.0 34.0 1 PMID:19834705 -3.2.1.1 4-nitrophenyl-alpha-d-maltoside sus scrofa 0.0497 0.04955 2 PMID:19807164 -3.2.1.1 acarbose pyrococcus furiosus 228.0 228.0 1 PMID:15466542 -3.2.1.1 alpha-cyclodextrin hyphopichia burtonii 0.399 0.399 1 PMID:18071262 -3.2.1.1 alpha-cyclodextrin moesziomyces antarcticus 10.7 10.7 1 PMID:3106037 -3.2.1.1 alpha-cyclodextrin pyrococcus furiosus 241.0 241.0 1 PMID:15466542 -3.2.1.1 alpha-maltosyl fluoride homo sapiens 443.0 443.0 1 PMID:11914097 -3.2.1.1 alpha-maltotriosyl fluoride homo sapiens 285.0 284.0 2 PMID:11914097;PMID:15736945 -3.2.1.1 amylopectin bifidobacterium longum 3.4 3.4 1 PMID:26979859 -3.2.1.1 amylopectin callosobruchus chinensis 1.1 1.1 1 PMID:27132147 -3.2.1.1 amylopectin corallococcus sp. egb 2274.8 2274.8 1 PMID:29752267 -3.2.1.1 amylopectin helicoverpa armigera 0.29 0.21 2 PMID:25907330 -3.2.1.1 amylopectin moesziomyces antarcticus 171.0 171.0 1 PMID:3106037 -3.2.1.1 amylopectin pyrococcus sp. 4180.0 4180.0 1 * -3.2.1.1 amylopectin ruminococcus bromii 137.0 137.0 2 PMID:30836186 -3.2.1.1 amylopectin tribolium castaneum 1.4 1.4 1 PMID:27132147 -3.2.1.1 amylopectin uncultured organism 0.15 0.096 2 PMID:25038927 -3.2.1.1 amylose bifidobacterium longum 116.1 116.1 1 PMID:26979859 -3.2.1.1 amylose hordeum vulgare 206.0 185.0 5 PMID:14511369;PMID:18588886;PMID:9615479 -3.2.1.1 amylose moesziomyces antarcticus 230.0 230.0 1 PMID:3106037 -3.2.1.1 amylose paenibacillus sp. ssg-1 9.21 9.21 1 PMID:27108054 -3.2.1.1 amylose pyrococcus sp. 2280.0 2280.0 1 * -3.2.1.1 amylose ruminococcus bromii 1014.0 1014.0 2 PMID:30836186 -3.2.1.1 amylose vigna angularis 71.8 63.65 2 PMID:12834286 -3.2.1.1 amylose dp17 hordeum vulgare 225.0 195.0 2 PMID:14660599;PMID:16403494 -3.2.1.1 amylose dp440 hordeum vulgare 209.0 197.0 2 PMID:16403494;PMID:17803687 -3.2.1.1 beta-cyclodextrin fusicoccum sp. 485.0 384.15 2 PMID:17690465 -3.2.1.1 beta-cyclodextrin hyphopichia burtonii 31.1 31.1 1 PMID:18071262 -3.2.1.1 beta-cyclodextrin moesziomyces antarcticus 29.4 29.4 1 PMID:3106037 -3.2.1.1 beta-cyclodextrin pyrococcus furiosus 196.0 196.0 1 PMID:15466542 -3.2.1.1 dextrin anabaena sp. 1940.0 1940.0 1 PMID:19756583 -3.2.1.1 gamma-cyclodextrin hyphopichia burtonii 64.6 64.6 1 PMID:18071262 -3.2.1.1 gamma-cyclodextrin moesziomyces antarcticus 186.0 186.0 1 PMID:3106037 -3.2.1.1 gamma-cyclodextrin pyrococcus furiosus 173.0 173.0 1 PMID:15466542 -3.2.1.1 glycogen moesziomyces antarcticus 166.0 148.0 2 PMID:3106037 -3.2.1.1 glycogen pyrococcus sp. 2300.0 2300.0 1 * -3.2.1.1 maltodextrin hordeum vulgare 129.0 127.0 2 PMID:14511369 -3.2.1.1 maltoheptaose hordeum vulgare 5.6 3.8 2 PMID:14511369 -3.2.1.1 maltoheptaose moesziomyces antarcticus 105.0 105.0 1 PMID:3106037 -3.2.1.1 maltoheptaose paenibacillus sp. ssg-1 573.8 573.8 1 PMID:27108054 -3.2.1.1 maltoheptaose struthio camelus 679.0 679.0 1 * -3.2.1.1 maltoheptaose thermotoga neapolitana 25.0 25.0 1 PMID:19834705 -3.2.1.1 maltohexaose hyphopichia burtonii 44.2 44.2 1 PMID:18071262 -3.2.1.1 maltohexaose struthio camelus 580.0 580.0 1 * -3.2.1.1 maltopentaose hyphopichia burtonii 37.2 37.2 1 PMID:18071262 -3.2.1.1 maltopentaose moesziomyces antarcticus 94.7 94.7 1 PMID:3106037 -3.2.1.1 maltopentaose paenibacillus sp. ssg-1 567.01 567.01 1 PMID:27108054 -3.2.1.1 maltopentaose struthio camelus 754.0 754.0 1 * -3.2.1.1 maltopentaose thermotoga neapolitana 283.0 283.0 1 PMID:19834705 -3.2.1.1 maltose hyphopichia burtonii 0.0258 0.0258 1 PMID:18071262 -3.2.1.1 maltose paenibacillus sp. ssg-1 428.98 428.98 1 PMID:27108054 -3.2.1.1 maltose struthio camelus 0.23 0.23 1 * -3.2.1.1 maltosyl fluoride homo sapiens 150.0 150.0 1 PMID:15736945 -3.2.1.1 maltotetraose hyphopichia burtonii 5.87 5.87 1 PMID:18071262 -3.2.1.1 maltotetraose struthio camelus 144.0 144.0 1 * -3.2.1.1 maltotriose hyphopichia burtonii 0.24 0.24 1 PMID:18071262 -3.2.1.1 maltotriose moesziomyces antarcticus 1.6 1.6 1 PMID:3106037 -3.2.1.1 maltotriose paenibacillus sp. ssg-1 538.95 538.95 1 PMID:27108054 -3.2.1.1 maltotriose pyrococcus furiosus 268.0 268.0 1 PMID:15466542 -3.2.1.1 maltotriose struthio camelus 0.81 0.81 1 * -3.2.1.1 maltotriose thermotoga neapolitana 809.0 809.0 1 PMID:19834705 -3.2.1.1 oyster glycogen anabaena sp. 750.0 750.0 1 PMID:19756583 -3.2.1.1 p-nitrophenylhexa[alpha-d-glucopyranosyl(1-4)]-alpha-d-glucopyranoside homo sapiens 175.0 175.0 1 PMID:14678792 -3.2.1.1 p-nitrophenylhexa[alpha-d-glucopyranosyl(1-4)]-alpha-d-glucopyranoside vigna angularis 85.3 73.85 2 PMID:12834286 -3.2.1.1 pullulan hyphopichia burtonii 0.085 0.085 1 PMID:18071262 -3.2.1.1 pullulan ruminococcus bromii 297.0 297.0 2 PMID:30836186 -3.2.1.1 pullulan thermoactinomyces vulgaris 140.0 140.0 1 PMID:15182368 -3.2.1.1 rabbit glycogen anabaena sp. 1920.0 1920.0 1 PMID:19756583 -3.2.1.1 raw starch geobacillus thermoleovorans 40000.0 40000.0 1 PMID:28382032 -3.2.1.1 raw starch heyndrickxia acidicola 40000.0 40000.0 1 PMID:28382032 -3.2.1.1 soluble potato starch anabaena sp. 3420.0 3420.0 1 PMID:19756583 -3.2.1.1 soluble potato starch tepidimonas fonticaldi 5.9 5.9 1 PMID:30928371 -3.2.1.1 soluble starch bacillus amyloliquefaciens 20.04 20.04 1 PMID:36857902 -3.2.1.1 soluble starch bacillus sp. dsh19-1 933.5 933.5 1 PMID:29936543 -3.2.1.1 soluble starch fusicoccum sp. 561.7 280.8625 2 PMID:17690465 -3.2.1.1 soluble starch geobacillus thermoleovorans 98.3 98.3 1 PMID:18025579 -3.2.1.1 soluble starch paenibacillus sp. ssg-1 0.72 0.72 1 PMID:27108054 -3.2.1.1 soluble starch pseudoalteromonas haloplanktis 0.128 0.128 1 PMID:31622706 -3.2.1.1 soluble starch ruminococcus bromii 1055.0 1055.0 1 PMID:30836186 -3.2.1.1 soluble starch thermotoga neapolitana 0.02 0.02 1 PMID:19834705 -3.2.1.1 starch bacillus sp. (in: firmicutes) 168.5 168.5 1 PMID:12856195 -3.2.1.1 starch callosobruchus chinensis 0.92 0.92 1 PMID:27132147 -3.2.1.1 starch corallococcus sp. egb 3021.2 3021.2 1 PMID:29752267 -3.2.1.1 starch drosophila melanogaster 280.0 280.0 1 PMID:22634328 -3.2.1.1 starch euplotes focardii 1466.0 982.0 3 PMID:23916704 -3.2.1.1 starch helicoverpa armigera 0.67 0.43000000000000005 2 PMID:25907330 -3.2.1.1 starch hyphopichia burtonii 91.4 91.4 1 PMID:18071262 -3.2.1.1 starch moesziomyces antarcticus 237.0 221.5 2 PMID:3106037 -3.2.1.1 starch moneuplotes crassus 880.0 619.0 3 PMID:23916704 -3.2.1.1 starch priestia megaterium 25.7 22.799999999999997 2 PMID:20177823 -3.2.1.1 starch pseudoalteromonas haloplanktis 179.0 179.0 1 PMID:22634328 -3.2.1.1 starch pyrococcus furiosus 67.0 67.0 1 PMID:15466542 -3.2.1.1 starch pyrococcus sp. 4680.0 4680.0 1 * -3.2.1.1 starch ruminococcus bromii 1055.0 1055.0 1 PMID:30836186 -3.2.1.1 starch streptomyces megasporus 3000.0 3000.0 1 PMID:10650713 -3.2.1.1 starch sus scrofa 518.0 0.035 5 PMID:22634328;PMID:23376024 -3.2.1.1 starch thermoactinomyces vulgaris 120.0 120.0 1 PMID:15182368 -3.2.1.1 starch thermobifida fusca 1457.0 1457.0 1 PMID:22634328 -3.2.1.1 starch tribolium castaneum 1.13 1.13 1 PMID:27132147 -3.2.1.1 starch uncultured organism 0.156 0.093 2 PMID:25038927 -3.2.1.1 starch zunongwangia profunda 1449.43 1449.43 1 PMID:26657843 -3.2.1.10 4-nitrophenyl alpha-d-glucopyranoside arthrobacter globiformis 697.0 697.0 1 * -3.2.1.10 4-nitrophenyl alpha-d-glucopyranoside bacillus cereus 483.0 483.0 1 PMID:11676021 -3.2.1.10 4-nitrophenyl alpha-d-glucopyranoside exiguobacterium artemiae 260.0 260.0 1 PMID:34439895 -3.2.1.10 4-nitrophenyl alpha-d-glucopyranoside homo sapiens 17.0 17.0 1 PMID:20356844 -3.2.1.10 4-nitrophenyl alpha-d-glucopyranoside saccharomyces cerevisiae 129.0 14.0 5 PMID:11856334;PMID:24649402 -3.2.1.10 isomaltose arthrobacter globiformis 41.0 41.0 1 * -3.2.1.10 isomaltose bifidobacterium breve 36.3 33.55 2 PMID:19114534 -3.2.1.10 isomaltose homo sapiens 97.0 97.0 1 PMID:20356844 -3.2.1.10 isomaltose saccharomyces cerevisiae 103.0 97.0 5 PMID:11856334;PMID:24649402 -3.2.1.10 isomaltotriose bifidobacterium breve 12.5 12.25 2 PMID:19114534 -3.2.1.10 isomaltriose saccharomyces cerevisiae 21.0 18.0 3 PMID:24649402 -3.2.1.10 maltose homo sapiens 137.0 137.0 1 PMID:20356844 -3.2.1.10 methyl alpha-d-glucopyranoside saccharomyces cerevisiae 88.0 84.0 3 PMID:24649402 -3.2.1.10 palatinose bifidobacterium breve 13.0 12.7 2 PMID:19114534 -3.2.1.10 palatinose saccharomyces cerevisiae 104.0 67.0 4 PMID:24649402 -3.2.1.10 panose bifidobacterium breve 30.0 29.35 2 PMID:19114534 -3.2.1.10 sucrose anoxybacillus gonensis 6.7 6.7 2 PMID:37378888 -3.2.1.10 sucrose saccharomyces cerevisiae 55.0 38.0 4 PMID:24649402 -3.2.1.10 trehalose bifidobacterium breve 7.3 6.55 2 PMID:19114534 -3.2.1.10 trehalulose bifidobacterium breve 38.7 37.05 2 PMID:19114534 -3.2.1.100 beta-mannan xanthomonas citri 12.53 12.53 1 PMID:29997257 -3.2.1.100 mannohexaose xanthomonas citri 126.86 126.86 1 PMID:29997257 -3.2.1.101 alpha-1,6-d-mannan niallia circulans 7.33 7.33 1 PMID:811665 -3.2.1.102 2,4-dinitrophenyl 2-acetamido-2-deoxy-d-galactopyranosyl-(1,3)-[alpha-l-fucopyranosyl-(1,2)]-beta-d-galactopyranoside clostridium perfringens 1.75 1.75 1 PMID:19630404 -3.2.1.102 blood group a glycoconjugate streptococcus pneumoniae 4.67 4.67 1 PMID:19608744 -3.2.1.102 blood group a ii tetrasaccharide mediterraneibacter gnavus 0.0028 0.0028 1 PMID:34936658 -3.2.1.102 blood group b glycoconjugate streptococcus pneumoniae 11.17 11.17 1 PMID:19608744 -3.2.1.104 (6-[n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]hexanoyl)-beta-d-glucosylceramide cryptococcus neoformans 0.53 0.53 1 PMID:25361768 -3.2.1.104 4-methylumbelliferyl beta-d-glucoside cryptococcus neoformans 8.8 8.8 1 PMID:25361768 -3.2.1.104 4-nitrophenyl beta-d-glucoside cryptococcus neoformans 13.8 13.8 1 PMID:25361768 -3.2.1.104 resorufin 3-o-beta-d-glucoside cryptococcus neoformans 21.9 21.9 1 PMID:25361768 -3.2.1.106 glc3man9glcnac2-pyridylamine aspergillus brasiliensis 1450.0 1450.0 1 PMID:22020441 -3.2.1.106 glcalpha(1->2)glcalpha(1->3)glcalpha(1->3)manalpha(1->2)manalpha(1->2)manalpha(1->3)manbeta(1->4)glcnacbeta(1->4)glcnacbeta-pyridylamine aspergillus brasiliensis 1100.0 1100.0 1 PMID:22020441 -3.2.1.108 daidzein-7-glucoside ovis aries 2.1 2.1 1 PMID:10692580 -3.2.1.108 genistein-7-glucoside ovis aries 6.5 6.5 1 PMID:10692580 -3.2.1.108 lactose ovis aries 33.8 33.8 1 PMID:10692580 -3.2.1.108 phlorizin ovis aries 0.5 0.5 1 PMID:10692580 -3.2.1.108 quercetin-3-glucoside ovis aries 6.3 6.3 1 PMID:10692580 -3.2.1.108 quercetin-4'-glucoside ovis aries 7.5 7.5 1 PMID:10692580 -3.2.1.11 dextran chaetomium erraticum 4564.0 364.85 8 * -3.2.1.11 dextran pseudarthrobacter oxydans 12.6 12.6 1 PMID:36656394 -3.2.1.11 dextran streptococcus mutans 77.0 77.0 1 PMID:29806555 -3.2.1.11 dextran talaromyces aculeatus 2230.0 1495.0 4 PMID:18264680;PMID:18307270 -3.2.1.11 dextran 742cb thermoanaerobacter pseudethanolicus 3.7 3.7 1 PMID:22561857 -3.2.1.11 dextran t10 cellulosimicrobium sp. thn1 43.026 43.026 1 PMID:36439846 -3.2.1.11 dextran t100 talaromyces pinophilus 4872.0 4872.0 1 PMID:28013394 -3.2.1.11 dextran t20 cellulosimicrobium sp. thn1 55.039 55.039 1 PMID:36439846 -3.2.1.11 dextran t2000 paenibacillus sp. 44.3 44.3 1 PMID:22461618 -3.2.1.11 dextran t2000 penicillium cyclopium 809.14 516.335 2 PMID:30889875;PMID:35124020 -3.2.1.11 dextran t2000 thermoanaerobacter pseudethanolicus 10.2 10.2 1 PMID:22561857 -3.2.1.11 dextran t40 talaromyces pinophilus 163.0 163.0 1 PMID:28013394 -3.2.1.11 dextran t5 penicillium cyclopium 777.03 492.74 2 PMID:30889875;PMID:35124020 -3.2.1.11 dextran t500 thermoanaerobacter pseudethanolicus 8.1 8.1 1 PMID:22561857 -3.2.1.11 dextran t70 cellulosimicrobium sp. thn1 37.488 37.488 1 PMID:36439846 -3.2.1.11 dextran t70 penicillium cyclopium 800.58 506.27500000000003 2 PMID:30889875;PMID:35124020 -3.2.1.11 dextran t70 pseudarthrobacter oxydans 206.0 206.0 1 PMID:31430863 -3.2.1.11 dextran t70 streptococcus mutans 79.0 79.0 1 PMID:36343755 -3.2.1.11 dextran t70 talaromyces pinophilus 369.0 369.0 1 PMID:28013394 -3.2.1.11 isomaltoheptaose paenibacillus sp. 7.93 7.93 1 PMID:22461618 -3.2.1.11 isomaltohexaose paenibacillus sp. 7.53 7.53 1 PMID:22461618 -3.2.1.11 isomaltopentaose paenibacillus sp. 4.36 4.36 1 PMID:22461618 -3.2.1.111 2-chloro-4-nitrophenyl-alpha-l-fucopyranoside uncultured bacterium 31.0 31.0 1 PMID:35137077 -3.2.1.111 3-fucosyllactose elizabethkingia meningoseptica 4.12 4.12 1 PMID:29196602 -3.2.1.111 4-nitrophenyl alpha-l-fucoside elizabethkingia meningoseptica 0.14 0.14 1 PMID:29196602 -3.2.1.111 fuc-alpha-(1-4)-glcnac uncultured bacterium 1.3 1.3 1 PMID:35137077 -3.2.1.111 lewis x trisaccharide elizabethkingia meningoseptica 21.55 21.55 1 PMID:29196602 -3.2.1.113 manalpha(1,2)man-o-me aspergillus phoenicis 8.51 8.51 1 PMID:16306691 -3.2.1.114 2,4-dinitrophenyl alpha-d-mannoside drosophila melanogaster 8.6 8.6 1 PMID:12960159 -3.2.1.114 3-o-alpha-d-mannopyranosyl-alpha-d-mannopyranose homo sapiens 4.67 4.67 1 PMID:20081828 -3.2.1.114 3-o-alpha-d-mannopyranosyl-alpha-d-mannopyranose streptococcus pyogenes m1 gas 6.4 6.4 1 PMID:20140249 -3.2.1.114 4-methylumbelliferyl alpha-d-mannopyranoside streptococcus pyogenes m1 gas 0.03 0.03 1 PMID:20140249 -3.2.1.114 4-nitrophenyl alpha-d-mannopyranoside homo sapiens 0.0025 0.0025 1 PMID:20081828 -3.2.1.114 5-fluoro-beta-l-gulosyl fluoride drosophila melanogaster 0.0051 0.0051 1 PMID:12960159 -3.2.1.116 amylopectin microbacterium imperiale 19.4 19.4 1 * -3.2.1.116 amylose kitasatospora sp. mk-1785 53.8 53.8 1 PMID:25620369 -3.2.1.116 beta-dextrin-1 microbacterium imperiale 26.5 26.5 1 * -3.2.1.116 beta-dextrin-2 microbacterium imperiale 33.0 33.0 1 * -3.2.1.116 beta-dextrin-3 microbacterium imperiale 37.2 37.2 1 * -3.2.1.116 maltopentaose kitasatospora sp. mk-1785 58.1 58.1 1 PMID:25620369 -3.2.1.116 maltotetraose kitasatospora sp. mk-1785 14.7 14.7 1 PMID:25620369 -3.2.1.120 alpha-d-xyl-(1->6)-beta-d-glc aspergillus oryzae 532.0 532.0 1 PMID:26755723 -3.2.1.120 alpha-d-xyl-(1->6)-beta-d-glc-(1->4)-[alpha-d-xyl-(1->6)]-beta-d-glc-(1->4)-beta-d-glc aspergillus oryzae 1216.0 1216.0 1 PMID:26755723 -3.2.1.120 alpha-d-xyl-(1->6)-beta-d-glc-(1->4)-[beta-d-gal-(1->2)-alpha-d-xyl-(1->6)]-beta-d-glc-(1->4)-[beta-d-gal-(1->2)-alpha-d-xyl-(1->6)]-beta-d-glc aspergillus oryzae 661.0 661.0 1 PMID:26755723 -3.2.1.120 glc4xyl3 aspergillus oryzae 753.0 753.0 1 PMID:35717558 -3.2.1.122 3,4-dinitrophenyl 6-phospho-alpha-d-glucoside bacillus subtilis 0.81 0.765 2 PMID:17676871 -3.2.1.122 4-nitrophenyl 6-phospho-alpha-d-glucoside bacillus subtilis 0.85 0.7749999999999999 2 PMID:17676871 -3.2.1.122 maltose 6'-phosphate bacillus subtilis 1.3 1.3 2 PMID:17676871 -3.2.1.122 maltose 6'-phosphate enterococcus faecalis 128.0 128.0 1 PMID:23490043 -3.2.1.122 methyl 6-phospho-alpha-d-glucoside bacillus subtilis 1.1 0.76 2 PMID:17676871 -3.2.1.122 phenyl 6-phospho-alpha-d-glucoside bacillus subtilis 0.9 0.5800000000000001 2 PMID:17676871 -3.2.1.123 4-methylumbelliferyl beta-d-glucoside cryptococcus neoformans 8.8 8.8 1 PMID:25361768 -3.2.1.123 4-nitrophenyl beta-d-galactopyranoside prescottella equi 0.00665 0.00665 1 PMID:31557527 -3.2.1.123 4-nitrophenyl-beta-d-glucoside cryptococcus neoformans 13.8 13.8 1 PMID:25361768 -3.2.1.123 beta-d-gal-(1->3)-beta-d-galnac-(1->4)-(alpha-neu5ac-(2->3))-beta-d-gal-(1->4)-beta-d-glc-(1<->1')-ceramide prescottella equi 10.5 10.5 1 PMID:28179425 -3.2.1.123 beta-d-gal-(1->3)-beta-d-galnac-(1->4)-(alpha-neu5ac-(2->3))-beta-d-gal-(1->4)-beta-d-glc-(1<->1')-ceramide rhodococcus sp. m-777 0.088 0.088 1 PMID:28179425 -3.2.1.123 c6-7-nitro-2,1,3-benzoxadiazole-glucosylceramide cryptococcus neoformans 0.53 0.28415 2 PMID:25361768 -3.2.1.123 d-erythro-dihydrosphingosine rhodococcus sp. (in: high g+c gram-positive bacteria) 0.12 0.12 1 PMID:17329247 -3.2.1.123 d-erythro-sphingosine rhodococcus sp. (in: high g+c gram-positive bacteria) 0.07 0.07 1 PMID:17329247 -3.2.1.123 galbeta1-6galbeta1-6galbeta1-1'ceramide prescottella equi 13.3 13.3 1 PMID:17244618 -3.2.1.123 ganglioside gb3cer prescottella equi 85.0 42.5345 2 PMID:22798689 -3.2.1.123 ganglioside gm1a prescottella equi 120.0 62.85 2 PMID:22798689 -3.2.1.123 resorufin cryptococcus neoformans 21.9 21.9 1 PMID:25361768 -3.2.1.126 coniferin agrobacterium tumefaciens 106.0 106.0 1 PMID:9630531 -3.2.1.126 coniferin pyrus x bretschneideri 0.54 0.385 2 PMID:35620693 -3.2.1.126 o-nitrophenyl beta-d-glucopyranoside agrobacterium tumefaciens 155.0 155.0 1 PMID:9630531 -3.2.1.126 p-nitrophenyl alpha-l-arabinofuranoside agrobacterium tumefaciens 118.0 118.0 1 PMID:9630531 -3.2.1.126 p-nitrophenyl beta-d-fucopyranoside agrobacterium tumefaciens 22.1 22.1 1 PMID:9630531 -3.2.1.126 p-nitrophenyl beta-d-galactopyranoside agrobacterium tumefaciens 46.6 46.6 1 PMID:9630531 -3.2.1.126 p-nitrophenyl beta-d-glucopyranoside agrobacterium tumefaciens 95.4 49.300000000000004 2 PMID:9630531 -3.2.1.126 p-nitrophenyl beta-d-xylopyranoside agrobacterium tumefaciens 28.9 28.9 1 PMID:9630531 -3.2.1.126 salicin agrobacterium tumefaciens 86.7 44.925000000000004 2 PMID:9630531 -3.2.1.126 syringin pyrus x bretschneideri 0.36 0.28 2 PMID:35620693 -3.2.1.127 2'-fucosyllactose bifidobacterium longum subsp. infantis 2.4 2.4 1 PMID:34429696 -3.2.1.127 4-nitrophenyl alpha-l-fucopyranoside bacteroides fragilis 183.8 183.8 1 PMID:28103685 -3.2.1.127 4-nitrophenyl alpha-l-fucopyranoside bifidobacterium longum subsp. infantis 70.8 70.8 1 PMID:34429696 -3.2.1.127 4-nitrophenyl alpha-l-fucopyranoside bombyx mori 12.5 12.5 1 PMID:32561391 -3.2.1.127 fuc-alpha-1,2-gal bifidobacterium longum subsp. infantis 12.6 12.6 1 PMID:34429696 -3.2.1.127 fuc-alpha-1,6-glcnac bifidobacterium longum subsp. infantis 29.1 29.1 1 PMID:34429696 -3.2.1.129 polysialic acid vectrevirus k1e 1.5 1.1 6 PMID:11994155 -3.2.1.129 trifluoromethylumbelliferyl sialotrioside escherichia phage k1f 1.28 1.28 1 PMID:19411257 -3.2.1.130 4-methylumbelliferyl (alpha-d-glucopyranosyl)-(1->3)-alpha-d-mannopyranoside bacteroides xylanisolvens 7.17e-05 7.17e-05 1 PMID:25487964 -3.2.1.130 4-methylumbelliferyl (alpha-d-mannopyranosyl)-(1->3)-alpha-d-mannopyranoside bacteroides thetaiotaomicron 0.00115 0.00115 1 PMID:25487964 -3.2.1.130 4-methylumbelliferyl (alpha-d-mannopyranosyl)-(1->3)-alpha-d-mannopyranoside bacteroides xylanisolvens 8e-05 8e-05 1 PMID:25487964 -3.2.1.130 alpha-glucopyranosyl-(1->3)-alpha-mannopyranosyl fluoride bacteroides thetaiotaomicron 4.77 4.77 1 PMID:22219371 -3.2.1.130 alpha-glucopyranosyl-(1->3)-alpha-mannopyranosyl fluoride bacteroides xylanisolvens 6.34 6.34 1 PMID:22219371 -3.2.1.131 4-o-me-glca-alpha-(1->2)-xyl-beta(1->4)-xyl bacteroides ovatus 18.4 18.4 1 PMID:24214982 -3.2.1.131 4-o-methyl-alpha-d-glucopyranosyl uronic acid-(1->2)-[beta-d-xylopyranosyl-(1->4)]-beta-d-xylopyranosyl-(1->4)-d-xylose amphibacillus xylanus 29.2 29.2 1 PMID:28648176 -3.2.1.131 4-o-methyl-alpha-d-glucopyranosyl-(1->2)-[beta-d-xylopyranosyl-(1->4)]-beta-d-xylopyranosyl-(1->4)-beta-d-xylopyranosyl-(1->4)-d-xylopyranose amphibacillus xylanus 72.7 72.7 1 PMID:28648176 -3.2.1.131 4-o-methyl-beta-d-glucopyranuetaronosyl-(1->2)-b-d-xylopyranosyl-(1->4)-beta-d-xylopyranosyl-(1->4)-beta-d-xylopyranose pseudothermotoga thermarum 117.0 117.0 1 * -3.2.1.131 aldobiouronic acid cellvibrio japonicus 69.2 69.2 1 PMID:11937059 -3.2.1.131 aldopentaouronic acid cellvibrio japonicus 132.0 132.0 1 PMID:11937059 -3.2.1.131 aldotetraouronic acid cellvibrio japonicus 103.0 103.0 1 PMID:11937059 -3.2.1.131 aldotetraouronic acid geobacillus stearothermophilus 54.9 54.9 1 PMID:11358519 -3.2.1.131 aldotriouronic acid cellvibrio japonicus 96.0 96.0 1 PMID:11937059 -3.2.1.131 aldouronic acid paenibacillus curdlanolyticus 1082.0 1082.0 1 PMID:25765307 -3.2.1.131 aldouronic acid thermotoga maritima 62.4 62.4 1 PMID:36175749 -3.2.1.131 aldouronic acid uncultured bacterium 1.48 1.3900000000000001 2 PMID:35503213 -3.2.1.131 aldouronic acids pseudothermotoga thermarum 117.0 117.0 1 * -3.2.1.131 arabinoglucuronoxylan amphibacillus xylanus 487.3 487.3 1 PMID:28648176 -3.2.1.131 beechwood xylan bacteroides ovatus 11.6 11.6 1 PMID:24214982 -3.2.1.131 birchwood xylan bacteroides ovatus 11.1 11.1 1 PMID:24214982 -3.2.1.131 birchwood xylan saccharophagus degradans 289.0 289.0 1 PMID:27129264 -3.2.1.131 xyl-beta-(1->4)-[4-o-me-glca-alpha-(1->2)]-xyl-beta(1->4)-xyl bacteroides ovatus 53.9 53.9 1 PMID:24214982 -3.2.1.132 30% n-acetylated chitosan streptomyces sp. 71.4 45.1 5 PMID:9989221 -3.2.1.132 4-methylumbelliferyl beta-chitotrioside streptomyces sp. 8.1e-05 8.1e-05 1 PMID:10467161 -3.2.1.132 chitohexaose streptomyces sp. 107.0 107.0 1 PMID:10467161 -3.2.1.132 chitopentaose bacillus sp. mn 8.0 8.0 1 PMID:30918529 -3.2.1.132 chitosan aspergillus sp. w-2 0.47 0.47 1 PMID:26277746 -3.2.1.132 chitosan bacillus amyloliquefaciens 204.0 204.0 1 PMID:33393308 -3.2.1.132 chitosan bacillus sp. mn 23.0 23.0 1 PMID:30918529 -3.2.1.132 chitosan bacillus sp. ts 505000.0 505000.0 1 PMID:27318711 -3.2.1.132 chitosan bacillus subtilis 18142.0 10899.05 20 PMID:37705423 -3.2.1.132 chitosan gynuella sunshinyii 187.36 187.36 1 PMID:33080262 -3.2.1.132 chitosan microbacterium sp. 205.0 205.0 1 PMID:24766439 -3.2.1.132 chitosan paenibacillus ehimensis 2.5 2.5 1 PMID:27395063 -3.2.1.132 chitosan paenibacillus sp. 126.5 126.5 1 PMID:23076590 -3.2.1.132 chitosan renibacterium sp. qd1 72000.0 47250.0 4 PMID:28748352 -3.2.1.132 chitosan streptomyces hygroscopicus 3.45 3.45 1 PMID:35173697 -3.2.1.132 chitosan streptomyces sp. 11.2 10.35 4 PMID:24041306;PMID:24338856 -3.2.1.132 chitosan streptomyces sp. n174 12.4 12.4 1 PMID:19143844 -3.2.1.132 chitosan sus scrofa 6.2 5.9 3 PMID:12568570 -3.2.1.132 chitosan uncultured bacterium 0.68 0.68 1 PMID:32548690 -3.2.1.132 chitotetraose bacillus sp. mn 23.0 23.0 1 PMID:30918529 -3.2.1.133 acarbose thermus sp. 67.8 67.8 1 PMID:10841756 -3.2.1.133 alpha-cyclodextrin geobacillus sp. 500.0 500.0 1 PMID:23639697 -3.2.1.133 alpha-cyclodextrin geobacillus thermoleovorans 2.78 1.44 2 PMID:24069213 -3.2.1.133 alpha-cyclodextrin staphylothermus marinus 1.45 1.45 1 PMID:22223643 -3.2.1.133 amylopectin geobacillus sp. 15.38 15.38 1 PMID:23639697 -3.2.1.133 amylopectin geobacillus thermoleovorans 0.17 0.10500000000000001 2 PMID:24069213 -3.2.1.133 amylopectin staphylothermus marinus 0.8 0.8 1 PMID:22223643 -3.2.1.133 amylopectin thermofilum pendens 4.01 4.01 1 * -3.2.1.133 amylose geobacillus sp. 62.82 62.82 1 PMID:23639697 -3.2.1.133 amylose geobacillus thermoleovorans 0.21 0.125 2 PMID:24069213 -3.2.1.133 amylose staphylothermus marinus 0.59 0.59 1 PMID:22223643 -3.2.1.133 amylose thermofilum pendens 4.21 4.21 1 * -3.2.1.133 beta-cyclodextrin geobacillus sp. 280.8 280.8 1 PMID:23639697 -3.2.1.133 beta-cyclodextrin geobacillus thermoleovorans 1.33 0.7250000000000001 2 PMID:24069213 -3.2.1.133 beta-cyclodextrin lactiplantibacillus plantarum 87.9 87.9 1 * -3.2.1.133 beta-cyclodextrin shouchella lehensis 12.5 3.06 7 PMID:25221964;PMID:31759025;PMID:32035147 -3.2.1.133 beta-cyclodextrin staphylothermus marinus 5.36 5.36 1 PMID:22223643 -3.2.1.133 beta-cyclodextrin thermus sp. 200.0 145.0 10 PMID:11714271;PMID:12902281 -3.2.1.133 gamma-cyclodextrin geobacillus sp. 225.6 225.6 1 PMID:23639697 -3.2.1.133 gamma-cyclodextrin staphylothermus marinus 29.1 29.1 1 PMID:22223643 -3.2.1.133 maltoheptaose thermus sp. 384.1 213.3 2 PMID:15975859 -3.2.1.133 maltohexaose thermus sp. 160.3 84.75 2 PMID:15975859 -3.2.1.133 maltopentaose pyrococcus sp. 0.0017 0.0017 1 PMID:23884203 -3.2.1.133 maltopentaose thermococcus sp. 3.85 3.85 1 PMID:24835094 -3.2.1.133 maltopentaose thermus sp. 197.0 197.0 1 PMID:15975859 -3.2.1.133 maltose thermus sp. 0.29 0.29 1 PMID:15975859 -3.2.1.133 maltotetraose pyrococcus sp. 0.0033 0.0033 1 PMID:23884203 -3.2.1.133 maltotetraose thermococcus sp. 3.95 3.95 1 PMID:24835094 -3.2.1.133 maltotetraose thermus sp. 574.1 301.95 2 PMID:15975859 -3.2.1.133 maltotriose geobacillus stearothermophilus 137.2 137.2 1 PMID:26597712 -3.2.1.133 maltotriose pyrococcus sp. 6.35 6.35 1 PMID:23884203 -3.2.1.133 maltotriose thermococcus sp. 11.45 11.45 1 PMID:24835094 -3.2.1.133 maltotriose thermus sp. 652.5 652.5 1 PMID:15975859 -3.2.1.133 soluble starch geobacillus thermoleovorans 0.2 0.12000000000000001 2 PMID:24069213 -3.2.1.133 soluble starch lactiplantibacillus plantarum 171.7 171.7 1 * -3.2.1.133 soluble starch shouchella lehensis 9.9 0.0243 3 PMID:25221964 -3.2.1.133 starch thermus sp. 457.0 301.0 3 PMID:11714271;PMID:11923309 -3.2.1.135 pullulan geobacillus stearothermophilus 62000.0 62000.0 1 * -3.2.1.135 pullulan ruminococcus bromii 297.0 297.0 1 PMID:30836186 -3.2.1.135 pullulan thermoanaerobacter ethanolicus 1010.0 919.15 2 PMID:18500431 -3.2.1.135 soluble starch geobacillus stearothermophilus 111000.0 111000.0 1 * -3.2.1.135 starch thermoanaerobacter ethanolicus 313.3 305.8 2 PMID:18500431 -3.2.1.136 4-o-methyl-d-glucuronoxylan dickeya chrysanthemi 34.1 34.1 1 PMID:29477770 -3.2.1.136 4-o-methyl-d-glucuronoxylan methyl ester dickeya chrysanthemi 0.27 0.27 1 PMID:29477770 -3.2.1.136 4-o-methylglucoxylan dickeya chrysanthemi 0.15 0.15 1 PMID:29477770 -3.2.1.139 4-nitrophenyl-2-o-(4-o-methyl-alpha-d-glucuronosyl)-beta-d-xylopyranoside cellvibrio japonicus 143.0 143.0 1 PMID:12654910 -3.2.1.139 4-o-methyl-beta-d-glucopyranuetaronosyl-(1->2)-b-d-xylopyranosyl-(1->4)-beta-d-xylopyranosyl-(1->4)-beta-d-xylopyranose paenibacillus curdlanolyticus 1082.0 1082.0 1 PMID:25765307 -3.2.1.139 aldobiouronic acid cellvibrio japonicus 69.2 69.2 1 PMID:11937059 -3.2.1.139 aldopentaouronic acid cellvibrio japonicus 131.9 131.9 1 PMID:11937059 -3.2.1.139 aldopentaouronic acid scheffersomyces stipitis 51.1 51.1 1 * -3.2.1.139 aldotetraouronic acid cellvibrio japonicus 102.5 102.5 1 PMID:11937059 -3.2.1.139 aldotetraouronic acid geobacillus stearothermophilus 54.9 54.9 1 PMID:11358519 -3.2.1.139 aldotetraouronic acid scheffersomyces stipitis 69.2 69.2 1 * -3.2.1.139 aldotriouronic acid cellvibrio japonicus 96.0 96.0 1 PMID:11937059 -3.2.1.139 beechwood xylan bacteroides ovatus 13.95 12.774999999999999 2 PMID:24214982 -3.2.1.139 beechwood xylan scheffersomyces stipitis 24.2 24.2 1 * -3.2.1.139 birchwood xylan bacteroides ovatus 14.37 12.725 2 PMID:24214982 -3.2.1.139 birchwood xylan saccharophagus degradans 289.0 289.0 1 PMID:27129264 -3.2.1.139 birchwood xylan scheffersomyces stipitis 19.4 19.4 1 * -3.2.1.139 p-nitrophenyl alpha-d-glucuronopyranoside thermotoga maritima 0.28 0.28 1 PMID:14646194 -3.2.1.139 p-nitrophenyl-alpha-d-glucuronopyranoside thermotoga maritima 0.0018 0.0018 1 PMID:12062428 -3.2.1.14 4-methyl-2-oxo-2h-chromen-7-yl 2-(acetylamino)-4-o-[2-(acetylamino)-2-deoxy-beta-d-glucopyranosyl]-2-deoxy-beta-d-glucopyranoside bacillus cereus 0.9 0.9 1 * -3.2.1.14 4-methylumbelliferyl 2-acetamido-4-o-(2-acetamido-2,4-dideoxy-beta-d-xylo-hexopyranosyl)-2-deoxy-beta-d-glucopyranoside homo sapiens 0.713 0.34 3 PMID:19435888 -3.2.1.14 4-methylumbelliferyl beta-d-n,n',n''-triacetylchitotrioside bacillus thuringiensis 4.98 4.98 1 PMID:28377239 -3.2.1.14 4-methylumbelliferyl beta-d-n,n'-diacetylchitobioside ostrinia furnacalis 1.78 0.665 4 PMID:29317504 -3.2.1.14 4-methylumbelliferyl beta-n,n',n''-triacetylchitotrioside ficus pumila var. awkeotsang 0.089 0.089 1 PMID:14634152 -3.2.1.14 4-methylumbelliferyl beta-n,n',n''-triacetylchitotrioside manduca sexta 0.76 0.27 7 PMID:12770581 -3.2.1.14 4-methylumbelliferyl chitobioside annona cherimola 2.87 2.87 1 PMID:20576315 -3.2.1.14 4-methylumbelliferyl chitobioside homo sapiens 3.0 3.0 1 PMID:20036323 -3.2.1.14 4-methylumbelliferyl chitobioside macaca fascicularis 31.8 31.8 1 PMID:20036323 -3.2.1.14 4-methylumbelliferyl chitotriose annona cherimola 6.93 6.93 1 PMID:20576315 -3.2.1.14 4-methylumbelliferyl glcnacbeta(1-4)glcnacbeta(1-4)glcnac aeromonas caviae 0.0007 0.0007 1 PMID:19089411 -3.2.1.14 4-methylumbelliferyl-beta-d-n,n',n''-triacetylchitotrioside serratia marcescens 67.4 56.8 3 PMID:18323665 -3.2.1.14 4-methylumbelliferyl-glcnacbeta(1->4)glcnac aeromonas caviae 0.006 0.006 1 PMID:19089411 -3.2.1.14 4-methylumbelliferyl-n,n',n''-triacetylchitotriose saccharomyces cerevisiae 1.3 1.3 1 PMID:17524989 -3.2.1.14 4-methylumbelliferyl-n,n',n''-triacetylchitotriose vibrio parahaemolyticus 110.6 65.8 2 PMID:17508209 -3.2.1.14 4-methylumbelliferyl-n,n'-diacetylchitobiose chromobacterium sp. 18.0 18.0 1 PMID:17294188 -3.2.1.14 4-methylumbelliferyl-n,n'-diacetylchitobiose vibrio parahaemolyticus 13.94 7.2299999999999995 2 PMID:17508209 -3.2.1.14 4-methylumbelliferyl-tri-n-acetylchitotriose niallia circulans 22.4 0.14 3 PMID:12930197 -3.2.1.14 4-nitrophenol-beta-d-cellobioside thermococcus chitonophagus 0.04 0.04 1 PMID:12579379 -3.2.1.14 4-nitrophenyl 2-(acetylamino)-4-o-[2-(acetylamino)-2-deoxy-beta-d-glucopyranosyl]-2-deoxy-beta-d-glucopyranoside trichoderma harzianum 0.35 0.3085 2 PMID:16997574 -3.2.1.14 4-nitrophenyl beta-d-n,n',n''-triacetylchitotrioside trichoderma harzianum 0.107 0.107 1 PMID:27456116 -3.2.1.14 4-nitrophenyl beta-n,n'-diacetylchitobioside bacillus licheniformis 0.43 0.31 5 PMID:19370717;PMID:20133129 -3.2.1.14 4-nitrophenyl beta-n,n'-diacetylchitobioside pyrococcus furiosus 6.7 6.7 1 PMID:20553502 -3.2.1.14 4-nitrophenyl n,n',n'',n'''-tetraacetylchitotetraoside paenibacillus timonensis 272270.0 272270.0 1 PMID:31349143 -3.2.1.14 4-nitrophenyl n,n',n''-beta-d-triacetylchitotrioside coprinopsis cinerea 1.13 1.13 1 PMID:28721730 -3.2.1.14 4-nitrophenyl n,n'-diacetyl-beta-d-chitobioside coprinopsis cinerea 2.28 2.28 1 PMID:28721730 -3.2.1.14 4-nitrophenyl n,n'-diacetyl-beta-d-chitobioside listeria innocua 51.1 30.75 2 PMID:27138200 -3.2.1.14 4-nitrophenyl n,n'-diacetyl-beta-d-chitobioside paenibacillus thermoaerophilus 9.6 9.6 1 PMID:25304023 -3.2.1.14 4-nitrophenyl n,n'-diacetylchitobiose paenibacillus sp. 0.99 0.99 1 PMID:25036959 -3.2.1.14 4-nitrophenyl n-acetyl-d-glucosaminide euphorbia characias 34.0 34.0 1 PMID:26318237 -3.2.1.14 4-nitrophenyl-beta-1,4-n,n'-diacetyl-chitobiose moritella marina 19.54 6.395 6 PMID:18368288 -3.2.1.14 beta-chitin serratia marcescens 13.9 5.699999999999999 6 PMID:25812992 -3.2.1.14 carboxymethyl chitin niallia circulans 25.2 24.1 3 PMID:12930197 -3.2.1.14 cellulose thermococcus chitonophagus 0.003 0.003 1 PMID:12579379 -3.2.1.14 chitin paenibacillus sp. 83.46 83.46 1 PMID:21049291 -3.2.1.14 chitin thermococcus chitonophagus 0.005 0.005 1 PMID:12579379 -3.2.1.14 chitin vibrio harveyi 1.2 1.2 1 PMID:18205958 -3.2.1.14 chitohexaose coccidioides immitis 0.5 0.5 1 PMID:11327866 -3.2.1.14 chitohexaose nepenthes alata 0.68 0.68 1 PMID:23026711 -3.2.1.14 chitohexaose vibrio harveyi 2.9 2.9 1 PMID:18205958 -3.2.1.14 chitopentaose aeromonas media 4.47 4.47 1 PMID:35578780 -3.2.1.14 chitosan thermococcus chitonophagus 0.0025 0.0025 1 PMID:12579379 -3.2.1.14 cm-chitin-rbv annona cherimola 366.7 366.7 1 PMID:20576315 -3.2.1.14 colloidal chitin aeromonas media 4.6 4.6 1 PMID:35578780 -3.2.1.14 colloidal chitin bacillus thuringiensis 4.24 4.24 1 PMID:28377239 -3.2.1.14 colloidal chitin caldicellulosiruptor acetigenus 0.28 0.28 1 PMID:34627844 -3.2.1.14 colloidal chitin candida albicans 7.5 7.5 1 PMID:37876300 -3.2.1.14 colloidal chitin corallococcus sp. egb 4.41 0.98 4 PMID:30980875 -3.2.1.14 colloidal chitin hydrogenophilus hirschii 14400.0 14400.0 1 PMID:28827133 -3.2.1.14 colloidal chitin paenibacillus barengoltzii 0.019 0.019 1 PMID:27320843 -3.2.1.14 colloidal chitin paenibacillus timonensis 87800.0 87800.0 1 PMID:31349143 -3.2.1.14 colloidal chitin paenibacillus xylanexedens 0.08 0.08 1 PMID:34022308 -3.2.1.14 colloidal chitin penicillium ochrochloron 2.37 2.37 1 * -3.2.1.14 colloidal chitin penicillium oxalicum 0.22 0.22 1 PMID:34201595 -3.2.1.14 colloidal chitin rhizomucor miehei 0.53 0.2695 2 PMID:26709620;PMID:34358705 -3.2.1.14 colloidal chitin scorpaena scrofa 5.33 5.33 1 PMID:22972353 -3.2.1.14 colloidal chitin trichoderma virens 8.08 8.08 1 PMID:29551512 -3.2.1.14 colloidal chitin vibrio harveyi 0.1 0.1 1 PMID:19568782 -3.2.1.14 ethlene glycol chitin nepenthes alata 0.1 0.1 1 PMID:23026711 -3.2.1.14 fitc-chitin drosera rotundifolia 76.7 60.95 2 PMID:32553964 -3.2.1.14 glcnacbeta(1-4)glcnacbeta(1-4)glcnacbeta(1-4)glcnacbeta(1-4)glcnac vibrio harveyi 0.21 0.21 1 PMID:19568782 -3.2.1.14 glcnacbeta(1-4)glcnacbeta(1-4)glcnacbeta(1-4)glcnacbeta(1-4)glcnacbeta(1-4)glcnac vibrio harveyi 0.19 0.19 1 PMID:19568782 -3.2.1.14 glycol chitin bacillus cereus 0.075 0.075 1 * -3.2.1.14 glycol chitin bombyx mori 0.084 0.07150000000000001 2 PMID:9443376 -3.2.1.14 glycol chitin dioscorea polystachya 0.2 0.2 1 PMID:25036674 -3.2.1.14 glycol chitin paenibacillus barengoltzii 0.016 0.016 1 PMID:27320843 -3.2.1.14 glycol chitin pennahia argentata 2.33 2.33 1 PMID:19297695 -3.2.1.14 glycol chitin rhizomucor miehei 0.016 0.016 1 PMID:26709620 -3.2.1.14 glycolchitin hexagrammos otakii 3.15 1.85 3 PMID:16636466 -3.2.1.14 glycolchitin scomber japonicus 2.21 2.21 1 PMID:16636466 -3.2.1.14 methylumbelliferyl-beta-n',n',n'-triacetyl-chitotrioside tenebrio molitor 1500.0 1500.0 1 PMID:17027845 -3.2.1.14 methylumbelliferyl-beta-n',n'-diacetyl-chitobioside tenebrio molitor 350.0 350.0 1 PMID:17027845 -3.2.1.14 methylumbelliferyl-beta-n'-acetylglucosamine tenebrio molitor 300.0 300.0 1 PMID:17027845 -3.2.1.14 n,n',n'',n''',n''''-pentaacetylchitopentaose hevea brasiliensis 0.77 0.445 4 PMID:11846790 -3.2.1.14 p-nitrophenol-beta-d-galactopyranoside thermococcus chitonophagus 0.017 0.017 1 PMID:12579379 -3.2.1.14 p-nitrophenol-beta-d-glucopyranoside thermococcus chitonophagus 0.095 0.095 1 PMID:12579379 -3.2.1.14 p-nitrophenol-beta-d-lactopyranoside thermococcus chitonophagus 0.025 0.025 1 PMID:12579379 -3.2.1.14 p-nitrophenol-beta-d-maltoside thermococcus chitonophagus 0.07 0.07 1 PMID:12579379 -3.2.1.14 p-nitrophenol-beta-d-mannopyranoside thermococcus chitonophagus 0.032 0.032 1 PMID:12579379 -3.2.1.14 p-nitrophenol-beta-d-n,n'-diacetylchitobioside thermococcus chitonophagus 0.383 0.383 1 PMID:12579379 -3.2.1.14 p-nitrophenyl-n,n'-diacetylchitobiose vibrio harveyi 2.15 2.15 1 PMID:17490819 -3.2.1.14 reduced chitopentaose niallia circulans 45.1 35.6 3 PMID:12930197 -3.2.1.14 reduced n-acetylchitopentaose oryza sativa 4.32 4.32 1 PMID:18211919 -3.2.1.140 4-nitrophenyl-beta-lacto-n-bioside [clostridium] nexile 27.0 27.0 1 PMID:35092420 -3.2.1.140 4-nitrophenyl-beta-lacto-n-bioside [ruminococcus] lactaris 17.0 17.0 1 PMID:35092420 -3.2.1.140 4-nitrophenyl-beta-lacto-n-bioside bifidobacterium bifidum 16.0 16.0 1 PMID:25839135 -3.2.1.140 4-nitrophenyl-beta-lacto-n-bioside bifidobacterium longum subsp. longum 88.0 70.0 2 PMID:25839135;PMID:35092420 -3.2.1.140 4-nitrophenyl-beta-lacto-n-bioside bifidobacterium saguini 5.0 5.0 1 PMID:35092420 -3.2.1.140 4-nitrophenyl-gal-beta-(1->3)-galnac bifidobacterium bifidum 4.9 4.9 1 PMID:25839135 -3.2.1.140 4-nitrophenyl-gal-beta-(1->3)-galnac bifidobacterium longum subsp. longum 1.5 1.5 1 PMID:25839135 -3.2.1.140 4-nitrophenyl-galacto-n-bioside [clostridium] nexile 3.9 3.9 1 PMID:35092420 -3.2.1.140 4-nitrophenyl-galacto-n-bioside [ruminococcus] lactaris 7.7 7.7 1 PMID:35092420 -3.2.1.140 4-nitrophenyl-galacto-n-bioside bifidobacterium longum subsp. longum 3.1 3.1 1 PMID:35092420 -3.2.1.140 4-nitrophenyl-galacto-n-bioside bifidobacterium saguini 5.1 5.1 1 PMID:35092420 -3.2.1.140 4-nitrophenyl-galnac-beta-(1->3)-glcnac bifidobacterium longum 39.4 39.4 1 PMID:23843461 -3.2.1.140 4-nitrophenyl-lacto-n-bioside bifidobacterium bifidum 90.0 85.0 2 PMID:33401671 -3.2.1.140 4-nitrophenyl-lacto-n-bioside bifidobacterium longum 96.1 96.1 1 PMID:23843461 -3.2.1.140 fuc-alpha-(1->2)-gal-beta-(1->3)-glcnac-beta-(1->3)-gal-beta-(1->4)-glc bifidobacterium longum subsp. longum 14.0 14.0 1 PMID:25839135 -3.2.1.140 gal-beta-(1->3)-galnac-beta-(1->3)-gal-alpha-(1->4)-gal-beta-(1->4)-glc bifidobacterium bifidum 0.29 0.29 1 PMID:25839135 -3.2.1.140 gal-beta-(1->3)-galnac-beta-(1->3)-gal-alpha-(1->4)-gal-beta-(1->4)-glc bifidobacterium longum subsp. longum 0.84 0.84 1 PMID:25839135 -3.2.1.140 gal-beta-(1->3)-glcnac-beta-(1->3)-gal-beta-(1->4)-glc bifidobacterium bifidum 42.0 42.0 1 PMID:25839135 -3.2.1.140 gal-beta-(1->3)-glcnac-beta-(1->3)-gal-beta-(1->4)-glc bifidobacterium longum subsp. longum 110.0 110.0 1 PMID:25839135 -3.2.1.140 lacto-n-fucopentaose i bifidobacterium longum 13.5 13.5 1 PMID:23843461 -3.2.1.140 lacto-n-tetraose bifidobacterium longum 282.0 197.5 2 PMID:23843461 -3.2.1.140 p-nitrophenyl-gal-(1,3)-beta-glcnac bifidobacterium bifidum 89.0 89.0 1 PMID:18469123 -3.2.1.140 p-nitrophenyl-lacto-n-bioside bifidobacterium bifidum jcm 1254 89.0 89.0 1 PMID:18469123 -3.2.1.141 maltoheptaose saccharolobus solfataricus 6.01 6.01 1 PMID:18563901 -3.2.1.141 maltohexaose saccharolobus solfataricus 18.2 18.2 1 PMID:18563901 -3.2.1.141 maltooligosyltrehalose saccharolobus solfataricus 947.0 947.0 1 PMID:23894317 -3.2.1.141 maltopentaose saccharolobus solfataricus 17.7 17.7 1 PMID:18563901 -3.2.1.141 maltopentaosyl trehalose saccharolobus solfataricus 1230.0 1230.0 1 PMID:16968069 -3.2.1.141 maltopentaosyltrehalose saccharolobus solfataricus 1226.0 1226.0 1 PMID:18563901 -3.2.1.141 maltosyl trehalose saccharolobus solfataricus 193.0 193.0 1 PMID:16968069 -3.2.1.141 maltotetraose saccharolobus solfataricus 5.49 5.49 1 PMID:16968069 -3.2.1.141 maltotetraosyl trehalose saccharolobus solfataricus 1190.0 1190.0 1 PMID:16968069 -3.2.1.141 maltotetraosyltrehalose saccharolobus solfataricus 1192.0 1192.0 1 PMID:18563901 -3.2.1.141 maltotriosyl trehalose saccharolobus solfataricus 1030.0 1030.0 1 PMID:16968069 -3.2.1.141 maltotriosyltrehalose saccharolobus solfataricus 1030.0 1030.0 1 PMID:18563901 -3.2.1.142 amylopectin hordeum vulgare 15.6 15.6 1 PMID:25562209 -3.2.1.142 amylopectin hordeum vulgare subsp. vulgare 9.4 9.4 1 PMID:31676454 -3.2.1.142 beta-limit dextrin hordeum vulgare subsp. vulgare 35.0 35.0 1 PMID:31676454 -3.2.1.142 pullulan hordeum vulgare 78.0 78.0 4 PMID:19733243;PMID:20863834;PMID:25562209 -3.2.1.142 pullulan hordeum vulgare subsp. vulgare 24.0 24.0 1 PMID:31676454 -3.2.1.143 poly(adp-ribose) bos taurus 90.0 90.0 1 PMID:3771556 -3.2.1.143 poly(adp-ribose) deinococcus radiodurans 266.4 266.4 1 PMID:30940816 -3.2.1.145 beta-(1-3)-d-galactotriose raphanus sativus 32.5 32.5 1 PMID:15980190 -3.2.1.145 beta-(1-3)-galactobiose raphanus sativus 28.6 28.6 1 PMID:15980190 -3.2.1.145 p-nitrophenyl-beta-galactoside raphanus sativus 123.0 123.0 1 PMID:15980190 -3.2.1.146 1-o-methyl-beta-d-galactofuranoside penicillium fellutanum 29.0 29.0 1 PMID:11571168 -3.2.1.146 4-nitrophenyl beta-d-galactofuranoside aspergillus nidulans 70.8 46.349999999999994 2 PMID:33011078 -3.2.1.146 4-nitrophenyl beta-d-galactofuranoside aspergillus niger 0.14 0.14 1 PMID:36521309 -3.2.1.146 4-nitrophenyl beta-d-galactofuranoside streptomyces sp. jha 19 3.5 3.5 1 PMID:31174175 -3.2.1.146 peptidophosphogalactomannan pp2gm penicillium fellutanum 14.0 14.0 1 PMID:11571168 -3.2.1.147 3-deoxyglucotropaeolin lepidium sativum 1.6 1.6 1 PMID:8641474 -3.2.1.147 4-deoxyglucotropaeolin lepidium sativum 3.1 3.1 1 PMID:8641474 -3.2.1.147 4-nitrophenyl beta-d-glucopyranoside arabidopsis thaliana 17.0 7.3 3 PMID:19703694 -3.2.1.147 4-nitrophenyl beta-d-glucopyranoside armoracia rusticana 4.21 4.21 1 PMID:24333031 -3.2.1.147 6-deoxyglucotropaeolin lepidium sativum 9.4 9.4 1 PMID:8641474 -3.2.1.147 gluconasturtiin armoracia rusticana 8.91 8.91 1 PMID:24333031 -3.2.1.147 glucoraphanin rahnella inusitata 1115.07 1115.07 1 PMID:35112855 -3.2.1.147 glucoraphenin rahnella inusitata 745.32 745.32 1 PMID:35112855 -3.2.1.147 glucotropaeolin brevicoryne brassicae 22.8 22.8 1 PMID:11179970 -3.2.1.147 glucotropaeolin lepidium sativum 65.6 65.6 1 PMID:8641474 -3.2.1.147 sinigrin arabidopsis thaliana 46.0 6.04 7 PMID:19703694;PMID:22682567 -3.2.1.147 sinigrin armoracia rusticana 10.69 10.69 1 PMID:24333031 -3.2.1.147 sinigrin brassica napus 187.0 187.0 1 PMID:11858716 -3.2.1.147 sinigrin brevicoryne brassicae 6.0 6.0 1 PMID:11179970 -3.2.1.147 sinigrin carica papaya 65.3 46.849999999999994 2 PMID:20883440 -3.2.1.147 sinigrin lepidium latifolium 0.75 0.54 2 PMID:26527478 -3.2.1.147 sinigrin rahnella inusitata 8075.85 8075.85 1 PMID:35112855 -3.2.1.147 sinigrin raphanus sativus 287.0 144.555 2 * -3.2.1.149 2-phenylethyl 6-o-beta-d-xylopyranosyl-beta-d-glucopyranoside camellia sinensis 43.7 43.7 1 PMID:11826969 -3.2.1.149 2-phenylethyl beta-primeveroside camellia sinensis 43.8 43.8 1 PMID:14579595 -3.2.1.149 2-phenylethyl beta-vicianoside camellia sinensis 43.7 5.85 3 PMID:11826969;PMID:14579595 -3.2.1.149 2-phenylethyl-6-o-alpha-d-arabinosyl-beta-d-glucopyranoside camellia sinensis 5.85 5.85 1 PMID:11826969 -3.2.1.15 alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonate fusarium verticillioides 21.6 21.6 1 PMID:11410340 -3.2.1.15 alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonate fusarium verticillioides 24.7 24.7 1 PMID:11410340 -3.2.1.15 alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonate fusarium verticillioides 81.1 81.1 1 PMID:11410340 -3.2.1.15 alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonate fusarium verticillioides 106.3 106.3 1 PMID:11410340 -3.2.1.15 alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonosyl-(1,4)-o-alpha-d-galacturonate fusarium verticillioides 122.5 122.5 1 PMID:11410340 -3.2.1.15 hexagalacturonate rhizopus arrhizus 45.7 45.7 1 * -3.2.1.15 pectin chondrostereum purpureum 230.0 20.2 3 PMID:26293910 -3.2.1.15 pectin kluyveromyces marxianus 6.08 6.08 1 PMID:11998843 -3.2.1.15 pectin penicillium oxalicum 552.3 552.3 1 PMID:24584459 -3.2.1.15 pentagalacturonate rhizopus arrhizus 35.8 35.8 1 * -3.2.1.15 poly-d-galacturonic acid penicillium rolfsii 7478.4 7478.4 1 PMID:36360082 -3.2.1.15 polygalacturonate aspergillus fumigatus 44.0 44.0 1 PMID:28330273 -3.2.1.15 polygalacturonate aspergillus japonicus 90.0 58.0 2 PMID:12882638 -3.2.1.15 polygalacturonate chondrostereum purpureum 1670.0 996.0 3 PMID:26293910 -3.2.1.15 polygalacturonate fusarium verticillioides 70.0 38.35 2 PMID:11168425;PMID:15462530 -3.2.1.15 polygalacturonic acid kluyveromyces marxianus 1.83 1.83 1 PMID:11998843 -3.2.1.15 polygalacturonic acid penicillium oxalicum 4068.0 3045.0 2 PMID:24584459 -3.2.1.15 polygalacturonic acid tetracoccosporium sp. 2.94 2.417 2 PMID:17299207 -3.2.1.15 polygalacturonic acid trichoderma harzianum 592.0 592.0 1 PMID:16872705 -3.2.1.15 tetragalacturonate rhizopus arrhizus 27.4 27.4 1 * -3.2.1.15 trigalacturonate rhizopus arrhizus 8.6 8.6 1 * -3.2.1.151 2-chloro-4-nitrophenyl glcbeta(1->4)glcbeta(1->4)glcbeta paenibacillus polymyxa 7.34 7.34 1 PMID:21795708 -3.2.1.151 2-chloro-4-nitrophenyl glcbeta(1->4)glcbeta(1->4)glcbeta(1->4)glcbeta paenibacillus polymyxa 15.93 15.93 1 PMID:21795708 -3.2.1.151 beta-glucan trichoderma reesei 306.0 306.0 1 PMID:17229143 -3.2.1.151 carboxyethyl cellulose acetivibrio thermocellus 0.22 0.22 1 PMID:16772298 -3.2.1.151 carboxymethyl cellulose acetivibrio thermocellus 0.72 0.72 1 PMID:16772298 -3.2.1.151 carboxymethyl cellulose aspergillus oryzae 21.9 21.9 1 PMID:32910269 -3.2.1.151 carboxymethyl cellulose trichoderma reesei 52.0 52.0 1 PMID:17229143 -3.2.1.151 hydroxyethyl cellulose cellvibrio japonicus 4.6 4.6 1 PMID:26929175 -3.2.1.151 hydroxyethyl cellulose trichoderma reesei 138.0 138.0 1 PMID:17229143 -3.2.1.151 laminarin trichoderma reesei 193.0 193.0 1 PMID:17229143 -3.2.1.151 lichenan acetivibrio thermocellus 0.59 0.59 1 PMID:16772298 -3.2.1.151 phosphoric acid-swollen cellulose trichoderma reesei 7.0 7.0 1 PMID:17229143 -3.2.1.151 tamarind seed xyloglucan aspergillus oryzae 112.0 97.2 2 PMID:32910269 -3.2.1.151 tamarind seed xyloglucan paenibacillus sp. 49.2 49.2 1 PMID:24657616 -3.2.1.151 tamarind xyloglucan uncultured bacterium 1.24 1.24 1 PMID:20039037 -3.2.1.151 xxxg trichoderma reesei 7.2 7.2 1 PMID:17229143 -3.2.1.151 xylalpha(1->6)glcbeta(1->4)[galbeta(1->2)xylalpha(1->6)]glcbeta(1->4)[galbeta(1->2)xylalpha(1->6)]glcbeta(1->4)glcbeta paenibacillus polymyxa 6.96 6.96 1 PMID:21795708 -3.2.1.151 xylalpha(1->6)glcbeta(1->4)xylalpha(1->6)glcbeta(1->4)xylalpha(1->6)glcbeta(1->4)glcbeta(1->4)xylalpha(1->6)glcbeta(1->4)xylalpha(1->6)glcbeta(1->4)xylalpha(1->6)glcbeta(1->4)glcbeta paenibacillus polymyxa 14.01 14.01 1 PMID:21795708 -3.2.1.151 xyloglucan acetivibrio thermocellus 0.78 0.78 1 PMID:16772298 -3.2.1.151 xyloglucan aspergillus aculeatus 113.0 113.0 1 PMID:9884411 -3.2.1.151 xyloglucan aspergillus fumigatus 16.4 16.4 1 PMID:28013403 -3.2.1.151 xyloglucan aspergillus japonicus 53.0 53.0 1 PMID:15541296 -3.2.1.151 xyloglucan aspergillus niger 49.0 41.5 2 PMID:18072936;PMID:19433323 -3.2.1.151 xyloglucan cellvibrio japonicus 77.6 77.6 1 PMID:26929175 -3.2.1.151 xyloglucan paenibacillus odorifer 39.8 39.8 1 PMID:30463871 -3.2.1.151 xyloglucan paenibacillus sp. 77.6 12.7 3 PMID:16332739 -3.2.1.151 xyloglucan phanerodontia chrysosporium 31.9 30.0 2 PMID:17922847 -3.2.1.151 xyloglucan trichoderma reesei 805.0 805.0 1 PMID:17229143 -3.2.1.151 xyloglucan tropaeolum majus 0.08 0.0465 2 PMID:17557806 -3.2.1.151 xyloglucan octasaccharide xxxgxxxg fragaria chiloensis 8210.0 8210.0 1 PMID:32403246 -3.2.1.155 beta-glucan chrysosporium lucknowense 30.0 30.0 1 PMID:15541296 -3.2.1.155 beta-glucan trichoderma reesei 12.0 12.0 1 PMID:15541296 -3.2.1.155 carboxymethylcellulose trichoderma reesei 46.0 46.0 1 PMID:15541296 -3.2.1.155 xyloglucan chrysosporium lucknowense 99.0 99.0 1 PMID:15541296 -3.2.1.155 xyloglucan paenibacillus sp. 77.6 40.3 2 PMID:16332739 -3.2.1.155 xyloglucan trichoderma reesei 55.0 55.0 1 PMID:15541296 -3.2.1.156 beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranose halalkalibacterium halodurans 163.0 163.0 1 PMID:15491996 -3.2.1.156 beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranose halalkalibacterium halodurans 162.0 162.0 1 PMID:15491996 -3.2.1.156 beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranose halalkalibacterium halodurans 73.0 73.0 1 PMID:15491996 -3.2.1.156 beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranosyl-(1-4)-beta-d-xylopyranose halalkalibacterium halodurans 175.0 175.0 1 PMID:15491996 -3.2.1.156 corncob xylan paenibacillus physcomitrellae 168.36 168.36 1 PMID:35785629 -3.2.1.156 d-xylose halalkalibacterium halodurans 5.04 5.04 1 PMID:18263897 -3.2.1.156 oat spelt xylan pseudoalteromonas haloplanktis 166.0 166.0 1 PMID:20552357 -3.2.1.156 oat spelt xylan uncultured bacterium 138.0 138.0 1 PMID:20552357 -3.2.1.156 wheat flour arabinoxylan pseudoalteromonas haloplanktis 1455.0 1455.0 1 PMID:20552357 -3.2.1.156 wheat flour arabinoxylan uncultured bacterium 1099.0 1099.0 1 PMID:20552357 -3.2.1.156 xylotriose paenibacillus barcinonensis 118.8 118.8 1 PMID:27316951 -3.2.1.157 iota-carrageenan alteromonas fortis 726.6 726.6 1 PMID:20681629 -3.2.1.157 iota-carrageenan wenyingzhuangia fucanilytica 560.75 560.75 1 PMID:28760444 -3.2.1.158 agarose catenovulum agarivorans 2.4 2.4 1 PMID:31453692 -3.2.1.158 agarose thalassomonas sp. ld5 576.96 428.08000000000004 2 PMID:34863832 -3.2.1.161 4-nitrophenyl-beta-d-fucoside dalbergia nigrescens 7.0 7.0 1 PMID:16098548 -3.2.1.161 4-nitrophenyl-beta-d-glucopyranoside dalbergia nigrescens 10.4 10.4 1 PMID:16098548 -3.2.1.161 daidzin dalbergia nigrescens 480.0 480.0 1 PMID:16098548 -3.2.1.161 dalnigrein 7-o-beta-d-apiofuranosyl-(1->6)-beta-d-glucopyranoside dalbergia nigrescens 229.0 229.0 1 PMID:17998137 -3.2.1.161 dalpaniculin-7-o-[beta-d-apiofuranosyl-(1-6)-beta-d-glucopyranoside] dalbergia nigrescens 334.0 334.0 1 PMID:16098548 -3.2.1.161 dalpatein 7-o-beta-d-apiofuranosyl-(1->6)-beta-d-glucopyranoside dalbergia nigrescens 20.0 20.0 1 PMID:17998137 -3.2.1.161 dalpatein-7-o-[beta-d-apiofuranosyl-(1-6)-beta-d-glucopyranoside] dalbergia nigrescens 465.0 465.0 1 PMID:16098548 -3.2.1.161 genistin dalbergia nigrescens 500.0 500.0 1 PMID:16098548 -3.2.1.161 p-nitrophenyl 6-o-beta-d-xylopyranosyl-beta-d-glucopyranoside viburnum furcatum 0.098 0.042 5 PMID:18667453 -3.2.1.163 4-methylumbelliferyl alpha-d-mannopyranosyl-(1->6)-beta-d-mannopyranoside clostridium perfringens 4.9 4.9 1 PMID:23816041 -3.2.1.165 4-nitrophenyl beta-d-glucosaminide photobacterium profundum 0.087 0.087 1 PMID:21098515 -3.2.1.165 4-nitrophenyl beta-d-glucoside photobacterium profundum 0.19 0.19 1 PMID:21098515 -3.2.1.165 cellobiose photobacterium profundum 68.8 68.8 1 PMID:21098515 -3.2.1.165 cellotetraose photobacterium profundum 54.2 54.2 1 PMID:21098515 -3.2.1.165 cellotriose photobacterium profundum 47.7 47.7 1 PMID:21098515 -3.2.1.165 chitobiose photobacterium profundum 152.9 119.95 2 PMID:21098515;PMID:26621872 -3.2.1.165 chitohexaose amycolatopsis orientalis 27.0 27.0 1 PMID:18359118 -3.2.1.165 chitosan aspergillus fumigatus 28.3 28.3 1 PMID:16289917 -3.2.1.165 colloidal chitosan aspergillus oryzae 23.8 23.8 1 PMID:26597529 -3.2.1.165 crab shell chitosan aspergillus fumigatus 3000.0 3000.0 1 PMID:28330083 -3.2.1.165 glcn(beta1-4)glcn(beta1-4)glcn photobacterium profundum 77.4 77.4 1 PMID:21098515 -3.2.1.165 glcn(beta1-4)glcn(beta1-4)glcn(beta1-4)glcn photobacterium profundum 52.0 52.0 1 PMID:21098515 -3.2.1.165 glcn(beta1-4)glcn(beta1-4)glcn(beta1-4)glcn(beta1-4)glcn photobacterium profundum 97.6 97.6 1 PMID:21098515 -3.2.1.166 2'-n,6'-o-bis-sulfated heparin sulfate disaccharide homo sapiens 0.000331 0.000331 1 PMID:33073275 -3.2.1.166 fondaparinux homo sapiens 1.72 1.72 1 PMID:35382258 -3.2.1.166 methyl 2-deoxy-6-o-sulfo-2-(sulfoamino)-alpha-d-glucopyranosyl-(1,4)-beta-d-glucopyranuronosyl-(1,4)-2-deoxy-3,6-di-o-sulfo-2-(sulfoamino)-d-glucopyranosyl-(1,4)-2-o-sulfo-alpha-l-idopyranuronosyl-(1,4)-2-deoxy-6-o-sulfo-2-(sulfoamino)-alpha-d-glucopyranoside homo sapiens 3.5 3.5 1 PMID:19748475 -3.2.1.167 4-nitrophenyl beta-d-glucuronide levilactobacillus brevis 53.7 42.75 2 PMID:24253830 -3.2.1.167 5,6,7-trihydroxyflavone 7-o-beta-d-glucoronate scutellaria baicalensis 639.0 639.0 1 PMID:10858442 -3.2.1.167 baicalin levilactobacillus brevis 21.3 19.9 2 PMID:24253830 -3.2.1.167 wogonoside levilactobacillus brevis 6.37 6.37 1 PMID:24253830 -3.2.1.168 hesperidin acremonium sp. 32.4 32.4 1 PMID:20358178 -3.2.1.168 hesperidin acremonium sp. dsm 24697 125.0 125.0 1 PMID:31705182 -3.2.1.168 hesperidin methylchalcone acremonium sp. 68.2 68.2 1 PMID:20358178 -3.2.1.168 rutin acremonium sp. dsm 24697 4.39 4.39 1 PMID:31705182 -3.2.1.169 4-methylumbelliferyl n-acetyl-beta-d-glucosaminide clostridium perfringens 10.5 10.5 1 PMID:16541109 -3.2.1.169 4-methylumbelliferyl-n-acetyl-beta-d-glucosaminide clostridium perfringens 10.5 10.5 1 PMID:19275764 -3.2.1.169 4-nitrophenyl n-acetyl-beta-d-glucosaminide clostridium perfringens 0.2 0.2 1 PMID:16541109 -3.2.1.169 4-nitrophenyl n-acetyl-beta-d-glucosaminide homo sapiens 3.4 0.985 9 PMID:11788610;PMID:16584714;PMID:28346407;PMID:30644846 -3.2.1.169 4-nitrophenyl n-acetyl-beta-d-glucosaminide mus musculus 54.9 54.9 1 PMID:16517082 -3.2.1.169 fluorescein di(n-acetyl-beta-d-glucosaminide) homo sapiens 2.1 1.7000000000000002 2 PMID:16584714 -3.2.1.17 p-nitrophenyl-glcnacbeta(1-4)glcnacbeta(1-4)glcnacbeta(1-4)glcnacbeta(1-4)glcnacbeta homo sapiens 0.015 0.015 1 PMID:18248331 -3.2.1.17 p-nitrophenyl-n,n',n'',n''',n''''-pentaacetylchitopentaose liolophura japonica 0.076 0.076 1 * -3.2.1.172 2-o-(4-deoxy-beta-l-threo-hex-4-enopyranuronosyl)-alpha-l-rhamnopyranose bacillus subtilis 13.9 7.09 2 PMID:16781735 -3.2.1.173 alpha-d-gala-[(1->2)-alpha-l-rha-(1->4)-alpha-d-gala-]2-(1->2)-alpha-l-rha aspergillus aculeatus 2.4 2.4 1 PMID:9576784 -3.2.1.173 alpha-d-gala-[(1->2)-alpha-l-rha-(1->4)-alpha-d-gala-]3-(1->2)-alpha-l-rha aspergillus aculeatus 1.5 1.5 1 PMID:9576784 -3.2.1.173 alpha-d-gala-[(1->2)-alpha-l-rha-(1->4)-alpha-d-gala-]5-(1->2)-alpha-l-rha aspergillus aculeatus 1.8 1.8 1 PMID:9576784 -3.2.1.176 2,4-dinitrophenyl beta-lactoside trichoderma reesei 104.0 104.0 1 * -3.2.1.176 2-chloro-4-nitrophenyl beta-d-cellobioside geotrichum candidum 0.11 0.11 1 PMID:26367132 -3.2.1.176 2-chloro-4-nitrophenyl beta-d-lactoside melanocarpus albomyces 0.017 0.017 1 PMID:19148633 -3.2.1.176 2-chloro-4-nitrophenyl beta-d-lactoside trichoderma harzianum 0.74 0.74 1 PMID:23114223 -3.2.1.176 2-chloro-4-nitrophenyl beta-lactoside trichoderma reesei 12.8 12.8 1 * -3.2.1.176 2-chloro-4-nitrophenyl-beta-d-lactoside phialemonium thermophilum 0.0467 0.0467 1 PMID:18512263 -3.2.1.176 2-chloro-4-nitrophenyl-beta-d-lactoside thermoascus aurantiacus 0.0283 0.0283 1 PMID:18512263 -3.2.1.176 2-chloro-4-nitrophenyl-beta-d-lactoside thermochaetoides thermophila 0.3167 0.3167 1 PMID:18512263 -3.2.1.176 2-chloro-4-nitrophenyl-beta-d-lactoside trichoderma reesei 0.043 0.043 1 PMID:18512263 -3.2.1.176 2-chloro-4-nitrophenyl-beta-lactoside trichoderma harzianum 0.74 0.74 1 PMID:23114223 -3.2.1.176 4-bromophenyl beta-lactoside trichoderma reesei 1.7 1.7 1 * -3.2.1.176 4-methylumbelliferyl beta-d-cellobioside thermothielavioides terrestris 0.35 0.35 1 PMID:26265428 -3.2.1.176 4-methylumbelliferyl beta-d-lactopyranoside melanocarpus albomyces 0.14 0.14 1 PMID:19148633 -3.2.1.176 4-methylumbelliferyl beta-d-lactopyranoside trichoderma reesei 0.49 0.49 1 PMID:23532843 -3.2.1.176 4-methylumbelliferyl beta-d-lactoside rasamsonia emersonii 1.35 0.435 5 PMID:23974371 -3.2.1.176 4-methylumbelliferyl beta-d-lactoside trichoderma reesei 0.492 0.4535 2 PMID:23532843 -3.2.1.176 4-methylumbelliferyl beta-lactoside trichoderma reesei 47.0 47.0 1 * -3.2.1.176 4-methylumbelliferyl-beta-d-lactoside phialemonium thermophilum 0.1883 0.1883 1 PMID:18512263 -3.2.1.176 4-methylumbelliferyl-beta-d-lactoside thermoascus aurantiacus 0.325 0.325 1 PMID:18512263 -3.2.1.176 4-methylumbelliferyl-beta-d-lactoside thermochaetoides thermophila 1.15 1.15 1 PMID:18512263 -3.2.1.176 4-methylumbelliferyl-beta-d-lactoside trichoderma reesei 0.4783 0.4783 1 PMID:18512263 -3.2.1.176 4-nitrophenyl beta-d-cellobioside geotrichum candidum 0.1 0.1 1 PMID:26367132 -3.2.1.176 4-nitrophenyl beta-d-cellobioside thermothelomyces thermophilus 0.112 0.112 1 PMID:29222836 -3.2.1.176 4-nitrophenyl beta-d-cellobioside trichoderma harzianum 0.39 0.39 1 PMID:23114223 -3.2.1.176 4-nitrophenyl beta-d-lactopyranoside talaromyces funiculosus 0.273 0.273 1 PMID:29567941 -3.2.1.176 4-nitrophenyl beta-d-lactopyranoside trichoderma reesei 0.238 0.238 1 PMID:29567941 -3.2.1.176 4-nitrophenyl beta-d-lactoside dictyostelium discoideum 0.27 0.27 1 PMID:27037126 -3.2.1.176 4-nitrophenyl beta-d-lactoside dictyostelium purpureum 0.51 0.51 1 PMID:27037126 -3.2.1.176 4-nitrophenyl beta-d-lactoside geotrichum candidum 0.19 0.19 1 PMID:26367132 -3.2.1.176 4-nitrophenyl beta-lactoside trichoderma reesei 3.5 2.14 2 PMID:30538133 -3.2.1.176 4-nitrophenyl d-cellobioside trichoderma harzianum 0.39 0.39 1 PMID:23114223 -3.2.1.176 4-nitrophenyl lactopyranoside trichoderma reesei 142.0 142.0 1 PMID:31816027 -3.2.1.176 4-nitrophenyl-beta-d-lactoside rasamsonia emersonii 13.4 13.4 2 PMID:12007616 -3.2.1.176 amorphous cellulose phanerodontia chrysosporium 2.0 2.0 1 PMID:21051539 -3.2.1.176 amorphous cellulose trichoderma reesei 5.1 3.4499999999999997 2 PMID:21051539;PMID:24228828 -3.2.1.176 avicel trichoderma reesei 4.75 2.81 2 PMID:24228828;PMID:28844741 -3.2.1.176 bacterial cellulose phanerodontia chrysosporium 2.6 2.6 1 PMID:21051539 -3.2.1.176 bacterial cellulose trichoderma reesei 2.8 2.8 1 PMID:21051539 -3.2.1.176 bacterial microcrystalline cellulose trichoderma reesei 2.4 2.4 1 PMID:24228828 -3.2.1.176 carboxymethyl cellulose penicillium digitatum 52.0 52.0 1 PMID:32378080 -3.2.1.177 4-nitrophenyl alpha-d-xylopyranoside aspergillus oryzae 186.0 93.2145 2 PMID:31781819;PMID:38239767 -3.2.1.177 4-nitrophenyl alpha-d-xylopyranoside uncultured microorganism 154.0 154.0 1 PMID:27074950 -3.2.1.177 4-nitrophenyl-alpha-d-glucopyranoside escherichia coli 0.046 0.046 1 PMID:15501829 -3.2.1.177 4-nitrophenyl-alpha-d-xylopyranoside cellvibrio japonicus 0.58 0.58 1 PMID:21426303 -3.2.1.177 4-nitrophenyl-alpha-d-xyloside escherichia coli 0.173 0.1515 2 PMID:15294295;PMID:15501829 -3.2.1.177 alpha-d-xylopyranosyl fluoride escherichia coli 195.0 135.0 2 PMID:15294295;PMID:15501829 -3.2.1.177 isoprimeverose aspergillus oryzae 3.47 3.47 1 PMID:31781819 -3.2.1.177 isoprimeverose cellvibrio japonicus 2.94 2.94 1 PMID:21426303 -3.2.1.177 isoprimeverose escherichia coli 51.3 51.3 1 PMID:15294295 -3.2.1.177 isoprimeverose uncultured microorganism 7.69 7.69 1 PMID:27074950 -3.2.1.177 xyl-alpha-(1->6)-glc-beta-(1->4)-glc cellvibrio japonicus 9.39 9.39 1 PMID:21426303 -3.2.1.177 xyloglucan oligosaccharide xxxg aspergillus oryzae 2.28 2.28 1 PMID:31781819 -3.2.1.178 porphyran chondrus crispus 79.9 79.9 1 PMID:36402445 -3.2.1.178 porphyran phocaeicola plebeius 86.8 86.8 1 PMID:36709516 -3.2.1.178 porphyran wenyingzhuangia fucanilytica 50.14 50.14 1 PMID:32520542 -3.2.1.179 4-nitrophenyl beta-d-glucopyranoside microbacterium sp. xt11 23.2 23.2 1 PMID:35793414 -3.2.1.179 beta-d-4-deoxy-delta-4,5-glcap-(1->4)-beta-d-glcp-(1->4)-alpha-l-rhap-(1->3)-beta-d-glcp bacillus sp. (in: firmicutes) 7.3 7.3 1 PMID:15148314 -3.2.1.179 beta-d-4-deoxy-delta4,5-glcap-(1->3)-beta-d-galnac bacillus sp. (in: firmicutes) 14.1 14.1 1 PMID:21147778 -3.2.1.179 beta-d-4-deoxy-delta4,5-glcap-(1->3)-beta-d-galnac6s bacillus sp. (in: firmicutes) 54.9 54.9 1 PMID:21147778 -3.2.1.179 cellobiose microbacterium sp. xt11 7258.6 7258.6 1 PMID:35793414 -3.2.1.18 (trifluoromethyl)umbelliferyl alpha-sialoside trypanosoma cruzi 2.9 2.9 1 PMID:18284211 -3.2.1.18 3'-sialyllactose porphyromonas gingivalis 5.95 5.95 1 PMID:31517596 -3.2.1.18 4-methylumbelliferyl 3-deoxy-d-glycero-alpha-d-galacto-non-2-ulopyranosidonic acid aspergillus terreus 53.0 53.0 1 PMID:34724608 -3.2.1.18 4-methylumbelliferyl 3-deoxy-d-glycero-alpha-d-galacto-non-2-ulopyranosidonic acid trichophyton rubrum 1850.0 1850.0 1 PMID:34724608 -3.2.1.18 4-methylumbelliferyl alpha-d-n-acetylneuraminic acid aspergillus fumigatus 0.0743 0.0743 1 PMID:20652740 -3.2.1.18 4-methylumbelliferyl alpha-d-n-acetylneuraminic acid bacteroides thetaiotaomicron 146.7 146.7 1 PMID:23665536 -3.2.1.18 4-methylumbelliferyl alpha-d-n-acetylneuraminic acid bifidobacterium bifidum 33.0 33.0 1 PMID:30027820 -3.2.1.18 4-methylumbelliferyl alpha-d-n-acetylneuraminic acid homo sapiens 23.0 23.0 1 PMID:20511247 -3.2.1.18 4-methylumbelliferyl alpha-d-n-acetylneuraminic acid influenza a virus h1n1 30.58 15.739999999999998 2 PMID:26280677;PMID:29933553 -3.2.1.18 4-methylumbelliferyl alpha-d-n-acetylneuraminic acid influenza a virus h5n1 75.45 75.45 1 PMID:26280677 -3.2.1.18 4-methylumbelliferyl d-n-acetylneuraminyl-alpha-(2->3)-d-galactopyranoside aspergillus fumigatus 0.0004 0.0004 1 PMID:20652740 -3.2.1.18 4-methylumbelliferyl n-acetyl-alpha-d-neuraminic acid bacteroides fragilis 283.2 283.2 1 PMID:29678922 -3.2.1.18 4-methylumbelliferyl n-acetylneuraminic acid porphyromonas gingivalis 31.93 18.314999999999998 4 PMID:31517596 -3.2.1.18 4-methylumbelliferyl-alpha-d-n-acetylneuraminic acid salmonella enterica subsp. enterica serovar typhimurium 45.0 45.0 1 PMID:1769974 -3.2.1.18 4-nitrophenyl alpha-d-n-acetylneuraminic acid bacteroides thetaiotaomicron 82.4 82.4 1 PMID:23665536 -3.2.1.18 4-nitrophenyl alpha-d-n-acetylneuraminic acid photobacterium damselae 0.88 0.88 1 PMID:19880425 -3.2.1.18 4-nitrophenyl alpha-sialoside trypanosoma cruzi 1.57 1.57 1 PMID:18284211 -3.2.1.18 5-bromo-4-chloro-indolyl beta-d-galactopyranosyl-alpha-2,6-n-acetyl-neuraminic acid akkermansia muciniphila 246.0 24.15 4 PMID:26340137 -3.2.1.18 6'-sialyllactose porphyromonas gingivalis 1.24 1.24 1 PMID:31517596 -3.2.1.18 colominic acid bacteroides thetaiotaomicron 157.6 157.6 1 PMID:23665536 -3.2.1.18 fetuin influenza a virus 8.76 8.76 1 PMID:32302655 -3.2.1.18 sialic acid bacteroides fragilis 329.6 329.6 1 PMID:29678922 -3.2.1.18 sialyl-alpha-2,3-lactose bacteroides thetaiotaomicron 313.5 313.5 1 PMID:23665536 -3.2.1.18 sialyl-alpha-2,6-lactose bacteroides thetaiotaomicron 161.0 161.0 1 PMID:23665536 -3.2.1.180 2,4,6-trichlorophenyl 4-deoxy-alpha-l-threo-hex-4-enopyranosiduronic acid clostridium perfringens 0.312 0.312 1 PMID:24227702 -3.2.1.180 2,4-dinitrophenyl 4-deoxy-alpha-l-threo-hex-4-enopyranosiduronic acid clostridium perfringens 0.14 0.14 1 PMID:24227702 -3.2.1.180 2,5-dinitrophenyl 4-deoxy-alpha-l-threo-hex-4-enopyranosiduronic acid clostridium perfringens 0.64 0.64 1 PMID:24227702 -3.2.1.180 2-(acetylamino)-2-deoxy-3-o-(4-deoxy-alpha-l-threo-hex-4-enopyranuronosyl)-4-o-sulfo-d-galactopyranose clostridium perfringens 0.09 0.09 1 PMID:24227702 -3.2.1.180 2-(acetylamino)-2-deoxy-3-o-(4-deoxy-alpha-l-threo-hex-4-enopyranuronosyl)-6-o-sulfo-d-galactopyranose clostridium perfringens 112.0 112.0 1 PMID:24227702 -3.2.1.180 2-(acetylamino)-2-deoxy-3-o-(4-deoxy-alpha-l-threo-hex-4-enopyranuronosyl)-d-galactopyranose clostridium perfringens 8.5 8.5 1 PMID:24227702 -3.2.1.180 2-deoxy-4-o-(4-deoxy-alpha-l-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-d-glucopyranose clostridium perfringens 14.0 14.0 1 PMID:24227702 -3.2.1.180 3-nitrophenyl 4-deoxy-alpha-l-threo-hex-4-enopyranosiduronic acid clostridium perfringens 14.7 14.7 1 PMID:24227702 -3.2.1.180 4-chlorophenyl 4-deoxy-alpha-l-threo-hex-4-enopyranosiduronic acid clostridium perfringens 3.9 3.9 1 PMID:24227702 -3.2.1.180 4-nitrophenyl 4-deoxy-alpha-l-threo-hex-4-enopyranosiduronic acid clostridium perfringens 2.05 2.05 1 PMID:24227702 -3.2.1.180 4-tert-butylphenyl 4-deoxy-alpha-l-threo-hex-4-enopyranosiduronic acid clostridium perfringens 3.27 3.27 1 PMID:24227702 -3.2.1.180 benzyl 4-deoxy-alpha-l-threo-hex-4-enopyranosiduronic acid clostridium perfringens 18.6 18.6 1 PMID:24227702 -3.2.1.180 beta-d-4-deoxy-delta4,5-glcap-(1->3)-beta-d-galnac streptococcus agalactiae 2.69 2.69 1 PMID:21147778 -3.2.1.180 beta-d-4-deoxy-delta4,5-glcap-(1->3)-beta-d-galnac6s streptococcus agalactiae 24.0 17.1 2 PMID:19416976;PMID:21147778 -3.2.1.180 beta-d-4-deoxy-delta4,5-glcap-(1->3)-beta-d-galnac6s streptococcus pneumoniae 1.3 1.3 1 PMID:19416976 -3.2.1.180 beta-d-4-deoxy-delta4,5-glcap-(1->3)-beta-d-galnac6s streptococcus pyogenes 4.0 4.0 1 PMID:19416976 -3.2.1.180 deltaglcua-beta-(1->4)-glcn2s streptococcus agalactiae 3.8 3.8 1 PMID:24403065 -3.2.1.180 deltaglcua-beta-(1->4)-glcnac pedobacter heparinus 16.0 16.0 1 PMID:24403065 -3.2.1.180 phenyl 4-deoxy-alpha-l-threo-hex-4-enopyranosiduronic acid clostridium perfringens 4.3 4.3 1 PMID:24227702 -3.2.1.181 beta-d-galactopyranosyl-(1->3)-beta-d-galactopyranosyl-(1->3)-beta-d-galactopyranose flammulina velutipes 5.47 5.47 1 PMID:21653698 -3.2.1.181 beta-d-galactopyranosyl-(1->3)-beta-d-galactopyranosyl-(1->3)-beta-d-galactopyranosyl-(1->3)-beta-d-galactopyranose flammulina velutipes 6.5 6.5 1 PMID:21653698 -3.2.1.182 (2r)-4-hydroxy-3-oxo-3,4-dihydro-2h-1,4-benzoxazin-2-yl beta-d-glucopyranoside consolida orientalis 32.0 32.0 1 PMID:22415274 -3.2.1.182 (2r)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2h-1,4-benzoxazin-2-yl beta-d-glucopyranoside consolida orientalis 4.2 4.2 1 PMID:22415274 -3.2.1.182 2-nitrophenyl beta-d-glucoside secale cereale 204.2 181.6 2 * -3.2.1.182 4-nitrophenyl beta-d-fucoside secale cereale 86.5 76.65 2 * -3.2.1.182 4-nitrophenyl beta-d-galactoside secale cereale 3.5 3.4 2 * -3.2.1.182 4-nitrophenyl beta-d-glucoside secale cereale 99.2 72.8 3 PMID:16751439 -3.2.1.182 4-nitrophenyl beta-d-glucoside triticum aestivum 235.9 128.0 3 PMID:16751439 -3.2.1.182 dhurrin consolida orientalis 52.0 52.0 1 PMID:22415274 -3.2.1.182 diboa beta-d-glucoside secale cereale 172.0 170.5 2 * -3.2.1.182 diboa-glucoside secale cereale 48.8 48.8 1 PMID:16751439 -3.2.1.182 diboa-glucoside triticum aestivum 214.0 137.0 3 PMID:16751439 -3.2.1.182 dimboa beta-d-glucoside secale cereale 119.0 108.2 2 * -3.2.1.182 dimboa-glucoside secale cereale 338.0 338.0 1 PMID:16751439 -3.2.1.182 dimboa-glucoside triticum aestivum 1201.0 773.0 3 PMID:16751439 -3.2.1.182 dimboa-glucoside zea mays 29.16 29.16 1 PMID:10748038 -3.2.1.183 udp-n-acetyl-alpha-d-glucosamine acinetobacter baumannii 2.86 2.86 1 PMID:29764940 -3.2.1.183 udp-n-acetyl-alpha-d-glucosamine homo sapiens 11.8 11.8 1 PMID:26980148 -3.2.1.183 udp-n-acetyl-alpha-d-glucosamine neisseria meningitidis 4.7 4.7 1 PMID:15518580 -3.2.1.183 udp-n-acetyl-alpha-d-glucosamine rattus norvegicus 0.33 0.33 1 PMID:12603133 -3.2.1.184 udp-n,n'-diacetylbacillosamine legionella pneumophila 59.1 59.1 1 PMID:18275154 -3.2.1.185 beta-l-arabinofuranosyl-(1->2)-beta-l-arabinofuranose bifidobacterium longum 2.0 2.0 1 PMID:21914802 -3.2.1.185 beta-l-arabinofuranosyl-(1->2)-beta-l-arabinofuranosyl-l-hydroxyproline bifidobacterium longum 6.3 6.3 1 PMID:21914802 -3.2.1.185 beta-l-arabinofuranosyl-l-hydroxyproline bifidobacterium longum 0.013 0.013 1 PMID:21914802 -3.2.1.186 4-methylumbelliferyl beta-d-glucoside solanum torvum 8.3 8.3 3 PMID:16289258;PMID:27055587 -3.2.1.186 4-nitrophenyl beta-d-glucoside solanum torvum 9.1 9.1 3 PMID:16289258;PMID:27055587 -3.2.1.186 torvoside a solanum torvum 8.6 8.6 3 PMID:16289258;PMID:27055587 -3.2.1.186 torvoside h solanum torvum 7.7 7.7 1 PMID:16289258 -3.2.1.187 4-o-(beta-l-arabinofuranosyl-(1->2)-beta-l-arabinofuranosyl-(1->2)-beta-l-arabinofuranosyl)-(2s,4s)-4-hydroxyproline bifidobacterium longum 2.7 2.7 1 PMID:21149454 -3.2.1.191 ginsenoside rb1 clavibacter michiganensis 1025.0 1025.0 1 PMID:25820645 -3.2.1.191 ginsenoside rb3 panax notoginseng 3.9 3.9 1 PMID:38238334 -3.2.1.191 gypenoside xvii clavibacter michiganensis 22.0 22.0 1 PMID:25820645 -3.2.1.192 4-nitrophenyl alpha-l-arabinopyranoside thermotoga petrophila 63.76 63.76 1 PMID:31715079 -3.2.1.192 4-nitrophenyl beta-d-glucopyranoside pseudothermotoga thermarum 121.0 121.0 1 * -3.2.1.192 4-nitrophenyl beta-d-glucopyranoside thermoclostridium stercorarium 36.43 36.43 1 PMID:36371935 -3.2.1.192 4-nitrophenyl beta-d-glucopyranoside thermotoga petrophila 403.59 403.59 1 PMID:31715079 -3.2.1.192 4-nitrophenyl-beta-d-glucopyranoside gordonia terrae 6292.0 6292.0 1 PMID:25457989 -3.2.1.192 ginsenoside rb1 gordonia terrae 82.87 82.87 1 PMID:25457989 -3.2.1.192 ginsenoside rb1 thermoclostridium stercorarium 56.85 56.85 1 PMID:36371935 -3.2.1.192 ginsenoside rd gordonia terrae 6.06 6.06 1 PMID:25457989 -3.2.1.192 ginsenoside rg1 thermoclostridium stercorarium 26.32 26.32 1 PMID:36371935 -3.2.1.193 4-nitrophenyl beta-d-glucopyranoside paenibacillus mucilaginosus 61.63 61.63 1 PMID:32144753 -3.2.1.193 ginsenoside rb1 paenibacillus mucilaginosus 0.49 0.49 1 PMID:32144753 -3.2.1.193 ginsenoside rd paenibacillus mucilaginosus 1.58 1.58 1 PMID:32144753 -3.2.1.193 ginsenoside rg3 paenibacillus mucilaginosus 2.08 2.08 1 PMID:32144753 -3.2.1.194 4-nitrophenyl-beta-d-glucopyranoside gordonia terrae 6292.0 6292.0 1 PMID:25457989 -3.2.1.194 ginsenoside re gordonia terrae 7.3 7.3 1 PMID:25457989 -3.2.1.194 ginsenoside rg1 gordonia terrae 5.75 5.75 1 PMID:25457989 -3.2.1.195 ginsenoside rb1 aspergillus niger 22.269 15.5345 2 PMID:34280789 -3.2.1.196 de16 maltodextrin saccharolobus solfataricus 1.75 1.75 1 PMID:37463425 -3.2.1.196 de19 maltodextrin saccharolobus solfataricus 1.62 1.62 1 PMID:37463425 -3.2.1.196 de2 maltodextrin saccharolobus solfataricus 2.66 2.66 1 PMID:37463425 -3.2.1.196 de4 maltodextrin saccharolobus solfataricus 3.56 3.56 1 PMID:37463425 -3.2.1.196 de9 maltodextrin saccharolobus solfataricus 2.24 2.24 1 PMID:37463425 -3.2.1.196 g3-beta-cyclodextrin escherichia coli 38.0 38.0 1 PMID:20187119 -3.2.1.196 g4-beta-cyclodextrin escherichia coli 41.7 41.7 1 PMID:20187119 -3.2.1.196 maize amylopectin saccharolobus solfataricus 0.06 0.06 1 PMID:37463425 -3.2.1.196 potato amylopectin saccharolobus solfataricus 0.07 0.07 1 PMID:37463425 -3.2.1.197 beta-d-mannopyranosyl-(1->2)-beta-d-mannopyranosyl-(1->2)-beta-d-mannopyranosyl-(1->2)-d-mannopyranose dyadobacter fermentans 26.0 26.0 1 PMID:26476324 -3.2.1.197 beta-d-mannopyranosyl-(1->2)-beta-d-mannopyranosyl-(1->2)-d-mannopyranose dyadobacter fermentans 30.0 30.0 1 PMID:26476324 -3.2.1.197 beta-d-mannopyranosyl-(1->2)-d-mannopyranose dyadobacter fermentans 30.0 30.0 1 PMID:26476324 -3.2.1.198 4-methylumbelliferyl (alpha-d-glucopyranosyl)-(1->3)-alpha-d-mannopyranoside bacteroides xylanisolvens 0.0007 0.0007 1 PMID:25487964 -3.2.1.198 4-methylumbelliferyl (alpha-d-mannopyranosyl)-(1->3)-alpha-d-mannopyranoside bacteroides thetaiotaomicron 0.0015 0.0015 1 PMID:25487964 -3.2.1.198 4-methylumbelliferyl (alpha-d-mannopyranosyl)-(1->3)-alpha-d-mannopyranoside bacteroides xylanisolvens 0.0008 0.0008 1 PMID:25487964 -3.2.1.198 methyl alpha-d-mannopyranosyl-(1->3)-alpha-d-mannopyranosyl-(1,2)-alpha-d-mannopyranosyl-(1,2)-alpha-d-mannopyranoside bacteroides thetaiotaomicron 3.0 3.0 1 PMID:25487964 -3.2.1.199 4-nitrophenyl alpha-sulfoquinovoside agrobacterium tumefaciens 22.3 22.3 1 PMID:30276262 -3.2.1.199 4-nitrophenyl alpha-sulfoquinovoside escherichia coli 32.7 23.5 2 PMID:26878550;PMID:30276262 -3.2.1.2 4-nitrophenyl alpha-maltopyranoside pyrococcus furiosus 962.0 962.0 1 PMID:18156337 -3.2.1.2 amylopectin bacillus cereus 2739.0 2739.0 1 PMID:15449941 -3.2.1.2 amylopectin curculigo pilosa 550.0 550.0 1 * -3.2.1.2 amylopectin glycine max 1280.0 1280.0 1 PMID:15794648 -3.2.1.2 amylose curculigo pilosa 2400.0 2400.0 1 * -3.2.1.2 maltopentaose glycine max 1280.0 1280.0 1 PMID:15178253 -3.2.1.2 maltopentaose thermococcus sp. 3.85 3.85 1 PMID:24835094 -3.2.1.2 maltotetraose thermococcus sp. 3.95 3.95 1 PMID:24835094 -3.2.1.2 maltotriose thermococcus sp. 11.45 11.45 1 PMID:24835094 -3.2.1.2 starch curculigo pilosa 6540.0 6000.0 2 * -3.2.1.2 starch glycine max 1280.0 1280.0 1 * -3.2.1.2 starch hordeum vulgare 305.0 302.0 2 PMID:11713664 -3.2.1.20 1-o-alpha-d-glucopyranosyl-beta-d-fructofuranoside erwinia rhapontici 0.27 0.27 1 PMID:19625389 -3.2.1.20 3-o-alpha-d-glucopyranosyl-d-fructose erwinia rhapontici 0.38 0.38 1 PMID:19625389 -3.2.1.20 4-nitrophenyl alpha-d-galactopyranoside thermotoga maritima 10.48 10.48 1 PMID:10972187 -3.2.1.20 4-nitrophenyl alpha-d-glucopyranoside aplysia fasciata 163.0 163.0 1 PMID:16290308 -3.2.1.20 4-nitrophenyl alpha-d-glucopyranoside caldanaerobacter subterraneus subsp. tengcongensis 6.64 6.64 1 PMID:20541109 -3.2.1.20 4-nitrophenyl alpha-d-glucopyranoside ferroplasma acidiphilum 22.5 22.5 1 PMID:15954864 -3.2.1.20 4-nitrophenyl alpha-d-glucopyranoside saccharolobus solfataricus 33.0 33.0 1 PMID:16580018 -3.2.1.20 4-nitrophenyl alpha-d-glucopyranoside solanum tuberosum 69.6 69.6 1 PMID:11469591 -3.2.1.20 4-nitrophenyl alpha-d-glucopyranoside sulfolobus acidocaldarius 16.7 16.7 1 PMID:23396915 -3.2.1.20 4-nitrophenyl alpha-d-glucopyranoside sulfurisphaera tokodaii 0.0175 0.0175 1 PMID:23314368 -3.2.1.20 4-nitrophenyl alpha-d-glucopyranoside thermoplasma acidophilum 59.7 59.7 1 * -3.2.1.20 4-nitrophenyl alpha-d-glucopyranoside thermotoga maritima 9.12 9.12 1 PMID:10972187 -3.2.1.20 4-nitrophenyl alpha-d-glucopyranosyl-1,4-alpha-d-glucopyranoside aplysia fasciata 75.9 75.9 1 PMID:16290308 -3.2.1.20 4-nitrophenyl alpha-d-glucoside apis cerana indica 1.89 1.89 1 PMID:23419073 -3.2.1.20 4-nitrophenyl alpha-d-glucoside bifidobacterium longum subsp. longum 371.0 371.0 1 PMID:28283459 -3.2.1.20 4-nitrophenyl-alpha-d-glucopyranoside apis cerana japonica 13.0 13.0 1 PMID:17151473 -3.2.1.20 4-o-alpha-d-glucopyranosyl-d-fructose erwinia rhapontici 0.45 0.45 1 PMID:19625389 -3.2.1.20 4-o-alpha-d-glucopyranosyl-d-glucopyranose erwinia rhapontici 0.85 0.85 1 PMID:19625389 -3.2.1.20 4-o-alpha-d-glucopyranosyl-d-sorbitol erwinia rhapontici 0.2 0.2 1 PMID:19625389 -3.2.1.20 5-o-alpha-d-glucopyranosyl-d-fructose erwinia rhapontici 0.37 0.37 1 PMID:19625389 -3.2.1.20 6-o-alpha-d-glucopyranosyl-d-fructofuranoside erwinia rhapontici 0.58 0.58 1 PMID:19625389 -3.2.1.20 amylopectin aspergillus niveus 25.48 25.48 1 PMID:19757138 -3.2.1.20 amylopectin panicum miliaceum 24.2 24.2 1 PMID:15845403 -3.2.1.20 amylose panicum miliaceum 26.2 26.2 1 PMID:15845403 -3.2.1.20 glycogen aspergillus niveus 24.5 24.5 1 PMID:19757138 -3.2.1.20 isomaltose apis cerana indica 5.2 5.2 1 PMID:23419073 -3.2.1.20 isomaltose aspergillus niger 50.5 50.5 1 * -3.2.1.20 isomaltose bifidobacterium longum subsp. longum 9.3 9.3 1 PMID:28283459 -3.2.1.20 isomaltose panicum miliaceum 5.75 5.75 1 PMID:15845403 -3.2.1.20 isomaltose schizosaccharomyces pombe 216.0 216.0 1 * -3.2.1.20 isomaltose sulfurisphaera tokodaii 0.02 0.02 1 PMID:23314368 -3.2.1.20 isomaltose thermoplasma acidophilum 22.9 22.9 1 * -3.2.1.20 isomaltose thermus thermophilus hb27 361.0 309.0 2 PMID:18223075 -3.2.1.20 kojibiose apis cerana japonica 8.7 8.7 1 PMID:17151473 -3.2.1.20 kojibiose aspergillus niger 32.3 32.3 1 * -3.2.1.20 kojibiose panicum miliaceum 9.44 5.705 2 PMID:15845403 -3.2.1.20 kojibiose schizosaccharomyces pombe 433.0 433.0 1 * -3.2.1.20 kojibiose thermoplasma acidophilum 127.0 127.0 1 * -3.2.1.20 maltodextrin aspergillus niger 127.0 127.0 1 * -3.2.1.20 maltoheptaose aspergillus niger 146.0 146.0 1 * -3.2.1.20 maltoheptaose dysdercus peruvianus 3.42 3.42 1 * -3.2.1.20 maltoheptaose hordeum vulgare 6.67 6.67 1 * -3.2.1.20 maltoheptaose panicum miliaceum 47.5 47.5 1 PMID:15845403 -3.2.1.20 maltoheptaose phaffia rhodozyma 10.0 10.0 1 PMID:16491468 -3.2.1.20 maltoheptaose schizosaccharomyces pombe 1020.0 1020.0 1 * -3.2.1.20 maltoheptaose solanum tuberosum 35.2 35.2 1 PMID:11469591 -3.2.1.20 maltoheptaose sulfurisphaera tokodaii 0.02 0.02 1 PMID:23314368 -3.2.1.20 maltohexaose aspergillus niger 170.0 170.0 1 * -3.2.1.20 maltohexaose dysdercus peruvianus 3.97 3.97 1 * -3.2.1.20 maltohexaose hordeum vulgare 6.26 6.26 1 * -3.2.1.20 maltohexaose panicum miliaceum 36.1 36.1 1 PMID:15845403 -3.2.1.20 maltohexaose schizosaccharomyces pombe 874.0 874.0 1 * -3.2.1.20 maltohexaose solanum tuberosum 57.2 57.2 1 PMID:11469591 -3.2.1.20 maltohexaose sulfolobus acidocaldarius 372.0 372.0 1 PMID:23396915 -3.2.1.20 maltohexaose sulfurisphaera tokodaii 0.02 0.02 1 PMID:23314368 -3.2.1.20 maltooctaose aspergillus niger 127.0 127.0 1 * -3.2.1.20 maltopentaose apis cerana japonica 15.0 14.0 2 PMID:17151473 -3.2.1.20 maltopentaose aspergillus niger 147.0 147.0 1 * -3.2.1.20 maltopentaose caldanaerobacter subterraneus subsp. tengcongensis mb4 316.0 316.0 1 PMID:20075617 -3.2.1.20 maltopentaose dysdercus peruvianus 1.05 1.05 1 * -3.2.1.20 maltopentaose hordeum vulgare 7.15 7.15 1 * -3.2.1.20 maltopentaose schizosaccharomyces pombe 810.0 810.0 1 * -3.2.1.20 maltopentaose solanum tuberosum 64.3 64.3 1 PMID:11469591 -3.2.1.20 maltopentaose sulfolobus acidocaldarius 611.0 611.0 1 PMID:23396915 -3.2.1.20 maltopentaose sulfurisphaera tokodaii 0.02 0.02 1 PMID:23314368 -3.2.1.20 maltose apis cerana japonica 22.0 22.0 1 PMID:17151473 -3.2.1.20 maltose aplysia fasciata 489.0 489.0 1 PMID:16290308 -3.2.1.20 maltose aspergillus niger 144.0 144.0 1 * -3.2.1.20 maltose aspergillus niveus 13.66 13.66 1 PMID:19757138 -3.2.1.20 maltose bifidobacterium longum subsp. longum 5.0 5.0 1 PMID:28283459 -3.2.1.20 maltose caldanaerobacter subterraneus subsp. tengcongensis mb4 253.5 253.5 1 PMID:20075617 -3.2.1.20 maltose dysdercus peruvianus 18.0 18.0 1 * -3.2.1.20 maltose ferroplasma acidiphilum 126.0 126.0 1 PMID:15954864 -3.2.1.20 maltose hordeum vulgare 81.7 25.0 3 PMID:10806244;PMID:16343940 -3.2.1.20 maltose panicum miliaceum 33.5 33.5 1 PMID:15845403 -3.2.1.20 maltose phaffia rhodozyma 15.3 15.3 1 PMID:16491468 -3.2.1.20 maltose schizosaccharomyces pombe 709.0 709.0 1 * -3.2.1.20 maltose solanum tuberosum 35.9 35.9 1 PMID:11469591 -3.2.1.20 maltose sulfolobus acidocaldarius 1278.0 1278.0 1 PMID:23396915 -3.2.1.20 maltose sulfurisphaera tokodaii 0.11 0.11 1 PMID:23314368 -3.2.1.20 maltose thermoplasma acidophilum 143.0 143.0 1 * -3.2.1.20 maltose thermus thermophilus hb27 22.0 16.5 2 PMID:18223075 -3.2.1.20 maltotetraose apis cerana indica 2.84 2.84 1 PMID:23419073 -3.2.1.20 maltotetraose apis cerana japonica 15.0 14.0 2 PMID:17151473 -3.2.1.20 maltotetraose aspergillus niger 193.0 193.0 1 * -3.2.1.20 maltotetraose caldanaerobacter subterraneus subsp. tengcongensis mb4 330.1 330.1 1 PMID:20075617 -3.2.1.20 maltotetraose dysdercus peruvianus 5.22 5.22 1 * -3.2.1.20 maltotetraose ferroplasma acidiphilum 2.8 2.8 1 PMID:15954864 -3.2.1.20 maltotetraose hordeum vulgare 6.98 6.98 1 * -3.2.1.20 maltotetraose panicum miliaceum 40.7 40.7 1 PMID:15845403 -3.2.1.20 maltotetraose schizosaccharomyces pombe 111.0 111.0 1 * -3.2.1.20 maltotetraose solanum tuberosum 74.6 74.6 1 PMID:11469591 -3.2.1.20 maltotetraose sulfolobus acidocaldarius 527.0 527.0 1 PMID:23396915 -3.2.1.20 maltotetraose sulfurisphaera tokodaii 0.03 0.03 1 PMID:23314368 -3.2.1.20 maltotetraose thermoplasma acidophilum 85.5 85.5 1 * -3.2.1.20 maltotriose apis cerana indica 26.6 26.6 1 PMID:23419073 -3.2.1.20 maltotriose apis cerana japonica 15.0 14.0 2 PMID:17151473 -3.2.1.20 maltotriose aspergillus niger 181.0 181.0 1 * -3.2.1.20 maltotriose bifidobacterium longum subsp. longum 103.6 103.6 1 PMID:28283459 -3.2.1.20 maltotriose caldanaerobacter subterraneus subsp. tengcongensis mb4 217.2 217.2 1 PMID:20075617 -3.2.1.20 maltotriose dysdercus peruvianus 6.17 6.17 1 * -3.2.1.20 maltotriose ferroplasma acidiphilum 13.0 13.0 1 PMID:15954864 -3.2.1.20 maltotriose hordeum vulgare 6.65 6.65 1 * -3.2.1.20 maltotriose panicum miliaceum 43.9 43.9 1 PMID:15845403 -3.2.1.20 maltotriose phaffia rhodozyma 8.0 8.0 1 PMID:16491468 -3.2.1.20 maltotriose schizosaccharomyces pombe 994.0 994.0 1 * -3.2.1.20 maltotriose solanum tuberosum 100.4 100.4 1 PMID:11469591 -3.2.1.20 maltotriose sulfolobus acidocaldarius 550.0 550.0 1 PMID:23396915 -3.2.1.20 maltotriose sulfurisphaera tokodaii 0.04 0.04 1 PMID:23314368 -3.2.1.20 maltotriose thermoplasma acidophilum 90.2 90.2 1 * -3.2.1.20 nigerose aspergillus niger 88.4 88.4 1 * -3.2.1.20 nigerose panicum miliaceum 35.7 35.7 1 PMID:15845403 -3.2.1.20 nigerose schizosaccharomyces pombe 435.0 435.0 1 * -3.2.1.20 p-aminophenyl-alpha-d-glucoside dysdercus peruvianus 4.67 4.67 1 * -3.2.1.20 p-nitrophenyl alpha-d-glucopyranoside aspergillus niveus 0.53 0.53 1 PMID:19757138 -3.2.1.20 p-nitrophenyl alpha-d-glucoside apis cerana japonica 13.0 13.0 1 PMID:17151473 -3.2.1.20 p-nitrophenyl-alpha-d-glucopyranoside caldanaerobacter subterraneus subsp. tengcongensis mb4 19.92 19.92 1 PMID:20075617 -3.2.1.20 p-nitrophenyl-alpha-glucoside dysdercus peruvianus 19.0 19.0 1 * -3.2.1.20 panose schizosaccharomyces pombe 704.0 704.0 1 * -3.2.1.20 panose sulfurisphaera tokodaii 0.02 0.02 1 PMID:23314368 -3.2.1.20 panose thermoplasma acidophilum 35.9 35.9 1 * -3.2.1.20 phenyl alpha-glucoside aspergillus niger 1.83 1.83 1 * -3.2.1.20 phenyl alpha-glucoside panicum miliaceum 3.8 3.8 1 PMID:15845403 -3.2.1.20 phenyl alpha-glucoside schizosaccharomyces pombe 1171.0 1171.0 1 * -3.2.1.20 phenyl alpha-maltoside aspergillus niger 181.0 181.0 1 * -3.2.1.20 phenyl alpha-maltoside schizosaccharomyces pombe 1171.0 655.0 2 * -3.2.1.20 phenyl-alpha-d-glucoside dysdercus peruvianus 22.5 22.5 1 * -3.2.1.20 soluble starch apis cerana indica 4.6 4.6 1 PMID:23419073 -3.2.1.20 soluble starch panicum miliaceum 49.7 49.7 1 PMID:15845403 -3.2.1.20 soluble starch phaffia rhodozyma 6.0 4.4350000000000005 2 PMID:16491468 -3.2.1.20 starch aspergillus niger 163.0 163.0 1 * -3.2.1.20 starch aspergillus niveus 24.62 24.62 1 PMID:19757138 -3.2.1.20 sucrose apis cerana indica 845.0 845.0 1 PMID:23419073 -3.2.1.20 sucrose apis cerana japonica 40.0 40.0 1 PMID:17151473 -3.2.1.20 sucrose bacillus sp. (in: firmicutes) 54.6 54.6 1 PMID:7764968 -3.2.1.20 sucrose dysdercus peruvianus 4.07 4.07 1 * -3.2.1.20 sucrose ferroplasma acidiphilum 94.0 94.0 1 PMID:15954864 -3.2.1.20 trehalose thermus thermophilus hb27 343.0 343.0 1 PMID:18223075 -3.2.1.20 turanose dysdercus peruvianus 3.77 3.77 1 * -3.2.1.200 colloidal chitin bacillus licheniformis 5000.0 5000.0 1 PMID:25450539 -3.2.1.203 carboxymethyl cellulose alicyclobacillus acidocaldarius 0.6 0.6 1 PMID:26729722 -3.2.1.203 carboxymethyl cellulose thermoascus aurantiacus 3.98 3.98 1 PMID:22180009 -3.2.1.204 cyclo[(->6)-alpha-d-glc-(1->3)-alpha-d-glc-(1->6)-alpha-d-glc-(->3)-alpha-d-glc-(1->)] bacillus sp. (in: firmicutes) 10.8 10.8 1 PMID:15063208 -3.2.1.204 cyclobis-(1->6)-alpha-nigerosyl kribbella flavida 22.3 22.3 1 PMID:27302067 -3.2.1.204 panose bacillus sp. (in: firmicutes) 14.4 14.4 1 PMID:15063208 -3.2.1.205 isomaltose kribbella flavida 22.0 16.7 2 PMID:27302067;PMID:34665923 -3.2.1.205 isomaltotriose kribbella flavida 1.07 1.07 1 PMID:27302067 -3.2.1.205 panose kribbella flavida 1.17 1.17 1 PMID:27302067 -3.2.1.206 oleuropein saccharolobus solfataricus 350.8 312.4 2 PMID:10682286 -3.2.1.206 oleuropein streptomyces sp. 0.033 0.033 1 PMID:30556012 -3.2.1.207 maltohexaose schizosaccharomyces pombe 0.109 0.109 1 PMID:28471318 -3.2.1.207 maltose schizosaccharomyces pombe 0.241 0.241 1 PMID:28471318 -3.2.1.207 maltotriose apis cerana indica 26.6 26.6 1 PMID:23419073 -3.2.1.207 nigerose schizosaccharomyces pombe 0.102 0.102 1 PMID:28471318 -3.2.1.207 sucrose apis cerana indica 845.0 845.0 1 PMID:23419073 -3.2.1.209 alpha-d-man-(1->2)-alpha-d-man-(1->2)-alpha-d-man-(1->3)-[alpha-d-man-(1->2)-alpha-d-man-(1->3)-[alpha-d-man-(1->2)-alpha-d-man-(1->6)]-alpha-d-man-(1->6)]-alpha-d-man-(1->4)-beta-d-glcnac-(1->4)-beta-d-glcnac-2-pyridylamine homo sapiens 3.7 3.7 2 PMID:15713668;PMID:15911611 -3.2.1.21 2,3-dinitrophenyl-beta-d-glucopyranoside streptomyces sp. 11.7 11.7 1 PMID:11352732 -3.2.1.21 2,4-dihydroxy-1,4-benzoxazin-3-one glucoside lamium galeobdolon 211.1 211.1 1 PMID:30336442 -3.2.1.21 2,4-dinitrophenyl beta-d-glucoside aspergillus niger 422.0 246.5 2 PMID:23201198 -3.2.1.21 2,4-dinitrophenyl-beta-d-glucopyranoside streptomyces sp. 30.4 30.4 1 PMID:11352732 -3.2.1.21 2-chloro-4-nitrophenyl beta-d-glucopyranoside rasamsonia emersonii 14.0 14.0 1 PMID:27377383 -3.2.1.21 2-chloro-4-nitrophenyl-beta-d-glucopyranoside rasamsonia emersonii 14.0 14.0 1 PMID:27377383 -3.2.1.21 2-nitrophenyl beta-1,4-d-galactopyranoside 6-phosphate pyrococcus furiosus 49.0 49.0 1 PMID:10819960 -3.2.1.21 2-nitrophenyl beta-d-glucopyranoside badhamia polycephala 13.0 7.0 2 PMID:18395487 -3.2.1.21 2-nitrophenyl beta-d-glucopyranoside komagataella pastoris 13.7 13.7 1 PMID:16417459 -3.2.1.21 2-nitrophenyl beta-d-glucopyranoside sorghum bicolor 13.8 13.8 1 PMID:12684498 -3.2.1.21 2-nitrophenyl beta-d-glucopyranoside streptomyces sp. 7.72 7.72 1 PMID:11352732 -3.2.1.21 2-nitrophenyl beta-d-glucopyranoside thermosphaera aggregans 439.8 374.4 2 PMID:12859194 -3.2.1.21 2-nitrophenyl beta-d-glucopyranoside zea mays 121.5 70.66499999999999 2 PMID:10748038;PMID:12684498 -3.2.1.21 2-nitrophenyl beta-d-glucoside thermoascus aurantiacus 235.0 235.0 1 PMID:11115405 -3.2.1.21 2-nitrophenyl-beta-d-galactopyranoside pyrococcus furiosus 2050.0 2050.0 1 PMID:10819960 -3.2.1.21 2-nitrophenyl-beta-d-galactopyranoside thermomyces dupontii 304.0 304.0 1 PMID:16446002 -3.2.1.21 2-nitrophenyl-beta-d-galactopyranoside thermus thermophilus 288.3 288.3 1 PMID:21058504 -3.2.1.21 2-nitrophenyl-beta-d-glucopyranoside pyrococcus furiosus 860.0 860.0 1 PMID:10819960 -3.2.1.21 2-nitrophenyl-beta-d-glucopyranoside thermomyces dupontii 308.0 308.0 1 PMID:16446002 -3.2.1.21 3,4-dinitrophenyl beta-d-glucopyranoside streptomyces sp. 18.2 18.2 1 PMID:11352732 -3.2.1.21 3,5-dinitrophenyl-beta-d-glucopyranoside streptomyces sp. 20.5 20.5 1 PMID:11352732 -3.2.1.21 3-nitrophenyl-beta-d-glucopyranoside streptomyces sp. 15.8 15.8 1 PMID:11352732 -3.2.1.21 4-bromophenyl-beta-d-glucopyranoside streptomyces sp. 3.32 3.32 1 PMID:11352732 -3.2.1.21 4-methylumbeliferyl beta-d-glucoside spodoptera frugiperda 0.231 0.231 1 PMID:18422657 -3.2.1.21 4-methylumbelliferyl beta-d-glucopyranoside saccharolobus solfataricus 8.8 8.8 1 PMID:24060745 -3.2.1.21 4-methylumbelliferyl beta-d-glucopyranoside zea mays 30.3 30.3 1 PMID:12684498 -3.2.1.21 4-methylumbelliferyl beta-d-glucoside komagataella pastoris 7.2 7.2 1 PMID:16417459 -3.2.1.21 4-methylumbelliferyl-beta-d-glucopyranoside glycine max 0.05 0.05 1 PMID:11730862 -3.2.1.21 4-methylumbelliferyl-beta-d-glucopyranoside spodoptera frugiperda 1.73 1.73 1 PMID:11342030 -3.2.1.21 4-methylumbelliferyl-beta-d-glucopyranoside streptomyces sp. 11.7 11.7 1 PMID:11352732 -3.2.1.21 4-methylumbelliferyl-beta-d-glucoside zea mays 53.8 53.8 1 PMID:19016858 -3.2.1.21 4-nitrophenyl alpha-d-fucopyranoside thermotoga petrophila 114048.0 114048.0 1 * -3.2.1.21 4-nitrophenyl beta-d-cellobioside putranjiva roxburghii 7.56 7.56 1 * -3.2.1.21 4-nitrophenyl beta-d-cellobioside thermotoga petrophila 83730.2 83730.2 1 * -3.2.1.21 4-nitrophenyl beta-d-fucopyranoside putranjiva roxburghii 14.77 14.05 3 PMID:28500928 -3.2.1.21 4-nitrophenyl beta-d-fucopyranoside thermococcus kodakarensis 322.25 322.25 1 PMID:26138395 -3.2.1.21 4-nitrophenyl beta-d-fucopyranoside uncultured microorganism 600.0 129.5 6 PMID:27092463;PMID:27557720 -3.2.1.21 4-nitrophenyl beta-d-fucoside spodoptera frugiperda 7.14 7.14 1 PMID:18422657 -3.2.1.21 4-nitrophenyl beta-d-galactopyranoside putranjiva roxburghii 7.95 7.39 3 PMID:28500928 -3.2.1.21 4-nitrophenyl beta-d-galactopyranoside thermotoga petrophila 78809.5 78809.5 1 * -3.2.1.21 4-nitrophenyl beta-d-galactopyranoside uncultured microorganism 197.0 128.5 6 PMID:27092463;PMID:27557720 -3.2.1.21 4-nitrophenyl beta-d-galactoside spodoptera frugiperda 0.269 0.269 1 PMID:18422657 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside agrobacterium tumefaciens 334.9 230.0 5 PMID:28873987 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside aspergillus niger 4000.0 4000.0 1 PMID:15555940 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside aspergillus oryzae 370.0 370.0 1 PMID:16650812 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside aspergillus versicolor 1734.83 1567.58 2 PMID:33636259 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside avena sativa 3.9 3.9 1 PMID:15797725 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside bacillus subtilis 3.1 3.1 1 PMID:29093750 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside badhamia polycephala 110.0 61.5 2 PMID:18395487 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside jeotgalibacillus malaysiensis 33.93 33.93 1 PMID:29723622 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside komagataella pastoris 11.6 11.6 1 PMID:16417459 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside mycothermus thermophilus 73.08 40.42 3 PMID:27271847 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside oryza sativa 2.36 2.36 1 PMID:32738438 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside putranjiva roxburghii 12.0 11.7 3 PMID:28500928 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside rasamsonia emersonii 2226.0 1115.7 2 PMID:15555940;PMID:27377383 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside rhizomucor miehei 0.071 0.071 1 PMID:25577102 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside thermococcus kodakarensis 227.64 227.64 1 PMID:26138395 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside thermofilum pendens 0.577 0.577 1 PMID:23266119 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside thermomyces lanuginosus 44.4 44.4 1 * -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside thermotoga neapolitana 485.0 129.0 3 PMID:20138890;PMID:28142197 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside thermotoga petrophila 1214290.0 51.43 3 * -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside trichoderma reesei 8664.0 8664.0 1 PMID:15555940 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside uncultured microorganism 286.0 91.1 7 PMID:27092463;PMID:27557720 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside weissella cibaria 30.63 30.63 1 PMID:23221534 -3.2.1.21 4-nitrophenyl beta-d-glucopyranoside zea mays 29.5 26.83 2 PMID:10748038;PMID:12684498 -3.2.1.21 4-nitrophenyl beta-d-glucoside aspergillus niger 141.0 141.0 1 PMID:23201198 -3.2.1.21 4-nitrophenyl beta-d-glucoside saccharolobus solfataricus 9.15 9.15 1 PMID:24060745 -3.2.1.21 4-nitrophenyl beta-d-glucoside spodoptera frugiperda 2.26 2.26 1 PMID:18422657 -3.2.1.21 4-nitrophenyl beta-d-glucoside thermoascus aurantiacus 242.0 116.6 3 PMID:11115405 -3.2.1.21 4-nitrophenyl beta-d-mannopyranoside thermococcus kodakarensis 50.99 50.99 1 PMID:26138395 -3.2.1.21 4-nitrophenyl beta-d-xylopyranoside thermotoga petrophila 232540.0 232540.0 1 * -3.2.1.21 4-nitrophenyl beta-d-xyloside spodoptera frugiperda 0.0302 0.0302 1 PMID:18422657 -3.2.1.21 4-nitrophenyl beta-l-arabinopyranoside homo sapiens 0.29 0.29 1 PMID:17555766 -3.2.1.21 4-nitrophenyl-alpha-l-arabino-pyranoside homo sapiens 1.88 1.88 1 PMID:17555766 -3.2.1.21 4-nitrophenyl-alpha-l-arabinopyranoside agrobacterium tumefaciens 119.0 119.0 1 * -3.2.1.21 4-nitrophenyl-alpha-l-arabinopyranoside thermotoga maritima 9.0 9.0 1 * -3.2.1.21 4-nitrophenyl-beta-d-cellobioside thermotoga petrophila 17500.0 17500.0 1 PMID:22714267 -3.2.1.21 4-nitrophenyl-beta-d-fucopyranoside agrobacterium tumefaciens 22.1 22.1 1 * -3.2.1.21 4-nitrophenyl-beta-d-fucopyranoside caldicellulosiruptor saccharolyticus 516.0 516.0 1 PMID:19577189 -3.2.1.21 4-nitrophenyl-beta-d-fucopyranoside homo sapiens 3.13 3.13 1 PMID:17555766 -3.2.1.21 4-nitrophenyl-beta-d-fucopyranoside oryza sativa 33.5 33.5 1 PMID:19587102 -3.2.1.21 4-nitrophenyl-beta-d-fucopyranoside thermoplasma acidophilum 182.0 182.0 1 PMID:19458917 -3.2.1.21 4-nitrophenyl-beta-d-fucopyranoside thermotoga maritima 27.7 27.7 1 * -3.2.1.21 4-nitrophenyl-beta-d-fucoside spodoptera frugiperda 3.3 3.3 1 PMID:20027479 -3.2.1.21 4-nitrophenyl-beta-d-galactopyranoside caldicellulosiruptor saccharolyticus 82.0 82.0 1 PMID:19577189 -3.2.1.21 4-nitrophenyl-beta-d-galactopyranoside homo sapiens 5.53 5.53 1 PMID:17555766 -3.2.1.21 4-nitrophenyl-beta-d-galactopyranoside oryza sativa 9.8 9.8 1 PMID:19587102 -3.2.1.21 4-nitrophenyl-beta-d-galactopyranoside phanerodontia chrysosporium 67.6 5.5600000000000005 4 PMID:16896601 -3.2.1.21 4-nitrophenyl-beta-d-galactopyranoside thermoplasma acidophilum 27.0 27.0 1 PMID:19458917 -3.2.1.21 4-nitrophenyl-beta-d-galactopyranoside thermus thermophilus 167.4 167.4 1 PMID:21058504 -3.2.1.21 4-nitrophenyl-beta-d-galactoside spodoptera frugiperda 0.35 0.35 1 PMID:20027479 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside agrobacterium tumefaciens 95.4 95.4 1 * -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside aspergillus japonicus 259.0 259.0 1 PMID:19538132 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside aspergillus niger 89.0 66.7 3 PMID:17067546;PMID:20181208;PMID:9438354 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside avena sativa 2.0 1.6 2 PMID:19100871 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside caldicellulosiruptor saccharolyticus 387.0 387.0 1 PMID:19577189 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside cellulomonas gilvus 42.2 5.62 3 * -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside fomitopsis palustris 721.0 721.0 1 PMID:18337693 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside halalkalibacterium halodurans 0.75 0.75 1 PMID:20618142 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside homo sapiens 3.12 3.12 1 PMID:17555766 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside melanocarpus sp. 66.67 66.67 1 * -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside mycothermus thermophilus 343.5 343.5 1 * -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside oryza sativa 38.9 21.794999999999998 2 PMID:18308333;PMID:19587102 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside paecilomyces sp. 'thermophila' 13.0 13.0 1 PMID:18092750 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside penicillium brasilianum 118.0 118.0 1 PMID:19756584 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside phanerodontia chrysosporium 20.8 9.35 3 PMID:16896601 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside pholiota adiposa 3460.0 3460.0 1 * -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside phoma sp. 0.5 0.5 1 PMID:21617347 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside plumeria obtusa 30.7 30.7 1 PMID:16894479 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside stachybotrys sp. 915.0 915.0 1 PMID:17938914 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside talaromyces verruculosus 160.0 160.0 1 PMID:19538132 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside thermomyces lanuginosus 44.4 44.4 1 * -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside thermoplasma acidophilum 141.0 141.0 1 PMID:19458917 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside thermotoga maritima 6.4 6.01 4 * -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside thermotoga petrophila 87400.0 87400.0 1 PMID:22714267 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside thermus thermophilus 32.3 27.65 2 PMID:10580648;PMID:21058504 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside trichoderma reesei 144.0 128.0 4 PMID:1599951;PMID:19538132;PMID:20181208 -3.2.1.21 4-nitrophenyl-beta-d-glucopyranoside verruciconidia persicina 640.0 640.0 1 PMID:9291624 -3.2.1.21 4-nitrophenyl-beta-d-glucoside listeria innocua clip11262 48.0 48.0 1 PMID:26886583 -3.2.1.21 4-nitrophenyl-beta-d-glucoside zea mays 42.8 42.8 1 PMID:19016858 -3.2.1.21 4-nitrophenyl-beta-d-mannopyranoside thermoplasma acidophilum 14.0 14.0 1 PMID:19458917 -3.2.1.21 4-nitrophenyl-beta-d-xylopyranoside agrobacterium tumefaciens 28.9 28.9 1 * -3.2.1.21 4-nitrophenyl-beta-d-xylopyranoside phanerodontia chrysosporium 0.384 0.384 1 PMID:16896601 -3.2.1.21 4-nitrophenyl-beta-d-xylopyranoside thermotoga maritima 18.4 18.4 1 * -3.2.1.21 4-nitrophenyl-beta-d-xylopyranoside thermotoga petrophila 5300.0 5300.0 1 PMID:22714267 -3.2.1.21 4-nitrophenyl-beta-d-xyloside mycothermus thermophilus 10.2 10.2 1 * -3.2.1.21 4-o-alpha-d-mannopyranosyl-d-mannopyranose thermofilum pendens 0.038 0.038 1 PMID:23266119 -3.2.1.21 6-o-methyl-n-deacetylipecoside carapichea ipecacuanha 31.1 31.1 1 PMID:18927081 -3.2.1.21 amygdalin paecilomyces sp. 'thermophila' 7.9 7.9 1 PMID:18092750 -3.2.1.21 amygdalin spodoptera frugiperda 0.32 0.32 1 PMID:11342030 -3.2.1.21 apigenin-7-beta-d-glucopyranoside homo sapiens 1.53 1.53 1 PMID:11784319 -3.2.1.21 apigenin-7-o-beta-d-glucopyranoside pseudomonas sp. 3.92 3.92 1 PMID:15053533 -3.2.1.21 apigenin-7-o-beta-d-glucoside homo sapiens 0.77 0.77 1 PMID:17555766 -3.2.1.21 apigetrin penicillium decumbens 0.6 0.385 2 * -3.2.1.21 arbutin glycine max 0.15 0.15 1 PMID:11730862 -3.2.1.21 arbutin penicillium decumbens 0.1 0.065 2 * -3.2.1.21 arbutin pseudomonas sp. 1.06 1.06 1 PMID:15053533 -3.2.1.21 avenacoside avena sativa 443.0 402.0 3 PMID:15797725;PMID:19100871 -3.2.1.21 beta-beta-trehalose thermoascus aurantiacus 284.0 284.0 1 PMID:11115405 -3.2.1.21 beta-d-glucan oryza sativa 1.07 1.07 1 PMID:32738438 -3.2.1.21 beta-gentiobiose aspergillus oryzae 950.0 950.0 1 PMID:16650812 -3.2.1.21 cellobiose agrobacterium tumefaciens 233.0 233.0 1 PMID:28873987 -3.2.1.21 cellobiose aspergillus japonicus 350.0 350.0 1 PMID:19538132 -3.2.1.21 cellobiose aspergillus niger 103.0 67.4 3 PMID:17067546;PMID:20181208;PMID:23201198 -3.2.1.21 cellobiose aspergillus oryzae 1000.0 1000.0 1 PMID:16650812 -3.2.1.21 cellobiose badhamia polycephala 103.0 70.0 2 PMID:18395487 -3.2.1.21 cellobiose cerrena unicolor 35.0 35.0 1 PMID:29418014 -3.2.1.21 cellobiose fomitopsis palustris 101.8 101.8 1 PMID:18337693 -3.2.1.21 cellobiose halothermothrix orenii 387.0 387.0 1 PMID:26621798 -3.2.1.21 cellobiose mycothermus thermophilus 3132.0 1652.05 2 * -3.2.1.21 cellobiose oryza sativa 1.16 0.634 3 PMID:18308333;PMID:19587102;PMID:32738438 -3.2.1.21 cellobiose paecilomyces sp. 'thermophila' 4.5 4.5 1 PMID:18092750 -3.2.1.21 cellobiose penicillium brasilianum 43.0 43.0 1 PMID:19756584 -3.2.1.21 cellobiose penicillium decumbens 0.5 0.3 2 * -3.2.1.21 cellobiose phanerodontia chrysosporium 181.0 29.8 3 PMID:12619666;PMID:18023045 -3.2.1.21 cellobiose phoma sp. 699.0 699.0 1 PMID:21617347 -3.2.1.21 cellobiose prunus armeniaca 144.8 144.8 1 * -3.2.1.21 cellobiose putranjiva roxburghii 8.12 7.88 3 PMID:28500928 -3.2.1.21 cellobiose pyrococcus furiosus 594.0 594.0 1 PMID:20519912 -3.2.1.21 cellobiose rasamsonia emersonii 55.0 30.25 2 PMID:27377383 -3.2.1.21 cellobiose rhizomucor miehei 0.043 0.043 1 PMID:25577102 -3.2.1.21 cellobiose saccharolobus solfataricus 1.8 1.8 1 PMID:24060745 -3.2.1.21 cellobiose schwanniomyces etchellsii 233.0 233.0 1 PMID:12818193 -3.2.1.21 cellobiose spodoptera frugiperda 0.5 0.5 1 PMID:11342030 -3.2.1.21 cellobiose stereum hirsutum 281.0 281.0 1 PMID:23462008 -3.2.1.21 cellobiose streptomyces sp. 35.6 35.6 1 PMID:11352732 -3.2.1.21 cellobiose talaromyces verruculosus 89.0 89.0 1 PMID:19538132 -3.2.1.21 cellobiose thermoascus aurantiacus 284.0 284.0 1 PMID:11115405 -3.2.1.21 cellobiose thermofilum pendens 0.317 0.317 1 PMID:23266119 -3.2.1.21 cellobiose thermomyces dupontii 167.0 167.0 1 PMID:16446002 -3.2.1.21 cellobiose thermotoga petrophila 1469.8 1469.8 1 * -3.2.1.21 cellobiose trichoderma reesei 51.5 41.375 4 PMID:1599951;PMID:19538132;PMID:20181208 -3.2.1.21 cellohexaose badhamia polycephala 8.0 6.5 2 PMID:18395487 -3.2.1.21 cellopentaose aspergillus niger 51.7 51.7 1 PMID:17067546 -3.2.1.21 cellotetraose aspergillus niger 54.7 54.7 1 PMID:17067546 -3.2.1.21 cellotetraose rhizomucor miehei 0.059 0.059 1 PMID:25577102 -3.2.1.21 cellotriose aspergillus niger 85.1 44.4 2 PMID:17067546 -3.2.1.21 cellotriose oryza sativa 2.35 1.875 2 PMID:18308333;PMID:32738438 -3.2.1.21 cellotriose rasamsonia emersonii 0.72 0.72 1 PMID:27377383 -3.2.1.21 cellotriose rhizomucor miehei 0.067 0.067 1 PMID:25577102 -3.2.1.21 d-cellobiose thermobifida fusca 16.3 16.3 1 PMID:16269126 -3.2.1.21 daidzein 7'-o-(6''-o-beta-d-malonyl-beta-d-glucoside) glycine max 46.0 25.17 2 PMID:11730862;PMID:16891302 -3.2.1.21 daidzein 7'-o-beta-d-glucoside glycine max 22.0 22.0 1 PMID:16891302 -3.2.1.21 daidzein 7-o-(6''-o-beta-d-malonyl-beta-d-glucoside) homo sapiens 0.24 0.24 1 PMID:11784319 -3.2.1.21 daidzein 7-o-(6-o-malonyl-beta-d-glucoside) pseudomonas sp. 2.39 2.39 1 PMID:15053533 -3.2.1.21 daidzein 7-o-beta-d-glucopyranoside homo sapiens 3.55 3.55 1 PMID:12667141 -3.2.1.21 daidzein-7-beta-d-glucopyranoside homo sapiens 3.55 3.55 1 PMID:11784319 -3.2.1.21 daidzein-7-beta-d-glucopyranoside pseudomonas sp. 5.12 5.12 1 PMID:15053533 -3.2.1.21 daidzein-7-o-glucoside glycine max 3.07 3.07 1 PMID:11730862 -3.2.1.21 daidzin penicillium decumbens 0.4 0.30000000000000004 2 * -3.2.1.21 daidzin saccharolobus solfataricus 2532.0 2532.0 1 PMID:21898127 -3.2.1.21 daidzin thermoascus aurantiacus 79.8 71.55 2 * -3.2.1.21 dhurrin lamium galeobdolon 112.5 112.5 1 PMID:30336442 -3.2.1.21 dhurrin sorghum bicolor 77.7 46.0 2 PMID:10748038;PMID:12684498 -3.2.1.21 eriodictyol-7-beta-d-glucopyranoside homo sapiens 1.26 1.26 2 PMID:11784319;PMID:12667141 -3.2.1.21 eriodictyol-7-glucoside homo sapiens 0.73 0.73 1 PMID:17555766 -3.2.1.21 esculin glycine max 0.02 0.02 1 PMID:11730862 -3.2.1.21 esculin pseudomonas sp. 1.57 1.57 1 PMID:15053533 -3.2.1.21 genistein 7-o-(6''-o-malonyl-beta-d-glucoside) glycine max 98.0 98.0 1 PMID:16891302 -3.2.1.21 genistein 7-o-beta-d-glucoside glycine max 13.0 13.0 1 PMID:16891302 -3.2.1.21 genistein-7-beta-d-glucopyranoside homo sapiens 1.53 1.53 1 PMID:11784319 -3.2.1.21 genistein-7-beta-d-glucopyranoside pseudomonas sp. 5.31 5.31 1 PMID:15053533 -3.2.1.21 genistein-7-beta-d-glucosyl-6''-o-malonate pseudomonas sp. 2.68 2.68 1 PMID:15053533 -3.2.1.21 genistein-7-o-glucoside glycine max 4.45 4.45 1 PMID:11730862 -3.2.1.21 genistein-7-o-glucosyl-6''-o-malonate glycine max 4.38 4.38 1 PMID:11730862 -3.2.1.21 genistin thermoascus aurantiacus 171.2 122.05 2 * -3.2.1.21 gentiobiose aspergillus niger 70.0 70.0 1 PMID:17067546 -3.2.1.21 gentiobiose badhamia polycephala 20.0 18.5 2 PMID:18395487 -3.2.1.21 gentiobiose oryza sativa 0.17 0.17 1 PMID:19587102 -3.2.1.21 gentiobiose paecilomyces sp. 'thermophila' 4.2 4.2 1 PMID:18092750 -3.2.1.21 gentiobiose penicillium decumbens 0.6 0.5 2 * -3.2.1.21 gentiobiose spodoptera frugiperda 0.6 0.6 1 PMID:11342030 -3.2.1.21 gentiobiose thermoascus aurantiacus 141.0 141.0 1 PMID:11115405 -3.2.1.21 gentobiose rhizomucor miehei 0.056 0.056 1 PMID:25577102 -3.2.1.21 glycitin thermoascus aurantiacus 95.8 79.85 2 * -3.2.1.21 ipecoside carapichea ipecacuanha 51.6 51.6 1 PMID:18927081 -3.2.1.21 lactose halothermothrix orenii 366.0 366.0 1 PMID:26621798 -3.2.1.21 laminaran rhizomucor miehei 0.033 0.033 1 PMID:25577102 -3.2.1.21 laminaribiose aspergillus oryzae 930.0 930.0 1 PMID:16650812 -3.2.1.21 laminaribiose listeria innocua clip11262 23.0 23.0 1 PMID:26886583 -3.2.1.21 laminaribiose oryza sativa 6.17 4.1 2 PMID:19587102;PMID:32738438 -3.2.1.21 laminaribiose rhizomucor miehei 0.078 0.078 1 PMID:25577102 -3.2.1.21 laminarin oryza sativa 0.428 0.428 1 PMID:32738438 -3.2.1.21 laminaripentaose listeria innocua clip11262 12.0 12.0 1 PMID:26886583 -3.2.1.21 laminaritetraose listeria innocua clip11262 14.0 14.0 1 PMID:26886583 -3.2.1.21 laminaritriose listeria innocua clip11262 11.0 11.0 1 PMID:26886583 -3.2.1.21 laminaritriose oryza sativa 1.7 1.67 2 PMID:19587102;PMID:32738438 -3.2.1.21 laminaritriose rhizomucor miehei 0.077 0.077 1 PMID:25577102 -3.2.1.21 lichenan oryza sativa 2.92 2.92 1 PMID:32738438 -3.2.1.21 luteolin-4'-beta-d-glucopyranoside homo sapiens 1.17 1.17 2 PMID:11784319;PMID:12667141 -3.2.1.21 luteolin-7-beta-d-glucopyranoside homo sapiens 3.05 3.05 2 PMID:11784319;PMID:12667141 -3.2.1.21 n,n'-diacetyl-beta-chitobiose saccharolobus solfataricus 0.56 0.56 1 PMID:24060745 -3.2.1.21 n-deacetylipecoside carapichea ipecacuanha 28.2 28.2 1 PMID:18927081 -3.2.1.21 n-heptyl-beta-d-glucoside oryza sativa 4.25 4.25 1 PMID:19587102 -3.2.1.21 n-octyl beta-d-glucoside thermoascus aurantiacus 235.0 235.0 1 PMID:11115405 -3.2.1.21 naringenin penicillium decumbens 0.6 0.395 2 * -3.2.1.21 naringenin-7-beta-d-glucopyranoside homo sapiens 2.6 2.6 2 PMID:11784319;PMID:12667141 -3.2.1.21 naringenin-7-glucoside homo sapiens 1.4 1.4 1 PMID:17555766 -3.2.1.21 o-nitrophenyl-beta-d-glucopyranoside glycine max 1.4 1.4 1 PMID:11730862 -3.2.1.21 octyl-beta-d-glucopyranoside spodoptera frugiperda 0.06 0.06 1 PMID:11342030 -3.2.1.21 oleuropein lamium galeobdolon 104.4 104.4 1 PMID:30336442 -3.2.1.21 p-nitrophenyl-alpha-d-galactopyranoside glycine max 0.49 0.49 1 PMID:11730862 -3.2.1.21 p-nitrophenyl-alpha-d-mannopyranoside glycine max 0.1 0.1 1 PMID:11730862 -3.2.1.21 p-nitrophenyl-alpha-l-arabinopyranoside homo sapiens 5.97 5.97 1 PMID:11784319 -3.2.1.21 p-nitrophenyl-beta-d-arabinopyranoside homo sapiens 6.0 6.0 1 PMID:12667141 -3.2.1.21 p-nitrophenyl-beta-d-fucopyranoside homo sapiens 10.7 10.7 2 PMID:11784319;PMID:12667141 -3.2.1.21 p-nitrophenyl-beta-d-fucopyranoside spodoptera frugiperda 2.4 2.4 1 PMID:11342030 -3.2.1.21 p-nitrophenyl-beta-d-fucopyranoside streptomyces sp. 37.1 37.1 1 PMID:11352732 -3.2.1.21 p-nitrophenyl-beta-d-galactopyranoside glycine max 0.93 0.93 1 PMID:11730862 -3.2.1.21 p-nitrophenyl-beta-d-galactopyranoside homo sapiens 17.6 17.6 2 PMID:11784319;PMID:12667141 -3.2.1.21 p-nitrophenyl-beta-d-galactopyranoside pseudomonas sp. 0.62 0.62 1 PMID:15053533 -3.2.1.21 p-nitrophenyl-beta-d-galactopyranoside spodoptera frugiperda 0.17 0.17 1 PMID:11342030 -3.2.1.21 p-nitrophenyl-beta-d-galactopyranoside streptomyces sp. 118.0 118.0 1 PMID:11352732 -3.2.1.21 p-nitrophenyl-beta-d-glucopyranoside glycine max 0.11 0.11 1 PMID:11730862 -3.2.1.21 p-nitrophenyl-beta-d-glucopyranoside homo sapiens 12.1 12.1 2 PMID:11784319;PMID:12667141 -3.2.1.21 p-nitrophenyl-beta-d-glucopyranoside penicillium decumbens 1.5 0.9299999999999999 2 * -3.2.1.21 p-nitrophenyl-beta-d-glucopyranoside pseudomonas sp. 0.87 0.87 1 PMID:15053533 -3.2.1.21 p-nitrophenyl-beta-d-glucopyranoside schwanniomyces etchellsii 170.0 155.5 2 PMID:12818193 -3.2.1.21 p-nitrophenyl-beta-d-glucopyranoside spodoptera frugiperda 0.56 0.56 1 PMID:11342030 -3.2.1.21 p-nitrophenyl-beta-d-glucopyranoside streptomyces sp. 28.4 18.27 2 PMID:11352732 -3.2.1.21 p-nitrophenyl-beta-d-glucose phanerodontia chrysosporium 103.1 99.65 2 PMID:12619666 -3.2.1.21 p-nitrophenyl-beta-d-mannopyranoside pseudomonas sp. 0.32 0.32 1 PMID:15053533 -3.2.1.21 p-nitrophenyl-beta-d-xylopyranoside homo sapiens 0.75 0.75 1 PMID:11784319 -3.2.1.21 p-nitrophenyl-beta-d-xylopyranoside spodoptera frugiperda 0.01 0.01 1 PMID:11342030 -3.2.1.21 p-nitrophenyl-beta-l-arabinopyranoside homo sapiens 0.66 0.66 1 PMID:11784319 -3.2.1.21 phenyl-beta-d-glucopyranoside streptomyces sp. 0.66 0.66 1 PMID:11352732 -3.2.1.21 plumieride coumarate beta-d-glucoside plumeria obtusa 13.9 13.9 1 PMID:16894479 -3.2.1.21 polydatin unidentified microorganism 989.0 989.0 1 * -3.2.1.21 quercetin 3-o-beta-d-glucopyranoside thermotoga neapolitana 13.6 13.6 1 PMID:28142197 -3.2.1.21 quercetin-3,4'-di-beta-d-glucopyranoside homo sapiens 0.3 0.3 1 PMID:11784319 -3.2.1.21 quercetin-4'-beta-d-glucopyranoside homo sapiens 1.08 1.08 2 PMID:11784319;PMID:12667141 -3.2.1.21 quercetin-4'-o-beta-d-glucoside homo sapiens 1.5 1.5 1 PMID:17555766 -3.2.1.21 quercetin-7-beta-d-glucopyranoside homo sapiens 0.69 0.69 2 PMID:11784319;PMID:12667141 -3.2.1.21 quercetin-7-o-beta-d-glucoside homo sapiens 0.6 0.6 1 PMID:17555766 -3.2.1.21 salicin glycine max 0.21 0.21 1 PMID:11730862 -3.2.1.21 salicin mycothermus thermophilus 404.8 404.8 1 * -3.2.1.21 salicin paecilomyces sp. 'thermophila' 7.1 7.1 1 PMID:18092750 -3.2.1.21 salicin penicillium decumbens 0.7 0.39999999999999997 2 * -3.2.1.21 salicin pseudomonas sp. 1.32 1.32 1 PMID:15053533 -3.2.1.21 sophoropentaose listeria innocua clip11262 1.0 1.0 1 PMID:26886583 -3.2.1.21 sophorose aspergillus oryzae 820.0 820.0 1 PMID:16650812 -3.2.1.21 sophorose listeria innocua clip11262 41.0 41.0 1 PMID:26886583 -3.2.1.21 sophorose oryza sativa 9.8 9.8 1 PMID:19587102 -3.2.1.21 sophorose paecilomyces sp. 'thermophila' 3.7 3.7 1 PMID:18092750 -3.2.1.21 sophorose thermoascus aurantiacus 136.0 136.0 1 PMID:11115405 -3.2.1.21 sophorotetraose listeria innocua clip11262 3.5 3.5 1 PMID:26886583 -3.2.1.21 sophorotriose listeria innocua clip11262 56.0 56.0 1 PMID:26886583 -3.2.1.21 strictosidine carapichea ipecacuanha 2.1 2.1 1 PMID:18927081 -3.2.1.21 vincoside carapichea ipecacuanha 6.4 6.4 1 PMID:18927081 -3.2.1.211 kjellmaniella crassifolia fucoidan alteromonas sp. sn-1009 0.0137 0.0137 1 PMID:33725543 -3.2.1.213 beta-d-gal(1->6)-beta-d-gal-(1->6)-d-gal bifidobacterium longum subsp. longum 261.0 261.0 1 PMID:30564851 -3.2.1.214 beta-1,2-glucan parabacteroides distasonis 0.48 0.48 1 PMID:29763309 -3.2.1.214 beta-1,2-glucopentasaccharide parabacteroides distasonis 29.0 29.0 1 PMID:29763309 -3.2.1.214 beta-1,2-glucotetrasaccharide parabacteroides distasonis 54.0 54.0 1 PMID:29763309 -3.2.1.215 alpha-d-galp-(1->3)-alpha-l-araf-ome bifidobacterium longum subsp. longum 199.0 199.0 1 PMID:33674431 -3.2.1.215 beta-l-arap-(1->3)-alpha-l-araf-ome bifidobacterium longum subsp. longum 12.1 12.1 1 PMID:33674431 -3.2.1.216 6-o-alpha-kojibiosylglucose flavobacterium johnsoniae 72.8 72.8 1 PMID:34728215 -3.2.1.216 6-o-alpha-kojitriosylglucose flavobacterium johnsoniae 59.3 59.3 1 PMID:34728215 -3.2.1.216 alpha-d-glucopyranosyl fluoride flavobacterium johnsoniae 56.1 56.1 1 PMID:34728215 -3.2.1.216 kojibiose flavobacterium johnsoniae 108.0 108.0 1 PMID:34728215 -3.2.1.216 kojibiose mucilaginibacter mallensis 9.9 9.9 1 PMID:34684901 -3.2.1.216 kojipentaose flavobacterium johnsoniae 44.5 44.5 1 PMID:34728215 -3.2.1.216 kojitetraose flavobacterium johnsoniae 67.5 67.5 1 PMID:34728215 -3.2.1.216 kojitriose flavobacterium johnsoniae 46.5 46.5 1 PMID:34728215 -3.2.1.217 4-nitrophenyl alpha-n-acetyl-d-galactosaminide bacteroides caccae 3.6 2.85 2 PMID:31530641 -3.2.1.217 4-nitrophenyl alpha-n-acetyl-d-galactosaminide bombyx mori 3.23 3.23 1 PMID:33742736 -3.2.1.217 4-nitrophenyl alpha-n-acetyl-d-galactosaminide enterococcus faecalis 6.54 6.54 3 PMID:32367553;PMID:34826537 -3.2.1.217 4-nitrophenyl alpha-n-acetyl-d-galactosaminide phocaeicola plebeius 7.2 4.71 2 PMID:31530641 -3.2.1.22 1-naphthyl alpha-d-galactoside phanerodontia chrysosporium 171.0 171.0 1 PMID:10085226 -3.2.1.22 2,4-dinitrophenyl alpha-d-galactoside thermotoga maritima 12.23 6.32 2 PMID:17323919 -3.2.1.22 2,5-dinitrophenyl alpha-d-galactoside thermotoga maritima 11.2 11.2 1 PMID:17323919 -3.2.1.22 2-nitrophenyl alpha-d-galactopyranoside phanerodontia chrysosporium 514.0 514.0 1 PMID:10085226 -3.2.1.22 2-nitrophenyl alpha-d-galactopyranoside phaseolus vulgaris 0.238 0.238 1 PMID:7703901 -3.2.1.22 2-nitrophenyl alpha-d-galactoside thermotoga maritima 13.67 7.095 2 PMID:17323919 -3.2.1.22 3,4-dimethylphenyl alpha-d-galactoside thermotoga maritima 10.39 6.245 2 PMID:17323919 -3.2.1.22 3-nitrophenyl alpha-d-galactopyranoside phaseolus vulgaris 0.822 0.822 1 PMID:7703901 -3.2.1.22 3-nitrophenyl alpha-d-galactoside thermotoga maritima 10.5 10.5 1 PMID:17323919 -3.2.1.22 4-bromophenyl alpha-d-galactoside thermotoga maritima 12.58 12.58 1 PMID:17323919 -3.2.1.22 4-methylumbelliferyl alpha-d-galactoside thermomyces lanuginosus 49.8 49.8 1 PMID:11078955 -3.2.1.22 4-nitrophenyl alpha-d-galactopyranoside acinetobacter sp. 7.42 4.975 2 PMID:28324395 -3.2.1.22 4-nitrophenyl alpha-d-galactopyranoside geobacillus stearothermophilus 2382.0 1243.8 2 PMID:23012371 -3.2.1.22 4-nitrophenyl alpha-d-galactopyranoside penicillium canescens 1800.0 903.5 2 PMID:18294137 -3.2.1.22 4-nitrophenyl alpha-d-galactopyranoside phanerodontia chrysosporium 272.0 272.0 1 PMID:10085226 -3.2.1.22 4-nitrophenyl alpha-d-galactopyranoside phaseolus vulgaris 3.61 3.61 1 PMID:7703901 -3.2.1.22 4-nitrophenyl alpha-d-galactopyranoside rhizomucor miehei 6.3 6.3 1 PMID:22349190 -3.2.1.22 4-nitrophenyl alpha-d-galactopyranoside sphingomonas sp. 512.0 512.0 1 PMID:23124345 -3.2.1.22 4-nitrophenyl alpha-d-galactopyranoside thermotoga maritima 65.0 36.5 2 PMID:21084405;PMID:24237145 -3.2.1.22 4-nitrophenyl alpha-d-galactoside bacteroides thetaiotaomicron 244.0 244.0 1 PMID:19646996 -3.2.1.22 4-nitrophenyl alpha-d-galactoside thermotoga maritima 8.58 8.58 1 PMID:17323919 -3.2.1.22 4-nitrophenyl alpha-d-galactoside yersinia pestis 3279.0 3279.0 1 PMID:18685186 -3.2.1.22 4-nitrophenyl-alpha-d-galactopyranoside aspergillus nidulans 1278.0 1278.0 1 PMID:20681989 -3.2.1.22 4-nitrophenyl-alpha-d-galactopyranoside citrobacter freundii 2.07 1.05 9 PMID:21495656 -3.2.1.22 4-nitrophenyl-alpha-d-galactopyranoside debaryomyces hansenii 3.29 3.29 1 PMID:19226141 -3.2.1.22 4-nitrophenyl-alpha-d-galactopyranoside flavobacterium sp. 654.6 654.6 1 PMID:20714719 -3.2.1.22 4-nitrophenyl-alpha-d-galactopyranoside saccharomyces cerevisiae 286.0 286.0 1 PMID:20592022 -3.2.1.22 4-o-methylphenyl alpha-d-galactoside thermotoga maritima 6.69 3.62 2 PMID:17323919 -3.2.1.22 6-bromo-2-naphthyl alpha-d-galactoside phanerodontia chrysosporium 77.0 77.0 1 PMID:10085226 -3.2.1.22 alpha-d-gal-(1->3)-l-ara bifidobacterium longum subsp. longum 107.0 107.0 1 PMID:34429699 -3.2.1.22 alpha-d-galactosyl fluoride phanerodontia chrysosporium 87.0 87.0 1 PMID:10085226 -3.2.1.22 beta-naphthyl alpha-d-galactoside thermotoga maritima 6.26 6.26 1 PMID:17323919 -3.2.1.22 galactomannan with galactose/mannose ratio 1:1.72 penicillium canescens 7.0 7.0 1 PMID:18294137 -3.2.1.22 galactomannan with galactose/mannose ratio 1:2.4 penicillium canescens 10.0 10.0 1 PMID:18294137 -3.2.1.22 melibiose aspergillus nidulans 1067.0 1067.0 1 PMID:20681989 -3.2.1.22 melibiose debaryomyces hansenii 0.03 0.03 1 PMID:19226141 -3.2.1.22 melibiose flavobacterium sp. 2.33 2.33 1 PMID:20714719 -3.2.1.22 melibiose rhizomucor miehei 0.65 0.65 1 PMID:22349190 -3.2.1.22 melibiose saccharomyces cerevisiae 193.0 193.0 1 PMID:20592022 -3.2.1.22 melibiose sphingomonas sp. 448.0 448.0 1 PMID:23124345 -3.2.1.22 melibiose thermomyces lanuginosus 2.3 2.3 1 PMID:11078955 -3.2.1.22 melibiose thermotoga neapolitana 234.2 234.2 1 PMID:11210503 -3.2.1.22 p-nitrophenyl alpha-d-galactopyranoside thermomyces lanuginosus 3914.0 3914.0 1 PMID:17008008 -3.2.1.22 p-nitrophenyl alpha-d-galactopyranoside thermotoga maritima 176.0 176.0 1 PMID:11210503 -3.2.1.22 p-nitrophenyl alpha-d-galactopyranoside thermotoga neapolitana 302.9 302.9 1 PMID:11210503 -3.2.1.22 phenyl alpha-d-galactoside thermotoga maritima 5.71 5.71 1 PMID:17323919 -3.2.1.22 raffinose acinetobacter sp. 1.83 1.415 2 PMID:28324395 -3.2.1.22 raffinose aspergillus nidulans 586.0 586.0 1 PMID:20681989 -3.2.1.22 raffinose bifidobacterium longum subsp. longum 270.0 270.0 1 PMID:34429699 -3.2.1.22 raffinose debaryomyces hansenii 4.12 4.12 1 PMID:19226141 -3.2.1.22 raffinose geobacillus stearothermophilus 1205.0 692.5 2 PMID:23012371 -3.2.1.22 raffinose penicillium canescens 1100.0 550.445 2 PMID:18294137 -3.2.1.22 raffinose rhizomucor miehei 4.2 4.2 1 PMID:22349190 -3.2.1.22 raffinose saccharomyces cerevisiae 46.8 46.8 1 PMID:20592022 -3.2.1.22 raffinose thermomyces lanuginosus 6946.0 3489.2 2 PMID:11078955;PMID:17008008 -3.2.1.22 raffinose thermotoga maritima 109.0 109.0 1 PMID:11210503 -3.2.1.22 raffinose thermotoga neapolitana 157.3 157.3 1 PMID:11210503 -3.2.1.22 stachyose debaryomyces hansenii 6.05 6.05 1 PMID:19226141 -3.2.1.22 stachyose flavobacterium sp. 42.04 42.04 1 PMID:20714719 -3.2.1.22 stachyose penicillium canescens 1250.0 625.285 2 PMID:18294137 -3.2.1.22 stachyose rhizomucor miehei 6.4 6.4 1 PMID:22349190 -3.2.1.22 stachyose thermomyces lanuginosus 7659.0 7659.0 1 PMID:17008008 -3.2.1.220 1alpha(s)-6-o-methyl-n-deacetylisoipecoside carapichea ipecacuanha 18.7 18.7 1 PMID:18927081 -3.2.1.220 1alpha(s)-n-deacetylisoipecoside carapichea ipecacuanha 86.3 86.3 1 PMID:18927081 -3.2.1.220 1beta(r)-6-o-methyl-n-deacetylipecoside carapichea ipecacuanha 31.1 31.1 1 PMID:18927081 -3.2.1.220 1beta(r)-n-deacetylipecoside carapichea ipecacuanha 28.2 28.2 1 PMID:18927081 -3.2.1.220 ipecoside carapichea ipecacuanha 51.6 51.6 1 PMID:18927081 -3.2.1.220 vincoside carapichea ipecacuanha 6.4 6.4 1 PMID:18927081 -3.2.1.221 3-o-methylmannose mycolicibacterium hassiacum 1.0 0.5105 2 PMID:36707645 -3.2.1.222 agarose wenyingzhuangia aestuarii 176.74 176.74 1 PMID:37479453 -3.2.1.222 funoran wenyingzhuangia aestuarii 3.95 3.95 1 PMID:37479453 -3.2.1.223 larch arabinogalactan protein bifidobacterium pseudocatenulatum 63.2 63.2 1 PMID:38047276 -3.2.1.224 4-nitrophenyl beta-d-arabinofuranoside microbacterium arabinogalactanolyticum 12.0 12.0 1 PMID:37726269 -3.2.1.225 4-nitrophenyl alpha-d-arabinofuranoside microbacterium arabinogalactanolyticum 44.4 44.4 1 PMID:37726269 -3.2.1.227 4-nitrophenyl-n-acetyllactosamine aquimarina sp. trl1 3.9 3.9 1 PMID:39239753 -3.2.1.227 4-nitrophenyl-n-acetyllactosamine paludibaculum fermentans 17.1 17.1 1 PMID:39239753 -3.2.1.227 4-nitrophenyl-n-acetyllactosamine parabacteroides distasonis 23.6 23.6 1 PMID:39239753 -3.2.1.227 4-nitrophenyl-n-acetyllactosamine planctomycetales bacterium 8.9 8.9 1 PMID:39239753 -3.2.1.227 4-nitrophenyl-n-acetyllactosamine treponema denticola 3.3 3.3 1 PMID:39239753 -3.2.1.228 funoran aquimarina sp. ad1 43.4 43.4 1 PMID:38763726 -3.2.1.23 2,4-dinitrophenyl 2-acetamido-2-deoxy-alpha-d-galactopyranosyl-(1-3)-[alpha-l-fucopyranosyl-(1-2)]-beta-d-galactopyranoside clostridium perfringens 1.75 1.75 1 PMID:19630404 -3.2.1.23 2-nitrophenyl beta-d-galactopyranoside caldicellulosiruptor saccharolyticus 149.0 149.0 1 PMID:19662397 -3.2.1.23 2-nitrophenyl beta-d-galactopyranoside escherichia coli 90.0 90.0 1 PMID:19472413 -3.2.1.23 2-nitrophenyl beta-d-galactopyranoside lacticaseibacillus casei 14.9 14.9 1 PMID:37599861 -3.2.1.23 2-nitrophenyl beta-d-galactopyranoside lactiplantibacillus pentosus 540.0 540.0 1 PMID:20669255 -3.2.1.23 2-nitrophenyl beta-d-galactopyranoside lactiplantibacillus plantarum 22.5 22.5 1 * -3.2.1.23 2-nitrophenyl beta-d-galactopyranoside lactiplantibacillus plantarum wcfs1 92.0 92.0 1 PMID:20385377 -3.2.1.23 2-nitrophenyl beta-d-galactopyranoside lathyrus oleraceus 293.9 293.9 1 PMID:19552429 -3.2.1.23 2-nitrophenyl beta-d-galactopyranoside streptococcus thermophilus 234.0 234.0 1 PMID:20472057 -3.2.1.23 2-nitrophenyl beta-d-galactopyranoside uncultured soil bacterium 386.0 107.85 4 PMID:20614217 -3.2.1.23 2-nitrophenyl beta-d-galactoside aspergillus oryzae 224.9 224.9 1 PMID:30827619 -3.2.1.23 2-nitrophenyl-beta-d-fucopyranoside alicyclobacillus acidocaldarius 1345.0 1345.0 1 PMID:18068682 -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside alicyclobacillus acidocaldarius 2657.0 1337.45 2 PMID:18068682 -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside arthrobacter psychrolactophilus 13.0 12.85 2 PMID:17459724;PMID:19943044 -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside arthrobacter sp. 212.4 102.45 6 PMID:19631003 -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside aspergillus carbonarius 440.0 268.0 2 PMID:18401743 -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside bos taurus 0.08 0.08 1 * -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside caldicellulosiruptor saccharolyticus 149.0 149.0 1 PMID:19943044 -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside escherichia coli 620.0 400.0 3 PMID:19936901 -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside kluyveromyces marxianus 8559.0 8559.0 3 PMID:17625262 -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside kluyveromyces sp. 0.066 0.059 3 PMID:34883192 -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside lactobacillus acidophilus 50.0 50.0 1 PMID:19943044 -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside lactobacillus delbrueckii 47.2 47.2 1 PMID:19786095 -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside limosilactobacillus reuteri 338.0 338.0 1 PMID:19943044 -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside penicillium canescens 45.4 45.4 1 * -3.2.1.23 2-nitrophenyl-beta-d-galactopyranoside saccharolobus solfataricus 5700.0 2897.5 2 PMID:19943044;PMID:2105216 -3.2.1.23 2-nitrophenyl-beta-d-galactoside kluyveromyces marxianus 8559.0 8559.0 1 PMID:17625262 -3.2.1.23 4-methylumbelliferyl beta-d-galactoside tenebrio molitor 1.7 1.7 1 PMID:12535683 -3.2.1.23 4-nitrophenyl beta-d-fucopyranoside putranjiva roxburghii 14.77 13.74 2 PMID:28500928 -3.2.1.23 4-nitrophenyl beta-d-fucopyranoside uncultured microorganism 600.0 142.0 5 PMID:27557720 -3.2.1.23 4-nitrophenyl beta-d-galactopyranoside aspergillus oryzae 525.0 525.0 1 PMID:30980597 -3.2.1.23 4-nitrophenyl beta-d-galactopyranoside caldicellulosiruptor saccharolyticus 32.0 32.0 1 PMID:19662397 -3.2.1.23 4-nitrophenyl beta-d-galactopyranoside escherichia coli 620.0 620.0 1 PMID:19472413 -3.2.1.23 4-nitrophenyl beta-d-galactopyranoside lacticaseibacillus casei 10.8 10.8 1 PMID:37599861 -3.2.1.23 4-nitrophenyl beta-d-galactopyranoside putranjiva roxburghii 7.39 6.605 2 PMID:28500928 -3.2.1.23 4-nitrophenyl beta-d-galactopyranoside saccharopolyspora rectivirgula 56.0 56.0 1 PMID:19943044 -3.2.1.23 4-nitrophenyl beta-d-galactopyranoside uncultured microorganism 197.0 129.0 5 PMID:27557720 -3.2.1.23 4-nitrophenyl beta-d-glucopyranoside putranjiva roxburghii 12.0 11.195 2 PMID:28500928 -3.2.1.23 4-nitrophenyl beta-d-glucopyranoside uncultured microorganism 286.0 108.0 5 PMID:27557720 -3.2.1.23 4-nitrophenyl-alpha-l-arabinopyranoside alicyclobacillus acidocaldarius 1740.0 1740.0 1 PMID:18068682 -3.2.1.23 4-nitrophenyl-beta-d-galactopyranoside alicyclobacillus acidocaldarius 2988.0 2988.0 1 PMID:18068682 -3.2.1.23 4-nitrophenyl-beta-d-galactopyranoside aspergillus aculeatus 932.0 932.0 1 PMID:19943044 -3.2.1.23 4-nitrophenyl-beta-d-galactopyranoside aspergillus carbonarius 74000.0 44875.0 2 PMID:18401743 -3.2.1.23 4-nitrophenyl-beta-d-galactopyranoside caldicellulosiruptor saccharolyticus 32.0 32.0 1 PMID:19943044 -3.2.1.23 4-nitrophenyl-beta-d-galactopyranoside kluyveromyces marxianus 270000.0 270000.0 2 PMID:17625262 -3.2.1.23 4-nitrophenyl-beta-d-galactopyranoside xanthomonas phaseoli pv. manihotis 2140.0 2140.0 1 PMID:16844121 -3.2.1.23 4-nitrophenyl-beta-d-galactoside kluyveromyces marxianus 2700000.0 2700000.0 1 PMID:17625262 -3.2.1.23 alpha-d-xyl-(1->6)-beta-d-glc-(1->4)-[beta-d-gal-(1->2)-alpha-d-xyl-(1->6)]-beta-d-glc-(1->4)-[beta-d-gal-(1->2)-alpha-d-xyl-(1->6)]-beta-d-glc-(1->4)-beta-d-glc aspergillus oryzae 65.0 65.0 1 PMID:30980597 -3.2.1.23 beta-d-gal-(1->2)-alpha-d-xyl-(1->6)-beta-d-glc-(1->4)-beta-d-glc aspergillus oryzae 289.0 289.0 1 PMID:30980597 -3.2.1.23 beta-d-galactosyl azide escherichia coli 26.0 26.0 1 * -3.2.1.23 beta-lactose thermomyces lanuginosus 18.0 18.0 1 PMID:7747967 -3.2.1.23 cellobiose putranjiva roxburghii 8.12 7.535 2 PMID:28500928 -3.2.1.23 galbeta1-3galnac lacticaseibacillus casei 10.2 10.2 1 PMID:37599861 -3.2.1.23 galbeta1-3glcnac lacticaseibacillus casei 10.8 10.8 1 PMID:37599861 -3.2.1.23 lactose alicyclobacillus acidocaldarius 212.0 212.0 1 PMID:18068682 -3.2.1.23 lactose arthrobacter psychrolactophilus 3.02 3.01 2 PMID:17459724;PMID:19943044 -3.2.1.23 lactose arthrobacter sp. 6.98 5.005 8 PMID:12949099;PMID:16736094;PMID:19631003 -3.2.1.23 lactose aspergillus aculeatus 254.0 254.0 1 PMID:19943044 -3.2.1.23 lactose aspergillus carbonarius 55.0 34.0 2 PMID:18401743 -3.2.1.23 lactose aspergillus oryzae 869.0 869.0 1 PMID:30980597 -3.2.1.23 lactose caldicellulosiruptor saccharolyticus 42.0 42.0 1 PMID:19662397 -3.2.1.23 lactose kluyveromyces marxianus 6300.0 6300.0 3 PMID:17625262 -3.2.1.23 lactose kluyveromyces sp. 0.1475 0.0905 6 PMID:34883192 -3.2.1.23 lactose lacticaseibacillus casei 0.695 0.695 1 PMID:37599861 -3.2.1.23 lactose lactiplantibacillus pentosus 20.0 20.0 1 PMID:20669255 -3.2.1.23 lactose lactiplantibacillus plantarum wcfs1 98.0 98.0 1 PMID:20385377 -3.2.1.23 lactose lactobacillus acidophilus 632.0 632.0 1 PMID:19943044 -3.2.1.23 lactose lactobacillus delbrueckii 45.7 45.7 1 PMID:19786095 -3.2.1.23 lactose lathyrus oleraceus 55.1 55.1 1 PMID:19552429 -3.2.1.23 lactose limosilactobacillus reuteri 58.0 35.5 2 PMID:16819907 -3.2.1.23 lactose pseudoalteromonas haloplanktis 33.0 33.0 1 PMID:11282601 -3.2.1.23 lactose saccharolobus solfataricus 122.6 114.0 3 PMID:19943044;PMID:2105216;PMID:23411285 -3.2.1.23 lactose saccharopolyspora rectivirgula 63.1 63.05 2 PMID:19943044 -3.2.1.23 lactose tenebrio molitor 1.2 1.2 1 PMID:12535683 -3.2.1.23 lactose thermus sp. 12.5 12.5 1 PMID:9757561 -3.2.1.23 lactose uncultured soil bacterium 141.0 72.5 4 PMID:20614217 -3.2.1.23 lactulose alicyclobacillus acidocaldarius 380.0 380.0 1 PMID:18068682 -3.2.1.23 lactulose thermomyces lanuginosus 33.0 33.0 1 PMID:7747967 -3.2.1.23 methyl-beta-d-galactopyranoside saccharolobus solfataricus 242.0 242.0 1 PMID:2105216 -3.2.1.23 methyl-beta-d-galactoside thermomyces lanuginosus 16.0 16.0 1 PMID:7747967 -3.2.1.23 o-nitrophenyl beta-d-galactopyranoside arthrobacter sp. 110.1 78.6 4 PMID:12949099 -3.2.1.23 o-nitrophenyl beta-d-galactopyranoside planococcus sp. (in: firmicutes) 603.0 288.0 5 PMID:10831422 -3.2.1.23 o-nitrophenyl beta-d-galactopyranoside pseudoalteromonas haloplanktis 203.0 203.0 1 PMID:11282601 -3.2.1.23 o-nitrophenyl-beta-d-galactoside kluyveromyces lactis 888.0 5.0 3 PMID:3145202 -3.2.1.23 o-nitrophenyl-beta-d-galactoside limosilactobacillus reuteri 338.0 338.0 1 PMID:16819907 -3.2.1.23 o-nitrophenyl-beta-d-galactoside saccharopolyspora rectivirgula 47.6 47.6 1 * -3.2.1.23 o-nitrophenyl-beta-d-galactoside thermoanaerobacter sp. 431.0 431.0 1 * -3.2.1.23 o-nitrophenyl-beta-d-galactoside thermoanaerobacterium thermosulfurigenes 264.0 159.25 2 PMID:8968953 -3.2.1.23 o-nitrophenyl-beta-d-galactoside thermomyces lanuginosus 941.0 941.0 1 PMID:7747967 -3.2.1.23 o-nitrophenyl-beta-d-galactoside thermus sp. 66.7 66.7 1 PMID:9757561 -3.2.1.23 p-nitrophenyl beta-d-fucoside tenebrio molitor 2.4 2.4 1 PMID:12535683 -3.2.1.23 p-nitrophenyl-alpha-l-arabinoside thermomyces lanuginosus 5000.0 5000.0 1 PMID:7747967 -3.2.1.23 p-nitrophenyl-beta-d-galactoside saccharopolyspora rectivirgula 55.8 55.8 1 * -3.2.1.23 p-nitrophenyl-beta-d-galactoside thermoanaerobacterium thermosulfurigenes 312.0 177.2 2 PMID:8968953 -3.2.1.23 p-nitrophenyl-beta-d-galactoside thermomyces lanuginosus 1040.0 1040.0 1 PMID:7747967 -3.2.1.23 phenyl-beta-d-galactopyranoside saccharolobus solfataricus 166.0 166.0 1 PMID:2105216 -3.2.1.23 phenyl-beta-d-galactoside thermomyces lanuginosus 65.0 65.0 1 PMID:7747967 -3.2.1.24 2,4-dinitrophenyl alpha-d-mannoside drosophila melanogaster 8.6 8.6 1 PMID:12960159 -3.2.1.24 2,4-dinitrophenyl-alpha-d-mannopyranoside trichoderma reesei 1.7 1.7 1 PMID:12202255 -3.2.1.24 3-o-alpha-d-mannopyranosyl-alpha-d-mannopyranose streptococcus pyogenes m1 gas 6.4 6.4 1 PMID:20140249 -3.2.1.24 4-methylumbelliferyl alpha-d-mannopyranoside streptococcus pyogenes m1 gas 0.03 0.03 1 PMID:20140249 -3.2.1.24 4-nitrophenyl alpha-d-mannopyranoside canavalia ensiformis 44.0 44.0 1 PMID:19154123 -3.2.1.24 4-nitrophenyl alpha-d-mannoside saccharolobus solfataricus 158.0 12.5 11 PMID:20696204;PMID:22989181;PMID:25751413 -3.2.1.24 5-fluoro-beta-l-gulosyl fluoride drosophila melanogaster 0.0051 0.0051 1 PMID:12960159 -3.2.1.24 alpha-d-man-(1->2)-d-man saccharolobus solfataricus 5.5 4.3 2 PMID:22989181 -3.2.1.24 alpha-d-man-(1->3)-d-man saccharolobus solfataricus 4.9 4.9 1 PMID:22989181 -3.2.1.24 alpha-d-man-(1->4)-d-man saccharolobus solfataricus 10.4 6.15 2 PMID:22989181 -3.2.1.24 alpha-d-man-(1->6)-d-man saccharolobus solfataricus 2.0 2.0 1 PMID:22989181 -3.2.1.24 p-nitrophenyl-alpha-d-mannopyranoside canavalia ensiformis 130.0 130.0 1 PMID:3370126 -3.2.1.25 2,4-dinitrophenyl-beta-d-mannopyranoside bacteroides thetaiotaomicron 214.4 214.4 1 PMID:17287210 -3.2.1.25 4-nitrophenyl beta-d-fucopyranoside thermococcus kodakarensis 322.25 322.25 1 PMID:26138395 -3.2.1.25 4-nitrophenyl beta-d-galactopyranoside pyrococcus horikoshii 13.5 13.5 1 PMID:11900558 -3.2.1.25 4-nitrophenyl beta-d-glucopyranoside pyrococcus horikoshii 34.4 34.4 1 PMID:11900558 -3.2.1.25 4-nitrophenyl beta-d-glucopyranoside thermococcus kodakarensis 227.64 227.64 1 PMID:26138395 -3.2.1.25 4-nitrophenyl beta-d-mannopyranoside pyrococcus horikoshii 4.2 4.2 1 PMID:11900558 -3.2.1.25 4-nitrophenyl beta-d-mannopyranoside thermococcus kodakarensis 50.99 50.99 1 PMID:26138395 -3.2.1.25 4-nitrophenyl-beta-d-glucopyranose hordeum vulgare 0.5 0.5 1 PMID:20825165 -3.2.1.25 4-nitrophenyl-beta-d-mannopyranose cellvibrio mixtus 0.033 0.033 1 PMID:15014076 -3.2.1.25 4-nitrophenyl-beta-d-mannopyranose hordeum vulgare 3.1 3.1 1 PMID:20825165 -3.2.1.25 4-o-beta-d-mannopyranosyl-d-mannopyranose cellvibrio mixtus 2.17 2.17 1 PMID:15014076 -3.2.1.25 beta-d-mannosyl-1,4-beta-d-glucoside cellvibrio mixtus 0.053 0.053 1 PMID:15014076 -3.2.1.25 mannotriose cellvibrio mixtus 166.7 166.7 1 PMID:15014076 -3.2.1.25 p-nitrophenyl beta-d-mannopyranoside thermotoga neapolitana 67.8 67.8 1 PMID:11210502 -3.2.1.25 p-nitrophenyl-beta-d-mannopyranoside bacteroides thetaiotaomicron 157.0 142.55 2 PMID:17287210 -3.2.1.26 1-kestose bifidobacterium adolescentis 107.0 107.0 1 PMID:20380746 -3.2.1.26 1-kestose lacticaseibacillus paracasei 64.0 64.0 1 PMID:20153640 -3.2.1.26 1-kestose phaffia rhodozyma 1.5 1.5 1 PMID:19088319 -3.2.1.26 1-kestose schwanniomyces occidentalis 26.3 26.3 1 PMID:17904238 -3.2.1.26 fructosylnystose bifidobacterium adolescentis 75.4 75.4 1 PMID:20380746 -3.2.1.26 inulin bifidobacterium adolescentis 77.4 77.4 1 PMID:20380746 -3.2.1.26 inulin lacticaseibacillus paracasei 106.0 106.0 1 PMID:20153640 -3.2.1.26 inulin leishmania major 4.2 4.2 1 PMID:26279524 -3.2.1.26 inulin schwanniomyces occidentalis 25.0 25.0 1 PMID:20181943 -3.2.1.26 inulin thermotoga maritima 590.0 590.0 1 PMID:9720201 -3.2.1.26 levan lacticaseibacillus paracasei 89.0 89.0 1 PMID:20153640 -3.2.1.26 neokestose bifidobacterium adolescentis 142.7 142.7 1 PMID:20380746 -3.2.1.26 nystose bifidobacterium adolescentis 152.8 152.8 1 PMID:20380746 -3.2.1.26 nystose lacticaseibacillus paracasei 95.0 95.0 1 PMID:20153640 -3.2.1.26 nystose schwanniomyces occidentalis 6.9 6.9 1 PMID:17904238 -3.2.1.26 raffinose lacticaseibacillus paracasei 16.0 16.0 1 PMID:20153640 -3.2.1.26 raffinose leishmania major 118.0 118.0 1 PMID:26279524 -3.2.1.26 raffinose schwanniomyces occidentalis 10.9 10.9 1 PMID:17904238 -3.2.1.26 raffinose thermotoga maritima 140.0 140.0 1 PMID:9720201 -3.2.1.26 stachyose leishmania major 409.0 409.0 1 PMID:26279524 -3.2.1.26 sucrose arthrobacter globiformis 127.0 127.0 1 PMID:15127791 -3.2.1.26 sucrose aspergillus tamarii 0.525 0.321 2 PMID:31269326 -3.2.1.26 sucrose azotobacter chroococcum 100.0 100.0 1 * -3.2.1.26 sucrose bambusa oldhamii 501.7 501.7 1 PMID:19010503 -3.2.1.26 sucrose bifidobacterium adolescentis 79.4 79.4 1 PMID:20380746 -3.2.1.26 sucrose bombyx mori 2.43 2.43 1 PMID:29055702 -3.2.1.26 sucrose cyberlindnera jadinii 2428.0 1078.0 11 PMID:19020964 -3.2.1.26 sucrose elsholtzia haichowensis 450.9 429.24 3 PMID:26123289 -3.2.1.26 sucrose lacticaseibacillus paracasei 84.0 84.0 1 PMID:20153640 -3.2.1.26 sucrose leishmania major 114.0 114.0 1 PMID:26279524 -3.2.1.26 sucrose nostoc sp. pcc 7120 = fachb-418 163.8 118.75 2 PMID:29578606 -3.2.1.26 sucrose phaffia rhodozyma 5.7 5.6899999999999995 2 PMID:19088319 -3.2.1.26 sucrose saccharomyces cerevisiae 3430.0 3430.0 1 PMID:21764973 -3.2.1.26 sucrose saccharum officinarum 21.0 21.0 1 PMID:19091583 -3.2.1.26 sucrose schwanniomyces occidentalis 106.0 84.0 3 PMID:17904238;PMID:20181943 -3.2.1.26 sucrose solanum lycopersicum 1384.0 1384.0 1 PMID:24374160 -3.2.1.26 sucrose thermotoga maritima 2600.0 2600.0 1 PMID:9720201 -3.2.1.26 sucrose thermotoga neapolitana 7300000.0 7300000.0 1 PMID:19125220 -3.2.1.26 sucrose uncultured bacterium 1448.0 1448.0 1 PMID:23638032 -3.2.1.26 sucrose zymomonas mobilis 50000.0 10396.0 9 PMID:18303841;PMID:26777250 -3.2.1.28 alpha,alpha-trehalose enterobacter cloacae 104.25 104.25 1 PMID:30657252 -3.2.1.28 alpha,alpha-trehalose metarhizium anisopliae 1.02 0.98 2 PMID:15170238 -3.2.1.28 alpha,alpha-trehalose metarhizium flavoviride 0.67 0.67 1 PMID:15170238 -3.2.1.28 alpha,alpha-trehalose spodoptera frugiperda 730.0 730.0 1 PMID:20691783 -3.2.1.28 alpha,alpha-trehalose thermoplasma volcanium 15.7 15.7 1 PMID:33791835 -3.2.1.28 alpha,alpha-trehalose zunongwangia sp. 263.25 263.25 1 PMID:26822136 -3.2.1.28 trehalose apis mellifera 662.0 662.0 1 PMID:17827701 -3.2.1.28 trehalose escherichia coli 199.0 199.0 1 PMID:17455176 -3.2.1.28 trehalose trichoderma reesei 167.0 167.0 1 PMID:31976 -3.2.1.3 4-nitrophenyl alpha-d-glucoside aspergillus awamori 0.25 0.25 1 PMID:9521694 -3.2.1.3 alpha-d-glucopyranosyl fluoride aspergillus awamori 300.0 300.0 1 PMID:9521694 -3.2.1.3 amylopectin paecilomyces variotii 34.1 34.1 1 PMID:17938981 -3.2.1.3 amylopectin saccharomyces cerevisiae 683.0 683.0 1 PMID:3124820 -3.2.1.3 amylose paecilomyces variotii 37.7 36.5 3 PMID:17938981 -3.2.1.3 cassava starch rhizopus sp. 7.1 7.1 1 PMID:17420602 -3.2.1.3 dextrin saccharomyces cerevisiae 413.0 413.0 1 PMID:3124820 -3.2.1.3 glycogen paecilomyces variotii 22.1 22.1 1 PMID:17938981 -3.2.1.3 glycogen saccharomyces cerevisiae 328.0 328.0 1 PMID:3124820 -3.2.1.3 isomaltoheptaose aspergillus awamori 1.3 1.3 1 PMID:11150611 -3.2.1.3 isomaltohexaose aspergillus awamori 1.5 1.5 1 PMID:11150611 -3.2.1.3 isomaltopentaose aspergillus awamori 1.2 1.2 1 PMID:11150611 -3.2.1.3 isomaltose aspergillus awamori 0.72 0.33999999999999997 4 PMID:11150611;PMID:7716159;PMID:9521694;PMID:9681871 -3.2.1.3 isomaltose caldanaerobacter subterraneus subsp. tengcongensis mb4 10.7 10.7 1 PMID:20155355 -3.2.1.3 isomaltose paecilomyces variotii 0.4 0.4 1 * -3.2.1.3 isomaltose rasamsonia emersonii 2.7 2.7 1 PMID:12356463 -3.2.1.3 isomaltose saccharomyces cerevisiae 6.0 6.0 1 PMID:3124820 -3.2.1.3 isomaltotetraose aspergillus awamori 0.99 0.99 1 PMID:11150611 -3.2.1.3 isomaltotriose aspergillus awamori 0.64 0.64 1 PMID:11150611 -3.2.1.3 kojibiose aspergillus awamori 0.13 0.13 1 PMID:9521694 -3.2.1.3 maize starch rhizopus sp. 6.2 6.2 1 PMID:17420602 -3.2.1.3 maltoheptaose aspergillus awamori 72.3 60.0 4 PMID:11150611;PMID:7716159;PMID:9521694;PMID:9681871 -3.2.1.3 maltoheptaose caldanaerobacter subterraneus subsp. tengcongensis mb4 343.0 343.0 1 PMID:20155355 -3.2.1.3 maltoheptaose caulobacter vibrioides 114.0 114.0 1 PMID:24468405 -3.2.1.3 maltoheptaose paecilomyces variotii 46.6 46.6 1 * -3.2.1.3 maltoheptaose rasamsonia emersonii 221.3 221.3 1 PMID:12356463 -3.2.1.3 maltoheptaose saccharomyces cerevisiae 823.0 823.0 1 PMID:3124820 -3.2.1.3 maltoheptaose thermoactinomyces vulgaris 61.6 61.6 1 PMID:14981306 -3.2.1.3 maltohexaose aspergillus awamori 49.0 49.0 2 PMID:11150611;PMID:9521694 -3.2.1.3 maltohexaose caldanaerobacter subterraneus subsp. tengcongensis mb4 459.0 459.0 1 PMID:20155355 -3.2.1.3 maltohexaose caulobacter vibrioides 125.0 125.0 1 PMID:24468405 -3.2.1.3 maltohexaose paecilomyces variotii 41.6 41.6 1 * -3.2.1.3 maltohexaose rhizopus arrhizus 71.3 54.849999999999994 2 PMID:20549574 -3.2.1.3 maltohexaose saccharomyces cerevisiae 717.0 717.0 1 PMID:3124820 -3.2.1.3 maltohexaose thermoactinomyces vulgaris 55.0 55.0 1 PMID:14981306 -3.2.1.3 maltopentaose aspergillus awamori 44.0 35.65 2 PMID:11150611;PMID:9521694 -3.2.1.3 maltopentaose caldanaerobacter subterraneus subsp. tengcongensis mb4 518.0 518.0 1 PMID:20155355 -3.2.1.3 maltopentaose caulobacter vibrioides 122.0 122.0 1 PMID:24468405 -3.2.1.3 maltopentaose paecilomyces variotii 41.1 41.1 1 * -3.2.1.3 maltopentaose rhizopus arrhizus 73.7 58.75 2 PMID:20549574 -3.2.1.3 maltopentaose saccharomyces cerevisiae 800.0 800.0 1 PMID:3124820 -3.2.1.3 maltopentaose thermoactinomyces vulgaris 56.3 56.3 1 PMID:14981306 -3.2.1.3 maltose aspergillus awamori 20.4 8.9 9 PMID:11054460;PMID:11150611;PMID:12646689;PMID:7716159;PMID:9056481;PMID:9521694;PMID:9681871 -3.2.1.3 maltose aspergillus niger 7.55 0.485 4 PMID:11150611 -3.2.1.3 maltose caldanaerobacter subterraneus subsp. tengcongensis mb4 149.0 149.0 1 PMID:20155355 -3.2.1.3 maltose caulobacter vibrioides 38.2 38.2 1 PMID:24468405 -3.2.1.3 maltose clostridium thermoamylolyticum 7.1 7.1 1 * -3.2.1.3 maltose paecilomyces variotii 7.2 7.2 1 * -3.2.1.3 maltose rasamsonia emersonii 31.3 31.3 1 PMID:12356463 -3.2.1.3 maltose rhizopus arrhizus 9.3 7.69 2 PMID:20549574 -3.2.1.3 maltose saccharomyces cerevisiae 52.0 52.0 1 PMID:3124820 -3.2.1.3 maltose saccharophagus degradans 8.9 8.9 1 PMID:34041001 -3.2.1.3 maltose thermoactinomyces vulgaris 16.9 16.9 1 PMID:14981306 -3.2.1.3 maltose thermoanaerobacter ethanolicus 99.0 99.0 1 PMID:35997915 -3.2.1.3 maltose thermomyces lanuginosus 25.3 25.3 1 PMID:16488199 -3.2.1.3 maltotetraose aspergillus awamori 45.0 45.0 3 PMID:11150611;PMID:9056481;PMID:9521694 -3.2.1.3 maltotetraose aspergillus niger 3.2 3.2 1 PMID:11150611 -3.2.1.3 maltotetraose caldanaerobacter subterraneus subsp. tengcongensis mb4 460.0 460.0 1 PMID:20155355 -3.2.1.3 maltotetraose caulobacter vibrioides 155.0 155.0 1 PMID:24468405 -3.2.1.3 maltotetraose paecilomyces variotii 43.4 43.4 1 * -3.2.1.3 maltotetraose rhizopus arrhizus 71.1 55.55 2 PMID:20549574 -3.2.1.3 maltotetraose saccharomyces cerevisiae 720.0 720.0 1 PMID:3124820 -3.2.1.3 maltotetraose thermoactinomyces vulgaris 70.7 36.15 2 PMID:14981306 -3.2.1.3 maltotriose aspergillus awamori 33.5 28.0 5 PMID:11150611;PMID:9056481;PMID:9521694 -3.2.1.3 maltotriose caldanaerobacter subterraneus subsp. tengcongensis mb4 368.0 368.0 1 PMID:20155355 -3.2.1.3 maltotriose caulobacter vibrioides 150.0 150.0 1 PMID:24468405 -3.2.1.3 maltotriose paecilomyces variotii 27.2 27.2 1 * -3.2.1.3 maltotriose rhizopus arrhizus 54.7 37.1 2 PMID:20549574 -3.2.1.3 maltotriose saccharomyces cerevisiae 330.0 330.0 1 PMID:3124820 -3.2.1.3 maltotriose thermoactinomyces vulgaris 76.4 76.4 1 PMID:14981306 -3.2.1.3 maltotriose thermothielavioides terrestris 91.7 91.7 1 PMID:14665735 -3.2.1.3 nigerose aspergillus awamori 0.14 0.14 1 PMID:9521694 -3.2.1.3 nigerose paecilomyces variotii 2.2 2.2 1 * -3.2.1.3 panose aspergillus awamori 6.9 6.9 1 PMID:9521694 -3.2.1.3 panose paecilomyces variotii 9.1 9.1 1 * -3.2.1.3 phenyl alpha-maltoside paecilomyces variotii 11.0 11.0 1 * -3.2.1.3 potato starch rhizopus sp. 1.6 1.6 1 PMID:17420602 -3.2.1.3 potato starch thermoanaerobacter ethanolicus 20.2 20.2 1 PMID:35997915 -3.2.1.3 rice starch rhizopus sp. 23.3 23.3 1 PMID:17420602 -3.2.1.3 soluble starch fusarium solani 7.35 7.35 1 * -3.2.1.3 soluble starch humicola sp. 69.0 69.0 1 * -3.2.1.3 soluble starch lentinula edodes 4833.0 4833.0 1 PMID:16328738 -3.2.1.3 soluble starch paecilomyces variotii 49.1 49.1 1 * -3.2.1.3 soluble starch rhizopus arrhizus 58.2 46.650000000000006 2 PMID:20549574 -3.2.1.3 starch aspergillus neotritici 67.15 67.15 1 PMID:28951303 -3.2.1.3 starch aspergillus niger 343.0 250.65 2 PMID:24293795;PMID:24837950 -3.2.1.3 starch aspergillus niveus 14.2 14.2 1 PMID:19697071 -3.2.1.3 starch fusarium solani 518.0 360.5 6 PMID:17031637;PMID:17496965 -3.2.1.3 starch gymnascella citrina 8.3 4.12 3 PMID:17018008 -3.2.1.3 starch paecilomyces variotii 41.7 22.55 2 PMID:17938981 -3.2.1.3 starch saccharomyces cerevisiae 428.0 428.0 1 PMID:3124820 -3.2.1.3 starch tetracladium sp. 0.75 0.75 1 PMID:28464820 -3.2.1.3 sweet potato starch rhizopus sp. 4.6 4.6 1 PMID:17420602 -3.2.1.3 wheat starch rhizopus sp. 14.8 14.8 1 PMID:17420602 -3.2.1.31 4-methylumbelliferyl-beta-d-glucuronide homo sapiens 276.0 276.0 1 PMID:10438523 -3.2.1.31 4-nitrophenyl beta-d-galactosiduronide thermotoga maritima 443.0 443.0 1 PMID:16303119 -3.2.1.31 4-nitrophenyl beta-d-glucoside thermotoga maritima 9.0 9.0 1 PMID:16303119 -3.2.1.31 4-nitrophenyl beta-d-glucuronide escherichia coli 0.001 0.001 1 PMID:15069062 -3.2.1.31 4-nitrophenyl beta-d-glucuronide mus musculus 200.0 200.0 1 PMID:1194264 -3.2.1.31 4-nitrophenyl beta-d-glucuronide thermotoga maritima 68.0 48.5 2 PMID:16303119 -3.2.1.31 4-nitrophenyl beta-d-xylopyranoside escherichia coli 68.0 68.0 1 PMID:15069062 -3.2.1.31 4-nitrophenyl-beta-d-glucuronide escherichia coli 1500.0 1500.0 1 PMID:17557766 -3.2.1.31 4-nitrophenyl-beta-d-glucuronide homo sapiens 0.67 0.67 1 PMID:11513863 -3.2.1.31 daidzein 7-o-beta-d-glucuronide homo sapiens 1.07 1.07 1 PMID:11513863 -3.2.1.31 equol 7-o-beta-d-glucuronide homo sapiens 0.35 0.35 1 PMID:11513863 -3.2.1.31 glycyrrhetinic acid 3-o-mono-beta-d-glucuronide aspergillus oryzae 7.81 7.81 1 PMID:29146597 -3.2.1.31 glycyrrhizin aspergillus oryzae 3.23 3.23 1 PMID:29146597 -3.2.1.31 glycyrrhizin talaromyces purpureogenus 27.84 25.57 2 PMID:20607443 -3.2.1.31 kaempferol 3-o-beta-d-glucuronide homo sapiens 0.65 0.65 1 PMID:11513863 -3.2.1.31 quercetin 4'-o-beta-d-glucuronide homo sapiens 0.26 0.26 1 PMID:11513863 -3.2.1.31 quercetin 7-o-beta-d-glucuronide homo sapiens 1.65 1.65 1 PMID:11513863 -3.2.1.31 quercetin-3-o-beta-d-glucuronide homo sapiens 1.9 1.9 1 PMID:11513863 -3.2.1.32 2-oxo-4-(trifluoromethyl)-2h-chromen-7-yl 3-o-(3-o-methyl-etab-d-xylopyranosyl)-beta-d-xylopyranoside vibrio sp. 2.1 2.1 1 PMID:22296113 -3.2.1.32 2-oxo-4-(trifluoromethyl)-2h-chromen-7-yl 3-o-beta-d-xylopyranosyl-beta-d-xylopyranoside vibrio sp. 1.9 1.9 1 PMID:22296113 -3.2.1.32 2-oxo-4-(trifluoromethyl)-2h-chromen-7-yl beta-d-xylopyranosyl-(1->3)-beta-d-xylopyranosyl-(1->3)-beta-d-xylopyranoside vibrio sp. 0.89 0.89 1 PMID:22296113 -3.2.1.32 beta-1,3-xylan flammeovirga pacifica 895.45 515.345 10 PMID:30021136;PMID:31615663;PMID:32906756;PMID:33549102 -3.2.1.32 beta-1,3-xylan synthetic construct 180.48 180.48 1 PMID:34426240 -3.2.1.32 beta-1,3-xylan thermotoga neapolitana 588.2 588.2 1 PMID:23149756 -3.2.1.32 glycol beta-1,3-xylan flammeovirga pacifica 1501.61 1139.53 8 PMID:30021136;PMID:31615663;PMID:32906756 -3.2.1.32 glycol beta-1,3-xylan synthetic construct 171.23 171.23 1 PMID:34426240 -3.2.1.32 glycol beta-1,3-xylan thermotoga neapolitana 322.6 322.6 1 PMID:23149756 -3.2.1.32 lichenin synthetic construct 3560.58 3560.58 1 PMID:34426240 -3.2.1.32 xylopentaose vibrio sp. 14000.0 14000.0 1 PMID:15743273 -3.2.1.32 xylotetraose vibrio sp. 350.0 350.0 1 PMID:15743273 -3.2.1.33 6-o-alpha-maltotetraosyl-beta-cyclodextrin saccharolobus solfataricus 2570.0 2570.0 1 PMID:24610710 -3.2.1.33 amylopectin saccharolobus solfataricus 17.35 4.2465 4 * -3.2.1.33 de16 maltodextrin saccharolobus solfataricus 1.75 1.75 1 PMID:37463425 -3.2.1.33 de19 maltodextrin saccharolobus solfataricus 1.62 1.62 1 PMID:37463425 -3.2.1.33 de2 maltodextrin saccharolobus solfataricus 2.66 2.66 1 PMID:37463425 -3.2.1.33 de4 maltodextrin saccharolobus solfataricus 3.56 3.56 1 PMID:37463425 -3.2.1.33 de9 maltodextrin saccharolobus solfataricus 2.24 2.24 1 PMID:37463425 -3.2.1.33 maize amylopectin saccharolobus solfataricus 0.06 0.06 1 PMID:37463425 -3.2.1.33 maltodecaose nostoc punctiforme 0.045 0.045 1 PMID:19010304 -3.2.1.33 maltododecaose nostoc punctiforme 0.0478 0.0478 1 PMID:19010304 -3.2.1.33 maltononaose nostoc punctiforme 0.0205 0.0205 1 PMID:19010304 -3.2.1.33 maltoundecaose nostoc punctiforme 0.0452 0.0452 1 PMID:19010304 -3.2.1.33 potato amylopectin saccharolobus solfataricus 0.07 0.07 1 PMID:37463425 -3.2.1.37 10-deacetyl-7-xylosyltaxol dictyoglomus turgidum 3.437 3.437 1 PMID:31668798 -3.2.1.37 2,4-dinitrophenyl-beta-d-xylopyranoside trichoderma koningii 3.89 3.89 1 PMID:10731699 -3.2.1.37 2,5-dinitrophenyl-beta-d-xylopyranoside geobacillus stearothermophilus 25.0 25.0 1 PMID:15628881 -3.2.1.37 2,5-dinitrophenyl-beta-d-xylopyranoside trichoderma koningii 4.72 4.72 1 PMID:10731699 -3.2.1.37 2-nitrophenyl xylopyranoside rasamsonia emersonii 96.0 96.0 1 * -3.2.1.37 2-nitrophenyl-beta-d-xylopyranoside trichoderma koningii 3.48 3.48 1 PMID:10731699 -3.2.1.37 3,4-dinitrophenyl beta-d-xylopyranoside aspergillus niger 93.8 93.8 1 PMID:36877249 -3.2.1.37 3,4-dinitrophenyl beta-d-xyloside aspergillus niger 93.8 93.8 1 PMID:26166179 -3.2.1.37 3,4-dinitrophenyl-beta-d-xylopyranoside geobacillus stearothermophilus 77.0 77.0 1 PMID:15628881 -3.2.1.37 3,4-dinitrophenyl-beta-d-xylopyranoside trichoderma koningii 4.8 4.8 1 PMID:10731699 -3.2.1.37 3-nitrophenyl-beta-d-xylopyranoside trichoderma koningii 5.22 5.22 1 PMID:10731699 -3.2.1.37 4-chloro-2-nitrophenyl-beta-d-xylopyranoside trichoderma koningii 3.9 3.9 1 PMID:10731699 -3.2.1.37 4-cyanophenyl-beta-d-xylopyranoside trichoderma koningii 3.28 3.28 1 PMID:10731699 -3.2.1.37 4-methylumbelliferyl-alpha-l-arabinofuranoside geobacillus thermoleovorans 0.233 0.233 1 PMID:18815904 -3.2.1.37 4-methylumbelliferyl-beta-d-xylopyranoside geobacillus stearothermophilus 20.0 20.0 1 PMID:15628881 -3.2.1.37 4-methylumbelliferyl-beta-d-xylopyranoside geobacillus thermoleovorans 0.208 0.208 1 PMID:18815904 -3.2.1.37 4-nitrophenyl alpha-d-xylopyranoside talaromyces purpureogenus 253.3 253.3 1 PMID:20562284 -3.2.1.37 4-nitrophenyl alpha-l-arabinofuranoside irpex lacteus 2.81 2.81 1 PMID:30138852 -3.2.1.37 4-nitrophenyl alpha-l-arabinofuranoside massilia sp. rbm26 2.04 2.04 1 PMID:31109875 -3.2.1.37 4-nitrophenyl alpha-l-arabinofuranoside talaromyces amestolkiae 143.0 143.0 1 PMID:26150469 -3.2.1.37 4-nitrophenyl alpha-l-arabinofuranoside thermotoga petrophila 2201.64 2201.64 1 PMID:30616097 -3.2.1.37 4-nitrophenyl alpha-l-arabinopyranoside aspergillus niger 113.0 113.0 1 PMID:26166179 -3.2.1.37 4-nitrophenyl alpha-l-arabinopyranoside talaromyces amestolkiae 220.0 220.0 1 PMID:26150469 -3.2.1.37 4-nitrophenyl alpha-l-arabinopyranoside talaromyces purpureogenus 2.73 2.73 1 PMID:20562284 -3.2.1.37 4-nitrophenyl alpha-l-arabinopyranoside thermotoga petrophila 1000.73 1000.73 1 PMID:30616097 -3.2.1.37 4-nitrophenyl beta-d-glucoside aspergillus niger 17.3 15.4 2 PMID:26166179;PMID:36877249 -3.2.1.37 4-nitrophenyl beta-d-xylopyranoside anoxybacillus sp. 3m 453.29 453.29 1 PMID:30219517 -3.2.1.37 4-nitrophenyl beta-d-xylopyranoside aspergillus niger 36.08 36.08 1 PMID:29174354 -3.2.1.37 4-nitrophenyl beta-d-xylopyranoside irpex lacteus 9.4 9.4 1 PMID:30138852 -3.2.1.37 4-nitrophenyl beta-d-xylopyranoside massilia sp. rbm26 2.34 2.34 1 PMID:31109875 -3.2.1.37 4-nitrophenyl beta-d-xylopyranoside paenibacillus xylaniclasticus 2.8 2.8 1 PMID:36312872 -3.2.1.37 4-nitrophenyl beta-d-xylopyranoside rhizophlyctis rosea 21.2 21.2 1 PMID:30397764 -3.2.1.37 4-nitrophenyl beta-d-xylopyranoside selenomonas ruminantium 0.82 0.82 1 * -3.2.1.37 4-nitrophenyl beta-d-xylopyranoside talaromyces amestolkiae 173.0 173.0 1 PMID:26150469 -3.2.1.37 4-nitrophenyl beta-d-xylopyranoside thermogemmatispora tikiterensis 39.2 39.2 1 PMID:31299302 -3.2.1.37 4-nitrophenyl beta-d-xylopyranoside thermotoga petrophila 982.321 982.321 1 PMID:30616097 -3.2.1.37 4-nitrophenyl beta-d-xylopyranoside uncultured bacterium 76.0 76.0 1 PMID:21720773 -3.2.1.37 4-nitrophenyl beta-d-xylopyranoside uncultured rumen bacterium 135.0 76.0 2 PMID:22020745 -3.2.1.37 4-nitrophenyl beta-d-xyloside aspergillus niger 334.0 233.5 2 PMID:26166179;PMID:36877249 -3.2.1.37 4-nitrophenyl beta-d-xyloside cellulosimicrobium cellulans 15.4 15.4 1 * -3.2.1.37 4-nitrophenyl beta-d-xyloside dictyoglomus thermophilum 12.63 6.550000000000001 2 PMID:33242495;PMID:34649692 -3.2.1.37 4-nitrophenyl beta-d-xyloside enterobacter ludwigii 8.51 7.725 2 * -3.2.1.37 4-nitrophenyl beta-d-xyloside geobacillus thermodenitrificans 193.22 193.22 1 PMID:37487384 -3.2.1.37 4-nitrophenyl beta-d-xyloside neocallimastix californiae 29.28 29.28 1 PMID:37744100 -3.2.1.37 4-nitrophenyl beta-d-xyloside talaromyces purpureogenus 253.3 253.3 1 PMID:20562284 -3.2.1.37 4-nitrophenyl beta-d-xyloside thermobifida halotolerans 50.0 50.0 1 PMID:30225545 -3.2.1.37 4-nitrophenyl xylopyranoside rasamsonia emersonii 426.0 426.0 1 * -3.2.1.37 4-nitrophenyl-alpha-l-arabinofuranoside aspergillus awamori 31.5 31.5 1 PMID:17145041 -3.2.1.37 4-nitrophenyl-alpha-l-arabinofuranoside geobacillus thermoleovorans 1.18 1.18 1 PMID:18815904 -3.2.1.37 4-nitrophenyl-alpha-l-arabinofuranoside medicago sativa 4.7 4.7 1 PMID:17615411 -3.2.1.37 4-nitrophenyl-alpha-l-arabinofuranoside selenomonas ruminantium 3.34 3.14 5 PMID:18973836;PMID:20127424 -3.2.1.37 4-nitrophenyl-alpha-l-arabinopyranoside medicago sativa 1.75 1.75 1 PMID:17615411 -3.2.1.37 4-nitrophenyl-beta-d-fucopyranoside aspergillus awamori 0.001 0.001 1 PMID:17145041 -3.2.1.37 4-nitrophenyl-beta-d-glucopyranoside aspergillus awamori 0.24 0.24 1 PMID:17145041 -3.2.1.37 4-nitrophenyl-beta-d-xylopyranoside arabidopsis thaliana 1.65 1.5 2 PMID:15181203 -3.2.1.37 4-nitrophenyl-beta-d-xylopyranoside aspergillus awamori 17.5 17.5 1 PMID:17145041 -3.2.1.37 4-nitrophenyl-beta-d-xylopyranoside geobacillus stearothermophilus 57.0 57.0 1 PMID:15628881 -3.2.1.37 4-nitrophenyl-beta-d-xylopyranoside geobacillus thermoleovorans 0.18 0.18 1 PMID:18815904 -3.2.1.37 4-nitrophenyl-beta-d-xylopyranoside halalkalibacterium halodurans 5.26 5.26 1 * -3.2.1.37 4-nitrophenyl-beta-d-xylopyranoside medicago sativa 0.96 0.96 1 PMID:17615411 -3.2.1.37 4-nitrophenyl-beta-d-xylopyranoside rasamsonia emersonii 0.017 0.017 1 PMID:16752410 -3.2.1.37 4-nitrophenyl-beta-d-xylopyranoside selenomonas ruminantium 32.5 29.3 5 PMID:18973836;PMID:20127424 -3.2.1.37 4-nitrophenyl-beta-d-xylopyranoside thermoanaerobacterium saccharolyticum 189.3 189.3 1 PMID:21131522 -3.2.1.37 4-nitrophenyl-beta-d-xylopyranoside trichoderma koningii 3.04 3.04 1 PMID:10731699 -3.2.1.37 4-nitrophenyl-beta-d-xylopyranoside trichoderma reesei 0.0147 0.0147 1 PMID:16752410 -3.2.1.37 4-nitrophenyl-beta-d-xylopyranoside xylanibacter ruminicola 9.7 9.7 1 PMID:19304844 -3.2.1.37 4-nitrophenyl-beta-d-xylopyranoside zea mays 6.5 6.5 1 * -3.2.1.37 beechwood xylan talaromyces amestolkiae 229.0 229.0 1 PMID:26150469 -3.2.1.37 beechwood xylan thermogemmatispora tikiterensis 2.24 2.24 1 PMID:31299302 -3.2.1.37 cellobiose aspergillus niger 0.0034 0.0034 1 PMID:36877249 -3.2.1.37 p-nitrophenyl alpha-l-arabinoside thermobifida halotolerans 3.8 3.8 1 PMID:30225545 -3.2.1.37 p-nitrophenyl-beta-d-xylopyranoside thermoanaerobacterium saccharolyticum 4.0 4.0 1 PMID:12146939 -3.2.1.37 phenyl-beta-d-xylopyranoside trichoderma koningii 5.13 5.13 1 PMID:10731699 -3.2.1.37 xylobiose aspergillus niger 94.8 81.3 2 PMID:26166179;PMID:36877249 -3.2.1.37 xylobiose enterobacter sp. 1.9 1.9 1 PMID:29876606 -3.2.1.37 xylobiose geobacillus thermoleovorans 0.065 0.065 1 PMID:18815904 -3.2.1.37 xylobiose halalkalibacterium halodurans 0.32 0.32 1 * -3.2.1.37 xylobiose rasamsonia emersonii 0.002 0.002 1 PMID:16752410 -3.2.1.37 xylobiose talaromyces amestolkiae 183.0 183.0 1 PMID:26150469 -3.2.1.37 xylobiose trichoderma reesei 0.0044 0.0044 1 PMID:16752410 -3.2.1.37 xylohexaose enterobacter sp. 5.6 5.6 1 PMID:29876606 -3.2.1.37 xylohexaose rasamsonia emersonii 0.0029 0.0029 1 PMID:16752410 -3.2.1.37 xylohexaose talaromyces amestolkiae 32.0 32.0 1 PMID:26150469 -3.2.1.37 xylohexaose trichoderma reesei 0.002 0.002 1 PMID:16752410 -3.2.1.37 xylopentaose enterobacter sp. 5.8 5.8 1 PMID:29876606 -3.2.1.37 xylopentaose rasamsonia emersonii 0.0034 0.0034 1 PMID:16752410 -3.2.1.37 xylopentaose talaromyces amestolkiae 39.2 39.2 1 PMID:26150469 -3.2.1.37 xylopentaose trichoderma reesei 0.003 0.003 1 PMID:16752410 -3.2.1.37 xylotetraose enterobacter sp. 6.0 6.0 1 PMID:29876606 -3.2.1.37 xylotetraose rasamsonia emersonii 0.0036 0.0036 1 PMID:16752410 -3.2.1.37 xylotetraose talaromyces amestolkiae 51.2 51.2 1 PMID:26150469 -3.2.1.37 xylotetraose trichoderma reesei 0.0027 0.0027 1 PMID:16752410 -3.2.1.37 xylotriose enterobacter sp. 3.0 3.0 1 PMID:29876606 -3.2.1.37 xylotriose geobacillus thermoleovorans 0.02 0.02 1 PMID:18815904 -3.2.1.37 xylotriose halalkalibacterium halodurans 4.91 4.91 1 * -3.2.1.37 xylotriose rasamsonia emersonii 0.0037 0.0037 1 PMID:16752410 -3.2.1.37 xylotriose talaromyces amestolkiae 66.1 66.1 1 PMID:26150469 -3.2.1.37 xylotriose trichoderma reesei 0.0029 0.0029 1 PMID:16752410 -3.2.1.38 4-nitrophenyl beta-d-fucopyranoside thermococcus kodakarensis 322.25 322.25 1 PMID:26138395 -3.2.1.38 4-nitrophenyl beta-d-fucopyranoside uncultured microorganism 600.0 142.0 5 PMID:27557720 -3.2.1.38 4-nitrophenyl beta-d-galactopyranoside uncultured microorganism 197.0 129.0 5 PMID:27557720 -3.2.1.38 4-nitrophenyl beta-d-glucopyranoside thermococcus kodakarensis 227.64 227.64 1 PMID:26138395 -3.2.1.38 4-nitrophenyl beta-d-glucopyranoside uncultured microorganism 286.0 108.0 5 PMID:27557720 -3.2.1.38 4-nitrophenyl beta-d-mannopyranoside thermococcus kodakarensis 50.99 50.99 1 PMID:26138395 -3.2.1.39 barley beta-glucan bacillus tequilensis 188.9 162.95 2 PMID:27627900;PMID:28860063 -3.2.1.39 beta-glucan euglena gracilis 0.88 0.88 1 PMID:36586565 -3.2.1.39 curdlan shouchella lehensis 672.3 672.3 1 PMID:32912685 -3.2.1.39 curdlan shouchella lehensis g1 672.3 672.3 1 PMID:32912685 -3.2.1.39 laminariheptaose cellulosimicrobium cellulans 69.0 49.5 2 PMID:21979581 -3.2.1.39 laminarin aplysia kurodai 23.01 23.01 1 PMID:19883786 -3.2.1.39 laminarin azumapecten farreri 1230.6 1230.6 1 PMID:32947865 -3.2.1.39 laminarin boscia senegalensis 395.0 395.0 1 PMID:11563825 -3.2.1.39 laminarin cellulosimicrobium cellulans 35.9 25.39 2 PMID:11676595;PMID:16946451 -3.2.1.39 laminarin euglena gracilis 1.2 1.2 1 PMID:36586565 -3.2.1.39 laminarin lentinula edodes 0.84 0.84 1 PMID:21965406 -3.2.1.39 laminarin microdochium nivale 56.1 56.1 1 PMID:37774972 -3.2.1.39 laminarin shouchella lehensis 822.0 822.0 1 PMID:32912685 -3.2.1.39 laminarin shouchella lehensis g1 822.0 822.0 1 PMID:32912685 -3.2.1.39 laminarin spodoptera frugiperda 29.0 29.0 1 PMID:20816775 -3.2.1.39 laminarin tenebrio molitor 1.4 1.4 1 PMID:19840850 -3.2.1.39 laminarin thermotoga maritima 109.0 109.0 1 PMID:23081838 -3.2.1.39 laminarin thermotoga petrophila 680.3 680.3 1 PMID:21352806 -3.2.1.39 laminarin vitis vinifera 92.0 34.0 3 PMID:27216084 -3.2.1.39 laminaripentaose cellulosimicrobium cellulans 75.0 58.5 2 PMID:21979581 -3.2.1.39 laminaripentaose microdochium nivale 13.1 13.1 1 PMID:37774972 -3.2.1.39 laminaritetraose aplysia kurodai 0.19 0.19 1 PMID:19883786 -3.2.1.39 laminaritetraose microdochium nivale 17.4 17.4 1 PMID:37774972 -3.2.1.39 laminaritriose microdochium nivale 24.3 24.3 1 PMID:37774972 -3.2.1.39 lichenan thermotoga maritima 38.0 38.0 1 PMID:23081838 -3.2.1.39 paramylon euglena gracilis 0.23 0.23 1 PMID:36586565 -3.2.1.39 yeast beta-glucan euglena gracilis 0.88 0.88 1 PMID:36586565 -3.2.1.4 2',4'-dinitrophenyl-beta-d-cellobiose cellulomonas fimi 0.397 0.3775 2 PMID:8140088 -3.2.1.4 2,4-dinitrophenyl beta-d-cellobioside thermobifida fusca 0.02 0.02 1 PMID:15274620 -3.2.1.4 4-methylumbelliferyl beta-d-lactoside rasamsonia emersonii 0.55 0.535 2 PMID:19951999 -3.2.1.4 4-methylumbelliferyl cellobioside trichoderma reesei 0.01 0.01 1 PMID:25784767 -3.2.1.4 4-nitrophenyl cellobioside pyrococcus furiosus 0.79 0.79 1 PMID:9864341 -3.2.1.4 4-nitrophenyl cellobioside pyrococcus horikoshii 9.55 9.55 1 PMID:22344652 -3.2.1.4 4-nitrophenyl cellopentaoside pyrococcus furiosus 1.4 1.4 1 PMID:9864341 -3.2.1.4 4-nitrophenyl cellotetraoside pyrococcus furiosus 3.6 3.6 1 PMID:9864341 -3.2.1.4 4-nitrophenyl cellotrioside pyrococcus furiosus 8.3 8.3 1 PMID:9864341 -3.2.1.4 4-nitrophenyl d-cellobioside trichoderma reesei 0.019 0.019 1 PMID:24747898 -3.2.1.4 4-nitrophenyl d-cellobioside uncultured bacterium 466.0 466.0 1 PMID:26877766 -3.2.1.4 avicel bacterium enrichment culture 37.2 37.2 1 PMID:26052323 -3.2.1.4 avicel trichoderma atroviride 0.091 0.091 1 PMID:28155168 -3.2.1.4 barley beta-1,4-d-glucan thermochaetoides thermophila 0.0007 0.0007 1 PMID:29842954 -3.2.1.4 barley beta-glucan cellulomonas fimi 295000.0 211500.0 2 PMID:28982013 -3.2.1.4 barley beta-glucan rasamsonia emersonii 311.0 311.0 1 PMID:24668246 -3.2.1.4 barley beta-glucan talaromyces verruculosus 165.0 165.0 1 PMID:27440076 -3.2.1.4 barley beta-glucan uncultured bacterium 3276.0 3276.0 1 PMID:26877766 -3.2.1.4 beta-1,4-d-glucan thermochaetoides thermophila 0.0007 0.0007 1 PMID:29842954 -3.2.1.4 beta-1,4-d-xylan thermochaetoides thermophila 0.00158 0.00158 1 PMID:29842954 -3.2.1.4 beta-glucan acetivibrio thermocellus 0.09 0.09 1 PMID:30897487 -3.2.1.4 beta-glucan chrysosporium lucknowense 84.0 41.0 6 PMID:15193129 -3.2.1.4 beta-glucan talaromyces verruculosus 156.0 156.0 1 PMID:25869365 -3.2.1.4 beta-glucan thermotoga maritima 791.0 791.0 1 PMID:22170108 -3.2.1.4 carboxymethyl cellulose acetivibrio thermocellus 0.006 0.006 1 PMID:30897487 -3.2.1.4 carboxymethyl cellulose aspergillus niger 0.08 0.08 1 PMID:33319112 -3.2.1.4 carboxymethyl cellulose bacillus sp. (in: firmicutes) 26.0 26.0 1 PMID:22012583 -3.2.1.4 carboxymethyl cellulose bacterium enrichment culture 70.6 70.6 1 PMID:26052323 -3.2.1.4 carboxymethyl cellulose cellulomonas biazotea 217.0 217.0 1 PMID:15604759 -3.2.1.4 carboxymethyl cellulose cellulomonas fimi 5.92 5.865 2 PMID:20136145 -3.2.1.4 carboxymethyl cellulose chrysosporium lucknowense 54.0 24.5 6 PMID:15193129 -3.2.1.4 carboxymethyl cellulose gymnascella citrina 318.0 318.0 1 PMID:18228067 -3.2.1.4 carboxymethyl cellulose mahella australiensis 514.0 425.5 2 PMID:32387598 -3.2.1.4 carboxymethyl cellulose mycothermus thermophilus 677.0 576.0 2 PMID:29150773 -3.2.1.4 carboxymethyl cellulose pseudoalteromonas sp. dy3 4.2 4.2 1 PMID:29491860 -3.2.1.4 carboxymethyl cellulose rasamsonia emersonii 51.6 51.6 1 PMID:24668246 -3.2.1.4 carboxymethyl cellulose salipaludibacillus agaradhaerens 190.1 84.4 3 PMID:16710633 -3.2.1.4 carboxymethyl cellulose thermochaetoides thermophila 0.00211 0.00211 2 PMID:29842954 -3.2.1.4 carboxymethyl cellulose thermotoga petrophila 471.0 327.0 4 PMID:26122986 -3.2.1.4 carboxymethyl cellulose uncultured bacterium 49.2 49.2 1 PMID:26877766 -3.2.1.4 carboxymethyl cellulose uncultured rumen bacterium 163.0 163.0 1 * -3.2.1.4 carboxymethyl cellulose volvariella volvacea 74.51 74.51 1 PMID:29551715 -3.2.1.4 carboxymethylcellulose alicyclobacillus acidocaldarius 0.75 0.75 1 PMID:26537871 -3.2.1.4 carboxymethylcellulose bacillus subtilis 437.0 341.5 2 PMID:18632263 -3.2.1.4 carboxymethylcellulose cohnella sp. a01 0.1043 0.1043 1 PMID:35717508 -3.2.1.4 carboxymethylcellulose escherichia coli 0.16 0.16 1 PMID:26992793 -3.2.1.4 carboxymethylcellulose niallia circulans 26.4 26.4 1 PMID:12020807 -3.2.1.4 carboxymethylcellulose thermothelomyces thermophilus 1020.0 1020.0 1 PMID:28591592 -3.2.1.4 carboxymethylcellulose trichoderma atroviride 0.094 0.094 1 PMID:28155168 -3.2.1.4 carboxymethylcellulose xanthomonas campestris pv. campestris 4.6 4.6 1 PMID:27444323 -3.2.1.4 cellobiose trichoderma atroviride 0.095 0.095 1 PMID:28155168 -3.2.1.4 cellohexaose uncultured bacterium 41.7 41.7 1 PMID:26877766 -3.2.1.4 cellopentaose uncultured bacterium 42.3 42.3 1 PMID:26877766 -3.2.1.4 cellotetraose uncultured bacterium 159.0 159.0 1 PMID:26877766 -3.2.1.4 cellotriose uncultured bacterium 897.0 897.0 1 PMID:26877766 -3.2.1.4 hydroxyethylcellulose uncultured bacterium 185.6 185.6 1 PMID:26877766 -3.2.1.4 laminarin uncultured bacterium 127.5 127.5 1 PMID:26877766 -3.2.1.4 lichenan acetivibrio thermocellus 0.1 0.1 1 PMID:30897487 -3.2.1.4 n-[2-n-[(s-(4-deoxy-4-dimethylamino-phenylazophenylthioureido-beta-d-glucopyranosyl)-(1->4)-beta-d-glucopyranosyl-(1->4)-beta-d-glucopyranosyl-(1->4)-beta-d-glucopyranosyl-(1->4)-beta-d-glucopyranosyl-(1->4)-beta-d-glucopyranosyl)-2-thioacetyl]aminoethyl]-1-naphthylamine-5-sulfonate saccharolobus solfataricus 0.39 0.39 2 PMID:23627611 -3.2.1.4 n-[2-n-[(s-(4-deoxy-4-dimethylamino-phenylazophenylthioureido-beta-d-glucopyranosyl)-(1->4)-beta-d-glucopyranosyl-(1->4)-beta-d-glucopyranosyl-(1->4)-beta-d-glucopyranosyl-(1->4)-beta-d-glucopyranosyl-(1->4)-beta-d-glucopyranosyl)-2-thioacetyl]aminoethyl]-1-naphthylamine-5-sulfonate thermotoga maritima 19.0 9.695 2 PMID:23627611 -3.2.1.4 p-nitrophenyl cellobiose pyrococcus horikoshii 0.41 0.41 3 PMID:17072684;PMID:17928686;PMID:18051592 -3.2.1.4 p-nitrophenyl-beta-d-cellobioside dickeya chrysanthemi 0.01 0.01 1 PMID:15287848 -3.2.1.4 p-nitrophenyl-beta-d-cellobioside pseudoalteromonas haloplanktis 0.18 0.18 1 PMID:15287848 -3.2.1.4 phosphoric acid swollen cellulose cellulomonas fimi 26100.0 15180.0 2 PMID:28982013 -3.2.1.4 raffinose trichoderma atroviride 0.092 0.092 1 PMID:28155168 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside alternaria sp. l1 3.07 3.07 1 PMID:27352363 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside aspergillus niger 10200.0 5100.474 2 PMID:29287324;PMID:35366188 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside aspergillus oryzae 1624.0 1352.0 2 PMID:28800907 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside aspergillus terreus 1065.0 407.6 5 PMID:28241810;PMID:29605638;PMID:34781207 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside bacteroides thetaiotaomicron 1743.29 906.545 2 PMID:29430381;PMID:30243237 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside caldicellulosiruptor bescii 51.9 51.9 1 PMID:31685873 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside dictyoglomus thermophilum 0.17 0.17 1 * -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside fusarium verticillioides 15.6 15.6 1 PMID:30476650 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside lactiplantibacillus plantarum 6.85 6.85 1 PMID:34780892 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside novosphingobium sp. pp1y 692.0 692.0 1 PMID:29678627 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside penicillium tardum 294.0 294.0 1 PMID:35670906 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside thermoclostridium stercorarium subsp. stercorarium 14.3 14.3 1 PMID:31685873 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside thermoclostridium stercorarium subsp. thermolacticum 650.0 650.0 1 PMID:37644729 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside thermotoga maritima 217.8 217.8 1 PMID:31685873 -3.2.1.40 4-nitrophenyl alpha-l-rhamnopyranoside thermotoga neapolitana 146.8 146.8 1 PMID:31685873 -3.2.1.40 baohuoside i aspergillus terreus 0.009 0.009 1 PMID:34781207 -3.2.1.40 hesperidin aspergillus niger 4.788 4.788 1 PMID:35366188 -3.2.1.40 hesperidin aspergillus oryzae 4986.0 3898.0 2 PMID:28800907;PMID:37818702 -3.2.1.40 hesperidin novosphingobium sp. pp1y 12.7 12.7 1 PMID:29678627 -3.2.1.40 icariin aspergillus terreus 0.094 0.094 1 PMID:34781207 -3.2.1.40 nairutin aspergillus oryzae 1208.0 1208.0 1 PMID:37818702 -3.2.1.40 naringin aspergillus niger 2.115 2.115 1 PMID:35366188 -3.2.1.40 naringin aspergillus oryzae 210.0 209.0 2 PMID:28800907;PMID:37818702 -3.2.1.40 naringin aspergillus tubingensis 48900.0 48900.0 1 PMID:30789260 -3.2.1.40 naringin novosphingobium sp. pp1y 214.0 214.0 1 PMID:29678627 -3.2.1.40 naringin penicillium tardum 336.0 336.0 1 PMID:35670906 -3.2.1.40 neohesperidin aspergillus oryzae 171.0 171.0 1 PMID:37818702 -3.2.1.40 quercitrin novosphingobium sp. pp1y 12.2 12.2 1 PMID:29678627 -3.2.1.40 rutin aspergillus niger 4.875 4.875 1 PMID:35366188 -3.2.1.40 rutin aspergillus oryzae 550.0 371.5 2 PMID:28800907;PMID:37818702 -3.2.1.40 rutin novosphingobium sp. pp1y 18.2 18.2 1 PMID:29678627 -3.2.1.41 alpha-cyclodextrin thermofilum pendens 0.09 0.09 1 PMID:29551507 -3.2.1.41 amylopectin oryza sativa 2.18 2.18 1 PMID:18787715 -3.2.1.41 amylopectin thermofilum pendens 1.69 1.69 1 PMID:29551507 -3.2.1.41 amylose thermofilum pendens 0.11 0.11 1 PMID:29551507 -3.2.1.41 beta-cyclodextrin thermofilum pendens 0.11 0.11 1 PMID:29551507 -3.2.1.41 beta-limit dextrin oryza sativa 3.31 3.31 1 PMID:18787715 -3.2.1.41 gamma-cyclodextrin thermofilum pendens 0.03 0.03 1 PMID:29551507 -3.2.1.41 pullulan anoxybacillus sp. wb42 128.4 109.95 2 PMID:29493906;PMID:31939086 -3.2.1.41 pullulan bacillus acidopullulyticus 977.3 977.3 1 PMID:30797482 -3.2.1.41 pullulan bacillus deramificans 3000.0 1749.5 2 PMID:27026175 -3.2.1.41 pullulan bacillus subtilis 79.0 41.31 2 PMID:16582490;PMID:33220368 -3.2.1.41 pullulan exiguobacterium sp. 37.0 37.0 1 PMID:26349928 -3.2.1.41 pullulan geobacillus stearothermophilus 2.23 2.23 1 PMID:37473696 -3.2.1.41 pullulan oryza sativa 23.1 23.1 1 PMID:18787715 -3.2.1.41 pullulan pullulanibacillus naganoensis 73.5 73.5 1 PMID:36536070 -3.2.1.41 pullulan pyrococcus yayanosii 43.01 43.01 1 PMID:35777517 -3.2.1.41 pullulan thermoanaerobacter thermohydrosulfuricus 271.0 271.0 1 PMID:3415657 -3.2.1.41 pullulan thermoanaerobacterium saccharolyticum 1828.0 1789.5 2 PMID:21750992 -3.2.1.41 pullulan thermoanaerobium sp. 4830.0 4830.0 1 * -3.2.1.41 pullulan thermofilum pendens 0.73 0.73 1 PMID:29551507 -3.2.1.41 soluble starch oryza sativa 2.89 2.89 1 PMID:18787715 -3.2.1.41 soluble starch thermoanaerobacterium saccharolyticum 877.9 726.3 2 PMID:21750992 -3.2.1.41 starch thermofilum pendens 1.67 1.67 1 PMID:29551507 -3.2.1.45 (6-[n-(7-nitrobenz-2-oxa-1,3 diazol-4-yl)amino]hexanoyl)-beta-d-galactosylceramide homo sapiens 0.03 0.03 1 PMID:17595169 -3.2.1.45 (6-[n-(7-nitrobenz-2-oxa-1,3 diazol-4-yl)amino]hexanoyl)-beta-d-glucosylceramide homo sapiens 0.12 0.12 1 PMID:17595169 -3.2.1.45 2,4-dinitrophenyl beta-d-glucopyranoside paenibacillus sp. 470.0 470.0 1 PMID:14561218 -3.2.1.45 4-methylumbelliferyl-beta-d-galactopyranoside homo sapiens 1.57 1.57 1 PMID:17595169 -3.2.1.45 4-methylumbelliferyl-beta-d-glucopyranoside homo sapiens 1.23 1.23 1 PMID:17595169 -3.2.1.45 4-nitrophenyl beta-d-galactoside thermoanaerobacterium xylanolyticum 255.0 255.0 1 PMID:27115290 -3.2.1.45 4-nitrophenyl beta-d-glucopyranoside oryza sativa 285.1 285.1 1 PMID:34563538 -3.2.1.45 4-nitrophenyl beta-d-glucoside thermoanaerobacterium xylanolyticum 49.0 43.3 2 PMID:27115290 -3.2.1.45 c18-glucosylceramide homo sapiens 0.007 0.007 1 PMID:17595169 -3.2.1.45 c6-nbd-glucer oryza sativa 0.121 0.121 1 PMID:34563538 -3.2.1.45 cellobiose thermoanaerobacterium xylanolyticum 44.4 44.4 1 PMID:27115290 -3.2.1.45 d18:1(4e)-c12:0-glucer oryza sativa 121.1 121.1 1 PMID:34563538 -3.2.1.45 d18:1(4e)-c18:0-glucer oryza sativa 0.0072 0.0072 1 PMID:34563538 -3.2.1.45 d18:1(4e)-c8:0-glucer oryza sativa 156.1 156.1 1 PMID:34563538 -3.2.1.45 d18:2(4e,8e)-c16h:0-glucer oryza sativa 145.8 145.8 1 PMID:34563538 -3.2.1.45 d18:2(4e,8z)-c16h:0-glucer oryza sativa 115.8 115.8 1 PMID:34563538 -3.2.1.45 d19:2(4e,8e,9me)-c16h:1-glucer oryza sativa 151.0 151.0 1 PMID:34563538 -3.2.1.45 d19:2(4e,8e,9me)-c18h:1-glucer oryza sativa 144.6 144.6 1 PMID:34563538 -3.2.1.45 glucosylceramide homo sapiens 35.0 33.335 2 PMID:19741058 -3.2.1.45 laminaribiose thermoanaerobacterium xylanolyticum 41.4 41.4 1 PMID:27115290 -3.2.1.45 n-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-d-erythro-sphingosine arabidopsis thaliana 0.008 0.008 1 PMID:31819005 -3.2.1.45 n-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-d-glucosyl-beta1-10-sphingosine oryza sativa 112.1 112.1 1 PMID:34563538 -3.2.1.45 p-nitrophenyl beta-d-glucopyranoside paenibacillus sp. 560.0 560.0 1 PMID:14561218 -3.2.1.48 4-nitrophenyl alpha-d-glucopyranoside pyrococcus furiosus 21.9 21.9 1 PMID:18156337 -3.2.1.48 4-nitrophenyl-alpha-d-glucoside homo sapiens 17.0 17.0 1 PMID:20356844 -3.2.1.48 isomaltose homo sapiens 97.0 97.0 1 PMID:20356844 -3.2.1.48 isomaltose pyrococcus furiosus 58.8 58.8 1 PMID:18156337 -3.2.1.48 maltose homo sapiens 137.0 137.0 1 PMID:20356844 -3.2.1.48 maltose pyrococcus furiosus 1600.0 1600.0 1 PMID:18156337 -3.2.1.48 panose pyrococcus furiosus 278.0 278.0 1 PMID:18156337 -3.2.1.48 sucrose xanthomonas axonopodis 66.45 66.45 1 PMID:18565544 -3.2.1.48 sucrose xanthomonas campestris pv. campestris 21.7 21.7 1 PMID:19966417 -3.2.1.49 4-nitrophenyl alpha-d-n-acetylgalactosaminide homo sapiens 16.3 16.3 1 PMID:19683538 -3.2.1.49 4-nitrophenyl alpha-n-acetylgalactosaminide enterococcus faecalis 6.54 6.54 1 PMID:34826537 -3.2.1.49 4-nitrophenyl n-acetyl-alpha-d-galactosamine elizabethkingia meningoseptica 19.7 19.7 1 * -3.2.1.49 4-nitrophenyl n-acetyl-alpha-d-galactosaminide bacteroides caccae 3.6 3.6 1 PMID:31530641 -3.2.1.49 4-nitrophenyl n-acetyl-alpha-d-galactosaminide phocaeicola plebeius 7.2 7.2 1 PMID:31530641 -3.2.1.49 4-nitrophenyl n-acetyl-alpha-d-galactosaminide phocaeicola vulgatus 0.25 0.25 1 PMID:31530641 -3.2.1.49 4-nitrophenyl n-acetyl-alpha-d-galactosaminide spirosoma linguale 173.0 143.5 6 PMID:31186954 -3.2.1.49 4-nitrophenyl n-acetyl-d-galactosamine homo sapiens 0.0258 0.0258 1 PMID:29748462;PMID:30388774 -3.2.1.49 galnac-alpha-pnp bacteroides caccae 3.6 2.85 2 PMID:31530641 -3.2.1.49 galnac-alpha-pnp phocaeicola plebeius 7.2 4.71 2 PMID:31530641 -3.2.1.50 2,4-dinitrophenyl-alpha-n-acetyl-d-glucosaminide clostridium perfringens 8.5 8.5 1 PMID:18443291 -3.2.1.50 4-methylumbelliferyl n-acetyl-alpha-d-glucosaminide bacteroides thetaiotaomicron 3.68 3.68 1 PMID:34165649 -3.2.1.50 4-nitrophenyl n-acetyl-alpha-d-glucosaminopyranoside clostridium perfringens 0.26 0.26 1 PMID:18443291 -3.2.1.50 4-nitrophenyl-n-acetyl-alpha-d-glucosaminide clostridium perfringens 0.69 0.69 1 PMID:21177247 -3.2.1.50 n-acetyl-alpha-d-gluc-1,4-(1-methoxyphenyl)gal clostridium perfringens 1.24 1.24 1 PMID:21177247 -3.2.1.50 n-acetyl-alpha-d-glucose-(1->4)-beta-d-glucuronic acid-1-propylamine-n-fmoc bacteroides thetaiotaomicron 3.57 3.57 1 PMID:34165649 -3.2.1.51 2-deoxy-2-fluoro-alpha-l-fucosyl fluoride thermotoga maritima 0.047 0.047 1 PMID:12975375 -3.2.1.51 4-methylumbelliferyl alpha-l-fucopyranoside lamellidens corrianus 1.01 1.01 1 PMID:28610928 -3.2.1.51 4-nitrophenyl alpha-l-fucopyranoside fusarium proliferatum 39.8 39.8 1 PMID:27984201 -3.2.1.51 4-nitrophenyl alpha-l-fucopyranoside homo sapiens 9.96 9.96 1 PMID:35907402 -3.2.1.51 4-nitrophenyl alpha-l-fucopyranoside lacticaseibacillus rhamnosus 1022.7 99.9 3 PMID:36370158 -3.2.1.51 4-nitrophenyl alpha-l-fucopyranoside paenibacillus thiaminolyticus 111.0 105.0 2 PMID:26013545;PMID:35113503 -3.2.1.51 4-nitrophenyl alpha-l-fucopyranoside thermotoga maritima 363.3 193.75 2 PMID:33938983 -3.2.1.51 4-nitrophenyl alpha-l-fucoside bombyx mori 12.5 12.5 1 PMID:32561391 -3.2.1.51 4-nitrophenyl alpha-l-fucoside thermotoga maritima 35.0 20.05 2 PMID:17240986 -3.2.1.51 4-nitrophenyl-alpha-l-fucopyranoside emticicia oligotrophica 3.73 3.61 3 PMID:26941394 -3.2.1.51 4-nitrophenyl-alpha-l-fucopyranoside saccharolobus solfataricus 430.0 287.0 5 PMID:15835922;PMID:17687508 -3.2.1.51 4-nitrophenyl-alpha-l-fucopyranoside thermotoga maritima 35.0 20.05 2 PMID:17240986 -3.2.1.51 4-nitrophenyl-alpha-l-fucoside saccharolobus solfataricus 287.0 287.0 1 PMID:16920738 -3.2.1.51 alpha-l-fucopyranosyl-(1->2)-d-galactopyranose clostridium perfringens 15.4 15.4 1 PMID:26663202 -3.2.1.51 alpha-l-fucosyl fluoride thermotoga maritima 7.6 5.25 2 PMID:12975375;PMID:14715651 -3.2.1.51 beta-d-gal-(1->3)-[alpha-l-fuc-(1->4)]-d-glcnac clostridium perfringens 26.9 26.9 1 PMID:26663202 -3.2.1.51 beta-d-gal-(1->4)-[alpha-l-fuc-(1->3)]-d-glcnac clostridium perfringens 23.6 23.6 1 PMID:26663202 -3.2.1.51 fuc-alpha-1,2-gal homo sapiens 0.74 0.74 1 PMID:35907402 -3.2.1.51 p-nitrophenyl alpha-l-fucopyranoside homo sapiens 17.1 17.1 1 PMID:19072333 -3.2.1.51 p-nitrophenyl alpha-l-fucoside saccharolobus solfataricus 287.0 266.0 2 PMID:12569098;PMID:12911294 -3.2.1.51 p-nitrophenyl alpha-l-fucoside thermotoga maritima 14.3 9.1 3 PMID:12975375;PMID:14715651 -3.2.1.52 (n-acetyl-beta-d-glucosamine)2 bombyx mori 1010.0 620.0 3 * -3.2.1.52 (n-acetyl-beta-d-glucosamine)2 penaeus japonicus 298.0 298.0 1 PMID:9063965 -3.2.1.52 (n-acetyl-beta-d-glucosamine)3 bombyx mori 209.0 130.0 3 * -3.2.1.52 (n-acetyl-beta-d-glucosamine)3 penaeus japonicus 96.4 96.4 1 PMID:9063965 -3.2.1.52 (n-acetyl-beta-d-glucosamine)4 bombyx mori 129.0 110.0 3 * -3.2.1.52 (n-acetyl-beta-d-glucosamine)4 penaeus japonicus 30.1 30.1 1 PMID:9063965 -3.2.1.52 (n-acetyl-beta-d-glucosamine)5 bombyx mori 76.0 75.6 3 * -3.2.1.52 (n-acetyl-beta-d-glucosamine)5 penaeus japonicus 14.7 14.7 1 PMID:9063965 -3.2.1.52 (n-acetyl-beta-d-glucosamine)6 bombyx mori 55.0 51.9 3 * -3.2.1.52 (n-acetyl-beta-d-glucosamine)6 penaeus japonicus 8.3 8.3 1 PMID:9063965 -3.2.1.52 2,4-dinitrophenyl-n-acetyl-beta-d-glucosaminide aspergillus niger 38.3 38.3 1 PMID:7440573 -3.2.1.52 3-fluoro-4-nitrophenyl n-acetyl-beta-d-galactosaminide homo sapiens 2.03 2.03 1 PMID:27149221 -3.2.1.52 3-fluoro-4-nitrophenyl n-acetyl-beta-d-glucosaminide homo sapiens 1.54 1.54 1 PMID:27149221 -3.2.1.52 4-methylumbelliferyl beta-d-glucopyranoside saccharolobus solfataricus 8.8 8.8 1 PMID:24060745 -3.2.1.52 4-methylumbelliferyl n-acetyl-beta-d-glucosamine aggregatibacter actinomycetemcomitans 0.0235 0.0235 1 PMID:17949435 -3.2.1.52 4-methylumbelliferyl n-acetyl-beta-d-glucosamine penicillium oxalicum 43.0 43.0 1 PMID:21564548 -3.2.1.52 4-methylumbelliferyl n-acetyl-beta-d-glucosaminide ostrinia furnacalis 434.7 434.7 1 PMID:21106526 -3.2.1.52 4-methylumbelliferyl n-acetyl-beta-d-glucosaminide saccharolobus solfataricus 5.4 5.4 1 PMID:24060745 -3.2.1.52 4-nitrophenyl 2-acetamido-2-deoxy-beta-d-galactopyranoside penicillium oxalicum 723.0 723.0 1 PMID:21564548 -3.2.1.52 4-nitrophenyl 2-acetamido-2-deoxy-beta-d-glucopyranoside penicillium oxalicum 347.0 347.0 1 PMID:21564548 -3.2.1.52 4-nitrophenyl 2-deoxy-2-difluoroacetamido-beta-d-galactopyranoside homo sapiens 0.27 0.27 1 PMID:27149221 -3.2.1.52 4-nitrophenyl 2-deoxy-2-fluoroacetamido-beta-d-galactopyranoside homo sapiens 2.6 2.6 1 PMID:27149221 -3.2.1.52 4-nitrophenyl 2-deoxy-2-trifluoroacetamido-beta-d-galactopyranoside homo sapiens 0.042 0.042 1 PMID:27149221 -3.2.1.52 4-nitrophenyl beta-d-glucopyranoside saccharolobus solfataricus 9.15 9.15 1 PMID:24060745 -3.2.1.52 4-nitrophenyl beta-n-acetyl-d-galactosaminide cellulomonas fimi 129.0 129.0 1 PMID:16762038 -3.2.1.52 4-nitrophenyl beta-n-acetyl-d-galactosaminide ostrinia furnacalis 766.0 766.0 1 PMID:18959754 -3.2.1.52 4-nitrophenyl beta-n-acetyl-d-glucosaminide akkermansia muciniphila 51.39 51.39 1 PMID:32819592 -3.2.1.52 4-nitrophenyl beta-n-acetyl-d-glucosaminide cellulomonas fimi 0.18 0.18 1 PMID:16762038 -3.2.1.52 4-nitrophenyl beta-n-acetyl-d-glucosaminide saccharolobus solfataricus 19.2 19.2 1 PMID:24060745 -3.2.1.52 4-nitrophenyl di-n-acetyl-beta-d-chitobiose thermotoga maritima msb8 199.0 199.0 1 PMID:19914575 -3.2.1.52 4-nitrophenyl di-n-acetyl-beta-d-chitobiose thermotoga neapolitana 220.8 220.8 1 PMID:19914575 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-galactosaminide homo sapiens 1.32 1.32 1 PMID:27149221 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-galactosaminide stackebrandtia nassauensis 0.71 0.71 1 PMID:30871033 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-glucosamine aggregatibacter actinomycetemcomitans 6.08 3.5035 2 PMID:17949435 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-glucosamine lactococcus lactis 26.7 26.7 1 PMID:22356128 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-glucosamine thermotoga maritima msb8 246.2 246.2 1 PMID:19914575 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-glucosamine thermotoga neapolitana 273.4 273.4 1 PMID:19914575 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-glucosaminide aspergillus versicolor 35.3 21.715 2 PMID:30603849 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-glucosaminide caldicellulosiruptor acetigenus 127.89 127.89 1 PMID:34627844 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-glucosaminide chitinibacter sp. gc72 4667.1 4667.1 1 PMID:35620090 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-glucosaminide homo sapiens 0.51 0.51 1 PMID:27149221 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-glucosaminide saccharolobus solfataricus 19.2 19.2 1 PMID:24060745 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-glucosaminide stackebrandtia nassauensis 0.92 0.92 1 PMID:30871033 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-glucosaminide streptococcus pneumoniae 11.0 4.8 5 PMID:22013074 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-glucosaminide uncultured actinomycetales bacterium 19.4 19.4 1 PMID:29911342 -3.2.1.52 4-nitrophenyl n-acetyl-beta-d-glucosaminide uncultured bacteroidota bacterium 11.6 11.6 1 PMID:29911342 -3.2.1.52 4-nitrophenyl tri-n-acetyl-beta-d-chitotriose thermotoga maritima msb8 146.7 146.7 1 PMID:19914575 -3.2.1.52 4-nitrophenyl tri-n-acetyl-beta-d-chitotriose thermotoga neapolitana 147.2 147.2 1 PMID:19914575 -3.2.1.52 4-nitrophenyl-2-(acetamino)-2-deoxy-beta-d-glucopyranoside palythoa caribaeorum 0.61 0.61 1 PMID:18171621 -3.2.1.52 4-nitrophenyl-beta-n-acetyl-d-glucosaminide cellulomonas fimi 482.0 482.0 1 PMID:16762038 -3.2.1.52 4-nitrophenyl-beta-n-acetyl-d-glucosaminide ostrinia furnacalis 708.0 708.0 1 PMID:18959754 -3.2.1.52 4-nitrophenyl-n-acetyl-beta-d-glucosaminide akkermansia muciniphila 5.57 5.57 1 PMID:31345574 -3.2.1.52 chitobiose ostrinia furnacalis 507.0 507.0 1 PMID:21106526 -3.2.1.52 glcnacbeta(1-2)manalpha(1-6)[glcnacbeta(1-2)manalpha(1-3)]manbeta(1-4)glcnacbeta(1-4)glcnac-2-pyridylaminoside spodoptera frugiperda 0.0025 0.0015 2 PMID:16684772 -3.2.1.52 glcnacbeta(1-2)manalpha(1-6)[manalpha(1-3)]manbeta(1-4)glcnacbeta(1-4)glcnac-2-pyridylaminoside spodoptera frugiperda 0.0007 0.0007 1 PMID:16684772 -3.2.1.52 glcnacbeta(1-4)glcnac ostrinia furnacalis 934.0 934.0 1 PMID:18959754 -3.2.1.52 manalpha(1-6)[glcnacbeta(1-2)manalpha(1-3)]manbeta(1-4)glcnacbeta(1-4)glcnac-2-pyridylaminoside spodoptera frugiperda 0.0016 0.0016 1 PMID:16684772 -3.2.1.52 manalpha(1-6)[manalpha(1-3)]manalpha(1-6)[glcnacbeta(1-2)manalpha(1-3)]manbeta(1-4)glcnacbeta(1-4)glcnac-2-pyridylaminoside spodoptera frugiperda 0.0012 0.0012 1 PMID:16684772 -3.2.1.52 n,n-diacetylchitobiose cupiennius salei 28.5 28.5 1 PMID:7370275 -3.2.1.52 n-acetylglucosaminyl-beta-1,2-man streptococcus pneumoniae 0.46 0.1 3 PMID:22013074 -3.2.1.52 p-nitrophenyl-beta-2-acetamido-2-deoxy-d-galactopyranoside aspergillus niger 110.0 110.0 1 PMID:7440573 -3.2.1.52 p-nitrophenyl-beta-2-acetamido-2-deoxy-d-galactopyranoside bombyx mori 1150.0 570.0 3 * -3.2.1.52 p-nitrophenyl-beta-2-acetamido-2-deoxy-d-galactopyranoside cupiennius salei 2.8 2.8 1 PMID:7370275 -3.2.1.52 p-nitrophenyl-beta-2-acetamido-2-deoxy-d-galactopyranoside rattus norvegicus 1.58 1.1800000000000002 6 PMID:1482400 -3.2.1.52 p-nitrophenyl-beta-2-acetamido-2-deoxy-d-glucopyranoside aspergillus niger 187.0 0.0212 3 PMID:7440573 -3.2.1.52 p-nitrophenyl-beta-2-acetamido-2-deoxy-d-glucopyranoside bombyx mori 890.0 820.0 3 * -3.2.1.52 p-nitrophenyl-beta-2-acetamido-2-deoxy-d-glucopyranoside cupiennius salei 30.2 30.2 1 PMID:7370275 -3.2.1.52 p-nitrophenyl-beta-2-acetamido-2-deoxy-d-glucopyranoside penaeus japonicus 598.0 598.0 1 PMID:9063965 -3.2.1.52 p-nitrophenyl-beta-2-acetamido-2-deoxy-d-glucopyranoside rattus norvegicus 2.66 1.7799999999999998 6 PMID:1482400 -3.2.1.52 p-nitrophenyl-n-acetyl-beta-d-glalactosamine oryza sativa 7500.0 7500.0 1 PMID:12297015 -3.2.1.52 p-nitrophenyl-n-acetyl-beta-d-glucosaminide oryza sativa 79830.0 79830.0 1 PMID:12297015 -3.2.1.52 p-nitrophenyl-thio-beta-n-acetyl-d-glucosaminide aspergillus niger 2.83 2.83 1 PMID:7440573 -3.2.1.53 4-nitrophenyl beta-n-acetylgalactosaminide paenibacillus sp. 7.3 7.3 1 PMID:21297160 -3.2.1.54 acarbose pyrococcus furiosus 228.0 228.0 2 PMID:15466542 -3.2.1.54 alpha-cyclodextrin anoxybacillus flavithermus 580.0 562.5 2 PMID:16310726;PMID:31955121 -3.2.1.54 alpha-cyclodextrin anoxybacillus flavithermus subsp. flavithermus 580.0 580.0 2 PMID:31615670 -3.2.1.54 alpha-cyclodextrin flavobacterium sp. 92 40.9 40.9 1 PMID:19014948 -3.2.1.54 alpha-cyclodextrin geobacillus thermopakistaniensis 2739.0 2739.0 1 PMID:31212108 -3.2.1.54 alpha-cyclodextrin laceyella sacchari 46.1 46.1 1 PMID:16310726 -3.2.1.54 alpha-cyclodextrin paenibacillus sp. 800.0 412.5 2 PMID:15469727 -3.2.1.54 alpha-cyclodextrin palaeococcus pacificus 1.375 1.375 1 PMID:31622540 -3.2.1.54 alpha-cyclodextrin pyrococcus furiosus 241.0 241.0 2 PMID:15466542 -3.2.1.54 amylopectin bacillus sp. (in: firmicutes) 50.36 25.275 2 PMID:16536613 -3.2.1.54 amylose anoxybacillus flavithermus 13.4 13.4 1 PMID:16310726 -3.2.1.54 amylose bacillus sp. (in: firmicutes) 22.11 15.055 2 PMID:16536613 -3.2.1.54 amylose laceyella sacchari 23.0 23.0 1 PMID:16310726 -3.2.1.54 beta-cyclodextrin anoxybacillus flavithermus 382.0 348.5 2 PMID:16310726;PMID:31955121 -3.2.1.54 beta-cyclodextrin anoxybacillus flavithermus subsp. flavithermus 382.0 382.0 2 PMID:31615670 -3.2.1.54 beta-cyclodextrin bacillus sp. (in: firmicutes) 78.2 8.5 3 PMID:16367752 -3.2.1.54 beta-cyclodextrin flavobacterium sp. 92 26.5 26.5 1 PMID:19014948 -3.2.1.54 beta-cyclodextrin geobacillus thermopakistaniensis 1678.0 1678.0 1 PMID:31212108 -3.2.1.54 beta-cyclodextrin laceyella sacchari 73.7 37.95 2 PMID:16310726 -3.2.1.54 beta-cyclodextrin massilia timonae 138.8 138.8 1 PMID:30149121 -3.2.1.54 beta-cyclodextrin paenibacillus sp. 2044.0 1040.35 2 PMID:15469727 -3.2.1.54 beta-cyclodextrin palaeococcus pacificus 1.17 1.17 1 PMID:31622540 -3.2.1.54 beta-cyclodextrin pyrococcus furiosus 610.0 289.0 4 PMID:15466542;PMID:17630303;PMID:22902546 -3.2.1.54 beta-cyclomaltodextrin bacillus sp. (in: firmicutes) 1.68 1.19 2 PMID:11923309 -3.2.1.54 cyclomaltoheptaose bacillus sp. (in: firmicutes) 78.18 40.59 2 PMID:16536613 -3.2.1.54 gamma-cyclodextrin anoxybacillus flavithermus 308.0 308.0 1 PMID:31955121 -3.2.1.54 gamma-cyclodextrin anoxybacillus flavithermus subsp. flavithermus 308.0 308.0 2 PMID:31615670 -3.2.1.54 gamma-cyclodextrin evansella clarkii 3100.0 3100.0 1 PMID:18824139 -3.2.1.54 gamma-cyclodextrin flavobacterium sp. 92 17.4 17.4 1 PMID:19014948 -3.2.1.54 gamma-cyclodextrin geobacillus thermopakistaniensis 821.0 821.0 1 PMID:31212108 -3.2.1.54 gamma-cyclodextrin paenibacillus sp. 1155.0 590.85 2 PMID:15469727 -3.2.1.54 gamma-cyclodextrin palaeococcus pacificus 0.81 0.81 1 PMID:31622540 -3.2.1.54 gamma-cyclodextrin pyrococcus furiosus 173.0 173.0 2 PMID:15466542 -3.2.1.54 maltoheptaose pyrococcus furiosus 160.0 126.65 2 PMID:17630303;PMID:22902546 -3.2.1.54 maltooctaose evansella clarkii 0.03 0.03 1 PMID:18824139 -3.2.1.54 maltotriose pyrococcus furiosus 268.0 268.0 2 PMID:15466542 -3.2.1.54 pullulan anoxybacillus flavithermus 3.6 3.6 1 PMID:16310726 -3.2.1.54 pullulan laceyella sacchari 42.6 42.6 1 PMID:16310726 -3.2.1.54 pullulan thermoactinomyces vulgaris 140.0 140.0 1 PMID:15182368 -3.2.1.54 soluble starch anoxybacillus flavithermus 16.9 16.9 1 PMID:16310726 -3.2.1.54 soluble starch laceyella sacchari 36.8 36.8 1 PMID:16310726 -3.2.1.54 starch pyrococcus furiosus 67.0 67.0 1 PMID:15466542 -3.2.1.54 starch thermoactinomyces vulgaris 120.0 120.0 1 PMID:15182368 -3.2.1.55 1,5-alpha-l-arabinobiose bacillus subtilis 32.0 32.0 1 PMID:18757805 -3.2.1.55 1,5-alpha-l-arabinobiose levilactobacillus brevis 71.0 71.0 1 PMID:28485897 -3.2.1.55 1,5-alpha-l-arabinobiose weissella sp. 142 221.0 221.0 1 PMID:28485897 -3.2.1.55 1,5-alpha-l-arabinotriose bacillus subtilis 88.0 44.375 2 PMID:18757805 -3.2.1.55 1,5-alpha-l-arabinotriose levilactobacillus brevis 57.0 57.0 1 PMID:28485897 -3.2.1.55 1,5-alpha-l-arabinotriose weissella sp. 142 125.0 125.0 1 PMID:28485897 -3.2.1.55 2',4',6'-trichlorophenyl alpha-l-arabinofuranoside geobacillus stearothermophilus 65.0 65.0 1 PMID:12221104 -3.2.1.55 2',5'-dinitrophenyl alpha-l-arabinofuranoside geobacillus stearothermophilus 190.0 190.0 1 PMID:12221104 -3.2.1.55 2,3-di-alpha-l-arabinofuranosyl xylotriose acetivibrio clariflavus 15.9 15.9 1 PMID:30903213 -3.2.1.55 2,5-dinitrophenyl-alpha-l-arabinofuranoside trichoderma koningii 8.25 8.25 1 PMID:17002602 -3.2.1.55 2-alpha-l-arabinofuranosyl xylotriose acetivibrio clariflavus 55.2 55.2 1 PMID:30903213 -3.2.1.55 2-alpha-l-arabinofuranosyl-xylotriose trametes hirsuta 51.69 51.69 1 PMID:37178306 -3.2.1.55 3',4'-dinitrophenyl alpha-l-arabinofuranoside geobacillus stearothermophilus 340.0 340.0 1 PMID:12221104 -3.2.1.55 3-alpha-l-arabinofuranosyl xylobiose acetivibrio clariflavus 743.9 743.9 1 PMID:30903213 -3.2.1.55 3-alpha-l-arabinofuranosyl-xylobiose trametes hirsuta 183.4 183.4 1 PMID:37178306 -3.2.1.55 3-alpha-l-arabinofuranosyl-xylotetraose trametes hirsuta 21.94 21.94 1 PMID:37178306 -3.2.1.55 3-nitrophenyl-alpha-l-arabinofuranoside geobacillus stearothermophilus 83.0 83.0 1 PMID:12221104 -3.2.1.55 4-chloro-2-nitrophenyl-alpha-l-arabinofuranoside trichoderma koningii 6.52 3.5349999999999997 2 PMID:17002602 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside alicyclobacillus sp. 23.0 23.0 1 PMID:26628911 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside bacillus subtilis 108.9 108.9 1 PMID:33808840 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside caldicellulosiruptor saccharolyticus 285.0 255.5 2 PMID:20477891 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside caldicellulosiruptor sp. f32 3900.0 3900.0 1 PMID:28432102 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside corynebacterium alkanolyticum 149.8 106.35000000000001 2 PMID:28409383 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside evansstolkia leycettana 1600.0 1600.0 1 PMID:31426823 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside paenibacillus sp. 328.0 328.0 1 PMID:27398094 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside penicillium oxalicum 0.27 0.27 1 PMID:29611040 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside penicillium subrubescens 1169.1 506.4 9 PMID:35014696 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside pleurotus ostreatus 50.0 50.0 1 PMID:25471797 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside pseudothermotoga thermarum 151.0 151.0 1 PMID:26725313 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside streptomyces avermitilis 0.11 0.11 1 PMID:20739278 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside talaromyces amestolkiae 0.41 0.22999999999999998 2 PMID:37569374 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside talaromyces purpureogenus 2.73 2.415 2 PMID:20562284;PMID:26058539 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside thermobacillus xylanilyticus 139.0 139.0 1 * -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside thermomyces dupontii 14.3 14.3 1 * -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside thermothielavioides terrestris 6.8 6.8 1 PMID:32866628 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside trametes hirsuta 8.45 8.45 1 PMID:37178306 -3.2.1.55 4-nitrophenyl alpha-l-arabinofuranoside uncultured rumen bacterium 5.6 5.6 1 PMID:21720773 -3.2.1.55 4-nitrophenyl alpha-l-arabinopyranoside acetivibrio clariflavus 631.4 631.4 1 PMID:30903213 -3.2.1.55 4-nitrophenyl beta-d-galactofuranoside paenibacillus sp. 327.0 327.0 1 PMID:27398094 -3.2.1.55 4-nitrophenyl beta-d-galactofuranoside talaromyces purpureogenus 1.0 1.0 1 PMID:26058539 -3.2.1.55 4-nitrophenyl beta-d-glucopyranoside pleurotus ostreatus 0.38 0.38 1 PMID:25471797 -3.2.1.55 4-nitrophenyl beta-d-xylopyranoside paenibacillus sp. 10.6 10.6 1 PMID:27398094 -3.2.1.55 4-nitrophenyl-alpha-l-arabinofuranoside acetivibrio thermocellus 4.78 4.75 2 PMID:24039988 -3.2.1.55 4-nitrophenyl-alpha-l-arabinofuranoside geobacillus stearothermophilus 87.0 87.0 1 PMID:12221104 -3.2.1.55 4-nitrophenyl-alpha-l-arabinofuranoside mycosarcoma maydis 0.039 0.039 1 PMID:24394409 -3.2.1.55 4-nitrophenyl-alpha-l-arabinofuranoside penicillium chrysogenum 59.3 36.8 2 PMID:12726996 -3.2.1.55 4-nitrophenyl-alpha-l-arabinofuranoside pleurotus ostreatus 50.17 50.17 1 PMID:22080345 -3.2.1.55 4-nitrophenyl-alpha-l-arabinofuranoside podospora anserina 0.38 0.38 1 PMID:24394409 -3.2.1.55 4-nitrophenyl-alpha-l-arabinofuranoside streptomyces coelicolor 0.02 0.02 1 PMID:24482228 -3.2.1.55 4-nitrophenyl-alpha-l-arabinofuranoside thermobacillus xylanilyticus 4100.0 2337.5 2 PMID:11842234;PMID:22823427 -3.2.1.55 4-nitrophenyl-alpha-l-arabinopyranoside acetivibrio thermocellus 3.53 3.5149999999999997 2 PMID:24039988 -3.2.1.55 4-nitrophenyl-beta-d-glucopyranoside pleurotus ostreatus 0.155 0.155 1 PMID:22080345 -3.2.1.55 alpha-1,3-arabinoxylobiose acetivibrio thermocellus 8.6 8.6 1 PMID:16336192 -3.2.1.55 alpha-1,5-arabinotriose acetivibrio thermocellus 4.6 4.6 1 PMID:16336192 -3.2.1.55 alpha-1,5-l-arabinohexaose fusarium graminearum 94000.0 94000.0 1 PMID:19269961 -3.2.1.55 alpha-1,5-l-arabinopentaose fusarium graminearum 81000.0 81000.0 1 PMID:19269961 -3.2.1.55 alpha-1,5-l-arabinotetraose fusarium graminearum 105000.0 105000.0 1 PMID:19269961 -3.2.1.55 alpha-1,5-l-arabinotriose fusarium graminearum 113000.0 113000.0 1 PMID:19269961 -3.2.1.55 arabinan talaromyces amestolkiae 0.23 0.21500000000000002 2 PMID:37569374 -3.2.1.55 arabinan trametes hirsuta 0.35 0.35 1 PMID:37178306 -3.2.1.55 arabinoxylan talaromyces amestolkiae 37.17 27.03 2 PMID:37569374 -3.2.1.55 arabinoxylan trametes hirsuta 0.014 0.014 1 PMID:37178306 -3.2.1.55 beechwood xylan acetivibrio thermocellus 0.47 0.44999999999999996 2 PMID:24039988 -3.2.1.55 birchwood xylan acetivibrio thermocellus 0.48 0.46499999999999997 2 PMID:24039988 -3.2.1.55 ginsenoside rc bacillus subtilis 79.1 79.1 1 PMID:33808840 -3.2.1.55 insoluble wheat arabinoxylan acetivibrio thermocellus 1.05 1.0350000000000001 2 PMID:24039988 -3.2.1.55 larch type ii arabinogalactan bifidobacterium longum subsp. longum 220.0 220.0 1 PMID:30564851 -3.2.1.55 linear alpha-1,5-l-arabinan bacillus subtilis 12.0 12.0 1 PMID:18757805 -3.2.1.55 m-nitrophenyl-alpha-l-arabinofuranoside trichoderma koningii 2.02 2.02 1 PMID:17002602 -3.2.1.55 oat spelt xylan acetivibrio thermocellus 1.12 1.1 2 PMID:24039988 -3.2.1.55 p-cyanophenyl-alpha-l-arabinofuranoside trichoderma koningii 1.7 1.7 1 PMID:17002602 -3.2.1.55 p-nitrophenyl-alpha-l-arabinofuranose thermobacillus xylanilyticus 355.0 355.0 1 PMID:18563919 -3.2.1.55 p-nitrophenyl-alpha-l-arabinofuranoside acetivibrio thermocellus 103.0 103.0 1 PMID:16336192 -3.2.1.55 p-nitrophenyl-alpha-l-arabinofuranoside arabidopsis thaliana 1.36 1.36 1 PMID:16798843 -3.2.1.55 p-nitrophenyl-alpha-l-arabinofuranoside aspergillus luchuensis 0.099 0.099 1 PMID:16784813 -3.2.1.55 p-nitrophenyl-alpha-l-arabinofuranoside bacillus subtilis 306.0 300.5 2 PMID:18757805 -3.2.1.55 p-nitrophenyl-alpha-l-arabinofuranoside selenomonas ruminantium 2.68 2.68 1 PMID:17689155 -3.2.1.55 p-nitrophenyl-alpha-l-arabinofuranoside talaromyces purpureogenus 2.45 2.45 1 PMID:18550352 -3.2.1.55 p-nitrophenyl-alpha-l-arabinofuranoside trichoderma koningii 21.0 11.92 2 PMID:17002602 -3.2.1.55 phenyl-alpha-l-arabinofuranoside trichoderma koningii 1.23 1.23 1 PMID:17002602 -3.2.1.55 rye arabinoxylan acetivibrio thermocellus 4.97 4.835 2 PMID:24039988 -3.2.1.55 rye arabinoxylan aspergillus nidulans 354.17 354.17 1 PMID:28890404 -3.2.1.55 rye arabinoxylan penicillium parvum 44.5 44.5 1 PMID:34933174 -3.2.1.55 rye arabinoxylan talaromyces funiculosus 1.11 1.0175 2 PMID:24034435 -3.2.1.55 soluble wheat arabinoxylan acetivibrio thermocellus 3.48 3.34 2 PMID:24039988 -3.2.1.55 wheat arabinoxylan acetivibrio thermocellus 0.07 0.07 1 PMID:16336192 -3.2.1.55 wheat arabinoxylan aspergillus nidulans 361.74 361.74 1 PMID:28890404 -3.2.1.55 wheat arabinoxylan penicillium parvum 57.8 57.8 1 PMID:34933174 -3.2.1.55 wheat arabinoxylan talaromyces funiculosus 1.2 0.99 3 PMID:24034435 -3.2.1.55 wheat l-arabinoxylan streptomyces coelicolor 0.3 0.3 1 PMID:24482228 -3.2.1.57 panose aspergillus niger 180.0 180.0 1 PMID:15560783 -3.2.1.58 4-nitrophenyl beta-d-glucopyranoside rhizomucor miehei 0.071 0.071 1 PMID:25577102 -3.2.1.58 4-nitrophenyl beta-d-glucopyranoside uncultured bacterium 131.1 131.1 1 PMID:33375982 -3.2.1.58 4-nitrophenyl beta-d-xylopyranoside uncultured bacterium 28.7 28.7 1 PMID:33375982 -3.2.1.58 4-nitrophenyl beta-l-fucoside uncultured bacterium 6.0 6.0 1 PMID:33375982 -3.2.1.58 4-nitrophenyl-alpha-l-arabinofuranoside cellulomonas fimi 123.6 123.6 1 PMID:25797391 -3.2.1.58 cellobiose rhizomucor miehei 0.043 0.043 1 PMID:25577102 -3.2.1.58 cellotetraose rhizomucor miehei 0.059 0.059 1 PMID:25577102 -3.2.1.58 cellotriose rhizomucor miehei 0.067 0.067 1 PMID:25577102 -3.2.1.58 gentobiose rhizomucor miehei 0.056 0.056 1 PMID:25577102 -3.2.1.58 laminaran rasamsonia emersonii 29550.0 29550.0 1 PMID:20882275 -3.2.1.58 laminaran rhizomucor miehei 0.033 0.033 1 PMID:25577102 -3.2.1.58 laminaribiose phanerodontia chrysosporium 45.6 39.45 2 PMID:15582611 -3.2.1.58 laminaribiose rhizomucor miehei 0.078 0.078 1 PMID:25577102 -3.2.1.58 laminaribiose uncultured bacterium 51.7 51.7 1 PMID:33375982 -3.2.1.58 laminarin aplysia kurodai 0.05 0.05 1 PMID:19883786 -3.2.1.58 laminarin candida albicans 157.0 157.0 1 PMID:20875088 -3.2.1.58 laminarin uncultured bacterium 122.4 122.4 1 PMID:33375982 -3.2.1.58 laminaripentaose abracris flavolineata 1.53 1.53 1 PMID:17720633 -3.2.1.58 laminaripentaose phanerodontia chrysosporium 33.7 33.7 1 PMID:15582611 -3.2.1.58 laminaripentaose uncultured bacterium 125.4 125.4 1 PMID:33375982 -3.2.1.58 laminaritetraose abracris flavolineata 2.3 2.3 1 PMID:17720633 -3.2.1.58 laminaritetraose aplysia kurodai 4.79 4.79 1 PMID:19883786 -3.2.1.58 laminaritetraose phanerodontia chrysosporium 39.0 39.0 1 PMID:15582611 -3.2.1.58 laminaritetraose uncultured bacterium 106.9 106.9 1 PMID:33375982 -3.2.1.58 laminaritriose phanerodontia chrysosporium 41.8 41.8 1 PMID:15582611 -3.2.1.58 laminaritriose rhizomucor miehei 0.077 0.077 1 PMID:25577102 -3.2.1.58 laminaritriose uncultured bacterium 61.4 61.4 1 PMID:33375982 -3.2.1.59 alpha-1,3-glucan niallia circulans 91.3 91.3 1 PMID:23470772 -3.2.1.6 1,3-1,4-beta-d-glucan rasamsonia emersonii 281.2 198.0 2 PMID:14599597 -3.2.1.6 barley beta-glucan rasamsonia emersonii 269.0 269.0 1 PMID:11427240 -3.2.1.6 beta-1,3-1,4-glucan bacillus subtilis 7207.0 7207.0 1 PMID:18365147 -3.2.1.6 beta-glucan acetivibrio thermocellus 1233.0 1233.0 1 PMID:18292875 -3.2.1.6 beta-glucan rhizomucor miehei 15600.0 15600.0 1 PMID:17589838 -3.2.1.6 beta-glucan thermothelomyces heterothallicus 156.0 156.0 1 PMID:25869365 -3.2.1.6 carboxymethylcellulose rasamsonia emersonii 632.8 387.7 2 PMID:14599597 -3.2.1.6 glc-beta(1,4)-glc-beta(1,3)-glc-methylumbelliferyl acetivibrio thermocellus 0.383 0.383 1 PMID:18292875 -3.2.1.6 laminarihexaose laceyella putida 582.0 582.0 1 PMID:26392136 -3.2.1.6 laminarin aplysia kurodai 23.1 23.1 1 PMID:19883786 -3.2.1.6 laminarin periplaneta americana 750.0 750.0 1 PMID:14563360 -3.2.1.6 laminarin thermothelomyces heterothallicus 156.0 156.0 1 PMID:25869365 -3.2.1.6 laminaripentaose laceyella putida 355.0 355.0 1 PMID:26392136 -3.2.1.6 laminaritetraose aplysia kurodai 0.21 0.21 1 PMID:19883786 -3.2.1.6 laminaritetraose laceyella putida 188.0 188.0 1 PMID:26392136 -3.2.1.6 lichenan bacillus subtilis 1350.0 1350.0 1 PMID:18365147 -3.2.1.6 lichenan paenibacillus macerans 1191.0 1191.0 1 PMID:16483609 -3.2.1.6 lichenan rasamsonia emersonii 485.0 329.85 2 PMID:11427240;PMID:14599597 -3.2.1.6 lichenin periplaneta americana 1050.0 1050.0 1 PMID:14563360 -3.2.1.60 maltotetraose roseateles saccharophilus 21900.0 21900.0 1 PMID:35563929 -3.2.1.60 soluble starch roseateles saccharophilus 1673.73 1385.7150000000001 2 PMID:32167164 -3.2.1.62 2-chloro-4-nitrophenyl beta-cellobioside rhodococcus sp. m-777 3.7 3.7 1 * -3.2.1.62 4-o-beta-d-galactopyranosyl-d-glucopyranoside ovis aries aries 33.8 33.8 1 PMID:10692580 -3.2.1.62 c6-7-nitro-2,1,3-benzoxadiazole-glucosylceramide cryptococcus neoformans 0.0383 0.0383 1 PMID:22072709 -3.2.1.62 daidzein-7-beta-d-glucopyranoside ovis aries aries 2.1 2.1 1 PMID:10692580 -3.2.1.62 daidzein-7-glucoside ovis aries 2.1 2.1 1 PMID:10692580 -3.2.1.62 genistein-7-beta-d-glucopyranoside ovis aries aries 6.5 6.5 1 PMID:10692580 -3.2.1.62 genistein-7-glucoside ovis aries 6.5 6.5 1 PMID:10692580 -3.2.1.62 lactose ovis aries 33.8 33.8 1 PMID:10692580 -3.2.1.62 phlorizin ovis aries 0.5 0.5 1 PMID:10692580 -3.2.1.62 phlorizin ovis aries aries 0.5 0.5 1 * -3.2.1.62 pyridoxine-5'-beta-d-glucoside rattus norvegicus 1.0 1.0 1 PMID:12023280 -3.2.1.62 quercetin 3-o-beta-d-glucopyranoside ovis aries aries 6.3 6.3 1 PMID:10692580 -3.2.1.62 quercetin-3-glucoside ovis aries 6.3 6.3 1 PMID:10692580 -3.2.1.62 quercetin-4'-glucoside ovis aries 7.5 7.5 1 PMID:10692580 -3.2.1.62 quercetin-4-beta-d-glucopyranoside ovis aries aries 7.5 7.5 1 PMID:10692580 -3.2.1.63 alpha-l-fuc-(1->2)-d-gal clostridium perfringens 15.4 15.4 1 PMID:26663202 -3.2.1.65 high molecular weight levan belliella baltica 98.09 98.09 1 PMID:36826427 -3.2.1.65 high molecular weight levan capnocytophaga ochracea 158.04 158.04 1 PMID:36826427 -3.2.1.65 high molecular weight levan dyadobacter fermentans 99.21 99.21 1 PMID:36826427 -3.2.1.65 high molecular weight levan paenarthrobacter aurescens 312.5 312.5 1 PMID:36826427 -3.2.1.65 high molecular weight levan vibrio natriegens 71.03 71.03 1 PMID:36826427 -3.2.1.65 levan azotobacter chroococcum 6554.0 6554.0 1 PMID:33436213 -3.2.1.65 levan shouchella lehensis g1 25.46 21.24 5 PMID:32380107;PMID:34119133 -3.2.1.65 low molecular weight levan bacillus subtilis 9.3 9.3 1 PMID:26600431 -3.2.1.65 low molecular weight levan belliella baltica 106.61 106.61 1 PMID:36826427 -3.2.1.65 low molecular weight levan capnocytophaga ochracea 193.2 193.2 1 PMID:36826427 -3.2.1.65 low molecular weight levan dyadobacter fermentans 101.1 101.1 1 PMID:36826427 -3.2.1.65 low molecular weight levan paenarthrobacter aurescens 117.62 117.62 1 PMID:36826427 -3.2.1.65 low molecular weight levan vibrio natriegens 75.41 75.41 1 PMID:36826427 -3.2.1.65 sucrose bacillus subtilis 164.6 164.6 1 PMID:26600431 -3.2.1.67 (1,4-alpha-d-galacturonide)2 daucus carota 0.17 0.17 1 PMID:16402551 -3.2.1.67 (1,4-alpha-d-galacturonide)3 daucus carota 0.44 0.44 1 PMID:16402551 -3.2.1.67 (1,4-alpha-d-galacturonide)4 daucus carota 0.52 0.52 1 PMID:16402551 -3.2.1.67 (1,4-alpha-d-galacturonide)5 daucus carota 0.57 0.57 1 PMID:16402551 -3.2.1.67 (1,4-alpha-d-galacturonide)6 daucus carota 0.59 0.59 1 PMID:16402551 -3.2.1.67 (1,4-alpha-d-galacturonide)7 daucus carota 0.33 0.33 1 PMID:16402551 -3.2.1.67 (1,4-alpha-d-galacturonide)8 daucus carota 0.31 0.31 1 PMID:16402551 -3.2.1.67 [(1->4)-alpha-d-galacturonide]170 thermotoga maritima 936.0 936.0 1 PMID:16262687 -3.2.1.67 [(1->4)-alpha-d-galacturonide]2 rhizopus arrhizus 10.3 7.1000000000000005 2 PMID:23813338 -3.2.1.67 [(1->4)-alpha-d-galacturonide]2 thermotoga maritima 182.0 182.0 1 PMID:16262687 -3.2.1.67 [(1->4)-alpha-d-galacturonide]3 rhizopus arrhizus 10.7 10.7 1 PMID:23813338 -3.2.1.67 [(1->4)-alpha-d-galacturonide]3 thermotoga maritima 685.0 685.0 1 PMID:16262687 -3.2.1.67 [(1->4)-alpha-d-galacturonide]4 thermotoga maritima 829.0 829.0 1 PMID:16262687 -3.2.1.67 [(1->4)-alpha-d-galacturonide]5 thermotoga maritima 934.0 934.0 1 PMID:16262687 -3.2.1.67 [(1->4)-alpha-d-galacturonide]6 thermotoga maritima 821.0 821.0 1 PMID:16262687 -3.2.1.67 [(1->4)-alpha-d-galacturonide]7 thermotoga maritima 860.0 860.0 1 PMID:16262687 -3.2.1.67 [(1->4)-alpha-d-galacturonide]8 thermotoga maritima 843.0 843.0 1 PMID:16262687 -3.2.1.67 [(1->4)-alpha-d-galacturonide]n aspergillus niveus 393.3 393.3 1 PMID:23613286 -3.2.1.67 [(1->4)-alpha-d-galacturonide]n penicillium oxalicum 4068.0 3045.0 2 PMID:24584459 -3.2.1.67 [(1->4)-alpha-d-galacturonide]n rhizopus arrhizus 2230.0 2230.0 1 * -3.2.1.67 citric pectin aspergillus giganteus 770.0 770.0 1 PMID:20204453 -3.2.1.67 digalacturonic acid rhodothermus marinus 11.7 11.7 1 PMID:28555295 -3.2.1.67 digalacturonic acid thermotoga thermophilus 14.1 14.1 1 PMID:27209035 -3.2.1.67 polygalacturonic acid aspergillus giganteus 690.0 690.0 1 PMID:20204453 -3.2.1.67 polygalacturonic acid aspergillus niger 194.0 194.0 1 PMID:28567634 -3.2.1.67 polygalacturonic acid bacillus licheniformis 2.58 2.58 1 PMID:28993256 -3.2.1.67 polygalacturonic acid penicillium janthinellum 277.0 277.0 1 PMID:31461202 -3.2.1.67 polygalacturonic acid rhodothermus marinus 6.02 6.02 1 PMID:28555295 -3.2.1.67 polygalacturonic acid saccharobesus litoralis 6.4 6.4 1 PMID:36656114 -3.2.1.67 polygalacturonic acid thermotoga thermophilus 10.6 10.6 1 PMID:27209035 -3.2.1.67 trigalacturonic acid rhodothermus marinus 21.9 21.9 1 PMID:28555295 -3.2.1.67 trigalacturonic acid thermotoga thermophilus 9.55 9.55 1 PMID:27209035 -3.2.1.68 glycogen lederbergia lenta 660.0 660.0 1 PMID:26597030 -3.2.1.68 glycogen rhizopus arrhizus 0.000117 0.000117 1 PMID:31868558 -3.2.1.7 agavin kluyveromyces marxianus 1345.0 842.0 2 PMID:37150366 -3.2.1.7 chicory inulin kluyveromyces marxianus 1636.0 1508.0 2 PMID:37150366 -3.2.1.7 inulin arthrobacter sp. s37 711.7 711.7 1 PMID:18395004 -3.2.1.7 inulin aspergillus ficuum 0.35 0.162 3 PMID:1368526 -3.2.1.7 inulin aspergillus neotritici 2.17e-05 2.17e-05 1 PMID:32890562 -3.2.1.7 inulin aspergillus niger 211.8 106.05550000000001 2 PMID:31126466;PMID:37881510 -3.2.1.7 inulin aspergillus terreus 0.111 0.084 5 PMID:36234954 -3.2.1.7 inulin bacillus smithii 3.33 3.33 1 PMID:18663416 -3.2.1.7 inulin lipomyces starkeyi 2393.2 2393.2 1 PMID:31233793 -3.2.1.7 inulin pseudomonas mucidolens 264.08 158.58 3 PMID:35513090 -3.2.1.7 inulin talaromyces purpureogenus 850.0 485.0 2 PMID:29388362 -3.2.1.7 inulin xanthomonas phaseoli pv. phaseoli 0.0024 0.0024 1 PMID:27904343 -3.2.1.7 raffinose bacillus smithii 0.5 0.5 1 PMID:18663416 -3.2.1.7 sucrose aspergillus ficuum 0.053 0.038 3 PMID:1368526 -3.2.1.7 sucrose aspergillus niger 0.636 0.636 1 PMID:37881510 -3.2.1.7 sucrose bacillus smithii 0.1377 0.1377 1 PMID:18663416 -3.2.1.7 sucrose kluyveromyces marxianus 845.0 629.5 2 PMID:37150366 -3.2.1.70 4-nitrophenyl-alpha-d-glucopyranoside lactobacillus acidophilus 597.0 597.0 1 PMID:22685275 -3.2.1.70 dextran arthrobacter globiformis 95.2 95.2 1 * -3.2.1.70 dextran lactobacillus acidophilus 384.0 384.0 1 PMID:22685275 -3.2.1.70 isomaltoheptaose streptococcus mutans 449.0 449.0 1 PMID:16503208 -3.2.1.70 isomaltohexaose streptococcus mutans 401.0 401.0 1 PMID:16503208 -3.2.1.70 isomaltopentaose streptococcus mutans 419.0 419.0 1 PMID:16503208 -3.2.1.70 isomaltose lactobacillus acidophilus 517.0 517.0 1 PMID:22685275 -3.2.1.70 isomaltose streptococcus mutans 483.0 483.0 1 PMID:16503208 -3.2.1.70 isomaltotetraose lactobacillus acidophilus 501.0 501.0 1 PMID:22685275 -3.2.1.70 isomaltotetraose streptococcus mutans 499.0 499.0 1 PMID:16503208 -3.2.1.70 isomaltotriose lactobacillus acidophilus 475.0 475.0 1 PMID:22685275 -3.2.1.70 isomaltotriose streptococcus mutans 541.0 541.0 1 PMID:16503208 -3.2.1.70 p-nitrophenyl alpha-d-glucoside streptococcus mutans 235.0 235.0 1 PMID:16503208 -3.2.1.70 panose lactobacillus acidophilus 612.0 612.0 1 PMID:22685275 -3.2.1.70 panose streptococcus mutans 538.0 538.0 1 PMID:16503208 -3.2.1.73 1,3-1,4-beta-d-glucan fibrobacter succinogenes 2.25 2.25 1 PMID:21959377 -3.2.1.73 4-methylumbelliferyl cellobiose synechocystis sp. pcc 6803 1.35 1.35 1 PMID:18684392 -3.2.1.73 4-methylumbelliferyl laminaribiose synechocystis sp. pcc 6803 0.327 0.327 1 PMID:18684392 -3.2.1.73 azo blue barley beta-glucan bacillus tequilensis 185.0 161.0 2 PMID:27100881 -3.2.1.73 azo blue beta-glucan bacillus amyloliquefaciens 267.0 188.0 2 PMID:25048240 -3.2.1.73 azo-barley glucan bacillus tequilensis 137.0 137.0 1 PMID:27627900 -3.2.1.73 barley beta-glucan aspergillus fumigatus 159.9 159.9 1 PMID:29715559 -3.2.1.73 barley beta-glucan aspergillus niger 19.11 19.11 1 PMID:23987435 -3.2.1.73 barley beta-glucan bacillus pumilus 5750.0 5750.0 1 PMID:27838418 -3.2.1.73 barley beta-glucan bacillus sp. sj-10 588.54 297.995 2 PMID:27765566;PMID:31112758 -3.2.1.73 barley beta-glucan bacillus subtilis 0.091 0.08249999999999999 2 PMID:18350387 -3.2.1.73 barley beta-glucan bacillus tequilensis 184.9 184.9 1 PMID:27100881 -3.2.1.73 barley beta-glucan chaetomium sp. cq31 386.3 386.3 1 PMID:34329700 -3.2.1.73 barley beta-glucan malbranchea cinnamomea 0.016 0.016 1 PMID:25113013 -3.2.1.73 barley beta-glucan neocallimastix patriciarum 133.3 76.03999999999999 4 PMID:22492445 -3.2.1.73 barley beta-glucan paecilomyces sp. 81.6 81.6 1 PMID:18543932 -3.2.1.73 barley beta-glucan paecilomyces sp. 'thermophila' 102.0 102.0 1 PMID:22370539 -3.2.1.73 barley beta-glucan paenibacillus sp. x4 2067.0 1151.0 2 PMID:28180917 -3.2.1.73 barley beta-glucan synechocystis sp. pcc 6803 8.4 8.4 1 PMID:18684392 -3.2.1.73 barley beta-glucan thermotoga maritima 6.2 6.2 1 * -3.2.1.73 barley glucan bispora sp. mey-1 32970.0 32970.0 1 PMID:35366731 -3.2.1.73 barley glucan evansstolkia leycettana 8500.0 8500.0 1 PMID:35366731 -3.2.1.73 barley glucan rhizopus homothallicus 5700.0 5700.0 1 PMID:35366731 -3.2.1.73 beta-1,3-1,4-glucan laetiporus sulphureus 13.5 13.5 1 PMID:19734720 -3.2.1.73 beta-d-glc-(1-3)-alpha-d-glc-fluoride bacillus licheniformis 0.04 0.04 1 PMID:14609341 -3.2.1.73 beta-d-glc-(1-4)-beta-d-glc-(1-3)-alpha-d-glc-fluoride bacillus licheniformis 0.91 0.91 1 PMID:14609341 -3.2.1.73 beta-d-glc-(1-4)-beta-d-glc-(1-4)-beta-d-glc-(1-3)-alpha-d-glc-fluoride bacillus licheniformis 1.35 1.35 1 PMID:14609341 -3.2.1.73 beta-d-glucan acetivibrio thermocellus 20.3 11.3 2 PMID:21735259 -3.2.1.73 beta-d-glucan bacillus amyloliquefaciens 20.3 14.75 2 PMID:21735259 -3.2.1.73 beta-glucan uncultured bacterium 103.8 103.8 1 PMID:33482202 -3.2.1.73 carboxymethyl cellulose aspergillus fumigatus 43.32 43.32 1 PMID:29715559 -3.2.1.73 carboxymethylcellulose laetiporus sulphureus 5.3 5.3 1 PMID:19734720 -3.2.1.73 laminarin bacillus sp. (in: firmicutes) 0.65 0.095 17 PMID:16483609 -3.2.1.73 laminarin rhizopus homothallicus 30.0 30.0 1 PMID:35366731 -3.2.1.73 lichenan aspergillus niger 13.32 13.32 1 PMID:23987435 -3.2.1.73 lichenan bacillus licheniformis 708.3 384.15 2 * -3.2.1.73 lichenan bacillus pumilus 2613.0 2613.0 1 PMID:27838418 -3.2.1.73 lichenan bacillus sp. (in: firmicutes) 1191.0 276.0 19 PMID:16483609 -3.2.1.73 lichenan bacillus subtilis 1220.0 1220.0 1 PMID:23012443 -3.2.1.73 lichenan fibrobacter succinogenes 3920.0 3417.5 4 PMID:19018102;PMID:19714803;PMID:20635417;PMID:21959377 -3.2.1.73 lichenan malbranchea cinnamomea 0.007 0.007 1 PMID:25113013 -3.2.1.73 lichenan paecilomyces sp. 166.4 166.4 1 PMID:18543932 -3.2.1.73 lichenan paenibacillus macerans 1020.0 1020.0 1 PMID:7852389 -3.2.1.73 lichenan penicillium occitanis (nom. inval.) 1.707 1.707 1 * -3.2.1.73 lichenan synechocystis sp. pcc 6803 3.71 3.71 1 PMID:18684392 -3.2.1.73 lichenan thermotoga maritima 7.0 7.0 1 * -3.2.1.73 lichenan uncultured bacterium 66.0 66.0 1 PMID:33482202 -3.2.1.73 lichenin bispora sp. mey-1 18700.0 18700.0 1 PMID:35366731 -3.2.1.73 lichenin chaetomium sp. cq31 452.7 452.7 1 PMID:34329700 -3.2.1.73 lichenin evansstolkia leycettana 3000.0 3000.0 1 PMID:35366731 -3.2.1.73 lichenin rhizopus homothallicus 6050.0 6050.0 1 PMID:35366731 -3.2.1.73 oat beta-glucan chaetomium sp. cq31 401.3 401.3 1 PMID:34329700 -3.2.1.73 oat beta-glucan malbranchea cinnamomea 0.022 0.022 1 PMID:25113013 -3.2.1.73 xyloglucan uncultured bacterium 58.3 58.3 1 PMID:33482202 -3.2.1.74 2,4-dinitrophenol cellobiose thermobifida fusca 0.00039 0.00039 1 PMID:10931180 -3.2.1.74 4-nitrophenyl alpha-d-glucoside cytophaga hutchinsonii 0.41 0.41 1 PMID:32577801 -3.2.1.74 4-nitrophenyl beta-d-cellobioside uncultured bacterium 69.6 69.6 1 * -3.2.1.74 4-nitrophenyl beta-d-glucopyranoside stereum hirsutum 4945.0 4945.0 1 PMID:20532763 -3.2.1.74 4-nitrophenyl beta-d-glucopyranoside uncultured rumen bacterium 203.0 164.8 2 PMID:22020745 -3.2.1.74 barley beta-glucan paenibacillus curdlanolyticus 8.0 8.0 1 PMID:27871388 -3.2.1.74 cellobiose cytophaga hutchinsonii 17.97 17.97 1 PMID:32577801 -3.2.1.74 cellobiose fibrobacter succinogenes subsp. succinogenes s85 0.25 0.25 1 PMID:18203823 -3.2.1.74 cellobiose stereum hirsutum 281.0 281.0 1 PMID:20532763 -3.2.1.74 cellobiose trichoderma reesei 32.0 32.0 1 PMID:18587885 -3.2.1.74 cellohexaose fibrobacter succinogenes subsp. succinogenes s85 16.3 16.3 1 PMID:18203823 -3.2.1.74 cellohexose cytophaga hutchinsonii 105.2 105.2 1 PMID:32577801 -3.2.1.74 cellopentaose fibrobacter succinogenes subsp. succinogenes s85 16.4 16.4 1 PMID:18203823 -3.2.1.74 cellopentose cytophaga hutchinsonii 141.0 141.0 1 PMID:32577801 -3.2.1.74 cellotetraose cytophaga hutchinsonii 133.7 133.7 1 PMID:32577801 -3.2.1.74 cellotetraose fibrobacter succinogenes subsp. succinogenes s85 18.6 18.6 1 PMID:18203823 -3.2.1.74 cellotriose cytophaga hutchinsonii 174.7 174.7 1 PMID:32577801 -3.2.1.74 cellotriose fibrobacter succinogenes subsp. succinogenes s85 6.21 6.21 1 PMID:18203823 -3.2.1.75 laminarin saccharophagus degradans 28.9 28.9 1 PMID:27521023 -3.2.1.75 pustulan saccharophagus degradans 135.6 135.6 1 PMID:27521023 -3.2.1.75 pustulan trichoderma harzianum 30.0 30.0 1 PMID:33309029 -3.2.1.76 4-methylumbelliferyl alpha-l-iduronide homo sapiens 11.8 10.600000000000001 2 PMID:30058762 -3.2.1.76 5-fluoro-alpha-l-idopyranosyluronic acid fluoride homo sapiens 0.83 0.83 1 PMID:12834357 -3.2.1.78 1,4-beta-d-mannan aspergillus niger 148.0 148.0 1 PMID:19912637 -3.2.1.78 4-methylumbelliferyl mannotrioside trichoderma reesei 0.03 0.03 1 * -3.2.1.78 beta-1,4-d-mannan bacillus licheniformis 18200.0 18200.0 1 PMID:20380743 -3.2.1.78 carob galactomannan aspergillus niger 292.0 292.0 1 PMID:19912637 -3.2.1.78 carob galactomannan bacillus sp. kw1 275.2 275.2 1 PMID:33144255 -3.2.1.78 galactomannan hordeum vulgare 12.9 12.9 1 PMID:16771710 -3.2.1.78 galactomannan streptomyces sp. nrrl b-24484 120.0 120.0 1 PMID:29153955 -3.2.1.78 glucomannan aspergillus niger 215.0 215.0 1 PMID:19912637 -3.2.1.78 glucomannan bacillus licheniformis 21000.0 21000.0 1 PMID:20380743 -3.2.1.78 glucomannan streptomyces sp. nrrl b-24484 340.0 340.0 1 PMID:29153955 -3.2.1.78 guar gum aspergillus oryzae 290.0 290.0 1 PMID:28105485 -3.2.1.78 guar gum hypothenemus hampei 50.87 50.87 1 PMID:23965285 -3.2.1.78 guar gum rhizomucor miehei 4.77 4.77 1 PMID:23252695 -3.2.1.78 guar gum shouchella clausii 109.9 109.9 1 PMID:30098601 -3.2.1.78 konjac flour aspergillus oryzae 620.0 620.0 1 PMID:28105485 -3.2.1.78 konjac glucomannan shouchella clausii 1238.9 1238.9 1 PMID:30098601 -3.2.1.78 locust bean gum aspergillus oryzae 580.0 580.0 1 PMID:28105485 -3.2.1.78 locust bean gum bacillus licheniformis 31200.0 31200.0 1 PMID:20380743 -3.2.1.78 locust bean gum glycine max 25.2 25.2 1 PMID:21425861 -3.2.1.78 locust bean gum rhizomucor miehei 14.9 14.9 1 PMID:23252695 -3.2.1.78 locust bean gum shouchella clausii 1376.1 1376.1 1 PMID:30098601 -3.2.1.78 locust bean gum trichoderma reesei 240.0 240.0 1 * -3.2.1.78 locust bean gum galactomannan aspergillus niger 330.0 330.0 1 PMID:19912637 -3.2.1.78 low viscosity locust bean galactomannan aspergillus fumigatus 2246.0 2090.5 2 PMID:15541293 -3.2.1.78 low-viscosity locust bean galactomannan bifidobacterium animalis subsp. lactis 1828.0 1828.0 1 PMID:26558435 -3.2.1.78 man-beta-1,4-man-beta-1,4-man-beta-1,4-man aspergillus nidulans 112.0 89.5 2 PMID:21867780 -3.2.1.78 man-beta-1,4-man-beta-1,4-man-beta-1,4-man-beta-1,4-man aspergillus nidulans 193.0 163.5 2 PMID:21867780 -3.2.1.78 manbeta(1-4)manbeta(1-4)man cellulomonas fimi 1.17 1.17 1 PMID:16171384 -3.2.1.78 manbeta(1-4)manbeta(1-4)manbeta(1-4)man cellulomonas fimi 11.64 6.025 2 PMID:16171384 -3.2.1.78 manbeta(1-4)manbeta(1-4)manbeta(1-4)man mytilus edulis 0.7 0.7 1 PMID:16487541 -3.2.1.78 manbeta(1-4)manbeta(1-4)manbeta(1-4)manbeta(1-4)man cellulomonas fimi 52.42 26.34 2 PMID:16171384 -3.2.1.78 manbeta(1-4)manbeta(1-4)manbeta(1-4)manbeta(1-4)man hordeum vulgare 3.9 3.9 1 PMID:16771710 -3.2.1.78 manbeta(1-4)manbeta(1-4)manbeta(1-4)manbeta(1-4)man mytilus edulis 45.0 45.0 1 PMID:16487541 -3.2.1.78 manbeta(1-4)manbeta(1-4)manbeta(1-4)manbeta(1-4)manbeta(1-4)man cellulomonas fimi 77.0 77.0 1 PMID:16171384 -3.2.1.78 manbeta(1-4)manbeta(1-4)manbeta(1-4)manbeta(1-4)manbeta(1-4)man mytilus edulis 99.0 99.0 1 PMID:16487541 -3.2.1.78 mannohexaose klebsiella oxytoca 45.33 45.33 1 PMID:34726170 -3.2.1.78 mannohexaose trichoderma reesei 20.0 20.0 1 * -3.2.1.78 mannopentaose bifidobacterium animalis subsp. lactis 97.0 97.0 1 PMID:26558435 -3.2.1.78 mannopentaose klebsiella oxytoca 18.33 18.33 1 PMID:34726170 -3.2.1.78 mannopentaose trichoderma reesei 13.0 13.0 1 * -3.2.1.78 mannotetraose trichoderma reesei 6.0 6.0 1 * -3.2.1.78 sesbania gum shouchella clausii 164.7 164.7 1 PMID:30098601 -3.2.1.78 tara gum aspergillus oryzae 520.0 520.0 1 PMID:28105485 -3.2.1.8 1,4-beta-d-xylan bacillus subtilis 82.0 70.0 4 PMID:22006920 -3.2.1.8 2,5-dinitrophenyl-beta-d-xylobioside niallia circulans 34.0 34.0 1 PMID:20163191 -3.2.1.8 2-chloro-4-nitrophenyl beta-d-xylobioside thermothelomyces heterothallicus 0.13 0.13 1 PMID:12932372 -3.2.1.8 2-nitrophenyl xylopyranoside rasamsonia emersonii 523.0 434.0 2 * -3.2.1.8 4-methylumbelliferyl-beta-xylobiose thermothelomyces heterothallicus 0.06 0.06 1 PMID:12932372 -3.2.1.8 4-methylumbelliferyl-beta-xylotriose thermothelomyces heterothallicus 66.58 66.58 1 PMID:12932372 -3.2.1.8 4-methylumbelliferyl-xylobiose thermoascus aurantiacus 3333.0 3333.0 1 * -3.2.1.8 4-methylumbelliferyl-xylotriose thermoascus aurantiacus 833.0 833.0 1 * -3.2.1.8 4-nitrophenyl alpha-l-arabinofuranoside acetivibrio thermocellus 104.0 104.0 1 PMID:29224629 -3.2.1.8 4-nitrophenyl alpha-l-arabinofuranoside thermoascus aurantiacus 85.5 85.5 1 * -3.2.1.8 4-nitrophenyl alpha-l-arabinopyranoside thermoascus aurantiacus 133.3 133.3 1 * -3.2.1.8 4-nitrophenyl beta-d-cellobioside duganella sp. pamc 27433 454.86 454.86 1 PMID:33946575 -3.2.1.8 4-nitrophenyl beta-d-cellobioside thermoascus aurantiacus 5000.0 5000.0 1 * -3.2.1.8 4-nitrophenyl beta-d-xylopyranoside thermoascus aurantiacus 769.0 769.0 1 * -3.2.1.8 4-nitrophenyl xylopyranoside rasamsonia emersonii 898.0 479.5 2 * -3.2.1.8 4-o-methyl-d-glucurono-d-xylan fusarium oxysporum f. sp. vasinfectum 0.27 0.27 1 PMID:27602054 -3.2.1.8 arabinoxylan bacillus licheniformis 0.89 0.89 1 PMID:30706219 -3.2.1.8 arabinoxylan penicillium griseofulvum 1166.0 1166.0 1 PMID:19118652 -3.2.1.8 arabinoxylan remersonia thermophila 1785.0 1785.0 1 PMID:24258792 -3.2.1.8 beechwood glucuronoxylan talaromyces pinophilus 96.0 96.0 1 PMID:31492671 -3.2.1.8 beechwood xylan acetivibrio thermocellus 2008.3 2008.3 1 * -3.2.1.8 beechwood xylan aspergillus fumigatus 6483.7 6483.7 1 PMID:31799141 -3.2.1.8 beechwood xylan aspergillus niger 10200.0 10200.0 1 PMID:23670313 -3.2.1.8 beechwood xylan bacillus licheniformis 1.8 1.8 1 PMID:30706219 -3.2.1.8 beechwood xylan bacillus subtilis 268.0 252.5 2 PMID:26923808 -3.2.1.8 beechwood xylan duganella sp. pamc 27433 357.63 357.63 1 PMID:33946575 -3.2.1.8 beechwood xylan luteimicrobium xylanilyticum 248.0 248.0 1 PMID:28813686 -3.2.1.8 beechwood xylan malbranchea cinnamomea 4.18 4.18 1 PMID:25058752 -3.2.1.8 beechwood xylan massilia sp. rbm26 47.3 47.3 1 PMID:26387816 -3.2.1.8 beechwood xylan melanocarpus albomyces 83.8 47.25 2 PMID:10923787 -3.2.1.8 beechwood xylan pseudopedobacter saltans 52.2 52.2 1 * -3.2.1.8 beechwood xylan pseudothermotoga thermarum 520.0 520.0 1 PMID:24170174 -3.2.1.8 beechwood xylan remersonia thermophila 1034.0 1034.0 1 PMID:24258792 -3.2.1.8 beechwood xylan rhizophlyctis rosea 106.25 80.525 2 PMID:30397764 -3.2.1.8 beechwood xylan rhodothermaceae bacterium ra 33.72 33.72 1 PMID:31376486 -3.2.1.8 beechwood xylan thermoanaerobacterium saccharolyticum 34015.3 34015.3 1 PMID:37833340 -3.2.1.8 beechwood xylan thermomyces lanuginosus 3430.0 3430.0 1 PMID:23793944 -3.2.1.8 beechwood xylan thermothielavioides terrestris 479.0 479.0 1 PMID:27900528 -3.2.1.8 beechwood xylan thermotoga maritima 4204.0 4204.0 1 PMID:32732029 -3.2.1.8 beechwood xylan uncultured bacterium 2323.0 1189.15 2 PMID:26790627;PMID:34001974 -3.2.1.8 beechwood xylan unidentified microorganism 1210.0 1210.0 1 PMID:28774672 -3.2.1.8 beta-1,4-d-glucan thermochaetoides thermophila 0.0007 0.0007 1 PMID:29842954 -3.2.1.8 beta-1,4-d-xylan thermochaetoides thermophila 0.00158 0.00158 2 PMID:29842954 -3.2.1.8 beta-1,4-xylan acidomyces acidophilus 68.2 68.2 1 PMID:19640703 -3.2.1.8 beta-1,4-xylan aspergillus sulphureus 6551.0 6551.0 1 PMID:19412581 -3.2.1.8 beta-1,4-xylan kocuria sp. mn22 185.1 185.1 1 PMID:19809242 -3.2.1.8 beta-1,4-xylan nesterenkonia xinjiangensis 18.12 12.245000000000001 2 PMID:19838860 -3.2.1.8 beta-1,4-xylan penicillium sp. cgmcc 1669 5416.0 5416.0 1 PMID:19626289 -3.2.1.8 beta-1,4-xylan pseudozyma hubeiensis 3333.0 2358.0 2 PMID:19692229 -3.2.1.8 beta-1,4-xylan sphingobacterium sp. tn19 603.8 603.8 1 PMID:19554324 -3.2.1.8 beta-1,4-xylan trichoderma reesei 512.4 199.7 9 PMID:19527524;PMID:19556747;PMID:20064285 -3.2.1.8 birchwood xylan aspergillus fumigatus 1341.0 1341.0 1 PMID:31799141 -3.2.1.8 birchwood xylan aspergillus niger 7764.0 140.1 3 PMID:17445930;PMID:23670313 -3.2.1.8 birchwood xylan bacillus licheniformis 1.7 1.7 1 PMID:30706219 -3.2.1.8 birchwood xylan bacillus subtilis 140.1 70.06949999999999 2 PMID:17445930 -3.2.1.8 birchwood xylan duganella sp. pamc 27433 127.12 127.12 1 PMID:33946575 -3.2.1.8 birchwood xylan halalkalibacterium halodurans 23.1 23.1 1 PMID:31079316 -3.2.1.8 birchwood xylan hordeum vulgare 72.07 37.035 2 PMID:17383610 -3.2.1.8 birchwood xylan luteimicrobium xylanilyticum 222.0 222.0 1 PMID:28813686 -3.2.1.8 birchwood xylan malbranchea cinnamomea 4.26 4.26 1 PMID:25058752 -3.2.1.8 birchwood xylan melanocarpus albomyces 73.0 41.75 2 PMID:10923787 -3.2.1.8 birchwood xylan penicillium citrinum 245.0 245.0 1 PMID:30923012 -3.2.1.8 birchwood xylan penicillium griseofulvum 292.0 284.5 2 PMID:17216454 -3.2.1.8 birchwood xylan pseudopedobacter saltans 36.8 36.8 1 * -3.2.1.8 birchwood xylan streptomyces fradiae 103.4 103.4 1 PMID:18388456 -3.2.1.8 birchwood xylan streptomyces sp. s27 1737.0 1737.0 1 PMID:19002659 -3.2.1.8 birchwood xylan talaromyces funiculosus 997.0 934.5 2 PMID:17216454 -3.2.1.8 birchwood xylan thermothielavioides terrestris 465.0 465.0 1 PMID:27900528 -3.2.1.8 birchwood xylan uncultured bacterium 125.9 125.9 1 PMID:26358761 -3.2.1.8 carboxymethyl cellulose thermochaetoides thermophila 0.00211 0.00211 1 PMID:29842954 -3.2.1.8 carboxymethyl cellulose thermothielavioides terrestris 263.0 263.0 1 PMID:27900528 -3.2.1.8 carboxymethylcellulose albifimbria verrucaria 3.0 3.0 1 * -3.2.1.8 glucuronoxylan bacillus licheniformis 1.03 1.03 1 PMID:30706219 -3.2.1.8 insoluble oat spelt xylan remersonia thermophila 1657.0 1657.0 1 PMID:24258792 -3.2.1.8 larchwood xylan melanocarpus albomyces 53.4 41.2 3 PMID:10923787 -3.2.1.8 oat spelt xylan aspergillus niger 17250.0 17250.0 1 PMID:23670313 -3.2.1.8 oat spelt xylan duganella sp. pamc 27433 38.85 38.85 1 PMID:33946575 -3.2.1.8 oat spelt xylan hordeum vulgare 47.01 23.512999999999998 2 PMID:17383610 -3.2.1.8 oat spelt xylan luteimicrobium xylanilyticum 390.0 390.0 1 PMID:28813686 -3.2.1.8 oat spelt xylan malbranchea cinnamomea 4.58 4.58 1 PMID:25058752 -3.2.1.8 oat spelt xylan streptomyces fradiae 170.8 170.8 1 PMID:18388456 -3.2.1.8 oat spelt xylan streptomyces sp. s27 3475.0 3475.0 1 PMID:19002659 -3.2.1.8 oat spelt xylan thermomyces lanuginosus 5967.0 4283.5 2 PMID:23793944 -3.2.1.8 oat spelt xylan thermothielavioides terrestris 550.0 550.0 1 PMID:27900528 -3.2.1.8 oat-spelt xylan streptomyces sp. tn119 49.2 49.2 1 PMID:19412576 -3.2.1.8 oat-spelt xylan uncultured bacterium 2.583 2.583 1 PMID:18515360 -3.2.1.8 p-nitrophenyl-beta-d-xylobioside streptomyces olivaceoviridis 42.17 21.111150000000002 2 PMID:19279191 -3.2.1.8 soluble birchwood xylan paenibacillus curdlanolyticus 129.0 129.0 1 PMID:27871388 -3.2.1.8 soluble oat spelt xylan remersonia thermophila 1492.0 1492.0 1 PMID:24258792 -3.2.1.8 wheat arabinoxylan duganella sp. pamc 27433 43.54 43.54 1 PMID:33946575 -3.2.1.8 wheat arabinoxylan luteimicrobium xylanilyticum 85.0 85.0 1 PMID:28813686 -3.2.1.8 wheat arabinoxylan penicillium griseofulvum 545.0 545.0 1 PMID:18384043 -3.2.1.8 wheat arabinoxylan talaromyces pinophilus 162.0 162.0 1 PMID:31492671 -3.2.1.8 xylan acrophialophora nainiana 0.099 0.07150000000000001 4 PMID:12829303 -3.2.1.8 xylan albifimbria verrucaria 28.7 27.35 2 * -3.2.1.8 xylan aspergillus giganteus 1345.0 749.5 4 PMID:15114860 -3.2.1.8 xylan aspergillus terreus 1587.28 1587.28 1 PMID:29684454 -3.2.1.8 xylan pseudoalteromonas haloplanktis 1247.0 1247.0 1 PMID:12089151 -3.2.1.8 xylan pseudopedobacter saltans 45.9 45.9 1 * -3.2.1.8 xylan talaromyces funiculosus 5405.0 5405.0 1 PMID:15450181 -3.2.1.8 xylan thermobifida fusca 86.0 86.0 1 PMID:18292971 -3.2.1.8 xylan thermomonospora sp. 223.3 223.3 1 PMID:11263969 -3.2.1.8 xylan thermotoga maritima 106.5 98.1 2 * -3.2.1.8 xylohexaose trichoderma reesei 68.0 68.0 1 PMID:17475200 -3.2.1.8 xylopentaose trichoderma reesei 50.3 50.3 1 PMID:17475200 -3.2.1.8 xylotetraose trichoderma reesei 0.162 0.162 1 PMID:17475200 -3.2.1.8 xylotriose trichoderma reesei 0.045 0.045 1 PMID:17475200 -3.2.1.80 1-kestose arabidopsis thaliana 21.0 21.0 1 PMID:17873089 -3.2.1.80 actilight kluyveromyces marxianus 1.09 1.09 1 PMID:21067917 -3.2.1.80 agave tequilana fructan kluyveromyces marxianus 0.9 0.9 1 PMID:21067917 -3.2.1.80 agavin kluyveromyces marxianus 339.0 339.0 1 PMID:32777449 -3.2.1.80 inulin kluyveromyces marxianus 1380.0 690.05 2 PMID:21067917;PMID:32777449 -3.2.1.80 inulin penicillium sp. 1110.0 805.0 2 PMID:17502268 -3.2.1.80 levan kluyveromyces marxianus 0.33 0.33 1 PMID:21067917 -3.2.1.80 sucrose kluyveromyces marxianus 414.4 207.83499999999998 2 PMID:21067917;PMID:32777449 -3.2.1.80 sucrose penicillium sp. 5000.0 4165.0 2 PMID:17502268 -3.2.1.81 agarose agarivorans albus 41.0 41.0 1 PMID:19349750 -3.2.1.81 agarose catenovulum agarivorans 2400.0 2400.0 1 PMID:28986239 -3.2.1.81 agarose cellvibrio sp. ky-gh-1 576.3 576.3 1 PMID:37145239 -3.2.1.81 agarose saccharophagus degradans 22.0 22.0 1 PMID:19802606 -3.2.1.81 agarose wenyingzhuangia aestuarii 176.74 176.74 1 PMID:32578425 -3.2.1.81 neoagarodecaose pseudoalteromonas sp. cy24 0.19 0.19 1 PMID:17166842 -3.2.1.81 neoagarododecaose pseudoalteromonas sp. cy24 4.77 4.77 1 PMID:17166842 -3.2.1.81 neoagarotetradecaose pseudoalteromonas sp. cy24 5.16 5.16 1 PMID:17166842 -3.2.1.82 pectin aspergillus niger 160.2 132.7 5 PMID:18500582 -3.2.1.82 polygalacturonic acid aspergillus niger 85.4 85.4 1 PMID:18500582 -3.2.1.83 furcellaran wenyingzhuangia fucanilytica 270.75 270.75 1 PMID:34421852 -3.2.1.83 kappa-carrageen pseudoalteromonas carrageenovora 135.84 135.84 1 PMID:29030427 -3.2.1.83 kappa-carrageen wenyingzhuangia aestuarii 27.54 27.54 1 PMID:29355636 -3.2.1.83 kappa-carrageen zobellia galactanivorans 914.65 914.65 1 PMID:29030427 -3.2.1.83 kappa-carrageenan pseudoalteromonas carrageenovora 806.7 497.65000000000003 2 PMID:34847438 -3.2.1.83 kappa-carrageenan pseudoalteromonas tetraodonis 4.09 4.09 1 * -3.2.1.85 2-nitrophenyl-beta-d-galactopyranoside bacillus amyloliquefaciens 134.45 124.45 3 PMID:33144261 -3.2.1.85 2-nitrophenyl-beta-d-galactopyranoside 6-phosphate lactobacillus gasseri 361.0 283.5 2 PMID:22449746 -3.2.1.85 lactose bacillus amyloliquefaciens 198.24 171.74 3 PMID:33144261 -3.2.1.85 o-nitrophenyl-beta-d-galactopyranoside 6-phosphate lacticaseibacillus casei 57.0 57.0 1 PMID:8309940 -3.2.1.85 o-nitrophenyl-beta-d-galactopyranoside 6-phosphate lactococcus lactis 83.0 83.0 1 PMID:8309940 -3.2.1.85 o-nitrophenyl-beta-d-galactopyranoside 6-phosphate staphylococcus aureus 63.0 63.0 1 PMID:8309940 -3.2.1.85 o-nitrophenyl-beta-d-glucopyranoside 6-phosphate lacticaseibacillus casei 4.0 4.0 1 PMID:8309940 -3.2.1.85 o-nitrophenyl-beta-d-glucopyranoside 6-phosphate lactococcus lactis 7.0 7.0 1 PMID:8309940 -3.2.1.85 o-nitrophenyl-beta-d-glucopyranoside 6-phosphate staphylococcus aureus 9.0 9.0 1 PMID:8309940 -3.2.1.85 p-nitrophenyl-6-phospho-beta-d-galactopyranose lactococcus lactis 22.0 22.0 1 PMID:18615662 -3.2.1.85 p-nitrophenyl-6-phospho-beta-d-glucopyranose lactococcus lactis 5.0 5.0 1 PMID:18615662 -3.2.1.85 p-nitrophenyl-beta-d-galactopyranoside 6-phosphate lacticaseibacillus casei 7.0 7.0 1 PMID:8309940 -3.2.1.85 p-nitrophenyl-beta-d-galactopyranoside 6-phosphate lactococcus lactis 22.0 22.0 1 PMID:8309940 -3.2.1.85 p-nitrophenyl-beta-d-galactopyranoside 6-phosphate staphylococcus aureus 18.0 18.0 1 PMID:8309940 -3.2.1.85 p-nitrophenyl-beta-d-glucopyranoside 6-phosphate lacticaseibacillus casei 2.0 2.0 1 PMID:8309940 -3.2.1.85 p-nitrophenyl-beta-d-glucopyranoside 6-phosphate lactococcus lactis 5.0 5.0 1 PMID:8309940 -3.2.1.85 p-nitrophenyl-beta-d-glucopyranoside 6-phosphate staphylococcus aureus 4.0 4.0 1 PMID:8309940 -3.2.1.86 2,4-dinitrophenyl 6-phospho-beta-d-glucoside thermotoga maritima 2.29 2.29 1 PMID:16401086 -3.2.1.86 2,5-dinitrophenyl 6-phospho-beta-d-glucoside thermotoga maritima 1.95 1.95 1 PMID:16401086 -3.2.1.86 2-nitrophenyl 6-phospho-beta-d-glucoside thermotoga maritima 1.21 1.21 1 PMID:16401086 -3.2.1.86 2-nitrophenyl-beta-d-glucopyranoside 6-phosphate lactobacillus gasseri 41.0 24.5 2 PMID:22449746 -3.2.1.86 3,4-dinitrophenyl 6-phospho-beta-d-glucoside thermotoga maritima 1.15 1.15 1 PMID:16401086 -3.2.1.86 3,5-dichlorophenyl 6-phospho-beta-d-glucoside thermotoga maritima 2.33 2.33 1 PMID:16401086 -3.2.1.86 3-nitrophenyl 6-phospho-beta-d-glucoside thermotoga maritima 4.69 4.69 1 PMID:16401086 -3.2.1.86 4-chloro-2-nitrophenyl 6-phospho-beta-d-glucoside thermotoga maritima 1.69 1.69 1 PMID:16401086 -3.2.1.86 4-cyanophenyl 6-phospho-beta-d-glucoside thermotoga maritima 1.01 0.9 2 PMID:16401086 -3.2.1.86 4-nitrophenyl 6-phospho-beta-d-glucoside thermotoga maritima 0.99 0.99 1 PMID:16401086 -3.2.1.86 4-nitrophenyl 6-phospho-beta-glucoside streptococcus pyogenes 0.24 0.24 1 PMID:26790390 -3.2.1.86 4-nitrophenyl-beta-d-glucopyranoside 6-phosphate streptococcus pneumoniae 195.0 195.0 1 PMID:23580646 -3.2.1.86 4-nitrophenyl-beta-d-glucopyranoside 6-phosphate streptococcus pyogenes 0.243 0.243 1 PMID:23275159 -3.2.1.86 4-tert-butylphenyl 6-phospho-beta-d-glucoside thermotoga maritima 1.21 1.21 1 PMID:16401086 -3.2.1.86 cellobiose 6-phosphate streptococcus pneumoniae 170.0 170.0 1 PMID:23580646 -3.2.1.86 p-nitrophenyl 6-phospho-beta-d-thioglucoside thermotoga maritima 1.6 1.6 1 PMID:15670594 -3.2.1.86 p-nitrophenyl-beta-d-glucopyranoside 6-phosphate thermotoga maritima 1.9 1.9 2 PMID:15237973;PMID:15670594 -3.2.1.88 4-nitrophenyl beta-l-arabinopyranoside caldanaerobius polysaccharolyticus 11.8 11.8 1 PMID:28710263 -3.2.1.89 lupin galactan ignisphaera aggregans 34.0 34.0 1 PMID:34530892 -3.2.1.89 potato galactan bacillus licheniformis 555.8 555.8 1 PMID:26879978 -3.2.1.89 potato galactan bacillus subtilis subsp. subtilis 4667.0 3064.0 2 PMID:36280173 -3.2.1.91 2,4-dinitrophenyl cellobiose thermobifida fusca 0.057 0.057 1 PMID:19523117 -3.2.1.91 2-chloro-4-nitrophenyl-beta-d-cellotrioside rasamsonia emersonii 8.9 8.9 1 PMID:12007616 -3.2.1.91 2-chloronitrophenyl-beta-d-lactoside acetivibrio thermocellus 9108.0 9108.0 1 * -3.2.1.91 4-nitrophenyl beta-d-cellobioside cellulomonas fimi 15.8 15.8 1 PMID:16258187 -3.2.1.91 4-nitrophenyl lactoside trichoderma reesei 0.093 0.093 1 PMID:14568538 -3.2.1.91 4-nitrophenyl-beta-d-cellobioside acetivibrio thermocellus 2952.0 2952.0 1 * -3.2.1.91 alpha-cellobiosyl fluoride mycothermus thermophilus 0.01 0.01 1 * -3.2.1.91 alpha-cellobiosyl fluoride trichoderma reesei 0.54 0.54 1 * -3.2.1.91 beta-cellobiosyl fluoride mycothermus thermophilus 0.071 0.071 1 * -3.2.1.91 beta-cellobiosyl fluoride trichoderma reesei 4.0 4.0 1 * -3.2.1.91 beta-d-glucan thermochaetoides thermophila 0.00054 0.00054 1 PMID:29775713 -3.2.1.91 cellohexaose trichoderma reesei 14.0 14.0 1 PMID:12188666 -3.2.1.91 cellopentaose trichoderma reesei 1.1 1.1 1 PMID:12188666 -3.2.1.91 cellotetraose streptomyces coelicolor 13.3 13.3 2 PMID:29400405 -3.2.1.91 cellotetraose trichoderma reesei 4.1 2.3 2 PMID:12188666;PMID:14568538 -3.2.1.91 cellotriose trichoderma reesei 0.06 0.06 1 PMID:12188666 -3.2.1.91 cellulose thermothelomyces thermophilus 2492.0 2492.0 1 PMID:34735642 -3.2.1.92 4-nitrophenyl-n-acetylmuramic acid bacillus subtilis 1.08 1.08 1 PMID:33684445 -3.2.1.92 murnac-n-acetylglucosamine bacillus subtilis 66.25 66.25 1 PMID:33684445 -3.2.1.93 4-nitrophenyl alpha-d-glucopyranoside bacillus licheniformis 30.3 30.3 1 PMID:26894535 -3.2.1.93 4-nitrophenyl alpha-d-glucopyranoside uncultured bacterium 10.04 10.04 1 PMID:32733411 -3.2.1.93 4-nitrophenyl-alpha-d-glucopyranoside uncultured bacterium 10.71 10.71 1 PMID:32733411 -3.2.1.93 alpha,alpha-trehalose 6-phosphate bacillus licheniformis 46.7 46.7 1 PMID:26894535 -3.2.1.94 4-nitrophenyl alpha-isomaltoside arthrobacter globiformis 23.6 23.6 1 PMID:26330557 -3.2.1.94 dextran arthrobacter dextranolyticus 496.0 496.0 1 PMID:15248038 -3.2.1.94 dextran t2000 arthrobacter globiformis 51.6 51.6 1 PMID:26330557 -3.2.1.96 9-fluorenylmethyloxycarbonyl-labeled asparagine-linked agalactobiantennary oligosaccharide ogataea minuta 5.91 5.91 1 PMID:23436287 -3.2.1.96 dansyl-asn-(glcnac)2(man)5 glutamicibacter protophormiae 365.0 365.0 1 PMID:17567654 -3.2.1.96 sialylglycopeptide rhizomucor pusillus 311.1 311.1 1 PMID:35961816 -3.2.1.97 4,6-dimethoxy-1,3,5-triazin-2-yl alpha-n-acetylgalactosaminide bifidobacterium bifidum 16.7 16.7 1 PMID:22090027 -3.2.1.97 asialo kappa-casein derived glycomacropeptide bifidobacterium longum subsp. longum 207.0 207.0 1 PMID:31176190 -3.2.1.97 asialo-casein glycomacropeptide bifidobacterium longum 194.0 194.0 1 PMID:34694774 -3.2.1.97 asialo-casein glycomacropeptide bifidobacterium longum subsp. longum 194.0 194.0 1 PMID:34694774 -3.2.1.97 galbeta(1,3)galnacalpha-1-p-nitrophenol bifidobacterium longum 37.0 27.4 2 PMID:16141207;PMID:16233817 -3.2.1.97 galbeta(1-3)galnacalpha1-p-nitrophenol bifidobacterium longum 17.8 17.8 1 PMID:16141207 -3.2.1.97 galbeta(1->3)galnacalpha1-4-nitrophenol bifidobacterium longum 166.7 148.7 4 PMID:34694774 -3.2.1.97 galbeta(1->3)galnacalpha1-4-nitrophenol bifidobacterium longum subsp. longum 166.7 148.7 4 PMID:34694774 -3.2.1.97 galbeta1-3galnacalpha-pnp enterococcus faecalis 49.9 49.9 1 PMID:18725192 -3.2.1.97 galbeta1-3galnacalpha1-pnp clostridium perfringens 110.0 110.0 1 PMID:18559962 -3.2.1.97 kappa-casein derived glycomacropeptide bifidobacterium longum subsp. longum 207.0 207.0 1 PMID:31176190 -3.2.1.97 neu5acalpha2-3galbeta1-3galnac o-linked glycan of asialo-fetuin bifidobacterium longum 111.0 111.0 1 PMID:35605676 -3.2.1.97 tn antigen bifidobacterium bifidum 47.6 47.6 1 PMID:22090027 -3.2.1.98 maltononaose bacillus licheniformis 12.86 12.86 1 PMID:24440349 -3.2.1.99 1,5-alpha-l-arabinan caldicellulosiruptor saccharolyticus dsm 8903 50.0 50.0 1 PMID:19458916 -3.2.1.99 linear 1,5-alpha-l-arabinan bacillus subtilis 191.6 191.6 1 PMID:20883454 -3.2.1.99 linear 1,5-alpha-l-arabinan paenibacillus polymyxa 68.7 68.7 1 PMID:25077565 -3.2.1.99 linear arabinan pseudothermotoga thermarum 349.3 349.3 1 PMID:24886412 -3.2.2.1 2'-o-methyluridine lentilactobacillus buchneri 0.49 0.49 1 PMID:27180876 -3.2.2.1 2-aminopurine riboside trypanosoma brucei brucei 0.57 0.57 1 PMID:20825170 -3.2.2.1 2-aminopurine riboside trypanosoma vivax 0.57 0.57 1 PMID:18519562 -3.2.2.1 3-deazaadenosine trypanosoma brucei brucei 0.009 0.009 1 PMID:20825170 -3.2.2.1 4-nitrophenyl beta-d-ribofuranoside trypanosoma brucei brucei 0.03 0.03 1 PMID:20825170 -3.2.2.1 4-nitrophenylriboside caenorhabditis elegans 0.039 0.039 1 PMID:28218438 -3.2.2.1 5'-deoxyadenosine trypanosoma brucei brucei 0.078 0.078 1 PMID:20825170 -3.2.2.1 7-methyl guanosine trypanosoma vivax 3.4 2.235 2 PMID:16630632;PMID:18519562 -3.2.2.1 7-methylguanosine caenorhabditis elegans 1.09 1.09 1 PMID:28218438 -3.2.2.1 7-methylguanosine trypanosoma brucei brucei 5.2 5.2 1 PMID:20825170 -3.2.2.1 adenosine caenorhabditis elegans 0.78 0.599 2 PMID:12777783;PMID:28218438 -3.2.2.1 adenosine saccharolobus solfataricus 3.8 3.8 1 PMID:19121283 -3.2.2.1 adenosine salmonella enterica 2.1 2.1 1 PMID:15784179 -3.2.2.1 adenosine trypanosoma brucei 17.3 17.3 1 PMID:23897478 -3.2.2.1 adenosine trypanosoma brucei brucei 0.237 0.237 1 PMID:20825170 -3.2.2.1 adenosine trypanosoma vivax 2.6 2.0300000000000002 2 PMID:11292348;PMID:16630632 -3.2.2.1 cytidine caenorhabditis elegans 0.5 0.5 1 PMID:12777783 -3.2.2.1 cytidine salmonella enterica 7.8 7.8 1 PMID:15784179 -3.2.2.1 cytidine trypanosoma brucei brucei 0.52 0.52 1 PMID:20825170 -3.2.2.1 cytidine trypanosoma vivax 0.338 0.338 2 PMID:11292348;PMID:16630632 -3.2.2.1 ethenoadenosine trypanosoma brucei brucei 6.9 6.9 1 PMID:20825170 -3.2.2.1 guanosine caenorhabditis elegans 0.84 0.4915 2 PMID:12777783;PMID:28218438 -3.2.2.1 guanosine saccharolobus solfataricus 29.1 29.1 1 PMID:19121283 -3.2.2.1 guanosine trypanosoma brucei 37.3 37.3 1 PMID:23897478 -3.2.2.1 guanosine trypanosoma brucei brucei 37.6 19.45 2 PMID:20825170 -3.2.2.1 guanosine trypanosoma vivax 2.3 2.3 3 PMID:11292348;PMID:16630632;PMID:18519562 -3.2.2.1 inosine bacillus thuringiensis 48.9 48.9 1 PMID:18451042 -3.2.2.1 inosine caenorhabditis elegans 0.79 0.49650000000000005 2 PMID:12777783;PMID:28218438 -3.2.2.1 inosine crithidia fasciculata 32.0 32.0 1 PMID:1939115 -3.2.2.1 inosine physcomitrium patens 6.0 6.0 1 PMID:24170203 -3.2.2.1 inosine saccharolobus solfataricus 23.3 17.45 2 PMID:19121283;PMID:22551416 -3.2.2.1 inosine salmonella enterica 9.0 8.55 2 PMID:15784179 -3.2.2.1 inosine trypanosoma brucei 61.0 47.5 2 PMID:23897478;PMID:8702965 -3.2.2.1 inosine trypanosoma brucei brucei 8.0 8.0 1 PMID:20825170 -3.2.2.1 inosine trypanosoma vivax 5.49 5.34 2 PMID:11292348 -3.2.2.1 inosine zea mays 7.2 7.2 1 PMID:24170203 -3.2.2.1 p-nitrophenylriboside trypanosoma vivax 0.206 0.206 1 PMID:11292348 -3.2.2.1 purine ribonucleoside trypanosoma vivax 3.9 3.9 1 PMID:16630632 -3.2.2.1 purine riboside trypanosoma brucei brucei 0.248 0.248 1 PMID:20825170 -3.2.2.1 uridine caenorhabditis elegans 0.0022 0.0022 1 PMID:12777783 -3.2.2.1 uridine salmonella enterica 46.0 46.0 1 PMID:15784179 -3.2.2.1 uridine trypanosoma brucei brucei 0.0038 0.0038 1 PMID:20825170 -3.2.2.1 uridine trypanosoma vivax 0.022 0.022 1 PMID:11292348 -3.2.2.1 xanthosine caenorhabditis elegans 0.029 0.029 1 PMID:12777783 -3.2.2.1 xanthosine physcomitrium patens 7.0 7.0 1 PMID:24170203 -3.2.2.1 xanthosine salmonella enterica 62.0 44.15 2 PMID:15784179 -3.2.2.1 xanthosine trypanosoma brucei brucei 6.2 6.2 1 PMID:20825170 -3.2.2.1 xanthosine zea mays 6.2 6.2 1 PMID:24170203 -3.2.2.15 hypoxanthine-containing double-stranded dna pedobacter heparinus 0.004 0.004 1 PMID:28049757 -3.2.2.15 uracil-containing double-stranded dna pedobacter heparinus 0.57 0.298 2 PMID:28049757 -3.2.2.15 xanthine-containing double-stranded dna pedobacter heparinus 0.059 0.059 1 PMID:28049757 -3.2.2.16 5'-methylthioadenosine arabidopsis thaliana 18.7 18.7 3 PMID:18342331 -3.2.2.16 5'-methylthioadenosine escherichia coli 4.0 2.3 3 PMID:17059210;PMID:18453700;PMID:22931458 -3.2.2.16 5'-methylthioadenosine salmonella enterica 20.0 20.0 1 PMID:22931458 -3.2.2.16 5'-methylthioadenosine staphylococcus aureus 0.00973 0.00973 1 PMID:18453700 -3.2.2.16 5'-methylthioadenosine streptococcus pneumoniae 0.25 0.25 1 PMID:17059210 -3.2.2.16 5'-methylthioadenosine vibrio cholerae serotype o1 4.2 3.1 2 PMID:19270684;PMID:22931458 -3.2.2.16 s-adenosyl-l-homocysteine brucella melitensis 7.1 7.1 1 PMID:24657441 -3.2.2.16 s-adenosyl-l-homocysteine escherichia coli 2.1 2.1 1 PMID:17059210 -3.2.2.16 s-adenosyl-l-homocysteine helicobacter pylori 1.8 1.8 1 PMID:23148563 -3.2.2.16 s-adenosyl-l-homocysteine streptococcus pneumoniae 0.37 0.37 1 PMID:17059210 -3.2.2.16 s-methyl-5'-thioadenosine brucella melitensis 8.8 8.8 1 PMID:24657441 -3.2.2.16 s-methyl-5'-thioadenosine burkholderia thailandensis 1.8 1.8 1 PMID:23198993 -3.2.2.16 s-methyl-5'-thioadenosine escherichia coli 2.3 1.3099999999999998 2 PMID:22931458;PMID:24502544 -3.2.2.16 s-methyl-5'-thioadenosine helicobacter pylori 3.8 3.8 1 PMID:23148563 -3.2.2.16 s-methyl-5'-thioadenosine salmonella enterica 20.0 20.0 1 PMID:22931458 -3.2.2.16 s-methyl-5'-thioadenosine staphylococcus aureus 10.2 10.2 1 PMID:24502544 -3.2.2.16 s-methyl-5'-thioadenosine vibrio cholerae 0.18 0.18 1 PMID:24502544 -3.2.2.16 s-methyl-5'-thioadenosine vibrio cholerae serotype o1 4.2 4.2 1 PMID:22931458 -3.2.2.2 adenosine saccharolobus solfataricus 3.8 3.8 1 PMID:19121283 -3.2.2.2 guanosine saccharolobus solfataricus 29.1 29.1 1 PMID:19121283 -3.2.2.2 inosine bacillus thuringiensis 48.9 48.9 1 PMID:18451042 -3.2.2.2 inosine saccharolobus solfataricus 23.3 23.3 1 PMID:19121283 -3.2.2.21 1,n6-ethenoadenine residues in alkylated dna homo sapiens 0.000833 0.000833 1 PMID:12016206 -3.2.2.21 1,n6-ethenoadenine residues in alkylated dna mus musculus 0.0167 0.0167 1 PMID:9425080 -3.2.2.21 duplex oligonucleotide substrate containing ethenoadenine and hypoxanthine escherichia coli 0.00125 0.00125 1 PMID:21491902 -3.2.2.21 hypoxanthine homo sapiens 0.0033 0.0033 1 PMID:18191412 -3.2.2.22 5'-dg1dc2dg3dc4dg5a6dg7da8dg9dc10dg11dc12-3' ricinus communis 0.0083 0.0083 1 PMID:15109249 -3.2.2.22 5'-dg1dc2dg3dc4dg5da6dg7a8dg9dc10dg11dc12-3' ricinus communis 0.015 0.015 1 PMID:15109249 -3.2.2.22 5'-dg1dc2dg3dc4dg5da6g7da8dg9dc10dg11dc12-3' ricinus communis 0.0015 0.0015 1 PMID:15109249 -3.2.2.22 5'-dg1dc2dg3dc4g5da6dg7da8dg9dc10dg11dc12-3' ricinus communis 0.0038 0.0038 1 PMID:15109249 -3.2.2.22 5'-g1c2g3c4dg5a6dg7a8g9c10g11c12-3' ricinus communis 0.0007 0.0007 1 PMID:15109249 -3.2.2.22 5'-g1c2g3c4dg5a6g7a8g9c10g11c12-3' ricinus communis 0.005 0.005 1 PMID:15109249 -3.2.2.22 5'-g1c2g3c4dg5a6g7da8g9c10g11c12-3' ricinus communis 0.01 0.01 1 PMID:15109249 -3.2.2.22 5'-g1c2g3c4g5a6dg7a8g9c10g11c12-3' ricinus communis 0.011 0.011 1 PMID:15109249 -3.2.2.22 5'-g1c2g3c4g5a6g7a8g9c10g11c12-3' ricinus communis 1.68 1.68 1 PMID:15109249 -3.2.2.22 5'-g1c2g3c4g5a6g7da8g9c10g11c12-3' ricinus communis 0.055 0.055 1 PMID:15109249 -3.2.2.22 5'-g1c2g3c4g5a6g7ma8g9c10g11c12-3' ricinus communis 0.085 0.085 1 PMID:15109249 -3.2.2.22 5'-g1c2g3c4g5a6mg7a8g9c10g11c12-3' ricinus communis 0.005 0.005 1 PMID:15109249 -3.2.2.22 5'-g1c2g3c4g5da6g7a8g9c10g11c12-3' ricinus communis 27.67 27.67 1 PMID:15109249 -3.2.2.22 5'-g1c2g3c4g5ma6g7a8g9c10g11c12-3' ricinus communis 0.07 0.07 1 PMID:15109249 -3.2.2.22 5'-g1c2g3c4mg5a6g7a8g9c10g11c12-3' ricinus communis 0.001 0.001 1 PMID:15109249 -3.2.2.22 a-10 rna saponaria officinalis 7.33 3.694 2 PMID:19764816 -3.2.2.22 a-14 2-da stem-loop rna/dna hybrid ricinus communis 18.5 18.5 1 PMID:19364139 -3.2.2.22 cyclic dg-(n-benzyl-aza-deoxyribosyl)-dgda ricinus communis 0.018 0.018 1 PMID:17417841 -3.2.2.22 cyclic dgdadgda ricinus communis 0.108 0.108 1 PMID:17417841 -3.2.2.22 cyclic gdaga ricinus communis 0.018 0.018 1 PMID:17417841 -3.2.2.22 cyclic oxime gaga saponaria officinalis 5.01 5.01 1 PMID:19764816 -3.2.2.22 cyclic phosphorothioyl dgdadgda ricinus communis 0.15 0.15 1 PMID:17417841 -3.2.2.22 dgdadgda ricinus communis 0.0045 0.0045 1 PMID:17417841 -3.2.2.22 dgdcdgdcdgdadgdadgdcdgdc ricinus communis 0.0083 0.0083 1 PMID:17417841 -3.2.2.22 gdaga ricinus communis 0.003 0.003 1 PMID:17417841 -3.2.2.22 linear gaga saponaria officinalis 4.88 4.88 1 PMID:19764816 -3.2.2.22 poly(a) saponaria officinalis 3.05 1.02 3 PMID:19764816;PMID:8912688 -3.2.2.22 rrna escherichia coli 12.8 10.7 5 PMID:9403966 -3.2.2.22 rrna ricinus communis 29.6 14.80025 4 PMID:17626843;PMID:3288622 -3.2.2.22 rrna saponaria officinalis 62.0 62.0 1 PMID:17626843 -3.2.2.22 sarcin/ricin domains of escherichia coli 23s rrna ricinus communis 0.0012 0.0012 1 PMID:19014981 -3.2.2.22 sarcin/ricin domains of rattus norvegicus 28s rrna ricinus communis 0.0018 0.0018 1 PMID:19014981 -3.2.2.22 stem-loop substrate a-10 ricinus communis 0.078 0.078 1 PMID:19364139 -3.2.2.23 13mer oligonucleotide duplex containing 8-oxoguanine escherichia coli 0.0283 0.0175 6 PMID:18172202;PMID:30032016 -3.2.2.23 23mer oligonucleotide duplex containing 8-oxoguanine escherichia coli 1.7 1.7 1 PMID:26553802 -3.2.2.23 5,6-dihydrouracil-dna homo sapiens 0.02 0.02 1 PMID:19916941 -3.2.2.23 8-oxo-7,8-dihydroguanine:cyt oligodeoxynucleotide homo sapiens 0.0005 0.0005 1 PMID:19674107 -3.2.2.23 dna escherichia coli 0.0568 0.05 3 PMID:11814345;PMID:31120733;PMID:9125531 -3.2.2.23 dna containing 5,6-dihydrouracil escherichia coli 0.011 0.011 1 PMID:14607836 -3.2.2.23 dna containing 7-deaza-2'-deoxyguanosine escherichia coli 0.053 0.053 1 PMID:17536801 -3.2.2.23 dna containing 7-deaza-2'-deoxyguanosine homo sapiens 0.00078 0.00078 1 PMID:17536801 -3.2.2.23 dna containing 7-hydro-8-oxoguanine residues escherichia coli 0.025 0.02175 2 PMID:11814345;PMID:9125531 -3.2.2.23 dna containing 7-methyl-8-oxo-2'-deoxyguanosine escherichia coli 0.00051 0.00051 1 PMID:17536801 -3.2.2.23 dna containing 7-methyl-8-oxo-2'-deoxyguanosine homo sapiens 0.00025 0.00025 1 PMID:17536801 -3.2.2.23 dna containing 8-hydroxyguanine residues escherichia coli 0.03 0.018585 2 PMID:10671534;PMID:9826758 -3.2.2.23 dna containing 8-oxo-2'-deoxyguanosine escherichia coli 0.066 0.066 1 PMID:17536801 -3.2.2.23 dna containing 8-oxo-2'-deoxyguanosine homo sapiens 0.043 0.043 1 PMID:17536801 -3.2.2.23 dna containing 8-oxo-guanine residues escherichia coli 0.005 0.005 1 PMID:14607836 -3.2.2.23 dna containing 8-oxo-guanine residues mispaired to adenine escherichia coli 0.00011 0.00011 1 PMID:14607836 -3.2.2.23 dna containing 8-oxo-guanine residues mispaired to guanine escherichia coli 0.0035 0.0035 1 PMID:14607836 -3.2.2.23 dna containing 8-oxo-guanine residues mispaired to thymine escherichia coli 0.0047 0.0047 1 PMID:14607836 -3.2.2.23 dna containing 8-thio-2'-deoxyguanosine escherichia coli 0.00045 0.00045 1 PMID:17536801 -3.2.2.23 dna containing 8-thio-2'-deoxyguanosine homo sapiens 0.00045 0.00045 1 PMID:17536801 -3.2.2.23 dna containing a broken link a(+2)-p(+2) escherichia coli 0.025 0.025 1 PMID:31120733 -3.2.2.23 dna containing a broken link a(-2)-p(-2) escherichia coli 0.0138 0.0138 1 PMID:31120733 -3.2.2.23 dna containing a broken link c(+1)-p(0) escherichia coli 0.045 0.045 1 PMID:31120733 -3.2.2.23 dna containing a broken link c(-1)-p(-2) escherichia coli 0.00367 0.00367 1 PMID:31120733 -3.2.2.23 dna containing a broken link c(0)-p(0) escherichia coli 0.0108 0.0108 1 PMID:31120733 -3.2.2.23 dna containing a broken link ddt(-2)-p(-3) escherichia coli 0.0092 0.0092 1 PMID:31120733 -3.2.2.23 dna containing a broken link g(+1)-p(+1) escherichia coli 0.014 0.014 1 PMID:31120733 -3.2.2.23 dna containing a broken link g(-1)-p(-1) escherichia coli 0.0283 0.0283 1 PMID:31120733 -3.2.2.23 dna containing a broken link g(-3)-p(-3) escherichia coli 0.0183 0.0183 1 PMID:31120733 -3.2.2.23 dna containing a broken link p(+1)-a(+2) escherichia coli 0.0113 0.0113 1 PMID:31120733 -3.2.2.23 dna containing a broken link p(+1)-c(+1) escherichia coli 0.0467 0.0467 1 PMID:31120733 -3.2.2.23 dna containing a broken link p(+2)-a(+3) escherichia coli 0.022 0.022 1 PMID:31120733 -3.2.2.23 dna containing a broken link p(+2)-t(+2) escherichia coli 0.0233 0.0233 1 PMID:31120733 -3.2.2.23 dna containing a broken link p(-1)-c(0) escherichia coli 0.0133 0.0133 1 PMID:31120733 -3.2.2.23 dna containing a broken link p(-2)-g(-1) escherichia coli 0.01 0.01 1 PMID:31120733 -3.2.2.23 dna containing a broken link p(-3)-a(-2) escherichia coli 0.015 0.015 1 PMID:31120733 -3.2.2.23 dna containing a broken link p(-3)-c(-3) escherichia coli 0.0137 0.0137 1 PMID:31120733 -3.2.2.23 dna containing a broken link p(0)-g(+1) escherichia coli 0.0167 0.0167 1 PMID:31120733 -3.2.2.23 dna containing a broken link t(+2)-p(+1) escherichia coli 0.02 0.02 1 PMID:31120733 -3.2.2.23 dna containing a broken link t(+3)-p(+2) escherichia coli 0.0217 0.0217 1 PMID:31120733 -3.2.2.23 dna containing a broken link t(-2)-p(-3) escherichia coli 0.0147 0.0147 1 PMID:31120733 -3.2.2.23 dna containing ring-opened n7-methylguanine residues escherichia coli 0.085 0.00833 3 PMID:10671534;PMID:9125531;PMID:9826758 -3.2.2.26 5'-deoxyadenosine campylobacter jejuni subsp. jejuni 0.92 0.92 1 PMID:30339406 -3.2.2.26 5'-methylthioadenosine campylobacter jejuni subsp. jejuni 0.8 0.8 1 PMID:30339406 -3.2.2.26 6-amino-6-deoxyfutalosine campylobacter jejuni 0.53 0.53 1 PMID:21489995 -3.2.2.26 6-amino-6-deoxyfutalosine campylobacter jejuni subsp. jejuni 0.27 0.27 1 PMID:30339406 -3.2.2.26 adenosine campylobacter jejuni subsp. jejuni 0.3 0.3 1 PMID:30339406 -3.2.2.26 futalosine thermus thermophilus 1.02 1.02 1 PMID:19420717 -3.2.2.26 s-5'-adenosyl-l-homocysteine campylobacter jejuni subsp. jejuni 0.55 0.55 1 PMID:30339406 -3.2.2.27 5-hydroxymethyluracil-mismatched double-stranded dna with u-a mismatch homo sapiens 0.015 0.015 1 PMID:12161446 -3.2.2.27 5-hydroxymethyluracil-mismatched double-stranded dna with u-g mismatch homo sapiens 0.04 0.04 1 PMID:12161446 -3.2.2.27 5-hydroxymethyluracil-mismatched single-stranded dna homo sapiens 0.098 0.098 1 PMID:12161446 -3.2.2.27 double stranded dna containing g-u mismatch thermus thermophilus 0.23 0.23 1 PMID:28397787 -3.2.2.27 dump dna aliivibrio salmonicida 174.0 174.0 1 PMID:20124707 -3.2.2.27 dump dna vibrio cholerae 293.0 293.0 1 PMID:20124707 -3.2.2.27 fu-containing 10 nucleotide dna sequence 5'-ggagafuctcc-3' with opposing c, t, a, or g homo sapiens 0.0003 0.0003 1 PMID:19365746 -3.2.2.27 ggacttcuctcctttccaga/tctggaaaggagggaagtcc duplex orthopoxvirus vaccinia 7.3 7.3 1 PMID:37298065 -3.2.2.27 tcccttcuctcctttccttc/tcccttcuctcctttccttc duplex orthopoxvirus vaccinia 5.8 5.8 1 PMID:37298065 -3.2.2.27 uracil-containing calf thymus dna gadus morhua 20.68 10.28 3 PMID:21959147 -3.2.2.27 uracil-containing calf thymus dna homo sapiens 10.78 5.33 3 PMID:21959147 -3.2.2.27 uracil-containing double-stranded dna archaeoglobus fulgidus 0.33 0.33 1 PMID:22646210 -3.2.2.27 uracil-containing single-stranded dna archaeoglobus fulgidus 0.18 0.18 1 PMID:22646210 -3.2.2.27 uracil-mismatched double-stranded dna archaeoglobus fulgidus 1.8 0.29900000000000004 6 PMID:10777501;PMID:11738943;PMID:20453094 -3.2.2.27 uracil-mismatched double-stranded dna deinococcus radiodurans 15.58 15.58 1 PMID:16041069 -3.2.2.27 uracil-mismatched double-stranded dna monkeypox virus 4.67 1.83 7 PMID:17910420 -3.2.2.27 uracil-mismatched double-stranded dna with a-u mismatch + chlamydia pneumoniae 5.9 5.9 1 PMID:15039065 -3.2.2.27 uracil-mismatched double-stranded dna with u-a mismatch homo sapiens 2.28 1.166 2 PMID:12161446 -3.2.2.27 uracil-mismatched double-stranded dna with u-g mismatch homo sapiens 5.57 0.055 3 PMID:12161446;PMID:15466595 -3.2.2.27 uracil-mismatched double-stranded dna with u-g mismatch xenopus laevis 0.0014 0.0014 1 PMID:10074426 -3.2.2.27 uracil-mismatched single-stranded dna archaeoglobus fulgidus 0.917 0.55 3 PMID:10777501;PMID:11738943 -3.2.2.27 uracil-mismatched single-stranded dna homo sapiens 46.1 23.195 2 PMID:12161446 -3.2.2.27 uracil-mismatched single-stranded dna thermus thermophilus 0.17 0.17 1 PMID:14556741 -3.2.2.27 uracil-mismatched single-stranded dna xenopus laevis 2.5 2.5 1 PMID:10074426 -3.2.2.28 3,n4-ethenocytosine-mismatched double-stranded dna escherichia coli 0.016 0.016 1 PMID:9671708 -3.2.2.28 hydroxymethyluracil-containing double-stranded dna deinococcus radiodurans 0.00035 0.00023 3 PMID:35607831 -3.2.2.28 uracil-guanine-mismatched double-stranded dna escherichia coli 9.31 9.31 1 PMID:33254084 -3.2.2.28 uracil-mismatched double-stranded dna deinococcus radiodurans 0.00277 0.00087 3 PMID:35607831 -3.2.2.28 uracil-mismatched double-stranded dna escherichia coli 0.0028 0.0028 1 PMID:9671708 -3.2.2.29 3,n4-ethenocytosine-mismatched double-stranded dna homo sapiens 0.000153 0.000153 1 PMID:9671708 -3.2.2.29 5-chlorouracil-mismatched double-stranded dna homo sapiens 2.1 2.1 1 PMID:16984202 -3.2.2.29 5-fluorouracil-mismatched double-stranded dna homo sapiens 3.7 3.7 1 PMID:16984202 -3.2.2.29 thymine-mismatched double-stranded dna homo sapiens 0.0036 0.0018074999999999999 2 PMID:16984202;PMID:9671708 -3.2.2.29 uracil-mismatched double-stranded dna homo sapiens 0.043 0.021675 2 PMID:16984202;PMID:9671708 -3.2.2.3 adenosine escherichia coli 1.15 1.15 1 PMID:24473221 -3.2.2.3 adenosine limosilactobacillus reuteri 118.0 91.5 2 PMID:38203708 -3.2.2.3 adenosine zea mays 0.4 0.29000000000000004 2 PMID:24170203 -3.2.2.3 cytidine escherichia coli 1.12 1.12 1 PMID:24473221 -3.2.2.3 cytidine limosilactobacillus reuteri 112.0 85.0 2 PMID:38203708 -3.2.2.3 inosine escherichia coli 4.31 4.31 1 PMID:24473221 -3.2.2.3 inosine limosilactobacillus reuteri 30.0 24.0 2 PMID:38203708 -3.2.2.3 inosine zea mays 4.1 2.355 2 PMID:24170203 -3.2.2.3 nicotinamide riboside saccharomyces cerevisiae 23.4 23.4 1 PMID:19001417 -3.2.2.3 nicotinic acid riboside saccharomyces cerevisiae 1.8 1.8 1 PMID:19001417 -3.2.2.3 nicotinic acid riboside methyl ester saccharomyces cerevisiae 2.3 2.3 1 PMID:19001417 -3.2.2.3 ribothymidine escherichia coli 1.29 1.29 1 PMID:24473221 -3.2.2.3 uridine escherichia coli 10.85 10.85 1 PMID:24473221 -3.2.2.3 uridine limosilactobacillus reuteri 167.0 134.0 3 PMID:38154259;PMID:38203708 -3.2.2.3 uridine saccharomyces cerevisiae 20.0 20.0 1 PMID:19001417 -3.2.2.3 uridine zea mays 28.7 23.8 3 PMID:24170203;PMID:38044809 -3.2.2.3 xanthosine escherichia coli 6.3 6.3 1 PMID:24473221 -3.2.2.3 xanthosine limosilactobacillus reuteri 40.0 23.5 2 PMID:38203708 -3.2.2.3 xanthosine zea mays 6.4 4.6 3 PMID:24170203;PMID:38044809 -3.2.2.30 5'-deoxyadenosine campylobacter jejuni subsp. jejuni serotype o:2 0.92 0.92 1 PMID:30339406 -3.2.2.30 5'-methylthioadenosine campylobacter jejuni subsp. jejuni serotype o:2 0.8 0.8 1 PMID:30339406 -3.2.2.30 6-amino-6-deoxyfutalosine campylobacter jejuni 0.53 0.53 1 PMID:21489995 -3.2.2.30 6-amino-6-deoxyfutalosine campylobacter jejuni subsp. jejuni serotype o:2 0.27 0.27 1 PMID:30339406 -3.2.2.30 adenosine campylobacter jejuni subsp. jejuni serotype o:2 0.3 0.3 1 PMID:30339406 -3.2.2.30 s-5'-adenosyl-l-homocysteine campylobacter jejuni subsp. jejuni serotype o:2 0.55 0.55 1 PMID:30339406 -3.2.2.31 dna containing a 5-hydroxyuracil/adenine mismatch escherichia coli 2.5e-05 2.5e-05 1 PMID:16201966 -3.2.2.4 amp azotobacter vinelandii 62.0 61.0 2 PMID:3485632;PMID:40976;PMID:6796578 -3.2.2.4 nmn azotobacter vinelandii 2.0 2.0 1 PMID:3485632 -3.2.2.5 nad+ aplysia californica 442.0 442.0 1 PMID:1650254 -3.2.2.5 nad+ aspergillus fumigatus 1962.0 1962.0 1 PMID:33712585 -3.2.2.5 nad+ bacillus subtilis 0.358 0.358 1 PMID:6246385 -3.2.2.5 nad+ bos taurus 53.6 53.6 1 PMID:8391778 -3.2.2.5 nad+ deinagkistrodon acutus 22.3 22.3 1 PMID:18952139 -3.2.2.5 nad+ streptococcus pyogenes 8390.0 4195.0185 2 PMID:20018886;PMID:23689507 -3.2.2.5 nadp+ aspergillus fumigatus 418.0 418.0 1 PMID:33712585 -3.2.2.6 nad+ bos taurus 57.9 57.9 1 PMID:24721563 -3.2.2.7 adenosine lupinus luteus 0.06 0.06 1 * -3.2.2.8 4-nitrophenyl beta-d-ribofuranoside leishmania braziliensis 344.0 344.0 1 * -3.2.2.8 4-nitrophenyl ribopyranoside escherichia coli k-12 39.0 39.0 1 PMID:16411753 -3.2.2.8 5-bromouridine escherichia coli 30.8 30.8 1 PMID:15130467 -3.2.2.8 5-fluorouridine escherichia coli 14.7 14.7 1 PMID:15130467 -3.2.2.8 5-iodouridine escherichia coli 42.7 42.7 1 PMID:15130467 -3.2.2.8 5-methyluridine escherichia coli 25.5 25.5 1 PMID:15130467 -3.2.2.8 adenosine escherichia coli k-12 0.0154 0.0154 1 PMID:16411753 -3.2.2.8 adenosine leishmania braziliensis 0.039 0.039 1 * -3.2.2.8 cytidine escherichia coli 11.6 11.6 1 PMID:15130467 -3.2.2.8 cytidine escherichia coli k-12 11.6 11.6 1 PMID:16411753 -3.2.2.8 cytidine leishmania braziliensis 0.066 0.066 1 * -3.2.2.8 cytidine saccharolobus solfataricus 39.4 39.4 1 PMID:18355316 -3.2.2.8 guanosine escherichia coli k-12 0.0056 0.0056 1 PMID:16411753 -3.2.2.8 inosine escherichia coli 0.086 0.086 1 PMID:18361502 -3.2.2.8 inosine escherichia coli k-12 0.043 0.043 1 PMID:16411753 -3.2.2.8 inosine leishmania braziliensis 11.2 11.2 1 * -3.2.2.8 uridine escherichia coli 5.4 5.050000000000001 2 PMID:15130467;PMID:18361502 -3.2.2.8 uridine escherichia coli k-12 13.9 13.9 1 PMID:16411753 -3.2.2.8 uridine leishmania braziliensis 5.1 5.1 1 * -3.2.2.8 uridine saccharolobus solfataricus 7.1 7.1 1 PMID:18355316 -3.2.2.9 5'-deoxyadenosine borreliella burgdorferi 2.7 1.53 3 PMID:31669585 -3.2.2.9 5'-deoxyadenosine mycobacterium tuberculosis 0.47 0.47 1 PMID:27019223 -3.2.2.9 5'-methylthioadenosine arabidopsis thaliana 2.0 2.0 1 PMID:18342331 -3.2.2.9 5'-methylthioadenosine campylobacter jejuni 2.7 2.7 1 PMID:21489995 -3.2.2.9 5'-methylthioadenosine escherichia coli 4.0 3.5 2 PMID:16101288;PMID:17059210 -3.2.2.9 5'-methylthioadenosine helicobacter pylori 4.92 4.92 1 PMID:20954236 -3.2.2.9 5'-methylthioadenosine mycobacterium tuberculosis 0.023 0.023 1 PMID:27019223 -3.2.2.9 5'-methylthioadenosine streptococcus pneumoniae 0.25 0.25 1 PMID:17059210 -3.2.2.9 5'-methylthioadenosine vibrio cholerae serotype o1 2.0 2.0 1 PMID:19270684 -3.2.2.9 6-amino-6-deoxyfutalosine campylobacter jejuni 0.53 0.53 1 PMID:21489995 -3.2.2.9 s-adenosyl-l-homocysteine borreliella burgdorferi 1.75 1.57 3 PMID:31669585 -3.2.2.9 s-adenosyl-l-homocysteine brucella melitensis 7.1 7.1 1 PMID:24657441 -3.2.2.9 s-adenosyl-l-homocysteine burkholderia thailandensis 0.00021 0.00021 1 PMID:23198993 -3.2.2.9 s-adenosyl-l-homocysteine escherichia coli 2.6 2.1 3 PMID:16101288;PMID:17059210;PMID:18453700 -3.2.2.9 s-adenosyl-l-homocysteine helicobacter pylori 1.8 1.8 1 PMID:23148563 -3.2.2.9 s-adenosyl-l-homocysteine mycobacterium tuberculosis 0.004 0.004 1 PMID:27019223 -3.2.2.9 s-adenosyl-l-homocysteine staphylococcus aureus 0.00873 0.00873 1 PMID:18453700 -3.2.2.9 s-adenosyl-l-homocysteine streptococcus pneumoniae 0.37 0.37 1 PMID:17059210 -3.2.2.9 s-adenosyl-l-homocysteine vibrio cholerae 0.18 0.18 1 PMID:25806409 -3.2.2.9 s-adenosyl-l-homocysteine vibrio cholerae serotype o1 0.5 0.5 1 PMID:19270684 -3.2.2.9 s-adenosylhomocysteine vibrio cholerae serotype o1 0.5 0.5 1 PMID:19270684 -3.2.2.9 s-methyl-5'-thioadenosine borreliella burgdorferi 1.85 1.78 3 PMID:31669585 -3.2.2.9 s-methyl-5'-thioadenosine escherichia coli 39.4 20.65 2 PMID:35969806 -3.2.2.9 s-methyl-5'-thioadenosine helicobacter pylori 39.4 26.1 2 PMID:35969806 -3.3.2.1 (+/-)-3-[(1-carboxyethenyl)oxy]-2-hydroxy-6-cyclohexene-1-carboxylic acid escherichia coli 5.17 5.17 1 PMID:2139796 -3.3.2.1 (+/-)-3-[(1-carboxyethenyl)oxy]-cyclohepta-1,6-diene-1-carboxylate escherichia coli 9.0 9.0 1 PMID:2139796 -3.3.2.1 (+/-)-3-[(carboxyethenyl)oxy]-1-cyclohexene-1-carboxylic acid escherichia coli 21.7 21.7 1 PMID:2139796 -3.3.2.1 (+/-)-cis-3-[(carboxyethenyl)oxy]-4-cyclohexene-1-carboxylic acid escherichia coli 16.3 16.3 1 PMID:2139796 -3.3.2.1 chorismate escherichia coli 217.0 217.0 1 PMID:2139796 -3.3.2.1 chorismate pseudomonas aeruginosa 0.085 0.085 1 PMID:16036918 -3.3.2.1 isochorismate escherichia coli 10.0 10.0 1 PMID:2139796 -3.3.2.1 isochorismate pseudomonas aeruginosa 1.06 1.06 1 PMID:16036918 -3.3.2.10 (10r)-hydroxy-(11s,12s)-epoxy-(5z,8z,14z)-eicosatrienoic acid homo sapiens 0.1 0.1 1 PMID:21217101 -3.3.2.10 (10r)-hydroxy-(11s,12s)-epoxy-(5z,8z,14z)-eicosatrienoic acid rattus norvegicus 0.6 0.6 1 PMID:21217101 -3.3.2.10 (8r)-hydroxy-(11s,12s)-epoxy-(5z,9e,14z)-eicosatrienoic acid homo sapiens 0.42 0.42 1 PMID:21217101 -3.3.2.10 (8r)-hydroxy-(11s,12s)-epoxy-(5z,9e,14z)-eicosatrienoic acid rattus norvegicus 1.88 1.88 1 PMID:21217101 -3.3.2.10 (r)-p-nitrostyrene oxide aspergillus niger 16.4 16.4 1 PMID:10406946 -3.3.2.10 (r)-styrene oxide trichoderma reesei 336.0 336.0 1 PMID:27177457 -3.3.2.10 (r,s)-4-nitrostyrene oxide aspergillus niger 13.9 13.9 1 PMID:10406946 -3.3.2.10 (s)-4-nitrostyrene oxide aspergillus niger 1.7 1.7 1 PMID:10406946 -3.3.2.10 (s)-styrene oxide trichoderma reesei 265.0 265.0 1 PMID:27177457 -3.3.2.10 1-myristoyl-sn-glycerol 3-phosphate homo sapiens 0.15 0.15 1 PMID:24771868 -3.3.2.10 13,14-epoxy-docosapentaenoic acid homo sapiens 2.85 1.465 2 PMID:34066758 -3.3.2.10 14,15-epoxyeicosatrienoic acid homo sapiens 5.0 3.0 3 PMID:24771868;PMID:34066758 -3.3.2.10 2,3-epoxy-1,3-diphenyl-propane arabidopsis thaliana 1.64 1.64 1 PMID:10860549 -3.3.2.10 2,3-epoxy-1,3-diphenyl-propane homo sapiens 4.3 4.3 1 PMID:10860549 -3.3.2.10 2,3-epoxy-1,3-diphenyl-propane mus musculus 18.0 18.0 1 PMID:10860549 -3.3.2.10 2,3-epoxy-1,3-diphenyl-propane rattus norvegicus 12.0 12.0 1 PMID:10860549 -3.3.2.10 2,3-epoxy-1,3-diphenyl-propane solanum tuberosum 4.76 4.76 1 PMID:10860549 -3.3.2.10 4-nitrophenyl (2r,3r)-2,3-epoxy-3-(4-nitrophenyl)propyl carbonate mus musculus 4.8 4.8 1 PMID:8432382 -3.3.2.10 4-nitrophenyl (2r,3r)-2,3-epoxy-3-phenylpropyl carbonate mus musculus 26.7 26.7 1 PMID:8432382 -3.3.2.10 4-nitrophenyl (2s,3s)-2,3-epoxy-3-(4-nitrophenyl)propyl carbonate mus musculus 7.7 7.7 1 PMID:8432382 -3.3.2.10 4-nitrophenyl (2s,3s)-2,3-epoxy-3-phenylpropyl carbonate mus musculus 15.8 15.8 1 PMID:8432382 -3.3.2.10 8,9-epoxyeicosatrienoic acid homo sapiens 0.56 0.29500000000000004 2 PMID:34066758 -3.3.2.10 attophos homo sapiens 0.0131 0.0131 1 PMID:24771868 -3.3.2.10 hepoxilin a3 homo sapiens 7.3 3.657 2 PMID:34066758 -3.3.2.10 p-nitrophenyl phosphate homo sapiens 0.06 0.06 1 PMID:12574510 -3.3.2.10 threo-10-hydroxy-9-phosphonooxy-octadecanoic acid homo sapiens 0.35 0.35 1 PMID:12574510 -3.3.2.10 trans-1,3-diphenylpropene oxide gallus gallus 0.9 0.9 1 PMID:16523628 -3.3.2.10 trans-1,3-diphenylpropene oxide homo sapiens 0.99 0.99 1 PMID:24771868 -3.3.2.10 trans-1,3-diphenylpropene oxide strongylocentrotus purpuratus 44.0 44.0 1 PMID:18554159 -3.3.2.10 trans-stilbene oxide arabidopsis thaliana 1.3 1.3 1 PMID:12356472 -3.3.2.10 trans-stilbene oxide brassica napus 0.3 0.3 1 PMID:12392563 -3.3.2.10 trans-stilbene oxide rattus norvegicus 0.5 0.5 1 PMID:12574508 -3.3.2.12 oxepin-coa escherichia coli 39.0 39.0 1 PMID:21296885 -3.3.2.13 chorismate actinoplanes sp. n902-109 0.117 0.117 1 PMID:30706936 -3.3.2.13 chorismate streptomyces hygroscopicus subsp. ascomyceticus 17.6 17.6 1 PMID:21383123 -3.3.2.15 (5s,6s)-6-amino-5-[(1-carboxyethenyl)oxy]cyclohexa-1,3-diene-1-carboxylate pseudomonas aeruginosa 7.3 7.3 1 PMID:12741825 -3.3.2.15 chorismate pseudomonas aeruginosa 1.2 1.2 1 PMID:12741825 -3.3.2.15 isochorismate pseudomonas aeruginosa 0.2 0.2 1 PMID:12741825 -3.3.2.2 choline lysoplasmalogen thermocrispum sp. rd004668 122.0 96.3 2 PMID:27833852;PMID:33599379 -3.3.2.2 lysoplasmenylcholine rattus norvegicus 10.3 10.3 1 PMID:21515882 -3.3.2.2 lysoplasmenylethanolamine rattus norvegicus 10.3 10.3 1 PMID:21515882 -3.3.2.4 d-trans-2,3-epoxysuccinate pseudomonas putida 83.3 83.3 1 PMID:5782001 -3.3.2.4 l-trans-2,3-epoxysuccinate pseudomonas putida 317.0 317.0 1 PMID:5782001 -3.3.2.6 alanine-4-nitroanilide homo sapiens 0.6 0.6 1 PMID:1536866 -3.3.2.6 arg-ser-arg homo sapiens 0.56 0.56 1 PMID:18804029 -3.3.2.6 l-ala-p-nitroanilide homo sapiens 1.7 1.7 1 PMID:18804029 -3.3.2.6 l-alanine 2-naphthylamide saccharomyces cerevisiae 0.03 0.03 1 PMID:20624488 -3.3.2.6 l-alanine-4-nitroanilide homo sapiens 1.9 1.9 1 PMID:18539590 -3.3.2.6 l-alanine-4-nitroanilide xenopus laevis 4.3 4.3 1 PMID:24333438 -3.3.2.6 l-arg-p-nitroanilide homo sapiens 1.9 1.9 1 PMID:18804029 -3.3.2.6 l-arginine 2-naphthylamide saccharomyces cerevisiae 0.02 0.02 1 PMID:20624488 -3.3.2.6 l-arginine-4-nitroanilide homo sapiens 0.15 0.15 1 PMID:1536866 -3.3.2.6 l-isoleucine 2-naphthylamide saccharomyces cerevisiae 0.01 0.01 1 PMID:20624488 -3.3.2.6 l-leucine 2-naphthylamide saccharomyces cerevisiae 0.15 0.15 1 PMID:20624488 -3.3.2.6 l-leucine-4-nitroanilide homo sapiens 0.35 0.25 2 PMID:10574934;PMID:1536866 -3.3.2.6 l-leucine-4-nitroanilide saccharomyces cerevisiae 5.2 2.915 2 PMID:10574934 -3.3.2.6 l-methionine 2-naphthylamide saccharomyces cerevisiae 0.15 0.15 1 PMID:20624488 -3.3.2.6 l-valine 2-naphthylamide saccharomyces cerevisiae 0.02 0.02 1 PMID:20624488 -3.3.2.6 leukotriene a4 homo sapiens 2.4 1.79 4 PMID:1536866;PMID:6490615;PMID:8650196;PMID:8798687;PMID:9744798 -3.3.2.6 leukotriene a4 mus musculus 0.9 0.8 2 PMID:7582974 -3.3.2.6 leukotriene a4 xenopus laevis 20.1 17.05 2 PMID:24333438;PMID:9744798 -3.3.2.6 lysine-4-nitroanilide homo sapiens 0.04 0.04 1 PMID:1536866 -3.3.2.6 proline-4-nitroanilide homo sapiens 0.15 0.15 1 PMID:1536866 -3.3.2.8 cis-2,3-butene oxide rhodococcus erythropolis 0.035 0.035 1 PMID:31961471 -3.3.2.8 cis-stilbene oxide rhodococcus erythropolis 0.147 0.147 1 PMID:31961471 -3.3.2.8 cyclohexene-1,2-epoxide rhodococcus erythropolis 0.82 0.82 1 * -3.3.2.8 cyclopentene oxide rhodococcus erythropolis 0.056 0.056 1 PMID:31961471 -3.3.2.8 styrene-7,8-oxide rhodococcus erythropolis 0.47 0.47 1 PMID:12773375 -3.3.2.9 1,10-phenanthroline 5,6-oxide rattus norvegicus 53.0 53.0 1 PMID:8383521 -3.3.2.9 13,14-epoxy-docosapentaenoic acid homo sapiens 0.37 0.37 1 PMID:34066758 -3.3.2.9 14,15-epoxyeicosatrienoic acid homo sapiens 0.044 0.044 1 PMID:34066758 -3.3.2.9 8,9-epoxyeicosatrienoic acid homo sapiens 0.032 0.032 1 PMID:34066758 -3.3.2.9 hepoxilin a3 homo sapiens 0.019 0.019 1 PMID:34066758 -3.3.2.9 juvenile hormone iii heliothis virescens 0.002 0.002 1 PMID:23276675 -3.3.2.9 juvenile hormone iii homalodisca vitripennis 0.03 0.03 1 PMID:23704009 -3.3.2.9 juvenile hormone iii manduca sexta 0.08 0.08 1 PMID:8396141 -3.3.2.9 phenanthrene 9,10-oxide rattus norvegicus 0.5 0.5 1 PMID:8383521 -3.4.11.1 ala-4-methylcoumaryl-7-amide plasmodium falciparum 0.0002 0.0002 1 PMID:17107951 -3.4.11.1 arg-gly solanum lycopersicum 13520.0 13510.0 2 PMID:10672029 -3.4.11.1 arg-gly-asp solanum lycopersicum 3781.0 3780.5 2 PMID:10672029 -3.4.11.1 arg-gly-phe solanum lycopersicum 6073.0 6071.5 2 PMID:10672029 -3.4.11.1 arg-leu solanum lycopersicum 19400.0 19390.0 2 PMID:10672029 -3.4.11.1 asp-gln salmonella enterica 761.0 761.0 1 PMID:10852868 -3.4.11.1 asp-his salmonella enterica 418.0 418.0 1 PMID:10852868 -3.4.11.1 asp-ile-gly-gly salmonella enterica 26.0 26.0 1 PMID:10852868 -3.4.11.1 asp-leu salmonella enterica 666.0 666.0 1 PMID:10852868 -3.4.11.1 asp-leu-gly salmonella enterica 950.0 950.0 1 PMID:10852868 -3.4.11.1 asp-leu-lys salmonella enterica 13.0 13.0 1 PMID:10852868 -3.4.11.1 asp-phe salmonella enterica 500.0 500.0 1 PMID:10852868 -3.4.11.1 asp-tyr salmonella enterica 500.0 500.0 1 PMID:10852868 -3.4.11.1 beta-cyclohexyl-l-alanyl-4-methylcoumaryl-7-amide plasmodium berghei 16.4 8.35 2 PMID:34133730 -3.4.11.1 beta-cyclohexyl-l-alanyl-4-methylcoumaryl-7-amide plasmodium falciparum 1.6 0.80022 2 PMID:34133730 -3.4.11.1 beta-cyclohexyl-l-alanyl-4-methylcoumaryl-7-amide plasmodium vivax 22.4 11.399999999999999 2 PMID:34133730 -3.4.11.1 cys-gly bos taurus 118.3 67.0 7 PMID:14583094 -3.4.11.1 glu-leu salmonella enterica 866.0 866.0 1 PMID:10852868 -3.4.11.1 gly-gly solanum lycopersicum 10900.0 10880.0 2 PMID:10672029 -3.4.11.1 gly-leu solanum lycopersicum 5141.0 5140.5 2 PMID:10672029 -3.4.11.1 gly-phe sus scrofa 0.5 0.5 1 * -3.4.11.1 glycine-4-methylcoumaryl-7-amide eisenia fetida 45.6 45.6 1 * -3.4.11.1 harg-7-amido-4-methylcoumarin staphylococcus aureus 0.1584 0.1584 1 PMID:23241672 -3.4.11.1 l-ala-4-nitroanilide clonorchis sinensis 0.12 0.12 2 PMID:22155540 -3.4.11.1 l-ala-4-nitroanilide thermotoga maritima 0.078 0.078 1 * -3.4.11.1 l-ala-7-amido-4-methylcoumarin leishmania amazonensis 2.94 2.275 2 * -3.4.11.1 l-ala-7-amido-4-methylcoumarin leishmania donovani 2.94 2.4749999999999996 2 * -3.4.11.1 l-ala-7-amido-4-methylcoumarin leishmania major 2.94 2.415 2 * -3.4.11.1 l-alanine-4-methylcoumarin-7-amide toxoplasma gondii 0.03 0.03 1 PMID:19931316 -3.4.11.1 l-alanine-4-methylcoumaryl-7-amide babesia gibsoni 8.2 8.2 1 PMID:19549347 -3.4.11.1 l-alanine-4-methylcoumaryl-7-amide cryptosporidium parvum 0.01 0.01 1 PMID:21414242 -3.4.11.1 l-alanine-4-methylcoumaryl-7-amide eisenia fetida 38.7 38.7 1 * -3.4.11.1 l-arg-7-amido-4-methylcoumarin staphylococcus aureus 0.1395 0.1395 1 PMID:23241672 -3.4.11.1 l-arginine-4-methylcoumarin-7-amide toxoplasma gondii 0.041 0.041 1 PMID:19931316 -3.4.11.1 l-arginine-4-methylcoumaryl-7-amide babesia gibsoni 37.79 37.79 1 PMID:19549347 -3.4.11.1 l-arginine-4-methylcoumaryl-7-amide eisenia fetida 12.1 12.1 1 * -3.4.11.1 l-arginyl-7-amido-4-methylcoumarin acanthamoeba castellanii 0.13 0.13 1 PMID:26075721 -3.4.11.1 l-arginyl-7-amido-4-methylcoumarin pagrus major 17.3 17.3 1 PMID:18800800 -3.4.11.1 l-cys-7-amido-4-methylcoumarin leishmania amazonensis 6.0 4.36 2 * -3.4.11.1 l-cys-7-amido-4-methylcoumarin leishmania donovani 6.0 4.67 2 * -3.4.11.1 l-cys-7-amido-4-methylcoumarin leishmania major 2.94 2.565 2 * -3.4.11.1 l-ile-4-nitroanilide clonorchis sinensis 0.01 0.01 1 PMID:22155540 -3.4.11.1 l-ile-7-amido-4-methylcoumarin leishmania amazonensis 0.19 0.19 1 * -3.4.11.1 l-ile-7-amido-4-methylcoumarin leishmania donovani 0.09 0.09 1 * -3.4.11.1 l-ile-7-amido-4-methylcoumarin leishmania major 0.19 0.19 1 * -3.4.11.1 l-leu-4-nitroanilide bos taurus 0.7 0.7 1 PMID:8982850 -3.4.11.1 l-leu-4-nitroanilide clonorchis sinensis 0.27 0.25 2 PMID:22155540 -3.4.11.1 l-leu-4-nitroanilide desulfurococcus amylolyticus 19.0 12.2 2 PMID:22419090 -3.4.11.1 l-leu-4-nitroanilide thermotoga maritima 0.285 0.15034999999999998 2 * -3.4.11.1 l-leu-7-amido-4-methylcoumarin leishmania amazonensis 0.41 0.41 1 * -3.4.11.1 l-leu-7-amido-4-methylcoumarin leishmania donovani 0.52 0.52 1 * -3.4.11.1 l-leu-7-amido-4-methylcoumarin leishmania major 0.65 0.65 1 * -3.4.11.1 l-leu-7-amido-4-methylcoumarin staphylococcus aureus 0.1204 0.1204 1 PMID:23241672 -3.4.11.1 l-leu-7-amido-4-methylcoumarin trypanosoma cruzi 34.84 23.655 2 PMID:21861921 -3.4.11.1 l-leu-gly solanum lycopersicum 120.0 120.0 1 PMID:11895433 -3.4.11.1 l-leucine-4-methylcoumarin-7-amide toxoplasma gondii 0.089 0.089 1 PMID:19931316 -3.4.11.1 l-leucine-4-methylcoumaryl-7-amide babesia gibsoni 198.8 198.8 1 PMID:19549347 -3.4.11.1 l-leucine-4-methylcoumaryl-7-amide cryptosporidium parvum 0.107 0.107 1 PMID:21414242 -3.4.11.1 l-leucine-4-methylcoumaryl-7-amide eisenia fetida 34.6 34.6 1 * -3.4.11.1 l-leucine-4-methylcoumaryl-7-amide plasmodium falciparum 0.0094 0.0094 1 PMID:19408962 -3.4.11.1 l-leucine-4-nitroanilide aspergillus oryzae 50.9 50.9 1 PMID:20803144 -3.4.11.1 l-leucyl-4-nitroanilide leishmania major 14.7 14.7 1 PMID:33775769 -3.4.11.1 l-leucyl-4-nitroanilide thermomyces lanuginosus 1165.79 1165.79 1 PMID:31759085 -3.4.11.1 l-leucyl-4-nitroanilide trypanosoma cruzi 4.4 4.4 1 PMID:30905022 -3.4.11.1 l-leucyl-7-amido-4-methylcoumarin acanthamoeba castellanii 0.83 0.83 1 PMID:26075721 -3.4.11.1 l-leucyl-7-amido-4-methylcoumarin pagrus major 26.4 26.4 1 PMID:18800800 -3.4.11.1 l-leucylamide sus scrofa 112.0 112.0 1 PMID:19428710 -3.4.11.1 l-lys-4-nitroanilide clonorchis sinensis 0.07 0.060000000000000005 2 PMID:22155540 -3.4.11.1 l-lys-4-nitroanilide thermotoga maritima 0.194 0.1022 2 * -3.4.11.1 l-lysine-4-methylcoumaryl-7-amide cryptosporidium parvum 0.002 0.002 1 PMID:21414242 -3.4.11.1 l-met-4-nitroanilide clonorchis sinensis 0.2 0.19 2 PMID:22155540 -3.4.11.1 l-met-7-amido-4-methylcoumarin leishmania amazonensis 4.99 4.145 2 * -3.4.11.1 l-met-7-amido-4-methylcoumarin leishmania donovani 5.08 4.1899999999999995 2 * -3.4.11.1 l-met-7-amido-4-methylcoumarin leishmania major 5.52 5.52 1 * -3.4.11.1 l-methionine-4-methylcoumaryl-7-amide cryptosporidium parvum 0.085 0.085 1 PMID:21414242 -3.4.11.1 l-methionyl-7-amido-4-methylcoumarin acanthamoeba castellanii 0.33 0.33 1 PMID:26075721 -3.4.11.1 l-phe-4-nitroanilide clonorchis sinensis 0.05 0.045 2 PMID:22155540 -3.4.11.1 l-phenylalanine-4-methylcoumarin-7-amide toxoplasma gondii 0.0002 0.0002 1 PMID:19931316 -3.4.11.1 l-phenylalanine-4-methylcoumaryl-7-amide babesia gibsoni 24.61 24.61 1 PMID:19549347 -3.4.11.1 l-phenylalanine-4-methylcoumaryl-7-amide cryptosporidium parvum 0.075 0.075 1 PMID:21414242 -3.4.11.1 l-phenylalanine-4-nitroanilide aspergillus oryzae 37.0 37.0 1 PMID:20803144 -3.4.11.1 l-pro-4-nitroanilide clonorchis sinensis 0.02 0.02 2 PMID:22155540 -3.4.11.1 l-pro-4-nitroanilide thermotoga maritima 0.021 0.021 1 * -3.4.11.1 l-proline-4-methylcoumarin-7-amide toxoplasma gondii 0.0016 0.0016 1 PMID:19931316 -3.4.11.1 l-proline-4-methylcoumaryl-7-amide babesia gibsoni 2.03 2.03 1 PMID:19549347 -3.4.11.1 l-proline-4-methylcoumaryl-7-amide eisenia fetida 1.3 1.3 1 * -3.4.11.1 l-thr-4-nitroanilide clonorchis sinensis 0.02 0.015 2 PMID:22155540 -3.4.11.1 l-trp-7-amido-4-methylcoumarin leishmania amazonensis 0.07 0.07 1 * -3.4.11.1 l-trp-7-amido-4-methylcoumarin leishmania donovani 0.21 0.21 1 * -3.4.11.1 l-trp-7-amido-4-methylcoumarin leishmania major 0.22 0.22 1 * -3.4.11.1 l-tyrosine-4-methylcoumaryl-7-amide eisenia fetida 13.8 13.8 1 * -3.4.11.1 l-val-4-nitroanilide clonorchis sinensis 0.01 0.01 1 PMID:22155540 -3.4.11.1 l-valine-4-methylcoumaryl-7-amide eisenia fetida 1.5 1.5 1 * -3.4.11.1 leu-4-methylcoumaryl-7-amide plasmodium falciparum 0.039 0.039 1 PMID:17107951 -3.4.11.1 leu-4-nitroanilide sus scrofa 0.04 0.021500000000000002 2 * -3.4.11.1 leu-gly bos taurus 675.0 296.0 4 PMID:14583094 -3.4.11.1 leu-gly solanum lycopersicum 14440.0 14400.0 3 PMID:10672029 -3.4.11.1 leu-gly sus scrofa 1670.0 1670.0 1 * -3.4.11.1 leu-gly-gly solanum lycopersicum 14000.0 13980.0 2 PMID:10672029 -3.4.11.1 leu-leu salmonella enterica 918.0 918.0 1 PMID:10852868 -3.4.11.1 leu-leu solanum lycopersicum 34500.0 34495.0 2 PMID:10672029 -3.4.11.1 leu-p-nitroanilide geobacillus kaustophilus 5.92 5.92 1 PMID:18848841 -3.4.11.1 leu-phe sus scrofa 270.0 270.0 1 * -3.4.11.1 leu-tyr salmonella enterica 351.0 351.0 1 PMID:10852868 -3.4.11.1 leucyl-4-methylcoumaryl-7-amide plasmodium berghei 2.27 1.345 2 PMID:34133730 -3.4.11.1 leucyl-4-methylcoumaryl-7-amide plasmodium falciparum 0.12 0.065 2 PMID:34133730 -3.4.11.1 leucyl-4-methylcoumaryl-7-amide plasmodium vivax 0.14 0.09000000000000001 2 PMID:34133730 -3.4.11.1 met-gly bos taurus 988.3 477.15 6 PMID:14583094 -3.4.11.1 phe-4-methylcoumaryl-7-amide plasmodium falciparum 0.00145 0.00145 1 PMID:17107951 -3.4.11.1 phg-7-amido-4-methylcoumarin staphylococcus aureus 0.3952 0.3952 1 PMID:23241672 -3.4.11.1 pro-4-methylcoumaryl-7-amide plasmodium falciparum 0.00059 0.00059 1 PMID:17107951 -3.4.11.1 ser-gly bos taurus 42.0 29.5 2 PMID:14583094 -3.4.11.10 arg-phe aeromonas caviae 6.0 6.0 1 * -3.4.11.10 cys-gly treponema denticola 60.0 46.7 3 PMID:18482986 -3.4.11.10 glu-phe aeromonas caviae 0.001 0.001 1 * -3.4.11.10 gly-7-amido-4-methylcoumarin escherichia coli 11.0 11.0 1 PMID:20350528 -3.4.11.10 ile-amide vibrio proteolyticus 6.2 6.2 1 PMID:5010066 -3.4.11.10 ile-phe aeromonas caviae 10.0 10.0 1 * -3.4.11.10 l-ala-4-nitroanilide bacillus subtilis 0.37 0.37 1 PMID:15668014 -3.4.11.10 l-ala-7-amido-4-methylcoumarin fasciola hepatica 192000.0 192000.0 1 PMID:18178266 -3.4.11.10 l-ala-l-ala-l-phe-7-amido-4-methylcoumarin escherichia coli 10.0 10.0 1 PMID:20350528 -3.4.11.10 l-arg-4-nitroanilide bacillus subtilis 34.0 34.0 1 PMID:15668014 -3.4.11.10 l-arg-7-amido-4-methylcoumarin fasciola hepatica 59900.0 59900.0 1 PMID:18178266 -3.4.11.10 l-arg-p-nitroanilide streptomyces septatus 1.26 1.26 1 PMID:17028223 -3.4.11.10 l-cys-7-amido-4-methylcoumarin fasciola hepatica 288100.0 288100.0 1 PMID:18178266 -3.4.11.10 l-cystinyl-p-nitroanilide streptomyces septatus 3.71 3.71 1 PMID:17028223 -3.4.11.10 l-leu-4-nitroanilide bacillus subtilis 55.0 55.0 1 PMID:15668014 -3.4.11.10 l-leu-4-nitroanilide geobacillus kaustophilus 6.31 6.31 1 PMID:15702388 -3.4.11.10 l-leu-4-nitroanilide geobacillus stearothermophilus 0.303 0.2965 2 PMID:15928987;PMID:18286359 -3.4.11.10 l-leu-4-nitroanilide geobacillus thermoleovorans 10180.0 10180.0 1 PMID:15937698 -3.4.11.10 l-leu-4-nitroanilide vibrio proteolyticus 73.0 48.45 7 PMID:15358350;PMID:16142900;PMID:18576673;PMID:24368112 -3.4.11.10 l-leu-7-amido-4-methylcoumarin escherichia coli 17.0 17.0 1 PMID:20350528 -3.4.11.10 l-leu-7-amido-4-methylcoumarin fasciola hepatica 246000.0 246000.0 1 PMID:18178266 -3.4.11.10 l-leu-gly-gly geobacillus thermoleovorans 49540.0 49540.0 1 PMID:15937698 -3.4.11.10 l-leu-p-nitroanilide streptomyces septatus 41.3 41.3 1 PMID:17028223 -3.4.11.10 l-leu-p-nitroanilide treponema denticola 41.7 35.85 2 PMID:18482986 -3.4.11.10 l-leucine 4-nitroanilide vibrio proteolyticus 4320.0 55.5 13 PMID:1012016;PMID:11401547;PMID:11888288;PMID:4441102;PMID:7056743;PMID:7173208 -3.4.11.10 l-leucine anilide vibrio proteolyticus 16.0 15.1 3 PMID:11888288 -3.4.11.10 l-leucine ethyl ester vibrio proteolyticus 96.0 96.0 1 PMID:11862549 -3.4.11.10 l-leucine-4-anisidide vibrio proteolyticus 9.5 9.3 3 PMID:11888288 -3.4.11.10 l-lys-4-nitroanilide bacillus subtilis 10.0 10.0 1 PMID:15668014 -3.4.11.10 l-lys-4-nitroanilide escherichia coli 17.7 17.7 1 PMID:20350528 -3.4.11.10 l-met-7-amido-4-methylcoumarin escherichia coli 20.0 20.0 1 PMID:20350528 -3.4.11.10 l-met-7-amido-4-methylcoumarin fasciola hepatica 283200.0 283200.0 1 PMID:18178266 -3.4.11.10 l-phe-7-amido-4-methylcoumarin fasciola hepatica 33800.0 33800.0 1 PMID:18178266 -3.4.11.10 l-thr-7-amido-4-methylcoumarin fasciola hepatica 16200.0 16200.0 1 PMID:18178266 -3.4.11.10 l-val-4-nitroanilide bacillus subtilis 0.43 0.43 1 PMID:15668014 -3.4.11.10 l-val-l-phe aeromonas caviae 1.3 1.3 1 * -3.4.11.10 leu-ala vibrio proteolyticus 15.0 15.0 1 PMID:1012016;PMID:5010066 -3.4.11.10 leu-amide vibrio proteolyticus 220.0 220.0 1 PMID:1012016;PMID:5010066 -3.4.11.10 leu-arg vibrio proteolyticus 39.0 39.0 1 PMID:1012016;PMID:5010066 -3.4.11.10 leu-beta-naphthylamide aeromonas caviae 38.0 38.0 1 * -3.4.11.10 leu-beta-naphthylamide vibrio proteolyticus 29.6 29.6 1 PMID:1012016;PMID:5010066 -3.4.11.10 leu-ile vibrio proteolyticus 16.0 16.0 1 PMID:1012016;PMID:5010066 -3.4.11.10 leu-leu vibrio proteolyticus 8.3 8.3 1 PMID:1012016;PMID:5010066 -3.4.11.10 leu-met vibrio proteolyticus 53.0 53.0 1 PMID:1012016;PMID:5010066 -3.4.11.10 leu-methyl ester vibrio proteolyticus 145.0 145.0 1 PMID:1012016 -3.4.11.10 leu-phe aeromonas caviae 41.0 41.0 1 * -3.4.11.10 leu-phe vibrio proteolyticus 72.0 72.0 1 PMID:1012016;PMID:5010066 -3.4.11.10 leu-trp vibrio proteolyticus 58.0 58.0 1 PMID:1012016;PMID:5010066 -3.4.11.10 leu-tyr vibrio proteolyticus 85.0 85.0 1 PMID:1012016;PMID:5010066 -3.4.11.10 leu-val vibrio proteolyticus 15.0 15.0 1 PMID:1012016;PMID:5010066 -3.4.11.10 met-amide vibrio proteolyticus 32.0 32.0 1 PMID:5010066 -3.4.11.10 met-beta-naphthylamide aeromonas caviae 8.2 8.2 1 * -3.4.11.10 met-phe aeromonas caviae 22.0 22.0 1 * -3.4.11.10 norleucinamide vibrio proteolyticus 60.0 60.0 1 PMID:1012016;PMID:5010066 -3.4.11.10 norvalinamide vibrio proteolyticus 67.0 67.0 1 PMID:5010066 -3.4.11.10 peptide vibrio proteolyticus 67.0 67.0 1 PMID:11862549 -3.4.11.10 phe-amide vibrio proteolyticus 6.2 6.2 1 PMID:5010066 -3.4.11.10 phe-beta-naphthylamide aeromonas caviae 6.3 6.3 1 * -3.4.11.10 phe-methyl ester vibrio proteolyticus 42.0 42.0 1 PMID:1012016 -3.4.11.10 phe-phe aeromonas caviae 158.0 158.0 1 * -3.4.11.10 recombinant human methionine-interferon alpha-2b vibrio proteolyticus 0.000853 0.000853 1 * -3.4.11.10 thionoleucine-4-anisidide vibrio proteolyticus 12.2 9.5 4 PMID:11888288 -3.4.11.10 thionoleucine-s-anilide vibrio proteolyticus 23.3 11.5 5 PMID:11888288 -3.4.11.10 val-amide vibrio proteolyticus 6.5 6.5 1 PMID:5010066 -3.4.11.10 val-beta-naphthylamide aeromonas caviae 0.26 0.26 1 * -3.4.11.13 ala-gly-gly hathewaya histolytica 1830.0 1830.0 1 PMID:13266;PMID:4318;PMID:4631895 -3.4.11.13 l-leucine 4-nitroanilide hathewaya histolytica 4.2 4.2 1 PMID:6477932 -3.4.11.13 leu-gly-gly hathewaya histolytica 917.0 917.0 1 PMID:13266;PMID:4318;PMID:4631895 -3.4.11.13 phe-gly-gly hathewaya histolytica 667.0 667.0 1 PMID:13266;PMID:4318;PMID:4631895 -3.4.11.13 pro-gly-gly hathewaya histolytica 1360.0 1360.0 1 PMID:13266;PMID:4318;PMID:4631895 -3.4.11.13 pro-gly-pro hathewaya histolytica 561.0 561.0 1 PMID:13266;PMID:4318;PMID:4631895 -3.4.11.13 pro-gly-pro-pro hathewaya histolytica 337.0 337.0 1 PMID:13266;PMID:4318;PMID:4631895 -3.4.11.13 val-gly-gly hathewaya histolytica 276.0 276.0 1 PMID:13266;PMID:4318;PMID:4631895 -3.4.11.14 ala-2-naphthylamide homo sapiens 141.0 141.0 1 PMID:698181 -3.4.11.14 ala-7-amido-4-methylcoumarin rattus norvegicus 13.1 13.1 1 PMID:9687021 -3.4.11.14 ala-p-nitroanilide homo sapiens 20.83 12.315 2 PMID:17154549 -3.4.11.14 arg-2-naphthylamide homo sapiens 22.2 22.2 1 PMID:698181 -3.4.11.14 arg-7-amido-4-methylcoumarin rattus norvegicus 0.13 0.13 1 PMID:9687021 -3.4.11.14 arg-arg-7-amido-4-methylcoumarin rattus norvegicus 0.11 0.11 1 PMID:9687021 -3.4.11.14 glycine-4-methylcoumaryl-7-amide danio rerio 10.3 10.3 1 PMID:21276865 -3.4.11.14 ile-2-naphthylamide homo sapiens 6.33 6.33 1 PMID:698181 -3.4.11.14 l-alanine-4-methylcoumaryl-7-amide danio rerio 48.9 48.9 1 PMID:21276865 -3.4.11.14 l-arginine-4-methylcoumaryl-7-amide danio rerio 3.8 3.8 1 PMID:21276865 -3.4.11.14 l-leucine-4-methylcoumaryl-7-amide danio rerio 8.2 8.2 1 PMID:21276865 -3.4.11.14 l-lysine-4-methylcoumaryl-7-amide danio rerio 17.1 17.1 1 PMID:21276865 -3.4.11.14 l-methionine-4-methylcoumaryl-7-amide danio rerio 25.6 25.6 1 PMID:21276865 -3.4.11.14 l-proline-4-methylcoumaryl-7-amide danio rerio 1.1 1.1 1 PMID:21276865 -3.4.11.14 l-tyrosine-4-methylcoumaryl-7-amide danio rerio 38.5 38.5 1 PMID:21276865 -3.4.11.14 l-valine-4-methylcoumaryl-7-amide danio rerio 0.9 0.9 1 PMID:21276865 -3.4.11.14 leu-2-naphthylamide homo sapiens 49.5 49.5 1 PMID:698181 -3.4.11.14 leu-7-amido-4-methylcoumarin rattus norvegicus 11.3 11.3 1 PMID:9687021 -3.4.11.14 leu-p-nitroanilide homo sapiens 19.83 11.665 2 PMID:17154549 -3.4.11.14 lys-2-naphthylamide homo sapiens 11.3 11.3 1 PMID:698181 -3.4.11.14 lys-7-amido-4-methylcoumarin rattus norvegicus 19.5 19.5 1 PMID:9687021 -3.4.11.14 lys-ala-7-amido-4-methylcoumarin rattus norvegicus 4.5 4.5 1 PMID:9687021 -3.4.11.14 lys-p-nitroanilide homo sapiens 89.0 89.0 1 PMID:17154549 -3.4.11.14 met-2-naphthylamide homo sapiens 95.5 95.5 1 PMID:698181 -3.4.11.14 met-7-amido-4-methylcoumarin rattus norvegicus 14.3 14.3 1 PMID:9687021 -3.4.11.14 met-p-nitroanilide homo sapiens 30.0 30.0 1 PMID:17154549 -3.4.11.14 phe-2-naphthylamide homo sapiens 74.5 74.5 1 PMID:698181 -3.4.11.14 phe-7-amido-4-methylcoumarin rattus norvegicus 12.8 12.8 1 PMID:9687021 -3.4.11.14 pro-7-amido-4-methylcoumarin rattus norvegicus 1.5 1.5 1 PMID:9687021 -3.4.11.14 pro-p-nitroanilide homo sapiens 23.17 20.035 2 PMID:17154549 -3.4.11.14 pro-phe-arg-7-amido-4-methylcoumarin rattus norvegicus 0.97 0.97 1 PMID:9687021 -3.4.11.14 tyr-7-amido-4-methylcoumarin rattus norvegicus 7.7 7.7 1 PMID:9687021 -3.4.11.14 val-2-naphthylamide homo sapiens 3.83 3.83 1 PMID:698181 -3.4.11.14 val-p-nitroanilide homo sapiens 1.43 1.43 1 PMID:17154549 -3.4.11.15 l-arginine 4-nitroanilide pyrococcus furiosus 769.0 769.0 1 PMID:15743956 -3.4.11.15 l-lysine 4-nitroanilide pyrococcus furiosus 1840.0 1550.0 2 PMID:15743956 -3.4.11.15 lys-gly-gly pyrococcus furiosus 1460.0 882.5 2 PMID:15743956 -3.4.11.16 ala-trp sus scrofa 38.5 38.5 1 PMID:2890346 -3.4.11.16 alpha-asp-phe sus scrofa 117.0 117.0 1 * -3.4.11.16 alpha-asp-phe-nh2 sus scrofa 230.0 230.0 1 * -3.4.11.16 aspartame sus scrofa 238.0 238.0 1 * -3.4.11.16 glu-trp sus scrofa 113.0 113.0 1 PMID:2890346 -3.4.11.16 gly-trp sus scrofa 127.0 127.0 1 PMID:2890346 -3.4.11.16 leu-trp sus scrofa 92.6 92.6 1 PMID:2890346 -3.4.11.16 pro-trp sus scrofa 29.6 29.6 1 PMID:2890346 -3.4.11.18 l-alanine-4-methylcoumarin-7-amide leishmania donovani 2.13 1.58 6 PMID:29680505 -3.4.11.18 l-leu-7-amido-4-methylcoumarin klebsiella pneumoniae 0.101 0.101 1 PMID:30763644 -3.4.11.18 l-leu-7-amido-4-methylcoumarin pyrococcus furiosus 0.91 0.91 1 PMID:36396098 -3.4.11.18 l-leu-7-amido-4-methylcoumarin vibrio coralliilyticus 0.1593 0.1593 1 PMID:30763644 -3.4.11.18 l-met 4-nitroanilide mycobacterium tuberculosis 10.58 0.08 5 PMID:22466806;PMID:27225936 -3.4.11.18 l-met 4-nitroanilide streptococcus pneumoniae 0.0055 0.0055 1 PMID:24124477 -3.4.11.18 l-met-7-amido-4-methylcoumarin helicobacter pylori 0.1985 0.1985 1 PMID:34329997 -3.4.11.18 l-met-7-amido-4-methylcoumarin klebsiella pneumoniae 0.6535 0.6535 1 PMID:30763644 -3.4.11.18 l-met-7-amido-4-methylcoumarin leishmania donovani 0.125 0.0772 5 PMID:31759728 -3.4.11.18 l-met-7-amido-4-methylcoumarin mycobacterium tuberculosis 2.95 2.95 1 PMID:30763644 -3.4.11.18 l-met-7-amido-4-methylcoumarin pyrococcus furiosus 1.55 1.55 1 PMID:36396098 -3.4.11.18 l-met-7-amido-4-methylcoumarin vibrio cholerae 2.05 2.05 1 PMID:33035924 -3.4.11.18 l-met-7-amido-4-methylcoumarin vibrio coralliilyticus 0.63 0.6293 2 PMID:30763644;PMID:33035924 -3.4.11.18 l-met-7-amido-4-methylcoumarin vibrio parahaemolyticus 3.07 3.07 1 PMID:33035924 -3.4.11.18 l-met-gly-l-met-l-met escherichia coli 18.3 18.3 4 PMID:18855426;PMID:18952013;PMID:19019076 -3.4.11.18 l-met-l-ala-l-ser escherichia coli 11.0 11.0 1 PMID:18952013 -3.4.11.18 l-met-l-pro-4-nitroanilide homo sapiens 0.11 0.11 1 PMID:16274222 -3.4.11.18 l-met-l-ser-l-ser-l-his-l-arg-l-trp-l-asp-l-trp escherichia coli 84.0 84.0 1 PMID:18952013 -3.4.11.18 l-met-p-nitroanilide escherichia coli 0.006 0.006 1 PMID:16844071 -3.4.11.18 l-met-p-nitroanilide pyrococcus furiosus 0.057 0.057 1 PMID:16844071 -3.4.11.18 l-met-psi[c(o)s]gly-l-phe escherichia coli 22.5 22.5 1 PMID:14976199 -3.4.11.18 l-met-psi[c(o)s]gly-l-phe homo sapiens 6.47 6.47 1 PMID:15196033 -3.4.11.18 l-met-psi[c(o)s]gly-l-phe saccharomyces cerevisiae 15.8 12.8 3 PMID:15210064 -3.4.11.18 l-methionine 4-nitroanilide enterococcus faecalis 0.0043 0.0043 1 * -3.4.11.18 l-methionine 4-nitroanilide homo sapiens 0.0483 0.0483 1 PMID:25699713 -3.4.11.18 l-methionine 4-nitroanilide streptococcus pneumoniae 0.005 0.005 1 PMID:25699713 -3.4.11.18 l-methionine-4-methylcoumarin-7-amide mycobacterium tuberculosis 0.36 0.0575 4 PMID:20363127 -3.4.11.18 l-methionyl-7-amido-4-methylcoumarin ixodes persulcatus 0.25 0.25 1 PMID:33002807 -3.4.11.18 met-4-methylcoumaryl-7-amide acinetobacter baumannii 0.000449 0.00021099999999999998 8 PMID:21524572 -3.4.11.18 met-4-nitroanilide homo sapiens 0.158 0.158 1 PMID:11524009 -3.4.11.18 met-7-amido-4-methylcoumarin escherichia coli 0.0114 0.0059 3 PMID:12849997 -3.4.11.18 met-7-amido-4-methylcoumarin homo sapiens 0.0633 0.0633 1 PMID:11524009 -3.4.11.18 met-ala-ala synechocystis sp. 22.07 20.02 3 PMID:12861438 -3.4.11.18 met-ala-met-lys-ser escherichia coli 3.9 3.9 1 PMID:16963780 -3.4.11.18 met-ala-ser homo sapiens 3.5 1.77585 2 PMID:11524009;PMID:12718546 -3.4.11.18 met-ala-ser mycobacterium tuberculosis 1516.0 47.05 4 PMID:19688379;PMID:21729287 -3.4.11.18 met-ala-ser saccharomyces cerevisiae 19.6 19.6 1 PMID:7862096 -3.4.11.18 met-ala-ser-trp saccharomyces cerevisiae 8.45 8.45 1 PMID:10075912 -3.4.11.18 met-gly-ala-gln-phe-ser-lys-thr homo sapiens 0.0683 0.0683 1 PMID:12718546 -3.4.11.18 met-gly-gly synechocystis sp. 21.87 19.87 3 PMID:12861438 -3.4.11.18 met-gly-met-met escherichia coli 39.0 28.0 5 PMID:10419973;PMID:12755633;PMID:16844071;PMID:16963780 -3.4.11.18 met-gly-met-met homo sapiens 2.83 2.83 1 PMID:11524009 -3.4.11.18 met-gly-met-met mycobacterium tuberculosis 39.4 11.5 3 PMID:19688379;PMID:21729287 -3.4.11.18 met-gly-met-met plasmodium falciparum 9.13 7.6000000000000005 2 PMID:27023914 -3.4.11.18 met-gly-met-met pyrococcus furiosus 188.0 188.0 1 PMID:16844071 -3.4.11.18 met-gly-met-met saccharomyces cerevisiae 23.6 23.6 1 PMID:7862096 -3.4.11.18 met-peptide plasmodium falciparum 0.232 0.232 1 PMID:16983082 -3.4.11.18 met-pro homo sapiens 0.13 0.13 1 PMID:11524009 -3.4.11.18 met-pro-4-nitroanilide staphylococcus aureus 11.9 2.67 3 PMID:12946343 -3.4.11.18 met-pro-p-nitroanilide escherichia coli 1.82 1.4 3 PMID:12755633;PMID:17929833 -3.4.11.18 met-pro-p-nitroanilide homo sapiens 0.0065 0.0065 1 PMID:17929833 -3.4.11.18 met-s-gly-phe escherichia coli 42.5 20.2 3 PMID:12849997 -3.4.11.18 met-ser homo sapiens 0.00617 0.00617 1 PMID:11524009 -3.4.11.18 met-thr homo sapiens 0.01 0.01 1 PMID:11524009 -3.4.11.18 met-val homo sapiens 0.0133 0.0133 1 PMID:11524009 -3.4.11.18 met-val-ser-his-arg-trp-asp-trp saccharomyces cerevisiae 5.33 5.33 1 PMID:10075912 -3.4.11.18 nle-4-nitroanilide homo sapiens 0.0733 0.0733 1 PMID:11524009 -3.4.11.19 d-ala 4-nitroanilide aspergillus oryzae 2550.0 2550.0 1 PMID:22005737 -3.4.11.19 d-ala-4-nitroanilide aspergillus oryzae 2550.0 2550.0 1 PMID:22005737 -3.4.11.19 d-ala-4-nitroanilide brucella anthropi 580.0 395.0 2 PMID:16131658 -3.4.11.19 gly 4-nitroanilide aspergillus oryzae 2783.0 2783.0 1 PMID:22005737 -3.4.11.19 gly-4-nitroanilide aspergillus oryzae 2783.0 2783.0 1 PMID:22005737 -3.4.11.19 l-ala 4-nitroanilide aspergillus oryzae 2100.0 2100.0 1 PMID:22005737 -3.4.11.19 l-ala-4-nitroanilide aspergillus oryzae 2100.0 2100.0 1 PMID:22005737 -3.4.11.2 3-oh-l-pro-2-nai-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 1.19 1.19 1 PMID:23131591 -3.4.11.2 4-cl-l-phe-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 5.05 5.05 1 PMID:23131591 -3.4.11.2 6-obzl-l-nle-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 3.24 3.24 1 PMID:23131591 -3.4.11.2 ala-2-naphthylamide homo sapiens 303.0 303.0 1 PMID:6149934 -3.4.11.2 ala-4-methylcoumaryl-7-amide plasmodium falciparum 0.9 0.65 2 PMID:33536500 -3.4.11.2 alanyl-4-methylcoumaryl-7-amide plasmodium falciparum 0.9 0.65 2 PMID:33536500 -3.4.11.2 arg-4-methylcoumaryl-7-amide plasmodium falciparum 0.7 0.55 2 PMID:33536500 -3.4.11.2 arginyl-4-methylcoumaryl-7-amide plasmodium falciparum 0.7 0.55 2 PMID:33536500 -3.4.11.2 cys-gly arabidopsis thaliana 12.6 12.6 1 PMID:38441834 -3.4.11.2 gly-4-nitroanilide cucumis sativus 45.2 45.2 1 PMID:11826983 -3.4.11.2 gly-7-amido-4-methylcoumarin escherichia coli 92.0 92.0 1 PMID:20350528 -3.4.11.2 l-2-amino-3-(2-benzothiazolyl)butyric acid-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 13.8 13.8 1 PMID:23131591 -3.4.11.2 l-2-nai-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 2.6 2.6 1 PMID:23131591 -3.4.11.2 l-abu(bth)-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 5.25 5.25 1 PMID:23131591 -3.4.11.2 l-ala-2-naphthylamide cucumis sativus 149.0 149.0 1 PMID:11826983 -3.4.11.2 l-ala-2-naphthylamide novosphingobium capsulatum 860.0 860.0 1 PMID:11359790 -3.4.11.2 l-ala-4-nitroanilide cucumis sativus 34.3 34.3 1 PMID:11826983 -3.4.11.2 l-ala-4-nitroanilide escherichia coli 354.0 354.0 1 PMID:16380266 -3.4.11.2 l-ala-4-nitroanilide mizuhopecten yessoensis 29.5 29.5 1 * -3.4.11.2 l-ala-4-nitroanilide novosphingobium capsulatum 7600.0 7600.0 1 PMID:11359790 -3.4.11.2 l-ala-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 28.4 28.4 1 PMID:23131591 -3.4.11.2 l-ala-7-amido-4-methylcoumarin mizuhopecten yessoensis 9.49 5.73 2 * -3.4.11.2 l-ala-l-ala-l-phe-7-amido-4-methylcoumarin escherichia coli 53.0 53.0 1 PMID:20350528 -3.4.11.2 l-allyl-gly-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 4.9 4.9 1 PMID:23131591 -3.4.11.2 l-arg(no2)-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 7.25 7.25 1 PMID:23131591 -3.4.11.2 l-arg-2-naphthylamide cucumis sativus 19.3 19.3 1 PMID:11826983 -3.4.11.2 l-arg-4-nitroanilide escherichia coli 158.0 158.0 1 PMID:16380266 -3.4.11.2 l-arg-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 13.1 13.1 1 PMID:23131591 -3.4.11.2 l-asp(bzl)-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 3.64 3.64 1 PMID:23131591 -3.4.11.2 l-cha-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 3.84 3.84 1 PMID:23131591 -3.4.11.2 l-glu(bzl)-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 5.6 5.6 1 PMID:23131591 -3.4.11.2 l-harg-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 8.63 8.63 1 PMID:23131591 -3.4.11.2 l-hcha-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 3.19 3.19 1 PMID:23131591 -3.4.11.2 l-hleu-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 2.65 2.65 1 PMID:23131591 -3.4.11.2 l-hphe-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 13.0 13.0 1 PMID:23131591 -3.4.11.2 l-hser(bzl)-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 4.16 4.16 1 PMID:23131591 -3.4.11.2 l-hser-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 6.23 6.23 1 PMID:23131591 -3.4.11.2 l-htyr-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 12.7 12.7 1 PMID:23131591 -3.4.11.2 l-igl-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 1.72 1.72 1 PMID:23131591 -3.4.11.2 l-leu-4-nitroanilide cucumis sativus 6.7 6.7 1 PMID:11826983 -3.4.11.2 l-leu-4-nitroanilide escherichia coli 4.4 4.4 1 PMID:16380266 -3.4.11.2 l-leu-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 3.45 3.45 1 PMID:23131591 -3.4.11.2 l-leu-7-amido-4-methylcoumarin escherichia coli 90.0 90.0 1 PMID:20350528 -3.4.11.2 l-lys-2-naphthylamide cucumis sativus 23.1 23.1 1 PMID:11826983 -3.4.11.2 l-lys-4-nitroanilide escherichia coli 290.0 290.0 1 PMID:20350528 -3.4.11.2 l-lys-4-nitroanilide streptomyces sp. 21.3 20.0 2 PMID:17082929 -3.4.11.2 l-lys-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 6.15 6.15 1 PMID:23131591 -3.4.11.2 l-met-4-nitroanilide cucumis sativus 9.72 5.91 2 PMID:11826983 -3.4.11.2 l-met-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 5.99 5.99 1 PMID:23131591 -3.4.11.2 l-met-7-amido-4-methylcoumarin escherichia coli 80.0 80.0 1 PMID:20350528 -3.4.11.2 l-neopentyl-gly-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 1.64 1.64 1 PMID:23131591 -3.4.11.2 l-nle-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 2.72 2.72 1 PMID:23131591 -3.4.11.2 l-nva-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 3.33 3.33 1 PMID:23131591 -3.4.11.2 l-propargyl-gly-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 7.74 7.74 1 PMID:23131591 -3.4.11.2 l-ser-2-naphthylamide cucumis sativus 87.0 87.0 1 PMID:11826983 -3.4.11.2 l-tyr-7-amido-4-carbamoylmethylcoumarin neisseria meningitidis 1.66 1.66 1 PMID:23131591 -3.4.11.2 leu-4-methylcoumaryl-7-amide plasmodium falciparum 0.8 0.75 2 PMID:33536500 -3.4.11.2 leu-p-nitroanilide sus scrofa 174.0 174.0 1 PMID:5938934 -3.4.11.2 leu5-enkephalin sus scrofa 33.2 33.2 1 PMID:9425092 -3.4.11.2 leucyl-4-methylcoumaryl-7-amide plasmodium falciparum 0.8 0.75 2 PMID:33536500 -3.4.11.2 lvvypwtqrf sus scrofa 2.33 2.33 1 PMID:18236385 -3.4.11.2 vvypwtqrf sus scrofa 1.0 1.0 1 PMID:18236385 -3.4.11.2 vypwtqrf sus scrofa 1.0 1.0 1 PMID:18236385 -3.4.11.20 (s)-2-amino-4-cyclohexylbutanoyl-7-amido-4-methylcoumarin eimeria tenella 0.737 0.737 1 PMID:24839124 -3.4.11.20 ala-7-amido-4-methylcoumarin eimeria tenella 0.456 0.456 1 PMID:24839124 -3.4.11.20 arg-ala plasmodium falciparum 15.0 12.25 2 PMID:22348949 -3.4.11.20 his-ala plasmodium falciparum 2.4 1.7 2 PMID:22348949 -3.4.11.20 homoargininyl-7-amido-4-methylcoumarin eimeria tenella 0.575 0.575 1 PMID:24839124 -3.4.11.20 homophenylalanyl-7-amido-4-methylcoumarin eimeria tenella 0.836 0.836 1 PMID:24839124 -3.4.11.20 l-ala 4-nitroanilide plasmodium falciparum 1.15 1.15 1 PMID:25123643 -3.4.11.20 l-alanyl-2-naphthylamide plasmodium falciparum 16.0 11.0 2 PMID:21659511 -3.4.11.20 l-arg 4-nitroanilide plasmodium falciparum 1.58 1.58 1 PMID:25123643 -3.4.11.20 l-arginyl-2-naphthylamide plasmodium falciparum 21.0 10.2 4 PMID:21659511 -3.4.11.20 l-leu 4-nitroanilide plasmodium falciparum 1.65 1.65 1 PMID:25123643 -3.4.11.20 l-lys 4-nitroanilide plasmodium falciparum 1.55 1.55 1 PMID:25123643 -3.4.11.20 l-methionyl-7-amido-4-methylcoumarin eimeria tenella 0.704 0.704 1 PMID:24839124 -3.4.11.20 leu-ala plasmodium falciparum 12.0 10.65 2 PMID:22348949 -3.4.11.20 leu-gly plasmodium falciparum 6.5 6.5 1 PMID:22348949 -3.4.11.20 leu-gly-gly plasmodium falciparum 21.0 21.0 1 PMID:22348949 -3.4.11.20 leu-gly-leu plasmodium falciparum 4.8 4.8 1 PMID:22348949 -3.4.11.20 leu-gly-nh2 plasmodium falciparum 21.0 21.0 1 PMID:22348949 -3.4.11.20 leu-gly-pro plasmodium falciparum 12.0 12.0 1 PMID:22348949 -3.4.11.20 leu-leu plasmodium falciparum 12.0 7.9 3 PMID:21659511 -3.4.11.20 leu-nh2 plasmodium falciparum 12.0 12.0 1 PMID:22348949 -3.4.11.20 leu-pro-leu-arg-phenh2 gallus gallus 0.1 0.1 1 PMID:7684960 -3.4.11.20 lys-ala plasmodium falciparum 27.0 27.0 2 PMID:22348949 -3.4.11.20 met-phe plasmodium falciparum 7.5 7.4 3 PMID:21659511 -3.4.11.20 norleucyl-7-amido-4-methylcoumarin eimeria tenella 0.71 0.71 1 PMID:24839124 -3.4.11.20 norvalinyl-7-amido-4-methylcoumarin eimeria tenella 0.658 0.658 1 PMID:24839124 -3.4.11.20 styryl-ala-7-amido-4-methylcoumarin eimeria tenella 0.577 0.577 1 PMID:24839124 -3.4.11.21 asp-7-amido-4-methylcoumarin plasmodium falciparum 0.354 0.20199999999999999 2 PMID:17720817 -3.4.11.21 glu-7-amido-4-methylcoumarin plasmodium falciparum 0.33 0.1705 2 PMID:17720817 -3.4.11.22 ala-4-nitroanilide aspergillus oryzae 6.08 3.38 2 PMID:10899618 -3.4.11.22 ala-4-nitroanilide novosphingobium capsulatum 138.0 132.35 2 PMID:11359790 -3.4.11.22 ala-ala-pro-tyr-lys-amide aspergillus oryzae 4.34 3.735 2 PMID:10899618 -3.4.11.22 ala-beta-naphthylamide novosphingobium capsulatum 0.52 0.52 1 PMID:11359790 -3.4.11.22 ala-thr-ala saccharomyces cerevisiae 33300.0 33300.0 1 PMID:5147 -3.4.11.22 glu-4-nitroanilide aspergillus oryzae 0.13 0.13 1 PMID:10899618 -3.4.11.22 glu-ala-pro-tyr-lys-amide aspergillus oryzae 6.08 3.4 2 PMID:10899618 -3.4.11.22 gly-ala-pro-tyr-lys-amide aspergillus oryzae 6.08 3.48 2 PMID:10899618 -3.4.11.22 ile-4-nitroanilide aspergillus oryzae 0.18 0.18 1 PMID:10899618 -3.4.11.22 l-ala-ala-pro-leu-4-nitroanilide colwellia psychrerythraea 0.36 0.13 3 PMID:15184127 -3.4.11.22 l-leu-4-nitroanilide grifola frondosa 1.43 1.43 1 PMID:11302180 -3.4.11.22 l-leucine 4-nitroanilide vibrio proteolyticus 60.0 5.3 3 PMID:11888288 -3.4.11.22 l-leucine-4-anisidide vibrio proteolyticus 9.5 9.3 3 PMID:11888288 -3.4.11.22 l-leucine-anilide vibrio proteolyticus 16.0 15.1 3 PMID:11888288 -3.4.11.22 l-phe-4-nitroanilide grifola frondosa 0.95 0.95 1 PMID:11302180 -3.4.11.22 l-pro-4-nitroanilide aspergillus oryzae 0.08 0.08 1 PMID:10899618 -3.4.11.22 l-val-4-nitroanilide grifola frondosa 0.02 0.02 1 PMID:11302180 -3.4.11.22 leu-4-nitroanilide aspergillus oryzae 3.5 3.5 1 PMID:10899618 -3.4.11.22 leu-ala-pro-tyr-lys-amide aspergillus oryzae 3.67 3.4 2 PMID:10899618 -3.4.11.22 lys-4-nitroanilide aspergillus oryzae 1.8 1.8 1 PMID:10899618 -3.4.11.22 pro-ala-pro-tyr-lys-amide aspergillus oryzae 6.17 6.17 1 PMID:10899618 -3.4.11.22 thionoleucine-4-anisidide vibrio proteolyticus 12.2 9.5 4 PMID:11888288 -3.4.11.22 thionoleucine-s-anilide vibrio proteolyticus 23.3 11.5 5 PMID:11888288 -3.4.11.22 val-4-nitroanilide aspergillus oryzae 0.1 0.1 1 PMID:10899618 -3.4.11.23 asp-leu-gly salmonella enterica subsp. enterica serovar typhimurium 950.0 950.0 1 PMID:10852868 -3.4.11.23 glu-leu salmonella enterica subsp. enterica serovar typhimurium 866.0 866.0 1 PMID:10852868 -3.4.11.23 leu-leu salmonella enterica subsp. enterica serovar typhimurium 918.0 918.0 1 PMID:10852868 -3.4.11.24 4-nitrophenyl phenylphosphonate streptomyces sp. 0.022 0.014 5 * -3.4.11.24 ala-4-nitroanilide streptomyces griseus 4.9 4.9 1 PMID:17105197 -3.4.11.24 bis(4-nitrophenyl) phosphate streptomyces griseus 0.74 0.081 9 PMID:19879003 -3.4.11.24 bis(4-nitrophenyl) phosphate streptomyces sp. 0.74 0.21 5 * -3.4.11.24 bis(p-nitrophenyl)phosphate streptomyces griseus 0.42 0.42 1 PMID:17105197 -3.4.11.24 gly-4-nitroanilide streptomyces griseus 1.1 1.1 1 PMID:17105197 -3.4.11.24 l-ala-4-nitroanilide streptomyces griseus 2.94 2.325 2 PMID:8444149 -3.4.11.24 l-alanine-4-nitroanilide streptomyces griseus 2.94 1.81 3 PMID:9874195 -3.4.11.24 l-leu-4-nitroanilide streptomyces griseus 391.0 75.3 5 PMID:15063790;PMID:16407307;PMID:8444149 -3.4.11.24 l-leu-4-nitroanilide streptomyces septatus 65.9 42.1 3 PMID:15063790;PMID:16269763 -3.4.11.24 l-leu-nh2 streptomyces septatus 104.0 104.0 1 PMID:16269763 -3.4.11.24 l-leu-o-methyl ester streptomyces septatus 142.0 103.1 2 PMID:16269763 -3.4.11.24 l-leucine-4-nitroanilide streptomyces griseus 153.0 111.0 5 PMID:805135;PMID:9874195 -3.4.11.24 l-phe-4-nitroanilide streptomyces septatus 17.6 17.6 1 PMID:16269763 -3.4.11.24 l-phe-nh2 streptomyces septatus 43.8 43.8 1 PMID:16269763 -3.4.11.24 l-phe-o-methyl ester streptomyces septatus 54.3 27.47 2 PMID:16269763 -3.4.11.24 l-val-4-nitroanilide streptomyces griseus 0.191 0.191 1 PMID:8444149 -3.4.11.24 l-valine-4-nitroanilide streptomyces griseus 0.26 0.195 2 PMID:9874195 -3.4.11.24 leu-4-nitroanilide streptomyces griseus 657.0 32.45 10 PMID:17105197;PMID:19879003 -3.4.11.24 lys-4-nitroanilide streptomyces griseus 2.8 2.8 1 PMID:17105197 -3.4.11.24 met-4-nitroanilide streptomyces griseus 43.3 43.3 1 PMID:17105197 -3.4.11.24 val-4-nitroanilide streptomyces griseus 0.28 0.28 1 PMID:17105197 -3.4.11.25 beta-ala-p-nitroanilide sphingosinicella microcystinivorans 0.13 0.13 1 PMID:17064315;PMID:17193247 -3.4.11.25 beta-ala-p-nitroanilide sphingosinicella xenopeptidilytica 0.75 0.75 1 PMID:17064315;PMID:17193247 -3.4.11.25 beta-homoala-beta-homoleu sphingosinicella microcystinivorans 60.0 60.0 1 PMID:17064315 -3.4.11.25 beta-homoala-beta-homoleu sphingosinicella xenopeptidilytica 12.0 12.0 1 PMID:17064315 -3.4.11.25 beta-homoala-p-nitroanilide sphingosinicella microcystinivorans 2.89 2.89 1 PMID:17193247 -3.4.11.25 beta-homoala-p-nitroanilide sphingosinicella xenopeptidilytica 13.2 13.2 1 PMID:17193247 -3.4.11.25 beta-homogly 4-nitroanilide pseudomonas aeruginosa 1410.0 1250.0 2 PMID:23728237 -3.4.11.25 beta-homophe-p-nitroanilide sphingosinicella microcystinivorans 0.22 0.22 1 PMID:17193247 -3.4.11.25 beta-homophe-p-nitroanilide sphingosinicella xenopeptidilytica 30.2 30.2 1 PMID:17193247 -3.4.11.25 beta-homoval-beta-homoala-beta-homoleu sphingosinicella microcystinivorans 4.3 4.3 1 PMID:17064315 -3.4.11.25 beta-homoval-beta-homoala-beta-homoleu sphingosinicella xenopeptidilytica 6.0 6.0 1 PMID:17064315 -3.4.11.26 met-pro-ala saccharomyces cerevisiae 25.7 25.7 2 PMID:30582634 -3.4.11.26 tyr-ala-ala saccharomyces cerevisiae 1.4 1.4 2 PMID:30582634 -3.4.11.26 tyr-pro-ala saccharomyces cerevisiae 14.0 14.0 2 PMID:30582634 -3.4.11.27 l-ala-l-ala-l-phe-l-arg-7-amido-4-methylcoumarin pyrococcus horikoshii 0.0018 0.0018 1 PMID:25192005 -3.4.11.27 l-arg-7-amido-4-methylcoumarin pyrococcus horikoshii 0.0108 0.0108 1 PMID:25192005 -3.4.11.3 leu-4-methylcoumaryl-7-amide homo sapiens 9.18 5.575 2 PMID:10601849 -3.4.11.3 s-benzyl-cys-4-methylcoumaryl-7-amide homo sapiens 12.4 12.4 1 PMID:10601849 -3.4.11.4 ala-ala-phe-7-amido-4-methylcoumarin homo sapiens 41.66 22.439999999999998 2 PMID:15733845 -3.4.11.4 ala-phe-pro-beta-naphthylamide porphyromonas gingivalis 511.0 511.0 1 PMID:18042490 -3.4.11.4 arg-ala-arg homo sapiens 5.3 5.3 1 PMID:17357161 -3.4.11.4 arg-ser-arg homo sapiens 0.56 0.56 1 PMID:17357161 -3.4.11.4 gly-7-amido-4-methylcoumarin escherichia coli 12.0 12.0 1 PMID:20350528 -3.4.11.4 gly-ala-pro-beta-naphthylamide porphyromonas gingivalis 354.0 354.0 1 PMID:18042490 -3.4.11.4 gly-ala-pro-beta-naphthylamide serratia marcescens 354.0 354.0 1 PMID:16914159 -3.4.11.4 gly-gly-gly sus scrofa 2030.0 2030.0 1 PMID:4694732 -3.4.11.4 l-ala-l-ala-l-phe-7-amido-4-methylcoumarin escherichia coli 14.4 14.4 1 PMID:20350528 -3.4.11.4 l-alanine-4-nitroanilide homo sapiens 32.49 20.28 6 PMID:31751136 -3.4.11.4 l-asp-7-amido-4-methylcoumarin escherichia coli 11.7 11.7 1 PMID:20350528 -3.4.11.4 l-leu-7-amido-4-methylcoumarin escherichia coli 19.0 19.0 1 PMID:20350528 -3.4.11.4 l-lys-4-nitroanilide escherichia coli 14.3 14.3 1 PMID:20350528 -3.4.11.4 l-met-7-amido-4-methylcoumarin escherichia coli 14.0 14.0 1 PMID:20350528 -3.4.11.5 4-acetyloxyproline-2-naphthylamide serratia marcescens 84.1 84.1 1 PMID:16452443 -3.4.11.5 ala-p-nitroanilide grifola frondosa 8.0 8.0 1 PMID:15215614 -3.4.11.5 ala-para-nitroanilide aneurinibacillus sp. 81.1 81.1 1 PMID:15012820 -3.4.11.5 gly-p-nitroanilide grifola frondosa 7.8 7.8 1 PMID:15215614 -3.4.11.5 his-p-nitroanilide grifola frondosa 6.5 6.5 1 PMID:15215614 -3.4.11.5 l-hydroxyproline-2-naphthylamide serratia marcescens 3.9 3.9 1 PMID:16452443 -3.4.11.5 l-pro-4-nitroanilide aspergillus oryzae 15.34 15.34 1 PMID:32125650 -3.4.11.5 l-pro-4-nitroanilide phanerodontia chrysosporium 218.0 218.0 1 PMID:20188787 -3.4.11.5 l-pro-l-ala serratia marcescens 16.8 16.8 1 PMID:11011150 -3.4.11.5 l-proline-7-amido-4-methylcoumarin rasamsonia emersonii 213.7 213.7 1 PMID:19556294 -3.4.11.5 leu-para-nitroanilide aneurinibacillus sp. 340.0 340.0 1 PMID:15012820 -3.4.11.5 lys-para-nitroanilide aneurinibacillus sp. 26.2 26.2 1 PMID:15012820 -3.4.11.5 pro-2-naphthylamide serratia marcescens 9.7 9.7 1 PMID:16452443 -3.4.11.5 pro-beta-naphthylamide phanerodontia chrysosporium 64.55 64.55 1 PMID:25957260 -3.4.11.5 pro-p-nitroanilide grifola frondosa 160.0 160.0 1 PMID:15215614 -3.4.11.5 pro-para-nitroanilide aneurinibacillus sp. 26.0 26.0 1 PMID:15012820 -3.4.11.5 proline beta-naphthylamide serratia marcescens 9.81 5.955 2 PMID:11011150 -3.4.11.5 val-para-nitroanilide aneurinibacillus sp. 12.3 12.3 1 PMID:15012820 -3.4.11.6 arg 4-methylcoumarin 7-amide homo sapiens 9.27 9.27 1 PMID:24412328 -3.4.11.6 arg-4-methylcoumaryl-7-amide homo sapiens 2.3 2.3 1 PMID:12799365 -3.4.11.6 arg-7-amido-4-methylcoumarin homo sapiens 9.55 9.55 1 PMID:32236862 -3.4.11.6 arg-beta-naphthylamide rattus norvegicus 69.5 61.3 2 PMID:17142967 -3.4.11.6 arg-met-enkephalin homo sapiens 3.63 3.63 1 PMID:24412328 -3.4.11.6 cys-gly escherichia coli 10700.0 10700.0 1 PMID:11515538 -3.4.11.6 kallidin homo sapiens 2.35 2.35 1 PMID:24412328 -3.4.11.6 l-ala-4-nitroanilide bacillus subtilis 0.37 0.37 1 PMID:15668014 -3.4.11.6 l-ala-ala-pro-leu-4-nitroanilide colwellia psychrerythraea 0.36 0.13 3 PMID:15184127 -3.4.11.6 l-arg-2-naphthylamide rattus norvegicus 69.47 53.1 5 PMID:16981702;PMID:17142967;PMID:17974014;PMID:25530263 -3.4.11.6 l-arg-4-nitroanilide bacillus subtilis 34.0 34.0 1 PMID:15668014 -3.4.11.6 l-arg-7-amido-4-methylcoumarin homo sapiens 9.64 9.64 1 PMID:26352190 -3.4.11.6 l-arg-7-amido-4-methylcoumarin rattus norvegicus 43.0 43.0 1 PMID:30928100 -3.4.11.6 l-leu-4-nitroanilide bacillus subtilis 55.0 55.0 1 PMID:15668014 -3.4.11.6 l-lys-2-naphthylamide rattus norvegicus 23.6 13.3 2 PMID:16981702;PMID:17974014 -3.4.11.6 l-lys-4-nitroanilide bacillus subtilis 10.0 10.0 1 PMID:15668014 -3.4.11.6 l-lys-7-amido-4-methylcoumarin homo sapiens 12.9 12.9 1 PMID:26352190 -3.4.11.6 l-tyr-2-naphthylamide rattus norvegicus 2.1 2.1 1 PMID:16981702 -3.4.11.6 l-val-4-nitroanilide bacillus subtilis 0.43 0.43 1 PMID:15668014 -3.4.11.6 leu-4-nitroanilide escherichia coli 307.0 307.0 1 PMID:11515538 -3.4.11.6 leu-gly escherichia coli 6630.0 6630.0 1 PMID:11515538 -3.4.11.6 lys 4-methylcoumarin 7-amide homo sapiens 14.9 14.9 1 PMID:24412328 -3.4.11.6 met-enkephalin homo sapiens 0.47 0.47 1 PMID:24412328 -3.4.11.7 alpha-l-asp-2-naphthylamide mus musculus 102.0 102.0 1 PMID:11724556 -3.4.11.7 alpha-l-glu-2-naphthylamide mus musculus 404.0 404.0 1 PMID:11724556 -3.4.11.7 alpha-l-glu-beta-naphthylamide mus musculus 270.0 157.5 4 PMID:10715127;PMID:14674752 -3.4.11.7 alpha-l-glutamyl-beta-naphthylamide mus musculus 81.7 47.800000000000004 2 PMID:28877217 -3.4.11.7 angiotensin ii homo sapiens 6.0 3.01 3 PMID:17932029 -3.4.11.7 angiotensin ii mus musculus 20.0 20.0 1 PMID:11724556 -3.4.11.7 asp-4-methylcoumaryl-7-amide homo sapiens 12.2 7.5 2 PMID:16790432 -3.4.11.7 asp-7-amido-4-methylcoumarin plasmodium falciparum 0.354 0.20199999999999999 2 PMID:17720817 -3.4.11.7 cholecystokinin-8 homo sapiens 9.18 8.22 3 PMID:17932029 -3.4.11.7 gln-4-methylcoumaryl-7-amide homo sapiens 14.1 11.8 2 PMID:16790432 -3.4.11.7 glu-4-methylcoumaryl-7-amide homo sapiens 33.3 23.299999999999997 2 PMID:16790432 -3.4.11.7 glu-7-amido-4-methylcoumarin homo sapiens 5.25 4.33 2 PMID:17932029 -3.4.11.7 glu-7-amido-4-methylcoumarin plasmodium falciparum 0.33 0.1705 2 PMID:17720817 -3.4.11.7 glu-p-nitroanilide tetragenococcus halophilus 0.0025 0.0025 1 PMID:36597589 -3.4.11.7 kallidin homo sapiens 0.79 0.745 2 PMID:17932029 -3.4.11.7 l-glu-2-naphthylamide mus musculus 292.0 274.0 2 PMID:19228697 -3.4.11.7 l-glu-p-nitroanilide mus musculus 720.0 507.5 2 PMID:18598240 -3.4.11.7 l-leu-4-nitroanilide aspergillus oryzae 76.53 76.53 1 PMID:33989771 -3.4.11.7 neurokinin b homo sapiens 8.87 8.34 2 PMID:17932029 -3.4.11.9 (4-nitro)phe-pro-hn-ch2-ch2-nh-o-aminobenzoyl escherichia coli 135.0 135.0 1 PMID:6749499 -3.4.11.9 (4-nitro)phe-pro-pro-hn-ch2-ch2-nh-o-aminobenzoyl escherichia coli 20.0 20.0 1 PMID:6749499 -3.4.11.9 abz-l-lys-l-pro-l-pro-4-nitroanilide escherichia coli 95.0 95.0 1 PMID:16411772 -3.4.11.9 arg-pro rattus norvegicus 73.0 73.0 1 PMID:1645659 -3.4.11.9 arg-pro-ala deinococcus radiodurans 240.0 240.0 1 PMID:30536999 -3.4.11.9 arg-pro-pro bos taurus 120.0 120.0 1 PMID:1537867 -3.4.11.9 arg-pro-pro rattus norvegicus 230.0 165.0 4 PMID:1645659;PMID:7669781 -3.4.11.9 arg-pro-pro-benzylamide cavia porcellus 125.0 125.0 1 PMID:1540646 -3.4.11.9 arg-pro-pro-gly-phe bos taurus 48.0 48.0 1 PMID:1537867 -3.4.11.9 arg-pro-pro-gly-phe rattus norvegicus 15.0 15.0 1 PMID:7669781 -3.4.11.9 arg-pro-pro-gly-phe-ser bos taurus 30.0 30.0 1 PMID:1537867 -3.4.11.9 arg-pro-pro-gly-phe-ser rattus norvegicus 11.0 11.0 1 PMID:7669781 -3.4.11.9 arg-pro-pro-gly-phe-ser-pro bos taurus 41.0 41.0 1 PMID:1537867 -3.4.11.9 arg-pro-pro-gly-phe-ser-pro rattus norvegicus 16.0 16.0 1 PMID:7669781 -3.4.11.9 arg-pro-pro-gly-phe-ser-pro-phe bos taurus 39.0 39.0 1 PMID:1537867 -3.4.11.9 arg-pro-pro-gly-phe-ser-pro-phe rattus norvegicus 13.0 13.0 1 PMID:7669781 -3.4.11.9 arg-pro-pro-gly-phe-ser-pro-phe-arg bos taurus 26.0 26.0 1 PMID:1537867 -3.4.11.9 arg-pro-pro-gly-phe-ser-pro-phe-arg rattus norvegicus 12.0 12.0 1 PMID:7669781 -3.4.11.9 bradykinin escherichia coli 69.0 69.0 1 PMID:16460001 -3.4.11.9 bradykinin homo sapiens 11.0 4.140000000000001 4 PMID:11106490;PMID:18515364;PMID:29351301 -3.4.11.9 bradykinin plasmodium falciparum 160.0 88.0 3 PMID:19574214 -3.4.11.9 bradykinin rattus norvegicus 38.0 38.0 1 PMID:1645659 -3.4.11.9 bradykinin sus scrofa 6.08 3.63 2 PMID:11106491 -3.4.11.9 fphfd plasmodium falciparum 8.6 7.0 2 PMID:19574214 -3.4.11.9 gly-pro-hyp rattus norvegicus 69.0 58.5 2 PMID:7669781 -3.4.11.9 gly-pro-pro-p-nitroanilide rattus norvegicus 47.2 47.2 1 PMID:3338571 -3.4.11.9 l-ala-l-pro-4-nitroanilide streptomyces lividans 45.7 6.0 3 PMID:18156635 -3.4.11.9 l-ala-l-pro-4-nitroanilide streptomyces murinus 487.0 202.0 4 PMID:18156635 -3.4.11.9 l-ala-l-pro-l-ala escherichia coli 0.77 0.77 1 PMID:16411772 -3.4.11.9 l-arg-l-pro-l-pro homo sapiens 7.7 7.7 1 PMID:18515364 -3.4.11.9 l-arg-l-pro-l-pro-gly rattus norvegicus 17.0 17.0 1 PMID:7669781 -3.4.11.9 l-met-l-pro thermococcus onnurineus na1 541.0 541.0 1 PMID:16517635 -3.4.11.9 l-tyr-l-pro-l-phe-nh2 rattus norvegicus 58.0 58.0 1 PMID:1645659 -3.4.11.9 met-ala-ala deinococcus radiodurans 10.5 10.5 1 PMID:30536999 -3.4.11.9 met-ala-ala escherichia coli 1.5 1.5 1 PMID:30536999 -3.4.11.9 met-ala-ala mycobacterium tuberculosis 5.0 5.0 1 PMID:30536999 -3.4.11.9 met-pro deinococcus radiodurans 97.0 97.0 1 PMID:30536999 -3.4.11.9 met-pro escherichia coli 33.0 33.0 1 PMID:30536999 -3.4.11.9 met-pro mycobacterium tuberculosis 18.0 18.0 1 PMID:30536999 -3.4.11.9 met-pro-ala deinococcus radiodurans 242.0 242.0 1 PMID:30536999 -3.4.11.9 met-pro-ala escherichia coli 8.0 8.0 1 PMID:30536999 -3.4.11.9 met-pro-ala mycobacterium tuberculosis 126.0 126.0 1 PMID:30536999 -3.4.11.9 met-pro-ala saccharomyces cerevisiae 25.7 25.7 1 PMID:30582634 -3.4.11.9 substance p homo sapiens 3.1 3.1 1 PMID:11106490 -3.4.11.9 tyr-ala-ala saccharomyces cerevisiae 1.4 1.4 1 PMID:30582634 -3.4.11.9 tyr-pro-ala saccharomyces cerevisiae 14.0 14.0 1 PMID:30582634 -3.4.11.9 tyr-pro-leu-gly-nh2 rattus norvegicus 40.0 40.0 1 PMID:1645659 -3.4.11.9 tyr-pro-phe-pro-gly rattus norvegicus 32.0 32.0 1 PMID:1645659 -3.4.11.9 tyr-pro-phe-pro-gly-pro-ile rattus norvegicus 26.0 26.0 1 PMID:1645659 -3.4.11.9 ypwtq plasmodium falciparum 150.0 81.0 2 PMID:19574214 -3.4.13.18 ala-ala-p-nitroanilide homo sapiens 0.7 0.7 1 PMID:15039077 -3.4.13.18 ala-gly mus musculus 43.3 43.3 1 PMID:5542681 -3.4.13.18 ala-ile mus musculus 33300.0 33300.0 1 PMID:5542681 -3.4.13.18 ala-leu platyrrhini 6510.0 3850.0 2 PMID:4204951 -3.4.13.18 ala-pro-p-nitroanilide homo sapiens 40.0 31.0 2 PMID:15039077;PMID:17040910 -3.4.13.18 anserine homo sapiens 2.83 2.83 1 PMID:36529243 -3.4.13.18 arg-pro-p-nitroanilide homo sapiens 14.0 13.4 2 PMID:15039077;PMID:17040910 -3.4.13.18 asp-pro-p-nitroanilide homo sapiens 1.6 1.25 2 PMID:15039077;PMID:17040910 -3.4.13.18 gly-ile platyrrhini 23000.0 16850.0 2 PMID:4204951 -3.4.13.18 gly-leu platyrrhini 23100.0 17000.0 2 PMID:4204951 -3.4.13.18 gly-phe platyrrhini 20400.0 14295.0 2 PMID:4204951 -3.4.13.18 gly-pro-p-nitroanilide homo sapiens 62.0 43.5 2 PMID:15039077;PMID:17040910 -3.4.13.18 gly-val platyrrhini 21400.0 14425.0 2 PMID:4204951 -3.4.13.18 leu-pro-p-nitroanilide homo sapiens 7.0 7.0 1 PMID:17040910 -3.4.13.18 lys-pro-p-nitroanilide homo sapiens 3.2 3.2 1 PMID:17040910 -3.4.13.18 met-pro-p-nitroanilide homo sapiens 15.0 15.0 1 PMID:17040910 -3.4.13.18 ser-pro-p-nitroanilide homo sapiens 19.0 19.0 1 PMID:17040910 -3.4.13.19 l-ala-d-ala streptomyces coelicolor 750.0 750.0 1 PMID:20000809 -3.4.13.19 l-ala-l-asp streptomyces coelicolor 1400.0 1400.0 1 PMID:20000809 -3.4.13.19 l-ala-l-gln streptomyces coelicolor 140.0 140.0 1 PMID:20000809 -3.4.13.19 l-ala-l-glu streptomyces coelicolor 220.0 220.0 1 PMID:20000809 -3.4.13.19 l-arg-d-asp streptomyces coelicolor 107.0 107.0 1 PMID:20000809 -3.4.13.19 l-arg-l-asp streptomyces coelicolor 132.0 132.0 1 PMID:20000809 -3.4.13.19 l-asn-d-glu streptomyces coelicolor 288.0 288.0 1 PMID:20000809 -3.4.13.19 l-leu-d-ala streptomyces coelicolor 160.0 160.0 1 PMID:20000809 -3.4.13.19 l-leu-d-glu streptomyces coelicolor 135.0 135.0 1 PMID:20000809 -3.4.13.19 l-leu-d-leu streptomyces coelicolor 21.0 21.0 1 PMID:20000809 -3.4.13.19 l-leu-d-ser streptomyces coelicolor 400.0 400.0 1 PMID:20000809 -3.4.13.19 l-leu-l-asp streptomyces coelicolor 160.0 160.0 1 PMID:20000809 -3.4.13.19 l-leu-l-leu streptomyces coelicolor 140.0 140.0 1 PMID:20000809 -3.4.13.19 l-met-d-glu streptomyces coelicolor 340.0 340.0 1 PMID:20000809 -3.4.13.19 l-met-d-leu streptomyces coelicolor 194.0 194.0 1 PMID:20000809 -3.4.13.19 l-met-l-leu streptomyces coelicolor 310.0 310.0 1 PMID:20000809 -3.4.13.19 l-tyr-d-leu streptomyces coelicolor 24.0 24.0 1 PMID:20000809 -3.4.13.20 anserine homo sapiens 21.6 21.6 1 PMID:36529243 -3.4.13.20 beta-ala-4-nitroanilide brucella anthropi 30.5 30.5 1 PMID:17193247 -3.4.13.20 beta-ala-l-his homo sapiens 138.0 74.3 2 PMID:12473676 -3.4.13.20 beta-homoala-4-nitroanilide brucella anthropi 51.4 51.4 1 PMID:17193247 -3.4.13.20 beta-homophe-4-nitroanilide brucella anthropi 0.03 0.03 1 PMID:17193247 -3.4.13.20 d-ala-4-nitroanilide brucella anthropi 4.0 3.65 2 PMID:10377256 -3.4.13.20 gly-4-nitroanilide brucella anthropi 70.0 70.0 1 PMID:10377256 -3.4.13.20 homocarnosine homo sapiens 18.0 9.1 2 PMID:12473676 -3.4.13.20 l-ala-4-nitroanilide brucella anthropi 0.56 0.53 2 PMID:10377256 -3.4.13.20 l-arg-4-nitroanilide brucella anthropi 0.14 0.14 1 PMID:10377256 -3.4.13.20 l-lys-4-nitroanilide brucella anthropi 0.11 0.11 1 PMID:10377256 -3.4.13.21 l-asp-4-nitroanilide salmonella enterica subsp. enterica serovar typhimurium 39.0 19.61 2 PMID:11708790;PMID:8282693 -3.4.13.22 (2s)-n-d-alanyl-2-(phenylthio)-glycine enterococcus sp. 76.0 76.0 1 PMID:12823621 -3.4.13.22 co2+ enterococcus faecium 69.0 69.0 1 PMID:7873524 -3.4.13.22 d-ala-d-ala enterococcus faecalis 11.5 11.5 1 PMID:31071297 -3.4.13.22 d-ala-d-ala enterococcus faecium 156.0 60.0 9 PMID:15265748;PMID:15657055;PMID:17017774;PMID:7873524;PMID:8524812 -3.4.13.22 d-ala-d-ala enterococcus gallinarum 2.5 2.5 1 PMID:12047383 -3.4.13.22 d-ala-d-ala enterococcus sp. 460.1 84.65 4 PMID:11123924;PMID:12823621;PMID:9265630 -3.4.13.22 d-ala-d-ser enterococcus faecium 1.8 1.8 1 PMID:7873524 -3.4.13.22 d-ala-d-ser enterococcus gallinarum 0.35 0.35 1 PMID:12047383 -3.4.13.22 d-leu-4-nitroanilide enterococcus faecium 0.0102 0.0102 1 PMID:16701071 -3.4.13.22 d-leucine-p-nitroanilide enterococcus faecium 0.0102 0.0102 1 PMID:16701071 -3.4.13.22 d-ser-d-ala enterococcus faecium 0.35 0.35 1 PMID:7873524 -3.4.13.22 fe2+ enterococcus faecium 156.0 156.0 1 PMID:7873524 -3.4.13.22 ni2+ enterococcus faecium 788.0 788.0 1 PMID:7873524 -3.4.13.22 zn2+ enterococcus faecium 30.0 30.0 1 PMID:7873524 -3.4.13.9 ala-pro homo sapiens 22.0 22.0 1 PMID:17040910 -3.4.13.9 arg-pro xanthomonas campestris pv. campestris 19800.0 19800.0 1 PMID:27816563 -3.4.13.9 arg-pro-ala deinococcus radiodurans 240.0 240.0 1 PMID:30536999 -3.4.13.9 gly-pro aspergillus phoenicis 105.9 105.9 1 * -3.4.13.9 gly-pro homo sapiens 799.0 741.0 2 PMID:2713125;PMID:32515491 -3.4.13.9 gly-pro xanthomonas campestris pv. campestris 6100.0 6100.0 1 PMID:27816563 -3.4.13.9 his-pro xanthomonas campestris pv. campestris 3000.0 3000.0 1 PMID:27816563 -3.4.13.9 ile-pro cavia porcellus 55.3 55.3 1 PMID:6853481 -3.4.13.9 l-leu-l-pro cavia porcellus 111.0 111.0 1 PMID:6853481 -3.4.13.9 l-met-l-pro cavia porcellus 115.0 115.0 1 PMID:6853481 -3.4.13.9 l-met-l-pro escherichia coli 109.0 109.0 1 PMID:15313226 -3.4.13.9 leu-pro mycobacterium tuberculosis 1000.0 1000.0 1 PMID:27816563 -3.4.13.9 leu-pro pyrococcus horikoshii 1079.0 1079.0 1 PMID:22162664 -3.4.13.9 leu-pro xanthomonas campestris pv. campestris 5000.0 5000.0 1 PMID:27816563 -3.4.13.9 lys-pro aspergillus phoenicis 123.5 123.5 1 * -3.4.13.9 lys-pro deinococcus radiodurans 349.0 349.0 1 PMID:28929533 -3.4.13.9 lys-pro xanthomonas campestris pv. campestris 5700.0 5700.0 1 PMID:27816563 -3.4.13.9 met-ala-ala deinococcus radiodurans 10.5 10.5 1 PMID:30536999 -3.4.13.9 met-ala-ala escherichia coli 1.5 1.5 1 PMID:30536999 -3.4.13.9 met-ala-ala mycobacterium tuberculosis 5.0 5.0 1 PMID:30536999 -3.4.13.9 met-ala-ala pyrococcus furiosus 27.0 27.0 2 PMID:30536999 -3.4.13.9 met-pro deinococcus radiodurans 178.0 137.5 2 PMID:28929533;PMID:30536999 -3.4.13.9 met-pro escherichia coli 33.0 33.0 1 PMID:30536999 -3.4.13.9 met-pro mycobacterium tuberculosis 18.0 18.0 1 PMID:30536999 -3.4.13.9 met-pro pyrococcus furiosus 4594.0 767.0 10 PMID:20422176;PMID:30536999 -3.4.13.9 met-pro pyrococcus horikoshii 3812.0 3214.5 2 PMID:19784642 -3.4.13.9 met-pro xanthomonas campestris pv. campestris 9100.0 9100.0 1 PMID:27816563 -3.4.13.9 met-pro-ala deinococcus radiodurans 242.0 242.0 1 PMID:30536999 -3.4.13.9 met-pro-ala escherichia coli 8.0 8.0 1 PMID:30536999 -3.4.13.9 met-pro-ala mycobacterium tuberculosis 126.0 126.0 1 PMID:30536999 -3.4.13.9 met-pro-ala pyrococcus furiosus 192.0 192.0 2 PMID:30536999 -3.4.13.9 paraoxon homo sapiens 3.0 3.0 1 PMID:32515491 -3.4.13.9 phe-pro deinococcus radiodurans 256.0 256.0 1 PMID:28929533 -3.4.13.9 phe-pro xanthomonas campestris pv. campestris 16900.0 16900.0 1 PMID:27816563 -3.4.13.9 pro-pro xanthomonas campestris pv. campestris 4500.0 4500.0 1 PMID:27816563 -3.4.13.9 tyr-pro xanthomonas campestris pv. campestris 12500.0 12500.0 1 PMID:27816563 -3.4.13.9 val-pro xanthomonas campestris pv. campestris 3000.0 3000.0 1 PMID:27816563 -3.4.14.1 asn1-angiotensin ii rattus norvegicus 87.0 87.0 1 PMID:4358631 -3.4.14.1 benzyloxyarbonyl-gly-l-pro-l-arg-7-amido-4-methylcoumarin homo sapiens 0.13 0.13 1 PMID:30703555 -3.4.14.1 benzyloxycarbonyl-l-leu-l-arg-7-amido-4-methylcoumarin homo sapiens 0.18 0.18 1 PMID:30703555 -3.4.14.1 benzyloxycarbonyl-l-phe-l-arg-7-amido-4-methylcoumarin homo sapiens 0.23 0.23 1 PMID:30703555 -3.4.14.1 beta-(2-thienyl)ala-beta-(7-methoxycoumarin-4-yl)ala-ser-gln-tyr(3-no2)-nh2 homo sapiens 6.19 5.82 2 PMID:27746119 -3.4.14.1 beta-(2-thienyl)ala-beta-(7-methoxycoumarin-4-yl)ala-ser-gly-tyr(3-no2)-nh2 homo sapiens 4.29 3.87 2 PMID:27746119 -3.4.14.1 beta-(2-thienyl)ala-beta-(7-methoxycoumarin-4-yl)ala-ser-tyr(3-no2)-nh2 homo sapiens 2.51 2.17 2 PMID:27746119 -3.4.14.1 beta-(2-thienyl)ala-phe-7-amido-4-methylcoumarin homo sapiens 3.5 2.785 2 PMID:27746119 -3.4.14.1 glucagon rattus norvegicus 81.0 81.0 1 PMID:5389103 -3.4.14.1 gly-gly-ethyl ester bos taurus 74.0 74.0 1 PMID:5758556 -3.4.14.1 gly-l-phe-7-amido-4-methylcoumarin homo sapiens 12.2 7.08 2 PMID:31574257 -3.4.14.1 gly-leu-ethyl ester bos taurus 126.0 126.0 1 PMID:5758556 -3.4.14.1 gly-phe-ethyl ester bos taurus 98.0 98.0 1 PMID:5758556 -3.4.14.1 gly-phe-methyl ester bos taurus 61.0 61.0 1 PMID:5758556 -3.4.14.1 gly-trp-methyl ester bos taurus 293.0 293.0 1 PMID:5758556 -3.4.14.1 gly-tyr-ethyl ester bos taurus 90.0 90.0 1 PMID:5758556 -3.4.14.1 glycyl-(beta-phenyl)l-lactic acid methyl ester bos taurus 210.0 210.0 1 PMID:5758556 -3.4.14.1 his-ser-2-naphthylamide rattus norvegicus 116.0 116.0 1 PMID:5389103 -3.4.14.1 ile5-angiotensin ii rattus norvegicus 87.0 87.0 1 PMID:4358631 -3.4.14.1 sarcosyl-phe-ethyl ester bos taurus 157.0 157.0 1 PMID:5758556 -3.4.14.1 t-butyloxycarbonyl-l-val-l-leu-l-lys-7-amido-4-methylcoumarin homo sapiens 0.16 0.16 1 PMID:30703555 -3.4.14.10 ala-ala-ala-4-nitroanilide drosophila melanogaster 13.0 12.0 5 PMID:22266401 -3.4.14.10 ala-ala-ala-4-nitroanilide homo sapiens 5.0 3.3 5 PMID:22266401 -3.4.14.10 ala-ala-ala-4-nitroanilide mus musculus 33.0 30.0 5 PMID:22266401 -3.4.14.10 ala-ala-phe-4-nitroanilide drosophila melanogaster 65.0 57.0 5 PMID:22266401 -3.4.14.10 ala-ala-phe-4-nitroanilide homo sapiens 27.0 19.0 5 PMID:22266401 -3.4.14.10 ala-ala-phe-4-nitroanilide kitasatospora herbaricolor 43.0 43.0 1 PMID:28674833 -3.4.14.10 ala-ala-phe-4-nitroanilide mus musculus 114.0 56.8 5 PMID:22266401 -3.4.14.10 l-ala-l-ala-l-ala 4-nitroanilide drosophila melanogaster 13.0 12.0 5 PMID:22266401 -3.4.14.10 l-ala-l-ala-l-ala 4-nitroanilide homo sapiens 5.0 3.3 5 PMID:22266401 -3.4.14.10 l-ala-l-ala-l-ala 4-nitroanilide mus musculus 33.0 30.0 5 PMID:22266401 -3.4.14.10 l-ala-l-ala-l-phe 4-nitroanilide drosophila melanogaster 65.0 57.0 5 PMID:22266401 -3.4.14.10 l-ala-l-ala-l-phe 4-nitroanilide homo sapiens 27.0 19.0 5 PMID:22266401 -3.4.14.10 l-ala-l-ala-l-phe 4-nitroanilide mus musculus 125.0 96.0 5 PMID:22266401 -3.4.14.11 ala-pro-4-nitroanilide lactobacillus helveticus 128.0 128.0 1 * -3.4.14.11 ala-pro-arg lactobacillus helveticus 57.2 57.2 1 * -3.4.14.11 arg-pro 4-nitroanilide lactococcus lactis 181.0 181.0 1 PMID:1369485 -3.4.14.11 arg-pro-ala lactobacillus helveticus 133.0 133.0 1 * -3.4.14.11 glu-pro-7-amido-4-methylcoumarin lactococcus lactis 62.9 62.9 1 * -3.4.14.11 gly-ala-7-amido-4-methylcoumarin lactococcus lactis 2.1 2.1 1 * -3.4.14.11 gly-pro 4-nitroanilide lactococcus lactis 178.0 178.0 1 PMID:1369485 -3.4.14.11 gly-pro-7-amido-4-methylcoumarin lactococcus lactis 69.8 65.95 2 * -3.4.14.11 gly-pro-ala lactococcus lactis 2180.0 2180.0 1 PMID:1369485 -3.4.14.11 gly-pro-glp-1(7-37) lactococcus cremoris 57.5 57.5 1 PMID:32007557 -3.4.14.11 gly-pro-gly-gly lactococcus lactis 46.4 46.4 1 * -3.4.14.11 his-pro-leu lactococcus lactis 418.0 418.0 1 PMID:1369485 -3.4.14.11 his-pro-tyr lactococcus lactis 670.0 670.0 1 PMID:1369485 -3.4.14.11 l-ala-l-ala-7-amido-4-methylcoumarin lactococcus lactis 26.0 26.0 1 PMID:1369485 -3.4.14.11 l-ala-l-pro-l-arg lactobacillus helveticus 57.2 57.2 1 * -3.4.14.11 l-ala-l-pro-l-ser lactobacillus helveticus 95.9 95.9 1 * -3.4.14.11 l-ala-l-pro-l-tyr lactobacillus helveticus 43.5 43.5 1 * -3.4.14.11 l-arg-l-pro-l-ala lactobacillus helveticus 133.0 133.0 1 * -3.4.14.11 l-asp-l-pro-l-ala lactobacillus helveticus 199.0 199.0 1 * -3.4.14.11 l-ser-l-pro-l-ala lactobacillus helveticus 233.0 233.0 1 * -3.4.14.11 l-tyr-l-pro-l-ala lactobacillus helveticus 145.0 145.0 1 * -3.4.14.11 leu-ala-pro lactococcus lactis 120.0 120.0 1 PMID:1369485 -3.4.14.11 leu-pro-7-amido-4-methylcoumarin lactococcus lactis 43.4 43.4 1 * -3.4.14.11 lys-ala-7-amido-4-methylcoumarin lactococcus lactis 17.1 17.1 1 * -3.4.14.11 lys-pro-7-amido-4-methylcoumarin lactococcus lactis 61.6 61.6 1 * -3.4.14.11 phe-pro-7-amido-4-methylcoumarin lactococcus lactis 78.4 78.4 1 * -3.4.14.11 ser-pro-ala lactobacillus helveticus 233.0 233.0 1 * -3.4.14.11 tyr-pro-ala lactobacillus helveticus 145.0 145.0 1 * -3.4.14.12 gly-ala-pro-2-naphthylamide porphyromonas gingivalis 511.0 354.0 3 PMID:16914159;PMID:18042490 -3.4.14.12 gly-ala-pro-beta-naphthylamide porphyromonas gingivalis 354.0 178.325 2 PMID:18042490 -3.4.14.12 gly-l-ala-gly-l-pro-beta-naphthylamide streptomyces mobaraensis 43.0 43.0 1 PMID:15598885 -3.4.14.12 gly-l-ala-l-pro-beta-naphthylamide streptomyces mobaraensis 115.0 115.0 1 PMID:15598885 -3.4.14.13 l-ala-gamma-d-glu-l-lys bacillus subtilis 1.2 1.2 1 PMID:11747447 -3.4.14.13 l-ala-gamma-d-glu-l-lys-d-ala bacillus subtilis 2.6 2.6 1 PMID:11747447 -3.4.14.13 l-ala-gamma-d-glu-l-lys-d-ala-d-ala bacillus subtilis 5.7 5.7 1 PMID:11747447 -3.4.14.2 ala-ala-4-nitroanilide rattus norvegicus 314.0 314.0 1 PMID:6342678 -3.4.14.2 ala-ala-ala rattus norvegicus 121.0 121.0 1 PMID:6342678 -3.4.14.2 ala-pro-p-nitroanilide homo sapiens 105.4 97.2 4 PMID:15487984;PMID:17352682 -3.4.14.2 arg-pro-2-naphthylamide sus scrofa 6.4 6.4 1 PMID:3722177 -3.4.14.2 arg-pro-p-nitroanilide homo sapiens 65.8 65.8 1 PMID:15487984 -3.4.14.2 asn-pro-p-nitroanilide homo sapiens 184.6 184.6 1 PMID:15487984 -3.4.14.2 gly-ala-ala rattus norvegicus 103.0 103.0 1 PMID:6342678 -3.4.14.2 gly-l-pro-4-nitroanilide bos taurus 11.5 9.15 2 PMID:18774942 -3.4.14.2 gly-pro-4-nitroanilide rattus norvegicus 109.0 109.0 1 PMID:6342678 -3.4.14.2 gly-pro-ala rattus norvegicus 120.0 120.0 1 PMID:6342678 -3.4.14.2 gly-pro-p-nitroanilide homo sapiens 67.3 67.3 2 PMID:15487984;PMID:17352682 -3.4.14.2 his-ala-p-nitroanilide homo sapiens 12.8 12.8 1 PMID:15487984 -3.4.14.2 his-pro-p-nitroanilide homo sapiens 28.4 28.4 1 PMID:15487984 -3.4.14.2 lys-ala-2-naphthylamide rattus norvegicus 536.0 536.0 1 PMID:6342678 -3.4.14.2 lys-ala-2-naphthylamide sus scrofa 6.0 6.0 1 PMID:3722177 -3.4.14.2 lys-ala-p-nitroanilide homo sapiens 229.3 229.3 1 PMID:15487984 -3.4.14.2 lys-pro-p-nitroanilide homo sapiens 77.7 40.35 4 PMID:15487984;PMID:17352682 -3.4.14.2 nle-nle-p-nitroanilide homo sapiens 18.4 18.4 1 PMID:15487984 -3.4.14.2 phe-pro-2-naphthylamide sus scrofa 54.0 54.0 1 PMID:3722177 -3.4.14.2 phe-pro-p-nitroanilide homo sapiens 93.0 93.0 1 PMID:15487984 -3.4.14.2 pro-ala-p-nitroanilide homo sapiens 15.3 15.3 1 PMID:15487984 -3.4.14.2 ser-pro-p-nitroanilide homo sapiens 116.9 91.45 2 PMID:15487984 -3.4.14.2 tyr-ala-p-nitroanilide homo sapiens 11.0 11.0 1 PMID:15487984 -3.4.14.4 ala-ala-2-naphthylamide arabidopsis thaliana 0.0338 0.0338 1 PMID:27467751 -3.4.14.4 ala-ala-2-naphthylamide homo sapiens 0.35 0.35 1 PMID:19375145 -3.4.14.4 ala-arg-2-naphthylamide arabidopsis thaliana 0.0415 0.0415 1 PMID:27467751 -3.4.14.4 ala-arg-2-naphthylamide physcomitrium patens 0.0106 0.0106 1 PMID:27467751 -3.4.14.4 arg-arg-2-naphthylamide arabidopsis thaliana 0.002 0.002 1 PMID:27467751 -3.4.14.4 arg-arg-2-naphthylamide homo sapiens 35.4 26.65 4 PMID:17338643;PMID:18163885;PMID:19375145 -3.4.14.4 arg-arg-2-naphthylamide physcomitrium patens 0.0137 0.0137 1 PMID:27467751 -3.4.14.4 arg-arg-2-naphthylamide porphyromonas gingivalis 0.75 0.75 1 PMID:29190734 -3.4.14.4 arg-arg-2-naphthylamide saccharomyces cerevisiae 0.334 0.2915 2 PMID:19825391 -3.4.14.4 arg-arg-2-naphtylamide caldithrix abyssi 3.07 1.635 2 PMID:29420664 -3.4.14.4 arg-arg-4-methoxy-beta-naphthylamide capra hircus 0.039 0.039 1 PMID:17182254 -3.4.14.4 arg-arg-4-methylcoumarin 7-amide porphyromonas gingivalis 0.29 0.29 1 PMID:29190734 -3.4.14.4 gly-arg-2-naphtylamide caldithrix abyssi 2.53 2.53 1 PMID:29420664 -3.4.14.4 gly-gly-phe-leu rattus norvegicus 50.0 50.0 1 PMID:3297170 -3.4.14.4 hemorphin-4 homo sapiens 6.11 6.11 1 PMID:36116590 -3.4.14.4 l-ala-l-ala 2-naphthylamide saccharomyces cerevisiae 0.777 0.777 1 PMID:24136327 -3.4.14.4 l-arg-l-arg 2-naphthylamide saccharomyces cerevisiae 0.248 0.138 2 PMID:24136327 -3.4.14.4 l-arg-l-arg-2-naphthylamide corallococcus sp. egb 1.34 1.34 1 PMID:36614072 -3.4.14.4 l-arg-l-arg-2-naphthylamide homo sapiens 21.4 12.57 2 PMID:31496375;PMID:36838964 -3.4.14.4 l-leu-enkephalin homo sapiens 1.08 1.08 1 PMID:36116590 -3.4.14.4 l-leu-valorphin-l-arg homo sapiens 0.35 0.35 1 PMID:36116590 -3.4.14.4 l-lys-l-ala-2-naphthylamide rattus norvegicus 1.4 0.8999999999999999 2 PMID:22683474 -3.4.14.4 pro-arg-2-naphthylamide arabidopsis thaliana 0.0372 0.0372 1 PMID:27467751 -3.4.14.4 trp-met-asp-phe-nh2 rattus norvegicus 167.0 167.0 1 PMID:3297170 -3.4.14.4 tyr-gly-gly-phe-leu rattus norvegicus 13.2 13.2 1 PMID:3297170 -3.4.14.4 tyr-pro-trp-phe-nh2 homo sapiens 5.0 5.0 1 PMID:17338643 -3.4.14.5 ala-ala-4-nitroanilide lactococcus lactis 26.0 26.0 1 PMID:1369485 -3.4.14.5 ala-pro-7-amido-4-methylcoumarin homo sapiens 23.0 23.0 1 PMID:14691230 -3.4.14.5 ala-pro-7-amido-4-methylcoumarin hordeum vulgare 23.0 23.0 1 PMID:10677435 -3.4.14.5 ala-pro-7-amido-4-trifluoromethyl coumarin homo sapiens 43.1 39.6 3 PMID:12906826 -3.4.14.5 ala-pro-7-amido-4-trifluoromethylcoumarin homo sapiens 18.0 18.0 1 PMID:14691230 -3.4.14.5 amyloid beta40 bos taurus 0.063 0.063 1 PMID:23579020 -3.4.14.5 amyloid beta42 bos taurus 0.027 0.027 1 PMID:23579020 -3.4.14.5 arg-pro-4-nitroanilide lactococcus lactis 181.0 181.0 1 PMID:1369485 -3.4.14.5 arg-pro-7-amido-4-methylcoumarin hordeum vulgare 71.0 71.0 1 PMID:10677435 -3.4.14.5 arg-pro-lys-pro rattus norvegicus 66.1 66.1 1 PMID:2461166 -3.4.14.5 arg-pro-lys-pro-gln-gln-phe-gly rattus norvegicus 62.3 62.3 1 PMID:2461166 -3.4.14.5 arg-pro-lys-pro-gln-gln-phe-phe-gly rattus norvegicus 60.3 60.3 1 PMID:2461166 -3.4.14.5 arg-pro-lys-pro-gln-gln-phe-phe-gly-leu-met-nh2 rattus norvegicus 50.3 50.3 1 PMID:2461166 -3.4.14.5 asn-pro-7-amido-4-methylcoumarin hordeum vulgare 35.0 35.0 1 PMID:10677435 -3.4.14.5 asp-pro-7-amido-4-methylcoumarin hordeum vulgare 4.6 4.6 1 PMID:10677435 -3.4.14.5 bri peptide (1-23) homo sapiens 5.2 5.2 1 PMID:18940185 -3.4.14.5 gln-pro-7-amido-4-methylcoumarin hordeum vulgare 10.0 10.0 1 PMID:10677435 -3.4.14.5 glu-pro-7-amido-4-methylcoumarin hordeum vulgare 10.0 10.0 1 PMID:10677435 -3.4.14.5 glu-pro-7-amido-4-methylcoumarin lactococcus lactis 62.9 62.9 1 * -3.4.14.5 gly-ala-7-amido-4-methylcoumarin lactococcus lactis 2.1 2.1 1 * -3.4.14.5 gly-l-ala-2-naphthylamide rattus norvegicus 5.6 5.6 1 PMID:6756314 -3.4.14.5 gly-l-pro-2-naphthylamide rattus norvegicus 128.0 128.0 1 PMID:6756314 -3.4.14.5 gly-l-pro-7-amido-4-methylcoumarin pseudoxanthomonas mexicana 19.2 19.2 1 PMID:29426867 -3.4.14.5 gly-l-pro-gly-gly rattus norvegicus 31.3 31.3 1 PMID:6756314 -3.4.14.5 gly-l-pro-l-ala rattus norvegicus 82.3 82.3 1 PMID:6756314 -3.4.14.5 gly-l-pro-p-nitroanilide homo sapiens 20.3 20.3 1 PMID:19268648 -3.4.14.5 gly-pro-3,5-dibromo-4-hydroxyanilide homo sapiens 810.0 810.0 1 PMID:8951616 -3.4.14.5 gly-pro-4-nitroanilide homo sapiens 279000.0 24.0 3 PMID:14691230;PMID:15175333 -3.4.14.5 gly-pro-4-nitroanilide lactococcus lactis 178.0 120.05 2 PMID:1369485 -3.4.14.5 gly-pro-4-nitroanilide rattus norvegicus 52.3 52.3 1 PMID:14987798 -3.4.14.5 gly-pro-7-amido-4-methylcoumarin hordeum vulgare 60.0 60.0 1 PMID:10677435 -3.4.14.5 gly-pro-7-amido-4-methylcoumarin lactococcus lactis 69.8 69.8 1 * -3.4.14.5 gly-pro-ala lactococcus lactis 2180.0 2180.0 1 PMID:1369485 -3.4.14.5 gly-pro-p-nitroanilide homo sapiens 87.0 87.0 1 PMID:16752891 -3.4.14.5 hemorphin-4 rattus norvegicus 1774.0 1772.0 2 PMID:14987798 -3.4.14.5 hemorphin-7 rattus norvegicus 5.3 5.3 1 PMID:14987798 -3.4.14.5 his-pro-7-amido-4-methylcoumarin hordeum vulgare 41.0 41.0 1 PMID:10677435 -3.4.14.5 his-pro-leu lactococcus lactis 418.0 418.0 1 PMID:1369485 -3.4.14.5 his-pro-tyr lactococcus lactis 670.0 670.0 1 PMID:1369485 -3.4.14.5 ile-pro-7-amido-4-methylcoumarin hordeum vulgare 67.0 67.0 1 PMID:10677435 -3.4.14.5 l-ala-l-ala-2-naphthylamide rattus norvegicus 52.3 52.3 1 PMID:6756314 -3.4.14.5 l-ala-l-ala-l-ala rattus norvegicus 15.1 15.1 1 PMID:6756314 -3.4.14.5 l-ala-l-pro-gly rattus norvegicus 46.2 46.2 1 PMID:6756314 -3.4.14.5 l-ala-l-pro-p-nitroanilide homo sapiens 33.0 33.0 1 PMID:19268648 -3.4.14.5 l-arg-l-pro-p-nitroanilide homo sapiens 7.7 7.7 1 PMID:19268648 -3.4.14.5 l-asn-l-pro-p-nitroanilide homo sapiens 11.0 11.0 1 PMID:19268648 -3.4.14.5 l-glu-l-pro-p-nitroanilide homo sapiens 7.0 7.0 1 PMID:19268648 -3.4.14.5 l-leu-l-ala-2-naphthylamide rattus norvegicus 11.2 11.2 1 PMID:6756314 -3.4.14.5 l-leu-l-leu-gly rattus norvegicus 1.5 1.5 1 PMID:6756314 -3.4.14.5 l-leu-l-leu-l-leu rattus norvegicus 2.7 2.7 1 PMID:6756314 -3.4.14.5 l-leu-l-pro-gly-gly rattus norvegicus 82.8 82.8 1 PMID:6756314 -3.4.14.5 l-leu-l-pro-p-nitroanilide homo sapiens 6.3 6.3 1 PMID:19268648 -3.4.14.5 l-lys-l-ala-2-naphthylamide rattus norvegicus 6.3 6.3 1 PMID:6756314 -3.4.14.5 l-lys-l-pro-p-nitroanilide homo sapiens 5.0 5.0 1 PMID:19268648 -3.4.14.5 l-met-l-pro-p-nitroanilide homo sapiens 8.7 8.7 1 PMID:19268648 -3.4.14.5 l-phe-l-pro-2-naphthylamide rattus norvegicus 990.0 990.0 1 PMID:6756314 -3.4.14.5 l-ser-l-pro-p-nitroanilide homo sapiens 18.0 18.0 1 PMID:19268648 -3.4.14.5 l-thr-l-pro-7-amido-4-methylcoumarin hordeum vulgare 117.0 117.0 1 PMID:10677435 -3.4.14.5 leu-ala-pro lactococcus lactis 120.0 120.0 1 PMID:1369485 -3.4.14.5 leu-pro-7-amido-4-methylcoumarin hordeum vulgare 22.0 22.0 1 PMID:10677435 -3.4.14.5 leu-pro-7-amido-4-methylcoumarin lactococcus lactis 43.8 43.8 1 * -3.4.14.5 lys-ala-7-amido-4-methylcoumarin hordeum vulgare 92.0 92.0 1 PMID:10677435 -3.4.14.5 lys-ala-7-amido-4-methylcoumarin lactococcus lactis 17.1 17.1 1 * -3.4.14.5 lys-pro-7-amido-4-methylcoumarin hordeum vulgare 90.0 90.0 1 PMID:10677435 -3.4.14.5 lys-pro-7-amido-4-methylcoumarin lactococcus lactis 61.6 61.6 1 * -3.4.14.5 lys-pro-gln-gln-phe-phe-gly-leu-met-nh2 rattus norvegicus 88.3 88.3 1 PMID:2461166 -3.4.14.5 met-pro-7-amido-4-methylcoumarin hordeum vulgare 102.0 102.0 1 PMID:10677435 -3.4.14.5 n-(ala-pro)-n'-6-(3,4-dichloromaleimidyl)-hexanoyl-rhodamine 110 sus scrofa 0.55 0.55 1 PMID:12095981 -3.4.14.5 n-(gly-pro)-n'-(4-chlorobutanoyl)-rhodamine 110 sus scrofa 0.7 0.7 1 PMID:12095981 -3.4.14.5 n-(gly-pro)-n'-(4-chloromethyl)benzoyl-rhodamine 110 sus scrofa 3.4 3.4 1 PMID:12095981 -3.4.14.5 n-(gly-pro)-n'-(5-bromopentanoyl)-rhodamine 110 sus scrofa 3.22 3.22 1 PMID:12095981 -3.4.14.5 n-(gly-pro)-n'-(5-chloropentanoyl)-rhodamine 110 sus scrofa 8.0 8.0 1 PMID:12095981 -3.4.14.5 n-(gly-pro)-n'-4-(maleimidyl)butanoyl-rhodamine 110 sus scrofa 8.0 8.0 1 PMID:12095981 -3.4.14.5 n-(gly-pro)-n'-chloroacetyl-rhodamine 110 sus scrofa 1.6 1.6 1 PMID:12095981 -3.4.14.5 phe-pro-7-amido-4-methylcoumarin hordeum vulgare 1.8 1.8 1 PMID:10677435 -3.4.14.5 phe-pro-7-amido-4-methylcoumarin lactococcus lactis 78.4 78.4 1 * -3.4.14.5 pro-pro-7-amido-4-methylcoumarin hordeum vulgare 41.0 41.0 1 PMID:10677435 -3.4.14.5 ser-pro-7-amido-4-methylcoumarin hordeum vulgare 58.0 58.0 1 PMID:10677435 -3.4.14.5 tyr-pro-7-amido-4-methylcoumarin hordeum vulgare 99.0 99.0 1 PMID:10677435 -3.4.14.5 tyr-pro-phe rattus norvegicus 87.5 87.5 1 PMID:2461166 -3.4.14.5 tyr-pro-phe-pro rattus norvegicus 90.8 90.8 1 PMID:2461166 -3.4.14.5 tyr-pro-phe-pro-gly rattus norvegicus 102.0 102.0 1 PMID:2461166 -3.4.14.5 tyr-pro-phe-val-glu-pro-ile rattus norvegicus 71.4 71.4 1 PMID:2461166 -3.4.14.5 tyr-pro-phe-val-glu-pro-ileu rattus norvegicus 103.0 103.0 1 PMID:2461166 -3.4.14.9 ala-ala-phe-4-nitroanilide dictyostelium discoideum 550000.0 550000.0 1 PMID:10410254 -3.4.14.9 ala-ala-phe-7-amido-4-carbamoylmethylcoumarin homo sapiens 5.3 5.3 1 PMID:16339154 -3.4.14.9 ala-ala-phe-7-amido-4-methylcoumarin homo sapiens 41.66 5.2 3 PMID:15733845;PMID:16339154 -3.4.14.9 ala-ala-phe-7-amido-4-methylcoumarin rattus norvegicus 33.1 33.1 1 PMID:11843185 -3.4.14.9 ala-ala-phe-p-nitrophenylalanyl-arg-leu homo sapiens 34.5 34.5 1 PMID:16091586 -3.4.14.9 ala-ala-pro-4-nitroanilide dictyostelium discoideum 210000.0 210000.0 1 PMID:10410254 -3.4.14.9 ala-arg-phe-p-nitrophenylalanyl-arg-leu homo sapiens 11.8 11.8 1 PMID:16091586 -3.4.14.9 ala-asp-phe-p-nitrophenylalanyl-arg-leu homo sapiens 11.0 11.0 1 PMID:16091586 -3.4.14.9 ala-his-phe-p-nitrophenylalanyl-arg-leu homo sapiens 26.4 26.4 1 PMID:16091586 -3.4.14.9 ala-nle-leu-7-amido-4-carbamoylmethylcoumarin homo sapiens 3.6 3.6 1 PMID:16339154 -3.4.14.9 ala-nle-nle-7-amido-4-carbamoylmethylcoumarin homo sapiens 4.2 4.2 1 PMID:16339154 -3.4.14.9 ala-nva-nle-7-amido-4-carbamoylmethylcoumarin homo sapiens 4.7 4.7 1 PMID:16339154 -3.4.14.9 ala-phe-pro-p-nitroanilide dictyostelium discoideum 140000.0 140000.0 1 PMID:10410254 -3.4.14.9 ala-ser-phe-p-nitrophenylalanyl-arg-leu homo sapiens 30.7 30.7 1 PMID:16091586 -3.4.14.9 arg-ala-phe-p-nitrophenylalanyl-arg-leu homo sapiens 0.91 0.91 1 PMID:16091586 -3.4.14.9 arg-pro-phe-7-amido-4-carbamoylmethylcoumarin homo sapiens 8.2 8.2 1 PMID:16339154 -3.4.14.9 asp-ala-phe-p-nitrophenylalanyl-arg-leu homo sapiens 18.5 18.5 1 PMID:16091586 -3.4.14.9 his-ala-phe-p-nitrophenylalanyl-arg-leu homo sapiens 13.7 13.7 1 PMID:16091586 -3.4.14.9 kwffiq-[n-(2,4-dinitrophenyl)-ethylenediamine] homo sapiens 2.0 2.0 1 PMID:26775801 -3.4.14.9 phe-pro-ala-4-nitroanilide aspergillus fumigatus 35.0 35.0 1 PMID:16517617 -3.4.14.9 rwffiq-[n-(2,4-dinitrophenyl)-ethylenediamine] homo sapiens 5.04 5.04 1 PMID:26775801 -3.4.14.9 rwfviq-[n-(2,4-dinitrophenyl)-ethylenediamine] homo sapiens 1.5 1.5 1 PMID:26775801 -3.4.14.9 ser-ala-phe-p-nitrophenylalanyl-arg-leu homo sapiens 4.7 4.7 1 PMID:16091586 -3.4.15.1 2-furanacryloyl-phe-gly-gly homo sapiens 368.0 344.0 2 PMID:1848554 -3.4.15.1 2-furanacryloyl-phe-gly-gly struthio camelus 987.0 987.0 1 * -3.4.15.1 2-furylacryloyl-phe-gly-gly sus scrofa 7590.0 6555.0 2 PMID:12450545 -3.4.15.1 [arg10]angiotensin i homo sapiens 460.0 460.0 1 PMID:15615692 -3.4.15.1 [phe9,arg10]angiotensin i homo sapiens 1400.0 1400.0 1 PMID:15615692 -3.4.15.1 [phe9]angiotensin i homo sapiens 550.0 550.0 1 PMID:15615692 -3.4.15.1 abz-frk(dnp)p-oh ucides cordatus 1.9 1.9 1 PMID:25544039 -3.4.15.1 abz-lfk(dnp)-oh homo sapiens 23.0 23.0 1 PMID:24228790 -3.4.15.1 abz-lfk(dnp)-oh ucides cordatus 0.8 0.8 1 PMID:25544039 -3.4.15.1 abz-sdk(dnp)p-oh homo sapiens 3.0 3.0 1 PMID:24228790 -3.4.15.1 amyloid beta-protein 1-42 homo sapiens 4.2 4.2 1 PMID:17687040 -3.4.15.1 angiotensin homo sapiens 8.33 4.455 2 PMID:16246972;PMID:2987059 -3.4.15.1 angiotensin i drosophila sp. (in: flies) 11.06 6.83 7 PMID:16403023 -3.4.15.1 angiotensin i gallus gallus 6.58 4.765000000000001 2 PMID:1311747 -3.4.15.1 angiotensin i homo sapiens 52.0 30.35 2 PMID:15615692;PMID:16246972 -3.4.15.1 angiotensin i oryctolagus cuniculus 13.5 12.6 4 PMID:17485083;PMID:6305731;PMID:6754723 -3.4.15.1 angiotensin i rattus norvegicus 1.4 1.4 1 PMID:14499287 -3.4.15.1 arg-pro-pro-gly-phe-ser-pro-tyr-arg drosophila sp. (in: flies) 2.41 2.41 1 PMID:16403023 -3.4.15.1 arg-pro-pro-gly-phe-thr-pro-phe-arg drosophila sp. (in: flies) 0.24 0.24 1 PMID:16403023 -3.4.15.1 benzoyl-gly-gly-gly homo sapiens 283.0 283.0 1 PMID:6281622 -3.4.15.1 benzoyl-gly-his-leu alitta virens 345.0 345.0 1 PMID:10825662 -3.4.15.1 benzoyl-gly-his-leu homo sapiens 76.7 76.7 1 PMID:6281622 -3.4.15.1 benzoyl-gly-phe-arg homo sapiens 383.0 383.0 1 PMID:6281622 -3.4.15.1 benzyloxycarbonyl-phe-his-leu bos taurus 100.0 21.5 3 PMID:11403651;PMID:12935891;PMID:16271036 -3.4.15.1 benzyloxycarbonyl-phe-his-leu homo sapiens 128.0 55.0 6 PMID:16895474 -3.4.15.1 bradykinin drosophila sp. (in: flies) 1.09 1.09 1 PMID:16403023 -3.4.15.1 bradykinin homo sapiens 8.33 8.33 1 PMID:2987059 -3.4.15.1 bradykinin oryctolagus cuniculus 9.1 9.1 1 PMID:183603 -3.4.15.1 furanacryloyl-l-phe-gly-gly homo sapiens 179.0 179.0 1 PMID:2982846 -3.4.15.1 furanacryloyl-l-phe-gly-gly oryctolagus cuniculus 210.0 210.0 1 PMID:2982846 -3.4.15.1 hippuryl-his-leu gallus gallus 8.58 6.99 2 PMID:1311747 -3.4.15.1 hippuryl-his-leu homo sapiens 545.0 196.0 9 PMID:12542396;PMID:16895474;PMID:1848554;PMID:6279576 -3.4.15.1 hippuryl-his-leu oryctolagus cuniculus 308.0 302.0 3 PMID:169257;PMID:183603;PMID:6305731;PMID:6754723 -3.4.15.1 ile-ser-arg-pro-pro-gly-phe-ser-pro-phe-arg drosophila sp. (in: flies) 1.1 1.1 1 PMID:16403023 -3.4.15.1 leu5-enkephalin homo sapiens 11.7 11.7 1 PMID:2987059 -3.4.15.1 lvvypwtqry rattus norvegicus 230.0 83.0 4 PMID:14499287 -3.4.15.1 mca-rppgfsafk(dnp)-oh homo sapiens 20.33 20.33 1 PMID:24228790 -3.4.15.1 met5-enkephalin homo sapiens 58.3 58.3 1 PMID:2987059 -3.4.15.1 mkrsrgpsprr drosophila sp. (in: flies) 18.8 18.8 1 PMID:16403023 -3.4.15.1 n-(3-(2-furyl)acryloyl)-phe-ala-ala bos taurus 178.0 178.0 1 PMID:12935891 -3.4.15.1 n-(3-(2-furyl)acryloyl)-phe-ala-lys bos taurus 85.0 54.0 3 PMID:12935891 -3.4.15.1 n-(3-(2-furyl)acryloyl)-phe-ala-pro bos taurus 45.0 30.0 3 PMID:12935891 -3.4.15.1 n-(3-(2-furyl)acryloyl)-phe-gly-gly bos taurus 315.0 287.5 2 PMID:11403651;PMID:12935891 -3.4.15.1 n-(3-(2-furyl)acryloyl)-phe-phe-arg bos taurus 76.0 45.0 3 PMID:11403651;PMID:12935891 -3.4.15.1 n-(3-[2-furyl]acryloyl)-l-phenylalanylglycylglycine struthio camelus australis 987.3 987.3 1 * -3.4.15.1 n-benzyloxycarbonyl-l-phe-l-his-l-leu bos taurus 12.0 12.0 1 PMID:12935891 -3.4.15.1 n-hippuryl-his-leu bos taurus 6.5 6.5 1 PMID:11403651 -3.4.15.1 neurotensin homo sapiens 0.567 0.567 1 PMID:2987059 -3.4.15.1 o-aminobenzoyl-fdk-(dinitrophenyl)-p-oh homo sapiens 101.7 79.45 4 PMID:10913258 -3.4.15.1 o-aminobenzoyl-frk-(dinitrophenyl)-p-oh homo sapiens 69.2 54.9 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-gfspfaq-(n-2,4-dinitrophenyl)ethylenediamine homo sapiens 3.3 2.0 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-gfspfeq-(n-2,4-dinitrophenyl)ethylenediamine homo sapiens 2.2 2.2 1 PMID:10913258 -3.4.15.1 o-aminobenzoyl-gfspffq-(n-2,4-dinitrophenyl)ethylenediamine homo sapiens 12.6 10.1 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-gfspflq-(n-2,4-dinitrophenyl)ethylenediamine homo sapiens 4.8 3.7 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-gfspfqq-(n-2,4-dinitrophenyl)ethylenediamine homo sapiens 2.0 0.6 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-gfspfra-(n-2,4-dinitrophenyl)ethylenediamine homo sapiens 10.4 5.0 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-gfspfrf-(n-2,4-dinitrophenyl)ethylenediamine homo sapiens 4.2 1.4 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-gfspfri-(n-2,4-dinitrophenyl)ethylenediamine homo sapiens 8.7 2.9 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-gfspfrn-(n-2,4-dinitrophenyl)ethylenediamine homo sapiens 3.8 3.3 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-gfspfrq-(n-2,4-dinitrophenyl)ethylenediamine homo sapiens 4.2 2.7 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-gfspfrr-(n-2,4-dinitrophenyl)ethylenediamine homo sapiens 1.4 1.0 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-gfspfrs-(n-2,4-dinitrophenyl)ethylenediamine homo sapiens 2.4 1.3 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-gfspfsq-(n-2,4-dinitrophenyl)ethylenediamine homo sapiens 2.3 2.0 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-sdk-(dinitrophenyl)-p-oh homo sapiens 44.2 24.6 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-srk-(dinitrophenyl)-p-oh homo sapiens 28.6 21.15 2 PMID:10913258 -3.4.15.1 o-aminobenzoyl-tdk-(dinitrophenyl)-p-oh homo sapiens 36.3 9.9 4 PMID:10913258 -3.4.15.1 o-aminobenzoyl-trk-(dinitrophenyl)-p-oh homo sapiens 82.0 13.9 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-ydk-(dinitrophenyl)-p-oh homo sapiens 62.5 28.9 3 PMID:10913258 -3.4.15.1 o-aminobenzoyl-yrk-(dinitrophenyl)-p-oh homo sapiens 85.6 58.8 3 PMID:10913258 -3.4.15.1 substance p homo sapiens 21.3 12.525 2 PMID:1848554;PMID:2987059 -3.4.15.1 toac1-angiotensin i oryctolagus cuniculus 5.83 5.83 1 PMID:17485083 -3.4.15.1 toac3-angiotensin i oryctolagus cuniculus 2.56 2.56 1 PMID:17485083 -3.4.15.5 o-aminobenzoyl-frak(2,4-dinitrophenyl)-oh escherichia coli 1.1 1.1 1 PMID:19558329 -3.4.15.5 o-aminobenzoyl-frk(2,4-dinitrophenyl)p-oh escherichia coli 0.81 0.81 1 PMID:19558329 -3.4.15.5 o-aminobenzoyl-lfk(2,4-dinitrophenyl)-oh escherichia coli 1.4 1.4 1 PMID:19558329 -3.4.15.6 [l-asp(4-arg)]n synechocystis sp. pcc 6803 16.5 16.5 1 PMID:19591842 -3.4.16.2 myoglobin penicillium janthinellum 1.1 0.7000000000000001 2 PMID:18211097;PMID:18264573 -3.4.16.4 (2r)-2-[[n-(phenylacetyl)glycyl]sulfanyl]propanoic acid streptomyces sp. r61 5.7 5.7 1 PMID:17059224 -3.4.16.4 2-(n-glycyl-l-cysteinyl)acetyl-d-alanyl-d-alanine streptomyces sp. r61 0.17 0.17 1 PMID:15497971 -3.4.16.4 3-(n-acetyl-l-cysteinyl)propanoyl-d-alanyl-d-alanine streptomyces sp. r61 0.25 0.25 1 PMID:15497971 -3.4.16.4 3-(n-glycyl-cysteaminyl)propanoyl-d-alanyl-d-alanine streptomyces sp. r61 2.4 2.4 1 PMID:15497971 -3.4.16.4 3-(n-glycyl-l-cysteinyl)-propanoyl-d-alanyl-d-thiolactate streptomyces sp. r61 42.0 42.0 1 PMID:16042374 -3.4.16.4 3-(n-glycyl-l-cysteinyl)butanoyl-d-alanyl-d-alanine streptomyces sp. r61 0.27 0.27 1 PMID:15497971 -3.4.16.4 3-(n-glycyl-l-cysteinyl)propanoyl-d-alanyl-d-alanine streptomyces sp. r61 48.0 48.0 1 PMID:15497971 -3.4.16.4 3-[[n-(phenylacetyl)-d-alanyl]oxy]benzoic acid streptomyces sp. r61 31.0 31.0 1 PMID:17059224 -3.4.16.4 3-[[n-(phenylacetyl)glycyl]oxy]benzoic acid streptomyces sp. r61 1.51 1.51 1 PMID:17059224 -3.4.16.4 3-carboxyphenyl (2r)-n-(phenylacetyl)-2-hydroxyglycinate actinomadura sp. 10.4 10.4 1 PMID:22851054 -3.4.16.4 3-carboxyphenyl (2r)-n-(phenylacetyl)-2-hydroxyglycinate streptomyces sp. 6.9 6.9 1 PMID:22851054 -3.4.16.4 3-carboxyphenyl (2r)-n-(phenylacetyl)-2-methoxyglycinate actinomadura sp. 114.0 114.0 1 PMID:22851054 -3.4.16.4 3-carboxyphenyl (2r)-n-(phenylacetyl)-2-methoxyglycinate streptomyces sp. 4.0 4.0 1 PMID:22851054 -3.4.16.4 3-carboxyphenyl n-(phenylacetyl)-alpha-methoxyglycinate actinomadura sp. r39 114.0 114.0 1 PMID:16806948 -3.4.16.4 3-carboxyphenyl n-(phenylacetyl)-alpha-methoxyglycinate neisseria gonorrhoeae 106.0 106.0 1 PMID:16806948 -3.4.16.4 3-carboxyphenyl n-(phenylacetyl)-alpha-methoxyglycinate streptomyces sp. r61 44.0 44.0 1 PMID:16806948 -3.4.16.4 3-carboxyphenyl n-(phenylacetyl)-alpha-serinate actinomadura sp. r39 0.65 0.65 1 PMID:16806948 -3.4.16.4 3-carboxyphenyl n-(phenylacetyl)-alpha-serinate neisseria gonorrhoeae 22.0 22.0 1 PMID:16806948 -3.4.16.4 3-carboxyphenyl n-(phenylacetyl)-alpha-serinate streptomyces sp. r61 2.2 2.2 1 PMID:16806948 -3.4.16.4 acetyl-l-lys-d-ala-d-ala nonomuraea sp. 12.5 12.5 1 PMID:22788848 -3.4.16.4 benzoyl-d-ala-thioglycolate streptomyces sp. 0.11 0.11 1 PMID:12627955 -3.4.16.4 benzoyl-gly-thioglycolate streptomyces sp. 0.024 0.024 1 PMID:12627955 -3.4.16.4 benzoyl-gly-thiolactate streptomyces sp. 0.017 0.017 1 PMID:12627955 -3.4.16.4 d-ala-d-ala nonomuraea sp. 8.3 8.3 1 PMID:22788848 -3.4.16.4 diacetyl-l-lys-d-ala-d-ala streptomyces sp. 350.0 161.0 4 PMID:4464852;PMID:6597561;PMID:7238522 -3.4.16.4 gly-gamma-l-glu-d-ala-d-ala streptomyces sp. r61 12.8 12.8 1 PMID:11015198 -3.4.16.4 gly-l-alpha-amino-epsilon-pimelyl-d-ala-d-ala streptomyces sp. r61 69.0 69.0 1 PMID:11015198 -3.4.16.4 glycyl-l-alpha-amino-epsilon-pimelyl-d-alanyl-d-alanine streptomyces sp. r61 69.0 69.0 1 PMID:15497971 -3.4.16.4 glycyl-s-(3-[[(1r)-2-[[(1r)-1-carboxyethyl]amino]-1-methyl-2-oxoethyl]amino]-3-oxopropyl)-l-cysteine streptomyces sp. r61 48.0 48.0 1 PMID:17059224 -3.4.16.4 glycyl-s-(3-[[(1r)-2-[[(1r)-1-carboxyethyl]sulfanyl]-1-methyl-2-oxoethyl]amino]-3-oxopropyl)-l-cysteine streptomyces sp. r61 81.0 81.0 1 PMID:17059224 -3.4.16.4 l-ala-gamma-d-glu-l-lys-d-ala-d-ala escherichia coli 1.41 1.41 1 PMID:20015336 -3.4.16.4 l-ala-gamma-d-glu-l-lys-d-ala-d-ala mycolicibacterium smegmatis 1.0 1.0 1 PMID:32301689 -3.4.16.4 n,n'-diacetyl-l-lysyl-d-alanyl-d-alanine streptomyces sp. r61 34.5 34.5 1 PMID:17059224 -3.4.16.4 n-(n-acetyl-1-o-methyl-beta-muramoyl)-l-alanyl-d-gamma-glutamyl-l-lysyl-d-alanyl-d-alanine escherichia coli 0.9 0.9 1 PMID:14750804 -3.4.16.4 n-[(6s)-6-carboxy-6-(glycylamino)hexanoyl]-d-alanyl-d-alanine streptomyces sp. r61 69.0 69.0 1 PMID:17059224 -3.4.16.4 n-[n-acetyl-4-o-[2-(acetylamino)-2-deoxy-beta-d-glucopyranosyl]-1-o-methyl-beta-muramoyl]-l-alanyl-d-gamma-glutamyl-l-lysyl-d-alanyl-d-alanine escherichia coli 1.1 1.1 1 PMID:14750804 -3.4.16.4 n-acetylmuramoyl-l-alanyl-gamma-d-glutamyl-l-lysyl-d-alanyl-d-alanine escherichia coli k-12 3.13 3.13 1 PMID:19209901 -3.4.16.4 n-acetylmuramoyl-l-alanyl-gamma-d-glutamyl-meso-2,6-diaminopimelyl-d-alanyl-d-alanine escherichia coli k-12 3.47 3.47 1 PMID:19209901 -3.4.16.4 n-alpha-acetyl-l-lys-d-ala-thiolactate streptomyces sp. 0.1 0.1 1 PMID:12627955 -3.4.16.4 nalpha,nalpha-diacetyl-l-lys-d-ala-d-ala mycolicibacterium smegmatis 0.58 0.58 1 PMID:32301689 -3.4.16.4 nalpha,nepsilon-diacetyl-l-lys-d-ala-d-ala escherichia coli 2.7 1.6300000000000001 2 PMID:20015336 -3.4.16.4 nalpha,nepsilon-diacetyl-l-lys-d-ala-d-ala streptomyces sp. 0.3 0.3 1 PMID:12627955 -3.4.16.4 nalpha,nepsilon-diacetyl-l-lys-d-ala-thiolactate streptomyces sp. 0.43 0.43 1 PMID:12627955 -3.4.16.4 nalpha-acetyl-l-lys-d-ala-d-ala streptomyces sp. 0.45 0.45 1 PMID:12627955 -3.4.16.4 phenylacetyl-d-ala-thioglycolate streptomyces sp. 0.5 0.5 1 PMID:12627955 -3.4.16.4 phenylacetyl-d-ala-thiolactate streptomyces sp. 0.6 0.6 1 PMID:12627955 -3.4.16.5 9-(r)-4'-(r)-[[[(s)-1-[(ethoxycarbonyl)ethyl]amino]phenoxyphosphinyl]methoxy]-2'-fluoro-1'-furanyladenine homo sapiens 237.0 237.0 1 PMID:17145787 -3.4.16.5 9-[(r)-2-[[(s)-[[(s)-1-(isopropoxycarbonyl)ethyl]amino]phenoxyphosphinyl]methoxy]-propyl]adenine homo sapiens 1777.0 1777.0 1 PMID:17145787 -3.4.16.5 9-fluorenylmethoxycarbonyl-glu-glu-ala saccharomyces cerevisiae 6.7 4.8 4 PMID:11791720 -3.4.16.5 9-fluorenylmethoxycarbonyl-glu-glu-glu-ala saccharomyces cerevisiae 3.8 3.0 2 PMID:11791720 -3.4.16.5 9-fluorenylmethoxycarbonyl-glu-glu-glu-glu-ala saccharomyces cerevisiae 3.9 3.2 2 PMID:11791720 -3.4.16.5 9-fluorenylmethoxycarbonyl-glu-glu-glu-glu-glu-ala saccharomyces cerevisiae 3.7 3.0 2 PMID:11791720 -3.4.16.5 9-fluorenylmethoxycarbonyl-glu-glu-glu-glu-glu-glu-ala saccharomyces cerevisiae 3.5 2.9 2 PMID:11791720 -3.4.16.5 acetyl-phe ethyl ester saccharomyces cerevisiae 122.0 121.0 2 PMID:13269;PMID:237004 -3.4.16.5 acetyl-phe-leu saccharomyces cerevisiae 36.1 36.1 1 PMID:237004 -3.4.16.5 acetyl-tyr ethyl ester saccharomyces cerevisiae 105.0 105.0 1 PMID:237004 -3.4.16.5 benzoyl-ala benzyl ester saccharomyces cerevisiae 123.0 123.0 1 * -3.4.16.5 benzoyl-ala-ogly saccharomyces cerevisiae 58.3 58.3 1 * -3.4.16.5 benzoyl-ala-ome saccharomyces cerevisiae 51.7 51.7 1 * -3.4.16.5 benzoyl-gly benzyl ester saccharomyces cerevisiae 18.3 18.3 1 * -3.4.16.5 benzoyl-gly-arg saccharomyces cerevisiae 1.44 1.44 1 PMID:237004 -3.4.16.5 benzoyl-gly-beta-phenyllactate saccharomyces cerevisiae 21.2 21.2 1 PMID:237004 -3.4.16.5 benzoyl-gly-oet saccharomyces cerevisiae 2.5 2.5 1 * -3.4.16.5 benzoyl-gly-ogly saccharomyces cerevisiae 30.0 30.0 1 * -3.4.16.5 benzoyl-gly-ome saccharomyces cerevisiae 2.5 2.5 1 * -3.4.16.5 benzoyl-gly-ophe saccharomyces cerevisiae 18.3 18.3 1 * -3.4.16.5 benzoyl-gly-phe saccharomyces cerevisiae 3.83 3.815 2 PMID:237004 -3.4.16.5 benzoyl-phe-gly saccharomyces cerevisiae 11.5 11.5 1 * -3.4.16.5 benzoyl-phe-ogly saccharomyces cerevisiae 35.0 35.0 1 * -3.4.16.5 benzoyl-phe-ome saccharomyces cerevisiae 152.0 152.0 1 * -3.4.16.5 benzoyl-tyr-4-nitroanilide saccharomyces cerevisiae 2.1 2.1 1 PMID:13269 -3.4.16.5 benzyloxycarbonyl-ala-ala saccharomyces cerevisiae 69.4 69.4 1 PMID:237004 -3.4.16.5 benzyloxycarbonyl-ala-leu saccharomyces cerevisiae 465.0 465.0 1 PMID:13269 -3.4.16.5 benzyloxycarbonyl-ala-phe saccharomyces cerevisiae 150.0 150.0 1 PMID:12084062 -3.4.16.5 benzyloxycarbonyl-glu-phe saccharomyces cerevisiae 16.8 15.5 3 PMID:237004 -3.4.16.5 benzyloxycarbonyl-glu-tyr saccharomyces cerevisiae 23.8 19.0 3 PMID:237004 -3.4.16.5 benzyloxycarbonyl-gly-glu saccharomyces cerevisiae 0.46 0.39 2 PMID:237004 -3.4.16.5 benzyloxycarbonyl-gly-gly saccharomyces cerevisiae 2.18 2.18 1 PMID:237004 -3.4.16.5 benzyloxycarbonyl-gly-leu saccharomyces cerevisiae 3.2 3.2 1 PMID:12084062 -3.4.16.5 benzyloxycarbonyl-gly-phe saccharomyces cerevisiae 2.2 1.58 2 PMID:12084062;PMID:237004 -3.4.16.5 benzyloxycarbonyl-his-phe saccharomyces cerevisiae 2.05 1.82 3 PMID:237004 -3.4.16.5 benzyloxycarbonyl-his-tyr saccharomyces cerevisiae 10.7 9.45 2 PMID:237004 -3.4.16.5 benzyloxycarbonyl-leu-leu saccharomyces cerevisiae 6.85 6.85 1 PMID:237004 -3.4.16.5 benzyloxycarbonyl-leu-phe saccharomyces cerevisiae 46.0 46.0 1 PMID:237004 -3.4.16.5 benzyloxycarbonyl-phe-ala saccharomyces cerevisiae 120.0 120.0 1 PMID:237004 -3.4.16.5 benzyloxycarbonyl-phe-beta-ala saccharomyces cerevisiae 66.0 66.0 1 PMID:237004 -3.4.16.5 benzyloxycarbonyl-phe-glu saccharomyces cerevisiae 96.5 26.2 3 PMID:237004 -3.4.16.5 benzyloxycarbonyl-phe-gly saccharomyces cerevisiae 140.0 140.0 1 PMID:237004 -3.4.16.5 benzyloxycarbonyl-phe-his saccharomyces cerevisiae 11.6 7.3 2 PMID:237004 -3.4.16.5 benzyloxycarbonyl-phe-leu saccharomyces cerevisiae 130.0 92.0 3 PMID:12084062;PMID:13269;PMID:237004 -3.4.16.5 benzyloxycarbonyl-phe-nh2 saccharomyces cerevisiae 5.33 4.05 4 PMID:13269;PMID:237004 -3.4.16.5 benzyloxycarbonyl-phe-phe saccharomyces cerevisiae 420.0 420.0 1 PMID:237004 -3.4.16.5 benzyloxycarbonyl-phe-pro saccharomyces cerevisiae 23.0 23.0 1 PMID:237004 -3.4.16.5 benzyloxycarbonyl-tyr-glu monascus pilosus 2039.0 1381.0 2 PMID:15592905 -3.4.16.5 benzyloxycarbonyl-tyr-glu monascus purpureus 291.0 291.0 1 PMID:14749965 -3.4.16.5 cbz-phe-leu homo sapiens 12.1 12.1 1 PMID:24599961 -3.4.16.5 endothelin saccharomyces cerevisiae 24.2 24.2 1 PMID:927202 -3.4.16.5 furylacryloyl-phe ethyl ester saccharomyces cerevisiae 68.3 68.3 1 PMID:8679540 -3.4.16.5 furylacryloyl-phe-ala saccharomyces cerevisiae 162.0 162.0 1 * -3.4.16.5 furylacryloyl-phe-gly saccharomyces cerevisiae 96.7 96.7 1 * -3.4.16.5 furylacryloyl-phe-leu saccharomyces cerevisiae 81.7 81.7 1 * -3.4.16.5 furylacryloyl-phe-ogly-oh saccharomyces cerevisiae 61.7 42.95 2 PMID:8679540 -3.4.16.5 furylacryloyl-phe-ome saccharomyces cerevisiae 183.0 183.0 1 * -3.4.16.5 furylacryloyl-phe-val saccharomyces cerevisiae 108.0 108.0 1 * -3.4.16.5 hippuryl-beta-phenyl lactate saccharomyces cerevisiae 21.2 21.2 1 PMID:13269 -3.4.16.6 dansyl-phe-ala-arg drosophila melanogaster 32.6 18.23 2 PMID:12393882 -3.4.17.1 (ala)4 bos taurus 100.0 100.0 1 * -3.4.17.1 (s)-hippuryl-alpha-mephe bos taurus 0.33 0.33 1 PMID:10819170 -3.4.17.1 (s)-hippuryl-alpha-methylphenyllactic acid bos taurus 477.0 477.0 1 PMID:10819170 -3.4.17.1 (s)-hippuryl-ophe bos taurus 682.0 682.0 1 PMID:10819170 -3.4.17.1 3-(2-furyl)acryloyl-l-phe-l-ala homo sapiens 24.3 24.3 1 PMID:20385563 -3.4.17.1 3-(2-furyl)acryloyl-l-phe-l-ile homo sapiens 12.4 12.4 1 PMID:20385563 -3.4.17.1 3-(2-furyl)acryloyl-l-phe-l-leu homo sapiens 13.4 13.4 1 PMID:20385563 -3.4.17.1 3-(2-furyl)acryloyl-l-phe-l-met homo sapiens 23.9 23.9 1 PMID:20385563 -3.4.17.1 3-(2-furyl)acryloyl-l-phe-l-phe homo sapiens 44.3 44.3 1 PMID:20385563 -3.4.17.1 3-(2-furyl)acryloyl-l-phe-l-trp homo sapiens 57.3 57.3 1 PMID:20385563 -3.4.17.1 3-(2-furyl)acryloyl-l-phe-l-val homo sapiens 19.4 19.4 1 PMID:20385563 -3.4.17.1 5-dimethyl-aminonaphthalene-1-sulfonyl-ala-ala-l-beta-phenyllactate bos taurus 0.062 0.062 1 PMID:6591178 -3.4.17.1 5-dimethyl-aminonaphthalene-1-sulfonyl-ala-ala-phe bos taurus 1.18 1.18 1 PMID:6591178 -3.4.17.1 angiotensin i homo sapiens 8.23 8.23 1 PMID:20385563 -3.4.17.1 benzoyl-gly-gly-l-alpha-hydroxy-beta-phenyllactate homo sapiens 767.0 767.0 1 PMID:938622 -3.4.17.1 benzoyl-gly-gly-l-phe bos taurus 20.0 20.0 1 * -3.4.17.1 benzoyl-gly-gly-l-phe homo sapiens 13.3 13.3 1 PMID:938622 -3.4.17.1 benzoyl-gly-l-alpha-hydroxy-beta-phenyllactate homo sapiens 505.0 505.0 1 PMID:938622 -3.4.17.1 benzoyl-gly-l-phe bos taurus 183.0 183.0 1 * -3.4.17.1 benzoyl-gly-l-phe homo sapiens 66.7 39.2 2 PMID:938622 -3.4.17.1 benzoyl-gly-l-phe rattus norvegicus 16.0 16.0 1 PMID:7371832 -3.4.17.1 benzoyl-gly-phenyllactate bos taurus 583.0 583.0 1 * -3.4.17.1 benzyloxycarbonyl-ala-phe rattus norvegicus 89.0 89.0 1 PMID:7371832 -3.4.17.1 benzyloxycarbonyl-gly-phe rattus norvegicus 4.2 4.2 1 PMID:7371832 -3.4.17.1 benzyloxycarbonyl-phe-leu rattus norvegicus 66.0 66.0 1 PMID:7371832 -3.4.17.1 carbobenzoxy-gly-gly-l-tyr bos taurus 85.0 85.0 1 * -3.4.17.1 carbobenzoxy-gly-gly-leu struthio camelus 5.02 5.02 1 PMID:8013741 -3.4.17.1 carbobenzoxy-gly-gly-phe struthio camelus 11.9 11.9 1 PMID:8013741 -3.4.17.1 carbobenzoxy-gly-gly-val struthio camelus 6.13 6.13 1 PMID:8013741 -3.4.17.1 carbobenzoxy-gly-l-leu sus scrofa 29.0 29.0 1 PMID:14086721 -3.4.17.1 carbobenzoxy-gly-l-phe bos taurus 200.0 199.0 2 * -3.4.17.1 carbobenzoxy-gly-l-phe homo sapiens 112.0 80.15 2 PMID:938622 -3.4.17.1 carbobenzoxy-gly-l-phe squalus acanthias 14.7 14.7 1 PMID:5529813 -3.4.17.1 carbobenzoxy-gly-l-phe sus scrofa 139.0 139.0 1 PMID:14086721 -3.4.17.1 carbobenzoxy-gly-l-trp bos taurus 90.5 90.5 1 * -3.4.17.1 carbobenzoxy-gly-l-trp sus scrofa 29.8 29.8 1 PMID:14086721 -3.4.17.1 carbobenzoxy-gly-leu struthio camelus 1.28 1.28 1 PMID:8013741 -3.4.17.1 carbobenzoxy-gly-phe struthio camelus 5.85 5.85 1 PMID:8013741 -3.4.17.1 cinnamoyl-l-phenyllactate bos taurus 76.7 76.7 1 * -3.4.17.1 gly-l-tyr bos taurus 0.015 0.015 1 * -3.4.17.1 hippuryl-dl-beta-phenyllactate bos taurus 0.1 0.1 1 PMID:11513597 -3.4.17.1 hippuryl-dl-phenyllactate struthio camelus 0.081 0.081 1 PMID:8013741 -3.4.17.1 hippuryl-dl-phenyllactic acid squalus acanthias 635.0 635.0 1 PMID:5529813 -3.4.17.1 hippuryl-l-phe bos taurus 17.7 6.08 3 PMID:11513597;PMID:19552427 -3.4.17.1 hippuryl-l-phe rattus norvegicus 40.0 40.0 1 PMID:7018567 -3.4.17.1 hippuryl-l-phenylalanine bos taurus 4950.0 3050.0 8 PMID:30667288;PMID:31751718 -3.4.17.1 hippuryl-l-phenylalanine homo sapiens 4.3 4.3 1 PMID:8806703 -3.4.17.1 hippuryl-l-phenyllactate rattus norvegicus 933.0 693.5 2 PMID:7018567;PMID:7371832 -3.4.17.1 hippuryl-l-phenyllactate sus scrofa 1000.0 1000.0 1 PMID:14086721 -3.4.17.1 hippuryl-phe bos taurus 81.0 81.0 1 PMID:10819170 -3.4.17.1 hippuryl-phe struthio camelus 5.98 5.98 1 PMID:8013741 -3.4.17.1 l-beta-phenyllactate-alpha-((2-naphthoyl)amino)-cinnamoyl ester bos taurus 0.276 0.276 1 * -3.4.17.1 l-beta-phenyllactate-alpha-(acetylamino)-cinnamoyl ester bos taurus 0.725 0.725 1 * -3.4.17.1 l-beta-phenyllactate-alpha-(benzoylylamino)-cinnamoyl ester bos taurus 0.46 0.46 1 * -3.4.17.1 leu-enkephalin homo sapiens 2.33 2.33 1 PMID:20385563 -3.4.17.1 met-enkephalin homo sapiens 3.43 3.43 1 PMID:20385563 -3.4.17.1 met-enkephalin-l-arg-l-phe homo sapiens 1.45 1.45 1 PMID:20385563 -3.4.17.1 methotrexate-alpha-(1-naphthyl)alanine homo sapiens 0.09 0.09 1 PMID:8806703 -3.4.17.1 methotrexate-alpha-phenylalanine homo sapiens 1.9 1.9 1 PMID:8806703 -3.4.17.1 n-(2-furanacryloyl)-phe-phe bos taurus 667.0 667.0 1 * -3.4.17.1 n-(3-[2-furyl]acryloyl)-phe-phe trypanosoma cruzi 11.0 9.3 2 PMID:17007610 -3.4.17.1 n-[3-(2-furyl)acryloyl]-phe-phe bos taurus 0.05 0.05 1 PMID:11513597 -3.4.17.1 n-acetyl-gly-l-phenyllactic acid squalus acanthias 86.0 86.0 1 PMID:5529813 -3.4.17.1 n-carbobenzoxy-gly-gly-l-leu rattus norvegicus 199.0 106.5 2 PMID:3182871 -3.4.17.1 n-carbobenzoxy-gly-gly-l-phe rattus norvegicus 97.0 77.0 2 PMID:3182871 -3.4.17.1 n-carbobenzoxy-gly-l-phe rattus norvegicus 22.4 19.6 2 PMID:3182871 -3.4.17.1 n-carbobenzoxy-gly-l-tyr rattus norvegicus 26.2 20.3 2 PMID:3182871 -3.4.17.1 neurotensin homo sapiens 0.24 0.24 1 PMID:20385563 -3.4.17.1 o-(trans-p-chlorocinnamoyl)-l-beta-phenyllactate bos taurus 0.11 0.11 1 PMID:11513597 -3.4.17.1 ochratoxin a homo sapiens 0.101 0.101 1 PMID:37330104 -3.4.17.1 p-nitrophenyl acetate homo sapiens 0.042 0.042 1 PMID:16522806 -3.4.17.10 dansyl-phe-ala-arg sus scrofa 13.0 13.0 1 PMID:2321755 -3.4.17.10 hippuryl-arg sus scrofa 8.5 8.5 1 PMID:2321755 -3.4.17.10 iodo-acetyl-tyr-ala-arg sus scrofa 16.0 16.0 1 PMID:2321755 -3.4.17.11 (2-chloroethyl)-(2-(methylsulfoyloxyethyl)amino)aminobenzyl-l-glutamic acid pseudomonas sp. 583.0 583.0 1 PMID:16078849 -3.4.17.11 (4-[bis(2-bromoethyl)amino]-2,3,5-trifluorobenzoyl)-l-glutamic acid pseudomonas sp. 825.0 825.0 1 PMID:16078849 -3.4.17.11 (4-[bis(2-bromoethyl)amino]-3,5-difluorobenzoyl)-l-glutamic acid pseudomonas sp. 827.0 827.0 1 PMID:16078849 -3.4.17.11 (4-[bis(2-chloroethyl)amino]-2,3,5-trifluorobenzoyl)-l-glutamic acid pseudomonas sp. 1150.0 1150.0 1 PMID:16078849 -3.4.17.11 (4-[bis(2-chloroethyl)amino]-3,5-difluorobenzoyl)-l-glutamic acid pseudomonas sp. 732.0 732.0 1 PMID:16078849 -3.4.17.11 (4-[bis(2-iodoethyl)amino]-2,3,5-trifluorobenzoyl)-l-glutamic acid pseudomonas sp. 220.0 220.0 1 PMID:16078849 -3.4.17.11 (4-[bis(2-iodoethyl)amino]-3,5-difluorobenzoyl)-l-glutamic acid pseudomonas sp. 1150.0 1150.0 1 PMID:16078849 -3.4.17.11 [4-[bis(2-chloroethyl)amino]-3,5-difluorobenzoyl]-l-glutamic acid homo sapiens 732.0 732.0 1 PMID:19259950 -3.4.17.11 [4-[bis(2-hydroxyethyl)amino]-3,5-difluorobenzoyl]-l-glutamic acid homo sapiens 747.0 747.0 1 PMID:19259950 -3.4.17.11 diallyl 4-[[2'-[n,n-bis(2''-chloroethyl)amino]phenyl]carbamoyloxymethyl]phenylcarbamoyl-l-glutamic acid pseudomonas sp. 2.9 2.9 1 PMID:12699387 -3.4.17.11 diallyl 4-[n-[4'-bis(2''-chloroethyl)aminophenyl]-n-methylcarbamoyloxymethyl]phenylcarbamoyl-l-glutamic acid pseudomonas sp. 5.5 5.5 1 PMID:12699387 -3.4.17.11 folate cohnella sp. a01 0.877 0.877 1 PMID:36493965 -3.4.17.11 methotrexate pseudomonas sp. 10.0 10.0 1 PMID:37602700 -3.4.17.11 methotrexate pseudomonas sp. rs-16 24.83 24.83 1 PMID:30970523 -3.4.17.11 methotrexate pseudomonas sp. rs16 4.57 4.57 1 PMID:33832417 -3.4.17.12 ala-ser-his-leu-gly-leu-ala-arg homo sapiens 7.4 7.4 1 PMID:17208058 -3.4.17.12 benzoyl-ala-arg homo sapiens 107.0 88.0 3 PMID:17208058 -3.4.17.12 benzoyl-asn-arg homo sapiens 35.0 35.0 1 PMID:17208058 -3.4.17.12 benzoyl-gln-arg homo sapiens 22.0 22.0 1 PMID:17208058 -3.4.17.12 benzoyl-gly-arg homo sapiens 6.07 5.7 3 PMID:17208058 -3.4.17.12 benzoyl-gly-argininic acid homo sapiens 316.0 294.5 2 PMID:17208058 -3.4.17.12 benzoyl-gly-lys homo sapiens 11.0 10.3 2 PMID:17208058 -3.4.17.12 benzoyl-his-arg homo sapiens 14.0 14.0 1 PMID:17208058 -3.4.17.12 benzoyl-ile-arg homo sapiens 1.0 1.0 1 PMID:17208058 -3.4.17.12 benzoyl-leu-arg homo sapiens 19.0 19.0 1 PMID:17208058 -3.4.17.12 benzoyl-met-arg homo sapiens 130.0 112.0 3 PMID:17208058 -3.4.17.12 benzoyl-phe-arg homo sapiens 33.0 33.0 1 PMID:17208058 -3.4.17.12 benzoyl-ser-arg homo sapiens 60.0 60.0 1 PMID:17208058 -3.4.17.12 benzoyl-thr-arg homo sapiens 22.9 22.9 1 PMID:17208058 -3.4.17.12 benzoyl-trp-arg homo sapiens 23.0 23.0 1 PMID:17208058 -3.4.17.12 benzoyl-tyr-arg homo sapiens 27.0 27.0 1 PMID:17208058 -3.4.17.12 benzoyl-val-arg homo sapiens 7.7 7.7 1 PMID:17208058 -3.4.17.12 bradykinin homo sapiens 2.45 2.45 1 PMID:18187413 -3.4.17.12 bradykinin(-phe-arg) homo sapiens 30.0 30.0 1 PMID:17208058 -3.4.17.12 dansyl-ala-arg homo sapiens 17.6 17.0 3 PMID:12457462;PMID:17208058 -3.4.17.12 furylacryloyl-ala-arg homo sapiens 40.0 36.0 2 PMID:17208058 -3.4.17.12 furylacryloyl-ala-lys homo sapiens 11.0 11.0 1 PMID:17208058 -3.4.17.12 gly-gly-arg homo sapiens 1.9 1.9 1 PMID:17208058 -3.4.17.12 gly-leu-ala-arg homo sapiens 8.2 8.2 1 PMID:17208058 -3.4.17.12 his-leu-gly-leu-ala-arg homo sapiens 6.6 6.6 1 PMID:17208058 -3.4.17.12 leu-ala-arg homo sapiens 4.2 4.2 1 PMID:17208058 -3.4.17.12 leu-gly-leu-ala-arg homo sapiens 6.1 6.1 1 PMID:17208058 -3.4.17.12 leu5-arg6-enkephalin homo sapiens 1.77 1.77 1 PMID:2914904;PMID:7674953 -3.4.17.12 met5-arg6-enkephalin homo sapiens 15.6 15.6 1 PMID:2914904;PMID:7674953 -3.4.17.12 met5-lys6-enkephalin homo sapiens 11.1 11.1 1 PMID:2914904;PMID:7674953 -3.4.17.12 n-(4-hydroxybenzoyl)-gly-arg homo sapiens 5.7 5.300000000000001 2 PMID:17208058 -3.4.17.12 pro-gly-lys-ala-arg homo sapiens 11.0 11.0 1 PMID:17208058 -3.4.17.12 ser-his-leu-gly-leu-ala-arg homo sapiens 6.7 6.7 1 PMID:17208058 -3.4.17.13 l-ala-gamma-d-glu-meso-diaminopimelyl-d-ala novosphingobium aromaticivorans 160.0 160.0 1 PMID:24123814 -3.4.17.14 d-ala-d-ala enterococcus faecalis 43.8 27.65 2 PMID:31071297 -3.4.17.15 benzyloxycarbonyl-gly-gly-leu homo sapiens 11.8 11.8 1 PMID:9450539 -3.4.17.15 benzyloxycarbonyl-gly-gly-leu rattus norvegicus 14.0 14.0 1 PMID:3182871 -3.4.17.15 benzyloxycarbonyl-gly-gly-phe homo sapiens 90.3 74.2 2 PMID:9450539 -3.4.17.15 benzyloxycarbonyl-gly-gly-trp rattus norvegicus 96.9 96.9 1 PMID:3182871 -3.4.17.15 benzyloxycarbonyl-gly-gly-tyr homo sapiens 70.0 70.0 1 PMID:9450539 -3.4.17.15 benzyloxycarbonyl-gly-phe homo sapiens 16.1 16.1 1 PMID:9450539 -3.4.17.15 benzyloxycarbonyl-gly-phe rattus norvegicus 16.8 16.8 1 PMID:3182871 -3.4.17.15 benzyloxycarbonyl-gly-trp rattus norvegicus 26.6 26.6 1 PMID:3182871 -3.4.17.15 benzyloxycarbonyl-gly-tyr homo sapiens 9.7 9.7 1 PMID:9450539 -3.4.17.15 benzyloxycarbonyl-gly-tyr rattus norvegicus 14.4 14.4 1 PMID:3182871 -3.4.17.15 hippuryl-l-phenylalanine homo sapiens 9.3 9.3 1 PMID:8806703 -3.4.17.15 methotrexate-alpha-(1-naphthyl)alanine homo sapiens 22.0 22.0 1 PMID:8806703 -3.4.17.15 methotrexate-alpha-phenylalanine homo sapiens 5.1 5.1 1 PMID:8806703 -3.4.17.16 benzyloxycarbonyl-pro-met sus scrofa 20.5 20.5 1 PMID:4038259 -3.4.17.16 myoglobin penicillium janthinellum 1.1 0.7000000000000001 2 PMID:18211097;PMID:18264573 -3.4.17.18 benzyloxycarbonyl-ala-ala-arg thermoactinomyces vulgaris 3.6 3.6 1 PMID:25619204 -3.4.17.18 benzyloxycarbonyl-ala-ala-leu thermoactinomyces vulgaris 4.7 4.7 1 PMID:25619204 -3.4.17.18 n-2,4-dinitrophenyl-ala-ala-arg thermoactinomyces vulgaris 15.0 14.8 2 PMID:18515300;PMID:18991561 -3.4.17.18 n-benzyloxycarbonyl-ala-ala-leu thermoactinomyces vulgaris 10.3 10.15 2 PMID:18515300;PMID:18991561 -3.4.17.18 n-benzyloxycarbonyl-l-ala-l-ala-l-arg thermoactinomyces vulgaris 14.7 14.7 1 PMID:33412495 -3.4.17.18 n-benzyloxycarbonyl-l-ala-l-ala-l-lys thermoactinomyces vulgaris 2.3 2.3 1 PMID:33412495 -3.4.17.18 n-carbobenzoxy-ala-ala-arg thermoactinomyces vulgaris 57.0 57.0 1 PMID:7674954 -3.4.17.18 n-carbobenzoxy-ala-ala-leu thermoactinomyces vulgaris 12.5 9.25 2 PMID:30878033;PMID:7674954 -3.4.17.18 n-carbobenzoxy-ala-ala-lys thermoactinomyces vulgaris 5.0 5.0 1 PMID:7674954 -3.4.17.18 n-carbobenzoxy-ala-ala-phe thermoactinomyces vulgaris 2.6 2.6 1 PMID:7674954 -3.4.17.18 n-carbobenzoxy-ala-ala-trp thermoactinomyces vulgaris 0.06 0.06 1 PMID:7674954 -3.4.17.19 n-(3-[2-furyl]acryloyl)-ala-lys trypanosoma cruzi 20.0 12.85 2 PMID:17007610 -3.4.17.19 n-(3-[2-furyl]acryloyl)-phe-phe trypanosoma cruzi 0.7 0.7 1 PMID:17007610 -3.4.17.2 benzoyl-gly-arg asterias amurensis 427.0 427.0 1 PMID:12381380 -3.4.17.2 benzoyl-gly-arg bos taurus 183.0 60.0 3 PMID:560863 -3.4.17.2 benzoyl-gly-gly-phe bos taurus 5.5 2.9165 2 PMID:560863 -3.4.17.2 benzoyl-gly-glycylphenyllactic acid bos taurus 917.0 459.915 2 PMID:560863 -3.4.17.2 benzoyl-gly-l-arg protopterus aethiopicus 86.0 86.0 1 PMID:5079891 -3.4.17.2 biotin-(epsilon-aminocaproic acid)2-glmvggvvr homo sapiens 1.9 1.9 1 PMID:12842119 -3.4.17.2 carbobenbenzoxy-gly-phe bos taurus 2.5 2.5 1 PMID:560863 -3.4.17.2 carbobenzoxy-gly-phe bos taurus 104.0 104.0 1 PMID:560863 -3.4.17.2 furylacryloyl-l-alanyl-l-arginine sus scrofa 50.0 50.0 1 PMID:8697097 -3.4.17.2 furylacryloyl-l-alanyl-l-lysine sus scrofa 38.6 38.6 1 PMID:8697097 -3.4.17.2 furylacryloylalanylarginine struthio camelus 58.7 58.7 1 PMID:8697097 -3.4.17.2 furylacryloylalanyllysine struthio camelus 24.6 24.6 1 PMID:8697097 -3.4.17.2 hippuryl-arg homo sapiens 61.0 61.0 1 PMID:9930672 -3.4.17.2 hippuryl-arg struthio camelus 86.9 86.9 1 PMID:8697097 -3.4.17.2 hippuryl-arg sus scrofa 119.0 119.0 1 PMID:8697097 -3.4.17.2 hippuryl-l-arg protopterus aethiopicus 171.0 171.0 1 PMID:5079891 -3.4.17.2 hippuryl-l-arg salaria basilisca 36.23 36.23 1 * -3.4.17.2 hippuryl-l-arg struthio camelus 27.4 27.4 1 PMID:8697097 -3.4.17.2 hippuryl-l-arg sus scrofa 48.3 48.3 1 PMID:8697097 -3.4.17.2 hippuryl-lys struthio camelus 10.5 10.5 1 PMID:8697097 -3.4.17.2 hippuryl-lys sus scrofa 25.5 25.5 1 PMID:8697097 -3.4.17.2 n-(phenylcarbonyl)glycyl-l-arginine bos taurus 0.667 0.667 1 PMID:560863 -3.4.17.2 n-benzoylglycyl-l-arg bos taurus 57.0 55.0 2 PMID:5140186 -3.4.17.20 anisylazoformyl-lys homo sapiens 29.5 27.0 5 PMID:11786552 -3.4.17.20 arg6-leu5-enkephalin homo sapiens 748.0 748.0 1 PMID:7727441 -3.4.17.20 arg6-met5-enkephalin homo sapiens 647.0 647.0 1 PMID:7727441 -3.4.17.20 biotinyl-(epsilon-aminocaproic acid)-(epsilon-aminocaproic acid)-gly-leu-met-val-gly-gly-val-val-arg-oh homo sapiens 2.3 2.3 1 PMID:12842119 -3.4.17.20 bradykinin homo sapiens 121.0 121.0 1 PMID:7727441 -3.4.17.20 hippuryl-arg bos taurus 2.74 2.74 1 PMID:18722183 -3.4.17.20 hippuryl-arg homo sapiens 2.67 2.67 1 PMID:18722183 -3.4.17.20 hippuryl-arginine homo sapiens 0.00042 0.00042 1 PMID:19335449 -3.4.17.20 hippuryl-l-arg homo sapiens 56.7 52.4 3 PMID:7727441;PMID:9442053 -3.4.17.20 hippuryl-l-argininic acid homo sapiens 169.0 169.0 1 PMID:7727441 -3.4.17.20 hippuryl-l-lys homo sapiens 45.6 40.7 3 PMID:7727441;PMID:9442053 -3.4.17.20 lys6-leu5-enkephalin homo sapiens 282.0 282.0 1 PMID:7727441 -3.4.17.20 lys6-met5-enkephalin homo sapiens 290.0 290.0 1 PMID:7727441 -3.4.17.20 n-[3-(2-furylacryloyl)]-l-ala-l-arg homo sapiens 36.0 36.0 1 PMID:7727441 -3.4.17.20 n-[3-(2-furylacryloyl)]-l-ala-l-lys homo sapiens 293.0 248.0 3 PMID:7727441;PMID:9442053 -3.4.17.20 n-benzoyl-2'-cyano-l-phe-l-arg homo sapiens 59.0 59.0 1 PMID:19732738 -3.4.17.20 n-benzoyl-gly-l-arg homo sapiens 64.0 64.0 1 PMID:19732738 -3.4.17.20 p-anisylazoformyl-l-arginine homo sapiens 0.315 0.315 1 PMID:19335449 -3.4.17.21 n-acetyl-asp-glu homo sapiens 4.0 4.0 1 PMID:12413472 -3.4.17.21 n-acetyl-l-aspartyl-l-glutamate homo sapiens 2.2 1.45 3 PMID:19301871;PMID:28904865;PMID:34978450 -3.4.17.21 n-acetyl-l-aspartyl-l-glutamate mus musculus 1.44 1.44 1 PMID:28904865 -3.4.17.21 pteroyl-di-l-glutamate homo sapiens 5.09 5.09 1 PMID:28904865 -3.4.17.21 pteroyl-di-l-glutamate mus musculus 3.63 3.63 1 PMID:28904865 -3.4.17.22 dansyl-leu-ala-arg bos taurus 25.0 25.0 1 PMID:7559630 -3.4.17.22 dansyl-leu-arg bos taurus 0.0417 0.0417 1 PMID:7559630 -3.4.17.22 dansyl-phe-ala-arg anas platyrhynchos 57.0 54.0 2 PMID:9525948 -3.4.17.22 dansyl-phe-ala-arg anas sp. 19.0 19.0 1 PMID:10506132 -3.4.17.22 dansyl-phe-ala-arg homo sapiens 12.5 12.5 2 PMID:29131831 -3.4.17.22 dansyl-phe-gly-arg anas sp. 2.6 2.6 1 PMID:10506132 -3.4.17.22 dansyl-phe-gly-arg bos taurus 4.4 4.4 1 PMID:7559630 -3.4.17.22 dansyl-phe-ile-arg bos taurus 0.07 0.07 1 PMID:7559630 -3.4.17.22 dansyl-phe-leu-arg bos taurus 4.5 4.5 1 PMID:7559630 -3.4.17.22 dansyl-phe-phe-arg anas platyrhynchos 17.0 11.45 2 PMID:9525948 -3.4.17.22 dansyl-phe-phe-arg anas sp. 3.7 3.7 1 PMID:10506132 -3.4.17.22 dansyl-phe-phe-arg bos taurus 5.9 5.9 1 PMID:7559630 -3.4.17.22 dansyl-phe-pro-arg bos taurus 0.002 0.002 1 PMID:7559630 -3.4.17.22 dansyl-pro-ala-arg anas platyrhynchos 22.0 22.0 1 PMID:9525948 -3.4.17.22 dansyl-pro-ala-arg anas sp. 6.7 6.7 1 PMID:10506132 -3.4.17.22 tyr-gly-gly-phe-leu-arg anas sp. 3.07 3.07 1 PMID:10506132 -3.4.17.22 tyr-gly-gly-phe-leu-lys anas sp. 3.97 3.97 1 PMID:10506132 -3.4.17.23 (7-methoxycoumarin-4-yl)acetyl-apk(2,4-dinitrophenyl)-oh homo sapiens 6840.0 6840.0 1 PMID:11815627 -3.4.17.23 angiotensin 3-8 homo sapiens 162.0 162.0 1 PMID:14609329 -3.4.17.23 angiotensin 4-8 homo sapiens 84.0 84.0 1 PMID:14609329 -3.4.17.23 angiotensin 5-8 homo sapiens 1518.0 1518.0 1 PMID:14609329 -3.4.17.23 angiotensin i homo sapiens 2.9 2.45 2 PMID:11815627;PMID:12358520;PMID:15283675 -3.4.17.23 angiotensin ii homo sapiens 1110.0 561.4 2 PMID:14609329;PMID:15283675 -3.4.17.24 biotin-glu-glu mus musculus 36.9 36.9 1 PMID:25416787 -3.4.17.24 biotin-glu-glu-glu mus musculus 257.6 257.6 1 PMID:25416787 -3.4.17.24 biotin-glu-glu-glu-gly-glu-glu mus musculus 94.7 94.7 1 PMID:25416787 -3.4.17.24 biotin-glu-glu-gly-glu-glu-glu mus musculus 195.1 195.1 1 PMID:25416787 -3.4.17.3 benzoyl-ala-arg homo sapiens 139.0 139.0 1 PMID:7457880 -3.4.17.3 benzoyl-ala-lys homo sapiens 352.0 352.0 1 PMID:7457880 -3.4.17.3 bradykinin homo sapiens 19.7 19.7 3 PMID:19010784 -3.4.17.3 c3a69-77 homo sapiens 57.9 8.4 3 PMID:19010784 -3.4.17.3 c5a66-74 homo sapiens 29.5 19.4 2 PMID:19010784 -3.4.17.3 chemerin homo sapiens 80.35 2.7 3 PMID:19010784 -3.4.17.3 fibrinopeptide alphaarg96-104 homo sapiens 2.9 2.2 2 PMID:19010784 -3.4.17.3 fibrinopeptide betalys125-133 homo sapiens 109.1 61.349999999999994 2 PMID:19010784 -3.4.17.3 fibrinopeptide gammalys54-62 homo sapiens 3.5 3.05 2 PMID:19010784 -3.4.17.3 fibrinopeptide gammalys77-85 homo sapiens 11.8 8.850000000000001 2 PMID:19010784 -3.4.17.3 fibrinopeptide-alpha-arg96-104 homo sapiens 1.5 1.5 1 PMID:19010784 -3.4.17.3 fibrinopeptide-beta-lys125-133 homo sapiens 13.6 13.6 1 PMID:19010784 -3.4.17.3 fibrinopeptide-gamma-lys54-62 homo sapiens 2.6 2.6 1 PMID:19010784 -3.4.17.3 fibrinopeptide-gamma-lys77-85 homo sapiens 5.9 5.9 1 PMID:19010784 -3.4.17.3 furylacryloyl-ala-arg homo sapiens 31.0 31.0 1 PMID:7457880 -3.4.17.3 furylacryloyl-l-ala-l-lys homo sapiens 97.0 97.0 1 PMID:7457880 -3.4.17.8 methyl n-acetylmuramate-l-ala-gamma-d-glu-meso-diaminopimelate-d-ala-d-ala pseudomonas aeruginosa 0.31 0.31 1 PMID:23629710 -3.4.17.8 nalpha,nepsilon-diacetyl-l-lys-d-ala-d-ala pseudomonas aeruginosa 0.59 0.59 1 PMID:23629710 -3.4.17.8 udp-n-acetylmuramoyl-l-alanyl-d-gamma-glutamyl-l-lysyl-d-alanyl-d-alanine enterococcus gallinarum 6.2 6.2 1 PMID:12047383 -3.4.18.1 (2,4-dinitrophenyl)-gffgw homo sapiens 0.007 0.007 1 PMID:10951198 -3.4.18.1 (2,4-dinitrophenyl)-gffrw homo sapiens 0.3 0.3 1 PMID:10951198 -3.4.18.1 (2,4-dinitrophenyl)-gffw homo sapiens 0.07 0.07 1 PMID:10951198 -3.4.18.1 (2,4-dinitrophenyl)-gfrfw homo sapiens 0.03 0.03 1 PMID:10951198 -3.4.18.1 (2,4-dinitrophenyl)-gfrw homo sapiens 0.7 0.7 1 PMID:10951198 -3.4.18.1 (2,4-dinitrophenyl)-grffw homo sapiens 0.23 0.23 1 PMID:10951198 -3.4.18.1 2-aminobenzoyl-arg-arg-(2,3-diaminopropionyl)-(2,4-dinitrophenyl)-pro + homo sapiens 0.06 0.06 1 PMID:10951198 -3.4.18.1 2-aminobenzoyl-leu-arg-(2,3-diaminopropionyl)-(2,4-dinitrophenyl)-pro + homo sapiens 0.02 0.02 1 PMID:10951198 -3.4.18.1 2-aminobenzoyl-phe-arg-(2,3-diaminopropionyl)-(2,4-dinitrophenyl)-pro + homo sapiens 0.07 0.07 1 PMID:10951198 -3.4.18.1 benzyloxycarbony-fr-4-methylcoumaryl-7-amide homo sapiens 0.22 0.22 1 PMID:10951198 -3.4.18.1 benzyloxycarbony-rr-4-methylcoumaryl-7-amide homo sapiens 6.08 3.355 2 PMID:10951198 -3.4.19.1 2-aminobenzoyl-ala-leu-phe-gln-gly-pro-phe(no2)-ala aeropyrum pernix 8.2 8.2 1 PMID:21084296 -3.4.19.1 ac-leu-p-nitroanilide aeropyrum pernix k1 36.4 10.6 3 PMID:18590836;PMID:18930847 -3.4.19.1 acetyl-ala-4-nitroanilide pyrococcus horikoshii 144.0 80.65 2 PMID:9651372 -3.4.19.1 acetyl-ala-4-nitroanilide trematomus bernacchii 1.7 0.857 2 PMID:24206103 -3.4.19.1 acetyl-ala-ala pyrococcus horikoshii 9900.0 5345.0 2 PMID:9651372 -3.4.19.1 acetyl-ala-ala-ala-ala pyrococcus horikoshii 2090.0 1185.5 2 PMID:9651372 -3.4.19.1 acetyl-leu-4-nitroanilide pyrococcus horikoshii 3200.0 1765.0 2 PMID:9651372 -3.4.19.1 acetyl-leu-4-nitroanilide trematomus bernacchii 0.09 0.09 1 PMID:24206103 -3.4.19.1 acetyl-met-7-amido-4-methylcoumarin trematomus bernacchii 7.74 3.8850000000000002 2 PMID:24206103 -3.4.19.1 ala-beta-naphthylamide streptomyces morookaense 8.79 8.79 1 PMID:16503293 -3.4.19.1 formylmethionine-beta-naphthylamide rattus norvegicus 76.4 76.4 1 PMID:1547272 -3.4.19.1 formylmethionine-leu rattus norvegicus 5.17 5.17 1 PMID:1547272 -3.4.19.1 formylmethionine-leu-phe rattus norvegicus 12.3 12.3 1 PMID:1547272 -3.4.19.1 formylmethionine-leu-tyr rattus norvegicus 15.5 15.5 1 PMID:1547272 -3.4.19.1 formylmethionine-phe rattus norvegicus 70.2 70.2 1 PMID:1547272 -3.4.19.1 formylmethionine-trp rattus norvegicus 31.3 31.3 1 PMID:1547272 -3.4.19.1 formylmethionine-val rattus norvegicus 5.94 5.94 1 PMID:1547272 -3.4.19.1 leu-beta-naphthylamide streptomyces morookaense 4.07 4.07 1 PMID:16503293 -3.4.19.1 n-acetyl-ala-p-nitroanilide sus scrofa 461.0 461.0 1 PMID:12206506 -3.4.19.1 n-acetyl-l-ala-4-nitroanilide saccharolobus solfataricus 17.5 17.5 1 PMID:22655081 -3.4.19.1 n-acetyl-l-alanyl 4-nitroanilide saccharolobus solfataricus 14.0 9.5 2 PMID:20941418;PMID:22655081 -3.4.19.1 n-acetyl-l-leu-4-nitroanilide saccharolobus solfataricus 18.0 18.0 1 PMID:22655081 -3.4.19.1 n-acetyl-l-leucyl 4-nitroanilide saccharolobus solfataricus 18.0 11.5 2 PMID:20941418;PMID:22655081 -3.4.19.1 n-acetyl-l-phe-4-nitroanilide saccharolobus solfataricus 2.0 2.0 1 PMID:22655081 -3.4.19.1 n-acetyl-l-phenylalanyl 4-nitroanilide saccharolobus solfataricus 8.0 8.0 1 PMID:22655081 -3.4.19.1 n-acetyl-leu-p-nitroanilide aeropyrum pernix 9.3 9.3 1 PMID:16670095 -3.4.19.1 n-acetyl-met-ala sus scrofa 33.0 31.0 2 PMID:9562627 -3.4.19.1 n-acetyl-met-leu rattus norvegicus 5.45 5.45 1 PMID:1547272 -3.4.19.1 n-acetyl-met-leu-phe rattus norvegicus 27.1 27.1 1 PMID:1547272 -3.4.19.1 n-acetyl-phe-2-naphthylamide aeropyrum pernix 4.28 4.28 1 PMID:21084296 -3.4.19.1 p-nitrophenyl caprylate aeropyrum pernix 6.6 6.6 1 PMID:16670095 -3.4.19.1 phe-beta-naphthylamide streptomyces morookaense 1.69 1.69 1 PMID:16503293 -3.4.19.1 pro-beta-naphthylamide streptomyces morookaense 1.61 1.61 1 PMID:16503293 -3.4.19.1 puromycin streptomyces morookaense 0.98 0.98 1 PMID:16503293 -3.4.19.1 tyr-beta-naphthylamide streptomyces morookaense 1.85 1.85 1 PMID:16503293 -3.4.19.12 dabcyl-fkkkgggdvke-edans porcine epidemic diarrhea virus 0.005 0.005 1 PMID:34643430 -3.4.19.12 dabcyl-frlkggapikgv-edans porcine epidemic diarrhea virus 0.00108 0.00108 1 PMID:34643430 -3.4.19.12 nedd8-7-amido-4-methylcoumarin oryza sativa 17.22 17.22 1 PMID:30498503 -3.4.19.12 ubiquitin 7-amido-4-methylcoumarin homo sapiens 33.67 18.6 3 PMID:22284438 -3.4.19.12 ubiquitin-7-amido-4-methylcoumarin homo sapiens 0.174 0.174 1 PMID:12705903 -3.4.19.12 ubiquitin-7-amido-4-methylcoumarin mus musculus 0.02 0.02 1 PMID:12913066 -3.4.19.12 ubiquitin-7-amido-4-methylcoumarin oryza sativa 7.46 7.46 1 PMID:30498503 -3.4.19.12 ubiquitin-7-amido-4-methylcoumarin synthetic construct 0.02 0.02 1 PMID:17144664 -3.4.19.12 ubiquitin-aw synthetic construct 0.0001 0.0001 1 PMID:17144664 -3.4.19.12 ubiquitin-rhodamine110-glycine homo sapiens 4.72 4.72 1 PMID:17869210 -3.4.19.12 ubiquitin-w synthetic construct 0.03 0.03 1 PMID:17144664 -3.4.19.12 ubiquitin-w-g75a synthetic construct 2.9 1.4549999999999998 2 PMID:17144664 -3.4.19.12 ubiquitin-w-g76a synthetic construct 1.7 0.85055 2 PMID:17144664 -3.4.19.12 ubiquitin-w-h68a synthetic construct 4.6 2.3299999999999996 2 PMID:17144664 -3.4.19.12 ubiquitin-w-i44a synthetic construct 1.6 0.8450000000000001 2 PMID:17144664 -3.4.19.12 ubiquitin-w-k11a synthetic construct 3.4 1.7149999999999999 2 PMID:17144664 -3.4.19.12 ubiquitin-w-k48a synthetic construct 2.4 1.22 2 PMID:17144664 -3.4.19.12 ubiquitin-w-k63a synthetic construct 2.4 1.2149999999999999 2 PMID:17144664 -3.4.19.12 ubiquitin-w-k6a synthetic construct 4.0 2.015 2 PMID:17144664 -3.4.19.12 ubiquitin-w-l71a synthetic construct 9.2 4.614999999999999 2 PMID:17144664 -3.4.19.12 ubiquitin-w-l73a synthetic construct 5.7 2.855 2 PMID:17144664 -3.4.19.12 ubiquitin-w-l8a synthetic construct 6.6 6.6 1 PMID:17144664 -3.4.19.12 ubiquitin-w-r42a synthetic construct 0.2 0.11 2 PMID:17144664 -3.4.19.12 ubiquitin-w-r72a synthetic construct 4.4 2.2150000000000003 2 PMID:17144664 -3.4.19.12 ubiquitin-w-r74a synthetic construct 0.3 0.155 2 PMID:17144664 -3.4.19.12 ubiquitin-w-v70a synthetic construct 6.7 3.375 2 PMID:17144664 -3.4.19.12 ubiquitin-wa synthetic construct 0.0005 0.0005 1 PMID:17144664 -3.4.19.12 ubiquitinyl-7-amido-4-methylcoumarin homo sapiens 0.001 0.001 1 PMID:16475834 -3.4.19.12 ubiquitinyl-7-amido-4-methylcoumarin mus musculus 0.02 0.02 1 PMID:12913066 -3.4.19.12 wild-type di-ubiquitin bos taurus 0.0728 0.0728 1 PMID:9353303 -3.4.19.13 glutathione arabidopsis thaliana 1.17 0.75 2 PMID:35932489 -3.4.19.13 l-glutamic acid-(4-nitroanilide) bacillus licheniformis 12.45 12.45 1 PMID:25218521 -3.4.19.3 4(r)-n-(2-nitroxyethyl)-2-oxothiazolidine-4-carboxamide homo sapiens 1.8 1.8 1 PMID:14709911 -3.4.19.3 4(r)-n-(2-nitroxyethyl)-2-oxothiazolidine-4-carboxamide mus musculus 2.3 2.3 1 PMID:14709911 -3.4.19.3 4(r)-n-(2-nitroxyethyl)-2-oxothiazolidine-4-carboxamide rattus norvegicus 2.3 2.3 1 PMID:14709911 -3.4.19.3 gonadotropin-releasing hormone trypanosoma brucei brucei 12.0 10.5 2 PMID:16248854 -3.4.19.3 l-2-oxoimidazolidine-4-carboxyl-l-ala homo sapiens 2.4 2.4 1 PMID:14709911 -3.4.19.3 l-2-oxoimidazolidine-4-carboxyl-l-ala mus musculus 2.7 2.7 1 PMID:14709911 -3.4.19.3 l-2-oxoimidazolidine-4-carboxyl-l-ala rattus norvegicus 3.6 3.6 1 PMID:14709911 -3.4.19.3 l-2-oxooxazolidine-4-carboxyl-aminoethylnitrate rattus norvegicus 7.6 7.6 1 PMID:14709911 -3.4.19.3 l-2-oxooxazolidine-4-carboxyl-l-ala homo sapiens 6.4 6.4 1 PMID:14709911 -3.4.19.3 l-2-oxooxazolidine-4-carboxyl-l-ala mus musculus 6.6 6.6 1 PMID:14709911 -3.4.19.3 l-2-oxooxazolidine-4-carboxyl-l-ala rattus norvegicus 8.1 8.1 1 PMID:14709911 -3.4.19.3 l-2-oxothiazolidine-4-carboxyl-d-2-aminopropylnitrate rattus norvegicus 1.5 1.5 1 PMID:14709911 -3.4.19.3 l-2-oxothiazolidine-4-carboxyl-ethanolamine rattus norvegicus 0.9 0.9 1 PMID:14709911 -3.4.19.3 l-2-oxothiazolidine-4-carboxyl-l-2-aminopropylnitrate rattus norvegicus 3.2 3.2 1 PMID:14709911 -3.4.19.3 l-2-oxothiazolidine-4-carboxyl-l-ala homo sapiens 2.3 2.3 1 PMID:14709911 -3.4.19.3 l-2-oxothiazolidine-4-carboxyl-l-ala mus musculus 2.5 2.5 1 PMID:14709911 -3.4.19.3 l-2-oxothiazolidine-4-carboxyl-l-ala rattus norvegicus 3.4 3.4 1 PMID:14709911 -3.4.19.3 l-pyroglutamyl-7-amido-4-methylcoumarin trypanosoma brucei brucei 58.0 52.5 2 PMID:16248854 -3.4.19.3 l-pyroglutamyl-aminoethylnitrate rattus norvegicus 3.5 3.5 1 PMID:14709911 -3.4.19.3 l-pyroglutamyl-beta-naphthylamide bacillus amyloliquefaciens 785.0 552.0 2 PMID:11359794;PMID:11410277 -3.4.19.3 l-pyroglutamyl-l-ala homo sapiens 2.4 2.4 1 PMID:14709911 -3.4.19.3 l-pyroglutamyl-l-ala mus musculus 3.2 3.2 1 PMID:14709911 -3.4.19.3 l-pyroglutamyl-l-ala rattus norvegicus 3.7 3.7 1 PMID:14709911 -3.4.19.3 l-pyroglutamyl-p-nitroanilide trypanosoma brucei brucei 64.0 58.0 2 PMID:16248854 -3.4.19.3 luteinizing-hormone-releasing hormone bacillus amyloliquefaciens 7.2 7.2 1 * -3.4.19.3 neurotensin bacillus amyloliquefaciens 26.3 26.3 1 * -3.4.19.3 pyroglutamic acid-7-amido-4-methylcoumarin bos taurus 3.5 3.5 1 PMID:17119851 -3.4.19.3 pyroglutamyl-beta-naphthylamide pseudomonas fluorescens 31.4 31.4 1 PMID:8655512 -3.4.19.3 thyroliberin-releasing hormone bacillus amyloliquefaciens 21.0 21.0 1 * -3.4.19.3 thyrotrophin-releasing hormone trypanosoma brucei brucei 22.0 21.0 2 PMID:16248854 -3.4.19.5 alpha-asp-leu colwellia psychrerythraea 89.0 89.0 1 PMID:28723955 -3.4.19.5 alpha-asp-leu escherichia coli 15.7 15.7 1 PMID:15882050 -3.4.19.5 beta-asp-ala colwellia psychrerythraea 166.0 166.0 1 PMID:28723955 -3.4.19.5 beta-asp-ala escherichia coli 213.0 213.0 1 PMID:15882050 -3.4.19.5 beta-asp-gly colwellia psychrerythraea 181.0 181.0 1 PMID:28723955 -3.4.19.5 beta-asp-gly escherichia coli 0.93 0.93 1 PMID:15882050 -3.4.19.5 beta-asp-his colwellia psychrerythraea 74.0 74.0 1 PMID:28723955 -3.4.19.5 beta-asp-his escherichia coli 20.8 20.8 1 PMID:15882050 -3.4.19.5 beta-asp-leu colwellia psychrerythraea 164.0 164.0 1 PMID:28723955 -3.4.19.5 beta-asp-leu escherichia coli 104.0 34.0 5 PMID:15882050 -3.4.19.5 beta-asp-lys colwellia psychrerythraea 256.0 256.0 1 PMID:28723955 -3.4.19.5 beta-asp-lys escherichia coli 58.0 58.0 1 PMID:15882050 -3.4.19.5 beta-asp-phe cavia porcellus 1.98 1.98 1 PMID:24669941 -3.4.19.5 beta-asp-phe colwellia psychrerythraea 145.0 145.0 1 PMID:28723955 -3.4.19.5 beta-asp-phe escherichia coli 16.9 16.9 1 PMID:15882050 -3.4.19.5 beta-l-aspartyl-l-leucine lupinus luteus 0.813 0.813 1 PMID:15265041 -3.4.19.6 5-oxoprolyl 2-naphthylamide sus scrofa 0.6 0.6 1 PMID:7925352 -3.4.19.6 thyrotropin-releasing hormone sus scrofa 38.3 38.3 1 PMID:7925352 -3.4.19.7 acetyl-met-leu rattus norvegicus 5.45 5.45 1 PMID:1547272 -3.4.19.7 acetyl-met-leu-phe rattus norvegicus 27.1 27.1 1 PMID:1547272 -3.4.19.7 n-formyl-met 2-naphthylamide rattus norvegicus 230.0 153.2 2 PMID:1547272;PMID:7437450 -3.4.19.7 n-formyl-met-leu rattus norvegicus 5.17 5.17 1 PMID:1547272 -3.4.19.7 n-formyl-met-leu-phe rattus norvegicus 12.3 12.3 1 PMID:1547272 -3.4.19.7 n-formyl-met-leu-tyr rattus norvegicus 15.5 15.5 1 PMID:1547272 -3.4.19.7 n-formyl-met-phe rattus norvegicus 70.2 70.2 1 PMID:1547272 -3.4.19.7 n-formyl-met-trp rattus norvegicus 31.3 31.3 1 PMID:1547272 -3.4.19.7 n-formyl-met-val rattus norvegicus 5.94 5.94 1 PMID:1547272 -3.4.19.9 5-formyltetrahydrofolate triglutamate danio rerio 48.2 48.2 1 PMID:19005029 -3.4.19.9 folic acid pentaglutamate solanum lycopersicum 2.13 1.91 2 PMID:18757550 -3.4.19.9 p-aminobenzoylpentaglutamate arabidopsis thaliana 8.29 6.8999999999999995 2 PMID:15961386 -3.4.19.9 p-aminobenzoylpentaglutamate solanum lycopersicum 1.08 1.02 2 PMID:18757550 -3.4.19.9 pteroylpentaglutamate arabidopsis thaliana 19.46 5.355 4 PMID:15961386 -3.4.21.1 4-nitrophenyl acetate bos taurus 0.1 0.046 6 * -3.4.21.1 4-nitrophenyl benzoate bos taurus 0.047 0.017 7 * -3.4.21.1 acetyl-l-leu methyl ester bos taurus 6.6 6.6 1 PMID:9434749 -3.4.21.1 acetyl-l-trp ethyl ester bos taurus 48.4 48.4 1 PMID:9434749 -3.4.21.1 acetyl-leu methyl ester camelus bactrianus 22.1 22.1 1 PMID:9434749 -3.4.21.1 acetyl-phe ethyl ester bos taurus 52.4 52.4 1 PMID:9434749 -3.4.21.1 acetyl-phe ethyl ester camelus bactrianus 5.3 5.3 1 PMID:9434749 -3.4.21.1 acetyl-trp ethyl ester camelus bactrianus 9.3 9.3 1 PMID:9434749 -3.4.21.1 acetyl-tyr ethyl ester bos taurus 126.0 126.0 1 PMID:9434749 -3.4.21.1 acetyl-tyr ethyl ester camelus bactrianus 25.4 25.4 1 PMID:9434749 -3.4.21.1 ala-ala-phe-7-amido-4-methylcoumarin bos taurus 21.7 4.13 7 PMID:18572890;PMID:27522589 -3.4.21.1 benzoyl-4-guanidinophenyl ester bos taurus 0.13 0.13 1 PMID:10848965 -3.4.21.1 benzoyl-d-ala-4-guanidinophenyl ester bos taurus 6.08 3.3200000000000003 2 PMID:10848965 -3.4.21.1 benzoyl-d-leu-4-guanidinophenyl ester bos taurus 6.0 4.52 2 PMID:10848965 -3.4.21.1 benzoyl-d-phe-4-guanidinophenyl ester bos taurus 5.54 5.54 1 PMID:10848965 -3.4.21.1 benzoyl-gly-4-guanidinophenyl ester bos taurus 6.08 3.63 2 PMID:10848965 -3.4.21.1 benzoyl-l-ala-4-guanidinophenyl ester bos taurus 10.4 10.4 1 PMID:10848965 -3.4.21.1 benzoyl-tyr ethyl ester bos taurus 76.6 76.6 1 PMID:9434749 -3.4.21.1 benzoyl-tyr ethyl ester camelus bactrianus 57.5 57.5 1 PMID:9434749 -3.4.21.1 l-alanyl-l-alanyl-l-prolyl-l-phenylalanine p-nitroanilide homo sapiens 22.8 16.85 2 PMID:35934298 -3.4.21.1 n-acetyl-l-leucine methyl ester bos taurus 6.5 6.5 1 PMID:10724334 -3.4.21.1 n-acetyl-l-leucine methyl ester camelus dromedarius 4.6 4.6 1 PMID:10724334 -3.4.21.1 n-acetyl-l-phe-ala-thr-pal-5-amido-2-nitrobenzoic acid bos taurus 6.4 6.4 1 PMID:18336354 -3.4.21.1 n-acetyl-l-phe-ala-thr-phe-(p-cn)-5-amido-2-nitrobenzoic acid bos taurus 3.0 3.0 1 PMID:18336354 -3.4.21.1 n-acetyl-l-phe-ala-thr-phe-(p-coome)-5-amido-2-nitrobenzoic acid bos taurus 0.3 0.3 1 PMID:18336354 -3.4.21.1 n-acetyl-l-phe-ala-thr-phe-(p-guanidine)-5-amido-2-nitrobenzoic acid bos taurus 6.5 6.5 1 PMID:18336354 -3.4.21.1 n-acetyl-l-phe-ala-thr-phe-(p-nh2)-5-amido-2-nitrobenzoic acid bos taurus 16.2 16.2 1 PMID:18336354 -3.4.21.1 n-acetyl-l-phe-ala-thr-phe-(p-no2)-5-amido-2-nitrobenzoic acid bos taurus 0.6 0.6 1 PMID:18336354 -3.4.21.1 n-acetyl-l-phe-ala-thr-phe-5-amido-2-nitrobenzoic acid bos taurus 6.1 6.1 1 PMID:18336354 -3.4.21.1 n-acetyl-l-phe-ala-thr-tyr-5-amido-2-nitrobenzoic acid bos taurus 22.7 22.7 1 PMID:18336354 -3.4.21.1 n-acetyl-l-phenylalanine ethyl ester bos taurus 54.8 54.8 1 PMID:10724334 -3.4.21.1 n-acetyl-l-phenylalanine ethyl ester camelus dromedarius 40.3 40.3 1 PMID:10724334 -3.4.21.1 n-acetyl-l-tryptophan ethyl ester bos taurus 48.8 48.8 1 PMID:10724334 -3.4.21.1 n-acetyl-l-tryptophan ethyl ester camelus dromedarius 25.7 25.7 1 PMID:10724334 -3.4.21.1 n-acetyl-l-tyr-ethyl ester bos taurus 220.0 198.5 4 PMID:12387718 -3.4.21.1 n-acetyl-l-tyr-p-nitroanilide bos taurus 0.19 0.14500000000000002 2 PMID:12387718 -3.4.21.1 n-acetyl-l-tyrosine ethyl ester bos taurus 120.0 119.75 2 PMID:10724334 -3.4.21.1 n-acetyl-l-tyrosine ethyl ester camelus dromedarius 82.8 82.8 1 PMID:10724334 -3.4.21.1 n-alpha-benzoyl-dl-arginine-p-nitroanilide bos taurus 0.611 0.611 1 PMID:18598777 -3.4.21.1 n-benzoyl-l-tyr ethyl ester bos taurus 142.0 100.0 3 PMID:1764912 -3.4.21.1 n-benzoyl-l-tyr ethyl ester gadus morhua 329.0 210.5 6 PMID:1764912 -3.4.21.1 n-benzoyl-l-tyrosine 4-nitroanilide bos taurus 2.3 0.0475 4 PMID:23734596 -3.4.21.1 n-benzoyl-l-tyrosine ethyl ester bos taurus 70.4 4.035 6 PMID:10724334;PMID:11210116 -3.4.21.1 n-benzoyl-l-tyrosine ethyl ester camelus dromedarius 45.9 45.9 1 PMID:10724334 -3.4.21.1 n-benzoyl-l-tyrosine methyl ester bos taurus 10.8 2.94 3 PMID:11210116 -3.4.21.1 n-benzoyl-l-tyrosine-4-nitroanilide bos taurus 0.5 0.15 3 * -3.4.21.1 n-benzoyl-l-tyrosyl ethyl ester bos taurus 1034.98 172.34 3 PMID:37969053 -3.4.21.1 n-benzoyl-l-tyrosyl-ethyl ester bos taurus 0.00942 0.00942 1 PMID:30876904 -3.4.21.1 n-benzoyl-tyr p-nitroanilide bos taurus 0.41 0.3 3 PMID:1764912 -3.4.21.1 n-benzoyl-tyr p-nitroanilide gadus morhua 0.82 0.42 5 PMID:1764912 -3.4.21.1 n-benzyloxycarbonyl-l-phe-ala-thr-phe-(p-no2)-5-amido-2-nitrobenzoic acid bos taurus 1.8 1.8 1 PMID:18336354 -3.4.21.1 n-benzyloxycarbonyl-l-phe-ala-thr-tyr-5-amido-2-nitrobenzoic acid bos taurus 16.7 16.7 1 PMID:18336354 -3.4.21.1 n-glutaryl-l-phe-p-nitroanilide bos taurus 0.31 0.029500000000000002 6 PMID:11737204 -3.4.21.1 n-glutaryl-l-phenylalanine-4-nitroanilide bos taurus 0.0146 0.0146 1 * -3.4.21.1 n-succinyl-ala-ala-pro-arg-p-nitroanilide bos taurus 0.05 0.032 2 PMID:11342033 -3.4.21.1 n-succinyl-ala-ala-pro-leu-4-nitroanilide musca domestica 0.55 0.55 1 PMID:22808532 -3.4.21.1 n-succinyl-ala-ala-pro-leu-p-nitroanilide bos taurus 16.0 8.04 3 PMID:11342033 -3.4.21.1 n-succinyl-ala-ala-pro-lys-p-nitroanilide bos taurus 0.34 0.14300000000000002 6 PMID:11342033 -3.4.21.1 n-succinyl-ala-ala-pro-met-p-nitroanilide bos taurus 15.0 8.225 2 PMID:11342033 -3.4.21.1 n-succinyl-ala-ala-pro-nle-p-nitroanilide bos taurus 18.0 15.0 2 PMID:11342033 -3.4.21.1 n-succinyl-ala-ala-pro-nva-p-nitroanilide bos taurus 9.31 4.3100000000000005 4 PMID:11342033 -3.4.21.1 n-succinyl-ala-ala-pro-phe-4-nitroanilide bos taurus 13.5 9.4 13 PMID:19224136 -3.4.21.1 n-succinyl-ala-ala-pro-phe-4-nitroanilide musca domestica 3.8 3.8 1 PMID:22808532 -3.4.21.1 n-succinyl-ala-ala-pro-phe-7-amido-4-methylcoumarin musca domestica 42.0 42.0 1 PMID:22808532 -3.4.21.1 n-succinyl-ala-ala-pro-phe-p-nitroanilide bos taurus 110.0 93.5 2 PMID:11342033 -3.4.21.1 n-succinyl-ala-ala-pro-phe-p-nitroanilide struthio camelus 10.58 10.58 1 PMID:18598777 -3.4.21.1 n-succinyl-ala-phe-ala bos taurus 1.2 1.05 2 PMID:12705836 -3.4.21.1 n-succinyl-ala-phe-p-nitroanilide bos taurus 0.65 0.65 1 PMID:12705836 -3.4.21.1 n-succinyl-l-ala-ala-phe-p-nitroanilide bos taurus 39.0 39.0 1 * -3.4.21.1 n-succinyl-l-ala-ala-pro-p-nitroanilide sardinops sagax 18.6 18.6 1 * -3.4.21.1 n-succinyl-l-ala-ala-pro-phe-p-nitroanilide bos taurus 7.8 7.8 1 * -3.4.21.1 n-succinyl-l-alanyl-l-alanyl-l-prolyl-l-phenylalanine p-nitroanilide homo sapiens 34.6 30.35 2 PMID:35934298 -3.4.21.1 n-succinyl-l-phe-p-nitroanilide bos taurus 0.014 0.014 1 * -3.4.21.1 n-succinyl-l-phenylalanine-4-nitroanilide bos taurus 1.177 0.48 9 PMID:24703063 -3.4.21.1 n-succinyl-leu-leu-val-tyr-7-amido-4-methylcoumarin musca domestica 23.9 23.9 1 PMID:22808532 -3.4.21.1 nalpha-benzyloxycarbonyl-l-ala p-nitrophenyl ester bos taurus 6.43 0.3 3 PMID:7046788 -3.4.21.1 nalpha-benzyloxycarbonyl-l-lys p-nitrophenyl ester bos taurus 0.6 0.6 1 PMID:7046788 -3.4.21.1 nalpha-benzyloxycarbonyl-l-tyr p-nitrophenyl ester bos taurus 85.0 85.0 1 PMID:7046788 -3.4.21.1 nalpha-tosyl-l-tyr benzyl ester bos taurus 21.4 21.4 1 PMID:7046788 -3.4.21.1 p-nitrophenyl acetate bos taurus 0.028 0.0225 2 PMID:14641111 -3.4.21.1 suc-ala-ala-pro-phe-4-nitroanilide pterygoplichthys disjunctivus 19.24 19.24 1 PMID:22752357 -3.4.21.1 succinyl-ala-ala-pro-phe-7-amido-4-methylcoumarin rattus norvegicus 98.3 98.3 1 PMID:11733020 -3.4.21.1 succinyl-ala-ala-pro-phe-p-nitroanilide sardinops caeruleus 18.6 11.700000000000001 2 * -3.4.21.1 succinyl-ala-ala-pro-tyr-7-amido-4-methylcoumarin rattus norvegicus 105.0 105.0 1 PMID:11733020 -3.4.21.1 succinyl-l-ala-ala-pro-l-phe-4-nitroanilide panulirus interruptus 1.07 1.07 1 PMID:25877639 -3.4.21.1 succinyl-l-ala-ala-pro-l-phenylalanine-p-nitroanilide bos taurus 1.9 1.9 1 * -3.4.21.1 succinyl-l-ala-l-ala-l-pro-l-leu-4-nitroanilide sepia officinalis 3.6 3.6 1 * -3.4.21.1 succinyl-l-ala-l-ala-l-pro-l-phe-4-nitroanilide penaeus californiensis 21.5 21.5 1 PMID:25466006 -3.4.21.1 succinyl-l-ala-l-ala-l-pro-l-phe-4-nitroanilide sepia officinalis 18.0 18.0 1 * -3.4.21.1 succinyl-leu-leu-val-tyr-7-amido-4-methylcoumarin bos taurus 0.9 0.9 1 * -3.4.21.1 succinyl-leu-leu-val-tyr-7-amido-4-methylcoumarin carassius auratus 3.4 3.05 2 * -3.4.21.10 aminobenzoyl-ser-lys-gly-arg-ser-leu-ile-gly-lys(dinitrophenyl)-asp sus scrofa 320.0 320.0 1 PMID:11078894 -3.4.21.10 methyl n2-[(4-methylphenyl)sulfonyl]-l-argininate ovis aries 49.0 49.0 1 PMID:1191254 -3.4.21.10 nalpha-benzoyl-l-arg ethyl ester ovis aries 162.0 162.0 1 PMID:1191254 -3.4.21.100 7-amido-4-methylcoumaryl-lys-pro-pro-leu-glu-tyr-arg-leu-gly-lys(onp)-gly pseudomonas sp. 101 73.0 73.0 1 PMID:35862020 -3.4.21.100 lys-pro-ala-asp-phe-4-nitrophenylalanine-arg-leu pseudomonas sp. 6.8 6.8 1 PMID:1562589 -3.4.21.100 lys-pro-ala-glu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 57.6 31.8 2 PMID:9880800 -3.4.21.100 lys-pro-ala-leu-phe-nph-arg-leu pseudomonas sp. 101 51.4 51.4 1 PMID:35862020 -3.4.21.100 lys-pro-ala-leu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 59.3 33.15 2 PMID:10488127 -3.4.21.100 lys-pro-ala-lys-phe-4-nitrophenylalanine-arg-leu pseudomonas sp. 14.7 14.7 1 PMID:1562589 -3.4.21.100 lys-pro-arg-glu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 53.1 53.1 1 PMID:9880800 -3.4.21.100 lys-pro-asn-gln-phe-4-nitrophenylalanine-arg-leu pseudomonas sp. 5.5 5.5 1 PMID:1562589 -3.4.21.100 lys-pro-asn-glu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 47.1 47.1 1 PMID:9880800 -3.4.21.100 lys-pro-asp-glu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 9.68 5.89 2 PMID:9880800 -3.4.21.100 lys-pro-gln-glu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 24.5 24.5 1 PMID:9880800 -3.4.21.100 lys-pro-glu-glu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 3.82 3.4749999999999996 2 PMID:9880800 -3.4.21.100 lys-pro-ile-ala-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 27.7 27.7 1 PMID:9880800 -3.4.21.100 lys-pro-ile-arg-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 12.5 12.5 1 PMID:9880800 -3.4.21.100 lys-pro-ile-asn-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 8.79 5.38 2 PMID:9880800 -3.4.21.100 lys-pro-ile-asp-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 20.9 20.9 1 PMID:9880800 -3.4.21.100 lys-pro-ile-gln-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 10.4 10.4 1 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-(4-nitro)phe-arg-leu pseudomonas sp. 6.9 6.9 1 PMID:1562589 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-ala-leu pseudomonas sp. 19.0 19.0 1 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-ala pseudomonas sp. 15.5 15.5 1 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-arg pseudomonas sp. 3.64 3.385 2 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-asp pseudomonas sp. 40.7 40.7 1 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-ile pseudomonas sp. 10.9 10.9 1 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 32.4 18.05 2 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-phe pseudomonas sp. 10.7 10.7 1 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-ser pseudomonas sp. 44.4 44.4 1 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-tyr pseudomonas sp. 9.87 5.984999999999999 2 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-val pseudomonas sp. 11.6 11.6 1 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-asn-leu pseudomonas sp. 12.9 6.7 2 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-asp-leu pseudomonas sp. 33.0 33.0 1 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-glu-leu pseudomonas sp. 33.3 16.6585 2 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-ile-leu pseudomonas sp. 5.24 4.27 2 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-leu-leu pseudomonas sp. 8.38 4.445 2 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-lys-leu pseudomonas sp. 54.1 27.37 2 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-ser-leu pseudomonas sp. 11.8 11.8 1 PMID:9880800 -3.4.21.100 lys-pro-ile-glu-phe-p-nitrophenylalanine-val-leu pseudomonas sp. 5.38 4.34 2 PMID:9880800 -3.4.21.100 lys-pro-ile-his-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 6.0 4.465 2 PMID:9880800 -3.4.21.100 lys-pro-ile-ile-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 18.3 18.3 1 PMID:9880800 -3.4.21.100 lys-pro-ile-leu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 27.2 27.2 1 PMID:9880800 -3.4.21.100 lys-pro-ile-lys-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 9.75 9.75 1 PMID:9880800 -3.4.21.100 lys-pro-ile-nle-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 14.8 7.675000000000001 2 PMID:9880800 -3.4.21.100 lys-pro-ile-pro-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 29.3 29.3 1 PMID:9880800 -3.4.21.100 lys-pro-ile-ser-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 14.8 7.675000000000001 2 PMID:9880800 -3.4.21.100 lys-pro-ile-thr-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 22.9 22.9 1 PMID:9880800 -3.4.21.100 lys-pro-ile-val-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 15.7 15.7 1 PMID:9880800 -3.4.21.100 lys-pro-leu-glu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 3.1 3.1 1 PMID:9880800 -3.4.21.100 lys-pro-lys-glu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 56.3 28.9 2 PMID:9880800 -3.4.21.100 lys-pro-ser-glu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 20.4 20.4 1 PMID:9880800 -3.4.21.100 lys-pro-thr-glu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 7.92 4.215 2 PMID:9880800 -3.4.21.100 lys-pro-val-glu-phe-p-nitrophenylalanine-arg-leu pseudomonas sp. 14.8 7.675000000000001 2 PMID:9880800 -3.4.21.100 lys-pro-val-ser-tyr-4-nitrophenylalanine-arg-leu pseudomonas sp. 0.0867 0.0867 1 PMID:1562589 -3.4.21.100 mca-lys-pro-pro-leu-glu-tyr-arg-leu-gly-lys(dnp)-gly pseudomonas sp. 73.0 73.0 1 PMID:14733955 -3.4.21.100 phe-pro-ala-p-nitroanilide aspergillus fumigatus 35.0 35.0 1 PMID:16517617 -3.4.21.101 1-(4-methoxyphenyl)-2-methyl-3-nitro-1-h-indol-6-ol xanthomonas sp. 52.2 52.2 1 * -3.4.21.101 lys-pro-ala-asp-phe-(4-nitro)phe-arg-leu pseudomonas sp. 20.4 20.4 1 PMID:7929375 -3.4.21.101 lys-pro-ala-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 79.4 39.815000000000005 2 PMID:9880800 -3.4.21.101 lys-pro-ala-lys-phe-(4-nitro)phe-arg-leu pseudomonas sp. 19.2 19.2 1 PMID:7929375 -3.4.21.101 lys-pro-arg-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 105.0 105.0 1 PMID:9880800 -3.4.21.101 lys-pro-asn-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 38.3 38.3 1 PMID:9880800 -3.4.21.101 lys-pro-asp-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 18.1 18.1 1 PMID:9880800 -3.4.21.101 lys-pro-gln-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 73.9 38.050000000000004 2 PMID:9880800 -3.4.21.101 lys-pro-glu-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 62.4 48.2 2 PMID:9880800 -3.4.21.101 lys-pro-ile-ala-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 60.5 60.5 1 PMID:9880800 -3.4.21.101 lys-pro-ile-arg-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 43.3 43.3 1 PMID:9880800 -3.4.21.101 lys-pro-ile-asn-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 35.7 18.25 2 PMID:9880800 -3.4.21.101 lys-pro-ile-asp-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 18.6 18.6 1 PMID:9880800 -3.4.21.101 lys-pro-ile-gln-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 48.8 48.8 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-ala-leu xanthomonas sp. 1.4 1.4 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-ala xanthomonas sp. 24.7 24.7 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-arg xanthomonas sp. 15.5 15.5 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-asp xanthomonas sp. 101.0 101.0 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-ile xanthomonas sp. 27.3 27.3 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 102.0 102.0 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-phe xanthomonas sp. 26.7 26.7 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-ser xanthomonas sp. 71.3 36.449999999999996 2 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-tyr xanthomonas sp. 27.6 27.6 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-arg-val xanthomonas sp. 30.9 30.9 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-asn-leu xanthomonas sp. 32.7 32.7 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-asp-leu xanthomonas sp. 87.9 68.95 2 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-glu-leu xanthomonas sp. 189.0 189.0 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-ile-leu xanthomonas sp. 16.1 16.1 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-leu-leu xanthomonas sp. 31.0 31.0 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-lys-leu xanthomonas sp. 43.7 43.7 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-ser-leu xanthomonas sp. 40.4 40.4 1 PMID:9880800 -3.4.21.101 lys-pro-ile-glu-phe-p-nitrophenylalanine-val-leu xanthomonas sp. 8.57 5.2700000000000005 2 PMID:9880800 -3.4.21.101 lys-pro-ile-his-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 23.1 20.0 2 PMID:9880800 -3.4.21.101 lys-pro-ile-ile-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 19.4 10.25 2 PMID:9880800 -3.4.21.101 lys-pro-ile-leu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 16.8 16.8 1 PMID:9880800 -3.4.21.101 lys-pro-ile-lys-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 16.6 8.785 2 PMID:9880800 -3.4.21.101 lys-pro-ile-nle-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 39.8 39.8 1 PMID:9880800 -3.4.21.101 lys-pro-ile-pro-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 57.9 31.95 2 PMID:9880800 -3.4.21.101 lys-pro-ile-ser-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 56.8 56.8 1 PMID:9880800 -3.4.21.101 lys-pro-ile-thr-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 30.5 30.5 1 PMID:9880800 -3.4.21.101 lys-pro-ile-val-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 26.9 21.4 2 PMID:9880800 -3.4.21.101 lys-pro-leu-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 15.3 15.3 1 PMID:9880800 -3.4.21.101 lys-pro-lys-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 96.4 96.4 1 PMID:9880800 -3.4.21.101 lys-pro-phe-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 57.3 29.95 2 PMID:9880800 -3.4.21.101 lys-pro-ser-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 36.7 20.05 2 PMID:9880800 -3.4.21.101 lys-pro-thr-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 37.0 37.0 1 PMID:9880800 -3.4.21.101 lys-pro-tyr-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 8.45 8.45 1 PMID:9880800 -3.4.21.101 lys-pro-val-glu-phe-p-nitrophenylalanine-arg-leu xanthomonas sp. 28.1 28.1 1 PMID:9880800 -3.4.21.102 ac-waraaaraaarbaab escherichia coli 3.7 3.7 1 PMID:8520476 -3.4.21.102 arc repressor escherichia coli 0.19 0.19 1 PMID:8520476 -3.4.21.104 abz-glqralei-lys(dnp)-nh2 homo sapiens 1.27 1.27 1 PMID:22071314 -3.4.21.104 abz-slgrkiqi-lys(dnp)-nh2 homo sapiens 1.92 1.92 1 PMID:22071314 -3.4.21.104 c1-inhibitor p4-p1 fragment homo sapiens 0.25 0.25 1 PMID:17709141 -3.4.21.104 c1-inhibitor p4-p4' fragment homo sapiens 35.32 17.81 2 PMID:17709141 -3.4.21.104 complement component c2 homo sapiens 5.6 5.1 5 PMID:11527969;PMID:12538697;PMID:16227207 -3.4.21.104 complement component c2 p4-p1 fragment homo sapiens 31.86 17.78 2 PMID:17709141 -3.4.21.104 complement component c2 p4-p4' fragment homo sapiens 99.58 99.58 1 PMID:17709141 -3.4.21.104 complement component c4 homo sapiens 3.2 2.05 6 PMID:11527969;PMID:12538697;PMID:16040602;PMID:16227207 -3.4.21.104 complement component c4 p4-p1 fragment homo sapiens 4.54 4.54 1 PMID:17709141 -3.4.21.104 complement component c4 p4-p4' fragment homo sapiens 9.35 5.66 2 PMID:17709141 -3.4.21.104 n-acetylglycine-l-lysine methyl ester homo sapiens 133.0 133.0 1 PMID:11527969 -3.4.21.104 n-carboxybenzoylglycine-l-arginine thiobenzyl ester homo sapiens 12.7 12.7 1 PMID:11527969 -3.4.21.104 nalpha-benzoyl-l-arginine ethyl ester homo sapiens 2.4 2.4 1 PMID:11527969 -3.4.21.104 p-tosyl-l-arginine methyl ester homo sapiens 7.1 7.1 1 PMID:11527969 -3.4.21.105 bodipy fl casein escherichia coli 0.007 0.00605 2 PMID:23353827 -3.4.21.105 cypet-tata-ypet providencia stuartii 0.0028 0.0028 1 PMID:25009246 -3.4.21.105 fl-casein escherichia coli 0.062 0.062 1 PMID:25009246 -3.4.21.105 fl-casein haemophilus influenzae 0.063 0.063 1 PMID:25009246 -3.4.21.105 fl-casein providencia stuartii 0.06 0.06 1 PMID:25009246 -3.4.21.105 tata escherichia coli 0.0017 0.0017 1 PMID:25009246 -3.4.21.105 tata haemophilus influenzae 0.07 0.07 1 PMID:25009246 -3.4.21.105 tata providencia stuartii 0.018 0.018 1 PMID:25009246 -3.4.21.106 abz-kqsrkfvpy(3-no2) homo sapiens 12.0 12.0 1 PMID:19302215 -3.4.21.106 abz-raarvvggy(3-no2) homo sapiens 0.5 0.5 1 PMID:19302215 -3.4.21.106 abz-rkrrgsrgy(3-no2) homo sapiens 66.0 66.0 1 PMID:19302215 -3.4.21.106 abz-rlarvvggy(3-no2) homo sapiens 0.6 0.6 1 PMID:19302215 -3.4.21.106 abz-rqaravggy(3-no2) homo sapiens 0.5 0.5 1 PMID:19302215 -3.4.21.106 abz-rqarvvggy(3-no2) homo sapiens 1.4 1.4 1 PMID:19302215 -3.4.21.106 abz-rqaryvggy(3-no2) homo sapiens 0.5 0.5 1 PMID:19302215 -3.4.21.106 abz-rqlrvvggy(3-no2) homo sapiens 1.5 1.5 1 PMID:19302215 -3.4.21.106 abz-rqrraleky(3-no2) homo sapiens 39.0 39.0 1 PMID:19302215 -3.4.21.106 abz-rqrrvvggy(3-no2) homo sapiens 1.4 1.4 1 PMID:19302215 -3.4.21.106 abz-rqyrvvggy(3-no2) homo sapiens 1.1 1.1 1 PMID:19302215 -3.4.21.106 abz-rrarvvggy(3-no2) homo sapiens 0.5 0.5 1 PMID:19302215 -3.4.21.106 abz-skgrsligy(3-no2) homo sapiens 15.0 15.0 1 PMID:19302215 -3.4.21.106 abz-sklrvvggy(3-no2) homo sapiens 16.0 16.0 1 PMID:19302215 -3.4.21.106 pro-urokinase-type plasminogen activator homo sapiens 0.00145 0.00145 1 PMID:16908524 -3.4.21.107 beta-casein homo sapiens 0.00056 0.00056 1 PMID:31280864 -3.4.21.107 l-ala(mca)irrvsysf-anb-nh2 homo sapiens 0.000109 0.000109 1 PMID:31470122 -3.4.21.108 (7-methoxycoumarin-4-yl)airrvsysf-(5-amino-2-nitro)benzamide homo sapiens 0.05 0.05 1 PMID:22851136 -3.4.21.108 2-aminobenzoic acid-ile-met-thr-abu-tyr-met-his-tyr(3-no2)-nh2 homo sapiens 0.22 0.22 1 PMID:25640585 -3.4.21.108 2-aminobenzoic acid-ile-met-thr-abu-tyr-met-phe-tyr(3-no2)-nh2 homo sapiens 0.33 0.33 1 PMID:25640585 -3.4.21.108 2-aminobenzoic acid-ile-met-thr-abu-tyr-met-trp-tyr(3-no2)-nh2 homo sapiens 0.17 0.17 1 PMID:25640585 -3.4.21.108 2-aminobenzoic acid-ile-met-thr-ser-tyr-met-phe-tyr(3-no2)-nh2 homo sapiens 0.01 0.01 1 PMID:25640585 -3.4.21.108 2-aminobenzoic acid-ile-met-val-abu-tyr-met-phe-tyr(3-no2)-nh2 homo sapiens 0.13 0.13 1 PMID:25640585 -3.4.21.108 2-aminobenzoic acid-ile-met-val-ser-tyr-met-phe-tyr(3-no2)-nh2 homo sapiens 0.08 0.08 1 PMID:25640585 -3.4.21.108 ala(7-methoxycoumarin-4-acetic acid)-irrvsysf-(5-amido-2-nitrobenzamide) homo sapiens 0.03 0.029 3 PMID:26110759 -3.4.21.108 beta-casein homo sapiens 0.0204 0.003 3 PMID:23457469;PMID:35074587 -3.4.21.108 spmfkgv-para-nitroaniline bacteria 0.56 0.56 1 PMID:18175296 -3.4.21.109 abz-ile-arg-ala-arg-ser-ala-ala-tyr(3-no2)-nh2 homo sapiens 2.24 2.24 1 PMID:24161741 -3.4.21.109 abz-ile-arg-ala-arg-ser-ala-gly-tyr(3-no2)-nh2 homo sapiens 3.79 3.79 1 PMID:24161741 -3.4.21.109 abz-ile-arg-ala-arg-ser-ala-ser-tyr(3-no2)-nh2 homo sapiens 2.66 2.66 1 PMID:24161741 -3.4.21.109 alphaebeta7 integrin homo sapiens 45.0 26.1 2 PMID:19302215 -3.4.21.109 filaggrin homo sapiens 32.0 19.4 2 PMID:19302215 -3.4.21.109 ile-pro-arg-p-nitroanilide homo sapiens 390000.0 390000.0 1 PMID:30409910 -3.4.21.109 matriptase homo sapiens 1.5 1.25 2 PMID:19302215 -3.4.21.109 methylsulfonyl-d-cyclohexyltyrosyl-glycyl-arginine-p-nitroanilide rattus norvegicus 59.0 59.0 2 * -3.4.21.109 methylsulfonyl-d-cyclohexyltyrosylglycyl-arginine-p-nitroanilide rattus norvegicus 103.0 75.0 4 PMID:19800422 -3.4.21.109 pro-urokinase plasminogen activator homo sapiens 0.89 0.89 1 PMID:17475279 -3.4.21.109 protease-activated receptor-2 homo sapiens 61.0 31.6 2 PMID:19302215 -3.4.21.109 raarvvgg homo sapiens 0.3 0.3 1 PMID:19302215 -3.4.21.109 rlarvvgg homo sapiens 0.3 0.3 1 PMID:19302215 -3.4.21.109 rqaravgg homo sapiens 5.5 2.9 2 PMID:19302215 -3.4.21.109 rqarqvgg homo sapiens 0.8 0.8 1 PMID:19302215 -3.4.21.109 rqarvvgg homo sapiens 1.5 1.25 2 PMID:19302215 -3.4.21.109 rqaryvgg homo sapiens 2.0 2.0 1 PMID:19302215 -3.4.21.109 rqlrvvgg homo sapiens 0.5 0.5 1 PMID:19302215 -3.4.21.109 rqrrvvgg homo sapiens 26.0 26.0 1 PMID:19302215 -3.4.21.109 rqyrvvgg homo sapiens 0.7 0.7 1 PMID:19302215 -3.4.21.109 rrarvvgg homo sapiens 0.9 0.6 2 PMID:19302215 -3.4.21.109 ryarvvgg homo sapiens 0.6 0.6 1 PMID:19302215 -3.4.21.109 single-chain urokinase-type plasminogen activator rattus norvegicus 0.71 0.6399999999999999 2 PMID:19202271 -3.4.21.109 t-butyloxycarbonyl-l-gln-l-ala-l-arg-4-methyl-coumaryl-7-amide rattus norvegicus 13.7 13.399999999999999 2 PMID:19202271 -3.4.21.109 trask homo sapiens 46.0 26.6 2 PMID:19302215 -3.4.21.110 c75-bodipy-labeled recombinant human c5a peptide streptococcus pyogenes 1.006 1.006 1 PMID:36147677 -3.4.21.110 sqlranishkdmqlgr streptococcus pyogenes 1.1 1.1 1 PMID:12354115 -3.4.21.110 vvasqlranish streptococcus pyogenes 0.2 0.2 1 PMID:12354115 -3.4.21.111 n-succinyl-ala-ala-ala-4-nitroanilide thermus aquaticus 2.6 1.3 5 PMID:10348901;PMID:3162211 -3.4.21.111 n-succinyl-ala-ala-phe-4-nitroanilide thermus aquaticus 2.5 2.5 2 PMID:9860855 -3.4.21.111 n-succinyl-ala-ala-pro-phe-4-nitroanilide thermus aquaticus 98.1 80.4 9 PMID:10348901;PMID:17169970;PMID:18216068;PMID:25136511;PMID:9145532;PMID:9882104 -3.4.21.111 n-succinyl-ala-ala-val-4-nitroanilide thermus aquaticus 0.047 0.047 1 * -3.4.21.111 n-succinyl-ala-ala-val-ala-4-nitroanilide thermus aquaticus 18.0 18.0 1 PMID:9145532 -3.4.21.111 n-succinyl-ala-pro-ala-4-nitroanilide thermus aquaticus 0.48 0.48 1 * -3.4.21.111 n-succinyl-gly-gly-phe-4-nitroanilide thermus aquaticus 0.15 0.15 2 PMID:9860855 -3.4.21.111 n-succinyl-ile-val-ala-4-nitroanilide thermus aquaticus 8.1 6.55 2 * -3.4.21.111 n-succinyl-phe-ala-ala-4-nitroanilide thermus aquaticus 11.0 0.14 4 PMID:10348901;PMID:9860855 -3.4.21.111 n-succinyl-phe-leu-ala-4-nitroanilide thermus aquaticus 3.6 3.45 2 PMID:9860855 -3.4.21.111 n-succinyl-phe-nle-ala-4-nitroanilide thermus aquaticus 47400.0 8.8 5 PMID:8733236;PMID:9860855;PMID:9882104 -3.4.21.111 n-succinyl-phe-val-ala-4-nitroanilide thermus aquaticus 4.7 4.7 1 PMID:9860855 -3.4.21.111 n-succinyl-phe-val-leu-4-nitroanilide thermus aquaticus 0.069 0.069 1 * -3.4.21.111 n-succinyl-phe-val-phe-4-nitroanilide thermus aquaticus 5.0 5.0 1 * -3.4.21.111 n-tert-butyloxycarbonyl-val-leu-gly-arg-4-nitroanilide thermus aquaticus 26.0 26.0 1 PMID:9145532 -3.4.21.112 abz-diyisrrllgtfty(no2)a homo sapiens 0.046 0.046 1 PMID:16973377 -3.4.21.112 ac-arg-arg-leu-leu-p-nitroanilide homo sapiens 0.03 0.03 1 PMID:16973377 -3.4.21.112 ac-arg-ser-leu-lys-p-nitroanilide homo sapiens 0.005 0.005 1 PMID:16973377 -3.4.21.114 dabsyl-lys-thr-ala-tyr-phe-gln-leu-glu-gly-arg-his-phe-glu-edans porcine reproductive and respiratory syndrome virus 0.0073 0.0073 1 PMID:19646449 -3.4.21.117 abz-aikffsa-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.03 0.03 1 PMID:25448018 -3.4.21.117 abz-alfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.1 0.1 1 PMID:25448018 -3.4.21.117 abz-flfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.09 0.09 1 PMID:25448018 -3.4.21.117 abz-gfspfrssri-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.03 0.03 1 PMID:25448018 -3.4.21.117 abz-gfspfrssrigeikeett-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 1.0 1.0 1 PMID:25448018 -3.4.21.117 abz-glfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.03 0.03 1 PMID:25448018 -3.4.21.117 abz-hlfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.1 0.1 1 PMID:25448018 -3.4.21.117 abz-ilfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.06 0.06 1 PMID:25448018 -3.4.21.117 abz-kafssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.02 0.02 1 PMID:25448018 -3.4.21.117 abz-kffssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.02 0.02 1 PMID:25448018 -3.4.21.117 abz-klfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.1 0.1 1 PMID:25448018 -3.4.21.117 abz-klyssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.85 0.85 1 PMID:25448018 -3.4.21.117 abz-kpfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.02 0.02 1 PMID:25448018 -3.4.21.117 abz-kvfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.04 0.04 1 PMID:25448018 -3.4.21.117 abz-kyfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.02 0.02 1 PMID:25448018 -3.4.21.117 abz-llfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.07 0.07 1 PMID:25448018 -3.4.21.117 abz-mislmkrp-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.01 0.01 1 PMID:25448018 -3.4.21.117 abz-nlfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.28 0.28 1 PMID:25448018 -3.4.21.117 abz-qlfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.15 0.15 1 PMID:25448018 -3.4.21.117 abz-rlfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.13 0.13 1 PMID:25448018 -3.4.21.117 abz-vlfssk-q-n-[2,4-dinitrophenyl]-ethylenediamine homo sapiens 0.13 0.13 1 PMID:25448018 -3.4.21.117 ac-efkpilwrlgc-(6-(9-oxo-9h-acridin-10-yl)-hexanoate)e-nh2 homo sapiens 0.48 0.48 1 PMID:19171917 -3.4.21.117 acetyl-phe-val-arg-4-nitroanilide homo sapiens 0.04 0.04 1 PMID:8702990 -3.4.21.117 khlf-4-nitroanilide homo sapiens 7.4 7.4 1 PMID:27697464 -3.4.21.117 khly-4-nitroanilide homo sapiens 12.0 12.0 1 PMID:27697464 -3.4.21.117 l-phe-7-amido-4-methylcoumarin homo sapiens 1.6e-05 1.6e-05 1 PMID:17909180 -3.4.21.117 l-tyr-7-amido-4-methylcoumarin homo sapiens 3.3e-05 3.3e-05 1 PMID:17909180 -3.4.21.117 methoxy-succinyl-arg-pro-tyr-4-nitroanilide homo sapiens 1.2 1.2 2 PMID:27697464;PMID:8702990 -3.4.21.117 methoxy-succinyl-arg-pro-tyr-7-amido-4-methylcoumarin homo sapiens 24.5 24.5 1 PMID:28754951 -3.4.21.117 phe-7-amido-4-methylcoumarin homo sapiens 3.3e-05 2.45e-05 2 PMID:17909180 -3.4.21.117 qhly-4-nitroanilide homo sapiens 7.7 7.7 1 PMID:27697464 -3.4.21.117 succinyl-phe-leu-phe-4-nitroanilide homo sapiens 0.05 0.05 1 PMID:8702990 -3.4.21.118 benzyloxycarbonyl-gly-gly-arg-7-amido-4-methylcoumarin homo sapiens 1.49 1.49 1 PMID:20940292 -3.4.21.118 benzyloxycarbonyl-l-val-l-val-l-arg-7-amido-4-methylcoumarin homo sapiens 140.0 140.0 1 PMID:16337200 -3.4.21.118 l-pro-l-phe-l-arg-7-amido-4-methylcoumarin homo sapiens 180.0 180.0 1 PMID:16337200 -3.4.21.118 pro-phe-arg-4-methylcoumaryl-7-amide mus musculus 193.0 193.0 1 PMID:11854276 -3.4.21.118 pro-phe-arg-7-amido-4-methylcoumarin homo sapiens 4.45 4.45 1 PMID:20940292 -3.4.21.118 t-butyloxycarbonyl-l-leu-l-lys-l-arg-7-amido-4-methylcoumarin homo sapiens 65.0 65.0 1 PMID:16337200 -3.4.21.118 t-butyloxycarbonyl-l-phe-l-ser-l-arg-7-amido-4-methylcoumarin homo sapiens 40.0 40.0 1 PMID:16337200 -3.4.21.118 t-butyloxycarbonyl-l-val-l-leu-l-lys-7-amido-4-methylcoumarin homo sapiens 48.0 48.0 1 PMID:16337200 -3.4.21.118 t-butyloxycarbonyl-l-val-l-pro-l-arg-7-amido-4-methylcoumarin homo sapiens 98.0 98.0 1 PMID:16337200 -3.4.21.118 tert-butyloxycarbonyl-asp(benzyloxy)-pro-arg-4-methylcoumaryl-7-amide mus musculus 31.3 31.3 1 PMID:11854276 -3.4.21.118 tert-butyloxycarbonyl-gln-ala-arg-7-amido-4-methylcoumarin homo sapiens 5.75 5.75 1 PMID:20940292 -3.4.21.118 tert-butyloxycarbonyl-gln-arg-arg-7-amido-4-methylcoumarin homo sapiens 3.39 3.39 1 PMID:20940292 -3.4.21.118 tert-butyloxycarbonyl-gln-gly-arg-7-amido-4-methylcoumarin homo sapiens 1.43 1.43 1 PMID:20940292 -3.4.21.118 tert-butyloxycarbonyl-leu-arg-arg-7-amido-4-methylcoumarin homo sapiens 1.62 1.62 1 PMID:20940292 -3.4.21.118 tert-butyloxycarbonyl-leu-lys-arg-7-amido-4-methylcoumarin homo sapiens 1.56 1.56 1 PMID:20940292 -3.4.21.118 tert-butyloxycarbonyl-phe-ser-arg-4-methylcoumaryl-7-amide mus musculus 34.8 34.8 1 PMID:11854276 -3.4.21.118 tert-butyloxycarbonyl-phe-ser-arg-7-amido-4-methylcoumarin homo sapiens 3.57 3.57 1 PMID:20940292 -3.4.21.118 tert-butyloxycarbonyl-val-leu-lys-7-amido-4-methylcoumarin homo sapiens 9.64 9.64 1 PMID:20940292 -3.4.21.118 tert-butyloxycarbonyl-val-pro-arg-4-methylcoumaryl-7-amide mus musculus 100.0 100.0 1 PMID:11854276 -3.4.21.118 tert-butyloxycarbonyl-val-pro-arg-7-amido-4-methylcoumarin homo sapiens 6.76 6.76 1 PMID:20940292 -3.4.21.118 tosyl-gly-pro-arg-7-amido-4-methylcoumarin homo sapiens 2.11 2.11 1 PMID:20940292 -3.4.21.119 abz-klksskq-eddnp homo sapiens 0.5 0.3 2 PMID:21689719 -3.4.21.119 abz-klrsskq-eddnp homo sapiens 3.4 3.3 2 PMID:21689719 -3.4.21.119 abz-val-arg-phe-arg-5-amino-2-nitrobenzoic acid homo sapiens 94.36 94.36 1 PMID:30925705 -3.4.21.119 abz-vrfrstg-tyr(3-no2)-nh2 homo sapiens 169.4 169.4 1 PMID:30925705 -3.4.21.119 abz-vrfrstq-tyr(3-no2)-nh2 homo sapiens 96.4 96.4 1 PMID:30925705 -3.4.21.119 abz-vrfrsts-tyr(3-no2)-nh2 homo sapiens 113.1 113.1 1 PMID:30925705 -3.4.21.120 nalpha-tert-butoxycarbonylphenylalanylserylarginyl-7-amido-4-methylcoumarin xenopus laevis 3.8 3.8 1 PMID:1581303 -3.4.21.122 boc-leu-gly-arg-7-amido-4-methylcoumarin homo sapiens 18.0 18.0 1 PMID:35676539 -3.4.21.123 ala-pro-ala-lys-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 6.08 3.31 2 PMID:10965051 -3.4.21.123 iqf peptide alicyclobacillus sendaiensis 395.0 395.0 1 PMID:16704427 -3.4.21.123 leu-pro-ala-lys-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 0.26 0.26 1 PMID:10965051 -3.4.21.123 lys-ala-ala-lys-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 6.5 6.5 1 PMID:10965051 -3.4.21.123 lys-arg-ala-lys-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 6.08 6.08 1 PMID:10965051 -3.4.21.123 lys-asp-ala-lys-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 6.08 3.77 2 PMID:10965051 -3.4.21.123 lys-leu-ala-lys-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 20.3 20.3 1 PMID:10965051 -3.4.21.123 lys-pro-ala-ala-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 98.3 98.3 1 PMID:10965051 -3.4.21.123 lys-pro-ala-arg-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 6.08 3.5300000000000002 2 PMID:10965051 -3.4.21.123 lys-pro-ala-lys-phe-(p-nitrophenylalanine)-arg-ala bacillus novosp. 0.22 0.22 1 PMID:10965051 -3.4.21.123 lys-pro-ala-lys-phe-(p-nitrophenylalanine)-arg-arg bacillus novosp. 6.08 3.56 2 PMID:10965051 -3.4.21.123 lys-pro-ala-lys-phe-(p-nitrophenylalanine)-arg-asp bacillus novosp. 0.19 0.19 1 PMID:10965051 -3.4.21.123 lys-pro-ala-lys-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 0.41 0.41 1 PMID:10965051 -3.4.21.123 lys-pro-ala-lys-phe-(p-nitrophenylalanine)-arg-ser bacillus novosp. 0.45 0.45 1 PMID:10965051 -3.4.21.123 lys-pro-ala-ser-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 19.9 11.7 2 PMID:10965051 -3.4.21.123 lys-pro-arg-glu-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 32.3 32.3 1 PMID:10965051 -3.4.21.123 lys-pro-arg-lys-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 6.08 3.605 2 PMID:10965051 -3.4.21.123 lys-pro-asn-glu-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 4.62 3.96 2 PMID:10965051 -3.4.21.123 lys-pro-asp-glu-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 6.0 4.5600000000000005 2 PMID:10965051 -3.4.21.123 lys-pro-asp-lys-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 6.08 3.36 2 PMID:10965051 -3.4.21.123 lys-pro-gln-glu-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 16.1 16.1 1 PMID:10965051 -3.4.21.123 lys-pro-glu-glu-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 13.1 13.1 1 PMID:10965051 -3.4.21.123 lys-pro-ile-ala-phe-(4-nitro)phe-arg-leu bacillus novosp. 6.02 6.02 1 PMID:15242607 -3.4.21.123 lys-pro-ile-ala-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 48.5 48.5 1 PMID:10965051 -3.4.21.123 lys-pro-ile-asn-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 9.14 5.555000000000001 2 PMID:10965051 -3.4.21.123 lys-pro-ile-asp-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 81.0 54.8 2 PMID:10965051 -3.4.21.123 lys-pro-ile-gln-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 4.79 4.045 2 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-ala-leu bacillus novosp. 7.7 7.7 1 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-arg-asp bacillus novosp. 21.7 21.7 1 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-arg-ile bacillus novosp. 12.5 12.5 1 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 25.4 25.4 1 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-arg-nle bacillus novosp. 34.2 34.2 1 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-arg-phe bacillus novosp. 31.9 17.8 2 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-arg-tyr bacillus novosp. 15.9 15.9 1 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-arg-val bacillus novosp. 13.1 13.1 1 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-asn-leu bacillus novosp. 6.0 4.74 2 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-asp-leu bacillus novosp. 8.78 5.375 2 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-glu-leu bacillus novosp. 22.7 22.7 1 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-ile-leu bacillus novosp. 2.94 2.38 2 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-leu-leu bacillus novosp. 23.9 23.9 1 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-lys-leu bacillus novosp. 10.9 10.9 1 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-ser-leu bacillus novosp. 2.6 2.6 1 PMID:10965051 -3.4.21.123 lys-pro-ile-glu-phe-(p-nitrophenylalanine)-val-leu bacillus novosp. 5.04 4.17 2 PMID:10965051 -3.4.21.123 lys-pro-ile-his-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 3.0 3.0 1 PMID:10965051 -3.4.21.123 lys-pro-ile-ile-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 0.3 0.3 1 PMID:10965051 -3.4.21.123 lys-pro-ile-leu-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 6.08 3.46 2 PMID:10965051 -3.4.21.123 lys-pro-ile-pro-phe-(4-nitrophenyl)-arg-leu heyndrickxia coagulans 176.0 176.0 1 * -3.4.21.123 lys-pro-ile-pro-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 176.0 176.0 1 PMID:10965051 -3.4.21.123 lys-pro-ile-ser-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 52.7 52.7 1 PMID:10965051 -3.4.21.123 lys-pro-ile-thr-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 6.0 4.74 2 PMID:10965051 -3.4.21.123 lys-pro-ile-val-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 6.08 3.4050000000000002 2 PMID:10965051 -3.4.21.123 lys-pro-leu-glu-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 4.44 3.785 2 PMID:10965051 -3.4.21.123 lys-pro-phe-glu-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 3.76 3.445 2 PMID:10965051 -3.4.21.123 lys-pro-ser-glu-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 2.1 2.1 1 PMID:10965051 -3.4.21.123 lys-pro-ser-lys-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 6.08 3.335 2 PMID:10965051 -3.4.21.123 lys-pro-thr-glu-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 16.7 16.7 1 PMID:10965051 -3.4.21.123 lys-pro-val-glu-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 18.6 18.6 1 PMID:10965051 -3.4.21.123 lys-ser-ala-lys-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 2.35 2.35 1 PMID:10965051 -3.4.21.123 oxidized insulin b-chain bacillus novosp. 71.0 71.0 1 PMID:8416942 -3.4.21.123 ser-pro-ala-lys-phe-(p-nitrophenylalanine)-arg-leu bacillus novosp. 0.27 0.27 1 PMID:10965051 -3.4.21.19 benzyloxycarbonyl-ala-ala-glu-4-nitroanilide bacillus licheniformis 40.9 40.9 1 PMID:1429718 -3.4.21.19 benzyloxycarbonyl-ala-ala-glu-4-nitroanilide staphylococcus aureus 20.8 20.8 1 PMID:1429718 -3.4.21.19 benzyloxycarbonyl-ala-glu-p-nitroanilide bacillus licheniformis 5.9 5.9 1 PMID:1429718 -3.4.21.19 benzyloxycarbonyl-ala-glu-p-nitroanilide staphylococcus aureus 5.6 5.6 1 PMID:1429718 -3.4.21.19 benzyloxycarbonyl-ala-leu-glu-p-nitroanilide bacillus licheniformis 131.0 95.95 2 PMID:1429718 -3.4.21.19 benzyloxycarbonyl-glu-4-nitroanilide bacillus intermedius 81.0 81.0 1 PMID:14640964 -3.4.21.19 benzyloxycarbonyl-glu-p-nitroanilide bacillus licheniformis 0.28 0.28 1 PMID:1429718 -3.4.21.19 benzyloxycarbonyl-glu-p-nitroanilide staphylococcus aureus 0.29 0.29 1 PMID:1429718 -3.4.21.19 benzyloxycarbonyl-l-ala-l-ala-l-leu-l-glu-4-nitroanilide bacillus intermedius 16.6 16.6 1 PMID:15187226 -3.4.21.19 benzyloxycarbonyl-leu-glu-p-nitroanilide bacillus licheniformis 22.6 22.6 1 PMID:1429718 -3.4.21.19 benzyloxycarbonyl-leu-glu-p-nitroanilide staphylococcus aureus 31.4 31.4 1 PMID:1429718 -3.4.21.19 benzyloxycarbonyl-leu-leu-glu-p-nitroanilide bacillus licheniformis 50.8 50.8 1 PMID:1429718 -3.4.21.19 benzyloxycarbonyl-leu-leu-glu-p-nitroanilide staphylococcus aureus 30.2 30.2 1 PMID:1429718 -3.4.21.19 benzyloxycarbonyl-phe-leu-glu-p-nitroanilide bacillus licheniformis 40.9 40.9 1 PMID:1429718 -3.4.21.19 benzyloxycarbonyl-phe-leu-glu-p-nitroanilide staphylococcus aureus 33.2 33.2 1 PMID:1429718 -3.4.21.19 l-phe-l-leu-l-glu-4-nitroanilide staphylococcus aureus 44.4 44.4 1 PMID:21347511 -3.4.21.19 leu-leu-glu-4-methylcoumaryl-7-amide staphylococcus epidermidis 9059.0 7695.0 5 PMID:19090719 -3.4.21.19 succinyl-ala-ala-pro-glu-p-nitroanilide streptomyces griseus 38.3 38.3 1 PMID:8931145 -3.4.21.19 t-butyloxycarbonyl-ala-ala-asp-p-nitroanilide bacillus licheniformis 0.16 0.16 1 PMID:1429718 -3.4.21.19 t-butyloxycarbonyl-ala-ala-asp-p-nitroanilide staphylococcus aureus 0.54 0.54 1 PMID:1429718 -3.4.21.19 t-butyloxycarbonyl-ala-ala-glu-p-nitroanilide bacillus licheniformis 11.9 11.9 1 PMID:1429718 -3.4.21.19 t-butyloxycarbonyl-ala-ala-glu-p-nitroanilide staphylococcus aureus 24.0 24.0 1 PMID:1429718 -3.4.21.2 acetyl-l-leu methyl ester sus scrofa 50.0 50.0 1 PMID:4672120 -3.4.21.2 acetyl-l-trp ethyl ester sus scrofa 0.32 0.32 1 PMID:14253410 -3.4.21.2 acetyl-tyr ethyl ester sus scrofa 92.0 92.0 1 PMID:1260039 -3.4.21.2 benzoyl-l-leu ethyl ester sus scrofa 25.4 25.4 1 PMID:14253410 -3.4.21.2 benzoyl-l-leu methyl ester sus scrofa 28.0 28.0 1 PMID:4672120 -3.4.21.2 benzoyl-l-met ethyl ester sus scrofa 1.7 1.7 1 PMID:14253410 -3.4.21.2 benzoyl-l-phe ethyl ester sus scrofa 1.55 1.55 1 PMID:14253410 -3.4.21.2 benzoyl-l-tyr ethyl ester sus scrofa 80.0 63.0 2 PMID:14253410;PMID:4672120 -3.4.21.2 benzyloxycarbonyl-l-leu-gly amide sus scrofa 0.013 0.013 1 PMID:14253410 -3.4.21.2 n-acetyl-tyr ethyl ester sus scrofa 170.0 170.0 1 PMID:4672120 -3.4.21.2 n-succinyl-ala-ala-pro-phe-4-nitroanilide homo sapiens 11.7 11.7 1 PMID:30640231 -3.4.21.2 succinyl-ala-ala-pro-ala 4-nitroanilide homo sapiens 0.3 0.3 1 PMID:23035638 -3.4.21.2 succinyl-ala-ala-pro-asn 4-nitroanilide homo sapiens 3.6 3.6 1 PMID:23035638 -3.4.21.2 succinyl-ala-ala-pro-gln 4-nitroanilide homo sapiens 1.1 1.1 1 PMID:23035638 -3.4.21.2 succinyl-ala-ala-pro-ile 4-nitroanilide homo sapiens 0.03 0.03 1 PMID:23035638 -3.4.21.2 succinyl-ala-ala-pro-leu 4-nitroanilide homo sapiens 9.2 9.2 1 PMID:23035638 -3.4.21.2 succinyl-ala-ala-pro-met 4-nitroanilide homo sapiens 14.9 14.9 1 PMID:23035638 -3.4.21.2 succinyl-ala-ala-pro-phe 4-nitroanilide homo sapiens 15.0 14.1 2 PMID:22942235;PMID:23035638 -3.4.21.2 succinyl-ala-ala-pro-phe-4-nitroanilide homo sapiens 15.4 15.4 1 PMID:26013824 -3.4.21.2 succinyl-ala-ala-pro-trp 4-nitroanilide homo sapiens 0.1 0.1 1 PMID:23035638 -3.4.21.2 succinyl-ala-ala-pro-tyr 4-nitroanilide homo sapiens 16.6 16.6 1 PMID:23035638 -3.4.21.2 succinyl-ala-ala-pro-val 4-nitroanilide homo sapiens 0.05 0.05 1 PMID:23035638 -3.4.21.20 7-methoxycoumarin-4-yl-acetyl-phe-val-thr-(4-guanidine-l-phenylalanyl)-amino benzoyl-nh2 homo sapiens 0.025 0.025 1 PMID:18261971 -3.4.21.20 7-methoxycoumarin-4-yl-acetyl-phe-val-thr-(4-guanidine-l-phenylalanyl)-ser-amino benzoyl-nh2 homo sapiens 0.421 0.421 1 PMID:18261971 -3.4.21.20 7-methoxycoumarin-4-yl-acetyl-phe-val-thr-(4-guanidine-l-phenylalanyl)-ser-asp-amino benzoyl-nh2 homo sapiens 6.08 3.342 2 PMID:18261971 -3.4.21.20 7-methoxycoumarin-4-yl-acetyl-phe-val-thr-(4-guanidine-l-phenylalanyl)-ser-phe-amino benzoyl-nh2 homo sapiens 0.512 0.512 1 PMID:18261971 -3.4.21.20 7-methoxycoumarin-4-yl-acetyl-phe-val-thr-(4-guanidine-l-phenylalanyl)-ser-trp-amino benzoyl-nh2 homo sapiens 6.08 3.302 2 PMID:18261971 -3.4.21.20 acetyl-phe-val-thr-(4-guanidine-l-phenylalanyl)-amino benzoyl-nh2 homo sapiens 19.0 19.0 1 PMID:18261971 -3.4.21.20 methoxysuccinyl-l-alanine-l-alanine-l-proline-l-valine-p-nitroanilide homo sapiens 6.0 6.0 1 PMID:6566611 -3.4.21.20 methoxysuccinyl-l-alanine-l-alanine-l-proline-l-valine-p-nitrophenylanilide rattus norvegicus 16.5 16.5 1 PMID:6566611 -3.4.21.20 n-acetyl-l-phenylalanine-p-nitrophenyl ester homo sapiens 68.3 68.3 1 PMID:6566611 -3.4.21.20 n-acetyl-l-phenylalanine-p-nitrophenyl ester rattus norvegicus 20.2 20.2 1 PMID:6566611 -3.4.21.20 n-benzoyl-l-tyrosine ethyl ester homo sapiens 3.0 3.0 1 PMID:7245 -3.4.21.20 n-succinyl-l-val-l-pro-l-phe-4-nitroanilide homo sapiens 100.0 57.0 2 PMID:20889553 -3.4.21.20 n-succinyl-l-val-l-pro-l-phe-4-nitroanilide mus musculus 41.0 37.0 2 PMID:20889553 -3.4.21.21 benzyloxycarbonyl-arg-p-nitrobenzyl ester bos taurus 1.8 1.8 1 PMID:632264 -3.4.21.21 d-ile-pro-arg-4-nitroanilide homo sapiens 34.6 3.72985 6 PMID:26694616;PMID:34076594 -3.4.21.21 d-ile-pro-arg-p-nitroanilide homo sapiens 44.2 20.185 4 PMID:11278475 -3.4.21.21 factor x homo sapiens 94.0 0.24684999999999999 14 PMID:10052945;PMID:11078728;PMID:11389142;PMID:11560488;PMID:11583150;PMID:11698657;PMID:14686879;PMID:16406236;PMID:19490111;PMID:22275370 -3.4.21.21 methanesulfonyl-d-cyclohexylalanyl-butyl-arginine p-nitroanilide homo sapiens 17.0 17.0 1 PMID:12358603 -3.4.21.21 n-methylsulfonyl-d-phe-gly-arg-p-nitroanilide homo sapiens 396000.0 36000.0 22 PMID:11078728;PMID:11876644;PMID:12135351 -3.4.21.21 s-2288 homo sapiens 13.0 13.0 1 PMID:22275370 -3.4.21.21 spectrozyme fviia homo sapiens 17.0 17.0 1 PMID:11931672 -3.4.21.22 4-methylsulfonyl-d-leu-gly-arg-p-nitroanilide homo sapiens 3.38 1.89 4 PMID:15913649 -3.4.21.22 ch3so2-d-leu-gly-arg-4-nitroanilide homo sapiens 21.9 20.2 7 PMID:16732371;PMID:16829135 -3.4.21.22 ch3so2-d-leu-gly-l-arg-p-nitroanilide homo sapiens 13.2 13.2 1 PMID:12721300 -3.4.21.22 factor x homo sapiens 110.0 1.0 29 PMID:11009614;PMID:11052674;PMID:11278963;PMID:12721300;PMID:15039440;PMID:15328360;PMID:15755260;PMID:17563121;PMID:19656280;PMID:20628058;PMID:2249997;PMID:25795563;PMID:30350119 -3.4.21.22 l-leu-gly-l-arg-4-nitroanilide homo sapiens 21.4 19.45 2 PMID:20628058 -3.4.21.22 methoxycarbonyl-d-nle-gly-arg-p-nitroanilide homo sapiens 2.01 2.01 1 PMID:9256238 -3.4.21.22 methylsulfonyl-d-cyclohexylglycyl-gly-arg-p-nitroanilide homo sapiens 5.67 5.67 1 PMID:9256238 -3.4.21.22 methylsulfonyl-d-hexahydrotyrosyl-gly-arg-p-nitroanilide homo sapiens 6.11 6.11 1 PMID:9256238 -3.4.21.25 ala-ala-pro-ala-p-nitroanilide cucumis melo 2.51 2.51 1 * -3.4.21.25 ala-ala-pro-glu-p-nitroanilide cucumis melo 1.21 1.21 1 * -3.4.21.25 ala-ala-pro-gly-p-nitroanilide cucumis melo 0.043 0.043 1 * -3.4.21.25 ala-ala-pro-l-diaminopropionic acid-p-nitroanilide cucumis melo 0.603 0.603 1 * -3.4.21.25 ala-ala-pro-leu-p-nitroanilide cucumis melo 23.9 23.9 1 * -3.4.21.25 ala-ala-pro-lys-p-nitroanilide cucumis melo 0.295 0.295 1 * -3.4.21.25 ala-ala-pro-phe-p-nitroanilide cucumis melo 5.26 5.26 1 * -3.4.21.25 ala-ala-pro-val-p-nitroanilide cucumis melo 0.022 0.022 1 * -3.4.21.25 benzoyl-tyr-ethyl ester cucumis melo 0.22 0.22 1 PMID:7576259 -3.4.21.25 benzyloxycarbonyl-ala-ala-ala-sch2c6h5 cucumis melo 0.767 0.767 1 * -3.4.21.25 benzyloxycarbonyl-ala-ala-arg-sch2c6h5 cucumis melo 0.0833 0.0833 1 * -3.4.21.25 benzyloxycarbonyl-ala-ala-asp-sch2c6h5 cucumis melo 0.417 0.417 1 * -3.4.21.25 benzyloxycarbonyl-ala-ala-glu-sch2c6h5 cucumis melo 0.0333 0.0333 1 * -3.4.21.25 benzyloxycarbonyl-ala-ala-leu-sch2c6h5 cucumis melo 0.8 0.8 1 * -3.4.21.25 benzyloxycarbonyl-ala-ala-norleucine-sch2c6h5 cucumis melo 0.817 0.817 1 * -3.4.21.25 benzyloxycarbonyl-ala-ala-norvaline-sch2c6h5 cucumis melo 1.13 1.13 1 * -3.4.21.25 benzyloxycarbonyl-ala-ala-phe-sch2c6h5 cucumis melo 0.317 0.317 1 * -3.4.21.25 benzyloxycarbonyl-ala-ala-ser-sch2c6h5 cucumis melo 0.9 0.9 1 * -3.4.21.25 benzyloxycarbonyl-ala-ala-val-sch2c6h5 cucumis melo 0.167 0.167 1 * -3.4.21.25 benzyloxycarbonyl-ala-asn-sch2c6h5 cucumis melo 0.517 0.517 1 * -3.4.21.25 benzyloxycarbonyl-tyr 4-nitrophenyl ester cucumis melo 2.2 2.2 1 PMID:7576259 -3.4.21.25 glutaryl-ala-ala-pro-leu-p-nitroanilide cucumis melo 5.9 5.9 1 PMID:8586630 -3.4.21.25 l-alanyl-4-nitroanilide ficus religiosa 32.13 32.13 1 * -3.4.21.25 l-alanyl-l-alanyl-4-nitroanilide ficus religiosa 25.48 25.48 1 * -3.4.21.25 l-gamma-glutamyl-4-nitroanilide ficus religiosa 207.8 207.8 1 * -3.4.21.25 l-leucyl-4-nitroanilide ficus religiosa 749.7 749.7 1 * -3.4.21.25 leu-leu-pro-ala-ala-leu cucumis melo 14.0 14.0 1 PMID:11129582 -3.4.21.25 leu-leu-pro-asn-ala-leu cucumis melo 98.0 98.0 1 PMID:11129582 -3.4.21.25 leu-leu-pro-gln-ala-leu cucumis melo 162.0 162.0 1 PMID:11129582 -3.4.21.25 leu-leu-pro-glu-ala-leu cucumis melo 5.0 5.0 1 PMID:11129582 -3.4.21.25 leu-leu-pro-glu-lys-leu cucumis melo 4.0 4.0 1 PMID:11129582 -3.4.21.25 leu-leu-pro-glu-ser-leu cucumis melo 7.0 7.0 1 PMID:11129582 -3.4.21.25 leu-leu-pro-his-ala-leu cucumis melo 59.0 59.0 1 PMID:11129582 -3.4.21.25 leu-leu-pro-leu-ala-leu cucumis melo 20.0 20.0 1 PMID:11129582 -3.4.21.25 leu-leu-pro-met-ala-leu cucumis melo 177.0 177.0 1 PMID:11129582 -3.4.21.25 leu-leu-pro-phe-ala-leu cucumis melo 5.0 5.0 1 PMID:11129582 -3.4.21.25 leu-leu-pro-ser-ala-leu cucumis melo 3.0 3.0 1 PMID:11129582 -3.4.21.25 leu-leu-pro-thr-ala-leu cucumis melo 27.0 27.0 1 PMID:11129582 -3.4.21.25 succinyl-ala-ala-ala-p-nitroanilide cucumis melo 0.013 0.013 1 PMID:8586630 -3.4.21.25 succinyl-ala-ala-p-nitroanilide cucumis melo 0.007 0.007 1 PMID:8586630 -3.4.21.25 succinyl-ala-ala-pro-phe-p-nitroanilide cucumis melo 4.17 4.17 1 PMID:8586630 -3.4.21.25 succinyl-ala-p-nitroanilide cucumis melo 0.002 0.002 1 PMID:8586630 -3.4.21.25 succinyl-ala-pro-ala-p-nitroanilide cucumis melo 0.31 0.31 1 PMID:8586630 -3.4.21.26 2-aminobenzoyl-arg-pro-pro-gly-phe-ser-pro-phe-arg-gln-n-(2,4-dinitrophenyl)ethylenediamine sus scrofa 1.1 1.1 1 PMID:17904692 -3.4.21.26 2-aminobenzoyl-arg-pro-pro-gly-phe-ser-pro-phe-arg-ser-ser-arg-gln-n-(2,4-dinitrophenyl)ethylenediamine sus scrofa 0.9 0.9 1 PMID:17904692 -3.4.21.26 2-aminobenzoyl-glu-gly-phe-ser-pro-phe(no2)-arg-ala sus scrofa 7.22 3.885 2 PMID:14514675 -3.4.21.26 2-aminobenzoyl-glu-phe-ser-pro-phe(no2)-arg-ala sus scrofa 1.7 1.7 1 PMID:14514675 -3.4.21.26 2-aminobenzoyl-gly-glu-ser-pro-phe(no2)-arg-ala sus scrofa 2.94 2.38 2 PMID:14514675 -3.4.21.26 2-aminobenzoyl-gly-phe-arg-pro-phe(no2)-arg-ala sus scrofa 3.2 3.2 1 PMID:14514675 -3.4.21.26 2-aminobenzoyl-gly-phe-glu-pro-phe(no2)-arg-ala sus scrofa 2.4 2.4 1 PMID:14514675 -3.4.21.26 2-aminobenzoyl-gly-phe-gly-pro-phe-gly-phe(no2)-ala-nh2 sus scrofa 5.38 4.34 2 PMID:12228249 -3.4.21.26 2-aminobenzoyl-gly-phe-ser-pro-phe-arg-gln-n-(2,4-dinitrophenyl)ethylenediamine sus scrofa 1.4 1.4 1 PMID:17904692 -3.4.21.26 2-aminobenzoyl-gly-phe-ser-pro-phe-arg-ser-ser-arg-gln-n-(2,4-dinitrophenyl)ethylenediamine sus scrofa 1.5 1.5 1 PMID:17904692 -3.4.21.26 2-aminobenzoyl-gly-pro-gln-n-(2,4-dinitrophenyl)ethylenediamine sus scrofa 7.9 4.65 2 PMID:17904692 -3.4.21.26 2-aminobenzoyl-gly-pro-phe-arg-gln-n-(2,4-dinitrophenyl)ethylenediamine sus scrofa 4.0 4.0 1 PMID:17904692 -3.4.21.26 2-aminobenzoyl-gly-pro-phe-gln-n-(2,4-dinitrophenyl)ethylenediamine sus scrofa 6.0 6.0 1 PMID:17904692 -3.4.21.26 2-aminobenzoyl-gly-ser-pro-phe-arg-gln-n-(2,4-dinitrophenyl)ethylenediamine sus scrofa 3.5 3.5 1 PMID:17904692 -3.4.21.26 abz-gly-l-phe-l-arg-l-pro-l-phe(no2)-l-arg-l-ala homo sapiens 0.97 0.97 1 PMID:22940581 -3.4.21.26 ala-gly-pro-beta-naphthylamide lyophyllum cinerascens 15.9 15.9 1 * -3.4.21.26 ala-pro-4-nitroanilide pyrococcus furiosus 0.079 0.079 1 PMID:11278687 -3.4.21.26 ala-pro-p-nitroanilide pyrococcus furiosus 0.079 0.079 1 PMID:14521416 -3.4.21.26 angiotensin i bos taurus 0.85 0.85 1 PMID:3071531 -3.4.21.26 arg-pro-4-nitroanilide pyrococcus furiosus 16.9 8.465 2 PMID:11278687 -3.4.21.26 arg-pro-p-nitroanilide pyrococcus furiosus 0.03 0.03 1 PMID:14521416 -3.4.21.26 asp-pro-4-nitroanilide pyrococcus furiosus 0.073 0.073 1 PMID:11278687 -3.4.21.26 asp-pro-p-nitroanilide pyrococcus furiosus 0.073 0.073 1 PMID:14521416 -3.4.21.26 benzyloxycarbonyl-ala-ala-4-nitroanilide pyrococcus furiosus 2.5 2.5 1 PMID:11278687 -3.4.21.26 benzyloxycarbonyl-ala-ala-beta-naphthylamide elizabethkingia meningoseptica 5.9 5.9 1 * -3.4.21.26 benzyloxycarbonyl-ala-ala-p-nitroanilide pyrococcus furiosus 2.5 2.5 1 PMID:14521416 -3.4.21.26 benzyloxycarbonyl-ala-ala-p-nitrophenol elizabethkingia meningoseptica 2.7 2.7 1 * -3.4.21.26 benzyloxycarbonyl-ala-gly-pro-beta-naphthylamide elizabethkingia meningoseptica 192.0 192.0 1 * -3.4.21.26 benzyloxycarbonyl-ala-gly-pro-beta-naphthylamide lyophyllum cinerascens 0.82 0.82 1 * -3.4.21.26 benzyloxycarbonyl-ala-gly-pro-p-nitrophenol ovis aries 38.2 38.2 1 * -3.4.21.26 benzyloxycarbonyl-ala-pro-4-nitroanilide pyrococcus furiosus 17.9 17.9 1 PMID:11278687 -3.4.21.26 benzyloxycarbonyl-ala-pro-beta-naphthylamide elizabethkingia meningoseptica 4.2 4.2 1 * -3.4.21.26 benzyloxycarbonyl-ala-pro-p-nitroanilide lyophyllum cinerascens 126.0 126.0 1 * -3.4.21.26 benzyloxycarbonyl-ala-pro-p-nitroanilide pyrococcus furiosus 17.9 17.9 1 PMID:14521416 -3.4.21.26 benzyloxycarbonyl-ala-pro-p-nitrophenol ovis aries 61.0 61.0 1 * -3.4.21.26 benzyloxycarbonyl-d-ala-gly-pro-beta-naphthylamide elizabethkingia meningoseptica 38.0 38.0 1 * -3.4.21.26 benzyloxycarbonyl-d-ala-gly-pro-beta-naphthylamide lyophyllum cinerascens 2.0 2.0 1 * -3.4.21.26 benzyloxycarbonyl-d-ala-gly-pro-p-nitrophenol ovis aries 30.0 30.0 1 * -3.4.21.26 benzyloxycarbonyl-d-ala-pro-beta-naphthylamide elizabethkingia meningoseptica 0.147 0.147 1 * -3.4.21.26 benzyloxycarbonyl-gly-gly-pro-p-nitrophenol elizabethkingia meningoseptica 85.8 43.925 2 * -3.4.21.26 benzyloxycarbonyl-gly-gly-pro-p-nitrophenol ovis aries 27.0 27.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-l-pro-4-nitroanilide coprinopsis clastophylla 162.0 162.0 1 PMID:22923115 -3.4.21.26 benzyloxycarbonyl-gly-l-pro-4-nitroanilide sphaerobacter thermophilus 60.0 60.0 1 PMID:28899487 -3.4.21.26 benzyloxycarbonyl-gly-l-pro-7-amido-4-methylcoumarin coprinopsis clastophylla 26.6 26.6 1 PMID:22923115 -3.4.21.26 benzyloxycarbonyl-gly-l-pro-beta-naphthylamide mus musculus 4.7 4.7 1 PMID:15857608 -3.4.21.26 benzyloxycarbonyl-gly-pro-4-methylcoumaryl-7-amide elizabethkingia meningoseptica 115.0 115.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-4-methylcoumaryl-7-amide lyophyllum cinerascens 0.95 0.95 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-ala elizabethkingia meningoseptica 240.0 240.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-ala lyophyllum cinerascens 6.08 3.67 2 * -3.4.21.26 benzyloxycarbonyl-gly-pro-ala ovis aries 15.6 15.6 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-beta-naphthylamide elizabethkingia meningoseptica 169.0 169.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-beta-naphthylamide lyophyllum cinerascens 153.0 153.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-beta-naphthylamide sus scrofa 32.5 32.5 1 PMID:12228249 -3.4.21.26 benzyloxycarbonyl-gly-pro-d-ala ovis aries 2.94 2.23 2 * -3.4.21.26 benzyloxycarbonyl-gly-pro-d-leu ovis aries 6.08 3.375 2 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu elizabethkingia meningoseptica 23.0 23.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu lyophyllum cinerascens 1.05 1.05 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu ovis aries 26.0 26.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-ala elizabethkingia meningoseptica 520.0 520.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-ala lyophyllum cinerascens 13.2 13.2 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-ala ovis aries 38.4 38.4 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-d-ala elizabethkingia meningoseptica 1600.0 1600.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-d-ala lyophyllum cinerascens 5.67 5.67 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-d-ala ovis aries 46.0 46.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-gly elizabethkingia meningoseptica 520.0 520.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-gly lyophyllum cinerascens 7.98 4.245 2 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-gly ovis aries 52.0 52.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-gly-ala elizabethkingia meningoseptica 1000.0 1000.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-gly-ala ovis aries 34.0 34.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-gly-d-ala ovis aries 25.0 25.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-gly-gly elizabethkingia meningoseptica 700.0 700.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-gly-gly ovis aries 8.0 8.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-gly-pro lyophyllum cinerascens 12.4 12.4 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-leu-gly-pro ovis aries 53.3 26.849999999999998 2 * -3.4.21.26 benzyloxycarbonyl-gly-pro-p-nitroanilide lyophyllum cinerascens 3.8 3.8 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-p-nitroanilide pyrococcus furiosus 16.9 16.9 1 PMID:14521416 -3.4.21.26 benzyloxycarbonyl-gly-pro-p-nitrophenol elizabethkingia meningoseptica 102.0 102.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-p-nitrophenol ovis aries 32.7 32.7 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-p-nitrophenol sus scrofa 6.0 6.0 1 PMID:12228249 -3.4.21.26 benzyloxycarbonyl-gly-pro-phe elizabethkingia meningoseptica 180.0 180.0 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-phe lyophyllum cinerascens 3.95 3.95 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-phe ovis aries 3.2 3.2 1 * -3.4.21.26 benzyloxycarbonyl-gly-pro-sbzl sus scrofa 108.0 108.0 1 PMID:12228249 -3.4.21.26 benzyloxycarbonyl-pro-p-nitrophenol ovis aries 8.9 8.9 1 * -3.4.21.26 calcitonin gene-related peptide mus musculus 0.072 0.0366 2 PMID:19911840 -3.4.21.26 gly-pro-4-nitroanilide pyrococcus furiosus 0.06 0.06 1 PMID:11278687 -3.4.21.26 gly-pro-p-nitroanilide pyrococcus furiosus 0.06 0.06 1 PMID:14521416 -3.4.21.26 iwgigcnpwtaehvdqtlasgndic galerina marginata 0.58 0.40499999999999997 2 PMID:28332820 -3.4.21.26 l-ala-l-ala-l-pro-4-nitroanilide aspergillus oryzae 139.4 123.4 2 PMID:24241934;PMID:25547787 -3.4.21.26 l-leu-4-nitroanilide pleurotus eryngii 570.0 288.2 2 PMID:29623768 -3.4.21.26 l-phe-4-nitroanilide pleurotus eryngii 4300.0 3100.0 2 PMID:29623768 -3.4.21.26 n-benzyloxycarbonyl-gly-pro-ala ovis aries 6.1 6.1 1 PMID:7028730 -3.4.21.26 n-benzyloxycarbonyl-gly-pro-leu-gly ovis aries 32.3 32.3 1 PMID:7028730 -3.4.21.26 n-succinyl-ala-pro-4-nitroanilide thermococcus onnurineus 22.2 22.2 1 PMID:17434424 -3.4.21.26 n-succinyl-gly-l-pro-l-leu-gly-l-pro-4-methylcoumarin-7-amide leishmania infantum 3101.0 1668.8 2 PMID:32547514 -3.4.21.26 n-succinyl-gly-l-pro-l-leu-gly-l-pro-7-amido-4-methylcoumarin trypanosoma cruzi 48.7 38.400000000000006 2 PMID:15581422 -3.4.21.26 nalpha-benzyl-gly-pro-leu-gly elizabethkingia meningoseptica 29.2 29.2 1 PMID:3539636 -3.4.21.26 nalpha-benzyloxycarbonyl-gly-pro-leu-gly elizabethkingia meningoseptica 17.6 17.6 1 PMID:3539636 -3.4.21.26 thyrotropin-releasing hormone bos taurus 14.4 14.4 1 PMID:3071531 -3.4.21.26 z-gly-l-pro-4-nitroanilide aspergillus oryzae 240.0 172.85 2 PMID:24241934;PMID:25547787 -3.4.21.26 z-gly-pro-4-nitroanilide aeromonas caviae 505.0 505.0 1 PMID:20444688 -3.4.21.26 z-l-ala-l-ala-l-ala-l-pro-4-nitroanilide aspergillus oryzae 93.0 84.0 2 PMID:24241934;PMID:25547787 -3.4.21.27 d-ile-pro-arg-4-nitroanilide homo sapiens 110.2 110.2 1 PMID:18186617 -3.4.21.27 factor fix homo sapiens 0.49 0.49 1 PMID:15829482 -3.4.21.27 factor ix homo sapiens 5.8 0.605 10 PMID:11342438;PMID:15362874;PMID:17676929;PMID:18192270;PMID:21778227 -3.4.21.27 factor ix 10-mer homo sapiens 0.083 0.083 1 PMID:29158361 -3.4.21.27 factor xi homo sapiens 8.0 8.0 1 PMID:10781579 -3.4.21.27 l-pyroglu-l-pro-l-arg-4-nitroanilide homo sapiens 201.0 201.0 1 PMID:21778227 -3.4.21.27 l-pyroglutamyl-l-pro-l-arg-4-nitroanilide homo sapiens 430.0 310.0 3 PMID:11342438 -3.4.21.27 l-pyroglutamyl-l-prolyl-l-argininyl-p-nitroanilide homo sapiens 148.0 133.5 2 PMID:19178150 -3.4.21.27 l-pyroglutamyl-l-prolyl-l-arginyl-p-nitroanilide homo sapiens 117.0 92.0 2 PMID:15829482 -3.4.21.27 prochemerin chem163s homo sapiens 0.91 0.91 1 PMID:29158361 -3.4.21.27 pyroglu-pro-arg-4-nitroanilide homo sapiens 145.0 72.634 2 PMID:18186617;PMID:18192270 -3.4.21.27 pyroglu-pro-arg-p-nitroanilide homo sapiens 350.0 350.0 1 PMID:6604052 -3.4.21.27 s-2366 homo sapiens 121.0 117.0 2 PMID:17676929 -3.4.21.34 2-aminobenzoic acid-gly-phe-ser-pro-phe-arg-ser-ser-arg-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.1 0.1 1 PMID:16895484 -3.4.21.34 acetyl-phe-arg-4-nitroanilide homo sapiens 37.7 37.7 1 PMID:16895484 -3.4.21.34 apelin-17 homo sapiens 13.7 13.7 1 PMID:30690406 -3.4.21.34 factor xii homo sapiens 0.001 0.001 1 PMID:16895484 -3.4.21.34 h-d-pro-phe-arg-4-nitroanilide homo sapiens 37.7 37.7 1 PMID:16895484 -3.4.21.34 high-molecular-weight kininogen homo sapiens 0.0306 0.0306 1 PMID:16895484 -3.4.21.34 kininogen homo sapiens 2.94 2.4 2 PMID:12489800 -3.4.21.34 o-aminobenzoyl-fsapmkrltlgnttq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 46.2 46.2 1 PMID:11004531 -3.4.21.34 o-aminobenzoyl-fsqamkrltlgnttq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 192.0 192.0 1 PMID:11004531 -3.4.21.34 o-aminobenzoyl-fsqfmkrltlgnttq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 90.0 90.0 1 PMID:11004531 -3.4.21.34 o-aminobenzoyl-fsqgmkrltlgnttq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 480.0 480.0 1 PMID:11004531 -3.4.21.34 o-aminobenzoyl-fsqpakrltlgnttq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 18.0 18.0 1 PMID:11004531 -3.4.21.34 o-aminobenzoyl-fsqpmarltlgnttq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 48.0 48.0 1 PMID:11004531 -3.4.21.34 o-aminobenzoyl-fsqpmkratlgnttq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 72.0 72.0 1 PMID:11004531 -3.4.21.34 o-aminobenzoyl-fsqpmkrlalgnttq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 42.0 42.0 1 PMID:11004531 -3.4.21.34 o-aminobenzoyl-fsqpmkrltagnttq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 18.0 18.0 1 PMID:11004531 -3.4.21.34 o-aminobenzoyl-fsqpmkrltlanttq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 6.0 6.0 1 PMID:11004531 -3.4.21.34 o-aminobenzoyl-fsqpmkrltlgattq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 60.0 60.0 1 PMID:11004531 -3.4.21.34 o-aminobenzoyl-fsqpmkrltlgnttq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 60.0 60.0 1 PMID:11004531 -3.4.21.34 o-aminobenzoyl-vmiaalprtmfiq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 0.01 0.01 1 PMID:11258660 -3.4.21.34 o-aminobenzoyl-vvisalprtmfiq-n-(2,4-dinitrophenyl)-ethylene diamine homo sapiens 3.66 3.395 2 PMID:11258660 -3.4.21.34 plasminogen homo sapiens 0.00034 0.00034 1 PMID:16895484 -3.4.21.35 abz-alfsskq-eddnp homo sapiens 0.1 0.1 1 PMID:25448018 -3.4.21.35 abz-flfsskq-eddnp homo sapiens 0.09 0.09 1 PMID:25448018 -3.4.21.35 abz-frssr-q-eddnp homo sapiens 1.6 1.6 1 PMID:23494059 -3.4.21.35 abz-gfspfrslri-q-eddnp homo sapiens 4.6 4.6 1 PMID:23494059 -3.4.21.35 abz-gfspfrssri-q-eddnp homo sapiens 17.7 17.7 1 PMID:23494059 -3.4.21.35 abz-glfsskq-eddnp homo sapiens 0.03 0.03 1 PMID:25448018 -3.4.21.35 abz-hlfsskq-eddnp homo sapiens 0.1 0.1 1 PMID:25448018 -3.4.21.35 abz-ilfsskq-eddnp homo sapiens 0.06 0.06 1 PMID:25448018 -3.4.21.35 abz-kafsskq-eddnp homo sapiens 0.02 0.02 1 PMID:25448018 -3.4.21.35 abz-kffsskq-eddnp homo sapiens 0.02 0.02 1 PMID:25448018 -3.4.21.35 abz-klffsk-eddnp homo sapiens 0.04 0.04 1 PMID:25448018 -3.4.21.35 abz-klfrsk-eddnp homo sapiens 0.04 0.04 1 PMID:25448018 -3.4.21.35 abz-klfsakq-eddnp homo sapiens 0.43 0.43 1 PMID:25448018 -3.4.21.35 abz-klfsgkq-eddnp homo sapiens 0.04 0.04 1 PMID:25448018 -3.4.21.35 abz-klfsikq-eddnp homo sapiens 0.09 0.09 1 PMID:25448018 -3.4.21.35 abz-klfslkq-eddnp homo sapiens 0.15 0.15 1 PMID:25448018 -3.4.21.35 abz-klfsnkq-eddnp homo sapiens 0.04 0.04 1 PMID:25448018 -3.4.21.35 abz-klfsrkq-eddnp homo sapiens 0.15 0.15 1 PMID:25448018 -3.4.21.35 abz-klfssdq-eddnp homo sapiens 0.05 0.05 1 PMID:25448018 -3.4.21.35 abz-klfsseq-eddnp homo sapiens 0.5 0.5 1 PMID:25448018 -3.4.21.35 abz-klfssgq-eddnp homo sapiens 0.09 0.09 1 PMID:25448018 -3.4.21.35 abz-klfssiq-eddnp homo sapiens 0.02 0.02 1 PMID:25448018 -3.4.21.35 abz-klfssk-eddnp homo sapiens 0.1 0.1 1 PMID:25448018 -3.4.21.35 abz-klfsskq-eddnp homo sapiens 0.1 0.1 1 PMID:25448018 -3.4.21.35 abz-klfsslq-eddnp homo sapiens 0.08 0.08 1 PMID:25448018 -3.4.21.35 abz-klfssnq-eddnp homo sapiens 0.07 0.07 1 PMID:25448018 -3.4.21.35 abz-klfssqq-eddnp homo sapiens 0.14 0.14 1 PMID:25448018 -3.4.21.35 abz-klfssrq-eddnp homo sapiens 0.17 0.17 1 PMID:25448018 -3.4.21.35 abz-klfsssq-eddnp homo sapiens 0.43 0.43 1 PMID:25448018 -3.4.21.35 abz-klfssvq-eddnp homo sapiens 0.06 0.06 1 PMID:25448018 -3.4.21.35 abz-klfsvkq-eddnp homo sapiens 0.35 0.35 1 PMID:25448018 -3.4.21.35 abz-klftsk-eddnp homo sapiens 0.04 0.04 1 PMID:25448018 -3.4.21.35 abz-klfwsk-eddnp homo sapiens 0.04 0.04 1 PMID:25448018 -3.4.21.35 abz-klyssk-eddnp homo sapiens 0.85 0.85 1 PMID:25448018 -3.4.21.35 abz-kpfsskq-eddnp homo sapiens 0.02 0.02 1 PMID:25448018 -3.4.21.35 abz-kvfsskq-eddnp homo sapiens 0.04 0.04 1 PMID:25448018 -3.4.21.35 abz-kyfsskq-eddnp homo sapiens 0.02 0.02 1 PMID:25448018 -3.4.21.35 abz-llfsskq-eddnp homo sapiens 0.07 0.07 1 PMID:25448018 -3.4.21.35 abz-mislmklp-q-eddnp homo sapiens 0.02 0.02 1 PMID:23494059 -3.4.21.35 abz-mislmkrp-q-eddnp homo sapiens 0.33 0.33 1 PMID:23494059 -3.4.21.35 abz-nlfsskq-eddnp homo sapiens 0.28 0.28 1 PMID:25448018 -3.4.21.35 abz-qlfsskq-eddnp homo sapiens 0.15 0.15 1 PMID:25448018 -3.4.21.35 abz-rlfsskq-eddnp homo sapiens 0.13 0.13 1 PMID:25448018 -3.4.21.35 abz-vlfsskq-eddnp homo sapiens 0.13 0.13 1 PMID:25448018 -3.4.21.35 acetyl-2-aminohexanoic acid-arg methyl ester sus scrofa 1180.0 1180.0 1 PMID:3643848 -3.4.21.35 acetyl-ala-arg methyl ester sus scrofa 682.0 682.0 1 PMID:3643848 -3.4.21.35 acetyl-ala-arg-ala sus scrofa 0.0542 0.0542 1 PMID:3650053 -3.4.21.35 acetyl-ala-leu-arg-p-nitroanilide sus scrofa 6.74 6.74 1 PMID:2611215 -3.4.21.35 acetyl-ala-phe-arg-ala sus scrofa 0.87 0.87 1 PMID:3650053 -3.4.21.35 acetyl-ala-phe-arg-p-nitroanilide sus scrofa 1.71 1.71 1 PMID:3650053 -3.4.21.35 acetyl-ala-thr-arg-p-nitroanilide sus scrofa 0.72 0.72 1 PMID:2611215 -3.4.21.35 acetyl-arg-ala-nh2 sus scrofa 0.02 0.02 1 PMID:3650053 -3.4.21.35 acetyl-arg-p-nitroanilide sus scrofa 0.05 0.05 1 PMID:3650053 -3.4.21.35 acetyl-d-ala-arg methyl ester sus scrofa 4.6 4.6 1 PMID:3643848 -3.4.21.35 acetyl-d-phe-arg methyl ester sus scrofa 49.0 49.0 1 PMID:3643848 -3.4.21.35 acetyl-glu-leu-arg-p-nitroanilide sus scrofa 9.2 9.2 1 PMID:2611215 -3.4.21.35 acetyl-glu-lys-arg-p-nitroanilide sus scrofa 0.029 0.029 1 PMID:2611215 -3.4.21.35 acetyl-glu-phe-arg-p-nitroanilide sus scrofa 6.62 6.62 1 PMID:2611215 -3.4.21.35 acetyl-glu-thr-arg-p-nitroanilide sus scrofa 0.38 0.38 1 PMID:2611215 -3.4.21.35 acetyl-gly-arg methyl ester sus scrofa 385.0 385.0 1 PMID:3643848 -3.4.21.35 acetyl-gly-arg-ser-val-gln sus scrofa 0.77 0.77 1 PMID:3643848 -3.4.21.35 acetyl-ile-arg methyl ester sus scrofa 727.0 727.0 1 PMID:3643848 -3.4.21.35 acetyl-leu-arg methyl ester sus scrofa 634.0 634.0 1 PMID:3643848 -3.4.21.35 acetyl-met-arg methyl ester sus scrofa 1380.0 1380.0 1 PMID:3643848 -3.4.21.35 acetyl-phe-arg methyl ester sus scrofa 915.0 915.0 1 PMID:3643848 -3.4.21.35 acetyl-phe-arg-ala sus scrofa 0.81 0.81 1 PMID:3650053 -3.4.21.35 acetyl-phe-arg-p-nitroanilide sus scrofa 1.69 1.69 1 PMID:3650053 -3.4.21.35 acetyl-phe-arg-ser-nh2 sus scrofa 2.1 2.1 1 PMID:3643848 -3.4.21.35 acetyl-phe-arg-ser-val-gln sus scrofa 6.8 6.8 1 PMID:3643848 -3.4.21.35 acetyl-phe-arg-ser-val-nh2 sus scrofa 11.6 11.6 1 PMID:3643848 -3.4.21.35 acetyl-pro-arg methyl ester sus scrofa 806.0 806.0 1 PMID:3643848 -3.4.21.35 acetyl-pro-phe-arg-ala sus scrofa 0.24 0.24 1 PMID:3650053 -3.4.21.35 acetyl-pro-phe-arg-p-nitroanilide sus scrofa 0.78 0.78 1 PMID:3650053 -3.4.21.35 acetyl-trp-arg methyl ester sus scrofa 438.0 438.0 1 PMID:3643848 -3.4.21.35 acetyl-tyr-arg methyl ester sus scrofa 680.0 680.0 1 PMID:3643848 -3.4.21.35 acetyl-val-arg methyl ester sus scrofa 964.0 964.0 1 PMID:3643848 -3.4.21.35 ala-arg-arg-7-amido-4-methylcoumarin homo sapiens 0.12 0.12 1 PMID:10411640 -3.4.21.35 benzyloxycarbonyl-arg-ala-nh2 sus scrofa 0.113 0.113 1 PMID:3650053 -3.4.21.35 benzyloxycarbonyl-arg-p-nitroanilide sus scrofa 0.014 0.014 1 PMID:3650053 -3.4.21.35 benzyloxycarbonyl-pro-gly-arg methyl ester sus scrofa 259.0 259.0 1 PMID:3643848 -3.4.21.35 benzyloxycarbonyl-pro-phe-arg methyl ester sus scrofa 537.0 537.0 1 PMID:3643848 -3.4.21.35 d-pro-phe-arg-4-methylcoumarin-7-amide homo sapiens 3.6 3.6 1 PMID:15040788 -3.4.21.35 d-pro-phe-arg-4-methylcoumarin-7-amide mus musculus 3.18 3.18 1 PMID:15040788 -3.4.21.35 d-pro-phe-arg-4-methylcoumarin-7-amide rattus norvegicus 95.3 49.25 2 PMID:15040788 -3.4.21.35 d-pro-phe-phe-4-methylcoumarin-7-amide homo sapiens 12.5 12.5 1 PMID:15040788 -3.4.21.35 d-pro-phe-phe-4-methylcoumarin-7-amide mus musculus 0.085 0.085 1 PMID:15040788 -3.4.21.35 d-pro-phe-phe-4-methylcoumarin-7-amide rattus norvegicus 0.05 0.05 1 PMID:15040788 -3.4.21.35 d-val-leu-arg-p-nitroanilide sus scrofa 6.6 6.6 1 PMID:2611215 -3.4.21.35 d-val-leu-lys-4-nitroanilide sus scrofa 4.1 4.1 1 PMID:2611215 -3.4.21.35 dl-val-leu-arg-p-nitroanilide homo sapiens 1.16 1.07 3 PMID:9535704 -3.4.21.35 fspfrsvq sus scrofa 6.4 6.4 1 PMID:3643848 -3.4.21.35 gln-ala-arg-7-amido-4-methylcoumarin homo sapiens 0.0038 0.0038 1 PMID:16467084 -3.4.21.35 gly-pro-arg-7-amido-4-methylcoumarin homo sapiens 0.0035 0.0035 1 PMID:16467084 -3.4.21.35 leu-leu-arg-7-amido-4-methylcoumarin homo sapiens 0.04 0.04 1 PMID:10411640 -3.4.21.35 n-alpha-acetyl-arg-p-nitroanilide sus scrofa 0.154 0.154 1 PMID:2611215 -3.4.21.35 n-alpha-acetyl-tyr ethyl ester sus scrofa 11.2 11.2 1 PMID:1011997 -3.4.21.35 n-alpha-benzoyl-l-arg ethyl ester sus scrofa 123.0 123.0 1 PMID:1011997 -3.4.21.35 n-alpha-benzoyl-l-arg methyl ester sus scrofa 154.0 154.0 1 PMID:1011997 -3.4.21.35 n-alpha-benzoyl-l-arginine ethyl ester sus scrofa 100.0 72.05 4 PMID:90336040 -3.4.21.35 n-alpha-benzoyl-l-citrulline methyl ester sus scrofa 86.4 86.4 1 PMID:1011997 -3.4.21.35 n-alpha-benzoyl-l-lys methyl ester sus scrofa 15.5 15.5 1 PMID:1011997 -3.4.21.35 n-alpha-benzoyl-l-orn methyl ester sus scrofa 1.8 1.8 1 PMID:1011997 -3.4.21.35 n-alpha-toluenesulfonyl-l-arg methyl ester sus scrofa 2.7 2.7 1 PMID:1011997 -3.4.21.35 n-alpha-tosyl-l-arginine methyl ester sus scrofa 9.38 2.94 4 PMID:90336040 -3.4.21.35 o-aminobenzoyl-aikffire-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 0.05 0.05 1 PMID:12578561 -3.4.21.35 o-aminobenzoyl-aikffqre-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 0.02 0.02 1 PMID:12578561 -3.4.21.35 o-aminobenzoyl-aikffsae-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 0.54 0.54 1 PMID:12578561 -3.4.21.35 o-aminobenzoyl-aikffske-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 0.21 0.21 1 PMID:12578561 -3.4.21.35 o-aminobenzoyl-aikffspe-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 0.05 0.05 1 PMID:12578561 -3.4.21.35 o-aminobenzoyl-aikffsre-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 3.33 3.33 1 PMID:12578561 -3.4.21.35 o-aminobenzoyl-aikffsse-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 0.3 0.3 1 PMID:12578561 -3.4.21.35 o-aminobenzoyl-aikfftre-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 0.04 0.04 1 PMID:12578561 -3.4.21.35 o-aminobenzoyl-frssr-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 1.4 1.4 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-frssr-n-(2,4-dinitrophenyl)ethylene diamine sus scrofa 7.0 7.0 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-frsvq-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 0.9 0.9 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-frsvq-n-(2,4-dinitrophenyl)ethylene diamine sus scrofa 1.6 1.6 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-gfspf-4-(aminocyclohexyl)alanine-ssrpq-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 0.51 0.51 1 PMID:11318645 -3.4.21.35 o-aminobenzoyl-gfspf-4-(aminomethyl)-n-isopropylphenylalanine-ssrpq-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 0.81 0.81 1 PMID:11318645 -3.4.21.35 o-aminobenzoyl-gfspf-4-(aminomethyl)phenylalanine-ssrpq-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 1.8 1.8 1 PMID:11318645 -3.4.21.35 o-aminobenzoyl-gfspf-4-piperidinylalanine-ssrpq-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 0.61 0.61 1 PMID:11318645 -3.4.21.35 o-aminobenzoyl-gfspf-nim-(dimethyl)histidine-ssrpq-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 2.1 2.1 1 PMID:11318645 -3.4.21.35 o-aminobenzoyl-gfspfraprvq-ethylenediamine 2,4-dinitrophenol mus musculus 6.6 6.6 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-gfspfraprvq-ethylenediamine 2,4-dinitrophenol rattus norvegicus 12.0 12.0 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-gfspfrssrigeikeeq-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 3.0 3.0 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-gfspfrssrigeikeeq-n-(2,4-dinitrophenyl)ethylene diamine sus scrofa 3.1 3.1 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-gfspfrssrq-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 7.5 7.5 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-gfspfrssrq-n-(2,4-dinitrophenyl)ethylene diamine sus scrofa 1.0 1.0 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-gfspfrsvq-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 0.94 0.94 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-gfspfrsvq-n-(2,4-dinitrophenyl)ethylene diamine sus scrofa 4.0 4.0 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-gfspfrsvqvmkyegsq-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 1.5 1.5 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-gfspfrsvqvmkyegsq-n-(2,4-dinitrophenyl)ethylene diamine sus scrofa 40.1 40.1 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-gfspfrsvtvq-ethylenediamine 2,4-dinitrophenol homo sapiens 3.1 3.1 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-gfspfrsvtvq-ethylenediamine 2,4-dinitrophenol mus musculus 7.0 7.0 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-gfspfrsvtvq-ethylenediamine 2,4-dinitrophenol rattus norvegicus 14.7 14.7 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-lmkrp-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 0.04 0.04 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-lmkrp-n-(2,4-dinitrophenyl)ethylene diamine sus scrofa 0.076 0.076 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-lprtmfiq-n-(2,4-dinitrophenyl)ethylene diamine sus scrofa 0.032 0.032 1 PMID:10615004 -3.4.21.35 o-aminobenzoyl-lprtmq-n-(2,4-dinitrophenyl)ethylene diamine sus scrofa 0.014 0.014 1 PMID:10615004 -3.4.21.35 o-aminobenzoyl-mtemarrpq-ethylenediamine 2,4-dinitrophenol homo sapiens 0.73 0.73 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-mtemarrpq-ethylenediamine 2,4-dinitrophenol mus musculus 1.49 1.49 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-mtemarrpq-ethylenediamine 2,4-dinitrophenol rattus norvegicus 0.8 0.8 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-mtsvirrpq-ethylenediamine 2,4-dinitrophenol mus musculus 3.27 3.27 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-mtsvirrpq-ethylenediamine 2,4-dinitrophenol rattus norvegicus 5.86 5.86 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-phe-4-(aminomethyl)phenylalanine-ser-arg-gln-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 1.0 1.0 1 PMID:11318645 -3.4.21.35 o-aminobenzoyl-phe-arg-arg-ethylenediamine 2,4-dinitrophenol mus musculus 12.7 12.7 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-phe-arg-arg-ethylenediamine 2,4-dinitrophenol rattus norvegicus 18.7 18.7 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-phe-arg-lys-gfspfrsvtvq-ethylenediamine 2,4-dinitrophenol mus musculus 18.4 18.4 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-phe-arg-lys-gfspfrsvtvq-ethylenediamine 2,4-dinitrophenol rattus norvegicus 21.8 21.8 1 PMID:15040788 -3.4.21.35 o-aminobenzoyl-phe-nim-(dimethyl)histidine-ser-arg-gln-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 1.2 1.2 1 PMID:11318645 -3.4.21.35 o-aminobenzoyl-qplgmislmkrp-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 7.1 7.1 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-qplgmislmkrp-n-(2,4-dinitrophenyl)ethylene diamine sus scrofa 0.4 0.4 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-qplgqtslmkrp-n-(2,4-dinitrophenyl)ethylene diamine homo sapiens 1.1 1.1 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-qplgqtslmkrp-n-(2,4-dinitrophenyl)ethylene diamine sus scrofa 0.6 0.6 1 PMID:10615005 -3.4.21.35 o-aminobenzoyl-vmiaalprtmfiq-n-(2,4-dinitrophenyl)ethylene diamine sus scrofa 0.0005 0.0005 1 PMID:10615004 -3.4.21.35 o-aminobenzoyl-vmiaalprtmq-n-(2,4-dinitrophenyl)ethylene diamine sus scrofa 0.004 0.004 1 PMID:10615004 -3.4.21.35 pfrsvq sus scrofa 5.7 5.7 1 PMID:3643848 -3.4.21.35 phe-arg-ser-val-gln sus scrofa 2.8 2.8 1 PMID:3643848 -3.4.21.35 phe-ser-arg-7-amido-4-methylcoumarin homo sapiens 0.0065 0.0065 1 PMID:16467084 -3.4.21.35 pro-phe-arg-4-methylcoumarin 7-amide homo sapiens 12.5 7.3 5 PMID:12578561;PMID:9535704 -3.4.21.35 pro-phe-arg-7-amido-4-methylcoumarin homo sapiens 0.031 0.031 1 PMID:16467084 -3.4.21.35 pro-phe-arg-arg-7-amido-4-methylcoumarin homo sapiens 0.917 0.917 1 PMID:10411640 -3.4.21.35 rppgfspfrsvq sus scrofa 5.7 5.7 1 PMID:3643848 -3.4.21.35 succinyl-val-pro-phe-thiobenzyl ester homo sapiens 29.0 27.0 3 PMID:9535704 -3.4.21.35 val-pro-arg-7-amido-4-methylcoumarin homo sapiens 0.0075 0.0075 1 PMID:16467084 -3.4.21.35 val-pro-arg-arg-7-amido-4-methylcoumarin homo sapiens 0.0267 0.0267 1 PMID:10411640 -3.4.21.36 4-nitrophenyl acetate sus scrofa 0.0125 0.0081 4 PMID:30880056 -3.4.21.36 succinyl-ala-ala-ala-p-nitroanilide rattus norvegicus 1.59 1.59 1 PMID:6555050 -3.4.21.36 succinyl-ala-ala-pro-ala-p-nitroanilide rattus norvegicus 4.88 4.88 1 PMID:6555050 -3.4.21.36 succinyl-ala-ala-pro-met-p-nitroanilide rattus norvegicus 0.12 0.12 1 PMID:6555050 -3.4.21.36 succinyl-l-ala-l-ala-l-ala-4-nitroanilide sus scrofa 1.039 1.039 1 PMID:27488271 -3.4.21.36 succinyl-l-ala-l-ala-l-pro-gly-4-nitroanilide sus scrofa 1.86 1.86 1 PMID:28062577 -3.4.21.36 succinyl-l-ala-l-ala-l-pro-l-ala-4-nitroanilide homo sapiens 24.8 23.85 2 PMID:28062577 -3.4.21.36 succinyl-l-ala-l-ala-l-pro-l-ala-4-nitroanilide sus scrofa 115.0 115.0 1 PMID:28062577 -3.4.21.36 succinyl-l-ala-l-ala-l-pro-l-ile-4-nitroanilide homo sapiens 1.25 1.12 2 PMID:28062577 -3.4.21.36 succinyl-l-ala-l-ala-l-pro-l-ile-4-nitroanilide sus scrofa 2.87 2.87 1 PMID:28062577 -3.4.21.36 succinyl-l-ala-l-ala-l-pro-l-leu-4-nitroanilide homo sapiens 1.16 1.085 2 PMID:28062577 -3.4.21.36 succinyl-l-ala-l-ala-l-pro-l-leu-4-nitroanilide sus scrofa 57.8 57.8 1 PMID:28062577 -3.4.21.36 succinyl-l-ala-l-ala-l-pro-l-met-4-nitroanilide homo sapiens 0.24 0.24 2 PMID:28062577 -3.4.21.36 succinyl-l-ala-l-ala-l-pro-l-met-4-nitroanilide sus scrofa 0.7 0.7 1 PMID:28062577 -3.4.21.36 succinyl-l-ala-l-ala-l-pro-l-ser-4-nitroanilide homo sapiens 0.26 0.2 2 PMID:28062577 -3.4.21.36 succinyl-l-ala-l-ala-l-pro-l-ser-4-nitroanilide sus scrofa 5.62 5.62 1 PMID:28062577 -3.4.21.36 succinyl-l-ala-l-ala-l-pro-l-val-4-nitroanilide homo sapiens 3.66 3.05 2 PMID:28062577 -3.4.21.36 succinyl-l-ala-l-ala-l-pro-l-val-4-nitroanilide sus scrofa 16.9 16.9 1 PMID:28062577 -3.4.21.37 acetyl-ala-ala-pro-val-4-nitroanilide homo sapiens 8.1 8.1 1 PMID:312290 -3.4.21.37 benzyloxycarbonyl-ala-3-hydroxy-5-phenylpyrrole homo sapiens 20.0 18.0 3 PMID:7487054 -3.4.21.37 benzyloxycarbonyl-ala-4-nitrophenol homo sapiens 46.0 36.0 3 PMID:7487054 -3.4.21.37 heparin-antithrombin complex homo sapiens 3.33 3.33 1 PMID:2732232 -3.4.21.37 methoxysuccinyl-ala-ala-pro-ala-4-nitroanilide homo sapiens 22.0 22.0 1 PMID:3646070 -3.4.21.37 methoxysuccinyl-ala-ala-pro-ala-thiobenzyl ester homo sapiens 52.0 52.0 1 PMID:3646070 -3.4.21.37 methoxysuccinyl-ala-ala-pro-alpha-aminobutyryl-4-nitroanilide homo sapiens 21.0 21.0 1 PMID:3646070 -3.4.21.37 methoxysuccinyl-ala-ala-pro-met-4-nitroanilide homo sapiens 0.72 0.72 2 PMID:312290;PMID:7516152 -3.4.21.37 methoxysuccinyl-ala-ala-pro-val-4-nitroanilide equus caballus 17.9 13.7 2 PMID:7516152 -3.4.21.37 methoxysuccinyl-ala-ala-pro-val-4-nitroanilide homo sapiens 23.0 13.9 4 PMID:1418684;PMID:312290;PMID:3646070;PMID:7516152 -3.4.21.37 methoxysuccinyl-ala-ala-pro-val-4-nitroanilide ovis aries 16.0 16.0 1 PMID:1418684 -3.4.21.37 methoxysuccinyl-ala-ala-pro-val-thiobenzyl ester homo sapiens 13.0 13.0 1 PMID:3646070 -3.4.21.37 methoxysuccinyl-ala-ile-pro-met-4-nitroanilide homo sapiens 6.8 6.8 1 PMID:312290 -3.4.21.37 methoxysuccinyl-ala-pro-ala-4-nitroanilide homo sapiens 7.0 7.0 1 PMID:3646070 -3.4.21.37 methoxysuccinyl-ala-pro-ala-thiobenzyl ester homo sapiens 46.0 46.0 1 PMID:3646070 -3.4.21.37 methoxysuccinyl-ala-pro-val-4-nitroanilide homo sapiens 10.0 10.0 1 PMID:3646070 -3.4.21.37 methoxysuccinyl-ala-pro-val-thiobenzyl ester homo sapiens 13.0 13.0 1 PMID:3646070 -3.4.21.37 methoxysuccinyl-pro-val-4-nitroanilide homo sapiens 0.04 0.04 1 PMID:3646070 -3.4.21.37 methoxysuccinyl-pro-val-thiobenzyl ester homo sapiens 10.0 10.0 1 PMID:3646070 -3.4.21.37 methoxysuccinyl-val-4-nitroanilide homo sapiens 0.06 0.06 1 PMID:3646070 -3.4.21.37 methoxysuccinyl-val-thiobenzyl ester homo sapiens 11.0 11.0 1 PMID:3646070 -3.4.21.37 n-methoxysuccinyl-ala-ala-pro-val-4-nitroanilide homo sapiens 6.71 6.71 1 PMID:18295791 -3.4.21.37 n-succinyl-ala-ala-ala 4-nitroanilide equus caballus 3.4 2.95 2 PMID:7516152 -3.4.21.37 n-succinyl-ala-ala-ala 4-nitroanilide homo sapiens 2.1 1.4 2 PMID:312290;PMID:7516152 -3.4.21.37 n-succinyl-ala-ala-val 4-nitroanilide equus caballus 6.2 3.9000000000000004 2 PMID:7516152 -3.4.21.37 n-succinyl-ala-ala-val 4-nitroanilide homo sapiens 3.1 3.1 1 PMID:7516152 -3.4.21.37 tert-butyloxycarbonyl-ala-4-nitrophenyl ester equus caballus 26.1 19.05 2 PMID:7516152 -3.4.21.37 tert-butyloxycarbonyl-l-val-4-nitrophenyl ester equus caballus 4.5 3.5 2 PMID:7516152 -3.4.21.37 tosyl-ala-3-hydroxy-5-phenylpyrrole homo sapiens 4800.0 2170.0 6 PMID:7487054 -3.4.21.37 tosyl-ala-4-nitrophenol homo sapiens 120.0 120.0 1 PMID:7487054 -3.4.21.38 benzyloxycarbonyl-ala-arg-sch2c6h5 homo sapiens 15.0 15.0 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-ala-arg-sch2ch(ch3)2 homo sapiens 14.0 14.0 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-ala-phe-arg-4-nitroanilide homo sapiens 34.6 34.6 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-arg-sch2ch(ch3)2 homo sapiens 22.0 22.0 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-asn-gly-arg-4-nitroanilide homo sapiens 23.0 20.5 2 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-asn-phe-arg-4-nitroanilide homo sapiens 23.0 23.0 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-glu-arg-sch2ch(ch3)2 homo sapiens 9.2 9.2 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-gly-arg-sch2ch(ch3)2 homo sapiens 43.0 43.0 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-lys-arg-sch2ch(ch3)2 homo sapiens 15.0 15.0 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-lys-gly-arg-4-nitroanilide homo sapiens 25.0 25.0 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-lys-phe-arg-4-nitroanilide homo sapiens 23.0 23.0 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-met-arg-sch2ch(ch3)2 homo sapiens 2.5 2.5 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-phe-arg-sch2ch(ch3)2 homo sapiens 8.3 8.3 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-phe-gly-arg-4-nitroanilide homo sapiens 14.0 14.0 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-pro-arg-sch2ch(ch3)2 homo sapiens 8.3 8.3 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-pro-gly-arg-4-nitroanilide homo sapiens 9.2 9.2 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-ser-arg-sch2ch(ch3)2 homo sapiens 13.0 13.0 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-ser-phe-arg-4-nitroanilide homo sapiens 28.0 28.0 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-thr-arg-sch2ch(ch3)2 homo sapiens 11.0 11.0 1 PMID:6370301 -3.4.21.38 benzyloxycarbonyl-val-arg-sch2ch(ch3)2 homo sapiens 17.0 17.0 1 PMID:6370301 -3.4.21.38 d-pro-phe-arg-4-nitroanilide homo sapiens 24.44 16.475 6 PMID:31205020;PMID:3237092 -3.4.21.38 nalpha-benzoyl-ile-glu(-or)-gly-arg-4-nitroanilide homo sapiens 23.0 23.0 1 PMID:3237092 -3.4.21.38 prekallikrein homo sapiens 0.73 0.73 1 PMID:28069606 -3.4.21.38 pro-phe-arg-4-methylcoumarin 7-amide homo sapiens 1.9 1.9 1 PMID:3237092 -3.4.21.38 s-2302 homo sapiens 11.7 11.7 1 PMID:28069606 -3.4.21.38 tert-butyloxycarbonyl-arg-sch2c6h5 homo sapiens 2.9 2.9 1 PMID:6370301 -3.4.21.38 tert-butyloxycarbonyl-arg-sch2ch(ch3)2 homo sapiens 9.2 9.2 1 PMID:6370301 -3.4.21.39 ala-ala-pro-leu-4-nitroanilide cavia porcellus 0.93 0.93 1 PMID:18353771 -3.4.21.39 ala-ala-pro-leu-4-nitroanilide homo sapiens 19.3 19.3 1 PMID:18353771 -3.4.21.39 ala-ala-pro-met-4-nitroanilide cavia porcellus 0.098 0.098 1 PMID:18353771 -3.4.21.39 ala-ala-pro-met-4-nitroanilide homo sapiens 23.0 23.0 1 PMID:18353771 -3.4.21.39 ala-ala-pro-phe-4-nitroanilide cavia porcellus 0.028 0.028 1 PMID:18353771 -3.4.21.39 ala-ala-pro-phe-4-nitroanilide homo sapiens 143.0 143.0 1 PMID:18353771 -3.4.21.39 angiotensin i homo sapiens 143.0 140.0 3 PMID:10082988;PMID:9352125 -3.4.21.39 angiotensin i mesocricetus auratus 149.0 149.0 1 PMID:8632712 -3.4.21.39 angiotensin ii mesocricetus auratus 1.19 1.19 1 PMID:8632712 -3.4.21.39 big endothelin-1 homo sapiens 25.6 25.15 2 PMID:10082988 -3.4.21.39 drvwihpfhl homo sapiens 160.0 160.0 1 PMID:8226889 -3.4.21.39 drvwihpwhl homo sapiens 210.0 210.0 1 PMID:8226889 -3.4.21.39 drvyihplhl homo sapiens 46.0 46.0 1 PMID:8226889 -3.4.21.39 h2n(ch2)5co-ala-ala-pro-phe-4-nitroanilide rattus norvegicus 13.0 13.0 1 PMID:7006692 -3.4.21.39 methoxysuccinyl-ala-ala-pro-phe-4-nitroanilide rattus norvegicus 10.0 10.0 1 PMID:7006692 -3.4.21.39 succinyl-ala-ala-pro-leu-4-nitroanilide homo sapiens 6.7 6.7 1 PMID:8226889 -3.4.21.39 succinyl-ala-ala-pro-met-4-nitroanilide homo sapiens 2.5 2.5 1 PMID:8226889 -3.4.21.39 succinyl-ala-ala-pro-phe-4-nitroanilide homo sapiens 65.0 41.25 2 PMID:15163313;PMID:8226889 -3.4.21.39 succinyl-ala-ala-pro-phe-4-nitroanilide mus musculus 2.84 2.33 5 PMID:8363563 -3.4.21.39 succinyl-ala-pro-phe-4-nitroanilide homo sapiens 51.0 51.0 1 PMID:3893542 -3.4.21.39 succinyl-ala-pro-phe-4-nitroanilide rattus norvegicus 38.0 38.0 1 PMID:3893542 -3.4.21.39 succinyl-ala-val-pro-phe-4-nitroanilide rattus norvegicus 17.0 17.0 1 PMID:3893542 -3.4.21.39 succinyl-epsilon-(2-picolinyl)lys-pro-phe-4-nitroanilide rattus norvegicus 4.7 4.7 1 PMID:3893542 -3.4.21.39 succinyl-epsilon-(2-picolinyl)lys-val-pro-phe-4-nitroanilide homo sapiens 480.0 480.0 1 PMID:3893542 -3.4.21.39 succinyl-epsilon-(2-picolinyl)lys-val-pro-phe-4-nitroanilide rattus norvegicus 86.0 86.0 1 PMID:3893542 -3.4.21.39 succinyl-gln-pro-phe-4-nitroanilide homo sapiens 86.0 71.0 2 PMID:3893542 -3.4.21.39 succinyl-glu-pro-phe-4-nitroanilide homo sapiens 61.0 61.0 1 PMID:3893542 -3.4.21.39 succinyl-glu-pro-phe-4-nitroanilide rattus norvegicus 9.2 9.2 1 PMID:3893542 -3.4.21.39 succinyl-glu-val-pro-phe-4-nitroanilide homo sapiens 68.0 68.0 1 PMID:3893542 -3.4.21.39 succinyl-glu-val-pro-phe-4-nitroanilide rattus norvegicus 53.0 53.0 1 PMID:3893542 -3.4.21.39 succinyl-l-ala-l-ala-l-pro-l-phe-4-nitroanilide homo sapiens 3.6 3.05 2 PMID:25131858 -3.4.21.39 succinyl-l-ala-l-ala-l-pro-l-phe-thiobenzyl ester homo sapiens 17.8 15.2 2 PMID:25131858 -3.4.21.39 succinyl-leu-pro-phe-4-nitroanilide homo sapiens 77.0 77.0 1 PMID:3893542 -3.4.21.39 succinyl-leu-pro-phe-4-nitroanilide rattus norvegicus 37.0 37.0 1 PMID:3893542 -3.4.21.39 succinyl-leu-val-pro-phe-4-nitroanilide homo sapiens 79.0 79.0 1 PMID:3893542 -3.4.21.39 succinyl-leu-val-pro-phe-4-nitroanilide rattus norvegicus 19.0 19.0 1 PMID:3893542 -3.4.21.39 succinyl-lys-pro-phe-4-nitroanilide homo sapiens 14.0 14.0 1 PMID:3893542 -3.4.21.39 succinyl-lys-pro-phe-4-nitroanilide rattus norvegicus 32.0 32.0 1 PMID:3893542 -3.4.21.39 succinyl-lys-val-pro-phe-4-nitroanilide homo sapiens 58.0 58.0 1 PMID:3893542 -3.4.21.39 succinyl-lys-val-pro-phe-4-nitroanilide rattus norvegicus 66.0 66.0 1 PMID:3893542 -3.4.21.39 succinyl-met-pro-phe-4-nitroanilide homo sapiens 100.0 100.0 1 PMID:3893542 -3.4.21.39 succinyl-met-pro-phe-4-nitroanilide rattus norvegicus 25.0 25.0 1 PMID:3893542 -3.4.21.39 succinyl-met-val-pro-phe-4-nitroanilide canis lupus familiaris 30.0 30.0 1 PMID:3893542 -3.4.21.39 succinyl-met-val-pro-phe-4-nitroanilide homo sapiens 53.0 53.0 1 PMID:3893542 -3.4.21.39 succinyl-met-val-pro-phe-4-nitroanilide rattus norvegicus 25.0 25.0 1 PMID:3893542 -3.4.21.39 succinyl-phe-ala-phe-4-nitroanilide homo sapiens 10.0 10.0 1 PMID:3893542 -3.4.21.39 succinyl-phe-ala-phe-4-nitroanilide rattus norvegicus 7.1 7.1 1 PMID:3893542 -3.4.21.39 succinyl-phe-epsilon-(2-picolinyl)lys-4-nitroanilide rattus norvegicus 23.0 23.0 1 PMID:3893542 -3.4.21.39 succinyl-phe-gln-phe-4-nitroanilide homo sapiens 3.9 3.9 1 PMID:3893542 -3.4.21.39 succinyl-phe-gln-phe-4-nitroanilide rattus norvegicus 25.0 25.0 1 PMID:3893542 -3.4.21.39 succinyl-phe-glu-phe-4-nitroanilide homo sapiens 8.4 8.4 1 PMID:3893542 -3.4.21.39 succinyl-phe-glu-phe-4-nitroanilide rattus norvegicus 0.9 0.9 1 PMID:3893542 -3.4.21.39 succinyl-phe-leu-phe-4-nitroanilide homo sapiens 7.5 7.5 1 PMID:3893542 -3.4.21.39 succinyl-phe-leu-phe-4-nitroanilide rattus norvegicus 19.0 18.0 2 PMID:3893542;PMID:7006692 -3.4.21.39 succinyl-phe-lys-phe-4-nitroanilide rattus norvegicus 18.0 18.0 1 PMID:3893542 -3.4.21.39 succinyl-phe-met-phe-4-nitroanilide homo sapiens 5.9 5.9 1 PMID:3893542 -3.4.21.39 succinyl-phe-met-phe-4-nitroanilide rattus norvegicus 8.2 8.2 1 PMID:3893542 -3.4.21.39 succinyl-phe-pro-phe-4-nitroanilide rattus norvegicus 28.0 24.0 3 PMID:3893542;PMID:7006692 -3.4.21.39 succinyl-phe-pro-thr-phe-4-nitroanilide rattus norvegicus 19.0 15.0 2 PMID:7006692 -3.4.21.39 succinyl-phe-ser-phe-4-nitroanilide homo sapiens 6.2 6.2 1 PMID:3893542 -3.4.21.39 succinyl-phe-ser-phe-4-nitroanilide rattus norvegicus 5.4 5.4 1 PMID:3893542 -3.4.21.39 succinyl-phe-thr-phe-4-nitroanilide homo sapiens 10.0 10.0 1 PMID:3893542 -3.4.21.39 succinyl-phe-thr-phe-4-nitroanilide rattus norvegicus 9.3 9.3 1 PMID:3893542 -3.4.21.39 succinyl-phe-val-phe-4-nitroanilide homo sapiens 4.0 4.0 1 PMID:3893542 -3.4.21.39 succinyl-phe-val-phe-4-nitroanilide rattus norvegicus 15.0 15.0 1 PMID:3893542 -3.4.21.39 succinyl-phe-val-pro-phe-4-nitroanilide canis lupus familiaris 33.0 33.0 1 PMID:3893542 -3.4.21.39 succinyl-phe-val-pro-phe-4-nitroanilide homo sapiens 56.0 56.0 1 PMID:3893542 -3.4.21.39 succinyl-phe-val-pro-phe-4-nitroanilide rattus norvegicus 24.0 24.0 1 PMID:3893542 -3.4.21.39 succinyl-ser-pro-phe-4-nitroanilide homo sapiens 38.0 38.0 1 PMID:3893542 -3.4.21.39 succinyl-ser-pro-phe-4-nitroanilide rattus norvegicus 20.0 20.0 1 PMID:3893542 -3.4.21.39 succinyl-thr-pro-phe-4-nitroanilide canis lupus familiaris 65.0 65.0 1 PMID:3893542 -3.4.21.39 succinyl-thr-pro-phe-4-nitroanilide homo sapiens 120.0 120.0 1 PMID:3893542 -3.4.21.39 succinyl-thr-pro-phe-4-nitroanilide rattus norvegicus 38.0 38.0 1 PMID:3893542 -3.4.21.39 succinyl-val-pro-leu-4-nitroanilide homo sapiens 21.0 21.0 1 PMID:3893542;PMID:8226889 -3.4.21.39 succinyl-val-pro-leu-4-nitroanilide rattus norvegicus 13.0 13.0 1 PMID:3893542 -3.4.21.39 succinyl-val-pro-met-4-nitroanilide homo sapiens 8.7 4.949999999999999 2 PMID:3893542;PMID:8226889 -3.4.21.39 succinyl-val-pro-met-4-nitroanilide rattus norvegicus 5.0 5.0 1 PMID:3893542 -3.4.21.39 succinyl-val-pro-phe-4-nitroanilide homo sapiens 75.0 75.0 1 PMID:3893542;PMID:8226889 -3.4.21.39 succinyl-val-pro-phe-4-nitroanilide rattus norvegicus 57.0 57.0 1 PMID:3893542 -3.4.21.39 succinyl-val-pro-pro-phe-sch2c6h5 homo sapiens 400.0 400.0 1 PMID:3893542 -3.4.21.39 succinyl-val-pro-pro-phe-sch2c6h5 rattus norvegicus 130.0 130.0 1 PMID:3893542 -3.4.21.39 succinyl-val-pro-trp-4-nitroanilide rattus norvegicus 8.4 7.0 2 PMID:3893542 -3.4.21.39 succinyl-val-pro-tyr-4-nitroanilide homo sapiens 19.0 19.0 1 PMID:3893542 -3.4.21.39 succinyl-val-pro-tyr-4-nitroanilide rattus norvegicus 5.5 5.5 1 PMID:3893542 -3.4.21.4 2-aminobenzoyl-aagrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 33000.0 33000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-adgrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 3800.0 3800.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aegrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 13300.0 13300.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-afgrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 30000.0 30000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-agergagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 330000.0 330000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggraagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 240000.0 240000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggrdagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 123000.0 123000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggreagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 133000.0 133000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggrfagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 217000.0 217000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 200000.0 200000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggrhagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 183000.0 183000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggriagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 133000.0 133000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggrkagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 230000.0 230000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggrlagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 138000.0 138000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggrmagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 200000.0 200000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggrnagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 300000.0 300000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggrqagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 230000.0 230000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggrsagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 400000.0 400000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggrtagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 200000.0 200000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggrvagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 133000.0 133000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aggryagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 167000.0 167000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aghrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 630000.0 630000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-agkrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 117000.0 117000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aglrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 130000.0 130000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-agnrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 400000.0 400000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-agsrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 910000.0 910000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-agtrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 410000.0 410000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-ahgrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 26700.0 26700.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aigrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 20000.0 20000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-akgrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 41000.0 41000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-algrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 33000.0 33000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-amgrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 41000.0 41000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-angrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 16300.0 16300.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aqgrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 50000.0 50000.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-asgrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 31700.0 31700.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-atgrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 16500.0 16500.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-avgrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 21700.0 21700.0 1 PMID:11779198 -3.4.21.4 2-aminobenzoyl-aygrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 31700.0 31700.0 1 PMID:11779198 -3.4.21.4 abz-erfk-eddnp colossoma macropomum 17.3 17.3 1 PMID:20438707 -3.4.21.4 abz-frfk-eddnp colossoma macropomum 8.87 8.87 1 PMID:20438707 -3.4.21.4 abz-grfk-eddnp colossoma macropomum 31.94 31.94 1 PMID:20438707 -3.4.21.4 abz-hrfk-eddnp colossoma macropomum 21.07 21.07 1 PMID:20438707 -3.4.21.4 abz-krfk-eddnp colossoma macropomum 53.23 53.23 1 PMID:20438707 -3.4.21.4 abz-lrfk-eddnp colossoma macropomum 53.23 53.23 1 PMID:20438707 -3.4.21.4 abz-nrfk-eddnp colossoma macropomum 30.61 30.61 1 PMID:20438707 -3.4.21.4 abz-qrfk-eddnp colossoma macropomum 12.64 12.64 1 PMID:20438707 -3.4.21.4 abz-rdfk-eddnp colossoma macropomum 2.33 2.33 1 PMID:20438707 -3.4.21.4 abz-refk-eddnp colossoma macropomum 7.49 7.49 1 PMID:20438707 -3.4.21.4 abz-rgfk-eddnp colossoma macropomum 9.15 9.15 1 PMID:20438707 -3.4.21.4 abz-rhfk-eddnp colossoma macropomum 8.32 8.32 1 PMID:20438707 -3.4.21.4 abz-rnfk-eddnp colossoma macropomum 16.63 16.63 1 PMID:20438707 -3.4.21.4 abz-rpfk-eddnp colossoma macropomum 0.1 0.1 1 PMID:20438707 -3.4.21.4 abz-rqfk-eddnp colossoma macropomum 13.31 13.31 1 PMID:20438707 -3.4.21.4 abz-rrfk-eddnp colossoma macropomum 26.61 26.61 1 PMID:20438707 -3.4.21.4 abz-rsfk-eddnp colossoma macropomum 16.63 16.63 1 PMID:20438707 -3.4.21.4 abz-rtfk-eddnp colossoma macropomum 18.3 18.3 1 PMID:20438707 -3.4.21.4 abz-rvfk-eddnp colossoma macropomum 4.59 4.59 1 PMID:20438707 -3.4.21.4 abz-ryfk-eddnp colossoma macropomum 10.65 10.65 1 PMID:20438707 -3.4.21.4 abz-vrfk-eddnp colossoma macropomum 46.57 46.57 1 PMID:20438707 -3.4.21.4 abz-wrfk-eddnp colossoma macropomum 6.32 6.32 1 PMID:20438707 -3.4.21.4 abz-yrfk-eddnp colossoma macropomum 27.72 27.72 1 PMID:20438707 -3.4.21.4 acetyl-ala-val-(l-alpha-aminobutyryl)-pro-arg(no2)-4-nitroanilide bos taurus 1.4 1.4 1 PMID:11478806 -3.4.21.4 acetyl-ala-val-(l-alpha-aminobutyryl)-pro-arg-4-nitroanilide bos taurus 23.0 23.0 1 PMID:11478806 -3.4.21.4 acetyl-ala-val-(l-alpha-aminobutyryl)-pro-lys-4-nitroanilide bos taurus 19.0 19.0 1 PMID:11478806 -3.4.21.4 acetyl-ala-val-(l-alpha-aminobutyryl)-pro-n-omega-hydroxy-l-arginine-4-nitroanilide bos taurus 3.2 3.2 1 PMID:11478806 -3.4.21.4 acetyl-ala-val-(l-alpha-aminobutyryl)-pro-phe(p-cn)-4-nitroanilide bos taurus 0.7 0.7 1 PMID:11478806 -3.4.21.4 acetyl-ala-val-(l-alpha-aminobutyryl)-pro-phe(p-nh2)-4-nitroanilide bos taurus 5.1 5.1 1 PMID:11478806 -3.4.21.4 alpha-n-benzyloxycarbonyl-lys-thiobenzyl ester rattus norvegicus 112.0 112.0 1 PMID:7857928 -3.4.21.4 alpha-n-p-tosyl-l-arginine methyl ester lutjanus vitta 112.0 112.0 1 * -3.4.21.4 benzoyl-arg 4-nitroanilide engraulis japonicus 3.7 2.94 3 PMID:11330348 -3.4.21.4 benzoyl-arg ethyl ester bos taurus 26.6 13.42 2 PMID:4472038 -3.4.21.4 benzoyl-arg ethyl ester engraulis japonicus 42.9 21.599999999999998 2 PMID:11330348 -3.4.21.4 benzoyl-arg-p-nitroanilide bos taurus 1.13 1.13 1 PMID:16879823 -3.4.21.4 benzoyl-arg-p-nitroanilide gadus morhua 3.44 3.44 1 PMID:16879823 -3.4.21.4 benzoyl-dl-arg-4-nitroanilide cirrhinus mrigala 6.17 6.17 1 PMID:25577096 -3.4.21.4 benzoyl-dl-arg-4-nitroanilide oreochromis niloticus 23.8 23.8 1 PMID:25005977 -3.4.21.4 benzoyl-dl-arg-4-nitroanilide pterygoplichthys disjunctivus 1.46 1.46 1 PMID:23790871 -3.4.21.4 benzoyl-dl-arg-7-amido-4-methylcoumarin homo sapiens 0.25 0.25 1 PMID:19271729 -3.4.21.4 benzoyl-dl-arg-p-nitroanilide homo sapiens 1.33 1.33 1 PMID:19271729 -3.4.21.4 benzoyl-l-arginine-p-nitroanilide bos taurus 2.43 0.85 4 PMID:17827714 -3.4.21.4 benzoyl-l-arginine-p-nitroanilide oncorhynchus keta 7.7 2.935 14 PMID:17827714 -3.4.21.4 benzyloxycarbonyl-gln-arg-arg-7-amido-4-methylcoumarin channa argus 76.0 76.0 1 PMID:22155550 -3.4.21.4 benzyloxycarbonyl-glu-arg-arg-7-amido-4-methylcoumarin channa argus 92.0 92.0 1 PMID:22155550 -3.4.21.4 benzyloxycarbonyl-gly-pro-arg-4-methylcoumarin 7-amide rattus norvegicus 58.3 58.3 1 PMID:7857928 -3.4.21.4 benzyloxycarbonyl-gly-pro-arg-p-nitroanilide gadus morhua 172.8 86.405 2 PMID:16879823 -3.4.21.4 benzyloxycarbonyl-l-glutaminyl-l-arginyl-l-arginine-4-methylcoumaryl-7-amide lateolabrax japonicus 42.99 42.065 2 PMID:21515400 -3.4.21.4 benzyloxycarbonyl-l-leucyl-l-arginyl-l-arginine-4-methylcoumaryl-7-amide lateolabrax japonicus 14.85 9.75 2 PMID:21515400 -3.4.21.4 benzyloxycarbonyl-l-leucyl-l-lysyl-l-arginine-4-methylcoumaryl-7-amide lateolabrax japonicus 12.19 8.805 2 PMID:21515400 -3.4.21.4 benzyloxycarbonyl-l-phenylalaninyl-l-seryl-l-arginine-4-methylcoumaryl-7-amide lateolabrax japonicus 72.08 69.935 2 PMID:21515400 -3.4.21.4 benzyloxycarbonyl-l-valyl-l-leucyl-l-lysine-4-methylcoumaryl-7-amide lateolabrax japonicus 8.07 5.635 2 PMID:21515400 -3.4.21.4 benzyloxycarbonyl-l-valyl-l-prolyl-l-arginine-4-methylcoumaryl-7-amide lateolabrax japonicus 25.75 15.629999999999999 2 PMID:21515400 -3.4.21.4 benzyloxycarbonyl-leu-arg-arg-7-amido-4-methylcoumarin channa argus 72.0 72.0 1 PMID:22155550 -3.4.21.4 benzyloxycarbonyl-leu-lys-arg-7-amido-4-methylcoumarin channa argus 80.0 80.0 1 PMID:22155550 -3.4.21.4 benzyloxycarbonyl-lys methyl ester bos taurus 80.0 40.355 2 PMID:4472038 -3.4.21.4 benzyloxycarbonyl-lys p-nitrophenyl ester bos taurus 82.0 52.5 2 PMID:4472038 -3.4.21.4 benzyloxycarbonyl-phe-ser-arg-7-amido-4-methylcoumarin channa argus 148.0 148.0 1 PMID:22155550 -3.4.21.4 benzyloxycarbonylglycyl-l-prolyl-l-arginine-4-methylcoumaryl-7-amide streptomyces griseus 33.0 33.0 1 PMID:21767670 -3.4.21.4 benzyloxycarbonylglycyl-l-prolyl-l-arginine-4-methylcoumaryl-7-amide streptomyces omiyaensis 279.5 279.5 1 PMID:21767670 -3.4.21.4 enhanced green fluorescent protein-t1 homo sapiens 0.26 0.26 1 PMID:19271729 -3.4.21.4 enhanced green fluorescent protein-t1nb homo sapiens 0.85 0.85 1 PMID:19271729 -3.4.21.4 factor xa streptomyces griseus 124.0 124.0 1 PMID:16503653 -3.4.21.4 fitc-casein sus scrofa 0.48 0.435 8 PMID:15880790 -3.4.21.4 gergffytpkt bos taurus 0.313 0.313 1 PMID:22982989 -3.4.21.4 gergffytpktrr bos taurus 4.15 4.15 1 PMID:22982989 -3.4.21.4 human m-proinsulin bos taurus 11.65 11.65 1 PMID:22982989 -3.4.21.4 insulin bos taurus 0.14 0.14 1 PMID:22982989 -3.4.21.4 l-phe-l-val-l-ile-(3-carbamoyl-4-nitrophenyl)-l-arg-amide bos taurus 3.2 3.2 1 PMID:15158459 -3.4.21.4 l-phe-l-val-l-ile-n-(3-carbamoyl-4-nitrophenyl)-l-arg-amide bos taurus 4.4 4.4 1 PMID:15158459 -3.4.21.4 l-phe-l-val-l-pro-n-(3-carbamoyl-4-nitrophenyl)-l-arg-amide bos taurus 27.4 27.4 1 PMID:15158459 -3.4.21.4 l-phe-l-val-l-pro-n-(3-carbamoyl-4-nitrophenyl)-l-lys-amide bos taurus 4.0 4.0 1 PMID:15158459 -3.4.21.4 m-diarginyl insulin bos taurus 1.1 1.1 1 PMID:22982989 -3.4.21.4 m-insulin bos taurus 0.14 0.14 1 PMID:22982989 -3.4.21.4 meosuc-ala-ala-ala-arg 4-nitroanilide gadus morhua 30.5 30.5 1 PMID:19913635 -3.4.21.4 meosuc-ala-ala-arg 4-nitroanilide gadus morhua 33.6 33.6 1 PMID:19913635 -3.4.21.4 meosuc-ala-arg 4-nitroanilide gadus morhua 24.9 24.9 1 PMID:19913635 -3.4.21.4 n-alpha-benzoyl-l-arg ethyl ester bos taurus 12.3 11.4 2 PMID:15317487 -3.4.21.4 n-alpha-benzoyl-l-arg-p-nitroanilide saccharopolyspora erythraea 5.73 5.73 1 PMID:19231893 -3.4.21.4 n-alpha-benzoyl-l-arg-p-nitroanilide sus scrofa 2.46 2.46 1 PMID:19231893 -3.4.21.4 n-alpha-benzoyl-l-arginine-p-nitroanilide euphausia pacifica 0.98 0.9099999999999999 2 PMID:17987272 -3.4.21.4 n-alpha-benzoyl-l-lys-4-nitroanilide saccharopolyspora erythraea 1.04 1.04 1 PMID:19231893 -3.4.21.4 n-alpha-benzoyl-l-lys-4-nitroanilide sus scrofa 0.56 0.56 1 PMID:19231893 -3.4.21.4 n-alpha-p-tosyl-l-arginine methyl ester thunnus albacares 80.0 73.35 2 PMID:16500127 -3.4.21.4 n-benzoyl-dl-arg-4-nitroanilide bos taurus 0.8 0.8 1 PMID:15158459 -3.4.21.4 n-benzoyl-dl-arginine 4-nitroanilide boops boops 1.56 1.56 1 PMID:19898990 -3.4.21.4 n-benzoyl-dl-arginine 4-nitroanilide gadus morhua 1.34 1.34 1 PMID:19913635 -3.4.21.4 n-benzoyl-dl-arginine 4-nitroanilide lutjanus vitta 4.71 4.71 1 * -3.4.21.4 n-benzoyl-dl-arginine 4-nitroanilide mustelus mustelus 2.62 2.62 1 PMID:20405833 -3.4.21.4 n-benzoyl-dl-arginine 4-nitroanilide sepia officinalis 2.32 2.32 1 * -3.4.21.4 n-benzoyl-dl-arginine-4-nitroanilide streptomyces griseus 3.8 3.8 1 PMID:18261455 -3.4.21.4 n-benzoyl-l-arginine-p-nitroanilide bos taurus 6.1 6.1 1 PMID:18308489 -3.4.21.4 n-benzoyl-l-isoleucyl-l-glutamyl-glycyl-l-arginine-4-nitroanilide homo sapiens 70.5 32.7 3 PMID:19249338 -3.4.21.4 n-benzyloxycarbonyl-gly-pro-arg 4-nitroanilide gadus morhua 54.5 51.0 4 PMID:19913635 -3.4.21.4 n-benzyloxycarbonyl-gly-pro-arg-4-nitroanilide homo sapiens 154.0 133.5 4 PMID:32014997 -3.4.21.4 n-benzyloxycarbonyl-l-lysine benzyl ester bos taurus 84.0 46.0 2 PMID:4472038 -3.4.21.4 n-carbobenzyloxy-gly-pro-arg-p-nitroanilide homo sapiens 158.0 158.0 1 PMID:17436323 -3.4.21.4 nalpha-4-tosyl-l-arginine methyl ester albatrossia pectoralis 210.0 210.0 1 PMID:19585993 -3.4.21.4 nalpha-4-tosyl-l-arginine methyl ester mustelus mustelus 59.15 59.15 1 PMID:20405833 -3.4.21.4 nalpha-benzoyl-dl-arg-p-nitroanilide gallus gallus 1.0 0.473 3 PMID:10480246 -3.4.21.4 nalpha-benzoyl-dl-arginine 4-nitroanilide balistes capriscus 2.76 2.76 1 * -3.4.21.4 nalpha-benzoyl-dl-arginine-4-nitroanilide sardinella aurita 5.76 2.24 3 PMID:20711672 -3.4.21.4 nalpha-benzoyl-l-arg-4-nitroanilide sardinops caeruleus 2.12 2.12 1 * -3.4.21.4 nalpha-benzoyl-l-arginine ethyl ester bos taurus 16.5 16.5 1 PMID:22982989 -3.4.21.4 nalpha-benzyloxycarbonyl-lys-p-nitrophenyl ester bos taurus 0.13 0.052 5 PMID:3080421 -3.4.21.4 nalpha-p-tosyl-l-arg methyl ester thunnus tonggol 200.0 200.0 1 PMID:16848554 -3.4.21.4 o-aminobenzoyl-aagrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 1.2 1.2 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aagrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.54 0.54 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aagrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.0067 0.0067 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-adgrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.013 0.013 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-adgrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.0014 0.0014 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aegrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 0.064 0.064 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aegrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.08 0.08 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aegrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.0045 0.0045 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-afgrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 1.2 1.2 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-afgrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.0072 0.0072 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agargagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 52.0 52.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agargagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.74 0.74 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agargagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00022 0.00022 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agdrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 5.9 5.9 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agdrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.03 0.03 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agdrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 4e-05 4e-05 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agergagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 1.4 1.4 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agergagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.09 0.09 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agergagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 4e-05 4e-05 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agfrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 26.0 26.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agfrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.43 0.43 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agfrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00022 0.00022 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggkgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 1.4 1.4 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggkgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 1.7 1.7 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggkgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 630.0 630.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggkgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 4e-05 4e-05 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 0.9 0.9 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 2.7 2.7 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgagq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 820.0 820.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00011 0.00011 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgdgq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.00014 0.00014 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgegq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.00013 0.00013 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgfgq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.0034 0.0034 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgggq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.00029 0.00029 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrghgq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.00063 0.00063 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgigq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.0007 0.0007 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgkgq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.00043 0.00043 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrglgq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.00068 0.00068 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgmgq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.00063 0.00063 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgngq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.00027 0.00027 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgqgq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.00015 0.00015 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgsgq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.00034 0.00034 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgtgq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.0007 0.0007 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgvgq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.00078 0.00078 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aggrgygq-(2,4-dinitrophenyl-ethylene diamine) periplaneta americana 0.00145 0.00145 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aghrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 14.0 14.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aghrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.08 0.08 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aghrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00027 0.00027 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agirgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 12.0 12.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agirgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.38 0.38 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agirgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00022 0.00022 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agkrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 41.0 41.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agkrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.4 0.4 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agkrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00072 0.00072 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aglrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 19.0 19.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aglrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.26 0.26 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aglrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00017 0.00017 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agmrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 17.0 17.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agmrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.34 0.34 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agmrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00015 0.00015 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agnrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 140.0 140.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agnrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.08 0.08 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agnrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00017 0.00017 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agqrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 30.0 30.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agqrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.27 0.27 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agqrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00014 0.00014 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agsrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 14.0 14.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agsrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.16 0.16 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agsrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00011 0.00011 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agtrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.13 0.13 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agtrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00011 0.00011 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agvrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 26.0 26.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agvrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.4 0.4 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agvrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00015 0.00015 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agyrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 11.0 11.0 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agyrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.3 0.3 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-agyrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.00022 0.00022 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-ahgrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.004 0.004 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aigrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 0.37 0.37 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aigrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.26 0.26 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aigrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.0048 0.0048 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-akgrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 2.1 2.1 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-akgrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.17 0.17 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-akgrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.0055 0.0055 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-algrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 0.95 0.95 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-algrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.12 0.12 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-algrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.0052 0.0052 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-amgrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 1.9 1.9 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-amgrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.22 0.22 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-amgrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.005 0.005 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-angrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.83 0.83 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-angrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.0043 0.0043 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aqgrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 1.4 1.4 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aqgrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.19 0.19 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aqgrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.0068 0.0068 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-asgrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.013 0.013 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-asgrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.005 0.005 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-atgrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.006 0.006 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-avgrgagq-(2,4-dinitrophenyl-ethylene diamine) diatraea saccharalis 0.9 0.9 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-avgrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.57 0.57 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-avgrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.0047 0.0047 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aygrgagq-(2,4-dinitrophenyl-ethylene diamine) musca domestica 0.013 0.013 1 PMID:16431280 -3.4.21.4 o-aminobenzoyl-aygrgagq-(2,4-dinitrophenyl-ethylene diamine) tenebrio molitor 0.005 0.005 1 PMID:16431280 -3.4.21.4 suc-ala-ala-pro-arg-4-nitroanilide homo sapiens 223.0 155.0 4 PMID:32014997 -3.4.21.4 suc-ala-ala-pro-lys-4-nitroanilide homo sapiens 240.0 176.0 3 PMID:32014997 -3.4.21.4 succinyl-ala-ala-pro-arg-7-amido-4-methylcoumarin rattus norvegicus 91.0 91.0 1 PMID:15003560 -3.4.21.4 succinyl-ala-ala-pro-arg-p-nitroanilide rattus norvegicus 163.0 144.5 4 PMID:9739553 -3.4.21.4 succinyl-ala-ala-pro-leu-7-amido-4-methylcoumarin rattus norvegicus 0.000167 0.000167 1 PMID:15003560 -3.4.21.4 succinyl-ala-ala-pro-lys-7-amido-4-methylcoumarin rattus norvegicus 121.2 97.1 2 PMID:15003560 -3.4.21.4 succinyl-ala-ala-pro-lys-p-nitroanilide rattus norvegicus 74.0 61.5 4 PMID:9739553 -3.4.21.4 succinyl-ala-ala-pro-phe-7-amido-4-methylcoumarin rattus norvegicus 0.0063 0.0063 1 PMID:15003560 -3.4.21.4 succinyl-ala-ala-pro-tyr-7-amido-4-methylcoumarin rattus norvegicus 0.00067 0.00067 1 PMID:15003560 -3.4.21.4 tert-butoxycarbonyl-l-gln-l-ala-l-arg-7-amido-4-methylcoumarin homo sapiens 1.41 1.41 1 PMID:19271729 -3.4.21.4 tert-butyloxycarbonyl-phe-ser-arg-7-amido-4-methylcoumarin bos taurus 14.7 14.7 1 PMID:11154069 -3.4.21.4 tos-l-arg-ome bos taurus 139.0 89.1 4 PMID:17827714 -3.4.21.4 tos-l-arg-ome oncorhynchus keta 234.0 99.65 12 PMID:17827714 -3.4.21.4 tosyl-arg methyl ester bos taurus 76.0 38.85 2 PMID:4472038 -3.4.21.4 tosyl-gly-pro-arg-4-nitroanilide bos taurus 88.0 88.0 1 PMID:15044735 -3.4.21.4 tosyl-gly-pro-arg-4-nitroanilide salmon 30.4 29.2 2 PMID:15044735 -3.4.21.4 tosyl-gly-pro-arg-7-amido-4-methylcoumarin streptomyces griseus 2.7 1.7000000000000002 2 PMID:12885239 -3.4.21.4 z-gly-pro-arg-p-nitroanilide homo sapiens 88.2 69.1 2 PMID:18193894 -3.4.21.41 masp-3 k448q zymogen homo sapiens 0.0021 0.0021 1 PMID:23589288 -3.4.21.41 n-acetyl-arg methyl ester homo sapiens 18.3 18.3 1 PMID:469256 -3.4.21.41 n-acetyl-gly-lys methyl ester homo sapiens 12.5 12.5 1 PMID:469256 -3.4.21.41 zymogen c1s homo sapiens 0.0645 0.0645 1 PMID:23589288 -3.4.21.42 2-aminobenzoyl -ser-leu-gly-arg-lys-ile-gln-ile-lys(dinitrophenyl)-nh2 homo sapiens 0.00139 0.00139 1 PMID:14674770 -3.4.21.42 2-aminobenzoyl-glqralei-lys(dinitrophenol)-nh2 homo sapiens 1.14 1.14 1 PMID:25278939 -3.4.21.42 2-aminobenzoyl-gly-leu-gln-arg-ala-leu-glu-ile-lys(dinitrophenyl)-nh2 homo sapiens 0.00021 0.00021 1 PMID:14674770 -3.4.21.42 benzyloxycarbonyl-gly-leu-gln-arg-4-methylcoumaryl-7-amide homo sapiens 0.38 0.38 1 PMID:14674770 -3.4.21.42 benzyloxycarbonyl-ser-leu-gly-arg-4-methylcoumaryl-7-amide homo sapiens 0.5 0.5 1 PMID:14674770 -3.4.21.42 c1-inhibitor p4-p1 fragment homo sapiens 0.313 0.313 1 PMID:17709141 -3.4.21.42 c1-inhibitor p4-p4' fragment homo sapiens 0.0388 0.0388 1 PMID:17709141 -3.4.21.42 complement component c2 homo sapiens 5.6 5.35 2 PMID:16227207 -3.4.21.42 complement component c2 p4-p1 fragment homo sapiens 12.89 6.695 2 PMID:17709141 -3.4.21.42 complement component c2 p4-p4' fragment homo sapiens 0.069 0.069 1 PMID:17709141 -3.4.21.42 complement component c4 homo sapiens 6.7 5.4 3 PMID:16177097;PMID:16227207 -3.4.21.42 complement component c4 p4-p1 fragment homo sapiens 0.38 0.38 1 PMID:17709141 -3.4.21.42 complement component c4 p4-p4' fragment homo sapiens 0.015 0.015 1 PMID:17709141 -3.4.21.42 glqra homo sapiens 3.94e-05 3.94e-05 1 PMID:14674770 -3.4.21.42 glqraaei homo sapiens 0.000169 0.000169 1 PMID:14674770 -3.4.21.42 glqraeei homo sapiens 4.21e-05 4.21e-05 1 PMID:14674770 -3.4.21.42 glqrafei homo sapiens 0.00033 0.00033 1 PMID:14674770 -3.4.21.42 glqral homo sapiens 0.000683 0.000683 1 PMID:14674770 -3.4.21.42 glqralai homo sapiens 0.00274 0.00274 1 PMID:14674770 -3.4.21.42 glqrale homo sapiens 0.000319 0.000319 1 PMID:14674770 -3.4.21.42 glqralea homo sapiens 0.000392 0.000392 1 PMID:14674770 -3.4.21.42 glqralee homo sapiens 9.78e-05 9.78e-05 1 PMID:14674770 -3.4.21.42 glqralef homo sapiens 0.00022 0.00022 1 PMID:14674770 -3.4.21.42 glqraleh homo sapiens 0.000244 0.000244 1 PMID:14674770 -3.4.21.42 glqralei homo sapiens 0.000205 0.000205 1 PMID:14674770 -3.4.21.42 glqralek homo sapiens 0.000867 0.000867 1 PMID:14674770 -3.4.21.42 glqralel homo sapiens 9.78e-05 9.78e-05 1 PMID:14674770 -3.4.21.42 glqralem homo sapiens 0.000171 0.000171 1 PMID:14674770 -3.4.21.42 glqralep homo sapiens 0.000807 0.000807 1 PMID:14674770 -3.4.21.42 glqraleq homo sapiens 9.78e-05 9.78e-05 1 PMID:14674770 -3.4.21.42 glqralet homo sapiens 0.00044 0.00044 1 PMID:14674770 -3.4.21.42 glqralfi homo sapiens 0.00288 0.00288 1 PMID:14674770 -3.4.21.42 glqralhi homo sapiens 0.00821 0.00821 1 PMID:14674770 -3.4.21.42 glqralki homo sapiens 0.000136 0.000136 1 PMID:14674770 -3.4.21.42 glqralli homo sapiens 0.00296 0.00296 1 PMID:14674770 -3.4.21.42 glqralmi homo sapiens 0.00227 0.00227 1 PMID:14674770 -3.4.21.42 glqralpi homo sapiens 0.00244 0.00244 1 PMID:14674770 -3.4.21.42 glqralti homo sapiens 0.00279 0.00279 1 PMID:14674770 -3.4.21.42 glqramei homo sapiens 0.000119 0.000119 1 PMID:14674770 -3.4.21.42 glqrapei homo sapiens 1.89e-05 1.89e-05 1 PMID:14674770 -3.4.21.42 glqraqei homo sapiens 0.00232 0.000323 3 PMID:14674770 -3.4.21.42 glqratei homo sapiens 0.000147 0.000147 1 PMID:14674770 -3.4.21.42 glqrelei homo sapiens 2.05e-05 2.05e-05 1 PMID:14674770 -3.4.21.42 glqrflei homo sapiens 0.000155 0.000155 1 PMID:14674770 -3.4.21.42 glqrhlei homo sapiens 0.000415 0.000415 1 PMID:14674770 -3.4.21.42 glqrklei homo sapiens 7.62e-05 7.62e-05 1 PMID:14674770 -3.4.21.42 glqrllei homo sapiens 7.02e-05 7.02e-05 1 PMID:14674770 -3.4.21.42 glqrmlei homo sapiens 0.000239 0.000239 1 PMID:14674770 -3.4.21.42 glqrqlei homo sapiens 7.02e-05 7.02e-05 1 PMID:14674770 -3.4.21.42 glqrtlei homo sapiens 0.00155 0.00155 1 PMID:14674770 -3.4.21.42 n-benzoyl-phe-val-arg p-nitroanilide homo sapiens 5.7 5.7 1 PMID:17638 -3.4.21.42 n-benzyloxycarbonyl-lys p-nitrophenyl ester homo sapiens 20.8 20.8 1 PMID:869924 -3.4.21.42 tert-butyloxycarbonyl-tyr p-nitrophenyl ester homo sapiens 0.73 0.73 1 PMID:869924 -3.4.21.42 z-aglqr-7-amido-4-methylcoumarin homo sapiens 35.3 35.3 1 PMID:25278939 -3.4.21.42 z-lgr-7-amido-4-methylcoumarin homo sapiens 2.72 2.72 1 PMID:25278939 -3.4.21.43 complement component c5 homo sapiens 0.047 0.024 6 PMID:12878586;PMID:18204047 -3.4.21.46 benzyloxycarbonyl-lys-thiobenzyl ester homo sapiens 1.3 1.3 1 PMID:7592653 -3.4.21.47 complement component c3 homo sapiens 1.78 0.367 5 PMID:3638964 -3.4.21.47 complement component c5 homo sapiens 0.026 0.011 8 PMID:10640753;PMID:18204047 -3.4.21.47 t-butyloxycarbonyl-gly-l-leu-l-ala-l-arg-thiobenzyl ester homo sapiens 0.65 0.65 1 PMID:15068800 -3.4.21.48 acetyl-tyr ethyl ester saccharomyces cerevisiae 9.6 9.6 1 PMID:7028121 -3.4.21.48 benzoyl-tyr ethyl ester saccharomyces cerevisiae 2.1 2.1 1 PMID:7028121 -3.4.21.5 ac-gly-gly-val-arg-7-amido-4-methylcoumarin homo sapiens 1.2 1.2 1 PMID:10657126 -3.4.21.5 ac-leu-gly-val-arg-7-amido-4-methylcoumarin homo sapiens 15.6 15.6 1 PMID:10657126 -3.4.21.5 ac-nle-thr-leu-arg-7-amido-4-methylcoumarin homo sapiens 5.8 5.8 1 PMID:10657126 -3.4.21.5 ac-nle-thr-pro-arg-7-amido-4-methylcoumarin homo sapiens 45.0 45.0 1 PMID:10657126 -3.4.21.5 ac-val-thr-pro-arg-7-amido-4-methylcoumarin homo sapiens 30.8 30.8 1 PMID:10657126 -3.4.21.5 benzoyl-arg ethyl ester homo sapiens 17.8 15.2 5 PMID:6260805 -3.4.21.5 benzoyl-arg methyl ester homo sapiens 15.0 14.5 2 PMID:6260805 -3.4.21.5 d-phe-l-pipecolyl-l-arg-4-nitroanilide homo sapiens 77.8 56.5 5 PMID:2831192;PMID:7477382;PMID:9226718 -3.4.21.5 d-phe-pro-arg-4-nitroanilide homo sapiens 29.0 16.25 2 PMID:19846563 -3.4.21.5 d-phe-pro-lys-4-nitroanilide homo sapiens 12.0 10.0 2 PMID:19846563 -3.4.21.5 d-phe-pro-phe-4-nitroanilide homo sapiens 8.3 4.8500000000000005 2 PMID:19846563 -3.4.21.5 d-phenylalanyl-pipecolyl-l-arginine-4-nitroanilide homo sapiens 209.4 88.45 8 PMID:19589779;PMID:19640005 -3.4.21.5 di-l-glu-l-pro-l-arg-4-nitroanilide homo sapiens 278.6 240.3 4 PMID:19589779 -3.4.21.5 factor viii(341-376) peptide homo sapiens 6.0 4.62 2 PMID:12689334 -3.4.21.5 factor xiii homo sapiens 2.57 2.57 1 PMID:17286389 -3.4.21.5 factor xiii v34l mutant homo sapiens 22.9 22.9 1 PMID:17286389 -3.4.21.5 fc-[rfsrpql]-peg homo sapiens 0.01 0.01 1 PMID:20329721 -3.4.21.5 fibrinogen homo sapiens 5.9 5.9 1 PMID:8987977 -3.4.21.5 fibrinogen aalpha chain homo sapiens 57.0 57.0 1 PMID:7477382 -3.4.21.5 fibrinopeptide a homo sapiens 45.3 45.3 1 PMID:14722067 -3.4.21.5 glvprgvnl bos taurus 24.3 24.3 1 PMID:15065858 -3.4.21.5 gvvprgvnl bos taurus 5.8 5.8 1 PMID:15065858 -3.4.21.5 p-nitrophenyl-p'-(nbeta,n-butyl-nalpha-guanidino)benzoate homo sapiens 0.00102 0.00102 1 * -3.4.21.5 p-nitrophenyl-p'-(nbeta,n-hexyl-nalpha-guanidino)benzoate homo sapiens 0.00197 0.00197 1 * -3.4.21.5 p-nitrophenyl-p'-guanidinobenzoate homo sapiens 0.0018 0.0018 1 * -3.4.21.5 par1 peptide homo sapiens 146.0 146.0 1 PMID:14722067 -3.4.21.5 platelet thrombin receptor peptide homo sapiens 34.0 34.0 1 PMID:7477382 -3.4.21.5 protein c homo sapiens 0.65 0.35750000000000004 2 PMID:7477382;PMID:8987977 -3.4.21.5 spectrozyme-th homo sapiens 91.0 53.0 2 PMID:16428384 -3.4.21.5 spectrozyme-th mus musculus 32.0 32.0 2 PMID:16428384 -3.4.21.5 thrombin-activatable fibrinolysis inhibitor homo sapiens 0.315 0.315 1 PMID:19335449 -3.4.21.5 tosyl-arg ethyl ester homo sapiens 10.3 9.365 6 PMID:6260805 -3.4.21.5 tosyl-gly-pro-arg-4-nitroanilide homo sapiens 251.6 237.4 4 PMID:19589779 -3.4.21.5 tvelqglvprgvnl bos taurus 15.2 15.2 1 PMID:15065858 -3.4.21.5 tvelqgvvprgvnl bos taurus 6.2 6.2 1 PMID:15065858 -3.4.21.50 benzoyl-arg ethyl ester achromobacter lyticus 7.41 7.41 1 PMID:6168293 -3.4.21.50 benzoyl-lys methyl ester achromobacter lyticus 225.0 225.0 1 PMID:6168293;PMID:7845202 -3.4.21.50 benzoyl-lys-nh2 achromobacter lyticus 1.54 1.54 1 PMID:7845202 -3.4.21.50 benzoyl-lys-p-nitroanilide achromobacter lyticus 0.86 0.86 1 PMID:7845202 -3.4.21.50 lys-p-nitroanilide achromobacter lyticus 0.14 0.14 1 PMID:7845202 -3.4.21.50 n-benzoyl-l-orn methyl ester achromobacter lyticus 10.4 10.4 1 PMID:6168293;PMID:7845202 -3.4.21.50 n-tert-butyloxycarbonyl-ala-ala-lys-4-methylcoumarin 7-amide achromobacter lyticus 49.0 49.0 1 PMID:7845202 -3.4.21.50 n-tert-butyloxycarbonyl-ala-lys-4-methylcoumarin 7-amide achromobacter lyticus 32.9 32.9 1 PMID:7845202 -3.4.21.50 n-tert-butyloxycarbonyl-lys-4-methylcoumarin 7-amide achromobacter lyticus 3.02 3.02 1 PMID:7845202 -3.4.21.50 n-tosyl-gly-pro-lys-p-nitroanilide pseudomonas aeruginosa 59.0 59.0 1 PMID:3090046 -3.4.21.50 n-tosyl-l-arg methyl ester achromobacter lyticus 5.04 5.04 1 PMID:6168293;PMID:7845202 -3.4.21.50 n-tosyl-l-lys methyl ester achromobacter lyticus 570.0 570.0 1 PMID:6168293;PMID:7845202 -3.4.21.50 n-tosyl-l-lys methyl ester pseudomonas aeruginosa 282.0 282.0 1 PMID:3090046 -3.4.21.50 tert-butyloxycarbonyl-ala-ala-lys-7-amido-4-methylcoumarin achromobacter lyticus 98.0 98.0 1 PMID:11820934 -3.4.21.50 tert-butyloxycarbonyl-ala-lys-7-amido-4-methylcoumarin achromobacter lyticus 46.0 46.0 1 PMID:11820934 -3.4.21.50 tert-butyloxycarbonyl-lys-7-amido-4-methylcoumarin achromobacter lyticus 8.4 8.4 1 PMID:11820934 -3.4.21.50 tert-butyloxycarbonyl-val-leu-lys-7-amido-4-methylcoumarin achromobacter lyticus 93.0 93.0 1 PMID:11820934 -3.4.21.50 tosyl-gly-pro-lys-p-nitroanilide pseudomonas aeruginosa 59.0 59.0 1 PMID:3090046 -3.4.21.50 tosyl-lys methyl ester pseudomonas aeruginosa 282.0 282.0 1 PMID:3090046 -3.4.21.50 trypsinogen achromobacter lyticus 0.103 0.103 1 PMID:7845202 -3.4.21.53 atp escherichia coli 1.43 0.8 3 PMID:17975895;PMID:9490010 -3.4.21.53 atp salmonella enterica subsp. enterica serovar typhimurium 2.0 2.0 3 PMID:16819825 -3.4.21.53 bacteriophage lambda n-protein escherichia coli 1.0 1.0 1 PMID:2950089 -3.4.21.53 beta-galactosidase fragment 3-93 escherichia coli 0.84 0.84 1 PMID:18708584 -3.4.21.53 casein escherichia coli 0.0333 0.0333 1 PMID:2950089 -3.4.21.53 fluorogenic peptide s3 escherichia coli 7.7 7.7 1 PMID:12135363 -3.4.21.53 fretn 89-98 homo sapiens 6.63 6.63 1 PMID:28744459 -3.4.21.53 oxidized insulin b-chain escherichia coli 0.333 0.333 1 PMID:2950089 -3.4.21.53 y(3-no2)-rgit2-aminobuytric acid-sgrq-k(anthranilamide) salmonella enterica subsp. enterica serovar typhimurium 11.0 11.0 1 PMID:16819825 -3.4.21.53 y(3-no2)-rgitcsgrq-k(anthranilamide) salmonella enterica subsp. enterica serovar typhimurium 15.0 15.0 1 PMID:16819825 -3.4.21.53 y(3-no2)-rgitcyssgrq-k(anthranilamide) homo sapiens 5.9 5.9 1 PMID:16819825 -3.4.21.55 h-d-hexahydrotyrosyl-ala-arg 4-nitroanilide bitis gabonica 0.065 0.065 1 PMID:3522580 -3.4.21.55 h-d-phenylglycine-phe-arg 4-nitroanilide bitis gabonica 0.952 0.952 1 PMID:3522580 -3.4.21.55 h-d-pro-hexahydrotyrosyl-arg 4-nitroanilide bitis gabonica 0.248 0.248 1 PMID:3522580 -3.4.21.55 tosyl-gly-pro-arg 4-nitroanilide bitis gabonica 0.014 0.014 1 PMID:3522580 -3.4.21.55 tosyl-gly-pro-lys 4-nitroanilide bitis gabonica 0.204 0.204 1 PMID:3522580 -3.4.21.55 tosyl-l-arg methyl ester bitis gabonica 12.2 12.2 1 PMID:3522580 -3.4.21.57 nalpha-benzoyl-gly 4-nitroanilide spinacia oleracea 1.2 1.2 1 PMID:16664908 -3.4.21.57 nalpha-benzoyl-l-ala 4-nitroanilide spinacia oleracea 4.9 4.9 1 PMID:16664908 -3.4.21.57 nalpha-benzoyl-l-arg-4-nitroanilide spinacia oleracea 2.1 2.1 1 PMID:16664908 -3.4.21.57 nalpha-benzoyl-l-lys 4-nitroanilide spinacia oleracea 1.8 1.8 1 PMID:16664908 -3.4.21.57 nalpha-benzoyl-leu 4-nitroanilide spinacia oleracea 21.3 21.3 1 PMID:16664908 -3.4.21.57 nalpha-benzoyl-val 4-nitroanilide spinacia oleracea 6.1 6.1 1 PMID:16664908 -3.4.21.57 nalpha-carbobenzoxy-ala 4-nitrophenyl ester spinacia oleracea 94.0 94.0 1 PMID:16665073 -3.4.21.57 nalpha-carbobenzoxy-arg 4-nitrophenyl ester spinacia oleracea 43.0 43.0 1 PMID:16665073 -3.4.21.57 nalpha-carbobenzoxy-gly 4-nitrophenyl ester spinacia oleracea 21.0 21.0 1 PMID:16665073 -3.4.21.57 nalpha-carbobenzoxy-ile 4-nitrophenyl ester spinacia oleracea 140.0 140.0 1 PMID:16665073 -3.4.21.57 nalpha-carbobenzoxy-leu 4-nitrophenyl ester spinacia oleracea 430.0 430.0 1 PMID:16665073 -3.4.21.57 nalpha-carbobenzoxy-lys 4-nitrophenyl ester spinacia oleracea 45.0 45.0 1 PMID:16665073 -3.4.21.57 nalpha-carbobenzoxy-val 4-nitrophenyl ester spinacia oleracea 140.0 140.0 1 PMID:16665073 -3.4.21.59 ac-arg-asn-lys-5-amino-2-nitrobenzoylamide homo sapiens 141.0 141.0 1 PMID:18320560 -3.4.21.59 ac-ile-arg-asn-lys-5-amino-2-nitrobenzoylamide homo sapiens 367.0 367.0 1 PMID:18320560 -3.4.21.59 ac-pank-aac homo sapiens 3.5 2.3 2 PMID:11438529 -3.4.21.59 ac-prnk-aac homo sapiens 0.99 0.98 2 PMID:11438529 -3.4.21.59 ac-prnr-aac homo sapiens 21.8 21.75 3 PMID:11438529 -3.4.21.59 ac-pro-ile-arg-asn-lys-5-amino-2-nitrobenzoylamide homo sapiens 378.0 378.0 1 PMID:18320560 -3.4.21.59 ac-prtk-aac homo sapiens 1.1 1.045 2 PMID:11438529 -3.4.21.59 ala-ala-pro-ile-arg-asn-lys-5-amino-2-nitrobenzoylamide homo sapiens 187.0 187.0 1 PMID:18320560 -3.4.21.59 ala-pro-ile-arg-asn-lys-5-amino-2-nitrobenzoylamide homo sapiens 233.0 233.0 1 PMID:18320560 -3.4.21.59 arg-asn-lys-5-amino-2-nitrobenzoylamide homo sapiens 159.0 159.0 1 PMID:18320560 -3.4.21.59 benzyloxycarbonyl-ala-arg-arg 4-methylcoumarin 7-amide bos taurus 0.8 0.8 1 PMID:1515079 -3.4.21.59 benzyloxycarbonyl-arg 4-methylcoumarin 7-amide bos taurus 0.05 0.05 1 PMID:1515079 -3.4.21.59 benzyloxycarbonyl-arg 4-nitroanilide homo sapiens 5.52 5.435 2 PMID:3140898 -3.4.21.59 benzyloxycarbonyl-gly-arg 4-trifluoromethylcoumarin 7-amide homo sapiens 107.0 105.5 2 PMID:3140898 -3.4.21.59 benzyloxycarbonyl-gly-pro-arg 4-nitroanilide homo sapiens 553.0 552.0 2 PMID:3140898 -3.4.21.59 benzyloxycarbonyl-l-ala-l-arg-l-arg 4-methylcoumarin 7-amide homo sapiens 2040.0 2040.0 1 PMID:3543004 -3.4.21.59 benzyloxycarbonyl-l-ala-l-leu-l-lys-7-amido-4-methylcoumarin homo sapiens 1870.0 1870.0 1 PMID:3543004 -3.4.21.59 benzyloxycarbonyl-l-ala-l-lys-l-arg 4-methylcoumarin 7-amide homo sapiens 3290.0 3290.0 1 PMID:3543004 -3.4.21.59 benzyloxycarbonyl-l-ala-l-lys-l-lys 4-methylcoumarin 7-amide homo sapiens 1520.0 1520.0 1 PMID:3543004 -3.4.21.59 benzyloxycarbonyl-lys-arg 4-trifluoromethylcoumarin 7-amide homo sapiens 45.7 45.7 1 PMID:3140898 -3.4.21.59 bovine prothrombin rattus norvegicus 46.3 46.3 1 PMID:3904753 -3.4.21.59 bz-arg-p-nitroanilide homo sapiens 8.9 2.94 7 PMID:12605678 -3.4.21.59 d-ile-pro-arg-4-nitroanilide homo sapiens 170.0 133.5 2 PMID:17655281 -3.4.21.59 d-ile-pro-arg-p-nitroanilide homo sapiens 40.0 14.0 9 PMID:11401583 -3.4.21.59 d-phe-pip-arg-p-nitroanilide homo sapiens 59.5 39.05 4 PMID:12605678 -3.4.21.59 d-pro-phe-arg-p-nitroanilide homo sapiens 5.3 5.1 4 PMID:12605678 -3.4.21.59 d-val-leu-arg-p-nitroanilide homo sapiens 31.0 16.3 5 PMID:12605678 -3.4.21.59 glu-gly-arg-p-nitroanilide homo sapiens 183.0 60.6 3 PMID:12605678 -3.4.21.59 glu-pro-arg-p-nitroanilide homo sapiens 56.9 2.6 5 PMID:12605678 -3.4.21.59 ile-arg-asn-lys-5-amino-2-nitrobenzoylamide homo sapiens 199.0 199.0 1 PMID:18320560 -3.4.21.59 meoco-nle-gly-arg-p-nitroanilide homo sapiens 2630.0 30.5 5 PMID:12605678 -3.4.21.59 n-(p-tosyl)-gly-pro-arg-4-nitroanilide equus caballus 23.5 23.5 1 PMID:17014440 -3.4.21.59 n-(p-tosyl)-gly-pro-lys-p-nitroanilide equus caballus 12.0 12.0 1 PMID:17014440 -3.4.21.59 n-p-tosyl-gly-pro-arg-p-nitroanilide homo sapiens 21.0 21.0 1 PMID:10391906 -3.4.21.59 n-p-tosyl-gly-pro-lys-p-nitroanilide homo sapiens 540.0 515.0 2 PMID:10092484 -3.4.21.59 n-p-tosyl-gly-pro-lys-p-nitroanilide mus musculus 6.08 3.9 9 PMID:11401583 -3.4.21.59 pro-ile-arg-asn-lys-5-amino-2-nitrobenzoylamide homo sapiens 435.0 435.0 1 PMID:18320560 -3.4.21.59 s-2288 homo sapiens 87.0 87.0 1 PMID:29661938 -3.4.21.59 t-butyloxycarbonyl-phe-ser-arg-4-methyl-coumarin 7-amide bos taurus 7.0 7.0 1 PMID:11154069 -3.4.21.59 tert-butyloxycarbonyl-gly-lys-arg 4-methylcoumarin 7-amide bos taurus 0.5 0.5 1 PMID:1515079 -3.4.21.59 tert-butyloxycarbonyl-l-val-l-pro-l-arg-4-methylcoumarin 7-amide bos taurus 1.4 1.4 1 PMID:1515079 -3.4.21.59 tert-butyloxycarbonyl-phe-ser-arg 4-methylcoumarin 7-amide bos taurus 2.2 2.2 1 PMID:1515079 -3.4.21.59 tosyl-gly-pro-lys-p-nitroanilide homo sapiens 75.5 42.95 4 PMID:12605678 -3.4.21.59 z-d-arg-gly-arg-p-nitroanilide homo sapiens 10.3 4.2 4 PMID:12605678 -3.4.21.6 arg-gly-arg-4-nitroanilide homo sapiens 125.3 125.3 1 PMID:18457426 -3.4.21.6 benzoyl-ile-glu(piperidineamide)-gly-arg-p-nitroanilide bos taurus 149.0 147.0 2 PMID:3512564;PMID:7354070 -3.4.21.6 benzoyl-ile-glu-(-h/ome)-gly-arg-p-nitroanilide bos taurus 146.0 143.0 2 PMID:3512564;PMID:7354070 -3.4.21.6 fragment 1.2:prethrombin-2 homo sapiens 114.0 57.00285 2 PMID:12496269 -3.4.21.6 meizothrombin homo sapiens 150.0 78.195 2 PMID:12496269 -3.4.21.6 methoxycarbonylcyclohexyl-gly-gly-l-arg-4-nitroanilide homo sapiens 210.0 140.0 4 PMID:18460471 -3.4.21.6 n-alpha-benzyloxycarbonyl-d-arginyl-glycyl-l-arginine-4-nitroanilide homo sapiens 169.0 127.0 5 PMID:12022882;PMID:14596625 -3.4.21.6 nalpha-benzyloxycarbonyl-l-lys-p-nitrophenyl ester bos taurus 2.17 2.17 1 PMID:7354070 -3.4.21.6 prethrombin-1 homo sapiens 18.1 17.8 2 PMID:18460471 -3.4.21.6 prethrombin-2 homo sapiens 20.5 20.5 1 PMID:11687304 -3.4.21.6 prothrombin homo sapiens 108.0 21.3 14 PMID:11687304;PMID:12022882;PMID:12496269;PMID:14583605;PMID:18460471;PMID:19186135;PMID:19858193;PMID:21531712 -3.4.21.6 recombinant prothrombin r155a/r284a/r271a mutant rmz-ii homo sapiens 110.0 55.0034 2 PMID:12496269 -3.4.21.6 recombinant prothrombin r155a/r284a/r320a mutant rp2-ii homo sapiens 114.0 57.162 2 PMID:12496269 -3.4.21.6 s-2765 homo sapiens 21.0 21.0 1 PMID:28904343 -3.4.21.6 s2222 homo sapiens 211.0 211.0 1 PMID:14583605 -3.4.21.6 s2765 homo sapiens 254.0 254.0 1 PMID:14583605 -3.4.21.6 tosyl-glycyl-prolyl-d-arginine-4-nitroanilide homo sapiens 79.0 62.5 2 PMID:14596625 -3.4.21.60 prothrombin bothrops cotiara 0.00027 0.00021 2 PMID:16647309 -3.4.21.60 prothrombin oxyuranus scutellatus 1200.0 1200.0 1 PMID:14769787 -3.4.21.61 ac-aykk 4-methylcoumarin 7-amide saccharomyces cerevisiae 21.6 21.6 1 PMID:9521659 -3.4.21.61 ac-nle-tyr-lys-arg 4-methylcoumarin 7-amide saccharomyces cerevisiae 2700.0 2700.0 1 PMID:11297433 -3.4.21.61 ac-nle-ykk 4-methylcoumarin 7-amide saccharomyces cerevisiae 300.0 300.0 1 PMID:9521659 -3.4.21.61 ac-nle-ykr 4-methylcoumarin 7-amide saccharomyces cerevisiae 3000.0 3000.0 1 PMID:9521659 -3.4.21.61 benzyloxycarbonyl-ala-tyr-lys-lys 4-methylcoumarin 7-amide saccharomyces cerevisiae 2640.0 2640.0 1 PMID:10790301 -3.4.21.61 d-ac-nle-tyr-lys-arg 4-methylcoumarin 7-amide saccharomyces cerevisiae 2940.0 2940.0 1 PMID:11297433 -3.4.21.61 t-butyloxycarbonyl-ekk 4-methylcoumarin 7-amide saccharomyces cerevisiae 11.4 11.4 1 PMID:9521659 -3.4.21.61 t-butyloxycarbonyl-qgr 4-methylcoumarin 7-amide saccharomyces cerevisiae 366.0 366.0 1 PMID:9521659 -3.4.21.62 acetyl-l-phe bacillus subtilis 0.022 0.022 1 PMID:15649780 -3.4.21.62 acetyl-l-phe ethyl ester bacillus subtilis 0.38 0.38 1 PMID:15649780 -3.4.21.62 acetyl-l-tyr bacillus subtilis 0.1 0.1 1 PMID:15649780 -3.4.21.62 acetyl-l-tyr ethyl ester bacillus subtilis 0.04 0.04 1 PMID:15649780 -3.4.21.62 azocasein melghiribacillus thermohalophilus 0.736 0.736 1 PMID:31236718 -3.4.21.62 benzyloxycarbonyl-gly-4-nitroanilide bacillus sp. (in: firmicutes) 2500.0 2200.0 2 PMID:10926860 -3.4.21.62 benzyloxycarbonyl-l-ala-l-ala-l-leu-4-nitroanilide bacillus intermedius 16550.0 16550.0 1 PMID:15170378 -3.4.21.62 casein bacillus subtilis 483.9 483.9 1 PMID:37517759 -3.4.21.62 casein melghiribacillus thermohalophilus 1.053 1.053 1 PMID:31236718 -3.4.21.62 casein shewanella frigidimarina 5.186 5.186 1 * -3.4.21.62 glp-ala-ala-leu-p-nitroanilide bacillus licheniformis 69.0 69.0 1 * -3.4.21.62 glp-ala-ala-leu-p-nitroanilide bacillus subtilis 80.0 72.15 2 * -3.4.21.62 hammarsten casein shouchella clausii 35.5 35.5 1 PMID:15988584 -3.4.21.62 l-ala-l-ala-l-pro-l-ala lederbergia lenta 47.0 39.0 2 PMID:15047911 -3.4.21.62 l-ala-l-ala-l-pro-l-phe lederbergia lenta 403.0 294.0 2 PMID:15047911 -3.4.21.62 l-ala-l-ala-l-val-l-ala lederbergia lenta 12.0 11.0 2 PMID:15047911 -3.4.21.62 l-phe-l-ala-l-ala-l-phe lederbergia lenta 189.0 139.5 2 PMID:15047911 -3.4.21.62 l-tyr-l-val-l-ala-l-asp lederbergia lenta 10.0 7.0 2 PMID:15047911 -3.4.21.62 meo-succinyl-ala-ala-phe 4-nitroanilide bacillus amyloliquefaciens 57.0 57.0 1 * -3.4.21.62 meo-succinyl-ala-ala-phe 4-nitroanilide bacillus sp. (in: firmicutes) 97.0 57.0 3 * -3.4.21.62 n-benzoyl-l-tyrosine ethyl ester melghiribacillus thermohalophilus 0.436 0.436 1 PMID:31236718 -3.4.21.62 n-methoxysuccinyl-ala-ala-pro-val-4-nitroanilide dichelobacter nodosus 0.0089 0.0076500000000000005 2 PMID:21990366 -3.4.21.62 n-succ-ala-ala-pro-phe-4-nitroanilide bacillus amyloliquefaciens 231.3 231.3 1 PMID:21780825 -3.4.21.62 n-succinyl-ala-ala-pro-phe-4-nitroanilide bacillus licheniformis 419.0 295.8 2 PMID:22326746;PMID:23835157 -3.4.21.62 n-succinyl-ala-ala-pro-phe-4-nitroanilide bacillus subtilis 552.3 225.7 5 PMID:30502512 -3.4.21.62 n-succinyl-ala-ala-pro-phe-p-nitroanilide thermococcus kodakarensis 440.0 19.5 4 PMID:20100702 -3.4.21.62 n-succinyl-l-ala-l-ala-l-pro-l-phe-4-nitroanilide shouchella clausii 70.2 70.2 1 PMID:15988584 -3.4.21.62 n-succinyl-l-phe-l-ala-l-ala-l-phe-4-nitroanilide bacillus subtilis 309.3 309.3 1 PMID:37517759 -3.4.21.62 n-succinyl-l-phe-l-ala-l-ala-l-phe-4-nitroanilide melghiribacillus thermohalophilus 1.947 1.947 1 PMID:31236718 -3.4.21.62 suc-ala-ala-ala-p-nitroanilide bacillus sp. (in: firmicutes) 97000.0 1200.0 5 PMID:10926860 -3.4.21.62 suc-ala-ala-p-nitroanilide bacillus sp. (in: firmicutes) 3700.0 1896.5 2 PMID:10926860 -3.4.21.62 suc-ala-ala-pro-ala-p-nitroanilide bacillus sp. (in: firmicutes) 130000.0 8800.0 3 PMID:10926860 -3.4.21.62 suc-ala-ala-pro-leu-p-nitroanilide bacillus sp. (in: firmicutes) 97000.0 48694.5 2 PMID:10926860 -3.4.21.62 suc-ala-ala-pro-phe-4-nitroanilide fusarium equiseti 137.0 137.0 1 PMID:26178876 -3.4.21.62 suc-ala-ala-pro-phe-4-nitroanilide synthetic construct 200.0 149.0 4 PMID:19132746 -3.4.21.62 succinyl-aapa-p-nitroanilide lederbergia lenta 17.7 17.7 1 PMID:10529215 -3.4.21.62 succinyl-aape-p-nitroanilide lederbergia lenta 1.75 1.75 1 PMID:10529215 -3.4.21.62 succinyl-aapf-p-nitroanilide lederbergia lenta 153.0 100.5 2 PMID:10529215;PMID:9558332 -3.4.21.62 succinyl-aapr-p-nitroanilide lederbergia lenta 0.16 0.16 1 PMID:10529215 -3.4.21.62 succinyl-ala-ala-ala 4-nitroanilide bacillus sp. (in: firmicutes) 1.8 1.7000000000000002 2 * -3.4.21.62 succinyl-ala-ala-phe-4-nitroanilide bacillus sp. (in: firmicutes) 52.0 52.0 1 * -3.4.21.62 succinyl-ala-ala-pro-phe 4-nitroanilide bacillus amyloliquefaciens 57.0 57.0 1 * -3.4.21.62 succinyl-ala-ala-pro-phe 4-nitroanilide bacillus sp. (in: firmicutes) 57.0 57.0 1 * -3.4.21.62 succinyl-ala-ala-pro-phe-4-nitroanilide bacillus sp. (in: firmicutes) 130000.0 6450.0 4 PMID:10926860 -3.4.21.62 succinyl-l-ala-l-ala-l-pro-l-phe-4-methyl-coumaryl-7-amide bacillus subtilis 50.0 35.0 3 PMID:22408062 -3.4.21.62 succinyl-leu-leu-val-tyr-4-methylcoumaryl 7-amide bacillus sp. (in: firmicutes) 29.0 29.0 1 PMID:7605625 -3.4.21.62 urea-denatured hemoglobin bacillus subtilis 0.04 0.04 1 PMID:15649780 -3.4.21.62 z-ala-ala-leu-p-nitroanilide bacillus licheniformis 104.0 90.5 2 * -3.4.21.62 z-ala-ala-leu-p-nitroanilide bacillus subtilis 100.0 85.45 2 * -3.4.21.63 acetyl-(ala)2 methyl ester aspergillus melleus 2000.0 2000.0 1 PMID:4441086 -3.4.21.63 acetyl-(ala)2 methyl ester aspergillus sojae 1150.0 1150.0 1 PMID:4441086 -3.4.21.63 acetyl-(ala)3 methyl ester aspergillus melleus 1540.0 1540.0 1 PMID:4441086 -3.4.21.63 acetyl-(ala)3 methyl ester aspergillus oryzae 2850.0 2850.0 1 PMID:4736151 -3.4.21.63 acetyl-(ala)3 methyl ester aspergillus sojae 3720.0 3720.0 1 PMID:4441086 -3.4.21.63 acetyl-(ala)4 methyl ester aspergillus melleus 1970.0 1970.0 1 PMID:4441086 -3.4.21.63 acetyl-(ala)4 methyl ester aspergillus sojae 2090.0 2090.0 1 PMID:4441086 -3.4.21.63 acetyl-ala methyl ester aspergillus melleus 28.3 28.3 1 PMID:4441086 -3.4.21.63 acetyl-ala methyl ester aspergillus sojae 28.9 28.9 1 PMID:4441086 -3.4.21.63 acetyl-l-tyrosine ethyl ester aspergillus oryzae 43.0 43.0 1 PMID:4736151 -3.4.21.63 azocasein aspergillus heteromorphus 3.7 3.7 1 PMID:38885866 -3.4.21.63 benzoylarginine ethyl ester aspergillus oryzae 41.0 41.0 1 PMID:4736151 -3.4.21.63 casein bacillus licheniformis 1.392 1.392 1 PMID:26634394 -3.4.21.64 casein parengyodontium album 3364.0 3364.0 1 PMID:31706815 -3.4.21.64 succinyl-aapf-4-nitroanilide parengyodontium album 180.0 88.0 3 PMID:16367747 -3.4.21.64 succinyl-aapf-4-nitroanilide serratia sp. (in: enterobacteria) 827.0 364.0 3 PMID:16367747 -3.4.21.65 acetyl-ala-ala-ala methyl ester malbranchea pulchella 2050.0 2050.0 1 PMID:3173 -3.4.21.66 n-succinyl-ala-ala-pro-phe-4-nitroanilide coprothermobacter proteolyticus 110.0 37.0 3 PMID:23851086 -3.4.21.68 (p-f)-fpransnh-c2h5 homo sapiens 6.08 1.47 5 PMID:9047311 -3.4.21.68 [snase]-pfgrsa homo sapiens 0.0041 0.0041 1 PMID:9468480 -3.4.21.68 [snase]-pfgrsag homo sapiens 0.018 0.018 1 PMID:9468480 -3.4.21.68 [snase]-pgpfgrsag homo sapiens 0.0075 0.0075 1 PMID:9468480 -3.4.21.68 [snase]-pgpfgrsagg homo sapiens 0.01 0.01 1 PMID:9468480 -3.4.21.68 [snase]-phygrsgg homo sapiens 0.012 0.012 1 PMID:9468480 -3.4.21.68 [snase]-ppfgrsag homo sapiens 0.011 0.011 1 PMID:9468480 -3.4.21.68 [snase]-pqrgrsag homo sapiens 0.006 0.006 1 PMID:9468480 -3.4.21.68 acetyl-ftar-4-nitroanilide homo sapiens 0.24 0.24 1 PMID:30225958 -3.4.21.68 acetyl-fyar-4-nitroanilide homo sapiens 0.86 0.86 1 PMID:30225958 -3.4.21.68 acetyl-gtar-4-nitroanilide homo sapiens 0.36 0.36 1 PMID:30225958 -3.4.21.68 acetyl-gtgr-4-nitroanilide homo sapiens 0.21 0.21 1 PMID:30225958 -3.4.21.68 acetyl-qyar-4-nitroanilide homo sapiens 0.46 0.46 1 PMID:30225958 -3.4.21.68 boc-(p-f)-fpransnh-c2h5 homo sapiens 6.08 1.03 5 PMID:9047311 -3.4.21.68 boc-d-flransnh-c3h7 homo sapiens 4.7 0.047 5 PMID:9047311 -3.4.21.68 boc-d-fpransnh-c6h11 homo sapiens 0.15 0.08349999999999999 2 PMID:9047311 -3.4.21.68 boc-d-fvr-ansnh-c2h5 homo sapiens 7.9 7.9 1 PMID:9047311 -3.4.21.68 boc-d-fvransnh-c2h5 homo sapiens 0.49 0.097 4 PMID:9047311 -3.4.21.68 boc-d-lgransnh-c6h11 homo sapiens 3.3 0.0685 4 PMID:9047311 -3.4.21.68 boc-d-lpransnh-c3h7 homo sapiens 6.08 0.54 5 PMID:9047311 -3.4.21.68 boc-d-lsransnh-c3h7 homo sapiens 6.08 0.53 5 PMID:9047311 -3.4.21.68 boc-d-vgransnh-c4h9 homo sapiens 5.0 0.18 5 PMID:9047311 -3.4.21.68 boc-d-vpransnh-c4h9 homo sapiens 3.8 0.25 4 PMID:9047311 -3.4.21.68 boc-l-vgransnhc4h9 homo sapiens 0.084 0.084 1 PMID:9047311 -3.4.21.68 d-flransnh-c3h7 homo sapiens 0.018 0.018 1 PMID:9047311 -3.4.21.68 d-fpr-ansnh-c6h11 homo sapiens 0.016 0.016 1 PMID:9047311 -3.4.21.68 d-fpr-ansnh-c6h5ch2 homo sapiens 0.45 0.45 1 PMID:9047311 -3.4.21.68 d-fpr-ansnh-n-c4h9 homo sapiens 0.47 0.47 1 PMID:9047311 -3.4.21.68 d-fpr-ansnh-n-c6h13 homo sapiens 3.6 3.45 2 PMID:9047311 -3.4.21.68 d-fpr-ansnh-t-c4h9 homo sapiens 3.8 3.8 1 PMID:9047311 -3.4.21.68 d-fpr-ansnhc6h11 homo sapiens 6.08 3.295 2 PMID:9047311 -3.4.21.68 d-fpransn-(ch2)6 homo sapiens 1.7 0.22 3 PMID:9047311 -3.4.21.68 d-fpransn-c2h5-c2h5 homo sapiens 1.6 0.14 3 PMID:9047311 -3.4.21.68 d-fpransn-h-c-c6h11 homo sapiens 0.15 0.15 1 PMID:9047311 -3.4.21.68 d-fpransn-h-i-c3h7 homo sapiens 0.2 0.2 1 PMID:9047311 -3.4.21.68 d-fpransn-h-t-c4h9 homo sapiens 6.08 0.94 3 PMID:9047311 -3.4.21.68 d-fpransnh-c-c6h11 homo sapiens 2.1 1.21 2 PMID:9047311 -3.4.21.68 d-fpransnh-c2h4och3 homo sapiens 6.08 1.53 4 PMID:9047311 -3.4.21.68 d-fpransnh-c6h11 homo sapiens 32.0 32.0 1 PMID:9047311 -3.4.21.68 d-fpransnh-c6h5ch2 homo sapiens 6.08 1.2 3 PMID:9047311 -3.4.21.68 d-fpransnh-ch2cooch3 homo sapiens 1.8 0.15 3 PMID:9047311 -3.4.21.68 d-fpransnh-i-c3h7 homo sapiens 6.08 0.69 3 PMID:9047311 -3.4.21.68 d-fpransnh-n-c4h9 homo sapiens 1.4 0.865 2 PMID:9047311 -3.4.21.68 d-fpransnh-n-c6h13 homo sapiens 1.1 1.1 1 PMID:9047311 -3.4.21.68 d-fvr-ansnh-c2h5 homo sapiens 0.025 0.025 1 PMID:9047311 -3.4.21.68 d-fvransnh-c2h5 homo sapiens 2.3 1.1555 2 PMID:9047311 -3.4.21.68 d-ile-pro-arg-p-nitroanilide homo sapiens 10.7 0.06004999999999999 8 PMID:17408411 -3.4.21.68 d-lgr-ansnh-c6h11 homo sapiens 4.0 2.017 2 PMID:9047311 -3.4.21.68 d-lgransnh-c6h11 homo sapiens 0.057 0.0327 2 PMID:9047311 -3.4.21.68 d-lpransnh-c3h7 homo sapiens 2.8 0.24 4 PMID:9047311 -3.4.21.68 d-lsransnh-c3h7 homo sapiens 5.3 0.1 3 PMID:9047311 -3.4.21.68 d-lsransnhc3h7 homo sapiens 89.0 89.0 1 PMID:9047311 -3.4.21.68 d-vgransnh-c4h9 homo sapiens 9.0 0.19 3 PMID:9047311 -3.4.21.68 d-vpransnh-c4h9 homo sapiens 2.7 0.71 5 PMID:9047311 -3.4.21.68 l-fpransnh-c2h5 homo sapiens 0.04 0.04 1 PMID:9047311 -3.4.21.68 l-vgransnh-c4h9 homo sapiens 0.08 0.08 1 PMID:9047311 -3.4.21.68 lys-lys-cys-pro-gly-arg-val-val-gly-gly-cys-val-ala-his homo sapiens 0.009 0.009 1 PMID:7706303 -3.4.21.68 lys-lys-ser-pro-gly-arg-val-val-gly-gly-ser-val-ala-his homo sapiens 0.0012 0.0012 1 PMID:7706303 -3.4.21.68 lys-plasminogen homo sapiens 0.1 0.084 2 PMID:8999865 -3.4.21.68 plasminogen bos taurus 0.0025 0.0025 1 PMID:9730836 -3.4.21.68 plasminogen homo sapiens 0.4718 0.2 5 PMID:10212215;PMID:19180513;PMID:7706303 -3.4.21.69 benzyloxycarbonyl-val-gly-arg homo sapiens 0.38 0.38 1 PMID:3863616 -3.4.21.69 d-ile-pro-arg homo sapiens 200.0 200.0 1 PMID:3863616 -3.4.21.69 d-phe-pipecolyl-arg homo sapiens 53.0 53.0 1 PMID:3863616 -3.4.21.69 d-pro-phe-arg homo sapiens 31.0 31.0 1 PMID:3863616 -3.4.21.69 d-val-cyclohexyl-ala-arg homo sapiens 1.9 1.9 1 PMID:3863616 -3.4.21.69 d-val-leu-arg homo sapiens 35.0 35.0 1 PMID:3863616 -3.4.21.69 factor va homo sapiens 0.395 0.395 1 PMID:20390226 -3.4.21.69 factor var506q homo sapiens 0.37 0.37 1 PMID:7673148 -3.4.21.69 membrane-bound factor va homo sapiens 0.96 0.96 1 PMID:7673148 -3.4.21.69 nalpha-benzoyl-l-arginine 4-nitroanilide bos taurus 0.32 0.32 1 PMID:2986681 -3.4.21.69 s-2366 homo sapiens 70.0 70.0 1 PMID:11316800 -3.4.21.69 spectrozyme pca homo sapiens 44.0 44.0 1 PMID:11994010 -3.4.21.69 sppca homo sapiens 33.1 33.1 1 PMID:17580306 -3.4.21.69 toluene-p-sulfonyl-gly-pro-arg homo sapiens 87.0 87.0 1 PMID:3863616 -3.4.21.69 toluene-p-sulfonyl-gly-pro-lys homo sapiens 0.81 0.81 1 PMID:3863616 -3.4.21.7 4-nitrophenyl-p'-(guanidinium)benzoate bromide oryctolagus cuniculus 0.125 0.125 1 PMID:132894 -3.4.21.7 aiyrsr homo sapiens 0.036 0.036 1 PMID:10873836 -3.4.21.7 benzyloxycarbonyl-lys-p-nitrophenyl ester homo sapiens 22.3 12.200000000000001 2 PMID:6210828 -3.4.21.7 ciyrsr homo sapiens 2.7 2.7 1 PMID:10873836 -3.4.21.7 d-val-l-leu-l-lys-4-nitroanilide homo sapiens 12.97 12.8 3 PMID:18766256;PMID:25576865 -3.4.21.7 d-val-leu-lys-p-nitroanilide homo sapiens 25.7 25.5 3 PMID:6210828 -3.4.21.7 givrsr homo sapiens 0.039 0.039 1 PMID:10873836 -3.4.21.7 giyrsr homo sapiens 1.5 1.05 2 PMID:10873836 -3.4.21.7 gpgrvv homo sapiens 0.0016 0.0016 1 PMID:10873836 -3.4.21.7 hemofiltrate cc chemokine 1 homo sapiens 6.0 6.0 1 PMID:11544332 -3.4.21.7 kkspgrvvggsvah homo sapiens 0.0086 0.0086 1 PMID:10873836 -3.4.21.7 lggsamsrmssle homo sapiens 3.2 3.2 1 PMID:10873836 -3.4.21.7 lggsganfrgkle homo sapiens 68.0 68.0 1 PMID:10873836 -3.4.21.7 lggsgavykagle homo sapiens 40.0 40.0 1 PMID:10873836 -3.4.21.7 lggsgigrsrsle homo sapiens 53.0 53.0 1 PMID:10873836 -3.4.21.7 lggsgiyrsrsle homo sapiens 120.0 120.0 1 PMID:10873836 -3.4.21.7 lggsgiyrsvsle homo sapiens 39.0 39.0 1 PMID:10873836 -3.4.21.7 lggsgiyrvrsle homo sapiens 16.0 16.0 1 PMID:10873836 -3.4.21.7 lggsgpyrsrsle homo sapiens 92.0 92.0 1 PMID:10873836 -3.4.21.7 lggsgtqrrlrle homo sapiens 12.0 12.0 1 PMID:10873836 -3.4.21.7 lggsgykiggsle homo sapiens 12.0 12.0 1 PMID:10873836 -3.4.21.7 lggsirykgksle homo sapiens 44.0 44.0 1 PMID:10873836 -3.4.21.7 lggssiyrsrsle homo sapiens 35.0 35.0 1 PMID:10873836 -3.4.21.7 p-nitrophenyl-p'-(methylethylsulfoniummethyl)benzoate oryctolagus cuniculus 0.144 0.1305 2 PMID:132894 -3.4.21.7 p-nitrophenyl-p'-(pyridiniummethyl)-benzoate oryctolagus cuniculus 0.127 0.1245 2 PMID:132894 -3.4.21.7 p-nitrophenyl-p'-(thiouroniummethyl)benzoate oryctolagus cuniculus 0.364 0.34850000000000003 2 PMID:132894 -3.4.21.7 spgrvv homo sapiens 0.039 0.039 1 PMID:10873836 -3.4.21.7 thrombin-activatable fibrinolysis inhibitor homo sapiens 0.00042 0.00042 1 PMID:19335449 -3.4.21.70 acetyl-tri-l-alanine methyl ester sus scrofa 59.0 59.0 1 PMID:7007383 -3.4.21.70 benzoyl-l-alanine methyl ester sus scrofa 6.3 6.3 1 PMID:7007383 -3.4.21.70 succinyl-tri-l-alanine 4-nitroanilide sus scrofa 7.5 7.5 1 PMID:7007383 -3.4.21.71 gly-ile-asp-val-gln-ile-tyr bos taurus 2.1 2.1 1 PMID:11838546 -3.4.21.73 l-diglutamyl-glycyl-l-arginine-4-nitroanilide homo sapiens 0.0113 0.009399999999999999 2 PMID:1540190 -3.4.21.73 plasminogen homo sapiens 14.1 12.4 3 PMID:1527056;PMID:1540190 -3.4.21.73 pyroglu-gly-arg-4-nitroanilide homo sapiens 773.0 386.865 2 PMID:19705874 -3.4.21.73 s2444 homo sapiens 0.32 0.32 1 PMID:9295329 -3.4.21.74 benzoyl-pro-phe-arg 4-nitroanilide crotalus adamanteus 0.35 0.35 1 PMID:2934864 -3.4.21.74 carbobenzoxyl-glu-(alpha-tert-butoxy)-gly-arg-4-nitroanilide crotalus adamanteus 0.16 0.16 1 PMID:2934864 -3.4.21.74 d-phenylglycyl-phe-arg 4-nitroanilide crotalus adamanteus 3.5 3.5 1 PMID:2934864 -3.4.21.74 h-d-aminobutyric acid-cyclohexylalanyl-lys 4-nitroanilide crotalus adamanteus 1.4 1.4 1 PMID:2934864 -3.4.21.74 h-d-cyclohexylglycyl-l-2-aminobutyryl-arg 4-nitroanilide crotalus adamanteus 0.68 0.68 1 PMID:2934864 -3.4.21.74 h-d-hexahydrotyrosyl-ala-arg 4-nitroanilide crotalus adamanteus 0.95 0.95 1 PMID:2934864 -3.4.21.74 h-d-nle-cyclohexylalanyl-arg 4-nitroanilide crotalus adamanteus 61.0 61.0 1 PMID:2934864 -3.4.21.74 h-d-nle-hexahydrotyrosyl-lys 4-nitroanilide crotalus adamanteus 6.9 6.9 1 PMID:2934864 -3.4.21.74 h-d-pro-hexahydrotyrosyl-arg 4-nitroanilide crotalus adamanteus 4.9 4.9 1 PMID:2934864 -3.4.21.74 human plasma fibrinogen daboia russelii russelii 1.042 0.335 4 PMID:24520323 -3.4.21.74 methylsulfonyl-leu-gly-arg 4-nitroanilide crotalus adamanteus 1.3 1.3 1 PMID:2934864 -3.4.21.74 tosyl-gly-pro-arg 4-nitroanilide crotalus adamanteus 11.5 11.5 1 PMID:2934864 -3.4.21.74 tosyl-gly-pro-lys 4-nitroanilide crotalus adamanteus 0.7 0.7 1 PMID:2934864 -3.4.21.75 2-aminobenzoyl-arg-val-lys-arg-gly-leu-ala-tyr(no2)-asp-oh mammalia 29.3 29.3 1 PMID:7710100 -3.4.21.75 abz-girrkrsvshq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 30.3 29.950000000000003 2 PMID:20635860 -3.4.21.75 abz-grrtrreaivq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 4.2 3.9000000000000004 2 PMID:20635860 -3.4.21.75 abz-hhrqrrsvsiq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 39.5 34.2 2 PMID:20635860 -3.4.21.75 abz-hkrekrqakhq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 6.9 6.6 2 PMID:20635860 -3.4.21.75 abz-hrrekrsvalq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 12.2 9.899999999999999 2 PMID:20635860 -3.4.21.75 abz-hrrqkrsvalq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 14.9 12.05 2 PMID:20635860 -3.4.21.75 abz-kirrrrdvvdq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.1 1.85 2 PMID:20635860 -3.4.21.75 abz-lkrrrrdtqqq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 6.7 3.6550000000000002 2 PMID:20635860 -3.4.21.75 abz-nlrrrrdlvdq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.5 2.75 2 PMID:20635860 -3.4.21.75 abz-rerrrkkrglfgq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 12.3 7.45 2 PMID:20635860 -3.4.21.75 abz-rkrsrrqvntq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 11.3 9.850000000000001 2 PMID:20635860 -3.4.21.75 abz-rrrakrspkhq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 8.7 7.0 2 PMID:20635860 -3.4.21.75 abz-rrrdkrsvalq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 14.6 13.399999999999999 2 PMID:20635860 -3.4.21.75 abz-rrrkkrglfgq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 5.0 5.0 1 PMID:20635860 -3.4.21.75 abz-rrrkkrglsgq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 6.7 4.55 2 PMID:20635860 -3.4.21.75 abz-rrrkkrslfgq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 7.6 4.3 2 PMID:20635860 -3.4.21.75 abz-skrsrrsvsvq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 18.3 14.4 2 PMID:20635860 -3.4.21.75 abz-srrhkrfagvq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.4 1.305 2 PMID:20635860 -3.4.21.75 abz-srrkrrdvtpq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 9.9 9.55 2 PMID:20635860 -3.4.21.75 abz-srrkrrsastq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 11.1 10.55 2 PMID:20635860 -3.4.21.75 abz-ssrhrraldtq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 7.1 6.35 2 PMID:20635860 -3.4.21.75 abz-trrfrrsiteq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 19.8 18.1 2 PMID:20635860 -3.4.21.75 ac-arg-arg-arg-tle-lys-arg-7-amido-4-methylcoumarin homo sapiens 0.45 0.45 1 PMID:35964735 -3.4.21.75 ac-arg-arg-arg-tle-lys-arg-amc homo sapiens 0.45 0.45 1 PMID:35964735 -3.4.21.75 ac-arg-arg-tle-arg-arg-7-amido-4-methylcoumarin homo sapiens 1.18 1.18 1 PMID:35964735 -3.4.21.75 ac-arg-arg-tle-arg-arg-amc homo sapiens 1.18 1.18 1 PMID:35964735 -3.4.21.75 ac-arg-arg-tle-lys-arg-7-amido-4-methylcoumarin homo sapiens 0.373 0.373 1 PMID:35964735 -3.4.21.75 ac-arg-arg-tle-lys-arg-amc homo sapiens 0.373 0.373 1 PMID:35964735 -3.4.21.75 ac-arg-arg-tyr-lys-arg-7-amido-4-methylcoumarin homo sapiens 0.843 0.843 1 PMID:35964735 -3.4.21.75 ac-arg-arg-tyr-lys-arg-amc homo sapiens 0.843 0.843 1 PMID:35964735 -3.4.21.75 ac-arg-arg-val-lys-arg-7-amido-4-methylcoumarin homo sapiens 0.373 0.373 1 PMID:35964735 -3.4.21.75 ac-arg-arg-val-lys-arg-amc homo sapiens 0.373 0.373 1 PMID:35964735 -3.4.21.75 ac-arg-val-arg-arg-7-amido-4-methylcoumarin homo sapiens 0.584 0.584 1 PMID:35964735 -3.4.21.75 ac-arg-val-arg-arg-amc homo sapiens 0.584 0.584 1 PMID:35964735 -3.4.21.75 acetyl-arg-glu-lys-arg-4-methylcoumarin 7-amide homo sapiens 0.000934 0.000934 1 PMID:7642593 -3.4.21.75 acetyl-arg-lys-lys-arg-4-methylcoumarin 7-amide homo sapiens 0.02 0.02 1 PMID:7642593 -3.4.21.75 acetyl-arg-phe-ala-arg-4-methylcoumarin 7-amide homo sapiens 0.0507 0.0507 1 PMID:7642593 -3.4.21.75 acetyl-arg-pro-lys-arg-4-methylcoumarin 7-amide homo sapiens 0.00111 0.00111 1 PMID:7642593 -3.4.21.75 acetyl-arg-ser-lys-arg-4-methylcoumarin 7-amide homo sapiens 0.0403 0.0403 1 PMID:7642593 -3.4.21.75 acetyl-lys-ser-lys-arg-4-methylcoumarin 7-amide homo sapiens 0.00159 0.00159 1 PMID:7642593 -3.4.21.75 acetyl-norleucine-ykr-7-amido-4-methylcoumarin homo sapiens 50.0 50.0 1 PMID:10438496 -3.4.21.75 acetyl-orn-ser-lys-arg-4-methylcoumarin 7-amide homo sapiens 0.00088 0.00088 1 PMID:7642593 -3.4.21.75 acetyl-rvrr-4-methylcoumarin 7-amide homo sapiens 0.7 0.7 1 PMID:19477160 -3.4.21.75 acetyl-tyr-glu-lys-glu-arg-ser-lys-7-amido-4-methylcoumarin homo sapiens 0.00135 0.00135 1 PMID:7642593 -3.4.21.75 acrarykr-4-methylcoumarin-7-amide homo sapiens 250.0 250.0 1 PMID:10438496 -3.4.21.75 acrykr-4-methylcoumarin-7-amide homo sapiens 193.0 193.0 1 PMID:10438496 -3.4.21.75 acryrfkr-4-methylcoumarin-7-amide homo sapiens 200.0 200.0 1 PMID:10438496 -3.4.21.75 arg-arg-arg-tle-lys-arg-7-amido-4-methylcoumarin homo sapiens 0.339 0.339 1 PMID:35964735 -3.4.21.75 arg-arg-tle-lys-arg-7-amido-4-methylcoumarin homo sapiens 0.583 0.583 1 PMID:35964735 -3.4.21.75 boc-rvrr-4-methylcoumarin-7-amide homo sapiens 21.0 21.0 1 PMID:10438496 -3.4.21.75 boc-rvrr-7-amido-4-methylcoumarin trichoplusia ni 0.003 0.003 1 PMID:16472080 -3.4.21.75 h-arg-arg-arg-tle-lys-arg-amc homo sapiens 0.339 0.339 1 PMID:35964735 -3.4.21.75 h-arg-arg-tle-lys-arg-amc homo sapiens 0.583 0.583 1 PMID:35964735 -3.4.21.75 hbmp-2 precursor protein homo sapiens 3.6 3.3 2 PMID:19477160 -3.4.21.75 hbmp-4 precursor protein homo sapiens 5.6 4.6 2 PMID:19477160 -3.4.21.75 perktr-7-amido-4-methylcoumarin trichoplusia ni 0.008 0.008 1 PMID:16472080 -3.4.21.75 phac-arg-tle-arg-arg-7-amido-4-methylcoumarin homo sapiens 1.91 1.91 1 PMID:35964735 -3.4.21.75 phac-arg-tle-arg-arg-amc homo sapiens 1.91 1.91 1 PMID:35964735 -3.4.21.75 phac-arg-tle-lys-arg-7-amido-4-methylcoumarin homo sapiens 0.698 0.698 1 PMID:35964735 -3.4.21.75 phac-arg-tle-lys-arg-amc homo sapiens 0.698 0.698 1 PMID:35964735 -3.4.21.75 phac-arg-val-arg-arg-7-amido-4-methylcoumarin homo sapiens 0.585 0.585 1 PMID:35964735 -3.4.21.75 phac-arg-val-arg-arg-amc homo sapiens 0.585 0.585 1 PMID:35964735 -3.4.21.75 phac-arg-val-lys-arg-7-amido-4-methylcoumarin homo sapiens 0.597 0.597 1 PMID:35964735 -3.4.21.75 phac-arg-val-lys-arg-amc homo sapiens 0.597 0.597 1 PMID:35964735 -3.4.21.75 pro-hadam-15 protein homo sapiens 5.5 5.5 1 PMID:19477160 -3.4.21.75 pro-hadam-ts 4 protein homo sapiens 4.5 4.5 1 PMID:19477160 -3.4.21.75 pro-hadam-ts 6 protein homo sapiens 40.0 40.0 1 PMID:19477160 -3.4.21.75 pro-hadamts-17 protein homo sapiens 1.0 1.0 1 PMID:19477160 -3.4.21.75 pro-hadamts-23 protein homo sapiens 1.0 1.0 1 PMID:19477160 -3.4.21.75 pro-htgf-beta1 protein homo sapiens 1.5 1.5 1 PMID:19477160 -3.4.21.75 pro-htgf-beta2 protein homo sapiens 3.4 3.4 1 PMID:19477160 -3.4.21.75 pro-htgf-beta3 protein homo sapiens 8.4 8.4 1 PMID:19477160 -3.4.21.75 pro-htgf-beta4 protein homo sapiens 1.2 1.2 1 PMID:19477160 -3.4.21.75 pro-mt-mmp 1 protein homo sapiens 2.4 2.4 1 PMID:19477160 -3.4.21.75 pro-mt-mmp 11 protein homo sapiens 1.3 1.3 1 PMID:19477160 -3.4.21.75 pro-mt-mmp 3 protein homo sapiens 0.5 0.5 1 PMID:19477160 -3.4.21.75 pro-mt-mmp 4 protein homo sapiens 5.5 5.5 1 PMID:19477160 -3.4.21.75 pro-mt-mmp 6 protein homo sapiens 0.84 0.84 1 PMID:19477160 -3.4.21.75 proaerolysin homo sapiens 12.2 12.2 1 PMID:19477160 -3.4.21.75 protective antigen mammalia 11.0 11.0 1 PMID:7710100 -3.4.21.75 pseudomonas toxin homo sapiens 0.54 0.54 1 PMID:19477160 -3.4.21.75 pyr-arg-thr-lys-arg-7-amido-4-methylcoumarin homo sapiens 0.296 0.296 1 PMID:35964735 -3.4.21.75 pyr-arg-thr-lys-arg-amc homo sapiens 0.296 0.296 1 PMID:35964735 -3.4.21.75 shiga toxin homo sapiens 16.0 16.0 1 PMID:19477160 -3.4.21.75 tert-butoxycarbonyl-arg-val-arg-arg-4-methylcoumarin 7-amide mammalia 0.192 0.192 1 PMID:7710100 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzamide) homo sapiens 5.9 5.9 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-ala-nh2 homo sapiens 2.1 2.1 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-arg-nh2 homo sapiens 2.6 2.6 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-asn-nh2 homo sapiens 5.3 5.3 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-asp-nh2 homo sapiens 4.8 4.8 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-gln-nh2 homo sapiens 6.4 6.4 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-glu-nh2 homo sapiens 3.3 3.3 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-gly-nh2 homo sapiens 3.2 3.2 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-his-nh2 homo sapiens 3.1 3.1 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-ile-nh2 homo sapiens 1.8 1.8 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-leu-nh2 homo sapiens 2.0 2.0 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-lys-nh2 homo sapiens 2.5 2.5 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-phe-nh2 homo sapiens 1.3 1.3 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-pro-nh2 homo sapiens 1.1 1.1 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-ser-nh2 homo sapiens 5.1 5.1 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-thr-nh2 homo sapiens 2.8 2.8 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-trp-nh2 homo sapiens 1.3 1.3 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-tyr-nh2 homo sapiens 1.6 1.6 1 PMID:20074540 -3.4.21.76 abz-tyr-tyr-abu-(5-amino-2-nitrobenzoyl)-val-nh2 homo sapiens 4.7 4.7 1 PMID:20074540 -3.4.21.76 ac-ala-ala-pro-ala-p-nitroanilide homo sapiens 13.2 13.2 1 PMID:12538645 -3.4.21.76 ac-ala-ala-pro-val-p-nitroanilide homo sapiens 60.0 60.0 1 PMID:12538645 -3.4.21.76 boc-ala-ala-pro-ala-p-nitroanilide homo sapiens 18.0 18.0 1 PMID:12538645 -3.4.21.76 meosuc-aapv-4-nitroanilide homo sapiens 0.59 0.59 1 PMID:16182289 -3.4.21.76 meosuc-aapv-4-nitroanilide mus musculus 6.2 6.2 1 PMID:16182289 -3.4.21.76 meosuc-aipm-4-nitroanilide homo sapiens 0.26 0.26 1 PMID:16182289 -3.4.21.76 meosuc-aipm-4-nitroanilide mus musculus 7.2 7.2 1 PMID:16182289 -3.4.21.76 meosuc-ala-ala-pro-val-p-nitroanilide homo sapiens 30.0 30.0 1 PMID:12538645 -3.4.21.76 meosuc-lys(2-picolinoyl)-ala-pro-val-p-nitroanilide homo sapiens 138.0 138.0 1 PMID:12538645 -3.4.21.76 meosuc-lys(2-picolinoyl)-tyr-asp-ala-p-nitroanilide homo sapiens 192.0 192.0 1 PMID:12538645 -3.4.21.76 meosuc-lys(2-picolinoyl)-tyr-asp-val-p-nitroanilide homo sapiens 660.0 660.0 1 PMID:12538645 -3.4.21.76 suc-aaa-4-nitroanilide mus musculus 0.031 0.031 1 PMID:16182289 -3.4.21.76 suc-aapl-4-nitroanilide mus musculus 0.16 0.16 1 PMID:16182289 -3.4.21.76 suc-aapv-4-nitroanilide homo sapiens 0.37 0.37 1 PMID:16182289 -3.4.21.76 suc-aapv-4-nitroanilide mus musculus 11.2 11.2 1 PMID:16182289 -3.4.21.76 suc-ala-ala-asp-val-p-nitroanilide homo sapiens 84.0 84.0 1 PMID:12538645 -3.4.21.76 suc-ala-ala-glu-val-p-nitroanilide homo sapiens 60.0 60.0 1 PMID:12538645 -3.4.21.76 suc-ala-ala-pro-2-aminobutyric acid-p-nitroanilide homo sapiens 30.0 30.0 1 PMID:12538645 -3.4.21.76 suc-ala-ala-pro-ala-p-nitroanilide homo sapiens 13.8 13.8 1 PMID:12538645 -3.4.21.76 suc-ala-ala-pro-ile-p-nitroanilide homo sapiens 16.2 16.2 1 PMID:12538645 -3.4.21.76 suc-ala-ala-pro-nva-p-nitroanilide homo sapiens 5.4 5.4 1 PMID:12538645 -3.4.21.76 suc-ala-ala-pro-val-p-nitroanilide homo sapiens 12.0 12.0 1 PMID:12538645 -3.4.21.76 suc-ala-tyr-leu-val-p-nitroanilide homo sapiens 6.0 6.0 1 PMID:12538645 -3.4.21.76 suc-leu-val-glu-ala-p-nitroanilide homo sapiens 22.2 15.1 2 PMID:12538645 -3.4.21.76 succinyl-ala-ala-norvaline thiobenzyl ester homo sapiens 19.0 19.0 1 PMID:1551417 -3.4.21.76 tert-butyloxycarbonyl-ala-ala-ala thiobenzyl ester homo sapiens 10.1 10.1 1 PMID:1551417 -3.4.21.76 tert-butyloxycarbonyl-ala-ala-ile thiobenzyl ester homo sapiens 1.9 1.9 1 PMID:1551417 -3.4.21.76 tert-butyloxycarbonyl-ala-ala-met thiobenzyl ester homo sapiens 12.2 12.2 1 PMID:1551417 -3.4.21.76 tert-butyloxycarbonyl-ala-ala-norvaline thiobenzyl ester homo sapiens 63.3 63.3 1 PMID:1551417 -3.4.21.76 tert-butyloxycarbonyl-ala-ala-val thiobenzyl ester homo sapiens 10.4 10.4 1 PMID:1551417 -3.4.21.77 4-morpholinecarbonyl-hssklq-7-amido-4-methylcoumarin homo sapiens 0.19 0.19 1 PMID:25237904 -3.4.21.77 arg-pro-tyr 4-nitroanilide homo sapiens 0.028 0.028 1 PMID:1702714 -3.4.21.77 lys-val-tyr 4-nitroanilide homo sapiens 0.022 0.022 1 PMID:1702714 -3.4.21.77 meo-suc-arg-pro-tyr-4-nitroanilide homo sapiens 0.75 0.75 1 PMID:25237904 -3.4.21.77 n-succinyl-l-ala-l-ala-l-pro-l-phe 4-nitroanilide homo sapiens 0.075 0.075 1 PMID:2422647 -3.4.21.78 benzyloxycarbonyl-arg thiobenzyl ester homo sapiens 8.8 8.8 1 PMID:1998680 -3.4.21.78 benzyloxycarbonyl-arg thiobenzyl ester mus musculus 83.0 83.0 1 PMID:1998680 -3.4.21.78 benzyloxycarbonyl-gly-arg thiobenzyl ester homo sapiens 5.83 5.83 1 PMID:1998680 -3.4.21.78 benzyloxycarbonyl-gly-arg thiobenzyl ester mus musculus 59.0 59.0 1 PMID:1998680 -3.4.21.78 benzyloxycarbonyl-lys thiobenzyl ester mus musculus 21.0 21.0 1 PMID:1998680 -3.4.21.78 benzyloxycarbonyl-lys-thiobenzyl ester homo sapiens 3.1 3.1 1 PMID:1998680 -3.4.21.78 boc-ala-ala-arg-sbzl homo sapiens 4980.0 4980.0 1 PMID:9256474 -3.4.21.78 boc-trp-arg-sbzl homo sapiens 3960.0 3960.0 1 PMID:9256474 -3.4.21.78 tert-butyloxycarbonyl-ala-ala-arg thiobenzyl ester mus musculus 45.0 45.0 1 PMID:1998680 -3.4.21.78 z-arg-sbzl homo sapiens 30400.0 30380.0 2 PMID:9256474 -3.4.21.78 z-lys-sbzl homo sapiens 22140.0 22120.0 2 PMID:9256474 -3.4.21.79 2-aminobenzoyl-iepdssmek-dnp homo sapiens 4.4 4.4 1 PMID:11278311 -3.4.21.79 2-aminobenzoyl-iepdssmesk-dnp homo sapiens 4.4 4.4 1 PMID:11278311 -3.4.21.79 2-aminobenzoyl-vvadssmask-dnp homo sapiens 3.7 3.7 1 PMID:11278311 -3.4.21.79 2-aminobenzoyl-vvadssmesk-dnp homo sapiens 1.5 1.5 1 PMID:11278311 -3.4.21.79 2-aminobenzoyl-vvaessmesk-dnp homo sapiens 0.6 0.6 1 PMID:11278311 -3.4.21.79 abz-iepdssmesk-2,4-dinitrophenyl homo sapiens 4.4 4.4 1 PMID:14752093 -3.4.21.79 acetyl-ietd-p-nitroanilide homo sapiens 5.23 4.785 2 PMID:16336214 -3.4.21.79 boc-ala-ala-asp-sbzl homo sapiens 18.0 12.0 3 PMID:10425174;PMID:9480818 -3.4.21.79 boc-ala-ala-asp-sbzl mus musculus 16.0 16.0 1 PMID:9480818 -3.4.21.79 iepd-p-nitroanilide homo sapiens 5.0 4.95 2 PMID:15596356 -3.4.21.79 leed-p-nitroanilide homo sapiens 0.22 0.185 2 PMID:15596356 -3.4.21.79 nalpha-tert-butyloxycarbonyl-ala-ala-asp thiobenzyl ester mus musculus 116.0 116.0 1 PMID:1998680 -3.4.21.79 nalpha-tert-butyloxycarbonyl-ala-ala-met thiobenzyl ester mus musculus 24.0 24.0 1 PMID:1998680 -3.4.21.79 nalpha-tert-butyloxycarbonyl-l-ala-l-ala-l-asp thiobenzyl ester homo sapiens 11.0 11.0 1 PMID:1985927 -3.4.21.79 veid-p-nitroanilide homo sapiens 0.72 0.51 2 PMID:15596356 -3.4.21.80 acetyl-ala-ala-tyr-4-methylcoumarin 7-amide streptomyces griseus 0.04 0.04 1 PMID:3936849 -3.4.21.80 acetyl-pro-ala-leu-phe-nh2 streptomyces griseus 5.1 5.1 1 PMID:6768556 -3.4.21.80 acetyl-pro-ala-pro-phe-leu-nh2 streptomyces griseus 20.0 20.0 1 PMID:413567 -3.4.21.80 acetyl-pro-ala-pro-phe-nh2 streptomyces griseus 5.8 5.8 1 PMID:413567;PMID:6768556 -3.4.21.80 acetyl-pro-ala-pro-phe-tyr-nh2 streptomyces griseus 56.8 56.8 1 PMID:413567 -3.4.21.80 acetyl-pro-ala-pro-trp-nh2 streptomyces griseus 0.1 0.1 1 PMID:413567 -3.4.21.80 acetyl-pro-ala-pro-tyr-nh2 streptomyces griseus 10.1 10.1 1 PMID:413567 -3.4.21.80 succinyl-ala-ala-pro-phe 4-nitroanilide streptomyces griseus 285.0 285.0 1 PMID:3936849 -3.4.21.80 succinyl-ala-ala-pro-phe-4-methylcoumarin 7-amide streptomyces griseus 6.9 6.9 1 PMID:3936849 -3.4.21.81 acetyl-ala-ala-tyr-4-methylcoumarin 7-amide streptomyces griseus 0.04 0.04 1 PMID:3936849 -3.4.21.81 acetyl-pro-ala-leu-phe-nh2 streptomyces griseus 7.1 7.1 1 PMID:6768556 -3.4.21.81 acetyl-pro-ala-pro-phe-nh2 streptomyces griseus 6.7 6.7 1 PMID:6768556 -3.4.21.81 suc-aapf-p-nitroanilide streptomyces griseus 1884.0 1882.0 2 PMID:10712933 -3.4.21.81 succinyl-ala-ala-pro-phe 4-nitroanilide streptomyces griseus 153.0 153.0 1 PMID:3936849 -3.4.21.81 succinyl-ala-ala-pro-phe-7-amido-4-methylcoumarin streptomyces griseus 3.3 3.3 1 PMID:3936849 -3.4.21.82 tert-butyloxycarbonyl-ala-ala-ala-glu 4-nitroanilide streptomyces griseus 473.0 473.0 1 PMID:1794975 -3.4.21.82 tert-butyloxycarbonyl-ala-ala-gly-glu 4-nitroanilide streptomyces griseus 30.0 30.0 1 PMID:1794975 -3.4.21.82 tert-butyloxycarbonyl-ala-ala-leu-glu-4-nitroanilide streptomyces griseus 179.0 179.0 1 PMID:1794975 -3.4.21.82 tert-butyloxycarbonyl-ala-ala-phe-glu 4-nitroanilide streptomyces griseus 365.0 365.0 1 PMID:1794975 -3.4.21.82 tert-butyloxycarbonyl-ala-ala-pro-glu 4-nitroanilide streptomyces griseus 5390.0 5390.0 1 PMID:1794975 -3.4.21.82 tert-butyloxycarbonyl-ala-leu-pro-glu 4-nitroanilide streptomyces griseus 500.0 500.0 1 PMID:1794975 -3.4.21.82 tert-butyloxycarbonyl-ala-phe-pro-glu 4-nitroanilide streptomyces griseus 381.0 381.0 1 PMID:1794975 -3.4.21.82 tert-butyloxycarbonyl-ala-pro-glu 4-nitroanilide streptomyces griseus 182.0 182.0 1 PMID:1794975 -3.4.21.83 2-aminobenzoyl-adgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 4.8 4.8 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aegrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 5.2 5.2 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-afgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 37.0 37.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-afgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 5.2 5.2 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agdrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 3.0 3.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agergagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 1.8 1.8 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agfrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 22.0 22.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agfrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 9.7 9.7 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrdagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 15.0 15.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrdagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 15.0 15.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggreagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 13.0 13.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggreagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 15.0 15.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrfagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 11.0 11.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrfagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 24.0 24.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgadq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 17.0 17.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgaeq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 6.7 6.7 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgafq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 68.0 68.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgafq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 15.0 15.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 5.9 5.9 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 5.2 5.2 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgahq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 25.0 19.5 2 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgaiq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 55.0 55.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgaiq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 6.9 6.9 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgalq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 47.0 47.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgalq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 23.0 23.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgamq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 20.0 20.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgamq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 15.0 15.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrganq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 31.0 31.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrganq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 17.0 17.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgapq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 3.1 3.1 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgapq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 1.8 1.8 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgaqq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 51.0 51.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgaqq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 6.5 6.5 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgasq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 27.0 18.2 2 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgatq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 37.0 37.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgatq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 48.0 48.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgavq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 36.0 36.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgavq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 44.0 44.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgayq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 46.0 33.0 2 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgdgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 12.0 12.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgdgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 4.4 4.4 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgegq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 12.0 12.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgegq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 33.0 33.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgfgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 15.0 15.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgfgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 36.0 36.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgggqg-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 13.0 13.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgggqg-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 11.0 11.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrghgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 17.0 17.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrghgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 16.0 16.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgigq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 28.0 28.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgigq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 29.0 29.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrglgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 25.0 25.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrglgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 62.0 62.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgmgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 11.0 11.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgmgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 54.0 54.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgngq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 11.0 11.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgngq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 7.3 7.3 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgpgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 7.5 7.5 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgpgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 5.6 5.6 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgqgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 9.2 9.2 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgqgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 14.0 14.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgsgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 9.8 9.8 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgsgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 23.0 23.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgtgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 17.0 17.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgtgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 19.0 19.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgvgq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 53.0 46.5 2 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgygq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 20.0 20.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrgygq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 23.0 23.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrhagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 9.2 9.2 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrhagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 27.0 27.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggriagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 4.0 4.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggriagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 3.1 3.1 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrlagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 4.1 4.1 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrlagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 6.0 6.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrmagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 19.0 19.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrmagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 17.0 17.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrnagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 14.0 14.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrnagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 14.0 14.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrqagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 12.0 12.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrqagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 11.0 11.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrsagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 12.0 12.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrsagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 21.0 21.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrtagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 12.0 12.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrtagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 11.0 11.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrvagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 2.6 2.6 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggrvagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 4.8 4.8 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggryagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 13.0 13.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aggryagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 11.0 11.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aghrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 12.0 12.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agirgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 6.6 6.6 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agirgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 13.0 13.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agkrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 13.0 13.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agkrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 18.0 18.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aglrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 19.0 19.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aglrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 15.0 15.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agmrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 24.0 24.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agmrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 13.0 13.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agnrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 7.1 7.1 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agnrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 7.8 7.8 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agprgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 12.0 12.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agprgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 3.6 3.6 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agqrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 10.0 10.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agqrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 16.0 16.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agsrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 1.7 1.7 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agsrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 0.6 0.6 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agtrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 19.0 19.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agtrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 27.0 27.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agvrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 4.9 4.9 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agvrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 1.4 1.4 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agyrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 24.0 24.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-agyrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 12.0 12.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-ahgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 21.0 21.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-ahgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 19.0 19.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aigrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 35.0 35.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aigrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 23.0 23.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-algrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 29.0 29.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-algrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 14.0 14.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-amgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 39.0 39.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-amgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 23.0 23.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-angrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 15.0 15.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-apgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 4.4 4.4 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-apgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 2.2 2.2 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aqgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 42.0 42.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aqgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 13.0 13.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-asgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 41.0 41.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-asgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 17.0 17.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-atgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 30.0 30.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-atgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 30.0 30.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-avgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 45.0 45.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-avgrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 13.0 13.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aygrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma brucei 47.0 47.0 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-aygrgagq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 8.1 8.1 1 PMID:12737623 -3.4.21.83 2-aminobenzoyl-thr-arg cit-phe(no2)-ser-leu-nh2 escherichia coli 294.0 294.0 1 PMID:11900553 -3.4.21.83 2-aminobenzoyl-thr-arg-arg phe(no2)-ser-leu-nh2 escherichia coli 1420.0 1391.0 6 PMID:11900553 -3.4.21.83 2-aminobenzoyl-thr-cit-arg phe(no2)-ser-leu-nh2 escherichia coli 1220.0 1219.0 2 PMID:11900553 -3.4.21.83 3-(2-furyl)acryloyl-tyr-lys-arg trypanosoma evansi 18.0 15.0 2 PMID:15644339 -3.4.21.83 acetyl-l-leu-l-leu-l-arg-4-nitroanilide serratia proteamaculans 13.9 10.75 2 PMID:21585325 -3.4.21.83 acetyl-l-leu-l-lys-l-arg-4-nitroanilide serratia proteamaculans 32.0 28.15 2 PMID:21585325 -3.4.21.83 acetyl-tyr 4-nitroanilide escherichia coli 1.5 1.5 1 PMID:342237 -3.4.21.83 ala-phe-lys-7-amido-4-methylcoumarin trypanosoma evansi 34.0 28.5 2 PMID:15644339 -3.4.21.83 arg-7-amido-4-methylcoumarin trypanosoma evansi 2.0 1.5 2 PMID:15644339 -3.4.21.83 arg-arg-2-naphthylamide trypanosoma evansi 30.0 25.5 2 PMID:15644339 -3.4.21.83 arg-arg-arg trypanosoma evansi 38.0 33.5 2 PMID:15644339 -3.4.21.83 benzoyl-arg 2-naphthylamide escherichia coli 0.024 0.024 1 PMID:1769955 -3.4.21.83 benzoyl-arg-4-nitroanilide escherichia coli 11300.0 6851.0 6 PMID:10569938 -3.4.21.83 benzoyl-arg-7-amido-4-methylcoumarin trypanosoma brucei 13.3 13.3 1 PMID:23946505 -3.4.21.83 benzoyl-arg-beta-naphthylamide escherichia coli 4850.0 4849.0 2 PMID:10569938 -3.4.21.83 benzoyl-gly-gly-l-arg-7-amido-4-methylcoumarin leishmania donovani 6830.0 6830.0 1 PMID:20961853 -3.4.21.83 benzoyl-gly-l-pro-l-arg-7-amido-4-methylcoumarin leishmania donovani 4250.0 4250.0 1 PMID:20961853 -3.4.21.83 benzoyl-l-arg-7-amido-4-methylcoumarin leishmania major 0.016 0.016 1 PMID:20926390 -3.4.21.83 benzoyl-l-arg-7-amido-4-methylcoumarin trypanosoma brucei 8.29 8.29 1 PMID:19819899 -3.4.21.83 benzoyl-l-pro-l-phe-l-arg-4-nitroanilide serratia proteamaculans 201.7 111.44999999999999 2 PMID:21585325 -3.4.21.83 benzoyl-lys 2-naphthylamide escherichia coli 4.4 4.4 1 PMID:1769955 -3.4.21.83 benzoyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin trypanosoma brucei 8.29 8.29 1 PMID:23946505 -3.4.21.83 benzyloxycarbonyl-arg-7-amido-4-methylcoumarin trypanosoma evansi 26.0 21.5 2 PMID:15644339 -3.4.21.83 benzyloxycarbonyl-arg-arg-4-methylcoumarin 7-amide salmonella enterica 2040.0 2040.0 1 PMID:12029050 -3.4.21.83 benzyloxycarbonyl-arg-arg-4-nitroanilide serratia proteamaculans 36.35 19.485 2 PMID:34681120 -3.4.21.83 benzyloxycarbonyl-arg-arg-7-amido-4-methylcoumarin trypanosoma evansi 64.0 61.5 2 PMID:15644339 -3.4.21.83 benzyloxycarbonyl-arg-thr-lys-arg-7-amido-4-methylcoumarin trypanosoma brucei 5.16 5.16 1 PMID:23946505 -3.4.21.83 benzyloxycarbonyl-gly-arg-4-methylcoumarin 7-amide salmonella enterica 900.0 900.0 1 PMID:12029050 -3.4.21.83 benzyloxycarbonyl-gly-gly-arg-4-methylcoumarin 7-amide salmonella enterica 1500.0 1500.0 1 PMID:12029050 -3.4.21.83 benzyloxycarbonyl-gly-gly-arg-7-amido-4-methylcoumarin trypanosoma evansi 48.0 40.5 2 PMID:15644339 -3.4.21.83 benzyloxycarbonyl-gly-l-arg-l-arg-7-amido-4-methylcoumarin leishmania major 0.013 0.013 1 PMID:20926390 -3.4.21.83 benzyloxycarbonyl-l-arg-7-amido-4-methylcoumarin trypanosoma brucei 13.3 13.3 1 PMID:19819899 -3.4.21.83 benzyloxycarbonyl-l-argininyl-l-arginyl-4-nitroanilide serratia proteamaculans 33.975 33.975 1 PMID:28554571 -3.4.21.83 benzyloxycarbonyl-l-lysyl-l-arginyl-4-nitroanilide serratia proteamaculans 52.34 52.34 1 PMID:28554571 -3.4.21.83 benzyloxycarbonyl-leu-lys-arg-7-amido-4-methylcoumarin trypanosoma brucei 3.36 3.36 1 PMID:23946505 -3.4.21.83 benzyloxycarbonyl-lys-4-methylcoumarin 7-amide salmonella enterica 420.0 420.0 1 PMID:12029050 -3.4.21.83 benzyloxycarbonyl-lys-arg-4-nitroanilide serratia proteamaculans 50.76 30.32 2 PMID:34681120 -3.4.21.83 benzyloxycarbonyl-phe-arg-4-methylcoumarin 7-amide salmonella enterica 1260.0 1260.0 1 PMID:12029050 -3.4.21.83 benzyloxycarbonyl-phe-arg-arg-7-amido-4-methylcoumarin trypanosoma evansi 77.0 68.0 2 PMID:15644339 -3.4.21.83 benzyloxycarbonyl-val-arg-4-methylcoumarin 7-amide salmonella enterica 900.0 900.0 1 PMID:12029050 -3.4.21.83 boc-gln-gly-arg-4-methylcoumarin 7-amide salmonella enterica 1020.0 1020.0 1 PMID:12029050 -3.4.21.83 boc-gly-arg-arg-4-methylcoumarin 7-amide salmonella enterica 1380.0 1380.0 1 PMID:12029050 -3.4.21.83 boc-gly-lys-arg-4-methylcoumarin 7-amide salmonella enterica 1200.0 1200.0 1 PMID:12029050 -3.4.21.83 boc-leu-arg-arg-4-methylcoumarin 7-amide salmonella enterica 1560.0 1560.0 1 PMID:12029050 -3.4.21.83 boc-leu-gly-arg-4-methylcoumarin 7-amide salmonella enterica 1080.0 1080.0 1 PMID:12029050 -3.4.21.83 boc-leu-gly-lys-4-methylcoumarin 7-amide salmonella enterica 960.0 960.0 1 PMID:12029050 -3.4.21.83 boc-leu-thr-arg-4-methylcoumarin 7-amide salmonella enterica 1080.0 1080.0 1 PMID:12029050 -3.4.21.83 gly-arg-2-naphthylamide trypanosoma evansi 12.0 11.5 2 PMID:15644339 -3.4.21.83 gly-gly-lys-arg trypanosoma evansi 54.0 47.0 2 PMID:15644339 -3.4.21.83 n-benzoyl-arg ethyl ester escherichia coli 197.0 197.0 1 PMID:342237 -3.4.21.83 n-benzoyl-arginine amide escherichia coli 57.0 30.25 2 PMID:342237 -3.4.21.83 n-benzyloxycarbonyl-gly-gly-l-arg-7-amido-4-methylcoumarin leishmania major 0.02 0.02 1 PMID:20926390 -3.4.21.83 n-benzyloxycarbonyl-l-arg-l-arg-7-amido-4-methylcoumarin leishmania major 0.01 0.01 1 PMID:20926390 -3.4.21.83 n-benzyloxycarbonyl-l-phe-l-arg-7-amido-4-methylcoumarin leishmania major 0.011 0.011 1 PMID:20926390 -3.4.21.83 n-benzyloxycarbonyl-lys 4-nitrophenyl ester escherichia coli 43.0 43.0 1 PMID:342237 -3.4.21.83 n-benzyloxycarbonyl-lys benzyl ester escherichia coli 55.0 55.0 1 PMID:342237 -3.4.21.83 n2-benzyloxycarbonyl-arg-arg-7-amido-4-methylcoumarin trypanosoma brucei 5.82 5.82 1 PMID:23946505 -3.4.21.83 nalpha-benzoyl-d,l-arginine-4-nitroanilide serratia proteamaculans 13.19 7.359999999999999 2 PMID:34681120 -3.4.21.83 nalpha-benzoyl-dl-arginine-4-nitroanilide serratia proteamaculans 37.7 26.1 2 PMID:21585325 -3.4.21.83 nalpha-benzoyl-dl-argininyl-4-nitroanilide serratia proteamaculans 14.35 14.35 1 PMID:28554571 -3.4.21.83 nalpha-benzyloxycarbonyl-l-lysine thiobenzyl ester serratia proteamaculans 55.5 54.65 2 PMID:21585325 -3.4.21.83 nalpha-benzyloxycarbonyl-l-phe-l-arg-4-nitroanilide serratia proteamaculans 35.2 21.6 2 PMID:21585325 -3.4.21.83 phe-arg-2-naphthylamide trypanosoma evansi 18.0 17.5 2 PMID:15644339 -3.4.21.83 phe-arg-arg trypanosoma evansi 21.0 18.5 2 PMID:15644339 -3.4.21.83 succinyl-l-ala-l-ala-l-pro-l-lys-4-nitroanilide serratia proteamaculans 1.0 1.0 1 PMID:21585325 -3.4.21.83 succinyl-l-alal-ala-l-pro-l-arg-4-nitroanilide serratia proteamaculans 1.2 0.85 2 PMID:21585325 -3.4.21.83 tert-butyloxycarbonyl-ala-arg-arg-7-amido-4-methylcoumarin trypanosoma evansi 102.0 102.0 1 PMID:15644339 -3.4.21.83 tert-butyloxycarbonyl-ala-gly-pro-arg-7-amido-4-methylcoumarin trypanosoma evansi 12.0 10.5 2 PMID:15644339 -3.4.21.83 tert-butyloxycarbonyl-gly-arg-arg-7-amido-4-methylcoumarin trypanosoma evansi 101.0 91.0 2 PMID:15644339 -3.4.21.83 tert-butyloxycarbonyl-gly-lys-arg-7-amido-4-methylcoumarin trypanosoma evansi 76.0 65.5 2 PMID:15644339 -3.4.21.83 tert-butyloxycarbonyl-leu-arg-arg-7-amido-4-methylcoumarin trypanosoma evansi 154.0 131.0 2 PMID:15644339 -3.4.21.83 tert-butyloxycarbonyl-leu-gly-arg-7-amido-4-methylcoumarin trypanosoma evansi 74.0 65.5 2 PMID:15644339 -3.4.21.83 tert-butyloxycarbonyl-leu-lys-arg-7-amido-4-methylcoumarin trypanosoma evansi 132.0 113.0 2 PMID:15644339 -3.4.21.83 tert-butyloxycarbonyl-val-gly-arg-7-amido-4-methylcoumarin trypanosoma evansi 64.0 61.0 2 PMID:15644339 -3.4.21.83 tert-butyloxycarbonyl-val-leu-lys-7-amido-4-methylcoumarin trypanosoma evansi 22.0 20.0 2 PMID:15644339 -3.4.21.83 tert-butyloxycarbonyl-val-pro-arg-7-amido-4-methylcoumarin trypanosoma evansi 12.0 10.0 2 PMID:15644339 -3.4.21.83 tos-gly-pro-arg-4-methylcoumarin 7-amide salmonella enterica 780.0 780.0 1 PMID:12029050 -3.4.21.83 tos-gly-pro-lys-4-methylcoumarin 7-amide salmonella enterica 1080.0 1080.0 1 PMID:12029050 -3.4.21.83 tosyl-arg methyl ester escherichia coli 60.0 60.0 1 PMID:342237 -3.4.21.83 tosyl-lys methyl ester escherichia coli 55.0 55.0 1 PMID:342237 -3.4.21.83 val-lys-arg-arg trypanosoma evansi 44.0 41.0 2 PMID:15644339 -3.4.21.84 n-tert-butoxycarbonyl-val-pro-arg 4-nitroanilide tachypleus tridentatus 391.0 391.0 1 PMID:2016264 -3.4.21.84 tert-butoxycarbonyl-ala-pro-arg-7-amido-4-methylcoumarin tachypleus tridentatus 72.0 72.0 1 PMID:2016264 -3.4.21.84 tert-butoxycarbonyl-asp(o-benzyl)-ala-arg 4-methylcoumarin 7-amide tachypleus tridentatus 18.0 18.0 1 PMID:2016264 -3.4.21.84 tert-butoxycarbonyl-asp(o-benzyl)-pro-arg-7-amido-4-methylcoumarin tachypleus tridentatus 75.0 75.0 1 PMID:2016264 -3.4.21.84 tert-butoxycarbonyl-gln-pro-arg 4-methylcoumarin 7-amide tachypleus tridentatus 34.0 34.0 1 PMID:2016264 -3.4.21.84 tert-butoxycarbonyl-lys(benzyloxycarbonyl)-gly-arg 4-methylcoumarin 7-amide tachypleus tridentatus 10.0 10.0 1 PMID:2016264 -3.4.21.84 tert-butoxycarbonyl-met-ala-arg 4-methylcoumarin 7-amide tachypleus tridentatus 27.0 27.0 1 PMID:2016264 -3.4.21.84 tert-butoxycarbonyl-val-pro-arg 4-methylcoumarin 7-amide tachypleus tridentatus 48.0 48.0 1 PMID:2016264 -3.4.21.89 ala-ala-phe-4-methylcoumaryl-7-amide thermococcus kodakarensis 16.0 16.0 1 PMID:16484219 -3.4.21.89 alkaline phosphatase signal peptide fused to full-length mammalian cytochrome b5 escherichia coli 11.0 11.0 1 PMID:11738082 -3.4.21.89 decanoyl-ltptakaaskidd-oh staphylococcus aureus 418.0 242.5 2 PMID:12750021 -3.4.21.89 fsasala-ki escherichia coli 0.03 0.03 1 PMID:10891078 -3.4.21.89 fsasalaki escherichia coli 1.44 1.44 1 PMID:15195997 -3.4.21.89 phe-ser-ala-ser-ala-leu-ala-lys-ile escherichia coli 0.024 0.022600000000000002 2 PMID:7629019;PMID:7845215 -3.4.21.89 phe-ser-ala-ser-ala-leu-ala-lys-ile-nh2 escherichia coli 0.033 0.033 1 PMID:7845215 -3.4.21.89 preprotein substrate pona bacillus subtilis 0.034 0.034 1 PMID:10982814 -3.4.21.89 preprotein substrate pona escherichia coli 44.0 44.0 1 PMID:10982814 -3.4.21.89 pro-ompa-nuclease escherichia coli 8.73 5.0 3 PMID:9194173;PMID:9464569 -3.4.21.89 pro-ompa-nuclease a escherichia coli 8.73 5.865 2 PMID:7696258;PMID:7837264 -3.4.21.89 y-no2-fsasalakik-2-aminobenzoyl-nh2 escherichia coli 1.5 0.755 2 PMID:10891078 -3.4.21.89 yfsasala-4-methylcoumarin 7-amide escherichia coli 0.000528 0.000407 5 PMID:10891078 -3.4.21.9 a4-mutant trypsinogen homo sapiens 11.2 11.2 1 PMID:15970597 -3.4.21.9 angiotensin ii bos taurus 0.4 0.4 1 PMID:15377272 -3.4.21.9 benzoyl-arg ethyl ester sus scrofa 28.4 28.4 1 PMID:5570436 -3.4.21.9 benzyloxycarbonyl-phe-arg-4-methylcoumarin 7-amide sus scrofa 262.0 262.0 1 PMID:10220588 -3.4.21.9 benzyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin oryzias latipes 0.64 0.64 1 PMID:24481630 -3.4.21.9 bovine trypsinogen bos taurus 6.9 5.45 2 PMID:15970597 -3.4.21.9 formyl-ala-phe-arg-4-nitroanilide bos taurus 26.3 26.3 1 PMID:21515380 -3.4.21.9 formyl-ala-phe-arg-4-nitroanilide homo sapiens 23.5 23.5 1 PMID:21515380 -3.4.21.9 formyl-ala-phe-lys-4-nitroanilide bos taurus 15.4 15.4 1 PMID:21515380 -3.4.21.9 formyl-ala-phe-lys-4-nitroanilide homo sapiens 18.2 18.2 1 PMID:21515380 -3.4.21.9 g5dkf(no2)g bos taurus 17.33 9.149999999999999 2 PMID:15377272 -3.4.21.9 g5dkf(no2)g homo sapiens 17.33 9.149999999999999 2 PMID:16271029 -3.4.21.9 gd4k 2-naphthylamide homo sapiens 67250.0 33637.45 2 PMID:21777516;PMID:34026576 -3.4.21.9 gd4k 7-amido-4-methylcoumarin homo sapiens 64.8 64.8 1 PMID:21777516 -3.4.21.9 gd4kf(no2)g bos taurus 17.83 9.409999999999998 2 PMID:15377272 -3.4.21.9 gd4kf(no2)g homo sapiens 17.83 9.409999999999998 2 PMID:16271029 -3.4.21.9 gd4knfa bos taurus 16.67 8.82 2 PMID:15377272 -3.4.21.9 gd4r-4-nitroanilide homo sapiens 45.0 45.0 1 PMID:23436726 -3.4.21.9 gddddk-2-naphthylamide homo sapiens 115.0 103.5 2 PMID:23917033 -3.4.21.9 gddddk-2-naphthylamide oryzias latipes 27.9 27.9 1 PMID:24481630 -3.4.21.9 gddddk-4-nitroanilide homo sapiens 135.0 135.0 1 PMID:23436726 -3.4.21.9 gly-asp-asp-asp-asp-2-naphthylamide sus scrofa 520.0 520.0 1 PMID:10220588 -3.4.21.9 gly-asp-asp-asp-asp-lys-2-naphthylamide bos taurus 49.3 22.450000000000003 4 PMID:10493881;PMID:12135563;PMID:21515380;PMID:9395456 -3.4.21.9 gly-asp-asp-asp-asp-lys-2-naphthylamide homo sapiens 121.0 116.5 4 PMID:12963350;PMID:21515380 -3.4.21.9 gly-l-asp-l-asp-l-asp-l-asp-l-lys-2-naphthylamide homo sapiens 58.38 58.38 1 PMID:27826720 -3.4.21.9 glycyl-tetra-l-aspartyl-l-lysine beta-naphthylamide homo sapiens 21.5 16.67 3 PMID:16271029 -3.4.21.9 human cationic trypsinogen bos taurus 8.8 8.8 1 PMID:15970597 -3.4.21.9 human cationic trypsinogen homo sapiens 35.1 2.3 3 PMID:15970597 -3.4.21.9 ltaeeka bos taurus 0.49 0.49 1 PMID:15377272 -3.4.21.9 ltaeeka homo sapiens 0.07 0.07 1 PMID:16271029 -3.4.21.9 mltaeekaa bos taurus 25.17 25.17 1 PMID:15377272 -3.4.21.9 n-alpha-benzyloxycarbonyl-l-lysine thiobenzyl ester homo sapiens 111.0 111.0 1 PMID:16271029 -3.4.21.9 n2-benzoyl-l-arg ethyl ester bos taurus 53.0 53.0 1 PMID:762166 -3.4.21.9 prad4kp26 bos taurus 2.62 2.62 1 PMID:15377272 -3.4.21.9 t-butyloxycarbonyl-e(benzyl ester)-ala-arg-7-amido-4-methylcoumarin oryzias latipes 0.34 0.34 1 PMID:24481630 -3.4.21.9 thiobenzyl benzyloxy-carbonyl-l-lysinate bos taurus 129.0 129.0 1 PMID:21515380 -3.4.21.9 thiobenzyl benzyloxy-carbonyl-l-lysinate homo sapiens 133.0 133.0 2 PMID:12963350;PMID:21515380 -3.4.21.9 thiobenzyl benzyloxycarbonyl-l-lysinate bos taurus 129.0 129.0 1 PMID:10493881 -3.4.21.9 tosyl-arg methyl ester bos taurus 12.0 12.0 1 PMID:762166 -3.4.21.9 tosyl-arg methyl ester sus scrofa 8.1 8.1 1 PMID:5570436 -3.4.21.9 tosyl-lys methyl ester bos taurus 12.0 12.0 1 PMID:762166 -3.4.21.9 trypsinogen bos taurus 6.9 4.0 5 PMID:762166;PMID:889800;PMID:9395456 -3.4.21.9 trypsinogen homo sapiens 2.8 2.8 1 PMID:564906 -3.4.21.9 trypsinogen sus scrofa 4.8 3.55 2 PMID:5570436;PMID:564906 -3.4.21.9 val-(ala)2-(asp)2-lys-ile-val-gly sus scrofa 15.9 15.9 1 PMID:18323639 -3.4.21.9 val-(ala)2-asp-ala-lys-ile-val-gly sus scrofa 14.1 14.1 1 PMID:18323639 -3.4.21.9 val-(ala)3-asp-lys-ile-val-gly sus scrofa 17.0 17.0 1 PMID:18323639 -3.4.21.9 val-(asp)2-ala-asp-lys-ile-val-gly sus scrofa 14.3 14.3 1 PMID:18323639 -3.4.21.9 val-(asp)3-ala-lys-ile-val-gly sus scrofa 14.6 14.6 1 PMID:18323639 -3.4.21.9 val-(asp)3-glu-lys-ile-val-gly sus scrofa 8.0 8.0 1 PMID:18323639 -3.4.21.9 val-(asp)4-arg-ile-val-gly sus scrofa 13.6 13.6 1 PMID:18323639 -3.4.21.9 val-(asp)4-lys-ile-val-gly sus scrofa 20.0 20.0 1 PMID:18323639 -3.4.21.9 val-ala-(asp)3-lys-ile-val-gly sus scrofa 17.8 17.8 1 PMID:18323639 -3.4.21.9 val-ala-asp-ala-asp-lys-ile-val-gly sus scrofa 23.0 23.0 1 PMID:18323639 -3.4.21.9 val-asp-(ala)2-asp-lys-ile-val-gly sus scrofa 28.1 28.1 1 PMID:18323639 -3.4.21.9 val-asp-(ala)3-lys-ile-val-gly sus scrofa 9.1 9.1 1 PMID:18323639 -3.4.21.9 val-asp-ala-(asp)2-lys-ile-val-gly sus scrofa 14.7 14.7 1 PMID:18323639 -3.4.21.9 val-asp-ala-asp-ala-lys-ile-val-gly sus scrofa 10.3 10.3 1 PMID:18323639 -3.4.21.9 wddkg bos taurus 0.54 0.54 1 PMID:15377272 -3.4.21.9 wddrg bos taurus 0.68 0.68 1 PMID:15377272 -3.4.21.9 z-lys-sbzl homo sapiens 336.0 336.0 1 PMID:23436726 -3.4.21.91 abz-agrk-sltny-amide dengue virus type 2 0.005 0.005 1 PMID:16489931 -3.4.21.91 abz-agrk-sny-amide dengue virus type 2 0.001 0.001 1 PMID:16489931 -3.4.21.91 abz-agrks-3-nitrotyrosine-amide dengue virus type 2 0.001 0.001 1 PMID:16489931 -3.4.21.91 abz-agrkslt-3-nitrotyrosine-amide dengue virus type 2 0.005 0.005 1 PMID:16489931 -3.4.21.91 abz-kkqr-sagmny-amide dengue virus type 2 0.0967 0.0967 1 PMID:16489931 -3.4.21.91 abz-kkqragvl-3-nitrotyrosine-amide dengue virus type 2 0.0967 0.0967 1 PMID:16489931 -3.4.21.91 abz-skkr-agvlny-amide dengue virus type 2 0.0045 0.0045 1 PMID:16489931 -3.4.21.91 abz-skkr-sagmny-amide dengue virus type 2 0.045 0.045 1 PMID:16489931 -3.4.21.91 abz-skkragvl-3-nitrotyrosine-amide dengue virus type 2 0.0045 0.0045 1 PMID:16489931 -3.4.21.91 abz-skkrsagm-3-nitrotyrosine-amide dengue virus type 2 0.045 0.045 1 PMID:16489931 -3.4.21.91 ac-arg-lys-lys-arg-7-amido-4-carbamoylmethylcoumarin zika virus 1.08 1.08 1 PMID:28034744 -3.4.21.91 ac-d-arg-lys-orn-arg(me)-7-amido-4-carbamoylmethylcoumarin zika virus 5.43 5.43 1 PMID:28034744 -3.4.21.91 ac-d-arg-lys-orn-arg-7-amido-4-carbamoylmethylcoumarin zika virus 4.64 4.64 1 PMID:28034744 -3.4.21.91 ac-d-lys-lys-orn-arg-7-amido-4-carbamoylmethylcoumarin zika virus 7.99 7.99 1 PMID:28034744 -3.4.21.91 ac-nle-lys-lys-arg-7-amido-4-carbamoylmethylcoumarin zika virus 4.4 4.4 1 PMID:28034744 -3.4.21.91 acetyl-nle-lys-arg-arg-4-methylcoumarin 7-amide dengue virus 0.112 0.112 1 PMID:24228881 -3.4.21.91 benzoyl-nkrr-7-amido-4-carbamoylmethylcoumarin yellow fever virus 0.24 0.24 1 PMID:31931019 -3.4.21.91 benzoyl-nle-lys-arg-arg-4-methylcoumarin 7-amide dengue virus 2.9 2.9 1 PMID:15932883 -3.4.21.91 benzoyl-nle-lys-arg-arg-7-amido-3-carbamoylmethyl-4-methylcoumarin dengue virus 2.8 1.005 4 PMID:15932883 -3.4.21.91 benzoyl-nle-lys-arg-arg-thiobenzylester dengue virus 300.0 300.0 1 PMID:15932883 -3.4.21.91 benzoyl-nle-lys-thr-arg-7-amido-3-carbamoylmethyl-4-methylcoumarin dengue virus 4.9 1.25 4 PMID:15932883 -3.4.21.91 benzoyl-nle-thr-arg-arg-7-amido-3-carbamoylmethyl-4-methylcoumarin dengue virus 1.1 0.6699999999999999 4 PMID:15932883 -3.4.21.91 benzoyl-thr-lys-arg-arg-7-amido-3-carbamoylmethyl-4-methylcoumarin dengue virus 0.43 0.15000000000000002 4 PMID:15932883 -3.4.21.91 benzoyl-thr-thr-arg-arg-7-amido-3-carbamoylmethyl-4-methylcoumarin dengue virus 0.48 0.27 4 PMID:15932883 -3.4.21.91 boc-gly-arg-arg-7-amido-4-methylcoumarin yellow fever virus 0.034 0.034 1 PMID:17622626 -3.4.21.91 bz-arg-arg-4-methylcoumaryl-7-amide dengue virus 0.109 0.109 1 PMID:17184724 -3.4.21.91 bz-nle-lys-arg-arg-7-amido-4-methylcoumarin yellow fever virus 0.111 0.111 1 PMID:17622626 -3.4.21.91 faegrrgaaevlq yellow fever virus 0.001 0.001 1 PMID:21419753 -3.4.21.91 gly-arg-arg-4-methylcoumarin 7-amide dengue virus type 2 0.02 0.02 1 PMID:15564480 -3.4.21.91 klaqrrvfhgvaq yellow fever virus 0.003 0.003 1 PMID:21419753 -3.4.21.91 l-pglu-l-arg-l-thr-l-lys-l-arg-7-amido-4-methylcoumarin west nile virus 6.3 6.3 1 PMID:20156198 -3.4.21.91 mktgrrgsangkq yellow fever virus 0.012 0.012 1 PMID:21419753 -3.4.21.91 n-(2-aminobenzoyl)-l-valyl-l-lysyl-l-lysyl-n-(3-carbamoyl-4-nitrophenyl)-l-argininamide zika virus 343.73 184.835 2 PMID:27714789 -3.4.21.91 n-acetyl-gly-arg-arg-7-amido-4-methylcoumarin dengue virus type 2 0.09 0.07 2 PMID:30472839 -3.4.21.91 n-alpha-benzoyl-l-arginine-p-nitroanilide alkhumra hemorrhagic fever virus 0.015 0.01005 2 PMID:17030861 -3.4.21.91 n-benzoyl-3-(4-aminocyclohexyl)-l-ala-l-arg-4-methylcoumaryl-7-amide dengue virus 0.013 0.013 1 PMID:17184724 -3.4.21.91 n-benzoyl-3-(4-piperidinyl)-l-ala-l-arg-4-methylcoumaryl-7-amide dengue virus 0.014 0.014 1 PMID:17184724 -3.4.21.91 n-benzoyl-3-(trans-aminomethylcyclohexyl)-l-ala-l-arg-4-methylcoumaryl-7-amide dengue virus 0.172 0.172 1 PMID:17184724 -3.4.21.91 n-benzoyl-3-pyridyl-l-ala-l-arg-4-methylcoumaryl-7-amide dengue virus 0.002 0.002 1 PMID:17184724 -3.4.21.91 n-benzoyl-4-(aminomethyl)-l-phe-l-arg-4-methylcoumaryl-7-amide dengue virus 0.013 0.013 1 PMID:17184724 -3.4.21.91 n-benzoyl-4-(aminomethyl-n-isopropyl)-l-phe-l-arg-4-methylcoumaryl-7-amide dengue virus 0.022 0.022 1 PMID:17184724 -3.4.21.91 n-benzoyl-4-(guanidino)-l-phe-l-arg-4-methylcoumaryl-7-amide dengue virus 0.035 0.035 1 PMID:17184724 -3.4.21.91 n-benzyloxycarbonyl-arg-arg-4-methylcoumaryl-7-amide dengue virus 0.11 0.11 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-agkksaq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.02 0.02 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-agkksaq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.001 0.001 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-agkrsaq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.2 0.2 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-agkrsaq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.01 0.01 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-agrksaq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.13 0.13 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-agrksaq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.005 0.005 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-agrrsaq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.21 0.21 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-agrrsaq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.061 0.061 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-akkksq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.04 0.04 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-akkksq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.004 0.004 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-akkrsq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.07 0.07 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-akkrsq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.097 0.097 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-akrksq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.04 0.04 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-akrksq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.012 0.012 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-akrrsq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 1.0 1.0 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-akrrsq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.026 0.026 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-arkksq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.05 0.05 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-arkksq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.002 0.002 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-arkrsq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.07 0.07 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-arkrsq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.06 0.06 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-arrksq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.09 0.09 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-arrksq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.005 0.005 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-arrrsq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.38 0.38 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-arrrsq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.12 0.12 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-evkkqragvlwdq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.03 0.03 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-faagrksltlnlq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.02 0.02 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-faaqrrgrigrnq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.14 0.14 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-hrrekrsvalq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.04 0.04 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-kkrsskq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.012 0.012 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-krrsskq-n-(2,4-dinitrophenyl)-ethylenediamine yellow fever virus 0.025 0.025 1 PMID:21419753 -3.4.21.91 o-aminobenzoyl-lnrrrrtagmiiq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.04 0.04 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-rtskkrswplneq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.17 0.17 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-saagrrgrigrnq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.09 0.09 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-saaqrkgrigrnq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.04 0.04 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-saaqrrgligrnq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.11 0.11 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-saaqrrgrignnq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.11 0.11 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-saaqrrgrigrlq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.16 0.16 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-saaqrrgrigrnq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.29 0.29 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-saaqrrgrilrnq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.18 0.18 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-saaqrrgrtgrnq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.34 0.34 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-saaqrrsrigrnq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.14 0.14 1 PMID:17184724 -3.4.21.91 o-aminobenzoyl-ttstrrgtgnigq-n-(2,4-dinitrophenyl)-ethylenediamine dengue virus 0.04 0.04 1 PMID:17184724 -3.4.21.91 pyroglutamic acid-arg-thr-lys-arg-7-amido-4-methylcoumarin west nile virus 6.3 6.3 1 PMID:17067286 -3.4.21.91 rifgrrsipvneq yellow fever virus 0.005 0.005 1 PMID:21419753 -3.4.21.91 saaqrrgrigrnq yellow fever virus 0.016 0.016 1 PMID:21419753 -3.4.21.91 ssrkrrshdvltq yellow fever virus 0.069 0.069 1 PMID:21419753 -3.4.21.91 t-butoxycarbonyl-arg-val-arg-arg-7-amido-4-methylcoumarin west nile virus 0.22 0.22 1 PMID:17067286 -3.4.21.91 t-butyloxycarbonyl-glycyl-l-arginyl-l-arginine-4-methylcoumaryl-7-amide bussuquara virus 0.073 0.073 1 PMID:16504332 -3.4.21.91 t-butyloxycarbonyl-glycyl-l-arginyl-l-arginine-4-methylcoumaryl-7-amide dengue virus type 1 0.101 0.101 1 PMID:16504332 -3.4.21.91 t-butyloxycarbonyl-glycyl-l-arginyl-l-arginine-4-methylcoumaryl-7-amide dengue virus type 3 0.163 0.163 1 PMID:16504332 -3.4.21.91 t-butyloxycarbonyl-glycyl-l-arginyl-l-arginine-4-methylcoumaryl-7-amide langat virus 0.007 0.007 1 PMID:16504332 -3.4.21.91 t-butyloxycarbonyl-glycyl-l-arginyl-l-arginine-4-methylcoumaryl-7-amide st. louis encephalitis virus 0.075 0.075 1 PMID:16504332 -3.4.21.91 t-butyloxycarbonyl-glycyl-l-arginyl-l-arginine-4-methylcoumaryl-7-amide yellow fever virus 0.044 0.044 1 PMID:16504332 -3.4.21.91 t-butyloxycarbonyl-glycyl-l-arginyl-l-arginine-4-methylcoumaryl-7-amide zika virus 0.013 0.013 1 PMID:16504332 -3.4.21.91 t-butyloxycarbonyl-glycyl-l-lysyl-l-arginine-4-methylcoumaryl-7-amide bussuquara virus 0.039 0.039 1 PMID:16504332 -3.4.21.91 t-butyloxycarbonyl-glycyl-l-lysyl-l-arginine-4-methylcoumaryl-7-amide dengue virus type 1 0.153 0.153 1 PMID:16504332 -3.4.21.91 t-butyloxycarbonyl-glycyl-l-lysyl-l-arginine-4-methylcoumaryl-7-amide dengue virus type 3 0.007 0.007 1 PMID:16504332 -3.4.21.91 t-butyloxycarbonyl-glycyl-l-lysyl-l-arginine-4-methylcoumaryl-7-amide st. louis encephalitis virus 0.083 0.083 1 PMID:16504332 -3.4.21.91 t-butyloxycarbonyl-glycyl-l-lysyl-l-arginine-4-methylcoumaryl-7-amide yellow fever virus 0.006 0.006 1 PMID:16504332 -3.4.21.91 t-butyloxycarbonyl-glycyl-l-lysyl-l-arginine-4-methylcoumaryl-7-amide zika virus 0.088 0.088 1 PMID:16504332 -3.4.21.91 tert-butoxycarbonyl-gly-arg-arg-4-methylcoumarin 7-amide dengue virus 0.13 0.08 4 PMID:15932883 -3.4.21.91 vrgarrsgdvlwq yellow fever virus 0.041 0.041 1 PMID:21419753 -3.4.21.92 31-knotted methyltransferase ybea-ssra escherichia coli 0.383 0.383 1 PMID:30787316 -3.4.21.92 atp escherichia coli 2.17 1.67 2 PMID:7845217 -3.4.21.92 fegfp-ssra escherichia coli 0.0083 0.008 2 PMID:29472573 -3.4.21.92 glucagon escherichia coli 0.5 0.5 1 PMID:7845217 -3.4.21.92 insulin chain b escherichia coli 0.35 0.34 3 PMID:18816064 -3.4.21.92 n-succinyl-leu-tyr-7-amido-4-methylcoumarin escherichia coli 15.8 12.7 2 PMID:20637416 -3.4.21.92 n-succinyl-leu-tyr-7-amido-4-methylcoumarin staphylococcus aureus 0.093 0.093 1 PMID:21544912 -3.4.21.92 oxidized insulin b-chain escherichia coli 0.5 0.5 1 PMID:7845217 -3.4.21.92 phe-ala-pro-his-met-ala-leu-val-pro-val escherichia coli 13.3 13.3 1 PMID:7845217 -3.4.21.92 succinyl-llvy-7-amido-4-methylcoumarin plasmodium falciparum 3.6e-05 3.6e-05 1 PMID:20887733 -3.4.21.94 ac-arg-phe-ala-arg-4-methylcoumarin 7-amide mus musculus 0.6 0.6 1 PMID:9712897 -3.4.21.94 ac-arg-pro-lys-arg-4-methylcoumarin 7-amide mus musculus 99.0 99.0 1 PMID:9712897 -3.4.21.94 ac-lys-ser-lys-arg-4-methylcoumarin 7-amide mus musculus 43.8 43.8 1 PMID:9712897 -3.4.21.94 ac-orn-ser-lys-arg-4-methylcoumarin 7-amide mus musculus 39.6 39.6 1 PMID:9712897 -3.4.21.94 boc-gly-arg-arg-4-methylcoumarin 7-amide mus musculus 1.8 1.8 1 PMID:9712897 -3.4.21.94 boc-gly-lys-arg-4-methylcoumarin 7-amide mus musculus 1.2 1.2 1 PMID:9712897 -3.4.21.94 cbz-arg-ser-lys-arg-4-methylcoumarin 7-amide mus musculus 34.2 34.2 1 PMID:9712897 -3.4.21.94 pglu-arg-thr-lys-arg-4-methylcoumarin 7-amide mus musculus 34.2 34.2 1 PMID:9712897 -3.4.21.97 4-(4'-dimethylaminophenazo)benzoic acid-rgvvnas-2-aminobutanoyl-rln-5-[(2'-aminoethyl)-amino]-naphthalene-1-sulfonic acid human betaherpesvirus 5 0.0133 0.0133 1 PMID:8648756 -3.4.21.97 4-(4'-dimethylaminophenazo)benzoic acid-rgvvnas-2-aminobutanoyl-rln-5-[(2'-aminoethyl)-amino]-naphthalene-1-sulfonic acid human betaherpesvirus 6 0.00833 0.00833 1 PMID:8648756 -3.4.21.97 4-(4'-dimethylaminophenylazo)benzoyl-arg-gly-val-val-asn-ala-ser-ser-arg-leu-ala-5-((2'-aminoethyl)amino)-naphthalene-1-sulfonic acid human betaherpesvirus 5 0.046 0.0405 2 PMID:15325287 -3.4.21.97 abz-gvvnassrlay(no2)g human betaherpesvirus 5 0.583 0.475 2 PMID:8611517 -3.4.21.97 acetyl-cys-tert-butylglycine-tert-butylglycine-asn(me)2-ala-7-amido-4-methylcoumarin human betaherpesvirus 5 0.16 0.16 1 PMID:14717585 -3.4.21.97 gvvnascrla human betaherpesvirus 5 0.206 0.206 1 PMID:8676515 -3.4.21.97 rgvvnassrlak human betaherpesvirus 5 0.308 0.29400000000000004 2 PMID:9882568 -3.4.21.97 succinyl-lvnas-2-aminobutyryl-arg-nh2 human betaherpesvirus 5 0.133 0.133 1 PMID:8648756 -3.4.21.97 succinyl-lvnas-2-aminobutyryl-ept-nh2 human betaherpesvirus 5 0.0833 0.0833 1 PMID:8648756 -3.4.21.97 succinyl-lvnas-2-aminobutyryl-ept-nh2 human betaherpesvirus 6 0.7 0.7 1 PMID:8648756 -3.4.21.97 succinyl-rrilnaslape-nh2 human betaherpesvirus 5 0.1 0.1 1 PMID:8648756 -3.4.21.97 succinyl-rrilnaslape-nh2 human betaherpesvirus 6 0.217 0.217 1 PMID:8648756 -3.4.21.97 succinyl-rryikaseppv-nh2 human betaherpesvirus 5 0.0333 0.0333 1 PMID:8648756 -3.4.21.97 succinyl-rryikaseppv-nh2 human betaherpesvirus 6 0.0833 0.0833 1 PMID:8648756 -3.4.21.97 succinyl-syvkasvs-nh2 human betaherpesvirus 5 0.0167 0.0167 1 PMID:8648756 -3.4.21.97 succinyl-syvkasvs-nh2 human betaherpesvirus 6 0.217 0.217 1 PMID:8648756 -3.4.21.97 succinyl-vvnas-2-aminobutyryl-r-nh2 human betaherpesvirus 6 0.05 0.05 1 PMID:8648756 -3.4.21.97 succinyl-yvkasepla-nh2 human betaherpesvirus 5 0.0333 0.0333 1 PMID:8648756 -3.4.21.97 succinyl-yvkasepla-nh2 human betaherpesvirus 6 0.167 0.167 1 PMID:8648756 -3.4.21.97 syvkasvspe human betaherpesvirus 5 0.075 0.0675 2 PMID:9882568 -3.4.21.98 2-naph-3pya-lys-arg-p-nitroanilide west nile virus 0.96 0.96 1 PMID:17052977 -3.4.21.98 2-naph-cit-lys-arg-p-nitroanilide west nile virus 0.32 0.32 1 PMID:17052977 -3.4.21.98 2-naph-cit-orn-arg-p-nitroanilide west nile virus 0.57 0.57 1 PMID:17052977 -3.4.21.98 2-naph-harg-lys-arg-p-nitroanilide west nile virus 0.11 0.11 1 PMID:17052977 -3.4.21.98 2-naph-lys-aclys-arg-p-nitroanilide west nile virus 0.3 0.3 1 PMID:17052977 -3.4.21.98 2-naph-lys-arg-arg-p-nitroanilide west nile virus 0.89 0.89 1 PMID:17052977 -3.4.21.98 2-naph-lys-cit-arg-p-nitroanilide west nile virus 0.43 0.43 1 PMID:17052977 -3.4.21.98 2-naph-lys-harg-arg-p-nitroanilide west nile virus 0.59 0.59 1 PMID:17052977 -3.4.21.98 2-naph-lys-lys-arg-p-nitroanilide west nile virus 1.08 1.08 1 PMID:17052977 -3.4.21.98 2-naph-lys-orn-arg-p-nitroanilide west nile virus 1.58 1.58 1 PMID:17052977 -3.4.21.98 2-naph-orn-lys-arg-p-nitroanilide west nile virus 0.98 0.98 1 PMID:17052977 -3.4.21.98 2-naph-orn-orn-arg-p-nitroanilide west nile virus 0.27 0.27 1 PMID:17052977 -3.4.21.98 7-methoxycoumarin-4-acetyl-demeecashlpyk-(epsilon-nhcoch3) hepacivirus hominis 0.15 0.078 2 PMID:10425166 -3.4.21.98 7-methoxycoumarin-4-acetyl-edastpcsgsn-(4-nitro)phe hepacivirus hominis 0.227 0.227 1 PMID:10425166 -3.4.21.98 9-fluorenylmethyloxycarbonyl-yqefdemeecashlpyieqg hepacivirus hominis 0.00833 0.00833 1 PMID:8794305 -3.4.21.98 ac-aib-lys-lys-arg-p-nitroanilide west nile virus 1.6 1.6 1 PMID:17052977 -3.4.21.98 ac-aoc-lys-lys-arg-p-nitroanilide west nile virus 2.51 2.51 1 PMID:17052977 -3.4.21.98 ac-asp-glu-lys(tamra)-glu-glu-abupsi[coo]-ala-ser-lys(qsy-7)-amide hepacivirus hominis 7.2 1.1 4 PMID:17644059 -3.4.21.98 ac-cha-lys-lys-arg-p-nitroanilide west nile virus 2.28 2.28 1 PMID:17052977 -3.4.21.98 ac-chg-lys-lys-arg-p-nitroanilide west nile virus 1.78 1.78 1 PMID:17052977 -3.4.21.98 ac-deemecashlpyk-nh2 hepacivirus hominis 0.03 0.0253 7 PMID:9930676 -3.4.21.98 ac-dpnrkr-4-nitroanilide west nile virus 1.3 1.3 1 PMID:15322074 -3.4.21.98 ac-dtedvvp(nva)-o-4-phenylazophenyl ester hepacivirus hominis 0.57 0.43 3 PMID:16445277 -3.4.21.98 ac-emeecashlp hepacivirus hominis 0.005 0.005 1 PMID:8794305 -3.4.21.98 ac-fasgkr-4-nitroanilide west nile virus 1.9 1.9 1 PMID:15322074 -3.4.21.98 ac-kpglkr-4-nitroanilide west nile virus 6.08 1.5 3 PMID:15322074;PMID:15494419 -3.4.21.98 ac-l-asp-l-glu-l-asp-(edans)-l-glu-l-glu-alpha-aminobutyric acid-psi[coo]-l-ala-l-ser-l-lys-(dabcyl)-nh2 hepacivirus hominis 1.0 1.0 1 PMID:16087668 -3.4.21.98 ac-leu-3pya-lys-arg-p-nitroanilide west nile virus 0.5 0.5 1 PMID:17052977 -3.4.21.98 ac-leu-4pya-lys-arg-p-nitroanilide west nile virus 0.9 0.9 1 PMID:17052977 -3.4.21.98 ac-leu-aphe-lys-arg-p-nitroanilide west nile virus 0.75 0.75 1 PMID:17052977 -3.4.21.98 ac-leu-cit-lys-arg-p-nitroanilide west nile virus 1.44 1.44 1 PMID:17052977 -3.4.21.98 ac-leu-gln-tyr-thr-lys-arg-p-nitroanilide west nile virus 0.266 0.266 1 PMID:17052977 -3.4.21.98 ac-leu-harg-lys-arg-p-nitroanilide west nile virus 118.0 118.0 1 PMID:17052977 -3.4.21.98 ac-leu-lys-lys-arg-p-nitroanilide west nile virus 1.64 1.64 1 PMID:17052977 -3.4.21.98 ac-leu-nphe-lys-arg-p-nitroanilide west nile virus 0.72 0.72 1 PMID:17052977 -3.4.21.98 ac-leu-orn-lys-arg-p-nitroanilide west nile virus 1.79 1.79 1 PMID:17052977 -3.4.21.98 ac-lqytkr-4-nitroanilide west nile virus 1.1 1.1 1 PMID:15322074 -3.4.21.98 ac-nle-lys-lys-arg-p-nitroanilide west nile virus 2.35 2.35 1 PMID:17052977 -3.4.21.98 ac-nva-lys-lys-arg-p-nitroanilide west nile virus 2.36 2.36 1 PMID:17052977 -3.4.21.98 ac-tbg-lys-lys-arg-p-nitroanilide west nile virus 1.74 1.74 1 PMID:17052977 -3.4.21.98 ac-yqefdemeecas hepacivirus hominis 0.005 0.005 1 PMID:8794305 -3.4.21.98 ac-yqefdemeecash hepacivirus hominis 0.00333 0.00333 1 PMID:8794305 -3.4.21.98 ac-yqefdemeecashl hepacivirus hominis 0.00667 0.00667 1 PMID:8794305 -3.4.21.98 ac-yqefdemeecashlp hepacivirus hominis 0.00667 0.00667 1 PMID:8794305 -3.4.21.98 acetyl-demeecashlpyk-(epsilon-nhcoch3) hepacivirus hominis 0.143 0.143 1 PMID:10425166 -3.4.21.98 anthraniloyl-ddivp-abu[c(o)-o] amy(3-no2)-tw-oh hepacivirus hominis 1.7 0.83 5 PMID:19944069 -3.4.21.98 anthranilyl-ddivpabu[c(o)-o]amy(3-no2)tw-oh hepacivirus hominis 2.5 2.5 1 PMID:19119853 -3.4.21.98 boc-gly-arg-arg-amc yellow fever virus 0.034 0.034 1 PMID:17622626 -3.4.21.98 boc-rvrr-7-amido-4-methylcoumarin west nile virus 0.073 0.073 1 PMID:16229682 -3.4.21.98 bz-norleucine-lysine-arginine-arginine-amc yellow fever virus 0.111 0.111 1 PMID:17622626 -3.4.21.98 demeecsqhlpyi hepacivirus hominis 0.243 0.1465 2 PMID:9235976 -3.4.21.98 dtedvvccsmsytwtgk hepacivirus hominis 0.317 0.167 3 PMID:9792101 -3.4.21.98 eagddivpcsmsytwtga-oh hepacivirus hominis 0.7 0.7 1 PMID:11170379 -3.4.21.98 eagdnivpcsmsytwtga-oh hepacivirus hominis 0.8 0.8 1 PMID:11170379 -3.4.21.98 eagndivpcsmsytwtga-oh hepacivirus hominis 0.7 0.7 1 PMID:11170379 -3.4.21.98 eagnnivpcsmsytwtga-oh hepacivirus hominis 6.08 3.375 2 PMID:11170379 -3.4.21.98 edvv-4-aminobutyryl-csmsy hepacivirus hominis 0.6 0.39 2 PMID:9235976 -3.4.21.98 glu-asp-val-val-4-aminobutyryl-cys-p-nitroanilide hepacivirus hominis 0.2 0.10600000000000001 2 PMID:9235976 -3.4.21.98 o-aminobenzoyl (abz)-l-asp-l-asp-l-ile-l-val-l-pro-l-cys-l-ser-l-met-l-ser-l-tyr(3-no2)-l-thr-nh2 hepacivirus hominis 0.0065 0.0065 1 PMID:15850392 -3.4.21.98 pyr-rtkr-7-amido-4-methylcoumarin west nile virus 43.0 43.0 1 PMID:16229682 -3.4.21.98 z-rr-7-amido-4-methylcoumarin west nile virus 0.062 0.062 1 PMID:16229682 -3.4.22.1 abz-frf(no2)a nicotiana benthamiana 2.9 2.9 1 PMID:26166069 -3.4.22.1 abz-givrak(dnp)-oh homo sapiens 43.0 43.0 1 PMID:15556563 -3.4.22.1 abz-givrak-dnp nicotiana benthamiana 0.1 0.1 1 PMID:26166069 -3.4.22.1 arg-4-methylcoumaryl-7-amide homo sapiens 0.004 0.004 1 * -3.4.22.1 azocasein oryctolagus cuniculus 1e-09 1e-09 1 PMID:3223923 -3.4.22.1 benzoyl-dl-arg-beta-naphthylamide bos taurus 0.075 0.075 1 PMID:510307 -3.4.22.1 benzoyl-dl-arg-p-nitroanilide gallus gallus 83.0 83.0 1 PMID:2907328 -3.4.22.1 benzoyl-phe-val-arg-4-methylcoumaryl-7-amide oryctolagus cuniculus 8.12 8.12 1 PMID:3223923 -3.4.22.1 benzyloxycarbonyl-ala-arg-arg-4-methoxy-beta-naphthylamide homo sapiens 0.125 0.125 1 * -3.4.22.1 benzyloxycarbonyl-ala-arg-arg-4-methoxy-beta-naphthylamide sus scrofa 87.0 87.0 1 PMID:108278 -3.4.22.1 benzyloxycarbonyl-arg-arg-4-methoxy-beta-naphthylamide homo sapiens 0.139 0.139 1 * -3.4.22.1 benzyloxycarbonyl-arg-arg-4-methylcoumaryl-7-amide bos taurus 75.0 75.0 1 PMID:2223009 -3.4.22.1 benzyloxycarbonyl-arg-arg-4-methylcoumaryl-7-amide cyprinus carpio 8.97 8.97 1 * -3.4.22.1 benzyloxycarbonyl-arg-arg-4-methylcoumaryl-7-amide homo sapiens 158.0 43.0 3 PMID:2844149;PMID:9761485 -3.4.22.1 benzyloxycarbonyl-arg-arg-4-methylcoumaryl-7-amide oryctolagus cuniculus 3.45 3.45 1 PMID:3223923 -3.4.22.1 benzyloxycarbonyl-arg-arg-4-methylcoumaryl-7-amide schistosoma mansoni 12.2 12.2 1 PMID:8719966 -3.4.22.1 benzyloxycarbonyl-arg-arg-7-amido-4-methylcoumarin nicotiana benthamiana 11.0 11.0 1 PMID:26166069 -3.4.22.1 benzyloxycarbonyl-l-leucyl-l-arginine-4-methylcoumaryl-7-amide naegleria fowleri 0.512 0.4195 2 PMID:24832815 -3.4.22.1 benzyloxycarbonyl-l-phenylalaninyl-l-arginine 4-methylcoumaryl-7-amide naegleria fowleri 0.476 0.397 2 PMID:24832815 -3.4.22.1 benzyloxycarbonyl-phe-arg-4-methylcoumaryl-7-amide cyprinus carpio 34.0 34.0 1 * -3.4.22.1 benzyloxycarbonyl-phe-arg-4-methylcoumaryl-7-amide gallus gallus 2.4 2.4 1 PMID:2907328 -3.4.22.1 benzyloxycarbonyl-phe-arg-4-methylcoumaryl-7-amide homo sapiens 364.0 182.2225 2 PMID:2844149 -3.4.22.1 benzyloxycarbonyl-phe-arg-4-methylcoumaryl-7-amide oryctolagus cuniculus 7.67 7.67 1 PMID:3223923 -3.4.22.1 benzyloxycarbonyl-phe-arg-4-methylcoumaryl-7-amide schistosoma mansoni 49.5 49.5 1 PMID:8719966 -3.4.22.1 benzyloxycarbonyl-phe-arg-4-methylcoumaryl-7-amide sus scrofa 71.0 71.0 1 PMID:7334002 -3.4.22.1 benzyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin nicotiana benthamiana 4.7 4.7 1 PMID:26166069 -3.4.22.1 benzyloxycarbonyl-val-lys-lys-arg-4-methoxy-beta-naphthylamide homo sapiens 0.325 0.325 1 * -3.4.22.1 benzyloxycarbonyl-val-lys-lys-arg-4-methoxy-beta-naphthylamide sus scrofa 68.0 68.0 1 PMID:108278 -3.4.22.1 boc-asp-pro-arg-4-methyl-7-amidocoumarin homo sapiens 0.28 0.28 1 PMID:19401154 -3.4.22.1 boc-asp-pro-arg-4-methylcoumarin 7-amide fasciola hepatica 0.69 0.69 1 PMID:19401154 -3.4.22.1 boc-val-leu-lys-4-methyl-7-amidocoumarin homo sapiens 3.38 3.38 1 PMID:19401154 -3.4.22.1 boc-val-pro-arg-4-methylcoumarin 7-amide fasciola hepatica 0.72 0.72 1 PMID:19401154 -3.4.22.1 collagen oryctolagus cuniculus 0.000625 0.000625 1 PMID:3223923 -3.4.22.1 d-val-leu-arg-4-methylcoumarin 7-amide fasciola hepatica 0.14 0.14 1 PMID:19401154 -3.4.22.1 gelatin oryctolagus cuniculus 8.17e-09 8.17e-09 1 PMID:3223923 -3.4.22.1 n,n'-diboc-dityrosine-gly-(isoniazid)2 homo sapiens 0.011 0.011 1 PMID:23348078 -3.4.22.1 n,n'-diboc-dityrosine-lys-(isoniazid)2 homo sapiens 0.036 0.036 1 PMID:23348078 -3.4.22.1 n-[(benzyloxy)carbonyl]-l-alanyl-n-[4-([[(5-[[5-(dimethylamino)naphthalene-1-sulfonyl]amino]pentyl)carbamoyl]oxy]methyl)phenyl]-n6-(2,4-dinitrophenyl)-l-lysinamide homo sapiens 2.4 2.4 1 PMID:31493706 -3.4.22.1 n-benzyloxycarbonyl-arg-arg-4-methyl-7-amidocoumarin homo sapiens 1.09 1.09 1 PMID:19401154 -3.4.22.1 n-benzyloxycarbonyl-arg-arg-4-methylcoumarin 7-amide fasciola hepatica 0.13 0.13 1 PMID:19401154 -3.4.22.1 n-benzyloxycarbonyl-phe-arg-4-methyl-7-amidocoumarin homo sapiens 1.71 1.71 1 PMID:19401154 -3.4.22.1 n-benzyloxycarbonyl-phe-arg-4-methylcoumarin 7-amide fasciola hepatica 0.19 0.19 1 PMID:19401154 -3.4.22.1 n-benzyloxycarbonyl-val-ile-arg-4-methylcoumarin 7-amide fasciola hepatica 0.51 0.51 1 PMID:19401154 -3.4.22.1 nalpha-benzoyl-arg-arg-7-amido-4-methylcoumarin homo sapiens 67.0 67.0 1 PMID:19040356 -3.4.22.1 nalpha-benzoyl-arg-arg-7-amido-4-methylcoumarin mus musculus 34.0 34.0 1 PMID:19040356 -3.4.22.1 nalpha-benzoyl-phe-arg-7-amido-4-methylcoumarin homo sapiens 115.0 115.0 1 PMID:19040356 -3.4.22.1 nalpha-benzoyl-phe-arg-7-amido-4-methylcoumarin mus musculus 86.0 86.0 1 PMID:19040356 -3.4.22.1 nalpha-carbobenzoxy-l-arg-l-arg-7-amido-4-trifluoromethylcoumarin meretrix meretrix 277.6 277.6 1 PMID:20853148 -3.4.22.1 tos-gly-pro-arg-4-methyl-7-amidocoumarin homo sapiens 2.26 2.26 1 PMID:19401154 -3.4.22.1 tos-gly-pro-arg-4-methylcoumarin 7-amide fasciola hepatica 0.13 0.13 1 PMID:19401154 -3.4.22.10 acetyl-ala-ile-arg-7-amino-4-methylcoumarin streptococcus pyogenes 0.69 0.69 1 PMID:22645124 -3.4.22.10 benzyloxycarbonyl-glu-phe streptococcus sp. 2.3 2.3 1 * -3.4.22.10 benzyloxycarbonyl-lys-p-nitrophenyl ester streptococcus sp. 142.0 89.8 3 * -3.4.22.10 benzyloxycarbonyl-lys-phe streptococcus sp. 1.09 1.09 1 * -3.4.22.10 benzyloxycarbonyl-val-arg-4-methylcoumarinyl-7-amide streptococcus pyogenes 0.042 0.042 1 PMID:10429198 -3.4.22.10 cinnamoyl-gly-p-nitrophenyl ester streptococcus sp. 1.52 1.52 1 PMID:4683008 -3.4.22.10 n-benzoyl-gly-p-nitrophenyl ester streptococcus sp. 0.21 0.21 1 PMID:4683008 -3.4.22.10 n-benzyloxycarbonyl-ala-p-nitrophenyl ester streptococcus sp. 118.0 118.0 1 PMID:4683008 -3.4.22.10 n-benzyloxycarbonyl-gly-p-nitrophenyl ester streptococcus sp. 9.4 9.4 1 PMID:4683008 -3.4.22.10 nalpha-benzyloxycarbonyl-lys-p-nitrophenyl ester streptococcus sp. 190.0 180.0 4 PMID:4683009 -3.4.22.10 nalpha-benzyloxycarbonyl-lys-phe streptococcus sp. 5.05 5.05 1 * -3.4.22.10 nalpha-benzyloxycarbonyl-lys-phenyl ester streptococcus sp. 174.0 174.0 1 PMID:4683009 -3.4.22.10 nalpha-benzyloxycarbonyl-nepsilon-t-butyloxycarbonyl-lys-phe streptococcus sp. 8.6 8.6 1 * -3.4.22.10 p-nitrobenzyloxycarbonyl-gly-p-nitrophenyl ester streptococcus sp. 1.15 1.15 1 PMID:4683008 -3.4.22.10 t-butyloxycarbonyl-gly-p-nitrophenyl ester streptococcus sp. 0.147 0.147 1 PMID:4683008 -3.4.22.10 tert-butyloxycarbonyl-ala-p-nitrophenyl ester streptococcus sp. 4.31 4.31 1 PMID:4683008 -3.4.22.14 acetyl-lys methyl ester actinidia chinensis 0.7 0.7 1 PMID:7002215 -3.4.22.14 benzoyl-arg 4-nitroanilide actinidia chinensis 0.029 0.029 1 PMID:7002215 -3.4.22.14 benzoyl-arg ethyl ester actinidia chinensis 4.5 4.5 1 PMID:7002215 -3.4.22.14 benzoyl-gly p-nitrophenyl ester actinidia chinensis 5.8 5.8 1 PMID:7002215 -3.4.22.14 benzoyl-l-arg ethyl ester actinidia chinensis 2.6 2.6 1 PMID:5506167 -3.4.22.14 benzyloxycarbonyl 4-nitrophenyl ester actinidia chinensis 3.4 3.4 1 PMID:7002215 -3.4.22.14 benzyloxycarbonyl-lys methyl ester actinidia chinensis 6.0 6.0 1 PMID:7002215 -3.4.22.14 benzyloxycarbonyl-lys p-nitrophenyl ester actinidia chinensis 29.0 29.0 1 PMID:7002215 -3.4.22.14 casein actinidia deliciosa 29.2 24.97 2 PMID:25450831 -3.4.22.14 milk protein concentrate actinidia deliciosa 0.0065 0.0065 1 PMID:38231667 -3.4.22.14 n-alpha-benzyloxycarbonyl-l-lysine 4-nitrophenyl ester actinidia deliciosa 42.8 42.8 1 PMID:24604128 -3.4.22.14 nalpha-benzyloxycarbonyl-l-lys p-nitrophenyl ester actinidia chinensis 33.0 33.0 1 PMID:7034724 -3.4.22.14 whey protein isolate actinidia deliciosa 0.0165 0.0165 1 PMID:38231667 -3.4.22.15 2-aminobenzoyl-ala-leu-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 5.3 5.3 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-arg-leu-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.8 3.8 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-asn-leu-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.5 3.5 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-gln-leu-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.8 3.8 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-glu-glu-epsilon-amino-caproic acid-glu-leu-lys-leu-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.4 0.4 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-glu-leu-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 4.0 4.0 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-glu-leu-lys-leu-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.2 1.2 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-gly-leu-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.1 0.1 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-his-leu-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 5.9 5.9 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-ile-leu-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.3 2.3 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-arg-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.2 3.2 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-asn-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.4 0.4 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-asp-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.4 0.4 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-gln-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.7 1.7 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-glu-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.4 0.4 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-gly-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.5 0.5 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-his-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.3 1.3 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-ile-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.3 2.3 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-ala-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.1 1.1 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-arg-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.7 3.7 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-asn-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 6.3 6.3 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-gln-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 5.8 5.8 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-glu-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 4.9 4.9 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-gly-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.4 3.4 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-his-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 7.3 7.3 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-ile-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.9 3.9 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-ser-ala-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 4.1 4.1 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-ser-arg-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.6 3.6 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-ser-asn-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.3 2.3 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-ser-gln-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 4.2 4.2 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-ser-glu-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 4.1 4.1 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-ser-gly-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 4.8 4.8 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-ser-his-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.7 3.7 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-ser-ile-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.4 2.4 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-ser-pro-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 6.0 6.0 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 4.6 4.6 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-ser-val-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.2 3.2 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-arg-val-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 5.5 5.5 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-asn-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.1 1.1 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-asp-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.2 0.2 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-gln-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.9 0.9 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-glu-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.6 2.6 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-gly-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.4 0.4 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-his-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.3 1.3 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-ile-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.4 0.4 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-lys-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.1 3.1 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-met-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.4 0.4 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-pro-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.1 0.1 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-ser-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.5 1.5 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-thr-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.3 1.3 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-leu-val-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.5 0.5 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-lys-epsilon-amino-caproic acid-glu-leu-lys-leu-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.9 1.9 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-met-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 4.0 4.0 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-phe-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 13.5 13.5 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-pro-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.2 1.2 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-ser-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.9 1.9 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-thr-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.4 0.4 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-trp-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.9 1.9 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-tyr-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 7.8 7.8 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-lys-val-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 6.4 6.4 1 PMID:15369827 -3.4.22.15 2-aminobenzoyl-val-leu-arg-ser-ser-lys-gln-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.1 2.1 1 PMID:15369827 -3.4.22.15 abz-3-biphenyl-l-ala-arg-ala-ala-tyr(3-no2)-nh2 homo sapiens 17.4 17.4 1 PMID:25151941 -3.4.22.15 abz-3-biphenyl-l-ala-arg-ala-gln-tyr(3-no2)-nh2 homo sapiens 27.0 27.0 1 PMID:25151941 -3.4.22.15 abz-3-biphenyl-l-ala-arg-ala-ser-tyr(3-no2)-nh2 homo sapiens 5.01 5.01 1 PMID:25151941 -3.4.22.15 abz-pr-acetyl-k-qlatkaarksak-dnp homo sapiens 0.49 0.49 1 PMID:21326229 -3.4.22.15 abz-prkqlat-acetyl-k-aarksak-dnp homo sapiens 0.37 0.37 1 PMID:21326229 -3.4.22.15 abz-prkqlatkaar-dimethyl-k-sak-dnp homo sapiens 0.51 0.51 1 PMID:21326229 -3.4.22.15 abz-prkqlatkaarksak-dnp homo sapiens 0.46 0.46 1 PMID:21326229 -3.4.22.15 benzyloxycarbonyl-gly-pro-arg-7-amido-4-methylcoumarin homo sapiens 0.01 0.01 1 PMID:17384231 -3.4.22.15 benzyloxycarbonyl-l-phe-l-arg-7-amido-4-methylcoumarin homo sapiens 0.285 0.285 1 PMID:38271604 -3.4.22.15 benzyloxycarbonyl-l-phe-l-arg-7-amido-4-methylcoumarin takifugu rubripes 0.0332 0.0332 1 * -3.4.22.15 benzyloxycarbonyl-leu-arg-7-amido-4-methylcoumarin homo sapiens 17.6 17.6 1 PMID:17384231 -3.4.22.15 benzyloxycarbonyl-lys-p-nitrophenyl ester rattus norvegicus 19.8 19.8 1 * -3.4.22.15 benzyloxycarbonyl-phe-arg-4-methylcoumarin 7-amide cyprinus carpio 9.5 9.5 1 PMID:9467867 -3.4.22.15 benzyloxycarbonyl-phe-arg-4-methylcoumarin 7-amide gallus gallus 30.0 30.0 1 PMID:2435279;PMID:3676277 -3.4.22.15 benzyloxycarbonyl-phe-arg-4-methylcoumarin 7-amide homo sapiens 50.0 25.8 5 PMID:2435279;PMID:2844149;PMID:8941355 -3.4.22.15 benzyloxycarbonyl-phe-arg-4-methylcoumarin 7-amide oncorhynchus keta 15.8 15.8 1 PMID:2361361 -3.4.22.15 benzyloxycarbonyl-phe-arg-4-methylcoumarin 7-amide oryctolagus cuniculus 20.0 20.0 1 PMID:2435279;PMID:6421281 -3.4.22.15 benzyloxycarbonyl-phe-arg-4-methylcoumarin 7-amide ovis aries 30.0 30.0 1 PMID:2435279;PMID:3676277 -3.4.22.15 benzyloxycarbonyl-phe-arg-4-methylcoumarin 7-amide rattus norvegicus 26.0 15.765 2 PMID:2435279;PMID:3688881 -3.4.22.15 benzyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin agama stellio stellio 6.2 6.2 1 PMID:11002190 -3.4.22.15 benzyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin homo sapiens 46.0 25.7 2 PMID:17384231;PMID:18221013 -3.4.22.15 benzyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin hypophthalmichthys molitrix 3.7 3.7 1 PMID:17147449 -3.4.22.15 efl-4-nitroanilide homo sapiens 0.6685 0.6685 1 PMID:33825882 -3.4.22.15 l-phe-l-arg-7-amido-4-methylcoumarin trypanosoma brucei 1.01 0.485 6 PMID:22234330 -3.4.22.15 l-val-l-leu-l-arg-7-amido-4-methylcoumarin trypanosoma brucei 1.07 0.98 2 PMID:22234330 -3.4.22.15 leu-trp-met-arg-phe-ala rattus norvegicus 26.6 26.6 1 PMID:3688881 -3.4.22.15 leucine enkephalin rattus norvegicus 33.9 33.9 1 PMID:3688881 -3.4.22.15 methionine enkephalin-arg-phe rattus norvegicus 43.2 43.2 1 PMID:3688881 -3.4.22.15 n-[(benzyloxy)carbonyl]-l-alanyl-n-[4-([[(5-[[5-(dimethylamino)naphthalene-1-sulfonyl]amino]pentyl)carbamoyl]oxy]methyl)phenyl]-n6-(2,4-dinitrophenyl)-l-lysinamide homo sapiens 0.16 0.16 1 PMID:31493706 -3.4.22.15 n-carbobenzoxy-l-phenylalanine-l-arginine 7-amido-4-methylcoumarin apostichopus japonicus 12.8 12.8 1 PMID:18540081 -3.4.22.15 pro-phe-arg-4-methylcoumarin 7-amide cyprinus carpio 1.52 1.52 1 PMID:9467867 -3.4.22.15 tert-butyloxycarbonyl-val-leu-lys-4-methylcoumarin 7-amide cyprinus carpio 1.67 1.67 1 PMID:9467867 -3.4.22.15 vlk-4-nitroanilide homo sapiens 1.873 1.873 1 PMID:33825882 -3.4.22.16 ala-4-methylcoumaryl-7-amide cyprinus carpio 1.87 1.87 1 PMID:9206588 -3.4.22.16 arg-2-naphthylamide bos taurus 115.0 115.0 1 PMID:8713750 -3.4.22.16 arg-2-naphthylamide homo sapiens 1.82 1.82 1 PMID:7043200 -3.4.22.16 arg-4-methylcoumaryl-7-amide cyprinus carpio 2.2 2.2 1 PMID:9206588 -3.4.22.16 arg-4-methylcoumaryl-7-amide homo sapiens 2.53 2.53 1 PMID:7043200 -3.4.22.16 arg-4-methylcoumaryl-7-amide rattus norvegicus 8.13 8.13 1 PMID:1483460 -3.4.22.16 benzoyl-arg-2-naphthylamide homo sapiens 1.82 1.82 1 PMID:7043200 -3.4.22.16 benzoyl-arg-4-methylcoumaryl-7-amide rattus norvegicus 0.63 0.63 1 PMID:1483460 -3.4.22.16 benzyloxycarbonyl-pro-ala-ala-ala-pro rattus norvegicus 5.3 5.3 1 PMID:3663163 -3.4.22.16 benzyloxycarbonyl-pro-ala-ala-ala-pro-nh2 rattus norvegicus 7.7 7.7 1 PMID:3663163 -3.4.22.16 citrulline-4-methylcoumaryl-7-amide rattus norvegicus 3.1 3.1 1 PMID:1483460 -3.4.22.16 leu-2-naphthylamide bos taurus 122.0 122.0 1 PMID:8713750 -3.4.22.16 leu-4-methylcoumaryl-7-amide cyprinus carpio 1.1 1.1 1 PMID:9206588 -3.4.22.16 lys-4-methylcoumaryl-7-amide cyprinus carpio 4.13 4.13 1 PMID:9206588 -3.4.22.16 met-2-naphthylamide bos taurus 219.0 219.0 1 PMID:8713750 -3.4.22.16 succinyl-ala-ala-4-nitroanilide rattus norvegicus 0.07 0.07 1 PMID:3663163 -3.4.22.16 succinyl-ala-ala-ala-4-nitroanilide rattus norvegicus 0.3 0.3 1 PMID:3663163 -3.4.22.16 succinyl-ala-ala-ala-ala-4-nitroanilide rattus norvegicus 0.9 0.9 1 PMID:3663163 -3.4.22.16 succinyl-ala-ala-ala-ala-ala-4-nitroanilide rattus norvegicus 0.8 0.8 1 PMID:3663163 -3.4.22.16 succinyl-ala-ala-pro-4-nitroanilide rattus norvegicus 0.004 0.004 1 PMID:3663163 -3.4.22.16 succinyl-pro-ala-ala-4-nitroanilide rattus norvegicus 0.15 0.15 1 PMID:3663163 -3.4.22.2 benzoyl-thiocarbamic acid carica papaya 3340.0 3340.0 1 PMID:4074728 -3.4.22.2 benzoyl-thiocarbamic acid ethyl ester carica papaya 3.4 3.4 1 PMID:4074728 -3.4.22.2 benzoyl-thiocarbamic acid methyl ester carica papaya 0.064 0.064 1 PMID:4074728 -3.4.22.2 benzyl-phe-val-arg-4-nitroanilide carica papaya 309.0 216.0 6 * -3.4.22.2 benzyloxycarbonyl-arg-arg 4-methylcoumarin-7-amide carica papaya 1.18 1.18 1 PMID:1892810 -3.4.22.2 benzyloxycarbonyl-l-phe-l-arg-7-amido-4-methylcoumarin carica papaya 52.0 51.5 2 PMID:2397208 -3.4.22.2 benzyloxycarbonyl-phe-arg 4-methylcoumarin-7-amide carica papaya 41.6 41.6 1 PMID:1892810 -3.4.22.2 boc-l-his carica papaya 0.00078 0.00078 1 PMID:36051592 -3.4.22.2 casein carica papaya 1.79 0.0132 12 PMID:19280124;PMID:19479190;PMID:24658998;PMID:25661879;PMID:28223134 -3.4.22.2 dabcyl-lys-phe-gly-gly-ala-ala-edans carica papaya 6.86 1.8014999999999999 6 PMID:11995992;PMID:11996007 -3.4.22.2 methyl red-abu-ala-pro-val-lys-lys(n5-(5-carboxyfluorescein))-nh2 carica papaya 1773.0 1124.0 2 PMID:18814838 -3.4.22.2 methyl red-abu-ser-ala-pro-val-lys-ala-lys(n6-(5-carboxyfluorescein))-nh2 carica papaya 1503.0 873.0 2 PMID:18814838 -3.4.22.2 milk protein concentrate carica papaya 0.0053 0.0053 1 PMID:38231667 -3.4.22.2 n-alpha-benzyloxycarbonyl-l-lysine 4-nitrophenyl ester carica papaya 35.6 35.6 1 PMID:24604128 -3.4.22.2 n-benzoyl-gly methyl ester carica papaya 3.48 3.48 1 PMID:4074728 -3.4.22.2 nalpha-benzoyl-l-arg ethyl ester carica papaya 28.5 24.0 3 PMID:4372948;PMID:4733241;PMID:5489841 -3.4.22.2 ubiquitin-7-amido-4-trifluoromethylcoumarin alphacoronavirus 0.96 0.875 2 PMID:22391227 -3.4.22.2 whey protein isolate carica papaya 0.0046 0.0046 1 PMID:38231667 -3.4.22.25 tert-butyloxycarbonyl-ala-ala-ala 4-methylcoumarin 7-amide carica papaya 0.08 0.08 1 PMID:2404797 -3.4.22.25 tert-butyloxycarbonyl-ala-ala-gly 4-methylcoumarin 7-amide carica papaya 5.0 5.0 1 PMID:2404797 -3.4.22.25 tert-butyloxycarbonyl-ala-ala-gly 4-nitroanilide carica papaya 22.0 22.0 1 PMID:2404797 -3.4.22.26 d-ala-pro-arg-4-nitroanilide homo sapiens 0.0132 0.0132 1 PMID:9259116 -3.4.22.26 d-ile-pro-arg-4-nitroanilide homo sapiens 0.0082 0.0082 1 PMID:9259116 -3.4.22.26 glu-glu-pro-arg-4-nitroanilide homo sapiens 0.0119 0.0119 1 PMID:9259116 -3.4.22.26 lpapr-7-amido-4-methylcoumarin homo sapiens 3.942 3.942 1 PMID:26341972 -3.4.22.26 n-p-tosyl-gly-pro-arg-4-nitroanilide homo sapiens 0.0073 0.0073 1 PMID:9259116 -3.4.22.26 n-p-tosyl-gly-pro-lys-4-nitroanilide homo sapiens 0.0129 0.0129 1 PMID:9259116 -3.4.22.26 pqvr-7-amido-4-methylcoumarin homo sapiens 4.578 4.578 1 PMID:26341972 -3.4.22.26 qspvr-7-amido-4-methylcoumarin homo sapiens 2.496 2.496 1 PMID:26341972 -3.4.22.26 qvr-7-amido-4-methylcoumarin homo sapiens 1.147 1.147 1 PMID:26341972 -3.4.22.26 tert-benzyloxycarbonyl-qvr-7-amido-4-methylcoumarin homo sapiens 0.989 0.989 1 PMID:26341972 -3.4.22.27 (4-methyl-7-[[(2s)-2-(4-[(1s)-1-(4-methylcyclohexyl)-1-[(thiophen-3-ylcarbonyl)amino]ethyl]-1h-1,2,3-triazol-1-yl)hexanoyl]amino]-2-oxo-2h-chromen-3-yl)acetic acid homo sapiens 0.46 0.46 1 PMID:17034136 -3.4.22.27 (7-[[(2s)-2-(4-[(1s)-1,2-dimethyl-1-[(phenylcarbonyl)amino]propyl]-1h-1,2,3-triazol-1-yl)hexanoyl]amino]-4-methyl-2-oxo-2h-chromen-3-yl)acetic acid homo sapiens 0.45 0.45 1 PMID:17034136 -3.4.22.27 (7-[[(2s)-2-(4-[(1s)-1,2-dimethyl-1-[(thiophen-3-ylcarbonyl)amino]propyl]-1h-1,2,3-triazol-1-yl)hexanoyl]amino]-4-methyl-2-oxo-2h-chromen-3-yl)acetic acid homo sapiens 0.77 0.77 1 PMID:17034136 -3.4.22.27 (7-[[(2s)-2-(4-[(1s)-1-cyclohexyl-1-[(phenylcarbonyl)amino]ethyl]-1h-1,2,3-triazol-1-yl)hexanoyl]amino]-4-methyl-2-oxo-2h-chromen-3-yl)acetic acid homo sapiens 0.2 0.2 1 PMID:17034136 -3.4.22.27 (7-[[(2s)-2-(4-[(1s)-1-cyclohexyl-1-[(thiophen-3-ylcarbonyl)amino]ethyl]-1h-1,2,3-triazol-1-yl)hexanoyl]amino]-4-methyl-2-oxo-2h-chromen-3-yl)acetic acid homo sapiens 0.22 0.22 1 PMID:17034136 -3.4.22.27 (7-methoxycoumarin-4-yl)-acetyl-grwppmglpwek(2,4-dinitrophenyl)-d-arg-nh2 homo sapiens 5.666 5.666 1 PMID:18957408 -3.4.22.27 azocasein oryctolagus cuniculus 1.1e-08 1.1e-08 1 PMID:3223923 -3.4.22.27 benzoyl-phe-val-arg-7-amido-4-methylcoumarin bos taurus 13.0 13.0 1 PMID:2604727 -3.4.22.27 benzoyl-phe-val-arg-7-amido-4-methylcoumarin oryctolagus cuniculus 0.02 0.02 1 PMID:3223923 -3.4.22.27 benzyloxycarbonyl-l-val-l-val-l-arg-7-amido-4-methylcoumarin bos taurus 40.5 27.8 2 PMID:12651112;PMID:2604727 -3.4.22.27 benzyloxycarbonyl-leu-arg-7-amido-4-methylcoumarin homo sapiens 3.5 3.15 2 PMID:31860022 -3.4.22.27 benzyloxycarbonyl-leu-leu-arg-7-amido-4-methylcoumarin homo sapiens 1.1 1.1 1 PMID:8444861 -3.4.22.27 benzyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin bos taurus 7.0 5.85 2 PMID:2604727;PMID:3814093 -3.4.22.27 benzyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin homo sapiens 2.0 1.8 2 PMID:8444861;PMID:8845771 -3.4.22.27 benzyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin oryctolagus cuniculus 0.0283 0.0283 1 PMID:3223923 -3.4.22.27 benzyloxycarbonyl-phe-val-arg-7-amido-4-methylcoumarin homo sapiens 2.9 2.9 1 PMID:8444861 -3.4.22.27 benzyloxycarbonyl-val-val-arg-7-amido-4-methylcoumarin canis lupus familiaris 12.4 12.4 1 PMID:12651112 -3.4.22.27 benzyloxycarbonyl-val-val-arg-7-amido-4-methylcoumarin homo sapiens 21.0 20.3 3 PMID:12651112;PMID:8444861;PMID:8845771 -3.4.22.27 benzyloxycarbonyl-val-val-arg-7-amido-4-methylcoumarin mus musculus 20.3 20.3 1 PMID:12651112 -3.4.22.27 benzyloxycarbonyl-val-val-arg-7-amido-4-methylcoumarin saimiri boliviensis 33.1 33.1 1 PMID:12651112 -3.4.22.27 butyloxycarbonyl-l-phe-l-phe-l-arg-7-amido-4-methylcoumarin homo sapiens 3.3 3.3 1 PMID:8444861 -3.4.22.27 butyloxycarbonyl-val-leu-lys-7-amido-4-methylcoumarin rattus norvegicus 65.0 47.5 2 PMID:11570845 -3.4.22.27 collagen oryctolagus cuniculus 5.48e-07 5.48e-07 1 PMID:3223923 -3.4.22.27 gelatin oryctolagus cuniculus 5.83e-10 5.83e-10 1 PMID:3223923 -3.4.22.27 grwhkfsvrwe homo sapiens 11.0 11.0 1 PMID:17081125 -3.4.22.27 grwhkisvrwe homo sapiens 3.0 3.0 1 PMID:17081125 -3.4.22.27 grwhklsvrwe homo sapiens 44.0 44.0 1 PMID:17081125 -3.4.22.27 o-aminobenzoic acid-leu-glu-gln-(n-[2,4-dinitrophenyl]ethylenediamine) homo sapiens 2.5 2.5 1 PMID:20045715 -3.4.22.27 tert-butyloxycarbonyl-phe-leu-arg-7-amido-4-methylcoumarin bos taurus 6.1 6.1 1 PMID:2604727 -3.4.22.27 tert-butyloxycarbonyl-phe-phe-arg-7-amido-4-methylcoumarin bos taurus 8.6 8.6 1 PMID:2604727 -3.4.22.28 (2-(n-methylamino)benzoyl)-iealfqgppk(2,4-dinitrophenyl)-fr enterovirus a71 0.0085 0.0085 1 PMID:25421478 -3.4.22.28 (e)-5-chloropyridin-3-yl 3-(furan-2-yl)acrylate hepatovirus a 0.00025 0.00025 1 PMID:18407505 -3.4.22.28 2-(n-methylamino)benzoyl-deameqgvsdyik-2,4-dinitrophenyl enterovirus a71 0.0005 0.0005 1 PMID:25421478 -3.4.22.28 2-(n-methylamino)benzoyl-iaalfqgppk(2,4-dinitrophenyl)fr enterovirus a71 0.0027 0.0027 1 PMID:25421478 -3.4.22.28 2-(n-methylamino)benzoyl-ieaafqgppk(2,4-dinitrophenyl)fr enterovirus a71 0.005 0.005 1 PMID:25421478 -3.4.22.28 2-(n-methylamino)benzoyl-iellfqgppk(2,4-dinitrophenyl)fr enterovirus a71 0.004 0.004 1 PMID:25421478 -3.4.22.28 2-(n-methylamino)benzoyl-rqavtqgfptelk-2,4-dinitrophenyl enterovirus a71 0.003 0.003 1 PMID:25421478 -3.4.22.28 2-(n-methylamino)benzoyl-rtatvqgpsldfk-2,4-dinitrophenyl enterovirus a71 0.0035 0.0035 1 PMID:25421478 -3.4.22.28 2-(n-methylamino)benzoyl-tsavlqsgfrk-(2,4-dinitrophenyl)-met enterovirus a71 0.0003 0.0003 1 PMID:25421478 -3.4.22.28 2-aminobenzoyl-aalfqgplq-eddnp enterovirus c 0.96 0.485 2 PMID:17002308 -3.4.22.28 2-aminobenzoyl-eaafqgplq-eddnp enterovirus c 3.34 1.71 2 PMID:17002308 -3.4.22.28 2-aminobenzoyl-ealaqgplq-eddnp enterovirus c 0.66 0.335 2 PMID:17002308 -3.4.22.28 2-aminobenzoyl-ealfqaplq-eddnp enterovirus c 0.34 0.34 1 PMID:17002308 -3.4.22.28 2-aminobenzoyl-ealfqgalq-eddnp enterovirus c 0.28 0.28 1 PMID:17002308 -3.4.22.28 2-aminobenzoyl-ealfqgpaq-eddnp enterovirus c 2.72 1.375 2 PMID:17002308 -3.4.22.28 2-aminobenzoyl-ealfqgplq-eddnp enterovirus c 2.02 0.46499999999999997 4 PMID:17002308 -3.4.22.28 4-(4-dimethylaminophenylazo)benzoic acid-ktsavlqsgfrkme-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid enterovirus 27.0 27.0 1 PMID:18583140 -3.4.22.28 5-bromopyridin-3-yl furan-3-carboxylate hepatovirus a 0.00119 0.00119 1 PMID:18407505 -3.4.22.28 5-chloropyridin-3-yl furan-2-carboxylate hepatovirus a 0.0011 0.0011 1 PMID:18407505 -3.4.22.28 ac-defqlq-4-nitroanilide southampton virus 0.33 0.33 1 PMID:21128685 -3.4.22.28 ac-efqlq-4-nitroanilide southampton virus 0.14 0.14 1 PMID:21128685 -3.4.22.28 ac-fqlq-4-nitroanilide southampton virus 0.08 0.08 1 PMID:21128685 -3.4.22.28 dabcyl-iealfqgppkfre-edans enterovirus a71 0.0028 0.0028 1 PMID:25421478 -3.4.22.28 dabcyl-rtatvqgpsldfke-edans enterovirus a71 0.002 0.002 1 PMID:25421478 -3.4.22.28 ealfq-4-nitroanilide rhinovirus b14 0.0042 0.0042 1 PMID:35597150 -3.4.22.28 mbp-levlfq-a rhinovirus b14 0.032 0.032 1 PMID:38521339 -3.4.22.28 mbp-levlfq-c rhinovirus b14 0.021 0.021 1 PMID:38521339 -3.4.22.28 mbp-levlfq-g rhinovirus b14 0.22 0.22 1 PMID:38521339 -3.4.22.28 mbp-levlfq-s rhinovirus b14 0.021 0.021 1 PMID:38521339 -3.4.22.28 n-acetyl-defqlq-4-nitroanilide norwalk virus 0.08 0.08 1 PMID:25275273 -3.4.22.28 slevlfqgpvrr human rhinovirus sp. 2.38 1.395 2 PMID:23395976 -3.4.22.28 tenlyfqsgtrr tobacco etch virus 0.22 0.128 2 PMID:23395976 -3.4.22.29 trpiitta-p-nitroanilide human rhinovirus sp. 0.00158 0.00158 1 PMID:9207196 -3.4.22.3 azocasein ficus carica 0.105 0.0665 4 PMID:38003281 -3.4.22.3 azocasein ficus pumila var. awkeotsang 0.166 0.166 1 PMID:36071690 -3.4.22.3 benzoyl-dl-arg-p-nitroanilide ficus sp. 0.0096 0.0096 1 PMID:4826886 -3.4.22.3 benzoyl-gly-p-nitrophenyl ester ficus sp. 3.41 3.16 4 PMID:5157300 -3.4.22.3 casein ficus johannis 32.9 32.9 1 * -3.4.22.3 n-benzyloxycarbonyl-d-ala p-nitrophenyl ester ficus sp. 0.45 0.45 1 PMID:4363754 -3.4.22.3 n-benzyloxycarbonyl-d-leu p-nitrophenyl ester ficus sp. 1.85 1.85 1 PMID:4363754 -3.4.22.3 n-benzyloxycarbonyl-d-phe p-nitrophenyl ester ficus sp. 1.2 1.2 1 PMID:4363754 -3.4.22.3 n-benzyloxycarbonyl-d-tyr p-nitrophenyl ester ficus sp. 0.92 0.92 1 PMID:4363754 -3.4.22.3 nalpha-benzoyl-l-arg ethyl ester ficus sp. 1.29 1.29 1 PMID:4826886 -3.4.22.3 nalpha-carbobenzoxy-ala p-nitrophenyl ester ficus sp. 31.0 30.4 2 PMID:4363754 -3.4.22.3 nalpha-carbobenzoxy-gly p-nitrophenyl ester ficus sp. 12.4 9.25 3 PMID:4363754;PMID:4826886 -3.4.22.3 nalpha-carbobenzoxy-glycylglycine p-nitrophenyl ester ficus sp. 7.45 7.45 1 PMID:4363754 -3.4.22.3 nalpha-carbobenzoxy-leu p-nitrophenyl ester ficus sp. 4.5 4.5 1 PMID:4363754 -3.4.22.3 nalpha-carbobenzoxy-lys p-nitrophenyl ester ficus sp. 55.0 45.0 2 PMID:4363754 -3.4.22.3 nalpha-carbobenzoxy-phe p-nitrophenyl ester ficus sp. 2.83 2.83 1 PMID:4363754 -3.4.22.3 nalpha-carbobenzoxy-tyr p-nitrophenyl ester ficus sp. 2.27 2.27 1 PMID:4363754 -3.4.22.3 nalpha-carbobenzoxy-val p-nitrophenyl ester ficus sp. 1.02 1.02 1 PMID:4363754 -3.4.22.3 p-nitrophenyl n-acetylglycinate ficus sp. 2.84 2.57 2 PMID:4363754 -3.4.22.3 p-nitrophenyl n-benzoylglycinate ficus sp. 53.6 30.66 2 PMID:4363754 -3.4.22.3 p-nitrophenyl n-benzyloxycarbonylglycinate ficus sp. 95.7 54.5 2 PMID:4363754 -3.4.22.3 p-nitrophenyl n-formylglycinate ficus sp. 2.5 2.5 1 PMID:4363754 -3.4.22.3 p-nitrophenyl n-trans-cinnamoylglycinate ficus sp. 123.0 104.7 2 PMID:4363754 -3.4.22.30 benzoyl-dl-arg 4-nitroanilide carica papaya 0.15 0.14500000000000002 2 PMID:3513753 -3.4.22.30 benzyloxycarbonyl-lys nitrophenyl ester carica papaya 49.0 49.0 1 PMID:3513753 -3.4.22.30 benzyloxycarbonyl-phe-arg 4-methylcoumarin 7-amide carica papaya 7.1 7.1 1 PMID:3919769 -3.4.22.30 n-benzyloxycarbonyl-gly 4-nitrophenyl ester carica papaya 16.7 16.7 1 PMID:6378179 -3.4.22.30 succinyl-albumin carica papaya 2.6 2.6 1 PMID:3919769 -3.4.22.31 alk ananas comosus 3.58 3.58 1 PMID:31306685 -3.4.22.31 alr ananas comosus 4.96 4.96 1 PMID:31306685 -3.4.22.31 benzoyl-phe-val-arg 4-methylcoumarin 7-amide ananas comosus 63.8 63.8 1 PMID:2327970;PMID:7845232 -3.4.22.31 benzoyl-phe-val-arg 4-nitroanilide ananas comosus 10.9 10.9 1 PMID:8053898 -3.4.22.31 benzyloxycarbonyl-arg-arg 4-methylcoumarin 7-amide ananas comosus 0.321 0.321 1 PMID:2327970;PMID:3196029 -3.4.22.31 benzyloxycarbonyl-arg-arg 4-nitroanilide ananas comosus 0.13 0.13 1 PMID:8053898 -3.4.22.31 benzyloxycarbonyl-arg-arg-7-amido-4-methylcoumarin ananas comosus 0.16 0.16 1 PMID:31306685 -3.4.22.31 benzyloxycarbonyl-gly-phe-citrulline 4-methylcoumarin 7-amide ananas comosus 3.54 3.54 1 PMID:2327970 -3.4.22.31 benzyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin ananas comosus 1.58 1.58 1 PMID:31306685 -3.4.22.31 benzyloxycarbonyl-phe-citrulline 4-methylcoumarin 7-amide ananas comosus 21.0 21.0 1 PMID:2327970 -3.4.22.31 benzyloxycarbonyl-phe-val-arg-7-amido-4-methylcoumarin ananas comosus 13.9 10.45 2 PMID:2327970;PMID:31306685;PMID:3196029 -3.4.22.31 plk ananas comosus 6.08 6.08 1 PMID:31306685 -3.4.22.31 pln ananas comosus 0.36 0.36 1 PMID:31306685 -3.4.22.31 plq ananas comosus 9.8 9.8 1 PMID:31306685 -3.4.22.31 plr ananas comosus 5.62 5.62 1 PMID:31306685 -3.4.22.31 vlk ananas comosus 6.29 6.29 1 PMID:31306685 -3.4.22.31 vlr ananas comosus 7.13 7.13 1 PMID:31306685 -3.4.22.32 acetyl-gly ethyl ester ananas comosus 0.55 0.55 1 * -3.4.22.32 benzoyl-gly ethyl ester ananas comosus 0.36 0.24 3 PMID:4761326 -3.4.22.32 benzoyl-l-arg amide ananas comosus 0.027 0.0046 5 PMID:5073324 -3.4.22.32 benzoyl-l-arg ethyl ester ananas comosus 0.5 0.42 3 PMID:4761326 -3.4.22.32 benzoyl-l-arg methyl ester ananas comosus 0.11 0.11 1 * -3.4.22.32 benzoyl-phe-val-arg 4-methylcoumarin 7-amide ananas comosus 0.893 0.893 1 PMID:2327970 -3.4.22.32 benzyl-phe-val-arg-4-nitroanilide ananas comosus 20.0 20.0 1 * -3.4.22.32 benzyloxycarbonyl-arg-arg 4-methylcoumarin 7-amide ananas comosus 27.0 27.0 1 PMID:2327970;PMID:3196029;PMID:7845232 -3.4.22.32 benzyloxycarbonyl-arg-arg-nh-4-methylcoumarin 7-amide ananas comosus 0.04 0.032 2 PMID:9619588 -3.4.22.32 benzyloxycarbonyl-gly 4-nitrophenyl ester ananas comosus 3.35 2.55 2 PMID:1124936 -3.4.22.32 benzyloxycarbonyl-gly-phe-citrulline 4-methylcoumarin 7-amide ananas comosus 0.12 0.12 1 PMID:2327970 -3.4.22.32 benzyloxycarbonyl-l-ala 4-nitrophenyl ester ananas comosus 8.3 5.4 2 PMID:1124936 -3.4.22.32 benzyloxycarbonyl-l-asn 4-nitrophenyl ester ananas comosus 1.5 1.5 1 PMID:1124936 -3.4.22.32 benzyloxycarbonyl-l-lys 4-nitrophenyl ester ananas comosus 9.8 8.600000000000001 2 PMID:1124936 -3.4.22.32 benzyloxycarbonyl-l-tyr 4-nitrophenyl ester ananas comosus 0.44 0.42000000000000004 2 PMID:1124936 -3.4.22.32 benzyloxycarbonyl-phe-arg 4-methylcoumarin 7-amide ananas comosus 0.13 0.13 1 PMID:2327970;PMID:3196029 -3.4.22.32 benzyloxycarbonyl-phe-arg-nh-4-methylcoumarin 7-amide ananas comosus 6.08 0.56 3 PMID:9619588 -3.4.22.32 benzyloxycarbonyl-phe-val-arg-nh-4-methylcoumarin 7-amide ananas comosus 6.4 5.75 2 PMID:9619588 -3.4.22.32 bz-phe-val-arg-4-nitroanilide ananas comosus 21.45 18.35 23 PMID:21381670;PMID:23011793 -3.4.22.32 casein ananas comosus 18.08 6.355 6 PMID:17172264 -3.4.22.32 l-pyroglutamyl-l-phe-l-leu 4-nitroanilide ananas comosus 3.94 0.87 3 PMID:5073324;PMID:7779262 -3.4.22.32 milk protein concentrate ananas comosus 0.0041 0.0041 1 PMID:38231667 -3.4.22.32 n-benzyloxycarbonyl-l-phe-l-ser methyl ester ananas comosus 3.4 3.4 1 PMID:1012011 -3.4.22.32 tosyl-l-lys methyl ester ananas comosus 0.035 0.035 1 * -3.4.22.32 whey protein isolate ananas comosus 0.0053 0.0053 1 PMID:38231667 -3.4.22.33 n-carbobenzoxyglycine 4-nitrophenyl ester ananas comosus 1.93 0.2 3 PMID:33713245;PMID:36144767 -3.4.22.33 n-carbobenzoxyglycine p-nitrophenyl ester ananas comosus 1.93 1.93 1 PMID:33713245 -3.4.22.33 nalpha-benzoyl-arg amide ananas comosus 0.033 0.027 3 PMID:5073324 -3.4.22.34 benzyloxycarbonyl-ala-ala-asn-4-methylcoumarin-7-amide bos taurus 17.9 17.9 1 PMID:11983426 -3.4.22.34 benzyloxycarbonyl-ala-ala-asn-4-methylcoumarin-7-amide sus scrofa 46.0 46.0 1 PMID:9065484 -3.4.22.34 benzyloxycarbonyl-ala-ala-asn-7-amido-4-methylcoumarin dictyocaulus viviparus 0.33 0.33 1 PMID:28942744 -3.4.22.34 benzyloxycarbonyl-ile-ser-asn-4-methylcoumarin-7-amide bos taurus 0.1 0.1 1 PMID:11983426 -3.4.22.35 benzyloxycarbonyl-arg-arg 4-methylcoumarin 7-amide entamoeba histolytica 130.0 130.0 1 PMID:2898937 -3.4.22.35 benzyloxycarbonyl-phe-arg 4-methylcoumarin 7-amide entamoeba histolytica 0.4 0.4 1 PMID:2898937 -3.4.22.36 4-[[4'-(dimethylamino)phenyl]azo]-benzoic acid-yvadapv-5-[(2'-aminoethyl)-amino]naphthalenesulfonic acid homo sapiens 0.41 0.41 1 PMID:9054418 -3.4.22.36 ac-fead-7-amido-4-carbamoylmethylcoumarin canis lupus familiaris 1.22 1.22 2 PMID:35427646 -3.4.22.36 ac-llsdgid-7-amido-4-carbamoylmethylcoumarin canis lupus familiaris 4.93 4.93 1 PMID:35427646 -3.4.22.36 ac-lsdgide-7-amido-4-carbamoylmethylcoumarin canis lupus familiaris 0.3 0.3 1 PMID:35427646 -3.4.22.36 ac-sdgidee-7-amido-4-carbamoylmethylcoumarin canis lupus familiaris 0.02 0.02 1 PMID:35427646 -3.4.22.36 ac-sllsdg-7-amido-4-carbamoylmethylcoumarin canis lupus familiaris 1.06 1.06 1 PMID:35427646 -3.4.22.36 ac-sllsdgi-7-amido-4-carbamoylmethylcoumarin canis lupus familiaris 3.75 3.75 1 PMID:35427646 -3.4.22.36 ac-sllsdgid-7-amido-4-carbamoylmethylcoumarin canis lupus familiaris 2.23 2.23 1 PMID:35427646 -3.4.22.36 ac-sllsdgide-7-amido-4-carbamoylmethylcoumarin canis lupus familiaris 3.0 3.0 1 PMID:35427646 -3.4.22.36 ac-sllsdgidee-7-amido-4-carbamoylmethylcoumarin canis lupus familiaris 2.72 2.72 1 PMID:35427646 -3.4.22.36 ac-wehd-7-amido-4-trifluoromethylcoumarin canis lupus familiaris 8.87 8.87 2 PMID:35427646 -3.4.22.36 ac-wqpd-7-amido-4-carbamoylmethylcoumarin canis lupus familiaris 2.96 2.96 2 PMID:35427646 -3.4.22.36 acetyl-fead-7-amido-4-methylcoumarin canis lupus familiaris 1.22 1.22 1 PMID:35427646 -3.4.22.36 acetyl-wehd-7-amido-4-methylcoumarin canis lupus familiaris 8.87 8.87 1 PMID:35427646 -3.4.22.36 acetyl-wehd-7-amido-4-methylcoumarin homo sapiens 13.0 13.0 1 PMID:10381624 -3.4.22.36 acetyl-wqpd-7-amido-4-methylcoumarin canis lupus familiaris 2.96 2.96 1 PMID:35427646 -3.4.22.36 acetyl-yvad-7-amido-4-methylcoumarin homo sapiens 1.0 1.0 1 PMID:9054418 -3.4.22.36 llsdgid canis lupus familiaris 4.93 4.93 2 PMID:35427646 -3.4.22.36 lsdgide canis lupus familiaris 0.3 0.3 2 PMID:35427646 -3.4.22.36 pro-interleukin-1beta homo sapiens 1.2 1.2 1 PMID:9054418 -3.4.22.36 sdgidee canis lupus familiaris 0.02 0.02 2 PMID:35427646 -3.4.22.36 sllsdg canis lupus familiaris 1.06 1.06 2 PMID:35427646 -3.4.22.36 sllsdgi canis lupus familiaris 3.75 3.75 2 PMID:35427646 -3.4.22.36 sllsdgid canis lupus familiaris 2.23 2.23 2 PMID:35427646 -3.4.22.36 sllsdgide canis lupus familiaris 3.0 3.0 2 PMID:35427646 -3.4.22.36 sllsdgidee canis lupus familiaris 2.72 2.72 2 PMID:35427646 -3.4.22.36 succinyl-yvad-4-nitroanilide homo sapiens 1.6 1.3 2 PMID:9054418;PMID:9578463 -3.4.22.36 succinyl-yvad-7-amido-4-methylcoumarin homo sapiens 0.35 0.35 1 PMID:9578463 -3.4.22.37 prothrombin porphyromonas gingivalis 0.32 0.198 2 PMID:11278315 -3.4.22.38 2,2'-n,n'-bis(benzyloxycarbonyl)-l-leucinylcarbohydrazide homo sapiens 0.00011 0.00011 1 PMID:10625455 -3.4.22.38 abz-hpggpq-(3 no2-tyr) homo sapiens 1.8 1.8 1 PMID:31740411 -3.4.22.38 abz-hpggpq-(3 no2-tyr) rattus norvegicus 0.005 0.005 1 PMID:31740411 -3.4.22.38 abz-rppgfspfr-(3-no2-tyr) homo sapiens 1.1 1.1 1 PMID:31740411 -3.4.22.38 abz-rppgfspfr-(3-no2-tyr) rattus norvegicus 0.2 0.2 1 PMID:31740411 -3.4.22.38 acetyl-phe-arg 4-methylcoumarin 7-amide homo sapiens 0.016 0.016 1 PMID:8647860 -3.4.22.38 benzoyl-arg 4-methylcoumarin 7-amide homo sapiens 0.092 0.092 1 PMID:8647860 -3.4.22.38 benzoyl-phe-val-arg 4-methylcoumarin 7-amide homo sapiens 0.39 0.39 1 PMID:8647860 -3.4.22.38 benzyloxycarbonyl-arg-arg 4-methylcoumarin 7-amide homo sapiens 0.0005 0.0005 1 PMID:8567669 -3.4.22.38 benzyloxycarbonyl-glu-arg 4-methylcoumarin 7-amide homo sapiens 0.037 0.037 1 PMID:8647860 -3.4.22.38 benzyloxycarbonyl-gly-pro-arg-7-amido-4-methylcoumarin homo sapiens 2.4 2.4 1 PMID:31740411 -3.4.22.38 benzyloxycarbonyl-gly-pro-arg-7-amido-4-methylcoumarin rattus norvegicus 0.07 0.07 1 PMID:31740411 -3.4.22.38 benzyloxycarbonyl-leu-arg 4-methylcoumarin 7-amide homo sapiens 3.4 2.19 2 PMID:8567669;PMID:8647860 -3.4.22.38 benzyloxycarbonyl-leu-arg-7-amido-4-methylcoumarin homo sapiens 12.7 12.7 1 PMID:31740411 -3.4.22.38 benzyloxycarbonyl-leu-arg-7-amido-4-methylcoumarin rattus norvegicus 1.9 1.9 1 PMID:31740411 -3.4.22.38 benzyloxycarbonyl-leu-leu-arg 4-methylcoumarin 7-amide homo sapiens 0.078 0.049 2 PMID:8567669;PMID:8647860 -3.4.22.38 benzyloxycarbonyl-phe-arg 4-methylcoumarin 7-amide homo sapiens 3.5 2.2 2 PMID:8567669;PMID:8647860 -3.4.22.38 benzyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin homo sapiens 91.0 39.0 3 PMID:20450492;PMID:31740411 -3.4.22.38 benzyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin rattus norvegicus 0.13 0.13 1 PMID:31740411 -3.4.22.38 benzyloxycarbonyl-val-arg 4-methylcoumarin 7-amide homo sapiens 2.9 1.98 2 PMID:8567669;PMID:8647860 -3.4.22.38 benzyloxycarbonyl-val-val-arg 4-methylcoumarin 7-amide homo sapiens 0.021 0.0155 2 PMID:8567669;PMID:8647860 -3.4.22.38 benzyloxycarbonyl-val-val-arg-7-amido-4-methylcoumarin homo sapiens 0.37 0.28 2 PMID:20450492 -3.4.22.38 carbobenzoxy-phe-arg-7-amido-4-methylcoumarin homo sapiens 17.0 17.0 1 PMID:25279554 -3.4.22.38 carbobenzyloxy-leu-arg-4-methylcoumaryl-7-amide homo sapiens 56.1 56.1 1 PMID:18664521 -3.4.22.38 carbobenzyloxy-leu-arg-4-methylcoumaryl-7-amide rattus norvegicus 95.7 95.7 1 PMID:18664521 -3.4.22.38 n-[(1s)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)biphenyl-4-yl]ethyl]-l-leucyl-l-alaninamide homo sapiens 23.2 23.2 1 PMID:17544269 -3.4.22.38 n-[(1s)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)biphenyl-4-yl]ethyl]-l-leucyl-l-methioninamide homo sapiens 3.25 3.25 1 PMID:17544269 -3.4.22.38 n-[(1s)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)biphenyl-4-yl]ethyl]-l-leucylglycinamide homo sapiens 23.2 23.2 1 PMID:17544269 -3.4.22.38 pro-phe-arg 4-methylcoumarin 7-amide homo sapiens 0.16 0.16 1 PMID:8647860 -3.4.22.38 succinyl-leu-tyr 4-methylcoumarin 7-amide homo sapiens 0.008 0.008 1 PMID:8647860 -3.4.22.38 tert-butyloxycarbonyl-val-leu-lys 4-methylcoumarin 7-amide homo sapiens 0.52 0.52 1 PMID:8647860 -3.4.22.38 tert-butyloxycarbonyl-val-pro-arg 4-methylcoumarin 7-amide homo sapiens 0.083 0.083 1 PMID:8647860 -3.4.22.38 tosyl-gly-pro-arg 4-methylcoumarin 7-amide homo sapiens 2.2 2.2 1 PMID:8647860 -3.4.22.38 z-gly-pro-arg-7-amido-4-methylcoumarin homo sapiens 2.9 2.65 2 PMID:21193413;PMID:31740411 -3.4.22.38 z-gly-pro-arg-7-amido-4-methylcoumarin rattus norvegicus 0.07 0.07 1 PMID:31740411 -3.4.22.38 z-leu-arg-7-amido-4-methylcoumarin homo sapiens 79.0 12.7 3 PMID:17544269;PMID:21193413;PMID:31740411 -3.4.22.38 z-leu-arg-7-amido-4-methylcoumarin rattus norvegicus 1.9 1.9 1 PMID:31740411 -3.4.22.38 z-phe-arg-7-amido-4-methylcoumarin homo sapiens 12.8 12.8 1 PMID:31740411 -3.4.22.38 z-phe-arg-7-amido-4-methylcoumarin rattus norvegicus 0.13 0.13 1 PMID:31740411 -3.4.22.39 (leu-arg-gly-gly-nh)2-rhodamine human adenovirus sp. 6.0 0.271 5 PMID:11683632 -3.4.22.40 6'-deoxy bleomycin a2 homo sapiens 4.9 4.9 1 PMID:29730026 -3.4.22.40 6'-deoxy bleomycin z homo sapiens 15.0 15.0 1 PMID:29730026 -3.4.22.40 6'-deoxy tallysomycin h1 homo sapiens 2.5 2.5 1 PMID:29730026 -3.4.22.40 bleomycin a2 homo sapiens 4.0 4.0 1 PMID:29730026 -3.4.22.40 bleomycin b2 homo sapiens 11.0 11.0 1 PMID:29730026 -3.4.22.40 bleomycin z homo sapiens 9.8 9.8 1 PMID:29730026 -3.4.22.40 tallysomycin h1 homo sapiens 2.4 2.4 1 PMID:29730026 -3.4.22.41 benzyloxycarbonyl-phe-arg-4-methylcoumaryl-7-amide homo sapiens 2.9 2.9 1 PMID:12454497 -3.4.22.41 n-benzyloxycarbonyl-l-arg-l-arg-4-methylcoumarin 7-amide homo sapiens 0.2 0.2 1 PMID:9822672 -3.4.22.41 n-benzyloxycarbonyl-l-leu-l-arg-4-methylcoumarin 7-amide homo sapiens 1.3 1.3 1 PMID:9822672 -3.4.22.41 n-benzyloxycarbonyl-l-phe-l-arg-4-methylcoumarin 7-amide homo sapiens 2.5 2.5 1 PMID:9822672 -3.4.22.41 n-benzyloxycarbonyl-l-val-l-arg-4-methylcoumarin 7-amide homo sapiens 1.3 1.3 1 PMID:9822672 -3.4.22.43 2-aminobenzoyl-alrsskq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 4.0 4.0 1 PMID:15369827 -3.4.22.43 2-aminobenzoyl-ee-epsilon-amino-caproic acid-elklq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.3 1.3 1 PMID:15369827 -3.4.22.43 2-aminobenzoyl-elklq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.6 0.6 1 PMID:15369827 -3.4.22.43 2-aminobenzoyl-kk-epsilon-amino-caproic acid-elklq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.7 1.7 1 PMID:15369827 -3.4.22.43 2-aminobenzoyl-klrsikq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.5 1.5 1 PMID:15369827 -3.4.22.43 2-aminobenzoyl-klrsskq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.3 1.3 1 PMID:15369827 -3.4.22.43 2-aminobenzoyl-klrvskq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.9 0.9 1 PMID:15369827 -3.4.22.43 benzyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin homo sapiens 156.0 5.4 7 PMID:22100277;PMID:33278943 -3.4.22.43 benzyloxycarbonyl-val-val-arg-7-amido-4-methylcoumarin homo sapiens 19.0 19.0 1 PMID:22100277 -3.4.22.43 z-phe-arg-4-methyl-7-coumaryl amide homo sapiens 3.7 3.55 2 PMID:15192101 -3.4.22.44 acetyl-arg-glu-thr-val-arg-phe-gln-ser-asp-amide tobacco vein mottling virus 0.079 0.079 1 PMID:10850655 -3.4.22.44 acetyl-asn-asn-val-arg-phe-gln-ser-leu-amide tobacco vein mottling virus 0.071 0.071 1 PMID:10850655 -3.4.22.44 acetyl-glu-pro-thr-val-tyr-his-gln-thr-leu-amide turnip mosaic potyvirus 1.01 0.325 8 PMID:8661434;PMID:8955037 -3.4.22.44 norovirus p domain-fused rna interaction-mediated domain tobacco etch virus 0.00091 0.00091 1 PMID:32129006 -3.4.22.44 pro-thr-thr-glu-leu-tyr-phe-gln-ser-gly-thr-val-asp-arg-arg tobacco etch virus 0.18 0.1065 2 PMID:7793070 -3.4.22.44 tetvrfqsgtrr tobacco vein mottling virus 0.092 0.092 1 PMID:20862670 -3.4.22.44 wdggevahqagesv chilli veinal mottle virus 0.23 0.132 2 PMID:22099968 -3.4.22.47 hemoglobin porphyromonas gingivalis 9.4 9.4 1 PMID:11544223 -3.4.22.48 2-aminobenzoyl-ile-ala-ala-gly-5-amino-2-nitrobenzoylamide staphylococcus aureus 0.886 0.056 3 PMID:21802486 -3.4.22.48 2-aminobenzoyl-ile-ala-lys-asp-5-amino-2-nitrobenzoylamide staphylococcus aureus 0.089 0.032 3 PMID:21802486 -3.4.22.48 2-aminobenzoyl-phe-gly-ala-lys-5-amino-2-nitrobenzoylamide staphylococcus aureus 0.716 0.023 3 PMID:21802486 -3.4.22.48 n-benzyloxycarbonyl-phe-leu-glu-nh-p-nitroanilide staphylococcus aureus 0.16 0.16 1 * -3.4.22.48 n-suc-gly-phe-gly-p-nitroanilide staphylococcus aureus 0.2 0.2 1 PMID:17261086 -3.4.22.50 z-arg-arg-7-amido-4-methylcoumarin autographa californica nucleopolyhedrovirus 0.73 0.73 1 PMID:8590630 -3.4.22.50 z-leu-arg 7-amido-4-methylcoumarin autographa californica nucleopolyhedrovirus 0.73 0.73 1 PMID:8590630 -3.4.22.50 z-phe-arg 7-amido-4-methylcoumarin autographa californica nucleopolyhedrovirus 0.95 0.95 1 PMID:8590630 -3.4.22.50 z-val-arg-7-amido-4-methylcoumarin autographa californica nucleopolyhedrovirus 0.94 0.94 1 PMID:8590630 -3.4.22.50 z-val-val-arg 7-amido-4-methylcoumarin autographa californica nucleopolyhedrovirus 0.51 0.51 1 PMID:8590630 -3.4.22.51 2-aminobenzoic acid-klrfskq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 0.08 0.07415 2 PMID:11737212 -3.4.22.51 2-aminobenzoyl-arf-(2,4-dinitrophenyl)-epsilon-nh2-lysine-oh trypanosoma cruzi 0.1 0.1 1 PMID:15009216 -3.4.22.51 2-aminobenzoyl-fra-(2,4-dinitrophenyl)-epsilon-nh2-lysine-nh2 trypanosoma cruzi 4.2 4.2 1 PMID:15009216 -3.4.22.51 2-aminobenzoyl-fra-(2,4-dinitrophenyl)-epsilon-nh2-lysine-oh trypanosoma cruzi 5.5 5.5 1 PMID:15009216 -3.4.22.51 2-aminobenzoyl-frf-(2,4-dinitrophenyl)-epsilon-nh2-lysine-oh trypanosoma cruzi 2.9 2.9 1 PMID:15009216 -3.4.22.51 2-aminobenzoyl-lgmislmkrpq-n-(2,4-dinitrophenyl)ethylenediamine trypanosoma cruzi 0.0583 0.04165 2 PMID:11726662 -3.4.22.51 2-aminobenzoyl-phe-arg-(2,4-dinitrophenyl)-epsilon-nh2-lysine-pro-oh trypanosoma cruzi 1.4 1.4 1 PMID:15009216 -3.4.22.51 2-aminobenzoyl-phe-arg-(2,4-dinitrophenyl)-epsilon-nh2-lysine-trp-oh trypanosoma cruzi 3.4 3.4 1 PMID:15009216 -3.4.22.51 2-aminobenzoyl-rrf-(2,4-dinitrophenyl)-epsilon-nh2-lysine-oh trypanosoma cruzi 0.13 0.13 1 PMID:15009216 -3.4.22.51 benzoyl-his-arg-7-amido-4-methylcoumarin trypanosoma cruzi 0.172 0.172 1 PMID:11606223 -3.4.22.51 benzoyl-phe-arg-7-amido-4-methylcoumarin trypanosoma cruzi 0.193 0.055 3 PMID:11606223;PMID:11737212 -3.4.22.51 benzoyl-rr-aminomethyl coumarin trypanosoma cruzi 0.0783 0.0783 1 PMID:11606223 -3.4.22.51 benzyloxycarbonyl-arg-ala-7-amido-4-methylcoumarin trypanosoma cruzi 0.89 0.89 1 PMID:29336553 -3.4.22.51 benzyloxycarbonyl-arg-arg-7-amido-4-methylcoumarin trypanosoma cruzi 8.0 5.85 14 PMID:29336553 -3.4.22.51 benzyloxycarbonyl-fr-aminomethyl coumarin trypanosoma cruzi 0.158 0.158 1 PMID:11606223 -3.4.22.51 benzyloxycarbonyl-phe-arg-7-amido-4-methylcoumarin trypanosoma cruzi 17.0 14.0 13 PMID:29336553 -3.4.22.51 benzyloxycarbonyl-phe-arg-aminomethyl coumarin trypanosoma cruzi 4.49 3.325 2 PMID:8454586 -3.4.22.51 epsilon-nh2(capryl)-l-(sbzl)c-7-amido-4-methylcoumarin trypanosoma cruzi 10.8 10.8 1 PMID:16734782 -3.4.22.51 n-alpha-benzyloxy-carbonyl-l-phenylalanyl-l-alanine-(7-amido-4-methylcoumarin) trypanosoma cruzi 0.14 0.14 1 PMID:15723522 -3.4.22.51 n-alpha-benzyloxycarbonyl-l-arginyl-l-alanine-(7-amido-4-methylcoumarin) trypanosoma cruzi 0.15 0.15 1 PMID:15723522 -3.4.22.51 n-alpha-benzyloxycarbonyl-l-tyrosyl-l-alanine-(7-amido-4-methylcoumarin) trypanosoma cruzi 0.13 0.13 1 PMID:15723522 -3.4.22.51 n-carbobenzoxy-arg-arg-2-(4-methoxy)-naphthylamide trypanosoma cruzi 0.0805 0.0805 1 PMID:2407295 -3.4.22.51 o-aminobenzoyl-alrfskq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 4.5 4.5 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-hlrfskq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 5.6 5.6 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-karfskq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 1.3 1.3 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-kfrfskq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 1.9 1.9 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-klffskq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 2.5 2.5 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-klgfskq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 5.6 5.6 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-klkfskq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 14.2 14.2 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-klrfakq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 15.2 11.7 2 PMID:16734782 -3.4.22.51 o-aminobenzoyl-klrffkq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 9.7 9.7 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-klrfpkq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 2.8 2.8 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-klrfskq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 6.9 5.6 2 PMID:16734782 -3.4.22.51 o-aminobenzoyl-klrfspq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 13.9 13.9 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-klrfsrq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 12.5 12.5 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-klrlskq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 9.1 9.1 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-klrrskq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 1.9 1.9 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-kprfskq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 0.5 0.5 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-krrfskq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 7.7 7.7 1 PMID:16734782 -3.4.22.51 o-aminobenzoyl-llrfskq-n-(2,4-dinitrophenyl)-ethylenediamine trypanosoma cruzi 6.7 6.7 1 PMID:16734782 -3.4.22.52 2-aminobenzoyl-evygmmy(3-no2)-oh homo sapiens 0.025 0.025 1 PMID:20166953 -3.4.22.52 k-(5(6)-carboxyfluorescein)-evygmmk(4-(4-dimethylaminophenylazo)benzoyl)-oh homo sapiens 0.11 0.11 1 PMID:20166953 -3.4.22.52 n-benzyloxycarbonyl-l-leu-l-arg-4-methoxy-2-naphthylamide homo sapiens 0.52 0.52 1 PMID:20166953 -3.4.22.52 n-benzyloxycarbonyl-l-leu-l-arg-7-amido-4-methylcoumarin homo sapiens 0.02 0.02 1 PMID:20166953 -3.4.22.52 n-benzyloxycarbonyl-l-leu-l-arg-7-amido-4-trifluoromethylcoumarin homo sapiens 0.07 0.07 1 PMID:20166953 -3.4.22.52 succinyl-l-leu-l-leu-l-val-7-amido-4-methylcoumarin homo sapiens 0.29 0.29 1 PMID:20166953 -3.4.22.52 succinyl-l-leu-l-leu-l-val-l-tyr-7-amido-4-methylcoumarin homo sapiens 0.029 0.029 1 PMID:20166953 -3.4.22.52 succinyl-l-leu-l-met-7-amido-4-methylcoumarin homo sapiens 0.062 0.062 1 PMID:20166953 -3.4.22.52 succinyl-l-leu-l-tyr-4-methoxy-2-naphthylamide homo sapiens 0.12 0.12 1 PMID:20166953 -3.4.22.52 succinyl-l-leu-l-tyr-7-amido-4-methylcoumarin homo sapiens 0.37 0.37 1 PMID:20166953 -3.4.22.52 tert-butyloxycarbonyl-l-val-l-leu-l-lys-7-amido-4-methylcoumarin homo sapiens 0.49 0.49 1 PMID:20166953 -3.4.22.53 boc-val-leu-lys-methylcoumarin struthio camelus 0.341 0.341 1 PMID:11854033 -3.4.22.53 succinyl-leu-leu-val-tyr-7-amido-4-methylcoumarin bos taurus 0.063 0.0625 2 PMID:20123702 -3.4.22.53 succinyl-leu-leu-val-tyr-methylcoumarin struthio camelus 0.0394 0.0394 1 PMID:11854033 -3.4.22.53 succinyl-leu-met-7-amido-4-methylcoumarin bos taurus 0.189 0.1875 2 PMID:20123702 -3.4.22.53 succinyl-leu-tyr-7-amido-4-methylcoumarin bos taurus 0.084 0.0835 2 PMID:20123702 -3.4.22.53 succinyl-leu-tyr-7-amido-4-methylcoumarin struthio camelus 0.04 0.04 1 PMID:11854033 -3.4.22.53 t-boc-leu-met-methylcoumarin struthio camelus 0.546 0.546 1 PMID:11854033 -3.4.22.53 t-butyloxycarbonyl-val-leu-lys-7-amido-4-methylcoumarin bos taurus 1.08 1.07 2 PMID:20123702 -3.4.22.55 abz-vdvadfa-dap(dnp) homo sapiens 7.9 3.6 3 PMID:33255244 -3.4.22.55 abz-vdvadga-dap(dnp) homo sapiens 270.0 190.0 3 PMID:33255244 -3.4.22.55 abz-vdvadpa-dap(dnp) homo sapiens 0.0099 0.005355 2 PMID:33255244 -3.4.22.55 abz-vdvadqa-dap(dnp) homo sapiens 4.6 2.1 3 PMID:33255244 -3.4.22.55 abz-vdvadva-dap(dnp) homo sapiens 54.0 1.7 3 PMID:33255244 -3.4.22.55 ac-vdvad-7-amido-4-trifluoromethylcoumarin homo sapiens 0.6 0.6 1 PMID:21828056 -3.4.22.56 acetyl-devd-7-amido-4-methylcoumarin homo sapiens 14.0 11.55 2 PMID:10381624 -3.4.22.56 acetyl-l-asp-l-glu-l-val-l-asp-4-nitroanilide homo sapiens 0.88 0.88 1 PMID:16781734 -3.4.22.56 acetyl-l-asp-l-glu-l-val-l-asp-7-amido-4-methylcoumarin homo sapiens 6.01 3.17 2 PMID:16787777 -3.4.22.56 acetyl-l-asp-l-met-l-gln-l-asp-4-nitroanilide homo sapiens 3.5 3.5 1 PMID:16781734 -3.4.22.56 acetyl-l-asp-l-val-l-ala-l-asp-4-nitroanilide homo sapiens 0.9 0.9 1 PMID:16781734 -3.4.22.56 acetyl-l-leu-l-asp-l-val-l-ala-l-asp-4-nitroanilide homo sapiens 0.84 0.84 1 PMID:16781734 -3.4.22.56 acetyl-l-val-l-asp-l-val-l-ala-l-asp-4-nitroanilide homo sapiens 0.8 0.8 1 PMID:16781734 -3.4.22.56 benzoyl-l-asp-l-glu-l-val-l-asp-7-amido-4-methylcoumarin homo sapiens 7.08 0.55 3 PMID:16787777 -3.4.22.56 n-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-asp-ala-pro-asp-6-aminohexanoyl-n6-[methyl red]-lys-[n-(6-aminohexyl)-gly]8-n2-(6-aminohexyl)-gly-nh2 homo sapiens 0.0217 0.0217 1 PMID:27168077 -3.4.22.56 n-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-asp-ala-val-asp-6-aminohexanoyl-n6-[methyl red]-lys-[n-(6-aminohexyl)-gly]8-n2-(6-aminohexyl)-gly-nh2 homo sapiens 0.0183 0.0183 1 PMID:27168077 -3.4.22.56 n-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-asp-asn-pro-asp-6-aminohexanoyl-n6-[methyl red]-lys-[n-(6-aminohexyl)-gly]8-n2-(6-aminohexyl)-gly-nh2 homo sapiens 0.017 0.017 1 PMID:27168077 -3.4.22.56 n-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-asp-asn-val-asp-6-aminohexanoyl-n6-[methyl red]-lys-[n-(6-aminohexyl)-gly]8-n2-(6-aminohexyl)-gly-nh2 homo sapiens 0.013 0.013 1 PMID:27168077 -3.4.22.56 n-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-asp-glu-val-asp-6-aminohexanoyl-n6-[methyl red]-lys-[n-(6-aminohexyl)-gly]8-n2-(6-aminohexyl)-gly-nh2 homo sapiens 0.015 0.015 1 PMID:27168077 -3.4.22.56 n-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-asp-gly-pro-asp-6-aminohexanoyl-n6-[methyl red]-lys-[n-(6-aminohexyl)-gly]8-n2-(6-aminohexyl)-gly-nh2 homo sapiens 0.00917 0.00917 1 PMID:27168077 -3.4.22.56 n-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-asp-gly-val-asp-6-aminohexanoyl-n6-[methyl red]-lys-[n-(6-aminohexyl)-gly]8-n2-(6-aminohexyl)-gly-nh2 homo sapiens 0.0083 0.0083 1 PMID:27168077 -3.4.22.56 n-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-asp-leu-pro-asp-6-aminohexanoyl-n6-[methyl red]-lys-[n-(6-aminohexyl)-gly]8-n2-(6-aminohexyl)-gly-nh2 homo sapiens 0.023 0.023 1 PMID:27168077 -3.4.22.56 n-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-asp-leu-val-asp-6-aminohexanoyl-n6-[methyl red]-lys-[n-(6-aminohexyl)-gly]8-n2-(6-aminohexyl)-gly-nh2 homo sapiens 0.015 0.015 1 PMID:27168077 -3.4.22.56 n-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-asp-val-pro-asp-6-aminohexanoyl-n6-[methyl red]-lys-[n-(6-aminohexyl)-gly]8-n2-(6-aminohexyl)-gly-nh2 homo sapiens 0.028 0.028 1 PMID:27168077 -3.4.22.56 n-(5(6)-carboxyfluoresceinyl)-6-aminohexanoyl-asp-val-val-asp-6-aminohexanoyl-n6-[methyl red]-lys-[n-(6-aminohexyl)-gly]8-n2-(6-aminohexyl)-gly-nh2 homo sapiens 0.023 0.023 1 PMID:27168077 -3.4.22.57 acetyl-fead-7-amido-4-methylcoumarin ancestral carnivora reconstruction 0.58 0.58 1 PMID:35427646 -3.4.22.57 acetyl-fead-7-amido-4-methylcoumarin canis lupus familiaris 1.22 1.22 1 PMID:35427646 -3.4.22.57 acetyl-wehd 7-amido-4-methylcoumarin homo sapiens 1.2 1.2 1 PMID:10381624 -3.4.22.57 acetyl-wehd-7-amido-4-methylcoumarin ancestral carnivora reconstruction 9.2 9.2 1 PMID:35427646 -3.4.22.57 acetyl-wehd-7-amido-4-methylcoumarin canis lupus familiaris 8.87 8.87 1 PMID:35427646 -3.4.22.57 acetyl-wqpd-7-amido-4-methylcoumarin ancestral carnivora reconstruction 1.53 1.53 1 PMID:35427646 -3.4.22.57 acetyl-wqpd-7-amido-4-methylcoumarin canis lupus familiaris 2.96 2.96 1 PMID:35427646 -3.4.22.57 acetyl-yvad-amido-4-methylcoumarin homo sapiens 0.5 0.5 1 PMID:9054418 -3.4.22.57 llsdgid canis lupus familiaris 4.93 4.93 1 PMID:35427646 -3.4.22.57 lsdgide canis lupus familiaris 0.3 0.3 1 PMID:35427646 -3.4.22.57 sdgidee canis lupus familiaris 0.02 0.02 1 PMID:35427646 -3.4.22.57 sllsdg canis lupus familiaris 1.06 1.06 1 PMID:35427646 -3.4.22.57 sllsdgi canis lupus familiaris 3.75 3.75 1 PMID:35427646 -3.4.22.57 sllsdgid canis lupus familiaris 2.23 2.23 1 PMID:35427646 -3.4.22.57 sllsdgide canis lupus familiaris 3.0 3.0 1 PMID:35427646 -3.4.22.57 sllsdgidee canis lupus familiaris 2.72 2.72 1 PMID:35427646 -3.4.22.57 succinyl-yvad-4-nitroanilide homo sapiens 1.1 1.085 2 PMID:9054418;PMID:9578463 -3.4.22.57 succinyl-yvad-amido-4-methylcoumarin homo sapiens 0.4 0.4 1 PMID:9578463 -3.4.22.58 acetyl-wehd-7-amido-4-methylcoumarin homo sapiens 2.3 2.3 1 PMID:10381624 -3.4.22.59 ac-val-glu-ile-asp-7-amido-4-trifluoromethylcoumarin homo sapiens 2.27 2.27 1 PMID:30940883 -3.4.22.59 n-acetyl-asp-glu-val-asp-7-amido-4-methylcoumarin homo sapiens 5.5 5.5 1 PMID:19694615 -3.4.22.59 n-acetyl-asp-glu-val-asp-7-amido-4-trifluoromethylcoumarin homo sapiens 3.2 3.2 1 PMID:19694615 -3.4.22.59 n-acetyl-ile-val-leu-asp-7-amido-4-methylcoumarin homo sapiens 1.0 1.0 1 PMID:19694615 -3.4.22.59 n-acetyl-thr-glu-val-asp-7-amido-4-methylcoumarin homo sapiens 6.0 6.0 1 PMID:19694615 -3.4.22.59 n-acetyl-val-glu-his-asp-7-amido-4-methylcoumarin homo sapiens 43.0 43.0 1 PMID:19694615 -3.4.22.59 n-acetyl-val-glu-ile-asp-7-amido-4-methylcoumarin homo sapiens 3.6 2.595 2 PMID:19694615;PMID:30420425 -3.4.22.59 n-acetyl-veid-7-amido-4-methylcoumarin homo sapiens 0.7 0.7 1 PMID:22891250 -3.4.22.6 benzoyl-arg-4-nitroanilide carica papaya 0.05 0.026500000000000003 2 PMID:3513753 -3.4.22.6 benzyloxycarbonyl-lys phenyl ester carica papaya 15.5 14.75 2 PMID:3513753 -3.4.22.6 benzyloxycarbonyl-phe-arg-4-methylcoumarin 7-amide carica papaya 2.9 2.9 1 PMID:3919769 -3.4.22.6 methyl red-abu-ala-pro-val-lys-lys(n5-(5-carboxyfluorescein))-nh2 carica papaya 590.0 418.0 2 PMID:18814838 -3.4.22.6 methyl red-abu-ser-ala-pro-val-lys-ala-lys(n6-(5-carboxyfluorescein))-nh2 carica papaya 360.0 246.5 2 PMID:18814838 -3.4.22.6 succinyl-albumin carica papaya 4.0 4.0 1 PMID:3919769 -3.4.22.60 ac-devd-7-amido-4-methylcoumarin homo sapiens 2.4 1.65 2 PMID:27032039 -3.4.22.60 ac-dvad-p-nitroanilide homo sapiens 6.08 3.51335 2 PMID:16781734 -3.4.22.60 ac-ldvad-p-nitroanilide homo sapiens 6.08 3.591 2 PMID:16781734 -3.4.22.60 ac-vdvad-p-nitroanilide homo sapiens 1.26 1.26 1 PMID:16781734 -3.4.22.60 ac-veid-7-amido-4-methylcoumarin homo sapiens 0.1 0.1 1 PMID:27032039 -3.4.22.60 acetyl-devd-7-amido-4-fluoromethylcoumarin homo sapiens 6.9 6.9 1 PMID:12824163 -3.4.22.60 acetyl-devd-7-amido-4-methylcoumarin homo sapiens 6.3 5.9 2 PMID:10381624 -3.4.22.60 acetyl-devd-p-nitroanilide homo sapiens 10.3 10.3 1 PMID:12824163 -3.4.22.60 n-acetyl-asp-glu-val-asp-p-nitroanilide homo sapiens 3.6 3.6 1 PMID:19782754 -3.4.22.60 n-acetyl-devd-7-amido-4-fluoromethylcoumarin homo sapiens 3.4 3.4 1 PMID:22451931 -3.4.22.60 n-acetyl-devd-7-amido-4-trifluoromethylcoumarin homo sapiens 5.6 5.6 1 PMID:28863261 -3.4.22.60 n-acetyl-pevd-7-amido-4-trifluoromethylcoumarin homo sapiens 0.9 0.9 1 PMID:28863261 -3.4.22.61 acetyl-devd-7-amido-4-methylcoumarin homo sapiens 0.37 0.37 1 PMID:10381624 -3.4.22.61 acetyl-ietd-7-amido-4-fluoromethylcoumarin homo sapiens 1.25 0.88 4 PMID:15209560 -3.4.22.62 acetyl-vehd-7-amido-4-methylcoumarin homo sapiens 0.2 0.15000000000000002 2 PMID:10381624 -3.4.22.65 2-aminobenzoic acid-val-ala-nle-ser-(3-nitro)-tyrosinyl-aspartamide dermatophagoides pteronyssinus 0.2 0.2 1 PMID:10848897 -3.4.22.69 (ala-arg-leu-gln-nh)2-rhodamine severe acute respiratory syndrome-related coronavirus 0.0153 0.0153 1 PMID:16647061 -3.4.22.69 2-aminobenzoyl-tsavlqsgfrk-2,4-dinitrophenyl amide severe acute respiratory syndrome-related coronavirus 0.032 0.032 1 PMID:18275836 -3.4.22.69 [4-(4-dimethylaminophenylazo)benzoic acid]-knstlqsglrke-[5-[2'-(aminoethyl)amino]-naphthalenesulfonic acid] severe acute respiratory syndrome-related coronavirus 0.16 0.16 1 PMID:17046271 -3.4.22.69 [4-(4-dimethylaminophenylazo)benzoic acid]-ktsavlqsgfrkme-5-[2'-(aminoethyl)amino]-naphthalenesulfonic acid severe acute respiratory syndrome-related coronavirus 1.5 1.5 1 PMID:18237196 -3.4.22.69 abz-lqsgfrk(dnp)nh2 severe acute respiratory syndrome-related coronavirus 0.02 0.0115 2 PMID:21087086 -3.4.22.69 abz-lyqppqtsitsavlqsgfrk(dnp)nh2 severe acute respiratory syndrome-related coronavirus 0.28 0.28 1 PMID:21087086 -3.4.22.69 abz-qtsitsavlqsgfrk(dnp)nh2 severe acute respiratory syndrome-related coronavirus 0.6 0.6 1 PMID:21087086 -3.4.22.69 abz-savlqsgfrk(dnp)nh2 severe acute respiratory syndrome-related coronavirus 3.3 1.6849999999999998 2 PMID:21087086 -3.4.22.69 abz-savlqsgfrkmafpsgk(dnp)nh2 severe acute respiratory syndrome-related coronavirus 2.9 2.9 1 PMID:21087086 -3.4.22.69 abz-savlqsgfrkmak(dnp)nh2 severe acute respiratory syndrome-related coronavirus 3.0 3.0 1 PMID:21087086 -3.4.22.69 abz-savlqsgk(dnp)nh2 severe acute respiratory syndrome-related coronavirus 0.11 0.057 2 PMID:21087086 -3.4.22.69 abz-sgadvlyqppqtsitsavlqsgfrk(dnp)nh2 severe acute respiratory syndrome-related coronavirus 0.38 0.38 1 PMID:21087086 -3.4.22.69 abz-vlqsgfrk(dnp)nh2 severe acute respiratory syndrome-related coronavirus 0.77 0.405 2 PMID:21087086 -3.4.22.69 atvrlqagnat severe acute respiratory syndrome-related coronavirus 3.29 3.29 1 PMID:14561748 -3.4.22.69 dabcyl-ktsavlqsgfrkme-edans severe acute respiratory syndrome coronavirus 2 0.0014 0.0014 1 PMID:35079088 -3.4.22.69 dabcyl-tsavlqsgfrkme-edans severe acute respiratory syndrome coronavirus 2 5.38 5.38 1 PMID:33454058 -3.4.22.69 dabcyl-tsavlqsgfrkme-edans severe acute respiratory syndrome-related coronavirus 2.88 2.88 1 PMID:33454058 -3.4.22.69 fypklqasqaw severe acute respiratory syndrome-related coronavirus 1.57 1.57 1 PMID:14561748 -3.4.22.69 n-methylanthranilyl-tsavlqsgfrk(2,4-dinitrophenyl) severe acute respiratory syndrome-related coronavirus 0.37 0.37 1 PMID:27799534 -3.4.22.69 o-aminobenzoyl-tsavlqsgfry(no2)g severe acute respiratory syndrome-related coronavirus 0.38 0.38 1 PMID:16895476 -3.4.22.69 phtvlqavgac severe acute respiratory syndrome-related coronavirus 1.68 1.68 1 PMID:14561748 -3.4.22.69 savlqmgfrk severe acute respiratory syndrome-related coronavirus 1.6 1.6 1 PMID:20041855 -3.4.22.69 ser-ala-val-leu-gln-met-gly-phe-arg-lys severe acute respiratory syndrome-related coronavirus 0.027 0.027 1 PMID:20041855 -3.4.22.69 sgvtfqgkfkk severe acute respiratory syndrome-related coronavirus 2.55 2.55 1 PMID:14561748 -3.4.22.69 sitsavlq-p-nitroanilide severe acute respiratory syndrome-related coronavirus 0.86 0.86 1 PMID:18237196 -3.4.22.69 sitsavlq-p-nitrophenyl ester severe acute respiratory syndrome-related coronavirus 0.6 0.6 1 PMID:18237196 -3.4.22.69 sitsavlqsgfrkma severe acute respiratory syndrome-related coronavirus 8.5 8.5 1 PMID:18237196 -3.4.22.69 tftrlqslenv severe acute respiratory syndrome-related coronavirus 0.847 0.847 1 PMID:14561748 -3.4.22.69 thr-ser-ala-val-leu-gln-4-nitroanilide severe acute respiratory syndrome-related coronavirus 0.11 0.11 1 PMID:26879383 -3.4.22.69 thr-ser-ala-val-leu-gln-p-nitroanilide severe acute respiratory syndrome-related coronavirus 0.63 0.63 1 PMID:20371333 -3.4.22.69 tsavlqsgfrk-nh2 severe acute respiratory syndrome-related coronavirus 12.2 12.2 1 PMID:14561748 -3.4.22.7 n-alpha-benzyloxycarbonyl-l-gln-4-nitrophenyl ester asclepias curassavica 121.5 121.5 1 PMID:19204833 -3.4.22.7 n-carbobenzoxy-lys p-nitrophenyl ester asclepias syriaca 59.6 44.55 10 PMID:6988008 -3.4.22.7 nalpha-cbz-l-gln-4-nitrophenyl ester asclepias curassavica 121.5 121.5 1 PMID:19204833 -3.4.22.70 abz-lpetg-dap(dnp) staphylococcus aureus 0.3 0.3 1 PMID:15247224 -3.4.22.70 abz-lpetg-dap(dnp)-nh2 staphylococcus aureus 0.27 0.27 1 PMID:14769334 -3.4.22.70 aminobenzoyl-lpetgg-diaminopropionic acid(dinitrophenol)-nh2 staphylococcus aureus 1.1 1.1 1 PMID:18375951 -3.4.22.70 dabsyl-llktgvas-edans lactococcus lactis subsp. lactis 1.0 1.0 1 PMID:35654243 -3.4.22.70 dabsyl-lpfaggag-edans lactococcus lactis subsp. lactis 0.01 0.01 1 PMID:35654243 -3.4.22.70 dabsyl-lpftggqg-edans lactococcus lactis subsp. lactis 0.013 0.013 1 PMID:35654243 -3.4.22.70 dnp-aqalpetgee-nh2 staphylococcus aureus 0.013 0.013 1 PMID:14769030 -3.4.22.70 gly-gly-gly staphylococcus aureus 0.18 0.18 1 PMID:17107653 -3.4.22.70 n-(2-aminobenzoyl)-l-leucyl-l-prolyl-l-alpha-glutamyl-l-threonylglycyl-3-(2,4-dinitroanilino)-l-alaninamide staphylococcus aureus 0.69 0.69 1 PMID:17518446 -3.4.22.70 o-aminobenzoyl-lpetg-2,4-dinitrophenyl bacillus anthracis 8.3e-06 7.5e-06 2 PMID:20489200 -3.4.22.8 ac-l-lys-4-nitroanilide clostridium perfringens 22.53 22.53 1 PMID:19850615 -3.4.22.8 alpha-benzoyl-arg ethyl ester hathewaya histolytica 643.0 580.0 3 PMID:5126938;PMID:762145;PMID:927173 -3.4.22.8 benzoyl-arg ethyl ester hathewaya histolytica 1170.0 1170.0 1 PMID:8192862 -3.4.22.8 benzoyl-l-arg-4-nitroanilide clostridium perfringens 109.3 109.3 1 PMID:19850615 -3.4.22.8 maleyl-tyr-arg ethyl ester hathewaya histolytica 824.0 824.0 1 PMID:8192862 -3.4.22.8 n-benzoyl-l-arg amide hathewaya histolytica 87.0 87.0 1 PMID:5126938 -3.4.22.8 nalpha-benzoyl-l-arginine-4-nitroanilide hathewaya histolytica 69.5 54.15 2 PMID:20940055 -3.4.22.8 nalpha-benzoyl-l-lys methyl ester hathewaya histolytica 22.0 22.0 1 PMID:5126938 -3.4.22.8 nalpha-p-tosyl-l-arg amide hathewaya histolytica 10.0 10.0 1 PMID:5126938 -3.4.22.8 nalpha-p-tosyl-l-arg methyl ester hathewaya histolytica 9.8 9.8 1 PMID:5126938 -3.4.22.8 p-nitrophenyl p-guanidinobenzoate hathewaya histolytica 31.0 31.0 1 PMID:5126938 -3.4.22.8 p-toluenesulfonyl-l-arg methyl ester hathewaya histolytica 86.0 86.0 1 PMID:5126938 -3.4.23.1 ((7-methoxycoumarin-4-yl)acetyl)-lys-lys-pro-ala-glu-phe-phe-ala-leu-lys-(2,4-dinitrophenyl) shewanella denitrificans 3.51 3.51 1 PMID:27029611 -3.4.23.1 acid-denatured hemoglobin oncorhynchus mykiss 19.1 8.37 3 * -3.4.23.1 afpleferel homo sapiens 8.9 8.9 1 PMID:19819898 -3.4.23.1 afpleferel sus scrofa 45.0 45.0 1 PMID:19819898 -3.4.23.1 afpleffrel homo sapiens 85.0 85.0 1 PMID:19819898 -3.4.23.1 afpleffrel sus scrofa 472.0 472.0 1 PMID:19819898 -3.4.23.1 afplefirel homo sapiens 56.0 56.0 1 PMID:19819898 -3.4.23.1 afplefirel sus scrofa 203.0 203.0 1 PMID:19819898 -3.4.23.1 benzyloxycarbonyl-gly-gly-phe-phe 3-(4-pyridyl)propyl ester sus scrofa 71.8 64.15 2 PMID:30064809 -3.4.23.1 benzyloxycarbonyl-gly-phe-phe 3-(4-pyridyl)propyl ester sus scrofa 3.1 2.6500000000000004 2 PMID:30064809 -3.4.23.1 benzyloxycarbonyl-his-phe-phe-nh2 sus scrofa 0.21 0.21 1 PMID:5340947 -3.4.23.1 benzyloxycarbonyl-his-phe-phe-o-ethyl ester sus scrofa 0.31 0.31 1 PMID:5340947 -3.4.23.1 benzyloxycarbonyl-his-phe-phe-o-methyl ester sus scrofa 0.15 0.15 1 PMID:5340947 -3.4.23.1 benzyloxycarbonyl-his-trp-phe-o-methyl ester sus scrofa 0.013 0.013 1 PMID:5340947 -3.4.23.1 benzyloxycarbonyl-his-tyr-phe-o-methyl ester sus scrofa 0.013 0.013 1 PMID:5340947 -3.4.23.1 benzyloxycarbonyl-phe-phe 3-(4-pyridyl)propyl ester sus scrofa 0.74 0.615 2 PMID:30064809 -3.4.23.1 benzyloxycarbonyl-phe-phe-oet sus scrofa 0.13 0.10500000000000001 4 PMID:30064809 -3.4.23.1 bovine serum albumin sus scrofa 4.44 4.44 1 PMID:30064809 -3.4.23.1 hemoglobin albatrossia pectoralis 50.0 50.0 1 PMID:17493857 -3.4.23.1 hemoglobin lateolabrax japonicus 7.34 7.34 1 PMID:21167955 -3.4.23.1 hemoglobin micropterus salmoides 62.9 57.8 2 PMID:25608034 -3.4.23.1 hemoglobin monopterus albus 23.2 23.2 1 PMID:21140210 -3.4.23.1 hemoglobin saurida micropectoralis 32.68 27.3 3 PMID:34274702 -3.4.23.1 kpaeff(no2)al sus scrofa 96.0 96.0 1 * -3.4.23.1 kpaeffrl micropterus salmoides 215.5 23.799999999999997 10 PMID:26627128 -3.4.23.1 kpaeffrl sus scrofa 75.9 21.9 5 PMID:26627128 -3.4.23.1 kpief(no2)rl sus scrofa 68.9 68.9 1 PMID:11106168 -3.4.23.1 kpikf(no2)rl sus scrofa 38.9 38.9 1 PMID:11106168 -3.4.23.1 kpilf(no2)rl sus scrofa 14.0 14.0 1 PMID:11106168 -3.4.23.1 kpiqf(no2)rl sus scrofa 47.9 24.0 2 PMID:11106168 -3.4.23.1 kppef(no2)rl sus scrofa 47.3 47.3 1 PMID:11106168 -3.4.23.1 l-lys-l-pro-l-ala-l-glu-l-phe-l-phe(no2)-l-ala-l-leu sus scrofa 162.0 162.0 1 PMID:14693908 -3.4.23.1 leu-ser-phe(p-no2)-nle-ala-leu sus scrofa 88.7 56.25 2 PMID:10861225 -3.4.23.1 lys-pro-ala-glu-phe-phe(no2)-ala-leu sus scrofa 56.0 56.0 1 PMID:19715777 -3.4.23.1 lys-pro-ala-glu-phe-phe(p-no2)-ala-leu sus scrofa 181.0 180.75 2 PMID:10861225 -3.4.23.1 mca-kkpaeffalk-dnp shewanella amazonensis 0.03 0.03 1 PMID:21749650 -3.4.23.1 n,n-dimethylcasein ovis aries 7.0 7.0 1 PMID:15546 -3.4.23.1 n,n-dimethylhemoglobin ovis aries 18.3 18.3 1 PMID:15546 -3.4.23.1 pomc (165-174) homo sapiens 2.7 2.7 1 PMID:19819898 -3.4.23.1 pomc (165-174) sus scrofa 3.7 3.7 1 PMID:19819898 -3.4.23.1 pro-thr-glu-phe-(p-nitro-phe)-arg-leu-oh trematomus bernacchii 3.32 1.93 2 PMID:17976195 -3.4.23.1 substance p micropterus salmoides 61.0 49.9 2 PMID:25608034 -3.4.23.15 angiotensinogen bos taurus 1.5 1.5 1 PMID:7042710 -3.4.23.15 angiotensinogen homo sapiens 1.35 0.775 2 PMID:30563843;PMID:3280035 -3.4.23.15 angiotensinogen rattus norvegicus 0.00867 0.00817 3 PMID:718949 -3.4.23.15 recombinant ovine angiotensinogen from cho cells homo sapiens 0.46 0.46 1 PMID:27052373 -3.4.23.15 recombinant ovine angiotensinogen from escherichia coli homo sapiens 0.59 0.59 1 PMID:27052373 -3.4.23.16 2-aminobenzoyl-ti-nle-phe(no2)-er human immunodeficiency virus 1 5.46 4.8 2 PMID:8943273 -3.4.23.16 2-aminobenzoyl-ti-nle-phe(no2)-qr human immunodeficiency virus 1 19.5 9.25 3 PMID:8943273 -3.4.23.16 2-aminobenzoyl-ti-nle-phe(no2)-qr-nh2 human immunodeficiency virus 1 7.4 7.4 1 PMID:11802730 -3.4.23.16 abz-thr-ile-nle-phe(no2)-gln-arg human immunodeficiency virus 1 3.2 3.2 1 PMID:18597780 -3.4.23.16 aetfyvdgaa human immunodeficiency virus 1 0.41 0.2054 2 PMID:11598128 -3.4.23.16 ctlnfpisp human immunodeficiency virus 1 1.72 0.885 2 PMID:11598128 -3.4.23.16 dtvieems human immunodeficiency virus 1 0.0483 0.0483 1 PMID:8068616 -3.4.23.16 dtvleems human immunodeficiency virus 1 4.35 4.35 1 PMID:8068616 -3.4.23.16 dtvveems human immunodeficiency virus 1 0.13 0.13 1 PMID:8068616 -3.4.23.16 gaetfyvdgaa human immunodeficiency virus 1 5.05 5.05 1 PMID:9315877 -3.4.23.16 ipfaaaqqrk human immunodeficiency virus 1 0.3 0.3 1 PMID:22238126 -3.4.23.16 irkilfldg human immunodeficiency virus 1 1.2 0.64 2 PMID:11598128 -3.4.23.16 karlmaealk human immunodeficiency virus 1 0.3 0.3 1 PMID:22238126 -3.4.23.16 karv-nle-phe(no2)-ea-nle human immunodeficiency virus 1 1.23 1.23 1 PMID:10429209 -3.4.23.16 karv-nle-phe(no2)-ea-nle-nh2 human immunodeficiency virus 1 3.74 2.8200000000000003 2 PMID:10467100;PMID:9188447 -3.4.23.16 karvlaeams human immunodeficiency virus 1 0.89 0.5 2 PMID:11598128 -3.4.23.16 klrpgnflqsrp human immunodeficiency virus 1 12.7 12.7 1 PMID:9315877;PMID:9561198 -3.4.23.16 lys-ala-arg-val-nle-phe(4-no2)-glu-ala-nle-gly human immunodeficiency virus 1 13.0 7.8 6 PMID:18092815 -3.4.23.16 lys-ala-arg-val-nle-phe(4-no2)-glu-ala-nle-nh2 human immunodeficiency virus 1 30.0 30.0 1 PMID:17977555 -3.4.23.16 pafvlaeamr human immunodeficiency virus 1 0.25 0.25 1 PMID:9753473 -3.4.23.16 pafvlmeamr human immunodeficiency virus 1 0.933 0.933 1 PMID:9753473 -3.4.23.16 parvlaeamr human immunodeficiency virus 1 0.267 0.267 1 PMID:9753473 -3.4.23.16 parvlfeamr human immunodeficiency virus 1 1.03 1.03 1 PMID:9753473 -3.4.23.16 parvlieamr human immunodeficiency virus 1 0.367 0.367 1 PMID:9753473 -3.4.23.16 parvlleamr human immunodeficiency virus 1 0.583 0.583 1 PMID:9753473 -3.4.23.16 parvlveamr human immunodeficiency virus 1 0.833 0.833 1 PMID:9753473 -3.4.23.16 pqitlwqrp human immunodeficiency virus 1 0.0967 0.0967 1 PMID:8068616 -3.4.23.16 reydqiiievs human immunodeficiency virus 1 0.025 0.025 1 PMID:8068616 -3.4.23.16 reydqilievs human immunodeficiency virus 1 2.85 2.85 1 PMID:8068616 -3.4.23.16 reydqilikvs human immunodeficiency virus 1 0.000833 0.000833 1 PMID:8068616 -3.4.23.16 rqgtvsfnfpqitl human immunodeficiency virus 1 62.7 62.7 1 PMID:9315877;PMID:9521105;PMID:9561198 -3.4.23.16 tatimmqrgn human immunodeficiency virus 1 58.8 58.8 1 PMID:9315877;PMID:9521105 -3.4.23.16 vlqnypivq human immunodeficiency virus 1 0.06 0.06 1 PMID:22238126 -3.4.23.16 vsqlypivq human immunodeficiency virus 1 0.4 0.4 1 PMID:22238126 -3.4.23.16 vsqnypiv human immunodeficiency virus 1 4.02 4.02 1 PMID:8068616 -3.4.23.16 vsqnypivq human immunodeficiency virus 1 51.8 51.8 1 PMID:9315877;PMID:9561198 -3.4.23.16 vsqvypivq human immunodeficiency virus 1 2.6 2.6 1 PMID:22238126 -3.4.23.16 vvqnypivq human immunodeficiency virus 1 0.16 0.16 1 PMID:22238126 -3.4.23.18 benzyloxycarbonyl-ala-ala-lys-ala-ala-ala aspergillus niger 30.5 19.91 2 PMID:4581238 -3.4.23.18 benzyloxycarbonyl-ala-lys-ala-ala-ala aspergillus niger 2.18 1.32 2 PMID:4581238 -3.4.23.18 benzyloxycarbonyl-lys-ala-ala-ala aspergillus niger 0.17 0.10700000000000001 2 PMID:4581238 -3.4.23.18 benzyloxycarbonyl-lys-leu-ala-ala aspergillus niger 0.67 0.525 2 PMID:4581238 -3.4.23.18 chymotrypsinogen aspergillus oryzae 1.14 1.14 1 PMID:239702 -3.4.23.18 trypsinogen aspergillus oryzae 11.3 11.3 1 PMID:239702 -3.4.23.19 rgffhtpra aspergillus niger 0.19 0.19 1 PMID:9561240 -3.4.23.19 rgfftpra aspergillus niger 0.48 0.48 1 PMID:9561240 -3.4.23.19 rgffytpra aspergillus niger 6.08 3.31 2 PMID:9561240 -3.4.23.19 rgfmtpra aspergillus niger 0.26 0.26 1 PMID:9561240 -3.4.23.2 hemoglobin albatrossia pectoralis 32.0 32.0 1 PMID:17493857 -3.4.23.2 hemoglobin boreogadus saida 9.27 9.27 1 * -3.4.23.2 kpaefarl canis lupus familiaris 3.4 3.4 1 PMID:17128981 -3.4.23.2 kpagfarl canis lupus familiaris 169.0 169.0 1 PMID:17128981 -3.4.23.2 kpggfarl canis lupus familiaris 134.0 134.0 1 PMID:17128981 -3.4.23.20 ac-ala-ala-ala-lys-(no2)phe-ala-ala-amide penicillium janthinellum 34.0 34.0 1 PMID:10850809 -3.4.23.20 ac-ala-ala-lys-(4-nitro)phe-ala-ala amide penicillium janthinellum 47.0 36.0 3 PMID:3541904;PMID:6424704 -3.4.23.20 ac-ala-ala-lys-(4-nitro)phe-ala-ala-ala amide penicillium janthinellum 45.0 45.0 1 PMID:3284578 -3.4.23.20 ac-ala-ala-lys-(no2)phe-ala-ala-amide penicillium janthinellum 40.0 40.0 1 PMID:10850809 -3.4.23.20 ac-ala-ala-lys-(no2)phe-ala-amide penicillium janthinellum 15.0 15.0 1 PMID:10850809 -3.4.23.20 ac-ala-ala-lys-(no2)phe-amide penicillium janthinellum 0.36 0.36 1 PMID:10850809 -3.4.23.20 ac-ala-lys-(4-nitro)phe amide penicillium janthinellum 0.021 0.021 1 PMID:3284578 -3.4.23.20 ac-ala-lys-(no2)phe-ala-ala-amide penicillium janthinellum 0.3 0.3 1 PMID:10850809 -3.4.23.20 ac-ala-lys-(no2)phe-ala-amide penicillium janthinellum 0.6 0.6 1 PMID:10850809 -3.4.23.20 ac-ala-lys-(no2)phe-amide penicillium janthinellum 0.003 0.003 1 PMID:10850809 -3.4.23.20 ac-lys 4-nitrophenyl amide penicillium janthinellum 0.01 0.01 1 PMID:6424704 -3.4.23.20 ac-lys-(4-nitro)phe amide penicillium janthinellum 0.026 0.026 1 PMID:3284578 -3.4.23.20 ac-lys-(no2)phe-ala-ala-amide penicillium janthinellum 0.29 0.29 1 PMID:10850809 -3.4.23.20 ac-lys-(no2)phe-ala-amide penicillium janthinellum 0.4 0.4 1 PMID:10850809 -3.4.23.20 bovine trypsinogen penicillium janthinellum 5.0 5.0 1 PMID:1012008 -3.4.23.20 leu-ser-(4-nitro)phe-nle-ala-leu methyl ester penicillium janthinellum 11.4 8.9 2 PMID:6424704 -3.4.23.20 pro-thr-glu-phe-(4-nitro)phe-arg-leu penicillium janthinellum 37.3 37.3 1 PMID:3541904 -3.4.23.20 trypsinogen penicillium janthinellum 420.0 420.0 1 * -3.4.23.21 kaief p-nitrophenylalanine-rl rhizopus sp. 46.0 25.5 2 PMID:11352473 -3.4.23.21 klief p-nitrophenylalanine-rl rhizopus sp. 38.0 21.5 2 PMID:11352473 -3.4.23.21 kpaef p-nitrophenylalanine-rl rhizopus sp. 22.0 21.5 2 PMID:11352473 -3.4.23.21 kpalf p-nitrophenylalanine-rl rhizopus sp. 13.0 11.0 2 PMID:11352473 -3.4.23.21 kpdef p-nitrophenylalanine-rl rhizopus sp. 8.0 5.5 2 PMID:11352473 -3.4.23.21 kpiaf p-nitrophenylalanine-rl rhizopus sp. 17.0 10.0 2 PMID:11352473 -3.4.23.21 kpidf p-nitrophenylalanine-rl rhizopus sp. 6.08 5.0 3 PMID:11352473 -3.4.23.21 kpief p-nitrophenylalanine-rl rhizopus sp. 41.0 23.5 2 PMID:11352473 -3.4.23.21 kpilf p-nitrophenylalanine-rl rhizopus sp. 3.0 1.615 2 PMID:11352473 -3.4.23.21 kpisf p-nitrophenylalanine-rl rhizopus sp. 4.0 3.5 2 PMID:11352473 -3.4.23.21 kplef p-nitrophenylalanine-rl rhizopus sp. 7.0 7.0 1 PMID:11352473 -3.4.23.21 kpref p-nitrophenylalanine-rl rhizopus sp. 18.0 18.0 1 PMID:11352473 -3.4.23.21 kpsef p-nitrophenylalanine-rl rhizopus sp. 7.0 6.5 2 PMID:11352473 -3.4.23.21 kpvsy(4-no2-f)rl rhizopus microsporus var. chinensis 55.0 55.0 1 * -3.4.23.21 kpvsy(no2)frl rhizopus sp. 55.0 55.0 1 PMID:10419816 -3.4.23.21 ksief p-nitrophenylalanine-rl rhizopus sp. 13.0 7.4 2 PMID:11352473 -3.4.23.23 2-aminobenzoyl-klrmskq-n1-(2,4-dinitrophenyl)ethane-1,2-diamine rhizomucor miehei 0.5 0.5 1 PMID:27165660 -3.4.23.23 2-aminobenzoyl-klrskkq-n1-(2,4-dinitrophenyl)ethane-1,2-diamine rhizomucor miehei 1.1 1.1 1 PMID:27165660 -3.4.23.23 2-aminobenzoyl-klrsskq-n1-(2,4-dinitrophenyl)ethane-1,2-diamine rhizomucor miehei 0.35 0.35 1 PMID:27165660 -3.4.23.23 2-aminobenzoyl-klrssmq-n1-(2,4-dinitrophenyl)ethane-1,2-diamine rhizomucor miehei 0.045 0.045 1 PMID:27165660 -3.4.23.23 2-aminobenzoyl-klrswkq-n1-(2,4-dinitrophenyl)ethane-1,2-diamine rhizomucor miehei 0.12 0.12 1 PMID:27165660 -3.4.23.23 2-aminobenzoyl-klrwskq-n1-(2,4-dinitrophenyl)ethane-1,2-diamine rhizomucor miehei 0.15 0.15 1 PMID:27165660 -3.4.23.23 pro-thr-glu-phe-(4-nitro)phe-arg-leu rhizomucor miehei 16.0 10.5 2 PMID:3541904 -3.4.23.24 4-(4-dimethylaminophenylazo)benzyl-glu-his-val-lys-leu-val-glu-5-(2-aminoethylamino)-1-naphthalenesulfonic acid candida parapsilosis 48.7 31.950000000000003 2 PMID:19166319 -3.4.23.24 ala-thr-his-gln-val-tyr-4-nitrophenylalanine-val-arg-lys-ala candida parapsilosis 1.41 1.41 1 PMID:16201875 -3.4.23.24 lys-pro-ala-glu-phe-4-nitrophenylalanine-ala-leu candida parapsilosis 31.8 31.8 1 PMID:16201875 -3.4.23.24 lys-pro-leu-glu-met-4-nitrophenylalanine-ala-leu candida parapsilosis 24.11 24.11 1 PMID:16201875 -3.4.23.25 (7-methoxycoumarin-4-yl)acetyl-apakffrlk(2,4-dinitrophenyl)-nh2 saccharomyces cerevisiae 18.1 18.1 1 PMID:9644256 -3.4.23.25 ala-leu-ser-ala-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 10.9 10.9 1 PMID:9644256 -3.4.23.25 ala-pro-ala-lys-phe-(no2)-phe-arg-leu saccharomyces cerevisiae 14.4 7.206 2 PMID:9644256 -3.4.23.25 ala-ser-ala-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 14.4 14.4 1 PMID:9644256 -3.4.23.25 arg-ser-ala-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 14.7 14.7 1 PMID:9644256 -3.4.23.25 asp-ser-ala-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 18.6 18.6 1 PMID:9644256 -3.4.23.25 gly-ala-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 19.7 19.7 1 PMID:9644256 -3.4.23.25 leu-ser-ala-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 13.8 13.8 1 PMID:9644256 -3.4.23.25 lys-ala-ala-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 6.7 6.7 1 PMID:9644256 -3.4.23.25 lys-arg-ala-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 5.8 5.8 1 PMID:9644256 -3.4.23.25 lys-asp-ala-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 2.4 2.4 1 PMID:9644256 -3.4.23.25 lys-leu-ala-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 3.5 3.5 1 PMID:9644256 -3.4.23.25 lys-pro-ala-ala-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 15.9 15.9 1 PMID:9644256 -3.4.23.25 lys-pro-ala-arg-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 9.4 9.4 1 PMID:9644256 -3.4.23.25 lys-pro-ala-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 1.7 1.7 1 PMID:9644256 -3.4.23.25 lys-pro-ala-leu-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 8.4 8.4 1 PMID:9644256 -3.4.23.25 lys-pro-ala-lys-phe-4-(no2)phe-ala -leu saccharomyces cerevisiae 1.5 1.5 1 PMID:9644256 -3.4.23.25 lys-pro-ala-lys-phe-4-(no2)phe-arg-ala saccharomyces cerevisiae 6.7 6.7 1 PMID:9644256 -3.4.23.25 lys-pro-ala-lys-phe-4-(no2)phe-arg-arg saccharomyces cerevisiae 2.7 2.7 1 PMID:9644256 -3.4.23.25 lys-pro-ala-lys-phe-4-(no2)phe-arg-asp saccharomyces cerevisiae 1.7 1.7 1 PMID:9644256 -3.4.23.25 lys-pro-ala-lys-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 4.0 4.0 1 PMID:9644256 -3.4.23.25 lys-pro-ala-lys-phe-4-(no2)phe-arg-ser saccharomyces cerevisiae 4.7 4.7 1 PMID:9644256 -3.4.23.25 lys-pro-ala-lys-phe-4-(no2)phe-asp-leu saccharomyces cerevisiae 2.0 2.0 1 PMID:9644256 -3.4.23.25 lys-pro-ala-lys-phe-4-(no2)phe-leu-leu saccharomyces cerevisiae 1.7 1.7 1 PMID:9644256 -3.4.23.25 lys-pro-ala-lys-phe-4-(no2)phe-ser-leu saccharomyces cerevisiae 0.9 0.9 1 PMID:9644256 -3.4.23.25 lys-pro-ala-ser-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 6.7 6.7 1 PMID:9644256 -3.4.23.25 lys-pro-arg-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 3.3 3.3 1 PMID:9644256 -3.4.23.25 lys-pro-asp-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 1.9 1.9 1 PMID:9644256 -3.4.23.25 lys-pro-ile-glu-phe-l-nitrophenylalanine-arg-leu saccharomyces cerevisiae 44.0 44.0 1 PMID:17145748 -3.4.23.25 lys-pro-leu-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 10.6 10.6 1 PMID:9644256 -3.4.23.25 lys-ser-ala-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 10.4 10.4 1 PMID:9644256 -3.4.23.25 ser-ser-ala-asp-phe-4-(no2)phe-arg-leu saccharomyces cerevisiae 6.6 6.6 1 PMID:9644256 -3.4.23.25 suc-apakffrl-4-methylcoumarin 7-amide saccharomyces cerevisiae 18.5 18.5 1 PMID:9644256 -3.4.23.25 succinyl-lfaevayd-7-amido-4-methylcoumarin saccharomyces cerevisiae 3.73 3.4299999999999997 2 PMID:9644256 -3.4.23.25 succinyl-rffhllvy-7-amido-4-methylcoumarin saccharomyces cerevisiae 8.25 8.25 1 PMID:9644256 -3.4.23.3 acetyl-ala-phe-leu-val-his-nh2 homo sapiens 0.3 0.3 1 PMID:383072 -3.4.23.3 acetyl-ala-phe-leu-val-his-nh2 sus scrofa 7.01 7.01 1 PMID:383072;PMID:38772 -3.4.23.3 acetyl-phe-leu-val-his methyl ester sus scrofa 5.13 5.13 1 PMID:38772 -3.4.23.3 acetyl-phe-leu-val-his-nh2 homo sapiens 0.6 0.6 1 PMID:383072 -3.4.23.3 acetyl-phe-leu-val-his-nh2 sus scrofa 6.12 6.12 1 PMID:383072;PMID:38772 -3.4.23.3 acetyl-tyr-leu-val-his methyl ester sus scrofa 5.76 3.41 2 PMID:38772 -3.4.23.3 acetyl-tyr-leu-val-his-nh2 sus scrofa 4.45 1.08 3 PMID:38772 -3.4.23.3 pro-thr-glu-phe-(no2)phe-arg-leu sus scrofa 55.0 55.0 1 PMID:3937752 -3.4.23.32 d-2,3-diaminopropionic acid(n-methylanthraniloyl)-gfkffalrk(2,4-dinitrophenol) scytalidium lignicola 34.8 34.8 1 PMID:16895471 -3.4.23.34 (7-methoxycoumarin-4-yl)-acetyl-gly-lys-pro-ile-ile-phe-phe-arg-leu-lys(2,4-dinitrophenyl)-d-arg-nh2 rattus norvegicus 11.9 11.9 1 PMID:12204120 -3.4.23.34 (7-methoxycoumarin-4-yl)acetyl-gly-lys-pro-ile-ile-phe-phe-arg-leu-lys(dnp)-d-arg-nh2 rattus norvegicus 39.1 39.1 1 PMID:15843176 -3.4.23.34 (7-methoxycoumarin-4-yl)acetyl-gly-lys-pro-ile-leu-phe-phe-arg-leu-lys(dnp)-d-arg-nh2 rattus norvegicus 32.2 32.2 1 PMID:16272574 -3.4.23.34 (7-methoxycoumarin-4-yl)acetyl-gly-ser-pro-ala-phe-leu-ala-lys(dnp)-d-arg-nh2 homo sapiens 19.4 19.4 1 PMID:15843176 -3.4.23.34 (7-methoxycoumarin-4-yl)acetyl-gly-ser-pro-ala-phe-leu-ala-lys(dnp)-d-arg-nh2 rattus norvegicus 20.1 16.19 4 PMID:15843176;PMID:16272574 -3.4.23.34 (7-methoxycoumarin-4-yl)acetyl-gly-ser-ser-ala-phe-leu-ala-phe-lys(dnp)-d-arg-nh2 rattus norvegicus 1.68 1.68 1 PMID:15843176 -3.4.23.34 (7-methoxycoumarin-4-yl)acetyl-l-ala-gly-l-phe-l-ser-l-leu-l-pro-l-ala-l-lys(dnp)-d-arg-amide homo sapiens 322.5 322.5 1 PMID:20600629 -3.4.23.34 [his10]-substance p cavia porcellus 23.0 23.0 1 PMID:7545776 -3.4.23.34 [tyr8]-substance p cavia porcellus 40.0 40.0 1 PMID:7545776 -3.4.23.34 acetyl-substance p cavia porcellus 26.0 26.0 1 PMID:7545776 -3.4.23.34 acetyl-substance p(2-11) cavia porcellus 19.0 19.0 1 PMID:7545776 -3.4.23.34 acetyl-substance p(3-11) cavia porcellus 58.0 58.0 1 PMID:7545776 -3.4.23.34 acidic fibroblast growth factor cavia porcellus 18.0 18.0 1 PMID:7545776 -3.4.23.34 arg-modified substance p cavia porcellus 64.0 64.0 1 PMID:7545776 -3.4.23.34 big et-1 cavia porcellus 0.13 0.13 1 PMID:7545776 -3.4.23.34 big et-1 homo sapiens 0.13 0.13 1 PMID:1599425 -3.4.23.34 big et-2 homo sapiens 0.1 0.1 1 PMID:1599425 -3.4.23.34 big et-3 homo sapiens 0.14 0.14 1 PMID:1599425 -3.4.23.34 eledoisin cavia porcellus 10.0 10.0 1 PMID:7545776 -3.4.23.34 lys-pro-ala-glu-phe-(4-nitro)phe-arg-leu cavia porcellus 135.0 135.0 1 PMID:7545776 -3.4.23.34 lys-pro-ile-glu-phe-(4-nitro)phe-arg-leu cavia porcellus 170.0 170.0 1 PMID:7545776 -3.4.23.34 lys-pro-ile-glu-phe-(4-nitro)phe-arg-leu homo sapiens 115.0 72.0 7 PMID:2917642;PMID:8325357 -3.4.23.34 mocac-gly-lys-pro-ile-leu-phe-phe-arg-leu-lys(dnp)-d-arg-nh2 homo sapiens 360.0 360.0 1 PMID:15294281 -3.4.23.34 neurokinin a cavia porcellus 42.0 42.0 1 PMID:7545776 -3.4.23.34 porcine renin substrate cavia porcellus 13.0 13.0 1 PMID:7545776 -3.4.23.34 pro-pro-thr-ile-phe-(4-nitro)phe-arg-leu cavia porcellus 75.0 47.0 3 PMID:7545776 -3.4.23.34 pro-pro-thr-ile-phe-(4-nitro)phe-arg-leu homo sapiens 132.0 36.0 9 PMID:2917642;PMID:8325357 -3.4.23.34 pro-thr-glu-phe-(4-nitro)phe-arg-leu cavia porcellus 27.0 27.0 1 PMID:7545776 -3.4.23.34 substance p(2-11) cavia porcellus 22.0 22.0 1 PMID:7545776 -3.4.23.34 substance p(3-11) cavia porcellus 70.0 70.0 1 PMID:7545776 -3.4.23.34 substance p(4-11) cavia porcellus 0.74 0.74 1 PMID:7545776 -3.4.23.38 4-[[4'-(dimethylamino)phenyl]azo]-benzoyl-glu-arg-met-phe-leu-ser-phe-pro-(gamma-aminobutyryl)-5-[(2'-aminoethyl)-amino]naphthalenesulfonic acid plasmodium falciparum 0.473 0.473 1 PMID:12189138 -3.4.23.38 leu-glu-arg-ile-phe-phe(no2)-ser-phe plasmodium falciparum 16.0 2.1 3 PMID:10431809;PMID:9119023;PMID:9561249 -3.4.23.38 leu-glu-arg-val-phe-phe(no2)-ser-phe plasmodium falciparum 1.6 1.6 1 PMID:9119023;PMID:9561249 -3.4.23.38 lys-glu-leu-val-phe-phe(no2)-ala-leu-lys plasmodium falciparum 10.0 10.0 1 PMID:10431809 -3.4.23.38 lys-glu-phe-asn-phe-phe(no2)-ala-leu-lys plasmodium falciparum 12.0 7.0 2 PMID:10431809 -3.4.23.38 lys-glu-phe-val-phe-phe(no2)-ala-leu-lys plasmodium falciparum 18.0 10.75 2 PMID:10431809 -3.4.23.38 lys-glu-phe-val-phe-phe(no2)-arg-leu-lys plasmodium falciparum 10.0 5.8 2 PMID:10431809 -3.4.23.39 4-(4-dimethylaminophenylazo)benzoyl-ch2-ch2-co-co-alermflsfp-diaminopimelate-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid plasmodium falciparum 2.52 2.425 2 PMID:15574427 -3.4.23.39 4-(4-dimethylaminophenylazo)benzoyl-ch2-ch2-co-ermflsfp-diaminopimelate-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid plasmodium falciparum 1.1 0.9875 2 PMID:15574427 -3.4.23.39 4-[[4'-(dimethylamino)phenyl]azo]-benzoyl-glu-arg-met-phe-leu-ser-phe-pro-(gamma-aminobutyryl)-5-[(2'-aminoethyl)-amino]naphthalenesulfonic acid plasmodium falciparum 2.31 2.31 1 PMID:12189138 -3.4.23.39 ala-leu-glu-arg-thr-phe-phe(no2)-ser-phe-pro-thr plasmodium falciparum 6.0 4.9 2 PMID:7925966;PMID:9561249 -3.4.23.39 edans-co-ch2-ch2-co-ala-leu-glu-arg-met-phe-leu-ser-phe-pro-dap-(dabcyl)-oh plasmodium falciparum 2.1 1.11 3 PMID:19910416 -3.4.23.39 leu-glu-arg-ile-phe-phe(no2)-ser-phe plasmodium falciparum 15.0 13.0 3 PMID:10431809;PMID:9561249 -3.4.23.39 leu-glu-arg-val-phe-phe(no2)-ser-phe plasmodium falciparum 9.0 9.0 1 PMID:9561249 -3.4.23.39 leu-ser-phe(no2)-nle-ala-leu-ome plasmodium falciparum 10.4 10.4 1 PMID:18471091 -3.4.23.39 lys-ala-ile-glu-phe-phe(no2)-arg-leu plasmodium falciparum 2.0 2.0 1 PMID:10548045 -3.4.23.39 lys-asp-ile-glu-phe-phe(no2)-arg-leu plasmodium falciparum 1.1 1.1 1 PMID:10548045 -3.4.23.39 lys-glu-leu-val-phe-phe(no2)-ala-leu-lys plasmodium falciparum 6.0 3.75 2 PMID:10431809 -3.4.23.39 lys-glu-phe-asn-phe-phe(no2)-ala-leu-lys plasmodium falciparum 7.0 7.0 1 PMID:10431809 -3.4.23.39 lys-glu-phe-ile-phe-phe(no2)-ala-leu-lys plasmodium falciparum 15.2 15.2 1 PMID:9119023 -3.4.23.39 lys-glu-phe-val-phe-phe(no2)-ala-leu-lys plasmodium falciparum 19.0 17.0 3 PMID:10431809;PMID:9119023 -3.4.23.39 lys-glu-phe-val-phe-phe(no2)-arg-leu-lys plasmodium falciparum 11.0 11.0 1 PMID:10431809 -3.4.23.39 lys-lys-ile-glu-phe-phe(no2)-arg-leu plasmodium falciparum 0.17 0.17 1 PMID:10548045 -3.4.23.39 lys-phe-ile-glu-phe-phe(no2)-arg-leu plasmodium falciparum 1.1 1.1 1 PMID:10548045 -3.4.23.39 lys-pro-ala-glu-phe-phe(no2)-arg-leu plasmodium falciparum 0.5 0.5 1 PMID:10548045 -3.4.23.39 lys-pro-asp-glu-phe-phe(no2)-arg-leu plasmodium falciparum 0.4 0.4 1 PMID:10548045 -3.4.23.39 lys-pro-ile-ala-phe-phe(no2)-arg-leu plasmodium falciparum 0.73 0.73 1 PMID:10548045 -3.4.23.39 lys-pro-ile-asp-phe-phe(no2)-arg-leu plasmodium falciparum 0.25 0.25 1 PMID:10548045 -3.4.23.39 lys-pro-ile-glu-phe-phe(no2)-ala-leu plasmodium falciparum 5.7 5.7 1 PMID:10548045 -3.4.23.39 lys-pro-ile-glu-phe-phe(no2)-arg-arg plasmodium falciparum 0.53 0.53 1 PMID:10548045 -3.4.23.39 lys-pro-ile-glu-phe-phe(no2)-arg-asp plasmodium falciparum 1.2 1.2 1 PMID:10548045 -3.4.23.39 lys-pro-ile-glu-phe-phe(no2)-arg-ile plasmodium falciparum 0.9 0.9 1 PMID:10548045 -3.4.23.39 lys-pro-ile-glu-phe-phe(no2)-arg-leu plasmodium falciparum 2.0 2.0 1 PMID:10548045 -3.4.23.39 lys-pro-ile-glu-phe-phe(no2)-arg-ser plasmodium falciparum 0.44 0.44 1 PMID:10548045 -3.4.23.39 lys-pro-ile-glu-phe-phe(no2)-arg-val plasmodium falciparum 0.7 0.7 1 PMID:10548045 -3.4.23.39 lys-pro-ile-glu-phe-phe(no2)-glu-leu plasmodium falciparum 6.3 6.3 1 PMID:10548045 -3.4.23.39 lys-pro-ile-glu-phe-phe(no2)-lys-leu plasmodium falciparum 1.6 1.6 1 PMID:10548045 -3.4.23.39 lys-pro-ile-glu-phe-phe(no2)-ser-leu plasmodium falciparum 1.7 1.7 1 PMID:10548045 -3.4.23.39 lys-pro-ile-glu-phe-phe(no2)-val-leu plasmodium falciparum 2.6 2.6 1 PMID:10548045 -3.4.23.39 lys-pro-ile-leu-phe-phe(no2)-arg-leu plasmodium falciparum 1.7 1.7 1 PMID:10548045 -3.4.23.39 lys-pro-ile-lys-phe-phe(no2)-arg-leu plasmodium falciparum 0.04 0.04 1 PMID:7925966;PMID:9561249 -3.4.23.39 lys-pro-ile-nle-phe-phe(no2)-arg-leu plasmodium falciparum 3.1 3.1 1 PMID:10548045 -3.4.23.39 lys-pro-ile-ser-phe-phe(no2)-arg-leu plasmodium falciparum 0.91 0.91 1 PMID:10548045 -3.4.23.39 lys-pro-ile-val-phe-phe(no2)-arg-leu plasmodium falciparum 3.6 2.6 2 PMID:7925966;PMID:9561249 -3.4.23.39 lys-pro-lys-glu-phe-phe(no2)-arg-leu plasmodium falciparum 0.1 0.1 1 PMID:10548045 -3.4.23.39 lys-pro-phe-glu-phe-phe(no2)-arg-leu plasmodium falciparum 2.4 2.4 1 PMID:10548045 -3.4.23.39 lys-pro-ser-glu-phe-phe(no2)-arg-leu plasmodium falciparum 0.32 0.32 1 PMID:10548045 -3.4.23.39 lys-ser-ile-glu-phe-phe(no2)-arg-leu plasmodium falciparum 1.3 1.3 1 PMID:10548045 -3.4.23.4 abz-a-a-f-f-a-a-n-(2,4-dinitrophenyl)-ethylenediamine bos taurus 1.6 0.16 3 PMID:16545070 -3.4.23.4 abz-a-a-f-f-a-a-p-nitroanilide bos taurus 1.4 1.4 1 PMID:16545070 -3.4.23.4 abz-a-a-f-f-a-n-(2,4-dinitrophenyl)-ethylenediamine bos taurus 0.8 0.11 3 PMID:16545070 -3.4.23.4 abz-a-a-f-f-n-(2,4-dinitrophenyl)-ethylenediamine bos taurus 0.27 0.27 1 PMID:16545070 -3.4.23.4 abz-a-a-f-f-p-nitroanilide bos taurus 0.48 0.48 1 PMID:16545070 -3.4.23.4 abz-a-f-f-a-a-n-(2,4-dinitrophenyl)-ethylenediamine bos taurus 0.14 0.1 2 PMID:16545070 -3.4.23.4 afpleferel bos taurus 2600.0 2600.0 1 PMID:19819898 -3.4.23.4 afpleffrel bos taurus 290.0 290.0 1 PMID:19819898 -3.4.23.4 afplefirel bos taurus 427.0 427.0 1 PMID:19819898 -3.4.23.4 afplefkrel bos taurus 29.0 29.0 1 PMID:19819898 -3.4.23.4 kappa-casein alces alces alces 98.69 98.69 1 PMID:37893665 -3.4.23.4 kappa-casein cervus canadensis sibiricus 2.68 2.68 1 PMID:33040722 -3.4.23.4 nt/nmn 142-151 callithrix jacchus 191.0 43.5 4 PMID:15568804 -3.4.23.4 pom c165-174 callithrix jacchus 219.0 141.0 2 PMID:15568804 -3.4.23.4 undecapeptide analogue to chymosin sensitive region of bovine kappa casein bos taurus 44.3 44.3 1 PMID:16488399 -3.4.23.4 undecapeptide analogue to chymosin sensitive region of bovine kappa-casein camelus dromedarius 11.7 11.7 1 PMID:16488399 -3.4.23.4 undecapeptide analogue to chymosin sensitive region of camel kappa casein bos taurus 4.3 4.3 1 PMID:16488399 -3.4.23.4 undecapeptide analogue to chymosin sensitive region of camel kappa-casein camelus dromedarius 5.1 5.1 1 PMID:16488399 -3.4.23.40 ((7-methoxycoumarin-4-yl)acetyl)-lys-lys-pro-ala-glu-phe-phe-ala-leu-lys-(2,4-dinitrophenyl) cynara cardunculus 36.5 24.0 3 PMID:28770303 -3.4.23.40 l-lys-l-pro-l-ala-l-glu-l-phe-l-phe(no2)-l-ala-l-leu cynara cardunculus 65.0 65.0 1 PMID:15677463 -3.4.23.40 l-pro-l-thr-l-glu-l-phe(p-no2)-l-phe-l-arg-l-leu cynara cardunculus var. scolymus 144.0 144.0 1 PMID:15649509 -3.4.23.40 leu-ser-phe(no2)-ahx-ala-leu-ome cynara cardunculus 86.2 49.95 2 PMID:8654427 -3.4.23.40 lys-pro-ala-glu-phe-phe-phe(no2)-ala-leu cynara cardunculus 89.4 72.515 2 PMID:8654427 -3.4.23.43 prepilin type iv pseudomonas aeruginosa 3.0 3.0 1 * -3.4.23.46 7-methoxycoumarin-4-yl-sevnldaefk-2,4-dinitrophenyl-rr homo sapiens 0.155 0.155 1 PMID:15003250 -3.4.23.46 eeisevnldaefrg homo sapiens 17.6 17.6 2 PMID:18177262 -3.4.23.46 re(edans)evnldaefk(dabcyl)r-nh2 homo sapiens 6.8e-05 6.8e-05 1 PMID:18979630 -3.4.23.46 sevnldaefr homo sapiens 10.7 10.7 2 PMID:18177262 -3.4.23.47 ac-tyr-arg-ala-arg-val-phe nph-val-arg-ala-ala-lys human immunodeficiency virus 2 0.00167 0.00167 1 PMID:8106448 -3.4.23.47 aetfyvdgaa human immunodeficiency virus 2 0.00283 0.0015485 2 PMID:2015912 -3.4.23.47 ctlnfpisp human immunodeficiency virus 2 0.0001 0.0001 1 PMID:2015912 -3.4.23.47 dkelypltsl human immunodeficiency virus 2 2.5e-05 2.5e-05 1 PMID:2015912 -3.4.23.47 ekggnypvqhv human immunodeficiency virus 2 0.00917 0.00486 2 PMID:2015912 -3.4.23.47 ipfaa-aqqrk human immunodeficiency virus 2 0.000217 0.000217 1 PMID:2015912 -3.4.23.47 ipfaaaqqrk human immunodeficiency virus 2 0.3 0.3 1 PMID:22238126 -3.4.23.47 irkilfldg human immunodeficiency virus 2 0.000333 0.000333 1 PMID:2015912 -3.4.23.47 karlm aealk human immunodeficiency virus 2 0.000333 0.000333 1 PMID:2015912 -3.4.23.47 karlmaealk human immunodeficiency virus 2 0.3 0.3 1 PMID:22238126 -3.4.23.47 karvl-aeams human immunodeficiency virus 2 0.00025 0.00025 1 PMID:2015912 -3.4.23.47 kprnfpvaqv human immunodeficiency virus 2 0.0117 0.005941500000000001 2 PMID:2015912 -3.4.23.47 l-threonyl-l-alanyl-l-threonyl-l-isoleucyl-l-methionyl-l-methionyl-l-glutaminyl-l-arginylglycyl-l-asparagine human immunodeficiency virus 2 0.000967 0.000967 1 PMID:2015912 -3.4.23.47 lys-ala-arg-ile-nle-nph-glu-ala-nle-nh2 human immunodeficiency virus 2 0.00722 0.00722 1 PMID:8106448 -3.4.23.47 lys-ala-arg-val-nle-(4-nitrophenylalanine)-glu-ala-nle human immunodeficiency virus 2 6.4 6.4 1 PMID:19798742 -3.4.23.47 lys-ala-arg-val-nle-p-nitrophenylalanine-glu-ala-nle-nh2 human immunodeficiency virus 2 5.3 5.3 1 PMID:18312292 -3.4.23.47 mslnlpvakv human immunodeficiency virus 2 0.000333 0.000333 1 PMID:2015912 -3.4.23.47 nh2-atlnfpspw-cooh human immunodeficiency virus 2 3.0 3.0 1 PMID:8505318 -3.4.23.47 rglaapqfsl human immunodeficiency virus 2 0.000717 0.000717 1 PMID:2015912 -3.4.23.47 rpqnflqsrp human immunodeficiency virus 2 5e-05 5e-05 1 PMID:2015912 -3.4.23.47 vlqnypivq human immunodeficiency virus 2 0.06 0.03001665 2 PMID:22238126;PMID:9725622 -3.4.23.47 vsqlypivq human immunodeficiency virus 2 0.4 0.20055 2 PMID:22238126;PMID:9725622 -3.4.23.47 vsqnypivq human immunodeficiency virus 2 0.00213 0.001925 2 PMID:2015912;PMID:9725622 -3.4.23.47 vsqnyplvq human immunodeficiency virus 2 0.00303 0.00303 1 PMID:9725622 -3.4.23.47 vsqvypivq human immunodeficiency virus 2 2.6 2.6 1 PMID:22238126 -3.4.23.47 vvqnypivq human immunodeficiency virus 2 0.16 0.16 1 PMID:22238126 -3.4.23.48 human glu-plasminogen yersinia pestis 0.0035 0.0035 1 PMID:19725923 -3.4.23.48 plasminogen yersinia pestis 0.0035 0.0035 1 * -3.4.23.49 2-aminobenzoyl-akka-3-[(2,4-dinitrophenyl)amino]-l-alanyl-gly escherichia coli 2380.0 2380.0 1 PMID:11327829 -3.4.23.49 2-aminobenzoyl-akra-3-[(2,4-dinitrophenyl)amino]-l-alanyl-gly escherichia coli 738.0 738.0 1 PMID:11327829 -3.4.23.49 2-aminobenzoyl-arka-3-[(2,4-dinitrophenyl)amino]-l-alanyl-gly escherichia coli 612.0 612.0 1 PMID:11327829 -3.4.23.49 2-aminobenzoyl-arra-3-[(2,4-dinitrophenyl)amino]-l-alanyl-gly escherichia coli 192.0 192.0 1 PMID:11327829 -3.4.23.49 2-aminobenzoyl-irra-3-[(2,4-dinitrophenyl)amino]-l-alanyl-gly escherichia coli 84.0 84.0 1 PMID:11327829 -3.4.23.49 2-aminobenzoyl-klksskq-n1-(2,4-dinitrophenyl)ethane-1,2-diamine phanerodontia chrysosporium 1.54 1.54 1 PMID:28193432 -3.4.23.49 2-aminobenzoyl-klrsskq-n1-(2,4-dinitrophenyl)ethane-1,2-diamine phanerodontia chrysosporium 1.15 1.15 1 PMID:28193432 -3.4.23.49 2-aminobenzoyl-kmrsskq-n1-(2,4-dinitrophenyl)ethane-1,2-diamine phanerodontia chrysosporium 0.64 0.64 1 PMID:28193432 -3.4.23.49 2-aminobenzoyl-knrsskq-n1-(2,4-dinitrophenyl)ethane-1,2-diamine phanerodontia chrysosporium 0.8 0.8 1 PMID:28193432 -3.4.23.49 2-aminobenzoyl-kqrsskq-n1-(2,4-dinitrophenyl)ethane-1,2-diamine phanerodontia chrysosporium 0.824 0.824 1 PMID:28193432 -3.4.23.49 2-aminobenzoyl-rra-3-[(2,4-dinitrophenyl)amino]-l-alanyl-gly escherichia coli 78.0 78.0 1 PMID:11327829 -3.4.23.49 ac-gllgdfarrakekigc escherichia coli 12.9 12.9 1 PMID:28940795 -3.4.23.49 ac-gllgdffrkskekigc escherichia coli 0.3 0.3 1 PMID:28940795 -3.4.23.49 ac-gllgdffrrvkekigc escherichia coli 57.6 57.6 1 PMID:28940795 -3.4.23.49 aminobenzoyl-ala-lys-lys-ala-3-(dinitrophenyl)diaminopropionic acid-gly escherichia coli 2400.0 2400.0 1 PMID:11327829 -3.4.23.49 artkqtar(me1)kstggk escherichia coli 1.7 1.7 1 PMID:31775502 -3.4.23.49 artkqtar(me2as)kstggk escherichia coli 0.1 0.1 1 PMID:31775502 -3.4.23.49 artkqtar(me2s)kstggk escherichia coli 0.3 0.3 1 PMID:31775502 -3.4.23.49 artkqtark(ac)stggk escherichia coli 0.8 0.8 1 PMID:31775502 -3.4.23.49 artkqtark(me1)stggk escherichia coli 2.4 2.4 1 PMID:31775502 -3.4.23.49 artkqtark(me2)stggk escherichia coli 2.1 2.1 1 PMID:31775502 -3.4.23.49 artkqtark(me3)stggk escherichia coli 2.7 2.7 1 PMID:31775502 -3.4.23.49 artkqtarkstggk escherichia coli 2.9 2.9 1 PMID:31775502 -3.4.23.49 elelykrhhg escherichia coli 660.0 660.0 1 PMID:12241547 -3.4.23.49 elrlykrhhg escherichia coli 3720.0 3720.0 2 PMID:11866094;PMID:12241547 -3.4.23.49 elrlyrnhhg escherichia coli 23.4 23.4 1 PMID:11866094 -3.4.23.49 elrlyrrhhg escherichia coli 1560.0 1560.0 1 PMID:11866094 -3.4.23.49 iaa-arg-arg-p-nitroanilide escherichia coli 24.0 21.0 2 PMID:10651827 -3.4.23.49 o-aminobenzoyl-ala-arg-arg-ala-3-nitrotyrosine-nh2 escherichia coli 2460.0 2280.0 3 PMID:10651827 -3.4.23.49 rlelykrhhg escherichia coli 378.0 378.0 1 PMID:12241547 -3.4.23.49 rlrlykrhhg escherichia coli 372.0 372.0 1 PMID:12241547 -3.4.23.49 wcarvgkgrgr-nh2 escherichia coli 0.031 0.031 1 PMID:15867160 -3.4.23.49 weeggrrigrggk escherichia coli 8.8 6.1000000000000005 2 PMID:17085556 -3.4.23.49 weeggrrigrggk-nh2 escherichia coli 8.8 8.8 1 PMID:15867160 -3.4.23.49 wlaakkgag escherichia coli 13.0 7.1 2 PMID:17085556 -3.4.23.49 wlaarrgag escherichia coli 13.0 10.5 2 PMID:17085556 -3.4.23.49 wlaarrgrg escherichia coli 900.0 515.0 2 PMID:17085556 -3.4.23.49 wlaasrgag escherichia coli 0.17 0.1 2 PMID:17085556 -3.4.23.49 wlarrrgag escherichia coli 2.2 1.7000000000000002 2 PMID:17085556 -3.4.23.49 wlatrrgag escherichia coli 9.0 7.0 2 PMID:17085556 -3.4.23.49 wlrarrgag escherichia coli 37.0 21.0 2 PMID:17085556 -3.4.23.49 wlsarrgag escherichia coli 168.0 117.5 2 PMID:17085556 -3.4.23.49 wlserrgag escherichia coli 1.5 1.05 2 PMID:17085556 -3.4.23.5 (7-methoxycoumarin-4-yl)acetyl-gly-lys-pro-ile-ile-phe-phe-arg-leu-lys(dnp)-d-arg-nh2 rattus norvegicus 59.6 59.6 1 PMID:15843176 -3.4.23.5 (7-methoxycoumarin-4-yl)acetyl-gly-ser-pro-ala-phe-leu-ala-lys(dnp)-d-arg-nh2 rattus norvegicus 2.5 2.35 2 PMID:15843176 -3.4.23.5 (7-methoxycoumarin-4-yl)acetyl-gly-ser-ser-ala-phe-leu-ala-phe-lys(dnp)-d-arg-nh2 rattus norvegicus 0.75 0.75 1 PMID:15843176 -3.4.23.5 2-aminobenzoyl-aakffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.6 2.6 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aekffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 6.18 6.18 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aiaffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 16.3 16.3 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aieffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 7.48 4.015000000000001 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aiiffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.47 0.47 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffarq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.9 3.9 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikfferq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.94 2.61 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffirq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.65 0.65 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffkrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.65 0.65 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikfflrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.94 2.285 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffnrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 6.08 3.5300000000000002 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikfforq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.3 1.3 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffrrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.95 1.95 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffsa-(n-(2,4-dinitrophenyl)ethylenediamine) homo sapiens 4.16 3.645 2 PMID:11131147 -3.4.23.5 2-aminobenzoyl-aikffsaq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 6.34 6.34 3 PMID:11131147;PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffsaqtnrhilrfnr-(n-(2,4-dinitrophenyl)ethylenediamine) homo sapiens 2.94 2.44 3 PMID:11131147 -3.4.23.5 2-aminobenzoyl-aikffsaqtnrhilrfnrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.94 2.69 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffsaqtnrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.99 0.99 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffseq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.58 3.355 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffsiq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.94 2.285 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffskq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.3 1.3 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffslq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.6 2.6 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffsnq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.25 3.25 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffsoq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 4.88 4.09 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffspq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.3 1.3 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 4.88 4.09 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffssq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 6.08 3.5300000000000002 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffstq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.6 2.6 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffsvq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.94 2.61 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikfftrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.94 2.285 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikffvrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.94 2.285 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikfmsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.3 1.3 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aiklfsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 7.15 3.85 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikllsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 6.08 3.5300000000000002 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aiklmsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.94 2.61 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikmflrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.3 1.3 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikmfsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.52 0.52 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikmmsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.3 1.3 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aikyysrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.6 2.6 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-ailffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 7.8 7.8 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aimffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.94 2.705 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-ainffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 8.45 8.45 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aipffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.081 0.081 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aiqffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.41 0.41 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aisffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 8.78 5.375 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aitffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 5.53 5.53 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aivffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 6.08 3.46 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-akkffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 1.3 1.3 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-alkffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.97 0.97 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-ankffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 5.85 5.85 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-apkffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 6.0 4.465 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-aqkffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 2.94 2.61 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-askffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 0.65 0.65 1 PMID:11341921 -3.4.23.5 2-aminobenzoyl-atkffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 3.58 3.355 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-avkffsrq-n-(2,4-dinitrophenyl)ethylenediamine homo sapiens 8.78 5.375 2 PMID:11341921 -3.4.23.5 2-aminobenzoyl-kitllsalvetrivrfnrq-(n-(2,4-dinitrophenyl)ethylenediamine) homo sapiens 0.17 0.17 1 PMID:11131147 -3.4.23.5 2-aminobenzoyl-kitllsalvetrq-(n-(2,4-dinitrophenyl)ethylenediamine) homo sapiens 2.8 2.8 1 PMID:11131147 -3.4.23.5 2-aminobenzoyl-kitllsaq-(n-(2,4-dinitrophenyl)ethylenediamine) homo sapiens 3.6 2.95 2 PMID:11131147 -3.4.23.5 eeisevnldaefrg homo sapiens 31.4 31.4 1 PMID:18177262 -3.4.23.5 eeisevnldaefrg sus scrofa 56.1 28.8 2 PMID:18177262 -3.4.23.5 fibrinogen homo sapiens 0.0014 0.0014 1 PMID:8204591 -3.4.23.5 glu-glu-his-phe-phe-ala-ala homo sapiens 0.4 0.4 1 * -3.4.23.5 glu-glu-his-phe-phe-ala-leu-methyl ester homo sapiens 2.1 2.1 1 * -3.4.23.5 lys-pro-ile-glu-phe-(4-nitro)phe-arg-leu rattus norvegicus 65.0 50.0 3 PMID:3202970 -3.4.23.5 phe-ala-ala-(4-nitro)phe-phe-val-leu-4-hydroxymethylpyridine ester sus scrofa 2.9 2.9 1 PMID:6869796 -3.4.23.5 phe-gly-gly-(4-nitro)phe-phe-val-leu-methyl ester sus scrofa 0.6 0.6 1 PMID:6869796 -3.4.23.5 pro-pro-thr-ile-phe-(4-nitro)phe-arg-leu rattus norvegicus 95.0 30.0 3 PMID:3202970 -3.4.23.5 sevnldaefr homo sapiens 8.8 8.8 1 PMID:18177262 -3.4.23.5 sevnldaefr sus scrofa 29.0 29.0 1 PMID:18177262 -3.4.23.50 2-aminobenzoyl-ala-thr-his-gln-val-tyr-phe(no2)-val-arg-lys-ala homo sapiens 1.37 0.75 2 PMID:11278433 -3.4.23.50 lys-ala-arg-val-tyr-phe(no2)-glu-ala-nle-nh2 homo sapiens 2.1 1.4500000000000002 2 PMID:9860826 -3.4.24.11 adrenocorticotropic hormone lactococcus lactis 1.7 1.7 1 PMID:8806762 -3.4.24.11 alpha-endorphin homo sapiens 8.9 8.9 1 PMID:25089527 -3.4.24.11 alpha-neoendorphin lactococcus lactis 44.6 44.6 1 PMID:8806762 -3.4.24.11 amyloid beta peptide1-40 homo sapiens 0.83 0.83 1 PMID:25089527 -3.4.24.11 angiotensin homo sapiens 8.2 8.2 1 PMID:25089527 -3.4.24.11 angiotensin i homo sapiens 0.0551 0.0551 1 PMID:15283675 -3.4.24.11 angiotensin ii homo sapiens 40.0 40.0 1 PMID:15283675 -3.4.24.11 angiotensin(1-9) homo sapiens 41.8 41.8 1 PMID:15283675 -3.4.24.11 arg-vasopressin homo sapiens 2.8 2.8 1 PMID:25089527 -3.4.24.11 benzoyl-gly-gly-arg-leu-2-naphthylamide bos taurus 0.05 0.05 1 PMID:7028098 -3.4.24.11 benzyloxycarbonyl-ala-gly-leu-ala rattus norvegicus 46.4 46.4 1 PMID:3522576 -3.4.24.11 beta-endorphin lactococcus lactis 26.0 26.0 1 PMID:8806762 -3.4.24.11 bradykinin homo sapiens 16.0 16.0 1 PMID:25089527 -3.4.24.11 bradykinin lactococcus lactis 4.3 4.3 1 PMID:8806762 -3.4.24.11 bradykinin rattus norvegicus 106.0 106.0 1 PMID:2461706 -3.4.24.11 d-ala2-leu5-enkephalin canis lupus familiaris 20.7 19.85 2 PMID:8489505 -3.4.24.11 d-ala2-leu5-enkephalin oryctolagus cuniculus 1020.0 1020.0 1 PMID:9247159 -3.4.24.11 dansyl-gly-trp-gly rattus norvegicus 15.0 15.0 1 PMID:3548727 -3.4.24.11 dansyl-gly-tyr-gly rattus norvegicus 19.1 19.1 1 PMID:3548727 -3.4.24.11 dansyl-gly-tyr-gly-nh2 rattus norvegicus 4.13 4.13 1 PMID:3548727 -3.4.24.11 dynorphin a-10 lactococcus lactis 23.8 23.8 1 PMID:8806762 -3.4.24.11 dynorphin a-13 lactococcus lactis 18.6 18.6 1 PMID:8806762 -3.4.24.11 dynorphin a-17 lactococcus lactis 25.4 25.4 1 PMID:8806762 -3.4.24.11 dynorphin a-6 lactococcus lactis 14.0 14.0 1 PMID:8806762 -3.4.24.11 dynorphin a-8 lactococcus lactis 19.6 19.6 1 PMID:8806762 -3.4.24.11 dynorphin a-9 lactococcus lactis 32.2 32.2 1 PMID:8806762 -3.4.24.11 endothelin-1 homo sapiens 0.68 0.68 1 PMID:25089527 -3.4.24.11 gamma-endorphin homo sapiens 4.8 4.8 1 PMID:25089527 -3.4.24.11 gastri-releasing peptide homo sapiens 26.0 26.0 1 PMID:25089527 -3.4.24.11 gastrin g-17 homo sapiens 1.07 0.9185000000000001 2 PMID:2736261 -3.4.24.11 glp-1 homo sapiens 3.3 3.3 1 PMID:25089527 -3.4.24.11 glucagon homo sapiens 4.5 4.5 1 PMID:25089527 -3.4.24.11 glutaryl-ala-ala-phe-2-naphthylamide bos taurus 9.87 9.87 1 PMID:7028098 -3.4.24.11 glutaryl-ala-ala-phe-4-methoxy-2-naphthylamide bos taurus 5.28 5.28 1 PMID:7028098 -3.4.24.11 glutaryl-ala-ala-phe-4-methoxy-2-naphthylamine rattus norvegicus 58.2 58.2 1 PMID:3522576 -3.4.24.11 glutaryl-gly-gly-phe-2-naphthylamide sus scrofa 43.7 43.7 1 PMID:6349615 -3.4.24.11 gly-trp-gly rattus norvegicus 0.883 0.883 1 PMID:3548727 -3.4.24.11 hippuryl-arg-arg-ala-2-naphthylamide rattus norvegicus 6.83 6.83 1 PMID:7049171 -3.4.24.11 hippuryl-arg-arg-leu-2-naphthylamide rattus norvegicus 72.0 72.0 1 PMID:7049171 -3.4.24.11 leu-enkephalin lactococcus lactis 15.0 15.0 1 PMID:8806762 -3.4.24.11 leu-enkephalinamide lactococcus lactis 8.2 8.2 1 PMID:8806762 -3.4.24.11 luteinizing hormone-releasing hormone rattus norvegicus 14.0 14.0 1 PMID:2461706 -3.4.24.11 met-enkephalin lactococcus lactis 7.8 7.8 1 PMID:8806762 -3.4.24.11 met-enkephalin amide lactococcus lactis 0.5 0.5 1 PMID:8806762 -3.4.24.11 n-acetyl-gly-trp-gly rattus norvegicus 3.63 3.63 1 PMID:3548727 -3.4.24.11 n-benzyoxycarbonyl-gly-gly-leu-2-naphthylamide bos taurus 0.105 0.105 1 PMID:7028098 -3.4.24.11 nalpha-benzoyl-gly-arg-arg-ala-2-naphthylamide bos taurus 0.147 0.147 1 PMID:7028098 -3.4.24.11 nalpha-benzoyl-gly-arg-arg-leu-2-naphthylamide bos taurus 4.0 4.0 1 PMID:7028098 -3.4.24.11 nalpha-benzoyl-gly-arg-arg-phe-2-naphthylamide bos taurus 2.0 2.0 1 PMID:7028098 -3.4.24.11 nalpha-benzoyl-gly-arg-leu-2-naphthylamide bos taurus 0.0483 0.0483 1 PMID:7028098 -3.4.24.11 nalpha-benzoyl-gly-lys-arg-arg-leu-2-naphthylamide bos taurus 1.82 1.82 1 PMID:7028098 -3.4.24.11 nalpha-benzoyl-gly-lys-lys-arg-arg-leu-2-naphthylamide bos taurus 0.383 0.383 1 PMID:7028098 -3.4.24.11 neurokinin a homo sapiens 17.0 17.0 1 PMID:25089527 -3.4.24.11 neurokinin b homo sapiens 20.0 20.0 1 PMID:25089527 -3.4.24.11 neurotensin homo sapiens 13.0 13.0 1 PMID:25089527 -3.4.24.11 nociceptin homo sapiens 11.0 11.0 1 PMID:25089527 -3.4.24.11 somatostatin 14 homo sapiens 32.0 32.0 1 PMID:25089527 -3.4.24.11 somatostatin 28 homo sapiens 9.1 9.1 1 PMID:25089527 -3.4.24.11 substance p homo sapiens 18.0 18.0 1 PMID:25089527 -3.4.24.11 substance p lactococcus lactis 28.0 28.0 1 PMID:8806762 -3.4.24.11 substance p rattus norvegicus 84.3 84.3 1 PMID:2461706 -3.4.24.11 substance p sus scrofa 84.4 84.4 1 PMID:6149747 -3.4.24.11 succinyl-arg-arg-leu-2-naphthylamide bos taurus 6.32 6.32 1 PMID:7028098 -3.4.24.11 sulfated cholecystokinin octapeptide homo sapiens 31.1 31.1 1 PMID:2736261 -3.4.24.11 tyr-d-ala-gly-phe-met rattus norvegicus 17.4 17.4 1 PMID:7049171 -3.4.24.11 tyr-d-ala-gly-phe-met-nh2 rattus norvegicus 42.0 42.0 1 PMID:7049171 -3.4.24.11 tyr-gly-gly-phe-met rattus norvegicus 21.1 21.1 1 PMID:7049171 -3.4.24.11 unsulfated cholecystokinin octapeptide homo sapiens 24.6 24.6 1 PMID:2736261 -3.4.24.11 vasoactive intestinal peptide lactococcus lactis 1.8 1.8 1 PMID:8806762 -3.4.24.12 dimethylated casein paracentrotus lividus 180.0 180.0 1 PMID:2925668 -3.4.24.12 dimethylated casein strongylocentrotus purpuratus 0.72 0.379 2 PMID:1012003;PMID:20058 -3.4.24.14 procollagen i bos taurus 0.08 0.08 1 PMID:8157670 -3.4.24.14 procollagen i gallus gallus 0.0967 0.0967 1 PMID:2500439 -3.4.24.15 (7-methoxycoumarin-4-yl)-acetyl-pro-leu-gly-pro-d-lys-(2,4-dinitrophenyl) rattus norvegicus 0.4 0.4 1 PMID:35806299 -3.4.24.15 (7-methoxycoumarin-4-yl)acetyl-glu-his-trp-ser-tyr-gly-leu-arg-pro-oh rattus norvegicus 11.2 11.2 1 PMID:18959747 -3.4.24.15 (7-methoxycoumarin-4-yl)acetyl-leu-glu-asn-lys-pro-arg-arg-pro-lys(dnp)-oh rattus norvegicus 0.33 0.33 1 PMID:18959747 -3.4.24.15 (o-aminobenzoyl)-afspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 9.8 6.2 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-akprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 0.75 0.75 1 PMID:11355859 -3.4.24.15 (o-aminobenzoyl)-dfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 4.7 2.85 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-efspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 6.08 1.4 3 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-ffspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 1.6 1.6 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gaspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 2.5 2.5 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gdspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 2.2 2.2 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gespfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 5.8 5.8 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfapfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 5.7 5.7 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfdpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.4 3.4 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfepfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 4.0 4.0 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gffpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 5.3 5.3 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfhpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 6.08 3.485 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfipfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 4.9 4.9 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gflpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.0 3.0 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfnpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 2.5 2.5 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfppfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 1.6 1.6 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfqpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 1.8 1.8 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfrpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 7.7 7.7 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfsafrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 10.2 10.2 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfsdfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 24.7 24.7 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfsefrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 0.7 0.7 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfsffrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 6.7 6.7 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfshfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 7.0 7.0 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfslfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.4 3.4 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfsnfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 8.9 8.9 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfsparq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 18.5 18.5 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspdrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 8.9 8.55 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfsperq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 1.8 1.65 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfaq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 2.3 2.3 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfdq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 4.0 4.0 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfeq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 11.8 6.7 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspffq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 1.1 1.1 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfhq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.0 2.4 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfiq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 11.1 11.1 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspflq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.1 3.1 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfnq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 7.9 6.050000000000001 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfpq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 7.0 7.0 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfqq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 6.08 2.3 3 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfra-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 17.5 17.5 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfre-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.1 3.1 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfrf-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 7.1 7.1 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfri-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.0 3.0 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfrl-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 4.8 4.8 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfrn-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 12.3 12.3 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfrp-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 2.6 2.6 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 6.3 6.3 3 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfrr-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 6.08 3.425 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfrs-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 4.3 4.3 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspfsq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 1.4 1.2999999999999998 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfsphrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 5.3 5.3 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspirq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 5.9 4.85 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfsplrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 6.08 4.2 3 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspnrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 10.1 10.1 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspqrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 12.3 12.3 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfsprrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 2.7 2.7 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfspsrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 21.5 21.5 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfsqfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 1.5 1.5 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfsrfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 6.3 6.3 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfssfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 8.8 8.8 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gfsxfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 6.3 6.3 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-ggflrraq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 3.2 3.2 1 PMID:12199711 -3.4.24.15 (o-aminobenzoyl)-ggflrrdq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.0 1.0 1 PMID:12199711 -3.4.24.15 (o-aminobenzoyl)-ggflrreq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.1 1.1 1 PMID:12199711 -3.4.24.15 (o-aminobenzoyl)-ggflrrfq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.3 0.25 2 PMID:12199711 -3.4.24.15 (o-aminobenzoyl)-ggflrrhq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.6 1.1 2 PMID:12199711 -3.4.24.15 (o-aminobenzoyl)-ggflrriq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.7 0.39999999999999997 2 PMID:12199711 -3.4.24.15 (o-aminobenzoyl)-ggflrrlq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.5 0.35 2 PMID:12199711 -3.4.24.15 (o-aminobenzoyl)-ggflrrnq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.6 0.44999999999999996 2 PMID:12199711 -3.4.24.15 (o-aminobenzoyl)-ggflrrpq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.8 1.8 1 PMID:12199711 -3.4.24.15 (o-aminobenzoyl)-ggflrrrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 3.3 3.3 1 PMID:12199711 -3.4.24.15 (o-aminobenzoyl)-ggflrrv-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 2.0 2.0 1 PMID:12199711 -3.4.24.15 (o-aminobenzoyl)-ggflrrvq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.4 1.4 1 PMID:12199711 -3.4.24.15 (o-aminobenzoyl)-ggflrryq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.3 0.25 2 PMID:12199711 -3.4.24.15 (o-aminobenzoyl)-ghspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 14.5 14.5 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gispfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 8.4 8.4 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-glspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 11.5 11.5 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gnspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 5.2 5.2 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gpspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 11.5 11.5 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gqspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 2.9 2.9 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-grspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 13.3 13.3 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-gsspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.2 3.2 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-hfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 6.0 6.0 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-ifspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 6.08 1.5 3 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-lfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.8 3.0 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-naprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.6 3.6 1 PMID:11355859 -3.4.24.15 (o-aminobenzoyl)-nfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.0 1.875 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-nkarrpq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 8.0 8.0 1 PMID:11355859 -3.4.24.15 (o-aminobenzoyl)-nkparpq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 4.2 4.2 1 PMID:11355859 -3.4.24.15 (o-aminobenzoyl)-nkprapq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 8.7 8.7 1 PMID:11355859 -3.4.24.15 (o-aminobenzoyl)-nkprrapq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 5.7 5.7 1 PMID:11355859 -3.4.24.15 (o-aminobenzoyl)-qfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 4.7 2.9000000000000004 2 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-rfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 4.3 4.3 1 PMID:11284698 -3.4.24.15 (o-aminobenzoyl)-sfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 6.08 4.1 3 PMID:11284698 -3.4.24.15 (ortho-aminobenzoyl)-enkprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.2 3.2 1 PMID:11355859 -3.4.24.15 (ortho-aminobenzoyl)-ggflprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.7 3.7 1 PMID:11355859 -3.4.24.15 (ortho-aminobenzoyl)-kprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 3.7 3.7 1 PMID:11355859 -3.4.24.15 (ortho-aminobenzoyl)-lyenkprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 0.3 0.3 1 PMID:11355859 -3.4.24.15 (ortho-aminobenzoyl)-nkprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 0.7 0.7 1 PMID:11355859 -3.4.24.15 2-aminobenzoyl-gfspfrq-(n-2,4-dinitrophenyl)ethylenediamine rattus norvegicus 6.3 6.3 1 PMID:17313369 -3.4.24.15 7-methoxycoumarin-4-acetyl-(l-ala-l-lys(2,4-dinitrophenyl))-bradykinin rattus norvegicus 1.07 0.815 4 PMID:15647004 -3.4.24.15 7-methoxycoumarin-4-acetyl-[ala7, lys(dinitrophenol)9]-bradykinin rattus norvegicus 0.3 0.3 1 PMID:18959747 -3.4.24.15 7-methoxycoumarin-4-acetyl-pro-leu-gly-pro-lys-dinitrophenol rattus norvegicus 0.44 0.44 1 PMID:18959747 -3.4.24.15 7-methoxycoumarin-4-acetyl-pro-leu-gly-pro-lys-dinitrophenyl rattus norvegicus 9.9 9.9 1 PMID:12804780 -3.4.24.15 abz-gfsafrq-eddnp homo sapiens 11.1 11.1 1 PMID:20226173 -3.4.24.15 abz-gfsafrqeddnp rattus norvegicus 10.2 10.2 1 PMID:17313369 -3.4.24.15 abz-gfsdfrq-eddnp homo sapiens 0.3 0.3 1 PMID:20226173 -3.4.24.15 abz-gfsefrq-eddnp homo sapiens 1.6 1.6 1 PMID:20226173 -3.4.24.15 abz-gfsefrqeddnp rattus norvegicus 1.5 1.5 1 PMID:17313369 -3.4.24.15 abz-gfsffrq-eddnp homo sapiens 5.9 5.9 1 PMID:20226173 -3.4.24.15 abz-gfsffrqeddnp rattus norvegicus 6.7 6.7 1 PMID:17313369 -3.4.24.15 abz-gfshfrq-eddnp homo sapiens 13.3 13.3 1 PMID:20226173 -3.4.24.15 abz-gfshfrqeddnp rattus norvegicus 24.7 24.7 1 PMID:17313369 -3.4.24.15 abz-gfsifrq-eddnp homo sapiens 0.19 0.19 1 PMID:20226173 -3.4.24.15 abz-gfsifrqeddnp rattus norvegicus 0.001 0.001 1 PMID:17313369 -3.4.24.15 abz-gfslfrqeddnp rattus norvegicus 3.4 3.4 1 PMID:17313369 -3.4.24.15 abz-gfsparq-eddnp homo sapiens 1.7 1.7 1 PMID:20226173 -3.4.24.15 abz-gfspdrq-eddnp homo sapiens 0.03 0.03 1 PMID:20226173 -3.4.24.15 abz-gfsperq-eddnp homo sapiens 0.01 0.01 1 PMID:20226173 -3.4.24.15 abz-gfspfrq-eddnp homo sapiens 2.9 2.9 1 PMID:20226173 -3.4.24.15 abz-gfsphrq-eddnp homo sapiens 0.3 0.3 1 PMID:20226173 -3.4.24.15 abz-gfspirq-eddnp homo sapiens 0.04 0.04 1 PMID:20226173 -3.4.24.15 abz-gfsplrq-eddnp homo sapiens 0.02 0.02 1 PMID:20226173 -3.4.24.15 abz-gfspqrq-eddnp homo sapiens 0.7 0.7 1 PMID:20226173 -3.4.24.15 abz-gfsprrq-eddnp homo sapiens 4.5 4.5 1 PMID:20226173 -3.4.24.15 abz-gfspsrq-eddnp homo sapiens 0.4 0.4 1 PMID:20226173 -3.4.24.15 abz-gfsqfrq-eddnp homo sapiens 7.0 7.0 1 PMID:20226173 -3.4.24.15 abz-gfsqfrqeddnp rattus norvegicus 6.3 6.3 1 PMID:17313369 -3.4.24.15 abz-gfsrfrq-eddnp homo sapiens 9.1 9.1 1 PMID:20226173 -3.4.24.15 abz-gfsrfrqeddnp rattus norvegicus 7.0 7.0 1 PMID:17313369 -3.4.24.15 abz-gfssfrq-eddnp homo sapiens 9.2 9.2 1 PMID:20226173 -3.4.24.15 abz-gfssfrqeddnp rattus norvegicus 8.8 8.8 1 PMID:17313369 -3.4.24.15 abz-gfswfrq-eddnp homo sapiens 6.0 6.0 1 PMID:20226173 -3.4.24.15 abz-gfswfrqeddnp rattus norvegicus 2.7 2.7 1 PMID:17313369 -3.4.24.15 abz-gfsyfrqeddnp rattus norvegicus 6.2 6.2 1 PMID:17313369 -3.4.24.15 arg-pro-pro-gly-phe-ser-pro-phe-arg rattus norvegicus 33.8 33.8 1 PMID:2803255 -3.4.24.15 benzoyl-gly-ala-ala-gly rattus norvegicus 5.3 5.3 1 PMID:2803255 -3.4.24.15 benzoyl-gly-ala-ala-gly-p-aminobenzoate rattus norvegicus 1.15 1.15 1 PMID:6349998 -3.4.24.15 benzoyl-gly-ala-ala-leu-p-aminobenzoate rattus norvegicus 17.0 10.05 2 PMID:2803255;PMID:6349998 -3.4.24.15 benzoyl-gly-ala-ala-phe-p-aminobenzoate rattus norvegicus 179.0 48.3 3 PMID:2803255;PMID:6349998 -3.4.24.15 benzoyl-gly-arg-ala-ala-phe-4-aminobenzoate rattus norvegicus 5.25 5.25 1 PMID:6349998 -3.4.24.15 benzoyl-gly-asp-ala-ala-phe-4-aminobenzoate rattus norvegicus 2.2 2.2 1 PMID:6349998 -3.4.24.15 benzoyl-gly-gly-ala-phe-p-aminobenzoate rattus norvegicus 4.54 2.995 2 PMID:2803255;PMID:6349998 -3.4.24.15 benzoyl-gly-lys-arg-ala-ala-phe-p-aminobenzoate rattus norvegicus 10.1 10.1 1 PMID:6349998 -3.4.24.15 benzoyl-gly-phe-ala-ala-phe-p-aminobenzoate rattus norvegicus 8.6 5.675 2 PMID:6349998 -3.4.24.15 benzoyl-gly-phe-ala-phe-p-aminobenzoate rattus norvegicus 19.2 19.2 1 PMID:2803255 -3.4.24.15 benzoyl-gly-phe-phe-ala-ala-phe-p-aminobenzoate rattus norvegicus 6.2 6.2 1 PMID:6349998 -3.4.24.15 neurotensin homo sapiens 2.3 2.3 1 PMID:17251185 -3.4.24.15 pglu-his-trp-ser-tyr-gly-leu-arg-pro-gly-nh2 rattus norvegicus 12.0 12.0 1 PMID:2803255 -3.4.24.15 pglu-leu-tyr-glu-asn-lys-pro-arg-arg-pro-tyr-ile-leu rattus norvegicus 7.9 7.9 1 PMID:2803255 -3.4.24.15 tert-butoxycarbonyl-phe-ala-ala-phe-p-aminobenzoate rattus norvegicus 94.1 57.8 2 PMID:2803255;PMID:6349998 -3.4.24.15 tyr-gly-gly-phe-leu-arg-arg-ile rattus norvegicus 86.4 86.4 1 PMID:2803255 -3.4.24.15 tyr-gly-gly-phe-leu-arg-lys-tyr-pro rattus norvegicus 37.9 37.9 1 PMID:2803255 -3.4.24.16 (7-methoxy-coumarin-4-yl)acetyl-rpkpve-nva-wrk(2,4-dinitrophenyl)-nh2 rattus norvegicus 0.76 0.76 1 PMID:18499680 -3.4.24.16 (7-methoxy-coumarin-4-yl)acetyl-rpkpya-nva-wmk(2,4-dinitrophenyl)-nh2 rattus norvegicus 2.1 2.1 1 PMID:18499680 -3.4.24.16 (7-methoxycoumarin-4-yl)acetyl-gly-gly-phe-ile-arg-arg-ala-lys-dinitrophenyl rattus norvegicus 11.9 11.9 1 PMID:7836437 -3.4.24.16 (7-methoxycoumarin-4-yl)acetyl-gly-gly-phe-leu-arg-arg-ala-lys-dinitrophenyl rattus norvegicus 2.1 2.1 1 PMID:7836437 -3.4.24.16 (o-aminobenzoyl)-afspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.27 0.185 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-akprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.00497 0.00497 1 PMID:11355859 -3.4.24.16 (o-aminobenzoyl)-dfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.12 0.06999999999999999 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-efspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.08 0.045 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-enkprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.35 1.35 1 PMID:11355859 -3.4.24.16 (o-aminobenzoyl)-ffspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.23 0.13 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gaspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.3 1.3 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gdspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.34 0.34 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gespfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 3.46 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfapfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.8 0.8 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfdpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.2 0.2 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfepfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.07 0.07 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gffpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 3.68 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfhpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 3.3 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfipfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.27 0.27 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gflpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.24 0.24 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfnpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 3.36 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfppfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 3.35 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfqpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.39 0.39 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfrpfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 3.525 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsafrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 2.6 2.6 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsdfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 2.5 2.5 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsefrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.19 0.19 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsffrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 3.4 3.4 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfshfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 4.8 4.8 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsifrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.22 0.22 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfslfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 3.5 3.5 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsnfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 8.8 8.8 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsparq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.4 0.4 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspdrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.24 0.135 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsperq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.65 0.395 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfaq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.4 1.35 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfdq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.8 1.8 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfeq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.6 0.9450000000000001 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspffq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.4 0.8999999999999999 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfhq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 1.4 3 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfiq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 3.345 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspflq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 5.9 5.9 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfnq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 1.1 3 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfpq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.4 1.4 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfqq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 3.4050000000000002 4 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfra-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 3.0 3.0 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfre-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.1 1.1 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfrf-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.8 1.8 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfri-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.9 1.9 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfrl-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 7.4 7.4 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfrn-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.9 1.9 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfrp-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 3.455 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.31 0.31 3 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfrr-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.45 0.45 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfrs-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 2.1 2.1 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspfsq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.3 1.2000000000000002 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsphrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.19 0.19 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspirq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 0.65 3 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsplrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.3 0.925 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspnrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 3.35 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspprq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.15 0.15 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspqrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 2.6 2.6 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsprrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.42 0.42 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfspsrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.5 1.5 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsqfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 3.375 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsrfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.31 0.31 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfssfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 7.5 7.5 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gfsxfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 3.6 3.6 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-ggflprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 2.94 2.355 2 PMID:11355859 -3.4.24.16 (o-aminobenzoyl)-ggflrraq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 3.2 3.2 1 PMID:12199711 -3.4.24.16 (o-aminobenzoyl)-ggflrrdq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.0 1.0 1 PMID:12199711 -3.4.24.16 (o-aminobenzoyl)-ggflrreq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.1 1.1 1 PMID:12199711 -3.4.24.16 (o-aminobenzoyl)-ggflrrfq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.3 0.25 2 PMID:12199711 -3.4.24.16 (o-aminobenzoyl)-ggflrrhq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.6 1.1 2 PMID:12199711 -3.4.24.16 (o-aminobenzoyl)-ggflrriq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.7 0.39999999999999997 2 PMID:12199711 -3.4.24.16 (o-aminobenzoyl)-ggflrrlq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.5 0.35 2 PMID:12199711 -3.4.24.16 (o-aminobenzoyl)-ggflrrnq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.6 0.44999999999999996 2 PMID:12199711 -3.4.24.16 (o-aminobenzoyl)-ggflrrpq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.8 1.8 1 PMID:12199711 -3.4.24.16 (o-aminobenzoyl)-ggflrrrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 3.3 3.3 1 PMID:12199711 -3.4.24.16 (o-aminobenzoyl)-ggflrrv-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 2.0 2.0 1 PMID:12199711 -3.4.24.16 (o-aminobenzoyl)-ggflrrvq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.4 1.4 1 PMID:12199711 -3.4.24.16 (o-aminobenzoyl)-ggflrryq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.3 0.25 2 PMID:12199711 -3.4.24.16 (o-aminobenzoyl)-ghspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.95 0.95 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gispfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 2.6 2.6 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-glspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.2 6.2 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gnspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.3 1.3 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gpspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 2.2 2.2 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gqspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.9 1.9 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-grspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 5.4 5.4 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-gsspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 2.0 2.0 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-hfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.2 1.2 1 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-ifspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.45 0.25 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-kprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.0 4.3149999999999995 2 PMID:11355859 -3.4.24.16 (o-aminobenzoyl)-lfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.35 0.24 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-lyenkprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 3.8 3.8 1 PMID:11355859 -3.4.24.16 (o-aminobenzoyl)-naprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.00697 0.00697 1 PMID:11355859 -3.4.24.16 (o-aminobenzoyl)-nfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 1.0 0.58 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-nkarrpq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.00576 0.00576 1 PMID:11355859 -3.4.24.16 (o-aminobenzoyl)-nkparpq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.00123 0.00123 1 PMID:11355859 -3.4.24.16 (o-aminobenzoyl)-nkprapq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.014 0.014 1 PMID:11355859 -3.4.24.16 (o-aminobenzoyl)-nkprraq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.00124 0.00124 1 PMID:11355859 -3.4.24.16 (o-aminobenzoyl)-nkprrpq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 7.0 7.0 1 PMID:11355859 -3.4.24.16 (o-aminobenzoyl)-qfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.39 0.255 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-rfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 0.27 0.14500000000000002 2 PMID:11284698 -3.4.24.16 (o-aminobenzoyl)-sfspfrq-(n-(2,4-dinitrophenyl)ethylenediamine) sus scrofa 6.08 0.77 3 PMID:11284698 -3.4.24.16 2-aminobenzoyl-gfspfrq-(n-2,4-dinitrophenyl)ethylenediamine rattus norvegicus 0.3 0.3 1 PMID:17313369 -3.4.24.16 abz-gfsafrqeddnp rattus norvegicus 2.6 2.6 1 PMID:17313369 -3.4.24.16 abz-gfsefrqeddnp rattus norvegicus 0.7 0.7 1 PMID:17313369 -3.4.24.16 abz-gfsffrqeddnp rattus norvegicus 3.4 3.4 1 PMID:17313369 -3.4.24.16 abz-gfshfrqeddnp rattus norvegicus 2.5 2.5 1 PMID:17313369 -3.4.24.16 abz-gfsifrqeddnp rattus norvegicus 0.2 0.2 1 PMID:17313369 -3.4.24.16 abz-gfslfrqeddnp rattus norvegicus 3.5 3.5 1 PMID:17313369 -3.4.24.16 abz-gfsqfrqeddnp rattus norvegicus 3.6 3.6 1 PMID:17313369 -3.4.24.16 abz-gfsrfrqeddnp rattus norvegicus 4.8 4.8 1 PMID:17313369 -3.4.24.16 abz-gfssfrqeddnp rattus norvegicus 7.5 7.5 1 PMID:17313369 -3.4.24.16 abz-gfswfrqeddnp rattus norvegicus 0.3 0.3 1 PMID:17313369 -3.4.24.16 abz-gfsyfrqeddnp rattus norvegicus 1.0 1.0 1 PMID:17313369 -3.4.24.16 neurotensin rattus norvegicus 5.0 5.0 1 PMID:17251185 -3.4.24.16 tyr-gly-gly-phe-leu-arg rattus norvegicus 0.827 0.827 1 PMID:7730308 -3.4.24.16 tyr-gly-gly-phe-leu-arg-arg rattus norvegicus 1.94 1.94 1 PMID:7730308 -3.4.24.16 tyr-gly-gly-phe-leu-arg-arg-ile rattus norvegicus 2.52 2.52 1 PMID:7730308 -3.4.24.16 tyr-gly-gly-phe-leu-arg-arg-ile-arg rattus norvegicus 1.5 1.5 1 PMID:7730308 -3.4.24.17 (7-methoxycoumarin-4-yl)acetyl-arg-pro-lys-pro-tyr-ala-norvaline-trp-met-lys(2,4-dinitrophenyl)-nh2 homo sapiens 3.95 3.95 1 PMID:8063713 -3.4.24.17 (7-methoxycoumarin-4-yl)acetyl-arg-pro-lys-pro-val-glu-norvaline-trp-arg-lys(2,4-dinitrophenyl)-nh2 homo sapiens 5.4 5.4 1 PMID:7674937;PMID:8063713 -3.4.24.17 (7-methoxycoumarin-4-yl)acetyl-pro-lys-pro-gln-gln-phe-phe-gly-leu-lys-(2,4-dinitrophenyl)-gly homo sapiens 0.53 0.53 1 PMID:8063713 -3.4.24.17 2,4-dinitrophenyl-pro-tyr-ala-tyr-trp-met-arg-nh2 homo sapiens 0.24 0.24 1 PMID:7674937 -3.4.24.17 acetyl-pro-leu-gly-thioester-leu-leu-gly ethyl ester homo sapiens 2.12 2.12 1 PMID:2845958 -3.4.24.17 arg-pro-lys-pro-gln-gln-phe-phe-gly-leu-nle-nh2 homo sapiens 1.35 1.125 2 PMID:1581308 -3.4.24.17 beta-casein homo sapiens 0.088 0.0865 2 PMID:9101722 -3.4.24.18 2-aminobenzoyl-arg-gly-pro-phe-ser-pro-(4-nitro)phe-arg mus musculus 1.1 1.1 1 PMID:7674930;PMID:8161197 -3.4.24.18 2-aminobenzoyl-arg-hyp-gly-phe-ser-pro-(4-nitro)phe-arg mus musculus 26.7 26.7 1 PMID:7674930;PMID:8161197 -3.4.24.18 2-aminobenzoyl-arg-pro-gly-ala-ser-pro-(4-nitro)phe-arg mus musculus 98.5 98.5 1 PMID:7674930;PMID:8161197 -3.4.24.18 2-aminobenzoyl-arg-pro-gly-glu-ser-pro-(4-nitro)phe-arg mus musculus 4.9 4.9 1 PMID:7674930;PMID:8161197 -3.4.24.18 2-aminobenzoyl-arg-pro-gly-leu-ser-pro-(4-nitro)phe-arg mus musculus 12.0 12.0 1 PMID:7674930;PMID:8161197 -3.4.24.18 2-aminobenzoyl-arg-pro-gly-lys-ser-pro-(4-nitro)phe-arg mus musculus 2.4 2.4 1 PMID:7674930;PMID:8161197 -3.4.24.18 2-aminobenzoyl-arg-pro-ile-phe-ser-pro-(4-nitro)phe-arg mus musculus 133.0 133.0 1 PMID:7674930;PMID:8161197 -3.4.24.18 alpha-msh homo sapiens 16.5 16.5 1 PMID:17976009 -3.4.24.18 alpha-msh mus musculus 45.4 45.4 1 PMID:17976009 -3.4.24.18 arg-pro-pro-gly-(4-nitro)phe-ala-pro-phe-arg mus musculus 51.5 51.5 1 PMID:7674930;PMID:8161197 -3.4.24.18 arg-pro-pro-gly-(4-nitro)phe-arg-pro-phe-arg mus musculus 19.6 19.6 1 PMID:7674930;PMID:8161197 -3.4.24.18 arg-pro-pro-gly-(4-nitro)phe-lys-pro-phe-arg mus musculus 5.0 5.0 1 PMID:7674930;PMID:8161197 -3.4.24.18 arg-pro-pro-gly-(4-nitro)phe-phe-pro-phe-arg mus musculus 7.6 7.6 1 PMID:7674930;PMID:8161197 -3.4.24.18 arg-pro-pro-gly-(4-nitro)phe-ser-pro-phe-arg mus musculus 40.9 40.9 1 PMID:7674930;PMID:8161197 -3.4.24.18 bradykinin homo sapiens 3.7 3.7 1 PMID:17976009 -3.4.24.18 bradykinin mus musculus 22.0 19.3 2 PMID:11278902;PMID:17976009 -3.4.24.18 bradykinin rattus norvegicus 13.4 13.4 1 PMID:12437103 -3.4.24.18 cholecystokinin 8-sulfate mus musculus 8.6 8.6 1 PMID:12888571 -3.4.24.18 gastrin homo sapiens 0.4 0.4 1 PMID:17976009 -3.4.24.18 glucagon mus musculus 17.4 17.4 1 PMID:11278902 -3.4.24.18 kkgyvadap-4-nitroanilide homo sapiens 1.0 1.0 2 PMID:30098994 -3.4.24.18 orcokinin homo sapiens 6.3 6.3 1 PMID:17976009 -3.4.24.18 parathyphoid hormone 12-34 homo sapiens 4.6 4.6 1 PMID:17976009 -3.4.24.18 protein grp homo sapiens 19.6 19.6 1 PMID:17976009 -3.4.24.18 protein grp mus musculus 24.6 24.6 1 PMID:17976009 -3.4.24.18 protein lhrh homo sapiens 5.1 5.1 1 PMID:17976009 -3.4.24.18 protein lhrh mus musculus 39.4 39.4 1 PMID:17976009 -3.4.24.18 protein pth12-34 mus musculus 10.5 10.5 1 PMID:17976009 -3.4.24.18 secretin homo sapiens 8.4 8.4 1 PMID:17976009 -3.4.24.18 secretin mus musculus 11.8 8.100000000000001 2 PMID:11278902;PMID:17976009 -3.4.24.18 substance p homo sapiens 5.2 5.2 1 PMID:17976009 -3.4.24.18 substance p mus musculus 12.1 12.1 1 PMID:17976009 -3.4.24.18 valosin mus musculus 18.8 18.8 1 PMID:11278902 -3.4.24.19 procollagen type i homo sapiens 0.059 0.016 5 PMID:15834133;PMID:27872885 -3.4.24.20 2,4-dinitrophenyl-adklsw grifola frondosa 1.3 1.3 1 PMID:9644258 -3.4.24.20 2,4-dinitrophenyl-apklsw grifola frondosa 5.5 5.5 1 PMID:9644258 -3.4.24.20 2,4-dinitrophenyl-arklsw grifola frondosa 54.7 54.7 1 PMID:9644258 -3.4.24.20 2,4-dinitrophenyl-atkdsw grifola frondosa 0.25 0.25 1 PMID:9644258 -3.4.24.20 2,4-dinitrophenyl-atklstsw grifola frondosa 17.6 9.295 2 PMID:9644258 -3.4.24.20 2,4-dinitrophenyl-atklsw grifola frondosa 3.0 3.0 1 PMID:9644258 -3.4.24.20 2,4-dinitrophenyl-atkrsw grifola frondosa 3.7 3.7 1 PMID:9644258 -3.4.24.20 2,4-dinitrophenyl-dadklsw grifola frondosa 0.12 0.12 1 PMID:9644258 -3.4.24.20 2,4-dinitrophenyl-datklsw grifola frondosa 5.1 5.1 1 PMID:9644258 -3.4.24.20 2,4-dinitrophenyl-statklsw grifola frondosa 21.0 21.0 1 PMID:9644258 -3.4.24.20 saqkmrs armillaria mellea 0.64 0.64 1 PMID:26572161 -3.4.24.20 saqkmvr armillaria mellea 1.51 1.51 1 PMID:26572161 -3.4.24.20 saqkmvs armillaria mellea 1.0 1.0 1 PMID:26572161 -3.4.24.20 saqkrvs armillaria mellea 0.26 0.26 1 PMID:26572161 -3.4.24.21 2-aminobenzoyl-arg-gly-pro-phe-ser-pro-(4-nitro)phe-arg astacus astacus 7.1 7.1 1 PMID:8161197 -3.4.24.21 2-aminobenzoyl-arg-hyp-gly-phe-ser-pro-(4-nitro)phe-arg astacus astacus 15.1 15.1 1 PMID:8161197 -3.4.24.21 2-aminobenzoyl-arg-pro-gly-ala-ser-pro-(4-nitro)phe-arg astacus astacus 44.4 44.4 1 PMID:8161197 -3.4.24.21 2-aminobenzoyl-arg-pro-gly-glu-ser-pro-4-nitrophenylalanine-arg astacus astacus 2.8 2.8 1 PMID:8161197 -3.4.24.21 2-aminobenzoyl-arg-pro-gly-leu-ser-pro-(4-nitro)phe-arg astacus astacus 14.3 14.3 1 PMID:8161197 -3.4.24.21 2-aminobenzoyl-arg-pro-gly-lys-ser-pro-(4-nitro)phe-arg astacus astacus 3.6 3.6 1 PMID:8161197 -3.4.24.21 2-aminobenzoyl-arg-pro-ile-phe-ser-pro-(4-nitro)phe-arg astacus astacus 78.4 78.4 1 PMID:8161197 -3.4.24.21 arg-pro-pro-gly-(4-nitro)phe-ala-pro-phe-arg astacus astacus 834.0 834.0 1 PMID:8161197 -3.4.24.21 arg-pro-pro-gly-(4-nitro)phe-arg-pro-phe-arg astacus astacus 0.002 0.002 1 PMID:8161197 -3.4.24.21 arg-pro-pro-gly-(4-nitro)phe-lys-pro-phe-arg astacus astacus 0.001 0.001 1 PMID:8161197 -3.4.24.21 arg-pro-pro-gly-(4-nitro)phe-phe-pro-phe-arg astacus astacus 0.004 0.004 1 PMID:8161197 -3.4.24.21 arg-pro-pro-gly-(4-nitro)phe-ser-pro-phe-arg astacus astacus 78.7 78.7 1 PMID:8161197 -3.4.24.21 azocasein steinernema carpocapsae 27.9 27.9 1 PMID:20670659 -3.4.24.21 dansyl-ala-ala-arg-ala-pro-leu-val astacus astacus 200.0 200.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-arg-ala-pro-leu astacus astacus 0.035 0.035 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-gly-arg-arg-ala-pro-leu-gly astacus astacus 34.0 34.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-gly-arg-arg-ala-ser-leu-gly astacus astacus 0.7 0.7 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-gly-gly-arg-ala-pro-trp-val astacus astacus 20.0 20.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-gly-lys-arg-ala-pro-leu-val astacus astacus 2.3 2.3 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-gly-lys-arg-ala-pro-trp-val astacus astacus 2.2 2.2 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-gly-lys-asn-ala-pro-leu-val astacus astacus 56.0 47.5 2 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-gly-lys-tyr-ala-pro-trp-val astacus astacus 40.0 40.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-gly-pro-arg-ala-pro-leu-val astacus astacus 20.0 20.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-his-his-leu-lys-arg-ala-pro-trp-val astacus astacus 310.0 310.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-leu-arg-arg-ala-pro-leu-gly astacus astacus 130.0 130.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-leu-arg-arg-ala-ser-leu-gly astacus astacus 2.7 2.7 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-leu-lys-arg-ala-pro-leu astacus astacus 43.0 43.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-leu-lys-arg-ala-pro-leu-val astacus astacus 120.0 120.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-leu-lys-arg-ala-pro-trp-val astacus astacus 210.0 210.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-leu-lys-asn-ala-pro-leu-val astacus astacus 180.0 180.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-leu-lys-lys-ala-pro-trp-val astacus astacus 210.0 210.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-leu-lys-tyr-ala-pro-trp-val astacus astacus 67.0 67.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-lys-arg-ala-pro-leu astacus astacus 40.0 40.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-pro-lys-arg-ala-pro-trp-val astacus astacus 380.0 380.0 1 PMID:2261483;PMID:7674929 -3.4.24.21 dansyl-val-lys-arg-ala-pro-trp-val astacus astacus 190.0 190.0 1 PMID:2261483;PMID:7674929 -3.4.24.22 (7-methoxycoumarin-4-yl)acetyl-arg-pro-lys-pro-val-glu-norvaline-trp-arg-lys(2,4-dinitrophenyl)-nh2 homo sapiens 3.8 3.8 1 PMID:7674937 -3.4.24.23 (7-methoxycoumarin-4-yl)acetyl-lpro-l-leu-gly-l-leu-[n3-(2,4-dinitrophenyl)-l-2,3-diaminopropionyl]-l-ala-l-arg-nh2 homo sapiens 6.43 6.43 1 PMID:21593056 -3.4.24.23 2,4-dinitrophenyl-arg-pro-leu-ala-leu-trp-arg-ser homo sapiens 5.0 5.0 1 PMID:7503560 -3.4.24.23 2,4-dinitrophenyl-pro-leu-gly-leu-trp-ala-d-arg homo sapiens 3.5 3.5 1 PMID:7503560 -3.4.24.23 dansyl-plalwar homo sapiens 2.7 2.7 1 PMID:9398337 -3.4.24.23 gly-pro-gln-ala-ile-ala-gly-gln homo sapiens 0.472 0.472 1 PMID:8390857 -3.4.24.23 gly-pro-gln-gly-ile-ala-gly-gln homo sapiens 0.222 0.222 1 PMID:8390857 -3.4.24.23 gly-pro-gln-gly-ile-ala-met-gln homo sapiens 1.17 1.17 1 PMID:8390857 -3.4.24.23 gly-pro-gln-gly-leu-ala-gly-gln homo sapiens 2.47 2.47 1 PMID:8390857 -3.4.24.23 gly-pro-met-gly-ile-ala-gly-gln homo sapiens 1.92 1.92 1 PMID:8390857 -3.4.24.24 ac-pro-leu-gly-[2-mercapto-4-methylpentanoyl]-leu-gly-oet homo sapiens 19.5 18.1 2 PMID:12509986 -3.4.24.24 acetyl-pro-leu-gly-thioester-leu-leu-gly ethyl ester homo sapiens 1.6 1.6 1 PMID:7718575 -3.4.24.24 alpha1(v)436-447 fthp homo sapiens 0.0616 0.0616 1 PMID:12642591 -3.4.24.24 dnp-pro-beta-cyclohexyl-ala-gly-cys(me)-his-ala-lys(n-me-abz)-nh2 homo sapiens 5.4 5.050000000000001 2 PMID:12509986 -3.4.24.24 fibrinogen homo sapiens 36.4 36.4 1 PMID:17087661 -3.4.24.24 fthp-3 homo sapiens 0.017 0.017 1 PMID:12642591 -3.4.24.24 gly-pro-gln-gly-ile-ala-gly-gln homo sapiens 2.69 2.69 1 PMID:8390857 -3.4.24.24 gly-pro-gln-gly-ile-ala-ser-gln homo sapiens 2.0 2.0 1 PMID:8390857 -3.4.24.24 gly-pro-gln-gly-ile-phe-gly-gln homo sapiens 3.33 3.33 1 PMID:8390857 -3.4.24.24 gly-pro-gln-gly-ile-trp-gly-gln homo sapiens 0.612 0.612 1 PMID:8390857 -3.4.24.24 mca-pro-leu-gly-leu-dap-ala-arg-nh2 homo sapiens 1.7 1.15 2 PMID:12509986 -3.4.24.24 moacplgla2pr(dnp)-ar-nh2 homo sapiens 6.0 3.18 3 PMID:9368077 -3.4.24.24 peptide a13 homo sapiens 105.0 105.0 2 PMID:11694539;PMID:12591933 -3.4.24.24 peptide a13p homo sapiens 204.0 204.0 1 PMID:11694539 -3.4.24.24 peptide a13r homo sapiens 8.0 8.0 2 PMID:11694539;PMID:12591933 -3.4.24.24 peptide a21 homo sapiens 124.0 124.0 1 PMID:11694539 -3.4.24.24 peptide a21a homo sapiens 601.0 601.0 1 PMID:11694539 -3.4.24.24 peptide a3 homo sapiens 400.0 400.0 2 PMID:11694539;PMID:12591933 -3.4.24.24 peptide a34 homo sapiens 202.0 202.0 2 PMID:11694539;PMID:12591933 -3.4.24.24 peptide b37 homo sapiens 353.0 353.0 1 PMID:11694539 -3.4.24.24 peptide b49 homo sapiens 510.0 510.0 1 PMID:11694539 -3.4.24.24 peptide b74 homo sapiens 622.0 622.0 2 PMID:11694539;PMID:12591933 -3.4.24.24 peptide b74p homo sapiens 264.0 264.0 1 PMID:11694539 -3.4.24.24 peptide b74r homo sapiens 61.0 61.0 1 PMID:11694539 -3.4.24.24 peptide c9 homo sapiens 740.0 740.0 2 PMID:11694539;PMID:12591933 -3.4.24.24 type i collagen gallus gallus 0.0045 0.0045 1 PMID:7890717 -3.4.24.24 type i collagen homo sapiens 0.0045 0.0045 1 PMID:12642591 -3.4.24.24 type v collagen homo sapiens 0.0022 0.0022 1 PMID:12642591 -3.4.24.24 vitronectin of mw 65000 and 75000 homo sapiens 0.00167 0.00167 1 PMID:7544295 -3.4.24.25 benzyloxycarbonyl-gly-ile-nh2 vibrio proteolyticus 2.5 2.5 1 PMID:7000005 -3.4.24.25 benzyloxycarbonyl-gly-leu-nh2 vibrio proteolyticus 25.0 25.0 1 PMID:2276 -3.4.24.25 benzyloxycarbonyl-gly-norvaline-nh2 vibrio proteolyticus 4.0 4.0 1 PMID:7000005 -3.4.24.25 benzyloxycarbonyl-gly-phe-gly-nh2 vibrio proteolyticus 1150.0 1150.0 1 PMID:3123480 -3.4.24.25 benzyloxycarbonyl-gly-phe-nh2 vibrio proteolyticus 584.0 292.2 2 PMID:2276;PMID:7000005 -3.4.24.25 benzyloxycarbonyl-gly-tyr vibrio proteolyticus 38.0 38.0 1 PMID:2276 -3.4.24.25 benzyloxycarbonyl-gly-tyr-nh2 vibrio proteolyticus 0.5 0.5 1 PMID:7000005 -3.4.24.26 2-aminobenzoyl-ala-gly-leu-ala 4-nitrobenzylamide pseudomonas aeruginosa 100.0 100.0 1 PMID:6767718;PMID:7674924 -3.4.24.26 3-(2-furyl)acryloyl-glycyl-l-phenylalanyl-l-phenylalanine pseudomonas aeruginosa 240.0 240.0 1 PMID:3142360 -3.4.24.26 azocasein pseudomonas aeruginosa 1.27 1.27 1 PMID:30837358 -3.4.24.26 benzyloxycarbonyl-ala-leu-ala pseudomonas aeruginosa 1100.0 1100.0 1 PMID:6767718 -3.4.24.26 benzyloxycarbonyl-gly-leu-ala pseudomonas aeruginosa 945.0 945.0 1 * -3.4.24.26 benzyloxycarbonyl-gly-leu-gly pseudomonas aeruginosa 46.2 46.2 1 * -3.4.24.26 benzyloxycarbonyl-gly-leu-leu pseudomonas aeruginosa 890.0 890.0 1 * -3.4.24.26 benzyloxycarbonyl-gly-leu-nh2 pseudomonas aeruginosa 23.0 23.0 1 * -3.4.24.26 benzyloxycarbonyl-gly-leu-phe pseudomonas aeruginosa 640.0 640.0 1 * -3.4.24.26 benzyloxycarbonyl-gly-phe-nh2 pseudomonas aeruginosa 47.6 47.6 1 * -3.4.24.26 benzyloxycarbonyl-gly-tyr-nh2 pseudomonas aeruginosa 17.4 17.4 1 * -3.4.24.26 benzyloxycarbonyl-phe-leu-ala pseudomonas aeruginosa 247.0 247.0 1 * -3.4.24.26 carbobenzooxydialanine-leucylalaninamide pseudomonas aeruginosa 406.8 298.4 2 PMID:8660569 -3.4.24.26 carbobenzooxydialanine-phenylalanylalaninamide pseudomonas aeruginosa 1032.0 1032.0 1 PMID:8660569 -3.4.24.26 carbobenzooxydialanine-tyrosylalaninamide pseudomonas aeruginosa 338.2 338.2 1 PMID:8660569 -3.4.24.26 dabsyl-ala-ala-phe-ala-edans pseudomonas aeruginosa 618.0 618.0 1 PMID:17553454 -3.4.24.26 dialanine-phenylalanylalaninamide pseudomonas aeruginosa 540.0 540.0 1 PMID:8660569 -3.4.24.26 furylacryloyl-ala-leu-ala pseudomonas aeruginosa 144.0 144.0 1 PMID:2495818 -3.4.24.26 furylacryloyl-ala-leu-gly pseudomonas aeruginosa 34.0 34.0 1 PMID:2495818 -3.4.24.26 furylacryloyl-gly-leu-ala pseudomonas aeruginosa 95.0 95.0 1 PMID:2495818 -3.4.24.26 furylacryloyl-gly-leu-gly pseudomonas aeruginosa 7.0 7.0 1 PMID:2495818 -3.4.24.26 pentaalanine pseudomonas aeruginosa 420.0 322.2 2 PMID:2495818;PMID:8660569 -3.4.24.26 tetraalanine pseudomonas aeruginosa 250.0 178.0 2 PMID:2495818;PMID:8660569 -3.4.24.26 trialanine-phenylalanylalanine pseudomonas aeruginosa 769.6 769.6 1 PMID:8660569 -3.4.24.27 (7-methoxycoumarin-4yl) acetyl-l-pro-l-leu-gly-l-leu-[n3-(2,4-dinitrophenyl)-l-2,3-diamino-propionyl]-l-ala-l-arg-nh2 bacillus thermoproteolyticus 2.36 2.36 1 PMID:19720529 -3.4.24.27 (europium(iii) complex of a modified terpyridine)-k1k2k2gfsak2k-black hole quencher 2 bacillus thermoproteolyticus 2.6 2.6 1 PMID:19720529 -3.4.24.27 5,6-carboxyfluorescein-paglac(alexa fluor 647)-nh2 geobacillus stearothermophilus 0.7 0.7 1 PMID:31458650 -3.4.24.27 5,6-carboxyfluorescein-paglac(cy5)-nh2 geobacillus stearothermophilus 0.37 0.37 1 PMID:31458650 -3.4.24.27 5,6-carboxyfluorescein-psvaglaggc(alexa fluor 647)-nh2 geobacillus stearothermophilus 5.7 5.7 1 PMID:31458650 -3.4.24.27 5,6-carboxyfluorescein-psvaglaggc(cy5)-nh2 geobacillus stearothermophilus 7.82 7.82 1 PMID:31458650 -3.4.24.27 5,6-carboxyfluorescein-pvaglagc(cy5)-nh2 geobacillus stearothermophilus 2.96 2.96 1 PMID:31458650 -3.4.24.27 benzyloxycarbonyl-(4-nitro)phe-leu-ala bacillus thermoproteolyticus 951.0 951.0 1 PMID:687598 -3.4.24.27 benzyloxycarbonyl-gly-phe-leu-ala bacillus thermoproteolyticus 968.0 968.0 1 PMID:687598 -3.4.24.27 benzyloxycarbonyl-phe-leu-ala bacillus thermoproteolyticus 605.0 605.0 1 PMID:687598 -3.4.24.27 dansyl-gly-phe-ala bacillus thermoproteolyticus 1.7 1.7 1 PMID:8204585 -3.4.24.27 gfa bacillus thermoproteolyticus 0.076 0.068 2 PMID:9003446 -3.4.24.27 gfl bacillus thermoproteolyticus 0.045 0.0195 4 PMID:9003446 -3.4.24.27 gfs bacillus thermoproteolyticus 0.05 0.0425 2 PMID:9003446 -3.4.24.27 gfsa bacillus thermoproteolyticus 6.08 0.3 5 PMID:9003446 -3.4.24.27 l-phenylalanine methyl ester bacillus thermoproteolyticus 1.3 1.3 1 * -3.4.24.27 leucine enkephalin bacillus thermoproteolyticus 1560.0 855.5 4 PMID:9374873;PMID:9827548 -3.4.24.27 n,n'-diboc-dityrosyl-(ile-isoniazid)2 bacillus thermoproteolyticus 0.238 0.238 1 * -3.4.24.27 n,n'-diboc-dityrosyl-(phe-isoniazid)2 bacillus thermoproteolyticus 0.0463 0.0463 1 * -3.4.24.27 n-(benzyloxycarbonyl)-l-phe bacillus thermoproteolyticus 1.69 1.123 2 * -3.4.24.27 n-benzyloxycarbonyl-gly-l-leu amide bacillus sp. (in: firmicutes) 51.67 51.67 1 PMID:22139731 -3.4.24.27 n-benzyloxycarbonyl-l-asp-l-phe-methyl ester bacillus thermoproteolyticus 7.9 7.9 1 PMID:21150094 -3.4.24.27 n-carbobenzoxy-gly-l-leu-nh2 bacillus thermoproteolyticus 51.6 51.6 1 PMID:15115781 -3.4.24.27 n-carbobenzoxy-l-asp-l-phe methyl ester bacillus thermoproteolyticus 5.9 4.05 6 PMID:16169746;PMID:17869197;PMID:17875473;PMID:20214932 -3.4.24.27 n-carbobenzoxy-l-asp-l-phe-methyl ester bacillus thermoproteolyticus 9.5 9.5 1 * -3.4.24.27 n-carbobenzoxy-l-aspartic acid bacillus thermoproteolyticus 1.3 1.3 1 * -3.4.24.27 n-carbobenzoxy-l-aspartyl-l-phenylalanine methyl ester bacillus thermoproteolyticus 7.7 7.7 1 PMID:22648563 -3.4.24.27 thermolysin bacillus thermoproteolyticus 3.5e-06 2.9e-06 2 PMID:33727669 -3.4.24.28 3-(2-furylacryloyl)-glycyl-l-leucine amide bacillus subtilis 256.0 256.0 1 * -3.4.24.28 3-(2-furylacryloyl)-l-alanyl-l-phenylalanine amide bacillus subtilis 64.0 64.0 1 * -3.4.24.28 azocasein bacillus intermedius 1210.0 1210.0 1 PMID:21166648 -3.4.24.28 plasminogen priestia megaterium 0.7 0.7 1 PMID:15677446 -3.4.24.3 furylacryloyl-leu-gly-pro-ala clostridium tetani 7.24 5.445 2 PMID:18937627 -3.4.24.3 furylacryloyl-leu-gly-pro-ala hathewaya histolytica 15.9 6.8549999999999995 4 PMID:18937627 -3.4.24.3 gelatin bacillus cereus 7.7 7.7 1 PMID:33603127 -3.4.24.3 gelatin hathewaya histolytica 9.9 9.9 1 PMID:33603127 -3.4.24.34 (7-methoxycoumarin-4-yl)acetyl-pro-cyclohexylalanine-gly-norvaline-his-ala-arg-nh2 homo sapiens 570.0 248.0 4 PMID:10749856 -3.4.24.34 (7-methoxycoumarin-4-yl)acetyl-pro-leu-gly-leu-diaminopropionyl-ala-arg-nh2 homo sapiens 562.0 244.0 8 PMID:10749856;PMID:11023917 -3.4.24.34 bovine collagen i homo sapiens 1120.0 4.75 5 PMID:10749856;PMID:11953425 -3.4.24.34 guinea pig collagen type i homo sapiens 0.00161 0.00161 1 PMID:3038863 -3.4.24.34 human collagen type i homo sapiens 0.00178 0.00178 1 PMID:3038863 -3.4.24.34 human collagen type ii homo sapiens 0.00065 0.00065 1 PMID:3038863 -3.4.24.34 human collagen type iii homo sapiens 0.000233 0.000233 1 PMID:3038863 -3.4.24.35 (7-methoxycoumaryl-4yl)acetylplgla2pr(2,4-dinitrophenol)-ar-nh2 homo sapiens 8.67 4.36 4 PMID:10644727 -3.4.24.35 sgfgsrylta mus musculus 11.0 11.0 1 PMID:11279151 -3.4.24.35 sgkgprqita mus musculus 703.0 703.0 1 PMID:11279151 -3.4.24.35 sgkiprrlta mus musculus 224.0 224.0 1 PMID:11279151 -3.4.24.35 sgkiprtata mus musculus 9.4 9.4 1 PMID:11279151 -3.4.24.35 sgkiprtlta mus musculus 86.4 86.4 1 PMID:11279151 -3.4.24.35 sglkalmita mus musculus 30.0 30.0 1 PMID:11279151 -3.4.24.35 sglrpaksta mus musculus 78.0 78.0 1 PMID:11279151 -3.4.24.35 sgplfysvta mus musculus 20.0 20.0 1 PMID:11279151 -3.4.24.35 sgpravstta mus musculus 178.0 178.0 1 PMID:11279151 -3.4.24.35 sgqphyltta mus musculus 9.0 9.0 1 PMID:11279151 -3.4.24.35 stromelysin 1 homo sapiens 0.0019 0.001155 2 PMID:10644727 -3.4.24.35 vitronectin of mw 65000 homo sapiens 0.0005 0.0005 1 PMID:7544295 -3.4.24.35 vitronectin of mw 75000 homo sapiens 0.000333 0.000333 1 PMID:7544295 -3.4.24.36 casein leishmania donovani donovani 12.0 12.0 1 PMID:20678540 -3.4.24.37 acetyl-ala-ala-pro-ala 4-nitroanilide saccharomyces cerevisiae 6000.0 6000.0 1 PMID:3886641 -3.4.24.37 acetyl-ala-ala-pro-phe 4-nitroanilide saccharomyces cerevisiae 38000.0 38000.0 1 PMID:3886641 -3.4.24.37 benzoyl-pro-phe-arg 4-nitroanilide saccharomyces cerevisiae 1500.0 1500.0 1 PMID:3886641 -3.4.24.37 methoxysuccinyl-ala-ala-pro-met 4-nitroanilide saccharomyces cerevisiae 38000.0 38000.0 1 PMID:3886641 -3.4.24.39 n-butoxycarbonyl-arginyl-valyl-arginyl-arginyl-4-methylcoumarin-7-amide aspergillus oryzae 0.022 0.0195 2 PMID:12728984 -3.4.24.39 n-butoxycarbonyl-leu-arg-arg-4-methylcoumarin-7-amide aspergillus oryzae 0.0045 0.0031 2 PMID:12728984 -3.4.24.39 n-butoxycarbonyl-leu-lys-arg-4-methylcoumarin-7-amide aspergillus oryzae 0.009 0.0062499999999999995 2 PMID:12728984 -3.4.24.39 pyr-arg-thr-lys-arg-4-methylcoumarin-7-amide aspergillus oryzae 0.0022 0.00151 2 PMID:12728984 -3.4.24.39 z-arg-arg-4-methylcoumarin-7-amide aspergillus oryzae 0.0009 0.000775 2 PMID:12728984 -3.4.24.40 2-aminobenzoyl-klcsskq-n-(2,4-dinitrophenyl)ethylenediamine thermoascus aurantiacus 0.15 0.15 1 PMID:19746980 -3.4.24.40 2-aminobenzoyl-klksskq-n-(2,4-dinitrophenyl)ethylenediamine thermoascus aurantiacus 0.19 0.19 1 PMID:19746980 -3.4.24.40 2-aminobenzoyl-klrsskq-n-(2,4-dinitrophenyl)ethylenediamine thermoascus aurantiacus 0.52 0.52 1 PMID:19746980 -3.4.24.40 angiotensin i pseudomonas aeruginosa 2.94 2.23 2 PMID:9748654 -3.4.24.40 angiotensin ii pseudomonas aeruginosa 6.08 3.305 2 PMID:9748654 -3.4.24.40 azocasein pseudomonas sp. 0.045 0.045 1 * -3.4.24.40 benzyloxycarbonyl-l-arg-l-arg-4-nitroanilide pseudomonas aeruginosa 0.026 0.01 3 PMID:16221305 -3.4.24.40 o-aminobenzoyl-kdrfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 1.3 1.3 1 * -3.4.24.40 o-aminobenzoyl-kfrfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 20.67 20.67 1 * -3.4.24.40 o-aminobenzoyl-kgrfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 9.52 9.52 1 * -3.4.24.40 o-aminobenzoyl-khrfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 32.5 32.5 1 * -3.4.24.40 o-aminobenzoyl-klafskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 29.2 29.2 1 * -3.4.24.40 o-aminobenzoyl-kldfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 13.0 13.0 1 * -3.4.24.40 o-aminobenzoyl-klefskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 22.0 22.0 1 * -3.4.24.40 o-aminobenzoyl-klffskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 44.2 44.2 1 * -3.4.24.40 o-aminobenzoyl-klgfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 109.2 109.2 1 * -3.4.24.40 o-aminobenzoyl-klhfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 29.9 29.9 1 * -3.4.24.40 o-aminobenzoyl-klkfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 21.9 21.9 1 * -3.4.24.40 o-aminobenzoyl-kllfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 10.8 10.8 1 * -3.4.24.40 o-aminobenzoyl-klmfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 70.1 70.1 1 * -3.4.24.40 o-aminobenzoyl-klnfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 17.0 17.0 1 * -3.4.24.40 o-aminobenzoyl-klpfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 6.3 6.3 1 * -3.4.24.40 o-aminobenzoyl-klqfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 24.4 24.4 1 * -3.4.24.40 o-aminobenzoyl-klraskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 74.15 74.15 1 * -3.4.24.40 o-aminobenzoyl-klrdskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 0.57 0.57 1 * -3.4.24.40 o-aminobenzoyl-klrfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 33.4 33.4 1 * -3.4.24.40 o-aminobenzoyl-klrlskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 89.61 89.61 1 * -3.4.24.40 o-aminobenzoyl-klrnskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 52.17 52.17 1 * -3.4.24.40 o-aminobenzoyl-klrrskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 2.82 2.82 1 * -3.4.24.40 o-aminobenzoyl-klrsskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 35.07 35.07 1 * -3.4.24.40 o-aminobenzoyl-klsfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 63.2 63.2 1 * -3.4.24.40 o-aminobenzoyl-kltfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 2.2 2.2 1 * -3.4.24.40 o-aminobenzoyl-klwfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 6.7 6.7 1 * -3.4.24.40 o-aminobenzoyl-klyfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 5.0 5.0 1 * -3.4.24.40 o-aminobenzoyl-knrfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 28.19 28.19 1 * -3.4.24.40 o-aminobenzoyl-kqrfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 40.41 40.41 1 * -3.4.24.40 o-aminobenzoyl-krrfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 7.92 7.92 1 * -3.4.24.40 o-aminobenzoyl-ksrfskq-(n-(2,4-dinitrophenyl)-ethylenediamine) serratia proteamaculans 14.43 14.43 1 * -3.4.24.40 peptide 6a pseudomonas aeruginosa 0.038 0.038 1 PMID:9748654 -3.4.24.40 substance p 1-7 pseudomonas aeruginosa 33.0 33.0 1 PMID:9748654 -3.4.24.40 substance p 1-9 pseudomonas aeruginosa 56.0 56.0 1 PMID:9748654 -3.4.24.40 substance p 7-11 pseudomonas aeruginosa 0.08 0.08 1 PMID:9748654 -3.4.24.40 substance p 8-11 pseudomonas aeruginosa 0.02 0.02 1 PMID:9748654 -3.4.24.40 substance p(free acid) pseudomonas aeruginosa 160.0 160.0 1 PMID:9748654 -3.4.24.41 oxidized insulin b-chain crotalus atrox 1.02 0.132 5 PMID:3060135 -3.4.24.44 dimethylcasein crotalus atrox 0.217 0.192 2 PMID:6351911 -3.4.24.44 oxidized insulin a-chain crotalus atrox 0.06 0.0433 3 PMID:6351911 -3.4.24.55 (7-methoxycoumarin-4-yl)acetyl-nle-ala-val-lys-tyr-leu-asn-ser-(2,4-dinitrophenyl)lys-leu-asp-d-lys escherichia coli 2.9 2.9 1 PMID:7674955 -3.4.24.55 beta-amyloid escherichia coli 2.33 2.33 1 PMID:15502359 -3.4.24.55 beta-endorphin escherichia coli 12.5 12.5 1 PMID:15502359 -3.4.24.55 calcitonin escherichia coli 0.43 0.43 1 PMID:15502359 -3.4.24.55 dynorphin a fragment 1-13 halalkalibacterium halodurans 0.55 0.55 1 PMID:15866516 -3.4.24.55 glucagon escherichia coli 0.05 0.05 1 PMID:7680857 -3.4.24.55 insulin b-chain escherichia coli 2.66 2.66 1 PMID:15502359 -3.4.24.55 insulin b-chain halalkalibacterium halodurans 0.18 0.18 1 PMID:15866516 -3.4.24.55 substance p escherichia coli 0.63 0.63 1 PMID:15502359 -3.4.24.55 vasoactive intestinal peptide escherichia coli 0.9 0.9 1 PMID:15502359 -3.4.24.56 (7-methoxycoumarin-4-yl)acetyl-klvffaedk(dnp)-oh homo sapiens 7.5 7.5 1 PMID:29383861 -3.4.24.56 (7-methoxycoumarin-4-yl)acetyl-nppgfsafk-2,4-dinitrophenyl homo sapiens 0.028 0.028 1 PMID:21185309 -3.4.24.56 (7-methoxycoumarin-4-yl)acetyl-qklvffaedvk(2,4-dinitrophenyl)-oh homo sapiens 0.57 0.57 1 PMID:30004674 -3.4.24.56 (7-methoxycoumarin-4-yl)acetyl-rppgfsafk(2,4-dinitrophenyl)-oh homo sapiens 0.23 0.23 1 PMID:26343304 -3.4.24.56 (7-methoxycoumarin-4-yl)acetyl-vealylvcgek(2,4-dinitrophenyl)-oh homo sapiens 0.198 0.198 1 PMID:30004674 -3.4.24.56 2-aminobenzoyl-ggflrkhgq-(n-(2,4-dinitrophenyl)ethylenediamine) rattus norvegicus 162600.0 162600.0 1 PMID:15749695 -3.4.24.56 7-methoxycoumarin-4-yl-acetyl-rppgfsafk-2,4-dinitrophenyl homo sapiens 6.5 6.5 1 PMID:29383861 -3.4.24.56 abz-ggflrkhgq-eddnp homo sapiens 1.7 0.9199999999999999 2 PMID:21343292;PMID:27982586 -3.4.24.56 abz-ggflrkhgq-eddnp rattus norvegicus 0.086 0.0645 2 PMID:20300529;PMID:22049080 -3.4.24.56 abz-ggflrkhgqeddnp rattus norvegicus 104.0 46.97 4 PMID:17154546 -3.4.24.56 amyloid beta homo sapiens 70.0 70.0 1 PMID:19808678 -3.4.24.56 amyloid beta-peptide 1-40 homo sapiens 0.0022 0.0022 1 PMID:22986058 -3.4.24.56 amyloid beta-peptide 1-42 homo sapiens 0.0004 0.0004 1 PMID:22986058 -3.4.24.56 amyloid beta-peptide1-40 homo sapiens 8.0 8.0 1 PMID:17613531 -3.4.24.56 amyloid beta-protein homo sapiens 0.88 0.525 2 PMID:15850385 -3.4.24.56 amyloid beta1-40 homo sapiens 8.0 8.0 1 PMID:19073193 -3.4.24.56 dabcyl-tyr-glu-val-his-his-gln-lys-leu-val-phe-phe-ala-glu-asp-val-gly-glu(edans)-nh2 homo sapiens 62.7 61.85 2 PMID:19073193 -3.4.24.56 insulin homo sapiens 0.079 0.043 7 PMID:15850385;PMID:20082125;PMID:30305381;PMID:37498802 -3.4.24.56 insulin-like peptide 3 homo sapiens 0.0025 0.0025 1 PMID:20082125 -3.4.24.56 protein anp homo sapiens 10.0 10.0 1 PMID:21098034 -3.4.24.56 protein bnp homo sapiens 0.2 0.2 1 PMID:21098034 -3.4.24.56 protein cnp homo sapiens 20.0 20.0 1 PMID:21098034 -3.4.24.56 protein dnp homo sapiens 0.1 0.1 1 PMID:21098034 -3.4.24.56 somatostatin homo sapiens 0.38 0.38 1 PMID:19073193 -3.4.24.56 urodilatin homo sapiens 2.0 2.0 1 PMID:21098034 -3.4.24.59 abz-fqtkvaak(dnp)-nh2 homo sapiens 0.057 0.057 1 PMID:26082885 -3.4.24.59 abz-frsgqplqnkvqlq-ed(dnp) homo sapiens 0.122 0.122 1 PMID:26082885 -3.4.24.59 abz-fsskttvk(dnp)-nh2 homo sapiens 0.036 0.036 1 PMID:26082885 -3.4.24.59 abz-ikqssllk(dnp)-nh2 homo sapiens 0.055 0.055 1 PMID:26082885 -3.4.24.59 abz-mtaalktk(dnp)-nh2 homo sapiens 0.19 0.19 1 PMID:26082885 -3.4.24.59 abz-nlmkkstk(dnp)-nh2 homo sapiens 0.028 0.028 1 PMID:26082885 -3.4.24.59 abz-qplankvq-ed(dnp) homo sapiens 0.057 0.057 1 PMID:26082885 -3.4.24.59 abz-qplqakvq-ed(dnp) homo sapiens 0.0943 0.0943 1 PMID:26082885 -3.4.24.59 abz-qplqnkvq-ed(dnp) homo sapiens 0.061 0.061 1 PMID:26082885 -3.4.24.59 abz-ttklkaak(dnp)-nh2 homo sapiens 0.07 0.07 1 PMID:26082885 -3.4.24.59 abz-vaaqtktk(dnp)-nh2 homo sapiens 0.05 0.05 1 PMID:26082885 -3.4.24.59 abz-vissrlek(dnp)-nh2 homo sapiens 0.083 0.083 1 PMID:26082885 -3.4.24.59 abz-vrnfrsgqplqnkvq-ed(dnp) homo sapiens 0.223 0.223 1 PMID:26082885 -3.4.24.59 abz-wttggkak(dnp)-nh2 homo sapiens 0.0033 0.0033 1 PMID:26082885 -3.4.24.61 2-aminobenzoyl-gfspfrssrqed(2,4-dinitrophenyl) mus musculus 7.68 4.095 2 PMID:12590613 -3.4.24.61 2-aminobenzoyl-ggalrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 3.88 3.88 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfarkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 1.08 1.08 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggffrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 2.83 2.83 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfhrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 6.9 6.9 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfikkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 0.198 0.198 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfikrvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 12.09 12.09 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfirkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 1.23 1.225 2 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfirrvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 15.73 15.73 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfirrvgq-n-(2,4-dinitrophenyl)ethylenediamine mus musculus 5.03 4.165 2 PMID:12590613 -3.4.24.61 2-aminobenzoyl-ggflkkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 2.16 2.16 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggflkrvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 9.75 9.75 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggflrkagq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 2.04 2.04 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggflrkdgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 0.24 0.24 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggflrkfgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 2.94 2.94 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggflrkhgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 13.69 13.69 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggflrkigq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 2.04 2.04 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggflrklgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 1.74 1.74 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggflrkmgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 2.77 2.77 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggflrkngq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 1.59 1.59 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggflrksgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 4.65 4.65 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggflrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 2.48 2.48 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggflrkwgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 5.61 5.61 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggflrrvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 9.92 9.92 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfmrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 4.86 4.86 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfnrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 1.08 1.08 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfsrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 0.353 0.353 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfvrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 0.41 0.41 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfwrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 0.705 0.705 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfykkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 0.187 0.187 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfykrvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 0.405 0.405 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfyrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 2.63 2.61 2 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggfyrrvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 18.99 18.99 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-gghlrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 4.36 4.36 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggilrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 4.84 4.84 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggllrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 5.83 5.83 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggmlrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 7.84 7.84 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggnlrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 0.953 0.953 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggslrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 8.53 8.53 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggvlrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 3.24 3.24 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggwlrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 4.95 4.95 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-ggylrkvgq-ethylenediamine-2,4-dinitrophenyl rattus norvegicus 1.85 1.85 1 PMID:10764809 -3.4.24.61 2-aminobenzoyl-mislmkrpqed(2,4-dinitrophenyl) mus musculus 9.48 5.7250000000000005 2 PMID:12590613 -3.4.24.61 2-aminobenzoyl-tplvtlx1x2naiikqed(2,4-dinitrophenyl) mus musculus 6.08 0.7364999999999999 10 PMID:12590613 -3.4.24.61 beta-endorphin mus musculus 5.03 4.165 2 PMID:12590613 -3.4.24.61 calcitonin mus musculus 2.94 2.375 2 PMID:12590613 -3.4.24.61 somatostatin-14 mus musculus 6.08 0.95 3 PMID:12590613 -3.4.24.63 abz-mgwmdeidk(dnp)sg-oh homo sapiens 71.7 71.7 1 PMID:26256061 -3.4.24.63 abz-vkmdae-eddnp homo sapiens 13.5 13.5 1 PMID:22879596 -3.4.24.63 abz-vnldae-eddnp homo sapiens 20.9 20.9 1 PMID:22879596 -3.4.24.63 abz-yvaeapk(dnp)g-oh homo sapiens 35.0 35.0 1 PMID:26256061 -3.4.24.63 actin rattus norvegicus 0.625 0.625 1 PMID:21795642 -3.4.24.63 bradykinin rattus norvegicus 11.0 11.0 1 PMID:12437103 -3.4.24.63 cholecystokinin 8 sulfate mus musculus 13.9 13.9 1 PMID:12888571 -3.4.24.63 gastri-releasing peptide-(14-27) mus musculus 12.6 12.6 1 PMID:11278902 -3.4.24.63 gastrin mus musculus 12.4 12.4 1 PMID:11278902 -3.4.24.63 gastrin 17 mus musculus 11.1 11.05 2 PMID:12888571 -3.4.24.63 glucagon mus musculus 26.8 21.35 2 PMID:11278902 -3.4.24.63 kkgyvadap-4-nitroanilide homo sapiens 20.0 20.0 2 PMID:30098994 -3.4.24.63 kkgyvadap-7-amido-4-methylcoumarin homo sapiens 4.0 4.0 2 PMID:30098994 -3.4.24.63 orcokinin mus musculus 23.4 23.4 1 PMID:11278902 -3.4.24.63 scck8nh2 mus musculus 13.9 13.9 1 PMID:11278902 -3.4.24.63 villin rattus norvegicus 150.0 150.0 1 PMID:21795642 -3.4.24.64 abz-fqtkvaak(dnp)-nh2 homo sapiens 0.057 0.057 1 PMID:26082885 -3.4.24.64 abz-frsgqplqnkvqlq-ed(dnp) homo sapiens 0.122 0.122 1 PMID:26082885 -3.4.24.64 abz-fsskttvk(dnp)-nh2 homo sapiens 0.036 0.036 1 PMID:26082885 -3.4.24.64 abz-ikqssllk(dnp)-nh2 homo sapiens 0.055 0.055 1 PMID:26082885 -3.4.24.64 abz-mtaalktk(dnp)-nh2 homo sapiens 0.19 0.19 1 PMID:26082885 -3.4.24.64 abz-nlmkkstk(dnp)-nh2 homo sapiens 0.028 0.028 1 PMID:26082885 -3.4.24.64 abz-qplankvq-ed(dnp) homo sapiens 0.057 0.057 1 PMID:26082885 -3.4.24.64 abz-qplqakvq-ed(dnp) homo sapiens 0.0943 0.0943 1 PMID:26082885 -3.4.24.64 abz-qplqnkvq-ed(dnp) homo sapiens 0.061 0.061 1 PMID:26082885 -3.4.24.64 abz-ttklkaak(dnp)-nh2 homo sapiens 0.07 0.07 1 PMID:26082885 -3.4.24.64 abz-vaaqtktk(dnp)-nh2 homo sapiens 0.05 0.05 1 PMID:26082885 -3.4.24.64 abz-vissrlek(dnp)-nh2 homo sapiens 0.083 0.083 1 PMID:26082885 -3.4.24.64 abz-vrnfrsgqplqnkvq-ed(dnp) homo sapiens 0.223 0.223 1 PMID:26082885 -3.4.24.64 abz-wttggkak(dnp)-nh2 homo sapiens 0.0033 0.0033 1 PMID:26082885 -3.4.24.64 mdh1-21 rattus norvegicus 1.4 1.4 1 PMID:9829990 -3.4.24.65 2-aminobenzoyl-plalwrsq-2-(2,4-dinitrophenyl)aminoethylamide homo sapiens 1.5 1.175 2 PMID:26760307 -3.4.24.65 2-aminobenzoyl-plgleea-2-(2,4-dinitrophenyl)aminoethylamide homo sapiens 0.55 0.42000000000000004 2 PMID:26760307 -3.4.24.65 2-aminobenzoyl-rplaleesq-2-(2,4-dinitrophenyl)aminoethylamide homo sapiens 2.4 1.33 2 PMID:26760307 -3.4.24.65 2-aminobenzoyl-rplalweeq-2-(2,4-dinitrophenyl)aminoethylamide homo sapiens 1.3 0.735 2 PMID:26760307 -3.4.24.65 2-aminobenzoyl-rplalwesq-2-(2,4-dinitrophenyl)aminoethylamide homo sapiens 2.8 1.4549999999999998 2 PMID:26760307 -3.4.24.65 2-aminobenzoyl-rplalwrsq-2-(2,4-dinitrophenyl)aminoethylamide homo sapiens 5.5 2.7665 2 PMID:26760307 -3.4.24.65 2-aminobenzoyl-rplelwrsq-2-(2,4-dinitrophenyl)aminoethylamide homo sapiens 1.4 0.707 2 PMID:26760307 -3.4.24.65 2-aminobenzoyl-rplgleea-2-(2,4-dinitrophenyl)aminoethylamide homo sapiens 3.8 1.9949999999999999 2 PMID:26760307 -3.4.24.65 feln-100 homo sapiens 0.01 0.01 1 PMID:21967233 -3.4.24.65 mca-pro-leu-gly-leu-dpa-ala-arg-nh2 homo sapiens 17.3 17.3 1 PMID:21967233 -3.4.24.69 ac-erdqklselddradalqag-(7-methoxy-4-methylcoumaryl)lys-sq-diaminopropionic acid(2,4-dinitrophenyl)-essaaklkrkywwknlk-nh2 clostridium botulinum 3.81 3.81 1 PMID:19747823 -3.4.24.69 ac-iignlrh(nle)ald(nle)gneidtqnrqidri(nle)ekadsnktridean(pno2-phe)ra(1-pyrenylalanine)k(nle)l-nh2 clostridium botulinum 1.15 1.15 1 PMID:19429547 -3.4.24.69 ac-iignlrhmaldmgneidtqnrqidrimekadsnktridean(pno2-phe)ra(1-pyrenylalanine)k(nle)l-nh2 clostridium botulinum 2.08 2.08 1 PMID:19429547 -3.4.24.69 ac-ksdsnktridean(pno2-phe)ra(1-pyrenylalanine)k(nle)lgsg-nh2 clostridium botulinum 1.01 1.01 1 PMID:19429547 -3.4.24.69 ac-snktridcanqratkml-nh2 clostridium botulinum 23.0 23.0 1 PMID:9755859 -3.4.24.69 ac-snktridean(pno2-phe)ra(1-pyrenylalanine)k(nle)l-nh2 clostridium botulinum 0.79 0.79 1 PMID:19429547 -3.4.24.69 ac-snktrideanqratkml-nh2 clostridium botulinum 47.0 47.0 1 PMID:9755859 -3.4.24.69 ac-snktrideanqrctkml-nh2 clostridium botulinum 31.0 31.0 1 PMID:9755859 -3.4.24.69 ac-snktridecnqratkml clostridium botulinum 4.6 4.6 1 PMID:9755859 -3.4.24.69 snap-25 clostridium botulinum 38.1 2.2169999999999996 6 PMID:10956050;PMID:17189717;PMID:20877571;PMID:23779108 -3.4.24.69 snap25 clostridium botulinum 60.0 12.35 5 PMID:17244603;PMID:18213512 -3.4.24.69 snaptide clostridium botulinum 0.21 0.21 1 PMID:28137423 -3.4.24.69 snaptide 520 clostridium botulinum 0.343 0.343 1 PMID:29030733 -3.4.24.69 snaptide 521 clostridium botulinum 0.052 0.052 1 PMID:29030733 -3.4.24.69 snktrideaaqratkml clostridium botulinum 1.8 1.8 1 PMID:9055204 -3.4.24.69 snktrideanbratkml clostridium botulinum 7.7 7.7 1 PMID:9055204 -3.4.24.69 snktrideannratkml clostridium botulinum 19.0 19.0 1 PMID:9055204 -3.4.24.69 snktrideanqrabkml clostridium botulinum 35.0 35.0 1 PMID:9055204 -3.4.24.69 snktrideanqrataml clostridium botulinum 8.0 8.0 1 PMID:9055204 -3.4.24.69 snktrideanqratk clostridium botulinum 1.0 1.0 1 PMID:9055204 -3.4.24.69 snktrideanqratkal clostridium botulinum 25.0 25.0 1 PMID:9055204 -3.4.24.69 snktrideanqratkm clostridium botulinum 56.0 56.0 1 PMID:9055204 -3.4.24.69 snktrideanqratkml clostridium botulinum 47.0 28.0 2 PMID:9055204 -3.4.24.69 snktrideanqratkxl clostridium botulinum 30.0 30.0 1 PMID:9055204 -3.4.24.69 snktrideanqrbtkml clostridium botulinum 39.0 39.0 1 PMID:9055204 -3.4.24.69 snktridebnqratkml clostridium botulinum 11.0 11.0 1 PMID:9055204 -3.4.24.69 snktridqanqratkml clostridium botulinum 51.0 51.0 1 PMID:9055204 -3.4.24.69 snktrineanqratkml clostridium botulinum 5.0 5.0 1 PMID:9055204 -3.4.24.69 synaptosome-associated protein snap-25 clostridium botulinum 11.1 4.29 3 PMID:14766304;PMID:15938619 -3.4.24.69 vamp-2 clostridium botulinum 594.6 220.8 3 PMID:21029044;PMID:25858313 -3.4.24.69 vamp2 clostridium botulinum 1.0 1.0 1 PMID:19747823 -3.4.24.69 vesicle-associated membrane protein-1 clostridium botulinum 4.52 4.52 1 PMID:29540745 -3.4.24.69 vesicle-associated membrane protein-2 clostridium baratii 35.0 35.0 1 PMID:30071628 -3.4.24.69 vesicle-associated membrane protein-2 clostridium botulinum 938.9 14.865 6 PMID:23963459;PMID:26794648;PMID:29688327;PMID:30071628 -3.4.24.7 [alpha1(ii)769-783] fluorogenic triple-helical peptide-3 homo sapiens 0.08 0.08 1 PMID:12437092 -3.4.24.7 [alpha1(ii)769-783] fluorogenic triple-helical peptide-4 homo sapiens 0.04 0.04 1 PMID:12437092 -3.4.24.7 [alpha1(ii)769-783] single-stranded peptide-3 homo sapiens 0.25 0.25 1 PMID:12437092 -3.4.24.7 acetyl-pro-leu-gly-ile-leu-gly-oc2h5 homo sapiens 4.3 4.3 1 PMID:3002449 -3.4.24.7 acetyl-pro-leu-gly-leu-leu-gly-oc2h5 homo sapiens 5.83 5.83 1 PMID:3002449 -3.4.24.7 acetyl-pro-leu-gly-sch[ch2ch(ch3)2co]-leu-leu-oc2h5 homo sapiens 103.0 103.0 1 PMID:3002449 -3.4.24.7 alpha1(i)772-786 triple-helical peptide homo sapiens 0.11 0.11 1 PMID:12437092 -3.4.24.7 bovine type i collagen bos taurus 0.00147 0.00147 1 PMID:1311165 -3.4.24.7 collagen i alpha-1 chain homo sapiens 10.41 0.655 8 PMID:20549272 -3.4.24.7 collagen i alpha-2 chain homo sapiens 58.61 2.44 8 PMID:20549272 -3.4.24.7 fthp-3 homo sapiens 0.087 0.08349999999999999 2 PMID:11341845 -3.4.24.7 gly-pro-gln-gly-ile-ala-gly-gln-gln homo sapiens 0.2 0.2 1 PMID:12437092 -3.4.24.7 gly-pro-gln-gly-ile-ala-gly-gln-gln-arg-gly-val-val-gly-leu-hyp-nh2 homo sapiens 0.51 0.51 1 PMID:12437092 -3.4.24.7 gplgiagq homo sapiens 0.333 0.333 1 PMID:3032960 -3.4.24.7 gpqgiaga homo sapiens 0.217 0.217 1 PMID:3032960 -3.4.24.7 gpqgiagq homo sapiens 0.203 0.203 1 PMID:3032960 -3.4.24.7 gpqgiagt homo sapiens 0.263 0.263 1 PMID:3032960 -3.4.24.7 gpqglagq homo sapiens 0.27 0.27 1 PMID:3032960 -3.4.24.7 gprgiagq homo sapiens 0.0717 0.0717 1 PMID:3032960 -3.4.24.7 gpvgiagq homo sapiens 0.15 0.15 1 PMID:3032960 -3.4.24.7 human type i collagen bos taurus 0.0035 0.0035 1 PMID:1311165 -3.4.24.7 human type i collagen homo sapiens 0.0148 0.0148 1 PMID:1311165 -3.4.24.7 human type i collagen rattus norvegicus 0.00375 0.00375 1 PMID:1311165 -3.4.24.7 human type ii collagen homo sapiens 0.000267 0.000267 1 PMID:1311165 -3.4.24.7 human type ii collagen rattus norvegicus 0.00392 0.0021514999999999998 2 PMID:1311165 -3.4.24.7 human type iii collagen bos taurus 0.0958 0.0958 1 PMID:1311165 -3.4.24.7 human type iii collagen homo sapiens 0.153 0.0793 2 PMID:1311165 -3.4.24.7 type i collagen homo sapiens 0.00278 0.00278 1 PMID:3032960 -3.4.24.7 type iii collagen homo sapiens 0.077 0.077 1 PMID:19398000 -3.4.24.70 abz-gaspfrq-eddnp escherichia coli 0.5 0.5 1 PMID:20513640 -3.4.24.70 abz-gdspfrq-eddnp escherichia coli 0.2 0.2 1 PMID:20513640 -3.4.24.70 abz-gespfrq-eddnp escherichia coli 0.08 0.08 1 PMID:20513640 -3.4.24.70 abz-gfspfrq-eddnp escherichia coli 1.1 1.1 1 PMID:20513640 -3.4.24.70 abz-ggspfrq-eddnp escherichia coli 0.2 0.2 1 PMID:20513640 -3.4.24.70 abz-ghspfrq-eddnp escherichia coli 0.74 0.74 1 PMID:20513640 -3.4.24.70 abz-gkspfrq-eddnp escherichia coli 0.4 0.4 1 PMID:20513640 -3.4.24.70 abz-glspfrq-eddnp escherichia coli 1.5 1.5 1 PMID:20513640 -3.4.24.70 abz-gnspfrq-eddnp escherichia coli 0.5 0.5 1 PMID:20513640 -3.4.24.70 abz-gpspfrq-eddnp escherichia coli 0.1 0.1 1 PMID:20513640 -3.4.24.70 abz-gqspfrq-eddnp escherichia coli 0.6 0.6 1 PMID:20513640 -3.4.24.70 abz-grspfrq-eddnp escherichia coli 2.4 2.4 1 PMID:20513640 -3.4.24.70 abz-gsspfrq-eddnp escherichia coli 0.3 0.3 1 PMID:20513640 -3.4.24.70 abz-gyspfrq-eddnp escherichia coli 1.5 1.5 1 PMID:20513640 -3.4.24.71 big endothelin-1 homo sapiens 0.112 0.097 3 PMID:9808768 -3.4.24.72 arg-pro-pro-gly-phe-ser-pro-phe-arg agkistrodon contortrix 6.03 6.03 1 PMID:15578961;PMID:15882884 -3.4.24.72 his-thr-glu-ala-leu-val-thr-ser agkistrodon contortrix 5.0 5.0 1 PMID:15578961;PMID:15882884 -3.4.24.72 his-thr-glu-arg-leu-val-thr-ser agkistrodon contortrix 1.97 1.97 1 PMID:15578961;PMID:15882884 -3.4.24.72 his-thr-glu-asn-leu-val-thr-ser agkistrodon contortrix 65.7 65.7 1 PMID:15578961;PMID:15882884 -3.4.24.72 his-thr-glu-glu-leu-val-thr-ser agkistrodon contortrix 0.46 0.46 1 PMID:15578961;PMID:15882884 -3.4.24.72 his-thr-glu-his-leu-val-thr-ser agkistrodon contortrix 5.19 5.19 1 PMID:15578961;PMID:15882884 -3.4.24.72 his-thr-glu-leu-leu-val-thr-ser agkistrodon contortrix 0.16 0.16 1 PMID:15578961;PMID:15882884 -3.4.24.72 his-thr-glu-lys-leu-val-thr-ser agkistrodon contortrix 2.23 2.23 1 PMID:15578961;PMID:15882884 -3.4.24.72 his-thr-glu-lys-phe-val-thr-ser agkistrodon contortrix 0.2 0.2 1 PMID:15578961;PMID:15882884 -3.4.24.72 his-thr-glu-phe-leu-val-thr-ser agkistrodon contortrix 0.45 0.45 1 PMID:15578961;PMID:15882884 -3.4.24.72 his-thr-glu-pro-leu-val-thr-ser agkistrodon contortrix 1.59 1.59 1 PMID:15578961;PMID:15882884 -3.4.24.72 his-thr-glu-ser-leu-val-thr-ser agkistrodon contortrix 3.98 3.98 1 PMID:15578961;PMID:15882884 -3.4.24.72 leu-val-glu-ala-leu-tyr-leu-val agkistrodon contortrix 0.09 0.09 1 PMID:15578961;PMID:15882884 -3.4.24.72 low molecular weight kininogen agkistrodon contortrix 0.0086 0.0086 1 PMID:15578961;PMID:15882884 -3.4.24.73 abz-lvealyq-eddnp bothrops jararaca 0.14 0.093 3 PMID:15313443 -3.4.24.75 pentaglycine staphylococcus simulans 0.05 0.05 1 PMID:33348544 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-ala-asp-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-ala-ile-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-ala-lys-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-ala-pro-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-ala-tyr-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-arg-asp-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-arg-ile-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-arg-lys-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-arg-pro-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-arg-tyr-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-glu-asp-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-glu-ile-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-glu-lys-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-glu-pro-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-glu-tyr-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-phe-asp-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-phe-ile-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-phe-lys-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-phe-pro-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-phe-tyr-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-val-asp-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-val-ile-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-val-lys-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-val-pro-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.77 n-[2-(n-methylamino)benzoyl]-2,3-diaminopropionic acid-gly-val-tyr-phe-ala-phe-pro-lys(2,4-dinitrophenyl)-d-arg-d-arg streptomyces septatus 5.0 5.0 1 PMID:15639229 -3.4.24.79 igfbp-4 homo sapiens 0.89 0.765 2 PMID:17249697 -3.4.24.79 igfbp-5 homo sapiens 0.75 0.47 3 PMID:17249697 -3.4.24.80 (gly-pro-hyp)5-gly-pro-lys(mca)-gly-pro-gln-gly-cys(mob)-arg-gly-gln-lys(dnp)-gly-val-arg-(gly-pro-hyp)5-nh2 homo sapiens 0.84 0.49 2 PMID:30480376 -3.4.24.80 collagen i alpha-1 chain homo sapiens 1.1 0.575 4 PMID:20549272 -3.4.24.80 collagen i alpha-2 chain homo sapiens 255.6 7.84 4 PMID:20549272 -3.4.24.80 collagen type i alpha-1 chain homo sapiens 10.41 2.4949999999999997 4 PMID:20549272 -3.4.24.80 collagen type i alpha-2 chain homo sapiens 58.61 2.052 4 PMID:20549272 -3.4.24.80 methoxycoumarin-4-acetyl-lys-pro-leu-gly-leu-lys(2,4-dinitrophenyl)-ala-arg-nh2 homo sapiens 6.8 2.75 4 PMID:26636948 -3.4.24.80 mocacplgla2pr-dinitrophenol-a-rnh2 homo sapiens 0.055 0.0375 2 PMID:12004057 -3.4.24.80 type i collagen chain alpha-1 homo sapiens 1.05 1.05 1 PMID:17379243 -3.4.24.80 type i collagen chain alpha-2 homo sapiens 0.99 0.99 1 PMID:17379243 -3.4.24.81 glu(edans)-pro-leu-ala-gln-ala-val-arg-ser-ser(glycosyl)-ser-lys(dabcyl) homo sapiens 0.06 0.06 1 PMID:22927435 -3.4.24.81 glu(edans)-pro-leu-ala-gln-ala-val-arg-ser-ser-ser-lys(dabcyl) homo sapiens 0.28 0.28 1 PMID:22927435 -3.4.24.82 [c6-(gly-pro-hyp)5-gly-thr-lys(7-amido-4-methylcoumarin)-gly-glu-leu-glu-gly-arg-gly-thr-lys(2,4-dinitrophenyl)-gly-ile-ser-(gly-pro-hyp)5-nh2]3 homo sapiens 0.181 0.0965 2 PMID:17095512 -3.4.24.82 aggrecan homo sapiens 1.49 1.49 1 PMID:17470431 -3.4.24.82 c6-(gly-pro-hyp-pro-hyp-gly)2-gly-pro-hyp-gly-thr-lys(mca)-gly-glu-leu-glu-gly-arg-gly-thr-lys(dnp)-gly-ile-ser-(gly-pro-hyp-pro-hyp-gly)2-gly-pro-hyp-nh2 homo sapiens 0.433 0.2525 2 PMID:17095512 -3.4.24.82 chondroitin 4-sulfate homo sapiens 1.16 1.16 1 PMID:17470431 -3.4.24.83 acetyl-gly-tyr-beta-ala-arg-arg-arg-arg-arg-arg-arg-arg-val-leu-arg-4-nitroanilide bacillus anthracis 26.6 18.6 2 PMID:29407865 -3.4.24.83 acetyl-gly-tyr-beta-ala-arg-arg-arg-arg-arg-arg-arg-arg-val-leu-arg-7-amido-4-methylcoumarin bacillus anthracis 6.1 5.0 2 PMID:29407865 -3.4.24.83 acetyl-gybetaarrrrrrrrvlr-4-nitroanilide bacillus anthracis 21.2 21.2 1 PMID:25042732 -3.4.24.83 fluorescein-qrrkkvypypme bacillus anthracis 0.52 0.52 1 PMID:19359249 -3.4.24.86 (edans)-elaqavrsssrk-(dabcyl) homo sapiens 0.2 0.125 2 PMID:23779109 -3.4.24.86 (edans)-eplaqavrsssk-(dabcyl) homo sapiens 0.14 0.085 4 PMID:23779109 -3.4.24.86 abz-asn-tyr-met-ala-leu-arg-arg-dap(dnp)-nh2 homo sapiens 0.203 0.203 1 PMID:37783443 -3.4.24.86 abz-asn-tyr-met-ala-leu-arg-arg-lys(dnp)-nh2 homo sapiens 0.577 0.577 1 PMID:37783443 -3.4.24.86 abz-asn-tyr-met-ala-leu-arg-arg-tyr(3-no2)-nh2 homo sapiens 0.0962 0.0962 1 PMID:37783443 -3.4.24.86 glu(edans)-pro-leu-ala-gln-ala-val-arg-ser-ser(4o-(beta-d-gal-(1->3)-alpha-d-galnac))-ser-lys(dabcyl) homo sapiens 0.25 0.25 1 PMID:22927435 -3.4.24.86 glu(edans)-pro-leu-ala-gln-ala-val-arg-ser-ser-ser-lys(dabcyl) homo sapiens 0.14 0.14 1 PMID:22927435 -3.4.24.86 s80-glycosylated (edans)-elaqavrsssrk-(dabcyl) homo sapiens 0.42 0.25 2 PMID:23779109 -3.4.24.86 s80-glycosylated (edans)-eplaqavrsssk-(dabcyl) homo sapiens 0.36 0.235 4 PMID:23779109 -3.4.24.87 dreqapnlvymvtgnpasdeikrlpgdiqvvpigvgpnanvqelerigwpnapiliqdfetlpreapdlvlqra homo sapiens 0.72 0.72 1 PMID:19969076 -3.4.24.87 fret-vwf115 peptide homo sapiens 1.31 1.31 1 PMID:19047683 -3.4.24.87 fretsvwf73 peptide homo sapiens 4.43 4.43 1 PMID:19541819 -3.4.24.87 hrph-a2-b homo sapiens 0.67 0.67 1 PMID:17121983 -3.4.24.87 von willebrand factor 115 homo sapiens 0.52 0.33 2 PMID:16221672;PMID:20647566 -3.4.24.87 vwf115 homo sapiens 0.71 0.35595 2 PMID:19234142;PMID:25512499 -3.4.24.87 vwf115 d1614a mutant homo sapiens 0.008 0.008 1 PMID:19234142 -3.4.24.87 vwf73 peptide homo sapiens 1.32 1.32 1 PMID:20075158 -3.4.24.89 abz-dvvnapvppskdd-conh2 clostridioides difficile 1.26 1.26 1 PMID:31182482 -3.4.24.89 abz-dvvnpavppskdd-conh2 clostridioides difficile 0.87 0.87 1 PMID:31182482 -3.4.24.89 abz-dvvnppvppskdd-conh2 clostridioides difficile 4.3 4.3 1 PMID:31182482 -3.4.24.89 dabcyl-lys-evnppppd-edansglu clostridioides difficile 19.0 19.0 1 * -3.4.24.89 ypsskplppvppvqplppvpklets paenibacillus alvei 8.0 5.0 2 PMID:29794027 -3.4.25.1 abz-val-val-ser-(4-guanidino-phe)-ala-met-gly-tyr(3-no2)-nh2 homo sapiens 8.4 8.4 1 PMID:26314791 -3.4.25.1 abz-val-val-ser-arg-ser-leu-gly-tyr(3-no2)-nh2 homo sapiens 16.5 16.5 1 PMID:26314791 -3.4.25.1 acetyl-arg-hser-thr-arg-7-amido-4-methylcoumarin homo sapiens 2.837 2.837 1 PMID:29806773 -3.4.25.1 acetyl-betaala-met(sulfone)-thr-arg-7-amido-4-methylcoumarin homo sapiens 2.233 2.233 1 PMID:29806773 -3.4.25.1 acetyl-epfd-7-amido-4-carbamoylcoumarin homo sapiens 0.97 0.97 1 PMID:12600991 -3.4.25.1 acetyl-epfd-7-amido-4-carbamoylcoumarin trypanosoma brucei 2.7 2.7 1 PMID:12600991 -3.4.25.1 acetyl-harg-pro-2-fluoro-phe-asp-7-amido-4-methylcoumarin homo sapiens 1.844 1.844 1 PMID:29806773 -3.4.25.1 acetyl-harg-pro-abu-asp-7-amido-4-methylcoumarin homo sapiens 1.343 1.343 1 PMID:29806773 -3.4.25.1 acetyl-hhsl-7-amido-4-carbamoylcoumarin homo sapiens 36.3 36.3 1 PMID:12600991 -3.4.25.1 acetyl-norleucine-arg-norleucine-arg-7-amido-4-carbamoylcoumarin homo sapiens 5.34 4.32 2 PMID:12600991 -3.4.25.1 acetyl-norleucine-arg-norleucine-arg-7-amido-4-carbamoylcoumarin trypanosoma brucei 8.15 4.33 2 PMID:12600991 -3.4.25.1 acetyl-ywtq-7-amido-4-carbamoylcoumarin homo sapiens 0.27 0.27 1 PMID:12600991 -3.4.25.1 acetyl-ywtq-7-amido-4-carbamoylcoumarin trypanosoma brucei 4.67 3.985 2 PMID:12600991 -3.4.25.1 benzyloxycarbonyl-arr-7-amido-4-methylcoumarin struthio camelus 2.94 2.94 1 PMID:12437115 -3.4.25.1 benzyloxycarbonyl-ggf-4-aminobenzoate bos taurus 0.2 0.2 1 PMID:10686146 -3.4.25.1 benzyloxycarbonyl-ggl-7-amido-4-methylcoumarin struthio camelus 16.9 16.9 1 PMID:12437115 -3.4.25.1 benzyloxycarbonyl-ggr-7-amido-4-methylcoumarin struthio camelus 2.1 2.1 1 PMID:12437115 -3.4.25.1 benzyloxycarbonyl-gpafg-4-aminobenzoate bos taurus 18.8 2.9699999999999998 4 PMID:10686146 -3.4.25.1 benzyloxycarbonyl-gpalg-4-aminobenzoate bos taurus 12.9 3.75 5 PMID:10686146 -3.4.25.1 benzyloxycarbonyl-lle-2-naphthylamide struthio camelus 0.332 0.332 1 PMID:12437115 -3.4.25.1 benzyloxycarbonyl-rr-7-amido-4-methylcoumarin struthio camelus 0.143 0.143 1 PMID:12437115 -3.4.25.1 succinyl-llvy-7-amido-4-methylcoumarin struthio camelus 6.08 6.08 1 PMID:12437115 -3.4.25.2 arc-myl-st11 escherichia coli 0.11 0.11 1 PMID:15696175 -3.4.25.2 arc-myl-st11 plus escherichia coli 0.077 0.077 1 PMID:15696175 -3.4.25.2 arc1-53-st11-titin-ssra escherichia coli 0.11 0.11 1 PMID:15696175 -3.4.25.2 sula haemophilus influenzae 0.05 0.05 1 PMID:15037245 -3.4.25.2 sula mutant f10a haemophilus influenzae 0.063 0.063 1 PMID:15037245 -3.4.25.2 sula mutant i37v haemophilus influenzae 0.068 0.068 1 PMID:15037245 -3.4.25.2 sula mutant p8l haemophilus influenzae 0.033 0.033 1 PMID:15037245 -3.4.26.2 7-amido-4-methylcoumarin-klapsk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 1.6 1.6 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klassk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 6.0 6.0 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-kldpsk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 0.6 0.6 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-kldssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 17.0 17.0 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klepsk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 0.4 0.4 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klessk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 0.2 0.2 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klfpsk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 13.0 13.0 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klfssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 200.0 200.0 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klgpsk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 0.4 0.4 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klgssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 3.6 3.6 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klhpsk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 33.0 33.0 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klhssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 145.0 145.0 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klkpsk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 3.5 3.5 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klkssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 8.0 8.0 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-kllssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 7.7 7.7 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klmssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 105.0 105.0 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klnpsk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 6.5 6.5 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klnssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 198.0 198.0 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klpssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 7.7 7.7 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klqpsk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 0.4 0.4 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klqssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 0.8 0.8 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klrpsk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 1.1 1.1 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klrssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 15.0 15.0 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klspsk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 0.03 0.03 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klsssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 0.063 0.063 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klvssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 0.048 0.048 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klypsk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 8.7 8.7 1 PMID:20442413 -3.4.26.2 7-amido-4-methylcoumarin-klyssk-glutaminyl-[n-(2,4-dinitrophenyl)-ethylenediamine] scytalidium lignicola 86.0 86.0 1 PMID:20442413 -3.4.26.2 d-dap(menhbz)-gfkffafpk(dnp)-d-arg-d-arg scytalidium lignicola 11.3 11.3 1 PMID:15907842 -3.4.26.2 d-dap(menhbz)-gfkffalrk(dnp)-d-arg-d-arg scytalidium lignicola 34.8 34.8 1 PMID:15907842 -3.5.1.1 asn escherichia coli 24.0 24.0 1 PMID:11106175 -3.5.1.1 beta-l-asp-l-phe cavia porcellus 1.98 1.98 1 PMID:24669941 -3.5.1.1 beta-l-asp-l-phe homo sapiens 0.8 0.8 1 PMID:24768817 -3.5.1.1 d-asn pectobacterium carotovorum 68.0 68.0 1 PMID:15032742 -3.5.1.1 d-asparagine thermococcus gammatolerans 3378.0 3378.0 1 * -3.5.1.1 d-glutamine thermococcus gammatolerans 1362.0 1362.0 1 * -3.5.1.1 l-asn pectobacterium carotovorum 1600.0 1600.0 1 PMID:15032742 -3.5.1.1 l-asparagine bacillus australimaris 74.6 74.6 1 PMID:35718140 -3.5.1.1 l-asparagine bacillus licheniformis 2680.0 36.8 3 PMID:24905227;PMID:25224912;PMID:38092107 -3.5.1.1 l-asparagine bacillus sp. sl-1 19.9 19.9 1 PMID:35876873 -3.5.1.1 l-asparagine bacillus subtilis 48.5 48.5 1 * -3.5.1.1 l-asparagine cavia porcellus 38.6 21.275000000000002 2 PMID:24669941;PMID:25320094 -3.5.1.1 l-asparagine dickeya chrysanthemi 565.0 282.5064 2 PMID:16984804;PMID:24870616 -3.5.1.1 l-asparagine escherichia coli 72.0 53.9 8 PMID:26142822;PMID:29101342;PMID:34303095;PMID:36310372 -3.5.1.1 l-asparagine helicobacter pylori 19.26 19.26 2 PMID:18983825;PMID:25664771 -3.5.1.1 l-asparagine homo sapiens 3.19 3.19 1 PMID:24768817 -3.5.1.1 l-asparagine mycobacterium gordonae 197.75 197.75 1 PMID:34829099 -3.5.1.1 l-asparagine mycobacterium tuberculosis 1732.5 869.4 3 PMID:33412160 -3.5.1.1 l-asparagine pectobacterium carotovorum 160.0 160.0 3 PMID:27542748 -3.5.1.1 l-asparagine priestia megaterium 1.62 1.62 1 PMID:31326332 -3.5.1.1 l-asparagine pseudomonas sp. pch199 33.78 33.78 1 PMID:36828987 -3.5.1.1 l-asparagine pyrococcus furiosus 888.6 453.29 2 PMID:22166247 -3.5.1.1 l-asparagine rhizobium etli 770.0 433.0 12 PMID:22450783;PMID:34795296;PMID:38456185 -3.5.1.1 l-asparagine rhizomucor miehei 676.0 676.0 1 PMID:24362429 -3.5.1.1 l-asparagine saccharomyces cerevisiae 523.0 370.0 2 PMID:27824095 -3.5.1.1 l-asparagine staphylococcus sp. 4.65 4.65 1 PMID:24861344 -3.5.1.1 l-asparagine talaromyces pinophilus 286.3 286.3 1 * -3.5.1.1 l-asparagine thermococcus gammatolerans 5721.0 5721.0 1 * -3.5.1.1 l-asparagine thermococcus kodakarensis 694.0 694.0 1 PMID:24442710 -3.5.1.1 l-asparagine vibrio cholerae 4424.0 4424.0 1 PMID:29307802 -3.5.1.1 l-asparagine withania somnifera 178.6 178.6 1 PMID:19200159 -3.5.1.1 l-asparagine wolinella succinogenes 97.8 97.8 1 PMID:28139703 -3.5.1.1 l-asparagine yersinia pseudotuberculosis 0.22 0.22 1 PMID:22226870 -3.5.1.1 l-aspartyl-beta-hydroxamate escherichia coli 29.0 29.0 1 PMID:11106175 -3.5.1.1 l-aspartyl-beta-hydroxamate pectobacterium carotovorum 450.0 450.0 1 PMID:15032742 -3.5.1.1 l-gln dickeya chrysanthemi 0.0043 0.0043 1 PMID:16984804 -3.5.1.1 l-gln escherichia coli 0.33 0.33 1 PMID:11106175 -3.5.1.1 l-gln pectobacterium carotovorum 42.0 42.0 1 PMID:15032742 -3.5.1.1 l-glutamine bacillus licheniformis 7.47 7.47 1 PMID:38092107 -3.5.1.1 l-glutamine escherichia coli 2.2 1.5 3 PMID:26142822;PMID:29101342;PMID:36310372 -3.5.1.1 l-glutamine helicobacter pylori 22.1 22.1 2 PMID:18983825;PMID:25664771 -3.5.1.1 l-glutamine pectobacterium carotovorum 7.1 6.0 3 PMID:27542748 -3.5.1.1 l-glutamine thermococcus gammatolerans 2048.0 2048.0 1 * -3.5.1.1 l-glutamine wolinella succinogenes 1.58 1.58 1 PMID:28139703 -3.5.1.1 nalpha-acetyl-asn dickeya chrysanthemi 0.0108 0.0108 1 PMID:16984804 -3.5.1.1 nalpha-acetyl-l-asparagine pectobacterium carotovorum 4.1 4.1 1 PMID:27542748 -3.5.1.1 succinamic acid dickeya chrysanthemi 0.0239 0.0239 1 PMID:16984804 -3.5.1.1 succinamic acid pectobacterium carotovorum 4.1 4.1 1 PMID:27542748 -3.5.1.103 1-(2-acetamido-2-deoxy-alpha-d-glucopyranosyl)-1d-myo-inositol mycobacterium tuberculosis 0.49 0.365 2 PMID:16630724;PMID:20304659 -3.5.1.103 n-acetyl-d-glucosamine mycobacterium tuberculosis 0.77 0.77 1 PMID:26024468 -3.5.1.103 n-acetyl-d-glucosamine mycolicibacterium smegmatis 2.1 0.38 7 PMID:21507949;PMID:22315231 -3.5.1.103 n-deacetyl-n-formylmycothiol-monobromobimane conjugate mycobacterium tuberculosis 0.49 0.49 1 PMID:16630724 -3.5.1.103 phenyl-2-acetamido-2-deoxy-1-thio-alpha-d-glucopyranoside mycobacterium tuberculosis 0.12 0.12 1 PMID:20304659 -3.5.1.104 (glcnac)5 bacillus cereus 3000.0 3000.0 1 PMID:29983281 -3.5.1.104 4-nitrophenyl acetate streptococcus pneumoniae 0.46 0.46 1 PMID:21501597 -3.5.1.104 4-yethylumbelliferyl acetate streptococcus pneumoniae 1.64 0.96 2 PMID:21501597 -3.5.1.104 glcnac-beta-1,4-glcnac-beta-1,4-glcnac streptococcus pneumoniae 0.55 0.55 1 PMID:16221761 -3.5.1.104 glcnac-beta-1,4-glcnac-beta-1,4-glcnac-beta-1,4-glcnac bacillus subtilis 0.93 0.585 2 PMID:22277649;PMID:31690626 -3.5.1.104 peptidoglycan-n-acetyl-d-glucosamine bacillus subtilis 0.32 0.32 1 PMID:22277649 -3.5.1.104 peptidoglycan-n-acetyl-d-glucosamine mycobacterium tuberculosis 0.099 0.099 1 PMID:24975018 -3.5.1.105 glcnac-beta-(1,4)-glcnac vibrio parahaemolyticus 29.5 29.5 1 PMID:25479092 -3.5.1.105 n,n'-diacetylchitobiose shewanella baltica 17.0 17.0 1 PMID:27832730 -3.5.1.107 maleamate bordetella bronchiseptica 11.7 11.7 1 PMID:22214383 -3.5.1.108 udp-3-((r)-3-hydroxytetradecanoyl)-n-acetyl-alpha-d-glucosamine escherichia coli 1.5 1.5 1 PMID:20136146 -3.5.1.108 udp-3-o-((r)-3-hydroxymyristoyl)-n-acetylglucosamine escherichia coli 3.3 0.975 6 PMID:10026271;PMID:15705580;PMID:17176046;PMID:20019290 -3.5.1.108 udp-3-o-(n-hexyl-propionamide)-n-acetylglucosamine escherichia coli 0.36 0.36 1 PMID:11237337 -3.5.1.11 (+)-methyl mandelate achromobacter xylosoxidans 12.68 12.68 1 PMID:33549660 -3.5.1.11 (r) -2-(4-hydroxyphenyl)glycine amide escherichia coli 1.2 1.2 1 * -3.5.1.11 (s)-n-acetylphenylglycine escherichia coli 6.08 3.545 2 * -3.5.1.11 2-benzoxazolon-3-yl-acetic acid methyl ester escherichia coli 0.1 0.1 1 * -3.5.1.11 2-nitro-5-(phenoxyacetamido)-benzoic acid achromobacter xylosoxidans 38.66 38.66 1 PMID:33549660 -3.5.1.11 2-nitro-5-[(phenyl-acetyl)amino]benzoic acid escherichia coli 15.0 15.0 1 PMID:19932137 -3.5.1.11 2-nitro-5-[(phenylacetyl)amino]-benzoic acid escherichia coli 18.0 18.0 1 * -3.5.1.11 2-nitro-5-[(phenylacetyl)amino]-benzoic acid providencia rettgeri 145.3 17.6 3 PMID:31381925 -3.5.1.11 2-nitro-5-phenoxyacetamide benzoic acid streptomyces mobaraensis 106.4 106.4 1 PMID:17289203 -3.5.1.11 2-phenyl-n-(4-sulfamoylphenyl)acetamide alcaligenes faecalis 40.03 40.03 1 * -3.5.1.11 2-phenylacetamidobenzoic acid escherichia coli 2.3 2.3 1 PMID:15153118 -3.5.1.11 3-phenylacetamidobenzoic acid escherichia coli 2.5 2.5 1 PMID:15153118 -3.5.1.11 4-hydroxyphenylacetamide escherichia coli 47.0 47.0 1 * -3.5.1.11 4-hydroxyphenylacetamide uncultured gammaproteobacteria bacterium 29.0 29.0 1 * -3.5.1.11 4-nitrophenyl acetate escherichia coli 170.0 170.0 1 PMID:7011386 -3.5.1.11 4-phenylacetamidobenzoic acid escherichia coli 3.0 3.0 1 PMID:15153118 -3.5.1.11 5-nitro-3-[(phenylacetyl)amino]benzoic acid escherichia coli 1.2 1.0 3 * -3.5.1.11 6-aminopenicillanic acid achromobacter sp. 4.81 4.81 1 PMID:37084587 -3.5.1.11 6-nitro-3-(phenylacetamido)-benzoic acid uncultured bacterium 58.3 58.3 1 PMID:24338159 -3.5.1.11 6-nitro-3-[(phenylacetyl)amino]benzoic acid achromobacter xylosoxidans 68.8 68.8 1 PMID:15128530 -3.5.1.11 6-nitro-3-[(phenylacetyl)amino]benzoic acid escherichia coli 27.0 23.0 4 PMID:15153118;PMID:15627395 -3.5.1.11 6-nitro-3-[(phenylacetyl)amino]benzoic acid uncultured gammaproteobacteria bacterium 24.0 24.0 1 * -3.5.1.11 6-nitro-3-phenylacetamidobenzoic acid alcaligenes faecalis 82.0 79.5 2 * -3.5.1.11 6-nitro-3-phenylacetamidobenzoic acid escherichia coli 20.0 20.0 1 * -3.5.1.11 7-phenylacetamidoacetoxycephalosporanic acid escherichia coli 50.0 50.0 1 PMID:7011386 -3.5.1.11 amoxicillin escherichia coli 17.0 17.0 1 * -3.5.1.11 amoxicillin providencia rettgeri 142.3 16.9 3 PMID:31381925 -3.5.1.11 amoxicillin uncultured gammaproteobacteria bacterium 15.0 15.0 1 * -3.5.1.11 amoxycillin uncultured bacterium 56.2 56.2 1 PMID:24338159 -3.5.1.11 ampicillin escherichia coli 37.0 25.0 3 PMID:17933411;PMID:7011386 -3.5.1.11 ampicillin uncultured bacterium 49.5 49.5 1 PMID:24338159 -3.5.1.11 ampicillin uncultured gammaproteobacteria bacterium 16.0 16.0 1 * -3.5.1.11 benzylpenicillin alcaligenes faecalis 80.0 80.0 3 PMID:14622260 -3.5.1.11 benzylpenicillin escherichia coli 50.0 49.0 2 PMID:7011386 -3.5.1.11 benzylpenicillin kluyvera cryocrescens 63.0 41.75 4 PMID:15604805 -3.5.1.11 benzylpenicilloic acid escherichia coli 40.0 40.0 1 PMID:7011386 -3.5.1.11 capsaicin streptomyces mobaraensis 9.5 9.5 1 PMID:17289203 -3.5.1.11 carbenicillin uncultured bacterium 63.7 63.7 1 PMID:24338159 -3.5.1.11 cefadroxil escherichia coli 32.0 32.0 1 * -3.5.1.11 cefadroxil uncultured gammaproteobacteria bacterium 13.0 13.0 1 * -3.5.1.11 cefamandole achromobacter xylosoxidans 22.03 22.03 1 PMID:33549660 -3.5.1.11 cephalexin escherichia coli 54.0 41.5 2 PMID:7011386 -3.5.1.11 cephalexin uncultured bacterium 34.2 34.2 1 PMID:24338159 -3.5.1.11 cephalexin uncultured gammaproteobacteria bacterium 20.0 20.0 1 * -3.5.1.11 cephaloridine escherichia coli 33.0 33.0 1 PMID:7011386 -3.5.1.11 cephaloridine uncultured bacterium 66.9 66.9 1 PMID:24338159 -3.5.1.11 cephalothin escherichia coli 25.0 25.0 1 PMID:7011386 -3.5.1.11 cephalothin uncultured bacterium 78.3 78.3 1 PMID:24338159 -3.5.1.11 d-(-)-alpha-aminophenylacetic acid 4-nitroanilide escherichia coli 0.54 0.54 1 PMID:7011386 -3.5.1.11 d-2-nitro-5-[(phenylacetyl)amino]benzoic acid escherichia coli 14.0 14.0 1 * -3.5.1.11 d-2-nitro-5-[(phenylacetyl)amino]benzoic acid uncultured gammaproteobacteria bacterium 12.0 12.0 1 * -3.5.1.11 d-4-hydroxyphenylglycine amide escherichia coli 8.0 8.0 1 * -3.5.1.11 d-4-hydroxyphenylglycine amide uncultured gammaproteobacteria bacterium 16.0 16.0 1 * -3.5.1.11 d-hydroxyphenylglycine methyl ester providencia rettgeri 102.6 11.73 3 PMID:31381925 -3.5.1.11 d-phenylglycine amide escherichia coli 57.0 31.5 2 PMID:17933411 -3.5.1.11 d-phenylglycine amide uncultured gammaproteobacteria bacterium 25.0 25.0 1 * -3.5.1.11 ethyl 2-phenylacetate escherichia coli 170.0 170.0 1 PMID:7011386 -3.5.1.11 ethyl 4-[(phenylacetyl)amino] benzoate alcaligenes faecalis 41.05 41.05 1 * -3.5.1.11 methyl d-(-)-4-hydroxy-phenyl glycinate achromobacter sp. 4.45 4.45 1 PMID:37084587 -3.5.1.11 n,2-diphenylacetamide alcaligenes faecalis 49.17 49.17 1 * -3.5.1.11 n-(4-acetylphenyl)-2-phenylacetamide alcaligenes faecalis 35.94 35.94 1 * -3.5.1.11 n-(4-bromophenyl)-2-phenylacetamide alcaligenes faecalis 43.07 43.07 1 * -3.5.1.11 n-(4-cyanophenyl)-2-phenylacetamide alcaligenes faecalis 33.84 33.84 1 * -3.5.1.11 n-(4-methoxyphenyl)-2-phenylacetamide alcaligenes faecalis 33.81 33.81 1 * -3.5.1.11 n-(4-methylphenyl)-2-phenylacetamide alcaligenes faecalis 37.93 37.93 1 * -3.5.1.11 n-(4-nitrophenyl)-2-phenylacetamide alcaligenes faecalis 15.14 15.14 1 * -3.5.1.11 n-(5-nitro-2-pyridyl)-phenylacetamide escherichia coli 7.8 7.8 1 PMID:15153118 -3.5.1.11 n-[4-(methylsulfonyl)phenyl]-2-phenylacetamide alcaligenes faecalis 29.49 29.49 1 * -3.5.1.11 n-phenylacetyl-glu escherichia coli 12000.0 12000.0 1 * -3.5.1.11 n2-phenylacetyl-2'-deoxyguanosine escherichia coli 18.0 18.0 1 * -3.5.1.11 n6-phenylacetyl-2'-deoxyadenosine escherichia coli 2.0 2.0 1 * -3.5.1.11 penicillin dihydrof actinoplanes utahensis 4.2 4.2 1 PMID:17586674 -3.5.1.11 penicillin dihydrof streptomyces lavendulae subsp. lavendulae 14.75 14.75 1 PMID:25501472 -3.5.1.11 penicillin f actinoplanes utahensis 1.9 1.9 1 PMID:17586674 -3.5.1.11 penicillin f streptomyces lavendulae subsp. lavendulae 3.33 3.33 1 PMID:25501472 -3.5.1.11 penicillin g achromobacter xylosoxidans 72.7 37.4 2 PMID:15128530 -3.5.1.11 penicillin g actinoplanes utahensis 2.2 2.2 1 PMID:17586674 -3.5.1.11 penicillin g escherichia coli 50.0 50.0 3 PMID:15153118 -3.5.1.11 penicillin g kluyvera cryocrescens 63.0 63.0 1 * -3.5.1.11 penicillin g streptomyces lavendulae subsp. lavendulae 10.95 10.95 1 PMID:25501472 -3.5.1.11 penicillin g streptomyces mobaraensis 12.0 12.0 1 PMID:17289203 -3.5.1.11 penicillin g thermus thermophilus 1.56 1.56 1 PMID:23263966 -3.5.1.11 penicillin g uncultured bacterium 64.2 64.2 1 PMID:24338159 -3.5.1.11 penicillin g uncultured gammaproteobacteria bacterium 25.0 25.0 1 * -3.5.1.11 penicillin k actinoplanes utahensis 33.3 33.3 1 PMID:17586674 -3.5.1.11 penicillin k streptomyces lavendulae subsp. lavendulae 35.58 35.58 1 PMID:25501472 -3.5.1.11 penicillin k thermus thermophilus 5.6 5.6 1 PMID:23263966 -3.5.1.11 penicillin v actinoplanes utahensis 70.3 70.3 1 PMID:17586674 -3.5.1.11 penicillin v lysinibacillus sphaericus 6.38 6.38 1 PMID:30243389 -3.5.1.11 penicillin v streptomyces lavendulae subsp. lavendulae 77.92 77.92 1 PMID:25501472 -3.5.1.11 penicillin v streptomyces mobaraensis 270.8 270.8 1 PMID:17289203 -3.5.1.11 penicillin v uncultured bacterium 48.4 48.4 1 PMID:24338159 -3.5.1.11 phenylacetamide escherichia coli 50.0 48.0 2 PMID:15153118 -3.5.1.11 phenylacetamide uncultured gammaproteobacteria bacterium 23.0 23.0 1 * -3.5.1.11 phenylacetate 4-nitroanilide escherichia coli 55.0 37.5 2 PMID:15153118;PMID:7011386 -3.5.1.11 phenylacetyl-2-naphthylamide escherichia coli 1.9 1.9 1 PMID:15153118 -3.5.1.11 phenylacetyl-7-amido-4-methylcoumarin escherichia coli 3.2 3.2 1 PMID:15153118 -3.5.1.11 phenylacetyl-gly escherichia coli 47.0 47.0 1 * -3.5.1.11 phenylacetylaspartame escherichia coli 35.0 35.0 1 * -3.5.1.110 (z)-3-ureidoacrylate escherichia coli 0.86 0.86 1 PMID:36599150 -3.5.1.111 2-oxoglutaramate paenarthrobacter nicotinovorans 194.0 194.0 1 PMID:21288482 -3.5.1.114 4-hydroxy-2-nonenal mercapturate mus musculus 1.67 0.97 2 PMID:22819785 -3.5.1.114 acrolein mercapturate mus musculus 3.03 1.7149999999999999 2 PMID:22819785 -3.5.1.114 n-acetyl-l-tyrosine mus musculus 2.28 1.2799999999999998 2 PMID:22819785 -3.5.1.114 n-acetyl-s-(1,2-dichlorovinyl)-l-cysteine mus musculus 1.09 0.6100000000000001 2 PMID:22819785 -3.5.1.114 n-acetyl-s-[(2e,6e)-farnesyl]-l-cysteine homo sapiens 2.0 2.0 1 PMID:29290764 -3.5.1.114 n-acetyl-s-geranylgeranyl-l-cysteine homo sapiens 7.2 7.2 1 PMID:29290764 -3.5.1.115 mycothiol bimane corynebacterium glutamicum 0.059 0.059 1 PMID:25514023 -3.5.1.115 mycothiol bimane derivative mycolicibacterium smegmatis 8.0 8.0 1 PMID:10978158 -3.5.1.115 mycothiol disulfide mycobacterium tuberculosis 1.7 1.7 1 PMID:14556638 -3.5.1.115 mycothiol-3-(n-maleimidopropionyl)biocytin mycobacterium tuberculosis 3.0 3.0 1 PMID:14556638 -3.5.1.115 mycothiol-7-(diethylamino)-3-(4'-maleimidylphenyl)-4-methylcoumarin mycobacterium tuberculosis 1.3 1.3 1 PMID:14556638 -3.5.1.115 mycothiol-acetophenone mycobacterium tuberculosis 37.0 37.0 1 PMID:14556638 -3.5.1.115 mycothiol-cerulenin mycobacterium tuberculosis 7.0 7.0 1 PMID:14556638 -3.5.1.115 mycothiol-n-ethylmaleimide mycobacterium tuberculosis 15.0 15.0 1 PMID:14556638 -3.5.1.115 rifs13 mycobacterium tuberculosis 0.82 0.82 1 PMID:14556638 -3.5.1.115 rifs17 mycobacterium tuberculosis 1.04 1.04 1 PMID:14556638 -3.5.1.116 (s)-ureidoglycolate arabidopsis thaliana 761.0 283.0 4 PMID:22493446;PMID:25020232 -3.5.1.116 (s)-ureidoglycolate glycine max 17.0 17.0 1 PMID:23940254 -3.5.1.116 (s)-ureidoglycolate oryza sativa 55.0 55.0 1 PMID:23940254 -3.5.1.117 n-(4-nitrophenyl)-6-aminohexanamide pseudomonas sp. 21.0 21.0 1 PMID:22867796 -3.5.1.117 n-(6-aminohexanoyl)-6-aminohexanoate arthrobacter sp. 19.0 19.0 1 PMID:22867796 -3.5.1.117 n-(6-aminohexanoyl)-6-aminohexanoate pseudomonas sp. 9.2 9.2 1 PMID:22867796 -3.5.1.124 4-nitrophenyl acetate homo sapiens 0.00084 0.00084 1 PMID:34355187 -3.5.1.124 6,8-difluoro-4-methylumbellliferone homo sapiens 0.0127 0.0127 1 PMID:34355187 -3.5.1.124 methylglyoxal homo sapiens 0.02 0.02 1 PMID:31653696 -3.5.1.124 methylglyoxal vibrio cholerae 0.663 0.663 1 PMID:28235098 -3.5.1.124 n-acetyl-l-arginine homo sapiens 310.0 310.0 1 PMID:37688845 -3.5.1.124 n-acetyl-l-cysteine homo sapiens 1400.0 1400.0 1 PMID:37688845 -3.5.1.124 n-acetyl-l-lysine homo sapiens 360.0 360.0 1 PMID:37688845 -3.5.1.124 n6-(1-hydroxy-2-oxopropyl)-n2-acetyl-l-lysine homo sapiens 0.28 0.28 1 PMID:25416785 -3.5.1.124 nomega-(1-hydroxy-2-oxopropyl)-nalpha-acetyl-l-arginine homo sapiens 0.27 0.27 1 PMID:25416785 -3.5.1.124 s-(1-hydroxy-2-oxopropyl)-n-acetyl-l-cysteine homo sapiens 0.42 0.42 1 PMID:25416785 -3.5.1.126 oxamate klebsiella pneumoniae subsp. pneumoniae 5.5 5.5 1 PMID:27303801 -3.5.1.128 n-(4-oxoglutaryl)-l-cysteinylglycine arabidopsis thaliana 4.2 4.2 1 PMID:30692244 -3.5.1.128 n-(4-oxoglutaryl)-l-cysteinylglycine saccharomyces cerevisiae 3.6 3.6 1 PMID:28373563 -3.5.1.129 n5-(cytidine 5'-diphosphoramidyl)-l-glutamine campylobacter jejuni subsp. jejuni serotype o:2 0.55 0.55 1 PMID:29023101 -3.5.1.13 2-chloro-n-(2,6-diethylphenyl) acetamide starkeya sp. 33.1 33.1 1 PMID:30864436 -3.5.1.13 2-chloro-n-(2-methyl-6-ethylphenyl)acetamide starkeya sp. 31.8 31.8 1 PMID:30864436 -3.5.1.13 3',4'-dichloropropionanilide paracoccus sp. m1-1 2.8 2.8 1 PMID:22101784 -3.5.1.13 4-nitroacetanilide nocardia farcinica 19.1 19.1 1 * -3.5.1.13 chlorpropham starkeya sp. 33.7 33.7 1 PMID:30864436 -3.5.1.13 hexanoamide nocardia farcinica 3.5 3.5 1 PMID:18942140 -3.5.1.13 n-(2-nitrophenyl)-trifluoroacetamide bos taurus 237.0 237.0 1 PMID:19292875 -3.5.1.13 n-(2-nitrophenyl)acetamide homo sapiens 0.05 0.05 1 PMID:16504521 -3.5.1.13 n-(2-nitrophenyl)butanamide homo sapiens 0.58 0.58 1 PMID:16504521 -3.5.1.13 n-(2-nitrophenyl)heptanamide homo sapiens 4.98 4.140000000000001 2 PMID:16504521 -3.5.1.13 n-(2-nitrophenyl)hexanamide homo sapiens 3.83 3.83 1 PMID:16504521 -3.5.1.13 n-(2-nitrophenyl)octanamide homo sapiens 5.43 4.365 2 PMID:16504521 -3.5.1.13 n-(2-nitrophenyl)pentanamide homo sapiens 6.0 4.4350000000000005 2 PMID:16504521 -3.5.1.13 n-(2-nitrophenyl)propanamide homo sapiens 0.77 0.77 1 PMID:16504521 -3.5.1.13 n-(2-nitrophenyl)trifluoroacetamide homo sapiens 1672.0 1672.0 1 PMID:16504521 -3.5.1.13 n-(3,4-dichlorophenyl) propanamide paracoccus sp. m1-1 2.8 2.8 1 PMID:22101784 -3.5.1.13 n-(3,4-dichlorophenyl)propanamide paracoccus sp. m1-1 2.8 2.8 1 PMID:22101784 -3.5.1.13 o-nitroacetanilide bos taurus 208.0 208.0 1 PMID:19292875 -3.5.1.13 p-nitroacetanilide nocardia farcinica 5.8 5.8 1 PMID:18942140 -3.5.1.13 propanil starkeya sp. 32.7 32.7 1 PMID:30864436 -3.5.1.13 propham starkeya sp. 33.4 33.4 1 PMID:30864436 -3.5.1.131 1-carboxybiuret pseudomonas sp. adp 15.5 15.5 3 PMID:29523689 -3.5.1.131 1-carboxymalonamide pseudomonas sp. adp 7.0 7.0 1 PMID:29523689 -3.5.1.131 1-nitrobiuret pseudomonas sp. adp 9.4 9.4 1 PMID:29523689 -3.5.1.135 capecitabine escherichia coli 0.016 0.016 1 PMID:31964920 -3.5.1.135 n4-acetyl-2'-deoxycytidine escherichia coli 101.0 101.0 1 PMID:31964920 -3.5.1.135 n4-acetyl-5-fluorocytosine escherichia coli 90.0 90.0 1 PMID:31964920 -3.5.1.135 n4-acetylcytidine escherichia coli 196.0 157.0 3 PMID:31964920 -3.5.1.135 n4-acetylcytosine buttiauxella agrestis 154.0 154.0 1 PMID:36291701 -3.5.1.135 n4-acetylcytosine cronobacter universalis 248.0 248.0 1 PMID:36291701 -3.5.1.135 n4-acetylcytosine escherichia coli 157.0 113.5 2 PMID:31964920;PMID:36291701 -3.5.1.135 n4-acetylcytosine klebsiella pneumoniae 216.0 216.0 1 PMID:36291701 -3.5.1.135 n4-acetylcytosine shewanella loihica 441.0 441.0 1 PMID:36291701 -3.5.1.135 n4-benzoyl-2'-deoxycytidine escherichia coli 0.07 0.07 1 PMID:31964920 -3.5.1.135 n4-benzoylcytidine escherichia coli 1.8 1.8 1 PMID:31964920 -3.5.1.135 n4-hexanoyl-2'-deoxycytidine escherichia coli 24.0 24.0 1 PMID:31964920 -3.5.1.135 n4-isobutyryl-2'-deoxycytidine escherichia coli 75.0 75.0 1 PMID:31964920 -3.5.1.136 n,n'-diacetylchitobiose thermococcus chitonophagus 263.0 161.0 8 PMID:36555375 -3.5.1.136 n-acetyl-beta-d-glucosaminyl-(1->4)-n-acetyl-beta-d-glucosaminyl-(1->4)-n-acetyl-d-glucosamine thermococcus chitonophagus 71.0 71.0 1 PMID:36555375 -3.5.1.136 n-acetyl-d-glucosamine pyrococcus horikoshii 0.21 0.21 1 PMID:33964814 -3.5.1.136 n-acetyl-d-glucosamine thermococcus chitonophagus 226.0 102.0 5 PMID:36555375 -3.5.1.137 1-naphthyl acetate achromobacter sp. wm111 52.7 52.7 1 PMID:19770008 -3.5.1.137 1-naphthyl acetate aspergillus niger 906.0 906.0 1 PMID:14612234 -3.5.1.137 3,5-dimethylphenyl n-methylcarbamate aspergillus niger 1581.0 1581.0 1 PMID:14612234 -3.5.1.137 4-nitrophenyl acetate aspergillus niger 1070.0 1070.0 1 PMID:14612234 -3.5.1.137 aldicarb aspergillus niger 548.0 548.0 1 PMID:14612234 -3.5.1.137 carbaryl achromobacter sp. wm111 1.7 1.7 1 PMID:19770008 -3.5.1.137 carbaryl agrobacterium sp. xwy-2 0.33 0.33 1 PMID:34416635 -3.5.1.137 carbaryl aspergillus niger 1724.0 1724.0 1 PMID:14612234 -3.5.1.137 carbaryl novosphingobium sp. kn65.2 1171.2 1171.2 1 PMID:32835992 -3.5.1.137 carbaryl pseudomonas sp. c5pp 86.0 83.5 2 PMID:29079626 -3.5.1.137 carbaryl pseudomonas sp. c7 84.0 84.0 1 PMID:29079626 -3.5.1.137 carbaryl pseudomonas sp. oxa20 636.4 636.4 1 PMID:32835992 -3.5.1.137 carbaryl pseudomonas sp. xwy-1 2.12 2.12 1 PMID:30216972 -3.5.1.137 carbaryl rhizobium sp. ac100 955.9 955.9 1 PMID:32835992 -3.5.1.137 carbaryl sphingobium sp. cfd-1 100.5 100.5 1 PMID:32835992 -3.5.1.137 carbaryl sphingomonas sp. cds-1 92.5 92.5 1 PMID:32835992 -3.5.1.137 carbofuran aspergillus niger 1282.0 1282.0 1 PMID:14612234 -3.5.1.137 carbofuran novosphingobium sp. kn65.2 19.6 15.530000000000001 2 PMID:27312345;PMID:32835992 -3.5.1.137 carbofuran pseudomonas sp. oxa20 0.6 0.6 1 PMID:32835992 -3.5.1.137 carbofuran rhizobium sp. ac100 0.7 0.7 1 PMID:32835992 -3.5.1.137 carbofuran sphingobium sp. cfd-1 9.5 9.49 2 PMID:31759739;PMID:32835992 -3.5.1.137 carbofuran sphingomonas sp. cds-1 10.2 10.2 1 PMID:32835992 -3.5.1.137 dimethyl umbelliferyl phosphate achromobacter sp. wm111 5.1e-07 5.1e-07 1 PMID:19770008 -3.5.1.137 fenobucarb aspergillus niger 613.0 613.0 1 PMID:14612234 -3.5.1.137 isoprocarb aspergillus niger 670.0 670.0 1 PMID:14612234 -3.5.1.137 methomyl aminobacter aminovorans 345.2 345.2 1 PMID:33097501 -3.5.1.137 metolcarb aspergillus niger 1369.0 1369.0 1 PMID:14612234 -3.5.1.137 oxamyl novosphingobium sp. kn65.2 4.1 4.1 1 PMID:32835992 -3.5.1.137 oxamyl pseudomonas sp. oxa20 5.8 5.8 1 PMID:32835992 -3.5.1.137 oxamyl rhizobium sp. ac100 4.9 4.9 1 PMID:32835992 -3.5.1.137 oxamyl sphingobium sp. cfd-1 0.2 0.2 1 PMID:32835992 -3.5.1.137 oxamyl sphingomonas sp. cds-1 2.7 2.7 1 PMID:32835992 -3.5.1.137 propoxur aspergillus niger 717.0 717.0 1 PMID:14612234 -3.5.1.137 xylylcarb aspergillus niger 1633.0 1633.0 1 PMID:14612234 -3.5.1.14 2-acetylamino-3-((1s,2s)-2-hydroxy-2,2-dimethyl-chroman-4-ylsulfanyl)-propionic acid homo sapiens 150.0 150.0 1 PMID:22349737 -3.5.1.14 2-acetylamino-3-((1s,2s)-2-hydroxy-2,2-dimethyl-chroman-4-ylsulfanyl)-propionic acid sus scrofa 50.0 47.5 2 PMID:22349737 -3.5.1.14 2-acetylamino-3-((1s,2s)-2-hydroxycyclohexylsulfanyl)-propionic acid homo sapiens 120.0 120.0 1 PMID:22349737 -3.5.1.14 2-acetylamino-3-((1s,2s)-2-hydroxycyclohexylsulfanyl)-propionic acid sus scrofa 30.0 28.0 2 PMID:22349737 -3.5.1.14 2-acetylamino-3-((3s,4s)-2-hydroxycyclooctylsulfanyl)-propionic acid sus scrofa 3.0 3.0 1 PMID:22349737 -3.5.1.14 2-acetylamino-3-[(s)-1-((r)-hydroxyphenyl-methyl)-2-oxo-2-phenyl-ethylsulfanyl]-propionic acid homo sapiens 80.0 80.0 1 PMID:22349737 -3.5.1.14 2-acetylamino-3-[(s)-1-((r)-hydroxyphenyl-methyl)-2-oxo-2-phenyl-ethylsulfanyl]-propionic acid sus scrofa 21.0 20.25 2 PMID:22349737 -3.5.1.14 n-2,2-dimethylpropionyl-l-methionine homo sapiens 0.0015 0.0015 1 PMID:18341290 -3.5.1.14 n-2,2-dimethylpropionyl-l-methionine sus scrofa 0.0015 0.0015 1 PMID:18341290 -3.5.1.14 n-acetyl-glycine homo sapiens 31.7 31.7 1 PMID:18222180 -3.5.1.14 n-acetyl-glycine sus scrofa 7.6 7.6 1 PMID:18222180 -3.5.1.14 n-acetyl-l-arginine sus scrofa 8.53 5.25 2 PMID:18222180 -3.5.1.14 n-acetyl-l-cys homo sapiens 30.0 30.0 1 PMID:22349737 -3.5.1.14 n-acetyl-l-cys sus scrofa 18.0 13.5 2 PMID:22349737 -3.5.1.14 n-acetyl-l-cysteine homo sapiens 28.1 28.1 1 PMID:18222180 -3.5.1.14 n-acetyl-l-cysteine sus scrofa 34.7 34.7 1 PMID:18222180 -3.5.1.14 n-acetyl-l-ethionine homo sapiens 12.4 12.4 1 PMID:18222180 -3.5.1.14 n-acetyl-l-ethionine sus scrofa 68.3 68.3 1 PMID:18222180 -3.5.1.14 n-acetyl-l-glutamate homo sapiens 156.0 156.0 2 PMID:18222180;PMID:18341290 -3.5.1.14 n-acetyl-l-glutamate sus scrofa 207.0 207.0 2 PMID:18222180;PMID:18341290 -3.5.1.14 n-acetyl-l-glutamine homo sapiens 30.7 30.7 1 PMID:18222180 -3.5.1.14 n-acetyl-l-glutamine sus scrofa 146.0 146.0 1 PMID:18222180 -3.5.1.14 n-acetyl-l-histidine homo sapiens 1.2 1.2 1 PMID:18222180 -3.5.1.14 n-acetyl-l-histidine sus scrofa 2.77 2.77 1 PMID:18222180 -3.5.1.14 n-acetyl-l-isoleucine sus scrofa 1.28 1.28 1 PMID:18222180 -3.5.1.14 n-acetyl-l-leucine homo sapiens 55.5 55.5 1 PMID:18222180 -3.5.1.14 n-acetyl-l-leucine sus scrofa 160.0 160.0 1 PMID:18222180 -3.5.1.14 n-acetyl-l-met homo sapiens 65.0 65.0 1 PMID:22349737 -3.5.1.14 n-acetyl-l-met sus scrofa 30.0 24.5 2 PMID:22349737 -3.5.1.14 n-acetyl-l-methionine homo sapiens 38.3 38.3 2 PMID:18222180;PMID:18341290 -3.5.1.14 n-acetyl-l-methionine pyrococcus horikoshii 370.0 207.8 2 PMID:11157230;PMID:18248457 -3.5.1.14 n-acetyl-l-methionine sus scrofa 134.0 134.0 2 PMID:18222180;PMID:18341290 -3.5.1.14 n-acetyl-l-norleucine homo sapiens 156.0 156.0 1 PMID:18222180 -3.5.1.14 n-acetyl-l-norleucine sus scrofa 266.0 266.0 1 PMID:18222180 -3.5.1.14 n-acetyl-l-phenylalanine homo sapiens 0.14 0.14 1 PMID:18222180 -3.5.1.14 n-acetyl-l-phenylalanine pyrococcus horikoshii 34.0 34.0 1 PMID:11157230 -3.5.1.14 n-acetyl-l-phenylalanine sus scrofa 0.81 0.81 1 PMID:18222180 -3.5.1.14 n-acetyl-l-phosphinothricin stenotrophomonas geniculata 73.27 73.27 1 PMID:32146938 -3.5.1.14 n-acetyl-l-threonine homo sapiens 2.23 2.23 1 PMID:18222180 -3.5.1.14 n-acetyl-l-threonine sus scrofa 1.21 1.21 1 PMID:18222180 -3.5.1.14 n-acetyl-l-val sus scrofa 2.0 1.85 2 PMID:22349737 -3.5.1.14 n-acetyl-l-valine homo sapiens 14.7 14.7 1 PMID:18222180 -3.5.1.14 n-acetyl-l-valine sus scrofa 11.9 11.9 1 PMID:18222180 -3.5.1.14 n-acetylmethionine rattus norvegicus 2.3 2.3 1 PMID:15938642 -3.5.1.14 n-benzoyl-l-glutamate homo sapiens 0.0101 0.0101 1 PMID:18341290 -3.5.1.14 n-benzoyl-l-glutamate sus scrofa 0.115 0.115 1 PMID:18341290 -3.5.1.14 n-benzoyl-l-methionine homo sapiens 0.158 0.158 1 PMID:18341290 -3.5.1.14 n-benzoyl-l-methionine sus scrofa 1.3 1.3 1 PMID:18341290 -3.5.1.14 n-benzoyl-l-phenylalanine thermococcus litoralis 21300.0 21300.0 1 PMID:21827797 -3.5.1.14 n-benzoyl-l-valine thermococcus litoralis 1760.0 1760.0 1 PMID:21827797 -3.5.1.14 n-butanoyl-l-methionine homo sapiens 139.0 139.0 1 PMID:18341290 -3.5.1.14 n-butanoyl-l-methionine sus scrofa 107.0 107.0 1 PMID:18341290 -3.5.1.14 n-cbz-gly-l-ala deinococcus radiodurans 8.0 8.0 1 PMID:17129628 -3.5.1.14 n-cyclohexanoyl-l-methionine homo sapiens 0.00623 0.00623 1 PMID:18341290 -3.5.1.14 n-cyclohexanoyl-l-methionine sus scrofa 0.145 0.145 1 PMID:18341290 -3.5.1.14 n-cyclopentanoyl-l-methionine homo sapiens 13.3 13.3 1 PMID:18341290 -3.5.1.14 n-cyclopentanoyl-l-methionine sus scrofa 11.2 11.2 1 PMID:18341290 -3.5.1.14 n-formyl-l-methionine homo sapiens 177.0 177.0 1 PMID:18341290 -3.5.1.14 n-formyl-lmethionine sus scrofa 200.0 200.0 1 PMID:18341290 -3.5.1.14 n-formylmethionine rattus norvegicus 7.9 7.9 1 PMID:15938642 -3.5.1.14 n-hexanoyl-l-methionine homo sapiens 16.1 16.1 1 PMID:18341290 -3.5.1.14 n-hexanoyl-l-methionine sus scrofa 4.3 4.3 1 PMID:18341290 -3.5.1.14 n-isobutanoyl-l-methionine homo sapiens 6.08 3.3045 2 PMID:18341290 -3.5.1.14 n-isobutanoyl-l-methionine sus scrofa 89.8 89.8 1 PMID:18341290 -3.5.1.14 n-isopentanoyl-l-methionine homo sapiens 0.105 0.105 1 PMID:18341290 -3.5.1.14 n-isopentanoyl-l-methionine sus scrofa 6.08 3.387 2 PMID:18341290 -3.5.1.14 n-pentanoyl-l-methionine homo sapiens 16.2 16.2 1 PMID:18341290 -3.5.1.14 n-pentanoyl-l-methionine sus scrofa 18.2 18.2 1 PMID:18341290 -3.5.1.14 n-propionyl-l-methionine homo sapiens 25.7 25.7 1 PMID:18341290 -3.5.1.14 n-propionyl-l-methionine sus scrofa 168.0 168.0 1 PMID:18341290 -3.5.1.14 nalpha-acetylmethionine homo sapiens 38.3 38.3 1 PMID:16313167 -3.5.1.15 n-acetyl-l-aspartate homo sapiens 0.083 0.083 1 * -3.5.1.15 n-acetylaspartate homo sapiens 37.5 37.5 1 PMID:18280251 -3.5.1.15 n-acetylaspartic acid homo sapiens 14.22 6.609999999999999 4 PMID:16669630;PMID:17027983 -3.5.1.15 n-chloroacetyl-l-aspartate homo sapiens 0.62 0.62 1 * -3.5.1.15 n-dichloroacetyl-l-aspartate homo sapiens 0.77 0.77 1 * -3.5.1.15 n-formyl-l-aspartate homo sapiens 0.25 0.25 1 * -3.5.1.15 n-trifluoroacetyl-l-aspartate homo sapiens 1.2 1.2 1 * -3.5.1.15 n-trifluoroacetylaspartic acid homo sapiens 116.0 58.6 2 PMID:16669630 -3.5.1.16 n-acetyl-l-ornithine escherichia coli 3800.0 2700.0 2 PMID:22459917 -3.5.1.16 n-alpha-acetyl-l-ornithine escherichia coli 3800.0 1600.0 3 PMID:17333302 -3.5.1.16 n2-acetyl-l-ornithine arabidopsis thaliana 2116.0 2116.0 1 PMID:28064246 -3.5.1.16 n2-acetyl-l-ornithine escherichia coli 3800.0 2700.0 2 PMID:16201833 -3.5.1.18 n-succinyl ll-diaminopimelic acid haemophilus influenzae 140.0 140.0 1 PMID:20138056 -3.5.1.18 n-succinyl-ll-2,6-diaminoheptanedioate haemophilus influenzae 370.0 157.0 4 PMID:24806882;PMID:29698518;PMID:9671518 -3.5.1.18 n-succinyl-ll-2,6-diaminoheptanedioate mycobacterium tuberculosis 4.85 4.85 1 PMID:26976706 -3.5.1.18 n-succinyl-ll-2,6-diaminoheptanedioate vibrio cholerae 80.0 80.0 1 PMID:24806882 -3.5.1.18 n-succinyl-ll-2,6-diaminopimelic acid haemophilus influenzae 140.0 140.0 1 PMID:18712420 -3.5.1.18 n-succinyl-ll-diaminopimelate haemophilus influenzae 140.0 140.0 1 PMID:16421726 -3.5.1.19 5-methyl nicotinamide oceanobacillus iheyensis 5.1 5.1 1 PMID:23451075 -3.5.1.19 5-methylnicotinamide saccharomyces cerevisiae 1.75 1.75 1 PMID:22229411 -3.5.1.19 5-methylnicotinamide uncultured acidobacteriota bacterium 43.7 43.7 1 PMID:28750065 -3.5.1.19 5-methylnicotinamide unidentified 8.2 8.2 1 PMID:28018295 -3.5.1.19 benzamide saccharomyces cerevisiae 0.0088 0.0088 1 PMID:22229411 -3.5.1.19 ethyl nicotinate oceanobacillus iheyensis 0.1 0.1 1 PMID:23451075 -3.5.1.19 ethylnicotinate uncultured acidobacteriota bacterium 3.7 3.7 1 PMID:28750065 -3.5.1.19 ethylnicotinate unidentified 1.1 1.1 1 PMID:28018295 -3.5.1.19 methyl nicotinate oceanobacillus iheyensis 0.32 0.32 1 PMID:23451075 -3.5.1.19 methylnicotinate uncultured acidobacteriota bacterium 54.5 54.5 1 PMID:28750065 -3.5.1.19 methylnicotinate unidentified 7.0 7.0 1 PMID:28018295 -3.5.1.19 nicotinamide acidilobus saccharovorans 76.9 76.9 1 PMID:24512664 -3.5.1.19 nicotinamide arabidopsis thaliana 0.93 0.93 1 PMID:17335512 -3.5.1.19 nicotinamide borreliella burgdorferi 0.003 0.003 1 PMID:20979384 -3.5.1.19 nicotinamide caenorhabditis elegans 3.1 1.69 2 PMID:20979384 -3.5.1.19 nicotinamide mycobacterium tuberculosis 3.1 3.1 1 PMID:20879713 -3.5.1.19 nicotinamide oceanobacillus iheyensis 11.65 11.65 1 PMID:23451075 -3.5.1.19 nicotinamide plasmodium falciparum 0.35 0.32499999999999996 2 PMID:20979384;PMID:36009002 -3.5.1.19 nicotinamide saccharomyces cerevisiae 3.8 2.245 2 PMID:20979384;PMID:22229411 -3.5.1.19 nicotinamide streptococcus pneumoniae 2.1 2.1 1 PMID:20979384 -3.5.1.19 nicotinamide thermus thermophilus 50.0 50.0 1 PMID:28630126 -3.5.1.19 nicotinamide uncultured acidobacteriota bacterium 22.7 22.7 1 PMID:28750065 -3.5.1.19 nicotinamide unidentified 5.0 5.0 1 PMID:28018295 -3.5.1.19 pyrazinamide mycobacterium tuberculosis 3.8 3.8 1 PMID:20879713 -3.5.1.19 pyrazinamide oceanobacillus iheyensis 2.6 2.6 1 PMID:23451075 -3.5.1.19 pyrazinamide saccharomyces cerevisiae 2.56 2.56 1 PMID:22229411 -3.5.1.19 pyrazinamide uncultured acidobacteriota bacterium 18.7 18.7 1 PMID:28750065 -3.5.1.19 pyrazinamide unidentified 7.2 7.2 1 PMID:28018295 -3.5.1.2 2-oxo-glutaramate mus musculus 17.5 17.5 1 PMID:19596042 -3.5.1.2 2-oxo-succinamate mus musculus 1.15 1.01 2 PMID:19596042 -3.5.1.2 5-methoxy-2,5-dioxopentanoic acid mus musculus 134.5 134.5 1 PMID:19596042 -3.5.1.2 gamma-ethyl glutamate escherichia coli 36.0 36.0 1 * -3.5.1.2 gamma-glutamyl hydrazide escherichia coli 14.0 14.0 1 * -3.5.1.2 gamma-glutamyl methoxyamide escherichia coli 296.0 296.0 1 * -3.5.1.2 gamma-glutamyl methylamide escherichia coli 8.0 8.0 1 * -3.5.1.2 gamma-glutamyl-hydroxamate escherichia coli 212.0 212.0 1 * -3.5.1.2 gamma-methyl glutamate escherichia coli 645.0 645.0 1 * -3.5.1.2 gamma-thioethyl glutamate escherichia coli 300.0 300.0 1 * -3.5.1.2 gamma-thiomethyl glutamate escherichia coli 1260.0 1260.0 1 * -3.5.1.2 gln escherichia coli 1270.0 1270.0 1 * -3.5.1.2 glu escherichia coli 5080.0 5080.0 1 * -3.5.1.2 glutaramate mus musculus 8.8 6.45 2 PMID:19596042 -3.5.1.2 gly-gln aspergillus sojae 4790.0 4790.0 1 PMID:23339014 -3.5.1.2 l-asparagine aspergillus sojae 1606.0 1606.0 1 PMID:23339014 -3.5.1.2 l-asparagine helicobacter pylori 19.2 19.2 1 PMID:25664771 -3.5.1.2 l-glutamic acid streptomyces roseolus 2.3 2.3 1 PMID:38889830 -3.5.1.2 l-glutamine aspergillus sojae 6249.0 6249.0 1 PMID:23339014 -3.5.1.2 l-glutamine bacillus cereus 0.222 0.222 1 PMID:23873638 -3.5.1.2 l-glutamine bacillus subtilis 67.7 53.150000000000006 2 PMID:18459799 -3.5.1.2 l-glutamine bizionia argentinensis 320.0 320.0 1 PMID:34085170 -3.5.1.2 l-glutamine escherichia coli 101.0 96.2 2 PMID:18459799 -3.5.1.2 l-glutamine helicobacter pylori 2.1 2.1 1 PMID:25664771 -3.5.1.2 l-glutamine homo sapiens 22.0 10.0 3 PMID:22049910 -3.5.1.2 l-glutamine micrococcus luteus 1400.0 847.5 6 PMID:15290324;PMID:17116585 -3.5.1.2 l-glutamine streptomyces roseolus 293.3 293.3 1 PMID:38889830 -3.5.1.2 succinamate mus musculus 2.8 2.4 2 PMID:19596042 -3.5.1.23 (13e)-n-[(2s,3r,4e)-1,3-dihydroxy-7-[(2-oxo-2h-1-benzopyran-7-yl)oxy]hept-4-en-2-yl]docos-13-enamide homo sapiens 0.004977 0.004977 1 PMID:30926626 -3.5.1.23 (15e)-n-[(2s,3r,4e)-1,3-dihydroxy-7-[(2-oxo-2h-1-benzopyran-7-yl)oxy]hept-4-en-2-yl]tetracos-15-enamide homo sapiens 0.008415 0.008415 1 PMID:30926626 -3.5.1.23 (2r)-n-[(2s,3r,4e)-1,3-dihydroxy-7-[(2-oxo-2h-1-benzopyran-7-yl)oxy]hept-4-en-2-yl]-2-hydroxyicosanamide homo sapiens 0.022954 0.022954 1 PMID:30926626 -3.5.1.23 (2s)-n-[(2s,3r,4e)-1,3-dihydroxy-7-[(2-oxo-2h-1-benzopyran-7-yl)oxy]hept-4-en-2-yl]-2-hydroxyicosanamide homo sapiens 0.007257 0.007257 1 PMID:30926626 -3.5.1.23 (4e,2s,3r)-2-n-(10-pyrenedecanoyl)-1,3,17-trihydroxy-17-(3,5-dinitrobenzoyl)-4-heptadecene pseudomonas aeruginosa 0.1 0.1 1 PMID:11934399 -3.5.1.23 (9e)-n-[(2s,3r,4e)-1,3-dihydroxy-7-[(2-oxo-2h-1-benzopyran-7-yl)oxy]hept-4-en-2-yl]octadec-9-enamide homo sapiens 0.003761 0.003761 1 PMID:30926626 -3.5.1.23 2,4-dideoxy-2-(hexadecanoylamino)-5-o-(2-oxo-2h-1-benzopyran-7-yl)-d-erythro-pentitol homo sapiens 0.00328 0.00328 1 PMID:30926626 -3.5.1.23 2,4-dideoxy-2-[[(13e)-docos-13-enoyl]amino]-5-o-(2-oxo-2h-1-benzopyran-7-yl)-d-erythro-pentitol homo sapiens 0.001397 0.001397 1 PMID:30926626 -3.5.1.23 2,4-dideoxy-2-[[(2r)-2-hydroxyicosanoyl]amino]-5-o-(2-oxo-2h-1-benzopyran-7-yl)-d-erythro-pentitol homo sapiens 0.002655 0.002655 1 PMID:30926626 -3.5.1.23 2,4-dideoxy-2-[[(2s)-2-hydroxyicosanoyl]amino]-5-o-(2-oxo-2h-1-benzopyran-7-yl)-d-erythro-pentitol homo sapiens 0.003075 0.003075 1 PMID:30926626 -3.5.1.23 2,4-dideoxy-2-[[(9e)-octadec-9-enoyl]amino]-5-o-(2-oxo-2h-1-benzopyran-7-yl)-d-erythro-pentitol homo sapiens 0.000423 0.000423 1 PMID:30926626 -3.5.1.23 2,4-dideoxy-5-o-(2-oxo-2h-1-benzopyran-7-yl)-2-[[(15e)-tetracos-15-enoyl]amino]-d-erythro-pentitol homo sapiens 0.001581 0.001581 1 PMID:30926626 -3.5.1.23 c18-ceramide homo sapiens 0.00049 0.00049 1 PMID:28329765 -3.5.1.23 nbd-c12-ceramide homo sapiens 0.7 0.7 1 PMID:26190575 -3.5.1.24 glycochenodeoxycholic acid enterococcus faecalis 2260.0 2260.0 1 * -3.5.1.24 glycochenodeoxycholic acid ligilactobacillus salivarius 83.77 35.32 5 PMID:23064348 -3.5.1.24 glycocholate bifidobacterium longum 85.0 85.0 1 PMID:16905539 -3.5.1.24 glycocholic acid clostridium perfringens 279.82 279.82 1 PMID:37883888 -3.5.1.24 glycocholic acid enterococcus faecalis 3250.0 3250.0 1 * -3.5.1.24 glycocholic acid lactiplantibacillus plantarum 774.57 774.57 1 PMID:37883888 -3.5.1.24 glycocholic acid ligilactobacillus salivarius 82.59 70.07 3 PMID:23064348 -3.5.1.24 glycodeoxycholic acid brevibacillus sp. 632.0 632.0 2 PMID:19142574;PMID:19669939 -3.5.1.24 glycodeoxycholic acid enterococcus faecalis 3013.0 3013.0 1 * -3.5.1.24 glycodeoxycholic acid lactiplantibacillus plantarum 88.13 88.13 1 * -3.5.1.24 glycodeoxycholic acid ligilactobacillus salivarius 80.87 48.76 3 PMID:23064348 -3.5.1.24 leu-cholic acid clostridium perfringens 0.028 0.028 1 PMID:37883888 -3.5.1.24 leu-cholic acid lactiplantibacillus plantarum 0.7 0.7 1 PMID:37883888 -3.5.1.24 phe-cholic acid clostridium perfringens 0.0103 0.0103 1 PMID:37883888 -3.5.1.24 phe-cholic acid lactiplantibacillus plantarum 16.08 16.08 1 PMID:37883888 -3.5.1.24 taurochenodeoxycholic acid bacteroides thetaiotaomicron 0.072 0.072 1 PMID:32042200 -3.5.1.24 taurochenodeoxycholic acid bifidobacterium longum 0.077 0.077 1 PMID:32042200 -3.5.1.24 taurochenodeoxycholic acid enterococcus faecalis 6210.0 6210.0 1 * -3.5.1.24 taurochenodeoxycholic acid ligilactobacillus salivarius 93.11 91.53 3 PMID:23064348 -3.5.1.24 taurocholate bifidobacterium longum 76.0 76.0 1 PMID:16905539 -3.5.1.24 taurocholic acid bifidobacterium longum 0.115 0.115 1 PMID:32042200 -3.5.1.24 taurocholic acid clostridium perfringens 367.9 367.9 1 PMID:37883888 -3.5.1.24 taurocholic acid enterococcus faecalis 2500.0 2500.0 1 * -3.5.1.24 taurocholic acid lactiplantibacillus plantarum 13.4 13.4 1 PMID:37883888 -3.5.1.24 taurocholic acid ligilactobacillus salivarius 93.14 70.03 3 PMID:23064348 -3.5.1.24 taurodeoxycholic acid bacteroides thetaiotaomicron 0.215 0.215 1 PMID:32042200 -3.5.1.24 taurodeoxycholic acid bifidobacterium longum 0.058 0.058 1 PMID:32042200 -3.5.1.24 taurodeoxycholic acid enterococcus faecalis 2600.0 2600.0 1 * -3.5.1.24 taurodeoxycholic acid ligilactobacillus salivarius 99.43 83.15 3 PMID:23064348 -3.5.1.24 tauroursodeoxycholic acid bacteroides thetaiotaomicron 0.255 0.255 1 PMID:32042200 -3.5.1.24 tauroursodeoxycholic acid bifidobacterium longum 0.015 0.015 1 PMID:32042200 -3.5.1.24 tyr-cholic acid clostridium perfringens 0.245 0.245 1 PMID:37883888 -3.5.1.24 tyr-cholic acid lactiplantibacillus plantarum 25.78 25.78 1 PMID:37883888 -3.5.1.25 n-acetyl-d-galactosamine 6-phosphate escherichia coli 154.0 154.0 1 PMID:17567047 -3.5.1.25 n-acetyl-d-galactosamine-6-phosphate mycobacterium marinum 5.4 5.4 1 PMID:29728457 -3.5.1.25 n-acetyl-d-galactosamine-6-phosphate mycolicibacterium smegmatis 31.1 31.1 1 PMID:29728457 -3.5.1.25 n-acetyl-d-glucosamine 6-phosphate chitiniphilus shinanonensis 68.9 12.5 3 PMID:38724455 -3.5.1.25 n-acetyl-d-glucosamine 6-phosphate escherichia coli 177.0 94.0 8 PMID:17567047;PMID:9143339 -3.5.1.25 n-acetyl-d-glucosamine 6-phosphate thermotoga maritima 110.0 110.0 1 PMID:17567048 -3.5.1.25 n-acetyl-d-glucosamine 6-sulfate escherichia coli 64.0 43.5 2 PMID:17567047 -3.5.1.25 n-acetyl-d-glucosamine-6-phosphate mycobacterium marinum 36.8 36.8 1 PMID:29728457 -3.5.1.25 n-acetyl-d-glucosamine-6-phosphate mycolicibacterium smegmatis 91.1 55.9 2 PMID:29728457 -3.5.1.25 n-acetyl-d-glucosamine-6-phosphate staphylococcus aureus 345.0 345.0 1 PMID:30411345 -3.5.1.25 n-acetyl-d-glucosamine-6-sulfate mycobacterium marinum 6.0 6.0 1 PMID:29728457 -3.5.1.25 n-acetyl-d-glucosamine-6-sulfate mycolicibacterium smegmatis 33.2 33.2 1 PMID:29728457 -3.5.1.25 n-acetyl-d-mannosamine-6-phosphate mycobacterium marinum 18.2 18.2 1 PMID:29728457 -3.5.1.25 n-acetyl-d-mannosamine-6-phosphate mycolicibacterium smegmatis 70.6 70.6 1 PMID:29728457 -3.5.1.25 n-acetylglucosamine alteromonas sp. 0.63 0.3215 2 PMID:10804240 -3.5.1.25 n-acetylglucosamine vibrio cholerae serotype o1 25.0 25.0 1 PMID:10804240;PMID:8987551 -3.5.1.25 n-acetylglucosamine 6-phosphate alteromonas sp. 0.68 0.4 2 PMID:10804240 -3.5.1.25 n-acetylglucosamine 6-phosphate vibrio cholerae serotype o1 0.97 0.97 1 PMID:10804240;PMID:8987551 -3.5.1.25 n-acetylglucosamine 6-sulfate alteromonas sp. 0.34 0.20700000000000002 2 PMID:10804240 -3.5.1.25 n-acetylglucosamine 6-sulfate vibrio cholerae serotype o1 50.0 50.0 1 PMID:10804240;PMID:8987551 -3.5.1.25 n-formyl-d-glucosamine 6-phosphate escherichia coli 22.0 22.0 1 PMID:17567047 -3.5.1.25 n-thioacetyl-d-glucosamine 6-phosphate escherichia coli 128.0 11.0 3 PMID:17567047 -3.5.1.25 n-trifluoroacetyl-d-glucosamine 6-phosphate escherichia coli 2610.0 2610.0 1 PMID:17567047 -3.5.1.26 n4-(beta-n-acetyl-d-glucosaminyl)-l-asparagine elizabethkingia meningoseptica 16.0 16.0 2 PMID:17157318 -3.5.1.26 n4-(beta-n-acetylglucosaminyl)-l-asparagine homo sapiens 14.18 14.18 1 PMID:30901125 -3.5.1.28 1,6-anhydro-murnac-l-ala-gamma-d-glu-m-dap citrobacter freundii 25.0 25.0 1 PMID:19496566 -3.5.1.28 1,6-anhydro-murnac-l-ala-gamma-d-glu-m-dap-d-ala-d-ala citrobacter freundii 11.0 11.0 1 PMID:19496566 -3.5.1.28 4-o-beta-d-glcnac-1,6-anhydro-murnac-l-ala-gamma-d-glu-m-dap-d-ala-d-ala citrobacter freundii 0.4 0.4 1 PMID:19496566 -3.5.1.28 7-methoxycoumarin-4-yl-acetyl-ala-d-isogln-lys(2,4-dinitrophenyl)-d-ala-arg staphylococcus epidermidis 0.00159 0.00159 1 PMID:19284999 -3.5.1.28 7-methoxycoumarin-4-yl-acetyl-ala-d-isoglu-lys(2,4-dinitrophenyl)-d-ala-arg staphylococcus epidermidis 0.00163 0.00163 1 PMID:19284999 -3.5.1.29 2-(acetamidomethylene)succinate mesorhizobium loti 0.6 0.6 1 PMID:18476725 -3.5.1.29 2-(acetamidomethylene)succinate pseudomonas sp. 1.67 1.67 1 PMID:3972793 -3.5.1.29 alpha-(n-acetylaminomethylene)succinic acid mesorhizobium loti 307.3 307.3 1 PMID:18635903 -3.5.1.3 2-oxoglutaramate mus musculus 17.5 17.5 1 PMID:19596042 -3.5.1.3 2-oxoglutaramate solanum lycopersicum 72.7 72.7 1 PMID:24837359 -3.5.1.3 2-oxoglutaramate zea mays 63.1 56.95 2 PMID:24837359 -3.5.1.3 2-oxosuccinamate mus musculus 1.15 1.01 2 PMID:19596042 -3.5.1.3 gamma-monomethyl-2-oxoglutaramate mus musculus 134.5 134.5 1 PMID:19596042 -3.5.1.3 glutaramate mus musculus 8.8 6.45 2 PMID:19596042 -3.5.1.3 succinamate mus musculus 2.8 2.4 2 PMID:19596042 -3.5.1.32 4-aminobenzoyl-glutamate campylobacter jejuni 14.75 14.75 1 PMID:16303789 -3.5.1.32 hippurate campylobacter jejuni 98.73 50.065000000000005 2 PMID:16303789 -3.5.1.32 n-acetyl-l-alanine campylobacter jejuni 22.12 15.06 2 PMID:16303789 -3.5.1.32 n-acetylglycine campylobacter jejuni 10.18 6.14 2 PMID:16303789 -3.5.1.32 n-benzoylalanine campylobacter jejuni 81.0 55.19 2 PMID:16303789 -3.5.1.32 n-benzoylglutamate campylobacter jejuni 48.72 24.445 2 PMID:16303789 -3.5.1.32 n-benzoylmethionine campylobacter jejuni 57.13 29.865000000000002 2 PMID:16303789 -3.5.1.32 n-benzoylphenylalanine campylobacter jejuni 5.95 5.95 1 PMID:16303789 -3.5.1.32 n-benzoylvaline campylobacter jejuni 13.33 6.915 2 PMID:16303789 -3.5.1.33 n-acetyl-d-glucosamine cyclobacterium marinum 118.97 118.97 1 PMID:38141024 -3.5.1.36 alpha-ketoglutarate pseudomonas sp. 0.0178 0.0178 1 PMID:5470822 -3.5.1.38 l-asparagine streptomyces canarius 0.00068 0.00068 1 PMID:26691453 -3.5.1.38 l-aspartate streptomyces canarius 0.00025 0.00025 1 PMID:26691453 -3.5.1.38 l-glutamine streptomyces canarius 0.00075 0.00075 1 PMID:26691453 -3.5.1.4 2-aminobenzamide saccharolobus solfataricus 0.9 0.9 1 PMID:11453462 -3.5.1.4 2-chloro-n-(2,6-diethylphenyl)acetamide starkeya sp. yw6 33.1 33.1 1 PMID:30864436 -3.5.1.4 2-chloro-n-(2-methyl-6-ethylphenyl)acetamide starkeya sp. yw6 31.8 31.8 1 PMID:30864436 -3.5.1.4 2-hydroxybenzamide saccharolobus solfataricus 1.3 1.3 1 PMID:11453462 -3.5.1.4 2-nitroacetanilide delftia acidovorans 129.0 129.0 1 PMID:237757 -3.5.1.4 2-toluamide saccharolobus solfataricus 0.425 0.4 3 PMID:11453462;PMID:16243781;PMID:19478917 -3.5.1.4 3-indolacetamide saccharolobus solfataricus 1.8 1.8 1 PMID:11453462 -3.5.1.4 3-phenyl-propionamide saccharolobus solfataricus 12.82 12.82 1 PMID:19478917 -3.5.1.4 3-phenylpropionamide saccharolobus solfataricus 15.3 11.2 2 PMID:11453462;PMID:16243781 -3.5.1.4 4-aminobenzamide saccharolobus solfataricus 0.8 0.8 1 PMID:11453462 -3.5.1.4 4-guanidinobutyramide streptomyces sp. 55.6 55.6 1 PMID:24752846 -3.5.1.4 4-hydroxybenzamide saccharolobus solfataricus 1.9 1.5 2 PMID:11453462;PMID:16243781 -3.5.1.4 4-hydroxybenzoic acid 1-phenylethylidene hydrazide pseudonocardia acaciae 1200.0 1200.0 1 PMID:38886122 -3.5.1.4 4-nitrobenzamide saccharolobus solfataricus 0.8 0.8 1 PMID:16243781 -3.5.1.4 4-nitrophenylacetate delftia acidovorans 144.0 144.0 1 PMID:237757 -3.5.1.4 4-toluamide saccharolobus solfataricus 12.2 12.2 3 PMID:11453462;PMID:16243781 -3.5.1.4 4-trifluoromethylnicotinamide stutzerimonas stutzeri 1.74 1.74 1 PMID:36116312 -3.5.1.4 acetamide aeribacillus pallidus 2668.0 2668.0 1 PMID:17347819 -3.5.1.4 acetamide methylophilus methylotrophus 2.13 2.13 1 * -3.5.1.4 acetamide pseudomonas aeruginosa 790.0 81.755 4 PMID:110350;PMID:110589 -3.5.1.4 acetamide pyrococcus yayanosii 5051.0 5051.0 1 PMID:24430467 -3.5.1.4 acetamide rhodococcus erythropolis 20.2 10.205 2 PMID:18388476;PMID:29486967 -3.5.1.4 acetamide rhodococcus sp. (in: high g+c gram-positive bacteria) 305.0 305.0 1 PMID:17136368 -3.5.1.4 acetamide rhodococcus sp. n-771 20.2 20.2 1 PMID:19819352 -3.5.1.4 acetamide saccharolobus solfataricus 28.9 20.13 3 PMID:11453462;PMID:16243781;PMID:19478917 -3.5.1.4 acetamide streptomyces sp. 29.9 29.9 1 PMID:24752846 -3.5.1.4 acetanilide delftia acidovorans 134.0 134.0 1 PMID:237757 -3.5.1.4 acetate rhodococcus sp. (in: high g+c gram-positive bacteria) 47.4 47.4 1 PMID:17136368 -3.5.1.4 acetohydrazide pseudomonas aeruginosa 20.0 15.0 2 PMID:110350 -3.5.1.4 acetohydroxamate pseudomonas aeruginosa 14.0 14.0 1 PMID:110350 -3.5.1.4 acrylamide aeribacillus pallidus 38.7 19.38575 2 PMID:17347819;PMID:23096998 -3.5.1.4 acrylamide pyrococcus yayanosii 333.3 333.3 1 PMID:24430467 -3.5.1.4 acrylamide rhodococcus erythropolis 2.1 1.34 2 PMID:18388476;PMID:29486967 -3.5.1.4 acrylamide rhodococcus sp. n-771 2.1 2.1 1 PMID:19819352 -3.5.1.4 acrylamide saccharolobus solfataricus 8.3 8.3 1 PMID:11453462 -3.5.1.4 benzamide blastobacter sp. 0.00217 0.00217 1 PMID:10788365 -3.5.1.4 benzamide rhodococcus erythropolis 157.7 79.08999999999999 2 PMID:18388476;PMID:29486967 -3.5.1.4 benzamide rhodococcus sp. n-771 157.7 157.7 1 PMID:19819352 -3.5.1.4 benzamide saccharolobus solfataricus 1192.0 6.550000000000001 4 PMID:11453462;PMID:16156792;PMID:16243781;PMID:19478917 -3.5.1.4 butylparaben pseudonocardia acaciae 410.0 410.0 1 PMID:38886122 -3.5.1.4 butyramide rhodococcus erythropolis 2.04 2.04 1 PMID:18388476 -3.5.1.4 butyramide saccharolobus solfataricus 34.3 19.98 3 PMID:11453462;PMID:16243781;PMID:19478917 -3.5.1.4 chlorpropham starkeya sp. yw6 33.7 33.7 1 PMID:30864436 -3.5.1.4 cinnamamide saccharolobus solfataricus 769.0 769.0 1 PMID:16156792 -3.5.1.4 cyclohexanamide saccharolobus solfataricus 16.3 16.3 1 PMID:11453462 -3.5.1.4 cyclomaltohexaose saccharolobus solfataricus 11.9 11.9 1 PMID:19478917 -3.5.1.4 glutaramic acid blastobacter sp. 0.0372 0.0372 1 PMID:10788365 -3.5.1.4 hexanamide pyrococcus yayanosii 721.7 721.7 1 PMID:24430467 -3.5.1.4 hexanamide saccharolobus solfataricus 19.5 12.4 2 PMID:11453462;PMID:16243781 -3.5.1.4 indol-3-acetamide saccharolobus solfataricus 2.2 2.125 2 PMID:16243781;PMID:19478917 -3.5.1.4 isobutyramide rhodococcus erythropolis 5.68 5.68 1 PMID:18388476 -3.5.1.4 isobutyramide saccharolobus solfataricus 175.0 45.39 4 PMID:11453462;PMID:16156792;PMID:16243781;PMID:19478917 -3.5.1.4 isonicotinamide saccharolobus solfataricus 1.6 1.6 1 PMID:11453462 -3.5.1.4 ketoprofen amide saccharolobus solfataricus 887.0 887.0 1 PMID:18680459 -3.5.1.4 l-glutamine pyrococcus yayanosii 7216.0 7216.0 1 PMID:24430467 -3.5.1.4 l-prolinamide saccharolobus solfataricus 3.1 3.1 1 PMID:11453462 -3.5.1.4 lactamide saccharolobus solfataricus 10.7 10.7 1 PMID:11453462 -3.5.1.4 metacrylamide saccharolobus solfataricus 5.75 5.275 2 PMID:16243781;PMID:19478917 -3.5.1.4 methacrylamide saccharolobus solfataricus 2.9 2.9 1 PMID:11453462 -3.5.1.4 methylparaben pseudonocardia acaciae 600.0 600.0 1 PMID:38886122 -3.5.1.4 n-methylacetamide pseudomonas aeruginosa 890.0 445.54 2 PMID:110350 -3.5.1.4 n-methylpropionamide pseudomonas aeruginosa 0.3 0.3 1 PMID:110350 -3.5.1.4 nicotinamide saccharolobus solfataricus 6.4 4.0 2 PMID:11453462;PMID:16243781 -3.5.1.4 nicotinamide streptomyces sp. 5.6 5.6 1 PMID:24752846 -3.5.1.4 pentanamide saccharolobus solfataricus 26.8 23.65 2 PMID:11453462;PMID:16243781 -3.5.1.4 phenylacetate delftia acidovorans 147.0 147.0 1 PMID:237757 -3.5.1.4 picolinamide saccharolobus solfataricus 1.8 1.8 1 PMID:11453462 -3.5.1.4 propanil rhodococcus sp. c-1 0.28 0.28 1 PMID:39082634 -3.5.1.4 propanil starkeya sp. yw6 32.7 32.7 1 PMID:30864436 -3.5.1.4 propham starkeya sp. yw6 33.4 33.4 1 PMID:30864436 -3.5.1.4 propionamide pseudomonas aeruginosa 465.0 419.5 2 PMID:110350 -3.5.1.4 propionamide pseudomonas chlororaphis 10.5 10.5 1 PMID:16534982 -3.5.1.4 propionamide rhodococcus erythropolis 155.2 79.615 2 PMID:18388476;PMID:29486967 -3.5.1.4 propionamide rhodococcus sp. n-771 155.3 155.3 1 PMID:19819352 -3.5.1.4 propionamide saccharolobus solfataricus 181.0 92.4 4 PMID:11453462;PMID:16156792;PMID:16243781;PMID:19478917 -3.5.1.4 propionamide streptomyces sp. 28.6 28.6 1 PMID:24752846 -3.5.1.4 propionohydrazide pseudomonas aeruginosa 9.5 9.5 1 PMID:110350 -3.5.1.4 propionohydroxamate pseudomonas aeruginosa 22.0 22.0 1 PMID:110350 -3.5.1.4 propylparaben pseudonocardia acaciae 580.0 580.0 1 PMID:38886122 -3.5.1.4 succinamic acid blastobacter sp. 0.096 0.096 1 PMID:10788365 -3.5.1.41 (glcnac)3 bombyx mori 0.127 0.127 1 PMID:30755482 -3.5.1.41 (glcnac)4 bombyx mori 0.0932 0.0932 1 PMID:30755482 -3.5.1.41 (glcnac)5 bombyx mori 0.125 0.125 1 PMID:30755482 -3.5.1.41 (glcnac)6 bombyx mori 0.151 0.151 1 PMID:30755482 -3.5.1.41 (n-acetyl-d-glucosamine)2 colletotrichum lindemuthianum 8.52 8.52 1 PMID:8987657 -3.5.1.41 (n-acetyl-d-glucosamine)3 colletotrichum lindemuthianum 5.94 5.94 1 PMID:8987657 -3.5.1.41 (n-acetyl-d-glucosamine)4 colletotrichum lindemuthianum 96.9 75.0 2 PMID:10913295;PMID:8987657 -3.5.1.41 (n-acetyl-d-glucosamine)5 colletotrichum lindemuthianum 83.8 49.35 6 PMID:10518926;PMID:10913295;PMID:8987657 -3.5.1.41 2-acetamido-2-deoxy-beta-d-glucopyranosyl-(1-4)-2-acetamido-2-deoxy-beta-d-glucopyranosyl-(1-4)-2-bromoacetamido-2-deoxy-beta-d-glucopyranosyl-(1-4)-2-acetamido-2-deoxy-d-glucose colletotrichum lindemuthianum 31.0 31.0 1 PMID:16878976 -3.5.1.41 2-acetamido-2-deoxy-beta-d-glucopyranosyl-(1-4)-2-acetamido-2-deoxy-beta-d-glucopyranosyl-(1-4)-2-chloroacetamido-2-deoxy-beta-d-glucopyranosyl-(1-4)-2-acetamido-2-deoxy-d-glucose colletotrichum lindemuthianum 47.0 47.0 1 PMID:16878976 -3.5.1.41 2-acetamido-2-deoxy-beta-d-glucopyranosyl-(1-4)-2-acetamido-2-deoxy-beta-d-glucopyranosyl-(1-4)-2-fluoroacetamido-2-deoxy-beta-d-glucopyranosyl-(1-4)-2-acetamido-2-deoxy-d-glucose colletotrichum lindemuthianum 68.0 68.0 1 PMID:16878976 -3.5.1.41 colloidal chitin bombyx mori 0.0002 0.0002 1 PMID:30755482 -3.5.1.41 ethylene glycol chitin bombyx mori 0.0016 0.0016 1 PMID:30755482 -3.5.1.41 glcnac-beta-(1-4)-glcnac colletotrichum lindemuthianum 11.0 11.0 1 PMID:12775215 -3.5.1.41 glcnac-beta-(1-4)-glcnac sinorhizobium meliloti 0.38 0.38 1 PMID:28284052 -3.5.1.41 glcnac-beta-(1-4)-glcnac-beta-(1-4)-glcn-beta-(1-4)-glcnac sinorhizobium meliloti 0.45 0.45 1 PMID:28284052 -3.5.1.41 glcnac-beta-(1-4)-glcnac-beta-(1-4)-glcnac colletotrichum lindemuthianum 6.0 6.0 1 PMID:12775215 -3.5.1.41 glcnac-beta-(1-4)-glcnac-beta-(1-4)-glcnac-beta-(1-4)-glcnac colletotrichum lindemuthianum 7.0 7.0 1 PMID:12775215 -3.5.1.41 glcnac-beta-(1-4)-glcnac-beta-(1-4)-glcnac-beta-(1-4)-glcnac-beta-(1-4)-glcnac colletotrichum lindemuthianum 7.0 7.0 1 PMID:12775215 -3.5.1.41 glcnac-beta-(1-4)-glcnac-beta-(1-4)-glcnac-beta-(1-4)-glcnac-beta-(1-4)-glcnac-beta-(1-4)-glcnac colletotrichum lindemuthianum 5.4 5.4 1 PMID:12775215 -3.5.1.41 glcnacbeta(1-4)glcnac colletotrichum lindemuthianum 11.0 11.0 1 PMID:16878976 -3.5.1.41 glcnacbeta(1-4)glcnacbeta(1-4)glcnac colletotrichum lindemuthianum 6.0 3.765 2 PMID:16878976 -3.5.1.41 glcnacbeta(1-4)glcnacbeta(1-4)glcnacbeta(1-4)glcnac colletotrichum lindemuthianum 7.0 7.0 1 PMID:16878976 -3.5.1.41 glcnacglcnacglcnacglcn colletotrichum lindemuthianum 58.7 58.7 1 PMID:10913295 -3.5.1.41 glcnacglcnglcnacglcnac colletotrichum lindemuthianum 57.5 57.5 1 PMID:10913295 -3.5.1.41 glcnglcnacglcnacglcnac colletotrichum lindemuthianum 22.7 22.7 1 PMID:10913295 -3.5.1.41 glycol chitin aspergillus nidulans 6.25 6.25 1 PMID:19760058 -3.5.1.41 glycol chitin colletotrichum lindemuthianum 27.2 27.2 1 PMID:8987657 -3.5.1.41 penta-n-acetyl-chitopentaose aspergillus nidulans 1.4 1.4 1 PMID:28496100 -3.5.1.42 beta-nicotinamide d-ribonucleotide escherichia coli 4.1 4.1 1 PMID:24530526 -3.5.1.42 beta-nicotinamide d-ribonucleotide oceanobacillus iheyensis 0.38 0.38 1 PMID:24340054 -3.5.1.42 nicotinamide mononucleotide agrobacterium fabrum 8.7 8.7 1 PMID:28388636 -3.5.1.42 nicotinamide mononucleotide escherichia coli 3.3 3.3 1 PMID:21953451 -3.5.1.42 nicotinamide mononucleotide shewanella oneidensis 3.3 3.3 1 PMID:21953451 -3.5.1.44 cbz-gln-gly chryseobacterium proteolyticum 9.05 9.05 1 PMID:38657166 -3.5.1.46 6-aminohexanoate dimer paenarthrobacter ureafaciens 1.17 1.17 1 PMID:27529542 -3.5.1.46 6-aminohexanoate trimer flavobacterium sp. 2.0 2.0 1 PMID:7262074 -3.5.1.46 n-(6-aminohexanoyl)-6-aminohexanoate flavobacterium sp. 19.0 2.7 5 PMID:7262074;PMID:8515236 -3.5.1.46 n-(6-aminohexanoyl)-6-aminohexanoate pseudomonas sp. 9.2 9.2 1 PMID:8515236 -3.5.1.48 7-(nalpha-acetyl-glycyl-l-alanyl-nepsilon-acetyl-l-lysyl)amino-4-methylcoumarin danio rerio 0.00033 0.00033 1 PMID:28516954 -3.5.1.48 7-(nalpha-acetyl-glycyl-l-alanyl-nepsilon-acetyl-l-lysyl)amino-4-methylcoumarin homo sapiens 0.00038 0.00038 1 PMID:28516954 -3.5.1.48 7-(nalpha-acetyl-l-arginyl-glycyl-nepsilon-acetyl-l-lysyl)-amino-4-methylcoumarin danio rerio 0.0015 0.0015 1 PMID:28516954 -3.5.1.48 7-(nalpha-acetyl-l-arginyl-glycyl-nepsilon-acetyl-l-lysyl)-amino-4-methylcoumarin homo sapiens 0.008 0.008 1 PMID:28516954 -3.5.1.48 acetylcadaverine danio rerio 0.37 0.37 1 PMID:28516954 -3.5.1.48 acetylcadaverine homo sapiens 0.14 0.14 1 PMID:28516954 -3.5.1.48 acetylputrescine danio rerio 0.7 0.7 1 PMID:28516954 -3.5.1.48 acetylputrescine homo sapiens 0.35 0.35 1 PMID:28516954 -3.5.1.48 n-(8-aminooctyl)acetamide danio rerio 0.21 0.21 1 PMID:28516954 -3.5.1.48 n-(8-aminooctyl)acetamide homo sapiens 0.1 0.1 1 PMID:28516954 -3.5.1.48 n-butylacetamide danio rerio 0.06 0.06 1 PMID:28516954 -3.5.1.48 n1,n8-diacetylspermidine danio rerio 0.48 0.48 1 PMID:28516954 -3.5.1.48 n1,n8-diacetylspermidine homo sapiens 0.14 0.14 1 PMID:28516954 -3.5.1.48 n1-acetylspermine homo sapiens 0.011 0.011 1 PMID:28516954 -3.5.1.48 n8-acetylspermidine danio rerio 0.58 0.58 1 PMID:28516954 -3.5.1.48 n8-acetylspermidine homo sapiens 0.28 0.28 1 PMID:28516954 -3.5.1.48 nalpha,nepsilon-diacetyl-l-lysinamide homo sapiens 0.0092 0.0092 1 PMID:28516954 -3.5.1.48 nalpha-acetyl-l-alanyl-nepsilon-acetyl-l-lysyl-l-alaninamide danio rerio 0.013 0.013 1 PMID:28516954 -3.5.1.48 nalpha-acetyl-l-alanyl-nepsilon-acetyl-l-lysyl-l-alaninamide homo sapiens 0.0006 0.0006 1 PMID:28516954 -3.5.1.49 formamide methylophilus methylotrophus 60.7 60.7 1 * -3.5.1.5 urea canavalia ensiformis 5913.0 5913.0 1 * -3.5.1.5 urea klebsiella aerogenes 3500.0 3235.0 2 PMID:10913264 -3.5.1.53 n-carbamoylputrescine bacteroides thetaiotaomicron 0.8 0.8 1 PMID:37189741 -3.5.1.54 allophanate enterobacter cloacae 6.0 6.0 1 PMID:16597948 -3.5.1.54 allophanate granulibacter bethesdensis 18.2 18.2 1 PMID:23282241 -3.5.1.54 allophanate pseudomonas sp. 16.4 16.4 1 PMID:15901697 -3.5.1.54 malonamic acid pseudomonas sp. 0.1 0.1 1 PMID:15901697 -3.5.1.54 urea-1-carboxylate candida albicans 24.0 24.0 1 PMID:27452902 -3.5.1.54 urea-1-carboxylate granulibacter bethesdensis 18.0 16.5 2 PMID:27452902 -3.5.1.54 urea-1-carboxylate pseudomonas syringae pv. tomato 12.0 11.5 2 PMID:27452902 -3.5.1.54 urea-1-carboxylate saccharomyces cerevisiae 32.0 32.0 1 PMID:27452902 -3.5.1.56 formamide paracoccus sp. ssg05 0.5 0.5 1 PMID:32452120 -3.5.1.56 n,n-dimethylformamide paracoccus sp. ssg05 218.0 218.0 1 PMID:32452120 -3.5.1.56 n-ethylformamide paracoccus sp. ssg05 107.0 107.0 1 PMID:32452120 -3.5.1.56 n-methylformamide paracoccus sp. ssg05 185.0 185.0 1 PMID:32452120 -3.5.1.6 2-amino-3-ureidopropionic acid agrobacterium tumefaciens 0.15 0.15 1 PMID:19011069 -3.5.1.6 2-methyl-3-ureidopropionic acid agrobacterium tumefaciens 24.39 24.39 1 PMID:19011069 -3.5.1.6 2-phenyl-3-ureidopropionic acid agrobacterium tumefaciens 0.13 0.13 1 PMID:19011069 -3.5.1.6 2-ureidoethane phosphonic acid agrobacterium tumefaciens 0.23 0.23 1 PMID:19011069 -3.5.1.6 2-ureidoethanesulfonic acid agrobacterium tumefaciens 5.84 5.84 1 PMID:19011069 -3.5.1.6 3-methyl-3-ureidopropionic acid agrobacterium tumefaciens 0.2 0.2 1 PMID:19011069 -3.5.1.6 3-ureidopropanoate homo sapiens 0.47 0.39 2 PMID:29976570 -3.5.1.6 3-ureidopropionic acid agrobacterium tumefaciens 25.71 25.71 1 PMID:19011069 -3.5.1.6 n-acetyl-beta-alanine agrobacterium tumefaciens 3.93 3.93 1 PMID:21515096 -3.5.1.6 n-acetyl-l-alanine agrobacterium tumefaciens 0.89 0.89 1 PMID:21515096 -3.5.1.6 n-acetyl-l-methionine agrobacterium tumefaciens 0.15 0.15 1 PMID:21515096 -3.5.1.6 n-carbamoyl-5-aminopentanoate agrobacterium tumefaciens 2.28 2.28 1 PMID:21515096 -3.5.1.6 n-carbamoyl-alpha-amino-beta-alanine agrobacterium tumefaciens 0.15 0.15 1 PMID:21515096 -3.5.1.6 n-carbamoyl-alpha-methyl-beta-alanine agrobacterium tumefaciens 24.39 24.39 1 PMID:21515096 -3.5.1.6 n-carbamoyl-alpha-phenyl-beta-alanine agrobacterium tumefaciens 0.13 0.13 1 PMID:21515096 -3.5.1.6 n-carbamoyl-beta-alanine agrobacterium tumefaciens 25.71 25.71 1 PMID:21515096 -3.5.1.6 n-carbamoyl-beta-alanine lachancea kluyveri 5.3 5.3 1 PMID:17916556 -3.5.1.6 n-carbamoyl-beta-alanine rattus norvegicus 0.6 0.6 1 PMID:10989448 -3.5.1.6 n-carbamoyl-beta-homoalanine agrobacterium tumefaciens 0.21 0.21 1 PMID:21515096 -3.5.1.6 n-carbamoyl-ciliatine agrobacterium tumefaciens 0.23 0.23 1 PMID:21515096 -3.5.1.6 n-carbamoyl-d-ornithine agrobacterium tumefaciens 0.01 0.01 1 PMID:21515096 -3.5.1.6 n-carbamoyl-gaba agrobacterium tumefaciens 24.03 24.03 1 PMID:21515096 -3.5.1.6 n-carbamoyl-gamma-amino-beta-hydroxybutyric acid agrobacterium tumefaciens 1.95 1.95 1 PMID:21515096 -3.5.1.6 n-carbamoyl-glycine agrobacterium tumefaciens 21.88 21.88 1 PMID:21515096 -3.5.1.6 n-carbamoyl-homoisoserine agrobacterium tumefaciens 4.27 4.27 1 PMID:21515096 -3.5.1.6 n-carbamoyl-l-alanine agrobacterium tumefaciens 6.27 6.27 1 PMID:21515096 -3.5.1.6 n-carbamoyl-l-methionine agrobacterium tumefaciens 8.64 8.64 1 PMID:21515096 -3.5.1.6 n-carbamoyl-l-ornithine agrobacterium tumefaciens 0.08 0.08 1 PMID:21515096 -3.5.1.6 n-carbamoyl-l-phenylalanine agrobacterium tumefaciens 5.81 5.81 1 PMID:21515096 -3.5.1.6 n-carbamoyl-taurine agrobacterium tumefaciens 5.84 5.84 1 PMID:21515096 -3.5.1.6 n-formyl-l-methionine agrobacterium tumefaciens 23.03 23.03 1 PMID:21515096 -3.5.1.62 acetylcadaverine marinobacter subterrani 0.026 0.026 1 PMID:31436969 -3.5.1.62 acetylputrescine marinobacter subterrani 0.0078 0.0078 1 PMID:31436969 -3.5.1.62 acetylspermine marinobacter subterrani 0.007 0.007 1 PMID:31436969 -3.5.1.62 n1-acetylspermidine marinobacter subterrani 0.0038 0.0038 1 PMID:31436969 -3.5.1.62 n6-acetylspermidine marinobacter subterrani 0.0092 0.0086 2 PMID:31436969 -3.5.1.66 2-(hydroxymethyl)-3-(acetamidomethylene)succinate arthrobacter sp. 2.3 2.3 1 PMID:3972793 -3.5.1.70 penicillin dihydrof actinoplanes utahensis 4.2 4.2 1 PMID:17586674 -3.5.1.70 penicillin f actinoplanes utahensis 1.9 1.9 1 PMID:17586674 -3.5.1.70 penicillin g actinoplanes utahensis 2.2 2.2 1 PMID:17586674 -3.5.1.70 penicillin k actinoplanes utahensis 33.3 33.3 1 PMID:17586674 -3.5.1.70 penicillin v actinoplanes utahensis 70.3 70.3 1 PMID:17586674 -3.5.1.75 ethyl carbamate candida parapsilosis 2.91 2.91 1 PMID:39151849 -3.5.1.77 n-carbamoyl-d-p-hydroxyphenylglycine agrobacterium tumefaciens 14.88 7.88 5 PMID:12364584;PMID:16650857 -3.5.1.77 n-carbamoyl-d-p-hydroxyphenylglycine ralstonia pickettii 7.0 6.2 2 PMID:17121498;PMID:21360152 -3.5.1.77 n-carbamoyl-d-trp nitratireductor indicus 1.96 1.96 1 PMID:36541894 -3.5.1.78 glutathionylspermidine escherichia coli 2.1 2.1 1 PMID:7775463 -3.5.1.79 2-carboxybenzoylamine-d-phe-l-ala xanthobacter agilis 1.8 1.8 1 * -3.5.1.79 2-carboxybenzoylamine-d-phenylglycine-methylester xanthobacter agilis 4.7 4.7 1 * -3.5.1.79 2-carboxybenzoylamine-l-phe-l-ala xanthobacter agilis 2.3 2.3 1 * -3.5.1.81 n-acetyl-d-ala achromobacter xylosoxidans 229.0 229.0 1 PMID:21546325 -3.5.1.81 n-acetyl-d-leu achromobacter denitrificans 468.0 468.0 1 PMID:1368943 -3.5.1.81 n-acetyl-d-leucine achromobacter xylosoxidans 1225.0 1225.0 1 PMID:10705441 -3.5.1.81 n-acetyl-d-met achromobacter denitrificans 1040.0 1040.0 1 PMID:1368943 -3.5.1.81 n-acetyl-d-met achromobacter xylosoxidans 1826.0 1826.0 1 PMID:21546325 -3.5.1.81 n-acetyl-d-met alcaligenes faecalis 438.0 438.0 1 PMID:14736882 -3.5.1.81 n-acetyl-d-methionine variovorax paradoxus 57.53 57.53 1 * -3.5.1.81 n-acetyl-d-phe achromobacter denitrificans 877.0 877.0 1 PMID:1368943 -3.5.1.81 n-acetyl-d-phenylalanine microbacterium natoriense 41.0 41.0 1 PMID:22721690 -3.5.1.81 n-acetyl-d-trp achromobacter xylosoxidans 89.5 89.5 1 PMID:21546325 -3.5.1.81 n-chloroacetyl-d-val achromobacter denitrificans 382.0 382.0 1 PMID:1368943 -3.5.1.84 biuret rhizobium leguminosarum bv. viciae 11.9 7.95 2 PMID:9425231 -3.5.1.86 (r)-(+)-mandelamide pseudomonas putida 16.1 16.1 1 PMID:12670968 -3.5.1.86 (r)-(-)-mandelamide pseudomonas putida 10.2 10.2 1 * -3.5.1.86 (r)-2-aminophenylacetamide pseudomonas putida 25.0 25.0 1 PMID:19074156 -3.5.1.86 (r)-lactamide pseudomonas putida 43.0 43.0 1 PMID:19074156 -3.5.1.86 (r)-mandelamide pseudomonas putida 150.0 150.0 1 PMID:19074156 -3.5.1.86 (s)-(+)-mandelamide pseudomonas putida 7.73 4.4 3 PMID:12670968 -3.5.1.86 (s)-2-aminophenylacetamide pseudomonas putida 27.0 27.0 1 PMID:19074156 -3.5.1.86 (s)-lactamide pseudomonas putida 19.0 19.0 1 PMID:19074156 -3.5.1.86 (s)-mandelamide pseudomonas putida 150.0 116.0 2 PMID:19074156;PMID:28129982 -3.5.1.86 2-cyclohexylacetamide pseudomonas putida 1.1 1.1 1 PMID:19074156 -3.5.1.86 2-phenylacetamide pseudomonas putida 46.0 46.0 1 PMID:19074156 -3.5.1.86 acetamide pseudomonas putida 1.4 1.4 1 PMID:19074156 -3.5.1.86 butanamide pseudomonas putida 0.61 0.61 1 PMID:19074156 -3.5.1.86 caproamide pseudomonas putida 2.8 2.8 1 PMID:19074156 -3.5.1.86 cyclohexanecarboxamide pseudomonas putida 0.04 0.04 1 PMID:19074156 -3.5.1.86 pentanamide pseudomonas putida 2.0 2.0 1 PMID:19074156 -3.5.1.86 propanamide pseudomonas putida 4.6 4.6 1 PMID:19074156 -3.5.1.87 n-acetyl-l-alanine geobacillus stearothermophilus 27.86 27.86 1 PMID:20730754 -3.5.1.87 n-acetyl-l-methionine geobacillus stearothermophilus 2.26 2.26 1 PMID:20730754 -3.5.1.87 n-acetyl-l-phenylalanine geobacillus stearothermophilus 0.01 0.01 1 PMID:20730754 -3.5.1.87 n-acetyl-l-tyrosine geobacillus stearothermophilus 0.08 0.08 1 PMID:20730754 -3.5.1.87 n-acetyl-l-valine geobacillus stearothermophilus 0.08 0.08 1 PMID:20730754 -3.5.1.87 n-carbamoyl-glycine pseudomonas sp. on4a 7.56 7.56 1 PMID:19830420 -3.5.1.87 n-carbamoyl-l-alanine geobacillus stearothermophilus 48.96 48.96 1 PMID:20730754 -3.5.1.87 n-carbamoyl-l-alanine pseudomonas sp. on4a 6.11 6.11 1 PMID:19830420 -3.5.1.87 n-carbamoyl-l-cysteine pseudomonas sp. on4a 16.5 16.5 1 PMID:19830420 -3.5.1.87 n-carbamoyl-l-methionine geobacillus stearothermophilus 5.32 5.32 1 PMID:20730754 -3.5.1.87 n-carbamoyl-l-methionine paenarthrobacter aurescens 0.9 0.9 1 PMID:10194852 -3.5.1.87 n-carbamoyl-l-methionine pseudomonas sp. on4a 3.54 3.54 1 PMID:19830420 -3.5.1.87 n-carbamoyl-l-phenylalanine geobacillus stearothermophilus 0.16 0.16 1 PMID:20730754 -3.5.1.87 n-carbamoyl-l-thienylalanine paenarthrobacter aurescens 16.1 16.1 1 PMID:10194852 -3.5.1.87 n-carbamoyl-l-tryptophan paenarthrobacter aurescens 5.1 5.1 1 PMID:10194852 -3.5.1.87 n-carbamoyl-l-tyrosine geobacillus stearothermophilus 0.18 0.18 1 PMID:20730754 -3.5.1.87 n-carbamoyl-l-tyrosine paenarthrobacter aurescens 6.5 6.5 1 PMID:10194852 -3.5.1.87 n-carbamoyl-l-valine geobacillus stearothermophilus 0.84 0.84 1 PMID:20730754 -3.5.1.87 n-formyl-dl-tryptophan paenarthrobacter aurescens 5.0 5.0 1 PMID:10194852 -3.5.1.87 n-formyl-l-alanine geobacillus stearothermophilus 293.5 293.5 1 PMID:20730754 -3.5.1.87 n-formyl-l-methionine geobacillus stearothermophilus 839.1 839.1 1 PMID:20730754 -3.5.1.87 n-formyl-l-phenylalanine geobacillus stearothermophilus 12.12 12.12 1 PMID:20730754 -3.5.1.87 n-formyl-l-tyrosine geobacillus stearothermophilus 1.46 1.46 1 PMID:20730754 -3.5.1.87 n-formyl-l-valine geobacillus stearothermophilus 27.26 27.26 1 PMID:20730754 -3.5.1.88 dnak75-ribosome-nascent chain complex escherichia coli 0.05 0.05 1 PMID:34961771 -3.5.1.88 formyl-l-met-leu-p-nitroanilide homo sapiens 0.17 0.17 1 PMID:12924944 -3.5.1.88 formyl-maha homo sapiens 0.0831 0.0831 1 PMID:19236878 -3.5.1.88 formyl-mehq homo sapiens 0.00937 0.00937 1 PMID:19236878 -3.5.1.88 formyl-met-ala mycobacterium tuberculosis 5.0 5.0 1 PMID:18574247 -3.5.1.88 formyl-met-ala-his-ala-ala-gln homo sapiens 0.57 0.57 1 PMID:12924944 -3.5.1.88 formyl-met-ala-ser escherichia coli 103.0 34.0 3 PMID:12538898;PMID:29101077 -3.5.1.88 formyl-met-ala-ser haemophilus influenzae 322.0 322.0 1 PMID:12538898 -3.5.1.88 formyl-met-ala-ser helicobacter pylori 3.4 3.4 1 PMID:15194508 -3.5.1.88 formyl-met-ala-ser homo sapiens 0.0081 0.0081 1 PMID:14637138 -3.5.1.88 formyl-met-ala-ser leptospira interrogans 5.0 5.0 1 PMID:12127977 -3.5.1.88 formyl-met-ala-ser staphylococcus aureus 152.0 152.0 1 PMID:12538898 -3.5.1.88 formyl-met-ala-ser streptococcus pneumoniae 332.0 332.0 1 PMID:12538898 -3.5.1.88 formyl-met-ala-ser vibrio phage vp16t 5.3 3.95 2 PMID:29101077 -3.5.1.88 formyl-met-leu-p-nitroanilide escherichia coli 16.0 16.0 1 PMID:34961771 -3.5.1.88 formyl-met-leu-p-nitroanilide homo sapiens 0.00046 0.00046 1 PMID:14637138 -3.5.1.88 formyl-met-thr-gln-ser-his homo sapiens 1.5 1.5 1 PMID:12924944 -3.5.1.88 formyl-met-thr-met-his-thr-thr homo sapiens 2.2 2.2 1 PMID:12924944 -3.5.1.88 formyl-mfad homo sapiens 0.057 0.057 1 PMID:19236878 -3.5.1.88 formyl-mfhq homo sapiens 0.0134 0.0134 1 PMID:19236878 -3.5.1.88 formyl-mghq homo sapiens 0.0155 0.0155 1 PMID:19236878 -3.5.1.88 formyl-mlhq homo sapiens 0.00275 0.00275 1 PMID:19236878 -3.5.1.88 formyl-mlkl homo sapiens 0.0049 0.0049 1 PMID:19236878 -3.5.1.88 formyl-mmya homo sapiens 0.0646 0.0646 1 PMID:19236878 -3.5.1.88 formyl-mnfa homo sapiens 0.0502 0.0502 1 PMID:19236878 -3.5.1.88 formyl-mnpl homo sapiens 0.0211 0.0211 1 PMID:19236878 -3.5.1.88 formyl-mpql homo sapiens 0.0283 0.0283 1 PMID:19236878 -3.5.1.88 formyl-mrhq homo sapiens 0.0202 0.0202 1 PMID:19236878 -3.5.1.88 formyl-mthq homo sapiens 0.044 0.03585 2 PMID:19236878 -3.5.1.88 formyl-mtmh homo sapiens 0.0362 0.0362 1 PMID:19236878 -3.5.1.88 formyl-mtpm homo sapiens 0.0174 0.0174 1 PMID:19236878 -3.5.1.88 formyl-mvhq homo sapiens 0.00581 0.00581 1 PMID:19236878 -3.5.1.88 n-formyl-1-(1-naphthyl)ethylamine escherichia coli 0.45 0.45 1 * -3.5.1.88 n-formyl-3-amino-3-phenylpropionic acid escherichia coli 7.1 7.1 1 * -3.5.1.88 n-formyl-alaninol escherichia coli 0.22 0.22 1 * -3.5.1.88 n-formyl-alpha-methyl-phenylglycine amide escherichia coli 0.045 0.045 1 * -3.5.1.88 n-formyl-beta-thiaphenylalanyl-ala-leu-4-nitroanilide escherichia coli 26.0 26.0 1 PMID:10469501 -3.5.1.88 n-formyl-l-ala-l-ala-l-ala escherichia coli 5.7 5.7 1 PMID:9665853 -3.5.1.88 n-formyl-l-met-l-ala-l-ser staphylococcus epidermidis 140.0 140.0 1 PMID:20656778 -3.5.1.88 n-formyl-l-met-l-lys escherichia coli 197.0 197.0 1 PMID:9665853 -3.5.1.88 n-formyl-m-methoxyphenylalanine nitrile escherichia coli 1370.0 1370.0 1 * -3.5.1.88 n-formyl-met-ala escherichia coli 2100.0 1166.0 2 PMID:9610360;PMID:9665853 -3.5.1.88 n-formyl-met-ala mycobacterium tuberculosis 8.8 8.8 1 PMID:24142250 -3.5.1.88 n-formyl-met-ala salmonella enterica subsp. enterica serovar typhimurium 4.1 4.1 1 PMID:24142250 -3.5.1.88 n-formyl-met-ala-phe-tyr-beta-ala-arg escherichia coli 1030.0 1030.0 1 PMID:9888804 -3.5.1.88 n-formyl-met-ala-ser arabidopsis thaliana 75.0 22.0 3 PMID:11733990 -3.5.1.88 n-formyl-met-ala-ser bacillus subtilis 0.17 0.12000000000000001 2 PMID:11429456 -3.5.1.88 n-formyl-met-ala-ser chlamydia trachomatis 6.4 6.4 1 PMID:21719536 -3.5.1.88 n-formyl-met-ala-ser escherichia coli 210.0 210.0 1 PMID:9665853 -3.5.1.88 n-formyl-met-ala-ser leptospira interrogans 5.0 5.0 1 PMID:11976499 -3.5.1.88 n-formyl-met-ala-ser mycobacterium tuberculosis 3.6 3.6 1 PMID:21507054 -3.5.1.88 n-formyl-met-ala-ser solanum lycopersicum 15.0 15.0 1 PMID:11733990 -3.5.1.88 n-formyl-met-ala-ser trypanosoma cruzi 0.093 0.093 1 PMID:22209909 -3.5.1.88 n-formyl-met-leu-glu arabidopsis thaliana 9.2 5.1499999999999995 2 PMID:11733990 -3.5.1.88 n-formyl-met-leu-nh2 escherichia coli 1320.0 1300.0 2 PMID:10651644 -3.5.1.88 n-formyl-met-leu-p-nitroanilide escherichia coli 38.0 28.5 2 PMID:10469501;PMID:10651644 -3.5.1.88 n-formyl-met-leu-phe arabidopsis thaliana 0.7 0.7 1 PMID:11733990 -3.5.1.88 n-formyl-met-ser-asn-glu arabidopsis thaliana 11.0 6.45 2 PMID:11733990 -3.5.1.88 n-formyl-met-ser-asn-glu escherichia coli 175.0 175.0 1 PMID:9665853 -3.5.1.88 n-formyl-methionine escherichia coli 0.21 0.21 1 PMID:9665853 -3.5.1.88 n-formyl-nle-ala(nh2) escherichia coli 270.0 270.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-ala-ser arabidopsis thaliana 136.0 81.0 2 PMID:11733990 -3.5.1.88 n-formyl-nle-ala-ser escherichia coli 218.0 218.0 1 PMID:9665853 -3.5.1.88 n-formyl-nle-arg(nh2) arabidopsis thaliana 138.0 71.5 2 PMID:11733990 -3.5.1.88 n-formyl-nle-arg(nh2) escherichia coli 300.0 300.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-asn(nh2) escherichia coli 320.0 320.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-asp(nh2) arabidopsis thaliana 6.4 3.4000000000000004 2 PMID:11733990 -3.5.1.88 n-formyl-nle-asp(nh2) escherichia coli 120.0 120.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-gln(nh2) escherichia coli 280.0 280.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-glu(nh2) escherichia coli 200.0 200.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-gly(nh2) arabidopsis thaliana 1.4 1.4 1 PMID:11733990 -3.5.1.88 n-formyl-nle-gly(nh2) escherichia coli 260.0 260.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-his(nh2) escherichia coli 250.0 250.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-leu(nh2) arabidopsis thaliana 0.36 0.36 1 PMID:11733990 -3.5.1.88 n-formyl-nle-leu(nh2) escherichia coli 150.0 150.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-lys(nh2) escherichia coli 230.0 230.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-met(nh2) escherichia coli 190.0 190.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-nle(nh2) escherichia coli 210.0 210.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-phe(nh2) escherichia coli 200.0 200.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-pro(nh2) escherichia coli 150.0 150.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-ser(nh2) arabidopsis thaliana 51.0 30.5 2 PMID:11733990 -3.5.1.88 n-formyl-nle-ser(nh2) escherichia coli 170.0 170.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-thr(nh2) escherichia coli 180.0 180.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-trp(nh2) escherichia coli 130.0 130.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-tyr(nh2) escherichia coli 140.0 140.0 1 PMID:10373378 -3.5.1.88 n-formyl-nle-val(nh2) escherichia coli 160.0 160.0 1 PMID:10373378 -3.5.1.88 n-formyl-nva-ala-ser arabidopsis thaliana 18.0 18.0 1 PMID:11733990 -3.5.1.88 n-formyl-phe-ala-ser arabidopsis thaliana 0.6 0.6 1 PMID:11733990 -3.5.1.88 n-formyl-phe-tyr-phe-his-beta-ala-arg escherichia coli 204.0 204.0 1 PMID:9888804 -3.5.1.88 n-formyl-phenylalanine nitrile escherichia coli 880.0 880.0 1 * -3.5.1.88 n-formyl-phenylglycine escherichia coli 10.6 10.6 1 * -3.5.1.88 n-formyl-phenylglycine amide escherichia coli 227.0 227.0 1 * -3.5.1.88 n-formyl-phenylglycinol escherichia coli 6.3 6.1899999999999995 2 * -3.5.1.88 n-formyl-tert-leucine amide escherichia coli 0.15 0.15 1 * -3.5.1.88 n-formyl-thiaphenylalanyl-peptide escherichia coli 3.5 3.5 1 PMID:10469501 -3.5.1.88 n-formyl-valine nitrile escherichia coli 29.7 29.7 1 * -3.5.1.88 n-formylmethionylleucyl-p-nitroanilide escherichia coli 70.0 70.0 1 PMID:10651644 -3.5.1.88 proompa75-ribosome-nascent chain complex escherichia coli 0.26 0.26 1 PMID:34961771 -3.5.1.88 rnaseh75-ribosome-nascent chain complex escherichia coli 0.24 0.24 1 PMID:34961771 -3.5.1.88 tolb75-ribosome-nascent chain complex escherichia coli 0.04 0.04 1 PMID:34961771 -3.5.1.9 n-formyl-l-kynurenine bacillus anthracis 50.56 50.56 1 PMID:24942958 -3.5.1.9 n-formyl-l-kynurenine burkholderia cenocepacia 43.94 43.94 1 PMID:24942958 -3.5.1.9 n-formyl-l-kynurenine drosophila melanogaster 26.4 26.4 1 PMID:22690733 -3.5.1.9 n-formyl-l-kynurenine pseudomonas aeruginosa 114.2 114.2 1 PMID:24942958 -3.5.1.9 n-formyl-l-kynurenine saccharomyces cerevisiae 161.0 161.0 1 PMID:18205391 -3.5.1.93 4-(glutarylamino)benzoic acid pseudomonas sp. 0.16 0.16 1 PMID:21576250 -3.5.1.93 7-aminocephalosporanic acid bacillus subtilis 0.0485 0.0485 1 PMID:20572278 -3.5.1.93 adipyl-7-aminocephalosporanic acid pseudomonas sp. sy-77-1 0.49 0.49 1 PMID:14680829 -3.5.1.93 adipyl-7-aminodeacetoxycephalosporanic acid pseudomonas sp. sy-77-1 0.41 0.41 1 PMID:15174165 -3.5.1.93 adipyl-7-aminodesacetoxycephalosporanic acid pseudomonas sp. 0.46 0.42000000000000004 2 PMID:12198140;PMID:17922842 -3.5.1.93 cephalosporin c pseudomonas sp. 5.93 2.9724999999999997 2 PMID:21576250;PMID:7607251 -3.5.1.93 gamma-glu-cys-gly pseudomonas sp. 0.33 0.33 1 PMID:21576250 -3.5.1.93 glutaryl-7-aminocephalosporanic acid brevibacillus laterosporus 7.54 4.025 2 PMID:16469317 -3.5.1.93 glutaryl-7-aminocephalosporanic acid pseudomonas sp. 49.8 4.3 5 PMID:12198140;PMID:16151116;PMID:17922842;PMID:21576250;PMID:8702285 -3.5.1.93 glutaryl-7-aminocephalosporanic acid pseudomonas sp. 130 16.9 12.35 2 PMID:11782466;PMID:15200051 -3.5.1.93 glutaryl-7-aminocephalosporanic acid pseudomonas sp. sy-77-1 4.0 4.0 2 PMID:14680829;PMID:15174165 -3.5.1.93 glutaryl-alanyl-proline pseudomonas sp. 6.2 6.2 1 PMID:21576250 -3.5.1.93 glutaryl-egdppdladqg pseudomonas sp. 12.8 12.8 1 PMID:21576250 -3.5.1.93 glutaryl-gamma-glu-cys-gly pseudomonas sp. 3.2 3.2 1 PMID:21576250 -3.5.1.93 glutaryl-gdaadaadkg pseudomonas sp. 4.8 4.8 1 PMID:21576250 -3.5.1.93 glutaryl-gdpp pseudomonas sp. 13.8 13.8 1 PMID:21576250 -3.5.1.93 glutaryl-gdppdladqg pseudomonas sp. 13.2 13.2 1 PMID:21576250 -3.5.1.93 glutaryl-ggggaa pseudomonas sp. 1.36 1.36 1 PMID:21576250 -3.5.1.93 glutaryl-gggggk pseudomonas sp. 1.73 1.73 1 PMID:21576250 -3.5.1.93 glutaryl-glycine pseudomonas sp. 1.65 1.65 1 PMID:21576250 -3.5.1.93 glutaryl-glycyl-proline pseudomonas sp. 5.4 5.4 1 PMID:21576250 -3.5.1.93 glutaryl-tryptophan pseudomonas sp. 3.1 3.1 1 PMID:21576250 -3.5.1.93 glutarylaniline pseudomonas sp. 0.35 0.35 1 PMID:21576250 -3.5.1.93 succinyl-7-aminocephalosporanic acid pseudomonas sp. 1.28 1.28 1 PMID:21576250 -3.5.1.94 4-(gamma-glutamylamino)butanoate pseudomonas aeruginosa 233.7 233.7 1 PMID:34605433 -3.5.1.97 n-3-oxo-hexanoyl-l-homoserine lactone delftia sp. vm4 24.3 24.3 1 PMID:26384328 -3.5.1.97 n-3-oxo-octanoyl-l-homoserine lactone delftia sp. vm4 22.8 22.8 1 PMID:26384328 -3.5.1.97 n-hexanoyl-l-homoserine lactone delftia sp. vm4 33.2 33.2 1 PMID:26384328 -3.5.1.98 ac-khk(acetyl)k(acetyl)-7-amido-4-methylcoumarin homo sapiens 1.0 0.012 3 PMID:35970392 -3.5.1.98 ac-khk(acetyl)k(acetyl)-7-amido-4-methylcoumarin schistosoma mansoni 0.017 0.017 3 PMID:35970392 -3.5.1.98 ac-leu-gly-lys(ac)-7-amido-4-methylcoumarin plasmodium falciparum 0.19 0.19 1 PMID:19317450 -3.5.1.98 fluor de lys homo sapiens 0.29 0.037 3 PMID:16412385 -3.5.1.98 fluor de lys hdac substrate homo sapiens 0.0002 0.0002 1 PMID:18285338 -3.5.1.98 fluor de lys hdac8 substrate homo sapiens 1.2 0.468 4 PMID:19053282;PMID:21865040 -3.5.1.98 ggk(ac)ff homo sapiens 1.09 1.09 1 PMID:30496698 -3.5.1.98 gk(ac)f homo sapiens 1.88 1.88 1 PMID:30496698 -3.5.1.98 rggk(ac)ffr homo sapiens 1.53 1.53 1 PMID:30496698 -3.5.1.98 rhk(acetyl)k(acetyl)-fluorophore homo sapiens 1.2 0.9 3 PMID:16681389 -3.5.1.98 ryssrrk(ac)arpyml homo sapiens 0.92 0.92 1 PMID:30496698 -3.5.1.98 sqseeek(ac)ffrrfp homo sapiens 0.02 0.02 1 PMID:30496698 -3.5.1.98 srggk(ac)ffrr homo sapiens 2.28 2.28 1 PMID:30496698 -3.5.1.98 tysrggk(ac)ffrrfp homo sapiens 0.71 0.71 1 PMID:30496698 -3.5.1.98 tysrggk(ac)kseese homo sapiens 0.12 0.12 1 PMID:30496698 -3.5.1.98 ysrggk(ac)ffrrf homo sapiens 1.66 1.66 1 PMID:30496698 -3.5.1.99 (10e,12e)-9-hydroxyoctadeca-(10,12-dienoyl)-ethanolamine arabidopsis thaliana 4.13 4.13 1 PMID:30894416 -3.5.1.99 (10e,12e)-9-hydroxyoctadeca-(10,12-dienoyl)-ethanolamine rattus norvegicus 1.04 1.04 1 PMID:30894416 -3.5.1.99 (9z,12z)-n-2-hydroxyethyl-(9,12-octadecadienoyl)-ethanolamine arabidopsis thaliana 5.5 5.5 1 PMID:30894416 -3.5.1.99 (9z,12z)-n-2-hydroxyethyl-(9,12-octadecadienoyl)-ethanolamine rattus norvegicus 3.29 3.29 1 PMID:30894416 -3.5.1.99 arachidonoyl p-nitroanilide rattus norvegicus 0.48 0.48 1 PMID:11352748 -3.5.1.99 decanoyl p-nitroanilide rattus norvegicus 0.56 0.56 1 PMID:11352748 -3.5.1.99 heptanoyl p-nitroanilide rattus norvegicus 0.46 0.46 1 PMID:11352748 -3.5.1.99 lauroyl p-nitroanilide rattus norvegicus 0.46 0.46 1 PMID:11352748 -3.5.1.99 myristoyl p-nitroanilide rattus norvegicus 0.29 0.29 1 PMID:11352748 -3.5.1.99 nonanoyl p-nitroanilide rattus norvegicus 0.6 0.6 1 PMID:11352748 -3.5.1.99 octanoyl p-nitroanilide rattus norvegicus 0.73 0.73 1 PMID:11352748 -3.5.1.99 oleamide rattus norvegicus 9.0 6.15 4 PMID:10433686;PMID:10571985;PMID:9790682 -3.5.1.99 oleoyl methyl amide rattus norvegicus 1.9 1.9 1 PMID:10571985 -3.5.1.99 oleoyl methyl ester rattus norvegicus 0.17 0.17 1 PMID:10571985 -3.5.1.99 oleoyl p-nitroanilide rattus norvegicus 2.8 1.535 2 PMID:10571985;PMID:11352748 -3.5.1.99 palmitoyl p-nitroanilide rattus norvegicus 0.27 0.27 1 PMID:11352748 -3.5.1.99 palmitoylethanolamide medicago truncatula 0.17 0.17 1 PMID:38831473 -3.5.1.99 sn-1-palmitoyl-rac-glycerol medicago truncatula 1.2 1.2 1 PMID:38831473 -3.5.1.99 sn-2-palmitoylglycerol medicago truncatula 1.0 1.0 1 PMID:38831473 -3.5.2.10 creatinine pseudomonas putida 1340.0 252.0 3 PMID:20043918 -3.5.2.12 1,8-diazacyclotetradecane-2,9-dione flavobacterium sp. 8.0 8.0 1 * -3.5.2.12 1,8-diazacyclotetradecane-2,9-dione pseudomonas sp. 10.7 10.7 1 PMID:8515236 -3.5.2.12 6-amino-hexanoate cyclic dimer paenarthrobacter ureafaciens 4.97 4.97 1 PMID:19889645 -3.5.2.15 cyanuric acid neomoorella thermoacetica 10.6 10.6 1 PMID:22730121 -3.5.2.15 cyanuric acid paracidovorax citrulli 14.2 14.2 1 PMID:22730121 -3.5.2.15 cyanuric acid pseudomonas sp. 250.0 161.5 2 PMID:10427042;PMID:22730121 -3.5.2.15 cyanuric acid pseudomonas sp. adp 15.5 15.5 1 PMID:29523689 -3.5.2.16 dihydrouracil pseudomonas putida 9.14 9.14 1 PMID:17534563 -3.5.2.16 hydantoin pseudomonas putida 2.94 2.5235000000000003 2 PMID:17534563 -3.5.2.16 maleimide agrobacterium tumefaciens 163.3 163.3 1 PMID:14637160 -3.5.2.16 maleimide oreochromis niloticus 3950.0 3950.0 1 PMID:14637160 -3.5.2.16 maleimide pseudomonas putida 479.0 479.0 1 PMID:17534563 -3.5.2.16 maleimide sus scrofa 106.7 106.7 1 PMID:14637160 -3.5.2.16 phthalimide agrobacterium tumefaciens 7.67 7.67 1 PMID:14637160 -3.5.2.16 phthalimide oreochromis niloticus 428.3 428.3 1 PMID:14637160 -3.5.2.16 phthalimide sus scrofa 25.17 25.17 1 PMID:14637160 -3.5.2.16 succinimide pseudomonas putida 1494.0 1494.0 1 PMID:17534563 -3.5.2.17 5,6-diaminouracil glycine max 0.21 0.21 1 PMID:12779339 -3.5.2.17 5-hydroxyisourate glycine max 24.0 11.0 3 PMID:10567345;PMID:12481089;PMID:12779339 -3.5.2.17 5-hydroxyisourate klebsiella pneumoniae 172.0 172.0 1 PMID:21795808 -3.5.2.2 2-chlorobenzenehydantoin pseudomonas fluorescens 0.37 0.37 1 PMID:26821258 -3.5.2.2 4-hydroxyphenylhydantoin pseudomonas fluorescens 74.2 74.2 1 PMID:26821258 -3.5.2.2 d-5-benzylhydantoin sinorhizobium meliloti 2.0 2.0 1 PMID:19895890 -3.5.2.2 d-5-butylhydantoin sinorhizobium meliloti 3.0 3.0 1 PMID:19895890 -3.5.2.2 d-5-ethylhydantoin agrobacterium tumefaciens 37.3 24.9 5 PMID:16497383 -3.5.2.2 d-5-ethylhydantoin sinorhizobium meliloti 17.0 17.0 1 PMID:19895890 -3.5.2.2 d-5-isobutylhydantoin sinorhizobium meliloti 2.0 2.0 1 PMID:19895890 -3.5.2.2 d-5-isopropylhydantoin sinorhizobium meliloti 5.0 5.0 1 PMID:19895890 -3.5.2.2 d-5-methyl-thio-ethylhydantoin sinorhizobium meliloti 18.0 18.0 1 PMID:19895890 -3.5.2.2 d-5-methylhydantoin sinorhizobium meliloti 197.0 197.0 1 PMID:19895890 -3.5.2.2 d-5-methylthioethylhydantoin agrobacterium tumefaciens 92.6 12.6 5 PMID:16497383 -3.5.2.2 d-5-propylhydantoin sinorhizobium meliloti 6.0 6.0 1 PMID:19895890 -3.5.2.2 dihydrouracil bacillus sp. (in: firmicutes) 6.2 6.2 1 PMID:16284925 -3.5.2.2 dihydrouracil sinorhizobium meliloti 2.0 2.0 1 PMID:19895890 -3.5.2.2 dl-5-(p-hydroxyphenyl)hydantoin sinorhizobium meliloti 1.0 1.0 1 PMID:19895890 -3.5.2.2 dl-5-methyldihydrouracil sinorhizobium meliloti 1.0 1.0 1 PMID:19895890 -3.5.2.2 dl-6-isopropyldihydrouracil sinorhizobium meliloti 1.0 1.0 1 PMID:19895890 -3.5.2.2 dl-6-methyldihydrouracil sinorhizobium meliloti 8.0 8.0 1 PMID:19895890 -3.5.2.2 dl-hydroxyphenylhydantoin geobacillus stearothermophilus 18.0 18.0 1 PMID:15182184 -3.5.2.2 dl-p-hydroxyphenylhydantoin geobacillus stearothermophilus 18.0 18.0 1 * -3.5.2.2 hydantoin bacillus sp. (in: firmicutes) 3.04 3.04 1 PMID:16284925 -3.5.2.2 hydantoin bos taurus 450.0 450.0 1 PMID:13428761 -3.5.2.2 hydantoin geobacillus stearothermophilus 440.0 249.5 2 PMID:15182184 -3.5.2.2 hydantoin sinorhizobium meliloti 12.0 12.0 1 PMID:19895890 -3.5.2.2 hydrothymine bos taurus 7.0 7.0 1 PMID:13428761 -3.5.2.2 hydrouracil bos taurus 71.7 71.7 1 PMID:13428761 -3.5.2.2 indolmethylhydantoin pseudomonas fluorescens 1.43 1.43 1 PMID:26821258 -3.5.2.2 isobutylhydantoin pseudomonas fluorescens 391.0 391.0 1 PMID:26821258 -3.5.2.2 isopropylhydantoin pseudomonas fluorescens 77.3 77.3 1 PMID:26821258 -3.5.2.2 l-5-ethylhydantoin agrobacterium tumefaciens 0.44 0.061 5 PMID:16497383 -3.5.2.2 l-5-methylthioethylhydantoin agrobacterium tumefaciens 11.4 3.9 5 PMID:16497383 -3.5.2.2 phenylmethylhydantoin pseudomonas fluorescens 2.91 2.91 1 PMID:26821258 -3.5.2.20 isatin burkholderia sp. ido3 95.5 95.5 1 * -3.5.2.20 isatin ralstonia solanacearum 88.0 88.0 1 PMID:30166577 -3.5.2.20 isatin roseibium aggregatum 80.0 80.0 1 PMID:30166577 -3.5.2.3 (s)-dihydroorotate bacillus anthracis 1.9 1.9 1 PMID:27499369 -3.5.2.3 (s)-dihydroorotate leishmania donovani 1.1 1.1 1 PMID:27650727 -3.5.2.3 (s)-dihydroorotate staphylococcus aureus 1.87 1.71 2 PMID:23246866 -3.5.2.3 dihydro-dl-orotate escherichia coli 127.0 127.0 1 PMID:6142052 -3.5.2.3 l-carbamoylaspartate crithidia fasciculata 0.653 0.653 1 PMID:1976382 -3.5.2.3 l-carbamoylaspartate plasmodium berghei 0.653 0.653 1 PMID:1976382 -3.5.2.3 l-dihydroorotate crithidia fasciculata 4.31 4.31 1 PMID:1976382 -3.5.2.3 l-dihydroorotate plasmodium berghei 4.31 2.2464999999999997 2 PMID:1976382 -3.5.2.3 l-dihydroorotate plasmodium falciparum 1.492 1.492 1 PMID:18082626 -3.5.2.3 n-(aminocarbonyl)-l-aspartic acid escherichia coli 181.1 181.1 1 PMID:17711307 -3.5.2.3 n-(aminocarbonyl)-l-aspartic acid plasmodium falciparum 0.073 0.073 1 PMID:18082626 -3.5.2.3 n-carbamoyl-dl-aspartate escherichia coli 195.0 195.0 1 PMID:6142052 -3.5.2.3 n-carbamoyl-l-aspartate aquifex aeolicus 62.3 62.3 1 PMID:27746403 -3.5.2.3 n-carbamoyl-l-aspartate bacillus anthracis 2.1 2.1 1 PMID:27499369 -3.5.2.3 n-carbamoyl-l-aspartate leishmania donovani 2.1 2.1 1 PMID:27650727 -3.5.2.3 n-carbamoyl-l-aspartate staphylococcus aureus 2.48 2.19 2 PMID:23246866 -3.5.2.5 allantoin phaseolus vulgaris 420.0 310.85 2 PMID:18251875 -3.5.2.6 (2s,5r,6r)-6-[[(2r)-2-carboxy-2-thiophen-3-ylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid escherichia coli 8.2 8.2 1 PMID:15561863 -3.5.2.6 (2s,5r,6r)-6-[[(2r)-2-carboxy-2-thiophen-3-ylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid klebsiella pneumoniae 84.0 84.0 1 PMID:15561863 -3.5.2.6 (6r,7r)-3-[(acetyloxy)methyl]-7-(formylamino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate enterobacter cloacae 1180.0 1180.0 1 PMID:19243936 -3.5.2.6 (6r,7r)-3-[(acetyloxy)methyl]-7-(formylamino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate escherichia coli 1.02 1.02 1 PMID:19243936 -3.5.2.6 (6r,7r)-3-[(acetyloxy)methyl]-7-(hydroxyamino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate enterobacter cloacae 1.6 1.6 1 PMID:19243936 -3.5.2.6 (6r,7r)-3-[(acetyloxy)methyl]-7-[[(2e)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid providencia stuartii 1.5 1.5 1 PMID:15328132 -3.5.2.6 (6r,7r)-3-[(acetyloxy)methyl]-7-[formyl(hydroxy)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate enterobacter cloacae 0.32 0.32 1 PMID:19243936 -3.5.2.6 (6r,7r)-3-[(acetyloxy)methyl]-7-[hydroxy(phenylacetyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate enterobacter cloacae 0.49 0.49 1 PMID:19243936 -3.5.2.6 (6r,7r)-3-[(acetyloxy)methyl]-7-[hydroxy(phenylacetyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate escherichia coli 0.121 0.121 1 PMID:19243936 -3.5.2.6 (6r,7r)-3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate enterobacter cloacae 0.46 0.46 1 PMID:19243936 -3.5.2.6 (6r,7r)-3-[(acetyloxy)methyl]-8-oxo-7-[(thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate enterobacter cloacae 690.0 690.0 1 PMID:19243936 -3.5.2.6 (6r,7r)-3-[(acetyloxy)methyl]-8-oxo-7-[(thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate escherichia coli 1.81 1.81 1 PMID:19243936 -3.5.2.6 (6r,7s)-3-[(3-carboxy-4-nitro-phenyl)sulfanylmethyl]-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo-[4.2.0]-oct-2-ene-2-carboxylic acid escherichia coli 1.6 1.6 1 PMID:18031291 -3.5.2.6 (6r,7z)-3-[(acetyloxy)methyl]-7-(hydroxyimino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate enterobacter cloacae 2.56 2.56 1 PMID:19243936 -3.5.2.6 (6r,7z)-7-(hydroxyimino)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 5,5-dioxide enterobacter cloacae 0.54 0.54 1 PMID:19243936 -3.5.2.6 3-([3-[benzyl(methyl)amino]-3-oxopropanoyl]oxy)benzoic acid enterobacter cloacae 0.33 0.33 1 PMID:19932622 -3.5.2.6 3-([3-dibenzylamino-3-oxopropanoyl]oxy)benzoic acid enterobacter cloacae 0.25 0.25 1 PMID:19932622 -3.5.2.6 3-([[(2r)-3-(benzylamino)-2-methoxy-3-oxopropanoyl]oxy]methyl)benzoic acid enterobacter cloacae 2.9 2.9 1 PMID:19932622 -3.5.2.6 3-([[(2r)-3-(benzylamino)-2-methyl-3-oxopropanoyl]oxy]methyl)benzoic acid enterobacter cloacae 1.17 1.17 1 PMID:19932622 -3.5.2.6 3-([[(2s)-3-(benzylamino)-2-methoxy-3-oxopropanoyl]oxy]methyl)benzoic acid enterobacter cloacae 7.4 7.4 1 PMID:19932622 -3.5.2.6 3-([[(2s)-3-(benzylamino)-2-methyl-3-oxopropanoyl]oxy]methyl)benzoic acid enterobacter cloacae 6.6 6.6 1 PMID:19932622 -3.5.2.6 3-([[2-benzyl-3-oxo-3-(benzylamino)propanoyl]oxy]methyl)benzoic acid enterobacter cloacae 0.05 0.05 1 PMID:19932622 -3.5.2.6 3-([n-(phenylacetyl)glycyl]oxy)benzoic acid enterobacter cloacae 125.0 75.0 2 PMID:14992604 -3.5.2.6 3-([n-[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]glycyl]oxy)benzoic acid enterobacter cloacae 19.0 15.0 2 PMID:14992604 -3.5.2.6 3-[2-(2-aminothiazol-4-yl)2-(z)-methoxyiminoacetylglycyl]oxybenzoic acid enterobacter cloacae 19.0 15.0 2 PMID:14992604 -3.5.2.6 3-[[(2s)-2-hydroxy-3-phenylpropanoyl]oxy]benzoic acid enterobacter cloacae 6.9 6.9 1 PMID:21087009 -3.5.2.6 3-nitrophenyl (2s)-2-hydroxy-3-phenylpropanoate enterobacter cloacae 10.9 10.9 1 PMID:21087009 -3.5.2.6 6-aminopenicillanic acid escherichia coli 659.0 659.0 1 PMID:7822311 -3.5.2.6 6-beta-iodopenicillanate elizabethkingia meningoseptica 300.0 300.0 1 * -3.5.2.6 7-(thienyl-2-acetamido)-3-[2-(4-,n,n-dimethylaminophenylazo)pyridinium-methyl]-3-cephem-4-carboxylic acid bacillus licheniformis 667.0 667.0 1 PMID:1974463 -3.5.2.6 7-(thienyl-2-acetamido)-3-[2-(4-n,n-dimethylaminophenylazo)pyridinium-methyl]-3-cephem-4-carboxylic acid escherichia coli 50.0 50.0 1 PMID:9735103 -3.5.2.6 amoxicillin acinetobacter bereziniae 15.2 15.2 1 PMID:22508298 -3.5.2.6 amoxicillin enterobacter cloacae 816.0 816.0 1 PMID:8807798 -3.5.2.6 amoxicillin klebsiella pneumoniae 532.5 277.75 2 PMID:18316524;PMID:29228168 -3.5.2.6 amoxicillin mycobacterium tuberculosis 5.67 5.67 1 PMID:17915954 -3.5.2.6 amoxicillin mycolicibacterium smegmatis 1.77 1.77 1 PMID:28421415 -3.5.2.6 amoxicillin pseudomonas aeruginosa 10.0 10.0 1 PMID:16127048 -3.5.2.6 amoxicillin pseudomonas luteola 21.0 21.0 1 PMID:19884377 -3.5.2.6 amoxicillin riemerella anatipestifer 11.0 11.0 1 PMID:35580446 -3.5.2.6 amoxicillin shouchella clausii 85.0 85.0 1 PMID:17846134 -3.5.2.6 amoxycillin escherichia coli 910.0 910.0 1 PMID:8056282 -3.5.2.6 amoxycillin serratia fonticola 460.0 460.0 1 PMID:9300809 -3.5.2.6 ampicilin shouchella lehensis 0.042 0.042 1 PMID:34502284 -3.5.2.6 ampicillin achromobacter sp. sallbros1 3.3 3.3 1 PMID:22290947 -3.5.2.6 ampicillin acinetobacter baumannii 426.66 396.66 3 PMID:16189095;PMID:16495258;PMID:37095236 -3.5.2.6 ampicillin acinetobacter baylyi 0.17 0.17 1 PMID:17403709 -3.5.2.6 ampicillin acinetobacter bereziniae 1.0 1.0 1 PMID:22508298 -3.5.2.6 ampicillin acinetobacter sp. 357.0 357.0 1 PMID:20086146 -3.5.2.6 ampicillin aeromonas enteropelogenes 0.63 0.63 1 PMID:20124004 -3.5.2.6 ampicillin aeromonas sobria 1.1 0.6165 2 PMID:8998985;PMID:9182099 -3.5.2.6 ampicillin bacillus cereus 5400.0 5400.0 1 PMID:10209286 -3.5.2.6 ampicillin bacillus licheniformis 2240.0 2240.0 1 PMID:1974463 -3.5.2.6 ampicillin bacteroides fragilis 75.0 75.0 1 PMID:9126607 -3.5.2.6 ampicillin brachyspira pilosicoli 6.6 6.6 1 PMID:18212108 -3.5.2.6 ampicillin burkholderia cenocepacia 70.0 70.0 1 PMID:19075063 -3.5.2.6 ampicillin burkholderia pseudomallei 0.54 0.54 1 PMID:15793160 -3.5.2.6 ampicillin chryseobacterium indologenes 10.3 10.3 1 PMID:17470648 -3.5.2.6 ampicillin citrobacter freundii 19.0 19.0 1 PMID:18765691 -3.5.2.6 ampicillin enterobacter cloacae 14.0 7.265 2 PMID:16189133;PMID:18312599 -3.5.2.6 ampicillin escherichia coli 3660.68 181.85 20 PMID:10438473;PMID:15215122;PMID:15561863;PMID:16189104;PMID:16251324;PMID:18031291;PMID:25324420;PMID:35175332;PMID:37170014;PMID:7822311 -3.5.2.6 ampicillin fusobacterium nucleatum 45.0 45.0 2 PMID:16870757 -3.5.2.6 ampicillin janthinobacterium lividum 480.0 480.0 1 PMID:15561856 -3.5.2.6 ampicillin klebsiella aerogenes 5.4 5.4 1 PMID:18160520 -3.5.2.6 ampicillin klebsiella pneumoniae 955.0 447.0 5 PMID:15561863;PMID:19477418;PMID:21911565;PMID:25324420;PMID:29228168 -3.5.2.6 ampicillin kluyvera ascorbata 7.0 7.0 1 PMID:17196371 -3.5.2.6 ampicillin metapseudomonas otitidis 190.0 190.0 1 PMID:25512428 -3.5.2.6 ampicillin moraxella catarrhalis 33.0 32.5 2 PMID:1396750 -3.5.2.6 ampicillin morganella morganii subsp. morganii 0.065 0.06 6 PMID:16189095;PMID:16495258 -3.5.2.6 ampicillin mycobacterium tuberculosis 18.5 14.75 2 PMID:16870770;PMID:17915954 -3.5.2.6 ampicillin mycolicibacterium smegmatis 9.62 9.62 1 PMID:28421415 -3.5.2.6 ampicillin pectobacterium carotovorum 5.0 5.0 1 PMID:18443127 -3.5.2.6 ampicillin plasmid pbg66 1085.0 1085.0 1 PMID:19812041 -3.5.2.6 ampicillin plasmid pgem-t-easy 220.0 190.0 2 PMID:19860471 -3.5.2.6 ampicillin plasmid rgn238 357.0 357.0 1 PMID:20086146 -3.5.2.6 ampicillin providencia stuartii 18.0 18.0 1 PMID:15328132 -3.5.2.6 ampicillin pseudomonas aeruginosa 1170.0 190.0 11 PMID:11148033;PMID:15561840;PMID:18362187;PMID:18559652;PMID:18644957;PMID:20974864;PMID:21041509;PMID:21149620 -3.5.2.6 ampicillin pseudomonas fluorescens 0.65 0.65 1 PMID:18312599 -3.5.2.6 ampicillin pseudomonas putida 560.0 289.0 2 PMID:12709317;PMID:18757180 -3.5.2.6 ampicillin psychrobacter immobilis 6.0 3.5 2 PMID:18312599;PMID:9063463 -3.5.2.6 ampicillin riemerella anatipestifer 15.0 15.0 1 PMID:35580446 -3.5.2.6 ampicillin serratia fonticola 155.0 82.25 2 PMID:17875998;PMID:21876065 -3.5.2.6 ampicillin serratia marcescens 0.46 0.46 1 PMID:18312599 -3.5.2.6 ampicillin shewanella algae 8.0 8.0 1 PMID:15105119 -3.5.2.6 ampicillin shigella sonnei 36.9 36.9 1 PMID:18955524 -3.5.2.6 ampicillin staphylococcus aureus 550.0 355.0 5 PMID:10209286;PMID:1605608 -3.5.2.6 ampicillin stenotrophomonas maltophilia 580.0 550.0 2 PMID:14573595;PMID:9559809 -3.5.2.6 ampicillin synthetic construct 3100.0 2044.5 2 PMID:19351161 -3.5.2.6 azlocillin pseudomonas aeruginosa 78.0 78.0 1 PMID:18559652 -3.5.2.6 azlocillin stenotrophomonas maltophilia 37.0 37.0 1 PMID:9559809 -3.5.2.6 aztreonam achromobacter sp. sallbros1 0.01 0.01 1 PMID:22290947 -3.5.2.6 aztreonam burkholderia cenocepacia 30.0 30.0 1 PMID:19075063 -3.5.2.6 aztreonam enterobacter cloacae 707.0 707.0 1 PMID:8807798 -3.5.2.6 aztreonam escherichia coli 84.0 42.2 2 PMID:10438473;PMID:15561863 -3.5.2.6 aztreonam klebsiella aerogenes 4.7 4.7 1 PMID:18160520 -3.5.2.6 aztreonam klebsiella pneumoniae 100.0 2.0 3 PMID:15561863;PMID:18316524;PMID:21911565 -3.5.2.6 aztreonam kluyvera ascorbata 0.24 0.24 1 PMID:17196371 -3.5.2.6 aztreonam providencia stuartii 9.0 9.0 1 PMID:15328132 -3.5.2.6 aztreonam pseudomonas aeruginosa 10.0 10.0 1 PMID:16127048 -3.5.2.6 aztreonam pseudomonas luteola 1.5 1.5 1 PMID:19884377 -3.5.2.6 aztreonam riemerella anatipestifer 3.3 3.3 1 PMID:35580446 -3.5.2.6 aztreonam serratia fonticola 162.0 100.0 2 PMID:17875998;PMID:9300809 -3.5.2.6 aztreonam shouchella clausii 0.3 0.3 1 PMID:17846134 -3.5.2.6 benzyl [[(2r)-2-hydroxy-3-phenylpropanoyl]oxy]carbamate enterobacter cloacae 5.9 5.9 1 PMID:21087009 -3.5.2.6 benzyl [[(2s)-2-hydroxy-2-phenylacetyl]oxy]carbamate enterobacter cloacae 3.5 3.5 1 PMID:21087009 -3.5.2.6 benzyl [[(2s)-2-hydroxy-3-phenylpropanoyl]oxy]carbamate enterobacter cloacae 8.7 8.7 1 PMID:21087009 -3.5.2.6 benzyl [[(2s)-2-hydroxy-4-phenylbutanoyl]oxy]carbamate enterobacter cloacae 1.5 1.5 1 PMID:21087009 -3.5.2.6 benzyl [[(2s)-2-hydroxypropanoyl]oxy]carbamate enterobacter cloacae 1.5 1.5 1 PMID:21087009 -3.5.2.6 benzylpenicillin achromobacter xylosoxidans 0.1 0.1 1 PMID:18362192 -3.5.2.6 benzylpenicillin acinetobacter baumannii 0.2 0.2 1 PMID:16189095 -3.5.2.6 benzylpenicillin acinetobacter bereziniae 11.0 11.0 1 PMID:22508298 -3.5.2.6 benzylpenicillin aeromonas hydrophila 0.03 0.03 1 PMID:18498253 -3.5.2.6 benzylpenicillin aeromonas sobria 1.2 0.8665 2 PMID:8998985;PMID:9182099 -3.5.2.6 benzylpenicillin bacillus cereus 2200.0 1775.0 2 PMID:10209286 -3.5.2.6 benzylpenicillin bacillus licheniformis 2650.0 2650.0 1 PMID:1974463 -3.5.2.6 benzylpenicillin brachyspira pilosicoli 4.9 4.9 1 PMID:18212108 -3.5.2.6 benzylpenicillin burkholderia cenocepacia 130.0 130.0 1 PMID:19075063 -3.5.2.6 benzylpenicillin chryseobacterium indologenes 10.92 10.92 1 PMID:17470648 -3.5.2.6 benzylpenicillin enterobacter cloacae 260.0 139.0 2 PMID:18312599;PMID:8807798 -3.5.2.6 benzylpenicillin escherichia coli 1400.0 51.5 10 PMID:15561863;PMID:16189104;PMID:17207608;PMID:18171085;PMID:7822311;PMID:8056282;PMID:9735103 -3.5.2.6 benzylpenicillin fusobacterium nucleatum 830.0 830.0 2 PMID:16870757 -3.5.2.6 benzylpenicillin klebsiella aerogenes 3.5 3.5 1 PMID:18160520 -3.5.2.6 benzylpenicillin klebsiella pneumoniae 420.0 368.5 2 PMID:15561863;PMID:17467221 -3.5.2.6 benzylpenicillin kluyvera ascorbata 10.0 10.0 1 PMID:17196371 -3.5.2.6 benzylpenicillin moraxella catarrhalis 41.0 40.5 2 PMID:1396750 -3.5.2.6 benzylpenicillin morganella morganii subsp. morganii 0.0074 0.0074 1 PMID:16495258 -3.5.2.6 benzylpenicillin plasmid pgem-t-easy 120.0 102.5 2 PMID:19860471 -3.5.2.6 benzylpenicillin plasmid pqe32chl17 1160.0 1160.0 1 PMID:19177359 -3.5.2.6 benzylpenicillin pseudomonas aeruginosa 650.0 111.5 6 PMID:15155197;PMID:16127048;PMID:18362187;PMID:18559652;PMID:21041509;PMID:21149620 -3.5.2.6 benzylpenicillin pseudomonas fluorescens 34.3 34.3 1 PMID:18312599 -3.5.2.6 benzylpenicillin psychrobacter immobilis 20.0 20.0 1 PMID:18312599 -3.5.2.6 benzylpenicillin serratia fonticola 770.0 770.0 1 PMID:9300809 -3.5.2.6 benzylpenicillin serratia marcescens 650.0 362.5 2 PMID:15788415;PMID:18312599 -3.5.2.6 benzylpenicillin shewanella algae 4.0 4.0 1 PMID:15105119 -3.5.2.6 benzylpenicillin shouchella clausii 97.0 97.0 1 PMID:17846134 -3.5.2.6 benzylpenicillin staphylococcus aureus 135.0 135.0 1 PMID:10209286 -3.5.2.6 benzylpenicillin streptomyces cacaoi 473.0 473.0 1 PMID:6970744 -3.5.2.6 benzylpenicillin yersinia ruckeri 45.0 45.0 1 PMID:16553832 -3.5.2.6 biapenem aeromonas hydrophila 300.0 300.0 2 PMID:15588826;PMID:18498253 -3.5.2.6 biapenem aeromonas sobria 1.5 1.5 1 PMID:8998985 -3.5.2.6 biapenem pseudomonas aeruginosa 15.0 15.0 1 PMID:21149620 -3.5.2.6 biapenem stenotrophomonas maltophilia 134.0 99.0 2 PMID:14573595;PMID:9559809 -3.5.2.6 bocillin-fl mycolicibacterium smegmatis 12.03 7.875 2 PMID:28421415 -3.5.2.6 carbenicillin aeromonas sobria 0.5 0.4665 2 PMID:8998985;PMID:9182099 -3.5.2.6 carbenicillin bacteroides fragilis 260.0 260.0 1 PMID:9126607 -3.5.2.6 carbenicillin brachyspira pilosicoli 1.1 1.1 1 PMID:18212108 -3.5.2.6 carbenicillin chryseobacterium indologenes 16.96 16.96 1 PMID:17470648 -3.5.2.6 carbenicillin enterobacter cloacae 0.004 0.004 1 PMID:18312599 -3.5.2.6 carbenicillin escherichia coli 32.0 32.0 1 PMID:9735103 -3.5.2.6 carbenicillin kluyvera ascorbata 1.0 1.0 1 PMID:17196371 -3.5.2.6 carbenicillin mycolicibacterium smegmatis 10.22 10.22 1 PMID:28421415 -3.5.2.6 carbenicillin pseudomonas aeruginosa 1200.0 650.0 4 PMID:11148033;PMID:15561840;PMID:18559652;PMID:21149620 -3.5.2.6 carbenicillin pseudomonas fluorescens 0.52 0.52 1 PMID:18312599 -3.5.2.6 carbenicillin pseudomonas putida 3.7 3.7 1 PMID:12709317 -3.5.2.6 carbenicillin serratia fonticola 100.0 54.575 2 PMID:21876065;PMID:9300809 -3.5.2.6 cefaclor escherichia coli 38.0 26.5 6 PMID:19228020 -3.5.2.6 cefaclor moraxella catarrhalis 69.0 67.0 2 PMID:1396750 -3.5.2.6 cefaclor stenotrophomonas maltophilia 60.0 51.0 2 PMID:14573595;PMID:9559809 -3.5.2.6 cefadroxil stenotrophomonas maltophilia 23.0 23.0 1 PMID:9559809 -3.5.2.6 cefaloridine escherichia coli 1300.0 1160.0 2 PMID:17207608;PMID:9735103 -3.5.2.6 cefalothin escherichia coli 510.0 510.0 1 PMID:17207608 -3.5.2.6 cefalothin pseudomonas putida 440.0 440.0 1 PMID:18757180 -3.5.2.6 cefalotin acinetobacter baylyi 4.22 4.22 1 PMID:17403709 -3.5.2.6 cefalotin escherichia coli 1190.0 45.0 7 PMID:18281307;PMID:25324420 -3.5.2.6 cefalotin klebsiella pneumoniae 75.0 75.0 1 PMID:25324420 -3.5.2.6 cefamandole mycobacterium tuberculosis 58.3 58.3 1 PMID:17915954 -3.5.2.6 cefamandole serratia fonticola 6110.0 6110.0 1 PMID:9300809 -3.5.2.6 cefamandole staphylococcus aureus 0.35 0.175 4 PMID:1605608 -3.5.2.6 cefazolin aeromonas enteropelogenes 0.55 0.4 2 PMID:20124004 -3.5.2.6 cefazolin chryseobacterium indologenes 0.46 0.46 1 PMID:17470648 -3.5.2.6 cefazolin enterobacter cloacae 3000.0 3000.0 1 PMID:18312599 -3.5.2.6 cefazolin escherichia coli 560.0 442.5 2 PMID:16189104 -3.5.2.6 cefazolin klebsiella aerogenes 2.2 2.2 1 PMID:18160520 -3.5.2.6 cefazolin plasmid pqe32chl17 69.0 69.0 1 PMID:19177359 -3.5.2.6 cefazolin pseudomonas fluorescens 61.0 61.0 1 PMID:18312599 -3.5.2.6 cefazolin psychrobacter immobilis 476.0 476.0 1 PMID:18312599 -3.5.2.6 cefazolin serratia marcescens 1300.0 1300.0 1 PMID:18312599 -3.5.2.6 cefazolin staphylococcus aureus 4.67 2.935 4 PMID:1605608 -3.5.2.6 cefcapene escherichia coli 110.0 110.0 1 PMID:17207608 -3.5.2.6 cefdinir escherichia coli 83.0 83.0 1 PMID:17207608 -3.5.2.6 cefepime aeromonas enteropelogenes 0.0094 0.0094 1 PMID:20124004 -3.5.2.6 cefepime aliivibrio salmonicida 0.58 0.58 1 PMID:25362569 -3.5.2.6 cefepime burkholderia cenocepacia 10.0 10.0 1 PMID:19075063 -3.5.2.6 cefepime enterobacter cloacae 0.1 0.1 1 PMID:16189133 -3.5.2.6 cefepime escherichia coli 34.0 1.0 3 PMID:10438473;PMID:15215122;PMID:18031291 -3.5.2.6 cefepime klebsiella aerogenes 2.4 2.4 1 PMID:18160520 -3.5.2.6 cefepime klebsiella pneumoniae 30.0 16.5 2 PMID:18316524;PMID:21911565 -3.5.2.6 cefepime morganella morganii subsp. morganii 0.008 0.008 1 PMID:16495258 -3.5.2.6 cefepime pseudomonas aeruginosa 119.0 39.0 10 PMID:15561840;PMID:16127048;PMID:18362187;PMID:18559652;PMID:18644957;PMID:20974864;PMID:21041509 -3.5.2.6 cefepime pseudomonas putida 15.0 11.5 2 PMID:12709317;PMID:18757180 -3.5.2.6 cefepime riemerella anatipestifer 0.21 0.21 1 PMID:35580446 -3.5.2.6 cefepime serratia fonticola 225.0 112.82 2 PMID:21876065;PMID:9300809 -3.5.2.6 cefepime shigella sonnei 67.7 67.7 1 PMID:18955524 -3.5.2.6 cefepime shouchella clausii 40.0 40.0 1 PMID:17846134 -3.5.2.6 cefepime stenotrophomonas maltophilia 0.333 0.333 1 PMID:9559809 -3.5.2.6 cefmetazole stenotrophomonas maltophilia 4.7 4.7 1 PMID:9559809 -3.5.2.6 cefoperazone klebsiella pneumoniae 229.5 229.5 1 PMID:29228168 -3.5.2.6 cefoperazone kluyvera ascorbata 0.22 0.22 1 PMID:17196371 -3.5.2.6 cefoperazone serratia fonticola 70.0 70.0 1 PMID:9300809 -3.5.2.6 cefoperrazone escherichia coli 804.07 804.07 1 PMID:37170014 -3.5.2.6 cefotaxime aeromonas enteropelogenes 0.015 0.015 1 PMID:20124004 -3.5.2.6 cefotaxime aeromonas hydrophila 0.0002 0.0002 1 PMID:18498253 -3.5.2.6 cefotaxime bacteroides fragilis 25.0 25.0 1 PMID:9126607 -3.5.2.6 cefotaxime burkholderia cenocepacia 20.0 20.0 1 PMID:19075063 -3.5.2.6 cefotaxime chryseobacterium indologenes 1.53 1.53 1 PMID:17470648 -3.5.2.6 cefotaxime citrobacter freundii 2181.0 2181.0 1 PMID:18765691 -3.5.2.6 cefotaxime elizabethkingia meningoseptica 39.0 39.0 1 * -3.5.2.6 cefotaxime enterobacter cloacae 286.0 35.6 6 PMID:14992604;PMID:16189133;PMID:8807798 -3.5.2.6 cefotaxime escherichia coli 1400.0 4.0 16 PMID:10438473;PMID:15215122;PMID:15561863;PMID:16189104;PMID:16251324;PMID:17207608;PMID:18031291;PMID:18281307;PMID:19001118;PMID:35175332 -3.5.2.6 cefotaxime janthinobacterium lividum 80.0 80.0 1 PMID:15561856 -3.5.2.6 cefotaxime klebsiella aerogenes 0.07 0.07 1 PMID:18160520 -3.5.2.6 cefotaxime klebsiella pneumoniae 120.0 13.5 4 PMID:15561863;PMID:17467221;PMID:18316524;PMID:21911565 -3.5.2.6 cefotaxime kluyvera ascorbata 3.3 3.3 1 PMID:17196371 -3.5.2.6 cefotaxime metapseudomonas otitidis 56.0 56.0 1 PMID:25512428 -3.5.2.6 cefotaxime morganella morganii subsp. morganii 0.09 0.051000000000000004 4 PMID:16495258 -3.5.2.6 cefotaxime mycolicibacterium smegmatis 1.572 1.572 1 PMID:28421415 -3.5.2.6 cefotaxime pectobacterium carotovorum 250.0 250.0 1 PMID:18443127 -3.5.2.6 cefotaxime plasmid pbc 142.0 142.0 1 PMID:20421396 -3.5.2.6 cefotaxime plasmid pqe32chl17 0.74 0.74 1 PMID:19177359 -3.5.2.6 cefotaxime providencia stuartii 1.5 1.5 1 PMID:15328132 -3.5.2.6 cefotaxime pseudomonas aeruginosa 612.0 48.65 10 PMID:12709317;PMID:15561840;PMID:16127048;PMID:18362187;PMID:18559652;PMID:18644957;PMID:20974864;PMID:21041509 -3.5.2.6 cefotaxime pseudomonas luteola 452.0 452.0 1 PMID:19884377 -3.5.2.6 cefotaxime pseudomonas putida 398.0 227.0 2 PMID:12709317;PMID:18559652;PMID:18757180 -3.5.2.6 cefotaxime riemerella anatipestifer 34.0 34.0 1 PMID:35580446 -3.5.2.6 cefotaxime serratia fonticola 920.0 464.15 2 PMID:17875998;PMID:9300809 -3.5.2.6 cefotaxime shigella sonnei 197.0 197.0 1 PMID:18955524 -3.5.2.6 cefotaxime shouchella clausii 22.0 22.0 1 PMID:17846134 -3.5.2.6 cefotaxime stenotrophomonas maltophilia 140.0 140.0 1 PMID:9559809 -3.5.2.6 cefotaxime yersinia ruckeri 0.3 0.3 1 PMID:16553832 -3.5.2.6 cefotetan enterobacter cloacae 5.0 5.0 1 PMID:8807798 -3.5.2.6 cefotiam serratia fonticola 945.0 945.0 1 PMID:9300809 -3.5.2.6 cefoxitin achromobacter sp. sallbros1 0.3 0.3 1 PMID:22290947 -3.5.2.6 cefoxitin aeromonas enteropelogenes 0.88 0.88 1 PMID:20124004 -3.5.2.6 cefoxitin aliivibrio salmonicida 0.27 0.27 1 PMID:25362569 -3.5.2.6 cefoxitin bacteroides fragilis 150.0 150.0 1 PMID:9126607 -3.5.2.6 cefoxitin citrobacter freundii 1178.0 1178.0 1 PMID:18765691 -3.5.2.6 cefoxitin elizabethkingia meningoseptica 6.0 6.0 1 * -3.5.2.6 cefoxitin enterobacter cloacae 5.0 5.0 1 PMID:8807798 -3.5.2.6 cefoxitin escherichia coli 18.0 0.64 13 PMID:15215122;PMID:16189104;PMID:19001118;PMID:25324420 -3.5.2.6 cefoxitin klebsiella pneumoniae 10.0 9.8 2 PMID:17467221;PMID:25324420 -3.5.2.6 cefoxitin kluyvera ascorbata 0.00043 0.00043 1 PMID:17196371 -3.5.2.6 cefoxitin morganella morganii subsp. morganii 0.038 0.038 1 PMID:16495258 -3.5.2.6 cefoxitin mycobacterium tuberculosis 1.1 0.9500000000000001 2 PMID:16870770;PMID:17915954 -3.5.2.6 cefoxitin pectobacterium carotovorum 7.0 7.0 1 PMID:18443127 -3.5.2.6 cefoxitin pseudomonas aeruginosa 35.0 8.3 5 PMID:15561840;PMID:18362187;PMID:18559652;PMID:20974864;PMID:21041509 -3.5.2.6 cefoxitin pseudomonas putida 7.0 7.0 1 PMID:18757180 -3.5.2.6 cefoxitin serratia fonticola 4.2 2.116 2 PMID:17875998;PMID:21876065 -3.5.2.6 cefoxitin shouchella clausii 0.01 0.01 1 PMID:17846134 -3.5.2.6 cefoxitin stenotrophomonas maltophilia 2.2 2.05 2 PMID:14573595;PMID:9559809 -3.5.2.6 cefoxitin yersinia ruckeri 0.3 0.3 1 PMID:16553832 -3.5.2.6 cefpirome aeromonas enteropelogenes 23.0 23.0 1 PMID:20124004 -3.5.2.6 cefpirome escherichia coli 1.5 1.5 1 PMID:15215122 -3.5.2.6 cefpirome pseudomonas aeruginosa 102.0 102.0 1 PMID:18362187 -3.5.2.6 cefpirome serratia fonticola 745.0 745.0 1 PMID:9300809 -3.5.2.6 cefpirome shewanella algae 0.1 0.1 1 PMID:15105119 -3.5.2.6 cefpirome shouchella clausii 95.0 95.0 1 PMID:17846134 -3.5.2.6 cefprozil stenotrophomonas maltophilia 15.0 15.0 1 PMID:9559809 -3.5.2.6 cefsulodin stenotrophomonas maltophilia 0.0833 0.0833 1 PMID:9559809 -3.5.2.6 cefsulodine pseudomonas aeruginosa 25.0 25.0 1 PMID:16127048 -3.5.2.6 ceftaxidime klebsiella pneumoniae 0.3 0.3 1 PMID:17467221 -3.5.2.6 ceftazidime achromobacter sp. sallbros1 0.07 0.07 1 PMID:22290947 -3.5.2.6 ceftazidime aeromonas enteropelogenes 0.11 0.11 1 PMID:20124004 -3.5.2.6 ceftazidime aliivibrio salmonicida 0.09 0.09 1 PMID:25362569 -3.5.2.6 ceftazidime bacteroides fragilis 140.0 140.0 1 PMID:9126607 -3.5.2.6 ceftazidime burkholderia cenocepacia 1.5 1.5 1 PMID:19075063 -3.5.2.6 ceftazidime citrobacter freundii 118.0 118.0 1 PMID:18765691 -3.5.2.6 ceftazidime enterobacter cloacae 4.67 2.435 2 PMID:16189133;PMID:8807798 -3.5.2.6 ceftazidime escherichia coli 33.0 6.5 12 PMID:10438473;PMID:15215122;PMID:15561863;PMID:16251324;PMID:19001118;PMID:25324420 -3.5.2.6 ceftazidime janthinobacterium lividum 20.0 20.0 1 PMID:15561856 -3.5.2.6 ceftazidime klebsiella aerogenes 8.3 8.3 1 PMID:18160520 -3.5.2.6 ceftazidime klebsiella pneumoniae 24.0 12.0 4 PMID:15561863;PMID:18316524;PMID:21911565;PMID:25324420 -3.5.2.6 ceftazidime morganella morganii subsp. morganii 0.04 0.04 1 PMID:16495258 -3.5.2.6 ceftazidime mycobacterium tuberculosis 0.2 0.1165 2 PMID:16870770;PMID:17915954 -3.5.2.6 ceftazidime pectobacterium carotovorum 160.0 160.0 1 PMID:18443127 -3.5.2.6 ceftazidime providencia stuartii 12.0 12.0 1 PMID:15328132 -3.5.2.6 ceftazidime pseudomonas aeruginosa 42.0 10.0 9 PMID:15561840;PMID:18362187;PMID:18559652;PMID:18644957;PMID:20974864;PMID:21041509 -3.5.2.6 ceftazidime pseudomonas luteola 1.3 1.3 1 PMID:19884377 -3.5.2.6 ceftazidime pseudomonas putida 12.0 9.35 2 PMID:12709317;PMID:18757180 -3.5.2.6 ceftazidime riemerella anatipestifer 0.34 0.34 1 PMID:35580446 -3.5.2.6 ceftazidime serratia fonticola 30.0 16.05 2 PMID:17875998;PMID:9300809 -3.5.2.6 ceftazidime shewanella algae 2.0 2.0 1 PMID:15105119 -3.5.2.6 ceftazidime shouchella clausii 3.3 3.3 1 PMID:17846134 -3.5.2.6 ceftazidime yersinia ruckeri 1.0 1.0 1 PMID:16553832 -3.5.2.6 ceftizoxime stenotrophomonas maltophilia 2.7 2.7 1 PMID:9559809 -3.5.2.6 ceftriaxone aeromonas enteropelogenes 0.042 0.042 1 PMID:20124004 -3.5.2.6 ceftriaxone mycobacterium tuberculosis 0.82 0.82 1 PMID:17915954 -3.5.2.6 ceftriaxone mycolicibacterium smegmatis 1.825 1.825 1 PMID:28421415 -3.5.2.6 ceftriaxone pectobacterium carotovorum 13.0 13.0 1 PMID:18443127 -3.5.2.6 ceftriaxone pseudomonas aeruginosa 25.0 25.0 1 PMID:16127048 -3.5.2.6 ceftriaxone shouchella clausii 30.0 30.0 1 PMID:17846134 -3.5.2.6 ceftriazone serratia fonticola 620.0 620.0 1 PMID:9300809 -3.5.2.6 cefuroxime achromobacter sp. sallbros1 0.1 0.1 1 PMID:22290947 -3.5.2.6 cefuroxime aeromonas enteropelogenes 0.042 0.042 1 PMID:20124004 -3.5.2.6 cefuroxime aliivibrio salmonicida 11.0 11.0 1 PMID:25362569 -3.5.2.6 cefuroxime bacillus licheniformis 0.02 0.02 1 PMID:21705325 -3.5.2.6 cefuroxime burkholderia cenocepacia 170.0 170.0 1 PMID:19075063 -3.5.2.6 cefuroxime enterobacter cloacae 74.8 0.28 3 PMID:14992604 -3.5.2.6 cefuroxime escherichia coli 190.0 0.56 6 PMID:15561863;PMID:16189104;PMID:7822311 -3.5.2.6 cefuroxime janthinobacterium lividum 140.0 140.0 1 PMID:15561856 -3.5.2.6 cefuroxime klebsiella pneumoniae 21.0 7.0 3 PMID:15561863;PMID:18316524;PMID:21911565 -3.5.2.6 cefuroxime kluyvera ascorbata 2.5 2.5 1 PMID:17196371 -3.5.2.6 cefuroxime moraxella catarrhalis 4.8 4.449999999999999 2 PMID:1396750 -3.5.2.6 cefuroxime mycobacterium tuberculosis 8.17 8.17 1 PMID:17915954 -3.5.2.6 cefuroxime pectobacterium carotovorum 400.0 400.0 1 PMID:18443127 -3.5.2.6 cefuroxime pseudomonas aeruginosa 283.0 27.0 11 PMID:15561840;PMID:16127048;PMID:18362187;PMID:18559652;PMID:18644957;PMID:20974864;PMID:21041509;PMID:21149620 -3.5.2.6 cefuroxime pseudomonas luteola 286.0 286.0 1 PMID:19884377 -3.5.2.6 cefuroxime pseudomonas putida 61.0 61.0 1 PMID:12709317 -3.5.2.6 cefuroxime riemerella anatipestifer 129.0 129.0 1 PMID:35580446 -3.5.2.6 cefuroxime serratia fonticola 540.0 540.0 1 PMID:9300809 -3.5.2.6 cefuroxime shouchella clausii 15.0 15.0 1 PMID:17846134 -3.5.2.6 cefuroxime staphylococcus aureus 0.00833 0.00833 1 PMID:1605608 -3.5.2.6 cefuroxime stenotrophomonas maltophilia 53.0 53.0 1 PMID:9559809 -3.5.2.6 cefuroxime yersinia ruckeri 1.0 1.0 1 PMID:16553832 -3.5.2.6 centa fusobacterium nucleatum 0.42 0.42 1 PMID:16870757 -3.5.2.6 centa mycobacterium tuberculosis 29.5 29.5 1 PMID:17915954 -3.5.2.6 cephalexin aeromonas enteropelogenes 160.0 160.0 1 PMID:20124004 -3.5.2.6 cephalexin bacillus anthracis 4.83 4.83 1 PMID:21369909 -3.5.2.6 cephalexin enterobacter cloacae 72.0 72.0 1 PMID:18312599 -3.5.2.6 cephalexin escherichia coli 115.0 70.0 4 PMID:16189104 -3.5.2.6 cephalexin mycolicibacterium smegmatis 0.079 0.079 1 PMID:28421415 -3.5.2.6 cephalexin plasmid pbg66 13.0 13.0 1 PMID:19812041 -3.5.2.6 cephalexin pseudomonas fluorescens 31.0 31.0 1 PMID:18312599 -3.5.2.6 cephalexin psychrobacter immobilis 26.0 26.0 1 PMID:18312599 -3.5.2.6 cephalexin serratia marcescens 80.0 80.0 1 PMID:18312599 -3.5.2.6 cephaloridin yersinia ruckeri 120.0 120.0 1 PMID:16553832 -3.5.2.6 cephaloridine acinetobacter baumannii 0.05 0.05 1 PMID:16189095 -3.5.2.6 cephaloridine acinetobacter sp. 16.0 16.0 1 PMID:20086146 -3.5.2.6 cephaloridine aeromonas hydrophila 0.006 0.006 1 PMID:18498253 -3.5.2.6 cephaloridine bacteroides fragilis 20.0 20.0 1 PMID:9126607 -3.5.2.6 cephaloridine burkholderia pseudomallei 13.0 13.0 1 PMID:15793160 -3.5.2.6 cephaloridine citrobacter freundii 686.0 686.0 1 PMID:18765691 -3.5.2.6 cephaloridine elizabethkingia meningoseptica 14.0 14.0 1 * -3.5.2.6 cephaloridine escherichia coli 780.0 235.0 10 PMID:10438473;PMID:15215122;PMID:16189104;PMID:16251324;PMID:19001118;PMID:7822311;PMID:8056282 -3.5.2.6 cephaloridine klebsiella pneumoniae 190.0 190.0 1 PMID:17467221 -3.5.2.6 cephaloridine moraxella catarrhalis 5.6 5.199999999999999 2 PMID:1396750 -3.5.2.6 cephaloridine plasmid pgem-t-easy 70.0 52.5 2 PMID:19860471 -3.5.2.6 cephaloridine plasmid rgn238 16.0 16.0 1 PMID:20086146 -3.5.2.6 cephaloridine providencia stuartii 15.0 15.0 1 PMID:15328132 -3.5.2.6 cephaloridine pseudomonas aeruginosa 180.0 105.0 2 PMID:16127048;PMID:18559652 -3.5.2.6 cephaloridine serratia fonticola 2530.0 2530.0 1 PMID:9300809 -3.5.2.6 cephaloridine serratia marcescens 90.0 90.0 1 PMID:15788415 -3.5.2.6 cephaloridine shewanella algae 10.0 10.0 1 PMID:15105119 -3.5.2.6 cephaloridine shouchella clausii 115.0 115.0 1 PMID:17846134 -3.5.2.6 cephaloridine staphylococcus aureus 6.65 3.775 4 PMID:1605608 -3.5.2.6 cephaloridine stenotrophomonas maltophilia 67.0 67.0 1 PMID:9559809 -3.5.2.6 cephalosporin c bacillus cereus 0.2 0.2 1 * -3.5.2.6 cephalosporin c escherichia coli 33.0 33.0 1 PMID:10438473 -3.5.2.6 cephalosporin c moraxella catarrhalis 5.0 4.85 2 PMID:1396750 -3.5.2.6 cephalosporin c mycobacterium tuberculosis 17.83 17.83 1 PMID:17915954 -3.5.2.6 cephalosporin c stenotrophomonas maltophilia 280.0 280.0 1 PMID:9559809 -3.5.2.6 cephalothin achromobacter xylosoxidans 0.5 0.5 1 PMID:18362192 -3.5.2.6 cephalothin acinetobacter baumannii 19.78 19.01 3 PMID:16189095;PMID:37095236 -3.5.2.6 cephalothin acinetobacter bereziniae 0.2 0.2 1 PMID:22508298 -3.5.2.6 cephalothin aeromonas enteropelogenes 470.0 470.0 1 PMID:20124004 -3.5.2.6 cephalothin burkholderia cenocepacia 300.0 300.0 1 PMID:19075063 -3.5.2.6 cephalothin burkholderia pseudomallei 0.28 0.28 1 PMID:15793160 -3.5.2.6 cephalothin enterobacter cloacae 2820.0 690.0 5 PMID:14992604;PMID:8807798 -3.5.2.6 cephalothin escherichia coli 922.14 345.0 12 PMID:10438473;PMID:15561863;PMID:16189104;PMID:18031291;PMID:19001118;PMID:35175332;PMID:37170014;PMID:8056282 -3.5.2.6 cephalothin fusobacterium nucleatum 4.1 4.1 2 PMID:16870757 -3.5.2.6 cephalothin klebsiella pneumoniae 530.0 49.7 5 PMID:15561863;PMID:17467221;PMID:18316524;PMID:19477418;PMID:29228168 -3.5.2.6 cephalothin kluyvera ascorbata 56.0 56.0 1 PMID:17196371 -3.5.2.6 cephalothin metapseudomonas otitidis 60.0 60.0 1 PMID:25512428 -3.5.2.6 cephalothin moraxella catarrhalis 4.9 4.75 2 PMID:1396750 -3.5.2.6 cephalothin morganella morganii subsp. morganii 140.0 14.0 6 PMID:16495258 -3.5.2.6 cephalothin mycobacterium tuberculosis 12.1 12.1 1 PMID:16870770 -3.5.2.6 cephalothin mycolicibacterium smegmatis 1.031 1.031 1 PMID:28421415 -3.5.2.6 cephalothin pectobacterium carotovorum 240.0 240.0 1 PMID:18443127 -3.5.2.6 cephalothin plasmid pbc 44.0 44.0 1 PMID:20421396 -3.5.2.6 cephalothin plasmid pbg66 146.0 146.0 1 PMID:19812041 -3.5.2.6 cephalothin plasmid pgem-t-easy 2.5 2.25 2 PMID:19860471 -3.5.2.6 cephalothin plasmid pqe32chl17 77.0 77.0 1 PMID:19177359 -3.5.2.6 cephalothin pseudomonas aeruginosa 656.0 314.5 8 PMID:15561840;PMID:16127048;PMID:18362187;PMID:18559652;PMID:18644957 -3.5.2.6 cephalothin pseudomonas luteola 543.0 543.0 1 PMID:19884377 -3.5.2.6 cephalothin pseudomonas putida 118.0 118.0 1 PMID:12709317 -3.5.2.6 cephalothin riemerella anatipestifer 200.0 200.0 1 PMID:35580446 -3.5.2.6 cephalothin serratia fonticola 7150.0 3715.0 2 PMID:17875998;PMID:9300809 -3.5.2.6 cephalothin shewanella algae 0.6 0.6 1 PMID:15105119 -3.5.2.6 cephalothin shigella sonnei 185.0 185.0 1 PMID:18955524 -3.5.2.6 cephalothin shouchella clausii 22.0 22.0 1 PMID:17846134 -3.5.2.6 cephalothin staphylococcus aureus 0.1 0.05835 4 PMID:1605608 -3.5.2.6 cephalothin stenotrophomonas maltophilia 82.0 73.5 2 PMID:14573595;PMID:9559809 -3.5.2.6 cephalothin synthetic construct 14.0 12.0 2 PMID:19351161 -3.5.2.6 cephalothin yersinia ruckeri 400.0 400.0 1 PMID:16553832 -3.5.2.6 cephalotin escherichia coli 153.0 139.0 2 PMID:16251324;PMID:18171085 -3.5.2.6 cephalotin klebsiella pneumoniae 1.0 1.0 1 PMID:21911565 -3.5.2.6 cephalotin mycobacterium tuberculosis 8.17 8.17 1 PMID:17915954 -3.5.2.6 cephalotin pseudomonas aeruginosa 500.0 12.7 4 PMID:15155197;PMID:20974864;PMID:21041509;PMID:21149620 -3.5.2.6 cephapirin staphylococcus aureus 1.82 0.7735 4 PMID:1605608 -3.5.2.6 cephradine stenotrophomonas maltophilia 16.0 16.0 1 PMID:9559809 -3.5.2.6 clavulanic acid stenotrophomonas maltophilia 11.0 11.0 1 PMID:9559809 -3.5.2.6 cloxacillin burkholderia pseudomallei 0.51 0.51 1 PMID:15793160 -3.5.2.6 cloxacillin enterobacter cloacae 0.004 0.004 1 PMID:18312599 -3.5.2.6 cloxacillin moraxella catarrhalis 8.6 6.8 2 PMID:1396750 -3.5.2.6 cloxacillin plasmid pgem-t-easy 500.0 310.0 2 PMID:19860471 -3.5.2.6 cloxacillin pseudomonas aeruginosa 2500.0 2500.0 1 PMID:18559652 -3.5.2.6 cloxacillin pseudomonas fluorescens 0.42 0.42 1 PMID:18312599 -3.5.2.6 cloxacillin serratia fonticola 90.0 90.0 1 PMID:9300809 -3.5.2.6 cloxacillin shewanella algae 0.5 0.5 1 PMID:15105119 -3.5.2.6 doripenem escherichia coli 1032.0 267.0 7 PMID:17207608;PMID:25324420 -3.5.2.6 doripenem klebsiella pneumoniae 226.0 226.0 1 PMID:25324420 -3.5.2.6 doripenem metapseudomonas otitidis 51.0 51.0 1 PMID:25512428 -3.5.2.6 doripenem mycobacterium tuberculosis 0.00033 0.00033 1 PMID:24846409 -3.5.2.6 ertapenem achromobacter sp. sallbros1 0.4 0.4 1 PMID:22290947 -3.5.2.6 ertapenem aliivibrio salmonicida 4.3 4.15 2 PMID:25362569 -3.5.2.6 ertapenem klebsiella pneumoniae 0.13 0.13 1 PMID:19477418 -3.5.2.6 ertapenem metapseudomonas otitidis 69.0 69.0 1 PMID:25512428 -3.5.2.6 ertapenem mycobacterium tuberculosis 0.00033 0.00033 1 PMID:24846409 -3.5.2.6 ertapenem pseudomonas aeruginosa 8.0 1.8 3 PMID:18559652;PMID:20974864;PMID:21041509 -3.5.2.6 ertapenem pseudomonas putida 25.0 25.0 1 PMID:18757180 -3.5.2.6 faropenem klebsiella pneumoniae 0.038 0.038 1 PMID:19477418 -3.5.2.6 faropenem pectobacterium carotovorum 5.0 5.0 1 PMID:18443127 -3.5.2.6 imipenem achromobacter sp. sallbros1 1.7 1.7 1 PMID:22290947 -3.5.2.6 imipenem acinetobacter baumannii 1.18 0.85 3 PMID:15105119;PMID:15155197;PMID:16189095;PMID:19075063;PMID:37095236 -3.5.2.6 imipenem acinetobacter bereziniae 0.09 0.09 1 PMID:22508298 -3.5.2.6 imipenem aeromonas hydrophila 1200.0 210.0 5 PMID:15588826;PMID:17307979;PMID:18498253 -3.5.2.6 imipenem aeromonas sobria 160.0 115.5 2 PMID:8998985;PMID:9182099 -3.5.2.6 imipenem aeromonas veronii bv. sobria 295.0 295.0 1 PMID:18528987 -3.5.2.6 imipenem aliivibrio salmonicida 8.0 8.0 1 PMID:25362569 -3.5.2.6 imipenem bacteroides fragilis 100.0 100.0 1 PMID:18559652;PMID:9126607 -3.5.2.6 imipenem burkholderia cenocepacia 0.1 0.1 1 PMID:15105119;PMID:15155197;PMID:16189095;PMID:19075063 -3.5.2.6 imipenem chryseobacterium indologenes 7.28 7.28 1 PMID:17470648 -3.5.2.6 imipenem citrobacter freundii 15.0 15.0 1 PMID:18765691 -3.5.2.6 imipenem elizabethkingia meningoseptica 350.0 350.0 1 * -3.5.2.6 imipenem enterobacter cloacae 1040.0 521.75 2 PMID:16189133;PMID:8807798 -3.5.2.6 imipenem escherichia coli 757.0 45.0 21 PMID:16189104;PMID:16251324;PMID:17207608;PMID:19001118;PMID:19228020;PMID:25324420;PMID:37170014 -3.5.2.6 imipenem janthinobacterium lividum 120.0 120.0 1 PMID:15561856 -3.5.2.6 imipenem klebsiella pneumoniae 600.0 3.0 4 PMID:17467221;PMID:17944487;PMID:19477418;PMID:25324420 -3.5.2.6 imipenem kluyvera ascorbata 0.00024 0.00024 1 PMID:17196371 -3.5.2.6 imipenem metapseudomonas otitidis 312.0 312.0 1 PMID:25512428 -3.5.2.6 imipenem morganella morganii subsp. morganii 0.11 0.07 6 PMID:16495258 -3.5.2.6 imipenem mycobacterium tuberculosis 0.167 0.167 1 PMID:17915954 -3.5.2.6 imipenem plasmid pbc 19.0 19.0 1 PMID:20421396 -3.5.2.6 imipenem pseudomonas aeruginosa 120.0 27.0 11 PMID:15105119;PMID:15155197;PMID:15561840;PMID:16189095;PMID:18362187;PMID:18559652;PMID:18644957;PMID:19075063;PMID:20974864;PMID:21041509;PMID:21149620;PMID:9126607 -3.5.2.6 imipenem pseudomonas putida 240.0 227.0 2 PMID:12709317;PMID:18757180 -3.5.2.6 imipenem serratia fonticola 54.0 52.5 2 PMID:17875998;PMID:21876065 -3.5.2.6 imipenem serratia marcescens 123.3 123.3 1 PMID:15788415 -3.5.2.6 imipenem shewanella algae 0.1 0.1 1 PMID:15105119;PMID:15155197;PMID:16189095;PMID:19075063 -3.5.2.6 imipenem shouchella clausii 0.06 0.06 1 PMID:17846134 -3.5.2.6 imipenem stenotrophomonas maltophilia 370.0 370.0 1 PMID:14573595 -3.5.2.6 loracarbef moraxella catarrhalis 95.0 87.0 2 PMID:1396750 -3.5.2.6 mecillinam moraxella catarrhalis 31.0 30.0 2 PMID:1396750 -3.5.2.6 meropenem achromobacter sp. sallbros1 1.4 1.4 1 PMID:22290947 -3.5.2.6 meropenem acinetobacter baumannii 0.06 0.06 1 PMID:16189095 -3.5.2.6 meropenem acinetobacter bereziniae 0.01 0.01 1 PMID:22508298 -3.5.2.6 meropenem aeromonas sobria 1100.0 660.0 2 PMID:8998985;PMID:9182099 -3.5.2.6 meropenem aliivibrio salmonicida 13.0 13.0 1 PMID:25362569 -3.5.2.6 meropenem burkholderia cenocepacia 1.0 1.0 1 PMID:19075063 -3.5.2.6 meropenem chryseobacterium indologenes 4.13 4.13 1 PMID:17470648 -3.5.2.6 meropenem citrobacter freundii 0.4 0.4 1 PMID:18765691 -3.5.2.6 meropenem enterobacter cloacae 12.0 7.2 2 PMID:16189133;PMID:8807798 -3.5.2.6 meropenem escherichia coli 583.0 216.0 8 PMID:16251324;PMID:17207608;PMID:25324420 -3.5.2.6 meropenem janthinobacterium lividum 200.0 200.0 1 PMID:15561856 -3.5.2.6 meropenem klebsiella pneumoniae 301.0 150.535 2 PMID:19477418;PMID:25324420 -3.5.2.6 meropenem metapseudomonas otitidis 220.0 220.0 1 PMID:25512428 -3.5.2.6 meropenem mycobacterium tuberculosis 0.9 0.0013 3 PMID:16870770;PMID:17915954;PMID:24846409 -3.5.2.6 meropenem pectobacterium carotovorum 1.0 1.0 1 PMID:18443127 -3.5.2.6 meropenem pseudomonas aeruginosa 42.0 8.0 10 PMID:15561840;PMID:18362187;PMID:18559652;PMID:18644957;PMID:20974864;PMID:21041509;PMID:21149620 -3.5.2.6 meropenem pseudomonas putida 40.0 24.75 2 PMID:12709317;PMID:18757180 -3.5.2.6 meropenem serratia fonticola 109.0 57.75 2 PMID:17875998;PMID:21876065 -3.5.2.6 meropenem shewanella algae 0.05 0.05 1 PMID:15105119 -3.5.2.6 meropenem stenotrophomonas maltophilia 157.0 157.0 1 PMID:14573595 -3.5.2.6 methicillin bacillus cereus 145.0 145.0 1 PMID:10209286 -3.5.2.6 methicillin bacteroides fragilis 350.0 350.0 1 PMID:9126607 -3.5.2.6 methicillin moraxella catarrhalis 190.0 179.0 2 PMID:1396750 -3.5.2.6 mezlocillin serratia fonticola 255.0 255.0 1 PMID:9300809 -3.5.2.6 moxalactam citrobacter freundii 2794.0 2794.0 1 PMID:18765691 -3.5.2.6 moxalactam enterobacter cloacae 8.6 8.6 1 PMID:8807798 -3.5.2.6 moxalactam pseudomonas aeruginosa 230.0 122.0 2 PMID:15561840;PMID:18559652 -3.5.2.6 moxalactam serratia fonticola 0.017 0.017 1 PMID:21876065 -3.5.2.6 moxalactam shouchella clausii 0.01 0.01 1 PMID:17846134 -3.5.2.6 moxalactam stenotrophomonas maltophilia 0.15 0.15 1 PMID:9559809 -3.5.2.6 nitrocefin acinetobacter baumannii 212.47 186.99 3 PMID:16189095;PMID:37095236 -3.5.2.6 nitrocefin acinetobacter sp. 96.0 96.0 1 PMID:20086146 -3.5.2.6 nitrocefin aeromonas hydrophila 0.008 0.008 1 PMID:18498253 -3.5.2.6 nitrocefin aeromonas sobria 0.0667 0.0667 1 PMID:9182099 -3.5.2.6 nitrocefin aliivibrio salmonicida 6.3 6.3 1 PMID:25362569 -3.5.2.6 nitrocefin bacillus cereus 34.0 34.0 1 * -3.5.2.6 nitrocefin bacillus licheniformis 1090.0 1090.0 1 PMID:1974463 -3.5.2.6 nitrocefin bacteroides fragilis 225.0 212.5 2 PMID:9126607;PMID:9712862 -3.5.2.6 nitrocefin burkholderia pseudomallei 63.0 63.0 1 PMID:15793160 -3.5.2.6 nitrocefin chryseobacterium indologenes 4.4 4.4 1 PMID:17470648 -3.5.2.6 nitrocefin elizabethkingia meningoseptica 17.0 17.0 1 * -3.5.2.6 nitrocefin enterobacter cloacae 780.0 780.0 1 PMID:18312599 -3.5.2.6 nitrocefin escherichia coli 2220.0 49.0 17 PMID:16189104;PMID:16251324;PMID:17207608;PMID:19228020;PMID:25324420;PMID:35175332;PMID:9735103 -3.5.2.6 nitrocefin klebsiella aerogenes 7.4 7.4 1 PMID:18160520 -3.5.2.6 nitrocefin klebsiella pneumoniae 940.0 68.5 4 PMID:19477418;PMID:21911565;PMID:25324420;PMID:29228168 -3.5.2.6 nitrocefin kluyvera ascorbata 29.0 29.0 1 PMID:17196371 -3.5.2.6 nitrocefin moraxella catarrhalis 233.0 192.0 2 PMID:1396750 -3.5.2.6 nitrocefin morganella morganii subsp. morganii 93.0 93.0 1 PMID:16495258 -3.5.2.6 nitrocefin mycobacterium tuberculosis 111.3 111.3 1 PMID:17915954 -3.5.2.6 nitrocefin mycolicibacterium smegmatis 0.014 0.014 1 PMID:28421415 -3.5.2.6 nitrocefin plasmid pbc 52.0 52.0 1 PMID:20421396 -3.5.2.6 nitrocefin plasmid pgem-t-easy 1700.0 1500.0 2 PMID:19860471 -3.5.2.6 nitrocefin plasmid rgn238 96.0 96.0 1 PMID:20086146 -3.5.2.6 nitrocefin providencia stuartii 5.0 5.0 1 PMID:15328132 -3.5.2.6 nitrocefin pseudomonas aeruginosa 1500.0 114.5 6 PMID:15155197;PMID:15561840;PMID:18362187;PMID:18559652;PMID:21041509;PMID:21149620 -3.5.2.6 nitrocefin pseudomonas fluorescens 550.0 550.0 1 PMID:18312599 -3.5.2.6 nitrocefin pseudomonas putida 570.0 450.0 2 PMID:12709317;PMID:18757180 -3.5.2.6 nitrocefin psychrobacter immobilis 1410.0 1408.5 2 PMID:18312599;PMID:9063463 -3.5.2.6 nitrocefin riemerella anatipestifer 6.0 6.0 1 PMID:35580446 -3.5.2.6 nitrocefin serratia fonticola 0.06 0.06 1 PMID:21876065 -3.5.2.6 nitrocefin serratia marcescens 1240.0 500.85 4 PMID:15788415;PMID:18312599;PMID:21928807 -3.5.2.6 nitrocefin shigella sonnei 252.0 252.0 1 PMID:18955524 -3.5.2.6 nitrocefin staphylococcus aureus 25.6 19.85 4 PMID:1605608 -3.5.2.6 nitrocefin stenotrophomonas maltophilia 63.0 26.0 11 PMID:14573595;PMID:15659541;PMID:18831550;PMID:9559809 -3.5.2.6 nitrocefin synthetic construct 237.0 187.0 2 PMID:19351161 -3.5.2.6 oxacillin acinetobacter baumannii 0.2 0.2 1 PMID:16189095 -3.5.2.6 oxacillin acinetobacter bereziniae 4.2 4.2 1 PMID:22508298 -3.5.2.6 oxacillin acinetobacter sp. 577.0 577.0 1 PMID:20086146 -3.5.2.6 oxacillin bacillus cereus 261.0 261.0 1 PMID:10209286 -3.5.2.6 oxacillin brachyspira pilosicoli 113.0 113.0 1 PMID:18212108 -3.5.2.6 oxacillin burkholderia pseudomallei 1.23 1.23 1 PMID:15793160 -3.5.2.6 oxacillin enterobacter cloacae 0.008 0.008 1 PMID:18312599 -3.5.2.6 oxacillin escherichia coli 0.18 0.0295 4 PMID:16189104 -3.5.2.6 oxacillin fusobacterium nucleatum 780.0 780.0 2 PMID:16870757 -3.5.2.6 oxacillin klebsiella pneumoniae 130.0 130.0 1 PMID:19477418 -3.5.2.6 oxacillin morganella morganii subsp. morganii 0.022 0.022 1 PMID:16495258 -3.5.2.6 oxacillin mycolicibacterium smegmatis 11.9 11.9 1 PMID:28421415 -3.5.2.6 oxacillin plasmid pgem-t-easy 600.0 450.0 2 PMID:19860471 -3.5.2.6 oxacillin plasmid rgn238 577.0 577.0 1 PMID:20086146 -3.5.2.6 oxacillin pseudomonas fluorescens 0.21 0.21 1 PMID:18312599 -3.5.2.6 oxacillin serratia fonticola 105.0 105.0 1 PMID:9300809 -3.5.2.6 oxacillin shewanella algae 5.0 5.0 1 PMID:15105119 -3.5.2.6 oxacillin staphylococcus aureus 8.0 8.0 1 PMID:10209286 -3.5.2.6 panipenem klebsiella pneumoniae 1.4 1.4 1 PMID:19477418 -3.5.2.6 panipenem metapseudomonas otitidis 500.0 500.0 1 PMID:25512428 -3.5.2.6 penicillin enterobacter cloacae 29.0 29.0 1 PMID:16189133 -3.5.2.6 penicillin pseudomonas aeruginosa 6.6 6.6 1 PMID:15561840 -3.5.2.6 penicillin g aeromonas enteropelogenes 27.0 27.0 1 PMID:20124004 -3.5.2.6 penicillin g bacillus anthracis 628.0 628.0 1 PMID:21369909 -3.5.2.6 penicillin g bacillus licheniformis 2612.0 2612.0 1 PMID:21705325 -3.5.2.6 penicillin g bacteroides fragilis 110.0 110.0 1 PMID:9126607 -3.5.2.6 penicillin g burkholderia pseudomallei 0.4 0.4 1 PMID:15793160 -3.5.2.6 penicillin g citrobacter freundii 23.0 23.0 1 PMID:18316524;PMID:18765691 -3.5.2.6 penicillin g elizabethkingia meningoseptica 280.0 280.0 1 * -3.5.2.6 penicillin g escherichia coli 1570.0 692.0 5 PMID:10438473;PMID:19228020;PMID:20591901 -3.5.2.6 penicillin g klebsiella pneumoniae 34.0 28.5 2 PMID:17944487;PMID:18316524;PMID:18765691 -3.5.2.6 penicillin g mycobacterium tuberculosis 9.33 9.33 1 PMID:17915954 -3.5.2.6 penicillin g mycolicibacterium smegmatis 27.6 27.6 1 PMID:28421415 -3.5.2.6 penicillin g pectobacterium carotovorum 2.0 2.0 1 PMID:18443127 -3.5.2.6 penicillin g plasmid pbg66 950.0 950.0 1 PMID:19812041 -3.5.2.6 penicillin g providencia stuartii 26.0 26.0 1 PMID:15328132 -3.5.2.6 penicillin g pseudomonas aeruginosa 890.0 757.0 5 PMID:11148033;PMID:18644957 -3.5.2.6 penicillin g pseudomonas luteola 31.0 31.0 1 PMID:19884377 -3.5.2.6 penicillin g staphylococcus aureus 210.0 163.5 4 PMID:1605608 -3.5.2.6 penicillin g stenotrophomonas maltophilia 600.0 505.0 2 PMID:14573595;PMID:9559809 -3.5.2.6 penicillin v mycobacterium tuberculosis 35.0 35.0 1 PMID:17915954 -3.5.2.6 phenoxymethylpenicillin bacillus licheniformis 2550.0 2550.0 1 PMID:1974463 -3.5.2.6 piperacillin achromobacter sp. sallbros1 3.3 3.3 1 PMID:22290947 -3.5.2.6 piperacillin achromobacter xylosoxidans 0.5 0.5 1 PMID:18362192 -3.5.2.6 piperacillin acinetobacter baumannii 0.2 0.2 1 PMID:16189095 -3.5.2.6 piperacillin acinetobacter bereziniae 2.2 2.2 1 PMID:22508298 -3.5.2.6 piperacillin aeromonas enteropelogenes 0.54 0.54 1 PMID:20124004 -3.5.2.6 piperacillin bacteroides fragilis 100.0 100.0 1 PMID:9126607 -3.5.2.6 piperacillin brachyspira pilosicoli 2.1 2.1 1 PMID:18212108 -3.5.2.6 piperacillin burkholderia cenocepacia 5.0 5.0 1 PMID:19075063 -3.5.2.6 piperacillin burkholderia pseudomallei 2.11 2.11 1 PMID:15793160 -3.5.2.6 piperacillin chryseobacterium indologenes 14.61 14.61 1 PMID:17470648 -3.5.2.6 piperacillin enterobacter cloacae 47.0 47.0 1 PMID:16189133 -3.5.2.6 piperacillin escherichia coli 940.0 770.0 3 PMID:10438473;PMID:17207608;PMID:8056282 -3.5.2.6 piperacillin janthinobacterium lividum 100.0 100.0 1 PMID:15561856 -3.5.2.6 piperacillin klebsiella aerogenes 2.7 2.7 1 PMID:18160520 -3.5.2.6 piperacillin klebsiella pneumoniae 677.0 19.0 4 PMID:17467221;PMID:18316524;PMID:21911565;PMID:29228168 -3.5.2.6 piperacillin kluyvera ascorbata 5.0 5.0 1 PMID:17196371 -3.5.2.6 piperacillin metapseudomonas otitidis 9.0 9.0 1 PMID:25512428 -3.5.2.6 piperacillin moraxella catarrhalis 51.0 49.0 2 PMID:1396750 -3.5.2.6 piperacillin morganella morganii subsp. morganii 1.5 1.5 1 PMID:16495258 -3.5.2.6 piperacillin mycobacterium tuberculosis 11.5 11.5 1 PMID:17915954 -3.5.2.6 piperacillin mycolicibacterium smegmatis 22.02 22.02 1 PMID:28421415 -3.5.2.6 piperacillin pectobacterium carotovorum 9.0 9.0 1 PMID:18443127 -3.5.2.6 piperacillin plasmid pbc 51.0 51.0 1 PMID:20421396 -3.5.2.6 piperacillin pseudomonas aeruginosa 374.0 321.0 8 PMID:15561840;PMID:16127048;PMID:18559652;PMID:18644957;PMID:20974864 -3.5.2.6 piperacillin pseudomonas luteola 8.0 8.0 1 PMID:19884377 -3.5.2.6 piperacillin pseudomonas putida 328.0 328.0 1 PMID:18757180 -3.5.2.6 piperacillin riemerella anatipestifer 0.47 0.47 1 PMID:35580446 -3.5.2.6 piperacillin serratia fonticola 255.0 149.85 2 PMID:17875998;PMID:9300809 -3.5.2.6 piperacillin shewanella algae 3.0 3.0 1 PMID:15105119 -3.5.2.6 piperacillin shouchella clausii 38.0 38.0 1 PMID:17846134 -3.5.2.6 piperacillin stenotrophomonas maltophilia 420.0 420.0 1 PMID:9559809 -3.5.2.6 piperacillin synthetic construct 976.0 937.0 2 PMID:19351161 -3.5.2.6 sulbactam chryseobacterium indologenes 3.3 3.3 1 PMID:17470648 -3.5.2.6 sulbactam escherichia coli 20.0 12.0 2 PMID:16251324;PMID:17207608 -3.5.2.6 tazobactam pseudomonas putida 8.2 8.2 1 PMID:18757180 -3.5.2.6 tebipenem mycobacterium tuberculosis 0.0005 0.0005 1 PMID:24846409 -3.5.2.6 temocillin klebsiella pneumoniae 0.3 0.3 1 PMID:19477418 -3.5.2.6 ticarcillin achromobacter xylosoxidans 0.1 0.1 1 PMID:18362192 -3.5.2.6 ticarcillin acinetobacter baumannii 0.3 0.3 1 PMID:16189095 -3.5.2.6 ticarcillin acinetobacter bereziniae 1.7 1.7 1 PMID:22508298 -3.5.2.6 ticarcillin burkholderia cenocepacia 15.0 15.0 1 PMID:19075063 -3.5.2.6 ticarcillin enterobacter cloacae 81.0 81.0 1 PMID:8807798 -3.5.2.6 ticarcillin escherichia coli 121.0 64.6 2 PMID:15561863;PMID:8056282 -3.5.2.6 ticarcillin klebsiella pneumoniae 84.0 46.0 2 PMID:15561863;PMID:18316524 -3.5.2.6 ticarcillin metapseudomonas otitidis 190.0 190.0 1 PMID:25512428 -3.5.2.6 ticarcillin mycolicibacterium smegmatis 1.722 1.722 1 PMID:28421415 -3.5.2.6 ticarcillin pectobacterium carotovorum 9.0 9.0 1 PMID:18443127 -3.5.2.6 ticarcillin pseudomonas aeruginosa 220.0 18.0 4 PMID:15561840;PMID:16127048;PMID:20974864;PMID:21041509 -3.5.2.6 ticarcillin pseudomonas luteola 5.0 5.0 1 PMID:19884377 -3.5.2.6 ticarcillin pseudomonas putida 6.9 6.9 1 PMID:12709317 -3.5.2.6 ticarcillin serratia fonticola 115.0 115.0 1 PMID:9300809 -3.5.2.6 ticarcillin shewanella algae 1.0 1.0 1 PMID:15105119 -3.5.2.6 ticarcillin shouchella clausii 5.0 5.0 1 PMID:17846134 -3.5.2.6 ticarcillin stenotrophomonas maltophilia 440.0 440.0 1 PMID:9559809 -3.5.2.9 5-oxo-l-proline rattus norvegicus 0.117 0.117 1 PMID:1181279 -3.5.3.1 1-nitro-3-guanidinobenzene rattus norvegicus 0.0015 0.0015 1 PMID:12020133 -3.5.3.1 4-guanidino-2-nitrophenylacetic acid rattus norvegicus 0.09 0.09 1 PMID:12020133 -3.5.3.1 4-guanidino-3-nitrobenzoic acid rattus norvegicus 0.058 0.058 1 PMID:12020133 -3.5.3.1 l-arg mammalia 2200.0 2200.0 1 * -3.5.3.1 l-arginine [bacillus] caldovelox 700.0 700.0 1 PMID:25447142 -3.5.3.1 l-arginine geobacillus thermodenitrificans 657.0 657.0 1 PMID:25908562 -3.5.3.1 l-arginine glaciozyma antarctica 2250.0 2250.0 1 PMID:38300354 -3.5.3.1 l-arginine helicobacter pylori 0.52 0.28 5 PMID:20381458;PMID:21190293;PMID:22031496 -3.5.3.1 l-arginine homo sapiens 1132.0 190.0 8 PMID:12859189;PMID:16128822;PMID:17212779;PMID:18957279;PMID:19093830;PMID:21945700;PMID:35742891 -3.5.3.1 l-arginine leishmania donovani 179.0 179.0 1 PMID:30831225 -3.5.3.1 l-arginine penicillium chrysogenum 0.27 0.25 3 PMID:25322968 -3.5.3.1 l-arginine plasmodium falciparum 3d7 24.8 24.8 1 PMID:19456858 -3.5.3.1 l-arginine rattus norvegicus 350.0 250.0 3 PMID:11278703;PMID:12020133;PMID:19093830 -3.5.3.1 l-arginine schistosoma mansoni 537.0 537.0 1 PMID:18723022 -3.5.3.1 l-arginine sulfobacillus acidophilus 458.3 458.3 1 PMID:32529376 -3.5.3.1 l-phenylalanine penicillium chrysogenum 0.94 0.46 3 PMID:25322968 -3.5.3.1 l-thioarginine rattus norvegicus 300.0 300.0 1 PMID:12020133 -3.5.3.1 s-(4-aminobutyl)isothiourea rattus norvegicus 3.33 3.33 1 PMID:12020133 -3.5.3.1 thioguanidino-valeric acid rattus norvegicus 0.013 0.013 1 PMID:12020133 -3.5.3.11 agmatine clostridium butyricum 0.0053 0.0053 1 PMID:38318350 -3.5.3.11 agmatine escherichia coli 120.0 61.0 2 PMID:33946272;PMID:38318350 -3.5.3.11 agmatine homo sapiens 3.0 3.0 1 PMID:17212779 -3.5.3.11 agmatine methanocaldococcus jannaschii 0.032 0.032 1 PMID:22439800 -3.5.3.11 agmatine neurospora crassa 77.0 77.0 1 PMID:34634482 -3.5.3.11 agmatine rattus norvegicus 1.0 0.95 2 PMID:25635913;PMID:32531922 -3.5.3.12 agmatine campylobacter jejuni subsp. jejuni serotype o:2 0.00533 0.00533 1 PMID:29190068 -3.5.3.12 agmatine helicobacter pylori 0.082 0.082 1 PMID:20036411 -3.5.3.12 agmatine listeria monocytogenes 34.28 34.28 1 PMID:23918931 -3.5.3.12 agmatine listeria monocytogenes serotype 1/2a 0.517 0.517 1 PMID:27034081 -3.5.3.12 agmatine pseudomonas aeruginosa 8.0 8.0 1 PMID:12634339 -3.5.3.13 n-formimino-d-glutamate pseudomonas aeruginosa 0.05 0.05 1 PMID:16475788 -3.5.3.13 n-formimino-l-glutamate pseudomonas aeruginosa 31.0 17.25 8 PMID:16475788;PMID:17128965 -3.5.3.13 n-formimino-l-isoleucine pseudomonas aeruginosa 0.019 0.019 1 PMID:16475788 -3.5.3.13 n-formimino-l-methionine pseudomonas aeruginosa 0.01 0.01 1 PMID:16475788 -3.5.3.15 2-acetyl-gly-arg-gly-lys-gly-gly-lys-gly-leu-gly-lys-gly-gly-ala-lys homo sapiens 0.45 0.45 1 PMID:20469888 -3.5.3.15 3-acetyl-arg-gly-lys-gly-gly-lys-gly-leu-gly-lys-gly-gly-ala-lys homo sapiens 0.48 0.48 1 PMID:20469888 -3.5.3.15 [histone h4]-l-arg homo sapiens 2.1 2.1 1 PMID:21466234 -3.5.3.15 ac-ala-gly-arg-gly-lys homo sapiens 0.59 0.39999999999999997 2 PMID:20469888 -3.5.3.15 ac-ser-ala-arg-gly-lys homo sapiens 1.13 0.875 2 PMID:20469888 -3.5.3.15 ac-ser-gly-ala-gly-lys-gly-gly-lys-gly-leu-gly-lys-gly-gly-ala-ala-arg-his-arg-lys-val homo sapiens 1.46 1.46 1 PMID:20469888 -3.5.3.15 ac-ser-gly-arg-ala-lys homo sapiens 0.98 0.98 1 PMID:20469888 -3.5.3.15 ac-ser-gly-arg-gly-acetyl-lys-gly-gly-acetyl-lys-gly-leu-gly-acetyl-lys-gly-gly-ala-acetyl-lys homo sapiens 1.08 0.825 2 PMID:20469888 -3.5.3.15 ac-ser-gly-arg-gly-ala homo sapiens 0.93 0.93 1 PMID:20469888 -3.5.3.15 ac-ser-gly-arg-gly-lys-gly-gly-lys-gly-leu-gly-lys-gly homo sapiens 2.83 2.83 1 PMID:20469888 -3.5.3.15 ac-ser-gly-arg-gly-lys-gly-gly-lys-gly-leu-gly-lys-gly-gly-ala homo sapiens 2.53 1.64 2 PMID:20469888 -3.5.3.15 ac-ser-gly-arg-gly-lys-gly-gly-lys-gly-leu-gly-lys-gly-gly-ala-ala-arg-his-arg-ala-val homo sapiens 0.77 0.77 1 PMID:20469888 -3.5.3.15 ac-ser-gly-arg-gly-lys-gly-gly-lys-gly-leu-gly-lys-gly-gly-ala-ala-arg-his-arg-lys-val homo sapiens 0.87 0.87 1 PMID:20469888 -3.5.3.15 ac-ser-gly-arg-gly-lys-gly-gly-lys-gly-leu-gly-lys-gly-gly-ala-lys homo sapiens 2.3 0.6 3 PMID:20469888 -3.5.3.15 ac-ser-gly-arg-gly-lys-gly-gly-lys-gly-leu-gly-lys-gly-gly-ala-lys-arg-his homo sapiens 4.92 2.29 3 PMID:20469888 -3.5.3.15 ac-ser-gly-arg-gly-lys-gly-gly-lys-gly-leu-gly-lys-gly-gly-ala-lys-arg-his-ala-ala-val homo sapiens 1.83 1.83 1 PMID:20469888 -3.5.3.15 ac-ser-gly-arg-gly-lys-gly-gly-lys-gly-leu-gly-lys-gly-gly-ala-lys-arg-his-arg-lys-val homo sapiens 3.39 0.81 3 PMID:20469888 -3.5.3.15 ac-ser-gly-arg-gly-lys-gly-gly-lys-gly-leu-gly-lys-gly-gly-ala-lys-lys-his-lys-ala-val homo sapiens 0.56 0.45000000000000007 2 PMID:20469888 -3.5.3.15 acetyl-l-arg homo sapiens 13.68 13.68 1 PMID:16091842 -3.5.3.15 acetyl-l-arg mus musculus 0.37 0.345 2 PMID:7872804 -3.5.3.15 acetyl-l-arg methyl ester homo sapiens 11.28 4.075 4 PMID:16091842 -3.5.3.15 acetyl-l-arg methyl ester mus musculus 4.41 4.26 2 PMID:7872804 -3.5.3.15 benzoyl-arg ethyl ester mus musculus 10.7 10.7 1 PMID:7872804 -3.5.3.15 benzoyl-arginine ethyl ester mus musculus 10.8 10.8 1 PMID:7872804 -3.5.3.15 benzoyl-l-arg homo sapiens 14.43 1.97 4 PMID:16091842 -3.5.3.15 benzoyl-l-arg mus musculus 1.41 1.26 2 PMID:7872804 -3.5.3.15 benzoyl-l-arg ethyl ester homo sapiens 15.24 1.73 5 PMID:16091842 -3.5.3.15 benzoyl-l-arg methyl ester mus musculus 5.74 5.715 2 PMID:7872804 -3.5.3.15 benzoyl-l-arg-nh2 mus musculus 5.51 5.41 2 PMID:7872804 -3.5.3.15 benzoyl-l-arginine homo sapiens 3.35 3.35 1 PMID:16060666 -3.5.3.15 benzoyl-l-arginine amide homo sapiens 6.0 4.38 2 PMID:16060666 -3.5.3.15 benzoyl-l-arginine ethyl ester homo sapiens 5.94 5.94 1 PMID:16060666 -3.5.3.15 benzoyl-l-arginine methyl ester homo sapiens 5.57 5.57 1 PMID:16060666 -3.5.3.15 dansyl-gly-arg homo sapiens 0.46 0.46 1 PMID:31052493 -3.5.3.15 ihareifdsr porphyromonas gingivalis 7.0 4.9399999999999995 2 PMID:30638292 -3.5.3.15 kdrnw homo sapiens 2.0 2.0 1 PMID:19040354 -3.5.3.15 l-arg mus musculus 0.52 0.37 2 PMID:7872804 -3.5.3.15 l-arg methyl ester mus musculus 0.31 0.24 2 PMID:7872804 -3.5.3.15 ldrge homo sapiens 2.9 2.9 1 PMID:19040354 -3.5.3.15 mwrhv homo sapiens 2.0 2.0 1 PMID:19040354 -3.5.3.15 n-alpha-benzoyl-l-arginine amide homo sapiens 3.57 2.76 3 PMID:20469888 -3.5.3.15 n-alpha-benzoyl-l-arginine ethyl ester homo sapiens 11.7 2.65 5 PMID:20469888;PMID:25621824;PMID:28209966 -3.5.3.15 n-alpha-benzoyl-l-arginine methyl ester homo sapiens 5.57 3.85 3 PMID:20469888 -3.5.3.15 nalpha-benzoyl l-arginine ethyl ester homo sapiens 2.8 2.8 1 PMID:21466234 -3.5.3.15 nalpha-benzoyl-l-arginine homo sapiens 0.63 0.63 1 PMID:24989433 -3.5.3.15 nalpha-benzoyl-l-arginine amide homo sapiens 0.32 0.32 1 PMID:24989433 -3.5.3.15 nalpha-benzoyl-l-arginine ethyl ester homo sapiens 13.4 8.3 2 PMID:21731701;PMID:24989433 -3.5.3.15 nalpha-benzoyl-l-arginine methyl ester homo sapiens 0.43 0.43 1 PMID:24989433 -3.5.3.15 ppgfspfr porphyromonas gingivalis 11.3 7.165 2 PMID:30638292 -3.5.3.15 tkqtarkstggk homo sapiens 0.7 0.7 1 PMID:19040354 -3.5.3.15 tstggrqgshh homo sapiens 1.3 1.3 1 PMID:19040354 -3.5.3.15 wsryh homo sapiens 1.8 1.8 1 PMID:19040354 -3.5.3.15 wtrge homo sapiens 3.3 3.3 1 PMID:19040354 -3.5.3.15 ywrdh homo sapiens 2.3 2.3 1 PMID:19040354 -3.5.3.17 3-guanidinopropionate pseudomonas aeruginosa 106.0 106.0 1 PMID:21600989 -3.5.3.17 4-guanidinobutyrate pseudomonas aeruginosa 57.6 57.6 1 PMID:21600989 -3.5.3.18 asymmetric nomega,nomega-dimethyl-l-arginine pseudomonas aeruginosa 1.27 1.27 1 PMID:35598478 -3.5.3.18 ng,ng-dimethyl-l-arginine bos taurus 0.27 0.27 1 PMID:9537995 -3.5.3.18 ng,ng-dimethyl-l-arginine pseudomonas aeruginosa 1.27 0.915 2 PMID:15865451;PMID:16634643 -3.5.3.18 ng,ng-dimethyl-l-homoarginine rattus norvegicus 0.009 0.009 1 PMID:2722865 -3.5.3.18 ng-amino-l-arginine pseudomonas aeruginosa 0.12 0.12 1 PMID:15865451 -3.5.3.18 ng-hydroxy-l-arginine pseudomonas aeruginosa 0.33 0.33 1 PMID:15865451 -3.5.3.18 ng-methyl-l-arginine pseudomonas aeruginosa 0.59 0.44999999999999996 2 PMID:15865451;PMID:16634643 -3.5.3.18 ng-monomethyl-l-arginine bos taurus 0.34 0.34 1 PMID:9537995 -3.5.3.18 ng-monomethyl-l-arginine rattus norvegicus 0.094 0.094 1 PMID:2722865 -3.5.3.18 nomega,nomega-dimethyl-l-arginine homo sapiens 0.014 0.014 1 PMID:19663506 -3.5.3.18 s-methyl-l-thiocitrulline homo sapiens 0.042 0.042 1 PMID:19663506 -3.5.3.18 s-methyl-l-thiocitrulline pseudomonas aeruginosa 1.3 1.07 2 PMID:15865451;PMID:16634643 -3.5.3.2 guanidinoacetate flavobacterium sp. 60.2 60.2 1 * -3.5.3.2 guanidinoacetate pseudomonas sp. 54.1 54.1 1 * -3.5.3.20 1,4-diguanidinobutane pseudomonas putida 1330.0 1330.0 1 * -3.5.3.24 agmatine thermococcus kodakarensis 0.00186 0.00186 1 PMID:20675472 -3.5.3.24 n1-aminopropylagmatine thermococcus kodakarensis 0.001 0.001 1 PMID:20675472 -3.5.3.26 (s)-2-ureidoglycine arabidopsis thaliana 761.0 761.0 1 PMID:22493446 -3.5.3.27 l-arginine anabaena sp. 4.88 2.666 2 PMID:32198136 -3.5.3.27 l-arginine streptomyces sp. 0.148 0.148 1 PMID:33886165 -3.5.3.27 l-arginine synechocystis sp. pcc 6803 6.4 6.4 1 PMID:29632414 -3.5.3.27 l-citrulline streptomyces sp. 0.06 0.06 1 PMID:33886165 -3.5.3.3 creatine pseudomonas putida 0.246 0.246 1 PMID:1015832 -3.5.3.4 allantoate chlamydomonas reinhardtii 750.0 750.0 1 PMID:10860551 -3.5.3.6 agmatine-l-arg porphyromonas gingivalis 0.007 0.007 1 PMID:19545534 -3.5.3.6 benzoyl-l-arginine ethyl ester porphyromonas gingivalis 0.019 0.019 1 PMID:19545534 -3.5.3.6 bradykinin antagonist-l-arg porphyromonas gingivalis 0.0068 0.0068 1 PMID:19545534 -3.5.3.6 bradykinin-l-arg porphyromonas gingivalis 0.043 0.043 1 PMID:19545534 -3.5.3.6 d-arg porphyromonas gingivalis 0.058 0.058 1 PMID:19545534 -3.5.3.6 homoarginine porphyromonas gingivalis 0.11 0.11 1 PMID:19545534 -3.5.3.6 l-alanine aspergillus fumigatus 0.006 0.0034 3 PMID:25582958 -3.5.3.6 l-arg bacillus cereus 3.2 3.2 1 PMID:18366187 -3.5.3.6 l-arg burkholderia mallei 1.3 1.3 1 PMID:18366187 -3.5.3.6 l-arg escherichia coli 3.2 3.2 1 PMID:18366187 -3.5.3.6 l-arg metamycoplasma arthritidis 29.0 29.0 1 PMID:681336 -3.5.3.6 l-arg porphyromonas gingivalis 0.22 0.22 1 PMID:19545534 -3.5.3.6 l-arg pseudomonas aeruginosa 6.3 6.3 2 PMID:16430212;PMID:18366187 -3.5.3.6 l-arginine aspergillus fumigatus 0.00478 0.00475 3 PMID:25582958 -3.5.3.6 l-arginine bacillus cereus 4.4 4.4 1 PMID:18205354 -3.5.3.6 l-arginine burkholderia mallei 1.3 1.3 1 PMID:18205354 -3.5.3.6 l-arginine enterococcus faecalis 309.0 309.0 1 PMID:30047723 -3.5.3.6 l-arginine escherichia coli 3.2 3.2 1 PMID:18205354 -3.5.3.6 l-arginine giardia duodenalis 2.6 2.6 2 PMID:18205354;PMID:19640561 -3.5.3.6 l-arginine metamycoplasma hominis 0.151 0.151 1 PMID:17080455 -3.5.3.6 l-arginine pseudomonas aeruginosa 6.3 6.3 3 PMID:16430212;PMID:18205354 -3.5.3.6 l-arginine pseudomonas plecoglossicida 21.8 10.850000000000001 4 PMID:20157910;PMID:25104032;PMID:31062871 -3.5.3.6 l-arginine streptococcus pyogenes 35.0 35.0 1 PMID:26695833 -3.5.3.6 l-arginine ethyl ester giardia duodenalis 2.3 2.3 1 PMID:19640561 -3.5.3.6 l-arginine hydroxamate porphyromonas gingivalis 0.15 0.15 1 PMID:19545534 -3.5.3.6 l-canavanine bacillus cereus 0.46 0.46 1 PMID:18205354 -3.5.3.6 l-canavanine burkholderia mallei 0.09 0.09 1 PMID:18205354 -3.5.3.6 l-canavanine escherichia coli 0.42 0.42 1 PMID:18205354 -3.5.3.6 l-canavanine giardia duodenalis 0.32 0.32 1 PMID:18205354 -3.5.3.6 l-canavanine pseudomonas aeruginosa 0.62 0.62 2 PMID:18205354 -3.5.3.6 l-canavanine-l-arg porphyromonas gingivalis 0.0052 0.0052 1 PMID:19545534 -3.5.3.6 l-lysine aspergillus fumigatus 0.0043 0.004 3 PMID:25582958 -3.5.3.6 l-pro-l-arg-l-phe porphyromonas gingivalis 0.0075 0.0075 1 PMID:19545534 -3.5.3.6 l-pro-l-phe-l-arg porphyromonas gingivalis 0.17 0.17 1 PMID:19545534 -3.5.3.6 n-alpha-benzoyl-l-arginine porphyromonas gingivalis 0.12 0.12 1 PMID:19545534 -3.5.3.6 n-alpha-benzoyl-l-arginine ethyl ester homo sapiens 2.65 2.65 1 PMID:25621824 -3.5.3.6 nalpha-benzoyl-l-arginine giardia duodenalis 2.5 2.5 1 PMID:19640561 -3.5.3.6 nomega-amino-arg pseudomonas aeruginosa 7.0 7.0 1 PMID:16430212 -3.5.3.6 nomega-amino-l-arginine giardia duodenalis 0.58 0.58 1 PMID:19640561 -3.5.3.6 nomega-amino-l-arginine pseudomonas aeruginosa 7.0 7.0 1 PMID:16430212 -3.5.3.6 nomega-hydroxy-l-arginine porphyromonas gingivalis 0.0046 0.0046 1 PMID:19545534 -3.5.3.6 nomega-methyl-arg pseudomonas aeruginosa 0.01 0.01 1 PMID:16430212 -3.5.3.6 nomega-methyl-l-arginine pseudomonas aeruginosa 1.0 1.0 1 PMID:16430212 -3.5.3.7 4-guanidinobutyrate pseudomonas aeruginosa 1012.0 553.35 2 PMID:12029055;PMID:21600989 -3.5.3.8 n-formimidoyl-l-glutamate trypanosoma cruzi 200.0 200.0 1 PMID:24261485 -3.5.3.9 allantoate phaseolus vulgaris 18.0 18.0 1 PMID:24460648 -3.5.4.1 2-thiocytosine escherichia coli 22.3 12.285 2 PMID:10669789 -3.5.4.1 3-oxauracil escherichia coli 2.3 2.3 1 PMID:21545144 -3.5.4.1 5-azacytosine escherichia coli 2.68 1.665 2 PMID:10669789 -3.5.4.1 5-fluorocytosine aspergillus niger 0.093 0.091 2 PMID:36627557 -3.5.4.1 5-fluorocytosine escherichia coli 75.6 45.355000000000004 6 PMID:10669789;PMID:15248753;PMID:15381761;PMID:18517259;PMID:19487291 -3.5.4.1 5-fluorocytosine saccharomyces cerevisiae 21.0 17.9 4 PMID:15823054;PMID:18291415;PMID:22208667 -3.5.4.1 6-azacytosine escherichia coli 186.0 95.7 2 PMID:10669789 -3.5.4.1 creatinine escherichia coli 5.6 5.6 1 PMID:21545144 -3.5.4.1 cytosine aspergillus niger 0.089 0.08299999999999999 2 PMID:36627557 -3.5.4.1 cytosine escherichia coli 185.0 165.0 7 PMID:10669789;PMID:15248753;PMID:15381761;PMID:18517259;PMID:19487291;PMID:21545144 -3.5.4.1 cytosine saccharomyces cerevisiae 170.0 130.5 2 PMID:15823054;PMID:18291415 -3.5.4.1 isocytosine escherichia coli 5.1 5.1 1 PMID:21545144 -3.5.4.10 5-formamido-1-(5-phospho-d-ribosyl)imidazole-4-carboxamide archaeoglobus fulgidus 1.32 1.32 1 PMID:316224277 -3.5.4.10 5-formamido-1-(5-phospho-d-ribosyl)imidazole-4-carboxamide escherichia coli 3.63 3.63 1 PMID:29799386 -3.5.4.10 5-formamido-1-(5-phospho-d-ribosyl)imidazole-4-carboxamide thermococcus kodakarensis 0.48 0.48 1 PMID:316224277 -3.5.4.10 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide homo sapiens 8.6 8.6 2 PMID:11096114;PMID:14756554 -3.5.4.11 2-amino-4-oxo-3,4-dihydropteridine-6-carboxylic acid unidentified prokaryotic organism 1.01 1.01 1 PMID:20415463 -3.5.4.11 2-aminopteridine-4,7(1h,8h)-dione unidentified prokaryotic organism 1.05 1.05 1 PMID:20415463 -3.5.4.12 dcmp equus asinus 1400.0 1400.0 1 PMID:1898061 -3.5.4.12 dcmp geobacillus thermodenitrificans 162.5 89.375 2 PMID:31954084 -3.5.4.12 dcmp homo sapiens 960.0 960.0 1 PMID:8448179 -3.5.4.12 dcmp paramecium bursaria chlorella virus 1 24.9 24.9 1 PMID:17475641 -3.5.4.12 dcmp tequatrovirus t4 466.0 255.0 5 PMID:10777550 -3.5.4.12 dctp paramecium bursaria chlorella virus 1 5.7 5.7 1 PMID:17475641 -3.5.4.13 dcmp paramecium bursaria chlorella virus 1 24.9 24.9 1 PMID:17475641 -3.5.4.13 dctp escherichia coli 1.24 1.24 1 PMID:17996716 -3.5.4.13 dctp paramecium bursaria chlorella virus 1 5.7 5.7 1 PMID:17475641 -3.5.4.15 2'-deoxyguanosine arabidopsis thaliana 0.611 0.611 1 PMID:24130159 -3.5.4.15 guanosine arabidopsis thaliana 1.753 1.753 1 PMID:24130159 -3.5.4.16 gdp thermus thermophilus 0.0017 0.0017 1 PMID:16169877 -3.5.4.16 gtp bacillus subtilis 0.0011 0.0011 1 PMID:19767425 -3.5.4.16 gtp neisseria gonorrhoeae 0.000265 0.000265 1 PMID:28126741 -3.5.4.16 gtp plasmodium falciparum 0.039 0.039 1 PMID:24745605 -3.5.4.16 gtp thermus thermophilus 0.0035 0.0035 1 PMID:16169877 -3.5.4.19 1-(5-phosphoribosyl)-amp methanothermobacter thermautotrophicus 9.9 3.345 4 PMID:16042384 -3.5.4.2 2,6-diaminopurine alteromonas macleodii 1.8 1.8 1 PMID:21710971 -3.5.4.2 2,6-diaminopurine blastobotrys adeninivorans 12.3 12.3 1 PMID:23902582 -3.5.4.2 2,6-diaminopurine paenarthrobacter aurescens 6.9 6.9 1 PMID:21710971 -3.5.4.2 2,6-diaminopurine pseudomonas aeruginosa 17.0 17.0 1 PMID:21710971 -3.5.4.2 6-chloropurine alteromonas macleodii 0.84 0.84 1 PMID:21710971 -3.5.4.2 6-chloropurine burkholderia sp. 0.42 0.42 1 PMID:21710971 -3.5.4.2 6-chloropurine pseudomonas aeruginosa 1.9 1.9 1 PMID:21710971 -3.5.4.2 6-methoxypurine alteromonas macleodii 0.52 0.52 1 PMID:21710971 -3.5.4.2 6-methoxypurine burkholderia sp. 2.2 2.2 1 PMID:21710971 -3.5.4.2 6-methoxypurine paenarthrobacter aurescens 1.9 1.9 1 PMID:21710971 -3.5.4.2 6-methoxypurine pseudomonas aeruginosa 7.1 7.1 1 PMID:21710971 -3.5.4.2 adenine alteromonas macleodii 62.0 62.0 1 PMID:21710971 -3.5.4.2 adenine blastobotrys adeninivorans 20.8 20.8 1 PMID:23902582 -3.5.4.2 adenine burkholderia sp. 56.0 56.0 1 PMID:21710971 -3.5.4.2 adenine escherichia coli 200.0 185.0 5 PMID:21247091 -3.5.4.2 adenine kluyveromyces lactis 8.1 8.1 1 PMID:30555824 -3.5.4.2 adenine leishmania donovani 16.75 16.75 1 PMID:22238346 -3.5.4.2 adenine methanocaldococcus jannaschii 221.0 221.0 1 PMID:26990095 -3.5.4.2 adenine paenarthrobacter aurescens 61.0 61.0 1 PMID:21710971 -3.5.4.2 adenine pseudomonas aeruginosa 6.0 6.0 1 PMID:21710971 -3.5.4.2 adenine saccharomyces cerevisiae 5.5 5.5 2 PMID:18673302 -3.5.4.2 adenine schizosaccharomyces pombe 13.4 13.4 2 PMID:18673302 -3.5.4.2 n-6-methyladenine alteromonas macleodii 0.48 0.48 1 PMID:21710971 -3.5.4.2 n-6-methyladenine pseudomonas aeruginosa 1.28 1.28 1 PMID:21710971 -3.5.4.21 creatinine corynebacterium glutamicum 74.5 74.5 1 PMID:32039507 -3.5.4.22 1-pyrroline-4-hydroxy-2-carboxylate pseudomonas putida 1.19 1.19 1 PMID:22833679 -3.5.4.23 blasticidin s aspergillus terreus 770.0 770.0 1 PMID:11779186 -3.5.4.25 2-amino-5-formylamino-6-ribosylamino-4(3h)-pyrimidinone 5'-triphosphate bacillus subtilis 0.05 0.05 1 PMID:19583770 -3.5.4.25 gtp bacillus subtilis 0.035 0.035 1 PMID:19583770 -3.5.4.25 gtp escherichia coli 0.15 0.107 2 PMID:11553632;PMID:9211333 -3.5.4.25 gtp mycobacterium tuberculosis 0.005 0.00415 2 PMID:23999287 -3.5.4.25 gtp streptomyces coelicolor 432.0 66.0 25 PMID:17002314;PMID:18281960 -3.5.4.28 s-adenosyl-l-homocysteine methanocaldococcus jannaschii 1300.0 1300.0 1 PMID:24375099 -3.5.4.28 s-adenosyl-l-homocysteine streptomyces albus 26.0 26.0 1 PMID:2592350 -3.5.4.29 gtp methanocaldococcus jannaschii 0.5 0.425 2 PMID:12475257 -3.5.4.3 1-methylguanine escherichia coli 0.08 0.08 1 PMID:31283204 -3.5.4.3 7,8-dihydropterin drosophila melanogaster 16.3 16.3 1 PMID:19567870 -3.5.4.3 8-azaguanine escherichia coli 7.0 7.0 1 PMID:31283204 -3.5.4.3 ammeline escherichia coli 1.0 1.0 1 PMID:31283204 -3.5.4.3 ammeline saccharomyces cerevisiae 2.8 2.8 1 PMID:31283204 -3.5.4.3 guanine blastobotrys adeninivorans 3.9 2.7 2 PMID:24481069 -3.5.4.3 guanine drosophila melanogaster 649.0 649.0 1 PMID:19567870 -3.5.4.3 guanine escherichia coli 2.8 2.8 1 PMID:31283204 -3.5.4.3 guanine kluyveromyces lactis 7.3 7.3 1 PMID:30555824 -3.5.4.3 guanine nitrosomonas europaea 15.0 15.0 1 PMID:34010666 -3.5.4.3 guanine saccharomyces cerevisiae 8.9 8.9 1 PMID:31283204 -3.5.4.31 adenosine methanocaldococcus jannaschii 110.0 110.0 1 PMID:24375099 -3.5.4.31 adenosine pseudomonas aeruginosa 17.1 17.1 1 PMID:23050701 -3.5.4.31 adenosine thermotoga maritima 2.3 2.3 1 PMID:17603473 -3.5.4.31 s-methyl-5'-thioadenosine methanocaldococcus jannaschii 160.0 160.0 2 PMID:24375099 -3.5.4.31 s-methyl-5'-thioadenosine plasmodium falciparum 13.92 13.92 1 PMID:31002765 -3.5.4.31 s-methyl-5'-thioadenosine pseudomonas aeruginosa 24.6 24.6 1 PMID:23050701 -3.5.4.31 s-methyl-5'-thioadenosine thermotoga maritima 7.2 7.2 1 PMID:17603473 -3.5.4.32 guanine pseudomonas aeruginosa 3.3 3.3 1 PMID:20088583 -3.5.4.32 guanine unidentified 52.0 52.0 1 PMID:20088583 -3.5.4.32 isocytosine pseudomonas aeruginosa 3.9 3.9 1 PMID:20088583 -3.5.4.32 isocytosine unidentified 62.0 62.0 1 PMID:20088583 -3.5.4.33 adenine34 in trnaval trypanosoma brucei 0.0032 0.0032 1 PMID:21507956;PMID:21602302 -3.5.4.34 adenine37 in trnaala saccharomyces cerevisiae 0.0705 0.0705 1 PMID:9707437 -3.5.4.37 8-azaadenine in double-stranded rna homo sapiens 0.0072 0.0072 1 PMID:12952466 -3.5.4.37 adenine in double-stranded rna homo sapiens 0.0012 0.0012 1 PMID:12952466 -3.5.4.38 ccca homo sapiens 0.0125 0.0071 2 PMID:31448897 -3.5.4.38 ttca homo sapiens 0.0145 0.0128 2 PMID:31448897 -3.5.4.4 5'-methylthioadenosine plasmodium berghei 0.35 0.35 1 PMID:19728741 -3.5.4.4 5'-methylthioadenosine plasmodium cynomolgi 0.31 0.31 1 PMID:19728741 -3.5.4.4 5'-methylthioadenosine plasmodium falciparum 13.92 9.86 2 PMID:19728741;PMID:31002765 -3.5.4.4 5'-methylthioadenosine plasmodium knowlesi 0.51 0.51 1 PMID:19728741 -3.5.4.4 5'-methylthioadenosine plasmodium vivax 0.13 0.13 1 PMID:19728741 -3.5.4.4 adenosine arabidopsis thaliana 0.005 0.005 1 PMID:18673302 -3.5.4.4 adenosine camelus dromedarius 18.5 18.5 1 PMID:12379282 -3.5.4.4 adenosine homo sapiens 180.0 93.74 3 PMID:18680557;PMID:31002765;PMID:34981765 -3.5.4.4 adenosine methanocaldococcus jannaschii 110.0 110.0 1 PMID:24375099 -3.5.4.4 adenosine plasmodium berghei 4.7 4.7 1 PMID:19728741 -3.5.4.4 adenosine plasmodium cynomolgi 5.3 5.3 1 PMID:19728741 -3.5.4.4 adenosine plasmodium falciparum 5.6 4.85 2 PMID:19728741;PMID:31002765 -3.5.4.4 adenosine plasmodium gallinaceum 1.9 1.9 1 PMID:19728741 -3.5.4.4 adenosine plasmodium knowlesi 6.8 6.8 1 PMID:19728741 -3.5.4.4 adenosine plasmodium vivax 1.8 1.8 1 PMID:19728741 -3.5.4.4 adenosine streptomyces coelicolor 11.5 11.5 1 PMID:21511036 -3.5.4.40 1-(6-amino-9h-purin-9-yl)-1-deoxy-n-ethyl-beta-d-ribofuranuronamide acidothermus cellulolyticus 0.007 0.007 1 PMID:23972005 -3.5.4.40 2'-deoxyadenosine deinococcus radiodurans 0.72 0.72 1 PMID:23972005 -3.5.4.40 5'-deoxyadenosine nitratiruptor sp. sb155-2 0.017 0.017 1 PMID:23972005 -3.5.4.40 5'-methylthioadenosine nitratiruptor sp. sb155-2 0.31 0.31 1 PMID:23972005 -3.5.4.40 5'-methylthioadenosine streptomyces avermitilis 0.4 0.4 1 PMID:23972005 -3.5.4.40 6-amino-6-deoxyfutalosine acidothermus cellulolyticus 6.8 6.8 1 PMID:23972005 -3.5.4.40 6-amino-6-deoxyfutalosine deinococcus radiodurans 8.6 8.6 1 PMID:23972005 -3.5.4.40 6-amino-6-deoxyfutalosine nitratiruptor sp. sb155-2 1.2 1.2 1 PMID:23972005 -3.5.4.40 6-amino-6-deoxyfutalosine streptomyces avermitilis 3.8 3.8 1 PMID:23972005 -3.5.4.41 5'-deoxyadenosine methanocaldococcus jannaschii 120000.0 120000.0 1 PMID:24375099 -3.5.4.42 ammelide pseudomonas sp. adp 26.2 26.2 1 PMID:26390431 -3.5.4.46 3',5'-cyclic amp leptospira interrogans serovar copenhageni str. fiocruz l1-130 46.0 46.0 1 PMID:24074367 -3.5.4.5 2'-deoxycytidine mycobacterium tuberculosis 3.5 3.5 1 PMID:20035876 -3.5.4.5 2'-deoxycytidine trypanosoma brucei brucei 448.409 448.409 1 PMID:31391279 -3.5.4.5 5-methyl-2'-deoxycytidine trypanosoma brucei brucei 2.093 2.093 1 PMID:31391279 -3.5.4.5 cytidine mycobacterium tuberculosis 4.85 4.824999999999999 2 PMID:20035876 -3.5.4.5 cytidine trypanosoma brucei brucei 12.427 12.427 1 PMID:31391279 -3.5.4.6 amp helix pomatia 170.0 170.0 1 PMID:37471401 -3.5.4.9 5,10-methenyltetrahydrofolate escherichia coli 40.9 40.9 1 PMID:25988590 -3.5.4.9 methenyltetrahydrofolate homo sapiens 134.0 134.0 1 PMID:11004530 -3.5.5.1 2-chloromandelonitrile uncultured organism 1.3 1.3 1 PMID:28687857 -3.5.5.1 2-cyanopyridine rhodococcus rhodochrous 0.00146 0.00146 1 PMID:18412544 -3.5.5.1 3-(4-chlorophenyl)pentanedinitrile synechocystis sp. pcc 6803 0.43 0.43 1 * -3.5.5.1 3-aminobenzonitrile rhodococcus rhodochrous 0.000288 0.000288 1 PMID:19903476 -3.5.5.1 3-anilinoproprionitrile saccharolobus solfataricus 0.28 0.28 1 PMID:16156792 -3.5.5.1 3-chlorobenzonitrile aeribacillus pallidus 1370.0 1370.0 1 PMID:10591020 -3.5.5.1 3-chloromandelonitrile uncultured organism 1.98 1.98 1 PMID:28687857 -3.5.5.1 3-methylbenzonitrile rhodococcus rhodochrous 0.000198 0.000198 1 PMID:19903476 -3.5.5.1 3-phenylpropionitrile brassica rapa 79.7 79.7 1 PMID:20507526 -3.5.5.1 4-aminobenzonitrile rhodococcus rhodochrous 0.000283 0.000283 1 PMID:19903476 -3.5.5.1 4-chlorobutyronitrile aeribacillus pallidus 11100.0 11100.0 1 PMID:10591020 -3.5.5.1 4-chloromandelonitrile uncultured organism 2.2 2.2 1 PMID:28687857 -3.5.5.1 4-cyanopyridine aeribacillus pallidus 43900.0 43900.0 1 PMID:10591020 -3.5.5.1 4-methylbenzonitrile rhodococcus rhodochrous 0.000695 0.000695 1 PMID:19903476 -3.5.5.1 4-phenylbutyronitrile brassica rapa 15.8 15.8 1 PMID:20507526 -3.5.5.1 allyl cyanide brassica rapa 19.8 19.8 1 PMID:20507526 -3.5.5.1 benzonitrile aeribacillus pallidus 14400.0 14400.0 1 PMID:10591020 -3.5.5.1 benzonitrile rhodococcus rhodochrous 0.00131 0.0007195 2 PMID:18412544;PMID:19903476 -3.5.5.1 benzonitrile saccharolobus solfataricus 0.09 0.09 1 PMID:16156792 -3.5.5.1 benzoylacetonitrile hoeflea phototrophica 170.0 170.0 1 PMID:29744634 -3.5.5.1 heptanenitrile brassica rapa 40.8 40.8 1 PMID:20507526 -3.5.5.1 iminodiacetonitrile acidovorax facilis 7.47 7.47 1 PMID:29753012 -3.5.5.1 iminodiacetonitrile paenarthrobacter aurescens 1.57 1.57 2 PMID:25742970 -3.5.5.1 indole-3-acetonitrile brassica rapa 0.29 0.29 1 PMID:20507526 -3.5.5.1 indole-3-acetonitrile zea mays 0.13 0.13 1 PMID:18182427 -3.5.5.1 isobutylsuccinonitrile arabis alpina 37.7 24.3 3 PMID:35750945 -3.5.5.1 isobutylsuccinonitrile brassica rapa 37.7 24.3 3 PMID:35750945 -3.5.5.1 m-tolunitrile rhodococcus rhodochrous 0.00198 0.00198 1 PMID:18412544 -3.5.5.1 malononitrile saccharolobus solfataricus 0.14 0.14 1 PMID:16156792 -3.5.5.1 mandelonitrile alcaligenes faecalis 0.083 0.0775 2 * -3.5.5.1 mandelonitrile alcaligenes sp. 175.0 175.0 1 * -3.5.5.1 mandelonitrile uncultured organism 4.6 4.6 1 PMID:28687857 -3.5.5.1 phenylglycinenitrile saccharolobus solfataricus 0.04 0.04 1 PMID:16156792 -3.5.5.1 succinonitrile uncultured burkholderiaceae bacterium 0.472 0.472 1 PMID:26868129 -3.5.5.1 trichloroacetonitrile saccharolobus solfataricus 0.01 0.01 1 PMID:16156792 -3.5.5.4 3-cyano-l-alanine brassica rapa 19.4 19.4 1 PMID:20507526 -3.5.5.4 3-cyano-l-alanine zea mays 0.001 0.001 1 PMID:18182427 -3.5.5.5 indole 3-acetonitrile pseudomonas putida 13.4 13.4 1 PMID:16341723 -3.5.5.5 mandelonitrile alcaligenes sp. 26.0 26.0 1 PMID:24712720 -3.5.5.5 mandelonitrile pseudomonas putida 11.8 11.8 1 PMID:16341723 -3.5.5.5 phenyl acetonitrile pseudomonas putida 18.85 9.975000000000001 2 PMID:16341723 -3.5.5.5 phenylacetonitrile alcaligenes faecalis 142.0 142.0 1 PMID:33113984 -3.5.5.5 phenylacetonitrile bradyrhizobium japonicum 1.85 1.85 1 PMID:18061298 -3.5.5.7 2-butenenitrile synechocystis sp. 0.19 0.19 1 PMID:25450592 -3.5.5.7 2-cyanopyridine rhodococcus rhodochrous 0.000175 0.000175 1 PMID:18412544 -3.5.5.7 2-cyanopyridine synechocystis sp. 1.8 1.8 1 PMID:25450592 -3.5.5.7 3-chloropropionitrile synechocystis sp. pcc 6803 8.31 8.31 1 PMID:37191513 -3.5.5.7 3-cyanopyridine synechocystis sp. 0.45 0.45 1 PMID:25450592 -3.5.5.7 3-cyanopyridine synechocystis sp. pcc 6803 1.64 1.64 1 PMID:37191513 -3.5.5.7 acrylonitrile pseudomonas fluorescens 0.33 0.33 1 PMID:19153727 -3.5.5.7 adiponitrile rhodococcus rhodochrous 0.0038 0.00213 2 PMID:18412544 -3.5.5.7 benzonitrile pseudomonas fluorescens 0.22 0.22 1 PMID:19153727 -3.5.5.7 benzonitrile rhodococcus rhodochrous 0.00015 0.00015 1 PMID:18412544 -3.5.5.7 benzonitrile synechocystis sp. 0.65 0.65 1 PMID:25450592 -3.5.5.7 fumaronitrile pseudomonas fluorescens 9.2 9.2 1 PMID:19153727 -3.5.5.7 fumaronitrile synechocystis sp. 15.13 15.13 1 PMID:25450592 -3.5.5.7 glutaronitrile pseudomonas fluorescens 5.0 5.0 1 PMID:19153727 -3.5.5.7 glutaronitrile rhodococcus rhodochrous 0.024 0.012145 2 PMID:18412544 -3.5.5.7 m-tolunitrile rhodococcus rhodochrous 0.00024 0.00024 1 PMID:18412544 -3.5.5.7 propionitrile pseudomonas fluorescens 0.17 0.17 1 PMID:19153727 -3.5.5.7 sebaconitrile pseudomonas fluorescens 3.3 3.3 1 PMID:19153727 -3.5.5.7 succinonitrile pseudomonas fluorescens 8.8 8.8 1 PMID:19153727 -3.5.5.7 succinonitrile thermotoga maritima 0.44 0.44 1 PMID:26059515 -3.5.5.8 methacrylonitrile thiobacillus thioparus 57.0 57.0 1 PMID:23453853 -3.5.99.11 2-aminomuconate ectopseudomonas oleovorans 208.0 208.0 1 PMID:9573204 -3.5.99.13 2-(4-fluoro-1h-indol-3-yl)ethanamine escherichia coli 0.058 0.058 1 PMID:16481164 -3.5.99.13 2-(4-methyl-1h-indol-3-yl)ethanamine escherichia coli 0.0031 0.0031 1 PMID:16481164 -3.5.99.13 2-(5-fluoro-1h-indol-3-yl)ethanamine escherichia coli 0.0072 0.0072 1 PMID:16481164 -3.5.99.13 2-(6-fluoro-1h-indol-3-yl)ethanamine escherichia coli 0.0093 0.0093 1 PMID:16481164 -3.5.99.13 2-(7-fluoro-1h-indol-3-yl)ethanamine escherichia coli 0.0018 0.0018 1 PMID:16481164 -3.5.99.13 2-(7-methyl-1h-indol-3-yl)ethanamine escherichia coli 0.0048 0.0048 1 PMID:16481164 -3.5.99.13 2-benzofuran-3-yl-ethylamine escherichia coli 0.0038 0.0038 1 PMID:16481164 -3.5.99.13 3-(2-aminoethyl)-1h-indol-5-ol escherichia coli 0.0016 0.0016 1 PMID:16481164 -3.5.99.13 5-fluoro-tryptamine rauvolfia serpentina 37.46 20.43 2 PMID:17884630 -3.5.99.13 5-hydroxy-tryptamine rauvolfia serpentina 562.1 281.0625 2 PMID:17884630 -3.5.99.13 6-fluoro-tryptamine rauvolfia serpentina 23.37 20.134999999999998 2 PMID:17884630 -3.5.99.13 6-methoxy-tryptamine rauvolfia serpentina 5.32 5.32 1 PMID:17884630 -3.5.99.13 6-methyl-tryptamine rauvolfia serpentina 2.32 2.32 1 PMID:17884630 -3.5.99.13 secologanin rauvolfia serpentina 4.5 4.5 1 * -3.5.99.13 serotonin rauvolfia serpentina 11.13 11.13 1 PMID:18280746 -3.5.99.13 tryptamine catharanthus roseus 1.3 0.651 2 PMID:17719488;PMID:18280746 -3.5.99.13 tryptamine escherichia coli 0.015 0.015 1 PMID:16481164 -3.5.99.13 tryptamine rauvolfia serpentina 10.65 10.65 3 PMID:17884630;PMID:18280746 -3.5.99.14 (3,4-dihydroxyphenyl)acetaldehyde thalictrum flavum 7.0 7.0 1 PMID:17696451 -3.5.99.14 3-(2-aminoethyl)phenol thalictrum flavum 6.0 6.0 1 PMID:17696451 -3.5.99.14 4-(2-aminoethyl)benzene-1,2-diol thalictrum flavum 7.0 6.7 2 PMID:17696451 -3.5.99.14 4-biphenylaldehyde thalictrum flavum 0.001 0.001 1 PMID:38647611 -3.5.99.14 4-hydroxyphenylacetaldehyde corydalis chinensis 5.3 5.3 1 PMID:27991536 -3.5.99.14 4-hydroxyphenylacetaldehyde nandina domestica 1.7 1.7 1 PMID:27991536 -3.5.99.14 4-hydroxyphenylacetaldehyde thalictrum flavum 6.4 6.0 4 PMID:17696451;PMID:19004827 -3.5.99.14 5-(2-aminoethyl)-2-methoxyphenol thalictrum flavum 6.0 6.0 1 PMID:17696451 -3.5.99.14 benzaldehyde thalictrum flavum 0.237 0.237 1 PMID:38647611 -3.5.99.14 dopamine corydalis chinensis 5.8 5.8 1 PMID:27991536 -3.5.99.14 dopamine nandina domestica 2.4 2.4 1 PMID:27991536 -3.5.99.2 4-amino-5-aminomethyl-2-methylpyrimidine helicobacter pylori 0.003 0.003 1 PMID:19780837 -3.5.99.2 thiamine aneurinibacillus aneurinilyticus 4.83 4.83 1 PMID:440095 -3.5.99.2 thiamine staphylococcus aureus 0.00407 0.002885 2 PMID:19888457;PMID:24311574 -3.5.99.5 2-aminomuconate ectopseudomonas oleovorans 208.0 208.0 1 PMID:9573204 -3.5.99.6 alpha-d-glucosamine 6-phosphate bacillus subtilis 110.0 110.0 1 PMID:27002132 -3.5.99.6 alpha-d-glucosamine 6-phosphate escherichia coli 220.0 189.0 2 PMID:24787711;PMID:27002132 -3.5.99.6 alpha-d-glucosamine 6-phosphate staphylococcus aureus 105.0 105.0 1 PMID:30411345 -3.5.99.6 d-fructose 6-phosphate bos taurus 5.8 5.8 1 PMID:9774701 -3.5.99.6 d-fructose 6-phosphate escherichia coli 455.0 455.0 1 PMID:6375729 -3.5.99.6 d-fructose 6-phosphate thermococcus kodakarensis 44.2 44.2 1 PMID:16199574 -3.5.99.6 d-glucosamine 6-phosphate bacillus subtilis 8.0 8.0 1 PMID:15755726 -3.5.99.6 d-glucosamine 6-phosphate bos taurus 61.6 30.985 2 PMID:9774701 -3.5.99.6 d-glucosamine 6-phosphate canis lupus familiaris 255.0 148.5 2 PMID:1497340 -3.5.99.6 d-glucosamine 6-phosphate escherichia coli 1800.0 153.0 11 PMID:15667206;PMID:16168949;PMID:16285712;PMID:6375729;PMID:9601045 -3.5.99.6 d-glucosamine 6-phosphate homo sapiens 260.0 244.0 2 PMID:21807125 -3.5.99.6 d-glucosamine 6-phosphate thermococcus kodakarensis 97.5 97.5 1 PMID:16199574 -3.5.99.6 nh3 thermococcus kodakarensis 39.6 39.6 1 PMID:16199574 -3.5.99.7 1-aminocyclopropane-1-carboxylate amycolatopsis methanolica 0.085 0.085 1 * -3.5.99.7 1-aminocyclopropane-1-carboxylate methylobacterium nodulans 1.86 1.86 1 PMID:23517598 -3.5.99.7 1-aminocyclopropane-1-carboxylate methylobacterium radiotolerans 1.1 1.1 1 PMID:23517598 -3.5.99.7 1-aminocyclopropane-1-carboxylate pseudomonas putida 146.0 146.0 1 PMID:15588698 -3.5.99.7 1-aminocyclopropane-1-carboxylate pseudomonas sp. 4.83 4.83 1 PMID:7326243 -3.5.99.7 2-vinyl-1-aminocyclopropane-1-carboxylate pseudomonas sp. 5.17 5.17 1 PMID:7326243 -3.5.99.7 beta-chloro-d-alanine pectobacterium atrosepticum 0.532 0.532 1 * -3.5.99.7 d-cysteine pectobacterium atrosepticum 0.321 0.321 1 * -3.5.99.7 d-serine pectobacterium atrosepticum 0.267 0.267 1 * -3.5.99.7 d-vinylglycine pseudomonas sp. 0.6 0.6 1 PMID:7326243 -3.5.99.8 5-nitroanthranilate bradyrhizobium sp. js329 0.605 0.302 3 PMID:27694799 -3.6.1.1 adp pyrococcus furiosus 19.7 19.7 1 * -3.6.1.1 atp pyrococcus furiosus 91.7 91.7 1 * -3.6.1.1 atp saccharomyces cerevisiae 0.005 0.005 1 PMID:12169093 -3.6.1.1 cdp pyrococcus furiosus 51.3 51.3 1 * -3.6.1.1 ctp pyrococcus furiosus 94.2 94.2 1 * -3.6.1.1 diphosphate anabaena sp. 850.0 850.0 1 PMID:17635582 -3.6.1.1 diphosphate arabidopsis thaliana 12.1 11.9 3 PMID:31371393 -3.6.1.1 diphosphate bacteroides thetaiotaomicron 3.6 3.6 1 PMID:21894910 -3.6.1.1 diphosphate desulfitobacterium hafniense 320.0 225.0 5 PMID:27208172;PMID:30502330 -3.6.1.1 diphosphate escherichia coli 390.0 95.0 14 PMID:14640961;PMID:15701051;PMID:22984449;PMID:7827038 -3.6.1.1 diphosphate ethanoligenens harbinense 1850.0 1850.0 1 PMID:27208172 -3.6.1.1 diphosphate haloferax volcanii 1050.0 1050.0 1 PMID:26546423 -3.6.1.1 diphosphate helicobacter pylori 343.9 343.9 1 PMID:17598086 -3.6.1.1 diphosphate leishmania major 3693.0 2031.0 2 PMID:14988016 -3.6.1.1 diphosphate medicago truncatula 10.8 10.8 1 PMID:31371393 -3.6.1.1 diphosphate neomoorella thermoacetica 1.64 1.64 1 PMID:17714078 -3.6.1.1 diphosphate plasmodium falciparum 266.0 266.0 1 PMID:28701714 -3.6.1.1 diphosphate pseudanabaena sp. 850.0 850.0 1 PMID:17635582 -3.6.1.1 diphosphate pyrococcus furiosus 1230.0 1230.0 1 * -3.6.1.1 diphosphate pyrococcus horikoshii 3436.0 2090.0 2 PMID:16243777;PMID:24755063 -3.6.1.1 diphosphate saccharomyces cerevisiae 260.0 260.0 1 PMID:12169093 -3.6.1.1 diphosphate streptococcus gordonii 6290.0 6290.0 2 PMID:16829218;PMID:21450519 -3.6.1.1 diphosphate sulfolobus acidocaldarius 1700.0 1700.0 1 PMID:10049508 -3.6.1.1 diphosphate synechocystis sp. 916.0 858.0 2 PMID:17635582 -3.6.1.1 diphosphate thermococcus onnurineus 29950.0 0.22 5 PMID:19286799;PMID:19744243;PMID:36361526 -3.6.1.1 diphosphate thermoplasma acidophilum 2200.0 2200.0 1 PMID:1327774 -3.6.1.1 diphosphate trypanosoma cruzi 0.22 0.22 1 PMID:24033456 -3.6.1.1 diphosphate vibrio cholerae serotype o1 1600.0 101.0 6 PMID:17009951;PMID:19747093 -3.6.1.1 gdp pyrococcus furiosus 39.9 39.9 1 * -3.6.1.1 gtp pyrococcus furiosus 91.7 91.7 1 * -3.6.1.1 guanosine 5'-tetraphosphate trypanosoma cruzi 0.0022 0.0022 1 PMID:24033456 -3.6.1.1 idp pyrococcus furiosus 57.3 57.3 1 * -3.6.1.1 imidodiphosphoric acid bacillus subtilis 0.014 0.014 1 PMID:17095506 -3.6.1.1 itp pyrococcus furiosus 116.0 116.0 1 * -3.6.1.1 polyphosphate 75 trypanosoma cruzi 0.000165 0.000165 1 PMID:24033456 -3.6.1.1 triphosphate escherichia coli 16.7 16.7 1 PMID:22984449 -3.6.1.1 triphosphate pyrococcus furiosus 226.0 226.0 1 * -3.6.1.1 triphosphate trypanosoma cruzi 0.13 0.13 1 PMID:24033456 -3.6.1.1 tripolyphosphate saccharomyces cerevisiae 0.05 0.05 1 PMID:12169093 -3.6.1.1 udp pyrococcus furiosus 27.5 27.5 1 * -3.6.1.1 udp-glucose pyrococcus furiosus 29.7 29.7 1 * -3.6.1.1 utp pyrococcus furiosus 99.1 99.1 1 * -3.6.1.10 polyphosphate60 trypanosoma brucei 413625.0 413625.0 1 PMID:31043451 -3.6.1.10 polyphosphate700 trypanosoma brucei 73628.0 73628.0 1 PMID:31043451 -3.6.1.11 (phosphate)13-18 chlorobaculum tepidum 458.0 307.5 2 PMID:24969471 -3.6.1.11 (phosphate)25 homo sapiens 0.16 0.16 1 PMID:18700747 -3.6.1.11 (phosphate)3 chlorobaculum tepidum 399.0 206.25 2 PMID:24969471 -3.6.1.11 (phosphate)3 homo sapiens 35.0 24.0 2 PMID:18700747 -3.6.1.11 (phosphate)4 homo sapiens 7.1 5.25 2 PMID:18700747 -3.6.1.11 (phosphate)45 homo sapiens 0.22 0.22 1 PMID:18700747 -3.6.1.11 (phosphate)65 homo sapiens 0.03 0.03 1 PMID:18700747 -3.6.1.11 (phosphate)n saccharomyces cerevisiae 1550.0 1550.0 1 PMID:17599355 -3.6.1.11 (polyphosphate)130 mycobacterium tuberculosis 6.7 6.7 1 PMID:22880033 -3.6.1.11 (polyphosphate)14 mycobacterium tuberculosis 10.2 10.2 1 PMID:22880033 -3.6.1.11 (polyphosphate)60 mycobacterium tuberculosis 7.3 7.3 1 PMID:22880033 -3.6.1.11 (polyphosphate)n escherichia coli 0.05 0.05 1 PMID:15489502 -3.6.1.11 3'-amp escherichia coli 9.84 9.84 1 PMID:15489502 -3.6.1.11 3'-cmp escherichia coli 5.93 5.93 1 PMID:15489502 -3.6.1.11 5'-amp escherichia coli 4.9 4.9 1 PMID:15489502 -3.6.1.11 5'-dgmp escherichia coli 8.04 8.04 1 PMID:15489502 -3.6.1.11 5'-gmp escherichia coli 11.0 11.0 1 PMID:15489502 -3.6.1.11 adenosine 5'-tetraphosphate homo sapiens 39.0 35.0 2 PMID:18700747 -3.6.1.11 adenosine 5'-tetraphosphate saccharomyces cerevisiae 723.0 723.0 1 PMID:9565693 -3.6.1.11 adenosine-5'-pentaphosphate saccharomyces cerevisiae 40.0 40.0 1 PMID:9565693 -3.6.1.11 adp trypanosoma brucei brucei 12.555 12.555 1 PMID:31043451 -3.6.1.11 atp trypanosoma brucei brucei 22.649 22.649 1 PMID:31043451 -3.6.1.11 guanosine 5'-tetraphosphate chlorobaculum tepidum 308.0 161.1 2 PMID:24969471 -3.6.1.11 guanosine 5'-tetraphosphate homo sapiens 27.0 25.5 2 PMID:18700747 -3.6.1.11 guanosine 5'-tetraphosphate trypanosoma cruzi 0.7 0.7 1 PMID:17827150 -3.6.1.11 p-nitrophenyl phosphate escherichia coli 3.55 3.55 1 PMID:15489502 -3.6.1.11 pentasodium triphosphate trypanosoma brucei 8.1 8.1 1 PMID:21208463 -3.6.1.11 polyp10 saccharomyces cerevisiae 63.0 63.0 1 PMID:8157625 -3.6.1.11 polyp100 saccharomyces cerevisiae 3.3 3.3 1 PMID:8157625 -3.6.1.11 polyp25 saccharomyces cerevisiae 15.0 15.0 1 PMID:8157625 -3.6.1.11 polyp250 saccharomyces cerevisiae 1.2 1.2 1 PMID:8157625 -3.6.1.11 polyp33-36 saccharomyces cerevisiae 81.0 81.0 1 PMID:8071344 -3.6.1.11 polyp50 saccharomyces cerevisiae 8.4 8.4 1 PMID:8157625 -3.6.1.11 polyp500 saccharomyces cerevisiae 1.0 1.0 1 PMID:8157625 -3.6.1.11 polyp60-70 myxococcus xanthus 7.083 4.0205 2 PMID:33857634 -3.6.1.11 polyp700-1000 myxococcus xanthus 5.917 3.42 2 PMID:33857634 -3.6.1.11 polyp9-10 saccharomyces cerevisiae 90.0 90.0 1 PMID:8071344 -3.6.1.11 polyphosphate saccharomyces cerevisiae 1150.0 1150.0 1 PMID:17215253 -3.6.1.11 polyphosphate25 pseudomonas aeruginosa 40.2 23.73 2 PMID:26576296 -3.6.1.11 polyphosphate45 pseudomonas aeruginosa 41.23 23.259999999999998 2 PMID:26576296 -3.6.1.11 polyphosphate60 trypanosoma brucei brucei 44.11 36.03 2 PMID:31043451 -3.6.1.11 polyphosphate65 pseudomonas aeruginosa 53.03 29.945 2 PMID:26576296 -3.6.1.11 polyphosphate700 trypanosoma brucei brucei 16.39 9.451 2 PMID:31043451 -3.6.1.11 polyphosphate75 pseudomonas aeruginosa 57.02 31.855 2 PMID:26576296 -3.6.1.11 tetraphosphate corynebacterium glutamicum 0.9 0.9 1 PMID:19304823 -3.6.1.11 tetraphosphate homo sapiens 4.2 4.2 1 PMID:33105479 -3.6.1.11 tetraphosphate myxococcus xanthus 5.25 2.746 2 PMID:33857634 -3.6.1.11 triphosphate corynebacterium glutamicum 0.6 0.6 1 PMID:19304823 -3.6.1.11 triphosphate homo sapiens 6.24 6.24 1 PMID:33105479 -3.6.1.11 triphosphate myxococcus xanthus 5.75 0.705 3 PMID:33857634 -3.6.1.11 triphosphate trypanosoma cruzi 3.46 3.46 1 PMID:17827150 -3.6.1.11 tripolyphosphate saccharomyces cerevisiae 180.0 161.5 2 PMID:8071344;PMID:8157625 -3.6.1.12 2-chloro-datp mus musculus 1.57 1.57 1 PMID:19220460 -3.6.1.12 2-hydroxy-datp mus musculus 1.39 1.39 1 PMID:19220460 -3.6.1.12 5-bromo-dctp homo sapiens 9.3 4.902500000000001 2 PMID:24467396;PMID:26075750 -3.6.1.12 5-bromo-dctp mus musculus 1.49 1.49 1 PMID:19220460 -3.6.1.12 5-chloro-dctp mus musculus 1.5 1.5 1 PMID:19220460 -3.6.1.12 5-fluoro-dutp mus musculus 0.58 0.58 1 PMID:19220460 -3.6.1.12 5-formyl-dctp homo sapiens 3.0 3.0 1 PMID:24467396 -3.6.1.12 5-hydroxy-dctp mus musculus 0.87 0.87 1 PMID:19220460 -3.6.1.12 5-hydroxymethyl-dctp homo sapiens 5.6 5.6 1 PMID:24467396 -3.6.1.12 5-iodo-dctp homo sapiens 6.2 0.43 3 PMID:21671327;PMID:24467396;PMID:26075750 -3.6.1.12 5-iodo-dctp mus musculus 0.94 0.94 1 PMID:19220460 -3.6.1.12 5-methyl-dctp homo sapiens 4.8 2.581 2 PMID:24467396;PMID:26075750 -3.6.1.12 5-methyl-dctp mus musculus 1.33 0.08 3 PMID:19220460;PMID:31954130 -3.6.1.12 ctp mus musculus 0.31 0.31 1 PMID:19220460 -3.6.1.12 datp homo sapiens 2.0 1.07 2 PMID:24467396;PMID:26075750 -3.6.1.12 datp mus musculus 0.53 0.53 1 PMID:19220460 -3.6.1.12 dctp homo sapiens 5.7 3.0335 2 PMID:24467396;PMID:26075750 -3.6.1.12 dctp mus musculus 1.37 0.13 3 PMID:19220460;PMID:31954130 -3.6.1.12 dttp homo sapiens 1.8 0.9540000000000001 2 PMID:24467396;PMID:26075750 -3.6.1.12 dttp mus musculus 0.76 0.76 1 PMID:19220460 -3.6.1.12 dutp homo sapiens 0.081 0.081 1 PMID:26075750 -3.6.1.12 dutp mus musculus 0.76 0.76 1 PMID:19220460 -3.6.1.13 2''-o-acetyl-adp-ribose mus musculus 0.78 0.78 1 PMID:12370179 -3.6.1.13 2',3'-camp danio rerio 16.9 16.9 1 PMID:22848751 -3.6.1.13 2',3'-camp homo sapiens 60.0 60.0 1 PMID:25692488 -3.6.1.13 adp danio rerio 1.8 1.8 1 PMID:22848751 -3.6.1.13 adp-d-ribose homo sapiens 11.8 11.8 1 PMID:18462755 -3.6.1.13 adp-d-ribose mus musculus 0.94 0.94 1 PMID:12370179 -3.6.1.13 adp-glucose thermus thermophilus 9.1 9.1 1 PMID:15981998 -3.6.1.13 adp-ribose arabidopsis thaliana 0.12 0.11499999999999999 4 PMID:15878881 -3.6.1.13 adp-ribose autographa californica multiple nucleopolyhedrovirus 6.96 6.96 1 PMID:17174373 -3.6.1.13 adp-ribose danio rerio 18.0 18.0 1 PMID:22848751 -3.6.1.13 adp-ribose homo sapiens 35.0 11.4 3 PMID:10567213;PMID:18462755;PMID:25692488 -3.6.1.13 adp-ribose synechocystis sp. 20.0 8.6 3 PMID:15995214 -3.6.1.13 adp-ribose thermus thermophilus 10.65 5.300000000000001 6 PMID:15210687;PMID:15981998;PMID:18039767 -3.6.1.13 adpribose bacillus subtilis 64.8 64.8 1 PMID:10542272 -3.6.1.13 adpribose escherichia coli 117.0 117.0 1 PMID:10542272 -3.6.1.13 adpribose haemophilus influenzae 9.2 9.2 1 PMID:10542272 -3.6.1.13 adpribose homo sapiens 8.0 8.0 1 PMID:11825615 -3.6.1.13 adpribose methanocaldococcus jannaschii 1.98 1.94 2 PMID:10542272;PMID:9694840 -3.6.1.13 adpribose saccharomyces cerevisiae 7.92 7.92 1 PMID:10542272 -3.6.1.13 adpribose synechococcus sp. 1.8 1.8 1 PMID:15158734 -3.6.1.13 adpribose 2'-phosphate methanocaldococcus jannaschii 1.14 1.14 1 PMID:9694840 -3.6.1.13 cadp-ribose danio rerio 0.0005 0.0005 1 PMID:22848751 -3.6.1.13 cadp-ribose homo sapiens 3.2 3.2 1 PMID:25692488 -3.6.1.13 cdp-choline danio rerio 67.2 67.2 1 PMID:22848751 -3.6.1.13 cdp-choline homo sapiens 50.0 50.0 1 PMID:25692488 -3.6.1.13 cdp-ethanolamine danio rerio 125.2 125.2 1 PMID:22848751 -3.6.1.13 cdp-glycerol danio rerio 95.6 95.6 1 PMID:22848751 -3.6.1.13 cdp-ribose thermus thermophilus 3.36 3.36 1 PMID:15981998 -3.6.1.13 fad thermus thermophilus 5.0 3.75 2 PMID:18039767 -3.6.1.13 gdp-ribose thermus thermophilus 3.57 3.57 1 PMID:15981998 -3.6.1.14 adenosine 5'-tetraphosphate saccharomyces cerevisiae 723.0 723.0 1 PMID:9565693 -3.6.1.14 adenosine-5'-pentaphosphate saccharomyces cerevisiae 40.0 40.0 1 PMID:9565693 -3.6.1.15 adp deinococcus radiodurans 0.29 0.29 1 PMID:18512963 -3.6.1.15 adp homo sapiens 0.0051 0.0051 1 PMID:17291528 -3.6.1.15 atp classical swine fever virus 4384.0 2269.5 2 PMID:17447110 -3.6.1.15 atp deinococcus radiodurans 0.29 0.29 1 PMID:18512963 -3.6.1.15 atp homo sapiens 0.0086 0.0086 1 PMID:17291528 -3.6.1.15 atp mammalian orthoreovirus 13.8 13.8 1 PMID:14613938 -3.6.1.15 atp saccharomyces cerevisiae 10.25 5.59 2 PMID:16008364 -3.6.1.15 atp southampton virus 1.4 1.4 1 PMID:11160659 -3.6.1.15 atp staphylococcus aureus 4.45 0.567 3 PMID:33955674 -3.6.1.15 atp streptomyces coelicolor 0.1333 0.1333 1 PMID:33955674 -3.6.1.15 atp west nile virus 133.0 133.0 1 PMID:11238848 -3.6.1.15 cdp deinococcus radiodurans 1.67 1.67 1 PMID:18512963 -3.6.1.15 ctp classical swine fever virus 2286.0 1253.0 2 PMID:17447110 -3.6.1.15 ctp deinococcus radiodurans 0.59 0.59 1 PMID:18512963 -3.6.1.15 ctp homo sapiens 0.0073 0.0073 1 PMID:17291528 -3.6.1.15 ctp mammalian orthoreovirus 8.0 8.0 1 PMID:14613938 -3.6.1.15 ctp saccharomyces cerevisiae 16.67 8.82 2 PMID:16008364 -3.6.1.15 dadp deinococcus radiodurans 0.52 0.52 1 PMID:18512963 -3.6.1.15 datp classical swine fever virus 3150.0 1679.0 2 PMID:17447110 -3.6.1.15 datp deinococcus radiodurans 0.31 0.31 1 PMID:18512963 -3.6.1.15 datp saccharomyces cerevisiae 11.18 5.915 2 PMID:16008364 -3.6.1.15 dcdp deinococcus radiodurans 1.12 1.12 1 PMID:18512963 -3.6.1.15 dctp classical swine fever virus 5096.0 2615.5 2 PMID:17447110 -3.6.1.15 dctp deinococcus radiodurans 0.3 0.3 1 PMID:18512963 -3.6.1.15 dctp saccharomyces cerevisiae 12.57 6.535 2 PMID:16008364 -3.6.1.15 dgdp deinococcus radiodurans 0.51 0.51 1 PMID:18512963 -3.6.1.15 dgtp classical swine fever virus 2500.0 1318.0 2 PMID:17447110 -3.6.1.15 dgtp deinococcus radiodurans 0.4 0.4 1 PMID:18512963 -3.6.1.15 dgtp saccharomyces cerevisiae 10.2 10.2 1 PMID:16008364 -3.6.1.15 ditp deinococcus radiodurans 0.22 0.22 1 PMID:18512963 -3.6.1.15 dttp saccharomyces cerevisiae 10.9 10.9 1 PMID:16008364 -3.6.1.15 dutp classical swine fever virus 1875.0 978.5 2 PMID:17447110 -3.6.1.15 gdp deinococcus radiodurans 0.39 0.39 1 PMID:18512963 -3.6.1.15 gtp classical swine fever virus 2963.0 1681.5 2 PMID:17447110 -3.6.1.15 gtp deinococcus radiodurans 0.32 0.32 1 PMID:18512963 -3.6.1.15 gtp homo sapiens 0.0076 0.0076 1 PMID:17291528 -3.6.1.15 gtp mammalian orthoreovirus 9.8 9.8 1 PMID:14613938 -3.6.1.15 gtp saccharomyces cerevisiae 9.03 5.5 2 PMID:16008364 -3.6.1.15 gtp staphylococcus aureus 1.733 1.733 1 PMID:33955674 -3.6.1.15 idp deinococcus radiodurans 0.06 0.06 1 PMID:18512963 -3.6.1.15 itp deinococcus radiodurans 0.18 0.18 1 PMID:18512963 -3.6.1.15 rna mammalian orthoreovirus 0.005 0.005 1 PMID:14613938 -3.6.1.15 tdp deinococcus radiodurans 1.03 1.03 1 PMID:18512963 -3.6.1.15 ttp deinococcus radiodurans 0.69 0.69 1 PMID:18512963 -3.6.1.15 ttp homo sapiens 0.0074 0.0074 1 PMID:17291528 -3.6.1.15 udp deinococcus radiodurans 1.35 1.35 1 PMID:18512963 -3.6.1.15 utp classical swine fever virus 2162.0 1138.0 2 PMID:17447110 -3.6.1.15 utp deinococcus radiodurans 0.53 0.53 1 PMID:18512963 -3.6.1.15 utp homo sapiens 0.007 0.007 1 PMID:17291528 -3.6.1.15 utp mammalian orthoreovirus 7.3 7.3 1 PMID:14613938 -3.6.1.15 utp saccharomyces cerevisiae 17.28 9.125 2 PMID:16008364 -3.6.1.17 2-oxo-datp caenorhabditis elegans 0.51 0.51 1 PMID:21111690 -3.6.1.17 5',5''-diadenosine tetraphosphate plasmodium falciparum 0.042 0.042 1 PMID:22791172 -3.6.1.17 5',5'-diadenosine hexaphosphate drosophila melanogaster 4.0 4.0 1 PMID:17344088 -3.6.1.17 5',5'-diadenosine tetraphosphate drosophila melanogaster 43.0 28.0 2 PMID:17344088 -3.6.1.17 8-oxo-dgtp caenorhabditis elegans 0.58 0.58 1 PMID:21111690 -3.6.1.17 ap4a caenorhabditis elegans 27.0 25.0 2 PMID:11738085;PMID:12475970 -3.6.1.17 ap4a lupinus angustifolius 40.8 40.8 1 PMID:11439089 -3.6.1.17 datp caenorhabditis elegans 0.37 0.37 1 PMID:21111690 -3.6.1.17 dgtp caenorhabditis elegans 0.53 0.53 1 PMID:21111690 -3.6.1.17 diadenosine 5',5''''-p1,p4-tetraphosphate caenorhabditis elegans 27.0 27.0 1 PMID:21111690 -3.6.1.17 diadenosine 5',5''-p1,p4-tetraphosphate chlamydia trachomatis 3.25 1.69 6 PMID:24354275 -3.6.1.17 p1,p4-bis(5'-adenosyl) tetraphosphate aquifex aeolicus 2.5 2.5 1 PMID:20124691 -3.6.1.17 p1,p4-bis(5'-adenosyl) tetraphosphate photinus pyralis 3.6 3.6 1 PMID:7876110 -3.6.1.17 p1,p4-bis(5'-adenosyl)tetraphosphate myxococcus xanthus 0.055 0.055 1 PMID:25107648 -3.6.1.17 p1,p5-bis(5'-adenosyl) pentaphosphate aquifex aeolicus 1.4 1.4 1 PMID:20124691 -3.6.1.17 p1,p5-bis(5'-adenosyl)pentaphosphate myxococcus xanthus 0.035 0.035 1 PMID:25107648 -3.6.1.17 p1,p6-bis(5'-adenosyl) hexaphosphate aquifex aeolicus 0.2 0.2 1 PMID:20124691 -3.6.1.18 fad chlamydomonas reinhardtii 0.395 0.395 1 PMID:36273586 -3.6.1.22 nad+ caenorhabditis elegans 0.000167 0.000167 1 PMID:10873676 -3.6.1.22 nad+ escherichia coli 19.3 19.3 1 PMID:24731828 -3.6.1.22 nad+ saccharomyces cerevisiae 0.000167 0.000167 1 PMID:10873676 -3.6.1.22 nadh caenorhabditis elegans 0.00117 0.00117 1 PMID:10873676 -3.6.1.22 nadh escherichia coli 59.5 10.0 3 PMID:24731828;PMID:37082214;PMID:7829480 -3.6.1.22 nadh saccharomyces cerevisiae 0.0025 0.0025 1 PMID:10873676 -3.6.1.22 nmn escherichia coli 1492.0 1492.0 1 PMID:24731828 -3.6.1.23 datp dugesia ryukyuensis 1.5 1.5 1 PMID:30902068 -3.6.1.23 datp leishmania major 5.4 5.4 1 PMID:11420444 -3.6.1.23 dctp drosophila melanogaster 0.7 0.7 1 PMID:14724274 -3.6.1.23 dctp dugesia ryukyuensis 1.6 1.6 1 PMID:30902068 -3.6.1.23 dctp leishmania major 13.0 13.0 1 PMID:11420444 -3.6.1.23 dgtp dugesia ryukyuensis 2.9 2.9 1 PMID:30902068 -3.6.1.23 dgtp leishmania major 6.4 6.4 1 PMID:11420444 -3.6.1.23 ditp saccharomyces cerevisiae 1.3 1.3 1 PMID:21548881 -3.6.1.23 dttp drosophila melanogaster 0.1 0.1 1 PMID:14724274 -3.6.1.23 dttp dugesia ryukyuensis 1.4 1.4 1 PMID:30902068 -3.6.1.23 dttp leishmania major 8.6 8.6 1 PMID:11420444 -3.6.1.23 dudp leishmania major 65.0 65.0 1 PMID:11420444 -3.6.1.23 dutp african swine fever virus 4.37 4.37 1 PMID:33139328 -3.6.1.23 dutp aquifex aeolicus 3.0 2.65 2 PMID:39440877 -3.6.1.23 dutp campylobacter jejuni 12.3 12.3 1 PMID:18608754 -3.6.1.23 dutp dictyostelium discoideum 9.3 6.300000000000001 2 PMID:31910901 -3.6.1.23 dutp drosophila melanogaster 12.0 12.0 1 PMID:14724274 -3.6.1.23 dutp drosophila virilis 4.7 4.7 1 PMID:27380921 -3.6.1.23 dutp dugesia ryukyuensis 48.0 41.0 2 PMID:30902068 -3.6.1.23 dutp equine infectious anemia virus 25.0 25.0 1 PMID:9315700 -3.6.1.23 dutp escherichia coli 58.3 12.85 10 PMID:12721364;PMID:15208312;PMID:18597482;PMID:29187596;PMID:346589;PMID:8798636 -3.6.1.23 dutp homo sapiens 9.17 6.58 3 PMID:17848562;PMID:20601405;PMID:6143756 -3.6.1.23 dutp human alphaherpesvirus 1 15.0 15.0 1 PMID:9883909 -3.6.1.23 dutp human gammaherpesvirus 4 3.3 1.5 4 PMID:19586911 -3.6.1.23 dutp leishmania major 49.0 49.0 1 PMID:11420444 -3.6.1.23 dutp mycobacterium tuberculosis 3.0 2.11 2 PMID:22655049;PMID:27740761 -3.6.1.23 dutp paramecium bursaria chlorella virus 1 6.8 6.8 1 PMID:16014955 -3.6.1.23 dutp plasmodium falciparum 11.67 7.535 2 PMID:18586121;PMID:21600680 -3.6.1.23 dutp saccharomyces cerevisiae 9.6 9.6 1 PMID:21548881 -3.6.1.23 dutp spbetavirus spbeta 18.0 18.0 1 PMID:15939294 -3.6.1.23 dutp sus scrofa 5.58 5.58 1 PMID:33139328 -3.6.1.23 dutp thermococcus pacificus 4.2 3.55 2 PMID:39440877 -3.6.1.23 dutp trypanosoma brucei 9.7 9.7 1 PMID:18656547 -3.6.1.23 dutp trypanosoma cruzi 2.8 2.8 1 PMID:12208522 -3.6.1.23 dutp white spot syndrome virus 7.4 7.4 1 PMID:29187596 -3.6.1.23 dutp-co2+ plasmodium falciparum 4.1 4.1 1 PMID:18586121 -3.6.1.23 dutp-mg2+ plasmodium falciparum 13.3 13.3 1 PMID:18586121 -3.6.1.23 dutp-mn2+ plasmodium falciparum 5.3 5.3 1 PMID:18586121 -3.6.1.25 atp nitrosomonas europaea 0.36 0.36 1 PMID:21840996 -3.6.1.25 triphosphate sulfolobus acidocaldarius 5934.0 5934.0 1 PMID:34029589 -3.6.1.25 tripolyphosphate nitrosomonas europaea 7900.0 182.0 4 PMID:21840996 -3.6.1.27 diacylglycerol diphosphate escherichia coli 280.0 280.0 1 PMID:18411271 -3.6.1.27 diphosphate escherichia coli 48.0 48.0 1 PMID:18411271 -3.6.1.27 farnesyl diphosphate escherichia coli 290.0 146.05 2 PMID:18411271;PMID:24855653 -3.6.1.27 farnesyl diphosphate vibrio vulnificus 2.3 2.3 1 PMID:28302513 -3.6.1.27 isopentenyl diphosphate escherichia coli 19.0 19.0 1 PMID:18411271 -3.6.1.27 phosphatidic acid escherichia coli 61.0 61.0 1 PMID:18411271 -3.6.1.27 undecaprenyl diphosphate escherichia coli 27.0 18.0 2 PMID:18411271;PMID:26560897 -3.6.1.28 atp homo sapiens 0.24 0.24 1 PMID:15109578 -3.6.1.28 thiamine triphosphate bos taurus 240.0 240.0 1 PMID:11827967 -3.6.1.28 thiamine triphosphate homo sapiens 240.0 190.0 2 PMID:11827967;PMID:15109578 -3.6.1.28 thiamine triphosphate mus musculus 23.0 23.0 1 PMID:23707715 -3.6.1.29 5'-o-[amino(hydroxy)phosphoryl]adenosine arabidopsis thaliana 1.26 1.26 1 PMID:18694747 -3.6.1.29 adenosine 5'-phosphoramidate homo sapiens 1.26 1.26 1 PMID:18694747 -3.6.1.29 adenosine-5'-phospho-n-methylimidazolide homo sapiens 4.2 4.2 1 PMID:15182206 -3.6.1.29 adenosine-5'-phosphoimidazolide homo sapiens 4.4 4.4 1 PMID:15182206 -3.6.1.29 ap4a homo sapiens 0.53 0.495 2 PMID:32445636 -3.6.1.29 p1,p3-bis(5'-adenosyl)triphosphate homo sapiens 6.0 1.56 4 PMID:15835917 -3.6.1.29 p1-5'-o-adenosine-p3-5'-o-adenosine triphosphate homo sapiens 3.5 3.5 1 PMID:15182206 -3.6.1.31 1-(5-phospho-beta-d-ribosyl)-atp acinetobacter baumannii 9.6 5.6 3 PMID:37288093 -3.6.1.39 dttp escherichia phage t7 20.0 10.11 2 PMID:21566126 -3.6.1.40 guanosine 5'-triphosphate 3'-diphosphate escherichia coli 14.406 14.406 1 PMID:31679177 -3.6.1.40 guanosine 5'-triphosphate 3'-diphosphate helicobacter pylori 0.044 0.044 1 PMID:31679177 -3.6.1.40 guanosine 5'-triphosphate,3'-diphosphate escherichia coli 0.023 0.023 1 PMID:8394006 -3.6.1.40 polyphosphate escherichia coli 1.1 1.1 1 PMID:8394006 -3.6.1.41 ap4a staphylococcus aureus 107.0 107.0 1 PMID:32152217 -3.6.1.41 ap4a streptococcus pneumoniae 222.6 222.6 1 PMID:38701795 -3.6.1.41 ap4g staphylococcus aureus 210.0 210.0 1 PMID:32152217 -3.6.1.41 ap4u staphylococcus aureus 324.0 324.0 1 PMID:32152217 -3.6.1.41 ap5a staphylococcus aureus 32.0 32.0 1 PMID:32152217 -3.6.1.41 ap5a streptococcus pneumoniae 82.1 82.1 1 PMID:38701795 -3.6.1.41 atp streptococcus pneumoniae 0.08 0.08 1 PMID:38701795 -3.6.1.41 ctp streptococcus pneumoniae 0.065 0.065 1 PMID:38701795 -3.6.1.41 gp4g staphylococcus aureus 1002.0 1002.0 1 PMID:32152217 -3.6.1.41 gtp streptococcus pneumoniae 0.08 0.08 1 PMID:38701795 -3.6.1.41 p1,p4-bis(5'-adenosyl) tetraphosphate escherichia coli 250.0 250.0 1 PMID:2986688 -3.6.1.41 p1,p4-bis(adenosyl)tetraphosphate myxococcus xanthus 7.12 3.5875 2 PMID:25107648 -3.6.1.41 p1,p5-bis(adenosyl)pentaphosphate myxococcus xanthus 24.0 12.0175 2 PMID:25107648 -3.6.1.41 utp streptococcus pneumoniae 0.067 0.067 1 PMID:38701795 -3.6.1.42 gdp saccharomyces cerevisiae 3830.0 3830.0 1 PMID:2172253 -3.6.1.45 amp escherichia coli 405.0 405.0 1 PMID:24731828 -3.6.1.45 nad+ escherichia coli 19.3 19.3 1 PMID:24731828 -3.6.1.45 nadh escherichia coli 10.0 10.0 1 PMID:24731828 -3.6.1.45 nmn escherichia coli 1492.0 1492.0 1 PMID:24731828 -3.6.1.45 udp-d-glucose escherichia coli 0.2 0.15000000000000002 2 PMID:33923386 -3.6.1.45 udp-glucose escherichia coli 71.0 71.0 1 PMID:18641143 -3.6.1.45 udp-glucose yersinia intermedia 97.0 97.0 1 PMID:18641143 -3.6.1.5 1,n6-etheno-adp solanum tuberosum 1384.0 735.0 2 PMID:15896365 -3.6.1.5 1,n6-etheno-atp solanum tuberosum 1642.0 1162.0 2 PMID:15896365 -3.6.1.5 2'(3')-o-(2,4,6-trinitrophenyl)adenosine 5'-diphosphate solanum tuberosum 328.0 199.0 2 PMID:15896365 -3.6.1.5 2'(3')-o-(2,4,6-trinitrophenyl)adenosine 5'-triphosphate solanum tuberosum 982.0 586.5 2 PMID:15896365 -3.6.1.5 3'(2')-o-(methylanthranoyl)adenosine 5'-diphosphate solanum tuberosum 828.0 425.5 2 PMID:15896365 -3.6.1.5 3'(2')-o-(methylanthranoyl)adenosine 5'-triphosphate solanum tuberosum 965.0 882.5 2 PMID:15896365 -3.6.1.5 8-oxo-dgtp bacillus subtilis 0.96 0.96 1 PMID:15576788 -3.6.1.5 adp daboia russelii 248.6 248.6 1 PMID:29325746 -3.6.1.5 adp rattus norvegicus 77.3 77.3 1 PMID:22100451 -3.6.1.5 ampcpp rattus norvegicus 40.5 40.5 1 PMID:22100451 -3.6.1.5 atp daboia russelii 410.0 410.0 1 PMID:29325746 -3.6.1.5 atp heligmosomoides polygyrus bakeri 28.33 12.08335 4 PMID:32931780 -3.6.1.5 atp homo sapiens 63.1 63.1 1 PMID:36396461 -3.6.1.5 atp solanum tuberosum 100.0 100.0 1 PMID:27821623 -3.6.1.5 atp sus scrofa 860.0 860.0 1 PMID:12899702 -3.6.1.5 atp toxoplasma gondii 280.0 280.0 1 PMID:24115522 -3.6.1.5 datp bacillus subtilis 1.5 1.5 1 PMID:15576788 -3.6.1.5 datp solanum tuberosum 2222.0 1429.0 2 PMID:15896365 -3.6.1.5 dctp homo sapiens 4.27 4.27 1 PMID:38331874 -3.6.1.5 dctp solanum tuberosum 2174.0 1332.0 2 PMID:15896365 -3.6.1.5 dgtp bacillus subtilis 0.74 0.74 1 PMID:15576788 -3.6.1.5 dgtp solanum tuberosum 3019.0 1796.0 2 PMID:15896365 -3.6.1.5 dttp solanum tuberosum 2841.0 1648.0 2 PMID:15896365 -3.6.1.5 emtricitabine triphosphate homo sapiens 3.383 3.383 1 PMID:38331874 -3.6.1.5 gdp rattus norvegicus 103.7 83.2 4 PMID:22100451 -3.6.1.5 gemcitabine triphosphate homo sapiens 3.428 3.428 1 PMID:38331874 -3.6.1.5 gtp rattus norvegicus 80.9 80.9 1 PMID:22100451 -3.6.1.5 idp rattus norvegicus 79.9 79.9 1 PMID:22100451 -3.6.1.5 itp rattus norvegicus 105.3 105.3 1 PMID:22100451 -3.6.1.5 n-[5-[4-carboxy-3-(3-oxo-9,9a-dihydro-3h-xanthen-9-yl)benzamido]pentyl]adenosine 5'-triphosphate homo sapiens 0.119 0.04405 4 PMID:30303204 -3.6.1.5 tdp rattus norvegicus 80.2 80.2 1 PMID:22100451 -3.6.1.5 tenofovir-diphosphate homo sapiens 64.1 64.1 1 PMID:36396461 -3.6.1.5 thio-datp solanum tuberosum 1101.0 848.0 2 PMID:15896365 -3.6.1.5 udp rattus norvegicus 80.9 80.9 1 PMID:22100451 -3.6.1.5 utp rattus norvegicus 103.4 103.4 1 PMID:22100451 -3.6.1.52 1,5-bis-diphosphoinositol 2,3,4,6-tetrakisphosphate homo sapiens 0.237 0.237 1 PMID:33475202 -3.6.1.52 1-diphosphoinositol 2,3,4,5,6-pentakisphosphate homo sapiens 0.165 0.165 1 PMID:33475202 -3.6.1.52 2-diphosphoinositol 1,3,4,5,6-pentakisphosphate homo sapiens 0.042 0.042 1 PMID:33475202 -3.6.1.52 4-diphosphoinositol 1,2,3,5,6-pentakisphosphate homo sapiens 0.029 0.029 1 PMID:33475202 -3.6.1.52 4-nitrophenyl phosphate saccharomyces cerevisiae 4.4e-07 4.4e-07 1 PMID:26828065 -3.6.1.52 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate homo sapiens 0.081 0.081 1 PMID:33475202 -3.6.1.52 5-diphosphoinositol 1,3,4,6-tetrakisphosphate homo sapiens 0.095 0.095 1 PMID:33475202 -3.6.1.52 5-diphosphoinositol pentakisphosphate saccharomyces cerevisiae 0.0025 0.0025 1 PMID:26828065 -3.6.1.52 5-phospho-d-ribosyl 1-diphosphate drosophila melanogaster 0.1 0.1 1 PMID:20394834 -3.6.1.52 adenosine tetraphosphate drosophila melanogaster 0.24 0.24 1 PMID:20394834 -3.6.1.52 diadenosine 5',5'''-p1,p6-hexaphosphate drosophila melanogaster 0.34 0.34 1 PMID:20394834 -3.6.1.52 diphosphoinositol pentakisphosphate drosophila melanogaster 0.024 0.024 1 PMID:20394834 -3.6.1.52 diphosphoinositol pentakisphosphate homo sapiens 0.2 0.15 3 PMID:10777568 -3.6.1.52 guanosine tetraphosphate drosophila melanogaster 0.8 0.8 1 PMID:20394834 -3.6.1.53 2',3'-camp danio rerio 16.9 16.9 1 PMID:22848751 -3.6.1.53 2',3'-camp homo sapiens 60.0 60.0 1 PMID:25692488 -3.6.1.53 adp danio rerio 1.8 1.8 1 PMID:22848751 -3.6.1.53 adp rattus norvegicus 4.4 4.4 2 PMID:18352857 -3.6.1.53 adp-ribose danio rerio 18.0 18.0 1 PMID:22848751 -3.6.1.53 adp-ribose homo sapiens 35.0 35.0 1 PMID:25692488 -3.6.1.53 adp-ribose rattus norvegicus 12.8 12.8 2 PMID:18352857 -3.6.1.53 cdp-choline danio rerio 67.2 67.2 1 PMID:22848751 -3.6.1.53 cdp-choline homo sapiens 50.0 50.0 1 PMID:25692488 -3.6.1.53 cdp-choline rattus norvegicus 28.5 28.5 2 PMID:18352857 -3.6.1.53 cdp-ethanolamine danio rerio 125.2 125.2 1 PMID:22848751 -3.6.1.53 cdp-ethanolamine rattus norvegicus 41.3 41.3 2 PMID:18352857 -3.6.1.53 cdp-glycerol danio rerio 95.6 95.6 1 PMID:22848751 -3.6.1.53 cdp-glycerol rattus norvegicus 28.1 28.1 2 PMID:18352857 -3.6.1.53 cyclic adp-ribose danio rerio 0.005 0.005 1 PMID:22848751 -3.6.1.53 cyclic adp-ribose homo sapiens 3.2 3.2 1 PMID:25692488 -3.6.1.53 cyclic adp-ribose rattus norvegicus 0.87 0.87 1 PMID:19379742 -3.6.1.55 8-oxo-dgtp ciona intestinalis 2.55 2.55 1 PMID:21178309 -3.6.1.55 8-oxo-dgtp homo sapiens 18.9 18.9 1 PMID:26879218 -3.6.1.56 2-hydroxy-atp homo sapiens 4.7 4.7 1 PMID:11139615 -3.6.1.56 2-hydroxy-datp homo sapiens 28.7 13.9 3 PMID:10373420;PMID:11139615;PMID:11756418 -3.6.1.56 2-hydroxy-datp myxococcus xanthus 0.097 0.097 2 PMID:31292314 -3.6.1.56 2-oxo-datp homo sapiens 21.1 21.1 1 PMID:28035004 -3.6.1.56 8-oxo-atp homo sapiens 1.1 1.1 1 PMID:11139615 -3.6.1.56 8-oxo-datp homo sapiens 10.8 10.8 1 PMID:10373420;PMID:11139615 -3.6.1.56 8-oxo-datp myxococcus xanthus 0.103 0.103 2 PMID:31292314 -3.6.1.56 8-oxo-dgdp myxococcus xanthus 0.273 0.273 2 PMID:31292314 -3.6.1.56 8-oxo-dgtp homo sapiens 25.9 16.5 4 PMID:10373420;PMID:11139615;PMID:11756418;PMID:28035004 -3.6.1.56 8-oxo-dgtp myxococcus xanthus 1.13 1.129 2 PMID:31292314 -3.6.1.56 8-oxo-gtp homo sapiens 2.6 2.6 1 PMID:11139615 -3.6.1.56 adp myxococcus xanthus 0.102 0.102 1 PMID:31292314 -3.6.1.56 ap4a myxococcus xanthus 0.103 0.103 1 PMID:31292314 -3.6.1.56 atp myxococcus xanthus 0.158 0.158 1 PMID:31292314 -3.6.1.56 dadp myxococcus xanthus 0.143 0.143 1 PMID:31292314 -3.6.1.56 datp myxococcus xanthus 0.15 0.15 1 PMID:31292314 -3.6.1.56 dgdp myxococcus xanthus 0.128 0.128 1 PMID:31292314 -3.6.1.56 dgtp homo sapiens 15.7 15.7 1 PMID:10373420;PMID:11139615 -3.6.1.56 dgtp myxococcus xanthus 0.308 0.308 1 PMID:31292314 -3.6.1.56 gdp myxococcus xanthus 0.187 0.187 1 PMID:31292314 -3.6.1.56 gtp myxococcus xanthus 0.338 0.338 1 PMID:31292314 -3.6.1.57 udp-2,4-diacetamido-2,4,6-trideoxy-beta-l-altropyranose campylobacter jejuni 26.6 25.8 2 PMID:16728396;PMID:19483088 -3.6.1.58 2-hydroxy-dadp homo sapiens 0.004 0.004 1 PMID:19699693 -3.6.1.58 5-formyl-dudp homo sapiens 0.0035 0.0035 1 PMID:19699693 -3.6.1.58 8-oxo-dadp homo sapiens 0.009 0.009 1 PMID:19699693 -3.6.1.58 8-oxo-dgdp homo sapiens 0.006 0.006 1 PMID:19699693 -3.6.1.58 dadp homo sapiens 0.006 0.006 1 PMID:19699693 -3.6.1.58 dgdp homo sapiens 0.015 0.015 1 PMID:19699693 -3.6.1.59 7-methylguanosine 5'-diphosphate saccharomyces cerevisiae 0.0017 0.0017 1 PMID:16963086 -3.6.1.59 m32,2,7gpppg ascaris suum 2.38 2.12 3 PMID:32455195 -3.6.1.59 m32,2,7gpppg caenorhabditis elegans 6.98 4.02 3 PMID:32455195 -3.6.1.59 m7g5'ppp5'g ascaris suum 1.85 1.55 3 PMID:32455195 -3.6.1.59 m7g5'ppp5'g caenorhabditis elegans 1.49 1.13 3 PMID:32455195 -3.6.1.59 m7g5'ppp5'g homo sapiens 0.56 0.39 3 PMID:32455195 -3.6.1.59 m7g5'ppp5'g saccharomyces cerevisiae 0.012 0.012 1 PMID:16963086 -3.6.1.6 adp staphylococcus aureus 2.3 1.3575 2 PMID:27422825;PMID:33955674 -3.6.1.6 adp streptomyces coelicolor 1.003 1.003 1 PMID:33955674 -3.6.1.6 adp toxoplasma gondii 238.0 238.0 1 PMID:24115522 -3.6.1.6 atp staphylococcus aureus 0.567 0.567 1 PMID:33955674 -3.6.1.6 atp streptomyces coelicolor 0.1333 0.1333 1 PMID:33955674 -3.6.1.6 cdp staphylococcus aureus 0.763 0.763 1 PMID:27422825 -3.6.1.6 gdp staphylococcus aureus 0.7 0.5285 2 PMID:27422825;PMID:33955674 -3.6.1.6 gdp streptomyces coelicolor 0.9 0.9 1 PMID:33955674 -3.6.1.6 gtp staphylococcus aureus 1.733 1.733 1 PMID:33955674 -3.6.1.6 tdp staphylococcus aureus 0.68 0.68 1 PMID:27422825 -3.6.1.6 udp staphylococcus aureus 1.388 1.388 1 PMID:27422825 -3.6.1.60 p1,p5-bis(5'-adenosyl)pentaphosphate homo sapiens 0.8 0.41000000000000003 4 PMID:10419486;PMID:12121577 -3.6.1.60 p1,p6-bis(5'-adenosyl)hexaphosphate arabidopsis thaliana 9.8 9.8 1 PMID:17824959 -3.6.1.60 p1,p6-bis(5'-adenosyl)hexaphosphate homo sapiens 0.5 0.185 4 PMID:10419486;PMID:12121577 -3.6.1.61 p1,p4-bis(5'-adenosyl)tetraphosphate escherichia coli 0.1 0.1 1 PMID:11479323 -3.6.1.61 p1,p5-bis(5'-adenosyl)pentaphosphate escherichia coli 1.0 1.0 1 PMID:11479323 -3.6.1.61 p1,p6-bis(5'-adenosyl)hexaphosphate thermus thermophilus 4.1 4.1 1 PMID:15024014 -3.6.1.62 adp homo sapiens 0.0959 0.0959 1 PMID:26121039 -3.6.1.62 itp homo sapiens 0.0127 0.0127 1 PMID:26121039 -3.6.1.62 xdp homo sapiens 0.0061 0.0061 1 PMID:26121039 -3.6.1.64 adp homo sapiens 0.096 0.096 1 PMID:26121039 -3.6.1.64 dgdp homo sapiens 0.008 0.008 1 PMID:20385596 -3.6.1.64 didp homo sapiens 0.016 0.016 1 PMID:20385596 -3.6.1.64 ditp homo sapiens 0.053 0.053 1 PMID:20385596 -3.6.1.64 gdp homo sapiens 0.009 0.009 1 PMID:20385596 -3.6.1.64 idp homo sapiens 0.016 0.016 1 PMID:20385596 -3.6.1.64 itp homo sapiens 0.051 0.032 2 PMID:20385596;PMID:26121039 -3.6.1.64 xdp homo sapiens 0.043 0.024499999999999997 2 PMID:20385596;PMID:26121039 -3.6.1.65 2-hydroxy-datp escherichia coli 0.17 0.17 1 PMID:15823026 -3.6.1.65 2-hydroxy-datp synechococcus phage s-pm2 1.93 1.93 1 PMID:30809954 -3.6.1.65 5-hydroxy-ctp escherichia coli 35.1 35.1 1 PMID:12509230 -3.6.1.65 5-methyl-dctp escherichia coli 51.7 43.35 2 PMID:11053429;PMID:15823026 -3.6.1.65 8-hydroxy-dgtp escherichia coli 0.89 0.89 1 PMID:15823026 -3.6.1.65 atp synechococcus phage s-pm2 1.48 1.48 1 PMID:30809954 -3.6.1.65 ctp escherichia coli 25.8 17.54 2 PMID:11053429;PMID:12509230 -3.6.1.65 ctp synechococcus phage s-pm2 1.62 1.62 1 PMID:30809954 -3.6.1.65 datp synechococcus phage s-pm2 1.05 1.05 1 PMID:30809954 -3.6.1.65 dctp escherichia coli 17.4 14.3 3 PMID:11053429;PMID:12509230;PMID:15823026 -3.6.1.65 dctp synechococcus phage s-pm2 5.75 5.75 1 PMID:30809954 -3.6.1.65 dgtp synechococcus phage s-pm2 6.67 6.67 1 PMID:30809954 -3.6.1.65 dttp synechococcus phage s-pm2 3.68 3.68 1 PMID:30809954 -3.6.1.65 dutp synechococcus phage s-pm2 4.94 4.94 1 PMID:30809954 -3.6.1.65 gtp synechococcus phage s-pm2 0.19 0.19 1 PMID:30809954 -3.6.1.65 utp synechococcus phage s-pm2 2.15 2.15 1 PMID:30809954 -3.6.1.66 ditp arabidopsis thaliana 1.5 1.5 1 PMID:36464781 -3.6.1.66 ditp methanocaldococcus jannaschii 152.4 152.4 1 PMID:11452035 -3.6.1.66 ditp thermotoga maritima 18.68 12.07 2 PMID:23385455 -3.6.1.66 ditp trypanosoma brucei brucei 280.0 280.0 1 PMID:35436992 -3.6.1.66 itp arabidopsis thaliana 1.9 1.9 1 PMID:36464781 -3.6.1.66 itp homo sapiens 4.7 4.7 1 PMID:37506994 -3.6.1.66 itp methanocaldococcus jannaschii 911.7 533.75 2 PMID:10404228;PMID:11452035 -3.6.1.66 itp thermotoga maritima 13.87 8.885 2 PMID:23385455 -3.6.1.66 itp trypanosoma brucei brucei 59.0 59.0 1 PMID:35436992 -3.6.1.66 ribavirin triphosphate trypanosoma brucei brucei 100.0 100.0 1 PMID:35436992 -3.6.1.66 xtp methanocaldococcus jannaschii 1009.0 592.7 2 PMID:10404228;PMID:11452035 -3.6.1.66 xtp thermotoga maritima 22.08 12.389999999999999 2 PMID:23385455 -3.6.1.66 xtp trypanosoma brucei brucei 37.0 37.0 1 PMID:35436992 -3.6.1.67 7,8-dihydroneopterin 3'-triphosphate arabidopsis thaliana 0.21 0.10529999999999999 2 PMID:15611104 -3.6.1.67 7,8-dihydroneopterin 3'-triphosphate escherichia coli 11.6 11.6 1 PMID:17698004 -3.6.1.67 7,8-dihydroneopterin 3'-triphosphate lactococcus lactis 0.21 0.21 1 PMID:15611104 -3.6.1.67 datp escherichia coli 4.59 4.59 1 PMID:17698004 -3.6.1.68 dimethylallyl diphosphate homo sapiens 0.94 0.94 1 PMID:38944687 -3.6.1.68 farnesyl diphosphate arabidopsis thaliana 1.91 1.91 1 PMID:32639596 -3.6.1.68 farnesyl diphosphate homo sapiens 0.52 0.52 1 PMID:38944687 -3.6.1.68 farnesyl diphosphate rosa chinensis 1.37 1.05 2 PMID:32639596 -3.6.1.68 farnesyl diphosphate rosa hybrid cultivar 1.21 1.21 1 PMID:32639596 -3.6.1.68 farnesyl diphosphate rosa lucieae 1.67 1.67 1 PMID:32639596 -3.6.1.68 geranyl diphosphate arabidopsis thaliana 0.26 0.26 1 PMID:32639596 -3.6.1.68 geranyl diphosphate homo sapiens 0.78 0.78 1 PMID:38944687 -3.6.1.68 geranyl diphosphate rosa chinensis 0.3 0.25 2 PMID:32639596 -3.6.1.68 geranyl diphosphate rosa hybrid cultivar 0.29 0.29 1 PMID:32639596 -3.6.1.68 geranyl diphosphate rosa lucieae 0.21 0.21 1 PMID:32639596 -3.6.1.68 geranylgeranyl diphosphate homo sapiens 0.15 0.15 1 PMID:38944687 -3.6.1.68 isopentenyl diphosphate homo sapiens 0.87 0.87 1 PMID:38944687 -3.6.1.68 mevalonate 5-diphosphate homo sapiens 0.55 0.55 1 PMID:38944687 -3.6.1.7 acetyl phosphate vibrio cholerae 1.55e-06 1.55e-06 1 PMID:24055378 -3.6.1.7 benzoyl phosphate bos taurus 117.0 117.0 1 PMID:8262761 -3.6.1.7 benzoyl phosphate pyrococcus horikoshii 10000.0 275.0 13 PMID:15779887;PMID:21423654 -3.6.1.7 benzoyl phosphate saccharolobus solfataricus 850.0 524.0 2 PMID:16287076 -3.6.1.7 benzoylphosphate drosophila melanogaster 735.0 735.0 1 PMID:12560098 -3.6.1.70 gppp-bodipy homo sapiens 0.0004 0.0004 1 PMID:15790557 -3.6.1.71 adenosine-5'-diphospho-5'-(ribonucleotide)-[dna] homo sapiens 0.31 0.31 1 PMID:24362567 -3.6.1.71 adenosine-5'-diphospho-5'-(ribonucleotide)-[dna] saccharomyces cerevisiae 0.23 0.23 1 PMID:24362567 -3.6.1.71 adenosine-5'-diphospho-5'-[dna] homo sapiens 0.51 0.38 3 PMID:24362567;PMID:29934293 -3.6.1.71 adenosine-5'-diphospho-5'-[dna] saccharomyces cerevisiae 0.32 0.32 1 PMID:24362567 -3.6.1.71 adenosine-5'-monophosphoramidate homo sapiens 0.0195 0.0195 1 PMID:16547001 -3.6.1.71 p1,p3-bis(5'-adenosyl)triphosphate homo sapiens 8e-05 8e-05 1 PMID:15790557 -3.6.1.71 p1,p4-bis(5'-adenosyl)tetraphosphate homo sapiens 0.0115 0.0062 2 PMID:15790557;PMID:16547001 -3.6.1.73 2'-deoxyinosine 5'-triphosphate escherichia coli 22.3 22.3 1 PMID:16216582 -3.6.1.73 guanosine 5'-triphosphate escherichia coli 616.5 616.5 1 PMID:16216582 -3.6.1.73 inosine 5'-triphosphate escherichia coli 573.3 573.3 1 PMID:16216582 -3.6.1.73 xanthosine 5'-triphosphate escherichia coli 2625.0 2625.0 1 PMID:16216582 -3.6.1.74 a 5'-triphospho-[mrna] semliki forest virus 0.092 0.092 1 PMID:10748213 -3.6.1.75 diacylglycerol diphosphate saccharomyces cerevisiae 96.67 68.785 2 PMID:8567632 -3.6.1.76 3-methylbut-3-en-1-yl diphosphate methanosarcina mazei 0.681 0.681 1 PMID:34864834 -3.6.1.76 farnesyl diphosphate methanosarcina mazei 0.298 0.298 1 PMID:34864834 -3.6.1.76 geranyl diphosphate methanosarcina mazei 0.395 0.395 1 PMID:34864834 -3.6.1.76 prenyl diphosphate methanosarcina mazei 0.139 0.139 1 PMID:34864834 -3.6.1.77 3'-dephospho-coa mus musculus 1.6 1.6 1 PMID:11415433 -3.6.1.77 acetyl-coa mus musculus 5.5 5.5 1 PMID:11415433 -3.6.1.77 coa mus musculus 4.73 4.73 1 PMID:29378847 -3.6.1.77 coa saccharomyces cerevisiae 4.6 4.6 1 PMID:10922370 -3.6.1.77 coa-s-s-coa mus musculus 2.1 2.1 1 PMID:11415433 -3.6.1.77 coenzyme a mus musculus 3.8 3.8 1 PMID:11415433 -3.6.1.77 oxidized coa disulfide saccharomyces cerevisiae 5.0 5.0 1 PMID:10922370 -3.6.1.77 succinyl-coa mus musculus 3.0 3.0 1 PMID:11415433 -3.6.1.9 2',3''-cgamp homo sapiens 5.36 5.36 1 PMID:30108800 -3.6.1.9 4-nitrophenyl-5'-adenosine monophosphate homo sapiens 2.51 2.51 1 PMID:30108800 -3.6.1.9 4-nitrophenyl-5'-thymidine monophosphate homo sapiens 22.3 22.3 1 PMID:30108800 -3.6.1.9 4-nitrophenyl-5'-tmp opuntia ficus-indica 1675.0 1675.0 1 * -3.6.1.9 adenosine 5'-phosphosulfate oryza sativa 329.0 76.0 3 PMID:24092883 -3.6.1.9 adp oryza sativa 449.0 266.0 2 PMID:24092883 -3.6.1.9 adp-glucose oryza sativa 214.0 172.0 2 PMID:24092883 -3.6.1.9 adp-ribose oryza sativa 370.0 370.0 1 PMID:24092883 -3.6.1.9 ap4a homo sapiens 5.65 5.65 1 PMID:30108800 -3.6.1.9 atp homo sapiens 5.51 5.51 1 PMID:30108800 -3.6.1.9 atp mus musculus 16.0 16.0 1 PMID:30108800 -3.6.1.9 atp oryza sativa 415.0 247.5 2 PMID:24092883 -3.6.1.9 atp thermotoga maritima 0.197 0.197 1 PMID:12657645 -3.6.1.9 bis(4-nitrophenyl) phosphate bothrops jararaca 44000.0 44000.0 1 PMID:19481561 -3.6.1.9 bis(4-nitrophenyl)phosphate oryza sativa 308.0 223.0 3 PMID:24092883 -3.6.1.9 camp homo sapiens 2.16 2.16 1 PMID:30108800 -3.6.1.9 cdp oryza sativa 89.0 89.0 1 PMID:24092883 -3.6.1.9 cdp-glucose oryza sativa 125.0 125.0 1 PMID:24092883 -3.6.1.9 ctp mus musculus 8.7 8.7 1 PMID:30108800 -3.6.1.9 ctp thermotoga maritima 0.11 0.11 1 PMID:12657645 -3.6.1.9 datp thermotoga maritima 1.12 1.12 1 PMID:12657645 -3.6.1.9 dctp thermotoga maritima 0.99 0.99 1 PMID:12657645 -3.6.1.9 dgtp thermotoga maritima 0.94 0.94 1 PMID:12657645 -3.6.1.9 diphosphate oryza sativa 79.0 59.5 2 PMID:24092883 -3.6.1.9 ditp homo sapiens 360.0 360.0 1 PMID:11278832 -3.6.1.9 dttp escherichia coli 43.0 43.0 1 PMID:25658941 -3.6.1.9 dttp thermotoga maritima 0.65 0.65 1 PMID:12657645 -3.6.1.9 gdp oryza sativa 8.0 8.0 1 PMID:24092883 -3.6.1.9 gdp-mannose oryza sativa 151.0 151.0 1 PMID:24092883 -3.6.1.9 gtp mus musculus 820.0 820.0 1 PMID:30108800 -3.6.1.9 gtp thermotoga maritima 0.69 0.69 1 PMID:12657645 -3.6.1.9 idp oryza sativa 88.0 88.0 1 PMID:24092883 -3.6.1.9 itp homo sapiens 580.0 580.0 1 PMID:11278832 -3.6.1.9 nad+ opuntia ficus-indica 197.0 197.0 1 * -3.6.1.9 nadh opuntia ficus-indica 828.0 828.0 1 * -3.6.1.9 nadp+ opuntia ficus-indica 110.0 110.0 1 * -3.6.1.9 nadph opuntia ficus-indica 745.0 745.0 1 * -3.6.1.9 p-nitrophenyl 5'-thymidine monophosphate bothrops jararaca 960000.0 960000.0 1 PMID:19481561 -3.6.1.9 tdp oryza sativa 87.0 87.0 2 PMID:24092883 -3.6.1.9 tdp-glucose oryza sativa 124.0 102.5 2 PMID:24092883 -3.6.1.9 udp oryza sativa 104.0 102.5 2 PMID:24092883 -3.6.1.9 udp-glucose oryza sativa 282.0 198.5 2 PMID:24092883 -3.6.1.9 utp escherichia coli 95.0 95.0 1 PMID:25658941 -3.6.1.9 utp homo sapiens 1.96 1.96 1 PMID:30108800 -3.6.1.9 utp mus musculus 200.0 200.0 1 PMID:30108800 -3.6.1.9 utp thermotoga maritima 0.18 0.18 1 PMID:12657645 -3.6.1.9 xanthosine 5'-triphosphate homo sapiens 640.0 640.0 1 PMID:11278832 -3.6.4.6 atp saccharomyces cerevisiae 0.85 0.85 1 PMID:21925211 -3.6.5.1 gtp bos taurus 21.0 21.0 1 PMID:8395213 -3.6.5.1 gtp mus musculus 0.019 0.0104 2 PMID:16207703 -3.6.5.1 gtp oryza sativa 2.118 0.6 9 PMID:12689519 -3.6.5.1 gtp saccharolobus solfataricus 9.9 3.1 12 PMID:10336648;PMID:7673137 -3.6.5.2 gtp homo sapiens 0.0005 0.0005 1 PMID:1898771 -3.6.5.3 gtp escherichia coli 202.0 27.0 9 PMID:25712150;PMID:26229983;PMID:26264741 -3.6.5.3 gtp saccharolobus solfataricus 8.8 0.078 30 PMID:10336648;PMID:11781103;PMID:12586405;PMID:19787775;PMID:20400571;PMID:21478358;PMID:21599854;PMID:21924318;PMID:7673137;PMID:9030774;PMID:9116052;PMID:9258439 -3.6.5.4 atp mycobacterium tuberculosis 0.007 0.007 1 PMID:33412199 -3.6.5.4 gtp escherichia coli 0.223 0.13 2 PMID:17164479 -3.6.5.4 gtp lathyrus oleraceus 8e-05 3.2e-05 9 PMID:30611779 -3.6.5.4 gtp mycobacterium tuberculosis 0.0122 0.00875 14 PMID:33412199 -3.6.5.4 gtp sulfolobus acidocaldarius 0.0069 0.005 7 PMID:34116357 -3.6.5.5 gtp bos taurus 3.1 3.1 1 PMID:11242086 -3.6.5.5 gtp homo sapiens 1.75 0.0865 4 PMID:15262989 -3.6.5.5 gtp rattus norvegicus 0.024 0.024 1 PMID:16141317 -3.6.5.6 gtp bos taurus 0.0083 0.0002165 12 PMID:16675842;PMID:17711308;PMID:2825770;PMID:8193140 -3.6.5.6 gtp prosthecobacter sp. 0.022 0.01435 2 PMID:15851515 -3.6.5.6 gtp saccharomyces cerevisiae 1500.0 1500.0 1 PMID:11747449 -3.7.1.1 (2r,3s)-2,3-dimethylmalate botrytis cinerea 0.0293 0.0293 1 PMID:17654546 -3.7.1.1 (2r,3s)-2-ethyl-3-methylmalate dianthus caryophyllus 8.4 8.4 1 PMID:17654546 -3.7.1.1 oxaloacetate aspergillus niger 0.505 0.4925 2 PMID:19133276 -3.7.1.1 oxaloacetate botrytis cinerea 50.0 12.15 10 PMID:17244616;PMID:17654546 -3.7.1.1 oxaloacetate cryphonectria parasitica 35.2 3.6 3 PMID:20558740 -3.7.1.1 oxaloacetate dianthus caryophyllus 2.72 2.72 1 PMID:17654546 -3.7.1.11 cyclohexane-1,2-dione azoarcus sp. 1.6 1.6 1 PMID:22309255 -3.7.1.13 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoic acid pseudomonas sp. 1300.0 1300.0 1 PMID:12651123 -3.7.1.13 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate arthrobacter sp. yc-rl1 11.61 11.61 1 PMID:31240368 -3.7.1.13 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate janthinobacterium sp. j3 1.99 1.99 1 PMID:12659866 -3.7.1.13 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate metapseudomonas resinovorans 2.14 2.12 2 PMID:12619671;PMID:12659866 -3.7.1.14 (2e,4z)-2-hydroxy-6-oxonona-2,4-dienedioate escherichia coli 8.0 8.0 2 PMID:15663941;PMID:17029402 -3.7.1.14 2-hydroxy-6-keto-6-phenylhexa-2,4-dienoic acid escherichia coli 0.036 0.036 1 PMID:17029401 -3.7.1.17 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid mycobacterium tuberculosis 0.25 0.158 2 PMID:19014350;PMID:19875455 -3.7.1.17 4,5-9,10-diseco-3-hydroxy-5,9,17-tri-oxoandrosta-1(10),2-diene-4-oic acid mycobacterium tuberculosis 0.55 0.55 1 PMID:19875455 -3.7.1.17 8-(2-chlorophenyl)-2-hydroxy-5-methyl-6-oxoocta-2,4-dienoic acid mycobacterium tuberculosis 0.33 0.33 1 PMID:19875455 -3.7.1.18 6-oxocamphor rhodococcus sp. (in: high g+c gram-positive bacteria) 642.9 404.95 2 PMID:11278926;PMID:15138275 -3.7.1.19 2,6-dihydroxypseudooxynicotine paenarthrobacter nicotinovorans 792.0 792.0 1 PMID:16321959 -3.7.1.2 4-fumarylacetoacetate homo sapiens 0.1 0.1 1 PMID:31300554 -3.7.1.23 3-maleylpyruvate sphingobium sp. syk-6 0.063 0.063 1 PMID:31079929 -3.7.1.24 2,4-diacetylphloroglucinol pseudomonas fluorescens 33.0 18.85 2 PMID:16391073;PMID:20018877 -3.7.1.24 2,4-diacetylphloroglucinol pseudomonas sp. 5.8 5.8 1 PMID:22790955 -3.7.1.26 acetylpyruvate sphingomonas sp. ska58 0.237 0.237 1 PMID:36563174 -3.7.1.26 trimethylacetopyruvate sphingomonas sp. ska58 0.58 0.58 1 PMID:36563174 -3.7.1.3 (2s)-2-amino-4-oxo-4-phenylbutanoic acid pseudomonas fluorescens 0.7 0.7 1 PMID:15023073 -3.7.1.3 2-amino-4-(2-chlorophenyl)-4-oxobutanoic acid pseudomonas fluorescens 0.08 0.08 1 PMID:20690660 -3.7.1.3 2-amino-4-(2-methoxyphenyl)-4-oxobutanoic acid pseudomonas fluorescens 0.05 0.05 1 PMID:20690660 -3.7.1.3 2-amino-4-(4-methoxyphenyl)-4-oxobutanoic acid pseudomonas fluorescens 0.38 0.38 1 PMID:20690660 -3.7.1.3 2-fluorobenzoyl-dl-alanine pseudomonas fluorescens 0.06 0.06 1 PMID:20690660 -3.7.1.3 3,5-dibromo-l-kynurenine homo sapiens 1.2 1.2 1 PMID:23791867 -3.7.1.3 3,5-dibromo-l-kynurenine pseudomonas fluorescens 0.23 0.23 1 PMID:23791867 -3.7.1.3 3-bromo-l-kynurenine homo sapiens 1.9 1.9 1 PMID:23791867 -3.7.1.3 3-bromo-l-kynurenine pseudomonas fluorescens 11.0 11.0 1 PMID:23791867 -3.7.1.3 3-chloro-dl-kynurenine homo sapiens 0.67 0.67 1 PMID:23791867 -3.7.1.3 3-chloro-dl-kynurenine pseudomonas fluorescens 0.71 0.71 1 PMID:23791867 -3.7.1.3 3-fluoro-dl-kynurenine homo sapiens 0.23 0.23 1 PMID:23791867 -3.7.1.3 3-fluoro-dl-kynurenine pseudomonas fluorescens 6.9 6.9 1 PMID:23791867 -3.7.1.3 3-hydroxy-dl-kynurenine homo sapiens 3.5 3.5 1 PMID:17300176 -3.7.1.3 3-hydroxy-l-kynurenine homo sapiens 3.5 3.5 2 PMID:19143568;PMID:23791867 -3.7.1.3 3-hydroxy-l-kynurenine pseudomonas fluorescens 1.0 1.0 1 PMID:23791867 -3.7.1.3 3-methyl-dl-kynurenine homo sapiens 0.33 0.33 1 PMID:23791867 -3.7.1.3 3-methyl-dl-kynurenine pseudomonas fluorescens 1.5 1.5 1 PMID:23791867 -3.7.1.3 5-bromo-3-chloro-dl-kynurenine homo sapiens 1.3 1.3 1 PMID:23791867 -3.7.1.3 5-bromo-3-chloro-dl-kynurenine pseudomonas fluorescens 6.3 6.3 1 PMID:23791867 -3.7.1.3 5-bromo-l-kynurenine homo sapiens 0.63 0.63 1 PMID:23791867 -3.7.1.3 5-bromo-l-kynurenine pseudomonas fluorescens 11.9 11.9 1 PMID:23791867 -3.7.1.3 5-chloro-l-kynurenine homo sapiens 0.47 0.47 1 PMID:23791867 -3.7.1.3 5-chloro-l-kynurenine pseudomonas fluorescens 8.7 8.7 1 PMID:23791867 -3.7.1.3 beta-(4-chlorobenzoyl)-dl-alanine pseudomonas fluorescens 1.83 1.83 1 PMID:20690660 -3.7.1.3 beta-(4-methylbenzoyl)-dl-alanine pseudomonas fluorescens 0.91 0.91 1 PMID:20690660 -3.7.1.3 beta-(4-trifluoromethylbenzoyl)-dl-alanine pseudomonas fluorescens 0.001 0.001 1 PMID:20690660 -3.7.1.3 beta-benzoyl-l-alanine pseudomonas fluorescens 0.7 0.7 2 PMID:15023073;PMID:31100408 -3.7.1.3 l-kynurenine homo sapiens 0.23 0.23 2 PMID:19143568;PMID:23791867 -3.7.1.3 l-kynurenine pseudomonas fluorescens 16.0 16.0 4 PMID:15023073;PMID:23791867;PMID:24304904;PMID:31100408 -3.7.1.3 o-benzoyl-l-serine pseudomonas fluorescens 2.5 2.5 2 PMID:24304904;PMID:31100408 -3.7.1.4 lactose rattus norvegicus 47.0 47.0 1 PMID:12023280 -3.7.1.4 monoacetylphloroglucinol mycobacteroides abscessus 49.6 49.6 1 PMID:30784195 -3.7.1.4 phloretin eubacterium ramulus 10.0 10.0 2 PMID:15466559 -3.7.1.4 phloretin mycobacteroides abscessus 0.85 0.85 1 PMID:30784195 -3.7.1.4 pyridoxine-5'-beta-d-glucoside rattus norvegicus 1.0 1.0 1 PMID:12023280 -3.7.1.7 bicyclo[2.2.2]octane-2,6-dione nostoc sp. pcc 7120 = fachb-418 0.16 0.16 1 PMID:17198383 -3.7.1.8 (2e,4e)-2-hydroxy-6-(4-chlorophenyl)-6-oxohexa-2,4-dienoic acid burkholderia cepacia 3.13 3.13 1 PMID:10821847 -3.7.1.8 (2e,4e)-2-hydroxy-6-(4-chlorophenyl)-6-oxohexa-2,4-dienoic acid rhodococcus globerulus 33.7 33.7 1 PMID:11160080 -3.7.1.8 (2e,4e)-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid burkholderia cepacia 4.18 4.18 1 PMID:10821847 -3.7.1.8 (2e,4e)-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid rhodococcus globerulus 7.6 7.6 1 PMID:11160080 -3.7.1.8 (2e,4e)-6-(2-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid burkholderia cepacia 2.1 2.1 1 PMID:10821847 -3.7.1.8 (2e,4e)-6-(2-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid rhodococcus globerulus 1.74 1.74 1 PMID:11160080 -3.7.1.8 (2e,4e)-6-(3,4-dichlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid rhodococcus globerulus 29.0 29.0 1 PMID:11160080 -3.7.1.8 (2e,4e)-6-(3,5-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid rhodococcus globerulus 11.2 11.2 1 PMID:11160080 -3.7.1.8 (2e,4e)-6-(3-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid burkholderia cepacia 3.9 3.9 1 PMID:10821847 -3.7.1.8 (2e,4e)-6-(3-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid rhodococcus globerulus 15.3 15.3 1 PMID:11160080 -3.7.1.8 (2e,4z)-2,4-dihydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid burkholderia cepacia 0.0055 0.0055 1 PMID:10821847 -3.7.1.8 (2e,4z)-4-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid burkholderia cepacia 0.00059 0.00059 1 PMID:10821847 -3.7.1.8 (2e,4z)-5-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid burkholderia cepacia 1.53 1.53 1 PMID:10821847 -3.7.1.8 (2e,4z)-5-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid rhodococcus globerulus 1.03 1.03 1 PMID:11160080 -3.7.1.8 (2z,4e)-3-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid burkholderia cepacia 0.0089 0.0089 1 PMID:10821847 -3.7.1.8 (2z,4e)-3-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid rhodococcus globerulus 0.0172 0.0172 1 PMID:11160080 -3.7.1.8 2,6-dioxo-6-phenylhexa-3-enoate dyella ginsengisoli 9.6 9.6 1 PMID:23494625 -3.7.1.8 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoic acid pseudomonas sp. 1300.0 1300.0 1 PMID:12651123 -3.7.1.8 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate arthrobacter sp. yc-rl1 11.61 11.61 1 PMID:31240368 -3.7.1.8 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate bacillus sp. (in: firmicutes) 1.11 1.11 1 PMID:16339959 -3.7.1.8 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid mycobacterium tuberculosis 0.066 0.066 1 PMID:19875455 -3.7.1.8 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid paraburkholderia xenovorans 26.0 6.5 5 PMID:16964968;PMID:22747426 -3.7.1.8 4,11-dicarboxy-8-hydroxy-9-methoxy-2-hydroxy-6-oxo-6-phenyl-hexa-2,4-dienoate sphingobium sp. syk-6 9.7 9.7 1 * -3.7.1.8 4-nitrophenyl benzoate paraburkholderia xenovorans 6.3 6.3 1 PMID:22747426 -3.7.1.8 8-(2-chlorophenyl)-2-hydroxy-5-methyl-6-oxoocta-2,4-dienoic acid mycobacterium tuberculosis 0.33 0.33 1 PMID:19875455 -3.7.1.8 ethyl-2-acetoxy-6-keto-6-phenylhexa-2,4-dienoate paraburkholderia xenovorans 6.5 6.5 1 PMID:17029401 -3.7.1.8 meta-ring fission intermediate escherichia coli 12.0 0.5 8 PMID:17029402 -3.7.1.8 meta-ring fission intermediate paraburkholderia xenovorans 6.5 0.016 3 PMID:17029402 -3.7.1.9 2-hydroxy-5-methylmuconate-6-semialdehyde pseudomonas sp. 1.15 1.15 1 PMID:23009925 -3.7.1.9 2-hydroxy-5-methylmuconic semialdehyde flavobacterium sp. 16.0 16.0 1 PMID:17078928 -3.7.1.9 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate pseudomonas fluorescens 0.037 0.0335 2 PMID:16233251;PMID:16844437 -3.7.1.9 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate pseudomonas fluorescens 23.1 22.05 2 PMID:16233251;PMID:16844437 -3.7.1.9 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate pseudomonas putida 0.41 0.41 1 PMID:16844437 -3.7.1.9 2-hydroxy-6-oxohepta-2,4-dienoate flavobacterium sp. 57.0 57.0 1 PMID:17078928 -3.7.1.9 2-hydroxy-6-oxohepta-2,4-dienoate pseudomonas fluorescens 19.5 18.75 2 PMID:16233251;PMID:16844437 -3.7.1.9 2-hydroxy-6-oxohepta-2,4-dienoate pseudomonas putida 35.0 35.0 1 PMID:16844437 -3.7.1.9 2-hydroxy-6-oxohepta-2,4-dienoate pseudomonas sp. 36.53 36.53 1 PMID:23009925 -3.7.1.9 2-hydroxy-6-oxoocta-2,4-dienoate pseudomonas fluorescens 42.4 41.7 2 PMID:16233251;PMID:16844437 -3.7.1.9 2-hydroxy-6-oxoocta-2,4-dienoate pseudomonas putida 14.0 14.0 1 PMID:16844437 -3.7.1.9 2-hydroxymuconate-6-semialdehyde pseudomonas sp. 18.2 18.2 1 PMID:23009925 -3.7.1.9 2-hydroxymuconic semialdehyde flavobacterium sp. 42.0 42.0 1 PMID:17078928 -3.8.1.2 2-chloroacetate polaromonas sp. js666 5.33 5.33 1 PMID:34643018 -3.8.1.2 2-chloroacetate pseudomonas aeruginosa 0.067 0.067 1 PMID:34643018 -3.8.1.2 2-chloroacetate ralstonia solanacearum 8.33 8.33 1 PMID:34643018 -3.8.1.2 2-chloroacetate rhodococcus jostii rha1 0.67 0.67 1 PMID:34643018 -3.8.1.2 2-chloroacetate sulfurisphaera tokodaii 0.26 0.26 1 PMID:34643018 -3.8.1.2 2-fluoroacetate polaromonas sp. js666 0.22 0.22 1 PMID:34643018 -3.8.1.2 2-fluoroacetate rhodococcus jostii rha1 0.28 0.28 1 PMID:34643018 -3.8.1.2 2-fluoroacetate sulfurisphaera tokodaii 0.12 0.12 1 PMID:34643018 -3.8.1.2 monochloroacetate ancylobacter aquaticus 0.08 0.08 1 PMID:26645146 -3.8.1.3 2-fluoropropionic acid rhodopseudomonas palustris 5.5 5.5 1 PMID:31319293 -3.8.1.3 difluoroacetate delftia acidovorans 0.000206 0.00019999999999999998 2 PMID:38973860 -3.8.1.3 fluoroacetate delftia acidovorans 0.00133 0.000772 2 PMID:38973860 -3.8.1.5 1,2,3-tribromopropane rhodococcus rhodochrous 3.6 3.6 1 PMID:12834356 -3.8.1.5 1,2,3-trichloropropane bradyrhizobium japonicum 0.24 0.24 1 PMID:16085827 -3.8.1.5 1,2,3-trichloropropane rhodococcus rhodochrous 0.08 0.08 1 PMID:12834356 -3.8.1.5 1,2,3-trichloropropane sphingobium indicum 0.005 0.005 1 PMID:17259360 -3.8.1.5 1,2-dibromoethane alloalcanivorax dieselolei 17.95 17.95 1 PMID:24586552 -3.8.1.5 1,2-dibromoethane lyngbya majuscula 1.8 1.8 1 PMID:29101190 -3.8.1.5 1,2-dibromoethane plesiocystis pacifica 0.38 0.38 1 PMID:21603934 -3.8.1.5 1,2-dibromoethane rhodococcus rhodochrous 14.3 14.3 1 PMID:12834356 -3.8.1.5 1,2-dibromoethane sphingomonas paucimobilis 26.4 26.4 1 PMID:14525993 -3.8.1.5 1,2-dibromopropane bradyrhizobium japonicum 0.96 0.96 1 PMID:16085827 -3.8.1.5 1,2-dibromopropane plesiocystis pacifica 1.97 1.97 1 PMID:21603934 -3.8.1.5 1,2-dibromopropane rhodococcus rhodochrous 2.3 2.3 1 PMID:12834356 -3.8.1.5 1,2-dichloroethane ancylobacter aquaticus 2.37 2.37 1 PMID:24642226 -3.8.1.5 1,2-dichloroethane sphingomonas paucimobilis 1.05 1.05 1 PMID:11939779 -3.8.1.5 1,2-dichloropropane sphingomonas paucimobilis 0.91 0.91 1 PMID:11939779 -3.8.1.5 1,3-dibromopropane agrobacterium tumefaciens 1.5 1.4849999999999999 2 PMID:21193677;PMID:23490078 -3.8.1.5 1,3-dibromopropane alloalcanivorax dieselolei 13.39 13.39 1 PMID:24586552 -3.8.1.5 1,3-dibromopropane bradyrhizobium japonicum 3.6 3.6 1 PMID:16085827 -3.8.1.5 1,3-dibromopropane caulobacter vibrioides 29.0 29.0 2 PMID:26833751 -3.8.1.5 1,3-dibromopropane mycobacterium tuberculosis variant bovis 9.2 9.2 1 PMID:16269704 -3.8.1.5 1,3-dibromopropane psychrobacter cryohalolentis 2.72 2.72 1 PMID:22582053 -3.8.1.5 1,3-dibromopropane rhodococcus rhodochrous 2.7 2.7 1 PMID:12834356 -3.8.1.5 1,3-dibromopropane sphingomonas paucimobilis 6.6 6.6 1 PMID:15736949 -3.8.1.5 1,3-dibromopropane strongylocentrotus purpuratus 1.57 1.57 1 PMID:23939220 -3.8.1.5 1,3-dibromopropane uncultured marine bacterium 2.4 2.4 1 PMID:22124946 -3.8.1.5 1,3-dichloropropane agrobacterium tumefaciens 0.01 0.009000000000000001 2 PMID:21193677;PMID:23490078 -3.8.1.5 1,3-dichloropropane rhodococcus rhodochrous 1.3 1.3 1 PMID:12834356 -3.8.1.5 1,3-diiodopropane agrobacterium tumefaciens 1.2 1.2 2 PMID:21193677;PMID:23490078 -3.8.1.5 1,5-dichloropentane caulobacter vibrioides 5.0 5.0 2 PMID:26833751 -3.8.1.5 1,5-dichloropentane sphingomonas paucimobilis 2.45 2.45 1 PMID:15736949 -3.8.1.5 1-bromo-2-methylpropane sphingomonas paucimobilis 1.6 1.6 1 PMID:15736949 -3.8.1.5 1-bromobutane agrobacterium tumefaciens 1.5 1.5 1 PMID:23490078 -3.8.1.5 1-bromobutane caulobacter vibrioides 13.0 13.0 2 PMID:26833751 -3.8.1.5 1-bromobutane plesiocystis pacifica 8.08 8.08 1 PMID:21603934 -3.8.1.5 1-bromobutane psychrobacter cryohalolentis 1.1 1.1 1 PMID:22582053 -3.8.1.5 1-bromobutane sphingomonas paucimobilis 3.41 3.41 1 PMID:15736949 -3.8.1.5 1-bromodecane yarrowia lipolytica 0.1 0.1 1 PMID:28928379 -3.8.1.5 1-bromododecane yarrowia lipolytica 0.16 0.16 1 PMID:28928379 -3.8.1.5 1-bromoheptane plesiocystis pacifica 1.39 1.39 1 PMID:21603934 -3.8.1.5 1-bromohexane agrobacterium tumefaciens 1.7 1.7 2 PMID:21193677;PMID:23490078 -3.8.1.5 1-bromohexane caulobacter vibrioides 23.6 23.6 2 PMID:26833751 -3.8.1.5 1-bromohexane plesiocystis pacifica 2.69 2.69 1 PMID:21603934 -3.8.1.5 1-bromohexane sphingomonas paucimobilis 1.05 1.05 1 PMID:15736949 -3.8.1.5 1-bromopentane plesiocystis pacifica 9.94 9.94 1 PMID:21603934 -3.8.1.5 1-bromopropane plesiocystis pacifica 5.85 5.85 1 PMID:21603934 -3.8.1.5 1-bromopropane rhodococcus rhodochrous 2.7 2.7 1 PMID:12834356 -3.8.1.5 1-bromopropane yarrowia lipolytica 1.57 1.57 1 PMID:28928379 -3.8.1.5 1-chlorobutane alloalcanivorax dieselolei 1.17 1.17 1 PMID:24586552 -3.8.1.5 1-chlorobutane bradyrhizobium japonicum 1.4 1.4 1 PMID:16085827 -3.8.1.5 1-chlorobutane lyngbya majuscula 0.17 0.17 1 PMID:29101190 -3.8.1.5 1-chlorobutane mycobacterium tuberculosis variant bovis 0.08 0.08 1 PMID:16269704 -3.8.1.5 1-chlorobutane sphingomonas paucimobilis 1.055 1.055 1 PMID:14525993 -3.8.1.5 1-chloroheptane sphingomonas paucimobilis 6.0 4.6725 2 PMID:15736949 -3.8.1.5 1-chlorohexane agrobacterium tumefaciens 0.07 0.05450000000000001 2 PMID:21193677;PMID:23490078 -3.8.1.5 1-chlorohexane bradyrhizobium japonicum 1.4 1.4 1 PMID:16085827 -3.8.1.5 1-chlorohexane caulobacter vibrioides 3.1 3.1 2 PMID:26833751 -3.8.1.5 1-chlorohexane sphingomonas paucimobilis 6.08 3.5564999999999998 2 PMID:15736949 -3.8.1.5 1-chlorooctane sphingomonas paucimobilis 2.75 2.75 1 PMID:15736949 -3.8.1.5 1-chloropropane rhodococcus rhodochrous 0.48 0.48 1 PMID:12834356 -3.8.1.5 1-iodobutane lyngbya majuscula 0.21 0.21 1 PMID:29101190 -3.8.1.5 1-iodohexane agrobacterium tumefaciens 0.26 0.26 1 PMID:21193677 -3.8.1.5 1-iodohexane sphingomonas paucimobilis 2.33 2.33 1 PMID:15736949 -3.8.1.5 1-iodopropane lyngbya majuscula 0.43 0.43 1 PMID:29101190 -3.8.1.5 2,3-dichloroprop-1-ene alloalcanivorax dieselolei 20.06 20.06 1 PMID:24586552 -3.8.1.5 2-bromoethanol rhodococcus rhodochrous 3.0 3.0 1 PMID:12834356 -3.8.1.5 3-bromo-1-propanol rhodococcus rhodochrous 3.0 3.0 1 PMID:12834356 -3.8.1.5 3-chloro-2-(chloromethyl)-1-propene sphingomonas paucimobilis 8.17 8.17 1 PMID:15736949 -3.8.1.5 3-chloro-2-methylprop-1-ene alloalcanivorax dieselolei 34.26 34.26 1 PMID:24586552 -3.8.1.5 3-chloro-2-methylpropene bradyrhizobium japonicum 3.5 3.5 1 PMID:16085827 -3.8.1.5 4-bromobutyronitrile alloalcanivorax dieselolei 30.8 30.8 1 PMID:24586552 -3.8.1.5 4-bromobutyronitrile lyngbya majuscula 1.2 1.2 1 PMID:29101190 -3.8.1.5 4-bromobutyronitrile mycolicibacterium rhodesiae 3.1 3.1 1 PMID:25899475 -3.8.1.5 4-bromomethyl-6,7-dimethoxycoumarin rhodococcus rhodochrous 107000.0 84000.0 3 PMID:37836637 -3.8.1.5 bis(2-chloroethyl) ether rhodococcus rhodochrous 3.01 1.0 7 PMID:28587829;PMID:34118331;PMID:34311877 -3.8.1.5 bromocyclohexane bradyrhizobium japonicum 0.59 0.59 1 PMID:16085827 -3.8.1.5 bromocyclohexane sphingomonas paucimobilis 1.36 1.36 1 PMID:15736949 -3.8.1.5 chlorocyclohexane bradyrhizobium japonicum 0.25 0.25 1 PMID:16085827 -3.8.1.7 2,4,5,6-tetrachloroisophthalonitrile pseudomonas sp. 207.0 207.0 1 PMID:20363940 -3.8.1.7 2,4-dichlorobenzoyl-coa pseudomonas sp. 0.511 0.511 1 PMID:7765837;PMID:8218302 -3.8.1.7 3,4-dichlorobenzoyl-coa pseudomonas sp. 0.052 0.052 1 PMID:7765837;PMID:8218302 -3.8.1.7 4-bromobenzoyl-coa arthrobacter sp. 2.4 2.4 1 PMID:7918379 -3.8.1.7 4-bromobenzoyl-coa pseudomonas sp. 1.4 1.4 1 PMID:7765837;PMID:8218302 -3.8.1.7 4-bromophenacyl-coa pseudomonas sp. 0.03 0.03 1 PMID:11747444 -3.8.1.7 4-chloro-2-nitrobenzoyl-coa pseudomonas sp. 0.063 0.063 1 PMID:7765837;PMID:8218302 -3.8.1.7 4-chlorobenzoyl-3'-dephospho-coa pseudomonas sp. 0.45 0.45 1 PMID:11747444 -3.8.1.7 4-chlorobenzoyl-coa arthrobacter sp. 1.3 1.15 2 PMID:15068371;PMID:7918379 -3.8.1.7 4-chlorobenzoyl-coa pseudomonas sp. 5.0 0.6499999999999999 8 PMID:11695894;PMID:11747444;PMID:12899635;PMID:1610806;PMID:16388585;PMID:7579994;PMID:8218302 -3.8.1.7 4-chlorobenzoyl-dithio-coa pseudomonas sp. 0.003 0.003 1 PMID:11747444 -3.8.1.7 4-chlorobenzoyl-epsilon-coa pseudomonas sp. 0.007 0.007 1 PMID:11747444 -3.8.1.7 4-chlorobenzoyl-pantetheine pseudomonas sp. 0.056 0.0285 2 PMID:11747444 -3.8.1.7 4-chlorobenzoyl-pantetheine phosphate pseudomonas sp. 0.051 0.051 1 PMID:11747444 -3.8.1.7 4-fluorobenzoyl-coa arthrobacter sp. 0.003 0.003 1 PMID:7918379 -3.8.1.7 4-iodobenzoyl-coa arthrobacter sp. 2.0 2.0 1 PMID:7918379 -3.8.1.7 4-iodobenzoyl-coa pseudomonas sp. 1.1 1.1 1 PMID:7765837;PMID:8218302 -3.8.1.8 2,4-diisopropylamino-6-hydroxy-1,3,5-triazine pseudomonas sp. 0.8 0.8 1 PMID:17660279 -3.8.1.8 2-(n-ethylamino)-4-hydroxy-6-(n-isopropylamino)-1,3,5-triazine pseudomonas sp. 3.2 3.2 1 PMID:17660279 -3.8.1.8 2-chloro-4-(n-ethylamino)-6-hydroxy-1,3,5-triazine pseudomonas sp. 1.6 1.6 1 PMID:17660279 -3.8.1.8 2-chloro-4-hydroxy-6-(n-isopropylamino)-1,3,5-triazine pseudomonas sp. 1.9 1.9 1 PMID:17660279 -3.8.1.8 6-hydroxy-4-(n-isopropylamino)-2-(n-methylamino)-1,3,5-triazine pseudomonas sp. 1.4 1.4 1 PMID:17660279 -3.8.1.8 ametryn paenarthrobacter aurescens 6.04 6.04 1 PMID:20659898 -3.8.1.8 atrazine escherichia coli 27.9 7.1 12 PMID:19201959 -3.8.1.8 atrazine haematococcus lacustris 5.86 4.06 11 PMID:27010688 -3.8.1.8 atrazine paenarthrobacter aurescens 1.49 1.49 1 PMID:20659898 -3.8.1.8 atrazine pseudomonas sp. 11.0 6.3 2 PMID:24237144;PMID:8759853 -3.8.1.8 atrazine thermotoga maritima 2.2 2.2 1 PMID:19201959 -3.8.1.8 hydroxyatrazine pseudomonas sp. 3.0 3.0 1 PMID:17660279 -3.8.1.9 d-2-chloropropionate pseudomonas putida 16.35 16.35 1 PMID:29362453 -3.8.2.2 coumaphos brevundimonas diminuta 610.0 610.0 1 PMID:20890601 -3.8.2.2 diazinon brevundimonas diminuta 176.0 176.0 1 PMID:20890601 -3.8.2.2 diisopropyl fluorophosphate alteromonas sp. 583.0 406.5 2 PMID:2001997;PMID:20890601 -3.8.2.2 diisopropyl fluorophosphate brevundimonas diminuta 465.0 465.0 1 PMID:20890601 -3.8.2.2 diisopropyl fluorophosphate homo sapiens 20.35 15.02 2 PMID:27838376 -3.8.2.2 diisopropyl fluorophosphate loligo vulgaris 2111.0 2091.0 5 PMID:11295437;PMID:17002369;PMID:19894712 -3.8.2.2 diisopropyl fluorophosphate pseudoalteromonas undina 917.0 917.0 1 PMID:16349054 -3.8.2.2 diisopropyl fluorophosphate sphingobium fuliginis 0.0477 0.01865 22 PMID:28085964 -3.8.2.2 fensulfothion brevundimonas diminuta 67.0 67.0 1 PMID:20890601 -3.8.2.2 methyl parathion brevundimonas diminuta 189.0 189.0 1 PMID:20890601 -3.8.2.2 o-cyclohexyl methylphosphonofluoridate alteromonas sp. 652.0 652.0 1 PMID:20890601 -3.8.2.2 o-ethyl s-(2-diisopropylamino)ethyl methylphosphonothioate brevundimonas diminuta 0.3 0.3 1 PMID:20890601 -3.8.2.2 o-isopropylmethylphosphonofluoridate alteromonas sp. 442.0 442.0 1 PMID:20890601 -3.8.2.2 o-isopropylmethylphosphonofluoridate brevundimonas diminuta 56.0 56.0 1 PMID:20890601 -3.8.2.2 o-pinacolyl methylphosphonofluoridate alteromonas sp. 151.0 151.0 1 PMID:20890601 -3.8.2.2 o-pinacolyl methylphosphonofluoridate brevundimonas diminuta 5.0 5.0 1 PMID:20890601 -3.8.2.2 paraoxon alteromonas sp. 6.11 6.11 1 PMID:20890601 -3.8.2.2 paraoxon brevundimonas diminuta 3170.0 3170.0 1 PMID:20890601 -3.8.2.2 parathion brevundimonas diminuta 630.0 630.0 1 PMID:20890601 -3.9.1.2 4-nitrophenyl phosphate geobacillus stearothermophilus 1.12 1.12 1 PMID:23838530 -3.9.1.2 phospho-l-arginine drosophila melanogaster 0.257 0.257 1 PMID:33372666 -3.9.1.3 4-nitrophenylphosphate homo sapiens 0.35 0.35 1 PMID:29630837 -3.9.1.3 6,8-difluoromethylumbelliferyl phosphate homo sapiens 0.39 0.39 1 PMID:29630837 -4.1.1.1 2-keto-4-methylhexanoic acid zymomonas mobilis 0.4 0.4 1 PMID:15930043 -4.1.1.1 2-ketobutanoic acid zymomonas mobilis 320.0 320.0 1 PMID:15930043 -4.1.1.1 2-ketobutyrate zymomonas mobilis 61.4 35.2 2 PMID:10924138 -4.1.1.1 2-ketohexanoic acid zymomonas mobilis 4.0 4.0 1 PMID:15930043 -4.1.1.1 2-ketopentanoic acid zymomonas mobilis 53.0 53.0 1 PMID:15930043 -4.1.1.1 2-ketovalerate zymomonas mobilis 13.7 13.7 1 PMID:10924138 -4.1.1.1 3-(indol-3-yl)pyruvate klebsiella pneumoniae 8.05 8.05 1 PMID:35501883 -4.1.1.1 pyruvate clostridium acetobutylicum 113.0 113.0 1 PMID:27800475 -4.1.1.1 pyruvate gluconobacter oxydans 125.0 47.0 3 PMID:24276622 -4.1.1.1 pyruvate klebsiella pneumoniae 0.58 0.58 1 PMID:35501883 -4.1.1.1 pyruvate kluyveromyces lactis 40.0 40.0 1 PMID:12084066 -4.1.1.1 pyruvate komagataella pastoris 8.6 8.6 1 PMID:23423327 -4.1.1.1 pyruvate nakaseomyces glabratus 77.0 60.3 2 PMID:15625313 -4.1.1.1 pyruvate neurospora crassa 18.3 15.45 6 PMID:22077835 -4.1.1.1 pyruvate saccharomyces cerevisiae 207.0 65.0 7 PMID:10433706;PMID:10433707;PMID:11327837;PMID:22300533;PMID:23423327 -4.1.1.1 pyruvate uncultured bacterium 580.0 580.0 1 PMID:29497023 -4.1.1.1 pyruvate zymomonas mobilis 486.0 135.0 4 PMID:10924138;PMID:11327837;PMID:15930043;PMID:20715795 -4.1.1.100 prephenate bacillus subtilis 3.2 3.2 1 PMID:20052993 -4.1.1.100 prephenate planktothrix agardhii 4.1 4.1 1 PMID:20863139 -4.1.1.102 4-coumarate saccharomyces cerevisiae 4.6 4.6 1 PMID:25647642 -4.1.1.102 4-hydroxycinnamic acid streptantibioticus cattleyicolor 0.19 0.19 1 PMID:25585255 -4.1.1.102 4-hydroxycinnamic acid streptomyces hygroscopicus 14.1 14.1 1 PMID:25585255 -4.1.1.102 4-hydroxycinnamic acid streptomyces sviceus 0.96 0.96 1 PMID:25585255 -4.1.1.102 ferulate enterobacter sp. 2.15 2.15 1 PMID:21283705 -4.1.1.102 ferulate saccharomyces cerevisiae 1.5 1.5 1 PMID:25647642 -4.1.1.102 trans-cinnamate saccharomyces cerevisiae 3.8 3.8 1 PMID:25647642 -4.1.1.103 2,3-dihydroxybenzoate polaromonas sp. js666 0.47 0.47 1 PMID:29283551 -4.1.1.103 2,4,6-trihydroxybenzoate polaromonas sp. js666 0.18 0.18 1 PMID:29283551 -4.1.1.103 2,6-dihydroxy-4-methylbenzoate polaromonas sp. js666 0.38 0.38 1 PMID:29283551 -4.1.1.103 2,6-dihydroxybenzoate agrobacterium tumefaciens 20.0 20.0 1 PMID:15474471 -4.1.1.103 2,6-dihydroxybenzoate polaromonas sp. js666 0.44 0.44 1 PMID:29283551 -4.1.1.103 5-methylresorcinol agrobacterium tumefaciens 4.98 4.98 1 * -4.1.1.103 catechol agrobacterium tumefaciens 0.141 0.141 1 * -4.1.1.103 gnetol agrobacterium tumefaciens 0.331 0.331 1 * -4.1.1.103 resorcinol agrobacterium tumefaciens 0.571 0.571 1 * -4.1.1.103 resveratrol agrobacterium tumefaciens 0.722 0.722 1 * -4.1.1.105 5-hydroxy-l-tryptophan gelatoporia subvermispora 0.17 0.17 2 PMID:26632772 -4.1.1.105 l-tryptophan catharanthus roseus 3.33 3.33 1 PMID:24310513 -4.1.1.105 l-tryptophan gelatoporia subvermispora 1.21 1.21 2 PMID:26632772 -4.1.1.105 l-tryptophan withania coagulans 1.66 1.66 1 PMID:26795344 -4.1.1.106 elaidic acid chlorella variabilis 0.45 0.45 1 PMID:34288332 -4.1.1.106 palmitate chlorella variabilis 1.64 1.08 3 PMID:32348726;PMID:34633183 -4.1.1.109 l-phenylalanine petunia x hybrida 0.8 0.8 2 PMID:16766535;PMID:30891451 -4.1.1.11 l-asp escherichia coli 0.57 0.57 1 PMID:9169598 -4.1.1.11 l-aspartate aedes aegypti 7.03 7.03 1 PMID:22685715 -4.1.1.11 l-aspartate bacillus subtilis 6.26 6.26 1 PMID:28589224 -4.1.1.11 l-aspartate corynebacterium jeikeium 6.92 6.92 1 PMID:30923994 -4.1.1.11 l-aspartate mycobacterium tuberculosis 0.65 0.65 1 PMID:12182836 -4.1.1.11 l-aspartate priestia aryabhattai 0.35 0.35 1 PMID:36708489 -4.1.1.11 l-aspartate pyrococcus furiosus 2.83 2.83 1 * -4.1.1.11 l-aspartate tribolium castaneum 16.9 10.01 2 PMID:31696283;PMID:32178239 -4.1.1.112 3-methyloxaloacetate pseudomonas aeruginosa 250.0 250.0 1 PMID:18081320 -4.1.1.112 oxaloacetate corynebacterium glutamicum 104.0 104.0 1 PMID:20233922 -4.1.1.112 oxaloacetate enterococcus faecalis 11.2 11.2 1 PMID:21518252 -4.1.1.112 oxaloacetate lactococcus lactis 20.26 11.88 2 PMID:15251467 -4.1.1.112 oxaloacetate pseudomonas aeruginosa 7500.0 7500.0 1 PMID:18081320 -4.1.1.115 (1h-indol-3-yl)acetate clostridium scatologenes 130.0 130.0 1 PMID:30310076 -4.1.1.115 (1h-indol-3-yl)acetate olsenella uli 11.8 11.8 1 PMID:35704859 -4.1.1.115 (1h-indol-3-yl)acetate tractidigestivibacter scatoligenes 2.0 2.0 1 PMID:30310076 -4.1.1.116 d-lysine salmonella enterica subsp. enterica serovar typhimurium 4.4 4.4 2 PMID:29024617 -4.1.1.116 d-ornithine salmonella enterica subsp. enterica serovar typhimurium 1.8 1.8 2 PMID:29024617 -4.1.1.12 (r)-3-benzyl-l-aspartate [pseudomonas] dacunhae 0.2 0.2 1 PMID:33094304 -4.1.1.12 l-alanine acinetobacter radioresistens 2680.0 2680.0 1 PMID:33760222 -4.1.1.12 l-asp comamonas testosteroni 442.0 442.0 1 PMID:19368885 -4.1.1.12 l-asp pseudomonas dacunhae 4.3 4.3 1 PMID:19265705 -4.1.1.12 l-aspartate [pseudomonas] dacunhae 1.5 1.5 1 * -4.1.1.12 l-aspartate acinetobacter radioresistens 884.63 884.615 2 * -4.1.1.12 l-aspartate mycobacterium tuberculosis 0.65 0.65 1 PMID:12182836 -4.1.1.127 n1-[(s)-3-amino-3-carboxypropyl]agmatine synechocystis sp. pcc 6803 2.36 2.36 1 PMID:37878710 -4.1.1.129 1'-carboxy-chondrochloren b chondromyces crocatus 0.258 0.258 1 PMID:20080978 -4.1.1.15 l-alpha-methylglutamate escherichia coli 9.53 9.53 1 * -4.1.1.15 l-glu felis catus 7.0 7.0 1 PMID:8080275 -4.1.1.15 l-glu homo sapiens 7.7 1.8 5 PMID:11543686 -4.1.1.15 l-glu levilactobacillus brevis 6.5 6.5 1 PMID:9255981 -4.1.1.15 l-glutamate bacillus 114.9 55.6 3 PMID:34348699 -4.1.1.15 l-glutamate brucella microti 17.88 17.88 1 PMID:25853037 -4.1.1.15 l-glutamate enterococcus faecium 0.43 0.43 1 * -4.1.1.15 l-glutamate escherichia coli 59.26 42.055 2 PMID:19797049;PMID:24480573 -4.1.1.15 l-glutamate lactiplantibacillus plantarum 25.4 25.4 1 PMID:33990858 -4.1.1.15 l-glutamate lactiplantibacillus plantarum subsp. plantarum 21.75 10.8825 2 PMID:25415663 -4.1.1.15 l-glutamate levilactobacillus brevis 102.1 51.193 2 PMID:23563537;PMID:32041144 -4.1.1.15 l-glutamate levilactobacillus senmaizukei 34.63 34.63 1 PMID:32464198 -4.1.1.15 l-glutamate pyrococcus furiosus 1.43 1.43 1 * -4.1.1.15 l-glutamate saccharomyces cerevisiae 0.537 0.537 1 PMID:28656550 -4.1.1.15 l-glutamate synechocystis sp. pcc 6803 100.7 100.7 1 PMID:26730883 -4.1.1.17 alpha-methylornithine lactobacillus sp. 30a 0.02 0.02 1 * -4.1.1.17 l-2,4-diaminobutanoate lacticaseibacillus casei 0.5 0.5 1 PMID:22247134 -4.1.1.17 l-2,4-diaminobutanoate lactobacillus gasseri 0.35 0.35 1 PMID:22247134 -4.1.1.17 l-2,4-diaminobutanoate levilactobacillus brevis 0.45 0.45 1 PMID:22247134 -4.1.1.17 l-2,4-diaminobutanoate oenococcus oeni 0.05 0.05 1 PMID:22247134 -4.1.1.17 l-arginine aspergillus terreus 3.4e-05 3.4e-05 1 PMID:31362455 -4.1.1.17 l-arginine caldisericum exile 0.11 0.11 1 PMID:34560100 -4.1.1.17 l-lysine aspergillus terreus 3.8e-05 3.8e-05 1 PMID:31362455 -4.1.1.17 l-lysine lactobacillus sp. 30a 2.04 2.04 1 PMID:30021117 -4.1.1.17 l-lysine levilactobacillus brevis 0.57 0.57 1 PMID:22247134 -4.1.1.17 l-lysine ligilactobacillus saerimneri 30a 0.25 0.25 1 PMID:23316036 -4.1.1.17 l-lysine nicotiana glutinosa 0.24 0.24 1 PMID:11736657 -4.1.1.17 l-lysine oenococcus oeni 0.09 0.09 1 PMID:22247134 -4.1.1.17 l-ornithine aspergillus terreus 4.3e-05 4.3e-05 1 PMID:31362455 -4.1.1.17 l-ornithine atropa belladonna 0.671 0.671 1 PMID:31935324 -4.1.1.17 l-ornithine clostridium botulinum 2.8 2.8 1 PMID:34560100 -4.1.1.17 l-ornithine erythroxylum coca 0.18 0.18 1 PMID:22311164 -4.1.1.17 l-ornithine escherichia coli 3.4 3.4 1 PMID:24706212 -4.1.1.17 l-ornithine fusobacterium necrophorum 1.1 1.1 1 PMID:34560100 -4.1.1.17 l-ornithine hyoscyamus niger 1.57 1.57 1 PMID:30873201 -4.1.1.17 l-ornithine lactobacillus gasseri 0.14 0.14 1 PMID:22247134 -4.1.1.17 l-ornithine lactobacillus sp. 30a 39.1 39.1 1 PMID:30021117 -4.1.1.17 l-ornithine levilactobacillus brevis 4.8 4.8 1 PMID:22247134 -4.1.1.17 l-ornithine ligilactobacillus saerimneri 30a 9.77 9.77 1 PMID:23316036 -4.1.1.17 l-ornithine nicotiana glutinosa 77.8 40.4 2 PMID:11736657 -4.1.1.17 l-ornithine oenococcus oeni 6.9 6.9 1 PMID:22247134 -4.1.1.17 l-ornithine plasmodium falciparum 0.006 0.0045000000000000005 2 PMID:11085920 -4.1.1.17 l-ornithine saccharomyces cerevisiae 4.2 3.75 2 PMID:21640851 -4.1.1.17 l-ornithine trypanosoma brucei 15.4 15.0 5 PMID:10512638;PMID:10985770;PMID:11683631;PMID:12627959;PMID:15476392;PMID:20220141 -4.1.1.18 l-2,4-diaminobutanoate streptomyces coelicolor 0.052 0.052 1 PMID:22906379 -4.1.1.18 l-lys hafnia alvei 175.0 175.0 1 * -4.1.1.18 l-lys selenomonas ruminantium 636.0 326.0 2 PMID:10427692;PMID:11073919 -4.1.1.18 l-lysine escherichia coli 146.4 88.2 2 PMID:21278708;PMID:28843030 -4.1.1.18 l-lysine hafnia alvei 4.12 4.12 1 * -4.1.1.18 l-lysine klebsiella aerogenes 0.98 0.98 1 PMID:27291676 -4.1.1.18 l-lysine leptospirillum ferriphilum 0.58 0.41 3 PMID:34560100 -4.1.1.18 l-lysine ligilactobacillus saerimneri 30a 1.68 1.68 1 PMID:23316036 -4.1.1.18 l-lysine vibrio vulnificus 1.58 1.58 1 PMID:30619163 -4.1.1.18 l-orn selenomonas ruminantium 289.8 149.20000000000002 2 PMID:10427692;PMID:11073919 -4.1.1.19 l-arg chlamydia trachomatis 6.9 6.9 1 PMID:19607664 -4.1.1.19 l-arg methanocaldococcus jannaschii 2.7 2.7 1 PMID:11980912 -4.1.1.19 l-arg yersinia pestis 5.46 5.46 1 PMID:14690429 -4.1.1.19 l-arginine acetivibrio thermocellus 0.05 0.05 1 PMID:34560100 -4.1.1.19 l-arginine avena sativa 9.9 5.4 2 PMID:19063883 -4.1.1.19 l-arginine bacillus cihuensis 1.1 1.1 1 PMID:34560100 -4.1.1.19 l-arginine bacillus subtilis 1.4 0.8049999999999999 2 PMID:20876533 -4.1.1.19 l-arginine chlamydia pneumoniae 6.9 6.9 1 PMID:17693492 -4.1.1.19 l-arginine chloroflexus aurantiacus 11.0 11.0 1 PMID:20876533 -4.1.1.19 l-arginine christiangramia forsetii 0.48 0.48 1 PMID:20876533 -4.1.1.19 l-arginine clostridioides difficile 0.025 0.025 1 PMID:20876533 -4.1.1.19 l-arginine helicobacter pylori 0.92 0.92 1 PMID:29684243 -4.1.1.19 l-arginine methanimicrococcus blatticola 0.36 0.36 1 PMID:34560100 -4.1.1.19 l-arginine peribacillus simplex 0.57 0.57 1 PMID:34560100 -4.1.1.19 l-arginine psychrilyobacter sp. s5 0.3 0.3 1 PMID:34560100 -4.1.1.19 l-arginine saccharolobus solfataricus 2.6 2.6 1 PMID:18650422 -4.1.1.19 l-arginine shewanella algae 12.62 12.62 1 PMID:34532832 -4.1.1.19 l-canavanine yersinia pestis 0.11 0.11 1 PMID:14690429 -4.1.1.19 l-n5-(iminoethyl)-ornithine yersinia pestis 0.419 0.419 1 PMID:14690429 -4.1.1.19 l-ornithine bacillus subtilis 0.04 0.04 1 PMID:20876533 -4.1.1.19 ngamma-methyl-l-arginine yersinia pestis 1.22 1.22 1 PMID:14690429 -4.1.1.2 oxalate bacillus subtilis 89.2 53.5 8 PMID:11546787;PMID:17459326;PMID:19473032;PMID:21434608;PMID:29620872;PMID:30806021;PMID:34097877 -4.1.1.2 oxalate lactiplantibacillus plantarum 64.0 64.0 1 * -4.1.1.2 oxalate pseudomonas sp. 206.0 206.0 1 PMID:35007451 -4.1.1.20 d,d-2,6-diaminoheptanedioate mycobacterium tuberculosis 1.8 1.8 1 PMID:21640851 -4.1.1.20 dd-2,6-diaminoheptanedioate mycobacterium tuberculosis 1.8 1.8 1 PMID:21640851 -4.1.1.20 dl-2,6-diaminoheptanedioate mycobacterium tuberculosis 7.1 7.1 1 PMID:21640851 -4.1.1.20 meso-2,6-diaminoheptanedioate arabidopsis thaliana 0.014 0.0095 2 PMID:30962284 -4.1.1.20 meso-2,6-diaminoheptanedioate bacillus anthracis 58.0 58.0 1 PMID:25986217;PMID:26921318 -4.1.1.20 meso-2,6-diaminoheptanedioate escherichia coli 55.0 55.0 1 PMID:25986217;PMID:26921318 -4.1.1.20 meso-2,6-diaminoheptanedioate helicobacter pylori 15.65 15.65 1 PMID:18508763 -4.1.1.20 meso-2,6-diaminoheptanedioate mycobacterium tuberculosis 8.0 7.1 3 PMID:21640851;PMID:25986217;PMID:26921318 -4.1.1.20 meso-2,6-diaminoheptanedioate thermotoga maritima 0.075 0.075 1 PMID:34258615 -4.1.1.20 meso-2,6-diaminoheptanedioate vibrio cholerae serotype o1 22.0 22.0 1 PMID:26921318 -4.1.1.21 1-(5-phosphoribosyl)-5-aminoimidazole gallus gallus 40.0 40.0 1 PMID:7918410 -4.1.1.21 4-carboxy-5-aminoimidazole ribonucleotide treponema denticola 65.0 40.5 2 PMID:21548610 -4.1.1.21 co2 treponema denticola 77.0 77.0 1 PMID:21548610 -4.1.1.22 l-histidine homo sapiens 1.73 1.73 2 PMID:22767596;PMID:28613002 -4.1.1.23 2'-deoxyorotidine 5'-phosphate saccharomyces cerevisiae 0.15 0.15 1 PMID:11371183 -4.1.1.23 4-thioorotidine 5'-phosphate saccharomyces cerevisiae 9.0 9.0 1 PMID:1457411 -4.1.1.23 5-azaorotidine 5'-phosphate saccharomyces cerevisiae 5.0 5.0 1 PMID:1457411 -4.1.1.23 5-fluoroorotidine 5'-phosphate saccharomyces cerevisiae 570.0 95.0 5 PMID:1457411;PMID:18081312;PMID:24053466;PMID:26135041;PMID:32374983 -4.1.1.23 orotidine 5'-monophosphate saccharomyces cerevisiae 15.0 15.0 1 PMID:18598058 -4.1.1.23 orotidine 5'-phosphate escherichia coli 42.0 25.0 2 PMID:10757968;PMID:21898650 -4.1.1.23 orotidine 5'-phosphate homo sapiens 8.1 4.425 2 PMID:18181562;PMID:18184586 -4.1.1.23 orotidine 5'-phosphate methanobacterium thermoautotrophicus 4.0 4.0 1 PMID:21870810 -4.1.1.23 orotidine 5'-phosphate methanothermobacter thermautotrophicus 21.0 20.7 3 PMID:16884305;PMID:18181562;PMID:23030629 -4.1.1.23 orotidine 5'-phosphate plasmodium falciparum 985.8 15.6 7 PMID:15147974;PMID:15683248;PMID:18181562;PMID:28389349 -4.1.1.23 orotidine 5'-phosphate saccharomyces cerevisiae 44.0 17.0 10 PMID:10446147;PMID:10995247;PMID:11278904;PMID:11371183;PMID:18081312;PMID:24053466;PMID:24958125;PMID:31365243;PMID:32374983 -4.1.1.25 l-dopa levilactobacillus brevis 159.0 117.75 2 PMID:27292129 -4.1.1.25 l-dopa rehmannia glutinosa 0.126 0.126 1 PMID:35268735 -4.1.1.25 l-tyrosine levilactobacillus brevis 343.0 165.0 3 PMID:24211777;PMID:27292129 -4.1.1.25 l-tyrosine pyrococcus furiosus 2.83 2.83 1 * -4.1.1.25 l-tyrosine rehmannia glutinosa 0.507 0.507 1 PMID:35268735 -4.1.1.28 2-fluoro-dopa sus scrofa 5.2 5.2 1 PMID:12083775 -4.1.1.28 5-fluoro-dopa sus scrofa 6.0 4.735 2 PMID:12083775 -4.1.1.28 5-hydroxy-l-tryptophan sus scrofa 0.67 0.67 1 PMID:18547057 -4.1.1.28 6-fluoro-dopa sus scrofa 8.2 8.2 1 PMID:12083775 -4.1.1.28 dopamine homo sapiens 2.48 2.48 1 PMID:19580779 -4.1.1.28 l-5-hydroxytryptophan sus scrofa 6.08 2.465 4 * -4.1.1.28 l-dopa homo sapiens 5.1 2.585 2 PMID:19580779;PMID:24407024 -4.1.1.28 l-dopa levilactobacillus brevis 159.0 159.0 1 * -4.1.1.28 l-dopa pseudomonas putida 1.8 1.8 1 PMID:23059975 -4.1.1.28 l-dopa rattus norvegicus 6.3 6.3 1 PMID:24407024 -4.1.1.28 l-dopa rehmannia glutinosa 0.126 0.126 1 PMID:35268735 -4.1.1.28 l-dopa sus scrofa 9.1 5.8 7 PMID:12083775;PMID:18547057;PMID:24407024 -4.1.1.28 l-phenylalanine bacillus atrophaeus 7.4 7.4 3 PMID:33713143 -4.1.1.28 l-phenylalanine psilocybe cubensis 9.68 9.68 1 PMID:30484626 -4.1.1.28 l-tryptophan bacillus atrophaeus 6.7 6.7 1 PMID:33713143 -4.1.1.28 l-tryptophan psilocybe cubensis 0.6 0.6 1 PMID:30484626 -4.1.1.28 l-tyrosine levilactobacillus brevis 165.0 165.0 1 * -4.1.1.28 l-tyrosine rehmannia glutinosa 0.507 0.507 1 PMID:35268735 -4.1.1.28 l-tyrosine solanum lycopersicum 0.7 0.7 1 PMID:16698923 -4.1.1.29 3-sulfino-l-alanine unidentified prokaryotic organism 0.763 0.763 1 PMID:29796005 -4.1.1.29 cysteine sulfinic acid tribolium castaneum 6.92 6.92 1 PMID:31696283 -4.1.1.29 l-cysteine sulfinate aedes aegypti 5.86 5.86 1 PMID:22685715 -4.1.1.31 hco3- echinochloa esculenta 57.3 57.3 1 PMID:33345397 -4.1.1.31 hco3- paspalum vaginatum 58.7 58.7 1 PMID:33345397 -4.1.1.31 phosphoenolpyruvate alternanthera ficoidea 33.0 33.0 2 PMID:16136331 -4.1.1.31 phosphoenolpyruvate alternanthera pungens 38.0 38.0 2 PMID:16136331 -4.1.1.31 phosphoenolpyruvate alternanthera sessilis 16.0 11.05 2 PMID:16136331 -4.1.1.31 phosphoenolpyruvate corynebacterium glutamicum 142.9 70.45500000000001 4 PMID:28256782 -4.1.1.31 phosphoenolpyruvate escherichia coli 540.0 540.0 1 PMID:9927652 -4.1.1.31 phosphoenolpyruvate sorghum bicolor 66.0 9.5 5 PMID:16624802 -4.1.1.31 phosphoenolpyruvate spinacia oleracea 69.0 56.0 2 PMID:4212347 -4.1.1.31 phosphoenolpyruvate synechocystis sp. pcc 6803 48.7 48.7 1 PMID:32274833 -4.1.1.32 2'-deoxyguanosine 5'-diphosphate ascaris suum 4.6 4.6 1 PMID:12127066 -4.1.1.32 2'-deoxyguanosine 5'-triphosphate ascaris suum 3.4 3.4 1 PMID:12127066 -4.1.1.32 co2 rattus norvegicus 19.0 19.0 1 PMID:20476774 -4.1.1.32 gdp ascaris suum 6.5 6.5 1 PMID:12127066 -4.1.1.32 gdp corynebacterium glutamicum 7.2 7.2 1 PMID:14550651 -4.1.1.32 gdp rattus norvegicus 19.0 19.0 1 PMID:20476774 -4.1.1.32 gtp ascaris suum 13.9 13.9 1 PMID:12127066 -4.1.1.32 gtp rattus norvegicus 54.0 54.0 1 PMID:20476774 -4.1.1.32 idp ascaris suum 6.9 6.9 1 PMID:12127066 -4.1.1.32 itp ascaris suum 15.6 15.6 1 PMID:12127066 -4.1.1.32 oxaloacetate ascaris suum 17.8 17.8 1 PMID:12127066 -4.1.1.32 oxaloacetate rattus norvegicus 54.0 54.0 1 PMID:20476774 -4.1.1.32 phosphoenolpyruvate ascaris suum 9.3 9.3 1 PMID:12127066 -4.1.1.32 phosphoenolpyruvate corynebacterium glutamicum 6.1 6.1 1 PMID:14550651 -4.1.1.32 phosphoenolpyruvate rattus norvegicus 19.0 19.0 1 PMID:20476774 -4.1.1.33 (3r)-3-cyclopropyl-3-hydroxy-5-[[hydroxy(phosphonooxy)phosphoryl]oxy]pentanoic acid streptococcus pneumoniae 0.27 0.27 1 PMID:20404339 -4.1.1.33 (3r)-3-ethyl-3-hydroxy-5-[[hydroxy(phosphonooxy)phosphoryl]oxy]pentanoic acid streptococcus pneumoniae 1.3 1.3 1 PMID:20404339 -4.1.1.33 (3r)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)-4-methylpentanoic acid streptococcus pneumoniae 0.018 0.018 1 PMID:20404339 -4.1.1.33 (3r)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)-5-methylhexanoic acid streptococcus pneumoniae 0.024 0.024 1 PMID:20404339 -4.1.1.33 (3r)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)hex-4-ynoic acid streptococcus pneumoniae 0.21 0.21 1 PMID:20404339 -4.1.1.33 (3r)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)hex-5-enoic acid streptococcus pneumoniae 0.39 0.39 1 PMID:20404339 -4.1.1.33 (3r)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)pent-4-enoic acid streptococcus pneumoniae 3.2 3.2 1 PMID:20404339 -4.1.1.33 (3r)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)pent-4-ynoic acid streptococcus pneumoniae 1.3 1.3 1 PMID:20404339 -4.1.1.33 (r)-5-diphosphomevalonate anaerolinea thermophila 0.74 0.74 1 PMID:31268677 -4.1.1.33 (r)-5-diphosphomevalonate bacopa monnieri 40.0 40.0 1 PMID:26027607 -4.1.1.33 (r)-5-diphosphomevalonate staphylococcus epidermidis 5.3 5.3 1 PMID:25499551 -4.1.1.33 (r,s)-5-diphosphomevalonate staphylococcus epidermidis 5.9 5.9 1 PMID:21561869 -4.1.1.33 5-diphosphomevalonate flavobacterium johnsoniae 18.5 18.5 1 PMID:28442346 -4.1.1.33 5-diphosphomevalonate homo sapiens 4.5 4.5 1 PMID:18823933 -4.1.1.33 5-diphosphomevalonate saccharomyces cerevisiae 4.9 4.9 1 PMID:15169949;PMID:15709780 -4.1.1.33 atp bacopa monnieri 30.0 30.0 1 PMID:26027607 -4.1.1.33 diphosphomevalonate streptococcus pneumoniae 5.6 5.6 1 PMID:20404339 -4.1.1.35 udp-d-glucuronate hordeum vulgare 2.7 2.7 1 PMID:15849307 -4.1.1.35 udp-d-glucuronate oryza sativa 1.69 0.9249999999999999 2 PMID:15488465 -4.1.1.36 (r)-4'-phospho-n-pantothenoylcysteine homo sapiens 2.9 2.9 1 PMID:15581364 -4.1.1.37 uroporphyrinogen-i homo sapiens 0.124 0.124 1 PMID:19656450 -4.1.1.37 uroporphyrinogen-iii homo sapiens 0.317 0.317 1 PMID:19656450 -4.1.1.39 co2 acidovorax facilis 1.04 1.04 1 PMID:805894 -4.1.1.39 co2 acrosiphonia arcta 5.08 2.95 2 PMID:30576461 -4.1.1.39 co2 agriophyllum squarrosum 5.1 2.8 3 PMID:27342312 -4.1.1.39 co2 agrostis scabra 5.0 3.6 3 PMID:27342312 -4.1.1.39 co2 agrostis stolonifera 7.8 5.2 3 PMID:27342312 -4.1.1.39 co2 alaria esculenta 2.13 1.18 2 PMID:30576461 -4.1.1.39 co2 allochromatium vinosum 6.7 6.7 1 PMID:16641091 -4.1.1.39 co2 amaranthus hybridus 3.8 3.8 1 PMID:16641091 -4.1.1.39 co2 amphicarpaea bracteata 6.1 4.0 3 PMID:27342312 -4.1.1.39 co2 anethum foeniculum 7.3 4.4 3 PMID:27342312 -4.1.1.39 co2 arabidopsis thaliana 3.31 3.11 3 PMID:36124740 -4.1.1.39 co2 arctagrostis latifolia 8.7 5.8 3 PMID:27342312 -4.1.1.39 co2 artemisia myriantha 7.8 3.1 3 PMID:27342312 -4.1.1.39 co2 artemisia vulgaris 7.4 3.9 3 PMID:27342312 -4.1.1.39 co2 beta vulgaris 5.9 3.8 3 PMID:27342312 -4.1.1.39 co2 blitum petiolare 6.0 4.4 3 PMID:27342312 -4.1.1.39 co2 bromus anomalus 4.6 2.9 3 PMID:27342312 -4.1.1.39 co2 calamagrostis arundinacea 4.7 4.1 3 PMID:27342312 -4.1.1.39 co2 calamagrostis canescens 5.2 2.5 3 PMID:27342312 -4.1.1.39 co2 calamagrostis foliosa 4.7 3.5 3 PMID:27342312 -4.1.1.39 co2 calamagrostis nutkaensis 4.5 3.1 3 PMID:27342312 -4.1.1.39 co2 calamagrostis stricta subsp. inexpansa 4.2 3.3 3 PMID:27342312 -4.1.1.39 co2 chenopodiastrum murale 5.4 4.4 3 PMID:27342312 -4.1.1.39 co2 chlamydomonas reinhardtii 5.8 5.8 1 PMID:16641091 -4.1.1.39 co2 chrysanthellum indicum 7.0 4.7 3 PMID:27342312 -4.1.1.39 co2 citrullus ecirrhosus 5.5 3.1 3 PMID:27342312 -4.1.1.39 co2 citrullus lanatus 4.0 2.5 3 PMID:27342312 -4.1.1.39 co2 cupriavidus necator 1.38 1.38 1 PMID:805894 -4.1.1.39 co2 cylindrotheca fusiformis 1.95 1.95 1 PMID:8031129 -4.1.1.39 co2 cylindrotheca sp. 0.78 0.78 1 PMID:8031129 -4.1.1.39 co2 deschampsia danthonioides 6.2 4.5 3 PMID:27342312 -4.1.1.39 co2 desmarestia aculeata 1.37 0.7450000000000001 2 PMID:30576461 -4.1.1.39 co2 desmodium cinereum 4.6 3.0 3 PMID:27342312 -4.1.1.39 co2 desmodium intortum 5.8 3.3 3 PMID:27342312 -4.1.1.39 co2 desmodium psilocarpum 5.3 3.6 3 PMID:27342312 -4.1.1.39 co2 devaleraea ramentacea 2.59 1.4649999999999999 2 PMID:30576461 -4.1.1.39 co2 elymus farctus 4.5 3.3 3 PMID:27342312 -4.1.1.39 co2 eragrostis tef 12.2 7.1 3 PMID:27342312 -4.1.1.39 co2 erythrina flabelliformis 5.9 3.6 3 PMID:27342312 -4.1.1.39 co2 euphorbia helioscopia 3.6 1.9 3 PMID:27342312 -4.1.1.39 co2 euphorbia microsphaera 6.2 4.5 3 PMID:27342312 -4.1.1.39 co2 festuca pratensis 8.7 5.1 3 PMID:27342312 -4.1.1.39 co2 flueggea suffruticosa 4.7 3.4 3 PMID:27342312 -4.1.1.39 co2 galdieria sulphuraria 1.2 1.2 2 PMID:16641091;PMID:20067527 -4.1.1.39 co2 glycine canescens 4.0 2.6 3 PMID:27342312 -4.1.1.39 co2 glycine max 4.1 2.0 4 PMID:27329223;PMID:27342312 -4.1.1.39 co2 griffithsia monilis 2.6 2.6 2 PMID:16641091;PMID:20067527 -4.1.1.39 co2 himantothallus grandifolius 2.08 1.155 2 PMID:30576461 -4.1.1.39 co2 hordeum brachyantherum 5.1 2.9 3 PMID:27342312 -4.1.1.39 co2 hordeum murinum 6.0 4.2 3 PMID:27342312 -4.1.1.39 co2 hordeum vulgare 2.4 2.4 1 PMID:27329223 -4.1.1.39 co2 lablab purpureus 6.5 5.3 3 PMID:27342312 -4.1.1.39 co2 lactuca sativa 2.2 2.2 1 PMID:27329223 -4.1.1.39 co2 laminaria digitata 1.42 0.76 2 PMID:30576461 -4.1.1.39 co2 laminaria solidungula 1.6 0.885 2 PMID:30576461 -4.1.1.39 co2 lepidium campestre 5.0 3.4 3 PMID:27342312 -4.1.1.39 co2 lolium giganteum 8.4 5.8 3 PMID:27342312 -4.1.1.39 co2 lolium multiflorum 6.9 4.5 3 PMID:27342312 -4.1.1.39 co2 lolium rigidum 7.0 4.7 3 PMID:27342312 -4.1.1.39 co2 macrotyloma uniflorum 7.2 4.4 3 PMID:27342312 -4.1.1.39 co2 manihot esculenta 4.5 2.4 3 PMID:27342312 -4.1.1.39 co2 mercurialis annua 4.6 3.4 3 PMID:27342312 -4.1.1.39 co2 musa velutina 3.8 3.2 3 PMID:27342312 -4.1.1.39 co2 nicotiana tabacum 6.4 3.4 20 PMID:16641091;PMID:19233903;PMID:20067527;PMID:27342312;PMID:32929197 -4.1.1.39 co2 olisthodiscus luteus 0.83 0.83 1 PMID:8031129 -4.1.1.39 co2 oryza barthii x oryza glaberrima 4.4 2.5 3 PMID:27342312 -4.1.1.39 co2 oryza eichingeri 4.2 2.5 3 PMID:27342312 -4.1.1.39 co2 oryza glaberrima 4.2 2.7 3 PMID:27342312 -4.1.1.39 co2 oryza glumipatula 3.7 2.4 3 PMID:27342312 -4.1.1.39 co2 oryza longistaminata 3.7 2.2 3 PMID:27342312 -4.1.1.39 co2 oryza meridionalis 4.2 2.6 3 PMID:27342312 -4.1.1.39 co2 oryza nivara 4.2 2.7 3 PMID:27342312 -4.1.1.39 co2 oryza punctata 4.8 2.7 3 PMID:27342312 -4.1.1.39 co2 oryza sativa 2.1 2.1 1 PMID:27329223 -4.1.1.39 co2 oryza sativa indica group 4.5 2.2 3 PMID:27342312 -4.1.1.39 co2 oryza sativa japonica group 4.9 2.8 3 PMID:27342312 -4.1.1.39 co2 oxybasis rubra 5.6 4.1 3 PMID:27342312 -4.1.1.39 co2 palmaria decipiens 2.43 1.37 2 PMID:30576461 -4.1.1.39 co2 palmaria palmata 2.08 1.175 2 PMID:30576461 -4.1.1.39 co2 panicum amarum 5.3 3.2 3 PMID:27342312 -4.1.1.39 co2 panicum dichotomiflorum 6.1 3.1 3 PMID:27342312 -4.1.1.39 co2 panicum phragmitoides 4.2 2.8 3 PMID:27342312 -4.1.1.39 co2 phaeodactylum tricornutum 3.4 3.4 2 PMID:16641091;PMID:20067527 -4.1.1.39 co2 phaseolus carteri 5.3 3.2 3 PMID:27342312 -4.1.1.39 co2 phaseolus coccineus 5.7 3.9 3 PMID:27342312 -4.1.1.39 co2 phaseolus lunatus 5.6 3.2 3 PMID:27342312 -4.1.1.39 co2 phaseolus vulgaris 5.7 3.5 3 PMID:27342312 -4.1.1.39 co2 phycodrys rubens 1.76 0.95 2 PMID:30576461 -4.1.1.39 co2 poa palustris 6.6 4.2 3 PMID:27342312 -4.1.1.39 co2 porphyridium purpureum 1.59 1.59 1 PMID:8031129 -4.1.1.39 co2 ptilota gunneri 1.6 0.885 2 PMID:30576461 -4.1.1.39 co2 puccinellia distans 8.1 5.4 3 PMID:27342312 -4.1.1.39 co2 puccinellia lemmonii 7.4 5.2 3 PMID:27342312 -4.1.1.39 co2 puccinellia maritima 7.8 5.4 3 PMID:27342312 -4.1.1.39 co2 puccinellia nuttalliana 4.8 4.4 3 PMID:27342312 -4.1.1.39 co2 pueraria montana 4.9 2.7 3 PMID:27342312 -4.1.1.39 co2 rhodospirillum rubrum 12.3 5.640000000000001 6 PMID:16641091;PMID:18004873;PMID:19231887;PMID:20060808;PMID:20067527;PMID:805894 -4.1.1.39 co2 saccharina latissima 1.79 0.975 2 PMID:30576461 -4.1.1.39 co2 sorghum bicolor 5.4 2.52 5 PMID:16641091;PMID:21562335 -4.1.1.39 co2 sphenostylis stenocarpa 4.2 2.8 3 PMID:27342312 -4.1.1.39 co2 spinacia oleracea 3.7 3.7 1 PMID:16641091 -4.1.1.39 co2 synechococcus 4.9 4.9 1 PMID:19705820 -4.1.1.39 co2 synechococcus sp. 13.9 12.5 4 PMID:16641091;PMID:20067527;PMID:8031129 -4.1.1.39 co2 tephrosia candida 4.2 2.2 3 PMID:27342312 -4.1.1.39 co2 tephrosia purpurea 3.7 2.2 3 PMID:27342312 -4.1.1.39 co2 tephrosia rhodesica 4.5 2.2 3 PMID:27342312 -4.1.1.39 co2 thermococcus kodakarensis 0.31 0.28 2 PMID:17675435;PMID:20926376 -4.1.1.39 co2 thermosynechococcus vestitus 9.5 7.9 16 PMID:17922215;PMID:28986448 -4.1.1.39 co2 thiobacillus denitrificans 3.5 2.7 2 PMID:8550452 -4.1.1.39 co2 triticum aestivum 6.9 2.9 7 PMID:16641091;PMID:20002330;PMID:27342312;PMID:30576461 -4.1.1.39 co2 triticum monococcum subsp. aegilopoides 6.3 3.8 3 PMID:27342312 -4.1.1.39 co2 zea mays 4.7 4.4 3 PMID:16641091;PMID:20002330;PMID:27329223 -4.1.1.39 d-ribulose 1,5-bisphosphate agave victoriae-reginae 3.4 3.4 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate arabidopsis thaliana 4.1 4.1 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate archaeoglobus fulgidus 23.1 23.1 2 PMID:17074752;PMID:26381513 -4.1.1.39 d-ribulose 1,5-bisphosphate atrichum undulatum 3.0 3.0 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate carpobrotus edulis 3.6 3.6 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate ceratophyllum demersum 3.5 3.5 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate crithmum maritimum 3.4 3.4 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate cycas panzhihuaensis 3.1 3.1 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate dactylis glomerata 3.4 3.2 3 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate drosera capensis 4.7 4.7 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate drosera venusta 3.3 3.3 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate echeveria elegans 4.5 4.5 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate eucalyptus moorei 3.2 3.2 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate eucalyptus neglecta 2.5 2.5 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate flaveria angustifolia 2.77 2.77 1 PMID:25663529 -4.1.1.39 d-ribulose 1,5-bisphosphate flaveria bidentis 3.42 3.42 1 PMID:25663529 -4.1.1.39 d-ribulose 1,5-bisphosphate flaveria cronquistii 2.95 2.95 1 PMID:25663529 -4.1.1.39 d-ribulose 1,5-bisphosphate flaveria floridana 2.86 2.86 1 PMID:25663529 -4.1.1.39 d-ribulose 1,5-bisphosphate flaveria pringlei 2.48 2.48 1 PMID:25663529 -4.1.1.39 d-ribulose 1,5-bisphosphate flaveria trinervia 3.28 3.28 1 PMID:25663529 -4.1.1.39 d-ribulose 1,5-bisphosphate galdieria sulphuraria 1.2 1.2 1 PMID:20067527 -4.1.1.39 d-ribulose 1,5-bisphosphate griffithsia monilis 2.6 2.6 1 PMID:20067527 -4.1.1.39 d-ribulose 1,5-bisphosphate iris douglasiana 3.5 3.5 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate limonium gibertii 2.5 2.5 1 PMID:25113451 -4.1.1.39 d-ribulose 1,5-bisphosphate limonium latebracteatum 2.7 2.7 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate limonium stenophyllum 2.6 2.6 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate limonium virgatum 2.4 2.4 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate marchantia polymorpha 2.6 2.6 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate metasequoia glyptostroboides 2.7 2.7 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate methanococcoides burtonii 4.0 2.4 2 PMID:19837658 -4.1.1.39 d-ribulose 1,5-bisphosphate nicotiana tabacum 3.4 3.3 2 PMID:20067527;PMID:25113451 -4.1.1.39 d-ribulose 1,5-bisphosphate nymphaea alba 2.4 2.4 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate pallenis maritima 2.7 2.7 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate phaeodactylum tricornutum 3.4 3.4 1 PMID:20067527 -4.1.1.39 d-ribulose 1,5-bisphosphate platycerium superbum 2.3 2.3 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate pteridium aquilinum 4.0 4.0 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate rhodospirillum rubrum 6.28 5.0 3 PMID:19231887;PMID:20060808;PMID:20067527 -4.1.1.39 d-ribulose 1,5-bisphosphate sarracenia flava 4.4 4.4 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate sideritis cretica subsp. spicata 2.0 2.0 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate synechococcus 4.9 4.9 1 PMID:19705820 -4.1.1.39 d-ribulose 1,5-bisphosphate synechococcus elongatus pcc 6301 4.3 4.3 1 PMID:31337726 -4.1.1.39 d-ribulose 1,5-bisphosphate synechococcus sp. 13.9 8.7 2 PMID:15067012;PMID:20067527 -4.1.1.39 d-ribulose 1,5-bisphosphate synechocystis sp. 14.28 11.68 2 PMID:15937184;PMID:21551078 -4.1.1.39 d-ribulose 1,5-bisphosphate teucrium heterophyllum 2.7 2.7 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate thermococcus kodakarensis 16.6 16.6 1 PMID:26381513 -4.1.1.39 d-ribulose 1,5-bisphosphate trachycarpus fortunei 2.8 2.8 1 PMID:24689692 -4.1.1.39 d-ribulose 1,5-bisphosphate triticum aestivum 5.5 4.0 3 PMID:24689692;PMID:25113451 -4.1.1.39 d-ribulose-1,5-bisphosphate griffithsia monilis 2.6 2.6 1 PMID:12781767 -4.1.1.39 d-ribulose-1,5-bisphosphate synechococcus sp. 3.5 3.5 1 PMID:12899828 -4.1.1.39 o2 nicotiana tabacum 0.42 0.42 1 PMID:19233903 -4.1.1.39 o2 rhodospirillum rubrum 1.4 1.4 1 PMID:18004873 -4.1.1.39 o2 thermococcus kodakarensis 0.38 0.38 1 PMID:17675435 -4.1.1.39 o2 triticum aestivum 0.83 0.83 1 PMID:20002330 -4.1.1.39 o2 zea mays 0.49 0.49 1 PMID:20002330 -4.1.1.39 ribulose-1,5-bisphosphate nicotiana tabacum 3.4 3.4 1 PMID:12781767 -4.1.1.39 ribulose-1,5-bisphosphate rhodospirillum rubrum 7.3 7.3 1 PMID:12781767 -4.1.1.4 (3e,5e)-2-oxo-6-phenylhexa-3,5-dienoate streptomyces bingchenggensis 1.57 1.335 2 PMID:31524380 -4.1.1.4 (3e,5e)-6-(4-nitrophenyl)-2-oxohexa-3,5-dienoate streptomyces bingchenggensis 1.9 1.29 2 PMID:31524380 -4.1.1.4 (3e,5e)-6-(furan-2-yl)-2-hydroxyhexa-3,5-dienoic acid streptomyces bingchenggensis 0.21 0.21 1 PMID:31524380 -4.1.1.4 2-methoxycinnamaldehyde streptomyces bingchenggensis 15.7 15.7 1 PMID:31524380 -4.1.1.4 2-methyl-trans-cinnamaldehyde streptomyces bingchenggensis 2.0 2.0 1 PMID:31524380 -4.1.1.4 2-nitro cinnamaldehyde streptomyces bingchenggensis 24.7 24.7 1 PMID:31524380 -4.1.1.4 3-(2-furyl)acrolein streptomyces bingchenggensis 22.9 22.9 1 PMID:31524380 -4.1.1.4 3-(3-pyridyl)acrolein streptomyces bingchenggensis 221.9 221.9 1 PMID:31524380 -4.1.1.4 3-methoxy-4-hydroxycinnamaldehyde streptomyces bingchenggensis 1.7 1.7 1 PMID:31524380 -4.1.1.4 4-methoxycinnamaldehyde streptomyces bingchenggensis 3.3 3.3 1 PMID:31524380 -4.1.1.4 4-nitro cinnamaldehyde streptomyces bingchenggensis 10.2 8.25 2 PMID:31524380 -4.1.1.4 acetoacetate chromobacterium violaceum 349.0 349.0 1 PMID:19458715 -4.1.1.4 acetoacetate clostridium acetobutylicum 1560.0 862.5 2 PMID:19458715;PMID:8555196 -4.1.1.4 benzofuran-2-carbaldehyde streptomyces bingchenggensis 7.3 7.3 1 PMID:31524380 -4.1.1.4 benzylidenepyruvate streptomyces bingchenggensis 1.2 1.2 1 PMID:31524380 -4.1.1.4 pyruvate streptomyces bingchenggensis 22.3 22.3 1 PMID:31524380 -4.1.1.4 trans-cinnamaldehyde streptomyces bingchenggensis 28.3 25.65 2 PMID:31524380 -4.1.1.43 (indol-3-yl)pyruvate enterobacter sp. cgmcc 5087 3.7 3.7 1 PMID:35377224 -4.1.1.43 2-ketohexanoic acid azospirillum brasilense 0.29 0.29 1 PMID:17766418 -4.1.1.43 2-oxo-4-phenylbutanoic acid saccharomyces cerevisiae 1.7 1.7 1 PMID:21501384 -4.1.1.43 2-oxobutanoate enterobacter sp. cgmcc 5087 185.8 185.8 1 PMID:35377224 -4.1.1.43 2-oxobutanoic acid saccharomyces cerevisiae 3.9 3.9 1 PMID:21501384 -4.1.1.43 2-oxohexanoate enterobacter sp. cgmcc 5087 74.8 74.8 1 PMID:35377224 -4.1.1.43 2-oxohexanoic acid saccharomyces cerevisiae 8.8 8.8 1 PMID:21501384 -4.1.1.43 2-oxopentanoate enterobacter sp. cgmcc 5087 128.8 128.8 1 PMID:35377224 -4.1.1.43 2-oxopentanoic acid saccharomyces cerevisiae 5.2 5.2 1 PMID:21501384 -4.1.1.43 3-methyl-2-oxobutanoate enterobacter sp. cgmcc 5087 34.9 34.9 1 PMID:35377224 -4.1.1.43 3-methyl-2-oxobutanoic acid saccharomyces cerevisiae 19.0 19.0 1 PMID:21501384 -4.1.1.43 3-methyl-2-oxopentanoate enterobacter sp. cgmcc 5087 29.4 29.4 1 PMID:35377224 -4.1.1.43 3-methyl-2-oxopentanoic acid saccharomyces cerevisiae 11.0 11.0 1 PMID:21501384 -4.1.1.43 4-hydroxyphenylpyruvate saccharomyces cerevisiae 11.0 11.0 1 PMID:21501384 -4.1.1.43 4-methyl-2-oxopentanoic acid saccharomyces cerevisiae 10.0 10.0 1 PMID:21501384 -4.1.1.43 4-methylthio-2-oxobutanoic acid saccharomyces cerevisiae 7.7 7.7 1 PMID:21501384 -4.1.1.43 4-phenyl-2-oxobutanoic acid azospirillum brasilense 0.21 0.21 1 PMID:17766418 -4.1.1.43 5-phenyl-2-oxopentanoic acid azospirillum brasilense 1.7 1.7 1 PMID:17766418 -4.1.1.43 indole-3-pyruvate azospirillum brasilense 0.07 0.07 1 PMID:17766418 -4.1.1.43 indole-3-pyruvate saccharomyces cerevisiae 5.4 5.4 1 PMID:21501384 -4.1.1.43 phenylpyruvate azospirillum brasilense 5.56 5.56 1 PMID:17766418 -4.1.1.43 phenylpyruvate enterobacter sp. cgmcc 5087 186.9 186.9 1 PMID:35377224 -4.1.1.43 phenylpyruvate saccharomyces cerevisiae 20.0 20.0 1 PMID:21501384 -4.1.1.43 phenylpyruvate streptomyces virginiae 0.0055 0.0055 1 PMID:28719183 -4.1.1.43 pyruvic acid saccharomyces cerevisiae 0.34 0.34 1 PMID:21501384 -4.1.1.45 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate pseudomonas fluorescens 6.5 6.5 1 PMID:24019523 -4.1.1.45 2-amino-3-(3-oxoprop-2-enyl)-but-2-enedioate homo sapiens 1.0 1.0 1 PMID:17288562 -4.1.1.45 2-amino-3-(3-oxoprop-2-enyl)-but-2-enedioate pseudomonas fluorescens 7.3 6.65 3 PMID:16716073;PMID:16939194 -4.1.1.45 2-aminomuconate semialdehyde homo sapiens 4.8 2.4499999999999997 2 PMID:25392945 -4.1.1.45 alpha-amino-beta-carboxymuconate-epsilon-semialdehyde pseudomonas fluorescens 10.2 4.5 4 PMID:16131206 -4.1.1.46 2,3-dihydroxybenzoate fusarium odoratissimum nrrl 54006 27.17 27.17 1 PMID:29602385 -4.1.1.46 2,3-dihydroxybenzoate klebsiella pneumoniae 0.065 0.065 1 PMID:25045104 -4.1.1.46 catechol fusarium odoratissimum nrrl 54006 0.78 0.78 1 PMID:29602385 -4.1.1.47 glyoxylate escherichia coli k-12 18.9 18.9 1 PMID:18176558 -4.1.1.48 1-(2-carboxyphenylamino)-1-deoxy-d-ribulose 5-phosphate escherichia coli 9.3 4.1 3 PMID:22274606;PMID:8747456 -4.1.1.48 1-(2-carboxyphenylamino)-1-deoxy-d-ribulose 5-phosphate mycobacterium tuberculosis 0.16 0.16 1 PMID:19364491 -4.1.1.48 1-(2-carboxyphenylamino)-1-deoxy-d-ribulose 5-phosphate pseudomonas aeruginosa 11.1 11.1 1 PMID:22555873 -4.1.1.48 1-(2-carboxyphenylamino)-1-deoxy-d-ribulose 5-phosphate pyrococcus furiosus 8.4 8.4 1 PMID:30264228 -4.1.1.48 1-(2-carboxyphenylamino)-1-deoxy-d-ribulose 5-phosphate saccharolobus solfataricus 2.1 0.29 8 PMID:23214473;PMID:23900843;PMID:24403092;PMID:29498826;PMID:8747456 -4.1.1.48 1-(2-carboxyphenylamino)-1-deoxy-d-ribulose-5-phosphate escherichia coli 7.2 3.6 5 PMID:2494074;PMID:7727400;PMID:9091315 -4.1.1.48 1-(2-carboxyphenylamino)-1-deoxy-d-ribulose-5-phosphate pseudomonas aeruginosa 3.0 3.0 1 PMID:32928960 -4.1.1.48 1-(2-carboxyphenylamino)-1-deoxy-d-ribulose-5-phosphate saccharolobus solfataricus 3.15 0.0915 6 PMID:10653631;PMID:16342933;PMID:7947963;PMID:9091315 -4.1.1.48 1-(2-carboxyphenylamino)-1-deoxy-d-ribulose-5-phosphate thermotoga maritima 0.095 0.095 1 PMID:16342933 -4.1.1.48 1-(phenylamino)-1-deoxy-d-ribulose-5-phosphate pseudomonas aeruginosa 0.0044 0.0044 1 PMID:32928960 -4.1.1.49 (z)-3-fluorophosphoenolpyruvate anaerobiospirillum succiniciproducens 0.33 0.33 1 PMID:18675879 -4.1.1.49 (z)-3-fluorophosphoenolpyruvate saccharomyces cerevisiae 1.1 1.1 1 PMID:18675879 -4.1.1.49 adp leishmania major 78.82 78.82 1 PMID:26271440 -4.1.1.49 adp saccharomyces cerevisiae 62.0 62.0 1 PMID:20524049 -4.1.1.49 atp leishmania major 48.09 48.09 1 PMID:26271440 -4.1.1.49 atp saccharomyces cerevisiae 38.0 38.0 1 PMID:20524049 -4.1.1.49 oxalacetate saccharomyces cerevisiae 65.0 32.66 2 PMID:18996167 -4.1.1.49 oxaloacetate escherichia coli 0.433 0.433 1 PMID:31911238 -4.1.1.49 oxaloacetate leishmania major 51.54 51.54 1 PMID:26271440 -4.1.1.49 oxaloacetate saccharomyces cerevisiae 0.28 0.28 1 PMID:20211682 -4.1.1.49 phosphoenolpyruvate anaerobiospirillum succiniciproducens 22.0 15.835 2 PMID:18675879;PMID:8436945 -4.1.1.49 phosphoenolpyruvate escherichia coli 0.67 0.67 1 PMID:23683699 -4.1.1.49 phosphoenolpyruvate leishmania major 65.52 65.52 1 PMID:26271440 -4.1.1.49 phosphoenolpyruvate saccharomyces cerevisiae 63.0 53.0 5 PMID:18346928;PMID:18675879;PMID:18996167;PMID:20211682 -4.1.1.5 (2s)-2-hydroxy-2-methyl-3-oxobutanoate enterobacter cloacae 0.96 0.96 1 PMID:35558320 -4.1.1.5 (2s)-2-hydroxy-2-methyl-3-oxobutanoate klebsiella aerogenes 0.81 0.81 1 PMID:31000168 -4.1.1.5 (s)-2-hydroxy-2-methyl-3-oxobutanoate leuconostoc lactis 66.67 33.685 2 PMID:11164316 -4.1.1.5 2-hydroxy-2-methyl-3-oxobutanoate lacticaseibacillus casei 5.57 5.57 1 * -4.1.1.5 dl-2-hydroxy-2-methyl-3-oxobutanoate bacillus subtilis 2.2 2.2 1 PMID:29796971 -4.1.1.50 s-adenosyl-l-methionine methanocaldococcus jannaschii 0.0075 0.0075 1 PMID:14573607 -4.1.1.50 s-adenosyl-l-methionine plasmodium falciparum 0.088 0.088 1 PMID:21803076 -4.1.1.50 s-adenosyl-l-methionine streptomyces griseochromogenes 0.027 0.027 1 PMID:23874663 -4.1.1.50 s-adenosyl-l-methionine thermotoga maritima 1.0 1.0 1 PMID:20124698 -4.1.1.50 s-adenosyl-l-methionine trypanosoma brucei 1.7 0.007350000000000001 6 PMID:17485680;PMID:23288847 -4.1.1.50 s-adenosyl-methionine trypanosoma cruzi 6.0 6.0 1 PMID:10727226 -4.1.1.51 3-hydroxy-2-methylpyridine-4,5-dicarboxylate mesorhizobium loti 0.6 0.6 1 PMID:17973403 -4.1.1.57 l-met dryopteris filix-mas 100.0 75.0 2 PMID:2271523 -4.1.1.57 l-met streptomyces sp. 120.0 120.0 1 PMID:2271525 -4.1.1.57 l-methionine streptomyces sp. 590 ki-2014 239.0 147.6 2 PMID:28003434;PMID:33452696 -4.1.1.57 l-norleucine streptomyces sp. 590 ki-2014 61.0 61.0 1 PMID:28003434 -4.1.1.59 gallic acid blastobotrys adeninivorans 42.0 42.0 1 PMID:28966611 -4.1.1.59 protocatechuic acid blastobotrys adeninivorans 44.0 44.0 1 PMID:28966611 -4.1.1.6 cis-aconitate aspergillus terreus 18.4 18.4 2 PMID:31548418 -4.1.1.6 cis-aconitate homo sapiens 0.94 0.94 2 PMID:31548418 -4.1.1.6 cis-aconitate mus musculus 4.94 4.94 2 PMID:31548418 -4.1.1.61 3,4-dihydroxybenzoate sedimentibacter hydroxybenzoicus 18.3 18.3 1 PMID:7744052 -4.1.1.61 4-hydroxybenzoate sedimentibacter hydroxybenzoicus 55.0 55.0 1 PMID:7744052 -4.1.1.63 3,4-dihydroxybenzoate sedimentibacter hydroxybenzoicus 90.0 90.0 1 PMID:8655551 -4.1.1.64 1-amino-1-cyclohexanecarboxylate burkholderia cepacia 2.3 2.3 1 PMID:9521707 -4.1.1.64 1-amino-1-cyclopentanecarboxylate burkholderia cepacia 0.98 0.98 1 PMID:9521707 -4.1.1.64 2-aminoisobutanoate burkholderia cepacia 25.0 4.135 14 PMID:15109259;PMID:9521707;PMID:9548963 -4.1.1.64 alpha-aminomalonate burkholderia cepacia 0.025 0.025 1 PMID:9521707 -4.1.1.64 d-ala burkholderia cepacia 0.2 0.2 1 PMID:9521707 -4.1.1.64 gly burkholderia cepacia 0.0012 0.0012 1 PMID:9521707 -4.1.1.64 l-ala burkholderia cepacia 0.033 0.033 1 PMID:9521707 -4.1.1.7 2-ketobutanoate pseudomonas putida 4.0 4.0 1 PMID:19621900 -4.1.1.7 2-ketohexanoate pseudomonas putida 5.3 5.3 1 PMID:19621900 -4.1.1.7 2-ketopentanoate pseudomonas putida 11.0 11.0 1 PMID:19621900 -4.1.1.7 2-oxo-4-methylhexanoic acid pseudomonas putida 8.6 8.6 1 PMID:15930043 -4.1.1.7 2-oxo-4-methylpentanoic acid pseudomonas putida 11.0 11.0 1 PMID:15930043 -4.1.1.7 2-oxobutanoate pseudomonas putida 7.5 7.5 1 * -4.1.1.7 2-oxobutanoic acid pseudomonas putida 17.3 17.3 1 PMID:15930043 -4.1.1.7 2-oxohexanoate mycolicibacterium smegmatis 20.0 20.0 1 PMID:25936776 -4.1.1.7 2-oxohexanoate pseudomonas putida 4.1 4.1 1 * -4.1.1.7 2-oxohexanoic acid pseudomonas putida 21.0 21.0 1 PMID:15930043 -4.1.1.7 2-oxopentanoate pseudomonas putida 6.0 6.0 1 * -4.1.1.7 2-oxopentanoic acid pseudomonas putida 44.3 44.3 1 PMID:15930043 -4.1.1.7 4-methyl-2-oxopentanoate pseudomonas putida 11.0 11.0 1 * -4.1.1.7 4-methylthio-2-oxobutanoate mycolicibacterium smegmatis 20.0 20.0 1 PMID:25936776 -4.1.1.7 4-methylthio-2-oxobutanoate pseudomonas putida 4.5 4.5 1 * -4.1.1.7 benzoylformate mycolicibacterium smegmatis 5.1 5.1 1 PMID:25936776 -4.1.1.7 benzoylformate pseudomonas putida 1349.0 320.0 5 PMID:12590569;PMID:15930043;PMID:18398009;PMID:19182954 -4.1.1.7 benzoylformate stutzerimonas stutzeri 284.0 253.0 2 PMID:17916405 -4.1.1.7 benzylformate pseudomonas putida 320.0 320.0 1 PMID:19621900 -4.1.1.7 p-nitro-benzoylformate pseudomonas putida 0.05 0.05 1 PMID:19182954 -4.1.1.7 phenylglyoxylate pseudomonas putida 320.0 320.0 1 PMID:23895593 -4.1.1.71 2-oxoglutarate picosynechococcus sp. pcc 7002 1.2 1.2 2 PMID:29574001 -4.1.1.72 (indol-3-yl)pyruvate mycobacterium tuberculosis 2.98 2.98 1 PMID:18086676 -4.1.1.72 2-oxo-3-methylpentanoate mycobacterium tuberculosis 19.75 19.75 1 PMID:18086676 -4.1.1.72 2-oxobutyrate mycobacterium tuberculosis 5.98 5.98 1 PMID:18086676 -4.1.1.72 2-oxohexanoate mycobacterium tuberculosis 7.06 7.06 1 PMID:18086676 -4.1.1.72 2-oxoisohexanoate mycobacterium tuberculosis 31.5 31.5 1 PMID:18086676 -4.1.1.72 2-oxoisopentanoate mycobacterium tuberculosis 28.35 28.35 1 PMID:18086676 -4.1.1.72 2-oxoisovalerate bacillus subtilis 8.9 8.9 1 PMID:19684168 -4.1.1.72 2-oxoisovalerate homo sapiens 0.19 0.19 2 PMID:15166214 -4.1.1.72 2-oxopentanoate mycobacterium tuberculosis 6.95 6.95 1 PMID:18086676 -4.1.1.72 3-methyl-2-oxobutanoate lactococcus lactis 145.0 145.0 1 PMID:29953730 -4.1.1.72 3-methyl-2-oxobutanoate thermoplasma acidophilum 0.3 0.3 1 PMID:15556640 -4.1.1.72 3-methyl-2-oxobutyrate psychrobacter arcticus 29.0 29.0 1 PMID:23826991 -4.1.1.72 3-methyl-2-oxobutyrate psychrobacter cryohalolentis 33.0 33.0 1 PMID:23826991 -4.1.1.72 3-methyl-2-oxopentanoate lactococcus lactis 25.0 25.0 1 PMID:23826991 -4.1.1.72 3-methyl-2-oxopentanoate psychrobacter arcticus 23.0 23.0 1 PMID:23826991 -4.1.1.72 3-methyl-2-oxopentanoate psychrobacter cryohalolentis 27.0 27.0 1 PMID:23826991 -4.1.1.72 3-methyl-2-oxopentanoate thermoplasma acidophilum 0.5 0.5 1 PMID:15556640 -4.1.1.72 4-hydroxyphenylpyruvate mycobacterium tuberculosis 3.89 3.89 1 PMID:18086676 -4.1.1.72 4-methyl-2-oxopentanoate psychrobacter arcticus 7.0 7.0 1 PMID:23826991 -4.1.1.72 4-methyl-2-oxopentanoate psychrobacter cryohalolentis 8.5 8.5 1 PMID:23826991 -4.1.1.72 4-methyl-2-oxopentanoate thermoplasma acidophilum 0.17 0.17 1 PMID:15556640 -4.1.1.72 benzoylformate mycobacterium tuberculosis 18.57 18.57 1 PMID:18086676 -4.1.1.72 phenylpyruvate mycobacterium tuberculosis 7.5 7.5 1 PMID:18086676 -4.1.1.72 phenylpyruvate psychrobacter arcticus 1.7 1.7 1 PMID:23826991 -4.1.1.72 phenylpyruvate psychrobacter cryohalolentis 1.8 1.8 1 PMID:23826991 -4.1.1.72 pyruvate mycobacterium tuberculosis 2.14 2.14 1 PMID:18086676 -4.1.1.72 pyruvate thermoplasma acidophilum 0.09 0.09 1 PMID:15556640 -4.1.1.72 thiamine diphosphate homo sapiens 0.19 0.19 2 PMID:15166214 -4.1.1.74 3-(indol-3-yl)pyruvate enterobacter cloacae 0.98 0.98 1 PMID:15835904 -4.1.1.74 3-(indol-3-yl)pyruvate klebsiella pneumoniae 8.05 8.05 1 PMID:35501883 -4.1.1.74 3-(indol-3-yl)pyruvate methylorubrum extorquens 0.64 0.64 1 PMID:21314613 -4.1.1.74 4-hydroxyphenylpyruvate methylorubrum extorquens 1.65 1.65 1 PMID:21314613 -4.1.1.74 benzoylformate methylorubrum extorquens 31.4 31.4 1 PMID:21314613 -4.1.1.74 benzoylformic acid enterobacter cloacae 11.6 11.6 1 PMID:15835904 -4.1.1.74 pyruvate enterobacter cloacae 0.88 0.88 1 PMID:15835904 -4.1.1.74 pyruvate klebsiella pneumoniae 0.58 0.58 1 PMID:35501883 -4.1.1.74 pyruvate methylorubrum extorquens 0.89 0.89 1 PMID:21314613 -4.1.1.75 5-guanidino-2-oxopentanoate pseudomonas putida 167.0 167.0 1 PMID:237915 -4.1.1.76 (1-benzofuran-2-yl)(hydroxy)propanedioic acid bordetella bronchiseptica 277.9 277.9 1 PMID:25766433 -4.1.1.76 (1-benzothiophen-5-yl)(hydroxy)propanedioic acid bordetella bronchiseptica 147.7 147.7 1 PMID:25766433 -4.1.1.76 (1-benzothiophen-6-yl)(hydroxy)propanedioic acid bordetella bronchiseptica 147.7 147.7 1 PMID:25766433 -4.1.1.76 (1e)-but-1-en-1-yl(methyl)propanedioic acid bordetella bronchiseptica 23.9 23.9 1 PMID:19739187 -4.1.1.76 (4,5-dimethylfuran-2-yl)(hydroxy)propanedioic acid bordetella bronchiseptica 12.4 12.4 1 PMID:25766433 -4.1.1.76 (furan-2-yl)(hydroxy)propanedioic acid bordetella bronchiseptica 61.9 61.9 1 PMID:25766433 -4.1.1.76 1-naphthylmalonate bordetella bronchiseptica 576.0 576.0 1 PMID:1459132 -4.1.1.76 2-hydroxy-2-phenylmalonic acid bordetella bronchiseptica 101.0 101.0 1 PMID:19739187 -4.1.1.76 2-methyl-2-phenylmalonate bordetella bronchiseptica 279.0 279.0 1 PMID:18576402 -4.1.1.76 2-methyl-2-phenylmalonate chelativorans sp. bnc1 55.8 55.8 1 PMID:18576402 -4.1.1.76 2-naphthylmalonate bordetella bronchiseptica 1730.0 1730.0 1 PMID:1459132 -4.1.1.76 2-phenyl-2-methylmalonate bordetella bronchiseptica 358.0 337.0 2 PMID:20135034 -4.1.1.76 2-phenylmalonate bordetella bronchiseptica 260.0 260.0 1 PMID:21559536 -4.1.1.76 2-thienylmalonate bordetella bronchiseptica 5320.0 5320.0 1 PMID:1459132 -4.1.1.76 2-vinyl-2-methylmalonic acid bordetella bronchiseptica 42.8 42.8 1 PMID:19739187 -4.1.1.76 alpha-methyl-alpha(2-thienyl)malonate bordetella bronchiseptica 200.0 200.0 1 PMID:1459132 -4.1.1.76 alpha-methyl-alpha-(alpha-thienyl)malonate bordetella bronchiseptica 200.0 200.0 2 PMID:16865343 -4.1.1.76 alpha-methyl-alpha-(beta-naphthyl)malonate bordetella bronchiseptica 30.9 30.9 2 PMID:16865343 -4.1.1.76 alpha-methyl-alpha-phenylmalonate bordetella bronchiseptica 29.8 29.8 1 PMID:1459132 -4.1.1.76 alpha-phenylmalonate bordetella bronchiseptica 366.0 366.0 1 * -4.1.1.76 hydroxy(2-methylprop-1-en-1-yl)propanedioic acid bordetella bronchiseptica 20.7 20.7 1 PMID:19739187 -4.1.1.76 hydroxy(4-methylfuran-2-yl)propanedioic acid bordetella bronchiseptica 42.4 42.4 1 PMID:25766433 -4.1.1.76 hydroxy(5-methoxyfuran-2-yl)propanedioic acid bordetella bronchiseptica 30.5 30.5 1 PMID:25766433 -4.1.1.76 hydroxy(5-methylfuran-2-yl)propanedioic acid bordetella bronchiseptica 37.1 37.1 1 PMID:25766433 -4.1.1.76 hydroxy(phenyl)propanedioic acid bordetella bronchiseptica 101.0 101.0 1 PMID:25766433 -4.1.1.76 hydroxy(pyridin-3-yl)propanedioic acid bordetella bronchiseptica 224.8 224.8 2 PMID:25766433 -4.1.1.76 hydroxy(thiophen-2-yl)propanedioic acid bordetella bronchiseptica 165.9 165.9 2 PMID:25766433 -4.1.1.76 hydroxy[(1e)-prop-1-en-1-yl]propanedioic acid bordetella bronchiseptica 47.6 47.6 1 PMID:19739187 -4.1.1.76 m-chlorophenylmalonate bordetella bronchiseptica 1420.0 1420.0 1 PMID:1459132 -4.1.1.76 m-fluorophenylmalonate bordetella bronchiseptica 2180.0 2180.0 1 PMID:1459132 -4.1.1.76 methyl(2-methylprop-1-en-1-yl)propanedioic acid bordetella bronchiseptica 5.2 5.2 1 PMID:19739187 -4.1.1.76 methyl(2-naphthyl)malonic acid bordetella bronchiseptica 31.0 31.0 1 PMID:15700067 -4.1.1.76 methyl(2-thienyl)malonic acid bordetella bronchiseptica 200.0 200.0 1 PMID:15700067 -4.1.1.76 methyl(phenyl)propanedioic acid bordetella bronchiseptica 279.0 279.0 1 PMID:19739187 -4.1.1.76 methyl[(1e)-prop-1-en-1-yl]propanedioic acid bordetella bronchiseptica 46.2 46.2 1 PMID:19739187 -4.1.1.76 o-chlorophenylmalonate bordetella bronchiseptica 1090.0 1090.0 1 PMID:1459132 -4.1.1.76 o-fluorophenylmalonate bordetella bronchiseptica 666.0 666.0 1 PMID:1459132 -4.1.1.76 p-chlorophenylmalonate bordetella bronchiseptica 782.0 782.0 1 PMID:1459132 -4.1.1.76 p-fluorophenylmalonate bordetella bronchiseptica 195.0 195.0 1 PMID:1459132 -4.1.1.76 p-methoxyphenylmalonate bordetella bronchiseptica 92.0 92.0 1 PMID:1459132 -4.1.1.76 p-methylphenylmalonate bordetella bronchiseptica 125.0 125.0 1 PMID:1459132 -4.1.1.76 phenylmalonate alkaliphilus metalliredigens qymf 0.26 0.26 1 PMID:18576402 -4.1.1.76 phenylmalonate bordetella bronchiseptica 353.0 316.0 3 PMID:1459132;PMID:18576402;PMID:19739187 -4.1.1.76 phenylmalonate chelativorans sp. bnc1 118.0 118.0 1 PMID:18576402 -4.1.1.76 phenylmalonate pyrococcus horikoshii 0.09 0.09 1 PMID:18576402 -4.1.1.77 (3e)-2-oxohex-3-enedioate pseudomonas putida 108.4 98.8 5 PMID:27082660 -4.1.1.77 2-oxo-3-hexenedioate pseudomonas putida 68.0 68.0 1 PMID:10651637 -4.1.1.77 4-oxalocrotonate pseudomonas putida 68.0 68.0 1 PMID:15301547 -4.1.1.8 oxalyl-coa escherichia coli 60.7 60.7 1 PMID:20553497 -4.1.1.8 oxalyl-coa methylorubrum extorquens 98.0 98.0 1 PMID:31894608 -4.1.1.8 oxalyl-coa oxalobacter formigenes 88.0 88.0 2 PMID:16216870;PMID:17637344 -4.1.1.82 3-phosphonopyruvate bacteroides fragilis 10.2 10.149999999999999 2 PMID:12904299;PMID:28693916 -4.1.1.82 3-phosphonopyruvate streptomyces viridochromogenes 1.18 1.18 1 * -4.1.1.83 (4-hydroxyphenyl)acetate clostridioides difficile 110.0 110.0 1 PMID:16878993 -4.1.1.83 (4-hydroxyphenyl)acetate clostridium scatologenes 135.0 135.0 1 PMID:16878993 -4.1.1.83 3,4-dihydroxyphenylacetate clostridioides difficile 65.0 65.0 1 PMID:16878993 -4.1.1.83 3,4-dihydroxyphenylacetate clostridium scatologenes 67.0 67.0 1 PMID:16878993 -4.1.1.83 4-hydroxyphenylacetate tractidigestivibacter scatoligenes 21.9 21.9 1 * -4.1.1.84 4-chlorophenylpyruvate homo sapiens 68.0 68.0 1 PMID:35041425 -4.1.1.84 4-hydroxyphenylpyruvate homo sapiens 13.0 13.0 1 PMID:35041425 -4.1.1.84 4-methoxyphenylpyruvate homo sapiens 8.0 8.0 1 PMID:35041425 -4.1.1.84 phenylpyruvate homo sapiens 132.0 132.0 1 PMID:35041425 -4.1.1.85 3-dehydro-l-gulonate 6-phosphate escherichia coli k-12 64.0 51.0 3 PMID:11741871;PMID:15157077;PMID:15697206 -4.1.1.85 3-dehydro-l-gulonate 6-phosphate methylomonas aminofaciens 15.0 15.0 1 PMID:15697206 -4.1.1.86 l-2,4-diaminobutanoate trichormus variabilis 0.34 0.34 1 PMID:22906379 -4.1.1.86 l-2,4-diaminobutyrate vibrio cholerae serotype o1 8.3 8.3 1 PMID:19196710 -4.1.1.86 l-lysine trichormus variabilis 0.008 0.008 1 PMID:22906379 -4.1.1.86 l-ornithine vibrio cholerae serotype o1 0.54 0.54 1 PMID:19196710 -4.1.1.9 malonyl-coa homo sapiens 141.2 118.75 6 PMID:15003260;PMID:18294446;PMID:23482565 -4.1.1.9 n-hydroxy-l-ornithine saccharopolyspora erythraea 0.038 0.038 1 PMID:21650455 -4.1.1.90 co2 bos taurus 1.0 1.0 1 PMID:8473318 -4.1.1.90 fleel bos taurus 1.7 0.7 5 PMID:8063763;PMID:8663364 -4.1.1.90 fleel homo sapiens 0.21 0.05665 4 PMID:12968027 -4.1.1.90 vitamin kh2 bos taurus 0.66 0.34 2 PMID:8663364 -4.1.1.90 yvfldhqdadanlilnrpkr bos taurus 0.488 0.324 5 PMID:8663364 -4.1.1.91 2,3-dihydroxybenzoate cutaneotrichosporon moniliiforme 21.0 21.0 1 PMID:34553918 -4.1.1.91 2,4-dihydroxybenzoate cutaneotrichosporon moniliiforme 13.0 13.0 1 PMID:34553918 -4.1.1.91 2,6-dihydroxybenzoate cutaneotrichosporon moniliiforme 2.1 2.1 1 PMID:34553918 -4.1.1.91 ginkgolic acid c15:1 cutaneotrichosporon moniliiforme 0.0135 0.0135 1 PMID:36527585 -4.1.1.91 phenol cutaneotrichosporon moniliiforme 1.1 1.1 1 PMID:20188702 -4.1.1.91 salicylate cutaneotrichosporon moniliiforme 3.6 1.817 2 PMID:20188702;PMID:34553918 -4.1.1.94 (s)-ethylmalonyl-coa mus musculus 10.0 9.75 2 PMID:22016388 -4.1.1.94 methylmalonyl-coa mus musculus 1.81 1.71 2 PMID:22016388 -4.1.1.96 carboxynorspermidine campylobacter jejuni 0.58 0.58 1 PMID:20534592 -4.1.1.96 carboxynorspermidine vibrio vulnificus 20.1 20.1 1 PMID:19196710 -4.1.1.96 carboxyspermidine campylobacter jejuni 0.24 0.24 1 PMID:20534592 -4.1.1.96 carboxyspermidine eshraghiella crossota 4.31 4.31 1 PMID:35931895 -4.1.1.96 carboxyspermidine vibrio vulnificus 3.2 3.2 1 PMID:19196710 -4.1.1.99 (r)-5-phosphomevalonate anaerolinea thermophila 1.6 1.6 1 PMID:31268677 -4.1.2.10 (r)-4-methylsulfanylbenzaldehyde prunus dulcis 142.0 89.65 4 * -4.1.2.10 (r)-mandelonitrile chamberlinius hualienensis 142.0 142.0 1 PMID:32679618 -4.1.2.10 (r)-mandelonitrile davallia tyermanii 356.0 214.0 4 PMID:28466867 -4.1.2.10 (r)-mandelonitrile eriobotrya japonica 56.0 56.0 1 PMID:18540101 -4.1.2.10 (r)-mandelonitrile granulicella tundricola 0.03 0.03 1 PMID:23981508 -4.1.2.10 (r)-mandelonitrile prunus armeniaca 1130.4 1130.4 1 * -4.1.2.10 (r)-mandelonitrile prunus dulcis 818.0 598.5 4 * -4.1.2.10 (r)-mandelonitrile prunus pedunculata 676.5 676.5 1 PMID:29890248 -4.1.2.10 1-naphthaldehyde parafontaria laminata 68.3 68.3 1 PMID:33163773 -4.1.2.10 2,4-dimethylbenzaldehyde chamberlinius hualienensis 300.0 300.0 1 PMID:26261304 -4.1.2.10 2,4-dimethylbenzaldehyde parafontaria laminata 85.0 85.0 1 PMID:33163773 -4.1.2.10 2-chlorobenzaldehyde parafontaria laminata 378.0 378.0 1 PMID:33163773 -4.1.2.10 2-methylbenzaldehyde parafontaria laminata 520.0 520.0 1 PMID:33163773 -4.1.2.10 2-naphthaldehyde eriobotrya japonica 1160.0 1160.0 1 PMID:18540101 -4.1.2.10 2-naphthaldehyde parafontaria laminata 220.0 220.0 1 PMID:33163773 -4.1.2.10 2-thiophenecarboxaldehyde chamberlinius hualienensis 1490.0 1490.0 1 PMID:26261304 -4.1.2.10 3-methoxybenzaldehyde chamberlinius hualienensis 1680.0 1680.0 1 PMID:26261304 -4.1.2.10 3-methoxybenzaldehyde parafontaria laminata 13800.0 13800.0 1 PMID:33163773 -4.1.2.10 3-methylbenzaldehyde chamberlinius hualienensis 6890.0 6890.0 1 PMID:26261304 -4.1.2.10 3-methylbenzaldehyde parafontaria laminata 417.0 417.0 1 PMID:33163773 -4.1.2.10 4-anisaldehyde parafontaria laminata 378.0 378.0 1 PMID:33163773 -4.1.2.10 4-biphenylcarboxaldehyde chamberlinius hualienensis 49.0 49.0 1 PMID:26261304 -4.1.2.10 4-biphenylcarboxaldehyde parafontaria laminata 833.0 833.0 1 PMID:33163773 -4.1.2.10 4-bromobenzaldehyde chamberlinius hualienensis 8610.0 8610.0 1 PMID:26261304 -4.1.2.10 4-bromobenzaldehyde parafontaria laminata 416.0 416.0 1 PMID:33163773 -4.1.2.10 4-methoxybenzaldehyde chamberlinius hualienensis 3480.0 3480.0 1 PMID:26261304 -4.1.2.10 4-methylbenzaldehyde chamberlinius hualienensis 5520.0 5520.0 1 PMID:26261304 -4.1.2.10 4-methylbenzaldehyde parafontaria laminata 320.0 320.0 1 PMID:33163773 -4.1.2.10 benzaldehyde chamberlinius hualienensis 3390.0 2750.0 2 PMID:26261304;PMID:32679618 -4.1.2.10 benzaldehyde eriobotrya japonica 1700.0 1700.0 1 PMID:18540101 -4.1.2.10 benzaldehyde parafontaria laminata 694.0 694.0 1 PMID:33163773 -4.1.2.10 benzaldehyde passiflora edulis 63.1 38.7 12 PMID:27914120;PMID:31562666 -4.1.2.10 benzaldehyde prunus armeniaca 43.3 43.3 1 * -4.1.2.10 isobutyraldehyde eriobotrya japonica 110.0 110.0 1 PMID:18540101 -4.1.2.10 p-anisaldehyde eriobotrya japonica 582.0 582.0 1 PMID:18540101 -4.1.2.10 piperonal eriobotrya japonica 334.0 334.0 1 PMID:18540101 -4.1.2.10 pivaldehyde eriobotrya japonica 164.0 164.0 1 PMID:18540101 -4.1.2.10 propionaldehyde eriobotrya japonica 223.0 223.0 1 PMID:18540101 -4.1.2.13 d-fructose 1,6-bisphosphate bacillus cereus 2.95 2.95 1 PMID:21763425 -4.1.2.13 d-fructose 1,6-bisphosphate bacillus methanolicus 5.1 3.3499999999999996 2 PMID:23760818 -4.1.2.13 d-fructose 1,6-bisphosphate candida albicans 38.6 38.6 1 PMID:35099959 -4.1.2.13 d-fructose 1,6-bisphosphate daucus carota 64.5 64.5 1 PMID:2198022 -4.1.2.13 d-fructose 1,6-bisphosphate edwardsiella ictaluri 13.0 13.0 1 PMID:15531627 -4.1.2.13 d-fructose 1,6-bisphosphate escherichia coli 14.2 10.5 3 PMID:10712619;PMID:11779234;PMID:15531627;PMID:9878448 -4.1.2.13 d-fructose 1,6-bisphosphate gallus gallus 45.9 45.9 1 PMID:14698918 -4.1.2.13 d-fructose 1,6-bisphosphate giardia duodenalis 3.55 3.55 2 PMID:17166851;PMID:19236002 -4.1.2.13 d-fructose 1,6-bisphosphate helicobacter pylori 1.0 1.0 1 PMID:29593097 -4.1.2.13 d-fructose 1,6-bisphosphate homo sapiens 59.7 5.2 11 PMID:12417303;PMID:12464284;PMID:14766013;PMID:15537755;PMID:7982900 -4.1.2.13 d-fructose 1,6-bisphosphate leishmania mexicana 8.2 8.2 1 PMID:10551371 -4.1.2.13 d-fructose 1,6-bisphosphate lethenteron camtschaticum 49.3 32.0 4 PMID:9143366 -4.1.2.13 d-fructose 1,6-bisphosphate methylococcus capsulatus 0.055 0.018 3 PMID:20673213 -4.1.2.13 d-fructose 1,6-bisphosphate mycobacterium tuberculosis 30.1 25.55 2 PMID:15294302;PMID:21763425 -4.1.2.13 d-fructose 1,6-bisphosphate neisseria meningitidis 2.1 2.1 1 PMID:20199602 -4.1.2.13 d-fructose 1,6-bisphosphate oryctolagus cuniculus 42.2 5.17 10 PMID:11779856;PMID:12611890;PMID:17935305;PMID:1857377;PMID:19354220;PMID:33210455 -4.1.2.13 d-fructose 1,6-bisphosphate pseudomonas aeruginosa 1.53 1.53 1 PMID:21763425 -4.1.2.13 d-fructose 1,6-bisphosphate pyricularia grisea 46.0 45.85 2 PMID:16901716;PMID:21763425 -4.1.2.13 d-fructose 1,6-bisphosphate rattus norvegicus 33.0 33.0 1 PMID:7982900 -4.1.2.13 d-fructose 1,6-bisphosphate staphylococcus aureus 13.9 7.5 5 PMID:1857377;PMID:25390935 -4.1.2.13 d-fructose 1,6-bisphosphate staphylococcus carnosus 20.3 18.53 2 PMID:20198665 -4.1.2.13 d-fructose 1,6-bisphosphate sulfurisphaera tokodaii 0.027 0.027 1 PMID:21983966 -4.1.2.13 d-fructose 1,6-bisphosphate toxoplasma gondii 7.09 7.09 2 PMID:28972169 -4.1.2.13 d-fructose 1,6-bisphosphate trypanosoma brucei 10.9 7.790000000000001 4 PMID:1857377;PMID:7756837 -4.1.2.13 d-fructose 1,6-bisphosphate vigna radiata 40.0 40.0 1 PMID:15896364 -4.1.2.13 d-fructose 1-phosphate homo sapiens 6.08 0.67 7 PMID:12417303;PMID:12464284;PMID:15537755 -4.1.2.13 d-fructose 1-phosphate oryctolagus cuniculus 6.08 3.355 4 PMID:12611890;PMID:17935305 -4.1.2.13 d-fructose-1,6-bisphosphate mycobacterium tuberculosis 12.0 12.0 1 PMID:23298222 -4.1.2.13 d-glyceraldehyde 3-phosphate bacillus methanolicus 12.6 6.58 2 PMID:23760818 -4.1.2.13 d-glyceraldehyde 3-phosphate methylococcus capsulatus 0.002 0.002 1 PMID:20673213 -4.1.2.13 d-glyceraldehyde 3-phosphate sulfurisphaera tokodaii 0.91 0.91 1 PMID:21983966 -4.1.2.13 dihydroxyacetone phosphate methylococcus capsulatus 0.002 0.002 1 PMID:20673213 -4.1.2.13 fructose 1-phosphate homo sapiens 10.8 1.48 3 PMID:7982900 -4.1.2.13 fructose 1-phosphate lethenteron camtschaticum 3.65 2.575 4 PMID:9143366 -4.1.2.13 fructose 1-phosphate oryctolagus cuniculus 0.267 0.183 3 PMID:1857377 -4.1.2.13 fructose 1-phosphate rattus norvegicus 2.67 2.67 1 PMID:7982900 -4.1.2.13 fructose 1-phosphate staphylococcus aureus 1.05 0.583 3 PMID:1857377 -4.1.2.13 fructose 1-phosphate trypanosoma brucei 1.7 1.27 3 PMID:1857377 -4.1.2.13 glycerone phosphate bacillus methanolicus 8.0 4.2 2 PMID:23760818 -4.1.2.13 glycerone phosphate sulfurisphaera tokodaii 0.91 0.91 1 PMID:21983966 -4.1.2.13 sedoheptulose 1,7-bisphosphate methylococcus capsulatus 0.003 0.003 1 PMID:20673213 -4.1.2.13 sedoheptulose 1,7-diphosphate daucus carota 25.2 25.2 1 PMID:2198022 -4.1.2.13 sedoheptulose 7-phosphate vigna radiata 33.3 33.3 1 PMID:15896364 -4.1.2.14 (4s)-2-oxo-4-hydroxy-4-(2'-pyridyl)butanoate escherichia coli 11.0 11.0 1 PMID:22316217 -4.1.2.14 2-dehydro-3-deoxy-6-phospho-d-gluconate escherichia coli 83.0 83.0 1 PMID:22316217 -4.1.2.14 2-dehydro-3-deoxy-d-gluconate escherichia coli 6.08 0.14500000000000002 12 PMID:11094340;PMID:17962400 -4.1.2.14 2-dehydro-3-deoxy-d-gluconate 6-phosphate escherichia coli 284.0 66.0 10 PMID:11094340;PMID:17962400;PMID:17981470 -4.1.2.14 2-dehydro-3-deoxy-d-gluconate 6-phosphate thermotoga maritima 3.9 2.0 3 PMID:11814840 -4.1.2.14 2-dehydro-4-hydroxy-4-(2'-pyridyl)butyrate escherichia coli 11.0 11.0 1 PMID:17962400 -4.1.2.14 2-dehydro-4-hydroxyoctonate escherichia coli 2.0 2.0 1 PMID:17962400 -4.1.2.14 2-keto-3-deoxy-6-phosphogluconate thermotoga maritima 80.0 80.0 1 PMID:17062752 -4.1.2.14 4-hydroxy-2-oxooctonate escherichia coli 2.0 2.0 1 PMID:22316217 -4.1.2.14 6-phospho-2-dehydro-3-deoxy-d-gluconate pseudomonas fluorescens 533.0 533.0 1 PMID:14245411 -4.1.2.14 pyruvate escherichia coli 0.0121 0.0121 1 PMID:11342129 -4.1.2.17 dihydroxyacetone phosphate escherichia coli 19.3 9.83 2 PMID:19115296 -4.1.2.17 l-fuculose 1-phosphate escherichia coli 19.0 19.0 1 PMID:11054289 -4.1.2.19 dihydroxyacetone phosphate escherichia coli 9.1 9.1 1 PMID:19115296 -4.1.2.19 l-rhamnulose 1-phosphate escherichia coli 38.3 38.3 1 PMID:4975916 -4.1.2.19 l-rhamnulose 1-phosphate thermotoga maritima 2.52 2.52 1 PMID:25324130 -4.1.2.20 2-dehydro-3-deoxy-6-phospho-d-gluconate picrophilus oshimae 0.34 0.34 1 PMID:20023024 -4.1.2.20 2-dehydro-3-deoxy-d-gluconate picrophilus oshimae 26.7 26.7 1 PMID:20023024 -4.1.2.20 2-dehydro-3-deoxy-l-rhamnonic acid escherichia coli 0.4 0.4 1 PMID:18754683 -4.1.2.20 2-keto-3-deoxy-l-lyxonate escherichia coli 0.3 0.3 1 PMID:18754683 -4.1.2.20 2-keto-3-deoxy-l-mannonate escherichia coli 0.3 0.3 1 PMID:18754683 -4.1.2.20 4-hydroxy-2-ketoheptane-1,7-dioate escherichia coli 299.0 149.77 2 PMID:18754683 -4.1.2.20 4-hydroxy-2-ketohexanoic acid escherichia coli 447.0 447.0 1 PMID:18754683 -4.1.2.20 4-hydroxy-2-ketopentanoic acid escherichia coli 396.0 396.0 1 PMID:18754683 -4.1.2.20 5-dehydro-4-deoxy-d-glucarate escherichia coli 27.3 27.3 1 PMID:9772162 -4.1.2.21 d-erythrose 4-phosphate escherichia coli 0.94 0.94 1 PMID:17451239 -4.1.2.22 d-fructose 6-phosphate bifidobacterium breve 25.7 25.685000000000002 2 PMID:20693675;PMID:20739284 -4.1.2.22 d-fructose 6-phosphate lactiplantibacillus plantarum 1.05 1.05 1 PMID:25605308 -4.1.2.22 d-fructose 6-phosphate lactococcus lactis 117.76 117.76 1 PMID:24740691 -4.1.2.22 d-fructose 6-phosphate lactococcus lactis subsp. lactis 117.8 117.8 1 PMID:24740691 -4.1.2.22 d-fructose 6-phosphate leuconostoc mesenteroides 44.23 44.23 1 PMID:24740691 -4.1.2.22 d-fructose 6-phosphate leuconostoc mesenteroides subsp. mesenteroides 44.2 44.2 1 PMID:24740691 -4.1.2.22 d-fructose 6-phosphate pseudomonas aeruginosa 13.1 13.075 2 PMID:24740691 -4.1.2.22 d-xylulose 5-phosphate lactococcus lactis 587.76 587.76 1 PMID:24740691 -4.1.2.22 d-xylulose 5-phosphate lactococcus lactis subsp. lactis 587.8 587.8 1 PMID:24740691 -4.1.2.22 d-xylulose 5-phosphate leuconostoc mesenteroides 431.78 431.78 1 PMID:24740691 -4.1.2.22 d-xylulose 5-phosphate leuconostoc mesenteroides subsp. mesenteroides 431.8 431.8 1 PMID:24740691 -4.1.2.22 d-xylulose 5-phosphate pseudomonas aeruginosa 13.2 13.19 2 PMID:24740691 -4.1.2.22 phosphate bifidobacterium breve 25.7 25.7 1 PMID:20693675 -4.1.2.22 phosphate lactiplantibacillus plantarum 1.12 1.12 1 PMID:25605308 -4.1.2.23 l-arabinose escherichia coli 7.3 7.3 1 PMID:21270125 -4.1.2.23 n-acetyl-d-mannosamine escherichia coli 1.1 1.1 1 PMID:21270125 -4.1.2.25 7,8-dihydro-l-monapterin escherichia coli 0.089 0.089 1 PMID:17176045 -4.1.2.25 7,8-dihydro-l-monapterin staphylococcus aureus 0.01 0.01 1 PMID:17176045 -4.1.2.25 7,8-dihydromonapterin mycobacterium tuberculosis 0.006 0.006 1 PMID:23150985 -4.1.2.25 7,8-dihydroneopterin escherichia coli 0.082 0.082 1 PMID:17176045 -4.1.2.25 7,8-dihydroneopterin methanocaldococcus jannaschii 1.0 0.535 2 PMID:24982305 -4.1.2.25 7,8-dihydroneopterin mycobacterium tuberculosis 0.0054 0.0054 1 PMID:23150985 -4.1.2.25 7,8-dihydroneopterin staphylococcus aureus 0.045 0.045 1 PMID:17176045 -4.1.2.26 l-allo-thr pseudomonas putida 1300.0 1300.0 1 PMID:16085854 -4.1.2.26 l-erythro-3-phenylserine pseudomonas putida 7900.0 7900.0 1 PMID:16085854 -4.1.2.26 l-thr pseudomonas putida 580.0 580.0 1 PMID:16085854 -4.1.2.26 l-threo-3-phenylserine pseudomonas putida 2300.0 29.2 3 PMID:16085854;PMID:31152342 -4.1.2.26 l-threo-phenylserine caulobacter vibrioides 67.4 67.4 1 * -4.1.2.27 (2e)-hexadecenal burkholderia pseudomallei 0.22 0.22 1 PMID:27784725 -4.1.2.27 sphinganine 1-phosphate burkholderia pseudomallei 0.015 0.015 1 PMID:27784725 -4.1.2.34 (e)-2'-carboxybenzylidenepyruvate nocardioides sp. 13.0 13.0 1 PMID:9473051 -4.1.2.38 2-hydroxypropiophenone pseudomonas fluorescens 3.4 3.4 1 PMID:17078994 -4.1.2.38 3,5-dimethoxy-benzaldehyde pseudomonas fluorescens 46.15 46.12 3 PMID:18404768 -4.1.2.38 benzaldehyde pseudomonas fluorescens 234.0 234.0 1 PMID:34558792 -4.1.2.38 benzaldehyde rhodococcus erythropolis 15.0 15.0 1 PMID:34558792 -4.1.2.38 benzoin pseudomonas fluorescens 66.9 66.9 1 PMID:17078994 -4.1.2.4 2-deoxy-d-ribose rhodococcus erythropolis 1.23 1.23 1 PMID:22222309 -4.1.2.4 2-deoxy-d-ribose 5-phosphate escherichia coli 521.0 68.0 3 PMID:12467706;PMID:29910900 -4.1.2.4 2-deoxy-d-ribose 5-phosphate halalkalibacterium halodurans 13.3 13.3 1 PMID:31806708 -4.1.2.4 2-deoxy-d-ribose 5-phosphate paenibacillus sp. 320.0 320.0 1 PMID:20622498 -4.1.2.4 2-deoxy-d-ribose 5-phosphate pectobacterium atrosepticum 8.5 8.5 1 * -4.1.2.4 2-deoxy-d-ribose 5-phosphate rhodococcus erythropolis 18.0 18.0 1 PMID:22222309 -4.1.2.4 2-deoxy-d-ribose 5-phosphate thermococcus kodakarensis 116.0 116.0 1 PMID:15205420 -4.1.2.4 2-deoxy-d-ribose 5-phosphate thermus thermophilus 11.4 8.2 2 PMID:15388928 -4.1.2.4 d-2-deoxyribose escherichia coli 0.107 0.107 1 PMID:12467706 -4.1.2.40 d-fructose 1,6-diphosphate streptococcus pyogenes 6.35 5.38 2 PMID:23316044 -4.1.2.40 d-tagatose 1,6-diphosphate streptococcus pyogenes 24.3 19.45 2 PMID:23316044 -4.1.2.42 4-methylsulfonyl benzaldehyde achromobacter xylosoxidans 14.9 14.9 1 PMID:33015743 -4.1.2.42 4-methylsulfonyl benzaldehyde delftia acidovorans 54.01 47.425 2 * -4.1.2.42 alpha-methyl-beta-phenylserine pseudomonas sp. 0.033 0.033 1 PMID:26189018 -4.1.2.42 d-allo-threonine chlamydomonas reinhardtii 25.0 25.0 1 PMID:28038776 -4.1.2.42 d-allo-threonine delftia sp. 0.25 0.25 1 * -4.1.2.42 d-beta-phenylserine pseudomonas sp. 1.4 1.4 1 PMID:26189018 -4.1.2.42 d-threo-phenylserine chlamydomonas reinhardtii 280.0 280.0 1 PMID:28038776 -4.1.2.42 d-threonine chlamydomonas reinhardtii 4.2 4.2 1 PMID:28038776 -4.1.2.42 d-threonine delftia sp. 0.39 0.39 1 * -4.1.2.42 d-threonine pseudomonas sp. 0.4 0.4 1 PMID:26189018 -4.1.2.43 d-ribulose 5-phosphate methylotuvimicrobium alcaliphilum 58.8 58.8 1 PMID:28320301 -4.1.2.43 formaldehyde methylotuvimicrobium alcaliphilum 45.82 45.82 1 PMID:28320301 -4.1.2.43 formaldehyde pyrococcus horikoshii 159.0 110.6 2 PMID:15901685 -4.1.2.44 2,3-dihydro-2,3-dihydroxybenzoyl-coa aromatoleum evansii 20.0 20.0 1 PMID:15916608 -4.1.2.45 trans-o-hydroxybenzylidenepyruvate rhodococcus opacus 0.244 0.244 1 PMID:31161894 -4.1.2.46 acetone cyanohydrin linum usitatissimum 70.0 70.0 1 PMID:35101448 -4.1.2.47 (s)-mandelonitrile hevea brasiliensis 1.83 1.83 1 PMID:20797615 -4.1.2.47 (s)-mandelonitrile manihot esculenta 34.5 28.085 2 PMID:20797615;PMID:21729945 -4.1.2.47 1-naphthalene carboxaldehyde baliospermum montanum 6.0 6.0 1 PMID:25220808 -4.1.2.47 1-naphthalene carboxaldehyde manihot esculenta 23.5 23.5 1 PMID:25220808 -4.1.2.47 2,4-dimethylbenzaldehyde baliospermum montanum 18.5 18.5 1 PMID:21352863 -4.1.2.47 2-methylbenzaldehyde baliospermum montanum 53.6 53.6 1 PMID:21352863 -4.1.2.47 2-nitro-1-phenylethanol hevea brasiliensis 0.15 0.15 1 PMID:25044660 -4.1.2.47 2-thiophene carboxaldehyde baliospermum montanum 31.5 31.5 1 PMID:25220808 -4.1.2.47 2-thiophene carboxaldehyde manihot esculenta 100.0 100.0 1 PMID:25220808 -4.1.2.47 3-methoxybenzaldehyde baliospermum montanum 28.1 28.1 1 PMID:21352863 -4.1.2.47 3-methylbenzaldehyde baliospermum montanum 49.2 49.2 1 PMID:21352863 -4.1.2.47 4-biphenyl carboxaldehyde manihot esculenta 9.2 9.2 1 PMID:25220808 -4.1.2.47 benzaldehyde baliospermum montanum 26.6 26.6 1 PMID:21352863 -4.1.2.47 benzaldehyde manihot esculenta 96.6 96.6 1 PMID:21729945 -4.1.2.47 mandelonitrile hevea brasiliensis 25.0 25.0 1 PMID:25044660 -4.1.2.47 piperonal baliospermum montanum 91.4 91.4 1 PMID:21352863 -4.1.2.47 rac-2-nitro-1-phenylethanol hevea brasiliensis 0.15 0.15 1 PMID:25044660 -4.1.2.47 rac-mandelonitrile hevea brasiliensis 25.0 25.0 1 PMID:25044660 -4.1.2.48 4-methylsulfonylbenzaldehyde pseudomonas putida 7.1 7.1 1 PMID:36793440 -4.1.2.48 alpha-methyl-beta-phenylserine aeromonas veronii 0.54 0.54 1 PMID:26189018 -4.1.2.48 d-beta-phenylserine aeromonas veronii 18.3 18.3 1 PMID:26189018 -4.1.2.48 d-threonine aeromonas veronii 0.2 0.2 1 PMID:26189018 -4.1.2.48 l-4-hydroxythreonine escherichia coli 1.44 1.44 1 PMID:21119630 -4.1.2.48 l-allo-threonine aphanothece halophytica 1.88 1.88 1 PMID:32417544 -4.1.2.48 l-allo-threonine caulobacter vibrioides 20.0 20.0 1 * -4.1.2.48 l-allo-threonine escherichia coli 3.55 3.2 3 PMID:21119630;PMID:24165453;PMID:32417544 -4.1.2.48 l-allo-threonine saccharomyces cerevisiae 41.0 41.0 1 PMID:9151955 -4.1.2.48 l-erythro-phenylserine aphanothece halophytica 95.0 95.0 1 PMID:32417544 -4.1.2.48 l-erythro-phenylserine escherichia coli 52.37 52.37 1 PMID:32417544 -4.1.2.48 l-phenylserine glycine max 1.3 1.3 1 PMID:32014996 -4.1.2.48 l-phenylserine streptomyces coelicolor 0.000107 0.000107 1 PMID:18051291 -4.1.2.48 l-thr streptomyces coelicolor 0.0195 0.0195 1 PMID:18051291 -4.1.2.48 l-threo-3,4-dihydroxyphenylserine streptomyces coelicolor 0.00022 0.00022 1 PMID:18051291 -4.1.2.48 l-threo-phenylserine aphanothece halophytica 6.77 6.77 1 PMID:32417544 -4.1.2.48 l-threo-phenylserine escherichia coli 2.43 2.43 1 PMID:32417544 -4.1.2.48 l-threonine aphanothece halophytica 0.057 0.057 1 PMID:32417544 -4.1.2.48 l-threonine caulobacter vibrioides 3.3 3.3 1 * -4.1.2.48 l-threonine escherichia coli 1.87 1.1 3 PMID:21119630;PMID:24165453;PMID:32417544 -4.1.2.48 l-threonine saccharomyces cerevisiae 43.0 43.0 1 PMID:9151955 -4.1.2.48 l-threonine thermoplasma acidophilum 0.165 0.14100000000000001 2 PMID:34196829 -4.1.2.49 l-allo-threonine aeromonas jandaei 13.8 8.67 3 PMID:24914980;PMID:29928580;PMID:9171400 -4.1.2.49 l-beta-phenylserine aeromonas jandaei 60.5 60.5 1 PMID:29928580 -4.1.2.49 l-threonine aeromonas jandaei 0.641 0.641 1 PMID:24914980 -4.1.2.51 2-dehydro-3-deoxy-d-gluconate picrophilus oshimae 26.7 25.45 2 PMID:20023024 -4.1.2.51 2-dehydro-3-deoxy-d-gluconate 6-phosphate picrophilus oshimae 0.36 0.35 2 PMID:20023024 -4.1.2.52 (s)-4-hydroxy-2-oxopentanoate escherichia coli 353.5 353.5 1 PMID:22908224 -4.1.2.52 2-oxo-3-methyl-4-hydroxypentanoate escherichia coli 14.0 14.0 1 PMID:22908224 -4.1.2.52 3-deoxy-d-manno-oct-2-ulosonic acid escherichia coli 0.55 0.55 1 PMID:15996099 -4.1.2.52 4-hydroxy-2-oxoheptane-1,7-dioate escherichia coli 361.5 361.5 1 PMID:22908224 -4.1.2.52 4-hydroxy-2-oxohexanoate escherichia coli 229.0 229.0 1 PMID:15996099 -4.1.2.52 4-hydroxy-2-oxopentanoate escherichia coli 353.0 353.0 1 PMID:15996099 -4.1.2.52 4-hydroxy-2-oxopentanoic acid escherichia coli 350.0 350.0 1 PMID:18775708 -4.1.2.52 acetaldehyde escherichia coli 205.4 113.65 2 PMID:20364820 -4.1.2.52 butyraldehyde escherichia coli 132.5 132.5 1 PMID:20364820 -4.1.2.52 dl-glyceraldehyde escherichia coli 5.6 5.6 1 PMID:20364820 -4.1.2.52 glycolaldehyde escherichia coli 175.5 175.5 1 PMID:20364820 -4.1.2.52 isobutyraldehyde escherichia coli 64.9 64.9 1 PMID:20364820 -4.1.2.52 propionaldehyde escherichia coli 358.4 358.4 1 PMID:20364820 -4.1.2.52 pyruvate escherichia coli 219.5 219.5 1 PMID:20364820 -4.1.2.52 succinic semialdehyde escherichia coli 203.8 203.8 1 PMID:20364820 -4.1.2.53 2-dehydro-3-deoxy-l-lyxonate escherichia coli 0.3 0.3 2 PMID:18754683;PMID:18754693 -4.1.2.53 2-dehydro-3-deoxy-l-rhamnonate azotobacter vinelandii 54.7 54.7 1 PMID:18505728 -4.1.2.53 2-dehydro-3-deoxy-l-rhamnonate escherichia coli 0.4 0.35 4 PMID:18754683;PMID:18754693 -4.1.2.53 2-dehydro-3-deoxy-l-rhamnonate scheffersomyces stipitis 49.3 49.3 1 PMID:18505728 -4.1.2.53 4-hydroxy-2-oxoheptane-1,7-dioate escherichia coli 299.0 149.77 2 PMID:18754683 -4.1.2.53 4-hydroxy-2-oxohexanoate escherichia coli 447.0 447.0 1 PMID:18754683 -4.1.2.53 4-hydroxy-2-oxopentanoate escherichia coli 396.0 396.0 1 PMID:18754683 -4.1.2.55 2-dehydro-3-deoxy-d-galactonate saccharolobus solfataricus 6.8 6.8 3 PMID:12824170;PMID:16330030;PMID:23315785 -4.1.2.55 2-dehydro-3-deoxy-d-galactonate 6-phosphate saccharolobus solfataricus 34.8 34.8 1 PMID:16330030 -4.1.2.55 2-dehydro-3-deoxy-d-gluconate saccharolobus solfataricus 28.2 28.2 3 PMID:12824170;PMID:16330030;PMID:23315785 -4.1.2.55 2-dehydro-3-deoxy-d-gluconate 6-phosphate saccharolobus solfataricus 61.9 61.9 1 PMID:16330030 -4.1.2.55 2-dehydro-3-deoxy-d-xylonate saccharolobus solfataricus 15.0 15.0 1 PMID:23315785 -4.1.2.55 2-dehydro-3-deoxy-l-arabinonate saccharolobus solfataricus 9.3 9.3 1 PMID:23315785 -4.1.2.55 d-glyceraldehyde saccharolobus solfataricus 9.9 7.7 2 PMID:15614394;PMID:20684556 -4.1.2.55 d-glyceraldehyde sulfolobus acidocaldarius 4.4 4.4 1 PMID:19478916 -4.1.2.55 d-glyceraldehyde acetonide saccharolobus solfataricus 5.4 3.0500000000000003 2 PMID:15614394 -4.1.2.55 l-glyceraldehyde saccharolobus solfataricus 9.9 9.9 1 PMID:15614394 -4.1.2.55 pyruvate saccharolobus solfataricus 4.6 4.6 1 PMID:20684556 -4.1.2.55 pyruvate sulfolobus acidocaldarius 5.5 5.5 1 PMID:19478916 -4.1.2.56 glycerone phosphate streptomyces griseus 0.2 0.2 1 PMID:17003031 -4.1.2.56 l-aspartate 4-semialdehyde streptomyces griseus 0.2 0.2 1 PMID:17003031 -4.1.2.57 6-deoxy-6-sulfo-d-fructose 1-phosphate salmonella enterica subsp. enterica serovar typhimurium 47.7 47.7 1 PMID:33791429 -4.1.2.61 4-coumaroyl-coa pseudomonas fluorescens 2.3 2.3 1 PMID:10222033 -4.1.2.61 feruloyl-coa pseudomonas fluorescens 3.72 3.72 1 PMID:18479250 -4.1.2.62 5-deoxy-d-ribulose 1-phosphate bacillus thuringiensis serovar kurstaki 6.3 6.3 1 PMID:30082730 -4.1.2.62 5-deoxy-d-ribulose 1-phosphate escherichia coli 22.0 22.0 1 PMID:31950558 -4.1.2.62 5-deoxy-d-ribulose 1-phosphate rhodospirillum rubrum 1.94 1.94 1 PMID:31950558 -4.1.2.62 ribulose 1-phosphate escherichia coli 8.7 8.7 1 PMID:31950558 -4.1.2.62 ribulose 1-phosphate rhodospirillum rubrum 0.44 0.44 1 PMID:31950558 -4.1.2.62 s-methyl-5-thio-d-ribulose 1-phosphate escherichia coli 22.0 22.0 1 PMID:31950558 -4.1.2.62 s-methyl-5-thio-d-ribulose 1-phosphate rhodospirillum rubrum 0.94 0.94 1 PMID:31950558 -4.1.2.63 2-hydroxyisobutyryl-coa actinomycetospora chiangmaiensis 1.3 1.3 1 PMID:34952003 -4.1.2.63 acetone rhodospirillales bacterium 2.7 2.7 1 PMID:31383974 -4.1.2.63 formaldehyde homo sapiens 3.8 3.8 1 PMID:31383974 -4.1.2.63 formaldehyde listeria monocytogenes 1.0 1.0 1 PMID:31383974 -4.1.2.63 formaldehyde rhodospirillales bacterium 3.3 3.3 1 PMID:31383974 -4.1.2.63 formyl-coa rhodospirillales bacterium 1.5 1.5 1 PMID:31383974 -4.1.2.63 pentanal rhodospirillales bacterium 2.0 2.0 1 PMID:31383974 -4.1.2.63 propanal rhodospirillales bacterium 4.7 4.7 1 PMID:31383974 -4.1.2.64 2-dehydro-3-deoxy-d-fuconate campylobacter jejuni subsp. jejuni 0.2 0.2 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-d-fuconate veillonella ratti 0.073 0.073 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-d-galactonate campylobacter jejuni subsp. jejuni 0.05 0.05 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-d-galactonate veillonella ratti 0.1035 0.1035 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-d-gluconate campylobacter jejuni subsp. jejuni 1.4 1.4 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-d-gluconate veillonella ratti 1.78 1.78 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-d-pentanoate campylobacter jejuni subsp. jejuni 13.87 13.87 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-d-pentanoate veillonella ratti 44.83 44.83 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-l-fuconate campylobacter jejuni subsp. jejuni 12.45 12.45 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-l-fuconate veillonella ratti 35.83 35.83 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-l-galactonate campylobacter jejuni subsp. jejuni 2.67 2.67 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-l-galactonate veillonella ratti 3.47 3.47 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-l-gluconate campylobacter jejuni subsp. jejuni 0.62 0.62 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-l-gluconate veillonella ratti 0.29 0.29 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-l-pentanoate campylobacter jejuni subsp. jejuni 1.56 1.56 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-l-pentanoate veillonella ratti 22.33 22.33 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-l-rhamnonate campylobacter jejuni subsp. jejuni 2.87 2.87 1 PMID:31914410 -4.1.2.64 2-dehydro-3-deoxy-l-rhamnonate veillonella ratti 4.82 4.82 1 PMID:31914410 -4.1.2.8 (1s,2r)-1-c-(indol-3-yl)glycerol 3-phosphate oryza sativa 6.55 6.55 1 PMID:22000657 -4.1.2.8 (1s,2r)-1-c-(indol-3-yl)glycerol 3-phosphate zea mays 0.006 0.006 1 PMID:18430213 -4.1.2.8 indole-3-glycerol phosphate zea mays 2.3 2.3 1 PMID:11106389 -4.1.2.9 d-fructose 6-phosphate bifidobacterium adolescentis 10.5 6.115 2 PMID:30347514;PMID:31399771 -4.1.2.9 d-fructose 6-phosphate lactococcus lactis subsp. lactis 117.8 117.8 1 PMID:24740691 -4.1.2.9 d-fructose 6-phosphate leuconostoc mesenteroides subsp. mesenteroides 44.2 44.2 1 PMID:24740691 -4.1.2.9 d-fructose 6-phosphate pseudomonas aeruginosa 13.1 13.1 1 PMID:24740691 -4.1.2.9 d-sedoheptulose 7-phosphate bifidobacterium adolescentis 3.5 3.5 1 PMID:30347514 -4.1.2.9 d-xylulose 5-phosphate bifidobacterium adolescentis 17.8 17.8 1 PMID:30347514 -4.1.2.9 d-xylulose 5-phosphate lactococcus lactis subsp. lactis 587.8 587.8 1 PMID:24740691 -4.1.2.9 d-xylulose 5-phosphate leuconostoc mesenteroides subsp. mesenteroides 431.8 431.8 1 PMID:24740691 -4.1.2.9 d-xylulose 5-phosphate pseudomonas aeruginosa 13.2 13.2 1 PMID:24740691 -4.1.3.1 (2r,3s:2s,3r)-2-methyl-isocitrate mycobacterium tuberculosis 1.25 1.25 1 PMID:16879647 -4.1.3.1 dl-isocitrate colwellia maris 18.1 18.1 1 PMID:11440123 -4.1.3.1 dl-isocitrate fomitopsis palustris 32.0 32.0 1 PMID:11888209 -4.1.3.1 glyoxylate mycobacterium tuberculosis 3.6 3.6 1 PMID:24261638 -4.1.3.1 isocitrate aspergillus fumigatus 8.43 8.43 1 PMID:16603391 -4.1.3.1 isocitrate colwellia psychrerythraea 28.5 28.5 1 PMID:17965824 -4.1.3.1 isocitrate geobacillus stearothermophilus 24.0 24.0 1 PMID:236948 -4.1.3.1 isocitrate mycobacterium tuberculosis 12.2 5.220000000000001 4 PMID:16879647;PMID:24261638;PMID:24354272 -4.1.3.1 isocitrate pinus pinea 44.5 44.5 1 PMID:3947071 -4.1.3.1 isocitrate pseudomonas aeruginosa 9.81 9.81 1 PMID:23338961 -4.1.3.1 isocitrate pyricularia oryzae 17.6 17.6 1 PMID:27016285 -4.1.3.1 isocitrate turbatrix aceti 800.0 800.0 1 PMID:4209165 -4.1.3.1 isocitrate vogesella indigofera 122.0 122.0 1 PMID:14285253 -4.1.3.1 succinate mycobacterium tuberculosis 8.5 6.05 2 PMID:24261638;PMID:24354272 -4.1.3.1 threo-dl-isocitrate mycobacterium tuberculosis 9.78 9.78 1 PMID:25576828 -4.1.3.1 threo-ds-isocitrate bacillus sp. (in: firmicutes) 24.0 24.0 1 PMID:687365 -4.1.3.16 4-hydroxy-2-oxoglutarate homo sapiens 6.1 3.5549999999999997 2 PMID:21998747;PMID:31696211 -4.1.3.16 dl-2-keto-4-hydroxyglutarate bos taurus 13.5 13.5 1 PMID:5168885 -4.1.3.17 2-hydroxy-4-oxopentanedioic acid pseudomonas putida 0.25 0.154 2 PMID:20843800 -4.1.3.17 4-carboxy-4-hydroxy-2-oxoadipate pseudomonas putida 145.0 79.2 2 PMID:27741265 -4.1.3.17 4-hydroxy-2-oxopentanoate pseudomonas putida 0.19 0.119 2 PMID:20843800 -4.1.3.17 4-hydroxy-4-methyl-2-oxoglutarate pseudomonas putida 134.0 15.6 5 PMID:20843800;PMID:24359411;PMID:27741265 -4.1.3.17 4-hydroxy-4-methyl-2-oxoglutarate saccharomyces cerevisiae 0.0276 0.0276 1 PMID:24359411 -4.1.3.17 4-hydroxy-4-methyl-2-oxoglutarate thermus thermophilus 0.356 0.356 1 PMID:24359411 -4.1.3.17 oxaloacetate pseudomonas putida 3.16 1.855 4 PMID:20843800;PMID:27741265 -4.1.3.24 (3s)-3-carboxy-3-hydroxypropanoyl-coa chloroflexus aurantiacus 8.8 8.8 1 PMID:12374834 -4.1.3.24 (3s)-malyl-coa cereibacter sphaeroides 2.5 2.5 1 PMID:20047909 -4.1.3.24 acetyl-coa cereibacter sphaeroides 8.6 8.6 1 PMID:20047909 -4.1.3.24 beta-methylmalyl-coa cereibacter sphaeroides 2.8 2.8 1 PMID:20047909 -4.1.3.24 propionyl-coa cereibacter sphaeroides 12.0 12.0 1 PMID:20047909 -4.1.3.27 chorismate [bacillus] caldotenax 383.0 383.0 1 PMID:1478932 -4.1.3.27 chorismate archaeoglobus fulgidus 0.25 0.25 1 PMID:15235940 -4.1.3.27 chorismate mycobacterium tuberculosis 0.26 0.26 1 PMID:26527146 -4.1.3.27 chorismate oryza sativa 0.58 0.2265 10 PMID:15159631;PMID:16040654 -4.1.3.27 chorismate salmonella enterica subsp. enterica serovar typhimurium 4.3 4.3 1 PMID:35816663 -4.1.3.27 chorismate serratia marcescens 5.6 5.6 1 PMID:20532401 -4.1.3.27 chorismate streptomyces venezuelae 0.57 0.57 1 PMID:25355158 -4.1.3.27 l-gln archaeoglobus fulgidus 0.25 0.25 1 PMID:15235940 -4.1.3.27 l-glutamine salmonella enterica subsp. enterica serovar typhimurium 138.0 138.0 1 PMID:20170126 -4.1.3.27 l-glutamine streptomyces venezuelae 0.57 0.57 1 PMID:25355158 -4.1.3.3 (2r,3r,4r)-6-[(aminooxy)carbonyl]-3,4,6-trihydroxy-n-propyltetrahydro-2h-pyran-2-carboxamide haemophilus influenzae 1.23 1.23 1 PMID:15742315 -4.1.3.3 (2s,4s,5r,6r)-5-(acetylamino)-6-[(dipropylamino)carbonyl]-2,4-dihydroxytetrahydro-pyran-2-carboxylic acid escherichia coli 1.22 1.22 1 PMID:15897188 -4.1.3.3 (5r,6r)-7-(dipropylamino)-4,5,6-trihydroxy-2,7-dioxoheptanoic acid escherichia coli 1.22 1.22 1 PMID:20826162 -4.1.3.3 d-3-deoxy-manno-2-octulosonic acid escherichia coli 1.2 1.2 1 PMID:15967977 -4.1.3.3 l-3-deoxy-manno-2-octulosonic acid escherichia coli 1.1 1.1 1 PMID:15967977 -4.1.3.3 n-acetyl-d-mannosamine corynebacterium glutamicum 40.67 23.17 2 PMID:25799411 -4.1.3.3 n-acetyl-d-mannosamine escherichia coli k-12 9.0 9.0 1 PMID:18521592 -4.1.3.3 n-acetyl-d-mannosamine latilactobacillus sakei 4.6 4.6 1 PMID:24817128 -4.1.3.3 n-acetyl-d-mannosamine limosilactobacillus antri 5.4 5.4 1 PMID:24817128 -4.1.3.3 n-acetyl-d-mannosamine pasteurella multocida 11.0 11.0 1 PMID:18521592 -4.1.3.3 n-acetyl-d-mannosamine staphylococcus carnosus 4.5 4.5 1 PMID:22803763 -4.1.3.3 n-acetyl-d-neuraminic acid aliivibrio salmonicida 5.12 5.12 1 PMID:31185017 -4.1.3.3 n-acetyl-d-neuraminic acid escherichia coli 10.5 10.3 3 PMID:15897188;PMID:15967977 -4.1.3.3 n-acetyl-l-neuraminic acid escherichia coli 0.0002 0.0002 1 PMID:15967977 -4.1.3.3 n-acetylneuraminate corynebacterium glutamicum 44.2 26.75 2 PMID:25799411 -4.1.3.3 n-acetylneuraminate escherichia coli 6.75 6.75 1 PMID:19646958 -4.1.3.3 n-acetylneuraminate escherichia coli k-12 10.0 10.0 1 PMID:18521592 -4.1.3.3 n-acetylneuraminate haemophilus influenzae 4.17 4.17 1 PMID:24521460 -4.1.3.3 n-acetylneuraminate latilactobacillus sakei 0.9 0.9 1 PMID:24817128 -4.1.3.3 n-acetylneuraminate limosilactobacillus antri 1.9 1.9 1 PMID:24817128 -4.1.3.3 n-acetylneuraminate pasteurella multocida 16.0 16.0 1 PMID:18521592 -4.1.3.3 n-acetylneuraminate staphylococcus aureus 22.1 0.04 3 PMID:23418011;PMID:27943302 -4.1.3.3 n-acetylneuraminate staphylococcus carnosus 4.0 4.0 1 PMID:22803763 -4.1.3.3 n-acetylneuraminic acid clostridium perfringens 16.7 16.7 1 PMID:182637 -4.1.3.3 n-acetylneuraminic acid escherichia coli 7.7 6.015000000000001 2 PMID:12711733;PMID:20826162 -4.1.3.3 pyruvate corynebacterium glutamicum 42.58 24.34 2 PMID:25799411 -4.1.3.3 pyruvate escherichia coli k-12 1.8 1.8 1 PMID:18521592 -4.1.3.3 pyruvate latilactobacillus sakei 3.9 3.9 1 PMID:24817128 -4.1.3.3 pyruvate limosilactobacillus antri 5.6 5.6 1 PMID:24817128 -4.1.3.3 pyruvate pasteurella multocida 1.9 1.9 1 PMID:18521592 -4.1.3.3 pyruvate staphylococcus carnosus 2.9 2.9 1 PMID:22803763 -4.1.3.3 sialic acid haemophilus influenzae 4.33 4.33 1 PMID:15742315 -4.1.3.30 (2s,3r)-3-hydroxybutane-1,2,3-tricarboxylate aspergillus nidulans 100.0 56.15 2 PMID:11422389 -4.1.3.30 (2s,3r)-3-hydroxybutane-1,2,3-tricarboxylate escherichia coli 19.0 19.0 1 PMID:15723538 -4.1.3.30 (2s,3r)-3-hydroxybutane-1,2,3-tricarboxylate salmonella enterica 105.0 105.0 1 PMID:12897003 -4.1.3.30 mg2+ salmonella enterica 38.0 38.0 1 PMID:12897003 -4.1.3.32 (2r)-ethyl-(3s)-methylmalate aspergillus niger 63.0 63.0 2 PMID:19133276 -4.1.3.32 (2r)-ethylmalate aspergillus niger 4.4 4.4 2 PMID:19133276 -4.1.3.32 (2r)-methylmalate aspergillus niger 2.64 2.64 3 PMID:19133276;PMID:27343740 -4.1.3.32 (2r)-propyl-(3s)-methylmalate aspergillus niger 0.79 0.79 2 PMID:19133276 -4.1.3.32 (2r,3s)-2,3-dimethylmalate aspergillus niger 19.2 19.2 1 PMID:27343740 -4.1.3.32 (2r,3s)-2-methylisocitrate aspergillus niger 0.13 0.13 2 PMID:19133276 -4.1.3.32 (2r,3s)-dimethylmalate aspergillus niger 19.2 19.2 3 PMID:19133276 -4.1.3.32 (2r,3s)-isocitrate aspergillus niger 1e-05 1e-05 1 PMID:19133276 -4.1.3.32 (2r,3s)-methylisocitrate aspergillus niger 0.13 0.13 1 PMID:19133276 -4.1.3.32 (2s)-methylmalate aspergillus niger 1e-05 1e-05 1 PMID:19133276 -4.1.3.32 (2s,3r)-2-methylisocitrate aspergillus niger 0.13 0.13 2 PMID:19133276 -4.1.3.32 (3s)-isopropylmalate aspergillus niger 1e-05 1e-05 1 PMID:19133276 -4.1.3.32 (r)-malate aspergillus niger 1e-05 1e-05 1 PMID:19133276 -4.1.3.32 (s)-malate aspergillus niger 1e-05 1e-05 2 PMID:19133276;PMID:27343740 -4.1.3.32 3,3-difluorooxaloacetate aspergillus niger 1e-05 1e-05 1 PMID:27343740 -4.1.3.32 3,3-difluoroxaloacetate aspergillus niger 1e-05 1e-05 1 PMID:19133276 -4.1.3.32 3-butylmalate aspergillus niger 1e-05 1e-05 1 PMID:19133276 -4.1.3.32 carboxyphosphoenolpyruvate aspergillus niger 1e-05 1e-05 1 PMID:19133276 -4.1.3.32 oxaloacetate aspergillus niger 0.505 0.48 5 PMID:19133276;PMID:27343740 -4.1.3.32 phosphonopyruvate aspergillus niger 1e-05 1e-05 1 PMID:19133276 -4.1.3.34 citryl-coa hydrogenobacter thermophilus 570.0 570.0 1 PMID:15101982 -4.1.3.36 2-(3-carboxypropyl)-benzoyl-coa mycobacterium tuberculosis 0.00025 0.00025 1 PMID:21830810 -4.1.3.36 2-succinylbenzoyl-coa mycobacterium tuberculosis 0.462 0.462 1 PMID:21830810 -4.1.3.36 o-succinylbenzoate escherichia coli 0.021 0.021 1 PMID:23658663 -4.1.3.36 o-succinylbenzoyl-coa escherichia coli 0.062 0.062 1 PMID:21830810 -4.1.3.38 4-amino-4-deoxychorismate mycobacterium tuberculosis 1.9 1.9 1 PMID:33950161 -4.1.3.39 (4s)-4-hydroxy-2-oxopentanoate paraburkholderia xenovorans 4.07 4.07 1 PMID:21425833 -4.1.3.39 (r,s)-glyceraldehyde escherichia coli 5.6 5.6 1 PMID:20364820 -4.1.3.39 (s)-4-hydroxy-2-oxohexanoate mycobacterium tuberculosis 0.38 0.38 1 PMID:23614353 -4.1.3.39 (s)-4-hydroxy-2-oxopentanoate mycobacterium tuberculosis 0.41 0.41 1 PMID:23614353 -4.1.3.39 (s)-4-hydroxy-2-oxopentanoate paraburkholderia xenovorans 4.07 2.43 2 PMID:22574886 -4.1.3.39 acetaldehyde escherichia coli 205.4 205.4 1 PMID:20364820 -4.1.3.39 acetaldehyde paraburkholderia xenovorans 0.86 0.86 2 PMID:20364820;PMID:21425833 -4.1.3.39 acetaldehyde paraburkholderia xenovorans lb400 0.86 0.86 1 PMID:20364820 -4.1.3.39 butyraldehyde escherichia coli 132.5 132.5 1 PMID:20364820 -4.1.3.39 glycolaldehyde escherichia coli 175.5 175.5 1 PMID:20364820 -4.1.3.39 glycolaldehyde paraburkholderia xenovorans 0.4 0.4 1 PMID:20364820 -4.1.3.39 glycolaldehyde paraburkholderia xenovorans lb400 0.4 0.4 1 PMID:20364820 -4.1.3.39 propionaldehyde escherichia coli 358.4 358.4 1 PMID:20364820 -4.1.3.39 propionaldehyde paraburkholderia xenovorans 1.79 1.79 2 PMID:20364820;PMID:21425833 -4.1.3.39 propionaldehyde paraburkholderia xenovorans lb400 1.79 1.79 1 PMID:20364820 -4.1.3.39 pyruvate paraburkholderia xenovorans 1.2 1.2 1 PMID:21425833 -4.1.3.39 succinic semialdehyde escherichia coli 64.9 64.9 1 PMID:20364820 -4.1.3.4 (s)-3-hydroxy-3-methylglutaryl-coa anas sp. 158.0 158.0 1 PMID:6159358 -4.1.3.4 (s)-3-hydroxy-3-methylglutaryl-coa homo sapiens 0.127 0.11599999999999999 2 PMID:8670134 -4.1.3.40 chorismate escherichia coli 1.7 1.5 3 PMID:11825618;PMID:1644758 -4.1.3.40 chorismate mycobacterium tuberculosis 0.215 0.1585 2 PMID:16210318 -4.1.3.40 chorismate stenotrophomonas maltophilia 0.143 0.143 1 PMID:30706936 -4.1.3.40 chorismate stenotrophomonas panacihumi 0.433 0.433 1 PMID:30706936 -4.1.3.40 chorismate xylella fastidiosa 0.65 0.65 1 PMID:30706936 -4.1.3.43 (4r)-4-hydroxy-2-oxopentanoate paraburkholderia xenovorans 0.17 0.1145 4 PMID:21425833;PMID:22081904 -4.1.3.43 (4s)-4-hydroxy-2-oxopentanoate paraburkholderia xenovorans 4.07 0.15150000000000002 6 PMID:21425833;PMID:22081904 -4.1.3.43 4-hydroxy-2-oxoheptanoate paraburkholderia xenovorans 0.63 0.63 1 PMID:19476337 -4.1.3.43 4-hydroxy-2-oxohexanoate paraburkholderia xenovorans 3.9 3.8499999999999996 2 PMID:19476337;PMID:21838275 -4.1.3.43 4-hydroxy-2-oxohexanoate thermus thermophilus 3.9 2.1 5 PMID:22316175 -4.1.3.43 4-hydroxy-2-oxopentanoate paraburkholderia xenovorans 4.1 4.07 3 PMID:19476337;PMID:21838275 -4.1.3.43 4-hydroxy-2-oxopentanoate thermus thermophilus 4.1 0.895 10 PMID:22316175 -4.1.3.43 acetaldehyde paraburkholderia xenovorans 0.94 0.86 7 PMID:20364820;PMID:21425833;PMID:22081904 -4.1.3.43 butyraldehyde paraburkholderia xenovorans 0.64 0.28 4 PMID:21425833;PMID:22081904 -4.1.3.43 glycolaldehyde paraburkholderia xenovorans 0.4 0.4 1 PMID:20364820 -4.1.3.43 oxaloacetate paraburkholderia xenovorans 16.5 0.335 6 PMID:19476337;PMID:22081904 -4.1.3.43 pentaldehyde paraburkholderia xenovorans 0.58 0.14 3 PMID:21425833;PMID:22081904 -4.1.3.43 propionaldehyde paraburkholderia xenovorans 1.79 0.45999999999999996 8 PMID:20364820;PMID:21425833;PMID:22081904 -4.1.3.43 pyruvate paraburkholderia xenovorans 1.2 0.32 7 PMID:20364820;PMID:21425833;PMID:22081904 -4.1.3.45 3-hydroxybenzoate streptomyces sp. 0.11 0.11 1 PMID:23824670 -4.1.3.45 chorismate lentzea aerocolonigenes 0.633 0.633 1 PMID:30706936 -4.1.3.45 chorismate streptomyces conglobatus 0.176 0.10850000000000001 4 PMID:32165500 -4.1.3.45 chorismate streptomyces hygroscopicus 22.4 22.4 1 PMID:21383123 -4.1.3.45 chorismate xylella fastidiosa 0.65 0.65 1 PMID:30706936 -4.1.3.46 (3r)-citramalyl-coa chloroflexus aurantiacus 1.7 1.7 1 PMID:17259315 -4.1.99.1 beta-(benzimidazol-1-yl)-l-alanine escherichia coli 5.6 5.6 1 PMID:23438036 -4.1.99.1 beta-chloro-l-ala escherichia coli 12.4 12.4 1 PMID:21081107 -4.1.99.1 beta-chloro-l-ala photobacterium profundum 3.0 3.0 1 PMID:21081107 -4.1.99.1 l-trp porphyromonas gingivalis 1.37 0.805 2 PMID:19246767 -4.1.99.1 l-trp symbiobacterium thermophilum 42.0 42.0 1 PMID:1368766 -4.1.99.1 l-tryptophan escherichia coli 6.8 6.0 3 PMID:21081107;PMID:23438036;PMID:30082510 -4.1.99.1 l-tryptophan photobacterium profundum 2.5 2.5 1 PMID:21081107 -4.1.99.1 l-tryptophan prevotella intermedia 0.45 0.45 1 PMID:21658104 -4.1.99.1 l-tryptophan vibrio cholerae o1 5.252 5.252 1 PMID:25253268 -4.1.99.1 s-(2-nitrophenyl)-l-cysteine escherichia coli 44.0 41.0 2 PMID:21081107;PMID:30082510 -4.1.99.1 s-(2-nitrophenyl)-l-cysteine photobacterium profundum 13.9 13.9 1 PMID:21081107 -4.1.99.1 s-benzyl-l-cys escherichia coli 5.2 5.2 1 PMID:21081107 -4.1.99.1 s-benzyl-l-cys photobacterium profundum 1.1 1.1 1 PMID:21081107 -4.1.99.1 s-benzyl-l-cysteine vibrio cholerae o1 0.346 0.346 1 PMID:25253268 -4.1.99.1 s-ethyl-l-cys escherichia coli 6.0 6.0 1 PMID:21081107 -4.1.99.1 s-ethyl-l-cys photobacterium profundum 0.4 0.4 1 PMID:21081107 -4.1.99.1 s-ethyl-l-cysteine escherichia coli 6.0 6.0 1 PMID:30082510 -4.1.99.1 s-ethyl-l-cysteine porphyromonas gingivalis 1.87 1.87 1 PMID:19246767 -4.1.99.1 s-ethyl-l-cysteine prevotella intermedia 1.79 1.79 1 PMID:21658104 -4.1.99.1 s-methyl-l-cys escherichia coli 5.0 5.0 1 PMID:21081107 -4.1.99.1 s-methyl-l-cys photobacterium profundum 0.2 0.2 1 PMID:21081107 -4.1.99.1 s-methyl-l-cysteine porphyromonas gingivalis 0.5 0.5 1 PMID:19246767 -4.1.99.1 s-methyl-l-cysteine prevotella intermedia 0.2 0.2 1 PMID:21658104 -4.1.99.1 s-methyl-l-cysteine vibrio cholerae o1 0.49 0.49 1 PMID:25253268 -4.1.99.11 toluene thauera aromatica 0.35 0.22999999999999998 2 PMID:17105211 -4.1.99.12 d-ribulose 5-phosphate vibrio cholerae o1 2.2 2.2 1 PMID:35802469 -4.1.99.16 (2e,6e)-farnesyl diphosphate streptomyces avermitilis 0.0031 0.0031 1 PMID:17080683 -4.1.99.2 2-chloro-l-alanine citrobacter freundii 6.0 6.0 1 PMID:29183854 -4.1.99.2 3,4-dihydroxyphenyl-l-alanine citrobacter freundii 0.31 0.31 1 PMID:17094783 -4.1.99.2 3-chloro-l-ala citrobacter freundii 3.0 0.7 3 PMID:16793353;PMID:7547970;PMID:9174368;PMID:9880502 -4.1.99.2 3-chloro-l-ala escherichia coli 3.0 3.0 1 PMID:9174368;PMID:9880502 -4.1.99.2 3-fluoro-l-tyr citrobacter freundii 1.4 1.4 2 PMID:16793353;PMID:7744078 -4.1.99.2 3-fluoro-l-tyrosine citrobacter freundii 1.4 1.4 3 PMID:25758959;PMID:29183854;PMID:35577764 -4.1.99.2 ala citrobacter intermedius 0.00153 0.00153 1 PMID:3691524 -4.1.99.2 beta-chloro-l-alanine citrobacter freundii 6.0 6.0 1 PMID:25758959 -4.1.99.2 d-ala citrobacter freundii 0.01 0.009000000000000001 2 PMID:7744078;PMID:8218227 -4.1.99.2 l-ala citrobacter freundii 0.03 0.03 1 PMID:7744078 -4.1.99.2 l-dopa fusobacterium nucleatum subsp. nucleatum 0.54 0.54 1 PMID:29499786 -4.1.99.2 l-m-tyr citrobacter intermedius 0.00268 0.00268 1 PMID:3691524 -4.1.99.2 l-met citrobacter freundii 0.015 0.015 1 PMID:15560798 -4.1.99.2 l-phe citrobacter freundii 6.08 3.414 2 PMID:15560798 -4.1.99.2 l-ser citrobacter freundii 0.17 0.17 1 PMID:7744078 -4.1.99.2 l-tyr citrobacter freundii 3.5 3.5 3 PMID:16793353;PMID:7547970;PMID:7744078;PMID:9174368 -4.1.99.2 l-tyr escherichia coli 3.7 3.7 1 PMID:9880502 -4.1.99.2 l-tyrosine citrobacter freundii 3.5 3.5 5 PMID:17094783;PMID:25758959;PMID:29183854;PMID:35577764 -4.1.99.2 l-tyrosine fusobacterium nucleatum subsp. nucleatum 1.72 1.72 1 PMID:29499786 -4.1.99.2 l-tyrosine morganella morganii 1.46 1.46 1 PMID:32236865 -4.1.99.2 o-benzoyl-l-ser citrobacter freundii 8.3 8.3 2 PMID:7547970;PMID:9174368 -4.1.99.2 o-benzyl-l-cys citrobacter freundii 3.9 3.9 1 PMID:9174368 -4.1.99.2 phe citrobacter intermedius 0.0008 0.0008 1 PMID:3691524 -4.1.99.2 phenol fusobacterium nucleatum subsp. nucleatum 0.44 0.44 1 PMID:29499786 -4.1.99.2 pyrocatechol fusobacterium nucleatum subsp. nucleatum 2.68 2.68 1 PMID:29499786 -4.1.99.2 s-(2-nitrophenyl)-l-cysteine citrobacter freundii 9.7 9.65 4 PMID:25758959;PMID:29183854;PMID:35577764 -4.1.99.2 s-(o-nitrophenyl)-l-cys citrobacter freundii 9.7 5.1 4 PMID:16793353;PMID:7744078;PMID:9174368 -4.1.99.2 s-benzyl-l-cys citrobacter freundii 0.52 0.5 3 PMID:16793353;PMID:7744078;PMID:9174368 -4.1.99.2 s-benzyl-l-cysteine citrobacter freundii 0.63 0.63 2 PMID:25758959;PMID:29183854 -4.1.99.2 s-ethyl-l-cys citrobacter freundii 3.88 2.79 2 PMID:7744078;PMID:9174368 -4.1.99.2 s-ethyl-l-cysteine citrobacter freundii 5.4 4.65 4 PMID:25758959;PMID:29183854;PMID:35577764 -4.1.99.2 s-methyl-l-cys citrobacter freundii 0.9 0.9 3 PMID:16793353;PMID:7547970;PMID:9174368 -4.1.99.2 s-methyl-l-cysteine citrobacter freundii 1.13 1.13 2 PMID:25758959;PMID:29183854 -4.1.99.2 ser citrobacter intermedius 0.012 0.006500000000000001 2 PMID:3691524 -4.1.99.2 tyr citrobacter intermedius 0.2 0.2 1 PMID:3691524 -4.1.99.20 2-amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoate streptomyces griseus 0.025 0.025 1 PMID:17003031 -4.1.99.22 gtp staphylococcus aureus 0.0007 0.0007 1 PMID:25697423 -4.1.99.22 s-adenosyl-l-methionine staphylococcus aureus 0.00075 0.00075 1 PMID:25697423 -4.1.99.27 (-)-4'-methoxycyclopenine aspergillus nidulans 226.7 226.7 1 PMID:30026518 -4.1.99.27 (-)-cyclopenine aspergillus nidulans 0.267 0.2005 2 PMID:30026518 -4.1.99.28 3'-dehydrocarminate microbacterium sp. 5-2b 23.0 23.0 1 PMID:34728636 -4.1.99.28 3'-dehydrohomoorientin microbacterium sp. 5-2b 0.024 0.024 1 PMID:34728636 -4.1.99.28 3'-dehydromangiferin microbacterium sp. 5-2b 0.16 0.16 1 PMID:34728636 -4.1.99.28 3'-dehydropuerarin microbacterium sp. 5-2b 0.12 0.12 1 PMID:34728636 -4.1.99.3 cyclobutadipyrimidine in dna escherichia coli 0.2167 0.14485 2 PMID:20438097 -4.1.99.3 cyclobutadipyrimidine in dna vibrio cholerae serotype o1 0.23 0.18 2 PMID:20438097 -4.1.99.3 pyrimidine dimer in dna escherichia coli 0.04 0.04 1 PMID:6325459 -4.1.99.5 n-heptanal synechococcus elongatus 0.0073 0.0073 1 PMID:23759169 -4.1.99.5 n-heptanal synechococcus elongatus pcc 7942 = fachb-805 0.013 0.010499999999999999 2 PMID:27588038;PMID:28302170 -4.1.99.5 n-heptanal synechocystis sp. pcc 6803 0.0098 0.0098 1 PMID:28302170 -4.1.99.5 n-hexadecanal synechococcus elongatus pcc 7942 = fachb-805 0.0075 0.0075 1 PMID:28302170 -4.1.99.5 n-hexadecanal synechocystis sp. pcc 6803 0.0073 0.0073 1 PMID:28302170 -4.1.99.5 n-hexanal synechococcus elongatus pcc 7942 = fachb-805 0.03 0.03 1 PMID:27588038 -4.1.99.5 n-nonanal synechococcus elongatus pcc 7942 = fachb-805 0.01 0.01 1 PMID:27588038 -4.1.99.5 n-octanal synechococcus elongatus pcc 7942 = fachb-805 0.023 0.023 1 PMID:27588038 -4.1.99.5 octadecanal nostoc punctiforme 0.0018 0.0018 1 PMID:24313866 -4.1.99.5 trans-3-nonyloxirane-2-carbaldehyde nostoc punctiforme 0.00027 0.00027 1 PMID:24313866 -4.1.99.5 trans-3-pentadecanyloxirane-2-carbaldehyde nostoc punctiforme 0.00048 0.00048 1 PMID:24313866 -4.2.1.1 4-nitrophenyl acetate corynebacterium flavescens 80.56 80.56 1 PMID:35640707 -4.2.1.1 co2 acipenser gueldenstaedtii 1200000.0 1200000.0 1 PMID:21381885 -4.2.1.1 co2 anguilla anguilla 25000.0 25000.0 1 PMID:11807116 -4.2.1.1 co2 arabidopsis thaliana 0.32 0.32 1 PMID:12147257 -4.2.1.1 co2 astrosclera willeyana 900000.0 900000.0 1 PMID:22285172 -4.2.1.1 co2 brucella suis 640000.0 352000.0 4 PMID:20158185;PMID:20211561;PMID:21251841 -4.2.1.1 co2 caenorhabditis elegans 685000.0 685000.0 1 PMID:20842438 -4.2.1.1 co2 candida albicans 2010000.0 800000.0 3 PMID:18723348;PMID:20061162 -4.2.1.1 co2 chionodraco hamatus 66700.0 66685.0 2 PMID:11807116 -4.2.1.1 co2 clostridium perfringens 15000.0 15000.0 1 PMID:23475974 -4.2.1.1 co2 columba livia 1300000.0 1300000.0 1 PMID:21476925 -4.2.1.1 co2 colwellia psychrerythraea 600000.0 600000.0 1 PMID:26778292 -4.2.1.1 co2 conticribra weissflogii 130000.0 130000.0 3 PMID:23656892;PMID:24268544;PMID:24456295 -4.2.1.1 co2 cryptococcus neoformans 680000.0 390000.0 3 PMID:18723348;PMID:20061162 -4.2.1.1 co2 cyprinus carpio 26000.0 26000.0 1 PMID:15146348 -4.2.1.1 co2 drosophila melanogaster 950000.0 950000.0 1 PMID:20659325 -4.2.1.1 co2 entamoeba histolytica 670000.0 670000.0 1 PMID:30486513 -4.2.1.1 co2 enterobacter sp. b13 480000.0 480000.0 1 PMID:26497870 -4.2.1.1 co2 escherichia coli 570000.0 570000.0 1 PMID:32746656 -4.2.1.1 co2 felis catus 10000.0 6000.0 2 PMID:3919025 -4.2.1.1 co2 flaveria bidentis 120000.0 120000.0 1 PMID:23414801 -4.2.1.1 co2 gyrodactylus salaris 110000.0 110000.0 1 PMID:35637617 -4.2.1.1 co2 halothiobacillus neapolitanus 89000.0 89000.0 1 PMID:17012396 -4.2.1.1 co2 helicobacter pylori 240000.0 240000.0 1 PMID:11341916 -4.2.1.1 co2 homo sapiens 4200000.0 150000.0 27 PMID:11121027;PMID:18353640;PMID:18618322;PMID:18703501;PMID:19036170;PMID:19679200;PMID:22386980;PMID:23098192;PMID:31481705;PMID:35947329;PMID:6424649;PMID:7758465;PMID:9054574 -4.2.1.1 co2 lacticaseibacillus rhamnosus 986000.0 986000.0 1 PMID:35612631 -4.2.1.1 co2 lathyrus oleraceus 740000.0 310000.0 3 PMID:9882424 -4.2.1.1 co2 leishmania chagasi 935000.0 935000.0 1 PMID:23977960 -4.2.1.1 co2 malassezia globosa 860000.0 860000.0 1 PMID:23391336 -4.2.1.1 co2 malassezia pachydermatis 380000.0 380000.0 1 PMID:34894958 -4.2.1.1 co2 mesorhizobium loti 813600.0 813600.0 1 PMID:19218391 -4.2.1.1 co2 methanosarcina thermophila 71900.0 1075.0 64 PMID:10529183;PMID:10924116;PMID:11781108;PMID:20023030;PMID:23111186 -4.2.1.1 co2 methanothermobacter thermautotrophicus 24000.0 15000.0 4 PMID:10515911;PMID:12107142 -4.2.1.1 co2 micropterus salmoides 49000.0 49000.0 1 PMID:15146348 -4.2.1.1 co2 mus musculus 940000.0 450000.0 7 PMID:18353640;PMID:18501600;PMID:19193158;PMID:9153196;PMID:9692974 -4.2.1.1 co2 mycobacterium tuberculosis 430000.0 410000.0 2 PMID:19317447;PMID:19338333 -4.2.1.1 co2 mytilus galloprovincialis 420000.0 415000.0 2 PMID:28741386 -4.2.1.1 co2 neisseria gonorrhoeae 18300.0 18300.0 1 PMID:9108244 -4.2.1.1 co2 nostoc commune 950000.0 950000.0 1 PMID:25804721 -4.2.1.1 co2 nostoc sp. 20000.0 20000.0 1 PMID:24907906 -4.2.1.1 co2 oncorhynchus mykiss 302800.0 89000.0 3 PMID:15146348;PMID:15879075 -4.2.1.1 co2 oryctolagus cuniculus 9000.0 5170.0 4 PMID:9705205 -4.2.1.1 co2 oryza sativa 110000.0 110000.0 1 PMID:17208453 -4.2.1.1 co2 persephonella marina 320000.0 320000.0 1 * -4.2.1.1 co2 plasmodium falciparum 380000.0 260000.0 2 PMID:27485387 -4.2.1.1 co2 populus tremula 3000.0 2835.0 2 PMID:9247540 -4.2.1.1 co2 porphyromonas gingivalis 410000.0 345000.0 2 PMID:23769640;PMID:25032746 -4.2.1.1 co2 pseudoalteromonas haloplanktis ant/505 140000.0 140000.0 1 PMID:26145820 -4.2.1.1 co2 rattus norvegicus 58300.0 58300.0 1 PMID:6425289 -4.2.1.1 co2 saccharomyces cerevisiae 940000.0 940000.0 2 PMID:18993072;PMID:20819061 -4.2.1.1 co2 sander vitreus 22000.0 22000.0 1 PMID:15146348 -4.2.1.1 co2 sordaria macrospora 13000.0 12500.0 2 PMID:24506675 -4.2.1.1 co2 struthio camelus 1200000.0 1200000.0 1 PMID:16206834 -4.2.1.1 co2 stylophora pistillata 920000.0 490000.0 4 PMID:18617510;PMID:20176489 -4.2.1.1 co2 sulfurihydrogenibium azorense 4400000.0 4400000.0 2 PMID:23294703;PMID:25817590 -4.2.1.1 co2 synechocystis sp. pcc 6803 / kazusa 31000.0 13700.0 3 PMID:27729545 -4.2.1.1 co2 thalassiosira pseudonana 200.0 200.0 1 PMID:23656892 -4.2.1.1 co2 trematomus bernacchii 55000.0 55000.0 1 PMID:11807116 -4.2.1.1 co2 trichomonas vaginalis 490000.0 435000.0 2 PMID:32515610;PMID:34652457 -4.2.1.1 co2 trypanosoma cruzi 1210000.0 1210000.0 1 PMID:23391336 -4.2.1.1 co2 vibrio cholerae serotype o1 823000.0 823000.0 1 PMID:23181552 -4.2.1.1 cos bos taurus 41.0 41.0 1 PMID:15792633 -4.2.1.1 cs2 bos taurus 0.0005 0.0005 1 PMID:15792633 -4.2.1.1 h2co3 danio rerio 890000.0 890000.0 1 PMID:29230365 -4.2.1.1 h2co3 dunaliella salina 45000.0 41200.0 7 PMID:15047915;PMID:15894606 -4.2.1.1 h2co3 homo sapiens 1400000.0 29500.0 3 PMID:15894606;PMID:26184158 -4.2.1.1 h2co3 mesorhizobium loti 121500.0 121500.0 1 PMID:19218391 -4.2.1.1 h2co3 methanosarcina thermophila 243000.0 231000.0 3 PMID:26184158 -4.2.1.1 h2co3 methanothermobacter thermautotrophicus 17000.0 17000.0 1 PMID:26184158 -4.2.1.1 h2co3 persephonella marina 320000.0 320000.0 1 PMID:26184158 -4.2.1.1 h2co3 plasmodium falciparum 380000.0 380000.0 1 PMID:27615265 -4.2.1.1 h2co3 python bivittatus 13000.0 13000.0 1 PMID:26005204 -4.2.1.1 h2co3 salmo trutta labrax coruhensis 688.0 688.0 1 PMID:27175889 -4.2.1.1 h2co3 sulfurihydrogenibium azorense 4400000.0 4400000.0 1 PMID:26184158 -4.2.1.1 h2co3 sulfurihydrogenibium sp. yo3aop1 935000.0 935000.0 1 PMID:26184158 -4.2.1.1 h2co3 thermovibrio ammonificans 1600000.0 1600000.0 1 PMID:26184158 -4.2.1.1 hco3- halothiobacillus neapolitanus 46000.0 46000.0 1 PMID:17012396 -4.2.1.1 hco3- mus musculus 190000.0 190000.0 1 PMID:9692974 -4.2.1.1 histamine nakaseomyces glabratus 1070000.0 725000.0 2 PMID:20129782 -4.2.1.10 (2r)-2-(4-methoxybenzyl)-3-dehydroquinic acid mycobacterium tuberculosis 0.1542 0.1542 1 PMID:24392963 -4.2.1.10 (2r)-2-methyl-3-dehydroquinic acid mycobacterium tuberculosis 0.66 0.66 1 PMID:24957267 -4.2.1.10 3-dehydroquinate acetivibrio clariflavus 59.61 59.61 1 PMID:25852984 -4.2.1.10 3-dehydroquinate alcanivorax borkumensis 13.53 13.53 1 PMID:25852984 -4.2.1.10 3-dehydroquinate alicyclobacillus acidocaldarius 119.98 119.98 1 PMID:25852984 -4.2.1.10 3-dehydroquinate bacillus subtilis 10.46 10.46 1 PMID:25852984 -4.2.1.10 3-dehydroquinate citrobacter koseri 208.96 208.96 1 PMID:25852984 -4.2.1.10 3-dehydroquinate clostridioides difficile 125.0 125.0 1 PMID:21087925 -4.2.1.10 3-dehydroquinate corynebacterium glutamicum 52.26 52.26 1 PMID:25852984 -4.2.1.10 3-dehydroquinate crystallibacter crystallopoietes 184.43 184.43 1 PMID:25852984 -4.2.1.10 3-dehydroquinate enterococcus faecalis 110.0 110.0 1 PMID:25072253 -4.2.1.10 3-dehydroquinate escherichia coli 29.53 29.53 1 PMID:25852984 -4.2.1.10 3-dehydroquinate eshraghiella crossota 42.2 42.2 1 PMID:25852984 -4.2.1.10 3-dehydroquinate eucalyptus camaldulensis 60.4 30.9 3 PMID:33346890 -4.2.1.10 3-dehydroquinate geobacillus sp. y4.1mc1 5.33 5.33 1 PMID:25852984 -4.2.1.10 3-dehydroquinate glaciozyma antarctica 1094.0 1094.0 1 PMID:33539893 -4.2.1.10 3-dehydroquinate gluconobacter oxydans 77.06 77.06 1 PMID:25852984 -4.2.1.10 3-dehydroquinate halanaerobium hydrogeniformans 75.11 75.11 1 PMID:25852984 -4.2.1.10 3-dehydroquinate helicobacter pylori 2.0 0.87 4 PMID:19856378;PMID:21275049;PMID:8912695 -4.2.1.10 3-dehydroquinate klebsiella aerogenes 102.15 102.15 1 PMID:25852984 -4.2.1.10 3-dehydroquinate klebsiella pneumoniae 102.7 102.7 1 PMID:25852984 -4.2.1.10 3-dehydroquinate lancefieldella rimae 9.06 9.06 1 PMID:25852984 -4.2.1.10 3-dehydroquinate micromonospora lupini 4.63 4.63 1 PMID:25852984 -4.2.1.10 3-dehydroquinate mycobacterium tuberculosis 154.0 5.75 6 PMID:12387860;PMID:19856378;PMID:21275049;PMID:24957267;PMID:25852984 -4.2.1.10 3-dehydroquinate natranaerobius thermophilus 3.8 3.8 1 PMID:25852984 -4.2.1.10 3-dehydroquinate pseudomonas aeruginosa 18.72 18.72 1 PMID:25372814 -4.2.1.10 3-dehydroquinate pseudomonas putida 78.87 78.87 1 PMID:25852984 -4.2.1.10 3-dehydroquinate psychrobacter sp. prwf-1 31.7 31.7 1 PMID:25852984 -4.2.1.10 3-dehydroquinate psychromonas ingrahamii 10.59 10.59 1 PMID:25852984 -4.2.1.10 3-dehydroquinate ruminococcus champanellensis 50.2 50.2 1 PMID:25852984 -4.2.1.10 3-dehydroquinate salmonella enterica 310.0 210.0 3 PMID:21087925;PMID:21291284;PMID:23341204 -4.2.1.10 3-dehydroquinate salmonella enterica subsp. enterica serovar typhi 20.0 10.55 2 PMID:1329726;PMID:24957267 -4.2.1.10 3-dehydroquinate streptomyces acidiscabies 211.83 211.83 1 PMID:25852984 -4.2.1.10 3-dehydroquinate streptomyces coelicolor 124.0 84.0 3 PMID:12387860;PMID:21275049 -4.2.1.10 3-dehydroquinate thermodesulfobium narugense 6.88 6.88 1 PMID:25852984 -4.2.1.10 3-dehydroquinate thermomonospora curvata 11.92 11.92 1 PMID:25852984 -4.2.1.10 3-dehydroquinate xylella fastidiosa 7.15 7.15 1 PMID:25852984 -4.2.1.100 cyclohexa-1,5-diene-1-carbonyl-coa geobacter metallireducens 280.0 280.0 1 PMID:17122342 -4.2.1.100 cyclohexa-1,5-diene-1-carbonyl-coa syntrophus aciditrophicus 175.0 175.0 1 PMID:17122342 -4.2.1.100 cyclohexa-1,5-diene-1-carbonyl-coa thauera aromatica 51.0 51.0 1 PMID:9738901 -4.2.1.103 2,3,4,6-tetradeoxy-2,6-bis[3-(methylidyneazaniumyl)butanamido]hexopyranose streptomyces thioluteus 0.024 0.024 1 PMID:29863887 -4.2.1.103 2-naphthyl isocyanide pseudomonas fluorescens 0.216 0.216 1 PMID:20630867 -4.2.1.103 4,4'-[(6-hydroxyhexane-1,5-diyl)bis(azanediyl)]bis(n-methylidyne-4-oxobutan-2-aminium) streptomyces thioluteus 0.0163 0.0163 1 PMID:29863887 -4.2.1.103 cyclohexyl isocyanide streptomyces thioluteus 5.08 5.08 1 PMID:29863887 -4.2.1.104 cyanate thermomyces lanuginosus 35600.0 35600.0 1 PMID:33431973 -4.2.1.105 2,5,7,4'-tetrahydroxyisoflavanone glycine max 18.1 18.1 1 PMID:15734910 -4.2.1.105 2,5,7,4'-tetrahydroxyisoflavanone glycyrrhiza echinata 0.19 0.19 1 PMID:15734910 -4.2.1.105 2,7,4'-trihydroxyisoflavanone glycine max 5.3 5.3 1 PMID:15734910 -4.2.1.105 2,7,4'-trihydroxyisoflavanone glycyrrhiza echinata 0.12 0.12 1 PMID:15734910 -4.2.1.105 2,7-dihydroxy-4'-methoxyisoflavanone glycine max 1.6 1.6 1 PMID:15734910 -4.2.1.105 2,7-dihydroxy-4'-methoxyisoflavanone glycyrrhiza echinata 9.8 9.8 1 PMID:15734910 -4.2.1.106 7alpha-hydroxy-3-oxochol-4-en-24-oate [clostridium] hylemonae 18.6 18.6 1 PMID:26650892 -4.2.1.106 7alpha-hydroxy-3-oxochol-4-en-24-oate [clostridium] scindens 24.0 21.0 2 PMID:26650892 -4.2.1.106 7alpha-hydroxy-3-oxochol-4-en-24-oate peptacetobacter hiranonis 4.4 4.4 1 PMID:26650892 -4.2.1.106 7alpha-hydroxy-3-oxochol-4-en-24-oyl-coa [clostridium] hylemonae 12.6 12.6 1 PMID:26650892 -4.2.1.106 7alpha-hydroxy-3-oxochol-4-en-24-oyl-coa [clostridium] scindens 98.0 56.5 2 PMID:26650892 -4.2.1.106 7alpha-hydroxy-3-oxochol-4-en-24-oyl-coa peptacetobacter hiranonis 22.2 22.2 1 PMID:26650892 -4.2.1.108 (2s)-4-acetamido-2-aminobutanoate sphingopyxis alaskensis 7.2 7.2 1 PMID:26986827 -4.2.1.108 n-alpha-acetyl-l-2,4-diaminobutanoate sphingopyxis alaskensis 0.6 0.6 1 PMID:26986827 -4.2.1.109 s-methyl-5-thio-d-ribulose 1-phosphate bacillus subtilis 16.5 16.5 1 PMID:18391471 -4.2.1.11 2-phospho-d-glycerate homo sapiens 81.68 81.68 1 * -4.2.1.11 2-phospho-d-glycerate klebsiella pneumoniae 52.7 52.7 1 * -4.2.1.11 2-phospho-d-glycerate plasmodium falciparum 22.2 21.4 2 PMID:19268421 -4.2.1.11 2-phospho-d-glycerate saccharomyces cerevisiae 230.0 71.4 5 PMID:23359425;PMID:8634301;PMID:9602170 -4.2.1.11 2-phospho-d-glycerate theileria annulata 37.0 37.0 1 PMID:24664479 -4.2.1.11 phosphoenolpyruvate homo sapiens 34.07 34.07 1 * -4.2.1.11 phosphoenolpyruvate klebsiella pneumoniae 15.47 15.47 1 * -4.2.1.113 (1r,6r)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate amycolatopsis sp. 120.0 120.0 1 PMID:14705949 -4.2.1.113 (1r,6r)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate escherichia coli 80.0 52.0 2 PMID:22775324;PMID:24060347 -4.2.1.113 (1r,6r)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate exiguobacterium sp. 51.0 51.0 1 PMID:24937446 -4.2.1.113 (1r,6r)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate thermobifida fusca 122.0 122.0 1 PMID:24060347 -4.2.1.114 (1e)-hex-1-ene-1,2,6-tricarboxylic acid methanocaldococcus jannaschii 2.5 2.5 1 PMID:20170198 -4.2.1.114 (1e)-pent-1-ene-1,2,5-tricarboxylic acid methanocaldococcus jannaschii 0.66 0.66 1 PMID:20170198 -4.2.1.114 (r)-homocitrate methanocaldococcus jannaschii 0.37 0.37 1 PMID:18765671 -4.2.1.114 but-1-ene-1,2,4-tricarboxylic acid methanocaldococcus jannaschii 0.75 0.75 1 PMID:20170198 -4.2.1.114 cis-homo2aconitate methanocaldococcus jannaschii 0.66 0.66 1 PMID:18765671 -4.2.1.114 cis-homo3aconitate methanocaldococcus jannaschii 2.5 2.5 1 PMID:18765671 -4.2.1.114 cis-homo4aconitate methanocaldococcus jannaschii 5.6 5.6 1 PMID:18765671 -4.2.1.114 cis-homoaconitate methanocaldococcus jannaschii 0.75 0.75 1 PMID:18765671 -4.2.1.114 maleate methanocaldococcus jannaschii 6.0 6.0 1 PMID:18765671 -4.2.1.115 udp-n-acetylglucosamine helicobacter pylori 0.095 0.095 1 PMID:12004063 -4.2.1.116 3-hydroxypropionyl-coa metallosphaera sedula 96.0 96.0 1 PMID:19429610 -4.2.1.118 (-)-3-dehydroshikimate bacillus thuringiensis 3.8 3.8 1 PMID:18975921 -4.2.1.118 3-dehydro-shikimate bacillus thuringiensis 1.1 1.1 1 PMID:35889076 -4.2.1.118 3-dehydro-shikimate corynebacterium glutamicum 60.8 60.8 3 PMID:32822353;PMID:35889076 -4.2.1.118 3-dehydro-shikimate neurospora crassa 218.6 218.6 1 PMID:35889076 -4.2.1.118 3-dehydro-shikimate penicillium parvum 5.6 5.6 1 PMID:35612974 -4.2.1.118 3-dehydro-shikimate pseudomonas putida 163.6 163.6 3 PMID:27706847;PMID:32822353 -4.2.1.119 (2e)-2-decenoyl-coa candida tropicalis 388.0 388.0 1 PMID:12832794 -4.2.1.119 (2e)-2-decenoyl-coa homo sapiens 196.0 150.5 2 PMID:10671535 -4.2.1.119 (2e)-butenoyl-coa drosophila melanogaster 0.38 0.38 1 PMID:21320074 -4.2.1.119 (2e)-decenoyl-coa drosophila melanogaster 1100.0 1100.0 1 PMID:21320074 -4.2.1.119 (2e)-decenoyl-coa rattus norvegicus 26.0 26.0 1 * -4.2.1.119 (2e)-hexenoyl-coa drosophila melanogaster 210.0 210.0 1 PMID:21320074 -4.2.1.119 (2e)-hexenoyl-coa rattus norvegicus 22.8 22.8 1 * -4.2.1.119 crotonyl-coa rattus norvegicus 2.3 2.3 1 * -4.2.1.120 4-hydroxybutanoyl-coa metallosphaera sedula 2.1 2.1 1 PMID:24532060 -4.2.1.121 (9s,10e,12z)-9-hydroperoxy-10,12-octadecadienoate solanum lycopersicum 890.0 890.0 1 PMID:11060314 -4.2.1.121 (9s,10e,12z,15z)-9-hydroperoxy-10,12,15-octadecatrienoate solanum lycopersicum 500.0 500.0 1 PMID:11060314 -4.2.1.122 indole thermococcus kodakarensis 3.46 1.04 3 PMID:24835339 -4.2.1.122 indole thermotoga maritima 0.46 0.46 1 PMID:11756459 -4.2.1.122 l-serine salmonella enterica subsp. enterica serovar typhimurium 0.35 0.35 1 PMID:28005309 -4.2.1.122 l-serine thermotoga maritima 0.44 0.44 1 PMID:11756459 -4.2.1.122 l-threonine salmonella enterica subsp. enterica serovar typhimurium 0.00068 0.00068 1 PMID:28005309 -4.2.1.126 n-acetylmuramate 6-phosphate escherichia coli 5.7 5.7 1 PMID:18837509 -4.2.1.127 (3s)-linalool castellaniella defragrans 0.073 0.073 1 * -4.2.1.127 myrcene castellaniella defragrans 0.15 0.15 1 * -4.2.1.129 squalene alicyclobacillus acidocaldarius 0.163 0.163 1 PMID:15056909 -4.2.1.130 2-oxoethanal escherichia coli 0.42 0.285 2 PMID:26774339 -4.2.1.130 2-oxopropanal escherichia coli 1.43 0.29 3 PMID:21696459;PMID:26774339 -4.2.1.130 methylglyoxal escherichia coli 2.61 2.61 1 PMID:21696459 -4.2.1.130 methylglyoxal homo sapiens 0.261 0.1485 4 PMID:37060572 -4.2.1.130 methylglyoxal saccharomyces cerevisiae 1.25 1.25 1 PMID:24758716 -4.2.1.130 methylglyoxal schizosaccharomyces pombe 1.43 0.967 3 PMID:24758716 -4.2.1.130 methylglyoxyl guanosine 5'-monophosphate homo sapiens 0.101 0.101 1 PMID:37060572 -4.2.1.130 methylglyoxyl n-acetylcysteine homo sapiens 0.109 0.109 1 PMID:37060572 -4.2.1.130 phenylglyoxal homo sapiens 0.0272 0.0234 3 PMID:25283443;PMID:37060572 -4.2.1.135 udp-n-acetyl-alpha-d-glucosamine campylobacter jejuni 0.118 0.118 1 PMID:17087520 -4.2.1.136 (6s)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide arabidopsis thaliana 0.26 0.26 1 PMID:24599492 -4.2.1.136 (6s)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide zea mays 0.3 0.3 1 PMID:24599492 -4.2.1.136 (6s)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate arabidopsis thaliana 0.34 0.34 1 PMID:24599492 -4.2.1.136 (6s)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate zea mays 0.38 0.38 1 PMID:24599492 -4.2.1.139 (3r,4r)-7,2'-dihydroxy-4'-methoxyisoflavanol glycyrrhiza echinata 59.9 59.9 1 PMID:32565424 -4.2.1.139 (3r,4r)-7,2'-dihydroxy-4'-methoxyisoflavanol lathyrus oleraceus 50.5 50.5 1 PMID:32565424 -4.2.1.139 (3s,4r)-7,2'-dihydroxy-4'-methoxyisoflavanol glycyrrhiza echinata 15.9 15.9 1 PMID:32565424 -4.2.1.139 (3s,4r)-7,2'-dihydroxy-4'-methoxyisoflavanol lathyrus oleraceus 3.3 3.3 1 PMID:32565424 -4.2.1.140 d-galactonate saccharolobus solfataricus 1.08 1.08 1 PMID:15474024 -4.2.1.140 d-gluconate saccharolobus solfataricus 10.4 10.4 1 PMID:15474024 -4.2.1.143 versiconal aspergillus parasiticus 2.1 2.1 1 PMID:8995367 -4.2.1.143 versiconal hemiacetal aspergillus parasiticus 2.5 2.5 1 PMID:8784203 -4.2.1.148 (2r,3s)-2-methylmalyl-coa cereibacter sphaeroides 1900.0 1900.0 1 PMID:18065535 -4.2.1.148 (2r,3s)-2-methylmalyl-coa chloroflexus aurantiacus 1700.0 1700.0 1 PMID:18065535 -4.2.1.150 crotonyl-coa meiothermus ruber 14.9 14.9 1 * -4.2.1.150 crotonyl-coa metallosphaera sedula 19.0 19.0 1 PMID:24532060 -4.2.1.151 chorismate thermus thermophilus 1.27 1.27 1 PMID:24083939 -4.2.1.154 tetracenomycin f2 streptomyces glaucescens 0.142 0.142 1 PMID:15231835 -4.2.1.156 l-talarate salmonella enterica subsp. enterica serovar typhimurium 2.1 2.1 1 PMID:17649980 -4.2.1.158 galactarate oceanobacillus iheyensis 6.8 6.8 1 PMID:19883118 -4.2.1.164 dtdp-4-dehydro-2,6-dideoxy-alpha-d-glucose saccharopolyspora spinosa 0.043 0.043 1 PMID:18345667 -4.2.1.167 (r)-2-hydroxyglutaryl-coa [clostridium] symbiosum 82.0 82.0 1 PMID:21434666 -4.2.1.17 (s)-3-hydroxybutyryl-coa metallosphaera sedula 15.0 15.0 1 PMID:24532060 -4.2.1.17 (z)-2-butenoyl-coa rattus norvegicus 152.0 152.0 1 * -4.2.1.17 3-oxo-chol-4,22-diene-24-oyl-coa mycobacterium tuberculosis 181.2 113.44999999999999 2 PMID:32649175 -4.2.1.17 crotonoyl-coa metallosphaera sedula 19.0 19.0 1 PMID:24532060 -4.2.1.17 crotonyl-coa bos taurus 5667.0 5667.0 1 PMID:5057465 -4.2.1.17 crotonyl-coa rattus norvegicus 2238.0 2014.0 2 PMID:10074351;PMID:12379132 -4.2.1.17 octenoyl-coa mycobacterium tuberculosis 1.2 1.2 1 PMID:32649175 -4.2.1.17 trans-2-decenoyl-coa rattus norvegicus 203.0 203.0 1 PMID:10074351 -4.2.1.17 trans-2-hexenoyl-coa rattus norvegicus 745.0 745.0 1 PMID:10074351 -4.2.1.171 cis-3-hydroxy-l-proline agrobacterium tumefaciens 20.0 20.0 1 PMID:28559297 -4.2.1.171 cis-3-hydroxy-l-proline azospirillum brasilense 2.4 2.4 1 PMID:28559297 -4.2.1.171 cis-3-hydroxy-l-proline micromonospora viridifaciens 47.0 11.2 4 PMID:28559297 -4.2.1.171 cis-3-hydroxy-l-proline pseudomonas aeruginosa 47.0 47.0 1 PMID:28559297 -4.2.1.171 cis-3-hydroxy-l-proline roseibium aggregatum 23.0 23.0 1 PMID:25608448 -4.2.1.172 trans-4-hydroxy-l-proline clostridioides difficile 46.0 45.5 2 PMID:28183913;PMID:32180548 -4.2.1.176 d-gulonate roseibium aggregatum 3.0 3.0 1 PMID:24831290 -4.2.1.176 l-lyxonate roseibium aggregatum 2.0 2.0 1 PMID:24831290 -4.2.1.177 (2s)-2,3-dihydroxypropane-1-sulfonate klebsiella oxytoca 130.0 130.0 1 PMID:32571930 -4.2.1.179 4-nitrophenyl alpha-d-arabinofuranoside bifidobacterium dentium 127.5 127.5 1 PMID:34688653 -4.2.1.18 (e)-3-methylglutaconyl-coa homo sapiens 5.1 5.1 1 PMID:16640564 -4.2.1.18 (e)-glutaconyl-coa acinetobacter sp. 18.0 18.0 1 PMID:16482430 -4.2.1.18 (e)-glutaconyl-coa homo sapiens 1.4 1.4 1 PMID:16640564 -4.2.1.18 (r,s)-3-hydroxy-3-methylglutaryl-coa homo sapiens 0.26 0.26 1 PMID:16640564 -4.2.1.18 (s)-3-hydroxy-3-methylglutaryl-coa acinetobacter sp. 60.0 60.0 1 PMID:16482430 -4.2.1.18 (s)-3-hydroxy-3-methylglutaryl-coa arabidopsis thaliana 23.4 23.4 1 PMID:29742810 -4.2.1.18 (s)-3-hydroxyglutaryl-coa acinetobacter sp. 13.0 13.0 1 PMID:16482430 -4.2.1.18 3-hydroxybutyryl-coa homo sapiens 1.7 1.7 1 PMID:16640564 -4.2.1.18 3-methylcrotonyl-coa homo sapiens 2.9 2.9 1 PMID:16640564 -4.2.1.18 3-methylglutaconyl-coa acinetobacter sp. 138.0 138.0 1 PMID:16482430 -4.2.1.18 crotonyl-coa homo sapiens 6.8 6.8 1 PMID:16640564 -4.2.1.18 trans-3-methylglutaconyl-coa pseudomonas putida 2.1 2.1 1 PMID:15096032 -4.2.1.182 (r)-5-phosphomevalonate aeropyrum pernix 15.2 15.2 1 PMID:36992929 -4.2.1.183 (13s)-hpod asparagus officinalis 818.8 818.8 1 PMID:35460712 -4.2.1.183 (13s)-hpot asparagus officinalis 181.3 181.3 1 PMID:35460712 -4.2.1.183 (9s)-hpod asparagus officinalis 375.0 375.0 1 PMID:35460712 -4.2.1.183 (9s)-hpot asparagus officinalis 482.5 482.5 1 PMID:35460712 -4.2.1.183 (9z,11e,13s)-13-hydroperoxy-9,11-octadecadienoic acid ranunculus acris 67.7 67.7 1 PMID:24863619 -4.2.1.183 (9z,11e,13s)-13-hydroperoxy-9,11-octadecadienoic acid selaginella moellendorffii 193.5 193.5 1 PMID:26776054 -4.2.1.183 (9z,11e,13s,15z)-13-hydroperoxy-9,11,15-octadecatrienate ranunculus acris 134.0 134.0 1 PMID:24863619 -4.2.1.183 (9z,11e,13s,15z)-13-hydroperoxy-9,11,15-octadecatrienoic acid selaginella moellendorffii 266.7 266.7 1 PMID:26776054 -4.2.1.19 d-erythro-1-(imidazol-4-yl)glycerol 3-phosphate mycobacterium tuberculosis 1400.0 1400.0 1 PMID:24311587 -4.2.1.2 (s)-malate bacteria 540.0 540.0 1 PMID:8593099 -4.2.1.2 (s)-malate corynebacterium glutamicum 460.0 155.0 6 PMID:16717409 -4.2.1.2 (s)-malate cyanidioschyzon merolae 244.0 244.0 1 PMID:33042040 -4.2.1.2 (s)-malate escherichia coli 11.2 11.2 1 PMID:8203917 -4.2.1.2 (s)-malate homo sapiens 370.0 245.0 5 PMID:30761759 -4.2.1.2 (s)-malate leishmania major 537.0 450.5 2 PMID:31743022 -4.2.1.2 (s)-malate pelotomaculum thermopropionicum 25.2 25.2 1 PMID:17319878 -4.2.1.2 (s)-malate plasmodium falciparum 159.0 159.0 1 PMID:29449371 -4.2.1.2 (s)-malate schistosoma mansoni 19.0 19.0 1 PMID:33549669 -4.2.1.2 (s)-malate synechocystis sp. 6803 42.0 42.0 1 PMID:31337820 -4.2.1.2 (s)-malate thermosynechococcus vestitus 15.0 15.0 1 PMID:33042040 -4.2.1.2 fumarate bacteria 690.0 690.0 1 PMID:8593099 -4.2.1.2 fumarate corynebacterium glutamicum 730.0 580.0 6 PMID:16717409 -4.2.1.2 fumarate cyanidioschyzon merolae 235.0 235.0 1 PMID:33042040 -4.2.1.2 fumarate escherichia coli 1150.0 1149.0 3 PMID:12021453;PMID:8203917 -4.2.1.2 fumarate homo sapiens 370.0 175.0 7 PMID:30761759 -4.2.1.2 fumarate leishmania major 1500.0 126.39999999999999 6 PMID:22569531;PMID:31743022 -4.2.1.2 fumarate pelotomaculum thermopropionicum 219.0 219.0 1 PMID:17319878 -4.2.1.2 fumarate plasmodium falciparum 182.0 182.0 1 PMID:29449371 -4.2.1.2 fumarate schistosoma mansoni 49.0 49.0 1 PMID:33549669 -4.2.1.2 fumarate synechocystis sp. 6803 100.0 100.0 1 PMID:31337820 -4.2.1.2 fumarate thermosynechococcus vestitus 37.0 37.0 1 PMID:33042040 -4.2.1.2 l-malate homo sapiens 150.0 150.0 1 PMID:29456767 -4.2.1.2 l-malate rhizopus arrhizus 0.055 0.055 1 PMID:27711153 -4.2.1.2 l-malate streptomyces lividans 620.0 267.0 3 PMID:24307253 -4.2.1.2 mesaconate plasmodium falciparum 60.0 60.0 1 PMID:29449371 -4.2.1.2 s-malate leishmania major 151.4 18.9 4 PMID:22569531 -4.2.1.20 1-(indol-3-yl)glycerol 3-phosphate salmonella enterica subsp. enterica serovar typhimurium 6.0 1.4549999999999998 6 PMID:11412095;PMID:12460570;PMID:3314989 -4.2.1.20 1-(indol-3-yl)glycerol 3-phosphate thermotoga maritima 5.6 2.887 2 PMID:11756459 -4.2.1.20 1-c-(indol-3-yl)glycerol 3-phosphate escherichia coli 0.00029 0.00029 1 PMID:34124159 -4.2.1.20 indole arabidopsis thaliana 0.007 0.007 1 PMID:20701934 -4.2.1.20 indole archaeoglobus fulgidus 0.074 0.074 1 PMID:27510733 -4.2.1.20 indole escherichia coli 3.81 0.16 3 PMID:25377949;PMID:27510733;PMID:34124159 -4.2.1.20 indole mycobacterium tuberculosis 70.29 70.29 1 PMID:19430702 -4.2.1.20 indole pyrococcus furiosus 1.0 0.31 3 PMID:26553994;PMID:27510733 -4.2.1.20 indole salmonella enterica subsp. enterica serovar typhimurium 10.1 4.27 11 PMID:12460570;PMID:12820890;PMID:15811341;PMID:3314989;PMID:7626616 -4.2.1.20 indole thermococcus kodakarensis 3.46 2.25 2 PMID:24835339 -4.2.1.20 indole thermotoga maritima 10.0 4.2 3 PMID:11756459;PMID:27510733 -4.2.1.20 indole zea mays 0.0102 0.0102 1 PMID:20701934 -4.2.1.20 l-ser salmonella enterica subsp. enterica serovar typhimurium 5.4 5.4 1 PMID:3314989 -4.2.1.20 l-serine arabidopsis thaliana 0.016 0.01575 2 PMID:20701934;PMID:25184516 -4.2.1.20 l-serine chlamydia trachomatis 0.35 0.22399999999999998 2 PMID:34107106 -4.2.1.20 l-serine escherichia coli 2.83 0.38 5 PMID:32260519;PMID:34097254;PMID:34124159 -4.2.1.20 l-serine mycobacterium tuberculosis 48.21 48.21 1 PMID:19430702 -4.2.1.20 l-serine pyrococcus furiosus 1.0 1.0 1 PMID:27935677 -4.2.1.20 l-serine saccharolobus solfataricus 0.2 0.116 2 PMID:25184516 -4.2.1.20 l-serine salmonella enterica subsp. enterica serovar typhimurium 14.0 3.05 28 PMID:11412095;PMID:12460570;PMID:15811341;PMID:17927213;PMID:28005309;PMID:34595921 -4.2.1.20 l-serine thermotoga maritima 8.0 3.8 3 PMID:11756459;PMID:25184516 -4.2.1.20 l-serine zea mays 0.0223 0.0223 1 PMID:20701934 -4.2.1.20 l-threonine pyrococcus furiosus 0.61 0.61 1 PMID:27935677 -4.2.1.20 l-threonine salmonella enterica subsp. enterica serovar typhimurium 0.0007 0.0007 1 PMID:28005309 -4.2.1.20 o-phospho-l-serine arabidopsis thaliana 0.015 0.015 1 PMID:25184516 -4.2.1.20 o-phospho-l-serine saccharolobus solfataricus 0.3 0.1575 2 PMID:25184516 -4.2.1.20 o-phospho-l-serine thermotoga maritima 0.414 0.414 1 PMID:25184516 -4.2.1.20 serine salmonella enterica subsp. enterica serovar typhimurium 0.06 0.06 1 PMID:3314989 -4.2.1.22 h2s homo sapiens 0.78 0.565 2 PMID:28874062 -4.2.1.22 homocysteine homo sapiens 34.0 20.1 2 PMID:11524006 -4.2.1.22 homocysteine saccharomyces cerevisiae 7.38 7.38 1 PMID:8017103 -4.2.1.22 l-cystathionine saccharomyces cerevisiae 6.08 1.03 5 PMID:12525186;PMID:14967036;PMID:19264153 -4.2.1.22 l-cysteine homo sapiens 31.34 3.13 10 PMID:15520012;PMID:16619244;PMID:28874062;PMID:35864237 -4.2.1.22 l-cysteine lactiplantibacillus plantarum 7.6 4.35 2 PMID:28127810 -4.2.1.22 l-homocysteine bacillus anthracis 8.39 5.885 2 PMID:28921884 -4.2.1.22 l-homocysteine homo sapiens 26.78 6.295 10 PMID:16619244;PMID:18060852;PMID:19010420;PMID:28874062 -4.2.1.22 l-homocysteine saccharomyces cerevisiae 21.5 19.25 2 PMID:12525186;PMID:19264153 -4.2.1.22 l-ser saccharomyces cerevisiae 7.97 7.97 1 PMID:8017103 -4.2.1.22 l-serine homo sapiens 39.0 3.67 20 PMID:10529187;PMID:11524006;PMID:15520012;PMID:15958186;PMID:16619244;PMID:18060852;PMID:19010420;PMID:28874062;PMID:35864237 -4.2.1.22 l-serine saccharomyces cerevisiae 21.5 16.8 5 PMID:10956046;PMID:11948191;PMID:14967036;PMID:19264153 -4.2.1.22 l-serine toxoplasma gondii 6.3 6.0 2 PMID:35897745 -4.2.1.22 o-acetyl-l-serine toxoplasma gondii 5.6 5.55 2 PMID:35897745 -4.2.1.24 5-aminolevulinic acid pseudomonas aeruginosa 16.1 16.1 1 PMID:19822707 -4.2.1.28 1,2-butanediol klebsiella oxytoca 7.8 7.8 1 PMID:18586770 -4.2.1.28 1,2-butanediol klebsiella pneumoniae 7.2 7.2 1 PMID:1267798 -4.2.1.28 1,2-ethanediol klebsiella pneumoniae 286.0 286.0 1 PMID:1267798 -4.2.1.28 1,2-propanediol klebsiella oxytoca 366.0 366.0 1 PMID:18586770 -4.2.1.28 1,2-propanediol klebsiella pneumoniae 337.0 337.0 1 PMID:1267798 -4.2.1.28 2,3-butanediol klebsiella pneumoniae 15.1 9.55 2 PMID:1267798;PMID:380560 -4.2.1.28 cn-cobalamin klebsiella oxytoca 336.0 336.0 1 PMID:19016846 -4.2.1.28 glycerol klebsiella pneumoniae 371.0 344.0 2 PMID:1267798;PMID:321014 -4.2.1.28 propane-1,2-diol klebsiella oxytoca 354.0 345.0 2 PMID:18260646;PMID:29797764 -4.2.1.3 cis-aconitate homo sapiens 23.8 23.8 1 PMID:36738801 -4.2.1.3 cis-aconitate plasmodium falciparum 3.3 3.3 1 PMID:15963579 -4.2.1.3 cis-aconitate salmonella enterica subsp. enterica serovar typhimurium 5.2 5.2 1 PMID:23637460 -4.2.1.3 citrate homo sapiens 10.2 10.2 1 PMID:36738801 -4.2.1.3 citrate salmonella enterica subsp. enterica serovar typhimurium 5.3 5.3 1 PMID:23637460 -4.2.1.3 citrate synechocystis sp. pcc 6803 9.12 7.28 7 PMID:34429477 -4.2.1.3 isocitrate homo sapiens 14.1 14.1 1 PMID:36738801 -4.2.1.3 isocitrate salmonella enterica subsp. enterica serovar typhimurium 1.1 1.1 1 PMID:23637460 -4.2.1.3 isocitrate synechocystis sp. pcc 6803 16.67 9.02 7 PMID:34429477 -4.2.1.30 (r)-1,2-propanediol klebsiella pneumoniae 200.0 200.0 1 PMID:28881100 -4.2.1.30 glycerol klebsiella pneumoniae 860.0 430.0 3 PMID:12230560;PMID:22042303;PMID:28052817 -4.2.1.30 meso-2,3-butanediol klebsiella pneumoniae 3.4 3.4 1 PMID:28881100 -4.2.1.30 pentane-1,2-diol klebsiella pneumoniae 200.0 200.0 1 PMID:22042303 -4.2.1.30 propane-1,2-diol klebsiella pneumoniae 392.0 392.0 1 PMID:12230560 -4.2.1.36 (z)-but-1-ene-1,2,4-tricarboxylate methanocaldococcus jannaschii 0.75 0.75 1 PMID:20170198 -4.2.1.36 (z)-hex-1-ene-1,2,6-tricarboxylate methanocaldococcus jannaschii 2.5 2.5 1 PMID:20170198 -4.2.1.36 (z)-pent-1-ene-1,2,5-tricarboxylate methanocaldococcus jannaschii 0.66 0.66 1 PMID:20170198 -4.2.1.39 d-gluconate saccharolobus solfataricus 760.0 760.0 1 PMID:15509194 -4.2.1.40 4-deoxy-4-fluoro-d-glucarate escherichia coli 44.0 44.0 1 PMID:11513584 -4.2.1.40 d-glucarate acinetobacter baylyi 6.39 6.39 1 PMID:18364348 -4.2.1.40 d-glucarate escherichia coli 35.0 27.5 2 PMID:10769114;PMID:11513584;PMID:9772162 -4.2.1.40 d-glucarate pseudomonas putida 17.0 10.0 2 PMID:9772160 -4.2.1.40 l-idarate escherichia coli 35.0 34.0 3 PMID:10769114;PMID:11513584;PMID:9772162 -4.2.1.40 l-idarate pseudomonas putida 21.0 12.5 2 PMID:9772160 -4.2.1.41 5-dehydro-4-deoxy-d-glucarate acinetobacter baylyi 4.5 4.2 2 PMID:18364348;PMID:27855668 -4.2.1.41 5-dehydro-4-deoxy-d-glucarate agrobacterium fabrum 8.83 8.83 1 PMID:25454257 -4.2.1.41 5-dehydro-4-deoxy-d-glucarate comamonas testosteroni 3.1 3.1 2 PMID:27855668 -4.2.1.41 5-dehydro-4-deoxy-d-glucarate polaromonas naphthalenivorans 1.7 1.7 1 PMID:27855668 -4.2.1.41 5-dehydro-4-deoxy-d-glucarate polaromonas naphthalenivorans cj2 1.7 1.7 1 PMID:27855668 -4.2.1.42 galactarate escherichia coli 22.0 22.0 1 PMID:9772162 -4.2.1.42 galactarate oceanobacillus iheyensis 6.8 6.8 1 PMID:19883118 -4.2.1.42 galactarate salmonella enterica subsp. enterica serovar typhimurium 4.8 4.2 2 PMID:17649980;PMID:29248502 -4.2.1.42 meso-galactarate agrobacterium tumefaciens 0.12 0.12 1 PMID:24926996 -4.2.1.42 meso-galactarate salmonella enterica subsp. enterica serovar typhimurium 4.8 4.8 1 PMID:29248502 -4.2.1.43 2-dehydro-3-deoxy-d-arabinonate azospirillum brasilense 0.19 0.19 1 PMID:32697085 -4.2.1.43 2-dehydro-3-deoxy-l-arabinonate azospirillum brasilense 39.2 26.400000000000002 2 PMID:32566996;PMID:32697085 -4.2.1.43 2-dehydro-3-deoxy-l-arabinonate cupriavidus necator 23.4 23.4 1 PMID:32566996 -4.2.1.43 2-dehydro-3-deoxy-l-arabinonate herbaspirillum seropedicae 29.6 29.6 1 PMID:32566996 -4.2.1.43 2-dehydro-3-deoxy-l-arabinonate variovorax paradoxus 21.8 21.8 1 PMID:32566996 -4.2.1.45 cdp-d-glucose yersinia pseudotuberculosis 3.69 3.69 1 PMID:8664262 -4.2.1.46 dtdp-6-fluoro-6-deoxyglucose escherichia coli 0.044 0.044 1 PMID:11601973 -4.2.1.46 dtdp-alpha-d-glucose acanthamoeba polyphaga mimivirus 0.18 0.18 1 PMID:32083779 -4.2.1.46 dtdp-alpha-d-glucose mycobacterium tuberculosis 466.6 466.6 1 PMID:26778528 -4.2.1.46 dtdp-alpha-d-glucose saccharothrix syringae 11.2 11.2 2 PMID:34819927 -4.2.1.46 dtdp-alpha-d-glucose streptomyces venezuelae 3.08 3.08 1 PMID:32083779 -4.2.1.46 dtdp-glucose escherichia coli 4.9 4.9 3 PMID:11380254;PMID:11478886;PMID:11601973 -4.2.1.46 udp-alpha-d-glucose acanthamoeba polyphaga mimivirus 0.27 0.27 1 PMID:32083779 -4.2.1.46 udp-alpha-d-glucose streptomyces venezuelae 0.014 0.014 1 PMID:32083779 -4.2.1.46 udp-glucose escherichia coli 0.024 0.024 1 PMID:11380254 -4.2.1.47 gdp-alpha-d-mannose burkholderia cepacia 1.0 1.0 1 PMID:23460819 -4.2.1.47 gdp-alpha-d-mannose homo sapiens 0.42 0.42 1 PMID:30984471 -4.2.1.47 gdp-mannose escherichia coli 5.0 5.0 1 PMID:10673432 -4.2.1.47 gdp-mannose homo sapiens 0.8 0.8 1 PMID:10462046 -4.2.1.47 gdp-mannose mortierella alpina 5.96 5.96 2 PMID:20035716 -4.2.1.47 gdp-mannose pseudomonas aeruginosa 8.82 8.82 1 PMID:19459932 -4.2.1.48 5-oxo-d-proline mus musculus 7.67 7.67 1 PMID:30003876 -4.2.1.48 d-glutamate mus musculus 35.6 18.125 2 PMID:30003876;PMID:32702438 -4.2.1.5 d-altronate herbaspirillum huttiense 0.93 0.93 1 PMID:30985034 -4.2.1.5 d-arabinonate herbaspirillum huttiense 9.38 9.38 1 PMID:30985034 -4.2.1.5 d-arabinonate saccharolobus solfataricus 1.8 1.8 1 PMID:16849334 -4.2.1.5 d-idonate herbaspirillum huttiense 0.27 0.27 1 PMID:30985034 -4.2.1.5 l-fuconate herbaspirillum huttiense 0.2 0.2 1 PMID:30985034 -4.2.1.5 l-gluconate herbaspirillum huttiense 0.5 0.5 1 PMID:30985034 -4.2.1.5 l-xylonate herbaspirillum huttiense 6.0 6.0 1 PMID:30985034 -4.2.1.51 prephenate corynebacterium glutamicum 0.12 0.12 1 PMID:14749915 -4.2.1.51 prephenate escherichia coli 32.0 32.0 2 PMID:10769128 -4.2.1.51 prephenate methanocaldococcus jannaschii 12.3 12.3 1 PMID:17115705 -4.2.1.51 prephenate pinus pinaster 0.7158 0.04 6 PMID:27125254 -4.2.1.51 prephenate saccharomyces cerevisiae 820.9 737.0 2 * -4.2.1.53 alpha-linolenic acid macrococcoides caseolyticum 0.13 0.13 1 PMID:22203098 -4.2.1.53 gamma-linolenate lysinibacillus fusiformis 2.17 2.17 1 PMID:22189865 -4.2.1.53 gamma-linolenic acid macrococcoides caseolyticum 2.67 2.67 1 PMID:22203098 -4.2.1.53 linoleate lysinibacillus fusiformis 1.33 1.33 1 PMID:22189865 -4.2.1.53 linoleic acid macrococcoides caseolyticum 0.13 0.13 1 PMID:22203098 -4.2.1.53 myristoleic acid macrococcoides caseolyticum 0.03 0.03 1 PMID:22203098 -4.2.1.53 oleate lysinibacillus fusiformis 14.17 14.17 1 PMID:22189865 -4.2.1.53 oleate rhodococcus erythropolis 34.0 34.0 1 * -4.2.1.53 oleate stenotrophomonas maltophilia 11.83 11.83 1 PMID:22261174 -4.2.1.53 oleic acid macrococcoides caseolyticum 7.83 7.83 1 PMID:22203098 -4.2.1.53 oleic acid paracoccus aminophilus 6.95 6.95 1 PMID:34112373 -4.2.1.53 palmitoleate lysinibacillus fusiformis 7.17 7.17 1 PMID:22189865 -4.2.1.53 palmitoleic acid macrococcoides caseolyticum 3.83 3.83 1 PMID:22203098 -4.2.1.68 d-arabinonate xanthomonas campestris 2.4 2.4 1 PMID:17144652 -4.2.1.68 l-fuconate xanthomonas campestris 15.0 15.0 1 PMID:17144652 -4.2.1.68 l-galactonate xanthomonas campestris 0.9 0.9 1 PMID:17144652 -4.2.1.69 cyanamide saccharomyces cerevisiae 9.8 9.8 1 PMID:31152065 -4.2.1.7 d-altronate paracidovorax avenae 0.35 0.35 1 PMID:30985034 -4.2.1.7 d-arabinonate paracidovorax avenae 3.23 3.23 1 PMID:30985034 -4.2.1.7 d-idonate paracidovorax avenae 0.071 0.071 1 PMID:30985034 -4.2.1.7 l-fuconate paracidovorax avenae 0.082 0.082 1 PMID:30985034 -4.2.1.7 l-gluconate paracidovorax avenae 0.071 0.071 1 PMID:30985034 -4.2.1.7 l-xylonate paracidovorax avenae 0.67 0.67 1 PMID:30985034 -4.2.1.70 trnaile saccharomyces cerevisiae 0.00833 0.00833 1 PMID:10356324 -4.2.1.70 trnaval saccharomyces cerevisiae 0.00833 0.0075 2 PMID:10356324 -4.2.1.75 hydroxymethylbilane bacillus subtilis 4.6 4.6 1 PMID:7628476 -4.2.1.75 hydroxymethylbilane escherichia coli 500.0 500.0 1 PMID:2557837 -4.2.1.75 hydroxymethylbilane homo sapiens 890.0 30.0 3 PMID:15496592;PMID:24925316;PMID:3805019 -4.2.1.76 dtdp-d-glucose trichomonas vaginalis 0.36 0.36 1 PMID:36498914 -4.2.1.76 udp-d-glucose arabidopsis thaliana 2860.0 2860.0 1 PMID:17190829 -4.2.1.76 udp-d-glucose trichomonas vaginalis 0.39 0.39 1 PMID:36498914 -4.2.1.77 trans-3-hydroxy-l-proline azospirillum brasilense 37.33 37.33 1 PMID:28559297 -4.2.1.77 trans-3-hydroxy-l-proline colwellia psychrerythraea 22.17 22.17 1 PMID:28559297 -4.2.1.77 trans-3-hydroxy-l-proline micromonospora viridifaciens 3.4 3.4 1 PMID:28559297 -4.2.1.78 4-biphenylaldehyde thalictrum flavum subsp. glaucum 0.001 0.001 1 PMID:38647611 -4.2.1.78 benzaldehyde thalictrum flavum subsp. glaucum 0.237 0.237 1 PMID:38647611 -4.2.1.79 2-methylcitrate escherichia coli 0.045 0.045 1 PMID:36097012 -4.2.1.79 cis-aconitate escherichia coli 119.0 119.0 1 PMID:36097012 -4.2.1.79 citrate escherichia coli 10562.0 10562.0 1 PMID:36097012 -4.2.1.8 d-mannonate chromohalobacter israelensis 1.6 1.6 1 PMID:25145794 -4.2.1.8 d-mannonate escherichia coli 0.81 0.81 1 PMID:22796868 -4.2.1.8 d-mannonate streptococcus suis 5.88 5.88 1 PMID:19617363 -4.2.1.8 d-mannonate thermoplasma acidophilum 1.64 1.64 1 * -4.2.1.8 d-mannono-1,4-lactone thermoplasma acidophilum 1.33 1.33 1 * -4.2.1.80 2-hydroxyhexa-2,4-dienoate paraburkholderia xenovorans 60.5 60.5 1 PMID:15691330 -4.2.1.80 2-hydroxypent-2,4-dienoate paraburkholderia xenovorans 361.0 288.0 2 PMID:15691330 -4.2.1.80 5-chloro-2-hydroxypent-2,4-dienoate paraburkholderia xenovorans 7.7 7.7 1 PMID:15691330 -4.2.1.81 (s,s)-tartrate bradyrhizobium japonicum 7.3 7.3 1 PMID:17144653 -4.2.1.81 d-tartrate cereibacter sphaeroides 19.8 19.8 1 PMID:6978882 -4.2.1.83 4-oxalomesaconate phytopseudomonas straminea 75.4 38.85 2 PMID:17284837 -4.2.1.84 (r)-mandelonitrile rhodococcus rhodochrous 0.74 0.74 1 PMID:29080350 -4.2.1.84 (s)-mandelonitrile rhodococcus rhodochrous 1.2 1.2 1 PMID:29080350 -4.2.1.84 2-cyanobenzamide rhodococcus rhodochrous 145.6 145.6 1 * -4.2.1.84 2-cyanopyridine aeribacillus pallidus 443.3 443.3 1 * -4.2.1.84 3-cyanopyridine aeribacillus pallidus 629.6 323.45 2 * -4.2.1.84 3-cyanopyridine caldalkalibacillus thermarum 352.1 235.75 2 PMID:33749895;PMID:34454178 -4.2.1.84 3-cyanopyridine pseudomonas putida 720.6 720.6 1 * -4.2.1.84 3-cyanopyridine pseudonocardia thermophila 131.0 131.0 2 PMID:14717710 -4.2.1.84 3-cyanopyridine sinorhizobium meliloti 1054.36 1054.36 1 * -4.2.1.84 3-cyanopyridine streptomyces rimosus 79.0 57.0 6 PMID:24914472 -4.2.1.84 4-cyanobenzamide rhodococcus rhodochrous 107.7 107.7 1 * -4.2.1.84 4-cyanopyridine aeribacillus pallidus 59.05 59.05 1 * -4.2.1.84 4-cyanopyridine pseudonocardia thermophila 90.0 90.0 2 PMID:14717710 -4.2.1.84 5-cyanovaleramide rhodococcus rhodochrous 435.7 435.7 1 * -4.2.1.84 acetamiprid sinorhizobium meliloti 1.04 1.04 1 * -4.2.1.84 acetonitrile bacillus sp. (in: firmicutes) 12.4 12.4 1 PMID:9783183 -4.2.1.84 acetonitrile rhodococcus sp. (in: high g+c gram-positive bacteria) 41.0 41.0 1 PMID:17635193 -4.2.1.84 acrylonitrile comamonas testosteroni 1100.0 1100.0 1 PMID:26077812 -4.2.1.84 acrylonitrile monosiga brevicollis 130.0 130.0 1 PMID:27693250 -4.2.1.84 acrylonitrile pseudonocardia thermophila 1910.0 1910.0 2 PMID:14717710 -4.2.1.84 acrylonitrile rhodococcus sp. (in: high g+c gram-positive bacteria) 8.0 8.0 1 PMID:17635193 -4.2.1.84 adiponitrile rhodococcus erythropolis 184.7 184.7 1 PMID:36456206 -4.2.1.84 benzonitrile monosiga brevicollis 33.0 33.0 1 PMID:27693250 -4.2.1.84 benzonitrile pseudonocardia thermophila 123.0 123.0 2 PMID:14717710 -4.2.1.84 benzonitrile sinorhizobium meliloti 1489.82 1489.82 1 * -4.2.1.84 butyronitrile rhodococcus sp. (in: high g+c gram-positive bacteria) 0.99 0.99 1 PMID:17635193 -4.2.1.84 cyanoacetamide rhodococcus rhodochrous 417.2 417.2 1 * -4.2.1.84 indole-3-acetonitrile sinorhizobium meliloti 426.68 426.68 1 * -4.2.1.84 methacrylonitrile pseudonocardia thermophila 1000.0 1000.0 2 PMID:14717710 -4.2.1.84 methacrylonitrile rhodococcus erythropolis 1.6e-05 1.6e-05 1 PMID:20221653 -4.2.1.84 methacrylonitrile rhodococcus sp. (in: high g+c gram-positive bacteria) 55000.0 55000.0 1 PMID:16636455 -4.2.1.84 n-valeronitrile pseudomonas putida 0.327 0.327 1 PMID:21473592 -4.2.1.84 propionitrile pseudomonas chlororaphis 30.7 30.7 1 PMID:3830164 -4.2.1.84 propionitrile rhodococcus sp. (in: high g+c gram-positive bacteria) 2.6 2.6 1 PMID:17635193 -4.2.1.84 thiacloprid sinorhizobium meliloti 131.36 131.36 1 * -4.2.1.84 toyocamycin streptomyces rimosus 159.0 79.72 6 PMID:24914472 -4.2.1.84 valeronitrile bacillus sp. (in: firmicutes) 76.3 76.3 1 PMID:9783183 -4.2.1.9 (2r)-2,3-dihydroxyisovalerate synechocystis sp. pcc 6803 0.47 0.47 1 PMID:32786290 -4.2.1.9 (2r,3r)-2,3-dihydroxy-3-methylpentanoate spinacia oleracea 12.3 10.3 2 * -4.2.1.9 (r)-2,3-dihydroxyisovalerate mycobacterium tuberculosis 1.87 1.87 1 PMID:31315931 -4.2.1.9 2,3-dihydroxy-3-methylbutanoate saccharolobus solfataricus 0.31 0.31 2 PMID:26102631 -4.2.1.9 2,3-dihydroxy-3-methylbutanoate spinacia oleracea 11.5 11.5 1 * -4.2.1.9 2,3-dihydroxybutanoate spinacia oleracea 4.6 4.6 1 * -4.2.1.9 2,3-dihydroxyisovalerate campylobacter jejuni 6.5 3.250175 2 PMID:35535733 -4.2.1.9 2,3-dihydroxyisovalerate saccharolobus solfataricus 75.8 75.8 1 PMID:16567425 -4.2.1.9 2,3-dihydroxyisovalerate spinacia oleracea 25.0 25.0 1 PMID:2831190 -4.2.1.9 2,3-dihydroxyisovalerate staphylococcus aureus 2.1 1.05038 2 PMID:35535733 -4.2.1.9 3-cyclopropyl-2,3-dihydroxybutanoate spinacia oleracea 5.7 5.7 1 * -4.2.1.9 d-gluconate saccharolobus solfataricus 48.5 0.7949999999999999 4 PMID:16567425;PMID:26102631;PMID:35546366 -4.2.1.9 d-glycerate saccharolobus solfataricus 0.051 0.03 3 PMID:26102631;PMID:35546366 -4.2.1.90 d-gulonate escherichia coli k-12 0.02 0.02 1 PMID:18754693 -4.2.1.90 l-lyxonate escherichia coli k-12 2.0 2.0 1 PMID:18754693 -4.2.1.90 l-lyxonate salmonella enterica subsp. enterica serovar typhimurium 0.05 0.05 1 PMID:18754693 -4.2.1.90 l-mannonate escherichia coli k-12 0.2 0.2 1 PMID:18754693 -4.2.1.90 l-mannonate salmonella enterica subsp. enterica serovar typhimurium 0.1 0.1 1 PMID:18754693 -4.2.1.90 l-rhamnonate azotobacter vinelandii 0.72 0.72 1 PMID:18505728 -4.2.1.90 l-rhamnonate escherichia coli k-12 3.2 3.2 1 PMID:18754693 -4.2.1.90 l-rhamnonate salmonella enterica subsp. enterica serovar typhimurium 3.9 3.9 1 PMID:18754693 -4.2.1.90 l-rhamnonate scheffersomyces stipitis 49.3 49.3 1 PMID:18505728 -4.2.1.91 l-arogenate arabidopsis thaliana 6.1 3.6 6 PMID:17726025 -4.2.1.91 l-arogenate petunia x hybrida 1.231 0.254 4 PMID:20215586;PMID:34403557 -4.2.1.91 prephenate arabidopsis thaliana 0.16 0.04 3 PMID:17726025 -4.2.1.91 prephenate petunia x hybrida 0.06 0.036 2 PMID:20215586 -4.2.1.92 (13s)-hydroperoxyoctadecadienoic acid oryza sativa 494.5 494.5 1 PMID:23527858 -4.2.1.92 (13s)-hydroperoxyoctadecatrienoic acid oryza sativa 537.8 537.8 1 PMID:23527858 -4.2.1.92 (9s)-hydroperoxyoctadecadienoic acid oryza sativa 44.9 44.9 1 PMID:23527858 -4.2.1.92 (9s)-hydroperoxyoctadecatrienoic acid oryza sativa 17.5 17.5 1 PMID:23527858 -4.2.1.92 (9s,10e,12z)-9-hydroperoxy-10,12-octadecadienoic acid cucumis sativus 676.4 565.85 2 PMID:29325723 -4.2.1.92 (9s,10e,12z)-9-hydroperoxy-10,12-octadecadienoic acid glycine max 228.6 228.6 1 PMID:29325723 -4.2.1.92 (9s,10e,12z)-9-hydroperoxy-10,12-octadecadienoic acid medicago truncatula 773.3 773.3 1 PMID:29325723 -4.2.1.92 (9s,10e,12z)-9-hydroperoxy-10,12-octadecadienoic acid solanum tuberosum 1115.9 1115.9 1 PMID:29325723 -4.2.1.92 (9s,10e,12z,15z)-9-hydroperoxy-10,12,15-octadecatrienoic acid cucumis sativus 375.4 356.5 2 PMID:29325723 -4.2.1.92 (9s,10e,12z,15z)-9-hydroperoxy-10,12,15-octadecatrienoic acid glycine max 173.8 173.8 1 PMID:29325723 -4.2.1.92 (9s,10e,12z,15z)-9-hydroperoxy-10,12,15-octadecatrienoic acid medicago truncatula 867.7 867.7 1 PMID:29325723 -4.2.1.92 (9s,10e,12z,15z)-9-hydroperoxy-10,12,15-octadecatrienoic acid solanum tuberosum 600.0 600.0 1 PMID:29325723 -4.2.1.92 (9z,11e,13s)-13-hydroperoxy-9,11-octadecadienoic acid cucumis sativus 752.4 674.4 2 PMID:29325723 -4.2.1.92 (9z,11e,13s)-13-hydroperoxy-9,11-octadecadienoic acid glycine max 290.0 290.0 1 PMID:29325723 -4.2.1.92 (9z,11e,13s)-13-hydroperoxy-9,11-octadecadienoic acid medicago truncatula 913.3 913.3 1 PMID:29325723 -4.2.1.92 (9z,11e,13s)-13-hydroperoxy-9,11-octadecadienoic acid olea europaea 133.9 44.45 6 PMID:26961190;PMID:28013430 -4.2.1.92 (9z,11e,13s)-13-hydroperoxy-9,11-octadecadienoic acid solanum tuberosum 1011.6 1011.6 1 PMID:29325723 -4.2.1.92 (9z,11e,13s,15z)-13-hydroperoxy-9,11,15-octadecatrienoic acid cucumis sativus 530.9 454.04999999999995 2 PMID:29325723 -4.2.1.92 (9z,11e,13s,15z)-13-hydroperoxy-9,11,15-octadecatrienoic acid medicago truncatula 768.9 768.9 1 PMID:29325723 -4.2.1.92 (9z,11e,13s,15z)-13-hydroperoxy-9,11,15-octadecatrienoic acid olea europaea 843.3 583.2 6 PMID:26961190;PMID:28013430 -4.2.1.93 (6s)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide arabidopsis thaliana 0.26 0.26 1 PMID:24599492 -4.2.1.93 (6s)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide zea mays 0.3 0.3 1 PMID:24599492 -4.2.1.93 (6s)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate arabidopsis thaliana 0.34 0.34 1 PMID:24599492 -4.2.1.93 (6s)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate zea mays 0.38 0.38 1 PMID:24599492 -4.2.1.94 scytalone pyricularia oryzae 70.0 38.2 3 PMID:15056895 -4.2.1.95 xanthohumol fusarium solani 4.77 4.77 1 PMID:29420618 -4.2.1.96 (6r)-6-(l-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin homo sapiens 24.0 23.0 4 PMID:18644344 -4.2.1.96 4a(r)-hydroxy-6(s)-methyltetrahydropterin rattus norvegicus 10.0 10.0 1 PMID:9698371 -4.2.1.96 4a(s)-hydroxy-6(r)-methyltetrahydropterin rattus norvegicus 10.0 10.0 1 PMID:9698371 -4.2.2.1 hyaluronan streptococcus pyogenes phage h4489a 4.9 4.9 1 PMID:12071858 -4.2.2.1 hyaluronate thermasporomyces composti 17.82 17.82 1 PMID:33038404 -4.2.2.1 hyaluronic acid streptococcus equi subsp. equi 4047 7.61 7.61 1 PMID:19202092 -4.2.2.1 hyaluronic acid streptococcus pyogenes phage h4489a 5.65 5.65 1 PMID:24721581 -4.2.2.10 citrus pectin aspergillus flavus 66.0 66.0 1 PMID:24455866 -4.2.2.10 citrus pectin aspergillus terricola 110.0 110.0 1 PMID:19089648 -4.2.2.10 citrus pectin fusarium lateritium 83.3 83.3 1 * -4.2.2.10 pectin aspergillus flavus 52.2 52.2 1 * -4.2.2.10 pectin aspergillus terricola 110.0 110.0 1 PMID:19089648 -4.2.2.10 pectin penicillium citrinum 76.0 76.0 1 PMID:19747102 -4.2.2.10 pectin pseudomonas marginalis 0.83 0.83 1 PMID:12630908 -4.2.2.10 pectin 26% methylated aspergillus japonicus 20.0 20.0 1 PMID:12882638 -4.2.2.10 pectin 65% methylated aspergillus japonicus 77.0 77.0 1 PMID:12882638 -4.2.2.10 pectin 89% methylated aspergillus japonicus 86.0 86.0 1 PMID:12882638 -4.2.2.11 acetylated alginate pseudomonas aeruginosa 1.2 1.2 1 PMID:23215237 -4.2.2.11 acetylated poly-(beta-(1->4)-d-mannuronan) pseudomonas aeruginosa 1.5 1.5 1 PMID:23215237 -4.2.2.11 alginate flammeovirga sp. nj-04 3.86 3.86 1 PMID:28942564 -4.2.2.11 alginate flavobacterium sp. 999.0 999.0 1 PMID:23111633 -4.2.2.11 alginate isoptericola halotolerans 45.9 45.9 1 PMID:30065151 -4.2.2.11 alginate microbulbifer sp. alw1 69.4 69.4 1 PMID:26686613 -4.2.2.11 alginate persicobacter sp. ccb-qb2 32.2 10.4 3 PMID:29057942 -4.2.2.11 alginate pseudomonas aeruginosa 32.0 32.0 1 PMID:23215237 -4.2.2.11 alginate vibrio sp. nj-04 59.0 59.0 1 PMID:29698759 -4.2.2.11 alginate vibrio splendidus 7.1 5.8 2 PMID:25556193 -4.2.2.11 alginate wenyingzhuangia fucanilytica 27.94 27.94 1 PMID:302448453 -4.2.2.11 poly(alpha-(1,4)-l-guluronate) flammeovirga sp. nj-04 3.37 3.37 1 PMID:28942564 -4.2.2.11 poly(alpha-(1,4)-l-guluronate) isoptericola halotolerans 24.8 24.8 1 PMID:30065151 -4.2.2.11 poly(alpha-(1,4)-l-guluronate) vibrio sp. nj-04 29.0 29.0 1 PMID:29698759 -4.2.2.11 poly(alpha-(1->4)-l-guluronate) vibrio sp. nju-03 45.87 45.87 1 PMID:29107140 -4.2.2.11 poly(alpha-(1->4)-l-guluronic acid) flammeovirga sp. nj-04 3.33 3.33 1 PMID:30647773 -4.2.2.11 poly(alpha-(1->4)-l-guluronic acid) marinimicrobium sp. h1 162.1 155.7 3 PMID:31547564 -4.2.2.11 poly(alpha-(1->4)-l-guluronic acid) microbulbifer sp. by17 16.68 16.68 1 PMID:35137421 -4.2.2.11 poly(beta-(1,4)-d-mannuronate) flammeovirga sp. nj-04 2.52 2.52 1 PMID:28942564 -4.2.2.11 poly(beta-(1,4)-d-mannuronate) isoptericola halotolerans 26.9 26.9 1 PMID:30065151 -4.2.2.11 poly(beta-(1,4)-d-mannuronate) vibrio sp. nj-04 77.0 77.0 1 PMID:29698759 -4.2.2.11 poly(beta-(1->4)-d-mannuronate) vibrio sp. nju-03 5.5 5.5 1 PMID:29107140 -4.2.2.11 poly(beta-(1->4)-d-mannuronic acid) flammeovirga sp. nj-04 1.48 1.48 1 PMID:30647773 -4.2.2.11 poly(beta-(1->4)-d-mannuronic acid) marinimicrobium sp. h1 66.8 62.3 3 PMID:31547564 -4.2.2.11 poly(beta-(1->4)-d-mannuronic acid) microbulbifer sp. by17 6.55 6.55 1 PMID:35137421 -4.2.2.11 poly(beta-(1->4)-d-mannuronic acid/alpha-(1->4)-l-guluronic acid) flammeovirga sp. nj-04 2.73 2.73 1 PMID:30647773 -4.2.2.11 poly-(beta-(1->4)-d-mannuronan) pseudomonas aeruginosa 32.0 32.0 1 PMID:23215237 -4.2.2.11 sodium alginate flammeovirga sp. nj-04 2.22 2.22 1 PMID:30647773 -4.2.2.11 sodium alginate flavobacterium sp. 872.8 872.8 1 PMID:23111633 -4.2.2.11 sodium alginate marinimicrobium sp. h1 262.6 260.5 3 PMID:31547564 -4.2.2.11 sodium alginate microbulbifer sp. by17 13.85 13.85 1 PMID:35137421 -4.2.2.11 sodium alginate pseudoalteromonas carrageenovora 2185.0 1875.0 5 PMID:32023889 -4.2.2.11 sodium alginate saccharophagus degradans 56.9 28.4785 2 PMID:24478312 -4.2.2.11 sodium alginate vibrio sp. nju-03 30.64 30.64 1 PMID:29107140 -4.2.2.11 sodium alginate vibrio xiamenensis 15960.0 5523.81 3 PMID:35563187 -4.2.2.11 sodium alginate zobellia galactanivorans 19.51 17.89 3 PMID:23782694 -4.2.2.12 xanthan bacillus sp. (in: firmicutes) 2170.0 2170.0 1 PMID:15979090 -4.2.2.12 xanthan bacillus sp. gl1 6120.0 2170.0 3 PMID:17223699 -4.2.2.12 xanthan microbacterium sp. xt11 0.0042 0.0036 2 * -4.2.2.13 2,4,6-trichlorophenyl alpha-d-glucopyranoside gracilariopsis sp. 1.0 1.0 1 PMID:14596624 -4.2.2.13 2,4-dinitrophenyl alpha-d-glucopyranoside gracilariopsis sp. 27.0 27.0 1 PMID:14596624 -4.2.2.13 2,5-dinitrophenyl alpha-d-glucopyranoside gracilariopsis sp. 11.0 11.0 1 PMID:14596624 -4.2.2.13 2-nitrophenyl alpha-d-glucopyranoside gracilariopsis sp. 5.3 5.3 1 PMID:14596624 -4.2.2.13 3,4-dinitrophenyl alpha-d-glucopyranoside gracilariopsis sp. 1.7 1.7 1 PMID:14596624 -4.2.2.13 3,5-dichlorophenyl alpha-d-glucopyranoside gracilariopsis sp. 1.5 1.5 1 PMID:14596624 -4.2.2.13 3-nitrophenyl alpha-d-glucopyranoside gracilariopsis sp. 6.08 3.37 2 PMID:14596624 -4.2.2.13 4-chloro-2-nitrophenyl alpha-d-glucopyranoside gracilariopsis sp. 6.3 6.3 1 PMID:14596624 -4.2.2.13 4-chlorophenyl alpha-d-glucopyranoside gracilariopsis sp. 0.44 0.44 1 PMID:14596624 -4.2.2.13 4-nitrophenyl alpha-d-glucopyranoside gracilariopsis sp. 0.4 0.4 1 PMID:14596624 -4.2.2.13 5-fluoro-alpha-d-glucopyranosyl fluoride gracilariopsis sp. 0.131 0.131 1 PMID:14596624 -4.2.2.13 alpha-d-glucopyranosyl fluoride gracilariopsis sp. 505.0 505.0 1 PMID:14596624 -4.2.2.13 p-nitrophenyl alpha-d-glucopyranoside gracilariopsis sp. 0.38 0.38 1 PMID:11982345 -4.2.2.13 phenyl alpha-d-glucopyranoside gracilariopsis sp. 0.11 0.11 1 PMID:14596624 -4.2.2.14 deacetylated glucuronan trichoderma harzianum 0.00838 0.00781 4 PMID:33049934 -4.2.2.14 glucuronan trichoderma parareesei 50.4 5.6 3 PMID:34705548 -4.2.2.18 inulin paenarthrobacter aurescens 1437.0 1285.5 4 PMID:25565432 -4.2.2.19 dermatan sulfate pedobacter heparinus 410.0 200.0 4 PMID:11500043;PMID:12063249;PMID:15155751 -4.2.2.2 67% esterified citrus pectin cellvibrio japonicus 265.0 265.0 1 PMID:11256960 -4.2.2.2 89% esterified citrus pectin cellvibrio japonicus 22.0 22.0 1 PMID:11256960 -4.2.2.2 apple pectin aspergillus luchuensis var. saitoi 642.0 642.0 1 PMID:30409626 -4.2.2.2 apple pectin aspergillus nidulans 357.0 357.0 1 PMID:35802235 -4.2.2.2 apple pectin bacillus licheniformis 166.5 166.5 1 * -4.2.2.2 citrus pectin aspergillus nidulans 272.0 272.0 1 PMID:35802235 -4.2.2.2 citrus pectin bacillus licheniformis 142.3 142.3 1 * -4.2.2.2 citrus peel pectin aspergillus luchuensis var. saitoi 694.0 694.0 1 PMID:30409626 -4.2.2.2 digalacturonic acid fusarium verticillioides 6.6 6.6 1 PMID:16697174 -4.2.2.2 homogalacturonan aspergillus nidulans 280.0 280.0 1 PMID:35802235 -4.2.2.2 pectin caldicellulosiruptor bescii 2132.7 1129.85 2 PMID:32532871 -4.2.2.2 pectin fusarium verticillioides 110.6 65.8 2 PMID:16697174 -4.2.2.2 pectin uncultured bacterium 1882.0 1316.0 2 * -4.2.2.2 polygalacturonate aspergillus luchuensis var. saitoi 601.0 601.0 1 PMID:30409626 -4.2.2.2 polygalacturonate bacillus licheniformis 193.8 193.8 1 * -4.2.2.2 polygalacturonate bacillus sp. rn1 116.1 116.1 1 PMID:32850721 -4.2.2.2 polygalacturonate bacillus subtilis 2300.0 1200.0 3 PMID:20000851;PMID:28975516 -4.2.2.2 polygalacturonate fusarium verticillioides 131.5 131.5 1 PMID:16697174 -4.2.2.2 polygalacturonate paenibacillus polymyxa 202.3 202.3 1 PMID:30373112 -4.2.2.2 polygalacturonic acid bacillus sp. (in: firmicutes) 173.0 173.0 1 PMID:10759850 -4.2.2.2 polygalacturonic acid bacillus sp. n16-5 3319.0 3319.0 1 PMID:26070675 -4.2.2.2 polygalacturonic acid cellvibrio japonicus 260.0 259.75 2 PMID:11256960 -4.2.2.2 polygalacturonic acid massilia eurypsychrophila 40.7 40.7 1 PMID:31028436 -4.2.2.2 polygalacturonic acid uncultured bacterium 6092.0 4193.5 2 * -4.2.2.2 rhamnogalacturonan-i aspergillus nidulans 236.0 236.0 1 PMID:35802235 -4.2.2.2 tetragalacturonate bacillus subtilis 1000.0 1000.0 1 PMID:20000851 -4.2.2.2 trigalacturonate bacillus subtilis 340.0 340.0 1 PMID:20000851 -4.2.2.2 trigalacturonic acid fusarium verticillioides 65.95 65.95 1 PMID:16697174 -4.2.2.20 chondroitin 4-sulfate proteus vulgaris 84.8 78.8 5 PMID:22274395;PMID:23159774 -4.2.2.20 chondroitin 6-sulfate proteus vulgaris 100.0 100.0 1 PMID:22274395 -4.2.2.20 chondroitin sulfate a proteus vulgaris 587.0 587.0 1 PMID:25077839 -4.2.2.20 dermatan sulfate proteus vulgaris 48.5 48.5 1 PMID:22274395 -4.2.2.21 chondroitin 4-sulfate proteus vulgaris 867.0 441.835 2 PMID:15691229;PMID:18849565 -4.2.2.21 chondroitin 6-sulfate proteus vulgaris 617.0 617.0 3 PMID:15691229;PMID:16108757;PMID:18849565 -4.2.2.21 chondroitin sulfate a bacteroides thetaiotaomicron 263.2 263.2 1 PMID:18227125;PMID:18512954 -4.2.2.21 chondroitin sulfate a vibrio hyugaensis 88.5 88.5 1 PMID:34356824 -4.2.2.21 chondroitin sulfate b vibrio hyugaensis 74.47 74.47 1 PMID:34356824 -4.2.2.21 chondroitin sulfate c bacteroides thetaiotaomicron 173.0 173.0 1 PMID:18227125;PMID:18512954 -4.2.2.21 chondroitin sulfate c vibrio hyugaensis 57.75 57.75 1 PMID:34356824 -4.2.2.21 dermatan sulfate bacteroides thetaiotaomicron 38.45 38.45 1 PMID:18227125;PMID:18512954 -4.2.2.21 dermatan sulfate proteus vulgaris 450.0 450.0 3 PMID:15691229;PMID:16108757;PMID:18849565 -4.2.2.23 pectic galactan acetivibrio thermocellus 7.7 7.7 1 PMID:26921189 -4.2.2.23 pectin acetivibrio thermocellus 9.8 9.8 1 PMID:26921189 -4.2.2.23 potato galactan acetivibrio thermocellus 6.4 6.4 1 PMID:26921189 -4.2.2.23 potato pectic galactan ruminiclostridium cellulolyticum 34.0 34.0 1 PMID:12896991 -4.2.2.23 potato rhamnogalacturonan i acetivibrio thermocellus 21.0 21.0 1 PMID:26921189 -4.2.2.23 soybean rhamnogalacturonan i acetivibrio thermocellus 21.2 21.2 1 PMID:26921189 -4.2.2.26 alginate stenotrophomonas maltophilia 34.8 34.8 1 PMID:26913076 -4.2.2.26 di(beta-(1->4)-d-mannuronate) zobellia galactanivorans 13.4 13.4 1 PMID:34184062 -4.2.2.26 hexa(beta-(1->4)-d-mannuronate) zobellia galactanivorans 43.1 43.1 1 PMID:34184062 -4.2.2.26 penta(beta-(1->4)-d-mannuronate) zobellia galactanivorans 38.6 38.6 1 PMID:34184062 -4.2.2.26 poly(beta-(1,4)-d-mannuronate) stenotrophomonas maltophilia 62.2 62.2 1 PMID:26913076 -4.2.2.26 poly(beta-(1,4)-d-mannuronic acid/alpha-(1,4)-l-guluronic acid) stenotrophomonas maltophilia 22.2 22.2 1 PMID:26913076 -4.2.2.26 poly(beta-(1,4)glucuronate) stenotrophomonas maltophilia 0.4 0.4 1 PMID:26913076 -4.2.2.26 poly(beta-(1,4)guluronate) stenotrophomonas maltophilia 34.6 34.6 1 PMID:26913076 -4.2.2.26 poly(beta-(1->4)-d-mannuronate) zobellia galactanivorans 39.5 39.5 1 PMID:34184062 -4.2.2.26 sodium alginate zobellia galactanivorans 4.7 4.7 1 PMID:34184062 -4.2.2.26 tetra(beta-(1->4)-d-mannuronate) zobellia galactanivorans 38.3 38.3 1 PMID:34184062 -4.2.2.26 tri(beta-(1->4)-d-mannuronate) zobellia galactanivorans 44.5 44.5 1 PMID:34184062 -4.2.2.28 gum arabic fusarium oxysporum 39.6 39.6 1 PMID:34303708 -4.2.2.28 gum arabic degraded by gh79 4-o-alpha-l-rhamnosyl-beta-d-glucuronidase fusarium oxysporum 63.4 63.4 1 PMID:34303708 -4.2.2.29 insoluble peptidoglycan pseudomonas aeruginosa 0.45 0.45 1 PMID:16475802 -4.2.2.3 alginate bacillus weihaiensis 911.7 911.7 1 PMID:32745554 -4.2.2.3 alginate bacteroides cellulosilyticus 5.4 5.4 2 PMID:31530640;PMID:32745554 -4.2.2.3 alginate defluviitalea phaphyphila 391.0 386.5 2 PMID:29292503 -4.2.2.3 alginate flammeovirga sp. nj-04 3.86 3.86 1 PMID:28942564 -4.2.2.3 alginate isoptericola halotolerans 45.9 45.9 1 PMID:30065151 -4.2.2.3 alginate microbulbifer sp. 6532a 42.0 42.0 1 PMID:32745554 -4.2.2.3 alginate microbulbifer sp. alw1 69.4 69.4 1 PMID:26686613 -4.2.2.3 alginate persicobacter sp. ccb-qb2 32.2 10.4 3 PMID:29057942 -4.2.2.3 alginate pseudomonas aeruginosa 748.0 375.21 2 PMID:15136569 -4.2.2.3 alginate saccharophagus degradans 0.019 0.019 1 PMID:32745554 -4.2.2.3 alginate stenotrophomonas maltophilia 34.8 34.8 1 PMID:32745554 -4.2.2.3 alginate vibrio sp. nj-04 59.0 59.0 1 PMID:29698759 -4.2.2.3 alginate vibrio splendidus 164.0 30.85 4 PMID:25556193;PMID:32745554 -4.2.2.3 alginate wenyingzhuangia fucanilytica 27.94 27.94 1 PMID:302448453 -4.2.2.3 hepta-alpha1,4-l-guluronic acid alteromonas sp. 7.6 7.6 1 PMID:11272816 -4.2.2.3 hepta-beta1,4-d-mannuronate alteromonas sp. 13.2 13.2 1 PMID:11272816 -4.2.2.3 hexa-alpha1,4-l-guluronic acid alteromonas sp. 7.9 7.9 1 PMID:11272816 -4.2.2.3 hexa-beta1,4-d-mannuronate alteromonas sp. 11.9 11.9 1 PMID:11272816 -4.2.2.3 nona-alpha1,4-l-guluronic acid alteromonas sp. 7.8 7.8 1 PMID:11272816 -4.2.2.3 nona-beta1,4-d-mannuronate alteromonas sp. 10.8 10.8 1 PMID:11272816 -4.2.2.3 octa-alpha1,4-l-guluronic acid alteromonas sp. 7.3 7.3 1 PMID:11272816 -4.2.2.3 octa-beta1,4-d-mannuronic acid alteromonas sp. 11.1 11.1 1 PMID:11272816 -4.2.2.3 penta-alpha1,4-l-guluronic acid alteromonas sp. 6.2 6.2 1 PMID:11272816 -4.2.2.3 penta-beta1,4-d-mannuronate alteromonas sp. 7.4 7.4 1 PMID:11272816 -4.2.2.3 poly(alpha-(1,4)-l-guluronate) flammeovirga sp. nj-04 3.37 3.37 1 PMID:28942564 -4.2.2.3 poly(alpha-(1,4)-l-guluronate) vibrio sp. nj-04 29.0 29.0 1 PMID:29698759 -4.2.2.3 poly(alpha-(1,4)-l-guluronic acid) isoptericola halotolerans 24.8 24.8 1 PMID:30065151 -4.2.2.3 poly(alpha-(1->4)-l-guluronic acid) flammeovirga sp. nj-04 4.98 4.98 1 PMID:31159265 -4.2.2.3 poly(alpha-(1->4)-l-guluronic acid) microbulbifer sp. 6532a 26.0 26.0 1 PMID:32745554 -4.2.2.3 poly(alpha-(1->4)-l-guluronic acid) rubrivirga marina 10.1 10.1 1 PMID:36569190 -4.2.2.3 poly(alpha-(1->4)-l-guluronic acid) stenotrophomonas maltophilia 34.6 34.6 1 PMID:32745554 -4.2.2.3 poly(alpha-(1->4)-l-guluronic acid) thalassotalea algicola 16.362 16.362 1 PMID:36005509 -4.2.2.3 poly(alpha-(1->4)-l-guluronic acid) vibrio sp. w13 34.26 34.26 1 PMID:33159942 -4.2.2.3 poly(alpha-(1->4)-l-guluronic acid) vibrio splendidus 246.0 126.4 2 PMID:32745554 -4.2.2.3 poly(beta-(1,4)-d-mannuronate) flammeovirga sp. nj-04 2.52 2.52 1 PMID:28942564 -4.2.2.3 poly(beta-(1,4)-d-mannuronate) vibrio sp. nj-04 77.0 77.0 1 PMID:29698759 -4.2.2.3 poly(beta-(1,4)-d-mannuronate/alpha-(1,4)-l-guluronate) defluviitalea phaphyphila 599.0 599.0 1 PMID:29292503 -4.2.2.3 poly(beta-(1,4)-d-mannuronic acid) isoptericola halotolerans 26.9 26.9 1 PMID:30065151 -4.2.2.3 poly(beta-(1->4)-d-mannuronic acid) bacillus weihaiensis 474.6 474.6 1 PMID:29522433;PMID:32745554 -4.2.2.3 poly(beta-(1->4)-d-mannuronic acid) bacteroides cellulosilyticus 43.4 43.4 2 PMID:31530640;PMID:32745554 -4.2.2.3 poly(beta-(1->4)-d-mannuronic acid) defluviitalea phaphyphila 184.0 184.0 1 PMID:29292503 -4.2.2.3 poly(beta-(1->4)-d-mannuronic acid) ectopseudomonas mendocina 224.0 224.0 1 PMID:36360141 -4.2.2.3 poly(beta-(1->4)-d-mannuronic acid) flammeovirga sp. nj-04 17.66 17.66 1 PMID:31159265 -4.2.2.3 poly(beta-(1->4)-d-mannuronic acid) microbulbifer sp. 6532a 46.0 46.0 1 PMID:32745554 -4.2.2.3 poly(beta-(1->4)-d-mannuronic acid) rubrivirga marina 13.54 13.54 1 PMID:36569190 -4.2.2.3 poly(beta-(1->4)-d-mannuronic acid) stenotrophomonas maltophilia 62.2 62.2 1 PMID:32745554 -4.2.2.3 poly(beta-(1->4)-d-mannuronic acid) thalassotalea algicola 13.73 13.73 1 PMID:36005509 -4.2.2.3 poly(beta-(1->4)-d-mannuronic acid) vibrio sp. w13 20.65 20.65 1 PMID:33159942 -4.2.2.3 poly(beta-(1->4)-d-mannuronic acid) vibrio splendidus 217.0 173.5 2 PMID:32745554 -4.2.2.3 poly(beta-(1->4)-d-mannuronic acid/alpha-(1->4)-l-guluronic acid) stenotrophomonas maltophilia 22.2 22.2 1 PMID:32745554 -4.2.2.3 poly(beta-(1->4)-d-mannuronic acid/alpha-(1->4)-l-guluronic acid) vibrio splendidus 432.0 243.15 2 PMID:32745554 -4.2.2.3 sodium alginate bacillus weihaiensis 911.7 911.7 1 PMID:29522433 -4.2.2.3 sodium alginate ectopseudomonas mendocina 232.0 232.0 1 PMID:36360141 -4.2.2.3 sodium alginate flammeovirga sp. nj-04 33.98 33.98 1 PMID:31159265 -4.2.2.3 sodium alginate microbulbifer sp. alw1 1638.81 1638.81 1 PMID:30926463 -4.2.2.3 sodium alginate paenibacillus sp. fpu-7 14.0 14.0 1 PMID:31619701 -4.2.2.3 sodium alginate rubrivirga marina 10.38 10.38 1 PMID:36569190 -4.2.2.3 sodium alginate saccharophagus degradans 56.9 28.4785 2 PMID:24478312 -4.2.2.3 sodium alginate thalassotalea algicola 14.305 14.305 1 PMID:36005509 -4.2.2.3 sodium alginate vibrio sp. ni1 0.433 0.433 1 PMID:35892947 -4.2.2.3 sodium alginate vibrio sp. qy102 2.88 2.88 1 PMID:30201400 -4.2.2.3 sodium alginate vibrio sp. w13 75.6 75.6 1 PMID:33159942 -4.2.2.3 sodium alginate wenyingzhuangia fucanilytica 27.94 27.94 1 PMID:302448453 -4.2.2.3 tetra-alpha1,4-l-guluronic acid alteromonas sp. 2.5 2.5 1 PMID:11272816 -4.2.2.3 tetra-beta1,4-d-mannuronate alteromonas sp. 3.2 3.2 1 PMID:11272816 -4.2.2.5 4-o-(2',4'-dinitrophenyl)-beta-d-glucopyranosiruronic acid pedobacter heparinus 0.041 0.041 1 PMID:16521140 -4.2.2.5 benzyl 4-deoxy-4-fluoro-beta-d-glucopyranosiduronic acid pedobacter heparinus 0.16 0.16 1 PMID:12234466 -4.2.2.5 benzyl 4-o-(2',4'-dinitrophenyl)-beta-d-glucopyranosiduronic acid pedobacter heparinus 0.019 0.019 1 PMID:12175234;PMID:12234466 -4.2.2.5 benzyl 4-o-(2'-nitrophenyl)-beta-d-glucopyranosiduronic acid pedobacter heparinus 0.027 0.027 1 PMID:12175234 -4.2.2.5 benzyl 4-o-(3',4'-dinitrophenyl)-beta-d-glucopyranosiduronic acid pedobacter heparinus 0.019 0.019 1 PMID:12175234 -4.2.2.5 benzyl 4-o-(4'-chloro-2'-nitrophenyl)-beta-d-glucopyranosiduronic acid pedobacter heparinus 0.035 0.035 1 PMID:12175234 -4.2.2.5 benzyl s-(2-acetamido-2-deoxy-beta-d-galactopyranosyl)-(1-4)-4-deoxy-4-thio-beta-d-glucopyranosiduronic acid pedobacter heparinus 0.005 0.005 1 PMID:15013408 -4.2.2.5 chondroitin paenarthrobacter aurescens 868.0 868.0 1 PMID:914791 -4.2.2.5 chondroitin pedobacter heparinus 840.0 840.0 1 PMID:914791 -4.2.2.5 chondroitin 4-sulfate paenarthrobacter aurescens 403.0 403.0 1 PMID:914791 -4.2.2.5 chondroitin 4-sulfate pedobacter heparinus 308.0 271.0 2 PMID:11500043;PMID:914791 -4.2.2.5 chondroitin 6-sulfate paenarthrobacter aurescens 522.0 522.0 1 PMID:914791 -4.2.2.5 chondroitin 6-sulfate pedobacter heparinus 855.0 480.0 3 PMID:11500043;PMID:16521140;PMID:914791 -4.2.2.5 hyaluronate paenarthrobacter aurescens 1200.0 1200.0 1 PMID:914791 -4.2.2.5 hyaluronate pedobacter heparinus 570.0 570.0 1 PMID:914791 -4.2.2.5 phenyl 4-deoxy-4-fluoro-beta-d-glucopyranosiduronic acid pedobacter heparinus 2.3 2.3 1 PMID:12234466 -4.2.2.5 phenyl 4-methylumbelliferyl-beta-d-glucopyranosiduronic acid pedobacter heparinus 0.0016 0.0015500000000000002 2 PMID:12175234;PMID:12234466 -4.2.2.7 heparin pedobacter heparinus 21.0 20.155 2 PMID:31399136 -4.2.2.7 heparin pseudopedobacter saltans 8.9 8.9 1 * -4.2.2.7 heparin, 20-mer bacteroides thetaiotaomicron 29.1 29.1 1 PMID:19801541 -4.2.2.7 heparin, 6-mer bacteroides thetaiotaomicron 78.4 78.4 1 PMID:19801541 -4.2.2.7 heparin, 8-mer bacteroides thetaiotaomicron 73.7 73.7 1 PMID:19801541 -4.2.2.8 heparan sulfate pedobacter heparinus 94.0 78.0 3 PMID:10747789;PMID:28067452 -4.2.2.8 heparin pedobacter heparinus 1.9 1.9 1 PMID:28067452 -4.2.3.1 l-vinylglycine thermus thermophilus 0.61 0.61 1 PMID:21084312 -4.2.3.1 o-phospho-l-homoserine escherichia coli 4.0 4.0 1 PMID:22289691 -4.2.3.1 o-phospho-l-homoserine methanosarcina acetivorans c2a 4080.0 4080.0 1 PMID:19761441 -4.2.3.1 o-phospho-l-homoserine mycobacterium tuberculosis 7.3 7.3 1 PMID:18621388 -4.2.3.1 o-phospho-l-homoserine thermus thermophilus 0.8 0.8 1 PMID:21084312 -4.2.3.1 o-phosphohomoserine arabidopsis thaliana 3.5 0.63 4 PMID:10429206;PMID:9748328 -4.2.3.1 o-phosphohomoserine escherichia coli 7.33 7.33 1 PMID:7907888 -4.2.3.1 phosphate thermus thermophilus 0.034 0.034 1 PMID:21084312 -4.2.3.104 (2e)-geranyl diphosphate zingiber zerumbet 3.8 3.8 1 * -4.2.3.104 (2e,6e)-farnesyl diphosphate zingiber zerumbet 5.61 5.61 3 PMID:26463657;PMID:32624945 -4.2.3.104 (2z)-neryl diphosphate zingiber zerumbet 4.26 4.26 1 * -4.2.3.106 (2e,6e)-farnesyl diphosphate arabidopsis thaliana 0.0048 0.0048 1 PMID:20463089 -4.2.3.106 geranyl diphosphate arabidopsis thaliana 0.034 0.034 1 PMID:20463089 -4.2.3.106 geranyl diphosphate camellia sinensis 0.00474 0.00474 1 PMID:34554738 -4.2.3.106 geranyl diphosphate camellia sinensis var. sinensis 0.0047 0.0047 1 PMID:34554738 -4.2.3.107 geranyl diphosphate lavandula x intermedia 2.07 2.07 1 PMID:28258552 -4.2.3.107 geranyl diphosphate picea sitchensis 2.21 1.154 2 PMID:21323772;PMID:25016016 -4.2.3.107 neryl diphosphate lavandula x intermedia 0.636 0.636 1 PMID:28258552 -4.2.3.108 geranyl diphosphate arabidopsis thaliana 0.001 0.001 1 PMID:15299125 -4.2.3.108 geranyl diphosphate artemisia annua 4.46 4.46 1 PMID:27242840 -4.2.3.108 geranyl diphosphate lavandula x intermedia 0.0088 0.0088 1 PMID:22592779 -4.2.3.108 geranyl diphosphate nicotiana suaveolens 0.00041 0.00041 1 PMID:27729471 -4.2.3.108 geranyl diphosphate salvia fruticosa 0.053 0.053 1 PMID:17557809 -4.2.3.108 geranyl diphosphate streptomyces clavuligerus 0.079 0.079 1 PMID:21726035 -4.2.3.109 geranyl diphosphate arabidopsis thaliana 0.001 0.001 1 PMID:15299125 -4.2.3.109 geranyl diphosphate picea sitchensis 0.545 0.545 1 PMID:25016016 -4.2.3.113 geranyl diphosphate picea sitchensis 0.545 0.3215 2 PMID:25016016 -4.2.3.116 geranyl diphosphate artemisia annua 1.49 1.49 1 PMID:27242840 -4.2.3.117 geranyl diphosphate artemisia annua 1.49 1.49 1 PMID:27242840 -4.2.3.118 (e)-2-methylgeranyl diphosphate streptomyces coelicolor 0.105 0.072 2 PMID:18563898;PMID:28246382 -4.2.3.118 2-methylneryl diphosphate streptomyces coelicolor 0.0046 0.0046 1 PMID:28246382 -4.2.3.118 geranyl diphosphate streptomyces coelicolor 0.0003 0.0003 1 PMID:18563898 -4.2.3.12 6-(l-erythro-1,2-dihydroxypropyl 3-triphosphate)-7,8-dihydropterin homo sapiens 0.032 0.032 1 PMID:7493990 -4.2.3.121 geranyl diphosphate lavandula angustifolia 0.012 0.012 1 PMID:17662687 -4.2.3.124 d-glucose 6-phosphate micromonospora echinospora 0.077 0.077 1 PMID:33577648 -4.2.3.124 d-glucose 6-phosphate niallia circulans 1.0 0.42 8 PMID:10344560;PMID:10470681;PMID:12224638;PMID:17035031;PMID:33577648 -4.2.3.124 d-glucose 6-phosphate rickettsia endosymbiont of ixodes scapularis 0.04 0.04 1 PMID:33577648 -4.2.3.124 d-glucose 6-phosphate streptoalloteichus hindustanus 0.075 0.057499999999999996 2 PMID:16915821;PMID:33577648 -4.2.3.124 d-glucose 6-phosphate streptomyces fradiae 0.0022 0.0022 1 PMID:33577648 -4.2.3.124 d-glucose 6-phosphate streptomyces tenjimariensis 0.058 0.058 1 PMID:33577648 -4.2.3.13 (2e,6e)-farnesyl diphosphate gossypium arboreum 0.01 0.00127 5 PMID:27431578;PMID:29115742 -4.2.3.13 (2e,6e)-farnesyl diphosphate phyla dulcis 0.04 0.04 1 PMID:22867794 -4.2.3.13 (2e,6e)-farnesyl diphosphate piper nigrum 0.694 0.694 1 PMID:29248443 -4.2.3.13 (2e,6z)-farnesyl diphosphate gossypium arboreum 0.01 0.01 1 PMID:19489610 -4.2.3.13 2-trans,6-trans-farnesyl diphosphate gossypium arboreum 0.033 0.033 1 PMID:8554317 -4.2.3.132 (+)-copalyl diphosphate abies grandis 2.6 1.675 2 PMID:11112547;PMID:22219188 -4.2.3.133 (2e,6e)-farnesyl diphosphate phyla dulcis 0.04 0.04 1 PMID:22867794 -4.2.3.133 (2e,6e)-farnesyl diphosphate piper nigrum 0.185 0.185 1 PMID:29248443 -4.2.3.135 (2e,6e)-farnesyl diphosphate stereum hirsutum 0.0063 0.0044 3 PMID:24166732 -4.2.3.138 (2e,6e)-farnesyl diphosphate phyla dulcis 0.04 0.04 2 PMID:22867794 -4.2.3.139 (2e,6e)-farnesyl diphosphate valeriana officinalis 0.018 0.013999999999999999 2 PMID:22776156;PMID:34898176 -4.2.3.141 (13e)-8alpha-hydroxylabd-13-en-15-yl diphosphate salvia sclarea 0.53 0.53 1 PMID:29713562 -4.2.3.142 (2z,6z)-farnesyl diphosphate solanum habrochaites 0.29 0.29 1 PMID:23169639 -4.2.3.143 (2e,6e)-farnesyl diphosphate elaeoselinum garganicum 0.29 0.15999999999999998 2 PMID:22938155;PMID:27721652 -4.2.3.144 (2e,6e)-farnesyl diphosphate solanum lycopersicum 0.43 0.43 1 PMID:25052853 -4.2.3.144 geranylgeranyl diphosphate nicotiana attenuata 7.53 7.53 1 PMID:25052853 -4.2.3.144 geranylgeranyl diphosphate solanum lycopersicum 6.85 6.85 1 PMID:25052853 -4.2.3.148 geranylgeranyl diphosphate streptomyces sp. 0.047 0.047 1 PMID:23386483 -4.2.3.149 geranylgeranyl diphosphate streptomyces sp. 0.047 0.0345 2 PMID:23386483 -4.2.3.15 geranyl diphosphate artemisia annua 0.52 0.52 1 PMID:27242840 -4.2.3.150 geranylgeranyl diphosphate streptomyces sp. 0.022 0.022 1 PMID:23386483 -4.2.3.151 geranylgeranyl diphosphate streptomyces sp. 0.022 0.022 1 PMID:23386483 -4.2.3.153 d-glyceraldehyde 3-phosphate methanocaldococcus jannaschii 0.026 0.026 1 PMID:25905665 -4.2.3.154 d-sedoheptulose 7-phosphate nostoc punctiforme 0.0833 0.0833 1 PMID:22741921 -4.2.3.154 d-sedoheptulose 7-phosphate trichormus variabilis 0.0533 0.0533 1 PMID:22741921 -4.2.3.155 d-sedoheptulose 7-phosphate actinosynnema mirum 0.033 0.033 1 PMID:22741921 -4.2.3.155 d-sedoheptulose 7-phosphate stigmatella aurantiaca 0.062 0.062 1 PMID:22741921 -4.2.3.158 geranylgeranyl diphosphate streptomyces sp. cwa1 0.0059 0.0059 1 PMID:33496585 -4.2.3.158 geranylgeranyl diphosphate streptomyces violens 0.0065 0.00355 4 PMID:30369053 -4.2.3.167 geranylgeranyl diphosphate arabidopsis thaliana 0.83 0.83 1 PMID:27933080 -4.2.3.168 geranylgeranyl diphosphate arabidopsis thaliana 0.83 0.83 1 PMID:27933080 -4.2.3.17 geranylgeranyl diphosphate taxus brevifolia 0.16 0.00017 7 PMID:10864451;PMID:25257933;PMID:28362483 -4.2.3.173 (2e,6e)-farnesyl diphosphate zea mays 0.0014 0.0014 1 PMID:27421723 -4.2.3.18 copalyl diphosphate abies grandis 0.75 0.75 1 PMID:11112547 -4.2.3.19 ent-copalyl diphosphate arabidopsis thaliana 1.3 1.3 1 PMID:33524857 -4.2.3.194 (2e,6e)-farnesyl diphosphate aquimarina spongiae 0.086 0.086 1 PMID:35446557 -4.2.3.194 (2e,6e)-farnesyl diphosphate valeriana officinalis 0.025 0.025 1 PMID:25447532 -4.2.3.199 (2e,6e)-farnesyl-diphosphate salvia miltiorrhiza 2.09 2.07 3 PMID:28487717 -4.2.3.2 ethanolamine phosphate homo sapiens 2.3 1.2 3 PMID:25327712 -4.2.3.20 2-fluorogeranyl diphosphate citrus sinensis 0.00054 0.00054 1 PMID:28272876 -4.2.3.20 2-fluoroneryl diphosphate citrus sinensis 0.00024 0.00024 1 PMID:28272876 -4.2.3.20 geranyl diphosphate citrus sinensis 0.186 0.186 1 PMID:28272875 -4.2.3.20 geranyl diphosphate lavandula angustifolia 0.012 0.012 1 PMID:17662687 -4.2.3.21 trans,trans-farnesyl diphosphate hyoscyamus muticus 0.04 0.04 1 PMID:9204881 -4.2.3.212 (2e,6e)-farnesyl diphosphate coniophora puteana 0.0324 0.0324 1 PMID:35440053 -4.2.3.22 (2e,6e)-farnesyl diphosphate streptomyces coelicolor 0.0062 0.0062 1 PMID:17873868 -4.2.3.22 2-trans,6-trans-farnesyl diphosphate streptomyces coelicolor 6.2 4.7 2 PMID:12556563 -4.2.3.22 farnesyl diphosphate streptomyces avermitilis 0.0031 0.0031 1 PMID:17080683 -4.2.3.226 (2z,6e)-farnesyl diphosphate nicotiana tabacum 0.095 0.095 2 PMID:20175559;PMID:20201526 -4.2.3.227 (2z,6e)-farnesyl diphosphate nicotiana tabacum 0.095 0.095 2 PMID:20175559;PMID:20201526 -4.2.3.23 (2e,6e)-farnesyl diphosphate barnadesia spinosa 0.28 0.20500000000000002 2 PMID:27697527 -4.2.3.23 2-trans,6-trans-farnesyl diphosphate ixeridium dentatum 0.016 0.016 1 PMID:15834787 -4.2.3.23 2-trans,6-trans-farnesyl diphosphate nostoc sp. 4.4 4.4 1 PMID:18658271 -4.2.3.230 d-mannose 6-phosphate sporocytophaga myxococcoides 0.0163 0.0163 1 PMID:39404639 -4.2.3.24 (2e,6e)-farnesyl diphosphate artemisia annua 0.186 0.0108 9 PMID:15797234;PMID:27933789;PMID:28526743 -4.2.3.24 geranyl diphosphate artemisia annua 0.0007 0.0005200000000000001 2 PMID:15797234 -4.2.3.25 geranyl diphosphate actinidia arguta 0.044 0.044 1 * -4.2.3.25 geranyl diphosphate actinidia polygama 0.014 0.014 1 * -4.2.3.25 geranyl diphosphate camellia sinensis var. sinensis 0.022 0.019 2 PMID:32829629 -4.2.3.25 geranyl diphosphate coleus amboinicus 0.16 0.16 2 PMID:34429465 -4.2.3.25 geranyl diphosphate santalum album 0.197 0.197 1 PMID:33383368 -4.2.3.26 geranyl diphosphate agrocybe pediades 0.1 0.1 1 PMID:33597725 -4.2.3.26 geranyl diphosphate camellia sinensis var. sinensis 7.31e-05 5.835e-05 2 PMID:32829629 -4.2.3.26 geranyl diphosphate cyclocybe aegerita 0.0083 0.0083 1 PMID:33597725 -4.2.3.26 geranyl diphosphate mentha aquatica var. citrata 0.24 0.24 1 PMID:12176064 -4.2.3.27 dimethylallyl diphosphate bauhinia variegata 0.08 0.08 1 PMID:36367585 -4.2.3.27 dimethylallyl diphosphate calophyllum inophyllum 0.33 0.33 1 PMID:36367585 -4.2.3.27 dimethylallyl diphosphate garcinia subelliptica 0.164 0.164 1 PMID:36367585 -4.2.3.27 dimethylallyl diphosphate ipomoea batatas 0.37 0.37 1 PMID:30190176 -4.2.3.27 dimethylallyl diphosphate mangifera indica 0.256 0.256 1 PMID:36367585 -4.2.3.27 dimethylallyl diphosphate metrosideros polymorpha 0.35 0.35 1 PMID:29902970 -4.2.3.27 dimethylallyl diphosphate populus alba 0.011 0.011 1 PMID:30190176 -4.2.3.27 dimethylallyl diphosphate populus tremuloides 1.7 1.7 1 PMID:7768893 -4.2.3.27 dimethylallyl diphosphate populus trichocarpa 1.9 1.9 1 PMID:17996012 -4.2.3.27 dimethylallyl diphosphate robinia pseudoacacia 0.018 0.018 1 PMID:36367585 -4.2.3.27 dimethylallyl diphosphate syzygium cumini 1.0 1.0 1 PMID:36367585 -4.2.3.27 dimethylallyl diphosphate syzygium samarangense 0.031 0.031 1 PMID:36367585 -4.2.3.29 ent-copalyl diphosphate oryza sativa 0.00033 0.00033 1 PMID:21323642 -4.2.3.3 dihydroxyacetone phosphate escherichia coli 220.0 199.5 4 PMID:15049687;PMID:9665712 -4.2.3.3 dihydroxyacetone phosphate thermus sp. 327.0 231.5 8 PMID:23038673;PMID:23261063;PMID:23592737;PMID:24057302 -4.2.3.3 glycerone phosphate thermus sp. gh5 325.0 271.5 2 PMID:20419481;PMID:27608544 -4.2.3.31 ent-copalyl diphosphate streptomyces sp. 0.0014 0.0014 1 PMID:17148547 -4.2.3.37 (2e,6e)-farnesyl diphosphate streptomyces avermitilis 0.00026 0.00026 1 PMID:21342464 -4.2.3.37 (2e,6e)-farnesyl diphosphate streptomyces coelicolor 0.049 0.047 2 PMID:16669656;PMID:20131801 -4.2.3.38 (2e,6e)-farnesyl diphosphate abies grandis 0.002 0.002 1 PMID:22153510 -4.2.3.38 (2e,6e)-farnesyl diphosphate ginkgo biloba 0.01 0.01 2 PMID:26442918 -4.2.3.38 (2e,6e)-farnesyl diphosphate santalum album 0.0067 0.0067 1 PMID:25976282 -4.2.3.39 (2e,6e)-farnesyl diphosphate artemisia annua 0.95 0.95 1 PMID:32625036 -4.2.3.39 dimethylallyl diphosphate artemisia annua 1.88 1.64 2 PMID:32625036 -4.2.3.39 isopentenyl diphosphate artemisia annua 1.88 1.64 2 PMID:32625036 -4.2.3.4 (3r)-3-fluoro-3-deoxy-d-arabino-heptulosonate 7-phosphate actinidia chinensis 0.3 0.3 1 PMID:21387027 -4.2.3.4 (3r)-3-fluoro-3-deoxy-d-arabino-heptulosonate 7-phosphate escherichia coli 2.5 2.5 1 PMID:21387027 -4.2.3.4 (3r)-3-fluoro-3-deoxy-d-arabino-heptulosonate 7-phosphate pyrococcus furiosus 3.3 3.3 1 PMID:21387027 -4.2.3.4 (3s)-3-fluoro-3-deoxy-d-arabino-heptulosonate 7-phosphate actinidia chinensis 0.9 0.9 1 PMID:21387027 -4.2.3.4 (3s)-3-fluoro-3-deoxy-d-arabino-heptulosonate 7-phosphate escherichia coli 0.3 0.3 1 PMID:21387027 -4.2.3.4 (3s)-3-fluoro-3-deoxy-d-arabino-heptulosonate 7-phosphate pyrococcus furiosus 1.3 1.3 1 PMID:21387027 -4.2.3.4 3-deoxy-d-arabino-hept-2-ulosonate 7-phosphate actinidia chinensis 20.1 10.3 2 PMID:21387027;PMID:23916589 -4.2.3.4 3-deoxy-d-arabino-hept-2-ulosonate 7-phosphate escherichia coli 25000.0 12508.0 2 PMID:21387027;PMID:2514789 -4.2.3.4 3-deoxy-d-arabino-hept-2-ulosonate 7-phosphate pyrococcus furiosus 3.0 3.0 2 PMID:21387027;PMID:21603259 -4.2.3.4 3-deoxy-d-arabino-heptulosonate 7-phosphate aspergillus nidulans 6.8 6.8 1 PMID:15273308 -4.2.3.4 3-deoxy-d-arabino-heptulosonic acid 7-phosphate neurospora crassa 19.0 19.0 1 PMID:3157372 -4.2.3.4 7-phospho-2-dehydro-3-deoxy-d-arabino-heptonate providencia alcalifaciens 1.5 1.5 1 PMID:32661075 -4.2.3.41 farnesyl diphosphate antillogorgia elisabethae 3400.0 3400.0 1 PMID:16423548 -4.2.3.41 geranyl diphosphate antillogorgia elisabethae 1300.0 1300.0 1 PMID:16423548 -4.2.3.41 geranylgeranyl diphosphate antillogorgia elisabethae 41000.0 41000.0 1 PMID:16423548 -4.2.3.43 (2e,6e)-farnesyl diphosphate diaporthe amygdali 0.027 0.027 1 PMID:26734760 -4.2.3.43 geranyl diphosphate diaporthe amygdali 0.036 0.036 1 PMID:26734760 -4.2.3.43 geranylgeranyl diphosphate diaporthe amygdali 0.021 0.021 2 PMID:26734760;PMID:28362483 -4.2.3.46 (2e,6e)-farnesyl diphosphate actinidia deliciosa 0.44 0.44 1 PMID:19516075 -4.2.3.46 (2e,6e)-farnesyl diphosphate arabidopsis thaliana 0.0048 0.00465 2 PMID:20463089 -4.2.3.46 (2e,6e)-farnesyl diphosphate malus domestica 0.0553 0.0553 1 PMID:19181671 -4.2.3.46 farnesyl diphosphate malus domestica 0.0533 0.02975 2 PMID:19181671 -4.2.3.46 geranyl diphosphate actinidia deliciosa 0.03 0.03 1 PMID:19516075 -4.2.3.46 geranyl diphosphate malus domestica 0.000281 0.000281 2 PMID:19181671 -4.2.3.47 (2e,6e)-farnesyl diphosphate artemisia annua 0.0095 0.0095 1 PMID:15896363 -4.2.3.47 (2e,6e)-farnesyl diphosphate mentha x piperita 0.028 0.028 1 PMID:23214943 -4.2.3.47 (2e,6e)-farnesyl diphosphate streptomyces coelicolor 0.019 0.019 1 PMID:19858213 -4.2.3.47 (2z,6e)-2-fluorofarnesyl diphosphate mentha x piperita 0.02 0.02 1 PMID:23214943 -4.2.3.47 (3rs)-trans-nerolidyl diphosphate mentha x piperita 0.023 0.023 1 PMID:23214943 -4.2.3.48 (2e,6e)-farnesyl diphosphate actinidia chinensis 0.24 0.24 1 PMID:22162874 -4.2.3.48 (2e,6e)-farnesyl diphosphate coleus amboinicus 0.1 0.1 1 PMID:34429465 -4.2.3.48 (2e,6e)-farnesyl diphosphate santalum album 0.219 0.219 1 PMID:33383368 -4.2.3.48 geranyl diphosphate actinidia chinensis 0.13 0.08 2 PMID:22162874 -4.2.3.49 (2e,6e)-farnesyl diphosphate tripterygium wilfordii 0.371 0.371 1 PMID:28128232 -4.2.3.5 5-enolpyruvylshikimate 3-phosphate neurospora crassa 0.87 0.87 1 PMID:18279385 -4.2.3.5 nadh mycobacterium tuberculosis 0.0083 0.0083 1 PMID:18445278 -4.2.3.51 neryl diphosphate solanum lycopersicum 4.1 4.1 1 PMID:19487664 -4.2.3.52 geranyl diphosphate lavandula angustifolia 0.017 0.017 1 PMID:21165645 -4.2.3.55 (2e,6e)-farnesyl diphosphate santalum album 0.00067 0.00067 1 PMID:25976282 -4.2.3.57 (2e,6e)-farnesyl diphosphate ocimum kilimandscharicum 4.06 4.06 1 PMID:27005818 -4.2.3.57 (2e,6e)-farnesyl diphosphate piper nigrum 0.455 0.455 2 PMID:29248443 -4.2.3.57 (2e,6e)-farnesyl diphosphate vitis vinifera 0.19 0.19 1 PMID:27561253 -4.2.3.6 (2e,6e)-farnesyl diphosphate fusarium graminearum 0.16 0.16 1 PMID:28456298 -4.2.3.6 farnesyl diphosphate fusarium sporotrichioides 0.138 0.138 1 PMID:17996718 -4.2.3.61 (2e,6e)-farnesyl diphosphate nicotiana tabacum 0.095 0.048 3 PMID:20201526 -4.2.3.61 (2e,6z)-6-fluorofarnesyl diphosphate nicotiana tabacum 0.11 0.11 1 PMID:20201526 -4.2.3.64 (2e,6e)-farnesyl diphosphate streptomyces griseus 0.026 0.026 1 PMID:22872183 -4.2.3.67 (2e,6e)-farnesyl diphosphate mentha x piperita 0.18 0.18 1 PMID:16083926 -4.2.3.70 (2e,6e)-farnesyl diphosphate pogostemon cablin 0.0776 0.039015 2 PMID:16970904;PMID:31643144 -4.2.3.70 (2z,6e)-farnesyl diphosphate pogostemon cablin 0.072 0.072 1 PMID:26100386 -4.2.3.73 (2e,6e)-farnesyl diphosphate callitropsis nootkatensis 0.0032 0.0032 1 PMID:24112147 -4.2.3.74 (2e,6e)-farnesyl diphosphate botrytis cinerea 3.23 3.23 1 PMID:19035644 -4.2.3.75 (2e,6e)-farnesyl diphosphate coprinopsis cinerea 0.012 0.012 1 PMID:20419721 -4.2.3.75 (2e,6e)-farnesyl diphosphate piper nigrum 0.185 0.185 1 PMID:29248443 -4.2.3.75 (2e,6e)-farnesyl diphosphate solidago canadensis 0.03 0.03 1 PMID:15542052 -4.2.3.77 (2e,6e)-farnesyl diphosphate actinidia deliciosa 0.017 0.017 1 PMID:19516075 -4.2.3.77 (2e,6e)-farnesyl diphosphate solidago canadensis 0.04 0.03 2 PMID:15542052;PMID:22079737 -4.2.3.81 (2e,6e)-farnesyl diphosphate lavandula angustifolia 0.033 0.033 1 PMID:17662687 -4.2.3.81 (2e,6e)-farnesyl diphosphate santalum album 0.34 0.34 3 PMID:21454632;PMID:29438678 -4.2.3.81 (2e,6e)-farnesyl diphosphate santalum austrocaledonicum 0.91 0.91 2 PMID:21454632 -4.2.3.81 (2e,6e)-farnesyl diphosphate santalum spicatum 2.6 2.6 3 PMID:21454632;PMID:29438678 -4.2.3.82 (2e,6e)-farnesyl diphosphate clausena lansium 0.075 0.075 2 PMID:29438678 -4.2.3.82 (2e,6e)-farnesyl diphosphate santalum album 0.34 0.20665 4 PMID:21454632;PMID:29438678 -4.2.3.82 (2e,6e)-farnesyl diphosphate santalum austrocaledonicum 0.91 0.91 2 PMID:21454632 -4.2.3.82 (2e,6e)-farnesyl diphosphate santalum spicatum 2.6 1.3535000000000001 4 PMID:21454632;PMID:29438678 -4.2.3.83 (2e,6e)-farnesyl diphosphate santalum album 0.34 0.34 3 PMID:21454632;PMID:29438678 -4.2.3.83 (2e,6e)-farnesyl diphosphate santalum austrocaledonicum 0.91 0.91 2 PMID:21454632 -4.2.3.83 (2e,6e)-farnesyl diphosphate santalum spicatum 2.6 2.6 3 PMID:21454632;PMID:29438678 -4.2.3.87 (2e,6e)-farnesyl diphosphate pogostemon cablin 0.00043 0.00043 1 PMID:16970904 -4.2.3.89 (2e,6e)-farnesyl diphosphate ocimum kilimandscharicum 4.06 4.06 1 PMID:27005818 -4.2.3.89 (2e,6e)-farnesyl diphosphate piper nigrum 0.455 0.455 1 PMID:29248443 -4.2.3.89 (2e,6e)-farnesyl diphosphate streptomyces griseus 0.025 0.025 1 PMID:21693706 -4.2.3.89 (2e,6e)-farnesyl diphosphate vitis vinifera 0.19 0.19 1 PMID:27561253 -4.2.3.9 (2e,6e)-farnesyl diphosphate aspergillus terreus 0.027 0.027 1 PMID:27172425 -4.2.3.9 (2e,6e)-farnesyl diphosphate nicotiana tabacum 0.032 0.032 1 PMID:25897591 -4.2.3.9 (2e,6e)-farnesyl diphosphate penicillium roqueforti 0.084 0.084 3 PMID:12820883;PMID:21815676;PMID:21870004;PMID:22349314 -4.2.3.9 (2z,6e)-farnesyl diphosphate nicotiana tabacum 0.095 0.095 1 PMID:20201526 -4.2.3.9 anilinogeranyl diphosphate nicotiana tabacum 0.00012 0.00012 1 PMID:25897591 -4.2.3.9 farnesyl diphosphate penicillium roqueforti 550.0 0.55 3 PMID:16791319;PMID:18563268 -4.2.3.9 trans,trans-farnesyl diphosphate aspergillus terreus 0.0173 0.015 3 PMID:10775423;PMID:15186158 -4.2.3.9 trans,trans-farnesyl diphosphate penicillium roqueforti 0.043 0.043 3 PMID:10775423;PMID:12296728;PMID:15186158 -4.2.3.90 (2e,6e)-farnesyl diphosphate nostoc sp. 0.044 0.044 1 PMID:18658271 -4.2.3.90 (e,e)-farnesyl diphosphate nostoc punctiforme 0.063 0.063 1 PMID:18658271 -4.2.3.91 (2e,6e)-farnesyl diphosphate coprinopsis cinerea 0.012 0.012 2 PMID:20419721 -4.2.3.93 (2e,6e)-farnesyl diphosphate aquilaria crassna 0.00499 0.00499 1 PMID:20959422 -4.2.3.95 (2e,6e)-farnesyl diphosphate coprinopsis cinerea 0.67 0.67 2 PMID:20419721 -4.2.3.96 (2e,6e)-farnesyl diphosphate streptomyces avermitilis 0.04 0.04 1 PMID:20536237 -4.2.3.97 (2e,6e)-farnesyl diphosphate streptomyces clavuligerus 0.00114 0.00114 2 PMID:21276937 -4.2.3.98 (2e,6e)-farnesyl diphosphate streptomyces clavuligerus 0.00163 0.00163 2 PMID:21276937 -4.2.3.99 syn-copalyl diphosphate oryza sativa 0.00083 0.00083 1 PMID:21323642 -4.2.99.18 12-mer oligodeoxyribonucleotide containing a natural ap site homo sapiens 2.8 2.8 1 PMID:20575528 -4.2.99.18 12-mer oligodeoxyribonucleotide containing a tetrahydrofuran analogue at the natural ap site homo sapiens 1.0 1.0 1 PMID:20575528 -4.2.99.18 18-mer containing p33-labeled tetrahydrofuran cricetulus griseus 5.7 3.14 2 PMID:20955519 -4.2.99.18 3'-fluorescein-labeled 5'-aacttcgtgcaggcatggtag(du)ttgtctact-3' homo sapiens 0.0005 0.0005 1 PMID:28290676 -4.2.99.18 30mer thf-t duplex helicobacter pylori 0.308 0.308 1 PMID:30110394 -4.2.99.18 34fdna homo sapiens 26500.0 26500.0 1 PMID:18439621 -4.2.99.18 34frna homo sapiens 438.0 438.0 1 PMID:18439621 -4.2.99.18 35 base pair oligonucleotide containing 5,6-dihydrouracil opposite a escherichia coli 0.03 0.03 1 PMID:16096281 -4.2.99.18 35 base pair oligonucleotide containing 5,6-dihydrouracil opposite g escherichia coli 0.043 0.043 1 PMID:16096281 -4.2.99.18 35 base pair oligonucleotide containing 5,6-dihydroxy-5,6-dihydrothymine opposite a escherichia coli 0.098 0.098 1 PMID:16096281 -4.2.99.18 35 base pair oligonucleotide containing 5,6-dihydroxy-5,6-dihydrothymine opposite g escherichia coli 0.075 0.075 1 PMID:16096281 -4.2.99.18 37mer with ap/a saccharomyces cerevisiae 0.00512 0.0029100000000000003 2 PMID:14500818 -4.2.99.18 37mer with ap/c saccharomyces cerevisiae 0.0225 0.01875 2 PMID:14500818 -4.2.99.18 37mer with ap/g saccharomyces cerevisiae 0.00323 0.002155 2 PMID:14500818 -4.2.99.18 37mer with ap/t saccharomyces cerevisiae 0.0233 0.01515 2 PMID:14500818 -4.2.99.18 37mer with dihydrouridine saccharomyces cerevisiae 0.0717 0.040015 2 PMID:9558341 -4.2.99.18 4-hydroxy-5-n-methylformamidopyrimidine/c escherichia coli 0.00417 0.00417 1 PMID:14576322 -4.2.99.18 4-hydroxy-5-n-methylformamidopyrimidine/c saccharomyces cerevisiae 0.00567 0.00567 1 PMID:14576322 -4.2.99.18 43-mer oligonucleotide containing the ap-site analog thf at nt 31 homo sapiens 3.36 3.36 1 PMID:18436236 -4.2.99.18 5'-ctctcccttc-5,6-dihydrouracil-ctcctttcctct-3' escherichia coli 0.07167 0.005667 4 PMID:17002303 -4.2.99.18 5'-ctctcccttc-8-oxo-7,8-dihydroguanine-ctcctttcctct-3' escherichia coli 0.023 0.014499999999999999 4 PMID:17002303 -4.2.99.18 5'-cy3-caaggtagtruatccttg-1-black hole quencher1-3' homo sapiens 0.0272 0.0272 1 PMID:19932678 -4.2.99.18 5'-cy3-caaggtagtruatccttg-1-black hole quencher1-3' rattus norvegicus 0.168 0.168 1 PMID:19932678 -4.2.99.18 5'-gacaagcgcag-(5r,6s)-2'-deoxy-5,6-dihydroxyuridine-cagccgaacac-3' escherichia coli 0.0483 0.038335 4 PMID:17002303 -4.2.99.18 5'-gacaagcgcag-(5s,6r)-2'-deoxy-5,6-dihydroxyuridine-cagccgaacac-3' escherichia coli 0.0567 0.01725 4 PMID:17002303 -4.2.99.18 5'-tcgaggatcctgagctcgagtcgacgxtcgcgaattctgcggatccaagc-3' homo sapiens 3.2 3.2 1 PMID:22042551 -4.2.99.18 5'-tcgaggatcctgagctcgagtcgacgxtcgcgaattctgcggatccaagc-3' mus musculus 4.2 4.2 1 PMID:22042551 -4.2.99.18 8-oxodg-containing hairpin oligodeoxyribonucleotide homo sapiens 0.009 0.0075 2 PMID:36038587 -4.2.99.18 ap-dna escherichia coli 90.0 90.0 1 PMID:18408731 -4.2.99.18 ap-dna-dna homo sapiens 174.0 174.0 1 PMID:18439621 -4.2.99.18 ap-dna-rna homo sapiens 54.0 54.0 1 PMID:18439621 -4.2.99.18 dna homo sapiens 2340.0 2340.0 1 PMID:19181704 -4.2.99.18 dna leishmania major 10440.0 10440.0 1 PMID:19181704 -4.2.99.18 dna containing 2,6-diamino-4-hydroxy-5-n-methylformamidopyrimidine/c escherichia coli 0.0158 0.0158 1 PMID:14576322 -4.2.99.18 dna containing 2,6-diamino-4-hydroxy-5-n-methylformamidopyrimidine/c saccharomyces cerevisiae 0.0117 0.0117 1 PMID:14576322 -4.2.99.18 dna containing 5,6-dihydrothymidine/a saccharomyces cerevisiae 0.00333 0.00333 1 PMID:14576322 -4.2.99.18 dna containing 5-hydroxy-2'-deoxyuridine/g escherichia coli 0.0267 0.0267 1 PMID:14576322 -4.2.99.18 dna containing 5-oh-c/a homo sapiens 0.0005 0.0004165 2 PMID:11380260 -4.2.99.18 dna containing 5-oh-c/g homo sapiens 0.000833 0.00075 2 PMID:11380260 -4.2.99.18 dna containing an abasic site homo sapiens 10.0 5.8 2 PMID:15380100 -4.2.99.18 dna containing apurinic/apyrimidinic site homo sapiens 2.4 2.4 1 PMID:12531388 -4.2.99.18 dna containing apurinic/apyrimidinic sites escherichia coli 0.01067 0.00975 2 PMID:17002303 -4.2.99.18 dna containing apurinic/apyrimidinic sites homo sapiens 10.0 10.0 1 PMID:19123919 -4.2.99.18 dna containing dihydrouracil homo sapiens 0.002 0.002 1 PMID:9705289 -4.2.99.18 dna containing tetrahydrofuranyl/g escherichia coli 0.0283 0.0283 1 PMID:14576322 -4.2.99.18 dna containing tetrahydrofuranyl/g saccharomyces cerevisiae 0.01 0.01 1 PMID:14576322 -4.2.99.18 dna with 2-deoxyribonolactone homo sapiens 2.3 2.3 1 PMID:12531388 -4.2.99.18 double-stranded dna with abasic sites homo sapiens 4.1 4.1 1 PMID:15084314 -4.2.99.18 duplex oligonucleotide containing a 5,6-dihydro-2'-deoxyuridine*g pair homo sapiens 0.0027 0.0027 1 PMID:14704345 -4.2.99.18 duplex oligonucleotide containing a alpha-2'-deoxyadenosine*t pair homo sapiens 0.002 0.002 1 PMID:14704345 -4.2.99.18 duplex oligonucleotide containing a tetrahydrofuran*g pair homo sapiens 0.002 0.002 1 PMID:14704345 -4.2.99.18 oligomer with g/u pair homo sapiens 10.0 10.0 1 PMID:12480540 -4.2.99.18 single-stranded dna with abasic sites homo sapiens 4.2 4.2 1 PMID:15084314 -4.2.99.18 synthetic oligonucleotide homo sapiens 1.49 1.49 1 PMID:31150756 -4.2.99.18 thf-containing oligonucleotide homo sapiens 12120.0 12120.0 1 PMID:19181704 -4.2.99.18 thf-containing oligonucleotide leishmania major 19260.0 19260.0 1 PMID:19181704 -4.2.99.18 thf.t dna duplex deinococcus radiodurans 0.067 0.067 1 PMID:33117296 -4.2.99.20 (1r,2s,5s,6s)-2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate escherichia coli 147.0 77.75 2 PMID:19545176;PMID:24737327 -4.2.99.20 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate escherichia coli 167.0 157.0 2 PMID:18284213 -4.2.99.21 isochorismate mycobacterium tuberculosis 0.8 0.41750000000000004 2 PMID:17240979;PMID:20512795 -4.2.99.21 isochorismate pseudomonas aeruginosa 1.76 0.43 7 PMID:11937513;PMID:16036918;PMID:16248620;PMID:19432488;PMID:22970849;PMID:24055536 -4.2.99.21 isochorismate yersinia enterocolitica 0.092 0.092 1 PMID:24055536 -4.2.99.22 1,6-tuliposide d tulipa gesneriana 3300.0 3300.0 1 PMID:30284210 -4.2.99.22 6-tuliposide a tulipa gesneriana 3900.0 2780.0 4 PMID:22474185;PMID:23649245;PMID:30284210;PMID:30595444 -4.2.99.22 6-tuliposide b tulipa gesneriana 610.0 495.0 4 PMID:22474185;PMID:23649245;PMID:30284210;PMID:30595444 -4.2.99.22 tuliposide f tulipa gesneriana 780.0 780.0 1 PMID:30284210 -4.2.99.23 1,6-tuliposide d tulipa gesneriana 35.0 35.0 1 PMID:30284210 -4.2.99.23 6-tuliposide a tulipa gesneriana 8.7 6.484999999999999 2 PMID:30284210;PMID:30595444 -4.2.99.23 6-tuliposide b tulipa gesneriana 2000.0 1560.0 2 PMID:30284210;PMID:30595444 -4.2.99.23 tuliposide f tulipa gesneriana 580.0 580.0 1 PMID:30284210 -4.3.1.1 fumarate bacillus sp. ym55-1 90.0 90.0 1 PMID:18844200 -4.3.1.1 fumarate lacticaseibacillus paracasei 0.45 0.45 1 * -4.3.1.1 fumarate pseudomonas aeruginosa 13.64 13.64 1 PMID:27988856 -4.3.1.1 hydrazine bacillus sp. ym55-1 94.0 93.0 2 PMID:18844200 -4.3.1.1 hydroxylamine bacillus sp. ym55-1 99.0 65.0 2 PMID:18844200 -4.3.1.1 l-aspartate bacillus sp. (in: firmicutes) 40.0 40.0 1 PMID:21661762 -4.3.1.1 l-aspartate bacillus sp. ym55-1 40.0 40.0 2 PMID:18844200;PMID:19490103 -4.3.1.1 l-aspartate escherichia coli 180.0 180.0 1 * -4.3.1.1 l-aspartate lacticaseibacillus paracasei 6.7 6.7 1 * -4.3.1.1 l-aspartate pseudomonas aeruginosa 4.908 4.908 1 PMID:27988856 -4.3.1.1 l-aspartate pseudomonas fluorescens 129.7 74.89999999999999 2 PMID:35114050 -4.3.1.1 l-aspartate yersinia pestis 0.1 0.1 1 PMID:18451035 -4.3.1.1 l-aspartate yersinia pseudotuberculosis 87.0 87.0 1 PMID:18451035 -4.3.1.1 l-phenylalanine lacticaseibacillus paracasei 4.96 4.96 1 * -4.3.1.1 l-phenylalanine pseudomonas aeruginosa 8.002 8.002 1 PMID:27988856 -4.3.1.1 l-tyrosine lacticaseibacillus paracasei 0.02 0.02 1 * -4.3.1.1 nh3 bacillus sp. ym55-1 89.0 74.0 2 PMID:18844200 -4.3.1.15 d-2,3-diaminopropanoate escherichia coli 53.7 49.14 2 PMID:22505717;PMID:29294403 -4.3.1.15 d-2,3-diaminopropanoate salmonella enterica subsp. enterica serovar typhimurium 375.8 209.15 2 PMID:22904288;PMID:29294403 -4.3.1.15 d-serine salmonella enterica subsp. enterica serovar typhimurium 5.17 5.17 1 PMID:22904288 -4.3.1.15 dl-2,3-diaminopropanoate salmonella enterica subsp. enterica serovar typhimurium 69.17 64.67 2 PMID:22904288 -4.3.1.15 l-2,3-diaminopropanoate escherichia coli 24.6 21.8 2 PMID:22505717;PMID:29294403 -4.3.1.15 l-2,3-diaminopropanoate salmonella enterica subsp. enterica serovar typhimurium 43.3 43.065 2 PMID:22904288;PMID:29294403 -4.3.1.16 erythro-3-hydroxy-d-aspartate pseudomonas sp. n99 2.19 2.19 1 PMID:28290777 -4.3.1.16 threo-3-hydroxy-l-aspartate pseudomonas sp. n99 8.61 8.61 1 PMID:28290777 -4.3.1.17 beta-chloro-l-alanine mus musculus 2.6 2.6 1 PMID:16185077 -4.3.1.17 d-serine mus musculus 14.5 1.621 4 PMID:15536068;PMID:16185077 -4.3.1.17 d-threonine mus musculus 0.3 0.3 1 PMID:15536068 -4.3.1.17 l-ser legionella pneumophila 330.0 330.0 1 PMID:21878319 -4.3.1.17 l-serine bacillus subtilis 585.0 324.5 4 PMID:22686449 -4.3.1.17 l-serine bombyx mori 0.21 0.21 1 PMID:35325141 -4.3.1.17 l-serine entamoeba histolytica 3.0 3.0 1 PMID:19931317 -4.3.1.17 l-serine escherichia coli 544.0 490.0 2 PMID:15155761;PMID:15498577 -4.3.1.17 l-serine homo sapiens 2.77 0.62 4 PMID:29899358;PMID:30687716;PMID:33249721 -4.3.1.17 l-serine legionella pneumophila 330.0 308.0 2 PMID:22686449;PMID:26971469 -4.3.1.17 l-serine mus musculus 4.0 1.9829999999999999 4 PMID:15536068;PMID:16185077 -4.3.1.17 l-serine o-sulfate mus musculus 0.49 0.49 1 PMID:16185077 -4.3.1.17 l-threo-3-hydroxyaspartate mus musculus 31.0 31.0 1 PMID:16185077 -4.3.1.17 l-threonine entamoeba histolytica 5.2 5.2 1 PMID:19931317 -4.3.1.17 l-threonine mus musculus 10.5 10.5 1 PMID:16185077 -4.3.1.18 beta-chloro-d-alanine saccharomyces cerevisiae 0.48 0.24 5 PMID:17937657;PMID:22176976 -4.3.1.18 d-allo-threonine saccharomyces cerevisiae 0.13 0.13 1 PMID:22176976 -4.3.1.18 d-allothreonine escherichia coli 0.92 0.516 2 PMID:6406501 -4.3.1.18 d-ser escherichia coli 118.0 39.0 4 PMID:6406501 -4.3.1.18 d-serine bombyx mori 0.2 0.2 1 PMID:35325141 -4.3.1.18 d-serine dictyostelium discoideum 2.6 2.6 1 PMID:29740415 -4.3.1.18 d-serine escherichia coli 15.7 15.7 1 PMID:16221850 -4.3.1.18 d-serine gallus gallus 6.08 3.4455 2 PMID:17977854 -4.3.1.18 d-serine homo sapiens 0.028 0.028 1 PMID:29899358 -4.3.1.18 d-serine saccharomyces cerevisiae 17.0 13.1 6 PMID:17937657;PMID:22176976;PMID:22519530;PMID:24881047 -4.3.1.18 d-thr escherichia coli 0.95 0.95 1 PMID:6406501 -4.3.1.18 d-threonine gallus gallus 0.0512 0.0512 1 PMID:17977854 -4.3.1.18 d-threonine saccharomyces cerevisiae 0.43 0.39 3 PMID:17937657;PMID:22176976 -4.3.1.18 l-allothreonine escherichia coli 1.8 1.8 1 PMID:6406501 -4.3.1.18 l-ser escherichia coli 0.153 0.14 3 PMID:6406501 -4.3.1.18 l-serine gallus gallus 0.197 0.197 1 PMID:17977854 -4.3.1.18 l-thr escherichia coli 19.6 18.4 2 PMID:6406501 -4.3.1.19 beta-chloro-l-alanine mycolicibacterium smegmatis 27.15 27.15 1 PMID:30226377 -4.3.1.19 l-allo-threonine mycolicibacterium smegmatis 5.69 5.69 1 PMID:30226377 -4.3.1.19 l-ser entamoeba histolytica 3.0 3.0 1 PMID:19931317 -4.3.1.19 l-ser rattus norvegicus 243.0 243.0 1 PMID:9795257 -4.3.1.19 l-serine mycolicibacterium smegmatis 32.59 32.59 1 PMID:30226377 -4.3.1.19 l-thr entamoeba histolytica 5.2 5.2 1 PMID:19931317 -4.3.1.19 l-thr rattus norvegicus 287.0 287.0 1 PMID:9795257 -4.3.1.19 l-threonine escherichia coli 1414.0 1414.0 1 PMID:30259222 -4.3.1.19 l-threonine mycolicibacterium smegmatis 9.42 9.42 1 PMID:30226377 -4.3.1.2 (2s,3s)-3-ethylaspartic acid carboxydothermus hydrogenoformans 78.0 47.0 2 PMID:22005738 -4.3.1.2 fumarate escherichia coli 87.0 87.0 1 * -4.3.1.2 l-aspartate carboxydothermus hydrogenoformans 141.0 141.0 1 PMID:32437404 -4.3.1.2 l-aspartate citrobacter amalonaticus 4.4 4.4 1 PMID:32437404 -4.3.1.2 l-aspartate clostridium tetanomorphum 0.031 0.031 1 PMID:32437404 -4.3.1.2 l-aspartate escherichia coli 44.0 44.0 1 * -4.3.1.2 l-threo-3-methylaspartate carboxydothermus hydrogenoformans 1.0 1.0 1 PMID:32437404 -4.3.1.2 l-threo-3-methylaspartate citrobacter amalonaticus 17.6 17.6 1 PMID:32437404 -4.3.1.2 l-threo-3-methylaspartate clostridium tetanomorphum 467.0 240.0 3 PMID:11320320;PMID:32437404 -4.3.1.2 l-threo-3-methylaspartate escherichia coli 35.0 35.0 1 * -4.3.1.2 l-threo-3-methylaspartic acid clostridium tetanomorphum 89.0 89.0 1 PMID:19670200 -4.3.1.2 mesaconate clostridium tetanomorphum 61.0 61.0 1 PMID:23905011 -4.3.1.2 mesaconate escherichia coli 103.0 103.0 1 * -4.3.1.2 mesaconic acid clostridium tetanomorphum 61.0 61.0 1 PMID:19670200 -4.3.1.23 l-phenylalanine cereibacter sphaeroides 0.6 0.6 1 PMID:19343746 -4.3.1.23 l-phenylalanine rhodobacter capsulatus 15.1 15.1 1 PMID:11852088 -4.3.1.23 l-tyrosine cereibacter sphaeroides 0.9 0.9 1 PMID:19343746 -4.3.1.23 l-tyrosine chryseobacterium luteum sp. nov 31.0 31.0 1 PMID:35352477 -4.3.1.23 l-tyrosine rhodobacter capsulatus 27.7 27.7 1 PMID:11852088 -4.3.1.23 l-tyrosine rhodotorula glutinis 114.0 114.0 1 PMID:27401923 -4.3.1.23 l-tyrosine rivularia sp. pcc 7116 55.0 55.0 1 PMID:35352477 -4.3.1.23 l-tyrosinol cereibacter sphaeroides 0.12 0.12 1 PMID:19343746 -4.3.1.24 (2e)-3-(3-fluorophenyl)prop-2-enoic acid trichormus variabilis 0.08 0.08 1 PMID:25037641 -4.3.1.24 (2e)-3-(3-hydroxyphenyl)prop-2-enoic acid trichormus variabilis 0.61 0.61 1 PMID:25037641 -4.3.1.24 (2e)-3-(4-fluorophenyl)prop-2-enoic acid trichormus variabilis 0.09 0.09 1 PMID:25037641 -4.3.1.24 (2e)-3-(4-nitrophenyl)prop-2-enoic acid trichormus variabilis 3.81 3.81 1 PMID:25037641 -4.3.1.24 (2e)-3-(pyridin-3-yl)prop-2-enoic acid trichormus variabilis 0.14 0.14 1 PMID:25037641 -4.3.1.24 (2e)-3-(pyridin-4-yl)prop-2-enoic acid trichormus variabilis 1.06 1.06 1 PMID:25037641 -4.3.1.24 (2e)-3-[4-(trifluoromethyl)phenyl]prop-2-enoic acid trichormus variabilis 3.14 3.14 1 PMID:25037641 -4.3.1.24 (2e)-3-bromo-cinnamic acid rhodotorula graminis 2.22 2.22 1 * -4.3.1.24 (2e)-3-fluoro-cinnamic acid rhodotorula graminis 2.52 2.52 1 * -4.3.1.24 (2e)-3-nitro-cinnamic acid rhodotorula graminis 1.06 1.06 1 * -4.3.1.24 (2e)-3-phenylprop-2-enoic acid trichormus variabilis 0.03 0.03 1 PMID:25037641 -4.3.1.24 (2e)-4-bromo-cinnamic acid rhodotorula graminis 0.33 0.33 1 * -4.3.1.24 (2e)-4-fluoro-cinnamic acid rhodotorula graminis 2.14 2.14 1 * -4.3.1.24 (2s)-2-amino-3-(3-fluorophenyl)propanoic acid trichormus variabilis 1.1 1.1 1 PMID:25037641 -4.3.1.24 (2s)-2-amino-3-(3-hydroxyphenyl)propanoic acid trichormus variabilis 0.89 0.89 1 PMID:25037641 -4.3.1.24 (2s)-2-amino-3-(4-fluorophenyl)propanoic acid trichormus variabilis 1.06 1.06 1 PMID:25037641 -4.3.1.24 (2s)-2-amino-3-(4-nitrophenyl)propanoic acid trichormus variabilis 1.08 1.08 1 PMID:25037641 -4.3.1.24 (2s)-2-amino-3-(pyridin-3-yl)propanoic acid trichormus variabilis 0.91 0.91 1 PMID:25037641 -4.3.1.24 (2s)-2-amino-3-(pyridin-4-yl)propanoic acid trichormus variabilis 0.61 0.61 1 PMID:25037641 -4.3.1.24 (2s)-2-amino-3-[4-(trifluoromethyl)phenyl]propanoic acid trichormus variabilis 0.82 0.82 1 PMID:25037641 -4.3.1.24 (2s)-2-amino-3-phenylpropanoic acid trichormus variabilis 0.49 0.49 1 PMID:25037641 -4.3.1.24 l-4-meo-phe petroselinum crispum 0.012 0.012 1 PMID:32486192 -4.3.1.24 l-phe arabidopsis thaliana 3.2 2.4 4 PMID:15276452 -4.3.1.24 l-phe bambusa oldhamii 21.3 16.3 5 PMID:20064614;PMID:21035152 -4.3.1.24 l-phe cistanche deserticola 3.36 3.36 1 PMID:21104014 -4.3.1.24 l-phe jatropha curcas 1.73 1.73 1 PMID:21706349 -4.3.1.24 l-phe petroselinum crispum 22.0 22.0 1 PMID:7925471 -4.3.1.24 l-phe streptomyces maritimus 4.79 4.79 1 PMID:15937191 -4.3.1.24 l-phenylalanine anthoceros agrestis 288.0 144.1765 2 PMID:35796843 -4.3.1.24 l-phenylalanine arabidopsis thaliana 115.8 65.0 3 PMID:17185227;PMID:28392421 -4.3.1.24 l-phenylalanine bambusa oldhamii 16.04 10.12 5 PMID:20064614;PMID:20354908 -4.3.1.24 l-phenylalanine dolichospermum flos-aquae 0.06 0.06 1 PMID:31581382 -4.3.1.24 l-phenylalanine ephedra sinica 0.588 0.48650000000000004 4 PMID:19043198 -4.3.1.24 l-phenylalanine kitagawia praeruptora 58.5 58.5 1 PMID:30448740 -4.3.1.24 l-phenylalanine limnospira platensis 0.24 0.24 1 PMID:31581382 -4.3.1.24 l-phenylalanine nicotiana tabacum 1.53 1.115 4 PMID:19725811 -4.3.1.24 l-phenylalanine nostoc punctiforme 1.96 1.96 1 PMID:17240984 -4.3.1.24 l-phenylalanine petroselinum crispum 2.64 1.4869999999999999 4 PMID:26345352;PMID:28392421;PMID:28405665;PMID:32486192 -4.3.1.24 l-phenylalanine photorhabdus luminescens 73.28 73.28 1 PMID:33411135 -4.3.1.24 l-phenylalanine rhodotorula glutinis 25.7 25.7 1 PMID:23338700 -4.3.1.24 l-phenylalanine sorghum bicolor 2.2 2.2 1 PMID:29196539 -4.3.1.24 l-phenylalanine spirulina 15.35 15.35 1 PMID:35713742 -4.3.1.24 l-phenylalanine trichormus variabilis 4.6 4.300000000000001 4 PMID:17240984;PMID:18556022;PMID:23999738;PMID:28343264 -4.3.1.24 l-propargylglycine petroselinum crispum 0.37 0.37 1 PMID:26345352 -4.3.1.24 l-styrylalanine petroselinum crispum 0.0471 0.0471 1 PMID:28405665 -4.3.1.24 l-tyr bambusa oldhamii 0.54 0.28500000000000003 2 PMID:21035152 -4.3.1.24 l-tyr jatropha curcas 0.11 0.11 1 PMID:21706349 -4.3.1.24 l-tyr petroselinum crispum 0.3 0.3 1 PMID:7925471 -4.3.1.24 l-tyrosine anthoceros agrestis 0.081 0.061 2 PMID:35796843 -4.3.1.24 l-tyrosine arabidopsis thaliana 0.084 0.067 2 PMID:17185227;PMID:28392421 -4.3.1.24 l-tyrosine photorhabdus luminescens 5.59 5.59 1 PMID:33411135 -4.3.1.24 n-methyl-l-phenylalanine petroselinum crispum 0.22 0.22 1 * -4.3.1.24 rac-(e)-2-amino-5-(4-chlorophenyl)pent-4-enoic acid petroselinum crispum 0.00024 0.00024 1 PMID:28405665 -4.3.1.24 rac-(e)-2-amino-5-phenylpent-4-enoic acid petroselinum crispum 0.0062 0.0062 1 PMID:28405665 -4.3.1.24 trans-cinnamate arabidopsis thaliana 0.39 0.39 1 PMID:28392421 -4.3.1.24 trans-cinnamate dolichospermum flos-aquae 0.32 0.32 1 PMID:31581382 -4.3.1.24 trans-cinnamate limnospira platensis 1.25 1.25 1 PMID:31581382 -4.3.1.24 trans-cinnamate petroselinum crispum 0.46 0.46 1 PMID:28392421 -4.3.1.24 trans-cinnamate rhodotorula graminis 1.97 1.97 1 * -4.3.1.25 l-dopa sorghum bicolor 0.3 0.3 1 PMID:29196539 -4.3.1.25 l-phe bambusa oldhamii 16.32 16.32 1 PMID:21035152 -4.3.1.25 l-phenylalanine cutaneotrichosporon cutaneum 9.8 9.8 1 * -4.3.1.25 l-phenylalanine phanerodontia chrysosporium 3.3 3.3 1 * -4.3.1.25 l-phenylalanine rhodotorula glutinis 1.6 1.565 2 * -4.3.1.25 l-phenylalanine rhodotorula toruloides 5.99 5.99 1 PMID:28392421 -4.3.1.25 l-phenylalanine sorghum bicolor 0.37 0.33999999999999997 2 PMID:29196539 -4.3.1.25 l-tyr bambusa oldhamii 0.54 0.54 1 PMID:21035152 -4.3.1.25 l-tyrosine cutaneotrichosporon cutaneum 1.44 1.44 1 * -4.3.1.25 l-tyrosine phanerodontia chrysosporium 1.3 1.3 1 * -4.3.1.25 l-tyrosine rhodotorula glutinis 0.93 0.73 2 * -4.3.1.25 l-tyrosine rhodotorula toruloides 1.02 1.02 1 PMID:28392421 -4.3.1.25 l-tyrosine sorghum bicolor 2.34 2.05 2 PMID:29196539 -4.3.1.25 trans-cinnamate rhodotorula toruloides 1.04 1.04 1 PMID:28392421 -4.3.1.27 d-serine delftia sp. ht23 8.68 8.68 1 PMID:20843822 -4.3.1.27 d-threo-3-hydroxyaspartate delftia sp. ht23 10.93 10.93 1 PMID:20843822 -4.3.1.27 l-erythro-3-hydroxyaspartate delftia sp. ht23 8.68 8.68 1 PMID:20843822 -4.3.1.27 l-serine delftia sp. ht23 0.18 0.18 1 PMID:20843822 -4.3.1.27 l-threo-3-hydroxyaspartate delftia sp. ht23 3.03 3.03 1 PMID:20843822 -4.3.1.28 l-lysine streptomyces hygroscopicus 0.61 0.61 1 PMID:16536560 -4.3.1.29 2-amino-2-deoxy-d-gluconate 6-phosphate salmonella enterica subsp. enterica serovar typhimurium 27.4 27.4 1 PMID:29277660 -4.3.1.29 2-amino-2-deoxy-d-gluconate 6-phosphate sphingobium sp. 20006fa 27.4 27.4 1 PMID:35953460 -4.3.1.3 l-histidine pseudomonas putida 255.0 170.5 2 PMID:11732994;PMID:8251759 -4.3.1.3 l-histidine thermoplasma acidophilum 1.7 1.01 3 PMID:36238657 -4.3.1.30 dtdp-4-amino-4,6-dideoxy-alpha-d-glucopyranose streptomyces venezuelae 0.017 0.017 1 PMID:19746907 -4.3.1.33 (1r)-(2-amino-1-hydroxyethyl)phosphonate vibrio splendidus 5.3 5.3 1 PMID:33830741 -4.3.1.6 acryloyl-coa anaerotignum propionicum 195.0 195.0 1 PMID:15670161 -4.3.1.6 beta-alanyl-coa anaerotignum propionicum 25.0 25.0 1 PMID:15670161 -4.3.1.6 nh3 anaerotignum propionicum 301.0 301.0 1 PMID:15670161 -4.3.1.7 (r)-2-aminopropanol salmonella enterica subsp. enterica serovar typhimurium 0.067 0.067 1 PMID:16734439 -4.3.1.7 (s)-2-aminopropanol salmonella enterica subsp. enterica serovar typhimurium 0.12 0.12 1 PMID:16734439 -4.3.1.7 ethanolamine escherichia coli 770.0 605.0 2 PMID:24735254 -4.3.1.7 ethanolamine salmonella enterica subsp. enterica serovar typhimurium 55.0 22.7 7 PMID:16734439;PMID:18444665;PMID:23374068 -4.3.2.1 2-(nomega-l-arginino)succinate limnospira platensis 2.2 2.2 1 PMID:35583703 -4.3.2.1 2-(nomega-l-arginino)succinate mycobacterium tuberculosis 14.63 12.010000000000002 2 PMID:29044950;PMID:30665717 -4.3.2.1 2-(nomega-l-arginino)succinate nostoc sp. pcc 7120 = fachb-418 8.71 8.71 1 PMID:35583703 -4.3.2.1 2-(nomega-l-arginino)succinate synechocystis sp. pcc 6803 6.78 6.78 1 PMID:35583703 -4.3.2.1 argininosuccinate anas platyrhynchos 2930.0 1467.45 2 PMID:10029537;PMID:1815504 -4.3.2.1 argininosuccinate anser sp. 2500.0 2500.0 1 PMID:1815504 -4.3.2.1 argininosuccinate homo sapiens 3.28 3.28 1 PMID:10029537 -4.3.2.1 n,n'-bis(tert-butoxycarbonyl)-5-[(3-aminopropyl)amino]pentan-1-ol homo sapiens 34.5 34.5 1 PMID:11747432 -4.3.2.10 5-[(5-phospho-1-deoxy-d-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-beta-d-ribosyl)imidazole-4-carboxamide escherichia coli 8.5 7.3 2 PMID:8494895 -4.3.2.10 5-[(5-phospho-1-deoxy-d-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-beta-d-ribosyl)imidazole-4-carboxamide saccharomyces cerevisiae 5.4 3.9 3 PMID:10733892;PMID:12795596 -4.3.2.10 5-[(5-phospho-1-deoxy-d-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-beta-d-ribosyl)imidazole-4-carboxamide thermotoga maritima 2.2 1.5 2 PMID:11264293 -4.3.2.10 l-glutamine escherichia coli 9.1 9.1 1 PMID:8494895 -4.3.2.10 l-glutamine saccharomyces cerevisiae 6.9 6.050000000000001 2 PMID:10733892;PMID:16142895 -4.3.2.10 l-glutamine thermotoga maritima 5.92 0.208 20 PMID:11264293;PMID:28396388;PMID:29468164;PMID:35412310 -4.3.2.10 n1-[(5'-phosphoribulosyl)formimino]-5-aminoimidazole-4-carboxamido-1-beta-d-ribofuranosyl 5'-phosphate saccharomyces cerevisiae 5.4 3.1225 2 PMID:16142895 -4.3.2.10 nh4+ escherichia coli 8.8 8.8 1 PMID:8494895 -4.3.2.10 nh4+ saccharomyces cerevisiae 0.6 0.6 1 PMID:10733892 -4.3.2.10 nh4+ thermotoga maritima 2.0 2.0 1 PMID:11264293 -4.3.2.2 (s)-2-[5-amino-1-(5-phospho-d-ribosyl)imidazole-4-carboxamido]succinate leishmania braziliensis 337.0 337.0 1 * -4.3.2.2 adenylosuccinate bacillus subtilis 1.74 1.74 1 PMID:17322529 -4.3.2.2 amp plasmodium falciparum 2.9 2.9 1 PMID:19111634 -4.3.2.2 fumarate plasmodium falciparum 2.9 2.9 1 PMID:19111634 -4.3.2.2 succinyladenosine monophosphate mycobacterium tuberculosis 0.1 0.1 1 PMID:24479855 -4.3.2.2 succinyladenosine monophosphate mycolicibacterium smegmatis 0.7 0.7 1 PMID:24479855 -4.3.2.2 succinyladenosine monophosphate plasmodium falciparum 7.5 7.5 1 PMID:19111634 -4.3.2.3 ureidoglycolate phaseolus vulgaris 0.018 0.018 1 PMID:16333637 -4.3.2.5 n-2,4,6-trinitrophenyl-d-tyr-l-val-(s)-alpha-hydroxy-gly homo sapiens 25.7 14.45 2 PMID:19170548 -4.3.2.5 nalpha-acetyl-tyr-val-alpha-hydroxyglycine bos taurus 220.0 220.0 1 PMID:1902227 -4.3.2.5 nalpha-acetyl-tyr-val-alpha-hydroxyglycine rattus norvegicus 380.0 92.0 3 PMID:12369828;PMID:8486658 -4.3.2.7 glutathione homo sapiens 0.27 0.27 1 PMID:27913623 -4.3.2.7 glutathione mus musculus 0.13 0.13 1 PMID:27913623 -4.3.2.8 l-gamma-glutamyl-(2s)-2-methylbutylamine oryctolagus cuniculus 0.21 0.21 1 PMID:22120669 -4.3.2.8 l-gamma-glutamyl-2-methylbutylamine oryctolagus cuniculus 0.19 0.19 1 PMID:22120669 -4.3.2.8 l-gamma-glutamyl-beta-alanine oryctolagus cuniculus 0.18 0.18 1 PMID:22120669 -4.3.2.8 l-gamma-glutamyl-n-butylamine oryctolagus cuniculus 0.21 0.21 1 PMID:22120669 -4.3.2.8 l-gamma-glutamyl-n-propylamine oryctolagus cuniculus 0.23 0.23 1 PMID:22120669 -4.3.2.8 l-gamma-glutamylbenzylamine oryctolagus cuniculus 0.4 0.4 1 PMID:22120669 -4.3.2.8 l-gamma-glutamylcyclopentylamine oryctolagus cuniculus 0.076 0.076 1 PMID:22120669 -4.3.2.8 l-gamma-glutamylneohexylamine oryctolagus cuniculus 0.18 0.18 1 PMID:22120669 -4.3.2.8 nepsilon-(l-gamma-glutamyl)-d-lysine oryctolagus cuniculus 0.25 0.25 1 PMID:22120669 -4.3.2.8 nepsilon-(l-gamma-glutamyl)-l-lysine oryctolagus cuniculus 0.2 0.2 1 PMID:22120669 -4.3.2.8 s-(cyclohexylamine)-l-cysteine oryctolagus cuniculus 0.26 0.26 1 PMID:22120669 -4.3.2.8 s-(n-butylcarbamyl)-l-cysteine oryctolagus cuniculus 0.27 0.27 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-(+)-3-aminobutyric acid oryctolagus cuniculus 0.054 0.054 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-(+)-3-aminoisobutyric acid oryctolagus cuniculus 0.071 0.071 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-anilide oryctolagus cuniculus 0.036 0.036 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-benzylamine oryctolagus cuniculus 0.4 0.4 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-beta-alanine oryctolagus cuniculus 0.18 0.18 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-beta-phenethylamine oryctolagus cuniculus 0.17 0.17 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-cyclopentylamine oryctolagus cuniculus 0.076 0.076 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-ethylamine oryctolagus cuniculus 0.038 0.038 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-glycine oryctolagus cuniculus 0.14 0.14 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-methylamine oryctolagus cuniculus 0.02 0.02 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-n-butylamine oryctolagus cuniculus 0.21 0.21 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-n-propylamine oryctolagus cuniculus 0.23 0.23 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-neohexylamine oryctolagus cuniculus 0.18 0.18 1 PMID:22120669 -4.3.2.9 5-l-glutamyl-neopentylamine oryctolagus cuniculus 0.035 0.035 1 PMID:22120669 -4.3.2.9 gamma-glutamyl-l-alanine homo sapiens 18.3 18.3 1 PMID:18515354 -4.3.2.9 glutathione arabidopsis thaliana 0.64 0.3765 2 PMID:25716890 -4.3.2.9 glutathione ralstonia solanacearum 52.8 52.8 1 PMID:26823466 -4.3.2.9 l-2-amino-3-(3-n-butylureido)-propionic acid oryctolagus cuniculus 0.001 0.001 1 PMID:22120669 -4.3.2.9 nepsilon-(5-l-glutamyl)-d-lysine oryctolagus cuniculus 0.25 0.25 1 PMID:22120669 -4.3.2.9 nepsilon-(5-l-glutamyl)-l-lysine oryctolagus cuniculus 0.2 0.2 1 PMID:22120669 -4.3.2.9 o-(n-butylcarbamyl)-l-serine oryctolagus cuniculus 12.0 12.0 1 PMID:22120669 -4.3.2.9 s-(cyclohexylamine)-l-cysteine oryctolagus cuniculus 0.26 0.26 1 PMID:22120669 -4.3.2.9 s-(n-butylcarbamyl)-l-cysteine oryctolagus cuniculus 0.27 0.27 1 PMID:22120669 -4.3.2.9 s-(n-propylcarbamyl)-l-cysteine oryctolagus cuniculus 0.24 0.24 1 PMID:22120669 -4.3.3.2 2-(1h-indol-3-yl)propan-1-amine rauvolfia serpentina 8.42 8.42 1 PMID:34994203 -4.3.3.2 tryptamine rauvolfia serpentina 14.35 14.35 1 PMID:34994203 -4.3.3.6 d-glyceraldehyde 3-phosphate geobacillus kaustophilus 0.00017 0.00017 1 PMID:25568319 -4.3.3.6 d-ribose 5-phosphate bacillus subtilis 0.004 0.0006 5 PMID:16030023;PMID:17189272;PMID:21283685 -4.3.3.6 d-ribose 5-phosphate geobacillus kaustophilus 0.00017 0.00017 1 PMID:25568319 -4.3.3.6 d-ribulose 5-phosphate bacillus subtilis 0.0007 0.0007 1 PMID:17189272 -4.3.3.6 l-glutamine bacillus subtilis 0.127 0.0295 3 PMID:16030023;PMID:21283685 -4.3.3.6 l-glutamine geobacillus kaustophilus 0.001 0.001 1 PMID:25568319 -4.3.3.7 (s)-aspartate 4-semialdehyde escherichia coli 124.0 124.0 3 PMID:15066435;PMID:15194235;PMID:18937497 -4.3.3.7 l-aspartate 4-semialdehyde corynebacterium glutamicum 213.0 213.0 1 PMID:18930704 -4.3.3.7 l-aspartate 4-semialdehyde escherichia coli 9.8 9.8 1 PMID:20709017 -4.3.3.7 l-aspartate 4-semialdehyde mycobacterium tuberculosis 138.0 138.0 1 PMID:21672512 -4.3.3.7 l-aspartate 4-semialdehyde thermotoga maritima 465.0 300.5 2 PMID:21803176 -4.3.3.7 l-aspartate-4-semialdehyde arabidopsis thaliana 180.0 136.5 2 PMID:33586321 -4.3.3.7 l-aspartate-4-semialdehyde escherichia coli 223.0 223.0 1 PMID:4910051 -4.3.3.7 l-aspartate-4-semialdehyde pseudomonas aeruginosa 44.0 36.5 2 PMID:31330085 -4.3.3.7 l-aspartate-4-semialdehyde triticum aestivum 56.0 56.0 1 PMID:29744651 -4.3.3.7 l-aspartate-4-semialdehyde vibrio cholerae 46.0 40.0 2 PMID:29337198 -4.3.3.7 pyruvate arabidopsis thaliana 180.0 136.5 2 PMID:33586321 -4.3.3.7 pyruvate bacillus anthracis 92.0 84.0 2 PMID:19595801;PMID:19948665 -4.3.3.7 pyruvate escherichia coli 124.0 75.0 7 PMID:15194235;PMID:19236959;PMID:19338756;PMID:19919824;PMID:20353808;PMID:20709017 -4.3.3.7 pyruvate mycobacterium tuberculosis 138.0 138.0 1 PMID:21672512 -4.3.3.7 pyruvate neisseria meningitidis 46.7 46.7 1 PMID:19236959 -4.3.3.7 pyruvate pseudomonas aeruginosa 44.0 36.5 2 PMID:31330085 -4.3.3.7 pyruvate staphylococcus aureus 70.0 70.0 1 PMID:18684709 -4.3.3.7 pyruvate thermotoga maritima 465.0 300.5 2 PMID:21803176 -4.3.3.7 pyruvate vibrio cholerae 46.0 40.0 2 PMID:29337198 -4.3.3.8 cystathionine mimosa pudica 310.0 310.0 1 PMID:31368041 -4.3.3.8 mimosine arthrobacter sp. ryudai-s1 302750.0 302750.0 1 PMID:35908235 -4.3.3.8 mimosine mimosa pudica 12180.0 12180.0 1 PMID:31368041 -4.3.99.3 6-carboxy-5,6,7,8-tetrahydropterin bacillus subtilis 5.4 5.4 1 PMID:23194065 -4.3.99.4 choline oleidesulfovibrio alaskensis 747.0 452.0 2 PMID:24854437;PMID:27642068 -4.4.1.1 cys treponema denticola 12.0 12.0 1 PMID:10194060 -4.4.1.1 cystathionine homo sapiens 1.9 1.9 1 PMID:10212249 -4.4.1.1 djenkolic acid toxoplasma gondii 0.24 0.24 1 PMID:30036991 -4.4.1.1 dl-cystathionine aspergillus carneus 0.13 0.12 2 PMID:26316161 -4.4.1.1 l-cystathionine bacillus cereus 1.44 1.44 1 PMID:33301683 -4.4.1.1 l-cystathionine homo sapiens 7.5 1.9 3 PMID:18476726;PMID:19019829 -4.4.1.1 l-cystathionine lactiplantibacillus plantarum 0.49 0.49 1 PMID:32913258 -4.4.1.1 l-cystathionine saccharomyces cerevisiae 1.81 1.51 3 PMID:19370061;PMID:24291053 -4.4.1.1 l-cystathionine toxoplasma gondii 2.0 2.0 1 PMID:30036991 -4.4.1.1 l-cysteine homo sapiens 0.67 0.535 4 PMID:18476726;PMID:19019829;PMID:19961860 -4.4.1.1 l-cysteine lactiplantibacillus plantarum 0.3 0.3 1 PMID:32913258 -4.4.1.1 l-cysteine saccharomyces cerevisiae 0.15 0.15 1 PMID:24291053 -4.4.1.1 l-cysteine toxoplasma gondii 0.009 0.009 1 PMID:30036991 -4.4.1.1 l-cystine lactiplantibacillus plantarum 0.12 0.12 1 PMID:32913258 -4.4.1.1 l-homocysteine homo sapiens 3.7 3.6 2 PMID:18476726 -4.4.1.1 l-homocysteine lactiplantibacillus plantarum 0.081 0.081 1 PMID:32913258 -4.4.1.1 o-acetyl-l-serine saccharomyces cerevisiae 0.0097 0.0097 1 PMID:24291053 -4.4.1.11 d-methionine porphyromonas gingivalis 0.019 0.019 1 PMID:33746063 -4.4.1.11 dl-homocysteine citrobacter freundii 8.51 8.5 5 PMID:15901718;PMID:16615855;PMID:20146062;PMID:21166645 -4.4.1.11 dl-homocysteine entamoeba histolytica 10.56 3.91 5 PMID:18199285;PMID:20146062 -4.4.1.11 dl-homocysteine pseudomonas putida 71.0 44.84 3 PMID:18603802;PMID:20146062;PMID:22785484 -4.4.1.11 dl-homoserine citrobacter freundii 0.52 0.51 2 PMID:16615855;PMID:21166645 -4.4.1.11 dl-methionine porphyromonas gingivalis 2.42 2.42 1 PMID:33746063 -4.4.1.11 l-cysteine citrobacter freundii 2.33 2.3 3 PMID:15901718;PMID:16615855 -4.4.1.11 l-cysteine entamoeba histolytica 1.59 1.59 3 PMID:18199285;PMID:20146062 -4.4.1.11 l-cysteine fusobacterium nucleatum subsp. nucleatum 0.69 0.69 1 PMID:21798982 -4.4.1.11 l-cysteine porphyromonas gingivalis 1.86 1.86 1 PMID:21798982 -4.4.1.11 l-cysteine pseudomonas putida 2.27 2.27 3 PMID:18603802;PMID:20146062;PMID:22785484 -4.4.1.11 l-cysteine pseudomonas sp. 34.9 34.9 1 PMID:37305655 -4.4.1.11 l-cysteine streptomyces avermitilis 0.03 0.03 1 PMID:25817696 -4.4.1.11 l-cysteine treponema denticola 0.79 0.79 1 PMID:21798982 -4.4.1.11 l-ethionine citrobacter freundii 6.78 6.2 3 PMID:15901718;PMID:20146062 -4.4.1.11 l-ethionine porphyromonas gingivalis 7.58 7.58 1 PMID:33746063 -4.4.1.11 l-ethionine pseudomonas putida 33.4 16.7085 2 PMID:11193400 -4.4.1.11 l-gly(vinyl) citrobacter freundii 1.9 1.9 1 PMID:16615855 -4.4.1.11 l-homocysteine streptomyces avermitilis 1.7 1.7 1 PMID:25817696 -4.4.1.11 l-homoserine porphyromonas gingivalis 1.06 1.06 1 PMID:33746063 -4.4.1.11 l-homoserine pseudomonas putida 1.4 1.4 1 PMID:20146062 -4.4.1.11 l-homoserine lactone porphyromonas gingivalis 0.25 0.25 1 PMID:33746063 -4.4.1.11 l-methionine citrobacter freundii 7.9 6.35 6 PMID:15901718;PMID:16615855;PMID:20146062;PMID:21166645;PMID:30268810 -4.4.1.11 l-methionine clostridium sporogenes 9.86 9.86 1 PMID:24303205 -4.4.1.11 l-methionine clostridium tetani 12.0 12.0 1 PMID:24303205 -4.4.1.11 l-methionine entamoeba histolytica 1.82 1.82 3 PMID:18199285;PMID:20146062 -4.4.1.11 l-methionine micromonospora echinospora 0.1 0.1 1 PMID:25404066 -4.4.1.11 l-methionine porphyromonas gingivalis 5.52 5.47 3 PMID:24303205;PMID:27235171;PMID:33746063 -4.4.1.11 l-methionine pseudomonas putida 48.6 29.395 4 PMID:11193400;PMID:18603802;PMID:22785484 -4.4.1.11 l-methionine pseudomonas sp. 53.1 53.1 1 PMID:37305655 -4.4.1.11 l-methionine streptomyces avermitilis 2.9 2.9 1 PMID:25817696 -4.4.1.11 l-methionine sulfone citrobacter freundii 2.1 2.1 1 PMID:21166645 -4.4.1.11 l-methionine sulfone porphyromonas gingivalis 34.13 30.715000000000003 2 PMID:27235171;PMID:33746063 -4.4.1.11 l-methionine sulfone pseudomonas putida 40.4 40.4 1 PMID:11193400 -4.4.1.11 l-methionine sulfoxide citrobacter freundii 2.52 2.51 2 PMID:21166645;PMID:31711941 -4.4.1.11 l-methionine sulfoxide clostridium sporogenes 6.7 6.7 1 PMID:24303205 -4.4.1.11 l-methionine sulfoxide clostridium tetani 2.7 2.7 1 PMID:24303205 -4.4.1.11 l-methionine sulfoxide porphyromonas gingivalis 5.05 5.05 1 PMID:24303205 -4.4.1.11 l-vinylglycine citrobacter freundii 1.9 1.9 1 PMID:21166645 -4.4.1.11 l-vinylglycine porphyromonas gingivalis 24.47 24.47 1 PMID:33746063 -4.4.1.11 l-vinylglycine pseudomonas putida 44.4 44.4 1 PMID:11193400 -4.4.1.11 o-acetyl-dl-homoserine citrobacter freundii 2.1 2.1 1 PMID:21166645 -4.4.1.11 o-acetyl-l-homoserine pseudomonas putida 78.0 78.0 1 PMID:11193400 -4.4.1.11 o-acetyl-l-serine entamoeba histolytica 6.22 3.98 2 PMID:18199285 -4.4.1.11 s-benzyl-l-cysteine citrobacter freundii 10.9 8.18 4 PMID:15901718;PMID:16615855;PMID:31711941 -4.4.1.11 s-benzyl-l-cysteine clostridium sporogenes 10.0 10.0 1 PMID:24303205 -4.4.1.11 s-benzyl-l-cysteine clostridium tetani 8.5 8.5 1 PMID:24303205 -4.4.1.11 s-benzyl-l-cysteine porphyromonas gingivalis 5.8 5.8 1 PMID:24303205 -4.4.1.11 s-butyl-l-cysteine citrobacter freundii 6.2 6.2 1 PMID:31711941 -4.4.1.11 s-ethyl-l-cysteine citrobacter freundii 6.8 5.03 3 PMID:15901718;PMID:16615855 -4.4.1.11 s-ethyl-l-cysteine clostridium sporogenes 6.3 6.3 1 PMID:24303205 -4.4.1.11 s-ethyl-l-cysteine clostridium tetani 7.08 7.08 1 PMID:24303205 -4.4.1.11 s-ethyl-l-cysteine porphyromonas gingivalis 8.05 8.05 1 PMID:24303205 -4.4.1.11 s-ethyl-l-cysteine pseudomonas putida 5.79 5.79 1 PMID:11193400 -4.4.1.11 s-ethyl-l-homocysteine citrobacter freundii 6.8 6.8 1 PMID:16615855 -4.4.1.11 s-ethyl-l-homocysteine clostridium sporogenes 7.05 7.05 1 PMID:24303205 -4.4.1.11 s-ethyl-l-homocysteine clostridium tetani 5.89 5.89 1 PMID:24303205 -4.4.1.11 s-ethyl-l-homocysteine porphyromonas gingivalis 3.84 3.84 1 PMID:24303205 -4.4.1.11 s-ethyl-l-homocysteine sulfoxide citrobacter freundii 1.85 1.85 1 PMID:31711941 -4.4.1.11 s-methyl-l-cysteine citrobacter freundii 5.97 5.25 4 PMID:15901718;PMID:16615855;PMID:20146062 -4.4.1.11 s-methyl-l-cysteine pseudomonas putida 5.53 3.555 2 PMID:11193400;PMID:22785484 -4.4.1.11 trifluoromethionine entamoeba histolytica 17.46 0.89 4 PMID:18199285;PMID:20146062 -4.4.1.13 cystathionine candidatus pelagibacter communis 1.0 1.0 1 PMID:28640457 -4.4.1.13 cystathionine mimosa pudica 21000.0 21000.0 1 PMID:31368041 -4.4.1.13 cystathionine salmonella enterica 1.5 1.5 1 PMID:15155634 -4.4.1.13 cystathionine thermotoga maritima 9.2 3.3 3 PMID:28640457 -4.4.1.13 cystathionine wolbachia pipientis 0.0011 0.0011 1 PMID:28640457 -4.4.1.13 l-cystathionine escherichia coli 54.5 45.3 3 PMID:20014435;PMID:23470500;PMID:23969077 -4.4.1.13 l-cystathionine saccharomyces cerevisiae 0.91 0.91 1 PMID:21478306 -4.4.1.13 l-cysteine latilactobacillus sakei 930.0 930.0 1 PMID:29563907 -4.4.1.13 l-djenkolate saccharomyces cerevisiae 1.27 1.27 1 PMID:21478306 -4.4.1.14 (r,s)-s-adenosyl-l-methionine malus domestica 0.079 0.079 1 PMID:14678788 -4.4.1.14 (r,s)-s-adenosylmethionine malus domestica 0.079 0.079 1 PMID:11591146 -4.4.1.14 (s,s)-s-adenosyl-l-methionine malus domestica 9.2 9.2 1 PMID:14678788 -4.4.1.14 (s,s)-s-adenosylmethionine malus domestica 18.0 18.0 1 PMID:11591146 -4.4.1.14 alanine malus domestica 0.019 0.019 1 PMID:11591146 -4.4.1.14 l-alanine malus domestica 0.0029 0.0027 2 PMID:11106504;PMID:14678788 -4.4.1.14 l-arginine malus domestica 0.0012 0.0012 1 PMID:11106504 -4.4.1.14 l-vinylglycine malus domestica 1.8 1.0 5 PMID:11106504;PMID:11591146;PMID:14678788 -4.4.1.14 s-adenosyl-l-methionine malus domestica 9.2 9.2 1 PMID:11106504 -4.4.1.14 s-adenosyl-l-methionine penicillium citrinum 0.75 0.75 1 PMID:11515533 -4.4.1.14 s-adenosyl-l-methionine solanum lycopersicum 9.79 2.1 3 PMID:10557240;PMID:15983009 -4.4.1.14 s-methyl-l-methionine malus domestica 0.045 0.0016 3 PMID:14678788 -4.4.1.15 3-chloro-d-alanine escherichia coli 281.0 281.0 1 PMID:11527960 -4.4.1.15 d-cysteine arabidopsis thaliana 6.0 6.0 1 PMID:15720402 -4.4.1.15 d-cysteine escherichia coli 72.0 72.0 1 PMID:11527960 -4.4.1.15 d-cysteine methylorubrum extorquens 5.2 5.2 1 PMID:29520528 -4.4.1.15 d-cysteine solanum lycopersicum 13800.0 13800.0 1 PMID:18825405 -4.4.1.16 l-cysteine sulfinate mus musculus 0.35 0.35 1 PMID:10692412;PMID:11898407 -4.4.1.16 l-selenocysteine enterococcus faecalis 4.43 4.43 1 PMID:33444662 -4.4.1.16 l-selenocysteine leuconostoc mesenteroides 1.8 1.8 1 PMID:35122135 -4.4.1.16 l-selenocysteine mus musculus 46.0 46.0 1 PMID:10692412;PMID:11898407 -4.4.1.2 l-cysteine aspergillus fumigatus 0.00077 0.00077 1 PMID:23568204 -4.4.1.2 l-homocysteine aspergillus fumigatus 0.00139 0.00139 1 PMID:23568204 -4.4.1.2 l-methionine aspergillus fumigatus 0.00097 0.00097 1 PMID:23568204 -4.4.1.20 glutathione homo sapiens 26.0 2.22 5 PMID:21454538;PMID:24366866;PMID:27365393 -4.4.1.20 glutathione mus musculus 84.0 84.0 1 PMID:24810165 -4.4.1.20 leukotriene a4 homo sapiens 105.0 12.0 3 PMID:20980252;PMID:24366866;PMID:27365393 -4.4.1.20 leukotriene a4 mus musculus 81.0 81.0 1 PMID:24810165 -4.4.1.20 leukotriene a4 methyl ester homo sapiens 2.1 1.97 3 PMID:21454538 -4.4.1.21 (2r)-2-amino-4-[[(2s,4s)-2,4,5-trihydroxy-3-oxopentyl]sulfanyl]butanoic acid bacillus subtilis 0.038 0.038 1 PMID:19099445 -4.4.1.21 (2r)-2-amino-4-[[(2s,4s)-2,4,5-trihydroxy-3-oxopentyl]sulfanyl]butanoic acid escherichia coli 0.4 0.4 1 PMID:19099445 -4.4.1.21 (2r)-2-amino-4-[[(2s,4s)-2,4,5-trihydroxy-3-oxopentyl]sulfanyl]butanoic acid vibrio harveyi 0.64 0.64 1 PMID:19099445 -4.4.1.21 s-ribosylhomocysteine bacillus subtilis 0.03 0.03 2 PMID:15751951;PMID:19099445 -4.4.1.21 s-ribosylhomocysteine escherichia coli 0.4 0.4 1 PMID:19099445 -4.4.1.21 s-ribosylhomocysteine lactiplantibacillus plantarum 0.47 0.405 2 PMID:29305177 -4.4.1.21 s-ribosylhomocysteine streptococcus suis 0.102 0.102 1 PMID:26484864 -4.4.1.21 s-ribosylhomocysteine vibrio harveyi 0.4 0.4 1 PMID:19099445 -4.4.1.23 epoxypropane xanthobacter autotrophicus 6.5 6.5 1 PMID:11939797 -4.4.1.28 beta-chloro-l-alanine treponema denticola 14.5 14.5 1 PMID:10495709 -4.4.1.28 l-cystathionine lactobacillus delbrueckii subsp. bulgaricus 11.0 11.0 1 PMID:28003427 -4.4.1.28 l-cysteine lactobacillus delbrueckii subsp. bulgaricus 2.9 2.9 1 PMID:28003427 -4.4.1.28 l-cysteine methanocaldococcus jannaschii 39.6 39.6 1 PMID:15683250 -4.4.1.28 l-cysteine treponema denticola 12.0 10.9 3 PMID:10194060;PMID:10495709 -4.4.1.28 l-cysteine methyl ester treponema denticola 32.0 32.0 1 PMID:10495709 -4.4.1.28 l-cystine lactobacillus delbrueckii subsp. bulgaricus 29.0 29.0 1 PMID:28003427 -4.4.1.28 l-djenkolic acid lactobacillus delbrueckii subsp. bulgaricus 19.0 19.0 1 PMID:28003427 -4.4.1.28 s-(2-methyl-4-oxopentan-2-yl)-l-cysteine lactobacillus delbrueckii subsp. bulgaricus 4.0 4.0 1 PMID:28003427 -4.4.1.28 s-aminoethyl-l-cysteine lactobacillus delbrueckii subsp. bulgaricus 17.8 17.8 1 PMID:28003427 -4.4.1.28 s-ethyl-l-cysteine treponema denticola 9.5 9.5 1 PMID:10495709 -4.4.1.28 s-methyl-l-cysteine treponema denticola 5.95 5.95 1 PMID:10495709 -4.4.1.29 (2r,3e)-phycocyanobilin anabaena sp. 2.5e-05 2.5e-05 1 PMID:19864423 -4.4.1.29 apo-[allophycocyanin alpha-subunit] anabaena sp. 0.0027 0.0027 1 PMID:17726096 -4.4.1.29 apo-[allophycocyanin beta-subunit] anabaena sp. 0.0024 0.0024 1 PMID:17726096 -4.4.1.3 3-(thiolan-1-ium-1-yl)propanoate phaeobacter inhibens 2.04 2.04 1 PMID:28485454 -4.4.1.3 3-(thiolan-1-ium-1-yl)propanoate ruegeria pomeroyi 21.9 11.739999999999998 2 PMID:28485454 -4.4.1.3 beta-dimethylsulfoniopropanoate acinetobacter bereziniae 8300.0 8300.0 1 PMID:29106934 -4.4.1.3 beta-dimethylsulfoniopropanoate alcaligenes faecalis 900.0 900.0 1 PMID:29561599 -4.4.1.3 beta-dimethylsulfoniopropanoate halodesulfovibrio aestuarii 1130.0 1130.0 1 PMID:29561599 -4.4.1.3 beta-dimethylsulfoniopropanoate ruegeria pomeroyi 18.25 17.79 2 PMID:25993446 -4.4.1.3 diethylsulfoniopropionate phaeobacter inhibens 1.71 1.71 1 PMID:28485454 -4.4.1.3 diethylsulfoniopropionate ruegeria pomeroyi 11.9 7.0600000000000005 2 PMID:28485454 -4.4.1.3 dimethylseleniopropionate phaeobacter inhibens 4.25 4.25 1 PMID:28485454 -4.4.1.3 dimethylseleniopropionate ruegeria pomeroyi 31.2 16.515 2 PMID:28485454 -4.4.1.3 dimethylsulfoniopropionate phaeobacter inhibens 3.85 3.85 1 PMID:28485454 -4.4.1.3 dimethylsulfoniopropionate ruegeria pomeroyi 16.8 8.865 2 PMID:28485454 -4.4.1.3 dimethylsulfoxonium propionate celeribacter halophilus 2.0 2.0 1 PMID:3694339 -4.4.1.3 dimethylsulfoxonium propionate ferrimonas balearica 53.7 53.7 1 PMID:3694339 -4.4.1.3 dimethylsulfoxonium propionate ruegeria pomeroyi 49.0 7.4 3 PMID:3694339 -4.4.1.3 ethylmethylsulfoniopropionate phaeobacter inhibens 2.07 2.07 1 PMID:28485454 -4.4.1.3 ethylmethylsulfoniopropionate ruegeria pomeroyi 11.5 6.485 2 PMID:28485454 -4.4.1.3 methylpropylsulfoniopropionate phaeobacter inhibens 1.67 1.67 1 PMID:28485454 -4.4.1.3 methylpropylsulfoniopropionate ruegeria pomeroyi 10.9 7.315 2 PMID:28485454 -4.4.1.3 s,s-dimethyl-beta-propiothetin acinetobacter bereziniae 8.3 8.3 1 PMID:3694339 -4.4.1.3 s,s-dimethyl-beta-propiothetin candidatus pelagibacter communis 2.1 1.5 2 PMID:3694339 -4.4.1.3 s,s-dimethyl-beta-propiothetin celeribacter halophilus 1.45 1.45 1 PMID:3694339 -4.4.1.3 s,s-dimethyl-beta-propiothetin ferrimonas balearica 4.94 4.94 1 PMID:3694339 -4.4.1.3 s,s-dimethyl-beta-propiothetin phaeobacter inhibens 0.7 0.7 1 PMID:36808192 -4.4.1.3 s,s-dimethyl-beta-propiothetin ruegeria lacuscaerulensis 1.011 1.011 1 PMID:3694339 -4.4.1.3 s,s-dimethyl-beta-propiothetin ruegeria pomeroyi 41.0 4.65 5 PMID:3694339 -4.4.1.31 (2r,3e)-phycocyanobilin mastigocladus laminosus 7.4e-05 7.4e-05 1 PMID:12230566 -4.4.1.31 apo-[phycoerythrocyanin alpha-subunit] mastigocladus laminosus 0.00013 0.00013 1 PMID:12230566 -4.4.1.31 phycocyanobilin mastigocladus laminosus 2.1e-05 2.1e-05 1 PMID:15924432 -4.4.1.32 (2r,3e)-phycocyanobilin synechococcus elongatus 0.025 0.025 1 PMID:8132596 -4.4.1.36 (2r)-3-(2-[[(2r)-2-amino-2-carboxyethyl]sulfanyl]-2,3-dihydro-1h-imidazol-4-yl)-2-(trimethylazaniumyl)propanoate mycolicibacterium smegmatis 7.9 7.9 1 PMID:26149121 -4.4.1.36 s-(hercyn-2-yl)-l-cysteine s-oxide mycolicibacterium smegmatis 25.3 25.3 1 PMID:26149121 -4.4.1.38 2-hydroxyethane-1-sulfonate bilophila wadsworthia 14.0 14.0 1 PMID:30718429 -4.4.1.38 isethionate bilophila wadsworthia 9.5 9.5 1 PMID:33773110 -4.4.1.38 isethionate nitratidesulfovibrio vulgaris 91.6 91.6 1 PMID:30962433 -4.4.1.4 (+)-alliin allium sativum 193.0 193.0 1 PMID:33740023 -4.4.1.4 (+/-)-alliin allium sativum 0.015 0.0115 2 PMID:22374998 -4.4.1.4 (2r)-2-amino-3-(1-phenylethylsulfinyl)propanoic acid petiveria alliacea 8.18 8.18 1 PMID:19789290 -4.4.1.4 (2r)-2-amino-3-(2-methylbenzylsulfinyl)propanoic acid petiveria alliacea 14.33 14.33 1 PMID:19789290 -4.4.1.4 (2r)-2-amino-3-(4-chlorobenzylsulfinyl)propanoic acid petiveria alliacea 10.65 10.65 1 PMID:19789290 -4.4.1.4 (2r)-2-amino-3-(4-methylbenzylsulfinyl)propanoic acid petiveria alliacea 2.67 2.67 1 PMID:19789290 -4.4.1.4 (2r)-2-amino-3-(ethylsulfinyl)propanoic acid petiveria alliacea 2.48 2.48 1 PMID:19789290 -4.4.1.4 (2r)-2-amino-3-(phenethylsulfinyl)propanoic acid petiveria alliacea 1.75 1.75 1 PMID:19789290 -4.4.1.4 (2r)-2-amino-3-(phenylsulfinyl)propanoic acid petiveria alliacea 6.48 6.48 1 PMID:19789290 -4.4.1.4 2-hydroxyethiin petiveria alliacea 4.2 4.2 1 PMID:19789290 -4.4.1.4 4-mercaptopyridine allium sativum 0.0028 0.002325 2 PMID:22374998 -4.4.1.4 alliin petiveria alliacea 20.67 20.67 1 PMID:19789290 -4.4.1.4 methiin petiveria alliacea 15.1 15.1 1 PMID:19789290 -4.4.1.4 petiveriin petiveria alliacea 4.47 4.47 1 PMID:19789290 -4.4.1.4 propiin petiveria alliacea 1.96 1.96 1 PMID:19789290 -4.4.1.41 (2s)-2,3-dihydroxypropane-1-sulfonate bilophila wadsworthia 26.0 26.0 1 PMID:32571930 -4.4.1.43 l-canavanine pseudomonas alvandae 1.34 1.34 1 PMID:36320885 -4.4.1.5 (r)-s-lactoylglutathione oryza sativa japonica group 70.96 70.96 1 PMID:24661284 -4.4.1.5 glutathione homo sapiens 1360.0 1360.0 1 PMID:16430697 -4.4.1.5 glutathione saccharomyces cerevisiae 258.3 258.3 1 PMID:21591178 -4.4.1.5 glutathione ethyl ester homo sapiens 164.0 164.0 1 PMID:16430697 -4.4.1.5 glutathione isopropyl ester homo sapiens 222.0 222.0 1 PMID:16430697 -4.4.1.5 glutathione isopropyl ester leishmania major 1170.0 1170.0 1 PMID:16430697 -4.4.1.5 glutathione-methylglyoxal hemithioacetal escherichia coli 338.0 57.95 8 PMID:14556652;PMID:9628737 -4.4.1.5 glutathione-methylglyoxal hemithioacetal homo sapiens 1820.0 1820.0 1 PMID:8489699 -4.4.1.5 glutathione-methylglyoxal hemithioacetal plasmodium falciparum 66.7 66.7 1 PMID:14623080 -4.4.1.5 glutathione-methylglyoxal hemithioacetal saccharomyces cerevisiae 1700.0 1700.0 1 PMID:11050082 -4.4.1.5 glutathionylspermidine trypanosoma cruzi 161.0 133.0 2 PMID:16958620 -4.4.1.5 methylglyoxal homo sapiens 1130.0 1109.0 2 PMID:24856185;PMID:393249;PMID:7154966 -4.4.1.5 methylglyoxal neisseria meningitidis 204.0 175.0 2 PMID:15270717 -4.4.1.5 methylglyoxal onchocerca volvulus 11.4 11.4 1 PMID:11171039 -4.4.1.5 methylglyoxal pseudomonas aeruginosa 271.0 178.5 2 PMID:15270717 -4.4.1.5 methylglyoxal rattus norvegicus 1180.0 1180.0 1 PMID:393249;PMID:6173571 -4.4.1.5 methylglyoxal saccharomyces cerevisiae 1820.0 1820.0 1 PMID:393249 -4.4.1.5 methylglyoxal sus scrofa 983.0 983.0 1 PMID:393249 -4.4.1.5 methylglyoxal yersinia pestis 306.0 187.5 2 PMID:15270717 -4.4.1.5 n-[3-[(4-aminobutyl)amino]propyl]-l-gamma-glutamyl-l-cysteinylglycine homo sapiens 83.0 83.0 1 PMID:16430697 -4.4.1.5 n-[3-[(4-aminobutyl)amino]propyl]-l-gamma-glutamyl-l-cysteinylglycine leishmania major 1590.0 1590.0 1 PMID:16430697 -4.4.1.5 phenylglyoxal homo sapiens 1070.0 1070.0 1 PMID:393249;PMID:7154966 -4.4.1.5 phenylglyoxal onchocerca volvulus 81.7 41.115 2 PMID:11171039 -4.4.1.5 phenylglyoxal rattus norvegicus 1100.0 1100.0 1 PMID:393249;PMID:6173571 -4.4.1.5 phenylglyoxal saccharomyces cerevisiae 6700.0 6700.0 1 PMID:393249 -4.4.1.5 phenylglyoxal sus scrofa 617.0 617.0 1 PMID:393249 -4.4.1.5 trypanothione homo sapiens 104.0 104.0 1 PMID:16430697 -4.4.1.5 trypanothione leishmania major 1070.0 1070.0 1 PMID:16430697 -4.4.1.5 trypanothione trypanosoma cruzi 363.0 314.0 2 PMID:16958620 -4.4.1.9 hydrogen cyanide glycine max 39.2 39.2 1 PMID:22739827 -4.4.1.9 hydrogen sulfide pieris rapae 10.25 5.34 2 PMID:26714205 -4.4.1.9 kcn arabidopsis thaliana 2.94 2.5549999999999997 2 PMID:10845460 -4.4.1.9 l-cysteine arabidopsis thaliana 6.0 4.335 2 PMID:10845460 -4.4.1.9 l-cysteine glycine max 38.9 38.9 1 PMID:22739827 -4.4.1.9 l-cysteine pieris rapae 7.49 1.69 3 PMID:26714205 -4.4.1.9 l-cysteine tetranychus urticae 2135.0 2135.0 1 PMID:24843024 -4.4.1.9 na2s arabidopsis thaliana 1.5 1.5 1 PMID:10845460 -4.4.1.9 o-acetyl-l-serine arabidopsis thaliana 2.0 2.0 1 PMID:10845460 -4.5.1.1 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane musca domestica 0.0383 0.0383 1 PMID:13673024 -4.5.1.1 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane pseudomonas putida 0.113 0.113 1 PMID:22239708 -4.5.1.3 bromomethane methylophilus sp. 0.14 0.14 1 PMID:12974641 -4.5.1.3 ch2brcl methylophilus sp. 1.0 1.0 1 PMID:12974641 -4.5.1.3 ch2clf methylophilus sp. 0.009 0.009 1 PMID:12974641 -4.5.1.3 ch2cli methylophilus sp. 1.03 1.03 1 PMID:12974641 -4.5.1.3 chloroethane methylophilus sp. 0.1 0.1 1 PMID:12974641 -4.5.1.3 dibromomethane methylophilus sp. 5.6 3.9000000000000004 6 PMID:12974641;PMID:8706748 -4.5.1.3 dichloromethane hyphomicrobium sp. 0.6 0.575 2 PMID:3142855;PMID:9299530 -4.5.1.3 dichloromethane hyphomicrobium sp. dm2 0.55 0.55 1 PMID:17687552 -4.5.1.3 dichloromethane methylobacterium sp. 3.28 3.28 1 PMID:17687552 -4.5.1.3 dichloromethane methylophilus sp. 3.6 2.8 10 PMID:12974641;PMID:3142855;PMID:8706748;PMID:9299530 -4.5.1.3 dichloromethane methylorubrum extorquens 0.87 0.735 2 PMID:3142855;PMID:9299530 -4.5.1.3 dichloromethane methylorubrum extorquens dm4 0.87 0.87 1 PMID:17687552 -4.5.1.3 dichloromethane niallia circulans 4.78 4.04 2 PMID:17687552 -4.5.1.3 diiodomethane methylophilus sp. 1.31 1.31 1 PMID:12974641 -4.5.1.3 iodoethane methylophilus sp. 0.15 0.15 1 PMID:12974641 -4.6.1.1 atp bordetella pertussis 4600.0 1180.0 5 PMID:1693922;PMID:24907274;PMID:2867778;PMID:33499260 -4.6.1.1 atp bos taurus 1.33 1.33 1 PMID:4041438 -4.6.1.1 atp escherichia coli 1.67 1.67 1 PMID:6300054 -4.6.1.1 atp glutamicibacter nicotianae 1.67 1.67 1 PMID:6300054 -4.6.1.1 atp haloactinopolyspora alba 46.55 46.55 1 * -4.6.1.1 atp mammalia 12.0 12.0 1 PMID:8663304 -4.6.1.1 atp rattus norvegicus 34.0 12.15 4 PMID:10427002;PMID:1851925;PMID:7225326 -4.6.1.1 atp synechocystis sp. 0.00045 0.000375 2 PMID:16573521 -4.6.1.1 atp thermobifida halotolerans 27.61 27.61 1 * -4.6.1.1 atp yersinia pestis 0.889 0.3731 8 PMID:21094652 -4.6.1.12 2-phospho-4-(cytidine 5'-diphospho)-2-c-methyl-d-erythritol arabidopsis thaliana 2.5 2.5 1 PMID:20480490 -4.6.1.12 2-phospho-4-(cytidine 5'-diphospho)-2-c-methyl-d-erythritol escherichia coli 2.7 2.7 1 PMID:20480490 -4.6.1.12 2-phospho-4-(cytidine 5'-diphospho)-2-c-methyl-d-erythritol mycobacterium tuberculosis 1.8 1.8 1 PMID:20480490 -4.6.1.13 methyl-fluorescein myo-inositol phosphate listeria monocytogenes 66.0 66.0 1 PMID:12488013 -4.6.1.14 variant-surface-glycoprotein trypanosoma brucei 27.3 14.39 2 PMID:10026218 -4.6.1.15 fad rattus norvegicus 24.1 14.46 2 PMID:11695920 -4.6.1.17 (8s)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate escherichia coli 0.0093 0.009049999999999999 2 PMID:25941396 -4.6.1.18 cyclic 2',3'-cmp rattus norvegicus 2.5 2.35 2 PMID:4710591 -4.6.1.18 cyclic 2',3'-cytidine monophosphate bos taurus 12.0 12.0 1 PMID:17192592 -4.6.1.18 cyclic 2',3'-cytidine monophosphate homo sapiens 0.36 0.36 1 PMID:16519682 -4.6.1.18 cyclic 2',3'-ump rattus norvegicus 3.7 2.4000000000000004 2 PMID:4710591 -4.6.1.18 pentacytidylic acid bos taurus 323.0 323.0 1 PMID:17192592 -4.6.1.18 poly (c) homo sapiens 13.3 13.3 1 PMID:16519682 -4.6.1.18 poly(a)-poly(u) homo sapiens 8.89 8.89 1 PMID:21408145 -4.6.1.18 poly(a)poly(u) homo sapiens 0.0019 0.0019 1 PMID:17631275 -4.6.1.18 poly(c) homo sapiens 2317.0 1158.621 2 PMID:17631275;PMID:21408145 -4.6.1.18 rna bos taurus 35.7 35.7 1 PMID:16890987 -4.6.1.18 trna gallus gallus 2.6 1.328 2 PMID:16803891 -4.6.1.19 adenosine-3'-(1-naphthyl)phosphate aspergillus oryzae 0.176 0.090915 2 PMID:6260492 -4.6.1.19 adenylyl (3'-5')uridine aspergillus oryzae 0.0543 0.0173 3 PMID:6260492 -4.6.1.19 cpu momordica charantia 12.42 12.42 1 PMID:10964705 -4.6.1.19 gpc oncorhynchus keta 2.97 2.97 1 PMID:15725660 -4.6.1.19 rna escherichia coli 0.15 0.15 1 PMID:8557629 -4.6.1.2 gtp blastocladiella emersonii 0.34 0.34 1 PMID:29799525 -4.6.1.2 gtp bos taurus 290.0 3.9 3 PMID:14981084;PMID:1673683;PMID:8527937 -4.6.1.2 gtp catenaria anguillulae 1.13 1.13 1 PMID:29799525 -4.6.1.2 gtp homo sapiens 28.7 14.424999999999999 2 PMID:19189860 -4.6.1.2 gtp mus musculus 116.0 53.5 6 PMID:21598940 -4.6.1.20 rna containing adenosine 3'-(1-naphthyl phosphate) ustilago sphaerogena 0.0852 0.0852 1 PMID:7074019 -4.6.1.20 rna containing adenosine 3'-(benzyl phosphate) ustilago sphaerogena 0.00983 0.00983 1 PMID:7074019 -4.6.1.20 rna containing adenosine 3'-(methyl phosphate) ustilago sphaerogena 0.00317 0.00317 1 PMID:7074019 -4.6.1.20 rna containing apa ustilago sphaerogena 3.33 3.33 1 PMID:7074019 -4.6.1.20 rna containing apap ustilago sphaerogena 24.3 24.3 1 PMID:7074019 -4.6.1.20 rna containing apc ustilago sphaerogena 23.8 23.8 1 PMID:7074019 -4.6.1.20 rna containing apcp ustilago sphaerogena 96.2 96.2 1 PMID:7074019 -4.6.1.20 rna containing apcpgp ustilago sphaerogena 229.0 229.0 1 PMID:7074019 -4.6.1.20 rna containing apg ustilago sphaerogena 6.33 6.33 1 PMID:7074019 -4.6.1.20 rna containing apgp ustilago sphaerogena 149.0 93.1 2 PMID:7074019 -4.6.1.20 rna containing apu ustilago sphaerogena 7.33 7.33 1 PMID:7074019 -4.6.1.20 rna containing apup ustilago sphaerogena 55.0 55.0 1 PMID:7074019 -4.6.1.20 rna containing apupg ustilago sphaerogena 141.0 141.0 1 PMID:7074019 -4.6.1.20 rna containing apupgp ustilago sphaerogena 282.0 282.0 1 PMID:7074019 -4.6.1.20 rna containing cpapgp ustilago sphaerogena 59.5 59.5 1 PMID:7074019 -4.6.1.20 rna containing upapgp ustilago sphaerogena 14.8 14.8 1 PMID:7074019 -4.6.1.21 rfa13-1 enterobacter sp. 1.9 1.9 1 PMID:31420934 -4.6.1.22 30 nt rna bacillus subtilis 0.58 0.13 3 PMID:20025672 -4.6.1.22 pre-trnaasp bacillus subtilis 0.23 0.23 1 PMID:17299131 -4.6.1.23 28 s rrna aspergillus giganteus 0.917 0.917 1 PMID:6185500 -4.6.1.23 apa aspergillus giganteus 0.00027 0.0001 5 PMID:10591106;PMID:11733014;PMID:12493839;PMID:16740124;PMID:9580156 -4.6.1.23 cpc aspergillus giganteus 5.1e-05 5.1e-05 1 PMID:18214983 -4.6.1.23 gpa aspergillus giganteus 9e-06 9e-06 1 PMID:9580156 -4.6.1.24 5'-ohgggacaguauuug-3' escherichia coli 72.0 72.0 1 PMID:18078441 -4.6.1.24 5'-pgggacaguauuug-3' escherichia coli 180.0 180.0 1 PMID:18078441 -4.6.1.24 gpa aspergillus oryzae 96.0 96.0 1 * -4.6.1.24 gpc aspergillus oryzae 350.0 350.0 1 * -4.6.1.24 gpg aspergillus oryzae 62.0 62.0 1 * -4.6.1.24 gpu aspergillus oryzae 38.0 38.0 1 * -4.6.1.24 poly(i) kitasatospora aureofaciens 220.0 204.5 2 PMID:15158454;PMID:16288913 -4.6.1.6 ctp bacillus anthracis 8.8 8.0 2 PMID:20521845 -4.6.1.6 ctp bordetella pertussis 0.3 0.3 1 PMID:20521845 -4.8.1.1 n5-hydroxy-l-ornithine kutzneria sp. 744 138.0 84.5 2 PMID:28628093 -4.8.1.2 (e/z)-acetaldoxime pseudomonas chlororaphis 336.0 336.0 1 PMID:12773527 -4.8.1.2 (e/z)-n-butyraldoxime pseudomonas chlororaphis 324.0 324.0 1 PMID:12773527 -4.8.1.2 (e/z)-pyridine-2-aldoxime pseudomonas chlororaphis 5.4 5.4 1 PMID:12773527 -4.8.1.2 (z)-phenylacetaldoxime rhodococcus erythropolis 47.3 47.3 1 PMID:19740758 -4.8.1.2 5-nitro-1,2-benzoxazole bacillus sp. oxb-1 9.58 4.86 2 PMID:28120515 -4.8.1.2 5-nitro-1,2-benzoxazole pseudomonas chlororaphis 9.97 5.075 2 PMID:28120515 -4.8.1.2 5-nitro-1,2-benzoxazole rhodococcus sp. n-771 17.03 8.555 2 PMID:28120515 -4.8.1.3 (e,z)-indolyl-3-acetaldoxime sclerotinia sclerotiorum 10.0 10.0 1 PMID:21036375 -4.8.1.4 3-pyridine aldoxime pseudomonas putida 0.873 0.873 1 PMID:34489036 -4.98.1.1 co2+ bacillus subtilis 0.016 0.016 2 PMID:21052751 -4.98.1.1 cu2+ bacillus subtilis 0.065 0.065 2 PMID:21052751 -4.98.1.1 fe2+ bacillus subtilis 0.055 0.0305 4 PMID:15300829 -4.98.1.1 fe2+ bdellovibrio bacteriovorus 0.073 0.073 1 PMID:16548850 -4.98.1.1 fe2+ caulobacter vibrioides 0.267 0.267 1 PMID:16548850 -4.98.1.1 fe2+ homo sapiens 0.1 0.059000000000000004 2 PMID:17566985;PMID:17884090 -4.98.1.1 fe2+ mus musculus 0.068 0.068 1 PMID:14981080 -4.98.1.1 fe2+ myxococcus xanthus 0.08167 0.08167 1 PMID:16548850 -4.98.1.1 fe2+ pseudomonas putida 0.195 0.195 1 PMID:16548850 -4.98.1.1 hemin sus scrofa 0.52 0.52 1 PMID:20622448 -4.98.1.1 mesoporphyrin ix sus scrofa 6.7 6.7 1 PMID:20622448 -4.98.1.1 porphyrin homo sapiens 0.0573 0.0573 1 PMID:17567154 -4.98.1.1 protoporphyrin bacillus subtilis 0.483 0.483 1 PMID:8119288 -4.98.1.1 protoporphyrin vibrio vulnificus 1.53 1.52 2 PMID:30251658 -4.98.1.1 protoporphyrin ix mus musculus 0.0683 0.068 3 PMID:14981080;PMID:16503645;PMID:16792525 -4.98.1.1 protoporphyrin ix mycobacterium tuberculosis 0.013 0.013 1 PMID:25646457 -4.98.1.1 protoporphyrin ix rattus norvegicus 0.142 0.07725 2 PMID:21222436 -4.98.1.1 protoporphyrin ix synechocystis sp. 0.052 0.052 1 PMID:23390541 -4.98.1.1 zn2+ homo sapiens 3.5 3.35 2 PMID:19767646 -4.98.1.1 zn2+ sus scrofa 6.7 6.7 1 PMID:20622448 -4.98.1.1 zn2+ synechocystis sp. 0.034 0.034 1 PMID:23390541 -4.99.1.11 ni2+ methanocaldococcus jannaschii 0.0055 0.0055 1 PMID:34163982 -4.99.1.11 sirohydrochlorin methanocaldococcus jannaschii 0.0055 0.0055 1 PMID:34163982 -4.99.1.2 cis-2-butenyl mercuric chloride escherichia coli 4.0 4.0 1 * -4.99.1.2 methyl mercuric chloride escherichia coli 0.0167 0.0167 1 * -4.99.1.2 n-butyl mercurial escherichia coli 0.333 0.333 1 * -4.99.1.2 tetravinyltin escherichia coli 0.00333 0.00333 1 * -4.99.1.3 co2+ methanocaldococcus jannaschii 0.06 0.06 1 PMID:34163982 -4.99.1.3 sirohydrochlorin methanocaldococcus jannaschii 0.06 0.06 1 PMID:34163982 -4.99.1.4 co2+ methanocaldococcus jannaschii 0.06 0.06 1 PMID:34163982 -4.99.1.4 sirohydrochlorin methanocaldococcus jannaschii 0.06 0.06 1 PMID:34163982 -4.99.1.9 coproporphyrin iii bacillus subtilis 0.0078 0.0078 1 PMID:25646457 -4.99.1.9 coproporphyrin iii mycobacterium tuberculosis 0.03 0.03 1 PMID:25646457 -4.99.1.9 fe2+ listeria monocytogenes 0.132 0.132 1 PMID:31794133 -4.99.1.9 protoporphyrin ix bacillus subtilis 0.4 0.4 1 PMID:8119288 -5.1.1.1 d-ala aquifex pyrophilus 24.8 24.8 1 * -5.1.1.1 d-ala geobacillus stearothermophilus 7.0 7.0 1 PMID:3291946 -5.1.1.1 d-ala penaeus monodon 2314.0 2314.0 1 PMID:12431412 -5.1.1.1 d-ala procambarus clarkii 3272.0 3271.0 2 PMID:11026672 -5.1.1.1 d-ala salmonella enterica subsp. enterica serovar typhimurium 2.6 2.1 2 PMID:3291946 -5.1.1.1 d-alanine caldanaerobacter subterraneus subsp. tengcongensis 96.9 96.9 1 PMID:26218070 -5.1.1.1 d-alanine clostridioides difficile 19.25 19.25 1 PMID:25004969 -5.1.1.1 d-alanine escherichia coli 8.0 5.525 10 PMID:15796715;PMID:18434499 -5.1.1.1 d-alanine geobacillus stearothermophilus 1017.0 1017.0 1 PMID:23035128 -5.1.1.1 d-alanine helicobacter pylori 37.9 37.9 1 PMID:17196222 -5.1.1.1 d-alanine streptomyces lavendulae 70.0 66.65 2 PMID:15302885;PMID:15796715 -5.1.1.1 d-alanine synechocystis sp. pcc 6803 4.42 4.42 1 PMID:34967408 -5.1.1.1 d-alanine tolypocladium inflatum 0.06 0.06 1 PMID:23219598 -5.1.1.1 d-serine streptomyces lavendulae 5.5 5.5 1 PMID:15796715 -5.1.1.1 l-ala geobacillus stearothermophilus 1.1 1.1 1 PMID:3291946 -5.1.1.1 l-ala penaeus monodon 2589.0 2589.0 1 PMID:12431412 -5.1.1.1 l-ala procambarus clarkii 7504.0 7502.0 2 PMID:11026672 -5.1.1.1 l-ala salmonella enterica subsp. enterica serovar typhimurium 9.7 8.5 2 PMID:3291946 -5.1.1.1 l-alanine bacillus anthracis 22.0 22.0 1 PMID:19192393 -5.1.1.1 l-alanine bacillus subtilis 1190.0 1190.0 1 PMID:27480853 -5.1.1.1 l-alanine caldanaerobacter subterraneus subsp. tengcongensis 212.4 212.4 1 PMID:26218070 -5.1.1.1 l-alanine candidatus pelagibacter communis 0.15 0.15 1 PMID:28640457 -5.1.1.1 l-alanine clostridioides difficile 59.3 59.3 1 PMID:25004969 -5.1.1.1 l-alanine clostridium perfringens 17.2 17.2 1 PMID:30826314 -5.1.1.1 l-alanine escherichia coli 70.92 46.795 10 PMID:15796715;PMID:18434499 -5.1.1.1 l-alanine geobacillus stearothermophilus 1533.0 1533.0 1 PMID:23035128 -5.1.1.1 l-alanine helicobacter pylori 632.0 632.0 1 PMID:17196222 -5.1.1.1 l-alanine mycobacterium tuberculosis 37.0 37.0 1 PMID:27480853 -5.1.1.1 l-alanine pseudomonas putida 70.63 70.63 1 PMID:22806802 -5.1.1.1 l-alanine streptomyces lavendulae 55.0 55.0 2 PMID:15302885;PMID:15796715 -5.1.1.1 l-alanine thermotoga maritima 0.022 0.0065 3 PMID:28640457 -5.1.1.1 l-alanine tolypocladium inflatum 0.9 0.9 1 PMID:23219598 -5.1.1.1 l-alanine wolbachia pipientis 2.3 2.3 1 PMID:28640457 -5.1.1.1 l-serine streptomyces lavendulae 13.3 13.3 1 PMID:15796715 -5.1.1.10 d-alanine latilactobacillus sakei 1830.0 1830.0 1 PMID:29563907 -5.1.1.10 d-leucine thermococcus kodakarensis 108.0 108.0 1 PMID:33468590 -5.1.1.10 d-leucine thermococcus litoralis 0.79 0.79 1 PMID:33942867 -5.1.1.10 d-lysine bacillus subtilis 0.0037 0.0037 1 PMID:28894939 -5.1.1.10 d-methionine thermococcus kodakarensis 86.0 86.0 1 PMID:33468590 -5.1.1.10 d-methionine thermococcus litoralis 1.8 1.8 1 PMID:33942867 -5.1.1.10 d-ornithine pseudomonas putida 325.0 193.5 4 PMID:32492177 -5.1.1.10 d-serine mus musculus 14.5 14.5 1 PMID:16185077 -5.1.1.10 l-alanine latilactobacillus sakei 2310.0 2310.0 1 PMID:29563907 -5.1.1.10 l-leucine thermococcus kodakarensis 43.3 43.3 1 PMID:33468590 -5.1.1.10 l-leucine thermococcus litoralis 0.62 0.62 1 PMID:33942867 -5.1.1.10 l-lysine bacillus subtilis 0.0013 0.0013 1 PMID:28894939 -5.1.1.10 l-methionine thermococcus kodakarensis 54.4 54.4 1 PMID:33468590 -5.1.1.10 l-serine mus musculus 3.8 3.8 1 PMID:16185077 -5.1.1.10 n-acetyl-d-alanine geobacillus kaustophilus 0.8 0.8 1 * -5.1.1.10 n-acetyl-d-asparagine geobacillus kaustophilus 0.07 0.07 1 * -5.1.1.10 n-acetyl-d-methionine geobacillus kaustophilus 20.0 20.0 1 * -5.1.1.10 n-acetyl-d-phenylalanine geobacillus kaustophilus 10.0 10.0 1 * -5.1.1.10 n-acetyl-d-tryptophan geobacillus kaustophilus 0.09 0.09 1 * -5.1.1.10 n-acetyl-l-alanine geobacillus kaustophilus 2.0 2.0 1 * -5.1.1.10 n-acetyl-l-asparagine geobacillus kaustophilus 0.06 0.06 1 * -5.1.1.10 n-acetyl-l-methionine geobacillus kaustophilus 22.0 22.0 1 * -5.1.1.10 n-acetyl-l-phenylalanine geobacillus kaustophilus 16.0 16.0 1 * -5.1.1.10 n-acetyl-l-tryptophan geobacillus kaustophilus 0.15 0.15 1 * -5.1.1.10 n-carbamoyl-d-methionine geobacillus kaustophilus 2.0 2.0 1 * -5.1.1.10 n-carbamoyl-l-methionine geobacillus kaustophilus 2.0 2.0 1 * -5.1.1.10 n-succinyl-d-alanine geobacillus kaustophilus 15.0 15.0 1 * -5.1.1.10 n-succinyl-d-phenylalanine geobacillus kaustophilus 2.0 2.0 1 * -5.1.1.10 n-succinyl-l-ala geobacillus kaustophilus 89.0 89.0 1 PMID:16584181 -5.1.1.10 n-succinyl-l-alanine geobacillus kaustophilus 43.0 43.0 1 * -5.1.1.10 n-succinyl-l-arg geobacillus kaustophilus 0.014 0.014 1 PMID:16584181 -5.1.1.10 n-succinyl-l-asn geobacillus kaustophilus 2.5 2.5 1 PMID:16584181 -5.1.1.10 n-succinyl-l-asp geobacillus kaustophilus 0.071 0.071 1 PMID:16584181 -5.1.1.10 n-succinyl-l-gln geobacillus kaustophilus 9.0 9.0 1 PMID:16584181 -5.1.1.10 n-succinyl-l-glu geobacillus kaustophilus 0.073 0.073 1 PMID:16584181 -5.1.1.10 n-succinyl-l-his geobacillus kaustophilus 2.0 2.0 1 PMID:16584181 -5.1.1.10 n-succinyl-l-ile geobacillus kaustophilus 35.0 35.0 1 PMID:16584181 -5.1.1.10 n-succinyl-l-leu geobacillus kaustophilus 17.0 17.0 1 PMID:16584181 -5.1.1.10 n-succinyl-l-lys geobacillus kaustophilus 2.1 2.1 1 PMID:16584181 -5.1.1.10 n-succinyl-l-met geobacillus kaustophilus 53.0 53.0 1 PMID:16584181 -5.1.1.10 n-succinyl-l-phe geobacillus kaustophilus 19.0 19.0 1 PMID:16584181 -5.1.1.10 n-succinyl-l-phenylalanine geobacillus kaustophilus 5.0 5.0 1 * -5.1.1.10 n-succinyl-l-ser geobacillus kaustophilus 45.0 45.0 1 PMID:16584181 -5.1.1.10 n-succinyl-l-trp geobacillus kaustophilus 7.9 7.9 1 PMID:16584181 -5.1.1.10 n-succinyl-l-tyr geobacillus kaustophilus 52.0 52.0 1 PMID:16584181 -5.1.1.10 n-succinyl-l-val geobacillus kaustophilus 92.0 92.0 1 PMID:16584181 -5.1.1.11 l-phe brevibacillus brevis 0.38 0.38 1 PMID:20121951 -5.1.1.12 l-ornithine acetoanaerobium sticklandii 1660.0 1320.0 2 PMID:10715017;PMID:19251850 -5.1.1.13 d-aspartate acropora millepora 25.3 25.3 1 PMID:28744579 -5.1.1.13 d-aspartate anadara broughtonii 42.9 14.7 6 PMID:12670796;PMID:35997160 -5.1.1.13 d-aspartate anneissia japonica 2.53 2.53 1 PMID:35997160 -5.1.1.13 d-aspartate aplysia californica 77.7 77.7 1 PMID:35997160 -5.1.1.13 d-aspartate macrostomum lignano 0.323 0.323 1 PMID:35997160 -5.1.1.13 d-aspartate magallana gigas 13.1 13.1 1 PMID:28744579 -5.1.1.13 d-aspartate manihot esculenta 15.7 15.7 1 PMID:31622858 -5.1.1.13 d-aspartate penaeus monodon 27.6 27.6 1 PMID:28744579 -5.1.1.13 d-aspartate saccoglossus kowalevskii 45.1 7.47 3 PMID:30902582 -5.1.1.13 d-aspartate solanum lycopersicum 7.56 7.56 1 PMID:31622858 -5.1.1.13 d-aspartate sphagnum girgensohnii 2.96 2.96 1 PMID:31622858 -5.1.1.13 d-aspartate spirogyra pratensis 5.69 5.69 1 PMID:31622858 -5.1.1.13 d-aspartate thermococcus litoralis 610000.0 610000.0 1 PMID:27438592 -5.1.1.13 d-glutamate saccoglossus kowalevskii 11.3 11.3 1 PMID:30902582 -5.1.1.13 d-glutamic acid manihot esculenta 1.09 1.09 1 PMID:31622858 -5.1.1.13 d-serine manihot esculenta 0.517 0.517 1 PMID:31622858 -5.1.1.13 d-serine solanum lycopersicum 0.175 0.175 1 PMID:31622858 -5.1.1.13 d-serine sphagnum girgensohnii 0.141 0.141 1 PMID:31622858 -5.1.1.13 d-serine spirogyra pratensis 0.0773 0.0773 1 PMID:31622858 -5.1.1.13 l-aspartate acropora millepora 57.7 57.7 1 PMID:28744579 -5.1.1.13 l-aspartate anadara broughtonii 14.9 4.8 6 PMID:12670796;PMID:35997160 -5.1.1.13 l-aspartate anneissia japonica 0.934 0.934 1 PMID:35997160 -5.1.1.13 l-aspartate aplysia californica 19.5 19.5 1 PMID:35997160 -5.1.1.13 l-aspartate macrostomum lignano 0.463 0.463 1 PMID:35997160 -5.1.1.13 l-aspartate magallana gigas 8.65 8.65 1 PMID:28744579 -5.1.1.13 l-aspartate manihot esculenta 20.4 20.4 1 PMID:31622858 -5.1.1.13 l-aspartate microcystis aeruginosa 42.5 42.5 1 PMID:31101340 -5.1.1.13 l-aspartate penaeus monodon 33.0 33.0 1 PMID:28744579 -5.1.1.13 l-aspartate saccoglossus kowalevskii 41.6 3.63 3 PMID:30902582 -5.1.1.13 l-aspartate solanum lycopersicum 7.64 7.64 1 PMID:31622858 -5.1.1.13 l-aspartate sphagnum girgensohnii 7.52 7.52 1 PMID:31622858 -5.1.1.13 l-aspartate spirogyra pratensis 3.15 3.15 1 PMID:31622858 -5.1.1.13 l-aspartate streptococcus thermophilus 39.6 39.6 1 PMID:25596033 -5.1.1.13 l-aspartate thermococcus litoralis 118000.0 118000.0 1 PMID:27438592 -5.1.1.13 l-glutamate saccoglossus kowalevskii 6.7 6.7 1 PMID:30902582 -5.1.1.13 l-glutamic acid manihot esculenta 0.721 0.721 1 PMID:31622858 -5.1.1.13 l-serine manihot esculenta 0.272 0.272 1 PMID:31622858 -5.1.1.13 l-serine solanum lycopersicum 0.0631 0.0631 1 PMID:31622858 -5.1.1.13 l-serine sphagnum girgensohnii 0.0599 0.0599 1 PMID:31622858 -5.1.1.13 l-serine spirogyra pratensis 0.0641 0.0641 1 PMID:31622858 -5.1.1.14 isonocardicin a nocardia uniformis 0.59 0.59 1 PMID:15252031 -5.1.1.14 nocardicin a nocardia uniformis 0.35 0.35 1 PMID:15252031 -5.1.1.15 d-2-aminobutyric acid amide ensifer sp. 23-3 1.1 1.1 1 PMID:28929416 -5.1.1.15 d-alanine amide ensifer sp. 23-3 10.2 10.2 1 PMID:28929416 -5.1.1.15 l-2-aminobutyric acid amide ensifer sp. 23-3 0.7 0.7 1 PMID:28929416 -5.1.1.15 l-2-aminohexano-6-lactam citreicella sp. se45 465.0 465.0 1 PMID:27544766 -5.1.1.15 l-2-aminohexano-6-lactam ensifer sp. 23-3 371.0 371.0 1 PMID:28929416 -5.1.1.15 l-alanine amide ensifer sp. 23-3 3.3 3.3 1 PMID:28929416 -5.1.1.18 d-serine acropora millepora 0.0551 0.0551 1 PMID:28744579 -5.1.1.18 d-serine amphimedon queenslandica 0.0925 0.0925 1 PMID:35997160 -5.1.1.18 d-serine anadara broughtonii 0.0732 0.0732 1 PMID:35997160 -5.1.1.18 d-serine anneissia japonica 0.0425 0.0425 1 PMID:35997160 -5.1.1.18 d-serine aplysia californica 0.146 0.146 1 PMID:35997160 -5.1.1.18 d-serine bombyx mori 0.11 0.11 1 PMID:35325141 -5.1.1.18 d-serine dictyostelium discoideum 1.03 1.03 1 PMID:32474107 -5.1.1.18 d-serine homo sapiens 1.41 1.41 1 PMID:18812225 -5.1.1.18 d-serine macrostomum lignano 0.0799 0.0799 1 PMID:35997160 -5.1.1.18 d-serine magallana gigas 0.00211 0.00211 1 PMID:28744579 -5.1.1.18 d-serine manihot esculenta 0.0517 0.0517 1 PMID:31622858 -5.1.1.18 d-serine mus musculus 14.5 1.0825 6 PMID:15536068;PMID:16185077;PMID:18812225;PMID:28744579 -5.1.1.18 d-serine oryza sativa 0.31 0.255 2 PMID:20564571 -5.1.1.18 d-serine penaeus monodon 0.00772 0.00772 1 PMID:28744579 -5.1.1.18 d-serine pyrobaculum islandicum 5.22 5.22 1 PMID:17965169 -5.1.1.18 d-serine roseobacter litoralis 2.22 2.22 1 PMID:26475231 -5.1.1.18 d-serine solanum lycopersicum 0.0428 0.0428 1 PMID:31622858 -5.1.1.18 l-serine acropora millepora 0.0414 0.0414 1 PMID:28744579 -5.1.1.18 l-serine amphimedon queenslandica 0.0591 0.0591 1 PMID:35997160 -5.1.1.18 l-serine anadara broughtonii 0.0533 0.0533 1 PMID:35997160 -5.1.1.18 l-serine anneissia japonica 0.104 0.104 1 PMID:35997160 -5.1.1.18 l-serine aplysia californica 0.107 0.107 1 PMID:35997160 -5.1.1.18 l-serine bombyx mori 0.1 0.1 1 PMID:35325141 -5.1.1.18 l-serine caenorhabditis elegans 0.357 0.357 1 PMID:27458110 -5.1.1.18 l-serine dictyostelium discoideum 2.38 2.38 1 PMID:32474107 -5.1.1.18 l-serine homo sapiens 2.77 0.317 6 PMID:18812225;PMID:23992455;PMID:29410194;PMID:29899358;PMID:30687716 -5.1.1.18 l-serine macrostomum lignano 0.0951 0.0951 1 PMID:35997160 -5.1.1.18 l-serine magallana gigas 0.00178 0.00178 1 PMID:28744579 -5.1.1.18 l-serine manihot esculenta 0.06 0.06 1 PMID:31622858 -5.1.1.18 l-serine mus musculus 4.0 0.78 7 PMID:15536068;PMID:16185077;PMID:18812225;PMID:27387750;PMID:28744579 -5.1.1.18 l-serine oryza sativa 0.36 0.33499999999999996 2 PMID:20564571 -5.1.1.18 l-serine penaeus monodon 0.00871 0.00871 1 PMID:28744579 -5.1.1.18 l-serine pyrobaculum islandicum 14.8 14.8 1 PMID:17965169 -5.1.1.18 l-serine roseobacter litoralis 2.04 2.04 1 PMID:26475231 -5.1.1.18 l-serine solanum lycopersicum 0.0287 0.0287 1 PMID:31622858 -5.1.1.18 l-serine o-sulfate mus musculus 0.49 0.49 1 PMID:16185077 -5.1.1.19 o-ureido-d-serine streptomyces lavendulae subsp. lavendulae 29.0 29.0 1 PMID:22307920 -5.1.1.19 o-ureido-l-serine streptomyces lavendulae subsp. lavendulae 158.0 158.0 1 PMID:22307920 -5.1.1.2 d-leucine thermococcus kodakarensis 108.0 108.0 1 PMID:33468590 -5.1.1.2 d-methionine thermococcus kodakarensis 86.0 86.0 1 PMID:33468590 -5.1.1.2 d-methionine thermococcus litoralis 1.8 1.8 2 PMID:33942867 -5.1.1.2 l-leucine thermococcus kodakarensis 43.3 43.3 1 PMID:33468590 -5.1.1.2 l-methionine thermococcus kodakarensis 54.4 54.4 1 PMID:33468590 -5.1.1.2 l-methionine thermococcus litoralis 1.1 1.1 2 PMID:33942867 -5.1.1.20 l-ala-d-asp bacillus subtilis 0.053 0.053 1 PMID:11747447 -5.1.1.20 l-ala-d-asp escherichia coli 17.0 17.0 1 PMID:11747447 -5.1.1.20 l-ala-d-gln escherichia coli 3.3 3.3 1 PMID:11747447 -5.1.1.20 l-ala-d-glu bacillus subtilis 15.0 15.0 1 PMID:11747447 -5.1.1.20 l-ala-d-glu escherichia coli 10.0 10.0 1 PMID:11747447 -5.1.1.20 l-ala-d-met bacillus subtilis 1.1 1.1 1 PMID:11747447 -5.1.1.20 l-ala-d-met escherichia coli 1.9 1.9 1 PMID:11747447 -5.1.1.21 3-ethyl-d-norvaline lentilactobacillus buchneri 137.0 137.0 1 PMID:31528932 -5.1.1.21 3-ethyl-l-norvaline lentilactobacillus buchneri 215.0 215.0 1 PMID:31528932 -5.1.1.21 d-2-cyclohexylglycine lentilactobacillus buchneri 202.0 202.0 1 PMID:31528932 -5.1.1.21 d-allo-isoleucine lentilactobacillus buchneri 939.0 939.0 3 PMID:24039265;PMID:28471367;PMID:31528932 -5.1.1.21 l-2-cyclohexylglycine lentilactobacillus buchneri 148.0 148.0 1 PMID:31528932 -5.1.1.21 l-isoleucine arabidopsis thaliana 11.03 11.03 1 PMID:26324904 -5.1.1.21 l-isoleucine lentilactobacillus buchneri 502.0 502.0 3 PMID:24039265;PMID:28471367;PMID:31528932 -5.1.1.22 l-proline betaine salipiger bermudensis 5.3 5.3 1 PMID:24056934 -5.1.1.22 trans-4-hydroxy-l-proline betaine salipiger bermudensis 330.0 330.0 1 PMID:24056934 -5.1.1.24 d-histidine leuconostoc mesenteroides subsp. mesenteroides 185.4 185.4 1 PMID:30377839 -5.1.1.24 d-histidine leuconostoc mesenteroides subsp. sake 185.42 185.42 1 PMID:30377839 -5.1.1.24 l-histidine leuconostoc mesenteroides subsp. mesenteroides 96.9 96.9 1 PMID:30377839 -5.1.1.24 l-histidine leuconostoc mesenteroides subsp. sake 96.95 96.95 1 PMID:30377839 -5.1.1.3 d-aspartate saccoglossus kowalevskii 45.1 26.285 2 PMID:30902582 -5.1.1.3 d-glu limosilactobacillus fermentum 69.0 69.0 1 PMID:8385993 -5.1.1.3 d-glutamate aquifex pyrophilus 3.3 1.678 2 PMID:10331867;PMID:18576402 -5.1.1.3 d-glutamate bacillus anthracis 780.0 2.0 5 PMID:17496086;PMID:17610893;PMID:19552402 -5.1.1.3 d-glutamate bacillus subtilis 8.3 4.72 3 PMID:19309142;PMID:19772853;PMID:30194685 -5.1.1.3 d-glutamate burkholderia cenocepacia 0.025 0.025 1 PMID:27898711 -5.1.1.3 d-glutamate enterococcus faecalis 11.73 6.07 2 PMID:17568739 -5.1.1.3 d-glutamate enterococcus faecium 15.0 15.0 1 PMID:17568739 -5.1.1.3 d-glutamate escherichia coli 43.33 43.33 1 PMID:17568739 -5.1.1.3 d-glutamate fusobacterium nucleatum 26.0 26.0 1 PMID:30194685 -5.1.1.3 d-glutamate fusobacterium nucleatum subsp. nucleatum 26.0 24.0 2 PMID:19772853 -5.1.1.3 d-glutamate helicobacter pylori 0.2 0.2 1 PMID:17568739 -5.1.1.3 d-glutamate lactiplantibacillus plantarum 5980.0 5980.0 1 PMID:23228473 -5.1.1.3 d-glutamate limosilactobacillus fermentum 68.0 68.0 1 PMID:11371180 -5.1.1.3 d-glutamate mycobacterium tuberculosis 12.6 12.6 1 PMID:27480853 -5.1.1.3 d-glutamate saccoglossus kowalevskii 11.3 11.3 3 PMID:30902582 -5.1.1.3 d-glutamate staphylococcus aureus 0.56 0.56 1 PMID:17568739 -5.1.1.3 d-glutamate streptococcus mutans 0.0306 0.0306 1 PMID:31875162 -5.1.1.3 d-glutamate streptococcus pyogenes 0.49 0.49 1 PMID:17658548 -5.1.1.3 d-glutamate thermus thermophilus 0.96 0.96 1 PMID:32474108 -5.1.1.3 d-homocysteic acid bacillus subtilis 26.0 26.0 1 PMID:30194685 -5.1.1.3 d-homocysteic acid fusobacterium nucleatum 17.0 17.0 1 PMID:30194685 -5.1.1.3 l-2-aminoadipic acid fusobacterium nucleatum subsp. nucleatum 2.4 2.4 1 PMID:19772853 -5.1.1.3 l-aspartate saccoglossus kowalevskii 41.6 22.615000000000002 2 PMID:30902582 -5.1.1.3 l-glu limosilactobacillus fermentum 76.0 76.0 1 PMID:8385993 -5.1.1.3 l-glutamate aquifex pyrophilus 0.21 0.21 1 PMID:10331867 -5.1.1.3 l-glutamate bacillus anthracis 116600.0 18.0 5 PMID:17496086;PMID:17610893;PMID:19552402 -5.1.1.3 l-glutamate bacillus subtilis 87.0 42.0 5 PMID:15502318;PMID:19309142;PMID:19772853;PMID:26539562;PMID:30194685 -5.1.1.3 l-glutamate enterococcus faecalis 25.0 25.0 1 PMID:17568739 -5.1.1.3 l-glutamate enterococcus faecium 36.66 20.029999999999998 2 PMID:17568739 -5.1.1.3 l-glutamate escherichia coli 12.16 6.285 2 PMID:17568739 -5.1.1.3 l-glutamate fusobacterium nucleatum 17.5 17.5 1 PMID:30194685 -5.1.1.3 l-glutamate fusobacterium nucleatum subsp. nucleatum 17.4 15.6 2 PMID:19772853 -5.1.1.3 l-glutamate helicobacter pylori 1.05 1.05 1 PMID:17568739 -5.1.1.3 l-glutamate lactiplantibacillus plantarum 3029.0 3029.0 1 PMID:23228473 -5.1.1.3 l-glutamate limosilactobacillus fermentum 69.0 69.0 1 PMID:11371180 -5.1.1.3 l-glutamate mycobacterium tuberculosis 226.4 226.4 1 PMID:27480853 -5.1.1.3 l-glutamate saccoglossus kowalevskii 6.7 6.7 3 PMID:30902582 -5.1.1.3 l-glutamate staphylococcus aureus 8.5 8.5 1 PMID:17568739 -5.1.1.3 l-glutamate streptococcus mutans 0.0378 0.0378 1 PMID:31875162 -5.1.1.3 l-glutamate streptococcus pyogenes 1.63 1.63 1 PMID:17658548 -5.1.1.3 l-glutamate thermotoga maritima 1.0 0.512 2 PMID:28640457 -5.1.1.3 l-glutamate thermus thermophilus 17.71 17.71 1 PMID:32474108 -5.1.1.3 l-glutamate wolbachia pipientis 0.017 0.017 1 PMID:28640457 -5.1.1.4 d-proline clostridioides difficile 2.48 2.48 1 PMID:25786142 -5.1.1.4 d-proline ferroplasma acidarmanus 0.119 0.119 1 PMID:25786142 -5.1.1.4 d-proline thermococcus litoralis 2.22 2.22 1 PMID:25786142 -5.1.1.4 l-proline clostridioides difficile 14.15 14.15 1 PMID:25786142 -5.1.1.4 l-proline ferroplasma acidarmanus 0.6 0.6 1 PMID:25786142 -5.1.1.4 l-proline thermococcus litoralis 2.78 2.78 1 PMID:25786142 -5.1.1.5 d-lysine oenococcus oeni 2.83 2.83 1 PMID:23035128 -5.1.1.5 d-lysine uncultured bacterium 2.16 2.16 1 PMID:19502445 -5.1.1.5 d-ornithine oenococcus oeni 1.83 1.83 1 PMID:23035128 -5.1.1.5 l-arginine proteus mirabilis 10.83 10.83 2 PMID:23118975 -5.1.1.5 l-lysine oenococcus oeni 3.5 3.5 1 PMID:23035128 -5.1.1.5 l-lysine proteus mirabilis 55.43 55.43 2 PMID:23118975 -5.1.1.5 l-lysine uncultured bacterium 5.1 5.1 1 PMID:19502445 -5.1.1.5 l-ornithine oenococcus oeni 1.83 1.83 1 PMID:23035128 -5.1.1.6 d-allo-threonine dictyostelium discoideum 3.81 3.81 1 PMID:32474107 -5.1.1.6 d-allo-threonine mus musculus 4.29 4.29 1 PMID:32474107 -5.1.1.6 d-threonine dictyostelium discoideum 0.038 0.038 1 PMID:32474107 -5.1.1.6 l-allo-threonine dictyostelium discoideum 0.015 0.015 1 PMID:32474107 -5.1.1.6 l-allo-threonine mus musculus 19.6 19.6 1 PMID:32474107 -5.1.1.6 l-threonine dictyostelium discoideum 1.78 1.78 1 PMID:32474107 -5.1.1.7 ll-2,6-diaminoheptanedioate haemophilus influenzae 128.0 128.0 1 * -5.1.1.7 ll-diaminoheptanedioate escherichia coli 84.0 84.0 1 PMID:6378903;PMID:9559056 -5.1.1.7 meso-diaminoheptanedioate escherichia coli 67.0 67.0 1 PMID:6378903;PMID:9559056 -5.1.1.7 meso-diaminoheptanedioate mycobacterium tuberculosis 0.1465 0.1465 1 PMID:18269631 -5.1.1.8 cis-4-hydroxy-d-proline thermococcus litoralis 3.83 3.83 1 PMID:25786142 -5.1.1.8 trans-3-hydroxy-l-proline thermococcus litoralis 3.6 3.6 1 PMID:25786142 -5.1.1.8 trans-4-hydroxy-l-proline ferroplasma acidarmanus 0.0395 0.0395 1 PMID:25786142 -5.1.1.8 trans-4-hydroxy-l-proline thermococcus litoralis 12.13 12.13 1 PMID:25786142 -5.1.1.9 d-alanine pseudomonas taetrolens 2.6 2.6 1 PMID:20564572 -5.1.1.9 d-arginine pseudomonas taetrolens 119.0 119.0 1 PMID:20564572 -5.1.1.9 d-lysine pseudomonas taetrolens 104.0 104.0 1 PMID:20564572 -5.1.1.9 d-ornithine pseudomonas taetrolens 83.3 83.3 1 PMID:20564572 -5.1.1.9 l-alanine pseudomonas taetrolens 2.4 2.4 1 PMID:20564572 -5.1.1.9 l-arginine pseudomonas taetrolens 119.0 119.0 1 PMID:20564572 -5.1.1.9 l-lysine pseudomonas taetrolens 109.0 109.0 1 PMID:20564572 -5.1.1.9 l-ornithine pseudomonas taetrolens 87.7 87.7 1 PMID:20564572 -5.1.2.1 (r)-lactate lactiplantibacillus plantarum 1333.0 1333.0 1 PMID:24710389 -5.1.2.1 (s)-lactate lactiplantibacillus plantarum 4745.0 4745.0 1 PMID:24710389 -5.1.2.1 d-lactate latilactobacillus sakei 16.7 16.7 1 PMID:5707819 -5.1.2.1 l-lactate latilactobacillus sakei 6.67 6.67 1 PMID:5707819 -5.1.2.2 (2r)-2-naphthylglycolate pseudomonas putida 70.0 58.0 2 PMID:24411454 -5.1.2.2 (r)-2-chloromandelate pseudomonas putida 0.9 0.9 1 PMID:27557723 -5.1.2.2 (r)-2-hydroxy-3-butenoic acid pseudomonas putida 240.0 240.0 1 * -5.1.2.2 (r)-2-naphthylglycolate pseudomonas putida 70.0 46.0 3 PMID:14992589;PMID:18092808 -5.1.2.2 (r)-2-naphtylglycolate pseudomonas putida 70.0 58.0 2 PMID:18092808 -5.1.2.2 (r)-3-chloromandelate pseudomonas putida 469.0 469.0 1 PMID:24411454 -5.1.2.2 (r)-mandelamide pseudomonas putida 11.03 11.03 1 PMID:24411454 -5.1.2.2 (r)-mandelate pseudomonas putida 1029.0 620.0 13 PMID:11063568;PMID:15966725;PMID:18092808;PMID:21894901;PMID:29850884;PMID:30935886;PMID:34339165;PMID:35016855;PMID:7893689;PMID:7893690 -5.1.2.2 (r)-trifluorolactate pseudomonas putida 2.0 2.0 1 PMID:21894901 -5.1.2.2 (s)-2-chloromandelate pseudomonas putida 0.99 0.99 1 PMID:27557723 -5.1.2.2 (s)-2-hydroxy-3-butenoic acid pseudomonas putida 250.0 250.0 1 * -5.1.2.2 (s)-2-naphthylglycolate pseudomonas putida 38.4 32.0 5 PMID:14992589;PMID:18092808 -5.1.2.2 (s)-mandelate pseudomonas putida 1124.0 492.0 17 PMID:11063568;PMID:15966725;PMID:18092808;PMID:19589387;PMID:21894901;PMID:29850884;PMID:30935886;PMID:34339165;PMID:35016855;PMID:7893689 -5.1.2.2 (s)-trifluorolactate pseudomonas putida 2.5 2.5 1 PMID:21894901 -5.1.2.2 d-mandelate pseudomonas putida 1070.0 1070.0 1 PMID:386722 -5.1.2.7 d-fructuronate thermotoga maritima 6.5 6.5 1 PMID:22925190 -5.1.3.1 d-ribulose 5-phosphate saccharomyces cerevisiae 1300.0 1300.0 1 PMID:4560420 -5.1.3.1 d-ribulose 5-phosphate spinacia oleracea 7100.0 3550.069 2 PMID:9523694;PMID:9890975 -5.1.3.1 d-ribulose 5-phosphate streptococcus pyogenes 870.0 660.0 4 PMID:16489742 -5.1.3.1 d-xylulose 5-phosphate saccharomyces cerevisiae 1300.0 1300.0 1 PMID:4560420 -5.1.3.11 4-o-beta-d-mannopyranosyl-beta-d-mannopyranose bacteroides fragilis 104.0 104.0 1 PMID:27031293 -5.1.3.11 4-o-beta-d-mannopyranosyl-beta-d-mannopyranose cellvibrio vulgaris 102.0 102.0 2 PMID:25704402;PMID:27031293 -5.1.3.11 4-o-beta-d-mannopyranosyl-beta-d-mannopyranose rhodothermus marinus 102.0 102.0 1 PMID:27031293 -5.1.3.11 4-o-beta-d-mannopyranosyl-beta-d-mannopyranose ruminococcus albus 201.0 201.0 1 PMID:27031293 -5.1.3.11 4-o-beta-d-mannopyranosyl-beta-d-mannopyranose winmispira thermophila 35.8 35.8 2 PMID:27031293 -5.1.3.11 cellobiose [eubacterium] cellulosolvens 32.5 28.5 3 PMID:18710396;PMID:27031293 -5.1.3.11 cellobiose bacteroides fragilis 67.6 67.6 3 PMID:19202279;PMID:27031293 -5.1.3.11 cellobiose caldicellulosiruptor obsidiansis 255.2 244.45 2 PMID:27873314 -5.1.3.11 cellobiose caldicellulosiruptor saccharolyticus 126.1 126.1 1 PMID:31733243 -5.1.3.11 cellobiose cellvibrio vulgaris 38.8 38.8 2 PMID:25704402;PMID:27031293 -5.1.3.11 cellobiose dictyoglomus thermophilum 320.0 320.0 1 PMID:31401280 -5.1.3.11 cellobiose dictyoglomus turgidum 169.1 169.1 3 PMID:22782272;PMID:27031293 -5.1.3.11 cellobiose dyadobacter fermentans 240.0 240.0 1 PMID:27031293 -5.1.3.11 cellobiose flavobacterium johnsoniae 39.9 39.9 2 PMID:27031293 -5.1.3.11 cellobiose geotrichum fermentans 240.0 240.0 1 * -5.1.3.11 cellobiose herpetosiphon aurantiacus 18.7 18.7 2 PMID:27031293 -5.1.3.11 cellobiose pedobacter heparinus 7.02 7.02 2 PMID:27031293 -5.1.3.11 cellobiose rhodothermus marinus 80.8 80.8 3 PMID:22056431;PMID:27031293 -5.1.3.11 cellobiose roseburia intestinalis 98.5 98.5 1 PMID:32684457 -5.1.3.11 cellobiose ruminococcus albus 63.8 63.8 5 PMID:18392616;PMID:19202279;PMID:19330485;PMID:27031293 -5.1.3.11 cellobiose saccharophagus degradans 26.1 26.1 2 PMID:27031293 -5.1.3.11 cellobiose spirosoma linguale 222.0 222.0 2 PMID:27031293 -5.1.3.11 cellobiose teredinibacter turnerae 165.0 165.0 2 PMID:27031293 -5.1.3.11 cellobiose thermoanaerobacterium saccharolyticum 100.4 100.4 2 * -5.1.3.11 cellobiose thermoanaerobacterium thermosaccharolyticum 247.0 247.0 1 PMID:31401280 -5.1.3.11 cellobiose thermothelomyces thermophilus 8.0 8.0 1 * -5.1.3.11 cellobiose treponema brennaborense 77.7 77.7 1 PMID:34231359 -5.1.3.11 cellobiose uncultured bacterium 166.0 137.5 2 PMID:25487892 -5.1.3.11 cellobiose winmispira thermophila 8.0 8.0 3 PMID:23801120;PMID:27031293 -5.1.3.11 d-galactose rhodothermus marinus 5.0 5.0 1 PMID:30275414 -5.1.3.11 d-glucose caldicellulosiruptor saccharolyticus 0.27 0.27 1 PMID:21691788 -5.1.3.11 d-mannose caldicellulosiruptor saccharolyticus 0.74 0.74 1 PMID:21691788 -5.1.3.11 d-mannose cellvibrio vulgaris 0.113 0.113 1 PMID:25704402 -5.1.3.11 d-mannose rhodothermus marinus 5.4 4.6 2 PMID:30275414 -5.1.3.11 epilactose caldicellulosiruptor saccharolyticus 101.0 101.0 2 * -5.1.3.11 epilactose dictyoglomus turgidum 125.0 125.0 2 * -5.1.3.11 lactose [eubacterium] cellulosolvens 32.5 32.5 3 PMID:18710396;PMID:27031293 -5.1.3.11 lactose bacteroides fragilis 79.5 79.5 3 PMID:19202279;PMID:27031293 -5.1.3.11 lactose caldicellulosiruptor morganii 187.6 187.6 1 PMID:34031874 -5.1.3.11 lactose caldicellulosiruptor obsidiansis 233.4 225.85000000000002 2 PMID:27873314 -5.1.3.11 lactose caldicellulosiruptor saccharolyticus 303.0 171.125 20 PMID:27080880;PMID:31733243;PMID:33135681;PMID:33541071;PMID:36475670 -5.1.3.11 lactose cellvibrio vulgaris 18.6 18.6 2 PMID:25704402;PMID:27031293 -5.1.3.11 lactose dictyoglomus thermophilum 441.4 441.4 1 PMID:31401280 -5.1.3.11 lactose dictyoglomus turgidum 237.0 89.4 5 PMID:22782272;PMID:27031293 -5.1.3.11 lactose dyadobacter fermentans 44.9 44.9 1 PMID:27031293 -5.1.3.11 lactose flavobacterium johnsoniae 17.5 17.5 2 PMID:27031293 -5.1.3.11 lactose geotrichum fermentans 44.9 44.9 1 * -5.1.3.11 lactose herpetosiphon aurantiacus 14.0 14.0 2 PMID:27031293 -5.1.3.11 lactose pedobacter heparinus 5.43 5.43 2 PMID:27031293 -5.1.3.11 lactose rhodothermus marinus 111.0 111.0 3 PMID:22056431;PMID:27031293 -5.1.3.11 lactose roseburia intestinalis 117.0 117.0 1 PMID:32684457 -5.1.3.11 lactose ruminococcus albus 52.1 52.1 5 PMID:18392616;PMID:19202279;PMID:19330485;PMID:27031293 -5.1.3.11 lactose saccharophagus degradans 7.82 7.82 2 PMID:27031293 -5.1.3.11 lactose spirosoma linguale 92.1 92.1 2 PMID:27031293 -5.1.3.11 lactose teredinibacter turnerae 175.0 175.0 2 PMID:27031293 -5.1.3.11 lactose thermoanaerobacterium saccharolyticum 30.9 30.9 2 * -5.1.3.11 lactose thermoanaerobacterium thermosaccharolyticum 200.0 200.0 1 PMID:31401280 -5.1.3.11 lactose treponema brennaborense 135.1 135.1 1 PMID:34231359 -5.1.3.11 lactulose caldicellulosiruptor saccharolyticus 0.88 0.88 2 * -5.1.3.11 lactulose dictyoglomus turgidum 0.54 0.54 2 * -5.1.3.11 mannobiose uncultured bacterium 137.0 125.0 2 PMID:25487892 -5.1.3.11 mannobiose winmispira thermophila 35.7 35.7 1 PMID:23801120 -5.1.3.13 dtdp-6-deoxy-d-xylo-4-hexulose salmonella enterica 39.0 19.5475 4 PMID:10455186;PMID:17046787 -5.1.3.14 udp-n-acetyl-alpha-d-glucosamine neisseria meningitidis serogroup a / serotype 4a 31.0 31.0 1 PMID:26598987 -5.1.3.14 udp-n-acetyl-alpha-d-mannosamine neisseria meningitidis serogroup a / serotype 4a 52.0 52.0 1 PMID:26598987 -5.1.3.14 udp-n-acetyl-d-glucosamine bacillus anthracis 7.9 7.9 1 * -5.1.3.14 udp-n-acetyl-d-glucosamine escherichia coli 7.1 3.625 2 PMID:15210128 -5.1.3.14 udp-n-acetyl-d-glucosamine methanococcus maripaludis 3.4 3.4 1 PMID:18263721 -5.1.3.14 udp-n-acetyl-d-glucosamine rattus norvegicus 0.33 0.33 1 PMID:12603133 -5.1.3.15 alpha-d-glucose 6-phosphate saccharomyces cerevisiae 1950.0 1950.0 1 PMID:1092547;PMID:236478 -5.1.3.15 beta-d-glucose 6-phosphate saccharomyces cerevisiae 446.0 446.0 1 PMID:1092547;PMID:236478 -5.1.3.17 uronic acid residues bos taurus 620.0 620.0 1 PMID:7929434 -5.1.3.18 gdp-alpha-d-mannose arabidopsis thaliana 0.041 0.041 1 PMID:35087867 -5.1.3.18 gdp-alpha-d-mannose candidatus methylacidiphilum fumarolicum 0.2 0.2 1 PMID:35087867 -5.1.3.18 gdp-alpha-d-mannose oryza sativa 0.03 0.03 1 PMID:35087867 -5.1.3.18 gdp-d-mannose arabidopsis thaliana 0.041 0.01 3 PMID:12954627 -5.1.3.18 gdp-d-mannose oryza sativa 0.127 0.0785 2 PMID:16413588 -5.1.3.2 d-galactose escherichia coli 0.00026 0.00026 1 PMID:20717852 -5.1.3.2 d-tagatose escherichia coli 0.00545 0.00545 1 PMID:20717852 -5.1.3.2 udp-alpha-d-galactose campylobacter jejuni subsp. jejuni 290.1 290.1 1 PMID:15509570 -5.1.3.2 udp-alpha-d-galactose davallia divaricata 0.37 0.235 2 PMID:31888381 -5.1.3.2 udp-alpha-d-galactose magallana gigas 2.23 2.23 1 PMID:29844279 -5.1.3.2 udp-alpha-d-galactose pseudomonas aeruginosa 0.00313 0.00313 1 PMID:10747995 -5.1.3.2 udp-alpha-d-galactose pyrococcus horikoshii 1.0 1.0 1 PMID:22342090 -5.1.3.2 udp-alpha-d-galactose thermotoga maritima 14677.0 11217.0 2 PMID:26344854 -5.1.3.2 udp-alpha-d-glucose aspergillus nidulans 12.8 12.8 1 PMID:24116166 -5.1.3.2 udp-alpha-d-glucose campylobacter jejuni subsp. jejuni 73.95 73.95 1 PMID:15509570 -5.1.3.2 udp-alpha-d-glucose davallia divaricata 0.37 0.27 2 PMID:31888381 -5.1.3.2 udp-alpha-d-glucose escherichia coli 760.0 250.0 3 PMID:23339688;PMID:29159585 -5.1.3.2 udp-alpha-d-glucose pseudomonas aeruginosa 0.00207 0.00207 1 PMID:10747995 -5.1.3.2 udp-alpha-d-glucose pyrococcus horikoshii 1.1 1.1 1 PMID:22342090 -5.1.3.2 udp-alpha-d-glucose thermotoga maritima 14677.0 11217.0 2 PMID:26344854 -5.1.3.2 udp-d-galactose arabidopsis thaliana 64.0 27.0 5 PMID:19754426 -5.1.3.2 udp-d-xylose lathyrus oleraceus 17.0 17.0 1 PMID:19754426 -5.1.3.2 udp-galactose aeromonas hydrophila 116.0 64.45 2 PMID:17553760;PMID:20587332 -5.1.3.2 udp-galactose arabidopsis thaliana 128.0 66.0 5 PMID:16644739 -5.1.3.2 udp-galactose campylobacter jejuni 290.1 290.1 1 PMID:15509570 -5.1.3.2 udp-galactose escherichia coli 750.0 625.0 2 PMID:20717852 -5.1.3.2 udp-galactose homo sapiens 36.0 36.0 1 PMID:16302980 -5.1.3.2 udp-galactose hordeum vulgare 21.0 21.0 1 PMID:16266295 -5.1.3.2 udp-galactose lathyrus oleraceus 64.0 64.0 1 PMID:19754426 -5.1.3.2 udp-galactose pyrobaculum calidifontis 0.84 0.84 1 PMID:21645492 -5.1.3.2 udp-galactose thermus thermophilus 199.1 127.21 2 PMID:19800315 -5.1.3.2 udp-galnac campylobacter jejuni 247.9 247.9 1 PMID:15509570 -5.1.3.2 udp-galnac hordeum vulgare 0.12 0.12 1 PMID:16266295 -5.1.3.2 udp-glcnac campylobacter jejuni 82.3 82.3 1 PMID:15509570 -5.1.3.2 udp-glcnac hordeum vulgare 0.07 0.07 1 PMID:16266295 -5.1.3.2 udp-glucose arabidopsis thaliana 33.0 24.0 5 PMID:16644739 -5.1.3.2 udp-glucose campylobacter jejuni 73.95 73.95 1 PMID:15509570 -5.1.3.2 udp-glucose escherichia coli 18.0 18.0 1 * -5.1.3.2 udp-glucose hordeum vulgare 11.0 11.0 1 PMID:16266295 -5.1.3.2 udp-glucose lathyrus oleraceus 9.0 9.0 1 PMID:19754426 -5.1.3.2 udp-l-arabinose lathyrus oleraceus 23.0 23.0 1 PMID:19754426 -5.1.3.2 udp-n-acetyl-alpha-d-galactosamine thermotoga maritima 38295.0 38295.0 1 PMID:26344854 -5.1.3.2 udp-n-acetyl-alpha-d-glucosamine marinithermus hydrothermalis 2.62 2.62 1 PMID:23250228 -5.1.3.2 udp-n-acetyl-alpha-d-glucosamine thermotoga maritima 27671.0 27671.0 1 PMID:26344854 -5.1.3.2 udp-xylose lathyrus oleraceus 17.0 17.0 1 PMID:19754426 -5.1.3.2 udpgalactose escherichia coli 960.0 760.0 3 PMID:14235524;PMID:7873670;PMID:9271498 -5.1.3.2 udpgalactose saccharomyces cerevisiae 64.8 64.8 1 PMID:6292668;PMID:6987227 -5.1.3.25 dtdp-6-deoxy-beta-l-talose burkholderia thailandensis 0.9 0.9 1 PMID:21640586 -5.1.3.3 alpha-d-fucose lactococcus lactis 1700.0 1700.0 1 PMID:12218067 -5.1.3.3 alpha-d-galactose escherichia coli 18400.0 18400.0 1 PMID:12693937 -5.1.3.3 alpha-d-galactose homo sapiens 12000.0 12000.0 1 PMID:12753898 -5.1.3.3 alpha-d-galactose lactococcus lactis 3700.0 3700.0 2 PMID:12218067;PMID:12717027 -5.1.3.3 alpha-d-glucose aspergillus niger 2600.0 2600.0 1 PMID:7317442 -5.1.3.3 alpha-d-glucose bos taurus 16500.0 16500.0 1 PMID:4709943 -5.1.3.3 alpha-d-glucose capsicum frutescens 13300.0 13300.0 1 PMID:805343 -5.1.3.3 alpha-d-glucose escherichia coli 22000.0 20500.0 2 PMID:12693937;PMID:9778377 -5.1.3.3 alpha-d-glucose homo sapiens 4900.0 4900.0 1 PMID:12753898 -5.1.3.3 alpha-d-glucose lactococcus lactis 430.0 430.0 2 PMID:12218067;PMID:12717027 -5.1.3.3 alpha-d-quinovose lactococcus lactis 490.0 490.0 1 PMID:12218067 -5.1.3.3 alpha-d-xylose lactococcus lactis 410.0 410.0 2 PMID:12218067;PMID:12717027 -5.1.3.3 alpha-l-arabinose lactococcus lactis 5500.0 5500.0 2 PMID:12218067;PMID:12717027 -5.1.3.30 d-fructose [clostridium] scindens 350.0 350.0 1 PMID:23646168 -5.1.3.30 d-fructose clostridium sp. 273.0 273.0 1 PMID:23660703 -5.1.3.30 d-fructose desmospora sp. 8437 63570.0 63570.0 1 PMID:24199681 -5.1.3.30 d-fructose enterocloster bolteae 59.0 59.0 1 PMID:23644747 -5.1.3.30 d-fructose ruminiclostridium cellulolyticum 55.9 55.9 1 PMID:21663329 -5.1.3.30 d-fructose ruminococcus sp. 59.4 41.08 3 PMID:22760176;PMID:31797048 -5.1.3.30 d-fructose treponema primitia 292.88 292.88 1 PMID:25809188 -5.1.3.30 d-psicose [clostridium] scindens 1827.0 1827.0 1 PMID:23646168 -5.1.3.30 d-psicose clostridium sp. 536.0 536.0 1 PMID:23660703 -5.1.3.30 d-psicose desmospora sp. 8437 85.95 85.95 1 PMID:24199681 -5.1.3.30 d-psicose enterocloster bolteae 49.0 49.0 1 PMID:23644747 -5.1.3.30 d-psicose ruminiclostridium cellulolyticum 54.1 54.1 1 PMID:21663329 -5.1.3.30 d-psicose ruminococcus sp. 52.1 51.28 3 PMID:22760176;PMID:31797048 -5.1.3.30 d-psicose treponema primitia 502.77 502.77 1 PMID:25809188 -5.1.3.30 d-tagatose enterocloster bolteae 4.7 4.7 1 PMID:23644747 -5.1.3.31 d-fructose caballeronia insecticola 120.95 120.95 1 PMID:35871484 -5.1.3.31 d-fructose cereibacter sphaeroides 42.6 42.6 1 PMID:29121933 -5.1.3.31 d-fructose christensenella minuta 70.5 70.5 1 PMID:33363120 -5.1.3.31 d-fructose sinorhizobium sp. 50.0 50.0 1 PMID:35518988 -5.1.3.31 d-psicose caballeronia fortuita 540.0 540.0 1 PMID:31330210 -5.1.3.31 d-psicose caballeronia insecticola 204.05 204.05 1 PMID:35871484 -5.1.3.31 d-psicose cereibacter sphaeroides 20.47 20.47 1 PMID:29121933 -5.1.3.31 d-psicose christensenella minuta 109.5 109.5 1 PMID:33363120 -5.1.3.31 d-psicose mesorhizobium loti 0.0057 0.0057 1 PMID:23470755 -5.1.3.31 d-psicose sinorhizobium sp. 78.4 78.4 1 PMID:35518988 -5.1.3.31 d-sorbose caballeronia fortuita 137.6 137.6 1 PMID:31330210 -5.1.3.31 d-sorbose caballeronia insecticola 9.6 9.6 1 PMID:35871484 -5.1.3.31 d-sorbose cereibacter sphaeroides 8.3 8.3 1 PMID:29121933 -5.1.3.31 d-sorbose christensenella minuta 97.9 97.9 1 PMID:33363120 -5.1.3.31 d-sorbose sinorhizobium sp. 34.0 34.0 1 PMID:35518988 -5.1.3.31 d-tagatose caballeronia fortuita 711.1 711.1 1 PMID:31330210 -5.1.3.31 d-tagatose caballeronia insecticola 441.8 441.8 1 PMID:35871484 -5.1.3.31 d-tagatose cereibacter sphaeroides 48.31 48.31 1 PMID:29121933 -5.1.3.31 d-tagatose christensenella minuta 155.3 155.3 1 PMID:33363120 -5.1.3.31 d-tagatose mesorhizobium loti 0.057 0.057 1 PMID:23470755 -5.1.3.31 d-tagatose sinorhizobium sp. 98.3 98.3 1 PMID:35518988 -5.1.3.31 l-ribulose mesorhizobium loti 0.22 0.22 1 PMID:23470755 -5.1.3.31 l-xylulose mesorhizobium loti 0.14 0.14 1 PMID:23470755 -5.1.3.37 [alginate]-beta-d-mannuronate azotobacter vinelandii 14.0 14.0 1 PMID:10212201 -5.1.3.4 l-ribulose 5-phosphate escherichia coli 36.5 19.4 9 PMID:10769139;PMID:11732896;PMID:9548961 -5.1.3.40 d-tagatose 6-phosphate agrobacterium fabrum 8.7 8.7 1 PMID:26472925 -5.1.3.43 6-sulfo-alpha-d-quinovose herbaspirillum seropedicae 308.0 308.0 1 PMID:29535276 -5.1.3.43 6-sulfo-beta-d-quinovose herbaspirillum seropedicae 337.0 337.0 1 PMID:29535276 -5.1.3.44 beta-d-mannopyranose dyadobacter fermentans 3.9 3.9 1 PMID:31201453 -5.1.3.44 beta-d-mannopyranose runella slithyformis 4.76 4.76 1 PMID:31201453 -5.1.3.45 udp-n-acetyl-alpha-d-galactosaminuronate salmonella enterica subsp. enterica serovar typhi 0.652 0.652 1 PMID:16800641 -5.1.3.5 udp-alpha-d-xylopyranose hordeum vulgare 1.5 1.5 1 PMID:20435741 -5.1.3.5 udp-alpha-d-xylopyranose sinorhizobium meliloti 13.0 13.0 1 PMID:20847005 -5.1.3.5 udp-beta-l-arabinopyranose hordeum vulgare 1.5 1.5 1 PMID:20435741 -5.1.3.5 udp-d-xylopyranose sinorhizobium meliloti 13.0 13.0 1 PMID:20847005 -5.1.3.5 udp-d-xylose arabidopsis thaliana 19.0 0.5 5 PMID:19754426 -5.1.3.6 udp-d-galacturonate bacillus cereus 0.32 0.32 1 PMID:32645249 -5.1.3.6 udp-glucuronate arabidopsis thaliana 24.0 10.0 3 PMID:15563616;PMID:19564155 -5.1.3.6 udp-glucuronate bacillus cereus 0.25 0.25 1 PMID:32645249 -5.1.3.6 udp-glucuronate oryza sativa 37.4 37.4 1 PMID:19564155 -5.1.3.6 udp-glucuronate zea mays 10.1 10.1 1 PMID:19564155 -5.1.3.7 udp-alpha-d-galactose thermotoga maritima 7757.0 7757.0 1 PMID:26344854 -5.1.3.7 udp-alpha-d-glucose thermotoga maritima 14677.0 14677.0 1 PMID:26344854 -5.1.3.7 udp-d-galactose campylobacter jejuni 290.1 290.1 1 PMID:15509570 -5.1.3.7 udp-d-galactose pseudomonas aeruginosa 36.9 20.15 2 PMID:10747995 -5.1.3.7 udp-d-glucose campylobacter jejuni 73.95 73.95 1 PMID:15509570 -5.1.3.7 udp-d-glucose pseudomonas aeruginosa 0.52 0.52 1 PMID:10747995 -5.1.3.7 udp-glucose escherichia coli 3.335 3.335 1 PMID:29159585 -5.1.3.7 udp-n-acetyl-alpha-d-galactosamine thermotoga maritima 38295.0 32983.0 2 PMID:26344854 -5.1.3.7 udp-n-acetyl-alpha-d-glucosamine escherichia coli 43.5 43.5 2 PMID:29159585 -5.1.3.7 udp-n-acetyl-alpha-d-glucosamine marinithermus hydrothermalis 0.58 0.58 1 PMID:23250228 -5.1.3.7 udp-n-acetyl-alpha-d-glucosamine thermotoga maritima 38295.0 32983.0 2 PMID:26344854 -5.1.3.7 udp-n-acetyl-d-galactosamine campylobacter jejuni 247.9 247.9 1 PMID:15509570 -5.1.3.7 udp-n-acetyl-d-glucosamine campylobacter jejuni 82.3 82.3 1 PMID:15509570 -5.1.3.7 udp-n-acetyl-d-glucosamine pseudomonas aeruginosa 62300.0 44990.0 4 PMID:10747995 -5.1.3.8 n-acetyl-d-glucosamine trichormus variabilis 44.4 44.4 1 PMID:27178797 -5.1.99.1 dl-methylmalonyl-coa rattus norvegicus 4170.0 4170.0 1 PMID:2862845;PMID:3071715 -5.1.99.1 methylmalonyl-coa pyrococcus horikoshii 240.0 240.0 1 PMID:14586582 -5.1.99.3 (r)-allantoin klebsiella pneumoniae subsp. pneumoniae 238.0 238.0 1 PMID:21616082 -5.1.99.3 (r)-allantoin pseudomonas fluorescens 57.0 57.0 1 PMID:27797489 -5.1.99.3 (s)-allantoin klebsiella pneumoniae subsp. pneumoniae 183.0 183.0 1 PMID:21616082 -5.1.99.3 (s)-allantoin pseudomonas fluorescens 129.0 129.0 1 PMID:27797489 -5.1.99.4 (2r)-ibuprofenoyl-coa mycobacterium tuberculosis 291.0 259.5 2 PMID:19854148 -5.1.99.4 (2s)-2-methyldecanoyl-coa homo sapiens 0.031 0.031 1 PMID:21614403 -5.1.99.4 (2s)-ibuprofenoyl-coa mycobacterium tuberculosis 450.0 404.0 2 PMID:19854148 -5.1.99.4 (r)-2-methyldecanoyl-coa homo sapiens 53.8 26.915499999999998 2 PMID:19156321;PMID:25277991 -5.1.99.4 (s)-2-methyldecanoyl-coa homo sapiens 60.9 30.485 2 PMID:19156321;PMID:20442897 -5.1.99.4 (s)-ketoprofenoyl-coa homo sapiens 0.015 0.015 1 PMID:21614403 -5.1.99.4 (s)-naproxenoyl-coa homo sapiens 0.0095 0.0095 1 PMID:21614403 -5.1.99.4 3-fluoro-2-methyldecanoyl-coa homo sapiens 0.076 0.076 1 PMID:25277991 -5.1.99.5 d-5-methylthioethylhydantoin agrobacterium tumefaciens 0.5 0.5 1 PMID:15016445 -5.1.99.5 d-benzylhydantoin agrobacterium tumefaciens 0.46 0.46 1 PMID:15016445 -5.1.99.5 d-benzylhydantoin sinorhizobium meliloti 2.29 2.29 1 PMID:14711700 -5.1.99.5 d-ethylhydantoin agrobacterium tumefaciens 1.8 1.8 1 PMID:15016445 -5.1.99.5 d-isobutylhydantoin agrobacterium tumefaciens 0.83 0.83 1 PMID:15016445 -5.1.99.5 d-isobutylhydantoin sinorhizobium meliloti 3.24 3.24 1 PMID:14711700 -5.1.99.5 l-5-methylthioethylhydantoin agrobacterium tumefaciens 0.78 0.78 1 PMID:15016445 -5.1.99.5 l-benzylhydantoin agrobacterium tumefaciens 0.18 0.18 1 PMID:15016445 -5.1.99.5 l-benzylhydantoin sinorhizobium meliloti 1.94 1.94 1 PMID:14711700 -5.1.99.5 l-ethylhydantoin agrobacterium tumefaciens 1.81 1.81 1 PMID:15016445 -5.1.99.5 l-ethylhydantoin sinorhizobium meliloti 6.42 6.42 1 PMID:14711700 -5.1.99.5 l-isobutylhydantoin agrobacterium tumefaciens 0.48 0.48 1 PMID:15016445 -5.1.99.5 l-isobutylhydantoin sinorhizobium meliloti 2.12 2.12 1 PMID:14711700 -5.1.99.6 (6s)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide arabidopsis thaliana 0.38 0.38 1 PMID:24599492 -5.1.99.6 (6s)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate arabidopsis thaliana 0.26 0.26 1 PMID:24599492 -5.1.99.6 (r)-nadh-hydrate mus musculus 82.0 82.0 1 PMID:21994945 -5.1.99.6 (r)-nadph-hydrate mus musculus 1827.0 1827.0 1 PMID:21994945 -5.2.1.1 maleate alcaligenes faecalis 36.7 36.7 1 PMID:9345272 -5.2.1.1 maleate nocardia farcinica 2.8 2.8 1 PMID:20677745 -5.2.1.1 maleate pseudomonas fluorescens 30.0 30.0 1 PMID:5780844 -5.2.1.1 maleate serratia marcescens 0.318 0.318 1 PMID:31324629 -5.2.1.2 (+/-)-2-bromo-3-(4-nitrophenyl)propionic acid homo sapiens 6.08 1.06 6 PMID:12852784 -5.2.1.2 4-maleylacetoacetate homo sapiens 464.0 464.0 1 PMID:12852784 -5.2.1.4 maleylpyruvate ralstonia sp. 101.3 101.3 1 PMID:21672526 -5.2.1.8 n-succinyl-ala-ala-(cis)-pro-phe-4-nitroanilide arabidopsis thaliana 0.036 0.036 1 PMID:26317213 -5.2.1.8 n-succinyl-ala-ala-(cis)-pro-phe-4-nitroanilide corynebacterium glutamicum 172.0 172.0 1 PMID:26341203 -5.2.1.8 n-succinyl-ala-ala-(cis)-pro-phe-4-nitroanilide homo sapiens 34.2 34.2 1 PMID:26020957 -5.2.1.8 n-succinyl-ala-glu-(trans)-pro-phe-4-nitroanilide homo sapiens 140.0 140.0 1 PMID:17113106 -5.2.1.8 n-succinyl-ala-leu-(cis)-pro-phe-4-nitroanilide corynebacterium glutamicum 58.0 58.0 1 PMID:26341203 -5.2.1.8 rnase t1 mycoplasmoides genitalium 0.45 0.45 1 PMID:9533890 -5.2.1.8 succinyl-ala-ala-(cis)-pro-lys-4-methylcoumarin-7-amide oryctolagus cuniculus 0.1 0.065 2 PMID:16380387 -5.2.1.8 succinyl-ala-ala-(cis)-pro-lys-4-methylcoumarin-7-amide saccharomyces cerevisiae 0.05 0.04 2 PMID:16380387 -5.2.1.8 succinyl-ala-ala-(cis)-pro-phe 4-methylcoumarin 7-amide oryctolagus cuniculus 0.19 0.11 2 PMID:16380387 -5.2.1.8 succinyl-ala-ala-(cis)-pro-phe 4-methylcoumarin 7-amide saccharomyces cerevisiae 0.07 0.045000000000000005 2 PMID:16380387 -5.2.1.8 succinyl-ala-ala-pro-phe 4-nitroanilide homo sapiens 14600.0 8040.0 2 PMID:8898384 -5.2.1.8 succinyl-ala-ala-pro-phe 4-nitroanilide legionella pneumophila 1820.0 1820.0 1 PMID:8898384 -5.2.1.8 succinyl-ala-lys-pro-phe-4-nitroanilide legionella pneumophila 1060.0 1060.0 1 PMID:8898384 -5.2.1.8 trywnakmk-(cis)-pfifga thermus thermophilus 70000.0 70000.0 1 PMID:27664121 -5.3.1.1 d-glyceraldehyde 3-phosphate arabidopsis thaliana 3406.0 3406.0 1 PMID:28066493 -5.3.1.1 d-glyceraldehyde 3-phosphate chlamydomonas reinhardtii 3372.0 3372.0 1 PMID:24157611 -5.3.1.1 d-glyceraldehyde 3-phosphate escherichia coli 9000.0 9000.0 1 PMID:9442062 -5.3.1.1 d-glyceraldehyde 3-phosphate gallus gallus 4300.0 3200.0 3 PMID:15350130;PMID:23909928;PMID:24825099 -5.3.1.1 d-glyceraldehyde 3-phosphate giardia duodenalis 7666.0 3166.0 5 PMID:15146481;PMID:18077010;PMID:18620084 -5.3.1.1 d-glyceraldehyde 3-phosphate helicobacter pylori 1470.0 1470.0 1 PMID:17957775 -5.3.1.1 d-glyceraldehyde 3-phosphate leishmania mexicana 4170.0 4085.0 2 PMID:8125090 -5.3.1.1 d-glyceraldehyde 3-phosphate moritella marina 7000.0 7000.0 2 PMID:9442062 -5.3.1.1 d-glyceraldehyde 3-phosphate mycobacterium tuberculosis 68330.0 68330.0 1 PMID:16978361 -5.3.1.1 d-glyceraldehyde 3-phosphate oryctolagus cuniculus 8670.0 8670.0 1 * -5.3.1.1 d-glyceraldehyde 3-phosphate plasmodium falciparum 42330.0 4383.5 8 PMID:11457449;PMID:19622869;PMID:21289039;PMID:21447068;PMID:21671330;PMID:26206206;PMID:26762569 -5.3.1.1 d-glyceraldehyde 3-phosphate pyrococcus furiosus 1548000.0 1548000.0 1 PMID:25824038 -5.3.1.1 d-glyceraldehyde 3-phosphate saccharomyces cerevisiae 16700.0 7300.0 7 PMID:15023076;PMID:18300228;PMID:18439027;PMID:20481463;PMID:21839742;PMID:26570983 -5.3.1.1 d-glyceraldehyde 3-phosphate tenebrio molitor 4300.0 4300.0 1 PMID:19849721 -5.3.1.1 d-glyceraldehyde 3-phosphate thermococcus onnurineus 1430000.0 1430000.0 1 PMID:25824038 -5.3.1.1 d-glyceraldehyde 3-phosphate trichomonas vaginalis 1373.0 1351.5 2 PMID:26618356;PMID:28803140 -5.3.1.1 d-glyceraldehyde 3-phosphate trypanosoma brucei 6170.0 4700.0 12 PMID:11914068;PMID:11997014;PMID:17176070;PMID:17221869;PMID:18219118;PMID:18298085;PMID:21533154;PMID:3311744;PMID:8436128 -5.3.1.1 d-glyceraldehyde 3-phosphate trypanosoma brucei brucei 6000.0 2100.0 4 PMID:21553855;PMID:21939233;PMID:23909928;PMID:27733588 -5.3.1.1 d-glyceraldehyde 3-phosphate trypanosoma cruzi 5167.0 4750.0 4 PMID:17221869;PMID:21533154;PMID:27733588 -5.3.1.1 dihydroxyacetone 3-phosphate gallus gallus 340.0 340.0 1 PMID:24825099 -5.3.1.1 dihydroxyacetone 3-phosphate saccharomyces cerevisiae 860.0 593.5 2 PMID:21839742;PMID:26570983 -5.3.1.1 dihydroxyacetone phosphate gallus gallus 430.0 385.0 2 PMID:15350130;PMID:23909928 -5.3.1.1 dihydroxyacetone phosphate giardia duodenalis 267.0 267.0 1 PMID:15146481 -5.3.1.1 dihydroxyacetone phosphate mycobacterium tuberculosis 730.0 730.0 1 PMID:22120738 -5.3.1.1 dihydroxyacetone phosphate saccharomyces cerevisiae 500.0 500.0 1 PMID:15023076 -5.3.1.1 dihydroxyacetone phosphate trypanosoma brucei 800.0 645.0 3 PMID:17176070;PMID:18219118 -5.3.1.1 dihydroxyacetone phosphate trypanosoma brucei brucei 300.0 300.0 3 PMID:21553855;PMID:21939233;PMID:23909928 -5.3.1.1 glycerone phosphate leishmania mexicana 367.0 367.0 1 PMID:8125090 -5.3.1.1 glycerone phosphate trypanosoma brucei 1080.0 1000.0 3 PMID:11997014;PMID:3311744;PMID:8436128 -5.3.1.12 d-galacturonate halalkalibacterium halodurans 2.4 2.4 1 PMID:18171028 -5.3.1.12 d-glucuronate escherichia coli 196.0 196.0 1 PMID:19678710 -5.3.1.12 d-glucuronate halalkalibacterium halodurans 5.2 5.2 1 PMID:18171028 -5.3.1.13 d-arabinose 5-phosphate bacteroides fragilis 253.0 253.0 1 PMID:24891442 -5.3.1.13 d-arabinose 5-phosphate clostridium tetani 102.0 102.0 1 PMID:28630128 -5.3.1.13 d-arabinose 5-phosphate escherichia coli 218.0 86.9 4 PMID:12805358;PMID:15491279;PMID:16199563;PMID:21498648 -5.3.1.13 d-arabinose 5-phosphate francisella tularensis 141.0 141.0 1 PMID:21236668 -5.3.1.13 d-ribulose 5-phosphate bacteroides fragilis 18.5 18.5 1 PMID:24891442 -5.3.1.13 d-ribulose 5-phosphate clostridium tetani 86.7 86.7 1 PMID:28630128 -5.3.1.13 d-ribulose 5-phosphate escherichia coli 255.0 130.5 4 PMID:12805358;PMID:15491279;PMID:16199563;PMID:21498648 -5.3.1.14 d-allose aeribacillus pallidus 14.2 14.2 1 PMID:17653540 -5.3.1.14 d-allose bacillus subtilis 0.74 0.74 1 * -5.3.1.14 d-allose caldicellulosiruptor obsidiansis 11.25 11.25 1 PMID:28960307 -5.3.1.14 d-allose caldicellulosiruptor saccharolyticus 68.1 68.1 1 PMID:21761877 -5.3.1.14 d-allose dictyoglomus turgidum 81.0 81.0 1 PMID:23070627 -5.3.1.14 d-allose mesorhizobium loti 1.3 1.3 1 PMID:21597169 -5.3.1.14 d-allose stutzerimonas stutzeri 2500.0 21.2 3 PMID:15342115;PMID:20977999;PMID:23772372 -5.3.1.14 d-allose thermoanaerobacterium saccharolyticum 33.9 33.9 1 PMID:20822145 -5.3.1.14 d-allose thermoclostridium stercorarium 27.2 27.2 1 PMID:29124517 -5.3.1.14 d-allulose thermoclostridium stercorarium 36.3 36.3 1 PMID:29124517 -5.3.1.14 d-altrose stutzerimonas stutzeri 0.05 0.05 1 PMID:15342115 -5.3.1.14 d-arabinose stutzerimonas stutzeri 0.17 0.17 1 PMID:15342115 -5.3.1.14 d-glucose stutzerimonas stutzeri 0.024 0.024 1 PMID:15342115 -5.3.1.14 d-ribose aeribacillus pallidus 34.5 34.5 1 PMID:17653540 -5.3.1.14 d-ribose bacillus subtilis 30.7 30.7 1 * -5.3.1.14 d-ribose caldicellulosiruptor saccharolyticus 118.0 118.0 1 PMID:21761877 -5.3.1.14 d-ribose dictyoglomus turgidum 49.0 49.0 1 PMID:23070627 -5.3.1.14 d-ribose mesorhizobium loti 0.1 0.1 1 PMID:21597169 -5.3.1.14 d-ribose stutzerimonas stutzeri 3150.0 1580.7 2 PMID:15342115;PMID:20977999 -5.3.1.14 d-ribose thermoanaerobacterium saccharolyticum 21.5 21.5 1 PMID:20822145 -5.3.1.14 d-xylose stutzerimonas stutzeri 33.0 33.0 1 PMID:15342115 -5.3.1.14 l-fructose caldicellulosiruptor obsidiansis 2.4 2.4 1 PMID:28960307 -5.3.1.14 l-fructose dictyoglomus turgidum 116.0 116.0 1 PMID:23070627 -5.3.1.14 l-fructose thermotoga maritima 274.0 274.0 1 PMID:20809285 -5.3.1.14 l-lyxose aeribacillus pallidus 76.8 76.8 1 PMID:17653540 -5.3.1.14 l-lyxose bacillus subtilis 53.0 53.0 1 * -5.3.1.14 l-lyxose caldicellulosiruptor saccharolyticus 186.0 186.0 1 PMID:21761877 -5.3.1.14 l-lyxose dictyoglomus turgidum 200.0 200.0 1 PMID:23070627 -5.3.1.14 l-lyxose halalkalibacterium halodurans 216.0 216.0 1 PMID:20852996 -5.3.1.14 l-lyxose mesorhizobium loti 73.8 73.8 1 PMID:21597169 -5.3.1.14 l-lyxose stutzerimonas stutzeri 900.0 900.0 1 PMID:15342115 -5.3.1.14 l-lyxose thermoanaerobacterium saccharolyticum 240.0 240.0 1 PMID:20822145 -5.3.1.14 l-lyxose thermotoga maritima 462.0 462.0 1 PMID:20809285 -5.3.1.14 l-mannose aeribacillus pallidus 31.0 31.0 1 PMID:17653540 -5.3.1.14 l-mannose bacillus subtilis 37.0 23.75 2 * -5.3.1.14 l-mannose caldicellulosiruptor obsidiansis 80.4 80.4 1 PMID:28960307 -5.3.1.14 l-mannose caldicellulosiruptor saccharolyticus 78.7 78.7 1 PMID:21761877 -5.3.1.14 l-mannose dictyoglomus turgidum 155.0 155.0 1 PMID:23070627 -5.3.1.14 l-mannose halalkalibacterium halodurans 88.88 88.88 1 PMID:20852996 -5.3.1.14 l-mannose mesorhizobium loti 10.0 10.0 1 PMID:21597169 -5.3.1.14 l-mannose stutzerimonas stutzeri 1000.0 1000.0 1 PMID:15342115 -5.3.1.14 l-mannose thermoanaerobacterium saccharolyticum 30.0 30.0 1 PMID:20822145 -5.3.1.14 l-mannose thermotoga maritima 442.0 442.0 1 PMID:20809285 -5.3.1.14 l-rhamnose aeribacillus pallidus 68.0 68.0 1 PMID:17653540 -5.3.1.14 l-rhamnose bacillus subtilis 153.0 80.35 2 * -5.3.1.14 l-rhamnose caldicellulosiruptor obsidiansis 199.7 199.7 1 PMID:28960307 -5.3.1.14 l-rhamnose caldicellulosiruptor saccharolyticus 99.9 99.9 1 PMID:21761877 -5.3.1.14 l-rhamnose dictyoglomus turgidum 195.0 195.0 1 PMID:23070627 -5.3.1.14 l-rhamnose halalkalibacterium halodurans 149.5 149.5 1 PMID:20852996 -5.3.1.14 l-rhamnose mesorhizobium loti 50.5 50.5 1 PMID:21597169 -5.3.1.14 l-rhamnose stutzerimonas stutzeri 374.0 299.0 2 PMID:20977999;PMID:23772372 -5.3.1.14 l-rhamnose thermoanaerobacterium saccharolyticum 180.0 180.0 1 PMID:20822145 -5.3.1.14 l-rhamnose thermoclostridium stercorarium 202.5 202.5 1 PMID:29124517 -5.3.1.14 l-rhamnose thermotoga maritima 146.0 146.0 1 PMID:20809285 -5.3.1.14 l-rhamnulose stutzerimonas stutzeri 1717.0 1717.0 1 PMID:15342115 -5.3.1.14 l-talose mesorhizobium loti 7.0 7.0 1 PMID:21597169 -5.3.1.14 l-xylose stutzerimonas stutzeri 0.017 0.017 1 PMID:15342115 -5.3.1.14 l-xylulose dictyoglomus turgidum 130.0 130.0 1 PMID:23070627 -5.3.1.14 l-xylulose thermotoga maritima 281.0 281.0 1 PMID:20809285 -5.3.1.15 d-allose paenibacillus baekrokdamisoli 13.79 13.79 1 * -5.3.1.15 d-allulose paenibacillus baekrokdamisoli 6.58 6.58 1 * -5.3.1.15 d-fructose caldanaerobius polysaccharolyticus 0.432 0.432 1 PMID:32527523 -5.3.1.15 d-fructose providencia stuartii 2010.0 2010.0 1 PMID:20541111 -5.3.1.15 d-fructose serratia proteamaculans 4297.0 4297.0 1 PMID:20695994 -5.3.1.15 d-fructose thermoflavimicrobium dichotomicum 13.95 13.95 1 * -5.3.1.15 d-fructose thermoprotei archaeon 24.18 24.18 1 PMID:32750472 -5.3.1.15 d-fructose thermosediminibacter oceani 17.2 17.2 1 * -5.3.1.15 d-lyxose bacillus licheniformis 98.0 98.0 2 PMID:21421786;PMID:29392387 -5.3.1.15 d-lyxose bacillus velezensis 22.27 22.27 1 PMID:31529161 -5.3.1.15 d-lyxose caldanaerobius polysaccharolyticus 14.37 14.37 1 PMID:32527523 -5.3.1.15 d-lyxose cohnella laeviribosi 1902.0 1902.0 1 PMID:29392387 -5.3.1.15 d-lyxose dictyoglomus turgidum 214200.0 107129.75 2 PMID:22350292;PMID:29392387 -5.3.1.15 d-lyxose escherichia coli 13.7 13.7 1 PMID:29392387 -5.3.1.15 d-lyxose providencia stuartii 31340.0 31340.0 2 PMID:20541111;PMID:29392387 -5.3.1.15 d-lyxose serratia proteamaculans 30810.0 30810.0 2 PMID:20695994;PMID:29392387 -5.3.1.15 d-lyxose thermoflavimicrobium dichotomicum 42.76 42.76 1 * -5.3.1.15 d-lyxose thermoprotei archaeon 57.61 57.61 1 PMID:32750472 -5.3.1.15 d-lyxose thermosediminibacter oceani 186480.0 93265.9 2 PMID:29392387 -5.3.1.15 d-mannose bacillus licheniformis 43.0 43.0 1 PMID:21421786 -5.3.1.15 d-mannose bacillus velezensis 20.22 20.22 1 PMID:31529161 -5.3.1.15 d-mannose caldanaerobius polysaccharolyticus 0.992 0.992 1 PMID:32527523 -5.3.1.15 d-mannose dictyoglomus turgidum 2.97 2.97 1 PMID:22350292 -5.3.1.15 d-mannose providencia stuartii 2640.0 2640.0 1 PMID:20541111 -5.3.1.15 d-mannose serratia proteamaculans 16170.0 16170.0 1 PMID:20695994 -5.3.1.15 d-mannose thermoflavimicrobium dichotomicum 52.36 52.36 1 * -5.3.1.15 d-mannose thermoprotei archaeon 46.77 46.77 1 PMID:32750472 -5.3.1.15 d-mannose thermosediminibacter oceani 94.8 94.8 1 * -5.3.1.15 d-xylulose dictyoglomus turgidum 249600.0 124834.65 2 PMID:22350292;PMID:29392387 -5.3.1.15 d-xylulose providencia stuartii 34960.0 34960.0 2 PMID:20541111;PMID:29392387 -5.3.1.15 d-xylulose serratia proteamaculans 31620.0 31620.0 2 PMID:20695994;PMID:29392387 -5.3.1.15 l-ribose bacillus velezensis 16.26 16.26 1 PMID:31529161 -5.3.1.15 l-ribose caldanaerobius polysaccharolyticus 3.03 3.03 1 PMID:32527523 -5.3.1.15 l-ribose thermoflavimicrobium dichotomicum 5.42 5.42 1 * -5.3.1.15 l-ribose thermoprotei archaeon 466.85 466.85 1 PMID:32750472 -5.3.1.15 l-ribulose dictyoglomus turgidum 1.7 1.7 1 PMID:22350292 -5.3.1.16 n'-[(5'-phosphoribosyl)formimino]-5-aminoimidazole-4-carboxamide ribonucleotide escherichia coli 14.3 9.600000000000001 2 PMID:12356303 -5.3.1.16 n'-[(5'-phosphoribosyl)formimino]-5-aminoimidazole-4-carboxamide ribonucleotide thermotoga maritima 32.0 2.94 5 PMID:12356303 -5.3.1.23 5-deoxy-d-ribose methanocaldococcus jannaschii 0.0043 0.0043 1 PMID:29877790 -5.3.1.23 5-deoxy-d-ribose 1-phosphate methanocaldococcus jannaschii 0.067 0.067 1 PMID:29877790 -5.3.1.23 s-methyl-5-thio-alpha-d-ribose 1-phosphate bacillus subtilis 13.0 13.0 1 PMID:17690466 -5.3.1.23 s-methyl-5-thio-alpha-d-ribose 1-phosphate methanocaldococcus jannaschii 0.14 0.14 1 PMID:29877790 -5.3.1.24 n-(5-phospho-beta-d-ribosyl)anthranilate escherichia coli 50.0 40.0 7 PMID:2651124;PMID:3298981;PMID:7727400;PMID:7727401 -5.3.1.24 n-(5-phospho-beta-d-ribosyl)anthranilate saccharomyces cerevisiae 69.0 64.5 2 PMID:3286643;PMID:7727401 -5.3.1.24 n-(5-phospho-beta-d-ribosyl)anthranilate streptomyces coelicolor 12.0 7.7 2 PMID:20066665 -5.3.1.24 n-(5-phospho-beta-d-ribosyl)anthranilate thermotoga maritima 130.0 3.7 7 PMID:10745009;PMID:11265469;PMID:12356303;PMID:22490958;PMID:23109729;PMID:8897600 -5.3.1.25 d-ribulose raoultella sp. 138.0 138.0 1 PMID:33296692 -5.3.1.25 l-fucopyranose caldanaerobius polysaccharolyticus 397.6 397.6 1 PMID:32061850 -5.3.1.25 l-fucose caldanaerobius polysaccharolyticus 397.6 397.6 1 PMID:31778693;PMID:33296692 -5.3.1.25 l-fucose caldicellulosiruptor saccharolyticus 198.7 99.44924999999999 2 PMID:19856146;PMID:33296692 -5.3.1.25 l-fucose dictyoglomus turgidum 258.3 258.3 1 PMID:22627384 -5.3.1.25 l-fucose thermanaeromonas toyohensis 178.13 178.13 1 PMID:33296692 -5.3.1.25 l-fuculose raoultella sp. 113.4 113.4 1 PMID:33296692 -5.3.1.26 d-allose lactococcus lactis 0.16 0.16 1 PMID:21655980 -5.3.1.28 d-sedoheptulose 7-phosphate burkholderia pseudomallei 0.5 0.5 1 PMID:20447408 -5.3.1.28 d-sedoheptulose 7-phosphate escherichia coli 0.44 0.44 1 PMID:18056714 -5.3.1.28 d-sedoheptulose 7-phosphate helicobacter pylori 33.1 33.1 1 PMID:27369071 -5.3.1.28 d-sedoheptulose 7-phosphate mycobacterium tuberculosis 0.45 0.45 1 PMID:33257730 -5.3.1.29 alpha-d-ribose 1,5-bisphosphate thermococcus kodakarensis 29.2 29.2 1 PMID:23065974 -5.3.1.3 d-altrose caldicellulosiruptor saccharolyticus 0.0287 0.0287 1 PMID:19856146 -5.3.1.3 d-altrose thermanaeromonas toyohensis 122.1 122.1 1 PMID:31615684 -5.3.1.3 d-arabinose caldicellulosiruptor saccharolyticus 0.1823 0.1823 1 PMID:19856146 -5.3.1.3 d-arabinose thermanaeromonas toyohensis 307.8 307.8 1 PMID:31615684 -5.3.1.3 l-fucose thermanaeromonas toyohensis 178.1 178.1 1 PMID:31615684 -5.3.1.31 beta-sulfoquinovose escherichia coli 79.0 79.0 1 PMID:33791429 -5.3.1.4 d-galactose [clostridium] hylemonae 28.4 28.4 1 PMID:29684065 -5.3.1.4 d-galactose alicyclobacillus hesperidum 1.13 1.13 1 PMID:26335445 -5.3.1.4 d-galactose anoxybacillus flavithermus 78.5 40.35 2 PMID:21516359 -5.3.1.4 d-galactose escherichia coli 4.21 2.615 2 PMID:18263746 -5.3.1.4 d-galactose geobacillus stearothermophilus 53.08 8.4 5 PMID:15639234;PMID:30282606 -5.3.1.4 d-galactose geobacillus thermodenitrificans 3.4 3.4 1 PMID:16084621 -5.3.1.4 d-galactose halalkalibacterium halodurans 1.2 1.2 1 PMID:15639234 -5.3.1.4 d-galactose lentilactobacillus parabuchneri 0.047 0.047 1 * -5.3.1.4 d-galactose thermoanaerobacterium saccharolyticum 4.9 4.9 1 * -5.3.1.4 d-tagatose escherichia coli 0.82 0.43999999999999995 2 PMID:18263746 -5.3.1.4 l-aldose bacillus subtilis 241.7 241.7 1 PMID:19727704 -5.3.1.4 l-arabinose alicyclobacillus acidocaldarius 33.15 28.55 3 PMID:16332764 -5.3.1.4 l-arabinose alicyclobacillus hesperidum 71.8 71.8 1 PMID:26335445 -5.3.1.4 l-arabinose anoxybacillus flavithermus 0.9 0.9 1 PMID:21516359 -5.3.1.4 l-arabinose bacillus licheniformis 207.6 207.5 3 PMID:18716768;PMID:20048061;PMID:20591668 -5.3.1.4 l-arabinose bacillus velezensis 34.46 34.46 1 PMID:32617845 -5.3.1.4 l-arabinose geobacillus stearothermophilus 107.9 34.1 5 PMID:15639234;PMID:24561191;PMID:30282606 -5.3.1.4 l-arabinose geobacillus thermodenitrificans 113.6 113.6 1 PMID:16084621 -5.3.1.4 l-arabinose halalkalibacterium halodurans 31.03 27.325 4 PMID:15639234;PMID:16332764 -5.3.1.4 l-arabinose heyndrickxia coagulans 3657.0 3657.0 1 PMID:22806043 -5.3.1.4 l-arabinose lentilactobacillus parabuchneri 0.098 0.098 1 * -5.3.1.4 l-arabinose pseudoalteromonas haloplanktis 12.9 12.9 1 PMID:27586234 -5.3.1.4 l-ribulose bacillus subtilis 241.7 241.7 1 PMID:19727704 -5.3.1.5 alpha-d-xylopyranose thermotoga petrophila 68.3 68.3 1 * -5.3.1.5 d-arabinose thermus aquaticus 3.0 3.0 1 PMID:2390219 -5.3.1.5 d-fructose arthrobacter sp. 20.5 11.085 2 PMID:1854338 -5.3.1.5 d-glucose actinoplanes missouriensis 26.3 25.3 3 PMID:15713782;PMID:15848137;PMID:1610791 -5.3.1.5 d-glucose arthrobacter sp. 19.9 11.11 2 PMID:1854338 -5.3.1.5 d-glucose bacillus sp. (in: firmicutes) 50.0 50.0 1 PMID:16349464 -5.3.1.5 d-glucose limosilactobacillus reuteri 15.5 15.5 1 PMID:24443973 -5.3.1.5 d-glucose streptomyces corchorusii 30.72 30.72 1 * -5.3.1.5 d-glucose streptomyces pseudogriseolus 5.27 3.915 4 PMID:9749522 -5.3.1.5 d-glucose thermotoga neapolitana 172.6 79.8 6 PMID:20730758 -5.3.1.5 d-glucose thermotoga petrophila 12.42 12.42 1 * -5.3.1.5 d-glucose thermus aquaticus 3.23 3.23 1 PMID:2390219 -5.3.1.5 d-glucose thermus thermophilus 16.3 8.5665 2 PMID:11784309 -5.3.1.5 d-glucose vibrio sp. 4.54 4.54 1 PMID:21519808 -5.3.1.5 d-glyceraldehyde streptomyces pseudogriseolus 0.0001 0.0001 1 PMID:21995300 -5.3.1.5 d-lyxose arthrobacter sp. 0.0617 0.0617 1 PMID:1854338 -5.3.1.5 d-lyxose thermus thermophilus 25.0 25.0 1 PMID:22586153 -5.3.1.5 d-mannose thermus thermophilus 18.0 18.0 1 PMID:22586153 -5.3.1.5 d-ribose arthrobacter sp. 0.515 0.515 1 PMID:1854338 -5.3.1.5 d-xylose actinoplanes missouriensis 17.3 17.3 1 PMID:1610791 -5.3.1.5 d-xylose arthrobacter sp. 8.88 8.88 1 PMID:1854338 -5.3.1.5 d-xylose bacillus sp. (in: firmicutes) 230.0 230.0 1 PMID:16349464 -5.3.1.5 d-xylose lactococcus lactis 184.0 184.0 1 PMID:15240315 -5.3.1.5 d-xylose limosilactobacillus reuteri 146.6 146.6 1 PMID:24443973 -5.3.1.5 d-xylose streptomyces pseudogriseolus 5.52 0.8 7 PMID:21995300 -5.3.1.5 d-xylose streptomyces violaceoruber 4.15 3.475 2 * -5.3.1.5 d-xylose thermus aquaticus 8.6 5.699999999999999 2 PMID:2390219 -5.3.1.5 d-xylose thermus thermophilus 46.6 46.6 1 PMID:11784309 -5.3.1.5 d-xylose vibrio sp. 47.0 47.0 1 PMID:21519808 -5.3.1.5 d-xylulose thermus aquaticus 7.7 7.7 1 PMID:2390219 -5.3.1.5 l-arabinose actinoplanes missouriensis 0.1 0.1 1 PMID:15713782 -5.3.1.5 l-arabinose arthrobacter sp. 1.31 1.31 1 PMID:1854338 -5.3.1.5 l-arabinose thermus thermophilus 6.5 6.5 1 PMID:22586153 -5.3.1.5 l-ribose actinoplanes missouriensis 0.0252 0.0252 1 PMID:15848137 -5.3.1.6 d-allose acetivibrio thermocellus 2682.0 2682.0 1 PMID:18984017 -5.3.1.6 d-allose brucella anthropi 2859.0 6.1 3 PMID:32100533;PMID:34116752;PMID:35670905 -5.3.1.6 d-allose clostridioides difficile 200.0 200.0 1 PMID:20155483 -5.3.1.6 d-allose thermotoga maritima 140.0 140.0 1 PMID:20155483 -5.3.1.6 d-psicose acetivibrio thermocellus 2347.0 2347.0 2 PMID:18984017;PMID:21132286 -5.3.1.6 d-psicose pseudothermotoga lettingae 0.116 0.116 1 PMID:23386225 -5.3.1.6 d-ribose acetivibrio thermocellus 11880.0 11880.0 1 PMID:18984017 -5.3.1.6 d-ribose clostridioides difficile 160.0 160.0 1 PMID:20155483 -5.3.1.6 d-ribose thermotoga maritima 500.0 500.0 1 PMID:20155483 -5.3.1.6 d-ribose 5-diphosphate trypanosoma cruzi 97.0 54.5 2 PMID:16981853 -5.3.1.6 d-ribose 5-phosphate acetivibrio thermocellus 52000.0 52000.0 2 PMID:18984017 -5.3.1.6 d-ribose 5-phosphate clostridioides difficile 15100.0 15100.0 1 PMID:20155483 -5.3.1.6 d-ribose 5-phosphate escherichia coli 2100.0 2100.0 1 PMID:12517338 -5.3.1.6 d-ribose 5-phosphate leishmania donovani 29.0 29.0 1 PMID:26953696 -5.3.1.6 d-ribose 5-phosphate mycobacterium tuberculosis 120.0 83.5 2 PMID:14687575;PMID:18640127 -5.3.1.6 d-ribose 5-phosphate pyrococcus horikoshii 625.0 472.5 2 PMID:12057201 -5.3.1.6 d-ribose 5-phosphate thermotoga maritima 20000.0 1192.0 3 PMID:20155483;PMID:22333529 -5.3.1.6 d-ribose 5-phosphate thermus thermophilus 1072.0 1071.0 2 PMID:13679361 -5.3.1.6 d-ribose-5-phosphate spinacia oleracea 3440.0 3440.0 1 PMID:10620366 -5.3.1.6 d-ribulose acetivibrio thermocellus 9193.0 9193.0 1 PMID:18984017 -5.3.1.6 d-ribulose 5-diphosphate trypanosoma cruzi 4.7 4.7 1 PMID:16981853 -5.3.1.6 d-ribulose 5-phosphate acetivibrio thermocellus 39530.0 39530.0 2 PMID:18984017 -5.3.1.6 d-ribulose 5-phosphate pyrococcus horikoshii 50.0 50.0 1 PMID:12057201 -5.3.1.6 d-ribulose 5-phosphate trypanosoma cruzi 8.0 8.0 1 PMID:21205211 -5.3.1.6 d-talose acetivibrio thermocellus 119.0 119.0 1 PMID:18984017 -5.3.1.6 l-allose acetivibrio thermocellus 1506.0 1506.0 1 PMID:18984017 -5.3.1.6 l-rhamnose brucella anthropi 129.4 129.4 1 PMID:29913551 -5.3.1.6 l-ribose acetivibrio thermocellus 322.0 322.0 1 PMID:18984017 -5.3.1.6 l-ribulose acetivibrio thermocellus 17.0 17.0 1 PMID:18984017 -5.3.1.6 l-tagatose acetivibrio thermocellus 1822.0 1822.0 1 PMID:18984017 -5.3.1.6 l-talose acetivibrio thermocellus 13420.0 13420.0 1 PMID:18984017 -5.3.1.6 l-talose clostridioides difficile 140.0 140.0 1 PMID:20155483 -5.3.1.6 l-talose thermotoga maritima 1340.0 1340.0 1 PMID:20155483 -5.3.1.7 d-fructose caballeronia jiangsuensis 734.5 734.5 1 * -5.3.1.7 d-fructose deltaproteobacteria bacterium 623.4 623.4 1 * -5.3.1.7 d-fructose escherichia coli 27.7 27.7 1 PMID:27138861 -5.3.1.7 d-fructose pseudomonas syringae 0.581 0.581 1 PMID:33484446 -5.3.1.7 d-fructose stenotrophomonas rhizophila 352.84 352.84 1 PMID:35048315 -5.3.1.7 d-fructose thermosediminibacter oceani 17.2 17.2 1 * -5.3.1.7 d-lyxose caballeronia jiangsuensis 403.7 403.7 1 * -5.3.1.7 d-lyxose deltaproteobacteria bacterium 303.0 303.0 1 * -5.3.1.7 d-lyxose marinomonas mediterranea 64.4 64.4 1 PMID:29107017 -5.3.1.7 d-lyxose stenotrophomonas rhizophila 238.24 238.24 1 PMID:35048315 -5.3.1.7 d-lyxose thermosediminibacter oceani 51.8 51.8 1 * -5.3.1.7 d-mannose caballeronia jiangsuensis 629.3 629.3 1 * -5.3.1.7 d-mannose deltaproteobacteria bacterium 929.6 929.6 1 * -5.3.1.7 d-mannose escherichia coli 40.9 40.9 1 PMID:27138861 -5.3.1.7 d-mannose marinomonas mediterranea 329.0 329.0 1 PMID:29107017 -5.3.1.7 d-mannose pseudomonas syringae 0.766 0.766 1 PMID:33484446 -5.3.1.7 d-mannose stenotrophomonas rhizophila 272.65 272.65 1 PMID:35048315 -5.3.1.7 d-mannose thermosediminibacter oceani 94.8 94.8 1 * -5.3.1.7 d-talose marinomonas mediterranea 0.319 0.319 1 PMID:29107017 -5.3.1.8 beta-d-mannose 6-phosphate escherichia coli 23.0 23.0 1 PMID:21058398 -5.3.1.8 beta-d-mannose 6-phosphate homo sapiens 6.0 6.0 1 PMID:21058398 -5.3.1.8 d-fructose 6-phosphate thermus thermophilus 141.0 141.0 1 PMID:21729734 -5.3.1.8 d-lyxose bacillus subtilis 7089.0 7089.0 1 PMID:19447949 -5.3.1.8 d-mannose bacillus subtilis 3748.0 3748.0 1 PMID:19447949 -5.3.1.8 d-mannose 6-phosphate bacillus amyloliquefaciens 106000.0 106000.0 1 PMID:26171785 -5.3.1.8 d-mannose 6-phosphate burkholderia cepacia 19.4 19.4 1 PMID:17184737 -5.3.1.8 d-mannose 6-phosphate dehalococcoides mccartyi 0.84 0.84 1 PMID:26374290 -5.3.1.8 d-mannose 6-phosphate geobacillus thermodenitrificans 23550.0 23550.0 1 PMID:22447612 -5.3.1.8 d-mannose 6-phosphate pseudomonas aeruginosa 1.38 0.728 2 PMID:15005628;PMID:18801364 -5.3.1.8 d-mannose 6-phosphate saccharomyces cerevisiae 20.0 20.0 1 PMID:15005628 -5.3.1.8 d-mannose 6-phosphate thermus thermophilus 1371.0 1371.0 1 PMID:21729734 -5.3.1.8 d-ribose bacillus subtilis 72.0 72.0 1 PMID:19447949 -5.3.1.8 d-talose bacillus subtilis 63970.0 63970.0 1 PMID:19447949 -5.3.1.8 l-allose bacillus subtilis 920.0 920.0 1 PMID:19447949 -5.3.1.8 l-ribose bacillus subtilis 17600.0 17600.0 1 PMID:19447949 -5.3.1.8 l-ribulose thermus thermophilus 50640.0 50640.0 1 PMID:21115698 -5.3.1.8 mannose 6-phosphate candida albicans 162.0 141.5 2 PMID:7601089 -5.3.1.9 alpha-d-glucose 6-phosphate triticum aestivum 1275.0 699.5 2 PMID:33774822 -5.3.1.9 beta-d-fructose 6-phosphate thermotoga maritima 17.4 17.4 1 PMID:33422670 -5.3.1.9 d-fructose 6-phosphate archaeoglobus fulgidus 32.4 32.4 1 PMID:16336264 -5.3.1.9 d-fructose 6-phosphate carassius auratus 18.0 18.0 1 PMID:19472999 -5.3.1.9 d-fructose 6-phosphate homo sapiens 650.0 650.0 1 PMID:19064002 -5.3.1.9 d-fructose 6-phosphate pyrococcus furiosus 8.4 8.4 1 PMID:16580686 -5.3.1.9 d-fructose 6-phosphate thermococcus kodakarensis 5.0 5.0 1 * -5.3.1.9 d-fructose 6-phosphate thermococcus litoralis 26.0 26.0 1 PMID:12560104 -5.3.1.9 d-glucose 6-phosphate acetivibrio thermocellus 2765.0 1550.0 8 PMID:21630486 -5.3.1.9 d-glucose 6-phosphate homo sapiens 1000.0 750.0 2 PMID:19064002;PMID:21970785 -5.3.1.9 d-glucose 6-phosphate thermococcus litoralis 42.0 42.0 1 PMID:12560104 -5.3.1.9 fructose 6-phosphate homo sapiens 3330.0 3330.0 1 PMID:5135316 -5.3.1.9 l-talose pyrococcus furiosus 475.5 475.5 1 PMID:19159927 -5.3.2.1 (4-hydroxyphenyl)enolpyruvate mycolicibacterium smegmatis 3.2 1.7000000000000002 2 PMID:21370851 -5.3.2.1 (4-hydroxyphenyl)pyruvate sus scrofa 1.89 0.971 2 * -5.3.2.1 cis-3-chloroacrylate mycolicibacterium smegmatis 4.6 4.6 1 PMID:21370851 -5.3.2.1 enol-(p-hydroxyphenyl)pyruvate mus musculus 160.0 160.0 3 PMID:10360941;PMID:10625471;PMID:10933783 -5.3.2.1 enol-phenylpyruvate mus musculus 410.0 290.0 5 PMID:10360941;PMID:10625471;PMID:10933783;PMID:17661448 -5.3.2.1 enol-phenylpyruvate pseudomonas pavonaceae 1.4 1.4 1 PMID:17661448 -5.3.2.1 keto-(p-hydroxyphenyl)pyruvate homo sapiens 2.7 2.7 1 PMID:10353846 -5.3.2.1 keto-(p-hydroxyphenyl)pyruvate mus musculus 120.0 120.0 1 PMID:10360941 -5.3.2.1 keto-phenylpyruvate mus musculus 285.0 285.0 1 PMID:10360941 -5.3.2.1 phenylenolpyruvate mycolicibacterium smegmatis 34.0 17.1 2 PMID:21370851 -5.3.2.1 phenylpyruvate sus scrofa 0.45 0.45 1 * -5.3.2.1 trans-3-chloroacrylate mycolicibacterium smegmatis 0.0004 0.0004 1 PMID:21370851 -5.3.2.2 enol-oxaloacetate bos taurus 45.7 45.0 3 PMID:2624174;PMID:3179281 -5.3.2.2 keto-oxaloacetate bos taurus 3.58 3.58 1 PMID:2624174 -5.3.2.3 dtdp-4-dehydro-6-deoxy-alpha-d-glucose aneurinibacillus thermoaerophilus 10.5 10.5 1 PMID:26125548 -5.3.2.4 cdp-4-dehydro-6-deoxy-alpha-d-glucose streptomyces fradiae 0.00025 0.00025 1 PMID:17209568 -5.3.2.4 dtdp-4-dehydro-2,6-dideoxy-alpha-d-glucose streptomyces fradiae 0.13 0.13 1 PMID:17209568 -5.3.2.4 dtdp-4-dehydro-6-deoxy-alpha-d-glucopyranose streptomyces fradiae 0.1 0.1 1 PMID:17209568 -5.3.2.5 5-(methylthio)-2,3-dioxopentyl 1-phosphate bacillus subtilis 83.0 83.0 1 PMID:20060808 -5.3.2.6 (2e)-2-hydroxy-3-phenylprop-2-enoate pseudomonas putida 16.0 16.0 1 PMID:21809870 -5.3.2.6 (2z,4e)-2-hydroxyhexa-2,4-dienedioate archaeoglobus fulgidus 0.2 0.125 2 PMID:20709352 -5.3.2.6 (2z,4e)-2-hydroxyhexa-2,4-dienedioate helicobacter pylori 0.6 0.6 2 PMID:20709352 -5.3.2.6 (2z,4e)-2-hydroxyhexa-2,4-dienedioate pseudomonas putida 1330.0 1330.0 1 PMID:25161874 -5.3.2.6 2,3-butadienoate gammaproteobacteria bacterium 1.09 1.09 1 PMID:34019384 -5.3.2.6 2-hydroxy-2,4-hexadienedioate chloroflexus aurantiacus 3000.0 3000.0 1 PMID:20465238 -5.3.2.6 2-hydroxy-2,4-hexadienedioate pseudomonas putida 3500.0 3500.0 1 PMID:10493802 -5.3.2.6 2-hydroxy-2,4-pentadienoate archaeoglobus fulgidus 0.1 0.1 1 PMID:20709352 -5.3.2.6 2-hydroxy-2,4-pentadienoate burkholderia lata 170.0 170.0 1 PMID:31074977 -5.3.2.6 2-hydroxy-2,4-pentadienoate helicobacter pylori 2.5 2.5 1 PMID:20709352 -5.3.2.6 2-hydroxy-2,4-pentadienoate pseudomonas putida 0.4 0.4 1 PMID:10493802 -5.3.2.6 2-hydroxymuconate burkholderia lata 580.0 580.0 1 PMID:31074977 -5.3.2.6 2-hydroxymuconate gammaproteobacteria bacterium 0.48 0.48 1 PMID:34019384 -5.3.2.6 2-hydroxymuconate methylibium petroleiphilum 4600.0 2309.25 2 PMID:23831510 -5.3.2.6 2-hydroxymuconate pseudomonas putida 139000.0 3500.0 3 PMID:16784221;PMID:21809870 -5.3.2.6 2-oxo-3-hexenedioate pseudomonas putida 288000.0 288000.0 1 * -5.3.2.6 2-oxo-4(e)-hexenedioate pseudomonas putida 2940.0 2915.0 2 * -5.3.2.6 5-(methyl)-2-hydroxymuconate burkholderia lata 72.0 72.0 1 PMID:31074977 -5.3.2.6 5-(methyl)-2-hydroxymuconate methylibium petroleiphilum 107.0 55.2 2 PMID:23831510 -5.3.2.6 phenylenolpyruvate archaeoglobus fulgidus 2.4 2.4 1 PMID:20709352 -5.3.2.6 phenylenolpyruvate burkholderia lata 136.0 136.0 1 PMID:31074977 -5.3.2.6 phenylenolpyruvate chloroflexus aurantiacus 13.0 13.0 1 PMID:20465238 -5.3.2.6 phenylenolpyruvate helicobacter pylori 2.6 2.6 1 PMID:20709352 -5.3.2.6 propiolate gammaproteobacteria bacterium 1.2 1.2 1 PMID:34019384 -5.3.3.1 17beta-hydroxy-5(10)-estren-3-one comamonas testosteroni 70.8 70.8 1 PMID:14454546 -5.3.3.1 5(10)-estrene-3,17-dione pseudomonas putida 11.1 11.1 1 PMID:10529226 -5.3.3.1 5-androstene-3,17-dione comamonas testosteroni 288000.0 31700.0 3 PMID:12734184;PMID:14454546 -5.3.3.1 5-androstene-3,17-dione homo sapiens 13.6 3.455 4 PMID:12832414;PMID:18524572 -5.3.3.1 5-androstene-3,17-dione pseudomonas putida 27900.0 21200.0 7 PMID:10529226;PMID:10653633;PMID:11389596;PMID:12944376;PMID:15819891;PMID:25947291 -5.3.3.1 dehydroepiandrosterone homo sapiens 4890.0 3951.0 2 PMID:15797861 -5.3.3.1 delta5-pregnen-3,20-dione bos taurus 0.303 0.303 1 PMID:10704908 -5.3.3.13 (5z,8z,11z,14z,17z)-eicosapentaenoate ptilota filicina 41.0 26.3 2 PMID:7803384;PMID:9062129 -5.3.3.13 linoleic acid cutibacterium acnes 4.37 4.37 1 PMID:19164287 -5.3.3.14 cis-3-decenoyl-n-acetylcysteamine escherichia coli 15.0 15.0 1 PMID:4900506 -5.3.3.19 3-[(4s)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate bacillus subtilis 24.52 24.52 1 PMID:19776011 -5.3.3.2 isopentenyl diphosphate methanocaldococcus jannaschii 191.0 191.0 1 PMID:16793276 -5.3.3.2 isopentenyl diphosphate methanothermobacter thermautotrophicus 1.6 1.6 1 PMID:14996812 -5.3.3.2 isopentenyl diphosphate saccharolobus shibatae 29900.0 0.2 3 PMID:15009187;PMID:22158896 -5.3.3.2 isopentenyl diphosphate saccharomyces cerevisiae 8.27 8.27 1 PMID:29712558 -5.3.3.2 isopentenyl diphosphate staphylococcus aureus 0.69 0.57 3 PMID:17585782 -5.3.3.2 isopentenyl diphosphate streptococcus pneumoniae 0.983 0.875 3 PMID:24910111;PMID:27379573 -5.3.3.2 isopentenyl diphosphate thermus thermophilus 17.9 17.9 1 PMID:17428035 -5.3.3.4 (4r,5r)-5-chloro-3-methylmuconolactone cupriavidus necator 42.5 42.5 1 PMID:12218027 -5.3.3.4 (4r,5r/4s,5s)-(+/-)-5-chloro-3-methylmuconolactone cupriavidus necator 267.0 154.75 2 PMID:8647072;PMID:9211711 -5.3.3.4 (4r,5s)-(+)-5-chloromuconolactone cupriavidus necator 5950.0 3133.5 2 PMID:8647072;PMID:9211711 -5.3.3.4 (4r,5s)-5-chloromuconolactone cupriavidus necator 5950.0 5950.0 1 PMID:12218027 -5.3.3.4 (4s)-(+)-muconolactone cupriavidus necator 683.0 525.0 2 PMID:8647072;PMID:9211711 -5.3.3.4 (4s)-2-chloromuconolactone cupriavidus necator 7.17 3.86 2 PMID:12218027 -5.3.3.4 (4s)-muconolactone cupriavidus necator 286.0 286.0 1 PMID:12218027 -5.3.3.4 muconolactone rhodococcus sp. (in: high g+c gram-positive bacteria) 66.67 66.67 1 PMID:16156722 -5.3.3.5 zymosterol homo sapiens 0.423 0.423 1 PMID:12133002 -5.3.3.6 itaconate eubacterium barkeri 2.0 2.0 1 PMID:19559030 -5.3.3.6 methylitaconate eubacterium barkeri 1720.0 1720.0 1 PMID:19559030 -5.3.3.7 cis-aconitate pseudomonas sp. wu-0701 4500.0 4500.0 1 PMID:26293748 -5.3.3.7 trans-aconitate pseudomonas sp. wu-0701 15000.0 15000.0 1 PMID:26293748 -5.3.3.8 2-trans,5-cis-octadienoyl-coa rattus norvegicus 45.0 26.0 3 PMID:11781327 -5.3.3.8 2-trans,5-cis-tetradecadienoyl-coa rattus norvegicus 15.0 12.0 3 PMID:11781327 -5.3.3.8 3-cis-dodecenoyl-coa bos taurus 128.0 128.0 1 PMID:2222859 -5.3.3.8 3-cis-hexenoyl-coa rattus norvegicus 200.0 58.0 3 PMID:11781327 -5.3.3.8 3-cis-hexenoyl-coa sus scrofa 9.4 6.7 2 PMID:376522 -5.3.3.8 3-cis-octenoyl-coa rattus norvegicus 180.0 47.0 3 PMID:11781327 -5.3.3.8 3-cis-tetradecenoyl-coa escherichia coli 63.0 63.0 1 PMID:7756275 -5.3.3.8 3-cis-tetradecenoyl-coa rattus norvegicus 210.0 98.0 3 PMID:11781327 -5.3.3.8 3-decynoyl-n-acetylcysteamine sus scrofa 284.0 128.0 5 PMID:376522 -5.3.3.8 3-dodecynoyl-n-acetylcysteamine sus scrofa 500.0 160.0 3 PMID:376522 -5.3.3.8 3-hexynoyl-coa sus scrofa 25.0 18.55 2 PMID:376522 -5.3.3.8 3-hexynoyl-n-acetylcysteamine sus scrofa 130.0 61.0 3 PMID:376522 -5.3.3.8 3-octynoyl-n-acetylcysteamine sus scrofa 105.0 105.0 1 PMID:376522 -5.3.3.8 3-trans-decenoyl-coa homo sapiens 56.3 56.3 1 PMID:25515061 -5.3.3.8 3-trans-decenoyl-coa saccharomyces cerevisiae 4.4 4.4 1 PMID:26527136 -5.3.3.8 3-trans-hexenoyl-coa homo sapiens 20.2 20.2 1 PMID:25515061 -5.3.3.8 3-trans-hexenoyl-coa rattus norvegicus 270.0 130.0 4 PMID:11781327;PMID:16952422 -5.3.3.8 3-trans-hexenoyl-coa saccharomyces cerevisiae 1.7 1.7 1 PMID:26527136 -5.3.3.8 3-trans-hexenoyl-coa sus scrofa 5.0 4.0 2 PMID:376522 -5.3.3.8 3-trans-octenoyl-coa rattus norvegicus 210.0 25.0 3 PMID:11781327 -5.3.3.8 3-trans-tetradecenoyl-coa rattus norvegicus 540.0 20.0 3 PMID:11781327 -5.3.3.8 trans-3-hexenoyl-coa rattus norvegicus 160.0 160.0 1 PMID:16952422 -5.3.3.8 trans-3-hexenoyl-coa saccharomyces cerevisiae 6.5 3.305 2 PMID:14741345 -5.3.4.1 mycothiol-coupled hydroxyethyl disulfide corynebacterium glutamicum 8.55 8.55 1 PMID:34290951 -5.3.4.1 rnase homo sapiens 0.0011 0.000564 2 PMID:10066758 -5.3.4.1 srnase homo sapiens 0.017 0.017 1 PMID:12486139 -5.3.99.2 (5z,13e)-(15s)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate mus musculus 0.95 0.5 3 PMID:10603301 -5.3.99.2 (5z,13e)-(15s)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate rattus norvegicus 21.7 21.7 1 PMID:10871602 -5.3.99.2 1-chloro-2,4-dinitrobenzene rattus norvegicus 5.0 5.0 1 PMID:10871602 -5.3.99.2 glutathione rattus norvegicus 15.0 8.5 2 PMID:10871602 -5.3.99.2 prostaglandin h2 homo sapiens 2.64 2.64 1 PMID:20667974 -5.3.99.3 (5z,13e)-(15s)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate homo sapiens 50.0 28.5 2 PMID:12460774;PMID:12672824 -5.3.99.3 glutathione homo sapiens 21.0 21.0 1 PMID:12672824 -5.3.99.3 prostaglandin g2 homo sapiens 75.0 75.0 1 PMID:16399384 -5.3.99.3 prostaglandin h2 homo sapiens 50.0 50.0 1 PMID:16399384 -5.3.99.3 prostaglandine g2 homo sapiens 75.0 75.0 1 PMID:12672824 -5.3.99.4 prostaglandin h1 bos taurus 26.5 26.5 1 PMID:8051072 -5.3.99.4 prostaglandin h2 bos taurus 2.45 2.45 1 PMID:8051072 -5.3.99.5 (5z,13e)-(15s)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate homo sapiens 0.017 0.017 1 PMID:11297515 -5.3.99.5 prostaglandin g2 homo sapiens 28.2 28.2 1 PMID:3579292 -5.3.99.5 prostaglandin h2 homo sapiens 27.1 26.9 2 PMID:2999104;PMID:3579292 -5.3.99.5 prostaglandin h3 homo sapiens 59.4 39.9 2 PMID:3579292 -5.4.1.3 2-methylfumaryl-coa chloroflexus aurantiacus 840.0 840.0 1 PMID:19955419 -5.4.2.10 alpha-d-glucosamine 1-phosphate methanococcus maripaludis 0.52 0.52 1 PMID:18263721 -5.4.2.10 alpha-d-glucose 1-phosphate methanococcus maripaludis 0.1 0.1 1 PMID:18263721 -5.4.2.10 d-glucosamine 6-phosphate escherichia coli 7.9 5.16 2 PMID:10231382 -5.4.2.10 d-glucose 1-phosphate escherichia coli 0.0138 0.009649999999999999 2 PMID:10231382 -5.4.2.11 3-phospho-d-glycerate lactococcus lactis subsp. lactis 3200.0 3200.0 1 PMID:20530968 -5.4.2.11 3-phospho-d-glycerate saccharomyces cerevisiae 530.0 530.0 3 PMID:10064712 -5.4.2.11 3-phospho-d-glycerate schizosaccharomyces pombe 82.0 41.01 2 * -5.4.2.11 3-phosphoglycerate saccharomyces cerevisiae 530.0 490.0 3 PMID:10369755;PMID:1386023;PMID:2165932 -5.4.2.12 (2r)-3-phosphoglycerate arabidopsis thaliana 51.3 51.3 1 PMID:34174129 -5.4.2.12 2-phospho-d-glycerate entamoeba histolytica 14.0 10.2 2 PMID:15794763 -5.4.2.12 2-phospho-d-glycerate leishmania mexicana 199.0 199.0 1 PMID:15096219 -5.4.2.12 2-phospho-d-glycerate saccharolobus solfataricus 4.01 2.31 3 * -5.4.2.12 3-phospho-d-glycerate dirofilaria immitis 132.0 132.0 2 PMID:21324604 -5.4.2.12 3-phospho-d-glycerate entamoeba histolytica 57.0 51.0 2 PMID:15794763 -5.4.2.12 3-phospho-d-glycerate leishmania mexicana 434.0 434.0 1 PMID:15096219 -5.4.2.12 3-phospho-d-glycerate saccharolobus solfataricus 3.01 2.18 3 * -5.4.2.12 3-phospho-d-glycerate trypanosoma brucei 3226.0 3226.0 1 PMID:22458781 -5.4.2.12 3-phospho-d-glycerate wolbachia endosymbiont of dirofilaria immitis 102.0 102.0 1 PMID:21324604 -5.4.2.12 3-phospho-d-glycerate wolbachia sp. 102.0 102.0 1 PMID:21324604 -5.4.2.2 alpha-d-glucose 1-phosphate acetivibrio thermocellus 190.0 190.0 1 PMID:19566723 -5.4.2.2 alpha-d-glucose 1-phosphate fusarium oxysporum 0.74 0.74 1 PMID:22112903 -5.4.2.2 alpha-d-glucose 1-phosphate ganoderma lucidum 0.15 0.1275 2 PMID:29349492 -5.4.2.2 alpha-d-glucose 1-phosphate homo sapiens 71.2 71.2 1 PMID:32057119 -5.4.2.2 alpha-d-glucose 1-phosphate komagataeibacter xylinus 135.0 135.0 1 PMID:9337869 -5.4.2.2 alpha-d-glucose 1-phosphate mycobacterium tuberculosis 70.31 70.31 1 PMID:22809717 -5.4.2.2 alpha-d-glucose 1-phosphate pseudomonas aeruginosa 95.0 95.0 1 PMID:23517223 -5.4.2.2 alpha-d-glucose 1-phosphate sphingobium chungbukense 126.8 126.8 1 PMID:18664520 -5.4.2.2 alpha-d-glucose 1-phosphate sphingomonas sanxanigenens 10.77 10.77 1 PMID:23546942 -5.4.2.2 alpha-d-glucose 1-phosphate toxoplasma gondii 398.0 245.5 2 PMID:20153838 -5.4.2.2 alpha-d-mannose 1-phosphate acetivibrio thermocellus 59.0 59.0 1 PMID:19566723 -5.4.2.2 alpha-d-mannose 1-phosphate sphingobium chungbukense 79.17 79.17 1 PMID:18664520 -5.4.2.2 d-glucose 1,6-diphosphate fusarium oxysporum 0.74 0.74 1 PMID:22112903 -5.4.2.2 glucose 1-phosphate pseudomonas aeruginosa 50.0 50.0 1 PMID:8050998 -5.4.2.2 mannose 1-phosphate pseudomonas aeruginosa 22.5 22.5 1 PMID:8050998 -5.4.2.3 alpha-d-glucose 1-phosphate arabidopsis thaliana 40.43 40.43 1 PMID:26788420 -5.4.2.3 n-acetyl-alpha-d-glucosamine homo sapiens 2.94 2.365 2 PMID:11004509 -5.4.2.4 1,3-diphosphoglycerate equus caballus 23.4 12.5 3 PMID:187124 -5.4.2.4 2,3-bisphospho-d-glycerate homo sapiens 1.0 0.007 5 PMID:35362470 -5.4.2.4 2,3-diphosphoglycerate homo sapiens 0.0037 0.0037 1 PMID:9162026 -5.4.2.6 beta-d-glucose 1-phosphate escherichia coli 21.0 21.0 1 PMID:29684280 -5.4.2.6 beta-d-glucose 1-phosphate lactococcus lactis 177.0 40.900000000000006 4 PMID:11807265;PMID:15996095;PMID:16784233;PMID:19132841 -5.4.2.6 beta-d-glucose 1-phosphate lactococcus lactis subsp. lactis 24.5 24.5 1 PMID:35692864 -5.4.2.6 beta-d-glucose 6-phosphate escherichia coli 0.5 0.5 1 PMID:29684280 -5.4.2.6 beta-d-glucose 6-phosphate lactococcus lactis subsp. lactis 382.0 382.0 1 PMID:35692864 -5.4.2.7 2-deoxy-d-ribose 1-phosphate thermococcus kodakarensis 173.0 173.0 1 PMID:15205420 -5.4.2.7 alpha-d-ribose 5-phosphate thermotoga maritima 185.0 120.3 2 PMID:26924489 -5.4.2.7 d-ribose 5-phosphate bacillus cereus 10.2 10.2 1 PMID:21193409 -5.4.2.8 alpha-d-glucose 1-phosphate aspergillus fumigatus 7.4 7.4 1 PMID:33629421 -5.4.2.8 alpha-d-glucose 1-phosphate lactococcus lactis subsp. lactis 44.0 44.0 1 PMID:29952545 -5.4.2.8 alpha-d-glucose 1-phosphate pseudomonas aeruginosa 7.83 7.83 1 PMID:18690721 -5.4.2.8 alpha-d-glucose 1-phosphate sphingobium chungbukense 82.93 82.93 1 PMID:18664520 -5.4.2.8 alpha-d-mannose 1-phosphate arabidopsis thaliana 10.01 7.07 2 PMID:18086684 -5.4.2.8 alpha-d-mannose 1-phosphate aspergillus fumigatus 1.4 1.4 1 PMID:33629421 -5.4.2.8 alpha-d-mannose 1-phosphate sphingobium chungbukense 134.9 134.9 1 PMID:18664520 -5.4.2.8 alpha-d-mannose 1-phosphate sphingomonas sanxanigenens 2.28 2.28 1 PMID:23546942 -5.4.2.8 d-glucose 1-phosphate homo sapiens 2.85 2.85 1 PMID:16540464 -5.4.2.8 d-glucose-1-phosphate homo sapiens 1.72 1.72 1 PMID:16540464 -5.4.2.8 d-mannose 1-phosphate homo sapiens 4.4 4.4 1 PMID:16540464 -5.4.2.8 d-mannose-1-phosphate homo sapiens 3.9 3.9 1 PMID:16540464 -5.4.2.9 3-phosphonopyruvate mytilus edulis 34.0 33.95 2 PMID:15078090;PMID:35943842 -5.4.2.9 phosphonopyruvate tetrahymena pyriformis 150.0 60.0 5 PMID:1547241;PMID:2121271;PMID:3138545;PMID:8180189 -5.4.3.10 3'-methyl-alpha-phenylalanine taxus canadensis 0.022 0.022 1 PMID:21361343 -5.4.3.10 4'-methyl-alpha-phenylalanine taxus canadensis 0.03 0.03 1 PMID:21361343 -5.4.3.10 d-alpha-phenylalanine taxus chinensis 0.0032 0.0032 1 * -5.4.3.10 l-beta-phenylalanine pantoea agglomerans 0.00022 0.00022 1 PMID:31731949 -5.4.3.10 l-beta-phenylalanine taxus chinensis 0.026 0.017599999999999998 2 * -5.4.3.10 l-beta-tyrosine taxus chinensis 0.06 0.06 1 * -5.4.3.10 l-phenylalanine pantoea agglomerans 0.31 0.31 1 PMID:31409485 -5.4.3.10 l-phenylalanine taxus canadensis 0.053 0.053 1 PMID:21361343 -5.4.3.10 l-phenylalanine taxus chinensis 0.02 0.02 1 * -5.4.3.10 l-tyrosine taxus chinensis 0.029 0.029 1 * -5.4.3.10 styryl-alpha-alanine taxus canadensis 0.0002 0.0002 1 PMID:21361343 -5.4.3.10 trans-cinnamic acid pantoea agglomerans 3.1e-05 3.1e-05 1 PMID:31731949 -5.4.3.11 2-fluoro-l-phenylalanine pantoea agglomerans 0.022 0.022 1 * -5.4.3.11 2-methoxy-l-phenylalanine pantoea agglomerans 0.003 0.003 1 * -5.4.3.11 2-methyl-l-phenylalanine pantoea agglomerans 0.064 0.064 1 * -5.4.3.11 3-bromo-l-phenylalanine pantoea agglomerans 0.42 0.42 1 * -5.4.3.11 3-chloro-l-phenylalanine pantoea agglomerans 0.484 0.484 1 * -5.4.3.11 3-fluoro-l-phenylalanine pantoea agglomerans 0.031 0.031 1 * -5.4.3.11 3-furan-2-yl-l-phenylalanine pantoea agglomerans 0.236 0.236 1 * -5.4.3.11 3-methoxy-l-phenylalanine pantoea agglomerans 0.209 0.209 1 * -5.4.3.11 3-methyl-l-phenylalanine pantoea agglomerans 0.058 0.058 1 * -5.4.3.11 3-nitro-l-phenylalanine pantoea agglomerans 0.146 0.146 1 * -5.4.3.11 3-thiophen-2-yl-l-phenylalanine pantoea agglomerans 0.026 0.026 1 * -5.4.3.11 3-thiophen-3-yl-l-phenylalanine pantoea agglomerans 0.143 0.143 1 * -5.4.3.11 4-bromo-l-phenylalanine pantoea agglomerans 0.045 0.045 1 * -5.4.3.11 4-chloro-l-phenylalanine pantoea agglomerans 0.053 0.053 1 * -5.4.3.11 4-fluoro-l-phenylalanine pantoea agglomerans 0.023 0.023 1 * -5.4.3.11 4-methoxy-l-phenylalanine pantoea agglomerans 0.022 0.022 1 * -5.4.3.11 4-methyl-l-phenylalanine pantoea agglomerans 0.013 0.013 1 * -5.4.3.11 4-nitro-l-phenylalanine pantoea agglomerans 0.038 0.038 1 * -5.4.3.11 d-beta-phenylalanine pantoea agglomerans 0.059 0.059 1 PMID:22461423 -5.4.3.11 d-beta-phenylalanine streptomyces maritimus 0.22 0.22 1 PMID:22461423 -5.4.3.11 l-phenylalanine pantoea agglomerans 0.301 0.087 3 PMID:21561099;PMID:22461423 -5.4.3.11 l-phenylalanine streptomyces maritimus 0.159 0.159 1 PMID:22461423 -5.4.3.2 l-lys clostridium subterminale 83.0 83.0 1 PMID:17042480 -5.4.3.2 l-lys escherichia coli 0.083 0.083 1 PMID:17042480 -5.4.3.2 l-lysine methanococcus maripaludis 14.3 14.3 1 PMID:35544775 -5.4.3.3 d-lysine acetoanaerobium sticklandii 14.2 7.6 2 * -5.4.3.5 d-ornithine acetoanaerobium sticklandii 1072.0 2.935 8 PMID:11577113;PMID:21899873;PMID:23311430;PMID:25213862;PMID:25627283;PMID:28528213 -5.4.3.5 dl-ornithine acetoanaerobium sticklandii 2.9 2.9 1 PMID:25100213 -5.4.3.6 l-3,4-dihydroxyphenylalanine streptomyces globisporus 0.0067 0.0067 1 PMID:14580219 -5.4.3.6 l-3-chlorotyrosine streptomyces globisporus 0.0048 0.0048 1 PMID:14580219 -5.4.3.6 l-phenylalanine oryza sativa 0.00016 0.00016 1 PMID:26709535 -5.4.3.6 l-tyrosine chondromyces crocatus 7000.0 0.0072 3 PMID:19222035;PMID:20924508 -5.4.3.6 l-tyrosine cupriavidus crocatus 7000.0 7000.0 1 PMID:20924508 -5.4.3.6 l-tyrosine oryza sativa 0.005 0.005 1 PMID:26709535 -5.4.3.6 l-tyrosine streptomyces globisporus 10000.0 0.01 3 PMID:14580219;PMID:20924508 -5.4.3.8 (s)-4-amino-5-oxopentanoate hordeum vulgare 0.11 0.11 1 PMID:16669079 -5.4.3.8 (s)-4-amino-5-oxopentanoate synechococcus sp. 0.95 0.71 2 PMID:1567858;PMID:1765090 -5.4.4.2 chorismate arabidopsis thaliana 38.1 11.54 4 PMID:17190832;PMID:28356402 -5.4.4.2 chorismate escherichia coli 2.93 1.33 5 PMID:17240978;PMID:20079748;PMID:2139795;PMID:9150206 -5.4.4.2 chorismate pseudomonas aeruginosa 50.4 6.08 3 PMID:12624097;PMID:23942051 -5.4.4.2 isochorismate escherichia coli 1.8 1.8 1 PMID:2139795 -5.4.4.6 (8r,9z,12z)-8-hydroperoxyoctadeca-9,12-dienoate colletotrichum gloeosporioides 10.5 10.5 1 PMID:26577673 -5.4.4.6 alpha-linolenate colletotrichum gloeosporioides 6.58 6.58 1 PMID:26577673 -5.4.4.6 oleate colletotrichum gloeosporioides 5.62 5.62 1 PMID:26577673 -5.4.4.6 palmitoleate colletotrichum gloeosporioides 4.86 4.86 1 PMID:26577673 -5.4.99.1 (2s,3s)-3-methylaspartate clostridium cochlearium 5.8 5.8 1 PMID:9398218 -5.4.99.1 l-2-hydroxyglutarate clostridium cochlearium 0.05 0.05 1 PMID:10956023 -5.4.99.1 l-glu clostridium cochlearium 5.8 5.8 1 PMID:9398218 -5.4.99.1 l-glu clostridium tetanomorphum 20.0 10.325 2 PMID:9003368 -5.4.99.1 l-glutamate clostridium cochlearium 5.8 5.8 2 PMID:11755393;PMID:15023074 -5.4.99.1 l-threo-3-methylaspartate clostridium cochlearium 5.4 5.4 1 PMID:17306212 -5.4.99.11 d-glucose paraburkholderia acidicola 15.0 15.0 1 PMID:19783746 -5.4.99.11 isomaltulose paraburkholderia acidicola 258.0 258.0 1 PMID:19783746 -5.4.99.11 sucrose erwinia sp. ejp617 804.9 766.245 4 PMID:34519920;PMID:35348852 -5.4.99.11 sucrose klebsiella sp. 10430.0 10415.0 2 PMID:12527377 -5.4.99.11 sucrose serratia plymuthica 992.8 992.8 3 PMID:22124943;PMID:26886729 -5.4.99.11 trehalulose paraburkholderia acidicola 1144.0 1144.0 1 PMID:19783746 -5.4.99.12 trna uridine39 escherichia coli 0.73 0.45499999999999996 2 PMID:9425056 -5.4.99.12 trnahis guanidine36 uridine38 cytidine39 escherichia coli 0.0019 0.0019 1 PMID:9174935 -5.4.99.12 trnahis uridine38 cytidine39 escherichia coli 0.0746 0.0746 1 PMID:9174935 -5.4.99.12 trnahis uridine38 uridine39 escherichia coli 0.144 0.144 1 PMID:9174935 -5.4.99.12 trnaval2a cytidine36 uridine38 escherichia coli 0.0244 0.0244 1 PMID:9174935 -5.4.99.13 2-methylpropanoyl-coa cupriavidus metallidurans 48.33 48.33 1 PMID:26134562 -5.4.99.13 butanoyl-coa streptomyces virginiae 38.2 38.2 1 PMID:10531377 -5.4.99.13 isobutyryl-coa geobacillus kaustophilus 3.1 1.96 3 PMID:19864421 -5.4.99.13 isovaleryl-coa cupriavidus metallidurans 0.062 0.062 1 PMID:26134562 -5.4.99.14 (4s)-4-methylmuconolactone pseudomonas reinekei 24.2 24.2 1 PMID:19801657 -5.4.99.14 1-methyl-3,7-dioxo-2,6-dioxabicyclo[3.3.0]octane cupriavidus necator 3.75 3.75 1 PMID:2241929 -5.4.99.14 4-carboxymethyl-4-methylbut-2-en-1,4-olide cupriavidus necator 98.5 98.5 1 PMID:2241929 -5.4.99.15 maltodextrin sulfolobus acidocaldarius 143.45 143.45 1 PMID:32227942 -5.4.99.15 maltoheptaose saccharolobus solfataricus 383.0 383.0 1 PMID:17567140;PMID:19127729 -5.4.99.15 maltohexaose saccharolobus shibatae 33.0 33.0 1 PMID:9827330 -5.4.99.15 maltohexaose saccharolobus solfataricus 359.0 359.0 1 PMID:17567140;PMID:19127729 -5.4.99.15 maltopentaose arthrobacter ramosus 242.7 242.7 1 PMID:31016980 -5.4.99.15 maltopentaose saccharolobus solfataricus 411.0 411.0 3 PMID:17567140;PMID:19127729;PMID:24564903 -5.4.99.15 maltotetraose saccharolobus solfataricus 138.0 138.0 1 PMID:17567140;PMID:19127729 -5.4.99.16 alpha,alpha-trehalose meiothermus ruber 110.0 89.45 2 PMID:22402678 -5.4.99.16 alpha,alpha-trehalose mycolicibacterium smegmatis 66.0 66.0 1 PMID:21840994 -5.4.99.16 alpha,alpha-trehalose thermus antranikianii 64.84 64.84 1 PMID:31711928 -5.4.99.16 maltose deinococcus geothermalis 31.9 31.9 1 * -5.4.99.16 maltose meiothermus ruber 147.0 147.0 1 PMID:22402678 -5.4.99.16 maltose mycolicibacterium smegmatis 19.0 19.0 1 PMID:21840994 -5.4.99.16 maltose picrophilus oshimae 97.8 96.4 2 PMID:16968068 -5.4.99.16 maltose pseudomonas putida 45.5 45.5 1 PMID:31021505 -5.4.99.16 maltose thermus antranikianii 148.04 148.04 1 PMID:31711928 -5.4.99.16 maltose thermus thermophilus 227.0 227.0 1 PMID:22402678 -5.4.99.16 trehalose picrophilus oshimae 187.6 187.6 1 PMID:16968068 -5.4.99.17 squalene alicyclobacillus acidocaldarius 1.98 0.86 3 PMID:15056909;PMID:17017798 -5.4.99.18 5-amino-1-(5-phospho-d-ribosyl)imidazole-4-carboxylate acetobacter aceti 12.2 12.2 1 PMID:16819818 -5.4.99.18 5-amino-1-(5-phospho-d-ribosyl)imidazole-4-carboxylate escherichia coli 15.6 15.6 1 PMID:17298082 -5.4.99.18 5-carboxyamino-1-(5-phospho-d-ribosyl)imidazole escherichia coli 15.5 15.5 1 PMID:17298082 -5.4.99.2 (r)-2-methylmalonyl-coa methylorubrum extorquens 255.0 237.0 3 PMID:16866376 -5.4.99.2 (r)-2-methylmalonyl-coa propionibacterium freudenreichii subsp. shermanii 158.0 96.5 4 PMID:11031263;PMID:11893736;PMID:16503649 -5.4.99.2 (r)-methylmalonyl-coa homo sapiens 3.95 3.95 1 PMID:23311430 -5.4.99.2 (r/s)-2-methyl-3-oxopropanoyl-coa homo sapiens 283.0 216.5 2 PMID:7989334 -5.4.99.2 succinyl-coa propionibacterium freudenreichii subsp. shermanii 48.0 48.0 1 PMID:10924114 -5.4.99.20 23s rrna uridine2457 escherichia coli 1.7 1.7 1 PMID:29555553 -5.4.99.25 trna uridine55 escherichia coli 0.78 0.18 4 PMID:10529181;PMID:10924141;PMID:15987897;PMID:9425055 -5.4.99.25 trna uridine55 thermotoga maritima 0.18 0.18 1 PMID:16300397 -5.4.99.27 trna uridine13 escherichia coli 0.00097 0.00097 1 PMID:19664587 -5.4.99.28 trna uridine32 escherichia coli 0.099 0.099 3 PMID:10529181;PMID:10924141;PMID:17002302 -5.4.99.30 udp-beta-l-arabinofuranose chlamydomonas reinhardtii 5.98 3.71 2 PMID:24018663 -5.4.99.30 udp-beta-l-arabinofuranose oryza sativa 0.474 0.474 2 PMID:20057139 -5.4.99.30 udp-beta-l-arabinopyranose chlamydomonas reinhardtii 1.44 1.185 2 PMID:24018663 -5.4.99.30 udp-beta-l-arabinopyranose oryza sativa 0.185 0.185 2 PMID:20057139 -5.4.99.33 (3s)-2,3-epoxy-2,3-dihydrosqualene siraitia grosvenorii 0.015 0.013999999999999999 2 PMID:30754652 -5.4.99.39 (s)-2,3-oxidosqualene euphorbia tirucalli 0.77 0.77 1 PMID:23294602 -5.4.99.4 (r)-3-[methyl-h3]methylitaconate eubacterium barkeri 1.1 1.1 1 PMID:12440902 -5.4.99.4 (r)-3-methylitaconate eubacterium barkeri 18.0 18.0 1 PMID:12440902 -5.4.99.4 (r,z)-3-[methyl-h3]methyl[2'-h1]itaconate eubacterium barkeri 1.4 1.4 1 PMID:12440902 -5.4.99.4 (r,z)-3-methyl[2'-h1]itaconate eubacterium barkeri 17.0 17.0 1 PMID:12440902 -5.4.99.4 2-methylene[4-h2]glutarate eubacterium barkeri 2.3 2.3 1 PMID:12440902 -5.4.99.4 2-methyleneglutarate eubacterium barkeri 30.0 30.0 1 PMID:12440902 -5.4.99.40 (3s)-2,3-epoxy-2,3-dihydrosqualene eriobotrya japonica 0.24 0.24 1 PMID:30216049 -5.4.99.40 (3s)-2,3-epoxy-2,3-dihydrosqualene malus domestica 0.723 0.723 1 PMID:30216049 -5.4.99.5 chorismate amborella trichopoda 22.8 18.9 2 PMID:28963347 -5.4.99.5 chorismate arabidopsis thaliana 39.0 16.05 6 PMID:25160622;PMID:28963347 -5.4.99.5 chorismate aspergillus nidulans 92.0 87.0 2 PMID:10428795 -5.4.99.5 chorismate bacillus subtilis 50.0 46.0 6 PMID:10960481;PMID:11087356;PMID:12733875;PMID:2105742;PMID:28743924 -5.4.99.5 chorismate corynebacterium glutamicum 1.05 1.05 1 PMID:19589834 -5.4.99.5 chorismate escherichia coli 366000.0 148900.0 19 PMID:12733875;PMID:12818673;PMID:15820980;PMID:8831972;PMID:9497350;PMID:9843375 -5.4.99.5 chorismate methanocaldococcus jannaschii 5.7 4.35 2 PMID:19053245;PMID:9665711 -5.4.99.5 chorismate mycobacterium tuberculosis 60.0 38.0 8 PMID:15654876;PMID:15737998;PMID:17146044;PMID:18727669;PMID:19556970;PMID:28202315;PMID:36705397 -5.4.99.5 chorismate ogataea angusta 367.0 89.3 3 PMID:10894726 -5.4.99.5 chorismate physcomitrium patens 20.7 20.1 2 PMID:28963347 -5.4.99.5 chorismate saccharomyces cerevisiae 361.0 361.0 1 PMID:9501182 -5.4.99.5 chorismate selaginella moellendorffii 18.8 18.8 1 PMID:28963347 -5.4.99.5 chorismate thermus thermophilus 52.0 52.0 1 PMID:14727008 -5.4.99.5 chorismate yersinia pestis 70.0 70.0 1 PMID:18727669 -5.4.99.5 prephenate escherichia coli 94140.0 94120.0 2 PMID:12818673 -5.4.99.59 dtdp-alpha-d-fucopyranose escherichia coli 0.056 0.056 1 PMID:19019146 -5.4.99.61 precorrin-8x pseudomonas denitrificans (nom. rej.) 0.00142 0.00142 1 PMID:1732194 -5.4.99.64 (r)-3-hydroxybutanoyl-coa aquincola tertiaricarbonis 0.0033 0.00315 2 PMID:22433853;PMID:25720495 -5.4.99.64 (r)-3-hydroxybutanoyl-coa kyrpidia tusciae dsm 2912 4.9 4.9 1 PMID:25911482 -5.4.99.64 (s)-3-hydroxybutanoyl-coa aquincola tertiaricarbonis 0.2 0.2 2 PMID:22433853;PMID:25720495 -5.4.99.64 (s)-3-hydroxybutanoyl-coa kyrpidia tusciae dsm 2912 1.6 1.6 1 PMID:25911482 -5.4.99.64 2,2-dimethylpropanoyl-coa aquincola tertiaricarbonis 0.016 0.016 1 PMID:25720495 -5.4.99.64 2-hydroxy-2-methylpropanoyl-coa aquincola tertiaricarbonis 0.05 0.05 2 PMID:22433853;PMID:25720495 -5.4.99.64 2-hydroxyisobutanoyl-coa kyrpidia tusciae dsm 2912 3.7 3.7 1 PMID:25911482 -5.4.99.64 butanoyl-coa aquincola tertiaricarbonis 0.0033 0.0033 1 PMID:22433853 -5.4.99.64 isobutanoyl-coa aquincola tertiaricarbonis 0.001 0.001 1 PMID:22433853 -5.4.99.64 isovaleryl-coa aquincola tertiaricarbonis 0.011 0.011 1 PMID:25720495 -5.4.99.9 udp-(6-deoxy-6-fluoro)-d-galactofuranose escherichia coli 7.4 7.4 1 PMID:19119008 -5.4.99.9 udp-(6-deoxy-6-fluoro)-d-galactofuranose mycobacterium tuberculosis 7.4 7.4 1 PMID:19119008 -5.4.99.9 udp-2-amino-2-deoxy-d-galactopyranose klebsiella pneumoniae 1.4 1.4 1 PMID:19225684 -5.4.99.9 udp-2-deoxy-2-fluoro-d-galactofuranose escherichia coli 0.033 0.033 1 PMID:19119008 -5.4.99.9 udp-2-deoxy-2-fluoro-d-galactopyranose klebsiella pneumoniae 0.0007 0.0007 1 PMID:19225684 -5.4.99.9 udp-2-fluoro-galactofuranose mycobacterium tuberculosis 0.033 0.033 1 PMID:19119008 -5.4.99.9 udp-3-deoxy-3-fluoro-d-galactofuranose escherichia coli 5.7 5.7 1 PMID:19119008 -5.4.99.9 udp-3-deoxy-3-fluoro-d-galactofuranose mycobacterium tuberculosis 5.7 5.7 1 PMID:19119008 -5.4.99.9 udp-3-deoxy-3-fluoro-d-galactopyranose klebsiella pneumoniae 0.9 0.9 1 PMID:19225684 -5.4.99.9 udp-6-deoxy-6-fluoro-d-galactopyranose klebsiella pneumoniae 3.5 3.5 1 PMID:19225684 -5.4.99.9 udp-6-deoxy-d-galactopyranose klebsiella pneumoniae 42.2 42.2 1 PMID:19225684 -5.4.99.9 udp-alpha-d-galactofuranose aspergillus fumigatus 100.0 86.0 2 PMID:25412209;PMID:29757624 -5.4.99.9 udp-alpha-d-galactofuranose mycobacterium tuberculosis 71.0 39.4 2 PMID:25412209;PMID:35215309 -5.4.99.9 udp-alpha-d-galactofuranose trypanosoma cruzi 13.4 13.4 1 PMID:25412209 -5.4.99.9 udp-alpha-d-galactopyranose aspergillus fumigatus 8.72 8.72 1 PMID:22334662 -5.4.99.9 udp-alpha-d-galactopyranose trypanosoma cruzi 13.4 13.4 1 PMID:23934860 -5.4.99.9 udp-beta-l-arabinofuranose aspergillus fumigatus 0.14 0.14 1 PMID:29757624 -5.4.99.9 udp-d-galactofuranose aspergillus fumigatus 72.0 72.0 1 PMID:20615386 -5.4.99.9 udp-d-galactofuranose escherichia coli 27.0 14.25 2 * -5.4.99.9 udp-d-galactofuranose klebsiella pneumoniae 36.8 36.8 1 PMID:19225684 -5.4.99.9 udp-d-galactofuranose leishmania major 5.0 5.0 1 PMID:21419104 -5.4.99.9 udp-d-galactopyranose klebsiella pneumoniae 35.3 20.4 2 PMID:17511471;PMID:19225684 -5.4.99.9 udp-galactofuranose mycobacterium tuberculosis 27.0 27.0 1 PMID:19119008 -5.4.99.9 udp-galactopyranose deinococcus radiodurans 66.0 66.0 1 PMID:19836401 -5.4.99.9 udp-galactopyranose escherichia coli 27.0 27.0 1 PMID:19119008 -5.4.99.9 udp-l-arabinofuranose escherichia coli 12.0 12.0 1 PMID:19119008 -5.5.1.1 2,4-dichloro-cis,cis-muconate pseudomonas putida 198.0 198.0 1 PMID:9726873 -5.5.1.1 2-chloro-cis,cis-muconate acinetobacter calcoaceticus 1020.0 1020.0 1 PMID:9726873 -5.5.1.1 2-chloro-cis,cis-muconate pseudomonas putida 2940.0 2940.0 1 PMID:9726873 -5.5.1.1 2-chloro-cis,cis-muconate rhodococcus erythropolis 3.6 3.6 1 PMID:7751292 -5.5.1.1 2-methyl-cis,cis-muconate acinetobacter calcoaceticus 202000.0 202000.0 1 PMID:9726873 -5.5.1.1 2-methyl-cis,cis-muconate pseudomonas putida 234000.0 234000.0 1 PMID:9726873 -5.5.1.1 2-methyl-cis,cis-muconate pseudomonas sp. 6.0 6.0 1 PMID:17172348 -5.5.1.1 2-methylmuconate pseudomonas reinekei 0.5 0.5 1 PMID:19465655 -5.5.1.1 3-chloro-cis,cis-muconate pseudomonas putida 3840.0 3840.0 1 PMID:9726873 -5.5.1.1 3-chloro-cis,cis-muconate pseudomonas reinekei 120.0 120.0 1 PMID:17172348 -5.5.1.1 3-chloro-cis,cis-muconate pseudomonas sp. 14.4 14.4 1 PMID:17172348 -5.5.1.1 3-chloro-cis,cis-muconate rhodococcus erythropolis 8.8 8.8 1 PMID:7751292 -5.5.1.1 3-chloromuconate pseudomonas reinekei 111.0 111.0 1 PMID:19465655 -5.5.1.1 3-fluoro-cis,cis-muconate acinetobacter calcoaceticus 156000.0 156000.0 1 PMID:9726873 -5.5.1.1 3-fluoro-cis,cis-muconate pseudomonas putida 534000.0 534000.0 1 PMID:9726873 -5.5.1.1 3-methyl-cis,cis-muconate acinetobacter calcoaceticus 108000.0 108000.0 1 PMID:9726873 -5.5.1.1 3-methyl-cis,cis-muconate pseudomonas putida 35400.0 35400.0 1 PMID:9726873 -5.5.1.1 3-methyl-cis,cis-muconate pseudomonas reinekei 214.0 214.0 1 PMID:17172348 -5.5.1.1 3-methyl-cis,cis-muconate pseudomonas sp. 27.8 27.8 1 PMID:17172348 -5.5.1.1 3-methyl-cis,cis-muconate rhodococcus erythropolis 3.2 2.6 2 PMID:7751292 -5.5.1.1 3-methylmuconate pseudomonas reinekei 11.0 11.0 1 PMID:19465655 -5.5.1.1 cis,cis-muconate acinetobacter calcoaceticus 222000.0 222000.0 1 PMID:9726873 -5.5.1.1 cis,cis-muconate pseudomonas putida 756000.0 378006.95 2 PMID:6652062;PMID:9726873 -5.5.1.1 cis,cis-muconate pseudomonas reinekei 186.0 155.5 2 PMID:17172348 -5.5.1.1 cis,cis-muconate pseudomonas sp. 210.0 198.0 2 PMID:12930985;PMID:17172348 -5.5.1.1 cis,cis-muconate rhodococcus erythropolis 24.7 24.7 1 PMID:7751292 -5.5.1.1 muconolactone pseudomonas putida 1.4 1.4 1 PMID:6652062 -5.5.1.10 alpha-pinene oxide nocardia sp. 250.0 250.0 1 PMID:3667522 -5.5.1.11 2,4-dichloro-cis,cis-muconate cupriavidus necator 63.7 63.7 1 PMID:2327971 -5.5.1.11 2-chloro-cis,cis-muconate cupriavidus necator 15.8 15.8 1 PMID:2327971 -5.5.1.11 2-methyl-cis,cis-muconate cupriavidus necator 10.2 10.2 1 PMID:2327971 -5.5.1.11 3-chloro-cis,cis-muconate cupriavidus necator 119.0 119.0 1 PMID:2327971 -5.5.1.11 3-methyl-cis,cis-muconate cupriavidus necator 54.8 54.8 1 PMID:2327971 -5.5.1.11 cis,cis-muconate cupriavidus necator 51.5 51.5 1 PMID:2327971 -5.5.1.12 farnesyl diphosphate abies grandis 0.02 0.02 1 PMID:11112547 -5.5.1.12 geranylgeranyl diphosphate abies grandis 2.2 0.45 6 PMID:11112547;PMID:11552804;PMID:11827528;PMID:19201430 -5.5.1.13 (e,e,e)-geranylgeranyl diphosphate arabidopsis thaliana 0.9 0.9 1 PMID:24036329 -5.5.1.13 geranylgeranyl diphosphate cucurbita maxima 0.035 0.035 1 PMID:10644675 -5.5.1.13 geranylgeranyl diphosphate streptomyces sp. 0.033 0.033 1 PMID:17148547 -5.5.1.16 (e,e,e)-geranylgeranyl diphosphate mycobacterium tuberculosis 0.12 0.12 1 PMID:19574210 -5.5.1.2 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate agrobacterium tumefaciens 1415.0 707.96 2 PMID:17054713;PMID:17074892 -5.5.1.2 3-sulfomuconate agrobacterium tumefaciens 20.9 20.9 1 PMID:17074892 -5.5.1.20 (3e,5e,7e,10r,12e,14e,17r,18s,22s)-22-ethyl-10,18-dihydroxy-17-methyloxacyclodocosa-3,5,7,12,14-pentaene-2,16-dione saccharopolyspora spinosa 0.23 0.23 1 PMID:21544146 -5.5.1.22 geranyl diphosphate blumea balsamifera 1.49 1.49 1 PMID:34977393 -5.5.1.28 geranylgeranyl diphosphate salvia divinorum 0.88 0.88 1 PMID:28204567 -5.5.1.4 d-glucose 6-phosphate arabidopsis thaliana 0.3 0.1045 4 PMID:21729692 -5.5.1.4 d-glucose 6-phosphate archaeoglobus fulgidus 9.6 9.6 1 PMID:11015222 -5.5.1.4 d-glucose 6-phosphate corynebacterium glutamicum 0.037 0.023 2 PMID:30270521 -5.5.1.5 3-carboxy-cis,cis-muconate neurospora crassa 382.0 371.0 2 PMID:8132467 -5.5.1.5 cis,cis-muconate neurospora crassa 1.1 1.1 1 PMID:8132467 -5.5.1.6 2',4'-dihydroxy-4-methylchalcone glycine max 96.8 66.15 2 PMID:15778463 -5.5.1.6 2',4'-dihydroxychalcone glycine max 86.3 64.15 2 PMID:15778463 -5.5.1.6 2',4'-dihydroxychalcone medicago sativa 45300.0 45300.0 1 PMID:11698411 -5.5.1.6 2'-hydroxychalcone glycine max 59.9 48.65 2 PMID:15778463 -5.5.1.6 4,2',4',6'-tetrahydrochalcone medicago sativa 671000.0 670900.0 2 PMID:11698411 -5.5.1.6 4,2',4',6'-tetrahydroxychalcone citrus sinensis 1.87 1.87 1 * -5.5.1.6 4,2',4',6'-tetrahydroxychalcone glycine max 833.0 478.8 5 PMID:15778463;PMID:1772902 -5.5.1.6 4,2',4'-trihydrochalcone medicago sativa 135000.0 135000.0 1 PMID:11698411 -5.5.1.6 4,2',4'-trihydroxychalcone glycine max 183.0 107.0 5 PMID:15778463;PMID:1772902;PMID:3384815 -5.5.1.6 4,2',5'-trihydroxychalcone glycine max 62.5 47.5 2 PMID:15778463 -5.5.1.6 4,2'-dihydrochalcone medicago sativa 5530.0 5528.0 2 PMID:11698411 -5.5.1.6 4,2'-dihydroxychalcone glycine max 57.4 40.0 2 PMID:15778463 -5.5.1.6 6'-deoxychalcone marchantia paleacea 7.3 7.3 1 PMID:29083033 -5.5.1.6 6'-deoxychalcone medicago sativa 7.06 7.06 1 PMID:29083033 -5.5.1.6 6'-deoxychalcone physcomitrella appendiculatum 0.76 0.76 1 PMID:29083033 -5.5.1.6 6'-deoxychalcone selaginella moellendorffii 0.44 0.44 1 PMID:29083033 -5.5.1.6 6'-hydroxychalcone marchantia paleacea 108.7 108.7 1 PMID:29083033 -5.5.1.6 6'-hydroxychalcone medicago sativa 103.0 103.0 1 PMID:29083033 -5.5.1.6 6'-hydroxychalcone physcomitrella appendiculatum 75.6 75.6 1 PMID:29083033 -5.5.1.6 6'-hydroxychalcone selaginella moellendorffii 70.4 70.4 1 PMID:29083033 -5.5.1.6 butein eubacterium ramulus 48.33 48.33 1 PMID:15127184 -5.5.1.6 isoliquiritigenin adiantum capillus-veneris 0.4 0.4 1 PMID:31557291 -5.5.1.6 isoliquiritigenin antrophyum callifolium 0.375 0.375 1 PMID:31557291 -5.5.1.6 isoliquiritigenin deschampsia antarctica 0.02 0.02 1 PMID:29394293 -5.5.1.6 isoliquiritigenin eubacterium ramulus 38.33 38.33 1 PMID:15127184 -5.5.1.6 isoliquiritigenin oryza sativa japonica group 9.214e-05 9.214e-05 1 PMID:34685873 -5.5.1.6 naringenin chalcone adiantum capillus-veneris 156.8 156.8 1 PMID:31557291 -5.5.1.6 naringenin chalcone antrophyum callifolium 156.2 156.2 1 PMID:31557291 -5.5.1.6 naringenin chalcone deschampsia antarctica 130.3 130.3 1 PMID:29394293 -5.5.1.6 naringenin chalcone eubacterium ramulus 2300.0 1721.0 2 PMID:15127184;PMID:25849401 -5.5.1.6 naringenin chalcone lindsaea orbiculata 153.7 153.7 1 PMID:31557291 -5.5.1.6 naringenin chalcone odontosoria chusana 155.1 155.1 1 PMID:31557291 -5.5.1.6 naringenin chalcone oryza sativa japonica group 69.35 69.35 1 PMID:34685873 -5.5.1.7 (+)-2-chloromuconolactone cupriavidus necator 3.95 3.035 2 PMID:7751312 -5.5.1.7 (+)-5-chloromuconolactone cupriavidus necator 24.7 24.7 1 PMID:7751312 -5.5.1.7 2,4-dichloro-cis,cis-muconate cupriavidus necator 44.7 44.7 1 PMID:7751312 -5.5.1.7 2,4-dichloro-cis,cis-muconate rhodococcus erythropolis 22.3 22.3 1 PMID:7751292 -5.5.1.7 2-chloro-cis,cis-muconate cupriavidus necator 10.3 7.065 2 PMID:7751312 -5.5.1.7 2-chloro-cis,cis-muconate rhodococcus erythropolis 2.2 2.2 1 PMID:7751292 -5.5.1.7 2-chloro-cis,cis-muconate rhodococcus opacus 171000.0 85501.8 2 PMID:11405892;PMID:24768773 -5.5.1.7 2-methyl-cis,cis-muconate rhodococcus erythropolis 0.0567 0.0567 1 PMID:7751292 -5.5.1.7 3-chloro-cis,cis-muconate cupriavidus necator 57.7 57.7 1 PMID:7751312 -5.5.1.7 3-chloro-cis,cis-muconate rhodococcus erythropolis 60.7 60.7 1 PMID:7751292 -5.5.1.7 3-chloro-cis,cis-muconate rhodococcus opacus 8.8 8.8 1 PMID:24768773 -5.5.1.7 3-fluoro-cis,cis-muconate rhodococcus erythropolis 6.07 6.07 1 PMID:7751292 -5.5.1.7 3-methyl-cis,cis-muconate rhodococcus erythropolis 0.8 0.8 1 PMID:7751292 -5.5.1.7 3-methyl-cis,cis-muconate rhodococcus opacus 3.2 3.2 1 PMID:24768773 -5.5.1.7 cis,cis-muconate rhodococcus erythropolis 4.33 4.33 1 PMID:7751292 -5.5.1.7 cis,cis-muconate rhodococcus opacus 24.66 24.66 1 PMID:24768773 -5.5.1.8 geranyl diphosphate cinnamomum burmanni 0.01 0.01 1 PMID:33644023 -5.6.1.1 atp drosophila melanogaster 1.8 1.8 1 PMID:15823537 -5.6.1.1 atp homo sapiens 13.0 3.83 7 PMID:18491908;PMID:22637577;PMID:34121983 -5.6.1.1 atp strongylocentrotus purpuratus 0.005 0.005 1 PMID:9568719 -5.6.1.10 atp bos taurus 0.00633 0.004415 2 PMID:1356434 -5.6.1.10 atp entamoeba histolytica 0.00018 0.00018 1 PMID:24486610 -5.6.1.10 atp escherichia coli 0.167 0.0083 11 PMID:17904512;PMID:18323638;PMID:19165152;PMID:7876226;PMID:9425082 -5.6.1.10 atp homo sapiens 0.0025 0.0025 1 PMID:25615450 -5.6.1.10 atp plasmodium falciparum 0.017 0.017 1 PMID:14711509 -5.6.1.10 atp saccharomyces cerevisiae 1.2 0.013600000000000001 4 PMID:14668331;PMID:15051534;PMID:16135516;PMID:18706386 -5.6.1.10 atp schizosaccharomyces pombe 0.0438 0.03165 2 PMID:25294885 -5.6.1.10 atp sus scrofa 0.0014 0.00095 2 PMID:24535459 -5.6.1.10 atp synechococcus elongatus 0.0408 0.03305 2 PMID:25294885 -5.6.1.10 atp tetragenococcus halophilus 0.012 0.0037 3 PMID:18323638 -5.6.1.2 atp dictyostelium discoideum 121.1 63.0 2 PMID:19198589 -5.6.1.2 atp saccharomyces cerevisiae 14.1 8.92 2 PMID:18650442 -5.6.1.2 atp schizosaccharomyces pombe 2.6 2.5 2 PMID:32694211 -5.6.1.2 atp tetrahymena thermophila 5.0 2.505 2 PMID:2937451 -5.6.1.2 formycin triphosphate tetrahymena thermophila 5.0 5.0 1 * -5.6.1.3 adp neurospora crassa 34.0 34.0 1 PMID:19490122 -5.6.1.3 atp dictyostelium discoideum 144.0 60.5 3 PMID:18160177 -5.6.1.3 atp drosophila melanogaster 25.0 25.0 1 PMID:11864969 -5.6.1.3 atp homo sapiens 22.0 2.15 14 PMID:15247293;PMID:16642039;PMID:17014086;PMID:18491908;PMID:20224548;PMID:21873978;PMID:26055718 -5.6.1.3 atp mus musculus 290.9 124.7 7 PMID:17942477;PMID:23500491;PMID:35948971 -5.6.1.3 atp neurospora crassa 23.2 23.2 1 PMID:19242550 -5.6.1.3 atp plasmodium berghei 1.9 1.9 1 PMID:36384964 -5.6.1.3 atp plasmodium falciparum 1.4 1.4 1 PMID:36384964 -5.6.1.3 atp schizosaccharomyces pombe 2.4 2.4 1 PMID:19037096 -5.6.1.3 methylanthraniloyl-atp homo sapiens 0.0009 0.0009 1 PMID:21873978 -5.6.1.3 phosphate neurospora crassa 29.0 29.0 1 PMID:19490122 -5.6.1.4 atp drosophila melanogaster 3.58 1.3 9 PMID:19858211;PMID:22449971 -5.6.1.4 atp eremothecium gossypii 0.17 0.165 2 PMID:22493778 -5.6.1.4 atp saccharomyces cerevisiae 70.0 5.0 3 PMID:15385545;PMID:21680740;PMID:7912193 -5.6.1.4 atp schizosaccharomyces pombe 1.9 1.9 1 PMID:18984586 -5.6.1.5 k48-green-tail polypeptide saccharomyces cerevisiae 0.0145 0.0145 1 PMID:30675527 -5.6.1.5 k48-red polypeptide saccharomyces cerevisiae 0.0147 0.0147 1 PMID:30675527 -5.6.1.6 atp homo sapiens 14.0 7.11 2 PMID:27226582;PMID:9511931 -5.6.1.7 atp acetivibrio thermocellus 0.07 0.07 1 PMID:8687408 -5.6.1.7 atp aeropyrum pernix 2.21 2.21 1 PMID:17092293 -5.6.1.7 atp allochromatium vinosum 0.06 0.06 1 PMID:1349470 -5.6.1.7 atp bos taurus 0.133 0.026500000000000003 4 PMID:12589746;PMID:7910827 -5.6.1.7 atp cereibacter sphaeroides 0.13 0.13 1 PMID:1678280 -5.6.1.7 atp escherichia coli 0.75 0.0833 9 PMID:15474501;PMID:1678280;PMID:1974461;PMID:7727391;PMID:7819207;PMID:9256426 -5.6.1.7 atp methanococcus maripaludis 0.99 0.99 1 PMID:12628000 -5.6.1.7 atp pseudomonas phage el 9.6 9.6 1 PMID:32339190 -5.6.1.7 atp rhizobium leguminosarum 0.014 0.009 3 PMID:15474501 -5.6.1.7 atp saccharomyces cerevisiae 0.0417 0.0417 1 PMID:9256426 -5.6.1.7 atp thermoanaerobacter brockii 1.0 1.0 1 PMID:7912671 -5.6.1.7 atp thermoplasma acidophilum 0.0055 0.001915 4 PMID:10864508 -5.6.1.8 atp acanthamoeba castellanii 17.0 4.68 3 PMID:23897814;PMID:2946692 -5.6.1.8 atp caenorhabditis elegans 0.56 0.56 1 PMID:2935526 -5.6.1.8 atp dictyostelium sp. 5.7 3.0 5 PMID:10090768 -5.6.1.8 atp drosophila melanogaster 6.95 1.83 3 PMID:18462751 -5.6.1.8 atp gallus gallus 0.259 0.056999999999999995 4 PMID:19933418 -5.6.1.8 atp homo sapiens 43.1 26.4 9 PMID:12704189;PMID:31387944 -5.6.1.8 atp lethocerus griseus 4.1 1.75 4 PMID:2965161 -5.6.1.8 atp lethocerus indicus 4.1 1.75 4 PMID:2965161 -5.6.1.8 atp oryctolagus cuniculus 20.0 11.15 10 PMID:10090768;PMID:142675;PMID:2935526;PMID:6122469 -5.6.1.8 atp plasmodium falciparum 13.0 13.0 1 PMID:36273584 -5.6.2.1 negatively supercoiled plasmid pxxz06 dna escherichia coli 0.02 0.02 1 PMID:21310243 -5.6.2.2 atp bacillus subtilis 3.4 3.4 1 PMID:29032205 -5.6.2.2 atp homo sapiens 3.6 2.7 3 PMID:15647268 -5.6.2.2 atp mycobacterium tuberculosis 0.05 0.05 1 PMID:30744994 -5.6.2.2 atp saccharolobus solfataricus 2.55 2.55 1 PMID:19443439 -5.6.2.2 atp saccharomyces cerevisiae 7.2 2.35 4 PMID:15647268;PMID:16782968 -5.6.2.2 dna homo sapiens 3.38 3.38 1 PMID:16053917 -5.6.2.3 atp homo sapiens 43.3 2.04 4 PMID:20659899;PMID:22582397 -5.6.2.3 atp severe acute respiratory syndrome-related coronavirus 19.1 19.1 1 PMID:12917423 -5.6.2.3 ctp severe acute respiratory syndrome-related coronavirus 13.9 13.9 1 PMID:12917423 -5.6.2.3 datp severe acute respiratory syndrome-related coronavirus 14.8 14.8 1 PMID:12917423 -5.6.2.3 dctp severe acute respiratory syndrome-related coronavirus 14.3 14.3 1 PMID:12917423 -5.6.2.3 dgtp severe acute respiratory syndrome-related coronavirus 7.5 7.5 1 PMID:12917423 -5.6.2.3 dutp severe acute respiratory syndrome-related coronavirus 14.8 14.8 1 PMID:12917423 -5.6.2.3 gtp severe acute respiratory syndrome-related coronavirus 5.4 5.4 1 PMID:12917423 -5.6.2.3 utp severe acute respiratory syndrome-related coronavirus 10.5 10.5 1 PMID:12917423 -5.6.2.4 2'(3')-o-(n-methylanthraniloyl)atp geobacillus stearothermophilus 17.2 8.65 2 PMID:19647000 -5.6.2.4 atp drosophila melanogaster 15.0 7.5215 2 PMID:11452023 -5.6.2.4 atp escherichia coli 2.17 2.17 1 PMID:27484483 -5.6.2.4 atp geobacillus stearothermophilus 16.9 8.6 2 PMID:19647000 -5.6.2.4 atp hepacivirus hominis 5.82 5.82 1 PMID:11903057 -5.6.2.4 atp homo sapiens 11.25 6.375 2 PMID:19151156 -5.6.2.4 atp mycobacterium tuberculosis 29.8 21.0 4 PMID:17158674 -5.6.2.4 atp saccharolobus solfataricus 0.068 0.067 3 PMID:19073923;PMID:20716382 -5.6.2.4 atp saccharomyces cerevisiae 9.2 8.8 3 PMID:11376001;PMID:16358299 -5.6.2.4 datp drosophila melanogaster 23.0 11.625 2 PMID:11452023 -5.6.2.5 atp homo sapiens 0.057 0.057 1 PMID:11903057 -5.6.2.6 atp hepacivirus hominis 5.82 5.82 1 PMID:11903057 -5.6.2.6 atp homo sapiens 0.057 0.057 1 PMID:11903057 -5.6.2.6 atp leishmania major 1.37 1.37 1 PMID:21321231 -5.6.2.6 atp saccharomyces cerevisiae 22.2 22.2 1 PMID:18096702 -5.6.2.6 atp west nile virus 3.0 3.0 1 PMID:20421212 -5.6.2.6 gtp west nile virus 2.75 2.75 1 PMID:20421212 -5.6.2.7 atp escherichia coli 1.28 1.0 2 PMID:27813083 -5.6.2.7 atp saccharomyces cerevisiae 3.5 3.5 1 PMID:15201868 -5.6.2.7 rna bacillus subtilis 1.48 1.23 2 PMID:18184816 -5.99.1.4 (3e)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate pseudomonas putida 19.0 19.0 1 PMID:17508726 -5.99.1.4 2-hydroxy-2h-chromene-2-carboxylate pseudomonas putida 47.0 47.0 1 PMID:17508726 -6.1.1.1 3-chloro-l-tyrosine saccharomyces cerevisiae 0.13 0.13 1 PMID:11530018 -6.1.1.1 3-fluoro-d,l-tyrosine saccharomyces cerevisiae 4.96 4.13 2 PMID:11530018 -6.1.1.1 a22g mutated trnatyr transcript homo sapiens 3e-05 3e-05 1 PMID:18268021 -6.1.1.1 atp acidithiobacillus ferrooxidans 7.7 5.29 3 PMID:11240138 -6.1.1.1 atp escherichia coli 14.2 14.2 1 PMID:28741290 -6.1.1.1 atp geobacillus stearothermophilus 7.7 7.7 1 PMID:9660761 -6.1.1.1 atp pseudomonas aeruginosa 3.8 3.45 2 PMID:32583746 -6.1.1.1 d-tyrosine saccharomyces cerevisiae 1.2 1.2 1 PMID:11530018 -6.1.1.1 g15a mutated trnatyr transcript homo sapiens 0.0002 0.0002 1 PMID:18268021 -6.1.1.1 l-3,4-dihydroxyphenylalanine saccharomyces cerevisiae 1.65 1.65 1 PMID:11530018 -6.1.1.1 l-beta-(5-hydroxy-2-pyridyl)-alanine escherichia coli 0.11 0.11 1 PMID:11006270 -6.1.1.1 l-tyrosine acidithiobacillus ferrooxidans 7.7 5.29 3 PMID:11240138 -6.1.1.1 l-tyrosine cricetulus griseus 12.5 12.5 1 PMID:24828507 -6.1.1.1 l-tyrosine escherichia coli 14.2 9.04 4 PMID:11006270;PMID:12097643;PMID:28741290 -6.1.1.1 l-tyrosine geobacillus stearothermophilus 5.4 5.4 1 PMID:9660761 -6.1.1.1 l-tyrosine homo sapiens 45.0 6.08 3 PMID:12016229;PMID:12509991 -6.1.1.1 l-tyrosine methanocaldococcus jannaschii 0.53 0.53 1 PMID:19386777 -6.1.1.1 l-tyrosine pseudomonas aeruginosa 3.8 2.4 2 PMID:32583746 -6.1.1.1 l-tyrosine saccharomyces cerevisiae 4.6 4.5 2 PMID:11530018 -6.1.1.1 native yeast trnatyr saccharomyces cerevisiae 1.5 1.5 1 PMID:10677221 -6.1.1.1 trnacua saccharomyces cerevisiae 0.197 0.197 1 * -6.1.1.1 trnatyr aeropyrum pernix 0.29 0.29 2 PMID:23024156 -6.1.1.1 trnatyr escherichia coli 1.32 1.32 1 PMID:28741290 -6.1.1.1 trnatyr homo sapiens 0.046 0.046 1 PMID:18268021 -6.1.1.1 trnatyr plasmodium falciparum 0.016 0.016 1 PMID:30592748 -6.1.1.1 trnatyr pseudomonas aeruginosa 1.9 1.05 2 PMID:32583746 -6.1.1.1 trnatyr saccharomyces cerevisiae 6.08 6.08 1 PMID:4578388 -6.1.1.1 trnatyr(g34c) methanocaldococcus jannaschii 0.07 0.07 1 PMID:12754495 -6.1.1.1 trnatyr(wild-type) methanocaldococcus jannaschii 0.19 0.19 1 PMID:12754495 -6.1.1.1 u54c mutated trnatyr transcript homo sapiens 0.012 0.012 1 PMID:18268021 -6.1.1.10 (s)-2-aminohex-5-enoic acid escherichia coli 1.35 1.35 1 * -6.1.1.10 (s)-2-aminohex-5-ynoic acid escherichia coli 2.6 2.6 1 * -6.1.1.10 atp escherichia coli 5.6 5.6 1 * -6.1.1.10 atp homo sapiens 0.033 0.033 1 PMID:15274629 -6.1.1.10 atp xanthomonas citri 0.33 0.33 1 PMID:33857480 -6.1.1.10 coa saccharomyces cerevisiae 1.6 1.15 2 PMID:11469869 -6.1.1.10 l-homocysteine saccharomyces cerevisiae 6.08 0.69 3 PMID:11469869 -6.1.1.10 l-met mycolicibacterium smegmatis 3.13 3.035 2 PMID:971320 -6.1.1.10 l-methionine clostridioides difficile 23.0 23.0 1 PMID:19258353 -6.1.1.10 l-methionine escherichia coli 13.3 9.45 2 * -6.1.1.10 l-methionine homo sapiens 1.85 1.1300000000000001 2 PMID:15274629;PMID:29775242 -6.1.1.10 l-methionine staphylococcus aureus 25.0 25.0 1 PMID:19015366 -6.1.1.10 l-methionine xanthomonas citri 0.207 0.207 1 PMID:33857480 -6.1.1.10 l-methionyl-trnamet escherichia coli 0.157 0.157 1 PMID:25097229 -6.1.1.10 l-norleucine escherichia coli 2.15 2.15 1 * -6.1.1.10 l-trans-alpha-crotylglycine escherichia coli 2.94 2.38 2 * -6.1.1.10 met-trnamet saccharomyces cerevisiae 6.0 6.0 1 PMID:3905796 -6.1.1.10 trna fraction from saccharomyces cerevisiae oryza sativa 6.08 3.305 2 PMID:11118226 -6.1.1.10 trnamet clostridioides difficile 0.08 0.08 1 PMID:19258353 -6.1.1.10 trnamet escherichia coli 42.0 3.3 5 PMID:12390027;PMID:21175197;PMID:2126467;PMID:9607323 -6.1.1.10 trnamet homo sapiens 11.0 0.15 7 PMID:11714285;PMID:15274629 -6.1.1.10 trnamet mycobacterium tuberculosis 6.0 4.415 2 PMID:9607323 -6.1.1.10 trnamet oryza sativa 0.29 0.29 1 PMID:11118226 -6.1.1.10 trnamet saccharomyces cerevisiae 1.3 1.0 3 PMID:11469869 -6.1.1.10 trnamet staphylococcus aureus 0.49 0.49 1 PMID:19015366 -6.1.1.11 atp saccharomyces cerevisiae 3.9 0.99 5 PMID:11004561;PMID:12392560;PMID:8576207;PMID:8995413 -6.1.1.11 dl-serine hydroxamate zea mays 2.433 2.433 1 PMID:23228595 -6.1.1.11 l-cysteine zea mays 0.078 0.078 1 PMID:23228595 -6.1.1.11 l-ser methanosarcina barkeri 2.06 2.06 1 PMID:18422966 -6.1.1.11 l-ser saccharomyces cerevisiae 0.46 0.46 1 PMID:18067851 -6.1.1.11 l-ser zea mays 2.8 2.8 1 PMID:18067851 -6.1.1.11 l-serine methanosarcina barkeri 1.7 1.38 2 PMID:16675947;PMID:21704670 -6.1.1.11 l-serine saccharomyces cerevisiae 0.22 0.22 1 PMID:11004561 -6.1.1.11 l-serine streptomyces sp. 7.0 4.4 2 PMID:19721072 -6.1.1.11 l-serine zea mays 6.9 2.5 3 PMID:11747308;PMID:23228595 -6.1.1.11 l-seryl-trnaser saccharomyces cerevisiae 0.833 0.833 1 * -6.1.1.11 l-threonine zea mays 0.14 0.14 1 PMID:23228595 -6.1.1.11 ser saccharomyces cerevisiae 3.8 0.97 3 PMID:8576207;PMID:8995413 -6.1.1.11 trnasec homo sapiens 9.2 4.6034999999999995 2 PMID:28808125;PMID:9637248 -6.1.1.11 trnasec mutant without anticodon arm homo sapiens 0.005 0.005 1 PMID:9637248 -6.1.1.11 trnasecux escherichia coli 0.0023 0.0023 1 PMID:30317559 -6.1.1.11 trnaser arabidopsis thaliana 0.28 0.17500000000000002 2 PMID:30570212 -6.1.1.11 trnaser homo sapiens 13.7 0.43 3 PMID:24095058;PMID:28808125;PMID:9637248 -6.1.1.11 trnaser methanosarcina barkeri 0.473 0.454 3 PMID:18422966;PMID:19228694 -6.1.1.11 trnaser methanothermobacter thermautotrophicus 0.1 0.05365 2 PMID:21098026 -6.1.1.11 trnaser saccharomyces cerevisiae 1.1 0.55 5 PMID:11004561;PMID:18067851;PMID:8576207;PMID:8995413 -6.1.1.11 trnaser streptomyces sp. 1.37 0.125 3 PMID:19721072 -6.1.1.11 trnaser zea mays 1.48 1.0 6 PMID:11747308;PMID:18067851;PMID:23228595 -6.1.1.11 trnaser (escherichia coli) arabidopsis thaliana 0.14 0.14 1 * -6.1.1.11 trnaser (saccharomyces cerevisiae) arabidopsis thaliana 0.13 0.13 1 * -6.1.1.11 trnaser mutant without anticodon arm homo sapiens 0.023 0.023 1 PMID:9637248 -6.1.1.11 trnaser(cga) methanosarcina barkeri 3.05 2.06 2 PMID:15364939 -6.1.1.11 trnaser(gcu) methanosarcina barkeri 1.13 1.025 2 PMID:15364939 -6.1.1.11 trnaser(gga) methanosarcina barkeri 4.4 2.6500000000000004 2 PMID:15364939 -6.1.1.11 trnasergcu bos taurus 6.08 0.495 4 PMID:10764807;PMID:11577083 -6.1.1.11 trnaseruga bos taurus 6.08 3.375 6 PMID:10764807;PMID:11577083 -6.1.1.11 trnautu1 escherichia coli 0.082 0.082 1 PMID:30317559 -6.1.1.11 trnautux escherichia coli 0.0013 0.0013 1 PMID:30317559 -6.1.1.12 asp escherichia coli 18.0 18.0 1 PMID:9171418 -6.1.1.12 aspartyl-trna saccharomyces cerevisiae 16.9 16.9 1 PMID:4570972 -6.1.1.12 atp homo sapiens 6.7 6.7 1 PMID:19443655 -6.1.1.12 atp leishmania donovani 0.066 0.066 1 PMID:33736288 -6.1.1.12 atp plasmodium falciparum 5.9 5.9 1 PMID:19443655 -6.1.1.12 atp pseudomonas aeruginosa 24.0 24.0 1 PMID:29186665 -6.1.1.12 l-aspartate leishmania donovani 0.28 0.28 1 PMID:33736288 -6.1.1.12 l-aspartate pseudomonas aeruginosa 10.0 10.0 1 PMID:29186665 -6.1.1.12 trnaasn thermus thermophilus 0.12 0.092 3 PMID:10727213;PMID:12660169 -6.1.1.12 trnaasp escherichia coli 12.0 0.55 3 PMID:12766171;PMID:15289581;PMID:23275545 -6.1.1.12 trnaasp homo sapiens 0.22 0.0635 6 PMID:15779907;PMID:17384640;PMID:19443655;PMID:23275545 -6.1.1.12 trnaasp plasmodium falciparum 0.2 0.2 1 PMID:19443655 -6.1.1.12 trnaasp pseudomonas aeruginosa 0.21 0.21 1 PMID:29186665 -6.1.1.12 trnaasp saccharomyces cerevisiae 9.3 9.3 1 PMID:10452887 -6.1.1.12 trnaasp thermococcus kodakarensis 0.061 0.061 3 PMID:12660169;PMID:12730374 -6.1.1.12 trnaasp thermus thermophilus 2.7 0.24 3 PMID:10727213;PMID:12660169 -6.1.1.12 trnaaspa73 escherichia coli 0.0029 0.0029 1 PMID:12766171 -6.1.1.14 trna1gly bombyx mori 15.9 15.9 1 PMID:4044548 -6.1.1.14 trna2gly bombyx mori 8.1 8.1 1 PMID:4044548 -6.1.1.14 trnagly saccharomyces cerevisiae 0.73 0.33 3 PMID:23816885 -6.1.1.15 atp escherichia coli 81.0 81.0 1 PMID:9062123 -6.1.1.15 atp pseudomonas aeruginosa 5.5 5.5 1 PMID:30666738 -6.1.1.15 cis-4-hydroxyproline escherichia coli 21.0 21.0 1 PMID:16864571 -6.1.1.15 l-alanine escherichia coli 3.52 1.7 3 PMID:11408489;PMID:16864571;PMID:22356126 -6.1.1.15 l-alanine homo sapiens 0.11 0.11 1 PMID:11408489 -6.1.1.15 l-cysteine acetoanaerobium sticklandii 0.39 0.39 1 PMID:12130657 -6.1.1.15 l-cysteine aquifex aeolicus 0.09 0.09 1 PMID:12130657 -6.1.1.15 l-cysteine borreliella burgdorferi 0.12 0.12 1 PMID:12130657 -6.1.1.15 l-cysteine cytophaga hutchinsonii 0.083 0.083 1 PMID:12130657 -6.1.1.15 l-cysteine deinococcus radiodurans 0.014 0.014 1 PMID:12130657 -6.1.1.15 l-cysteine escherichia coli 0.022 0.022 1 PMID:12130657 -6.1.1.15 l-cysteine methanocaldococcus jannaschii 0.19 0.105 2 PMID:11141055;PMID:12130657 -6.1.1.15 l-cysteine methanococcus maripaludis 0.8 0.8 1 PMID:11717392 -6.1.1.15 l-cysteine methanothermobacter thermautotrophicus 0.02 0.02 1 PMID:12130657 -6.1.1.15 l-cysteine novosphingobium aromaticivorans 0.065 0.065 1 PMID:12130657 -6.1.1.15 l-cysteine paramagnetospirillum magnetotacticum 0.11 0.11 1 PMID:12130657 -6.1.1.15 l-cysteine rhodopseudomonas palustris 0.025 0.025 1 PMID:12130657 -6.1.1.15 l-cysteine saccharomyces cerevisiae 0.003 0.003 1 PMID:12130657 -6.1.1.15 l-cysteine thermus thermophilus 0.04 0.04 1 PMID:12130657 -6.1.1.15 l-proline acetoanaerobium sticklandii 60.0 60.0 1 PMID:12130657 -6.1.1.15 l-proline aquifex aeolicus 15.0 15.0 1 PMID:12130657 -6.1.1.15 l-proline arabidopsis thaliana 57.5 35.35 2 PMID:27332880 -6.1.1.15 l-proline borreliella burgdorferi 34.0 34.0 1 PMID:12130657 -6.1.1.15 l-proline cytophaga hutchinsonii 19.0 19.0 1 PMID:12130657 -6.1.1.15 l-proline deinococcus radiodurans 32.0 32.0 1 PMID:12130657 -6.1.1.15 l-proline escherichia coli 70.0 13.35 6 PMID:11408489;PMID:12130657;PMID:16864571;PMID:22356126;PMID:23731272;PMID:24450765 -6.1.1.15 l-proline homo sapiens 80.0 80.0 1 PMID:11408489 -6.1.1.15 l-proline methanocaldococcus jannaschii 210.0 63.0 3 PMID:11141055;PMID:11408489;PMID:12130657 -6.1.1.15 l-proline methanococcus maripaludis 0.9 0.9 1 PMID:11717392 -6.1.1.15 l-proline methanothermobacter thermautotrophicus 3.4 3.4 1 PMID:12130657 -6.1.1.15 l-proline novosphingobium aromaticivorans 26.0 26.0 1 PMID:12130657 -6.1.1.15 l-proline paramagnetospirillum magnetotacticum 35.0 35.0 1 PMID:12130657 -6.1.1.15 l-proline pseudomonas aeruginosa 6.3 6.3 1 PMID:30666738 -6.1.1.15 l-proline rhodopseudomonas palustris 14.0 14.0 1 PMID:12130657 -6.1.1.15 l-proline saccharomyces cerevisiae 5.6 5.6 1 PMID:12130657 -6.1.1.15 l-proline thermus thermophilus 35.0 35.0 1 PMID:12130657 -6.1.1.15 trans-4-hydroxyproline escherichia coli 15.0 15.0 1 PMID:16864571 -6.1.1.15 trnapro deinococcus radiodurans 10.8 9.8 3 PMID:16843487 -6.1.1.15 trnapro escherichia coli 0.239 0.239 1 PMID:16864571 -6.1.1.15 trnapro methanocaldococcus jannaschii 1.6 1.09 2 PMID:11827467;PMID:16226256 -6.1.1.15 trnapro methanothermobacter thermautotrophicus 6.9 4.0 4 PMID:15917221 -6.1.1.15 trnapro pseudomonas aeruginosa 0.2 0.2 1 PMID:30666738 -6.1.1.16 atp escherichia coli 142.0 57.0 5 PMID:12662918;PMID:14679218;PMID:15882062 -6.1.1.16 l-cysteine escherichia coli 140.0 35.0 7 PMID:12662918;PMID:14679218;PMID:16843487;PMID:21890630;PMID:31296657 -6.1.1.16 l-cysteine homo sapiens 10.3 10.3 1 PMID:17303165 -6.1.1.16 l-cysteine methanococcus maripaludis 2.2 2.2 1 PMID:11717392 -6.1.1.16 l-cysteinyl-trnacys escherichia coli 0.017 0.017 1 PMID:8165127 -6.1.1.16 selenocysteine escherichia coli 50.3 50.3 1 PMID:31296657 -6.1.1.16 trna1cys methanosarcina mazei 0.17 0.17 1 PMID:18559341 -6.1.1.16 trna1cysa33u methanosarcina mazei 0.16 0.16 1 PMID:18559341 -6.1.1.16 trna2cys methanosarcina mazei 0.06 0.06 1 PMID:18559341 -6.1.1.16 trna3cys methanosarcina mazei 0.03 0.03 1 PMID:18559341 -6.1.1.16 trna3cysc20u/u21c/a44u/c46a/a47g methanosarcina mazei 0.14 0.14 1 PMID:18559341 -6.1.1.16 trna3cysc20u/u21c/a44u/c46a/a47g/g57a methanosarcina mazei 0.18 0.18 1 PMID:18559341 -6.1.1.16 trna3cysg57a methanosarcina mazei 0.09 0.09 1 PMID:18559341 -6.1.1.16 trna3cysu33a methanosarcina mazei 0.05 0.05 1 PMID:18559341 -6.1.1.16 trnacys escherichia coli 6.0 2.5 9 PMID:10860750;PMID:12662918;PMID:14679218;PMID:15489861;PMID:15882062;PMID:16843487 -6.1.1.16 trnacys halobacterium sp. 0.11 0.11 1 PMID:16734420 -6.1.1.16 trnacys homo sapiens 2.3 2.3 1 PMID:17303165 -6.1.1.17 atp escherichia coli 2.2 2.2 1 PMID:15096594 -6.1.1.17 atp mycobacterium tuberculosis 0.272 0.272 1 PMID:19187240 -6.1.1.17 atp plasmodium falciparum 1.18 1.18 1 PMID:24072705 -6.1.1.17 glu escherichia coli 2.2 2.2 1 PMID:15096594 -6.1.1.17 glutrna escherichia coli 0.8 0.8 1 PMID:3003503 -6.1.1.17 l-glutamate mycobacterium tuberculosis 2.15 2.15 1 PMID:19187240 -6.1.1.17 l-glutamate plasmodium falciparum 1.39 1.39 1 PMID:24072705 -6.1.1.17 l-glutamate saccharomyces cerevisiae 1.5 1.5 1 PMID:25149203 -6.1.1.17 trnagln homo sapiens 0.95 0.95 1 PMID:19805282 -6.1.1.17 trnagln plasmodium falciparum 2.11 1.265 2 PMID:24072705 -6.1.1.17 trnagln(cug) methanothermobacter thermautotrophicus 0.041 0.041 1 PMID:22158897 -6.1.1.17 trnagln(uug) methanothermobacter thermautotrophicus 0.006 0.006 1 PMID:22158897 -6.1.1.17 trnaglu escherichia coli 3.4 3.0 3 PMID:10215844;PMID:368055;PMID:4560497 -6.1.1.17 trnaglu homo sapiens 0.31 0.31 1 PMID:19805282 -6.1.1.17 trnaglu methanothermobacter thermautotrophicus 0.04 0.04 1 PMID:22158897 -6.1.1.17 trnaglu mycobacterium tuberculosis 0.408 0.408 1 PMID:19187240 -6.1.1.17 trnaglu plasmodium falciparum 3.61 2.02 2 PMID:24072705 -6.1.1.17 trnaglu pseudomonas aeruginosa 0.8 0.8 1 PMID:26116192 -6.1.1.17 trnaglu saccharomyces cerevisiae 1.5 0.758 2 PMID:15667228;PMID:25149203 -6.1.1.17 trnaglu mutant c36g thermus thermophilus 0.18 0.18 1 PMID:11224561 -6.1.1.17 wild type trnaglu thermus thermophilus 2.1 2.1 1 PMID:11224561 -6.1.1.18 atp escherichia coli 2.8 2.8 1 PMID:9657697 -6.1.1.18 l-glutamate escherichia coli 0.046 0.046 1 PMID:18477696 -6.1.1.18 l-glutamine escherichia coli 6.0 2.91 4 PMID:15845536;PMID:18477696;PMID:9657697 -6.1.1.18 l-glutamine saccharomyces cerevisiae 1.4 1.4 1 PMID:25149203 -6.1.1.18 trnagln escherichia coli 3.3 3.3 1 PMID:6989402 -6.1.1.18 trnagln homo sapiens 0.203 0.203 1 PMID:26869582 -6.1.1.18 trnagln pseudomonas aeruginosa 0.15 0.15 2 PMID:31833153 -6.1.1.18 trnagln saccharomyces cerevisiae 1.4 1.4 1 PMID:25149203 -6.1.1.19 arg saccharomyces cerevisiae 3.22 1.925 2 PMID:2691248 -6.1.1.19 atp escherichia coli 26.0 26.0 1 PMID:9748544 -6.1.1.19 atp homo sapiens 15.5 3.4 3 PMID:16055448;PMID:20923763 -6.1.1.19 l-arginine canavalia ensiformis 0.337 0.276 2 PMID:18562210 -6.1.1.19 l-arginine homo sapiens 17.9 3.8 3 PMID:16055448;PMID:20923763 -6.1.1.19 trnaarg cricetulus sp. 1.8 0.0045 3 PMID:15078106;PMID:16342945 -6.1.1.19 trnaarg escherichia coli 26.0 19.45 4 PMID:11733016;PMID:14672708 -6.1.1.19 trnaarg homo sapiens 16.5 1.43 4 PMID:16055448;PMID:16430231;PMID:20923763 -6.1.1.19 trnaarg methanothermobacter thermautotrophicus 0.034 0.03 2 PMID:21098026 -6.1.1.19 trnaarg(acg) canavalia ensiformis 0.105 0.08 2 PMID:22831759 -6.1.1.19 trnaarg(acg) escherichia coli 0.02 0.01085 2 PMID:22831759 -6.1.1.19 trnaarg(acg) glycine max 0.04 0.035 2 PMID:22831759 -6.1.1.2 ammonia escherichia coli 5.7 5.7 1 PMID:3881255 -6.1.1.2 archeoglobus fulgidus trnatrp(a73, wild-type) archaeoglobus fulgidus 0.53 0.53 1 PMID:11834741 -6.1.1.2 archeoglobus fulgidus trnatrp(a73c) archaeoglobus fulgidus 0.11 0.11 1 PMID:11834741 -6.1.1.2 archeoglobus fulgidus trnatrp(a73g) archaeoglobus fulgidus 0.07 0.07 1 PMID:11834741 -6.1.1.2 archeoglobus fulgidus trnatrp(a73u) archaeoglobus fulgidus 0.09 0.09 1 PMID:11834741 -6.1.1.2 atp bacillus subtilis 22.0 22.0 1 PMID:15280378 -6.1.1.2 atp homo sapiens 1.4 1.25 2 PMID:10828066;PMID:11676605 -6.1.1.2 bacillus subtilis trnatrp(a73, wild-type) archaeoglobus fulgidus 0.14 0.14 1 PMID:11834741 -6.1.1.2 bacillus subtilis trnatrp(a73c) archaeoglobus fulgidus 0.06 0.06 1 PMID:11834741 -6.1.1.2 bacillus subtilis trnatrp(a73g) archaeoglobus fulgidus 0.04 0.04 1 PMID:11834741 -6.1.1.2 bacillus subtilis trnatrp(a73u) archaeoglobus fulgidus 0.05 0.05 1 PMID:11834741 -6.1.1.2 bovine trnatrp(g73, wild-type) archaeoglobus fulgidus 0.03 0.03 1 PMID:11834741 -6.1.1.2 bovine trnatrp(g73a) archaeoglobus fulgidus 0.08 0.08 1 PMID:11834741 -6.1.1.2 bovine trnatrp(g73c) archaeoglobus fulgidus 0.06 0.06 1 PMID:11834741 -6.1.1.2 bovine trnatrp(g73u) archaeoglobus fulgidus 0.04 0.04 1 PMID:11834741 -6.1.1.2 l-tryptophan acidithiobacillus ferrooxidans 24.5 24.5 1 PMID:12482597 -6.1.1.2 l-tryptophan bacillus subtilis 0.9 0.9 1 PMID:11966471 -6.1.1.2 l-tryptophan geobacillus stearothermophilus 5.45 5.165 2 PMID:24394410 -6.1.1.2 l-tryptophan homo sapiens 1.2 1.15 2 PMID:10828066;PMID:11676605 -6.1.1.2 trnaarg aeropyrum pernix k1 0.16 0.16 1 PMID:19179361 -6.1.1.2 trnatrp acidithiobacillus ferrooxidans 6.0 4.585 2 PMID:12482597 -6.1.1.2 trnatrp aeropyrum pernix k1 16.0 16.0 1 PMID:19179361 -6.1.1.2 trnatrp bacillus subtilis 0.9 0.61 2 PMID:11966471;PMID:15280378 -6.1.1.2 trnatrp homo sapiens 1.37 1.33 3 PMID:11676605;PMID:16798914;PMID:17726052 -6.1.1.2 trp bacillus subtilis 22.0 22.0 1 PMID:15280378 -6.1.1.20 2-l-tyrosine saccharomyces cerevisiae 39.4 39.4 1 PMID:27226603 -6.1.1.20 3,4-dihydroxy-l-phenylalanine homo sapiens 0.23 0.14350000000000002 2 PMID:22035791 -6.1.1.20 3,4-dihydroxy-l-phenylalanine thermus thermophilus 0.16 0.16 1 PMID:22035791 -6.1.1.20 3-l-tyrosine saccharomyces cerevisiae 26.0 26.0 1 PMID:27226603 -6.1.1.20 atp homo sapiens 2.9 2.9 1 PMID:10329163 -6.1.1.20 atp pseudomonas aeruginosa 13.2 13.2 1 PMID:25601215 -6.1.1.20 atp streptococcus pneumoniae 15.5 15.5 1 PMID:25601215 -6.1.1.20 benzofuranylalanine escherichia coli 2.3 2.3 1 PMID:15004015 -6.1.1.20 dl-m-tyrosine homo sapiens 0.65 0.35100000000000003 2 PMID:22035791 -6.1.1.20 l-phe escherichia coli 1.72 1.72 1 PMID:15526031 -6.1.1.20 l-phe saccharomyces cerevisiae 240.0 195.0 2 PMID:16162501 -6.1.1.20 l-phenylalanine escherichia coli 199.0 101.17 2 PMID:16866361;PMID:20160120 -6.1.1.20 l-phenylalanine homo sapiens 1.1 0.1325 6 PMID:10329163;PMID:22035791;PMID:26645192;PMID:28419689 -6.1.1.20 l-phenylalanine pseudomonas aeruginosa 16.2 16.2 1 PMID:25601215 -6.1.1.20 l-phenylalanine saccharolobus solfataricus 0.115 0.085 2 PMID:12007606 -6.1.1.20 l-phenylalanine saccharomyces cerevisiae 603.0 180.0 3 PMID:20160120;PMID:27226603 -6.1.1.20 l-phenylalanine streptococcus pneumoniae 22.5 22.5 1 PMID:25601215 -6.1.1.20 l-phenylalanine thermus thermophilus 1.12 1.12 1 PMID:22035791 -6.1.1.20 l-tyr saccharomyces cerevisiae 160.0 160.0 1 PMID:16162501 -6.1.1.20 l-tyrosine escherichia coli 35.0 35.0 1 PMID:20160120 -6.1.1.20 l-tyrosine homo sapiens 0.033 0.033 1 PMID:22035791 -6.1.1.20 l-tyrosine saccharomyces cerevisiae 184.0 94.5 2 PMID:20160120 -6.1.1.20 trnaphe escherichia coli 0.82 0.44849999999999995 2 PMID:16866361 -6.1.1.20 trnaphe homo sapiens 0.19 0.15 2 PMID:10329163;PMID:28419689 -6.1.1.20 trnaphe pseudomonas aeruginosa 0.74 0.74 1 PMID:25601215 -6.1.1.20 trnaphe streptococcus pneumoniae 0.93 0.93 1 PMID:25601215 -6.1.1.21 atp escherichia coli 130.0 77.0 4 PMID:16741232;PMID:9131996;PMID:9266856 -6.1.1.21 atp homo sapiens 5.8 5.8 1 PMID:29235198 -6.1.1.21 atp pseudomonas aeruginosa 16.8 16.8 1 PMID:28745975 -6.1.1.21 atp saccharomyces cerevisiae 40.0 40.0 1 PMID:16741232 -6.1.1.21 his escherichia coli 142.0 6.5 4 PMID:9131996;PMID:9266856 -6.1.1.21 l-histidine escherichia coli 130.0 130.0 1 PMID:16741232 -6.1.1.21 l-histidine homo sapiens 4.1 4.1 1 PMID:29235198 -6.1.1.21 l-histidine pseudomonas aeruginosa 8.32 8.32 1 PMID:28745975 -6.1.1.21 l-histidine saccharomyces cerevisiae 40.0 40.0 1 PMID:16741232 -6.1.1.21 rna microhelix escherichia coli 0.024 0.024 1 PMID:16741232 -6.1.1.21 rna microhelix saccharomyces cerevisiae 0.0013 0.0013 1 PMID:16741232 -6.1.1.21 synthetic trnahis a-1 escherichia coli 0.018 0.018 1 PMID:14744140 -6.1.1.21 synthetic trnahis g-1 escherichia coli 4.75 4.75 1 PMID:14744140 -6.1.1.21 trnahis caulobacter vibrioides 4.0 4.0 1 PMID:21087993 -6.1.1.21 trnahis escherichia coli 2.02 1.865 2 PMID:15751955;PMID:16741232 -6.1.1.21 trnahis homo sapiens 5.4 5.4 1 PMID:29235198 -6.1.1.21 trnahis pseudomonas aeruginosa 0.57 0.57 1 PMID:28745975 -6.1.1.21 trnahis saccharomyces cerevisiae 0.42 0.4185 2 PMID:16741232;PMID:21321019 -6.1.1.21 trnahiscua escherichia coli 1.5 0.88 2 PMID:9131996 -6.1.1.21 u73trnahisgug escherichia coli 0.016 0.0105 2 PMID:9131996 -6.1.1.21 wild type trnahis escherichia coli 2.6 1.62 2 PMID:9131996 -6.1.1.21 wild-type full length trnahis g-1 escherichia coli 2.94 2.49 2 PMID:14744140 -6.1.1.22 asn escherichia coli 2.8 2.8 5 PMID:1544480;PMID:2009959 -6.1.1.22 atp escherichia coli 2.2 1.3 3 PMID:1544480;PMID:2009959 -6.1.1.22 atp plasmodium falciparum 10.1 10.1 1 PMID:24196969 -6.1.1.22 l-asparagine plasmodium falciparum 4.2 4.2 1 PMID:24196969 -6.1.1.22 trnaasn plasmodium falciparum 0.5 0.5 1 PMID:24196969 -6.1.1.22 trnaasn staphylococcus aureus 0.043 0.043 1 PMID:24685427 -6.1.1.23 trnaasn bacillus subtilis 0.058 0.058 1 PMID:26804570 -6.1.1.23 trnaasn bdellovibrio bacteriovorus 0.17 0.17 1 PMID:25338061 -6.1.1.23 trnaasn deinococcus radiodurans 0.51 0.51 1 PMID:15781458 -6.1.1.23 trnaasn halalkalibacterium halodurans 0.012 0.012 1 PMID:26804570 -6.1.1.23 trnaasn helicobacter pylori 0.014 0.014 1 PMID:16800632 -6.1.1.23 trnaasn pseudomonas aeruginosa 0.111 0.111 1 PMID:25548166 -6.1.1.23 trnaasn staphylococcus aureus 0.2 0.2 1 PMID:24685427 -6.1.1.23 trnaasn thermus thermophilus 0.092 0.092 1 PMID:10727213 -6.1.1.23 trnaasp bacillus subtilis 0.36 0.36 1 PMID:26804570 -6.1.1.23 trnaasp bdellovibrio bacteriovorus 0.52 0.52 1 PMID:25338061 -6.1.1.23 trnaasp deinococcus radiodurans 0.15 0.15 1 PMID:15781458 -6.1.1.23 trnaasp halalkalibacterium halodurans 0.115 0.115 1 PMID:26804570 -6.1.1.23 trnaasp helicobacter pylori 0.022 0.022 1 PMID:16800632 -6.1.1.23 trnaasp staphylococcus aureus 0.24 0.24 1 PMID:24685427 -6.1.1.23 trnaasp thermus thermophilus 7.2 3.72 2 PMID:10727213 -6.1.1.24 atp escherichia coli 0.1 0.1 1 PMID:20617848 -6.1.1.24 atp methanothermobacter thermautotrophicus 0.1 0.1 1 PMID:20617848 -6.1.1.24 l-glu escherichia coli 0.09 0.09 1 PMID:20617848 -6.1.1.24 l-glu methanothermobacter thermautotrophicus 0.09 0.09 1 PMID:20617848 -6.1.1.24 trnagln bacillus subtilis 0.07 0.05500000000000001 2 PMID:3079749 -6.1.1.24 trnagln escherichia coli 0.04 0.04 1 PMID:20617848 -6.1.1.24 trnagln methanothermobacter thermautotrophicus 0.1 0.1 1 PMID:20617848 -6.1.1.24 trnagln thermosynechococcus vestitus 0.036 0.036 1 PMID:16876193 -6.1.1.24 trnaglu bacillus subtilis 0.05 0.05 1 PMID:3079749 -6.1.1.24 trnaglu thermosynechococcus vestitus 0.1 0.1 1 PMID:16876193 -6.1.1.26 2-amino-6-((r)-tetrahydrofuran-2-carboxamido)hexanoic acid methanosarcina barkeri 0.062 0.062 1 PMID:19063902 -6.1.1.26 2-amino-6-(cyclopentanecarboxamido)hexanoic acid methanosarcina barkeri 0.04 0.04 1 PMID:19063902 -6.1.1.26 l-pyrrolysine desulfitobacterium hafniense 0.325 0.325 1 PMID:22851181 -6.1.1.26 l-pyrrolysine methanosarcina barkeri 0.325 0.105 3 PMID:19063902;PMID:22851181 -6.1.1.26 nepsilon-cyclopentyloxycarbonyl-l-lysine methanosarcina barkeri 0.015 0.015 1 PMID:19063902 -6.1.1.26 trnapyl desulfitobacterium hafniense 0.19 0.19 1 PMID:17267409 -6.1.1.27 m1g37-trnacys methanocaldococcus jannaschii 0.24 0.24 1 PMID:18425141 -6.1.1.27 o-phospho-l-serine methanosarcina mazei 10.6 5.5249999999999995 2 PMID:18559342 -6.1.1.27 o-phospho-l-threonine methanosarcina mazei 0.014 0.0097 2 PMID:18559342 -6.1.1.27 trnacys archaeoglobus fulgidus 0.115 0.115 2 PMID:18503748 -6.1.1.27 trnacys methanocaldococcus jannaschii 1.0 0.24 3 PMID:18425141 -6.1.1.27 trnacys methanococcus maripaludis 0.07 0.07 1 PMID:25002468 -6.1.1.27 trnacys methanosarcina mazei 0.12 0.12 1 PMID:18559341 -6.1.1.3 atp escherichia coli 90.0 90.0 1 PMID:14690420 -6.1.1.3 atp mus musculus 25.6 6.965 6 PMID:29579307 -6.1.1.3 hydroxynorvaline escherichia coli 22.0 21.5 2 PMID:10881191 -6.1.1.3 l-serine [mycoplasma] mobile 0.55 0.55 1 PMID:27542414 -6.1.1.3 l-serine escherichia coli 30.0 28.0 2 PMID:10881191 -6.1.1.3 l-serine methanocaldococcus jannaschii 1.3 1.3 1 PMID:15240874 -6.1.1.3 l-serine mycoplasma capricolum 1.15 1.15 1 PMID:27542414 -6.1.1.3 l-serine saccharolobus solfataricus 12.3 12.3 1 PMID:15240874 -6.1.1.3 l-serine saccharomyces cerevisiae 1.83 1.83 1 PMID:22773845 -6.1.1.3 l-threonine [mycoplasma] mobile 2.16 2.16 1 PMID:27542414 -6.1.1.3 l-threonine archaeoglobus fulgidus 3.8 3.8 1 PMID:15507440 -6.1.1.3 l-threonine escherichia coli 90.0 35.0 5 PMID:10881191;PMID:14690420;PMID:15507440;PMID:25128830 -6.1.1.3 l-threonine methanocaldococcus jannaschii 1.9 1.5499999999999998 2 PMID:15240874;PMID:15507440 -6.1.1.3 l-threonine mus musculus 0.37 0.37 3 PMID:29579307 -6.1.1.3 l-threonine mycoplasma capricolum 6.31 6.31 1 PMID:27542414 -6.1.1.3 l-threonine saccharolobus solfataricus 16.0 14.75 2 PMID:15240874;PMID:15507440 -6.1.1.3 l-threonine saccharomyces cerevisiae 3.32 3.32 1 PMID:22773845 -6.1.1.3 l-threonyl-trnathr saccharomyces pastorianus 1.73 1.73 1 PMID:670153 -6.1.1.3 trna1thr saccharomyces cerevisiae 0.05 0.05 1 PMID:22343532 -6.1.1.3 trna2thr saccharomyces cerevisiae 0.038 0.038 1 PMID:22343532 -6.1.1.3 trnathr escherichia coli 0.7 0.53 3 PMID:20160114;PMID:8031907 -6.1.1.3 trnathr saccharomyces cerevisiae 0.0467 0.0383 3 PMID:21321019 -6.1.1.3 trnathr thermus thermophilus 0.23 0.22 2 PMID:8031907 -6.1.1.3 trnathr1 saccharomyces cerevisiae 0.0338 0.0338 1 PMID:25414329 -6.1.1.4 atp aquifex aeolicus 14.5 2.005 8 PMID:11997034;PMID:12196521;PMID:15177296;PMID:17144674 -6.1.1.4 atp escherichia coli 5.0 4.550000000000001 6 PMID:10024478;PMID:10828991;PMID:11170439;PMID:12739900;PMID:15110746 -6.1.1.4 atp giardia duodenalis 3.1 3.1 1 PMID:19170608 -6.1.1.4 atp homo sapiens 0.8 0.74 5 PMID:10684970;PMID:16055448 -6.1.1.4 atp pseudomonas aeruginosa 46.9 46.9 1 PMID:30088448 -6.1.1.4 atp pyrococcus horikoshii 6.8 6.8 1 PMID:20482517 -6.1.1.4 ile-trnaleu escherichia coli 7.0 7.0 1 PMID:23035846 -6.1.1.4 l-isoleucine aquifex aeolicus 1.9 1.9 1 PMID:19068478 -6.1.1.4 l-isoleucine escherichia coli 18.0 9.05 2 PMID:10828991;PMID:15723544 -6.1.1.4 l-isoleucine homo sapiens 0.34 0.20500000000000002 2 PMID:15723544;PMID:19702327 -6.1.1.4 l-isoleucine saccharomyces cerevisiae 10.2 10.2 1 PMID:18550527 -6.1.1.4 l-isoleucyl-trnaleu giardia duodenalis 1.52 1.52 1 PMID:19540202 -6.1.1.4 l-leucine aquifex aeolicus 26.3 1.4849999999999999 10 PMID:11997034;PMID:12196521;PMID:15177296;PMID:17144674;PMID:18367476;PMID:19068478 -6.1.1.4 l-leucine escherichia coli 171.0 5.15 10 PMID:10024478;PMID:10828991;PMID:11170439;PMID:12739900;PMID:14705941;PMID:15110746;PMID:15723544;PMID:23035846 -6.1.1.4 l-leucine giardia duodenalis 2.8 2.75 2 PMID:19170608;PMID:19540202 -6.1.1.4 l-leucine homo sapiens 25.8 1.41 8 PMID:10684970;PMID:15723544;PMID:16055448;PMID:19702327;PMID:20805241 -6.1.1.4 l-leucine natrialba magadii 0.563 0.286305 2 PMID:24500203 -6.1.1.4 l-leucine neisseria gonorrhoeae 90.0 90.0 1 PMID:36038645 -6.1.1.4 l-leucine pseudomonas aeruginosa 59.4 59.4 1 PMID:30088448 -6.1.1.4 l-leucine pyrococcus horikoshii 6.0 6.0 1 PMID:20482517 -6.1.1.4 l-leucine saccharomyces cerevisiae 37.5 37.5 1 PMID:18550527 -6.1.1.4 l-leucyl-pyrococcus horikoshii trnaleu(gag) natrialba magadii 0.0418 0.021495 2 PMID:24500203 -6.1.1.4 l-methionine aquifex aeolicus 3.2 3.2 1 PMID:19068478 -6.1.1.4 l-methionine escherichia coli 19.0 19.0 1 PMID:10828991 -6.1.1.4 l-norvaline aquifex aeolicus 12.6 12.6 1 PMID:19068478 -6.1.1.4 leu neurospora crassa 50.0 26.85 2 PMID:2942398 -6.1.1.4 leu-trnaleu cyberlindnera jadinii 23.8 23.8 1 PMID:1100400 -6.1.1.4 leu-trnaleu phaseolus vulgaris 3.15 2.5999999999999996 2 PMID:6630191;PMID:7050099 -6.1.1.4 natrialba magadii trnaleu(caa) natrialba magadii 0.0464 0.023409 2 PMID:24500203 -6.1.1.4 natrialba magadii trnaleu(gag) natrialba magadii 0.064 0.032334 2 PMID:24500203 -6.1.1.4 norvaline saccharomyces cerevisiae 13.5 13.5 1 PMID:18550527 -6.1.1.4 trnacagleu homo sapiens 2.6 2.6 1 PMID:25817995 -6.1.1.4 trnagagleu aquifex aeolicus 1.5 1.5 1 PMID:25817995 -6.1.1.4 trnagagleu escherichia coli 4.9 4.9 1 PMID:25817995 -6.1.1.4 trnagagleu pyrococcus horikoshii 0.02 0.02 1 PMID:25817995 -6.1.1.4 trnaleu aquifex aeolicus 0.5 0.41000000000000003 2 PMID:15161932;PMID:15208367 -6.1.1.4 trnaleu escherichia coli 9.6 4.45 8 PMID:10024478;PMID:10828991;PMID:11170439;PMID:12739900;PMID:15110746;PMID:17311409;PMID:17407263 -6.1.1.4 trnaleu giardia duodenalis 2.7 2.7 1 PMID:19170608 -6.1.1.4 trnaleu homo sapiens 0.12 0.059 3 PMID:10684970;PMID:16055448 -6.1.1.4 trnaleu mycobacterium tuberculosis 7.8 7.8 1 PMID:23268443 -6.1.1.4 trnaleu pseudomonas aeruginosa 0.44 0.44 1 PMID:30088448 -6.1.1.4 trnaleu pyrococcus horikoshii 0.331 0.331 1 PMID:17407269 -6.1.1.4 trnaleu saccharomyces cerevisiae 5.0 5.0 1 PMID:17270210 -6.1.1.4 trnaleu from aquifex aeolicus aquifex aeolicus 1.5 0.39 3 PMID:11997034;PMID:12196521 -6.1.1.4 trnaleu from escherichia coli aquifex aeolicus 0.4 0.084 3 PMID:11997034;PMID:12196521 -6.1.1.4 trnaleu(gag) [mycoplasma] mobile 1.8 1.8 1 PMID:23525458 -6.1.1.4 trnaleu(gag) aquifex aeolicus 1.59 1.5350000000000001 2 PMID:15177296 -6.1.1.4 trnaleu(uaa) escherichia coli 6.1 4.65 2 PMID:14705941;PMID:16300391 -6.1.1.4 trnaleu(uag) [mycoplasma] mobile 2.0 2.0 1 PMID:23525458 -6.1.1.4 trnaleua35g aquifex aeolicus 0.31 0.31 1 PMID:15161932 -6.1.1.4 trnaleua73g aquifex aeolicus 0.11 0.11 1 PMID:15161932 -6.1.1.4 trnaleucun escherichia coli 14.5 14.5 1 PMID:17378584 -6.1.1.4 trnaleucun homo sapiens 0.39 0.39 1 PMID:17378584 -6.1.1.4 trnaleugag aquifex aeolicus 1.5 1.5 1 PMID:17144674 -6.1.1.4 trnaleuuur escherichia coli 0.00016 0.00016 1 PMID:17378584 -6.1.1.4 trnaleuuur homo sapiens 0.09 0.09 1 PMID:17378584 -6.1.1.4 trnauaaleu [mycoplasma] mobile 3.3 3.3 1 PMID:25817995 -6.1.1.4 trnauaaleu escherichia coli 4.2 4.2 1 PMID:25817995 -6.1.1.5 amp saccharomyces cerevisiae 0.2 0.2 1 PMID:26921320 -6.1.1.5 amp streptomyces griseus 0.64 0.64 1 PMID:26921320 -6.1.1.5 atp escherichia coli 80.4 40.980000000000004 2 PMID:20498377;PMID:8672449 -6.1.1.5 isoleucine escherichia coli 104.0 65.85 2 PMID:7488160;PMID:7947832 -6.1.1.5 l-isoleucine escherichia coli 55.0 55.0 3 PMID:25207837;PMID:30711543 -6.1.1.5 l-isoleucine pseudomonas fluorescens 6.0 3.3 5 PMID:12672810 -6.1.1.5 l-isoleucine staphylococcus aureus 18.0 9.175 2 PMID:9822629 -6.1.1.5 l-norvaline escherichia coli 35.0 33.0 2 PMID:30711543 -6.1.1.5 l-valine escherichia coli 41.0 33.0 2 PMID:30711543 -6.1.1.5 trnaile escherichia coli 3.1 3.1 1 PMID:7488160 -6.1.1.5 trnaile saccharomyces cerevisiae 0.13 0.13 1 PMID:26921320 -6.1.1.5 trnaile streptomyces griseus 0.65 0.65 1 PMID:26921320 -6.1.1.5 trnaile1 lacticaseibacillus casei 0.0011 0.0011 1 PMID:35122395 -6.1.1.5 trnaile2 lacticaseibacillus casei 0.00024 0.00024 1 PMID:35122395 -6.1.1.6 atp borreliella burgdorferi 0.57 0.57 1 PMID:16533047 -6.1.1.6 atp cricetinae 5.1 5.05 2 PMID:11706011 -6.1.1.6 atp escherichia coli 3.4 3.4 1 PMID:15362869 -6.1.1.6 atp geobacillus stearothermophilus 42.8 41.849999999999994 2 PMID:12507472;PMID:8743569 -6.1.1.6 atp pseudomonas aeruginosa 22.8 22.8 1 PMID:31498734 -6.1.1.6 borellia burgdorferi trnalys borreliella burgdorferi 6.08 3.435 2 PMID:9892648 -6.1.1.6 borellia burgdorferi trnalys escherichia coli 0.0035 0.0035 1 PMID:9892648 -6.1.1.6 escherichia coli g2.u71 trna borreliella burgdorferi 0.0035 0.0035 1 PMID:9892648 -6.1.1.6 escherichia coli g2.u71 trna escherichia coli 0.0025 0.0025 1 PMID:9892648 -6.1.1.6 escherichia coli trnalys methanococcus maripaludis 0.004 0.004 1 PMID:9892648 -6.1.1.6 escherichia coli trnalys cnbr-treated methanococcus maripaludis 0.002 0.002 1 PMID:9892648 -6.1.1.6 escherichia coli wild type trnalys borreliella burgdorferi 0.004 0.004 1 PMID:9892648 -6.1.1.6 escherichia coli wild type trnalys escherichia coli 0.055 0.055 1 PMID:9892648 -6.1.1.6 human trnalys3 cricetinae 7.8 7.0 2 PMID:11706011 -6.1.1.6 l-arginyl-trnalys escherichia coli 0.00067 0.00067 1 PMID:10387054 -6.1.1.6 l-lysine bacillus cereus 41.7 41.7 1 PMID:21925499 -6.1.1.6 l-lysine borreliella burgdorferi 0.34 0.34 1 PMID:16533047 -6.1.1.6 l-lysine cricetinae 5.8 5.449999999999999 2 PMID:11706011 -6.1.1.6 l-lysine escherichia coli 1.8 0.900325 2 PMID:10387054;PMID:15362869 -6.1.1.6 l-lysine geobacillus stearothermophilus 45.7 3.53 7 PMID:10737207;PMID:12507472;PMID:8743569;PMID:9644244 -6.1.1.6 l-lysine methanothermobacter thermautotrophicus 0.0143 0.0143 1 PMID:17158871 -6.1.1.6 l-lysine pseudomonas aeruginosa 13.0 13.0 1 PMID:31498734 -6.1.1.6 l-lysine amide geobacillus stearothermophilus 14.5 14.5 1 PMID:9644244 -6.1.1.6 l-lysine hydroxamate geobacillus stearothermophilus 221.0 221.0 1 PMID:9644244 -6.1.1.6 l-lysyl-trnalys escherichia coli 0.0088 0.004515 2 PMID:10387054 -6.1.1.6 l-methionyl-trnalys escherichia coli 0.00056 0.00056 1 PMID:10387054 -6.1.1.6 l-threonyl-trnalys escherichia coli 0.00076 0.00076 1 PMID:10387054 -6.1.1.6 methanococcus maripaludis trnalys methanococcus maripaludis 0.2 0.2 1 PMID:9892648 -6.1.1.6 methanococcus maripaludis trnalys cnbr-treated methanococcus maripaludis 0.05 0.05 1 PMID:9892648 -6.1.1.6 trnalys borreliella burgdorferi 0.34 0.34 1 PMID:15862301 -6.1.1.6 trnalys homo sapiens 2.0 1.85 2 PMID:10572184 -6.1.1.6 trnalys pseudomonas aeruginosa 0.35 0.35 1 PMID:31498734 -6.1.1.6 trnalys rattus norvegicus 5.5 4.1 2 PMID:3753009 -6.1.1.6 trnalyscuu borreliella burgdorferi 0.014 0.014 1 PMID:11121028 -6.1.1.6 trnalyscuu pyrococcus horikoshii 0.062 0.062 1 PMID:17760422 -6.1.1.6 trnalysguu borreliella burgdorferi 0.0095 0.0095 1 PMID:11121028 -6.1.1.6 trnalysguu pyrococcus horikoshii 0.043 0.043 1 PMID:17760422 -6.1.1.6 trnalysugu borreliella burgdorferi 0.0004 0.0004 1 PMID:11121028 -6.1.1.6 trnalysuuc borreliella burgdorferi 0.00018 0.00018 1 PMID:11121028 -6.1.1.6 trnalysuuu borreliella burgdorferi 0.33 0.16975 2 PMID:11121028;PMID:16533047 -6.1.1.6 trnalysuuu pyrococcus horikoshii 0.44 0.44 1 PMID:17760422 -6.1.1.6 trnalysuuumodified borreliella burgdorferi 0.12 0.12 1 PMID:11121028 -6.1.1.6 trnatyrcua escherichia coli 0.013 0.013 1 PMID:16672269 -6.1.1.6 yeast trnalys cricetinae 7.1 6.699999999999999 2 PMID:11706011 -6.1.1.7 atp escherichia coli 120.0 89.0 3 PMID:7918446;PMID:8239663 -6.1.1.7 atp homo sapiens 1.9 1.9 1 PMID:30952159 -6.1.1.7 glycine escherichia coli 3.7 3.7 1 PMID:20010690 -6.1.1.7 l-alanine escherichia coli 26.67 16.0 3 PMID:20010690;PMID:35065077 -6.1.1.7 l-alanine homo sapiens 0.067 0.067 1 PMID:30952159 -6.1.1.7 l-serine escherichia coli 2.4 2.4 1 PMID:20010690 -6.1.1.7 lipid ii l-ala streptococcus pneumoniae 0.071 0.06725 2 PMID:18842590 -6.1.1.7 lipid ii l-ser streptococcus pneumoniae 0.0166 0.0166 2 PMID:18842590 -6.1.1.7 tmrna escherichia coli 0.043 0.043 1 PMID:10704215 -6.1.1.7 tmrna thermus thermophilus 0.1 0.1 1 PMID:12542696 -6.1.1.7 trnaala escherichia coli 2.0 0.32 6 PMID:10704215;PMID:10889033;PMID:16843487;PMID:35065077;PMID:8239663 -6.1.1.7 trnaala thermus thermophilus 2.2 2.2 1 PMID:12542696 -6.1.1.7 trnaphe escherichia coli 0.25 0.25 1 PMID:10889033 -6.1.1.9 atp escherichia coli 50.0 31.45 2 PMID:12475234;PMID:20498377 -6.1.1.9 l-norvaline escherichia coli 4.3 4.3 1 PMID:30711543 -6.1.1.9 l-valine anabaena sp. 0.074 0.074 1 PMID:21965654 -6.1.1.9 l-valine escherichia coli 13.9 7.7 2 PMID:12475234;PMID:14970394 -6.1.1.9 l-valyl-trnaval saccharomyces cerevisiae 0.2 0.2 1 PMID:18755686 -6.1.1.9 trnaval escherichia coli 51.0 26.35 2 PMID:12475234 -6.1.1.9 trnaval thermus thermophilus 6.7 6.7 1 PMID:12554880 -6.1.1.9 valine geobacillus stearothermophilus 5.65 4.275 2 PMID:3770480 -6.1.2.1 d-2-hydroxybutanoate enterococcus faecalis 0.25 0.25 1 PMID:7957913 -6.1.2.1 d-2-hydroxybutanoate enterococcus faecium 1.8 1.8 1 PMID:1931965 -6.1.2.1 d-2-hydroxyvalerate enterococcus faecalis 0.42 0.42 1 PMID:7957913 -6.1.2.1 d-2-hydroxyvalerate enterococcus faecium 2.6 2.6 1 PMID:1931965 -6.1.2.1 d-ala enterococcus faecalis 4.1 4.1 1 PMID:7957913 -6.1.2.1 d-ala enterococcus faecium 4.92 4.92 1 PMID:1931965 -6.1.2.1 d-ala escherichia coli 15.7 15.35 2 PMID:8756703 -6.1.2.1 d-lactate enterococcus faecalis 0.47 0.47 1 PMID:7957913 -6.1.2.1 d-lactate enterococcus faecium 1.57 1.57 1 PMID:1931965 -6.1.2.1 d-lactate escherichia coli 1.17 0.67 3 PMID:8756703 -6.1.3.1 (2r,3r)-2-hexyl-3-hydroxydecanoic acid stenotrophomonas maltophilia 0.01 0.01 1 PMID:27238740 -6.1.3.1 (2r,3s)-2-hexyl-3-hydroxydecanoic acid stenotrophomonas maltophilia 0.0245 0.0245 1 PMID:27238740 -6.1.3.1 (2s,3r)-2-hexyl-3-hydroxydecanoic acid stenotrophomonas maltophilia 0.006 0.006 1 PMID:27238740 -6.1.3.1 (2s,3s)-2-hexyl-3-hydroxydecanoic acid stenotrophomonas maltophilia 0.0301 0.0301 1 PMID:27238740 -6.2.1.1 acetate arabidopsis thaliana 5.7 4.055 2 PMID:31117358 -6.2.1.1 acetate archaeoglobus fulgidus 21.2 21.2 1 PMID:17350930 -6.2.1.1 acetate escherichia coli 76.7 38.67 2 PMID:30928490 -6.2.1.1 acetate methanothermobacter thermautotrophicus 66.6 65.4 3 PMID:16981708;PMID:17350930;PMID:22973162 -6.2.1.1 acetate saccharopolyspora erythraea 77.5 52.7 3 PMID:27987242 -6.2.1.1 acetate salmonella enterica 9400.0 9400.0 1 PMID:21306440 -6.2.1.1 atp archaeoglobus fulgidus 13.2 13.2 1 PMID:17350930 -6.2.1.1 atp escherichia coli 115.0 57.935 2 PMID:30928490 -6.2.1.1 atp methanothermobacter thermautotrophicus 66.6 66.6 3 PMID:17350930;PMID:22973162 -6.2.1.1 atp salmonella enterica 100.6 51.15 2 PMID:17497934 -6.2.1.1 butyrate archaeoglobus fulgidus 0.013 0.013 1 PMID:17350930 -6.2.1.1 coa archaeoglobus fulgidus 144.9 144.9 1 PMID:17350930 -6.2.1.1 coa methanothermobacter thermautotrophicus 81.6 74.1 2 PMID:17350930;PMID:22973162 -6.2.1.1 coa salmonella enterica 95.1 49.15 2 PMID:17497934 -6.2.1.1 potassium acetate chromochloris zofingiensis 69.96 67.37 2 PMID:31385495 -6.2.1.1 propionate arabidopsis thaliana 0.66 0.66 1 PMID:31117358 -6.2.1.1 propionate archaeoglobus fulgidus 9.1 9.1 1 PMID:17350930 -6.2.1.1 propionate methanothermobacter thermautotrophicus 46.3 46.3 2 PMID:16981708;PMID:17350930 -6.2.1.1 sodium acetate chromochloris zofingiensis 60.93 55.54 2 PMID:31385495 -6.2.1.12 3,4-methylenedioxycinnamate piper nigrum 2.72 2.72 1 PMID:31764941 -6.2.1.12 4-coumarate anthoceros agrestis 2.5 2.0 2 PMID:32405654 -6.2.1.12 4-coumarate nicotiana tabacum 3.978 3.978 1 PMID:26412334 -6.2.1.12 4-coumarate ocimum tenuiflorum 1.0 1.0 1 PMID:23677922 -6.2.1.12 4-coumarate oryza sativa 0.285 0.047 5 PMID:21807887 -6.2.1.12 4-coumarate pinus taeda 4.15 2.1700000000000004 2 PMID:25016610 -6.2.1.12 4-coumarate piper nigrum 0.81 0.755 2 PMID:31764941 -6.2.1.12 4-coumarate plagiochasma appendiculatum 0.216 0.216 1 PMID:25593011 -6.2.1.12 4-coumarate populus tomentosa 88.68 4.55 5 * -6.2.1.12 4-coumarate populus trichocarpa 13.91 8.04 2 PMID:31233773 -6.2.1.12 4-coumarate pueraria montana var. lobata 1.28 1.15 2 PMID:24141262 -6.2.1.12 4-coumarate solanum lycopersicum 4.05 1.1825 6 PMID:21883557 -6.2.1.12 4-coumarate sorbus aucuparia 1.0 0.96 3 PMID:21330005 -6.2.1.12 atp anthoceros agrestis 1.9 1.5 2 PMID:32405654 -6.2.1.12 caffeate anthoceros agrestis 2.0 1.55 2 PMID:32405654 -6.2.1.12 caffeate nicotiana tabacum 2.652 2.652 1 PMID:26412334 -6.2.1.12 caffeate ocimum tenuiflorum 0.44 0.44 1 PMID:23677922 -6.2.1.12 caffeate oryza sativa 0.255 0.036 5 PMID:21807887 -6.2.1.12 caffeate pinus taeda 1.6 0.865 2 PMID:25016610 -6.2.1.12 caffeate plagiochasma appendiculatum 0.084 0.084 1 PMID:25593011 -6.2.1.12 caffeate populus tomentosa 31.4 5.81 5 * -6.2.1.12 caffeate populus trichocarpa 5.5 3.2199999999999998 2 PMID:31233773 -6.2.1.12 caffeate pueraria montana var. lobata 0.92 0.92 1 PMID:24141262 -6.2.1.12 caffeate sorbus aucuparia 0.8 0.78 3 PMID:21330005 -6.2.1.12 cinnamate anthoceros agrestis 1.8 1.4 2 PMID:32405654 -6.2.1.12 cinnamate oryza sativa 0.182 0.0188 5 PMID:21807887 -6.2.1.12 cinnamate pinus taeda 5.22 2.745 2 PMID:25016610 -6.2.1.12 cinnamate piper nigrum 0.19 0.19 1 PMID:31764941 -6.2.1.12 cinnamate populus tomentosa 3.22 1.17 5 * -6.2.1.12 cinnamate sorbus aucuparia 0.37 0.3 3 PMID:21330005 -6.2.1.12 coa acetobacterium woodii 5.5 5.5 1 PMID:21131487 -6.2.1.12 coa anthoceros agrestis 2.5 1.75 2 PMID:32405654 -6.2.1.12 dihydro-4-coumarate plagiochasma appendiculatum 0.084 0.084 1 PMID:25593011 -6.2.1.12 ferulate anthoceros agrestis 3.1 2.35 2 PMID:32405654 -6.2.1.12 ferulate nicotiana tabacum 3.576 3.576 1 PMID:26412334 -6.2.1.12 ferulate ocimum tenuiflorum 1.56 1.56 1 PMID:23677922 -6.2.1.12 ferulate oryza sativa 0.299 0.034 5 PMID:21807887 -6.2.1.12 ferulate pinus taeda 14.99 7.57 2 PMID:25016610 -6.2.1.12 ferulate piper nigrum 1.09 0.805 2 PMID:31764941 -6.2.1.12 ferulate populus tomentosa 126.47 4.19 5 * -6.2.1.12 ferulate populus trichocarpa 4.65 2.7300000000000004 2 PMID:31233773 -6.2.1.12 ferulate pueraria montana var. lobata 0.57 0.57 1 PMID:24141262 -6.2.1.12 ferulate solanum lycopersicum 2.04 1.063 5 PMID:21883557 -6.2.1.12 ferulate sorbus aucuparia 0.49 0.38 3 PMID:21330005 -6.2.1.12 isoferulate anthoceros agrestis 1.7 1.25 2 PMID:32405654 -6.2.1.12 piperate piper nigrum 2.91 2.91 1 PMID:31764941 -6.2.1.12 sinapate oryza sativa 0.053 0.053 1 PMID:21807887 -6.2.1.12 sinapinate nicotiana tabacum 0.018 0.018 1 PMID:26412334 -6.2.1.12 trans-cinnamate ocimum tenuiflorum 0.58 0.58 1 PMID:23677922 -6.2.1.12 trans-cinnamate populus trichocarpa 0.62 0.45 2 PMID:31233773 -6.2.1.12 trans-cinnamate pueraria montana var. lobata 0.97 0.72 2 PMID:24141262 -6.2.1.13 acetate entamoeba histolytica 240.0 46.0 5 PMID:25303954;PMID:26922831;PMID:28129670 -6.2.1.13 acetate pyrococcus furiosus 67.0 67.0 1 PMID:8830684 -6.2.1.13 acetate thermococcus kodakarensis 49.3 49.3 1 PMID:24163338 -6.2.1.13 acetyl-coa entamoeba histolytica 111.0 55.0 5 PMID:25303954;PMID:26922831;PMID:28129670 -6.2.1.13 acetyl-coa pyrococcus furiosus 157.0 99.5 2 PMID:8830684 -6.2.1.13 adp entamoeba histolytica 140.0 86.0 4 PMID:25303954;PMID:26922831;PMID:28129670 -6.2.1.13 adp pyrococcus furiosus 203.0 159.0 2 PMID:8830684 -6.2.1.13 atp entamoeba histolytica 320.0 280.0 4 PMID:25303954;PMID:26922831;PMID:28129670 -6.2.1.13 atp pyrococcus furiosus 82.0 75.0 2 PMID:8830684 -6.2.1.13 atp thermococcus kodakarensis 53.7 53.7 1 PMID:24163338 -6.2.1.13 coa entamoeba histolytica 328.0 240.0 4 PMID:25303954;PMID:26922831;PMID:28129670 -6.2.1.13 coa pyrococcus furiosus 73.0 70.0 3 PMID:8830684 -6.2.1.13 coa thermococcus kodakarensis 53.1 53.1 1 PMID:24163338 -6.2.1.13 gdp entamoeba histolytica 170.0 170.0 1 PMID:25303954 -6.2.1.13 gdp pyrococcus furiosus 411.0 216.0 2 PMID:8830684 -6.2.1.13 gtp entamoeba histolytica 180.0 180.0 1 PMID:25303954 -6.2.1.13 gtp pyrococcus furiosus 27.0 27.0 1 PMID:8830684 -6.2.1.13 indoleacetate pyrococcus furiosus 66.0 66.0 1 PMID:8830684 -6.2.1.13 isobutyrate pyrococcus furiosus 55.0 38.5 2 PMID:8830684 -6.2.1.13 isobutyrate thermococcus kodakarensis 50.9 50.9 1 PMID:24163338 -6.2.1.13 isobutyryl-coa pyrococcus furiosus 121.0 64.5 2 PMID:8830684 -6.2.1.13 phenylacetate pyrococcus furiosus 89.0 89.0 1 PMID:8830684 -6.2.1.13 phenylacetate thermococcus kodakarensis 40.6 40.6 1 PMID:24163338 -6.2.1.13 phenylacetyl-coa pyrococcus furiosus 138.0 138.0 1 PMID:8830684 -6.2.1.13 phosphate entamoeba histolytica 120.0 74.5 4 PMID:25303954;PMID:26922831;PMID:28129670 -6.2.1.13 phosphate pyrococcus furiosus 182.0 149.5 2 PMID:8830684 -6.2.1.13 propionate entamoeba histolytica 190.0 190.0 1 PMID:25303954 -6.2.1.13 propionyl-coa entamoeba histolytica 21.0 21.0 1 PMID:25303954 -6.2.1.13 thioglycolate thermococcus kodakarensis 26.1 26.1 1 PMID:24163338 -6.2.1.14 6-carboxyhexanoate aquifex aeolicus 7.45 7.45 1 PMID:28414711 -6.2.1.14 6-carboxyhexanoate bacillus subtilis 0.48 0.48 1 PMID:28414710 -6.2.1.14 6-carboxyhexanoate corynebacterium amycolatum 0.21 0.21 1 PMID:35695820 -6.2.1.14 adipate bacillus subtilis 0.0066 0.0066 1 PMID:28414710 -6.2.1.14 atp bacillus subtilis 0.44 0.44 1 PMID:28414710 -6.2.1.14 azelate bacillus subtilis 0.0001 0.0001 1 PMID:28414710 -6.2.1.14 coa bacillus subtilis 0.87 0.87 1 PMID:28414710 -6.2.1.14 glutarate bacillus subtilis 0.0051 0.0051 1 PMID:28414710 -6.2.1.14 suberate bacillus subtilis 0.0038 0.0038 1 PMID:28414710 -6.2.1.16 acetoacetate streptomyces lividans 5.89 5.89 1 PMID:25532451 -6.2.1.16 atp streptomyces lividans 6.43 6.43 1 PMID:25532451 -6.2.1.16 coa streptomyces lividans 8.16 8.16 1 PMID:25532451 -6.2.1.17 3-hydroxypropanoate metallosphaera sedula 23.0 23.0 1 PMID:18165310 -6.2.1.17 3-hydroxypropanoate sulfurisphaera tokodaii 8.0 8.0 1 PMID:18165310 -6.2.1.17 3-hydroxypropionate chloroflexus aurantiacus 12.0 12.0 1 PMID:11821399 -6.2.1.17 acetate ralstonia solanacearum 6.8 6.8 2 PMID:14706841 -6.2.1.17 acetate salmonella enterica 32.0 4.8 3 PMID:11841231;PMID:14706841 -6.2.1.17 acrylate metallosphaera sedula 5.4 5.4 1 PMID:18165310 -6.2.1.17 acrylate ralstonia solanacearum 1.3 1.3 2 PMID:14706841 -6.2.1.17 acrylate salmonella enterica 26.0 1.1 3 PMID:11841231;PMID:14706841 -6.2.1.17 atp ralstonia solanacearum 1.5 1.5 2 PMID:14706841 -6.2.1.17 atp salmonella enterica 34.0 1.1 3 PMID:11841231;PMID:14706841 -6.2.1.17 butyrate ralstonia solanacearum 1.7 1.7 2 PMID:14706841 -6.2.1.17 butyrate salmonella enterica 6.0 0.87 3 PMID:11841231;PMID:14706841 -6.2.1.17 coa ralstonia solanacearum 2.4 2.4 2 PMID:14706841 -6.2.1.17 coa salmonella enterica 42.0 1.0 3 PMID:11841231;PMID:14706841 -6.2.1.17 diphosphate salmonella enterica 79.0 79.0 1 PMID:11841231 -6.2.1.17 propanoate metallosphaera sedula 5.6 5.6 1 PMID:18165310 -6.2.1.17 propionate ralstonia solanacearum 1.8 1.8 2 PMID:14706841 -6.2.1.17 propionate salmonella enterica 33.0 1.2 3 PMID:11841231;PMID:14706841 -6.2.1.17 propionyl-amp salmonella enterica 78.0 78.0 1 PMID:11841231 -6.2.1.2 2-methylbutyrate methanosarcina acetivorans 1.58 1.58 1 PMID:20851904 -6.2.1.2 atp methanosarcina acetivorans 1.94 1.94 1 PMID:20851904 -6.2.1.2 atp penicillium chrysogenum 42.9 22.3 2 PMID:18834333 -6.2.1.2 coa methanosarcina acetivorans 2.15 2.15 1 PMID:20851904 -6.2.1.2 coa penicillium chrysogenum 60.5 31.0 2 PMID:18834333 -6.2.1.2 phenoxyacetate penicillium chrysogenum 12.0 12.0 1 PMID:18834333 -6.2.1.2 phenylacetate penicillium chrysogenum 1.9 1.9 1 PMID:18834333 -6.2.1.2 trans-cinnamic acid penicillium chrysogenum 41.2 41.2 1 PMID:18834333 -6.2.1.20 oleic acid synechococcus elongatus 0.016 0.016 1 PMID:20061450 -6.2.1.25 1-cyclohexene-carboxylate rhodopseudomonas palustris 5.6 5.6 1 PMID:26378464 -6.2.1.25 2-aminobenzoate rhodopseudomonas palustris 3.9 3.9 1 PMID:26378464 -6.2.1.25 2-chlorobenzoate rhodopseudomonas palustris 2.2 2.2 1 PMID:26378464 -6.2.1.25 2-cyanobenzoate rhodopseudomonas palustris 0.11 0.11 1 PMID:26378464 -6.2.1.25 2-fluorobenzoate rhodopseudomonas palustris 34.0 34.0 1 PMID:26378464 -6.2.1.25 2-hydroxybenzoate rhodopseudomonas palustris 0.63 0.63 1 PMID:26378464 -6.2.1.25 2-methoxybenzoate rhodopseudomonas palustris 0.011 0.011 1 PMID:26378464 -6.2.1.25 2-methylbenzoate rhodopseudomonas palustris 1.2 1.2 1 PMID:26378464 -6.2.1.25 2-nitrobenzoate rhodopseudomonas palustris 0.27 0.27 1 PMID:26378464 -6.2.1.25 3-aminobenzoate rhodopseudomonas palustris 1.8 1.8 1 PMID:26378464 -6.2.1.25 3-chlorobenzoate rhodopseudomonas palustris 0.33 0.33 1 PMID:26378464 -6.2.1.25 3-cyclohexene-carboxylate rhodopseudomonas palustris 16.0 16.0 1 PMID:26378464 -6.2.1.25 3-fluorobenzoate rhodopseudomonas palustris 35.0 35.0 1 PMID:26378464 -6.2.1.25 3-furoate rhodopseudomonas palustris 6.7 6.7 1 PMID:26378464 -6.2.1.25 3-hydroxybenzoate rhodopseudomonas palustris 1.8 1.8 1 PMID:26378464 -6.2.1.25 3-methylbenzoate rhodopseudomonas palustris 0.54 0.54 1 PMID:26378464 -6.2.1.25 4-aminobenzoate rhodopseudomonas palustris 0.18 0.18 1 PMID:26378464 -6.2.1.25 4-chlorobenzoate rhodopseudomonas palustris 0.29 0.29 1 PMID:26378464 -6.2.1.25 4-fluorobenzoate rhodopseudomonas palustris 22.0 22.0 1 PMID:26378464 -6.2.1.25 4-hydroxybenzoate rhodopseudomonas palustris 0.93 0.93 1 PMID:26378464 -6.2.1.25 4-methylbenzoate rhodopseudomonas palustris 0.7 0.7 1 PMID:26378464 -6.2.1.25 benzoate pseudomonas sp. 433.0 433.0 1 PMID:1885526 -6.2.1.25 benzoate rhodopseudomonas palustris 8.0 8.0 1 PMID:26378464 -6.2.1.25 cyclohexane carboxylate rhodopseudomonas palustris 13.5 13.5 1 PMID:26378464 -6.2.1.25 thiophene-2-carboxylate rhodopseudomonas palustris 4.8 4.8 1 PMID:26378464 -6.2.1.26 2-succinylbenzoate bacillus anthracis 2.62 2.62 1 PMID:18973344 -6.2.1.26 2-succinylbenzoate bacillus subtilis 120.0 120.0 1 PMID:26276389 -6.2.1.26 atp bacillus anthracis 2.62 2.62 1 PMID:18973344 -6.2.1.26 atp bacillus subtilis 105.0 105.0 1 PMID:26276389 -6.2.1.26 coa bacillus anthracis 2.62 2.62 1 PMID:18973344 -6.2.1.26 coa bacillus subtilis 121.7 121.7 1 PMID:26276389 -6.2.1.27 4-hydroxybenzoate anthoceros agrestis 1.1 1.1 1 PMID:32405654 -6.2.1.27 4-hydroxybenzoate pseudomonas sp. 30.0 30.0 1 PMID:8477728 -6.2.1.27 4-hydroxybenzoate thauera aromatica 24.0 24.0 1 PMID:18156265 -6.2.1.27 atp anthoceros agrestis 1.6 1.6 1 PMID:32405654 -6.2.1.27 coa anthoceros agrestis 2.2 2.2 1 PMID:32405654 -6.2.1.3 atp escherichia coli 0.029 0.029 1 PMID:12034706 -6.2.1.3 lauric acid nipponoluciola cruciata 0.651 0.651 1 PMID:15849423 -6.2.1.3 lauric acid photinus pyralis 0.278 0.278 1 PMID:15849423 -6.2.1.3 tetradecanoate trypanosoma brucei 1.2 1.1 3 PMID:11535136 -6.2.1.30 3-chlorophenylacetate burkholderia cenocepacia 1.67 1.635 2 PMID:21388965 -6.2.1.30 3-hydroxyphenylacetate burkholderia cenocepacia 2.67 2.25 2 PMID:21388965 -6.2.1.30 4-hydroxyphenylacetate burkholderia cenocepacia 1.17 1.17 1 PMID:21388965 -6.2.1.30 atp aromatoleum evansii 40.0 40.0 1 PMID:10629172 -6.2.1.30 atp penicillium chrysogenum 42.9 22.3 2 PMID:18834333 -6.2.1.30 atp pseudomonas sp. 21.7 21.7 1 PMID:8352645 -6.2.1.30 butyric acid penicillium chrysogenum 9.7 9.7 1 PMID:18834333 -6.2.1.30 caprate penicillium chrysogenum 0.102 0.102 1 PMID:21625874 -6.2.1.30 caproate penicillium chrysogenum 0.076 0.076 1 PMID:21625874 -6.2.1.30 caprylate penicillium chrysogenum 0.073 0.073 1 PMID:21625874 -6.2.1.30 coa aromatoleum evansii 40.0 40.0 1 PMID:10629172 -6.2.1.30 coa penicillium chrysogenum 60.5 31.0 2 PMID:18834333 -6.2.1.30 coa pseudomonas sp. 21.7 21.7 1 PMID:8352645 -6.2.1.30 palmitate penicillium chrysogenum 0.026 0.026 1 PMID:21625874 -6.2.1.30 phenoxyacetate penicillium chrysogenum 12.0 6.0315 2 PMID:18834333;PMID:21625874 -6.2.1.30 phenylacetate aromatoleum evansii 40.0 40.0 1 PMID:10629172 -6.2.1.30 phenylacetate burkholderia cenocepacia 5.0 4.585 2 PMID:21388965 -6.2.1.30 phenylacetate penicillium chrysogenum 1.9 0.9994999999999999 2 PMID:18834333;PMID:21625874 -6.2.1.30 phenylacetate pseudomonas sp. 21.7 21.7 1 PMID:8352645 -6.2.1.30 phenylacetate thermus thermophilus 20.0 20.0 1 PMID:18414813 -6.2.1.30 stearate penicillium chrysogenum 0.062 0.062 1 PMID:21625874 -6.2.1.30 trans-cinnamic acid penicillium chrysogenum 41.2 41.2 1 PMID:18834333 -6.2.1.32 2-aminobenzoate pseudomonas sp. 267.0 144.35 2 PMID:1885526 -6.2.1.33 4-chlorobenzoate alcaligenes sp. al3007 9.2 9.2 1 PMID:19320426 -6.2.1.33 4-chlorobenzoate pseudomonas sp. 34.0 34.0 1 PMID:9398293 -6.2.1.33 atp alcaligenes sp. al3007 11.5 11.5 1 PMID:19320426 -6.2.1.33 atp pseudomonas sp. 54.0 54.0 1 PMID:9398293 -6.2.1.33 coa alcaligenes sp. al3007 9.3 9.3 1 PMID:19320426 -6.2.1.33 coa pseudomonas sp. 39.0 39.0 1 PMID:9398293 -6.2.1.36 3-hydroxypropionate metallosphaera sedula 5.7 5.7 1 PMID:18165310 -6.2.1.36 acrylate metallosphaera sedula 5.4 5.4 1 PMID:18165310 -6.2.1.36 propionate metallosphaera sedula 5.6 5.6 1 PMID:18165310 -6.2.1.37 3-hydroxybenzoate thauera aromatica 15.0 15.0 1 PMID:18156265 -6.2.1.4 atp blastocystis hominis 0.0139 0.0139 1 PMID:27478903 -6.2.1.40 4-hydroxybutanoate metallosphaera sedula 1.8 1.8 3 PMID:23258541;PMID:24532060 -6.2.1.41 3-[(3as,4s,7as)-7a-methyl-1,5-dioxo-octahydro-1h-inden-4-yl]propanoate mycobacterium tuberculosis 7.1 7.1 1 PMID:23146019 -6.2.1.41 3aalpha-h-4a(3'-propanoate)-5alpha-hydroxy-7alphabeta-methylhexahydro-1-indanone mycobacterium tuberculosis 13.0 13.0 1 PMID:23146019 -6.2.1.41 coa mycobacterium tuberculosis 7.5 7.5 1 PMID:23146019 -6.2.1.42 3beta-hydroxy-5-cholesten-26-oate mycolicibacterium smegmatis 12.34 7.61 3 PMID:30997306 -6.2.1.43 1-naphthoate streptomyces carzinostaticus 0.11 0.11 1 PMID:17539640 -6.2.1.43 2,7-dihydroxy-5-methyl-1-naphthoate streptomyces carzinostaticus 1.55 1.55 1 PMID:17539640 -6.2.1.43 2,7-dihydroxy-5-methylnaphthalene-1-carboxylic acid streptomyces carzinostaticus 1.55 1.55 1 PMID:17539640 -6.2.1.43 2-hydroxy-1-naphthoate streptomyces carzinostaticus 0.047 0.047 1 PMID:17539640 -6.2.1.43 2-hydroxy-5,7-dimethoxy-1-naphthoate streptomyces carzinostaticus 0.42 0.42 1 PMID:17539640 -6.2.1.43 2-hydroxy-5,7-dimethoxynaphthalene-1-carboxylic acid streptomyces carzinostaticus 0.42 0.42 1 PMID:17539640 -6.2.1.43 2-hydroxy-5-methyl-1-naphthoate streptomyces carzinostaticus 0.135 0.135 1 PMID:17539640 -6.2.1.43 2-hydroxy-5-methylnaphthalene-1-carboxylic acid streptomyces carzinostaticus 0.135 0.135 1 PMID:17539640 -6.2.1.43 2-hydroxy-7-methoxy-1-naphthoate streptomyces carzinostaticus 0.118 0.118 1 PMID:17539640 -6.2.1.43 2-hydroxy-7-methoxy-5-methyl-1-naphthoate streptomyces carzinostaticus 0.63 0.63 2 PMID:17539640 -6.2.1.43 2-hydroxy-7-methoxynaphthalene-1-carboxylic acid streptomyces carzinostaticus 0.12 0.12 1 PMID:17539640 -6.2.1.43 2-hydroxynaphthalene-1-carboxylic acid streptomyces carzinostaticus 0.05 0.05 1 PMID:17539640 -6.2.1.43 naphthalene-1-carboxylic acid streptomyces carzinostaticus 0.11 0.11 1 PMID:17539640 -6.2.1.44 3-(methylthio)propanoate candidatus pelagibacter communis 29.4 29.4 1 PMID:24443527 -6.2.1.44 3-(methylthio)propanoate ruegeria pomeroyi 18.7 16.8 2 PMID:24443527 -6.2.1.44 acrylate candidatus pelagibacter communis 22.3 22.3 1 PMID:24443527 -6.2.1.44 acrylate ruegeria pomeroyi 14.3 7.65 2 PMID:24443527 -6.2.1.44 butyrate candidatus pelagibacter communis 43.8 43.8 1 PMID:24443527 -6.2.1.44 butyrate ruegeria pomeroyi 14.4 10.8 2 PMID:24443527 -6.2.1.44 propionate candidatus pelagibacter communis 17.7 17.7 1 PMID:24443527 -6.2.1.44 propionate ruegeria pomeroyi 10.8 7.25 2 PMID:24443527 -6.2.1.45 atp homo sapiens 6.0 4.7 2 PMID:16595681 -6.2.1.45 ubiquitin homo sapiens 6.0 4.7 2 PMID:16595681 -6.2.1.45 ubiquitin carrier protein e2 homo sapiens 6.0 4.7 2 PMID:16595681 -6.2.1.46 l-allo-isoleucine pseudomonas syringae 0.0015 0.0015 1 PMID:14679222 -6.2.1.46 l-isoleucine pseudomonas syringae 0.012 0.012 1 PMID:14679222 -6.2.1.46 l-leucine pseudomonas syringae 0.03 0.03 1 PMID:14679222 -6.2.1.46 l-valine pseudomonas syringae 0.023 0.023 1 PMID:14679222 -6.2.1.5 3-sulfinopropionate advenella mimigardefordensis 0.2 0.2 2 PMID:24141127 -6.2.1.5 3-sulfinopropionate escherichia coli k-12 0.2 0.2 2 PMID:24141127 -6.2.1.5 acetate acetobacter aceti 280.0 280.0 1 PMID:18502856 -6.2.1.5 acetyl-coa acetobacter aceti 75.2 75.2 1 PMID:18502856 -6.2.1.5 adp thermococcus kodakarensis 22.0 22.0 1 PMID:17640871 -6.2.1.5 atp advenella mimigardefordensis 58.8 58.8 2 PMID:24141127 -6.2.1.5 atp alcanivorax borkumensis 3.6 3.6 2 PMID:24141127 -6.2.1.5 atp escherichia coli k-12 19.6 19.6 2 PMID:24141127 -6.2.1.5 atp thermococcus kodakarensis 23.0 23.0 1 PMID:17640871 -6.2.1.5 coa advenella mimigardefordensis 40.3 40.3 2 PMID:24141127 -6.2.1.5 coa alcanivorax borkumensis 1.6 1.6 2 PMID:24141127 -6.2.1.5 coa escherichia coli k-12 26.7 26.7 2 PMID:24141127 -6.2.1.5 coa thermococcus kodakarensis 25.0 25.0 1 PMID:17640871 -6.2.1.5 d-malate advenella mimigardefordensis 2.1 2.1 2 PMID:24141127 -6.2.1.5 d-malate alcanivorax borkumensis 1.7 1.7 2 PMID:24141127 -6.2.1.5 d-malate escherichia coli k-12 1.2 1.2 2 PMID:24141127 -6.2.1.5 itaconate advenella mimigardefordensis 5.3 5.3 2 PMID:24141127 -6.2.1.5 itaconate alcanivorax borkumensis 0.5 0.5 2 PMID:24141127 -6.2.1.5 itaconate escherichia coli k-12 1.5 1.5 2 PMID:24141127 -6.2.1.5 l-malate advenella mimigardefordensis 2.6 2.6 2 PMID:24141127 -6.2.1.5 l-malate alcanivorax borkumensis 1.1 1.1 2 PMID:24141127 -6.2.1.5 l-malate escherichia coli k-12 1.8 1.8 2 PMID:24141127 -6.2.1.5 phosphate thermococcus kodakarensis 20.0 20.0 1 PMID:17640871 -6.2.1.5 succinate acetobacter aceti 70.9 70.9 1 PMID:18502856 -6.2.1.5 succinate advenella mimigardefordensis 31.1 31.1 2 PMID:24141127 -6.2.1.5 succinate alcanivorax borkumensis 2.7 2.7 2 PMID:24141127 -6.2.1.5 succinate escherichia coli 44.73 44.73 1 PMID:17642514 -6.2.1.5 succinate escherichia coli k-12 14.3 14.3 2 PMID:24141127 -6.2.1.5 succinate thermococcus kodakarensis 29.0 29.0 1 PMID:17640871 -6.2.1.5 succinyl-coa acetobacter aceti 201.0 201.0 1 PMID:18502856 -6.2.1.52 atp zophobas atratus 0.0015 0.0015 1 PMID:720526507 -6.2.1.52 ketoprofen aquatica lateralis 0.11 0.11 1 PMID:17617223 -6.2.1.52 l-firefly luciferin zophobas atratus 0.0015 0.0015 1 PMID:720526507 -6.2.1.53 l-proline pseudomonas fluorescens 5.5 5.5 1 PMID:11880032 -6.2.1.53 l-proline streptomyces coelicolor 2.8 2.8 1 PMID:11880032 -6.2.1.54 atp bacillus cereus 0.24 0.22749999999999998 2 PMID:19324056;PMID:25285205 -6.2.1.54 d-ala bacillus cereus 0.025 0.025 1 PMID:18847223 -6.2.1.54 d-alanine bacillus cereus 0.18 0.18 3 PMID:25285205 -6.2.1.54 d-alanine staphylococcus aureus 0.0057 0.0057 1 PMID:35362466 -6.2.1.54 l-ala bacillus cereus 0.11 0.11 1 PMID:18847223 -6.2.1.54 l-alanine bacillus cereus 0.32 0.32 3 PMID:25285205 -6.2.1.54 l-alanine staphylococcus aureus 0.013 0.013 1 PMID:35362466 -6.2.1.57 laurate mycobacterium tuberculosis 0.00239 0.00239 1 PMID:36896429 -6.2.1.57 palmitate mycobacterium tuberculosis 0.000654 0.000654 1 PMID:36896429 -6.2.1.60 pseudomonic acid c pseudoalteromonas sp. sank 73390 3.2 3.2 1 PMID:25726835 -6.2.1.62 3,4-dihydroxybenzoate bacillus anthracis 0.118 0.118 1 PMID:17346033 -6.2.1.62 atp bacillus anthracis 0.152 0.152 1 PMID:17346033 -6.2.1.64 atp homo sapiens 3.5 1.9449999999999998 4 PMID:19602421;PMID:22069333 -6.2.1.64 diphosphate homo sapiens 0.54 0.54 1 PMID:19602421 -6.2.1.69 l-cysteine pseudomonas aeruginosa 6.9 3.765 2 PMID:10555976 -6.2.1.70 l-serine pseudomonas syringae pv. syringae 0.02 0.02 1 PMID:16002467 -6.2.1.70 l-threonine pseudomonas syringae pv. syringae 0.485 0.485 1 PMID:16002467 -6.2.1.71 2,3,4-trihydroxybenzoate escherichia coli 0.45 0.45 1 PMID:2531000 -6.2.1.71 2,3-dihydroxybenzoate escherichia coli 5.5 2.8 3 PMID:20359185;PMID:2531000;PMID:31894971 -6.2.1.71 2,3-dihydroxybenzoate vibrio cholerae 2.3 2.3 1 PMID:11112537 -6.2.1.71 2,4-dihydroxybenzoate escherichia coli 3.23 3.23 1 PMID:2531000 -6.2.1.71 2,5-dihydroxybenzoic acid escherichia coli 3.15 3.15 1 PMID:2531000 -6.2.1.71 2-hydroxybenzoic acid escherichia coli 2.5 2.5 1 PMID:2531000 -6.2.1.71 3-hydroxybenzoate escherichia coli 0.3 0.3 1 PMID:20359185 -6.2.1.71 4-aminosalicylate escherichia coli 4.4 4.4 1 PMID:20359185 -6.2.1.71 [aryl-carrier protein entb] escherichia coli 2.8 2.8 1 PMID:20359185 -6.2.1.71 atp escherichia coli 5.83 4.3149999999999995 2 PMID:20359185;PMID:2531000 -6.2.1.71 holo-[aryl-carrier protein entb] escherichia coli 1.67 1.67 1 PMID:9214294 -6.2.1.71 salicylate escherichia coli 2.15 0.49150000000000005 4 PMID:1068898;PMID:20359185;PMID:31894971 -6.2.1.71 salicylate vibrio cholerae 0.49 0.49 1 PMID:11112537 -6.2.1.72 l-serine escherichia coli 0.0083 0.004985 2 PMID:1068898 -6.2.1.74 3-hydroxybenzoate amycolatopsis mediterranei 0.008 0.008 1 PMID:11955082 -6.2.1.74 benzoate amycolatopsis mediterranei 0.0018 0.0018 1 PMID:11955082 -6.2.1.75 (indol-3-yl)acetate aromatoleum aromaticum 4.3 4.3 1 PMID:27102732 -6.2.1.75 2-naphthyl acetate aromatoleum aromaticum 4.7 4.7 1 PMID:27102732 -6.2.1.75 phenyl acetate aromatoleum aromaticum 0.48 0.48 1 PMID:27102732 -6.2.1.76 atp rhizobium leguminosarum 20.0 11.35 2 PMID:10548546 -6.2.1.76 coa rhizobium leguminosarum 21.0 12.15 2 PMID:10548546 -6.2.1.76 malonate homo sapiens 0.413 0.413 1 PMID:21846720 -6.2.1.76 malonate rhizobium leguminosarum 19.0 19.0 1 PMID:10548546 -6.2.1.76 methylmalonate rhizobium leguminosarum 2.7 2.7 1 PMID:10548546 -6.2.1.8 oxalate lathyrus sativus 7.6 7.6 1 PMID:35359497 -6.2.2.1 ggrlgfygydlqd methanocaldococcus jannaschii 0.053 0.053 1 PMID:31139720 -6.2.2.2 atp uncultured prochloron sp. 06037a 0.043 0.043 1 PMID:20540059 -6.3.1.11 putrescine escherichia coli k-12 5.94 5.94 1 PMID:18495664 -6.3.1.13 1-o-(2-amino-2-deoxy-alpha-d-glucopyranosyl)-1d-myo-inositol mycolicibacterium smegmatis 3.15 3.15 1 PMID:17848100 -6.3.1.15 3-dimethylallyl-4-hydroxybenzoate streptomyces niveus 0.47 0.47 1 PMID:15218104 -6.3.1.15 4-hydroxy-3-methylbenzoate streptomyces niveus 0.36 0.36 1 PMID:15218104 -6.3.1.17 l-glutamate mus musculus 1.5 1.5 1 PMID:20657015 -6.3.1.19 [ider]-l-lysine mycolicibacterium smegmatis 0.014 0.014 1 PMID:26277445 -6.3.1.19 [prokaryotic ubiquitin-like protein]-l-glutamate mycobacterium tuberculosis 0.0023 0.0023 1 PMID:23471967 -6.3.1.19 [protein panb]-l-lysine mycobacterium tuberculosis 0.023 0.023 1 PMID:23471967 -6.3.1.2 adp exiguobacterium sp. 1.05 1.05 1 PMID:28175947 -6.3.1.2 adp providencia vermicola 9.14 9.14 1 PMID:30353099 -6.3.1.2 atp camellia sinensis 11.6 11.6 1 PMID:19921413 -6.3.1.2 atp escherichia coli 121.7 63.85 2 PMID:15797252;PMID:29039929 -6.3.1.2 atp homo sapiens 43.3 43.3 1 PMID:29039929 -6.3.1.2 atp pyrococcus sp. 52.7 52.7 1 PMID:9172372 -6.3.1.2 atp staphylococcus aureus 12.0 12.0 1 PMID:29039929 -6.3.1.2 atp trypanosoma cruzi 396.0 377.5 2 PMID:29320490 -6.3.1.2 hydroxylamine providencia vermicola 17.0 17.0 1 PMID:30353099 -6.3.1.2 hydroxylamine pyrococcus sp. 12.83 12.83 1 PMID:9172372 -6.3.1.2 l-glu arabidopsis thaliana 7.02 5.6 2 PMID:16338958 -6.3.1.2 l-glutamate camellia sinensis 15.2 15.2 1 PMID:19921413 -6.3.1.2 l-glutamate drosophila melanogaster 0.0307 0.0307 1 PMID:33327463 -6.3.1.2 l-glutamate escherichia coli 131.7 131.7 1 PMID:29039929 -6.3.1.2 l-glutamate homo sapiens 85.0 85.0 1 PMID:29039929 -6.3.1.2 l-glutamate pyrococcus sp. 36.5 36.5 1 PMID:9172372 -6.3.1.2 l-glutamate staphylococcus aureus 23.3 23.3 1 PMID:29039929 -6.3.1.2 l-glutamate trichormus azollae 42.0 42.0 1 PMID:10583418 -6.3.1.2 l-glutamate trypanosoma cruzi 392.0 374.5 2 PMID:29320490 -6.3.1.2 l-glutamine exiguobacterium sp. 1.62 1.62 1 PMID:28175947 -6.3.1.2 l-glutamine providencia vermicola 30.5 30.5 1 PMID:30353099 -6.3.1.2 nh3 drosophila melanogaster 0.0153 0.0153 1 PMID:33327463 -6.3.1.2 nh4+ arabidopsis thaliana 7.1 5.029999999999999 2 PMID:16338958 -6.3.1.2 nh4+ camellia sinensis 13.5 13.5 1 PMID:19921413 -6.3.1.2 nh4+ trypanosoma cruzi 535.0 507.5 2 PMID:29320490 -6.3.1.20 apoh-protein escherichia coli 0.258 0.258 1 PMID:16043486 -6.3.1.20 atp escherichia coli 0.133 0.133 1 PMID:16043486 -6.3.1.20 lpla acceptor peptide 2 escherichia coli 0.22 0.22 1 PMID:19863063 -6.3.1.20 octanoic acid escherichia coli 0.04 0.04 1 PMID:19684135 -6.3.1.20 octanoyl-[coa] escherichia coli 0.0037 0.0037 1 PMID:35764173 -6.3.1.20 r-lipoic acid escherichia coli 0.219 0.219 1 PMID:16043486 -6.3.1.21 formate escherichia coli 37.6 37.6 1 PMID:8117714 -6.3.1.5 atp homo sapiens 18.5 11.145 2 PMID:31911602 -6.3.1.5 deamido-nad+ francisella tularensis 0.25 0.25 1 PMID:19204287 -6.3.1.5 deamido-nad+ homo sapiens 23.4 13.299999999999999 2 PMID:31911602 -6.3.1.5 deamido-nad+ methanocaldococcus jannaschii 0.2 0.2 1 PMID:22720044 -6.3.1.5 deamido-nmn francisella tularensis 0.5 0.5 1 PMID:19204287 -6.3.1.5 l-glutamine azospirillum brasilense 0.23 0.135 2 PMID:29581233 -6.3.1.5 l-glutamine herbaspirillum seropedicae 0.09 0.09 1 PMID:29581233 -6.3.1.5 l-glutamine homo sapiens 3.72 3.72 1 PMID:31911602 -6.3.1.5 nh3 homo sapiens 20.0 20.0 1 PMID:31911602 -6.3.1.5 nh4+ azospirillum brasilense 0.23 0.14500000000000002 2 PMID:29581233 -6.3.1.5 nh4+ herbaspirillum seropedicae 0.07 0.07 1 PMID:29581233 -6.3.1.6 ethylamine escherichia coli 1037.48 1037.48 1 PMID:32103318 -6.3.1.6 l-cysteine escherichia coli 3895.58 3895.58 1 PMID:32103318 -6.3.1.8 gamma-glu-l-cys(s-butyl)-gly crithidia fasciculata 9.2 9.2 1 PMID:9041518 -6.3.1.8 gamma-glu-l-cys(s-ethyl)-gly crithidia fasciculata 11.3 11.3 1 PMID:9041518 -6.3.1.8 gamma-glu-l-cys(s-propyl)-gly crithidia fasciculata 8.7 8.7 1 PMID:9041518 -6.3.1.8 gamma-l-glu-l-ala-gly crithidia fasciculata 2.5 2.5 1 PMID:9041518 -6.3.1.8 gamma-l-glu-l-cys(s-methyl)-gly crithidia fasciculata 8.8 8.8 1 PMID:9041518 -6.3.1.8 gamma-l-glu-l-cys-gly crithidia fasciculata 15.0 15.0 1 PMID:9041518 -6.3.1.8 gamma-l-glu-l-ile-gly crithidia fasciculata 10.0 10.0 1 PMID:9041518 -6.3.1.8 gamma-l-glu-l-val-gly crithidia fasciculata 11.8 11.8 1 PMID:9041518 -6.3.1.8 spermidine crithidia fasciculata 4.2 4.2 1 PMID:15537651 -6.3.1.9 glutathione leishmania donovani 1.3 1.3 1 PMID:22050226 -6.3.1.9 glutathione leishmania major 2.0 2.0 1 PMID:15610825 -6.3.1.9 glutathione trypanosoma brucei 5.2 2.45 4 PMID:23814051 -6.3.1.9 glutathionylspermidine crithidia fasciculata 8.7 8.7 1 PMID:15537651 -6.3.1.9 n1-(gamma-l-glutamyl-l-cysteinyl-glycyl)-spermidine trypanosoma cruzi 2.8 2.8 1 PMID:12121990 -6.3.1.9 n1-glutathionylspermidine crithidia fasciculata 10.0 10.0 1 PMID:2354163 -6.3.1.9 n8-glutathionylspermidine crithidia fasciculata 24.3 24.3 1 PMID:2354163 -6.3.1.9 spermidine crithidia fasciculata 28.6 28.6 1 PMID:2354163 -6.3.2.1 (r)-pantoate arabidopsis thaliana 0.039 0.039 1 PMID:17040917 -6.3.2.1 (r)-pantoate bacillus subtilis 42.2 42.2 1 PMID:29737393 -6.3.2.1 (r)-pantoate bacillus thuringiensis 35.9 35.9 1 PMID:29737393 -6.3.2.1 (r)-pantoate corynebacterium glutamicum 127.6 127.6 1 PMID:29737393 -6.3.2.1 (r)-pantoate escherichia coli 59.1 30.25 2 PMID:16990935;PMID:29737393 -6.3.2.1 (r)-pantoate lotus japonicus 6.08 3.35 2 * -6.3.2.1 (r)-pantoate mycobacterium tuberculosis 2.94 2.34 2 PMID:12717031 -6.3.2.1 (r)-pantoate staphylococcus aureus 1.5 1.5 1 PMID:20568730 -6.3.2.1 atp escherichia coli 1.4 1.4 1 PMID:16990935 -6.3.2.1 beta-alanine arabidopsis thaliana 0.16 0.16 1 PMID:17040917 -6.3.2.1 beta-alanine bacillus subtilis 42.2 42.2 1 PMID:29737393 -6.3.2.1 beta-alanine bacillus thuringiensis 35.9 35.9 1 PMID:29737393 -6.3.2.1 beta-alanine corynebacterium glutamicum 127.6 127.6 1 PMID:29737393 -6.3.2.1 beta-alanine escherichia coli 59.1 30.25 2 PMID:16990935;PMID:29737393 -6.3.2.1 beta-alanine mycobacterium tuberculosis 3.4 2.205 2 PMID:11669627;PMID:15170354 -6.3.2.1 beta-alanine staphylococcus aureus 1.5 1.5 1 PMID:20568730 -6.3.2.1 d-pantoate mycobacterium tuberculosis 3.4 3.4 1 PMID:11669627 -6.3.2.13 atp erysipelothrix rhusiopathiae 1.83 1.83 1 PMID:26700151 -6.3.2.13 atp mycobacterium tuberculosis 1.3 1.3 1 PMID:21153518 -6.3.2.13 l-alanine erysipelothrix rhusiopathiae 2.83 2.83 1 PMID:26700151 -6.3.2.13 meso-2,6-diaminoheptanedioate erysipelothrix rhusiopathiae 4.17 4.17 1 PMID:26700151 -6.3.2.13 udp-n-acetyl-alpha-d-muramoyl-glycyl-d-glutamate erysipelothrix rhusiopathiae 8.83 8.83 1 PMID:26700151 -6.3.2.13 udp-n-acetyl-alpha-d-muramoyl-l-alanyl-d-glutamate erysipelothrix rhusiopathiae 3.33 3.33 1 PMID:26700151 -6.3.2.13 udp-n-acetyl-alpha-d-muramoyl-l-seryl-d-glutamate erysipelothrix rhusiopathiae 3.67 3.67 1 PMID:26700151 -6.3.2.14 2,3-dihydroxybenzoate escherichia coli 2.8 2.8 1 PMID:20359185 -6.3.2.14 3-hydroxybenzoate escherichia coli 0.3 0.3 1 PMID:20359185 -6.3.2.14 4-aminosalicylic acid escherichia coli 4.4 4.4 1 PMID:20359185 -6.3.2.14 atp escherichia coli 2.8 2.8 1 PMID:20359185 -6.3.2.14 l-ser escherichia coli 12.7 12.7 1 PMID:1338974 -6.3.2.14 phosphopantetheinylated entb escherichia coli 2.8 2.8 1 PMID:20359185 -6.3.2.14 salicylic acid escherichia coli 0.8 0.8 1 PMID:20359185 -6.3.2.17 (6r)-10-formyl-5,6,7,8-tetrahydropteroylglutamate mus musculus 0.212 0.1535 2 PMID:11772020 -6.3.2.17 (6s)-5,6,7,8-tetrahydropteroylglutamate mus musculus 0.215 0.1655 2 PMID:11772020 -6.3.2.17 (6s)-5-formyl-5,6,7,8-tetrahydropteroylglutamate mus musculus 0.115 0.094 2 PMID:11772020 -6.3.2.17 5,10-dideazatetrahydrofolic acid mus musculus 0.145 0.0775 2 PMID:11772020 -6.3.2.17 5,6,7,8-tetrahydropteroyl-glu homo sapiens 0.99 0.99 1 PMID:9250977 -6.3.2.17 5,6,7,8-tetrahydropteroyl-glu2 homo sapiens 0.81 0.81 1 PMID:9250977 -6.3.2.17 5-methyl-5,6,7,8-tetrahydropteroylglutamate mus musculus 0.22 0.165 2 PMID:11772020 -6.3.2.17 7,8-dihydropteroyl-glu homo sapiens 0.84 0.84 1 PMID:9250977 -6.3.2.17 7,8-dihydropteroyl-glu2 homo sapiens 0.95 0.95 1 PMID:9250977 -6.3.2.17 aminopterin homo sapiens 1.17 1.17 1 PMID:9250977 -6.3.2.17 aminopterin mus musculus 0.22 0.1925 2 PMID:11772020 -6.3.2.17 aminopterin sus scrofa 2.0 2.0 1 PMID:3828321 -6.3.2.17 l-glu sus scrofa 1.7 1.7 1 PMID:3828321 -6.3.2.17 pteroyl-glu homo sapiens 0.65 0.65 1 PMID:9250977 -6.3.2.17 pteroyl-glu2 homo sapiens 0.82 0.82 1 PMID:9250977 -6.3.2.17 pteroyl-glu3 homo sapiens 0.55 0.55 1 PMID:9250977 -6.3.2.17 pteroyl-glu4 homo sapiens 0.34 0.34 1 PMID:9250977 -6.3.2.17 pteroyl-glu5 homo sapiens 0.01 0.01 1 PMID:9250977 -6.3.2.2 1-aminobutyrate myxococcus xanthus 1.42 1.42 1 PMID:35277888 -6.3.2.2 4-aminobutyrate trypanosoma brucei 0.14 0.14 1 PMID:11851421 -6.3.2.2 atp arabidopsis thaliana 6.8 6.8 1 PMID:17766407 -6.3.2.2 atp escherichia coli 46.9 37.8 2 PMID:23126248 -6.3.2.2 atp mus musculus 8.2 5.05 2 PMID:15596139 -6.3.2.2 atp myxococcus xanthus 2.01 2.01 1 PMID:35277888 -6.3.2.2 atp pasteurella multocida 22.4 22.4 2 PMID:16339152 -6.3.2.2 atp synechocystis sp. 0.137 0.137 1 PMID:23170977 -6.3.2.2 atp trypanosoma brucei 3.8 3.0999999999999996 2 PMID:11527962 -6.3.2.2 l-cys arabidopsis thaliana 4.5 4.5 1 PMID:17766407 -6.3.2.2 l-cys pasteurella multocida 25.3 25.3 1 PMID:16339152 -6.3.2.2 l-cysteine agrobacterium tumefaciens 7920.0 7920.0 1 PMID:18346196 -6.3.2.2 l-cysteine brassica juncea 10190.0 10190.0 1 PMID:18346196 -6.3.2.2 l-cysteine escherichia coli 46.6 35.4 2 PMID:23126248 -6.3.2.2 l-cysteine mus musculus 8.2 5.05 2 PMID:15596139 -6.3.2.2 l-cysteine myxococcus xanthus 1.11 1.11 1 PMID:35277888 -6.3.2.2 l-cysteine pasteurella multocida 25.3 25.3 1 PMID:16339152 -6.3.2.2 l-cysteine synechocystis sp. 0.42 0.42 1 PMID:23170977 -6.3.2.2 l-cysteine xanthomonas campestris 7350.0 7350.0 1 PMID:18346196 -6.3.2.2 l-glu arabidopsis thaliana 6.1 6.1 1 PMID:17766407 -6.3.2.2 l-glu pasteurella multocida 24.3 24.3 1 PMID:16339152 -6.3.2.2 l-glutamate agrobacterium tumefaciens 7920.0 7920.0 1 PMID:18346196 -6.3.2.2 l-glutamate brassica juncea 10190.0 10190.0 1 PMID:18346196 -6.3.2.2 l-glutamate escherichia coli 31.4 26.75 2 PMID:23126248 -6.3.2.2 l-glutamate mus musculus 8.2 5.05 2 PMID:15596139 -6.3.2.2 l-glutamate myxococcus xanthus 0.67 0.67 1 PMID:35277888 -6.3.2.2 l-glutamate pasteurella multocida 24.3 24.3 1 PMID:16339152 -6.3.2.2 l-glutamate synechocystis sp. 0.35 0.35 1 PMID:23170977 -6.3.2.2 l-glutamate trypanosoma brucei 3.9 3.9 1 PMID:11851421 -6.3.2.2 l-glutamate xanthomonas campestris 7350.0 7350.0 1 PMID:18346196 -6.3.2.2 mg2+ trypanosoma brucei 3.8 3.8 1 PMID:11527962 -6.3.2.2 mn2+ trypanosoma brucei 2.5 2.5 1 PMID:11527962 -6.3.2.26 atp hapsidospora chrysogena 0.0833 0.0833 1 PMID:9558329 -6.3.2.26 cysteine hapsidospora chrysogena 0.133 0.133 1 PMID:9558329 -6.3.2.3 atp arabidopsis thaliana 12.1 12.1 2 PMID:15302873;PMID:17452339 -6.3.2.3 atp myxococcus xanthus 3.77 3.77 1 PMID:35277888 -6.3.2.3 atp pasteurella multocida 55.0 40.25 2 PMID:16339152 -6.3.2.3 atp pseudoalteromonas haloplanktis 5.32 3.57 6 PMID:22777241 -6.3.2.3 atp rattus norvegicus 13.0 13.0 1 PMID:10964706 -6.3.2.3 atp synechocystis sp. 5.4 5.4 1 PMID:23170977 -6.3.2.3 gamma-glu-l-cys arabidopsis thaliana 12.2 12.2 2 PMID:15302873;PMID:17452339 -6.3.2.3 gamma-glu-l-cys pasteurella multocida 55.0 40.95 2 PMID:16339152 -6.3.2.3 gamma-l-glu-aminobutanoate homo sapiens 19.5 19.5 1 PMID:21683691 -6.3.2.3 gamma-l-glu-l-alpha-aminobutyrate rattus norvegicus 13.0 13.0 1 PMID:10964706 -6.3.2.3 gamma-l-glu-l-cys homo sapiens 6.5 6.5 1 PMID:14990577 -6.3.2.3 gamma-l-glutamyl-l-cysteine homo sapiens 15.68 1.955 4 PMID:21771585 -6.3.2.3 gamma-l-glutamyl-l-cysteine myxococcus xanthus 3.96 3.96 1 PMID:35277888 -6.3.2.3 gamma-l-glutamyl-l-cysteine synechocystis sp. 4.62 4.62 1 PMID:23170977 -6.3.2.3 gly arabidopsis thaliana 12.6 12.6 2 PMID:15302873;PMID:17452339 -6.3.2.3 gly homo sapiens 18.8 18.8 1 PMID:20800579 -6.3.2.3 gly pasteurella multocida 55.0 45.65 2 PMID:16339152 -6.3.2.3 glycine homo sapiens 15.68 1.955 4 PMID:21771585 -6.3.2.3 glycine myxococcus xanthus 3.04 3.04 1 PMID:35277888 -6.3.2.3 glycine rattus norvegicus 13.0 13.0 1 PMID:10964706 -6.3.2.3 glycine synechocystis sp. 4.22 4.22 1 PMID:23170977 -6.3.2.35 d-asparagine enterococcus casseliflavus 8.87 8.87 1 PMID:9294159 -6.3.2.35 d-serine enterococcus casseliflavus 8.17 8.17 1 PMID:9294159 -6.3.2.4 atp helicobacter pylori 1.9 1.9 1 PMID:18320587 -6.3.2.4 atp mycobacterium tuberculosis 6.38 3.190365 2 PMID:29401644;PMID:32010089 -6.3.2.4 d-ala escherichia coli 17.0 7.4 3 PMID:1993184;PMID:1998664 -6.3.2.4 d-alanine acinetobacter baumannii 30.08 30.08 1 PMID:26502962 -6.3.2.4 d-alanine chlamydia trachomatis 48.5 48.5 1 PMID:15948948 -6.3.2.4 d-alanine escherichia coli 31.2 20.7 4 PMID:8756703;PMID:9545431 -6.3.2.4 d-alanine helicobacter pylori 1.9 1.9 1 PMID:18320587 -6.3.2.4 d-alanine mycobacterium tuberculosis 9.48 4.740365000000001 2 PMID:29401644;PMID:32010089 -6.3.2.4 d-alanine streptomyces lavendulae 1.67 1.67 1 PMID:15302885 -6.3.2.4 d-alanine thermus thermophilus 1.48 1.165 4 PMID:32335509 -6.3.2.4 d-serine escherichia coli 2.6 2.6 1 PMID:9545431 -6.3.2.41 n-acetyl-l-aspartate mus musculus 3.0 2.6 3 PMID:20657015 -6.3.2.43 [lysw]-c-terminal-l-glutamate54 thermus thermophilus 2.0 2.0 1 PMID:19620981 -6.3.2.43 atp thermus thermophilus 5.2 5.2 1 PMID:19620981 -6.3.2.43 l-2-aminoadipate thermus thermophilus 0.85 0.85 1 PMID:19620981 -6.3.2.45 atp escherichia coli 4.83 4.83 1 PMID:17384195 -6.3.2.45 l-ala-d-glu escherichia coli 1.0 1.0 1 PMID:17384195 -6.3.2.45 l-ala-gamma-d-glu-l-lys escherichia coli 0.27 0.27 1 PMID:17384195 -6.3.2.45 l-ala-gamma-d-glu-l-lys-d-ala escherichia coli 0.32 0.32 1 PMID:17384195 -6.3.2.45 l-alanyl-gamma-d-glutamyl-meso-2,6-diaminoheptanedioate escherichia coli 4.83 4.83 1 PMID:17384195 -6.3.2.45 l-alanyl-gamma-d-glutamyl-meso-2,6-diaminoheptanedioyl-d-alanine escherichia coli 3.17 3.17 1 PMID:17384195 -6.3.2.45 l-alanyl-gamma-d-glutamyl-meso-2,6-diaminoheptanedioyl-d-alanyl-d-alanine escherichia coli 2.83 2.83 1 PMID:17384195 -6.3.2.45 udp-n-alpha-d-acetylmuramate escherichia coli 4.83 4.83 1 PMID:17384195 -6.3.2.46 fumarate pantoea agglomerans 11.6 11.6 1 PMID:19807062 -6.3.2.46 succinate pantoea agglomerans 3.8 3.8 1 PMID:19807062 -6.3.2.47 3-((((2r,3r)-3-carboxyoxiran-2-yl)carbonyl)amino)-l-alanine pantoea agglomerans 3.0 3.0 1 PMID:20945916 -6.3.2.47 3-[[(2e)-4-amino-4-oxobut-2-enoyl]amino]-l-alanine pantoea agglomerans 0.3 0.3 1 PMID:20945916 -6.3.2.49 l-alanine bacillus subtilis 9.7 8.7 2 PMID:22407814 -6.3.2.49 l-phenylalanine bacillus subtilis 9.7 8.7 2 PMID:22407814 -6.3.2.5 (r)-4'-phosphopantothenate escherichia coli 0.88 0.88 1 PMID:11278255 -6.3.2.5 atp homo sapiens 0.56 0.56 1 PMID:19683078 -6.3.2.5 ctp enterococcus faecalis 2.9 2.9 1 PMID:19182993 -6.3.2.5 ctp homo sapiens 0.53 0.53 1 PMID:19683078 -6.3.2.5 n-[(r)-4'-phosphopantothenoyl]-l-cysteine escherichia coli 0.83 0.83 1 PMID:11278255 -6.3.2.51 (r)-4'-phosphopantothenate enterococcus faecalis 2.9 2.9 1 PMID:19182993 -6.3.2.51 (r)-4'-phosphopantothenate homo sapiens 0.56 0.545 2 PMID:19683078 -6.3.2.51 ctp enterococcus faecalis 2.9 2.9 1 PMID:19182993 -6.3.2.51 l-cysteine enterococcus faecalis 2.9 2.9 1 PMID:19182993 -6.3.2.54 citrate staphylococcus aureus 0.268 0.268 1 PMID:19775248 -6.3.2.61 [modified porcine brain tubulin]-l-glutamate mus musculus 0.0032 0.0032 1 PMID:32747782 -6.3.2.61 [unmodified human tubulin]-l-glutamate mus musculus 0.0037 0.0037 1 PMID:32747782 -6.3.2.65 udp-2-acetamido-4-amino-2,4,6-trideoxy-alpha-d-galactose bacillus cereus 0.0245 0.0245 1 PMID:25368324 -6.3.2.7 atp streptococcus pyogenes 9.0 9.0 1 * -6.3.2.7 l-lys streptococcus pyogenes 9.0 9.0 1 * -6.3.2.7 l-lysine staphylococcus aureus 4.833 4.833 1 PMID:24064214 -6.3.2.7 udp-n-acetylmuramoyl-l-ala-d-glu streptococcus pyogenes 9.0 9.0 1 * -6.3.2.8 2-amino-benzylpropionate escherichia coli 13.5 13.5 1 PMID:8976565 -6.3.2.8 2-amino-ethylpropionate escherichia coli 15.2 15.2 1 PMID:8976565 -6.3.2.8 2-amino-methylpropionate escherichia coli 28.3 28.3 1 PMID:8976565 -6.3.2.8 2-amino-n-butyric acid escherichia coli 25.0 25.0 1 PMID:8976565 -6.3.2.8 2-amino-n-hydroxymethylpropionamide escherichia coli 11.7 11.7 1 PMID:8976565 -6.3.2.8 2-amino-propionamide escherichia coli 18.3 18.3 1 PMID:8976565 -6.3.2.8 2-amino-tert-butylpropionate escherichia coli 21.7 21.7 1 PMID:8976565 -6.3.2.8 beta-alanine escherichia coli 2.5 2.5 1 PMID:8976565 -6.3.2.8 beta-chloro-ala escherichia coli 20.0 20.0 1 PMID:8976565 -6.3.2.8 beta-chloro-l-ala escherichia coli 11.1 11.1 1 PMID:8550531 -6.3.2.8 beta-cyano-l-ala escherichia coli 26.7 26.7 1 PMID:8976565 -6.3.2.8 dl-propargylglycine escherichia coli 20.0 20.0 1 PMID:8976565 -6.3.2.8 gly escherichia coli 21.7 16.7 2 PMID:8550531;PMID:8976565 -6.3.2.8 glycine mycobacterium tuberculosis 1.53 1.53 1 PMID:23555903 -6.3.2.8 l-ala escherichia coli 16.3 11.575 2 PMID:8550531;PMID:8976565 -6.3.2.8 l-alanine mycobacterium tuberculosis 1.0 1.0 1 PMID:23555903 -6.3.2.8 l-cys escherichia coli 20.0 20.0 1 PMID:8976565 -6.3.2.8 l-ile escherichia coli 5.17 5.17 1 PMID:8976565 -6.3.2.8 l-ser escherichia coli 25.0 18.2 2 PMID:8550531;PMID:8976565 -6.3.2.8 l-serine mycobacterium tuberculosis 1.2 1.2 1 PMID:23555903 -6.3.2.8 l-thr escherichia coli 23.3 23.3 1 PMID:8976565 -6.3.2.8 l-val escherichia coli 21.7 21.7 1 PMID:8976565 -6.3.2.8 l-vinylglycine escherichia coli 15.3 15.3 1 PMID:8976565 -6.3.2.8 n-(2-aminopropionyl)piperidine escherichia coli 6.17 6.17 1 PMID:8976565 -6.3.3.2 (6s)-5-formyltetrahydrofolate mus musculus 16.3 16.3 1 PMID:15135403 -6.3.3.2 5-formyltetrahydrofolate arabidopsis thaliana 5.3 5.3 1 PMID:12207015 -6.3.3.2 5-formyltetrahydrofolate mus musculus 3.33 3.33 1 PMID:17250800 -6.3.3.2 5-formyltetrahydrofolate mycoplasmoides pneumoniae 1.0 0.94 3 PMID:16104022;PMID:18473156;PMID:22773193 -6.3.3.2 atp mycoplasmoides pneumoniae 1.0 1.0 3 PMID:16104022;PMID:18473156;PMID:31401777 -6.3.3.3 (7r,8s)-7,8-diaminopelargonic acid escherichia coli 49.0 49.0 1 PMID:25801336 -6.3.3.3 (7r,8s)-7,8-diaminopelargonic acid mycobacterium tuberculosis 13.3 13.3 1 PMID:25801336 -6.3.3.3 atp escherichia coli 38.6 38.6 1 PMID:25801336 -6.3.3.3 atp mycobacterium tuberculosis 11.7 11.7 1 PMID:25801336 -6.3.3.3 ctp escherichia coli 28.1 28.1 1 PMID:25801336 -6.3.3.3 ctp mycobacterium tuberculosis 15.2 15.2 1 PMID:25801336 -6.3.3.3 gtp escherichia coli 29.0 29.0 1 PMID:25801336 -6.3.3.3 gtp mycobacterium tuberculosis 11.1 11.1 1 PMID:25801336 -6.3.3.3 itp mycobacterium tuberculosis 10.2 10.2 1 PMID:25801336 -6.3.3.3 nahco3 escherichia coli 38.4 38.4 1 PMID:25801336 -6.3.3.3 nahco3 mycobacterium tuberculosis 9.9 9.9 1 PMID:25801336 -6.3.3.3 ttp mycobacterium tuberculosis 11.8 11.8 1 PMID:25801336 -6.3.3.3 utp mycobacterium tuberculosis 11.4 11.4 1 PMID:25801336 -6.3.3.4 (2'r)-methyl-l-n2-(2-carboxyethyl)arginine streptomyces clavuligerus 0.032 0.032 1 PMID:23616913 -6.3.3.4 (2's)-ethyl-l-n2-(2-carboxyethyl)arginine streptomyces clavuligerus 0.0023 0.0023 1 PMID:23616913 -6.3.3.4 (2's)-methyl-l-n2-(2-carboxyethyl)arginine streptomyces clavuligerus 0.023 0.023 1 PMID:23616913 -6.3.3.4 l-n2-(2-carboxyethyl)arginine streptomyces clavuligerus 0.87 0.87 1 PMID:23616913 -6.3.3.5 d-homocysteine streptomyces lavendulae 860.0 860.0 1 PMID:23529730 -6.3.3.5 o-ureido-d-serine streptomyces lavendulae 2200.0 2200.0 1 PMID:23529730 -6.3.3.6 (2r,5r)-5-carboxymethylproline pectobacterium carotovorum 0.122 0.122 1 PMID:12820893 -6.3.3.6 (2s,5r)-5-carboxymethylproline pectobacterium carotovorum 0.2 0.2 1 PMID:12820893 -6.3.3.6 (2s,5s)-5-carboxymethylproline pectobacterium carotovorum 0.36 0.36 3 PMID:12820893;PMID:17658887;PMID:19371088 -6.3.3.6 atp pectobacterium carotovorum 0.28 0.28 1 PMID:12820893 -6.3.4.12 ammonium chloride rhodovulum sp. 12e13 4.26 4.26 1 PMID:33199371 -6.3.4.12 ethylamine rhodovulum sp. 12e13 4.09 4.09 1 PMID:33199371 -6.3.4.12 hydroxylamine rhodovulum sp. 12e13 4.15 4.15 1 PMID:33199371 -6.3.4.12 methylamine rhodovulum sp. 12e13 4.18 4.18 1 PMID:33199371 -6.3.4.12 propylamine rhodovulum sp. 12e13 4.23 4.23 1 PMID:33199371 -6.3.4.13 5'-phosphoribosylglycinamide gallus gallus 2.3 2.3 1 PMID:8626510 -6.3.4.13 beta-ala gallus gallus 4.8 4.8 1 PMID:8626510 -6.3.4.13 gly gallus gallus 7.0 7.0 1 PMID:8626510 -6.3.4.13 sarcosine gallus gallus 3.6 3.6 1 PMID:8626510 -6.3.4.14 atp escherichia coli 1.23 0.294 4 PMID:10747803;PMID:16793549;PMID:21592965 -6.3.4.14 biotin escherichia coli 1.05 0.815 2 PMID:10542197;PMID:19213731 -6.3.4.14 biotin-carboxyl-carrier protein escherichia coli 16.68 16.68 1 PMID:10542197 -6.3.4.14 hco3- escherichia coli 0.44 0.32 5 PMID:19213731;PMID:21592965 -6.3.4.15 [escherichia coli apo-biotin-carboxyl-carrier-protein mutant m136s]-l-lysine escherichia coli 0.58 0.58 1 PMID:16480719 -6.3.4.15 [escherichia coli apo-biotin-carboxyl-carrier-protein]-l-lysine escherichia coli 0.165 0.165 1 PMID:16480719 -6.3.4.15 [sulfolobus tokodaii apo-biotin-carboxyl-carrier-protein mutant s136m]-lysine sulfurisphaera tokodaii 0.165 0.08735000000000001 2 PMID:16480719;PMID:16616010 -6.3.4.15 [sulfolobus tokodaii apo-biotin-carboxyl-carrier-protein]-lysine sulfurisphaera tokodaii 0.004 0.004 1 PMID:16480719;PMID:16616010 -6.3.4.15 atp escherichia coli 0.48 0.325 2 PMID:11714929;PMID:24375025 -6.3.4.15 atp mycobacterium tuberculosis 0.017 0.017 1 PMID:24723382 -6.3.4.15 atp staphylococcus aureus 360000.0 360000.0 1 PMID:22437830 -6.3.4.15 biotin escherichia coli 0.44 0.37 2 PMID:11714929;PMID:24375025 -6.3.4.15 biotin staphylococcus aureus 450000.0 450000.0 1 PMID:22437830 -6.3.4.15 desthiobiotin escherichia coli 0.29 0.29 1 PMID:24375025 -6.3.4.15 yeast acceptor peptide saccharomyces cerevisiae 0.0017 0.0017 1 PMID:17472384 -6.3.4.16 atp methanobrevibacter smithii 0.043 0.043 1 PMID:23107800 -6.3.4.16 hco3- methanobrevibacter smithii 0.044 0.044 1 PMID:23107800 -6.3.4.16 nh3 homo sapiens 5.73 5.73 1 PMID:18679823 -6.3.4.16 nh4+ methanobrevibacter smithii 0.052 0.052 1 PMID:23107800 -6.3.4.18 5-amino-1-(5-phospho-d-ribosyl)imidazole staphylococcus aureus 24.83 24.83 1 PMID:21795812 -6.3.4.18 atp escherichia coli 5.9 5.9 1 PMID:19384989 -6.3.4.18 hco3- aspergillus clavatus 0.063 0.063 1 PMID:23899325 -6.3.4.19 [trnaile2]-cytidine34 escherichia coli 0.012 0.012 1 PMID:16039592 -6.3.4.19 atp escherichia coli 0.015 0.015 1 PMID:16039592 -6.3.4.19 l-lysine escherichia coli 0.07 0.07 1 PMID:16039592 -6.3.4.19 mature [trnaile2]-cytidine34 geobacillus kaustophilus 0.03 0.03 1 PMID:19847269 -6.3.4.19 precursor [trnaile2]-cytidine34 geobacillus kaustophilus 0.025 0.025 1 PMID:19847269 -6.3.4.2 2',3'-dialdehyde adenosine 5'-triphosphate escherichia coli 0.054 0.0299 2 PMID:16427816 -6.3.4.2 2'-deoxy-gtp escherichia coli 1.5 1.5 1 PMID:18003612 -6.3.4.2 6-thioguanosine 5'-triphosphate escherichia coli 8.5 8.5 1 PMID:18003612 -6.3.4.2 atp escherichia coli 12.8 10.8 3 PMID:16427816 -6.3.4.2 atp toxoplasma gondii 6.0 6.0 1 PMID:29623259 -6.3.4.2 gln escherichia coli 6.1 6.1 2 PMID:12383057;PMID:15511226 -6.3.4.2 gln lactococcus lactis 1.49 1.49 1 PMID:15019842 -6.3.4.2 gln-oh escherichia coli 0.453 0.453 1 PMID:15511226 -6.3.4.2 glutamine escherichia coli 8.1 6.1 5 PMID:11336655;PMID:16427816 -6.3.4.2 gtp escherichia coli 10.6 10.3 3 PMID:18003612 -6.3.4.2 guanosine 5'-tetraphosphate escherichia coli 4.0 4.0 1 PMID:18003612 -6.3.4.2 itp escherichia coli 5.2 5.2 1 PMID:18003612 -6.3.4.2 l-glutamine escherichia coli 6.0 3.705 2 PMID:15511226;PMID:30251661 -6.3.4.2 l-glutamine toxoplasma gondii 29.6 29.6 1 PMID:29623259 -6.3.4.2 nh2oh escherichia coli 14.0 14.0 1 PMID:15511226 -6.3.4.2 nh3 escherichia coli 11.3 9.5 5 PMID:12383057;PMID:15511226;PMID:16427816 -6.3.4.2 nh4+ lactococcus lactis 6.3 6.3 1 PMID:15670165 -6.3.4.2 nh4cl escherichia coli 9.5 9.5 1 PMID:30251661 -6.3.4.2 nh4oac escherichia coli 7.7 7.7 1 PMID:30251661 -6.3.4.2 o-methylguanosine 5'-triphosphate escherichia coli 2.8 2.8 1 PMID:18003612 -6.3.4.2 utp anoxybacillus gonensis 0.762 0.762 1 * -6.3.4.2 utp escherichia coli 14.0 10.3 4 PMID:16427816;PMID:18260824 -6.3.4.2 utp toxoplasma gondii 31.9 31.9 1 PMID:29623259 -6.3.4.21 5-phospho-alpha-d-ribose 1-diphosphate homo sapiens 0.36 0.185 2 PMID:21742010 -6.3.4.21 nicotinate homo sapiens 0.25 0.131 2 PMID:21742010 -6.3.4.22 [trnaile2]-cytidine34 archaeoglobus fulgidus 0.0065 0.0065 1 PMID:22002222 -6.3.4.22 agmatine archaeoglobus fulgidus 0.006 0.006 1 PMID:22002222 -6.3.4.22 atp archaeoglobus fulgidus 0.0062 0.0062 1 PMID:22002222 -6.3.4.24 atp methanocaldococcus fervens 5.9 5.9 1 PMID:25211225 -6.3.4.24 l-glutamate methanocaldococcus fervens 5.8 5.8 1 PMID:25211225 -6.3.4.24 tyramine methanocaldococcus fervens 4.8 4.8 1 PMID:25211225 -6.3.4.3 (6r,s)-tetrahydrofolate monoglutamate homo sapiens 16.0 16.0 1 PMID:16171773 -6.3.4.3 (6r,s)-tetrahydrofolate pteroylpentaglutamate homo sapiens 2.6 2.6 1 PMID:16171773 -6.3.4.3 (6r,s)-tetrahydrofolate pteroyltriglutamate homo sapiens 10.0 10.0 1 PMID:16171773 -6.3.4.3 atp methylorubrum extorquens 52.17 52.17 1 PMID:32505353 -6.3.4.3 atp neomoorella thermoacetica 6.08 3.535 2 PMID:12485612 -6.3.4.3 formate methylorubrum extorquens 68.65 68.65 1 PMID:32505353 -6.3.4.3 formate neomoorella thermoacetica 6.08 3.605 2 PMID:12485612 -6.3.4.3 tetrahydrofolate methylorubrum extorquens 66.32 66.32 1 PMID:32505353 -6.3.4.4 2'-dimp escherichia coli 0.96 0.96 1 PMID:16981730 -6.3.4.4 2'-dimp mus musculus 5.5 5.5 1 PMID:16981730 -6.3.4.4 gtp bacillus subtilis 0.47 0.47 1 PMID:25036129 -6.3.4.4 gtp escherichia coli 2.94 1.0 9 PMID:10218106;PMID:11781326;PMID:16981730;PMID:25036129;PMID:9632649 -6.3.4.4 gtp methanocaldococcus jannaschii 4.2 2.325 2 PMID:17929831 -6.3.4.4 gtp mus musculus 5.5 4.2 5 PMID:12482871;PMID:16981730 -6.3.4.4 gtp oryza sativa 0.98 0.79 2 PMID:25036129 -6.3.4.4 gtp plasmodium falciparum 1.1 1.1 1 PMID:15500910 -6.3.4.4 hydroxylamine escherichia coli 0.5 0.5 1 PMID:11781326 -6.3.4.4 imp escherichia coli 1.0 1.0 1 PMID:16981730 -6.3.4.4 imp methanocaldococcus jannaschii 4.2 2.325 2 PMID:17929831 -6.3.4.4 imp plasmodium falciparum 1.44 1.1 4 PMID:15500910;PMID:20654742;PMID:22289630 -6.3.4.4 l-asp escherichia coli 1.0 0.98 2 PMID:16981730 -6.3.4.4 l-asp mus musculus 5.5 5.5 1 PMID:16981730 -6.3.4.4 l-aspartate methanocaldococcus jannaschii 4.2 2.325 2 PMID:17929831 -6.3.4.4 l-aspartate plasmodium falciparum 1.1 1.1 1 PMID:15500910 -6.3.4.6 acetamide oleomonas sagaranensis 40.4 40.4 1 PMID:15090492 -6.3.4.6 formamide oleomonas sagaranensis 16.8 16.8 1 PMID:15090492 -6.3.4.6 urea kluyveromyces lactis 210.8 13.9 3 PMID:22277658;PMID:29263142 -6.3.4.6 urea oleomonas sagaranensis 44.2 44.2 1 PMID:15090492 -6.3.5.1 atp homo sapiens 18.5 11.145 2 PMID:31911602 -6.3.5.1 atp mycobacterium tuberculosis 2.9 1.75 2 PMID:19270703 -6.3.5.1 atp thermotoga maritima 0.15 0.15 1 PMID:19647806 -6.3.5.1 deamido-nad+ acinetobacter baumannii 0.57 0.57 2 PMID:20926389 -6.3.5.1 deamido-nad+ homo sapiens 23.4 13.299999999999999 2 PMID:31911602 -6.3.5.1 deamido-nad+ mycobacterium tuberculosis 2.6 1.55 2 PMID:19270703 -6.3.5.1 deamido-nad+ thermotoga maritima 0.16 0.16 1 PMID:19647806 -6.3.5.1 deamido-nmn acinetobacter baumannii 0.0032 0.0032 1 PMID:20926389 -6.3.5.1 l-gln mycobacterium tuberculosis 3.0 1.775 2 PMID:19270703 -6.3.5.1 l-gln thermotoga maritima 0.288 0.288 1 PMID:19647806 -6.3.5.1 l-glutamine azospirillum brasilense 0.23 0.135 2 PMID:29581233 -6.3.5.1 l-glutamine herbaspirillum seropedicae 0.09 0.09 1 PMID:29581233 -6.3.5.1 l-glutamine homo sapiens 3.72 3.72 1 PMID:31911602 -6.3.5.1 l-glutamine saccharomyces cerevisiae 6.4 6.4 1 PMID:16954203 -6.3.5.1 nh3 homo sapiens 20.0 20.0 1 PMID:31911602 -6.3.5.1 nh3 thermotoga maritima 0.24 0.24 1 PMID:19647806 -6.3.5.1 nh4+ azospirillum brasilense 0.23 0.14500000000000002 2 PMID:29581233 -6.3.5.1 nh4+ herbaspirillum seropedicae 0.07 0.07 1 PMID:29581233 -6.3.5.10 adenosylcobyrinic acid diamide salmonella enterica subsp. enterica serovar typhimurium 3.6 3.6 1 PMID:17212407 -6.3.5.10 adenosylcobyrinic acid pentaamide salmonella enterica subsp. enterica serovar typhimurium 8.4 8.4 1 PMID:17212407 -6.3.5.10 adenosylcobyrinic acid tetraamide salmonella enterica subsp. enterica serovar typhimurium 3.6 3.6 1 PMID:17212407 -6.3.5.10 adenosylcobyrinic acid triamide salmonella enterica subsp. enterica serovar typhimurium 2.4 2.4 1 PMID:17212407 -6.3.5.11 ammonia salmonella enterica subsp. enterica serovar typhimurium 0.18 0.18 1 PMID:15311923 -6.3.5.11 atp salmonella enterica subsp. enterica serovar typhimurium 0.13 0.13 1 PMID:15311923 -6.3.5.11 cobyrinate salmonella enterica subsp. enterica serovar typhimurium 0.16 0.16 1 PMID:15311923 -6.3.5.11 l-glutamine salmonella enterica subsp. enterica serovar typhimurium 0.16 0.16 1 PMID:15311923 -6.3.5.13 beta-d-glcnac-(1->4)-mur2ac(oyl-l-ala-gamma-d-glu-l-lys-d-ala-d-ala)-diphospho-ditrans,octacis-undecaprenol streptococcus pneumoniae 4.0 4.0 1 PMID:30093673 -6.3.5.2 atp aspergillus fumigatus 1657.0 1657.0 1 PMID:35102890 -6.3.5.2 atp mycobacterium tuberculosis 2.39 2.39 1 PMID:22119138 -6.3.5.2 atp plasmodium falciparum 0.43 0.43 1 PMID:17868038 -6.3.5.2 l-gln plasmodium falciparum 0.66 0.66 1 PMID:21413787 -6.3.5.2 l-glutamine escherichia coli 13.7 13.7 1 PMID:24434004 -6.3.5.2 l-glutamine mycobacterium tuberculosis 3.05 3.05 1 PMID:22119138 -6.3.5.2 l-glutamine plasmodium falciparum 0.43 0.43 1 PMID:17868038 -6.3.5.2 nh3 plasmodium falciparum 0.933 0.933 1 PMID:21413787 -6.3.5.2 nh4+ methanocaldococcus jannaschii 1.91 1.91 1 PMID:36040251 -6.3.5.2 xmp escherichia coli 23.0 18.15 2 PMID:24434004 -6.3.5.2 xmp mycobacterium tuberculosis 2.3 2.3 1 PMID:22119138 -6.3.5.2 xmp plasmodium falciparum 0.43 0.43 2 PMID:17868038 -6.3.5.3 nh4+ escherichia coli 0.05 0.05 1 PMID:2659070 -6.3.5.4 asp escherichia coli 1.05 0.81 2 PMID:7929415;PMID:9254614 -6.3.5.4 atp escherichia coli 2.94 0.96 9 PMID:12706338;PMID:20853825;PMID:7929415;PMID:9254614;PMID:9559053 -6.3.5.4 atp homo sapiens 1.7 1.65 2 PMID:16023613 -6.3.5.4 atp leishmania infantum 7.46 7.46 1 PMID:26771178 -6.3.5.4 atp vibrio cholerae serotype o1 5.8 5.8 1 PMID:14990305 -6.3.5.4 gln escherichia coli 0.59 0.59 1 PMID:7929415 -6.3.5.4 glutamine homo sapiens 1.7 1.7 1 PMID:16023613 -6.3.5.4 glutamine vibrio cholerae serotype o1 5.8 5.8 1 PMID:14990305 -6.3.5.4 hydroxylamine escherichia coli 1.03 1.03 1 PMID:8608142 -6.3.5.4 l-asp escherichia coli 0.75 0.71 4 PMID:20853825 -6.3.5.4 l-asparagine vibrio cholerae serotype o1 5.8 5.8 1 PMID:14990305 -6.3.5.4 l-aspartate escherichia coli 2.94 1.56 3 PMID:12706338;PMID:9559053 -6.3.5.4 l-aspartate leishmania infantum 9.19 9.19 1 PMID:26771178 -6.3.5.4 l-aspartic acid homo sapiens 1.7 1.5 2 PMID:16023613 -6.3.5.4 l-gln escherichia coli 6.6 6.2 3 PMID:20853825;PMID:8608142;PMID:9254614 -6.3.5.4 l-glutamic acid gamma-monohydroxamate escherichia coli 0.15 0.15 1 PMID:8608142 -6.3.5.4 l-glutamine escherichia coli 6.08 3.38 9 PMID:12706338;PMID:9559053 -6.3.5.4 l-glutamine leishmania infantum 4.51 4.51 1 PMID:26771178 -6.3.5.4 nh3 homo sapiens 1.8 1.8 1 PMID:16023613 -6.3.5.4 nh3 leishmania infantum 4.18 4.18 1 PMID:26771178 -6.3.5.4 nh4+ escherichia coli 0.59 0.59 1 PMID:8608142 -6.3.5.5 adp escherichia coli 0.13 0.13 1 PMID:20187643 -6.3.5.5 ammonia escherichia coli 5.1 5.1 1 PMID:12738780 -6.3.5.5 atp escherichia coli 8.0 3.475 10 PMID:12738780;PMID:14718657;PMID:18458150;PMID:20187643;PMID:9813025 -6.3.5.5 atp mammalia 2500.0 6.08 3 PMID:10497179;PMID:9813025 -6.3.5.5 gln escherichia coli 4.0 4.0 1 PMID:15081891 -6.3.5.5 l-gln escherichia coli 2.2 1.8 2 PMID:15122899;PMID:20187643 -6.3.5.5 l-glutamine escherichia coli 9.4 5.765000000000001 2 PMID:12738780;PMID:18458150 -6.3.5.5 l-glutamine mammalia 2660.0 2660.0 1 PMID:10497179 -6.3.5.5 nh4+ escherichia coli 3.9 2.9 2 PMID:15081891;PMID:15122899 -6.3.5.6 asp-trnaasn helicobacter pylori 1.3 0.775 2 PMID:17329242;PMID:22362756 -6.3.5.6 asp-trnagln helicobacter pylori 3.61 3.61 1 PMID:17329242 -6.3.5.6 atp helicobacter pylori 6.1 6.1 1 PMID:17329242 -6.3.5.6 gln helicobacter pylori 11.8 6.0 5 PMID:17329242 -6.3.5.6 l-aspartyl-trnaasn helicobacter pylori 0.027 0.027 1 PMID:17329242 -6.3.5.7 asp-trnaasn helicobacter pylori 1.3 1.3 1 PMID:17329242 -6.3.5.7 asp-trnagln helicobacter pylori 3.61 3.61 1 PMID:17329242 -6.3.5.7 atp helicobacter pylori 6.1 6.1 1 PMID:17329242 -6.3.5.7 atp streptococcus pyogenes 0.59 0.59 1 PMID:11371208 -6.3.5.7 gln helicobacter pylori 11.8 6.0 5 PMID:17329242 -6.3.5.7 gln streptococcus pyogenes 0.51 0.51 1 PMID:11371208 -6.3.5.7 glu-trnagln helicobacter pylori 0.23 0.21 3 PMID:21813455 -6.3.5.7 glu-trnagln methanothermobacter thermautotrophicus 1.2 0.9 3 PMID:20457752 -6.3.5.7 l-aspartyl-trnaasn helicobacter pylori 0.027 0.027 1 PMID:17329242 -6.3.5.7 l-glutamine saccharomyces cerevisiae 1.4 1.4 1 PMID:25149203 -6.3.5.7 trnagln1(uug) methanothermobacter thermautotrophicus 0.006 0.006 1 PMID:22158897 -6.3.5.7 trnagln2(cug) methanothermobacter thermautotrophicus 0.41 0.41 1 PMID:22158897 -6.3.5.7 trnaglu methanothermobacter thermautotrophicus 0.04 0.04 1 PMID:22158897 -6.3.5.9 atp salmonella enterica subsp. enterica serovar typhimurium 0.13 0.13 1 PMID:15311923 -6.3.5.9 cobyrinic acid salmonella enterica subsp. enterica serovar typhimurium 0.16 0.16 1 PMID:15311923 -6.3.5.9 cobyrinic acid c-monoamide salmonella enterica subsp. enterica serovar typhimurium 0.2 0.2 1 PMID:15311923 -6.3.5.9 glutamine salmonella enterica subsp. enterica serovar typhimurium 0.16 0.16 1 PMID:15311923 -6.3.5.9 nh4+ salmonella enterica subsp. enterica serovar typhimurium 0.18 0.18 1 PMID:15311923 -6.4.1.1 adp rhizobium etli 0.013 0.013 1 PMID:21958066 -6.4.1.1 atp gallus gallus 0.28 0.0049 5 PMID:10858297 -6.4.1.1 atp rhizobium etli 10.9 3.3249999999999997 4 PMID:21958066;PMID:22985389 -6.4.1.1 atp saccharomyces cerevisiae 60.0 30.0185 4 PMID:11914094;PMID:17478118 -6.4.1.1 carbamoyl phosphate saccharomyces cerevisiae 0.11 0.11 2 PMID:14744153 -6.4.1.1 hco3- rhizobium etli 11.6 11.6 1 PMID:21958066 -6.4.1.1 hco3- saccharomyces cerevisiae 60.0 60.0 2 PMID:17478118 -6.4.1.1 oxaloacetate aspergillus nidulans 33.83 32.83 2 PMID:29643369 -6.4.1.1 oxaloacetate rhizobium etli 2.167 0.183 7 PMID:23560609;PMID:24460480;PMID:29643369 -6.4.1.1 pyruvate aspergillus nidulans 9.5 8.2 2 PMID:33080172 -6.4.1.1 pyruvate gallus gallus 25.6 0.33 4 PMID:34411580 -6.4.1.1 pyruvate rhizobium etli 17.6 1.95 14 PMID:20230056;PMID:21958066;PMID:24460480;PMID:26149215;PMID:27379711;PMID:29655770;PMID:33080172;PMID:34411580 -6.4.1.1 pyruvate saccharomyces cerevisiae 60.0 60.0 2 PMID:17478118 -6.4.1.1 pyruvate staphylococcus aureus 15.7 11.1 2 PMID:19523900 -6.4.1.10 3-(4-hydroxyphenyl)pyruvate tapinella panuoides 0.292 0.292 1 PMID:18805498 -6.4.1.11 3-phenyl-2-oxopropanoate streptomyces sp. lz35 0.0058 0.0058 1 PMID:24865933 -6.4.1.12 (indol-3-yl)pyruvate aspergillus nidulans 1.72 1.295 2 PMID:17584611;PMID:17704773 -6.4.1.2 acetyl-coa acinetobacter baumannii 11.6 11.6 1 PMID:21704013 -6.4.1.2 acetyl-coa homo sapiens 11.8 6.5 4 PMID:16854592;PMID:17223360;PMID:19236960 -6.4.1.2 acetyl-coa klebsiella pneumoniae 30.1 30.1 1 PMID:21704013 -6.4.1.2 acetyl-coa metallosphaera sedula 8.0 8.0 3 PMID:12581213 -6.4.1.2 acetyl-coa rattus norvegicus 11.6 11.6 1 PMID:16854592 -6.4.1.2 atp homo sapiens 0.155 0.155 1 PMID:17223360 -6.4.1.2 atp saccharomyces cerevisiae 8.5 8.5 1 PMID:26458104 -6.4.1.3 acetyl-coa leptospira interrogans 0.66 0.66 1 PMID:22710261 -6.4.1.3 propanoyl-coa bacillus subtilis 0.4 0.4 1 PMID:32860966 -6.4.1.3 propanoyl-coa metallosphaera sedula 8.0 8.0 1 PMID:12581213 -6.4.1.3 propionyl-coa leptospira interrogans 2.86 2.86 1 PMID:22710261 -6.4.1.4 3-methylcrotonoyl-coa pseudomonas aeruginosa 0.96 0.96 1 PMID:23760555 -6.4.1.4 3-methylcrotonyl-coa homo sapiens 4.0 4.0 1 PMID:17360195 -6.4.1.4 atp homo sapiens 4.0 4.0 1 PMID:17360195 -6.4.1.6 acetone xanthobacter autotrophicus 1.33 1.33 1 PMID:12003937 -6.4.1.7 2-oxoglutarate hydrogenobacter thermophilus 30.6 30.6 1 PMID:17076668 -6.4.1.7 atp hydrogenobacter thermophilus 31.7 31.7 1 PMID:17076668 -6.5.1.1 (2e,6e)-farnesyl triphosphate tequatrovirus t4 0.0349 0.0349 1 PMID:19414000 -6.5.1.1 (deoxyribonucleotide)20 neisseria meningitidis 0.0018 0.0018 1 PMID:14730975 -6.5.1.1 (deoxyribonucleotide)n ferroplasma acidiphilum 0.056 0.056 1 PMID:18577594 -6.5.1.1 (nicked double-stranded dna)n psychromonas sp. sp041 0.05 0.05 1 PMID:25372693 -6.5.1.1 (single-stranded dna splinted by rna)m chlorella virus 0.008 0.008 1 PMID:24203707 -6.5.1.1 atp entamoeba histolytica 0.04 0.04 1 PMID:20603158 -6.5.1.1 atp homo sapiens 0.74 0.012 3 PMID:11698410;PMID:21561855 -6.5.1.1 clodronate tequatrovirus t4 0.0041 0.0041 1 PMID:18378215 -6.5.1.1 dimethylallyl diphosphate tequatrovirus t4 0.0492 0.0492 1 PMID:19414000 -6.5.1.1 dna bos taurus 0.117 0.117 1 PMID:6882774 -6.5.1.1 etidronate tequatrovirus t4 0.07 0.07 1 PMID:18378215 -6.5.1.1 farnesyl diphosphate tequatrovirus t4 0.0028 0.0028 1 PMID:19414000 -6.5.1.1 geranyl diphosphate tequatrovirus t4 0.0008 0.0008 1 PMID:19414000 -6.5.1.1 geranyl triphosphate tequatrovirus t4 0.0319 0.0319 1 PMID:19414000 -6.5.1.1 isopentenyl diphosphate tequatrovirus t4 0.0316 0.0316 1 PMID:19414000 -6.5.1.1 isopentenyl triphosphate tequatrovirus t4 0.0729 0.0729 1 PMID:19414000 -6.5.1.1 methylenebisphosphonate tequatrovirus t4 0.0006 0.0006 1 PMID:18378215 -6.5.1.1 nicked dna plasmodium falciparum 0.0023 0.0023 1 PMID:17688957 -6.5.1.1 nicked dna thermococcus kodakarensis 0.11 0.11 1 PMID:11856324 -6.5.1.1 tripolyphosphate tequatrovirus t4 0.0062 0.0062 1 PMID:18378215 -6.5.1.2 deoxyribonucleotide streptococcus pneumoniae 0.27 0.27 1 PMID:22743594 -6.5.1.2 dna melanoplus sanguinipes 0.4 0.4 1 PMID:15450174 -6.5.1.2 nad+ mycobacterium tuberculosis 0.072 0.072 1 PMID:14985346 -6.5.1.2 nad+ streptococcus pneumoniae 0.1 0.1 1 PMID:18795946 -6.5.1.2 nicked dna aquifex aeolicus 0.033 0.033 1 PMID:10684941 -6.5.1.2 nicked dna escherichia coli 0.03 0.018500000000000003 4 PMID:10848966;PMID:11812821 -6.5.1.2 nicked dna pseudoalteromonas haloplanktis 0.047 0.034 3 PMID:10848966 -6.5.1.2 nicked dna thermus scotoductus 0.132 0.0925 2 PMID:10848966 -6.5.1.3 (2e,6e)-farnesyl diphosphate tequatrovirus t4 12.1 12.1 1 PMID:19414000 -6.5.1.3 (2e,6e)-farnesyl triphosphate tequatrovirus t4 11.6 11.6 1 PMID:19414000 -6.5.1.3 (ribonucleotide)n+m synthetic construct 2.94 2.3 2 PMID:7618102 -6.5.1.3 (rna)n synthetic construct 6.08 2.33 7 PMID:10715133 -6.5.1.3 atp tequatrovirus t4 0.055 0.055 1 PMID:10215898 -6.5.1.3 clodronate tequatrovirus t4 0.29 0.29 1 PMID:17010342 -6.5.1.3 dimethylallyl diphosphate tequatrovirus t4 3.1 3.1 1 PMID:19414000 -6.5.1.3 etidronate tequatrovirus t4 0.028 0.028 1 PMID:17010342 -6.5.1.3 geranyl diphosphate tequatrovirus t4 8.6 8.6 1 PMID:19414000 -6.5.1.3 geranyl triphosphate tequatrovirus t4 52.2 52.2 1 PMID:19414000 -6.5.1.3 gtp tequatrovirus t4 0.017 0.017 1 PMID:10215898 -6.5.1.3 isopentenyl diphosphate tequatrovirus t4 0.9 0.9 1 PMID:19414000 -6.5.1.3 isopentenyl triphosphate tequatrovirus t4 6.7 6.7 1 PMID:19414000 -6.5.1.3 methylenebisphosphonate tequatrovirus t4 0.28 0.28 1 PMID:17010342 -6.5.1.6 nad+ homo sapiens 0.0088 0.0088 1 PMID:30496552 -6.5.1.8 (ribonucleotide)10-3'-phosphate pyrococcus horikoshii 0.00055 0.00036500000000000004 2 PMID:24435797 -6.5.1.8 (ribonucleotide)20-3'-phosphate thermobifida fusca 0.0014 0.0014 1 PMID:26385509 -6.5.1.8 (ribonucleotide)20-3'-phosphate thermus thermophilus 0.0122 0.00825 2 PMID:26385509 -6.5.1.9 2,3-diphospho-d-glycerate methanothermus fervidus 13.0 13.0 1 PMID:2226838 -6.5.1.9 atp methanothermus fervidus 13.0 13.0 1 PMID:2226838 -6.6.1.1 atp synechocystis sp. 0.0067 0.0067 1 PMID:23940041 -6.6.1.1 atp thermosynechococcus vestitus 0.0061 0.0061 1 PMID:24138165 -6.6.1.1 deuteroporphyrin synechocystis sp. 0.0188 0.0188 1 PMID:23940041 -6.6.1.1 deuteroporphyrin ix synechocystis sp. 0.013 0.013 1 PMID:15051720 -6.6.1.1 mg2+ synechocystis sp. 0.0081 0.0081 1 PMID:23940041 -6.6.1.1 mg2+ thermosynechococcus vestitus 0.0065 0.0065 1 PMID:24138165 -6.6.1.1 protoporphyrin ix chlorobaculum tepidum 0.03 0.0003 3 PMID:18693239 -6.7.1.2 3-amino-4-hydroxybenzoic acid streptomyces sp. ri-77 0.0022 0.0022 1 PMID:36115045 -6.7.1.2 3-aminoavenalumic acid streptomyces sp. ri-77 0.005 0.005 1 PMID:36115045 -6.7.1.2 atp streptomyces sp. ri-77 0.017 0.0106 2 PMID:36115045 -6.7.1.2 nitrite streptomyces sp. ri-77 0.00093 0.00093 1 PMID:36115045 -7.1.1.1 oxidized 3-acetylpyridine adenine dinucleotide rhodospirillum rubrum 1.44 0.73 2 PMID:8898902 -7.1.1.1 reduced acetylpyridine adenine dinucleotide escherichia coli 81.7 40.88335 2 PMID:11027139 -7.1.1.2 2,3-dimethoxy-5-methyl-6-[(6-methyl-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)methyl]benzo-1,4-quinone bos taurus 8.33 8.33 1 PMID:15465329 -7.1.1.2 2,3-dimethoxy-5-methyl-6-[(6-methylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]benzo-1,4-quinone bos taurus 81.73 81.73 1 PMID:15465329 -7.1.1.2 2,3-dimethoxy-5-methyl-6-[(6-phenylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]benzo-1,4-quinone bos taurus 23.88 23.88 1 PMID:15465329 -7.1.1.2 2-[(2,6-dimethylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-5,6-dimethoxy-3-methylbenzo-1,4-quinone bos taurus 11.22 11.22 1 PMID:15465329 -7.1.1.2 2-[(2-chloro-6-methylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-5,6-dimethoxy-3-methylbenzo-1,4-quinone bos taurus 42.95 42.95 1 PMID:15465329 -7.1.1.2 2-[(2-chloro-6-phenylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-5,6-dimethoxy-3-methylbenzo-1,4-quinone bos taurus 25.8 25.8 1 PMID:15465329 -7.1.1.2 2-[(6-chloro-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-5,6-dimethoxy-3-methylbenzo-1,4-quinone bos taurus 63.46 63.46 1 PMID:15465329 -7.1.1.2 2-[(6-chloro-2-methylimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-5,6-dimethoxy-3-methylbenzo-1,4-quinone bos taurus 76.28 76.28 1 PMID:15465329 -7.1.1.2 2-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)methyl]-5,6-dimethoxy-3-methylbenzo-1,4-quinone bos taurus 62.82 62.82 1 PMID:15465329 -7.1.1.2 coenzyme q0 bos taurus 47.69 47.69 1 PMID:15465329 -7.1.1.2 coenzyme q1 bos taurus 211.5 211.5 1 PMID:15465329 -7.1.1.2 hexaammineruthenium-iii-chloride escherichia coli 1500.0 1500.0 1 PMID:15938640 -7.1.1.2 menadione plasmodium falciparum 0.077 0.077 1 PMID:19097788 -7.1.1.2 menaquinone mycobacterium tuberculosis 423.0 423.0 1 PMID:24447297 -7.1.1.2 nadh bos taurus 2.7 2.7 1 PMID:19220002 -7.1.1.2 nadh escherichia coli 26.0 26.0 1 PMID:21832062 -7.1.1.2 nadh saccharomyces cerevisiae 550.0 325.0 2 PMID:3138118 -7.1.1.2 nadh thermus thermophilus 1.1 1.0 2 PMID:23370906 -7.1.1.2 nadph escherichia coli 3.0 3.0 1 PMID:21832062 -7.1.1.2 oxidized dichlorophenolindophenol plasmodium falciparum 0.032 0.032 1 PMID:19097788 -7.1.1.2 ubiquinone-0 mycobacterium tuberculosis 480.0 480.0 1 PMID:24447297 -7.1.1.2 ubiquinone-0 plasmodium falciparum 0.33 0.33 1 PMID:19097788 -7.1.1.2 ubiquinone-1 plasmodium falciparum 664.0 332.0075 2 PMID:19097788;PMID:28195463 -7.1.1.2 ubiquinone-2 mycobacterium tuberculosis 640.0 640.0 1 PMID:24447297 -7.1.1.3 ubiquinol-1 escherichia coli 341.0 320.5 2 PMID:8382081 -7.1.1.4 caldariellaquinol sulfolobus acidocaldarius 393.0 316.0 2 PMID:9079667 -7.1.1.4 ferrocytochrome c aeropyrum pernix 1.5 1.5 1 PMID:12471503 -7.1.1.4 n,n,n',n'-tetramethyl-1,4-phenylenediamine aeropyrum pernix 66.9 66.9 1 PMID:12471503 -7.1.1.4 n,n,n',n'-tetramethyl-1,4-phenylenediamine sulfolobus acidocaldarius 404.0 280.5 2 PMID:9079667 -7.1.1.5 2,3-dimethyl-1,4-naphthoquinone bacillus subtilis 65.0 63.0 2 PMID:11683643;PMID:20351111 -7.1.1.5 dimethylnitrosamine bacillus subtilis 180.0 180.0 1 PMID:26196462 -7.1.1.6 cytochrome c1 trichormus variabilis 0.333 0.333 1 PMID:6307358 -7.1.1.6 cytochrome f chlamydomonas reinhardtii 5.0 5.0 1 PMID:7493968 -7.1.1.6 cytochrome f spinacia oleracea 34.0 34.0 1 PMID:3813555;PMID:6269845 -7.1.1.7 h2o2[side 2] escherichia coli 101.0 101.0 1 PMID:27279363 -7.1.1.8 2 ferricytochrome c paracoccus denitrificans 919.0 170.0 3 PMID:18774933;PMID:3017970 -7.1.1.8 2 ferricytochrome c1 bacillus sp. (in: firmicutes) 0.833 0.833 1 PMID:2163487 -7.1.1.8 2 ferricytochrome c1 paracoccus denitrificans 11.7 11.7 1 PMID:2163487 -7.1.1.8 2 ferricytochrome c1 rhodobacter capsulatus 1.17 1.17 1 PMID:2163487 -7.1.1.8 2 ferricytochrome c1 rhodospirillum rubrum 3.9 2.575 2 PMID:2163487;PMID:2548618 -7.1.1.8 2 ferricytochrome c1 trichormus variabilis 0.333 0.333 1 PMID:2163487;PMID:6307358 -7.1.1.8 2 horse heart ferricytochrome c1 cereibacter sphaeroides 5.0 5.0 1 PMID:2161250 -7.1.1.8 2,3-dimethoxy-5-methyl-6-(10-bromodecyl)-1,4-benzoquinol rhodospirillum rubrum 66.7 66.7 1 PMID:2548618 -7.1.1.8 cytochrome c bos taurus 66.7 11.8 4 PMID:3017970;PMID:9287166 -7.1.1.8 cytochrome c cereibacter sphaeroides 35.0 30.0 2 PMID:2161250;PMID:6295373 -7.1.1.8 cytochrome c saccharomyces cerevisiae 82.0 82.0 1 PMID:12782631 -7.1.1.8 cytochrome c1 bos taurus 66.7 66.7 1 PMID:6307358;PMID:6321316 -7.1.1.8 cytochrome c1 cereibacter sphaeroides 3.0 1.5665 2 PMID:2163487;PMID:6307358 -7.1.1.8 cytochrome c1 neurospora crassa 0.333 0.333 1 PMID:2163487 -7.1.1.8 cytochrome c1 saccharomyces cerevisiae 5.08 4.205 2 PMID:2163487;PMID:6307358 -7.1.1.8 decylubiquinol saccharomyces cerevisiae 240.0 143.0 3 PMID:11700316;PMID:16087663;PMID:16987808 -7.1.1.8 rhodoquinol-3 saccharomyces cerevisiae 76.0 76.0 1 PMID:16087663 -7.1.1.8 ubihydroquinone bos taurus 28.3 28.3 1 PMID:9287166 -7.1.1.8 ubiquinol saccharomyces cerevisiae 160.0 160.0 1 PMID:14670947 -7.1.1.9 cytochrome c eukaryota 100.0 100.0 1 PMID:2821746 -7.1.1.9 diaminodurene micrococcus luteus 15.3 15.3 1 PMID:2821914 -7.1.1.9 ferrocytochrome c ancylobacter novellus 45.8 40.0 3 PMID:6248108;PMID:6263325 -7.1.1.9 ferrocytochrome c bacillus subtilis 16.0 7.0 5 PMID:2856123;PMID:3038545;PMID:6299734 -7.1.1.9 ferrocytochrome c bacteria 600.0 350.0 2 PMID:2157476;PMID:2821746 -7.1.1.9 ferrocytochrome c bos taurus 500.0 56.0 4 PMID:12605676;PMID:2821746;PMID:6263325 -7.1.1.9 ferrocytochrome c carcharhinus acronotus 360.0 360.0 1 PMID:8840511 -7.1.1.9 ferrocytochrome c carcharhinus limbatus 350.0 350.0 1 PMID:8840511 -7.1.1.9 ferrocytochrome c cereibacter sphaeroides 2000.0 649.0 10 PMID:10608872;PMID:17910921;PMID:2856120;PMID:6286309;PMID:9054559;PMID:9693057 -7.1.1.9 ferrocytochrome c crithidia fasciculata 111.0 111.0 1 PMID:8844671 -7.1.1.9 ferrocytochrome c dictyostelium discoideum 300.0 229.0 2 * -7.1.1.9 ferrocytochrome c erythrobacter longus 66.0 45.0 2 PMID:2830243 -7.1.1.9 ferrocytochrome c eukaryota 600.0 600.0 1 PMID:2157476 -7.1.1.9 ferrocytochrome c homo sapiens 80.0 55.0 2 * -7.1.1.9 ferrocytochrome c micrococcus luteus 9.38 9.38 1 * -7.1.1.9 ferrocytochrome c nitrobacter winogradskyi 290.0 160.0 5 PMID:6260762 -7.1.1.9 ferrocytochrome c nitrosomonas europaea 336.0 14.0 7 PMID:2542236 -7.1.1.9 ferrocytochrome c paracoccus denitrificans 90.0 90.0 1 PMID:6263325 -7.1.1.9 ferrocytochrome c paramagnetospirillum magnetotacticum 187.0 187.0 1 PMID:8013655 -7.1.1.9 ferrocytochrome c pseudomonas sp. 91.0 91.0 1 PMID:2999096 -7.1.1.9 ferrocytochrome c rattus norvegicus 200.0 133.0 3 PMID:212102;PMID:7601105 -7.1.1.9 ferrocytochrome c rhizoprionodon terraenovae 410.0 395.0 2 PMID:8840511 -7.1.1.9 ferrocytochrome c saccharomyces cerevisiae 1500.0 1500.0 1 PMID:7851399 -7.1.1.9 ferrocytochrome c sphyrna lewini 36.0 36.0 1 PMID:6244291 -7.1.1.9 ferrocytochrome c squalus acanthias 30.0 30.0 1 PMID:6244291 -7.1.1.9 ferrocytochrome c sus scrofa 550.0 530.0 4 PMID:2856135 -7.1.1.9 ferrocytochrome c thermus thermophilus 53.0 8.33 3 * -7.1.1.9 ferrocytochrome c triticum aestivum 1000.0 1000.0 1 PMID:2176829 -7.1.1.9 ferrocytochrome c549 erythrobacter longus 8.0 8.0 1 PMID:2830243 -7.1.1.9 ferrocytochrome c550 erythrobacter longus 1.3 1.3 1 PMID:2830243 -7.1.1.9 ferrocytochrome c550 paramagnetospirillum magnetotacticum 37.4 37.4 1 PMID:8013655 -7.1.1.9 ferrocytochrome c552 nitrosomonas europaea 4.0 4.0 1 PMID:2542236 -7.1.1.9 ferrocytochrome c552 thermus thermophilus 9.78 9.78 1 PMID:6244813 -7.1.1.9 ferrocytochrome c553 helicobacter pylori 252.0 252.0 1 PMID:9880817 -7.1.1.9 n,n,n',n'-tetramethyl-4-phenylendiamine bacillus subtilis 220.0 220.0 1 PMID:7619069 -7.1.1.9 n,n,n',n'-tetramethyl-4-phenylendiamine micrococcus luteus 3.93 3.93 1 PMID:2821914 -7.1.1.9 n,n,n',n'-tetramethyl-4-phenylendiamine stutzerimonas stutzeri 180.0 180.0 1 PMID:11707262 -7.1.1.9 n,n,n',n'-tetramethyl-4-phenylendiamine thermus thermophilus 60.0 33.75 2 PMID:6244539;PMID:6263325 -7.1.1.9 phenazine methosulfate micrococcus luteus 24.3 24.3 1 PMID:2821914 -7.1.1.9 reduced cytochrome c551 geobacillus thermodenitrificans 295.0 295.0 1 PMID:20226371 -7.1.2.1 atp arabidopsis thaliana 56.7 56.7 1 PMID:9473454 -7.1.2.1 atp kluyveromyces lactis 6.0 6.0 1 PMID:17439159 -7.1.2.2 adp bacillus sp. (in: firmicutes) 17.0 17.0 1 PMID:21605343 -7.1.2.2 adp escherichia coli 16.0 16.0 1 PMID:19411254 -7.1.2.2 atp bacillus sp. (in: firmicutes) 390.0 390.0 1 PMID:24876384 -7.1.2.2 atp bacillus sp. ps3 5.34 5.34 1 PMID:19733568 -7.1.2.2 atp escherichia coli 285.0 285.0 1 PMID:19411254 -7.1.2.2 atp geobacillus stearothermophilus 217.0 217.0 1 * -7.1.2.2 atp shigella flexneri 0.15 0.15 1 PMID:30013545 -7.1.2.2 phosphate bacillus sp. (in: firmicutes) 16.0 16.0 1 PMID:21605343 -7.1.2.2 phosphate escherichia coli 20.0 20.0 1 PMID:19411254 -7.1.3.1 diphosphate ascaris suum 638.0 638.0 1 PMID:12823552 -7.1.3.1 diphosphate bacillus sp. ps3 817.0 817.0 1 PMID:11754735 -7.1.3.1 diphosphate leishmania amazonensis 125.0 125.0 1 PMID:16291745 -7.1.3.1 diphosphate trypanosoma brucei 385.0 220.5 2 PMID:14615483 -7.1.3.1 polyphosphate trypanosoma brucei 3.5 3.5 1 PMID:14615483 -7.1.3.1 polyphosphate-n28 leishmania amazonensis 8.0 8.0 1 PMID:16291745 -7.1.3.1 triphosphate leishmania amazonensis 131.0 131.0 1 PMID:16291745 -7.1.3.1 tripolyphosphate trypanosoma brucei 52.0 52.0 1 PMID:14615483 -7.2.1.1 n li+/in vibrio cholerae serotype o1 180.0 180.0 1 PMID:24030824 -7.2.1.1 n na+/in vibrio cholerae serotype o1 500.0 500.0 1 PMID:24030824 -7.2.1.1 nadh vibrio cholerae serotype o1 600.1 587.2 3 PMID:24030824 -7.2.1.1 ubiquinone vibrio cholerae serotype o1 525.0 525.0 1 PMID:22645140 -7.2.1.1 ubiquinone-1 vibrio cholerae serotype o1 528.5 365.25 4 PMID:22645140;PMID:24030824 -7.2.2.10 atp homo sapiens 130.0 21.384999999999998 6 PMID:16192278 -7.2.2.10 ca2+ homo sapiens 149.0 116.0 6 PMID:12207029 -7.2.2.10 ca2+ oryctolagus cuniculus 128.0 95.0 3 PMID:12207029;PMID:16040761 -7.2.2.12 atp noccaea caerulescens 300.0 300.0 1 PMID:21621506 -7.2.2.13 k+ oryctolagus cuniculus 8.0 7.0 2 PMID:15817632 -7.2.2.13 na+/in octopus bimaculatus 20.1 20.1 1 PMID:21653810 -7.2.2.13 na+/in pareledone sp. 25.5 25.5 1 PMID:21653810 -7.2.2.14 mg2+[side 1] escherichia coli 23.0 22.5 2 PMID:26780187 -7.2.2.8 4-nitrophenyl phosphate archaeoglobus fulgidus 5.9 5.9 1 PMID:27086711 -7.2.2.8 atp archaeoglobus fulgidus 0.26 0.26 1 PMID:27086711 -7.2.3.1 na+[side 1] thermotoga maritima 12.0 8.65 2 PMID:36040263 -7.4.2.3 atp homo sapiens 0.00068 0.00068 1 PMID:18632665 -7.4.2.5 atp escherichia coli 0.33 0.2 5 PMID:15636583;PMID:16008353 -7.4.2.5 atp homo sapiens 5.0 5.0 1 PMID:11274390 -7.4.2.5 atp saccharomyces cerevisiae 25.0 25.0 1 PMID:12746444 -7.4.2.6 atp homo sapiens 1.08 0.48 3 PMID:31417173 -7.4.2.6 rryqkstel-[rryqkstel-binding protein][side 1] homo sapiens 0.069 0.069 1 PMID:31417173 -7.4.2.6 rryqkstelrryqkstel-[rryqkstelrryqkstel-binding protein][side 1] homo sapiens 0.004 0.004 1 PMID:31417173 -7.4.2.6 yck(k8)stel-[yck(k8)stel-binding protein][side 1] homo sapiens 0.004 0.004 1 PMID:31417173 -7.4.2.8 atp escherichia coli 0.35 0.3195 2 PMID:17964526;PMID:27864920 -7.4.2.8 atp legionella pneumophila 674.0 674.0 2 PMID:29770512 -7.4.2.8 atp pseudomonas syringae 447.0 223.526 2 PMID:12734178 -7.4.2.8 atp shigella flexneri 1.18 0.84 3 PMID:26947936;PMID:29595954;PMID:30013545 -7.4.2.8 atp xanthomonas campestris 0.00525 0.00405 4 PMID:17630971 -7.4.2.9 l-ala-l-gamma-glu-l-leu-[l-ala-l-gamma-glu-l-leu-binding protein][side 1] escherichia coli 24.4 24.4 1 PMID:29728377 -7.4.2.9 l-ala-l-gamma-glu-l-phe-l-leu-[l-ala-l-gamma-glu-l-phe-l-leu-binding protein][side 1] escherichia coli 8.31 8.31 1 PMID:29728377 -7.5.2.1 atp escherichia coli 7.8 1.2 3 PMID:26338707 -7.5.2.2 atp escherichia coli 0.33 0.255 4 PMID:15636583 -7.6.2.2 atp bos taurus 0.078 0.078 1 PMID:28238471 -7.6.2.2 atp homo sapiens 2.95 2.38 3 PMID:19490125 -7.6.2.2 colchicine/in homo sapiens 7.81 6.4 3 PMID:19490125 -7.6.2.2 digoxin/in homo sapiens 5.99 5.65 3 PMID:19490125 -7.6.2.2 nicardipine/in homo sapiens 8.44 7.8 3 PMID:19490125 -7.6.2.2 paclitaxel/in homo sapiens 2.2 1.5 3 PMID:19490125 -7.6.2.2 rhodamine 123/in homo sapiens 8.56 8.19 3 PMID:19490125 -7.6.2.2 rhodamine b/in homo sapiens 7.22 6.99 3 PMID:19490125 -7.6.2.2 verapamil homo sapiens 5.8 5.8 1 PMID:12244102 -7.6.2.2 verapamil/in homo sapiens 8.27 7.71 3 PMID:19490125 -7.6.2.2 vinblastine/in homo sapiens 6.54 6.39 3 PMID:19490125 -7.6.2.8 atp escherichia coli 1.39 0.845 2 PMID:21345797 -7.6.2.9 atp bacillus subtilis 0.25 0.020999999999999998 4 PMID:14623183 diff --git a/databases/mw.tsv b/databases/mw.tsv deleted file mode 100644 index c4e67411..00000000 --- a/databases/mw.tsv +++ /dev/null @@ -1,27759 +0,0 @@ -# BRENDA release 2026.1 generated 2026-05-28 - CC BY 4.0 - molecular weight in g/mol -ec_code substrate organism mw n references -1.1.1.1 * [candida] maris 59900.0 2 PMID:21670533 -1.1.1.1 * [candida] sp. 180000.0 2 * -1.1.1.1 * acetobacter pasteurianus 130000.0 4 PMID:12834271 -1.1.1.1 * aeropyrum pernix 160000.0 3 PMID:16233615;PMID:17072683 -1.1.1.1 * arabidopsis thaliana 80000.0 2 PMID:23707506 -1.1.1.1 * aspergillus nidulans 290000.0 2 PMID:3156582 -1.1.1.1 * bacillus subtilis 164000.0 1 PMID:28320283 -1.1.1.1 * bombyx mori 31000.0 1 PMID:21734824 -1.1.1.1 * brevibacterium sp. 39000.0 2 PMID:16243283 -1.1.1.1 * camellia sinensis 150000.0 1 PMID:16463078;PMID:25082080 -1.1.1.1 * candida parapsilosis 31000.0 2 PMID:16391048;PMID:17435004 -1.1.1.1 * carboxydothermus hydrogenoformans 30000.0 1 PMID:23160740 -1.1.1.1 * chlamydomonas moewusii 94000.0 2 * -1.1.1.1 * chlamydomonas reinhardtii 440000.0 1 PMID:28007962 -1.1.1.1 * corynebacterium glutamicum r 81500.0 2 PMID:17646983 -1.1.1.1 * coturnix coturnix 82750.0 2 PMID:2789998 -1.1.1.1 * ctenopharyngodon idella 28000.0 1 * -1.1.1.1 * devosia riboflavina 58000.0 2 PMID:2943270 -1.1.1.1 * drosophila melanogaster 55600.0 2 PMID:6796069 -1.1.1.1 * drosophila simulans 57600.0 2 PMID:6796069 -1.1.1.1 * drosophila virilis 54600.0 2 PMID:6796069 -1.1.1.1 * entamoeba histolytica 96000.0 1 PMID:12058720 -1.1.1.1 * euglena gracilis 37000.0 1 PMID:19120802 -1.1.1.1 * flavobacterium frigidimaris 160000.0 2 PMID:16233615;PMID:17072683 -1.1.1.1 * fragaria x ananassa 25000.0 2 PMID:16390205 -1.1.1.1 * gallus gallus 40000.0 1 PMID:21329683;PMID:2936344;PMID:658420;PMID:8612630 -1.1.1.1 * geobacillus stearothermophilus 158000.0 2 PMID:8729010 -1.1.1.1 * geobacillus thermodenitrificans 380000.0 1 PMID:19383697 -1.1.1.1 * glycine max 74000.0 1 * -1.1.1.1 * haloferax volcanii 138000.0 2 PMID:22526808 -1.1.1.1 * homo sapiens 85000.0 17 PMID:18242813;PMID:21329683;PMID:2936344;PMID:3282541;PMID:427099;PMID:6375718;PMID:6397223;PMID:640168;PMID:658420;PMID:7011320;PMID:7011375;PMID:836289;PMID:8612630;PMID:8730210 -1.1.1.1 * hordeum vulgare 91000.0 2 * -1.1.1.1 * kangiella koreensis 40000.0 2 PMID:25481533 -1.1.1.1 * kluyveromyces marxianus 200000.0 10 PMID:17485854;PMID:24885162 -1.1.1.1 * leifsonia sp. 110000.0 2 PMID:16000771 -1.1.1.1 * macaca mulatta 77000.0 1 PMID:7030395 -1.1.1.1 * megalodesulfovibrio gigas 320000.0 2 PMID:8491707 -1.1.1.1 * mesocricetus auratus 80000.0 3 PMID:3178842;PMID:3282541;PMID:3816781;PMID:427099;PMID:6375718;PMID:640168;PMID:7011375;PMID:8730210 -1.1.1.1 * methylorubrum extorquens 45000.0 1 PMID:16390205 -1.1.1.1 * meyerozyma guilliermondii 152000.0 2 PMID:19139244 -1.1.1.1 * mus musculus 85000.0 6 PMID:6360682 -1.1.1.1 * mycobacterium sp. 150000.0 2 PMID:16463078;PMID:25082080 -1.1.1.1 * natronomonas pharaonis 41300.0 1 PMID:18189118 -1.1.1.1 * neurospora crassa 37983.0 2 PMID:17516063 -1.1.1.1 * oenococcus oeni 74000.0 1 PMID:23385476 -1.1.1.1 * oncorhynchus mykiss 80000.0 2 PMID:3178842;PMID:3282541;PMID:3816781;PMID:427099;PMID:6375718;PMID:640168;PMID:7011375;PMID:8730210 -1.1.1.1 * oryctolagus cuniculus 74500.0 4 PMID:2916992;PMID:3161873 -1.1.1.1 * oryza sativa 86000.0 2 * -1.1.1.1 * parageobacillus thermoglucosidasius 99000.0 4 PMID:24100328 -1.1.1.1 * petroselinum crispum 68000.0 2 PMID:1463738;PMID:3115775;PMID:7770449 -1.1.1.1 * picrophilus oshimae 35000.0 1 PMID:17989975 -1.1.1.1 * polytomella sp. pringsheim 198.80 91480.0 3 PMID:14756315 -1.1.1.1 * pseudomonas fluorescens 31997.0 1 PMID:12172614 -1.1.1.1 * pseudomonas putida 57000.0 2 PMID:16926497 -1.1.1.1 * pyrobaculum calidifontis 76000.0 1 PMID:29022135 -1.1.1.1 * pyrococcus furiosus 150000.0 5 PMID:16391048;PMID:16463078;PMID:17435004;PMID:25082080 -1.1.1.1 * rattus norvegicus 80000.0 4 PMID:3178842;PMID:3816781;PMID:640168;PMID:8730210 -1.1.1.1 * rhodococcus ruber 72000.0 4 PMID:15007841;PMID:22584819 -1.1.1.1 * saara hardwickii 40000.0 1 PMID:21329683;PMID:2936344;PMID:658420;PMID:8612630 -1.1.1.1 * saccharolobus solfataricus 150300.0 11 PMID:10074357;PMID:11265460;PMID:1463738;PMID:17824633;PMID:3115775;PMID:7770449;PMID:8550434 -1.1.1.1 * saccharomyces cerevisiae 80000.0 2 PMID:3282541;PMID:427099;PMID:6375718;PMID:640168;PMID:7011375;PMID:8730210 -1.1.1.1 * saimiri sciureus 77330.0 2 PMID:3282541;PMID:427099;PMID:6375718;PMID:640168;PMID:7011375;PMID:8730210 -1.1.1.1 * scaptodrosophila lebanonensis 56000.0 2 PMID:2943270 -1.1.1.1 * scyliorhinus canicula 40000.0 1 PMID:21329683;PMID:2936344;PMID:658420;PMID:8612630 -1.1.1.1 * sporotrichum pulverulentum 176000.0 2 * -1.1.1.1 * sulfolobus acidocaldarius 109000.0 5 PMID:20049620;PMID:22805786 -1.1.1.1 * sulfolobus sp. 140000.0 2 PMID:8550434 -1.1.1.1 * sulfurisphaera tokodaii 133000.0 3 PMID:19139244 -1.1.1.1 * thermoanaerobacter ethanolicus 100000.0 1 PMID:17981479 -1.1.1.1 * thermococcus kodakarensis 31464.0 3 PMID:23354700 -1.1.1.1 * thermomicrobium roseum 88000.0 2 PMID:12031468 -1.1.1.1 * thermoplasma acidophilum 36010.0 2 PMID:19058034 -1.1.1.1 * thermus sp. 40000.0 2 PMID:18704396 -1.1.1.1 * thermus thermophilus 105000.0 2 PMID:18456852 -1.1.1.1 * triticum monococcum 116000.0 2 PMID:16661226;PMID:485168 -1.1.1.1 * triticum turgidum 116000.0 2 PMID:16661226;PMID:485168 -1.1.1.1 * vicia faba 30000.0 1 * -1.1.1.1 * yokenella sp. 37000.0 2 PMID:24509923 -1.1.1.1 * zea mays 70000.0 2 * -1.1.1.1 * zymomonas mobilis 145000.0 8 PMID:7030207 -1.1.1.10 * aspergillus niger 250000.0 2 * -1.1.1.10 * cricetinae 40000.0 1 PMID:11306103 -1.1.1.10 * erwinia sp. 102000.0 1 PMID:3886639 -1.1.1.10 * mesocricetus auratus 31000.0 1 PMID:15293214 -1.1.1.10 * pantoea ananatis 136000.0 1 PMID:2981816 -1.1.1.10 * rattus norvegicus 26500.0 1 PMID:12604240 -1.1.1.10 * rhizomucor pusillus 98000.0 1 PMID:28471330 -1.1.1.10 * trichoderma reesei 31000.0 1 PMID:23506391 -1.1.1.100 * arabidopsis thaliana 35000.0 1 PMID:19439572 -1.1.1.100 * aurantiochytrium limacinum 351500.0 1 PMID:30533058 -1.1.1.100 * bacillus subtilis 24000.0 1 PMID:8759840 -1.1.1.100 * brassica napus 120000.0 1 PMID:1562581 -1.1.1.100 * cuphea lanceolata 27000.0 1 PMID:1376402 -1.1.1.100 * euglena gracilis 44000.0 1 PMID:6766450 -1.1.1.100 * lactococcus lactis 25000.0 2 PMID:15362862 -1.1.1.100 * mycolicibacterium smegmatis 133000.0 2 PMID:28126742;PMID:29717709 -1.1.1.100 * persea americana 130000.0 3 PMID:2244875;PMID:7075600 -1.1.1.100 * plasmodium falciparum 28000.0 1 PMID:12646215 -1.1.1.100 * pseudomonas aeruginosa 116000.0 5 PMID:16624803 -1.1.1.100 * pseudomonas putida 25500.0 1 PMID:18691538 -1.1.1.100 * spinacia oleracea 97000.0 3 PMID:16662382;PMID:6756317 -1.1.1.100 * synechococcus elongatus pcc 7942 = fachb-805 102000.0 2 PMID:18791006 -1.1.1.100 * vibrio cholerae serotype o1 25000.0 1 PMID:26553852 -1.1.1.100 * xanthomonas campestris pv. campestris 26400.0 1 PMID:29739899 -1.1.1.101 * cavia porcellus 75000.0 3 PMID:1495422;PMID:2335525 -1.1.1.101 * saccharomyces cerevisiae 33000.0 1 PMID:10617610 -1.1.1.102 * homo sapiens 150000.0 1 PMID:19141869 -1.1.1.102 * saccharomyces cerevisiae 150000.0 1 PMID:19141869 -1.1.1.103 * acetoanaerobium sticklandii 80000.0 2 PMID:7763136 -1.1.1.103 * capra hircus 89000.0 3 PMID:12867457;PMID:3888978 -1.1.1.103 * cupriavidus necator 79400.0 2 PMID:21073854 -1.1.1.103 * cytophaga sp. 139000.0 2 PMID:12867457;PMID:3888978 -1.1.1.103 * escherichia coli 40000.0 1 PMID:24651643 -1.1.1.103 * escherichia coli k-12 140000.0 1 PMID:6780553 -1.1.1.103 * gallus gallus 88000.0 4 PMID:11470445;PMID:7028754 -1.1.1.103 * mus musculus 41500.0 1 PMID:12097150 -1.1.1.103 * pyrococcus furiosus 155000.0 3 PMID:16817900 -1.1.1.103 * pyrococcus horikoshii 192000.0 7 PMID:15902509;PMID:16233775;PMID:16511061;PMID:17188300 -1.1.1.103 * sus scrofa 73000.0 4 PMID:12097150;PMID:7827500 -1.1.1.103 * thermococcus kodakarensis 38016.0 1 PMID:18765916;PMID:19616102 -1.1.1.103 * thermococcus kodakarensis kod1 154000.0 2 PMID:19307254 -1.1.1.103 * thermoplasma volcanium 77000.0 3 PMID:22374996 -1.1.1.105 * drosophila melanogaster 30300.0 1 PMID:27809489 -1.1.1.105 * homo sapiens 40000.0 3 PMID:12534290;PMID:18599039;PMID:19102727 -1.1.1.105 * kangiella koreensis 80000.0 5 PMID:25481533 -1.1.1.106 * pseudomonas fluorescens 86000.0 3 PMID:99175 -1.1.1.107 * mesorhizobium loti 98000.0 6 PMID:16824480;PMID:20516609 -1.1.1.107 * microbacterium luteolum 84000.0 4 PMID:12005047;PMID:15226311 -1.1.1.108 * agrobacterium sp. 114000.0 2 PMID:8645721 -1.1.1.108 * alcaligenes sp. 51000.0 1 PMID:8645721 -1.1.1.108 * bacteria 35000.0 1 * -1.1.1.108 * pseudomonas putida 60000.0 2 PMID:3058208 -1.1.1.108 * rhizobium sp. 50000.0 1 PMID:23794271 -1.1.1.108 * rhizobium sp. ys-240 110000.0 2 * -1.1.1.108 * xanthomonas translucens 74000.0 3 PMID:23794271 -1.1.1.11 * candida albicans 30643.0 1 PMID:8407803 -1.1.1.11 * candida tropicalis 31000.0 2 PMID:7698655;PMID:8250887 -1.1.1.11 * gluconobacter oxydans 140000.0 5 PMID:19629658 -1.1.1.11 * klebsiella aerogenes 46500.0 4 PMID:393250 -1.1.1.11 * scheffersomyces stipitis 110000.0 2 PMID:7483848 -1.1.1.110 * candida maltosa 280000.0 3 * -1.1.1.112 * macaca fuscata 38000.0 2 PMID:2674111 -1.1.1.112 * oryctolagus cuniculus 36000.0 7 PMID:3527067 -1.1.1.113 * haloferax mediterranei 89000.0 2 PMID:8925901 -1.1.1.114 * micrococcus sp. 115000.0 2 * -1.1.1.116 * candida albicans 42000.0 2 PMID:8841374 -1.1.1.116 * neurospora crassa 60000.0 2 PMID:6450742 -1.1.1.116 * phycomyces blakesleeanus 41000.0 1 PMID:15809004 -1.1.1.116 * saccharomyces cerevisiae 42400.0 2 PMID:17097644 -1.1.1.116 * sus scrofa 245000.0 1 PMID:4355268 -1.1.1.117 * candida albicans 42000.0 2 PMID:8841374 -1.1.1.117 * pseudomonas sp. 104000.0 3 PMID:5845849 -1.1.1.118 * bacillus subtilis 30000.0 1 PMID:27516945 -1.1.1.118 * saccharolobus solfataricus 124000.0 3 PMID:3827812 -1.1.1.119 * gluconobacter oxydans 153000.0 2 * -1.1.1.119 * haloferax mediterranei 89000.0 4 PMID:16511145;PMID:8925901 -1.1.1.12 * meyerozyma caribbica 195000.0 1 PMID:27506274 -1.1.1.12 * neurospora crassa 152000.0 3 PMID:17938906 -1.1.1.12 * rasamsonia emersonii 45000.0 2 PMID:20111899 -1.1.1.12 * trichoderma reesei 40000.0 1 PMID:24342239 -1.1.1.121 * pseudomonas sp. 140000.0 3 PMID:5845849 -1.1.1.121 * thermoplasma acidophilum 85000.0 2 PMID:15618614 -1.1.1.121 * thermus thermophilus hb8 100000.0 2 PMID:18926808 -1.1.1.122 * acinetobacter sp. 25000.0 2 PMID:24320238 -1.1.1.122 * agrobacterium tumefaciens 100000.0 4 PMID:1525177 -1.1.1.122 * aureobasidium pullulans 40000.0 1 * -1.1.1.122 * oryctolagus cuniculus 92000.0 1 PMID:521443 -1.1.1.122 * ovis aries aries 123000.0 4 PMID:236435;PMID:629533 -1.1.1.122 * pseudomonas sp. 63000.0 1 PMID:31278898 -1.1.1.122 * saccharolobus solfataricus 149700.0 2 PMID:16849334 -1.1.1.122 * trinickia caryophylli 71000.0 1 PMID:40609 -1.1.1.123 * bemisia argentifolii 39000.0 3 PMID:10196734 -1.1.1.123 * clostridium pasteurianum 35900.0 1 PMID:33616697 -1.1.1.123 * corynebacterium sp. 33000.0 1 * -1.1.1.124 * erwinia sp. 50000.0 2 PMID:3178725 -1.1.1.124 * gluconobacter oxydans 100000.0 2 * -1.1.1.127 * pectobacterium carotovorum subsp. carotovorum 90000.0 2 PMID:27028675 -1.1.1.132 * ectocarpus siliculosus 70000.0 3 PMID:21454608 -1.1.1.132 * pseudomonas aeruginosa 290000.0 5 PMID:1370473;PMID:2470755;PMID:3025179;PMID:7521247 -1.1.1.132 * saccharina japonica 35200.0 2 PMID:26956020 -1.1.1.133 * acanthamoeba polyphaga mimivirus 47000.0 2 PMID:20538863 -1.1.1.133 * aggregatibacter actinomycetemcomitans 32400.0 2 PMID:10702238 -1.1.1.133 * arabidopsis thaliana 35500.0 2 PMID:15020741 -1.1.1.133 * saccharothrix syringae 59800.0 2 PMID:34819927 -1.1.1.133 * salmonella enterica 49500.0 8 PMID:10455186 -1.1.1.133 * streptococcus sp. 32000.0 2 PMID:26278404 -1.1.1.135 * homo sapiens 28000.0 1 PMID:12696021 -1.1.1.136 * bacillus cytotoxicus nvh 391-98 47000.0 1 PMID:20529859 -1.1.1.136 * escherichia coli 51500.0 2 PMID:22730467 -1.1.1.136 * pseudomonas aeruginosa 162000.0 3 PMID:15226302 -1.1.1.136 * salmonella enterica subsp. enterica serovar typhi 120500.0 2 PMID:16800641 -1.1.1.137 * lacticaseibacillus casei 115000.0 2 PMID:3104310 -1.1.1.138 * agaricus bisporus 130000.0 6 PMID:11320313;PMID:9835550 -1.1.1.138 * alternaria alternata 28610.0 1 PMID:17177674 -1.1.1.138 * aspergillus parasiticus 140000.0 2 PMID:7085559 -1.1.1.138 * cladosporium herbarum 114000.0 3 PMID:16608840;PMID:20420880 -1.1.1.138 * fusarium graminearum 110000.0 2 PMID:12453571 -1.1.1.138 * gluconobacter oxydans 100000.0 4 PMID:27338577 -1.1.1.138 * lactobacillus intermedius 170000.0 3 PMID:15059000 -1.1.1.138 * limosilactobacillus reuteri 75000.0 3 PMID:15630578 -1.1.1.138 * penicillium chrysogenum 160000.0 2 * -1.1.1.138 * starmerella magnoliae 142000.0 3 PMID:12790637;PMID:12902227 -1.1.1.138 * tuber borchii 163000.0 2 PMID:17317242 -1.1.1.14 * bacillus subtilis 153000.0 2 PMID:1460002;PMID:9143345 -1.1.1.14 * bos taurus 156000.0 2 PMID:1460002;PMID:9143345 -1.1.1.14 * cereibacter sphaeroides 61000.0 2 PMID:7551049 -1.1.1.14 * equus caballus 110000.0 2 * -1.1.1.14 * fragaria x ananassa 38800.0 1 * -1.1.1.14 * gluconobacter oxydans 800000.0 5 PMID:11866120;PMID:12686146;PMID:16232778 -1.1.1.14 * homo sapiens 155000.0 2 PMID:14965227 -1.1.1.14 * malus domestica 120000.0 2 * -1.1.1.14 * mammalia 155000.0 2 PMID:14965227 -1.1.1.14 * mus musculus 39000.0 1 PMID:18799757 -1.1.1.14 * ovis aries 155000.0 6 PMID:13914358;PMID:14965227;PMID:7032910 -1.1.1.14 * pseudomonas sp. 65800.0 2 * -1.1.1.14 * rattus norvegicus 155000.0 4 PMID:14965227;PMID:667078;PMID:7144570 -1.1.1.14 * scheffersomyces stipitis 63000.0 2 * -1.1.1.140 * clostridium pasteurianum 94000.0 1 PMID:4318899 -1.1.1.140 * escherichia coli 117000.0 2 PMID:6384188 -1.1.1.140 * haloarcula marismortui 41000.0 1 * -1.1.1.140 * pyrus pyrifolia 34900.0 1 * -1.1.1.141 * bos taurus 40000.0 1 PMID:4453620 -1.1.1.141 * homo sapiens 54000.0 12 PMID:1117007;PMID:18328086;PMID:18500342;PMID:2286636;PMID:2337593;PMID:2393668;PMID:23954207;PMID:241691;PMID:3954355;PMID:7132749;PMID:8086429;PMID:8508808 -1.1.1.141 * macaca fascicularis 28900.0 1 PMID:11872167 -1.1.1.141 * oryctolagus cuniculus 29000.0 1 PMID:18328086;PMID:3954355 -1.1.1.141 * sus scrofa 55000.0 2 PMID:2337593;PMID:2393668 -1.1.1.142 * trifolium incarnatum 34000.0 1 PMID:4389340 -1.1.1.143 * trifolium incarnatum 34000.0 1 PMID:4389340 -1.1.1.145 * bos taurus 41000.0 1 PMID:3867664 -1.1.1.145 * bufo gargarizans 42800.0 1 PMID:30170058 -1.1.1.145 * digitalis lanata 29000.0 2 PMID:10550629;PMID:17564944 -1.1.1.145 * homo sapiens 42000.0 5 PMID:11463578;PMID:15026177;PMID:18524572;PMID:18955108;PMID:20420909;PMID:22106846;PMID:22262841 -1.1.1.145 * macaca mulatta 41874.0 1 PMID:2050270 -1.1.1.145 * ovis aries 300000.0 2 PMID:4274151 -1.1.1.145 * rattus norvegicus 45000.0 1 PMID:12798361 -1.1.1.145 * sus scrofa 36000.0 3 PMID:7841933;PMID:8702847 -1.1.1.146 * bos taurus 32000.0 1 PMID:19009916;PMID:19109222 -1.1.1.146 * homo sapiens 67400.0 9 PMID:11841241;PMID:12604230;PMID:12604232;PMID:15033547;PMID:16263772;PMID:16343739;PMID:18327553;PMID:18573267;PMID:24055708;PMID:27025972 -1.1.1.146 * mus musculus 34000.0 2 PMID:11841241;PMID:12604230;PMID:12604232;PMID:15033547;PMID:16343739;PMID:19720048 -1.1.1.146 * oryctolagus cuniculus 35000.0 1 PMID:7836463 -1.1.1.146 * rattus norvegicus 51500.0 4 PMID:11796518;PMID:18573267;PMID:19009916;PMID:19109222;PMID:24815509;PMID:3139396 -1.1.1.146 * rattus sp. 34000.0 1 PMID:24815509;PMID:3139396 -1.1.1.146 * sus scrofa 32000.0 1 PMID:17709565 -1.1.1.148 * equus caballus 52500.0 2 PMID:6584179 -1.1.1.148 * eubacterium sp. 160000.0 2 PMID:8071614 -1.1.1.148 * oryctolagus cuniculus 39600.0 1 PMID:849262 -1.1.1.149 * [clostridium] scindens 160000.0 2 PMID:2722736 -1.1.1.149 * bifidobacterium adolescentis 130500.0 1 PMID:31209107 -1.1.1.149 * bos taurus 40000.0 3 PMID:21908655;PMID:3867809 -1.1.1.149 * homo sapiens 68000.0 5 PMID:11013348;PMID:4148413;PMID:6935192;PMID:7484385 -1.1.1.149 * macaca fascicularis 39000.0 3 PMID:21831350 -1.1.1.149 * rattus norvegicus 75100.0 6 PMID:10417353;PMID:1888758;PMID:6586205;PMID:8194472;PMID:8977402 -1.1.1.149 * sus scrofa 40000.0 6 PMID:24875897;PMID:2615363;PMID:4400473;PMID:945195 -1.1.1.149 * tetrahymena pyriformis 68000.0 2 PMID:7484385;PMID:8280099 -1.1.1.149 * tetrahymena thermophila 68000.0 2 PMID:6935192;PMID:7484385;PMID:8280099 -1.1.1.15 * bradyrhizobium japonicum 83200.0 3 PMID:27827356 -1.1.1.152 * comamonas testosteroni 47000.0 1 PMID:5365796 -1.1.1.153 * bombyx mori 29200.0 1 PMID:19246455 -1.1.1.153 * bos taurus 59000.0 2 PMID:8493908 -1.1.1.153 * chlorobaculum tepidum 55000.0 2 PMID:7052139 -1.1.1.153 * dictyostelium discoideum 32372.0 3 PMID:10987137 -1.1.1.153 * drosophila melanogaster 39000.0 2 * -1.1.1.153 * homo sapiens 56000.0 5 PMID:12414107;PMID:23640889;PMID:8304110 -1.1.1.153 * mus musculus 30000.0 1 PMID:12414107 -1.1.1.153 * musca domestica 51000.0 1 PMID:27704475 -1.1.1.153 * rattus norvegicus 56000.0 3 PMID:3296952;PMID:7052139 -1.1.1.156 * gluconobacter oxydans 30000.0 1 PMID:18685208 -1.1.1.156 * phycomyces blakesleeanus 39000.0 2 * -1.1.1.156 * schizosaccharomyces pombe 57000.0 3 PMID:2621446 -1.1.1.156 * trichoderma reesei 35660.0 1 PMID:16930134 -1.1.1.157 * clostridium kluyveri 220000.0 4 PMID:4405720;PMID:6149704 -1.1.1.159 * bacteroides fragilis 127000.0 4 PMID:14756531;PMID:236279 -1.1.1.159 * brevibacterium fuscum 104000.0 2 * -1.1.1.159 * comamonas testosteroni 27000.0 1 PMID:23972763 -1.1.1.159 * escherichia coli 120000.0 4 PMID:2007545;PMID:2186848;PMID:9722677 -1.1.1.159 * eubacterium sp. 110000.0 1 PMID:1856160 -1.1.1.159 * paraclostridium sordellii 30000.0 1 PMID:8050999 -1.1.1.159 * pseudomonas sp. 108000.0 2 * -1.1.1.16 * rhizobium leguminosarum 114000.0 2 PMID:24731824 -1.1.1.162 * bos taurus 90000.0 2 PMID:4152124;PMID:6292658 -1.1.1.162 * gallus gallus 96000.0 2 PMID:7358641 -1.1.1.168 * candida parapsilosis 41600.0 2 PMID:2644973 -1.1.1.168 * saccharomyces cerevisiae 27000.0 1 PMID:4603075 -1.1.1.168 * spinacia oleracea 36000.0 1 * -1.1.1.169 * escherichia coli 34000.0 7 PMID:10553653;PMID:10736170;PMID:11724562 -1.1.1.169 * salmonella enterica subsp. enterica serovar typhimurium 31100.0 2 PMID:11724562;PMID:9488683 -1.1.1.169 * stenotrophomonas maltophilia 160000.0 4 PMID:11724562;PMID:3042788 -1.1.1.169 * thermococcus kodakarensis 60000.0 2 PMID:23941541 -1.1.1.17 * acinetobacter baumannii 87000.0 1 PMID:29575790 -1.1.1.17 * acinetobacter baylyi 81300.0 1 PMID:23414076 -1.1.1.17 * aspergillus fumigatus 40000.0 1 PMID:18452897 -1.1.1.17 * aspergillus niger 40000.0 2 PMID:4019499;PMID:6384188;PMID:7030216 -1.1.1.17 * aspergillus parasiticus 40000.0 1 PMID:4019499;PMID:6384188;PMID:7030216 -1.1.1.17 * brochothrix thermosphacta 50000.0 1 * -1.1.1.17 * caloglossa continua 53000.0 1 PMID:12972650 -1.1.1.17 * cryptococcus neoformans 148000.0 2 PMID:11021946 -1.1.1.17 * ectocarpus siliculosus 60000.0 6 PMID:20981555;PMID:26232554 -1.1.1.17 * enterococcus faecalis 40000.0 1 PMID:1904856 -1.1.1.17 * escherichia coli 45500.0 3 PMID:3545182;PMID:4019499;PMID:6384188;PMID:7030216 -1.1.1.17 * klebsiella aerogenes 40000.0 1 PMID:14465816 -1.1.1.17 * klebsiella pneumoniae 42000.0 1 PMID:11164312 -1.1.1.17 * streptococcus mutans 45000.0 1 PMID:873604 -1.1.1.172 * homo sapiens 95000.0 1 PMID:185965 -1.1.1.173 * scheffersomyces stipitis 30000.0 2 PMID:18400031;PMID:18505728 -1.1.1.175 * arthrobacter sp. 62000.0 1 * -1.1.1.175 * haloferax mediterranei 89000.0 2 PMID:8925901 -1.1.1.175 * pseudomonas sp. 67000.0 1 * -1.1.1.176 * [clostridium] leptum 225000.0 1 PMID:23170 -1.1.1.176 * brevibacterium fuscum 110000.0 2 * -1.1.1.176 * clostridium sp. 108000.0 4 PMID:2007406 -1.1.1.176 * eggerthella lenta 125000.0 1 PMID:39496 -1.1.1.176 * eggerthella sp. cag:298 26355.0 1 PMID:29330189 -1.1.1.178 * homo sapiens 27000.0 1 PMID:18996107 -1.1.1.178 * pseudomonas putida 130000.0 1 PMID:4150713 -1.1.1.178 * rattus norvegicus 66000.0 2 PMID:7639524 -1.1.1.179 * bos taurus 48000.0 1 * -1.1.1.179 * canis lupus familiaris 48000.0 1 * -1.1.1.179 * haloarcula marismortui 175000.0 2 PMID:15342590 -1.1.1.179 * haloferax volcanii 165000.0 3 PMID:19584053 -1.1.1.179 * macaca fuscata 70000.0 2 PMID:11097839 -1.1.1.179 * paenarthrobacter nicotinovorans 47000.0 1 PMID:23063486 -1.1.1.179 * sus scrofa 62000.0 3 PMID:2327952 -1.1.1.179 * trichoderma reesei 42720.0 1 PMID:18031347 -1.1.1.18 * bacillus subtilis 160000.0 5 PMID:112095;PMID:1761221;PMID:18259059 -1.1.1.18 * galdieria sulphuraria 180000.0 3 * -1.1.1.18 * lacticaseibacillus casei 38330.0 1 PMID:25005103 -1.1.1.18 * sinorhizobium fredii 34648.0 1 PMID:11274120 -1.1.1.18 * sinorhizobium meliloti 35130.0 1 PMID:9802033 -1.1.1.181 * oryctolagus cuniculus 46000.0 1 PMID:6937465 -1.1.1.183 * backhousia citriodora 41000.0 2 PMID:21636906 -1.1.1.183 * carpoglyphus lactis 42800.0 1 PMID:18422649 -1.1.1.183 * citrus sp. 92000.0 1 * -1.1.1.183 * cymbopogon flexuosus 84000.0 1 * -1.1.1.183 * persicaria minor 120000.0 6 PMID:22878188 -1.1.1.183 * zingiber officinale 39590.0 1 * -1.1.1.184 * candida macedoniensis 48000.0 1 PMID:1567202 -1.1.1.184 * candida parapsilosis 135000.0 4 PMID:18566346;PMID:7764255 -1.1.1.184 * canis lupus familiaris 100000.0 3 PMID:12604222;PMID:17827741;PMID:25918240;PMID:9880795 -1.1.1.184 * cavia porcellus 115000.0 6 PMID:6439186;PMID:6753749 -1.1.1.184 * cricetulus griseus 38000.0 11 PMID:12604224;PMID:18983989 -1.1.1.184 * cylindrocarpon sclerotigenum 68000.0 2 PMID:12843676 -1.1.1.184 * gallus gallus 48000.0 5 PMID:1338044;PMID:22266778 -1.1.1.184 * gluconobacter oxydans 66100.0 4 PMID:20414648 -1.1.1.184 * homo sapiens 67400.0 8 PMID:1597188;PMID:16343739;PMID:17344335;PMID:18493841;PMID:19022938;PMID:25680283;PMID:7005231 -1.1.1.184 * kluyveromyces lactis 190000.0 1 PMID:12353647 -1.1.1.184 * kluyveromyces marxianus 37000.0 4 PMID:26223585 -1.1.1.184 * methanobacterium palustre 175000.0 2 PMID:1879431 -1.1.1.184 * mus musculus 90000.0 2 PMID:3085728 -1.1.1.184 * neurospora crassa 40000.0 3 PMID:22113019 -1.1.1.184 * oryctolagus cuniculus 110000.0 2 PMID:12604222;PMID:17827741;PMID:9880795 -1.1.1.184 * pichia kudriavzevii 46000.0 2 * -1.1.1.184 * rattus norvegicus 33000.0 2 PMID:2226449 -1.1.1.184 * rhodotorula glutinis 40000.0 2 PMID:15665471 -1.1.1.184 * scheffersomyces stipitis 35000.0 2 PMID:19125224;PMID:19574038 -1.1.1.184 * starmerella magnoliae 76000.0 3 PMID:10945260;PMID:9532783 -1.1.1.184 * sus scrofa 103000.0 9 PMID:12604222;PMID:1597188;PMID:17012807;PMID:1731616;PMID:17827741;PMID:18334214;PMID:22266778;PMID:9880795 -1.1.1.184 * thermotoga maritima 35032.0 4 PMID:23338701;PMID:26144229 -1.1.1.185 * gallus gallus 28000.0 1 PMID:7018582 -1.1.1.187 * pseudomonas sp. 70000.0 1 PMID:4398966 -1.1.1.188 * bos taurus 37000.0 11 PMID:12432932;PMID:12664595;PMID:1339268;PMID:1605628;PMID:1958196;PMID:2829166;PMID:3858278;PMID:9867836 -1.1.1.188 * homo sapiens 37000.0 6 PMID:10622721;PMID:12432932;PMID:16157291;PMID:19010934;PMID:25126080 -1.1.1.188 * mus musculus 35000.0 3 PMID:18006499;PMID:19010934 -1.1.1.188 * oryctolagus cuniculus 66000.0 1 PMID:7132748;PMID:7248317 -1.1.1.188 * ovis aries 17000.0 2 PMID:12432932 -1.1.1.188 * rattus norvegicus 36700.0 3 PMID:10986358;PMID:12432932 -1.1.1.188 * sus scrofa 36800.0 2 PMID:16223862;PMID:18006499 -1.1.1.188 * trypanosoma brucei 33000.0 1 PMID:11067881 -1.1.1.189 * bos taurus 45000.0 1 PMID:10477039 -1.1.1.189 * gallus gallus 55000.0 1 PMID:166995 -1.1.1.189 * homo sapiens 36000.0 6 PMID:12432932;PMID:1449827;PMID:1597188;PMID:3459656;PMID:6586494 -1.1.1.189 * oryctolagus cuniculus 37000.0 2 PMID:12432932;PMID:8529651 -1.1.1.189 * sus scrofa 35000.0 4 PMID:1449827;PMID:1597188 -1.1.1.19 * bos taurus 70000.0 2 PMID:8898089 -1.1.1.19 * homo sapiens 39000.0 2 PMID:8343612 -1.1.1.19 * mus musculus 35000.0 2 PMID:15991 -1.1.1.19 * rattus norvegicus 70000.0 2 PMID:8898089 -1.1.1.19 * sus scrofa 36700.0 2 PMID:6755181 -1.1.1.190 * cucumis sativus 33000.0 2 PMID:16661122;PMID:2607 -1.1.1.191 * brassica rapa subsp. pekinensis 32000.0 1 PMID:16661122 -1.1.1.191 * cucumis sativus 52000.0 3 PMID:16661122;PMID:2607 -1.1.1.192 * amycolatopsis methanolica 120000.0 2 PMID:1597190 -1.1.1.192 * geobacillus thermodenitrificans 380000.0 4 PMID:19383697 -1.1.1.192 * nostoc sp. 35000.0 1 PMID:12515465 -1.1.1.192 * pseudomonas putida 163000.0 2 * -1.1.1.192 * saccharomyces cerevisiae 150000.0 1 PMID:29090341 -1.1.1.193 * acinetobacter baumannii 58000.0 3 PMID:23722836 -1.1.1.193 * escherichia coli 37000.0 1 PMID:30756 -1.1.1.193 * streptomyces davaonensis 22000.0 1 PMID:17541777 -1.1.1.194 * glycine max 43000.0 1 PMID:1250 -1.1.1.194 * streptomyces sp. 150000.0 2 PMID:23500723 -1.1.1.195 * arabidopsis thaliana 44000.0 2 PMID:12805615 -1.1.1.195 * aralia cordata 72000.0 2 PMID:7763430 -1.1.1.195 * camellia sinensis 41710.0 3 PMID:23228629 -1.1.1.195 * cucumis melo 39620.0 5 PMID:25019207 -1.1.1.195 * eucalyptus gunnii 35790.0 1 PMID:9526508 -1.1.1.195 * forsythia suspensa 80000.0 1 * -1.1.1.195 * ginkgo biloba 38700.0 1 PMID:23143181 -1.1.1.195 * glycine max 69000.0 1 PMID:1250 -1.1.1.195 * hibiscus cannabinus 38660.0 1 * -1.1.1.195 * leucaena leucocephala 80000.0 6 PMID:21708267;PMID:24064207;PMID:24532464 -1.1.1.195 * petroselinum crispum 38570.0 1 PMID:9377488 -1.1.1.195 * phaseolus vulgaris 65000.0 3 PMID:3315665;PMID:7765663 -1.1.1.195 * pinus taeda 82000.0 2 PMID:16668801 -1.1.1.195 * plagiochasma appendiculatum 60000.0 5 PMID:23774375 -1.1.1.195 * populus tomentosa 40000.0 12 PMID:25096165 -1.1.1.195 * populus tremula x populus alba 43000.0 1 PMID:9684367 -1.1.1.195 * populus x canadensis 70000.0 2 PMID:6365550 -1.1.1.195 * sinopodophyllum hexandrum 42100.0 4 PMID:27387305 -1.1.1.195 * sorghum bicolor 38655.0 1 * -1.1.1.195 * streptomyces sp. 143000.0 2 PMID:21897026 -1.1.1.195 * triticum aestivum 45000.0 4 PMID:20400532;PMID:27899932 -1.1.1.195 * zinnia elegans 40000.0 2 * -1.1.1.196 * sus scrofa 62000.0 8 PMID:6958674;PMID:7132752;PMID:7354056 -1.1.1.197 * macaca fascicularis 31000.0 2 PMID:11872167 -1.1.1.198 * artemisia annua 31040.0 1 * -1.1.1.198 * lavandula x intermedia 27500.0 1 PMID:23058847 -1.1.1.198 * pseudomonas sp. 27600.0 1 PMID:27542933 -1.1.1.198 * salvia officinalis 124800.0 3 PMID:3310901;PMID:677891 -1.1.1.199 * evernia prunastri 450000.0 1 * -1.1.1.2 * acinetobacter sp. 160000.0 2 PMID:11097895;PMID:21515780;PMID:7030321 -1.1.1.2 * bos taurus 56000.0 8 PMID:6416297;PMID:6753832 -1.1.1.2 * canis lupus familiaris 40000.0 1 PMID:1907200 -1.1.1.2 * clostridium acetobutylicum 96000.0 1 PMID:8068002 -1.1.1.2 * drosophila melanogaster 38500.0 2 PMID:744352 -1.1.1.2 * entamoeba histolytica 130000.0 2 PMID:6284905 -1.1.1.2 * escherichia coli 96000.0 1 PMID:8068002 -1.1.1.2 * gallus sp. 39500.0 7 PMID:16919;PMID:4463942;PMID:6343086;PMID:6753936;PMID:744352 -1.1.1.2 * geobacillus thermodenitrificans 90000.0 1 PMID:19383697 -1.1.1.2 * homo sapiens 90000.0 20 PMID:11257547;PMID:16919;PMID:1901806;PMID:3890957;PMID:3922304;PMID:4463942;PMID:45199;PMID:6753936;PMID:7016111;PMID:744352;PMID:8916913 -1.1.1.2 * marinobacter nauticus vt8 57000.0 1 PMID:19270127 -1.1.1.2 * methanobacterium palustre 175000.0 1 PMID:8135516 -1.1.1.2 * mycobacterium sp. 68000.0 2 PMID:26923741 -1.1.1.2 * mycolicibacterium smegmatis 38000.0 2 PMID:11257547;PMID:1901806 -1.1.1.2 * paenarthrobacter aurescens 65000.0 1 PMID:27196926 -1.1.1.2 * pectobacterium atrosepticum 71000.0 3 PMID:11742541;PMID:24265029 -1.1.1.2 * pelophylax perezi 80000.0 2 PMID:10473548 -1.1.1.2 * platyrrhini 70000.0 1 PMID:17294170;PMID:4148240 -1.1.1.2 * pseudothermotoga hypogea 70000.0 2 PMID:11742541;PMID:17294170;PMID:4148240 -1.1.1.2 * pyrococcus furiosus 270000.0 7 PMID:11358525;PMID:18452026;PMID:9973342 -1.1.1.2 * rattus norvegicus 75000.0 8 PMID:235531;PMID:2500152;PMID:3084464;PMID:6416297;PMID:6798966;PMID:6814444;PMID:7016111;PMID:744352 -1.1.1.2 * saccharomyces cerevisiae 81000.0 8 PMID:11742541;PMID:16919;PMID:17294170;PMID:19577617;PMID:24265029;PMID:4463942;PMID:744352;PMID:9327572 -1.1.1.2 * sporobolomyces salmonicolor 32000.0 1 PMID:6416297 -1.1.1.2 * sus scrofa 43700.0 17 PMID:16919;PMID:235531;PMID:4146452;PMID:4402936;PMID:4463942;PMID:6814444;PMID:6989609;PMID:7016111;PMID:744352 -1.1.1.2 * synechocystis sp. 140000.0 4 PMID:19411329 -1.1.1.2 * thermoanaerobacter brockii 150000.0 2 PMID:11097895;PMID:21515780;PMID:7030321 -1.1.1.2 * thermoanaerobacter ethanolicus 184000.0 7 PMID:8068002 -1.1.1.2 * thermoanaerobacter pseudethanolicus 44000.0 1 PMID:26203301 -1.1.1.2 * thermococcus guaymasensis 135000.0 2 PMID:11097895;PMID:21515780;PMID:7030321 -1.1.1.2 * thermococcus hydrothermalis 197000.0 3 PMID:10491136 -1.1.1.2 * thermococcus litoralis 200000.0 2 PMID:8135516 -1.1.1.2 * thermococcus paralvinellae 46000.0 2 PMID:7642502 -1.1.1.2 * thermococcus sp. 182000.0 8 PMID:19115036;PMID:9209068;PMID:9952458 -1.1.1.2 * vigna radiata 36000.0 1 * -1.1.1.20 * rattus norvegicus 41000.0 2 PMID:6706910 -1.1.1.200 * malus domestica 68000.0 5 PMID:19799961 -1.1.1.200 * oryza sativa 39000.0 1 PMID:24817585 -1.1.1.200 * prunus persica 67000.0 1 PMID:28011870 -1.1.1.201 * blautia producta 82000.0 2 PMID:2752021;PMID:6954878 -1.1.1.201 * clostridium sp. 115000.0 1 PMID:2923864 -1.1.1.201 * collinsella aerofaciens 56100.0 3 PMID:21181147;PMID:6954878 -1.1.1.201 * oryctolagus cuniculus 34000.0 1 PMID:15276626 -1.1.1.202 * aquifex aeolicus 43000.0 1 PMID:20124718 -1.1.1.202 * citrobacter freundii 440000.0 6 PMID:22821086;PMID:26966462;PMID:7721705 -1.1.1.202 * clostridium butyricum 384200.0 2 PMID:10938419;PMID:26966462 -1.1.1.202 * clostridium pasteurianum 440000.0 1 PMID:9311132 -1.1.1.202 * klebsiella pneumoniae 446000.0 10 PMID:16230771;PMID:17329826;PMID:19011020;PMID:26966462;PMID:3553154 -1.1.1.202 * lentilactobacillus buchneri 355000.0 3 PMID:1622279 -1.1.1.202 * levilactobacillus brevis 355000.0 5 PMID:1622279;PMID:26961082;PMID:26966462 -1.1.1.202 * limosilactobacillus reuteri 180000.0 2 PMID:16348177 -1.1.1.202 * oenococcus oeni 74000.0 3 PMID:23385476 -1.1.1.202 * pantoea agglomerans 355000.0 2 PMID:26966462 -1.1.1.203 * agrobacterium tumefaciens 32000.0 1 PMID:19060141 -1.1.1.203 * pseudomonas putida kt2440 30000.0 1 PMID:19060141 -1.1.1.203 * pseudomonas syringae 59000.0 2 PMID:2471 -1.1.1.203 * pseudomonas syringae pv. tomato 30000.0 1 PMID:19060141 -1.1.1.205 * babesia gibsoni 57000.0 1 PMID:23142571 -1.1.1.205 * bacillus anthracis 52374.0 1 PMID:25572472 -1.1.1.205 * bacillus cereus 225000.0 3 PMID:10923792;PMID:2889474;PMID:9602532 -1.1.1.205 * bacillus subtilis 165000.0 1 PMID:4998714 -1.1.1.205 * borreliella burgdorferi 44000.0 2 PMID:9268334 -1.1.1.205 * burkholderia thailandensis 218000.0 1 PMID:25706619 -1.1.1.205 * campylobacter jejuni 52151.0 1 PMID:25572472 -1.1.1.205 * clostridium perfringens 52093.0 1 PMID:25572472 -1.1.1.205 * cricetulus griseus 56000.0 1 PMID:2902093 -1.1.1.205 * cryptococcus bacillisporus 58000.0 1 PMID:20823538 -1.1.1.205 * cryptococcus neoformans 58000.0 1 PMID:20823538 -1.1.1.205 * cryptosporidium parvum 38459.0 1 PMID:25945705 -1.1.1.205 * escherichia coli 249000.0 8 PMID:1103737;PMID:44191;PMID:4573200;PMID:6104455;PMID:7905423 -1.1.1.205 * homo sapiens 65000.0 9 PMID:17480004;PMID:17960124;PMID:1968764;PMID:2902093;PMID:7763314;PMID:7903306 -1.1.1.205 * klebsiella aerogenes 200000.0 4 PMID:1268228;PMID:4298224;PMID:5421955 -1.1.1.205 * klebsiella pneumoniae 440000.0 2 PMID:25706619 -1.1.1.205 * legionella pneumophila subsp. pneumophila 440000.0 1 PMID:25706619 -1.1.1.205 * leishmania donovani 204000.0 3 PMID:1671039;PMID:17173987 -1.1.1.205 * mus musculus 56000.0 1 PMID:10923792;PMID:2889474;PMID:9602532 -1.1.1.205 * mycobacterium tuberculosis 220000.0 2 * -1.1.1.205 * neisseria meningitidis 440000.0 1 PMID:25706619 -1.1.1.205 * pneumocystis carinii 50000.0 1 PMID:2857550;PMID:8980752 -1.1.1.205 * pyrococcus furiosus 52900.0 1 PMID:8890736 -1.1.1.205 * rattus norvegicus 245000.0 4 PMID:2897864;PMID:6140264 -1.1.1.205 * staphylococcus aureus 440000.0 2 PMID:25706619 -1.1.1.205 * streptococcus pyogenes 53000.0 3 PMID:10200156;PMID:10390598 -1.1.1.205 * streptococcus suis 52200.0 1 PMID:19744553 -1.1.1.205 * sus scrofa 57000.0 1 PMID:8102965 -1.1.1.205 * tritrichomonas suis 58000.0 2 PMID:10390598;PMID:6104455;PMID:7905423 -1.1.1.205 * trypanosoma brucei 420000.0 3 PMID:23369253 -1.1.1.205 * vibrio cholerae serotype o1 51943.0 1 PMID:25572472 -1.1.1.205 * vigna unguiculata 200000.0 2 PMID:2857550;PMID:8980752 -1.1.1.206 * anisodus acutangulus 29460.0 1 PMID:19751215 -1.1.1.206 * brugmansia arborea 29700.0 2 PMID:26988730 -1.1.1.206 * datura stramonium 56000.0 1 PMID:17402126 -1.1.1.206 * dendrobium nobile 60000.0 2 PMID:23104472 -1.1.1.206 * hyoscyamus niger 115000.0 2 PMID:16653065 -1.1.1.206 * pseudomonas sp. 58000.0 2 * -1.1.1.206 * withania coagulans 29340.0 1 PMID:23266822 -1.1.1.206 * withania somnifera 60000.0 1 PMID:24086372 -1.1.1.207 * mentha x piperita 35000.0 2 PMID:15728344;PMID:16662335 -1.1.1.208 * capsicum annuum 34700.0 2 PMID:18599651 -1.1.1.208 * mentha x piperita 35722.0 2 PMID:15728344;PMID:16662335 -1.1.1.209 * mus musculus 39000.0 3 PMID:16511129;PMID:2691507 -1.1.1.209 * oryctolagus cuniculus 41000.0 2 PMID:6955302 -1.1.1.21 * bos taurus 61000.0 14 PMID:10990;PMID:12183464;PMID:1815509;PMID:24019949;PMID:25528584;PMID:26215787;PMID:4216364;PMID:4458;PMID:6391552;PMID:6402510;PMID:6426471;PMID:7626055 -1.1.1.21 * cyberlindnera jadinii 69700.0 1 PMID:4381350 -1.1.1.21 * euonymus japonicus 67000.0 2 PMID:10681056;PMID:11306077;PMID:16664750 -1.1.1.21 * galdieria sulphuraria 80000.0 2 PMID:11306077;PMID:12223702 -1.1.1.21 * homo sapiens 39000.0 13 PMID:12183464;PMID:16337231;PMID:17083960;PMID:1815509;PMID:1901806;PMID:1905957;PMID:25528584;PMID:26215787;PMID:3922304;PMID:4402695;PMID:6426471;PMID:6814912;PMID:7484387;PMID:8039602 -1.1.1.21 * leishmania donovani 74000.0 2 PMID:18983902 -1.1.1.21 * oryctolagus cuniculus 40200.0 2 PMID:6402510 -1.1.1.21 * rattus norvegicus 36500.0 3 PMID:18845131;PMID:19342790;PMID:7961617 -1.1.1.21 * sungouiella intermedia 58000.0 2 PMID:10681056;PMID:11306077;PMID:16664750 -1.1.1.21 * xerophyta viscosa 36000.0 1 PMID:24939578 -1.1.1.21 * yamadazyma tenuis 80000.0 3 PMID:10681056;PMID:11306077;PMID:12223702;PMID:16664750;PMID:9307017 -1.1.1.21 * zea mays 35000.0 4 PMID:19056286 -1.1.1.210 * bos taurus 55000.0 1 PMID:6958329 -1.1.1.210 * ovis aries 36000.0 3 PMID:2605227;PMID:3483295 -1.1.1.211 * homo sapiens 230000.0 3 PMID:1550553 -1.1.1.211 * rattus norvegicus 460000.0 4 PMID:1730633;PMID:7150615 -1.1.1.212 * persea americana 168000.0 1 PMID:7075600 -1.1.1.213 * eggerthella sp. cag:298 26355.0 1 PMID:29330189 -1.1.1.213 * eubacterium sp. 27000.0 1 PMID:7766153 -1.1.1.213 * mesocricetus auratus 35000.0 1 PMID:2317205 -1.1.1.213 * pseudomonas sp. 26000.0 1 PMID:16905772 -1.1.1.213 * rattus norvegicus 75000.0 12 PMID:10625484;PMID:16113996;PMID:17475203;PMID:18291663;PMID:1840601;PMID:18574251;PMID:6435601;PMID:9029723 -1.1.1.214 * candida parapsilosis 38000.0 3 PMID:14593510;PMID:23852710 -1.1.1.214 * spinacia oleracea 36000.0 1 * -1.1.1.215 * acetobacter ascendens 120000.0 2 * -1.1.1.215 * acetobacter pasteurianus 120000.0 2 * -1.1.1.215 * brevibacterium ketosoreductum 72000.0 2 PMID:9501529 -1.1.1.215 * campylobacter jejuni 63700.0 2 PMID:18284594 -1.1.1.215 * escherichia coli 74000.0 2 PMID:9811658 -1.1.1.215 * gluconacetobacter liquefaciens 120000.0 3 * -1.1.1.215 * gluconobacter frateurii 65000.0 3 PMID:17720837 -1.1.1.215 * gluconobacter oxydans 200000.0 2 PMID:20676631 -1.1.1.216 * aedes aegypti 60000.0 2 PMID:19940247 -1.1.1.216 * ipomoea batatas 90000.0 2 * -1.1.1.216 * persicaria minor 130000.0 3 PMID:26600471 -1.1.1.217 * saccharomyces cerevisiae 32000.0 2 * -1.1.1.218 * cavia porcellus 29000.0 1 PMID:2580834 -1.1.1.218 * mesocricetus auratus 38000.0 2 PMID:10666297 -1.1.1.218 * oryctolagus cuniculus 38000.0 3 PMID:9143356 -1.1.1.218 * pseudomonas putida 310000.0 5 PMID:10642529;PMID:10666297 -1.1.1.219 * brassica rapa subsp. pekinensis 40450.0 11 PMID:25108127 -1.1.1.219 * camellia sinensis 41000.0 4 * -1.1.1.219 * citrus sinensis 38010.0 1 PMID:16524606 -1.1.1.219 * cryptomeria japonica 133000.0 1 * -1.1.1.219 * komagataella phaffii 41400.0 2 PMID:27123855 -1.1.1.219 * lotus japonicus 40300.0 6 PMID:16087700 -1.1.1.219 * saussurea medusa 38600.0 1 PMID:21701830 -1.1.1.22 * bos taurus 305000.0 3 PMID:3099833;PMID:7920253 -1.1.1.22 * burkholderia cenocepacia j2315 52100.0 3 PMID:19383677 -1.1.1.22 * burkholderia cepacia 52600.0 1 PMID:20208157 -1.1.1.22 * capra hircus 300000.0 2 PMID:4340122 -1.1.1.22 * escherichia coli 86000.0 4 PMID:4568129;PMID:7635844;PMID:793622 -1.1.1.22 * glycine max 55000.0 1 * -1.1.1.22 * halobacterium salinarum 550000.0 3 PMID:27527219 -1.1.1.22 * haloferax volcanii 550000.0 2 PMID:27527219 -1.1.1.22 * homo sapiens 345000.0 6 PMID:15044486;PMID:15247292;PMID:17927902;PMID:24145036 -1.1.1.22 * nicotiana tabacum 43000.0 1 PMID:15821883 -1.1.1.22 * phaseolus vulgaris 40000.0 1 PMID:8546701 -1.1.1.22 * phoma herbarum 60000.0 2 * -1.1.1.22 * populus tremula x populus tremuloides 53100.0 1 PMID:12031484 -1.1.1.22 * pseudomonas aeruginosa 117000.0 4 PMID:17442666 -1.1.1.22 * pyrobaculum islandicum 50000.0 2 PMID:21979093 -1.1.1.22 * rattus norvegicus 300000.0 2 PMID:4340122 -1.1.1.22 * saccharum spp. 52000.0 1 PMID:12413493 -1.1.1.22 * sphingomonas elodea 48500.0 3 PMID:17668199;PMID:23137539 -1.1.1.22 * sphingomonas sanxanigenens 48200.0 1 PMID:25842901 -1.1.1.22 * streptococcus pyogenes 52000.0 4 PMID:22961854;PMID:9013585 -1.1.1.220 * rattus norvegicus 37000.0 1 PMID:2656673 -1.1.1.223 * mentha x piperita 66000.0 1 PMID:3885858 -1.1.1.224 * apium graveolens 58000.0 4 PMID:16668806;PMID:9112783 -1.1.1.224 * phelipanche ramosa 37000.0 3 PMID:12010466 -1.1.1.224 * striga hermonthica 33000.0 1 * -1.1.1.226 * sinomonas cyclohexanicum 53600.0 2 PMID:3292236 -1.1.1.227 * lavandula x intermedia 27500.0 1 PMID:23058847 -1.1.1.227 * tanacetum vulgare 70000.0 1 PMID:3310901 -1.1.1.228 * salvia officinalis 92000.0 1 PMID:3310901 -1.1.1.228 * tanacetum vulgare 70000.0 1 PMID:3310901 -1.1.1.229 * torulaspora delbrueckii 63000.0 2 * -1.1.1.23 * [bacillus] caldolyticus 29000.0 1 PMID:921748 -1.1.1.23 * bacillus subtilis 29000.0 1 PMID:921748 -1.1.1.23 * brassica oleracea 103000.0 4 PMID:1586152;PMID:1989490;PMID:7042909 -1.1.1.23 * brucella sp. 47000.0 1 * -1.1.1.23 * brucella suis 49000.0 1 * -1.1.1.23 * burkholderia pseudomallei 47000.0 1 * -1.1.1.23 * escherichia coli 91000.0 3 PMID:1586152;PMID:1989490;PMID:7042909 -1.1.1.23 * geobacillus stearothermophilus 29000.0 1 PMID:921748 -1.1.1.23 * geotrichum candidum 47000.0 1 * -1.1.1.23 * mycobacterium tuberculosis 101800.0 4 PMID:21672513 -1.1.1.23 * salmonella enterica subsp. enterica serovar typhimurium 90000.0 3 PMID:391222 -1.1.1.23 * sporosarcina psychrophila 29000.0 1 PMID:921748 -1.1.1.230 * [clostridium] innocuum 53000.0 2 PMID:3164718 -1.1.1.231 * cricetulus griseus 34000.0 1 PMID:11306100 -1.1.1.231 * macaca fascicularis 31000.0 1 PMID:11872167 -1.1.1.231 * oryctolagus cuniculus 62000.0 3 PMID:6182444;PMID:7061415 -1.1.1.233 * flavobacterium sp. 120000.0 3 PMID:3240988 -1.1.1.234 * sorghum bicolor 40000.0 2 PMID:26994288 -1.1.1.236 * anisodus acutangulus 28290.0 1 PMID:19751215 -1.1.1.236 * atropa belladonna 78500.0 3 PMID:16426652;PMID:7765621 -1.1.1.236 * datura stramonium 77700.0 5 PMID:16426652;PMID:7765621 -1.1.1.236 * dendrobium nobile 29420.0 1 * -1.1.1.236 * hyoscyamus niger 103000.0 7 PMID:10635114;PMID:16426652 -1.1.1.236 * solanum dulcamara 29000.0 1 PMID:18214963 -1.1.1.236 * solanum tuberosum 28400.0 2 PMID:16426652;PMID:16845528 -1.1.1.237 * coleus scutellarioides 68000.0 5 PMID:15284489;PMID:20445235 -1.1.1.237 * perilla frutescens 34422.0 1 * -1.1.1.237 * wickerhamia fluorescens 75000.0 3 PMID:21672638 -1.1.1.238 * clostridium paraputrificum 126000.0 1 PMID:3167086 -1.1.1.239 * alcaligenes sp. 86000.0 3 PMID:2997177 -1.1.1.239 * cavia porcellus 176000.0 1 PMID:859320 -1.1.1.239 * ilyonectria destructans 59000.0 2 PMID:2844744 -1.1.1.239 * mesocricetus auratus 37000.0 1 PMID:26002966 -1.1.1.239 * streptomyces exfoliatus 130000.0 1 * -1.1.1.24 * aspergillus niger 23000.0 1 PMID:4342549 -1.1.1.24 * daucus carota 110000.0 2 * -1.1.1.24 * neurospora crassa 42000.0 2 PMID:148913 -1.1.1.24 * pinus taeda 35000.0 1 * -1.1.1.24 * vigna radiata var. radiata 160000.0 2 * -1.1.1.240 * pseudomonas sp. 124000.0 2 * -1.1.1.243 * rhodococcus erythropolis 120000.0 2 PMID:10473585 -1.1.1.244 * bacillus methanolicus 430000.0 4 PMID:12089158;PMID:12351635;PMID:2280706;PMID:2673121 -1.1.1.244 * lysinibacillus xylanilyticus 420000.0 1 PMID:32117944 -1.1.1.245 * nocardia sp. 145000.0 1 * -1.1.1.245 * rhodococcus sp. (in: high g+c gram-positive bacteria) 60000.0 2 * -1.1.1.245 * saccharolobus solfataricus 150000.0 2 PMID:16101287 -1.1.1.247 * papaver somniferum 35000.0 1 PMID:7588736 -1.1.1.248 * papaver bracteatum 36600.0 2 PMID:17337529 -1.1.1.248 * papaver somniferum 52000.0 4 PMID:16968522 -1.1.1.25 * archaeoglobus fulgidus 60000.0 5 PMID:15336409;PMID:22139165 -1.1.1.25 * bacillus anthracis 30160.0 1 PMID:19043750 -1.1.1.25 * capsicum annuum 67000.0 1 * -1.1.1.25 * corynebacterium glutamicum 30000.0 2 PMID:23306642 -1.1.1.25 * cucumis sativus 45000.0 1 * -1.1.1.25 * escherichia coli 32000.0 4 PMID:10739937;PMID:3883995 -1.1.1.25 * euterpe oleracea 50000.0 1 * -1.1.1.25 * gluconobacter oxydans 60000.0 3 PMID:17090918 -1.1.1.25 * lathyrus oleraceus 57000.0 1 PMID:13686342 -1.1.1.25 * methanocaldococcus jannaschii 31691.0 2 PMID:12906831 -1.1.1.25 * mycobacterium tuberculosis 58370.0 7 PMID:12356471;PMID:16298142;PMID:19463851 -1.1.1.25 * physcomitrium patens 48000.0 1 PMID:687649 -1.1.1.25 * solanum lycopersicum 73000.0 1 * -1.1.1.25 * staphylococcus aureus 29000.0 1 PMID:24727420 -1.1.1.25 * staphylococcus epidermidis rp62a 31010.0 2 PMID:19215302 -1.1.1.25 * thermotoga maritima 30000.0 2 PMID:21795804 -1.1.1.25 * vigna mungo 57000.0 1 PMID:620036 -1.1.1.250 * candida tropicalis 31000.0 1 PMID:8250887 -1.1.1.250 * thermotoga maritima 320000.0 2 PMID:21347726 -1.1.1.251 * escherichia coli 37422.0 1 PMID:7772602;PMID:8955298 -1.1.1.252 * pyricularia grisea 120400.0 3 PMID:8112349 -1.1.1.254 * agrobacterium sp. 88000.0 4 PMID:9003445 -1.1.1.254 * agrobacterium sp. 525a 86000.0 2 PMID:9214773 -1.1.1.255 * apium graveolens 43000.0 4 PMID:19727802;PMID:7630943;PMID:9414553 -1.1.1.257 * comamonas testosteroni 102000.0 2 PMID:9006050 -1.1.1.26 * homo sapiens 40000.0 2 PMID:10524214 -1.1.1.26 * pseudomonas fluorescens 180000.0 1 PMID:236457 -1.1.1.26 * rhizobium etli 77200.0 3 PMID:17693143 -1.1.1.26 * spinacia oleracea 125000.0 5 PMID:16653027 -1.1.1.26 * thermococcus litoralis 76000.0 3 PMID:11532010 -1.1.1.261 * aeropyrum pernix 72400.0 2 PMID:11846799 -1.1.1.261 * methanocaldococcus jannaschii 44000.0 2 PMID:26175150 -1.1.1.261 * methanothermobacter thermautotrophicus 302000.0 2 PMID:9348086;PMID:9419225 -1.1.1.261 * sulfurisphaera tokodaii 35000.0 1 PMID:16428851 -1.1.1.263 * ensifer adhaerens 40000.0 3 PMID:16461673 -1.1.1.263 * mus musculus 34000.0 1 PMID:18323634 -1.1.1.263 * sus scrofa 38000.0 2 PMID:9504428 -1.1.1.264 * gluconobacter oxydans 110000.0 2 * -1.1.1.265 * saccharomyces cerevisiae 37000.0 1 PMID:9327572 -1.1.1.267 * aquilaria sinensis 51859.0 1 PMID:26174671 -1.1.1.267 * camptotheca acuminata 51400.0 1 PMID:17257708 -1.1.1.267 * escherichia coli 150000.0 2 PMID:9707569 -1.1.1.267 * francisella tularensis 94000.0 2 PMID:20011597 -1.1.1.267 * glycine max 76400.0 1 PMID:18437529 -1.1.1.267 * hevea brasiliensis 51000.0 4 PMID:17936410;PMID:18997428 -1.1.1.267 * mentha x piperita 43500.0 1 PMID:10222052 -1.1.1.267 * mycobacterium tuberculosis 45000.0 2 PMID:16321944;PMID:17491006 -1.1.1.267 * plasmodium falciparum 63000.0 2 PMID:11162369;PMID:20208174 -1.1.1.267 * plectranthus barbatus 54000.0 1 * -1.1.1.267 * rauvolfia verticillata 51300.0 1 PMID:17542498 -1.1.1.267 * salvia miltiorrhiza 51600.0 1 PMID:18302535 -1.1.1.267 * synechocystis sp. 75000.0 2 PMID:14580998 -1.1.1.267 * toxoplasma gondii 45000.0 1 PMID:23428849 -1.1.1.267 * yersinia pestis 43100.0 1 PMID:25171339 -1.1.1.267 * zymomonas mobilis 108000.0 2 PMID:11004410 -1.1.1.268 * xanthobacter sp. 63900.0 1 PMID:11851420 -1.1.1.27 * acinetobacter calcoaceticus 670000.0 2 * -1.1.1.27 * agama stellio stellio 36000.0 1 PMID:12139477 -1.1.1.27 * aggregatibacter actinomycetemcomitans 42000.0 1 PMID:19924225 -1.1.1.27 * cryptosporidium parvum 134000.0 2 PMID:14694073 -1.1.1.27 * cupriavidus necator 67000.0 2 PMID:6825697 -1.1.1.27 * fundulus heteroclitus 187000.0 3 PMID:6693386 -1.1.1.27 * homo sapiens 35000.0 1 PMID:1996957 -1.1.1.27 * ipomoea batatas 150000.0 1 PMID:19425 -1.1.1.27 * lacticaseibacillus casei 135000.0 3 PMID:823016 -1.1.1.27 * lactobacillus helveticus 138000.0 1 PMID:9212432 -1.1.1.27 * lactobacillus sp. 78000.0 2 PMID:18333614 -1.1.1.27 * lactococcus cremoris 140000.0 1 PMID:7144579 -1.1.1.27 * molinema dessetae 113000.0 2 PMID:8897500 -1.1.1.27 * oryctolagus cuniculus 140000.0 1 * -1.1.1.27 * saduria entomon 140000.0 2 PMID:11007175;PMID:242300;PMID:710448 -1.1.1.27 * staphylococcus aureus 39000.0 2 PMID:19851020 -1.1.1.27 * staphylococcus epidermidis 130000.0 3 PMID:11007175;PMID:242300;PMID:710448 -1.1.1.27 * streptococcus uberis 144000.0 2 PMID:3790089 -1.1.1.27 * sus scrofa 35000.0 1 PMID:28564593 -1.1.1.27 * taenia asiatica 35200.0 1 PMID:18836746 -1.1.1.27 * thermoanaerobacter ethanolicus 134000.0 2 PMID:1669451 -1.1.1.27 * thermotoga maritima 280900.0 5 PMID:8732758 -1.1.1.27 * toxoplasma gondii 39900.0 2 PMID:19422070 -1.1.1.270 * eggerthella sp. cag:298 31590.0 1 PMID:29330189 -1.1.1.270 * oryctolagus cuniculus 35000.0 1 PMID:22874434 -1.1.1.271 * arabidopsis thaliana 35500.0 2 PMID:10758496;PMID:11737200;PMID:16650000 -1.1.1.271 * caenorhabditis elegans 35000.0 1 PMID:10758496;PMID:11737200;PMID:16650000 -1.1.1.271 * drosophila melanogaster 35000.0 1 PMID:10758496;PMID:11737200;PMID:16650000 -1.1.1.271 * escherichia coli 40000.0 3 PMID:11021971;PMID:11030750;PMID:9817848 -1.1.1.271 * helicobacter pylori 35000.0 1 PMID:10758496;PMID:11737200;PMID:16650000 -1.1.1.271 * mortierella alpina 40000.0 1 PMID:20035716 -1.1.1.271 * sus scrofa 63100.0 2 PMID:3338988 -1.1.1.272 * haloferax mediterranei 111000.0 4 PMID:17049749 -1.1.1.273 * rauvolfia serpentina 42000.0 1 * -1.1.1.274 * corynebacterium sp. 35000.0 6 PMID:14718658;PMID:3597405 -1.1.1.274 * escherichia coli 31800.0 3 PMID:10427017;PMID:11934293 -1.1.1.276 * agrobacterium tumefaciens 100000.0 1 PMID:9028042 -1.1.1.276 * escherichia coli 105000.0 2 PMID:12535615 -1.1.1.276 * saccharomyces cerevisiae 110000.0 2 PMID:12535615 -1.1.1.279 * saccharomyces cerevisiae 800000.0 3 PMID:3280313 -1.1.1.28 * aeropyrum pernix 61000.0 2 PMID:22102248 -1.1.1.28 * cerastoderma edule 70000.0 2 * -1.1.1.28 * cornu aspersum 140000.0 2 PMID:11944 -1.1.1.28 * escherichia coli 330000.0 3 PMID:25401076 -1.1.1.28 * eubacterium limosum 145000.0 1 PMID:236451 -1.1.1.28 * fusobacterium nucleatum subsp. nucleatum 160000.0 2 PMID:25401076 -1.1.1.28 * globisporangium debaryanum 115000.0 2 PMID:1128267 -1.1.1.28 * lactobacillus delbrueckii subsp. bulgaricus 75000.0 2 PMID:1569100;PMID:1610363;PMID:2044942 -1.1.1.28 * leuconostoc mesenteroides subsp. cremoris 40000.0 1 PMID:7569323 -1.1.1.28 * limulus polyphemus 80000.0 2 PMID:1128269;PMID:4348013 -1.1.1.28 * neisseria meningitidis 70000.0 1 PMID:8407815 -1.1.1.28 * pediococcus acidilactici 37000.0 1 PMID:22261863 -1.1.1.28 * pediococcus pentosaceus 37203.0 1 PMID:22484960 -1.1.1.28 * pseudomonas aeruginosa 120000.0 2 PMID:25401076 -1.1.1.28 * rhodopseudomonas palustris 235000.0 2 PMID:15056881 -1.1.1.28 * staphylococcus sp. 64000.0 2 PMID:16233312 -1.1.1.28 * treponema pallidum 78100.0 1 PMID:32963009 -1.1.1.280 * klebsiella pneumoniae 31000.0 2 * -1.1.1.280 * saccharomyces cerevisiae 50000.0 2 PMID:3280313 -1.1.1.281 * aneurinibacillus thermoaerophilus 38100.0 1 PMID:11096116 -1.1.1.281 * pseudomonas aeruginosa 34000.0 3 PMID:11856318 -1.1.1.282 * corynebacterium glutamicum 60000.0 2 PMID:23306642 -1.1.1.282 * escherichia coli 64000.0 3 PMID:12637497;PMID:15596430 -1.1.1.282 * neurospora crassa 41000.0 1 PMID:148913 -1.1.1.282 * pinus taeda 53000.0 2 * -1.1.1.282 * rhodococcus rhodochrous 44000.0 2 * -1.1.1.283 * aspergillus niger 38000.0 3 PMID:3276516 -1.1.1.283 * cyberlindnera mrakii 34000.0 1 * -1.1.1.283 * kluyveromyces marxianus 37000.0 4 PMID:26223585 -1.1.1.283 * saccharomyces cerevisiae 43000.0 1 PMID:3896793 -1.1.1.284 * [candida] boidinii 82000.0 4 PMID:10213000;PMID:1248477;PMID:2177826;PMID:23274177;PMID:26869606;PMID:6292667 -1.1.1.284 * agaricus bisporus 40000.0 1 PMID:14960302 -1.1.1.284 * arabidopsis thaliana 40000.0 1 PMID:18326829 -1.1.1.284 * aspergillus nidulans 75000.0 2 PMID:1248477;PMID:23274177;PMID:26869606;PMID:6292667 -1.1.1.284 * bos taurus 78000.0 3 PMID:2793862;PMID:3771532;PMID:6830251 -1.1.1.284 * brassica oleracea var. botrytis 41500.0 1 PMID:27940345 -1.1.1.284 * cereibacter sphaeroides 80000.0 1 PMID:8631716 -1.1.1.284 * chlamydomonas reinhardtii 96000.0 1 PMID:33316743 -1.1.1.284 * helicobacter pylori 52000.0 2 PMID:25132107 -1.1.1.284 * homo sapiens 90000.0 3 PMID:19011746;PMID:4332837;PMID:4373474 -1.1.1.284 * komagataella pastoris 84000.0 3 PMID:3771532;PMID:6830251 -1.1.1.284 * lactuca sativa 41300.0 1 PMID:27940345 -1.1.1.284 * lathyrus oleraceus 82300.0 2 PMID:574372 -1.1.1.284 * ogataea angusta 40000.0 1 PMID:17565589 -1.1.1.284 * paecilomyces variotii 41000.0 1 PMID:25398285 -1.1.1.284 * pseudomonas putida 72000.0 2 PMID:10213000 -1.1.1.284 * rattus norvegicus 110000.0 1 PMID:4332837 -1.1.1.284 * saccharomyces cerevisiae 80000.0 1 PMID:10608852 -1.1.1.284 * schwanniomyces vanrijiae 72000.0 2 PMID:1248477;PMID:23274177;PMID:26869606;PMID:6292667 -1.1.1.284 * solanum lycopersicum 81090.0 2 PMID:1248477;PMID:23274177;PMID:26869606;PMID:6292667 -1.1.1.284 * staphylococcus aureus 21000.0 1 PMID:19286809 -1.1.1.284 * zea mays 82000.0 2 PMID:10213000;PMID:2177826 -1.1.1.286 * deinococcus radiodurans 154000.0 3 PMID:16139794 -1.1.1.287 * gluconobacter oxydans 140000.0 5 PMID:16165327;PMID:19629658 -1.1.1.288 * oryza sativa 29601.0 1 PMID:25014258 -1.1.1.289 * candida albicans 124000.0 2 PMID:16134116 -1.1.1.289 * gluconobacter frateurii 87000.0 3 PMID:17468249 -1.1.1.289 * gluconobacter oxydans 60000.0 4 * -1.1.1.29 * arabidopsis thaliana 63500.0 2 PMID:23860243 -1.1.1.29 * homo sapiens 37000.0 1 PMID:23599041 -1.1.1.29 * hyphomicrobium methylovorum 70000.0 2 PMID:2114287;PMID:8759789 -1.1.1.29 * methylorubrum extorquens 71000.0 2 PMID:1657886 -1.1.1.29 * petroselinum crispum 90000.0 2 PMID:9116490 -1.1.1.290 * pseudomonas aeruginosa 83000.0 1 PMID:16511285 -1.1.1.291 * eubacterium barkeri 32000.0 1 PMID:16894175 -1.1.1.292 * ensifer adhaerens 40000.0 3 PMID:16461673 -1.1.1.298 * bacillus cereus 32000.0 2 PMID:19517068 -1.1.1.298 * chloroflexus aurantiacus 300000.0 2 PMID:11948153 -1.1.1.298 * metallosphaera sedula 105000.0 2 PMID:19684143 -1.1.1.299 * flavobacterium frigidimaris 123000.0 2 PMID:16306697 -1.1.1.299 * ignicoccus islandicus 133000.0 2 PMID:31301348 -1.1.1.299 * methanothermobacter thermautotrophicus 36700.0 2 PMID:9639601 -1.1.1.3 * arabidopsis thaliana 470000.0 3 PMID:11812230;PMID:12435751 -1.1.1.3 * bacillus subtilis 221000.0 1 PMID:33046675 -1.1.1.3 * glycine max 70000.0 3 PMID:19897476 -1.1.1.3 * hordeum vulgare 174000.0 2 PMID:24301152 -1.1.1.3 * lathyrus oleraceus 174000.0 3 PMID:24301152 -1.1.1.3 * pyrococcus horikoshii 92000.0 2 PMID:26154028 -1.1.1.3 * rhodospirillum rubrum 220000.0 3 PMID:414912 -1.1.1.3 * ricinus communis 280000.0 2 * -1.1.1.3 * saccharomyces cerevisiae 81000.0 2 PMID:1897932 -1.1.1.3 * spinacia oleracea 220000.0 2 PMID:7549965 -1.1.1.3 * thermotoga maritima 450000.0 1 PMID:30175674 -1.1.1.3 * triticum aestivum 290000.0 2 * -1.1.1.3 * zea mays 190000.0 6 PMID:3083775;PMID:762132 -1.1.1.30 * acidovorax sp. 110000.0 2 PMID:16233594;PMID:16935252 -1.1.1.30 * bos taurus 119000.0 5 PMID:3355176;PMID:3986202;PMID:6822516 -1.1.1.30 * camelus dromedarius 67000.0 1 PMID:11742753 -1.1.1.30 * cereibacter sphaeroides 89000.0 2 PMID:6981412 -1.1.1.30 * homo sapiens 38000.0 2 PMID:1639787 -1.1.1.30 * legionella pneumophila subsp. pneumophila 32000.0 2 PMID:25556866 -1.1.1.30 * paracoccus denitrificans 132000.0 5 PMID:20052585;PMID:24271169 -1.1.1.30 * pseudomonas aeruginosa 120000.0 1 PMID:20052585;PMID:24271169 -1.1.1.30 * pseudomonas fragi 27000.0 1 PMID:16325199 -1.1.1.30 * ralstonia pickettii 110000.0 5 PMID:16233594;PMID:16935252;PMID:19219638 -1.1.1.30 * rattus norvegicus 31000.0 2 PMID:3355176 -1.1.1.30 * staphylococcus xylosus 140000.0 3 PMID:7526614 -1.1.1.30 * zoogloea ramigera i-16-m 112000.0 2 PMID:7240131 -1.1.1.300 * homo sapiens 365000.0 4 PMID:14674758;PMID:15865448;PMID:17230527 -1.1.1.300 * oryctolagus cuniculus 60000.0 4 PMID:17534402 -1.1.1.301 * enterococcus avium 160000.0 2 PMID:12467497 -1.1.1.302 * aquifex aeolicus 50600.0 2 PMID:18671734 -1.1.1.302 * methanocaldococcus jannaschii 50000.0 3 PMID:16730025 -1.1.1.302 * nakaseomyces glabratus 57800.0 2 PMID:18671734 -1.1.1.303 * saccharomyces cerevisiae 140000.0 2 PMID:2222122 -1.1.1.304 * bacillus licheniformis 125000.0 2 PMID:26494135 -1.1.1.304 * geobacillus stearothermophilus 49000.0 2 PMID:8879540 -1.1.1.304 * klebsiella aerogenes 61000.0 2 PMID:2040298 -1.1.1.304 * klebsiella pneumoniae 96000.0 2 * -1.1.1.304 * mycobacterium sp. 150000.0 2 PMID:25082080 -1.1.1.304 * paenibacillus polymyxa 118000.0 2 PMID:23701367 -1.1.1.304 * rhodococcus erythropolis 26864.0 1 PMID:23568047 -1.1.1.304 * staphylococcus aureus 68000.0 1 PMID:3041963 -1.1.1.305 * ralstonia solanacearum 120000.0 1 PMID:20118241 -1.1.1.306 * amycolatopsis methanolica 120000.0 2 PMID:1597190 -1.1.1.306 * mycolicibacterium smegmatis 38263.0 1 PMID:12809551 -1.1.1.307 * candida tropicalis 37100.0 1 PMID:19557353 -1.1.1.307 * neurospora crassa 53000.0 2 PMID:15746370 -1.1.1.307 * rasamsonia emersonii 40000.0 2 PMID:20093741 -1.1.1.307 * scheffersomyces stipitis 65000.0 3 PMID:19330484;PMID:3921014 -1.1.1.307 * sungouiella intermedia 58000.0 1 PMID:10681056 -1.1.1.307 * yamadazyma tenuis 48000.0 2 PMID:9307017 -1.1.1.308 * cupriavidus pinatubonensis 75000.0 3 PMID:20150239 -1.1.1.31 * arabidopsis thaliana 150000.0 2 PMID:28705827 -1.1.1.31 * bacillus cereus 65000.0 3 PMID:19517068;PMID:27120461 -1.1.1.31 * diutina rugosa 80000.0 2 * -1.1.1.31 * mycobacterium tuberculosis 66000.0 1 PMID:29959185 -1.1.1.31 * oryctolagus cuniculus 74000.0 2 PMID:3335502 -1.1.1.31 * pseudomonas denitrificans (nom. rej.) 30000.0 2 PMID:23658760 -1.1.1.31 * pseudomonas putida 120000.0 4 PMID:12729017;PMID:8988636 -1.1.1.310 * chromohalobacter israelensis 61000.0 2 PMID:20007648 -1.1.1.311 * azoarcus sp. 93000.0 4 PMID:11479712;PMID:16388583 -1.1.1.312 * phytopseudomonas straminea 67000.0 2 PMID:11073908;PMID:15277747;PMID:26671 -1.1.1.312 * sphingomonas paucimobilis 67000.0 2 PMID:11073908;PMID:15277747;PMID:26671 -1.1.1.313 * chromohalobacter israelensis 27100.0 2 PMID:20133363 -1.1.1.313 * klebsiella oxytoca 101000.0 1 PMID:30718306 -1.1.1.315 * bos taurus 32000.0 2 PMID:11274198;PMID:7836368 -1.1.1.315 * homo sapiens 60000.0 5 PMID:11675386;PMID:12407145;PMID:18502750 -1.1.1.316 * arabidopsis thaliana 87500.0 4 PMID:12047629 -1.1.1.316 * lathyrus oleraceus 156000.0 3 PMID:12047629 -1.1.1.316 * oryza sativa 35000.0 2 PMID:23832214 -1.1.1.316 * spinacia oleracea 75000.0 4 PMID:15509850 -1.1.1.317 * rauvolfia serpentina 38000.0 2 PMID:18409028 -1.1.1.318 * clarkia breweri 38000.0 2 PMID:18208524 -1.1.1.318 * gymnadenia odoratissima 36200.0 2 PMID:25239559 -1.1.1.318 * gymnadenia x densiflora 36200.0 2 PMID:25239559 -1.1.1.322 * anethum foeniculum 89000.0 1 * -1.1.1.323 * tanacetum vulgare 66500.0 1 * -1.1.1.324 * nepeta racemosa 63000.0 2 PMID:7726550 -1.1.1.324 * rauvolfia serpentina 50000.0 2 PMID:1864846 -1.1.1.325 * chlorobaculum tepidum 55000.0 2 * -1.1.1.325 * musca domestica 51000.0 2 PMID:27704475 -1.1.1.326 * zingiber zerumbet 28700.0 1 PMID:21668645 -1.1.1.327 * pseudomonas putida 38400.0 1 PMID:8334169 -1.1.1.330 * gossypium hirsutum 34500.0 1 PMID:20370610 -1.1.1.331 * dysosma tsayuensis 29200.0 1 * -1.1.1.331 * forsythia x intermedia 32000.0 1 PMID:11278426 -1.1.1.331 * podophyllum peltatum 32000.0 1 PMID:11278426 -1.1.1.332 * aspergillus fumigatus 118000.0 2 PMID:20526482 -1.1.1.332 * trichophyton benhamiae 128000.0 3 PMID:22403186 -1.1.1.334 * erythroxylum coca 36910.0 1 PMID:22665766 -1.1.1.335 * pseudomonas aeruginosa 38271.0 1 PMID:19348502 -1.1.1.336 * escherichia coli 100000.0 2 PMID:7048003 -1.1.1.336 * methanococcus maripaludis 200000.0 3 PMID:18263721 -1.1.1.336 * pyrococcus horikoshii 92000.0 2 PMID:17565184 -1.1.1.337 * methanocaldococcus jannaschii 150000.0 2 PMID:15014443 -1.1.1.337 * weissella confusa 125000.0 3 PMID:7643402 -1.1.1.338 * chromohalobacter israelensis 37000.0 1 PMID:20007648 -1.1.1.339 * aggregatibacter actinomycetemcomitans 30700.0 1 PMID:10702238 -1.1.1.34 * alisma plantago-aquatica subsp. orientale 66500.0 2 PMID:26546781 -1.1.1.34 * arabidopsis thaliana 63000.0 1 PMID:19041104 -1.1.1.34 * centella asiatica 58000.0 1 PMID:26311154 -1.1.1.34 * fusarium oxysporum 11000.0 1 * -1.1.1.34 * haloferax volcanii 46000.0 1 PMID:16969709 -1.1.1.34 * homarus americanus 540000.0 3 PMID:15086315 -1.1.1.34 * homo sapiens 96000.0 2 PMID:15337832 -1.1.1.34 * jatropha curcas 62400.0 1 * -1.1.1.34 * leishmania donovani 45000.0 1 PMID:24239940 -1.1.1.34 * leishmania major 184000.0 2 PMID:10861207 -1.1.1.34 * phaedon cochleariae 97100.0 2 PMID:18070667 -1.1.1.34 * rattus norvegicus 226000.0 3 PMID:3850089;PMID:4985697 -1.1.1.34 * schistosoma mansoni 66000.0 1 PMID:1905241 -1.1.1.34 * streptomyces sp. 100000.0 2 PMID:9973353 -1.1.1.34 * sus scrofa 97150.0 1 PMID:22240315 -1.1.1.340 * streptomyces avermitilis 30183.0 1 PMID:17178094 -1.1.1.341 * salmonella enterica subsp. enterica serovar typhimurium 34106.0 2 PMID:2793832 -1.1.1.342 * salmonella enterica subsp. enterica serovar typhi 55000.0 4 PMID:2793833;PMID:9538012 -1.1.1.343 * bradyrhizobium sp. 130000.0 2 * -1.1.1.343 * gluconacetobacter diazotrophicus 70000.0 1 PMID:32621793 -1.1.1.343 * gluconobacter oxydans 135000.0 2 PMID:20676631 -1.1.1.343 * haloferax volcanii 143000.0 2 PMID:25836736 -1.1.1.345 * enterococcus faecalis 130000.0 6 PMID:11823242;PMID:18391442 -1.1.1.345 * haloferax mediterranei 101400.0 4 PMID:11120357;PMID:19342795 -1.1.1.345 * lacticaseibacillus paracasei 74000.0 3 PMID:1840590;PMID:9126843 -1.1.1.345 * lactiplantibacillus plantarum 37183.0 2 PMID:1840590;PMID:9126843 -1.1.1.345 * lactobacillus delbrueckii 36948.0 1 PMID:7925358 -1.1.1.345 * lactococcus cremoris 70000.0 2 PMID:19047348 -1.1.1.345 * lactococcus lactis 70000.0 3 PMID:19047348 -1.1.1.346 * brevibacterium ketosoreductum 72000.0 2 PMID:9501529 -1.1.1.346 * corynebacterium sp. 140000.0 6 PMID:11917149;PMID:3597405 -1.1.1.346 * escherichia coli 31800.0 4 PMID:10427017;PMID:11934293 -1.1.1.347 * carpoglyphus lactis 56200.0 3 PMID:18422649 -1.1.1.347 * castellaniella defragrans 91000.0 6 PMID:22286981 -1.1.1.348 * medicago sativa 38000.0 5 PMID:7625843;PMID:7805842;PMID:8071365 -1.1.1.349 * aspergillus parasiticus 36000.0 2 PMID:10584035 -1.1.1.35 * brassica napus 35000.0 2 PMID:15708363 -1.1.1.35 * clostridium butyricum 60000.0 2 PMID:24699745 -1.1.1.35 * cupriavidus necator 87000.0 3 PMID:25401070 -1.1.1.35 * escherichia coli 270000.0 4 PMID:7012144;PMID:7024730 -1.1.1.35 * euglena gracilis 460000.0 5 PMID:12586899 -1.1.1.35 * homo sapiens 108000.0 3 PMID:10231530;PMID:9553139 -1.1.1.35 * leptospira interrogans serovar copenhageni 47865.0 1 PMID:24884439 -1.1.1.35 * metallosphaera sedula 70000.0 1 PMID:21169482 -1.1.1.35 * mycolicibacterium smegmatis 50300.0 1 PMID:521433 -1.1.1.35 * neurospora crassa 365000.0 2 PMID:1830048 -1.1.1.35 * rattus norvegicus 77000.0 7 PMID:17491019;PMID:640209;PMID:6773478;PMID:7150615 -1.1.1.35 * sus scrofa 76000.0 5 PMID:1121273;PMID:4133851;PMID:9593854 -1.1.1.351 * pseudomonas fluorescens 126000.0 4 PMID:6402366 -1.1.1.351 * thermotoga maritima 53000.0 1 PMID:19497097 -1.1.1.352 * aspergillus parasiticus 60000.0 3 PMID:14602595 -1.1.1.352 * levilactobacillus brevis 100000.0 4 PMID:18323645 -1.1.1.353 * aspergillus parasiticus 390000.0 4 PMID:16349333;PMID:19211038 -1.1.1.354 * carpoglyphus lactis 42800.0 2 PMID:18422649 -1.1.1.356 * yersinia pseudotuberculosis 36000.0 2 PMID:15610039 -1.1.1.357 * comamonas testosteroni 56000.0 4 PMID:25913427;PMID:8944761;PMID:9812981 -1.1.1.357 * homo sapiens 39000.0 5 PMID:11104674;PMID:8172617;PMID:9716498 -1.1.1.357 * pseudomonas sp. 28000.0 1 PMID:8944761 -1.1.1.358 * candida parapsilosis 41600.0 8 PMID:14593510;PMID:19923737;PMID:2644973 -1.1.1.359 * saccharolobus solfataricus 160000.0 7 PMID:12824170;PMID:3827812 -1.1.1.359 * thermoplasma acidophilum 155000.0 3 PMID:2803257;PMID:8436115 -1.1.1.36 * aeromonas hydrophila 26300.0 1 PMID:15983806 -1.1.1.36 * azotobacter vinelandii 77000.0 1 * -1.1.1.36 * cupriavidus necator 84000.0 1 * -1.1.1.36 * methylorubrum extorquens 141000.0 3 * -1.1.1.36 * methylorubrum rhodesianum 340000.0 3 * -1.1.1.36 * mycolicibacterium smegmatis 100000.0 1 PMID:28126742;PMID:3286259 -1.1.1.36 * rattus norvegicus 76000.0 1 PMID:3516072 -1.1.1.36 * rickettsia felis 101000.0 1 PMID:33620038 -1.1.1.36 * streptomyces coelicolor 250000.0 3 * -1.1.1.36 * zoogloea ramigera 100000.0 5 PMID:28126742;PMID:3286259;PMID:3542050 -1.1.1.360 * picrophilus oshimae 160000.0 3 PMID:15691337 -1.1.1.360 * thermoplasma volcanium 158000.0 3 PMID:24816096 -1.1.1.362 * streptomyces sp. 25632.0 1 PMID:8655529 -1.1.1.363 * leuconostoc mesenteroides 69000.0 4 PMID:11106478;PMID:20608171;PMID:2071589;PMID:23770076 -1.1.1.363 * pseudomonas aeruginosa 500000.0 2 PMID:28986240 -1.1.1.364 * streptomyces sp. 52000.0 1 PMID:17053005 -1.1.1.365 * aspergillus niger 44000.0 1 PMID:18768163 -1.1.1.365 * botrytis cinerea 49200.0 2 PMID:21683149 -1.1.1.365 * euglena gracilis 39000.0 2 PMID:17090924 -1.1.1.365 * trichoderma reesei 40000.0 1 PMID:16101307 -1.1.1.366 * vitis vinifera 40000.0 1 PMID:16567629 -1.1.1.367 * pseudomonas aeruginosa 43600.0 1 PMID:12464616 -1.1.1.367 * staphylococcus aureus 43600.0 1 PMID:12464616 -1.1.1.368 * thauera aromatica 78000.0 2 PMID:10406950 -1.1.1.369 * bacillus subtilis 160000.0 2 PMID:112095 -1.1.1.37 * [bacillus] caldotenax 134900.0 3 PMID:31301348;PMID:6990969 -1.1.1.37 * acinetobacter lwoffii 61000.0 2 PMID:191315 -1.1.1.37 * ananas comosus 160000.0 3 * -1.1.1.37 * arabidopsis thaliana 70000.0 5 PMID:15265031;PMID:26095832;PMID:29194485;PMID:32897311;PMID:6990969;PMID:9211715 -1.1.1.37 * archaeoglobus fulgidus 70000.0 2 PMID:15265031;PMID:29194485;PMID:32897311;PMID:6469942;PMID:6769486;PMID:6990969;PMID:8900056;PMID:9211715;PMID:9834842 -1.1.1.37 * aspergillus niger 68000.0 2 PMID:15265031;PMID:6469942;PMID:6769486;PMID:8900056;PMID:9211715;PMID:9834842 -1.1.1.37 * bacillus sp. (in: firmicutes) 140900.0 3 PMID:22965554;PMID:6990969 -1.1.1.37 * bacillus subtilis 148000.0 6 PMID:238957;PMID:6990969;PMID:7305925 -1.1.1.37 * badhamia polycephala 69500.0 3 PMID:945747 -1.1.1.37 * beggiatoa leptomitoformis 172000.0 2 * -1.1.1.37 * bos taurus 62000.0 2 PMID:7305925 -1.1.1.37 * bradyrhizobium japonicum 139000.0 3 PMID:3114237 -1.1.1.37 * canis lupus familiaris 75000.0 2 PMID:190515 -1.1.1.37 * ceratonia siliqua 65000.0 2 PMID:22965554;PMID:6990969 -1.1.1.37 * cereibacter sphaeroides 148000.0 3 PMID:19747101 -1.1.1.37 * chloroflexus aurantiacus 32000.0 1 PMID:15321717;PMID:16306697;PMID:6990969 -1.1.1.37 * citrullus lanatus 76000.0 1 * -1.1.1.37 * clonorchis sinensis 62000.0 1 PMID:18311572 -1.1.1.37 * coccochloris peniocystis 90000.0 1 * -1.1.1.37 * comamonas testosteroni 75000.0 4 PMID:238957;PMID:6990969 -1.1.1.37 * corynebacterium glutamicum 130000.0 2 PMID:16233457;PMID:17487443;PMID:3114237 -1.1.1.37 * delftia acidovorans 43000.0 1 PMID:238957 -1.1.1.37 * dictyostelium discoideum 70000.0 1 PMID:7142959;PMID:7305925;PMID:9834842 -1.1.1.37 * drosophila melanogaster 68000.0 1 PMID:4313528 -1.1.1.37 * drosophila virilis 68000.0 1 PMID:4313528 -1.1.1.37 * escherichia coli 117000.0 7 PMID:19724119;PMID:238957;PMID:3114237 -1.1.1.37 * eucalyptus globulus 38000.0 1 PMID:9834842 -1.1.1.37 * euglena gracilis 72400.0 5 * -1.1.1.37 * flavobacterium frigidimaris 123000.0 2 PMID:15321717;PMID:16306697;PMID:6990969 -1.1.1.37 * gallus sp. 67000.0 1 PMID:6990969 -1.1.1.37 * geobacillus stearothermophilus 138000.0 3 PMID:6990969 -1.1.1.37 * glaesserella parasuis 68400.0 2 PMID:9244395 -1.1.1.37 * glycine max 69400.0 4 * -1.1.1.37 * haloarcula marismortui 132000.0 3 PMID:10653644;PMID:15194233;PMID:8476859 -1.1.1.37 * halobacterium salinarum 84000.0 2 PMID:901751 -1.1.1.37 * heliocidaris crassispina 65000.0 2 PMID:15265031;PMID:6469942;PMID:6769486;PMID:8900056;PMID:9211715;PMID:9834842 -1.1.1.37 * homo sapiens 72000.0 2 PMID:25606688;PMID:6625603;PMID:9269720 -1.1.1.37 * ignicoccus islandicus 133000.0 2 PMID:31301348;PMID:6990969 -1.1.1.37 * laceyella sacchari 140000.0 4 PMID:15321717;PMID:16306697;PMID:3109450;PMID:6990969 -1.1.1.37 * lemna minor 140000.0 2 * -1.1.1.37 * macromonas bipunctata 92000.0 2 * -1.1.1.37 * mesembryanthemum cordifolium 83000.0 2 * -1.1.1.37 * mesembryanthemum crystallinum 39500.0 1 * -1.1.1.37 * metallosphaera sedula 133000.0 1 PMID:30638660 -1.1.1.37 * methanospirillum hungatei 64200.0 3 PMID:35274;PMID:7305925 -1.1.1.37 * methanothermus fervidus 70000.0 1 PMID:7142959;PMID:7305925;PMID:9834842 -1.1.1.37 * methylorubrum extorquens 137400.0 1 PMID:30279311 -1.1.1.37 * methylosinus trichosporium 140000.0 3 PMID:27682078 -1.1.1.37 * methylotuvimicrobium alcaliphilum 70000.0 3 PMID:27682078 -1.1.1.37 * mycobacterium sp. 53000.0 1 PMID:7305925 -1.1.1.37 * mycolicibacterium phlei 86860.0 3 PMID:922015 -1.1.1.37 * neurospora crassa 67000.0 2 PMID:6990969;PMID:7305925 -1.1.1.37 * ovis aries 67000.0 1 PMID:6990969 -1.1.1.37 * phytophthora infestans 90000.0 6 PMID:19249364 -1.1.1.37 * plasmodium falciparum 160000.0 2 PMID:19184366 -1.1.1.37 * priestia megaterium 138000.0 2 PMID:16233457;PMID:3114237 -1.1.1.37 * pyrobaculum calidifontis 140000.0 3 PMID:26507956 -1.1.1.37 * pyrobaculum islandicum 150000.0 4 PMID:16233457;PMID:17487443 -1.1.1.37 * rasamsonia emersonii 70000.0 2 PMID:15265031;PMID:29194485;PMID:32897311;PMID:6469942;PMID:6769486;PMID:6990969;PMID:8900056;PMID:9211715;PMID:9834842 -1.1.1.37 * rattus norvegicus 71600.0 2 PMID:7142202;PMID:7142959;PMID:7305925;PMID:9834842 -1.1.1.37 * rhodobacter capsulatus 148000.0 7 PMID:15265031;PMID:3114237;PMID:3137931;PMID:6469942;PMID:6769486;PMID:8900056;PMID:9211715;PMID:9834842 -1.1.1.37 * rhodocyclus purpureus 60000.0 4 PMID:3114237 -1.1.1.37 * rhodomicrobium vannielii 140000.0 5 PMID:3114237;PMID:3137931 -1.1.1.37 * rhodopseudomonas palustris 180000.0 4 PMID:16827662 -1.1.1.37 * rhodospirillum rubrum 146000.0 9 PMID:16233457;PMID:3114237;PMID:3137931 -1.1.1.37 * rhodovulum steppense 280000.0 3 PMID:29297253 -1.1.1.37 * saccharomyces cerevisiae 170000.0 3 PMID:7305925;PMID:7918385 -1.1.1.37 * salinibacter ruber 33000.0 1 PMID:15194233 -1.1.1.37 * salmo sp. 68000.0 1 * -1.1.1.37 * solanum lycopersicum 76000.0 2 PMID:190515 -1.1.1.37 * spinacia oleracea 180000.0 6 * -1.1.1.37 * streptomyces avermitilis 35000.0 2 PMID:20845078 -1.1.1.37 * streptomyces coelicolor 73350.0 3 PMID:21071865 -1.1.1.37 * sulfolobus acidocaldarius 134000.0 6 PMID:3109450;PMID:6990969 -1.1.1.37 * sus scrofa 74000.0 7 PMID:3114237;PMID:641996;PMID:6990969 -1.1.1.37 * syntrophobacter fumaroxidans 68000.0 2 PMID:15265031;PMID:6469942;PMID:6769486;PMID:8900056;PMID:9211715;PMID:9834842 -1.1.1.37 * taenia solium 64000.0 7 PMID:19277715;PMID:21439955 -1.1.1.37 * thermobifida fusca 79120.0 2 PMID:15265031;PMID:29194485;PMID:32897311;PMID:6990969;PMID:9211715 -1.1.1.37 * thermoplasma acidophilum 144000.0 4 PMID:3741624 -1.1.1.37 * thermus aquaticus 85040.0 4 PMID:238957;PMID:6990969;PMID:7305925 -1.1.1.37 * thermus thermophilus 72000.0 5 PMID:15265031;PMID:24386145;PMID:6469942;PMID:6769486;PMID:7305925;PMID:8900056;PMID:9211715;PMID:9269720;PMID:9834842 -1.1.1.37 * thunnus albacares 70000.0 2 PMID:6990969;PMID:7142959;PMID:7305925;PMID:9834842 -1.1.1.37 * trichomonas gallinae 72000.0 1 PMID:6625603;PMID:9269720 -1.1.1.37 * trichomonas vaginalis 60000.0 2 PMID:6769486;PMID:9269720 -1.1.1.37 * tritrichomonas suis 244000.0 2 PMID:9269720 -1.1.1.37 * vigna mungo 38000.0 1 * -1.1.1.37 * vogesella indigofera 67000.0 2 PMID:3109450;PMID:6990969 -1.1.1.37 * vulcanithermus mediatlanticus 128000.0 3 PMID:16266275 -1.1.1.37 * zea mays 126600.0 6 PMID:23313174 -1.1.1.372 * trichoderma reesei 36232.0 1 PMID:16930134 -1.1.1.373 * escherichia coli 123000.0 1 * -1.1.1.374 * methanococcus maripaludis 305000.0 2 PMID:18634748 -1.1.1.375 * archaeoglobus fulgidus 57000.0 1 PMID:11513609 -1.1.1.375 * methanocaldococcus jannaschii 113000.0 1 PMID:11513609 -1.1.1.376 * azospirillum brasilense 175000.0 4 PMID:16326697 -1.1.1.376 * haloferax volcanii 130000.0 3 PMID:23949136;PMID:32055827 -1.1.1.376 * rhizobium leguminosarum bv. trifolii 67600.0 2 PMID:25236800 -1.1.1.377 * thermoplasma acidophilum 34000.0 2 PMID:22481639 -1.1.1.378 * sphingomonas sp. 26500.0 1 PMID:19187228 -1.1.1.379 * rhodotorula graminis 77000.0 2 * -1.1.1.38 * agrobacterium tumefaciens 580000.0 1 PMID:96110 -1.1.1.38 * citrobacter freundii 190000.0 1 PMID:96110 -1.1.1.38 * clostridium tetanomorphum 84000.0 1 PMID:96110 -1.1.1.38 * erwinia aroidea 200000.0 1 PMID:96110 -1.1.1.38 * escherichia coli b 220000.0 2 PMID:96110 -1.1.1.38 * escherichia coli k-12 500000.0 4 PMID:17215140;PMID:96110 -1.1.1.38 * escherichia coli w 220000.0 3 PMID:4144085 -1.1.1.38 * klebsiella aerogenes 240000.0 2 PMID:96110 -1.1.1.38 * proteus vulgaris 180000.0 1 PMID:96110 -1.1.1.384 * saccharopolyspora spinosa 38000.0 2 PMID:18345667 -1.1.1.384 * streptomyces antibioticus 35834.0 1 PMID:10770761 -1.1.1.386 * ips pini 117000.0 2 PMID:22101251;PMID:26953347 -1.1.1.387 * pyrobaculum calidifontis 51000.0 1 PMID:29353380 -1.1.1.388 * haloferax volcanii 59000.0 2 PMID:25836736 -1.1.1.39 * amaranthus cruentus 121000.0 3 PMID:24444721 -1.1.1.39 * arabidopsis thaliana 125000.0 5 PMID:18223148;PMID:20133948 -1.1.1.39 * atriplex spongiosa 300000.0 2 PMID:4155265 -1.1.1.39 * bradyrhizobium japonicum 388000.0 2 PMID:9758846 -1.1.1.39 * brassica oleracea 400000.0 1 * -1.1.1.39 * brevundimonas diminuta 680000.0 2 * -1.1.1.39 * clupea harengus 61000.0 2 PMID:23313742;PMID:27630022 -1.1.1.39 * crassula argentea 491000.0 9 PMID:16663114;PMID:3597379 -1.1.1.39 * oryctolagus cuniculus 270000.0 1 PMID:4147645;PMID:4151949 -1.1.1.39 * pseudomonas aeruginosa 270000.0 2 PMID:4147645;PMID:4151949 -1.1.1.39 * rhodopseudomonas palustris 650000.0 2 PMID:20057150 -1.1.1.39 * sinorhizobium meliloti 82000.0 1 PMID:10407149 -1.1.1.39 * solanum tuberosum 490000.0 5 PMID:7294802 -1.1.1.39 * tritrichomonas suis 308000.0 1 PMID:8278219 -1.1.1.39 * vigna unguiculata 120000.0 3 * -1.1.1.391 * [clostridium] innocuum 56000.0 1 PMID:2764572 -1.1.1.391 * blautia producta 132000.0 1 PMID:2752021 -1.1.1.395 * eubacterium sp. 27000.0 1 PMID:2376563;PMID:7766153 -1.1.1.396 * chlorobaculum tepidum 37000.0 1 PMID:26088139 -1.1.1.398 * rhodococcus sp. ad45 25000.0 1 PMID:10094686 -1.1.1.399 * escherichia coli 46000.0 1 PMID:8550422 -1.1.1.399 * fusobacterium nucleatum 68000.0 1 PMID:1884985 -1.1.1.399 * micrococcus aerogenes 78000.0 1 PMID:4396793 -1.1.1.4 * bacillus subtilis 40000.0 3 PMID:24100567;PMID:25663525;PMID:26393961;PMID:26454865 -1.1.1.4 * corynebacterium glutamicum 35000.0 1 PMID:25663525;PMID:26393961 -1.1.1.4 * heyndrickxia coagulans 40000.0 2 PMID:24100567;PMID:26454865 -1.1.1.4 * klebsiella aerogenes 61000.0 2 PMID:2040298 -1.1.1.4 * klebsiella pneumoniae 45000.0 1 PMID:24429283 -1.1.1.4 * lactococcus lactis 170000.0 1 PMID:16348209 -1.1.1.4 * paenibacillus polymyxa 107000.0 3 PMID:22961752;PMID:25056 -1.1.1.4 * pyrococcus furiosus 32000.0 2 PMID:16391048 -1.1.1.4 * rhodococcus erythropolis 45000.0 2 PMID:25903366 -1.1.1.4 * saccharomyces cerevisiae 140000.0 4 PMID:10938079;PMID:2222122 -1.1.1.4 * serratia marcescens 39000.0 2 PMID:24981852;PMID:25663525;PMID:26393961 -1.1.1.40 * arabidopsis thaliana 249000.0 5 PMID:18288573;PMID:19725876 -1.1.1.40 * azospirillum brasilense 710000.0 1 PMID:32485238 -1.1.1.40 * clupea harengus 64000.0 1 PMID:23313742;PMID:7757881 -1.1.1.40 * corynebacterium glutamicum 105000.0 2 PMID:10877795 -1.1.1.40 * egeria densa 72000.0 1 PMID:11172800 -1.1.1.40 * escherichia coli 83000.0 1 PMID:22068497 -1.1.1.40 * flaveria floridana 62000.0 1 PMID:11172800 -1.1.1.40 * haloxylon persicum 67000.0 1 PMID:11172800 -1.1.1.40 * homo sapiens 257000.0 4 PMID:1761063;PMID:1935931;PMID:23313742;PMID:7757881 -1.1.1.40 * hydrilla verticillata 72000.0 3 PMID:17638114 -1.1.1.40 * mangifera indica 258000.0 2 * -1.1.1.40 * mesembryanthemum cordifolium 264000.0 3 * -1.1.1.40 * mesembryanthemum crystallinum 64000.0 1 PMID:11172800;PMID:24861319 -1.1.1.40 * methylosinus trichosporium 480000.0 1 PMID:31228930 -1.1.1.40 * mortierella alpina 64000.0 1 PMID:11172800;PMID:24861319 -1.1.1.40 * nicotiana benthamiana 280000.0 5 PMID:18281746 -1.1.1.40 * nicotiana tabacum 260000.0 4 PMID:18272530 -1.1.1.40 * oryctolagus cuniculus 180000.0 1 PMID:4151949 -1.1.1.40 * phaeodactylum tricornutum 60400.0 1 PMID:27387324 -1.1.1.40 * pseudomonas aeruginosa 90000.0 2 PMID:4147645 -1.1.1.40 * ricinus communis 285000.0 4 PMID:15313216;PMID:17292466 -1.1.1.40 * saccharolobus solfataricus 105000.0 2 PMID:3108257 -1.1.1.40 * sinorhizobium meliloti 82000.0 1 PMID:10407149 -1.1.1.40 * solanum lycopersicum 265000.0 1 * -1.1.1.40 * sus scrofa 227000.0 2 PMID:4404450 -1.1.1.40 * trichomonas vaginalis 80000.0 2 PMID:15033531 -1.1.1.40 * triticum aestivum 72000.0 4 PMID:11172800;PMID:17292466 -1.1.1.40 * zea mays 480000.0 16 PMID:11172800;PMID:12374297;PMID:12562758;PMID:17292466;PMID:17885087;PMID:18622731;PMID:22896889;PMID:4154781 -1.1.1.400 * mycolicibacterium austroafricanum 64000.0 1 PMID:16622053 -1.1.1.401 * haloferax volcanii 139000.0 1 PMID:30707467 -1.1.1.401 * sphingomonas sp. 30000.0 2 PMID:19187228 -1.1.1.404 * sphingobium chlorophenolicum 100000.0 4 PMID:19325743;PMID:23676275 -1.1.1.405 * haemophilus influenzae 106400.0 3 PMID:10094675;PMID:15362865 -1.1.1.405 * staphylococcus aureus 129000.0 3 PMID:15362865 -1.1.1.406 * cereibacter sphaeroides 110000.0 5 PMID:15296184;PMID:19778027;PMID:7551050 -1.1.1.41 * acidithiobacillus thiooxidans 90000.0 2 PMID:12204383 -1.1.1.41 * arabidopsis thaliana 40620.0 11 PMID:16527867 -1.1.1.41 * azotobacter vinelandii 80000.0 1 PMID:15817777 -1.1.1.41 * campylobacter sp. 81000.0 2 PMID:25775177 -1.1.1.41 * chlamydomonas reinhardtii 320000.0 2 PMID:9733544 -1.1.1.41 * colwellia maris 80000.0 1 PMID:15817777 -1.1.1.41 * congregibacter litoralis 390000.0 2 PMID:25942017 -1.1.1.41 * homo sapiens 238000.0 3 PMID:16737955;PMID:17432878 -1.1.1.41 * lathyrus oleraceus 320000.0 1 PMID:9733544 -1.1.1.41 * methylobacillus flagellatus 83600.0 1 PMID:28423051 -1.1.1.41 * methylococcus capsulatus 145000.0 2 PMID:17160675 -1.1.1.41 * mycobacterium tuberculosis 290000.0 4 PMID:19052369 -1.1.1.41 * ostreococcus sp. 'lucimarinus' 92000.0 2 PMID:25775177 -1.1.1.41 * ostreococcus tauri 108000.0 3 PMID:25724193 -1.1.1.41 * phaeodactylum tricornutum 110000.0 1 PMID:32824636 -1.1.1.41 * phycomyces blakesleeanus 338000.0 2 PMID:8664264 -1.1.1.41 * pyrococcus furiosus 70000.0 2 PMID:11533060 -1.1.1.41 * rhodotorula toruloides 191800.0 1 * -1.1.1.41 * saccharomyces cerevisiae 335000.0 16 PMID:11042198;PMID:12562755;PMID:16621803;PMID:16884682;PMID:19645416;PMID:21861471 -1.1.1.41 * streptococcus mutans 70000.0 1 PMID:23484056 -1.1.1.41 * sus scrofa 340000.0 5 PMID:203934;PMID:7287723 -1.1.1.41 * trypanosoma brucei brucei 97500.0 1 PMID:28642005 -1.1.1.41 * xylella fastidiosa 75500.0 1 PMID:28220528 -1.1.1.41 * yarrowia lipolytica 412000.0 2 PMID:15627396 -1.1.1.41 * zymomonas mobilis 74000.0 2 PMID:22117777 -1.1.1.412 * stenotrophomonas maltophilia 77124.0 1 PMID:21958090 -1.1.1.413 * streptomyces virginiae 54000.0 1 PMID:12193632 -1.1.1.415 * papaver somniferum 42000.0 1 PMID:24708518 -1.1.1.416 * arthrobacter sp. cr-7 242000.0 1 PMID:3533936 -1.1.1.42 * acinetobacter baumannii 83500.0 1 PMID:33290880 -1.1.1.42 * acinetobacter calcoaceticus 360000.0 2 PMID:849 -1.1.1.42 * aeropyrum pernix 70000.0 2 PMID:11533060 -1.1.1.42 * arabidopsis thaliana 90000.0 1 PMID:16665339;PMID:30625997;PMID:3337829;PMID:9252109 -1.1.1.42 * archaeoglobus fulgidus 80000.0 3 PMID:1295895;PMID:17401542;PMID:4147570;PMID:9325430 -1.1.1.42 * aspergillus niger 60000.0 1 PMID:3753466 -1.1.1.42 * azotobacter vinelandii 80000.0 1 PMID:1295895;PMID:4147570;PMID:9325430 -1.1.1.42 * bacillus sp. (in: firmicutes) 90000.0 1 PMID:16665339;PMID:30625997;PMID:3337829;PMID:9252109 -1.1.1.42 * bacillus subtilis 80000.0 1 PMID:4147570 -1.1.1.42 * bifidobacterium longum subsp. infantis 83000.0 2 PMID:26927087 -1.1.1.42 * bombyx mori 86000.0 1 PMID:21170 -1.1.1.42 * bos taurus 90000.0 3 PMID:15840;PMID:20382;PMID:7447463 -1.1.1.42 * caldococcus noboribetus 90000.0 3 PMID:16665339;PMID:30625997;PMID:3337829;PMID:8951037;PMID:9252109 -1.1.1.42 * capsicum annuum 46705.0 1 PMID:22653649 -1.1.1.42 * cereibacter sphaeroides 105000.0 1 PMID:10847;PMID:23264072 -1.1.1.42 * chlamydomonas reinhardtii 100000.0 3 PMID:23073782;PMID:4147570 -1.1.1.42 * chlorobium limicola 81000.0 3 PMID:11952794 -1.1.1.42 * corynebacterium glutamicum 80000.0 1 PMID:21931217 -1.1.1.42 * desulfobacter vibrioformis 80000.0 1 PMID:1935983;PMID:23073782;PMID:9495015 -1.1.1.42 * escherichia coli 85000.0 4 PMID:1295895;PMID:17401542;PMID:18640291;PMID:4147570;PMID:9325430 -1.1.1.42 * fomitopsis palustris 115000.0 2 PMID:12619682 -1.1.1.42 * fundulus heteroclitus 90000.0 1 PMID:4019464 -1.1.1.42 * geobacillus stearothermophilus 92600.0 1 PMID:4147570 -1.1.1.42 * gryllus firmus 46300.0 1 PMID:21861657 -1.1.1.42 * haloferax volcanii 62000.0 3 PMID:12007799;PMID:8593959 -1.1.1.42 * homo sapiens 53000.0 2 PMID:19291592;PMID:28091 -1.1.1.42 * lathyrus oleraceus 90000.0 2 PMID:10557241;PMID:16665339;PMID:30625997;PMID:3337829;PMID:9252109 -1.1.1.42 * leptolyngbya laminosa 107000.0 2 PMID:10209282 -1.1.1.42 * methylobacillus flagellatus 83600.0 1 PMID:28423051 -1.1.1.42 * microcystis aeruginosa 105000.0 4 PMID:10847;PMID:23264072 -1.1.1.42 * mus musculus 47000.0 1 PMID:19106211 -1.1.1.42 * mycobacterium tuberculosis 320000.0 8 PMID:16194279 -1.1.1.42 * mytilus edulis 45000.0 1 PMID:7460916 -1.1.1.42 * nicotiana tabacum 136000.0 2 PMID:12232226 -1.1.1.42 * pinus spp. 95000.0 2 PMID:9765548 -1.1.1.42 * plasmodium falciparum 90000.0 2 PMID:12694190 -1.1.1.42 * rattus norvegicus 47000.0 2 PMID:12533530;PMID:12859674 -1.1.1.42 * rhodomicrobium vannielii 80000.0 2 PMID:1935983;PMID:23073782;PMID:9495015 -1.1.1.42 * rhodopseudomonas palustris 69100.0 1 * -1.1.1.42 * saccharolobus solfataricus 45000.0 1 PMID:8593959 -1.1.1.42 * saccharomyces cerevisiae 47856.0 3 PMID:15173171 -1.1.1.42 * saccharopolyspora erythraea 130000.0 2 PMID:12967008 -1.1.1.42 * staphylococcus aureus 40000.0 1 PMID:23288593 -1.1.1.42 * streptomyces diastaticus 80000.0 2 PMID:1935983;PMID:23073782;PMID:9495015 -1.1.1.42 * streptomyces lividans 80000.0 2 PMID:19631711 -1.1.1.42 * sus scrofa 99800.0 5 PMID:10847;PMID:12054490;PMID:12207025 -1.1.1.42 * synechocystis sp. 108000.0 2 PMID:1730247 -1.1.1.42 * thermoleophilum minutum 60000.0 2 * -1.1.1.42 * thermotoga maritima 174000.0 4 PMID:11533060 -1.1.1.42 * thermus aquaticus 70000.0 1 PMID:4147570 -1.1.1.42 * thermus thermophilus 54200.0 1 PMID:18776690 -1.1.1.42 * trypanosoma cruzi 45000.0 2 PMID:21291916 -1.1.1.42 * vibrio parahaemolyticus 80000.0 1 PMID:1295895;PMID:4147570;PMID:9325430 -1.1.1.42 * vibrio sp. 85000.0 1 PMID:39069 -1.1.1.42 * xylella fastidiosa 82400.0 1 PMID:28220528 -1.1.1.42 * yarrowia lipolytica 81300.0 2 PMID:23846800 -1.1.1.42 * zea mays 83000.0 1 PMID:10847 -1.1.1.422 * arthrobacter sp. 33000.0 2 * -1.1.1.422 * arthrobacter sp. ts-15 30000.0 2 PMID:31900306 -1.1.1.423 * arthrobacter sp. ts-15 27000.0 2 * -1.1.1.424 * haloarcula marismortui 175000.0 1 PMID:15342590 -1.1.1.424 * haloferax volcanii 165000.0 1 PMID:19584053 -1.1.1.425 * arthrobacter sp. i-552 290000.0 1 PMID:7765713 -1.1.1.425 * pseudarthrobacter phenanthrenivorans 135000.0 1 PMID:30224354 -1.1.1.427 * candida albicans 41000.0 1 PMID:8841374 -1.1.1.427 * saccharolobus solfataricus 149700.0 2 PMID:16849334 -1.1.1.427 * saccharomyces cerevisiae 80000.0 6 PMID:17030441;PMID:17151466;PMID:9920381 -1.1.1.43 * [candida] boidinii 110000.0 1 PMID:7350909 -1.1.1.43 * burkholderia cepacia 123000.0 6 PMID:4154932 -1.1.1.43 * cyberlindnera jadinii 100000.0 1 * -1.1.1.43 * glaesserella parasuis 58000.0 1 PMID:21840023 -1.1.1.43 * lytechinus pictus 52000.0 1 PMID:1639134 -1.1.1.43 * neurospora crassa 120000.0 2 PMID:4154932 -1.1.1.43 * ovis aries 129000.0 6 * -1.1.1.43 * pseudomonas sp. 220000.0 2 PMID:7350909 -1.1.1.43 * rattus norvegicus 110000.0 3 PMID:21930213 -1.1.1.43 * strongylocentrotus purpuratus 52000.0 1 PMID:1639134 -1.1.1.43 * zea mays 55000.0 1 PMID:16653162 -1.1.1.430 * candida parapsilosis 69000.0 3 PMID:14532079 -1.1.1.431 * candida tropicalis 365540.0 5 PMID:19342796 -1.1.1.431 * maudiozyma humilis 36700.0 1 PMID:23711518 -1.1.1.431 * neurospora crassa 60000.0 2 PMID:8620033 -1.1.1.431 * ogataea siamensis 36300.0 1 * -1.1.1.431 * rhizomucor pusillus 59000.0 2 PMID:25041710 -1.1.1.431 * scheffersomyces stipitis 75000.0 1 PMID:30487522 -1.1.1.431 * sungouiella intermedia 58000.0 1 PMID:10681056 -1.1.1.431 * thermomyces lanuginosus 39000.0 1 PMID:30831517 -1.1.1.433 * bifidobacterium catenulatum subsp. kashiwanohense 83000.0 2 PMID:31123167 -1.1.1.436 * acetobacterium woodii 265000.0 6 PMID:24762045;PMID:35748623 -1.1.1.438 * sinomonas cyclohexanicum 102000.0 1 PMID:34583900 -1.1.1.44 * [candida] boidinii 110000.0 2 PMID:31936 -1.1.1.44 * acer pseudoplatanus 49000.0 2 * -1.1.1.44 * arabidopsis thaliana 53600.0 3 PMID:32945878 -1.1.1.44 * arthrobacter globiformis 229000.0 2 * -1.1.1.44 * beta vulgaris 102000.0 2 PMID:1128263;PMID:16284727;PMID:238996;PMID:3163;PMID:4401169;PMID:4830191;PMID:7773202 -1.1.1.44 * candida albicans 63000.0 2 PMID:22094058 -1.1.1.44 * ctenopharyngodon idella 57000.0 1 PMID:124005;PMID:238996;PMID:24772981;PMID:4267298 -1.1.1.44 * cyberlindnera jadinii 111000.0 6 PMID:238996;PMID:33854;PMID:4773872;PMID:4830191;PMID:565189;PMID:786365 -1.1.1.44 * drosophila sp. (in: flies) 104000.0 2 PMID:238996;PMID:4401169;PMID:4772689;PMID:4830191;PMID:6292662 -1.1.1.44 * enterococcus faecalis 115000.0 3 PMID:1128263;PMID:16284727;PMID:236442;PMID:238996;PMID:3163;PMID:4401169;PMID:4830191;PMID:7773202 -1.1.1.44 * escherichia coli 100000.0 2 PMID:26211962;PMID:565189;PMID:786365 -1.1.1.44 * gallus gallus 60000.0 2 PMID:15704497 -1.1.1.44 * geobacillus stearothermophilus 101000.0 6 PMID:124005;PMID:238996;PMID:24772981;PMID:4267298;PMID:4772689;PMID:4830191;PMID:6292662;PMID:6641716;PMID:786365;PMID:9675070 -1.1.1.44 * gryllus firmus 49000.0 1 PMID:24726622 -1.1.1.44 * homo sapiens 104000.0 6 PMID:1128263;PMID:16284727;PMID:238996;PMID:30098336;PMID:3163;PMID:3994686;PMID:4401169;PMID:4830191;PMID:7773202 -1.1.1.44 * neurospora crassa 120000.0 3 PMID:124005;PMID:238996;PMID:24772981;PMID:4267298 -1.1.1.44 * nicotiana tabacum 72000.0 1 * -1.1.1.44 * oryctolagus cuniculus 104000.0 2 PMID:1128263;PMID:16284727;PMID:238996;PMID:3163;PMID:3994686;PMID:4401169;PMID:4830191;PMID:7773202 -1.1.1.44 * ovis aries 129000.0 13 PMID:236441;PMID:237488;PMID:238996;PMID:38116;PMID:4401169;PMID:4773872;PMID:568455;PMID:6641716;PMID:8954568;PMID:9675070 -1.1.1.44 * phormidium sp. 104000.0 2 PMID:1128263;PMID:16284727;PMID:238996;PMID:3163;PMID:3994686;PMID:4401169;PMID:4830191;PMID:7773202 -1.1.1.44 * plasmodium falciparum 79000.0 1 PMID:30098336 -1.1.1.44 * rattus norvegicus 120000.0 6 PMID:1128263;PMID:16284727;PMID:238996;PMID:30506659;PMID:3163;PMID:4401169;PMID:4772689;PMID:4773872;PMID:4830191;PMID:6292662;PMID:7773202 -1.1.1.44 * ricinus communis 55000.0 2 PMID:16660503 -1.1.1.44 * schizosaccharomyces pombe 158000.0 2 PMID:10099784 -1.1.1.44 * spinacia oleracea 110000.0 1 PMID:4144057 -1.1.1.44 * streptococcus pneumoniae 53400.0 1 PMID:16634799 -1.1.1.44 * streptococcus suis 52400.0 1 PMID:18403138 -1.1.1.44 * sus scrofa 83000.0 1 PMID:11218 -1.1.1.44 * trypanosoma brucei 208000.0 2 PMID:24096100 -1.1.1.44 * trypanosoma cruzi 93000.0 3 PMID:14698432 -1.1.1.45 * bos taurus 70000.0 1 PMID:8898089 -1.1.1.45 * drosophila melanogaster 70000.0 5 PMID:37912;PMID:3926004;PMID:4328697 -1.1.1.45 * oryctolagus cuniculus 70000.0 5 PMID:15809331;PMID:18323616;PMID:20620150 -1.1.1.45 * rattus norvegicus 70000.0 1 PMID:8898089 -1.1.1.46 * haloferax volcanii 130000.0 3 PMID:23949136 -1.1.1.47 * bacillus amyloliquefaciens 28000.0 1 PMID:26538191 -1.1.1.47 * bacillus sp. (in: firmicutes) 120000.0 3 PMID:20805024;PMID:24315638;PMID:28587256 -1.1.1.47 * bacillus subtilis 126000.0 4 PMID:21162;PMID:2226786;PMID:6415053 -1.1.1.47 * bacillus thuringiensis serovar kurstaki 56400.0 1 PMID:27363470 -1.1.1.47 * bos taurus 235000.0 3 PMID:7092232;PMID:7553351 -1.1.1.47 * burkholderia cepacia 60000.0 1 PMID:12573242 -1.1.1.47 * corynebacterium sp. 55000.0 4 * -1.1.1.47 * gluconobacter oxydans 153000.0 2 * -1.1.1.47 * homo sapiens 89000.0 1 PMID:19804362 -1.1.1.47 * lysinibacillus sphaericus 120000.0 4 PMID:20805024;PMID:24315638;PMID:2530;PMID:28587256 -1.1.1.47 * oncorhynchus mykiss 230000.0 3 PMID:4397856;PMID:7553351 -1.1.1.47 * priestia megaterium 150000.0 18 PMID:11173533;PMID:12743762;PMID:1629157;PMID:24315638;PMID:2495285;PMID:2513190;PMID:2530;PMID:3113945;PMID:6432532 -1.1.1.47 * rattus norvegicus 98000.0 2 PMID:19255253;PMID:19804362 -1.1.1.47 * saccharolobus solfataricus 164000.0 9 PMID:12824170;PMID:16508107;PMID:16556607;PMID:3827812 -1.1.1.47 * sulfurisphaera tokodaii 160000.0 2 * -1.1.1.47 * sus scrofa 58000.0 1 PMID:6641908 -1.1.1.47 * thermoplasma acidophilum 155000.0 4 PMID:2803257 -1.1.1.47 * thermoproteus tenax 84000.0 2 PMID:9238103 -1.1.1.48 * azotobacter vinelandii 74000.0 1 PMID:16349292 -1.1.1.48 * pseudomonas fluorescens 64000.0 3 PMID:25591389;PMID:4153311 -1.1.1.48 * roseateles saccharophilus 102000.0 3 PMID:1138886;PMID:4149284;PMID:4153311 -1.1.1.49 * [candida] boidinii 120000.0 2 PMID:31936 -1.1.1.49 * agaricus bisporus 138000.0 2 * -1.1.1.49 * anabaena sp. 345000.0 3 PMID:23737 -1.1.1.49 * aquifex aeolicus 55000.0 1 PMID:12215813 -1.1.1.49 * aspergillus aculeatus 105000.0 2 PMID:16202239 -1.1.1.49 * aspergillus nidulans 180000.0 3 PMID:6696427;PMID:8277259 -1.1.1.49 * aspergillus niger 160000.0 3 PMID:8277259 -1.1.1.49 * aspergillus parasiticus 180000.0 2 PMID:6696427;PMID:8277259 -1.1.1.49 * azotobacter vinelandii 52000.0 1 PMID:4055554;PMID:9252113 -1.1.1.49 * bacillus subtilis 120000.0 2 PMID:6292660 -1.1.1.49 * bos indicus 59500.0 1 PMID:18300160 -1.1.1.49 * bos taurus 238700.0 3 PMID:1168837;PMID:25980795 -1.1.1.49 * brugia malayi 300000.0 2 PMID:23506961 -1.1.1.49 * camelus dromedarius 194000.0 3 PMID:22538316;PMID:25610637 -1.1.1.49 * canis lupus familiaris 52500.0 1 PMID:11849992 -1.1.1.49 * coriandrum sativum 73200.0 1 * -1.1.1.49 * cryptococcus neoformans 50000.0 1 PMID:8080277 -1.1.1.49 * cyberlindnera jadinii 110000.0 1 PMID:236439;PMID:4798897;PMID:5363983 -1.1.1.49 * deinococcus radiophilus 130000.0 4 PMID:17846585 -1.1.1.49 * escherichia coli 52000.0 1 PMID:4401601 -1.1.1.49 * geobacillus stearothermophilus 200000.0 2 PMID:4055554;PMID:9252113 -1.1.1.49 * homo sapiens 220000.0 8 PMID:1540638;PMID:18493020;PMID:19284595;PMID:2270145;PMID:236436;PMID:236440 -1.1.1.49 * hordeum vulgare 57000.0 3 PMID:12569406;PMID:24161756 -1.1.1.49 * koliella antarctica 274000.0 2 PMID:23117891 -1.1.1.49 * lathyrus oleraceus 240000.0 3 PMID:3717951;PMID:7144573 -1.1.1.49 * lentilactobacillus buchneri 240000.0 2 PMID:3717951;PMID:7144573 -1.1.1.49 * meleagris gallopavo 75000.0 1 PMID:22900294 -1.1.1.49 * mus musculus 240000.0 4 PMID:3717951;PMID:7144573;PMID:8174754 -1.1.1.49 * neurospora crassa 206000.0 4 PMID:2270145;PMID:236436;PMID:9666312 -1.1.1.49 * oncorhynchus mykiss 48500.0 1 * -1.1.1.49 * ovis aries 120000.0 2 PMID:12530481 -1.1.1.49 * penicillium duponti 126000.0 1 PMID:236438 -1.1.1.49 * petroselinum crispum 77600.0 1 PMID:12071647 -1.1.1.49 * plasmodium falciparum 107000.0 1 PMID:22496096 -1.1.1.49 * pseudomonas fluorescens 265000.0 4 PMID:1257;PMID:6815421 -1.1.1.49 * pseudomonas sp. 150000.0 1 PMID:7350909 -1.1.1.49 * rattus norvegicus 144000.0 6 PMID:10215021;PMID:15328887;PMID:21930213;PMID:30506659;PMID:9219438 -1.1.1.49 * schizosaccharomyces pombe 112000.0 2 PMID:236436;PMID:9666312 -1.1.1.49 * sus scrofa 220000.0 2 PMID:2270145;PMID:236436 -1.1.1.49 * taenia crassiceps 134000.0 2 PMID:18297308 -1.1.1.49 * thermotoga maritima 95000.0 2 PMID:12435510;PMID:12814622 -1.1.1.49 * trypanosoma brucei 158000.0 2 PMID:10215021;PMID:9219438 -1.1.1.49 * trypanosoma cruzi 57500.0 1 PMID:27391210 -1.1.1.49 * zea mays 114000.0 2 PMID:16663658 -1.1.1.50 * bos taurus 35000.0 1 PMID:1592159 -1.1.1.50 * comamonas testosteroni 100000.0 7 PMID:10833462;PMID:19683506;PMID:25913427;PMID:4137094 -1.1.1.50 * eggerthella lenta 205000.0 1 PMID:39496 -1.1.1.50 * eubacterium sp. 27000.0 1 PMID:7766153 -1.1.1.50 * gallus gallus 66000.0 2 PMID:2278841;PMID:2308341 -1.1.1.50 * homo sapiens 65000.0 3 PMID:1390284;PMID:19018576 -1.1.1.50 * mus musculus 34000.0 2 PMID:16168;PMID:2933398;PMID:3170514;PMID:6586631 -1.1.1.50 * pseudomonas aeruginosa 32000.0 1 PMID:26193374 -1.1.1.50 * pseudomonas putida 45000.0 2 * -1.1.1.50 * pseudomonas sp. 47000.0 3 PMID:16754984;PMID:16905772;PMID:9928117 -1.1.1.50 * rattus norvegicus 75000.0 10 PMID:16168;PMID:17475203;PMID:1793046;PMID:18291663;PMID:18574251;PMID:2268552;PMID:2933398;PMID:3170514;PMID:3468121;PMID:6586631 -1.1.1.51 * [clostridium] innocuum 80000.0 1 PMID:3861198 -1.1.1.51 * cavia porcellus 41475.0 2 PMID:16143518;PMID:513731 -1.1.1.51 * comamonas testosteroni 98500.0 1 PMID:193845 -1.1.1.51 * digitalis lanata 28561.0 1 PMID:17564944 -1.1.1.51 * homo sapiens 90400.0 3 PMID:11940569;PMID:4405572 -1.1.1.51 * mesocricetus auratus 37000.0 1 PMID:26002966 -1.1.1.51 * rattus norvegicus 70000.0 1 PMID:4152755 -1.1.1.53 * agathobaculum desmolans 134500.0 1 PMID:28314858 -1.1.1.53 * clarias gariepinus 30000.0 1 PMID:19401204 -1.1.1.53 * comamonas testosteroni 23380.0 1 PMID:17258342 -1.1.1.53 * oncorhynchus mykiss 30140.0 1 PMID:17543385 -1.1.1.53 * streptomyces exfoliatus 111000.0 3 PMID:7922040 -1.1.1.53 * sus scrofa 30500.0 1 PMID:3240999 -1.1.1.54 * nicotiana tabacum 74000.0 6 PMID:11117876;PMID:17945329 -1.1.1.54 * pseudomonas putida 151000.0 2 PMID:10347052 -1.1.1.56 * cereibacter sphaeroides 50000.0 2 PMID:1527498 -1.1.1.56 * escherichia coli 26000.0 1 PMID:32451803 -1.1.1.56 * gluconobacter oxydans 100000.0 2 PMID:11272814;PMID:26693956 -1.1.1.56 * klebsiella aerogenes 110000.0 5 PMID:25837508;PMID:4376942;PMID:4618776 -1.1.1.56 * pantoea agglomerans 92000.0 2 PMID:11272814;PMID:26693956 -1.1.1.56 * providencia alcalifaciens 104000.0 3 PMID:11272814;PMID:26693956 -1.1.1.56 * sphingomonas sp. 117000.0 1 PMID:32639976 -1.1.1.59 * bacillus cereus 32000.0 1 PMID:19517068 -1.1.1.59 * candida albicans 40000.0 2 PMID:24497638 -1.1.1.6 * anaerobium acetethylicum 40072.0 1 PMID:28004884 -1.1.1.6 * arthrobacter sp. 132000.0 1 * -1.1.1.6 * cellulomonas sp. 390000.0 4 PMID:7981227 -1.1.1.6 * clostridium butyricum 181000.0 1 PMID:11412332 -1.1.1.6 * escherichia coli 320000.0 7 PMID:19725101;PMID:20585771;PMID:27233513;PMID:30839292 -1.1.1.6 * geobacillus stearothermophilus 39500.0 1 PMID:11134946 -1.1.1.6 * heyndrickxia coagulans 86000.0 1 PMID:33020946 -1.1.1.6 * klebsiella aerogenes 180000.0 2 PMID:6988402 -1.1.1.6 * klebsiella pneumoniae 710000.0 4 PMID:20585771;PMID:31635443 -1.1.1.6 * klebsiella pneumoniae subsp. pneumoniae 370000.0 1 PMID:31635443 -1.1.1.6 * ogataea angusta 72000.0 2 * -1.1.1.6 * pichia membranifaciens 80000.0 2 * -1.1.1.6 * priestia megaterium 160000.0 2 * -1.1.1.6 * salmonella enterica 39000.0 1 PMID:20585771 -1.1.1.6 * salmonella enterica subsp. enterica serovar typhimurium 38742.0 2 PMID:19574643 -1.1.1.6 * schizosaccharomyces pombe 400000.0 2 * -1.1.1.6 * serratia marcescens 39000.0 1 PMID:24981852 -1.1.1.6 * serratia sp. (in: enterobacteria) 160000.0 2 PMID:24637749 -1.1.1.6 * thermoanaerobacterium thermosaccharolyticum 40400.0 1 PMID:26975764 -1.1.1.6 * thermus thermophilus 170000.0 2 PMID:19932956 -1.1.1.60 * mycosarcoma maydis 85000.0 3 PMID:21305026 -1.1.1.60 * pseudomonas putida 104000.0 3 PMID:13900766;PMID:4300866 -1.1.1.61 * arabidopsis thaliana 30300.0 1 PMID:12882961 -1.1.1.61 * clostridium kluyveri 86000.0 2 PMID:7606170 -1.1.1.61 * cupriavidus necator 66000.0 2 PMID:15027565 -1.1.1.61 * escherichia coli 143000.0 3 PMID:19372223 -1.1.1.61 * porphyromonas gingivalis 42000.0 2 PMID:26432601 -1.1.1.62 * equus caballus 68500.0 2 PMID:6584179 -1.1.1.62 * gallus gallus 97000.0 2 PMID:6936398 -1.1.1.62 * homo sapiens 80000.0 9 PMID:1525049;PMID:17978863;PMID:18220769;PMID:28430630;PMID:3855619;PMID:5045524;PMID:8994190 -1.1.1.62 * oryctolagus cuniculus 64000.0 2 PMID:160696 -1.1.1.62 * ovis aries 104000.0 2 PMID:23096084;PMID:4314937 -1.1.1.62 * sus scrofa 75000.0 2 PMID:8943781 -1.1.1.64 * cavia porcellus 39000.0 2 PMID:18133 -1.1.1.64 * rattus norvegicus 180000.0 1 PMID:2821659 -1.1.1.64 * sus scrofa 36500.0 4 PMID:2821659 -1.1.1.65 * schizosaccharomyces pombe 41000.0 1 PMID:10438489 -1.1.1.67 * absidia glauca 133000.0 2 PMID:5111 -1.1.1.67 * aspergillus fumigatus 58000.0 1 PMID:18983992 -1.1.1.67 * burkholderia cepacia 64500.0 1 PMID:6281243 -1.1.1.67 * cereibacter sphaeroides 54000.0 3 PMID:2789134;PMID:9274047 -1.1.1.67 * fructilactobacillus sanfranciscensis 53000.0 2 PMID:12670693 -1.1.1.67 * leuconostoc mesenteroides 138000.0 3 PMID:12226722;PMID:236430 -1.1.1.67 * leuconostoc pseudomesenteroides 155000.0 3 PMID:12560988 -1.1.1.67 * levilactobacillus brevis 36000.0 1 PMID:15917616 -1.1.1.67 * pseudomonas fluorescens 55000.0 6 PMID:10441145;PMID:12146981;PMID:19266906;PMID:20639204;PMID:9116029 -1.1.1.67 * saccharina japonica 115000.0 2 PMID:24830763 -1.1.1.67 * saccharomyces cerevisiae 53000.0 1 * -1.1.1.67 * sinorhizobium meliloti 54000.0 1 * -1.1.1.67 * thermotoga maritima 143000.0 4 PMID:18719905 -1.1.1.67 * thermotoga neapolitana 135000.0 2 * -1.1.1.69 * gluconacetobacter liquefaciens 110000.0 1 * -1.1.1.69 * gluconobacter oxydans 110000.0 5 PMID:15060755;PMID:19177572 -1.1.1.69 * streptococcus suis 132000.0 3 PMID:19177572 -1.1.1.71 * acinetobacter calcoaceticus 40300.0 1 PMID:8162187 -1.1.1.71 * gallus gallus 36500.0 1 PMID:11577987 -1.1.1.71 * haloarcula marismortui 41600.0 1 PMID:22015539 -1.1.1.71 * halobacterium sp. 37300.0 1 PMID:23645073 -1.1.1.71 * haloferax volcanii 132000.0 2 PMID:22526808 -1.1.1.71 * homo sapiens 37000.0 2 PMID:12435598;PMID:25451588 -1.1.1.71 * pectobacterium atrosepticum 43200.0 2 PMID:24265029 -1.1.1.71 * saccharomyces cerevisiae 43500.0 1 PMID:8162187 -1.1.1.71 * thermococcus kodakarensis 31464.0 3 PMID:23354700 -1.1.1.71 * thermococcus sibiricus 60000.0 3 PMID:20418438 -1.1.1.72 * aspergillus nidulans 38000.0 2 PMID:12823816;PMID:2200840 -1.1.1.72 * aspergillus niger 38000.0 1 PMID:2200840 -1.1.1.72 * gluconobacter oxydans 39000.0 3 PMID:19579248;PMID:20887732 -1.1.1.72 * neurospora crassa 160000.0 2 * -1.1.1.72 * oryctolagus cuniculus 34000.0 1 PMID:4400494;PMID:7144572 -1.1.1.73 * drosophila persimilis 101500.0 1 PMID:17248763 -1.1.1.73 * drosophila pseudoobscura 101500.0 1 PMID:17248763 -1.1.1.73 * drosophila sp. (in: flies) 109000.0 1 PMID:4636742 -1.1.1.73 * ogataea wickerhamii 83000.0 2 PMID:23274959 -1.1.1.75 * bacillus subtilis 250000.0 1 PMID:4334917 -1.1.1.75 * pseudomonas sp. 80000.0 1 PMID:5729604 -1.1.1.76 * bacillus licheniformis 125000.0 2 PMID:11577733;PMID:26494135 -1.1.1.76 * corynebacterium glutamicum 110000.0 7 PMID:11577733;PMID:24025762;PMID:24699738;PMID:26494135 -1.1.1.76 * mycobacterium sp. 150000.0 2 PMID:25082080 -1.1.1.76 * rhodococcus erythropolis 26864.0 1 PMID:23568047 -1.1.1.77 * escherichia coli 76000.0 2 PMID:40956 -1.1.1.77 * microcyclus eburneus 155000.0 2 * -1.1.1.78 * capra hircus 89000.0 2 PMID:6386056 -1.1.1.78 * escherichia coli 43000.0 1 * -1.1.1.78 * saccharomyces cerevisiae 43000.0 1 * -1.1.1.78 * sus scrofa 69000.0 2 * -1.1.1.79 * arabidopsis thaliana 36287.0 4 PMID:18495639 -1.1.1.79 * euglena gracilis 82000.0 1 PMID:3922357 -1.1.1.79 * neurospora crassa 110000.0 1 * -1.1.1.79 * paecilomyces sp. 'thermophila' 78000.0 2 PMID:24835102 -1.1.1.79 * pyrococcus horikoshii ot3 76500.0 2 PMID:17327673 -1.1.1.79 * saccharomyces cerevisiae 31000.0 1 PMID:383706 -1.1.1.79 * spinacia oleracea 125000.0 2 PMID:3548703 -1.1.1.79 * thermus thermophilus hb27 36000.0 1 PMID:18302405 -1.1.1.8 * apis mellifera 79500.0 5 PMID:236444 -1.1.1.8 * ceratitis capitata 72500.0 2 PMID:14695 -1.1.1.8 * chlamydomonas reinhardtii 78100.0 3 PMID:2719977 -1.1.1.8 * clonorchis sinensis 42400.0 1 PMID:21409441 -1.1.1.8 * cynomys ludovicianus 77000.0 2 PMID:22180227 -1.1.1.8 * debaryomyces hansenii 42000.0 1 PMID:1972335 -1.1.1.8 * drosophila melanogaster 67000.0 4 PMID:6768747 -1.1.1.8 * drosophila virilis 65000.0 1 PMID:6774753 -1.1.1.8 * dunaliella salina 100000.0 3 PMID:23626797 -1.1.1.8 * dunaliella viridis 77200.0 2 PMID:19551475 -1.1.1.8 * eidolon helvum 59500.0 2 PMID:12689513 -1.1.1.8 * homo sapiens 74000.0 4 PMID:3943520;PMID:7671141 -1.1.1.8 * jaculus orientalis 72000.0 3 PMID:11952153;PMID:4433563 -1.1.1.8 * leishmania mexicana 39140.0 2 PMID:10743613;PMID:27521690;PMID:8920004 -1.1.1.8 * millerozyma farinosa 40451.0 1 PMID:20014039 -1.1.1.8 * oryctolagus cuniculus 78600.0 8 PMID:195955;PMID:226146;PMID:4200180;PMID:4778280 -1.1.1.8 * pichia kudriavzevii 42695.0 1 PMID:18452539 -1.1.1.8 * rattus norvegicus 78000.0 3 PMID:11952153;PMID:4433563 -1.1.1.8 * saccharomyces cerevisiae 68000.0 3 PMID:1499720;PMID:6808861 -1.1.1.8 * spinacia oleracea 63500.0 1 PMID:39510 -1.1.1.8 * starmerella magnoliae 40000.0 1 PMID:19054133 -1.1.1.8 * sus scrofa 37742.0 1 PMID:20857217 -1.1.1.8 * trypanosoma brucei 69000.0 2 PMID:2940090;PMID:8920004 -1.1.1.8 * urocitellus richardsonii 37000.0 1 PMID:10743613;PMID:27521690 -1.1.1.80 * aspergillus fumigatus 40800.0 1 PMID:31301008 -1.1.1.80 * trichomonas vaginalis 81000.0 3 PMID:22686835 -1.1.1.81 * bos taurus 72000.0 1 PMID:4146372 -1.1.1.81 * citrullus lanatus 45000.0 1 PMID:24220768 -1.1.1.81 * methylobacterium sp. 34000.0 1 PMID:17653579 -1.1.1.81 * methylorubrum extorquens am1 71000.0 3 PMID:1657886 -1.1.1.81 * pyrococcus horikoshii ot3 76500.0 2 PMID:17327673 -1.1.1.81 * spinacia oleracea 70000.0 2 PMID:3281657 -1.1.1.82 * aeropyrum pernix 110000.0 3 PMID:19555779 -1.1.1.82 * cicer arietinum 135000.0 1 * -1.1.1.82 * echinochloa crus-galli 86700.0 5 * -1.1.1.82 * lathyrus oleraceus 163000.0 9 PMID:1472542;PMID:3341764 -1.1.1.82 * sorghum bicolor 42207.0 1 PMID:2209586 -1.1.1.82 * spinacia oleracea 57000.0 5 PMID:3948869 -1.1.1.82 * zea mays 150000.0 12 PMID:16661905;PMID:16668822;PMID:3341761;PMID:3948869 -1.1.1.83 * cereibacter sphaeroides 162000.0 3 PMID:6345505 -1.1.1.83 * pseudomonas fluorescens 175000.0 3 PMID:6778506;PMID:6781186;PMID:6804238 -1.1.1.84 * pseudomonas fluorescens 142000.0 3 PMID:6778506;PMID:99175 -1.1.1.85 * acidithiobacillus ferrooxidans 73000.0 3 PMID:8282728 -1.1.1.85 * cyberlindnera jadinii 38700.0 1 PMID:3309174 -1.1.1.85 * escherichia coli 78780.0 1 PMID:19154118 -1.1.1.85 * heyndrickxia coagulans 90000.0 4 PMID:6087910 -1.1.1.85 * methanocaldococcus jannaschii 40000.0 1 PMID:17449626 -1.1.1.85 * pseudomonas aeruginosa 50000.0 1 PMID:4310224 -1.1.1.85 * saccharomyces cerevisiae 72000.0 3 PMID:3071718;PMID:6993484 -1.1.1.85 * salmonella enterica subsp. enterica serovar typhimurium 70000.0 2 PMID:4889950 -1.1.1.85 * sulfolobus acidocaldarius 130000.0 2 PMID:27590116 -1.1.1.85 * sulfolobus sp. 360000.0 4 PMID:7557336 -1.1.1.85 * sulfurisphaera tokodaii 136000.0 3 PMID:9023199 -1.1.1.85 * thermus thermophilus 73300.0 2 PMID:17887729;PMID:19154118 -1.1.1.85 * vibrio sp. 76960.0 1 PMID:19154118 -1.1.1.86 * corynebacterium glutamicum 36100.0 1 PMID:31298526 -1.1.1.86 * escherichia coli 230000.0 4 PMID:2189496;PMID:23036858 -1.1.1.86 * hordeum vulgare 115000.0 2 PMID:12231988 -1.1.1.86 * meiothermus ruber 40000.0 2 PMID:25446654 -1.1.1.86 * mycobacterium tuberculosis 72000.0 1 PMID:26876563 -1.1.1.86 * pseudomonas aeruginosa 266000.0 1 PMID:12454481 -1.1.1.86 * saccharolobus solfataricus 440000.0 1 PMID:30921515 -1.1.1.86 * salmonella enterica subsp. enterica serovar typhimurium 220000.0 2 PMID:4388025;PMID:803501 -1.1.1.86 * spinacia oleracea 240000.0 11 PMID:2590180;PMID:9187358;PMID:9737852 -1.1.1.86 * sulfolobus acidocaldarius 70000.0 1 PMID:29739976 -1.1.1.87 * candida albicans 158000.0 3 PMID:23107040 -1.1.1.87 * deinococcus radiodurans 154000.0 2 PMID:16139794 -1.1.1.87 * saccharomyces cerevisiae 48000.0 1 PMID:4395693 -1.1.1.87 * saccharomycopsis lipolytica 48000.0 1 PMID:6759120 -1.1.1.87 * thermococcus kodakarensis 238300.0 1 PMID:27831491 -1.1.1.88 * burkholderia cenocepacia 118000.0 2 PMID:24316250 -1.1.1.88 * pseudomonas sp. 'mevalonii' 270100.0 5 PMID:2656635;PMID:4019479;PMID:7278665;PMID:9232206 -1.1.1.9 * [candida] sp. ha 167 160000.0 3 PMID:12604239;PMID:17343568 -1.1.1.9 * aeribacillus pallidus 28000.0 1 * -1.1.1.9 * aspergillus oryzae 38197.0 2 PMID:16233653 -1.1.1.9 * blastobotrys adeninivorans 80000.0 3 PMID:15803389 -1.1.1.9 * fusarium oxysporum 94000.0 2 * -1.1.1.9 * gluconobacter oxydans 29000.0 3 PMID:12723607;PMID:26975753 -1.1.1.9 * meyerozyma caribbica 195000.0 1 PMID:27506274 -1.1.1.9 * morganella morganii 142000.0 1 PMID:3886639 -1.1.1.9 * pachysolen tannophilus 172000.0 5 PMID:16347161 -1.1.1.9 * providencia stuartii 155000.0 1 PMID:3886639 -1.1.1.9 * rhizobium etli 135000.0 3 PMID:20177886 -1.1.1.9 * rhizomucor pusillus 87000.0 1 PMID:25082263 -1.1.1.9 * scheffersomyces shehatae 82000.0 2 * -1.1.1.9 * scheffersomyces stipitis 40000.0 1 PMID:25363139 -1.1.1.9 * serratia marcescens 130000.0 1 PMID:3886639 -1.1.1.90 * acinetobacter baylyi 72600.0 2 PMID:23042182 -1.1.1.90 * acinetobacter calcoaceticus 155000.0 2 PMID:3291854 -1.1.1.90 * lactiplantibacillus plantarum wcfs1 40000.0 1 PMID:18510336 -1.1.1.90 * phanerodontia chrysosporium 43000.0 1 PMID:16217726 -1.1.1.90 * pseudomonas putida 145000.0 8 PMID:2202600;PMID:743216;PMID:8496150 -1.1.1.90 * rhodoblastus acidophilus 27000.0 1 * -1.1.1.90 * streptomyces sp. 151000.0 3 PMID:21897026;PMID:23500723 -1.1.1.90 * thauera sp. 160000.0 2 PMID:7575097 -1.1.1.90 * yokenella sp. wzy002 36411.0 1 PMID:24509923 -1.1.1.91 * neurospora crassa 75000.0 1 PMID:24509923;PMID:4389864 -1.1.1.91 * phanerodontia chrysosporium 280000.0 3 PMID:1997322;PMID:22742413 -1.1.1.91 * saccharum officinarum 48000.0 1 * -1.1.1.91 * taiwanofungus camphoratus 40580.0 2 * -1.1.1.91 * yokenella sp. wzy002 75000.0 3 PMID:24509923;PMID:4389864 -1.1.1.92 * pseudomonas putida 63000.0 1 PMID:4385076 -1.1.1.93 * cereibacter sphaeroides 162000.0 3 PMID:6345505 -1.1.1.93 * pseudomonas putida 145000.0 5 PMID:2184888;PMID:4297261;PMID:8053675 -1.1.1.94 * escherichia coli k-12 50700.0 2 PMID:355254 -1.1.1.94 * rickettsia prowazekii 36600.0 1 PMID:20581209 -1.1.1.95 * acanthamoeba castellanii 50000.0 2 PMID:25622549 -1.1.1.95 * aphanothece halophytica 57000.0 2 PMID:17884813 -1.1.1.95 * arabidopsis thaliana 66453.0 4 PMID:28615699;PMID:30061906;PMID:9867856 -1.1.1.95 * bacillus subtilis 207300.0 3 PMID:168067;PMID:25698123 -1.1.1.95 * corynebacterium glutamicum 207300.0 2 PMID:25698123 -1.1.1.95 * entamoeba histolytica 74000.0 5 PMID:15206932;PMID:22057349;PMID:25944370 -1.1.1.95 * escherichia coli 165000.0 3 PMID:4384871;PMID:7719856;PMID:8771194 -1.1.1.95 * gallus gallus 165000.0 1 PMID:564905 -1.1.1.95 * glycine max 250000.0 1 PMID:16662883 -1.1.1.95 * homo sapiens 207300.0 3 PMID:19235232;PMID:25698123 -1.1.1.95 * marchantia polymorpha 60000.0 1 PMID:28615699;PMID:30061906 -1.1.1.95 * mus musculus 57000.0 1 PMID:18751891 -1.1.1.95 * mycobacterium marinum 207300.0 1 PMID:25698123 -1.1.1.95 * mycobacterium tuberculosis 207300.0 2 PMID:15668250;PMID:25698123 -1.1.1.95 * mycolicibacterium smegmatis 207300.0 1 PMID:25698123 -1.1.1.95 * oryctolagus cuniculus 247000.0 2 PMID:3800969 -1.1.1.95 * streptomyces coelicolor 207300.0 2 PMID:25698123 -1.1.1.95 * sulfurisphaera tokodaii 35000.0 1 PMID:18054776 -1.1.1.97 * penicillium urticae 120000.0 2 PMID:3516352;PMID:4335290 -1.1.2.10 * bradyrhizobium diazoefficiens 136000.0 1 PMID:31421721 -1.1.2.10 * candidatus methylacidiphilum fumarolicum 127000.0 1 PMID:24034209 -1.1.2.10 * methylobacterium radiotolerans 120000.0 1 PMID:21256798 -1.1.2.10 * methylomonas sp. lw13 127900.0 1 PMID:29997591 -1.1.2.10 * methylorubrum extorquens 126400.0 2 PMID:23209751;PMID:27573017 -1.1.2.10 * methylotenera mobilis 131700.0 2 PMID:29997591 -1.1.2.11 * halomonas sp. 67000.0 1 PMID:15304701 -1.1.2.2 * komagataeibacter xylinus 140000.0 4 * -1.1.2.3 * rhodovulum steppense 140000.0 1 * -1.1.2.3 * saccharomyces cerevisiae 235000.0 11 PMID:10727218;PMID:11914072;PMID:1567382;PMID:19850002;PMID:362125;PMID:4575975;PMID:4593578;PMID:7626026;PMID:8547270 -1.1.2.3 * stutzerimonas stutzeri 45390.0 1 PMID:17091386 -1.1.2.3 * wickerhamomyces anomalus 220000.0 5 PMID:2688640;PMID:362125;PMID:697031 -1.1.2.4 * arabidopsis thaliana 135000.0 3 PMID:19586914;PMID:27506242 -1.1.2.4 * megasphaera elsdenii 125000.0 3 PMID:236453;PMID:497162 -1.1.2.4 * rhodopseudomonas palustris 235000.0 2 PMID:15056881 -1.1.2.4 * saccharomyces cerevisiae 100000.0 1 * -1.1.2.6 * pseudomonas sp. 68045.0 2 PMID:8782398 -1.1.2.7 * hyphomicrobium denitrificans 148000.0 5 PMID:16533029 -1.1.2.7 * methylophaga aminisulfidivorans 145000.0 12 PMID:21656818;PMID:28295618;PMID:32627749 -1.1.2.7 * methylophilus methylotrophus 138000.0 3 PMID:1331050;PMID:17149777 -1.1.2.7 * methylorubrum extorquens 66000.0 5 PMID:15234264;PMID:16139516;PMID:7772016 -1.1.2.7 * methylosinus sp. 140000.0 2 PMID:9726124 -1.1.2.8 * gluconacetobacter diazotrophicus 345000.0 8 PMID:22188488 -1.1.2.8 * methylorubrum extorquens 126400.0 1 PMID:27573017 -1.1.2.8 * pseudomonas aeruginosa 136000.0 5 PMID:8382472;PMID:9826187 -1.1.2.9 * thauera butanivorans 70900.0 4 PMID:11238982;PMID:11889098 -1.1.3.10 * aspergillus nidulans 65000.0 1 PMID:21968652;PMID:25296188 -1.1.3.10 * aspergillus oryzae 65000.0 1 PMID:21968652;PMID:25296188 -1.1.3.10 * basidiomycota 300000.0 2 * -1.1.3.10 * gloeophyllum trabeum 72000.0 1 PMID:19343506 -1.1.3.10 * irpex lacteus 266000.0 2 * -1.1.3.10 * lyophyllum shimeji 68490.0 2 PMID:20630076 -1.1.3.10 * phanerodontia chrysosporium 250000.0 5 PMID:15466516;PMID:19501263;PMID:9210340 -1.1.3.10 * phlebiopsis gigantea 323600.0 8 PMID:16535364;PMID:8319689 -1.1.3.10 * pseudarthrobacter siccitolerans 66000.0 3 * -1.1.3.10 * trametes ochracea 278000.0 8 PMID:11472941;PMID:20528921;PMID:21968652;PMID:25296188;PMID:26828796 -1.1.3.10 * trametes versicolor 290000.0 4 PMID:11152063 -1.1.3.10 * tricholoma matsutake 250000.0 2 PMID:14730138 -1.1.3.12 * mesorhizobium loti 55000.0 4 PMID:15135526;PMID:23578136 -1.1.3.12 * microbacterium luteolum 54000.0 3 PMID:12092811;PMID:23578136 -1.1.3.13 * [candida] boidinii 600000.0 3 PMID:16169288;PMID:20367612 -1.1.3.13 * [candida] methanosorbosa 620000.0 2 PMID:16545060;PMID:9142745 -1.1.3.13 * [candida] sp. 520000.0 2 * -1.1.3.13 * aspergillus ochraceus 262000.0 2 PMID:17726298 -1.1.3.13 * aspergillus terreus 272000.0 8 PMID:16547701;PMID:18639656;PMID:19060312 -1.1.3.13 * basidiomycota 300000.0 1 PMID:5636370 -1.1.3.13 * comamonas sp. 66000.0 1 * -1.1.3.13 * fulvia fulva 600000.0 1 PMID:16169288 -1.1.3.13 * gloeophyllum trabeum 628000.0 2 PMID:17660304 -1.1.3.13 * komagataella pastoris 675000.0 5 PMID:16169288;PMID:16545060;PMID:23242497;PMID:23968724;PMID:9142745 -1.1.3.13 * ochrobactrum sp. 130000.0 3 * -1.1.3.13 * ogataea angusta 620000.0 4 PMID:16169288;PMID:16545060;PMID:2280715;PMID:9142745 -1.1.3.13 * ogataea methanolica 600000.0 1 PMID:16169288 -1.1.3.13 * ogataea pini 600000.0 1 PMID:16169288 -1.1.3.13 * paecilomyces variotii 450000.0 2 PMID:17985128 -1.1.3.13 * penicillium chrysogenum 600000.0 1 PMID:16169288 -1.1.3.13 * penicillium purpurescens 260000.0 2 PMID:19217545 -1.1.3.13 * phanerodontia chrysosporium 310000.0 4 PMID:24910330 -1.1.3.13 * phlebiopsis gigantea 576000.0 2 * -1.1.3.13 * pichia putida 590000.0 3 PMID:20367612 -1.1.3.13 * pichia sp. 300000.0 2 PMID:7030206 -1.1.3.13 * poria contigua 610000.0 2 PMID:118005 -1.1.3.13 * thermoascus aurantiacus 560000.0 2 PMID:16233800 -1.1.3.15 * aerococcus viridans 187300.0 3 PMID:11916135;PMID:12052088;PMID:8589073 -1.1.3.15 * amaranthus retroflexus 44000.0 2 * -1.1.3.15 * candidatus caldarchaeum subterraneum 114000.0 1 PMID:29691195 -1.1.3.15 * gallus gallus 169000.0 2 PMID:2194838 -1.1.3.15 * geotrichum candidum 400000.0 2 PMID:8766696 -1.1.3.15 * homo sapiens 45290.0 2 PMID:17669354 -1.1.3.15 * lactococcus lactis 40950.0 2 PMID:17557814;PMID:17993525 -1.1.3.15 * mus musculus 40000.0 1 PMID:1261544 -1.1.3.15 * nicotiana benthamiana 160000.0 1 PMID:30143257 -1.1.3.15 * rattus norvegicus 39000.0 1 PMID:24900281 -1.1.3.15 * rattus sp. 300000.0 7 PMID:1148170;PMID:1261544;PMID:1268224;PMID:5686300;PMID:5946631 -1.1.3.15 * streptococcus iniae 44040.0 4 PMID:19270123 -1.1.3.15 * sus scrofa 51100.0 1 PMID:5569122 -1.1.3.15 * zea mays 160000.0 2 * -1.1.3.16 * bombyx mori 72000.0 1 PMID:22215981 -1.1.3.16 * calliphora vicina 240000.0 1 PMID:297 -1.1.3.16 * spodoptera littoralis 190000.0 3 PMID:11373299 -1.1.3.17 * alcaligenes sp. 120000.0 4 PMID:18769736;PMID:25167196;PMID:6997283 -1.1.3.17 * arthrobacter globiformis 122000.0 7 PMID:14678796;PMID:19053234;PMID:435313;PMID:599154 -1.1.3.17 * cylindrocarpon didymum 145000.0 3 PMID:23221722 -1.1.3.17 * fusarium oxysporum 128000.0 2 PMID:23221722 -1.1.3.18 * bacteria 50000.0 4 * -1.1.3.18 * brevundimonas vesicularis 85000.0 2 * -1.1.3.18 * pseudomonas sp. 50500.0 4 * -1.1.3.19 * pseudomonas putida 155000.0 1 PMID:976259 -1.1.3.2 * aerococcus viridans 187000.0 3 PMID:11916135;PMID:2818595;PMID:8589073 -1.1.3.2 * gram-negative soil bacterium 204000.0 2 PMID:8984900 -1.1.3.2 * yarrowia lipolytica 230000.0 1 PMID:29509375 -1.1.3.20 * [candida] cloacae 77300.0 2 PMID:10660617 -1.1.3.20 * arabidopsis thaliana 73000.0 1 PMID:15358540 -1.1.3.20 * aspergillus terreus 272000.0 1 PMID:16547701 -1.1.3.20 * candida tropicalis 145000.0 2 PMID:1546949 -1.1.3.20 * mucor circinelloides 350000.0 2 PMID:19642009 -1.1.3.20 * starmerella bombicola 75000.0 1 PMID:27383605 -1.1.3.20 * tanacetum vulgare 180000.0 3 * -1.1.3.21 * aerococcus viridans 63000.0 1 PMID:11759680 -1.1.3.21 * enterococcus faecium 131000.0 4 PMID:3771536;PMID:429313 -1.1.3.21 * mycoplasma mycoides 47000.0 1 PMID:24035434 -1.1.3.21 * mycoplasma mycoides subsp. mycoides 90000.0 3 PMID:16166545;PMID:19364458 -1.1.3.21 * streptococcus pneumoniae 65000.0 1 PMID:25556096 -1.1.3.23 * unidentified soil bacterium 52000.0 2 PMID:468775;PMID:4987737 -1.1.3.28 * stenotrophomonas maltophilia 130000.0 5 * -1.1.3.29 * pseudomonas sp. 170000.0 5 * -1.1.3.30 * brevundimonas vesicularis 85000.0 2 * -1.1.3.30 * priestia megaterium 134300.0 1 * -1.1.3.30 * pseudomonas sp. 31000.0 1 PMID:3513704 -1.1.3.30 * sphingopyxis sp. 68000.0 1 PMID:16804170 -1.1.3.37 * candida albicans 110000.0 3 PMID:8841374 -1.1.3.37 * leishmania donovani 57000.0 1 PMID:21907739 -1.1.3.38 * penicillium simplicissimum 520000.0 11 PMID:12107187;PMID:1396672;PMID:18793324;PMID:27214042;PMID:9525880 -1.1.3.38 * rhodococcus jostii 111000.0 1 PMID:17419730 -1.1.3.39 * elizabethkingia meningoseptica 500000.0 5 PMID:16535726 -1.1.3.4 * aspergillus niger 669000.0 32 PMID:12093294;PMID:1213991;PMID:12716878;PMID:182278;PMID:18330562;PMID:1932088;PMID:19374943;PMID:19784554;PMID:21040747;PMID:23540931;PMID:23562736;PMID:24122283;PMID:24283586;PMID:2511903;PMID:26642312;PMID:28631058;PMID:30197862;PMID:8987726 -1.1.3.4 * aspergillus tubingensis 180000.0 1 PMID:26280215 -1.1.3.4 * cladosporium neopsychrotolerans 64600.0 1 PMID:31838375 -1.1.3.4 * goffeauzyma gastrica 91000.0 1 PMID:29312954 -1.1.3.4 * helicoverpa armigera 67000.0 1 PMID:22392771 -1.1.3.4 * penicillium amagasakiense 176000.0 13 PMID:10749686;PMID:21040747;PMID:5577148;PMID:9210339;PMID:9546178 -1.1.3.4 * penicillium chrysogenum 180000.0 2 PMID:3116021;PMID:3226296;PMID:3957868 -1.1.3.4 * penicillium expansum 130000.0 1 * -1.1.3.4 * penicillium sp. 148000.0 2 PMID:17084642 -1.1.3.4 * phanerodontia chrysosporium 180000.0 3 PMID:3116021;PMID:3226296;PMID:3957868 -1.1.3.4 * pleurotus ostreatus 290000.0 2 PMID:8354282 -1.1.3.4 * spodoptera exigua 70000.0 1 PMID:20688075 -1.1.3.4 * streptomyces coelicolor 45100.0 1 PMID:19224207 -1.1.3.4 * talaromyces pinophilus 160000.0 5 * -1.1.3.4 * talaromyces variabilis 175000.0 4 * -1.1.3.41 * acidothermus cellulolyticus 47000.0 2 PMID:22231860 -1.1.3.41 * streptomyces coelicolor 47000.0 2 PMID:19224207;PMID:22231860 -1.1.3.41 * streptomyces sp. 43000.0 1 PMID:16232758 -1.1.3.42 * alternaria solani 62000.0 3 PMID:18256508;PMID:9659400 -1.1.3.43 * streptomyces fradiae 60034.0 1 PMID:17206729 -1.1.3.44 * streptomyces fradiae 60034.0 1 PMID:17206729 -1.1.3.45 * streptomyces peucetius 54000.0 1 * -1.1.3.46 * amycolatopsis orientalis 39864.0 2 PMID:12240298 -1.1.3.46 * streptomyces coelicolor 38200.0 1 PMID:25713978 -1.1.3.47 * methylovorus sp. mp688 70000.0 1 PMID:24271187 -1.1.3.49 * chamberlinius hualienensis 67000.0 2 PMID:27265180 -1.1.3.5 * chondrus crispus 130000.0 5 PMID:11427234;PMID:9108257;PMID:9111074 -1.1.3.50 * microbacterium sp. 5-2b 54900.0 1 PMID:34583991 -1.1.3.6 * arthrobacter sp. 63000.0 1 PMID:19495743 -1.1.3.6 * bacillus sp. (in: firmicutes) 37000.0 2 * -1.1.3.6 * bacillus subtilis 105000.0 1 PMID:26453032 -1.1.3.6 * bordetella sp. 55000.0 1 PMID:17379143;PMID:21909628 -1.1.3.6 * brevibacterium sterolicum 55000.0 5 PMID:12399041;PMID:19495743;PMID:9428686 -1.1.3.6 * burkholderia cepacia 60000.0 1 PMID:19495743 -1.1.3.6 * castellaniella sp. 59000.0 1 PMID:31750957 -1.1.3.6 * chromobacterium sp. 58000.0 1 PMID:19495743 -1.1.3.6 * chryseobacterium gleum 85000.0 1 PMID:24885249 -1.1.3.6 * corynebacterium cholesterolicum 57000.0 1 PMID:19495743 -1.1.3.6 * gamma proteobacterium y-134 58000.0 1 PMID:16233518 -1.1.3.6 * mycolicibacterium neoaurum 64300.0 3 PMID:23164577 -1.1.3.6 * pimelobacter simplex 57000.0 1 PMID:19495743 -1.1.3.6 * pleurotus ostreatus 50000.0 1 * -1.1.3.6 * prescottella equi 60000.0 1 PMID:10822008 -1.1.3.6 * pseudomonas sp. 65100.0 2 * -1.1.3.6 * rhodococcus sp. (in: high g+c gram-positive bacteria) 63300.0 2 PMID:20630728 -1.1.3.6 * schizophyllum commune 53000.0 1 PMID:36375 -1.1.3.6 * streptomyces aegyptia 46000.0 1 PMID:28356065 -1.1.3.6 * streptomyces fradiae 60000.0 1 PMID:19495743 -1.1.3.6 * streptomyces hygroscopicus 53000.0 2 PMID:9428686 -1.1.3.6 * streptomyces natalensis 55000.0 1 PMID:17379143;PMID:21909628 -1.1.3.6 * streptomyces parvus 55000.0 1 PMID:17379143;PMID:21909628 -1.1.3.6 * streptomyces sp. 62000.0 3 PMID:19495743;PMID:23700127 -1.1.3.6 * streptomyces sp. akhss 48000.0 2 * -1.1.3.6 * streptomyces violascens 30000.0 1 PMID:956143 -1.1.3.6 * streptomyces virginiae 59000.0 2 PMID:19711070 -1.1.3.6 * streptoverticillium cholesterolieum 56000.0 1 PMID:19495743 -1.1.3.6 * uncultured gammaproteobacteria bacterium 58000.0 1 PMID:19495743 -1.1.3.7 * aspergillus terreus 272000.0 2 PMID:16547701;PMID:24752075 -1.1.3.7 * chrysomela populi 80000.0 4 PMID:12530219;PMID:18482980 -1.1.3.7 * chrysomela tremula 80000.0 3 PMID:18482980 -1.1.3.7 * lentinus sajor-caju 71000.0 1 PMID:3060110 -1.1.3.7 * phanerodontia chrysosporium 78000.0 1 * -1.1.3.7 * phratora vitellinae 334000.0 2 PMID:12530219 -1.1.3.7 * pleurotus eryngii 100000.0 10 PMID:10606774;PMID:11257513;PMID:1425667;PMID:16039872;PMID:16999821;PMID:32949280 -1.1.3.7 * pleurotus ostreatus 72000.0 3 PMID:20857231 -1.1.3.7 * pleurotus pulmonarius 70500.0 2 PMID:10606774;PMID:11257513 -1.1.3.7 * pleurotus sapidus 73000.0 2 PMID:27138199 -1.1.3.7 * sphingobacterium sp. 71000.0 1 PMID:3060110 -1.1.3.7 * thermothelomyces thermophilus 79500.0 1 PMID:32653619 -1.1.3.8 * acipenser transmontanus 50529.0 1 * -1.1.3.8 * capra hircus 500000.0 2 PMID:440104;PMID:822334 -1.1.3.8 * gallus gallus 400000.0 2 PMID:7138847 -1.1.3.8 * gluconobacter oxydans 110000.0 4 * -1.1.3.8 * grifola frondosa 250000.0 1 PMID:11575583 -1.1.3.8 * mustelus manazo 51405.0 1 * -1.1.3.8 * pelodiscus sinensis 50600.0 1 * -1.1.3.8 * rattus norvegicus 500000.0 7 PMID:3338984;PMID:440104;PMID:5484453;PMID:5769996;PMID:822334;PMID:8459881;PMID:9211253 -1.1.3.8 * scyliorhinus torazame 50976.0 1 * -1.1.3.8 * triakis scyllium 51217.0 1 * -1.1.3.9 * fusarium acuminatum 66000.0 1 PMID:17518413 -1.1.3.9 * fusarium fujikuroi 90000.0 1 * -1.1.3.9 * fusarium graminearum 68500.0 1 PMID:18771294 -1.1.3.9 * fusarium sp. 68527.0 2 PMID:15047910;PMID:20000571;PMID:7929198 -1.1.3.9 * hypomyces rosellus 72000.0 9 PMID:11401560;PMID:17518413;PMID:19998406;PMID:20000571;PMID:2408573;PMID:3377508;PMID:3813549;PMID:4441089;PMID:6890617;PMID:7929198 -1.1.3.9 * paenibacillus sp. 24000.0 1 PMID:20547358 -1.1.3.9 * paenibacillus sp. aiu 311 49000.0 2 PMID:17884657 -1.1.3.9 * polyporus circinatus 42400.0 2 PMID:5752801 -1.1.5.10 * oryctolagus cuniculus 102000.0 2 PMID:5359443 -1.1.5.10 * pseudomonas putida 118000.0 1 PMID:28847921 -1.1.5.11 * thauera butanivorans 67553.0 1 PMID:11889098 -1.1.5.12 * escherichia coli 75000.0 3 PMID:369600;PMID:4575624;PMID:4582730 -1.1.5.12 * pseudomonas putida kt2440 118000.0 1 PMID:28847921 -1.1.5.14 * gluconobacter japonicus 146400.0 13 PMID:23275508;PMID:27213223;PMID:29564502;PMID:30148350;PMID:31063949 -1.1.5.14 * gluconobacter oxydans 140000.0 4 PMID:27213223;PMID:7462161 -1.1.5.14 * gluconobacter sp. 140000.0 1 * -1.1.5.2 * acinetobacter calcoaceticus 110000.0 14 PMID:14741705;PMID:14982451;PMID:15571780;PMID:16944137;PMID:18029757;PMID:2549865;PMID:2551369;PMID:32247165;PMID:3800975 -1.1.5.2 * arthrobacter globiformis 87000.0 1 PMID:25580683 -1.1.5.2 * escherichia coli 90000.0 2 PMID:16864586;PMID:20215780 -1.1.5.2 * gluconacetobacter diazotrophicus 87000.0 2 PMID:25576305;PMID:32247165 -1.1.5.2 * gluconobacter oxydans 89000.0 2 PMID:22790543 -1.1.5.2 * pseudomonas fluorescens 93000.0 2 * -1.1.5.2 * pyrobaculum aerophilum 40000.0 4 PMID:20692227 -1.1.5.2 * sorangium cellulosum 63000.0 2 PMID:20886312 -1.1.5.2 * thermus thermophilus 80000.0 3 PMID:27592307 -1.1.5.3 * arabidopsis thaliana 68000.0 1 PMID:12586344 -1.1.5.3 * cyberlindnera jadinii 520000.0 1 PMID:6817793 -1.1.5.3 * escherichia coli 130000.0 7 PMID:340460;PMID:4557172;PMID:6792201 -1.1.5.3 * giardia duodenalis 120000.0 2 PMID:26082764 -1.1.5.3 * homo sapiens 140000.0 1 PMID:32717855 -1.1.5.3 * mus musculus 80000.0 1 PMID:20602492 -1.1.5.3 * rattus norvegicus 74000.0 1 PMID:23220394 -1.1.5.3 * sus scrofa 75000.0 1 PMID:6796038 -1.1.5.3 * vibrio alginolyticus 300000.0 1 PMID:6796567 -1.1.5.4 * bacillus sp. (in: firmicutes) 92000.0 2 PMID:23143325 -1.1.5.4 * mycobacterium sp. 55000.0 1 PMID:629992 -1.1.5.4 * mycolicibacterium phlei 164000.0 3 * -1.1.5.4 * pseudomonas taetrolens 54000.0 1 PMID:33166455 -1.1.5.5 * acetobacter lovaniensis 72000.0 3 PMID:20306188 -1.1.5.5 * acetobacter pasteurianus 76000.0 12 PMID:16133326;PMID:20306188 -1.1.5.5 * acetobacter sp. 78000.0 3 PMID:16636451 -1.1.5.5 * acidomonas methanolica 80000.0 3 PMID:20306188 -1.1.5.5 * frateuria aurantia 72000.0 2 PMID:16133326;PMID:23760531 -1.1.5.5 * gluconacetobacter diazotrophicus 115000.0 7 PMID:18321602;PMID:20148520;PMID:20306188 -1.1.5.5 * gluconacetobacter polyoxogenes 72000.0 2 PMID:20306188 -1.1.5.5 * gluconobacter oxydans 85000.0 5 PMID:20306188 -1.1.5.5 * gluconobacter sp. 145000.0 4 * -1.1.5.5 * komagataeibacter europaeus 72000.0 4 PMID:16133326;PMID:20306188;PMID:23760531 -1.1.5.5 * komagataeibacter intermedius 72000.0 4 PMID:16133326;PMID:20306188;PMID:23760531 -1.1.5.5 * komagataeibacter xylinus 119000.0 5 PMID:20306188;PMID:20559622 -1.1.5.7 * gluconobacter frateurii 83000.0 1 PMID:11826975 -1.1.5.8 * acinetobacter calcoaceticus 88000.0 1 PMID:14586098 -1.1.5.8 * gluconobacter oxydans 86000.0 1 PMID:20618134 -1.1.5.9 * acinetobacter baumannii 86000.0 1 PMID:14257587 -1.1.5.9 * aspergillus flavus 61600.0 2 PMID:25650345;PMID:27510979;PMID:27573296 -1.1.5.9 * aspergillus niger 60000.0 1 PMID:25650345;PMID:27510979;PMID:27573296 -1.1.5.9 * aspergillus oryzae 120000.0 2 PMID:6034674 -1.1.5.9 * aspergillus sp. 97000.0 2 PMID:22222911 -1.1.5.9 * burkholderia cepacia 380000.0 14 PMID:15604831;PMID:23695009 -1.1.5.9 * colletotrichum gloeosporioides 135000.0 4 PMID:21903757;PMID:22151971;PMID:22222911 -1.1.5.9 * komagataella pastoris 131000.0 1 PMID:22222911 -1.1.5.9 * mucor circinelloides 80000.0 1 PMID:25912449 -1.1.5.9 * pseudomonas sp. 93000.0 2 * -1.1.5.9 * rasamsonia emersonii 60000.0 1 PMID:25650345;PMID:27510979;PMID:27573296 -1.1.5.9 * thermoascus crustaceus 58000.0 1 PMID:27510979 -1.1.7.1 * pseudomonas sp. 260000.0 4 PMID:8477729;PMID:9057820 -1.1.7.1 * thauera aromatica 270000.0 8 PMID:15721605;PMID:16218872;PMID:18393440;PMID:8477729;PMID:9057820;PMID:9490068 -1.1.9.1 * comamonas testosteroni 73200.0 4 PMID:3521592;PMID:7601151 -1.1.9.1 * pseudomonas putida 73262.0 4 PMID:11515547;PMID:7730276 -1.1.98.2 * mycobacterium tuberculosis 75000.0 2 PMID:23110042 -1.1.98.2 * mycolicibacterium smegmatis 78000.0 2 PMID:8631674 -1.1.98.3 * mycolicibacterium smegmatis 44000.0 1 PMID:23184707 -1.1.98.4 * archaeoglobus fulgidus 270000.0 9 PMID:10971593;PMID:8055920 -1.1.98.4 * methanosarcina mazei gö1 115000.0 6 * -1.1.98.5 * methanoculleus thermophilus 100000.0 3 * -1.1.98.5 * methanofollis liminatans 150000.0 2 PMID:1879431 -1.1.98.6 * escherichia coli 145000.0 4 PMID:1460049;PMID:8621608 -1.1.98.6 * lactococcus cremoris 84100.0 1 PMID:11427536 -1.1.98.7 * clostridium perfringens 45740.0 1 PMID:23477283 -1.1.99.1 * escherichia coli 61848.0 2 * -1.1.99.1 * nicotiana tabacum 62000.0 1 PMID:10938824 -1.1.99.1 * pseudomonas aeruginosa 145000.0 3 PMID:406917;PMID:7765090 -1.1.99.12 * gluconobacter oxydans 190000.0 7 PMID:9023923 -1.1.99.13 * agaricus bisporus 57000.0 2 * -1.1.99.13 * agrobacterium tumefaciens 85000.0 4 PMID:165382 -1.1.99.13 * flavobacterium saccharophilum 270000.0 4 PMID:3818559 -1.1.99.13 * sphingobacterium faecium 63500.0 3 PMID:24585380;PMID:28044272 -1.1.99.14 * trichoderma harzianum 280000.0 5 * -1.1.99.18 * agroathelia rolfsii 126000.0 9 PMID:11282631;PMID:16787264;PMID:17373647 -1.1.99.18 * amesia atrobrunnea 90000.0 2 PMID:21216904 -1.1.99.18 * aspergillus fumigatus 83100.0 1 PMID:16787264 -1.1.99.18 * aspergillus nidulans 81500.0 1 PMID:16787264 -1.1.99.18 * cerrena unicolor 97000.0 2 PMID:26003328;PMID:29418014 -1.1.99.18 * chaetomium sp. 95000.0 1 PMID:16112765 -1.1.99.18 * coniophora puteana 115000.0 1 PMID:16787264 -1.1.99.18 * coniophora puteana (schum ex fr) karsten 192000.0 2 PMID:8434937 -1.1.99.18 * coprinopsis cinerea 83000.0 1 PMID:22940800 -1.1.99.18 * dichomera saubinetii 115000.0 2 PMID:21216904 -1.1.99.18 * fusarium graminearum 85900.0 1 PMID:16787264 -1.1.99.18 * gelatoporia subvermispora 84000.0 1 PMID:19270118 -1.1.99.18 * grifola frondosa 79600.0 1 PMID:16787264 -1.1.99.18 * hypoxylon haematostroma 85000.0 2 PMID:21216904 -1.1.99.18 * irpex lacteus 97000.0 1 PMID:16787264 -1.1.99.18 * meruliella lindtneri 104500.0 1 * -1.1.99.18 * monilia sitophila 48000.0 1 * -1.1.99.18 * mycothermus thermophilus 92000.0 2 PMID:16787264;PMID:9461557 -1.1.99.18 * neurospora crassa 130000.0 14 PMID:16787264;PMID:20709172;PMID:21216904;PMID:22729546 -1.1.99.18 * phanerochaete sordida 88000.0 1 * -1.1.99.18 * phanerodontia chrysosporium 110000.0 13 PMID:11676020;PMID:14666391;PMID:16787264;PMID:20120044;PMID:21216904;PMID:24929309;PMID:27199949;PMID:2992449;PMID:710416;PMID:7144569;PMID:8434950 -1.1.99.18 * podospora anserina 83000.0 1 PMID:22940800 -1.1.99.18 * pyricularia grisea 87000.0 1 PMID:16787264 -1.1.99.18 * schizophyllum commune 102000.0 1 PMID:9578598 -1.1.99.18 * stachybotrys bisbyi 100000.0 2 PMID:21216904;PMID:24929309 -1.1.99.18 * termitomyces clypeatus 101000.0 2 * -1.1.99.18 * termitomyces sp. 100000.0 1 PMID:21216904;PMID:24929309 -1.1.99.18 * thermothelomyces fergusii 85000.0 3 PMID:21216904;PMID:28245812 -1.1.99.18 * thermothelomyces heterothallicus 95000.0 1 PMID:10328816 -1.1.99.18 * thermothelomyces myriococcoides 100000.0 3 PMID:18374601;PMID:25862501 -1.1.99.18 * thermothielavioides terrestris 125000.0 1 PMID:22484439 -1.1.99.18 * trametes cinnabarina 92000.0 2 PMID:16787264 -1.1.99.18 * trametes hirsuta 91700.0 1 PMID:16861797 -1.1.99.18 * trametes pubescens 100000.0 3 PMID:14666391;PMID:18374601;PMID:8434950 -1.1.99.18 * trametes sanguinea 113400.0 1 PMID:24315647 -1.1.99.18 * trametes versicolor 98000.0 3 PMID:16787264 -1.1.99.18 * trametes villosa 98000.0 4 PMID:14666391 -1.1.99.2 * alcaligenes sp. 48000.0 2 * -1.1.99.2 * arabidopsis thaliana 46000.0 1 PMID:26203119 -1.1.99.20 * flavobacterium sp. 240000.0 4 PMID:6999995 -1.1.99.20 * pseudomonas sp. 240000.0 2 PMID:6999995 -1.1.99.20 * rhodoblastus acidophilus 72000.0 1 * -1.1.99.20 * sphingopyxis terrae 120000.0 2 PMID:11673442 -1.1.99.21 * gluconobacter oxydans 131000.0 7 PMID:18502922;PMID:27633501 -1.1.99.24 * bemisia tabaci 51816.0 1 PMID:28117358 -1.1.99.24 * rattus norvegicus 55000.0 3 PMID:16616524 -1.1.99.27 * nocardia asteroides 600000.0 2 PMID:1541293 -1.1.99.28 * zymomonas mobilis 300000.0 7 PMID:1537789;PMID:3745122;PMID:7756998;PMID:8472911 -1.1.99.29 * agaricus bisporus 79000.0 2 PMID:24970179;PMID:25043975;PMID:9042751 -1.1.99.29 * agaricus campestris 98000.0 2 PMID:24970179 -1.1.99.29 * agaricus xanthodermus 75000.0 4 PMID:17227387;PMID:19768457;PMID:24970179;PMID:25043975;PMID:9042751 -1.1.99.29 * chlorophyllum rhacodes 78000.0 3 PMID:11511865;PMID:19768457 -1.1.99.29 * macropsalliota meleagris 93000.0 13 PMID:18083263;PMID:19768457;PMID:19888575;PMID:22080342;PMID:24614932;PMID:24970179;PMID:25043975;PMID:26284701;PMID:27995309;PMID:28193332;PMID:9042751 -1.1.99.3 * campylobacter jejuni 63700.0 2 PMID:18284594 -1.1.99.3 * gluconobacter oxydans 64000.0 3 * -1.1.99.3 * klebsiella pneumoniae 66000.0 3 PMID:6815420 -1.1.99.3 * pantoea cypripedii 68000.0 3 PMID:9352901 -1.1.99.3 * pseudomonas aeruginosa 138000.0 5 PMID:109426 -1.1.99.3 * pseudomonas fluorescens 66500.0 3 PMID:6815420 -1.1.99.3 * serratia marcescens 136000.0 4 * -1.1.99.30 * proteus vulgaris 750000.0 6 PMID:8026480 -1.1.99.32 * gluconobacter oxydans 210000.0 2 * -1.1.99.32 * ketogulonicigenium vulgare 117200.0 1 PMID:24557074 -1.1.99.32 * sinorhizobium sp. 150000.0 2 PMID:25721692 -1.1.99.35 * acinetobacter calcoaceticus 50000.0 2 PMID:21036156 -1.1.99.36 * amycolatopsis methanolica 120000.0 6 PMID:12827287;PMID:8385013 -1.1.99.37 * bacillus methanolicus 43000.0 1 PMID:12351635 -1.1.99.37 * bacillus sp. (in: firmicutes) 363000.0 2 PMID:1995642 -1.1.99.37 * mycobacterium sp. 46223.0 2 PMID:19875438 -1.1.99.39 * arabidopsis thaliana 61450.0 1 PMID:19586914 -1.1.99.4 * gluconobacter oxydans 61000.0 3 * -1.1.99.42 * mesorhizobium loti 59100.0 3 PMID:18216065;PMID:19218190 -1.1.99.42 * pseudomonas sp. ma-1 65000.0 3 PMID:3533936;PMID:6348042 -1.1.99.6 * candidatus caldarchaeum subterraneum 114000.0 1 PMID:29691195 -1.1.99.6 * oryctolagus cuniculus 102000.0 1 PMID:236454 -1.1.99.6 * proteus vulgaris 600000.0 2 PMID:8026480 -1.1.99.6 * sulfurisphaera tokodaii 93000.0 3 PMID:18691525 -1.1.99.6 * thermoproteus tenax 120000.0 2 PMID:30206766 -1.1.99.7 * veillonella parvula 100000.0 3 PMID:4289051;PMID:4333516;PMID:4352258 -1.1.99.9 * arthrobacter sp. 112000.0 2 PMID:3533935 -1.10.3.1 * agaricus bisporus 134000.0 2 PMID:15968468 -1.10.3.1 * alternaria alternata 88000.0 1 * -1.10.3.1 * amphioctopus fangsiao 153800.0 3 PMID:19779653 -1.10.3.1 * asimina triloba 28300.0 2 * -1.10.3.1 * aspergillus oryzae 53000.0 3 PMID:19798497 -1.10.3.1 * beta vulgaris 60000.0 5 PMID:14759157;PMID:15968468;PMID:16436386 -1.10.3.1 * camellia sinensis 250000.0 1 * -1.10.3.1 * castanea henryi 69000.0 1 * -1.10.3.1 * cynara cardunculus var. scolymus 57000.0 1 PMID:15686433 -1.10.3.1 * erimacrus isenbeckii 448000.0 2 PMID:21362494 -1.10.3.1 * eriobotrya japonica 61200.0 1 PMID:16406214 -1.10.3.1 * gossypium hirsutum 55000.0 1 PMID:18795241 -1.10.3.1 * homo sapiens 66700.0 1 PMID:15968468 -1.10.3.1 * ipomoea batatas 205120.0 5 PMID:17651437;PMID:32869889 -1.10.3.1 * lablab purpureus 120000.0 3 PMID:10995279;PMID:16393141 -1.10.3.1 * lactarius salmonicolor 65000.0 1 PMID:18830916 -1.10.3.1 * lonicera japonica 49277.0 2 PMID:23265514 -1.10.3.1 * malus sp. 40000.0 1 * -1.10.3.1 * morus alba 65000.0 1 * -1.10.3.1 * musa x paradisiaca 42000.0 4 PMID:10898614;PMID:11312878;PMID:11812222;PMID:21442554 -1.10.3.1 * mycelia sterilia 240000.0 1 * -1.10.3.1 * neurospora crassa 46000.0 1 PMID:15968468 -1.10.3.1 * nicotiana tabacum 42000.0 2 PMID:10898614;PMID:11812222 -1.10.3.1 * panulirus argus 190000.0 5 PMID:18241679 -1.10.3.1 * pleurotus ostreatus 67000.0 1 PMID:7763931 -1.10.3.1 * portulaca grandiflora 66000.0 5 * -1.10.3.1 * pouteria sapota 18000.0 2 PMID:21087780 -1.10.3.1 * scyllarides latus 440000.0 2 PMID:16010551 -1.10.3.1 * solanum tuberosum 40000.0 1 * -1.10.3.1 * streptomyces glaucescens 30900.0 1 PMID:15968468 -1.10.3.1 * streptomyces griseus 100000.0 3 PMID:12055296 -1.10.3.1 * taraxacum officinale 250000.0 2 PMID:22814940 -1.10.3.1 * trichoderma reesei 61151.0 2 PMID:16939623 -1.10.3.1 * vigna unguiculata 220000.0 3 PMID:18675435 -1.10.3.1 * vitis vinifera 56700.0 4 PMID:20039636;PMID:7948897 -1.10.3.1 * zea mays 158000.0 1 PMID:28040055 -1.10.3.11 * aquifex aeolicus 63900.0 3 PMID:22334648 -1.10.3.11 * arabidopsis thaliana 32000.0 2 PMID:11004460;PMID:12034477 -1.10.3.11 * arum italicum 35000.0 1 PMID:9675036 -1.10.3.11 * gluconobacter oxydans 54000.0 10 PMID:19416958;PMID:23526305 -1.10.3.11 * glycine max 35000.0 1 PMID:9675036 -1.10.3.11 * neurospora crassa 36000.0 1 PMID:10860541 -1.10.3.11 * sauromatum venosum 42000.0 2 PMID:8663588 -1.10.3.11 * scheffersomyces stipitis 36000.0 1 PMID:10860541 -1.10.3.11 * schizosaccharomyces pombe 76000.0 2 PMID:20085745 -1.10.3.11 * trypanosoma brucei brucei 110000.0 3 PMID:20208159;PMID:32565080 -1.10.3.15 * streptomyces griseus 36000.0 1 PMID:16282322 -1.10.3.2 * acer pseudoplatanus 110000.0 2 PMID:26399693;PMID:6847630 -1.10.3.2 * agaricus bisporus 110000.0 1 * -1.10.3.2 * agaricus blazei 66000.0 1 PMID:15647930 -1.10.3.2 * agaricus sinodeliciosus 65000.0 1 PMID:32282952 -1.10.3.2 * agroathelia rolfsii 59000.0 1 * -1.10.3.2 * albifimbria verrucaria 62000.0 1 PMID:14757242 -1.10.3.2 * aquisalibacillus elongatus 75000.0 1 PMID:28161622 -1.10.3.2 * aspergillus nidulans 110000.0 2 PMID:7050088 -1.10.3.2 * bacillus amyloliquefaciens 65000.0 2 PMID:26399693;PMID:30046841;PMID:31759024 -1.10.3.2 * bacillus licheniformis 65000.0 2 PMID:18330561;PMID:34629297 -1.10.3.2 * bacillus pumilus 65000.0 2 PMID:21266052;PMID:26399693;PMID:30046841 -1.10.3.2 * bacillus sp. (in: firmicutes) 180000.0 3 PMID:14568157;PMID:14600793;PMID:20855194 -1.10.3.2 * bacillus sp. msk-01 32000.0 1 PMID:33340630 -1.10.3.2 * bacillus spp. 66000.0 1 PMID:26399693 -1.10.3.2 * bacillus subtilis 58500.0 3 PMID:11884407;PMID:30046841;PMID:32799230 -1.10.3.2 * bacillus vallismortis 70000.0 1 PMID:30046841 -1.10.3.2 * basidiomycete pm1 65000.0 1 PMID:31505206 -1.10.3.2 * bombyx mori 165000.0 4 PMID:19168135;PMID:26399693 -1.10.3.2 * botrytis cinerea 110000.0 5 PMID:26399693 -1.10.3.2 * cantharellus cibarius 92000.0 2 PMID:14672694;PMID:25083593 -1.10.3.2 * carica papaya 260000.0 1 PMID:25192855 -1.10.3.2 * cerrena sp. 58600.0 1 PMID:25356987 -1.10.3.2 * cerrena sp. wr1 64100.0 2 PMID:23081836 -1.10.3.2 * cerrena unicolor 64000.0 3 PMID:15983808;PMID:27793681 -1.10.3.2 * chaetomiaceae 80000.0 2 PMID:12111146 -1.10.3.2 * collybia mongolica 66000.0 1 PMID:20668399 -1.10.3.2 * collybiopsis quercophila 60000.0 1 * -1.10.3.2 * coprinopsis cinerea 60200.0 2 PMID:23073779;PMID:30248451 -1.10.3.2 * coriolisimus fulvocinerea 54000.0 1 PMID:11563958;PMID:25876603 -1.10.3.2 * coriolopsis trogii 54000.0 2 PMID:11563958;PMID:11565899;PMID:12949171;PMID:25876603 -1.10.3.2 * cryptococcus neoformans 75000.0 1 PMID:26399693 -1.10.3.2 * cyathus bulleri 60000.0 2 PMID:15941663;PMID:16261367;PMID:19352024;PMID:25257594 -1.10.3.2 * deconica castanella 64000.0 1 PMID:31271327 -1.10.3.2 * didymosphaeria variabile 84000.0 1 PMID:20933400 -1.10.3.2 * fomes sclerodermeus 67000.0 1 * -1.10.3.2 * fomitopsis pinicola 92000.0 1 PMID:14672694;PMID:25083593 -1.10.3.2 * fomitopsis quercina 71000.0 2 PMID:14504838;PMID:17216440 -1.10.3.2 * funalia rigida 55000.0 1 PMID:11916665 -1.10.3.2 * fusarium solani 72000.0 1 PMID:20716485 -1.10.3.2 * ganoderma fornicatum 54100.0 1 * -1.10.3.2 * ganoderma lucidum 68000.0 1 PMID:11693941 -1.10.3.2 * gelatoporia subvermispora 79000.0 2 PMID:27577103 -1.10.3.2 * geobacillus sp. js12 29800.0 2 PMID:32315700 -1.10.3.2 * geobacter metallireducens 52700.0 1 PMID:29380032 -1.10.3.2 * haloferax volcanii 74000.0 2 PMID:19966030;PMID:22752793 -1.10.3.2 * hericium coralloides 65000.0 1 PMID:22367940 -1.10.3.2 * kitasatospora aureofaciens 75000.0 2 * -1.10.3.2 * lactifluus piperatus 67000.0 1 PMID:4863037 -1.10.3.2 * lentinula edodes 74000.0 5 PMID:11565899;PMID:12949171;PMID:26399693 -1.10.3.2 * lentinus brumalis 63400.0 1 PMID:20943172 -1.10.3.2 * lentinus sajor-caju 61000.0 1 PMID:16568314 -1.10.3.2 * lentinus tigrinus 69100.0 2 PMID:17013550 -1.10.3.2 * leucaena leucocephala 220000.0 1 * -1.10.3.2 * limnospira platensis 66000.0 1 PMID:28384218 -1.10.3.2 * loweporus lividus 65000.0 2 PMID:18607547 -1.10.3.2 * loweporus lividus mtcc-1178 64800.0 1 * -1.10.3.2 * macrocybe gigantea 63000.0 1 PMID:14766229 -1.10.3.2 * manduca sexta 90000.0 2 PMID:19576986 -1.10.3.2 * melanocarpus albomyces 100000.0 3 PMID:12111146;PMID:19780817 -1.10.3.2 * mycothermus thermophilus 82000.0 1 * -1.10.3.2 * myrioconium sp. 72700.0 1 PMID:17955194 -1.10.3.2 * nephotettix cincticeps 85000.0 1 PMID:26399693 -1.10.3.2 * neurospora crassa 65000.0 3 PMID:207349;PMID:4278681 -1.10.3.2 * panus rudis 58000.0 2 * -1.10.3.2 * peltigera aphthosa 165000.0 2 PMID:17681009 -1.10.3.2 * peniophora sp. 63000.0 1 * -1.10.3.2 * perenniporia fraxinea 47600.0 2 PMID:18467859 -1.10.3.2 * pestalotiopsis sp. kf079 63000.0 2 PMID:30991752 -1.10.3.2 * phellinus ribis 76000.0 2 PMID:11488603 -1.10.3.2 * phlebia fascicularia 60000.0 1 PMID:15195712 -1.10.3.2 * phlebia radiata 60000.0 1 PMID:15941663;PMID:19352024;PMID:25257594 -1.10.3.2 * phoma sp. 151200.0 1 PMID:19455326 -1.10.3.2 * pleurotus cornucopiae 66000.0 1 PMID:19807674 -1.10.3.2 * pleurotus eryngii 68000.0 2 PMID:16075291;PMID:17216440 -1.10.3.2 * pleurotus floridanus 82000.0 4 PMID:11347272;PMID:11688212 -1.10.3.2 * pleurotus ostreatus 71000.0 11 PMID:11565899;PMID:15647930;PMID:18692377;PMID:19916914;PMID:207349;PMID:22806800 -1.10.3.2 * pleurotus pulmonarius 46000.0 2 PMID:12872309 -1.10.3.2 * podospora anserina 390000.0 3 PMID:4990197 -1.10.3.2 * polypus dispansus 62000.0 1 PMID:11563958;PMID:15178417 -1.10.3.2 * populus x canadensis 110000.0 2 PMID:9914531 -1.10.3.2 * prunus persica 73500.0 1 * -1.10.3.2 * pseudomonas putida 59000.0 1 * -1.10.3.2 * pseudomonas syringae 72000.0 1 PMID:26399693 -1.10.3.2 * pyricularia grisea 70000.0 1 PMID:14568157;PMID:14600793 -1.10.3.2 * pyrrhoderma noxium 70000.0 1 * -1.10.3.2 * rhizoctonia solani 130000.0 2 PMID:8598061 -1.10.3.2 * rigidoporus microporus 59000.0 1 * -1.10.3.2 * sarcomyxa serotina 57000.0 1 PMID:11563958;PMID:12664149;PMID:26495441 -1.10.3.2 * schinus molle 110000.0 2 PMID:6847630 -1.10.3.2 * shiraia sp. super-h168 70780.0 2 * -1.10.3.2 * sinorhizobium meliloti 45000.0 1 * -1.10.3.2 * solorina crocea 175000.0 2 PMID:17681009 -1.10.3.2 * sphingobacterium sp. ksn-11 90000.0 1 PMID:26399693;PMID:32601857 -1.10.3.2 * steccherinum ochraceum 63000.0 3 PMID:19120652 -1.10.3.2 * streptomyces cyaneus 75000.0 2 PMID:26399693;PMID:30046841 -1.10.3.2 * streptomyces griseus 114000.0 2 PMID:12801920;PMID:26399693 -1.10.3.2 * streptomyces viridochromogenes 90000.0 1 PMID:25778839 -1.10.3.2 * thermochaetoides thermophila 110000.0 4 PMID:7050088;PMID:9726856 -1.10.3.2 * thermothelomyces thermophilus 85000.0 1 PMID:26399693 -1.10.3.2 * thermus thermophilus 53000.0 3 PMID:15999224;PMID:29063287 -1.10.3.2 * thielavia sp. 70000.0 1 PMID:30268749 -1.10.3.2 * toxicodendron succedaneum 130000.0 1 PMID:26399693 -1.10.3.2 * toxicodendron vernicifluum 120000.0 5 PMID:26399693;PMID:4985785 -1.10.3.2 * trametes cinnabarina 70000.0 1 PMID:14568157;PMID:14600793 -1.10.3.2 * trametes hirsuta 269000.0 8 PMID:11563958;PMID:16791729;PMID:19221878;PMID:20056172 -1.10.3.2 * trametes maxima 57000.0 1 PMID:11563958;PMID:12664149;PMID:26495441 -1.10.3.2 * trametes ochracea 63000.0 2 PMID:11563958;PMID:12018276;PMID:15178417 -1.10.3.2 * trametes polyzona 71000.0 4 PMID:23775771;PMID:33299811;PMID:34232363 -1.10.3.2 * trametes pubescens 68000.0 2 PMID:12101303;PMID:17381747;PMID:23196221 -1.10.3.2 * trametes sanguinea 74000.0 6 PMID:14504838;PMID:16075291;PMID:17186237;PMID:17216440 -1.10.3.2 * trametes sp. 74000.0 7 PMID:11563958;PMID:12664149;PMID:21148825;PMID:23712478;PMID:26495441 -1.10.3.2 * trametes versicolor 110000.0 7 PMID:15769520;PMID:15941663;PMID:16410773;PMID:18688574;PMID:19352024;PMID:25257594;PMID:7050088 -1.10.3.2 * trametes villosa 63000.0 1 PMID:16828870 -1.10.3.2 * trichoderma harzianum 79000.0 1 * -1.10.3.2 * trichophyton rubrum 65000.0 1 PMID:18330561 -1.10.3.2 * truncospora tephropora 65000.0 2 PMID:12101303;PMID:17381747 -1.10.3.2 * uncultured bacterium 68000.0 1 PMID:34054745 -1.10.3.2 * volvariella volvacea 58000.0 1 PMID:14717699 -1.10.3.3 * acremonium 80000.0 1 PMID:7961590 -1.10.3.3 * citrus unshiu 141000.0 3 * -1.10.3.3 * cucumis sativus 140000.0 6 PMID:2143984;PMID:4303504 -1.10.3.3 * cucurbita maxima 150000.0 1 * -1.10.3.3 * cucurbita moschata 61000.0 1 PMID:32626358 -1.10.3.3 * cucurbita pepo 145000.0 2 PMID:1548698;PMID:32626358 -1.10.3.3 * cucurbita pepo condensa 35000.0 5 * -1.10.3.3 * cucurbita pepo medullosa 140000.0 5 PMID:4200863;PMID:440113;PMID:4810061 -1.10.3.3 * cucurbita sp. 64000.0 2 PMID:2143984 -1.10.3.3 * triticum aestivum 140000.0 3 * -1.10.3.4 * streptomyces griseus 23000.0 1 PMID:16282322 -1.10.5.1 * bos taurus 40000.0 1 PMID:9050836 -1.10.5.1 * homo sapiens 50000.0 3 PMID:9050836;PMID:9367528 -1.11.1.1 * clostridium acetobutylicum 80000.0 3 PMID:19118342 -1.11.1.1 * clostridium perfringens 22000.0 1 PMID:10049706 -1.11.1.1 * enterococcus faecalis 201400.0 7 PMID:13416259;PMID:199166;PMID:2501303;PMID:7766608;PMID:8428993 -1.11.1.1 * nitratidesulfovibrio vulgaris 22000.0 1 PMID:10049706 -1.11.1.1 * pseudomonas fluorescens 100000.0 4 PMID:16159773 -1.11.1.10 * leptoxyphium fumago 46000.0 5 PMID:18407660;PMID:19823777;PMID:3774552;PMID:566840;PMID:5949836 -1.11.1.10 * musa x paradisiaca 43000.0 1 * -1.11.1.10 * streptomyces toyocaensis 109000.0 2 PMID:8605030 -1.11.1.11 * alnus rubra 47000.0 1 * -1.11.1.11 * arabidopsis thaliana 440000.0 3 PMID:19859717;PMID:34194454 -1.11.1.11 * arachis hypogaea 47000.0 1 * -1.11.1.11 * brassica rapa 28000.0 1 PMID:20619666 -1.11.1.11 * cenchrus americanus 27500.0 2 PMID:19450902 -1.11.1.11 * chlamydomonas sp. 31000.0 2 PMID:10729193 -1.11.1.11 * chlorella vulgaris 32000.0 1 PMID:9672748 -1.11.1.11 * citrus x limon 29000.0 2 * -1.11.1.11 * cyanidioschyzon merolae 30000.0 1 PMID:19859717 -1.11.1.11 * eleusine coracana 28500.0 1 PMID:23065288 -1.11.1.11 * euglena gracilis 76000.0 4 PMID:20015051;PMID:6772104 -1.11.1.11 * galdieria partita 28000.0 1 PMID:11333315 -1.11.1.11 * glycine max 48000.0 8 PMID:16665340;PMID:8638916;PMID:9443387 -1.11.1.11 * gossypium hirsutum 64200.0 3 PMID:17635221 -1.11.1.11 * helicoverpa zea 10000.0 1 * -1.11.1.11 * lathyrus oleraceus 57000.0 2 PMID:23196087 -1.11.1.11 * leishmania major 30000.0 1 PMID:18822369 -1.11.1.11 * lupinus albus 47000.0 1 * -1.11.1.11 * medicago sativa 47000.0 1 * -1.11.1.11 * musa x paradisiaca 208900.0 1 PMID:30408454 -1.11.1.11 * oryza sativa 34000.0 2 * -1.11.1.11 * pallavicinia lyellii 28000.0 1 PMID:20619666 -1.11.1.11 * panicum virgatum 29500.0 2 PMID:23809633 -1.11.1.11 * populus tomentosa 74000.0 3 PMID:17899442 -1.11.1.11 * raphanus sativus 28000.0 1 * -1.11.1.11 * ricinus communis 34000.0 1 PMID:15639224 -1.11.1.11 * solanum tuberosum 31000.0 1 * -1.11.1.11 * spinacia oleracea 30000.0 1 * -1.11.1.11 * trifolium subterraneum 47000.0 1 * -1.11.1.11 * vicia faba 47000.0 1 * -1.11.1.11 * vicia sativa 47000.0 1 * -1.11.1.11 * vigna unguiculata 47000.0 1 * -1.11.1.11 * zea mays 28000.0 1 PMID:20619666 -1.11.1.12 * bombus ignitus 19000.0 1 PMID:19808099 -1.11.1.12 * bos taurus 20000.0 2 PMID:19433132;PMID:2233312;PMID:8436014 -1.11.1.12 * canis lupus familiaris 20000.0 1 PMID:19433132;PMID:2233312 -1.11.1.12 * homo sapiens 69000.0 7 PMID:17020817;PMID:18215741;PMID:24170573;PMID:7851631;PMID:9915822 -1.11.1.12 * hydra vulgaris 21480.0 1 PMID:16919897 -1.11.1.12 * momordica charantia 22500.0 1 PMID:19538123 -1.11.1.12 * mus musculus 20000.0 1 PMID:19433132;PMID:2233312 -1.11.1.12 * oryza sativa 21000.0 1 PMID:17562293 -1.11.1.12 * raphanus sativus 21500.0 2 PMID:16944266 -1.11.1.12 * rattus norvegicus 34000.0 7 PMID:11903656;PMID:15670826;PMID:16181973;PMID:18723092;PMID:7524677 -1.11.1.12 * schistosoma mansoni 20000.0 2 PMID:19714775;PMID:7066358;PMID:8706688 -1.11.1.12 * sus scrofa 23000.0 3 PMID:3978121;PMID:7066358;PMID:8706688 -1.11.1.12 * taiwanofungus camphoratus 18000.0 1 * -1.11.1.13 * abortiporus biennis 45000.0 1 * -1.11.1.13 * agaricus bisporus 40000.0 1 PMID:11330710 -1.11.1.13 * agrocybe praecox 42000.0 2 PMID:14767623 -1.11.1.13 * bacillus velezensis 46000.0 1 PMID:33131742 -1.11.1.13 * bjerkandera adusta 44000.0 4 PMID:10887291;PMID:12070683;PMID:22435143;PMID:8647081;PMID:8899997;PMID:9165096 -1.11.1.13 * bjerkandera sp. 45000.0 4 PMID:10682282 -1.11.1.13 * clitocybula dusenii 43000.0 1 * -1.11.1.13 * coriolopsis trogii 45000.0 1 * -1.11.1.13 * deuteromycotina sp. 43000.0 1 PMID:10887291;PMID:12070683;PMID:22435143;PMID:8647081;PMID:8899997;PMID:9165096 -1.11.1.13 * dichomitus squalens 50000.0 4 PMID:19381471;PMID:8917615 -1.11.1.13 * gelatoporia subvermispora 62500.0 1 * -1.11.1.13 * gymnopus dryophilus 43000.0 1 * -1.11.1.13 * hypholoma frowardii 50000.0 1 * -1.11.1.13 * irpex flavus 99000.0 1 * -1.11.1.13 * lentinula edodes 660000.0 7 PMID:11425471;PMID:1366641 -1.11.1.13 * lentinus tigrinus 50500.0 3 PMID:19578878 -1.11.1.13 * lenzites betulinus 40000.0 1 PMID:12387901 -1.11.1.13 * musa x paradisiaca 43000.0 1 PMID:10887291;PMID:12070683;PMID:22435143;PMID:8647081;PMID:8899997;PMID:9165096 -1.11.1.13 * panaeolus sphinctrinus 42000.0 1 * -1.11.1.13 * phanerochaete sordida 45000.0 1 PMID:8135519 -1.11.1.13 * phanerodontia chrysosporium 46000.0 6 PMID:10682282;PMID:14524699;PMID:19027802 -1.11.1.13 * phlebia radiata 50000.0 2 PMID:2337352 -1.11.1.13 * phlebiopsis flavidoalba 45000.0 1 * -1.11.1.13 * pleurotus eryngii 43000.0 1 PMID:10887291;PMID:12070683;PMID:22435143;PMID:8647081;PMID:8899997;PMID:9165096 -1.11.1.13 * pleurotus ostreatus 47000.0 6 PMID:10729203;PMID:10887291;PMID:12070683;PMID:14767623;PMID:22435143;PMID:8647081;PMID:8899997;PMID:9165096 -1.11.1.13 * rigidoporus microporus 42000.0 1 * -1.11.1.13 * schizophyllum commune 40000.0 1 PMID:12387901 -1.11.1.13 * schizophyllum sp. 48700.0 1 * -1.11.1.13 * stropharia coronilla 43000.0 3 * -1.11.1.13 * stropharia rugosoannulata 43000.0 1 * -1.11.1.13 * trametes gibbosa 43000.0 1 * -1.11.1.13 * trametes hirsuta 45000.0 1 * -1.11.1.13 * trametes versicolor 49000.0 6 PMID:8424685;PMID:8424691 -1.11.1.13 * trichophyton rubrum 42000.0 1 PMID:14767623 -1.11.1.14 * acinetobacter calcoaceticus 130000.0 1 PMID:18506630 -1.11.1.14 * bjerkandera sp. 43000.0 1 PMID:23330392;PMID:9624124 -1.11.1.14 * brevibacillus laterosporus 205000.0 1 * -1.11.1.14 * gloeophyllum sepiarium 42000.0 1 PMID:19916925 -1.11.1.14 * lentinus sajor-caju 40000.0 1 * -1.11.1.14 * lenzites betulinus 43000.0 1 PMID:23330392;PMID:9624124 -1.11.1.14 * loweporus lividus 40000.0 1 * -1.11.1.14 * phanerodontia chrysosporium 43000.0 6 PMID:16593451;PMID:2987213;PMID:4026322;PMID:6497376 -1.11.1.14 * streptomyces viridosporus 17910.0 1 * -1.11.1.14 * trametes sanguinea 40000.0 1 * -1.11.1.14 * trametes versicolor 30000.0 1 PMID:22862820 -1.11.1.16 * bjerkandera adusta 36400.0 1 PMID:18707878 -1.11.1.16 * bjerkandera sp. 47000.0 1 * -1.11.1.16 * pleurotus eryngii 45000.0 7 PMID:10187820;PMID:10508113;PMID:21980920;PMID:8647081 -1.11.1.16 * pseudomonas putida 120000.0 2 PMID:23820555 -1.11.1.16 * stereum ostrea 40000.0 1 PMID:23124346 -1.11.1.17 * marichromatium gracile 27500.0 2 PMID:11399772 -1.11.1.18 * ascophyllum nodosum 136000.0 4 PMID:2400770 -1.11.1.18 * corallina officinalis 740000.0 3 PMID:1426568;PMID:21046195 -1.11.1.18 * delisea pulchra 65458.0 1 PMID:22006105 -1.11.1.18 * ecklonia cava subsp. stolonifera 83000.0 1 PMID:9861726 -1.11.1.18 * fucus distichus 65000.0 1 PMID:2261454 -1.11.1.18 * gracilaria firma 84000.0 1 PMID:23684235 -1.11.1.18 * kitasatospora aureofaciens 90000.0 7 PMID:1783900;PMID:19883129;PMID:3122838 -1.11.1.18 * macrocystis pyrifera 74000.0 1 PMID:2261454 -1.11.1.18 * streptomyces griseus 90000.0 5 PMID:3151989 -1.11.1.18 * streptomyces venezuelae 136000.0 3 PMID:2628543;PMID:8868441 -1.11.1.19 * anabaena sp. 209000.0 4 PMID:19801472 -1.11.1.19 * auricularia auricula-judae 60000.0 3 PMID:19756587;PMID:20495915 -1.11.1.19 * bacillus subtilis 48000.0 1 PMID:23820555 -1.11.1.19 * geotrichum candidum 60000.0 4 PMID:10049859;PMID:10742277 -1.11.1.19 * pleurotus ostreatus 57260.0 1 PMID:19099183 -1.11.1.19 * pleurotus sapidus 115000.0 1 PMID:28831735 -1.11.1.19 * pseudomonas aeruginosa 64000.0 2 PMID:22161141 -1.11.1.19 * pseudomonas putida 120000.0 1 PMID:23820555 -1.11.1.19 * streptomyces avermitilis 55000.0 1 PMID:28089379 -1.11.1.19 * thanatephorus cucumeris 60000.0 12 PMID:14684913;PMID:15313183;PMID:16511141;PMID:17928290;PMID:19099183;PMID:19217546 -1.11.1.19 * thermobifida fusca yx 46000.0 2 PMID:19967355 -1.11.1.19 * vibrio cholerae 70000.0 1 PMID:26431465 -1.11.1.19 * zymomonas mobilis 108000.0 2 PMID:24063237 -1.11.1.20 * mus musculus 21670.0 2 PMID:18006499 -1.11.1.20 * sus scrofa 20000.0 1 PMID:18006499 -1.11.1.21 * archaeoglobus fulgidus 169000.0 4 PMID:10543446;PMID:11699646;PMID:18178143 -1.11.1.21 * bacillus pumilus 62400.0 3 PMID:21996477 -1.11.1.21 * bradyrhizobium japonicum 136000.0 2 PMID:1645695 -1.11.1.21 * burkholderia cenocepacia 97000.0 3 PMID:17371508 -1.11.1.21 * burkholderia pseudomallei 81600.0 2 PMID:12454496;PMID:18178143 -1.11.1.21 * escherichia coli 165000.0 3 PMID:18178143;PMID:3886630 -1.11.1.21 * geobacillus stearothermophilus 80000.0 1 PMID:18178143 -1.11.1.21 * haloarcula marismortui 94000.0 4 PMID:7947969;PMID:9924978 -1.11.1.21 * halobacterium salinarum 240000.0 2 PMID:8320233 -1.11.1.21 * klebsiella pneumoniae 250000.0 2 PMID:2029529 -1.11.1.21 * mycobacterium sp. 160000.0 2 PMID:14553939;PMID:9395452 -1.11.1.21 * mycobacterium tuberculosis 175000.0 9 PMID:10933818;PMID:14553939;PMID:18178143;PMID:30140323;PMID:33444527;PMID:9006925;PMID:9395452;PMID:9766000 -1.11.1.21 * mycolicibacterium smegmatis 330000.0 3 PMID:7673210 -1.11.1.21 * neurospora crassa 177000.0 1 PMID:29305053 -1.11.1.21 * oceanobacillus oncorhynchi subsp. incaldanensis 280000.0 2 * -1.11.1.21 * penicillium simplicissimum 170000.0 2 PMID:10543446;PMID:8631329 -1.11.1.21 * pyricularia grisea 352000.0 12 PMID:19000033;PMID:22822072 -1.11.1.21 * rhodobacter capsulatus 236000.0 2 PMID:18178143;PMID:3571290 -1.11.1.21 * synechococcus elongatus pcc 7942 = fachb-805 80500.0 1 PMID:9207193 -1.11.1.21 * synechocystis sp. 170000.0 5 PMID:10543446;PMID:11699646;PMID:18178143;PMID:8631329 -1.11.1.22 * synechocystis sp. 18451.0 4 PMID:11418106 -1.11.1.23 * pseudomonas syringae 73000.0 5 PMID:10664856;PMID:18656958 -1.11.1.23 * streptomyces wedmorensis 89000.0 5 PMID:11457256;PMID:14529267;PMID:16511089;PMID:7500951 -1.11.1.24 * aquifex aeolicus 480000.0 1 PMID:30251668 -1.11.1.24 * arenicola marina 50000.0 3 PMID:18503776 -1.11.1.24 * ascaris suum 21589.0 1 PMID:10704594 -1.11.1.24 * azumapecten farreri 20100.0 2 PMID:18704754 -1.11.1.24 * babesia microti 22300.0 1 PMID:32133382 -1.11.1.24 * baylisascaris schroederi 21600.0 1 PMID:29068407 -1.11.1.24 * bombus ignitus 27000.0 2 PMID:19932185 -1.11.1.24 * branchiostoma belcheri tsingtauense 24000.0 2 PMID:28384204 -1.11.1.24 * brassica napus 260000.0 2 PMID:18279387 -1.11.1.24 * caenorhabditis elegans 20000.0 2 PMID:19064914 -1.11.1.24 * haliotis discus discus 70500.0 3 PMID:18226547;PMID:19460442 -1.11.1.24 * homo sapiens 219700.0 8 PMID:10751410;PMID:17329258;PMID:17519234;PMID:18052930 -1.11.1.24 * lathyrus oleraceus 388000.0 7 PMID:15333640;PMID:17881238 -1.11.1.24 * leishmania infantum 27345.0 1 PMID:12446214 -1.11.1.24 * mus musculus 20000.0 1 PMID:19208552 -1.11.1.24 * mycobacterium tuberculosis 19320.0 1 PMID:19737009 -1.11.1.24 * opisthorchis viverrini 50000.0 3 PMID:18538872 -1.11.1.24 * penaeus japonicus 28000.0 2 PMID:24056278 -1.11.1.24 * plasmodium falciparum 400000.0 3 PMID:11295184;PMID:12946843 -1.11.1.24 * plasmodium vivax 47460.0 2 PMID:22429898 -1.11.1.24 * plasmodium yoelii 47070.0 2 PMID:22429898 -1.11.1.24 * psoroptes ovis 23400.0 2 PMID:19195412 -1.11.1.24 * pyrococcus horikoshii 25000.0 1 PMID:15625325 -1.11.1.24 * rattus norvegicus 230000.0 4 PMID:17974571 -1.11.1.24 * rhizobium etli 20080.0 1 PMID:15686565 -1.11.1.24 * saccharolobus solfataricus 18530.0 8 PMID:18355320;PMID:19338062 -1.11.1.24 * sedum lineare 17000.0 2 PMID:10998352 -1.11.1.24 * sus scrofa 20000.0 1 PMID:19208552 -1.11.1.24 * taenia solium 22000.0 1 PMID:16995398 -1.11.1.24 * taiwanofungus camphoratus 25081.0 5 PMID:17031636;PMID:17103164 -1.11.1.24 * thunnus maccoyii 400000.0 3 PMID:20211754 -1.11.1.24 * toxoplasma gondii 250000.0 6 PMID:15507457 -1.11.1.24 * trichomonas vaginalis 18000.0 1 PMID:15904985 -1.11.1.24 * vibrio vulnificus 22168.0 1 PMID:23095744 -1.11.1.24 * xylella fastidiosa 17813.0 1 PMID:20335172 -1.11.1.25 * thermotoga maritima 386000.0 4 PMID:22866991 -1.11.1.26 * campylobacter jejuni 48000.0 1 PMID:31516338 -1.11.1.26 * escherichia coli 195000.0 2 PMID:30237544 -1.11.1.26 * pseudomonas aeruginosa 660000.0 3 PMID:31909437 -1.11.1.26 * thermus aquaticus 235000.0 2 PMID:10862622 -1.11.1.27 * haemophilus influenzae 53216.0 2 PMID:12606554 -1.11.1.27 * homo sapiens 52000.0 5 PMID:12495419;PMID:20919932;PMID:33060708 -1.11.1.27 * rattus norvegicus 337600.0 2 PMID:30717364 -1.11.1.27 * saccharomyces cerevisiae 60000.0 1 PMID:19332553 -1.11.1.28 * escherichia coli 195000.0 2 PMID:30237544 -1.11.1.3 * lathyrus oleraceus 70000.0 2 PMID:10938370 -1.11.1.5 * acidithiobacillus thiooxidans 32000.0 1 * -1.11.1.5 * campylobacter jejuni 37000.0 2 PMID:18086814 -1.11.1.5 * escherichia coli 70000.0 1 PMID:12589560 -1.11.1.5 * marinobacter nauticus 57500.0 4 PMID:10525144 -1.11.1.5 * methylococcus capsulatus 80000.0 3 PMID:16336269;PMID:9325424 -1.11.1.5 * nitrosomonas europaea 90000.0 2 PMID:8163487 -1.11.1.5 * paracoccus denitrificans 108000.0 15 PMID:12590592;PMID:2173903;PMID:9201942 -1.11.1.5 * paracoccus pantotrophus 75000.0 2 PMID:17361419 -1.11.1.5 * pseudomonas aeruginosa 44000.0 4 PMID:17568678;PMID:4356445;PMID:8543038 -1.11.1.5 * pseudomonas denitrificans (nom. rej.) 63000.0 1 PMID:226080 -1.11.1.5 * saccharomyces cerevisiae 35240.0 6 PMID:19249872;PMID:23517193;PMID:6082750;PMID:6257175;PMID:6257176 -1.11.1.5 * stutzerimonas stutzeri 87000.0 5 PMID:12459896;PMID:2173903 -1.11.1.6 * acinetobacter sp. ys0810 229000.0 1 PMID:25045672 -1.11.1.6 * aspergillus nidulans 360000.0 2 PMID:10858500 -1.11.1.6 * aspergillus niger 385000.0 2 PMID:7153210 -1.11.1.6 * bacillus anthracis 58000.0 1 PMID:21723851 -1.11.1.6 * bacillus sp. (in: firmicutes) 230000.0 4 PMID:10661897;PMID:10714995;PMID:15158713;PMID:18923550;PMID:21077118 -1.11.1.6 * bacillus subtilis 240000.0 2 PMID:17876537;PMID:21524057;PMID:32178 -1.11.1.6 * beta vulgaris subsp. cicla 235000.0 2 PMID:11342285 -1.11.1.6 * bifidobacterium asteroides 110000.0 2 PMID:23154971 -1.11.1.6 * bos taurus 60000.0 1 PMID:17876537;PMID:21524057;PMID:32178 -1.11.1.6 * brassica oleracea 308000.0 3 * -1.11.1.6 * burkholderia cenocepacia 97000.0 2 PMID:17371508 -1.11.1.6 * candida tropicalis 210000.0 2 PMID:10382262;PMID:3464;PMID:7117250 -1.11.1.6 * canis lupus familiaris 230000.0 2 PMID:10661897;PMID:10714995;PMID:18923550;PMID:21077118 -1.11.1.6 * capra capra 339000.0 3 PMID:17876537;PMID:21524057;PMID:32178;PMID:8302290 -1.11.1.6 * cereibacter sphaeroides 150000.0 3 PMID:9575236 -1.11.1.6 * colwellia sp. 145000.0 1 PMID:18557912 -1.11.1.6 * cucurbita sp. 230000.0 2 PMID:16663408 -1.11.1.6 * cytobacillus firmus 84000.0 3 PMID:7748885 -1.11.1.6 * enterococcus faecalis 54000.0 1 PMID:12399505 -1.11.1.6 * eriocheir sinensis 58860.0 1 PMID:23171400 -1.11.1.6 * escherichia coli 337000.0 2 PMID:374409 -1.11.1.6 * frankia sp. r43 83200.0 1 * -1.11.1.6 * gluconobacter oxydans 320000.0 2 PMID:18203610;PMID:18369615;PMID:21317031;PMID:23545640 -1.11.1.6 * haliotis discus discus 56000.0 1 PMID:18187341 -1.11.1.6 * halobacterium salinarum 240000.0 3 PMID:28892106;PMID:3956497;PMID:7814327;PMID:8320233 -1.11.1.6 * homo sapiens 60000.0 1 PMID:17408968 -1.11.1.6 * hydra vulgaris 57440.0 1 PMID:22521743 -1.11.1.6 * klebsiella pneumoniae 200000.0 2 PMID:15132174 -1.11.1.6 * kloeckera sp. 240000.0 2 PMID:28892106;PMID:3956497;PMID:7814327;PMID:8320233 -1.11.1.6 * komagataella pastoris 223000.0 1 PMID:11421814 -1.11.1.6 * lathyrus oleraceus 57000.0 1 PMID:10694065 -1.11.1.6 * lens culinaris 225000.0 2 PMID:10382262;PMID:3464;PMID:7117250 -1.11.1.6 * medicago sativa 59000.0 3 PMID:17583521 -1.11.1.6 * mesembryanthemum crystallinum 320000.0 3 PMID:18203610;PMID:21317031;PMID:23545640 -1.11.1.6 * metallosphaera hakonensis 33000.0 1 PMID:17983766 -1.11.1.6 * methanobrevibacter arboriphilus 260000.0 2 PMID:11425719 -1.11.1.6 * methanosarcina barkeri 190000.0 2 PMID:10382262;PMID:3464;PMID:7117250 -1.11.1.6 * mycobacterium sp. 160000.0 2 PMID:14553939 -1.11.1.6 * mycothermus thermophilus 320000.0 2 PMID:18369615;PMID:21317031 -1.11.1.6 * neurospora crassa 320000.0 4 PMID:12033445;PMID:37891 -1.11.1.6 * oceanobacillus oncorhynchi 280000.0 2 * -1.11.1.6 * oryza sativa 234000.0 3 PMID:17934694;PMID:21978604 -1.11.1.6 * paracoccidioides brasiliensis 244000.0 4 PMID:14755642;PMID:18799136;PMID:19897569 -1.11.1.6 * penicillium simplicissimum 170000.0 2 PMID:8631329 -1.11.1.6 * petroselinum crispum 183000.0 1 PMID:17516252 -1.11.1.6 * phaseolus vulgaris 59000.0 3 PMID:17583521 -1.11.1.6 * phytophthora nicotianae 58400.0 3 PMID:18705863 -1.11.1.6 * pibocella sp. 170000.0 1 PMID:18557912 -1.11.1.6 * portunus trituberculatus 58500.0 1 PMID:23073768 -1.11.1.6 * protaetia brevitarsis 56000.0 1 PMID:17919956 -1.11.1.6 * pseudomonas aeruginosa 228000.0 2 PMID:7592431 -1.11.1.6 * psychrobacter piscatorii 247000.0 2 PMID:22408420;PMID:3571290 -1.11.1.6 * pyrobaculum calidifontis 154000.0 3 PMID:12029047 -1.11.1.6 * rhodobacter capsulatus 236000.0 2 PMID:22408420;PMID:3571290 -1.11.1.6 * rhodospirillum rubrum 318000.0 5 PMID:16728955;PMID:18062223 -1.11.1.6 * ruegeria pomeroyi dss-3 54000.0 2 PMID:17395199 -1.11.1.6 * scedosporium boydii 460000.0 1 PMID:25355796 -1.11.1.6 * serratia marcescens 230000.0 2 PMID:10661897;PMID:10714995;PMID:18923550;PMID:21077118 -1.11.1.6 * sulfitobacter sp. 185000.0 1 PMID:18557912 -1.11.1.6 * thermoascus aurantiacus 330000.0 1 * -1.11.1.6 * thermus brockianus 178000.0 2 PMID:12892493 -1.11.1.6 * trigonopsis variabilis 227300.0 2 * -1.11.1.6 * vibrio rumoiensis 230000.0 2 PMID:10661897;PMID:10714995;PMID:18923550;PMID:21077118 -1.11.1.6 * vibrio vulnificus 240000.0 1 PMID:28892106;PMID:3956497;PMID:7814327;PMID:8320233 -1.11.1.6 * zavarzinia compransoris 150000.0 2 * -1.11.1.6 * zea mays 60000.0 1 * -1.11.1.7 * acorus calamus 32000.0 1 PMID:17056613 -1.11.1.7 * aedes aegypti 63000.0 1 PMID:10871050 -1.11.1.7 * agaricales sp. 'arthromyces ramosus' 41000.0 1 * -1.11.1.7 * aggregatibacter actinomycetemcomitans 53600.0 1 PMID:18616592 -1.11.1.7 * allium sativum 36500.0 1 PMID:16377850 -1.11.1.7 * anabaena sp. 54000.0 3 PMID:10561543;PMID:19801472 -1.11.1.7 * arachis hypogaea 42000.0 2 PMID:16663767 -1.11.1.7 * armoracia rusticana 60000.0 4 PMID:16008083;PMID:18274791;PMID:20681636;PMID:22339595;PMID:23026679 -1.11.1.7 * armoracia sp. 44000.0 6 PMID:11068874;PMID:15461141;PMID:7130156 -1.11.1.7 * artocarpus heterophyllus 104000.0 1 PMID:29626603 -1.11.1.7 * beta vulgaris 45000.0 1 PMID:20405843 -1.11.1.7 * bos taurus 90000.0 4 PMID:19214766;PMID:20187078;PMID:6417136 -1.11.1.7 * brassica napus 39300.0 2 PMID:11834124;PMID:11934076 -1.11.1.7 * brassica oleracea 48000.0 2 PMID:15826079 -1.11.1.7 * brassica oleracea var. capitata 44000.0 2 * -1.11.1.7 * brassica rapa 45000.0 1 PMID:20405843 -1.11.1.7 * calotropis procera 46500.0 1 * -1.11.1.7 * camellia sinensis 34660.0 2 PMID:9276947 -1.11.1.7 * catharanthus roseus 33750.0 1 PMID:18065566 -1.11.1.7 * chromolaena odorata 43000.0 1 PMID:16632882 -1.11.1.7 * citrus jambhiri 56000.0 1 PMID:18633734 -1.11.1.7 * commiphora gileadensis 40000.0 1 PMID:31004641 -1.11.1.7 * cynara cardunculus 51000.0 1 * -1.11.1.7 * cytisus multiflorus 51000.0 1 PMID:25246165 -1.11.1.7 * elaeis guineensis 57000.0 1 PMID:12027897 -1.11.1.7 * elais guineensis 200000.0 2 * -1.11.1.7 * elizabethkingia meningoseptica 220000.0 2 PMID:10561543;PMID:19801472 -1.11.1.7 * escherichia coli 39855.0 5 PMID:12514184;PMID:22187429 -1.11.1.7 * fagopyrum esculentum 58100.0 2 PMID:16403545 -1.11.1.7 * ficus carica 30000.0 1 * -1.11.1.7 * gossypium hirsutum 64000.0 4 PMID:18649146 -1.11.1.7 * helianthus annuus 47000.0 1 PMID:18586509 -1.11.1.7 * homo sapiens 165000.0 3 PMID:18929642;PMID:9388242 -1.11.1.7 * ipomoea batatas 42030.0 3 PMID:17936696 -1.11.1.7 * ipomoea carnea 45000.0 2 PMID:18788710 -1.11.1.7 * lepidium sativum 40000.0 2 PMID:33140461 -1.11.1.7 * leptogium saturninum 81000.0 3 PMID:22056522 -1.11.1.7 * lichtheimia corymbifera 40160.0 2 * -1.11.1.7 * momordica charantia 43000.0 1 PMID:18473951 -1.11.1.7 * mycobacterium avium 33000.0 1 PMID:19827095 -1.11.1.7 * neisseria gonorrhoeae 68000.0 2 PMID:28388513 -1.11.1.7 * neurospora crassa 133000.0 3 * -1.11.1.7 * nicotiana tabacum 54000.0 4 * -1.11.1.7 * oryza sativa 27000.0 1 PMID:19833360 -1.11.1.7 * ovis aries 82000.0 2 * -1.11.1.7 * pelargonium graveolens 44000.0 2 PMID:11068874;PMID:15461141 -1.11.1.7 * persea americana 40000.0 1 * -1.11.1.7 * plasmodium falciparum 30000.0 3 PMID:15802233 -1.11.1.7 * pleurotus ostreatus 73000.0 2 PMID:16535590 -1.11.1.7 * pyrococcus furiosus 36000.0 3 PMID:15547260 -1.11.1.7 * raphanus sativus 66000.0 2 PMID:16008083;PMID:22339595 -1.11.1.7 * rattus norvegicus 45000.0 2 PMID:7138501 -1.11.1.7 * roystonea regia 102000.0 4 PMID:17768354 -1.11.1.7 * ruegeria pomeroyi dss-3 54000.0 2 PMID:17395199 -1.11.1.7 * sclerocarya birrea 71000.0 1 * -1.11.1.7 * solanum lycopersicum 142000.0 6 PMID:14521509;PMID:16660701 -1.11.1.7 * sorghum bicolor 38000.0 2 PMID:16650004 -1.11.1.7 * streptomyces thermoviolaceus 82000.0 2 * -1.11.1.7 * sus scrofa 51000.0 2 PMID:7138501 -1.11.1.7 * trachycarpus fortunei 50000.0 1 PMID:17177516 -1.11.1.7 * triticum aestivum 136000.0 3 PMID:19183290 -1.11.1.7 * yersinia pseudotuberculosis 17590.0 1 PMID:21139206 -1.11.1.8 * homo sapiens 240000.0 13 PMID:10446374;PMID:10958306;PMID:19669106;PMID:23668778;PMID:8864829;PMID:8938592;PMID:9360536;PMID:9492031 -1.11.1.8 * sus scrofa 135000.0 3 PMID:12325367;PMID:3965458;PMID:6503722 -1.11.1.9 * aloe vera 62000.0 2 PMID:8193675 -1.11.1.9 * bos taurus 85500.0 7 PMID:17437091;PMID:435246;PMID:5549561;PMID:6714945;PMID:7329310;PMID:921274;PMID:974099 -1.11.1.9 * brugia pahangi 29000.0 1 PMID:7629152 -1.11.1.9 * camelus dromedarius 69000.0 1 * -1.11.1.9 * cryptosporidium parvum 25000.0 1 PMID:24477026 -1.11.1.9 * equus caballus 34000.0 2 PMID:17714875 -1.11.1.9 * gallus gallus 19500.0 1 PMID:8842471 -1.11.1.9 * homo sapiens 100000.0 5 PMID:17431126;PMID:17714875;PMID:17964641;PMID:435246;PMID:7329310;PMID:8204670;PMID:921274;PMID:974099 -1.11.1.9 * hyalomma dromedarii 72000.0 2 * -1.11.1.9 * lateolabrax japonicus 70000.0 2 PMID:11926531 -1.11.1.9 * mesocricetus auratus 23000.0 1 PMID:6227287 -1.11.1.9 * mus musculus 34000.0 2 PMID:17937614 -1.11.1.9 * oncorhynchus mykiss 100000.0 2 * -1.11.1.9 * oryctolagus cuniculus 80000.0 2 PMID:10549853 -1.11.1.9 * palaemon carinicauda 21350.0 1 PMID:23770349 -1.11.1.9 * piaractus mesopotamicus 92000.0 2 PMID:17544198 -1.11.1.9 * procambarus clarkii 20900.0 1 PMID:23567855 -1.11.1.9 * rattus norvegicus 88000.0 6 PMID:17714875;PMID:17993721;PMID:435246;PMID:7329310;PMID:921274;PMID:974099 -1.11.1.9 * saccharomyces cerevisiae 80000.0 2 PMID:16754991;PMID:34580743 -1.11.1.9 * schistosoma mansoni 19400.0 1 PMID:19714775 -1.11.1.9 * sus scrofa 20000.0 1 PMID:17431126;PMID:17964641 -1.11.1.9 * thunnus maccoyii 85000.0 2 * -1.11.1.9 * unio tumidus 26400.0 1 PMID:16945589 -1.11.2.1 * achaetomiella virescens 52000.0 1 PMID:31980430 -1.11.2.1 * coprinellus radians 45000.0 2 PMID:17601809 -1.11.2.1 * cyclocybe aegerita 46000.0 8 PMID:15294788;PMID:16253244;PMID:16628447;PMID:19434406;PMID:19585533;PMID:19713216;PMID:20516602 -1.11.2.1 * daldinia caldariorum 55000.0 1 PMID:31980430 -1.11.2.1 * marasmius rotula 32000.0 2 PMID:21988939;PMID:29604496 -1.11.2.1 * marasmius wettsteinii 62.0 1 PMID:29604496 -1.11.2.2 * equus caballus 150000.0 1 PMID:9553712 -1.11.2.2 * homo sapiens 150000.0 12 PMID:11513872;PMID:11589706;PMID:1315274;PMID:1851479;PMID:29585927;PMID:6091622;PMID:9359420 -1.11.2.2 * raphanus sativus 54500.0 2 * -1.11.2.2 * scophthalmus maximus 150000.0 1 PMID:33412231 -1.11.2.3 * arabidopsis thaliana 32000.0 4 PMID:16956885;PMID:19467604;PMID:22913587 -1.11.2.3 * avena sativa 27000.0 1 PMID:16956885 -1.11.2.3 * lathyrus oleraceus 230000.0 3 PMID:468835 -1.11.2.3 * soja hispida 37000.0 1 PMID:11266599 -1.11.2.3 * solanum lycopersicum 28000.0 2 * -1.11.2.4 * bacillus subtilis 48000.0 1 PMID:11914497;PMID:17706598 -1.11.2.4 * clostridium acetobutylicum 48000.0 1 PMID:11914497;PMID:17706598 -1.11.2.4 * fusarium oxysporum 118000.0 2 PMID:10995755 -1.11.2.5 * streptomyces lavendulae 39854.0 2 PMID:22187429 -1.12.1.2 * caldanaerobacter subterraneus subsp. tengcongensis 162500.0 5 PMID:15256587 -1.12.1.2 * cupriavidus necator 206000.0 10 PMID:10682839;PMID:186126;PMID:2188945 -1.12.1.2 * rhodococcus opacus 200000.0 6 * -1.12.1.2 * synechocystis sp. 375000.0 3 PMID:12034472 -1.12.1.2 * thermococcus stetteri 106000.0 1 * -1.12.1.3 * pyrococcus furiosus 150000.0 2 PMID:20463892;PMID:30307115 -1.12.1.3 * solidesulfovibrio fructosivorans 19000.0 3 PMID:12460679;PMID:9485416 -1.12.1.3 * tetradesmus obliquus 55000.0 1 PMID:11115639 -1.12.1.3 * thermococcus kodakarensis 440000.0 1 PMID:12591889 -1.12.1.4 * neomoorella thermoacetica 300000.0 4 PMID:23316038 -1.12.1.4 * ruminococcus albus 68000.0 3 PMID:25157086 -1.12.1.4 * thermotoga maritima 160000.0 8 PMID:11265464 -1.12.1.5 * pyrococcus furiosus 320000.0 5 PMID:10714990 -1.12.2.1 * bacteria 58000.0 1 * -1.12.2.1 * desulfovibrio desulfuricans 76000.0 9 PMID:11170458;PMID:5650411;PMID:6096145;PMID:6303306 -1.12.2.1 * megalodesulfovibrio gigas 89500.0 6 PMID:17847093;PMID:6093686 -1.12.2.1 * nitratidesulfovibrio vulgaris 89000.0 6 PMID:15780995;PMID:16187073;PMID:181372 -1.12.2.1 * thiocapsa roseopersicina 68000.0 3 * -1.12.5.1 * bradyrhizobium japonicum 82600.0 3 PMID:8354459 -1.12.5.1 * mycolicibacterium smegmatis 900000.0 1 * -1.12.5.1 * wolinella succinogenes 63866.0 6 PMID:1587288;PMID:8319698 -1.12.7.2 * acidithiobacillus ferrooxidans 100000.0 3 PMID:8661919 -1.12.7.2 * alvikia littoralis 57000.0 2 PMID:9989593 -1.12.7.2 * caldanaerobacter subterraneus subsp. tengcongensis 69000.0 5 PMID:15256587 -1.12.7.2 * chlamydomonas moewusii 45400.0 1 PMID:19904421 -1.12.7.2 * chlamydomonas reinhardtii 48000.0 6 PMID:16663691;PMID:19904421;PMID:8513797 -1.12.7.2 * chlorococcum submarinum 45300.0 1 PMID:19904421 -1.12.7.2 * clostridium acetobutylicum 64300.0 1 PMID:19904421 -1.12.7.2 * clostridium pasteurianum 63800.0 6 PMID:19904421;PMID:4326766;PMID:4433567;PMID:6331453 -1.12.7.2 * desulfomicrobium baculatum 49000.0 2 PMID:10378275 -1.12.7.2 * desulfovibrio desulfuricans 46100.0 2 PMID:19904421 -1.12.7.2 * enterobacter cloacae 50800.0 2 * -1.12.7.2 * megasphaera elsdenii 53600.0 3 PMID:19904421;PMID:527582 -1.12.7.2 * methanococcus maripaludis 360000.0 2 PMID:20511510 -1.12.7.2 * methanosarcina barkeri 98000.0 3 * -1.12.7.2 * nitratidesulfovibrio vulgaris 66400.0 2 PMID:9367885 -1.12.7.2 * pyrococcus furiosus 320000.0 16 PMID:10714990;PMID:10852873;PMID:11054105;PMID:24860091;PMID:2538471;PMID:25476267 -1.12.7.2 * scenedesmus fuscus 45100.0 1 PMID:19904421 -1.12.7.2 * sporomusa sphaeroides 130000.0 4 PMID:8593101 -1.12.7.2 * tetradesmus obliquus 44600.0 3 PMID:11096090;PMID:19904421 -1.12.7.2 * tetraselmis sp. ksn-2002 89000.0 3 PMID:17321121 -1.12.98.1 * methanobacterium formicicum 790000.0 7 PMID:2738024;PMID:3301819;PMID:6375661 -1.12.98.1 * methanocaldococcus jannaschii 990000.0 2 PMID:16348172;PMID:3663585;PMID:3804976 -1.12.98.1 * methanococcus vannielii 340000.0 1 PMID:6211447 -1.12.98.1 * methanococcus voltae 745000.0 2 PMID:3121317 -1.12.98.1 * methanosarcina barkeri 845000.0 8 PMID:2550229;PMID:8521835 -1.12.98.1 * methanospirillum hungatei 720000.0 3 * -1.12.98.1 * methanothermobacter thermautotrophicus 960000.0 12 PMID:16348172;PMID:17007434;PMID:3663585;PMID:3804976;PMID:6300837;PMID:7061485;PMID:8002593 -1.12.98.2 * methanocaldococcus jannaschii 38000.0 1 PMID:19671178 -1.12.98.2 * methanopyrus kandleri 170000.0 2 PMID:1772345 -1.12.98.2 * methanothermobacter marburgensis 43000.0 3 PMID:14686932;PMID:15506791 -1.12.98.2 * methanothermobacter thermautotrophicus 45000.0 2 PMID:1765081;PMID:8383041 -1.12.98.2 * methanothermobacter wolfeii 92000.0 2 PMID:1521540 -1.12.98.2 * methanothermococcus thermolithotrophicus 150000.0 4 PMID:8599536 -1.12.98.3 * methanosarcina barkeri 60000.0 4 PMID:10471795;PMID:10491189 -1.12.98.3 * methanosarcina mazei 60000.0 2 PMID:10471795 -1.12.98.4 * acidithiobacillus ferrooxidans 120000.0 1 PMID:16232842 -1.12.98.4 * pyrococcus furiosus 320000.0 7 PMID:10714990;PMID:7615063 -1.12.98.4 * pyrodictium abyssi 52000.0 1 PMID:11265482;PMID:9546664 -1.12.98.4 * rhodobacter capsulatus 85033.0 1 PMID:8890912 -1.12.98.4 * thermophilic iron-oxidizing bacterium strain ti-1 86000.0 2 PMID:9614700 -1.12.98.4 * wolinella succinogenes 200000.0 2 * -1.12.99.6 * acidianus ambivalens 66000.0 2 PMID:12949162 -1.12.99.6 * aeropyrum camini 85000.0 1 PMID:19716518 -1.12.99.6 * afipia carboxidovorans 128000.0 6 PMID:9324252 -1.12.99.6 * allochromatium vinosum 52000.0 2 PMID:16969669 -1.12.99.6 * chlamydomonas reinhardtii 49000.0 2 PMID:19435321;PMID:19855833 -1.12.99.6 * clostridium pasteurianum 60000.0 2 PMID:3015247 -1.12.99.6 * cupriavidus necator 165000.0 4 PMID:11278570;PMID:30110155 -1.12.99.6 * desulfovibrio desulfuricans 53500.0 3 PMID:1327776 -1.12.99.6 * desulfovibrio multispirans 82000.0 3 PMID:6097250 -1.12.99.6 * enterobacter cloacae 16000.0 1 PMID:15474481 -1.12.99.6 * escherichia coli 200000.0 6 PMID:10803945;PMID:17668201;PMID:3516689;PMID:3894325 -1.12.99.6 * hydrogenibacillus schlegelii 100000.0 3 PMID:19025569 -1.12.99.6 * hydrogenimonas thermophila 86300.0 2 PMID:20699572 -1.12.99.6 * hydrogenobacter thermophilus 200000.0 3 PMID:10803945;PMID:3516689 -1.12.99.6 * hydrogenophaga sp. 100000.0 3 PMID:19025569 -1.12.99.6 * lamprobacter modestohalophilus 64000.0 2 PMID:15000682 -1.12.99.6 * lyngbya majuscula 60000.0 1 PMID:19222582 -1.12.99.6 * megalodesulfovibrio gigas 69004.0 5 PMID:12804572 -1.12.99.6 * megasphaera elsdenii 52000.0 1 PMID:3015247 -1.12.99.6 * methanocaldococcus jannaschii 76000.0 2 PMID:17924153 -1.12.99.6 * nitratidesulfovibrio vulgaris 87000.0 4 PMID:3015247;PMID:7652207 -1.12.99.6 * nostoc punctiforme 60000.0 1 PMID:19222582 -1.12.99.6 * nostoc sp. 60000.0 1 PMID:19222582 -1.12.99.6 * pyrococcus furiosus 320000.0 9 PMID:10714990;PMID:2538471 -1.12.99.6 * tetraselmis sp. ksn-2002 70000.0 2 PMID:17321121 -1.12.99.6 * thermococcus kodakarensis 96600.0 2 PMID:22138400 -1.12.99.6 * thermodesulfobacterium thermophilum 55000.0 2 PMID:1317168 -1.13.11.1 * acinetobacter calcoaceticus 85000.0 3 PMID:2280696;PMID:58860 -1.13.11.1 * acinetobacter radioresistens 112400.0 8 PMID:11307956;PMID:9369233 -1.13.11.1 * acinetobacter sp. 66000.0 1 PMID:22754009 -1.13.11.1 * arthrobacter sp. 72000.0 3 PMID:9760749 -1.13.11.1 * brevibacterium fuscum 78000.0 1 PMID:14056355 -1.13.11.1 * burkholderia cepacia 33000.0 1 PMID:20040374;PMID:31723074 -1.13.11.1 * candida albicans 64000.0 2 PMID:17089147;PMID:3214177 -1.13.11.1 * candida maltosa 65000.0 2 * -1.13.11.1 * corynebacterium glutamicum 63500.0 2 PMID:15168857 -1.13.11.1 * cupriavidus campinensis 34000.0 1 PMID:31900038 -1.13.11.1 * cupriavidus necator 76000.0 2 PMID:8661943 -1.13.11.1 * cutaneotrichosporon cutaneum 105000.0 2 * -1.13.11.1 * frateuria sp. 140000.0 4 * -1.13.11.1 * geobacillus sp. 96000.0 1 * -1.13.11.1 * pseudomonas aeruginosa 22000.0 1 * -1.13.11.1 * pseudomonas fluorescens 83000.0 1 PMID:13502352 -1.13.11.1 * pseudomonas putida 90000.0 16 PMID:14599591;PMID:17089147;PMID:2295613;PMID:3214177;PMID:475379;PMID:6029438 -1.13.11.1 * pseudomonas reinekei 34233.0 3 PMID:17172348 -1.13.11.1 * pseudomonas sp. 82000.0 2 PMID:697765 -1.13.11.1 * ralstonia sp. 31000.0 2 PMID:11676005 -1.13.11.1 * rhizobium leguminosarum 107000.0 4 PMID:16348234 -1.13.11.1 * rhodococcus erythropolis 150000.0 3 * -1.13.11.1 * rhodococcus opacus 33000.0 1 PMID:20040374;PMID:31723074 -1.13.11.1 * rhodococcus rhodnii 70000.0 2 PMID:10424908 -1.13.11.1 * rhodococcus rhodochrous 120000.0 6 PMID:10424908;PMID:16348234 -1.13.11.1 * rhodococcus sp. (in: high g+c gram-positive bacteria) 33000.0 2 PMID:16233669 -1.13.11.1 * sphingobium xenophagum 35000.0 1 * -1.13.11.1 * stenotrophomonas maltophilia 34500.0 1 PMID:23536173 -1.13.11.1 * stutzerimonas stutzeri 107000.0 1 PMID:32582076 -1.13.11.11 * homo sapiens 192000.0 3 PMID:34074763 -1.13.11.12 * burkholderia thailandensis 150000.0 1 PMID:25586578 -1.13.11.12 * fusarium oxysporum 160000.0 2 PMID:23741422 -1.13.11.12 * glycine max 101000.0 1 PMID:32732043 -1.13.11.12 * hordeum vulgare 106000.0 1 PMID:9492266 -1.13.11.12 * lasiodiplodia theobromae 93000.0 2 PMID:25326184 -1.13.11.12 * nostoc punctiforme 70891.0 1 PMID:17412376 -1.13.11.12 * olea europaea 103400.0 5 PMID:18790508;PMID:19268561;PMID:19722522 -1.13.11.12 * oryza sativa 105000.0 1 PMID:18185911 -1.13.11.12 * pseudomonas aeruginosa 70000.0 1 PMID:23064455 -1.13.11.15 * arthrobacter synephrinum 282000.0 1 PMID:588248 -1.13.11.15 * brevibacillus brevis 140000.0 3 PMID:6270137 -1.13.11.15 * brevibacterium fuscum 220000.0 3 PMID:8621411 -1.13.11.15 * escherichia coli 33000.0 1 PMID:2261999 -1.13.11.15 * geobacillus stearothermophilus 106000.0 1 PMID:838683 -1.13.11.15 * klebsiella pneumoniae 102000.0 2 * -1.13.11.15 * pseudomonas aeruginosa 112200.0 1 PMID:28158217 -1.13.11.15 * pseudomonas putida 138000.0 3 PMID:19416;PMID:4770367;PMID:4837446 -1.13.11.16 * achromobacter sp. 70000.0 1 PMID:5729960 -1.13.11.16 * escherichia coli 134000.0 2 PMID:8399388 -1.13.11.17 * tecoma stans 58000.0 1 PMID:16662784 -1.13.11.17 * zea mays 98000.0 1 * -1.13.11.18 * acidianus brierleyi 560000.0 2 * -1.13.11.18 * acidianus sp. 35000.0 1 PMID:12664265 -1.13.11.18 * acidithiobacillus caldus 99400.0 2 PMID:30072973 -1.13.11.18 * acidithiobacillus ferrooxidans 46000.0 1 PMID:12855721 -1.13.11.18 * acidithiobacillus thiooxidans 46000.0 1 PMID:12855721 -1.13.11.18 * paraburkholderia phytofirmans 40000.0 1 PMID:28684420 -1.13.11.18 * staphylococcus aureus 226000.0 1 PMID:26177047 -1.13.11.19 * equus caballus 100000.0 6 PMID:5477299;PMID:5912113 -1.13.11.19 * sus scrofa 64000.0 1 PMID:3657558 -1.13.11.2 * acinetobacter sp. 147000.0 2 PMID:17617714 -1.13.11.2 * cupriavidus necator 34000.0 1 PMID:9588193 -1.13.11.2 * geobacillus thermoleovorans 135000.0 2 PMID:10484174 -1.13.11.2 * halalkalibacterium ligniniphilum 34000.0 4 PMID:34907211 -1.13.11.2 * oceanimonas marisflavi 69200.0 1 * -1.13.11.2 * pseudomonas aeruginosa 144600.0 4 PMID:2126328 -1.13.11.2 * pseudomonas putida 144000.0 11 PMID:14087325;PMID:18023805;PMID:19416;PMID:20038148;PMID:29380863;PMID:5127383;PMID:7629031 -1.13.11.2 * pseudomonas putida mt-2 140000.0 2 PMID:6826545 -1.13.11.2 * pseudomonas sp. 150000.0 8 PMID:12519074;PMID:15322368;PMID:15347689;PMID:15583170;PMID:15730028;PMID:17617714;PMID:9614705 -1.13.11.2 * rhodococcus sp. 2g 47000.0 2 PMID:32036315 -1.13.11.2 * sphingomonas sp. 150000.0 2 PMID:12519074 -1.13.11.2 * stutzerimonas stutzeri 117000.0 4 PMID:15347689;PMID:15583170 -1.13.11.2 * thauera sp. k11 140000.0 1 PMID:29380863;PMID:5127383 -1.13.11.20 * arabidopsis thaliana 36513.0 2 PMID:28332493 -1.13.11.20 * cupriavidus necator 63900.0 2 PMID:26590284 -1.13.11.20 * cyprinus carpio 23500.0 1 PMID:19633968 -1.13.11.20 * histoplasma capsulatum 10500.0 1 PMID:6838822 -1.13.11.20 * homo sapiens 70000.0 1 PMID:12110289 -1.13.11.20 * rattus norvegicus 68000.0 16 PMID:11287364;PMID:14752623;PMID:15623508;PMID:16325423;PMID:17327371;PMID:19011731;PMID:21039937;PMID:2334417;PMID:2821347;PMID:632231;PMID:9824269 -1.13.11.20 * trichophyton mentagrophytes 23060.0 2 PMID:19011731;PMID:21039937 -1.13.11.24 * aspergillus flavus 111400.0 3 PMID:19069847;PMID:5555519;PMID:5579942 -1.13.11.24 * aspergillus niger 135000.0 4 PMID:10469153 -1.13.11.24 * bacillus subtilis 40000.0 2 PMID:15039076;PMID:20460727 -1.13.11.24 * penicillium olsonii 56000.0 2 PMID:18206655 -1.13.11.24 * streptomyces sp. 65100.0 7 PMID:17516049;PMID:18950192 -1.13.11.25 * prescottella equi 286000.0 2 PMID:5506273 -1.13.11.26 * triticum aestivum 25000.0 1 PMID:3699018 -1.13.11.27 * arabidopsis sp. 100000.0 1 PMID:10198110 -1.13.11.27 * arabidopsis thaliana 48650.0 1 PMID:16681377 -1.13.11.27 * daucus carota 48094.0 2 PMID:10858299 -1.13.11.27 * gallus gallus 97000.0 2 PMID:1158879;PMID:3037256 -1.13.11.27 * homo sapiens 87000.0 5 PMID:17613;PMID:23950902;PMID:3037254;PMID:873932 -1.13.11.27 * pseudomonas fluorescens 40000.0 2 PMID:17207262 -1.13.11.27 * pseudomonas sp. 150000.0 2 PMID:3037255;PMID:889802 -1.13.11.27 * rattus norvegicus 44000.0 1 PMID:12867153 -1.13.11.27 * salvia miltiorrhiza 52540.0 1 PMID:19011990 -1.13.11.27 * sphingobium sp. 40000.0 1 PMID:31884791 -1.13.11.27 * sus scrofa 89000.0 5 PMID:3298972;PMID:7103516 -1.13.11.29 * stizolobium hassjoo 45000.0 1 PMID:624278 -1.13.11.3 * acinetobacter calcoaceticus 677000.0 1 PMID:1252412 -1.13.11.3 * acinetobacter lwoffii 26000.0 2 PMID:12127980 -1.13.11.3 * aspergillus niger 63230.0 1 PMID:31540981 -1.13.11.3 * azotobacter vinelandii 510000.0 4 PMID:6766312 -1.13.11.3 * brevibacterium fuscum 315000.0 3 PMID:2280720;PMID:6323474 -1.13.11.3 * burkholderia cepacia 198000.0 3 PMID:6548751 -1.13.11.3 * ectopseudomonas oleovorans 189900.0 3 * -1.13.11.3 * geobacillus sp. 480000.0 1 * -1.13.11.3 * hydrogenophaga palleronii 27097.0 2 PMID:11454212 -1.13.11.3 * nocardia erythropolis 150000.0 1 * -1.13.11.3 * pseudomonas aeruginosa 783100.0 3 PMID:4967959;PMID:6776106 -1.13.11.3 * pseudomonas putida 590000.0 8 PMID:3116260;PMID:6273403 -1.13.11.3 * rhizobium leguminosarum 220000.0 3 * -1.13.11.3 * rhizobium sp. lmb-1 500000.0 1 PMID:28516418 -1.13.11.3 * sagittula stellata 26700.0 2 PMID:11055908 -1.13.11.3 * tecoma stans 150000.0 1 * -1.13.11.30 * stizolobium hassjoo 45000.0 1 PMID:624278 -1.13.11.31 * bos taurus 72000.0 1 PMID:2295656;PMID:3782139 -1.13.11.31 * gersemia fruticosa 77000.0 1 PMID:16321357 -1.13.11.31 * homo sapiens 76500.0 1 PMID:18155727 -1.13.11.31 * rattus norvegicus 75305.0 1 PMID:8117750 -1.13.11.31 * sus scrofa 74700.0 2 PMID:19683507;PMID:2295656;PMID:3782139 -1.13.11.33 * crocosphaera subtropica atcc 51142 65000.0 1 PMID:20223828 -1.13.11.33 * homo sapiens 76000.0 7 PMID:16239596;PMID:1662607;PMID:16874012;PMID:17040969;PMID:26216303;PMID:3356688;PMID:8334154 -1.13.11.33 * hordeum vulgare 106000.0 1 PMID:9492266 -1.13.11.33 * nostoc punctiforme 70891.0 1 PMID:17412376 -1.13.11.33 * oncorhynchus mykiss 70000.0 1 * -1.13.11.33 * oryctolagus cuniculus 78000.0 4 PMID:111925;PMID:16239596;PMID:17040969;PMID:6813644;PMID:9790886 -1.13.11.33 * sus scrofa 81000.0 1 PMID:16049159 -1.13.11.34 * homo sapiens 80000.0 3 PMID:12432920;PMID:20860670;PMID:25107828 -1.13.11.34 * mus musculus 75000.0 2 PMID:3012557 -1.13.11.34 * rattus norvegicus 73000.0 1 PMID:12432920 -1.13.11.34 * solanum tuberosum 92000.0 3 PMID:2233349 -1.13.11.34 * sus scrofa 72000.0 1 PMID:12432920;PMID:2233351;PMID:3086322 -1.13.11.34 * tulipa hybrid cultivar 83000.0 1 PMID:3144972 -1.13.11.36 * phenylobacterium immobile 220000.0 3 PMID:19349 -1.13.11.37 * arthrobacter sp. 79000.0 2 PMID:10380628 -1.13.11.37 * azotobacter sp. 58000.0 2 PMID:16535063 -1.13.11.37 * burkholderia cepacia 68000.0 2 PMID:8900023 -1.13.11.37 * cutaneotrichosporon cutaneum 93000.0 3 PMID:6539772 -1.13.11.37 * pimelobacter simplex 65000.0 1 * -1.13.11.37 * pseudarthrobacter chlorophenolicus a6 42000.0 2 PMID:16269679 -1.13.11.37 * pseudomonas sp. 34800.0 1 PMID:20361240 -1.13.11.37 * rhodococcus opacus 33200.0 1 PMID:15262926 -1.13.11.37 * streptomyces rochei 61000.0 2 PMID:7798136 -1.13.11.38 * nocardioides sp. 270000.0 4 PMID:9335300;PMID:9525941 -1.13.11.38 * pseudaminobacter salicylatoxidans 185000.0 2 PMID:11698383 -1.13.11.38 * pseudarthrobacter phenanthrenivorans 180000.0 6 PMID:22101055 -1.13.11.38 * pseudomonas sp. 160000.0 2 PMID:19574301 -1.13.11.39 * bacillus sp. (in: firmicutes) 125000.0 4 PMID:12672826;PMID:20208161;PMID:22342724 -1.13.11.39 * comamonas sp. 32000.0 1 PMID:21113668 -1.13.11.39 * delftia acidovorans 170000.0 1 PMID:27784944 -1.13.11.39 * ectopseudomonas oleovorans 250000.0 3 PMID:3100508 -1.13.11.39 * metapseudomonas resinovorans 78000.0 3 PMID:12728990 -1.13.11.39 * pseudomonas putida 270000.0 5 PMID:8633883;PMID:9228766 -1.13.11.39 * pseudomonas sp. 265000.0 3 PMID:8428946 -1.13.11.39 * rhodococcus globerulus 120000.0 5 PMID:12700274;PMID:8126007 -1.13.11.39 * rhodococcus pyridinivorans 220000.0 4 PMID:18585431 -1.13.11.39 * rhodococcus rhodochrous 32000.0 1 PMID:21113668 -1.13.11.39 * rhodococcus sp. (in: high g+c gram-positive bacteria) 300000.0 2 PMID:8702287 -1.13.11.39 * uncultured bacterium 32000.0 1 PMID:21898128 -1.13.11.4 * aquipseudomonas alcaligenes 154000.0 4 PMID:10049846;PMID:16930152;PMID:17720458;PMID:234947 -1.13.11.4 * comamonas testosteroni 158000.0 2 PMID:2156846 -1.13.11.4 * corynebacterium glutamicum 180000.0 2 PMID:16000747 -1.13.11.4 * delftia acidovorans 164000.0 1 PMID:2156846 -1.13.11.4 * escherichia coli 154000.0 3 PMID:10049846;PMID:16930152;PMID:234947 -1.13.11.4 * faucicola osloensis 154000.0 2 PMID:10049846;PMID:16930152;PMID:234947 -1.13.11.4 * geobacillus stearothermophilus 40000.0 1 * -1.13.11.4 * haloferax sp. 174000.0 2 PMID:9827334 -1.13.11.4 * klebsiella pneumoniae 159000.0 3 PMID:16427517;PMID:8807807 -1.13.11.4 * martelella sp. ad-3 120000.0 1 PMID:26394696 -1.13.11.4 * pseudaminobacter salicylatoxidans 185000.0 4 PMID:11698383;PMID:15220336 -1.13.11.4 * pseudomonas putida 82000.0 3 PMID:10049846 -1.13.11.4 * ralstonia solanacearum 38000.0 1 * -1.13.11.4 * ralstonia sp. 35000.0 1 PMID:16427517 -1.13.11.4 * rhizorhabdus dicambivorans 70000.0 1 PMID:32786824 -1.13.11.4 * rhodococcus erythropolis 328000.0 2 * -1.13.11.4 * rhodococcus opacus 177000.0 2 PMID:33122105 -1.13.11.4 * ruegeria pomeroyi 132000.0 2 PMID:17684705 -1.13.11.4 * sphingomonas sp. 177000.0 2 PMID:9696766 -1.13.11.4 * xanthobacter polyaromaticivorans 146000.0 4 PMID:17213679 -1.13.11.40 * plexaura homomalla 100000.0 2 PMID:8702854 -1.13.11.41 * alcaligenes sp. 87000.0 8 PMID:10567221;PMID:26457516 -1.13.11.41 * burkholderia sp. 90000.0 2 PMID:22451401 -1.13.11.43 * sphingomonas paucimobilis 110000.0 7 PMID:7763880;PMID:8534977;PMID:9339561 -1.13.11.45 * gaeumannomyces graminis 160000.0 3 PMID:9582345 -1.13.11.46 * amycolatopsis orientalis 80000.0 2 * -1.13.11.47 * arthrobacter sp. 32000.0 1 PMID:8856057 -1.13.11.47 * pseudomonas putida 30000.0 2 PMID:1515060;PMID:8856057 -1.13.11.48 * arthrobacter sp. 32000.0 1 PMID:8856057 -1.13.11.48 * paenarthrobacter nitroguajacolicus 33240.0 1 PMID:18549245 -1.13.11.49 * azospira oryzae 155000.0 9 PMID:19361444;PMID:26218477;PMID:33113038;PMID:8929278 -1.13.11.49 * dechloromonas agitata 116000.0 2 PMID:18422344 -1.13.11.49 * ideonella dechloratans 115000.0 2 PMID:11472023 -1.13.11.49 * magnetospirillum sp. 140000.0 1 PMID:26218477;PMID:33113038;PMID:8929278 -1.13.11.49 * stutzerimonas chloritidismutans 110000.0 2 PMID:19228194 -1.13.11.5 * arabidopsis thaliana 199000.0 2 PMID:22980205 -1.13.11.5 * aspergillus nidulans 50168.0 1 PMID:7673153 -1.13.11.5 * aspergillus niger 200000.0 1 * -1.13.11.5 * bos taurus 254000.0 1 PMID:10876237 -1.13.11.5 * homo sapiens 480000.0 3 PMID:10876237;PMID:15479158;PMID:8581831 -1.13.11.5 * mus musculus 480000.0 5 PMID:10876237;PMID:7705358;PMID:8581831;PMID:9069115 -1.13.11.5 * oryctolagus cuniculus 480000.0 1 PMID:8581831 -1.13.11.5 * phanerodontia chrysosporium 52900.0 1 PMID:16217726 -1.13.11.5 * pseudomonas fluorescens 380000.0 1 PMID:5954067 -1.13.11.5 * pseudomonas putida 48000.0 1 PMID:16470664 -1.13.11.50 * acinetobacter johnsonii 66430.0 9 PMID:12237107;PMID:12379146;PMID:15934927;PMID:16131208;PMID:18973472 -1.13.11.51 * arachis hypogaea 66860.0 1 PMID:16147878 -1.13.11.51 * nostoc sp. pcc 7120 = fachb-418 55000.0 1 PMID:18485074 -1.13.11.51 * saccharum hybrid cultivar 65900.0 1 * -1.13.11.52 * aedes aegypti 42000.0 1 PMID:17212352 -1.13.11.52 * anopheles gambiae 47900.0 1 PMID:18687401 -1.13.11.52 * azumapecten farreri 44800.0 1 * -1.13.11.52 * brevibacillus brevis 27000.0 1 PMID:6712960 -1.13.11.52 * ctenopharyngodon idella 49000.0 1 PMID:30965085 -1.13.11.52 * cupriavidus metallidurans 120000.0 1 PMID:19290871 -1.13.11.52 * delftia acidovorans 123000.0 4 PMID:4307451 -1.13.11.52 * drosophila melanogaster 190000.0 1 PMID:19290871 -1.13.11.52 * homo sapiens 320000.0 12 PMID:10833386;PMID:11180976;PMID:11912287;PMID:12766158;PMID:17320464;PMID:18715787;PMID:19290871;PMID:19767648;PMID:20435158;PMID:20691806;PMID:20815922;PMID:20955343;PMID:22594922;PMID:24105077;PMID:2428037 -1.13.11.52 * mus musculus 150000.0 7 PMID:11180976;PMID:11912287;PMID:12766158;PMID:1937018;PMID:20140689;PMID:20815922;PMID:24105077;PMID:6783035 -1.13.11.52 * oryctolagus cuniculus 190000.0 6 PMID:19290871;PMID:26687;PMID:931956 -1.13.11.52 * protophormia terraenovae 120000.0 1 PMID:2536 -1.13.11.52 * rattus norvegicus 180000.0 7 PMID:20435158;PMID:20955343;PMID:2372286;PMID:4626718;PMID:8354392 -1.13.11.52 * saccharomyces cerevisiae 190000.0 1 PMID:19290871 -1.13.11.52 * xanthomonas campestris 120000.0 1 PMID:19290871 -1.13.11.53 * klebsiella pneumoniae 20250.0 3 PMID:11371200;PMID:8407993;PMID:9880484 -1.13.11.53 * mus musculus 26000.0 3 PMID:16783794;PMID:26858196 -1.13.11.53 * solanum tuberosum 23700.0 1 PMID:18776203 -1.13.11.54 * klebsiella oxytoca 20240.0 1 PMID:11371200;PMID:9880484 -1.13.11.54 * klebsiella pneumoniae 20240.0 2 PMID:11371200;PMID:9880484 -1.13.11.54 * mus musculus 26000.0 1 PMID:26858196 -1.13.11.54 * trypanosoma cruzi 43000.0 1 PMID:29530564 -1.13.11.55 * acidianus ambivalens 871000.0 11 PMID:15030315;PMID:1522063;PMID:15698962;PMID:16391031;PMID:2493451 -1.13.11.55 * acidianus sp. 35000.0 1 PMID:11111027;PMID:12664265 -1.13.11.55 * acidianus tengchongensis 35173.0 2 PMID:11111027;PMID:12664265 -1.13.11.55 * aquifex aeolicus 602000.0 4 PMID:18060346;PMID:27920296 -1.13.11.55 * sulfobacillus acidophilus 35000.0 1 PMID:23726793 -1.13.11.55 * sulfurisphaera tokodaii 539000.0 1 PMID:32775998 -1.13.11.55 * thioalkalivibrio paradoxus 556000.0 1 PMID:27920296 -1.13.11.56 * pseudomonas putida 275000.0 2 PMID:7204331 -1.13.11.56 * sphingobium xenophagum 290000.0 2 PMID:2050635 -1.13.11.57 * pseudomonas putida 132000.0 4 PMID:16030014;PMID:21219457 -1.13.11.57 * sphingobium sp. 93800.0 1 PMID:19923743 -1.13.11.57 * sphingomonas paucimobilis 86000.0 3 PMID:16030198 -1.13.11.58 * cynanchum gracillimum 110700.0 2 PMID:22312270 -1.13.11.58 * hordeum vulgare 93200.0 2 PMID:1554746 -1.13.11.58 * musa acuminata 85000.0 1 PMID:16608245 -1.13.11.58 * nicotiana benthamiana 97400.0 1 PMID:21450085 -1.13.11.58 * prunus dulcis 98000.0 1 PMID:11231304 -1.13.11.58 * zea mays 99100.0 1 PMID:20349083 -1.13.11.6 * bos taurus 34000.0 6 PMID:12672479;PMID:1387;PMID:19226621 -1.13.11.6 * homo sapiens 36000.0 1 PMID:12007609 -1.13.11.6 * mus musculus 33000.0 1 PMID:10037484 -1.13.11.6 * papio ursinus 40000.0 1 * -1.13.11.6 * pseudomonas fluorescens 23800.0 2 PMID:12620844 -1.13.11.6 * rattus norvegicus 38000.0 4 PMID:3112306;PMID:7514594;PMID:8906308 -1.13.11.60 * aspergillus nidulans 440000.0 2 PMID:19286665 -1.13.11.60 * colletotrichum gloeosporioides 510000.0 2 PMID:26577673 -1.13.11.60 * gaeumannomyces graminis 520000.0 4 PMID:10497176;PMID:10667399;PMID:8662736 -1.13.11.60 * penicillium oxalicum 370000.0 1 PMID:30342100 -1.13.11.61 * nostoc sp. 156000.0 2 PMID:18031288;PMID:26379279 -1.13.11.63 * galleria mellonella 64000.0 2 PMID:19020100 -1.13.11.63 * gallus gallus 240000.0 5 PMID:11237856;PMID:18979213;PMID:20599666 -1.13.11.63 * homo sapiens 230000.0 9 PMID:11960992;PMID:18004512;PMID:18154347;PMID:18295589;PMID:20599666;PMID:23727499;PMID:24187135 -1.13.11.63 * mus musculus 65000.0 6 PMID:11092891;PMID:17687551;PMID:20599666 -1.13.11.63 * rattus norvegicus 64000.0 1 PMID:16699835 -1.13.11.63 * uncultured marine bacterium 64000.0 2 PMID:19366683 -1.13.11.66 * cupriavidus necator 34000.0 1 PMID:20386911 -1.13.11.66 * pseudomonas fluorescens 112000.0 3 PMID:18502867 -1.13.11.66 * pseudomonas putida 38000.0 2 PMID:20466541 -1.13.11.66 * pseudomonas sp. 18000.0 1 PMID:22380602 -1.13.11.66 * sphingobium chlorophenolicum 36522.0 1 PMID:10387005 -1.13.11.66 * sphingomonas paucimobilis 36000.0 1 PMID:10542173 -1.13.11.66 * sphingomonas sp. 120000.0 6 PMID:21906340 -1.13.11.74 * comamonas testosteroni 140000.0 8 PMID:15580337;PMID:23143244;PMID:8892823;PMID:9169437 -1.13.11.74 * ectopseudomonas oleovorans 140000.0 3 PMID:23143244;PMID:8892823;PMID:9169437 -1.13.11.74 * pseudomonas sp. 140000.0 3 PMID:23143244;PMID:8892823;PMID:9169437 -1.13.11.76 * comamonas testosteroni 130000.0 3 PMID:15580337 -1.13.11.77 * pseudomonas aeruginosa 50000.0 1 PMID:20075076 -1.13.11.77 * pseudomonas sp. 45000.0 1 PMID:15028873 -1.13.11.79 * priestia megaterium 27300.0 1 PMID:23457476 -1.13.11.79 * rhodobacter capsulatus 25000.0 1 PMID:23457476 -1.13.11.79 * rhodospirillum rubrum 47000.0 2 PMID:17301238 -1.13.11.8 * comamonas testosteroni 180000.0 7 PMID:15650824;PMID:2280721;PMID:5048285;PMID:6317682 -1.13.11.8 * pseudarthrobacter phenanthrenivorans 45000.0 1 PMID:34502555 -1.13.11.8 * pseudomonas sp. k82 54000.0 3 PMID:15357311 -1.13.11.8 * rhizobium leguminosarum 120000.0 2 * -1.13.11.8 * sphingomonas paucimobilis 33254.0 4 PMID:17645527 -1.13.11.80 * streptomyces toyocaensis 354000.0 1 PMID:17507985 -1.13.11.81 * mycobacterium tuberculosis 62300.0 3 PMID:23150985 -1.13.11.82 * novosphingobium aromaticivorans 52000.0 1 PMID:22711425 -1.13.11.84 * crocus sativus 41000.0 2 PMID:12509521 -1.13.11.85 * chondromyces apiculatus 75000.0 1 PMID:32114907 -1.13.11.85 * corallococcus coralloides 71100.0 1 PMID:30377752 -1.13.11.85 * haliangium ochraceum 72100.0 1 PMID:30377752 -1.13.11.85 * myxococcus fulvus 71900.0 1 PMID:30377752 -1.13.11.85 * piscinibacter gummiphilus 74400.0 3 PMID:30215127;PMID:30377752 -1.13.11.85 * steroidobacter cummioxidans 71500.0 2 PMID:28695652;PMID:30377752 -1.13.11.85 * xanthomonas sp. 35y 74700.0 3 PMID:15574940;PMID:28500046 -1.13.11.86 * comamonas thiooxydans 45000.0 1 PMID:29038259 -1.13.11.87 * nocardia farcinica 46800.0 1 PMID:28065456 -1.13.11.87 * piscinibacter gummiphilus 74000.0 4 PMID:30215127;PMID:30377752 -1.13.11.87 * rhodococcus rhodochrous 45200.0 2 PMID:27215318 -1.13.11.87 * streptomyces sp. k30 70000.0 3 PMID:24907333;PMID:25819959;PMID:28695652 -1.13.11.87 * xanthomonas sp. 70000.0 1 PMID:12855168 -1.13.11.87 * xanthomonas sp. 35y 70300.0 2 PMID:28500046;PMID:28695652 -1.13.11.88 * pseudomonas putida 69000.0 1 PMID:17516050 -1.13.11.9 * achromobacter sp. 340000.0 1 PMID:4455192 -1.13.11.9 * pseudomonas putida 242000.0 4 PMID:18678916;PMID:20445257;PMID:5578917 -1.13.11.91 * cupriavidus necator 46800.0 1 PMID:26590284 -1.13.11.92 * lathyrus oleraceus 230000.0 1 PMID:10938370 -1.13.12.13 * oplophorus gracilirostris 106000.0 2 PMID:23792095;PMID:24491536;PMID:25019994;PMID:26746005 -1.13.12.15 * cereibacter sphaeroides 190000.0 1 PMID:18923551 -1.13.12.16 * cyberlindnera mrakii 64000.0 7 PMID:11214;PMID:15582992;PMID:18329375 -1.13.12.16 * fusarium oxysporum 185000.0 2 PMID:22538 -1.13.12.16 * neurospora crassa 80000.0 6 PMID:15582992;PMID:18329375;PMID:9501443 -1.13.12.16 * pseudomonas aeruginosa 37000.0 1 PMID:16682407 -1.13.12.17 * streptomyces longisporoflavus 48000.0 1 PMID:16967980 -1.13.12.18 * lingulaulax polyedra 420000.0 10 PMID:10812605;PMID:12657805;PMID:18264588;PMID:573590;PMID:7197271;PMID:7918642 -1.13.12.18 * noctiluca scintillans 100000.0 1 PMID:17130452 -1.13.12.18 * pyrocystis fusiformis 40000.0 1 PMID:573590 -1.13.12.18 * pyrocystis lunula 40000.0 1 PMID:573590 -1.13.12.19 * pseudomonas savastanoi pv. phaseolicola 39370.0 1 PMID:27749027 -1.13.12.19 * pseudomonas syringae 42000.0 5 PMID:1445325;PMID:1770346 -1.13.12.2 * pseudomonas fluorescens 246000.0 3 PMID:4207122;PMID:5772467;PMID:5911646 -1.13.12.21 * streptomyces glaucescens 37500.0 2 PMID:8329392 -1.13.12.24 * aequorea victoria 26000.0 3 PMID:275832;PMID:29382580;PMID:3858813 -1.13.12.24 * mnemiopsis leidyi 27000.0 2 PMID:29770830;PMID:30012485;PMID:30420427 -1.13.12.3 * pseudomonas savastanoi 85000.0 3 PMID:16593610;PMID:3997822 -1.13.12.4 * mycolicibacterium phlei 370000.0 5 * -1.13.12.4 * mycolicibacterium smegmatis 345000.0 6 PMID:2324094;PMID:8663383;PMID:921754 -1.13.12.5 * clytia gregaria 21610.0 1 PMID:8422928 -1.13.12.5 * gaussia princeps (in: crustaceans) 47000.0 7 PMID:12236345;PMID:17593970;PMID:17981153;PMID:19601604 -1.13.12.5 * oplophorus gracilirostris 19000.0 1 PMID:23274053 -1.13.12.5 * renilla reniformis 44000.0 11 PMID:12797;PMID:17980388;PMID:23274053;PMID:23973867;PMID:4395343 -1.13.12.5 * renilla sp. 30000.0 2 PMID:19063714 -1.13.12.6 * cypridina noctiluca 200000.0 3 PMID:15056888;PMID:17297966;PMID:19805215 -1.13.12.6 * vargula hilgendorfii 68000.0 5 PMID:4433517 -1.13.12.7 * luciola parvula 60353.0 2 PMID:28295969 -1.13.12.7 * photinus pyralis 500000.0 15 PMID:12878037;PMID:17090919;PMID:17181991;PMID:18555523;PMID:19119851;PMID:19661129;PMID:22750581;PMID:22986180;PMID:3821727;PMID:5482267;PMID:7138032;PMID:775940 -1.13.12.7 * pyrocoelia sp. rf-2016 63000.0 1 PMID:27716939 -1.13.12.9 * pseudomonas sp. 140000.0 2 PMID:6885723 -1.13.99.1 * homo sapiens 33000.0 2 PMID:15504367;PMID:16332355;PMID:16634620 -1.13.99.1 * mus musculus 33000.0 4 PMID:15504367;PMID:16330753;PMID:16332355;PMID:16634620;PMID:16880565 -1.13.99.1 * rattus norvegicus 33000.0 7 PMID:15504367;PMID:2226462;PMID:437700 -1.13.99.1 * sporopachydermia lactativora 37000.0 2 PMID:14663824 -1.13.99.1 * sus scrofa 65000.0 3 PMID:11716759;PMID:16332355;PMID:16634620;PMID:7263666 -1.13.99.3 * pseudomonas fluorescens 280000.0 10 PMID:3037258;PMID:500674 -1.13.99.3 * pseudomonas sp. 280000.0 2 PMID:15994 -1.14.11.1 * bos taurus 80000.0 3 PMID:6798936 -1.14.11.1 * homo sapiens 64000.0 2 PMID:6497835;PMID:8504802 -1.14.11.1 * pseudomonas sp. 95000.0 5 PMID:8504802;PMID:861203 -1.14.11.1 * rattus norvegicus 68000.0 3 PMID:10709635;PMID:9546596 -1.14.11.11 * anisodus acutangulus 64000.0 3 PMID:17927905;PMID:21380527 -1.14.11.11 * atropa belladonna 39369.0 2 PMID:22705021 -1.14.11.11 * brugmansia sanguinea 38768.0 2 PMID:30108978 -1.14.11.11 * datura metel 39000.0 1 PMID:20951598 -1.14.11.11 * hyoscyamus niger 41000.0 4 PMID:2033047;PMID:3569262 -1.14.11.11 * hyoscyamus senecionis 39015.0 1 PMID:23786817 -1.14.11.12 * spinacia oleracea 381000.0 1 PMID:16665690 -1.14.11.13 * lathyrus oleraceus 45000.0 4 PMID:16181493;PMID:24241725 -1.14.11.13 * phaseolus vulgaris 42000.0 4 * -1.14.11.13 * solanum lycopersicum 36040.0 1 PMID:17676476 -1.14.11.15 * arabidopsis thaliana 39100.0 1 PMID:16181493 -1.14.11.15 * cucurbita maxima 58000.0 1 * -1.14.11.15 * phaseolus vulgaris 42000.0 1 * -1.14.11.16 * bos taurus 56000.0 4 PMID:1856229;PMID:8041771 -1.14.11.16 * homo sapiens 86000.0 4 PMID:16564107;PMID:19663697;PMID:25483102;PMID:7821814 -1.14.11.16 * rattus norvegicus 110000.0 2 PMID:19393862 -1.14.11.17 * escherichia coli 127000.0 6 PMID:22221834;PMID:9287300 -1.14.11.17 * pseudomonas putida 121000.0 6 PMID:10913158;PMID:22221834 -1.14.11.18 * homo sapiens 41200.0 3 PMID:16186124;PMID:9326940 -1.14.11.18 * rattus norvegicus 38600.0 3 PMID:10588950;PMID:9326940 -1.14.11.2 * arabidopsis thaliana 35000.0 1 PMID:15528200 -1.14.11.2 * bacillus anthracis 54000.0 1 PMID:18765905 -1.14.11.2 * caenorhabditis elegans 180000.0 3 PMID:18276589;PMID:7929409 -1.14.11.2 * chlamydomonas reinhardtii 250000.0 10 PMID:17220203;PMID:24232556;PMID:28001367;PMID:2851981;PMID:3036064 -1.14.11.2 * dictyostelium discoideum 33350.0 2 PMID:15705570 -1.14.11.2 * gallus gallus 600000.0 8 PMID:1320042;PMID:170085;PMID:3028370;PMID:4346946;PMID:6210830;PMID:6255999 -1.14.11.2 * homo sapiens 640000.0 11 PMID:1320042;PMID:15555944;PMID:16473674;PMID:16509823;PMID:16782814;PMID:170109;PMID:28001367;PMID:2832510;PMID:6210830 -1.14.11.2 * mus musculus 300000.0 2 PMID:4342109 -1.14.11.2 * mytilus edulis 240000.0 1 PMID:170109;PMID:2832510;PMID:6210830 -1.14.11.2 * nicotiana tabacum 33000.0 2 PMID:15610351 -1.14.11.2 * panagrellus silusiae 285000.0 2 * -1.14.11.2 * paramecium bursaria chlorella virus 1 30000.0 2 PMID:10428773 -1.14.11.2 * phaseolus vulgaris 300000.0 2 PMID:2996486 -1.14.11.2 * rattus norvegicus 240000.0 1 PMID:170109;PMID:2832510;PMID:6210830 -1.14.11.2 * streptomyces griseoviridis 37700.0 2 PMID:15528200 -1.14.11.2 * ulva intestinalis 40000.0 1 PMID:2851981;PMID:3036064 -1.14.11.2 * volvox carteri 65000.0 2 PMID:2851981;PMID:3036064 -1.14.11.2 * xenopus laevis 45300.0 2 PMID:17303083 -1.14.11.20 * catharanthus roseus 45647.0 3 PMID:16667836;PMID:8449913;PMID:9290645 -1.14.11.21 * streptomyces antibioticus 41000.0 2 PMID:7890654 -1.14.11.21 * streptomyces clavuligerus 42000.0 6 PMID:2207091;PMID:7876185;PMID:7890654 -1.14.11.24 * hordeum vulgare 37700.0 1 PMID:11117263 -1.14.11.26 * amycolatopsis lactamdurans 34366.0 1 PMID:8703431 -1.14.11.26 * hapsidospora chrysogena 43000.0 5 PMID:3558321;PMID:3663194 -1.14.11.26 * streptomyces clavuligerus 35000.0 2 PMID:2656705;PMID:3997672 -1.14.11.27 * saccharomyces cerevisiae 250000.0 2 PMID:17470555 -1.14.11.28 * streptomyces sp. 35000.0 5 PMID:9294421 -1.14.11.29 * homo sapiens 45651.0 3 PMID:21421125 -1.14.11.3 * neurospora crassa 47000.0 2 PMID:4265566 -1.14.11.3 * rhodotorula glutinis 64600.0 1 PMID:6684117 -1.14.11.35 * streptomyces avermitilis 37139.0 2 PMID:16704250 -1.14.11.38 * aspergillus fumigatus 81000.0 4 PMID:19763315;PMID:21404415 -1.14.11.4 * gallus gallus 550000.0 3 PMID:181088;PMID:5010290;PMID:6779811 -1.14.11.4 * homo sapiens 180000.0 7 PMID:11956192;PMID:18298658;PMID:18834968;PMID:20684070;PMID:7982970;PMID:9054364;PMID:9724729 -1.14.11.4 * mus musculus 97000.0 4 PMID:15619673;PMID:16447251;PMID:16996725 -1.14.11.4 * rattus norvegicus 85000.0 1 PMID:11714250;PMID:7578263 -1.14.11.4 * sus scrofa 115000.0 2 * -1.14.11.4 * takifugu rubripes 85063.0 3 PMID:23954882 -1.14.11.40 * streptomyces hygroscopicus 38600.0 1 PMID:16298295 -1.14.11.41 * streptomyces vinaceus 41600.0 1 PMID:19490124 -1.14.11.43 * delftia acidovorans 32000.0 2 PMID:12501996 -1.14.11.43 * sphingobium herbicidovorans 33700.0 2 PMID:16820480 -1.14.11.44 * delftia acidovorans 108000.0 2 PMID:12501996;PMID:16820480 -1.14.11.44 * sphingobium herbicidovorans 104000.0 3 PMID:12501996;PMID:16820480 -1.14.11.45 * bacillus thuringiensis 31000.0 1 PMID:19850012 -1.14.11.48 * aspergillus nidulans 500000.0 2 PMID:17429948 -1.14.11.48 * aspergillus oryzae 40400.0 1 PMID:33716123 -1.14.11.49 * streptomyces sp. 40000.0 4 PMID:21216959;PMID:23034228 -1.14.11.51 * drosophila melanogaster 300000.0 1 PMID:25936838 -1.14.11.51 * mus musculus 43746.0 1 PMID:27027282 -1.14.11.52 * streptomyces hygroscopicus subsp. limoneus 43400.0 1 PMID:22961651 -1.14.11.53 * homo sapiens 35000.0 2 PMID:24192356 -1.14.11.55 * acidiphilium cryptum 34100.0 1 PMID:24714029 -1.14.11.55 * alkalilimnicola ehrlichii 34300.0 1 PMID:24714029 -1.14.11.55 * halomonas elongata 37400.0 1 PMID:24714029 -1.14.11.55 * nitrosopumilus maritimus 71400.0 1 PMID:26636559 -1.14.11.55 * paenibacillus lautus 34800.0 1 PMID:24714029 -1.14.11.55 * sphingopyxis alaskensis 70730.0 3 PMID:24714029;PMID:25172507 -1.14.11.55 * streptomyces coelicolor 32700.0 1 PMID:18849444 -1.14.11.55 * stutzerimonas stutzeri 34200.0 1 PMID:24714029 -1.14.11.55 * virgibacillus salexigens 36000.0 3 PMID:17636255;PMID:24714029 -1.14.11.57 * dactylosporangium sp. rh1 31000.0 2 PMID:10473412 -1.14.11.57 * streptomyces griseoviridis 38000.0 2 * -1.14.11.6 * rhodotorula glutinis 42700.0 3 PMID:15794921;PMID:6684117 -1.14.11.65 * homo sapiens 300000.0 4 PMID:16603237;PMID:21510664;PMID:24214985 -1.14.11.67 * homo sapiens 192000.0 1 PMID:25190814 -1.14.11.68 * homo sapiens 154177.0 1 PMID:32817139 -1.14.11.68 * mus musculus 154354.0 1 PMID:32817139 -1.14.11.7 * gallus gallus 160000.0 1 PMID:230821 -1.14.11.7 * mus musculus 51530.0 1 PMID:17055431 -1.14.11.72 * leisingera caerulea 70000.0 1 PMID:30789718 -1.14.11.75 * pantoea ananatis 30000.0 1 PMID:23554367 -1.14.11.8 * bos taurus 180000.0 3 PMID:6813145 -1.14.11.8 * rattus norvegicus 87000.0 2 PMID:11431483 -1.14.11.9 * glycine max 68000.0 2 PMID:18414005 -1.14.11.9 * hordeum vulgare 43600.0 1 PMID:8223617 -1.14.11.9 * matthiola incana 40000.0 1 PMID:8223617 -1.14.11.9 * oryza sativa 42700.0 3 PMID:18413994 -1.14.11.9 * petroselinum crispum 48000.0 1 PMID:2221917 -1.14.11.9 * petunia x hybrida 74000.0 4 PMID:10675568;PMID:3699024 -1.14.11.9 * reaumuria songarica 41350.0 1 PMID:24121417 -1.14.11.9 * vitis vinifera 41000.0 1 * -1.14.12.1 * acinetobacter sp. 54000.0 5 PMID:14622009;PMID:9721284 -1.14.12.1 * burkholderia cepacia 48000.0 4 PMID:13129960 -1.14.12.10 * acinetobacter calcoaceticus 52300.0 1 PMID:12732969 -1.14.12.10 * pseudomonas putida 280000.0 15 PMID:12135383;PMID:16470664;PMID:7130163;PMID:7372624 -1.14.12.11 * pseudomonas putida 151000.0 11 PMID:18166197;PMID:2280710;PMID:2982815;PMID:526270;PMID:7204373 -1.14.12.12 * corynebacterium renale 99000.0 3 PMID:7333274 -1.14.12.12 * plasmid nah7 37000.0 1 PMID:1429451 -1.14.12.12 * pseudomonas putida 53000.0 2 PMID:10390817 -1.14.12.12 * pseudomonas sp. 158000.0 7 PMID:2294092;PMID:6874638 -1.14.12.12 * rhodococcus sp. (in: high g+c gram-positive bacteria) 155000.0 3 PMID:10498739 -1.14.12.12 * sphingomonas sp. 200000.0 5 PMID:17014090 -1.14.12.13 * burkholderia cepacia 220000.0 8 PMID:1370284;PMID:7530709 -1.14.12.13 * pseudomonas aeruginosa 13000.0 1 PMID:8195093 -1.14.12.14 * alcaligenes sp. 134000.0 3 * -1.14.12.15 * comamonas sp. 140000.0 9 PMID:16517628;PMID:18776687 -1.14.12.15 * comamonas testosteroni 126000.0 3 PMID:7961417 -1.14.12.15 * delftia tsuruhatensis 235000.0 3 PMID:12670689 -1.14.12.17 * escherichia coli 43000.0 1 PMID:9724711 -1.14.12.17 * mycolicibacterium smegmatis 25000.0 2 PMID:16814781 -1.14.12.18 * comamonas testosteroni 234000.0 5 PMID:8626504 -1.14.12.18 * pseudomonas sp. 209000.0 5 PMID:7592331;PMID:9683647 -1.14.12.18 * sphingobium yanoikuyae 217000.0 3 PMID:17211635 -1.14.12.19 * escherichia coli 51109.0 4 PMID:9603882 -1.14.12.22 * janthinobacterium sp. j3 36000.0 1 PMID:17554172 -1.14.12.22 * metapseudomonas resinovorans 132000.0 5 PMID:12450807 -1.14.12.22 * nocardioides aromaticivorans 124000.0 4 PMID:17142899 -1.14.12.22 * pseudomonas sp. 43000.0 1 PMID:9244274 -1.14.12.22 * sphingomonas sp. 38800.0 1 PMID:20516607 -1.14.12.23 * acidovorax sp. 216000.0 7 PMID:16000792 -1.14.12.24 * burkholderia sp. 187000.0 4 PMID:12743828;PMID:9573183 -1.14.12.3 * pseudomonas putida 215300.0 12 PMID:2280718;PMID:3360142;PMID:3446181;PMID:435241;PMID:6324743;PMID:9056850 -1.14.12.3 * pseudomonas sp. 186000.0 1 PMID:167712 -1.14.12.7 * burkholderia cepacia 290000.0 5 PMID:16922496;PMID:17764654;PMID:2280719;PMID:3805038 -1.14.12.7 * comamonas testosteroni 300000.0 1 PMID:34800435 -1.14.12.8 * comamonas testosteroni 105000.0 7 PMID:2012609;PMID:8828208 -1.14.12.9 * pseudomonas sp. 144000.0 3 PMID:3036855;PMID:3745216 -1.14.13.1 * cutaneotrichosporon cutaneum 45300.0 2 PMID:6539772 -1.14.13.1 * pseudomonas putida 52000.0 4 PMID:11826899;PMID:2363715;PMID:4824919;PMID:7765077 -1.14.13.1 * pseudomonas reinekei 50712.0 2 PMID:17172348 -1.14.13.1 * pseudomonas sp. 57200.0 4 PMID:14321380;PMID:16035243;PMID:16105654;PMID:4401700;PMID:713855 -1.14.13.10 * paenarthrobacter nicotinovorans 113000.0 4 PMID:11514508;PMID:18440023;PMID:4344227 -1.14.13.101 * tyria jacobaeae 200000.0 2 PMID:9182998 -1.14.13.101 * zonocerus variegatus 91200.0 2 PMID:22363737 -1.14.13.105 * rhodococcus erythropolis 60000.0 2 PMID:10769172 -1.14.13.111 * marinosulfonomonas methylotropha 48373.0 4 PMID:11772638 -1.14.13.111 * methylosulfonomonas methylovora 209000.0 11 PMID:10591843;PMID:10903510;PMID:9068643 -1.14.13.113 * klebsiella pneumoniae 45000.0 1 PMID:19260710 -1.14.13.113 * xanthomonas campestris 52519.0 2 PMID:23760935 -1.14.13.114 * pseudomonas fluorescens 42886.0 1 PMID:10091591 -1.14.13.114 * pseudomonas putida 42000.0 1 PMID:18678916 -1.14.13.122 * arabidopsis thaliana 61300.0 4 PMID:15086960;PMID:18846283;PMID:31156665 -1.14.13.122 * micromonas pusilla 40000.0 1 PMID:23677999 -1.14.13.122 * prochlorothrix hollandica 40830.0 1 PMID:14716565 -1.14.13.127 * escherichia coli 669000.0 2 PMID:31811039;PMID:9098055 -1.14.13.128 * pseudomonas putida 240000.0 3 PMID:17009088;PMID:20966097;PMID:22328667 -1.14.13.130 * arthrobacter sp. 160000.0 2 * -1.14.13.130 * rhodococcus sp. (in: high g+c gram-positive bacteria) 150000.0 2 PMID:9395321 -1.14.13.131 * arthrobacter globiformis 39500.0 1 PMID:32391470 -1.14.13.131 * hyphomicrobium sulfonivorans 73000.0 3 PMID:21216999 -1.14.13.135 * alcaligenes sp. 66000.0 2 PMID:20727010 -1.14.13.146 * taxus cuspidata 57146.0 1 PMID:12729625 -1.14.13.148 * calanus finmarchicus 130000.0 1 * -1.14.13.148 * canis lupus familiaris 56000.0 1 PMID:19635782 -1.14.13.148 * homo sapiens 60000.0 2 PMID:19635782;PMID:22177984 -1.14.13.148 * oryctolagus cuniculus 62992.0 2 PMID:8188717 -1.14.13.154 * saccharopolyspora erythraea 43759.0 1 PMID:8416893 -1.14.13.16 * pseudomonas sp. 200000.0 3 PMID:2177830;PMID:4313 -1.14.13.160 * pseudomonas putida 118000.0 8 PMID:22267661;PMID:22286514;PMID:6848481 -1.14.13.161 * salvia officinalis 58000.0 1 PMID:12231778 -1.14.13.163 * agrobacterium tumefaciens 90000.0 1 PMID:25054198 -1.14.13.163 * pseudomonas putida 80000.0 3 PMID:18203859;PMID:21949128 -1.14.13.166 * pseudomonas putida 46600.0 1 PMID:19851007 -1.14.13.166 * pseudomonas sp. 47000.0 1 PMID:19218392 -1.14.13.166 * sphingomonas sp. 59933.0 1 PMID:10220902 -1.14.13.167 * pseudomonas putida 46600.0 1 PMID:19851007 -1.14.13.167 * pseudomonas sp. 47000.0 1 PMID:19218392 -1.14.13.167 * rhodococcus opacus 59700.0 1 PMID:15262926 -1.14.13.168 * arabidopsis thaliana 48000.0 1 PMID:23188833 -1.14.13.170 * streptomyces arenae 66915.0 1 PMID:21250661 -1.14.13.170 * streptomyces exfoliatus 67480.0 1 PMID:21250661 -1.14.13.171 * streptomyces avermitilis 65826.0 2 PMID:19485417 -1.14.13.172 * pseudomonas sp. 48799.0 2 PMID:9573207 -1.14.13.172 * ralstonia sp. 195200.0 5 PMID:23624660 -1.14.13.172 * rhodococcus erythropolis 180000.0 2 * -1.14.13.178 * pseudomonas putida 40200.0 2 PMID:22328667 -1.14.13.179 * pseudomonas putida 40900.0 1 PMID:22328667 -1.14.13.180 * streptomyces peucetius 52000.0 1 PMID:7773378 -1.14.13.180 * streptomyces purpurascens 60000.0 2 PMID:10082933;PMID:7751313 -1.14.13.181 * streptomyces peucetius 46096.0 1 PMID:9864343;PMID:9864344 -1.14.13.181 * streptomyces sp. 47000.0 3 PMID:8655530;PMID:9864343;PMID:9864344 -1.14.13.182 * pseudomonas aeruginosa 86000.0 1 PMID:20662781 -1.14.13.195 * pseudomonas aeruginosa 136600.0 2 PMID:17015659 -1.14.13.196 * aspergillus fumigatus 228000.0 3 PMID:20614882 -1.14.13.2 * acinetobacter calcoaceticus 89000.0 1 PMID:7490269 -1.14.13.2 * comamonas testosteroni 71000.0 1 * -1.14.13.2 * corynebacterium glutamicum 80000.0 2 PMID:18071645;PMID:2513888 -1.14.13.2 * klebsiella pneumoniae 80000.0 2 PMID:7646318 -1.14.13.2 * moraxella sp. 85000.0 2 PMID:18071645;PMID:2513888 -1.14.13.2 * pseudomonas aeruginosa 75000.0 3 PMID:18071645;PMID:2177819;PMID:2513888 -1.14.13.2 * pseudomonas fluorescens 90000.0 5 PMID:116851;PMID:30879;PMID:4380381;PMID:4402514 -1.14.13.2 * pseudomonas putida 44000.0 1 PMID:11390692 -1.14.13.2 * pseudomonas sp. 90000.0 3 PMID:8706756 -1.14.13.2 * rhodococcus opacus 51000.0 3 PMID:11566060 -1.14.13.2 * rhodococcus rhodnii 48500.0 1 PMID:11566060 -1.14.13.2 * rhodococcus rhodochrous 45000.0 1 PMID:11566060 -1.14.13.2 * rhodococcus sp. (in: high g+c gram-positive bacteria) 45000.0 1 PMID:11566060 -1.14.13.20 * acinetobacter sp. 240000.0 2 PMID:7075592 -1.14.13.20 * burkholderia cepacia 275000.0 2 PMID:1898014 -1.14.13.20 * cupriavidus necator 245000.0 5 PMID:6745439;PMID:9090109 -1.14.13.20 * pseudomonadota 256000.0 2 PMID:9418244 -1.14.13.200 * streptomyces glaucescens 61000.0 2 PMID:7982994 -1.14.13.200 * streptomyces olivaceus 58085.0 2 PMID:11325225 -1.14.13.208 * aromatoleum evansii 98000.0 6 PMID:11222587;PMID:12399500;PMID:15458418;PMID:20452977 -1.14.13.209 * streptomyces sp. 56600.0 1 PMID:15006746 -1.14.13.210 * burkholderia sp. 65000.0 2 PMID:8830701 -1.14.13.212 * pseudomonas sp. 43000.0 1 PMID:25678373 -1.14.13.217 * chromobacterium violaceum 42000.0 1 PMID:17176066 -1.14.13.218 * pseudomonas aeruginosa 43600.0 2 PMID:11591691;PMID:17012792 -1.14.13.22 * acinetobacter calcoaceticus 60000.0 1 * -1.14.13.22 * acinetobacter sp. 61670.0 6 PMID:11162390;PMID:1261545;PMID:14597129;PMID:7093214 -1.14.13.22 * exophiala jeanselmei 74000.0 1 PMID:11210139 -1.14.13.22 * ilyonectria destructans 76000.0 3 PMID:22075635 -1.14.13.22 * nocardia globerula 53000.0 1 PMID:1261545 -1.14.13.22 * xanthobacter sp. 51000.0 2 PMID:2540966 -1.14.13.220 * rhodococcus jostii 59000.0 1 PMID:26319878 -1.14.13.222 * stigmatella aurantiaca 41290.0 1 PMID:22907798 -1.14.13.223 * streptosporangium sibiricum 39900.0 1 PMID:21612226 -1.14.13.224 * chromobacterium violaceum 48000.0 1 PMID:17176066 -1.14.13.225 * homo sapiens 79400.0 1 PMID:31949908 -1.14.13.226 * gordonia sp. ty-5 230000.0 2 PMID:17071761 -1.14.13.229 * aquincola tertiaricarbonis 55000.0 1 * -1.14.13.23 * comamonas testosteroni 145000.0 2 PMID:4148586 -1.14.13.231 * bacteroides fragilis 44000.0 2 PMID:15452119;PMID:1846135 -1.14.13.234 * kitasatospora aureofaciens 115000.0 2 PMID:3138982 -1.14.13.236 * ectopseudomonas mendocina 220000.0 6 PMID:1429451;PMID:8703915 -1.14.13.239 * acinetobacter baumannii 139000.0 1 PMID:32694223 -1.14.13.24 * aquipseudomonas alcaligenes 130000.0 2 PMID:16267294 -1.14.13.24 * burkholderia cepacia 45000.0 2 PMID:3567157 -1.14.13.24 * candida parapsilosis 49900.0 1 PMID:21474535 -1.14.13.24 * corynebacterium glutamicum 125000.0 2 PMID:20806251 -1.14.13.24 * klebsiella oxytoca 44000.0 1 PMID:15782938 -1.14.13.24 * klebsiella pneumoniae 42000.0 2 PMID:7729672 -1.14.13.24 * micrococcus sp. 70000.0 2 PMID:2321959 -1.14.13.24 * polaromonas naphthalenivorans 43000.0 1 PMID:17586666 -1.14.13.24 * pseudomonas aeruginosa 85000.0 1 PMID:4357436 -1.14.13.24 * rhodococcus jostii 108000.0 3 PMID:22207056;PMID:22559817 -1.14.13.24 * rhodococcus sp. (in: high g+c gram-positive bacteria) 119000.0 2 PMID:21181154 -1.14.13.241 * arthrobacter sp. 51000.0 3 PMID:3771566 -1.14.13.241 * pseudomonas sp. 166000.0 2 PMID:3771566;PMID:4306031 -1.14.13.242 * mesorhizobium loti 164000.0 1 PMID:17270714 -1.14.13.242 * pseudomonas sp. 166000.0 4 PMID:4306031;PMID:7217081;PMID:9207074 -1.14.13.244 * rhodococcus erythropolis 238000.0 3 PMID:19787347 -1.14.13.25 * methylobacterium sp. 220000.0 4 PMID:3106336 -1.14.13.25 * methylococcus capsulatus 251000.0 12 PMID:10381404;PMID:11709550;PMID:27033202;PMID:27878395;PMID:418777;PMID:6323414;PMID:9310362 -1.14.13.25 * methylocystis sp. 229000.0 8 PMID:10473397 -1.14.13.25 * methylosinus sporium 220000.0 4 PMID:3106336 -1.14.13.25 * methylosinus trichosporium 246000.0 21 PMID:15544;PMID:17213640;PMID:18540635;PMID:2280705;PMID:2542319;PMID:2840063;PMID:34100595 -1.14.13.251 * chromohalobacter israelensis 154800.0 2 PMID:29703733 -1.14.13.252 * acinetobacter baumannii 248000.0 1 PMID:36314559 -1.14.13.27 * agaricus bisporus 50950.0 3 PMID:3489713;PMID:8950172 -1.14.13.29 * homo sapiens 40000.0 1 PMID:8267647 -1.14.13.29 * rhodococcus sp. pn1 207000.0 3 PMID:18805976 -1.14.13.31 * pseudomonas putida 65000.0 2 PMID:3350791 -1.14.13.32 * rattus norvegicus 59000.0 1 PMID:7736906 -1.14.13.33 * paenibacillus sp. 41000.0 1 PMID:19717587 -1.14.13.33 * sinomonas cyclohexanicum 47000.0 1 PMID:3971979 -1.14.13.35 * aspergillus niger 89000.0 2 PMID:6501219 -1.14.13.35 * cutaneotrichosporon cutaneum 95000.0 2 PMID:3793735 -1.14.13.38 * kitasatospora aureofaciens 115000.0 2 PMID:3136241;PMID:3138982 -1.14.13.39 * aplysia californica 160000.0 1 PMID:15811509;PMID:1702732 -1.14.13.39 * bacillus anthracis 43000.0 1 PMID:16150307 -1.14.13.39 * bos taurus 320000.0 6 PMID:1371919;PMID:1379040;PMID:1379222;PMID:1689048;PMID:1712021;PMID:1722402;PMID:9875419 -1.14.13.39 * drosophila melanogaster 152000.0 1 PMID:12804606 -1.14.13.39 * homo sapiens 160000.0 9 PMID:1377649;PMID:1722402;PMID:17636472;PMID:18675932;PMID:7515853;PMID:9748253;PMID:9875419 -1.14.13.39 * mus musculus 260000.0 9 PMID:16461329;PMID:1715579;PMID:1720773;PMID:17443799;PMID:7530045;PMID:7545434;PMID:7691806;PMID:8631749 -1.14.13.39 * nicotiana tabacum 120000.0 2 PMID:12757708 -1.14.13.39 * oreochromis mossambicus x niloticus 178000.0 3 PMID:18201058 -1.14.13.39 * rattus norvegicus 300000.0 7 PMID:1371919;PMID:1379222;PMID:16461329;PMID:1689048;PMID:1704888;PMID:1712021;PMID:7515853 -1.14.13.39 * staphylococcus aureus 135000.0 3 PMID:12770704 -1.14.13.39 * sus scrofa 200000.0 2 PMID:15811509;PMID:1702732 -1.14.13.39 * triatoma infestans 134000.0 1 PMID:17235602 -1.14.13.4 * arthrobacter sp. 65000.0 1 PMID:6017743 -1.14.13.4 * pseudomonas sp. 250000.0 2 PMID:4348920 -1.14.13.40 * aromatoleum evansii 165000.0 2 PMID:11514509;PMID:25843773 -1.14.13.40 * pseudomonas sp. 170000.0 2 PMID:2591379 -1.14.13.44 * pseudomonas nitroreducens 256000.0 2 PMID:9305879 -1.14.13.5 * pseudomonas sp. 90000.0 1 PMID:5665242;PMID:5772468 -1.14.13.50 * flavobacterium sp. 66000.0 2 PMID:2066340 -1.14.13.50 * pseudomonas fluorescens 24000.0 1 PMID:12783196 -1.14.13.50 * pseudomonas sp. 30000.0 1 PMID:11785966 -1.14.13.50 * sphingobium chlorophenolicum 60000.0 1 PMID:14600375 -1.14.13.50 * sphingomonas sp. 59930.0 1 PMID:10220902 -1.14.13.54 * ilyonectria destructans 116000.0 2 PMID:3486863 -1.14.13.54 * rhodococcus rhodochrous 60919.0 3 PMID:10467180 -1.14.13.58 * pseudomonas sp. 65000.0 2 PMID:7851381 -1.14.13.59 * escherichia coli 200000.0 2 PMID:2518519 -1.14.13.6 * pseudomonas putida 70000.0 7 PMID:1126936;PMID:11945483;PMID:1280 -1.14.13.61 * pseudomonas putida 330000.0 6 PMID:7629085;PMID:9171399 -1.14.13.62 * pseudomonas putida 126000.0 2 PMID:1627263 -1.14.13.63 * flavobacterium sp. 200000.0 2 PMID:1935954 -1.14.13.63 * rhodococcus erythropolis 50000.0 2 * -1.14.13.64 * candida parapsilosis 52600.0 4 PMID:21474535;PMID:9352916 -1.14.13.69 * nocardioides sp. js614 58000.0 1 PMID:20121086 -1.14.13.69 * xanthobacter autotrophicus 58100.0 3 PMID:15476981 -1.14.13.69 * xanthobacter sp. 58037.0 5 PMID:10103255 -1.14.13.7 * acinetobacter radioresistens 207000.0 6 PMID:10504385;PMID:12752444 -1.14.13.7 * candida tropicalis 320000.0 1 PMID:25140701 -1.14.13.7 * comamonas testosteroni 240000.0 2 PMID:22167219 -1.14.13.7 * corynebacterium glutamicum 140000.0 1 PMID:26377129 -1.14.13.7 * cutaneotrichosporon cutaneum 302000.0 5 PMID:4146224;PMID:7858421;PMID:810352 -1.14.13.7 * pseudomonas sp. 25500.0 1 PMID:20920460 -1.14.13.8 * carcharhinus falciformis 50000.0 1 PMID:7881827 -1.14.13.8 * cavia porcellus 58000.0 3 PMID:2369122;PMID:7872795 -1.14.13.8 * homo sapiens 104000.0 6 PMID:20810540;PMID:7872795 -1.14.13.8 * macaca fascicularis 65000.0 2 PMID:23623750;PMID:8448176 -1.14.13.8 * methylophaga aminisulfidivorans 53000.0 1 PMID:18443301 -1.14.13.8 * methylophaga sp. 54000.0 1 PMID:21225061 -1.14.13.8 * mus musculus 59000.0 1 PMID:3919719 -1.14.13.8 * oryctolagus cuniculus 60000.0 2 PMID:1911780;PMID:3919719 -1.14.13.8 * rattus norvegicus 60000.0 3 PMID:11414682;PMID:18775983;PMID:8787783 -1.14.13.8 * scophthalmus maximus 55000.0 1 PMID:7618340 -1.14.13.8 * squalus acanthias 50000.0 1 PMID:7881827 -1.14.13.8 * sus scrofa 65000.0 5 PMID:2322534;PMID:36396;PMID:672624;PMID:7947951 -1.14.13.81 * chloroflexus aurantiacus 45000.0 2 PMID:19346304 -1.14.13.81 * cucumis sativus 30000.0 2 * -1.14.13.81 * ipomoea nil 43000.0 1 * -1.14.13.81 * rubrivivax gelatinosus 210000.0 1 PMID:33731920 -1.14.13.82 * acinetobacter baylyi 43000.0 1 PMID:21221570 -1.14.13.83 * brucella melitensis 50000.0 1 PMID:19068481 -1.14.13.83 * pseudomonas denitrificans (nom. rej.) 50000.0 6 PMID:19068481;PMID:7606163;PMID:8405386;PMID:9224567 -1.14.13.84 * pseudomonas fluorescens 145200.0 6 PMID:11322873;PMID:15153101;PMID:16049018;PMID:18502868 -1.14.13.84 * pseudomonas putida 71000.0 2 PMID:11073896 -1.14.13.9 * aedes aegypti 54000.0 1 PMID:12974953 -1.14.13.9 * anopheles stephensi 60000.0 1 PMID:12230548 -1.14.13.9 * homo sapiens 62136.0 3 PMID:10672018;PMID:29208702;PMID:9237672 -1.14.13.9 * pseudomonas fluorescens 50000.0 1 PMID:16973376 -1.14.13.9 * rattus norvegicus 345000.0 5 PMID:10672018;PMID:1225915;PMID:893360;PMID:9237672 -1.14.13.9 * sus scrofa 49000.0 1 PMID:10721109 -1.14.13.92 * thermobifida fusca 65000.0 1 PMID:15599520 -1.14.14.1 * aspergillus terreus 110000.0 1 PMID:17251009 -1.14.14.1 * bacillus licheniformis 120000.0 1 PMID:18483737 -1.14.14.1 * claviceps purpurea 58200.0 1 PMID:16538694 -1.14.14.1 * homo sapiens 52000.0 1 PMID:15853388 -1.14.14.1 * neogale vison 58500.0 2 PMID:19041884 -1.14.14.1 * rhodococcus ruber 89000.0 1 PMID:16607529 -1.14.14.1 * rhodococcus sp. (in: high g+c gram-positive bacteria) 87190.0 1 PMID:19633839 -1.14.14.1 * thermobifida fusca 48000.0 1 PMID:21057946 -1.14.14.10 * aminobacter aminovorans 50500.0 3 PMID:1735711;PMID:8892809;PMID:9023192 -1.14.14.10 * chelativorans sp. bnc1 45000.0 1 PMID:9683478 -1.14.14.10 * corynebacterium glutamicum 100000.0 2 PMID:17077499 -1.14.14.102 * coptis chinensis 55040.0 1 * -1.14.14.103 * catharanthus roseus 129000.0 1 PMID:10481044 -1.14.14.105 * taxus x media 57000.0 1 * -1.14.14.108 * pseudomonas putida 120000.0 15 PMID:23524667;PMID:3944058;PMID:4286778;PMID:4310834;PMID:8515237;PMID:8674690 -1.14.14.11 * marinobacterium litorale 66000.0 1 PMID:33802034 -1.14.14.11 * pseudomonas putida 45000.0 2 PMID:30678678 -1.14.14.11 * pseudomonas sp. 80000.0 3 PMID:15292130;PMID:20675468 -1.14.14.11 * rhodococcus opacus 80000.0 2 PMID:15292130;PMID:20675468 -1.14.14.11 * rhodococcus sp. (in: high g+c gram-positive bacteria) 59000.0 6 PMID:21996027;PMID:22258641 -1.14.14.114 * artemisia annua 53800.0 1 * -1.14.14.116 * aspergillus parasiticus 56300.0 2 PMID:9097431 -1.14.14.117 * aspergillus parasiticus 60000.0 1 PMID:11996570 -1.14.14.120 * panax quinquefolius 60000.0 1 PMID:23502156 -1.14.14.121 * panax ginseng 55300.0 1 PMID:22875608 -1.14.14.126 * medicago truncatula 57000.0 1 PMID:21821776 -1.14.14.126 * panax ginseng 54000.0 2 PMID:24092881 -1.14.14.127 * diploptera punctata 55000.0 2 PMID:15024118;PMID:7627203 -1.14.14.13 * niallia circulans 40000.0 2 PMID:15975512 -1.14.14.133 * citrobacter braakii 45000.0 1 PMID:12016226 -1.14.14.137 * arabidopsis thaliana 53000.0 2 PMID:15064374 -1.14.14.139 * oryctolagus cuniculus 56000.0 2 PMID:1400444;PMID:6806291 -1.14.14.14 * homo sapiens 55000.0 1 PMID:3104339 -1.14.14.141 * ammi majus 55891.0 1 PMID:17068340 -1.14.14.143 * mentha pulegium 55360.0 1 PMID:11396930 -1.14.14.15 * streptomyces globisporus 63200.0 1 PMID:18426211 -1.14.14.154 * bos taurus 50000.0 1 PMID:14630712 -1.14.14.154 * candida albicans 100000.0 3 PMID:21315684;PMID:21698128;PMID:30126961 -1.14.14.154 * leishmania infantum 54000.0 1 PMID:21632531 -1.14.14.154 * mus musculus 53000.0 1 PMID:14630712 -1.14.14.154 * nakaseomyces glabratus 100000.0 1 PMID:30126961 -1.14.14.154 * ovis aries 50000.0 1 PMID:14630712 -1.14.14.154 * penicillium digitatum 59000.0 1 PMID:17986082 -1.14.14.154 * penicillium italicum 57300.0 1 PMID:8628233 -1.14.14.154 * phanerodontia chrysosporium 63000.0 2 PMID:18853217 -1.14.14.154 * pneumocystis carinii 59000.0 1 PMID:12606318 -1.14.14.154 * pyricularia grisea 51000.0 1 PMID:19152375 -1.14.14.154 * rattus norvegicus 55050.0 1 PMID:7665087 -1.14.14.154 * solanum chacoense 55200.0 1 PMID:16169959 -1.14.14.154 * sorghum bicolor 53000.0 1 PMID:8955137 -1.14.14.154 * taiwanofungus camphoratus 87900.0 3 PMID:20334412 -1.14.14.154 * trypanosoma cruzi 52000.0 1 PMID:14599667 -1.14.14.155 * pseudomonas putida 85000.0 8 PMID:22286514;PMID:23524667;PMID:8515237;PMID:8674690 -1.14.14.156 * arabidopsis thaliana 61000.0 2 PMID:10922360 -1.14.14.16 * bos taurus 167000.0 8 PMID:16597434;PMID:3931675;PMID:6767716;PMID:6972231;PMID:7130172 -1.14.14.16 * homo sapiens 50000.0 1 PMID:25855791 -1.14.14.16 * sus scrofa 54000.0 2 PMID:3495238;PMID:6830757 -1.14.14.17 * candida albicans 55300.0 1 PMID:15845783 -1.14.14.17 * mus musculus 64000.0 1 PMID:17374357 -1.14.14.17 * panax ginseng 60200.0 2 PMID:19857882 -1.14.14.17 * panax notoginseng 59140.0 1 PMID:17852349 -1.14.14.17 * rattus norvegicus 64000.0 4 PMID:12467639;PMID:6776955;PMID:6817796 -1.14.14.17 * sus scrofa 64000.0 1 PMID:12467639 -1.14.14.17 * taraxacum kok-saghyz 68107.0 4 PMID:31245726 -1.14.14.17 * tripterygium wilfordii 57590.0 5 PMID:30125629 -1.14.14.173 * cupriavidus sp. gp1 240000.0 1 PMID:8981999 -1.14.14.178 * solanum lycopersicum 56000.0 2 PMID:16960392 -1.14.14.18 * arabidopsis thaliana 27000.0 1 PMID:19860740 -1.14.14.18 * bos taurus 31000.0 1 PMID:6806282 -1.14.14.18 * clostridium tetani 25000.0 1 PMID:15340779 -1.14.14.18 * corynebacterium diphtheriae 25000.0 2 PMID:10409691;PMID:9422739 -1.14.14.18 * gallus gallus 33000.0 1 PMID:2158889;PMID:438202 -1.14.14.18 * glycine max 26000.0 2 PMID:17076701 -1.14.14.18 * homo sapiens 36500.0 6 PMID:15285018;PMID:17160582;PMID:23097500;PMID:3202858;PMID:7890772 -1.14.14.18 * mus musculus 28000.0 1 PMID:25107906 -1.14.14.18 * neisseria meningitidis 23450.0 1 PMID:16548515 -1.14.14.18 * oryctolagus cuniculus 42000.0 3 PMID:2910857 -1.14.14.18 * rattus norvegicus 200000.0 8 PMID:17253780;PMID:18154739;PMID:18477;PMID:2158889;PMID:2910857;PMID:3525562;PMID:438202;PMID:672640;PMID:96115 -1.14.14.18 * sus scrofa 200000.0 3 PMID:18154739;PMID:438202;PMID:672640;PMID:96115 -1.14.14.19 * danio rerio 54000.0 2 PMID:25533464 -1.14.14.19 * homo sapiens 57000.0 1 PMID:18645707;PMID:3264499 -1.14.14.19 * rattus norvegicus 57000.0 1 PMID:18645707;PMID:3264499 -1.14.14.19 * sus scrofa 59000.0 4 PMID:6404268;PMID:6608525;PMID:6971291;PMID:8240357 -1.14.14.197 * priestia megaterium 47500.0 1 PMID:22532270 -1.14.14.20 * auxenochlorella pyrenoidosa 25000.0 1 PMID:28662620 -1.14.14.20 * geobacillus stearothermophilus 44200.0 2 PMID:19014555 -1.14.14.20 * parageobacillus thermoglucosidasius 57000.0 8 PMID:11054550;PMID:12968028;PMID:23561120 -1.14.14.20 * rhodococcus erythropolis 238000.0 17 PMID:19787347 -1.14.14.20 * rhodococcus opacus 310000.0 1 PMID:25283988 -1.14.14.21 * bacillus subtilis 200000.0 2 PMID:12382053;PMID:16243275 -1.14.14.21 * mycolicibacterium goodii 45000.0 1 * -1.14.14.21 * paenibacillus sp. 200000.0 3 PMID:10733908;PMID:12382053;PMID:16243275 -1.14.14.21 * rhodococcus erythropolis 250000.0 4 PMID:11105249;PMID:9634856 -1.14.14.21 * rhodococcus sp. (in: high g+c gram-positive bacteria) 294000.0 4 PMID:17581702;PMID:8824615 -1.14.14.22 * bacillus subtilis 174000.0 2 PMID:16243275 -1.14.14.22 * paenibacillus sp. 120000.0 3 PMID:10733908;PMID:16232919 -1.14.14.22 * rhodococcus erythropolis 100000.0 4 PMID:11105249;PMID:16232672;PMID:9634856 -1.14.14.23 * homo sapiens 58000.0 3 PMID:12361728;PMID:12943743;PMID:15752749;PMID:8938182 -1.14.14.23 * oryctolagus cuniculus 58000.0 1 PMID:12361728;PMID:12943743 -1.14.14.23 * rattus norvegicus 58000.0 4 PMID:12361728;PMID:12943743;PMID:2154492;PMID:3584134;PMID:8938182 -1.14.14.24 * pseudonocardia autotrophica 44368.0 1 PMID:19450562 -1.14.14.24 * rattus norvegicus 52500.0 1 PMID:2844763;PMID:7498517 -1.14.14.24 * shouchella lehensis 62000.0 1 PMID:29508210 -1.14.14.24 * sus scrofa 56374.0 3 PMID:2844763;PMID:7498517;PMID:9425298 -1.14.14.25 * homo sapiens 56842.0 3 PMID:11111082;PMID:15234274 -1.14.14.25 * mus musculus 56821.0 2 PMID:11111082;PMID:19489738 -1.14.14.26 * bos taurus 44000.0 1 PMID:12649335 -1.14.14.27 * pseudomonas putida 70000.0 2 PMID:1280 -1.14.14.27 * rhizobium sp. mtp-10005 45500.0 1 PMID:17158677 -1.14.14.28 * geobacillus thermodenitrificans 105000.0 2 PMID:18164311 -1.14.14.29 * homo sapiens 58255.0 1 PMID:12543708 -1.14.14.29 * mus musculus 58255.0 1 PMID:12543708 -1.14.14.3 * photobacterium phosphoreum 84000.0 1 PMID:4770374 -1.14.14.3 * photorhabdus luminescens 78000.0 3 PMID:1995589;PMID:2204626 -1.14.14.3 * vibrio campbellii 158000.0 3 PMID:23000378 -1.14.14.3 * vibrio harveyi 78000.0 5 PMID:11900533;PMID:2671993;PMID:3514602;PMID:3997817;PMID:6971121 -1.14.14.30 * streptomyces viridifaciens 126000.0 4 PMID:8990292;PMID:9056232 -1.14.14.31 * ips confusus 65000.0 2 PMID:19034575;PMID:23376633 -1.14.14.31 * ips pini 61000.0 3 PMID:17046597;PMID:19034575;PMID:23376633 -1.14.14.32 * mus musculus 54000.0 1 PMID:19500726 -1.14.14.32 * rattus norvegicus 58000.0 1 PMID:21388459 -1.14.14.32 * spermophilus dauricus 57000.0 1 PMID:20197644 -1.14.14.33 * edta-degrading bacterium bnc1 45000.0 1 PMID:9683478 -1.14.14.34 * pseudomonas aeruginosa 41600.0 1 PMID:10049377 -1.14.14.35 * pseudomonas fluorescens 40000.0 1 PMID:27392454 -1.14.14.36 * sorghum bicolor 61890.0 5 PMID:7487064;PMID:7574710;PMID:7937883 -1.14.14.37 * sorghum bicolor 55000.0 1 PMID:9414567 -1.14.14.38 * manihot esculenta 62000.0 2 PMID:10636899 -1.14.14.39 * manihot esculenta 62000.0 2 PMID:10636899 -1.14.14.40 * arabidopsis thaliana 60000.0 1 PMID:10799553 -1.14.14.42 * arabidopsis thaliana 62000.0 1 PMID:12609033 -1.14.14.42 * brassica oleracea var. alboglabra 61000.0 1 PMID:26569208 -1.14.14.46 * bacillus subtilis 45348.0 3 PMID:11368323;PMID:15449931 -1.14.14.47 * geobacillus kaustophilus 86000.0 1 PMID:16407211 -1.14.14.5 * escherichia coli 181000.0 3 PMID:10480865;PMID:15882995 -1.14.14.51 * mentha spicata 57000.0 2 PMID:10415126;PMID:10864450 -1.14.14.52 * mycobacterium sp. 48000.0 1 PMID:15811996 -1.14.14.53 * mentha canadensis 55858.0 1 * -1.14.14.57 * sus scrofa 53000.0 1 PMID:7649186 -1.14.14.78 * homo sapiens 50000.0 1 PMID:19932081 -1.14.14.78 * mus musculus 58000.0 1 PMID:22665481 -1.14.14.79 * homo sapiens 62163.0 2 PMID:22772592 -1.14.14.80 * homo sapiens 59347.0 3 PMID:19661213;PMID:7798189 -1.14.14.81 * brunfelsia brasiliensis subsp. macrocalyx 56470.0 1 PMID:34356102 -1.14.14.81 * ribes nigrum 57110.0 1 * -1.14.14.81 * taxus chinensis 57752.0 2 PMID:31795268 -1.14.14.82 * brassica napus 56620.0 1 PMID:16618519 -1.14.14.82 * ipomoea batatas 57360.0 1 PMID:21603861 -1.14.14.82 * oenanthe javanica 58293.0 1 * -1.14.14.82 * perilla frutescens 57500.0 1 PMID:11773526 -1.14.14.83 * catharanthus roseus 56300.0 2 PMID:11718718 -1.14.14.83 * swertia mussotii 55500.0 2 PMID:20699579 -1.14.14.84 * pseudomonas putida 45000.0 3 PMID:2295633 -1.14.14.86 * fusarium fujikuroi 55000.0 1 PMID:1397591 -1.14.14.86 * momordica charantia 58800.0 1 * -1.14.14.86 * oryza sativa 70000.0 1 PMID:19060383 -1.14.14.86 * physcomitrium patens 62000.0 1 PMID:21545802 -1.14.14.86 * scoparia dulcis 58300.0 2 PMID:29340903 -1.14.14.87 * lathyrus oleraceus 59400.0 1 * -1.14.14.9 * acinetobacter baumannii 209000.0 8 PMID:11683878;PMID:15451173 -1.14.14.9 * escherichia coli 120000.0 6 PMID:11683878;PMID:8077235;PMID:8458860 -1.14.14.9 * geobacillus sp. 56269.0 2 PMID:17805928 -1.14.14.9 * klebsiella pneumoniae 58781.0 2 PMID:10633095;PMID:9042756 -1.14.14.9 * pseudomonas putida 91000.0 5 PMID:11683878;PMID:3401220 -1.14.14.91 * brassica napus 57730.0 2 PMID:17394776 -1.14.14.91 * glycine max 58000.0 1 PMID:1731635 -1.14.14.91 * gossypium hirsutum 58200.0 2 * -1.14.14.91 * helianthus annuus 57940.0 3 PMID:32683078 -1.14.14.91 * helianthus tuberosus 57000.0 1 PMID:1898022;PMID:8323300 -1.14.14.91 * ipomoea batatas 58150.0 1 * -1.14.14.91 * lycoris aurea 58190.0 1 PMID:30513965 -1.14.14.91 * marchantia paleacea 59600.0 2 PMID:28587992 -1.14.14.91 * ornithogalum saundersiae 57800.0 1 PMID:24476601;PMID:33392729 -1.14.14.91 * phaseolus vulgaris 57000.0 1 PMID:1898022;PMID:8323300 -1.14.14.91 * plagiochasma appendiculatum 61050.0 1 PMID:28587992 -1.14.14.91 * prunus armeniaca 57800.0 1 * -1.14.14.91 * pyrus x bretschneideri 57690.0 4 PMID:32937268 -1.14.14.91 * rehmannia glutinosa 57800.0 1 PMID:24476601;PMID:33392729 -1.14.14.92 * cytospora rhizophorae 60000.0 1 PMID:34807300 -1.14.14.92 * phanerodontia chrysosporium 60000.0 1 PMID:16039998 -1.14.14.92 * pseudomonas sp. 120000.0 1 PMID:13716 -1.14.14.93 * glycine max 55000.0 1 PMID:1731635;PMID:2505672 -1.14.14.94 * homo sapiens 61000.0 3 PMID:10409674;PMID:10833273;PMID:9675028 -1.14.14.94 * mus musculus 59800.0 1 PMID:11185557 -1.14.14.95 * barnadesia spinosa 54900.0 1 PMID:20351109 -1.14.14.95 * cichorium intybus 54900.0 1 PMID:20351109 -1.14.14.95 * dolomiaea costus 54900.0 1 PMID:20351109 -1.14.14.95 * helianthus annuus 54900.0 1 PMID:20351109 -1.14.14.95 * lactuca sativa 54900.0 1 PMID:20351109 -1.14.15.1 * pseudomonas putida 47000.0 3 PMID:18359283;PMID:19458919;PMID:21265500 -1.14.15.10 * rhodococcus sp. (in: high g+c gram-positive bacteria) 44000.0 1 PMID:12172608 -1.14.15.13 * aspergillus parasiticus 56300.0 1 PMID:10855719 -1.14.15.14 * mycobacterium tuberculosis 50000.0 2 PMID:19933331 -1.14.15.15 * oryctolagus cuniculus 56657.0 3 PMID:10512735;PMID:2722778 -1.14.15.15 * rattus norvegicus 52500.0 1 PMID:2253771;PMID:2848026 -1.14.15.16 * homo sapiens 55000.0 3 PMID:21058632;PMID:24893882;PMID:8679605 -1.14.15.16 * mus musculus 59500.0 2 PMID:9165006 -1.14.15.16 * rattus norvegicus 55000.0 1 PMID:23165146 -1.14.15.17 * triticum aestivum 58300.0 1 * -1.14.15.18 * bos taurus 49000.0 1 PMID:6807301 -1.14.15.18 * gallus gallus 53000.0 3 PMID:219848;PMID:6767897;PMID:819434 -1.14.15.18 * homo sapiens 56000.0 1 PMID:15223133 -1.14.15.18 * mus musculus 55000.0 2 PMID:11686044;PMID:9295274 -1.14.15.18 * oryctolagus cuniculus 52000.0 2 PMID:10512735 -1.14.15.18 * pseudonocardia autotrophica 45400.0 1 PMID:19342783 -1.14.15.18 * rattus norvegicus 55000.0 1 PMID:9426217 -1.14.15.18 * sus scrofa 56370.0 1 PMID:11880238 -1.14.15.19 * sorangium cellulosum 50220.0 1 PMID:26478560 -1.14.15.20 * arabidopsis thaliana 53000.0 2 PMID:12481078 -1.14.15.20 * glycine max 26100.0 2 PMID:17076701 -1.14.15.20 * synechocystis sp. 29000.0 2 PMID:15691334 -1.14.15.20 * synechocystis sp. pcc 6803 31000.0 1 PMID:9744099 -1.14.15.21 * gossypium arboreum 73421.0 1 * -1.14.15.21 * medicago sativa 72970.0 1 PMID:26573680 -1.14.15.21 * solanum lycopersicum 73000.0 1 PMID:18275469 -1.14.15.21 * solanum tuberosum 73100.0 1 PMID:16897484 -1.14.15.24 * adonis aestivalis 35000.0 1 PMID:17171373 -1.14.15.24 * arabidopsis thaliana 34400.0 1 PMID:8798688 -1.14.15.24 * capsicum annuum 26000.0 1 PMID:9555077 -1.14.15.24 * citrus unshiu 34000.0 2 * -1.14.15.24 * diospyros kaki 34280.0 1 * -1.14.15.24 * haematococcus lacustris 32720.0 1 * -1.14.15.24 * oryza sativa 64000.0 2 PMID:20852032;PMID:22786888 -1.14.15.24 * pantoea agglomerans 22000.0 1 PMID:8422926 -1.14.15.24 * phaffia rhodozyma 62630.0 2 PMID:16416328;PMID:16455271 -1.14.15.24 * thermus thermophilus 47000.0 1 PMID:16297864 -1.14.15.25 * pseudomonas chlororaphis subsp. aureofaciens 39000.0 1 * -1.14.15.29 * mycobacterium tuberculosis 46400.0 1 PMID:19846551 -1.14.15.29 * mycobacterium tuberculosis variant bovis 48200.0 1 PMID:19846551 -1.14.15.29 * mycolicibacterium neoaurum 46000.0 1 PMID:30073539 -1.14.15.29 * rhodococcus jostii 47200.0 1 PMID:19843222 -1.14.15.3 * alcanivorax borkumensis 150000.0 1 PMID:23337786 -1.14.15.3 * candida maltosa 61800.0 4 PMID:8645001 -1.14.15.3 * drosophila melanogaster 58000.0 1 PMID:18716335 -1.14.15.3 * ectopseudomonas oleovorans 2000000.0 3 PMID:4395379;PMID:4830742;PMID:921275 -1.14.15.3 * fusarium oxysporum 118000.0 1 PMID:8830036 -1.14.15.3 * homo sapiens 52000.0 1 PMID:18203846 -1.14.15.3 * lodderomyces elongisporus 79000.0 1 PMID:6810895 -1.14.15.3 * oryctolagus cuniculus 53000.0 1 PMID:9126328 -1.14.15.3 * pseudomonas aeruginosa 800000.0 1 * -1.14.15.3 * pseudomonas putida 46000.0 1 PMID:22941083 -1.14.15.3 * pusillimonas sp. t7-7 160000.0 2 PMID:23417490 -1.14.15.30 * mycobacterium sp. 45000.0 1 PMID:20352983 -1.14.15.30 * mycolicibacterium neoaurum 45370.0 1 PMID:20204712 -1.14.15.35 * saccharopolyspora erythraea 44000.0 1 PMID:2446657 -1.14.15.36 * methylococcus capsulatus 706000.0 2 PMID:12235134 -1.14.15.39 * streptomyces coelicolor 55000.0 1 PMID:22151149 -1.14.15.4 * absidia caerulea 60000.0 1 PMID:8268203 -1.14.15.4 * aquarana catesbeiana 51000.0 1 PMID:7744036 -1.14.15.4 * bos taurus 1000000.0 9 PMID:2176837;PMID:3485096;PMID:6978716;PMID:7556158;PMID:889836 -1.14.15.4 * curvularia lunata 60000.0 1 PMID:8268203 -1.14.15.4 * homo sapiens 55890.0 4 PMID:18215163;PMID:22446688;PMID:7663533 -1.14.15.4 * rattus norvegicus 51500.0 5 PMID:11796518;PMID:2738055;PMID:2789017 -1.14.15.4 * sus scrofa 46000.0 1 PMID:3485096 -1.14.15.44 * daphnia sinensis 60820.0 1 PMID:36635746 -1.14.15.6 * anguilla japonica 59000.0 1 PMID:16168415 -1.14.15.6 * bos taurus 850000.0 25 PMID:1131251;PMID:12823901;PMID:18360810;PMID:184090;PMID:4723901;PMID:4723902;PMID:6244284 -1.14.15.6 * capra aegagrus 52000.0 1 PMID:18360810 -1.14.15.6 * homo sapiens 120000.0 3 PMID:12823901;PMID:19342447 -1.14.15.6 * mus musculus 55000.0 2 PMID:19342447 -1.14.15.6 * mytilus galloprovincialis 51400.0 1 PMID:18340451 -1.14.15.6 * sus scrofa 52000.0 1 PMID:18360810 -1.14.15.7 * bienertia sinuspersici 49000.0 1 * -1.14.15.7 * hordeum vulgare 44800.0 1 PMID:21769646 -1.14.15.7 * oryza sativa 43000.0 1 PMID:22569963 -1.14.15.7 * salicornia europaea 42800.0 1 PMID:21280567 -1.14.15.7 * spinacia oleracea 135000.0 6 PMID:16666757;PMID:9096415 -1.14.15.7 * suaeda aralocaspica 49000.0 1 * -1.14.15.8 * priestia megaterium 52000.0 3 PMID:109432;PMID:17073788;PMID:177422 -1.14.15.9 * rhodobacter capsulatus 65000.0 2 PMID:19136077;PMID:2747617 -1.14.16.1 * bos taurus 51000.0 1 PMID:3600374 -1.14.16.1 * caenorhabditis elegans 50000.0 1 PMID:23457044 -1.14.16.1 * chloroflexus aurantiacus 34000.0 1 PMID:19153779 -1.14.16.1 * chromobacterium violaceum 50000.0 5 PMID:19664549;PMID:23457044;PMID:2885717;PMID:33985;PMID:9748224 -1.14.16.1 * colwellia psychrerythraea 50000.0 1 PMID:23457044 -1.14.16.1 * colwellia psychrerythraea 34h 31000.0 2 PMID:17537732 -1.14.16.1 * homo sapiens 275000.0 19 PMID:17565982;PMID:19629656;PMID:19653802;PMID:21315150;PMID:23296088;PMID:23457044;PMID:24244510;PMID:27049649;PMID:28174686;PMID:3298976;PMID:4074362;PMID:4854919 -1.14.16.1 * legionella pneumophila 64000.0 4 PMID:23049981;PMID:23457044 -1.14.16.1 * leishmania major 50400.0 1 PMID:20887755 -1.14.16.1 * pseudomonas aeruginosa 30300.0 1 PMID:12832796 -1.14.16.1 * pseudomonas fluorescens 31140.0 2 PMID:34868217 -1.14.16.1 * pseudomonas sp. 28000.0 2 PMID:1158876 -1.14.16.1 * rattus norvegicus 240000.0 12 PMID:19653802;PMID:20951114;PMID:23296088;PMID:23457044;PMID:27145334;PMID:3600372;PMID:7407194;PMID:7436425 -1.14.16.2 * bactrocera dorsalis 65300.0 1 PMID:28941310 -1.14.16.2 * bombyx mori 66200.0 1 * -1.14.16.2 * bos taurus 390000.0 9 PMID:2443076;PMID:2861203;PMID:2885718;PMID:2894860;PMID:6117320;PMID:6127111 -1.14.16.2 * homo sapiens 481800.0 10 PMID:16581181;PMID:18419768;PMID:22659380;PMID:24334288;PMID:27224548;PMID:30411798;PMID:7822259 -1.14.16.2 * manduca sexta 250000.0 2 PMID:17967351 -1.14.16.2 * mucuna pruriens var. utilis 55000.0 1 PMID:20300771 -1.14.16.2 * mus musculus 62000.0 1 PMID:19429176 -1.14.16.2 * rattus norvegicus 300000.0 13 PMID:1967606;PMID:24334288;PMID:2443076;PMID:2861203;PMID:2885718;PMID:2885719;PMID:2885720;PMID:6120836;PMID:6127111 -1.14.16.2 * schistosoma japonicum 54000.0 1 PMID:21556690 -1.14.16.2 * toxoplasma gondii 62400.0 1 PMID:32244791 -1.14.16.2 * tribolium castaneum 60000.0 1 PMID:20080183 -1.14.16.4 * bos taurus 30000.0 1 PMID:4429558 -1.14.16.4 * danio rerio 90000.0 1 PMID:23754283 -1.14.16.4 * homo sapiens 274000.0 12 PMID:10525150;PMID:15663479;PMID:16185653;PMID:16581181;PMID:17181551;PMID:19816759 -1.14.16.4 * macaca mulatta 50000.0 1 PMID:18593594 -1.14.16.4 * micropogonias undulatus 56000.0 2 PMID:19015006 -1.14.16.4 * mus musculus 280000.0 5 PMID:17622221;PMID:21105877;PMID:3110559;PMID:6809461 -1.14.16.4 * oryctolagus cuniculus 240000.0 6 PMID:1126946 -1.14.16.4 * pseudomonas fluorescens 31140.0 2 PMID:34868217 -1.14.16.4 * ralstonia solanacearum 162000.0 1 PMID:19304791 -1.14.16.4 * rattus norvegicus 300000.0 5 PMID:3600387;PMID:3996408;PMID:7060568 -1.14.16.4 * schistosoma mansoni 240000.0 2 PMID:10419488 -1.14.16.4 * thunnus albacares 280000.0 2 PMID:9159879 -1.14.16.5 * caenorhabditis elegans 40500.0 1 PMID:23441072 -1.14.16.5 * danio rerio 40500.0 1 PMID:23441072 -1.14.16.5 * homo sapiens 60000.0 1 PMID:22220568 -1.14.16.5 * mus musculus 48000.0 1 PMID:23743196 -1.14.16.5 * rattus norvegicus 400000.0 3 PMID:23441072;PMID:3989395;PMID:6840084 -1.14.16.6 * pseudomonas putida 91000.0 1 PMID:9909 -1.14.17.1 * azumapecten farreri 68480.0 1 PMID:20933600 -1.14.17.1 * bos taurus 290000.0 6 PMID:4778938;PMID:5846992;PMID:6795996;PMID:8286345;PMID:8889820;PMID:8914988 -1.14.17.1 * gallus gallus 316000.0 2 PMID:7326235 -1.14.17.1 * homo sapiens 610000.0 4 PMID:21209083;PMID:567644 -1.14.17.1 * mus musculus 75000.0 1 PMID:19079842 -1.14.17.1 * rattus norvegicus 800000.0 7 PMID:19079842;PMID:6733150;PMID:7411149 -1.14.17.1 * sinonovacula constricta 64500.0 1 PMID:32006597 -1.14.17.3 * aplysia californica 60000.0 2 PMID:7099265;PMID:8632187 -1.14.17.3 * bos taurus 69000.0 5 PMID:3944110;PMID:7820069 -1.14.17.3 * homo sapiens 100000.0 2 PMID:12699694;PMID:18832192 -1.14.17.3 * mus musculus 87000.0 1 PMID:19022883 -1.14.17.3 * rattus norvegicus 125000.0 12 PMID:15539631;PMID:16448835;PMID:16931045;PMID:18818385;PMID:1898062;PMID:2211657;PMID:2994573;PMID:3341777;PMID:7540562 -1.14.17.3 * sus scrofa 92000.0 4 PMID:2732216;PMID:3691506;PMID:7099265;PMID:8632187 -1.14.17.3 * xenopus laevis 43000.0 4 PMID:12509982;PMID:2265607;PMID:3729962 -1.14.17.4 * brassica rapa 36800.0 2 PMID:15086827 -1.14.17.4 * cucumis melo 41000.0 1 * -1.14.17.4 * malus domestica 39000.0 4 PMID:1409700;PMID:19223050 -1.14.17.4 * pseudotsuga menziesii 35800.0 1 PMID:16705404 -1.14.17.4 * solanum lycopersicum 35820.0 1 * -1.14.17.4 * trifolium repens 40000.0 2 * -1.14.18.1 * aeromonas media 58000.0 1 PMID:18931836 -1.14.18.1 * agaricus bisporus 134000.0 17 PMID:15968468;PMID:17602775;PMID:17605157;PMID:18500813;PMID:21543865;PMID:26919530;PMID:28322963;PMID:28390091 -1.14.18.1 * annona cherimola 67810.0 1 PMID:17907770 -1.14.18.1 * aspergillus nidulans 50000.0 2 PMID:2126551 -1.14.18.1 * bacillus thuringiensis 14000.0 1 PMID:15482430 -1.14.18.1 * beta vulgaris 41000.0 2 PMID:15968468 -1.14.18.1 * brassica oleracea 57000.0 2 * -1.14.18.1 * calliphora vicina 75000.0 1 PMID:812490 -1.14.18.1 * charybdis japonica 80000.0 3 PMID:19010437 -1.14.18.1 * colocasia esculenta 55000.0 2 PMID:32676302 -1.14.18.1 * crocus sativus 150000.0 3 * -1.14.18.1 * daucus carota 36000.0 1 * -1.14.18.1 * dioscorea alata 61000.0 2 PMID:32676302 -1.14.18.1 * dioscorea bulbifera 115000.0 2 * -1.14.18.1 * dioscorea cayenensis subsp. rotundata 107000.0 3 PMID:32676302 -1.14.18.1 * dioscorea praehensilis 61000.0 2 PMID:32676302 -1.14.18.1 * dugesia japonica 300000.0 2 PMID:20462518 -1.14.18.1 * gallus gallus 66000.0 2 PMID:6432056;PMID:8612714 -1.14.18.1 * glycine max 45000.0 1 PMID:16664865 -1.14.18.1 * halocynthia roretzi 62000.0 2 PMID:32019134;PMID:9787768 -1.14.18.1 * homo sapiens 66700.0 4 PMID:10904869;PMID:15968468;PMID:32019134;PMID:416956;PMID:9787768 -1.14.18.1 * illex argentinus 140200.0 8 PMID:14511385 -1.14.18.1 * juglans regia 39047.0 2 PMID:24613318 -1.14.18.1 * lactuca sativa 188000.0 4 PMID:11600037;PMID:16664865 -1.14.18.1 * lathyrus oleraceus 45000.0 1 PMID:16664865 -1.14.18.1 * lentinula boryana 47000.0 3 * -1.14.18.1 * lentinula edodes 55000.0 8 PMID:8987542 -1.14.18.1 * lithobates pipiens 33000.0 3 PMID:803496 -1.14.18.1 * lonicera confusa 28800.0 1 * -1.14.18.1 * macrolepiota gracilenta 57300.0 1 * -1.14.18.1 * malpighia glabra 52000.0 2 PMID:26049223 -1.14.18.1 * malus domestica 45000.0 1 PMID:17602775 -1.14.18.1 * malus sp. 46000.0 2 * -1.14.18.1 * mangifera indica 65000.0 1 PMID:25211397 -1.14.18.1 * mesocricetus auratus 69000.0 1 PMID:6437339 -1.14.18.1 * metroxylon sagu 40000.0 1 * -1.14.18.1 * mucuna pruriens 90000.0 2 PMID:24253167 -1.14.18.1 * mus musculus 80000.0 5 PMID:17850513;PMID:2510599 -1.14.18.1 * musa cavendishii 60000.0 1 * -1.14.18.1 * musa x paradisiaca 40000.0 1 PMID:21442554 -1.14.18.1 * musca domestica 330000.0 3 * -1.14.18.1 * mushroom 128000.0 4 * -1.14.18.1 * mycothermus thermophilus 320000.0 2 PMID:18369615 -1.14.18.1 * neoboletus erythropus 40000.0 1 * -1.14.18.1 * neurospora crassa 46000.0 2 PMID:15968468;PMID:6210696 -1.14.18.1 * nicotiana tabacum 45000.0 1 PMID:16664865 -1.14.18.1 * olea europaea 42000.0 1 * -1.14.18.1 * pelophylax lessonae 200000.0 3 PMID:19101648 -1.14.18.1 * penaeus japonicus 160000.0 1 * -1.14.18.1 * phaseolus lunatus 45000.0 1 PMID:16664865 -1.14.18.1 * pholiota microspora 42000.0 2 PMID:17617709 -1.14.18.1 * pinus densiflora 65000.0 3 PMID:9713694 -1.14.18.1 * pleurotus ostreatus 67000.0 1 PMID:7763931 -1.14.18.1 * populus nigra 60000.0 1 * -1.14.18.1 * priestia megaterium 70000.0 4 PMID:19672047;PMID:20823537;PMID:21040728 -1.14.18.1 * prunus armeniaca 56200.0 1 PMID:10198084 -1.14.18.1 * prunus domestica subsp. insititia 50000.0 1 PMID:32097726;PMID:35015975 -1.14.18.1 * prunus persica 60000.0 1 PMID:17994689 -1.14.18.1 * pseudomonas putida 39000.0 2 * -1.14.18.1 * ralstonia solanacearum 55000.0 1 PMID:23381872 -1.14.18.1 * schistosoma japonicum 56800.0 4 PMID:18972131 -1.14.18.1 * scyllarides latus 440000.0 2 PMID:16010551 -1.14.18.1 * solanum lycopersicum 45000.0 2 PMID:15659188;PMID:16664865 -1.14.18.1 * solanum tuberosum 50000.0 2 PMID:17602775;PMID:32097726;PMID:35015975 -1.14.18.1 * spinacia oleracea 150000.0 2 * -1.14.18.1 * streptomyces antibioticus 36000.0 3 PMID:3932128 -1.14.18.1 * streptomyces glaucescens 30900.0 2 PMID:15968468;PMID:6804598 -1.14.18.1 * streptomyces refuineus 37900.0 2 PMID:21919439 -1.14.18.1 * streptomyces sp. 36000.0 3 PMID:10737179;PMID:3928616 -1.14.18.1 * thermomicrobium roseum 90000.0 2 PMID:24253167 -1.14.18.1 * trametes sanguinea 45000.0 2 PMID:15659188;PMID:17602775 -1.14.18.1 * trichoderma reesei 45000.0 3 PMID:16939623;PMID:17562370;PMID:17602775 -1.14.18.1 * trifolium pratense 65000.0 4 PMID:18069787 -1.14.18.1 * triticum aestivum 115000.0 3 * -1.14.18.1 * uncultured marine bacterium 67000.0 1 * -1.14.18.1 * vaccinium corymbosum 220000.0 3 PMID:33267982 -1.14.18.1 * vibrio tyrosinaticus 40000.0 2 PMID:4208174 -1.14.18.1 * vicia faba 45000.0 1 PMID:16664865 -1.14.18.1 * vigna radiata 45000.0 1 PMID:16664865 -1.14.18.1 * vitis vinifera 38000.0 1 PMID:25863609 -1.14.18.1 * xenopus laevis 230000.0 3 PMID:3930497 -1.14.18.2 * homo sapiens 75000.0 1 PMID:19890979 -1.14.18.2 * mus musculus 64000.0 4 PMID:1587278;PMID:7841794;PMID:8112313;PMID:8132639 -1.14.18.2 * sus scrofa 65000.0 2 PMID:7881182 -1.14.18.3 * methylococcus capsulatus 660000.0 44 PMID:10896210;PMID:12634423;PMID:16101279;PMID:17223785;PMID:17444606;PMID:18605740;PMID:21419922;PMID:22484247;PMID:24942740;PMID:25185034;PMID:26275807;PMID:8576034;PMID:9525893 -1.14.18.3 * methylocystis sp. 450000.0 4 PMID:10896210;PMID:21419922;PMID:22484247;PMID:24942740 -1.14.18.3 * methylomicrobium album 45000.0 3 PMID:10896210;PMID:21419922;PMID:22484247 -1.14.18.3 * methylosinus trichosporium 40000.0 3 PMID:21419924 -1.14.18.4 * ricinus communis 44000.0 1 PMID:7624314 -1.14.18.5 * homo sapiens 41200.0 2 PMID:15063729 -1.14.18.6 * mus musculus 71800.0 2 PMID:15658937 -1.14.18.9 * homo sapiens 75000.0 1 PMID:8663358 -1.14.18.9 * rhizophagus intraradices 35000.0 1 PMID:19285148 -1.14.18.9 * saccharomyces cerevisiae 75000.0 1 PMID:8663358 -1.14.19.1 * cyprinus carpio 33800.0 3 PMID:10637192;PMID:8629000;PMID:8765141 -1.14.19.1 * gallus gallus 33600.0 1 PMID:36392;PMID:6116157 -1.14.19.1 * helianthus annuus 35000.0 1 * -1.14.19.1 * homo sapiens 58000.0 3 PMID:15907797;PMID:16213227 -1.14.19.1 * mesocricetus auratus 40000.0 1 PMID:18084785 -1.14.19.1 * mus musculus 41000.0 2 PMID:16275639;PMID:18609446;PMID:19066317 -1.14.19.1 * mycobacterium tuberculosis 75000.0 1 PMID:18723625 -1.14.19.1 * picea glauca 43700.0 1 PMID:12208502 -1.14.19.1 * plasmodium falciparum 114000.0 1 PMID:19707292 -1.14.19.1 * pseudoalteromonas sp. 43400.0 1 * -1.14.19.1 * rattus norvegicus 55000.0 6 PMID:18609446;PMID:19066317;PMID:332564;PMID:36392;PMID:4373719;PMID:6116158 -1.14.19.1 * spinacia oleracea 40000.0 1 * -1.14.19.1 * sus scrofa 41000.0 1 PMID:18609446 -1.14.19.11 * coriandrum sativum 36000.0 1 PMID:12232129 -1.14.19.14 * calendula officinalis 43600.0 1 PMID:11161042 -1.14.19.16 * punica granatum 45800.0 1 PMID:12354116 -1.14.19.17 * rattus norvegicus 40000.0 1 PMID:17716801 -1.14.19.18 * kluyveromyces lactis 67100.0 2 PMID:12402089 -1.14.19.18 * lachancea kluyveri 67100.0 2 PMID:12402089 -1.14.19.2 * arabidopsis thaliana 50500.0 9 PMID:17072561;PMID:19716420 -1.14.19.2 * bassia scoparia 49000.0 2 PMID:11171147 -1.14.19.2 * carthamus tinctorius 68000.0 2 PMID:7118934 -1.14.19.2 * chromochloris zofingiensis 47040.0 1 PMID:22855030 -1.14.19.2 * cinnamomum longepaniculatum 43500.0 2 * -1.14.19.2 * helianthus annuus 45000.0 1 PMID:12651018 -1.14.19.2 * jatropha curcas 45510.0 2 PMID:16642305 -1.14.19.2 * pelargonium x hortorum 39000.0 1 PMID:8710947 -1.14.19.2 * ricinus communis 75000.0 2 PMID:8460163 -1.14.19.20 * homo sapiens 30000.0 1 * -1.14.19.21 * tetrahymena thermophila 63000.0 1 PMID:25681633 -1.14.19.22 * carthamus tinctorius 43600.0 1 * -1.14.19.22 * davidia involucrata 44300.0 1 * -1.14.19.22 * helianthus annuus 52000.0 1 PMID:7588718 -1.14.19.22 * olea europaea 43900.0 1 * -1.14.19.22 * oryza sativa 44340.0 1 * -1.14.19.22 * pinguiochrysis pyriformis 51000.0 1 PMID:21705343 -1.14.19.23 * arabidopsis thaliana 47727.0 1 PMID:7846158 -1.14.19.23 * spinacia oleracea 40000.0 1 PMID:7948918 -1.14.19.27 * nostoc sp. 33200.0 1 PMID:17697671 -1.14.19.28 * arabidopsis thaliana 36400.0 2 PMID:9559566 -1.14.19.28 * thermostichus vulcanus 32000.0 1 PMID:10937442 -1.14.19.3 * acanthopagrus schlegelii 51800.0 1 PMID:24052399 -1.14.19.3 * cunninghamella echinulata 52000.0 1 PMID:19884765 -1.14.19.3 * limnospira platensis 47000.0 1 PMID:17160624 -1.14.19.3 * rattus norvegicus 68000.0 3 PMID:11988075;PMID:7212717 -1.14.19.3 * rhizopus stolonifer 52410.0 2 PMID:19152021;PMID:23821293 -1.14.19.30 * mortierella alpina 56000.0 1 PMID:9668087 -1.14.19.31 * diacronema lutheri 49000.0 1 PMID:14572666 -1.14.19.31 * thraustochytrium sp. 49800.0 1 PMID:11397798 -1.14.19.35 * arabidopsis thaliana 51172.0 2 PMID:7846164;PMID:8226956 -1.14.19.35 * glycine max 39000.0 1 PMID:17951449 -1.14.19.35 * helianthus annuus 50800.0 1 PMID:17064923 -1.14.19.36 * nostoc sp. 41800.0 1 PMID:17697671 -1.14.19.36 * synechocystis sp. 41900.0 1 PMID:7524725 -1.14.19.41 * arabidopsis thaliana 55723.0 2 PMID:16531502 -1.14.19.41 * nakaseomyces glabratus 59000.0 1 PMID:10390230 -1.14.19.41 * physcomitrium patens 57410.0 2 PMID:19306103 -1.14.19.41 * saccharomyces cerevisiae 58000.0 1 PMID:8543054 -1.14.19.41 * solanum lycopersicum 57511.0 2 PMID:16531502 -1.14.19.43 * thraustochytrium sp. 59100.0 1 PMID:11397798 -1.14.19.44 * homo sapiens 54000.0 1 PMID:22619218 -1.14.19.44 * papio anubis 54000.0 1 PMID:22619218 -1.14.19.45 * bacillus cereus 39805.0 1 PMID:23913431 -1.14.19.45 * synechocystis sp. 40300.0 1 PMID:8155883 -1.14.19.45 * trichormus variabilis 41300.0 1 PMID:8155883 -1.14.19.46 * limnospira platensis 50000.0 2 PMID:15241633;PMID:16575563 -1.14.19.47 * amylomyces rouxii 60625.0 1 PMID:11112411 -1.14.19.47 * mortierella alpina 51815.0 1 PMID:10570972 -1.14.19.49 * kitasatospora aureofaciens 66300.0 1 PMID:23800859 -1.14.19.5 * ascotis selenaria 40500.0 2 PMID:24211206 -1.14.19.5 * ostrinia latipennis 37800.0 1 PMID:21444802 -1.14.19.59 * streptomyces toxytricini 59000.0 1 PMID:21424165 -1.14.19.6 * arachis hypogaea 43000.0 1 PMID:17469780 -1.14.19.6 * pinguiochrysis pyriformis 51100.0 1 PMID:21705343 -1.14.19.6 * synechococcus sp. 40700.0 1 PMID:8155883 -1.14.19.6 * synechocystis sp. 66000.0 4 PMID:20377689;PMID:7890027 -1.14.19.6 * umbelopsis isabellina 43000.0 1 PMID:16733854 -1.14.19.64 * argemone mexicana 57450.0 1 PMID:21094631 -1.14.19.65 * argemone mexicana 57450.0 1 PMID:21094631 -1.14.19.66 * berberis stolonifera 55474.0 2 PMID:7892226;PMID:8380416 -1.14.19.67 * papaver somniferum 56000.0 2 PMID:19567876;PMID:24104569 -1.14.19.67 * sus scrofa 50000.0 1 * -1.14.19.68 * argemone mexicana 57450.0 1 PMID:21094631 -1.14.19.68 * coptis chinensis 55290.0 1 * -1.14.19.70 * mycobacterium tuberculosis 91000.0 5 PMID:12237220;PMID:23675886 -1.14.19.74 * sesamum indicum 50000.0 1 * -1.14.19.9 * pseudomonas fluorescens 61641.0 3 PMID:15272170;PMID:16544142 -1.14.20.1 * actinomyces sp. 28900.0 1 PMID:19374992 -1.14.20.1 * amycolatopsis lactamdurans 28000.0 2 PMID:3446748 -1.14.20.1 * hapsidospora chrysogena 43000.0 6 PMID:14734549;PMID:3558321;PMID:3663194 -1.14.20.1 * streptomyces clavuligerus 60000.0 11 PMID:10222202;PMID:12586400;PMID:19374992;PMID:2644235;PMID:2656705;PMID:3997672 -1.14.20.1 * streptomyces jumonjinensis 60000.0 2 PMID:12586400 -1.14.20.13 * anisodus acutangulus 64000.0 2 PMID:21380527 -1.14.20.13 * atropa belladonna 39369.0 2 PMID:22705021 -1.14.20.13 * brugmansia sanguinea 38768.0 1 PMID:30108978 -1.14.20.13 * hyoscyamus niger 41000.0 1 PMID:3569262 -1.14.20.3 * pectobacterium carotovorum 200000.0 1 PMID:12611886 -1.14.20.4 * brassica juncea 40862.0 1 * -1.14.20.4 * ginkgo biloba 40000.0 1 PMID:18779661 -1.14.20.4 * ipomoea batatas 40450.0 1 * -1.14.20.4 * medicago truncatula 40000.0 1 PMID:17885080 -1.14.20.4 * oryza sativa 41000.0 1 PMID:17157544 -1.14.20.4 * saussurea medusa 40300.0 1 * -1.14.20.5 * oryza sativa 64700.0 3 PMID:18304453 -1.14.20.5 * petroselinum crispum 48000.0 1 PMID:2221917 -1.14.20.5 * populus deltoides 64000.0 1 PMID:19494697 -1.14.20.6 * acacia confusa 38000.0 1 * -1.14.20.6 * arabidopsis thaliana 64000.0 3 PMID:17719613;PMID:19433090 -1.14.20.6 * citrus unshiu 38000.0 2 PMID:12180990;PMID:20033832 -1.14.20.6 * fagopyrum tataricum 40000.0 1 PMID:22563787 -1.14.20.6 * populus deltoides 38000.0 1 PMID:12180990;PMID:20033832 -1.14.20.7 * pseudomonas savastanoi pv. phaseolicola 39370.0 1 PMID:27749027 -1.14.20.7 * pseudomonas syringae 42000.0 4 PMID:1445325;PMID:1770346 -1.14.99.1 * bos taurus 350000.0 2 PMID:11207216;PMID:816795 -1.14.99.1 * gracilaria vermiculophylla 330000.0 2 PMID:23220097 -1.14.99.1 * homo sapiens 75000.0 6 PMID:16185670;PMID:16401081;PMID:17045584;PMID:7947975;PMID:9172778 -1.14.99.1 * mus musculus 65000.0 1 PMID:16581972 -1.14.99.1 * ovis aries 72000.0 6 PMID:16470026;PMID:17140386;PMID:3125548;PMID:6766446;PMID:823151 -1.14.99.1 * rattus norvegicus 72000.0 1 PMID:19060098 -1.14.99.15 * pseudomonas putida 52000.0 2 PMID:3226294;PMID:4850360;PMID:729590 -1.14.99.20 * bos taurus 94000.0 2 PMID:2780546;PMID:7890642;PMID:9256436 -1.14.99.21 * latia neritoides 180000.0 4 * -1.14.99.22 * bombyx mori 103000.0 2 PMID:11082204 -1.14.99.22 * locusta migratoria migratorioides 60000.0 1 PMID:11767943 -1.14.99.24 * mycolicibacterium fortuitum 60000.0 1 PMID:18982265 -1.14.99.24 * mycolicibacterium neoaurum 45370.0 1 PMID:20204712 -1.14.99.24 * nocardia sp. 214000.0 2 PMID:7173200 -1.14.99.29 * bos taurus 33000.0 1 PMID:17391984 -1.14.99.29 * drosophila melanogaster 39000.0 1 PMID:19546244 -1.14.99.29 * homo sapiens 32000.0 1 PMID:16371467 -1.14.99.29 * plasmodium falciparum 46450.0 3 PMID:19740108;PMID:19956997 -1.14.99.29 * plasmodium vivax 39010.0 1 PMID:23505486 -1.14.99.29 * saccharomyces cerevisiae 36000.0 1 PMID:16371467 -1.14.99.29 * trichomonas vaginalis 170000.0 1 PMID:26410361 -1.14.99.35 * aquamicrobium defluvii 220000.0 1 PMID:9531630 -1.14.99.38 * bos taurus 31326.0 1 PMID:22582164 -1.14.99.38 * canis lupus familiaris 30426.0 1 PMID:22582164 -1.14.99.38 * equus caballus 31464.0 1 PMID:22582164 -1.14.99.38 * gallus gallus 32456.0 1 PMID:22582164 -1.14.99.38 * homo sapiens 31745.0 2 PMID:11111082;PMID:22582164 -1.14.99.38 * macaca mulatta 31850.0 1 PMID:22582164 -1.14.99.38 * mus musculus 34700.0 3 PMID:11111082;PMID:19805370;PMID:22582164 -1.14.99.38 * rattus norvegicus 34414.0 1 PMID:22582164 -1.14.99.38 * xenopus tropicalis 31405.0 1 PMID:22582164 -1.14.99.39 * acinetobacter sp. 31000.0 1 * -1.14.99.39 * nitrosomonas europaea 283000.0 4 PMID:19453274 -1.14.99.39 * paracoccus denitrificans 46000.0 2 PMID:8654570 -1.14.99.4 * streptomyces roseochromogenus 65000.0 1 PMID:9056916 -1.14.99.47 * larrea tridentata 66352.0 2 PMID:12960376 -1.14.99.48 * staphylococcus aureus 12500.0 2 PMID:14570922 -1.14.99.53 * bacillus thuringiensis 24150.0 1 PMID:25936286 -1.14.99.53 * bacillus thuringiensis serovar kurstaki 20000.0 1 PMID:25936286 -1.14.99.53 * jonesia denitrificans 15500.0 1 PMID:26763108 -1.14.99.53 * serratia marcescens 21000.0 1 PMID:19267677 -1.14.99.54 * thermoascus aurantiacus 50000.0 1 PMID:31603264 -1.14.99.54 * thermothelomyces thermophilus 32000.0 3 PMID:26185526;PMID:27588039 -1.14.99.55 * aspergillus oryzae 30860.0 1 PMID:25608804 -1.14.99.55 * neurospora crassa 41000.0 1 PMID:25201969 -1.14.99.55 * pyricularia oryzae 37220.0 1 PMID:27397613 -1.14.99.56 * thermothelomyces thermophilus 25000.0 1 PMID:27588039 -1.14.99.57 * mycobacterium tuberculosis 22100.0 1 PMID:31480841 -1.14.99.58 * pseudomonas aeruginosa 23000.0 2 PMID:15310749 -1.14.99.60 * escherichia coli 42953.0 1 PMID:10802164 -1.14.99.63 * haematococcus lacustris 32000.0 1 PMID:8764486 -1.14.99.66 * homo sapiens 100000.0 1 PMID:21510664 -1.14.99.69 * pseudomonas putida 50000.0 1 PMID:32785618 -1.14.99.69 * salmonella enterica subsp. enterica serovar typhimurium 29000.0 1 PMID:23906247 -1.15.1.1 * acanthamoeba castellanii 50000.0 1 PMID:24414928;PMID:31282867 -1.15.1.1 * acholeplasma laidlawii 41500.0 3 PMID:6469219;PMID:7213754 -1.15.1.1 * acidilobus saccharovorans 98500.0 2 PMID:23244732 -1.15.1.1 * aeropyrum pernix 60000.0 7 PMID:10393342;PMID:15734151;PMID:20467245;PMID:21182595;PMID:3691525;PMID:6336758 -1.15.1.1 * afipia carboxydohydrogena 42500.0 2 PMID:9509413 -1.15.1.1 * amaranthus hypochondriacus 28500.0 1 PMID:26129702 -1.15.1.1 * amphiprora kufferathii 59000.0 2 PMID:18557912 -1.15.1.1 * anas platyrhynchos domestica 32000.0 3 PMID:11207434;PMID:12182817;PMID:214140;PMID:29850654;PMID:31176116;PMID:4346527;PMID:8581822 -1.15.1.1 * ascaris suum 73000.0 3 PMID:2721158 -1.15.1.1 * aspergillus flavus 185000.0 2 PMID:8757871 -1.15.1.1 * aspergillus fumigatus 21500.0 5 PMID:10655345;PMID:2226833 -1.15.1.1 * aspergillus nidulans 55000.0 2 PMID:8757871 -1.15.1.1 * aspergillus niger 88000.0 6 PMID:18395490;PMID:8757871 -1.15.1.1 * aspergillus terreus 175000.0 2 PMID:8757871 -1.15.1.1 * azotobacter chroococcum 33000.0 1 PMID:7066332;PMID:7378937 -1.15.1.1 * bacillus sp. (in: firmicutes) 22650.0 1 PMID:21340017 -1.15.1.1 * bacteroides fragilis 43000.0 3 PMID:1851570;PMID:3985629 -1.15.1.1 * bacteroides thetaiotaomicron 46000.0 1 PMID:1851570 -1.15.1.1 * beauveria bassiana 45000.0 1 * -1.15.1.1 * benthodytes marianensis 38000.0 1 PMID:32971171 -1.15.1.1 * bombyx mori 24225.0 3 * -1.15.1.1 * bos taurus 35000.0 6 PMID:16667953;PMID:4324341;PMID:4346527;PMID:4559499 -1.15.1.1 * brassica oleracea 31000.0 2 * -1.15.1.1 * brassica rapa subsp. oleifera 41000.0 2 PMID:7396513 -1.15.1.1 * burkholderia pseudomallei 25000.0 1 PMID:23274991;PMID:23543073 -1.15.1.1 * candida albicans 85000.0 2 PMID:11562375 -1.15.1.1 * canis lupus familiaris 44000.0 3 PMID:11207434;PMID:12182817;PMID:4346527;PMID:8581822 -1.15.1.1 * caulobacter vibrioides 32000.0 2 PMID:16213200 -1.15.1.1 * cereibacter sphaeroides 37400.0 3 PMID:1085167 -1.15.1.1 * chersonesometrus fulvipes 100000.0 2 PMID:1616488;PMID:6336758 -1.15.1.1 * cinnamomum camphora 22931.0 1 PMID:12147259 -1.15.1.1 * citrullus lanatus 112000.0 5 PMID:16668632;PMID:17545229 -1.15.1.1 * clonorchis sinensis 28000.0 4 PMID:15977906 -1.15.1.1 * cordyceps militaris 35100.0 4 PMID:16165406 -1.15.1.1 * crithidia fasciculata 43000.0 3 PMID:6336744 -1.15.1.1 * crypthecodinium cohnii 23652.0 3 PMID:18276189 -1.15.1.1 * cryptosporidium parvum 50000.0 2 PMID:18551319 -1.15.1.1 * curcuma longa 30800.0 2 PMID:18443818 -1.15.1.1 * cyprinus carpio 32400.0 1 PMID:2591201 -1.15.1.1 * danio rerio 24989.0 1 PMID:19501168 -1.15.1.1 * deinococcus radiodurans 22000.0 1 PMID:18247479 -1.15.1.1 * deinococcus radiophilus 51500.0 3 PMID:15106001;PMID:24241319 -1.15.1.1 * deschampsia antarctica 15132.0 1 PMID:19785762 -1.15.1.1 * dirofilaria immitis 36000.0 2 PMID:1775168 -1.15.1.1 * drosophila melanogaster 32500.0 1 PMID:6790543 -1.15.1.1 * escherichia coli 40000.0 4 PMID:1851570;PMID:893415 -1.15.1.1 * exiguobacterium sp. 50000.0 3 PMID:24414928;PMID:31282867 -1.15.1.1 * gallus gallus 32000.0 4 PMID:11207434;PMID:12182817;PMID:214140;PMID:29850654;PMID:31176116;PMID:4346527;PMID:8581822 -1.15.1.1 * geobacillus sp. 130700.0 3 PMID:24242973 -1.15.1.1 * geobacillus stearothermophilus 45000.0 1 * -1.15.1.1 * ginkgo biloba 47000.0 1 PMID:3933430 -1.15.1.1 * gluconobacter cerinus 48000.0 2 * -1.15.1.1 * gordonia bronchialis 80000.0 1 PMID:1851570 -1.15.1.1 * haliotis discus 25000.0 1 PMID:11041352;PMID:23530753 -1.15.1.1 * haliotis diversicolor supertexta 15700.0 1 PMID:18360784 -1.15.1.1 * halobacterium salinarum 38500.0 1 PMID:3341765 -1.15.1.1 * halomonas halmophila 56000.0 2 PMID:2818129 -1.15.1.1 * homo sapiens 88000.0 13 PMID:11207434;PMID:11812217;PMID:12182817;PMID:15358352;PMID:18951903;PMID:20656555;PMID:214140;PMID:2269295;PMID:2738919;PMID:29850654;PMID:31176116;PMID:3972788 -1.15.1.1 * humicola lutea 32000.0 2 PMID:17805512 -1.15.1.1 * hyphantria cunea 15832.0 1 * -1.15.1.1 * ignicoccus hospitalis 14000.0 1 PMID:25476860 -1.15.1.1 * jatropha curcas 69130.0 9 PMID:23586910;PMID:23659174 -1.15.1.1 * klebsiella aerogenes 45000.0 2 PMID:1368658 -1.15.1.1 * kluyveromyces marxianus 34034.0 2 PMID:18040680;PMID:19758847 -1.15.1.1 * laternula elliptica 24800.0 1 PMID:19628043 -1.15.1.1 * lathyrus oleraceus 106000.0 8 PMID:17244628;PMID:24306590;PMID:25887674;PMID:4337330 -1.15.1.1 * lens culinaris 33000.0 1 PMID:16664244 -1.15.1.1 * leptolyngbya boryana 43000.0 3 PMID:164232;PMID:1851570 -1.15.1.1 * limnospira platensis 37400.0 3 PMID:1085167 -1.15.1.1 * macrobrachium nipponense 21700.0 1 * -1.15.1.1 * marchantia paleacea 32600.0 2 PMID:8759916 -1.15.1.1 * marinomonas sp. 48000.0 2 PMID:16369690 -1.15.1.1 * megalodesulfovibrio gigas 186000.0 2 PMID:10633116;PMID:14641572 -1.15.1.1 * meretrix meretrix 21000.0 1 PMID:23053968 -1.15.1.1 * mesocricetus auratus 260000.0 2 PMID:17157046 -1.15.1.1 * metarhizium anisopliae 30700.0 1 PMID:15380557 -1.15.1.1 * methanobacterium bryantii 91000.0 2 PMID:7294823 -1.15.1.1 * methanobrevibacter arboriphilus 80000.0 3 PMID:16615865 -1.15.1.1 * methanosarcina barkeri 25000.0 1 PMID:11041352;PMID:23530753 -1.15.1.1 * methanothermobacter thermautotrophicus 105000.0 2 PMID:1907270 -1.15.1.1 * methylobacillus sp. 44000.0 2 PMID:17646712 -1.15.1.1 * mizuhopecten yessoensis 95000.0 3 PMID:16324874 -1.15.1.1 * mycobacterium sp. 48000.0 3 PMID:21717325 -1.15.1.1 * mycolicibacterium phlei 80000.0 1 PMID:1851570 -1.15.1.1 * mytilus edulis 205000.0 6 PMID:12820627;PMID:26047895 -1.15.1.1 * neurospora crassa 31600.0 4 PMID:17420576;PMID:4337853;PMID:6249266 -1.15.1.1 * niallia circulans 46000.0 3 PMID:15106001;PMID:16662151;PMID:16713057;PMID:24241319;PMID:26047895 -1.15.1.1 * nicotiana sp. 165000.0 1 PMID:10952990 -1.15.1.1 * nicotiana tabacum 22980.0 1 * -1.15.1.1 * nocardia asteroides 100000.0 3 PMID:1616488;PMID:20467245;PMID:6336758 -1.15.1.1 * nostoc sp. 43000.0 2 PMID:15302891 -1.15.1.1 * nuphar lutea 46000.0 1 PMID:16662151;PMID:16713057;PMID:26047895 -1.15.1.1 * panax ginseng 62160.0 2 PMID:20954211 -1.15.1.1 * paracoccus denitrificans 41500.0 3 PMID:6469219;PMID:7066332;PMID:7213754;PMID:7378937 -1.15.1.1 * paralichthys olivaceus 44000.0 2 PMID:21199678 -1.15.1.1 * penaeus japonicus 24800.0 2 PMID:19835962 -1.15.1.1 * perkinsus marinus 24000.0 1 PMID:12782041;PMID:14563869;PMID:16413404 -1.15.1.1 * phanerodontia chrysosporium 44000.0 1 PMID:17646712 -1.15.1.1 * photobacterium damselae subsp. piscicida 39800.0 2 PMID:11041352;PMID:23530753 -1.15.1.1 * photobacterium leiognathi 40000.0 3 PMID:2325128 -1.15.1.1 * phytomonas sp. 66000.0 2 PMID:15267114 -1.15.1.1 * pibocella sp. 36000.0 1 PMID:18557912 -1.15.1.1 * pinus sylvestris 35000.0 3 PMID:16667953;PMID:4324341 -1.15.1.1 * porphyridium purpureum 40000.0 3 PMID:893415 -1.15.1.1 * porphyromonas gingivalis 21500.0 1 PMID:10655345;PMID:2226833 -1.15.1.1 * propionibacterium freudenreichii subsp. shermanii 32000.0 1 PMID:1851570 -1.15.1.1 * providencia alcalifaciens 25000.0 1 PMID:17951985 -1.15.1.1 * pseudoalteromonas haloplanktis 46000.0 4 PMID:16662151;PMID:16713057;PMID:26047895 -1.15.1.1 * pseudomonas putida 40000.0 3 PMID:10633116;PMID:1247598;PMID:14641572 -1.15.1.1 * psidium guajava 40000.0 2 PMID:1851570;PMID:3985629 -1.15.1.1 * pyrobaculum aerophilum 61000.0 3 PMID:10907751;PMID:14563869 -1.15.1.1 * pyrobaculum calidifontis 61000.0 2 PMID:10907751;PMID:12782041;PMID:14563869;PMID:16413404 -1.15.1.1 * radix lethospermi 60000.0 2 PMID:10393342;PMID:15734151;PMID:3691525 -1.15.1.1 * rattus norvegicus 89000.0 7 PMID:10393342;PMID:15734151;PMID:17877538;PMID:20656555;PMID:26314;PMID:3691525;PMID:3972788 -1.15.1.1 * rhodothermus sp. 52000.0 3 PMID:17987330 -1.15.1.1 * rhodotorula mucilaginosa 49300.0 1 PMID:28639705 -1.15.1.1 * saccharolobus solfataricus 88000.0 8 PMID:10601872;PMID:11248699;PMID:19759909;PMID:9931259 -1.15.1.1 * saccharomyces cerevisiae 96000.0 9 PMID:11207434;PMID:12182817;PMID:238997;PMID:4346514;PMID:4346527;PMID:8581822 -1.15.1.1 * sardinella aurita 40000.0 1 * -1.15.1.1 * scedosporium apiospermum 16400.0 1 PMID:17395518 -1.15.1.1 * sinorhizobium meliloti 43000.0 2 PMID:10419947 -1.15.1.1 * solanum lycopersicum 43000.0 7 PMID:3967667 -1.15.1.1 * sonneratia alba 25000.0 1 PMID:23274991;PMID:23543073 -1.15.1.1 * spinacia oleracea 52000.0 3 PMID:15106001;PMID:24241319;PMID:4354621 -1.15.1.1 * spirometra erinaceieuropaei 42000.0 3 PMID:20076970 -1.15.1.1 * streptococcus mutans 40250.0 4 PMID:4324341;PMID:4559499 -1.15.1.1 * sulfitobacter sp. 40000.0 1 PMID:18557912 -1.15.1.1 * sulfolobus acidocaldarius 87000.0 6 PMID:8674972;PMID:8922285 -1.15.1.1 * sus scrofa 69000.0 3 PMID:20820880;PMID:23522069 -1.15.1.1 * thermoascus aurantiacus 68000.0 4 PMID:17420576;PMID:19229500;PMID:4337853 -1.15.1.1 * thermochaetoides thermophila 94400.0 4 PMID:18751544;PMID:20823534;PMID:24316252 -1.15.1.1 * thermomyces lanuginosus 89100.0 2 PMID:15290327 -1.15.1.1 * thermoplasma acidophilum 82000.0 1 PMID:1851570 -1.15.1.1 * thermus aquaticus 80000.0 2 PMID:14828;PMID:659388 -1.15.1.1 * thermus filiformis 25000.0 1 PMID:11041352;PMID:23530753 -1.15.1.1 * thermus thermophilus 84000.0 3 PMID:14828;PMID:21197558;PMID:659388 -1.15.1.1 * triticum aestivum 46000.0 2 PMID:18698793 -1.15.1.1 * trypanosoma brucei 36031.0 4 PMID:12782041;PMID:14563869;PMID:16413404 -1.15.1.1 * trypanosoma cruzi 60000.0 4 PMID:18592100 -1.15.1.1 * ulva linza 46000.0 1 PMID:16662151;PMID:16713057;PMID:26047895 -1.15.1.1 * uncultured bacterium 214000.0 7 PMID:17262208 -1.15.1.1 * vigna unguiculata 54000.0 3 PMID:14512518 -1.15.1.1 * virgibacillus halodenitrificans 41400.0 2 PMID:15106001;PMID:24241319 -1.15.1.1 * withania somnifera 34000.0 3 PMID:21695487 -1.15.1.1 * yersinia enterocolitica 82000.0 3 PMID:23704955 -1.15.1.1 * zea mays 90000.0 8 PMID:16663180;PMID:6784678 -1.15.1.2 * archaeoglobus fulgidus 30000.0 3 PMID:17066300;PMID:20208170 -1.15.1.2 * desulfarculus baarsii 27000.0 2 PMID:10617593 -1.15.1.2 * desulfovibrio desulfuricans 14000.0 1 * -1.15.1.2 * filifactor alocis 64000.0 1 PMID:32513978 -1.15.1.2 * ignicoccus hospitalis 14000.0 1 PMID:25476860 -1.15.1.2 * megalodesulfovibrio gigas 29000.0 1 PMID:24038730 -1.15.1.2 * methanosarcina mazei 20000.0 2 PMID:21138528 -1.15.1.2 * pyrococcus furiosus 14323.0 3 PMID:10514376;PMID:10704199 -1.15.1.2 * treponema pallidum 26000.0 5 PMID:10874033 -1.16.1.1 * acidithiobacillus ferrooxidans 130000.0 3 * -1.16.1.1 * azotobacter chroococcum 142000.0 3 * -1.16.1.1 * bacillus sp. (in: firmicutes) 69000.0 1 PMID:8338845 -1.16.1.1 * escherichia coli 110000.0 2 PMID:6340733 -1.16.1.1 * klebsiella pneumoniae 190000.0 2 * -1.16.1.1 * lysinibacillus sphaericus 120000.0 1 PMID:28894951 -1.16.1.1 * penicillium sp. 58000.0 1 * -1.16.1.1 * plasmid r100 66200.0 1 * -1.16.1.1 * pseudomonas aeruginosa 123000.0 6 PMID:20828160;PMID:6277900;PMID:6436233 -1.16.1.1 * serratia marcescens 190000.0 2 * -1.16.1.1 * yersinia enterolytica 200000.0 2 PMID:8467420 -1.16.1.10 * archaeoglobus fulgidus 40000.0 3 PMID:10593977 -1.16.1.2 * mycobacterium avium subsp. paratuberculosis 17000.0 1 PMID:9453631 -1.16.1.8 * homo sapiens 78000.0 4 PMID:11466310;PMID:17892308;PMID:9501215 -1.16.1.9 * arabidopsis thaliana 81500.0 1 PMID:10067892 -1.16.1.9 * escherichia coli 32412.0 2 PMID:18765906 -1.16.1.9 * lathyrus oleraceus 80500.0 1 PMID:12011340 -1.16.1.9 * synechocystis sp. 60000.0 2 PMID:21221720 -1.16.2.1 * shewanella oneidensis 210000.0 2 PMID:17675441;PMID:20018742 -1.16.3.1 * achromobacter sp. dh1f 228000.0 1 PMID:30198888 -1.16.3.1 * anser sp. 121300.0 3 PMID:2829726 -1.16.3.1 * bombyx mori 670000.0 1 PMID:29793044 -1.16.3.1 * bos taurus 125000.0 4 PMID:6280673 -1.16.3.1 * camponotus sericeiventris 669000.0 1 PMID:29594412 -1.16.3.1 * caretta caretta 145000.0 1 PMID:2337357 -1.16.3.1 * equus sp. 130000.0 2 PMID:11042176;PMID:2829726;PMID:6280673;PMID:952866 -1.16.3.1 * gallus sp. 158000.0 5 PMID:2829726;PMID:2834379;PMID:4037797;PMID:5964981 -1.16.3.1 * homo sapiens 2000000.0 49 PMID:11042176;PMID:12351628;PMID:15715949;PMID:16274220;PMID:2154449;PMID:2829726;PMID:3237086;PMID:3993922;PMID:4037797;PMID:4098342;PMID:4653953;PMID:6280673;PMID:7425301;PMID:775938;PMID:952866;PMID:952897 -1.16.3.1 * leptolyngbya sp. o-77 150000.0 1 PMID:32170832 -1.16.3.1 * mycobacterium tuberculosis 56000.0 1 PMID:23772064 -1.16.3.1 * oryctolagus cuniculus 130000.0 2 PMID:11042176;PMID:2829726;PMID:6280673;PMID:952866 -1.16.3.1 * rattus norvegicus 130000.0 2 PMID:11042176;PMID:2829726;PMID:6280673;PMID:952866 -1.16.3.1 * saccharomyces cerevisiae 150000.0 7 PMID:9162052;PMID:9722559 -1.16.3.1 * sus scrofa 150000.0 3 PMID:11042176;PMID:2829726;PMID:6280673;PMID:775938;PMID:952866 -1.16.3.1 * thermosynechococcus vestitus 20900.0 1 PMID:20088882 -1.16.3.2 * escherichia coli 465000.0 4 PMID:11254384;PMID:8281950 -1.16.3.2 * halobacterium salinarum 291500.0 2 PMID:12147354 -1.16.3.3 * bacillus sp. pl-12 230000.0 2 PMID:28963463 -1.16.3.4 * rhodococcus erythropolis 55000.0 2 PMID:23485678 -1.16.9.1 * acidithiobacillus ferrooxidans 50000.0 5 PMID:11741873;PMID:18632666;PMID:8049223;PMID:9809418 -1.16.99.1 * methanosarcina barkeri 71000.0 1 PMID:19043046 -1.17.1.1 * yersinia pseudotuberculosis 70000.0 5 PMID:4343157 -1.17.1.10 * burkholderia stabilis 340000.0 2 PMID:6822536 -1.17.1.10 * granulicella mallensis 79000.0 2 PMID:26104866 -1.17.1.10 * neomoorella thermoacetica 340000.0 4 PMID:6822536;PMID:713844 -1.17.1.11 * gottschalkia acidurici 99000.0 4 PMID:23872566 -1.17.1.3 * desmodium uncinatum 52000.0 4 PMID:12788945 -1.17.1.4 * acinetobacter baumannii 290000.0 1 PMID:11005854;PMID:27537049 -1.17.1.4 * arabidopsis thaliana 300000.0 2 PMID:14726515 -1.17.1.4 * arthrobacter luteolus 160000.0 1 PMID:27537049 -1.17.1.4 * bombyx mori 260000.0 1 PMID:30286706 -1.17.1.4 * bos taurus 290000.0 3 PMID:11005854;PMID:15679468;PMID:27537049 -1.17.1.4 * camelus dromedarius 145300.0 1 PMID:16026028 -1.17.1.4 * colias eurytheme 300000.0 1 PMID:4334999 -1.17.1.4 * delftia acidovorans 287000.0 6 PMID:1191668;PMID:8611534 -1.17.1.4 * drosophila melanogaster 300000.0 4 PMID:197387 -1.17.1.4 * enterobacter cloacae 128000.0 1 PMID:27537049 -1.17.1.4 * escherichia coli 160000.0 1 PMID:27537049 -1.17.1.4 * eubacterium barkeri 530000.0 4 PMID:10491134 -1.17.1.4 * gallus gallus 300000.0 4 PMID:4294045;PMID:6585363 -1.17.1.4 * glycine max 325000.0 3 PMID:6573870;PMID:6960807 -1.17.1.4 * gottschalkia acidurici 224000.0 6 * -1.17.1.4 * gottschalkia purinilytica 529000.0 4 PMID:10860985 -1.17.1.4 * homo sapiens 148000.0 2 PMID:15679468;PMID:8248161 -1.17.1.4 * lathyrus oleraceus 300000.0 4 PMID:14726515;PMID:18538891 -1.17.1.4 * mus musculus 150000.0 1 PMID:10545219;PMID:15453470 -1.17.1.4 * neurospora crassa 357000.0 2 PMID:147274 -1.17.1.4 * ovis aries 150000.0 1 PMID:10545219;PMID:15453470 -1.17.1.4 * pseudomonas putida 580000.0 10 PMID:11341925;PMID:3860496 -1.17.1.4 * pseudomonas synxantha 540000.0 3 * -1.17.1.4 * rattus sp. 300000.0 4 PMID:176939;PMID:176940;PMID:2557023;PMID:3478001 -1.17.1.4 * rhodobacter capsulatus 345000.0 3 PMID:27537049 -1.17.1.4 * streptomyces cyanogenus 125000.0 2 PMID:479130 -1.17.1.4 * sus scrofa 150000.0 1 PMID:24040113 -1.17.1.4 * triticum aestivum 350000.0 1 * -1.17.1.4 * veillonella atypica 250000.0 5 PMID:6061702;PMID:8706691 -1.17.1.5 * bacillus sp. (in: firmicutes) 400000.0 1 PMID:5128334 -1.17.1.5 * clostridium sp. 300000.0 1 PMID:4388026 -1.17.1.5 * comamonas testosteroni 82389.0 3 PMID:20119845 -1.17.1.5 * eubacterium barkeri 160000.0 9 PMID:19549881;PMID:8278371;PMID:8555176 -1.17.1.5 * neobacillus niacini 340000.0 4 * -1.17.1.5 * pseudomonas fluorescens 100000.0 2 * -1.17.1.5 * pseudomonas putida 130000.0 1 PMID:19118407 -1.17.1.8 * arabidopsis thaliana 29200.0 1 PMID:17727612 -1.17.1.8 * bacillus cereus 155000.0 1 PMID:19431 -1.17.1.8 * bacillus subtilis 74000.0 2 PMID:236291 -1.17.1.8 * bartonella henselae 114000.0 2 PMID:18710263;PMID:26815040;PMID:27917836 -1.17.1.8 * brucella abortus 30780.0 1 PMID:29302824 -1.17.1.8 * corynebacterium glutamicum 34000.0 1 * -1.17.1.8 * escherichia coli 110000.0 8 PMID:18710263;PMID:26815040;PMID:27917836;PMID:4151489;PMID:6094578;PMID:7893644;PMID:9398235 -1.17.1.8 * lactiplantibacillus plantarum 28500.0 1 * -1.17.1.8 * neisseria meningitidis 113000.0 1 PMID:29187521 -1.17.1.8 * priestia megaterium 150000.0 1 PMID:19431 -1.17.1.8 * pseudomonas aeruginosa 120000.0 3 * -1.17.1.8 * selaginella moellendorffii 64200.0 1 PMID:29187521 -1.17.1.8 * staphylococcus aureus 27622.0 3 PMID:20057072;PMID:22776412 -1.17.1.8 * trichormus variabilis 139000.0 1 PMID:27845445 -1.17.1.8 * vitis vinifera 62900.0 1 PMID:29187521 -1.17.1.8 * zea mays 84000.0 1 PMID:16663283 -1.17.1.9 * [candida] boidinii 100000.0 5 PMID:1248477;PMID:24034888;PMID:27444330;PMID:28201611;PMID:29083897 -1.17.1.9 * [candida] methylica 70000.0 4 PMID:19647736;PMID:227687;PMID:4054127;PMID:4372234 -1.17.1.9 * ancylobacter aquaticus 100000.0 2 PMID:12784610 -1.17.1.9 * bacillus sp. (in: firmicutes) 45000.0 2 PMID:21848698 -1.17.1.9 * candida methanolica 84000.0 4 PMID:2737206 -1.17.1.9 * citrobacter sp. 150000.0 3 PMID:24751436 -1.17.1.9 * clostridium carboxidivorans 80700.0 1 PMID:23144135 -1.17.1.9 * cupriavidus necator 197000.0 6 PMID:26553877;PMID:8335630 -1.17.1.9 * cupriavidus oxalaticus 315000.0 8 PMID:4405083;PMID:631130 -1.17.1.9 * gelatoporia subvermispora 84000.0 4 PMID:18177307;PMID:18646819;PMID:2737206 -1.17.1.9 * glycine soja 47000.0 1 PMID:16663314;PMID:6808927 -1.17.1.9 * komagataella pastoris 94000.0 4 PMID:16663314;PMID:227687;PMID:4054127;PMID:4372234;PMID:6808927 -1.17.1.9 * lathyrus oleraceus 82300.0 5 PMID:227687;PMID:4054127;PMID:4372234;PMID:574372 -1.17.1.9 * methylobacterium sp. 75000.0 1 PMID:9020054 -1.17.1.9 * methylorubrum extorquens 170000.0 3 PMID:12605683 -1.17.1.9 * methylosinus trichosporium 315000.0 4 PMID:2376564 -1.17.1.9 * methylotrophic bacterium 70000.0 2 PMID:227687;PMID:4054127;PMID:4372234 -1.17.1.9 * moraxella sp. 98000.0 2 PMID:3384805 -1.17.1.9 * ogataea angusta 78000.0 3 PMID:23715855 -1.17.1.9 * paracoccus sp. 12-a 43757.0 1 PMID:11999398 -1.17.1.9 * pseudomonas sp. 280000.0 3 PMID:18646819;PMID:2777065 -1.17.1.9 * rhodobacter capsulatus 340000.0 7 PMID:24034888;PMID:25514355;PMID:27444330 -1.17.1.9 * thermochaetoides thermophila 91200.0 2 PMID:32557118 -1.17.1.9 * thiobacillus sp. 45000.0 1 PMID:25061666 -1.17.1.9 * vigna umbellata 44000.0 1 PMID:27021188 -1.17.2.1 * pseudomonas putida 130000.0 6 PMID:18678916;PMID:19118407 -1.17.2.2 * pseudomonas sp. 74000.0 7 PMID:12119046;PMID:12686118;PMID:1656935 -1.17.3.1 * ricinus communis 310000.0 1 * -1.17.3.2 * acinetobacter calcoaceticus 190000.0 1 PMID:30926462 -1.17.3.2 * arthrobacter sp. 146000.0 4 PMID:22954965;PMID:681279 -1.17.3.2 * blastobotrys adeninivorans 360000.0 2 PMID:23773263 -1.17.3.2 * bos taurus 303000.0 9 PMID:10392571;PMID:1180567;PMID:19388706;PMID:21110814;PMID:2350174;PMID:29207340;PMID:3010873;PMID:34361656;PMID:718940 -1.17.3.2 * enterobacter cloacae 128000.0 2 * -1.17.3.2 * gallus gallus 120000.0 1 * -1.17.3.2 * homo sapiens 310000.0 4 PMID:1180567;PMID:2350174;PMID:29207340;PMID:3010873;PMID:34361656 -1.17.3.2 * mus musculus 300000.0 2 PMID:1180567;PMID:2350174;PMID:3010873 -1.17.3.2 * oryctolagus cuniculus 280000.0 3 PMID:235293 -1.17.3.3 * neobacillus niacini 140000.0 4 * -1.17.3.4 * pseudomonas putida 59000.0 4 PMID:4041238 -1.17.3.5 * sinomonas cyclohexanicum 137000.0 1 PMID:34583900 -1.17.4.1 * bacillus anthracis 79800.0 1 PMID:21832039 -1.17.4.1 * bacillus subtilis 82700.0 3 PMID:24401092 -1.17.4.1 * bos taurus 84000.0 4 PMID:7030344 -1.17.4.1 * clostridium botulinum 340000.0 1 PMID:32883811 -1.17.4.1 * corynebacterium ammoniagenes 160000.0 3 PMID:9468481 -1.17.4.1 * corynebacterium glutamicum 34000.0 1 PMID:19707921 -1.17.4.1 * escherichia coli 90000.0 5 PMID:4578086 -1.17.4.1 * herpes simplex virus 136000.0 2 PMID:2835765 -1.17.4.1 * homo sapiens 160000.0 3 PMID:17351390 -1.17.4.1 * human gammaherpesvirus 8 31000.0 1 PMID:20516613 -1.17.4.1 * kitasatospora aureofaciens 125900.0 2 PMID:8829608 -1.17.4.1 * leeuwenhoekiella blandensis 465000.0 2 PMID:29388911 -1.17.4.1 * plasmodium falciparum 250000.0 4 PMID:15769467 -1.17.4.1 * pseudomonas aeruginosa 428000.0 3 PMID:16829681;PMID:27133024 -1.17.4.1 * rattus norvegicus 75000.0 4 PMID:7049335 -1.17.4.1 * salmonella enterica subsp. enterica serovar typhimurium 70000.0 2 PMID:7809142 -1.17.4.1 * tequatrovirus t4 85000.0 4 PMID:4344645;PMID:6343369 -1.17.4.1 * tetradesmus obliquus 90000.0 2 * -1.17.4.2 * anabaena sp. 72000.0 2 PMID:6772640 -1.17.4.2 * deinococcus radiodurans 107000.0 1 PMID:9391052 -1.17.4.2 * escherichia coli 278000.0 2 PMID:4210502;PMID:6772640 -1.17.4.2 * euglena gracilis 440000.0 3 PMID:4210502 -1.17.4.2 * lactobacillus leichmannii 110000.0 11 PMID:10431931;PMID:4811061;PMID:5924645;PMID:7918494 -1.17.4.2 * pyrococcus furiosus 90000.0 1 * -1.17.4.2 * thermoplasma acidophilum 100000.0 1 PMID:8990160 -1.17.4.2 * thermotoga maritima 90000.0 1 PMID:9391052 -1.17.4.2 * thermus sp. 80000.0 1 PMID:4542513 -1.17.4.4 * homo sapiens 21000.0 2 PMID:16677080;PMID:17164330 -1.17.4.4 * rattus norvegicus 18000.0 1 PMID:18374192 -1.17.4.5 * bos taurus 25000.0 2 PMID:3857611 -1.17.5.1 * thauera aromatica 280000.0 4 PMID:10336636 -1.17.5.2 * pseudomonas sp. 158000.0 7 PMID:17981969;PMID:22609920 -1.17.5.3 * escherichia coli 590000.0 4 PMID:1099093 -1.17.5.3 * wolinella succinogenes 110000.0 3 PMID:6639943 -1.17.7.2 * arabidopsis thaliana 195000.0 1 PMID:27072131 -1.17.7.3 * escherichia coli 84000.0 2 PMID:12434382;PMID:16268586 -1.17.7.4 * babesia bovis 48000.0 1 PMID:22057350 -1.17.7.4 * burkholderia glumae 51330.0 2 * -1.17.7.4 * escherichia coli 72000.0 4 PMID:11818558;PMID:12706830;PMID:15469281 -1.17.7.4 * salvia miltiorrhiza f. alba 51860.0 1 PMID:23770591 -1.17.9.1 * pseudomonas putida 136000.0 22 PMID:15147198;PMID:15301551;PMID:15643899;PMID:15723539;PMID:3460061;PMID:3790500;PMID:588247;PMID:743215 -1.17.98.3 * methanobacterium formicicum 288000.0 4 PMID:3944055;PMID:7061389 -1.17.98.4 * escherichia coli 80000.0 2 PMID:2211698;PMID:8626495 -1.17.98.4 * methanococcus vannielii 105000.0 1 PMID:7451465 -1.17.98.4 * thermococcus onnurineus 488000.0 1 PMID:35660788 -1.17.98.5 * acetobacterium woodii 3500000.0 3 PMID:24337298;PMID:26833643 -1.17.98.5 * thermoanaerobacter kivui 1773000.0 1 PMID:30186365 -1.17.99.10 * sterolibacterium denitrificans 167000.0 2 PMID:29921665 -1.17.99.2 * aromatoleum aromaticum 155000.0 2 PMID:25635950;PMID:26960184 -1.17.99.2 * azoarcus sp. 545000.0 13 PMID:11294876;PMID:11443088 -1.17.99.3 * rattus norvegicus 175000.0 5 PMID:2156865;PMID:7998933 -1.17.99.8 * castellaniella defragrans 152000.0 1 PMID:29716998 -1.17.99.9 * aeropyrum pernix 17000.0 1 PMID:16989823 -1.17.99.9 * aquifex aeolicus 150000.0 1 PMID:32605991 -1.17.99.9 * geobacillus stearothermophilus 28000.0 1 PMID:10052128 -1.18.1.1 * alcanivorax borkumensis 41000.0 1 PMID:21714118 -1.18.1.1 * clostridium acetobutylicum 41000.0 2 PMID:526302 -1.18.1.1 * ectopseudomonas oleovorans 55300.0 2 PMID:4335861 -1.18.1.1 * megalodesulfovibrio gigas 32000.0 2 PMID:8375383 -1.18.1.2 * anabaena cylindrica 70000.0 2 PMID:6766886;PMID:6783100 -1.18.1.2 * anabaena sp. 80000.0 4 PMID:3089056;PMID:8917622;PMID:9287153 -1.18.1.2 * arabidopsis thaliana 35000.0 2 PMID:17335513 -1.18.1.2 * bacillus subtilis 97000.0 4 PMID:15252706;PMID:24529496;PMID:25698407 -1.18.1.2 * bumilleriopsis filiformis 80000.0 2 PMID:158901;PMID:36038 -1.18.1.2 * capsicum annuum 40410.0 2 PMID:11053431 -1.18.1.2 * chlamydomonas reinhardtii 42000.0 4 * -1.18.1.2 * chlorobaculum tepidum 91000.0 3 PMID:18323604;PMID:29119426 -1.18.1.2 * cyanidium caldarium 34000.0 2 PMID:17828614;PMID:7469423 -1.18.1.2 * escherichia coli 28981.0 2 PMID:20407804 -1.18.1.2 * euglena gracilis 15000.0 1 PMID:3120772 -1.18.1.2 * hydrogenobacter thermophilus 30000.0 2 PMID:19552713 -1.18.1.2 * lathyrus oleraceus 60000.0 3 PMID:18253859;PMID:4083475;PMID:8286947;PMID:8286951 -1.18.1.2 * limnospira platensis 90000.0 6 PMID:17828614;PMID:500589 -1.18.1.2 * mycobacterium tuberculosis 53000.0 2 PMID:12071965 -1.18.1.2 * nostoc sp. 31500.0 1 PMID:105951 -1.18.1.2 * ovis aries 52300.0 2 PMID:2364676 -1.18.1.2 * paenibacillus polymyxa 60000.0 1 PMID:21221720;PMID:4147648 -1.18.1.2 * phaseolus vulgaris 72000.0 3 PMID:2105079 -1.18.1.2 * plasmodium falciparum 37270.0 2 PMID:17258767 -1.18.1.2 * pseudomonas putida 35000.0 4 PMID:18062229;PMID:19122206 -1.18.1.2 * pyrococcus furiosus 88951.0 1 PMID:28705933 -1.18.1.2 * raphanus sativus 35000.0 1 PMID:16667598 -1.18.1.2 * rattus norvegicus 52000.0 3 PMID:10525147;PMID:687632 -1.18.1.2 * rhodobacter capsulatus 30000.0 1 PMID:14572660 -1.18.1.2 * spinacia oleracea 117000.0 18 PMID:1230015;PMID:15271510;PMID:17828614;PMID:18253859;PMID:21114674;PMID:2186705;PMID:2195029;PMID:2202597;PMID:3745183;PMID:4083475;PMID:6766886;PMID:6783100;PMID:7469423;PMID:8286947;PMID:922016 -1.18.1.2 * spirulina sp. 34140.0 1 PMID:6430889 -1.18.1.2 * sulfurisphaera tokodaii 36600.0 1 PMID:24292509 -1.18.1.2 * sus scrofa 51500.0 2 PMID:3745205 -1.18.1.2 * synechococcus elongatus 78000.0 4 PMID:12040095 -1.18.1.2 * synechocystis sp. 60000.0 6 PMID:15894798;PMID:17116880;PMID:21221720;PMID:4147648 -1.18.1.2 * toxoplasma gondii 46300.0 5 PMID:16533038;PMID:18175327;PMID:19237441 -1.18.1.2 * trichormus variabilis 52000.0 3 PMID:2461678;PMID:3124746 -1.18.1.2 * triticum aestivum 36000.0 6 PMID:18253859 -1.18.1.3 * methylosinus trichosporium ob3b 36000.0 1 PMID:2768195 -1.18.1.3 * mycobacterium sp. 50000.0 2 PMID:16079338 -1.18.1.3 * mycobacterium tuberculosis 69000.0 2 PMID:15863094 -1.18.1.3 * novosphingobium sp. 39800.0 1 PMID:20516607 -1.18.1.3 * pseudomonas chlororaphis subsp. aureofaciens 39000.0 1 * -1.18.1.3 * pseudomonas putida 46500.0 3 PMID:1327782;PMID:7204373 -1.18.1.3 * pseudomonas sp. 43600.0 5 PMID:2294092;PMID:9683647 -1.18.1.4 * chlorobaculum tepidum 91800.0 1 PMID:33051772 -1.18.1.4 * entamoeba histolytica 41000.0 1 PMID:25725270 -1.18.1.4 * pyrococcus furiosus 51000.0 5 PMID:10464233;PMID:11398485;PMID:15746356 -1.18.1.6 * bos taurus 54300.0 11 PMID:10369776;PMID:18399988;PMID:2016263;PMID:235468;PMID:2503499;PMID:4144106;PMID:7130144;PMID:7811729;PMID:986153 -1.18.1.6 * homo sapiens 52000.0 1 PMID:21621619 -1.18.1.6 * mycobacterium tuberculosis 49357.0 1 PMID:12614197 -1.18.1.6 * sus scrofa 53000.0 4 PMID:913589 -1.18.1.7 * pseudomonas putida 37104.0 4 PMID:2294092;PMID:2294093 -1.18.6.1 * allochromatium vinosum 270000.0 2 PMID:183600 -1.18.6.1 * anabaena cylindrica 220000.0 1 PMID:111934 -1.18.6.1 * azotobacter chroococcum 270000.0 7 PMID:173545;PMID:183600;PMID:8286368 -1.18.6.1 * azotobacter vinelandii 270000.0 14 PMID:14996831;PMID:164247;PMID:173545;PMID:183600;PMID:3913292;PMID:6383195;PMID:6799495;PMID:8286368;PMID:8784188;PMID:9860849 -1.18.6.1 * bradyrhizobium japonicum 270000.0 5 PMID:183600 -1.18.6.1 * bradyrhizobium lupini 270000.0 4 PMID:183600;PMID:4215454 -1.18.6.1 * clostridium pasteurianum 270000.0 15 PMID:164247;PMID:183600;PMID:4369192;PMID:6383195;PMID:8286368 -1.18.6.1 * cyanobacterium sp. 216000.0 2 PMID:8286368 -1.18.6.1 * klebsiella pneumoniae 270000.0 10 PMID:111934;PMID:164247;PMID:183600;PMID:6383195 -1.18.6.1 * rhizobium sp. 219000.0 3 * -1.18.6.1 * rhodobacter capsulatus 250000.0 11 PMID:12667075;PMID:3913292;PMID:6799495;PMID:8784188;PMID:9108249;PMID:9860849 -1.18.6.1 * rhodospirillum rubrum 230000.0 2 PMID:3913292;PMID:6799495;PMID:8784188;PMID:9860849 -1.18.6.2 * azotobacter chroococcum 210000.0 2 PMID:2821997;PMID:2851977 -1.18.6.2 * azotobacter vinelandii 235300.0 2 PMID:27928630 -1.19.1.1 * bacillus cereus 110000.0 2 PMID:24915092 -1.19.1.1 * bacillus subtilis 40000.0 1 PMID:25698407 -1.19.1.1 * escherichia coli 27648.0 1 PMID:9839946 -1.19.1.1 * rhodobacter capsulatus 30138.0 2 PMID:14572660 -1.19.6.1 * azotobacter vinelandii 230000.0 1 PMID:9860849 -1.2.1.10 * acinetobacter sp. hbs-2 57000.0 1 * -1.2.1.10 * chlamydomonas reinhardtii 440000.0 1 PMID:28007962 -1.2.1.10 * citrobacter sp. s-77 400000.0 1 PMID:26216639 -1.2.1.10 * clostridium beijerinckii 100000.0 2 PMID:2275527 -1.2.1.10 * clostridium kluyveri 290000.0 1 PMID:7458347 -1.2.1.10 * escherichia coli 900000.0 7 PMID:2015910;PMID:23237860;PMID:6374020 -1.2.1.10 * giardia duodenalis 95000.0 1 PMID:9633598 -1.2.1.10 * leuconostoc mesenteroides 96600.0 1 PMID:15928858 -1.2.1.10 * polytomella sp. pringsheim 198.80 88000.0 2 PMID:14756315 -1.2.1.10 * propionibacterium freudenreichii 188000.0 2 * -1.2.1.10 * pseudomonas sp. 148000.0 4 PMID:12764229;PMID:8419288 -1.2.1.10 * thermoanaerobacter ethanolicus 360000.0 2 PMID:8068002 -1.2.1.10 * thermoanaerobacter sp. 555000.0 6 PMID:26253677 -1.2.1.100 * mesorhizobium loti 59100.0 1 PMID:19218190 -1.2.1.100 * pseudomonas sp. ma-1 65000.0 1 PMID:3533936 -1.2.1.102 * arthrobacter sp. cr-7 242000.0 1 PMID:3533936 -1.2.1.104 * ascaris sp. 42000.0 2 PMID:3651502 -1.2.1.104 * azotobacter vinelandii 190000.0 2 PMID:6468378 -1.2.1.104 * bacillus subtilis 37000.0 1 * -1.2.1.104 * bos taurus 154000.0 8 PMID:7273851 -1.2.1.104 * escherichia coli 206000.0 4 PMID:383998;PMID:386335;PMID:3905803;PMID:6373436 -1.2.1.104 * geobacillus stearothermophilus 42000.0 2 PMID:9655930 -1.2.1.104 * homo sapiens 2000000.0 2 PMID:33370314 -1.2.1.104 * pigeon 42000.0 2 PMID:3812084 -1.2.1.104 * pseudomonas aeruginosa 92500.0 1 PMID:6785386 -1.2.1.104 * rattus norvegicus 41000.0 2 PMID:6412756 -1.2.1.104 * saccharomyces cerevisiae 2000000.0 5 PMID:33370314;PMID:6751874;PMID:7030741 -1.2.1.104 * saccharomyces pastorianus 100000.0 3 PMID:4611884;PMID:6751874;PMID:7030741 -1.2.1.104 * thermus thermophilus 100000.0 1 PMID:9655930 -1.2.1.104 * zea mays 43000.0 2 PMID:9536062 -1.2.1.104 * zymomonas mobilis 56000.0 2 PMID:9515924 -1.2.1.105 * azotobacter vinelandii 103000.0 1 PMID:10848975 -1.2.1.105 * escherichia coli 190000.0 1 PMID:4588679 -1.2.1.105 * homo sapiens 52000.0 1 PMID:15466852 -1.2.1.105 * komagataeibacter xylinus 360000.0 2 PMID:6896181 -1.2.1.105 * neurospora crassa 52900.0 1 PMID:2521564 -1.2.1.105 * rattus norvegicus 50000.0 1 PMID:18081316 -1.2.1.105 * solanum tuberosum 105000.0 1 PMID:10745006 -1.2.1.107 * lathyrus oleraceus 145000.0 1 PMID:7144576 -1.2.1.107 * spinacia oleracea 150000.0 1 * -1.2.1.107 * sus scrofa 145000.0 1 PMID:7144576 -1.2.1.11 * amycolatopsis mediterranei u32 37000.0 1 PMID:10952005 -1.2.1.11 * arabidopsis thaliana 36000.0 1 PMID:11812229 -1.2.1.11 * cryptococcus deneoformans 160000.0 1 PMID:26527262 -1.2.1.11 * escherichia coli 77500.0 5 PMID:2868399;PMID:6102909 -1.2.1.11 * mycobacterium tuberculosis 75000.0 5 PMID:15752328;PMID:18323599 -1.2.1.11 * paracoccus versutus 44000.0 1 * -1.2.1.11 * saccharomyces cerevisiae 156000.0 4 PMID:2570346;PMID:4145650;PMID:4383930 -1.2.1.11 * salmonella enterica 39000.0 1 PMID:21369577 -1.2.1.11 * streptococcus mutans 45000.0 1 PMID:6125561 -1.2.1.12 * antheraea mylitta 37600.0 1 PMID:19724138 -1.2.1.12 * apis mellifera 140000.0 1 PMID:165383 -1.2.1.12 * arabidopsis thaliana 120000.0 3 PMID:11755196;PMID:16258009;PMID:16551514;PMID:20727989;PMID:22607208 -1.2.1.12 * ascaris suum 40000.0 1 PMID:11755196;PMID:20727989;PMID:22607208 -1.2.1.12 * bacillus anthracis 40000.0 1 PMID:11755196;PMID:20727989;PMID:22607208 -1.2.1.12 * bacillus cereus 36000.0 1 PMID:19430704;PMID:229773;PMID:236448;PMID:4632199;PMID:7408867;PMID:911794 -1.2.1.12 * bos taurus 150000.0 4 PMID:21205411;PMID:2376595;PMID:25176140;PMID:2713422;PMID:3026343;PMID:4313838;PMID:6755173 -1.2.1.12 * caenorhabditis elegans 131000.0 2 PMID:6389551 -1.2.1.12 * camelus dromedarius 146000.0 3 PMID:17277890 -1.2.1.12 * cyanophora paradoxa 142000.0 2 PMID:19430704;PMID:229773;PMID:236448;PMID:2713422;PMID:4313838;PMID:4632199;PMID:7408867;PMID:911794 -1.2.1.12 * dissostichus mawsoni 142000.0 1 PMID:5499623 -1.2.1.12 * drosophila melanogaster 37000.0 2 PMID:2984203 -1.2.1.12 * dunaliella salina 40270.0 1 PMID:19123030 -1.2.1.12 * entamoeba histolytica 37000.0 1 PMID:17586498 -1.2.1.12 * escherichia coli 36000.0 2 PMID:17449317;PMID:4326214 -1.2.1.12 * euglena gracilis 140500.0 4 PMID:17874335;PMID:2271518;PMID:22903596;PMID:6250837;PMID:960 -1.2.1.12 * fasciola gigantica 145000.0 1 PMID:30706165 -1.2.1.12 * fasciola hepatica 113000.0 1 PMID:24566472 -1.2.1.12 * geobacillus stearothermophilus 148700.0 2 PMID:19430704;PMID:229773;PMID:236448;PMID:4632199;PMID:7408867;PMID:911794 -1.2.1.12 * glycine max 147000.0 2 PMID:17874335;PMID:2271518;PMID:22903596;PMID:6250837;PMID:960 -1.2.1.12 * haemonchus contortus 150000.0 5 PMID:21205411;PMID:2376595;PMID:23927077 -1.2.1.12 * haloarcula vallismortis 190000.0 4 PMID:8352651 -1.2.1.12 * heyndrickxia coagulans 146800.0 2 PMID:19430704;PMID:229773;PMID:236448;PMID:4632199;PMID:7408867;PMID:911794 -1.2.1.12 * homo sapiens 150000.0 25 PMID:15520;PMID:15716040;PMID:15985219;PMID:16474839;PMID:17613523;PMID:17669159;PMID:17989880;PMID:18194256;PMID:18298375;PMID:19430704;PMID:21269272;PMID:21314614;PMID:229773;PMID:236448;PMID:25091199;PMID:25936797;PMID:3370218;PMID:4632199;PMID:7144574;PMID:7408867;PMID:911794 -1.2.1.12 * kluyveromyces marxianus 130000.0 1 PMID:16963457 -1.2.1.12 * lactiplantibacillus plantarum 40000.0 1 PMID:15985219;PMID:18194256 -1.2.1.12 * lathyrus oleraceus 145000.0 1 * -1.2.1.12 * lentinus polychrous 36200.0 1 * -1.2.1.12 * mus musculus 150000.0 3 PMID:17874335;PMID:18850593;PMID:2271518;PMID:22903596;PMID:6250837;PMID:718958;PMID:960 -1.2.1.12 * neisseria meningitidis 209200.0 5 PMID:17619949 -1.2.1.12 * nitrosomonas europaea 75000.0 1 PMID:30690134 -1.2.1.12 * oplegnathus fasciatus 35990.0 2 PMID:18692141 -1.2.1.12 * oryctolagus cuniculus 144000.0 8 PMID:15985219;PMID:16258009;PMID:16444750;PMID:16551514;PMID:17613523;PMID:18194256;PMID:18850593;PMID:21314614;PMID:229773;PMID:718958 -1.2.1.12 * oryza sativa 37000.0 1 PMID:17874335;PMID:2271518;PMID:22903596;PMID:6250837;PMID:960 -1.2.1.12 * paracoccidioides brasiliensis 39000.0 1 PMID:16368993 -1.2.1.12 * pichia kudriavzevii 36000.0 1 PMID:223420642 -1.2.1.12 * pinus sylvestris 36000.0 1 PMID:2043282;PMID:7811973 -1.2.1.12 * plasmodium falciparum 161984.0 5 PMID:16131754;PMID:16345073;PMID:26341815 -1.2.1.12 * pleurodeles waltl 37000.0 1 PMID:17874335;PMID:2271518;PMID:22903596;PMID:6250837;PMID:960 -1.2.1.12 * priestia megaterium 35914.0 1 PMID:2123030 -1.2.1.12 * pseudomonas aeruginosa 315000.0 1 PMID:3128638 -1.2.1.12 * pseudomonas sp. phi9 36100.0 1 PMID:18759222 -1.2.1.12 * rattus norvegicus 37000.0 1 PMID:16170200 -1.2.1.12 * saccharolobus solfataricus 155000.0 2 PMID:7663406 -1.2.1.12 * saccharomyces cerevisiae 180000.0 5 PMID:17874335;PMID:2043282;PMID:2271518;PMID:22903596;PMID:2713422;PMID:6250837;PMID:6755173;PMID:7811973;PMID:960 -1.2.1.12 * sardina pilchardus 38500.0 2 PMID:18064387 -1.2.1.12 * spinacia oleracea 180000.0 6 PMID:17140414;PMID:202324 -1.2.1.12 * staphylococcus aureus 37600.0 2 PMID:18931438 -1.2.1.12 * starmerella bombicola 35673.0 1 PMID:18594888 -1.2.1.12 * streptococcus agalactiae 160000.0 1 PMID:27875551 -1.2.1.12 * streptococcus pneumoniae 38000.0 1 PMID:24938797 -1.2.1.12 * streptomyces arenae 290000.0 4 PMID:6822480 -1.2.1.12 * sus scrofa 148000.0 4 PMID:15520;PMID:21269272;PMID:2271518;PMID:3830153;PMID:7144576 -1.2.1.12 * synechococcus elongatus 36830.0 1 PMID:22153507 -1.2.1.12 * tetrahymena pyriformis 36000.0 1 PMID:17669159;PMID:17989880 -1.2.1.12 * thermotoga maritima 148000.0 2 PMID:15520;PMID:17874335;PMID:2271518;PMID:22903596;PMID:6250837;PMID:960 -1.2.1.12 * thermus aquaticus 36000.0 1 PMID:19430704;PMID:229773;PMID:236448;PMID:4632199;PMID:7408867;PMID:911794 -1.2.1.12 * thermus thermophilus 135000.0 4 PMID:6270 -1.2.1.12 * trichoderma koningii 152000.0 2 PMID:2226438 -1.2.1.12 * trypanosoma brucei 150000.0 3 PMID:3830153;PMID:7144576 -1.2.1.12 * xenopus laevis 35000.0 1 PMID:2713422;PMID:6755173 -1.2.1.12 * zymomonas mobilis 150000.0 2 PMID:25176140;PMID:3026343;PMID:3680173 -1.2.1.13 * asterionella formosa 299000.0 2 PMID:24799178 -1.2.1.13 * chlamydomonas reinhardtii 155000.0 4 PMID:12492483 -1.2.1.13 * corynebacterium glutamicum 51200.0 2 PMID:15925900 -1.2.1.13 * hordeum vulgare 39000.0 3 PMID:109446;PMID:35350 -1.2.1.13 * kluyveromyces lactis 40000.0 1 PMID:12427047 -1.2.1.13 * lathyrus oleraceus 42000.0 3 PMID:109446;PMID:35350 -1.2.1.13 * methanothermus fervidus 200000.0 2 PMID:3569291 -1.2.1.13 * onchocerca volvulus 38000.0 2 PMID:15955451 -1.2.1.13 * phaseolus vulgaris 820000.0 1 PMID:16661389 -1.2.1.13 * saccharolobus solfataricus 155000.0 9 PMID:23865479;PMID:7663406;PMID:8259927;PMID:8521845;PMID:9761871 -1.2.1.13 * sinapis alba 42000.0 4 PMID:109446;PMID:16660295;PMID:35350 -1.2.1.13 * spinacia oleracea 760000.0 21 PMID:109446;PMID:16055685;PMID:2223845;PMID:23161;PMID:35350;PMID:4396069 -1.2.1.13 * sulfurisphaera tokodaii 148000.0 3 PMID:22841742 -1.2.1.13 * thermoproteus tenax 210000.0 3 PMID:3121324 -1.2.1.16 * crocosphaera subtropica 109000.0 1 PMID:32966327 -1.2.1.16 * cupriavidus necator 49000.0 1 PMID:19648235 -1.2.1.16 * escherichia coli 200000.0 3 PMID:23296511;PMID:7011797 -1.2.1.16 * euglena gracilis 150000.0 1 PMID:4121 -1.2.1.16 * klebsiella pneumoniae 300000.0 3 PMID:2647149 -1.2.1.16 * pseudomonas putida 100000.0 6 PMID:18498778;PMID:3355840 -1.2.1.16 * saccharolobus solfataricus 51600.0 1 * -1.2.1.16 * salmonella enterica subsp. enterica serovar typhimurium 84000.0 2 PMID:23229889 -1.2.1.16 * streptococcus pyogenes 52000.0 1 PMID:22442224 -1.2.1.16 * sulfurisphaera tokodaii 180000.0 2 PMID:23748791 -1.2.1.18 * rattus norvegicus 250000.0 2 PMID:2768248 -1.2.1.19 * arthrobacter sp. 210000.0 2 PMID:12186751 -1.2.1.19 * avena sativa 55000.0 1 PMID:12579364 -1.2.1.19 * escherichia coli 202000.0 4 PMID:16023116;PMID:3129020 -1.2.1.19 * glycine max 64000.0 1 * -1.2.1.19 * lathyrus oleraceus 120000.0 2 PMID:20026072 -1.2.1.19 * pseudomonas putida 240000.0 3 * -1.2.1.19 * pseudomonas sp. 228000.0 2 PMID:4817964 -1.2.1.19 * rattus norvegicus 115000.0 4 PMID:10467734;PMID:7584606 -1.2.1.20 * pseudomonas aeruginosa pao1 53000.0 1 PMID:17388807 -1.2.1.20 * pseudomonas putida 170000.0 1 * -1.2.1.21 * escherichia coli 345000.0 3 * -1.2.1.22 * bacillus subtilis 70000.0 1 PMID:4319789 -1.2.1.22 * escherichia coli 220000.0 5 PMID:16731973;PMID:17173928;PMID:3308886;PMID:4310089 -1.2.1.22 * methanocaldococcus jannaschii 180000.0 2 PMID:16585745 -1.2.1.22 * saccharomyces cerevisiae 40000.0 1 PMID:3908097 -1.2.1.22 * scheffersomyces stipitis 55000.0 2 PMID:18793327 -1.2.1.23 * bacillus subtilis 500000.0 1 PMID:4322199 -1.2.1.23 * capra hircus 43000.0 2 PMID:7107625 -1.2.1.23 * homo sapiens 43000.0 1 PMID:2721637 -1.2.1.23 * pseudomonas putida 43000.0 2 * -1.2.1.24 * arabidopsis sp. 53000.0 1 PMID:10517851 -1.2.1.24 * aspergillus niger 160000.0 1 PMID:25757236 -1.2.1.24 * azospirillum brasilense 220000.0 2 PMID:16835232 -1.2.1.24 * ctenocephalides felis 55400.0 2 PMID:18477242 -1.2.1.24 * drosophila melanogaster 98200.0 1 PMID:18252249 -1.2.1.24 * escherichia coli 50000.0 1 PMID:17873044 -1.2.1.24 * euglena gracilis 150000.0 1 PMID:4121 -1.2.1.24 * homo sapiens 245000.0 10 PMID:16199352;PMID:20973619;PMID:2596851;PMID:3190233;PMID:656447 -1.2.1.24 * hordeum vulgare subsp. vulgare 225000.0 2 * -1.2.1.24 * klebsiella pneumoniae 52000.0 1 * -1.2.1.24 * lucilia cuprina 55400.0 2 PMID:18477242 -1.2.1.24 * lumbricus rubellus 120000.0 2 * -1.2.1.24 * mus musculus 98000.0 1 PMID:18588919 -1.2.1.24 * pseudomonas sp. 164000.0 2 PMID:4353629 -1.2.1.24 * rattus norvegicus 140000.0 4 PMID:12871571;PMID:19091 -1.2.1.24 * rhipicephalus microplus 98000.0 1 PMID:18588919 -1.2.1.24 * saccharolobus solfataricus 157000.0 3 PMID:23296511 -1.2.1.24 * solanum tuberosum 145000.0 2 PMID:2596851;PMID:656447 -1.2.1.24 * sus scrofa 160000.0 2 PMID:7408894 -1.2.1.24 * triticum turgidum subsp. durum 130000.0 1 PMID:24408099 -1.2.1.26 * acinetobacter baylyi 62000.0 1 PMID:18364348 -1.2.1.26 * azospirillum brasilense 57000.0 6 PMID:17202142 -1.2.1.26 * pseudomonas sp. 115000.0 1 PMID:6024771 -1.2.1.26 * saccharolobus solfataricus 210100.0 2 PMID:16849334 -1.2.1.27 * oryza sativa 57200.0 2 PMID:15045523;PMID:19071198 -1.2.1.27 * pseudomonas aeruginosa 132000.0 3 PMID:4314598 -1.2.1.27 * rattus norvegicus 250000.0 3 PMID:10989432;PMID:2768248 -1.2.1.27 * saccharolobus solfataricus 130000.0 3 PMID:23296511 -1.2.1.28 * acinetobacter calcoaceticus 225000.0 6 PMID:2597133;PMID:3291854;PMID:4656805;PMID:9494109 -1.2.1.28 * antirrhinum majus 232400.0 2 PMID:19292760 -1.2.1.28 * pseudomonas putida 208000.0 8 PMID:21448720;PMID:7868591 -1.2.1.28 * pseudomonas sp. 54400.0 1 * -1.2.1.29 * phanerodontia chrysosporium 54400.0 2 PMID:20175998 -1.2.1.3 * acanthopagrus schlegelii 56000.0 1 PMID:12604200 -1.2.1.3 * arabidopsis thaliana 112000.0 2 PMID:21166653 -1.2.1.3 * bacillus cereus 55600.0 1 PMID:23695569 -1.2.1.3 * bacillus licheniformis 53000.0 1 PMID:22117550 -1.2.1.3 * bos taurus 220000.0 5 PMID:2241149;PMID:627210;PMID:6651765 -1.2.1.3 * ctenopharyngodon idella 55000.0 1 PMID:11306040;PMID:23297067;PMID:8645224 -1.2.1.3 * danio rerio 56000.0 1 PMID:15703303;PMID:16411662 -1.2.1.3 * equus caballus 240000.0 4 PMID:7278684 -1.2.1.3 * escherichia coli 53000.0 1 PMID:18668238 -1.2.1.3 * euglena gracilis 160000.0 2 PMID:16441583 -1.2.1.3 * geobacillus thermodenitrificans 440000.0 4 PMID:20171064 -1.2.1.3 * geobacillus thermoleovorans 53886.0 1 PMID:19787414 -1.2.1.3 * halobacterium salinarum 53800.0 1 PMID:16396511 -1.2.1.3 * homo sapiens 245000.0 42 PMID:11306040;PMID:12616643;PMID:12941160;PMID:15703303;PMID:16411662;PMID:17673211;PMID:17974998;PMID:18196;PMID:18272654;PMID:18505683;PMID:18621017;PMID:18644979;PMID:19382905;PMID:19506075;PMID:19633610;PMID:20207735;PMID:20616185;PMID:224930;PMID:23224332;PMID:23297067;PMID:23444097;PMID:27759097;PMID:29045138;PMID:3592683;PMID:6189823;PMID:7278684;PMID:8155713;PMID:8645224 -1.2.1.3 * klebsiella pneumoniae 55000.0 2 PMID:11306040;PMID:18668238;PMID:23297067;PMID:8645224 -1.2.1.3 * lachnoclostridium phytofermentans 191300.0 1 PMID:26899032 -1.2.1.3 * mus musculus 58000.0 1 PMID:18436815 -1.2.1.3 * natronomonas pharaonis 60000.0 1 PMID:18769868 -1.2.1.3 * nocardia sp. 200000.0 2 PMID:2241149;PMID:627210 -1.2.1.3 * oryctolagus cuniculus 370000.0 4 PMID:12941160;PMID:3756202 -1.2.1.3 * oryza sativa 66000.0 2 PMID:20634950 -1.2.1.3 * ovis aries 212000.0 5 PMID:194582;PMID:223840;PMID:7278684 -1.2.1.3 * penaeus vannamei 62400.0 1 PMID:21228234 -1.2.1.3 * phanerodontia chrysosporium 55400.0 2 PMID:20175998 -1.2.1.3 * pseudomonas aeruginosa 225000.0 1 PMID:22435;PMID:6292666 -1.2.1.3 * pseudomonas putida 47430.0 2 PMID:12670968 -1.2.1.3 * rattus norvegicus 320000.0 14 PMID:10852;PMID:17480102;PMID:17607160;PMID:17673211;PMID:17974998;PMID:6480593;PMID:697851 -1.2.1.3 * rhodococcus erythropolis 54680.0 3 PMID:16944126 -1.2.1.3 * sinorhizobium meliloti 55100.0 2 PMID:21543322 -1.2.1.3 * sulfurisphaera tokodaii 200000.0 3 PMID:23224332;PMID:23444097 -1.2.1.3 * vitis quinquangularis 58340.0 1 * -1.2.1.30 * neurospora crassa 120000.0 1 PMID:4386171;PMID:4389863 -1.2.1.30 * nocadia sp. 163000.0 2 PMID:9171390 -1.2.1.30 * nocardia sp. 132400.0 2 PMID:15006821 -1.2.1.31 * candida maltosa 160000.0 1 * -1.2.1.31 * homo sapiens 222000.0 3 PMID:30184263 -1.2.1.31 * penicillium chrysogenum 171000.0 3 PMID:12509419;PMID:9790587 -1.2.1.31 * rattus norvegicus 250000.0 1 PMID:4369906 -1.2.1.31 * saccharomyces cerevisiae 180000.0 3 PMID:10320345;PMID:2499333 -1.2.1.32 * burkholderia cepacia 57000.0 3 PMID:15202565;PMID:16267312 -1.2.1.32 * comamonas sp. js765 52300.0 1 PMID:16947040 -1.2.1.32 * ectopseudomonas oleovorans 160000.0 3 PMID:9721300 -1.2.1.32 * pseudomonas putida 126000.0 3 PMID:1791759;PMID:2202600 -1.2.1.32 * pseudomonas sp. 51682.0 2 PMID:2194577;PMID:9367878 -1.2.1.36 * elephantulus edwardii 54407.0 1 PMID:12693930 -1.2.1.36 * homo sapiens 55000.0 4 PMID:12616643;PMID:17175089;PMID:18039331 -1.2.1.36 * mus musculus 55000.0 6 PMID:11983430;PMID:12754104;PMID:19671997;PMID:19766701;PMID:9705968 -1.2.1.36 * rattus norvegicus 214000.0 10 PMID:11882655;PMID:11983430;PMID:1527087;PMID:17239557;PMID:19671997;PMID:19766701;PMID:4312676;PMID:8329181;PMID:8663198;PMID:8797830;PMID:9705968 -1.2.1.36 * xenopus laevis 58000.0 1 PMID:16603817 -1.2.1.38 * escherichia coli 38000.0 1 PMID:17651682 -1.2.1.38 * neurospora crassa 93000.0 1 PMID:2987210 -1.2.1.39 * brevibacterium sp. 219000.0 2 PMID:17619188 -1.2.1.39 * escherichia coli 210700.0 5 PMID:16731973;PMID:9043126;PMID:9109378 -1.2.1.39 * pseudomonas putida 227000.0 3 PMID:18177365;PMID:28153386 -1.2.1.4 * acetobacter aceti 87000.0 5 * -1.2.1.4 * acetobacter pasteurianus 82000.0 1 * -1.2.1.4 * escherichia coli 220000.0 3 PMID:15659684 -1.2.1.4 * gluconobacter oxydans 148000.0 2 * -1.2.1.4 * mus musculus 51000.0 2 PMID:16289176;PMID:17567582 -1.2.1.4 * proteus vulgaris 130000.0 1 PMID:13839;PMID:6292665 -1.2.1.4 * pseudomonas aeruginosa 215000.0 1 PMID:22435;PMID:6292666 -1.2.1.4 * saccharomyces cerevisiae 190000.0 2 PMID:8615805 -1.2.1.41 * campylobacter jejuni 46000.0 1 PMID:8341262 -1.2.1.41 * escherichia coli 189000.0 4 PMID:6089111;PMID:7035170 -1.2.1.41 * meiothermus ruber 41980.0 1 * -1.2.1.41 * oryza sativa 79500.0 1 PMID:19071198 -1.2.1.41 * solanum lycopersicum 60000.0 1 PMID:9223347 -1.2.1.42 * acinetobacter 33000.0 1 PMID:11872467 -1.2.1.42 * acinetobacter calcoaceticus 32000.0 1 PMID:9139916 -1.2.1.42 * anas platyrhynchos 56000.0 1 PMID:7887931 -1.2.1.42 * bos taurus 95000.0 1 PMID:4343165 -1.2.1.42 * lathyrus oleraceus 58000.0 2 PMID:9126278 -1.2.1.42 * marinobacter nauticus 116000.0 1 PMID:22035211 -1.2.1.42 * simmondsia chinensis 56000.0 2 PMID:10712526 -1.2.1.44 * arabidopsis thaliana 37500.0 3 PMID:11430991;PMID:16122934 -1.2.1.44 * eucalyptus gunnii 38000.0 1 PMID:7454 -1.2.1.44 * forsythia suspensa 40000.0 1 PMID:236926 -1.2.1.44 * glycine max 38000.0 3 PMID:7042334;PMID:7454 -1.2.1.44 * isatis tinctoria 37500.0 1 PMID:20859691 -1.2.1.44 * leucaena leucocephala 38000.0 1 PMID:23541561 -1.2.1.44 * lolium perenne 37400.0 1 * -1.2.1.44 * panicum virgatum 39040.0 2 PMID:19761442 -1.2.1.44 * picea abies 38700.0 2 PMID:7042334 -1.2.1.44 * populus x canadensis 38000.0 2 PMID:6365550 -1.2.1.44 * salvia miltiorrhiza 35700.0 1 * -1.2.1.44 * solanum lycopersicum 36800.0 2 PMID:16551686 -1.2.1.44 * triticum aestivum 50000.0 3 PMID:16006242;PMID:17452751 -1.2.1.46 * arthrobacter sp. 48000.0 2 * -1.2.1.46 * bacillus subtilis 164000.0 1 PMID:28320283 -1.2.1.46 * methylococcus capsulatus 250000.0 2 PMID:10206695;PMID:7461603 -1.2.1.46 * ogataea angusta 40000.0 1 PMID:17565589 -1.2.1.46 * pseudomonas aeruginosa 150000.0 1 PMID:24125754 -1.2.1.46 * pseudomonas putida 250000.0 7 PMID:10206695;PMID:12445786;PMID:571868;PMID:7461603;PMID:8169197 -1.2.1.47 * bos taurus 160000.0 2 PMID:18175913;PMID:7356654 -1.2.1.47 * homo sapiens 223000.0 2 PMID:30914451;PMID:32717224 -1.2.1.47 * pseudomonas sp. 160000.0 4 PMID:18175913;PMID:23225139;PMID:7356654 -1.2.1.47 * rattus norvegicus 55000.0 1 PMID:10702312 -1.2.1.48 * acinetobacter sp. 232000.0 3 PMID:10919810 -1.2.1.48 * geobacillus thermoleovorans 410000.0 3 PMID:19787414 -1.2.1.48 * homo sapiens 57000.0 3 PMID:18035827;PMID:19965611;PMID:9133646 -1.2.1.48 * mus musculus 55000.0 1 PMID:19965611 -1.2.1.48 * rattus norvegicus 55000.0 1 PMID:19965611 -1.2.1.48 * staphylococcus aureus 100000.0 1 * -1.2.1.49 * capra hircus 43000.0 2 PMID:7107625 -1.2.1.49 * homo sapiens 40000.0 1 PMID:12604221 -1.2.1.49 * rattus norvegicus 50000.0 1 PMID:20958 -1.2.1.5 * bacillus cereus 216000.0 2 PMID:23695569;PMID:27107124 -1.2.1.5 * bacillus licheniformis 220000.0 3 PMID:20495892 -1.2.1.5 * bos taurus 250000.0 2 * -1.2.1.5 * cupriavidus necator 100000.0 3 PMID:11717302 -1.2.1.5 * cytophaga sp. 110000.0 2 PMID:12419301;PMID:18462753;PMID:3933572;PMID:8401311 -1.2.1.5 * equus caballus 240000.0 4 PMID:1244351;PMID:7144584 -1.2.1.5 * homo sapiens 125000.0 6 PMID:23295226;PMID:8328987 -1.2.1.5 * mus musculus 110000.0 2 PMID:12419301;PMID:18462753;PMID:3933572;PMID:8401311 -1.2.1.5 * oryza sativa 66000.0 13 PMID:19071198 -1.2.1.5 * paraburkholderia xenovorans lb400 110000.0 1 PMID:12419301;PMID:18462753;PMID:3933572;PMID:8401311 -1.2.1.5 * rattus norvegicus 240000.0 5 PMID:12419301;PMID:18462753;PMID:2802624;PMID:3355167;PMID:3933572;PMID:8401311 -1.2.1.5 * saccharomyces cerevisiae 207000.0 5 PMID:19457;PMID:6755180;PMID:9473035 -1.2.1.5 * sphingopyxis macrogoltabida 190000.0 3 PMID:15726348 -1.2.1.5 * sulfurisphaera tokodaii 200000.0 3 PMID:23224332 -1.2.1.50 * acinetobacter sp. 33000.0 2 PMID:11872467 -1.2.1.50 * anas platyrhynchos 56000.0 1 PMID:7887931 -1.2.1.50 * apis mellifera 59200.0 1 PMID:20542116 -1.2.1.50 * arabidopsis thaliana 68400.0 5 PMID:19062129 -1.2.1.50 * cryptosporidium parvum 140000.0 1 PMID:21092192 -1.2.1.50 * marinobacter nauticus 116000.0 1 PMID:22035211 -1.2.1.50 * photobacterium phosphoreum 450000.0 8 * -1.2.1.50 * simmondsia chinensis 56200.0 1 PMID:10712526 -1.2.1.51 * cryptosporidium parvum 217000.0 1 PMID:16872290 -1.2.1.51 * euglena gracilis 320000.0 8 PMID:11023353;PMID:12623066;PMID:1910287;PMID:3110154 -1.2.1.54 * pseudomonas putida 107000.0 2 * -1.2.1.54 * vicia faba 83000.0 1 PMID:16663901 -1.2.1.57 * clostridium acetobutylicum 115000.0 2 PMID:3384801 -1.2.1.58 * aromatoleum evansii 370000.0 6 PMID:9490067 -1.2.1.59 * cyanophora paradoxa 142000.0 2 PMID:9226260 -1.2.1.59 * methanothermus fervidus 200000.0 2 PMID:3569291 -1.2.1.59 * synechocystis sp. 160000.0 2 PMID:9226260 -1.2.1.60 * escherichia coli 210000.0 4 PMID:2656390;PMID:6756482 -1.2.1.60 * klebsiella pneumoniae 102000.0 2 PMID:2656390 -1.2.1.60 * pseudomonas putida 200000.0 2 * -1.2.1.61 * pseudomonas fluorescens 52400.0 1 PMID:18502868 -1.2.1.61 * pseudomonas sp. 52000.0 1 PMID:22380602 -1.2.1.61 * sphingomonas sp. 53500.0 1 PMID:21755281 -1.2.1.63 * acinetobacter sp. 158000.0 1 PMID:856571 -1.2.1.65 * alteromonas naphthalenivorans 160000.0 1 PMID:28233868 -1.2.1.65 * pseudomonas putida 125000.0 3 PMID:22232182 -1.2.1.65 * pseudomonas sp. 150000.0 1 PMID:24122667 -1.2.1.67 * amycolatopsis sp. 54000.0 1 PMID:23064333 -1.2.1.67 * burkholderia cepacia 110000.0 2 PMID:20002191 -1.2.1.67 * candida dubliniensis 210000.0 1 * -1.2.1.67 * corynebacterium glutamicum 199200.0 4 PMID:25622822 -1.2.1.67 * micrococcus sp. 250000.0 2 PMID:20002191 -1.2.1.67 * pseudomonas fluorescens 55000.0 1 * -1.2.1.67 * sphingobium sp. syk-6 220000.0 2 PMID:28294121 -1.2.1.67 * sphingomonas paucimobilis 50301.0 1 PMID:17928721 -1.2.1.67 * streptomyces sp. nl15-2k 214000.0 1 PMID:30355315 -1.2.1.68 * pseudomonas sp. 86000.0 2 PMID:9721273 -1.2.1.69 * streptantibioticus cattleyicolor 200000.0 2 PMID:11571203 -1.2.1.7 * acinetobacter baylyi 116000.0 2 * -1.2.1.7 * pseudomonas fluorescens 200000.0 1 PMID:4383635 -1.2.1.7 * pseudomonas putida 122000.0 2 * -1.2.1.70 * acidithiobacillus ferrooxidans 148000.0 4 PMID:21219871 -1.2.1.70 * chlamydomonas reinhardtii 130000.0 6 PMID:15890644;PMID:16158240;PMID:2303495 -1.2.1.70 * escherichia coli 180000.0 3 PMID:12370189 -1.2.1.70 * hordeum vulgare 270000.0 4 PMID:7957167;PMID:8799193 -1.2.1.70 * methanopyrus kandleri 190000.0 2 PMID:10521455 -1.2.1.70 * prosthecochloris vibrioformis 49000.0 1 PMID:15968053 -1.2.1.70 * synechocystis sp. 350000.0 2 PMID:1903397 -1.2.1.72 * escherichia coli 132000.0 3 PMID:7751290;PMID:9182530 -1.2.1.73 * neptuniibacter caesariensis 196500.0 4 PMID:18506422 -1.2.1.75 * chloroflexus aurantiacus 300000.0 2 PMID:11948153 -1.2.1.75 * erythrobacter dokdonensis 265000.0 1 PMID:31814251 -1.2.1.75 * metallosphaera sedula 150000.0 2 PMID:17041055 -1.2.1.75 * sulfurisphaera tokodaii 160000.0 5 PMID:17041055 -1.2.1.76 * clostridium kluyveri 115000.0 2 PMID:8444151 -1.2.1.77 * aromatoleum evansii 54000.0 1 PMID:16585753;PMID:20452977 -1.2.1.78 * alcaligenes faecalis 158000.0 2 * -1.2.1.78 * nocardioides sp. 205000.0 2 PMID:9335300 -1.2.1.79 * acinetobacter baumannii 208000.0 1 PMID:29734522 -1.2.1.79 * cupriavidus necator 51000.0 2 PMID:10564790 -1.2.1.79 * escherichia coli 60000.0 1 PMID:2254272 -1.2.1.79 * klebsiella pneumoniae 300000.0 1 PMID:2647149 -1.2.1.79 * nostoc sp. pcc 7120 = fachb-418 85000.0 1 PMID:29242124 -1.2.1.79 * pseudomonas putida 200000.0 1 PMID:3355840 -1.2.1.79 * saccharolobus solfataricus 114000.0 3 PMID:23296511 -1.2.1.8 * amaranthus sp. 125000.0 3 PMID:11467859 -1.2.1.8 * ammopiptanthus nanus 76000.0 1 PMID:25046139 -1.2.1.8 * avena sativa 120000.0 2 PMID:12736784;PMID:9973357 -1.2.1.8 * cylindrocarpon didymum 220000.0 2 * -1.2.1.8 * escherichia coli 250000.0 4 PMID:12467448;PMID:2194570 -1.2.1.8 * homo sapiens 230000.0 2 PMID:10505788;PMID:25992309 -1.2.1.8 * ipomoea batatas 54800.0 1 * -1.2.1.8 * jatropha curcas 80000.0 1 * -1.2.1.8 * leymus chinensis 56780.0 2 PMID:10505788;PMID:25992309 -1.2.1.8 * oryza sativa 55000.0 4 PMID:18599581;PMID:19071198;PMID:19850038 -1.2.1.8 * penaeus vannamei 54150.0 1 PMID:28212821 -1.2.1.8 * pseudomonas aeruginosa 145000.0 5 PMID:12736784;PMID:16315011;PMID:9973357 -1.2.1.8 * rattus norvegicus 494000.0 4 PMID:10505788;PMID:11306043 -1.2.1.8 * spinacia oleracea 120000.0 9 PMID:2320587;PMID:2712575;PMID:3667561 -1.2.1.8 * staphylococcus aureus 215000.0 2 PMID:25945581 -1.2.1.8 * sus scrofa 688000.0 5 PMID:10329454;PMID:17977510;PMID:32881113;PMID:9734333 -1.2.1.8 * zoysia tenuifolia 55500.0 9 PMID:16255165 -1.2.1.81 * cupriavidus necator 115000.0 2 PMID:20693281 -1.2.1.84 * simmondsia chinensis 56000.0 2 PMID:10712526 -1.2.1.84 * triticum aestivum 58400.0 1 PMID:25468933 -1.2.1.85 * paenibacillus sp. 58000.0 2 PMID:19717587 -1.2.1.85 * pseudomonas putida 184000.0 1 PMID:26032336 -1.2.1.86 * castellaniella defragrans 53000.0 1 PMID:22286981 -1.2.1.86 * persicaria minor 110000.0 2 * -1.2.1.87 * paraburkholderia xenovorans 140000.0 3 PMID:19476337 -1.2.1.87 * thermus thermophilus 152000.0 7 PMID:22316175 -1.2.1.88 * bacillus licheniformis 119000.0 1 PMID:23747974 -1.2.1.88 * escherichia coli 293000.0 2 PMID:1618807 -1.2.1.88 * halalkalibacterium halodurans 119000.0 1 PMID:23747974 -1.2.1.88 * homo sapiens 142000.0 3 PMID:2211729;PMID:8621661 -1.2.1.88 * hyalomma dromedarii 60000.0 4 PMID:9418013 -1.2.1.88 * lysinibacillus sphaericus 100000.0 2 * -1.2.1.88 * oryza sativa 259000.0 4 PMID:19071198;PMID:26300893 -1.2.1.88 * rattus norvegicus 115000.0 2 PMID:2211729 -1.2.1.88 * salmonella enterica subsp. enterica serovar typhimurium 132000.0 2 PMID:6270100 -1.2.1.88 * solanum tuberosum 240000.0 2 PMID:12223682 -1.2.1.88 * streptomyces coelicolor 305000.0 2 * -1.2.1.88 * trypanosoma cruzi 714900.0 5 PMID:25623067 -1.2.1.89 * picrophilus oshimae 115000.0 3 PMID:16458304 -1.2.1.89 * thermoplasma acidophilum 215000.0 7 PMID:16458304;PMID:16566751;PMID:24034429 -1.2.1.9 * bacillus cereus 46000.0 1 PMID:16562377 -1.2.1.9 * bacillus licheniformis 52000.0 1 PMID:16562377 -1.2.1.9 * bacillus thuringiensis 47000.0 1 PMID:16562377 -1.2.1.9 * beta vulgaris 200000.0 2 PMID:220918;PMID:3341766;PMID:4405240 -1.2.1.9 * chlamydomonas reinhardtii 200000.0 1 PMID:220918;PMID:3341766;PMID:4405240 -1.2.1.9 * clostridioides difficile 55000.0 1 PMID:16562377 -1.2.1.9 * clostridium acetobutylicum 204000.0 3 PMID:12182834;PMID:16562377 -1.2.1.9 * clostridium perfringens 48000.0 1 PMID:16562377 -1.2.1.9 * clostridium sporogenes 53000.0 1 PMID:16562377 -1.2.1.9 * hevea brasiliensis 200000.0 1 PMID:220918;PMID:3341766;PMID:4405240 -1.2.1.9 * oryza sativa 53400.0 1 PMID:19071198 -1.2.1.9 * saccharolobus solfataricus 230000.0 13 PMID:17549431;PMID:21736643;PMID:24491524 -1.2.1.9 * spinacia oleracea 760000.0 6 PMID:16055685;PMID:220918;PMID:3341766;PMID:4405240 -1.2.1.9 * streptococcus agalactiae 52000.0 1 PMID:16562377 -1.2.1.9 * streptococcus equinus 51100.0 1 PMID:16553827 -1.2.1.9 * streptococcus mutans 350000.0 1 PMID:33184 -1.2.1.9 * streptococcus pyogenes 224000.0 3 PMID:12841648;PMID:16562377;PMID:24491524 -1.2.1.9 * streptococcus sp. 53000.0 1 PMID:16562377 -1.2.1.9 * sulfurisphaera tokodaii 227000.0 8 PMID:12841648;PMID:22841742;PMID:24491524 -1.2.1.9 * synechococcus sp. 160000.0 2 PMID:8687418 -1.2.1.9 * thermococcus kodakarensis 230000.0 2 PMID:21736643;PMID:24491524 -1.2.1.9 * triticum aestivum 240000.0 1 PMID:12387887 -1.2.1.90 * thermoproteus tenax 220000.0 2 PMID:9497334 -1.2.1.91 * escherichia coli 73045.0 1 PMID:9748275 -1.2.1.94 * persicaria minor 70000.0 1 PMID:27560927 -1.2.1.95 * candida albicans 150000.0 1 PMID:11717270 -1.2.1.95 * gelatoporia subvermispora 132600.0 1 PMID:25965424 -1.2.1.95 * penicillium chrysogenum 171000.0 3 PMID:12509419 -1.2.1.95 * saccharomyces cerevisiae 155000.0 1 PMID:10320345 -1.2.1.98 * mycolicibacterium austroafricanum 55000.0 1 PMID:16622053 -1.2.1.99 * klebsiella pneumoniae 53800.0 2 PMID:22952017 -1.2.2.1 * pseudomonas aeruginosa 330000.0 1 PMID:3038081 -1.2.3.1 * amyelois transitella 280000.0 2 PMID:23826341 -1.2.3.1 * arabidopsis thaliana 147000.0 1 PMID:28188272 -1.2.3.1 * bombyx mori 260000.0 3 PMID:17904312;PMID:30286706 -1.2.3.1 * bos taurus 300000.0 3 PMID:10190983;PMID:12226218;PMID:4051501;PMID:8537361;PMID:9920943 -1.2.3.1 * burkholderia sp. aiu 129 130000.0 4 PMID:25283808 -1.2.3.1 * cavia porcellus 300000.0 3 PMID:10190983;PMID:11913970;PMID:12226218;PMID:3755579;PMID:4051501;PMID:8537361 -1.2.3.1 * culex quinquefasciatus 302000.0 2 PMID:11846778 -1.2.3.1 * desulfovibrio aminophilus 200000.0 2 PMID:10679276;PMID:16290059 -1.2.3.1 * desulfovibrio desulfuricans 200000.0 2 PMID:10679276;PMID:16290059 -1.2.3.1 * drosophila melanogaster 280000.0 2 PMID:816650 -1.2.3.1 * gallus gallus 150000.0 1 PMID:16672219 -1.2.3.1 * homo sapiens 150000.0 1 PMID:19741035 -1.2.3.1 * hordeum vulgare 160000.0 4 PMID:12654033 -1.2.3.1 * lupinus albus 145000.0 2 PMID:15915639 -1.2.3.1 * macaca fascicularis 300000.0 4 PMID:17603152 -1.2.3.1 * medicago truncatula 145000.0 2 PMID:15915639 -1.2.3.1 * mesocricetus auratus 288000.0 2 PMID:10598038 -1.2.3.1 * methylobacillus sp. 142000.0 4 PMID:16233281;PMID:29319807 -1.2.3.1 * methylobacillus sp. ky4400 142000.0 1 PMID:16233281;PMID:29319807 -1.2.3.1 * mus musculus 300000.0 8 PMID:10190983;PMID:10377246;PMID:12226218;PMID:15383531;PMID:21705476;PMID:4051501;PMID:8537361;PMID:9015384 -1.2.3.1 * oryctolagus cuniculus 280000.0 5 PMID:4698232;PMID:8262244 -1.2.3.1 * pseudomonas sp. 140000.0 10 PMID:14659539;PMID:16233281;PMID:18930009 -1.2.3.1 * rattus norvegicus 300000.0 6 PMID:11913970;PMID:12226218;PMID:17353002;PMID:17620217;PMID:3755579;PMID:8537361;PMID:9920943 -1.2.3.1 * streptomyces moderatus 148000.0 4 PMID:16233281 -1.2.3.1 * streptomyces rimosus 150000.0 4 PMID:16672219 -1.2.3.1 * stutzerimonas stutzeri 160000.0 4 PMID:15657722 -1.2.3.1 * sus scrofa 270000.0 1 PMID:4698232 -1.2.3.1 * zea mays 300000.0 2 PMID:10190983;PMID:12226218;PMID:4051501;PMID:8537361;PMID:9920943 -1.2.3.14 * lathyrus oleraceus 302000.0 2 PMID:23876699 -1.2.3.15 * phanerodontia chrysosporium 70000.0 3 PMID:11607073;PMID:23323052;PMID:8346264 -1.2.3.3 * lactiplantibacillus plantarum 262000.0 2 PMID:6480556 -1.2.3.3 * lactobacillus delbrueckii 694000.0 2 PMID:32448120 -1.2.3.3 * staphylococcus aureus 63700.0 1 PMID:15916614 -1.2.3.4 * abortiporus biennis 58000.0 1 PMID:27337220 -1.2.3.4 * amaranthus spinosus 130000.0 2 * -1.2.3.4 * gelatoporia subvermispora 400000.0 6 PMID:10356293;PMID:16000768;PMID:21376010 -1.2.3.4 * hordeum vulgare 140000.0 6 PMID:11862550;PMID:18943123;PMID:9143327;PMID:9576772;PMID:9765992 -1.2.3.4 * oryza sativa 295700.0 12 PMID:26347131 -1.2.3.4 * pseudomonas sp. 320000.0 2 * -1.2.3.4 * rhododendron mucronatum 120000.0 1 PMID:25677624 -1.2.3.4 * sorghum bicolor 124000.0 2 PMID:21469601 -1.2.3.4 * sorghum sp. 120200.0 2 PMID:8422416 -1.2.3.4 * triticum aestivum 26000.0 1 PMID:17399681 -1.2.3.5 * tyromyces palustris 127000.0 1 * -1.2.4.1 * bos taurus 154000.0 3 PMID:7144580 -1.2.4.1 * escherichia coli 200000.0 7 PMID:11955070;PMID:15518552;PMID:18216265;PMID:23088422;PMID:23580650;PMID:7011811 -1.2.4.1 * geobacillus stearothermophilus 152000.0 3 PMID:17157320;PMID:2200674 -1.2.4.1 * homo sapiens 160000.0 1 PMID:7756842 -1.2.4.1 * pseudomonas putida 185000.0 3 * -1.2.4.1 * rattus norvegicus 43000.0 2 PMID:15522199;PMID:20644337 -1.2.4.1 * sus scrofa 150000.0 2 PMID:3840997;PMID:956154 -1.2.4.1 * zymomonas mobilis 240000.0 2 PMID:15876566 -1.2.4.2 * azotobacter vinelandii 105687.0 2 PMID:2404759 -1.2.4.2 * bacillus subtilis 110000.0 1 PMID:2500417 -1.2.4.2 * corynebacterium glutamicum 140000.0 1 PMID:16522631 -1.2.4.2 * escherichia coli 210000.0 2 PMID:17367808;PMID:6373436 -1.2.4.2 * picosynechococcus sp. pcc 7002 247000.0 1 PMID:29574001 -1.2.4.2 * rattus norvegicus 117400.0 1 PMID:18783430 -1.2.4.2 * salmonella enterica subsp. enterica serovar typhimurium 110000.0 2 * -1.2.4.4 * bos taurus 154000.0 7 PMID:2853817;PMID:3004826 -1.2.4.4 * homo sapiens 45500.0 2 PMID:9582350 -1.2.4.4 * oryctolagus cuniculus 47000.0 2 * -1.2.4.4 * pseudomonas putida 190000.0 6 PMID:10989425;PMID:10989441;PMID:8521848 -1.2.4.4 * rattus norvegicus 190000.0 5 PMID:3619032;PMID:8521848 -1.2.4.4 * saccharomyces cerevisiae 478000.0 2 PMID:10989447;PMID:8136709 -1.2.4.4 * thermoplasma acidophilum 46460.0 2 PMID:17894823 -1.2.5.1 * escherichia coli 265000.0 5 PMID:13785427;PMID:2040613;PMID:3016647;PMID:3545288 -1.2.5.2 * acetobacter aceti 137000.0 4 * -1.2.5.2 * acetobacter sp. 78000.0 6 PMID:16636451 -1.2.5.2 * comamonas testosteroni 70000.0 1 PMID:3521592 -1.2.5.2 * cupriavidus necator 79500.0 3 PMID:11222593;PMID:9406410 -1.2.5.2 * gluconacetobacter diazotrophicus 129000.0 8 PMID:18321602;PMID:20802042 -1.2.5.2 * gluconobacter oxydans 140000.0 1 * -1.2.5.2 * gluconobacter sp. 141000.0 3 * -1.2.5.2 * pseudomonas aeruginosa 120000.0 5 PMID:2673029;PMID:3144289;PMID:6439190 -1.2.5.2 * pseudomonas putida 130000.0 7 PMID:2673029;PMID:7730276 -1.2.5.2 * rhizorhabdus wittichii 450000.0 8 PMID:23828599 -1.2.5.2 * thauera butanivorans 69000.0 3 PMID:11238982;PMID:11889098 -1.2.5.3 * aeropyrum pernix 168100.0 4 * -1.2.5.3 * afipia carboxidovorans 285000.0 7 PMID:10636886;PMID:21774528;PMID:29676148 -1.2.5.3 * bradyrhizobium japonicum 230000.0 4 PMID:10788353 -1.2.5.3 * hydrogenophaga pseudoflava 87224.0 3 PMID:10482497 -1.2.7.1 * aeropyrum pernix 110000.0 5 PMID:15848165 -1.2.7.1 * archaeoglobus fulgidus 125000.0 6 PMID:7710318 -1.2.7.1 * chlamydomonas reinhardtii 235000.0 3 PMID:23154536;PMID:23258532 -1.2.7.1 * citrobacter sp. 240000.0 2 PMID:28040649 -1.2.7.1 * giardia duodenalis 545000.0 3 PMID:21349979;PMID:8855555 -1.2.7.1 * hydrogenobacter thermophilus 265000.0 11 PMID:16343420;PMID:9094223 -1.2.7.1 * methanococcus maripaludis 190000.0 1 PMID:12743680 -1.2.7.1 * methanosarcina barkeri 130000.0 5 PMID:8620891 -1.2.7.1 * pseudothermotoga hypogea 157000.0 5 PMID:26032540 -1.2.7.1 * pyrococcus furiosus 100000.0 4 PMID:8380721 -1.2.7.1 * thermoanaerobacter kivui 245000.0 1 PMID:33660937 -1.2.7.1 * thermococcus guaymasensis 258000.0 5 PMID:24982594 -1.2.7.1 * thermococcus kodakarensis 240000.0 1 PMID:28040649 -1.2.7.1 * thermotoga maritima 156000.0 10 PMID:26032540;PMID:8305426 -1.2.7.1 * trichomonas vaginalis 120000.0 2 PMID:22130740;PMID:26951982 -1.2.7.10 * neomoorella thermoacetica 243000.0 9 PMID:20956531 -1.2.7.11 * aeropyrum pernix 100000.0 5 PMID:15848165 -1.2.7.11 * halobacterium salinarum 165000.0 3 PMID:6266826 -1.2.7.11 * saccharolobus solfataricus 103000.0 5 PMID:16466637 -1.2.7.11 * sulfolobus sp. 105000.0 5 PMID:11398472;PMID:11683888 -1.2.7.11 * sulfurisphaera tokodaii 70000.0 4 PMID:27619895 -1.2.7.12 * desulfitobacterium hafniense 17400.0 1 PMID:20944230 -1.2.7.12 * methanosarcina barkeri 440000.0 13 PMID:2125267;PMID:8617280 -1.2.7.12 * methanothermobacter thermautotrophicus 160000.0 6 PMID:1915887;PMID:8161283 -1.2.7.12 * methanothermobacter wolfeii 260000.0 8 PMID:1330558 -1.2.7.12 * syntrophus aciditrophicus 21500.0 1 PMID:20944230 -1.2.7.12 * thermoplasma acidophilum 23100.0 1 PMID:20944230 -1.2.7.3 * helicobacter pylori 43000.0 4 PMID:23002221 -1.2.7.3 * hydrogenobacter thermophilus 230000.0 8 PMID:11401501;PMID:14652015;PMID:8655524 -1.2.7.3 * prosthecochloris vibrioformis f. thiosulfatophilum 220000.0 1 PMID:4628267 -1.2.7.3 * thauera aromatica 200000.0 3 PMID:12081970 -1.2.7.3 * thermococcus litoralis 210000.0 5 PMID:8830683 -1.2.7.4 * aeropyrum pernix 210000.0 5 * -1.2.7.4 * afipia carboxidovorans 273500.0 4 PMID:10430865;PMID:7721710 -1.2.7.4 * bradyrhizobium japonicum 235000.0 5 PMID:10788353 -1.2.7.4 * carboxydothermus hydrogenoformans 450000.0 5 PMID:12423371;PMID:21737917 -1.2.7.4 * citrobacter amalonaticus 140000.0 2 * -1.2.7.4 * clostridium carboxidivorans 300000.0 1 PMID:28625981 -1.2.7.4 * hydrogenophaga pseudoflava 87224.0 3 PMID:10482497 -1.2.7.4 * methanococcus vannielii 220000.0 3 PMID:3624199 -1.2.7.4 * methanosarcina barkeri 3000000.0 17 PMID:1939246;PMID:3818661;PMID:6425262 -1.2.7.4 * methanosarcina mazei 94000.0 2 PMID:8662887 -1.2.7.4 * methanosarcina thermophila 1000000.0 8 PMID:18203715;PMID:3023296 -1.2.7.4 * methanothrix soehngenii 190000.0 3 PMID:2714294 -1.2.7.4 * mycobacterium sp. 85970.0 3 PMID:20035005 -1.2.7.4 * neomoorella thermoacetica 436000.0 16 PMID:17887777;PMID:2569891;PMID:6687389;PMID:6893049;PMID:8639680 -1.2.7.4 * rhodospirillum rubrum 61800.0 2 PMID:3029096 -1.2.7.5 * aromatoleum aromaticum 280000.0 2 PMID:24214948;PMID:30766522 -1.2.7.5 * caldicellulosiruptor bescii 315000.0 2 PMID:31097544 -1.2.7.5 * desulfovibrio aminophilus 200000.0 2 PMID:16290059 -1.2.7.5 * pyrobaculum aerophilum 130000.0 2 PMID:15772818 -1.2.7.5 * pyrococcus furiosus 280000.0 13 PMID:11265456;PMID:1907273;PMID:20562313;PMID:7642512;PMID:7878465;PMID:9973343 -1.2.7.5 * thermococcus litoralis 280000.0 1 PMID:11265456 -1.2.7.5 * thermococcus sp. 105000.0 2 PMID:11265456;PMID:7642503 -1.2.7.6 * caldicellulosiruptor bescii 315000.0 2 PMID:11265456;PMID:31097544 -1.2.7.6 * methanococcus maripaludis 70000.0 1 PMID:17704226 -1.2.7.6 * pyrobaculum aerophilum 70000.0 5 PMID:17559573;PMID:7721730 -1.2.7.6 * pyrococcus furiosus 74089.0 7 PMID:11265456;PMID:17559573;PMID:20562313;PMID:31097544;PMID:7721730;PMID:9774434 -1.2.7.7 * methanothermobacter thermautotrophicus 55000.0 3 PMID:9108258 -1.2.7.7 * pyrococcus furiosus 43960.0 4 PMID:8550425 -1.2.7.7 * pyrococcus sp. 47000.0 4 PMID:11265457;PMID:8550513 -1.2.7.7 * thermococcus litoralis 230000.0 5 PMID:11265457;PMID:8550513 -1.2.7.7 * thermococcus profundus 220000.0 6 PMID:15713889 -1.2.7.8 * methanothermobacter thermautotrophicus 67000.0 2 PMID:9108258 -1.2.7.8 * pyrococcus furiosus 180000.0 5 PMID:11265457;PMID:8206994;PMID:9742957 -1.2.7.8 * thermococcus kodakarensis 192000.0 1 PMID:9742957 -1.2.7.8 * thermococcus profundus 170000.0 6 PMID:22608551 -1.2.98.1 * methylobacterium sp. fd1 188000.0 3 PMID:32281473 -1.2.98.1 * pseudomonas putida 220000.0 5 PMID:11866124;PMID:27836796;PMID:3514215;PMID:7766017 -1.2.99.6 * clostridium formicaceticum 125000.0 2 PMID:1793519;PMID:7642503 -1.2.99.6 * megalodesulfovibrio gigas 126000.0 2 PMID:7592385 -1.2.99.6 * neomoorella thermoacetica 300000.0 8 PMID:1586452;PMID:2550230 -1.2.99.6 * peptoclostridium acidaminophilum 67000.0 2 PMID:14686934 -1.2.99.6 * thermococcus sp. 105000.0 2 PMID:1793519;PMID:7642503 -1.2.99.7 * megalodesulfovibrio gigas 200000.0 5 PMID:7592385;PMID:8354279 -1.2.99.7 * oleidesulfovibrio alaskensis 206000.0 2 PMID:10727945 -1.2.99.8 * sulfolobus acidocaldarius 177000.0 4 PMID:10095793 -1.2.99.8 * sulfurisphaera tokodaii 372000.0 12 PMID:26808202 -1.20.1.1 * pseudomonas sp. 70000.0 2 PMID:22238013 -1.20.1.1 * stutzerimonas stutzeri 69000.0 4 PMID:11278981;PMID:14529270;PMID:15779903 -1.20.2.1 * arsenite-oxidising bacterium 219000.0 3 PMID:14996791 -1.20.2.1 * hydrogenophaga sp. 306000.0 3 PMID:15178476 -1.20.2.1 * pseudorhizobium banfieldiae 219000.0 3 PMID:14996791 -1.20.4.1 * arabidopsis thaliana 14500.0 1 PMID:16567632 -1.20.4.1 * nostoc sp. 13624.0 1 PMID:23086594 -1.20.4.1 * saccharomyces cerevisiae 34000.0 2 PMID:10801893 -1.20.4.1 * synechocystis sp. 15000.0 3 PMID:20960080;PMID:22155275 -1.20.4.2 * homo sapiens 28000.0 1 PMID:11511179 -1.20.4.3 * salinispora tropica 43000.0 1 PMID:20947511 -1.20.4.4 * corynebacterium glutamicum 60000.0 2 PMID:22032722 -1.20.4.4 * oleidesulfovibrio alaskensis 20000.0 4 PMID:25139711 -1.20.4.4 * salinispora tropica 47000.0 1 PMID:20947511 -1.20.4.4 * staphylococcus aureus 21000.0 9 PMID:10606519;PMID:10681053;PMID:15147840;PMID:15159594;PMID:8003493 -1.20.4.4 * thermus thermophilus 17000.0 2 PMID:23800470 -1.20.9.1 * alcaligenes faecalis 85000.0 1 PMID:1331097 -1.20.9.1 * arthrobacter sp. 100000.0 2 PMID:19214757 -1.20.9.1 * chrysiogenes arsenatis 123000.0 3 PMID:9738904 -1.20.99.1 * chrysiogenes arsenatis 123000.0 3 PMID:9738904 -1.20.99.1 * homo sapiens 71800.0 1 * -1.20.99.1 * hydrogenophaga sp. nt-26 219000.0 3 PMID:15178476 -1.20.99.1 * hydrogenophaga sp. nt14 306000.0 3 PMID:15178476 -1.20.99.1 * leishmania major 14500.0 1 PMID:17012788 -1.20.99.1 * oryza sativa 14960.0 2 PMID:17388894 -1.21.1.1 * bos taurus 42000.0 2 PMID:500717 -1.21.1.1 * homo sapiens 33000.0 2 PMID:15289438;PMID:25395621 -1.21.1.1 * mus musculus 32800.0 2 PMID:16316988;PMID:22238141 -1.21.1.1 * sus scrofa 33000.0 2 PMID:15289438;PMID:16316988;PMID:22238141 -1.21.3.1 * amycolatopsis lactamdurans 26500.0 1 PMID:3183613 -1.21.3.1 * flavobacterium sp. 38000.0 1 PMID:2793834 -1.21.3.1 * pseudomonas aeruginosa 37000.0 1 PMID:31097228 -1.21.3.1 * streptomyces microflavus 37800.0 1 PMID:10721485 -1.21.3.3 * berberis beaniana 54000.0 2 * -1.21.3.3 * eschscholzia californica 59599.0 1 PMID:16728404 -1.21.3.4 * penicillium glabrum 230000.0 5 PMID:7049104;PMID:8820909 -1.21.3.5 * oospora sulphurea-ochracea 128000.0 1 PMID:7049104 -1.21.3.6 * antirrhinum majus 40000.0 3 PMID:11073455;PMID:16367960 -1.21.3.7 * cannabis sativa 79000.0 11 PMID:15190053;PMID:16511162;PMID:17669365;PMID:22495534 -1.21.3.8 * cannabis sativa 75000.0 4 PMID:17544411;PMID:8663284 -1.21.4.1 * acetoanaerobium sticklandii 870000.0 9 PMID:10085076;PMID:11422384;PMID:1262330;PMID:8203910 -1.21.4.2 * acetoanaerobium sticklandii 240000.0 7 PMID:11422384;PMID:15450486;PMID:3255358;PMID:7892245 -1.21.4.2 * peptoclostridium acidaminophilum 420000.0 7 PMID:10091582;PMID:1587286;PMID:1917832 -1.21.4.2 * peptoclostridium litorale 47000.0 3 PMID:1917832;PMID:8529640 -1.21.4.2 * tissierella creatinophila 240000.0 3 PMID:15450486 -1.21.4.2 * treponema denticola 240000.0 5 PMID:11797052;PMID:15450486 -1.21.4.3 * tissierella creatinophila 45000.0 2 PMID:9799288 -1.21.4.4 * peptoclostridium acidaminophilum 200000.0 3 PMID:8529639 -1.21.4.5 * sphingobium chlorophenolicum 60000.0 1 PMID:1459949 -1.21.4.5 * sphingobium sp. ug30 56000.0 4 PMID:12459186;PMID:19682569 -1.21.98.2 * lentzea aerocolonigenes 113000.0 4 PMID:16313168 -1.21.98.3 * rubrivivax gelatinosus 86000.0 3 PMID:14617630 -1.21.99.1 * penicillium cyclopium 50000.0 1 PMID:5143339 -1.21.99.3 * chiloscyllium punctatum 29400.0 1 PMID:18397787 -1.21.99.3 * gallus gallus 30000.0 1 PMID:12072404 -1.21.99.3 * homo sapiens 65000.0 2 PMID:12586771;PMID:12746313 -1.21.99.3 * rattus norvegicus 31000.0 1 PMID:1547744 -1.21.99.4 * homo sapiens 62000.0 2 PMID:12586771 -1.21.99.4 * rattus norvegicus 29000.0 3 PMID:11044448;PMID:11898402;PMID:1547744 -1.21.99.4 * rattus sp. 200000.0 7 PMID:10829019;PMID:1503562;PMID:1993696;PMID:7248319 -1.21.99.5 * dehalobacter restrictus 71000.0 4 PMID:12902251;PMID:9224702 -1.21.99.5 * dehalococcoides mccartyi 51000.0 1 PMID:10671186 -1.21.99.5 * dehalococcoides sp. 50000.0 1 PMID:20357835 -1.21.99.5 * desulfitobacterium hafniense 200000.0 4 PMID:11511863;PMID:12902251;PMID:9575235 -1.21.99.5 * desulfitobacterium sp. 58000.0 1 PMID:15959725 -1.21.99.5 * desulfitobacterium sp. pce1 48000.0 1 PMID:11511863 -1.21.99.5 * paraclostridium bifermentans 70000.0 3 PMID:11400736 -1.21.99.5 * sulfurospirillum multivorans 61000.0 8 PMID:12420164;PMID:24433392;PMID:8663199;PMID:9696761 -1.21.99.5 * uncultured bacterium 56000.0 2 PMID:20530887 -1.23.1.1 * forsythia x intermedia 59000.0 2 PMID:8910615 -1.23.1.1 * linum corymbulosum 36400.0 1 PMID:18489708 -1.23.1.1 * sphingobium sp. 36837.0 3 PMID:23199737 -1.23.1.2 * forsythia x intermedia 59000.0 2 PMID:8910615 -1.23.1.2 * linum corymbulosum 36400.0 1 PMID:18489708 -1.23.5.1 * lactuca sativa 60000.0 2 PMID:102251;PMID:8742341 -1.23.5.1 * phyllostachys edulis 39600.0 1 PMID:23640082 -1.23.5.1 * spinacia oleracea 45800.0 3 PMID:24271609 -1.3.1.1 * escherichia coli 45069.0 4 PMID:21169495 -1.3.1.1 * homo sapiens 220000.0 2 PMID:17324113 -1.3.1.1 * shigella flexneri 40400.0 1 PMID:18045236 -1.3.1.10 * escherichia coli 33000.0 1 PMID:9022698 -1.3.1.10 * porphyromonas gingivalis 66000.0 2 PMID:22820244;PMID:29400320 -1.3.1.10 * salmonella enterica subsp. enterica serovar typhimurium 27770.0 1 PMID:2687243 -1.3.1.10 * staphylococcus aureus 30000.0 1 PMID:18335995 -1.3.1.10 * streptococcus pneumoniae 34000.0 1 PMID:10910344 -1.3.1.10 * streptomyces collinus 75000.0 3 PMID:8955309 -1.3.1.100 * aspergillus fumigatus 46000.0 2 PMID:20526482 -1.3.1.101 * thermoplasma acidophilum 45000.0 2 PMID:16788058;PMID:17275067 -1.3.1.102 * nicotiana tabacum 74000.0 7 PMID:11117876;PMID:17945329 -1.3.1.103 * burkholderia sp. 37000.0 4 PMID:15781461 -1.3.1.104 * bacillus subtilis 27100.0 1 PMID:21185310 -1.3.1.105 * fragaria x ananassa 83800.0 3 PMID:16517758;PMID:28283921 -1.3.1.107 * eschscholzia californica 29432.0 2 PMID:17080644 -1.3.1.108 * acetobacterium woodii 350000.0 4 PMID:23479729 -1.3.1.109 * acidaminococcus fermentans 42000.0 1 PMID:24379410 -1.3.1.109 * clostridium kluyveri 320000.0 7 PMID:17993531;PMID:22800682 -1.3.1.109 * clostridium tetanomorphum 574000.0 4 PMID:22800682 -1.3.1.111 * synechocystis sp. 44869.0 1 PMID:8766814 -1.3.1.112 * vitis vinifera 43000.0 1 * -1.3.1.116 * [clostridium] scindens 210000.0 4 PMID:18047844;PMID:7599167;PMID:8491719 -1.3.1.118 * mycobacterium tuberculosis 114600.0 2 PMID:17600151;PMID:7599116 -1.3.1.119 * xanthobacter flavus 110000.0 1 PMID:8599538 -1.3.1.12 * aquifex aeolicus 37000.0 2 PMID:16731976 -1.3.1.12 * archaeoglobus fulgidus 420000.0 3 PMID:19082689 -1.3.1.12 * candida maltosa 75000.0 1 * -1.3.1.12 * cupriavidus necator 65000.0 1 PMID:1262315 -1.3.1.12 * escherichia coli 100000.0 4 PMID:3298984;PMID:4929151;PMID:6338013;PMID:6395895;PMID:6396419;PMID:7044424;PMID:7049251 -1.3.1.12 * haemophilus influenzae 43022.0 1 PMID:28025081 -1.3.1.12 * klebsiella aerogenes 81000.0 1 PMID:5456988 -1.3.1.12 * microtetraspora glauca 68000.0 1 PMID:2775485 -1.3.1.12 * mycobacterium tuberculosis 36420.0 2 PMID:16889979 -1.3.1.12 * pseudomonas aeruginosa 150000.0 2 PMID:407230;PMID:804859 -1.3.1.12 * saccharomyces cerevisiae 52500.0 1 PMID:2697638 -1.3.1.12 * streptococcus mutans 66000.0 3 * -1.3.1.12 * uncultured bacterium 31400.0 1 PMID:23479063 -1.3.1.120 * streptomyces collinus 75000.0 1 PMID:1597409 -1.3.1.124 * homo sapiens 36066.0 1 PMID:7818482 -1.3.1.124 * mus musculus 31300.0 1 PMID:10464321 -1.3.1.124 * rattus norvegicus 120000.0 3 PMID:10497069;PMID:6526815;PMID:8344281 -1.3.1.124 * saccharomyces cerevisiae 69000.0 1 PMID:9268358 -1.3.1.124 * yarrowia lipolytica 360000.0 1 PMID:4019437 -1.3.1.13 * acinetobacter calcoaceticus 210000.0 1 PMID:4074072 -1.3.1.13 * ignicoccus hospitalis 85000.0 2 PMID:27290727;PMID:28025081 -1.3.1.13 * nanoarchaeum equitans 71000.0 1 PMID:27290727 -1.3.1.13 * vigna radiata 52000.0 1 PMID:16661043 -1.3.1.14 * bacillus subtilis 114000.0 9 PMID:10545205 -1.3.1.14 * bifidobacterium bifidum 130000.0 1 PMID:19060157 -1.3.1.14 * enterococcus faecalis 125000.0 3 PMID:10529184 -1.3.1.14 * faecalicatena orotica 124000.0 5 PMID:10956027;PMID:13825167;PMID:5702049 -1.3.1.14 * lactococcus lactis 34120.0 1 PMID:8021180 -1.3.1.19 * pseudomonas fluorescens 160000.0 2 PMID:20632934 -1.3.1.19 * pseudomonas putida 220000.0 5 PMID:10356973;PMID:859182;PMID:8824602 -1.3.1.19 * pseudomonas sp. 440000.0 2 PMID:4362337 -1.3.1.2 * bos taurus 216000.0 2 PMID:8373446 -1.3.1.2 * cupriavidus necator 210000.0 2 PMID:8806723 -1.3.1.2 * homo sapiens 210000.0 3 PMID:25317816;PMID:8373446 -1.3.1.2 * ovis aries 111000.0 1 PMID:26758717 -1.3.1.2 * rattus norvegicus 220000.0 5 PMID:6433973;PMID:7451435;PMID:8373446 -1.3.1.2 * sus scrofa 220000.0 7 PMID:15450176;PMID:2806259;PMID:8373446;PMID:9226714;PMID:9860876 -1.3.1.20 * canis sp. 65000.0 2 PMID:2697716;PMID:7852295 -1.3.1.20 * cavia porcellus 36000.0 3 PMID:3548826 -1.3.1.20 * homo sapiens 36000.0 4 PMID:17266043;PMID:8543560 -1.3.1.20 * macaca fascicularis 70000.0 2 PMID:15618685;PMID:17654552 -1.3.1.20 * macaca fuscata 78000.0 5 PMID:11097839;PMID:2697716;PMID:3300644;PMID:7852295 -1.3.1.20 * macaca fuscata fuscata 36000.0 1 PMID:15618685 -1.3.1.20 * mus musculus 65000.0 7 PMID:2691507;PMID:6401153 -1.3.1.20 * rattus norvegicus 37029.0 3 PMID:7430089;PMID:8146147;PMID:9261071 -1.3.1.20 * sus scrofa 39000.0 2 PMID:2690827 -1.3.1.21 * homo sapiens 55000.0 3 PMID:11111101;PMID:12914579;PMID:27697512 -1.3.1.21 * mortierella alpina 53970.0 1 PMID:17220261 -1.3.1.21 * rattus norvegicus 54200.0 1 PMID:11111101 -1.3.1.22 * homo sapiens 42000.0 3 PMID:15538746;PMID:18258185 -1.3.1.22 * pseudomonadota bacterium 27500.0 1 PMID:33469028 -1.3.1.22 * rattus norvegicus 35000.0 4 PMID:17826869;PMID:4810062;PMID:7893662 -1.3.1.24 * arabidopsis sp. 38000.0 1 PMID:11226195 -1.3.1.24 * bos taurus 36000.0 4 PMID:26395865;PMID:7262442 -1.3.1.24 * cavia porcellus 70000.0 1 PMID:4401301 -1.3.1.24 * homo sapiens 69000.0 9 PMID:11773068;PMID:18276984;PMID:19217170;PMID:25196843;PMID:26393580;PMID:27316791;PMID:8424666 -1.3.1.24 * mus musculus 46000.0 4 PMID:25196843;PMID:26393580;PMID:3060109 -1.3.1.24 * rattus norvegicus 68000.0 17 PMID:16287987;PMID:18276984;PMID:2705777;PMID:2722768;PMID:2917554;PMID:3060109;PMID:3689807;PMID:40968;PMID:7092884;PMID:7217067;PMID:8020496;PMID:8566332 -1.3.1.24 * salmo salar 68000.0 1 PMID:12943508 -1.3.1.24 * sus scrofa 34000.0 1 PMID:40968 -1.3.1.25 * acinetobacter calcoaceticus 62000.0 2 PMID:2824437 -1.3.1.25 * cupriavidus necator 94600.0 2 PMID:4341530 -1.3.1.25 * pseudomonas putida 110000.0 3 PMID:2183008 -1.3.1.27 * hordeum vulgare 38000.0 1 PMID:16248576 -1.3.1.27 * mucor circinelloides 26000.0 1 * -1.3.1.27 * rattus norvegicus 135000.0 3 PMID:1150153 -1.3.1.28 * escherichia coli 210000.0 2 PMID:2521622;PMID:3040680 -1.3.1.29 * mucor circinelloides 541000.0 1 PMID:28975438 -1.3.1.29 * nocardia sp. 92000.0 1 PMID:62750 -1.3.1.29 * novosphingobium aromaticivorans 110000.0 3 PMID:16820465 -1.3.1.29 * pseudomonas putida 160000.0 6 PMID:28089880;PMID:4369091;PMID:62750 -1.3.1.3 * digitalis canariensis 45000.0 1 PMID:16858667 -1.3.1.3 * digitalis lanata 40000.0 1 PMID:16386278 -1.3.1.3 * digitalis purpurea 43963.0 2 PMID:17184799 -1.3.1.3 * homo sapiens 65000.0 1 PMID:18624455 -1.3.1.3 * rattus norvegicus 37000.0 1 PMID:6736016 -1.3.1.3 * sus scrofa 30000.0 1 PMID:4149531 -1.3.1.31 * achromobacter sp. 45000.0 2 PMID:23644746 -1.3.1.31 * artemisia annua 38500.0 1 PMID:29743047 -1.3.1.31 * clostridium sp. 450000.0 2 PMID:477658 -1.3.1.31 * clostridium tyrobutyricum 940000.0 4 PMID:4005048 -1.3.1.31 * eubacterium ramulus 75000.0 2 PMID:24459060 -1.3.1.31 * gluconobacter oxydans 44000.0 2 PMID:20717668 -1.3.1.31 * lacticaseibacillus casei 170000.0 3 PMID:22579387 -1.3.1.31 * neomoorella thermoacetica 600000.0 2 PMID:11060310 -1.3.1.31 * photorhabdus luminescens 42500.0 2 * -1.3.1.32 * cupriavidus necator 72000.0 3 PMID:8226615 -1.3.1.32 * cutaneotrichosporon cutaneum 81000.0 3 PMID:7387635;PMID:8226615 -1.3.1.32 * pimelobacter simplex 37000.0 1 PMID:10395975 -1.3.1.32 * pseudomonas aeruginosa 74000.0 2 PMID:7814320;PMID:8407778;PMID:8550433 -1.3.1.32 * pseudomonas sp. 74000.0 3 PMID:7814320;PMID:8226615;PMID:8407778;PMID:8550433 -1.3.1.32 * ralstonia sp. 40000.0 3 PMID:20054138;PMID:20359211 -1.3.1.32 * rhizobium sp. 36410.0 2 PMID:17158677;PMID:27040018 -1.3.1.32 * rhodococcus jostii 34000.0 1 PMID:26319878 -1.3.1.32 * rhodococcus opacus 38000.0 1 PMID:9657989 -1.3.1.32 * sphingobium chlorophenolicum 36000.0 1 PMID:19242755 -1.3.1.32 * sphingomonas sp. 37100.0 1 PMID:21755281 -1.3.1.33 * arabidopsis thaliana 40150.0 2 PMID:11866453;PMID:28260138 -1.3.1.33 * avena sativa 41000.0 8 PMID:10518779;PMID:1689568;PMID:6456902;PMID:7306062;PMID:7306063;PMID:7470097 -1.3.1.33 * chlamydomonas reinhardtii 36000.0 2 * -1.3.1.33 * cucurbita pepo 37000.0 2 PMID:11785941;PMID:24232546;PMID:24232547;PMID:24249610;PMID:6696447 -1.3.1.33 * hordeum vulgare 63000.0 13 PMID:10518779;PMID:16502318;PMID:18723681;PMID:2671659;PMID:7306062;PMID:7439188;PMID:7659751 -1.3.1.33 * lathyrus oleraceus 78800.0 1 * -1.3.1.33 * phaeodactylum tricornutum 61000.0 4 PMID:1689568;PMID:27367227 -1.3.1.33 * phaseolus vulgaris 100000.0 4 PMID:7306062;PMID:7306063 -1.3.1.33 * prochlorococcus marinus 360000.0 1 PMID:23341615 -1.3.1.33 * prochlorococcus marinus subsp. marinus str. ccmp1375 210000.0 5 PMID:18693243 -1.3.1.33 * rhodobacter capsulatus 60000.0 6 PMID:15953479 -1.3.1.33 * triticum aestivum 112000.0 4 PMID:11785941;PMID:18071923;PMID:24232546;PMID:24232547;PMID:24249610;PMID:6696447 -1.3.1.34 * escherichia coli 72550.0 1 PMID:9346310 -1.3.1.34 * homo sapiens 34000.0 2 PMID:11514237;PMID:14550650 -1.3.1.34 * saccharomyces cerevisiae 69000.0 2 PMID:9268358 -1.3.1.38 * escherichia coli 80000.0 2 PMID:6378898 -1.3.1.38 * homo sapiens 75000.0 2 PMID:10811639;PMID:16546181 -1.3.1.38 * mus musculus 32600.0 1 PMID:10811639 -1.3.1.39 * porphyromonas gingivalis 33090.0 1 PMID:22820244 -1.3.1.40 * pseudomonas sp. 'cruciviae' 170000.0 1 * -1.3.1.41 * drosophila melanogaster 55000.0 1 * -1.3.1.42 * arabidopsis thaliana 41170.0 1 PMID:9346960 -1.3.1.42 * capnoides sempervirens 42500.0 2 PMID:9847108 -1.3.1.42 * hordeum vulgare 40300.0 1 * -1.3.1.42 * oryza sativa 41000.0 1 PMID:12569412 -1.3.1.42 * pseudomonas putida 82200.0 2 PMID:9585575 -1.3.1.42 * zea mays 54000.0 1 PMID:16664582 -1.3.1.43 * actinoplanes missouriensis 68000.0 2 PMID:2590341 -1.3.1.43 * phenylobacterium immobile 69000.0 4 PMID:3967752 -1.3.1.43 * pseudomonas aeruginosa 150000.0 2 PMID:2123197 -1.3.1.43 * streptomyces phaeochromogenes 66300.0 2 PMID:4074498 -1.3.1.43 * stutzerimonas stutzeri 66000.0 2 PMID:11790331 -1.3.1.43 * zymomonas mobilis 32000.0 1 PMID:7916685 -1.3.1.44 * clostridium acetobutylicum 45700.0 1 PMID:23050861 -1.3.1.44 * euglena gracilis 44000.0 4 PMID:15569691;PMID:3102464 -1.3.1.44 * mycolicibacterium smegmatis 72000.0 2 PMID:7251572;PMID:7451405 -1.3.1.44 * pseudomonas aeruginosa 28000.0 1 PMID:21301088 -1.3.1.44 * treponema denticola 44800.0 3 PMID:17382934;PMID:23050861 -1.3.1.45 * coffea arabica 34000.0 1 PMID:19756631 -1.3.1.45 * ginkgo biloba 33280.0 1 PMID:23459862 -1.3.1.46 * fusarium solani-melongenae 88000.0 1 * -1.3.1.48 * bos taurus 57000.0 3 PMID:224937;PMID:6290839;PMID:8382144 -1.3.1.48 * homo sapiens 68500.0 2 PMID:204253;PMID:6290839 -1.3.1.48 * rattus norvegicus 42000.0 2 PMID:7693121 -1.3.1.49 * alcaligenes faecalis 100000.0 2 * -1.3.1.5 * cucurbita maxima 32000.0 2 PMID:3707515 -1.3.1.51 * glycine max 34700.0 1 PMID:2306102 -1.3.1.53 * comamonas testosteroni 60000.0 2 * -1.3.1.54 * pseudomonas denitrificans (nom. rej.) 31000.0 5 PMID:1732193;PMID:7606163 -1.3.1.56 * comamonas testosteroni 123000.0 3 PMID:10819967;PMID:21045310;PMID:8702262 -1.3.1.57 * clostridium sp. 125000.0 1 PMID:27874239 -1.3.1.57 * coprococcus sp. 130000.0 1 PMID:16345897 -1.3.1.57 * eubacterium oxidoreducens 78000.0 3 PMID:27874239;PMID:2925649 -1.3.1.6 * leishmania donovani 65000.0 1 PMID:11846720 -1.3.1.6 * shewanella frigidimarina 63033.0 1 PMID:14609326 -1.3.1.6 * trypanosoma brucei 120000.0 1 * -1.3.1.67 * pseudomonas putida 96000.0 1 PMID:3711022 -1.3.1.69 * phaseolus vulgaris 55000.0 2 PMID:16666974 -1.3.1.70 * bos taurus 46750.0 2 PMID:11784322 -1.3.1.70 * rattus norvegicus 70000.0 2 PMID:7492613 -1.3.1.70 * saccharomyces cerevisiae 50610.0 1 PMID:1418625 -1.3.1.71 * saccharomyces cerevisiae 56000.0 1 PMID:10722850 -1.3.1.72 * homo sapiens 60100.0 2 PMID:11519011;PMID:17984220 -1.3.1.73 * rauvolfia serpentina 49000.0 2 PMID:12391554 -1.3.1.74 * arabidopsis thaliana 42000.0 1 PMID:21169366 -1.3.1.74 * artemisia annua 38500.0 1 * -1.3.1.74 * cucumis sativus 42000.0 2 PMID:21169366 -1.3.1.74 * rattus norvegicus 135000.0 5 PMID:1150153;PMID:18274955 -1.3.1.75 * rhodobacter capsulatus 200000.0 2 * -1.3.1.76 * escherichia coli 60000.0 3 * -1.3.1.76 * priestia megaterium 45000.0 2 PMID:12408752 -1.3.1.76 * salmonella enterica 50000.0 1 PMID:14595395 -1.3.1.77 * camellia sinensis 37000.0 1 PMID:23288883 -1.3.1.77 * glycine max 39000.0 1 PMID:22107112 -1.3.1.78 * [brevibacterium] flavum 158000.0 1 PMID:457594 -1.3.1.78 * acinetobacter calcoaceticus 210000.0 1 PMID:4074072 -1.3.1.78 * arabidopsis thaliana 600000.0 3 PMID:12354106 -1.3.1.78 * corynebacterium ammoniagenes 68000.0 1 PMID:457594 -1.3.1.78 * corynebacterium glutamicum 158000.0 1 PMID:457594 -1.3.1.78 * synechocystis sp. 70000.0 2 PMID:16615917 -1.3.1.78 * vigna radiata 52000.0 1 PMID:16661043 -1.3.1.8 * bos taurus 98000.0 4 PMID:3994691 -1.3.1.8 * candida albicans 180000.0 2 PMID:4619583 -1.3.1.8 * mycolicibacterium smegmatis 60000.0 2 PMID:6501266 -1.3.1.8 * nicotiana benthamiana 36270.0 1 PMID:16081072 -1.3.1.81 * mentha x piperita 45000.0 4 PMID:13679086;PMID:15542490 -1.3.1.82 * mentha x piperita 60000.0 3 PMID:13679086 -1.3.1.83 * arabidopsis thaliana 47000.0 1 PMID:9492312 -1.3.1.83 * prunus persica 51680.0 1 PMID:15286145 -1.3.1.84 * cereibacter sphaeroides 64000.0 1 PMID:23955006 -1.3.1.84 * escherichia coli 56000.0 1 PMID:23955006 -1.3.1.84 * metallosphaera sedula 40000.0 1 PMID:19429610 -1.3.1.84 * ruegeria pomeroyi 62000.0 1 PMID:23955006 -1.3.1.84 * sulfurisphaera tokodaii 43000.0 3 PMID:19429610 -1.3.1.85 * cereibacter sphaeroides 105000.0 2 PMID:17548827;PMID:19458256 -1.3.1.85 * cereibacter sphaeroides 2.4.1 105000.0 2 PMID:17548827;PMID:19458256 -1.3.1.85 * streptomyces sp. 143000.0 2 PMID:24915081 -1.3.1.86 * clostridioides difficile 110000.0 1 PMID:23772070 -1.3.1.86 * streptomyces collinus 85000.0 3 PMID:8521864 -1.3.1.87 * escherichia coli 28500.0 1 PMID:9603882 -1.3.1.9 * acinetobacter sp. rs1 28500.0 1 PMID:25019575 -1.3.1.9 * aliivibrio fischeri 43800.0 1 PMID:22232178 -1.3.1.9 * alistipes finegoldii 145000.0 2 PMID:32317282 -1.3.1.9 * brassica napus 348000.0 6 PMID:2194572;PMID:3732599 -1.3.1.9 * candidatus liberibacter asiaticus 61600.0 1 PMID:24407918 -1.3.1.9 * carthamus tinctorius 83000.0 1 PMID:7125663 -1.3.1.9 * eimeria tenella 35000.0 1 PMID:17697396 -1.3.1.9 * escherichia coli 120100.0 3 PMID:15491144;PMID:9022698 -1.3.1.9 * francisella tularensis 29968.0 1 PMID:21045289 -1.3.1.9 * listeria monocytogenes 28300.0 1 PMID:27736774 -1.3.1.9 * mycobacterium tuberculosis 115900.0 3 PMID:16647717;PMID:17600151;PMID:17996734 -1.3.1.9 * persea americana 62400.0 1 PMID:7075600 -1.3.1.9 * plasmodium falciparum 150000.0 3 PMID:15139852 -1.3.1.9 * spinacia oleracea 115000.0 2 PMID:6756317 -1.3.1.91 * saccharomyces cerevisiae 43000.0 1 PMID:19139092 -1.3.1.92 * artemisia annua 44000.0 1 PMID:18495659 -1.3.1.95 * anaerotignum propionicum 600000.0 3 PMID:12603323 -1.3.1.95 * clostridium kluyveri 28400.0 2 PMID:4063066 -1.3.1.95 * metallosphaera sedula 40000.0 1 PMID:19429610 -1.3.1.95 * sulfurisphaera tokodaii 43000.0 3 PMID:19429610 -1.3.1.96 * botryococcus braunii 52500.0 1 PMID:10620354 -1.3.1.97 * botryococcus braunii 52500.0 1 PMID:10620354;PMID:14725863 -1.3.1.98 * enterobacter cloacae 35500.0 1 PMID:36973;PMID:4717533 -1.3.1.98 * escherichia coli 38340.0 7 PMID:22068704;PMID:36973;PMID:4717533;PMID:7727397;PMID:8448160 -1.3.1.98 * mycobacterium tuberculosis 40000.0 1 * -1.3.1.98 * streptococcus pneumoniae 35000.0 1 PMID:11284731 -1.3.2.3 * arabidopsis thaliana 850000.0 7 PMID:18190525;PMID:22378782 -1.3.2.3 * brassica oleracea var. botrytis 56000.0 1 PMID:7775377;PMID:9374475 -1.3.2.3 * fragaria x ananassa 64570.0 2 * -1.3.2.3 * ipomoea batatas 56000.0 2 PMID:10050319;PMID:7775377;PMID:9374475 -1.3.2.3 * lotus japonicus 68800.0 1 PMID:16766673 -1.3.2.3 * nicotiana tabacum 56000.0 3 PMID:10945335;PMID:15549373 -1.3.3.10 * chromobacterium violaceum 680000.0 3 PMID:7559518;PMID:8027079 -1.3.3.10 * pseudomonas sp. 150000.0 1 PMID:7263628 -1.3.3.11 * deinococcus radiodurans 42000.0 1 PMID:14637137 -1.3.3.11 * escherichia coli 58000.0 4 PMID:17223081;PMID:18371220 -1.3.3.11 * klebsiella pneumoniae 58000.0 6 PMID:15148379;PMID:15211525;PMID:17523676;PMID:18371220;PMID:20602352 -1.3.3.11 * methylorubrum extorquens 300000.0 8 PMID:12437981;PMID:17223081 -1.3.3.11 * pseudomonas aeruginosa 58000.0 2 PMID:18371220 -1.3.3.12 * saccharomyces cerevisiae 290000.0 5 PMID:369458;PMID:6754380 -1.3.3.12 * trypanosoma cruzi 57000.0 1 PMID:17627608 -1.3.3.13 * streptomyces noursei 23000.0 3 PMID:11248691;PMID:12498889 -1.3.3.14 * streptomyces galilaeus 72000.0 1 PMID:528393 -1.3.3.15 * bacillus subtilis 56000.0 3 PMID:7928957;PMID:9217019;PMID:9784236 -1.3.3.17 * aromatoleum aromaticum 159000.0 1 PMID:34059946 -1.3.3.3 * bos taurus 74000.0 3 PMID:7372605;PMID:8407975;PMID:8547339;PMID:9251001 -1.3.3.3 * cereibacter sphaeroides 44000.0 1 PMID:4345352 -1.3.3.3 * chlamydomonas reinhardtii 35000.0 1 PMID:7889936 -1.3.3.3 * escherichia coli 70000.0 6 PMID:13129604;PMID:7768836 -1.3.3.3 * glycine max 37000.0 1 * -1.3.3.3 * homo sapiens 107000.0 10 PMID:11079369;PMID:16084099;PMID:16258391;PMID:16868543;PMID:24078084;PMID:9074788 -1.3.3.3 * lotus japonicus 37000.0 1 PMID:8407975;PMID:8547339;PMID:9251001 -1.3.3.3 * mus musculus 70000.0 3 PMID:2540974;PMID:3516695;PMID:8407975;PMID:8547339;PMID:9251001;PMID:9251002 -1.3.3.3 * plasmodium falciparum 61000.0 3 PMID:20006984 -1.3.3.3 * rattus sp. 80000.0 3 PMID:11079369;PMID:5881662;PMID:9074788 -1.3.3.3 * saccharomyces cerevisiae 75000.0 7 PMID:15194705;PMID:2540974;PMID:2838478;PMID:3516695;PMID:4153629;PMID:9251002 -1.3.3.3 * synechocystis sp. 40300.0 1 PMID:20194361 -1.3.3.3 * vigna radiata var. radiata 37000.0 1 PMID:8407975;PMID:8547339;PMID:9251001 -1.3.3.4 * bacillus subtilis 56000.0 3 PMID:9217019;PMID:9784236 -1.3.3.4 * bos taurus 57000.0 1 PMID:2439126 -1.3.3.4 * chlamydomonas reinhardtii 59800.0 3 PMID:16306143 -1.3.3.4 * homo sapiens 100000.0 6 PMID:11929051;PMID:12922165;PMID:18437505;PMID:4051500;PMID:8621504;PMID:8771201;PMID:9074790 -1.3.3.4 * hordeum vulgare 210000.0 2 PMID:3663113 -1.3.3.4 * megalodesulfovibrio gigas 148000.0 4 PMID:3667528 -1.3.3.4 * mus musculus 65000.0 1 PMID:3606986 -1.3.3.4 * myxococcus xanthus 100000.0 5 PMID:8621504;PMID:8771201;PMID:9074790 -1.3.3.4 * nicotiana tabacum 59000.0 3 PMID:15057273;PMID:9238074 -1.3.3.4 * rattus norvegicus 33000.0 1 PMID:6461 -1.3.3.4 * saccharomyces cerevisiae 180000.0 3 PMID:234450;PMID:7798202;PMID:8621563 -1.3.3.4 * spinacia oleracea 60000.0 3 PMID:10965946;PMID:10982422 -1.3.3.5 * albifimbria verrucaria 68100.0 10 PMID:10074356;PMID:15802224;PMID:19914582;PMID:20852807;PMID:22862914;PMID:8360171 -1.3.3.5 * bacillus pumilus 61006.0 2 PMID:22410485 -1.3.3.5 * myrothecium sp. 62000.0 1 PMID:17884654 -1.3.3.5 * pyricularia oryzae 63975.0 2 PMID:22350257 -1.3.3.6 * arabidopsis thaliana 660000.0 11 PMID:10571860;PMID:18272379 -1.3.3.6 * arthrobacter sp. 76400.0 1 PMID:17141592 -1.3.3.6 * candida tropicalis 600000.0 4 PMID:518611;PMID:6615798;PMID:6639056 -1.3.3.6 * cucumis sativus 150000.0 2 PMID:3087978 -1.3.3.6 * cucurbita sp. 73000.0 1 PMID:9525937 -1.3.3.6 * glutamicibacter nicotianae 100000.0 2 * -1.3.3.6 * homo sapiens 81000.0 4 PMID:17603022;PMID:20185470;PMID:7876265 -1.3.3.6 * paenarthrobacter ureafaciens 190000.0 7 PMID:17141592 -1.3.3.6 * rattus norvegicus 427000.0 12 PMID:18061544;PMID:2156865;PMID:7400120;PMID:7417271 -1.3.3.6 * spraguea lophii 72000.0 1 PMID:16004370 -1.3.3.6 * zea mays 62000.0 3 PMID:8973574 -1.3.3.7 * rhodotorula glutinis 80000.0 1 * -1.3.3.8 * berberis stolonifera 100000.0 1 * -1.3.3.8 * berberis wilsoniae 100000.0 1 * -1.3.3.8 * coptis japonica 155000.0 6 PMID:2463630 -1.3.3.8 * thalictrum minus var. hypoleucum 200000.0 3 * -1.3.4.1 * methanothermobacter thermautotrophicus 78000.0 2 PMID:2499256 -1.3.5.1 * acidianus ambivalens 67000.0 4 PMID:11178972 -1.3.5.1 * ascaris suum 120000.0 5 PMID:3753651;PMID:7822332 -1.3.5.1 * bacillus subtilis 65000.0 2 PMID:108258 -1.3.5.1 * bos taurus 105000.0 6 PMID:16120479;PMID:4326769 -1.3.5.1 * chloroflexus aurantiacus 260000.0 7 PMID:19103151 -1.3.5.1 * corynebacterium glutamicum 410000.0 5 PMID:15883782 -1.3.5.1 * desulfobulbus elongatus 170000.0 2 PMID:3582662 -1.3.5.1 * escherichia coli 360000.0 15 PMID:12560550;PMID:12788489;PMID:2991245;PMID:3008149;PMID:383238;PMID:6751504;PMID:9092498 -1.3.5.1 * glycine max 67000.0 4 PMID:16662722 -1.3.5.1 * halobacterium salinarum 100000.0 1 PMID:4004256 -1.3.5.1 * ipomoea batatas 110000.0 3 * -1.3.5.1 * mammalia 105000.0 2 PMID:713837 -1.3.5.1 * micrococcus luteus 72000.0 3 PMID:6402500 -1.3.5.1 * mus musculus 68000.0 4 PMID:16120479 -1.3.5.1 * mycolicibacterium phlei 62000.0 2 PMID:3722123 -1.3.5.1 * neurospora crassa 72000.0 3 PMID:226365 -1.3.5.1 * paracoccus denitrificans 65600.0 4 PMID:9639600 -1.3.5.1 * plasmodium yoelii yoelii 135000.0 4 PMID:19060309 -1.3.5.1 * rattus norvegicus 70000.0 1 PMID:17997986 -1.3.5.1 * rhodospirillum rubrum 180000.0 3 PMID:199588;PMID:406851;PMID:4344128 -1.3.5.1 * rhodothermus marinus 70000.0 3 PMID:11710809 -1.3.5.1 * saccharomyces cerevisiae 150000.0 8 PMID:11803020;PMID:18279395;PMID:23043141 -1.3.5.1 * schistosoma japonicum 32000.0 1 PMID:17447029 -1.3.5.1 * sulfolobus acidocaldarius 141000.0 9 PMID:1935955;PMID:9287013 -1.3.5.1 * sulfolobus sp. 66000.0 4 PMID:8537344 -1.3.5.1 * sulfurisphaera tokodaii 63000.0 1 PMID:24566086 -1.3.5.1 * thermus thermophilus 500000.0 10 PMID:20951673;PMID:23308253 -1.3.5.1 * vigna radiata 67000.0 4 PMID:16662722 -1.3.5.1 * wolinella succinogenes 200000.0 19 PMID:11532445;PMID:2856137;PMID:7333282;PMID:7397125 -1.3.5.2 * arabidopsis thaliana 48500.0 1 PMID:12372626 -1.3.5.2 * bos taurus 42000.0 1 PMID:3733756 -1.3.5.2 * candida albicans 48000.0 1 PMID:16774642 -1.3.5.2 * enterococcus faecalis 80000.0 2 PMID:10775458 -1.3.5.2 * escherichia coli 75000.0 6 PMID:10074342;PMID:211391 -1.3.5.2 * homo sapiens 130000.0 9 PMID:11248707;PMID:7487077;PMID:8925840;PMID:9313772 -1.3.5.2 * neurospora crassa 210000.0 1 PMID:211392 -1.3.5.2 * plasmodium falciparum 56000.0 2 PMID:7727509 -1.3.5.2 * rattus norvegicus 45100.0 2 PMID:9693067 -1.3.5.2 * toxoplasma gondii 47000.0 1 PMID:23747278 -1.3.5.2 * trypanosoma cruzi 35000.0 2 PMID:12106873 -1.3.5.3 * escherichia coli 150000.0 4 PMID:19583219;PMID:20484676 -1.3.5.5 * brassica oleracea 660000.0 3 PMID:18298413 -1.3.5.5 * oryza sativa indica group 450000.0 1 PMID:26147209 -1.3.5.5 * triticum aestivum 643300.0 1 PMID:20013057 -1.3.5.6 * auxenochlorella protothecoides 63700.0 1 PMID:22013384 -1.3.5.6 * capsicum annuum 60000.0 1 PMID:10491195 -1.3.5.6 * dunaliella salina 63900.0 1 * -1.3.7.1 * eubacterium barkeri 53000.0 1 PMID:16894175 -1.3.7.11 * archaeoglobus fulgidus 46978.0 2 PMID:17288560 -1.3.7.11 * thermoplasma acidophilum 43400.0 1 PMID:20869368 -1.3.7.12 * arabidopsis thaliana 60000.0 6 PMID:19374909 -1.3.7.12 * hordeum vulgare 58000.0 2 PMID:10743659 -1.3.7.15 * roseobacter denitrificans 56000.0 2 PMID:25422320 -1.3.7.2 * synechococcus sp. 28000.0 1 PMID:11283349 -1.3.7.3 * synechococcus sp. 30300.0 1 PMID:11283349 -1.3.7.4 * arabidopsis thaliana 38100.0 3 PMID:11226195;PMID:11283349 -1.3.7.4 * avena sativa 29000.0 1 PMID:11500553 -1.3.7.5 * anabaena sp. 30400.0 3 PMID:11283349;PMID:12514179 -1.3.7.5 * synechocystis sp. 28900.0 1 PMID:11283349 -1.3.7.5 * thermosynechococcus vestitus 27000.0 1 PMID:19328793 -1.3.7.7 * auxenochlorella protothecoides 58000.0 3 PMID:16889380 -1.3.7.7 * cereibacter sphaeroides 33380.0 2 PMID:19006326 -1.3.7.7 * leptolyngbya boryana 58000.0 2 PMID:8673341 -1.3.7.7 * prochlorococcus marinus 360000.0 6 PMID:20075073 -1.3.7.7 * rhodobacter capsulatus 200000.0 14 PMID:10811655;PMID:15953479 -1.3.7.8 * desulfosarcina cetonica 956000.0 2 PMID:31430028 -1.3.7.8 * thauera aromatica 170000.0 6 PMID:29769313;PMID:8575453 -1.3.7.8 * thauera chlorobenzoica 152000.0 2 PMID:29769313 -1.3.8.1 * bos taurus 220000.0 5 PMID:13130521;PMID:6546382;PMID:6712627 -1.3.8.1 * butyrivibrio fibrisolvens 42840.0 2 PMID:15991056 -1.3.8.1 * clostridioides difficile 110000.0 1 PMID:23772070 -1.3.8.1 * clostridium acetobutylicum 90000.0 1 PMID:9009069 -1.3.8.1 * clostridium kluyveri 28400.0 2 PMID:4063066 -1.3.8.1 * homo sapiens 168000.0 3 PMID:16331963;PMID:16331964;PMID:3597357 -1.3.8.1 * megasphaera elsdenii 155000.0 3 PMID:3790549;PMID:5145910 -1.3.8.1 * mus musculus 44000.0 2 PMID:18500942 -1.3.8.1 * pseudomonas putida 160000.0 4 PMID:16024185;PMID:3968063 -1.3.8.1 * rattus norvegicus 169000.0 5 PMID:16024185;PMID:2777793;PMID:3813556;PMID:3968063;PMID:6489337;PMID:7334008 -1.3.8.1 * sus scrofa 220000.0 1 PMID:13130522 -1.3.8.10 * syntrophus aciditrophicus 150000.0 1 PMID:23667239 -1.3.8.11 * syntrophus aciditrophicus 155000.0 3 PMID:23667239 -1.3.8.12 * cereibacter sphaeroides 100000.0 2 PMID:19703103 -1.3.8.13 * escherichia coli 164400.0 2 PMID:10209289 -1.3.8.13 * proteus sp. (in: enterobacteria) 166000.0 2 PMID:15731894 -1.3.8.16 * streptomyces globisporus 29100.0 1 PMID:18182490 -1.3.8.2 * staphylococcus aureus 52000.0 1 PMID:10498735 -1.3.8.3 * thauera aromatica 200000.0 2 PMID:12420174 -1.3.8.4 * arabidopsis thaliana 107000.0 2 PMID:11402190 -1.3.8.4 * caenorhabditis elegans 43000.0 1 PMID:11386848;PMID:2853821;PMID:6401713 -1.3.8.4 * homo sapiens 172000.0 4 PMID:10713113;PMID:15574432;PMID:3597357 -1.3.8.4 * pseudomonas aeruginosa 163000.0 3 PMID:18625020 -1.3.8.4 * rattus norvegicus 175000.0 3 PMID:11386848;PMID:2777793;PMID:2853821;PMID:6401713 -1.3.8.4 * solanum tuberosum 146000.0 3 PMID:11231285;PMID:15574432 -1.3.8.5 * ascaris suum 170000.0 4 PMID:2853820;PMID:3988734;PMID:6874697;PMID:7693666;PMID:9566523 -1.3.8.5 * rattus norvegicus 170000.0 2 PMID:2853820;PMID:3988734;PMID:6874697 -1.3.8.5 * solanum tuberosum 188000.0 2 PMID:15574432 -1.3.8.6 * azoarcus sp. 45000.0 1 PMID:18177371 -1.3.8.6 * bos taurus 200000.0 1 PMID:4304226 -1.3.8.6 * homo sapiens 256000.0 3 PMID:12948740;PMID:3081514 -1.3.8.6 * paracoccus denitrificans 180000.0 2 PMID:2991202 -1.3.8.6 * pseudomonas sp. 170000.0 2 PMID:8439237 -1.3.8.6 * sus scrofa 190500.0 2 PMID:3081514 -1.3.8.7 * bos taurus 205000.0 3 PMID:6546382;PMID:713854 -1.3.8.7 * homo sapiens 178000.0 4 PMID:16020546;PMID:3597357;PMID:7578106 -1.3.8.7 * rattus norvegicus 182000.0 7 PMID:15358373;PMID:18061544;PMID:2777793;PMID:3611054;PMID:3968063;PMID:7334008;PMID:7354088 -1.3.8.7 * sus scrofa 183000.0 6 PMID:1168197;PMID:3968063;PMID:570409;PMID:713854;PMID:7278659;PMID:7354088 -1.3.8.8 * acinetobacter sp. 135000.0 3 PMID:16233311 -1.3.8.8 * bos taurus 172000.0 1 PMID:6546382 -1.3.8.8 * homo sapiens 180000.0 6 PMID:15731883;PMID:16621643;PMID:17374501;PMID:3968063;PMID:9182995 -1.3.8.8 * mus musculus 44000.0 2 PMID:15731883;PMID:18720429 -1.3.8.8 * rattus norvegicus 180000.0 3 PMID:2777793;PMID:3968063;PMID:7334008;PMID:9182995 -1.3.8.8 * sus scrofa 200000.0 2 PMID:13319294;PMID:9182995 -1.3.8.9 * caenorhabditis elegans 180000.0 1 PMID:20383014 -1.3.98.1 * crithidia fasciculata 63300.0 4 PMID:4366023;PMID:5547979;PMID:6087880;PMID:6299333 -1.3.98.1 * lactobacillus delbrueckii subsp. bulgaricus 57000.0 3 PMID:4366023;PMID:5547979;PMID:6299333 -1.3.98.1 * lactococcus lactis 67000.0 3 PMID:12381841;PMID:8732756 -1.3.98.1 * leishmania major 63200.0 2 PMID:16600626 -1.3.98.1 * neobodo saliens 70000.0 2 PMID:17475213 -1.3.98.1 * plasmodium falciparum 50000.0 1 PMID:16510978 -1.3.98.1 * rattus norvegicus 61000.0 1 PMID:199900 -1.3.98.1 * saccharomyces cerevisiae 72000.0 4 PMID:10871048;PMID:17617217 -1.3.98.1 * toxoplasma gondii 66200.0 2 PMID:12633907 -1.3.98.1 * trypanosoma brucei brucei 62000.0 2 PMID:6299333 -1.3.98.1 * trypanosoma cruzi 70000.0 7 PMID:12106873;PMID:16172019 -1.3.98.3 * escherichia coli 52000.0 1 PMID:12114526 -1.3.98.3 * vibrio vulnificus 55000.0 1 PMID:25626927 -1.3.98.5 * listeria monocytogenes serotype 1/2a 180000.0 2 PMID:25602700 -1.3.99.16 * brevundimonas diminuta 95000.0 5 PMID:7782304;PMID:8157655 -1.3.99.17 * comamonas testosteroni 360000.0 4 PMID:7556204 -1.3.99.17 * pseudomonas putida 300000.0 7 PMID:2090161 -1.3.99.17 * rhodococcus sp. (in: high g+c gram-positive bacteria) 310000.0 5 PMID:1789933 -1.3.99.18 * pseudomonas sp. 300000.0 4 PMID:8292263 -1.3.99.18 * serratia marcescens 100000.0 1 PMID:8357532 -1.3.99.19 * agrobacterium sp. 320000.0 4 PMID:1418685 -1.3.99.23 * homo sapiens 60000.0 1 PMID:19139408 -1.3.99.23 * mus musculus 67000.0 2 PMID:19139408;PMID:32345479 -1.3.99.27 * cereibacter sphaeroides 58000.0 1 PMID:9393712 -1.3.99.27 * uncultured marine bacterium 55000.0 1 PMID:15251462 -1.3.99.28 * cereibacter azotoformans 57000.0 1 PMID:22640029 -1.3.99.28 * rhodobacter capsulatus 60000.0 2 PMID:2546948;PMID:8830054 -1.3.99.29 * auxenochlorella protothecoides 61000.0 1 PMID:23271125 -1.3.99.30 * neurospora crassa 62000.0 1 PMID:11017770 -1.3.99.31 * cereibacter azotoformans 57000.0 1 PMID:22640029 -1.3.99.31 * pantoea ananatis 56200.0 1 PMID:1400305 -1.3.99.33 * shewanella oneidensis 60200.0 2 PMID:23078170 -1.3.99.4 * aspergillus fumigatus 64370.0 1 PMID:22234537 -1.3.99.4 * gordonia rubripertincta 60500.0 1 PMID:2317517 -1.3.99.4 * pimelobacter simplex 55000.0 3 PMID:17451526;PMID:8586617;PMID:8590655 -1.3.99.4 * rhodococcus erythropolis 61000.0 4 PMID:18031290;PMID:22691786 -1.3.99.4 * rhodococcus rhodochrous 55000.0 1 PMID:9792929 -1.3.99.41 * ruegeria pomeroyi 62854.0 1 PMID:21562561 -1.3.99.5 * comamonas testosteroni 60000.0 2 PMID:8655514 -1.3.99.6 * [clostridium] innocuum 80000.0 1 PMID:3861198 -1.3.99.6 * comamonas testosteroni 32000.0 1 PMID:5907467 -1.3.99.6 * rattus norvegicus 37000.0 1 PMID:8550030 -1.3.99.8 * pseudomonas putida 3270000.0 6 PMID:16347977;PMID:2170335;PMID:4655411 -1.4.1.1 * alkalihalophilus pseudofirmus 166100.0 1 PMID:24192355 -1.4.1.1 * anabaena cylindrica 270000.0 2 PMID:10473410;PMID:4043 -1.4.1.1 * archaeoglobus fulgidus 76000.0 2 PMID:15516582 -1.4.1.1 * bacillus cereus 255000.0 2 PMID:11041346;PMID:2722749;PMID:3104322 -1.4.1.1 * bacillus japonicum 190000.0 1 PMID:7705101 -1.4.1.1 * bacillus subtilis 280000.0 3 PMID:14298830;PMID:19720515;PMID:4204435 -1.4.1.1 * bacteria 260000.0 2 PMID:11453464;PMID:12664266 -1.4.1.1 * bilophila wadsworthia 273000.0 3 PMID:11041346;PMID:2722749;PMID:3104322 -1.4.1.1 * bradyrhizobium japonicum 168000.0 2 * -1.4.1.1 * geobacillus stearothermophilus 240000.0 2 * -1.4.1.1 * halobacterium salinarum 72500.0 3 PMID:486498;PMID:849265 -1.4.1.1 * kitasatospora aureofaciens 395000.0 3 PMID:2501471 -1.4.1.1 * klebsiella aerogenes 245000.0 3 PMID:9972262 -1.4.1.1 * lysinibacillus sphaericus 235000.0 6 PMID:2340274;PMID:2390993;PMID:488097 -1.4.1.1 * mycobacterium tuberculosis 40000.0 3 PMID:17053316;PMID:18304579;PMID:18491387 -1.4.1.1 * phormidium lapideum 240000.0 2 PMID:7896761 -1.4.1.1 * priestia megaterium 42500.0 2 PMID:12375815;PMID:23908047 -1.4.1.1 * pseudomonas sp. 217000.0 2 PMID:3446176 -1.4.1.1 * rhodobacter capsulatus 246000.0 3 PMID:11041346;PMID:2722749;PMID:3104322 -1.4.1.1 * shewanella sp. 260000.0 3 PMID:10473410;PMID:11453464;PMID:12664266;PMID:4043 -1.4.1.1 * streptomyces clavuligerus 92000.0 1 PMID:7387330 -1.4.1.1 * streptomyces fradiae 210000.0 2 PMID:2917562 -1.4.1.1 * streptomyces phaeochromogenes 240000.0 2 PMID:7896761 -1.4.1.1 * thermus thermophilus 290000.0 2 PMID:6775703 -1.4.1.1 * vibrio proteolyticus 230000.0 2 PMID:2390993;PMID:488097;PMID:9972262 -1.4.1.11 * brevibacterium l5 71000.0 1 PMID:4692842 -1.4.1.11 * clostridium sp. 135000.0 4 PMID:4344229 -1.4.1.12 * acetoanaerobium sticklandii 80000.0 6 PMID:19251850;PMID:4684685 -1.4.1.13 * amycolatopsis mediterranei 195000.0 3 PMID:3350793 -1.4.1.13 * azospirillum brasilense 800000.0 7 PMID:10785395;PMID:18199747;PMID:4019412 -1.4.1.13 * bacillus licheniformis 220000.0 3 PMID:6501215 -1.4.1.13 * bacillus subtilis 210000.0 3 PMID:3011766 -1.4.1.13 * clostridium saccharobutylicum 46000.0 1 PMID:14732492 -1.4.1.13 * escherichia coli 800000.0 3 PMID:4565085 -1.4.1.13 * geobacillus stearothermophilus 160000.0 1 PMID:6102851 -1.4.1.13 * gluconobacter oxydans 500000.0 1 * -1.4.1.13 * klebsiella aerogenes 175000.0 2 PMID:3911003 -1.4.1.13 * priestia megaterium 840000.0 3 PMID:99144 -1.4.1.13 * pseudomonas aeruginosa 160000.0 1 PMID:6102851 -1.4.1.13 * pyrococcus horikoshii 52400.0 3 PMID:20630732 -1.4.1.13 * pyrococcus sp. 205000.0 2 PMID:9202379 -1.4.1.13 * rhodospirillum rubrum 840000.0 5 PMID:1930133 -1.4.1.13 * salmonella enterica subsp. enterica serovar typhimurium 170000.0 1 PMID:16820760 -1.4.1.13 * thiobacillus thioparus 280000.0 3 PMID:14919 -1.4.1.14 * arabidopsis thaliana 240000.0 2 PMID:11844111;PMID:19555410 -1.4.1.14 * chlamydomonas reinhardtii 240000.0 1 * -1.4.1.14 * clostridium pasteurianum 590000.0 6 PMID:2611221 -1.4.1.14 * lupinus angustifolius 235000.0 1 PMID:21790 -1.4.1.14 * medicago sativa 235000.0 3 PMID:16666762;PMID:2943726;PMID:7550373 -1.4.1.14 * neurospora crassa 200000.0 1 PMID:16666762;PMID:2943726 -1.4.1.14 * oryza sativa 236700.0 3 PMID:16668794 -1.4.1.14 * phaseolus vulgaris 241000.0 3 PMID:16666475;PMID:18182018 -1.4.1.14 * saccharomyces cerevisiae 265000.0 3 PMID:3911003;PMID:7047525 -1.4.1.14 * vicia faba 236000.0 3 * -1.4.1.16 * brevibacterium sp. 70000.0 2 * -1.4.1.16 * corynebacterium glutamicum 70000.0 4 PMID:8865347 -1.4.1.16 * lysinibacillus sphaericus 80000.0 3 PMID:7430138 -1.4.1.16 * thermosyntropha lipolytica 220000.0 1 PMID:32599299 -1.4.1.16 * ureibacillus thermosphaericus 80000.0 2 PMID:22117688 -1.4.1.17 * pseudomonas sp. 77000.0 2 PMID:236301 -1.4.1.18 * achromobacter denitrificans 80000.0 3 PMID:19017491 -1.4.1.18 * agrobacterium tumefaciens 165000.0 2 PMID:2768207 -1.4.1.18 * anabasis aphylla 100000.0 1 * -1.4.1.18 * geobacillus stearothermophilus 42239.0 1 PMID:14766574 -1.4.1.18 * pyrococcus horikoshii 97200.0 3 PMID:20056607 -1.4.1.19 * nostoc punctiforme 76100.0 1 PMID:24835098 -1.4.1.2 * [clostridium] symbiosum 48000.0 1 PMID:23761034 -1.4.1.2 * achlya sp. (in: oomycetes) 225000.0 1 * -1.4.1.2 * agaricus bisporus 474000.0 2 PMID:10323225;PMID:7190566;PMID:9454644 -1.4.1.2 * alicyclobacillus acidocaldarius 290000.0 2 * -1.4.1.2 * amphibacillus xylanus 260000.0 2 PMID:8424683;PMID:8836445 -1.4.1.2 * ancylobacter novellus 130000.0 1 * -1.4.1.2 * aspergillus nidulans 670000.0 1 PMID:2524418 -1.4.1.2 * bacillus cereus 270000.0 3 PMID:16244435;PMID:828900;PMID:8515235 -1.4.1.2 * bacillus subtilis 270000.0 6 PMID:16195607;PMID:16244435;PMID:17608797;PMID:8515235 -1.4.1.2 * benjaminiella poitrasii 371000.0 1 PMID:23588417 -1.4.1.2 * blastocladiella emersonii 250000.0 1 * -1.4.1.2 * bos taurus 330000.0 2 PMID:7588764 -1.4.1.2 * chlorella sorokiniana 180000.0 2 PMID:16660436 -1.4.1.2 * clostridioides difficile 300000.0 7 PMID:1774279;PMID:24145018;PMID:8424683;PMID:8836445 -1.4.1.2 * clostridium botulinum 250800.0 2 PMID:3061371 -1.4.1.2 * clostridium sp. 390000.0 2 * -1.4.1.2 * crithidia fasciculata 380000.0 1 * -1.4.1.2 * cyberlindnera jadinii 460000.0 2 PMID:10323225;PMID:7190566;PMID:9454644 -1.4.1.2 * dictyostelium discoideum 356000.0 2 PMID:1952936 -1.4.1.2 * entodinium caudatum 48000.0 1 PMID:15921862 -1.4.1.2 * globisporangium debaryanum 225000.0 1 * -1.4.1.2 * haloferax mediterranei 310000.0 4 PMID:16200391 -1.4.1.2 * janthinobacterium lividum 170000.0 2 PMID:17526698 -1.4.1.2 * laccaria bicolor 470000.0 2 PMID:10323225;PMID:7190566;PMID:9454644 -1.4.1.2 * lathyrus oleraceus 230000.0 3 PMID:7385942 -1.4.1.2 * lemna minor 230000.0 2 PMID:7385942 -1.4.1.2 * lupinus luteus 270000.0 2 PMID:16244435;PMID:8424683;PMID:8515235;PMID:8836445 -1.4.1.2 * neurospora crassa 480000.0 5 PMID:4372225;PMID:4399934 -1.4.1.2 * peptoniphilus asaccharolyticus 270000.0 4 PMID:16244435;PMID:23761034;PMID:4338318;PMID:6502134;PMID:8515235 -1.4.1.2 * phycomyces blakesleeanus 98000.0 2 PMID:3221200 -1.4.1.2 * psychrobacter sp. 300000.0 4 PMID:11867281;PMID:8424683 -1.4.1.2 * pyrobaculum calidifontis 286000.0 1 PMID:23508687 -1.4.1.2 * pyrobaculum islandicum 337000.0 7 PMID:10525154;PMID:16285734;PMID:22972344;PMID:9603828 -1.4.1.2 * pyrococcus sp. 284000.0 2 * -1.4.1.2 * salinibacter ruber 226000.0 2 PMID:13129625 -1.4.1.2 * sporosarcina ureae 250000.0 2 * -1.4.1.2 * streptomyces clavuligerus 1100000.0 2 PMID:10924516 -1.4.1.2 * synechocystis sp. 295000.0 2 PMID:1906012 -1.4.1.2 * thermus thermophilus 289000.0 2 * -1.4.1.2 * vitis vinifera 252000.0 2 PMID:3061371 -1.4.1.20 * dietzia maris 70000.0 2 PMID:2536657 -1.4.1.20 * lysinibacillus sphaericus 380000.0 9 PMID:12234181;PMID:14622249;PMID:2838396;PMID:3112142;PMID:9477256 -1.4.1.20 * microbacterium sp. 330000.0 2 PMID:9477256 -1.4.1.20 * nocardia sp. 42000.0 1 * -1.4.1.20 * pseudobacillus badius 720000.0 5 PMID:16215831;PMID:3311741 -1.4.1.20 * rhodococcus sp. (in: high g+c gram-positive bacteria) 150000.0 2 PMID:10924111 -1.4.1.20 * sporosarcina ureae 310000.0 4 PMID:3112142 -1.4.1.20 * thermoactinomyces intermedius 72000.0 3 PMID:7883771;PMID:8407879 -1.4.1.21 * archaeoglobus fulgidus 48000.0 4 PMID:16731057;PMID:22120624 -1.4.1.21 * cupriavidus necator 28000.0 2 PMID:21821928;PMID:22120624 -1.4.1.21 * klebsiella pneumoniae 124000.0 3 PMID:22120624;PMID:9819709 -1.4.1.21 * pseudomonas aeruginosa 60000.0 4 PMID:21468714;PMID:22120624 -1.4.1.21 * thermotoga maritima 27000.0 1 PMID:22120624 -1.4.1.23 * alcaligenes faecalis 72000.0 2 PMID:8448188 -1.4.1.23 * kitasatospora aureofaciens 240000.0 6 PMID:3182727;PMID:7669808 -1.4.1.23 * streptomyces coelicolor 70000.0 2 PMID:2324704;PMID:2803248 -1.4.1.23 * streptomyces fradiae 218000.0 4 PMID:2324704;PMID:2803248;PMID:3269392 -1.4.1.23 * streptomyces virginiae 88000.0 2 PMID:2324704;PMID:2803248 -1.4.1.27 * arabidopsis thaliana 1650000.0 1 PMID:32311173 -1.4.1.27 * gallus gallus 220000.0 5 PMID:4648867;PMID:7053363;PMID:7440562 -1.4.1.27 * lathyrus oleraceus 1650000.0 1 PMID:32311173 -1.4.1.27 * rattus norvegicus 210000.0 1 PMID:6778858 -1.4.1.27 * synechocystis sp. pcc 6803 200000.0 3 PMID:32311173 -1.4.1.28 * streptomyces virginiae 95000.0 1 * -1.4.1.3 * acholeplasma laidlawii 260000.0 1 * -1.4.1.3 * anguilla anguilla 340000.0 2 PMID:1639763 -1.4.1.3 * azospirillum brasilense 285000.0 2 PMID:12590923;PMID:3956501 -1.4.1.3 * bacillus subtilis 270000.0 2 PMID:14949 -1.4.1.3 * bacteroides fragilis 350000.0 3 PMID:3667555 -1.4.1.3 * bos taurus 350000.0 3 PMID:11235914;PMID:14659072 -1.4.1.3 * chlamydomonas reinhardtii 269000.0 3 PMID:1540636 -1.4.1.3 * dogfish 350000.0 1 PMID:35153 -1.4.1.3 * gallus gallus 350000.0 1 * -1.4.1.3 * glycine max 350000.0 1 PMID:7197901 -1.4.1.3 * homo sapiens 336000.0 5 PMID:15044002;PMID:17253646;PMID:19428807 -1.4.1.3 * pyrococcus 284000.0 2 PMID:9520268 -1.4.1.3 * pyrococcus furiosus 270000.0 5 PMID:1576153;PMID:1899341;PMID:1901040;PMID:7887598;PMID:8060497;PMID:8349661 -1.4.1.3 * pyrococcus horikoshii 290000.0 2 PMID:12590923;PMID:3956501 -1.4.1.3 * pyrococcus sp. 270000.0 2 PMID:1576153;PMID:1899341;PMID:1901040;PMID:8349661 -1.4.1.3 * rattus norvegicus 350000.0 3 PMID:10618641;PMID:17949437;PMID:35153 -1.4.1.3 * saccharolobus solfataricus 270000.0 5 PMID:10774743;PMID:1576153;PMID:1730244;PMID:1899341;PMID:1901040;PMID:8349661;PMID:8399381 -1.4.1.3 * salinibacter ruber 460000.0 2 PMID:13129625 -1.4.1.3 * sphagnum fallax 210000.0 2 * -1.4.1.3 * sus scrofa 350000.0 4 * -1.4.1.3 * tenebrio molitor 340000.0 2 PMID:1639763 -1.4.1.3 * thermococcus kodakarensis 284000.0 3 PMID:9434762 -1.4.1.3 * thermococcus profundus 46000.0 1 PMID:11258921 -1.4.1.3 * thermus thermophilus 331000.0 3 PMID:18545996;PMID:31036724 -1.4.1.3 * thunnus thynnus 350000.0 3 PMID:182270;PMID:35153 -1.4.1.3 * uncultured bacterium 250500.0 2 PMID:22360886 -1.4.1.3 * urocitellus richardsonii 335000.0 3 PMID:11235914 -1.4.1.4 * acinetobacter lwoffii 250000.0 2 PMID:19933355 -1.4.1.4 * acropora formosa 360000.0 2 PMID:8914269 -1.4.1.4 * aeropyrum pernix 270000.0 4 PMID:11139075;PMID:23508687;PMID:9538867 -1.4.1.4 * aeropyrum pernix k1 285000.0 5 PMID:10601858;PMID:11139075;PMID:11265455;PMID:11265468;PMID:11549007;PMID:7763882;PMID:9190263;PMID:99144 -1.4.1.4 * agaricus bisporus 330000.0 2 PMID:2543290;PMID:34271431;PMID:7765894 -1.4.1.4 * archaeoglobus fulgidus 263000.0 2 PMID:10601858;PMID:11265455;PMID:11549007;PMID:7763882;PMID:9385147;PMID:99144 -1.4.1.4 * aspergillus niger 350000.0 2 PMID:15870451;PMID:8135516 -1.4.1.4 * aspergillus terreus 350000.0 2 PMID:19619653 -1.4.1.4 * bacillus sp. (in: firmicutes) 315000.0 2 PMID:1656203 -1.4.1.4 * benjaminiella poitrasii 298000.0 2 PMID:32768460 -1.4.1.4 * bryopsis maxima 280000.0 2 PMID:11139075;PMID:27404;PMID:3139639;PMID:4144743;PMID:9190263 -1.4.1.4 * candida albicans 330000.0 1 PMID:34271431;PMID:7765894 -1.4.1.4 * chlorella sorokiniana 55500.0 2 PMID:16665219 -1.4.1.4 * corallomycetella repens 280000.0 2 PMID:2543290;PMID:7765894 -1.4.1.4 * dictyostelium discoideum 294000.0 2 PMID:1656203 -1.4.1.4 * escherichia coli 300000.0 6 PMID:235298;PMID:241744 -1.4.1.4 * geotrichum candidum 223000.0 1 PMID:28050850 -1.4.1.4 * giardia duodenalis 270000.0 3 PMID:11139075;PMID:23508687;PMID:9538867 -1.4.1.4 * halobacterium sp. 212000.0 2 PMID:708691 -1.4.1.4 * haloferax mediterranei 320000.0 4 PMID:9064251 -1.4.1.4 * klebsiella pneumoniae 300000.0 2 PMID:16233253;PMID:7763882 -1.4.1.4 * leptolyngbya laminosa 280000.0 1 PMID:27404;PMID:3139639;PMID:4144743;PMID:9190263 -1.4.1.4 * limosilactobacillus fermentum 300000.0 2 PMID:16233253;PMID:241744;PMID:7763882 -1.4.1.4 * metabacillus fastidiosus 48000.0 1 PMID:2543290;PMID:7765894 -1.4.1.4 * mycolicibacterium smegmatis 245500.0 2 PMID:7417453 -1.4.1.4 * nitrobacter hamburgensis 310000.0 2 PMID:2543290;PMID:7765894 -1.4.1.4 * penicillium chrysogenum 339000.0 2 PMID:8914269 -1.4.1.4 * phaffia rhodozyma 49000.0 1 PMID:19016007 -1.4.1.4 * plasmodium falciparum 300000.0 3 PMID:22342964 -1.4.1.4 * priestia megaterium 270000.0 2 PMID:10601858;PMID:11265455;PMID:11549007;PMID:7763882;PMID:99144 -1.4.1.4 * proteus inconstans 400000.0 2 * -1.4.1.4 * pseudomonas aeruginosa 170000.0 2 PMID:19933355 -1.4.1.4 * psychrobacter sp. 300000.0 4 PMID:10601858;PMID:11265455;PMID:11549007;PMID:16233253;PMID:7763882;PMID:99144 -1.4.1.4 * pyrobaculum calidifontis 270000.0 1 PMID:11139075;PMID:23508687;PMID:9538867 -1.4.1.4 * pyrococcus furiosus 300000.0 3 PMID:10601858;PMID:11265455;PMID:11549007;PMID:16233253;PMID:1765079;PMID:7763882;PMID:99144 -1.4.1.4 * pyrococcus woesei 300000.0 2 PMID:10601858;PMID:11265455;PMID:11549007;PMID:16233253;PMID:7763882;PMID:99144 -1.4.1.4 * salmonella enterica subsp. enterica serovar typhimurium 291000.0 2 PMID:27404;PMID:3139639;PMID:4144743;PMID:9190263 -1.4.1.4 * streptomyces fradiae 200000.0 2 PMID:2561488 -1.4.1.4 * symbiobacterium toebii 263000.0 2 PMID:11265455;PMID:9385147 -1.4.1.4 * synechocystis sp. 208000.0 2 * -1.4.1.4 * thermococcus kodakarensis 284000.0 2 PMID:9704028 -1.4.1.4 * thermococcus litoralis 350000.0 6 PMID:11139075;PMID:11265468;PMID:15870451;PMID:8135516 -1.4.1.4 * thermococcus profundus 263000.0 2 PMID:8690722 -1.4.1.4 * thermococcus sp. 204000.0 2 PMID:8399386 -1.4.1.4 * thermococcus waiotapuensis 259000.0 2 PMID:12013436 -1.4.1.4 * trichomonas vaginalis 230000.0 1 PMID:2901980 -1.4.1.4 * trypanosoma cruzi 280000.0 2 PMID:27404;PMID:3139639;PMID:4144743;PMID:9190263 -1.4.1.5 * bacillus subtilis 290000.0 1 PMID:4204435 -1.4.1.5 * synechocystis sp. 51400.0 1 PMID:19213808 -1.4.1.8 * kitasatospora aureofaciens 240000.0 2 PMID:7669808 -1.4.1.8 * streptomyces albus 67000.0 3 PMID:10612726;PMID:11386345 -1.4.1.8 * streptomyces coelicolor 70000.0 2 PMID:2324704 -1.4.1.8 * streptomyces fradiae 218000.0 5 PMID:3269392 -1.4.1.8 * streptomyces virginiae 88000.0 2 PMID:2803248 -1.4.1.9 * [bacillus] caldolyticus 325000.0 3 * -1.4.1.9 * bacillus cereus 310000.0 2 * -1.4.1.9 * bacillus licheniformis 360000.0 2 PMID:8597545 -1.4.1.9 * bacillus sp. (in: firmicutes) 280000.0 2 * -1.4.1.9 * citrobacter freundii 320000.0 1 PMID:24475337 -1.4.1.9 * geobacillus stearothermophilus 300000.0 4 PMID:3069133;PMID:7883771 -1.4.1.9 * lysinibacillus sphaericus 340000.0 5 PMID:4331041;PMID:670223 -1.4.1.9 * natrialba magadii 330000.0 2 * -1.4.1.9 * neomoorella thermoacetica 360000.0 3 * -1.4.1.9 * sporosarcina psychrophila 340000.0 2 PMID:8020469 -1.4.1.9 * thermoactinomyces intermedius 340000.0 2 PMID:8020469 -1.4.2.1 * nitrobacter winogradskyi 69000.0 1 PMID:5016640 -1.4.2.3 * pseudomonas sp. 55000.0 2 PMID:22267672 -1.4.3.1 * bos taurus 39000.0 5 PMID:10209293;PMID:2901415;PMID:3611051 -1.4.3.1 * caenorhabditis elegans 42501.0 7 PMID:17140416;PMID:20564561 -1.4.3.1 * homo sapiens 39200.0 2 PMID:31914658;PMID:9163533 -1.4.3.1 * mus musculus 146000.0 2 PMID:17469229;PMID:29292239 -1.4.3.1 * octopus vulgaris 37000.0 1 PMID:7915543 -1.4.3.1 * rattus norvegicus 146000.0 1 PMID:29292239 -1.4.3.1 * sus scrofa 380000.0 5 PMID:17234685;PMID:22684060 -1.4.3.1 * thermomyces dupontii 38300.0 1 PMID:30937498 -1.4.3.1 * vanrija humicola 164000.0 4 PMID:15115779;PMID:8645733 -1.4.3.1 * xenopus laevis 30000.0 1 PMID:10665376 -1.4.3.10 * kocuria rosea 90000.0 5 PMID:22975122;PMID:4341347;PMID:8473854 -1.4.3.10 * rhodococcus erythropolis 108000.0 5 PMID:18183391;PMID:18678871;PMID:32921059 -1.4.3.11 * streptomyces hygroscopicus subsp. hygroscopicus 90000.0 2 PMID:2737205 -1.4.3.11 * streptomyces sp. 140000.0 13 PMID:19531050 -1.4.3.11 * streptomyces violascens 60000.0 1 * -1.4.3.12 * acinetobacter sp. yt-02 91000.0 1 PMID:30524413 -1.4.3.12 * microbacterium oxydans 50000.0 3 PMID:16232609;PMID:23555888;PMID:23793344 -1.4.3.12 * pseudomonas sp. 80000.0 1 PMID:18451 -1.4.3.13 * bos taurus 46000.0 4 PMID:12450117;PMID:12577300;PMID:9524359 -1.4.3.13 * canis lupus familiaris 46000.0 1 PMID:32542505 -1.4.3.13 * danio rerio 50000.0 2 PMID:17283144;PMID:18467084 -1.4.3.13 * gallus gallus 61000.0 4 PMID:33171;PMID:4838158;PMID:7318 -1.4.3.13 * haloterrigena turkmenica 34000.0 1 PMID:30984480 -1.4.3.13 * homo sapiens 130000.0 25 PMID:11284725;PMID:12577300;PMID:12686141;PMID:14550642;PMID:17018530;PMID:17287363;PMID:17354256;PMID:17471532;PMID:17616686;PMID:17685448;PMID:17931358;PMID:18037624;PMID:20600936;PMID:20717923;PMID:31340433 -1.4.3.13 * mammalia 50000.0 2 PMID:9524359 -1.4.3.13 * mus musculus 52000.0 12 PMID:15609098;PMID:17283144;PMID:17287363;PMID:17471532;PMID:17616686;PMID:17685448;PMID:17931358;PMID:18467084;PMID:18560621;PMID:21106372 -1.4.3.13 * ovis aries 30000.0 1 PMID:21106372 -1.4.3.13 * rattus norvegicus 50000.0 5 PMID:12577300;PMID:17981747;PMID:18060869;PMID:9524359 -1.4.3.13 * sus scrofa 32000.0 1 PMID:17981747 -1.4.3.14 * rheinheimera sp. 71000.0 1 PMID:25919624 -1.4.3.14 * trichoderma aureoviride 116000.0 1 PMID:23234070;PMID:23777857 -1.4.3.14 * trichoderma cf. aureoviride 116000.0 1 PMID:23234070;PMID:23777857 -1.4.3.14 * trichoderma pseudokoningii 58000.0 1 * -1.4.3.14 * trichoderma viride 119000.0 4 PMID:6101334 -1.4.3.16 * arabidopsis thaliana 127000.0 2 PMID:29650151 -1.4.3.16 * bacillus subtilis 115000.0 2 PMID:18959769 -1.4.3.16 * escherichia coli 60280.0 2 PMID:2187483;PMID:2841129 -1.4.3.16 * gossypium hirsutum 83000.0 1 PMID:6338879 -1.4.3.16 * pseudomonas putida 60000.0 2 * -1.4.3.16 * pyrococcus horikoshii 151000.0 2 PMID:12215812 -1.4.3.16 * sulfurisphaera tokodaii 536467.0 7 PMID:18226609;PMID:23371294 -1.4.3.16 * thermococcus litoralis 140000.0 1 PMID:29143132 -1.4.3.19 * bacillus subtilis 187600.0 18 PMID:11874460;PMID:16739945;PMID:17894345;PMID:17976850;PMID:20690620;PMID:9827558 -1.4.3.19 * geobacillus kaustophilus 172000.0 4 PMID:17894345;PMID:17976850 -1.4.3.2 * agkistrodon laticinctus 120000.0 4 PMID:10441379;PMID:11907037;PMID:12175601;PMID:17127077;PMID:18346051;PMID:22963728 -1.4.3.2 * agkistrodon piscivorus piscivorus 150000.0 1 * -1.4.3.2 * aplysia californica 60000.0 1 PMID:16155232;PMID:24077723 -1.4.3.2 * aplysia punctata 60167.0 2 PMID:16153453 -1.4.3.2 * aspergillus fumigatus 93000.0 1 * -1.4.3.2 * aspergillus oryzae 110000.0 1 * -1.4.3.2 * bacillus carotarum 115000.0 3 PMID:24077723 -1.4.3.2 * bothrops alternatus 123000.0 3 PMID:15142548;PMID:16809041;PMID:17140417;PMID:19523971;PMID:22963728;PMID:27394649;PMID:29898379;PMID:8080286 -1.4.3.2 * bothrops atrox 67000.0 1 PMID:18804547 -1.4.3.2 * bothrops insularis 68000.0 1 PMID:17983639 -1.4.3.2 * bothrops jararaca 125000.0 5 PMID:10441379;PMID:11907037;PMID:17127077;PMID:18346051;PMID:18555977;PMID:19101583;PMID:22963728 -1.4.3.2 * bothrops jararacussu 54760.0 1 PMID:17292326 -1.4.3.2 * bothrops marajoensis 72000.0 1 PMID:19944711 -1.4.3.2 * bothrops moojeni 140000.0 6 PMID:12175601;PMID:17292326;PMID:17320169 -1.4.3.2 * bothrops pauloensis 65000.0 2 PMID:19135502 -1.4.3.2 * bothrops pictus 132000.0 1 PMID:29024770;PMID:8080286 -1.4.3.2 * bothrops pirajai 130000.0 2 PMID:15142548;PMID:16809041;PMID:8080286 -1.4.3.2 * bungarus fasciatus 70000.0 2 PMID:19393676;PMID:23287728 -1.4.3.2 * calloselasma rhodostoma 132000.0 5 PMID:10441379;PMID:11907037;PMID:12175601;PMID:15142548;PMID:16809041;PMID:17127077;PMID:18346051;PMID:22963728;PMID:29024770;PMID:8080286 -1.4.3.2 * cerastes cerastes 115000.0 2 PMID:25009089 -1.4.3.2 * cerastes vipera 120000.0 1 PMID:15142548;PMID:17140417;PMID:19523971;PMID:22963728;PMID:29898379 -1.4.3.2 * chlamydomonas reinhardtii 1300000.0 4 PMID:8344302 -1.4.3.2 * corynebacterium sp. 140000.0 1 PMID:1115559 -1.4.3.2 * crotalus adamanteus 153000.0 5 PMID:12175601;PMID:13843884;PMID:5817156 -1.4.3.2 * crotalus atrox 140000.0 2 PMID:12175601 -1.4.3.2 * crotalus durissus cumanensis 56827.0 2 PMID:19393676;PMID:23287728 -1.4.3.2 * crotalus durissus terrificus 113000.0 2 PMID:11907037;PMID:16307769;PMID:27317870 -1.4.3.2 * daboia russelii 63600.0 3 PMID:21802487 -1.4.3.2 * daboia siamensis 120000.0 2 PMID:15142548;PMID:17140417;PMID:19523971;PMID:22963728;PMID:29898379 -1.4.3.2 * deinagkistrodon acutus 96000.0 1 PMID:18415865 -1.4.3.2 * eristicophis macmahoni 132000.0 3 PMID:11368308;PMID:12175601 -1.4.3.2 * gloydius blomhoffii 60000.0 1 PMID:19279192 -1.4.3.2 * gloydius halys 60700.0 1 PMID:15103157 -1.4.3.2 * gloydius ussuriensis 124400.0 5 PMID:17854853;PMID:20100538 -1.4.3.2 * hebeloma cylindrosporum 216000.0 1 PMID:32852125 -1.4.3.2 * lachesis muta 120000.0 4 PMID:10441379;PMID:11907037;PMID:15142548;PMID:17127077;PMID:17140417;PMID:18346051;PMID:19523971;PMID:22963728;PMID:29898379 -1.4.3.2 * macrovipera lebetinus 140000.0 3 PMID:16828829 -1.4.3.2 * mus musculus 113000.0 4 PMID:10441379;PMID:11907037;PMID:17127077;PMID:18346051;PMID:19276171;PMID:22963728;PMID:27317870 -1.4.3.2 * myoxocephalus polyacanthocephalus 600000.0 7 PMID:19447190 -1.4.3.2 * naja kaouthia 112000.0 2 PMID:12175601 -1.4.3.2 * naja oxiana 110000.0 2 PMID:12503878;PMID:18294891;PMID:22704811;PMID:24077723 -1.4.3.2 * neurospora crassa 300000.0 1 PMID:5052831 -1.4.3.2 * ophiophagus hannah 150000.0 8 PMID:12175601;PMID:17543361;PMID:2619759;PMID:3188059;PMID:7886693;PMID:9304806 -1.4.3.2 * penicillium steckii 290000.0 1 PMID:24333187 -1.4.3.2 * platichthys stellatus 52000.0 1 PMID:20015076 -1.4.3.2 * proteus mirabilis 57151.0 2 PMID:21298676;PMID:7592338 -1.4.3.2 * protobothrops jerdonii 110000.0 2 PMID:12503878;PMID:18294891;PMID:22704811;PMID:24077723 -1.4.3.2 * protobothrops mucrosquamatus 140000.0 3 PMID:12175601;PMID:2619759;PMID:3188059 -1.4.3.2 * pseudechis australis 142000.0 2 PMID:12175601 -1.4.3.2 * pseudoalteromonas luteoviolacea 110000.0 2 PMID:12503878;PMID:18294891;PMID:18504575;PMID:22704811;PMID:24077723 -1.4.3.2 * pseudoalteromonas maricaloris 60000.0 2 PMID:16155232;PMID:19279192;PMID:24077723 -1.4.3.2 * pseudomonas sp. 110000.0 2 PMID:12503878;PMID:18294891;PMID:22704811;PMID:24077723 -1.4.3.2 * rattus norvegicus 314000.0 2 PMID:5684620 -1.4.3.2 * rhodococcus opacus 542000.0 5 PMID:16511322 -1.4.3.2 * rhodococcus sp. (in: high g+c gram-positive bacteria) 102000.0 1 PMID:24077723 -1.4.3.2 * rhodococcus sp. aiu lab-3 105000.0 1 PMID:24077723 -1.4.3.2 * sebastes schlegelii 160000.0 8 PMID:15142548;PMID:17140417;PMID:17964810;PMID:19523971;PMID:20728563;PMID:22963728;PMID:29898379 -1.4.3.2 * streptococcus cristatus 43000.0 1 PMID:18469105 -1.4.3.2 * synechococcus elongatus pcc 6301 54130.0 1 PMID:17542496 -1.4.3.2 * synechococcus elongatus pcc 7942 = fachb-805 98000.0 2 PMID:6766743 -1.4.3.2 * trichoderma harzianum 63500.0 1 PMID:24077723 -1.4.3.2 * vipera ammodytes ammodytes 55000.0 1 PMID:18931435 -1.4.3.20 * marinomonas mediterranea 200000.0 6 PMID:15652194;PMID:20025674;PMID:20599635;PMID:23908359;PMID:25896319 -1.4.3.21 * aspergillus carbonarius 130000.0 2 PMID:25468423 -1.4.3.21 * aspergillus nidulans 30000.0 1 PMID:21604787 -1.4.3.21 * euphorbia characias 200000.0 2 PMID:23839010;PMID:25084330 -1.4.3.21 * huperzia serrata 162000.0 3 PMID:22901898 -1.4.3.21 * lens culinaris 200000.0 1 PMID:25084330 -1.4.3.21 * mycobacterium sp. 300000.0 4 PMID:18400766 -1.4.3.21 * ogataea angusta 72000.0 1 PMID:20155950 -1.4.3.21 * rattus norvegicus 184000.0 2 PMID:17385065 -1.4.3.21 * rhodococcus opacus 140000.0 4 * -1.4.3.21 * sus scrofa 1200000.0 7 PMID:218560;PMID:2848544;PMID:6615797 -1.4.3.22 * aspergillus niger 150000.0 3 PMID:2798365;PMID:8620882 -1.4.3.22 * crystallibacter crystallopoietes 81000.0 1 PMID:16233600 -1.4.3.22 * euphorbia characias 140000.0 2 PMID:6814913 -1.4.3.22 * glycine max 145000.0 4 PMID:8239662 -1.4.3.22 * homo sapiens 235000.0 6 PMID:182134;PMID:23371442;PMID:27063138;PMID:808238 -1.4.3.22 * hyoscyamus niger 135000.0 2 PMID:16667438 -1.4.3.22 * lathyrus cicera 150000.0 2 PMID:2798365;PMID:8620882 -1.4.3.22 * lathyrus odoratus 140000.0 2 PMID:6814913 -1.4.3.22 * lathyrus oleraceus 180000.0 2 * -1.4.3.22 * lathyrus sativus 148000.0 2 PMID:21644017;PMID:6814913 -1.4.3.22 * lens culinaris 187000.0 2 * -1.4.3.22 * natrinema gari 87600.0 4 PMID:25005094 -1.4.3.22 * nicotiana tabacum 106000.0 1 PMID:17174363 -1.4.3.22 * onobrychis viciifolia 145000.0 2 * -1.4.3.22 * oryza sativa 123000.0 2 * -1.4.3.22 * papaver somniferum 83000.0 1 * -1.4.3.22 * phaseolus vulgaris 150000.0 2 PMID:2798365;PMID:8620882 -1.4.3.22 * rattus norvegicus 80000.0 1 * -1.4.3.22 * seriola quinqueradiata 140000.0 3 PMID:6814913 -1.4.3.22 * trifolium subterraneum 150000.0 2 PMID:2798365;PMID:8620882 -1.4.3.22 * triticum aestivum 110000.0 2 * -1.4.3.22 * vicia faba 126000.0 4 PMID:22228559 -1.4.3.23 * lentzea aerocolonigenes 110000.0 3 PMID:15743957;PMID:16313168 -1.4.3.25 * pseudomonas sp. 528000.0 3 PMID:26672462 -1.4.3.25 * synechococcus elongatus pcc 7942 = fachb-805 98000.0 2 PMID:6766743 -1.4.3.25 * synechococcus sp. 50000.0 1 PMID:8652660 -1.4.3.3 * [candida] boidinii 43000.0 2 PMID:11330678 -1.4.3.3 * caenorhabditis elegans 36117.0 1 PMID:20564561 -1.4.3.3 * candida tropicalis 39000.0 1 * -1.4.3.3 * cyprinus carpio 39000.0 1 PMID:14622982;PMID:16332786;PMID:23247086;PMID:23994361;PMID:2865242 -1.4.3.3 * glutamicibacter protophormiae 69000.0 2 PMID:17279391 -1.4.3.3 * homo sapiens 80000.0 5 PMID:18220846;PMID:18343336;PMID:18544534;PMID:19309736 -1.4.3.3 * neurospora crassa 125000.0 1 PMID:13919 -1.4.3.3 * rasamsonia emersonii 185000.0 1 PMID:31420577 -1.4.3.3 * rattus norvegicus 40000.0 1 PMID:21981077 -1.4.3.3 * rhodotorula toruloides 80150.0 14 PMID:12208501;PMID:15701048;PMID:17145127;PMID:17396222;PMID:18220846;PMID:18330517;PMID:18343336;PMID:18544534;PMID:2565232 -1.4.3.3 * rubrobacter xylanophilus 24100.0 1 PMID:25217016 -1.4.3.3 * schizosaccharomyces pombe 39000.0 2 PMID:23085840 -1.4.3.3 * sus scrofa 115000.0 9 PMID:15701048;PMID:17990314;PMID:18220846;PMID:18343336;PMID:18544534 -1.4.3.3 * trigonopsis variabilis 570000.0 14 PMID:11130179;PMID:14622982;PMID:15701048;PMID:16332786;PMID:16538681;PMID:17145127;PMID:18330517;PMID:18696261;PMID:23157298;PMID:23247086;PMID:23994361;PMID:2865242;PMID:7905327 -1.4.3.3 * xenopus laevis 39000.0 1 PMID:14622982;PMID:16332786;PMID:23247086;PMID:23994361;PMID:2865242 -1.4.3.3 * zea mays 78000.0 1 PMID:19267668 -1.4.3.4 * aspergillus niger 215000.0 2 PMID:7727530 -1.4.3.4 * avena sativa 220000.0 5 * -1.4.3.4 * bos taurus 146000.0 3 PMID:434814;PMID:708061 -1.4.3.4 * cyprinus carpio 59001.0 1 PMID:19932189 -1.4.3.4 * danio rerio 60000.0 2 PMID:20079438 -1.4.3.4 * homo sapiens 65000.0 7 PMID:11049757;PMID:11812236;PMID:15501256;PMID:4729296;PMID:708051 -1.4.3.4 * narcissus tazetta 135000.0 3 PMID:23924738 -1.4.3.4 * rattus norvegicus 65000.0 6 PMID:15501256;PMID:18424170;PMID:19883764;PMID:708051;PMID:7081997 -1.4.3.4 * sus scrofa 120000.0 4 PMID:3096981;PMID:5165518;PMID:5657868 -1.4.3.5 * arabidopsis thaliana 49000.0 1 PMID:21051239 -1.4.3.5 * bacillus subtilis 31480.0 1 PMID:19074821 -1.4.3.5 * bombyx mori 60000.0 2 PMID:19523068 -1.4.3.5 * escherichia coli 51000.0 3 PMID:7696318;PMID:7860596;PMID:9693059 -1.4.3.5 * mycobacterium tuberculosis 55380.0 4 PMID:16880544;PMID:22110704;PMID:235547;PMID:440132 -1.4.3.5 * oryctolagus cuniculus 55000.0 3 PMID:22110704;PMID:235547;PMID:440132;PMID:475395 -1.4.3.5 * saccharomyces cerevisiae 55000.0 4 PMID:7896706 -1.4.3.5 * schistosoma mansoni 28878.0 1 PMID:33613557 -1.4.3.5 * sus scrofa 60000.0 2 PMID:6697989 -1.4.3.7 * [candida] boidinii 45000.0 2 PMID:4387700 -1.4.4.2 * arthrobacter globiformis 270000.0 1 PMID:4414614 -1.4.4.2 * c3-plants 97000.0 1 PMID:8206222 -1.4.4.2 * escherichia coli 200000.0 1 PMID:18941301 -1.4.4.2 * gallus gallus 208000.0 3 PMID:18941301;PMID:7440562 -1.4.4.2 * gottschalkia acidurici 200000.0 1 PMID:18941301 -1.4.4.2 * homo sapiens 200000.0 1 PMID:18941301 -1.4.4.2 * lathyrus oleraceus 210000.0 5 PMID:18941301;PMID:3080433;PMID:3143355;PMID:8595976 -1.4.4.2 * peptoclostridium acidaminophilum 225000.0 4 PMID:18941301;PMID:2495273 -1.4.4.2 * rattus norvegicus 210000.0 3 PMID:6778858 -1.4.4.2 * saccharomyces cerevisiae 114400.0 1 PMID:8830251 -1.4.4.2 * synechocystis sp. 215000.0 1 PMID:20124719 -1.4.4.2 * thermus thermophilus 200000.0 1 PMID:18941301 -1.4.4.2 * trichomonas vaginalis 52000.0 6 PMID:17158739 -1.4.4.2 * zea mays 220000.0 5 PMID:17945380 -1.4.5.1 * escherichia coli b 55000.0 2 PMID:6102989 -1.4.5.1 * helicobacter pylori 46040.0 2 PMID:19212808 -1.4.5.1 * pseudomonas aeruginosa 49000.0 1 PMID:3101751 -1.4.7.1 * arabidopsis thaliana 165000.0 2 PMID:19555410 -1.4.7.1 * chlamydomonas reinhardtii 165000.0 4 PMID:17237175;PMID:24254054 -1.4.7.1 * glycine max 165000.0 1 * -1.4.7.1 * haloferax mediterranei 198000.0 2 PMID:24292444 -1.4.7.1 * hydrogenobacter thermophilus 168000.0 4 PMID:17237175;PMID:24254054 -1.4.7.1 * leptolyngbya boryana 16000.0 1 PMID:22442234 -1.4.7.1 * medicago sativa 68200.0 1 PMID:3190691 -1.4.7.1 * oryza sativa 224000.0 2 PMID:16662307 -1.4.7.1 * pinus pinaster 168000.0 2 PMID:7865781 -1.4.7.1 * solanum lycopersicum 153000.0 3 PMID:16665799 -1.4.7.1 * spinacia oleracea 180000.0 4 PMID:6746604 -1.4.7.1 * synechocystis sp. 178000.0 2 PMID:10898944 -1.4.7.1 * zea mays 171000.0 3 PMID:16664732 -1.4.9.1 * hyphomicrobium zavarzinii 42000.0 2 PMID:18835606 -1.4.9.1 * methylorubrum extorquens 41170.0 6 PMID:9748238 -1.4.9.1 * mycobacterium convolutum 38500.0 1 PMID:1176433 -1.4.9.1 * paracoccus denitrificans 119000.0 7 PMID:10346915;PMID:19270386;PMID:20223990 -1.4.9.1 * paracoccus versutus 138000.0 3 PMID:18512962 -1.4.9.1 * pseudomonas putida 112000.0 12 PMID:11555656;PMID:18177365;PMID:26667 -1.4.9.1 * pseudomonas sp. 133000.0 6 PMID:10346915;PMID:5124384 -1.4.9.2 * achromobacter xylosoxidans 95500.0 3 PMID:15388968 -1.4.9.2 * alcaligenes faecalis 114000.0 11 PMID:11495996;PMID:17475620;PMID:3037269;PMID:6830237;PMID:8188594 -1.4.9.2 * pseudomonas putida 120000.0 4 * -1.4.9.2 * pseudomonas sp. 103000.0 3 PMID:3037269;PMID:6830237 -1.4.99.6 * helicobacter pylori 46040.0 2 PMID:19212808 -1.4.99.6 * helicobacter pylori nctc 11637 = ccug 17874 = atcc 43504 = jcm 12093 44000.0 1 PMID:19720515 -1.5.1.1 * azospirillum brasilense 78000.0 4 PMID:24649405 -1.5.1.1 * colwellia psychrerythraea 81000.0 3 PMID:24649405 -1.5.1.10 * penicillium chrysogenum 48000.0 1 PMID:11717275 -1.5.1.10 * pyricularia grisea 84000.0 3 * -1.5.1.10 * saccharomyces cerevisiae 73000.0 3 PMID:3098733 -1.5.1.11 * cerastoderma edule 37000.0 1 PMID:1001693 -1.5.1.11 * cerebratulus lacteus 41500.0 2 * -1.5.1.11 * concholepas concholepas 52000.0 1 * -1.5.1.11 * helianthus annuus 39000.0 2 PMID:16661312 -1.5.1.11 * metridium senile 40000.0 2 * -1.5.1.11 * mytilus galloprovincialis 70000.0 2 PMID:21791249 -1.5.1.11 * pecten maximus 46000.0 6 PMID:18028427;PMID:4341739;PMID:6997038 -1.5.1.15 * acetobacterium woodii 69000.0 5 PMID:6608524 -1.5.1.15 * clostridium formicaceticum 60000.0 2 PMID:4153026 -1.5.1.15 * homo sapiens 37000.0 4 PMID:29225823;PMID:3258307;PMID:8424951;PMID:9250981 -1.5.1.15 * methanosarcina barkeri 318700.0 2 PMID:15349715 -1.5.1.15 * mus musculus 68000.0 4 PMID:2647744;PMID:3074630;PMID:3261979;PMID:3487546 -1.5.1.15 * saccharomyces cerevisiae 64000.0 4 PMID:2223762;PMID:8990502;PMID:9250982 -1.5.1.16 * nicotiana tabacum 39000.0 1 * -1.5.1.17 * aphrodita aculeata 44000.0 1 * -1.5.1.17 * concholepas concholepas 42000.0 1 * -1.5.1.17 * conomurex luhuanus 42000.0 1 * -1.5.1.17 * littorina littorea 42400.0 2 * -1.5.1.17 * magallana gigas 47200.0 2 PMID:7238503 -1.5.1.17 * mytilus edulis 38500.0 1 * -1.5.1.19 * helianthus annuus 158000.0 2 PMID:476084 -1.5.1.2 * acetoanaerobium sticklandii 230000.0 2 * -1.5.1.2 * anabaena sp. 28140.0 1 PMID:24431521 -1.5.1.2 * arabidopsis thaliana 354000.0 2 PMID:24467670 -1.5.1.2 * cucurbita moschata 100000.0 1 * -1.5.1.2 * escherichia coli 320000.0 5 PMID:12005058;PMID:12133;PMID:19027071;PMID:6296787 -1.5.1.2 * glycine max 30000.0 1 PMID:3753884 -1.5.1.2 * homo sapiens 370000.0 1 PMID:16600630 -1.5.1.2 * hordeum vulgare 30000.0 1 PMID:16664571 -1.5.1.2 * mycobacterium tuberculosis 365000.0 2 PMID:16199181 -1.5.1.2 * neisseria meningitidis 58800.0 1 PMID:16233902 -1.5.1.2 * pseudomonas aeruginosa 94000.0 1 PMID:114173 -1.5.1.2 * rattus norvegicus 240000.0 2 PMID:3753884 -1.5.1.2 * saccharolobus solfataricus 320000.0 2 PMID:12133;PMID:19027071 -1.5.1.2 * saccharomyces cerevisiae 125000.0 1 PMID:7004492 -1.5.1.2 * spinacia oleracea 310000.0 2 PMID:11479381 -1.5.1.2 * streptococcus pyogenes 284600.0 1 PMID:16233902 -1.5.1.20 * arabidopsis sp. 141000.0 2 PMID:10593891 -1.5.1.20 * clostridium formicaceticum 237000.0 7 PMID:3517570;PMID:6381490 -1.5.1.20 * clostridium ljungdahlii 106000.0 1 PMID:34255221 -1.5.1.20 * escherichia coli 190000.0 4 PMID:10201405;PMID:10593891;PMID:11742092;PMID:12667083 -1.5.1.20 * homo sapiens 150000.0 3 PMID:2383427 -1.5.1.20 * leishmania major 34800.0 1 PMID:17032644 -1.5.1.20 * schizosaccharomyces pombe 69000.0 1 PMID:12112238 -1.5.1.20 * sus scrofa 190000.0 4 PMID:1186901;PMID:3702701 -1.5.1.20 * zea mays 66400.0 1 PMID:10593891 -1.5.1.21 * bos taurus 50000.0 1 PMID:24043460 -1.5.1.21 * pseudomonas aeruginosa 78000.0 1 PMID:24649405 -1.5.1.21 * pseudomonas putida 200000.0 1 PMID:6801013 -1.5.1.21 * pseudomonas syringae 36000.0 1 PMID:16192274 -1.5.1.21 * sus scrofa 70000.0 1 PMID:24043460 -1.5.1.22 * aphrodita aculeata 44000.0 1 * -1.5.1.22 * marphysa sanguinea 43350.0 3 * -1.5.1.22 * meretrix lusoria 46000.0 1 PMID:20851773 -1.5.1.22 * mytilus edulis 38200.0 1 * -1.5.1.22 * suberites domuncula 75000.0 4 PMID:19454319 -1.5.1.23 * arabella iricolor 43700.0 5 PMID:15694596;PMID:8840516 -1.5.1.23 * halichondria japonica 37000.0 3 * -1.5.1.23 * haliotis discus hannai 42000.0 1 * -1.5.1.23 * haliotis tuberculata lamellosa 42000.0 2 PMID:3769931 -1.5.1.23 * mazzaella japonica 39000.0 1 * -1.5.1.23 * patiria pectinifera 42400.0 2 PMID:10075484 -1.5.1.23 * suberites domuncula 36920.0 2 * -1.5.1.24 * clostridium botulinum 125000.0 3 PMID:19933367 -1.5.1.24 * lactococcus lactis 150000.0 23 PMID:10525296;PMID:10548058;PMID:2163399;PMID:24190788;PMID:2498334;PMID:7744873 -1.5.1.25 * bos taurus 100000.0 2 PMID:3191146 -1.5.1.25 * sus scrofa 76000.0 2 PMID:3371353 -1.5.1.26 * cellana grata 40800.0 2 * -1.5.1.27 * papaver somniferum 30000.0 1 * -1.5.1.28 * arthrobacter sp. 70000.0 3 PMID:2753861;PMID:7487048 -1.5.1.3 * babesia gibsoni 57000.0 1 PMID:18794380 -1.5.1.3 * bacteria 35000.0 1 * -1.5.1.3 * bombyx mori 25000.0 2 PMID:23065260 -1.5.1.3 * bos taurus 23000.0 5 PMID:1204646;PMID:1252081;PMID:45 -1.5.1.3 * burkholderia cepacia 24000.0 1 PMID:2802552 -1.5.1.3 * candida albicans 25000.0 1 PMID:2642898 -1.5.1.3 * cricetulus griseus 24000.0 2 PMID:15711;PMID:9056490 -1.5.1.3 * cricetulus sp. 26000.0 1 PMID:5062896 -1.5.1.3 * crithidia fasciculata 110000.0 6 PMID:6934511 -1.5.1.3 * daucus carota 45000.0 1 PMID:16453780 -1.5.1.3 * drosophila melanogaster 17000.0 1 PMID:2116172 -1.5.1.3 * enterococcus faecium 28000.0 3 PMID:5021603;PMID:5687716 -1.5.1.3 * escherichia coli 36000.0 9 PMID:19054;PMID:22171795;PMID:29799386;PMID:3109322;PMID:33983;PMID:376528;PMID:4405201;PMID:46;PMID:6838817;PMID:7275974;PMID:9989225 -1.5.1.3 * gallus gallus 23000.0 2 PMID:4379915;PMID:6766736 -1.5.1.3 * geobacillus stearothermophilus 20000.0 3 PMID:16114879 -1.5.1.3 * glycine max 140000.0 2 PMID:29799386;PMID:3109322;PMID:6838817;PMID:7275974;PMID:820266 -1.5.1.3 * halalkalibacterium halodurans 20157.0 2 PMID:17021659 -1.5.1.3 * heliothis virescens 21000.0 1 PMID:10632709 -1.5.1.3 * homo sapiens 42000.0 7 PMID:12949104;PMID:15019741;PMID:18067453;PMID:20393885;PMID:29799386;PMID:3109322;PMID:4396284;PMID:6838817;PMID:7275974 -1.5.1.3 * lacticaseibacillus casei 18300.0 3 PMID:10886;PMID:4401226 -1.5.1.3 * lactobacillus leichmannii 20000.0 1 PMID:10983423 -1.5.1.3 * leishmania tropica 110000.0 2 PMID:3922404 -1.5.1.3 * moritella profunda 19000.0 2 PMID:12949104;PMID:15019741 -1.5.1.3 * mus musculus 21460.0 3 PMID:19040;PMID:4401610 -1.5.1.3 * mycobacterium tuberculosis 19000.0 2 PMID:12949104;PMID:15019741 -1.5.1.3 * mycolicibacterium phlei 15000.0 1 PMID:3741386 -1.5.1.3 * neisseria gonorrhoeae 173000.0 3 PMID:6434541 -1.5.1.3 * plasmodium knowlesi 147000.0 1 PMID:30114522 -1.5.1.3 * pneumocystis carinii 25000.0 2 PMID:11036028;PMID:8425104 -1.5.1.3 * rattus norvegicus 22500.0 2 PMID:7165835 -1.5.1.3 * saccharomyces cerevisiae 39000.0 1 PMID:4403556 -1.5.1.3 * salmonella enterica subsp. enterica serovar typhimurium 16900.0 2 PMID:6371010 -1.5.1.3 * streptococcus pneumoniae 20000.0 1 PMID:4392233 -1.5.1.3 * sus scrofa 22500.0 2 PMID:500653 -1.5.1.3 * tequatrovirus t4 29000.0 1 PMID:4405201 -1.5.1.3 * tetradesmus obliquus 100000.0 2 PMID:3606123 -1.5.1.3 * thermotoga maritima 36000.0 4 PMID:12765545;PMID:9738902 -1.5.1.30 * aliivibrio fischeri 49200.0 2 PMID:18264585 -1.5.1.30 * bacillus subtilis 76000.0 5 PMID:16752898;PMID:19147107;PMID:9836433 -1.5.1.30 * entamoeba histolytica 40000.0 1 PMID:6258069 -1.5.1.30 * escherichia coli 26000.0 1 PMID:19139094 -1.5.1.30 * homo sapiens 22000.0 3 PMID:3453680;PMID:34598 -1.5.1.30 * rhodococcus erythropolis 86000.0 2 PMID:11229908 -1.5.1.30 * shigella flexneri 113600.0 2 PMID:17962405 -1.5.1.30 * streptococcus pneumoniae 45000.0 1 PMID:29321514 -1.5.1.30 * streptomyces viridifaciens 36000.0 3 PMID:9287340 -1.5.1.30 * vibrio harveyi 53783.0 9 PMID:12733657;PMID:18067321;PMID:18264585;PMID:18294448;PMID:8206832;PMID:8990272 -1.5.1.32 * rauvolfia serpentina 43000.0 3 PMID:11937349 -1.5.1.33 * agrobacterium fabrum 60000.0 1 PMID:32482721 -1.5.1.33 * leishmania donovani 134000.0 4 PMID:15555938;PMID:17275814 -1.5.1.33 * leishmania major 117000.0 5 PMID:15388924;PMID:9153248 -1.5.1.33 * leishmania sp. 51000.0 1 PMID:21079660 -1.5.1.33 * leishmania tarentolae 116800.0 3 PMID:9153248;PMID:9186479 -1.5.1.33 * trypanosoma cruzi 30000.0 1 PMID:9476799 -1.5.1.34 * badhamia polycephala 46000.0 2 PMID:12956422 -1.5.1.34 * bos taurus 70000.0 9 PMID:16875;PMID:191436;PMID:3037253;PMID:3600365;PMID:3711039 -1.5.1.34 * crithidia fasciculata 55000.0 1 PMID:7370274 -1.5.1.34 * dictyostelium discoideum 50000.0 3 PMID:18997329 -1.5.1.34 * drosophila melanogaster 24528.0 1 PMID:11004497 -1.5.1.34 * escherichia coli 54000.0 3 PMID:3060113 -1.5.1.34 * homo sapiens 69000.0 7 PMID:3033643;PMID:3600366;PMID:3711039;PMID:7317032 -1.5.1.34 * ovis aries 47000.0 4 PMID:3600367;PMID:3600388;PMID:4405600 -1.5.1.34 * pseudomonas sp. 49000.0 1 PMID:8429 -1.5.1.34 * rattus norvegicus 51000.0 6 PMID:3680258;PMID:3729422;PMID:7174633 -1.5.1.34 * rhodobacter capsulatus 25000.0 1 PMID:18355323 -1.5.1.34 * thermus thermophilus 23000.0 1 PMID:14702303 -1.5.1.36 * [clostridium] scindens 210000.0 2 PMID:7599167;PMID:8491719 -1.5.1.36 * escherichia coli 20000.0 2 PMID:10633095 -1.5.1.36 * escherichia coli w 20000.0 3 PMID:10633095;PMID:8077235 -1.5.1.36 * mycolicibacterium goodii 39000.0 3 * -1.5.1.36 * pseudomonas aeruginosa 19400.0 1 PMID:20000468 -1.5.1.36 * pseudomonas putida 18000.0 1 PMID:19420991 -1.5.1.37 * paraburkholderia phenoliruptrix 22000.0 1 PMID:12700257 -1.5.1.37 * pseudomonas aeruginosa 19400.0 1 PMID:20000468 -1.5.1.37 * pseudomonas protegens pf-5 39000.0 2 PMID:17921302 -1.5.1.37 * pseudomonas putida 37000.0 1 PMID:23524667 -1.5.1.38 * bacillus cereus 60000.0 1 PMID:26415543 -1.5.1.38 * escherichia coli 73100.0 6 PMID:10480865;PMID:24816272;PMID:29979040 -1.5.1.38 * plasmodium falciparum 60480.0 1 PMID:31381947 -1.5.1.38 * plasmodium vivax 59960.0 1 PMID:31381947 -1.5.1.38 * vibrio harveyi 63000.0 4 PMID:1175652;PMID:8206832;PMID:880288 -1.5.1.39 * lacticaseibacillus rhamnosus 42000.0 1 PMID:32044036 -1.5.1.40 * archaeoglobus fulgidus 57000.0 3 PMID:2492438 -1.5.1.40 * methanococcus vannielii 85000.0 2 PMID:7391030 -1.5.1.40 * methanogenium organophilum 90000.0 2 PMID:9325428 -1.5.1.40 * methanosphaera stadtmanae 148000.0 4 PMID:11109487 -1.5.1.40 * methanothermobacter thermautotrophicus 110000.0 3 PMID:9821972 -1.5.1.40 * streptomyces griseus 42000.0 2 PMID:2492438 -1.5.1.41 * escherichia coli 28000.0 2 PMID:2050627;PMID:3305505 -1.5.1.42 * pseudomonas putida 37200.0 1 PMID:23524667 -1.5.1.42 * rhodococcus erythropolis 22000.0 1 PMID:20349330 -1.5.1.42 * vibrio harveyi 31000.0 5 PMID:1175652;PMID:47604;PMID:8167139;PMID:880288 -1.5.1.43 * vibrio alginolyticus 93500.0 2 PMID:1955861 -1.5.1.44 * aspergillus fumigatus 33300.0 3 PMID:20526482 -1.5.1.44 * penicillium camemberti 122900.0 1 PMID:28902217 -1.5.1.44 * penicillium commune 32600.0 2 PMID:20526482 -1.5.1.46 * claviceps purpurea 33300.0 5 PMID:21494745 -1.5.1.47 * methylorubrum extorquens 38500.0 2 PMID:15028691 -1.5.1.48 * streptomyces sp. 65000.0 2 PMID:21897027 -1.5.1.5 * clostridium cylindrosporum 70000.0 1 PMID:4383631 -1.5.1.5 * escherichia coli 22000.0 1 PMID:29799386 -1.5.1.5 * homo sapiens 101000.0 4 PMID:18804703;PMID:29225823;PMID:3053686 -1.5.1.5 * hyphomicrobium zavarzinii 31000.0 1 PMID:11889483;PMID:8765228 -1.5.1.5 * lathyrus oleraceus 60000.0 4 PMID:8304211 -1.5.1.5 * leishmania major 65000.0 2 PMID:22108435 -1.5.1.5 * neomoorella thermoacetica 55000.0 3 PMID:4405422;PMID:6966369 -1.5.1.5 * ovis aries 228000.0 5 PMID:6990198;PMID:956178 -1.5.1.5 * photobacterium phosphoreum 31000.0 1 PMID:11889483;PMID:8765228 -1.5.1.5 * saccharomyces cerevisiae 201000.0 3 PMID:329838;PMID:6990198 -1.5.1.5 * sus scrofa 150000.0 3 PMID:4147884;PMID:6966370;PMID:6990198;PMID:838698 -1.5.1.5 * thermoplasma acidophilum 30600.0 1 PMID:18309272 -1.5.1.51 * staphylococcus aureus 81000.0 3 PMID:24485762 -1.5.1.53 * sus scrofa 210000.0 3 PMID:6975779 -1.5.1.54 * acetobacterium woodii 130000.0 1 PMID:25733614 -1.5.1.54 * blautia producta 250000.0 1 PMID:2209595 -1.5.1.54 * escherichia coli 119000.0 2 PMID:9922232 -1.5.1.54 * mycolicibacterium smegmatis 41000.0 2 PMID:32253341 -1.5.1.6 * danio rerio 400000.0 2 PMID:20381623 -1.5.1.6 * homo sapiens 130000.0 6 PMID:10204077;PMID:20498374;PMID:21238436;PMID:2733692 -1.5.1.6 * mus musculus 96000.0 1 PMID:7972060 -1.5.1.6 * oryctolagus cuniculus 440000.0 2 PMID:7929148;PMID:9758763 -1.5.1.6 * rattus norvegicus 450000.0 14 PMID:17669278;PMID:17697402;PMID:2733692;PMID:3196754;PMID:3392008;PMID:36073;PMID:7646059;PMID:7822273;PMID:7840609;PMID:7929148;PMID:9758763;PMID:9765265 -1.5.1.6 * sus scrofa 320000.0 3 PMID:3196754;PMID:3697368 -1.5.1.7 * candida maltosa 45000.0 1 * -1.5.1.7 * meyerozyma guilliermondii 45000.0 1 PMID:2515798 -1.5.1.7 * saccharomyces cerevisiae 49000.0 4 PMID:21798231;PMID:418069;PMID:4287986 -1.5.1.8 * arabidopsis thaliana 117000.0 1 PMID:9286108;PMID:9426595 -1.5.1.8 * bos taurus 468000.0 3 PMID:3110158;PMID:6434529 -1.5.1.8 * glycine max 256000.0 2 PMID:10859195 -1.5.1.8 * homo sapiens 480000.0 1 PMID:1169916 -1.5.1.8 * oryza sativa 203000.0 2 PMID:9249048 -1.5.1.8 * papio sp. 467000.0 2 PMID:3110158;PMID:6434529 -1.5.1.8 * phaseolus vulgaris 190000.0 1 PMID:12624751 -1.5.1.8 * rattus norvegicus 230000.0 2 PMID:687635 -1.5.1.8 * zea mays 260000.0 2 PMID:9654071 -1.5.1.9 * arabidopsis thaliana 120000.0 2 PMID:11080311 -1.5.1.9 * bos taurus 468000.0 3 PMID:3110158;PMID:6434529 -1.5.1.9 * haemaphysalis longicornis 48000.0 1 PMID:19774086 -1.5.1.9 * homo sapiens 480000.0 1 PMID:242268 -1.5.1.9 * nostoc punctiforme 44100.0 2 PMID:22449979 -1.5.1.9 * oryza sativa 396000.0 3 PMID:9249048 -1.5.1.9 * papio hamadryas 467000.0 2 PMID:3110158;PMID:6434529 -1.5.1.9 * phaseolus vulgaris 190000.0 1 PMID:12624751 -1.5.1.9 * ruegeria pomeroyi 44100.0 2 PMID:22449979 -1.5.1.9 * zea mays 260000.0 2 PMID:12226216 -1.5.3.1 * achromobacter denitrificans 190000.0 1 * -1.5.3.1 * bacillus sp. (in: firmicutes) 51000.0 5 PMID:16977470;PMID:18693755;PMID:20518346;PMID:3594681 -1.5.3.1 * bacillus sp. bsd-8 51700.0 3 PMID:24657588 -1.5.3.1 * corynebacterium sp. 174000.0 10 PMID:3790506;PMID:7240129 -1.5.3.1 * corynebacterium sp. u-96 174000.0 2 PMID:4027239;PMID:6158947 -1.5.3.1 * cylindrocarpon didymum 48000.0 2 * -1.5.3.1 * paenarthrobacter ureafaciens 185000.0 5 * -1.5.3.1 * streptomyces sp. 44000.0 1 PMID:3435943 -1.5.3.1 * thermococcus kodakarensis 160000.0 3 PMID:22083128 -1.5.3.10 * arthrobacter globiformis 88000.0 1 PMID:11422368 -1.5.3.10 * cylindrocarpon didymum 170000.0 2 * -1.5.3.12 * eschscholzia californica 56000.0 1 PMID:24241413 -1.5.3.12 * sanguinaria canadensis 77000.0 1 PMID:9367526 -1.5.3.13 * homo sapiens 55000.0 1 PMID:12477380 -1.5.3.13 * mus musculus 56101.0 1 PMID:12660232 -1.5.3.14 * oryza sativa 64000.0 1 PMID:24634478 -1.5.3.15 * acanthamoeba culbertsoni 64000.0 1 PMID:1565141 -1.5.3.16 * arabidopsis thaliana 55000.0 2 PMID:18703589 -1.5.3.16 * ascaris suum 66000.0 1 PMID:1567380 -1.5.3.16 * homo sapiens 68000.0 5 PMID:11454677;PMID:12727196;PMID:18422650;PMID:20012116 -1.5.3.16 * mus musculus 68000.0 3 PMID:12458219;PMID:15313165 -1.5.3.17 * arabidopsis thaliana 54100.0 2 PMID:18583528 -1.5.3.17 * ascaris suum 66000.0 1 PMID:1567380 -1.5.3.18 * schizosaccharomyces pombe 56000.0 2 PMID:16233628 -1.5.3.18 * slafractonia leguminicola 52000.0 2 PMID:2394693 -1.5.3.19 * paenarthrobacter nicotinovorans 90000.0 2 PMID:15606755 -1.5.3.20 * cladosporium sp. 50000.0 1 PMID:9989229 -1.5.3.21 * paenarthrobacter nicotinovorans 46100.0 2 PMID:16689938 -1.5.3.22 * methanobrevibacter arboriphilus 46100.0 2 PMID:15340796 -1.5.3.22 * methanothermobacter marburgensis 45300.0 2 PMID:15340796 -1.5.3.24 * corynebacterium sp. p-1 168000.0 1 PMID:3790506 -1.5.3.24 * corynebacterium sp. u-96 174000.0 1 PMID:6630175;PMID:7240129 -1.5.3.24 * stenotrophomonas maltophilia 180000.0 1 PMID:16820168 -1.5.3.25 * agrobacterium tumefaciens 85000.0 1 PMID:12506967 -1.5.3.25 * arthrobacter sp. 2-4-1 88000.0 1 * -1.5.3.25 * aspergillus oryzae 98000.0 2 PMID:15466528 -1.5.3.25 * aspergillus sp. 55000.0 2 PMID:9013588 -1.5.3.4 * rattus norvegicus 200000.0 1 PMID:4441079 -1.5.3.5 * paenarthrobacter nicotinovorans 140000.0 5 PMID:4019415;PMID:4405081;PMID:5646150;PMID:9878353;PMID:9929386 -1.5.3.6 * paenarthrobacter nicotinovorans 56000.0 6 PMID:1356985;PMID:3007941;PMID:3905431;PMID:4628374;PMID:6618442;PMID:8810280;PMID:9878353 -1.5.3.7 * macaca mulatta 46000.0 1 * -1.5.3.7 * rhodotorula glutinis 43000.0 1 PMID:6809728 -1.5.3.7 * schizosaccharomyces pombe 98000.0 2 PMID:16233628 -1.5.4.1 * drosophila melanogaster 56000.0 4 PMID:16712527;PMID:6438092 -1.5.5.1 * bos taurus 66000.0 2 PMID:925004 -1.5.5.1 * cereibacter sphaeroides 60000.0 1 PMID:18069858 -1.5.5.1 * homo sapiens 67000.0 3 PMID:12049629;PMID:8306995 -1.5.5.1 * sus scrofa 69000.0 1 PMID:4052375 -1.5.5.2 * escherichia coli 293000.0 4 PMID:15449943;PMID:1618807;PMID:355248 -1.5.5.2 * mycobacterium tuberculosis 37000.0 1 PMID:23834473 -1.5.5.2 * pyrococcus horikoshii 440000.0 3 PMID:22089387 -1.5.5.2 * thermococcus profundus 160000.0 8 PMID:11282592;PMID:15064976 -1.5.5.2 * thermus thermophilus 78677.0 2 PMID:25545499 -1.5.7.1 * clostridium formicaceticum 237000.0 3 PMID:6381490 -1.5.7.1 * clostridium ljungdahlii 106000.0 1 PMID:34255221 -1.5.7.1 * neomoorella thermoacetica 32000.0 1 PMID:25002540 -1.5.8.1 * hyphomicrobium sp. 176000.0 4 PMID:454446;PMID:7556160 -1.5.8.2 * methylophilus methylotrophus 166000.0 3 PMID:7169636 -1.5.8.2 * methylotrophic bacterium 161000.0 1 PMID:4462741 -1.5.8.3 * homo sapiens 99510.0 2 PMID:10444331 -1.5.8.3 * pseudomonas aeruginosa 266000.0 1 PMID:406917 -1.5.8.3 * pseudomonas putida 170000.0 3 * -1.5.8.3 * rattus norvegicus 105000.0 2 PMID:3702694;PMID:6163777 -1.5.8.3 * sus scrofa 91000.0 1 PMID:6180732 -1.5.8.4 * chromohalobacter israelensis 79000.0 1 PMID:32631860 -1.5.8.4 * rattus norvegicus 97410.0 6 PMID:15358367;PMID:18423846;PMID:6159630;PMID:6163777 -1.5.8.4 * sus scrofa 93000.0 1 PMID:6180732 -1.5.98.1 * archaeoglobus fulgidus 140000.0 4 PMID:11265475;PMID:2743220;PMID:8481089 -1.5.98.1 * methanocaldococcus jannaschii 30305.0 1 PMID:11265475 -1.5.98.1 * methanopyrus kandleri 300000.0 7 PMID:11265475;PMID:8215796;PMID:9151968 -1.5.98.1 * methanosarcina barkeri 216000.0 4 PMID:11265475;PMID:1911853 -1.5.98.1 * methanothermobacter thermautotrophicus 36000.0 4 PMID:11265475;PMID:1991149;PMID:2743220;PMID:8481089 -1.5.98.1 * uncultured archaeon 30287.0 2 PMID:24707918 -1.5.98.2 * methanopyrus kandleri 300000.0 3 PMID:1953299;PMID:2379499 -1.5.98.2 * methanosarcina barkeri 38000.0 1 PMID:1911853 -1.5.98.2 * methanothermobacter thermautotrophicus 300000.0 5 PMID:1953299;PMID:2298726;PMID:2379499 -1.5.98.3 * methanolobus tindarius 120000.0 1 PMID:1735436 -1.5.98.3 * methanosarcina mazei 115000.0 1 PMID:10751389 -1.5.99.12 * arabidopsis thaliana 97000.0 17 PMID:12721786;PMID:20825956 -1.5.99.12 * catharanthus roseus 25100.0 1 * -1.5.99.12 * dendrobium huoshanense 60383.0 1 PMID:18649011 -1.5.99.12 * dendrobium hybrid cultivar 60400.0 1 PMID:12721786 -1.5.99.12 * hordeum vulgare 58800.0 3 PMID:12721786;PMID:15479228 -1.5.99.12 * lathyrus oleraceus 57966.0 1 * -1.5.99.12 * nostoc sp. 49800.0 1 PMID:12721786 -1.5.99.12 * oryza sativa 59100.0 4 PMID:12721786 -1.5.99.12 * rhodococcoides fascians 47900.0 1 PMID:12721786 -1.5.99.12 * triticum aestivum 60000.0 3 PMID:11168382 -1.5.99.12 * zea mays 94400.0 7 PMID:12721786;PMID:15272190;PMID:15927342;PMID:18571199 -1.5.99.13 * pyrobaculum islandicum 145000.0 3 PMID:11823469 -1.5.99.14 * pseudarthrobacter oxydans 120000.0 4 * -1.5.99.4 * paenarthrobacter nicotinovorans 290000.0 4 PMID:7815950;PMID:9878353 -1.5.99.4 * pseudarthrobacter oxydans 120000.0 4 * -1.5.99.5 * aminobacter aminovorans 550000.0 2 PMID:597255 -1.5.99.5 * bacterium at2 407000.0 2 * -1.5.99.6 * citrobacter freundii 65000.0 3 PMID:1369091 -1.5.99.6 * glycine max 130000.0 2 * -1.5.99.6 * pseudomonas aeruginosa 69850.0 3 PMID:16849793 -1.5.99.6 * serratia marcescens 79000.0 3 PMID:376502;PMID:4918845 -1.6.1.1 * azotobacter vinelandii 421000.0 7 PMID:39756;PMID:4404238;PMID:6840064;PMID:7140769;PMID:7398644;PMID:7460901 -1.6.1.1 * escherichia coli 53000.0 3 PMID:19725101;PMID:21545646 -1.6.1.1 * pseudomonas aeruginosa 6400000.0 4 PMID:4404238;PMID:6840064;PMID:7460901;PMID:823872;PMID:9098078 -1.6.1.1 * pseudomonas fluorescens 54000.0 2 PMID:4404238;PMID:6840064;PMID:7460901;PMID:823872;PMID:9098078 -1.6.1.3 * azotobacter vinelandii 421000.0 1 PMID:7460901 -1.6.2.2 * badhamia polycephala 29000.0 1 PMID:17341833 -1.6.2.2 * bos taurus 38400.0 3 PMID:6654871 -1.6.2.2 * brassica napus 35000.0 1 * -1.6.2.2 * canis lupus familiaris 31365.0 1 PMID:16814740 -1.6.2.2 * homo sapiens 36000.0 6 PMID:15302896;PMID:15858218;PMID:2500149;PMID:6841358 -1.6.2.2 * lathyrus oleraceus 135000.0 2 PMID:16665720 -1.6.2.2 * mucor racemosus 30000.0 1 PMID:19746258 -1.6.2.2 * musca domestica 33000.0 2 PMID:8936052 -1.6.2.2 * oryctolagus cuniculus 365000.0 7 PMID:175049;PMID:28780;PMID:672620;PMID:7096301;PMID:7986089 -1.6.2.2 * ovis aries 34000.0 1 PMID:10216966;PMID:2597703 -1.6.2.2 * phascolopsis gouldii 200000.0 2 PMID:10216966;PMID:2597703 -1.6.2.2 * propsilocerus akamusi 33200.0 1 PMID:25829149 -1.6.2.2 * rattus norvegicus 42800.0 10 PMID:15488472;PMID:18973815;PMID:18991555;PMID:4315302;PMID:7142181;PMID:7986089;PMID:8812833 -1.6.2.2 * saccharomyces cerevisiae 28000.0 2 PMID:14930 -1.6.2.2 * solanum tuberosum 44000.0 1 * -1.6.2.2 * sus scrofa 35000.0 5 PMID:19716516;PMID:6326802 -1.6.2.2 * tetrahymena pyriformis 22000.0 1 PMID:6807303 -1.6.2.2 * zea mays 44000.0 2 PMID:10024528 -1.6.2.4 * anopheles minimus 83000.0 3 PMID:17598560;PMID:18539133;PMID:20235118 -1.6.2.4 * bos taurus 76000.0 1 PMID:12481304 -1.6.2.4 * candida albicans 78000.0 1 PMID:19171935;PMID:19937842;PMID:20152939;PMID:20435019 -1.6.2.4 * candida tropicalis 76000.0 3 PMID:107026;PMID:3111296;PMID:6772182 -1.6.2.4 * centaurium erythraea 81000.0 3 PMID:19470102 -1.6.2.4 * chilo suppressalis 77600.0 2 PMID:24036507 -1.6.2.4 * coleus scutellarioides 78300.0 1 PMID:18982412 -1.6.2.4 * equus caballus 85000.0 1 PMID:2106448 -1.6.2.4 * gossypium hirsutum 78590.0 2 PMID:19883924 -1.6.2.4 * helianthus tuberosus 85000.0 2 PMID:2499315;PMID:3091006 -1.6.2.4 * homo sapiens 85000.0 4 PMID:108270;PMID:19077323;PMID:19171935;PMID:19937842;PMID:20152939;PMID:20435019;PMID:25196843;PMID:6175794 -1.6.2.4 * lodderomyces elongisporus 79000.0 1 PMID:6810895 -1.6.2.4 * malassezia globosa 80740.0 1 PMID:22297231 -1.6.2.4 * mesocricetus auratus 76000.0 1 PMID:3111296;PMID:6772182 -1.6.2.4 * mus musculus 62000.0 1 PMID:807209 -1.6.2.4 * musca domestica 85000.0 1 PMID:108270;PMID:6175794 -1.6.2.4 * nitrobacter winogradskyi 70000.0 2 PMID:14931 -1.6.2.4 * oryctolagus cuniculus 79000.0 5 PMID:2109611;PMID:2157416;PMID:4145653 -1.6.2.4 * petunia x hybrida 84000.0 1 PMID:7991686 -1.6.2.4 * phanerodontia chrysosporium 88200.0 4 PMID:12437968 -1.6.2.4 * rattus norvegicus 85000.0 7 PMID:19077323;PMID:19161969;PMID:19171935;PMID:19937842;PMID:20152939;PMID:20435019;PMID:2106448;PMID:2708380;PMID:9390 -1.6.2.4 * rhizopus stolonifer 78000.0 1 PMID:12429143 -1.6.2.4 * saccharomyces cerevisiae 85000.0 6 PMID:120699;PMID:14931;PMID:20624491;PMID:9468503 -1.6.2.4 * spodoptera eridania 70000.0 1 PMID:117798 -1.6.2.4 * starmerella apicola 76068.0 1 PMID:22526787 -1.6.2.4 * sus scrofa 400000.0 3 PMID:3125159;PMID:3926000;PMID:4153561;PMID:4374137 -1.6.2.4 * trametes versicolor 81000.0 2 PMID:12226721 -1.6.2.4 * trypanosoma cruzi 100000.0 5 PMID:18455247;PMID:3923933 -1.6.2.5 * cereibacter sphaeroides 43000.0 1 PMID:4385431 -1.6.2.6 * glycine max 110000.0 6 PMID:10729615;PMID:11607104;PMID:11788775;PMID:16668174;PMID:6539095 -1.6.2.6 * vigna unguiculata 110000.0 3 PMID:10729615;PMID:11607104;PMID:16668174 -1.6.3.1 * canis lupus familiaris 180000.0 1 PMID:10806195 -1.6.3.1 * corynebacterium glutamicum 55000.0 1 PMID:11731134 -1.6.3.1 * homo sapiens 190000.0 8 PMID:10601291;PMID:10806195;PMID:11443211;PMID:11822874;PMID:15591162;PMID:20731357;PMID:20942471 -1.6.3.1 * mus musculus 28000.0 1 PMID:20224597 -1.6.3.1 * saccharolobus solfataricus 38000.0 2 PMID:10625624 -1.6.3.1 * sus scrofa 180000.0 4 PMID:10601291;PMID:10806195 -1.6.3.1 * thermococcus kodakarensis 330000.0 6 PMID:24723088 -1.6.3.2 * giardia duodenalis 214000.0 3 PMID:26685698;PMID:8898901 -1.6.3.2 * thermococcus kodakarensis 330000.0 4 PMID:18959761;PMID:23453203;PMID:24723088 -1.6.3.2 * thermococcus profundus 300000.0 4 PMID:18959761;PMID:20213313;PMID:23453203 -1.6.3.3 * acidianus ambivalens 70000.0 1 PMID:9480823 -1.6.3.3 * archaeoglobus fulgidus 178000.0 9 PMID:11717257;PMID:12823559 -1.6.3.3 * brevibacterium sp. 102000.0 2 PMID:18521590 -1.6.3.3 * methanocaldococcus jannaschii 86000.0 2 PMID:19118348 -1.6.3.3 * pseudothermotoga hypogea 100000.0 2 PMID:11722568;PMID:15912375 -1.6.3.3 * pyrococcus furiosus 97100.0 2 PMID:11722568;PMID:15912375 -1.6.3.3 * pyrococcus horikoshii 84000.0 2 * -1.6.3.3 * saccharolobus solfataricus 35000.0 1 PMID:8867896 -1.6.3.3 * streptococcus mutans 220000.0 3 PMID:7765479;PMID:8254304 -1.6.3.3 * sulfolobus acidocaldarius 27000.0 1 PMID:8867896 -1.6.3.3 * thermotoga maritima 90000.0 3 PMID:17293421 -1.6.3.4 * anaerocolumna aminovalerica 180000.0 1 PMID:15014929 -1.6.3.4 * enterococcus faecalis 60000.0 2 PMID:3082630 -1.6.3.4 * lacticaseibacillus rhamnosus 100000.0 2 PMID:22326164;PMID:22418266 -1.6.3.4 * levilactobacillus brevis 196000.0 2 PMID:16511087 -1.6.3.4 * streptococcus mutans 50000.0 2 PMID:8254304;PMID:8824824 -1.6.3.4 * streptococcus pyogenes 100000.0 2 PMID:22326164;PMID:22418266 -1.6.5.10 * escherichia coli 42000.0 2 PMID:8611590 -1.6.5.10 * homo sapiens 100000.0 2 PMID:19000905 -1.6.5.10 * kluyveromyces marxianus 84000.0 2 PMID:14536026 -1.6.5.10 * microcystis aeruginosa 66070.0 3 * -1.6.5.10 * spinacia oleracea 40000.0 1 * -1.6.5.2 * archaeoglobus fulgidus 89000.0 4 PMID:16672604 -1.6.5.2 * beta vulgaris 86000.0 2 PMID:8798503 -1.6.5.2 * bos taurus 52000.0 1 * -1.6.5.2 * clostridium tyrobutyricum 60000.0 1 PMID:7407710 -1.6.5.2 * corynebacterium glutamicum 55000.0 1 PMID:11731134 -1.6.5.2 * cupriavidus pinatubonensis jmp134 21000.0 1 PMID:18165297 -1.6.5.2 * escherichia coli 79000.0 3 PMID:16672604 -1.6.5.2 * gammarus pulex 60000.0 1 PMID:14567578 -1.6.5.2 * glycine max 61600.0 2 PMID:7603972 -1.6.5.2 * halobacterium salinarum 36000.0 1 PMID:5027737 -1.6.5.2 * hevea brasiliensis 83000.0 2 PMID:12169304 -1.6.5.2 * homo sapiens 60000.0 4 PMID:18264564;PMID:7527260;PMID:9367528 -1.6.5.2 * mus musculus 52000.0 3 PMID:2418014;PMID:7527260 -1.6.5.2 * phanerodontia chrysosporium 69000.0 2 PMID:16535104 -1.6.5.2 * rattus norvegicus 61000.0 7 PMID:18418895;PMID:2500115;PMID:486148;PMID:56919;PMID:7527260 -1.6.5.2 * ricinus communis 67000.0 4 * -1.6.5.2 * triphysaria versicolor 25000.0 1 * -1.6.5.4 * arabidopsis thaliana 54000.0 2 PMID:16146528 -1.6.5.4 * avicennia marina 50000.0 1 PMID:20600571 -1.6.5.4 * cucumis sativus 47300.0 2 PMID:15272189;PMID:4055727 -1.6.5.4 * hordeum vulgare 40000.0 1 PMID:16341544 -1.6.5.4 * ipomoea batatas 14000.0 2 PMID:18393437 -1.6.5.4 * lathyrus oleraceus 47350.0 2 PMID:16055677;PMID:7983054 -1.6.5.4 * neurospora crassa 66000.0 1 PMID:4405497 -1.6.5.4 * nicotiana langsdorffii x nicotiana sanderae 40000.0 2 PMID:15284496 -1.6.5.4 * oryctolagus cuniculus 31000.0 1 PMID:15642324 -1.6.5.4 * pleurotus ostreatus 127000.0 2 * -1.6.5.4 * solanum lycopersicum 53000.0 1 PMID:20230481 -1.6.5.4 * solanum tuberosum 54000.0 3 PMID:12228637;PMID:24240368 -1.6.5.4 * spinacia oleracea 53000.0 2 PMID:15849415 -1.6.5.5 * arabidopsis thaliana 83200.0 2 PMID:10848984 -1.6.5.5 * camelus dromedarius 140000.0 2 PMID:1420281;PMID:7488002 -1.6.5.5 * cavia porcellus 140000.0 2 PMID:1420281;PMID:7488002 -1.6.5.5 * homo sapiens 36000.0 2 PMID:17497241 -1.6.5.5 * saccharomyces cerevisiae 70000.0 2 PMID:17497241 -1.6.5.5 * staphylococcus aureus 36300.0 1 PMID:12624201 -1.6.5.5 * synechocystis sp. 108000.0 2 PMID:22304305 -1.6.5.6 * burkholderia sp. sj98 21000.0 1 PMID:24376843 -1.6.5.6 * mucor ambiguus 54000.0 3 PMID:3286260 -1.6.5.6 * pseudomonas sp. wbc-3 25000.0 1 PMID:19218392 -1.6.5.6 * zea mays 23200.0 1 PMID:15964037 -1.6.5.7 * burkholderia cepacia 50000.0 2 PMID:9721310 -1.6.5.9 * arum maculatum 55000.0 3 PMID:6745260 -1.6.5.9 * saccharomyces cerevisiae 53000.0 2 PMID:20192260;PMID:3138118 -1.6.5.9 * solanum tuberosum 65000.0 4 PMID:10571867 -1.6.5.9 * yarrowia lipolytica 65800.0 4 PMID:10381390;PMID:17133620;PMID:19038229 -1.6.99.1 * bacillus subtilis 374000.0 10 PMID:12660247;PMID:15249051 -1.6.99.1 * candida macedoniensis 45890.0 2 PMID:12596862 -1.6.99.1 * saccharomyces pastorianus 50000.0 2 * -1.6.99.1 * xenopus laevis 235000.0 1 PMID:10994786 -1.6.99.1 * zymomonas mobilis 41700.0 2 * -1.7.1.1 * arabidopsis thaliana 102000.0 1 PMID:15897195 -1.7.1.1 * bradyrhizobium sp. 720000.0 4 * -1.7.1.1 * chlorella vulgaris 375000.0 8 PMID:165192;PMID:3015963;PMID:3510207;PMID:500668;PMID:7202004 -1.7.1.1 * cucurbita maxima 230000.0 2 PMID:4038708 -1.7.1.1 * emiliania huxleyi 514000.0 2 PMID:12925915 -1.7.1.1 * glycine max 330000.0 2 PMID:7208 -1.7.1.1 * gracilaria tenuistipitata 440000.0 2 PMID:12083765 -1.7.1.1 * hordeum vulgare 225000.0 8 PMID:225231 -1.7.1.1 * pyropia yezoensis 220000.0 2 * -1.7.1.1 * rhodobacter capsulatus 147000.0 4 PMID:9305729 -1.7.1.1 * skeletonema costatum 110000.0 1 PMID:12232038 -1.7.1.1 * spinacia oleracea 270000.0 3 PMID:12139973;PMID:16663994 -1.7.1.1 * triticum aestivum 202000.0 1 * -1.7.1.1 * zea mays 202000.0 2 PMID:15897195 -1.7.1.10 * rhodobacter capsulatus 57800.0 2 PMID:15322098 -1.7.1.11 * rattus norvegicus 370000.0 2 PMID:3152268 -1.7.1.12 * oryctolagus cuniculus 34000.0 1 PMID:4074379 -1.7.1.13 * pectobacterium carotovorum subsp. carotovorum 62000.0 1 * -1.7.1.13 * vibrio cholerae 67900.0 2 PMID:20875425 -1.7.1.14 * aspergillus oryzae 45690.0 2 PMID:15502348 -1.7.1.14 * cutaneotrichosporon cutaneum 45200.0 1 PMID:18433626 -1.7.1.14 * fusarium oxysporum 46000.0 2 PMID:11752781;PMID:15598501 -1.7.1.15 * escherichia coli 90000.0 5 PMID:1435259;PMID:2993824;PMID:6297458;PMID:7030314 -1.7.1.15 * rhodobacter capsulatus 90000.0 2 PMID:16897035 -1.7.1.16 * ectopseudomonas oleovorans 33000.0 2 PMID:7601851 -1.7.1.16 * pseudomonas sp. hk-6 27000.0 1 * -1.7.1.17 * bacillus smithii 48000.0 1 PMID:32801174 -1.7.1.17 * bacillus sp. b29 48000.0 1 PMID:17546472;PMID:31615666 -1.7.1.17 * chromobacterium violaceum 48000.0 1 PMID:17546472;PMID:31615666 -1.7.1.17 * enterococcus faecalis 43000.0 1 PMID:15003265 -1.7.1.17 * escherichia coli 42000.0 2 * -1.7.1.17 * geobacillus stearothermophilus 48000.0 1 PMID:19997911 -1.7.1.17 * lysinibacillus sphaericus 29000.0 1 PMID:24068503 -1.7.1.2 * [candida] nitratophila 365000.0 2 * -1.7.1.2 * chlorolobion braunii 467400.0 1 PMID:7195400;PMID:7200426 -1.7.1.2 * rhodotorula glutinis 230000.0 4 PMID:16097946;PMID:18182 -1.7.1.2 * triticale sp. 190000.0 1 * -1.7.1.3 * aspergillus nidulans 200000.0 6 PMID:4153024;PMID:4396143;PMID:7042701 -1.7.1.3 * funaria hygrometrica 450000.0 2 * -1.7.1.3 * fusarium oxysporum 214000.0 1 PMID:24610039 -1.7.1.3 * neurospora crassa 290000.0 10 PMID:26408;PMID:4275465;PMID:4388959 -1.7.1.3 * ogataea angusta 204000.0 2 PMID:15897195 -1.7.1.4 * azotobacter chroococcum 67000.0 1 PMID:4147887 -1.7.1.4 * escherichia coli 190000.0 2 PMID:217342 -1.7.1.4 * neurospora crassa 290000.0 3 PMID:4154942;PMID:6457037 -1.7.1.6 * bacillus amyloliquefaciens 60000.0 1 PMID:18034237 -1.7.1.6 * bacillus sp. (in: firmicutes) 62000.0 6 PMID:11134015;PMID:14766562;PMID:15003265;PMID:16611136 -1.7.1.6 * bacillus sp. b29 23000.0 2 PMID:18337254;PMID:19420689 -1.7.1.6 * bacillus velezensis 69900.0 1 PMID:33289153 -1.7.1.6 * brevibacillus laterosporus 58000.0 1 PMID:17601730 -1.7.1.6 * brevundimonas subvibrioides 30000.0 1 * -1.7.1.6 * cereibacter sphaeroides 44000.0 3 PMID:15212802;PMID:16611136 -1.7.1.6 * clostridium perfringens 90400.0 2 PMID:22182443 -1.7.1.6 * ectopseudomonas oleovorans 29000.0 1 PMID:23768111 -1.7.1.6 * enterococcus faecalis 46000.0 5 PMID:15003265;PMID:16611136;PMID:16684776;PMID:18757799 -1.7.1.6 * enterococcus faecium 23000.0 2 PMID:19741272 -1.7.1.6 * escherichia coli 53000.0 10 PMID:16611136;PMID:16684776;PMID:18337254;PMID:19420689;PMID:23089953;PMID:8112774 -1.7.1.6 * geobacillus stearothermophilus 46000.0 2 PMID:19997911 -1.7.1.6 * halomonas elongata 44000.0 1 PMID:30132989 -1.7.1.6 * pantoea agglomerans 28000.0 1 PMID:12706351 -1.7.1.6 * pigmentiphaga kullae 22000.0 5 PMID:12719939;PMID:15870453;PMID:16611136;PMID:20233432 -1.7.1.6 * pseudomonas aeruginosa 29000.0 1 * -1.7.1.6 * pseudomonas sp. 32000.0 4 PMID:6742955;PMID:7160382 -1.7.1.6 * pseudomonas sp. b1 29000.0 1 * -1.7.1.6 * rattus norvegicus 52000.0 2 PMID:108265 -1.7.1.6 * shewanella oneidensis 27000.0 1 PMID:23089953 -1.7.1.6 * shewanella sp. ifn4 33000.0 1 * -1.7.1.6 * shigella dysenteriae 28000.0 3 PMID:16611136 -1.7.1.6 * staphylococcus aureus 85000.0 3 PMID:12719939;PMID:15870453;PMID:16611136 -1.7.1.6 * xenophilus azovorans 30280.0 4 PMID:12147495;PMID:16611136 -1.7.1.7 * artemia salina 250000.0 1 PMID:4151342 -1.7.1.7 * bos taurus 90000.0 1 PMID:4147285 -1.7.1.7 * escherichia coli 156000.0 8 PMID:21298178;PMID:2904262;PMID:3005121 -1.7.1.7 * homo sapiens 170000.0 4 PMID:12009299;PMID:12669231;PMID:218932 -1.7.1.7 * salmonella enterica subsp. enterica serovar typhimurium 45000.0 1 * -1.7.1.7 * trypanosoma brucei 494000.0 1 PMID:32296055 -1.7.1.9 * mus musculus 200000.0 1 PMID:1370076 -1.7.2.1 * achromobacter cycloclastes 105000.0 3 PMID:11418554 -1.7.2.1 * achromobacter xylosoxidans 103000.0 3 PMID:11418554 -1.7.2.1 * alcaligenes sp. 79000.0 2 PMID:4086480;PMID:6501252 -1.7.2.1 * bradyrhizobium sp. ors 375 391000.0 2 PMID:32255260 -1.7.2.1 * cereibacter sphaeroides 80000.0 1 * -1.7.2.1 * cupriavidus necator 113000.0 2 PMID:16887530;PMID:8048839 -1.7.2.1 * fusarium oxysporum 900000.0 5 PMID:11418554;PMID:19270125 -1.7.2.1 * haloarcula marismortui 167000.0 2 PMID:11418554 -1.7.2.1 * haloferax denitrificans 127000.0 2 PMID:11418554 -1.7.2.1 * haloferax mediterranei 103000.0 3 PMID:23499847 -1.7.2.1 * hydrogenobacter thermophilus 75000.0 2 PMID:16781467 -1.7.2.1 * hyphomicrobium denitrificans 400000.0 3 PMID:12121770;PMID:15583395 -1.7.2.1 * nitrososphaera viennensis 105000.0 1 PMID:30318500 -1.7.2.1 * paracoccus denitrificans 130000.0 1 PMID:4309366 -1.7.2.1 * paracoccus pantotrophus 63022.0 1 PMID:12556530 -1.7.2.1 * paramagnetospirillum magnetotacticum 133000.0 2 PMID:7588814 -1.7.2.1 * pseudomonas aeruginosa 60204.0 1 PMID:7893816 -1.7.2.1 * pseudomonas chlororaphis 107000.0 2 PMID:15182351 -1.7.2.1 * pseudomonas nautica 617 131000.0 2 PMID:16887530;PMID:8048839 -1.7.2.1 * stutzerimonas stutzeri 60000.0 1 PMID:12802018 -1.7.2.1 * thiobacillus denitrificans 100000.0 2 PMID:8639023 -1.7.2.2 * aliivibrio fischeri 58000.0 2 PMID:2833168 -1.7.2.2 * desulfovibrio desulfuricans 66000.0 3 PMID:14511372;PMID:8798514 -1.7.2.2 * escherichia coli k-12 72000.0 5 PMID:2833168;PMID:3002798;PMID:9593308 -1.7.2.2 * nitratidesulfovibrio vulgaris 120000.0 2 PMID:16754983 -1.7.2.2 * nitratidesulfovibrio vulgaris str. hildenborough 760000.0 3 PMID:11004582 -1.7.2.2 * sulfurospirillum deleyianum 245000.0 3 PMID:7999130 -1.7.2.2 * thioalkalivibrio nitratireducens 390000.0 2 PMID:16500161;PMID:18298372 -1.7.2.2 * trichlorobacter lovleyi 56000.0 1 PMID:32518164 -1.7.2.2 * wolinella succinogenes 245000.0 4 PMID:2833168;PMID:7999130 -1.7.2.3 * escherichia coli 230000.0 6 PMID:12766163;PMID:16337610;PMID:3282544;PMID:3528139 -1.7.2.3 * proteus vulgaris 95000.0 1 PMID:6442555 -1.7.2.3 * rhodobacter capsulatus 85030.0 3 PMID:9165084 -1.7.2.3 * rhodospirillum rubrum 87000.0 4 * -1.7.2.3 * roseobacter denitrificans 172000.0 2 PMID:1337081;PMID:34284591 -1.7.2.3 * salmonella enterica subsp. enterica serovar typhimurium 332000.0 2 PMID:6350272 -1.7.2.3 * shewanella massilia 90000.0 9 PMID:12192070;PMID:9813127 -1.7.2.3 * shewanella sp. 84000.0 2 * -1.7.2.3 * uncultured bacterium 172000.0 1 PMID:1337081;PMID:34284591 -1.7.2.4 * achromobacter cycloclastes 72000.0 1 PMID:2154217 -1.7.2.4 * achromobacter xylosoxidans 134000.0 2 PMID:10092849 -1.7.2.4 * bradyrhizobium japonicum 71670.0 1 PMID:15028871 -1.7.2.4 * cereibacter sphaeroides 105000.0 4 PMID:10220576;PMID:14769874;PMID:9644245 -1.7.2.4 * hyphomicrobium denitrificans 105000.0 2 PMID:10747777;PMID:14769874;PMID:9644245 -1.7.2.4 * marinobacter nauticus 120000.0 3 PMID:10747777;PMID:14769874 -1.7.2.4 * paracoccus denitrificans 144000.0 4 PMID:3032972;PMID:6712645 -1.7.2.4 * paracoccus pantotrophus 115000.0 4 PMID:16234931;PMID:1899237;PMID:8383047;PMID:8639023 -1.7.2.4 * pseudomonas aeruginosa 120000.0 2 PMID:1899237;PMID:8383047;PMID:8639023 -1.7.2.4 * pseudomonas denitrificans (nom. rej.) 87000.0 1 PMID:6712645 -1.7.2.4 * pseudomonas fluorescens 120000.0 1 * -1.7.2.4 * pyrobaculum aerophilum 52900.0 3 PMID:20597980 -1.7.2.4 * shewanella denitrificans 130000.0 1 PMID:26885878 -1.7.2.4 * stutzerimonas stutzeri 130000.0 6 PMID:10747777;PMID:3000778;PMID:6712645 -1.7.2.4 * thiobacillus denitrificans 160000.0 2 PMID:1899237;PMID:8383047;PMID:8639023 -1.7.2.4 * wolinella succinogenes 162000.0 2 PMID:2536696 -1.7.2.5 * aspergillus oryzae 45689.0 2 PMID:15502348 -1.7.2.5 * cupriavidus necator 84500.0 2 PMID:10571051 -1.7.2.5 * cutaneotrichosporon cutaneum 43000.0 2 PMID:11389721;PMID:18433626 -1.7.2.5 * fusarium oxysporum 46000.0 1 PMID:15598501 -1.7.2.5 * halomonas halodenitrificans 42000.0 2 PMID:9374857 -1.7.2.5 * marinobacter nauticus 71800.0 4 PMID:19241371 -1.7.2.5 * nitratidesulfovibrio vulgaris 90160.0 2 PMID:15736966 -1.7.2.5 * paracoccus denitrificans 69500.0 7 PMID:18433624;PMID:8606159;PMID:9030265 -1.7.2.5 * roseobacter denitrificans 49000.0 4 PMID:12038974 -1.7.2.5 * stutzerimonas stutzeri 38000.0 2 PMID:11271799;PMID:8020468 -1.7.2.6 * methylococcus capsulatus 38900.0 2 PMID:7928947 -1.7.2.6 * nitrosococcus oceani 180000.0 1 PMID:21576859 -1.7.2.6 * nitrosomonas europaea 220000.0 19 PMID:11926822;PMID:12209257;PMID:12693206;PMID:15651867;PMID:1660304;PMID:20054133;PMID:227845;PMID:5758553;PMID:6274384;PMID:6289867;PMID:698180;PMID:8325841;PMID:9095195;PMID:9192739 -1.7.2.7 * candidatus kuenenia stuttgartensis 90000.0 3 PMID:25962914 -1.7.2.8 * candidatus brocadia anammoxidans 183000.0 3 PMID:10820012 -1.7.2.8 * candidatus brocadia fulgida 200700.0 1 PMID:33798263 -1.7.2.8 * candidatus jettenia caeni 130000.0 4 PMID:17172456;PMID:18397776 -1.7.2.8 * candidatus kuenenia stuttgartensis 201800.0 4 PMID:25962914;PMID:27317665 -1.7.2.8 * candidatus maribeggiatoa 54900.0 2 PMID:23220958 -1.7.2.8 * nitrosomonas europaea 67100.0 1 PMID:20054133 -1.7.2.9 * candidatus kuenenia stuttgartensis 184200.0 1 PMID:24302732 -1.7.2.9 * candidatus methylacidiphilum fumarolicum 500000.0 2 PMID:32913059 -1.7.3.1 * fusarium oxysporum 185000.0 5 PMID:15272176;PMID:34655320;PMID:9558355 -1.7.3.1 * pseudomonas aeruginosa 36700.0 1 PMID:23908035 -1.7.3.1 * streptomyces ansochromogenes 37000.0 1 PMID:18810541 -1.7.3.3 * [candida] sp. 140000.0 3 PMID:23237426;PMID:8203871 -1.7.3.3 * arthrobacter globiformis 120000.0 4 PMID:16233683;PMID:31253939 -1.7.3.3 * aspergillus flavus 137000.0 8 PMID:11856833;PMID:12149119;PMID:16478683;PMID:16545578;PMID:16665575;PMID:19586953;PMID:20445229;PMID:28667645 -1.7.3.3 * aspergillus niger 55300.0 3 * -1.7.3.3 * bacillus subtilis 98000.0 4 PMID:14728678;PMID:20168977 -1.7.3.3 * bos taurus 100000.0 1 PMID:5820720;PMID:7248313 -1.7.3.3 * cicer arietinum 128000.0 1 * -1.7.3.3 * cyberlindnera jadinii 120000.0 5 PMID:18437374;PMID:21573940;PMID:2625463;PMID:7200091 -1.7.3.3 * enterobacter cloacae 105000.0 1 * -1.7.3.3 * glycine max 141600.0 6 PMID:6685457;PMID:9125493;PMID:9709003 -1.7.3.3 * latimeria menadoensis 150000.0 1 PMID:30871218 -1.7.3.3 * metabacillus fastidiosus 151000.0 8 PMID:16689679;PMID:19734651;PMID:20530883;PMID:728443 -1.7.3.3 * microbacterium sp. 34000.0 1 * -1.7.3.3 * neurospora crassa 123000.0 2 PMID:6446884 -1.7.3.3 * phaseolus vulgaris 128000.0 2 PMID:16545578;PMID:16665575 -1.7.3.3 * pseudomonas aeruginosa 64000.0 1 PMID:15330267 -1.7.3.3 * puccinia recondita 125000.0 3 PMID:11910495 -1.7.3.3 * rattus norvegicus 230000.0 4 PMID:3182808;PMID:639984;PMID:727437 -1.7.3.3 * streptomyces cyanogenus 109000.0 2 PMID:7287651 -1.7.3.3 * sus scrofa 125000.0 2 PMID:4855918 -1.7.3.3 * triticum aestivum 140000.0 1 * -1.7.3.3 * uromyces phaseoli 124000.0 1 * -1.7.3.3 * uromyces viciae-fabae 124000.0 1 * -1.7.3.3 * vicia faba 122000.0 1 * -1.7.3.3 * vigna unguiculata 100000.0 2 PMID:5820720;PMID:7248313 -1.7.3.3 * yeast-like fungi 32880.0 1 PMID:10696593 -1.7.3.5 * penicillium atrovenetum 73000.0 2 PMID:3667582 -1.7.3.6 * paracoccus denitrificans 20000.0 1 PMID:8253206 -1.7.3.6 * pseudomonas sp. 19000.0 1 PMID:9082922 -1.7.5.1 * escherichia coli 230000.0 8 PMID:12910261;PMID:2139607;PMID:2674654 -1.7.5.1 * paracoccus denitrificans 200000.0 1 PMID:3371362 -1.7.5.1 * pseudomonas chlororaphis 129000.0 3 PMID:15804488 -1.7.5.2 * pyrobaculum aerophilum 127000.0 2 PMID:12799376 -1.7.5.2 * schinkia azotoformans 112000.0 3 PMID:11327887 -1.7.6.1 * rhodnius prolixus 20969.0 3 PMID:15170336;PMID:17428677 -1.7.7.1 * anabaena sp. 59650.0 1 PMID:11087941 -1.7.7.1 * chlamydomonas reinhardtii 86000.0 5 PMID:12060296;PMID:20039132;PMID:7766686 -1.7.7.1 * chlorolobion braunii 63000.0 1 * -1.7.7.1 * cucurbita pepo 63000.0 1 PMID:4390523 -1.7.7.1 * cyberlindnera jadinii 126000.0 3 PMID:8694757 -1.7.7.1 * haloferax mediterranei 74000.0 2 PMID:11267765 -1.7.7.1 * leptolyngbya laminosa 69000.0 2 PMID:2119228;PMID:2125945 -1.7.7.1 * limnospira platensis 52000.0 1 * -1.7.7.1 * lotus japonicus 64830.0 2 PMID:12060296;PMID:7766686 -1.7.7.1 * nicotiana tabacum 63700.0 1 PMID:22238192 -1.7.7.1 * oryza sativa 61000.0 2 * -1.7.7.1 * pyropia yezoensis 63000.0 2 PMID:3163766;PMID:4390523 -1.7.7.1 * scenedesmus fuscus 63000.0 1 PMID:5068817 -1.7.7.1 * solanum lycopersicum 63000.0 2 * -1.7.7.1 * spinacia oleracea 86000.0 8 PMID:3163766;PMID:7487061;PMID:838704 -1.7.7.1 * vigna angularis 100000.0 4 * -1.7.7.2 * acinetobacter calcoaceticus 100000.0 1 * -1.7.7.2 * anabaena sp. 80000.0 1 PMID:16143847 -1.7.7.2 * azotobacter chroococcum 100000.0 1 * -1.7.7.2 * clostridium perfringens 90000.0 2 PMID:202590 -1.7.7.2 * gloeobacter violaceus 80000.0 1 PMID:16143847 -1.7.7.2 * haloferax denitrificans 380000.0 3 PMID:1654831 -1.7.7.2 * haloferax mediterranei 132000.0 3 PMID:11731152 -1.7.7.2 * haloferax volcanii 72000.0 1 PMID:28321615 -1.7.7.2 * leptolyngbya boryana 85000.0 2 * -1.7.7.2 * nostoc punctiforme 80000.0 1 PMID:16143847 -1.7.7.2 * rhodobacter capsulatus 185000.0 2 * -1.7.7.2 * synechococcus elongatus 80000.0 1 PMID:16143847 -1.7.7.2 * synechococcus elongatus pcc 7942 = fachb-805 75000.0 1 * -1.7.7.2 * synechococcus sp. 80000.0 4 PMID:14871493;PMID:15166246;PMID:16143847;PMID:8624415 -1.7.7.2 * synechocystis sp. 80000.0 1 PMID:16143847 -1.7.7.2 * thermosynechococcus sp. 80000.0 1 PMID:16143847 -1.7.7.2 * trichodesmium erythraeum 80000.0 1 PMID:16143847 -1.7.99.1 * aspergillus niger 320000.0 1 PMID:977555 -1.7.99.1 * cucurbita pepo 60000.0 2 PMID:4395427 -1.7.99.1 * pyrococcus furiosus 102600.0 4 PMID:19241093 -1.7.99.1 * spinacia oleracea 65000.0 2 * -1.8.1.10 * rattus norvegicus 42500.0 1 PMID:4151341 -1.8.1.10 * saccharomyces cerevisiae 108000.0 1 PMID:4390951 -1.8.1.10 * staphylococcus aureus 90000.0 2 PMID:9488708 -1.8.1.11 * asparagus officinalis 112000.0 4 PMID:180003;PMID:440099 -1.8.1.12 * crithidia fasciculata 110000.0 3 PMID:2669965;PMID:3718941 -1.8.1.12 * euglena gracilis 54000.0 1 PMID:9923598 -1.8.1.12 * leishmania amazonensis 69200.0 2 PMID:18060667 -1.8.1.12 * leishmania donovani 110000.0 4 PMID:15766869;PMID:7607216 -1.8.1.12 * leishmania infantum 60000.0 2 PMID:23744811;PMID:24039168 -1.8.1.12 * leishmania mexicana 53200.0 1 PMID:23703438 -1.8.1.12 * trypanosoma brucei 96000.0 4 PMID:19747949 -1.8.1.12 * trypanosoma congolense 110000.0 3 PMID:2669965;PMID:3167026 -1.8.1.12 * trypanosoma cruzi 103000.0 3 PMID:15922604;PMID:2669965;PMID:3549299 -1.8.1.13 * halobacterium salinarum 122000.0 2 PMID:2910862;PMID:3136140 -1.8.1.14 * borreliella burgdorferi 50000.0 1 PMID:16390443 -1.8.1.14 * staphylococcus aureus 51000.0 1 PMID:22954034 -1.8.1.15 * mycobacterium tuberculosis 137000.0 5 PMID:10512639;PMID:28499823;PMID:29377100 -1.8.1.16 * marichromatium gracile 98000.0 4 PMID:11399772;PMID:11807270 -1.8.1.17 * arthrobacter methylotrophus 53000.0 1 PMID:10896224 -1.8.1.17 * hyphomicrobium sulfonivorans 53000.0 1 PMID:10896224 -1.8.1.18 * pyrococcus furiosus 100000.0 3 PMID:17449625 -1.8.1.18 * thermococcus kodakarensis 330000.0 3 PMID:24723088 -1.8.1.19 * pyrococcus furiosus 90000.0 5 PMID:10968624;PMID:7961401 -1.8.1.2 * acidithiobacillus ferrooxidans 60000.0 1 PMID:18317695 -1.8.1.2 * desulfosarcina variabilis 208000.0 4 PMID:8399175 -1.8.1.2 * escherichia coli 670000.0 5 PMID:26088143;PMID:4144254 -1.8.1.2 * methanocaldococcus jannaschii 350000.0 2 PMID:16048999 -1.8.1.2 * saccharomyces cerevisiae 650000.0 6 PMID:4384979;PMID:6751400;PMID:6758854 -1.8.1.2 * salmonella enterica subsp. enterica serovar typhimurium 488000.0 1 PMID:2550423 -1.8.1.22 * allochromatium vinosum 173000.0 2 PMID:31854015;PMID:9493389 -1.8.1.22 * desulfosarcina variabilis 208000.0 2 PMID:8399175 -1.8.1.22 * desulfovibrio desulfuricans 200000.0 5 PMID:8521853 -1.8.1.22 * megalodesulfovibrio gigas 220000.0 1 PMID:7338517 -1.8.1.22 * nitratidesulfovibrio vulgaris 226000.0 2 PMID:24211572;PMID:4725615 -1.8.1.22 * pyrobaculum aerophilum 12700.0 1 PMID:11722571 -1.8.1.22 * pyrobaculum islandicum 170000.0 4 PMID:31854015;PMID:9493389 -1.8.1.22 * thermodesulfobacterium commune 167000.0 2 PMID:6826522 -1.8.1.4 * acetivibrio thermocellus 28206.0 1 PMID:18323661 -1.8.1.4 * acidianus ambivalens 107000.0 3 PMID:18312361 -1.8.1.4 * advenella mimigardefordensis 63489.0 1 PMID:20833784 -1.8.1.4 * aeromonas caviae 43000.0 1 PMID:18675788 -1.8.1.4 * ascaris suum 105000.0 3 PMID:1898934;PMID:2294086;PMID:2643922;PMID:507807;PMID:9217012;PMID:9858775 -1.8.1.4 * azotobacter vinelandii 100000.0 3 PMID:14645106;PMID:2643922;PMID:6404748;PMID:6468378;PMID:6896050;PMID:7011812;PMID:7052136 -1.8.1.4 * bacillus subtilis 110000.0 2 PMID:18391450;PMID:18845259;PMID:2269305;PMID:6409095;PMID:9217012;PMID:9858775 -1.8.1.4 * bos taurus 55000.0 1 PMID:15196936;PMID:2643922 -1.8.1.4 * clostridium cylindrosporum 105000.0 2 PMID:2294086;PMID:507807;PMID:9217012 -1.8.1.4 * clostridium kluyveri 110000.0 7 PMID:18323662;PMID:18391450;PMID:6409095;PMID:9858775 -1.8.1.4 * escherichia coli 88000.0 4 PMID:2643922;PMID:2687245;PMID:6404748;PMID:6468378;PMID:7011812 -1.8.1.4 * geobacillus stearothermophilus 54000.0 1 PMID:2643922 -1.8.1.4 * glycine max 50027.0 1 PMID:11788775 -1.8.1.4 * halobacterium salinarum 112000.0 4 PMID:2643922;PMID:3136140;PMID:6426463 -1.8.1.4 * haloferax volcanii 119000.0 2 PMID:6426463;PMID:8655478 -1.8.1.4 * homo sapiens 110000.0 3 PMID:12297006;PMID:17960497;PMID:18845259;PMID:2269305;PMID:6409095;PMID:9217012 -1.8.1.4 * lathyrus oleraceus 59000.0 5 PMID:2643922;PMID:8904806 -1.8.1.4 * lysinibacillus sphaericus 50000.0 1 PMID:28597164 -1.8.1.4 * malbranchea pulchella 102000.0 3 PMID:10974122;PMID:497161 -1.8.1.4 * mesocricetus auratus 56000.0 1 PMID:14645106;PMID:2643922;PMID:6896050;PMID:7052136 -1.8.1.4 * microbacterium luteolum 102000.0 3 PMID:20159566 -1.8.1.4 * moorella thermoacetica atcc 39073 28430.0 1 PMID:18323661 -1.8.1.4 * mycobacterium tuberculosis 50000.0 1 PMID:17652161 -1.8.1.4 * mycobacterium tuberculosis variant bovis bcg 50000.0 1 PMID:17652161 -1.8.1.4 * mycolicibacterium smegmatis 49342.0 1 PMID:9143318 -1.8.1.4 * natronobacterium gregoryi 119000.0 1 PMID:6426463 -1.8.1.4 * natronococcus occultus 120000.0 1 PMID:6426463 -1.8.1.4 * natronomonas pharaonis 112000.0 1 PMID:6426463 -1.8.1.4 * peptostreptococcus glycinophilus 105000.0 2 PMID:2294086;PMID:507807;PMID:9217012 -1.8.1.4 * plasmodium falciparum 140000.0 4 PMID:15612914;PMID:25387830 -1.8.1.4 * pseudomonas aeruginosa 57000.0 1 PMID:23071278 -1.8.1.4 * pseudomonas putida 125000.0 2 PMID:6373365 -1.8.1.4 * rattus norvegicus 98000.0 4 PMID:14645106;PMID:2643922;PMID:6896050;PMID:7052136 -1.8.1.4 * saccharomyces cerevisiae 117000.0 2 PMID:6404748;PMID:6468378;PMID:7011812 -1.8.1.4 * saccharomyces pastorianus 61000.0 1 PMID:4611884 -1.8.1.4 * salmonella enterica subsp. enterica serovar typhimurium 56000.0 1 PMID:14645106;PMID:2643922;PMID:6896050;PMID:7052136 -1.8.1.4 * starkeyomyces koorchalomoides 50000.0 1 PMID:19383527 -1.8.1.4 * streptococcus pneumoniae 61600.0 1 PMID:17690105 -1.8.1.4 * streptomyces peucetius 54000.0 1 PMID:19481152 -1.8.1.4 * streptomyces seoulensis 110000.0 2 PMID:18391450;PMID:1898934;PMID:507807;PMID:6409095;PMID:9858775 -1.8.1.4 * sus scrofa 115000.0 7 PMID:11231302;PMID:14695919;PMID:15038962;PMID:15196936;PMID:15710613;PMID:2643922 -1.8.1.4 * synechocystis sp. 105000.0 2 PMID:18845259;PMID:2269305;PMID:2294086;PMID:507807;PMID:6409095;PMID:9217012 -1.8.1.4 * syntrophotalea carbinolica 110000.0 2 PMID:1898934;PMID:507807;PMID:9858775 -1.8.1.4 * thermoplasma acidophilum 118000.0 1 * -1.8.1.4 * trypanosoma cruzi 55000.0 2 PMID:17017892;PMID:18845259;PMID:2269305;PMID:6409095;PMID:9217012 -1.8.1.5 * xanthobacter sp. 57000.0 1 PMID:10684609;PMID:11223527 -1.8.1.7 * acidithiobacillus ferrooxidans 100000.0 2 PMID:330529;PMID:4407347 -1.8.1.7 * amphiprora kufferathii 71000.0 2 PMID:18557912 -1.8.1.7 * anabaena sp. 104000.0 2 PMID:6425264 -1.8.1.7 * arabidopsis thaliana 120000.0 3 PMID:11052765;PMID:19451637;PMID:237922 -1.8.1.7 * badhamia polycephala 99200.0 3 PMID:14563169 -1.8.1.7 * bos taurus 118000.0 7 PMID:11885281;PMID:14606686;PMID:17410407;PMID:7316181 -1.8.1.7 * camelus dromedarius 105000.0 2 PMID:11052765;PMID:18508412;PMID:19451637;PMID:237922;PMID:330529;PMID:39757 -1.8.1.7 * chlamydomonas reinhardtii 127000.0 3 * -1.8.1.7 * colwellia psychrerythraea 95240.0 1 PMID:26101017 -1.8.1.7 * colwellia sp. 61000.0 1 PMID:18557912 -1.8.1.7 * cyberlindnera mrakii 123000.0 2 PMID:16539602;PMID:8782419 -1.8.1.7 * equus caballus 107000.0 2 PMID:11885281;PMID:8432383 -1.8.1.7 * escherichia coli 109000.0 7 PMID:18508412;PMID:2006135;PMID:2666188;PMID:3003504;PMID:330529;PMID:3311037;PMID:39757;PMID:4407347;PMID:6393625;PMID:9277 -1.8.1.7 * euglena gracilis 79000.0 3 PMID:1274;PMID:23305756;PMID:3109393;PMID:9923598 -1.8.1.7 * gallus gallus 100000.0 2 PMID:11885281;PMID:15858236 -1.8.1.7 * haemonchus contortus 134000.0 1 PMID:28456691 -1.8.1.7 * hemicentrotus pulcherrimus 102000.0 2 PMID:330529;PMID:4407347 -1.8.1.7 * homo sapiens 100000.0 6 PMID:11885281;PMID:1274;PMID:15858236;PMID:23305756;PMID:7032915;PMID:9923598 -1.8.1.7 * ipomoea batatas 54800.0 2 PMID:19358534 -1.8.1.7 * lathyrus oleraceus 156000.0 3 PMID:16539602;PMID:16665034;PMID:8782419 -1.8.1.7 * limnospira maxima 177000.0 4 PMID:3089164 -1.8.1.7 * medicago sativa 140000.0 3 PMID:16667283 -1.8.1.7 * meriones unguiculatus 120000.0 2 PMID:6638490 -1.8.1.7 * moniezia expansa 114000.0 2 PMID:7788561 -1.8.1.7 * mus musculus 105000.0 2 PMID:18508412;PMID:23124348;PMID:24431548;PMID:330529;PMID:39757 -1.8.1.7 * neospora caninum 104000.0 1 PMID:34310993 -1.8.1.7 * nicotiana tabacum 55000.0 3 PMID:19043665 -1.8.1.7 * oncorhynchus mykiss 105000.0 2 PMID:18508412;PMID:330529;PMID:39757 -1.8.1.7 * onobrychis viciifolia 149000.0 3 PMID:16667283 -1.8.1.7 * oryctolagus cuniculus 108000.0 3 PMID:11885281;PMID:507842 -1.8.1.7 * oryza sativa 106000.0 4 PMID:23124348;PMID:24431548;PMID:330529;PMID:34310993;PMID:39757;PMID:4407347 -1.8.1.7 * ovis aries 116000.0 3 PMID:11885281;PMID:2737302 -1.8.1.7 * phaeodactylum tricornutum 118000.0 5 PMID:19664954 -1.8.1.7 * phycomyces blakesleeanus 100000.0 2 PMID:2006135;PMID:2666188;PMID:3003504;PMID:9277 -1.8.1.7 * pibocella sp. 90000.0 1 PMID:18557912 -1.8.1.7 * planiliza haematocheilus 55430.0 1 PMID:32735957 -1.8.1.7 * plasmodium falciparum 110000.0 1 PMID:11052765;PMID:24431548;PMID:8631352 -1.8.1.7 * psychrobacter sp. ant206 53500.0 1 PMID:31936518 -1.8.1.7 * rattus norvegicus 126000.0 6 PMID:11052765;PMID:11885281;PMID:19451637;PMID:20490902;PMID:237922;PMID:26820767;PMID:30506659 -1.8.1.7 * rhodospirillum rubrum 63000.0 1 PMID:4393659 -1.8.1.7 * saccharomyces cerevisiae 118000.0 1 * -1.8.1.7 * schistosoma mansoni 90000.0 1 PMID:18300227 -1.8.1.7 * setaria cervi 110000.0 3 PMID:11052765;PMID:1274;PMID:23124348;PMID:23305756;PMID:24431548;PMID:39757;PMID:8631352;PMID:9923598 -1.8.1.7 * spinacia oleracea 145000.0 3 PMID:237922;PMID:24414099 -1.8.1.7 * streptococcus thermophilus 48712.0 1 PMID:31546211 -1.8.1.7 * sulfitobacter sp. 79000.0 1 PMID:18557912 -1.8.1.7 * sus scrofa 103000.0 2 PMID:31912;PMID:496001 -1.8.1.7 * taenia crassiceps 136000.0 2 PMID:14668013 -1.8.1.7 * trachemys scripta 55000.0 1 PMID:17075686 -1.8.1.7 * triticum aestivum 150000.0 3 * -1.8.1.7 * triticum turgidum subsp. durum 110000.0 2 PMID:11052765;PMID:19451637;PMID:237922;PMID:24431548;PMID:8631352 -1.8.1.7 * vigna unguiculata 53600.0 1 PMID:17008354 -1.8.1.7 * xanthomonas campestris 50000.0 1 PMID:15883020 -1.8.1.8 * homo sapiens 34900.0 2 PMID:18628206 -1.8.1.8 * methanosarcina acetivorans 12000.0 1 PMID:26684934 -1.8.1.8 * mycobacterium tuberculosis 29000.0 2 PMID:17157031 -1.8.1.8 * priestia megaterium 122000.0 2 PMID:6401287 -1.8.1.8 * pyrococcus furiosus 26000.0 2 PMID:11398486 -1.8.1.8 * pyrococcus horikoshii 16500.0 1 PMID:16896527 -1.8.1.8 * saccharolobus solfataricus 25000.0 1 PMID:16930136 -1.8.1.9 * acidithiobacillus ferrooxidans 33000.0 1 PMID:19319598 -1.8.1.9 * aeropyrum pernix 75000.0 1 PMID:12423340;PMID:4149839 -1.8.1.9 * allochromatium vinosum 60000.0 2 PMID:6373736 -1.8.1.9 * apis cerana cerana 54240.0 1 PMID:20399281 -1.8.1.9 * arabidopsis thaliana 180000.0 6 PMID:19151130;PMID:19825629 -1.8.1.9 * babesia bovis 100000.0 1 PMID:10447675;PMID:24239559 -1.8.1.9 * bos taurus 120000.0 4 PMID:10447675;PMID:19059456;PMID:24239559;PMID:6933551;PMID:8577704;PMID:9556556 -1.8.1.9 * caenorhabditis elegans 55000.0 1 PMID:16780799;PMID:19766715 -1.8.1.9 * cereibacter sphaeroides 68000.0 2 PMID:11539727;PMID:2430804 -1.8.1.9 * chironomus riparius 54410.0 1 PMID:22056681 -1.8.1.9 * daucus carota 62000.0 2 PMID:11539727;PMID:2430804 -1.8.1.9 * deinococcus radiophilus 72200.0 2 PMID:21046342 -1.8.1.9 * drosophila melanogaster 63700.0 3 PMID:11796729;PMID:18986163 -1.8.1.9 * emiliania huxleyi 59000.0 2 PMID:18945673 -1.8.1.9 * entamoeba histolytica 78000.0 4 PMID:17448896;PMID:22967759 -1.8.1.9 * escherichia coli 75000.0 6 PMID:14245401;PMID:2989245;PMID:8664260 -1.8.1.9 * euglena gracilis 185000.0 1 PMID:675 -1.8.1.9 * haemonchus contortus 134000.0 1 PMID:23248236 -1.8.1.9 * homo sapiens 160000.0 16 PMID:10462449;PMID:16217027;PMID:16458512;PMID:16618767;PMID:16780799;PMID:19059456;PMID:19766715;PMID:20810785;PMID:20851179;PMID:21172426;PMID:2844280;PMID:6933551;PMID:6950391;PMID:7159551;PMID:8343516;PMID:8577704;PMID:9177183;PMID:9556556 -1.8.1.9 * hordeum vulgare 200000.0 3 PMID:21456578 -1.8.1.9 * leptospira biflexa serovar patoc 70000.0 1 PMID:14522589;PMID:15667938;PMID:27178006 -1.8.1.9 * leptospira interrogans serovar copenhageni 70000.0 1 PMID:14522589;PMID:15667938;PMID:27178006 -1.8.1.9 * medicago truncatula 150000.0 5 PMID:17185738 -1.8.1.9 * meleagris gallopavo 88000.0 1 * -1.8.1.9 * mus musculus 67000.0 4 PMID:11060283;PMID:16217027;PMID:16458512;PMID:17229725;PMID:18986163 -1.8.1.9 * plasmodium berghei 22000.0 1 * -1.8.1.9 * plasmodium falciparum 55000.0 1 PMID:16217027;PMID:16458512 -1.8.1.9 * pyrococcus furiosus 27000.0 1 PMID:14522589 -1.8.1.9 * pyrococcus horikoshii 70000.0 1 PMID:14522589;PMID:15667938;PMID:27178006 -1.8.1.9 * rattus norvegicus 250000.0 14 PMID:11060283;PMID:16618767;PMID:16780799;PMID:19146949;PMID:19766715;PMID:20494123;PMID:20536427;PMID:20609907;PMID:20810785;PMID:20851179;PMID:6950391;PMID:7159551;PMID:8577704;PMID:9177183 -1.8.1.9 * saccharolobus solfataricus 70000.0 2 PMID:14522589;PMID:15667938;PMID:27178006 -1.8.1.9 * saccharomyces cerevisiae 75000.0 3 PMID:12423340;PMID:20235561;PMID:4149839 -1.8.1.9 * schistosoma mansoni 90000.0 2 PMID:18300227;PMID:20659890 -1.8.1.9 * solanum lycopersicum 36500.0 1 PMID:22027005 -1.8.1.9 * spinacia oleracea 68000.0 2 PMID:3190242 -1.8.1.9 * taenia crassiceps 136000.0 2 PMID:14668013 -1.8.1.9 * thermotoga maritima 67000.0 2 PMID:20061476 -1.8.1.9 * triticum aestivum 65000.0 2 PMID:12106017 -1.8.2.1 * acidithiobacillus ferrooxidans 41500.0 1 PMID:5142118 -1.8.2.1 * acidithiobacillus thiooxidans 400000.0 4 * -1.8.2.1 * ancylobacter novellus 46000.0 8 PMID:10788424;PMID:11557133;PMID:12372602;PMID:12517167;PMID:16893171;PMID:6853504 -1.8.2.1 * chlorobaculum tepidum 48000.0 3 PMID:20378984 -1.8.2.1 * cupriavidus necator h16 40700.0 2 PMID:18174144 -1.8.2.1 * delftia acidovorans sph-1 67000.0 3 PMID:18174144 -1.8.2.1 * homo sapiens 101000.0 2 PMID:16475804 -1.8.2.1 * paracoccus pantotrophus 190000.0 5 PMID:10795683 -1.8.2.1 * paracoccus versutus 44000.0 1 * -1.8.2.1 * sinorhizobium meliloti 78000.0 1 PMID:24892218 -1.8.2.1 * thiobacillus thioparus 54000.0 1 PMID:11557133;PMID:5438321 -1.8.2.2 * acidiphilium acidophilum 102000.0 3 * -1.8.2.2 * acidithiobacillus ferrooxidans 45000.0 3 PMID:17454821;PMID:23064330 -1.8.2.2 * alcaligenes sp. 90000.0 1 PMID:5018699 -1.8.2.2 * allochromatium vinosum 30000.0 3 PMID:16995898;PMID:22779704 -1.8.2.2 * nitratidesulfovibrio vulgaris 89000.0 2 PMID:2993256 -1.8.2.2 * rhodopila globiformis 180000.0 1 * -1.8.2.2 * thermithiobacillus tepidarius 138000.0 2 * -1.8.2.2 * thiobacillus sp. 120000.0 3 PMID:9082913 -1.8.2.2 * thiobacillus thioparus 115000.0 1 PMID:5438323 -1.8.2.3 * allochromatium vinosum 101000.0 15 PMID:222744;PMID:7939681;PMID:8880899 -1.8.2.3 * chlorobaculum thiosulfatiphilum 58000.0 3 * -1.8.2.3 * ectothiorhodospira shaposhnikovii 46000.0 2 PMID:10809687 -1.8.2.3 * paracoccus pantotrophus 42832.0 3 PMID:15544340 -1.8.2.3 * thioalkalivibrio paradoxus 50000.0 1 PMID:33838635 -1.8.2.3 * thiobacillus sp. 40000.0 2 PMID:9094227 -1.8.2.4 * rhodovulum sulfidophilum 152000.0 13 PMID:12067345;PMID:8706745 -1.8.2.5 * megalodesulfovibrio gigas 220000.0 1 * -1.8.2.5 * nitratidesulfovibrio vulgaris 16300.0 2 PMID:5573735 -1.8.2.6 * paracoccus pantotrophus 180000.0 1 PMID:15865447 -1.8.3.1 * arabidopsis thaliana 88000.0 8 PMID:11598126;PMID:16305246;PMID:16307306;PMID:16464145;PMID:17425719;PMID:17853359;PMID:28461726;PMID:33038689 -1.8.3.1 * bos taurus 120000.0 2 PMID:5100416 -1.8.3.1 * brachypodium distachyon 88000.0 1 PMID:28461726 -1.8.3.1 * capra hircus 113000.0 1 PMID:19239123 -1.8.3.1 * deinococcus radiodurans 44300.0 4 PMID:16385059 -1.8.3.1 * gallus gallus 55000.0 2 PMID:2687265;PMID:4342603 -1.8.3.1 * homo sapiens 101000.0 2 PMID:16475804 -1.8.3.1 * malva sylvestris 27000.0 1 * -1.8.3.1 * merluccius productus 120000.0 1 PMID:6252974 -1.8.3.1 * nicotiana tabacum 46000.0 1 PMID:11598126 -1.8.3.1 * populus trichocarpa 88000.0 1 PMID:28461726 -1.8.3.1 * rattus norvegicus 120000.0 3 PMID:7161265;PMID:721809 -1.8.3.1 * sinorhizobium meliloti 71000.0 3 PMID:21833314 -1.8.3.1 * solanum lycopersicum 88000.0 1 PMID:28461726 -1.8.3.1 * thermus thermophilus 39100.0 2 PMID:16830073 -1.8.3.1 * zea mays 45000.0 1 PMID:22693572 -1.8.3.2 * african swine fever virus 28000.0 2 PMID:16537584 -1.8.3.2 * arabidopsis thaliana 47000.0 4 PMID:14996837;PMID:16893552;PMID:23068612 -1.8.3.2 * aspergillus niger 55000.0 3 PMID:12176051 -1.8.3.2 * aspergillus oryzae 78000.0 5 PMID:20727152;PMID:21327412 -1.8.3.2 * aspergillus tubingensis 55000.0 1 PMID:29216817 -1.8.3.2 * autographa californica multiple nucleopolyhedrovirus 33000.0 1 PMID:21752922 -1.8.3.2 * bos taurus 90000.0 3 PMID:1123323;PMID:15671873;PMID:16438804;PMID:3048213 -1.8.3.2 * cavia porcellus 68000.0 1 PMID:15193418 -1.8.3.2 * gallus gallus 202000.0 4 PMID:12176051;PMID:12693953;PMID:8940019 -1.8.3.2 * homo sapiens 78000.0 3 PMID:14633699;PMID:8813713 -1.8.3.2 * mus musculus 66000.0 2 PMID:12354420;PMID:15671873;PMID:16438804 -1.8.3.2 * rattus norvegicus 85360.0 10 PMID:11278790;PMID:12176051;PMID:15116395;PMID:15916753;PMID:16160860;PMID:16806532;PMID:3657562;PMID:6251889 -1.8.3.2 * saccharomyces cerevisiae 48660.0 4 PMID:11885286;PMID:16407158 -1.8.3.2 * sus scrofa 120000.0 2 PMID:2871813 -1.8.3.2 * trypanosoma brucei 54300.0 2 PMID:20121244 -1.8.3.3 * african swine fever virus 28000.0 2 PMID:16537584 -1.8.3.3 * aspergillus oryzae 45000.0 2 PMID:20727152 -1.8.3.3 * penicillium sp. 95000.0 2 * -1.8.3.3 * rattus norvegicus 66000.0 1 PMID:7397095 -1.8.3.4 * hyphomicrobium sp. 50000.0 2 * -1.8.3.4 * hyphomicrobium sp. vs 200000.0 4 PMID:29064480 -1.8.3.4 * rhodococcus rhodochrous 64500.0 1 * -1.8.3.4 * thiobacillus thioparus 40000.0 2 * -1.8.3.5 * arabidopsis thaliana 67000.0 3 PMID:19969520 -1.8.3.5 * bos taurus 63000.0 1 PMID:16627894 -1.8.3.5 * homo sapiens 55300.0 1 PMID:19253276 -1.8.3.6 * arabidopsis thaliana 67000.0 3 PMID:19969520 -1.8.4.1 * aspergillus flavipes 80000.0 2 * -1.8.4.10 * allochromatium vinosum 29142.0 1 PMID:10939523 -1.8.4.10 * catharanthus roseus 51394.0 1 PMID:10082930 -1.8.4.10 * desulfovibrio aminophilus 75000.0 2 * -1.8.4.10 * physcomitrium patens 71000.0 2 PMID:24100135 -1.8.4.11 * bos taurus 25000.0 1 PMID:15680228 -1.8.4.11 * caenorhabditis elegans 29700.0 1 PMID:15639227 -1.8.4.11 * dickeya chrysanthemi 27000.0 2 PMID:12431100;PMID:15680228 -1.8.4.11 * drosophila melanogaster 25000.0 1 PMID:15680228 -1.8.4.11 * escherichia coli 25000.0 1 PMID:15680228 -1.8.4.11 * haemophilus influenzae 25000.0 1 PMID:15680228 -1.8.4.11 * helicobacter pylori 43000.0 2 PMID:15387818;PMID:15680228 -1.8.4.11 * homo sapiens 25000.0 2 PMID:15680228;PMID:21670260 -1.8.4.11 * leptospira interrogans 23000.0 2 PMID:33242654 -1.8.4.11 * mus musculus 25000.0 5 PMID:15680228;PMID:20510353;PMID:21696616 -1.8.4.11 * neisseria gonorrhoeae 57000.0 1 PMID:15680228 -1.8.4.11 * neisseria meningitidis 25000.0 2 PMID:11812798;PMID:15680228 -1.8.4.11 * nicotiana tabacum 21000.0 2 PMID:23552991 -1.8.4.11 * saccharomyces cerevisiae 25000.0 1 PMID:15680228 -1.8.4.11 * salmonella enterica subsp. enterica serovar typhimurium 26000.0 1 PMID:28941926 -1.8.4.11 * solanum lycopersicum 22000.0 2 PMID:22447340 -1.8.4.11 * streptococcus gordonii 25000.0 1 PMID:15680228 -1.8.4.11 * streptococcus pneumoniae 25000.0 1 PMID:15680228 -1.8.4.11 * trypanosoma brucei brucei 21000.0 1 PMID:28865997 -1.8.4.11 * trypanosoma cruzi 30000.0 4 PMID:20969952 -1.8.4.12 * acer pseudoplatanus 17000.0 2 PMID:33316974 -1.8.4.12 * arabidopsis thaliana 16860.0 4 PMID:19457862 -1.8.4.12 * carica papaya 16900.0 1 PMID:29373846 -1.8.4.12 * fagus sylvatica 17000.0 2 PMID:33401671 -1.8.4.12 * helicobacter pylori 43000.0 1 PMID:15387818 -1.8.4.12 * homo sapiens 21000.0 2 PMID:29420254;PMID:30545068 -1.8.4.12 * mus musculus 14000.0 3 PMID:12359247;PMID:20634897 -1.8.4.12 * mycolicibacterium smegmatis 15000.0 2 PMID:20006300 -1.8.4.12 * neisseria gonorrhoeae 57000.0 1 PMID:15680228 -1.8.4.12 * neisseria meningitidis 16374.0 1 PMID:11812798 -1.8.4.12 * nicotiana tabacum 14800.0 1 PMID:17673175 -1.8.4.12 * solanum lycopersicum 21200.0 1 PMID:23283574 -1.8.4.12 * trypanosoma brucei 20000.0 1 PMID:28865997 -1.8.4.13 * escherichia coli b 21000.0 1 PMID:6999943 -1.8.4.14 * neisseria meningitidis 36330.0 2 PMID:20489204 -1.8.4.14 * thermoplasma acidophilum 15924.0 1 PMID:25043974 -1.8.4.15 * escherichia coli 50000.0 1 PMID:1429594 -1.8.4.16 * escherichia coli 25000.0 1 PMID:11493705 -1.8.4.17 * aquifex aeolicus 450000.0 2 PMID:27284018 -1.8.4.2 * bos taurus 200000.0 11 PMID:3899711;PMID:4474022;PMID:536109;PMID:5587960;PMID:5689114;PMID:7236203;PMID:903355 -1.8.4.2 * chlamydomonas reinhardtii 52000.0 3 PMID:20406640 -1.8.4.2 * escherichia coli 41000.0 4 PMID:10841975;PMID:11732919;PMID:8016867;PMID:9654144 -1.8.4.2 * homo sapiens 54500.0 2 PMID:11106430;PMID:14871896 -1.8.4.2 * mus musculus 60000.0 1 PMID:6796117 -1.8.4.2 * mycobacterium tuberculosis 29000.0 4 PMID:17157031 -1.8.4.2 * rattus norvegicus 120000.0 4 PMID:4405719;PMID:4633483 -1.8.4.2 * streptococcus gordonii 20000.0 1 PMID:23615907 -1.8.4.3 * bos taurus 120000.0 1 PMID:5924646 -1.8.4.4 * saccharomyces cerevisiae 150000.0 1 PMID:5646485 -1.8.4.7 * rattus norvegicus 43000.0 2 PMID:6960894 -1.8.4.8 * bacillus subtilis 27000.0 1 PMID:14627706 -1.8.4.8 * escherichia coli 44000.0 2 PMID:2005873 -1.8.4.8 * synechococcus sp. 22635.0 1 PMID:1463852 -1.8.4.9 * arabidopsis thaliana 51300.0 8 PMID:31597378;PMID:8917599;PMID:8917600 -1.8.4.9 * archaeoglobus fulgidus 75000.0 2 PMID:16503650 -1.8.4.9 * catharanthus roseus 51390.0 2 PMID:10082930 -1.8.4.9 * glycine max 46000.0 1 PMID:17761201 -1.8.4.9 * lemna minor 91300.0 3 PMID:10625629 -1.8.4.9 * physcomitrium patens 50000.0 2 PMID:17519237 -1.8.4.9 * pseudomonas aeruginosa 29000.0 1 PMID:12492831 -1.8.4.9 * ulva intestinalis 45700.0 1 PMID:10889258 -1.8.5.1 * chlamydomonas reinhardtii 12000.0 1 PMID:20406640 -1.8.5.1 * euglena gracilis 28000.0 1 * -1.8.5.1 * homo sapiens 32000.0 1 PMID:8660320 -1.8.5.1 * ipomoea batatas 25000.0 2 PMID:18393437;PMID:18444663 -1.8.5.1 * oryza sativa 27000.0 5 PMID:16802688 -1.8.5.1 * pinus bungeana 29690.0 2 PMID:19903221 -1.8.5.1 * pleurotus ostreatus 86000.0 1 * -1.8.5.1 * populus tomentosa 40000.0 6 PMID:23661023 -1.8.5.1 * rattus norvegicus 48700.0 2 PMID:8809091;PMID:9211254 -1.8.5.1 * solanum tuberosum 23000.0 1 * -1.8.5.1 * spinacia oleracea 26000.0 3 PMID:11148269;PMID:3702678 -1.8.5.1 * taiwanofungus camphoratus 15000.0 2 PMID:19886686 -1.8.5.1 * triticum aestivum 24200.0 1 PMID:1007616 -1.8.5.2 * acidianus ambivalens 102000.0 7 PMID:15306018 -1.8.5.2 * acidithiobacillus ferrooxidans 25000.0 1 PMID:23064330 -1.8.5.3 * actinobacillus pleuropneumoniae 90000.0 1 PMID:14638764 -1.8.5.4 * acidianus ambivalens 48000.0 1 PMID:19438211 -1.8.5.4 * acidithiobacillus ferrooxidans 65000.0 3 PMID:17986789;PMID:20691146 -1.8.5.4 * aphanothece halophytica 57000.0 2 PMID:10852862 -1.8.5.4 * aquifex aeolicus 160000.0 5 PMID:17986789;PMID:20691146 -1.8.5.4 * caldivirga maquilingensis 89000.0 2 PMID:23103448;PMID:31816290 -1.8.5.4 * chlorobaculum tepidum 43500.0 1 PMID:27190141 -1.8.5.4 * pseudanabaena limnetica 57000.0 3 PMID:10852862;PMID:8119908 -1.8.5.4 * rhodobacter capsulatus 55000.0 4 PMID:10515944;PMID:12269799;PMID:9092526 -1.8.5.5 * salmonella enterica subsp. enterica serovar typhimurium 82700.0 3 PMID:7751291 -1.8.5.6 * allochromatium vinosum 171660.0 1 PMID:24030319 -1.8.5.6 * aquifex aeolicus 389000.0 2 PMID:32735861 -1.8.5.7 * natrialba magadii 77000.0 1 PMID:30713525 -1.8.5.7 * sphingobium chlorophenolicum 65000.0 2 PMID:20388120 -1.8.7.1 * allium cepa 71950.0 2 PMID:22944351 -1.8.7.1 * allium tuberosum 65000.0 2 PMID:9339549 -1.8.7.1 * brassica rapa 68000.0 4 PMID:9339549 -1.8.7.1 * brassica rapa subsp. chinensis 70000.0 2 PMID:9339549 -1.8.7.1 * escherichia coli 20000.0 2 PMID:11888295 -1.8.7.1 * glycine max 68000.0 2 PMID:12081370 -1.8.7.1 * lathyrus oleraceus 68000.0 1 PMID:12081370 -1.8.7.1 * limnospira platensis 120000.0 3 * -1.8.7.1 * methanocaldococcus jannaschii 350000.0 2 PMID:16048999 -1.8.7.1 * nicotiana benthamiana 78090.0 1 PMID:20047069 -1.8.7.1 * pyropia yezoensis 70000.0 2 * -1.8.7.1 * spinacia oleracea 137000.0 9 PMID:7104302 -1.8.7.1 * synechococcus elongatus 70000.0 1 PMID:29959913 -1.8.7.1 * zea mays 65000.0 1 PMID:16469743 -1.8.7.2 * chlamydomonas reinhardtii 13000.0 2 PMID:11538175 -1.8.7.2 * spinacia oleracea 31000.0 3 PMID:10996250;PMID:7628465;PMID:8055915 -1.8.7.2 * zea mays 12900.0 2 PMID:7916641;PMID:8898896 -1.8.98.1 * aquifex aeolicus 450000.0 2 PMID:27284018 -1.8.98.1 * desulfovibrio desulfuricans 61000.0 1 PMID:16388601 -1.8.98.1 * methanomassiliicoccus luminyensis 580000.0 1 PMID:26573766 -1.8.98.1 * methanosarcina barkeri 46000.0 4 PMID:8174566;PMID:9063468 -1.8.98.1 * methanosarcina thermophila 206000.0 4 PMID:9665708 -1.8.98.1 * methanothermobacter thermautotrophicus 550000.0 7 PMID:2121478;PMID:8119281 -1.8.98.2 * arabidopsis thaliana 13914.0 3 PMID:17217469;PMID:20176891 -1.8.98.2 * homo sapiens 14000.0 2 PMID:16565085;PMID:17176052 -1.8.98.2 * saccharomyces cerevisiae 15000.0 1 PMID:19801666 -1.8.98.3 * methanocaldococcus jannaschii 350000.0 2 PMID:16048999 -1.8.98.5 * methanobacterium thermoautotrophicus 250000.0 1 PMID:8119281 -1.8.98.6 * methanococcus maripaludis 500000.0 1 PMID:24039260 -1.8.98.7 * clostridium perfringens 45740.0 1 PMID:23477283 -1.8.98.8 * methanococcus aeolicus 78000.0 1 PMID:37403630 -1.8.98.8 * methanococcus voltae 82000.0 1 PMID:37403630 -1.8.99.2 * acidithiobacillus ferrooxidans 28000.0 1 PMID:19225840 -1.8.99.2 * arabidopsis thaliana 52000.0 1 PMID:18218969 -1.8.99.2 * archaebacterium 160000.0 2 PMID:11265481 -1.8.99.2 * archaeoglobus fulgidus 160000.0 7 PMID:11265481;PMID:16645317;PMID:8081492 -1.8.99.2 * bacillus subtilis 27000.0 1 PMID:14627706 -1.8.99.2 * chlorobium limicola 210000.0 1 * -1.8.99.2 * desulfobulbus propionicus 175000.0 1 * -1.8.99.2 * desulfomicrobium baculatum 170000.0 1 * -1.8.99.2 * desulfovibrio aminophilus 75000.0 2 * -1.8.99.2 * desulfovibrio desulfuricans 190000.0 7 PMID:10802060;PMID:16348440;PMID:2158885 -1.8.99.2 * desulfovibrio multispirans 170000.0 1 * -1.8.99.2 * megalodesulfovibrio gigas 400000.0 4 PMID:16348440;PMID:2158885 -1.8.99.2 * mycobacterium tuberculosis 600000.0 10 PMID:16262264;PMID:17023175 -1.8.99.2 * nitratidesulfovibrio vulgaris 439500.0 8 PMID:12006599;PMID:16348440;PMID:18997328;PMID:235533 -1.8.99.2 * prosthecochloris vibrioformis 180000.0 1 * -1.8.99.2 * pseudomonas aeruginosa 35430.0 3 PMID:15491155;PMID:16289027 -1.8.99.2 * thermodesulfobacterium thermophilum 175000.0 1 * -1.8.99.2 * thiobacillus denitrificans 200000.0 2 * -1.8.99.2 * thiobacillus thioparus 170000.0 1 * -1.8.99.2 * thiocapsa roseopersicina 180000.0 1 * -1.8.99.2 * ulva intestinalis 96000.0 6 PMID:16605269;PMID:17209569 -1.8.99.2 * uncultured desulfoarculaceae bacterium 70000.0 2 PMID:21392199 -1.9.6.1 * aliivibrio fischeri 100000.0 1 PMID:13412117 -1.9.6.1 * campylobacter jejuni 90000.0 2 PMID:15667303 -1.9.6.1 * cupriavidus necator 93309.0 5 PMID:8376334 -1.9.6.1 * escherichia coli 90000.0 2 PMID:17130127 -1.9.6.1 * escherichia coli k-12 90000.0 2 PMID:10234835 -1.9.6.1 * paracoccus pantotrophus 110000.0 5 PMID:17900239;PMID:8119278 -1.97.1.1 * azospira oryzae 420000.0 2 PMID:10542172 -1.97.1.1 * dechloromonas agitata 37000.0 1 PMID:16030201 -1.97.1.1 * dechlorosoma sp. 100000.0 2 PMID:15927421 -1.97.1.1 * proteus mirabilis 180000.0 4 * -1.97.1.1 * pseudomonas sp. 60000.0 3 PMID:15927421 -1.97.1.1 * stutzerimonas chloritidismutans 167000.0 12 PMID:12730181 -1.97.1.12 * chroococcidiopsis sp. ts-821 106800.0 1 PMID:24681621 -1.97.1.13 * pyrococcus furiosus 135000.0 2 PMID:16199576 -1.97.1.14 * enterobacter cloacae 600000.0 1 PMID:16885262 -1.97.1.4 * escherichia coli 34000.0 5 PMID:3053170;PMID:6364987;PMID:9478932 -1.97.1.4 * streptococcus equinus 30000.0 2 PMID:12089014 -1.97.1.4 * streptococcus mutans 40000.0 1 PMID:12930520 -1.97.1.9 * alcaligenes sp. 197000.0 1 * -1.97.1.9 * alcaligenes sp. ckcr-6a 197000.0 1 * -1.97.1.9 * enterobacter cloacae 600000.0 3 PMID:15667298;PMID:16885262 -1.97.1.9 * pseudomonas sp. 700000.0 1 PMID:19189180 -1.97.1.9 * sulfurospirillum barnesii 82000.0 6 PMID:10525169;PMID:15667298 -1.97.1.9 * thauera selenatis 250000.0 15 PMID:10525169;PMID:11914503;PMID:14730999;PMID:15667298;PMID:20547201;PMID:9295321 -2.1.1.1 * homo sapiens 30000.0 2 PMID:22628313;PMID:8182091 -2.1.1.1 * sus scrofa 30000.0 2 PMID:2963591 -2.1.1.10 * arabidopsis thaliana 36400.0 3 PMID:10747987 -2.1.1.10 * brassica oleracea 35400.0 1 PMID:17391716 -2.1.1.10 * escherichia coli 35000.0 5 PMID:10026151;PMID:26564203 -2.1.1.10 * homo sapiens 40000.0 1 PMID:18230605 -2.1.1.10 * saccharomyces cerevisiae 30000.0 1 * -2.1.1.100 * bos taurus 86000.0 3 PMID:9894153 -2.1.1.100 * homo sapiens 33000.0 1 PMID:22634004 -2.1.1.100 * oryctolagus cuniculus 180000.0 1 PMID:1322127 -2.1.1.100 * rattus norvegicus 98000.0 1 PMID:8043600 -2.1.1.100 * saccharomyces cerevisiae 36000.0 5 PMID:20202940;PMID:22634004;PMID:24502619;PMID:8043600 -2.1.1.100 * trypanosoma brucei 28301.0 1 PMID:12141948 -2.1.1.101 * streptomyces fradiae 65000.0 2 PMID:3170601;PMID:3170602 -2.1.1.102 * streptomyces fradiae 126000.0 2 PMID:3170602 -2.1.1.103 * arabidopsis thaliana 56100.0 1 PMID:12215503 -2.1.1.103 * caenorhabditis elegans 55100.0 2 PMID:17313371 -2.1.1.103 * haemonchus contortus 55000.0 6 PMID:21914812 -2.1.1.103 * plasmodium falciparum 31000.0 1 PMID:15073329 -2.1.1.103 * plasmodium knowlesi 31000.0 1 PMID:25761669 -2.1.1.103 * plasmodium vivax 31000.0 1 PMID:25761669 -2.1.1.103 * spinacia oleracea 77000.0 3 PMID:10799484 -2.1.1.103 * triticum aestivum 65000.0 2 PMID:12011366 -2.1.1.104 * ammi majus 27000.0 1 PMID:15556611 -2.1.1.104 * arabidopsis thaliana 29000.0 1 PMID:22258746 -2.1.1.104 * camellia sinensis 28000.0 1 PMID:25644465 -2.1.1.104 * hibiscus cannabinus 27910.0 1 * -2.1.1.104 * linum usitatissimum 33000.0 2 PMID:12060306;PMID:19004632 -2.1.1.104 * medicago sativa 30000.0 1 PMID:11169195 -2.1.1.104 * nicotiana tabacum 27000.0 1 PMID:10482677 -2.1.1.104 * oryza sativa 32000.0 5 PMID:16263700;PMID:17943312 -2.1.1.104 * petroselinum crispum 50000.0 5 PMID:16667940;PMID:2499260 -2.1.1.104 * populus tremula x populus alba 28000.0 2 PMID:10889235;PMID:11027707 -2.1.1.104 * populus trichocarpa 28000.0 1 PMID:10889235;PMID:11027707 -2.1.1.104 * triticum aestivum 38600.0 1 PMID:17976886 -2.1.1.104 * vanilla planifolia 33220.0 2 PMID:21629984 -2.1.1.104 * vitis vinifera 27230.0 1 PMID:9390437 -2.1.1.106 * streptomyces laurentii 68554.0 1 PMID:23064318 -2.1.1.107 * arabidopsis thaliana 67000.0 3 PMID:9006913 -2.1.1.107 * escherichia coli 66000.0 3 PMID:2407234 -2.1.1.107 * geobacillus stearothermophilus 60000.0 6 PMID:19154787;PMID:8534969 -2.1.1.107 * hordeum vulgare 30000.0 1 PMID:24910329 -2.1.1.107 * limosilactobacillus reuteri 51000.0 1 PMID:21484341 -2.1.1.107 * methanobacterium ivanovii 58200.0 2 PMID:1856165 -2.1.1.107 * nitratidesulfovibrio vulgaris 55000.0 1 PMID:19267692 -2.1.1.107 * propionibacterium freudenreichii 27000.0 1 PMID:7883713 -2.1.1.107 * pseudomonas aeruginosa 60000.0 2 PMID:19754882 -2.1.1.107 * pseudomonas denitrificans (nom. rej.) 56000.0 3 PMID:2211520;PMID:2546914 -2.1.1.107 * thermus thermophilus 26233.0 1 PMID:15983414 -2.1.1.107 * zea mays 79000.0 3 PMID:16289918 -2.1.1.108 * daucus carota 76000.0 1 * -2.1.1.109 * aspergillus parasiticus 43000.0 2 PMID:16349476 -2.1.1.11 * arabidopsis thaliana 120000.0 3 PMID:19076298;PMID:26759408 -2.1.1.11 * cereibacter sphaeroides 25681.0 1 PMID:7925960 -2.1.1.11 * lathyrus oleraceus 32000.0 1 PMID:19076298 -2.1.1.11 * rhodobacter capsulatus 29000.0 1 PMID:17594291 -2.1.1.110 * aspergillus parasiticus 168000.0 5 PMID:3237648;PMID:8434913 -2.1.1.111 * ruta graveolens 70000.0 3 PMID:17988223 -2.1.1.113 * caldicellulosiruptor bescii 33000.0 1 PMID:22928042 -2.1.1.113 * moraxella bovis 32111.0 2 PMID:19332813 -2.1.1.113 * moraxella cuniculi 32676.0 2 PMID:19332813 -2.1.1.113 * proteus vulgaris 36847.0 1 PMID:9288926 -2.1.1.113 * pyrococcus sp. gi-h 50355.0 2 PMID:18718929 -2.1.1.113 * xanthomonas campestris 337000.0 2 PMID:17488332 -2.1.1.114 * homo sapiens 40998.0 1 PMID:10777520 -2.1.1.115 * berberis koetineana 78000.0 2 * -2.1.1.115 * berberis vulgaris 68000.0 1 * -2.1.1.116 * berberis koetineana 51000.0 2 * -2.1.1.116 * papaver somniferum 75000.0 4 PMID:16034588;PMID:16813579 -2.1.1.117 * berberis wilsoniae 63000.0 1 PMID:24253642 -2.1.1.117 * coptis japonica 140000.0 3 PMID:7719631 -2.1.1.118 * berberis aggregata 52000.0 1 * -2.1.1.118 * berberis wilsoniae 52000.0 1 * -2.1.1.119 * eschscholzia californica 49000.0 1 * -2.1.1.12 * hordeum vulgare 115000.0 1 PMID:9765528 -2.1.1.12 * saccharomyces cerevisiae 28000.0 1 PMID:19160456 -2.1.1.12 * wollastonia biflora 450000.0 2 PMID:7673218 -2.1.1.122 * corydalis vaginans 72000.0 1 * -2.1.1.122 * eschscholzia californica 78000.0 1 * -2.1.1.122 * papaver somniferum 48000.0 1 PMID:17389594 -2.1.1.122 * sanguinaria canadensis 70000.0 2 PMID:12232209 -2.1.1.123 * euglena gracilis 28000.0 1 PMID:2981218 -2.1.1.127 * arabidopsis thaliana 54600.0 1 PMID:22547063 -2.1.1.127 * lathyrus oleraceus 60000.0 2 PMID:22547063;PMID:8527940 -2.1.1.127 * nicotiana sp. 56000.0 1 PMID:8980518 -2.1.1.128 * argemone platyceras 47000.0 1 PMID:17405035 -2.1.1.128 * coptis japonica 95000.0 2 PMID:7925429 -2.1.1.128 * eschscholzia californica 40000.0 1 PMID:17189286 -2.1.1.128 * papaver somniferum 38500.0 1 PMID:16813579 -2.1.1.128 * thalictrum flavum subsp. glaucum 85000.0 1 PMID:27232113 -2.1.1.129 * mesembryanthemum crystallinum 40250.0 2 PMID:1600940 -2.1.1.129 * vigna umbellata 106200.0 2 * -2.1.1.13 * candida albicans 112000.0 2 PMID:19324024 -2.1.1.13 * escherichia coli 200000.0 8 PMID:2853966;PMID:4154078;PMID:4946148;PMID:7004868 -2.1.1.13 * homo sapiens 160000.0 7 PMID:17288554;PMID:4055752 -2.1.1.13 * phaseolus vulgaris 40000.0 1 PMID:18397 -2.1.1.13 * rattus norvegicus 140000.0 1 PMID:10585432 -2.1.1.13 * sus scrofa 155000.0 2 PMID:7961628 -2.1.1.130 * pseudomonas denitrificans (nom. rej.) 53000.0 4 PMID:1731915;PMID:2172210;PMID:7606163 -2.1.1.131 * propionibacterium freudenreichii 91400.0 1 PMID:12055304 -2.1.1.131 * pseudomonas denitrificans (nom. rej.) 27104.0 2 PMID:2211521;PMID:8226690 -2.1.1.132 * methanothermobacter thermautotrophicus 81000.0 2 PMID:12429089 -2.1.1.132 * pseudomonas denitrificans (nom. rej.) 320000.0 4 PMID:1732195;PMID:7606163 -2.1.1.133 * pseudomonas denitrificans (nom. rej.) 31000.0 2 PMID:7606163;PMID:8226690 -2.1.1.136 * trichoderma longibrachiatum 112000.0 4 PMID:12957890;PMID:20144725 -2.1.1.137 * aquipseudomonas alcaligenes 38000.0 1 PMID:25681184 -2.1.1.137 * clostridium sp. 29060.0 1 PMID:25790486 -2.1.1.137 * cricetinae 46000.0 1 PMID:9853005 -2.1.1.137 * cyanidioschyzon sp. 44980.0 1 PMID:22712827 -2.1.1.137 * danio rerio 80000.0 1 PMID:22575231 -2.1.1.137 * homo sapiens 41700.0 2 PMID:22005461;PMID:23123458 -2.1.1.137 * oryctolagus cuniculus 60000.0 1 PMID:8605285 -2.1.1.137 * rattus norvegicus 42000.0 1 PMID:17202581 -2.1.1.137 * tetrahymena pyriformis 35400.0 2 PMID:24561426 -2.1.1.137 * thermus thermophilus 64500.0 1 PMID:34872358 -2.1.1.14 * catharanthus roseus 85000.0 2 PMID:11030427;PMID:7601135 -2.1.1.14 * escherichia coli 84000.0 2 PMID:4904482 -2.1.1.14 * saccharomyces cerevisiae 75000.0 1 * -2.1.1.14 * streptococcus mutans 80000.0 1 PMID:17012790 -2.1.1.140 * coptis japonica 160000.0 3 PMID:11314949 -2.1.1.140 * escherichia coli 44000.0 1 PMID:18639640 -2.1.1.140 * tinospora cordifolia 87000.0 2 * -2.1.1.141 * brassica rapa subsp. oleifera 44000.0 1 * -2.1.1.142 * arabidopsis thaliana 160000.0 2 PMID:14622971;PMID:19818974 -2.1.1.142 * glycine max 161000.0 7 PMID:12807886;PMID:14622971;PMID:18590960;PMID:19818974 -2.1.1.142 * gossypium hirsutum 40000.0 1 PMID:18571124 -2.1.1.142 * paracoccidioides brasiliensis 42502.0 1 PMID:20624480 -2.1.1.142 * prototheca wickerhamii 154000.0 1 PMID:10882005 -2.1.1.143 * glycine max 160000.0 4 PMID:19818974 -2.1.1.146 * clarkia breweri 88000.0 2 PMID:11884690;PMID:9439593 -2.1.1.146 * ocimum basilicum 81000.0 2 PMID:11884690;PMID:9439593 -2.1.1.146 * ocimum tenuiflorum 22490.0 1 PMID:24420851 -2.1.1.147 * corydalis cava 56000.0 1 * -2.1.1.148 * campylobacter jejuni 23800.0 1 PMID:12423760 -2.1.1.148 * helicobacter pylori 111000.0 6 PMID:12029065;PMID:21633987 -2.1.1.148 * mycobacterium tuberculosis 104000.0 1 PMID:18493582 -2.1.1.148 * paramecium bursaria chlorella virus-1 26000.0 1 PMID:15471872 -2.1.1.148 * pyrococcus furiosus 29000.0 1 PMID:16176183 -2.1.1.150 * medicago sativa 41000.0 3 PMID:16667295;PMID:9484461 -2.1.1.151 * chlorobaculum tepidum 56000.0 2 PMID:17229157 -2.1.1.151 * methanothermobacter thermautotrophicus 51000.0 2 PMID:17567575 -2.1.1.151 * salmonella enterica subsp. enterica serovar typhimurium 29000.0 1 PMID:1451790 -2.1.1.152 * pseudomonas denitrificans (nom. rej.) 31000.0 3 PMID:7606163;PMID:8226690 -2.1.1.153 * avena sativa 52000.0 1 PMID:6705789 -2.1.1.154 * medicago sativa 57000.0 2 PMID:1731632 -2.1.1.155 * dianthus caryophyllus 45000.0 1 PMID:12899699 -2.1.1.156 * aphanothece halophytica 33000.0 5 PMID:12466265 -2.1.1.156 * halorhodospira halochloris 42000.0 4 PMID:10896953;PMID:11319079 -2.1.1.156 * methanohalophilus portucalensis 56000.0 4 PMID:21949863;PMID:28036340 -2.1.1.156 * myxococcus xanthus 29500.0 1 PMID:20023011 -2.1.1.157 * actinopolyspora halophila 32000.0 1 PMID:10896953 -2.1.1.157 * aphanothece halophytica 31000.0 2 PMID:12466265 -2.1.1.157 * galdieria sulphuraria 67700.0 2 PMID:18623062 -2.1.1.157 * halorhodospira halochloris 36000.0 3 PMID:11319079 -2.1.1.157 * methanohalophilus portucalensis 38000.0 3 PMID:19693490;PMID:21949863 -2.1.1.157 * myxococcus xanthus 27900.0 1 PMID:20023011 -2.1.1.158 * coffea arabica 69000.0 5 PMID:12746542;PMID:9237402 -2.1.1.158 * coffea canephora 80000.0 2 PMID:17401201 -2.1.1.159 * camellia granthamiana 41000.0 2 PMID:19018565 -2.1.1.159 * camellia japonica 41000.0 1 PMID:19018565 -2.1.1.159 * camellia kissii 41000.0 1 PMID:19018565 -2.1.1.159 * camellia lutchuensis 41000.0 1 PMID:19018565 -2.1.1.159 * camellia petelotii 39000.0 1 PMID:19018565 -2.1.1.159 * camellia sinensis 61000.0 4 PMID:10364410;PMID:25133732 -2.1.1.159 * coffea arabica 74000.0 3 PMID:12746542;PMID:9237402 -2.1.1.159 * coffea canephora 80000.0 2 PMID:17401201 -2.1.1.159 * paullinia cupana 40100.0 1 PMID:24856135 -2.1.1.160 * camellia sinensis 61000.0 4 PMID:10364410;PMID:25133732 -2.1.1.160 * coffea arabica 81000.0 4 PMID:12746542;PMID:9237402 -2.1.1.160 * coffea canephora 80000.0 2 PMID:17401201 -2.1.1.161 * aphanothece halophytica 31210.0 3 PMID:12466265 -2.1.1.161 * parasynechococcus marenigrum wh 8102 36000.0 3 PMID:17019606 -2.1.1.162 * methanohalophilus portucalensis 240000.0 2 PMID:17098399 -2.1.1.162 * thalassiosira pseudonana 67000.0 1 PMID:29626705 -2.1.1.164 * lentzea aerocolonigenes 32000.0 2 PMID:16575939 -2.1.1.165 * arabidopsis thaliana 53500.0 3 * -2.1.1.165 * batis maritima 25761.0 3 PMID:9789006 -2.1.1.165 * brassica oleracea 29500.0 2 PMID:7721844 -2.1.1.165 * endocladia muricata 25000.0 1 PMID:2371563 -2.1.1.165 * pavlova pinguis 29000.0 1 PMID:11791711 -2.1.1.165 * raphanus sativus 29000.0 2 PMID:19723322 -2.1.1.166 * homo sapiens 24700.0 1 PMID:11827451 -2.1.1.167 * saccharomyces cerevisiae 96500.0 1 PMID:10648622 -2.1.1.169 * triticum aestivum 42616.0 3 PMID:18397325;PMID:19211254 -2.1.1.17 * homo sapiens 22000.0 2 PMID:12431977;PMID:21958070 -2.1.1.17 * rattus norvegicus 200000.0 5 PMID:1495417;PMID:3680298;PMID:3800912 -2.1.1.17 * zymomonas mobilis 120000.0 2 * -2.1.1.170 * escherichia coli 23842.0 2 PMID:12001236 -2.1.1.172 * escherichia coli 37600.0 2 PMID:9873033 -2.1.1.173 * escherichia coli 82000.0 4 PMID:10715006;PMID:17010378;PMID:21045301 -2.1.1.174 * escherichia coli 71000.0 1 PMID:17010380 -2.1.1.175 * hordeum vulgare 38700.0 1 * -2.1.1.175 * oryza sativa 31100.0 2 PMID:17943312 -2.1.1.175 * zea mays 39600.0 1 * -2.1.1.176 * escherichia coli 47140.0 2 PMID:10194318 -2.1.1.177 * escherichia coli 36800.0 1 PMID:17169371 -2.1.1.178 * escherichia coli 54000.0 1 PMID:16678201 -2.1.1.179 * escherichia coli 31500.0 3 PMID:26552988 -2.1.1.179 * micromonospora zionensis 32400.0 2 PMID:1447159;PMID:26552988 -2.1.1.180 * candidatus arthromitus sp. sfb-mouse 30000.0 1 PMID:24963996 -2.1.1.180 * catenulispora acidiphila 30000.0 2 PMID:24963996;PMID:26609134 -2.1.1.180 * thermomonospora curvata 30000.0 1 PMID:24963996 -2.1.1.180 * uncultured bacterium 30000.0 1 PMID:24963996 -2.1.1.181 * escherichia coli 34000.0 1 PMID:18021804 -2.1.1.182 * escherichia coli 30400.0 4 PMID:19223326;PMID:383712;PMID:3905517;PMID:7005624 -2.1.1.183 * kluyveromyces lactis 36300.0 1 PMID:9219342 -2.1.1.183 * saccharomyces cerevisiae 35927.0 1 PMID:8064863 -2.1.1.185 * escherichia coli 60000.0 2 PMID:12377117 -2.1.1.187 * escherichia coli 31500.0 1 PMID:14999102 -2.1.1.188 * streptococcus pneumoniae 32000.0 2 PMID:23716046;PMID:26365244 -2.1.1.19 * pseudomonas sp. 100000.0 1 PMID:6023571 -2.1.1.191 * escherichia coli 46500.0 1 PMID:18786544 -2.1.1.192 * escherichia coli k-12 43000.0 1 PMID:20184321 -2.1.1.192 * mammaliicoccus sciuri 41088.0 2 PMID:23861844 -2.1.1.193 * escherichia coli 50000.0 2 PMID:16431987;PMID:17872509 -2.1.1.197 * escherichia coli 28322.0 1 PMID:3058702 -2.1.1.198 * escherichia coli 31000.0 1 PMID:25195904 -2.1.1.2 * acomys cahirinus 31000.0 1 PMID:19570237 -2.1.1.2 * homo sapiens 60000.0 1 PMID:16899382 -2.1.1.2 * mus musculus 25000.0 1 PMID:8312439 -2.1.1.2 * rattus norvegicus 26000.0 3 PMID:3277179;PMID:6639053 -2.1.1.2 * sus scrofa 31500.0 2 PMID:500623 -2.1.1.20 * danio rerio 130000.0 2 PMID:18804700;PMID:19483083 -2.1.1.20 * homo sapiens 130000.0 2 PMID:12699692;PMID:15181470;PMID:15340920;PMID:18501206;PMID:18804700;PMID:19483083 -2.1.1.20 * mus musculus 130000.0 4 PMID:12699692;PMID:15181470;PMID:15340920;PMID:18501206;PMID:18804700;PMID:19483083 -2.1.1.20 * oryctolagus cuniculus 130000.0 3 PMID:12699692;PMID:15181470;PMID:15340920;PMID:18501206;PMID:18804700;PMID:19483083;PMID:4692843 -2.1.1.20 * rattus norvegicus 135000.0 10 PMID:12699692;PMID:1332963;PMID:15181470;PMID:15340920;PMID:16522797;PMID:18501206;PMID:18804700;PMID:19483083;PMID:6801046;PMID:9655336 -2.1.1.20 * sus scrofa 130000.0 4 PMID:18804700;PMID:19483083 -2.1.1.200 * escherichia coli 58000.0 3 PMID:16848900 -2.1.1.201 * brassica oleracea 32200.0 1 PMID:19656903 -2.1.1.201 * saccharomyces cerevisiae 34685.0 1 PMID:9083049 -2.1.1.202 * saccharomyces cerevisiae 82200.0 3 PMID:10445884 -2.1.1.203 * homo sapiens 86471.0 1 PMID:17071714 -2.1.1.206 * pyrococcus abyssi 22262.0 2 PMID:15987815 -2.1.1.207 * escherichia coli 36000.0 4 PMID:20855540;PMID:22386868;PMID:23804755 -2.1.1.208 * streptomyces viridochromogenes 67000.0 3 PMID:15581897 -2.1.1.21 * pseudomonas sp. 390000.0 2 PMID:3911004 -2.1.1.210 * rhodobacter capsulatus 43000.0 1 PMID:12770713 -2.1.1.213 * pyrococcus abyssi 39000.0 1 PMID:15210688 -2.1.1.214 * saccharomyces cerevisiae 66322.0 1 PMID:27986851 -2.1.1.216 * caenorhabditis elegans 59000.0 2 PMID:10048958 -2.1.1.216 * pyrococcus furiosus 49000.0 3 PMID:10438627;PMID:9685492 -2.1.1.216 * saccharomyces cerevisiae 64050.0 1 PMID:9801306 -2.1.1.218 * sulfolobus acidocaldarius 38000.0 2 PMID:26673726 -2.1.1.219 * pyrococcus abyssi 30000.0 1 PMID:14739239 -2.1.1.22 * gallus gallus 45000.0 3 PMID:23705015 -2.1.1.22 * oryctolagus cuniculus 85000.0 1 PMID:1446680 -2.1.1.220 * aquifex aeolicus 29000.0 2 PMID:24894648 -2.1.1.220 * mycobacterium tuberculosis 115000.0 2 PMID:14960715 -2.1.1.220 * thermus thermophilus 150000.0 2 PMID:12682365 -2.1.1.222 * escherichia coli 26600.0 1 PMID:21636923 -2.1.1.222 * homo sapiens 40998.0 1 PMID:10777520 -2.1.1.224 * escherichia coli 37000.0 1 PMID:20184321 -2.1.1.224 * mammaliicoccus sciuri 41088.0 2 PMID:23861844 -2.1.1.228 * escherichia coli 64000.0 3 PMID:14583191;PMID:15248782 -2.1.1.228 * homo sapiens 60500.0 1 PMID:15248782 -2.1.1.228 * methanocaldococcus jannaschii 42000.0 1 PMID:15165845 -2.1.1.228 * streptococcus pneumoniae 69000.0 3 PMID:15060037 -2.1.1.229 * escherichia coli 55600.0 1 PMID:23695253 -2.1.1.230 * streptomyces azureus 38000.0 1 * -2.1.1.231 * dianthus caryophyllus 45000.0 1 PMID:12899699 -2.1.1.231 * glycine max 40000.0 1 PMID:16328980 -2.1.1.232 * oryza sativa 41000.0 2 PMID:10814825 -2.1.1.233 * homo sapiens 38305.0 2 PMID:10600115;PMID:23840384;PMID:25839665 -2.1.1.233 * mus musculus 38000.0 1 PMID:10600115;PMID:23840384;PMID:25839665 -2.1.1.233 * sus scrofa 40000.0 1 PMID:10600115 -2.1.1.234 * streptomyces venezuelae 47400.0 3 PMID:10941048;PMID:12119032 -2.1.1.235 * streptomyces fradiae 55200.0 4 PMID:12119032;PMID:9031628 -2.1.1.236 * streptomyces ravidus 31060.0 1 PMID:21264378 -2.1.1.237 * micromonospora griseorubida 28600.0 1 PMID:19415708 -2.1.1.238 * micromonospora griseorubida 44800.0 1 PMID:19415708 -2.1.1.239 * streptomyces antibioticus 87000.0 2 PMID:11514520 -2.1.1.240 * sorghum bicolor 42500.0 1 PMID:25715927 -2.1.1.240 * vitis riparia 41700.0 1 PMID:25715927 -2.1.1.240 * vitis vinifera 52000.0 1 * -2.1.1.241 * zea mays 40000.0 1 PMID:18192444 -2.1.1.242 * escherichia coli 29000.0 1 PMID:22079366 -2.1.1.244 * homo sapiens 52000.0 2 PMID:30151928 -2.1.1.246 * methanosarcina barkeri 50000.0 3 PMID:10785368;PMID:8702528 -2.1.1.247 * methanosarcina barkeri 52900.0 2 PMID:9006042 -2.1.1.248 * methanosarcina barkeri 170000.0 4 PMID:15450490;PMID:16096277;PMID:9195968 -2.1.1.249 * methanosarcina barkeri 230000.0 10 PMID:10762254;PMID:10852929;PMID:15450490;PMID:17015666;PMID:9654067 -2.1.1.25 * phanerodontia chrysosporium 52000.0 1 PMID:16348886 -2.1.1.250 * methanosarcina barkeri 50000.0 1 PMID:15450490 -2.1.1.251 * methanosarcina barkeri 480000.0 4 PMID:11073950;PMID:11985589;PMID:8932317;PMID:9371433 -2.1.1.252 * methanosarcina barkeri 50000.0 1 PMID:9732435 -2.1.1.253 * methanosarcina barkeri 40000.0 1 PMID:9732435 -2.1.1.255 * streptomyces coelicolor 49955.0 2 PMID:18563898 -2.1.1.258 * clostridioides difficile 31000.0 2 PMID:21324365 -2.1.1.258 * neomoorella thermoacetica 58900.0 6 PMID:10997901;PMID:7928975 -2.1.1.259 * lathyrus oleraceus 51700.0 1 PMID:17635932 -2.1.1.260 * saccharomyces cerevisiae 32000.0 2 PMID:11935223;PMID:20972225 -2.1.1.261 * aspergillus fumigatus 75000.0 4 PMID:18678866 -2.1.1.265 * escherichia coli 26256.0 1 PMID:11053398 -2.1.1.267 * catharanthus roseus 39145.0 2 PMID:12482447 -2.1.1.267 * citrus depressa 88000.0 1 PMID:27549218 -2.1.1.267 * oryza sativa 32000.0 4 PMID:17943312 -2.1.1.267 * solanum lycopersicum 26300.0 1 PMID:25227758 -2.1.1.268 * homo sapiens 48500.0 1 PMID:34268557 -2.1.1.268 * saccharomyces cerevisiae 71500.0 2 PMID:21518805 -2.1.1.269 * candidatus pelagibacter communis 68000.0 3 PMID:18849431 -2.1.1.269 * ruegeria pomeroyi 68000.0 2 PMID:18849431 -2.1.1.270 * medicago sativa 41000.0 1 PMID:9484461 -2.1.1.271 * priestia megaterium 62000.0 4 PMID:9660189 -2.1.1.272 * priestia megaterium 65000.0 1 PMID:23155054 -2.1.1.273 * antirrhinum majus 107000.0 5 PMID:10852939;PMID:11051108;PMID:12361714 -2.1.1.273 * arabidopsis lyrata 91000.0 4 PMID:14617060 -2.1.1.273 * arabidopsis thaliana 91000.0 4 PMID:14617060 -2.1.1.273 * clarkia breweri 49000.0 1 PMID:10852939;PMID:12361714 -2.1.1.273 * lilium hybrid cultivar 41050.0 1 PMID:26600510 -2.1.1.274 * antirrhinum majus 107000.0 2 PMID:12361714 -2.1.1.274 * arabidopsis lyrata 91000.0 4 PMID:14617060 -2.1.1.274 * arabidopsis thaliana 91000.0 4 PMID:14617060 -2.1.1.274 * clarkia breweri 74500.0 4 PMID:10375393;PMID:12897246 -2.1.1.274 * lilium hybrid cultivar 41050.0 1 PMID:26600510 -2.1.1.275 * arabidopsis thaliana 41500.0 2 PMID:17220201 -2.1.1.276 * arabidopsis thaliana 43300.0 1 PMID:17220201 -2.1.1.278 * oryza sativa japonica group 43800.0 1 PMID:18162595 -2.1.1.278 * populus trichocarpa 40000.0 1 PMID:17499822 -2.1.1.279 * anethum foeniculum 80000.0 1 * -2.1.1.28 * bos taurus 38000.0 2 PMID:5412063;PMID:6847678 -2.1.1.28 * homo sapiens 60550.0 3 PMID:15893506 -2.1.1.28 * oryctolagus cuniculus 40000.0 3 PMID:4414012;PMID:623485 -2.1.1.280 * astragalus bisulcatus 38000.0 4 PMID:10026151;PMID:8706715 -2.1.1.280 * astragalus chrysochlorus 40000.0 2 * -2.1.1.280 * brassica oleracea 37900.0 1 PMID:15863700 -2.1.1.280 * camellia sinensis 58900.0 2 * -2.1.1.280 * escherichia coli 35000.0 4 PMID:10026151 -2.1.1.281 * streptomyces hygroscopicus 70200.0 2 PMID:24914966 -2.1.1.283 * aspergillus terreus 365800.0 3 PMID:1444712;PMID:35475366 -2.1.1.284 * streptomyces niveus 26500.0 1 PMID:16274243 -2.1.1.285 * streptomyces niveus 66000.0 3 PMID:17329822;PMID:19857499 -2.1.1.288 * streptomyces sp. 48000.0 3 PMID:7836284 -2.1.1.290 * saccharomyces cerevisiae 80022.0 2 PMID:19287006 -2.1.1.291 * papaver somniferum 85000.0 3 PMID:14675446 -2.1.1.292 * streptomyces sp. 166000.0 3 PMID:7836284 -2.1.1.293 * aspergillus fumigatus 64000.0 1 PMID:23649274 -2.1.1.294 * escherichia coli 81731.0 2 PMID:15184370;PMID:21990359 -2.1.1.296 * trypanosoma brucei 57000.0 2 PMID:16301606;PMID:16516986 -2.1.1.298 * azospirillum brasilense 39000.0 1 PMID:24573606 -2.1.1.299 * homo sapiens 52600.0 2 PMID:30151928 -2.1.1.303 * streptomyces carzinostaticus 39500.0 1 PMID:18387946 -2.1.1.304 * streptomyces lavendulae 42000.0 2 PMID:22187429 -2.1.1.305 * streptomyces olivaceus 41180.0 2 PMID:11376004;PMID:18310024 -2.1.1.306 * streptomyces olivaceus 42836.0 2 PMID:11376004;PMID:18310024 -2.1.1.307 * streptomyces olivaceus 29044.0 2 PMID:11376004;PMID:18310024 -2.1.1.308 * streptomyces wedmorensis 60400.0 2 PMID:24370735;PMID:7500951 -2.1.1.315 * amycolatopsis mediterranei 100000.0 2 PMID:12623077 -2.1.1.318 * saccharomyces cerevisiae 14000.0 1 PMID:24412193 -2.1.1.319 * homo sapiens 176000.0 2 PMID:11724789;PMID:39022984 -2.1.1.319 * mus musculus 50728.0 1 PMID:27879050 -2.1.1.319 * rattus norvegicus 64000.0 3 PMID:9642256 -2.1.1.320 * homo sapiens 240000.0 6 PMID:11152681 -2.1.1.321 * homo sapiens 78000.0 1 PMID:22241471 -2.1.1.321 * mus musculus 81200.0 2 PMID:24247247 -2.1.1.324 * saccharopolyspora spinosa 61200.0 3 PMID:18345667 -2.1.1.325 * aedes aegypti 32000.0 1 PMID:11520690;PMID:18549957;PMID:24657668 -2.1.1.325 * apis mellifera 33000.0 1 PMID:23874662 -2.1.1.325 * bombyx mori 69000.0 3 PMID:14530389;PMID:34562453;PMID:36341863 -2.1.1.325 * diaphorina citri 31000.0 1 PMID:25893162 -2.1.1.325 * drosophila melanogaster 32000.0 1 PMID:11520690;PMID:18549957;PMID:24657668 -2.1.1.325 * homarus americanus 38000.0 1 PMID:15262283 -2.1.1.325 * metapenaeus ensis 35000.0 2 PMID:11520690;PMID:12135499;PMID:18549957;PMID:24657668 -2.1.1.325 * palaemon carinicauda 31570.0 1 PMID:24136172 -2.1.1.325 * penaeus chinensis 31970.0 1 * -2.1.1.326 * shewanella denitrificans 64800.0 1 PMID:25224746 -2.1.1.327 * pseudomonas aeruginosa 70000.0 3 PMID:16946471;PMID:17253782 -2.1.1.33 * escherichia coli 300000.0 3 PMID:18678947;PMID:794833 -2.1.1.33 * saccharomyces cerevisiae 50000.0 2 PMID:18164779 -2.1.1.33 * salmonella enterica subsp. enterica serovar typhimurium 25000.0 1 PMID:6787407 -2.1.1.333 * chlorobaculum tepidum 40000.0 1 PMID:15792807 -2.1.1.336 * lycoris aurea 26980.0 1 PMID:29966257 -2.1.1.336 * narcissus aff. pseudonarcissus mk-2014 29000.0 2 PMID:25061748 -2.1.1.336 * narcissus papyraceus 72000.0 1 PMID:39122011 -2.1.1.337 * papaver somniferum 45000.0 2 PMID:27634038 -2.1.1.338 * humulus lupulus 76000.0 2 PMID:18223037 -2.1.1.339 * humulus lupulus 64000.0 1 PMID:18223037 -2.1.1.34 * aquifex aeolicus 54000.0 1 PMID:16511140 -2.1.1.34 * thermus thermophilus 21000.0 3 PMID:7085632 -2.1.1.340 * hordeum vulgare 45000.0 2 PMID:16664431 -2.1.1.340 * hordeum vulgare subsp. vulgare 43000.0 1 PMID:21074448 -2.1.1.341 * sphingobium sp. 104000.0 2 PMID:28429420 -2.1.1.341 * sphingomonas paucimobilis 60000.0 2 PMID:15090517;PMID:9501423 -2.1.1.343 * streptomyces davaonensis 77000.0 4 PMID:21911488;PMID:26913589 -2.1.1.35 * escherichia coli 62000.0 12 PMID:17459887;PMID:2461858;PMID:3327525;PMID:6997293;PMID:8054847;PMID:8419334 -2.1.1.35 * salmonella enterica subsp. enterica serovar typhimurium 65000.0 1 PMID:6787407 -2.1.1.354 * camellia sinensis 118250.0 1 PMID:34064673 -2.1.1.354 * drosophila melanogaster 670000.0 2 PMID:21694722 -2.1.1.354 * homo sapiens 450000.0 1 PMID:16253997 -2.1.1.355 * drosophila melanogaster 180000.0 1 PMID:22476432 -2.1.1.355 * mus musculus 70000.0 2 PMID:19646955 -2.1.1.360 * drosophila melanogaster 171000.0 1 PMID:15371351 -2.1.1.360 * mus musculus 170000.0 1 PMID:16236820 -2.1.1.361 * homo sapiens 150000.0 3 PMID:12086618;PMID:12121615;PMID:22583696 -2.1.1.362 * drosophila elegans 45000.0 1 PMID:12121615 -2.1.1.362 * homo sapiens 52000.0 2 PMID:12121615;PMID:19486527 -2.1.1.366 * homo sapiens 180000.0 1 PMID:14536086 -2.1.1.37 * bos taurus 130000.0 1 PMID:6884360 -2.1.1.37 * chaetopterus variopedatus 200000.0 2 PMID:10544268 -2.1.1.37 * chlamydomonas reinhardtii 150000.0 1 PMID:15514055 -2.1.1.37 * geobacillus stearothermophilus 66000.0 2 PMID:10369689 -2.1.1.37 * homo sapiens 135000.0 2 PMID:1187340;PMID:6409149 -2.1.1.37 * microcystis aeruginosa 47400.0 1 PMID:34634480 -2.1.1.37 * moraxella sp. 54000.0 2 PMID:1579450 -2.1.1.37 * mus musculus 240000.0 7 PMID:10790376;PMID:12071696;PMID:131936;PMID:18048024;PMID:22972351;PMID:7629184 -2.1.1.37 * oryza sativa 170000.0 3 PMID:19401269;PMID:2049093 -2.1.1.37 * patiria pectinifera 190000.0 1 PMID:12071696;PMID:22972351;PMID:7629184 -2.1.1.37 * rattus norvegicus 115000.0 1 PMID:673848 -2.1.1.37 * triticum aestivum 55000.0 1 PMID:3622512 -2.1.1.373 * thalassiosira pseudonana 40000.0 1 PMID:29574051 -2.1.1.38 * streptomyces alboniger 68000.0 1 PMID:5773275 -2.1.1.385 * neomoorella thermoacetica 48000.0 1 PMID:11344134 -2.1.1.386 * acetivibrio thermocellus 120000.0 1 PMID:20007328 -2.1.1.39 * catharanthus roseus 30000.0 1 * -2.1.1.39 * vinca minor 27000.0 1 PMID:1002125 -2.1.1.395 * carapichea ipecacuanha 38700.0 1 PMID:20061395 -2.1.1.396 * carapichea ipecacuanha 38700.0 1 PMID:20061395 -2.1.1.4 * bos taurus 78000.0 4 PMID:29942;PMID:3298987;PMID:3783420;PMID:5010087;PMID:6827276 -2.1.1.4 * gallus gallus 39000.0 1 PMID:6827276 -2.1.1.4 * homo sapiens 42000.0 1 PMID:8574683 -2.1.1.4 * rattus norvegicus 38000.0 1 PMID:29942;PMID:3783420 -2.1.1.40 * lathyrus oleraceus 42000.0 2 PMID:1002125;PMID:5362620 -2.1.1.402 * asterias rubens 62000.0 2 PMID:9490063 -2.1.1.41 * candida albicans 178000.0 3 PMID:20946868;PMID:2692713 -2.1.1.41 * leishmania infantum 39800.0 1 PMID:17804125 -2.1.1.41 * paracoccidioides brasiliensis 42500.0 1 PMID:20624480 -2.1.1.41 * saccharomyces cerevisiae 172000.0 1 PMID:9606964 -2.1.1.41 * trypanosoma brucei 160000.0 2 PMID:16414960 -2.1.1.42 * arabidopsis thaliana 45000.0 1 PMID:10700397 -2.1.1.42 * citrus depressa 88000.0 1 PMID:27549218 -2.1.1.42 * glycine max 64000.0 1 PMID:16777424 -2.1.1.42 * hordeum vulgare 38700.0 1 * -2.1.1.42 * oryza sativa 32000.0 4 PMID:17943312 -2.1.1.42 * petroselinum crispum 48000.0 1 * -2.1.1.42 * zea mays 39600.0 1 * -2.1.1.44 * neurospora crassa 300000.0 1 PMID:5484456 -2.1.1.45 * angiostrongylus cantonensis 66000.0 2 PMID:34155;PMID:8001663;PMID:8807052 -2.1.1.45 * babesia gibsoni 58800.0 2 PMID:18794380 -2.1.1.45 * bos taurus 70000.0 2 PMID:10841779;PMID:235997;PMID:3567221;PMID:6990200;PMID:7238733;PMID:8679542;PMID:99641 -2.1.1.45 * corynebacterium glutamicum 29400.0 2 PMID:20595007 -2.1.1.45 * crithidia fasciculata 175000.0 2 PMID:14696;PMID:6392123 -2.1.1.45 * cryptococcus neoformans 35840.0 2 PMID:7821787 -2.1.1.45 * daucus carota 185000.0 1 * -2.1.1.45 * escherichia coli 70000.0 8 PMID:2201779;PMID:42538;PMID:6990200;PMID:8001663;PMID:8807052;PMID:9100016;PMID:99641 -2.1.1.45 * escherichia phage t2 64400.0 3 PMID:4208776;PMID:6296121 -2.1.1.45 * gallus gallus 58000.0 1 PMID:235997;PMID:5166749;PMID:7103057 -2.1.1.45 * geobacillus virus e2 31000.0 2 PMID:18648921 -2.1.1.45 * homo sapiens 148000.0 7 PMID:10841779;PMID:12147691;PMID:17297914;PMID:235997;PMID:34155;PMID:3567221;PMID:6990200;PMID:7238733;PMID:8001663;PMID:8679542;PMID:99641 -2.1.1.45 * kitasatospora aureofaciens 77000.0 2 PMID:1605647 -2.1.1.45 * lacticaseibacillus casei 71000.0 6 PMID:10841779;PMID:235997;PMID:3567221;PMID:6990200;PMID:7238733;PMID:7556218;PMID:8679542;PMID:99641 -2.1.1.45 * leishmania major 150000.0 3 PMID:3606123;PMID:6392123 -2.1.1.45 * mus musculus 78000.0 10 PMID:10841779;PMID:235997;PMID:3567221;PMID:500657;PMID:5166749;PMID:6990200;PMID:7028756;PMID:7103057;PMID:7238733;PMID:7708505;PMID:8679542;PMID:99641 -2.1.1.45 * mycobacterium tuberculosis 104000.0 5 PMID:18493582 -2.1.1.45 * plasmodium berghei 150000.0 3 PMID:6392123 -2.1.1.45 * plasmodium falciparum 71000.0 2 PMID:8001663;PMID:8807052 -2.1.1.45 * rattus norvegicus 68000.0 2 PMID:10841779;PMID:235997;PMID:3567221;PMID:6990200;PMID:7028756;PMID:7238733;PMID:8679542;PMID:99641 -2.1.1.45 * saccharomyces cerevisiae 68000.0 3 PMID:3567221;PMID:7028756 -2.1.1.45 * streptococcus pneumoniae 70000.0 2 PMID:235997;PMID:5166749;PMID:7708505 -2.1.1.45 * tequatrovirus t4 58000.0 3 PMID:4273803;PMID:6296121 -2.1.1.45 * tequintavirus t5 55000.0 1 PMID:4273803 -2.1.1.45 * tetradesmus obliquus 100000.0 2 PMID:3606123 -2.1.1.45 * trypanosoma cruzi 200000.0 2 PMID:14696;PMID:19923744 -2.1.1.46 * cicer arietinum 110000.0 1 PMID:4452353 -2.1.1.47 * streptomyces griseus 58500.0 2 PMID:805896;PMID:809439 -2.1.1.49 * oryctolagus cuniculus 30000.0 1 PMID:3949799 -2.1.1.5 * aphanothece halophytica 350000.0 2 PMID:11391473 -2.1.1.5 * homo sapiens 270000.0 5 PMID:12071701;PMID:1370132;PMID:22775318;PMID:3657557;PMID:7174675;PMID:9681996 -2.1.1.5 * mus musculus 40300.0 1 PMID:17086380 -2.1.1.5 * rattus norvegicus 270000.0 3 PMID:1370132;PMID:19239903;PMID:3657557;PMID:7174675 -2.1.1.50 * catharanthus roseus 42020.0 1 PMID:18326827 -2.1.1.53 * anisodus acutangulus 38120.0 2 PMID:19055544 -2.1.1.53 * anisodus tanguticus 37000.0 1 PMID:16254839 -2.1.1.53 * datura stramonium 360000.0 2 * -2.1.1.53 * nicotiana tabacum 60000.0 1 * -2.1.1.53 * solanum tuberosum 38180.0 1 PMID:16088399 -2.1.1.56 * dengue virus 30000.0 1 PMID:20655081 -2.1.1.56 * encephalitozoon cuniculi 40000.0 1 PMID:15760890 -2.1.1.56 * homo sapiens 56000.0 1 PMID:956186 -2.1.1.56 * human respiratory syncytial virus a 49300.0 1 PMID:33956914 -2.1.1.56 * orthopoxvirus vaccinia 129000.0 6 PMID:1194286;PMID:1322901;PMID:2161527;PMID:659428;PMID:8195132 -2.1.1.56 * saccharomyces cerevisiae 49000.0 1 PMID:6345158 -2.1.1.56 * trypanosoma brucei 39000.0 1 PMID:16431985 -2.1.1.56 * xenopus laevis 70000.0 3 PMID:10679253 -2.1.1.57 * bluetongue virus 74000.0 1 PMID:25834778 -2.1.1.57 * dengue virus 33000.0 1 PMID:12032088 -2.1.1.57 * feline coronavirus 65000.0 2 PMID:19776234 -2.1.1.57 * human respiratory syncytial virus a 49300.0 1 PMID:33956914 -2.1.1.57 * orthopoxvirus vaccinia 38000.0 3 PMID:1313572;PMID:701281 -2.1.1.57 * severe acute respiratory syndrome-related coronavirus 35000.0 1 PMID:22022266 -2.1.1.57 * trypanosoma brucei 57000.0 2 PMID:16301606 -2.1.1.59 * neurospora crassa 120000.0 1 PMID:203592;PMID:6238220 -2.1.1.59 * saccharomyces cerevisiae 97000.0 1 PMID:220257 -2.1.1.6 * candida tropicalis 32000.0 1 PMID:160694 -2.1.1.6 * homo sapiens 32000.0 11 PMID:17418156;PMID:17588591;PMID:17880176;PMID:17894650;PMID:1932084;PMID:1993083;PMID:2037148;PMID:2089100;PMID:3973595;PMID:413582;PMID:689028 -2.1.1.6 * mus musculus 28000.0 2 PMID:19930170 -2.1.1.6 * niastella koreensis 48000.0 1 PMID:33596655 -2.1.1.6 * penaeus chinensis 30000.0 1 * -2.1.1.6 * rattus norvegicus 47500.0 15 PMID:18831714;PMID:19111934;PMID:2037148;PMID:2089100;PMID:2338148;PMID:413582;PMID:689028;PMID:7329304;PMID:762061;PMID:8027527;PMID:912603 -2.1.1.6 * streptomyces griseus 36000.0 1 PMID:11055938 -2.1.1.6 * sus scrofa 23000.0 1 PMID:2037148;PMID:2089100;PMID:413582;PMID:689028 -2.1.1.60 * arabidopsis thaliana 34500.0 1 PMID:24285794 -2.1.1.60 * homo sapiens 36000.0 1 PMID:23285036 -2.1.1.60 * mus musculus 36000.0 1 PMID:23285036 -2.1.1.60 * paramecium tetraurelia 37000.0 2 PMID:8123667 -2.1.1.60 * rattus norvegicus 65000.0 3 PMID:3102693;PMID:3700427;PMID:6685812 -2.1.1.61 * escherichia coli 79000.0 1 PMID:3298234 -2.1.1.61 * homo sapiens 47750.0 1 PMID:16513084 -2.1.1.61 * mus musculus 47240.0 1 PMID:14746906 -2.1.1.62 * homo sapiens 65000.0 1 PMID:670176 -2.1.1.62 * staphylococcus aureus 29000.0 1 PMID:6792593 -2.1.1.63 * aquifex aeolicus 23000.0 1 PMID:12892560;PMID:16777483 -2.1.1.63 * archaeoglobus fulgidus 16718.0 1 PMID:12892560 -2.1.1.63 * escherichia coli 39377.0 3 PMID:9484244;PMID:9618477 -2.1.1.63 * homo sapiens 51000.0 9 PMID:12892560;PMID:16777483;PMID:17138560;PMID:18812520;PMID:22986464;PMID:2394694;PMID:7532116;PMID:9618477 -2.1.1.63 * mus musculus 22500.0 1 PMID:7532116 -2.1.1.63 * mycobacterium tuberculosis 17844.0 1 PMID:23564173 -2.1.1.63 * pyrobaculum islandicum 15000.0 1 PMID:9618477 -2.1.1.63 * pyrococcus furiosus 22000.0 1 PMID:9618477 -2.1.1.63 * saccharolobus solfataricus 17040.0 1 PMID:22167184 -2.1.1.63 * saccharomyces cerevisiae 21000.0 1 PMID:19164530 -2.1.1.63 * sulfolobus acidocaldarius 16000.0 1 PMID:9618477 -2.1.1.63 * thermococcus litoralis 23000.0 1 PMID:9618477 -2.1.1.64 * escherichia coli 50000.0 2 PMID:21636923;PMID:769831 -2.1.1.64 * homo sapiens 40998.0 1 PMID:10777520 -2.1.1.67 * homo sapiens 36000.0 5 PMID:18602085;PMID:18605963;PMID:1981712;PMID:22274639;PMID:6838629;PMID:7603453;PMID:9539138 -2.1.1.67 * mammalia 35000.0 1 * -2.1.1.68 * arabidopsis thaliana 40000.0 1 PMID:22258746 -2.1.1.68 * conioselinum anthriscoides 43000.0 2 PMID:26254784 -2.1.1.68 * leucaena leucocephala 80000.0 3 * -2.1.1.68 * medicago sativa 103000.0 3 PMID:11169195;PMID:1898010 -2.1.1.68 * nicotiana tabacum 93000.0 1 * -2.1.1.68 * oryza sativa 42300.0 2 * -2.1.1.68 * populus tremuloides 60000.0 3 PMID:1368360;PMID:1932694 -2.1.1.68 * trigonella foenum-graecum 40000.0 1 PMID:21604170 -2.1.1.68 * triticum aestivum 40000.0 1 PMID:17976886 -2.1.1.68 * vanilla planifolia 42000.0 4 PMID:15118832;PMID:16830185 -2.1.1.69 * ammi majus 38700.0 1 PMID:15009205 -2.1.1.69 * angelica dahurica 39000.0 1 * -2.1.1.69 * petroselinum crispum 73000.0 2 * -2.1.1.69 * ruta graveolens 110000.0 1 PMID:28084 -2.1.1.7 * glycine max 90000.0 3 PMID:3364975 -2.1.1.70 * petroselinum crispum 67000.0 2 * -2.1.1.70 * ruta graveolens 850000.0 1 PMID:28084 -2.1.1.71 * homo sapiens 26000.0 2 PMID:20860552 -2.1.1.71 * saccharomyces cerevisiae 23150.0 1 PMID:9370325 -2.1.1.72 * aeromonas hydrophila 34000.0 2 PMID:16368997 -2.1.1.72 * caulobacter vibrioides 40000.0 2 PMID:11943171;PMID:21926159;PMID:26475175 -2.1.1.72 * cereibacter sphaeroides 74400.0 1 PMID:16464821 -2.1.1.72 * escherichia coli 30000.0 1 PMID:25540012 -2.1.1.72 * geobacillus stearothermophilus 31000.0 1 * -2.1.1.72 * haemophilus influenzae 38000.0 1 PMID:22102579 -2.1.1.72 * haemophilus influenzae biotype aegyptius 34000.0 1 PMID:22102579 -2.1.1.72 * helicobacter pylori 144000.0 5 PMID:20180846;PMID:21347417 -2.1.1.72 * klebsiella pneumoniae 90000.0 2 PMID:12506109 -2.1.1.72 * methylophilus methylotrophus 105100.0 1 PMID:18931376 -2.1.1.72 * neisseria gonorrhoeae 77500.0 1 PMID:19758331 -2.1.1.72 * neisseria meningitidis 33600.0 1 PMID:22102579 -2.1.1.72 * pyrococcus horikoshii 40200.0 1 PMID:21839719 -2.1.1.72 * tequatrovirus t4 30690.0 6 PMID:12937411;PMID:7782299 -2.1.1.72 * triticum aestivum 39000.0 1 PMID:11943171;PMID:26475175 -2.1.1.72 * yersinia enterocolitica 31200.0 1 PMID:16000719 -2.1.1.74 * bacillus subtilis 47900.0 2 PMID:20412857 -2.1.1.76 * chrysosplenium americanum 65000.0 2 PMID:3994393 -2.1.1.76 * citrus depressa 88000.0 1 PMID:27549218 -2.1.1.76 * oryza sativa 40066.0 1 PMID:24841874 -2.1.1.76 * serratula tinctoria 35000.0 2 PMID:15084728 -2.1.1.76 * solanum habrochaites 40000.0 1 PMID:22711283 -2.1.1.77 * arabidopsis thaliana 36000.0 12 PMID:11049748;PMID:18318686;PMID:3355545 -2.1.1.77 * bos taurus 35000.0 5 PMID:2684970;PMID:3167043;PMID:3355545 -2.1.1.77 * cicer arietinum 31000.0 2 PMID:23284083 -2.1.1.77 * cyberlindnera jadinii 25000.0 1 * -2.1.1.77 * equus sp. 26000.0 1 PMID:3355545 -2.1.1.77 * escherichia coli 35000.0 4 PMID:1860862;PMID:20857228;PMID:9784234 -2.1.1.77 * homo sapiens 28000.0 6 PMID:11049748;PMID:2684970;PMID:3167043;PMID:3355545 -2.1.1.77 * oryza sativa 26000.0 1 PMID:26438231 -2.1.1.77 * rattus norvegicus 27000.0 5 PMID:1854790;PMID:1998518;PMID:7663167 -2.1.1.77 * thermotoga maritima 36400.0 2 PMID:9784234 -2.1.1.77 * torpedo ocellata 30000.0 2 PMID:3355545 -2.1.1.77 * vibrio cholerae serotype o1 26600.0 4 PMID:23274130 -2.1.1.77 * xenopus laevis 34000.0 1 * -2.1.1.79 * escherichia coli 90000.0 2 PMID:1445840;PMID:380648 -2.1.1.79 * leishmania infantum 55000.0 1 PMID:23251490 -2.1.1.79 * oenococcus oeni 45000.0 1 PMID:26294376 -2.1.1.79 * sterculia foetida 98000.0 1 * -2.1.1.8 * bos taurus 34800.0 2 PMID:3707517 -2.1.1.8 * cavia porcellus 33000.0 2 PMID:6864213;PMID:8152327 -2.1.1.8 * homo sapiens 33000.0 1 PMID:7943261 -2.1.1.8 * mus musculus 32000.0 1 PMID:8152327 -2.1.1.8 * rattus norvegicus 36000.0 4 PMID:4016144;PMID:4059182;PMID:6415051 -2.1.1.8 * sus scrofa 32000.0 1 PMID:8152327 -2.1.1.80 * arabidopsis thaliana 73000.0 1 PMID:21062871 -2.1.1.80 * bacillus subtilis 44000.0 3 PMID:6387374;PMID:6803772;PMID:6806296 -2.1.1.80 * mammalia 25000.0 1 PMID:6387374 -2.1.1.80 * pseudomonas putida 38600.0 2 PMID:23677992 -2.1.1.80 * salmonella enterica subsp. enterica serovar typhimurium 38000.0 3 PMID:322131;PMID:3298235 -2.1.1.82 * chrysosplenium americanum 57000.0 1 PMID:3994393 -2.1.1.82 * populus sp. 60000.0 1 PMID:20680484 -2.1.1.83 * chrysosplenium americanum 57000.0 1 PMID:3994393 -2.1.1.84 * chrysosplenium americanum 57000.0 1 PMID:3994393 -2.1.1.85 * oryctolagus cuniculus 70000.0 1 PMID:1446680 -2.1.1.88 * lotus corniculatus 55000.0 1 PMID:4076180 -2.1.1.9 * brassica oleracea 30000.0 2 PMID:12369626 -2.1.1.9 * euglena gracilis 21000.0 1 * -2.1.1.9 * oryza sativa 27300.0 2 * -2.1.1.9 * phaeodactylum tricornutum 34000.0 2 PMID:21227473 -2.1.1.9 * raphanus sativus 29000.0 2 PMID:19723322 -2.1.1.9 * rattus norvegicus 28000.0 3 PMID:485170;PMID:6276653 -2.1.1.90 * methanosarcina barkeri 122000.0 7 PMID:6438059;PMID:8798395;PMID:9057830 -2.1.1.91 * pseudomonas sp. 84000.0 2 PMID:3977861 -2.1.1.94 * catharanthus roseus 40000.0 3 PMID:18053006;PMID:35947213 -2.1.1.95 * arabidopsis thaliana 37000.0 1 PMID:25051898 -2.1.1.95 * brassica oleracea 39000.0 2 * -2.1.1.95 * capsicum annuum 600000.0 4 PMID:12492478;PMID:4066669 -2.1.1.95 * chlamydomonas reinhardtii 37000.0 2 PMID:21883249 -2.1.1.95 * euglena gracilis 150000.0 1 PMID:1420294 -2.1.1.95 * lactuca sativa 33060.0 1 PMID:22194177 -2.1.1.96 * mus musculus 29460.0 3 PMID:3350800;PMID:38876259;PMID:7819283 -2.1.1.97 * streptomyces antibioticus 37000.0 2 PMID:2445729;PMID:2450873 -2.1.1.98 * aeropyrum pernix 31500.0 1 PMID:18391406 -2.1.1.98 * pyrococcus horikoshii 30000.0 2 PMID:18391406;PMID:20873788 -2.1.1.99 * catharanthus roseus 60000.0 1 * -2.1.2.1 * alcanivorax sp. 45200.0 1 * -2.1.2.1 * bacillus subtilis 25000.0 1 PMID:18483062 -2.1.2.1 * bos taurus 45000.0 1 PMID:1849406 -2.1.2.1 * danio rerio 200000.0 5 PMID:16242955;PMID:17664250 -2.1.2.1 * escherichia coli 115000.0 7 PMID:19019081;PMID:19909338;PMID:3891721 -2.1.2.1 * euglena gracilis 90000.0 4 PMID:12089472 -2.1.2.1 * geobacillus stearothermophilus 180000.0 3 PMID:12089472 -2.1.2.1 * glycine max 230000.0 2 PMID:16664855 -2.1.2.1 * homo sapiens 195000.0 3 PMID:24698160 -2.1.2.1 * hydrogenobacter thermophilus 74000.0 2 PMID:22141341 -2.1.2.1 * hyphomicrobium methylovorum 98000.0 3 PMID:12902326;PMID:3830156 -2.1.2.1 * lathyrus oleraceus 220000.0 1 PMID:3110140;PMID:3143355 -2.1.2.1 * leishmania donovani 216000.0 3 PMID:17142057 -2.1.2.1 * leishmania major 53100.0 2 PMID:16876889 -2.1.2.1 * macaca radiata 208000.0 2 PMID:6821365 -2.1.2.1 * medicago truncatula 197000.0 2 PMID:29868052 -2.1.2.1 * methanocaldococcus jannaschii 98000.0 2 PMID:12902326;PMID:3830156 -2.1.2.1 * methanosarcina barkeri 100000.0 3 PMID:15349715 -2.1.2.1 * mus musculus 215000.0 2 PMID:2373684 -2.1.2.1 * mycobacterium tuberculosis 91200.0 4 PMID:12913008 -2.1.2.1 * oryctolagus cuniculus 215000.0 4 PMID:22900314;PMID:5808700;PMID:7400147;PMID:7607226 -2.1.2.1 * ovis aries 213000.0 5 PMID:12392447;PMID:22900314;PMID:7400147;PMID:7607226;PMID:8660666 -2.1.2.1 * plasmodium falciparum 85000.0 5 PMID:19591881;PMID:19591883;PMID:21129192 -2.1.2.1 * plasmodium vivax 72400.0 2 PMID:19549189 -2.1.2.1 * pseudomonas plecoglossicida 60000.0 2 PMID:23913024 -2.1.2.1 * psychromonas ingrahamii 45050.0 1 PMID:25044250 -2.1.2.1 * rattus norvegicus 230000.0 7 PMID:3110140;PMID:3143355;PMID:6795186 -2.1.2.1 * saccharolobus solfataricus 53000.0 1 PMID:9393711 -2.1.2.1 * saccharomyces cerevisiae 200000.0 1 PMID:4591722 -2.1.2.1 * shewanella algae 45300.0 1 PMID:23632047 -2.1.2.1 * solanum tuberosum 200000.0 1 PMID:16367955 -2.1.2.1 * spinacia oleracea 209000.0 2 PMID:22900314;PMID:7400147;PMID:7607226 -2.1.2.1 * synechocystis sp. 50000.0 1 PMID:16877700 -2.1.2.1 * trichomonas vaginalis 50000.0 1 PMID:16980404 -2.1.2.1 * vigna radiata 205000.0 2 PMID:16662139 -2.1.2.10 * escherichia coli 57000.0 2 PMID:20375021 -2.1.2.10 * gallus gallus 41000.0 2 PMID:7053363 -2.1.2.10 * lathyrus oleraceus 45000.0 1 PMID:3143355 -2.1.2.10 * pyrococcus horikoshii 75000.0 2 PMID:15272174 -2.1.2.10 * rattus norvegicus 33000.0 1 PMID:4460882 -2.1.2.11 * aspergillus nidulans 340000.0 3 PMID:10503542 -2.1.2.11 * escherichia coli 285000.0 7 PMID:374973;PMID:6463;PMID:8096212 -2.1.2.11 * mycobacterium tuberculosis 120000.0 4 PMID:12515554 -2.1.2.11 * mycobacterium tuberculosis variant bovis 35000.0 2 * -2.1.2.2 * bacillus subtilis 26000.0 3 PMID:19574646;PMID:2185839 -2.1.2.2 * drosophila melanogaster 145000.0 1 PMID:2185839 -2.1.2.2 * escherichia coli 42400.0 9 PMID:10835105;PMID:11352469;PMID:1631098;PMID:2185839;PMID:8117714 -2.1.2.2 * gallus gallus 190000.0 14 PMID:3986180;PMID:4084560;PMID:6386041;PMID:666851;PMID:7354066;PMID:7417406 -2.1.2.2 * homo sapiens 112000.0 5 PMID:17198385;PMID:2925682;PMID:9143358 -2.1.2.2 * mus musculus 125000.0 5 PMID:1631098;PMID:2925682;PMID:3986180 -2.1.2.2 * oryctolagus cuniculus 215000.0 1 PMID:7354066 -2.1.2.2 * ovis aries 201000.0 1 PMID:666851 -2.1.2.2 * pseudomonas aeruginosa 31000.0 2 PMID:11390682 -2.1.2.2 * rattus norvegicus 70000.0 1 * -2.1.2.2 * saccharomyces cerevisiae 150000.0 1 PMID:666851 -2.1.2.2 * sus scrofa 218000.0 1 PMID:666851 -2.1.2.3 * candidatus liberibacter asiaticus 125000.0 1 PMID:38615986 -2.1.2.3 * escherichia coli 22000.0 1 PMID:29799386 -2.1.2.3 * homo sapiens 65630.0 6 PMID:7947835;PMID:8567683;PMID:9378707 -2.1.2.3 * staphylococcus lugdunensis 106000.0 1 PMID:29063699 -2.1.2.3 * thermotoga maritima 49700.0 1 PMID:18260100 -2.1.2.5 * gallus gallus 59100.0 1 PMID:9677386 -2.1.2.5 * rattus norvegicus 480000.0 4 PMID:7901203;PMID:9677387;PMID:9837973 -2.1.2.5 * sus scrofa 480000.0 7 PMID:10673422;PMID:7654689;PMID:7901203;PMID:9677387 -2.1.2.7 * aminobacter sp. aj110403 73000.0 1 PMID:18997407 -2.1.2.7 * ensifer sp. aj110404 80000.0 1 PMID:18997407 -2.1.2.8 * bacteriophage t6r+ 68000.0 1 PMID:14217882 -2.1.2.8 * enterobacteria phage t6 28450.0 1 PMID:3350013 -2.1.2.8 * escherichia phage t2 28450.0 1 PMID:3350013 -2.1.2.8 * tequatrovirus t4 63000.0 12 PMID:10064578;PMID:3284582;PMID:3295783;PMID:332172;PMID:3350013;PMID:6853543;PMID:7599133;PMID:7947710 -2.1.2.9 * bos taurus 40000.0 1 PMID:9832609 -2.1.2.9 * enterococcus faecalis 29900.0 1 PMID:4206871 -2.1.2.9 * escherichia coli 34000.0 6 PMID:1373194;PMID:5337045;PMID:6387369;PMID:6989606 -2.1.2.9 * euglena gracilis 38000.0 1 PMID:407934 -2.1.2.9 * triticum aestivum 45000.0 1 PMID:5544683 -2.1.3.1 * corynebacterium glutamicum 58000.0 1 PMID:17277455 -2.1.3.1 * propionibacterium freudenreichii 67000.0 6 PMID:17156879 -2.1.3.1 * propionibacterium freudenreichii subsp. shermanii 330000.0 10 PMID:1112797;PMID:1526981;PMID:17134979;PMID:18680460;PMID:40985;PMID:8251758;PMID:8344927;PMID:8346913;PMID:8399222;PMID:8425112 -2.1.3.10 * malonomonas rubra 67000.0 2 PMID:18251085 -2.1.3.12 * streptomyces niveus 79000.0 3 PMID:15157876;PMID:18997325 -2.1.3.2 * aquifex aeolicus 112800.0 3 PMID:14534296 -2.1.3.2 * azotobacter vinelandii 300000.0 1 * -2.1.3.2 * bacillus subtilis 102000.0 2 PMID:241753 -2.1.3.2 * citrobacter freundii 250000.0 2 * -2.1.3.2 * enterococcus faecalis 140000.0 4 PMID:4204271;PMID:99635 -2.1.3.2 * escherichia coli 310000.0 6 PMID:22011033;PMID:8535162 -2.1.3.2 * homo sapiens 102000.0 2 PMID:24316846 -2.1.3.2 * mesocricetus auratus 40000.0 1 PMID:6300078 -2.1.3.2 * methanocaldococcus jannaschii 129000.0 4 PMID:10748118 -2.1.3.2 * mycolicibacterium smegmatis 246000.0 3 PMID:3342242 -2.1.3.2 * neobodo saliens 35000.0 1 PMID:17475213 -2.1.3.2 * pseudomonas aeruginosa 457000.0 4 PMID:11959858;PMID:32126100 -2.1.3.2 * pseudomonas fluorescens 360000.0 2 PMID:4336369;PMID:99636 -2.1.3.2 * pseudomonas vulgaris 300000.0 2 * -2.1.3.2 * pyrococcus abyssi 301000.0 3 PMID:15943802 -2.1.3.2 * salmonella enterica subsp. enterica serovar typhimurium 300000.0 1 * -2.1.3.2 * serratia marcescens 300000.0 1 * -2.1.3.2 * sulfolobus acidocaldarius 340000.0 4 PMID:10447693 -2.1.3.2 * thermochaetoides thermophila 119000.0 1 PMID:36677714 -2.1.3.2 * thermotoga maritima 200000.0 1 PMID:9829951 -2.1.3.2 * vibrio natriegens 300000.0 1 * -2.1.3.2 * vibrio sp. 320000.0 1 * -2.1.3.2 * vigna radiata var. radiata 128000.0 6 PMID:453523;PMID:4611764;PMID:4658988 -2.1.3.3 * alnus glutinosa 200000.0 1 * -2.1.3.3 * amycolatopsis lactamdurans 57148.0 1 PMID:7557411 -2.1.3.3 * arundinaria sp. 224000.0 2 PMID:16660023 -2.1.3.3 * bacillus subtilis 260000.0 5 PMID:6409880 -2.1.3.3 * bos taurus 108000.0 2 PMID:4622303 -2.1.3.3 * canavalia lineata 109000.0 2 PMID:10808070;PMID:3131308;PMID:6418730;PMID:9346304;PMID:9640663 -2.1.3.3 * caretta caretta 112000.0 2 PMID:12108925;PMID:2930186 -2.1.3.3 * daucus carota 158000.0 1 * -2.1.3.3 * desmonostoc muscorum 75000.0 1 PMID:16659361 -2.1.3.3 * enterococcus faecalis 230000.0 4 PMID:22363663;PMID:4622303 -2.1.3.3 * escherichia coli 110000.0 5 PMID:1406593;PMID:32027716;PMID:3592910;PMID:4319;PMID:4613551;PMID:6393952;PMID:6418730;PMID:6767684;PMID:893420;PMID:9346304 -2.1.3.3 * gallus gallus 110000.0 2 PMID:10808070;PMID:1406593;PMID:3131308;PMID:32027716;PMID:3592910;PMID:6418730;PMID:6767684;PMID:893420;PMID:9346304;PMID:9640663 -2.1.3.3 * giardia duodenalis 90000.0 2 PMID:19507245 -2.1.3.3 * halobacterium salinarum 200000.0 2 PMID:7868583 -2.1.3.3 * homo sapiens 114000.0 4 PMID:11538003;PMID:1406593;PMID:20459380;PMID:25896;PMID:32027716;PMID:3592910;PMID:6418730;PMID:6767684;PMID:893420;PMID:9346304 -2.1.3.3 * lathyrus oleraceus 108200.0 3 PMID:11538003;PMID:16664120;PMID:6767684;PMID:893420 -2.1.3.3 * lathyrus sativus 56000.0 2 PMID:6895223 -2.1.3.3 * lentilactobacillus hilgardii 240000.0 4 PMID:17620711;PMID:19666033 -2.1.3.3 * mycobacterium tuberculosis 33000.0 1 PMID:18062991 -2.1.3.3 * mycobacterium tuberculosis variant bovis 110000.0 4 PMID:1406593;PMID:24568683;PMID:32027716;PMID:3592910;PMID:6418730;PMID:6767684;PMID:893420;PMID:9346304 -2.1.3.3 * mycolicibacterium smegmatis 116000.0 1 PMID:3566963 -2.1.3.3 * neisseria gonorrhoeae 110000.0 2 PMID:11538003;PMID:1406593;PMID:32027716;PMID:3592910;PMID:6418730;PMID:6767684;PMID:893420;PMID:9346304 -2.1.3.3 * neurospora crassa 115000.0 3 PMID:3159341;PMID:6370999;PMID:8135541 -2.1.3.3 * ovis aries 102000.0 2 PMID:14527149 -2.1.3.3 * phaseolus vulgaris 109000.0 2 PMID:10808070;PMID:3131308;PMID:6418730;PMID:9346304;PMID:9640663 -2.1.3.3 * pseudomonas aeruginosa 420000.0 5 PMID:10808070;PMID:3109911;PMID:3131308;PMID:4613551;PMID:6418730;PMID:8168544;PMID:9346304;PMID:9640663 -2.1.3.3 * pseudomonas syringae 110000.0 1 PMID:1406593;PMID:32027716;PMID:3592910;PMID:6418730;PMID:6767684;PMID:893420;PMID:9346304 -2.1.3.3 * pyrococcus furiosus 400000.0 1 PMID:9288930 -2.1.3.3 * rattus norvegicus 112000.0 6 PMID:4061826;PMID:489581;PMID:7356142 -2.1.3.3 * saccharomyces cerevisiae 125000.0 4 PMID:3131308;PMID:3159341;PMID:4613551;PMID:6370999;PMID:6393952;PMID:8135541 -2.1.3.3 * salmonella enterica subsp. enterica serovar typhimurium 116000.0 2 PMID:14923 -2.1.3.3 * spinacia oleracea 118000.0 2 * -2.1.3.3 * squalus acanthias 113000.0 2 PMID:12108925;PMID:2930186 -2.1.3.3 * streptomyces fradiae 87000.0 2 * -2.1.3.3 * suncus murinus 35000.0 1 * -2.1.3.3 * sus scrofa 107000.0 2 PMID:3159341;PMID:6370999;PMID:8135541 -2.1.3.3 * thermus thermophilus 110000.0 2 PMID:10808070;PMID:1406593;PMID:3131308;PMID:32027716;PMID:3592910;PMID:6418730;PMID:6767684;PMID:893420;PMID:9346304;PMID:9640663 -2.1.3.6 * cucumis sativus 150000.0 4 * -2.1.3.6 * enterococcus faecalis 230000.0 5 PMID:116850;PMID:17028272;PMID:22363663 -2.1.3.6 * lathyrus sativus 56000.0 2 PMID:6895223 -2.1.3.7 * amycolatopsis lactamdurans 57149.0 1 PMID:7557411 -2.1.4.1 * cylindrospermopsis raciborskii 185000.0 7 PMID:20718864;PMID:22221800 -2.1.4.1 * glycine max 240000.0 1 PMID:12453570 -2.1.4.1 * homo sapiens 91800.0 3 PMID:3800397;PMID:9915841 -2.1.4.1 * rattus norvegicus 84000.0 8 PMID:3800397;PMID:6766137;PMID:8021264 -2.1.4.1 * sus scrofa 100000.0 2 PMID:14304853 -2.1.4.2 * streptomyces griseus 80300.0 3 PMID:3029728;PMID:9915841 -2.1.5.1 * sinomonas sp. no.22 150000.0 1 PMID:27444012 -2.2.1.1 * bacillus methanolicus 280000.0 2 PMID:24405865 -2.2.1.1 * cereibacter sphaeroides 122000.0 2 PMID:15130781 -2.2.1.1 * chlamydomonas reinhardtii 156000.0 1 PMID:28552632 -2.2.1.1 * cucumis sativus 80620.0 1 PMID:23860231 -2.2.1.1 * cyberlindnera jadinii 163000.0 2 PMID:21841 -2.2.1.1 * escherichia coli 145000.0 3 PMID:18490188;PMID:7607225 -2.2.1.1 * homo sapiens 136000.0 9 PMID:18550470;PMID:20673211;PMID:2495942;PMID:3089282;PMID:5141430;PMID:7154948 -2.2.1.1 * leishmania mexicana 71800.0 2 PMID:15149284 -2.2.1.1 * ligilactobacillus salivarius 138800.0 2 PMID:26457526 -2.2.1.1 * oryctolagus cuniculus 162000.0 1 PMID:3396324 -2.2.1.1 * plasmodium falciparum 70000.0 1 PMID:18456347 -2.2.1.1 * rattus norvegicus 148000.0 5 PMID:3947099;PMID:6759853;PMID:6847198 -2.2.1.1 * saccharomyces cerevisiae 159000.0 4 PMID:6759853;PMID:8999873 -2.2.1.1 * saccharomyces pastorianus 100000.0 2 PMID:4212442 -2.2.1.1 * saccharum officinarum 70000.0 1 PMID:24132392 -2.2.1.1 * spinacia oleracea 160000.0 3 PMID:9523694 -2.2.1.1 * sus scrofa 138000.0 3 PMID:6759853;PMID:7448192 -2.2.1.1 * triticum aestivum 150000.0 2 PMID:24271866 -2.2.1.2 * acidithiobacillus ferrooxidans 23609.0 2 PMID:16202233 -2.2.1.2 * arthrobacter sp. 52000.0 3 * -2.2.1.2 * bacillus methanolicus 54000.0 1 PMID:32204692 -2.2.1.2 * blastobotrys adeninivorans 140000.0 6 PMID:17221198 -2.2.1.2 * bos taurus 65000.0 1 PMID:5025625 -2.2.1.2 * carcinus maenas 36200.0 1 PMID:21153090 -2.2.1.2 * cyberlindnera jadinii 77400.0 7 PMID:556924 -2.2.1.2 * escherichia coli 75000.0 3 PMID:18687684;PMID:7592346 -2.2.1.2 * fusarium oxysporum 38000.0 2 * -2.2.1.2 * gluconobacter oxydans 100000.0 1 PMID:14730129 -2.2.1.2 * homo sapiens 77000.0 2 PMID:18498245;PMID:18687684 -2.2.1.2 * methanocaldococcus jannaschii 271000.0 3 PMID:15810435 -2.2.1.2 * solanum lycopersicum 42000.0 2 PMID:15960612 -2.2.1.2 * thermotoga maritima 24213.0 2 PMID:21947648 -2.2.1.3 * [candida] boidinii 190000.0 10 PMID:2280716;PMID:3997860;PMID:7074134 -2.2.1.3 * acinetobacter sp. 140000.0 2 PMID:9324250 -2.2.1.3 * mycobacterium sp. 78197.0 1 PMID:18048931 -2.2.1.4 * bacillus pumilus 120000.0 1 * -2.2.1.6 * arabidopsis thaliana 113000.0 5 PMID:18234503 -2.2.1.6 * bacillus anthracis 65000.0 1 * -2.2.1.6 * bacillus subtilis 250000.0 1 PMID:234949 -2.2.1.6 * brassica napus 132000.0 4 PMID:18234503 -2.2.1.6 * enterobacter cloacae 200000.0 2 * -2.2.1.6 * enterococcus faecalis 60200.0 3 PMID:23199739;PMID:24527770;PMID:25128823 -2.2.1.6 * escherichia coli 130000.0 12 PMID:21071847;PMID:3071719;PMID:370104;PMID:6308579;PMID:6360995;PMID:9581571 -2.2.1.6 * geobacillus stearothermophilus 63300.0 2 PMID:14702326 -2.2.1.6 * gossypium hirsutum 50000.0 1 PMID:18234503 -2.2.1.6 * haemophilus influenzae 63700.0 1 PMID:17718999 -2.2.1.6 * helianthus annuus 50000.0 1 PMID:18234503 -2.2.1.6 * hordeum vulgare 460000.0 8 PMID:14536028 -2.2.1.6 * klebsiella aerogenes 220000.0 3 PMID:5560406;PMID:5823101 -2.2.1.6 * klebsiella pneumoniae 60000.0 1 PMID:23199739;PMID:24527770;PMID:25128823 -2.2.1.6 * lactococcus lactis 172000.0 4 PMID:1624471 -2.2.1.6 * leuconostoc lactis 277000.0 4 PMID:7672395 -2.2.1.6 * leuconostoc mesenteroides 150000.0 2 PMID:2684671 -2.2.1.6 * mycobacterium tuberculosis 300000.0 6 PMID:16111681;PMID:23931689;PMID:24731825 -2.2.1.6 * neurospora crassa 456000.0 1 PMID:4263405 -2.2.1.6 * nicotiana plumbaginifolia 48000.0 1 PMID:10487214 -2.2.1.6 * nicotiana tabacum 50000.0 1 PMID:18234503 -2.2.1.6 * oryza sativa japonica group 256000.0 1 PMID:32070060 -2.2.1.6 * pseudomonas aeruginosa 600000.0 3 PMID:4201533;PMID:4201534 -2.2.1.6 * pseudomonas sp. 62000.0 1 PMID:21638043 -2.2.1.6 * saccharomyces cerevisiae 150000.0 3 PMID:18234503;PMID:2684671 -2.2.1.6 * salmonella enterica subsp. enterica serovar typhimurium 140000.0 3 PMID:3907697 -2.2.1.6 * serratia marcescens 204000.0 4 PMID:2684671;PMID:8507653 -2.2.1.6 * synechocystis sp. 65000.0 1 PMID:16453101 -2.2.1.6 * thermotoga maritima 156800.0 15 * -2.2.1.6 * triticum aestivum 128000.0 4 * -2.2.1.6 * zea mays 440000.0 3 PMID:16665267 -2.2.1.7 * agrobacterium tumefaciens 135000.0 4 PMID:17188774;PMID:18050926 -2.2.1.7 * bacillus subtilis 70000.0 1 PMID:10217421 -2.2.1.7 * botryococcus braunii 83100.0 6 PMID:22325894 -2.2.1.7 * elaeis guineensis 76400.0 1 * -2.2.1.7 * escherichia coli 69000.0 2 PMID:10648511;PMID:9482846 -2.2.1.7 * glycine max 76400.0 1 PMID:18437529 -2.2.1.7 * mentha x piperita 71000.0 1 PMID:9482845 -2.2.1.7 * mycobacterium tuberculosis 67800.0 1 PMID:18783951 -2.2.1.7 * plasmodium falciparum 105800.0 1 PMID:26699947 -2.2.1.7 * plasmodium vivax 260000.0 4 PMID:23772383 -2.2.1.7 * rhodobacter capsulatus 70500.0 2 PMID:11114895 -2.2.1.7 * solanum lycopersicum 77600.0 1 PMID:10886770 -2.2.1.7 * solanum tuberosum 77800.0 1 PMID:26795152 -2.2.1.7 * streptomyces sp. 70000.0 2 PMID:10648511 -2.2.1.7 * synechocystis sp. 69000.0 1 PMID:10217421 -2.2.1.7 * vitis vinifera 77000.0 1 PMID:21868399 -2.2.1.7 * withania somnifera 77480.0 1 PMID:22526204 -2.2.1.7 * wurfbainia villosa 77150.0 1 PMID:22707144 -2.2.1.8 * streptantibioticus cattleyicolor 120000.0 2 PMID:12404452 -2.2.1.9 * bacillus subtilis 290000.0 1 PMID:20600129 -2.2.1.9 * escherichia coli k-12 62000.0 2 PMID:18983854;PMID:19338755 -2.3.1.1 * corynebacterium glutamicum 37200.0 2 PMID:24138314 -2.3.1.1 * danio rerio 55498.0 4 PMID:24465614 -2.3.1.1 * escherichia coli 51700.0 1 PMID:16890 -2.3.1.1 * homo sapiens 220100.0 3 PMID:23894642;PMID:26068232;PMID:3911000;PMID:7126172 -2.3.1.1 * maricaulis maris 263000.0 1 PMID:27934952 -2.3.1.1 * mus musculus 300000.0 1 PMID:27934952 -2.3.1.1 * mycobacterium tuberculosis 21000.0 4 PMID:15838030 -2.3.1.1 * neisseria gonorrhoeae 330000.0 1 PMID:19095660 -2.3.1.1 * neurospora crassa 73000.0 1 PMID:8939437 -2.3.1.1 * pseudomonas aeruginosa 49070.0 1 PMID:18319063 -2.3.1.1 * rattus norvegicus 300000.0 3 PMID:25771;PMID:3911000;PMID:6885773 -2.3.1.1 * sus scrofa 40322.0 2 PMID:20931344 -2.3.1.1 * xanthomonas campestris 277000.0 1 PMID:27934952 -2.3.1.1 * xylella fastidiosa 38800.0 3 PMID:25615976 -2.3.1.101 * archaeoglobus fulgidus 125000.0 2 PMID:8481089 -2.3.1.101 * methanopyrus kandleri 35000.0 5 PMID:11265475;PMID:1483480;PMID:15046586;PMID:7601152 -2.3.1.101 * methanosarcina barkeri 32000.0 2 PMID:2261993;PMID:8593103 -2.3.1.101 * methanothermobacter thermautotrophicus 41000.0 2 PMID:2261993;PMID:8593103 -2.3.1.101 * methanothermus fervidus 41000.0 2 PMID:7506350 -2.3.1.101 * methylorubrum extorquens 310000.0 1 PMID:11532013 -2.3.1.101 * uncultured archaeon 31864.0 1 PMID:24707918 -2.3.1.102 * escherichia coli 200000.0 3 PMID:2935523;PMID:3521734 -2.3.1.103 * raphanus sativus 55000.0 1 * -2.3.1.107 * catharanthus roseus 54000.0 5 PMID:24232684;PMID:9681034 -2.3.1.108 * bos taurus 62000.0 1 PMID:8135364;PMID:9118990 -2.3.1.108 * chlamydomonas reinhardtii 130000.0 2 PMID:3733880;PMID:9118990 -2.3.1.109 * pseudomonas aeruginosa 150000.0 4 PMID:7523119 -2.3.1.110 * capsicum annuum 28221.0 2 PMID:11382813;PMID:16384907 -2.3.1.110 * lavandula angustifolia 50600.0 1 PMID:21424826 -2.3.1.110 * nicotiana tabacum 55000.0 5 PMID:10469131;PMID:9288939 -2.3.1.110 * papaver somniferum 50000.0 2 PMID:10467029 -2.3.1.110 * solanum tuberosum 30000.0 2 PMID:9933628 -2.3.1.110 * zea mays 40000.0 1 PMID:10879473 -2.3.1.111 * mycobacterium tuberculosis 490000.0 2 PMID:3880746 -2.3.1.111 * mycolicibacterium smegmatis 238000.0 1 PMID:3880746 -2.3.1.112 * arachis hypogaea 40000.0 2 PMID:6497391 -2.3.1.113 * arachis hypogaea 51000.0 2 PMID:6497391 -2.3.1.114 * arachis hypogaea ssp. fastigiata 45000.0 1 PMID:6497391 -2.3.1.114 * glycine max 48000.0 2 PMID:1832837 -2.3.1.115 * cicer arietinum 112000.0 1 PMID:6497385 -2.3.1.115 * petroselinum crispum 50000.0 2 PMID:6639051;PMID:7259181 -2.3.1.116 * petroselinum crispum 50000.0 2 PMID:6639051;PMID:7259181 -2.3.1.117 * escherichia coli 72000.0 3 PMID:6365916 -2.3.1.117 * mycobacterium tuberculosis 100000.0 1 PMID:18765924 -2.3.1.117 * pseudomonas aeruginosa 110000.0 1 PMID:22359568 -2.3.1.118 * enterobacter sp. cz-1 66000.0 2 PMID:31676473 -2.3.1.118 * escherichia coli 60000.0 2 PMID:10806332 -2.3.1.118 * homo sapiens 33500.0 1 PMID:7627960 -2.3.1.118 * mesocricetus auratus 33000.0 1 PMID:3293663;PMID:3745141 -2.3.1.118 * oryctolagus cuniculus 33000.0 1 PMID:7400152 -2.3.1.118 * rattus norvegicus 32000.0 1 PMID:7687201 -2.3.1.118 * salmonella enterica subsp. enterica serovar typhimurium 48000.0 3 PMID:1569093;PMID:3890753;PMID:9535705 -2.3.1.12 * arabidopsis thaliana 80000.0 6 PMID:10364395;PMID:21798751;PMID:6430694;PMID:7890655 -2.3.1.12 * azotobacter vinelandii 1560000.0 9 PMID:1935951;PMID:2917567;PMID:3169263;PMID:3292237;PMID:3691494;PMID:6714233 -2.3.1.12 * bacillus subtilis 59000.0 1 * -2.3.1.12 * bos taurus 2800000.0 6 PMID:2642901;PMID:6546521;PMID:6768590;PMID:6778866;PMID:6780350;PMID:6893315;PMID:7144580;PMID:8958245 -2.3.1.12 * escherichia coli 1548000.0 23 PMID:12651118;PMID:1935951;PMID:23580650;PMID:24742683;PMID:25210042;PMID:388441;PMID:389239;PMID:3903169;PMID:4584392;PMID:4900507;PMID:4934679;PMID:5335914;PMID:5335915;PMID:6373436;PMID:6430694;PMID:7030782;PMID:7890655 -2.3.1.12 * geobacillus stearothermophilus 64260.0 4 PMID:2253629;PMID:7458900;PMID:9280309 -2.3.1.12 * homo sapiens 200000.0 3 PMID:9045657;PMID:9184165 -2.3.1.12 * mammalia 3100000.0 2 PMID:6546521 -2.3.1.12 * mesomycoplasma hyopneumoniae 33100.0 1 PMID:14597175 -2.3.1.12 * mus musculus 59000.0 2 PMID:12108679 -2.3.1.12 * neisseria meningitidis 70000.0 1 PMID:6893315;PMID:8958245 -2.3.1.12 * rattus norvegicus 127000.0 2 PMID:2950858;PMID:6412756 -2.3.1.12 * saccharomyces cerevisiae 48546.0 1 PMID:3050999 -2.3.1.12 * salmonella enterica subsp. enterica serovar typhimurium 87000.0 1 PMID:7052136 -2.3.1.12 * sus scrofa 1970000.0 3 PMID:1194249 -2.3.1.12 * syntrophotalea carbinolica 500000.0 4 PMID:1898934 -2.3.1.12 * zea mays 2700000.0 3 PMID:10419491 -2.3.1.122 * mycobacterium avium 33000.0 1 PMID:18703502 -2.3.1.122 * mycobacterium tuberculosis 30000.0 1 PMID:11940150 -2.3.1.122 * mycolicibacterium smegmatis 32000.0 2 PMID:19857528;PMID:3654621 -2.3.1.129 * escherichia coli 90000.0 7 PMID:1495425;PMID:19604481;PMID:8366124 -2.3.1.129 * helicobacter pylori 29855.0 1 PMID:14579368 -2.3.1.129 * moraxella catarrhalis 84000.0 1 PMID:28057571 -2.3.1.13 * bos taurus 36000.0 3 PMID:10630424;PMID:457678;PMID:6276655 -2.3.1.13 * homo sapiens 56000.0 4 PMID:10630424;PMID:23237781;PMID:7802672 -2.3.1.13 * macaca mulatta 24000.0 1 PMID:931988 -2.3.1.13 * mus musculus 34000.0 2 PMID:24576660 -2.3.1.13 * ovis aries 33000.0 1 PMID:7833837 -2.3.1.133 * cichorium endivia 58000.0 2 * -2.3.1.133 * coffea canephora 50000.0 3 PMID:22750875 -2.3.1.133 * coleus scutellarioides 47100.0 1 PMID:21318289 -2.3.1.133 * cynara cardunculus 50000.0 1 PMID:19292932 -2.3.1.133 * cynara cardunculus var. scolymus 50000.0 1 PMID:19292932 -2.3.1.133 * equisetum arvense 50000.0 1 PMID:12226354 -2.3.1.133 * ocimum basilicum 48000.0 1 PMID:12428018 -2.3.1.133 * phoenix dactylifera 40000.0 1 * -2.3.1.133 * populus x canadensis 70000.0 1 * -2.3.1.133 * raphanus sativus 40000.0 1 * -2.3.1.133 * sorghum bicolor 49000.0 1 PMID:23624856 -2.3.1.133 * trifolium pratense 48300.0 3 PMID:19525325 -2.3.1.135 * bos taurus 25000.0 1 PMID:16054134 -2.3.1.135 * homo sapiens 40000.0 8 PMID:12755610;PMID:15939047;PMID:19607828;PMID:22260449 -2.3.1.136 * escherichia coli 26800.0 1 PMID:17519228 -2.3.1.136 * neisseria meningitidis 105000.0 3 PMID:18220415 -2.3.1.137 * bos taurus 70260.0 2 PMID:9288928 -2.3.1.137 * homo sapiens 70000.0 2 PMID:10486279 -2.3.1.137 * mus musculus 66000.0 2 PMID:6436243;PMID:6838215 -2.3.1.137 * rattus norvegicus 70000.0 6 PMID:15155769;PMID:3342008;PMID:8440734 -2.3.1.138 * nicotiana tabacum 50000.0 3 PMID:16668786 -2.3.1.14 * macaca fuscata 30000.0 1 PMID:1673104 -2.3.1.140 * coleus scutellarioides 47932.0 1 PMID:17047986 -2.3.1.140 * lavandula angustifolia 50600.0 1 PMID:21424826 -2.3.1.140 * salvia miltiorrhiza 49070.0 6 PMID:39490649 -2.3.1.142 * rattus norvegicus 243000.0 3 PMID:2318887 -2.3.1.143 * quercus rubra 260000.0 2 PMID:2757399 -2.3.1.144 * dianthus caryophyllus 53000.0 2 PMID:9426598 -2.3.1.146 * pinus densiflora 42000.0 2 PMID:11880657 -2.3.1.15 * cucurbita moschata 40500.0 5 PMID:11134424 -2.3.1.15 * escherichia coli 88000.0 2 PMID:1860841;PMID:7026564 -2.3.1.15 * helianthus annuus 60100.0 2 PMID:20044264;PMID:25618244 -2.3.1.15 * homo sapiens 94000.0 5 PMID:17541789;PMID:18238778;PMID:19336658;PMID:29799006 -2.3.1.15 * lathyrus oleraceus 42000.0 3 PMID:16661974;PMID:1932680 -2.3.1.15 * leishmania major 75000.0 1 PMID:15819633 -2.3.1.15 * macrobrachium borellii 70000.0 1 PMID:19130111 -2.3.1.15 * mammalia 90000.0 2 PMID:18658143;PMID:29799006 -2.3.1.15 * metarhizium robertsii 84900.0 1 PMID:24077712 -2.3.1.15 * mus musculus 94000.0 6 PMID:17013544;PMID:17689486;PMID:19336658;PMID:29799006 -2.3.1.15 * rattus norvegicus 105000.0 4 PMID:1495436;PMID:17493869;PMID:7961630 -2.3.1.15 * solanum lycopersicum 48000.0 1 PMID:17541789;PMID:18238778 -2.3.1.15 * theobroma cacao 200000.0 2 PMID:3941071 -2.3.1.15 * umbelopsis ramanniana 45000.0 1 PMID:11284717 -2.3.1.150 * papaver somniferum 52600.0 2 PMID:11404355;PMID:8537369 -2.3.1.151 * garcinia mangostana 88000.0 3 PMID:22390826 -2.3.1.151 * hypericum androsaemum 42800.0 1 PMID:12795704 -2.3.1.153 * arabidopsis thaliana 57000.0 3 PMID:17292360 -2.3.1.153 * gentiana triflora 52000.0 2 PMID:9363752 -2.3.1.155 * brassica napus 53000.0 2 PMID:9257706 -2.3.1.155 * rattus norvegicus 89000.0 9 PMID:1730633;PMID:3036803;PMID:6117552 -2.3.1.156 * humulus lupulus 110000.0 2 PMID:10336650 -2.3.1.157 * escherichia coli 50100.0 4 PMID:11084021;PMID:8083170 -2.3.1.157 * mycobacterium tuberculosis 54100.0 2 PMID:18573680;PMID:22669463 -2.3.1.157 * yersinia pseudotuberculosis 52965.0 1 PMID:25417006 -2.3.1.158 * aurantiochytrium sp. sd116 87000.0 1 PMID:37752571 -2.3.1.158 * camelina sativa 74321.0 5 PMID:28679505 -2.3.1.158 * chlamydomonas reinhardtii 120000.0 3 PMID:23012436 -2.3.1.158 * linum usitatissimum 79072.0 2 PMID:23824186 -2.3.1.158 * saccharomyces cerevisiae 95000.0 4 PMID:18037386;PMID:30706417 -2.3.1.159 * huperzia serrata 45831.0 1 PMID:17250741 -2.3.1.159 * ruta graveolens 82000.0 8 PMID:10217426;PMID:7727746;PMID:8148006 -2.3.1.16 * arabidopsis thaliana 100000.0 2 PMID:16630629 -2.3.1.16 * candida tropicalis 98000.0 2 PMID:2575092 -2.3.1.16 * cucumis sativus 90000.0 2 PMID:11925043;PMID:7380394;PMID:7754706 -2.3.1.16 * cupriavidus necator 168000.0 2 PMID:344310 -2.3.1.16 * escherichia coli 270000.0 5 PMID:32171906;PMID:7012144;PMID:7024730 -2.3.1.16 * helianthus annuus 75000.0 3 PMID:11925043;PMID:14680958;PMID:7380394;PMID:7754706 -2.3.1.16 * pseudomonas fragi 240000.0 3 PMID:2361950 -2.3.1.16 * rattus norvegicus 460000.0 11 PMID:10064897;PMID:1730633;PMID:6117552 -2.3.1.16 * saccharomyces cerevisiae 86000.0 2 PMID:11925043;PMID:7380394;PMID:7754706 -2.3.1.16 * sus scrofa 200000.0 2 PMID:344310 -2.3.1.16 * thermus thermophilus 182000.0 2 PMID:15786714 -2.3.1.160 * rauvolfia serpentina 31000.0 1 * -2.3.1.160 * rauvolfia serpentina x rhazya stricta 50000.0 3 PMID:15110859;PMID:15110860 -2.3.1.161 * aspergillus terreus 335000.0 7 PMID:11386351;PMID:17466016 -2.3.1.162 * taxus brevifolia 50000.0 1 PMID:16161138 -2.3.1.162 * taxus canadensis 50000.0 2 PMID:10190984;PMID:10666320 -2.3.1.162 * taxus cuspidata 50000.0 1 PMID:10190984 -2.3.1.162 * taxus x media 49000.0 1 * -2.3.1.163 * taxus cuspidata 71000.0 2 PMID:10192963 -2.3.1.164 * aspergillus nidulans 40000.0 1 PMID:12709055 -2.3.1.164 * penicillium chrysogenum 40000.0 17 PMID:12709055;PMID:15802222;PMID:18439860;PMID:19156454;PMID:21695507;PMID:7519594;PMID:7557412;PMID:8082826;PMID:8224864 -2.3.1.165 * penicillium griseofulvum 750000.0 3 PMID:18412189 -2.3.1.166 * taxus brevifolia 50000.0 1 PMID:16161138 -2.3.1.166 * taxus cuspidata 52000.0 3 PMID:11095755;PMID:20108947 -2.3.1.166 * taxus x media 50090.0 1 * -2.3.1.167 * taxus brevifolia 50000.0 1 PMID:16161138 -2.3.1.167 * taxus chinensis 49000.0 1 PMID:38893462 -2.3.1.167 * taxus cuspidata 50000.0 3 PMID:10639122;PMID:19007225 -2.3.1.167 * taxus mairei 65000.0 1 PMID:29796788 -2.3.1.167 * taxus x media 65000.0 3 PMID:17094009 -2.3.1.168 * bos taurus 1116000.0 4 PMID:1943690;PMID:2416750;PMID:4055756;PMID:6746648;PMID:7913832 -2.3.1.168 * oncorhynchus mykiss 54000.0 1 PMID:12031470 -2.3.1.169 * carboxydothermus hydrogenoformans 82900.0 2 PMID:14699043 -2.3.1.169 * methanosarcina barkeri 1600000.0 6 PMID:1939246 -2.3.1.169 * neomoorella thermoacetica 310000.0 3 PMID:12386327;PMID:1995618;PMID:2911576;PMID:32135171 -2.3.1.17 * homo sapiens 33900.0 1 PMID:26550943 -2.3.1.17 * rattus norvegicus 670000.0 1 PMID:12887681 -2.3.1.171 * chrysanthemum x morifolium 51224.0 1 * -2.3.1.172 * arabidopsis thaliana 57000.0 3 PMID:17292360 -2.3.1.172 * salvia splendens 50723.0 3 PMID:11598135 -2.3.1.174 * pseudomonas sp. 162000.0 3 PMID:11741862;PMID:11741863 -2.3.1.175 * hapsidospora chrysogena 70000.0 4 PMID:1368946;PMID:9895280 -2.3.1.176 * helicoverpa armigera 16293.0 2 PMID:26655641 -2.3.1.176 * homo sapiens 15401.0 2 PMID:18465878 -2.3.1.176 * mus musculus 15000.0 2 PMID:17543577 -2.3.1.176 * spodoptera litura 16000.0 1 PMID:19912624 -2.3.1.177 * malus domestica 43000.0 3 PMID:22158676 -2.3.1.177 * pyrus communis 43050.0 2 PMID:27410389 -2.3.1.177 * sorbus aucuparia 43100.0 2 PMID:19757094 -2.3.1.178 * halomonas elongata 45000.0 1 PMID:9864317 -2.3.1.178 * methylophaga alcalica 40000.0 4 PMID:18410346;PMID:21419912 -2.3.1.178 * methylophaga thalassica 40000.0 4 PMID:18410346;PMID:21419912 -2.3.1.178 * methylotuvimicrobium alcaliphilum 40000.0 4 PMID:16212543;PMID:21419912 -2.3.1.178 * paenibacillus lautus 39730.0 1 PMID:31969391 -2.3.1.179 * arabidopsis thaliana 57600.0 1 PMID:18506098 -2.3.1.179 * brassica napus 87800.0 1 * -2.3.1.179 * elaeis guineensis 60451.0 1 PMID:24678202 -2.3.1.179 * elaeis oleifera 59878.0 1 PMID:24678202 -2.3.1.179 * escherichia coli 85000.0 3 PMID:11171141;PMID:237914;PMID:7002930 -2.3.1.179 * pseudomonas aeruginosa 55000.0 1 PMID:26249693 -2.3.1.179 * spinacia oleracea 56000.0 1 PMID:16593232 -2.3.1.18 * escherichia coli 80000.0 8 PMID:17208523;PMID:3922433;PMID:6995445 -2.3.1.180 * cuphea hookeriana 43000.0 2 PMID:11161065 -2.3.1.180 * escherichia coli 65000.0 4 PMID:10733911;PMID:23581389 -2.3.1.180 * escherichia coli k-12 34800.0 2 PMID:1551888 -2.3.1.180 * helianthus annuus 42480.0 1 PMID:20221630 -2.3.1.180 * lathyrus oleraceus 75000.0 2 PMID:12624762 -2.3.1.180 * mycobacterium tuberculosis 43000.0 1 PMID:10840036 -2.3.1.180 * spinacia oleracea 63000.0 2 PMID:1328217 -2.3.1.180 * staphylococcus aureus 66700.0 3 PMID:11959561;PMID:15987898 -2.3.1.180 * streptococcus pneumoniae 34000.0 1 PMID:11375394 -2.3.1.180 * streptomyces glaucescens 72000.0 2 PMID:9721286 -2.3.1.180 * streptomyces peucetius 38000.0 2 PMID:10423255 -2.3.1.180 * streptomyces toxytricini 68000.0 1 PMID:30763089 -2.3.1.180 * xanthomonas oryzae pv. oryzae 35000.0 1 PMID:19407376 -2.3.1.181 * bacillus subtilis 14000.0 1 PMID:20882995 -2.3.1.181 * escherichia coli 29000.0 3 PMID:15642479;PMID:21209092 -2.3.1.183 * capsicum annuum 28000.0 1 PMID:18051284 -2.3.1.183 * nocardia sp. 21000.0 1 * -2.3.1.183 * nocardia sp. ab2253 19600.0 1 PMID:19420728 -2.3.1.183 * rhodococcus sp. (in: high g+c gram-positive bacteria) 44000.0 1 * -2.3.1.183 * streptomyces hygroscopicus 30000.0 1 * -2.3.1.183 * streptomyces sp. 21000.0 1 * -2.3.1.183 * streptomyces viridochromogenes 40000.0 4 PMID:17574436;PMID:3240868 -2.3.1.184 * acinetobacter sp. 20500.0 1 PMID:25926817 -2.3.1.184 * aliivibrio fischeri 87000.0 1 PMID:10482519 -2.3.1.184 * nitrosospira multiformis 22900.0 1 PMID:24271173 -2.3.1.186 * datura stramonium 66000.0 2 * -2.3.1.187 * klebsiella pneumoniae 60800.0 1 PMID:11902724 -2.3.1.187 * malonomonas rubra 61200.0 1 PMID:11902724 -2.3.1.187 * pseudomonas putida 60000.0 1 PMID:12619701 -2.3.1.188 * nicotiana tabacum 55000.0 1 * -2.3.1.19 * clostridium acetobutylicum 264000.0 4 PMID:2719475;PMID:2844725;PMID:34584034 -2.3.1.19 * clostridium beijerinckii 205000.0 2 PMID:2317039 -2.3.1.190 * alcaligenes eutrophus h16 136000.0 2 PMID:2061286 -2.3.1.190 * clostridium magnum 138000.0 3 PMID:8206840;PMID:8274006 -2.3.1.190 * pseudomonas putida 37267.0 2 PMID:7813883 -2.3.1.190 * saccharolobus solfataricus 142000.0 2 PMID:20171216 -2.3.1.190 * syntrophotalea carbinolica 177000.0 1 PMID:1898934 -2.3.1.191 * escherichia coli 108000.0 3 PMID:18422345 -2.3.1.192 * bos taurus 38937.0 4 PMID:2283662;PMID:457678;PMID:9664233 -2.3.1.194 * streptomyces sp. 63000.0 2 PMID:20534558 -2.3.1.195 * arabidopsis thaliana 51000.0 4 PMID:12226525;PMID:17163881 -2.3.1.196 * clarkia breweri 55000.0 3 PMID:12226525 -2.3.1.196 * nicotiana tabacum 51014.0 2 PMID:12226525 -2.3.1.196 * petunia x hybrida 51040.0 1 PMID:15286288 -2.3.1.196 * populus trichocarpa 52600.0 2 PMID:25561400 -2.3.1.196 * vitis labrusca 50000.0 1 PMID:16262710 -2.3.1.199 * arabidopsis thaliana 58300.0 2 PMID:10074711;PMID:12135493 -2.3.1.199 * crambe hispanica subsp. abyssinica 56400.0 1 PMID:18640603 -2.3.1.199 * gossypium hirsutum 55000.0 1 PMID:17122407 -2.3.1.199 * homo sapiens 32000.0 2 PMID:25003994 -2.3.1.199 * saccharomyces cerevisiae 32000.0 1 PMID:9546663 -2.3.1.20 * acinetobacter baylyi 97000.0 2 PMID:16938377 -2.3.1.20 * acinetobacter baylyi adp1 94100.0 3 PMID:12502715;PMID:15687201 -2.3.1.20 * arachis hypogaea 64500.0 3 PMID:16798944;PMID:23593473 -2.3.1.20 * brassica napus 2000000.0 9 PMID:11171170;PMID:11880235;PMID:17192193;PMID:25687632;PMID:30420764 -2.3.1.20 * candida tropicalis 63000.0 2 PMID:24732323 -2.3.1.20 * claviceps purpurea 48900.0 1 PMID:20023082 -2.3.1.20 * echium pitardii 54800.0 1 PMID:19412626 -2.3.1.20 * glycine max 1843000.0 5 PMID:2354202 -2.3.1.20 * haematococcus lacustris 39912.0 4 PMID:31879987 -2.3.1.20 * homo sapiens 150000.0 5 PMID:11672446;PMID:14521909;PMID:25164810 -2.3.1.20 * marinobacter nauticus 100000.0 1 PMID:24296496 -2.3.1.20 * mus musculus 50000.0 6 PMID:11481335;PMID:14521909;PMID:16877777;PMID:25974161;PMID:9789033 -2.3.1.20 * mycobacterium tuberculosis 50900.0 4 PMID:16938377 -2.3.1.20 * mycolicibacterium smegmatis 51900.0 5 PMID:16938377 -2.3.1.20 * phaeodactylum tricornutum 64500.0 1 * -2.3.1.20 * rattus norvegicus 60000.0 1 PMID:8014588 -2.3.1.20 * rhodotorula diobovata 38950.0 1 PMID:25294723 -2.3.1.20 * ricinus communis 60000.0 2 PMID:15357018 -2.3.1.20 * streptomyces avermitilis 47400.0 1 PMID:16938377 -2.3.1.20 * streptomyces coelicolor 47100.0 1 PMID:16938377 -2.3.1.20 * tetraena mongolica 57100.0 2 PMID:23480422 -2.3.1.20 * umbelopsis ramanniana 53000.0 4 PMID:11481333;PMID:9354384 -2.3.1.20 * vernonia galamensis 60200.0 2 PMID:18179805 -2.3.1.20 * zea mays 100000.0 1 PMID:11750883 -2.3.1.201 * pseudomonas aeruginosa 68180.0 6 PMID:16102001;PMID:19282284 -2.3.1.202 * helicobacter pylori 21400.0 1 PMID:25195909 -2.3.1.203 * campylobacter jejuni 62700.0 3 PMID:17087520;PMID:18198901 -2.3.1.204 * bacillus subtilis 31420.0 1 PMID:21338420;PMID:21338421 -2.3.1.205 * aspergillus fumigatus 60800.0 4 PMID:19672909 -2.3.1.206 * cannabis sativa 89000.0 4 PMID:15120113;PMID:19454282 -2.3.1.208 * malus domestica 43000.0 1 * -2.3.1.208 * sorbus aucuparia 43100.0 1 PMID:19757094 -2.3.1.209 * escherichia coli 27100.0 1 PMID:17905981 -2.3.1.21 * bos taurus 660000.0 7 PMID:2350540;PMID:3124822;PMID:3367698;PMID:3663121;PMID:6490647;PMID:7275984 -2.3.1.21 * gallus gallus 260000.0 4 PMID:3593765 -2.3.1.21 * homo sapiens 274000.0 3 PMID:17458181;PMID:2174799 -2.3.1.21 * lathyrus oleraceus 20000.0 1 * -2.3.1.21 * macrobrachium borellii 66000.0 1 PMID:19171199 -2.3.1.21 * megalobrama amblycephala 82900.0 1 PMID:26342959 -2.3.1.21 * rattus norvegicus 430000.0 15 PMID:11356163;PMID:1390753;PMID:17404155;PMID:24222496;PMID:24898781;PMID:3597441;PMID:4122526;PMID:6630173;PMID:7425647;PMID:9136891 -2.3.1.21 * sus scrofa 82000.0 1 PMID:11329295 -2.3.1.211 * oryza sativa 43000.0 1 PMID:17932040 -2.3.1.212 * polygonum cuspidatum 43000.0 1 PMID:23908031 -2.3.1.212 * rheum palmatum 83000.0 3 PMID:11389739;PMID:12226219;PMID:18391433 -2.3.1.212 * rubus idaeus 89000.0 5 PMID:12226219;PMID:18391433 -2.3.1.214 * salvia splendens 46000.0 3 PMID:15165190 -2.3.1.215 * iris x hollandica 50000.0 3 * -2.3.1.215 * perilla frutescens 50000.0 1 * -2.3.1.216 * aloe arborescens 44000.0 1 PMID:18981598 -2.3.1.217 * zingiber officinale 85470.0 2 * -2.3.1.218 * curcuma longa 85470.0 2 * -2.3.1.218 * zingiber officinale 85470.0 2 * -2.3.1.219 * zingiber officinale 85470.0 2 * -2.3.1.22 * acinetobacter sp. 94100.0 4 PMID:15687201 -2.3.1.22 * arachis hypogaea 43000.0 1 PMID:11283027 -2.3.1.22 * danio rerio 38010.0 3 PMID:20374941 -2.3.1.22 * homo sapiens 160000.0 4 PMID:12824082;PMID:25164810 -2.3.1.22 * monodelphis domestica 39130.0 3 PMID:20374941 -2.3.1.22 * mus musculus 43000.0 2 PMID:12077311;PMID:20018982 -2.3.1.22 * rattus norvegicus 37000.0 2 PMID:21312067;PMID:4016575 -2.3.1.220 * garcinia mangostana 88000.0 2 PMID:22390826;PMID:33263571 -2.3.1.220 * hypericum androsaemum 85000.0 2 PMID:19710020 -2.3.1.222 * neomoorella thermoacetica 90000.0 4 PMID:27338272 -2.3.1.222 * salmonella enterica 27000.0 1 PMID:17158662 -2.3.1.224 * clarkia breweri 58000.0 2 PMID:9628024 -2.3.1.224 * salvia splendens 46000.0 1 PMID:15165190 -2.3.1.225 * arabidopsis thaliana 34700.0 1 PMID:26537563 -2.3.1.225 * saccharomyces cerevisiae 42000.0 1 PMID:16582420 -2.3.1.226 * pectobacterium carotovorum 27575.0 1 PMID:14625287 -2.3.1.227 * escherichia coli 68000.0 2 PMID:18201574 -2.3.1.23 * bos taurus 64000.0 2 PMID:1495439;PMID:3421720;PMID:3707126;PMID:9370324 -2.3.1.23 * helianthus annuus 52370.0 3 PMID:32351524 -2.3.1.23 * homo sapiens 57200.0 4 PMID:15485873;PMID:18195019;PMID:18458083;PMID:19351971 -2.3.1.23 * mus musculus 60000.0 4 PMID:16704971;PMID:16864775;PMID:18287005 -2.3.1.23 * rattus norvegicus 225000.0 2 PMID:16864775;PMID:7357017 -2.3.1.230 * pseudomonas aeruginosa 72800.0 3 PMID:19694421;PMID:21425231 -2.3.1.231 * saccharomyces cerevisiae 80022.0 2 PMID:19287006 -2.3.1.232 * vitis labrusca 50200.0 2 PMID:16262710 -2.3.1.233 * colletotrichum lagenaria 230000.0 1 PMID:10913297 -2.3.1.233 * streptomyces coelicolor 43000.0 2 PMID:12905073;PMID:17331946 -2.3.1.233 * streptomyces griseus 40000.0 1 PMID:12139488 -2.3.1.233 * streptomyces peucetius 58000.0 1 PMID:18612244 -2.3.1.238 * aspergillus terreus 46000.0 1 PMID:10334994 -2.3.1.24 * bos taurus 260000.0 1 PMID:9655376 -2.3.1.241 * escherichia coli 80000.0 2 PMID:18656959 -2.3.1.244 * aspergillus terreus 277000.0 1 PMID:21069965 -2.3.1.246 * amycolatopsis orientalis 41593.0 1 PMID:22492619 -2.3.1.247 * brevibacterium sp. 123000.0 1 PMID:7410315 -2.3.1.247 * fusobacterium nucleatum subsp. nucleatum 120000.0 3 PMID:17166837 -2.3.1.251 * escherichia coli 40000.0 2 PMID:11013210 -2.3.1.251 * salmonella enterica subsp. enterica serovar typhimurium 40000.0 2 PMID:11013210 -2.3.1.252 * mycobacterium tuberculosis 220300.0 1 PMID:12207710 -2.3.1.253 * pseudomonas fluorescens 77000.0 2 PMID:10322017;PMID:18437267 -2.3.1.255 * drosophila melanogaster 22000.0 1 PMID:20882681 -2.3.1.255 * homo sapiens 26000.0 1 PMID:25987439 -2.3.1.255 * mus musculus 35000.0 2 PMID:19090811;PMID:25376646 -2.3.1.255 * saccharomyces cerevisiae 99000.0 2 PMID:12890471 -2.3.1.255 * schizosaccharomyces pombe 100000.0 1 PMID:31269458 -2.3.1.255 * trypanosoma brucei 27500.0 1 PMID:11163439 -2.3.1.256 * saccharomyces cerevisiae 84000.0 3 PMID:12890471 -2.3.1.258 * arabidopsis thaliana 19300.0 1 PMID:33400917 -2.3.1.258 * homo sapiens 40000.0 2 PMID:17502424;PMID:27422821 -2.3.1.258 * saccharomyces cerevisiae 19300.0 1 PMID:33400917 -2.3.1.26 * candida albicans 71300.0 2 PMID:15184069 -2.3.1.26 * homo sapiens 250000.0 11 PMID:16820149;PMID:18340009;PMID:20964445;PMID:25218443;PMID:31251920;PMID:8407899;PMID:8798656;PMID:9242919 -2.3.1.26 * mus musculus 64000.0 4 PMID:25218443;PMID:7592824;PMID:8579615;PMID:9555010 -2.3.1.26 * platyrrhini 53000.0 2 PMID:11108732 -2.3.1.26 * rattus norvegicus 213000.0 2 PMID:7592824;PMID:9242919;PMID:9555010 -2.3.1.26 * saccharomyces cerevisiae 71600.0 1 PMID:8798656 -2.3.1.26 * sus scrofa 58000.0 1 PMID:8049197 -2.3.1.262 * pseudomonas aeruginosa 72800.0 1 PMID:19694421 -2.3.1.263 * acetoanaerobium sticklandii 136000.0 5 PMID:19251850 -2.3.1.272 * pseudomonas sp. ygj3 330000.0 1 PMID:22451400 -2.3.1.273 * mycobacterium tuberculosis 111100.0 1 PMID:26324178 -2.3.1.273 * mycolicibacterium hassiacum 125200.0 1 PMID:26324178 -2.3.1.273 * mycolicibacterium smegmatis 125500.0 1 PMID:26324178 -2.3.1.277 * streptomyces griseus 45400.0 2 * -2.3.1.278 * mycobacterium tuberculosis 51809.0 1 PMID:19276083 -2.3.1.279 * mycobacterium tuberculosis 51809.0 1 PMID:19276083 -2.3.1.28 * clostridium perfringens 22500.0 1 PMID:116849 -2.3.1.28 * escherichia coli 78000.0 2 PMID:26688469;PMID:4965980 -2.3.1.28 * flavobacterium sp. 80000.0 2 PMID:3327915 -2.3.1.28 * haemophilus influenzae 24400.0 2 PMID:6178720 -2.3.1.28 * haemophilus parainfluenzae 22500.0 1 PMID:116849 -2.3.1.28 * morganella morganii 78000.0 5 * -2.3.1.28 * proteus mirabilis 22500.0 1 PMID:116849 -2.3.1.28 * pseudomonas aeruginosa 23351.0 1 PMID:9188747 -2.3.1.28 * shouchella clausii 26660.0 1 PMID:19459958 -2.3.1.28 * staphylococcus aureus 78000.0 5 PMID:1564439;PMID:25783628;PMID:4965980 -2.3.1.28 * staphylococcus sp. 22500.0 1 PMID:116849 -2.3.1.28 * streptococcus agalactiae 22500.0 1 PMID:116849 -2.3.1.28 * streptococcus pneumoniae 22500.0 1 PMID:116849 -2.3.1.28 * vibrio anguillarum 69000.0 2 PMID:3146569 -2.3.1.280 * salmonella enterica subsp. enterica serovar typhimurium 16499.0 1 PMID:16503658 -2.3.1.286 * homo sapiens 37000.0 1 PMID:25666612 -2.3.1.286 * rattus norvegicus 37000.0 1 PMID:25666612 -2.3.1.29 * bos taurus 58330.0 6 PMID:3091598;PMID:3536927;PMID:7880831;PMID:8307963 -2.3.1.29 * escherichia coli 90480.0 9 PMID:10712613;PMID:3117785 -2.3.1.29 * sus scrofa 56000.0 1 PMID:3091598;PMID:3536927 -2.3.1.29 * thermus thermophilus 85000.0 2 PMID:18071260 -2.3.1.294 * mycobacterium tuberculosis 88000.0 1 PMID:17174327 -2.3.1.295 * mycobacterium tuberculosis 431000.0 2 PMID:15611286;PMID:18613748 -2.3.1.297 * mus musculus 42000.0 2 PMID:23591958 -2.3.1.3 * rhizomucor miehei 230000.0 1 PMID:26669854 -2.3.1.30 * allium cepa 33000.0 1 PMID:12232109;PMID:15632302;PMID:15949827 -2.3.1.30 * arabidopsis thaliana 2000000.0 4 PMID:9692924 -2.3.1.30 * brassica rapa subsp. chinensis 350000.0 1 * -2.3.1.30 * brucella abortus 181000.0 2 PMID:25058332 -2.3.1.30 * camellia sinensis 38420.0 7 PMID:39337281 -2.3.1.30 * citrullus lanatus 500000.0 1 PMID:7608200 -2.3.1.30 * cyanidioschyzon merolae 43737.0 2 PMID:9622597 -2.3.1.30 * entamoeba histolytica 40000.0 6 PMID:18851994 -2.3.1.30 * escherichia coli 160000.0 4 PMID:11055390;PMID:2125278 -2.3.1.30 * glycine max 42500.0 1 PMID:16854983 -2.3.1.30 * lacticaseibacillus casei 32000.0 1 PMID:26790714 -2.3.1.30 * lathyrus oleraceus 34330.0 1 PMID:7851429 -2.3.1.30 * leishmania major 45000.0 1 PMID:20541568 -2.3.1.30 * mycobacterium tuberculosis 300000.0 6 PMID:23483228;PMID:32976971;PMID:38311199 -2.3.1.30 * mycolicibacterium smegmatis 26200.0 1 PMID:24652708 -2.3.1.30 * neisseria gonorrhoeae 193800.0 1 PMID:34890451 -2.3.1.30 * salmonella enterica subsp. enterica serovar typhimurium 163000.0 2 PMID:6986825 -2.3.1.30 * spinacia oleracea 33000.0 1 PMID:12232109;PMID:15632302;PMID:15949827 -2.3.1.30 * thermus thermophilus hb8 33000.0 1 PMID:12232109;PMID:15632302;PMID:15949827 -2.3.1.30 * trypanosoma cruzi 38400.0 1 PMID:11106665 -2.3.1.30 * vitis vinifera 323800.0 3 PMID:25741355 -2.3.1.300 * streptomyces glaucescens 72000.0 1 PMID:9721286 -2.3.1.301 * mycobacterium tuberculosis 76600.0 1 PMID:11278743 -2.3.1.304 * allochromatium vinosum 400000.0 2 PMID:7957260 -2.3.1.304 * bacillus subtilis 39320.0 1 * -2.3.1.304 * brevundimonas sp. kh11j01 226000.0 1 PMID:35533829 -2.3.1.304 * caulobacter vibrioides 73000.0 1 PMID:11739767 -2.3.1.304 * cupriavidus necator 64000.0 2 PMID:22369488 -2.3.1.304 * ectothiorhodospira shaposhnikovii 41700.0 8 PMID:14715006 -2.3.1.304 * halopiger aswanensis 80000.0 1 PMID:12139978 -2.3.1.304 * pseudomonas sp. 62300.0 1 PMID:20082371 -2.3.1.306 * saccharomyces cerevisiae 48000.0 1 PMID:8257283 -2.3.1.31 * candida albicans 45418.0 1 PMID:35887110 -2.3.1.31 * corynebacterium glutamicum 41000.0 1 PMID:9666465 -2.3.1.31 * haemophilus influenzae 73000.0 1 PMID:10913262 -2.3.1.31 * leptospira interrogans 40000.0 1 PMID:17927957;PMID:32976971 -2.3.1.31 * mycobacterium tuberculosis 40000.0 1 PMID:17927957;PMID:32976971 -2.3.1.31 * paenibacillus polymyxa 40000.0 2 PMID:1126938 -2.3.1.31 * saccharomyces cerevisiae 104000.0 1 PMID:3301801 -2.3.1.310 * geobacter metallireducens 125000.0 3 PMID:35313080 -2.3.1.315 * geobacter metallireducens 95000.0 1 PMID:25112478 -2.3.1.320 * taxus cuspidata 50546.0 2 PMID:12232048 -2.3.1.324 * ipomoea batatas 25000.0 1 * -2.3.1.33 * oreochromis niloticus 39000.0 2 PMID:24121108;PMID:7492584 -2.3.1.33 * scomber australasicus 39000.0 1 PMID:24121108;PMID:7492584 -2.3.1.331 * chryseobacterium sp. 18000.0 1 PMID:24375143 -2.3.1.331 * chryseobacterium sp. 5-3b 18000.0 1 PMID:23479412 -2.3.1.35 * citrullus lanatus 90000.0 3 PMID:16218965 -2.3.1.35 * corynebacterium glutamicum 39700.0 1 PMID:21785983 -2.3.1.35 * geobacillus stearothermophilus 110000.0 1 PMID:8473852 -2.3.1.35 * mycobacterium tuberculosis 41000.0 1 PMID:19194014 -2.3.1.35 * saccharomyces cerevisiae 57000.0 3 PMID:10753950;PMID:7705341 -2.3.1.35 * sinorhizobium meliloti 88000.0 1 PMID:26271664 -2.3.1.35 * streptomyces clavuligerus 83000.0 3 PMID:11985581 -2.3.1.36 * saccharomyces cerevisiae 53000.0 3 PMID:15375647 -2.3.1.37 * cereibacter sphaeroides 110000.0 12 PMID:1081946;PMID:312101;PMID:3702741;PMID:4537311;PMID:4543959;PMID:5315997;PMID:5316919;PMID:943394 -2.3.1.37 * gallus gallus 115000.0 5 PMID:3197910;PMID:3702741;PMID:6825676;PMID:943394 -2.3.1.37 * mus musculus 112000.0 3 PMID:8416963;PMID:8688429;PMID:9250998 -2.3.1.37 * oncorhynchus mykiss 110000.0 2 PMID:3568615 -2.3.1.37 * oryctolagus cuniculus 200000.0 1 * -2.3.1.37 * paracoccus denitrificans 68000.0 1 PMID:4722442 -2.3.1.37 * plasmodium falciparum 158000.0 2 PMID:12119044 -2.3.1.37 * rattus norvegicus 500000.0 16 PMID:447697;PMID:4624703;PMID:5082128;PMID:6185121;PMID:6766453;PMID:7354046;PMID:762045;PMID:8407861 -2.3.1.37 * rhodopseudomonas palustris 65000.0 1 * -2.3.1.37 * rhodospirillum rubrum 70000.0 1 PMID:6786365 -2.3.1.37 * saccharomyces cerevisiae 93000.0 2 PMID:6381051 -2.3.1.37 * serratia plymuthica 97000.0 2 * -2.3.1.38 * escherichia coli 61000.0 2 PMID:3291856 -2.3.1.38 * euglena gracilis 147000.0 2 PMID:6766450;PMID:8399328 -2.3.1.38 * persea sp. 18500.0 1 PMID:8018868 -2.3.1.38 * spinacia oleracea 48000.0 1 PMID:3517573;PMID:6833216 -2.3.1.38 * streptomyces collinus 185000.0 2 PMID:11570897 -2.3.1.39 * eimeria tenella 38800.0 1 PMID:22525053 -2.3.1.39 * escherichia coli 37000.0 10 PMID:1314802;PMID:1339356;PMID:4563767;PMID:4584822;PMID:7768883;PMID:8034061 -2.3.1.39 * glycine max 43000.0 1 PMID:3963823 -2.3.1.39 * mycobacterium tuberculosis 30700.0 3 PMID:11373295;PMID:16112872;PMID:17604051 -2.3.1.39 * persea americana 40500.0 1 PMID:7075600 -2.3.1.39 * pseudomonas putida 165000.0 7 PMID:9851033 -2.3.1.39 * schizochytrium sp. 68000.0 2 PMID:23292648 -2.3.1.39 * spinacia oleracea 31000.0 1 * -2.3.1.39 * streptomyces coelicolor 34110.0 1 PMID:11814333 -2.3.1.39 * trichormus variabilis 36000.0 1 * -2.3.1.4 * arabidopsis thaliana 40300.0 3 PMID:22329777 -2.3.1.4 * caenorhabditis elegans 38800.0 1 PMID:30609921 -2.3.1.4 * homo sapiens 25000.0 1 PMID:17077487 -2.3.1.4 * lacticaseibacillus casei 52000.0 1 PMID:22383248 -2.3.1.4 * mus musculus 21000.0 1 PMID:10777580 -2.3.1.4 * mycobacterium tuberculosis 54100.0 1 PMID:18573680 -2.3.1.4 * sus scrofa 24000.0 1 PMID:2390284 -2.3.1.40 * cucurbita moschata 81000.0 3 * -2.3.1.41 * arabidopsis thaliana 47000.0 1 PMID:14660674 -2.3.1.41 * bacillus subtilis 42700.0 2 PMID:10629181 -2.3.1.41 * brassica napus 87800.0 4 * -2.3.1.41 * escherichia coli 85000.0 9 PMID:11959561;PMID:237914;PMID:4561013;PMID:5327099;PMID:7002930 -2.3.1.41 * euglena gracilis 118000.0 1 PMID:6766450 -2.3.1.41 * homo sapiens 45800.0 1 PMID:15668256 -2.3.1.41 * hordeum vulgare 90000.0 3 PMID:2034657 -2.3.1.41 * petroselinum crispum 70000.0 1 * -2.3.1.41 * spinacia oleracea 90000.0 6 PMID:1328217;PMID:16593232;PMID:2034657;PMID:6830245;PMID:6833216 -2.3.1.41 * staphylococcus aureus 67600.0 2 PMID:11959561;PMID:5327099;PMID:9721286 -2.3.1.41 * streptococcus pneumoniae 60000.0 1 PMID:11375394 -2.3.1.41 * streptomyces glaucescens 72000.0 2 PMID:11959561;PMID:9721286 -2.3.1.41 * streptomyces peucetius 38000.0 1 PMID:10423255 -2.3.1.41 * xanthomonas oryzae pv. oryzae 44000.0 1 PMID:22139163 -2.3.1.42 * cavia porcellus 90000.0 2 PMID:1495441;PMID:8380974 -2.3.1.42 * homo sapiens 80000.0 3 PMID:8186247;PMID:9459311 -2.3.1.42 * leishmania major 150000.0 1 PMID:22114698 -2.3.1.42 * oryctolagus cuniculus 210000.0 2 PMID:9459311 -2.3.1.42 * rattus norvegicus 66000.0 1 PMID:9352092 -2.3.1.43 * aeromonas salmonicida 23600.0 1 PMID:7061477 -2.3.1.43 * canis lupus familiaris 66000.0 2 PMID:222331;PMID:3014276;PMID:3718996;PMID:3888276;PMID:6853549 -2.3.1.43 * capra hircus 66000.0 2 PMID:222331;PMID:3014276;PMID:3718996;PMID:3888276;PMID:6853549 -2.3.1.43 * equus caballus 64000.0 1 PMID:2824121 -2.3.1.43 * gallus gallus 64000.0 1 PMID:7592817 -2.3.1.43 * homo sapiens 95000.0 23 PMID:1252427;PMID:12637024;PMID:15249036;PMID:15544352;PMID:1901219;PMID:222331;PMID:26363122;PMID:3014276;PMID:3888276;PMID:457692;PMID:6405796;PMID:6627099;PMID:6847201;PMID:6853549;PMID:7278683;PMID:9215537 -2.3.1.43 * oryctolagus cuniculus 67000.0 2 PMID:3888276;PMID:6405796 -2.3.1.43 * sus scrofa 69000.0 4 PMID:3080314;PMID:3718996;PMID:3888276 -2.3.1.43 * toxoplasma gondii 92000.0 1 PMID:26694607 -2.3.1.45 * bos taurus 160000.0 2 PMID:17338637 -2.3.1.45 * homo sapiens 115000.0 1 PMID:20947662 -2.3.1.46 * bacillus cereus 70000.0 1 PMID:17546672 -2.3.1.46 * escherichia coli 86000.0 2 PMID:10572016 -2.3.1.46 * mycobacterium tuberculosis 40000.0 1 PMID:32976971 -2.3.1.47 * acetivibrio thermocellus 45000.0 1 PMID:22484932 -2.3.1.47 * aquifex aeolicus 45000.0 1 PMID:22484932 -2.3.1.47 * arabidopsis thaliana 52171.0 3 PMID:16299174 -2.3.1.47 * escherichia coli 44000.0 5 PMID:10642176;PMID:16557306;PMID:22484932;PMID:3058702;PMID:9765987 -2.3.1.47 * geobacillus kaustophilus 44000.0 1 PMID:22484932 -2.3.1.47 * lysinibacillus sphaericus 46000.0 2 PMID:1575677 -2.3.1.47 * mycobacterium tuberculosis 42249.0 3 PMID:16769720 -2.3.1.47 * mycolicibacterium smegmatis 42000.0 1 PMID:25286942 -2.3.1.47 * symbiobacterium thermophilum 46000.0 1 PMID:22484932 -2.3.1.47 * thermosynechococcus vestitus 45000.0 1 PMID:22484932 -2.3.1.48 * acinetobacter baumannii 64000.0 2 PMID:31786230 -2.3.1.48 * artemia salina 280000.0 2 PMID:477673 -2.3.1.48 * aspergillus nidulans 61042.0 2 PMID:15311944 -2.3.1.48 * bos taurus 200000.0 6 PMID:22543;PMID:7356970;PMID:7440547 -2.3.1.48 * drosophila melanogaster 160000.0 1 PMID:6783663 -2.3.1.48 * homo sapiens 28000.0 4 PMID:19011241 -2.3.1.48 * lathyrus oleraceus 160000.0 2 PMID:7356970 -2.3.1.48 * mus musculus 224000.0 1 PMID:19264921 -2.3.1.48 * rattus norvegicus 110000.0 4 PMID:5031160;PMID:7130185 -2.3.1.48 * saccharomyces cerevisiae 160000.0 9 PMID:15659401;PMID:17309836;PMID:3890750;PMID:6389549 -2.3.1.48 * sus scrofa 110000.0 6 PMID:2303486;PMID:6706965 -2.3.1.48 * tetrahymena thermophila 80000.0 1 PMID:10022893 -2.3.1.48 * zea mays 90000.0 5 PMID:10536152;PMID:8635608 -2.3.1.5 * bacillus anthracis 34000.0 7 PMID:17511472;PMID:17658468;PMID:17909290 -2.3.1.5 * bacillus cereus 35000.0 10 PMID:17368397;PMID:23770703;PMID:24758871;PMID:2897359 -2.3.1.5 * columba sp. 33000.0 3 PMID:6882769;PMID:7400152 -2.3.1.5 * enterobius vermicularis 44900.0 1 PMID:10413875;PMID:10464952;PMID:15340647;PMID:9853378 -2.3.1.5 * fusarium verticillioides 170000.0 4 PMID:36178468 -2.3.1.5 * gallus gallus 34000.0 3 PMID:23770703;PMID:24758871;PMID:2897359;PMID:2897360;PMID:3595092 -2.3.1.5 * homo sapiens 37000.0 10 PMID:17210686;PMID:17392017;PMID:17672512;PMID:18759501;PMID:23770703;PMID:24346836;PMID:24758871;PMID:2897359;PMID:2924904 -2.3.1.5 * klebsiella aerogenes 44900.0 1 PMID:10413875;PMID:10464952;PMID:15340647;PMID:9853378 -2.3.1.5 * klebsiella pneumoniae 44900.0 1 PMID:10413875;PMID:10464952;PMID:15340647;PMID:9853378 -2.3.1.5 * lactobacillus acidophilus 44900.0 1 PMID:10413875;PMID:10464952;PMID:15340647;PMID:9853378 -2.3.1.5 * mesorhizobium loti 34000.0 1 PMID:17658468;PMID:17909290 -2.3.1.5 * mus musculus 34000.0 5 PMID:17896208;PMID:18280460;PMID:2306276 -2.3.1.5 * musca domestica 27600.0 2 * -2.3.1.5 * mycobacterium tuberculosis 64000.0 3 PMID:18795795;PMID:23897467 -2.3.1.5 * mycobacteroides abscessus 37000.0 2 PMID:25372695 -2.3.1.5 * nocardia farcinica 36000.0 2 PMID:18778714 -2.3.1.5 * oryctolagus cuniculus 33000.0 2 PMID:6882769;PMID:7329305;PMID:7400152 -2.3.1.5 * pseudomonas aeruginosa 61000.0 3 PMID:16102001 -2.3.1.5 * rattus norvegicus 39000.0 7 PMID:16829624;PMID:3625455;PMID:44212;PMID:883970 -2.3.1.5 * streptomyces griseus 40000.0 2 PMID:17158669 -2.3.1.50 * bacteriovorax stolpii 90000.0 2 PMID:11279212;PMID:12686119;PMID:17557831 -2.3.1.50 * homo sapiens 480000.0 3 PMID:17331073;PMID:28042036 -2.3.1.50 * rattus norvegicus 65000.0 1 PMID:17086544 -2.3.1.50 * rhizorhabdus wittichii 42000.0 1 PMID:20578000 -2.3.1.50 * saccharomyces cerevisiae 90000.0 1 PMID:9133733 -2.3.1.50 * sphingobacterium multivorum 90000.0 2 PMID:11279212;PMID:12686119;PMID:17557831 -2.3.1.50 * sphingobacterium spiritivorum 90000.0 2 PMID:11279212;PMID:12686119;PMID:17557831 -2.3.1.50 * sphingomonas paucimobilis 90000.0 6 PMID:11279212;PMID:12686119;PMID:17557831 -2.3.1.51 * brassica napus 38000.0 2 PMID:10398728 -2.3.1.51 * cocos nucifera 44000.0 3 PMID:8552723 -2.3.1.51 * homo sapiens 43380.0 2 PMID:21173190 -2.3.1.51 * mus musculus 50000.0 7 PMID:11352914;PMID:19114731;PMID:24333445;PMID:26048993;PMID:26417903 -2.3.1.51 * saccharomyces cerevisiae 61180.0 1 PMID:17675291 -2.3.1.51 * shewanella livingstonensis 31000.0 1 PMID:29415144 -2.3.1.51 * sterculia foetida 43723.0 1 PMID:24204024 -2.3.1.53 * escherichia coli 24000.0 2 PMID:4943352 -2.3.1.54 * archaeoglobus fulgidus 297000.0 2 PMID:16414072 -2.3.1.54 * clostridium pasteurianum 85000.0 1 PMID:10504733;PMID:11300793;PMID:12454503;PMID:1310545;PMID:3053170;PMID:6364987;PMID:8636053 -2.3.1.54 * escherichia coli 170000.0 10 PMID:10504733;PMID:11300793;PMID:12454503;PMID:1310545;PMID:3053170;PMID:4615902;PMID:6364987;PMID:8636053 -2.3.1.54 * streptococcus equinus 180000.0 3 PMID:10966389;PMID:12089014 -2.3.1.54 * streptococcus mutans 180000.0 2 PMID:7061379 -2.3.1.54 * streptococcus salivarius 85000.0 1 PMID:8636053 -2.3.1.54 * streptococcus sanguinis 85000.0 1 PMID:8636053 -2.3.1.56 * canis lupus familiaris 180000.0 2 PMID:8149467 -2.3.1.56 * mesocricetus auratus 31000.0 2 PMID:8761433 -2.3.1.56 * rattus norvegicus 38500.0 5 PMID:4826512;PMID:6480602;PMID:8761433 -2.3.1.57 * ascaris suum 40000.0 2 PMID:2775189 -2.3.1.57 * cryptosporidium parvum 76000.0 3 PMID:17289169 -2.3.1.57 * escherichia coli 270000.0 3 PMID:23908034;PMID:31205017 -2.3.1.57 * homo sapiens 75000.0 4 PMID:11485561;PMID:7873553 -2.3.1.57 * physcomitrium patens 52000.0 1 PMID:36786691 -2.3.1.57 * rattus norvegicus 115000.0 3 PMID:6621393;PMID:7150547 -2.3.1.57 * vibrio cholerae 270000.0 3 PMID:25623305;PMID:26410587 -2.3.1.57 * zea mays 52000.0 1 PMID:36786691 -2.3.1.6 * bos taurus 106000.0 5 PMID:413884;PMID:4473518;PMID:6885755 -2.3.1.6 * caenorhabditis elegans 71000.0 1 PMID:3964827 -2.3.1.6 * catfish 140000.0 4 PMID:6774059 -2.3.1.6 * doryteuthis opalescens 200000.0 2 PMID:4521199 -2.3.1.6 * doryteuthis pealeii 300000.0 3 PMID:60139 -2.3.1.6 * drosophila melanogaster 69000.0 7 PMID:20488078;PMID:6801053;PMID:8515270 -2.3.1.6 * electrophorus electricus 80000.0 2 PMID:9679331 -2.3.1.6 * gallus gallus 69000.0 1 PMID:20487837 -2.3.1.6 * homo sapiens 69000.0 5 PMID:23840379;PMID:3748278;PMID:40;PMID:518842 -2.3.1.6 * octopus vulgaris 81000.0 2 PMID:23354679 -2.3.1.6 * rattus norvegicus 96000.0 9 PMID:15131697;PMID:1548478;PMID:15737440;PMID:40;PMID:518842;PMID:8515270 -2.3.1.6 * schistocerca gregaria 66800.0 2 PMID:3335852 -2.3.1.6 * torpedo marmorata 68300.0 1 PMID:2606102 -2.3.1.60 * escherichia coli 63000.0 2 PMID:764855 -2.3.1.61 * brucella melitensis 45000.0 1 PMID:11553602 -2.3.1.61 * coxiella burnetii 50000.0 1 PMID:10524791 -2.3.1.61 * escherichia coli 1000000.0 3 PMID:10739245;PMID:391269;PMID:4588679 -2.3.1.61 * homo sapiens 50000.0 1 PMID:15075342 -2.3.1.61 * komagataeibacter xylinus 900000.0 2 PMID:6896181 -2.3.1.61 * rattus norvegicus 50000.0 1 PMID:15075342 -2.3.1.61 * sus scrofa 1027000.0 7 PMID:10806400;PMID:4588692 -2.3.1.64 * arabidopsis thaliana 70000.0 1 PMID:19521717 -2.3.1.64 * hordeum vulgare 48000.0 3 PMID:12582168 -2.3.1.65 * bos taurus 50900.0 2 PMID:422567 -2.3.1.65 * canis lupus familiaris 45700.0 1 PMID:7295754 -2.3.1.65 * gallus gallus 65000.0 1 PMID:14158066 -2.3.1.65 * homo sapiens 118000.0 4 PMID:12239217;PMID:6884990 -2.3.1.65 * mus musculus 46525.0 2 PMID:9215542 -2.3.1.66 * streptomyces roseus 27000.0 1 PMID:7429989 -2.3.1.67 * mus musculus 60000.0 1 PMID:18285344 -2.3.1.67 * rattus norvegicus 800000.0 2 PMID:3800896 -2.3.1.69 * mentha x piperita 37000.0 1 PMID:16660375 -2.3.1.7 * aspergillus nidulans 68500.0 1 PMID:21296915 -2.3.1.7 * aspergillus niger 77000.0 2 PMID:8856942 -2.3.1.7 * bos taurus 62000.0 2 PMID:6639064 -2.3.1.7 * camelus dromedarius 59000.0 1 PMID:8979257 -2.3.1.7 * candida tropicalis 540000.0 15 PMID:3665918;PMID:6692827;PMID:6692828;PMID:7165109;PMID:8706689;PMID:8947834 -2.3.1.7 * columba sp. 75000.0 4 PMID:14285260;PMID:4026294;PMID:7417471;PMID:8979257 -2.3.1.7 * homo sapiens 60500.0 1 PMID:2351134 -2.3.1.7 * mus musculus 60000.0 2 PMID:6436243;PMID:7165109 -2.3.1.7 * rattus norvegicus 70800.0 15 PMID:15155769;PMID:1821817;PMID:6404901;PMID:6436243;PMID:7417471;PMID:8856942;PMID:8979257 -2.3.1.7 * saccharomyces cerevisiae 400000.0 2 PMID:1892891 -2.3.1.71 * bos taurus 36000.0 7 PMID:10630424;PMID:2283662;PMID:457678;PMID:6276655;PMID:8355261 -2.3.1.71 * homo sapiens 30500.0 2 PMID:10630424;PMID:7983681 -2.3.1.71 * mus musculus 34000.0 1 PMID:24576660 -2.3.1.72 * zea mays 654000.0 3 PMID:11537469;PMID:6218801 -2.3.1.74 * arabidopsis thaliana 69000.0 2 PMID:9349261 -2.3.1.74 * daucus carota 85000.0 2 PMID:4044560 -2.3.1.74 * emblica officinalis 42560.0 1 PMID:27406087 -2.3.1.74 * fagopyrum esculentum 83000.0 2 PMID:3087289 -2.3.1.74 * glycine max 83900.0 3 PMID:32725893 -2.3.1.74 * hordeum vulgare 43000.0 1 PMID:9678580 -2.3.1.74 * petroselinum crispum 77000.0 1 PMID:114396 -2.3.1.74 * phalaenopsis hybrid cultivar 42600.0 1 * -2.3.1.74 * phaseolus vulgaris 77000.0 1 * -2.3.1.74 * physcomitrium patens 120000.0 2 PMID:22949824 -2.3.1.74 * rubus idaeus 89000.0 6 PMID:11437245 -2.3.1.74 * scutellaria baicalensis 42638.0 3 * -2.3.1.74 * secale cereale 44000.0 2 * -2.3.1.74 * spinacia oleracea 88000.0 4 PMID:24226691 -2.3.1.74 * triticum aestivum 41800.0 1 PMID:18592248 -2.3.1.74 * tulipa hybrid cultivar 55000.0 1 * -2.3.1.75 * acinetobacter baylyi adp1 94100.0 4 PMID:12502715;PMID:15687201;PMID:16938377 -2.3.1.75 * euglena gracilis 41200.0 1 PMID:20195781 -2.3.1.75 * homo sapiens 38094.0 2 PMID:20374941 -2.3.1.75 * monodelphis domestica 38599.0 2 PMID:20374941 -2.3.1.75 * mus musculus 38145.0 2 PMID:20374941 -2.3.1.75 * simmondsia chinensis 40000.0 2 PMID:10712527 -2.3.1.77 * sinapis alba 18000.0 1 * -2.3.1.78 * homo sapiens 260000.0 5 PMID:16293432;PMID:19823584;PMID:20650889 -2.3.1.79 * escherichia coli 40000.0 2 PMID:1856235 -2.3.1.8 * azotobacter vinelandii 77000.0 2 PMID:20236319;PMID:21104132 -2.3.1.8 * bacillus subtilis 90000.0 3 PMID:10423526;PMID:27338272;PMID:4201530 -2.3.1.8 * chlorogonium elongatum 280000.0 2 * -2.3.1.8 * clostridium acetobutylicum 36200.0 1 PMID:8702268 -2.3.1.8 * clostridium kluyveri 70000.0 2 PMID:14087284;PMID:952869 -2.3.1.8 * escherichia coli 79500.0 3 PMID:20236319;PMID:21046341;PMID:21104132 -2.3.1.8 * fructilactobacillus sanfranciscensis 40000.0 2 PMID:11802544 -2.3.1.8 * gottschalkia acidurici 75000.0 1 PMID:16559158 -2.3.1.8 * limosilactobacillus fermentum 68000.0 1 PMID:4995446 -2.3.1.8 * methanosarcina thermophila 71300.0 7 PMID:12876371;PMID:15062079;PMID:16428419;PMID:2808380;PMID:8226623 -2.3.1.8 * neomoorella thermoacetica 90000.0 4 PMID:27338272;PMID:4201530;PMID:7287757 -2.3.1.8 * porphyromonas gingivalis 80500.0 1 PMID:31007866 -2.3.1.8 * rhodopseudomonas palustris 54500.0 2 PMID:3790263 -2.3.1.8 * salmonella enterica 490000.0 1 PMID:17339319 -2.3.1.8 * thermotoga maritima 170000.0 2 PMID:10074080 -2.3.1.8 * treponema pallidum 77960.0 2 PMID:37200262 -2.3.1.8 * veillonella parvula 80000.0 1 PMID:5012766 -2.3.1.80 * homo sapiens 29000.0 1 PMID:20392701 -2.3.1.80 * sus scrofa 34000.0 2 * -2.3.1.81 * escherichia coli 60000.0 4 PMID:16331988 -2.3.1.81 * pseudomonas aeruginosa 60000.0 2 PMID:35921328;PMID:6803830 -2.3.1.81 * serratia marcescens 18630.0 1 PMID:9727487 -2.3.1.81 * streptomyces ribosidificus 49000.0 1 PMID:16258246 -2.3.1.82 * aeromonas hydrophila 100000.0 1 PMID:37920263 -2.3.1.82 * pseudomonas aeruginosa 59000.0 2 PMID:19349516;PMID:3997703 -2.3.1.82 * salmonella enterica 35000.0 4 PMID:11297438 -2.3.1.82 * serratia marcescens 57000.0 2 PMID:3997703 -2.3.1.82 * staphylococcus aureus 55000.0 1 PMID:6305650 -2.3.1.82 * streptomyces kanamyceticus 75000.0 1 PMID:3997703 -2.3.1.84 * cladosporium cladosporioides 22000.0 1 PMID:7764365 -2.3.1.84 * cymbopogon martini 43000.0 1 PMID:23415329 -2.3.1.84 * fragaria x ananassa 43200.0 2 PMID:22563120 -2.3.1.84 * hanseniaspora valbyensis 37000.0 1 * -2.3.1.84 * musa x paradisiaca 40000.0 1 * -2.3.1.84 * saccharomyces cerevisiae 270000.0 8 PMID:11015726;PMID:28160314;PMID:7764365;PMID:8085822 -2.3.1.84 * saccharomyces pastorianus 63200.0 1 PMID:11015726 -2.3.1.84 * saccharomyces uvarum 220000.0 1 * -2.3.1.84 * solanum lycopersicum 17000.0 1 * -2.3.1.84 * vasconcellea cundinamarcensis 51400.0 1 PMID:20369803 -2.3.1.85 * columba sp. 450000.0 2 PMID:1121292;PMID:6825687 -2.3.1.85 * corynebacterium ammoniagenes 324900.0 1 PMID:8759839 -2.3.1.85 * gallus gallus 480000.0 4 PMID:12531252;PMID:6112225 -2.3.1.85 * homo sapiens 272500.0 4 PMID:10444533;PMID:7567999;PMID:8962082 -2.3.1.85 * omphalotus olearius 450000.0 2 PMID:19526720 -2.3.1.85 * oryctolagus cuniculus 250000.0 1 PMID:6549986 -2.3.1.85 * rattus norvegicus 434000.0 4 PMID:111978;PMID:457689 -2.3.1.86 * corynebacterium ammoniagenes 324900.0 1 PMID:8759839 -2.3.1.86 * homo sapiens 46000.0 2 PMID:12882974 -2.3.1.86 * mycolicibacterium phlei 1390000.0 1 PMID:4698221 -2.3.1.86 * saccharomyces cerevisiae 2400000.0 8 PMID:350874;PMID:365179;PMID:374077;PMID:6137188 -2.3.1.87 * antheraea pernyi 37000.0 2 PMID:23064182 -2.3.1.87 * bombyx mori 37000.0 2 PMID:17449311;PMID:25712907 -2.3.1.87 * drosophila melanogaster 29200.0 1 PMID:11098219 -2.3.1.87 * esox sp. 26000.0 1 PMID:11316744 -2.3.1.87 * gallus gallus 100000.0 1 PMID:16957072 -2.3.1.87 * onchocerca volvulus 37000.0 1 PMID:8740555 -2.3.1.87 * oryza sativa japonica group 40000.0 1 PMID:33682300 -2.3.1.87 * periplaneta americana 30000.0 3 PMID:11719065;PMID:16034984;PMID:9090119 -2.3.1.87 * rattus norvegicus 39000.0 6 PMID:3625455;PMID:883970 -2.3.1.9 * bacillus cereus 171900.0 1 PMID:32972748 -2.3.1.9 * bacillus subtilis 84000.0 2 PMID:18246303 -2.3.1.9 * bacopa monnieri 43000.0 2 PMID:25911059 -2.3.1.9 * bos taurus 155000.0 6 PMID:31914 -2.3.1.9 * bradyrhizobium japonicum 193000.0 3 PMID:16347774;PMID:16535684;PMID:23736;PMID:2883931 -2.3.1.9 * candida tropicalis 250000.0 4 PMID:2575092;PMID:9348092 -2.3.1.9 * caulobacter vibrioides 45000.0 1 PMID:1967602 -2.3.1.9 * clonorchis sinensis 30000.0 1 PMID:25880842 -2.3.1.9 * clostridium acetobutylicum 53000.0 2 PMID:16347774;PMID:16535684;PMID:23736;PMID:26391388;PMID:2883931 -2.3.1.9 * clostridium kluyveri 155000.0 2 PMID:4698219;PMID:6149704;PMID:6956900 -2.3.1.9 * cupriavidus necator 80000.0 2 PMID:26057808 -2.3.1.9 * dictyostelium discoideum 43445.0 3 PMID:21209787;PMID:25911059 -2.3.1.9 * enterococcus faecalis 88712.0 2 PMID:11914342 -2.3.1.9 * escherichia coli 166000.0 4 PMID:27380370;PMID:9904 -2.3.1.9 * gallus gallus 188000.0 3 PMID:4698219;PMID:6149704 -2.3.1.9 * halobacterium sp. 80000.0 3 PMID:12013440 -2.3.1.9 * helianthus annuus 164000.0 3 PMID:11925043;PMID:20011134;PMID:29372902 -2.3.1.9 * methanothermococcus thermolithotrophicus 41900.0 1 PMID:29531083 -2.3.1.9 * ostrinia scapulalis 42100.0 3 PMID:20043999 -2.3.1.9 * pyrobaculum neutrophilum 42444.0 1 PMID:21169482 -2.3.1.9 * rattus norvegicus 170000.0 5 PMID:10806397;PMID:4156910;PMID:41585 -2.3.1.9 * rhizobium sp. 180000.0 2 PMID:16347774;PMID:16535684;PMID:23736;PMID:2883931 -2.3.1.9 * saccharomyces cerevisiae 164000.0 1 PMID:11925043;PMID:29372902 -2.3.1.9 * santalum album 43000.0 1 PMID:33441887 -2.3.1.9 * streptomyces collinus 187000.0 2 PMID:11570897 -2.3.1.9 * thermus thermophilus 182000.0 2 PMID:15786714 -2.3.1.9 * zoogloea ramigera 190000.0 6 PMID:10545327;PMID:16347774;PMID:16535684;PMID:23736;PMID:2878927;PMID:2878929;PMID:2883931 -2.3.1.90 * quercus robur 400000.0 1 * -2.3.1.91 * brassica napus 65000.0 2 PMID:8382030 -2.3.1.91 * raphanus sativus 60000.0 1 * -2.3.1.91 * sinapis alba 60000.0 1 * -2.3.1.92 * arabidopsis thaliana 55000.0 2 PMID:12012238 -2.3.1.92 * raphanus sativus 52000.0 2 PMID:24178050 -2.3.1.93 * lupinus albus 50000.0 1 PMID:8195240 -2.3.1.94 * saccharopolyspora erythraea 380000.0 9 PMID:11230695;PMID:11752428;PMID:18243693 -2.3.1.95 * arachis hypogaea 90000.0 2 PMID:6427224 -2.3.1.95 * rheum palmatum 42800.0 1 PMID:25715927 -2.3.1.95 * vitis vinifera 43000.0 1 PMID:20060310 -2.3.1.97 * arabidopsis thaliana 50000.0 1 PMID:10734119;PMID:9633510 -2.3.1.97 * bos taurus 390000.0 9 PMID:10734119;PMID:1487006;PMID:19746168;PMID:3106975;PMID:7559471;PMID:9633510;PMID:9879658 -2.3.1.97 * candida albicans 51880.0 3 PMID:12401496;PMID:1569105 -2.3.1.97 * homo sapiens 65000.0 7 PMID:8601412;PMID:8717441;PMID:9450059;PMID:9506952 -2.3.1.97 * rattus norvegicus 55000.0 2 PMID:1487006;PMID:3106975 -2.3.1.97 * saccharomyces cerevisiae 55000.0 3 PMID:1487006;PMID:18324715;PMID:2198291;PMID:3106975 -2.3.1.97 * trypanosoma brucei 50500.0 1 PMID:16480339 -2.3.1.97 * trypanosoma cruzi 53700.0 2 PMID:24444291 -2.3.1.98 * solanum lycopersicum 42580.0 4 PMID:16667263;PMID:20880851 -2.3.1.99 * bambusa multiplex 47000.0 1 PMID:36305861 -2.3.1.99 * cichorium endivia 40000.0 1 * -2.3.1.99 * cynara cardunculus var. scolymus 50000.0 1 PMID:19292932 -2.3.1.99 * lonicera japonica 48000.0 1 PMID:20539970 -2.3.1.99 * malus sylvestris 40000.0 1 * -2.3.1.99 * solanum tuberosum 41500.0 2 * -2.3.2.10 * weissella viridescens 40000.0 2 PMID:14962386 -2.3.2.11 * pseudomonas aeruginosa 84000.0 4 PMID:19087229;PMID:21392131 -2.3.2.12 * escherichia coli 67000.0 1 PMID:25422305 -2.3.2.12 * mycobacterium tuberculosis 49600.0 5 PMID:24855140 -2.3.2.12 * mycolicibacterium smegmatis 49700.0 6 PMID:24855140 -2.3.2.13 * anopheles gambiae 160000.0 2 PMID:23288850 -2.3.2.13 * arabidopsis thaliana 86000.0 1 PMID:35563835 -2.3.2.13 * bacillus subtilis 33000.0 1 PMID:18249137 -2.3.2.13 * badhamia polycephala 101000.0 4 PMID:1348244;PMID:9792706 -2.3.2.13 * bos taurus 88000.0 1 PMID:2572221 -2.3.2.13 * brugia malayi 47000.0 1 * -2.3.2.13 * caenorhabditis elegans 61000.0 1 PMID:9654053 -2.3.2.13 * cavia porcellus 94000.0 10 PMID:1974250;PMID:25133673;PMID:2569868;PMID:2868387;PMID:4151471;PMID:5928192 -2.3.2.13 * chlamydomonas reinhardtii 72000.0 1 PMID:35563835 -2.3.2.13 * cucumis sativus 72000.0 1 PMID:35563835 -2.3.2.13 * glycine max 80000.0 1 PMID:2889725;PMID:8670274 -2.3.2.13 * homo sapiens 330000.0 27 PMID:11129585;PMID:11443109;PMID:15485857;PMID:15694843;PMID:1683845;PMID:18509357;PMID:1974250;PMID:23085087;PMID:25133673;PMID:25547897;PMID:2569868;PMID:2868387;PMID:2877456;PMID:2881954;PMID:2889725;PMID:2900016;PMID:4151471;PMID:7495818;PMID:8670274 -2.3.2.13 * hordeum vulgare 80000.0 1 PMID:35563835 -2.3.2.13 * loligo sp. 94000.0 1 * -2.3.2.13 * malus domestica 70000.0 1 PMID:20441570 -2.3.2.13 * mizuhopecten yessoensis 95000.0 1 * -2.3.2.13 * mus musculus 90000.0 7 PMID:19027372;PMID:21952826;PMID:22045386;PMID:22782215;PMID:2868387;PMID:2881954;PMID:2894376 -2.3.2.13 * nemipterus sp. 95000.0 1 * -2.3.2.13 * niallia circulans 45000.0 1 PMID:12529180 -2.3.2.13 * oreochromis niloticus 85000.0 1 * -2.3.2.13 * oryctolagus cuniculus 80000.0 2 PMID:15485857;PMID:25547897;PMID:7495818;PMID:9778408 -2.3.2.13 * oryzias latipes 100000.0 2 PMID:26713442 -2.3.2.13 * ovis aries 82000.0 4 PMID:9255969 -2.3.2.13 * penaeus monodon 180000.0 3 PMID:14698215;PMID:16769260 -2.3.2.13 * rattus norvegicus 100000.0 8 PMID:15474983;PMID:1676601;PMID:2572221;PMID:2873138;PMID:2873139;PMID:9894146 -2.3.2.13 * sardina pilchardus 57000.0 1 PMID:40006172 -2.3.2.13 * streptomyces hygroscopicus 45000.0 4 PMID:24242235;PMID:26272462;PMID:26481561 -2.3.2.13 * streptomyces mobaraensis 45000.0 8 PMID:16035238;PMID:24242235;PMID:26481561 -2.3.2.13 * streptomyces sp. 40000.0 1 * -2.3.2.13 * streptomyces sp. tyq1024 38000.0 1 PMID:32325545 -2.3.2.13 * tachypleus tridentatus 86000.0 1 PMID:8093242 -2.3.2.13 * zea mays 65000.0 4 PMID:15138821;PMID:17479223;PMID:20701693;PMID:21312370 -2.3.2.15 * arabidopsis halleri 54000.0 2 PMID:21369921 -2.3.2.15 * arabidopsis thaliana 56500.0 10 PMID:12514032;PMID:16384624;PMID:16766112;PMID:17626301;PMID:19653625;PMID:20074807;PMID:21134609;PMID:26018077 -2.3.2.15 * nelumbo nucifera 125480.0 1 PMID:22161260 -2.3.2.15 * noccaea caerulescens 54000.0 2 PMID:21369921 -2.3.2.15 * pteris vittata 56900.0 1 PMID:15918023 -2.3.2.15 * pyrus betulifolia 55000.0 1 * -2.3.2.15 * saccharomyces pombe 47000.0 1 PMID:16384624 -2.3.2.15 * sesbania rostrata 55800.0 4 PMID:20111680 -2.3.2.15 * silene vulgaris 95000.0 2 PMID:16594069 -2.3.2.15 * tetrahymena thermophila 52400.0 1 PMID:19168152 -2.3.2.16 * staphylococcus aureus 50000.0 2 PMID:14523106 -2.3.2.16 * weissella viridescens 40000.0 2 PMID:11083873 -2.3.2.17 * staphylococcus aureus 89300.0 3 PMID:14523106;PMID:2559314 -2.3.2.17 * staphylococcus epidermidis 49564.0 1 PMID:8973364 -2.3.2.17 * staphylococcus hominis 49369.0 1 PMID:10209768 -2.3.2.17 * staphylococcus saprophyticus 49092.0 1 PMID:10209768 -2.3.2.18 * staphylococcus aureus 95400.0 2 PMID:14523106 -2.3.2.18 * staphylococcus epidermidis 49287.0 1 PMID:8973364 -2.3.2.19 * niallia circulans 35900.0 1 PMID:17462573 -2.3.2.2 * ascaris suum 70000.0 3 PMID:6152628;PMID:8784770 -2.3.2.2 * bacillus amyloliquefaciens 64509.0 1 PMID:28120195 -2.3.2.2 * bacillus licheniformis 67000.0 8 PMID:16850301;PMID:20401515;PMID:20673217 -2.3.2.2 * bacillus pumilus 61000.0 3 PMID:17043758 -2.3.2.2 * bacillus sp. (in: firmicutes) 70000.0 3 PMID:6152628;PMID:8784770 -2.3.2.2 * bacillus subtilis 66000.0 11 PMID:1371053;PMID:20088880;PMID:24719567 -2.3.2.2 * blighia sapida 12500.0 1 * -2.3.2.2 * bos taurus 110000.0 11 PMID:32176;PMID:6103010;PMID:6114882;PMID:6135696;PMID:6148333 -2.3.2.2 * escherichia coli 58000.0 8 PMID:17094029;PMID:2877974 -2.3.2.2 * geobacillus thermodenitrificans 103000.0 3 PMID:20138205 -2.3.2.2 * helicobacter pylori 120000.0 3 PMID:16672227 -2.3.2.2 * histoplasma capsulatum 320000.0 3 PMID:18761625 -2.3.2.2 * homo sapiens 2000000.0 47 PMID:1674218;PMID:18197;PMID:19463;PMID:1973646;PMID:1978610;PMID:21447318;PMID:21712391;PMID:24533101;PMID:25377544;PMID:2568988;PMID:4442;PMID:6104548;PMID:6111348;PMID:6112969;PMID:6121700;PMID:6122564;PMID:6146549;PMID:6150450 -2.3.2.2 * lepidochelys kempii 200000.0 3 PMID:7599989 -2.3.2.2 * marthasterias glacialis 229000.0 1 PMID:2859965 -2.3.2.2 * morchella esculenta 219000.0 3 PMID:2870692 -2.3.2.2 * ovis aries 90000.0 3 PMID:1275 -2.3.2.2 * penicillium roqueforti 120000.0 3 PMID:16672227 -2.3.2.2 * phaseolus vulgaris 180000.0 1 PMID:6030345 -2.3.2.2 * picrophilus oshimae 47000.0 3 PMID:23104165 -2.3.2.2 * proteus mirabilis 80000.0 3 PMID:32176;PMID:6148333 -2.3.2.2 * pseudomonas fluorescens 57330.0 3 PMID:24232936 -2.3.2.2 * raphanus sativus 63000.0 8 PMID:16495652 -2.3.2.2 * rattus norvegicus 250000.0 16 PMID:1674218;PMID:2868390;PMID:4151995;PMID:6102912;PMID:6111348;PMID:6128031;PMID:6152628;PMID:8784770 -2.3.2.2 * saccharomyces cerevisiae 90000.0 3 PMID:4442;PMID:6122564 -2.3.2.2 * solanum lycopersicum 43000.0 1 PMID:10759537 -2.3.2.2 * sus scrofa 80000.0 1 * -2.3.2.2 * toona sinensis 90100.0 1 * -2.3.2.2 * treponema denticola 31000.0 1 PMID:12496183 -2.3.2.23 * ciona intestinalis 30000.0 1 PMID:20578064 -2.3.2.23 * cyclocybe aegerita 42000.0 3 PMID:23385757;PMID:26525192 -2.3.2.23 * vigna radiata 16500.0 1 PMID:23824688 -2.3.2.24 * clonorchis sinensis 17760.0 1 PMID:15480785 -2.3.2.24 * homo sapiens 141000.0 1 PMID:30468556 -2.3.2.24 * oryctolagus cuniculus 230000.0 1 PMID:2550069 -2.3.2.25 * homo sapiens 22400.0 1 PMID:23871895 -2.3.2.26 * homo sapiens 330000.0 5 PMID:23663701;PMID:26457515;PMID:30287686 -2.3.2.26 * mus musculus 200000.0 2 PMID:23663701;PMID:26796253 -2.3.2.26 * rattus norvegicus 113000.0 1 PMID:26796253 -2.3.2.27 * arabidopsis thaliana 55000.0 5 PMID:19224217;PMID:23402750;PMID:25704231;PMID:26556605 -2.3.2.27 * capsicum annuum 20570.0 1 PMID:21628629 -2.3.2.27 * glycine max 43118.0 1 PMID:19373563 -2.3.2.27 * homo sapiens 97000.0 1 PMID:15673284 -2.3.2.27 * oryza sativa 28800.0 1 PMID:23698632 -2.3.2.27 * rattus norvegicus 113800.0 1 PMID:12121982 -2.3.2.27 * vitis pseudoreticulata 26970.0 1 PMID:23905547 -2.3.2.3 * bacillus subtilis 100000.0 1 PMID:18241797 -2.3.2.3 * staphylococcus aureus 97000.0 1 PMID:19915718 -2.3.2.32 * homo sapiens 1758000.0 12 PMID:34595758;PMID:38605244 -2.3.2.5 * arabidopsis thaliana 34000.0 3 PMID:17261077 -2.3.2.5 * bos taurus 48500.0 2 PMID:10428492;PMID:24943989 -2.3.2.5 * carica papaya 33000.0 3 PMID:19156482;PMID:8135542 -2.3.2.5 * homo sapiens 48000.0 6 PMID:12196024;PMID:14680951;PMID:16084398;PMID:24943989;PMID:7999256 -2.3.2.5 * myxococcus xanthus 31100.0 2 PMID:20868223 -2.3.2.5 * solanum tuberosum 34000.0 3 PMID:17261077 -2.3.2.5 * sus scrofa 55000.0 1 PMID:3597387 -2.3.2.5 * zymomonas mobilis 30000.0 2 PMID:20868223 -2.3.2.8 * mus musculus 60000.0 3 PMID:19915679;PMID:21276945;PMID:25369936 -2.3.2.8 * oryctolagus cuniculus 360000.0 1 PMID:2841321 -2.3.2.8 * physcomitrium patens 77760.0 1 PMID:26428055 -2.3.2.8 * saccharomyces cerevisiae 58000.0 1 PMID:7819189 -2.3.2.8 * sus scrofa 35000.0 1 PMID:6442545 -2.3.3.1 * nitrobacter winogradskyi 250000.0 3 * -2.3.3.1 * solanum lycopersicum 104000.0 2 * -2.3.3.1 * sus scrofa 47000.0 1 PMID:1516735 -2.3.3.1 * yarrowia lipolytica 70000.0 2 * -2.3.3.10 * arabidopsis thaliana 55500.0 2 PMID:8566777 -2.3.3.10 * blattella germanica 50000.0 1 PMID:9304791 -2.3.3.10 * bos taurus 119300.0 5 PMID:2860895 -2.3.3.10 * brassica juncea 52400.0 1 PMID:24847714 -2.3.3.10 * chamaemelum nobile 50100.0 1 PMID:27005600 -2.3.3.10 * cricetinae 53000.0 1 PMID:14984735;PMID:238985;PMID:2862566;PMID:804485 -2.3.3.10 * cricetulus griseus 57250.0 1 PMID:8566777 -2.3.3.10 * enterococcus faecalis 84300.0 4 PMID:12107122 -2.3.3.10 * gallus gallus 116000.0 18 PMID:10748155;PMID:14984735;PMID:238985;PMID:2862566;PMID:30450;PMID:7775873;PMID:804485;PMID:8099358;PMID:8566777 -2.3.3.10 * haloferax volcanii 65000.0 2 PMID:23794621 -2.3.3.10 * hevea brasiliensis 51280.0 1 PMID:24682521 -2.3.3.10 * homo sapiens 120000.0 2 PMID:7913309;PMID:8566777 -2.3.3.10 * matricaria chamomilla 50700.0 1 * -2.3.3.10 * methanothermococcus thermolithotrophicus 37500.0 1 PMID:29531083 -2.3.3.10 * mus musculus 56800.0 1 PMID:18313239 -2.3.3.10 * rattus norvegicus 57370.0 1 PMID:8566777 -2.3.3.10 * saccharomyces cerevisiae 130000.0 1 PMID:4561617 -2.3.3.10 * santalum album 52000.0 1 PMID:33441887 -2.3.3.10 * sus scrofa 56000.0 2 PMID:11368018 -2.3.3.13 * arabidopsis thaliana 280000.0 8 PMID:17189332 -2.3.3.13 * cupriavidus necator 114500.0 2 PMID:16576 -2.3.3.13 * methanocaldococcus jannaschii 230000.0 1 PMID:24991690 -2.3.3.13 * mycobacterium tuberculosis 171000.0 6 PMID:18647358;PMID:19505340;PMID:22033339;PMID:25064783 -2.3.3.13 * neisseria meningitidis 56030.0 2 PMID:20117081 -2.3.3.13 * nicotiana tabacum 149670.0 2 PMID:38213928 -2.3.3.13 * saccharomyces cerevisiae 137000.0 9 PMID:25841022;PMID:3071716;PMID:325001;PMID:3275644;PMID:5079061 -2.3.3.13 * salmonella enterica subsp. enterica serovar typhimurium 50000.0 1 PMID:4551511 -2.3.3.14 * aspergillus fumigatus 280000.0 6 PMID:20363898 -2.3.3.14 * azotobacter vinelandii 89000.0 1 PMID:9294461 -2.3.3.14 * candida albicans 210300.0 6 PMID:26363118 -2.3.3.14 * flammulina velutipes 50700.0 1 PMID:25724343 -2.3.3.14 * lotus japonicus 58600.0 1 PMID:19940927 -2.3.3.14 * penicillium chrysogenum 155000.0 1 PMID:2115771 -2.3.3.14 * sulfolobus acidocaldarius 824000.0 3 PMID:31330039 -2.3.3.14 * thermus thermophilus 60000.0 1 PMID:12095615 -2.3.3.14 * yarrowia lipolytica 48442.0 1 PMID:8948100 -2.3.3.15 * acetinobacter sp. 220000.0 1 * -2.3.3.15 * castellaniella defragrans 252000.0 1 PMID:12358600 -2.3.3.15 * cupriavidus necator 66000.0 2 PMID:19648235;PMID:22797525 -2.3.3.15 * roseovarius nubinhibens 63000.0 1 PMID:19581363 -2.3.3.15 * uncultured bacterium 85000.0 1 PMID:1228172 -2.3.3.16 * acinetobacter calcoaceticus subsp. anitratus 242000.0 2 PMID:4211224 -2.3.3.16 * arabidopsis thaliana 100000.0 1 PMID:11878562;PMID:1897942;PMID:206330;PMID:24198232;PMID:457631 -2.3.3.16 * arthrobacter sp. 150000.0 1 * -2.3.3.16 * aspergillus nidulans 52200.0 1 PMID:20437151 -2.3.3.16 * aspergillus niger 80000.0 2 PMID:10689162;PMID:3130075 -2.3.3.16 * azotobacter vinelandii 330000.0 5 PMID:4211224;PMID:7819205 -2.3.3.16 * bacillus subtilis 95000.0 1 PMID:4211224 -2.3.3.16 * cicer arietinum 78000.0 1 PMID:10648103 -2.3.3.16 * citrullus lanatus 48000.0 1 PMID:24226535 -2.3.3.16 * citrus junos 51700.0 1 PMID:19466450 -2.3.3.16 * clostridium kluyveri 51100.0 1 PMID:17400742 -2.3.3.16 * cupriavidus necator 227000.0 2 PMID:9385140 -2.3.3.16 * dictyostelium discoideum 110000.0 1 PMID:195530 -2.3.3.16 * drosophila melanogaster 81000.0 2 PMID:9387145 -2.3.3.16 * escherichia coli 269000.0 4 PMID:23954305;PMID:6339275 -2.3.3.16 * fasciola hepatica 52000.0 1 PMID:23494154 -2.3.3.16 * haloarcula vallismortis 112000.0 1 * -2.3.3.16 * halobacterium salinarum 111000.0 1 * -2.3.3.16 * haloferax volcanii 105000.0 3 PMID:10397837;PMID:1321743 -2.3.3.16 * heliocidaris crassispina 100000.0 1 PMID:11878562;PMID:1897942;PMID:206330;PMID:24198232;PMID:457631 -2.3.3.16 * hyphomicrobium sp. 150000.0 1 * -2.3.3.16 * komagataeibacter europaeus 280000.0 2 PMID:11878562;PMID:8997706 -2.3.3.16 * malus baccata var. xiaojinensis 33200.0 1 * -2.3.3.16 * mesorhizobium ciceri 228000.0 1 PMID:10648103 -2.3.3.16 * methylophilus methylotrophus 150000.0 1 * -2.3.3.16 * methylorubrum extorquens 260000.0 2 PMID:9113733 -2.3.3.16 * natronobacterium gregoryi 112000.0 1 * -2.3.3.16 * natronococcus occultus 105000.0 1 * -2.3.3.16 * natronomonas pharaonis 106000.0 1 * -2.3.3.16 * nitrosomonas sp. 287000.0 2 * -2.3.3.16 * nostoc sp. pcc 7120 = fachb-418 88533.0 1 PMID:31887428 -2.3.3.16 * priestia megaterium 84000.0 4 PMID:6412681 -2.3.3.16 * pseudomonas aeruginosa 240000.0 8 * -2.3.3.16 * pseudomonas sp. 300000.0 5 PMID:11878562;PMID:1897942;PMID:206330;PMID:24198232;PMID:457631 -2.3.3.16 * puccinia striiformis f. sp. tritici 494770.0 1 PMID:30307098 -2.3.3.16 * pyrococcus furiosus 89700.0 3 PMID:21424517;PMID:8532683 -2.3.3.16 * rhodothermus marinus 280000.0 6 PMID:11878562;PMID:1897942;PMID:206330;PMID:24198232;PMID:457631;PMID:8997706 -2.3.3.16 * saccharolobus solfataricus 80000.0 3 PMID:10689162;PMID:3130075;PMID:9672679 -2.3.3.16 * saccharomyces cerevisiae 100000.0 3 PMID:11878562;PMID:1897942;PMID:206330;PMID:24198232;PMID:457631 -2.3.3.16 * staphylococcus aureus 171000.0 2 PMID:25336653 -2.3.3.16 * streptomyces diastaticus 99990.0 3 PMID:25783416 -2.3.3.16 * sulfolobus acidocaldarius 83000.0 3 * -2.3.3.16 * talaromyces trachyspermus 70000.0 1 PMID:4681059 -2.3.3.16 * tetrahymena pyriformis 49000.0 1 PMID:8537311 -2.3.3.16 * thermoplasma acidophilum 85000.0 3 * -2.3.3.16 * thermus aquaticus 98000.0 1 PMID:670934 -2.3.3.17 * arabidopsis thaliana 53200.0 5 PMID:14740211;PMID:17369439;PMID:21205930 -2.3.3.17 * brassica oleracea 42000.0 1 PMID:26569208 -2.3.3.18 * streptomyces hygroscopicus 114000.0 3 PMID:3170341;PMID:32697946 -2.3.3.19 * streptomyces hygroscopicus 98000.0 2 PMID:3170341 -2.3.3.2 * talaromyces trachyspermus 90000.0 2 PMID:5099208 -2.3.3.20 * xanthomonas campestris 62000.0 1 PMID:21266575 -2.3.3.21 * leptospira interrogans 310000.0 6 PMID:15292141;PMID:18498255;PMID:19351325 -2.3.3.3 * clostridium kluyveri 52100.0 3 PMID:17400742 -2.3.3.3 * syntrophus aciditrophicus 271000.0 4 PMID:23378508 -2.3.3.4 * talaromyces trachyspermus 43000.0 1 PMID:4774124 -2.3.3.5 * aspergillus fumigatus 514100.0 2 PMID:16008561 -2.3.3.5 * aspergillus nidulans 90000.0 3 PMID:10712680 -2.3.3.5 * aspergillus niger 51300.0 1 PMID:23832368 -2.3.3.5 * corynebacterium glutamicum 42600.0 2 PMID:11976302 -2.3.3.5 * cupriavidus metallidurans 42720.0 1 PMID:11495997 -2.3.3.5 * cupriavidus necator 43683.0 1 PMID:16133321 -2.3.3.5 * escherichia coli 43100.0 2 PMID:12473114;PMID:9325432 -2.3.3.5 * fusarium solani 49000.0 1 PMID:19661181 -2.3.3.5 * fusarium verticillioides 49000.0 1 PMID:19661181 -2.3.3.5 * mycobacterium tuberculosis 43000.0 2 PMID:25901919 -2.3.3.5 * paraburkholderia sacchari 42690.0 1 PMID:11772636 -2.3.3.8 * arabidopsis sp. 500000.0 3 PMID:12376641 -2.3.3.8 * aspergillus nidulans 550000.0 8 PMID:12009400;PMID:20495057;PMID:9244275;PMID:9450098 -2.3.3.8 * brassica napus 120000.0 1 PMID:10653665;PMID:10759519 -2.3.3.8 * chlorobaculum tepidum 550000.0 2 PMID:12009400;PMID:9244275 -2.3.3.8 * chlorobium limicola 557000.0 6 PMID:11248686;PMID:7142107 -2.3.3.8 * cyanophora paradoxa 66000.0 1 PMID:11683264 -2.3.3.8 * homo sapiens 480000.0 6 PMID:10653665;PMID:10759519;PMID:19795461;PMID:2026262;PMID:22657152;PMID:31830561;PMID:31858156;PMID:762167 -2.3.3.8 * hydrogenobacter thermophilus 260000.0 2 PMID:2703459 -2.3.3.8 * lathyrus oleraceus 470000.0 1 PMID:12376641 -2.3.3.8 * lipomyces starkeyi 510000.0 1 * -2.3.3.8 * phaffia rhodozyma 120100.0 2 PMID:26122278 -2.3.3.8 * rattus norvegicus 500000.0 10 PMID:19795461;PMID:2026262;PMID:22657152;PMID:6260494;PMID:6335031;PMID:6830253;PMID:7227519;PMID:762167;PMID:821950 -2.3.3.8 * rhodotorula toruloides 520000.0 3 PMID:2302411 -2.3.3.8 * ricinus communis 400000.0 1 PMID:16660792 -2.3.3.8 * spinacia oleracea 120000.0 1 PMID:10653665;PMID:10759519 -2.3.3.8 * talaromyces trachyspermus 200000.0 1 PMID:4730959 -2.3.3.9 * bacillus licheniformis 56000.0 1 PMID:28311 -2.3.3.9 * bacillus sp. (in: firmicutes) 62000.0 2 PMID:236948;PMID:28311;PMID:6444795 -2.3.3.9 * brassica napus 63000.0 1 PMID:7589540 -2.3.3.9 * candida tropicalis 250000.0 2 PMID:3718151 -2.3.3.9 * chlamydomonas reinhardtii 65000.0 1 PMID:14991408 -2.3.3.9 * colwellia maris 763000.0 2 PMID:11440123;PMID:6444795 -2.3.3.9 * corynebacterium glutamicum 90000.0 2 PMID:7812449 -2.3.3.9 * cucumis sativus 63000.0 1 PMID:6859877 -2.3.3.9 * cucurbita sp. 480000.0 4 * -2.3.3.9 * escherichia coli 82000.0 10 PMID:10715138;PMID:18008171;PMID:19684068;PMID:20138106;PMID:21864568;PMID:23718231;PMID:28311 -2.3.3.9 * euglena gracilis 420000.0 5 PMID:15964777;PMID:21332878;PMID:28738 -2.3.3.9 * fomitopsis palustris 520000.0 2 PMID:12005052 -2.3.3.9 * geobacillus stearothermophilus 62000.0 2 PMID:236948;PMID:28311;PMID:6444795 -2.3.3.9 * glycine max 630000.0 2 * -2.3.3.9 * gossypium hirsutum 750000.0 3 PMID:16665608 -2.3.3.9 * haloferax volcanii 200000.0 2 PMID:9738442 -2.3.3.9 * mycobacterium tuberculosis 80000.0 2 PMID:21728344;PMID:21864568 -2.3.3.9 * neurospora crassa 160000.0 2 PMID:11440123;PMID:236948;PMID:28311;PMID:6444795 -2.3.3.9 * ogataea angusta 250000.0 2 PMID:3718151 -2.3.3.9 * paracoccidioides brasiliensis 60000.0 2 PMID:19888806;PMID:20034376;PMID:23672539 -2.3.3.9 * paracoccidioides sp. 60000.0 1 PMID:20034376;PMID:23672539 -2.3.3.9 * pinus densiflora 630000.0 4 * -2.3.3.9 * pinus taeda 520000.0 2 PMID:12005052 -2.3.3.9 * pseudomonas aeruginosa 79400.0 1 PMID:19549344 -2.3.3.9 * ricinus communis 575000.0 2 PMID:16660272 -2.3.3.9 * saccharolobus solfataricus 189000.0 1 PMID:20736170 -2.3.3.9 * saccharomyces cerevisiae 186000.0 5 PMID:322663;PMID:4601336;PMID:7011808 -2.3.3.9 * streptomyces arenae 110000.0 2 PMID:9133598 -2.3.3.9 * streptomyces coelicolor 86000.0 1 PMID:11759686 -2.3.3.9 * streptomyces thermovulgaris 60900.0 1 PMID:13680388 -2.3.3.9 * vogesella indigofera 56000.0 1 PMID:28311 -2.3.3.9 * zea mays 510000.0 2 PMID:8286948 -2.4.1.1 * aquifex aeolicus 81981.0 2 * -2.4.1.1 * artemia sinica 190000.0 3 PMID:24323193 -2.4.1.1 * badhamia polycephala 172000.0 2 PMID:527584 -2.4.1.1 * chlamydomonas reinhardtii 214000.0 6 PMID:17018036 -2.4.1.1 * corynebacterium callunae 176000.0 2 PMID:12945;PMID:9307027 -2.4.1.1 * cuscuta reflexa 100000.0 1 * -2.4.1.1 * dictyostelium discoideum 95000.0 1 * -2.4.1.1 * gracilaria sordida 97400.0 1 * -2.4.1.1 * homo sapiens 175000.0 1 PMID:4512309 -2.4.1.1 * ipomoea batatas 98000.0 1 * -2.4.1.1 * klebsiella pneumoniae 174000.0 3 PMID:12945;PMID:9307027 -2.4.1.1 * lathyrus oleraceus 160000.0 2 * -2.4.1.1 * lethenteron camtschaticum 170000.0 2 PMID:20048 -2.4.1.1 * locusta migratoria 193000.0 2 * -2.4.1.1 * magallana gigas 89629.0 1 * -2.4.1.1 * manduca sexta 178000.0 2 * -2.4.1.1 * manihot esculenta 110000.0 1 PMID:6526410 -2.4.1.1 * mizuhopecten yessoensis 120000.0 1 * -2.4.1.1 * musa x paradisiaca 55000.0 1 PMID:7126533 -2.4.1.1 * neurospora crassa 180000.0 1 PMID:156719 -2.4.1.1 * oryctolagus cuniculus 195000.0 2 PMID:12519071;PMID:19146822;PMID:36989206 -2.4.1.1 * oryza sativa 106000.0 1 PMID:18621947 -2.4.1.1 * phymatotrichopsis omnivora 145000.0 2 PMID:3579319 -2.4.1.1 * pyrococcus furiosus 98000.0 2 PMID:19054743 -2.4.1.1 * saccharolobus solfataricus 69000.0 2 PMID:19682609 -2.4.1.1 * saccharomyces cerevisiae 100000.0 1 PMID:6354094 -2.4.1.1 * solanum tuberosum 210000.0 7 PMID:16151135;PMID:7325677 -2.4.1.1 * spinacia oleracea 159000.0 4 PMID:16661543;PMID:24309705 -2.4.1.1 * thermus caldophilus 550000.0 3 * -2.4.1.1 * thermus thermophilus 93000.0 1 PMID:8706700 -2.4.1.1 * triticum aestivum 110000.0 2 PMID:15564531;PMID:19524321 -2.4.1.1 * typha latifolia 112000.0 1 * -2.4.1.1 * vigna radiata 105000.0 1 PMID:15998137 -2.4.1.1 * xanthosoma sagittifolium 95000.0 1 * -2.4.1.1 * zea mays 174000.0 5 PMID:11361132;PMID:16665923;PMID:4730475 -2.4.1.10 * actinomyces viscosus 250000.0 2 PMID:105761 -2.4.1.10 * bacillus amyloliquefaciens 52000.0 3 PMID:19916084 -2.4.1.10 * bacillus licheniformis 51000.0 1 * -2.4.1.10 * bacillus sp. (in: firmicutes) 56000.0 1 PMID:12270599 -2.4.1.10 * bacillus subtilis 52000.0 5 PMID:16870166;PMID:6424671 -2.4.1.10 * bacillus velezensis 60000.0 1 PMID:25524717 -2.4.1.10 * fructilactobacillus sanfranciscensis 94930.0 1 PMID:15735966 -2.4.1.10 * gluconacetobacter diazotrophicus 200000.0 3 PMID:10441728 -2.4.1.10 * hordeum vulgare 67000.0 5 PMID:12228431;PMID:8524822 -2.4.1.10 * leuconostoc mesenteroides 103000.0 3 PMID:15652153 -2.4.1.10 * niallia circulans 52000.0 1 * -2.4.1.10 * pantoea agglomerans 48000.0 1 * -2.4.1.10 * priestia megaterium 52000.0 1 PMID:17608626 -2.4.1.10 * pseudomonas savastanoi pv. phaseolicola 68000.0 2 PMID:7751294 -2.4.1.10 * rahnella aquatilis 120000.0 3 * -2.4.1.10 * zymomonas mobilis 120000.0 6 PMID:10733894;PMID:18809687;PMID:7751294 -2.4.1.100 * allium cepa 66000.0 1 PMID:15720662 -2.4.1.100 * cichorium intybus 69000.0 3 * -2.4.1.100 * echinops ritro 52000.0 2 PMID:16449376 -2.4.1.100 * helianthus tuberosus 72800.0 2 * -2.4.1.100 * lolium rigidum 50000.0 1 * -2.4.1.100 * taraxacum officinale 49000.0 1 * -2.4.1.101 * arabidopsis thaliana 78000.0 1 PMID:19826906 -2.4.1.101 * homo sapiens 78000.0 3 PMID:19826906;PMID:25395405;PMID:8727789 -2.4.1.101 * magallana gigas 52000.0 1 PMID:38557922 -2.4.1.101 * oryctolagus cuniculus 58000.0 5 PMID:2560125;PMID:2967294;PMID:6450208 -2.4.1.101 * phaeodactylum tricornutum 56000.0 1 PMID:21169367 -2.4.1.101 * rattus norvegicus 51000.0 2 PMID:8520118;PMID:9884406 -2.4.1.101 * sus scrofa 59000.0 2 PMID:6457827 -2.4.1.101 * xenopus laevis 65000.0 1 PMID:11555621 -2.4.1.102 * homo sapiens 58000.0 1 PMID:12758148 -2.4.1.102 * sus scrofa 70000.0 1 PMID:9746219 -2.4.1.104 * nicotiana tabacum 50000.0 2 PMID:10940474 -2.4.1.109 * aspergillus nidulans 103300.0 2 PMID:19648468 -2.4.1.109 * homo sapiens 88000.0 4 PMID:19880378;PMID:20065251;PMID:21956107 -2.4.1.109 * saccharomyces cerevisiae 92000.0 3 PMID:2001697;PMID:8543034 -2.4.1.11 * ascaris suum 85000.0 1 PMID:3934170 -2.4.1.11 * bos taurus 340000.0 2 PMID:2996630 -2.4.1.11 * crypthecodinium cohnii 110000.0 1 PMID:18310353 -2.4.1.11 * dictyostelium discoideum 280000.0 2 PMID:9023987 -2.4.1.11 * homo sapiens 410000.0 2 PMID:412671;PMID:823021 -2.4.1.11 * mus musculus 84000.0 1 PMID:12510058 -2.4.1.11 * neurospora crassa 270000.0 1 PMID:23841 -2.4.1.11 * oncorhynchus mykiss 312000.0 1 PMID:4631637 -2.4.1.11 * oryctolagus cuniculus 420000.0 9 PMID:412671;PMID:6423631;PMID:814926;PMID:823021 -2.4.1.11 * phymatotrichopsis omnivora 410000.0 2 * -2.4.1.11 * pyrococcus abyssi 100000.0 2 PMID:14646108 -2.4.1.11 * saccharomyces cerevisiae 400000.0 4 PMID:10874034;PMID:2114092;PMID:2116410;PMID:4365739 -2.4.1.11 * spodoptera exigua 76190.0 1 PMID:22550018 -2.4.1.11 * sus scrofa 83700.0 2 PMID:21931959 -2.4.1.111 * picea abies 50000.0 2 PMID:6210530 -2.4.1.111 * rosa sp. 52000.0 1 PMID:10853 -2.4.1.113 * thermococcus hydrothermalis 85000.0 2 PMID:11821929 -2.4.1.115 * freesia hybrid cultivar 48043.0 1 PMID:21318353 -2.4.1.115 * glycine max 49800.0 2 PMID:20621794 -2.4.1.115 * iris x hollandica 50000.0 2 * -2.4.1.115 * pericallis hybrida 52000.0 1 * -2.4.1.115 * petunia x hybrida 78000.0 3 * -2.4.1.115 * silene dioica 125000.0 3 PMID:751640 -2.4.1.115 * solanum tuberosum 49900.0 1 PMID:20358295 -2.4.1.115 * vitis labrusca 50100.0 1 PMID:22098678 -2.4.1.115 * vitis vinifera 56000.0 1 * -2.4.1.116 * silene dioica 55000.0 1 PMID:751641 -2.4.1.117 * homo sapiens 36000.0 1 PMID:2163838 -2.4.1.117 * saccharomyces cerevisiae 38000.0 1 PMID:8076653 -2.4.1.117 * vigna radiata var. radiata 39000.0 1 PMID:16668398 -2.4.1.118 * raphanus sativus 46500.0 1 PMID:486500 -2.4.1.12 * arabidopsis thaliana 106000.0 1 PMID:33729990 -2.4.1.12 * komagataeibacter xylinus 93000.0 2 * -2.4.1.120 * brassica napus 55970.0 4 PMID:11144274;PMID:15053762 -2.4.1.121 * brassica napus 43700.0 1 PMID:14990619 -2.4.1.121 * lathyrus oleraceus 45700.0 1 PMID:14990619 -2.4.1.121 * zea mays 52000.0 3 PMID:11537438;PMID:11537439;PMID:1719957 -2.4.1.122 * gallus gallus 68000.0 1 PMID:3924026 -2.4.1.122 * homo sapiens 50000.0 4 PMID:18061573;PMID:19923218;PMID:21496458 -2.4.1.122 * rattus norvegicus 86000.0 1 PMID:11673471 -2.4.1.122 * sus scrofa 90000.0 2 PMID:6801057 -2.4.1.123 * citrus sinensis 73620.0 8 PMID:36112700 -2.4.1.123 * cucurbita pepo 36000.0 1 PMID:7480343 -2.4.1.123 * phaseolus vulgaris 38000.0 1 PMID:7480343 -2.4.1.125 * streptococcus gordonii 174000.0 1 PMID:8945555 -2.4.1.125 * streptococcus mutans 174000.0 5 PMID:2937877;PMID:6216919;PMID:6228638;PMID:6461359 -2.4.1.127 * mentha x piperita 46000.0 1 PMID:16661898 -2.4.1.128 * catharanthus roseus 51000.0 1 * -2.4.1.128 * nicotiana tabacum 45000.0 1 PMID:16662301 -2.4.1.13 * acidithiobacillus caldus 367000.0 2 PMID:27775150;PMID:32344088 -2.4.1.13 * anabaena sp. 360000.0 1 PMID:10592030 -2.4.1.13 * beta vulgaris 320000.0 4 * -2.4.1.13 * coffea arabica 92500.0 2 PMID:16926239 -2.4.1.13 * cucumis sativus 540000.0 2 PMID:24028217 -2.4.1.13 * daucus carota 320000.0 1 PMID:7784526 -2.4.1.13 * glycine max 412000.0 3 PMID:16664189;PMID:2889731 -2.4.1.13 * gossypium hirsutum 90000.0 1 PMID:21757635 -2.4.1.13 * hordeum vulgare 98700.0 3 PMID:21505865 -2.4.1.13 * ipomoea batatas 540000.0 1 * -2.4.1.13 * ipomoea nil 420000.0 3 * -2.4.1.13 * lathyrus oleraceus 410000.0 1 * -2.4.1.13 * musa acuminata 420000.0 2 * -2.4.1.13 * nicotiana tabacum 88000.0 1 PMID:18344420 -2.4.1.13 * nitrosomonas europaea 360000.0 2 PMID:26013491 -2.4.1.13 * oryza sativa 440000.0 6 PMID:4718788;PMID:9784845 -2.4.1.13 * prunus persica 360000.0 2 * -2.4.1.13 * pyrus pyrifolia 360000.0 1 PMID:10845453 -2.4.1.13 * saccharum officinarum 380000.0 2 PMID:15700416 -2.4.1.13 * solanum tuberosum 394000.0 2 PMID:14711497 -2.4.1.13 * thermosynechococcus vestitus 341000.0 2 PMID:23196182 -2.4.1.13 * triticum aestivum 380000.0 3 * -2.4.1.13 * vicia faba 353000.0 2 PMID:16653008 -2.4.1.13 * vigna radiata 350000.0 1 PMID:9339551 -2.4.1.13 * vigna radiata var. radiata 405000.0 3 PMID:4624446 -2.4.1.13 * zea mays 360000.0 3 PMID:16660299;PMID:16664445 -2.4.1.131 * saccharomyces cerevisiae 63143.0 2 PMID:11278778;PMID:19929855 -2.4.1.132 * saccharomyces cerevisiae 98500.0 2 PMID:7579696;PMID:7962051 -2.4.1.133 * bos taurus 55000.0 1 PMID:7785767 -2.4.1.133 * homo sapiens 71000.0 4 PMID:19032152;PMID:20226765;PMID:20809901;PMID:25568325 -2.4.1.134 * [haemophilus] ducreyi 33400.0 1 PMID:10735874 -2.4.1.135 * homo sapiens 85000.0 2 PMID:10842173 -2.4.1.135 * rattus norvegicus 43000.0 2 PMID:19147493;PMID:21056957 -2.4.1.136 * quercus rubra 68000.0 1 * -2.4.1.136 * trapa natans var. bispinosa 55000.0 1 PMID:36500465 -2.4.1.137 * pyropia perforata 120000.0 1 * -2.4.1.138 * kluyveromyces lactis 300000.0 1 PMID:6211189 -2.4.1.139 * spinacia oleracea 95000.0 1 PMID:24275923 -2.4.1.14 * anabaena sp. 46000.0 1 PMID:8942980 -2.4.1.14 * ipomoea batatas 540000.0 2 * -2.4.1.14 * lathyrus oleraceus 456000.0 1 * -2.4.1.14 * methylobacillus flagellatus 336000.0 2 PMID:23865613 -2.4.1.14 * neltuma juliflora 443000.0 1 * -2.4.1.14 * oryza sativa 420000.0 3 PMID:9620436 -2.4.1.14 * solanum tuberosum 120000.0 2 * -2.4.1.14 * spinacia oleracea 480000.0 10 PMID:16663357;PMID:16666575;PMID:2144103;PMID:6272652;PMID:7763376;PMID:7763823 -2.4.1.14 * synechocystis sp. 82000.0 1 PMID:12493850 -2.4.1.14 * triticum aestivum 390000.0 1 PMID:24407996 -2.4.1.14 * zea mays 480000.0 5 PMID:16668210;PMID:1840396 -2.4.1.140 * streptococcus mutans 159000.0 2 PMID:2533246;PMID:2937877 -2.4.1.141 * mesocricetus auratus 30000.0 4 PMID:19129246 -2.4.1.143 * homo sapiens 56000.0 2 PMID:18309288;PMID:7635144 -2.4.1.143 * rattus norvegicus 48000.0 3 PMID:2952644;PMID:7797505;PMID:7841796 -2.4.1.143 * sus scrofa 51100.0 1 PMID:9367162 -2.4.1.144 * homo sapiens 110000.0 5 PMID:22451656 -2.4.1.144 * mus musculus 62000.0 2 PMID:22451656 -2.4.1.144 * rattus norvegicus 68100.0 5 PMID:11011143;PMID:1325461;PMID:9376679 -2.4.1.145 * bos taurus 61610.0 2 PMID:9278430;PMID:9565571 -2.4.1.145 * homo sapiens 94000.0 3 PMID:10372966;PMID:18309288;PMID:39426160 -2.4.1.147 * homo sapiens 46600.0 2 PMID:11821425 -2.4.1.148 * bos taurus 58000.0 2 PMID:15226299 -2.4.1.149 * bos taurus 90000.0 2 PMID:8262950 -2.4.1.149 * homo sapiens 47125.0 1 PMID:9405606 -2.4.1.149 * mus musculus 45000.0 1 PMID:12061784 -2.4.1.15 * actinoplanes sp. 51000.0 1 PMID:18663442 -2.4.1.15 * arabidopsis thaliana 100000.0 1 * -2.4.1.15 * ascaris suum 66000.0 2 PMID:22571853 -2.4.1.15 * cyberlindnera jadinii 60000.0 1 PMID:19004876;PMID:21771638 -2.4.1.15 * escherichia coli 54000.0 1 PMID:11807274 -2.4.1.15 * ginkgo biloba 97000.0 1 PMID:16584630 -2.4.1.15 * halorhodospira halochloris 63000.0 1 PMID:8480996 -2.4.1.15 * helicoverpa armigera 60000.0 1 PMID:19004876;PMID:21771638 -2.4.1.15 * locusta migratoria manilensis 91976.0 1 * -2.4.1.15 * metarhizium anisopliae 58000.0 1 PMID:19393547 -2.4.1.15 * mycobacterium tuberculosis 220000.0 2 PMID:12473104 -2.4.1.15 * mycolicibacterium smegmatis 45000.0 1 PMID:637569 -2.4.1.15 * rhizopus arrhizus 97800.0 1 PMID:26567772 -2.4.1.15 * saccharomyces cerevisiae 630000.0 10 PMID:1425702;PMID:18166160;PMID:1849964 -2.4.1.15 * selaginella lepidophylla 440000.0 2 PMID:14684162 -2.4.1.15 * sulfolobus acidocaldarius 100000.0 1 PMID:33008820 -2.4.1.15 * thermoplasma acidophilum 51400.0 1 PMID:24508535 -2.4.1.15 * thermoproteus tenax 81000.0 3 PMID:23626675 -2.4.1.15 * thermus thermophilus 52000.0 1 PMID:15455210 -2.4.1.150 * sus scrofa 76000.0 1 PMID:9765297 -2.4.1.152 * apis mellifera 47000.0 1 PMID:17029591 -2.4.1.152 * bacteroides fragilis 39000.0 2 * -2.4.1.152 * helicobacter pylori 51200.0 1 PMID:16407247 -2.4.1.152 * homo sapiens 54000.0 13 PMID:15632313;PMID:17335083;PMID:1733970;PMID:1740457;PMID:17636386;PMID:18395013;PMID:20428816;PMID:23263199;PMID:7650030;PMID:8748166 -2.4.1.152 * pan troglodytes 43034.0 2 PMID:9368041 -2.4.1.152 * rattus norvegicus 40680.0 1 PMID:8729003 -2.4.1.152 * schistosoma mansoni 50556.0 1 PMID:10779604 -2.4.1.153 * methanococcus voltae 28175.0 1 PMID:23624439 -2.4.1.155 * homo sapiens 110000.0 9 PMID:10395745;PMID:11886845;PMID:17971775;PMID:18343992;PMID:18845630;PMID:19787216;PMID:8393437 -2.4.1.155 * rattus norvegicus 75000.0 2 PMID:1531335 -2.4.1.158 * pseudohyphozyma bogoriensis 52000.0 2 PMID:6213610 -2.4.1.159 * tulipa hybrid cultivar 40000.0 1 * -2.4.1.16 * absidia glauca 540000.0 3 PMID:8420947 -2.4.1.16 * aedes aegypti 179400.0 1 PMID:14610026 -2.4.1.16 * amylomyces rouxii 700000.0 1 PMID:16894 -2.4.1.16 * anopheles gambiae 186400.0 2 PMID:14610026 -2.4.1.16 * atrina rigida 66000.0 3 PMID:23643908 -2.4.1.16 * bombyx mori 123884.0 1 PMID:24338669 -2.4.1.16 * coprinopsis cinerea 67000.0 1 * -2.4.1.16 * drosophila melanogaster 182800.0 2 PMID:14610026 -2.4.1.16 * entamoeba dispar 114000.0 2 PMID:15552059 -2.4.1.16 * entamoeba histolytica 114000.0 2 PMID:15552059 -2.4.1.16 * entamoeba invadens 114000.0 2 PMID:15552059 -2.4.1.16 * exophiala dermatitidis 210000.0 1 PMID:19431044 -2.4.1.16 * lucilia cuprina 180700.0 1 PMID:14610026 -2.4.1.16 * manduca sexta 670000.0 7 PMID:14610026;PMID:19576988 -2.4.1.16 * moniliophthora perniciosa 102000.0 1 PMID:19763417 -2.4.1.16 * ostrinia furnacalis 174000.0 1 PMID:22607200 -2.4.1.16 * paracoccidioides brasiliensis 206900.0 2 PMID:19616626;PMID:20037924 -2.4.1.16 * saccharomyces cerevisiae 570000.0 1 PMID:6238967 -2.4.1.16 * spodoptera exigua 174600.0 2 PMID:17456436;PMID:18178495 -2.4.1.161 * entamoeba histolytica 47000.0 1 PMID:2423097 -2.4.1.17 * bos taurus 54000.0 1 PMID:12093618 -2.4.1.17 * cavia porcellus 55000.0 1 PMID:6788550 -2.4.1.17 * homo sapiens 86000.0 28 PMID:11457662;PMID:15039073;PMID:15708967;PMID:17179145;PMID:17620344;PMID:2116769;PMID:2129415;PMID:2506584;PMID:3100939 -2.4.1.17 * macaca mulatta 55000.0 1 PMID:12051676 -2.4.1.17 * mus musculus 51000.0 1 PMID:6428319 -2.4.1.17 * oryctolagus cuniculus 230000.0 2 PMID:6794456;PMID:6799733 -2.4.1.17 * platyrrhini 55000.0 1 PMID:11457662 -2.4.1.17 * rattus norvegicus 318000.0 27 PMID:101208;PMID:111930;PMID:1906977;PMID:2129415;PMID:2506584;PMID:3097500;PMID:3099767;PMID:3408494;PMID:3931633;PMID:402364;PMID:406146;PMID:6416180;PMID:6480579;PMID:6799732;PMID:6806274;PMID:7329300 -2.4.1.17 * sphingomonas paucimobilis 41900.0 3 PMID:11513745 -2.4.1.17 * sus scrofa 52000.0 1 PMID:5106920 -2.4.1.170 * cicer arietinum 50000.0 2 PMID:6458246 -2.4.1.170 * glycine max 46000.0 2 PMID:17565994 -2.4.1.170 * glycyrrhiza echinata 48700.0 1 PMID:14523650 -2.4.1.170 * silene latifolia 54000.0 1 PMID:8370455 -2.4.1.172 * gardenia jasminoides 51000.0 1 * -2.4.1.173 * arabidopsis thaliana 69000.0 1 PMID:9349281 -2.4.1.173 * avena sativa 66000.0 2 PMID:12232266;PMID:9349281 -2.4.1.173 * badhamia polycephala 72000.0 2 PMID:2528379 -2.4.1.173 * candida albicans 171000.0 1 PMID:10224056 -2.4.1.173 * debaryomyces hansenii 61800.0 1 PMID:24056940 -2.4.1.173 * dictyostelium discoideum 114000.0 1 PMID:10224056 -2.4.1.173 * kluyveromyces lactis 55900.0 1 PMID:24056940 -2.4.1.173 * komagataella pastoris 136000.0 1 PMID:10224056 -2.4.1.173 * ogataea angusta 54200.0 1 PMID:24056940 -2.4.1.173 * paris polyphylla var. yunnanensis 110000.0 1 PMID:38851474 -2.4.1.173 * saccharomyces cerevisiae 136000.0 1 PMID:10224056 -2.4.1.173 * sinapis alba 140000.0 1 PMID:497231 -2.4.1.173 * withania somnifera 78000.0 2 PMID:17293176;PMID:17324374 -2.4.1.174 * homo sapiens 95000.0 2 PMID:11788602;PMID:12433924 -2.4.1.175 * bos taurus 160000.0 1 PMID:10491092 -2.4.1.175 * escherichia coli 82000.0 1 PMID:18247116 -2.4.1.175 * homo sapiens 95000.0 2 PMID:11788602;PMID:12433924 -2.4.1.177 * eucalyptus perriniana 51600.0 1 * -2.4.1.177 * fragaria x ananassa 65000.0 2 PMID:16443693 -2.4.1.177 * ipomoea batatas 45000.0 1 PMID:6231280 -2.4.1.178 * triglochin maritima 50000.0 2 PMID:6230992 -2.4.1.18 * anaerobranca gottschalkii 72000.0 1 PMID:16408175 -2.4.1.18 * bergeriella denitrificans 86313.0 1 PMID:10407163 -2.4.1.18 * cyanobacterium sp. 94125.0 6 PMID:25731081 -2.4.1.18 * deinococcus geothermalis 75000.0 1 PMID:19139240 -2.4.1.18 * deinococcus radiodurans 80000.0 1 PMID:19139240 -2.4.1.18 * dickeya chrysanthemi 84000.0 1 PMID:12480526 -2.4.1.18 * escherichia coli 95000.0 3 PMID:407932 -2.4.1.18 * hordeum vulgare 87000.0 1 PMID:12964868 -2.4.1.18 * mycobacterium tuberculosis 86060.0 3 PMID:17005418 -2.4.1.18 * neurospora crassa 80000.0 1 PMID:6226652 -2.4.1.18 * oryctolagus cuniculus 103000.0 6 PMID:5288588;PMID:6225454;PMID:6447599 -2.4.1.18 * oryza sativa 85000.0 3 * -2.4.1.18 * phaseolus vulgaris 100000.0 6 PMID:11440129;PMID:11563966 -2.4.1.18 * rhizomucor miehei 81030.0 3 PMID:24767030 -2.4.1.18 * solanum tuberosum 103000.0 4 PMID:1258;PMID:8954164 -2.4.1.18 * sorghum bicolor 82000.0 1 PMID:12964868 -2.4.1.18 * streptococcus mutans 74000.0 1 PMID:26047289 -2.4.1.18 * synechocystis sp. pcc 6803 90700.0 1 PMID:18756098 -2.4.1.18 * thermococcus kodakarensis 558000.0 2 PMID:16885460 -2.4.1.18 * thermomonospora curvata 84000.0 1 * -2.4.1.18 * vigna radiata 108000.0 1 PMID:19143523 -2.4.1.18 * zea mays 90000.0 2 * -2.4.1.180 * micrococcus luteus 440000.0 3 PMID:21188072 -2.4.1.181 * cinchona succirubra 50000.0 1 * -2.4.1.182 * escherichia coli 360000.0 8 PMID:1495426;PMID:19883124;PMID:2824445;PMID:29371662;PMID:3049593;PMID:3531165 -2.4.1.182 * haemophilus influenzae 42000.0 1 PMID:19883124 -2.4.1.185 * citrus x paradisi 54900.0 1 PMID:2171434 -2.4.1.185 * petunia x hybrida 54400.0 1 PMID:10626374 -2.4.1.186 * homo sapiens 41000.0 2 PMID:22198226 -2.4.1.186 * neurospora crassa 31000.0 1 PMID:8886029 -2.4.1.186 * oryctolagus cuniculus 200000.0 10 PMID:18439421;PMID:18671943;PMID:2970965;PMID:3121316;PMID:9184839 -2.4.1.186 * rattus norvegicus 32000.0 1 * -2.4.1.189 * secale cereale 34500.0 1 * -2.4.1.19 * alkalihalobacillus alcalophilus 85000.0 2 PMID:12449789 -2.4.1.19 * alkalihalobacillus pseudalcaliphilus 71000.0 3 PMID:21894524 -2.4.1.19 * anaerobranca gottschalkii 78000.0 1 PMID:15340782 -2.4.1.19 * bacillus autolyticus 70000.0 2 PMID:12728995 -2.4.1.19 * bacillus cereus 62000.0 1 PMID:25709024 -2.4.1.19 * bacillus licheniformis 74000.0 2 PMID:12449789 -2.4.1.19 * bacillus ohbensis 80000.0 2 * -2.4.1.19 * bacillus sp. (in: firmicutes) 90000.0 16 PMID:22754298;PMID:23129181;PMID:23160123 -2.4.1.19 * bacillus sp. y112 90000.0 1 * -2.4.1.19 * bacillus subtilis 64000.0 1 * -2.4.1.19 * cytobacillus firmus 82000.0 5 PMID:10341434 -2.4.1.19 * evansella caseinilytica 65000.0 1 PMID:34926120 -2.4.1.19 * geobacillus stearothermophilus 75370.0 3 PMID:12449789;PMID:1476442 -2.4.1.19 * gracilibacillus alcaliphilus 85000.0 1 PMID:33222223 -2.4.1.19 * haloferax mediterranei 82000.0 1 PMID:22134680 -2.4.1.19 * heyndrickxia coagulans 65500.0 5 PMID:12449789 -2.4.1.19 * lysinibacillus sphaericus 59000.0 1 * -2.4.1.19 * niallia circulans 200000.0 11 PMID:12449789;PMID:1532314 -2.4.1.19 * paenibacillus campinasensis 70000.0 1 PMID:18478375 -2.4.1.19 * paenibacillus illinoisensis 74352.0 3 PMID:12728995;PMID:23264152 -2.4.1.19 * paenibacillus macerans 145000.0 17 PMID:12449789;PMID:1476442;PMID:20227067;PMID:22754298;PMID:23129181;PMID:23160123;PMID:24037411;PMID:24100578;PMID:39676;PMID:5758537 -2.4.1.19 * paenibacillus pabuli 74300.0 2 PMID:18704190 -2.4.1.19 * paenibacillus sp. 77000.0 1 PMID:17562284 -2.4.1.19 * priestia megaterium 75000.0 4 PMID:18556815 -2.4.1.19 * salimicrobium halophilum 71000.0 2 PMID:12449789 -2.4.1.19 * salipaludibacillus agaradhaerens 89000.0 2 PMID:22949876 -2.4.1.19 * shouchella lehensis 74100.0 1 PMID:25362891 -2.4.1.19 * thermoactinomyces vulgaris 66000.0 1 PMID:12449789 -2.4.1.19 * thermoanaerobacterium thermosulfurigenes 68000.0 1 * -2.4.1.19 * thermococcus kodakarensis 77000.0 1 PMID:11790748 -2.4.1.19 * thermococcus sp. 83000.0 1 PMID:10223990 -2.4.1.19 * uncultured carboxydocella sp. 60000.0 1 PMID:25512632 -2.4.1.190 * secale cereale 37000.0 1 * -2.4.1.191 * secale cereale 29000.0 1 * -2.4.1.192 * avena sativa 62000.0 1 * -2.4.1.194 * lithospermum erythrorhizon 51000.0 2 PMID:1832840 -2.4.1.194 * pinus densiflora 33000.0 1 * -2.4.1.195 * arabidopsis thaliana 57800.0 1 * -2.4.1.195 * brassica juncea 55500.0 2 * -2.4.1.195 * brassica napus 51000.0 2 PMID:12060294;PMID:8373190 -2.4.1.195 * brassica nigra 57000.0 1 PMID:12232212 -2.4.1.195 * brassica oleracea 57600.0 2 PMID:12232212 -2.4.1.195 * brassica rapa subsp. oleifera 55500.0 1 * -2.4.1.195 * tropaeolum majus 50000.0 1 * -2.4.1.196 * petroselinum crispum 46000.0 1 * -2.4.1.198 * aspergillus fumigatus 40000.0 1 PMID:26306635 -2.4.1.2 * gluconobacter oxydans 300000.0 3 PMID:22961394 -2.4.1.20 * acetivibrio thermocellus 150000.0 4 PMID:12153715;PMID:12596851 -2.4.1.20 * caldicellulosiruptor bescii 200000.0 1 PMID:35273293 -2.4.1.20 * cellulomonas gilvus 280000.0 4 PMID:12596851;PMID:6223623 -2.4.1.20 * cellulomonas uda 92000.0 2 * -2.4.1.20 * ruminococcus albus 187000.0 2 PMID:22484959 -2.4.1.20 * thermoclostridium stercorarium 93000.0 1 PMID:9249035 -2.4.1.20 * thermotoga maritima 150000.0 3 PMID:12596851 -2.4.1.20 * thermotoga neapolitana 93000.0 1 PMID:10960102 -2.4.1.201 * gallus gallus 72000.0 4 PMID:10962001;PMID:16428802 -2.4.1.202 * zea mays 50000.0 2 PMID:11851909;PMID:16666853 -2.4.1.203 * phaseolus lunatus 60000.0 2 PMID:16666929 -2.4.1.203 * phaseolus vulgaris 50000.0 1 * -2.4.1.205 * helix pomatia 600000.0 2 PMID:2505854 -2.4.1.207 * actinidia chinensis 36700.0 2 * -2.4.1.207 * actinidia deliciosa 35500.0 8 PMID:9487728 -2.4.1.207 * actinidia eriantha 31800.0 3 * -2.4.1.207 * actinidia hemsleyana 29500.0 1 * -2.4.1.207 * arabidopsis thaliana 36000.0 2 PMID:17674032;PMID:9414546 -2.4.1.207 * betula pendula 38000.0 1 PMID:17462775 -2.4.1.207 * brassica oleracea 32000.0 1 PMID:10975501 -2.4.1.207 * brassica oleracea var. botrytis 33115.0 2 PMID:12826015 -2.4.1.207 * brassica rapa subsp. oleifera 32200.0 1 PMID:16322981 -2.4.1.207 * cicer arietinum 32000.0 1 PMID:16014999;PMID:17075081 -2.4.1.207 * dimocarpus longan 32930.0 3 * -2.4.1.207 * equisetum fluviatile 31000.0 1 PMID:26185964 -2.4.1.207 * hordeum vulgare 35000.0 3 PMID:17329246;PMID:19076217 -2.4.1.207 * malus domestica 36000.0 10 * -2.4.1.207 * nicotiana tabacum 36000.0 2 PMID:11216849 -2.4.1.207 * phaseolus vulgaris 30000.0 1 PMID:17450375 -2.4.1.207 * populus tremula x populus tremuloides 34180.0 4 PMID:16014999;PMID:17075081;PMID:18508770 -2.4.1.207 * sinopodophyllum hexandrum 28000.0 1 PMID:27097640 -2.4.1.207 * solanum lycopersicum 37000.0 4 PMID:16774648;PMID:7632911 -2.4.1.207 * tropaeolum majus 31000.0 3 PMID:20153658;PMID:8374619 -2.4.1.207 * vigna angularis 33000.0 1 PMID:12514239;PMID:1400418 -2.4.1.207 * vigna radiata 33400.0 1 * -2.4.1.207 * vigna radiata var. radiata 32000.0 1 PMID:10975501 -2.4.1.207 * zea mays 59000.0 1 PMID:18316315 -2.4.1.209 * sphagnum fallax 56000.0 1 * -2.4.1.21 * amaranthus cruentus 67000.0 1 * -2.4.1.21 * escherichia coli 92700.0 2 PMID:2288 -2.4.1.21 * hordeum vulgare 98300.0 4 PMID:26858729 -2.4.1.21 * lathyrus oleraceus 77000.0 2 PMID:24186793 -2.4.1.21 * oryza sativa 110000.0 6 PMID:11571184;PMID:1747094 -2.4.1.21 * solanum tuberosum 139000.0 3 PMID:8768372 -2.4.1.21 * sulfolobus acidocaldarius 60000.0 1 PMID:11571184;PMID:1747094 -2.4.1.21 * triticum aestivum 82306.0 1 * -2.4.1.21 * vigna radiata 58000.0 3 PMID:15941320;PMID:19371027 -2.4.1.21 * zea mays 180000.0 5 PMID:26635839;PMID:26940263 -2.4.1.210 * citrus sinensis 58000.0 2 * -2.4.1.210 * citrus unshiu 57500.0 1 PMID:10713266 -2.4.1.211 * bifidobacterium bifidum 140000.0 2 PMID:15933016;PMID:9889079 -2.4.1.211 * bifidobacterium longum 84327.0 1 PMID:15933016 -2.4.1.211 * clostridium perfringens atcc 13124 80000.0 1 PMID:18183385;PMID:19491100 -2.4.1.211 * cutibacterium acnes 83480.0 2 PMID:19132369 -2.4.1.211 * lachnoclostridium phytofermentans 84940.0 4 PMID:18183385;PMID:19491100 -2.4.1.211 * vibrio vulnificus 83580.0 1 PMID:18723650 -2.4.1.212 * homo sapiens 66000.0 4 PMID:17493932;PMID:9555098 -2.4.1.212 * mus musculus 52000.0 2 PMID:8077292;PMID:8798545 -2.4.1.212 * streptococcus dysgalactiae subsp. equisimilis 49000.0 3 PMID:15248781;PMID:9405467;PMID:9933623 -2.4.1.212 * streptococcus pyogenes 48000.0 3 PMID:12512859;PMID:8049203;PMID:8366070;PMID:9405467;PMID:9933623 -2.4.1.214 * anopheles gambiae 61000.0 2 PMID:26617287 -2.4.1.214 * apis mellifera 53000.0 1 PMID:17029591 -2.4.1.214 * arabidopsis thaliana 56210.0 3 PMID:11420147;PMID:21515584 -2.4.1.214 * caenorhabditis elegans 51000.0 2 PMID:17369288;PMID:23754284 -2.4.1.214 * homo sapiens 55000.0 2 PMID:11555615 -2.4.1.214 * mus musculus 56700.0 1 PMID:23986452 -2.4.1.214 * vigna radiata 65000.0 4 PMID:10419500;PMID:8748155 -2.4.1.215 * oryza sativa japonica group 55400.0 3 PMID:22811434 -2.4.1.215 * zea mays 52000.0 2 PMID:11331778;PMID:12644686 -2.4.1.216 * lactococcus lactis 94000.0 1 PMID:11553642 -2.4.1.216 * lactococcus lactis ssp. lactis 184000.0 3 PMID:28537141 -2.4.1.217 * dehalococcoides mccartyi 78000.0 2 PMID:15205409 -2.4.1.217 * palaeococcus ferrophilus 44300.0 2 PMID:16332790 -2.4.1.217 * rhodothermus marinus 48795.0 2 PMID:14701859 -2.4.1.217 * rubrobacter xylanophilus 95000.0 2 PMID:18678952 -2.4.1.217 * thermus thermophilus 44000.0 2 PMID:12788726;PMID:19851010 -2.4.1.218 * rauvolfia serpentina 52000.0 2 PMID:10680170;PMID:11505382 -2.4.1.219 * rauvolfia serpentina 66600.0 2 PMID:10234858 -2.4.1.22 * bos taurus 60000.0 4 PMID:15678424;PMID:819261 -2.4.1.22 * homo sapiens 75000.0 1 * -2.4.1.220 * persicaria tinctoria 53000.0 3 PMID:10795317;PMID:30189417 -2.4.1.220 * strobilanthes cusia 60000.0 1 PMID:10680172 -2.4.1.221 * cricetulus griseus 44000.0 1 PMID:9525914 -2.4.1.221 * mus musculus 56700.0 1 PMID:23986452 -2.4.1.221 * plasmodium falciparum 59000.0 1 PMID:28916755 -2.4.1.222 * homo sapiens 53000.0 2 PMID:21868414 -2.4.1.222 * mus musculus 43600.0 3 PMID:18706457 -2.4.1.224 * bos taurus 90000.0 5 PMID:11256613;PMID:9756849 -2.4.1.224 * caenorhabditis elegans 130000.0 2 PMID:11121397 -2.4.1.224 * cricetinae 91000.0 2 PMID:9620772 -2.4.1.224 * escherichia coli 27000.0 1 PMID:17014088 -2.4.1.224 * homo sapiens 160000.0 3 PMID:12907669;PMID:18216313 -2.4.1.224 * mus musculus 90000.0 2 PMID:11256613 -2.4.1.225 * bos taurus 81900.0 2 PMID:9756849 -2.4.1.225 * homo sapiens 160000.0 2 PMID:12907669 -2.4.1.227 * escherichia coli 76000.0 7 PMID:12813070;PMID:12851929;PMID:1649817;PMID:17640276;PMID:17692452;PMID:18081839 -2.4.1.228 * homo sapiens 37500.0 1 PMID:26773500 -2.4.1.228 * rattus norvegicus 90000.0 3 PMID:3921539 -2.4.1.229 * dictyostelium sp. 51000.0 2 PMID:10593934;PMID:11886837 -2.4.1.230 * caldicellulosiruptor saccharolyticus 170000.0 2 PMID:21670511 -2.4.1.230 * pyrococcus sp. 80000.0 1 PMID:24391053 -2.4.1.230 * thermoanaerobacter brockii 83000.0 1 * -2.4.1.231 * agaricus bisporus 240000.0 2 PMID:9813313 -2.4.1.231 * grifola frondosa 120000.0 2 PMID:9797287 -2.4.1.231 * lentinus sajor-caju 88000.0 1 PMID:12880768 -2.4.1.231 * pleurotus ostreatus 120000.0 4 PMID:17222933 -2.4.1.231 * pleurotus pulmonarius 82028.0 1 PMID:37780800 -2.4.1.231 * schizophyllum commune 61000.0 3 PMID:10393097;PMID:9872418 -2.4.1.234 * petunia x hybrida 50000.0 3 PMID:10567367 -2.4.1.234 * vigna mungo 43000.0 1 * -2.4.1.236 * citrus maxima 52000.0 3 PMID:1939145;PMID:26433966 -2.4.1.237 * beta vulgaris 54390.0 2 PMID:16876834 -2.4.1.237 * euonymus alatus 48000.0 1 * -2.4.1.237 * paederia scandens 43000.0 1 * -2.4.1.238 * gentiana triflora 55000.0 2 PMID:12857844 -2.4.1.24 * aspergillus niger 109000.0 2 * -2.4.1.242 * aegilops longissima 59200.0 1 PMID:9126669 -2.4.1.242 * aegilops searsii 59100.0 1 PMID:9126669 -2.4.1.242 * aegilops speltoides 59000.0 1 PMID:9126669 -2.4.1.242 * aegilops tauschii 59200.0 1 PMID:9126669 -2.4.1.242 * gracilaria tenuistipitata 580000.0 2 PMID:10467041 -2.4.1.242 * ipomoea batatas 60000.0 1 PMID:17622537 -2.4.1.242 * lathyrus oleraceus 77000.0 3 PMID:12232029;PMID:24197382 -2.4.1.242 * musa acuminata 83600.0 7 PMID:24505384 -2.4.1.242 * oryza sativa 60000.0 2 PMID:18422889;PMID:19760367;PMID:22878205 -2.4.1.242 * solanum tuberosum 60000.0 1 PMID:18422889;PMID:19760367 -2.4.1.242 * triticum aestivum 309000.0 4 PMID:9126669;PMID:9765530 -2.4.1.242 * triticum monococcum 59500.0 3 PMID:9126669;PMID:9951718 -2.4.1.242 * triticum turgidum 60000.0 1 PMID:9126669 -2.4.1.242 * triticum urartu 59400.0 1 PMID:9126669 -2.4.1.242 * vigna radiata 58000.0 1 PMID:19371027 -2.4.1.242 * zea mays 58000.0 2 PMID:18653693 -2.4.1.243 * agave tequilana 70700.0 2 PMID:22558253 -2.4.1.243 * allium cepa 66000.0 3 PMID:15720662 -2.4.1.243 * asparagus officinalis 69000.0 2 PMID:15720693 -2.4.1.245 * pyrococcus horikoshii 49871.0 2 PMID:15737605 -2.4.1.245 * rubrobacter xylanophilus 46700.0 1 PMID:18835983 -2.4.1.245 * thermococcus litoralis 104000.0 3 PMID:15364950 -2.4.1.245 * thermoproteus tenax 100000.0 3 PMID:18483808 -2.4.1.245 * thermotoga maritima 47000.0 1 * -2.4.1.247 * lachnoclostridium phytofermentans 84230.0 2 PMID:19491100 -2.4.1.247 * opitutus terrae 84847.0 2 * -2.4.1.248 * niallia circulans 184000.0 4 PMID:17090949;PMID:22075636 -2.4.1.248 * thermoanaerobacter thermocopriae 175269.0 3 PMID:30927134;PMID:31838796 -2.4.1.249 * clitoria ternatea 58000.0 3 PMID:17668234 -2.4.1.25 * arabidopsis thaliana 123000.0 2 * -2.4.1.25 * bacillus sp. (in: firmicutes) 80000.0 1 PMID:4972097 -2.4.1.25 * chlamydomonas reinhardtii 62000.0 1 PMID:10444082 -2.4.1.25 * corynebacterium glutamicum 81000.0 2 PMID:22865069;PMID:23989149 -2.4.1.25 * culex quinquefasciatus 120000.0 1 PMID:29229337 -2.4.1.25 * escherichia coli 370000.0 6 PMID:26139606;PMID:791642 -2.4.1.25 * lathyrus oleraceus 98000.0 2 PMID:16666985 -2.4.1.25 * manihot esculenta 117000.0 2 * -2.4.1.25 * oryctolagus cuniculus 270000.0 5 PMID:1122910 -2.4.1.25 * pyrococcus sp. 76690.0 1 * -2.4.1.25 * rattus norvegicus 160000.0 1 PMID:15180797 -2.4.1.25 * saccharolobus solfataricus 83000.0 1 PMID:17485831 -2.4.1.25 * saccharomyces cerevisiae 174900.0 2 PMID:10873545 -2.4.1.25 * solanum tuberosum 65000.0 4 PMID:7678257 -2.4.1.25 * stutzerimonas stutzeri 115000.0 6 PMID:758954 -2.4.1.25 * sus scrofa 170000.0 1 PMID:16798776 -2.4.1.25 * synechocystis sp. 57000.0 1 PMID:19576307 -2.4.1.25 * thermococcus litoralis 168000.0 6 PMID:10348846;PMID:10471815;PMID:12618437;PMID:9310375 -2.4.1.25 * thermotoga maritima 56000.0 3 PMID:1628664 -2.4.1.25 * thermotoga neapolitana 51900.0 1 * -2.4.1.25 * thermus aquaticus 57969.0 2 PMID:10049841 -2.4.1.25 * thermus brockianus 57220.0 1 * -2.4.1.25 * thermus thermophilus 59337.0 2 PMID:17407266 -2.4.1.25 * triticum aestivum 54000.0 1 PMID:16333636 -2.4.1.251 * xanthomonas campestris 36000.0 1 PMID:21367879 -2.4.1.252 * xylella fastidiosa 45000.0 1 PMID:14766234 -2.4.1.253 * scutellaria baicalensis 110000.0 2 PMID:10724177 -2.4.1.254 * bellis perennis 54000.0 3 PMID:15509561 -2.4.1.255 * bos taurus 110000.0 3 PMID:11148210;PMID:22496241;PMID:9083067 -2.4.1.255 * homo sapiens 116000.0 10 PMID:10753899;PMID:16434389;PMID:16714295;PMID:19957065;PMID:22496241;PMID:9083067 -2.4.1.255 * oryctolagus cuniculus 110000.0 2 PMID:9083068 -2.4.1.255 * rattus norvegicus 340000.0 17 PMID:10580430;PMID:11339805;PMID:11700029;PMID:12618343;PMID:1533623;PMID:16714295;PMID:22496241;PMID:22928023;PMID:9083067 -2.4.1.258 * komagataella pastoris 53030.0 2 PMID:15033937 -2.4.1.258 * saccharomyces cerevisiae 52861.0 3 PMID:11308030;PMID:8842708 -2.4.1.258 * trypanosoma brucei 46701.0 2 PMID:18263655 -2.4.1.26 * tequatrovirus t4 46651.0 1 PMID:4018026 -2.4.1.262 * glycine max 66000.0 2 PMID:12172845 -2.4.1.263 * vigna angularis 80000.0 1 PMID:12114582 -2.4.1.264 * xanthomonas campestris 44000.0 1 PMID:14736729 -2.4.1.265 * saccharomyces cerevisiae 67390.0 2 PMID:8016100 -2.4.1.266 * methanococcoides burtonii 43000.0 1 PMID:16428406 -2.4.1.266 * mycobacterium tuberculosis variant bovis 101100.0 2 PMID:18221489 -2.4.1.266 * mycolicibacterium smegmatis 106900.0 2 PMID:18221489 -2.4.1.266 * persephonella marina 105400.0 2 PMID:17189358 -2.4.1.266 * petrotoga mobilis 80000.0 2 PMID:20061481 -2.4.1.266 * rhodopirellula baltica 218600.0 2 PMID:23921581 -2.4.1.268 * persephonella marina 210000.0 3 PMID:17369297 -2.4.1.268 * petrotoga mobilis 170000.0 2 PMID:20061481 -2.4.1.269 * rhodothermus marinus 122000.0 3 PMID:10585410 -2.4.1.269 * selaginella moellendorffii 217200.0 2 PMID:23179444 -2.4.1.270 * petrotoga mobilis 59000.0 2 PMID:20061481 -2.4.1.270 * rhodopirellula baltica 121900.0 2 PMID:23921581 -2.4.1.271 * carthamus tinctorius 49400.0 1 PMID:26840283 -2.4.1.271 * crocus sativus 55000.0 6 PMID:15605174;PMID:26840283;PMID:38838622 -2.4.1.271 * gardenia jasminoides 49400.0 1 PMID:26840283 -2.4.1.272 * glycine max 60600.0 2 PMID:20350545;PMID:32689796 -2.4.1.273 * glycine max 53518.0 1 PMID:20350545 -2.4.1.274 * rattus norvegicus 61000.0 2 PMID:9593693 -2.4.1.276 * paracoccus haeundaensis 46798.0 2 PMID:20075616 -2.4.1.276 * pseudescherichia vulneris 45000.0 1 PMID:1409639 -2.4.1.279 * lachnoclostridium phytofermentans 87170.0 1 PMID:21808968 -2.4.1.280 * vibrio furnissii 89670.0 1 PMID:10913116 -2.4.1.280 * vibrio proteolyticus 150000.0 3 PMID:13678418 -2.4.1.281 * bacteroides fragilis 43890.0 1 PMID:21539815 -2.4.1.281 * rhodothermus marinus 222000.0 2 PMID:25036679 -2.4.1.281 * ruminococcus albus 209000.0 6 PMID:23093406 -2.4.1.282 * lachnoclostridium phytofermentans 88000.0 2 PMID:22277537 -2.4.1.287 * mycobacterium tuberculosis 33863.0 1 PMID:16952951 -2.4.1.288 * mycobacterium tuberculosis 73500.0 2 PMID:16952951;PMID:18423586 -2.4.1.289 * campylobacter jejuni 43000.0 1 PMID:16186480 -2.4.1.290 * campylobacter jejuni 43000.0 1 PMID:16186480 -2.4.1.291 * campylobacter jejuni 41000.0 1 PMID:16186480 -2.4.1.292 * campylobacter jejuni 41000.0 1 PMID:16186480 -2.4.1.293 * campylobacter jejuni 36000.0 1 PMID:16186480 -2.4.1.294 * camellia sinensis var. sinensis 55000.0 2 PMID:34217130 -2.4.1.296 * petunia x hybrida 52163.0 2 PMID:11905966;PMID:24258583 -2.4.1.297 * erythrina crista-galli 82000.0 1 * -2.4.1.298 * dahlia pinnata 53000.0 1 * -2.4.1.298 * glandularia x hybrida 51347.0 1 PMID:10066805 -2.4.1.298 * perilla frutescens 50973.0 2 PMID:10066805 -2.4.1.298 * vitis amurensis 70000.0 2 PMID:26159788 -2.4.1.298 * vitis vinifera 55400.0 1 * -2.4.1.299 * dianthus caryophyllus 55000.0 1 PMID:20971893 -2.4.1.30 * anaerolinea thermophila 133000.0 1 PMID:38659290 -2.4.1.302 * streptomyces niveus 40000.0 1 PMID:12680772 -2.4.1.304 * shigella boydii 30000.0 1 PMID:21057010 -2.4.1.305 * escherichia coli 55400.0 2 PMID:18487334 -2.4.1.306 * escherichia coli 38148.0 2 PMID:16630548 -2.4.1.31 * euglena gracilis 200000.0 2 PMID:8346926 -2.4.1.31 * paenibacillus sp. 200000.0 2 PMID:22313784 -2.4.1.31 * paenibacillus sp. ym-1 240000.0 1 PMID:29856496 -2.4.1.310 * amycolatopsis orientalis 44000.0 1 PMID:11294642 -2.4.1.313 * homo sapiens 55000.0 1 PMID:14724282 -2.4.1.314 * panax notoginseng 36000.0 1 * -2.4.1.315 * bacillus subtilis 43600.0 1 PMID:9720862 -2.4.1.315 * staphylococcus aureus 44700.0 2 PMID:10848996 -2.4.1.316 * streptomyces fradiae 48640.0 1 PMID:9031628 -2.4.1.317 * streptomyces fradiae 46635.0 1 PMID:9651492 -2.4.1.318 * streptomyces fradiae 30120.0 1 PMID:10658660 -2.4.1.319 * ruminococcus albus 209000.0 4 PMID:23093406 -2.4.1.320 * bacteroides thetaiotaomicron 147000.0 6 PMID:23943617 -2.4.1.321 * neurospora crassa 171000.0 5 PMID:24055472 -2.4.1.321 * saccharophagus degradans 147000.0 2 PMID:26041776 -2.4.1.321 * xanthomonas campestris 179000.0 3 PMID:24055472 -2.4.1.321 * xanthomonas campestris pv. campestris 179000.0 3 PMID:24055472 -2.4.1.322 * amycolatopsis orientalis 44000.0 2 PMID:11294642;PMID:15122882 -2.4.1.324 * picrorhiza kurrooa 55000.0 1 PMID:24066073 -2.4.1.325 * escherichia coli 41500.0 1 PMID:11673418 -2.4.1.327 * streptomyces galilaeus 65000.0 3 PMID:15078101 -2.4.1.328 * saccharopolyspora erythraea 45500.0 1 PMID:9353926 -2.4.1.329 * mediterraneibacter gnavus 55000.0 1 PMID:30913025 -2.4.1.329 * thermoanaerobacterium thermosaccharolyticum 56700.0 2 PMID:24599311 -2.4.1.330 * gardenia jasminoides 49800.0 1 PMID:22569263 -2.4.1.332 * salisediminibacterium selenitireducens 174000.0 3 PMID:24466148 -2.4.1.333 * listeria innocua 122900.0 2 PMID:24647662 -2.4.1.335 * methanococcus voltae 37328.0 1 PMID:23624439 -2.4.1.337 * acholeplasma laidlawii 40000.0 2 PMID:8995384 -2.4.1.338 * streptomyces hygroscopicus 56000.0 3 PMID:16632251;PMID:17459612;PMID:23340099 -2.4.1.339 * listeria innocua 88000.0 2 PMID:26632508 -2.4.1.34 * agrobacterium sp. 420000.0 4 PMID:12851288 -2.4.1.34 * arabidopsis thaliana 220000.0 1 PMID:15842618 -2.4.1.34 * arachis hypogaea 48000.0 1 PMID:1329666 -2.4.1.34 * aspergillus nidulans 229000.0 1 PMID:8755864 -2.4.1.34 * metarhizium acridum 221700.0 1 PMID:21562714 -2.4.1.34 * neurospora crassa 223000.0 4 PMID:12732946;PMID:26150287;PMID:7937796;PMID:7947947 -2.4.1.34 * nicotiana alata 220000.0 2 PMID:18462191 -2.4.1.34 * paracoccidioides brasiliensis 57000.0 1 PMID:20943190 -2.4.1.34 * phaseolus vulgaris 55000.0 1 PMID:9362565 -2.4.1.34 * phytophthora sojae 108000.0 1 PMID:9744792 -2.4.1.34 * saccharomyces cerevisiae 200000.0 1 PMID:7649185 -2.4.1.34 * schizosaccharomyces pombe 225000.0 1 PMID:15615781 -2.4.1.340 * thermoanaerobacter sp. 50000.0 3 PMID:25500577 -2.4.1.341 * escherichia coli 30000.0 1 PMID:26703456 -2.4.1.343 * escherichia coli 43948.0 1 PMID:27196310 -2.4.1.344 * homo sapiens 320000.0 3 PMID:2136354;PMID:8690714 -2.4.1.344 * sus scrofa 55000.0 1 PMID:7592879 -2.4.1.345 * mycobacterium tuberculosis 42000.0 2 PMID:15939292 -2.4.1.345 * mycolicibacterium smegmatis 43300.0 2 PMID:12068013;PMID:16511084 -2.4.1.346 * mycobacterium tuberculosis 41200.0 1 PMID:10531370 -2.4.1.347 * rubrobacter xylanophilus 53900.0 1 PMID:18835983 -2.4.1.35 * carica papaya 56000.0 2 * -2.4.1.35 * legionella pneumophila 60000.0 1 PMID:12496164 -2.4.1.35 * vigna radiata var. radiata 62000.0 1 PMID:16658986 -2.4.1.355 * staphylococcus aureus 200000.0 1 PMID:27973583 -2.4.1.357 * malus domestica 70700.0 2 PMID:27731384 -2.4.1.36 * streptomyces venezuelae 109000.0 1 PMID:27903647 -2.4.1.360 * fagopyrum esculentum 50430.0 3 PMID:25142187 -2.4.1.360 * glycine max 52520.0 1 PMID:25979175 -2.4.1.360 * oryza sativa indica group 55250.0 2 PMID:19411659 -2.4.1.365 * salinispora tropica 62000.0 1 PMID:40005208 -2.4.1.37 * homo sapiens 80000.0 2 PMID:618876 -2.4.1.371 * escherichia coli 137000.0 3 PMID:22875852;PMID:22989876;PMID:25422321 -2.4.1.373 * apilactobacillus kunkeei 300000.0 1 PMID:36906201 -2.4.1.375 * linum usitatissimum 500000.0 1 PMID:11506367 -2.4.1.38 * bos taurus 59000.0 5 PMID:203458;PMID:2502398;PMID:35107;PMID:3932335 -2.4.1.38 * homo sapiens 106000.0 8 PMID:19032152;PMID:23583406;PMID:414742;PMID:8370673;PMID:8444150;PMID:8706738 -2.4.1.38 * leishmania donovani 29000.0 1 PMID:18197475 -2.4.1.38 * mus musculus 44420.0 2 PMID:3134348 -2.4.1.38 * rattus norvegicus 440000.0 3 PMID:1639751;PMID:821479;PMID:8375379 -2.4.1.38 * sus scrofa 74000.0 3 PMID:113033;PMID:990260 -2.4.1.385 * withania somnifera 52000.0 1 PMID:17704015 -2.4.1.390 * limosilactobacillus fermentum 110000.0 2 PMID:39017685;PMID:39198197 -2.4.1.391 * ignavibacterium album 141000.0 1 PMID:35065074 -2.4.1.392 * paenibacillus borealis 87000.0 1 PMID:35947916 -2.4.1.394 * azotobacter chroococcum 90000.0 2 PMID:26868718 -2.4.1.394 * exiguobacterium artemiae 99000.0 1 PMID:26590275 -2.4.1.394 * limosilactobacillus reuteri 180000.0 4 PMID:22361861 -2.4.1.395 * limosilactobacillus reuteri 99000.0 1 PMID:35129339 -2.4.1.396 * weissella confusa 100000.0 1 PMID:38231152 -2.4.1.397 * thermoanaerobacter italicus 60600.0 1 PMID:38300345 -2.4.1.4 * bifidobacterium thermophilum 70000.0 1 PMID:35080876 -2.4.1.4 * calidithermus timidus 264950.0 2 PMID:31389242 -2.4.1.4 * cellulomonas carbonis 71934.0 1 PMID:28240031 -2.4.1.4 * deinococcus cellulosilyticus 226600.0 2 PMID:38688341 -2.4.1.4 * deinococcus geothermalis 73214.0 4 PMID:22314516;PMID:31906359 -2.4.1.4 * deinococcus radiopugnans 152100.0 3 * -2.4.1.4 * methylobacillus flagellatus 74560.0 1 PMID:24733530 -2.4.1.4 * methylotuvimicrobium alcaliphilum 32700.0 1 PMID:25577257 -2.4.1.4 * neisseria polysaccharea 85000.0 3 PMID:24893853;PMID:9882648 -2.4.1.4 * neisseria subflava 72000.0 1 PMID:29253543 -2.4.1.4 * pseudarthrobacter chlorophenolicus 72000.0 2 PMID:22814500 -2.4.1.40 * homo sapiens 100000.0 4 PMID:2104827;PMID:2121135;PMID:2341371;PMID:618875 -2.4.1.40 * sus scrofa 100000.0 2 PMID:14962 -2.4.1.41 * biomphalaria glabrata 65000.0 1 PMID:23877648 -2.4.1.41 * bos taurus 200000.0 4 PMID:3082881;PMID:7606161 -2.4.1.41 * homo sapiens 87000.0 7 PMID:17596962;PMID:7592619 -2.4.1.41 * mus musculus 71500.0 4 PMID:19880513;PMID:3082881 -2.4.1.41 * ovis sp. 100000.0 1 PMID:7592620 -2.4.1.41 * rattus norvegicus 56000.0 2 PMID:6809738 -2.4.1.41 * sus scrofa 100000.0 3 PMID:1618775;PMID:7592620;PMID:9746219 -2.4.1.41 * xenopus laevis 75000.0 2 PMID:25447273 -2.4.1.43 * arabidopsis thaliana 250000.0 3 PMID:22135470;PMID:34908202 -2.4.1.46 * arabidopsis thaliana 52860.0 7 PMID:11171188;PMID:19179086;PMID:25002864 -2.4.1.46 * cucumis sp. 47000.0 1 PMID:19179086 -2.4.1.46 * oryza sativa 40000.0 1 PMID:24843077 -2.4.1.46 * spinacia oleracea 97000.0 4 PMID:10518794;PMID:24194148 -2.4.1.47 * rattus norvegicus 500000.0 7 PMID:1260034;PMID:12925779;PMID:6792465;PMID:8521863;PMID:8661124 -2.4.1.49 * acetivibrio thermocellus 218000.0 6 PMID:20678539;PMID:21630044 -2.4.1.49 * thermoclostridium stercorarium 91000.0 2 PMID:21344678;PMID:9249035 -2.4.1.5 * escherichia coli 170000.0 1 PMID:19062655 -2.4.1.5 * latilactobacillus curvatus 183630.0 1 PMID:23498178 -2.4.1.5 * leuconostoc citreum 240000.0 6 PMID:21229247;PMID:21229378;PMID:22534298;PMID:39059525 -2.4.1.5 * leuconostoc lactis 165000.0 1 PMID:19853426 -2.4.1.5 * leuconostoc mesenteroides 240000.0 18 PMID:17892930;PMID:18048914;PMID:18207273;PMID:18414801;PMID:23044124;PMID:238637;PMID:29101023;PMID:34649690;PMID:4133613;PMID:6156708;PMID:8441 -2.4.1.5 * limosilactobacillus ingluviei 117400.0 2 PMID:31650841 -2.4.1.5 * pediococcus pentosaceus 224000.0 2 PMID:25434098 -2.4.1.5 * streptococcus mutans 170000.0 4 PMID:18414801;PMID:37158310;PMID:4133613;PMID:4821094 -2.4.1.5 * streptococcus sanguinis 100000.0 1 PMID:39674 -2.4.1.5 * weissella cibaria 180000.0 3 PMID:19222580;PMID:23464916 -2.4.1.5 * weissella confusa 180000.0 2 PMID:25603169;PMID:26861959 -2.4.1.50 * gallus gallus 450000.0 3 PMID:938472 -2.4.1.50 * homo sapiens 85000.0 2 PMID:18298658;PMID:18834968 -2.4.1.54 * micrococcus luteus 30700.0 1 PMID:17072001 -2.4.1.58 * salmonella enterica subsp. enterica serovar typhimurium 20000.0 1 PMID:4553445 -2.4.1.62 * gallus gallus 65000.0 2 PMID:8748162 -2.4.1.62 * mus musculus 43000.0 1 PMID:10502288;PMID:10905635 -2.4.1.62 * rattus norvegicus 64000.0 2 PMID:8521863;PMID:9748263 -2.4.1.64 * caldanaerobacter subterraneus subsp. pacificus 90487.0 1 PMID:21803886 -2.4.1.64 * euglena gracilis 344000.0 1 PMID:4623846 -2.4.1.64 * kocuria varians 580000.0 2 * -2.4.1.64 * salisediminibacterium selenitireducens 170000.0 3 PMID:24021648 -2.4.1.64 * thermoanaerobacter brockii 190000.0 2 * -2.4.1.64 * thermoanaerobacter brockii subsp. brockii 180000.0 3 PMID:20383018 -2.4.1.65 * helicobacter pylori 64500.0 5 PMID:12676935;PMID:16000696;PMID:16407247 -2.4.1.65 * homo sapiens 53000.0 5 PMID:14718375;PMID:1520296;PMID:7287719;PMID:9703429 -2.4.1.65 * pan troglodytes 43233.0 1 PMID:9368041 -2.4.1.65 * rattus norvegicus 68780.0 1 PMID:8729003 -2.4.1.66 * bos taurus 72000.0 1 PMID:241697 -2.4.1.66 * gallus gallus 70000.0 3 PMID:743222;PMID:817743;PMID:942695;PMID:986940 -2.4.1.66 * homo sapiens 180000.0 5 PMID:11956192;PMID:12475640;PMID:18298658;PMID:18834968;PMID:26380979 -2.4.1.66 * mus musculus 96000.0 1 PMID:22573318 -2.4.1.66 * takifugu rubripes 84558.0 1 PMID:23954882 -2.4.1.67 * arabidopsis thaliana 100000.0 3 PMID:26483807 -2.4.1.67 * lathyrus oleraceus 95000.0 1 PMID:11675396 -2.4.1.67 * lens culinaris 99000.0 2 PMID:10334866 -2.4.1.67 * vigna angularis 110000.0 4 PMID:10652123;PMID:9576785 -2.4.1.68 * bombyx mori 120000.0 2 PMID:24973708 -2.4.1.68 * cricetulus griseus 44000.0 1 PMID:9525914 -2.4.1.68 * homo sapiens 62000.0 7 PMID:10580126;PMID:16344263;PMID:22982178;PMID:9133635;PMID:9870354 -2.4.1.68 * sus scrofa 58000.0 1 PMID:10580126;PMID:8910378 -2.4.1.69 * arabidopsis thaliana 61000.0 3 PMID:20194500 -2.4.1.69 * caenorhabditis elegans 175000.0 4 PMID:18252778 -2.4.1.69 * escherichia coli 120000.0 8 PMID:18078329;PMID:18842005;PMID:20801103;PMID:24249735 -2.4.1.69 * homo sapiens 320000.0 6 PMID:1733969;PMID:2136354;PMID:2394712;PMID:8690714 -2.4.1.69 * sus scrofa 80000.0 2 PMID:6246105;PMID:7592879 -2.4.1.7 * bifidobacterium adolescentis 129000.0 7 PMID:14740189;PMID:14756551 -2.4.1.7 * bifidobacterium dentium 124430.0 2 * -2.4.1.7 * bifidobacterium longum 56510.0 2 PMID:14514069;PMID:29380264 -2.4.1.7 * leuconostoc mesenteroides 60600.0 17 PMID:1368718;PMID:17215056;PMID:17233628;PMID:18038113;PMID:31978533;PMID:9063981 -2.4.1.7 * pseudobutyrivibrio ruminis 52000.0 1 PMID:19320946 -2.4.1.7 * roseateles saccharophilus 100000.0 4 PMID:4381552 -2.4.1.7 * streptococcus mutans 55700.0 2 * -2.4.1.7 * thermoanaerobacterium thermosaccharolyticum 56000.0 1 PMID:31978533 -2.4.1.7 * thermobacillus sp. zcth02-b1 55800.0 1 PMID:31470069 -2.4.1.74 * dictyostelium discoideum 200000.0 1 PMID:15558817 -2.4.1.79 * canis lupus familiaris 120000.0 1 PMID:6425294 -2.4.1.79 * homo sapiens 39511.0 1 PMID:10993897 -2.4.1.8 * bacillus sp. (in: firmicutes) 170000.0 2 PMID:11826959;PMID:12596853 -2.4.1.8 * bacillus sp. ahu2001 193000.0 2 PMID:31262243 -2.4.1.8 * emticicia oligotrophica 89000.0 1 * -2.4.1.8 * lactobacillus acidophilus 88000.0 1 PMID:19919544 -2.4.1.8 * levilactobacillus brevis 196000.0 3 PMID:8992944;PMID:9343859 -2.4.1.8 * paenibacillus sp. 180000.0 3 * -2.4.1.8 * propionibacterium freudenreichii 240000.0 2 * -2.4.1.8 * salisediminibacterium selenitireducens 90660.0 2 PMID:22940176 -2.4.1.80 * homo sapiens 448530.0 2 PMID:10563309;PMID:8643456;PMID:9867864 -2.4.1.80 * rattus norvegicus 66000.0 3 PMID:9695839;PMID:9867864 -2.4.1.81 * arabidopsis thaliana 54800.0 1 PMID:16794327 -2.4.1.81 * marchantia paleacea 76510.0 2 PMID:34166976 -2.4.1.81 * petroselinum crispum 50000.0 1 PMID:5058406 -2.4.1.82 * arabidopsis thaliana 100000.0 2 PMID:26483807 -2.4.1.82 * cucumis sativus 79000.0 1 PMID:22985990 -2.4.1.82 * lathyrus oleraceus 88700.0 1 PMID:12244450 -2.4.1.82 * vicia faba 100000.0 2 PMID:4774118 -2.4.1.83 * bos taurus 33000.0 1 PMID:19214747 -2.4.1.83 * haloferax volcanii 85000.0 1 PMID:21338478 -2.4.1.83 * mus musculus 30000.0 1 PMID:1606967;PMID:2659345 -2.4.1.83 * pyrococcus horikoshii 41010.0 1 PMID:18563288 -2.4.1.83 * saccharomyces cerevisiae 30000.0 1 PMID:1606967;PMID:2659345 -2.4.1.83 * thermoplasma acidophilum 42000.0 1 PMID:9023542 -2.4.1.85 * sorghum bicolor 52900.0 1 PMID:10585420 -2.4.1.87 * bos taurus 43000.0 1 PMID:3932335 -2.4.1.87 * homo sapiens 34483.0 1 PMID:18509110 -2.4.1.87 * mus musculus 80000.0 1 PMID:3084477 -2.4.1.87 * streptococcus pneumoniae 39000.0 2 PMID:22742596 -2.4.1.88 * canis lupus familiaris 120000.0 3 PMID:6809754 -2.4.1.9 * aspergillus oryzae 116300.0 1 PMID:18612595 -2.4.1.9 * aureobasidium pullulans 570000.0 1 PMID:18394739 -2.4.1.9 * lactiplantibacillus plantarum 102460.0 1 PMID:38788653 -2.4.1.9 * lactobacillus gasseri 65000.0 1 PMID:29169948 -2.4.1.9 * leuconostoc citreum 165000.0 2 PMID:39214229 -2.4.1.9 * neobacillus drentensis 174000.0 1 PMID:37491698 -2.4.1.90 * bos taurus 59000.0 5 PMID:203458;PMID:2502398;PMID:35107;PMID:3932335 -2.4.1.90 * homo sapiens 106000.0 7 PMID:30352055;PMID:414742;PMID:8370673;PMID:8444150;PMID:8706738 -2.4.1.90 * mus musculus 44420.0 2 PMID:3134348 -2.4.1.90 * rattus norvegicus 440000.0 3 PMID:1639751;PMID:821479;PMID:8375379 -2.4.1.90 * sus scrofa 74000.0 3 PMID:113033;PMID:990260 -2.4.1.90 * trichosurus vulpecula 66000.0 1 PMID:18402760 -2.4.1.91 * brassica oleracea 59000.0 1 PMID:16668021 -2.4.1.91 * citrus x paradisi 51200.0 2 PMID:19733370 -2.4.1.91 * euonymus alatus 48000.0 1 * -2.4.1.91 * glycine max 49800.0 2 PMID:20621794 -2.4.1.91 * hippeastrum sp. 49000.0 2 * -2.4.1.91 * litchi chinensis 52000.0 1 PMID:22447536 -2.4.1.91 * marchantia emarginata 75990.0 4 PMID:34166976 -2.4.1.91 * oryza sativa 66000.0 1 PMID:18047780 -2.4.1.91 * paederia scandens 43000.0 1 * -2.4.1.91 * prunus yedoensis 51000.0 1 * -2.4.1.91 * solanum tuberosum 49900.0 1 PMID:20358295 -2.4.1.91 * triticum aestivum 53000.0 1 PMID:12943758 -2.4.1.91 * tulipa hybrid cultivar 40000.0 1 * -2.4.1.91 * vigna mungo 43000.0 1 * -2.4.1.91 * vitis amurensis 50190.0 1 * -2.4.1.92 * mus musculus 120000.0 3 PMID:14579597;PMID:8245020 -2.4.1.92 * rattus norvegicus 120000.0 2 PMID:3109491 -2.4.1.96 * poterioochromonas malhamensis 70000.0 2 * -2.4.1.97 * ochromonas danica 250000.0 7 PMID:24018693 -2.4.1.99 * agave tequilana 75000.0 1 * -2.4.1.99 * agave vera cruz 62000.0 1 PMID:1010572 -2.4.1.99 * allium cepa 70000.0 2 PMID:14658392;PMID:20188876 -2.4.1.99 * asparagus officinalis 65000.0 1 * -2.4.1.99 * aspergillus aculeatus 135000.0 2 PMID:17056145 -2.4.1.99 * aspergillus foetidus 180000.0 2 PMID:9495772 -2.4.1.99 * cenchrus americanus 70500.0 1 * -2.4.1.99 * cichorium intybus 49000.0 1 PMID:19037899 -2.4.1.99 * helianthus tuberosus 90000.0 4 PMID:12226250;PMID:8641462 -2.4.1.99 * hordeum vulgare 61800.0 3 * -2.4.1.99 * lolium perenne 70000.0 1 PMID:14658392;PMID:20188876 -2.4.1.99 * rhodotorula sp. 170000.0 2 PMID:18481059 -2.4.1.99 * taraxacum officinale 61500.0 1 * -2.4.2.1 * acholeplasma laidlawii 108000.0 1 PMID:11337031 -2.4.2.1 * aeropyrum pernix 30000.0 2 PMID:23160980;PMID:23332162 -2.4.2.1 * aneurinibacillus migulanus 87000.0 1 PMID:31888088 -2.4.2.1 * bacillus subtilis 164200.0 5 PMID:21543875;PMID:99174 -2.4.2.1 * bos taurus 100000.0 6 PMID:24686197;PMID:6815176;PMID:7211;PMID:8782414;PMID:9972 -2.4.2.1 * camelus dromedarius 44000.0 1 PMID:2123764 -2.4.2.1 * cellulomonas sp. 114000.0 4 PMID:11337031;PMID:12044910;PMID:9598071 -2.4.2.1 * cricetulus griseus 89000.0 3 PMID:825137;PMID:99640 -2.4.2.1 * enterobacter cloacae 87000.0 1 * -2.4.2.1 * escherichia coli 180000.0 7 PMID:11337031;PMID:11437593;PMID:16751611;PMID:17419725;PMID:235429;PMID:3042752;PMID:3932337 -2.4.2.1 * exiguobacterium acetylicum 31000.0 1 PMID:1368697 -2.4.2.1 * gallus gallus 90000.0 8 PMID:6815176;PMID:7211;PMID:8782414;PMID:99640 -2.4.2.1 * geobacillus stearothermophilus 113000.0 5 PMID:413564;PMID:6815176;PMID:7211;PMID:8782414 -2.4.2.1 * helicobacter pylori 154716.0 2 PMID:28336275 -2.4.2.1 * homo sapiens 94000.0 12 PMID:114517;PMID:24107682;PMID:412851;PMID:413564;PMID:5768862;PMID:6771283;PMID:6783653;PMID:8782414;PMID:99639 -2.4.2.1 * hyalomma dromedarii 58000.0 1 PMID:1905141 -2.4.2.1 * klebsiella sp. 156000.0 1 PMID:11337031 -2.4.2.1 * kluyveromyces lactis 105000.0 1 PMID:27768715 -2.4.2.1 * oryctolagus cuniculus 345000.0 7 PMID:1390;PMID:31138;PMID:414743;PMID:99638 -2.4.2.1 * pectobacterium carotovorum 58000.0 1 PMID:11337031;PMID:1368721 -2.4.2.1 * plasmodium falciparum 170100.0 2 PMID:11337031;PMID:3091593;PMID:33075341 -2.4.2.1 * plasmodium lophurae 128800.0 3 PMID:3920217 -2.4.2.1 * proteus vulgaris 120000.0 1 PMID:11337031;PMID:2111121 -2.4.2.1 * pseudoalteromonas sp. 29000.0 3 PMID:18299797 -2.4.2.1 * pyrococcus furiosus 180000.0 5 PMID:17419725;PMID:3042752 -2.4.2.1 * rattus norvegicus 84000.0 2 PMID:37803 -2.4.2.1 * saccharolobus solfataricus 160000.0 2 PMID:11337031 -2.4.2.1 * salmonella enterica subsp. enterica serovar typhimurium 141000.0 5 PMID:11337031;PMID:235429;PMID:4570469;PMID:99637 -2.4.2.1 * serratia marcescens 170000.0 3 PMID:11337031;PMID:9614697 -2.4.2.1 * streptococcus mutans 33000.0 1 PMID:20054131 -2.4.2.1 * thermus thermophilus 156000.0 2 PMID:22344645 -2.4.2.1 * trypanosoma brucei 68000.0 1 PMID:11337031 -2.4.2.10 * burkholderia cenocepacia 130000.0 1 PMID:39938730 -2.4.2.10 * corynebacterium ammoniagenes 45400.0 2 PMID:17921291 -2.4.2.10 * escherichia coli 47000.0 3 PMID:2419315;PMID:9222315 -2.4.2.10 * homo sapiens 52000.0 3 PMID:17237621;PMID:19020740;PMID:26700594 -2.4.2.10 * mus musculus 51500.0 3 PMID:3839509;PMID:6893554 -2.4.2.10 * mycobacterium tuberculosis 38000.0 3 PMID:22075667 -2.4.2.10 * plasmodium falciparum 158000.0 14 PMID:15003844;PMID:15147974;PMID:15683248;PMID:24507637;PMID:28389349 -2.4.2.10 * rhizobium leguminosarum 24700.0 1 PMID:9305779 -2.4.2.10 * saccharomyces cerevisiae 49000.0 4 PMID:218950;PMID:23315339;PMID:357907 -2.4.2.10 * salmonella enterica subsp. enterica serovar typhimurium 23000.0 1 PMID:2271660 -2.4.2.10 * streptococcus mutans 27000.0 1 PMID:20445243 -2.4.2.12 * [haemophilus] ducreyi 55600.0 1 PMID:11157928 -2.4.2.12 * danio rerio 55000.0 1 PMID:26012732 -2.4.2.12 * homo sapiens 120000.0 6 PMID:19912992;PMID:20506278;PMID:22140607;PMID:25277684;PMID:26040985 -2.4.2.14 * arabidopsis thaliana 54000.0 1 PMID:17616508 -2.4.2.14 * bacillus subtilis 200000.0 4 PMID:6443594;PMID:6794613 -2.4.2.14 * columba livia 181000.0 3 PMID:1262323 -2.4.2.14 * eremothecium gossypii 56700.0 1 PMID:16204483 -2.4.2.14 * escherichia coli 224000.0 4 PMID:372191;PMID:6443594 -2.4.2.14 * gallus gallus 200000.0 3 PMID:228744 -2.4.2.14 * glycine max 8000000.0 1 PMID:6538402 -2.4.2.14 * homo sapiens 270000.0 3 PMID:6175188 -2.4.2.14 * mus musculus 292000.0 2 PMID:6175188 -2.4.2.14 * phaseolus vulgaris 55000.0 1 PMID:27004600 -2.4.2.14 * rattus norvegicus 215000.0 4 PMID:447621;PMID:6175188 -2.4.2.14 * schizosaccharomyces pombe 360000.0 1 PMID:4371850 -2.4.2.17 * arabidopsis thaliana 44800.0 2 PMID:10712555 -2.4.2.17 * campylobacter jejuni 202000.0 4 PMID:27191057;PMID:29208762 -2.4.2.17 * corynebacterium glutamicum 192000.0 4 PMID:22172596 -2.4.2.17 * escherichia coli 186000.0 2 PMID:11185885 -2.4.2.17 * mycobacterium tuberculosis 180000.0 1 PMID:22989207 -2.4.2.17 * salmonella enterica subsp. enterica serovar typhimurium 221000.0 4 PMID:4368347;PMID:5337591 -2.4.2.17 * thermotoga maritima 220000.0 1 PMID:15660995 -2.4.2.18 * aeromonas caviae 67000.0 1 PMID:1116988;PMID:338606 -2.4.2.18 * coprococcus eutactus 75000.0 1 PMID:31134642 -2.4.2.18 * enterobacter liquefaciens 45000.0 1 PMID:1116988;PMID:786623 -2.4.2.18 * hafnia alvei 70000.0 3 PMID:1116988;PMID:28781961;PMID:3199444;PMID:32668;PMID:338606 -2.4.2.18 * klebsiella aerogenes 170000.0 2 PMID:4352716 -2.4.2.18 * methanocella conradii 78200.0 1 PMID:31134642 -2.4.2.18 * methanococcus voltae 83700.0 1 PMID:31134642 -2.4.2.18 * morganella morganii 67000.0 1 PMID:1116988;PMID:338606 -2.4.2.18 * ogataea henricii 70000.0 1 PMID:28781961;PMID:3199444;PMID:32668 -2.4.2.18 * pectobacterium carotovorum 67000.0 2 PMID:1116988;PMID:338606 -2.4.2.18 * petrotoga mobilis 78700.0 1 PMID:31134642 -2.4.2.18 * proteus vulgaris 67000.0 1 PMID:1116988;PMID:338606 -2.4.2.18 * saccharolobus solfataricus 79200.0 5 PMID:11298741;PMID:18164726;PMID:31134642 -2.4.2.18 * saccharomyces cerevisiae 83000.0 2 PMID:2651124 -2.4.2.18 * salmonella enterica subsp. enterica serovar typhimurium 320000.0 5 PMID:4350997 -2.4.2.18 * serratia marcescens 45000.0 2 PMID:1116988;PMID:786623 -2.4.2.18 * serratia rubidaea 45000.0 1 PMID:1116988;PMID:786623 -2.4.2.18 * thermococcus kodakarensis 70000.0 1 PMID:28781961;PMID:3199444;PMID:32668 -2.4.2.19 * cupriavidus necator 210000.0 2 PMID:24123;PMID:7374514 -2.4.2.19 * escherichia coli 70000.0 2 PMID:8561507 -2.4.2.19 * homo sapiens 170000.0 3 PMID:3139649 -2.4.2.19 * lentinula edodes 160000.0 1 PMID:4373551 -2.4.2.19 * mycobacterium tuberculosis 58000.0 1 PMID:24949952 -2.4.2.19 * pseudomonas sp. 178000.0 1 * -2.4.2.19 * rattus norvegicus 160000.0 2 PMID:3926003 -2.4.2.19 * ricinus communis 72000.0 3 PMID:4422841;PMID:8419294 -2.4.2.19 * saccharomyces cerevisiae 191000.0 1 PMID:18321072 -2.4.2.19 * salmonella enterica subsp. enterica serovar typhimurium 72000.0 2 PMID:4422841;PMID:8419294 -2.4.2.19 * streptococcus pyogenes 31700.0 1 PMID:23204464 -2.4.2.19 * streptococcus pyogenes serotype m4 212300.0 2 PMID:28618168 -2.4.2.19 * sus scrofa 210000.0 8 PMID:23626766;PMID:24123;PMID:4826469;PMID:7374514 -2.4.2.19 * thermotoga maritima 30048.0 1 PMID:15103640 -2.4.2.2 * geobacillus stearothermophilus 85000.0 3 PMID:4978445 -2.4.2.2 * haemophilus influenzae 92000.0 2 PMID:8782414 -2.4.2.2 * thermus thermophilus 86300.0 2 PMID:17401202 -2.4.2.21 * propionibacterium freudenreichii 66400.0 1 PMID:26597297 -2.4.2.21 * pseudomonas denitrificans (nom. rej.) 71000.0 2 PMID:1917841 -2.4.2.21 * sporomusa ovata 36650.0 2 PMID:21696461 -2.4.2.22 * enterococcus faecalis 42000.0 1 PMID:4216296 -2.4.2.22 * leishmania donovani 62000.0 3 PMID:19861168;PMID:7356667 -2.4.2.24 * physcomitrium patens 78700.0 1 PMID:25139408 -2.4.2.24 * plantago ovata 76300.0 1 PMID:25139408 -2.4.2.25 * petroselinum crispum 50000.0 1 PMID:4650134 -2.4.2.26 * gallus gallus 120000.0 4 PMID:4214614;PMID:5030630 -2.4.2.26 * homo sapiens 120000.0 8 PMID:11087729;PMID:11099377;PMID:15461586;PMID:17437056;PMID:18023272;PMID:19100717 -2.4.2.26 * rattus norvegicus 78000.0 2 PMID:10929006 -2.4.2.27 * streptomyces griseus 63000.0 2 PMID:6768553 -2.4.2.28 * arabidopsis thaliana 28450.0 3 PMID:18342331;PMID:18945934 -2.4.2.28 * bos taurus 98000.0 3 PMID:2108157;PMID:3091600 -2.4.2.28 * homo sapiens 98000.0 8 PMID:1903946;PMID:2108157;PMID:26910893;PMID:3091600;PMID:7732755;PMID:8687427 -2.4.2.28 * leishmania donovani 89000.0 1 * -2.4.2.28 * mycobacterium tuberculosis 60000.0 2 PMID:22225784 -2.4.2.28 * pyrococcus furiosus 180000.0 2 PMID:12664268;PMID:15819883 -2.4.2.28 * rattus norvegicus 90000.0 2 PMID:114225 -2.4.2.28 * saccharolobus solfataricus 180000.0 12 PMID:10336870;PMID:11699643;PMID:12664268;PMID:15819883;PMID:7929153;PMID:8774706 -2.4.2.28 * trypanosoma brucei 34000.0 1 PMID:27036940 -2.4.2.28 * uncultured bacterium 97000.0 3 PMID:23383268 -2.4.2.29 * methanosarcina acetivorans 150000.0 3 PMID:23201278 -2.4.2.29 * zymomonas mobilis 113100.0 3 PMID:19627989 -2.4.2.3 * acholeplasma laidlawii 65000.0 1 PMID:6619095 -2.4.2.3 * aeropyrum pernix 185300.0 2 PMID:23160980 -2.4.2.3 * escherichia coli 160000.0 6 PMID:16751;PMID:24910260;PMID:3546298;PMID:6356978;PMID:9526114 -2.4.2.3 * giardia duodenalis 43000.0 2 PMID:3185613 -2.4.2.3 * homo sapiens 33000.0 1 PMID:12084455 -2.4.2.3 * lacticaseibacillus casei 80000.0 2 PMID:2119230 -2.4.2.3 * mus musculus 35000.0 1 PMID:9850074 -2.4.2.3 * rattus norvegicus 110000.0 5 PMID:2981897;PMID:4826883;PMID:692394 -2.4.2.3 * salmonella enterica subsp. enterica serovar typhimurium 165000.0 2 PMID:3546298;PMID:9526114 -2.4.2.3 * schistosoma mansoni 56000.0 1 PMID:3360774 -2.4.2.3 * shewanella oneidensis 27000.0 1 PMID:23975397;PMID:25478848 -2.4.2.3 * vibrio cholerae 28000.0 3 PMID:23143257;PMID:24419619 -2.4.2.3 * yersinia pseudotuberculosis 27500.0 1 * -2.4.2.30 * bacillus cereus 120000.0 3 PMID:22934824 -2.4.2.30 * cistus incanus 80000.0 1 PMID:21356593 -2.4.2.30 * clostridium botulinum 25000.0 1 PMID:23485441;PMID:3127209 -2.4.2.30 * dictyostelium discoideum 116000.0 2 * -2.4.2.30 * homo sapiens 116000.0 3 PMID:23485441;PMID:2434482;PMID:3127209 -2.4.2.30 * mus musculus 30000.0 1 PMID:26209623 -2.4.2.30 * neisseria meningitidis 17000.0 2 PMID:21367854;PMID:25996923 -2.4.2.30 * paenibacillus larvae subsp. larvae 22000.0 1 PMID:25477523 -2.4.2.30 * pseudomonas aeruginosa 300000.0 1 PMID:8418052 -2.4.2.30 * saccharolobus solfataricus 50000.0 3 PMID:11040421 -2.4.2.30 * streptomyces scabiei 22000.0 2 PMID:27002155 -2.4.2.31 * clostridioides difficile 43000.0 1 PMID:3137166 -2.4.2.31 * clostridium botulinum 49000.0 1 PMID:25058685 -2.4.2.31 * clostridium perfringens 47000.0 1 PMID:25058685 -2.4.2.31 * cricetulus griseus 31000.0 1 PMID:21616557 -2.4.2.31 * gallus gallus 45000.0 9 PMID:15842200;PMID:9193646;PMID:9193647;PMID:9193660 -2.4.2.31 * homo sapiens 50000.0 2 PMID:22701565;PMID:24676941;PMID:26847718 -2.4.2.31 * meleagris gallopavo 32000.0 7 PMID:3099839;PMID:6247348;PMID:6403540;PMID:6436644 -2.4.2.31 * mus musculus 37000.0 1 PMID:24676941;PMID:26847718 -2.4.2.31 * neisseria meningitidis 18000.0 2 PMID:21367854;PMID:23964075 -2.4.2.31 * oryctolagus cuniculus 40000.0 5 PMID:1454819;PMID:2120212;PMID:8431475 -2.4.2.31 * tequatrovirus t4 26000.0 1 PMID:199442 -2.4.2.35 * tulipa hybrid cultivar 30000.0 1 * -2.4.2.36 * pseudomonas aeruginosa 72000.0 1 PMID:6254804 -2.4.2.36 * vibrio cholerae serotype o1 21000.0 1 PMID:19364533 -2.4.2.37 * azospirillum brasilense 37000.0 1 PMID:19131333 -2.4.2.37 * rhodospirillum rubrum 30900.0 3 PMID:23574616;PMID:3141411 -2.4.2.38 * arabidopsis thaliana 62000.0 2 PMID:10781814;PMID:12770780 -2.4.2.38 * cryptococcus neoformans 90000.0 2 PMID:17430900 -2.4.2.38 * glycine max 59000.0 1 PMID:9395463 -2.4.2.38 * zea mays 56000.0 1 PMID:16920165 -2.4.2.39 * arabidopsis thaliana 51000.0 1 PMID:18557833 -2.4.2.4 * escherichia coli 98000.0 5 PMID:19434693;PMID:24910260;PMID:3546318;PMID:357904 -2.4.2.4 * homo sapiens 121000.0 15 PMID:1094953;PMID:12174926;PMID:12188887;PMID:18765464;PMID:19434693;PMID:24407036;PMID:30138393;PMID:718961;PMID:7284378;PMID:7536129;PMID:8407883 -2.4.2.4 * lacticaseibacillus casei 80000.0 2 PMID:2119230 -2.4.2.4 * mus musculus 110000.0 2 PMID:19434693;PMID:25287063 -2.4.2.4 * rattus norvegicus 110000.0 1 PMID:19434693 -2.4.2.4 * salmonella enterica subsp. enterica serovar typhimurium 100000.0 5 PMID:1094953;PMID:26919527;PMID:30138393;PMID:357903 -2.4.2.40 * phaseolus vulgaris 51000.0 2 PMID:10364407;PMID:16593839 -2.4.2.41 * arabidopsis thaliana 56600.0 1 PMID:18460606 -2.4.2.43 * burkholderia cenocepacia 66300.0 1 PMID:26030265;PMID:26515403 -2.4.2.43 * salmonella enterica 66300.0 2 PMID:26030265;PMID:26515403 -2.4.2.43 * salmonella enterica subsp. enterica serovar typhimurium 59000.0 1 PMID:16226890 -2.4.2.45 * mycobacterium tuberculosis 33000.0 2 PMID:15878857 -2.4.2.47 * mycobacterium tuberculosis 38000.0 1 PMID:21595486 -2.4.2.48 * haloferax volcanii 78000.0 1 PMID:9242689 -2.4.2.48 * methanosarcina acetivorans 150000.0 3 PMID:23201278 -2.4.2.48 * pyrococcus horikoshii 66000.0 1 PMID:12054814 -2.4.2.52 * escherichia coli 32600.0 1 PMID:10924139 -2.4.2.54 * archaeoglobus fulgidus 57000.0 2 PMID:12142414 -2.4.2.54 * methanocaldococcus jannaschii 70000.0 2 PMID:15262968 -2.4.2.54 * methanosarcina thermophila 65000.0 4 PMID:12142414;PMID:9698382 -2.4.2.54 * methanothermobacter thermautotrophicus 69000.0 1 PMID:31663056 -2.4.2.55 * sporomusa ovata 361800.0 3 PMID:21696461 -2.4.2.56 * euonymus alatus 48000.0 1 * -2.4.2.6 * crithidia luciliae 17000.0 1 PMID:2026165 -2.4.2.6 * lactobacillus helveticus 86000.0 3 PMID:11836245;PMID:5156378;PMID:692395 -2.4.2.6 * lactobacillus leichmannii 120000.0 7 PMID:18487606;PMID:2406239;PMID:8839981 -2.4.2.6 * lactococcus lactis 69000.0 4 PMID:17881307 -2.4.2.6 * lentilactobacillus hilgardii 22000.0 1 PMID:28837850 -2.4.2.6 * limosilactobacillus fermentum 18900.0 3 PMID:18487606;PMID:22092712 -2.4.2.6 * limosilactobacillus reuteri 112700.0 2 PMID:20048065 -2.4.2.6 * peribacillus psychrosaccharolyticus 91400.0 2 PMID:25090115 -2.4.2.6 * rattus norvegicus 40520.0 5 PMID:17234634 -2.4.2.6 * trypanosoma brucei brucei 39070.0 1 * -2.4.2.60 * arabidopsis thaliana 241940.0 3 PMID:24637331 -2.4.2.62 * homo sapiens 230000.0 1 PMID:8982869 -2.4.2.64 * rattus norvegicus 80000.0 1 PMID:6986171 -2.4.2.64 * triticum aestivum 140000.0 1 PMID:7142141 -2.4.2.7 * arabidopsis thaliana 54000.0 4 PMID:12010467;PMID:2275559 -2.4.2.7 * artemia sp. 28000.0 2 PMID:1850982 -2.4.2.7 * brassica juncea 54000.0 2 PMID:2275559 -2.4.2.7 * escherichia coli 40000.0 1 PMID:357906 -2.4.2.7 * hevea brasiliensis 54000.0 2 * -2.4.2.7 * homo sapiens 46000.0 6 PMID:15196008;PMID:3531209;PMID:4349039;PMID:457664;PMID:692402 -2.4.2.7 * leishmania donovani 29000.0 2 PMID:2704389;PMID:7356667 -2.4.2.7 * mus musculus 44000.0 2 PMID:3768421 -2.4.2.7 * plasmodium chabaudi 34000.0 1 PMID:4471692 -2.4.2.7 * plasmodium falciparum 18000.0 1 PMID:2665821 -2.4.2.7 * rattus norvegicus 22000.0 2 PMID:236779;PMID:692403 -2.4.2.7 * saccharolobus solfataricus 45000.0 2 PMID:24158498 -2.4.2.7 * saccharomyces cerevisiae 50000.0 3 PMID:7660983 -2.4.2.7 * schizosaccharomyces pombe 50000.0 2 PMID:20306 -2.4.2.7 * triticum aestivum 23000.0 1 PMID:7092211 -2.4.2.7 * zea mays 22760.0 1 PMID:18464041 -2.4.2.8 * artemia sp. 66000.0 2 PMID:1850982 -2.4.2.8 * caldanaerobacter subterraneus subsp. tengcongensis 87400.0 2 PMID:14965769 -2.4.2.8 * cricetulus griseus 85000.0 3 PMID:4368495;PMID:692400 -2.4.2.8 * gallus gallus 85000.0 2 PMID:3996588 -2.4.2.8 * giardia duodenalis 63000.0 2 PMID:3087975 -2.4.2.8 * helicobacter pylori 38600.0 1 PMID:33891818 -2.4.2.8 * homo sapiens 100000.0 8 PMID:2199439;PMID:23907213;PMID:5129729;PMID:6093778;PMID:692400;PMID:861217;PMID:880943 -2.4.2.8 * leishmania donovani 24000.0 1 PMID:2704389 -2.4.2.8 * leishmania tarentolae 50000.0 2 PMID:12147338 -2.4.2.8 * mus musculus 80000.0 2 PMID:237883 -2.4.2.8 * mycobacterium tuberculosis 96000.0 4 PMID:28082125 -2.4.2.8 * plasmodium chabaudi 71000.0 1 PMID:4471692 -2.4.2.8 * plasmodium falciparum 26000.0 1 PMID:25824378 -2.4.2.8 * plasmodium lophurae 79000.0 1 PMID:3574349 -2.4.2.8 * pyrococcus horikoshii 103100.0 2 PMID:18405676 -2.4.2.8 * rattus norvegicus 72000.0 1 PMID:992564 -2.4.2.8 * saccharolobus solfataricus 45000.0 2 PMID:24158498 -2.4.2.8 * saccharomyces cerevisiae 54800.0 3 PMID:371963;PMID:6170313 -2.4.2.8 * schistosoma mansoni 105000.0 3 PMID:2199439;PMID:3941107;PMID:880943 -2.4.2.8 * schizosaccharomyces pombe 48000.0 2 PMID:20306 -2.4.2.8 * streptomyces cyanogenus 150000.0 2 * -2.4.2.8 * trypanosoma brucei brucei 106000.0 3 PMID:27786284 -2.4.2.9 * [bacillus] caldolyticus 46000.0 1 PMID:9268683 -2.4.2.9 * acholeplasma laidlawii 80000.0 1 PMID:216696;PMID:6619094 -2.4.2.9 * arabidopsis thaliana 53000.0 1 PMID:17143579 -2.4.2.9 * candida albicans 47000.0 2 PMID:8047103 -2.4.2.9 * crithidia luciliae 80000.0 1 * -2.4.2.9 * escherichia coli 111000.0 7 PMID:1371255;PMID:3513846;PMID:8856065 -2.4.2.9 * giardia duodenalis 76000.0 2 PMID:7622327 -2.4.2.9 * homo sapiens 38500.0 2 PMID:17384901 -2.4.2.9 * leishmania donovani 100000.0 2 PMID:23986453 -2.4.2.9 * mycobacterium tuberculosis 120000.0 5 PMID:23424660;PMID:26456658 -2.4.2.9 * saccharolobus shibatae 250000.0 1 PMID:8765224 -2.4.2.9 * saccharolobus solfataricus 98000.0 1 PMID:15752360 -2.4.2.9 * saccharomyces cerevisiae 80000.0 1 PMID:216696;PMID:6619094 -2.4.2.9 * syrian hamster adenovirus 20000.0 1 PMID:23444104 -2.4.2.9 * tetrahymena pyriformis 36000.0 1 PMID:26316 -2.4.2.9 * toxoplasma gondii 28000.0 3 PMID:9247925 -2.4.3.1 * bombyx mori 53100.0 2 PMID:26306633 -2.4.3.1 * bos taurus 80000.0 8 PMID:849932 -2.4.3.1 * cricetulus griseus 45000.0 1 PMID:22205442 -2.4.3.1 * helicobacter cetorum 78800.0 1 PMID:31281932 -2.4.3.1 * homo sapiens 57000.0 5 PMID:20656882;PMID:21930713;PMID:23999306;PMID:25365915 -2.4.3.1 * mus musculus 70000.0 3 PMID:12966079;PMID:21930713;PMID:22039275 -2.4.3.1 * photobacterium damselae 64000.0 2 PMID:8864851 -2.4.3.1 * photobacterium sp. 59000.0 3 PMID:17671362;PMID:17984122 -2.4.3.1 * rattus norvegicus 40500.0 2 PMID:19500344;PMID:7142179 -2.4.3.2 * rattus norvegicus 44000.0 1 PMID:2262006 -2.4.3.2 * vibrio sp. 43921.0 1 PMID:17673486 -2.4.3.3 * bos taurus 120000.0 1 PMID:4019457 -2.4.3.3 * homo sapiens 104000.0 6 PMID:11984005;PMID:15466199;PMID:19788761;PMID:25281698 -2.4.3.3 * sus scrofa 172000.0 2 PMID:447688 -2.4.3.4 * sus scrofa 50000.0 4 PMID:4055734;PMID:438196;PMID:438198 -2.4.3.6 * helicobacter bizzozeronii 80000.0 1 PMID:22408169 -2.4.3.6 * photobacterium phosphoreum 45026.0 2 PMID:17702755 -2.4.3.6 * photobacterium sp. jt-ish-224 56732.0 1 PMID:17984122 -2.4.3.6 * vibrio sp. jt-faj-16 43921.0 1 PMID:17673486 -2.4.3.7 * homo sapiens 34900.0 1 PMID:11062056 -2.4.3.8 * gallus gallus 95000.0 2 PMID:10737630 -2.4.3.8 * homo sapiens 50000.0 1 PMID:22184126 -2.4.3.8 * neisseria meningitidis 100000.0 1 PMID:17662040 -2.4.3.8 * rattus norvegicus 55000.0 1 PMID:2302211 -2.4.3.8 * xenopus laevis 47200.0 1 PMID:17333390 -2.4.3.9 * homo sapiens 60000.0 1 PMID:15061693;PMID:1999428;PMID:2222467 -2.4.3.9 * rattus norvegicus 76000.0 2 PMID:15061693;PMID:1999428;PMID:2222467;PMID:8253749 -2.4.99.12 * aquifex aeolicus 42000.0 1 PMID:19546212 -2.4.99.12 * chlamydia psittaci 46615.0 1 PMID:7523826 -2.4.99.12 * chlamydia trachomatis 45851.0 1 PMID:1382060 -2.4.99.12 * escherichia coli 43000.0 1 PMID:1577828 -2.4.99.13 * chlamydia psittaci 46615.0 1 PMID:7523826 -2.4.99.13 * chlamydia trachomatis 45851.0 1 PMID:1382060 -2.4.99.13 * escherichia coli 43000.0 1 PMID:1577828 -2.4.99.14 * chlamydia psittaci 46615.0 1 PMID:7523826 -2.4.99.14 * chlamydia trachomatis 45851.0 1 PMID:1382060 -2.4.99.17 * escherichia coli 65000.0 3 PMID:8347586 -2.4.99.17 * thermotoga maritima 38529.0 1 PMID:15822125 -2.4.99.18 * canis lupus familiaris 700000.0 6 PMID:1555242;PMID:15835887 -2.4.99.18 * gallus gallus 60000.0 1 PMID:3297152;PMID:4039727 -2.4.99.18 * leishmania major 480000.0 5 PMID:18596231;PMID:18955371 -2.4.99.18 * oryza sativa 48000.0 1 * -2.4.99.18 * pyrococcus furiosus 230000.0 2 PMID:18046457 -2.4.99.18 * saccharomyces cerevisiae 550000.0 19 PMID:16096346;PMID:18596231;PMID:18955371;PMID:20047336;PMID:3297152;PMID:9405463;PMID:9878773 -2.4.99.18 * sus scrofa 69300.0 3 PMID:11443278 -2.4.99.19 * campylobacter jejuni 82000.0 1 PMID:20331969 -2.4.99.23 * campylobacter coli 39317.0 1 PMID:9831648 -2.4.99.23 * campylobacter jejuni 39381.0 1 PMID:9831648 -2.4.99.23 * escherichia coli 37000.0 2 PMID:35508636;PMID:9446588 -2.4.99.24 * haemophilus influenzae 38903.0 1 PMID:9119477 -2.4.99.26 * escherichia coli 64000.0 1 PMID:22158874 -2.4.99.26 * pseudomonas aeruginosa 70000.0 1 PMID:17697256 -2.4.99.28 * escherichia coli 90000.0 2 PMID:6389538;PMID:7030331 -2.4.99.28 * priestia megaterium 61000.0 1 PMID:6802846 -2.4.99.28 * pseudomonas aeruginosa 62856.0 2 PMID:20580675 -2.5.1.1 * catharanthus roseus 38000.0 1 PMID:23543438 -2.5.1.1 * corynebacterium glutamicum 158000.0 2 PMID:25181035 -2.5.1.1 * dendroctonus ponderosae 49400.0 1 PMID:24167290 -2.5.1.1 * phaedon cochleariae 93800.0 3 PMID:23440195 -2.5.1.1 * picea abies 40000.0 1 PMID:19939949 -2.5.1.10 * abies grandis 110000.0 1 PMID:11368347 -2.5.1.10 * anthonomus grandis 103000.0 3 PMID:19309001 -2.5.1.10 * bacillus subtilis 67000.0 1 PMID:6792191 -2.5.1.10 * catharanthus roseus 39900.0 1 PMID:21872968 -2.5.1.10 * chimonanthus praecox 100000.0 1 PMID:20855217 -2.5.1.10 * dendrobium nobile 40000.0 1 PMID:36202944 -2.5.1.10 * homo sapiens 74000.0 2 PMID:24369118;PMID:4021811 -2.5.1.10 * matricaria chamomilla var. recutita 43000.0 2 PMID:25729967 -2.5.1.10 * megoura viciae 45300.0 1 PMID:36533988 -2.5.1.10 * panax ginseng 56000.0 1 * -2.5.1.10 * penicillium brevicompactum 39700.0 1 PMID:26334936 -2.5.1.10 * phaedon cochleariae 93800.0 3 PMID:23440195 -2.5.1.10 * phaffia rhodozyma 40240.0 1 PMID:24796858 -2.5.1.10 * pinus massoniana 39800.0 1 * -2.5.1.10 * platycodon grandiflorus 46201.0 1 PMID:38738769 -2.5.1.10 * pseudomonas aeruginosa 34018.0 1 PMID:25760619 -2.5.1.10 * rhopalosiphum padi 45900.0 2 PMID:22588726 -2.5.1.10 * ricinus communis 72500.0 3 PMID:4371817 -2.5.1.10 * rosa rugosa 39570.0 2 PMID:38435988 -2.5.1.10 * sanghuangporus baumii 40730.0 1 PMID:31897972 -2.5.1.10 * sporobolomyces pararoseus 60000.0 5 PMID:38666925 -2.5.1.10 * sundstroemia setigera 53000.0 1 PMID:25996801 -2.5.1.10 * toxoplasma gondii 75000.0 3 PMID:22931372 -2.5.1.10 * tripterygium wilfordii 58000.0 2 PMID:25938487 -2.5.1.10 * zea mays 40800.0 2 PMID:25680349 -2.5.1.100 * aspergillus fumigatus 110000.0 1 PMID:16397874 -2.5.1.104 * pyrococcus furiosus 65000.0 3 PMID:17545282 -2.5.1.104 * thermus thermophilus 130000.0 3 PMID:15983049;PMID:21458463 -2.5.1.105 * methanocaldococcus jannaschii 33076.0 1 PMID:10426953 -2.5.1.106 * aspergillus fumigatus 66000.0 3 PMID:16000710 -2.5.1.107 * aspergillus fischeri 268000.0 3 PMID:23109474 -2.5.1.108 * pyrococcus horikoshii 34000.0 1 PMID:20931132 -2.5.1.108 * saccharomyces cerevisiae 60000.0 2 PMID:8406038 -2.5.1.109 * aspergillus sp. 292000.0 2 PMID:20722388 -2.5.1.109 * aspergillus terreus 62000.0 1 PMID:25125042 -2.5.1.109 * aspergillus versicolor 45000.0 1 PMID:22660767 -2.5.1.110 * aspergillus fumigatus 50100.0 1 PMID:18683158 -2.5.1.111 * streptomyces niveus 40000.0 1 PMID:19557032 -2.5.1.111 * streptomyces roseochromogenus subsp. oscitans 39900.0 2 PMID:12618544;PMID:17077503 -2.5.1.112 * humulus lupulus 37000.0 2 PMID:15381407 -2.5.1.112 * morus alba 35810.0 1 PMID:17320045 -2.5.1.115 * chlamydomonas reinhardtii 30974.0 1 PMID:26454640 -2.5.1.115 * elaeis guineensis 44400.0 1 * -2.5.1.115 * elaeis oleifera 44400.0 1 * -2.5.1.116 * elaeis guineensis 51600.0 1 * -2.5.1.116 * elaeis oleifera 51600.0 1 * -2.5.1.121 * streptomyces anulatus 37138.0 2 PMID:19339241 -2.5.1.122 * aspergillus niger 228000.0 4 PMID:24970457 -2.5.1.122 * plenodomus lingam 100000.0 2 PMID:19762440 -2.5.1.123 * streptomyces virginiae 39100.0 3 PMID:17543953 -2.5.1.126 * pyrobaculum aerophilum 37000.0 2 PMID:19822146 -2.5.1.127 * hyperthermus butylicus 35000.0 2 PMID:19822146 -2.5.1.131 * methanocaldococcus jannaschii 37000.0 1 PMID:26100040 -2.5.1.132 * homo sapiens 40000.0 1 PMID:10749855 -2.5.1.132 * oncorhynchus mykiss 80000.0 1 PMID:10438460 -2.5.1.141 * bacillus subtilis 33800.0 1 PMID:19204012 -2.5.1.141 * escherichia coli 28000.0 2 PMID:8253713 -2.5.1.147 * methanocaldococcus jannaschii 40000.0 1 PMID:14593448 -2.5.1.147 * mycolicibacterium smegmatis 88000.0 1 PMID:14593448 -2.5.1.15 * burkholderia cenocepacia 68000.0 1 PMID:21554707 -2.5.1.15 * escherichia coli 52000.0 2 PMID:4304228 -2.5.1.15 * escherichia coli mc4100 54000.0 2 PMID:1657875 -2.5.1.15 * francisella tularensis 53000.0 2 PMID:21152407 -2.5.1.15 * lathyrus oleraceus 300000.0 2 PMID:11931659;PMID:9118956 -2.5.1.15 * mycobacterium leprae 60000.0 1 PMID:10542185 -2.5.1.15 * mycobacterium tuberculosis 75000.0 5 PMID:10542185;PMID:18680522 -2.5.1.15 * plasmodium chabaudi 190000.0 1 PMID:4435732;PMID:7374502 -2.5.1.15 * plasmodium falciparum 222000.0 3 PMID:15279950;PMID:31883412;PMID:9391132 -2.5.1.15 * plasmodium vivax 174000.0 1 PMID:27161627 -2.5.1.15 * pneumocystis carinii 71500.0 1 PMID:8397083 -2.5.1.15 * saccharomyces cerevisiae 110000.0 1 PMID:15866722 -2.5.1.15 * staphylococcus aureus 61300.0 1 PMID:9149138 -2.5.1.151 * homo sapiens 28900.0 1 PMID:21697092 -2.5.1.153 * mycobacterium tuberculosis 60000.0 2 PMID:21228491 -2.5.1.158 * micrococcus luteus 55000.0 1 PMID:21068379 -2.5.1.16 * arabidopsis thaliana 750000.0 1 PMID:12368503 -2.5.1.16 * bos taurus 73000.0 4 PMID:2730590;PMID:6312269;PMID:6743257;PMID:7103507 -2.5.1.16 * brassica rapa subsp. pekinensis 81000.0 1 PMID:16663475;PMID:16664325 -2.5.1.16 * caenorhabditis elegans 38000.0 2 PMID:16226262 -2.5.1.16 * escherichia coli 73000.0 7 PMID:23001854;PMID:4572733;PMID:4628436;PMID:6312268 -2.5.1.16 * gentiana triflora 35000.0 1 PMID:26056006 -2.5.1.16 * glycine max 74000.0 1 PMID:10806333 -2.5.1.16 * helicobacter pylori 158000.0 6 PMID:15502329;PMID:16009566;PMID:17357156 -2.5.1.16 * homo sapiens 62000.0 2 PMID:2730590 -2.5.1.16 * hyoscyamus niger 35000.0 1 PMID:9517003 -2.5.1.16 * leishmania donovani 33000.0 1 PMID:25511700 -2.5.1.16 * mus musculus 60000.0 2 PMID:16515550 -2.5.1.16 * nicotiana sylvestris 35000.0 1 PMID:9517003 -2.5.1.16 * olea europaea 36932.0 1 PMID:20532909 -2.5.1.16 * panax ginseng 36390.0 2 PMID:19685160 -2.5.1.16 * plasmodium falciparum 70000.0 2 PMID:15913804;PMID:6312269;PMID:7103507 -2.5.1.16 * rattus norvegicus 73000.0 2 PMID:15913804;PMID:6312269;PMID:7103507 -2.5.1.16 * senecio vulgaris 37000.0 1 PMID:10945218 -2.5.1.16 * synechococcus elongatus 67000.0 3 PMID:28299555;PMID:30877192 -2.5.1.16 * thermotoga maritima 131000.0 1 PMID:11731804 -2.5.1.16 * trypanosoma brucei 37000.0 2 PMID:17916066 -2.5.1.16 * trypanosoma brucei brucei 74000.0 1 PMID:6513985 -2.5.1.160 * spinacia oleracea 215000.0 1 PMID:7840669 -2.5.1.17 * bos taurus 58000.0 2 PMID:12514191 -2.5.1.17 * homo sapiens 58000.0 4 PMID:12514191 -2.5.1.17 * pseudomonas denitrificans (nom. rej.) 70000.0 3 PMID:1917862 -2.5.1.17 * salmonella enterica 36812.0 2 PMID:15547259;PMID:24336938 -2.5.1.17 * salmonella enterica subsp. enterica serovar typhimurium 42000.0 4 PMID:11160088;PMID:7860601 -2.5.1.17 * serratia plymuthica 44000.0 1 PMID:6441836 -2.5.1.17 * sulfurisphaera tokodaii 60000.0 7 PMID:17492665 -2.5.1.18 * acipenser transmontanus 26027.0 2 PMID:15670627 -2.5.1.18 * alitta succinea 30000.0 2 PMID:17459495 -2.5.1.18 * ancylostoma caninum 30000.0 2 PMID:16177370;PMID:17897613 -2.5.1.18 * anopheles dirus 25000.0 1 PMID:16153184;PMID:26443689 -2.5.1.18 * anopheles gambiae 24000.0 1 PMID:18569345 -2.5.1.18 * apis mellifera macedonica 29000.0 2 PMID:15556070 -2.5.1.18 * arabidopsis thaliana 28000.0 2 PMID:16538523 -2.5.1.18 * aspergillus nidulans 51000.0 2 PMID:17459379;PMID:19171936 -2.5.1.18 * atactodea striata 48000.0 2 PMID:12893269;PMID:15826502;PMID:412843 -2.5.1.18 * bemisia tabaci 23500.0 1 PMID:15041016 -2.5.1.18 * bombyx mori 29806.0 6 PMID:15950511;PMID:19022397;PMID:23916611;PMID:24786099;PMID:25758588 -2.5.1.18 * bos taurus 53000.0 3 PMID:18221006;PMID:6725231;PMID:7126177 -2.5.1.18 * cavia porcellus 47000.0 2 PMID:17427177;PMID:914790 -2.5.1.18 * chlamys islandica 44000.0 2 PMID:6654851;PMID:7327268 -2.5.1.18 * clonorchis sinensis 26000.0 2 PMID:17897613;PMID:23916611;PMID:24786099 -2.5.1.18 * cydia pomonella 24190.0 1 PMID:25640718 -2.5.1.18 * dermatophagoides pteronyssinus 25705.0 1 PMID:16499649 -2.5.1.18 * drosophila melanogaster 60000.0 7 PMID:15820751;PMID:24533905;PMID:29578047 -2.5.1.18 * echinococcus granulosus 50000.0 3 PMID:16153184;PMID:20034460;PMID:26443689 -2.5.1.18 * enterobacter cloacae 22500.0 1 PMID:2614380 -2.5.1.18 * escherichia coli 22500.0 1 PMID:2614380 -2.5.1.18 * fasciola gigantica 50000.0 3 PMID:11485575;PMID:19467220;PMID:19619366;PMID:29235505;PMID:32663558;PMID:6838840 -2.5.1.18 * gallus gallus 58000.0 5 PMID:15826502;PMID:19247857;PMID:3091071;PMID:6661188;PMID:7358335;PMID:7469418 -2.5.1.18 * glycine max 49000.0 2 PMID:3987901;PMID:4088072;PMID:6725231;PMID:6838589;PMID:7126177 -2.5.1.18 * haliotis discus 65000.0 4 PMID:18703158 -2.5.1.18 * haliotis discus discus 27400.0 2 PMID:19689930 -2.5.1.18 * hevea brasiliensis 50000.0 1 PMID:11485575;PMID:29235505;PMID:32663558;PMID:6838840 -2.5.1.18 * homo sapiens 49000.0 13 PMID:17587159;PMID:18796433;PMID:23280616;PMID:3003505;PMID:3092805;PMID:4044571;PMID:6173570;PMID:6517933;PMID:6654851;PMID:7327268 -2.5.1.18 * hordeum vulgare 49000.0 2 PMID:16020429 -2.5.1.18 * hyphantria cunea 23204.0 1 PMID:17284839 -2.5.1.18 * klebsiella oxytoca 22500.0 1 PMID:2614380 -2.5.1.18 * lactuca sativa 48000.0 2 PMID:12893269;PMID:15826502;PMID:7469418 -2.5.1.18 * lathyrus oleraceus 54000.0 6 * -2.5.1.18 * liposcelis paeta 53140.0 6 PMID:19140127 -2.5.1.18 * lolium arundinaceum 30000.0 8 PMID:17640691 -2.5.1.18 * macaca mulatta 48000.0 2 PMID:12893269;PMID:412843 -2.5.1.18 * macrobrachium vollenhovenii 46000.0 2 PMID:15674845 -2.5.1.18 * monopterus albus 52000.0 3 PMID:3987901;PMID:4088072;PMID:6838589 -2.5.1.18 * mucor mucedo 53000.0 2 PMID:16209109 -2.5.1.18 * mus musculus 45000.0 4 PMID:3091071;PMID:6661188;PMID:7358335;PMID:7469418 -2.5.1.18 * myathropa florea 26000.0 1 PMID:23916611;PMID:24786099 -2.5.1.18 * novosphingobium aromaticivorans 59000.0 1 PMID:30541921 -2.5.1.18 * onchocerca volvulus 36000.0 1 PMID:17897613 -2.5.1.18 * oryza sativa 60000.0 5 PMID:19640724 -2.5.1.18 * ovis aries 26000.0 2 PMID:6870266 -2.5.1.18 * pagrus major 47900.0 2 PMID:15610066 -2.5.1.18 * paragonimus westermani 30000.0 2 PMID:17641916 -2.5.1.18 * penaeus vannamei 50000.0 2 PMID:17427177;PMID:914790 -2.5.1.18 * phanerodontia chrysosporium 30019.0 2 PMID:23063695 -2.5.1.18 * phytophthora infestans 46000.0 2 PMID:16797619 -2.5.1.18 * pinus tabuliformis 60000.0 2 PMID:15820751;PMID:24533905 -2.5.1.18 * plasmodium falciparum 104000.0 3 PMID:17897613;PMID:17941979 -2.5.1.18 * plasmodium vivax 100000.0 5 PMID:17459379;PMID:19171936;PMID:19467220;PMID:19619366 -2.5.1.18 * plasmodium yoelii 22000.0 1 PMID:17897613 -2.5.1.18 * populus trichocarpa 25521.0 2 PMID:26026470 -2.5.1.18 * proteus mirabilis 22500.0 1 PMID:2614380 -2.5.1.18 * proteus vulgaris 22500.0 1 PMID:2614380 -2.5.1.18 * pseudomonas aeruginosa 22500.0 1 PMID:2614380 -2.5.1.18 * rattus norvegicus 88000.0 10 PMID:16681369;PMID:3091071;PMID:3987901;PMID:4088072;PMID:6173570;PMID:6661188;PMID:6743313;PMID:6838589;PMID:7173206;PMID:7358335;PMID:7469418 -2.5.1.18 * schistosoma japonicum 58500.0 3 PMID:11488926;PMID:17897613 -2.5.1.18 * schistosoma mansoni 26000.0 1 PMID:17897613 -2.5.1.18 * serratia marcescens 22500.0 1 PMID:2614380 -2.5.1.18 * setaria cervi 49200.0 4 PMID:17367761;PMID:18752976 -2.5.1.18 * sinohyriopsis cumingii 23300.0 1 PMID:25689106 -2.5.1.18 * solenopsis invicta 25500.0 1 PMID:14505691 -2.5.1.18 * sus scrofa 50000.0 13 PMID:11485575;PMID:25640718;PMID:29235505;PMID:32663558;PMID:6654851;PMID:6838840;PMID:7327268 -2.5.1.18 * synechocystis sp. 30000.0 1 PMID:25685659 -2.5.1.18 * syrphus ribesii 26000.0 1 PMID:23916611;PMID:24786099 -2.5.1.18 * taenia crassiceps 54000.0 1 PMID:29032785 -2.5.1.18 * taenia solium 60000.0 6 PMID:15127293;PMID:17897613;PMID:18662665 -2.5.1.18 * trachemys scripta elegans 36800.0 3 PMID:16008560 -2.5.1.18 * trichinella spiralis 24000.0 1 PMID:15950511;PMID:25758588 -2.5.1.18 * triticum aestivum 49500.0 3 PMID:25640718 -2.5.1.18 * wiseana cervinata 50000.0 3 PMID:6696729 -2.5.1.18 * xylella fastidiosa 56000.0 3 PMID:18259055;PMID:18331799 -2.5.1.18 * zea mays 50000.0 3 PMID:11485575;PMID:29235505;PMID:32663558;PMID:6838840 -2.5.1.19 * alcanivorax sp. 45000.0 1 PMID:25039062 -2.5.1.19 * arthrospira sp. 105500.0 6 PMID:25229999 -2.5.1.19 * bacillus cereus 43350.0 1 PMID:23161452 -2.5.1.19 * bacillus subtilis 48000.0 1 PMID:7744055 -2.5.1.19 * calothrix sp. 87400.0 3 PMID:25229999 -2.5.1.19 * camptotheca acuminata 55600.0 1 * -2.5.1.19 * chroococcidiopsis thermalis 93800.0 2 PMID:25229999 -2.5.1.19 * coleofasciculus chthonoplastes 99300.0 1 PMID:25229999 -2.5.1.19 * cylindrospermum licheniforme 84800.0 1 PMID:25229999 -2.5.1.19 * cylindrospermum majus pcc 7604 105500.0 1 PMID:25229999 -2.5.1.19 * desmonostoc muscorum 38000.0 1 PMID:25229999 -2.5.1.19 * dunaliella salina 73000.0 2 PMID:17483801 -2.5.1.19 * escherichia coli 55000.0 6 PMID:18567546;PMID:2824247;PMID:3298979;PMID:6229418;PMID:6351837 -2.5.1.19 * euglena gracilis 159000.0 2 PMID:7808412 -2.5.1.19 * fischerella muscicola 99100.0 1 PMID:25229999 -2.5.1.19 * fischerella thermalis 85600.0 1 PMID:25229999 -2.5.1.19 * gloeobacter violaceus 83000.0 2 PMID:25229999 -2.5.1.19 * gloeothece sp. 98000.0 1 PMID:25229999 -2.5.1.19 * halothermothrix orenii 46020.0 1 PMID:21720820 -2.5.1.19 * janibacter sp. 47000.0 1 PMID:22870190;PMID:25151150;PMID:26754957 -2.5.1.19 * klebsiella pneumoniae 42900.0 3 PMID:6381056 -2.5.1.19 * lathyrus oleraceus 50000.0 2 PMID:24258375 -2.5.1.19 * leptolyngbya boryana 87200.0 1 PMID:25229999 -2.5.1.19 * limnospira fusiformis 111200.0 1 PMID:25229999 -2.5.1.19 * limnospira platensis 91000.0 2 * -2.5.1.19 * lyngbya sp. 82800.0 1 PMID:25229999 -2.5.1.19 * microcystis aeruginosa 79800.0 2 PMID:25229999 -2.5.1.19 * mycobacterium tuberculosis 46458.0 4 PMID:12699693;PMID:18558720 -2.5.1.19 * neurospora crassa 290000.0 1 PMID:4261463 -2.5.1.19 * nostoc punctiforme 46700.0 1 PMID:25229999 -2.5.1.19 * nostoc sp. 83700.0 7 PMID:25229999 -2.5.1.19 * oscillatoria sp. 92500.0 4 PMID:25229999 -2.5.1.19 * pseudomonas aeruginosa 54040.0 2 * -2.5.1.19 * pseudomonas fluorescens 47000.0 3 PMID:17951442;PMID:23090479 -2.5.1.19 * rahnella aquatilis 47000.0 1 PMID:22870190;PMID:25151150;PMID:26754957 -2.5.1.19 * rivularia sp. pcc 7116 86600.0 2 PMID:25229999 -2.5.1.19 * scytonema hofmannii 86700.0 1 PMID:25229999 -2.5.1.19 * sinorhizobium fredii 47000.0 1 PMID:22870190;PMID:25151150;PMID:26754957 -2.5.1.19 * sorghum bicolor 57000.0 1 PMID:16666109 -2.5.1.19 * stanieria sp. pcc 7301 91500.0 1 PMID:25229999 -2.5.1.19 * synechococcus elongatus 100200.0 4 PMID:25229999 -2.5.1.19 * synechococcus sp. 110700.0 5 PMID:25229999 -2.5.1.19 * synechocystis sp. 92200.0 3 PMID:25229999 -2.5.1.19 * tolypothrix sp. 88300.0 1 PMID:25229999 -2.5.1.19 * zea mays 58700.0 4 PMID:12232268 -2.5.1.2 * alosa pseudoharengus 24600.0 1 PMID:36639393 -2.5.1.2 * cheilanthes sieberi 107000.0 1 * -2.5.1.2 * cyprinus carpio 55000.0 2 PMID:10945431;PMID:36639393 -2.5.1.2 * danio rerio 24000.0 1 PMID:36639393 -2.5.1.2 * fistularia petimba 106000.0 1 PMID:19001763 -2.5.1.2 * marsilea drummondii 115000.0 1 * -2.5.1.2 * paenibacillus thiaminolyticus 44000.0 2 PMID:4966932;PMID:8631946 -2.5.1.2 * pteridium esculentum 93000.0 1 * -2.5.1.2 * velesunio ambiguus 110000.0 1 * -2.5.1.20 * euphorbia characias 37000.0 1 PMID:25532121 -2.5.1.20 * hevea brasiliensis 70000.0 4 PMID:2808388 -2.5.1.20 * taraxacum kok-saghyz 34000.0 3 PMID:20170509 -2.5.1.21 * arabidopsis thaliana 47000.0 1 PMID:7892265 -2.5.1.21 * aspergillus flavus 427178.0 1 PMID:30904161 -2.5.1.21 * botryococcus braunii 52500.0 1 PMID:10620354 -2.5.1.21 * bupleurum falcatum 47000.0 1 PMID:21053012 -2.5.1.21 * candida tropicalis 57000.0 2 PMID:24184232;PMID:25764133 -2.5.1.21 * chlamydomonas reinhardtii 57000.0 2 PMID:24184232;PMID:25764133 -2.5.1.21 * chlorophytum borivilianum 46000.0 1 PMID:23338982 -2.5.1.21 * mortierella alpina 46000.0 1 PMID:26275528 -2.5.1.21 * nicotiana tabacum 47000.0 2 PMID:16668616;PMID:9448707 -2.5.1.21 * panax notoginseng 47160.0 1 PMID:27884675 -2.5.1.21 * pinus massoniana 46600.0 1 * -2.5.1.21 * populus trichocarpa 47300.0 1 * -2.5.1.21 * rattus norvegicus 35000.0 1 PMID:1569107 -2.5.1.21 * saccharomyces cerevisiae 68000.0 6 PMID:3277535;PMID:350878;PMID:3805037;PMID:4400077;PMID:7042703;PMID:8323279 -2.5.1.21 * tabernaemontana divaricata 64000.0 2 * -2.5.1.21 * taraxacum kok-saghyz 47981.0 2 PMID:31245726 -2.5.1.21 * taxus cuspidata 46460.0 1 PMID:17927893 -2.5.1.21 * thermosynechococcus vestitus 42000.0 3 PMID:18375558 -2.5.1.21 * trypanosoma cruzi 41670.0 1 PMID:17371809 -2.5.1.21 * withania somnifera 47000.0 2 PMID:22718506;PMID:3277535 -2.5.1.22 * bos taurus 90000.0 2 PMID:520313;PMID:6621388 -2.5.1.22 * gentiana triflora 39000.0 1 PMID:26056006 -2.5.1.22 * homo sapiens 78000.0 4 PMID:18390925;PMID:19859664;PMID:2730590 -2.5.1.22 * lotus japonicus 39700.0 1 PMID:18320213 -2.5.1.23 * hyperthermus butylicus 37000.0 2 PMID:19822146 -2.5.1.23 * saccharolobus solfataricus 112000.0 4 PMID:1541263;PMID:3096734 -2.5.1.24 * dictyostelium discoideum 82000.0 1 * -2.5.1.26 * cavia porcellus 79000.0 3 PMID:8399344;PMID:9266692;PMID:9714777 -2.5.1.26 * suberites domuncula 70585.0 1 * -2.5.1.26 * trypanosoma brucei 68900.0 1 PMID:7619857 -2.5.1.27 * bambusa oldhamii 40000.0 1 * -2.5.1.27 * humulus lupulus 37000.0 1 PMID:15381407 -2.5.1.27 * morus alba 35810.0 1 PMID:17320045 -2.5.1.27 * nostoc sp. 28300.0 4 PMID:26376297 -2.5.1.29 * bacillus subtilis 85000.0 1 PMID:15541397;PMID:6818223 -2.5.1.29 * bos taurus 190000.0 3 PMID:8051156 -2.5.1.29 * capsicum annuum 74000.0 2 * -2.5.1.29 * catharanthus roseus 41600.0 1 PMID:21706164 -2.5.1.29 * corynebacterium glutamicum 158000.0 4 PMID:25181035 -2.5.1.29 * dunaliella salina 38880.0 1 PMID:26289929 -2.5.1.29 * eucommia ulmoides 40000.0 2 PMID:28478108 -2.5.1.29 * geoglobus acetivorans 75000.0 1 PMID:30062607 -2.5.1.29 * homo sapiens 200000.0 1 PMID:16698791 -2.5.1.29 * lutzomyia longipalpis 221000.0 1 PMID:37619821 -2.5.1.29 * megoura viciae 35700.0 1 PMID:36533988 -2.5.1.29 * metarhizium anisopliae 55000.0 1 PMID:19690851 -2.5.1.29 * methanothermobacter thermautotrophicus 78000.0 2 * -2.5.1.29 * micrococcus luteus 70000.0 1 PMID:4021813;PMID:7275954 -2.5.1.29 * monolepta hieroglyphica 35370.0 1 PMID:38349673 -2.5.1.29 * pantoea ananatis 240000.0 2 PMID:18616462 -2.5.1.29 * phycomyces blakesleeanus 60000.0 2 PMID:3190245 -2.5.1.29 * picea abies 40000.0 1 PMID:19939949 -2.5.1.29 * picosynechococcus sp. atcc 27264 61000.0 1 PMID:32523588 -2.5.1.29 * plasmodium falciparum 70000.0 1 PMID:23734739 -2.5.1.29 * ricinus communis 72000.0 1 PMID:10717315 -2.5.1.29 * saccharomyces cerevisiae 82300.0 1 PMID:23534508 -2.5.1.29 * sinapis alba 74000.0 2 PMID:10717315 -2.5.1.29 * solanum lycopersicum 39900.0 2 PMID:16786318 -2.5.1.29 * sulfolobus acidocaldarius 36873.0 2 PMID:16233406;PMID:8182085 -2.5.1.29 * sus scrofa 300000.0 1 PMID:4021812 -2.5.1.29 * synechococcus sp. 61000.0 1 PMID:32523588 -2.5.1.29 * taxus baccata 76000.0 2 PMID:10717315 -2.5.1.29 * taxus canadensis 66000.0 4 PMID:11733504;PMID:9826430 -2.5.1.29 * thermococcus kodakarensis 85000.0 2 PMID:15541397;PMID:6818223 -2.5.1.29 * toxoplasma gondii 61000.0 1 PMID:17724033 -2.5.1.3 * escherichia coli 17000.0 1 PMID:374983;PMID:4580841 -2.5.1.3 * mycobacterium tuberculosis 29000.0 1 PMID:21818324 -2.5.1.3 * saccharomyces cerevisiae 470000.0 4 PMID:18161008;PMID:7982968;PMID:8394314 -2.5.1.3 * zea mays 95000.0 3 PMID:17696876 -2.5.1.30 * bacillus subtilis 45000.0 6 PMID:3927112;PMID:6768722;PMID:9023232;PMID:9748348 -2.5.1.30 * geobacillus stearothermophilus 36172.0 2 PMID:7629164 -2.5.1.31 * bacillus subtilis 85000.0 2 PMID:6818223 -2.5.1.31 * escherichia coli 31000.0 2 PMID:2991704;PMID:3897217;PMID:6712246;PMID:9882662 -2.5.1.31 * haemophilus influenzae 29000.0 1 PMID:9882662 -2.5.1.31 * lactiplantibacillus plantarum 60000.0 6 PMID:2991704;PMID:3897217;PMID:6712246;PMID:8010 -2.5.1.31 * micrococcus luteus 49000.0 4 PMID:11287651;PMID:16900467;PMID:7436416;PMID:9677368 -2.5.1.31 * streptococcus pneumoniae r6 30000.0 1 PMID:9882662 -2.5.1.32 * capsicum annuum 47500.0 1 PMID:16578835 -2.5.1.32 * citrus sinensis 50000.0 2 * -2.5.1.32 * citrus sp. 28000.0 1 * -2.5.1.32 * dunaliella salina 47300.0 1 PMID:15740025 -2.5.1.32 * meiothermus taiwanensis 30600.0 1 * -2.5.1.32 * oryza sativa 43000.0 1 PMID:18326788 -2.5.1.32 * pantoea agglomerans 34500.0 1 PMID:12641468 -2.5.1.32 * salicornia europaea 47200.0 1 PMID:18414806 -2.5.1.32 * solanum lycopersicum 200000.0 3 PMID:10987554;PMID:1164433;PMID:18093;PMID:4021816 -2.5.1.32 * synechococcus sp. 35800.0 1 PMID:1537409 -2.5.1.32 * zea mays 47300.0 2 PMID:18162592 -2.5.1.34 * aspergillus fumigatus 91000.0 7 PMID:15870460;PMID:17577899;PMID:18481055 -2.5.1.34 * claviceps purpurea 105000.0 3 PMID:1605639;PMID:7488077 -2.5.1.34 * claviceps sp. 210000.0 4 PMID:7287742;PMID:999297 -2.5.1.34 * malbranchea aurantiaca 61600.0 3 PMID:18390548 -2.5.1.35 * aspergillus terreus 270000.0 2 PMID:4021817;PMID:678538 -2.5.1.39 * escherichia coli 32510.0 2 PMID:7765507;PMID:8409922 -2.5.1.39 * salvia miltiorrhiza 43790.0 1 PMID:31471635 -2.5.1.41 * methanothermobacter thermautotrophicus 29000.0 1 PMID:8408023 -2.5.1.41 * thermoplasma acidophilum 50000.0 2 PMID:12801917 -2.5.1.42 * saccharolobus solfataricus 28000.0 1 PMID:15356000 -2.5.1.43 * hordeum vulgare 50000.0 3 PMID:9952442 -2.5.1.43 * malus baccata 36200.0 1 * -2.5.1.43 * methanothermobacter thermautotrophicus 60000.0 2 PMID:18931439 -2.5.1.43 * zea mays 65840.0 10 PMID:23455933 -2.5.1.44 * acinetobacter tartarogenes 102000.0 2 PMID:8407874;PMID:8841401 -2.5.1.44 * blastochloris viridis 100000.0 4 PMID:437275;PMID:8407874;PMID:8841401 -2.5.1.44 * lathyrus sativus 75000.0 1 PMID:7470060 -2.5.1.45 * distimake quinquefolius 41300.0 1 PMID:23572540 -2.5.1.45 * ipomoea alba 41500.0 1 PMID:23572540 -2.5.1.45 * ipomoea hederifolia 41600.0 1 PMID:23572540 -2.5.1.45 * ipomoea meyeri 41500.0 1 PMID:23572540 -2.5.1.45 * ipomoea neei 41600.0 1 PMID:23572540 -2.5.1.45 * senecio vernalis 174000.0 4 PMID:10611289;PMID:12562768 -2.5.1.45 * senecio vulgaris 45000.0 2 PMID:11117877 -2.5.1.46 * arabidopsis thaliana 44000.0 2 PMID:16600425;PMID:24904603 -2.5.1.46 * cryptosporidium parvum 180000.0 2 PMID:24893338 -2.5.1.46 * distimake quinquefolius 42100.0 1 PMID:23572540 -2.5.1.46 * homo sapiens 150000.0 3 PMID:12562768;PMID:7673224;PMID:7750572 -2.5.1.46 * ipomoea alba 42300.0 1 PMID:23572540 -2.5.1.46 * ipomoea hederifolia 42300.0 1 PMID:23572540 -2.5.1.46 * ipomoea meyeri 42200.0 1 PMID:23572540 -2.5.1.46 * ipomoea neei 42200.0 1 PMID:23572540 -2.5.1.46 * leishmania donovani 137000.0 6 PMID:19880510 -2.5.1.46 * neurospora crassa 180000.0 2 PMID:7592594 -2.5.1.46 * nicotiana tabacum 190000.0 2 PMID:10542236 -2.5.1.46 * rattus norvegicus 190000.0 3 PMID:2108161;PMID:7721768 -2.5.1.46 * saccharolobus solfataricus 144000.0 1 PMID:30047030 -2.5.1.46 * saccharomyces cerevisiae 172000.0 3 PMID:16215987;PMID:7629166;PMID:9163530 -2.5.1.46 * senecio vernalis 41000.0 1 PMID:12562768;PMID:7673224 -2.5.1.46 * theileria parva 41260.0 2 PMID:24909679 -2.5.1.46 * trichomonas vaginalis 170000.0 2 PMID:26410361 -2.5.1.46 * triticum aestivum 41400.0 1 PMID:21463208 -2.5.1.47 * acidithiobacillus ferrooxidans 32000.0 1 PMID:20033172 -2.5.1.47 * aeropyrum pernix 70580.0 2 PMID:12644499 -2.5.1.47 * allium tuberosum 81000.0 4 * -2.5.1.47 * allochromatium vinosum 56000.0 2 * -2.5.1.47 * arabidopsis thaliana 300000.0 2 PMID:9692924 -2.5.1.47 * brassica juncea 52000.0 2 PMID:9729892 -2.5.1.47 * capsicum annuum 35000.0 1 PMID:1375015;PMID:1381358;PMID:8424655;PMID:8617276 -2.5.1.47 * chlamydomonas reinhardtii 65000.0 1 * -2.5.1.47 * chlorella sorokiniana 33800.0 2 PMID:25093930 -2.5.1.47 * citrullus lanatus 58000.0 2 PMID:6373737 -2.5.1.47 * corynebacterium glutamicum 70800.0 2 PMID:15277766 -2.5.1.47 * datura inoxia 86000.0 5 PMID:8119966 -2.5.1.47 * enterobacter sp. 68000.0 2 PMID:12005048;PMID:16233442;PMID:4891157;PMID:7669816;PMID:9571779 -2.5.1.47 * escherichia coli 64000.0 3 PMID:15952768;PMID:16546401 -2.5.1.47 * geobacillus stearothermophilus 70000.0 4 PMID:12005048;PMID:15308337;PMID:16233442;PMID:19213732;PMID:4891157;PMID:7669816;PMID:9571779 -2.5.1.47 * glycine max 74200.0 10 PMID:16233442;PMID:19213732 -2.5.1.47 * lacticaseibacillus casei 34900.0 2 PMID:22113557 -2.5.1.47 * lathyrus oleraceus 52000.0 2 PMID:9729892 -2.5.1.47 * leishmania donovani 72000.0 1 PMID:27638321 -2.5.1.47 * leishmania major 35600.0 1 PMID:22750854 -2.5.1.47 * leucaena leucocephala 40000.0 2 PMID:24777760 -2.5.1.47 * methanosarcina thermophila 93000.0 3 PMID:10613861 -2.5.1.47 * monascus purpureus 57044.0 1 * -2.5.1.47 * penicillium chrysogenum 68000.0 2 * -2.5.1.47 * raphanus sativus 66000.0 2 * -2.5.1.47 * rhodocyclus tenuis 57000.0 2 PMID:6615127 -2.5.1.47 * saccharomyces cerevisiae 200000.0 4 PMID:7007360;PMID:795807 -2.5.1.47 * salmonella enterica subsp. enterica serovar typhimurium 1390000.0 7 PMID:12005048;PMID:16233442;PMID:359557;PMID:4891157;PMID:6373737;PMID:7669816;PMID:9571779 -2.5.1.47 * spinacia oleracea 310000.0 9 PMID:12005048;PMID:1375015;PMID:1381358;PMID:15308337;PMID:16233442;PMID:4891157;PMID:7669816;PMID:8424655;PMID:8617276;PMID:9571779 -2.5.1.47 * streptomyces lavendulae 126000.0 2 PMID:23529730 -2.5.1.47 * synechococcus sp. 56000.0 1 * -2.5.1.47 * thermus thermophilus 68000.0 2 PMID:12005048;PMID:16233442;PMID:4891157;PMID:7669816;PMID:9571779 -2.5.1.47 * xanthium pennsylvanicum 52000.0 1 PMID:9729892 -2.5.1.48 * arabidopsis thaliana 56000.0 1 PMID:16507086 -2.5.1.48 * corynebacterium glutamicum 41655.0 1 PMID:10420990 -2.5.1.48 * escherichia coli 160000.0 5 PMID:2405903;PMID:6361021 -2.5.1.48 * lysinibacillus sphaericus 165000.0 2 PMID:3816790 -2.5.1.48 * mycobacterium tuberculosis 160000.0 2 PMID:19428471 -2.5.1.48 * saccharomyces cerevisiae 194000.0 3 PMID:8335636;PMID:8511969 -2.5.1.48 * salmonella enterica subsp. enterica serovar typhimurium 160000.0 1 PMID:2405903 -2.5.1.48 * spinacia oleracea 215000.0 3 PMID:7840669 -2.5.1.48 * sulfurisphaera tokodaii 150000.0 1 PMID:28291751 -2.5.1.49 * [brevibacterium] flavum 360000.0 1 PMID:7096282 -2.5.1.49 * aspergillus nidulans 267000.0 3 PMID:8249501 -2.5.1.49 * clostridioides difficile 180000.0 2 PMID:16233482;PMID:31359602 -2.5.1.49 * corynebacterium acetophilum 220000.0 2 PMID:15989 -2.5.1.49 * geobacillus stearothermophilus 180000.0 3 PMID:16233482;PMID:31359602 -2.5.1.49 * saccharomyces cerevisiae 480000.0 7 PMID:4947307;PMID:7007360;PMID:795807 -2.5.1.49 * schizosaccharomyces pombe 186000.0 2 PMID:6526818 -2.5.1.49 * selenomonas ruminantium 34670.0 1 PMID:15057458 -2.5.1.49 * thermus thermophilus 190000.0 7 PMID:11566369;PMID:15215603 -2.5.1.5 * betaphycus gelatinus 65000.0 1 PMID:24632215 -2.5.1.50 * lupinus luteus 64500.0 1 * -2.5.1.51 * citrullus lanatus 58000.0 2 * -2.5.1.52 * leucaena leucocephala 64000.0 2 * -2.5.1.53 * lathyrus oleraceus 50000.0 1 * -2.5.1.54 * aeropyrum pernix 55400.0 3 PMID:22035970 -2.5.1.54 * amycolatopsis mediterranei 135000.0 2 PMID:2565737 -2.5.1.54 * bacillus subtilis 156000.0 1 PMID:15869469 -2.5.1.54 * corynebacterium glutamicum 84000.0 4 PMID:18621870 -2.5.1.54 * daucus carota 400000.0 4 PMID:16664489 -2.5.1.54 * delftia acidovorans 251000.0 2 PMID:2859843 -2.5.1.54 * escherichia coli 140000.0 14 PMID:11506923;PMID:12951;PMID:16665132;PMID:1672127;PMID:26682;PMID:30946901;PMID:9387 -2.5.1.54 * helicobacter pylori 100000.0 2 PMID:15853768 -2.5.1.54 * kitasatospora aureofaciens 97000.0 1 PMID:5003718 -2.5.1.54 * mycobacterium tuberculosis 253000.0 7 PMID:15721768;PMID:19556970;PMID:19851019 -2.5.1.54 * neisseria meningitidis 150000.0 3 PMID:26828675 -2.5.1.54 * neurospora crassa 200000.0 3 PMID:16665132;PMID:6119978 -2.5.1.54 * oryza sativa 59000.0 1 * -2.5.1.54 * pseudomonas aeruginosa 175000.0 2 PMID:6127340 -2.5.1.54 * pyrococcus furiosus 111000.0 6 PMID:14766297;PMID:24239948 -2.5.1.54 * saccharomyces cerevisiae 53000.0 3 PMID:2574670;PMID:9575238 -2.5.1.54 * salmonella enterica subsp. enterica serovar typhimurium 100000.0 3 PMID:12135;PMID:4572729 -2.5.1.54 * solanum tuberosum 110000.0 2 PMID:12951;PMID:16665132 -2.5.1.54 * spinacia oleracea 443000.0 1 * -2.5.1.54 * streptomyces coelicolor 107000.0 2 PMID:16665132 -2.5.1.54 * streptomyces rimosus 120000.0 3 PMID:16665132;PMID:8094298 -2.5.1.54 * thermotoga maritima 134000.0 2 PMID:12743122 -2.5.1.55 * aquifex aeolicus 97600.0 2 PMID:10491295 -2.5.1.55 * arabidopsis thaliana 76000.0 3 PMID:15070398;PMID:24993790 -2.5.1.55 * campylobacter jejuni 123000.0 1 PMID:30125100 -2.5.1.55 * chlamydia psittaci 30000.0 2 PMID:9063447 -2.5.1.55 * escherichia coli 123400.0 9 PMID:6988389;PMID:7048004;PMID:7775423 -2.5.1.55 * helicobacter pylori 121800.0 10 PMID:19399763;PMID:26649906 -2.5.1.55 * neisseria meningitidis 130000.0 3 PMID:18930408;PMID:19447118 -2.5.1.55 * salmonella enterica subsp. enterica serovar typhimurium 97000.0 1 PMID:10913123 -2.5.1.56 * campylobacter jejuni 43300.0 1 PMID:15200387 -2.5.1.56 * escherichia coli 160000.0 5 PMID:12083785;PMID:15734325;PMID:9438985 -2.5.1.56 * idiomarina loihiensis 95000.0 3 PMID:25214154 -2.5.1.56 * moritella viscosa 74000.0 2 PMID:25498013 -2.5.1.56 * neisseria meningitidis 78000.0 6 PMID:16274664 -2.5.1.56 * streptococcus agalactiae 160000.0 3 PMID:12597896;PMID:15734325 -2.5.1.57 * drosophila melanogaster 41000.0 1 PMID:11886840 -2.5.1.57 * homo sapiens 100100.0 9 PMID:16274664;PMID:16729195;PMID:18304454;PMID:18326787 -2.5.1.57 * mus musculus 80000.0 3 PMID:10873658 -2.5.1.57 * rattus norvegicus 75000.0 2 PMID:11886839 -2.5.1.58 * bos taurus 100000.0 1 PMID:8883388 -2.5.1.58 * entamoeba histolytica 80000.0 5 PMID:14583615 -2.5.1.58 * homo sapiens 270000.0 6 PMID:16477080;PMID:28948621 -2.5.1.58 * rattus norvegicus 487000.0 10 PMID:10325405;PMID:26551458;PMID:8419339;PMID:8486655;PMID:8621375;PMID:9434909 -2.5.1.58 * saccharomyces cerevisiae 90000.0 7 PMID:26551458;PMID:8424764;PMID:8486655;PMID:8621375;PMID:9434909 -2.5.1.58 * solanum lycopersicum 100000.0 1 PMID:8883388 -2.5.1.58 * trypanosoma brucei brucei 65000.0 2 PMID:9756885 -2.5.1.59 * bos taurus 48000.0 2 PMID:8440698 -2.5.1.59 * candida albicans 82000.0 3 PMID:18713740 -2.5.1.59 * homo sapiens 48000.0 2 PMID:25450772 -2.5.1.59 * rattus norvegicus 48000.0 4 PMID:16477080;PMID:25450772 -2.5.1.59 * saccharomyces cerevisiae 48000.0 4 PMID:7639519;PMID:8621375 -2.5.1.59 * trypanosoma cruzi 42000.0 1 PMID:17996962 -2.5.1.6 * bacillus subtilis 180000.0 2 PMID:18634909;PMID:6251075 -2.5.1.6 * bos taurus 160000.0 3 PMID:3403522 -2.5.1.6 * catharanthus roseus 43050.0 3 PMID:9037140 -2.5.1.6 * corynebacterium glutamicum 44100.0 2 PMID:24154832;PMID:26238196 -2.5.1.6 * crypthecodinium cohnii 50500.0 1 PMID:17915037 -2.5.1.6 * cryptobia salmositica 37850.0 1 PMID:17226041 -2.5.1.6 * cryptosporidium parvum 44800.0 1 PMID:12951252 -2.5.1.6 * escherichia coli 180000.0 5 PMID:18634909;PMID:24154832;PMID:26238196;PMID:6137755;PMID:6251075;PMID:6343384 -2.5.1.6 * homo sapiens 185000.0 7 PMID:10644686;PMID:3980460;PMID:7665609;PMID:7803470 -2.5.1.6 * lactiplantibacillus paraplantarum 43000.0 1 PMID:24154832;PMID:26238196 -2.5.1.6 * leishmania donovani 48000.0 1 PMID:12492472 -2.5.1.6 * leishmania infantum 249000.0 2 PMID:11698393 -2.5.1.6 * methanocaldococcus jannaschii 86000.0 3 PMID:11872742;PMID:21132339 -2.5.1.6 * pneumocystis carinii 45000.0 1 PMID:18065654 -2.5.1.6 * pneumocystis jirovecii 45000.0 1 PMID:18065654 -2.5.1.6 * pneumocystis murina 45000.0 1 PMID:18065654 -2.5.1.6 * pyrococcus furiosus 90000.0 3 PMID:25577347 -2.5.1.6 * rattus norvegicus 210000.0 28 PMID:10873534;PMID:12496263;PMID:18560753;PMID:3093473;PMID:3121322;PMID:6621386;PMID:6849873;PMID:7213623 -2.5.1.6 * saccharolobus solfataricus 180000.0 4 PMID:3142771 -2.5.1.6 * saccharomyces cerevisiae 110000.0 4 PMID:194884 -2.5.1.6 * streptomyces avermitilis 43500.0 1 * -2.5.1.6 * streptomyces coelicolor 46000.0 1 PMID:12511507 -2.5.1.6 * streptomyces peucetius 43000.0 2 PMID:20163498 -2.5.1.6 * streptomyces spectabilis 42000.0 1 PMID:17334759 -2.5.1.6 * streptomyces xinghaiensis 43000.0 2 PMID:34489034 -2.5.1.6 * sus scrofa 37640.0 1 PMID:19701798 -2.5.1.6 * thermococcus kodakarensis 44300.0 1 PMID:24134203 -2.5.1.6 * thermus thermophilus 45000.0 2 * -2.5.1.6 * trypanosoma brucei brucei 145000.0 1 PMID:8457607 -2.5.1.60 * mus musculus 38000.0 1 PMID:18161010 -2.5.1.60 * rattus norvegicus 100000.0 3 PMID:11388804;PMID:1321151;PMID:8621375 -2.5.1.60 * saccharomyces cerevisiae 60000.0 2 PMID:1321151;PMID:8621375 -2.5.1.61 * arabidopsis thaliana 35000.0 2 * -2.5.1.61 * cereibacter sphaeroides 39000.0 5 PMID:4539746;PMID:4542566 -2.5.1.61 * chlorella regularis 36000.0 2 PMID:7213640 -2.5.1.61 * escherichia coli 39100.0 3 PMID:1548705;PMID:3548707;PMID:8436121 -2.5.1.61 * euglena gracilis 41000.0 2 PMID:2477247;PMID:6796041 -2.5.1.61 * felis catus 43000.0 3 PMID:19934113 -2.5.1.61 * homo sapiens 68000.0 17 PMID:17298218;PMID:1925827;PMID:19292878;PMID:23815679;PMID:2609111;PMID:3390155;PMID:42911;PMID:4847568;PMID:7354069;PMID:7682572 -2.5.1.61 * lathyrus oleraceus 45000.0 1 PMID:1986793 -2.5.1.61 * nitratidesulfovibrio vulgaris 38000.0 1 PMID:19267692 -2.5.1.61 * plasmodium falciparum 45000.0 2 PMID:17962188 -2.5.1.61 * rattus norvegicus 43000.0 3 PMID:6712591;PMID:6796041;PMID:9344466 -2.5.1.61 * spinacia oleracea 40000.0 2 PMID:7213640 -2.5.1.61 * tetradesmus obliquus 33000.0 1 * -2.5.1.62 * hordeum vulgare 30000.0 1 PMID:26172838 -2.5.1.62 * nicotiana tabacum 40000.0 2 PMID:19680747 -2.5.1.62 * triticum aestivum 41100.0 1 PMID:18071923 -2.5.1.63 * nocardia brasiliensis 200000.0 2 PMID:24795808 -2.5.1.63 * streptantibioticus cattleyicolor 180000.0 4 PMID:12860396;PMID:14765200;PMID:24795808 -2.5.1.65 * aeropyrum pernix 70580.0 3 PMID:12644499;PMID:12965218 -2.5.1.66 * streptomyces clavuligerus 240000.0 5 PMID:14623876;PMID:14982786 -2.5.1.67 * tanacetum cinerariifolium 66000.0 4 PMID:11287653 -2.5.1.68 * corynebacterium efficiens 31000.0 1 PMID:18725204 -2.5.1.68 * corynebacterium glutamicum 31000.0 1 PMID:18725204 -2.5.1.68 * thermobifida fusca 31000.0 1 PMID:18725204 -2.5.1.69 * lavandula x intermedia 34500.0 1 PMID:23306202 -2.5.1.7 * acinetobacter baumannii 45000.0 1 PMID:28064057 -2.5.1.7 * aliivibrio fischeri 45640.0 2 PMID:19277606;PMID:22505403 -2.5.1.7 * enterobacter cloacae 44780.0 7 PMID:10413459;PMID:1123336;PMID:1577165;PMID:24317075 -2.5.1.7 * escherichia coli 89000.0 4 PMID:1512209;PMID:24317075;PMID:35819545 -2.5.1.7 * fusobacterium nucleatum subsp. nucleatum 48000.0 1 PMID:28358152 -2.5.1.7 * haemophilus influenzae 46300.0 3 PMID:15995357;PMID:23462005 -2.5.1.7 * mycobacterium tuberculosis 45500.0 1 PMID:24463011 -2.5.1.7 * mycolicibacterium smegmatis 45430.0 1 PMID:24463011 -2.5.1.7 * pseudomonas aeruginosa 89000.0 1 * -2.5.1.7 * wolbachia sp. 51000.0 1 PMID:24941309 -2.5.1.72 * bacillus subtilis 124000.0 2 PMID:18959769 -2.5.1.72 * cyanophora paradoxa 36760.0 1 PMID:16667973 -2.5.1.72 * escherichia coli 80000.0 7 PMID:10648170;PMID:15967443;PMID:18674537 -2.5.1.73 * methanosarcina mazei 84000.0 3 PMID:18559341 -2.5.1.74 * mylabris cichorii 37900.0 1 PMID:25772016 -2.5.1.75 * escherichia coli 55000.0 3 PMID:4346747;PMID:9012675 -2.5.1.75 * malus hupehensis 37300.0 1 PMID:18381270 -2.5.1.75 * physcomitrium patens 62000.0 1 PMID:17450376 -2.5.1.75 * zea mays 60000.0 1 PMID:342386 -2.5.1.76 * methanosarcina acetivorans 132000.0 2 PMID:19761441 -2.5.1.78 * brucella abortus 80100.0 2 PMID:17854827 -2.5.1.78 * brucella melitensis 75300.0 2 PMID:17854827 -2.5.1.78 * brucella sp. 234000.0 6 PMID:10482294;PMID:14660615;PMID:16923880;PMID:23918978 -2.5.1.78 * escherichia coli 977000.0 2 PMID:8969176 -2.5.1.78 * lycium chinense 25410.0 2 * -2.5.1.78 * mesorhizobium loti 158500.0 4 PMID:17854827 -2.5.1.78 * methanocaldococcus jannaschii 16000.0 2 PMID:12603336 -2.5.1.78 * momordica charantia 23230.0 1 PMID:23153065 -2.5.1.78 * nakaseomyces glabratus 97770.0 1 PMID:23897480 -2.5.1.78 * paracoccidioides brasiliensis 19000.0 1 PMID:19500685 -2.5.1.78 * saccharomyces cerevisiae 90000.0 3 PMID:7559556;PMID:8969176 -2.5.1.78 * salmonella enterica subsp. enterica serovar typhimurium 18100.0 2 PMID:21245535 -2.5.1.78 * schizosaccharomyces pombe 87000.0 3 PMID:11856310 -2.5.1.78 * spinacia oleracea 991000.0 5 PMID:10419541 -2.5.1.79 * gossypium hirsutum 38420.0 1 PMID:26209974 -2.5.1.79 * thalassiosira pseudonana 200000.0 5 PMID:17560575;PMID:19075322 -2.5.1.80 * aspergillus fumigatus 65000.0 4 PMID:17906140;PMID:18481055 -2.5.1.80 * aspergillus niger 228000.0 3 PMID:24970457 -2.5.1.80 * neosartorya sp. 53000.0 2 PMID:24657051 -2.5.1.81 * methanosarcina mazei 48900.0 3 PMID:20097171;PMID:21586277 -2.5.1.81 * natronomonas pharaonis 76000.0 1 PMID:8137956 -2.5.1.82 * saccharolobus solfataricus 32274.0 2 PMID:11790729 -2.5.1.83 * micrococcus luteus 60000.0 3 PMID:2541701;PMID:7174655 -2.5.1.84 * micrococcus luteus 78000.0 3 PMID:1748647;PMID:4021815;PMID:911777 -2.5.1.85 * arabidopsis thaliana 108000.0 3 PMID:12437513;PMID:15784989 -2.5.1.85 * hevea brasiliensis 60000.0 1 * -2.5.1.85 * trypanosoma brucei 39200.0 2 PMID:22406034;PMID:24376001 -2.5.1.85 * trypanosoma cruzi 39000.0 1 PMID:17062572 -2.5.1.86 * mycobacterium tuberculosis 36000.0 1 PMID:15516568 -2.5.1.87 * arabidopsis thaliana 33000.0 1 PMID:10764783 -2.5.1.87 * candida albicans 37000.0 1 PMID:24875421 -2.5.1.87 * lilium longiflorum 35700.0 2 PMID:21757455 -2.5.1.87 * oncorhynchus mykiss 38410.0 1 PMID:19103300 -2.5.1.9 * arabidopsis thaliana 75000.0 3 PMID:11399071;PMID:15927885;PMID:16042598 -2.5.1.9 * bacillus subtilis 100000.0 7 PMID:2106516;PMID:3084909;PMID:3100522;PMID:3145341;PMID:6766130 -2.5.1.9 * brucella abortus 69800.0 3 PMID:24816110;PMID:30927485 -2.5.1.9 * escherichia coli 75000.0 3 PMID:11377200;PMID:11399071;PMID:12927541;PMID:16042598 -2.5.1.9 * geobacillus stearothermophilus 345000.0 1 PMID:25043 -2.5.1.9 * leptospira kmetyi 69000.0 2 * -2.5.1.9 * methanocaldococcus jannaschii 88300.0 4 PMID:15381435 -2.5.1.9 * momordica charantia 30670.0 1 PMID:23153065 -2.5.1.9 * saccharomyces cerevisiae 80000.0 1 * -2.5.1.9 * schizosaccharomyces pombe 23000.0 1 PMID:14690539 -2.5.1.9 * streptomyces davaonensis 22000.0 1 PMID:17541777 -2.5.1.90 * plasmodium falciparum 63000.0 1 PMID:15984931 -2.5.1.91 * agrobacterium tumefaciens 71000.0 5 PMID:14763823;PMID:17401144;PMID:19508223 -2.5.1.91 * aphis gossypii 46150.0 2 PMID:24246678 -2.5.1.91 * cereibacter sphaeroides 38100.0 2 PMID:16896603 -2.5.1.91 * gluconobacter oxydans 41000.0 2 PMID:9692900 -2.5.1.91 * paracoccus denitrificans 60000.0 1 * -2.5.1.91 * rhodobacter capsulatus 37000.0 1 PMID:17473883 -2.5.1.91 * schizosaccharomyces pombe 42047.0 4 PMID:14519123 -2.5.1.91 * solanum lycopersicum 45443.0 1 PMID:23126257 -2.5.1.92 * plasmodium falciparum 70000.0 1 PMID:23734739 -2.5.1.92 * solanum habrochaites 28000.0 1 PMID:19155349 -2.5.1.93 * lithospermum erythrorhizon 341000.0 2 PMID:9640665 -2.5.1.94 * salinispora tropica cnb-440 30000.0 1 PMID:18059261 -2.5.1.96 * lactiplantibacillus plantarum 33419.0 1 PMID:20303609 -2.5.1.96 * staphylococcus aureus 30121.0 1 PMID:8002598 -2.5.1.97 * campylobacter jejuni 38670.0 2 PMID:16120604 -2.6.1.1 * arabidopsis thaliana 53000.0 2 PMID:16623902 -2.6.1.1 * avena sativa 130000.0 1 PMID:1141216 -2.6.1.1 * bacillus sp. (in: firmicutes) 98000.0 2 PMID:12723595;PMID:2155199;PMID:2930193 -2.6.1.1 * bacillus subtilis 55000.0 2 PMID:21332942 -2.6.1.1 * bos taurus 103000.0 3 PMID:446759;PMID:4708676 -2.6.1.1 * bradyrhizobium japonicum 100000.0 1 PMID:2332417;PMID:2930193;PMID:3879173 -2.6.1.1 * bubalus bubalis 46410.0 2 * -2.6.1.1 * chlamydomonas reinhardtii 138000.0 2 PMID:2331983 -2.6.1.1 * cupriavidus necator 43000.0 1 PMID:22797525 -2.6.1.1 * cystobasidium minutum 100000.0 5 PMID:2332417;PMID:2930193;PMID:3879173 -2.6.1.1 * daucus carota 111000.0 1 PMID:16668442 -2.6.1.1 * eleusine coracana 80000.0 2 PMID:2241160;PMID:32738436 -2.6.1.1 * escherichia coli 87000.0 6 PMID:17425331;PMID:236311;PMID:3003515;PMID:374118 -2.6.1.1 * geobacillus thermopakistaniensis 80000.0 1 PMID:2241160;PMID:32738436 -2.6.1.1 * glycine max 100000.0 1 PMID:2332417;PMID:2930193;PMID:3879173 -2.6.1.1 * haloferax mediterranei 68200.0 2 * -2.6.1.1 * hyalomma dromedarii 52000.0 2 PMID:11523919 -2.6.1.1 * leptosphaeria michotii 92000.0 1 PMID:2707258 -2.6.1.1 * lupinus albus 136000.0 6 PMID:12297033 -2.6.1.1 * lupinus angustifolius 105000.0 2 PMID:7294808 -2.6.1.1 * magallana gigas 45300.0 1 PMID:15792625 -2.6.1.1 * medicago sativa 80000.0 2 PMID:16666973 -2.6.1.1 * megathyrsus maximus 100000.0 2 PMID:12723595;PMID:2155199;PMID:2332417;PMID:2930193;PMID:3879173 -2.6.1.1 * methanococcus aeolicus 162000.0 1 PMID:1729242 -2.6.1.1 * methanothermobacter thermautotrophicus 180000.0 4 PMID:11523919;PMID:1295891 -2.6.1.1 * mycobacterium tuberculosis 42035.0 1 * -2.6.1.1 * oryctolagus cuniculus 94000.0 4 PMID:4030726 -2.6.1.1 * oryza sativa 94000.0 7 PMID:16623902;PMID:2332417 -2.6.1.1 * ovis aries 88900.0 3 PMID:35156;PMID:4204952 -2.6.1.1 * phormidium lapideum 85000.0 2 PMID:12723595;PMID:2155199;PMID:2930193 -2.6.1.1 * pinus pinaster 120000.0 3 PMID:1445947;PMID:16623902 -2.6.1.1 * pseudoalteromonas haloplanktis 43776.0 1 PMID:10785402 -2.6.1.1 * pseudomonas putida 80000.0 1 PMID:1290 -2.6.1.1 * rattus norvegicus 98000.0 9 PMID:11051104;PMID:16489927;PMID:16631106;PMID:7426616;PMID:7878064 -2.6.1.1 * saccharolobus solfataricus 120000.0 7 PMID:1445947;PMID:16623902;PMID:2513189;PMID:3137225;PMID:8026489 -2.6.1.1 * saccharomyces cerevisiae 92000.0 2 PMID:6811576 -2.6.1.1 * staphylococcus aureus 48170.0 1 PMID:17565195 -2.6.1.1 * sus scrofa 93150.0 3 PMID:11946901;PMID:1278171 -2.6.1.1 * torulopsis candida 95000.0 2 PMID:2332417 -2.6.1.1 * trichomonas vaginalis 100000.0 2 PMID:2332417;PMID:2930193;PMID:3879173 -2.6.1.1 * triticum aestivum 72400.0 4 * -2.6.1.100 * niallia circulans 97000.0 4 PMID:12478783 -2.6.1.101 * streptomyces fradiae 46951.0 3 PMID:15827636 -2.6.1.102 * escherichia coli 458000.0 3 PMID:17888872;PMID:18201574 -2.6.1.102 * vibrio cholerae serotype o1 170000.0 2 PMID:11479276 -2.6.1.103 * amycolatopsis orientalis 49800.0 1 * -2.6.1.11 * arabidopsis thaliana 48800.0 1 PMID:23321422 -2.6.1.11 * chlamydomonas reinhardtii 48000.0 1 PMID:19617392 -2.6.1.11 * corynebacterium glutamicum 41000.0 1 PMID:22016985 -2.6.1.11 * escherichia coli 119000.0 4 PMID:112925;PMID:4599318 -2.6.1.11 * klebsiella aerogenes 59000.0 2 PMID:24039 -2.6.1.11 * pseudomonas aeruginosa 105000.0 2 PMID:238949 -2.6.1.110 * saccharopolyspora spinosa 85900.0 3 PMID:18345667 -2.6.1.111 * candidatus cloacimonas acidaminovorans 93000.0 1 PMID:21826218 -2.6.1.118 * thermus thermophilus 80000.0 1 PMID:11489859 -2.6.1.120 * lachancea kluyveri 111000.0 1 PMID:17355287 -2.6.1.120 * rattus norvegicus 105000.0 2 PMID:3085724;PMID:6816789 -2.6.1.120 * streptomyces griseus 185000.0 1 PMID:3972825 -2.6.1.125 * pimelobacter simplex 110000.0 1 PMID:7426667 -2.6.1.13 * agaricus bisporus 50700.0 1 PMID:17703933 -2.6.1.13 * bacillus sp. (in: firmicutes) 82000.0 2 PMID:7287630;PMID:8537297 -2.6.1.13 * bos taurus 88000.0 3 PMID:7238632 -2.6.1.13 * brevibacillus brevis 90000.0 1 * -2.6.1.13 * clavibacter sepedonicus 180000.0 1 * -2.6.1.13 * cucurbita pepo 48000.0 1 PMID:16659110 -2.6.1.13 * gallus gallus 63000.0 2 * -2.6.1.13 * homo sapiens 183000.0 4 PMID:11465067;PMID:28345116;PMID:6819292 -2.6.1.13 * lathyrus oleraceus 50000.0 1 PMID:20381578 -2.6.1.13 * lysinibacillus sphaericus 85000.0 2 PMID:7287630;PMID:8537297 -2.6.1.13 * manduca sexta 152000.0 2 PMID:2295622 -2.6.1.13 * mus musculus 92000.0 4 PMID:17341717;PMID:3364978;PMID:9873834 -2.6.1.13 * pinus sylvestris 51200.0 2 PMID:18621980 -2.6.1.13 * plasmodium falciparum 109000.0 2 PMID:11704268 -2.6.1.13 * rattus norvegicus 256000.0 7 PMID:1268231;PMID:3364978;PMID:3803391;PMID:5783831 -2.6.1.13 * toxoplasma gondii 77000.0 1 PMID:28126740 -2.6.1.13 * vigna aconitifolia 50000.0 2 PMID:17604199;PMID:19513195 -2.6.1.14 * mus musculus 70800.0 1 PMID:3099645 -2.6.1.15 * rattus norvegicus 110000.0 2 PMID:12850267;PMID:5059882 -2.6.1.16 * bifidobacterium longum 69600.0 3 PMID:17943273 -2.6.1.16 * bos taurus 350000.0 1 * -2.6.1.16 * candida albicans 340000.0 8 PMID:16169745;PMID:16511216;PMID:17309446;PMID:23108616 -2.6.1.16 * escherichia coli 193000.0 4 PMID:11700065;PMID:20416269;PMID:3297136 -2.6.1.16 * haemaphysalis longicornis 78400.0 1 PMID:17222844 -2.6.1.16 * homo sapiens 77000.0 1 PMID:1460020 -2.6.1.16 * rattus norvegicus 410000.0 4 PMID:10898949;PMID:1247593 -2.6.1.16 * saccharomyces cerevisiae 320000.0 3 PMID:22125025;PMID:24930098 -2.6.1.16 * sporothrix schenckii 79000.0 1 PMID:25514203 -2.6.1.16 * vigna radiata var. radiata 300000.0 1 PMID:16658095 -2.6.1.16 * volvariella volvacea 310000.0 3 PMID:19165584 -2.6.1.17 * escherichia coli 82000.0 2 * -2.6.1.18 * chromobacterium violaceum 100000.0 2 PMID:17277454 -2.6.1.18 * pseudomonas aeruginosa 43000.0 1 PMID:16902948 -2.6.1.19 * bos taurus 53950.0 2 PMID:11561735 -2.6.1.19 * candida guilliermondii var. membranaefaciens 107000.0 1 PMID:3699025 -2.6.1.19 * cupriavidus necator 120000.0 2 PMID:19648235 -2.6.1.19 * homo sapiens 100000.0 4 PMID:11459221;PMID:15528998;PMID:15650327;PMID:623769 -2.6.1.19 * lachancea kluyveri 111000.0 4 PMID:17355287 -2.6.1.19 * malus domestica 54200.0 2 * -2.6.1.19 * meriones unguiculatus 50000.0 1 PMID:11459221;PMID:15650327 -2.6.1.19 * mus musculus 109000.0 3 PMID:4156051;PMID:4719123 -2.6.1.19 * oryza sativa 56474.0 2 PMID:16896530 -2.6.1.19 * ovis aries 97000.0 2 PMID:3355498;PMID:3917915 -2.6.1.19 * paenibacillus lautus 200000.0 1 PMID:31921013 -2.6.1.19 * pseudomonas aeruginosa 200000.0 1 PMID:825509 -2.6.1.19 * pseudomonas sp. 178000.0 1 PMID:7362249 -2.6.1.19 * rattus norvegicus 107000.0 7 PMID:10447691;PMID:11459221;PMID:1164912;PMID:15650327;PMID:23842;PMID:4447797;PMID:623769 -2.6.1.19 * schistocerca gregaria 97000.0 1 PMID:3355498 -2.6.1.19 * streptomyces griseus 100000.0 2 PMID:3355498;PMID:3917915 -2.6.1.19 * sus scrofa 110100.0 4 PMID:1164912;PMID:23842;PMID:2388271;PMID:4447797 -2.6.1.2 * bombyx mori 69000.0 1 * -2.6.1.2 * bos taurus 92000.0 1 PMID:4065923 -2.6.1.2 * branchiostoma belcheri 101000.0 1 PMID:17002870 -2.6.1.2 * candida maltosa 99000.0 2 PMID:7764540 -2.6.1.2 * canis lupus familiaris 118000.0 3 PMID:16495081;PMID:590935 -2.6.1.2 * capsicum annuum 53000.0 1 PMID:15782348 -2.6.1.2 * chlamydomonas reinhardtii 105000.0 2 PMID:1662617 -2.6.1.2 * clarias batrachus 56000.0 2 PMID:14990216 -2.6.1.2 * felis catus 118000.0 1 PMID:590935 -2.6.1.2 * homo sapiens 118000.0 4 PMID:18508279;PMID:19545238;PMID:590935 -2.6.1.2 * hordeum vulgare 97000.0 2 PMID:16669068;PMID:1898070 -2.6.1.2 * hydrogenobacter thermophilus 69000.0 2 PMID:20214682 -2.6.1.2 * kluyveromyces lactis 135900.0 1 PMID:28694796 -2.6.1.2 * labeo rohita 56000.0 2 PMID:14990216 -2.6.1.2 * lachancea kluyveri 111000.0 5 PMID:17355287;PMID:28694796 -2.6.1.2 * leptosphaeria michotii 110000.0 1 * -2.6.1.2 * medicago truncatula 57900.0 1 PMID:16899523 -2.6.1.2 * oryctolagus cuniculus 118000.0 3 PMID:6816789 -2.6.1.2 * panicum miliaceum 102000.0 2 PMID:16669068;PMID:1898070 -2.6.1.2 * pyrococcus furiosus 93400.0 2 PMID:10762259 -2.6.1.2 * rattus norvegicus 115000.0 8 PMID:15663181;PMID:590935 -2.6.1.2 * saccharomyces cerevisiae 147000.0 1 PMID:29867852 -2.6.1.2 * sogatella furcifera 59840.0 2 * -2.6.1.2 * solanum lycopersicum 100000.0 1 PMID:4847569 -2.6.1.2 * sus scrofa 80000.0 2 PMID:454616 -2.6.1.2 * taraxacum brevicorniculatum 46127.0 1 * -2.6.1.2 * triticum aestivum 65000.0 2 PMID:22863564 -2.6.1.2 * zea mays 95000.0 2 PMID:16669068;PMID:1898070;PMID:6816789 -2.6.1.21 * bacillus sp. (in: firmicutes) 32500.0 1 PMID:7626635 -2.6.1.21 * bacillus subtilis 53000.0 1 PMID:4953710 -2.6.1.21 * bradyrhizobium japonicum 60000.0 1 PMID:1158891 -2.6.1.21 * desulfohalobium retbaense 70000.0 1 * -2.6.1.21 * lathyrus oleraceus 65000.0 1 PMID:4710577 -2.6.1.21 * lysinibacillus sphaericus 60000.0 3 PMID:1158891;PMID:863877 -2.6.1.22 * rattus norvegicus 105000.0 1 PMID:10989446 -2.6.1.24 * rattus norvegicus 80000.0 1 PMID:4381052 -2.6.1.26 * oryctolagus cuniculus 95000.0 2 PMID:4686924 -2.6.1.27 * clostridium sporogenes 97000.0 1 PMID:5697992 -2.6.1.27 * malassezia furfur 52500.0 2 PMID:24118363 -2.6.1.27 * rattus norvegicus 55000.0 1 PMID:12170594 -2.6.1.27 * zea mays 80000.0 3 * -2.6.1.28 * pseudomonas sp. 110000.0 2 * -2.6.1.3 * rattus norvegicus 84000.0 3 PMID:20209;PMID:7113743 -2.6.1.30 * mesorhizobium loti 154000.0 7 PMID:16545075 -2.6.1.30 * nicotiana tabacum 32000.0 1 * -2.6.1.33 * escherichia coli 180000.0 4 PMID:15271350 -2.6.1.36 * [flavobacterium] lutescens 116000.0 6 PMID:10965037;PMID:4088080;PMID:5722276;PMID:6771255 -2.6.1.36 * actinomyces sp. 48810.0 1 PMID:19374992 -2.6.1.36 * cyberlindnera jadinii 83000.0 2 PMID:1527704 -2.6.1.36 * mycobacterium tuberculosis 50000.0 2 PMID:16754985;PMID:16950391 -2.6.1.36 * streptomyces clavuligerus 51300.0 5 PMID:17288446;PMID:9172431 -2.6.1.37 * pseudomonas aeruginosa 65000.0 3 PMID:12107130;PMID:6406228 -2.6.1.37 * salmonella enterica 100000.0 2 PMID:12107130 -2.6.1.38 * comamonas testosteroni 70000.0 1 PMID:241324 -2.6.1.38 * streptomyces tendae 110000.0 3 * -2.6.1.39 * bos taurus 41000.0 1 PMID:2803240 -2.6.1.39 * candida albicans 73500.0 4 PMID:26619256 -2.6.1.39 * homo sapiens 104000.0 4 PMID:12126930;PMID:8087205 -2.6.1.39 * rattus norvegicus 100000.0 11 PMID:1857685;PMID:2803240;PMID:3003514;PMID:6830814;PMID:7493966;PMID:873907 -2.6.1.39 * saccharomyces cerevisiae 140000.0 3 PMID:21982920;PMID:5792664 -2.6.1.39 * thermus thermophilus 44000.0 2 PMID:15256574 -2.6.1.4 * homo sapiens 57000.0 1 PMID:19545238 -2.6.1.4 * hydrogenobacter thermophilus 62000.0 2 PMID:20214682 -2.6.1.4 * lactiplantibacillus plantarum 37000.0 1 PMID:5859 -2.6.1.4 * oryza sativa japonica group 240000.0 2 * -2.6.1.4 * rhodopseudomonas palustris 45500.0 2 PMID:12784618 -2.6.1.4 * zea mays 50000.0 1 PMID:10547044 -2.6.1.40 * rattus norvegicus 220000.0 4 PMID:10989446;PMID:2158891;PMID:2306461;PMID:8427875 -2.6.1.42 * arabidopsis thaliana 51900.0 1 PMID:17056707 -2.6.1.42 * brevibacillus brevis 93000.0 2 PMID:7542327 -2.6.1.42 * candida maltosa 93000.0 1 * -2.6.1.42 * canis lupus familiaris 96000.0 4 PMID:2853816 -2.6.1.42 * deinococcus radiodurans 41000.0 4 PMID:17554170 -2.6.1.42 * entodinium sp. 34000.0 1 PMID:239229 -2.6.1.42 * escherichia coli 197000.0 11 PMID:10989422;PMID:11412098;PMID:22031029;PMID:24206068;PMID:3069843;PMID:378964;PMID:782566 -2.6.1.42 * gluconobacter oxydans 82000.0 2 * -2.6.1.42 * haliangium ochraceum 70000.0 1 PMID:30902765 -2.6.1.42 * helicobacter pylori 68500.0 4 PMID:17077963 -2.6.1.42 * homo sapiens 90000.0 4 PMID:12504794;PMID:2853816 -2.6.1.42 * hordeum vulgare 95000.0 2 PMID:16932885 -2.6.1.42 * lacticaseibacillus paracasei 50000.0 2 PMID:14962140;PMID:2156837 -2.6.1.42 * lactococcus lactis 64000.0 2 PMID:10653720 -2.6.1.42 * methanococcus aeolicus 188000.0 2 PMID:1729242;PMID:2002010 -2.6.1.42 * mycobacterium tuberculosis 80000.0 3 PMID:19923721 -2.6.1.42 * neurospora crassa 88000.0 2 PMID:4268214 -2.6.1.42 * nicotiana benthamiana 45280.0 1 PMID:19568767 -2.6.1.42 * ovis aries 43070.0 3 PMID:11072075;PMID:9914481 -2.6.1.42 * rattus norvegicus 91000.0 12 PMID:11733007;PMID:14962140;PMID:16194549;PMID:2156837;PMID:2853816;PMID:8381418 -2.6.1.42 * salmonella enterica subsp. enterica serovar typhimurium 204900.0 4 PMID:2669973;PMID:378964 -2.6.1.42 * schizosaccharomyces pombe 42500.0 1 PMID:9483807 -2.6.1.42 * streptococcus mutans 38140.0 1 PMID:22868765 -2.6.1.42 * sus scrofa 75000.0 3 PMID:3241563;PMID:3980626;PMID:4979711;PMID:5922965 -2.6.1.42 * thermoproteus uzoniensis 60000.0 2 PMID:26872794 -2.6.1.42 * vulcanisaeta moutnovskia 145000.0 1 PMID:27871372 -2.6.1.43 * bos taurus 245000.0 4 PMID:7287716;PMID:7364767 -2.6.1.43 * candida albicans 60260.0 3 PMID:2154954 -2.6.1.43 * cenchrus americanus 168000.0 2 * -2.6.1.43 * chlorella regularis 126000.0 2 PMID:6486814 -2.6.1.43 * clostridium tetanomorphum 111000.0 5 PMID:7061418 -2.6.1.43 * devosia riboflavina 190000.0 2 PMID:3170516 -2.6.1.43 * gallus gallus 63000.0 1 PMID:2676644 -2.6.1.43 * mus musculus 146000.0 1 PMID:2338161 -2.6.1.43 * raphanus sativus 123000.0 1 * -2.6.1.43 * rattus norvegicus 260000.0 10 PMID:2050138;PMID:3740843;PMID:3970940;PMID:7858420 -2.6.1.43 * saccharomyces cerevisiae 59000.0 1 PMID:2154954 -2.6.1.44 * anabaena sp. 41736.0 1 PMID:15657930 -2.6.1.44 * arabidopsis thaliana 92140.0 5 PMID:10739960;PMID:11309139;PMID:12529529;PMID:8922378 -2.6.1.44 * canis lupus familiaris 175000.0 4 PMID:3933486;PMID:629740 -2.6.1.44 * columba livia 200000.0 4 PMID:1654790 -2.6.1.44 * felis catus 80000.0 3 PMID:3933486;PMID:629740 -2.6.1.44 * gallus gallus 200000.0 3 PMID:1654790 -2.6.1.44 * homo sapiens 90000.0 8 PMID:10960483;PMID:11309139;PMID:11717523;PMID:12686111;PMID:15849465;PMID:16971151;PMID:18448374;PMID:20018850;PMID:20133649;PMID:8051936;PMID:8922378 -2.6.1.44 * hydrogenobacter thermophilus 69000.0 1 PMID:20214682 -2.6.1.44 * medicago truncatula 53000.0 1 PMID:16899523 -2.6.1.44 * mus musculus 80000.0 3 PMID:3933486;PMID:629740 -2.6.1.44 * rattus norvegicus 236000.0 13 PMID:10739960;PMID:11309139;PMID:2503051;PMID:3933486;PMID:629740;PMID:6803844;PMID:8797099 -2.6.1.44 * saccharomyces cerevisiae 80000.0 2 PMID:3933486;PMID:629740 -2.6.1.44 * scomberomorus sp. 200000.0 1 PMID:6697688 -2.6.1.44 * suncus murinus 210000.0 1 PMID:2907870 -2.6.1.44 * thermococcus litoralis 170000.0 3 PMID:15292154 -2.6.1.45 * arabidopsis thaliana 82400.0 2 PMID:18235971 -2.6.1.45 * chlamydomonas reinhardtii 47700.0 1 * -2.6.1.45 * cucumis sativus 170000.0 3 PMID:16664409 -2.6.1.45 * hyphomicrobium methylovorum 150000.0 5 PMID:19264108;PMID:2114288;PMID:8898880 -2.6.1.45 * lathyrus oleraceus 105000.0 1 PMID:6407397 -2.6.1.45 * methylococcus capsulatus 120000.0 1 PMID:30511326 -2.6.1.45 * methylosinus trichosporium 170000.0 1 PMID:30511326 -2.6.1.45 * methylotuvimicrobium alcaliphilum 80000.0 1 PMID:30511326 -2.6.1.45 * oryza sativa japonica group 350000.0 2 * -2.6.1.45 * secale cereale 91200.0 2 PMID:2127336 -2.6.1.45 * triticum aestivum 88000.0 2 PMID:15940352 -2.6.1.45 * zea mays 105000.0 3 PMID:15940352 -2.6.1.46 * halomonas elongata 44000.0 1 PMID:9864317 -2.6.1.46 * pseudomonas aeruginosa 183000.0 2 PMID:15317763 -2.6.1.48 * meyerozyma guilliermondii 118000.0 2 PMID:3778871 -2.6.1.48 * pseudomonas aeruginosa 46290.0 3 PMID:17388807 -2.6.1.5 * agama agama 130000.0 1 PMID:2886155 -2.6.1.5 * anchusa officinalis 220000.0 4 PMID:2889425 -2.6.1.5 * crithidia fasciculata 100000.0 3 PMID:2890101 -2.6.1.5 * entodinium caudatum 65000.0 1 * -2.6.1.5 * leishmania donovani 98600.0 1 PMID:31393078 -2.6.1.5 * leishmania major 49600.0 1 PMID:19443056 -2.6.1.5 * papaver somniferum 46000.0 1 PMID:21949209 -2.6.1.5 * rana temporaria 85000.0 1 PMID:18134 -2.6.1.5 * rattus norvegicus 160000.0 16 PMID:14026;PMID:15865;PMID:1682148;PMID:25067;PMID:40452;PMID:4145779;PMID:4396841;PMID:6114952 -2.6.1.5 * staphylococcus aureus 50000.0 2 PMID:17565195 -2.6.1.5 * trichoderma viride 110000.0 1 * -2.6.1.5 * trypanosoma cruzi 91000.0 3 PMID:17678649;PMID:8100416 -2.6.1.5 * variovorax paradoxus 46420.0 1 PMID:23087034 -2.6.1.50 * micromonospora echinospora 76000.0 1 PMID:2729940 -2.6.1.50 * streptomyces fradiae 46951.0 2 PMID:15827636 -2.6.1.50 * streptomyces griseus 100000.0 3 PMID:9238101 -2.6.1.51 * canis lupus familiaris 80000.0 2 PMID:851432 -2.6.1.51 * felis catus 80000.0 2 PMID:851432 -2.6.1.51 * mus musculus 80000.0 2 PMID:851432 -2.6.1.51 * rattus norvegicus 80000.0 9 PMID:12376828;PMID:12742;PMID:2691502;PMID:851432;PMID:8797099;PMID:8920916 -2.6.1.52 * acanthamoeba castellanii 47000.0 2 PMID:25622549 -2.6.1.52 * antheraea pernyi 40090.0 1 * -2.6.1.52 * arabidopsis thaliana 80000.0 2 PMID:30034403;PMID:9881164 -2.6.1.52 * bos taurus 90700.0 5 PMID:10637769;PMID:3579302 -2.6.1.52 * entamoeba histolytica 155000.0 1 PMID:22386871 -2.6.1.52 * escherichia coli 81200.0 4 PMID:8706854 -2.6.1.52 * glycine max 85000.0 1 * -2.6.1.52 * homo sapiens 40000.0 2 PMID:12633500 -2.6.1.52 * methanothermobacter thermautotrophicus 41680.0 1 PMID:8206881 -2.6.1.52 * niallia circulans 70000.0 4 PMID:8695645 -2.6.1.52 * ovis aries 96000.0 2 PMID:6022873 -2.6.1.52 * synechocystis sp. 84000.0 2 PMID:25701735 -2.6.1.52 * tetradesmus obliquus 80000.0 3 * -2.6.1.55 * achromobacter superficialis 156000.0 1 PMID:3003495;PMID:5012173 -2.6.1.55 * bifidobacterium catenulatum subsp. kashiwanohense 109700.0 1 PMID:31088892 -2.6.1.57 * [brevibacterium] flavum 260000.0 2 PMID:500563 -2.6.1.57 * aspergillus fumigatus 107000.0 1 PMID:30547035 -2.6.1.57 * azospirillum brasilense 66000.0 4 PMID:15043864;PMID:8868238 -2.6.1.57 * bacillus subtilis 73000.0 3 PMID:11213;PMID:418816 -2.6.1.57 * brevibacillus brevis 71000.0 2 PMID:2440856 -2.6.1.57 * brevibacterium linens 126000.0 1 * -2.6.1.57 * candida albicans 97000.0 7 PMID:26619256 -2.6.1.57 * candida maltosa 105000.0 3 * -2.6.1.57 * corynebacterium ammoniagenes 260000.0 1 PMID:500563 -2.6.1.57 * corynebacterium glutamicum 260000.0 2 PMID:500563 -2.6.1.57 * escherichia coli 90000.0 6 PMID:3298975;PMID:352693;PMID:3907634;PMID:7007315;PMID:8218300;PMID:9058208 -2.6.1.57 * flavobacterium sp. 120000.0 1 PMID:6816714 -2.6.1.57 * klebsiella aerogenes 90000.0 2 PMID:352693;PMID:7007315 -2.6.1.57 * lactococcus lactis 170000.0 4 * -2.6.1.57 * methanococcus aeolicus 150000.0 2 PMID:1729242 -2.6.1.57 * paracoccus denitrificans 83000.0 3 PMID:8218300;PMID:9058208 -2.6.1.57 * pseudomonas aeruginosa 64000.0 2 PMID:6128337 -2.6.1.57 * pseudomonas putida 44200.0 2 * -2.6.1.57 * pyrococcus furiosus 92000.0 2 PMID:7873596;PMID:8125113 -2.6.1.57 * pyrococcus horikoshii 56000.0 2 PMID:10671523 -2.6.1.57 * rattus norvegicus 100000.0 2 PMID:3600371 -2.6.1.57 * rhizobium leguminosarum 53000.0 1 PMID:1520732 -2.6.1.57 * rosa hybrid cultivar 46300.0 1 PMID:22236980 -2.6.1.57 * stutzerimonas stutzeri 86000.0 3 PMID:15043864 -2.6.1.57 * thermococcus litoralis 110000.0 4 PMID:8125113 -2.6.1.57 * vigna radiata 59000.0 1 * -2.6.1.58 * mus musculus 85000.0 2 PMID:14070 -2.6.1.59 * escherichia coli 180000.0 2 PMID:15271350 -2.6.1.6 * glycine max 93300.0 2 * -2.6.1.6 * rattus norvegicus 65000.0 1 PMID:974100 -2.6.1.60 * macaca fuscata 80000.0 2 PMID:25837;PMID:3037260 -2.6.1.60 * rattus norvegicus 80000.0 3 PMID:25837;PMID:3037260 -2.6.1.62 * arabidopsis thaliana 90000.0 1 PMID:22547782 -2.6.1.62 * corynebacterium glutamicum 24000.0 1 * -2.6.1.62 * escherichia coli 94000.0 2 PMID:1092681;PMID:374976 -2.6.1.62 * mycobacterium tuberculosis 189000.0 2 PMID:16984394 -2.6.1.63 * macaca fuscata 80000.0 2 PMID:25837 -2.6.1.63 * rattus norvegicus 80000.0 2 PMID:25837 -2.6.1.64 * bos taurus 97000.0 2 PMID:3709533 -2.6.1.64 * rattus norvegicus 330000.0 11 PMID:10900257;PMID:241631;PMID:4822504;PMID:727444;PMID:7476916;PMID:8914928;PMID:9765069 -2.6.1.64 * thermus thermophilus 82000.0 3 PMID:14769873 -2.6.1.67 * candida guilliermondii var. membranaefaciens 100000.0 2 PMID:3622507 -2.6.1.7 * aedes aegypti 97000.0 4 PMID:12110301 -2.6.1.7 * haemaphysalis longicornis 46480.0 3 PMID:19381689 -2.6.1.7 * hansenula schneggii 106000.0 4 PMID:3003516;PMID:3086302 -2.6.1.7 * homo sapiens 51000.0 3 PMID:15606768;PMID:25231977 -2.6.1.7 * pyrococcus horikoshii 100000.0 3 PMID:16511030;PMID:22792273 -2.6.1.7 * rattus norvegicus 100000.0 11 PMID:1218085;PMID:3003514;PMID:3037259;PMID:6830814;PMID:7493966;PMID:7891071 -2.6.1.70 * pseudomonas putida 72000.0 2 * -2.6.1.71 * meyerozyma guilliermondii 90000.0 1 * -2.6.1.73 * brassica carinata 290000.0 2 PMID:16667931 -2.6.1.73 * brassica napus 290000.0 2 PMID:16667931 -2.6.1.74 * bacillus licheniformis 30000.0 1 PMID:3228235 -2.6.1.75 * rattus norvegicus 64000.0 2 PMID:2852419 -2.6.1.76 * acinetobacter baumannii 188000.0 3 PMID:9260954 -2.6.1.76 * haemophilus influenzae 56200.0 2 PMID:9514614 -2.6.1.76 * halomonas elongata 260000.0 2 PMID:9864317 -2.6.1.76 * paenibacillus lautus 200000.0 1 PMID:31921013 -2.6.1.77 * bilophila wadsworthia 197000.0 3 PMID:11082195;PMID:12471498 -2.6.1.77 * castellaniella defragrans 51000.0 1 PMID:12471498 -2.6.1.77 * geobacillus thermodenitrificans subsp. thermodenitrificans 45000.0 1 PMID:26577674 -2.6.1.77 * paracoccus denitrificans 50000.0 1 PMID:15184572;PMID:23603744 -2.6.1.77 * pseudomonas aeruginosa 51000.0 1 PMID:12471498 -2.6.1.77 * rhodococcus opacus 50000.0 1 PMID:15184572;PMID:23603744 -2.6.1.78 * anchusa officinalis 220000.0 3 PMID:3196038 -2.6.1.78 * arabidopsis thaliana 43000.0 1 PMID:20883697 -2.6.1.79 * arabidopsis thaliana 43000.0 1 PMID:20883697 -2.6.1.79 * nicotiana sylvestris 88000.0 1 PMID:3298985 -2.6.1.80 * hordeum vulgare 90000.0 4 PMID:10557244 -2.6.1.82 * escherichia coli 100000.0 3 PMID:12617754;PMID:22949197 -2.6.1.83 * arabidopsis thaliana 51000.0 1 PMID:16361515 -2.6.1.83 * chlamydomonas reinhardtii 100200.0 2 PMID:21633707 -2.6.1.83 * methanococcus maripaludis 47900.0 1 PMID:20418392 -2.6.1.84 * pseudomonas aeruginosa 79300.0 4 PMID:17416668 -2.6.1.85 * agaricus bisporus 80600.0 1 PMID:25152061 -2.6.1.85 * escherichia coli 20000.0 1 PMID:8679677 -2.6.1.85 * pseudomonas aeruginosa 71251.0 1 PMID:23099261 -2.6.1.85 * stenotrophomonas maltophilia 49500.0 1 PMID:23230967 -2.6.1.86 * burkholderia lata 70000.0 1 PMID:21454481 -2.6.1.86 * pseudomonas aeruginosa 71251.0 1 PMID:23099261 -2.6.1.86 * streptomyces globisporus 58500.0 1 PMID:18182490 -2.6.1.88 * escherichia coli 45647.0 1 PMID:15280032 -2.6.1.88 * klebsiella pneumoniae 90000.0 2 PMID:10074065 -2.6.1.9 * bacillus subtilis 33000.0 1 PMID:11213 -2.6.1.9 * escherichia coli 60000.0 1 PMID:11518529 -2.6.1.9 * nicotiana tabacum 53000.0 2 PMID:11289510 -2.6.1.9 * salmonella enterica subsp. enterica serovar typhimurium 74000.0 4 PMID:4632247;PMID:5337155 -2.6.1.9 * zymomonas mobilis 85000.0 2 PMID:7883715 -2.6.1.90 * streptomyces ravidus 41710.0 1 PMID:21264378 -2.6.1.93 * niallia circulans 52070.0 2 PMID:17206729 -2.6.1.93 * streptomyces fradiae 48060.0 2 PMID:17206729 -2.6.1.95 * streptomyces fradiae 48060.0 2 PMID:17206729 -2.6.1.96 * arabidopsis thaliana 57500.0 3 PMID:19264755 -2.6.1.96 * brassica napus 55000.0 3 * -2.6.1.96 * nicotiana tabacum 55000.0 1 * -2.6.99.1 * homo sapiens 120000.0 1 PMID:218192 -2.6.99.3 * streptomyces lavendulae 126000.0 2 PMID:23529730 -2.7.1.1 * aeropyrum pernix 36000.0 2 PMID:12374829 -2.7.1.1 * arabidopsis thaliana 51000.0 1 PMID:20650273 -2.7.1.1 * ascaris suum 100000.0 1 * -2.7.1.1 * aspergillus niger 100000.0 2 PMID:2802617;PMID:3960030;PMID:6639059;PMID:8031843 -2.7.1.1 * bos taurus 111000.0 2 PMID:15724432 -2.7.1.1 * brassica rapa subsp. oleifera 47000.0 1 * -2.7.1.1 * brugia malayi 72000.0 1 PMID:18499511 -2.7.1.1 * bubalus bubalis 200000.0 2 PMID:12615324;PMID:9440232 -2.7.1.1 * candida maltosa 110000.0 3 * -2.7.1.1 * canis lupus familiaris 50000.0 1 PMID:15251466;PMID:6489338 -2.7.1.1 * drosophila melanogaster 50000.0 8 PMID:6768723 -2.7.1.1 * eimeria tenella 50500.0 2 PMID:27150971 -2.7.1.1 * helianthus annuus 52600.0 1 PMID:20889232 -2.7.1.1 * homo sapiens 118000.0 12 PMID:10800927;PMID:18397317;PMID:19187021;PMID:2043117;PMID:3341751;PMID:3756183;PMID:7061426;PMID:7114848;PMID:8690154;PMID:8717435;PMID:9493266 -2.7.1.1 * kluyveromyces lactis 54000.0 4 PMID:12882981 -2.7.1.1 * lithobates sylvaticus 100000.0 1 PMID:21616160 -2.7.1.1 * lysinibacillus sphaericus 33000.0 1 PMID:17400775 -2.7.1.1 * macrobrachium nipponense 49720.0 1 PMID:28608798 -2.7.1.1 * mammalia 100000.0 1 PMID:12756287 -2.7.1.1 * mus musculus 116000.0 3 PMID:7508920 -2.7.1.1 * nicotiana tabacum 54000.0 1 PMID:15670855 -2.7.1.1 * ogataea angusta 54200.0 2 PMID:12383517;PMID:14530868 -2.7.1.1 * oncorhynchus mykiss 52000.0 1 PMID:19336256;PMID:19807849 -2.7.1.1 * oryctolagus cuniculus 112000.0 7 PMID:6526642;PMID:7061426;PMID:7114848;PMID:7263629 -2.7.1.1 * rattus norvegicus 108000.0 12 PMID:10800927;PMID:11812227;PMID:11883910;PMID:19187021;PMID:19336256;PMID:19807849;PMID:2802617;PMID:3338084;PMID:3593283;PMID:3960030;PMID:6639059;PMID:8031843;PMID:8690154 -2.7.1.1 * saccharomyces cerevisiae 60000.0 3 PMID:1783664;PMID:21075772 -2.7.1.1 * schistosoma mansoni 55000.0 2 PMID:8936600 -2.7.1.1 * schizosaccharomyces pombe 88000.0 4 PMID:8549830;PMID:9666312 -2.7.1.1 * schwanniomyces occidentalis 53400.0 1 PMID:7614556 -2.7.1.1 * solanum tuberosum 66000.0 2 * -2.7.1.1 * sulfurisphaera tokodaii 64000.0 3 PMID:16484213 -2.7.1.1 * sus scrofa 100000.0 2 PMID:2802617;PMID:3960030;PMID:6639059;PMID:8031843 -2.7.1.1 * thermoproteus tenax 40000.0 3 PMID:12626506 -2.7.1.1 * thermus caldophilus 120000.0 3 PMID:16053915 -2.7.1.1 * toxoplasma gondii 51465.0 2 PMID:12076625 -2.7.1.1 * trypanosoma brucei 50000.0 1 PMID:15251466;PMID:6489338 -2.7.1.1 * trypanosoma cruzi 200000.0 7 PMID:12615324;PMID:9440232 -2.7.1.1 * vitis vinifera 51000.0 1 PMID:24213599 -2.7.1.1 * xenopus laevis 100000.0 1 PMID:26797504 -2.7.1.100 * klebsiella pneumoniae 50000.0 2 PMID:8694776 -2.7.1.100 * lupinus luteus 70000.0 1 PMID:16662931 -2.7.1.100 * oryza sativa 50000.0 2 PMID:15557090 -2.7.1.101 * mycobacterium butyricum 63000.0 1 PMID:6269638 -2.7.1.102 * kluyvera cryocrescens 21000.0 1 PMID:6249593 -2.7.1.105 * arabidopsis thaliana 370000.0 2 PMID:11672433 -2.7.1.105 * bos taurus 225000.0 8 PMID:10521487;PMID:1325453;PMID:2837472;PMID:2986553;PMID:2998341 -2.7.1.105 * columba sp. 110000.0 2 PMID:2986553;PMID:3019688 -2.7.1.105 * escherichia coli 66000.0 2 PMID:18762190;PMID:19465020 -2.7.1.105 * gallus gallus 110000.0 2 PMID:2986553;PMID:3019688;PMID:8109976 -2.7.1.105 * helianthus tuberosus 90000.0 1 PMID:3023092 -2.7.1.105 * homo sapiens 120000.0 4 PMID:24280138;PMID:2961616;PMID:2998341;PMID:9276680 -2.7.1.105 * mytilus galloprovincialis 100000.0 2 * -2.7.1.105 * pelophylax lessonae 55800.0 2 PMID:8391552 -2.7.1.105 * rattus norvegicus 112500.0 13 PMID:2542332;PMID:2826464;PMID:2837472;PMID:2986553;PMID:2998341;PMID:3000438;PMID:3014526;PMID:3019688;PMID:6288034;PMID:6458290;PMID:8385136;PMID:8805587;PMID:9276680 -2.7.1.105 * ricinus communis 90000.0 1 PMID:3023092 -2.7.1.105 * saccharomyces cerevisiae 600000.0 3 PMID:2831055;PMID:2961616;PMID:9276680 -2.7.1.105 * sparus aurata 98000.0 2 PMID:3019688;PMID:8109976 -2.7.1.105 * spinacia oleracea 390000.0 5 PMID:11856361;PMID:3023092 -2.7.1.105 * trypanosoma brucei 140000.0 7 PMID:16008555 -2.7.1.107 * arabidopsis thaliana 140000.0 2 PMID:14665624 -2.7.1.107 * bacillus subtilis 34000.0 1 PMID:17535816 -2.7.1.107 * catharanthus roseus 250000.0 3 PMID:16666963 -2.7.1.107 * escherichia coli 15400.0 5 PMID:218816;PMID:2828054;PMID:2984194 -2.7.1.107 * gallus gallus 75000.0 1 PMID:185051 -2.7.1.107 * homo sapiens 152000.0 15 PMID:12799190;PMID:12810723;PMID:2172248;PMID:2175712;PMID:31893253;PMID:8626588;PMID:9438377 -2.7.1.107 * mesocricetus auratus 126800.0 1 PMID:9438377 -2.7.1.107 * mus musculus 104000.0 3 PMID:19263516;PMID:19364481 -2.7.1.107 * rattus norvegicus 110000.0 7 PMID:12799190;PMID:19087171;PMID:19691842;PMID:2176468;PMID:9438377 -2.7.1.107 * spodoptera littoralis 109500.0 1 PMID:18839449 -2.7.1.107 * staphylococcus aureus 42000.0 2 PMID:18611377 -2.7.1.107 * sus scrofa 82600.0 4 PMID:19264149;PMID:6296111;PMID:9438377 -2.7.1.108 * homo sapiens 60000.0 2 PMID:12213788 -2.7.1.11 * aeropyrum pernix 115000.0 3 PMID:11506912;PMID:11797046 -2.7.1.11 * amycolatopsis methanolica 110000.0 3 PMID:11717283 -2.7.1.11 * anguilla anguilla 340000.0 1 * -2.7.1.11 * arabidopsis thaliana 58600.0 7 PMID:17485088 -2.7.1.11 * ascaris suum 400000.0 3 PMID:6218373;PMID:6460770 -2.7.1.11 * aspergillus niger 85000.0 1 PMID:19379783 -2.7.1.11 * bacillus licheniformis 135000.0 1 PMID:6218376 -2.7.1.11 * bacillus sp. (in: firmicutes) 135000.0 1 * -2.7.1.11 * bombus atratus 360000.0 1 PMID:2972719 -2.7.1.11 * bos taurus 400000.0 4 PMID:1386580 -2.7.1.11 * camelus dromedarius 90000.0 1 PMID:2957144 -2.7.1.11 * canis lupus familiaris 86000.0 3 PMID:30918224 -2.7.1.11 * clostridium pasteurianum 144000.0 3 PMID:6218378 -2.7.1.11 * crassostrea virginica 340000.0 1 PMID:6218372 -2.7.1.11 * cucumis sativus 180000.0 7 * -2.7.1.11 * cyprinus carpio 340000.0 1 * -2.7.1.11 * desulfurococcus amylolyticus 140000.0 2 PMID:10795681;PMID:11976749 -2.7.1.11 * dictyostelium discoideum 92400.0 1 PMID:10328829 -2.7.1.11 * dunaliella marina 644000.0 3 PMID:6462110 -2.7.1.11 * escherichia coli 142000.0 5 PMID:6218375 -2.7.1.11 * gadus morhua 335000.0 1 * -2.7.1.11 * haloferax volcanii 194000.0 3 PMID:25287957 -2.7.1.11 * homo sapiens 79500.0 3 PMID:7488210 -2.7.1.11 * jaculus orientalis 320000.0 2 PMID:1386797 -2.7.1.11 * klebsiella aerogenes 90000.0 1 PMID:4242639 -2.7.1.11 * kluyveromyces lactis 845000.0 3 PMID:9392075 -2.7.1.11 * komagataella pastoris 975000.0 4 PMID:12125050 -2.7.1.11 * lactococcus lactis 144500.0 1 PMID:6218377 -2.7.1.11 * lymantria dispar 330000.0 2 * -2.7.1.11 * monoraphidium minutum 6000000.0 3 PMID:16667595 -2.7.1.11 * mus musculus 300000.0 6 PMID:17229148;PMID:19889946;PMID:6218371;PMID:9199509 -2.7.1.11 * musa acuminata 210000.0 2 PMID:12721855 -2.7.1.11 * oncorhynchus mykiss 478000.0 3 PMID:1477103 -2.7.1.11 * oryctolagus cuniculus 500000.0 5 PMID:6460770 -2.7.1.11 * rattus norvegicus 413000.0 3 PMID:6223631 -2.7.1.11 * ricinus communis 220000.0 3 PMID:16667239;PMID:6448583 -2.7.1.11 * saccharomyces cerevisiae 835000.0 5 PMID:6218374;PMID:6455071 -2.7.1.11 * schizosaccharomyces pombe 790000.0 2 PMID:11015725 -2.7.1.11 * solanum lycopersicum 180000.0 2 * -2.7.1.11 * solanum tuberosum 800000.0 8 PMID:2975159 -2.7.1.11 * sparus aurata 662000.0 4 PMID:17229526;PMID:18483063 -2.7.1.11 * spinacia oleracea 200000.0 6 PMID:17229148;PMID:19889946 -2.7.1.11 * sporolactobacillus inulinus 135000.0 3 PMID:28190098 -2.7.1.11 * sus scrofa 3500000.0 1 PMID:124390 -2.7.1.11 * tetrahymena pyriformis 300000.0 1 PMID:6452171 -2.7.1.11 * thermococcus kodakarensis 52000.0 1 PMID:31337538 -2.7.1.11 * thermotoga maritima 200000.0 4 PMID:10795681;PMID:11133978;PMID:11976749 -2.7.1.11 * triticum aestivum 182000.0 1 * -2.7.1.11 * trypanosoma brucei 220000.0 5 PMID:12595717;PMID:3158309 -2.7.1.113 * bacillus subtilis 49000.0 4 PMID:11078735 -2.7.1.113 * bos taurus 56000.0 2 PMID:2845866 -2.7.1.113 * dictyostelium discoideum 30000.0 1 PMID:17448496 -2.7.1.113 * homo sapiens 58000.0 3 PMID:12363036;PMID:6295492 -2.7.1.113 * lactobacillus acidophilus 27200.0 1 PMID:8172906 -2.7.1.113 * mus musculus 44000.0 1 PMID:6260206 -2.7.1.113 * sus scrofa 58500.0 1 PMID:231969 -2.7.1.114 * herpes simplex virus 111000.0 1 PMID:6267178 -2.7.1.118 * herpes simplex virus 75200.0 1 PMID:6267178 -2.7.1.119 * streptomyces hygroscopicus 42000.0 3 PMID:24200799;PMID:2995542;PMID:3026811 -2.7.1.12 * corynebacterium glutamicum 18000.0 1 PMID:19399347 -2.7.1.12 * escherichia coli 100000.0 4 PMID:8925917 -2.7.1.12 * homo sapiens 85000.0 3 PMID:24896608 -2.7.1.12 * zymomonas mobilis 18000.0 1 PMID:2990475 -2.7.1.127 * bos taurus 52000.0 5 PMID:2549973;PMID:8948463 -2.7.1.127 * gallus gallus 36250.0 1 * -2.7.1.127 * homo sapiens 88000.0 8 PMID:10329669;PMID:15740635;PMID:26446452;PMID:8390223;PMID:9155020 -2.7.1.127 * mus musculus 125000.0 6 PMID:15381088;PMID:26446452;PMID:27036498 -2.7.1.127 * rattus norvegicus 160000.0 17 PMID:10329669;PMID:12649294;PMID:15740635;PMID:16123124;PMID:1693074;PMID:2160980;PMID:26446452;PMID:2836386;PMID:7738477;PMID:9155020;PMID:9374536 -2.7.1.127 * sus scrofa 93000.0 2 PMID:2839156 -2.7.1.13 * pseudomonas aeruginosa 32600.0 1 PMID:10931350 -2.7.1.134 * homo sapiens 47000.0 2 PMID:8662638 -2.7.1.134 * rattus norvegicus 46000.0 2 PMID:2829850;PMID:8999935 -2.7.1.136 * escherichia coli 34000.0 1 PMID:2478074 -2.7.1.137 * bos taurus 190000.0 13 PMID:12672472;PMID:1322797;PMID:1850737;PMID:2167854;PMID:2174051;PMID:7683666;PMID:7713498;PMID:8139567;PMID:9043658 -2.7.1.137 * candida albicans 118000.0 1 PMID:10870104 -2.7.1.137 * gallus gallus 110000.0 2 PMID:19117024 -2.7.1.137 * homo sapiens 128900.0 9 PMID:12535795;PMID:12672472;PMID:1322797;PMID:15135396;PMID:7713498;PMID:8139567;PMID:9043658 -2.7.1.137 * mammalia 110000.0 2 PMID:12672472 -2.7.1.137 * mus musculus 110000.0 3 PMID:12672472;PMID:1322797;PMID:7713498;PMID:8139567;PMID:9043658 -2.7.1.137 * rattus norvegicus 190000.0 3 PMID:2174051;PMID:7683666 -2.7.1.137 * saccharomyces cerevisiae 95000.0 1 PMID:2247081 -2.7.1.138 * homo sapiens 62000.0 2 PMID:16269826;PMID:17274985;PMID:17392267 -2.7.1.138 * mus musculus 62000.0 1 PMID:17274985;PMID:17392267 -2.7.1.144 * staphylococcus aureus 82000.0 2 PMID:6251066 -2.7.1.144 * streptococcus mutans 34000.0 1 PMID:1328153 -2.7.1.145 * bombyx mori 69300.0 3 PMID:11812127 -2.7.1.145 * drosophila melanogaster 57700.0 12 PMID:10446143;PMID:10692477;PMID:11812127;PMID:9461577;PMID:9598112 -2.7.1.145 * xenopus laevis 49800.0 3 PMID:11812127 -2.7.1.146 * archaeoglobus fulgidus 200000.0 4 PMID:15064987 -2.7.1.146 * methanocaldococcus jannaschii 55000.0 5 PMID:11717273;PMID:11856730 -2.7.1.146 * pyrococcus furiosus 180000.0 2 PMID:10409652;PMID:11265478 -2.7.1.146 * thermococcus kodakarensis 52000.0 1 PMID:31337538 -2.7.1.146 * thermococcus litoralis 125000.0 2 PMID:12832801 -2.7.1.146 * thermococcus zilligii 200000.0 5 PMID:10356998;PMID:11342216 -2.7.1.147 * archaeoglobus fulgidus 50000.0 1 PMID:12802482 -2.7.1.147 * methanocaldococcus jannaschii 55000.0 2 PMID:11856730 -2.7.1.147 * mus musculus 60300.0 2 PMID:14975750 -2.7.1.147 * pyrococcus furiosus 100000.0 4 PMID:11098152;PMID:11265478;PMID:11978175;PMID:8530474 -2.7.1.147 * thermococcus litoralis 54000.0 2 PMID:11098152 -2.7.1.148 * aquifex aeolicus 30000.0 1 PMID:18422643 -2.7.1.148 * escherichia coli 62000.0 1 PMID:19198899 -2.7.1.148 * ginkgo biloba 39900.0 2 PMID:18668260 -2.7.1.148 * solanum lycopersicum 36400.0 1 PMID:10880567 -2.7.1.148 * tripterygium wilfordii 42850.0 1 PMID:27071250 -2.7.1.149 * danio rerio 46000.0 1 PMID:23542014 -2.7.1.149 * gallus gallus 95000.0 2 PMID:17303380;PMID:27208178 -2.7.1.149 * homo sapiens 97000.0 7 PMID:17303380;PMID:18753295;PMID:20583997;PMID:23758345 -2.7.1.149 * mus musculus 47000.0 1 PMID:18753295 -2.7.1.15 * corynebacterium glutamicum 30800.0 1 PMID:18375800 -2.7.1.15 * escherichia coli 62000.0 1 PMID:9385653 -2.7.1.15 * leishmania donovani 38000.0 1 PMID:29400319 -2.7.1.15 * salmonella enterica 33230.0 1 PMID:10648508 -2.7.1.15 * salmonella enterica subsp. enterica serovar typhimurium 67800.0 2 PMID:4376665 -2.7.1.150 * homo sapiens 237000.0 1 PMID:16448788 -2.7.1.150 * saccharomyces cerevisiae 257000.0 1 PMID:12413484 -2.7.1.151 * arabidopsis thaliana 33000.0 1 PMID:18165921 -2.7.1.151 * homo sapiens 47219.0 1 PMID:12027805 -2.7.1.151 * oryza sativa 234000.0 2 * -2.7.1.151 * rattus norvegicus 44400.0 2 PMID:11226235;PMID:16123124 -2.7.1.153 * homo sapiens 120000.0 12 PMID:25908763;PMID:7624799;PMID:9113989;PMID:9235916 -2.7.1.153 * mus musculus 110000.0 4 PMID:25908763 -2.7.1.153 * rattus norvegicus 110000.0 6 PMID:25908763 -2.7.1.154 * homo sapiens 190000.0 5 PMID:15654916;PMID:27644332;PMID:9830063 -2.7.1.154 * mus musculus 170000.0 3 PMID:15654916;PMID:8663140 -2.7.1.154 * rattus norvegicus 180000.0 2 PMID:11931646;PMID:9516481 -2.7.1.156 * salmonella enterica 20000.0 1 PMID:12195810 -2.7.1.156 * salmonella enterica subsp. enterica serovar typhimurium 49000.0 5 PMID:10529169;PMID:7559521;PMID:9601028 -2.7.1.157 * homo sapiens 57000.0 1 PMID:16203137 -2.7.1.157 * sus scrofa 50000.0 2 PMID:8702831;PMID:8798585 -2.7.1.158 * cryptococcus neoformans 41000.0 1 PMID:28919350 -2.7.1.158 * glycine max 52000.0 1 PMID:7961779 -2.7.1.158 * ricinus communis 63000.0 1 PMID:24463774 -2.7.1.158 * schizosaccharomyces pombe 143000.0 1 PMID:20624911 -2.7.1.158 * zea mays 48850.0 1 PMID:17535825 -2.7.1.159 * arabidopsis thaliana 36200.0 1 PMID:9126335 -2.7.1.159 * bos taurus 48000.0 1 PMID:8662638 -2.7.1.159 * homo sapiens 60000.0 2 PMID:12324474;PMID:8662638 -2.7.1.159 * oryza sativa 38800.0 2 PMID:18421420;PMID:22038091 -2.7.1.159 * rattus norvegicus 36000.0 1 PMID:1331051 -2.7.1.16 * anoxybacillus kestanbolensis 61000.0 1 * -2.7.1.16 * escherichia coli 100000.0 1 PMID:5336963 -2.7.1.160 * homo sapiens 27800.0 1 PMID:14504659 -2.7.1.160 * saccharomyces cerevisiae 30000.0 3 PMID:11705403;PMID:15611301;PMID:9148937 -2.7.1.161 * methanocaldococcus jannaschii 19700.0 3 PMID:18245297 -2.7.1.162 * bifidobacterium longum 42500.0 1 PMID:24816108 -2.7.1.162 * bifidobacterium longum subsp. infantis 42500.0 1 PMID:24816108 -2.7.1.163 * escherichia coli 39100.0 4 PMID:15802221;PMID:17671368;PMID:18776672 -2.7.1.163 * streptomyces hygroscopicus 42000.0 1 PMID:3026810 -2.7.1.164 * methanocaldococcus jannaschii 29500.0 1 PMID:20705242 -2.7.1.164 * naegleria gruberi 33243.0 1 PMID:23603359 -2.7.1.165 * hyphomicrobium methylovorum 52000.0 2 PMID:1336459 -2.7.1.165 * picrophilus oshimae 95000.0 4 PMID:16684110 -2.7.1.165 * pyrococcus horikoshii 100000.0 6 PMID:17563835 -2.7.1.165 * saccharolobus solfataricus 90000.0 4 PMID:23279921 -2.7.1.165 * sulfurisphaera tokodaii 80000.0 2 PMID:19690808 -2.7.1.165 * thermoplasma acidophilum 49300.0 7 * -2.7.1.165 * thermoproteus tenax 48300.0 2 PMID:17764545 -2.7.1.165 * thermotoga maritima 44589.0 1 PMID:16865707 -2.7.1.167 * escherichia coli 83000.0 2 PMID:12101286;PMID:16030223 -2.7.1.167 * salmonella enterica subsp. enterica serovar typhimurium 53000.0 1 PMID:12441667 -2.7.1.169 * thermococcus kodakarensis 34000.0 2 PMID:19666462 -2.7.1.17 * arabidopsis thaliana 61830.0 1 PMID:16920870 -2.7.1.17 * candida maltosa 68890.0 1 PMID:16834601 -2.7.1.17 * escherichia coli 110000.0 3 PMID:11168365;PMID:17123542 -2.7.1.17 * halorhabdus utahensis 133000.0 1 PMID:32761262 -2.7.1.17 * heyndrickxia coagulans 56000.0 1 PMID:27206341 -2.7.1.17 * homo sapiens 58400.0 1 PMID:23027762 -2.7.1.17 * klebsiella aerogenes 110000.0 2 PMID:6272710 -2.7.1.17 * klebsiella pneumoniae 51783.0 1 PMID:1324398 -2.7.1.17 * mucor circinelloides 65100.0 2 PMID:25163569 -2.7.1.17 * saccharococcus caldoxylosilyticus 115000.0 2 PMID:6272710 -2.7.1.17 * saccharomyces cerevisiae 68000.0 1 PMID:18066500 -2.7.1.17 * scheffersomyces stipitis 130000.0 2 * -2.7.1.17 * thermotoga maritima 60000.0 1 PMID:23584458 -2.7.1.170 * escherichia coli 40000.0 2 PMID:15901686 -2.7.1.171 * homo sapiens 35171.0 4 PMID:11016445;PMID:11522682;PMID:11975663;PMID:20009024 -2.7.1.171 * mus musculus 35032.0 2 PMID:11016445;PMID:11975663;PMID:20009024 -2.7.1.172 * homo sapiens 34412.0 1 PMID:14633848 -2.7.1.172 * mus musculus 34440.0 1 PMID:14633848 -2.7.1.172 * spinacia oleracea 25000.0 1 PMID:15705060 -2.7.1.175 * actinoplanes missouriensis 62000.0 3 PMID:12879214;PMID:15378530 -2.7.1.175 * mycobacterium tuberculosis 470000.0 3 PMID:23901909 -2.7.1.175 * mycobacterium tuberculosis variant bovis 50700.0 1 PMID:20507595 -2.7.1.175 * streptomyces coelicolor 53000.0 2 PMID:15378530 -2.7.1.177 * salmonella enterica 35000.0 3 PMID:18308727;PMID:19509296 -2.7.1.178 * saccharolobus solfataricus 72000.0 5 PMID:16330030;PMID:16794308 -2.7.1.180 * vibrio cholerae 37000.0 1 PMID:29065131 -2.7.1.181 * escherichia coli 81731.0 2 PMID:15184370;PMID:21990359 -2.7.1.187 * actinoplanes sp. 36200.0 3 PMID:22944206;PMID:8784428 -2.7.1.19 * anabaena cylindrica 72000.0 3 * -2.7.1.19 * arabidopsis thaliana 640000.0 3 PMID:16258009 -2.7.1.19 * brassica sp. 180000.0 5 * -2.7.1.19 * cereibacter sphaeroides 250000.0 1 PMID:11724566 -2.7.1.19 * chlamydomonas reinhardtii 38500.0 1 PMID:16667433 -2.7.1.19 * chlorogloeopsis fritschii 230000.0 2 PMID:10800594;PMID:4361162;PMID:4369092 -2.7.1.19 * cupriavidus necator 256000.0 5 PMID:4361162;PMID:4369092;PMID:6260209 -2.7.1.19 * heterosigma akashiwo 214000.0 2 PMID:9576802 -2.7.1.19 * monoraphidium minutum 83000.0 3 PMID:16668652;PMID:24241224 -2.7.1.19 * prochloron didemni 520000.0 3 PMID:24264746 -2.7.1.19 * rhodobacter capsulatus 230000.0 2 PMID:10800594;PMID:6251028 -2.7.1.19 * rhodoblastus acidophilus 248000.0 2 PMID:10800594 -2.7.1.19 * spinacia oleracea 90000.0 3 PMID:3004354 -2.7.1.19 * synechococcus sp. 178000.0 2 PMID:8564307 -2.7.1.19 * tetradesmus obliquus 470000.0 5 PMID:3009185 -2.7.1.19 * trieres chinensis 44000.0 1 PMID:15734914 -2.7.1.19 * triticum aestivum 83000.0 1 PMID:16668652;PMID:24241224 -2.7.1.19 * vaucheria litorea 38000.0 1 PMID:19995736 -2.7.1.190 * enterococcus faecalis 56850.0 2 PMID:3015884 -2.7.1.191 * corynebacterium glutamicum 72570.0 1 PMID:8039653 -2.7.1.191 * escherichia coli 100000.0 12 PMID:2951378;PMID:7811395;PMID:8774730 -2.7.1.191 * streptococcus salivarius 35500.0 2 PMID:10746771 -2.7.1.192 * escherichia coli 37000.0 1 PMID:15060041 -2.7.1.193 * escherichia coli 68700.0 2 PMID:3056518;PMID:3284790 -2.7.1.194 * escherichia coli 122300.0 2 PMID:25686089 -2.7.1.196 * escherichia coli 25200.0 4 PMID:10913122 -2.7.1.197 * escherichia coli 315000.0 13 PMID:1527071;PMID:2123863;PMID:2517400;PMID:2654151;PMID:368051;PMID:6350293;PMID:8431419;PMID:9551558 -2.7.1.198 * escherichia coli 54018.0 1 PMID:3553176 -2.7.1.199 * bacillus subtilis 80000.0 1 PMID:1956301 -2.7.1.199 * corynebacterium glutamicum 71543.0 1 * -2.7.1.199 * escherichia coli 106000.0 3 PMID:21621292;PMID:3023349 -2.7.1.199 * salmonella enterica subsp. enterica serovar typhimurium 43000.0 1 PMID:3029764 -2.7.1.2 * aeropyrum pernix 35000.0 1 PMID:12761185 -2.7.1.2 * bacillus subtilis 70400.0 2 PMID:15018644 -2.7.1.2 * escherichia coli 47000.0 2 PMID:7786044;PMID:9023215 -2.7.1.2 * geobacillus stearothermophilus 87000.0 3 PMID:3099754;PMID:4763322 -2.7.1.2 * leishmania major 86000.0 3 PMID:17904661 -2.7.1.2 * methylomonas methanica 213000.0 6 PMID:30769875 -2.7.1.2 * methylotuvimicrobium alcaliphilum 70000.0 1 PMID:27915410 -2.7.1.2 * paracoccus versutus 67500.0 1 * -2.7.1.2 * pyrobaculum calidifontis 31573.0 2 PMID:29275440 -2.7.1.2 * streptococcus mutans 41000.0 2 PMID:7150605 -2.7.1.2 * thermotoga maritima 75000.0 3 PMID:12814622;PMID:14553940 -2.7.1.2 * trypanosoma cruzi 86000.0 3 PMID:17904661 -2.7.1.2 * zymomonas mobilis 65000.0 2 PMID:2992451 -2.7.1.20 * babesia canis rossi 41000.0 1 PMID:10518797 -2.7.1.20 * bombyx mori 38000.0 1 PMID:31370143;PMID:6260151;PMID:6268173 -2.7.1.20 * bos taurus 42000.0 1 PMID:2992963 -2.7.1.20 * entamoeba histolytica 38000.0 1 PMID:6312825 -2.7.1.20 * homo sapiens 46000.0 7 PMID:21319802;PMID:227870;PMID:31370143;PMID:6260151;PMID:6268173 -2.7.1.20 * leishmania donovani 38250.0 3 PMID:3032935 -2.7.1.20 * lupinus luteus 40000.0 2 PMID:41481 -2.7.1.20 * mus musculus 56000.0 3 PMID:15317590;PMID:6244278 -2.7.1.20 * mycobacterium tuberculosis 136000.0 5 PMID:14594827 -2.7.1.20 * nicotiana tabacum 40000.0 5 PMID:12505160;PMID:15731114 -2.7.1.20 * oryctolagus cuniculus 51000.0 3 PMID:218933;PMID:4290214 -2.7.1.20 * physcomitrium patens 37300.0 1 PMID:9680981 -2.7.1.20 * prunus persica 434000.0 2 * -2.7.1.20 * rattus norvegicus 52000.0 4 PMID:2986372;PMID:31370143;PMID:6260151;PMID:6268173;PMID:72532 -2.7.1.20 * saccharomyces cerevisiae 38500.0 3 PMID:12883639;PMID:5092557 -2.7.1.20 * toxoplasma gondii 75000.0 3 PMID:10666633;PMID:15857605 -2.7.1.201 * escherichia coli 52308.0 2 PMID:7608078 -2.7.1.202 * bacillus subtilis 18494.0 1 PMID:9551099 -2.7.1.202 * escherichia coli 57500.0 1 PMID:3076173 -2.7.1.202 * salmonella enterica subsp. enterica serovar typhimurium 47000.0 1 PMID:2546043 -2.7.1.205 * geobacillus stearothermophilus 48805.0 1 PMID:8407820 -2.7.1.206 * klebsiella pneumoniae 29370.0 8 PMID:7700234 -2.7.1.206 * lacticaseibacillus casei 30788.0 4 PMID:10613875 -2.7.1.207 * lactococcus lactis 61562.0 1 PMID:2125052 -2.7.1.207 * staphylococcus aureus 62688.0 2 PMID:2824493 -2.7.1.207 * streptococcus thermophilus 20000.0 1 PMID:9882680 -2.7.1.208 * clostridium acetobutylicum 49977.0 1 PMID:11781805 -2.7.1.21 * anolis carolinensis 57000.0 2 PMID:23351158 -2.7.1.21 * arabidopsis thaliana 52000.0 7 PMID:22897443;PMID:23351158 -2.7.1.21 * bacillus cereus 43000.0 2 PMID:23351158 -2.7.1.21 * badhamia polycephala 80000.0 1 PMID:521445 -2.7.1.21 * caenorhabditis elegans 130000.0 2 PMID:23351158 -2.7.1.21 * chlamydomonas reinhardtii 85000.0 1 * -2.7.1.21 * cryptosporidium parvum 70000.0 2 PMID:20231284 -2.7.1.21 * danio rerio 82000.0 2 PMID:23351158 -2.7.1.21 * dictyostelium discoideum 57000.0 3 PMID:15883042;PMID:23351158 -2.7.1.21 * gallus gallus 46000.0 3 PMID:23351158;PMID:3939993 -2.7.1.21 * herpes simplex virus 80000.0 3 PMID:6311815;PMID:9797227 -2.7.1.21 * herpes simplex virus type 4 38800.0 2 PMID:14527394 -2.7.1.21 * homo sapiens 340000.0 26 PMID:1063125;PMID:10924519;PMID:14690426;PMID:14697231;PMID:15153115;PMID:23351158;PMID:25881026;PMID:278906;PMID:3335503;PMID:3939993;PMID:4361106;PMID:6406493;PMID:7192285 -2.7.1.21 * human alphaherpesvirus 1 43000.0 2 * -2.7.1.21 * human alphaherpesvirus 3 80700.0 2 PMID:10733888 -2.7.1.21 * human gammaherpesvirus 4 70000.0 1 PMID:9797227 -2.7.1.21 * leishmania major 90000.0 1 PMID:25978379 -2.7.1.21 * murine gammaherpesvirus-68 68440.0 1 PMID:8638414 -2.7.1.21 * mus musculus 70000.0 8 PMID:11023833;PMID:20544521;PMID:8896760 -2.7.1.21 * rattus norvegicus 81000.0 6 PMID:1911861;PMID:23351158;PMID:4407348;PMID:692391 -2.7.1.21 * solanum lycopersicum 59000.0 3 PMID:22132978 -2.7.1.21 * tequatrovirus t4 86000.0 2 PMID:338602 -2.7.1.21 * tetrahymena thermophila 80000.0 3 PMID:1991476 -2.7.1.21 * unidentified entomopoxvirus 21200.0 1 PMID:1733099 -2.7.1.21 * xenopus tropicalis 98000.0 3 PMID:23351158 -2.7.1.211 * klebsiella pneumoniae 43000.0 1 PMID:8628219 -2.7.1.211 * salmonella enterica subsp. enterica serovar typhimurium 47500.0 1 * -2.7.1.211 * staphylococcus xylosus 50000.0 1 PMID:8232209 -2.7.1.211 * streptococcus mutans serotype c 69983.0 1 PMID:2536656 -2.7.1.211 * streptococcus sobrinus 66529.0 1 PMID:8500898 -2.7.1.214 * streptomyces hygroscopicus subsp. jinggangensis 40000.0 2 PMID:17335096 -2.7.1.218 * escherichia coli 28000.0 1 PMID:12147680 -2.7.1.22 * haemophilus influenzae 180000.0 3 PMID:12068016 -2.7.1.225 * staphylococcus aureus 61000.0 1 PMID:29483190 -2.7.1.229 * salmonella enterica subsp. enterica serovar typhimurium 67800.0 1 PMID:4376665 -2.7.1.23 * arabidopsis thaliana 110000.0 6 PMID:15247403;PMID:18391451;PMID:29662499 -2.7.1.23 * avena sativa 410000.0 2 * -2.7.1.23 * bacillus subtilis 60000.0 3 PMID:12897004;PMID:18391451 -2.7.1.23 * bos taurus 200000.0 1 PMID:11594753 -2.7.1.23 * columba sp. 270000.0 2 PMID:239 -2.7.1.23 * corynebacterium glutamicum 167500.0 4 PMID:20180116;PMID:22664190 -2.7.1.23 * corynebacterium glutamicum subsp. lactofermentum 140000.0 2 PMID:22664190 -2.7.1.23 * cyberlindnera jadinii 260000.0 2 PMID:6290285 -2.7.1.23 * entamoeba histolytica 32000.0 2 PMID:23069387 -2.7.1.23 * escherichia coli 180000.0 3 PMID:11488932;PMID:29662499 -2.7.1.23 * euglena gracilis 68000.0 1 PMID:10940642 -2.7.1.23 * giardia duodenalis 61269.0 1 * -2.7.1.23 * homo sapiens 200000.0 9 PMID:11594753;PMID:18391451;PMID:21526340;PMID:23212377;PMID:2982330 -2.7.1.23 * micrococcus flavus 39114.0 1 PMID:12951510 -2.7.1.23 * mycobacterium tuberculosis 82000.0 3 PMID:15182203 -2.7.1.23 * pyrococcus horikoshii 145000.0 4 PMID:16085824;PMID:18391451;PMID:29662499 -2.7.1.23 * saccharomyces cerevisiae 480000.0 9 PMID:15978040;PMID:18391451;PMID:221029 -2.7.1.23 * sphingomonas sp. 64000.0 2 PMID:15177293 -2.7.1.23 * sphingomonas sp. a1 32000.0 1 PMID:18391451 -2.7.1.23 * staphylococcus aureus 31000.0 1 PMID:28828348 -2.7.1.23 * strongylocentrotus purpuratus 60000.0 1 PMID:29662499 -2.7.1.23 * synechocystis sp. 31000.0 1 PMID:22056937 -2.7.1.232 * aspergillus niger 75000.0 2 PMID:12356473;PMID:26363018 -2.7.1.237 * thermococcus kodakarensis 20800.0 1 PMID:31337720 -2.7.1.24 * corynebacterium ammoniagenes 25000.0 2 PMID:11292795 -2.7.1.24 * escherichia coli 66000.0 3 PMID:11292795;PMID:12538896 -2.7.1.24 * homo sapiens 62000.0 1 PMID:11994049 -2.7.1.24 * legionella pneumophila 23600.0 1 PMID:24817720 -2.7.1.24 * mycobacterium tuberculosis 141000.0 2 PMID:21731728 -2.7.1.24 * streptomyces peucetius 28600.0 1 PMID:25022520 -2.7.1.24 * sus scrofa 118000.0 6 PMID:11994049;PMID:4018266;PMID:6312972 -2.7.1.24 * thermococcus kodakarensis 20800.0 1 PMID:31337720 -2.7.1.24 * thermus thermophilus 22700.0 1 PMID:15526298 -2.7.1.25 * arabidopsis thaliana 31977.0 3 PMID:11488606;PMID:23025382;PMID:9636674 -2.7.1.25 * chlamydomonas reinhardtii 44000.0 1 * -2.7.1.25 * escherichia coli 90000.0 6 PMID:1332767;PMID:2549047;PMID:3019265 -2.7.1.25 * geobacillus stearothermophilus 50000.0 2 * -2.7.1.25 * homo sapiens 716000.0 5 PMID:14747722;PMID:15065880;PMID:15755455 -2.7.1.25 * mycobacterium tuberculosis 42000.0 1 PMID:25807013 -2.7.1.25 * oryza sativa 26000.0 1 * -2.7.1.25 * penicillium chrysogenum 60000.0 5 PMID:12427029;PMID:2981860;PMID:2997125;PMID:6321459 -2.7.1.25 * penicillium duponti 57000.0 1 PMID:2997125 -2.7.1.25 * pyropia yezoensis 61000.0 2 * -2.7.1.25 * rattus norvegicus 58000.0 2 PMID:3032273 -2.7.1.25 * saccharomyces cerevisiae 52000.0 3 PMID:3019265 -2.7.1.25 * synechocystis sp. 40000.0 2 PMID:26294763 -2.7.1.25 * thiobacillus denitrificans 60500.0 1 PMID:19770499 -2.7.1.25 * urechis caupo 68000.0 2 PMID:8522184 -2.7.1.26 * bacillus subtilis 36000.0 3 PMID:12693963;PMID:9473052 -2.7.1.26 * corynebacterium ammoniagenes 40000.0 2 PMID:24170887;PMID:3023344 -2.7.1.26 * neurospora crassa 35500.0 1 PMID:10650711 -2.7.1.26 * rattus norvegicus 28000.0 3 PMID:2163401;PMID:6243635 -2.7.1.26 * vigna radiata var. radiata 35000.0 2 PMID:6274324 -2.7.1.29 * [candida] boidinii 139000.0 2 PMID:2177824 -2.7.1.29 * citrobacter freundii 63000.0 1 PMID:26610480 -2.7.1.29 * escherichia coli 52000.0 1 PMID:11350937 -2.7.1.29 * homo sapiens 59400.0 1 PMID:16289032 -2.7.1.29 * komagataella pastoris 65300.0 1 PMID:9675820 -2.7.1.29 * saccharomyces cerevisiae 115000.0 2 PMID:12401799 -2.7.1.29 * schizosaccharomyces pombe 145000.0 3 PMID:10091325 -2.7.1.3 * bos taurus 56000.0 2 PMID:193556 -2.7.1.3 * felis catus 33000.0 1 PMID:19108855 -2.7.1.3 * haloarcula vallismortis 100000.0 2 PMID:8071229 -2.7.1.3 * homo sapiens 75000.0 4 PMID:16372272;PMID:2996495 -2.7.1.30 * candida mycoderma 251000.0 1 * -2.7.1.30 * cellulomonas sp. 128000.0 1 PMID:27112401;PMID:28284306 -2.7.1.30 * cucumis sativus 210000.0 1 PMID:3032191 -2.7.1.30 * debaryomyces hansenii 236000.0 1 * -2.7.1.30 * elizabethkingia meningoseptica 200000.0 2 PMID:9972265 -2.7.1.30 * escherichia coli 391000.0 8 PMID:17441732;PMID:21550976;PMID:5335908 -2.7.1.30 * geobacillus stearothermophilus 230000.0 2 * -2.7.1.30 * haemophilus influenzae 56000.0 1 PMID:11388799 -2.7.1.30 * nannizzia gypsea 45000.0 1 PMID:6325842 -2.7.1.30 * neurospora crassa 140000.0 2 PMID:236729 -2.7.1.30 * rattus norvegicus 58000.0 1 PMID:35161 -2.7.1.30 * saccharomyces cerevisiae 60000.0 1 * -2.7.1.30 * thermococcus kodakarensis 316000.0 4 PMID:17277457;PMID:32008925;PMID:9930671 -2.7.1.30 * thermus thermophilus 220000.0 2 * -2.7.1.30 * trypanosoma brucei 56000.0 2 PMID:10759857;PMID:2290444 -2.7.1.30 * trypanosoma brucei brucei 50000.0 1 PMID:21187682 -2.7.1.30 * trypanosoma brucei gambiense 119000.0 3 PMID:20208167;PMID:23620597 -2.7.1.30 * trypanosoma congolense 56200.0 2 PMID:21187682 -2.7.1.30 * trypanosoma vivax 54600.0 2 PMID:21187682 -2.7.1.31 * arabidopsis thaliana 39000.0 1 PMID:15980259 -2.7.1.31 * avena sativa 41000.0 1 PMID:6307152 -2.7.1.31 * brassica rapa subsp. oleifera 45000.0 1 * -2.7.1.31 * hordeum vulgare 41000.0 1 PMID:6307152 -2.7.1.31 * lathyrus oleraceus 41000.0 1 PMID:6307152 -2.7.1.31 * secale cereale 41000.0 1 PMID:6307152 -2.7.1.31 * spinacia oleracea 40000.0 2 * -2.7.1.31 * zea mays 47000.0 2 PMID:24226402 -2.7.1.32 * caenorhabditis elegans 51000.0 5 PMID:12758145;PMID:14960577 -2.7.1.32 * homo sapiens 94000.0 11 PMID:14593713;PMID:15003397;PMID:1618328;PMID:16322253;PMID:16719778;PMID:17007874;PMID:19915674;PMID:26700752;PMID:27149373 -2.7.1.32 * lathyrus oleraceus 44000.0 1 PMID:11171184 -2.7.1.32 * mus musculus 52000.0 4 PMID:14593713;PMID:15003397;PMID:16719778 -2.7.1.32 * plasmodium falciparum 56000.0 2 PMID:16626864 -2.7.1.32 * plasmodium falciparum 3d7 52000.0 1 PMID:19845508 -2.7.1.32 * rattus norvegicus 160000.0 10 PMID:1323025;PMID:1323026;PMID:1323027;PMID:15003397;PMID:16719778;PMID:2152925;PMID:2157491;PMID:6094572;PMID:7566358 -2.7.1.32 * saccharomyces cerevisiae 73000.0 6 PMID:16719778;PMID:4572730;PMID:9506987 -2.7.1.32 * schizosaccharomyces pombe 52000.0 1 PMID:16719778 -2.7.1.32 * toxoplasma gondii 70000.0 3 PMID:22451671 -2.7.1.32 * trypanosoma brucei 72610.0 1 PMID:18489261 -2.7.1.33 * arabidopsis thaliana 99600.0 1 PMID:16897480 -2.7.1.33 * aspergillus nidulans 46900.0 1 PMID:9890959 -2.7.1.33 * corynebacterium ammoniagenes 45000.0 1 * -2.7.1.33 * drosophila melanogaster 56700.0 2 PMID:11238410 -2.7.1.33 * escherichia coli 36300.0 3 PMID:16699190;PMID:16701556 -2.7.1.33 * homo sapiens 63000.0 3 PMID:15659606;PMID:16437574 -2.7.1.33 * mus musculus 41600.0 2 PMID:16040613 -2.7.1.33 * mycobacterium tuberculosis 37500.0 1 PMID:16508093 -2.7.1.33 * picrophilus oshimae 33000.0 1 PMID:19854913 -2.7.1.33 * staphylococcus aureus 59000.0 3 PMID:12760898;PMID:15548531 -2.7.1.33 * streptomyces peucetius 52000.0 2 PMID:21193825 -2.7.1.35 * bacillus subtilis 40000.0 1 PMID:17012797 -2.7.1.35 * bombyx mori 68000.0 3 PMID:17707212 -2.7.1.35 * bos taurus 80000.0 2 PMID:3015616;PMID:3022816;PMID:8384299 -2.7.1.35 * homo sapiens 65000.0 4 PMID:10987144;PMID:15820755;PMID:238769;PMID:25157434 -2.7.1.35 * ovis aries 80000.0 4 PMID:10395444;PMID:3015616;PMID:3022816;PMID:6285827;PMID:8384299 -2.7.1.35 * plasmodium falciparum 110000.0 3 PMID:15590634 -2.7.1.35 * plasmodium vivax 35000.0 1 PMID:25157434 -2.7.1.35 * schistosoma mansoni 37773.0 1 PMID:33613557 -2.7.1.35 * sus scrofa 40000.0 1 PMID:14688239 -2.7.1.35 * trypanosoma brucei 73000.0 3 PMID:22857512;PMID:9274862 -2.7.1.35 * trypanosoma cruzi 35000.0 1 PMID:25157434 -2.7.1.36 * aedes aegypti 43270.0 1 PMID:26566274 -2.7.1.36 * arabidopsis thaliana 41000.0 1 * -2.7.1.36 * bacopa monnieri 46000.0 1 PMID:25281875 -2.7.1.36 * catharanthus roseus 104600.0 3 PMID:10860546 -2.7.1.36 * cucumis melo 103500.0 1 PMID:4361551 -2.7.1.36 * enterococcus faecalis 71100.0 3 PMID:14767074 -2.7.1.36 * gallus gallus 100000.0 1 PMID:4361551 -2.7.1.36 * hevea brasiliensis 102000.0 1 PMID:4361551 -2.7.1.36 * homo sapiens 78000.0 3 PMID:21908638;PMID:9038186;PMID:9325256;PMID:9392419 -2.7.1.36 * methanocaldococcus jannaschii 68000.0 2 PMID:10497066 -2.7.1.36 * methanosarcina mazei 78000.0 5 PMID:21908638;PMID:23192048;PMID:9325256 -2.7.1.36 * oryctolagus cuniculus 100000.0 1 PMID:4361551 -2.7.1.36 * phaseolus vulgaris 104000.0 2 PMID:4361551;PMID:4723778 -2.7.1.36 * rattus norvegicus 86000.0 8 PMID:11111075;PMID:12509999;PMID:14680942;PMID:2153681;PMID:9038186;PMID:9325256 -2.7.1.36 * saccharolobus solfataricus 37000.0 1 PMID:23378249 -2.7.1.36 * saccharomyces cerevisiae 103500.0 1 PMID:4361551 -2.7.1.36 * sarcophaga bullata 113000.0 1 * -2.7.1.36 * staphylococcus aureus 34500.0 2 PMID:14679225 -2.7.1.36 * sus scrofa 104000.0 3 PMID:2991706;PMID:6311270 -2.7.1.36 * trypanosoma cruzi 34000.0 1 PMID:27113535 -2.7.1.39 * [brevibacterium] flavum 55000.0 1 PMID:5016260 -2.7.1.39 * escherichia coli 60000.0 2 PMID:177283;PMID:4364023 -2.7.1.39 * rhodospirillum rubrum 145000.0 1 * -2.7.1.39 * saccharomyces cerevisiae 73000.0 2 PMID:2165904 -2.7.1.39 * triticum aestivum 75000.0 2 * -2.7.1.4 * beta vulgaris 70000.0 2 PMID:11120475 -2.7.1.4 * bifidobacterium longum 35000.0 2 PMID:15375133 -2.7.1.4 * entamoeba histolytica 35000.0 2 PMID:25700717 -2.7.1.4 * escherichia coli 39000.0 1 PMID:1809835 -2.7.1.4 * glycine max 84000.0 1 PMID:16664355 -2.7.1.4 * hordeum vulgare 73000.0 2 * -2.7.1.4 * klebsiella pneumoniae 34000.0 1 PMID:1809835 -2.7.1.4 * lactococcus lactis 60000.0 3 PMID:1658003 -2.7.1.4 * lathyrus oleraceus 72000.0 1 PMID:6091556 -2.7.1.4 * leuconostoc mesenteroides 47000.0 1 * -2.7.1.4 * mycolicibacterium phlei 54300.0 1 PMID:6303235 -2.7.1.4 * persea americana 85000.0 1 PMID:11120475 -2.7.1.4 * pseudomonas sp. 75000.0 2 * -2.7.1.4 * rhizobium leguminosarum 36500.0 1 PMID:8932706 -2.7.1.4 * saccharum sp. 69000.0 3 * -2.7.1.4 * solanum lycopersicum 73000.0 4 PMID:9325137 -2.7.1.4 * solanum tuberosum 118000.0 5 PMID:16652943 -2.7.1.4 * streptomyces violaceoruber 80000.0 3 PMID:164228 -2.7.1.4 * thermococcus litoralis 58000.0 3 PMID:15138858 -2.7.1.4 * zea mays 59000.0 3 PMID:16666661 -2.7.1.40 * acanthocardia tuberculata 282000.0 2 * -2.7.1.40 * aeropyrum pernix 207000.0 2 PMID:12654928 -2.7.1.40 * arabidopsis thaliana 476000.0 4 PMID:17557808 -2.7.1.40 * archaeoglobus fulgidus 203000.0 2 PMID:10715009;PMID:12654928 -2.7.1.40 * aspergillus nidulans 65000.0 1 PMID:3058273 -2.7.1.40 * bacillus licheniformis 220000.0 2 PMID:7549104 -2.7.1.40 * bacillus sp. (in: firmicutes) 62200.0 1 * -2.7.1.40 * bos taurus 230000.0 4 PMID:2591636;PMID:3970531 -2.7.1.40 * brassica napus 380000.0 3 PMID:10880971;PMID:11913971 -2.7.1.40 * brassica rapa subsp. oleifera 214000.0 3 PMID:10983413 -2.7.1.40 * brochothrix thermosphacta 58000.0 1 PMID:1772447 -2.7.1.40 * busycotypus canaliculatum 299800.0 7 PMID:4062301;PMID:6468395 -2.7.1.40 * canis lupus familiaris 69900.0 1 PMID:6781948 -2.7.1.40 * chlamydia trachomatis 53500.0 1 PMID:11994161 -2.7.1.40 * chlamydomonas reinhardtii 224000.0 2 PMID:12632162;PMID:12798948 -2.7.1.40 * cicer arietinum 200000.0 1 PMID:11238975 -2.7.1.40 * concholepas concholepas 234000.0 3 PMID:1772447 -2.7.1.40 * corynebacterium glutamicum 430881.0 1 PMID:27852252 -2.7.1.40 * cynodon dactylon 200000.0 2 PMID:11238975 -2.7.1.40 * dictyostelium discoideum 66000.0 1 PMID:2241987 -2.7.1.40 * eimeria tenella 57590.0 2 PMID:17030033 -2.7.1.40 * entamoeba histolytica 70000.0 1 PMID:31676451 -2.7.1.40 * equus caballus 58000.0 1 PMID:18602015 -2.7.1.40 * escherichia coli 240000.0 7 PMID:19800933 -2.7.1.40 * geobacillus stearothermophilus 250000.0 2 PMID:11238975;PMID:3467680;PMID:3711058 -2.7.1.40 * glycine max 230000.0 2 PMID:12798948;PMID:16049677 -2.7.1.40 * halobacterium salinarum 300000.0 2 * -2.7.1.40 * homo sapiens 240000.0 12 PMID:11698298;PMID:16666032;PMID:18337815;PMID:18362474;PMID:19308990;PMID:23576436;PMID:31760602;PMID:7073710 -2.7.1.40 * kinixys erosa 49680.0 1 * -2.7.1.40 * lactococcus lactis 235000.0 1 * -2.7.1.40 * leishmania donovani 54400.0 1 PMID:18725273 -2.7.1.40 * leishmania major 181000.0 2 PMID:3344004 -2.7.1.40 * lethenteron camtschaticum 232000.0 2 PMID:11163314;PMID:1815584 -2.7.1.40 * microbispora rosea subsp. aerata 270000.0 2 PMID:7436410;PMID:9028035 -2.7.1.40 * monoraphidium minutum 590000.0 5 PMID:2916839 -2.7.1.40 * mucor racemosus 239000.0 5 PMID:3611022 -2.7.1.40 * mus musculus 238000.0 7 PMID:18191611;PMID:6784752 -2.7.1.40 * musa cavendishii 240000.0 2 PMID:11698298;PMID:12632162;PMID:12798948;PMID:16666032;PMID:7073710 -2.7.1.40 * mycolicibacterium smegmatis 230700.0 1 PMID:6614924 -2.7.1.40 * mytilus galloprovincialis 300000.0 1 * -2.7.1.40 * oryctolagus cuniculus 250000.0 4 PMID:19169653;PMID:23324382 -2.7.1.40 * parachlorella kessleri 580000.0 2 * -2.7.1.40 * patella caerulea 238000.0 1 * -2.7.1.40 * periplaneta americana 235000.0 1 * -2.7.1.40 * pigeon 152000.0 1 PMID:2758802 -2.7.1.40 * plasmodium falciparum 80000.0 1 PMID:15567170 -2.7.1.40 * platichthys flesus 2000000.0 3 PMID:6509936 -2.7.1.40 * pyrobaculum aerophilum 205000.0 2 PMID:12654928 -2.7.1.40 * rattus norvegicus 250000.0 5 PMID:11698298;PMID:16666032;PMID:18602720;PMID:2591636;PMID:3970531;PMID:7073710;PMID:7115773 -2.7.1.40 * rhodotorula toruloides 190000.0 1 * -2.7.1.40 * ricinus communis 305000.0 8 PMID:11698298;PMID:12798948;PMID:16049677;PMID:16666032;PMID:16667885;PMID:7073710;PMID:8806784 -2.7.1.40 * saccharolobus solfataricus 50000.0 2 * -2.7.1.40 * saccharomyces cerevisiae 209400.0 2 PMID:16426231 -2.7.1.40 * saccharomyces pastorianus 190000.0 1 * -2.7.1.40 * salmonella enterica subsp. enterica serovar typhimurium 220000.0 4 PMID:3297035 -2.7.1.40 * schizosaccharomyces pombe 170000.0 3 PMID:9790887 -2.7.1.40 * selenomonas ruminantium 250000.0 3 PMID:11238975;PMID:3467680;PMID:3711058 -2.7.1.40 * solanum tuberosum 58000.0 1 PMID:25573389 -2.7.1.40 * sporosarcina psychrophila 62570.0 1 PMID:7549104 -2.7.1.40 * staphylococcus aureus 250000.0 1 PMID:20707314 -2.7.1.40 * streptococcus mutans 190000.0 2 PMID:7054143 -2.7.1.40 * sus scrofa 265000.0 10 PMID:11163314;PMID:11238975;PMID:17641091;PMID:1815584;PMID:20026031;PMID:3467680;PMID:3711058;PMID:7584599 -2.7.1.40 * synechococcus sp. 280000.0 2 PMID:11294847 -2.7.1.40 * takifugu rubripes 230000.0 2 PMID:12632162;PMID:12798948;PMID:16049677 -2.7.1.40 * thermoplasma acidophilum 250000.0 1 * -2.7.1.40 * thermoproteus tenax 200000.0 2 PMID:10715009;PMID:12654928 -2.7.1.40 * thermotoga maritima 194000.0 4 PMID:12654928 -2.7.1.40 * toxoplasma gondii 240000.0 3 PMID:12632162;PMID:12798948;PMID:18326043 -2.7.1.40 * trypanosoma brucei 270000.0 1 PMID:7436410;PMID:9028035 -2.7.1.40 * vibrio cholerae serotype o1 200000.0 2 PMID:28686591 -2.7.1.40 * yersinia enterocolitica 51500.0 2 PMID:23384479 -2.7.1.40 * zymomonas mobilis 115000.0 3 PMID:3026343 -2.7.1.41 * bacillus subtilis 28000.0 2 PMID:11081794 -2.7.1.43 * arabidopsis thaliana 40000.0 1 PMID:19951951 -2.7.1.43 * danio rerio 70000.0 1 PMID:24586965 -2.7.1.43 * lilium longiflorum 40000.0 1 PMID:19951951 -2.7.1.45 * sulfurisphaera tokodaii 120000.0 7 PMID:17407821 -2.7.1.45 * thermoplasma acidophilum 260000.0 3 * -2.7.1.45 * thermotoga maritima 37601.0 1 PMID:18004772 -2.7.1.45 * thermus thermophilus 160000.0 1 PMID:15210349 -2.7.1.46 * arabidopsis thaliana 100000.0 2 PMID:27145098 -2.7.1.47 * klebsiella aerogenes 116000.0 4 PMID:220218;PMID:6272710 -2.7.1.48 * arabidopsis thaliana 53000.0 1 PMID:17143579 -2.7.1.48 * entamoeba histolytica 40000.0 1 PMID:19368743 -2.7.1.48 * escherichia coli 90000.0 3 PMID:211379;PMID:25160914 -2.7.1.48 * geobacillus stearothermophilus 109000.0 1 PMID:4337192 -2.7.1.48 * homo sapiens 120000.0 6 PMID:11306702;PMID:15130468;PMID:15280220 -2.7.1.48 * lactobacillus delbrueckii subsp. bulgaricus 24000.0 2 PMID:25160914 -2.7.1.48 * mus musculus 160000.0 3 PMID:166617;PMID:211380;PMID:2991280;PMID:4696063 -2.7.1.49 * escherichia coli 44000.0 5 PMID:10075431;PMID:2540841 -2.7.1.49 * plasmodium falciparum 35000.0 1 PMID:16497163 -2.7.1.49 * saccharomyces cerevisiae 65000.0 1 PMID:15614489 -2.7.1.49 * zea mays 95000.0 3 PMID:17696876 -2.7.1.5 * escherichia coli 54110.0 4 PMID:16674975;PMID:2558952 -2.7.1.50 * escherichia coli 28100.0 2 PMID:26634770 -2.7.1.50 * pyrococcus horikoshii ot3 28950.0 1 PMID:19851002 -2.7.1.50 * saccharomyces cerevisiae 470000.0 2 PMID:8394314 -2.7.1.52 * arabidopsis thaliana 120000.0 2 PMID:18199744 -2.7.1.52 * bacteroides fragilis 440000.0 4 PMID:25195892;PMID:30242642;PMID:9488699 -2.7.1.52 * canis lupus familiaris 494000.0 1 PMID:20962 -2.7.1.52 * homo sapiens 110000.0 1 PMID:12056818 -2.7.1.52 * mortierella alpina 49000.0 1 PMID:26957583 -2.7.1.52 * mus musculus 120000.0 2 PMID:14686921 -2.7.1.52 * sus scrofa 440000.0 4 PMID:30242642;PMID:40602;PMID:9488699 -2.7.1.52 * vitis vinifera 118800.0 1 PMID:22949207 -2.7.1.56 * clostridium pasteurianum 63200.0 7 PMID:4280969 -2.7.1.56 * escherichia coli 57000.0 3 PMID:10833389 -2.7.1.56 * haloarcula vallismortis 76000.0 1 PMID:7918573 -2.7.1.56 * haloferax volcanii 70000.0 2 PMID:22493022 -2.7.1.56 * klebsiella aerogenes 75000.0 1 PMID:237207;PMID:4242639 -2.7.1.58 * haloferax volcanii 194000.0 3 PMID:25287957 -2.7.1.58 * klebsiella pneumoniae 31100.0 1 PMID:21795809 -2.7.1.59 * arabidopsis thaliana 35000.0 1 PMID:26408204 -2.7.1.59 * candida albicans 75000.0 1 PMID:6250622 -2.7.1.59 * clostridium acetobutylicum 34329.0 1 PMID:21784936 -2.7.1.59 * homo sapiens 374000.0 2 PMID:10824116;PMID:4365241 -2.7.1.59 * mus musculus 373000.0 4 PMID:10824116;PMID:12199699 -2.7.1.59 * rattus norvegicus 80000.0 5 PMID:24625575;PMID:24722415;PMID:6248025;PMID:9523722 -2.7.1.6 * bifidobacterium bifidum 48000.0 3 * -2.7.1.6 * bifidobacterium longum subsp. infantis 45000.0 1 PMID:22633137 -2.7.1.6 * cricetulus griseus 60000.0 1 PMID:6617655;PMID:7117670 -2.7.1.6 * homo sapiens 58000.0 6 PMID:4052432;PMID:4943674;PMID:5028074 -2.7.1.6 * leminorella grimontii 40000.0 1 PMID:29193544 -2.7.1.6 * mycobacterium sp. 41700.0 1 PMID:6189374 -2.7.1.6 * pyrococcus furiosus 40000.0 1 PMID:14501125 -2.7.1.6 * rattus norvegicus 43000.0 1 PMID:19433218 -2.7.1.6 * saccharomyces cerevisiae 60000.0 2 PMID:14144 -2.7.1.6 * streptococcus pneumoniae 37000.0 1 PMID:22513283 -2.7.1.6 * tetrahymena thermophila 55000.0 2 PMID:7104394 -2.7.1.6 * trichoderma reesei 57000.0 1 PMID:14763977 -2.7.1.6 * trypanosoma cruzi 51900.0 4 PMID:27312997 -2.7.1.6 * vicia faba 60000.0 2 PMID:6617655;PMID:7117670 -2.7.1.60 * homo sapiens 80000.0 5 PMID:10431835;PMID:10824116;PMID:15147877;PMID:15748884;PMID:19845164 -2.7.1.60 * mus musculus 79200.0 4 PMID:10103025;PMID:10824116;PMID:15748884 -2.7.1.60 * rattus norvegicus 500000.0 11 PMID:10497249;PMID:15135418;PMID:15330759;PMID:17448495;PMID:9305887 -2.7.1.60 * staphylococcus aureus 62000.0 2 PMID:24817729;PMID:31949045 -2.7.1.61 * klebsiella aerogenes 150000.0 1 PMID:196625 -2.7.1.63 * acidipropionibacterium acidipropionici 30000.0 1 PMID:10448674 -2.7.1.63 * anabaena sp. 26600.0 2 PMID:25320362 -2.7.1.63 * corynebacterium glutamicum 67800.0 3 PMID:15668011;PMID:20379711 -2.7.1.63 * methylomonas methanica 30000.0 3 PMID:30769875 -2.7.1.63 * microlunatus phosphovorus 64000.0 3 PMID:12949120 -2.7.1.63 * mycobacterium tuberculosis 66000.0 4 PMID:10448674;PMID:8617763 -2.7.1.63 * mycolicibacterium phlei 280000.0 3 PMID:14212975 -2.7.1.63 * nocardia minima 59000.0 1 PMID:89794 -2.7.1.63 * nostoc sp. 39000.0 3 PMID:25320362 -2.7.1.63 * propionibacterium freudenreichii subsp. shermanii 63000.0 4 PMID:10448674 -2.7.1.63 * streptomyces coelicolor 200000.0 2 PMID:24200789 -2.7.1.64 * thermococcus kodakarensis 30300.0 1 PMID:23737529 -2.7.1.66 * staphylococcus aureus 17000.0 2 PMID:4374629;PMID:5057461;PMID:5289877 -2.7.1.66 * streptococcus mutans 17000.0 1 PMID:22224599 -2.7.1.67 * arabidopsis thaliana 126000.0 1 PMID:16649109 -2.7.1.67 * bos taurus 230000.0 8 PMID:11526106;PMID:1652438;PMID:17494916;PMID:2540742;PMID:2827737;PMID:2837470;PMID:2851325;PMID:3036072 -2.7.1.67 * daucus carota 83000.0 2 PMID:12228376 -2.7.1.67 * homo sapiens 550000.0 16 PMID:1652438;PMID:1657176;PMID:16606619;PMID:17088255;PMID:2171662;PMID:22750097;PMID:24920820;PMID:2837470;PMID:2851325;PMID:28864297;PMID:3036072 -2.7.1.67 * mus musculus 60000.0 1 PMID:3014004 -2.7.1.67 * oryza sativa 46730.0 2 PMID:16649109 -2.7.1.67 * ovis aries 150000.0 2 PMID:10549154;PMID:1322897;PMID:1655428;PMID:2830904 -2.7.1.67 * rattus norvegicus 80000.0 3 PMID:10549154;PMID:1322897;PMID:1655428;PMID:2830904;PMID:2846568 -2.7.1.67 * saccharomyces cerevisiae 230000.0 9 PMID:10549154;PMID:1322897;PMID:1323031;PMID:1331109;PMID:16365163;PMID:1655428;PMID:16793271;PMID:2830904;PMID:2848810 -2.7.1.67 * spinacia oleracea 120000.0 2 PMID:10517842 -2.7.1.67 * sus scrofa 55000.0 1 PMID:10549154;PMID:1322897;PMID:1655428;PMID:2830904 -2.7.1.67 * trypanosoma brucei 66000.0 1 PMID:17483288 -2.7.1.68 * bos taurus 110000.0 1 PMID:2152796 -2.7.1.68 * eimeria tenella 28170.0 1 PMID:17688436 -2.7.1.68 * homo sapiens 237000.0 8 PMID:1323032;PMID:15464023;PMID:15994099;PMID:16448788;PMID:23602387;PMID:2538472;PMID:26157143 -2.7.1.68 * mus musculus 90000.0 3 PMID:15464023;PMID:25152467 -2.7.1.68 * ovis aries 130000.0 2 PMID:8744418 -2.7.1.68 * rattus norvegicus 75600.0 2 PMID:14741049;PMID:6093768 -2.7.1.68 * schizosaccharomyces pombe 63000.0 1 PMID:9873063 -2.7.1.7 * arthrobacter sp. 30000.0 1 PMID:12839753 -2.7.1.7 * leuconostoc mesenteroides 47000.0 1 * -2.7.1.7 * streptomyces sp. 50000.0 1 PMID:6289902 -2.7.1.71 * acinetobacter baumannii 21500.0 1 PMID:26249354 -2.7.1.71 * cyberlindnera fabianii 14000.0 1 PMID:6270920 -2.7.1.71 * cyberlindnera jadinii 14000.0 1 PMID:6270920 -2.7.1.71 * escherichia coli 21400.0 3 PMID:3001029;PMID:3037263 -2.7.1.71 * helicobacter pylori 20000.0 1 PMID:16291688 -2.7.1.71 * lodderomyces elongisporus 13000.0 1 PMID:6270920 -2.7.1.71 * meyerozyma guilliermondii 13000.0 1 PMID:6270920 -2.7.1.71 * mycobacterium tuberculosis 20700.0 3 PMID:17348838;PMID:23671579 -2.7.1.71 * ogataea henricii 13000.0 1 PMID:6270920 -2.7.1.71 * salmonella enterica subsp. enterica serovar typhimurium 30000.0 1 PMID:4866525 -2.7.1.71 * senna obtusifolia 33630.0 1 * -2.7.1.71 * spinacia oleracea 31000.0 2 PMID:16667533 -2.7.1.71 * wickerhamomyces anomalus 14000.0 1 PMID:6270920 -2.7.1.72 * escherichia coli 31400.0 2 PMID:24248535 -2.7.1.72 * streptomyces griseus 38000.0 2 PMID:6313852 -2.7.1.73 * escherichia coli 85000.0 3 PMID:10879466;PMID:7665468 -2.7.1.74 * bos taurus 56000.0 1 PMID:211383;PMID:5442271 -2.7.1.74 * homo sapiens 70000.0 16 PMID:12744604;PMID:16361699;PMID:16401075;PMID:1657002;PMID:18258203;PMID:2539852;PMID:27280468;PMID:2844225;PMID:2845988;PMID:51655;PMID:5687717;PMID:8399394;PMID:9342227 -2.7.1.74 * lactobacillus acidophilus 29000.0 2 PMID:8172906 -2.7.1.74 * mus musculus 60000.0 2 PMID:12744604;PMID:1657002;PMID:2539852;PMID:2844225;PMID:5687717;PMID:9342227 -2.7.1.76 * bacillus cereus 26200.0 1 PMID:17615154 -2.7.1.76 * bos taurus 63000.0 1 PMID:5554289 -2.7.1.76 * dictyostelium discoideum 28600.0 1 PMID:17448496 -2.7.1.76 * lactobacillus acidophilus 29000.0 2 PMID:8172906 -2.7.1.76 * mycoplasma mycoides 50000.0 4 PMID:11737647;PMID:17229440 -2.7.1.76 * staphylococcus aureus 26400.0 1 PMID:17526755 -2.7.1.77 * daucus carota 44000.0 1 PMID:5055776;PMID:692392 -2.7.1.77 * hordeum vulgare 55000.0 4 PMID:3013235;PMID:6279651 -2.7.1.77 * leishmania tropica 40000.0 1 * -2.7.1.77 * lupinus luteus 72000.0 1 PMID:465504 -2.7.1.77 * morganella morganii 160000.0 2 PMID:16232546 -2.7.1.77 * pantoea agglomerans 68000.0 1 PMID:1083386 -2.7.1.78 * bos taurus 72000.0 4 PMID:23843;PMID:6263631;PMID:7642718 -2.7.1.78 * homo sapiens 58000.0 4 PMID:14556639;PMID:19773431;PMID:24766810 -2.7.1.78 * kostyavirus cjw1 160000.0 2 PMID:15056675 -2.7.1.78 * mus musculus 96000.0 2 PMID:6090142 -2.7.1.78 * omegavirus omega 160000.0 2 PMID:15056675 -2.7.1.78 * pyrococcus horikoshii 41000.0 1 PMID:19299550 -2.7.1.78 * rattus norvegicus 80000.0 5 PMID:19082984;PMID:241638;PMID:2828058;PMID:2986715;PMID:3504;PMID:9027586 -2.7.1.78 * tequatrovirus t4 140000.0 4 PMID:19082984;PMID:191256;PMID:4366077 -2.7.1.78 * unidentified baculovirus 80000.0 1 PMID:14747466 -2.7.1.8 * vibrio cholerae serotype o1 31600.0 2 PMID:11850417 -2.7.1.80 * propionibacterium freudenreichii subsp. shermanii 65000.0 1 PMID:4337852 -2.7.1.82 * arabidopsis thaliana 40000.0 1 PMID:25966764 -2.7.1.82 * culex quinquefasciatus 44000.0 1 PMID:6263190 -2.7.1.82 * glycine max 37000.0 2 PMID:228735 -2.7.1.82 * homo sapiens 87000.0 2 PMID:2167130;PMID:9370318 -2.7.1.82 * mus musculus 47000.0 2 PMID:11964179 -2.7.1.82 * plasmodium falciparum 3d7 109000.0 2 PMID:19845508 -2.7.1.82 * rattus norvegicus 190000.0 6 PMID:4373031;PMID:9370318;PMID:9421192 -2.7.1.82 * spinacia oleracea 110000.0 1 PMID:187122 -2.7.1.82 * trypanosoma brucei 140000.0 6 PMID:18489261 -2.7.1.85 * klebsiella aerogenes 150000.0 1 PMID:5030625 -2.7.1.85 * klebsiella pneumoniae 33000.0 2 PMID:12110692 -2.7.1.85 * listeria innocua 32000.0 1 PMID:12110692 -2.7.1.85 * listeria monocytogenes 32000.0 1 PMID:12110692 -2.7.1.86 * arabidopsis thaliana 78000.0 5 PMID:15347288;PMID:15711971;PMID:18391451 -2.7.1.86 * aspergillus nidulans 49000.0 1 PMID:18840540 -2.7.1.86 * fusarium oxysporum 156000.0 2 * -2.7.1.86 * saccharomyces cerevisiae 160000.0 6 PMID:18391451;PMID:21730068;PMID:23053084;PMID:2547755;PMID:29662499 -2.7.1.87 * streptomyces griseus 29000.0 1 PMID:2844130 -2.7.1.89 * salmonella enterica 34000.0 1 PMID:17693493 -2.7.1.90 * acholeplasma laidlawii 81000.0 2 PMID:3001032 -2.7.1.90 * ananas comosus 97000.0 2 PMID:12223643 -2.7.1.90 * brassica nigra 520000.0 4 PMID:8819330 -2.7.1.90 * daucus carota 294000.0 2 * -2.7.1.90 * dictyoglomus thermophilum 65000.0 2 PMID:10356999 -2.7.1.90 * entamoeba histolytica 83000.0 2 PMID:178659 -2.7.1.90 * giardia duodenalis 67000.0 2 PMID:7663168 -2.7.1.90 * glycine max 183000.0 2 PMID:24241857 -2.7.1.90 * hexamita inflata 70000.0 2 PMID:9497064 -2.7.1.90 * methylobacterium nodulans 180000.0 2 PMID:20868748;PMID:22803946 -2.7.1.90 * methylococcus capsulatus 90000.0 2 PMID:1331784;PMID:19054082 -2.7.1.90 * methylosinus trichosporium 270000.0 2 PMID:22803946 -2.7.1.90 * methylotuvimicrobium alcaliphilum 180000.0 3 PMID:20868748;PMID:22803946 -2.7.1.90 * musa cavendishii 490000.0 3 PMID:12721855 -2.7.1.90 * naegleria fowleri 180000.0 2 PMID:20868748;PMID:22803946 -2.7.1.90 * oryza sativa 103000.0 2 * -2.7.1.90 * phaseolus coccineus 450000.0 2 PMID:2825454 -2.7.1.90 * propionibacterium freudenreichii 43243.0 1 PMID:1653240 -2.7.1.90 * propionibacterium freudenreichii subsp. shermanii 95000.0 2 PMID:171261 -2.7.1.90 * rhodospirillum rubrum 95000.0 1 * -2.7.1.90 * saccharum hybrid cultivar 511000.0 5 * -2.7.1.90 * sansevieria trifasciata 125000.0 2 PMID:2825454 -2.7.1.90 * solanum lycopersicum 425000.0 6 * -2.7.1.90 * solanum tuberosum 265000.0 5 PMID:16665962;PMID:3038023 -2.7.1.90 * thermoproteus tenax 100000.0 2 PMID:11265483;PMID:1331784 -2.7.1.90 * toxoplasma gondii 100000.0 2 PMID:11265483;PMID:1331784;PMID:19054082 -2.7.1.90 * triticum aestivum 170000.0 3 PMID:16667036 -2.7.1.90 * vigna radiata 190000.0 1 PMID:3021198 -2.7.1.90 * xanthomonas campestris pv. campestris 45000.0 2 PMID:24508689 -2.7.1.90 * zea mays 260000.0 3 PMID:22158678 -2.7.1.91 * bos taurus 190000.0 1 PMID:181377 -2.7.1.91 * homo sapiens 65200.0 8 PMID:16368679;PMID:16571380;PMID:16916784;PMID:17064696;PMID:17482291;PMID:17519232;PMID:23000541 -2.7.1.91 * mus musculus 43300.0 4 PMID:16368679;PMID:17519232 -2.7.1.91 * rattus norvegicus 96000.0 6 PMID:17200676;PMID:17912702;PMID:18028875;PMID:9575218 -2.7.1.92 * klebsiella aerogenes 225000.0 1 PMID:4328832 -2.7.1.94 * bos taurus 72000.0 1 PMID:2550036 -2.7.10.1 * acinetobacter johnsonii 82373.0 2 PMID:8683591;PMID:9434192 -2.7.10.1 * avian erythroblastosis virus 67638.0 1 PMID:6313229 -2.7.10.1 * geodia cydonium 68710.0 1 PMID:7920862 -2.7.10.1 * homo sapiens 340000.0 23 PMID:15337524;PMID:15853662;PMID:16101282;PMID:16487930;PMID:16892039;PMID:17142315;PMID:17616662;PMID:17786322;PMID:17889431;PMID:18036568;PMID:18065762;PMID:18223214;PMID:18546292;PMID:18620091;PMID:7848919;PMID:8382358;PMID:8383326;PMID:8386825;PMID:8386827;PMID:8522190 -2.7.10.1 * mus musculus 150000.0 12 PMID:1280821;PMID:16487930;PMID:1653651;PMID:16892039;PMID:17616662;PMID:18620091;PMID:20122929;PMID:2456920;PMID:7848919;PMID:8183555;PMID:8217221;PMID:8382358;PMID:8386827;PMID:8622893;PMID:8892754 -2.7.10.1 * rattus norvegicus 180000.0 2 PMID:16892039;PMID:8383326;PMID:8522190 -2.7.10.1 * sus scrofa 145000.0 1 PMID:1653651;PMID:8217221 -2.7.10.2 * avian sarcoma virus 61113.0 1 PMID:2983097 -2.7.10.2 * bos taurus 31000.0 1 PMID:17926339 -2.7.10.2 * canis lupus familiaris 60368.0 1 PMID:8588097 -2.7.10.2 * danio rerio 62000.0 1 PMID:15572145 -2.7.10.2 * drosophila melanogaster 130000.0 2 PMID:16456223;PMID:8423783 -2.7.10.2 * escherichia coli k-12 81000.0 1 PMID:16814990 -2.7.10.2 * gallus gallus 60911.0 1 PMID:2464785 -2.7.10.2 * homo sapiens 130000.0 21 PMID:12767803;PMID:1423621;PMID:1508179;PMID:15923611;PMID:16456223;PMID:17977941;PMID:18390748;PMID:1848670;PMID:18586953;PMID:18817770;PMID:20052711;PMID:2179816;PMID:2436037;PMID:24368807;PMID:2725517;PMID:7696183;PMID:7822795;PMID:7934162;PMID:8022790 -2.7.10.2 * mus musculus 130000.0 8 PMID:16148119;PMID:16456223;PMID:17918263;PMID:17977941;PMID:18775507;PMID:7477352;PMID:7551544;PMID:8437854 -2.7.10.2 * rattus norvegicus 125000.0 3 PMID:17918263;PMID:18584337 -2.7.10.2 * sus scrofa 32000.0 1 PMID:12493715 -2.7.10.2 * xenopus laevis 60000.0 2 PMID:2499582;PMID:2987836 -2.7.10.3 * burkholderia cepacia 59100.0 1 PMID:34439861 -2.7.10.4 * rattus norvegicus 100000.0 1 PMID:11884384 -2.7.11.1 * aquifex aeolicus 34000.0 1 PMID:18270660 -2.7.11.1 * arabidopsis thaliana 105000.0 5 PMID:7912697;PMID:7916621;PMID:7923358;PMID:8393717 -2.7.11.1 * archaeoglobus fulgidus 30100.0 1 PMID:22629386 -2.7.11.1 * autographa californica nucleopolyhedrovirus 32000.0 1 PMID:18353480 -2.7.11.1 * bifidobacterium longum 80070.0 10 PMID:26567574 -2.7.11.1 * bos taurus 45000.0 3 PMID:1322115;PMID:2154209;PMID:2539382;PMID:2835010 -2.7.11.1 * caenorhabditis elegans 42000.0 2 PMID:2318883 -2.7.11.1 * drosophila melanogaster 39833.0 2 PMID:3119988 -2.7.11.1 * gallus gallus 73132.0 1 PMID:3285296 -2.7.11.1 * glycine max 57175.0 1 PMID:1852075 -2.7.11.1 * homo sapiens 204000.0 9 PMID:17321610;PMID:19076219;PMID:26742424;PMID:7797465;PMID:8076686;PMID:9119030;PMID:9405610 -2.7.11.1 * listeria monocytogenes 72000.0 1 PMID:21406257 -2.7.11.1 * mus musculus 35000.0 1 PMID:26940607 -2.7.11.1 * mycobacterium tuberculosis 97000.0 6 PMID:15043876;PMID:15177288;PMID:18175374;PMID:8076686;PMID:9119030 -2.7.11.1 * mycolicibacterium smegmatis 56000.0 1 PMID:18031532 -2.7.11.1 * nicotiana tabacum 39500.0 2 * -2.7.11.1 * orthopoxvirus vaccinia 34000.0 1 PMID:2600076 -2.7.11.1 * rattus norvegicus 59109.0 7 PMID:1699226;PMID:1699810;PMID:7759525;PMID:8454611;PMID:8455596 -2.7.11.1 * saccharolobus solfataricus 125000.0 5 PMID:10852877;PMID:11976289;PMID:14702316 -2.7.11.1 * saccharomyces cerevisiae 126983.0 8 PMID:1625574;PMID:1627830;PMID:2125693;PMID:23166297;PMID:238628;PMID:8112585;PMID:8421676 -2.7.11.1 * schizosaccharomyces pombe 58370.0 2 PMID:3830131;PMID:7621824 -2.7.11.1 * staphylococcus aureus 75000.0 1 PMID:19376851 -2.7.11.1 * streptococcus pneumoniae 202000.0 1 PMID:17307148 -2.7.11.1 * streptomyces coelicolor 80000.0 3 PMID:18323658;PMID:25560431 -2.7.11.1 * sus scrofa 81000.0 1 PMID:215221 -2.7.11.1 * toxoplasma gondii 121000.0 1 PMID:27444499 -2.7.11.1 * zea mays 62000.0 1 PMID:14717609 -2.7.11.10 * homo sapiens 700000.0 1 PMID:19591457 -2.7.11.11 * amblyomma hebraeum 52500.0 3 PMID:17049629 -2.7.11.11 * homo sapiens 41000.0 1 PMID:15039079 -2.7.11.11 * komagataella pastoris 50000.0 1 PMID:14739998 -2.7.11.11 * manduca sexta 45100.0 1 PMID:15544940 -2.7.11.11 * mus musculus 42000.0 2 PMID:12614615;PMID:15039079 -2.7.11.11 * mytilus galloprovincialis 54000.0 10 PMID:12859988;PMID:16579959;PMID:18671732 -2.7.11.11 * plasmodium falciparum 50800.0 4 PMID:20663247 -2.7.11.11 * rattus norvegicus 121000.0 3 PMID:16996504 -2.7.11.11 * sus scrofa 55000.0 1 PMID:26983367 -2.7.11.11 * toxoplasma gondii 69000.0 1 PMID:21799871 -2.7.11.11 * trypanosoma equiperdum 57000.0 1 PMID:26983367 -2.7.11.11 * yarrowia lipolytica 90000.0 5 PMID:21382337 -2.7.11.12 * bos taurus 76331.0 4 PMID:17403045;PMID:19369251;PMID:19717728;PMID:6091741 -2.7.11.12 * drosophila melanogaster 84000.0 2 PMID:15218025 -2.7.11.12 * eimeria tenella 125000.0 1 PMID:15769621 -2.7.11.12 * homo sapiens 180000.0 9 PMID:12933804;PMID:16407222;PMID:18194177;PMID:19717728;PMID:2792381 -2.7.11.12 * mus musculus 77000.0 1 PMID:19717728 -2.7.11.12 * plasmodium falciparum 98000.0 1 PMID:16325279 -2.7.11.12 * rattus norvegicus 77000.0 1 PMID:19717728 -2.7.11.12 * sus scrofa 75000.0 1 PMID:17377806 -2.7.11.13 * choristoneura fumiferana 76000.0 1 PMID:18790718 -2.7.11.13 * homo sapiens 120000.0 4 PMID:11062248;PMID:8135837;PMID:8226978 -2.7.11.13 * mus musculus 100000.0 4 PMID:16740968;PMID:17653823;PMID:23289588 -2.7.11.13 * rattus norvegicus 116000.0 4 PMID:16740968;PMID:21215369;PMID:2470089;PMID:8051089 -2.7.11.13 * trichoderma reesei 126000.0 1 PMID:8569684 -2.7.11.14 * bos taurus 70000.0 16 PMID:1527025;PMID:1656454;PMID:2303419;PMID:2844754;PMID:3022791;PMID:690139;PMID:7115672;PMID:7629115;PMID:8634260;PMID:9380677;PMID:9665733 -2.7.11.14 * enteroctopus dofleini 80000.0 1 PMID:9516442 -2.7.11.14 * homo sapiens 63500.0 3 PMID:15946941;PMID:9934538 -2.7.11.15 * bos taurus 80000.0 5 PMID:12777817;PMID:2552582;PMID:3036840;PMID:7673171;PMID:8917529;PMID:9199496;PMID:9349395 -2.7.11.15 * homo sapiens 80000.0 1 PMID:17084806 -2.7.11.15 * mammalia 80000.0 1 PMID:17084806 -2.7.11.15 * mesocricetus auratus 80000.0 2 PMID:7673171;PMID:8917529;PMID:9199496;PMID:9349395 -2.7.11.15 * mus musculus 80000.0 1 PMID:7673171;PMID:8917529;PMID:9199496;PMID:9349395 -2.7.11.15 * rattus norvegicus 82000.0 8 PMID:1403099;PMID:17573483;PMID:7673171;PMID:8917529;PMID:9199496;PMID:9349395 -2.7.11.16 * homo sapiens 69000.0 2 PMID:16613860;PMID:17084806 -2.7.11.16 * mammalia 69000.0 1 PMID:17084806 -2.7.11.17 * aplysia californica 60000.0 2 PMID:4074698 -2.7.11.17 * aspergillus nidulans 46895.0 1 PMID:1563634 -2.7.11.17 * badhamia polycephala 42519.0 1 PMID:15707955 -2.7.11.17 * bos taurus 60000.0 3 PMID:1587865;PMID:3121601 -2.7.11.17 * candida albicans 71000.0 2 PMID:14577592 -2.7.11.17 * danio rerio 40620.0 1 PMID:20190269 -2.7.11.17 * funaria hygrometrica 70000.0 1 PMID:12711815 -2.7.11.17 * gallus gallus 141000.0 4 PMID:18079114;PMID:2176896;PMID:2998332;PMID:3415667;PMID:6150036 -2.7.11.17 * homo sapiens 550000.0 5 PMID:18454172;PMID:7641687;PMID:8089075 -2.7.11.17 * mammalia 60000.0 2 PMID:18703025 -2.7.11.17 * medicago sativa 60200.0 1 PMID:11283165 -2.7.11.17 * ovis aries 140000.0 1 PMID:8224219 -2.7.11.17 * rattus norvegicus 580000.0 21 PMID:12753081;PMID:16079472;PMID:17267544;PMID:1846291;PMID:18710651;PMID:2538431;PMID:2551690;PMID:2846534;PMID:2914893;PMID:3121601;PMID:4074698;PMID:7642608;PMID:7948038 -2.7.11.17 * xenopus laevis 45000.0 4 * -2.7.11.17 * xenopus sp. 42000.0 1 PMID:2842685 -2.7.11.18 * bos taurus 214000.0 9 PMID:1284247;PMID:1748666;PMID:18053800;PMID:3426560;PMID:3553171;PMID:3754106;PMID:500701;PMID:6934518;PMID:9806741 -2.7.11.18 * dictyostelium discoideum 34000.0 1 PMID:2380188 -2.7.11.18 * drosophila melanogaster 926000.0 1 PMID:10891286 -2.7.11.18 * gallus gallus 210000.0 3 PMID:15265689;PMID:26567572;PMID:3553171 -2.7.11.18 * homo sapiens 215000.0 11 PMID:12532105;PMID:14741352;PMID:15106625;PMID:15350530;PMID:156362;PMID:18435720;PMID:32770194;PMID:9160829 -2.7.11.18 * limulus sp. 39000.0 2 PMID:6549261 -2.7.11.18 * meleagris gallopavo 130000.0 3 PMID:6894756;PMID:6897613 -2.7.11.18 * mus musculus 210000.0 5 PMID:15106625;PMID:19403597;PMID:26512720 -2.7.11.18 * oryctolagus cuniculus 152000.0 7 PMID:15350530;PMID:1748666;PMID:4853304;PMID:588245;PMID:6547715 -2.7.11.18 * rattus norvegicus 220000.0 4 PMID:1748666;PMID:25483583;PMID:2730565 -2.7.11.18 * sus scrofa 130000.0 1 PMID:6311271 -2.7.11.19 * bos taurus 1300000.0 10 PMID:6301372;PMID:6777382 -2.7.11.19 * gallus gallus 1320000.0 1 PMID:3089780 -2.7.11.19 * homo sapiens 125000.0 1 PMID:25051373 -2.7.11.19 * mus musculus 138400.0 4 PMID:18549242 -2.7.11.19 * oryctolagus cuniculus 1330000.0 48 PMID:18281724;PMID:18549242;PMID:18794211;PMID:19141288;PMID:2189756;PMID:227235;PMID:228937;PMID:22964223;PMID:26551836;PMID:27845042;PMID:29098725;PMID:29098736;PMID:447740;PMID:4734893;PMID:6417451;PMID:6541504;PMID:6645971;PMID:6725254;PMID:6766459;PMID:6802824;PMID:6809757;PMID:7317377 -2.7.11.19 * rattus norvegicus 1300000.0 2 PMID:228937;PMID:6809757;PMID:7132965 -2.7.11.19 * saccharomyces cerevisiae 29000.0 1 PMID:6309169 -2.7.11.19 * squalus acanthias 1300000.0 1 PMID:7317377 -2.7.11.2 * arabidopsis thaliana 86000.0 2 PMID:10861228 -2.7.11.2 * ascaris suum 80000.0 1 PMID:9578613 -2.7.11.2 * bos taurus 100000.0 3 PMID:3004826;PMID:6348044;PMID:6358789 -2.7.11.2 * brassica napus 42000.0 1 PMID:21461604 -2.7.11.2 * caenorhabditis elegans 76000.0 2 * -2.7.11.2 * homo sapiens 90220.0 9 PMID:10748134;PMID:11642366;PMID:12816949;PMID:8798399 -2.7.11.2 * rattus norvegicus 92000.0 5 PMID:12573248;PMID:1644204;PMID:8253790 -2.7.11.2 * sus scrofa 136000.0 2 PMID:19051057;PMID:3840997 -2.7.11.20 * homo sapiens 160000.0 5 PMID:19636416;PMID:21605678 -2.7.11.20 * rattus norvegicus 81499.0 1 PMID:8663182 -2.7.11.21 * danio rerio 35930.0 3 PMID:18678933;PMID:18703838 -2.7.11.21 * homo sapiens 70000.0 8 PMID:14980500;PMID:16582488;PMID:18703838;PMID:19546225;PMID:19912216;PMID:20100802;PMID:25511705 -2.7.11.21 * mus musculus 72000.0 2 PMID:17342725;PMID:20100802 -2.7.11.21 * schistosoma mansoni 70500.0 1 PMID:20350550 -2.7.11.22 * aspergillus nidulans 34000.0 1 PMID:14668368 -2.7.11.22 * bos taurus 450000.0 5 PMID:1464604;PMID:16519508;PMID:8163203 -2.7.11.22 * candida albicans 58320.0 1 PMID:7891715 -2.7.11.22 * carassius auratus 34000.0 1 PMID:1339336;PMID:2132958;PMID:8221695 -2.7.11.22 * drosophila melanogaster 32000.0 1 PMID:7805863 -2.7.11.22 * homo sapiens 110000.0 6 PMID:1339336;PMID:14642819;PMID:15963510;PMID:17517622;PMID:2132958;PMID:8170997;PMID:8221695 -2.7.11.22 * mus musculus 40000.0 3 PMID:1339336;PMID:16552187;PMID:19513615;PMID:2132958;PMID:8221695 -2.7.11.22 * ostreococcus tauri 37000.0 1 PMID:15965018 -2.7.11.22 * saccharomyces cerevisiae 35000.0 1 PMID:24022486 -2.7.11.22 * trypanosoma brucei 86000.0 1 PMID:23805309 -2.7.11.23 * homo sapiens 340000.0 4 PMID:8486698 -2.7.11.23 * saccharomyces cerevisiae 120000.0 4 PMID:2657724 -2.7.11.23 * triticum aestivum 200000.0 1 PMID:2535525 -2.7.11.24 * echinococcus multilocularis 42000.0 1 PMID:16793045 -2.7.11.24 * fusarium solani 41194.0 1 PMID:9305760 -2.7.11.24 * homo sapiens 45000.0 1 PMID:20045647 -2.7.11.24 * medicago sativa 46000.0 3 PMID:15448198;PMID:8439746 -2.7.11.24 * mus musculus 64000.0 1 PMID:15294293 -2.7.11.24 * petunia x hybrida 44400.0 1 PMID:7888623 -2.7.11.24 * rattus norvegicus 100000.0 5 PMID:15269285;PMID:16028365;PMID:1846291;PMID:20130174 -2.7.11.24 * schizosaccharomyces pombe 45000.0 1 PMID:1899230 -2.7.11.24 * zea mays 45000.0 1 PMID:19424717 -2.7.11.25 * homo sapiens 600000.0 3 PMID:16087150 -2.7.11.25 * mus musculus 180000.0 1 PMID:9079650;PMID:9693384 -2.7.11.25 * schizosaccharomyces pombe 180000.0 1 PMID:9079650;PMID:9693384 -2.7.11.25 * solanum chacoense 36200.0 3 PMID:17110585;PMID:25576576 -2.7.11.25 * synthetic construct 195000.0 1 PMID:16472679 -2.7.11.26 * bombyx mori 47000.0 1 PMID:19111579;PMID:19418600;PMID:19445946;PMID:19493954;PMID:19714564 -2.7.11.26 * bos taurus 45000.0 3 PMID:1587865;PMID:7556643;PMID:9089387 -2.7.11.26 * homo sapiens 230000.0 13 PMID:10818091;PMID:1587865;PMID:16923168;PMID:17620722;PMID:18070606;PMID:19111579;PMID:19418600;PMID:19445946;PMID:19493954;PMID:19714564;PMID:7786411;PMID:9089387 -2.7.11.26 * leishmania donovani 47000.0 1 PMID:19111579;PMID:19418600;PMID:19445946;PMID:19493954;PMID:19714564 -2.7.11.26 * mus musculus 100000.0 3 PMID:11257498;PMID:16923168;PMID:19111579;PMID:19418600;PMID:19445946;PMID:19493954;PMID:19714564 -2.7.11.26 * rattus norvegicus 47000.0 2 PMID:19111579;PMID:19418600;PMID:19445946;PMID:19493954;PMID:19714564;PMID:2467901 -2.7.11.28 * gallus gallus 252000.0 1 PMID:3593768 -2.7.11.29 * bos taurus 170000.0 2 PMID:3597414 -2.7.11.3 * rattus norvegicus 380000.0 3 PMID:291971;PMID:8910387 -2.7.11.30 * glycine soja 93220.0 1 PMID:23276523 -2.7.11.30 * homo sapiens 65000.0 1 PMID:19366699 -2.7.11.31 * brassica oleracea 200000.0 5 PMID:8112324 -2.7.11.31 * homo sapiens 155000.0 4 PMID:20451617;PMID:26489410 -2.7.11.31 * magallana gigas 60000.0 1 PMID:23926284 -2.7.11.31 * rattus norvegicus 600000.0 28 PMID:12764152;PMID:16026327;PMID:291971;PMID:3308873;PMID:6111317;PMID:6120170;PMID:6146523;PMID:6698994;PMID:6712234;PMID:7672204;PMID:7907095;PMID:8626596;PMID:8910387;PMID:9475166 -2.7.11.32 * zea mays 180000.0 4 PMID:16696949;PMID:2983615 -2.7.11.33 * escherichia coli 25000.0 1 PMID:20044937 -2.7.11.35 * drosophila melanogaster 211000.0 1 PMID:15371536 -2.7.11.35 * homo sapiens 183000.0 1 PMID:27453578 -2.7.11.35 * mus musculus 240000.0 1 PMID:9792683 -2.7.11.39 * homo sapiens 175000.0 2 PMID:11018042;PMID:12102637 -2.7.11.4 * bos taurus 43000.0 1 PMID:1910451 -2.7.11.4 * oryctolagus cuniculus 2000000.0 2 PMID:2853818;PMID:3004826;PMID:7142221 -2.7.11.4 * rattus norvegicus 45000.0 3 PMID:10989428;PMID:1377677;PMID:2177326 -2.7.11.5 * escherichia coli 135000.0 7 PMID:10231385;PMID:11258918;PMID:20505668;PMID:27528271;PMID:6329756;PMID:8620880 -2.7.11.7 * acanthamoeba castellanii 107000.0 4 PMID:1851936;PMID:6309772;PMID:9892644 -2.7.11.7 * bos taurus 160000.0 1 PMID:6327658 -2.7.11.7 * dictyostelium discoideum 700000.0 9 PMID:12475956;PMID:18504297;PMID:1851940;PMID:20197546;PMID:2549052;PMID:3027076 -2.7.11.7 * gallus gallus 490000.0 2 PMID:2822719 -2.7.11.8 * mus musculus 60000.0 4 PMID:25704814 -2.7.12.1 * arachis hypogaea 55000.0 1 PMID:15379551 -2.7.12.1 * mus musculus 75000.0 3 PMID:12633499 -2.7.12.1 * rattus norvegicus 90000.0 1 PMID:19722700 -2.7.12.2 * gossypium hirsutum 57523.0 1 PMID:27335349 -2.7.12.2 * homo sapiens 47940.0 7 PMID:1281467;PMID:16442502;PMID:22828509;PMID:8663074 -2.7.12.2 * leishmania mexicana 39000.0 2 PMID:15882412 -2.7.12.2 * mus musculus 93000.0 8 PMID:17377140;PMID:8297798;PMID:8621389 -2.7.12.2 * oryctolagus cuniculus 43330.0 2 PMID:1461659;PMID:1499729 -2.7.12.2 * rattus norvegicus 195000.0 4 PMID:7592896;PMID:8462694;PMID:8643568 -2.7.12.2 * saccharomyces cerevisiae 77500.0 1 PMID:3039511 -2.7.12.2 * schizosaccharomyces pombe 66000.0 1 PMID:1756736 -2.7.12.2 * xenopus laevis 45000.0 1 PMID:8440264 -2.7.13.1 * escherichia coli 36000.0 1 PMID:8132603 -2.7.13.1 * rattus norvegicus 70000.0 1 PMID:8132640 -2.7.13.1 * saccharomyces cerevisiae 32000.0 1 PMID:2026610 -2.7.13.3 * alternaria brassicicola 130000.0 1 PMID:19011080 -2.7.13.3 * anaplasma phagocytophilum 50000.0 1 PMID:18978058 -2.7.13.3 * arabidopsis thaliana 111000.0 2 PMID:32121559;PMID:7759498 -2.7.13.3 * bacillus anthracis 88000.0 2 PMID:18931112 -2.7.13.3 * bacillus subtilis 99000.0 6 PMID:1938941;PMID:20035725;PMID:2509430;PMID:8002615;PMID:8439156;PMID:8497199 -2.7.13.3 * brevibacillus brevis 43800.0 1 PMID:7765823 -2.7.13.3 * corynebacterium glutamicum 54000.0 1 PMID:17650500 -2.7.13.3 * escherichia coli 102452.0 9 PMID:1532388;PMID:1574005;PMID:1729240;PMID:19748340;PMID:2657652;PMID:2835585;PMID:2997120;PMID:3058985;PMID:3550103 -2.7.13.3 * klebsiella pneumoniae 38409.0 1 PMID:2999699 -2.7.13.3 * myxococcus xanthus 83000.0 2 PMID:18390653;PMID:2165608 -2.7.13.3 * pseudomonas aeruginosa 66000.0 2 PMID:8361354;PMID:9218420 -2.7.13.3 * salmonella enterica subsp. enterica serovar typhimurium 73000.0 1 PMID:3278311 -2.7.13.3 * streptococcus mutans serotype c 103200.0 1 PMID:23468592 -2.7.13.3 * synechococcus sp. 46389.0 1 PMID:8497200 -2.7.13.3 * synechocystis sp. 74500.0 1 * -2.7.13.3 * synechocystis sp. pcc 6803 250000.0 3 PMID:29290041 -2.7.13.3 * thermotoga maritima 76000.0 2 PMID:16890956 -2.7.13.3 * vibrio cholerae o1 133000.0 1 PMID:27670078 -2.7.13.3 * vibrio parahaemolyticus 75000.0 1 PMID:19748340 -2.7.13.3 * xanthomonas oryzae pv. oryzae 48900.0 2 PMID:20507481 -2.7.2.1 * acetivibrio thermocellus 84000.0 2 * -2.7.2.1 * acholeplasma laidlawii 130000.0 5 PMID:217865 -2.7.2.1 * clostridium acetobutylicum 94000.0 5 PMID:30411;PMID:9082921 -2.7.2.1 * escherichia coli 86000.0 5 PMID:24801996;PMID:3020034 -2.7.2.1 * ethanoligenens harbinense 43220.0 1 PMID:17619101 -2.7.2.1 * fructilactobacillus sanfranciscensis 57000.0 2 PMID:11716215 -2.7.2.1 * geobacillus stearothermophilus 170000.0 4 PMID:29037 -2.7.2.1 * methanosarcina mazei 45000.0 2 PMID:12402077 -2.7.2.1 * methanosarcina thermophila 94000.0 5 PMID:2844814 -2.7.2.1 * methylotuvimicrobium alcaliphilum 80000.0 2 PMID:26275877 -2.7.2.1 * neomoorella thermoacetica 60000.0 1 PMID:4447427 -2.7.2.1 * nitratidesulfovibrio vulgaris 76400.0 4 PMID:11226881 -2.7.2.1 * porphyromonas gingivalis 108000.0 1 PMID:31007866 -2.7.2.1 * propionibacterium freudenreichii 240000.0 2 * -2.7.2.1 * rhodopseudomonas palustris 48000.0 4 PMID:3024667 -2.7.2.1 * salmonella enterica subsp. enterica serovar typhimurium 68000.0 3 PMID:23031654;PMID:3020034 -2.7.2.1 * shewanella sp. 86000.0 3 PMID:24801996 -2.7.2.1 * spirochaeta sp. 125000.0 2 PMID:6288660 -2.7.2.1 * thermotoga maritima 90000.0 2 PMID:10074080 -2.7.2.1 * veillonella parvula 88000.0 6 PMID:178662;PMID:216674;PMID:30411 -2.7.2.11 * chlamydomonas reinhardtii 100000.0 1 PMID:21444242 -2.7.2.11 * escherichia coli 236000.0 2 PMID:6319365 -2.7.2.11 * leishmania donovani 105000.0 1 PMID:29777624 -2.7.2.11 * meiothermus ruber 41984.0 1 * -2.7.2.11 * pseudomonas aeruginosa 84000.0 1 PMID:226082 -2.7.2.11 * saccharomyces cerevisiae 47000.0 1 PMID:17449694 -2.7.2.11 * thermotoga maritima 42000.0 1 PMID:20544237 -2.7.2.11 * triticum aestivum 254000.0 3 * -2.7.2.12 * entamoeba histolytica 77000.0 3 PMID:24856051;PMID:26922831 -2.7.2.14 * spirochaeta sp. 76000.0 1 PMID:6288660 -2.7.2.14 * thermotoga maritima 380000.0 2 PMID:12777787 -2.7.2.15 * escherichia coli 43340.0 1 PMID:9484901 -2.7.2.15 * salmonella enterica subsp. enterica serovar typhimurium 44000.0 1 PMID:16139298 -2.7.2.16 * methanothermus fervidus 1400000.0 1 PMID:2226838 -2.7.2.18 * staphylococcus aureus 240000.0 1 PMID:25002480 -2.7.2.2 * enterococcus faecalis 66000.0 3 * -2.7.2.2 * enterococcus faecium 328000.0 2 PMID:9578487 -2.7.2.2 * lentilactobacillus buchneri 97000.0 1 PMID:3030360 -2.7.2.2 * metamycoplasma hominis 61000.0 1 * -2.7.2.2 * pseudomonas aeruginosa 74000.0 2 PMID:6286599 -2.7.2.2 * pyrococcus furiosus 34000.0 1 PMID:10347186 -2.7.2.2 * streptococcus pyogenes 34200.0 1 PMID:23867361 -2.7.2.2 * trichomonas vaginalis 70000.0 2 PMID:10864518 -2.7.2.3 * abramis brama 48000.0 1 PMID:367367 -2.7.2.3 * beta vulgaris 48000.0 2 PMID:1261557;PMID:22905379;PMID:367367 -2.7.2.3 * bos taurus 49500.0 4 PMID:10585490;PMID:1175587;PMID:367367;PMID:6489338 -2.7.2.3 * bufo vulgaris 48000.0 1 PMID:367367 -2.7.2.3 * chlamydomonas reinhardtii 45000.0 1 PMID:25202015 -2.7.2.3 * chrysophrys guttulatus 48000.0 1 PMID:367367 -2.7.2.3 * clonorchis sinensis 45000.0 1 PMID:10838223;PMID:15158737 -2.7.2.3 * columba sp. 48000.0 1 PMID:367367 -2.7.2.3 * corynebacterium glutamicum 104000.0 3 PMID:24593686;PMID:33234025 -2.7.2.3 * cyprinus carpio 48000.0 1 PMID:367367 -2.7.2.3 * dromaius novaehollandiae 48000.0 1 PMID:367367 -2.7.2.3 * equus caballus 48000.0 4 PMID:367367 -2.7.2.3 * escherichia coli 43700.0 1 * -2.7.2.3 * fasciola hepatica 47900.0 1 PMID:7242569 -2.7.2.3 * gallus gallus 48000.0 1 PMID:367367 -2.7.2.3 * geobacillus stearothermophilus 42000.0 1 * -2.7.2.3 * helianthus annuus 45000.0 3 PMID:22552275 -2.7.2.3 * hippoglossus stenolepis 43500.0 1 PMID:6982068 -2.7.2.3 * homo sapiens 50000.0 9 PMID:1112804;PMID:16493704;PMID:182276;PMID:5009693;PMID:5009694 -2.7.2.3 * hordeum vulgare 38000.0 1 PMID:16667476 -2.7.2.3 * lactobacillus delbrueckii subsp. lactis 46000.0 2 PMID:21816671;PMID:23844 -2.7.2.3 * macropus fuliginosus 48000.0 1 PMID:367367 -2.7.2.3 * macropus giganteus 48000.0 1 PMID:367367 -2.7.2.3 * methanobacterium bryantii 44800.0 2 PMID:7588750 -2.7.2.3 * methanothermus fervidus 97100.0 9 PMID:7588750 -2.7.2.3 * monoraphidium minutum 44000.0 1 * -2.7.2.3 * mus musculus 47000.0 5 PMID:1261557;PMID:21816671;PMID:22905379;PMID:23844 -2.7.2.3 * nicotiana benthamiana 50000.0 3 PMID:17169994;PMID:24154620;PMID:4598740 -2.7.2.3 * nitrobacter winogradskyi 46100.0 1 * -2.7.2.3 * nitrosomonas europaea 44600.0 1 * -2.7.2.3 * nitrosomonas sp. k1 43700.0 1 * -2.7.2.3 * nitrosomonas sp. tno632 44300.0 1 * -2.7.2.3 * nitrosospira multiformis atcc 25196 45800.0 1 PMID:16233723 -2.7.2.3 * nitrosospira sp. gs833 44900.0 1 PMID:16233723 -2.7.2.3 * nitrosospira sp. kan8 44700.0 1 PMID:16233723 -2.7.2.3 * nitrosospira sp. nrs527 45200.0 1 PMID:16233723 -2.7.2.3 * nitrosospira sp. pja1 45700.0 1 PMID:16233723 -2.7.2.3 * nitrosospira sp. tch716 45800.0 1 PMID:16233723 -2.7.2.3 * nitrosospira sp. tym9 44400.0 1 PMID:16233723 -2.7.2.3 * nitrosovibrio sp. fji423 44200.0 1 PMID:16233723 -2.7.2.3 * nitrosovibrio sp. fji82 43900.0 1 PMID:16233723 -2.7.2.3 * nitrosovibrio sp. ry3c 44700.0 1 PMID:16233723 -2.7.2.3 * nitrosovibrio sp. ry6a 44900.0 1 PMID:16233723 -2.7.2.3 * oncorhynchus mykiss 48000.0 1 PMID:367367 -2.7.2.3 * oryctolagus cuniculus 48000.0 3 PMID:367367 -2.7.2.3 * oryza sativa 42100.0 1 PMID:26408146 -2.7.2.3 * ovis aries 47000.0 1 PMID:639826 -2.7.2.3 * phaeodactylum tricornutum 45000.0 1 PMID:21816671;PMID:23844 -2.7.2.3 * plasmodium falciparum 48000.0 2 PMID:10838223;PMID:15158737;PMID:1639156 -2.7.2.3 * pseudocheirus peregrinus 48000.0 1 PMID:367367 -2.7.2.3 * pseudomonas sp. 40000.0 1 PMID:10753921 -2.7.2.3 * pyrococcus woesei 102700.0 10 PMID:7588750 -2.7.2.3 * rattus norvegicus 48000.0 2 PMID:24154620;PMID:367367;PMID:4598740 -2.7.2.3 * rhodopseudomonas palustris 43400.0 1 * -2.7.2.3 * saccharolobus solfataricus 44395.0 2 PMID:8521845 -2.7.2.3 * saccharomyces cerevisiae 50000.0 4 PMID:10585490;PMID:367367;PMID:6489338 -2.7.2.3 * salmo trutta 48000.0 1 PMID:367367 -2.7.2.3 * schistosoma japonicum 47000.0 2 PMID:24858924;PMID:26299245 -2.7.2.3 * spinacia oleracea 48000.0 5 PMID:10585490;PMID:16667463;PMID:367367;PMID:6489338 -2.7.2.3 * spirulina geitleri 46000.0 1 PMID:10585490;PMID:6489338 -2.7.2.3 * sus scrofa 48000.0 2 PMID:367367 -2.7.2.3 * thermoanaerobacter sp. 42000.0 1 * -2.7.2.3 * thermus thermophilus 44600.0 3 PMID:457645 -2.7.2.3 * thylogale billardierii 48000.0 1 PMID:367367 -2.7.2.3 * trichosurus vulpecula 48000.0 1 PMID:367367 -2.7.2.3 * trypanosoma brucei 180000.0 4 PMID:10585490;PMID:6489338;PMID:9521762;PMID:9675273 -2.7.2.3 * trypanosoma cruzi 57000.0 3 PMID:24858924;PMID:26299245 -2.7.2.3 * trypanosoma rangeli 44000.0 2 PMID:3026343;PMID:33234025 -2.7.2.3 * vombatus sp. 48000.0 1 * -2.7.2.3 * zymomonas mobilis 44000.0 1 PMID:3026343;PMID:33234025 -2.7.2.4 * amycolatopsis lactamdurans 44108.0 2 PMID:11390685 -2.7.2.4 * arabidopsis thaliana 470000.0 9 PMID:11812230;PMID:12435751;PMID:17140415 -2.7.2.4 * bacillus subtilis 250000.0 17 PMID:11471740;PMID:15033471;PMID:194888 -2.7.2.4 * brevibacillus brevis 110000.0 2 PMID:182279 -2.7.2.4 * clostridium acetobutylicum 48030.0 1 PMID:25170437 -2.7.2.4 * corynebacterium flavescens 45000.0 2 PMID:7766138 -2.7.2.4 * corynebacterium glutamicum 42000.0 7 PMID:17350037 -2.7.2.4 * corynebacterium pekinense 130000.0 3 PMID:26633359 -2.7.2.4 * daucus carota 258000.0 6 * -2.7.2.4 * escherichia coli 360000.0 19 PMID:4370136;PMID:4551091;PMID:4562990;PMID:8914836 -2.7.2.4 * geobacillus stearothermophilus 110000.0 1 * -2.7.2.4 * methanocaldococcus jannaschii 154000.0 3 PMID:17012784 -2.7.2.4 * paenibacillus polymyxa 116000.0 5 PMID:4697398 -2.7.2.4 * pseudomonas fluorescens 137000.0 3 PMID:4357740 -2.7.2.4 * pseudomonas putida 126000.0 1 * -2.7.2.4 * rhodocyclus tenuis 100000.0 1 * -2.7.2.4 * saccharomyces cerevisiae 346000.0 10 PMID:15358146 -2.7.2.4 * sorghum bicolor 167000.0 2 * -2.7.2.4 * spinacia oleracea 330000.0 5 PMID:9584993 -2.7.2.4 * streptococcus mutans 242000.0 2 PMID:26656 -2.7.2.4 * streptomyces murayamaensis 160000.0 1 PMID:27485103 -2.7.2.4 * stutzerimonas stutzeri 52400.0 5 PMID:21725014 -2.7.2.4 * synechocystis sp. 140000.0 1 PMID:20398676 -2.7.2.4 * thermotoga maritima 450000.0 2 PMID:30175674 -2.7.2.4 * thermus thermophilus 122400.0 17 PMID:15033471;PMID:16232547;PMID:17277448;PMID:19490113 -2.7.2.4 * zea mays 255000.0 7 PMID:16667223;PMID:16667473 -2.7.2.7 * clostridium acetobutylicum 85000.0 5 PMID:10937485;PMID:3027059 -2.7.2.7 * nitratidesulfovibrio vulgaris 94700.0 1 PMID:32166312 -2.7.2.8 * arabidopsis thaliana 198000.0 3 PMID:16377628;PMID:16545809;PMID:19631611 -2.7.2.8 * chlamydomonas reinhardtii 400000.0 1 * -2.7.2.8 * corynebacterium glutamicum 36000.0 2 PMID:21901472;PMID:22101454 -2.7.2.8 * lathyrus oleraceus 190000.0 4 PMID:6272749 -2.7.2.8 * pseudomonas aeruginosa 230000.0 4 PMID:12037312;PMID:15342584;PMID:170089 -2.7.2.8 * saccharomyces cerevisiae 52000.0 1 PMID:11553611 -2.7.2.8 * synechococcus elongatus 180000.0 2 PMID:15502156 -2.7.2.8 * thermotoga maritima 180000.0 3 PMID:15342584 -2.7.3.1 * hediste diversicolor 80000.0 3 PMID:10071924 -2.7.3.1 * namalycastis sp. 40000.0 1 PMID:15694586 -2.7.3.1 * nephtys caeca 89150.0 4 PMID:5637051 -2.7.3.1 * perinereis sp. 90000.0 3 * -2.7.3.10 * ochromonas danica 80000.0 1 * -2.7.3.2 * bos taurus 85100.0 5 PMID:148914;PMID:15804623;PMID:435482 -2.7.3.2 * canis lupus familiaris 84000.0 2 PMID:30559651;PMID:6654916;PMID:6766941 -2.7.3.2 * chaetopterus variopedatus 347000.0 4 PMID:15975860 -2.7.3.2 * clupea harengus 345000.0 12 PMID:15763518;PMID:25770046 -2.7.3.2 * cryptosporidium muris 90000.0 1 PMID:32470517 -2.7.3.2 * cyprinus carpio 85100.0 1 PMID:5490232 -2.7.3.2 * eidolon helvum 80000.0 2 PMID:3780189 -2.7.3.2 * equus caballus 84500.0 3 PMID:7275956 -2.7.3.2 * gallus gallus 360000.0 13 PMID:15804623;PMID:2394753;PMID:2831887;PMID:3182823;PMID:3182824;PMID:3674368;PMID:6418727 -2.7.3.2 * homo sapiens 371000.0 17 PMID:11154064;PMID:15804623;PMID:20381520;PMID:28432439;PMID:28916380;PMID:29539608;PMID:3182823;PMID:6418727;PMID:6654916;PMID:6766941;PMID:9152853 -2.7.3.2 * mus musculus 100000.0 3 PMID:30559651;PMID:6766941;PMID:7150317 -2.7.3.2 * oryctolagus cuniculus 86000.0 5 PMID:12590573;PMID:15804623;PMID:22715856 -2.7.3.2 * rattus norvegicus 49000.0 1 PMID:6830587 -2.7.3.2 * strongylocentrotus purpuratus 240000.0 4 PMID:3680241 -2.7.3.2 * sus scrofa 82000.0 1 * -2.7.3.2 * urocitellus richardsonii 43000.0 1 PMID:17888865 -2.7.3.2 * xenopus laevis 42000.0 4 PMID:3242493 -2.7.3.3 * abyssogena kaikoi 82000.0 2 PMID:12127572;PMID:18639645;PMID:22016076 -2.7.3.3 * amphibalanus amphitrite 40000.0 1 PMID:27245369 -2.7.3.3 * amphioctopus fangsiao 38000.0 1 PMID:22303807 -2.7.3.3 * anthopleura japonica 80000.0 3 PMID:20434482;PMID:9359868 -2.7.3.3 * apis mellifera 36000.0 1 PMID:4689779 -2.7.3.3 * apostichopus japonicus 42000.0 1 PMID:17009952;PMID:2836197 -2.7.3.3 * ascaris suum 85000.0 2 PMID:21781373 -2.7.3.3 * bombyx mori 42000.0 1 PMID:19339797;PMID:32464434 -2.7.3.3 * cissites cephalotes 40000.0 1 PMID:16712519;PMID:17368197;PMID:17496423;PMID:17572125;PMID:19239924;PMID:19891510;PMID:30641133;PMID:33127981 -2.7.3.3 * corallium japonicum 40000.0 1 PMID:24055770;PMID:24726623;PMID:29022133 -2.7.3.3 * corallium rubrum 40000.0 1 PMID:24055770;PMID:24726623;PMID:29022133 -2.7.3.3 * corbicula japonica 80000.0 1 PMID:12127572;PMID:22016076 -2.7.3.3 * ctenocephalides felis 43400.0 2 PMID:19595766 -2.7.3.3 * daphnia magna 41000.0 1 PMID:32863281 -2.7.3.3 * drosophila melanogaster 40000.0 1 PMID:4359471;PMID:9281313 -2.7.3.3 * euphausia superba 40000.0 1 PMID:24690537 -2.7.3.3 * frankliniella occidentalis 40000.0 1 PMID:16712519;PMID:17368197;PMID:17496423;PMID:17572125;PMID:19239924;PMID:19891510;PMID:30641133;PMID:33127981 -2.7.3.3 * haemonchus contortus 46000.0 1 PMID:23583781 -2.7.3.3 * homarus americanus 40000.0 1 PMID:4962497 -2.7.3.3 * homarus gammarus 42000.0 2 PMID:4369044;PMID:5084802 -2.7.3.3 * isostychopus badonotus 40000.0 1 PMID:16712519;PMID:17368197;PMID:17496423;PMID:17572125;PMID:19239924;PMID:19891510;PMID:30641133;PMID:33127981 -2.7.3.3 * limulus polyphemus 40238.0 1 PMID:7819288 -2.7.3.3 * locusta migratoria manilensis 40000.0 2 PMID:16712519;PMID:17368197;PMID:17496423;PMID:17572125;PMID:19239924;PMID:19891510;PMID:21549198;PMID:22643639;PMID:30641133;PMID:33127981 -2.7.3.3 * lucilia cuprina 40000.0 1 PMID:21624495;PMID:23138227 -2.7.3.3 * macrobrachium rosenbergii 40000.0 1 PMID:21549198;PMID:22643639 -2.7.3.3 * manduca sexta 40000.0 1 PMID:193843 -2.7.3.3 * mizuhopecten yessoensis 83270.0 4 PMID:32092594 -2.7.3.3 * molpadia arenicola 80000.0 2 PMID:24726623 -2.7.3.3 * myzostoma cirriferum 39600.0 3 PMID:27095694 -2.7.3.3 * nautilus pompilius 40500.0 1 PMID:10811656 -2.7.3.3 * octopus vulgaris 40500.0 1 PMID:10811656 -2.7.3.3 * pandalus borealis 40000.0 1 PMID:16712519;PMID:17368197;PMID:17496423;PMID:17572125;PMID:19239924;PMID:19891510;PMID:30641133;PMID:33127981 -2.7.3.3 * paracentrotus lividus 81000.0 2 PMID:17009952;PMID:2836197 -2.7.3.3 * paramecium tetraurelia 42000.0 1 PMID:19339797;PMID:32464434 -2.7.3.3 * pecten maximus 42000.0 1 PMID:1764917 -2.7.3.3 * penaeus aztecus 40000.0 1 PMID:4359471;PMID:9281313 -2.7.3.3 * penaeus chinensis 80000.0 2 PMID:16616362 -2.7.3.3 * penaeus indicus 40000.0 1 PMID:16712519;PMID:17368197;PMID:17496423;PMID:17572125;PMID:19239924;PMID:19891510;PMID:30641133;PMID:33127981 -2.7.3.3 * penaeus japonicus 40000.0 1 PMID:21624495;PMID:23138227 -2.7.3.3 * penaeus merguiensis 40000.0 1 PMID:16712519;PMID:17368197;PMID:17496423;PMID:17572125;PMID:19239924;PMID:19891510;PMID:30641133;PMID:33127981 -2.7.3.3 * penaeus monodon 40000.0 1 PMID:16712519;PMID:17368197;PMID:17496423;PMID:17572125;PMID:19239924;PMID:19891510;PMID:30641133;PMID:33127981 -2.7.3.3 * penaeus notialis 40000.0 1 PMID:16712519;PMID:17368197;PMID:17496423;PMID:17572125;PMID:19239924;PMID:19891510;PMID:30641133;PMID:33127981 -2.7.3.3 * penaeus vannamei 40000.0 3 PMID:16712519;PMID:17368197;PMID:17496423;PMID:17572125;PMID:19239924;PMID:19891510;PMID:23873077;PMID:30641133;PMID:33127981 -2.7.3.3 * periplaneta americana 43000.0 2 PMID:15146540;PMID:16759988 -2.7.3.3 * phormia regina 37400.0 1 * -2.7.3.3 * phytomonas sp. 40000.0 1 PMID:21624495;PMID:23138227 -2.7.3.3 * pleoticus muelleri 40000.0 1 PMID:16712519;PMID:17368197;PMID:17496423;PMID:17572125;PMID:19239924;PMID:19891510;PMID:30641133;PMID:33127981 -2.7.3.3 * polybetes pythagoricus 43000.0 1 PMID:28924503 -2.7.3.3 * portunus trituberculatus 40500.0 2 PMID:10811656;PMID:21624495;PMID:23138227 -2.7.3.3 * procambarus clarkii 40000.0 1 PMID:24055770;PMID:24726623;PMID:29022133 -2.7.3.3 * sabella pavonina 150000.0 1 PMID:196847;PMID:5563365 -2.7.3.3 * sabellastarte spectabilis 80000.0 6 PMID:17294143 -2.7.3.3 * scylla serrata 40000.0 1 PMID:21432856 -2.7.3.3 * sepioteuthis lessoniana 40500.0 1 PMID:10811656 -2.7.3.3 * solen strictus 80000.0 1 PMID:12127572;PMID:22016076 -2.7.3.3 * sthenoteuthis oualaniensis 55000.0 1 PMID:15519 -2.7.3.3 * strongylocentrotus purpuratus 40000.0 1 PMID:16712519;PMID:17368197;PMID:17496423;PMID:17572125;PMID:19239924;PMID:19891510;PMID:30641133;PMID:33127981 -2.7.3.3 * teladorsagia circumcincta 46000.0 1 PMID:23583781 -2.7.3.3 * tetrahymena pyriformis 80000.0 2 PMID:24055770;PMID:24726623;PMID:29022133 -2.7.3.3 * toxocara canis 85000.0 3 PMID:17574244;PMID:22398835 -2.7.3.3 * tribolium castaneum 40000.0 2 PMID:16712519;PMID:17368197;PMID:17496423;PMID:17572125;PMID:19239924;PMID:19891510;PMID:30641133;PMID:33127981 -2.7.3.3 * trypanosoma brucei 45000.0 2 PMID:11908902;PMID:26218532 -2.7.3.3 * trypanosoma brucei brucei 55000.0 1 PMID:23776565 -2.7.3.3 * trypanosoma cruzi 40201.0 1 PMID:10625703 -2.7.3.4 * arenicola brasiliensis 46200.0 2 PMID:16008553 -2.7.3.4 * arenicola marina 80000.0 3 PMID:428380;PMID:5840960 -2.7.3.4 * clonorchis sinensis 80270.0 5 PMID:18765922;PMID:24278491 -2.7.3.4 * paragonimus westermani 80220.0 1 PMID:19500582 -2.7.3.4 * phytophthora infestans 80000.0 2 PMID:23499944 -2.7.3.4 * riftia pachyptila 40830.0 1 PMID:16188310 -2.7.3.4 * schistosoma mansoni 80000.0 1 PMID:18765922;PMID:24278491 -2.7.3.5 * lumbriculus variegatus 41437.0 1 PMID:20230902 -2.7.3.5 * lumbricus terrestris 80000.0 2 PMID:4371506;PMID:5840960 -2.7.3.5 * tubifex tubifex 41649.0 1 PMID:20230902 -2.7.3.5 * urechis caupo 40941.0 1 PMID:11866456 -2.7.3.9 * bacillus subtilis 130000.0 1 PMID:16716080 -2.7.3.9 * caldanaerobacter subterraneus subsp. tengcongensis 38165.0 1 PMID:21250658 -2.7.3.9 * cereibacter sphaeroides 160000.0 1 PMID:6277369 -2.7.3.9 * enterococcus faecalis 140000.0 2 PMID:3922407 -2.7.3.9 * escherichia coli 135000.0 6 PMID:22936614;PMID:23632921;PMID:2457575;PMID:28781960;PMID:2960675;PMID:6992959 -2.7.3.9 * mesomycoplasma hyopneumoniae 72000.0 1 PMID:10920262 -2.7.3.9 * mycoplasma capricolum 220000.0 6 PMID:330508;PMID:9188690 -2.7.3.9 * salmonella enterica subsp. enterica serovar typhimurium 150000.0 2 PMID:6754728 -2.7.3.9 * staphylococcus carnosus 63369.0 1 PMID:1551842 -2.7.3.9 * streptococcus pneumoniae 120100.0 1 PMID:26990554 -2.7.3.9 * streptococcus salivarius 135000.0 2 PMID:16716080;PMID:6673822 -2.7.3.9 * streptomyces coelicolor 28200.0 2 PMID:20630900 -2.7.3.9 * treponema denticola 70000.0 1 PMID:15641785 -2.7.4.1 * acinetobacter baylyi adp1 79000.0 1 PMID:10473375 -2.7.4.1 * corynebacterium glutamicum 151400.0 2 PMID:17545325;PMID:32885332 -2.7.4.1 * cupriavidus necator 79600.0 7 PMID:26407880 -2.7.4.1 * dictyostelium discoideum 720000.0 2 PMID:17940044 -2.7.4.1 * escherichia coli 275000.0 4 PMID:12767929;PMID:2164013 -2.7.4.1 * hydrogenophilaceae bacterium 44000.0 1 PMID:31907778 -2.7.4.1 * mycobacterium tuberculosis 197000.0 3 PMID:21179463;PMID:22110640 -2.7.4.1 * mycolicibacterium smegmatis 81000.0 1 PMID:17630969 -2.7.4.1 * myxococcus xanthus 82000.0 2 PMID:29127456 -2.7.4.1 * nocardioides dokdonensis 41000.0 1 PMID:31907778 -2.7.4.1 * propionibacterium freudenreichii subsp. shermanii 85000.0 2 PMID:3031044 -2.7.4.1 * pseudomonas aeruginosa 164000.0 3 PMID:10224002;PMID:12482933;PMID:19001261 -2.7.4.1 * rhodocyclus sp. 75000.0 1 PMID:12324346 -2.7.4.1 * ruegeria pomeroyi 39950.0 3 PMID:24930102 -2.7.4.1 * serratia marcescens 70000.0 1 PMID:12882570 -2.7.4.1 * sinorhizobium meliloti 124500.0 1 PMID:19001261 -2.7.4.1 * sulfolobus acidocaldarius 57000.0 1 PMID:2549015 -2.7.4.10 * bos taurus 52000.0 1 PMID:5423264 -2.7.4.10 * clonorchis sinensis 26060.0 1 PMID:15747033 -2.7.4.10 * plasmodium falciparum 30000.0 2 PMID:15478799;PMID:22684067 -2.7.4.13 * saccharomyces cerevisiae 24690.0 4 PMID:16240436 -2.7.4.13 * tequatrovirus t4 22000.0 1 PMID:6853543 -2.7.4.13 * tequintavirus t5 29140.0 4 PMID:12597877;PMID:14711503 -2.7.4.14 * arabidopsis thaliana 22448.0 1 PMID:9576794 -2.7.4.14 * dictyostelium discoideum 22000.0 1 PMID:18602116;PMID:27558661 -2.7.4.14 * homo sapiens 22222.0 2 PMID:11681623;PMID:18602116;PMID:27558661 -2.7.4.14 * rattus norvegicus 26000.0 2 PMID:3010881 -2.7.4.14 * saccharomyces cerevisiae 26000.0 1 PMID:3010881 -2.7.4.15 * bos taurus 103000.0 1 PMID:3010036 -2.7.4.16 * salmonella enterica subsp. enterica serovar typhimurium 35000.0 1 PMID:9188462 -2.7.4.2 * catharanthus roseus 128000.0 1 * -2.7.4.2 * enterococcus faecalis 81000.0 4 PMID:15802646 -2.7.4.2 * homo sapiens 24200.0 3 PMID:16519518;PMID:23146631 -2.7.4.2 * saccharolobus solfataricus 36200.0 1 PMID:23378249 -2.7.4.2 * streptococcus pneumoniae 37747.0 1 PMID:12001237 -2.7.4.2 * sus scrofa 22500.0 3 PMID:2991707;PMID:6248100 -2.7.4.21 * homo sapiens 50000.0 2 PMID:11896621;PMID:21652713 -2.7.4.21 * mus musculus 55000.0 2 PMID:23255604;PMID:23782934;PMID:27140681 -2.7.4.21 * rattus norvegicus 60000.0 2 PMID:8633060 -2.7.4.21 * xenopus sp. 57000.0 1 PMID:10567691 -2.7.4.22 * bacillus subtilis 154000.0 5 PMID:12869195 -2.7.4.22 * escherichia coli 482900.0 11 PMID:22528139;PMID:7711027;PMID:8679525;PMID:9457846;PMID:9922246 -2.7.4.22 * helicobacter pylori 27500.0 1 PMID:20602229 -2.7.4.22 * mycobacterium tuberculosis 173200.0 1 PMID:21149268 -2.7.4.22 * saccharolobus solfataricus 140000.0 2 PMID:17297917 -2.7.4.22 * staphylococcus aureus 150000.0 2 PMID:22528139;PMID:8679525;PMID:9457846 -2.7.4.22 * streptococcus pneumoniae 189000.0 3 PMID:15324307 -2.7.4.23 * escherichia coli 23500.0 2 PMID:12700258 -2.7.4.24 * homo sapiens 160000.0 2 PMID:17702752 -2.7.4.24 * rattus norvegicus 400000.0 5 PMID:17702752;PMID:9778378 -2.7.4.25 * escherichia coli k-12 25000.0 3 PMID:17542990;PMID:7836281;PMID:8576266 -2.7.4.25 * mycobacterium tuberculosis 24060.0 3 PMID:19181797 -2.7.4.25 * ureaplasma parvum 30000.0 1 PMID:17355283 -2.7.4.26 * haloferax volcanii 26417.0 1 PMID:24375100 -2.7.4.27 * zea mays 180000.0 10 PMID:16696949;PMID:2983615;PMID:3040758;PMID:8311453 -2.7.4.28 * escherichia coli 25000.0 1 PMID:20044937 -2.7.4.3 * ancylobacter novellus 47800.0 3 * -2.7.4.3 * arabidopsis thaliana 22600.0 1 PMID:23121860 -2.7.4.3 * bacillus subtilis 24100.0 1 PMID:8061005 -2.7.4.3 * bos taurus 25600.0 4 PMID:207226 -2.7.4.3 * cereibacter sphaeroides 34400.0 2 * -2.7.4.3 * chlamydia pneumoniae 24000.0 1 PMID:11278507 -2.7.4.3 * clonorchis sinensis 26700.0 1 PMID:23455935 -2.7.4.3 * cyprinus carpio 22000.0 1 PMID:164348 -2.7.4.3 * desulfovibrio desulfuricans 26000.0 3 PMID:18328566;PMID:213322 -2.7.4.3 * doryteuthis pealeii 27000.0 1 PMID:12179 -2.7.4.3 * drosophila melanogaster 50000.0 5 PMID:18294127;PMID:19416704 -2.7.4.3 * escherichia coli 23560.0 3 PMID:2832615;PMID:3027060 -2.7.4.3 * gallus gallus 28000.0 3 PMID:31204977;PMID:6281013 -2.7.4.3 * geobacillus stearothermophilus 24140.0 2 PMID:1554691 -2.7.4.3 * halothiobacillus neapolitanus 23500.0 1 PMID:4357664 -2.7.4.3 * helicoverpa armigera 33000.0 2 PMID:23020757 -2.7.4.3 * homo sapiens 53000.0 25 PMID:166983;PMID:17662886;PMID:19043416;PMID:19043417;PMID:19766732;PMID:211388;PMID:23416111;PMID:4664934;PMID:5062950;PMID:6182143;PMID:6296114;PMID:9504408 -2.7.4.3 * leishmania donovani 26000.0 1 PMID:14622299 -2.7.4.3 * leuconostoc mesenteroides 26000.0 1 PMID:18328566;PMID:213322 -2.7.4.3 * megalodesulfovibrio gigas 26000.0 5 PMID:15223146;PMID:18328566;PMID:19786047;PMID:213322 -2.7.4.3 * methanocaldococcus jannaschii 25000.0 1 PMID:7768791 -2.7.4.3 * methanococcus voltae 25000.0 1 PMID:23409202;PMID:7768791 -2.7.4.3 * methanothermococcus thermolithotrophicus 25000.0 1 PMID:7768791 -2.7.4.3 * methanotorris igneus 25000.0 1 PMID:7768791 -2.7.4.3 * mus musculus 28000.0 4 PMID:16790685 -2.7.4.3 * mycobacterium marinum 29500.0 1 PMID:3004585 -2.7.4.3 * mycobacterium tuberculosis 25000.0 2 PMID:10398370 -2.7.4.3 * nicotiana tabacum 30000.0 2 * -2.7.4.3 * oryctolagus cuniculus 21000.0 1 * -2.7.4.3 * paralichthys olivaceus 22000.0 1 PMID:31204977 -2.7.4.3 * plasmodium falciparum 34000.0 5 PMID:15478799;PMID:18973776;PMID:22819813 -2.7.4.3 * rattus norvegicus 49000.0 9 PMID:211387;PMID:6244854 -2.7.4.3 * rhodopseudomonas palustris 33500.0 2 * -2.7.4.3 * rhodopseudomonas rubrum 32100.0 2 * -2.7.4.3 * saccharolobus solfataricus 63000.0 2 PMID:12450122 -2.7.4.3 * saccharomyces cerevisiae 41000.0 2 PMID:6245882 -2.7.4.3 * schistosoma mansoni 27200.0 3 PMID:1339355;PMID:22841753 -2.7.4.3 * streptococcus pneumoniae 24000.0 1 PMID:25372811 -2.7.4.3 * strongylocentrotus purpuratus 130000.0 2 PMID:17145754;PMID:17301946;PMID:17761698 -2.7.4.3 * sulfolobus acidocaldarius 52000.0 5 PMID:8274029;PMID:8489243;PMID:8922285 -2.7.4.3 * sus scrofa 26900.0 2 PMID:203453 -2.7.4.3 * thermotoga neapolitana 29000.0 2 PMID:12625835 -2.7.4.3 * tritrichomonas suis 29000.0 1 PMID:2546792 -2.7.4.3 * trypanosoma brucei 24000.0 1 PMID:15657034 -2.7.4.3 * trypanosoma cruzi 25000.0 1 PMID:23409202;PMID:7768791 -2.7.4.3 * vibrio natriegens 32000.0 2 PMID:12625835 -2.7.4.3 * zea mays 31500.0 2 PMID:16664952 -2.7.4.31 * methanocaldococcus jannaschii 24000.0 1 PMID:26100040 -2.7.4.33 * acinetobacter johnsonii 55800.0 2 PMID:15716459;PMID:1655714 -2.7.4.33 * acinetobacter sp. 55000.0 1 PMID:1655714 -2.7.4.33 * meiothermus ruber 32000.0 2 PMID:24532069 -2.7.4.33 * pseudomonas aeruginosa 97000.0 1 PMID:19001261 -2.7.4.34 * pseudomonas aeruginosa 164000.0 1 PMID:12482933 -2.7.4.6 * acanthamoeba polyphaga mimivirus 112000.0 1 PMID:16957983 -2.7.4.6 * avena sativa 100000.0 6 PMID:19259546;PMID:6092068;PMID:8038216 -2.7.4.6 * bacillus subtilis 100000.0 1 * -2.7.4.6 * bos taurus 109000.0 4 PMID:5056081 -2.7.4.6 * brassica rapa subsp. oleifera 25700.0 3 PMID:15055533 -2.7.4.6 * chromohalobacter israelensis 33000.0 2 * -2.7.4.6 * columba livia 66000.0 2 PMID:8016268;PMID:9179842;PMID:9305928 -2.7.4.6 * drosophila melanogaster 63500.0 2 PMID:25195176 -2.7.4.6 * escherichia coli 110000.0 5 PMID:12874011;PMID:1657712;PMID:18324728;PMID:4373447;PMID:6853543 -2.7.4.6 * haloarcula marismortui 111000.0 2 PMID:19486691 -2.7.4.6 * haloarcula quadrata 114000.0 2 PMID:19486691 -2.7.4.6 * halobacterium salinarum 36600.0 2 PMID:17674972 -2.7.4.6 * halomonas sp. 30130.0 2 PMID:17227453 -2.7.4.6 * halomonas sp. #593 32100.0 3 PMID:18319059;PMID:22275000 -2.7.4.6 * homo sapiens 105000.0 9 PMID:19923730;PMID:211386;PMID:2546816;PMID:3024650 -2.7.4.6 * lathyrus oleraceus 70000.0 12 PMID:17340056;PMID:20458498;PMID:3024650 -2.7.4.6 * leishmania amazonensis 68000.0 2 PMID:18242727 -2.7.4.6 * leishmania major 112000.0 5 PMID:16809050;PMID:19923730;PMID:2546816 -2.7.4.6 * macruronus novaezelandiae 16810.0 1 PMID:17622168 -2.7.4.6 * mayetiola destructor 16800.0 1 PMID:29913225 -2.7.4.6 * merluccius australis australis 17800.0 1 PMID:17622168 -2.7.4.6 * merluccius bilinearis 17820.0 1 PMID:17622168 -2.7.4.6 * merluccius capensis 18590.0 1 PMID:17622168 -2.7.4.6 * merluccius gayi 17800.0 1 PMID:17622168 -2.7.4.6 * merluccius hubbsi 17810.0 1 PMID:17622168 -2.7.4.6 * merluccius merluccius 18600.0 1 PMID:17622168 -2.7.4.6 * merluccius paradoxus 18590.0 1 PMID:17622168 -2.7.4.6 * merluccius polli 18600.0 1 PMID:17622168 -2.7.4.6 * merluccius polylepis 17810.0 1 PMID:17622168 -2.7.4.6 * merluccius productus 17870.0 1 PMID:17622168 -2.7.4.6 * merluccius senegalensis 18590.0 1 PMID:17622168 -2.7.4.6 * methanocaldococcus jannaschii 89000.0 1 PMID:11053861 -2.7.4.6 * mycobacterium tuberculosis 107000.0 3 PMID:12581202;PMID:15302878 -2.7.4.6 * mycolicibacterium smegmatis 18000.0 1 PMID:8016268;PMID:9179842;PMID:9305928 -2.7.4.6 * myxococcus xanthus 66000.0 2 PMID:8263923 -2.7.4.6 * natrialba magadii 130000.0 3 PMID:12013434;PMID:15890279;PMID:9783181 -2.7.4.6 * oryza sativa 125000.0 5 PMID:15890279;PMID:21897044;PMID:9783181 -2.7.4.6 * oryza sativa japonica group 23500.0 1 PMID:28863212 -2.7.4.6 * penaeus vannamei 57000.0 2 PMID:25195883;PMID:28505172 -2.7.4.6 * plasmodium falciparum 18000.0 1 PMID:19652368;PMID:27268980 -2.7.4.6 * pseudomonas fluorescens 15000.0 1 PMID:12874011;PMID:18324728 -2.7.4.6 * pseudomonas sp. 62120.0 2 PMID:17227453 -2.7.4.6 * pseudopotamilla occelata 18000.0 1 PMID:19652368;PMID:27268980 -2.7.4.6 * rattus norvegicus 99700.0 7 PMID:1316152;PMID:17922640;PMID:2832402;PMID:8142475 -2.7.4.6 * saccharomyces cerevisiae 70000.0 1 PMID:1659321 -2.7.4.6 * saccharomyces pastorianus 102000.0 3 PMID:4576138 -2.7.4.6 * saccharum officinarum 18000.0 1 PMID:8016268;PMID:9179842;PMID:9305928 -2.7.4.6 * salmonella enterica subsp. enterica serovar typhimurium 85000.0 1 PMID:211385 -2.7.4.6 * solanum chacoense 19300.0 1 PMID:16395585 -2.7.4.6 * spinacia oleracea 110000.0 4 PMID:1849013 -2.7.4.6 * streptomyces coelicolor 66000.0 2 PMID:8706710 -2.7.4.6 * sus scrofa 100000.0 3 PMID:6092068;PMID:6269456;PMID:8038216 -2.7.4.6 * thermus thermophilus 60000.0 2 PMID:14501133 -2.7.4.6 * trypanosoma cruzi 41800.0 2 PMID:28246372 -2.7.4.6 * xenopus laevis 70000.0 3 PMID:2176546 -2.7.4.7 * escherichia coli 33000.0 2 * -2.7.4.8 * bos taurus 23000.0 2 PMID:2551688;PMID:3024975 -2.7.4.8 * brugia malayi 45000.0 2 PMID:25061727 -2.7.4.8 * escherichia coli 88000.0 3 PMID:16140325;PMID:211389 -2.7.4.8 * helianthus tuberosus 72000.0 1 * -2.7.4.8 * homo sapiens 22010.0 4 PMID:10585400;PMID:21515241;PMID:26446352;PMID:8663313 -2.7.4.8 * mus musculus 22000.0 3 PMID:12036965;PMID:8663313 -2.7.4.8 * rattus norvegicus 20500.0 1 PMID:4307347 -2.7.4.8 * saccharomyces cerevisiae 25000.0 3 PMID:2551688;PMID:3024975;PMID:6118179 -2.7.4.8 * staphylococcus aureus 24000.0 1 PMID:17012781 -2.7.4.9 * equid alphaherpesvirus 4 36500.0 1 PMID:14527394 -2.7.4.9 * escherichia coli 65000.0 3 PMID:4899016;PMID:9696781 -2.7.4.9 * gallus gallus 46000.0 1 PMID:236732 -2.7.4.9 * homo sapiens 50000.0 2 PMID:24556140;PMID:2538159 -2.7.4.9 * mus musculus 33000.0 1 PMID:4711469 -2.7.4.9 * mycobacterium tuberculosis 46600.0 2 PMID:11369858 -2.7.4.9 * plasmodium falciparum 25000.0 1 PMID:22425904;PMID:6088527 -2.7.4.9 * saccharomyces cerevisiae 52000.0 4 PMID:19540237;PMID:22425904;PMID:6088527 -2.7.4.9 * strongylocentrotus intermedius 100000.0 1 PMID:9986917 -2.7.4.9 * thermus thermophilus 22000.0 1 PMID:23385749 -2.7.4.9 * wolbachia endosymbiont of brugia malayi 52000.0 2 PMID:24556140;PMID:2538159 -2.7.6.1 * [bacillus] caldolyticus 34497.0 1 PMID:15560793 -2.7.6.1 * bacillus amyloliquefaciens 186000.0 1 PMID:22083279 -2.7.6.1 * bacillus subtilis 280000.0 2 PMID:2169413 -2.7.6.1 * bos taurus 50000.0 4 PMID:10395979 -2.7.6.1 * escherichia coli 34288.0 1 * -2.7.6.1 * hevea brasiliensis 200000.0 2 PMID:12223847 -2.7.6.1 * homo sapiens 1200000.0 10 PMID:11550793;PMID:169259;PMID:8387514 -2.7.6.1 * methanocaldococcus jannaschii 147000.0 2 PMID:16288921 -2.7.6.1 * mycobacterium tuberculosis 220000.0 2 PMID:21085589 -2.7.6.1 * mycolicibacterium smegmatis 221000.0 1 PMID:28419153 -2.7.6.1 * pyrobaculum calidifontis 32000.0 1 PMID:27517698 -2.7.6.1 * rattus norvegicus 1200000.0 15 PMID:1651917;PMID:211372;PMID:2546925;PMID:4358634;PMID:7572345;PMID:9348095 -2.7.6.1 * saccharolobus solfataricus 34000.0 1 PMID:25605536 -2.7.6.1 * salmonella enterica subsp. enterica serovar typhimurium 600000.0 8 PMID:170262;PMID:211378;PMID:4306285 -2.7.6.1 * thermoplasma volcanium 55000.0 1 PMID:21963988 -2.7.6.1 * thermus thermophilus 158000.0 2 * -2.7.6.2 * glycine max 49000.0 1 PMID:16661427 -2.7.6.2 * homo sapiens 61000.0 2 PMID:12953792 -2.7.6.2 * paracoccus denitrificans 230000.0 3 PMID:6251035 -2.7.6.2 * petroselinum crispum 30000.0 1 PMID:173819;PMID:220503 -2.7.6.2 * plasmodium falciparum 47000.0 3 PMID:17132104 -2.7.6.3 * arabidopsis thaliana 54053.0 1 PMID:17289662 -2.7.6.3 * escherichia coli 150000.0 3 PMID:1657875;PMID:21222642;PMID:7950384 -2.7.6.3 * francisella tularensis 53000.0 2 PMID:21152407 -2.7.6.3 * haemophilus influenzae 20000.0 2 PMID:10080886 -2.7.6.3 * plasmodium chabaudi 190000.0 1 PMID:4435732;PMID:7374502 -2.7.6.3 * plasmodium falciparum 330000.0 2 PMID:15279950 -2.7.6.3 * pneumocystis carinii 69000.0 1 PMID:8397083 -2.7.6.4 * streptomyces adephospholyticus 29000.0 3 * -2.7.6.4 * streptomyces aspergilloides 23000.0 2 PMID:1259517 -2.7.6.4 * streptomyces hachijoensis 18000.0 1 PMID:1259517 -2.7.6.4 * streptomyces morookaense 25000.0 3 PMID:1088;PMID:1259517;PMID:26674 -2.7.6.4 * streptomyces septatus 21000.0 1 PMID:1259517 -2.7.6.4 * streptomyces violascens 26000.0 1 PMID:1259517 -2.7.6.5 * brevibacillus brevis 55000.0 1 PMID:184817 -2.7.6.5 * escherichia coli 83860.0 1 PMID:2844820 -2.7.6.5 * francisella tularensis subsp. tularensis 148000.0 3 PMID:26450927 -2.7.6.5 * geobacillus stearothermophilus 86000.0 2 PMID:6161916 -2.7.6.5 * mycobacterium tuberculosis 245000.0 3 PMID:16026164 -2.7.6.5 * streptomyces antibioticus 88000.0 2 PMID:8113189 -2.7.7.1 * arabidopsis thaliana 24500.0 1 PMID:19273075 -2.7.7.1 * bos taurus 133000.0 2 PMID:7654174 -2.7.7.1 * gallus gallus 300000.0 1 PMID:16567 -2.7.7.1 * giardia duodenalis 28100.0 2 * -2.7.7.1 * homo sapiens 132000.0 18 PMID:11027696;PMID:12359228;PMID:1524439;PMID:17402747;PMID:19273075;PMID:20388704;PMID:20943658 -2.7.7.1 * katsuwonus pelamis 200000.0 1 PMID:2827621;PMID:2832206;PMID:3013296 -2.7.7.1 * leishmania braziliensis 41980.0 1 PMID:32322725 -2.7.7.1 * methanocaldococcus jannaschii 72000.0 3 PMID:11265471;PMID:15078171;PMID:9401030 -2.7.7.1 * mus musculus 64000.0 2 PMID:20943658;PMID:32250733 -2.7.7.1 * pyrococcus horikoshii 77000.0 1 * -2.7.7.1 * saccharolobus solfataricus 66000.0 4 PMID:11265470;PMID:11265471;PMID:15078171;PMID:7988679;PMID:9211320;PMID:9401030 -2.7.7.1 * saccharomyces cerevisiae 200000.0 8 PMID:10428462;PMID:15078171;PMID:19273075;PMID:2827621;PMID:2832206;PMID:3013296;PMID:9211320 -2.7.7.1 * thermus thermophilus 77800.0 1 PMID:29175123 -2.7.7.10 * bifidobacterium bifidum 200000.0 2 PMID:500588 -2.7.7.10 * cucumis melo 68000.0 2 * -2.7.7.10 * entamoeba histolytica 40000.0 1 PMID:6304512 -2.7.7.101 * bacillus subtilis 69000.0 1 * -2.7.7.101 * mycobacterium tuberculosis 35000.0 1 PMID:30315069 -2.7.7.12 * bifidobacterium bifidum 110000.0 3 PMID:24014529 -2.7.7.12 * escherichia coli 80000.0 5 PMID:12418221;PMID:232062;PMID:5338129;PMID:6294449;PMID:7873670 -2.7.7.12 * galdieria sulphuraria 82000.0 3 PMID:8529650 -2.7.7.12 * homo sapiens 88000.0 7 PMID:6260202;PMID:6272638;PMID:6287937;PMID:736561;PMID:9450900 -2.7.7.12 * pyrobaculum aerophilum 59000.0 2 PMID:22442236 -2.7.7.12 * saccharomyces cerevisiae 86100.0 2 PMID:387754;PMID:6292668 -2.7.7.13 * burkholderia cenocepacia 56000.0 2 PMID:18668237 -2.7.7.13 * burkholderia cepacia 55300.0 2 PMID:17184737 -2.7.7.13 * candida albicans 39974.0 1 PMID:10913825 -2.7.7.13 * helicobacter pylori 55303.0 2 PMID:12023023 -2.7.7.13 * leishmania mexicana 46400.0 1 PMID:11447107 -2.7.7.13 * leptospira interrogans serovar copenhageni 45000.0 1 PMID:20035319 -2.7.7.13 * malpighia glabra 39700.0 1 PMID:17764967 -2.7.7.13 * mycolicibacterium smegmatis 70000.0 2 PMID:9989944 -2.7.7.13 * nakaseomyces glabratus 39298.0 1 PMID:10913825 -2.7.7.13 * pseudomonas aeruginosa 56000.0 2 PMID:1846611 -2.7.7.13 * pyrococcus furiosus 53000.0 1 PMID:19421452 -2.7.7.13 * pyrococcus horikoshii 52900.0 1 PMID:26290359 -2.7.7.13 * saccharolobus solfataricus 42000.0 2 PMID:15145064 -2.7.7.13 * saccharomyces cerevisiae 39565.0 1 PMID:9195935 -2.7.7.13 * salmonella enterica 108000.0 3 PMID:8922954 -2.7.7.13 * sus scrofa 450000.0 5 PMID:11082198;PMID:2983993;PMID:7688733 -2.7.7.13 * trypanosoma brucei 42000.0 1 PMID:19919534 -2.7.7.14 * homo sapiens 50000.0 1 PMID:17612623 -2.7.7.14 * mus musculus 110000.0 8 PMID:17325045;PMID:17612623;PMID:17646670;PMID:23354482 -2.7.7.14 * rattus norvegicus 120000.0 3 PMID:1323040;PMID:17612623;PMID:241749;PMID:8385107 -2.7.7.14 * trypanosoma brucei 44623.0 1 PMID:19555461 -2.7.7.15 * drosophila melanogaster 44000.0 1 PMID:15238222 -2.7.7.15 * lathyrus oleraceus 56000.0 1 * -2.7.7.15 * mus musculus 80000.0 2 PMID:17804406 -2.7.7.15 * plasmodium falciparum 48000.0 1 * -2.7.7.15 * rattus norvegicus 840000.0 18 PMID:10224101;PMID:1323039;PMID:15069071;PMID:15713672;PMID:19684306;PMID:2542297;PMID:2557076;PMID:3007491;PMID:3036843;PMID:914832 -2.7.7.15 * ricinus communis 155000.0 2 PMID:16667443 -2.7.7.15 * saccharomyces cerevisiae 60000.0 2 PMID:11162399 -2.7.7.15 * streptococcus pneumoniae 30000.0 1 PMID:11466299 -2.7.7.18 * arabidopsis thaliana 24500.0 1 PMID:19273075 -2.7.7.18 * bacillus anthracis 23347.0 1 PMID:18931430 -2.7.7.18 * bacillus subtilis 49140.0 1 PMID:11704676 -2.7.7.18 * giardia duodenalis 28100.0 2 * -2.7.7.18 * homo sapiens 34439.0 1 PMID:19273075 -2.7.7.18 * leishmania braziliensis 41980.0 1 PMID:32322725 -2.7.7.18 * mus musculus 64000.0 1 PMID:32250733 -2.7.7.18 * mycobacterium tuberculosis 54000.0 2 PMID:25631047 -2.7.7.18 * plasmodium falciparum 26000.0 1 PMID:24747974 -2.7.7.18 * saccharomyces cerevisiae 48000.0 1 PMID:19273075 -2.7.7.18 * staphylococcus aureus 44000.0 1 PMID:16784754 -2.7.7.18 * streptococcus pyogenes 24350.0 1 PMID:23204464 -2.7.7.18 * thermus thermophilus 77800.0 1 PMID:29175123 -2.7.7.19 * artemia salina 70000.0 1 PMID:2982613 -2.7.7.19 * artemia sp. 70000.0 1 * -2.7.7.19 * bacillus subtilis 86000.0 2 PMID:9137836 -2.7.7.19 * bos taurus 160000.0 10 PMID:1756732;PMID:1896071;PMID:1993684;PMID:237901;PMID:4718742;PMID:6252200;PMID:9061026 -2.7.7.19 * cricetulus griseus 155000.0 2 * -2.7.7.19 * drosophila melanogaster 180000.0 1 PMID:18434412 -2.7.7.19 * escherichia coli 58000.0 4 PMID:4580885;PMID:8915528 -2.7.7.19 * homo sapiens 94000.0 15 PMID:11463842;PMID:1191706;PMID:2538718;PMID:2555686;PMID:8717411;PMID:893453 -2.7.7.19 * mesocricetus auratus 155000.0 4 PMID:27216 -2.7.7.19 * mus musculus 200000.0 7 PMID:16325797;PMID:18281463;PMID:18294465;PMID:237910 -2.7.7.19 * orthopoxvirus vaccinia 80000.0 6 PMID:237910;PMID:893453 -2.7.7.19 * pseudomonas putida 185000.0 2 PMID:1191706 -2.7.7.19 * rattus norvegicus 64000.0 5 PMID:183950;PMID:235943;PMID:2852961 -2.7.7.19 * saccharomyces cerevisiae 63000.0 2 PMID:2026590 -2.7.7.19 * tetrahymena pyriformis 95000.0 2 PMID:118167 -2.7.7.19 * triticum aestivum 70000.0 2 PMID:2852961 -2.7.7.19 * vigna radiata 120000.0 2 * -2.7.7.19 * vigna unguiculata 63000.0 1 * -2.7.7.2 * arabidopsis thaliana 34200.0 6 PMID:18713732 -2.7.7.2 * bacillus subtilis 36000.0 5 PMID:9473052 -2.7.7.2 * corynebacterium ammoniagenes 38000.0 5 PMID:20054130;PMID:23291469;PMID:24170887;PMID:7772835 -2.7.7.2 * homo sapiens 65300.0 12 PMID:16643857;PMID:17049878;PMID:20060505;PMID:29316637 -2.7.7.2 * methanocaldococcus jannaschii 29000.0 2 PMID:20822113 -2.7.7.2 * rattus norvegicus 325000.0 4 PMID:3034893;PMID:6298797;PMID:9211336 -2.7.7.2 * saccharomyces cerevisiae 36000.0 2 PMID:7799934 -2.7.7.2 * streptomyces davaonensis 34000.0 1 PMID:18156273 -2.7.7.22 * pogonatherum paniceum 39680.0 1 PMID:27442366 -2.7.7.23 * arabidopsis thaliana 60000.0 3 PMID:20557289 -2.7.7.23 * candida albicans 54700.0 1 PMID:17392279 -2.7.7.23 * escherichia coli 53000.0 9 PMID:11084021;PMID:8083170;PMID:8689233 -2.7.7.23 * giardia duodenalis 66000.0 7 PMID:15951138;PMID:16169849;PMID:9763295 -2.7.7.23 * homo sapiens 64000.0 2 PMID:9765219 -2.7.7.23 * locusta migratoria 55800.0 2 PMID:23977188 -2.7.7.23 * moniliophthora perniciosa 52922.0 1 * -2.7.7.23 * neisseria gonorrhoeae 50000.0 2 PMID:7592484 -2.7.7.23 * neurospora crassa 37000.0 1 PMID:43769 -2.7.7.23 * oryza sativa japonica group 54071.0 1 PMID:25399020 -2.7.7.23 * saccharomyces cerevisiae 40000.0 2 PMID:43769 -2.7.7.23 * sus scrofa 125000.0 4 PMID:8662687;PMID:9765219 -2.7.7.23 * yersinia pseudotuberculosis 52965.0 1 PMID:25417006 -2.7.7.24 * mycobacterium tuberculosis 33700.0 3 PMID:21940712;PMID:9084178 -2.7.7.24 * niallia circulans 31810.0 1 PMID:15701005 -2.7.7.24 * pseudomonas aeruginosa 122000.0 3 PMID:11053865 -2.7.7.24 * saccharothrix syringae 142900.0 2 PMID:34819927 -2.7.7.24 * streptomyces antibioticus 43000.0 1 * -2.7.7.24 * streptomyces globisporus 48000.0 1 PMID:14987060 -2.7.7.24 * streptomyces sp. 56000.0 3 PMID:15179042;PMID:18051285 -2.7.7.27 * aeromonas hydrophila 200000.0 1 PMID:6331331 -2.7.7.27 * agrobacterium tumefaciens 50000.0 1 PMID:12135365;PMID:1325205;PMID:16662422;PMID:345767;PMID:826540 -2.7.7.27 * anabaena sp. 225000.0 4 PMID:12135365;PMID:1325205;PMID:14520572;PMID:16662422;PMID:16668507;PMID:22961847;PMID:345767;PMID:826540 -2.7.7.27 * arabidopsis thaliana 210000.0 3 PMID:8016263 -2.7.7.27 * cereibacter sphaeroides 204000.0 4 PMID:10562432;PMID:6178721 -2.7.7.27 * chlamydomonas reinhardtii 210000.0 3 PMID:8016263 -2.7.7.27 * escherichia coli 210000.0 5 PMID:12135365;PMID:1325205;PMID:16662422;PMID:2846559;PMID:345767;PMID:4369095;PMID:6263861;PMID:826540 -2.7.7.27 * hafnia alvei 200000.0 1 PMID:6331331 -2.7.7.27 * hordeum vulgare 240000.0 4 PMID:25276800;PMID:9426234 -2.7.7.27 * nitrosomonas europaea 200000.0 3 PMID:14520572;PMID:22961847 -2.7.7.27 * oryza sativa 240000.0 1 * -2.7.7.27 * oryza sativa japonica group 56104.0 1 PMID:25276800 -2.7.7.27 * ostreococcus tauri 222000.0 4 PMID:19737928 -2.7.7.27 * rhodococcus jostii 190000.0 1 PMID:27313571 -2.7.7.27 * rhodocyclus tenuis 215000.0 2 PMID:4369095;PMID:6263861 -2.7.7.27 * rhodospirillum rubrum 200000.0 2 PMID:12135365;PMID:1325205;PMID:16662422;PMID:345767;PMID:826540 -2.7.7.27 * salmonella enterica subsp. enterica serovar typhimurium 195000.0 3 PMID:6156933 -2.7.7.27 * serratia marcescens 186000.0 2 PMID:345767 -2.7.7.27 * solanum lycopersicum 200000.0 4 PMID:2846559 -2.7.7.27 * solanum tuberosum 240000.0 13 PMID:11018533;PMID:12135365;PMID:1325205;PMID:14520572;PMID:16662422;PMID:18252705;PMID:18641076;PMID:19876371;PMID:22961847;PMID:345767;PMID:7480324;PMID:826540 -2.7.7.27 * spinacia oleracea 240000.0 4 PMID:16662079 -2.7.7.27 * streptomyces coelicolor 180000.0 2 PMID:22210767 -2.7.7.27 * synechocystis sp. 216000.0 3 PMID:16668507;PMID:16668879 -2.7.7.27 * thermus caldophilus 230000.0 2 PMID:16665182;PMID:8921008 -2.7.7.27 * triticum aestivum 210000.0 6 PMID:11855648;PMID:25276800 -2.7.7.27 * zea mays 400000.0 10 PMID:14520572;PMID:16659070;PMID:16665182;PMID:758958;PMID:8921008;PMID:9789090 -2.7.7.3 * corynebacterium ammoniagenes 108000.0 2 PMID:8389542 -2.7.7.3 * enterococcus faecalis 120000.0 1 PMID:17077496 -2.7.7.3 * escherichia coli 108000.0 4 PMID:10480925;PMID:14684898 -2.7.7.3 * helicobacter pylori 128600.0 3 PMID:21527250 -2.7.7.3 * mycobacterium tuberculosis 17028.0 1 * -2.7.7.3 * pyrococcus abyssi 20000.0 4 PMID:12756245;PMID:15642482 -2.7.7.3 * sus scrofa 118000.0 5 PMID:11994049;PMID:4018266;PMID:6312972 -2.7.7.3 * thermus thermophilus 67000.0 2 PMID:14684898 -2.7.7.30 * arabidopsis thaliana 116400.0 1 PMID:18199744 -2.7.7.30 * bacteroides fragilis 440159.0 2 PMID:30242642 -2.7.7.30 * homo sapiens 66600.0 1 PMID:16582493 -2.7.7.30 * sus scrofa 61000.0 1 PMID:9804772 -2.7.7.30 * vitis vinifera 118800.0 1 PMID:22949207 -2.7.7.31 * bos taurus 79000.0 9 PMID:16771444;PMID:19082971;PMID:3438251;PMID:5543689;PMID:7263682 -2.7.7.31 * gallus gallus 45000.0 1 PMID:7051783 -2.7.7.31 * homo sapiens 62000.0 2 PMID:16771444;PMID:19082971;PMID:468845;PMID:7263682 -2.7.7.31 * mus musculus 67000.0 2 PMID:16771444;PMID:19082971;PMID:7263682 -2.7.7.31 * oncorhynchus mykiss 57000.0 1 PMID:9271626 -2.7.7.31 * rattus norvegicus 67000.0 2 PMID:16771444;PMID:19082971;PMID:7263682 -2.7.7.31 * sus scrofa 57000.0 3 PMID:7338513 -2.7.7.31 * triticum aestivum 500000.0 1 PMID:7470090 -2.7.7.32 * enterococcus faecalis 100000.0 1 PMID:14085355 -2.7.7.33 * salmonella enterica 31000.0 2 PMID:8276783 -2.7.7.33 * streptomyces sp. 139 30900.0 1 PMID:19330326 -2.7.7.33 * yersinia pseudotuberculosis 120000.0 4 PMID:4833746;PMID:8144449 -2.7.7.38 * aquifex aeolicus 53000.0 2 PMID:21826242 -2.7.7.38 * escherichia coli 46000.0 9 PMID:11545592;PMID:6259128;PMID:6285137;PMID:7606392;PMID:7875563 -2.7.7.38 * zea mays 29000.0 1 PMID:10829033 -2.7.7.39 * bacillus subtilis 30900.0 3 PMID:8393871 -2.7.7.4 * acidithiobacillus ferrooxidans 64500.0 2 PMID:23055613 -2.7.7.4 * allium cepa 51810.0 3 PMID:17692849 -2.7.7.4 * aquifex aeolicus 260000.0 2 PMID:12361716;PMID:3034891 -2.7.7.4 * archaeoglobus fulgidus 150000.0 4 PMID:9627961 -2.7.7.4 * aspergillus nidulans 65000.0 1 PMID:2162344 -2.7.7.4 * brassica capitata 108000.0 1 PMID:16662476 -2.7.7.4 * camellia sinensis 70200.0 4 PMID:18657428 -2.7.7.4 * desulfovibrio desulfuricans 138000.0 3 PMID:18607083;PMID:9819214 -2.7.7.4 * euglena gracilis 66000.0 3 PMID:1904773 -2.7.7.4 * geobacillus stearothermophilus 100000.0 2 * -2.7.7.4 * glycine max 52000.0 2 PMID:16684499 -2.7.7.4 * homo sapiens 133000.0 1 PMID:22242175 -2.7.7.4 * megalodesulfovibrio gigas 151000.0 1 PMID:9819214 -2.7.7.4 * neurospora crassa 63000.0 1 PMID:2162344 -2.7.7.4 * penicillium chrysogenum 440000.0 5 PMID:2162344;PMID:2997125 -2.7.7.4 * penicillium duponti 440000.0 2 PMID:2162344;PMID:2997125 -2.7.7.4 * rattus norvegicus 410000.0 6 PMID:12361716;PMID:2162344;PMID:2537056;PMID:3034891;PMID:718962 -2.7.7.4 * rhodovulum sulfidophilum 290000.0 1 * -2.7.7.4 * saccharomyces cerevisiae 470000.0 3 PMID:10092498;PMID:2162344 -2.7.7.4 * spinacia oleracea 170000.0 4 PMID:2162344;PMID:8274013 -2.7.7.4 * synechococcus sp. 85000.0 1 * -2.7.7.4 * zea mays 42000.0 1 PMID:16658609 -2.7.7.40 * bacillus subtilis 25000.0 1 PMID:23027746 -2.7.7.40 * haemophilus influenzae 106400.0 3 PMID:10094675;PMID:15362865 -2.7.7.40 * staphylococcus aureus 129000.0 3 PMID:15362865 -2.7.7.41 * arabidopsis thaliana 48600.0 1 PMID:9085581 -2.7.7.41 * escherichia coli 27570.0 2 PMID:1323037 -2.7.7.41 * homo sapiens 53226.0 1 PMID:9115637 -2.7.7.41 * mus musculus 52900.0 2 PMID:16023307 -2.7.7.41 * saccharomyces cerevisiae 400000.0 2 PMID:2822695;PMID:350877;PMID:9370328 -2.7.7.41 * solanum tuberosum 49100.0 1 PMID:9085581 -2.7.7.41 * trypanosoma brucei brucei 46000.0 1 PMID:24533860 -2.7.7.42 * escherichia coli 145000.0 4 PMID:4094;PMID:4402680;PMID:4920894 -2.7.7.42 * rhodospirillum rubrum 126200.0 1 PMID:17419734 -2.7.7.43 * [haemophilus] ducreyi 25600.0 3 PMID:18716769;PMID:8663048 -2.7.7.43 * acetivibrio thermocellus 26000.0 1 PMID:17602221;PMID:18716769 -2.7.7.43 * aedes aegypti 1048000.0 1 PMID:27986833 -2.7.7.43 * bos taurus 158000.0 2 PMID:10207180 -2.7.7.43 * danio rerio 236100.0 5 PMID:22351762 -2.7.7.43 * drosophila melanogaster 27500.0 1 PMID:16537535 -2.7.7.43 * escherichia coli 50000.0 2 PMID:18716769;PMID:2826425 -2.7.7.43 * mannheimia haemolytica 135000.0 3 PMID:11577688;PMID:18716769 -2.7.7.43 * mus musculus 175800.0 8 PMID:11479279;PMID:19666032;PMID:9689047 -2.7.7.43 * neisseria meningitidis 33700.0 5 PMID:12135555;PMID:18716769 -2.7.7.43 * oncorhynchus mykiss 160000.0 3 PMID:11479279;PMID:8338634 -2.7.7.43 * pelophylax lessonae 164000.0 2 PMID:6253375 -2.7.7.43 * photobacterium leiognathi 60000.0 2 PMID:21228490 -2.7.7.43 * rattus norvegicus 116000.0 3 PMID:1577759 -2.7.7.44 * glycine max 71000.0 1 * -2.7.7.45 * artemia franciscana 110000.0 1 PMID:12418232;PMID:9882433 -2.7.7.45 * artemia salina 490000.0 1 PMID:4208243 -2.7.7.45 * artemia sp. 480000.0 3 PMID:7958281;PMID:8163476 -2.7.7.46 * escherichia coli 32500.0 2 PMID:6324682 -2.7.7.47 * bacillus subtilis 35000.0 1 * -2.7.7.47 * corynebacterium glutamicum 31000.0 1 PMID:12383729 -2.7.7.47 * escherichia coli 49000.0 1 PMID:15721775 -2.7.7.47 * pseudomonas aeruginosa 30000.0 1 PMID:8858861 -2.7.7.48 * bamboo mosaic virus 155000.0 1 PMID:9811749 -2.7.7.48 * dengue virus 104000.0 3 PMID:17301146;PMID:25921066 -2.7.7.48 * ectropis obliqua picorna-like virus 68000.0 2 PMID:20423615 -2.7.7.48 * gossypium hirsutum 127900.0 1 PMID:17929195 -2.7.7.48 * grapevine leafroll-associated virus 58200.0 1 PMID:19115034 -2.7.7.48 * hepacivirus hominis 82000.0 4 PMID:19220662;PMID:20060472;PMID:8598194 -2.7.7.48 * influenza virus a/pr8 250000.0 1 PMID:2358436 -2.7.7.48 * japanese encephalitis virus 105000.0 2 PMID:17577613;PMID:17623110 -2.7.7.48 * maize dwarf mosaic virus 160000.0 1 * -2.7.7.48 * mengo virus 52000.0 1 PMID:23379565 -2.7.7.48 * qubevirus durum 700000.0 6 * -2.7.7.48 * rhinovirus a16 54000.0 1 PMID:12367717 -2.7.7.48 * rhinovirus a2 64000.0 1 PMID:2981346 -2.7.7.48 * sapovirus 57000.0 1 PMID:17121797 -2.7.7.48 * solanum lycopersicum 128000.0 2 PMID:7685022 -2.7.7.48 * vigna unguiculata 120000.0 1 PMID:18635112 -2.7.7.49 * avian myeloblastosis virus 170000.0 1 PMID:66065 -2.7.7.49 * avian sarcoma virus 95000.0 2 PMID:66065 -2.7.7.49 * escherichia coli 67227.0 2 * -2.7.7.49 * gibbon ape leukemia virus 68000.0 1 * -2.7.7.49 * hamster leukemia virus 120000.0 3 PMID:66065 -2.7.7.49 * htlv-iii 98000.0 1 PMID:2419171 -2.7.7.49 * human immunodeficiency virus 1 66000.0 10 PMID:18255184;PMID:20929562;PMID:23149716 -2.7.7.49 * mason-pfizer monkey virus 100000.0 1 * -2.7.7.49 * moloney murine leukemia virus 71000.0 1 PMID:2410413 -2.7.7.49 * mouse mammary tumor virus 100000.0 2 PMID:9445385 -2.7.7.49 * rauscher murine leukemia virus 90000.0 2 * -2.7.7.49 * reticuloendotheliosis virus 84000.0 1 * -2.7.7.49 * simian immunodeficiency virus 130000.0 3 PMID:1691922 -2.7.7.49 * squirrel monkey retrovirus 100000.0 1 * -2.7.7.49 * streptococcus agalactiae 103000.0 1 PMID:18706966 -2.7.7.49 * tetrahymena thermophila 40000.0 1 PMID:23760279 -2.7.7.49 * woolly monkey sarcoma virus 70000.0 1 * -2.7.7.5 * prosthecochloris vibrioformis 120000.0 1 * -2.7.7.5 * thiobacillus denitrificans 82000.0 4 PMID:10636864 -2.7.7.50 * autographa californica nucleopolyhedrovirus 114200.0 2 PMID:9811738 -2.7.7.50 * bos taurus 65000.0 1 PMID:6329686 -2.7.7.50 * chikungunya virus 61000.0 1 PMID:27427769 -2.7.7.50 * homo sapiens 69000.0 2 PMID:23349942;PMID:7358712 -2.7.7.50 * kluyveromyces lactis 67000.0 1 PMID:11427964 -2.7.7.50 * mammalian orthoreovirus 3 42000.0 1 PMID:10644745 -2.7.7.50 * mus musculus 68000.0 3 PMID:9545288 -2.7.7.50 * orthopoxvirus vaccinia 127000.0 7 PMID:1194286;PMID:2164022;PMID:659428 -2.7.7.50 * rattus norvegicus 65000.0 1 * -2.7.7.50 * saccharomyces cerevisiae 180000.0 7 PMID:3029058;PMID:6389537 -2.7.7.50 * trypanosoma brucei 42000.0 1 PMID:17416901 -2.7.7.51 * auxenochlorella pyrenoidosa 65000.0 4 PMID:6274307 -2.7.7.51 * chlorella sp. 65000.0 4 PMID:6274307 -2.7.7.52 * crithidia fasciculata 43000.0 1 * -2.7.7.52 * homo sapiens 115000.0 2 PMID:12603330;PMID:2417240 -2.7.7.52 * leishmania tarentolae 140000.0 2 PMID:11893335;PMID:18191648 -2.7.7.52 * trypanosoma brucei 700000.0 4 PMID:11893335;PMID:12820966;PMID:17189640 -2.7.7.52 * vigna unguiculata 50500.0 1 PMID:6269049 -2.7.7.53 * dolichospermum flos-aquae 32000.0 1 PMID:9003364 -2.7.7.53 * euglena gracilis 30000.0 1 PMID:21137581 -2.7.7.53 * mycobacterium avium 24500.0 1 PMID:25940844 -2.7.7.53 * mycobacterium tuberculosis 100000.0 2 PMID:19778616 -2.7.7.53 * mycolicibacterium smegmatis 22500.0 1 PMID:25940844 -2.7.7.53 * saccharomyces cerevisiae 40000.0 2 PMID:2982863;PMID:7642617 -2.7.7.53 * synechococcus sp. 39000.0 1 PMID:9003364 -2.7.7.53 * tetradesmus obliquus 48000.0 2 PMID:8198532 -2.7.7.53 * trichormus variabilis 32000.0 1 PMID:9003364 -2.7.7.56 * escherichia coli 200000.0 3 PMID:1512252;PMID:1512253;PMID:2455297 -2.7.7.56 * streptomyces coelicolor 26400.0 1 PMID:16514143 -2.7.7.59 * escherichia coli 550000.0 4 PMID:33596;PMID:6130097 -2.7.7.59 * rhodospirillum rubrum 105000.0 1 PMID:17337583 -2.7.7.6 * anabaena cylindrica 185000.0 10 * -2.7.7.6 * anabaena sp. 171000.0 5 * -2.7.7.6 * clostridioides difficile 140000.0 2 PMID:16352825 -2.7.7.6 * crithidia fasciculata 700000.0 2 PMID:1857206 -2.7.7.6 * escherichia coli 480000.0 5 PMID:18972390;PMID:4400877 -2.7.7.6 * lathyrus oleraceus 620000.0 11 * -2.7.7.6 * leishmania sp. 583000.0 3 PMID:9201702 -2.7.7.6 * microchaete diplosiphon 171000.0 10 * -2.7.7.6 * moniliophthora perniciosa 99000.0 1 PMID:19744344 -2.7.7.6 * pseudomonas aeruginosa 157000.0 4 PMID:3125844 -2.7.7.6 * pseudomonas putida 156000.0 4 PMID:1369075 -2.7.7.6 * rickettsia prowazekii 148000.0 4 PMID:2120186 -2.7.7.6 * saccharolobus solfataricus 40600.0 2 PMID:18235446 -2.7.7.6 * saccharomyces cerevisiae 512000.0 2 PMID:19171965 -2.7.7.6 * schizosaccharomyces pombe 210000.0 11 PMID:8367291 -2.7.7.6 * shewanella violacea 25608.0 2 PMID:19129643 -2.7.7.6 * staphylococcus aureus 151000.0 4 PMID:7695614 -2.7.7.6 * stigmatella aurantiaca 146000.0 3 PMID:1556092 -2.7.7.6 * sulfolobus acidocaldarius 423500.0 14 PMID:1729711;PMID:380989;PMID:8127719 -2.7.7.6 * synechococcus elongatus pcc 7942 = fachb-805 190000.0 9 * -2.7.7.6 * thermotoga maritima 184000.0 4 PMID:8177738 -2.7.7.6 * thermus thermophilus 170000.0 9 PMID:11087385;PMID:2384094 -2.7.7.6 * vectrevirus k1e 100000.0 1 PMID:20596705 -2.7.7.60 * arabidopsis thaliana 29000.0 2 PMID:10841550 -2.7.7.60 * campylobacter jejuni 250000.0 2 PMID:15466439 -2.7.7.60 * escherichia coli 50000.0 6 PMID:10518523;PMID:10841550;PMID:11468415;PMID:12595740;PMID:15649375 -2.7.7.60 * francisella tularensis 25900.0 1 PMID:21694781 -2.7.7.60 * ginkgo biloba 36300.0 1 PMID:16828818 -2.7.7.60 * mycobacterium tuberculosis 52000.0 3 PMID:18047786 -2.7.7.60 * plasmodium vivax 118000.0 1 PMID:29958953 -2.7.7.60 * streptomyces coelicolor 27712.0 1 PMID:11408165 -2.7.7.61 * escherichia coli 20300.0 1 PMID:10924139 -2.7.7.61 * klebsiella pneumoniae 20100.0 1 PMID:11948157 -2.7.7.62 * escherichia coli 34000.0 1 PMID:17693493 -2.7.7.62 * methanocaldococcus jannaschii 43000.0 2 PMID:19489548 -2.7.7.62 * salmonella enterica 20000.0 1 PMID:12195810 -2.7.7.62 * salmonella enterica subsp. enterica serovar typhimurium 49000.0 5 PMID:10529169;PMID:7559521;PMID:9601028 -2.7.7.64 * arabidopsis thaliana 70000.0 4 PMID:17341835;PMID:18768324 -2.7.7.64 * cucumis melo 68000.0 1 PMID:16829585 -2.7.7.64 * giardia duodenalis 50000.0 2 PMID:25316289 -2.7.7.64 * lathyrus oleraceus 67000.0 2 PMID:15326166 -2.7.7.64 * leishmania major 70400.0 4 PMID:19906649 -2.7.7.64 * populus deltoides 77500.0 1 * -2.7.7.64 * thermus caldophilus 45000.0 2 PMID:9889080 -2.7.7.64 * trypanosoma cruzi 67000.0 2 PMID:20482518 -2.7.7.65 * anaplasma phagocytophilum 56000.0 3 PMID:18978058 -2.7.7.65 * azospirillum brasilense 62000.0 1 PMID:26708984 -2.7.7.65 * desulfotalea psychrophila 170000.0 2 PMID:19818878 -2.7.7.65 * escherichia coli 95000.0 3 PMID:19764732 -2.7.7.65 * pseudomonas aeruginosa 85900.0 5 PMID:17586641;PMID:18366254;PMID:25809128 -2.7.7.65 * pseudomonas savastanoi pv. savastanoi 76000.0 1 PMID:25809128 -2.7.7.65 * rhodococcus ruber 565000.0 1 PMID:31195084 -2.7.7.65 * thermotoga maritima 21000.0 1 PMID:19328769 -2.7.7.65 * vibrio cholerae serotype o1 101600.0 4 PMID:28500346 -2.7.7.65 * xanthomonas citri pv. citri 360000.0 2 PMID:25463434 -2.7.7.68 * methanocaldococcus jannaschii 50000.0 2 PMID:18260642 -2.7.7.7 * [bacillus] caldotenax 120000.0 2 * -2.7.7.7 * [bacillus] caldovelox 95000.0 1 PMID:1320608 -2.7.7.7 * african swine fever virus 20000.0 1 PMID:9388236 -2.7.7.7 * archaeoglobus fulgidus 94000.0 1 PMID:11938672;PMID:12733971 -2.7.7.7 * bacillus subtilis 115000.0 1 * -2.7.7.7 * badhamia polycephala 200000.0 1 * -2.7.7.7 * bombyx mori 215000.0 2 PMID:8101841 -2.7.7.7 * bos taurus 200000.0 9 PMID:1846563;PMID:1883203;PMID:2541877;PMID:4853390 -2.7.7.7 * chenopodium album 90000.0 1 PMID:8177736 -2.7.7.7 * coprinopsis cinerea 65000.0 1 PMID:8306825 -2.7.7.7 * crithidia fasciculata 43000.0 2 PMID:1537858 -2.7.7.7 * dictyostelium discoideum 130000.0 1 * -2.7.7.7 * drosophila melanogaster 240000.0 10 PMID:15175013;PMID:1883203 -2.7.7.7 * enterobacteria phage prd1 63000.0 1 PMID:7918621 -2.7.7.7 * escherichia coli 160000.0 13 PMID:4604356;PMID:4605284;PMID:8787781 -2.7.7.7 * escherichia phage t7 96000.0 3 * -2.7.7.7 * euglena gracilis 240000.0 2 * -2.7.7.7 * gallus gallus 180000.0 3 PMID:1883203 -2.7.7.7 * geobacillus kaue 99000.0 1 PMID:21870126 -2.7.7.7 * geobacillus stearothermophilus 95000.0 1 PMID:1320608 -2.7.7.7 * hepatitis b virus 20000.0 2 PMID:8955090 -2.7.7.7 * herpes simplex virus 144000.0 1 * -2.7.7.7 * homo sapiens 280000.0 23 PMID:1556099;PMID:1846563;PMID:1883203;PMID:19853037;PMID:20012583;PMID:20176107 -2.7.7.7 * human immunodeficiency virus 1 172100.0 1 PMID:9499061 -2.7.7.7 * ignicoccus hospitalis 88000.0 1 PMID:24760610 -2.7.7.7 * kitasatospora aureofaciens 172000.0 1 PMID:1536880 -2.7.7.7 * leishmania mexicana 145000.0 1 PMID:1576158 -2.7.7.7 * mammalia 300000.0 6 PMID:1883203 -2.7.7.7 * mesocentrotus franciscanus 168000.0 1 PMID:4859478 -2.7.7.7 * methanosarcina acetivorans 42700.0 1 PMID:20080107 -2.7.7.7 * micrococcus luteus 110000.0 1 * -2.7.7.7 * mus musculus 178000.0 3 PMID:1846563 -2.7.7.7 * mycolicibacterium smegmatis 39146.0 1 PMID:21795801 -2.7.7.7 * mycosarcoma maydis 180000.0 1 * -2.7.7.7 * neurospora crassa 150000.0 2 * -2.7.7.7 * orthopoxvirus vaccinia 150000.0 2 * -2.7.7.7 * oryctolagus cuniculus 122000.0 1 PMID:1846563 -2.7.7.7 * pyrococcus abyssi 140000.0 5 PMID:10348896;PMID:11722585;PMID:23040388 -2.7.7.7 * pyrococcus furiosus 218000.0 4 PMID:26920159;PMID:4605284;PMID:8787781;PMID:9348040 -2.7.7.7 * pyrococcus horikoshii 421000.0 4 PMID:11319225;PMID:21192935 -2.7.7.7 * pyrococcus woesei 90000.0 1 PMID:22347593 -2.7.7.7 * rattus norvegicus 150000.0 4 PMID:7516581;PMID:8137427 -2.7.7.7 * ruellia sp. 75000.0 1 * -2.7.7.7 * saccharolobus solfataricus 110000.0 6 PMID:11713310;PMID:1614858;PMID:19773426;PMID:2113898;PMID:8132506;PMID:8703921;PMID:9783162 -2.7.7.7 * saccharomyces cerevisiae 200000.0 14 PMID:1846563;PMID:1883203;PMID:8380419;PMID:9166764 -2.7.7.7 * salasvirus phi29 66000.0 2 PMID:18379997;PMID:9614939 -2.7.7.7 * streptococcus pneumoniae 99000.0 1 PMID:9764480 -2.7.7.7 * sulfolobus acidocaldarius 109000.0 4 PMID:2492226;PMID:3927262 -2.7.7.7 * sulfophobococcus zilligii 91268.0 2 * -2.7.7.7 * tequatrovirus t4 114000.0 1 PMID:4605411 -2.7.7.7 * tequintavirus t5 96000.0 1 * -2.7.7.7 * tetrahymena pyriformis 130000.0 2 * -2.7.7.7 * thermococcus celer 89789.0 1 PMID:20953664 -2.7.7.7 * thermococcus fumicolans 170000.0 2 PMID:10972190 -2.7.7.7 * thermococcus kodakarensis 90000.0 1 PMID:10348896;PMID:11722585;PMID:23040388 -2.7.7.7 * thermococcus marinus 152400.0 2 PMID:19412677 -2.7.7.7 * thermococcus pacificus 90054.0 2 PMID:10348896;PMID:11722585;PMID:23040388 -2.7.7.7 * thermococcus thioreducens 89980.0 1 PMID:18670731 -2.7.7.7 * thermococcus waiotapuensis 90000.0 1 PMID:10348896;PMID:11722585;PMID:23040388 -2.7.7.7 * thermoplasma acidophilum 88000.0 2 PMID:1320608;PMID:2115439;PMID:2541877 -2.7.7.7 * thermus aquaticus 94000.0 2 PMID:32189018;PMID:8324500 -2.7.7.7 * thermus caldophilus 95000.0 1 PMID:8508785 -2.7.7.7 * thermus thermophilus 85000.0 2 PMID:1320608;PMID:19211662;PMID:2541877 -2.7.7.7 * toxoplasma gondii 150000.0 1 * -2.7.7.7 * trypanosoma brucei 100000.0 2 * -2.7.7.7 * vigna radiata 62000.0 1 PMID:18455498 -2.7.7.7 * xenopus laevis 140000.0 2 PMID:1883203 -2.7.7.70 * escherichia coli 55000.0 1 PMID:12101286 -2.7.7.72 * escherichia coli 53000.0 2 PMID:328503 -2.7.7.72 * geobacter sulfurreducens 98390.0 2 PMID:18952795 -2.7.7.72 * saccharolobus shibatae 242000.0 4 PMID:11090289;PMID:8809016 -2.7.7.73 * escherichia coli 27000.0 1 PMID:16388576 -2.7.7.79 * homo sapiens 165000.0 1 PMID:30917604 -2.7.7.79 * saccharomyces cerevisiae 120000.0 4 PMID:14633974;PMID:1660461 -2.7.7.8 * azotobacter vinelandii 200000.0 1 * -2.7.7.8 * bacillus subtilis 75000.0 1 PMID:19433509 -2.7.7.8 * cucumis sativus 150000.0 2 PMID:16593547 -2.7.7.8 * escherichia coli 365000.0 8 PMID:10215858;PMID:330538 -2.7.7.8 * geobacillus stearothermophilus 51000.0 1 * -2.7.7.8 * homo sapiens 240000.0 5 PMID:18083836;PMID:19509288;PMID:22210891 -2.7.7.8 * kitasatospora aureofaciens 210000.0 2 PMID:1122294 -2.7.7.8 * micrococcus luteus 270000.0 5 PMID:1121422;PMID:7054161 -2.7.7.8 * nicotiana tabacum 150000.0 1 PMID:4429350 -2.7.7.8 * nostoc sp. 240000.0 3 * -2.7.7.8 * rhodospirillum rubrum 160000.0 2 PMID:6766923 -2.7.7.8 * salinivibrio costicola 220000.0 2 PMID:3970947 -2.7.7.8 * spinacia oleracea 600000.0 1 PMID:11680851 -2.7.7.8 * streptomyces antibioticus 81133.0 2 PMID:11080643 -2.7.7.8 * synechococcus sp. 275000.0 2 PMID:7347986 -2.7.7.8 * thermus aquaticus 275000.0 1 PMID:7347986 -2.7.7.8 * thermus thermophilus 190000.0 4 PMID:891551 -2.7.7.80 * escherichia coli 52000.0 1 PMID:11463785 -2.7.7.83 * homo sapiens 120000.0 5 PMID:11707391;PMID:9765219 -2.7.7.84 * homo sapiens 180000.0 3 PMID:17408844;PMID:22709583 -2.7.7.84 * lubomirskia baikalensis 35748.0 2 PMID:17854897 -2.7.7.84 * oryctolagus cuniculus 110000.0 2 * -2.7.7.84 * rattus norvegicus 43000.0 1 PMID:7764002 -2.7.7.84 * tedania ignis 34700.0 1 PMID:24184688 -2.7.7.85 * bacillus subtilis 300000.0 6 PMID:18439896;PMID:24939848 -2.7.7.85 * bacillus thuringiensis 155000.0 5 PMID:23608499;PMID:26441857 -2.7.7.85 * mycolicibacterium smegmatis 334500.0 2 PMID:36660887 -2.7.7.85 * thermotoga maritima 370000.0 4 PMID:18439896;PMID:26014055 -2.7.7.87 * pyrococcus abyssi 200000.0 2 PMID:23258706 -2.7.7.87 * sulfurisphaera tokodaii 38200.0 1 PMID:21538543 -2.7.7.9 * arabidopsis thaliana 53000.0 2 PMID:18395530 -2.7.7.9 * bifidobacterium bifidum 200000.0 3 PMID:24014529;PMID:500588 -2.7.7.9 * bos taurus 500000.0 4 PMID:4436332;PMID:5062946 -2.7.7.9 * dictyostelium discoideum 390000.0 1 * -2.7.7.9 * entamoeba histolytica 45000.0 1 PMID:6304512 -2.7.7.9 * escherichia coli 130000.0 2 PMID:10420655;PMID:8169209 -2.7.7.9 * euglena gracilis 64000.0 1 PMID:30223004 -2.7.7.9 * felis catus 360000.0 2 PMID:6099063 -2.7.7.9 * gallus gallus 57000.0 1 PMID:11736658 -2.7.7.9 * ganoderma lucidum 56830.0 1 PMID:26235043 -2.7.7.9 * giardia duodenalis 50000.0 2 PMID:25316289 -2.7.7.9 * gracilaria chouae 72000.0 1 * -2.7.7.9 * grifola frondosa 53170.0 1 PMID:32561281 -2.7.7.9 * homo sapiens 450000.0 4 PMID:22132858;PMID:23254995;PMID:4433565;PMID:4436332 -2.7.7.9 * hordeum vulgare 51600.0 1 PMID:8666250 -2.7.7.9 * hordeum vulgare subsp. vulgare 54000.0 2 PMID:7764848 -2.7.7.9 * larix gmelinii 53700.0 1 PMID:24408396 -2.7.7.9 * leishmania major 59000.0 2 PMID:16611637 -2.7.7.9 * mus musculus 5000000.0 1 PMID:3009305 -2.7.7.9 * mycobacterium tuberculosis 36000.0 1 PMID:18621545 -2.7.7.9 * neurospora crassa 1600000.0 3 * -2.7.7.9 * nostoc sp. 34000.0 2 PMID:24231376 -2.7.7.9 * oryctolagus cuniculus 430000.0 4 PMID:4436332 -2.7.7.9 * oryza sativa 54000.0 1 * -2.7.7.9 * pseudomonas aeruginosa 130000.0 2 PMID:10420655;PMID:8169209 -2.7.7.9 * rattus norvegicus 450000.0 2 PMID:31853 -2.7.7.9 * saccharina japonica 72000.0 1 * -2.7.7.9 * saccharomyces cerevisiae 55000.0 1 PMID:22132858 -2.7.7.9 * solanum tuberosum 53000.0 6 PMID:12231759;PMID:17996328;PMID:2229031;PMID:2558111 -2.7.7.9 * sphingomonas elodea 140000.0 4 PMID:16085866;PMID:16946483;PMID:17434970 -2.7.7.9 * sphingomonas sp. wg 134000.0 1 PMID:31199955 -2.7.7.9 * triticum aestivum 82000.0 1 PMID:29654825 -2.7.7.9 * trypanosoma brucei 54507.0 1 PMID:20724435 -2.7.7.9 * typha latifolia 55000.0 2 PMID:12231759 -2.7.7.9 * xanthomonas campestris pv. campestris 32000.0 1 PMID:18926872 -2.7.7.91 * streptomyces hygroscopicus subsp. jinggangensis 45000.0 1 PMID:20981366 -2.7.7.92 * mus musculus 66000.0 1 PMID:11479279 -2.7.7.92 * oncorhynchus mykiss 260000.0 2 PMID:11479279 -2.7.7.96 * homo sapiens 40000.0 1 PMID:17261271 -2.7.7.97 * streptomyces antibioticus 45000.0 1 PMID:10212227;PMID:1318300;PMID:8385097 -2.7.7.97 * streptomyces anulatus 45000.0 1 PMID:10212227;PMID:1318300;PMID:8385097 -2.7.7.97 * streptomyces lividans 51500.0 2 PMID:10212227;PMID:1318300;PMID:8385097 -2.7.7.99 * pseudomonas putida 27000.0 1 PMID:25767118 -2.7.8.1 * bos taurus 38000.0 1 PMID:9931448 -2.7.8.1 * homo sapiens 46500.0 2 PMID:17132865 -2.7.8.1 * saccharomyces cerevisiae 44500.0 1 PMID:9370323 -2.7.8.11 * canis lupus familiaris 60000.0 2 PMID:6093865 -2.7.8.11 * homo sapiens 24000.0 1 PMID:9370331 -2.7.8.11 * plasmodium falciparum 23924.0 2 PMID:17223316 -2.7.8.11 * plasmodium knowlesi 23740.0 2 PMID:17223316 -2.7.8.11 * rattus norvegicus 300000.0 6 PMID:18462;PMID:4367970;PMID:9370330;PMID:9370331 -2.7.8.11 * saccharomyces cerevisiae 34000.0 3 PMID:3005284;PMID:6300035;PMID:9370330 -2.7.8.11 * toxoplasma gondii 27800.0 1 PMID:11054108 -2.7.8.11 * zea mays 24000.0 1 PMID:21830089 -2.7.8.12 * bacillus subtilis 90400.0 1 PMID:12637499 -2.7.8.12 * staphylococcus epidermidis 85000.0 1 PMID:10648531 -2.7.8.13 * escherichia coli 45000.0 2 PMID:17640276;PMID:8631795 -2.7.8.13 * staphylococcus aureus 2000000.0 2 PMID:5805290 -2.7.8.15 * aspergillus niger 51400.0 1 PMID:12495819 -2.7.8.15 * bos taurus 360000.0 4 PMID:19519349;PMID:2846531 -2.7.8.15 * cricetulus griseus 67000.0 3 PMID:19519349;PMID:9162053 -2.7.8.15 * glycine max 39000.0 1 PMID:7588788 -2.7.8.15 * homo sapiens 44700.0 1 PMID:19519349 -2.7.8.15 * mus musculus 46470.0 1 PMID:19519349 -2.7.8.15 * rattus norvegicus 79400.0 1 PMID:19519349 -2.7.8.17 * bos taurus 166000.0 3 PMID:8940156 -2.7.8.17 * homo sapiens 1000000.0 11 PMID:1318762;PMID:16507578;PMID:19955174;PMID:21173149;PMID:24550498;PMID:25788519;PMID:3019310 -2.7.8.2 * homo sapiens 46500.0 2 PMID:10893425 -2.7.8.2 * mycoplasmopsis fermentans 31100.0 2 PMID:19219498 -2.7.8.21 * escherichia coli 56000.0 1 PMID:6272307 -2.7.8.23 * oryza sativa 38000.0 1 * -2.7.8.23 * streptomyces hygroscopicus 56000.0 4 PMID:1320191;PMID:2160937 -2.7.8.24 * agrobacterium tumefaciens 400000.0 1 PMID:24931117 -2.7.8.26 * pyrococcus sp. 25285.0 1 * -2.7.8.27 * gallus gallus 48540.0 1 PMID:21647613 -2.7.8.27 * homo sapiens 54000.0 2 PMID:23535273 -2.7.8.28 * methanocaldococcus jannaschii 66700.0 2 PMID:11888293 -2.7.8.29 * cricetulus griseus 55000.0 1 PMID:12912985 -2.7.8.29 * homo sapiens 50000.0 1 PMID:19014349 -2.7.8.29 * mus musculus 50000.0 2 PMID:23071296 -2.7.8.31 * xanthomonas phaseoli pv. manihotis 54300.0 1 * -2.7.8.32 * cryptococcus neoformans 99530.0 2 PMID:19864415 -2.7.8.33 * escherichia coli 40960.0 3 PMID:17237164 -2.7.8.33 * thermotoga maritima 33880.0 3 PMID:18723618 -2.7.8.39 * methanothermobacter thermautotrophicus 20900.0 2 PMID:19740749 -2.7.8.41 * homo sapiens 800000.0 2 PMID:16547353;PMID:29343430 -2.7.8.41 * rattus norvegicus 60000.0 2 PMID:1657995 -2.7.8.41 * saccharomyces cerevisiae 240000.0 3 PMID:9442089 -2.7.8.43 * campylobacter jejuni 36700.0 1 PMID:25286856 -2.7.8.43 * neisseria meningitidis 60000.0 1 PMID:25215579 -2.7.8.44 * bacillus subtilis 47079.0 1 PMID:16150696 -2.7.8.5 * cricetulus griseus 60000.0 1 PMID:11171073 -2.7.8.5 * escherichia coli 200000.0 2 PMID:793612 -2.7.8.5 * schizosaccharomyces pombe 120000.0 2 PMID:9468529 -2.7.8.6 * geobacillus stearothermophilus 72870.0 5 PMID:17237178 -2.7.8.6 * salmonella enterica 29000.0 1 PMID:21856724 -2.7.8.7 * aspergillus fumigatus 79600.0 2 PMID:21195204 -2.7.8.7 * aspergillus nidulans 37700.0 1 PMID:25557478 -2.7.8.7 * dictyostelium discoideum 34000.0 4 PMID:21931666 -2.7.8.7 * escherichia coli 50000.0 8 PMID:16788183;PMID:24292120;PMID:7559576;PMID:9211277 -2.7.8.7 * homo sapiens 35000.0 1 PMID:19933275 -2.7.8.7 * moritella marina 33460.0 2 PMID:16859689 -2.7.8.7 * mycoplasmoides pneumoniae 29000.0 2 PMID:16788183 -2.7.8.7 * pseudomonas aeruginosa 27000.0 1 PMID:12381736 -2.7.8.7 * saccharomyces cerevisiae 21000.0 2 PMID:9712852 -2.7.8.7 * streptomyces coelicolor 28000.0 3 PMID:24292120;PMID:7559576 -2.7.8.7 * streptomyces griseus 60000.0 2 PMID:16895912 -2.7.8.7 * streptomyces pneumoniae 53000.0 7 PMID:10903317 -2.7.8.7 * streptomyces verticillus 31600.0 3 PMID:11451672 -2.7.8.8 * escherichia coli 500000.0 5 PMID:1323044;PMID:187212;PMID:19072541 -2.7.8.8 * homo sapiens 55500.0 2 PMID:22100437 -2.7.9.1 * [clostridium] symbiosum 170000.0 7 PMID:16460017;PMID:20202167;PMID:21883547;PMID:237178;PMID:237180;PMID:6294456;PMID:8311453 -2.7.9.1 * acetobacter aceti 330000.0 3 * -2.7.9.1 * arabidopsis thaliana 94000.0 1 PMID:20202167;PMID:21883547;PMID:237178;PMID:8311453 -2.7.9.1 * brugia malayi 96000.0 1 PMID:18539347 -2.7.9.1 * crithidia sp. 100000.0 1 PMID:9653123 -2.7.9.1 * echinochloa crus-galli 385000.0 1 * -2.7.9.1 * entamoeba histolytica 100000.0 3 PMID:15794763;PMID:24708664;PMID:9507062 -2.7.9.1 * flaveria brownii 96300.0 1 PMID:7766886 -2.7.9.1 * flaveria trinervia 103900.0 1 PMID:2172023 -2.7.9.1 * giardia duodenalis 372000.0 4 PMID:10593172;PMID:8390372 -2.7.9.1 * hoya carnosa 95000.0 1 PMID:27450492 -2.7.9.1 * leishmania sp. 100000.0 1 PMID:9653123 -2.7.9.1 * mesembryanthemum crystallinum 94000.0 1 PMID:20202167;PMID:21883547;PMID:237178;PMID:8311453 -2.7.9.1 * microbispora rosea subsp. aerata 91000.0 1 PMID:19170242 -2.7.9.1 * oryza sativa 96600.0 1 PMID:9744098 -2.7.9.1 * phytomonas sp. 100000.0 1 PMID:9653123 -2.7.9.1 * propionibacterium freudenreichii subsp. shermanii 150000.0 1 PMID:237180 -2.7.9.1 * rhodospirillum rubrum 246800.0 3 PMID:3003027 -2.7.9.1 * solanum lycopersicum 95000.0 1 PMID:27450492 -2.7.9.1 * thermoproteus tenax 250000.0 3 PMID:16573681 -2.7.9.1 * trypanosoma brucei 100000.0 2 PMID:11092947;PMID:9653123 -2.7.9.1 * trypanosoma congolense 100000.0 1 PMID:9653123 -2.7.9.1 * trypanosoma cruzi 200000.0 4 PMID:24060543;PMID:27003459;PMID:9653123 -2.7.9.1 * trypanosoma vivax 100000.0 1 PMID:9653123 -2.7.9.1 * zea mays 387000.0 14 PMID:10683263;PMID:17237188;PMID:20202167;PMID:21414960;PMID:21883547;PMID:237178;PMID:24595619;PMID:27450492;PMID:4719122;PMID:8311453 -2.7.9.2 * escherichia coli 250000.0 5 PMID:1310524;PMID:16880 -2.7.9.2 * pyrococcus furiosus 690000.0 3 PMID:11133966;PMID:16233068 -2.7.9.2 * pyrococcus horikoshii 670000.0 1 PMID:19784642 -2.7.9.2 * saccharolobus solfataricus 89300.0 1 * -2.7.9.2 * thermococcus kodakarensis 87520.0 1 PMID:16879645 -2.7.9.2 * thermoproteus tenax 600000.0 4 PMID:16573681 -2.7.9.3 * aquifex aeolicus 204000.0 3 PMID:18540050 -2.7.9.3 * bos taurus 41768.0 5 PMID:17611817;PMID:17712607 -2.7.9.3 * escherichia coli 37500.0 2 PMID:24719756;PMID:29715549;PMID:9482859 -2.7.9.3 * leishmania major 100000.0 4 PMID:18812192;PMID:23908029 -2.7.9.3 * methanococcus maripaludis 36152.0 1 PMID:19919669 -2.7.9.3 * penaeus monodon 45500.0 1 PMID:21664929 -2.7.9.3 * peptoclostridium acidaminophilum 36000.0 1 PMID:18165360 -2.7.9.3 * trypanosoma brucei 100000.0 3 PMID:18812192 -2.7.9.3 * trypanosoma brucei brucei 45000.0 1 PMID:23908029 -2.7.9.4 * amaranthus hypochondriacus 156105.0 1 PMID:32867090 -2.7.9.4 * amborella trichopoda 146933.0 1 PMID:32867090 -2.7.9.4 * ananas comosus 165093.0 1 PMID:32867090 -2.7.9.4 * arabidopsis thaliana 160000.0 3 PMID:19275898;PMID:24697163;PMID:32867090 -2.7.9.4 * auxenochlorella protothecoides 135517.0 1 PMID:32867090 -2.7.9.4 * brachypodium distachyon 162600.0 1 PMID:32867090 -2.7.9.4 * brassica rapa 144354.0 1 PMID:32867090 -2.7.9.4 * capsella rubella 144939.0 1 PMID:32867090 -2.7.9.4 * capsicum annuum 163598.0 1 PMID:32867090 -2.7.9.4 * carica papaya 165710.0 1 PMID:32867090 -2.7.9.4 * chlamydomonas reinhardtii 154283.0 1 PMID:32867090 -2.7.9.4 * chondrus crispus 150301.0 1 PMID:32867090 -2.7.9.4 * chromochloris zofingiensis 118300.0 1 PMID:32867090 -2.7.9.4 * citrus x clementina 141040.0 1 PMID:32867090 -2.7.9.4 * coffea arabica 165508.0 1 PMID:32867090 -2.7.9.4 * cucumis melo 164902.0 1 PMID:32867090 -2.7.9.4 * dioscorea alata 169131.0 1 PMID:32867090 -2.7.9.4 * fragaria vesca 155592.0 1 PMID:32867090 -2.7.9.4 * glycine max 163761.0 1 PMID:32867090 -2.7.9.4 * gossypium hirsutum 146156.0 1 PMID:32867090 -2.7.9.4 * helianthus annuus 163484.0 1 PMID:32867090 -2.7.9.4 * hordeum vulgare 157590.0 1 PMID:32867090 -2.7.9.4 * lathyrus oleraceus 160000.0 1 PMID:10758490;PMID:11982928 -2.7.9.4 * linum usitatissimum 149512.0 1 PMID:32867090 -2.7.9.4 * malcolmia maritima 144304.0 1 PMID:32867090 -2.7.9.4 * malus domestica 156915.0 1 PMID:32867090 -2.7.9.4 * manihot esculenta 180300.0 2 PMID:32867090 -2.7.9.4 * marchantia polymorpha 156626.0 1 PMID:32867090 -2.7.9.4 * musa acuminata subsp. malaccensis 181353.0 1 PMID:32867090 -2.7.9.4 * myagrum perfoliatum 140157.0 1 PMID:32867090 -2.7.9.4 * nicotiana tabacum 163426.0 1 PMID:32867090 -2.7.9.4 * oryza sativa japonica group 134156.0 1 PMID:32867090 -2.7.9.4 * panicum miliaceum 163391.0 1 PMID:32867090 -2.7.9.4 * phaseolus vulgaris 163484.0 1 PMID:32867090 -2.7.9.4 * porphyra umbilicalis 144770.0 1 PMID:32867090 -2.7.9.4 * ricinus communis 146401.0 1 PMID:32867090 -2.7.9.4 * solanum chacoense 159732.0 1 PMID:32867090 -2.7.9.4 * solanum lycopersicum 163791.0 1 PMID:32867090 -2.7.9.4 * solanum tuberosum 330000.0 5 PMID:10758490;PMID:11982928;PMID:14525539;PMID:32867090 -2.7.9.4 * sorghum bicolor 164264.0 1 PMID:32867090 -2.7.9.4 * sphagnum magellanicum 170633.0 1 PMID:32867090 -2.7.9.4 * spirodela polyrhiza 160000.0 2 PMID:10758490;PMID:11982928;PMID:18643949 -2.7.9.4 * theobroma cacao 140321.0 1 PMID:32867090 -2.7.9.4 * triticum aestivum 154082.0 1 PMID:32867090 -2.7.9.4 * vigna unguiculata 163535.0 1 PMID:32867090 -2.7.9.4 * vitis vinifera 165452.0 1 PMID:32867090 -2.7.9.4 * zea mays 163962.0 1 PMID:32867090 -2.7.9.5 * solanum tuberosum 132270.0 2 * -2.8.1.1 * acinetobacter calcoaceticus 35000.0 2 PMID:3480285;PMID:6931629 -2.8.1.1 * ancylobacter novellus 78000.0 2 * -2.8.1.1 * aquifex aeolicus 65000.0 10 PMID:17697123;PMID:20060433 -2.8.1.1 * azotobacter vinelandii 29000.0 1 PMID:8490572 -2.8.1.1 * bos taurus 37500.0 5 PMID:1627606;PMID:4583640;PMID:5047825;PMID:5135514 -2.8.1.1 * cavia porcellus 37000.0 1 PMID:6286464 -2.8.1.1 * chlorocebus aethiops 37000.0 1 PMID:6586594 -2.8.1.1 * eidolon helvum 36000.0 1 PMID:15469707 -2.8.1.1 * escherichia coli 22500.0 4 PMID:10735872;PMID:11997041;PMID:3553189 -2.8.1.1 * homo sapiens 334000.0 2 PMID:19695240;PMID:20663881 -2.8.1.1 * manihot esculenta 33000.0 3 * -2.8.1.1 * mus musculus 34800.0 2 * -2.8.1.1 * mycobacterium tuberculosis 74000.0 1 PMID:31727914 -2.8.1.1 * oncorhynchus mykiss 34000.0 2 PMID:8535164 -2.8.1.1 * pseudomonas aeruginosa 32000.0 1 PMID:16307778 -2.8.1.1 * rana temporaria 20300.0 2 * -2.8.1.1 * rattus norvegicus 32000.0 1 PMID:6286464 -2.8.1.1 * rhodopseudomonas palustris 16500.0 1 * -2.8.1.1 * staphylococcus aureus 21600.0 1 PMID:25793461 -2.8.1.1 * trametes sanguinea 51700.0 1 * -2.8.1.10 * saccharomyces cerevisiae 34991.0 1 PMID:22031445 -2.8.1.12 * aspergillus nidulans 21600.0 2 PMID:10383438 -2.8.1.12 * escherichia coli 52800.0 4 PMID:11459846 -2.8.1.12 * homo sapiens 20900.0 4 PMID:12732628;PMID:9889283 -2.8.1.12 * mycobacterium tuberculosis 17000.0 2 PMID:25651977 -2.8.1.15 * pyrococcus horikoshii 35600.0 1 PMID:23444054 -2.8.1.16 * methanocaldococcus jannaschii 26000.0 1 PMID:18931440 -2.8.1.2 * arabidopsis thaliana 36000.0 1 PMID:10951223 -2.8.1.2 * bos taurus 33000.0 2 PMID:6948992;PMID:8806051;PMID:8934630;PMID:9749958 -2.8.1.2 * escherichia coli 23800.0 1 PMID:4550801 -2.8.1.2 * homo sapiens 30000.0 2 PMID:23698001;PMID:25336638 -2.8.1.2 * leishmania major 40000.0 1 PMID:12419809 -2.8.1.2 * leishmania mexicana 40000.0 1 PMID:12419809 -2.8.1.2 * mus musculus 66600.0 4 PMID:23146073;PMID:23537657 -2.8.1.2 * mycobacterium tuberculosis 74000.0 1 PMID:31727914 -2.8.1.2 * rana temporaria 30200.0 2 * -2.8.1.2 * rattus norvegicus 66600.0 16 PMID:17130129;PMID:18537713;PMID:23146073;PMID:24611772;PMID:6026243;PMID:6960622;PMID:7608189;PMID:851908;PMID:8806051;PMID:8934630;PMID:9749958 -2.8.1.2 * trichomonas vaginalis 33000.0 2 PMID:19762467 -2.8.1.3 * saccharomyces cerevisiae 17000.0 1 PMID:383018 -2.8.1.5 * nitratidesulfovibrio vulgaris 16300.0 1 * -2.8.1.5 * scenedesmus fuscus 55000.0 4 PMID:24253096 -2.8.1.5 * thermophilic iron-oxidizing bacterium strain ti-1 243000.0 2 * -2.8.1.6 * arabidopsis thaliana 50000.0 3 PMID:12714594;PMID:8819873 -2.8.1.6 * bacillus subtilis 80000.0 2 PMID:12471501;PMID:9211288 -2.8.1.6 * escherichia coli 173900.0 14 PMID:11444982;PMID:12382038;PMID:19821612;PMID:22326745;PMID:8142361;PMID:9211287 -2.8.1.6 * lysinibacillus sphaericus 75000.0 4 PMID:12471501;PMID:8554581;PMID:9211288 -2.8.1.7 * acidithiobacillus ferrooxidans 46000.0 2 PMID:17660944 -2.8.1.7 * arabidopsis thaliana 47000.0 1 PMID:22511606 -2.8.1.7 * azotobacter vinelandii 87500.0 2 PMID:8464885 -2.8.1.7 * bacillus subtilis 113000.0 3 PMID:20822158;PMID:21236255 -2.8.1.7 * escherichia coli 90000.0 3 PMID:23593335;PMID:23682711;PMID:24196966 -2.8.1.7 * haloferax volcanii 110000.0 3 PMID:20226884 -2.8.1.7 * homo sapiens 50000.0 3 PMID:23593335;PMID:23682711;PMID:9885568 -2.8.1.7 * klebsiella pneumoniae 140000.0 1 PMID:10781558 -2.8.1.7 * lentinula edodes 54000.0 1 PMID:26054293 -2.8.1.7 * rattus norvegicus 49720.0 2 PMID:16140891 -2.8.1.7 * ruminococcus flavefaciens 43200.0 2 * -2.8.1.7 * saccharomyces cerevisiae 200000.0 6 PMID:15220327;PMID:16341090;PMID:22928949;PMID:24217246 -2.8.1.7 * streptomyces lividans 45000.0 1 PMID:17469805 -2.8.1.7 * synechocystis sp. 88000.0 4 PMID:11193410;PMID:15379559 -2.8.1.8 * escherichia coli 84600.0 3 PMID:11106496;PMID:1655709 -2.8.1.9 * ammopiptanthus nanus 84850.0 1 PMID:25721201 -2.8.1.9 * arabidopsis thaliana 92600.0 1 PMID:11553608 -2.8.2.1 * canis lupus familiaris 60000.0 1 PMID:6956338 -2.8.2.1 * danio rerio 35000.0 1 PMID:15820212 -2.8.2.1 * drosophila melanogaster 52000.0 7 PMID:18256476 -2.8.2.1 * haliangium ochraceum 40000.0 1 * -2.8.2.1 * homo sapiens 250000.0 9 PMID:19904771;PMID:2327787;PMID:27338799;PMID:3860259;PMID:8117269;PMID:8565785;PMID:9325148 -2.8.2.1 * ictalurus punctatus 41000.0 1 PMID:10775429 -2.8.2.1 * rattus norvegicus 68000.0 8 PMID:23494622;PMID:447677;PMID:6948989;PMID:8530477 -2.8.2.1 * squalius cephalus 35000.0 1 PMID:16962072 -2.8.2.11 * homo sapiens 54000.0 1 PMID:8830034 -2.8.2.11 * mus musculus 110000.0 5 PMID:1429739;PMID:17658888;PMID:19895791 -2.8.2.11 * rattus norvegicus 64000.0 1 PMID:3861135 -2.8.2.14 * cavia porcellus 76000.0 1 PMID:6956371 -2.8.2.14 * heterodontus portusjacksoni 40000.0 1 PMID:7749614 -2.8.2.14 * homo sapiens 68000.0 5 PMID:20102295;PMID:3862362 -2.8.2.14 * macaca mulatta 30000.0 1 PMID:3470420 -2.8.2.14 * mesocricetus auratus 200000.0 3 PMID:6954993 -2.8.2.14 * rattus norvegicus 130000.0 5 PMID:23845;PMID:6954993;PMID:831833 -2.8.2.15 * danio rerio 62000.0 1 PMID:15781253 -2.8.2.15 * homo sapiens 70000.0 12 PMID:11457664;PMID:156557;PMID:21187059;PMID:21913674;PMID:22679001;PMID:23593328;PMID:2764897;PMID:6932974;PMID:8297382 -2.8.2.15 * mus musculus 38400.0 2 PMID:20718863;PMID:9484797 -2.8.2.15 * rattus norvegicus 70000.0 5 PMID:3464463;PMID:6596951;PMID:737567 -2.8.2.16 * synechococcus sp. 58000.0 1 PMID:24414560 -2.8.2.17 * bos taurus 38000.0 1 PMID:3456754 -2.8.2.17 * gallus gallus 160000.0 4 PMID:3092873;PMID:7629189;PMID:8408053 -2.8.2.17 * mus musculus 67000.0 2 PMID:16720579 -2.8.2.18 * bos taurus 62100.0 2 * -2.8.2.18 * meriones sp. 98300.0 1 PMID:2859103 -2.8.2.18 * mesocricetus auratus 105000.0 1 PMID:2859103 -2.8.2.18 * rattus norvegicus 160000.0 7 PMID:485156;PMID:6584367;PMID:737567 -2.8.2.2 * cavia porcellus 135000.0 3 PMID:8226877 -2.8.2.2 * homo sapiens 68000.0 6 PMID:11377982;PMID:12756199;PMID:15618673;PMID:8597484 -2.8.2.2 * mesocricetus auratus 106000.0 2 PMID:3860695 -2.8.2.2 * petromyzon marinus 47000.0 1 PMID:14657197 -2.8.2.2 * rattus norvegicus 180000.0 9 PMID:11162411;PMID:11527219;PMID:16368200;PMID:6173569;PMID:6935986;PMID:8924618 -2.8.2.20 * bos taurus 100000.0 1 PMID:2295314 -2.8.2.20 * caenorhabditis elegans 47000.0 1 PMID:20229090 -2.8.2.20 * homo sapiens 54000.0 6 PMID:16244708;PMID:24909447;PMID:9501187 -2.8.2.20 * mus musculus 42130.0 1 PMID:9501187 -2.8.2.20 * rattus norvegicus 143000.0 3 PMID:1338043;PMID:9015392;PMID:9522174;PMID:9726284 -2.8.2.21 * bos taurus 240000.0 3 PMID:6222956;PMID:6592165 -2.8.2.21 * gallus gallus 66000.0 3 PMID:11469798 -2.8.2.21 * mus musculus 120000.0 1 PMID:24152993 -2.8.2.22 * [clostridium] innocuum 320000.0 2 PMID:12115126 -2.8.2.22 * agathobacter rectalis 75000.0 1 PMID:11320417 -2.8.2.22 * desulfitobacterium hafniense 71400.0 2 * -2.8.2.22 * escherichia coli 128000.0 3 PMID:18565543;PMID:19036922 -2.8.2.22 * eubacterium sp. 315000.0 4 PMID:12115126;PMID:17202651;PMID:3460636 -2.8.2.22 * haemophilus sp. 290000.0 2 PMID:8576095 -2.8.2.22 * klebsiella sp. 160000.0 2 PMID:1491000 -2.8.2.22 * lelliottia amnigena 63880.0 1 PMID:10600454 -2.8.2.22 * streptomyces sp. 58000.0 1 PMID:20157116 -2.8.2.23 * drosophila melanogaster 49825.0 1 PMID:17482450 -2.8.2.23 * mus musculus 37000.0 2 PMID:15060080;PMID:15096036 -2.8.2.24 * arabidopsis thaliana 40500.0 3 PMID:16367753 -2.8.2.24 * brassica juncea 44000.0 1 * -2.8.2.24 * lepidium sativum 31000.0 1 PMID:16667782 -2.8.2.25 * flaveria chlorifolia 35000.0 2 PMID:1309801;PMID:16666908 -2.8.2.26 * flaveria chlorifolia 35000.0 1 PMID:16666908 -2.8.2.27 * flaveria chlorifolia 35000.0 1 PMID:16666908 -2.8.2.28 * flaveria bidentis 35000.0 1 PMID:16668120 -2.8.2.3 * cavia porcellus 60000.0 3 PMID:3475273 -2.8.2.3 * homo sapiens 62000.0 1 PMID:3861769 -2.8.2.3 * mus musculus 37000.0 2 PMID:18725199 -2.8.2.3 * oryctolagus cuniculus 35880.0 1 PMID:9538231 -2.8.2.30 * homo sapiens 39000.0 1 PMID:10608887 -2.8.2.31 * petromyzon marinus 47000.0 1 PMID:14657197 -2.8.2.32 * heterodontus portusjacksoni 80000.0 4 PMID:7749614 -2.8.2.32 * trygonoptera sp. 69000.0 1 * -2.8.2.32 * trygonorrhina fasciata 66000.0 1 * -2.8.2.33 * squid 66000.0 2 PMID:10871629 -2.8.2.34 * homo sapiens 65000.0 1 PMID:1397553 -2.8.2.34 * rattus norvegicus 32500.0 3 PMID:2435165;PMID:2754334;PMID:3464463 -2.8.2.36 * streptomyces toyocaensis 75000.0 1 PMID:16492565 -2.8.2.4 * bos taurus 76000.0 11 PMID:1900200;PMID:19234312;PMID:23384540;PMID:25009209;PMID:4429698;PMID:4473218;PMID:6066295 -2.8.2.4 * cavia porcellus 67000.0 8 PMID:1406700;PMID:2363709;PMID:3162288;PMID:3476161;PMID:7708052;PMID:8070389 -2.8.2.4 * homo sapiens 68000.0 11 PMID:11006110;PMID:19250196;PMID:23384540;PMID:25009209;PMID:3859706;PMID:8187949;PMID:8297382;PMID:9556564 -2.8.2.4 * rattus norvegicus 35300.0 1 PMID:7857871 -2.8.2.5 * rattus norvegicus 50000.0 2 PMID:9891016 -2.8.2.6 * penicillium chrysogenum 90000.0 1 PMID:18095 -2.8.2.8 * rattus norvegicus 97000.0 3 PMID:3422231;PMID:8163470 -2.8.2.9 * euglena gracilis 26000.0 1 PMID:8129730 -2.8.2.9 * rattus norvegicus 61000.0 3 PMID:11123966;PMID:6946725;PMID:6948989;PMID:9111223 -2.8.3.1 * anaerotignum propionicum 224000.0 3 PMID:11784332;PMID:6586495 -2.8.3.1 * cupriavidus necator 228000.0 3 PMID:23250223 -2.8.3.1 * propionibacterium freudenreichii 56000.0 2 PMID:25447642 -2.8.3.12 * acidaminococcus fermentans 275000.0 14 PMID:10409616;PMID:6945182;PMID:7805881;PMID:7957258;PMID:9083111 -2.8.3.13 * homo sapiens 50000.0 1 PMID:23893049 -2.8.3.13 * rattus norvegicus 52000.0 2 PMID:2597704;PMID:6946836 -2.8.3.14 * anaerocolumna aminovalerica 195000.0 4 PMID:2085413 -2.8.3.15 * aromatoleum aromaticum 40000.0 1 PMID:27102732 -2.8.3.15 * thauera aromatica 215000.0 3 PMID:11418570 -2.8.3.16 * acetobacter aceti 99000.0 4 PMID:22374910 -2.8.3.16 * lactobacillus acidophilus 50000.0 1 PMID:17953571 -2.8.3.16 * oxalobacter formigenes 81000.0 4 PMID:15213226;PMID:2361939;PMID:9150242 -2.8.3.17 * clostridium sporogenes 130000.0 4 PMID:10849007;PMID:11967068 -2.8.3.18 * acetobacter aceti 160000.0 2 PMID:18502856 -2.8.3.18 * trichomonas vaginalis 57000.0 1 PMID:18024431 -2.8.3.18 * trypanosoma brucei 53000.0 1 PMID:15326192 -2.8.3.20 * chloroflexus aurantiacus 90000.0 2 PMID:16952935 -2.8.3.21 * proteus sp. (in: enterobacteria) 91100.0 2 PMID:11409545 -2.8.3.22 * chloroflexus aurantiacus 550000.0 3 PMID:16547052 -2.8.3.23 * acetobacterium woodii 130000.0 3 PMID:21131487;PMID:23315745 -2.8.3.24 * clostridioides difficile 86000.0 2 PMID:16957230 -2.8.3.26 * haloarcula hispanica 71000.0 1 PMID:28932214 -2.8.3.3 * pseudomonas putida 170000.0 4 * -2.8.3.5 * helicobacter pylori 26000.0 1 PMID:9325289 -2.8.3.5 * homo sapiens 52000.0 2 PMID:11090426;PMID:11416199;PMID:11756565;PMID:9128180;PMID:9220967 -2.8.3.5 * mus musculus 58000.0 3 PMID:11090426;PMID:11756565;PMID:23423173 -2.8.3.5 * ovis aries 110000.0 3 PMID:708372 -2.8.3.5 * rattus norvegicus 120000.0 10 PMID:11416199;PMID:17685555;PMID:20025965;PMID:4464844;PMID:6950030;PMID:9128180;PMID:9220967 -2.8.3.5 * sus scrofa 915000.0 18 PMID:10985774;PMID:11327867;PMID:11416199;PMID:1730685;PMID:20606260;PMID:4763316;PMID:9128180;PMID:9220967;PMID:943396 -2.8.3.6 * acinetobacter calcoaceticus 108000.0 3 PMID:6780551 -2.8.3.6 * pseudomonas knackmussii 115000.0 3 PMID:11741862 -2.8.3.6 * pseudomonas putida 109000.0 3 PMID:6780551 -2.8.3.9 * clostridium sp. 108000.0 4 PMID:624727 -2.8.3.9 * escherichia coli 99000.0 6 PMID:1103739;PMID:1103741 -2.8.4.1 * methanobrevibacter ruminantium 59800.0 3 PMID:25483006 -2.8.4.1 * methanocaldococcus jannaschii 300000.0 1 PMID:1332856;PMID:1657649;PMID:17725644;PMID:2504147;PMID:2506016;PMID:3122735;PMID:8223602;PMID:9030728;PMID:9192720;PMID:9367957 -2.8.4.1 * methanococcus maripaludis 65000.0 3 PMID:23533332 -2.8.4.1 * methanococcus voltae 300000.0 1 PMID:1332856;PMID:1657649;PMID:17725644;PMID:2504147;PMID:2506016;PMID:3122735;PMID:8223602;PMID:9030728;PMID:9192720;PMID:9367957 -2.8.4.1 * methanoculleus thermophilus 300000.0 1 PMID:1332856;PMID:1657649;PMID:17725644;PMID:2504147;PMID:2506016;PMID:3122735;PMID:8223602;PMID:9030728;PMID:9192720;PMID:9367957 -2.8.4.1 * methanopyrus kandleri 300000.0 1 PMID:1332856;PMID:1657649;PMID:17725644;PMID:2504147;PMID:2506016;PMID:3122735;PMID:8223602;PMID:9030728;PMID:9192720;PMID:9367957 -2.8.4.1 * methanosarcina barkeri 300000.0 1 PMID:1332856;PMID:1657649;PMID:17725644;PMID:2504147;PMID:2506016;PMID:3122735;PMID:8223602;PMID:9030728;PMID:9192720;PMID:9367957 -2.8.4.1 * methanosarcina mazei 65000.0 6 PMID:23533332 -2.8.4.1 * methanosarcina thermophila 144000.0 6 PMID:2013570 -2.8.4.1 * methanothermobacter marburgensis 300000.0 5 PMID:1332856;PMID:1657649;PMID:17725644;PMID:23533332;PMID:2504147;PMID:2506016;PMID:25691570;PMID:3122735;PMID:8223602;PMID:9030728;PMID:9192720;PMID:9367957 -2.8.4.1 * methanothermobacter thermautotrophicus 300000.0 5 PMID:2506016;PMID:3350018 -2.8.4.1 * methanothermobacter wolfeii 65000.0 3 PMID:23533332 -2.8.4.1 * methanothrix soehngenii 280000.0 4 PMID:22121022 -2.8.4.1 * uncultured archaeon 280000.0 1 PMID:22121022 -2.8.4.3 * escherichia coli 60000.0 2 PMID:11882645 -2.8.4.3 * thermotoga maritima 50710.0 2 PMID:12766153 -2.8.4.4 * escherichia coli 49582.0 1 PMID:19736993 -2.8.4.5 * bacillus subtilis 51658.0 2 PMID:20584901 -2.8.5.2 * allochromatium vinosum 40000.0 1 PMID:16995898 -2.9.1.1 * escherichia coli 600000.0 3 PMID:1839607;PMID:2007584;PMID:23266652 -2.9.1.1 * homo sapiens 48000.0 1 PMID:17916946 -2.9.1.1 * mus musculus 49000.0 3 PMID:17916946;PMID:18093968 -2.9.1.1 * peptoclostridium acidaminophilum 52500.0 1 PMID:11041351 -3.1.1.1 * acinetobacter lwoffii 45000.0 1 PMID:12000989 -3.1.1.1 * aeropyrum pernix 63030.0 1 PMID:21084296 -3.1.1.1 * alicyclobacillus acidocaldarius 37500.0 2 PMID:8181479 -3.1.1.1 * alicyclobacillus tolerans 58000.0 2 PMID:23801110;PMID:3597342 -3.1.1.1 * alopecurus myosuroides 41000.0 2 PMID:15341632;PMID:21315388;PMID:7764506 -3.1.1.1 * anoxybacillus sp. 26000.0 1 PMID:21782026 -3.1.1.1 * arabidopsis thaliana 36600.0 1 PMID:17519238 -3.1.1.1 * archaeoglobus fulgidus 52800.0 6 PMID:10620337;PMID:16086253;PMID:18337701 -3.1.1.1 * arthrobacter globiformis 94000.0 2 * -3.1.1.1 * aspergillus nidulans 37000.0 1 PMID:18224318 -3.1.1.1 * aspergillus nomiae 60000.0 1 PMID:12799010;PMID:3651439;PMID:6208846 -3.1.1.1 * bacillus sp. (in: firmicutes) 53000.0 1 PMID:11178722 -3.1.1.1 * bacillus subtilis 60000.0 5 PMID:16269247;PMID:16621096;PMID:18163883 -3.1.1.1 * bacillus velezensis 64000.0 1 PMID:31761671;PMID:8105781 -3.1.1.1 * bombyx mori 144500.0 2 * -3.1.1.1 * brevundimonas sp. qpt-2 50000.0 1 PMID:7764864 -3.1.1.1 * burkholderia gladioli 32000.0 1 PMID:11152069 -3.1.1.1 * caenorhabditis elegans 60000.0 1 PMID:12799010;PMID:3651439;PMID:6208846 -3.1.1.1 * caldanaerobacter subterraneus subsp. tengcongensis 43000.0 1 PMID:14514051 -3.1.1.1 * cavia porcellus 57100.0 2 PMID:6704404 -3.1.1.1 * culex quinquefasciatus 67200.0 3 PMID:11554734;PMID:1664383 -3.1.1.1 * culex sp. 62000.0 1 * -3.1.1.1 * enterobacter cloacae 54620.0 1 PMID:12556461 -3.1.1.1 * equus caballus 72900.0 2 PMID:3196030 -3.1.1.1 * escherichia coli 57000.0 2 PMID:12732651;PMID:6380369 -3.1.1.1 * ferroplasma acidiphilum 36000.0 3 PMID:16478448 -3.1.1.1 * galeocerdo cuvier 80000.0 1 PMID:1276972 -3.1.1.1 * gallus gallus 67000.0 1 PMID:1139397 -3.1.1.1 * geobacillus stearothermophilus 55000.0 7 PMID:15033540;PMID:7576531 -3.1.1.1 * geobacillus thermodenitrificans 30000.0 1 PMID:20587647 -3.1.1.1 * haloarcula marismortui 50000.0 1 PMID:19759821 -3.1.1.1 * heyndrickxia coagulans 27528.0 1 PMID:15902466 -3.1.1.1 * homo sapiens 340000.0 20 PMID:1248462;PMID:15100172;PMID:18259949;PMID:18762277;PMID:22442219;PMID:2246262;PMID:3341748;PMID:3369858;PMID:4200176;PMID:4216303;PMID:6417119;PMID:718955;PMID:7406498;PMID:7980644;PMID:857894 -3.1.1.1 * klebsiella sp. 73500.0 3 PMID:16448191 -3.1.1.1 * lacticaseibacillus casei 67500.0 4 PMID:12741535;PMID:15184114 -3.1.1.1 * lactobacillus delbrueckii subsp. lactis 63000.0 2 PMID:12741535 -3.1.1.1 * malus domestica 40000.0 2 PMID:15341632;PMID:21315388 -3.1.1.1 * microbacterium sp. 600000.0 2 PMID:11814667 -3.1.1.1 * micrococcus sp. 60000.0 2 PMID:15713880 -3.1.1.1 * mus musculus 184000.0 6 PMID:28771;PMID:6772441;PMID:6788549;PMID:7160378 -3.1.1.1 * mycobacterium tuberculosis 54000.0 2 PMID:15373841;PMID:17428787 -3.1.1.1 * niallia circulans 95000.0 2 PMID:10968629 -3.1.1.1 * oryctolagus cuniculus 209000.0 5 PMID:23801110;PMID:3597342;PMID:7391075 -3.1.1.1 * oryzaephilus surinamensis 120000.0 2 * -3.1.1.1 * ovis aries 182000.0 2 PMID:8759299 -3.1.1.1 * paenarthrobacter nitroguajacolicus 95000.0 2 PMID:17294326 -3.1.1.1 * pseudomonas aeruginosa 66000.0 5 PMID:10559163;PMID:15717224;PMID:20850500 -3.1.1.1 * pseudomonas aeruginosa pao1 24000.0 2 PMID:15717224 -3.1.1.1 * pseudomonas fluorescens 45000.0 3 PMID:12729729;PMID:15341632;PMID:7764506 -3.1.1.1 * pseudomonas putida 33000.0 1 PMID:16321951 -3.1.1.1 * pseudomonas sp. 300000.0 4 PMID:12880765;PMID:7764864 -3.1.1.1 * pyrobaculum calidifontis 98000.0 3 PMID:12147492 -3.1.1.1 * pyrobaculum sp. 21130.0 1 PMID:25250909 -3.1.1.1 * rattus norvegicus 195000.0 18 PMID:12799010;PMID:15767260;PMID:31761671;PMID:3651439;PMID:4200176;PMID:4216303;PMID:4828316;PMID:6208846;PMID:7074137;PMID:738990;PMID:8105781;PMID:870055;PMID:9013810 -3.1.1.1 * reticulitermes flavipes 69000.0 4 PMID:11267909 -3.1.1.1 * rhizobium viscosum 16700.0 1 * -3.1.1.1 * saccharolobus islandicus 67000.0 2 PMID:21847512 -3.1.1.1 * saccharolobus shibatae 90000.0 6 PMID:16233734 -3.1.1.1 * saccharolobus solfataricus 125000.0 16 PMID:11210525;PMID:11867217;PMID:15564667;PMID:16574328;PMID:20361232;PMID:20386955;PMID:3128284 -3.1.1.1 * serratia sp. (in: enterobacteria) 28300.0 1 PMID:19307763 -3.1.1.1 * sesamia nonagrioides 64240.0 1 PMID:21549123 -3.1.1.1 * spodoptera littoralis 61000.0 2 PMID:21124773 -3.1.1.1 * sulfolobus acidocaldarius 117000.0 2 PMID:11867217;PMID:3128284 -3.1.1.1 * sulfurisphaera tokodaii 37400.0 4 PMID:15212797 -3.1.1.1 * sus scrofa 206000.0 8 PMID:15100172;PMID:16960735;PMID:18273909;PMID:22442219;PMID:7406498 -3.1.1.1 * thalassobacillus sp. 49000.0 2 * -3.1.1.1 * thermotoga maritima 40000.0 2 PMID:17106678 -3.1.1.1 * thermus thermophilus 71800.0 3 * -3.1.1.1 * tribolium castaneum 62000.0 2 PMID:12213253 -3.1.1.1 * trichosporon sp. 40000.0 1 PMID:15341632;PMID:21315388 -3.1.1.1 * triticum aestivum 38000.0 2 PMID:6468391 -3.1.1.1 * uncultured bacterium 216000.0 2 PMID:21908637;PMID:29453256 -3.1.1.1 * unidentified 260000.0 3 PMID:16672512 -3.1.1.1 * unidentified soil organism 260000.0 3 PMID:16672512 -3.1.1.10 * oryctolagus cuniculus 61000.0 2 PMID:4435736 -3.1.1.10 * pseudomonas putida 57800.0 2 PMID:3828356 -3.1.1.101 * bacterium hr29 27500.0 1 PMID:33375975 -3.1.1.101 * marinactinospora thermotolerans 34000.0 1 PMID:35557867 -3.1.1.101 * piscinibacter sakaiensis 30247.0 2 PMID:32506284;PMID:36811288 -3.1.1.103 * staphylococcus aureus 43048.0 1 PMID:17925392 -3.1.1.108 * escherichia coli 43000.0 1 PMID:1534808 -3.1.1.108 * geobacillus thermodenitrificans 26000.0 1 PMID:31053933 -3.1.1.11 * actinidia chinensis 50000.0 1 PMID:15675822 -3.1.1.11 * actinidia deliciosa 50000.0 2 PMID:17932919 -3.1.1.11 * agroathelia rolfsii 37000.0 1 PMID:15675822 -3.1.1.11 * arabidopsis thaliana 37000.0 3 PMID:18222123;PMID:18936961;PMID:21692803 -3.1.1.11 * aspergillus aculeatus 41000.0 3 * -3.1.1.11 * aspergillus flavus 40000.0 1 PMID:15951488;PMID:24766423 -3.1.1.11 * aspergillus japonicus 47000.0 3 PMID:12882638 -3.1.1.11 * aspergillus niger 45000.0 1 PMID:22806239 -3.1.1.11 * aspergillus oryzae 34000.0 2 PMID:10052131 -3.1.1.11 * aspergillus pseudoglaucus 141300.0 1 * -3.1.1.11 * capsicum annuum 37000.0 2 PMID:15373415 -3.1.1.11 * carica papaya 53000.0 1 * -3.1.1.11 * citrus bergamia 42000.0 1 PMID:26047267 -3.1.1.11 * citrus nobilis 37000.0 1 PMID:15675822 -3.1.1.11 * citrus sinensis 53000.0 15 PMID:12033828;PMID:12643675;PMID:15769165;PMID:24328246 -3.1.1.11 * clostridium multifermentans 400000.0 1 * -3.1.1.11 * datura inoxia 33000.0 1 PMID:23887498 -3.1.1.11 * datura metel 33000.0 1 PMID:23887498 -3.1.1.11 * datura stramonium 33000.0 1 PMID:23887498 -3.1.1.11 * daucus carota 33000.0 2 PMID:11943159;PMID:11964128 -3.1.1.11 * diospyros kaki 37000.0 1 PMID:15675822 -3.1.1.11 * ficus pumila var. awkeotsang 45000.0 3 PMID:11982420;PMID:15998123 -3.1.1.11 * fragaria x ananassa 43000.0 2 PMID:11992533 -3.1.1.11 * fusarium oxysporum 35000.0 1 * -3.1.1.11 * lathyrus oleraceus 65570.0 1 PMID:23839307 -3.1.1.11 * linum usitatissimum 110000.0 8 PMID:22301970;PMID:22512653 -3.1.1.11 * malpighia glabra 25100.0 2 * -3.1.1.11 * malus sp. 28000.0 1 * -3.1.1.11 * nicotiana tabacum 158000.0 3 PMID:11882942;PMID:15951488;PMID:24766423 -3.1.1.11 * olea europaea 40000.0 3 PMID:20491902 -3.1.1.11 * penicillium oxalicum 55000.0 2 PMID:24584459 -3.1.1.11 * phaseolus vulgaris 46000.0 4 * -3.1.1.11 * phytophthora capsici 38200.0 9 PMID:21259289 -3.1.1.11 * phytophthora infestans 45000.0 3 PMID:16663990 -3.1.1.11 * psidium guajava 99000.0 2 PMID:18608560 -3.1.1.11 * salsola kali 40000.0 2 PMID:17581207 -3.1.1.11 * sitophilus oryzae 38000.0 1 * -3.1.1.11 * solanum lycopersicum 43200.0 6 PMID:12153307;PMID:22301970;PMID:22512653;PMID:7764629 -3.1.1.11 * sphenophorus levis 50000.0 1 PMID:24598920 -3.1.1.113 * pseudomonas putida 36000.0 1 * -3.1.1.116 * homo sapiens 160000.0 1 PMID:27115711 -3.1.1.117 * apiospora arundinis 40000.0 1 PMID:29051046 -3.1.1.117 * ascobolus immersus 47600.0 1 PMID:29051046 -3.1.1.117 * aspergillus fumigatus 44000.0 1 PMID:29332217 -3.1.1.117 * botryosphaeria dothidea 39000.0 1 PMID:29051046 -3.1.1.117 * dichomitus squalens 46700.0 2 PMID:29051046 -3.1.1.117 * hypholoma sublateritium 47400.0 1 PMID:29051046 -3.1.1.117 * neurospora crassa 41300.0 1 PMID:27600355 -3.1.1.117 * parastagonospora nodorum 39500.0 1 PMID:29051046 -3.1.1.117 * penicillium rubens 40200.0 1 PMID:29051046 -3.1.1.117 * phanerochaete carnosa 42500.0 1 PMID:29051046 -3.1.1.117 * piromyces sp. e2 40600.0 1 PMID:29051046 -3.1.1.117 * plenodomus lingam 41600.0 1 PMID:29051046 -3.1.1.117 * podospora anserina 49200.0 2 PMID:29051046 -3.1.1.117 * schizophyllum commune 40200.0 1 PMID:29051046 -3.1.1.117 * serendipita indica 47900.0 1 PMID:29051046 -3.1.1.117 * stereum hirsutum 47200.0 1 PMID:29051046 -3.1.1.117 * thermothelomyces thermophilus 40300.0 2 PMID:19459957;PMID:29051046 -3.1.1.117 * trichoderma reesei 60000.0 3 PMID:17678650;PMID:26712478;PMID:29051046 -3.1.1.124 * aspergillus niger 200000.0 1 PMID:28183264 -3.1.1.13 * acinetobacter sp. 6500.0 1 PMID:20473956 -3.1.1.13 * bos taurus 84000.0 4 PMID:10220579;PMID:20822795;PMID:6849967;PMID:7297682;PMID:7370289 -3.1.1.13 * burkholderia cepacia 37000.0 1 PMID:16463077 -3.1.1.13 * homo sapiens 106000.0 6 PMID:10220579;PMID:11230747;PMID:16131527;PMID:19592704;PMID:20947831 -3.1.1.13 * limtongozyma cylindracea 63000.0 1 PMID:2039758 -3.1.1.13 * mus musculus 106000.0 3 PMID:11230747;PMID:21467808;PMID:24868095 -3.1.1.13 * ophiostoma piceae 58200.0 2 PMID:12479402;PMID:19281875 -3.1.1.13 * oryctolagus cuniculus 66000.0 3 PMID:6520114;PMID:7788563 -3.1.1.13 * pseudomonas aeruginosa 58000.0 2 PMID:12506971 -3.1.1.13 * rattus norvegicus 106000.0 1 PMID:11230747 -3.1.1.13 * rattus sp. 420000.0 11 PMID:10220579;PMID:1422214;PMID:5072699;PMID:6429131;PMID:7278675;PMID:7357021;PMID:7370289;PMID:8463327 -3.1.1.13 * saccharomyces cerevisiae 70000.0 5 PMID:15632184;PMID:15713625;PMID:7026545 -3.1.1.13 * streptomyces avermitilis 120000.0 2 PMID:17161031 -3.1.1.13 * streptomyces griseus 153000.0 2 PMID:17161031 -3.1.1.13 * streptomyces sp. 163000.0 2 PMID:16503286 -3.1.1.13 * sus scrofa 83000.0 6 PMID:12831;PMID:20822795;PMID:3828371;PMID:4337425;PMID:6639954 -3.1.1.13 * trichoderma sp. 58200.0 3 PMID:18499049 -3.1.1.14 * arabidopsis thaliana 35000.0 1 * -3.1.1.14 * auxenochlorella protothecoides 38000.0 1 PMID:7446992 -3.1.1.14 * brassica oleracea 78000.0 6 PMID:20681655 -3.1.1.14 * chenopodium album 46000.0 2 * -3.1.1.14 * chlorella regularis 130000.0 2 * -3.1.1.14 * citrus unshiu 110000.0 2 * -3.1.1.14 * citrus x limon 158000.0 4 PMID:18633118;PMID:21071427 -3.1.1.14 * ginkgo biloba 38000.0 3 PMID:18998412 -3.1.1.14 * phaeodactylum tricornutum 46000.0 3 * -3.1.1.14 * phaseolus vulgaris 30000.0 1 PMID:24414364 -3.1.1.14 * prunus cerasus 100000.0 2 PMID:23894730 -3.1.1.14 * prunus domestica 100000.0 2 PMID:23894730 -3.1.1.14 * prunus padus 90000.0 2 PMID:23894730 -3.1.1.14 * secale cereale 39000.0 1 PMID:6819291 -3.1.1.14 * triticum aestivum 33880.0 2 PMID:15913540;PMID:21591176 -3.1.1.15 * haloferax volcanii 28000.0 1 PMID:28854683 -3.1.1.17 * bos taurus 233000.0 2 PMID:35106 -3.1.1.17 * euglena gracilis 34000.0 1 PMID:18782759 -3.1.1.17 * gluconobacter oxydans 120000.0 2 PMID:19129636 -3.1.1.17 * homo sapiens 45000.0 2 PMID:19103263;PMID:23349732 -3.1.1.17 * mus musculus 34000.0 1 PMID:23349732 -3.1.1.17 * pseudomonas aeruginosa 40000.0 1 PMID:18832304 -3.1.1.17 * sus scrofa 223000.0 2 PMID:718684 -3.1.1.17 * zymomonas mobilis 90000.0 5 PMID:1482681;PMID:3745122 -3.1.1.2 * archaeoglobus fulgidus 27500.0 1 PMID:18337701 -3.1.1.2 * bos taurus 440000.0 3 PMID:12946270;PMID:15805725;PMID:1673382;PMID:1673383;PMID:175783;PMID:24907040 -3.1.1.2 * brevundimonas diminuta 82000.0 2 PMID:10421461;PMID:15790580;PMID:19103263;PMID:19902382;PMID:21123122;PMID:8634243 -3.1.1.2 * cavia porcellus 180000.0 2 PMID:5047702 -3.1.1.2 * diabrotica virgifera virgifera 65600.0 1 * -3.1.1.2 * gluconobacter oxydans 76800.0 2 PMID:23003572 -3.1.1.2 * homo sapiens 127500.0 16 PMID:10421461;PMID:11369803;PMID:12946270;PMID:15772423;PMID:16139510;PMID:1673382;PMID:1673383;PMID:18355454;PMID:18952040;PMID:19103263;PMID:19902382;PMID:20176005;PMID:21123122;PMID:24907040;PMID:25107406;PMID:8634243 -3.1.1.2 * lacticaseibacillus casei 216500.0 2 PMID:12939078 -3.1.1.2 * lacticaseibacillus rhamnosus 151600.0 1 PMID:34881159 -3.1.1.2 * lactobacillus helveticus 25100.0 2 PMID:10792515 -3.1.1.2 * mus musculus 52000.0 1 PMID:18486363 -3.1.1.2 * oryctolagus cuniculus 42300.0 2 PMID:8565784 -3.1.1.2 * petroselinum crispum 35000.0 2 PMID:6870256 -3.1.1.2 * rattus norvegicus 45000.0 2 PMID:10421461;PMID:12946270;PMID:1673382;PMID:1673383;PMID:19103263;PMID:19902382;PMID:21123122;PMID:24907040;PMID:8634243 -3.1.1.2 * saccharolobus islandicus 80000.0 1 PMID:23071703 -3.1.1.2 * saccharolobus solfataricus 37000.0 3 PMID:18931117 -3.1.1.2 * saccharomyces cerevisiae 84000.0 2 * -3.1.1.2 * sinorhizobium meliloti 24315.0 2 PMID:21543864 -3.1.1.2 * sinorhizobium meliloti 1021 69550.0 2 PMID:20060410 -3.1.1.2 * triticum aestivum 45000.0 1 * -3.1.1.2 * uncultured organism 24000.0 2 PMID:21533577 -3.1.1.2 * vulcanisaeta moutnovskia 82000.0 2 PMID:24858677 -3.1.1.20 * [candida] sp. 250000.0 2 * -3.1.1.20 * aspergillus awamori 230000.0 5 PMID:19844665;PMID:21030825;PMID:21279470 -3.1.1.20 * aspergillus flavus 194000.0 2 * -3.1.1.20 * aspergillus fumigatus 60340.0 1 PMID:29868308 -3.1.1.20 * aspergillus nidulans 302000.0 4 * -3.1.1.20 * aspergillus niger 310000.0 13 PMID:14523126;PMID:14625895;PMID:14683525;PMID:19809257;PMID:21503777 -3.1.1.20 * aspergillus ochraceus 85000.0 1 * -3.1.1.20 * aspergillus oryzae 310000.0 14 PMID:15249037;PMID:27373426;PMID:8917102 -3.1.1.20 * aspergillus phoenicis 218000.0 1 * -3.1.1.20 * aspergillus sp. 102000.0 2 PMID:16463321 -3.1.1.20 * bacillus subtilis 52000.0 1 PMID:24613317 -3.1.1.20 * blastobotrys adeninivorans 320000.0 5 PMID:19387973 -3.1.1.20 * enterobacter cloacae 31000.0 1 PMID:24613317 -3.1.1.20 * enterobacter sp. 90000.0 2 PMID:24613317 -3.1.1.20 * escherichia coli 55000.0 1 PMID:24613317 -3.1.1.20 * fusarium subglutinans 150000.0 1 * -3.1.1.20 * hypocreales sp. 155000.0 4 PMID:17786433 -3.1.1.20 * klebsiella pneumoniae 46500.0 1 PMID:24613317 -3.1.1.20 * kluyveromyces marxianus 66620.0 1 PMID:29055707 -3.1.1.20 * lactiplantibacillus paraplantarum 50000.0 1 PMID:24708557 -3.1.1.20 * lactiplantibacillus pentosus 50000.0 1 PMID:24708557 -3.1.1.20 * lactiplantibacillus plantarum 67000.0 7 PMID:18653299;PMID:23545659;PMID:24610854;PMID:24613317;PMID:24708557 -3.1.1.20 * paecilomyces variotii 149800.0 4 PMID:16133325 -3.1.1.20 * penicillium chrysogenum 97000.0 2 PMID:24350277 -3.1.1.20 * quercus robur 300000.0 4 * -3.1.1.20 * rhodococcus sp. (in: high g+c gram-positive bacteria) 60000.0 1 PMID:24613317 -3.1.1.20 * selenomonas ruminantium 59000.0 1 PMID:16887543;PMID:24613317 -3.1.1.20 * streptococcus gallolyticus 52980.0 1 PMID:24577784 -3.1.1.20 * streptomyces sp. 180000.0 1 PMID:29291146 -3.1.1.20 * talaromyces variabilis 310000.0 4 PMID:17570660 -3.1.1.20 * trametes elegans 163000.0 3 * -3.1.1.20 * uncultured bacterium 55000.0 1 PMID:21388130 -3.1.1.22 * alcaligenes faecalis 74000.0 2 PMID:6626560 -3.1.1.22 * cupriavidus necator 78000.0 1 PMID:16233278 -3.1.1.22 * paracoccus denitrificans 120000.0 4 PMID:11814660;PMID:24271169 -3.1.1.22 * paucimonas lemoignei 32000.0 1 PMID:17964488 -3.1.1.22 * pseudomonas sp. 72880.0 2 PMID:8981982 -3.1.1.22 * zoogloea ramigera 30000.0 2 PMID:7285912 -3.1.1.23 * bacillus sp. (in: firmicutes) 28000.0 2 PMID:11226879 -3.1.1.23 * bacillus subtilis 20500.0 2 PMID:11029590 -3.1.1.23 * gallus gallus 45000.0 1 PMID:7278672 -3.1.1.23 * homo sapiens 70000.0 9 PMID:18452279;PMID:18452392;PMID:18721756;PMID:23795559;PMID:25140003;PMID:8526865 -3.1.1.23 * mortierella alliacea 11000.0 2 PMID:20932946 -3.1.1.23 * mus musculus 33218.0 2 PMID:15371507;PMID:9341166 -3.1.1.23 * mycobacterium tuberculosis 30223.0 1 PMID:17784850 -3.1.1.23 * mycolicibacterium smegmatis 30000.0 2 PMID:20601476 -3.1.1.23 * pseudomonas sp. 59000.0 1 PMID:16232941 -3.1.1.23 * rattus norvegicus 63000.0 11 PMID:12136125;PMID:12505697;PMID:15272052;PMID:889853 -3.1.1.24 * acinetobacter calcoaceticus 33000.0 3 PMID:1158871;PMID:7391022;PMID:7391023 -3.1.1.24 * paraburkholderia xenovorans 57600.0 1 PMID:21237173 -3.1.1.24 * pseudomonas putida 33000.0 3 PMID:7391022;PMID:7391023 -3.1.1.24 * rhodococcus opacus 42230.0 2 PMID:9495744 -3.1.1.25 * agrobacterium tumefaciens 62000.0 2 PMID:10923798 -3.1.1.25 * bacillus thuringiensis serovar kurstaki 29000.0 1 PMID:15895999 -3.1.1.25 * fusarium proliferatum 68000.0 2 PMID:17530243;PMID:19876606 -3.1.1.25 * homo sapiens 95600.0 10 PMID:15772423;PMID:16139510;PMID:19103263;PMID:21123122;PMID:25107406 -3.1.1.25 * rattus norvegicus 43000.0 1 PMID:12946270 -3.1.1.25 * saccharolobus islandicus 80000.0 1 PMID:23071703 -3.1.1.25 * vulcanisaeta moutnovskia 82000.0 6 PMID:24192357;PMID:24858677 -3.1.1.26 * canis lupus familiaris 50000.0 1 PMID:18328758 -3.1.1.26 * cavia porcellus 50000.0 1 PMID:18328758 -3.1.1.26 * equus caballus 50000.0 1 PMID:18328758 -3.1.1.26 * felis silvestris 50000.0 1 PMID:18328758 -3.1.1.26 * gracilaria vermiculophylla 40000.0 2 * -3.1.1.26 * homo sapiens 52924.0 8 PMID:15450178;PMID:18328758;PMID:18702514;PMID:22835523 -3.1.1.26 * myocastor coypus 50000.0 1 PMID:18328758 -3.1.1.26 * oryctolagus cuniculus 50000.0 1 PMID:18328758 -3.1.1.26 * oryza sativa 40000.0 1 * -3.1.1.26 * parachlorella kessleri 242000.0 1 PMID:29299622 -3.1.1.26 * phaseolus coccineus 110000.0 1 PMID:5784904 -3.1.1.26 * phaseolus vulgaris 90000.0 1 * -3.1.1.26 * rattus norvegicus 50000.0 2 PMID:18328758 -3.1.1.26 * solanum tuberosum 110000.0 2 PMID:236765;PMID:454635 -3.1.1.26 * sus scrofa 50000.0 1 PMID:18328758 -3.1.1.26 * vigna unguiculata 80000.0 4 PMID:11240125;PMID:7948009 -3.1.1.27 * mesorhizobium loti 59000.0 4 PMID:16226926;PMID:19724124 -3.1.1.27 * pseudomonas sp. 54000.0 2 PMID:3771565 -3.1.1.28 * alcaligenes sp. 67000.0 1 PMID:8222264 -3.1.1.28 * rattus norvegicus 60000.0 1 PMID:6208846 -3.1.1.29 * artemia sp. 55000.0 1 * -3.1.1.29 * fusarium culmorum 46000.0 1 * -3.1.1.29 * homo sapiens 23000.0 1 PMID:20186120 -3.1.1.29 * methanocaldococcus jannaschii 13500.0 2 PMID:12475929 -3.1.1.29 * mycobacterium tuberculosis 21978.0 4 PMID:16946478;PMID:17516842;PMID:18342886 -3.1.1.29 * mycolicibacterium smegmatis 21000.0 1 PMID:22509481 -3.1.1.29 * pseudomonas aeruginosa 24000.0 1 PMID:25101795 -3.1.1.29 * pseudomonas syringae pv. tomato 12700.0 1 PMID:18247350 -3.1.1.29 * pyrococcus horikoshii 25300.0 3 PMID:12799450;PMID:17327676;PMID:18391411 -3.1.1.29 * saccharolobus solfataricus 25000.0 5 PMID:12799450;PMID:17327676 -3.1.1.29 * salmonella enterica subsp. enterica serovar typhimurium 25000.0 1 PMID:25005080 -3.1.1.29 * schizosaccharomyces pombe 20000.0 1 PMID:23892058 -3.1.1.29 * staphylococcus aureus 23000.0 2 PMID:11812233;PMID:26508479 -3.1.1.3 * acinetobacter baylyi 30000.0 1 PMID:20177822;PMID:7487042 -3.1.1.3 * acinetobacter calcoaceticus 32000.0 2 PMID:14550014;PMID:3453402 -3.1.1.3 * acinetobacter sp. 33000.0 2 PMID:12444965;PMID:18633735;PMID:18835775;PMID:21145735;PMID:7487042 -3.1.1.3 * aeromonas sp. 50000.0 1 PMID:18571355 -3.1.1.3 * amycolatopsis mediterranei 33000.0 1 PMID:12444965;PMID:21145735;PMID:7487042 -3.1.1.3 * aquipseudomonas alcaligenes 30000.0 1 PMID:20177822;PMID:7487042 -3.1.1.3 * aspergillus carneus 27000.0 1 * -3.1.1.3 * aspergillus fumigatus 38000.0 1 PMID:21744116 -3.1.1.3 * aspergillus nidulans 29000.0 1 PMID:10637060;PMID:10814595;PMID:1748875;PMID:9590625 -3.1.1.3 * aspergillus niger 40000.0 4 PMID:10907784;PMID:14766305;PMID:18633735;PMID:18835775;PMID:23202292 -3.1.1.3 * aspergillus oryzae 24000.0 1 PMID:14550014 -3.1.1.3 * aureobasidium pullulans 63500.0 3 PMID:18340544 -3.1.1.3 * bacillus cereus 42000.0 1 * -3.1.1.3 * bacillus licheniformis 81000.0 3 PMID:18237134;PMID:26049985;PMID:33548313 -3.1.1.3 * bacillus sp. (in: firmicutes) 46500.0 7 PMID:10839198;PMID:14550014;PMID:20127521;PMID:20574645 -3.1.1.3 * bacillus subtilis 62000.0 3 PMID:17385549;PMID:7487042 -3.1.1.3 * blastobotrys adeninivorans 100000.0 3 PMID:15942926 -3.1.1.3 * bos taurus 55000.0 3 PMID:17651673;PMID:3987686 -3.1.1.3 * brassica napus 300000.0 1 PMID:2268143 -3.1.1.3 * burkholderia cepacia 110000.0 6 PMID:12444965;PMID:15812860;PMID:18052929;PMID:1856176;PMID:18725331;PMID:21145735;PMID:23977086;PMID:7487042 -3.1.1.3 * burkholderia sp. 35000.0 1 * -3.1.1.3 * candida parapsilosis 48900.0 1 PMID:11895444 -3.1.1.3 * cephaloleia presignis 31000.0 2 PMID:10637060;PMID:10814595;PMID:14550014;PMID:1748875;PMID:9590625 -3.1.1.3 * chlamydomonas reinhardtii 65000.0 1 PMID:17395356;PMID:20574813;PMID:23042128 -3.1.1.3 * clostridium tetanomorphum 118000.0 2 * -3.1.1.3 * cordyceps militaris 69000.0 1 PMID:37201411 -3.1.1.3 * cupriavidus necator 38600.0 1 PMID:22588499 -3.1.1.3 * diutina rugosa 117000.0 5 PMID:11457462;PMID:16448188 -3.1.1.3 * ectopseudomonas mendocina 80000.0 1 PMID:12614891 -3.1.1.3 * equus caballus 48000.0 1 PMID:24368210 -3.1.1.3 * fagopyrum esculentum 171000.0 4 PMID:15563227 -3.1.1.3 * fusarium graminearum 61800.0 5 PMID:25919623 -3.1.1.3 * gallus gallus 53500.0 3 PMID:16154275;PMID:16780787;PMID:18679582 -3.1.1.3 * geobacillus sp. 44000.0 1 PMID:21531550 -3.1.1.3 * geobacillus stearothermophilus 62500.0 3 PMID:10737182;PMID:18997337;PMID:19130194 -3.1.1.3 * geobacillus thermocatenulatus 43000.0 3 PMID:12651113;PMID:14766305;PMID:18997337;PMID:19130194;PMID:23202292 -3.1.1.3 * geobacillus thermoleovorans 57000.0 6 PMID:19107605 -3.1.1.3 * geotrichum candidum 64000.0 1 * -3.1.1.3 * geotrichum marinum 62000.0 1 PMID:15233404 -3.1.1.3 * haloarcula sp. 45000.0 1 PMID:24789461 -3.1.1.3 * helianthus annuus 22000.0 1 PMID:15704496 -3.1.1.3 * heyndrickxia coagulans 103000.0 2 PMID:15802219;PMID:16290008 -3.1.1.3 * homarus americanus 65000.0 1 PMID:17395356;PMID:20574813;PMID:23042128 -3.1.1.3 * homo sapiens 67000.0 7 PMID:11040182;PMID:17401110;PMID:24368210;PMID:641046 -3.1.1.3 * hyphopichia burtonii 51000.0 1 PMID:14550014 -3.1.1.3 * jacaranda mimosifolia 43000.0 3 PMID:18553138 -3.1.1.3 * liza parsia 46500.0 2 * -3.1.1.3 * lysinibacillus sphaericus 40000.0 1 PMID:18571355 -3.1.1.3 * macruronus novaezelandiae 45000.0 1 PMID:20143156 -3.1.1.3 * meleagris gallopavo 50000.0 1 PMID:21272342 -3.1.1.3 * microbacterium phyllosphaerae 42000.0 1 PMID:18571355 -3.1.1.3 * micrococcus sp. 44600.0 1 * -3.1.1.3 * moesziomyces antarcticus 50000.0 3 PMID:18197630;PMID:18461981;PMID:20887757 -3.1.1.3 * mycobacterium tuberculosis 45000.0 1 PMID:16354661 -3.1.1.3 * neurospora crassa 54000.0 2 PMID:2958597 -3.1.1.3 * oncorhynchus tshawytscha 79600.0 2 PMID:20143156 -3.1.1.3 * oryctolagus cuniculus 49000.0 3 PMID:3382677;PMID:6520114 -3.1.1.3 * oryza sativa 40000.0 3 PMID:11743116;PMID:14766305;PMID:23202292 -3.1.1.3 * penaeus vannamei 196000.0 3 PMID:20965269 -3.1.1.3 * penicillium candidum 29000.0 1 PMID:11337984 -3.1.1.3 * penicillium cyclopium 110000.0 6 PMID:10637060;PMID:10814595;PMID:1748875;PMID:3651493;PMID:9590625 -3.1.1.3 * penicillium expansum 28000.0 1 PMID:18025580 -3.1.1.3 * penicillium roqueforti 25000.0 1 PMID:14550014 -3.1.1.3 * priestia megaterium 35000.0 1 PMID:15812860;PMID:1856176;PMID:23977086 -3.1.1.3 * proteus vulgaris 31000.0 1 PMID:10814595;PMID:14550014 -3.1.1.3 * pseudoalteromonas sp. 85000.0 1 PMID:18571355 -3.1.1.3 * pseudomonas aeruginosa 840000.0 16 PMID:10637060;PMID:10814595;PMID:14550014;PMID:1539972;PMID:16110344;PMID:16450840;PMID:17027868;PMID:1748875;PMID:1910141;PMID:21720839;PMID:2268143;PMID:25214220;PMID:3096967;PMID:7487042;PMID:8405431;PMID:9590625 -3.1.1.3 * pseudomonas fluorescens 64000.0 3 PMID:16233513;PMID:20147;PMID:7487042 -3.1.1.3 * pseudomonas fragi 33000.0 1 PMID:12444965;PMID:21145735;PMID:7487042 -3.1.1.3 * pseudomonas sp. 68000.0 7 PMID:10825531;PMID:14550014;PMID:18571355 -3.1.1.3 * psychrobacter sp. 90000.0 5 PMID:18051271;PMID:18571355 -3.1.1.3 * pyrococcus furiosus 82000.0 4 PMID:18400514 -3.1.1.3 * ralstonia sp. 32500.0 1 PMID:15596365 -3.1.1.3 * rattus norvegicus 180000.0 3 PMID:2051929;PMID:6269458 -3.1.1.3 * rhizopus arrhizus 32000.0 2 PMID:14550014;PMID:16842350 -3.1.1.3 * rhizopus homothallicus 29500.0 1 PMID:17652784 -3.1.1.3 * rhizopus japonicus 30000.0 2 PMID:3818576 -3.1.1.3 * rhizopus microsporus var. chinensis 63000.0 2 PMID:18809324 -3.1.1.3 * rhodotorula mucilaginosa 176000.0 2 * -3.1.1.3 * ricinus communis 60000.0 1 PMID:15322116 -3.1.1.3 * saccharolobus solfataricus 45000.0 1 PMID:10839198 -3.1.1.3 * saccharomyces cerevisiae 60000.0 1 PMID:24187129 -3.1.1.3 * sardinella aurita 43000.0 1 PMID:20383604;PMID:3651493 -3.1.1.3 * scorpio maurus 50000.0 2 PMID:16154275;PMID:16580184;PMID:16780787 -3.1.1.3 * serratia marcescens 140000.0 8 PMID:17395356;PMID:18051356;PMID:18571355;PMID:20574813;PMID:23042128 -3.1.1.3 * solanum lycopersicum 47500.0 1 PMID:15225633 -3.1.1.3 * staphylococcus aureus 110000.0 2 PMID:20383604;PMID:3651493 -3.1.1.3 * staphylococcus epidermidis 90000.0 3 PMID:14550014 -3.1.1.3 * staphylococcus simulans 158000.0 2 PMID:11698108 -3.1.1.3 * staphylococcus warneri 45500.0 1 PMID:11341932 -3.1.1.3 * staphylococcus xylosus 45000.0 2 PMID:16380267;PMID:17521919 -3.1.1.3 * streptomyces coelicolor 26970.0 2 * -3.1.1.3 * streptomyces sp. 17000.0 1 PMID:21909675 -3.1.1.3 * struthio camelus 45000.0 1 PMID:24789461 -3.1.1.3 * sus scrofa 240000.0 7 PMID:15812860;PMID:1856176;PMID:23977086;PMID:24368210;PMID:7278671;PMID:9799112 -3.1.1.3 * testudo graeca nabeulensis 45000.0 1 PMID:18362845 -3.1.1.3 * thermobifida fusca 29000.0 2 PMID:18658138 -3.1.1.3 * thermomyces lanuginosus 39000.0 1 * -3.1.1.3 * thermosyntropha lipolytica 57000.0 2 PMID:17933930 -3.1.1.3 * thermus thermophilus 34000.0 1 PMID:15862353 -3.1.1.3 * todarodes pacificus 27000.0 1 PMID:18377731 -3.1.1.3 * trichoderma reesei 23748.0 1 PMID:25219509 -3.1.1.3 * trichomonas vaginalis 33000.0 1 PMID:16236283 -3.1.1.3 * trichosporon asahii 54000.0 1 PMID:17027868;PMID:25214220 -3.1.1.3 * triticum aestivum 143000.0 2 PMID:34266327 -3.1.1.3 * tsukamurella paurometabola 52000.0 1 PMID:16604420 -3.1.1.3 * uncultured bacterium 43000.0 1 PMID:21678056 -3.1.1.3 * yarrowia lipolytica 41000.0 5 PMID:16624574;PMID:16931141 -3.1.1.31 * bos taurus 30000.0 2 PMID:3245836;PMID:3581437;PMID:6852020 -3.1.1.31 * dicentrarchus labrax 30000.0 2 PMID:3245836;PMID:6852020 -3.1.1.31 * giardia duodenalis 170000.0 1 PMID:30149622 -3.1.1.31 * homo sapiens 27529.0 1 PMID:10518023 -3.1.1.31 * mus musculus 178000.0 3 PMID:12831846 -3.1.1.31 * plasmodium berghei 110000.0 1 PMID:12615331 -3.1.1.31 * plasmodium falciparum 107000.0 1 PMID:16689939 -3.1.1.31 * pseudomonas aeruginosa 40000.0 1 PMID:18832304 -3.1.1.31 * trypanosoma brucei 30000.0 1 PMID:17196981 -3.1.1.31 * xanthomonas oryzae 25880.0 1 PMID:18997330 -3.1.1.31 * zymomonas mobilis 26000.0 2 * -3.1.1.32 * bos taurus 440000.0 4 PMID:8034719;PMID:8216258;PMID:8631903 -3.1.1.32 * capsicum annuum 45100.0 1 PMID:18036200 -3.1.1.32 * cavia porcellus 42000.0 2 PMID:7213780 -3.1.1.32 * corticium centrifugum 26800.0 1 * -3.1.1.32 * escherichia coli 60000.0 4 PMID:11997123;PMID:4946924 -3.1.1.32 * homo sapiens 90000.0 3 PMID:11788596;PMID:12963729 -3.1.1.32 * katsuwonus pelamis 71500.0 1 PMID:10666567 -3.1.1.32 * manduca sexta 155000.0 1 PMID:6833259 -3.1.1.32 * mesocricetus auratus 140000.0 2 PMID:3119595 -3.1.1.32 * polistes dominula 33502.0 1 PMID:16196201 -3.1.1.32 * polybia paulista 33961.0 1 PMID:17761205 -3.1.1.32 * rattus norvegicus 75000.0 6 PMID:19047760;PMID:2051928;PMID:3719001;PMID:3790533;PMID:7278676 -3.1.1.32 * serratia sp. xjf1 35000.0 2 PMID:22578870 -3.1.1.32 * streptomyces albidoflavus 28000.0 2 PMID:23772365 -3.1.1.32 * trypanosoma brucei 137000.0 2 PMID:17402937 -3.1.1.32 * trypanosoma cruzi 40000.0 3 PMID:11311140;PMID:23275096 -3.1.1.32 * vespa basalis 32000.0 1 PMID:19052363 -3.1.1.32 * vespula vulgaris 37000.0 2 PMID:20359368;PMID:21731687 -3.1.1.34 * bos taurus 96900.0 5 PMID:2015950;PMID:21698114;PMID:3523161;PMID:3782053;PMID:7106113;PMID:7165705;PMID:826537 -3.1.1.34 * cavia porcellus 110000.0 1 PMID:6802184 -3.1.1.34 * gallus gallus 121000.0 3 PMID:4041471;PMID:9406449 -3.1.1.34 * homo sapiens 67000.0 5 PMID:11483618;PMID:21698114;PMID:3782053;PMID:4030767;PMID:641046;PMID:7165705 -3.1.1.34 * mus musculus 50314.0 1 PMID:3597382 -3.1.1.34 * oncorhynchus mykiss 63000.0 1 PMID:7115310 -3.1.1.34 * rattus norvegicus 123000.0 7 PMID:21698114;PMID:3782053;PMID:510696;PMID:7165705;PMID:863923;PMID:9406449 -3.1.1.34 * sus scrofa 62000.0 2 PMID:4362067 -3.1.1.35 * acinetobacter calcoaceticus 75000.0 3 PMID:10601844 -3.1.1.35 * geobacillus sp. 70000.0 2 PMID:10601844 -3.1.1.36 * citrus nobilis x citrus deliciosa 250000.0 2 * -3.1.1.39 * actinoplanes missouriensis 59000.0 1 PMID:4191854 -3.1.1.4 * acanthophis rugosus 13810.0 1 PMID:12540524 -3.1.1.4 * aeropyrum pernix 18000.0 1 PMID:15135393 -3.1.1.4 * arabidopsis thaliana 17500.0 4 PMID:14550557;PMID:16140037 -3.1.1.4 * bos taurus 110000.0 7 PMID:11909855;PMID:6860643;PMID:8454568;PMID:8505299;PMID:9131165;PMID:9787801 -3.1.1.4 * bothrocophias hyoprora 14249.0 1 PMID:21496495 -3.1.1.4 * bothrops alternatus 17000.0 2 PMID:30289061 -3.1.1.4 * bothrops asper 16000.0 4 PMID:20026168 -3.1.1.4 * bothrops atrox 15000.0 1 PMID:11201998;PMID:11233174;PMID:11565904;PMID:12220717;PMID:12234622;PMID:7632717 -3.1.1.4 * bothrops insularis 14000.0 4 PMID:17140721;PMID:17953979 -3.1.1.4 * bothrops jararacussu 30000.0 2 PMID:11201998;PMID:11233174;PMID:11565904;PMID:12220717;PMID:12234622;PMID:7632717 -3.1.1.4 * bothrops leucurus 15000.0 1 PMID:16510123;PMID:20723574;PMID:21699995 -3.1.1.4 * bungarus caeruleus 29000.0 3 PMID:15659372;PMID:15721580 -3.1.1.4 * bungarus multicinctus 75000.0 3 PMID:12727275;PMID:1935962;PMID:26996495;PMID:422537;PMID:7217035;PMID:730754;PMID:7419504;PMID:7846689 -3.1.1.4 * caenorhabditis elegans 350000.0 5 PMID:23007400 -3.1.1.4 * calloselasma rhodostoma 14000.0 2 PMID:18249006 -3.1.1.4 * camelus dromedarius 13749.0 1 PMID:16733083 -3.1.1.4 * campylobacter concisus 34000.0 1 PMID:15150326;PMID:19463858 -3.1.1.4 * cavia porcellus 13900.0 1 PMID:8344288 -3.1.1.4 * clonorchis sinensis 34000.0 1 PMID:15150326;PMID:19463858 -3.1.1.4 * craspedocephalus borneensis 14034.0 3 PMID:15955061 -3.1.1.4 * craspedocephalus puniceus 14221.0 6 PMID:15955061 -3.1.1.4 * crotalus durissus terrificus 28900.0 6 PMID:11201998;PMID:11233174;PMID:11565904;PMID:12220717;PMID:12234622;PMID:17401196;PMID:21245808;PMID:24035779;PMID:7632717 -3.1.1.4 * crotalus lutosus 14145.0 2 PMID:12727275;PMID:1935962;PMID:26996495;PMID:422537;PMID:7217035;PMID:7419504;PMID:7846689 -3.1.1.4 * daboia russelii 28500.0 4 PMID:21356226;PMID:23898481;PMID:24333043;PMID:27089306 -3.1.1.4 * daboia russelii pulchella 28000.0 3 PMID:16122995 -3.1.1.4 * daboia russelii russelii 7224.0 2 PMID:16997639 -3.1.1.4 * dasyatis pastinaca 14000.0 2 PMID:21329523;PMID:23898481;PMID:24333043 -3.1.1.4 * diplodus annularis 15000.0 1 PMID:28287729 -3.1.1.4 * diplodus sargus 15000.0 1 PMID:31739040 -3.1.1.4 * echis carinatus 15000.0 4 PMID:12727275;PMID:16510123;PMID:1935962;PMID:20723574;PMID:21699995;PMID:26996495;PMID:422537;PMID:7217035;PMID:7419504;PMID:7846689 -3.1.1.4 * equus caballus 105000.0 2 PMID:10946009;PMID:6860643 -3.1.1.4 * eristicophis macmahoni 14000.0 1 PMID:12727275;PMID:1935962;PMID:26996495;PMID:422537;PMID:7217035;PMID:7419504;PMID:7846689 -3.1.1.4 * escherichia coli 29000.0 2 PMID:387750 -3.1.1.4 * exaiptasia diaphana 44000.0 2 PMID:11086212 -3.1.1.4 * gallus gallus 14170.0 2 PMID:19645724 -3.1.1.4 * gloydius halys 14000.0 1 PMID:23143242 -3.1.1.4 * gloydius shedaoensis 19000.0 2 PMID:14732871 -3.1.1.4 * gloydius ussuriensis 17000.0 2 PMID:15618013 -3.1.1.4 * hexaplex trunculus 30000.0 1 PMID:19932080 -3.1.1.4 * homo sapiens 135000.0 20 PMID:10336645;PMID:11080674;PMID:11909855;PMID:12039969;PMID:1599975;PMID:1730245;PMID:18632668;PMID:18931897;PMID:1903717;PMID:20053941;PMID:20138108;PMID:6860643;PMID:8328965;PMID:8399335;PMID:9214693;PMID:9219901;PMID:922032;PMID:9767110;PMID:9787801 -3.1.1.4 * hydrophis hardwickii 14000.0 1 PMID:12727275;PMID:1935962;PMID:26996495;PMID:422537;PMID:7217035;PMID:7419504;PMID:7846689 -3.1.1.4 * lachesis muta 18000.0 1 PMID:12007562 -3.1.1.4 * laticauda semifasciata 14000.0 1 PMID:12727275;PMID:1935962;PMID:26996495;PMID:422537;PMID:7217035;PMID:7419504;PMID:7846689 -3.1.1.4 * lonomia obliqua 15000.0 1 PMID:16510123;PMID:20723574;PMID:21699995 -3.1.1.4 * macrovipera lebetina transmediterranea 13638.0 2 PMID:19351557 -3.1.1.4 * mammalia 114000.0 8 PMID:11080674 -3.1.1.4 * meleagris gallopavo 14000.0 1 PMID:14586101 -3.1.1.4 * mesocricetus auratus 140000.0 3 PMID:3119595;PMID:8940072 -3.1.1.4 * micropechis ikaheca 14020.0 3 PMID:11342029 -3.1.1.4 * micrurus dumerilii carinicauda 15552.0 2 PMID:16198388 -3.1.1.4 * micrurus spixii 12809.0 1 PMID:26095535 -3.1.1.4 * millepora platyphylla 32500.0 1 PMID:15683837 -3.1.1.4 * mus musculus 88000.0 2 PMID:11080674;PMID:20332422 -3.1.1.4 * naja atra 13260.0 2 PMID:9735349 -3.1.1.4 * naja haje 15840.0 2 PMID:19622365 -3.1.1.4 * naja kaouthia 13346.0 2 PMID:15081888 -3.1.1.4 * naja naja 13262.0 3 PMID:15134835;PMID:16574178;PMID:7278679 -3.1.1.4 * naja sumatrana 15000.0 1 PMID:34941697 -3.1.1.4 * ophiophagus hannah 14000.0 1 PMID:8593185 -3.1.1.4 * oryctolagus cuniculus 15700.0 3 PMID:10833266;PMID:2223865 -3.1.1.4 * ovis aries 18500.0 2 PMID:7278677 -3.1.1.4 * pagrus major 15000.0 1 PMID:11201998;PMID:11233174;PMID:11565904;PMID:12220717;PMID:12234622;PMID:7632717 -3.1.1.4 * photobacterium damselae 43000.0 1 PMID:24601085 -3.1.1.4 * priestia megaterium 66000.0 1 PMID:18689470 -3.1.1.4 * protobothrops flavoviridis 28000.0 2 PMID:12727275;PMID:1935962;PMID:26996495;PMID:422537;PMID:7217035;PMID:7419504;PMID:7846689 -3.1.1.4 * protobothrops jerdonii 15000.0 1 PMID:11201998;PMID:11233174;PMID:11565904;PMID:12220717;PMID:12234622;PMID:7632717 -3.1.1.4 * protobothrops mangshanensis 13972.0 2 PMID:17620723;PMID:18295812 -3.1.1.4 * pseudechis papuanus 15000.0 1 PMID:11201998;PMID:11233174;PMID:11565904;PMID:12220717;PMID:12234622;PMID:7632717 -3.1.1.4 * pseudomonas aeruginosa 75000.0 1 PMID:28993456 -3.1.1.4 * rattus norvegicus 500000.0 10 PMID:10461922;PMID:14744027;PMID:4202714;PMID:7998924;PMID:8148815;PMID:8925928 -3.1.1.4 * scolopendra viridis 13750.0 1 PMID:19285520 -3.1.1.4 * solanum tuberosum 56000.0 1 PMID:11589694 -3.1.1.4 * sparus aurata 15000.0 1 PMID:31739040 -3.1.1.4 * streptomyces coelicolor 13530.0 3 PMID:16809051 -3.1.1.4 * struthio camelus 14000.0 1 PMID:17656163 -3.1.1.4 * sus scrofa 15000.0 5 PMID:1091;PMID:3295782;PMID:4772678;PMID:6860643 -3.1.1.4 * trimorphodon lambda 14000.0 2 PMID:15225559 -3.1.1.4 * trypanosoma congolense 34500.0 3 PMID:8324881 -3.1.1.4 * vibrio mimicus 53000.0 1 PMID:12387827 -3.1.1.4 * vicia faba 48000.0 1 PMID:10889255 -3.1.1.40 * lasallia pustulata 42000.0 1 PMID:5116606 -3.1.1.41 * amycolatopsis lactamdurans 72100.0 1 PMID:11030579 -3.1.1.41 * bacillus subtilis 280000.0 6 PMID:16232499;PMID:23828600;PMID:241292 -3.1.1.41 * halalkalibacterium halodurans 105000.0 1 PMID:31986559 -3.1.1.41 * hapsidospora chrysogena 38230.0 3 PMID:11759684;PMID:7998 -3.1.1.41 * limosilactobacillus antri 127000.0 1 PMID:31986559 -3.1.1.41 * paenibacillus sp. r4 234000.0 1 * -3.1.1.41 * rhodotorula glutinis 141000.0 2 * -3.1.1.41 * rhodotorula toruloides 80000.0 2 PMID:9406399 -3.1.1.41 * staphylococcus sp. 44000.0 1 * -3.1.1.41 * thermotoga maritima 220000.0 2 PMID:28097692 -3.1.1.42 * aspergillus niger 240000.0 5 PMID:15607224;PMID:17630312;PMID:7385941;PMID:7445677 -3.1.1.42 * aspergillus sojae 180000.0 2 PMID:18773200 -3.1.1.43 * acetobacter pasteurianus 300000.0 9 PMID:11772629;PMID:29556427 -3.1.1.43 * bacillus mycoides 160000.0 2 PMID:11432787 -3.1.1.43 * homo sapiens 27000.0 2 * -3.1.1.43 * pseudomonas melanogenum 146000.0 2 * -3.1.1.43 * rattus norvegicus 29000.0 1 * -3.1.1.43 * stenotrophomonas maltophilia 300000.0 1 PMID:29556427 -3.1.1.43 * xanthomonas campestris 68000.0 1 * -3.1.1.43 * xanthomonas citri 280000.0 4 PMID:12684501 -3.1.1.43 * xanthomonas sp. 70000.0 1 * -3.1.1.45 * burkholderia cepacia 39000.0 1 PMID:7684040;PMID:7765840 -3.1.1.45 * cupriavidus necator 58000.0 3 PMID:7765840 -3.1.1.45 * pseudomonas knackmussii 28500.0 3 PMID:3804973;PMID:3804974;PMID:7765840 -3.1.1.45 * pseudomonas putida 28000.0 4 PMID:3804974;PMID:7765840 -3.1.1.45 * pseudomonas reinekei 37000.0 2 PMID:18789896 -3.1.1.45 * pseudomonas sp. 85000.0 2 PMID:14617643 -3.1.1.45 * rhodococcus opacus 30000.0 3 PMID:7765840;PMID:9495745 -3.1.1.45 * saccharolobus solfataricus 29000.0 1 PMID:20655986 -3.1.1.47 * bos taurus 100000.0 12 PMID:11239086;PMID:11377588;PMID:11983068;PMID:15802790;PMID:17827718;PMID:7673213;PMID:8360169;PMID:9349753 -3.1.1.47 * cavia porcellus 63000.0 3 PMID:12547653;PMID:7822257;PMID:8947850 -3.1.1.47 * homo sapiens 70000.0 23 PMID:11080681;PMID:11133692;PMID:12547653;PMID:12865731;PMID:12934648;PMID:18155631;PMID:18489851;PMID:18784071;PMID:21844189;PMID:3558407;PMID:7700381;PMID:8440681 -3.1.1.47 * mus musculus 63000.0 2 PMID:7921789 -3.1.1.47 * nippostrongylus brasiliensis 64000.0 3 PMID:8713083 -3.1.1.47 * rattus norvegicus 66000.0 4 PMID:10867005;PMID:11105997 -3.1.1.47 * rhodnius prolixus 28000.0 1 PMID:21439293 -3.1.1.47 * schizosaccharomyces pombe 55000.0 2 PMID:18489912 -3.1.1.47 * sus scrofa 60000.0 4 PMID:16272147 -3.1.1.48 * aspergillus fumigatus 32700.0 1 PMID:17586718 -3.1.1.49 * brassica napus 47000.0 2 PMID:18036206 -3.1.1.49 * sinapis alba 40000.0 1 * -3.1.1.5 * arabidopsis thaliana 40900.0 2 PMID:20345607;PMID:8816850 -3.1.1.5 * bacillus subtilis 24669.0 1 PMID:20057119 -3.1.1.5 * bos taurus 67000.0 6 PMID:4421163;PMID:4693514 -3.1.1.5 * caldibacillus thermoamylovorans 150000.0 1 PMID:29051101 -3.1.1.5 * candida albicans 84000.0 3 PMID:2007179;PMID:7619859 -3.1.1.5 * cryptococcus bacillisporus 670000.0 3 PMID:15320865 -3.1.1.5 * cryptococcus neoformans 232000.0 4 PMID:10749672;PMID:14563553;PMID:15320865 -3.1.1.5 * escherichia coli 39500.0 2 PMID:238979;PMID:3908447 -3.1.1.5 * homo sapiens 130000.0 5 PMID:19019078;PMID:19439193;PMID:19501189;PMID:24657844 -3.1.1.5 * hordeum vulgare 40000.0 1 PMID:4083901 -3.1.1.5 * legionella pneumophila 90000.0 2 PMID:11222614 -3.1.1.5 * moraxella bovis 66000.0 4 PMID:11673447;PMID:17709258 -3.1.1.5 * mus musculus 30000.0 3 PMID:3384824 -3.1.1.5 * mycobacterium lepraemurium 37000.0 1 PMID:20345607;PMID:8816850 -3.1.1.5 * oryctolagus cuniculus 23000.0 1 PMID:6833297 -3.1.1.5 * penicillium chrysogenum 116000.0 3 PMID:3545077;PMID:4631772 -3.1.1.5 * pseudomonas aeruginosa 20000.0 1 PMID:23874889 -3.1.1.5 * pyrococcus furiosus 32040.0 2 PMID:18400514 -3.1.1.5 * rattus norvegicus 78000.0 5 PMID:7278668;PMID:8631810;PMID:9442064 -3.1.1.5 * saccharomyces cerevisiae 420000.0 4 PMID:6368532;PMID:6380591 -3.1.1.5 * schistosoma japonicum 26000.0 6 PMID:17709268 -3.1.1.5 * schizosaccharomyces pombe 300000.0 1 PMID:8782402 -3.1.1.5 * sus scrofa 65000.0 4 PMID:19588246;PMID:7772041 -3.1.1.5 * taiwanofungus camphoratus 35500.0 1 PMID:19849771 -3.1.1.5 * thermococcus kodakarensis 32000.0 2 PMID:22622648 -3.1.1.5 * vibrio cholerae serotype o1 81600.0 1 PMID:24532770 -3.1.1.51 * mus musculus 60000.0 2 PMID:3864781;PMID:6946062 -3.1.1.52 * bos taurus 18521.0 3 PMID:7083039 -3.1.1.53 * bos taurus 56500.0 1 PMID:3149520 -3.1.1.53 * equus caballus 56500.0 1 PMID:3149520 -3.1.1.53 * equus sp. 54000.0 1 PMID:18246423 -3.1.1.53 * influenza c virus 88000.0 5 PMID:3149520;PMID:3242542 -3.1.1.53 * isavirus salaris 40000.0 3 PMID:18799134 -3.1.1.53 * mus musculus 250000.0 2 PMID:8662838 -3.1.1.53 * phocaeicola vulgatus 51600.0 2 PMID:35503212 -3.1.1.53 * rattus norvegicus 65000.0 12 PMID:12948030;PMID:2695768;PMID:2808434;PMID:8486688 -3.1.1.54 * tagetes patula 67000.0 1 * -3.1.1.55 * cavia porcellus 57100.0 2 PMID:6704404 -3.1.1.55 * homo sapiens 70000.0 4 PMID:21844189 -3.1.1.55 * rattus norvegicus 35000.0 1 PMID:2383281 -3.1.1.56 * homo sapiens 76000.0 5 PMID:18552983;PMID:3369858;PMID:4076172 -3.1.1.56 * mus musculus 31800.0 1 PMID:18552983 -3.1.1.56 * saccharomyces cerevisiae 56900.0 3 PMID:10427036;PMID:18707125 -3.1.1.57 * phytopseudomonas straminea 34345.0 4 PMID:15277747;PMID:6841353 -3.1.1.58 * bacillus subtilis 28174.0 1 PMID:15598884 -3.1.1.58 * cryptococcus neoformans 25000.0 2 PMID:11953374;PMID:12933895 -3.1.1.58 * neurospora crassa 76000.0 1 PMID:6217857 -3.1.1.58 * staphylococcus epidermidis 33113.0 2 PMID:23866051 -3.1.1.59 * apis mellifera 64000.0 1 PMID:18308604 -3.1.1.59 * dysdercus cingulatus 66000.0 2 PMID:21086726 -3.1.1.59 * galleria mellonella 60000.0 1 * -3.1.1.59 * heliothis virescens 61012.0 1 PMID:2745451 -3.1.1.59 * leptinotarsa decemlineata 120000.0 2 PMID:9177132 -3.1.1.59 * lymantria dispar 62000.0 2 PMID:10727897 -3.1.1.59 * manduca sexta 66000.0 2 PMID:2254326;PMID:4062303 -3.1.1.59 * tenebrio molitor 66000.0 2 PMID:12706627 -3.1.1.59 * trichoplusia ni 66000.0 4 PMID:3654630 -3.1.1.6 * acinetobacter sp. 20000.0 1 * -3.1.1.6 * aspergillus niger 160000.0 4 PMID:1245482;PMID:4197268;PMID:6870256;PMID:7445676;PMID:8010767 -3.1.1.6 * aspergillus oryzae 40000.0 3 PMID:16901567;PMID:6870256;PMID:7576539 -3.1.1.6 * bacillus pumilus 190000.0 2 PMID:10215579;PMID:23132590 -3.1.1.6 * bacillus subtilis 160000.0 2 PMID:4197268;PMID:7445676 -3.1.1.6 * bos taurus 70000.0 2 PMID:3689793 -3.1.1.6 * candida bororiensis 35000.0 1 PMID:1245482;PMID:6870256;PMID:8010767 -3.1.1.6 * cichorium intybus 65000.0 3 PMID:16339785 -3.1.1.6 * citrus sinensis 45000.0 1 * -3.1.1.6 * drosophila mojavensis 95000.0 1 * -3.1.1.6 * eleusine coracana 79400.0 2 PMID:17263491 -3.1.1.6 * escherichia coli 40000.0 1 PMID:10215579;PMID:23132590 -3.1.1.6 * exiguobacterium antarcticum 66000.0 1 PMID:31229546 -3.1.1.6 * fibrobacter succinogenes 55000.0 1 PMID:2082827 -3.1.1.6 * homo sapiens 52000.0 4 PMID:18513186 -3.1.1.6 * kluyveromyces marxianus 29000.0 1 PMID:18029043 -3.1.1.6 * lichtheimia corymbifera 36000.0 1 * -3.1.1.6 * marchantia polymorpha 54000.0 4 * -3.1.1.6 * meyerozyma guilliermondii 67000.0 2 PMID:10736022 -3.1.1.6 * nocardia sp. 84000.0 2 PMID:4436255 -3.1.1.6 * petroselinum crispum 36000.0 2 PMID:1245482;PMID:6870256;PMID:7576539;PMID:8010767 -3.1.1.6 * phocaeicola vulgatus 51600.0 1 PMID:35503212 -3.1.1.6 * populus trichocarpa 42800.0 1 PMID:22247250 -3.1.1.6 * sclerotinia sp. 78500.0 1 * -3.1.1.6 * streptomyces lividans 34000.0 1 PMID:8920994 -3.1.1.6 * streptomyces sp. 155000.0 2 * -3.1.1.6 * sus scrofa 30000.0 1 PMID:3921058 -3.1.1.6 * talaromyces purpureogenus 48000.0 2 PMID:8756392 -3.1.1.6 * trichoderma reesei 68000.0 5 PMID:18978092;PMID:3689793 -3.1.1.60 * gordonia sp. 5f 370000.0 1 PMID:31266305 -3.1.1.60 * triticum aestivum 38000.0 2 PMID:6468391 -3.1.1.61 * bacillus subtilis 41000.0 1 PMID:6424705 -3.1.1.61 * rattus norvegicus 31000.0 1 PMID:6469959 -3.1.1.61 * salmonella enterica subsp. enterica serovar typhimurium 37000.0 1 PMID:2991277;PMID:6387376 -3.1.1.64 * bos taurus 65000.0 2 PMID:19049981;PMID:20304090 -3.1.1.64 * danio rerio 61000.0 1 PMID:21235714 -3.1.1.64 * gallus gallus 60927.0 1 PMID:18216020 -3.1.1.64 * homo sapiens 61000.0 2 PMID:16150724;PMID:19049981 -3.1.1.67 * homo sapiens 62000.0 9 PMID:1885604;PMID:2025229;PMID:2354155;PMID:2599089;PMID:6487591;PMID:8899561;PMID:9546637 -3.1.1.67 * oryctolagus cuniculus 50000.0 2 PMID:2599089;PMID:6487591 -3.1.1.67 * rattus norvegicus 180000.0 6 PMID:11424227;PMID:11884245;PMID:1429692;PMID:16689928;PMID:9049433 -3.1.1.68 * haloferax volcanii 28000.0 2 PMID:28108583;PMID:28854683 -3.1.1.7 * anopheles gambiae 130000.0 3 PMID:19607916 -3.1.1.7 * aphis gossypii 63500.0 1 PMID:12210959 -3.1.1.7 * apis mellifera 185000.0 4 PMID:23144990 -3.1.1.7 * arapaima gigas 299000.0 1 PMID:24980148 -3.1.1.7 * bactrocera dorsalis 116000.0 3 PMID:15315367;PMID:23007913 -3.1.1.7 * blattella germanica 160000.0 4 PMID:20738424 -3.1.1.7 * bos taurus 250000.0 3 PMID:2031716;PMID:6501251 -3.1.1.7 * bungarus multicinctus 140000.0 2 PMID:155947 -3.1.1.7 * cimex lectularius 130000.0 1 PMID:30266661 -3.1.1.7 * ciona intestinalis 70000.0 2 PMID:7417454 -3.1.1.7 * colossoma macropomum 299000.0 4 PMID:24980148 -3.1.1.7 * cyprinus carpio 73000.0 3 PMID:19121395 -3.1.1.7 * dendrobaena veneta 133000.0 5 PMID:8681969 -3.1.1.7 * diopatra neapolitana 173000.0 1 PMID:27777085 -3.1.1.7 * electrophorus electricus 67000.0 1 PMID:15980188;PMID:16366609;PMID:8725010 -3.1.1.7 * eledone moschata 136000.0 2 PMID:9761457 -3.1.1.7 * gallus gallus 420000.0 2 PMID:6208193 -3.1.1.7 * haemonchus contortus 144000.0 1 * -3.1.1.7 * heterorhabditis bacteriophora 180000.0 2 PMID:26545490 -3.1.1.7 * homo sapiens 260000.0 4 PMID:21682268;PMID:23494216;PMID:4847222 -3.1.1.7 * macroptilium atropurpureum 121000.0 1 PMID:18046576 -3.1.1.7 * mus musculus 66000.0 1 PMID:12672481 -3.1.1.7 * musca domestica 501000.0 7 PMID:687628;PMID:836849;PMID:953030;PMID:953031 -3.1.1.7 * mytilus galloprovincialis 68000.0 1 PMID:11311211 -3.1.1.7 * nippostrongylus brasiliensis 72000.0 3 PMID:10092608;PMID:16302258 -3.1.1.7 * oreochromis mossambicus 244000.0 2 PMID:31874993 -3.1.1.7 * oreochromis niloticus 252000.0 1 PMID:24980148 -3.1.1.7 * ovis aries 201500.0 2 PMID:21499785 -3.1.1.7 * rachycentron canadum 244000.0 1 PMID:24980148 -3.1.1.7 * rattus norvegicus 328000.0 2 PMID:7213745 -3.1.1.7 * rhynchophorus ferrugineus 57000.0 2 PMID:31751747 -3.1.1.7 * rhyzopertha dominica 107000.0 2 PMID:9669090 -3.1.1.7 * schistosoma mansoni 450000.0 1 PMID:6541056 -3.1.1.7 * schizaphis graminum 130000.0 5 PMID:11520688;PMID:20146377 -3.1.1.7 * stomoxys calcitrans 77573.0 1 PMID:21872994 -3.1.1.7 * torpedo sp. 100000.0 2 PMID:6288713 -3.1.1.7 * trichostrongylus colubriformis 189000.0 2 PMID:8052513 -3.1.1.7 * walterinnesia aegyptia 67000.0 1 PMID:15980188;PMID:16366609;PMID:8725010 -3.1.1.7 * zea mays 67000.0 1 PMID:15980188;PMID:16366609;PMID:8725010 -3.1.1.70 * aspergillus niger 35000.0 1 PMID:2632040 -3.1.1.72 * aspergillus niger 30480.0 1 * -3.1.1.72 * aspergillus oryzae 31000.0 1 PMID:16129506 -3.1.1.72 * bacillus pumilus 260000.0 7 PMID:10215579;PMID:11717513;PMID:15769599 -3.1.1.72 * bacillus subtilis 223000.0 2 PMID:23828600 -3.1.1.72 * caldanaerobacter subterraneus 34000.0 1 PMID:24317066 -3.1.1.72 * clostridium cellulovorans 57038.0 1 PMID:12450866 -3.1.1.72 * coprinopsis cinerea 65500.0 4 PMID:23180549 -3.1.1.72 * fibrobacter succinogenes 60500.0 3 PMID:16333341;PMID:2082827 -3.1.1.72 * halalkalibacterium halodurans 105000.0 1 PMID:31986559 -3.1.1.72 * limosilactobacillus antri 127000.0 1 PMID:31986559 -3.1.1.72 * paenibacillus sp. r4 234000.0 2 PMID:30379876 -3.1.1.72 * phanerodontia chrysosporium 63000.0 3 PMID:23287498 -3.1.1.72 * rasamsonia emersonii 32000.0 1 PMID:22407679 -3.1.1.72 * schizophyllum commune 31000.0 3 PMID:14511913;PMID:21029756;PMID:8141793 -3.1.1.72 * streptomyces lividans 34000.0 1 PMID:14511913 -3.1.1.72 * talaromyces purpureogenus 48000.0 4 PMID:14511913;PMID:17008082;PMID:8756392 -3.1.1.72 * termitomyces clypeatus 30000.0 1 PMID:12790630 -3.1.1.72 * thermoanaerobacterium saccharolyticum 195000.0 6 PMID:7574610 -3.1.1.72 * thermobifida fusca 80000.0 4 PMID:16348531;PMID:22578869 -3.1.1.72 * trichoderma reesei 34000.0 3 PMID:14511913;PMID:8647098 -3.1.1.72 * volvariella volvacea 39900.0 3 PMID:17623028;PMID:19473250 -3.1.1.73 * acetivibrio thermocellus 2000000.0 4 PMID:10671457;PMID:16702605;PMID:17989872 -3.1.1.73 * aspergillus awamori 112000.0 11 PMID:17031032;PMID:17989872;PMID:18830967;PMID:19241534;PMID:19644688;PMID:19756576;PMID:20138908;PMID:26282562;PMID:9836439 -3.1.1.73 * aspergillus flavus 40000.0 2 PMID:23981381 -3.1.1.73 * aspergillus nidulans 130000.0 4 PMID:17043824;PMID:17989872;PMID:19644688 -3.1.1.73 * aspergillus niger 150000.0 21 PMID:11931668;PMID:12743752;PMID:1482195;PMID:15294290;PMID:16702605;PMID:16714088;PMID:17027758;PMID:17973091;PMID:17989872;PMID:19644688;PMID:23606660;PMID:25969986;PMID:8679110;PMID:9406381 -3.1.1.73 * aspergillus ochraceus 26500.0 1 * -3.1.1.73 * aspergillus oryzae 101000.0 9 PMID:19242690;PMID:19644688;PMID:25066066 -3.1.1.73 * aspergillus sp. 42000.0 1 PMID:10231593;PMID:17989872 -3.1.1.73 * aspergillus terreus 76000.0 6 PMID:12743752;PMID:16714088;PMID:17989872;PMID:23606660;PMID:25969986;PMID:26282562 -3.1.1.73 * aspergillus tubingensis 36000.0 3 PMID:17989872;PMID:19644688;PMID:9406381 -3.1.1.73 * aspergillus usamii 36000.0 3 PMID:12743752;PMID:16714088;PMID:23606660;PMID:24052228;PMID:25969986 -3.1.1.73 * aureobasidium pullulans 210000.0 1 PMID:12957952 -3.1.1.73 * burkholderia pyrrocinia 480000.0 2 PMID:35036272 -3.1.1.73 * butyrivibrio proteoclasticus 75000.0 1 PMID:20058325 -3.1.1.73 * caldanaerobacter subterraneus subsp. tengcongensis 36000.0 3 PMID:20127235 -3.1.1.73 * cellvibrio japonicus 59000.0 1 * -3.1.1.73 * eleusine coracana 16500.0 1 PMID:17944530 -3.1.1.73 * equus quagga 31200.0 1 PMID:22441123 -3.1.1.73 * fusarium oxysporum 62000.0 10 PMID:16702605;PMID:18414848;PMID:19644688 -3.1.1.73 * fusarium proliferatum 31000.0 1 * -3.1.1.73 * lactarius hatsudake 55000.0 1 PMID:27519296 -3.1.1.73 * lactobacillus acidophilus 59200.0 2 PMID:15066833;PMID:37446348 -3.1.1.73 * lentilactobacillus buchneri 60000.0 1 PMID:36569051 -3.1.1.73 * limosilactobacillus fermentum 29600.0 2 * -3.1.1.73 * neocallimastix sp. 69000.0 8 PMID:1482195;PMID:16702605;PMID:19644688 -3.1.1.73 * neurospora crassa 35040.0 8 PMID:14595525;PMID:14661116;PMID:19644688 -3.1.1.73 * penicillium chrysogenum 62000.0 1 * -3.1.1.73 * penicillium expansum 65000.0 2 PMID:9449810 -3.1.1.73 * penicillium sumatraense 36000.0 1 * -3.1.1.73 * piromyces sp. 'equi' 55500.0 2 PMID:16702605;PMID:17973091;PMID:19644688 -3.1.1.73 * pleurotus eryngii 67000.0 2 PMID:24607359 -3.1.1.73 * pleurotus giganteus 61000.0 1 PMID:25065258 -3.1.1.73 * pseudomonas fluorescens 58500.0 1 PMID:16702605 -3.1.1.73 * rusa unicolor 18600.0 1 PMID:22441123 -3.1.1.73 * russula virescens 62000.0 1 PMID:24142352 -3.1.1.73 * streptococcus thermophilus 33000.0 2 * -3.1.1.73 * streptomyces ambofaciens 43000.0 1 PMID:19767844 -3.1.1.73 * streptomyces cinnamoneus 52000.0 2 PMID:25093500 -3.1.1.73 * streptomyces olivochromogenes 29000.0 1 PMID:1663152 -3.1.1.73 * talaromyces funiculosus 53000.0 5 PMID:11082184;PMID:16702605;PMID:19644688 -3.1.1.73 * talaromyces pinophilus 57000.0 1 PMID:1426561 -3.1.1.73 * talaromyces stipitatus 72000.0 11 PMID:12767807;PMID:15006424;PMID:17989872;PMID:19644688 -3.1.1.73 * thermoclostridium stercorarium 33000.0 2 PMID:10747226 -3.1.1.73 * thermothelomyces heterothallicus 43000.0 3 PMID:19644688 -3.1.1.73 * xylanibacter ruminicola 124000.0 4 PMID:19304844;PMID:31812598 -3.1.1.74 * alternaria brassicicola 24000.0 2 PMID:20306187 -3.1.1.74 * arabidopsis 39200.0 1 PMID:18713314;PMID:19996150 -3.1.1.74 * ascochyta rabiei 22000.0 1 PMID:9167273 -3.1.1.74 * aspergillus nidulans 30100.0 1 PMID:18713314 -3.1.1.74 * aspergillus niger 22800.0 1 PMID:23540930 -3.1.1.74 * botrytis cinerea 110000.0 3 PMID:10077849;PMID:18713314 -3.1.1.74 * burkholderia cepacia 26500.0 2 PMID:23863287 -3.1.1.74 * colletotrichum gloeosporioides 39000.0 5 PMID:18983850;PMID:23468570;PMID:24910973 -3.1.1.74 * coprinopsis cinerea 20000.0 5 PMID:19201950 -3.1.1.74 * fusarium graminearum 36400.0 1 PMID:18713314 -3.1.1.74 * fusarium oxysporum f. sp. lycopersici 21700.0 1 PMID:18705871 -3.1.1.74 * fusarium sambucinum 24300.0 1 PMID:9910 -3.1.1.74 * fusarium solani 23400.0 4 PMID:239740 -3.1.1.74 * fusarium vanettenii 24900.0 2 * -3.1.1.74 * monilinia fructicola 20800.0 4 PMID:11051094;PMID:11929215 -3.1.1.74 * neurospora crassa 39200.0 1 PMID:18713314;PMID:19996150 -3.1.1.74 * pseudomonas putida 30000.0 1 PMID:3130804 -3.1.1.74 * pyricularia grisea 41200.0 1 PMID:18713314 -3.1.1.74 * sclerotinia sclerotiorum 45000.0 2 PMID:25149470 -3.1.1.74 * thermobifida fusca 32000.0 4 * -3.1.1.74 * thermothielavioides terrestris 27900.0 1 PMID:26041215 -3.1.1.74 * trichoderma harzianum 29000.0 1 PMID:18987860 -3.1.1.74 * trichoderma reesei 23748.0 1 PMID:25219509 -3.1.1.74 * venturia inaequalis 23000.0 2 * -3.1.1.75 * agrobacterium sp. 46000.0 2 * -3.1.1.75 * alcaligenes faecalis 95500.0 1 PMID:7646009 -3.1.1.75 * arthrobacter sp. 47000.0 1 PMID:11440137 -3.1.1.75 * aspergillus fumigatus 63744.0 1 * -3.1.1.75 * caldimonas sp. 49360.0 2 PMID:15340791 -3.1.1.75 * cereibacter sphaeroides 46500.0 1 PMID:15386104 -3.1.1.75 * cupriavidus necator 39200.0 4 PMID:16199568;PMID:24907326 -3.1.1.75 * ectopseudomonas mendocina 59400.0 2 * -3.1.1.75 * leptothrix sp. (in: b-proteobacteria) 104000.0 1 * -3.1.1.75 * microbacterium saperdae 42700.0 1 * -3.1.1.75 * paucimonas lemoignei 53000.0 2 PMID:12007811 -3.1.1.75 * penicillium simplicissimum 36000.0 1 * -3.1.1.75 * penicillium sp. 46800.0 3 * -3.1.1.75 * priestia megaterium 38000.0 2 PMID:19561190 -3.1.1.75 * pseudomonas putida 68910.0 2 PMID:19103481 -3.1.1.75 * purpureocillium lilacinum 45000.0 1 * -3.1.1.75 * rhodospirillum rubrum 35250.0 2 PMID:15489436 -3.1.1.75 * streptomyces ascomycinicus 48400.0 2 PMID:23951224 -3.1.1.75 * streptomyces kashimirensis 45000.0 2 PMID:19133504 -3.1.1.75 * streptomyces roseolus 28000.0 1 PMID:22865072 -3.1.1.75 * streptomyces sp. 62000.0 3 PMID:16614903 -3.1.1.75 * talaromyces funiculosus 37000.0 1 PMID:1929416 -3.1.1.75 * thermobifida sp. bcc23166 70000.0 3 PMID:19002683 -3.1.1.75 * thermus thermophilus hb8 42000.0 1 PMID:19214501 -3.1.1.76 * aquipseudomonas alcaligenes 30323.0 4 PMID:11888314;PMID:15340783;PMID:15995648;PMID:20937103;PMID:22858467 -3.1.1.76 * caldimonas thermodepolymerans 28000.0 1 PMID:15340783;PMID:15995648;PMID:20937103 -3.1.1.76 * paracoccus denitrificans 49300.0 1 PMID:11267773 -3.1.1.76 * pseudomonas fluorescens 48000.0 5 PMID:11217416;PMID:20400568;PMID:7961472;PMID:8476295 -3.1.1.76 * pseudomonas luteola 28000.0 1 * -3.1.1.76 * pseudomonas putida 31283.0 2 PMID:15340783;PMID:15604801;PMID:15995648;PMID:20937103 -3.1.1.76 * pseudomonas sp. 115000.0 1 PMID:16232726 -3.1.1.76 * streptomyces roseolus 28000.0 1 PMID:22865072 -3.1.1.76 * streptomyces sp. 28000.0 3 PMID:12785312 -3.1.1.76 * streptomyces venezuelae 27000.0 1 PMID:22695803 -3.1.1.76 * thermus thermophilus 28000.0 1 PMID:15340783;PMID:15995648;PMID:20937103 -3.1.1.77 * homo sapiens 60000.0 9 PMID:1883828;PMID:2549069;PMID:8089145 -3.1.1.78 * rauvolfia serpentina benth. ex kurz 60000.0 2 PMID:10691977;PMID:12071952 -3.1.1.79 * bos taurus 84000.0 2 PMID:14725507;PMID:2029545;PMID:2930517;PMID:2988858;PMID:3196730;PMID:3708011 -3.1.1.79 * falsihalocynthiibacter arcticus 30000.0 2 PMID:31694309 -3.1.1.79 * halalkalibacterium halodurans 42000.0 1 PMID:28710671 -3.1.1.79 * homo sapiens 116000.0 6 PMID:11277912;PMID:14725507;PMID:15260473;PMID:18492774;PMID:2557074 -3.1.1.79 * mus musculus 84000.0 1 PMID:18762171 -3.1.1.79 * ovis aries 76000.0 2 PMID:18436396 -3.1.1.79 * rattus norvegicus 160000.0 11 PMID:10694408;PMID:11277912;PMID:14576146;PMID:14725507;PMID:18824635;PMID:2029545;PMID:2557074;PMID:2988858;PMID:3196730;PMID:3675597;PMID:3708011;PMID:9781328 -3.1.1.79 * streptomyces coelicolor 38600.0 2 PMID:19321519 -3.1.1.79 * sus scrofa 84000.0 1 PMID:14725507;PMID:2029545;PMID:2988858;PMID:3196730;PMID:3708011 -3.1.1.79 * uncultured bacterium 79100.0 1 PMID:27328716 -3.1.1.8 * alectoris rufa 340000.0 2 PMID:8461052 -3.1.1.8 * columba livia 340000.0 2 PMID:8461052 -3.1.1.8 * diopatra neapolitana 150000.0 1 PMID:27777085 -3.1.1.8 * equus caballus 440000.0 6 PMID:10718335;PMID:4735538;PMID:5009701 -3.1.1.8 * gallus gallus 440000.0 2 PMID:7407196 -3.1.1.8 * homo sapiens 366000.0 10 PMID:11368776;PMID:11856322;PMID:17768338;PMID:18602477;PMID:7027759 -3.1.1.8 * oryctolagus cuniculus 78300.0 4 PMID:7391074 -3.1.1.8 * ovis aries 290000.0 1 PMID:8343984 -3.1.1.8 * platyrrhini 74000.0 1 PMID:9803663 -3.1.1.8 * pseudomonas aeruginosa 59000.0 1 PMID:5141 -3.1.1.8 * sus scrofa 370000.0 3 PMID:29908755;PMID:7027759 -3.1.1.80 * rauvolfia serpentina 33000.0 1 PMID:2955586 -3.1.1.80 * rauvolfia verticillata 40000.0 1 PMID:16133216 -3.1.1.81 * alicyclobacillus acidoterrestris 32500.0 1 PMID:28777091 -3.1.1.81 * arthrobacter sp. 36000.0 2 PMID:12777494 -3.1.1.81 * bacillus cereus 28000.0 1 PMID:24233057;PMID:36209456 -3.1.1.81 * bacillus licheniformis 28000.0 1 PMID:25060960 -3.1.1.81 * bacillus mycoides 28000.0 1 PMID:30310963 -3.1.1.81 * bacillus sp. b10 28000.0 1 PMID:20872263 -3.1.1.81 * bacillus sp. b6 28000.0 1 PMID:20872263 -3.1.1.81 * bacillus thuringiensis 28000.0 1 PMID:24233057;PMID:36209456 -3.1.1.81 * bacillus thuringiensis serovar kurstaki 29000.0 2 PMID:15895999 -3.1.1.81 * enterobacter sp. cs66 29000.0 1 PMID:27911925;PMID:29518220 -3.1.1.81 * flagellimonas olearia 31000.0 1 PMID:25398866 -3.1.1.81 * klebsiella aerogenes 30000.0 1 PMID:26432367;PMID:30391237;PMID:31261836 -3.1.1.81 * kurthia huakuii 50000.0 1 PMID:29662232 -3.1.1.81 * kushneria avicenniae 35000.0 1 PMID:26092757 -3.1.1.81 * lysinibacillus sp. 29000.0 1 PMID:27911925;PMID:29518220 -3.1.1.81 * microbacterium testaceum 74000.0 1 PMID:20173075 -3.1.1.81 * peribacillus simplex 28000.0 1 PMID:24233057;PMID:36209456 -3.1.1.81 * saccharococcus caldoxylosilyticus 32000.0 2 PMID:21897031;PMID:27599858 -3.1.1.81 * saccharolobus solfataricus 34000.0 1 PMID:21183649 -3.1.1.81 * salinicola salarius 30000.0 2 PMID:26432367;PMID:30391237;PMID:31261836 -3.1.1.81 * sphingopyxis sp. eg6 30000.0 1 PMID:26432367;PMID:30391237;PMID:31261836 -3.1.1.81 * sphingopyxis sp. fd7 30000.0 1 PMID:26432367;PMID:30391237;PMID:31261836 -3.1.1.81 * tenacibaculum sp. 20j 35000.0 1 PMID:26092757 -3.1.1.81 * uncultured bacterium 29600.0 1 PMID:29067011 -3.1.1.82 * chenopodium album 105000.0 2 * -3.1.1.82 * chlamydomonas reinhardtii 170000.0 3 PMID:11382812 -3.1.1.82 * raphanus sativus 113000.0 6 PMID:16228561;PMID:16384908;PMID:18846292 -3.1.1.83 * rhodococcus erythropolis 35000.0 1 PMID:11157238 -3.1.1.84 * homo sapiens 80000.0 2 PMID:9169443 -3.1.1.84 * rhodococcus sp. (in: high g+c gram-positive bacteria) 127000.0 5 PMID:10698749;PMID:21890748;PMID:21990608;PMID:22404344 -3.1.1.84 * stenotrophomonas maltophilia 410000.0 3 PMID:1551831 -3.1.1.85 * escherichia coli 28510.0 2 PMID:11904168;PMID:12527210 -3.1.1.85 * mycolicibacterium smegmatis 60000.0 1 PMID:35816546 -3.1.1.85 * neisseria meningitidis 28000.0 2 PMID:11904168;PMID:12527210 -3.1.1.85 * pseudomonas aeruginosa 25000.0 1 PMID:36689471 -3.1.1.85 * serratia marcescens 28000.0 1 PMID:11904168;PMID:12527210 -3.1.1.86 * aspergillus aculeatinus 27800.0 1 PMID:33838820 -3.1.1.86 * aspergillus aculeatus 26350.0 1 PMID:7592973 -3.1.1.86 * aspergillus sojae 33000.0 4 * -3.1.1.86 * paenibacillus polymyxa 44500.0 1 * -3.1.1.87 * sphingopyxis macrogoltabida 52400.0 1 PMID:19922747 -3.1.1.88 * aspergillus niger 56000.0 1 PMID:31835049 -3.1.1.88 * bacillus cereus 61000.0 3 PMID:8357241 -3.1.1.88 * brucella anthropi 25000.0 1 PMID:22579404 -3.1.1.88 * escherichia coli 30800.0 1 PMID:22409882 -3.1.1.88 * sphingobium faniae 31000.0 1 PMID:31835049;PMID:33461010 -3.1.1.88 * sphingobium sp. 31000.0 3 PMID:19581484 -3.1.1.88 * sphingobium wenxiniae 31000.0 1 PMID:25917649 -3.1.1.88 * uncultured microorganism 35000.0 1 PMID:28893251 -3.1.1.89 * homo sapiens 44000.0 2 PMID:10318862 -3.1.1.89 * sus scrofa 45000.0 1 PMID:14748741 -3.1.1.90 * danio rerio 61000.0 1 PMID:21235714 -3.1.1.93 * homo sapiens 28000.0 1 PMID:22294686 -3.1.1.95 * streptomyces purpurascens 33000.0 3 PMID:11004563 -3.1.1.96 * arabidopsis thaliana 34726.0 1 PMID:17251192 -3.1.1.96 * pyrococcus abyssi 35000.0 3 PMID:16844682 -3.1.1.96 * saccharolobus solfataricus 30000.0 2 PMID:16844682 -3.1.1.96 * synechocystis sp. 29258.0 1 PMID:19332551 -3.1.1.96 * thermus thermophilus 32000.0 2 * -3.1.1.98 * homo sapiens 54000.0 1 PMID:29937983 -3.1.11.1 * escherichia coli 140000.0 8 PMID:11400432;PMID:18219121;PMID:3539937;PMID:3893543;PMID:4600144;PMID:4607228;PMID:6343375 -3.1.11.1 * oryza sativa 92200.0 1 PMID:18231866 -3.1.11.1 * pyrococcus furiosus 73400.0 2 PMID:23505520 -3.1.11.1 * pyrococcus horikoshii 75000.0 1 PMID:25084386 -3.1.11.2 * escherichia coli 58000.0 2 PMID:11305928;PMID:794874 -3.1.11.2 * homo sapiens 95000.0 1 PMID:16687656 -3.1.11.2 * saccharolobus solfataricus 100000.0 2 PMID:8132506;PMID:8703921 -3.1.11.3 * escherichia coli 28000.0 3 PMID:10454600;PMID:4928646 -3.1.11.3 * lambdavirus lambda 28000.0 3 PMID:10454600;PMID:4928646 -3.1.11.3 * oryctolagus cuniculus 42000.0 1 * -3.1.11.3 * saccharomyces cerevisiae 70000.0 1 PMID:2050153 -3.1.11.5 * alcaligenes faecalis 220000.0 1 PMID:7215356 -3.1.11.5 * bacillus subtilis 308000.0 11 PMID:1096951;PMID:11929535;PMID:6263614 -3.1.11.5 * escherichia coli 655000.0 17 PMID:1618858;PMID:1864499;PMID:2154479;PMID:32597964;PMID:33085588;PMID:3526335;PMID:3537960;PMID:3537961;PMID:4552016;PMID:4916924 -3.1.11.5 * haemophilus influenzae 290000.0 4 * -3.1.11.5 * pasteurella multocida 330000.0 1 PMID:32597964;PMID:33085588 -3.1.11.5 * proteus mirabilis 330000.0 1 PMID:32597964;PMID:33085588 -3.1.11.5 * pseudomonas aeruginosa 330000.0 2 PMID:32597964;PMID:33085588 -3.1.11.5 * saccharomyces cerevisiae 99000.0 1 PMID:3286646 -3.1.11.5 * shewanella putrefaciens 330000.0 1 PMID:32597964;PMID:33085588 -3.1.11.5 * strongylocentrotus intermedius 450000.0 1 * -3.1.11.5 * vibrio cholerae 330000.0 1 PMID:32597964;PMID:33085588 -3.1.11.5 * vibrio vulnificus 330000.0 1 PMID:32597964;PMID:33085588 -3.1.11.5 * yersinia pestis 330000.0 1 PMID:32597964;PMID:33085588 -3.1.11.6 * escherichia coli 105000.0 4 PMID:1620628;PMID:4602029;PMID:6284744;PMID:6350262 -3.1.12.1 * saccharolobus solfataricus 170000.0 2 PMID:23056615 -3.1.13.1 * caenorhabditis elegans 67000.0 1 PMID:15210334 -3.1.13.1 * chelonia mydas 13000.0 2 PMID:16947078 -3.1.13.1 * chlamydomonas sp. 67000.0 1 PMID:15210334 -3.1.13.1 * drosophila sp. (in: flies) 67000.0 1 PMID:15210334 -3.1.13.1 * embryophyta 67000.0 1 PMID:15210334 -3.1.13.1 * escherichia coli 90000.0 5 PMID:15210334;PMID:336625;PMID:364422;PMID:4867942;PMID:8557629 -3.1.13.1 * haloferax volcanii 67000.0 1 PMID:15210334 -3.1.13.1 * homo sapiens 67000.0 3 PMID:15210334;PMID:7989354 -3.1.13.1 * mammalia 67000.0 1 PMID:15210334 -3.1.13.1 * rattus norvegicus 92000.0 4 PMID:2982411;PMID:758956 -3.1.13.1 * saccharomyces cerevisiae 175000.0 3 PMID:11586897;PMID:15210334 -3.1.13.1 * streptomyces coelicolor 67000.0 1 PMID:15210334 -3.1.13.1 * synechocystis sp. 67000.0 1 PMID:15210334 -3.1.13.1 * uncultured gammaproteobacteria bacterium 67000.0 1 PMID:15210334 -3.1.13.2 * hepatitis b virus 20000.0 1 PMID:8955090 -3.1.13.2 * human immunodeficiency virus 1 15000.0 1 PMID:1710580 -3.1.13.2 * human spumaretrovirus 19000.0 3 PMID:22325739;PMID:22962864 -3.1.13.2 * moloney murine leukemia virus 80000.0 2 PMID:18261820;PMID:46925 -3.1.13.2 * sulfurisphaera tokodaii 18000.0 3 PMID:22389131 -3.1.13.3 * bartonella birtlesii 24000.0 1 PMID:22262096 -3.1.13.3 * colwellia psychrerythraea 36000.0 1 PMID:30804410 -3.1.13.3 * escherichia coli 38000.0 3 PMID:18023590;PMID:240824;PMID:9573169 -3.1.13.3 * homo sapiens 24576.0 1 PMID:18023590 -3.1.13.3 * metagenome 41000.0 1 PMID:31420950 -3.1.13.3 * mycolicibacterium smegmatis 42970.0 2 PMID:18023590;PMID:36244449 -3.1.13.4 * bos taurus 220000.0 5 PMID:10801819;PMID:6246077 -3.1.13.4 * homo sapiens 290000.0 19 PMID:14583602;PMID:17391638;PMID:17624302;PMID:18763168;PMID:19103158;PMID:19472977;PMID:20628353;PMID:21741754;PMID:25239613;PMID:26772900;PMID:9736620 -3.1.13.4 * mycobacterium marinum 38460.0 2 PMID:24704253 -3.1.13.4 * saccharomyces cerevisiae 161000.0 3 PMID:1339314;PMID:8550599 -3.1.13.4 * xenopus sp. 74000.0 1 PMID:9736620 -3.1.13.5 * escherichia coli 60000.0 2 PMID:342522;PMID:6263885 -3.1.14.1 * aspergillus flavipes 40000.0 1 * -3.1.14.1 * rhodotorula glutinis 58900.0 2 * -3.1.14.1 * schizosaccharomyces pombe 38000.0 1 PMID:11872168 -3.1.14.1 * trichoderma viride 27500.0 1 PMID:1794979 -3.1.14.1 * ustilago sphaerogena 29000.0 4 PMID:5079892 -3.1.15.1 * bothrops alternatus 105000.0 1 PMID:12638651 -3.1.15.1 * bothrops atrox 134000.0 1 PMID:4348125 -3.1.15.1 * crotalus adamanteus 140000.0 2 PMID:205220;PMID:9202136 -3.1.15.1 * crotalus atrox 112000.0 1 PMID:205220 -3.1.15.1 * daboia siamensis 150000.0 2 * -3.1.15.1 * macrovipera lebetinus 120000.0 3 PMID:25079051 -3.1.15.1 * vipera aspis 150000.0 1 PMID:196525 -3.1.15.1 * walterinnesia aegyptia 158000.0 1 PMID:21660866 -3.1.16.1 * bos taurus 160000.0 4 PMID:6289292;PMID:9515059 -3.1.16.1 * cavia porcellus 125000.0 1 PMID:4377208 -3.1.16.1 * plasmodium falciparum 75000.0 1 PMID:17928073 -3.1.16.1 * plasmodium yoelii 54500.0 1 PMID:17928073 -3.1.16.1 * rattus norvegicus 170000.0 1 PMID:4377208 -3.1.16.1 * trypanosoma brucei 158000.0 3 PMID:17077271 -3.1.2.1 * ascaris suum 232000.0 1 * -3.1.2.1 * mus musculus 322000.0 1 PMID:23709691 -3.1.2.1 * rattus norvegicus 340000.0 15 PMID:11322891;PMID:16476568;PMID:2857646;PMID:6102995;PMID:6132615;PMID:9939 -3.1.2.1 * saccharomyces cerevisiae 58370.0 1 PMID:1970569 -3.1.2.12 * [candida] boidinii 64000.0 3 PMID:7397203 -3.1.2.12 * arabidopsis thaliana 66000.0 4 PMID:11888210;PMID:16626737 -3.1.2.12 * homo sapiens 58200.0 5 PMID:20209484;PMID:4436331;PMID:6276656;PMID:7484406 -3.1.2.12 * kloeckera sp. 58000.0 2 PMID:7188860 -3.1.2.12 * pseudoalteromonas haloplanktis 60000.0 3 PMID:20209484;PMID:21107664;PMID:4436331;PMID:6276656 -3.1.2.12 * saccharomyces cerevisiae 67800.0 4 PMID:10427036;PMID:18707125 -3.1.2.12 * shewanella frigidimarina 62300.0 1 PMID:31426813 -3.1.2.13 * homo sapiens 18000.0 1 PMID:457667 -3.1.2.14 * allium ampeloprasum 84000.0 2 PMID:7622515 -3.1.2.14 * arachis hypogaea 72000.0 1 PMID:23093853 -3.1.2.14 * brassica napus 41980.0 2 PMID:8251630 -3.1.2.14 * brassica rapa subsp. oleifera 72000.0 2 * -3.1.2.14 * camelina sativa 34800.0 2 PMID:25212866 -3.1.2.14 * carthamus tinctorius 37250.0 1 PMID:16653193 -3.1.2.14 * cinnamomum longepaniculatum 61000.0 1 PMID:24460945 -3.1.2.14 * cucurbita moschata 59000.0 4 PMID:1391766 -3.1.2.14 * cuphea lanceolata 53000.0 2 PMID:24178501 -3.1.2.14 * diploknema butyracea 45000.0 1 * -3.1.2.14 * elaeis sp. 66000.0 1 PMID:11171146 -3.1.2.14 * helianthus annuus 41200.0 3 PMID:15841386;PMID:24327259 -3.1.2.14 * jatropha curcas 48080.0 1 PMID:19671567 -3.1.2.14 * lindera communis 40500.0 1 PMID:24631366 -3.1.2.14 * macadamia tetraphylla 46200.0 2 PMID:21071236 -3.1.2.14 * mangifera indica 78000.0 2 PMID:21130480 -3.1.2.14 * persea americana 80000.0 1 PMID:30409 -3.1.2.14 * ricinus communis 46500.0 4 PMID:20382402 -3.1.2.16 * rubrivivax gelatinosus 14300.0 2 PMID:7460909 -3.1.2.17 * rattus norvegicus 35000.0 1 PMID:6885824 -3.1.2.18 * rattus norvegicus 240000.0 1 PMID:2570608 -3.1.2.19 * rattus norvegicus 100000.0 1 PMID:2570608 -3.1.2.2 * anas platyrhynchos 56300.0 1 PMID:3882056 -3.1.2.2 * arabidopsis thaliana 196000.0 1 PMID:14660652 -3.1.2.2 * bos taurus 41000.0 2 PMID:3674876;PMID:8631842;PMID:9163348 -3.1.2.2 * buckleyzyma aurantiaca 85000.0 2 PMID:11279019 -3.1.2.2 * cereibacter sphaeroides 120000.0 4 PMID:2872920 -3.1.2.2 * columba sp. 500000.0 1 PMID:238978 -3.1.2.2 * diutina rugosa 40000.0 1 PMID:6122441;PMID:7334001;PMID:7744868;PMID:8837745 -3.1.2.2 * escherichia coli 123000.0 6 PMID:1645722;PMID:235694;PMID:4554913;PMID:4871199 -3.1.2.2 * euglena gracilis 37000.0 1 PMID:2857556 -3.1.2.2 * homo sapiens 100000.0 8 PMID:10092594;PMID:10578051;PMID:10807905;PMID:11785945;PMID:2570608;PMID:3674876;PMID:38776;PMID:39618;PMID:5042454;PMID:6122441;PMID:7334001;PMID:7744868;PMID:8631842;PMID:8837745;PMID:9163348 -3.1.2.2 * lathyrus oleraceus 140000.0 3 PMID:6146527 -3.1.2.2 * mus musculus 48000.0 1 PMID:10383425 -3.1.2.2 * mycolicibacterium phlei 10500.0 1 PMID:4572728 -3.1.2.2 * mycolicibacterium smegmatis 42000.0 4 PMID:3674876;PMID:6122441;PMID:7334001;PMID:7744868;PMID:8631842;PMID:8837745;PMID:9163348 -3.1.2.2 * oryctolagus cuniculus 170000.0 2 PMID:6498215 -3.1.2.2 * pseudomonas aeruginosa 55000.0 1 PMID:41836 -3.1.2.2 * rattus norvegicus 150000.0 36 PMID:10578051;PMID:10807905;PMID:11785945;PMID:11914918;PMID:2570608;PMID:2868711;PMID:3674876;PMID:37085;PMID:38776;PMID:39618;PMID:5042454;PMID:6105869;PMID:6108217;PMID:6115749;PMID:6122441;PMID:7334001;PMID:7607256;PMID:7722521;PMID:7744868;PMID:7906114;PMID:7913034;PMID:8100522;PMID:8105781;PMID:8579357;PMID:8631842;PMID:8837745;PMID:9163348 -3.1.2.2 * sus scrofa 300000.0 1 PMID:35538 -3.1.2.20 * alcaligenes faecalis 22000.0 1 PMID:16704412 -3.1.2.20 * anas platyrhynchos 56300.0 1 PMID:3882056 -3.1.2.20 * arabidopsis thaliana 196000.0 2 PMID:14660652;PMID:23288899 -3.1.2.20 * bos taurus 41000.0 2 PMID:3674876;PMID:8631842;PMID:9163348 -3.1.2.20 * buckleyzyma aurantiaca 85000.0 2 PMID:11279019 -3.1.2.20 * cereibacter sphaeroides 120000.0 4 PMID:2872920 -3.1.2.20 * columba sp. 500000.0 1 PMID:238978 -3.1.2.20 * diutina rugosa 40000.0 1 PMID:6122441;PMID:7334001;PMID:7744868;PMID:8837745 -3.1.2.20 * escherichia coli 123000.0 8 PMID:1645722;PMID:18247525;PMID:18576672;PMID:235694;PMID:4554913;PMID:4871199 -3.1.2.20 * escherichia coli k-12 54400.0 1 PMID:19193103 -3.1.2.20 * euglena gracilis 37000.0 1 PMID:2857556 -3.1.2.20 * haemophilus influenzae 17000.0 2 PMID:18247525;PMID:18260643 -3.1.2.20 * homo sapiens 100000.0 8 PMID:10092594;PMID:10578051;PMID:10807905;PMID:11785945;PMID:2570608;PMID:3674876;PMID:38776;PMID:39618;PMID:5042454;PMID:6122441;PMID:7334001;PMID:7744868;PMID:8631842;PMID:8837745;PMID:9163348 -3.1.2.20 * lathyrus oleraceus 140000.0 3 PMID:6146527 -3.1.2.20 * mus musculus 112000.0 3 PMID:10383425;PMID:19405909;PMID:22993230 -3.1.2.20 * mycolicibacterium phlei 10500.0 1 PMID:4572728 -3.1.2.20 * mycolicibacterium smegmatis 42000.0 4 PMID:3674876;PMID:6122441;PMID:7334001;PMID:7744868;PMID:8631842;PMID:8837745;PMID:9163348 -3.1.2.20 * oryctolagus cuniculus 170000.0 2 PMID:6498215 -3.1.2.20 * pseudomonas aeruginosa 55000.0 1 PMID:41836 -3.1.2.20 * rattus norvegicus 150000.0 33 PMID:10578051;PMID:10807905;PMID:11785945;PMID:2570608;PMID:2868711;PMID:3674876;PMID:37085;PMID:38776;PMID:39618;PMID:5042454;PMID:6105869;PMID:6108217;PMID:6115749;PMID:6122441;PMID:7334001;PMID:7607256;PMID:7722521;PMID:7744868;PMID:7906114;PMID:7913034;PMID:8100522;PMID:8105781;PMID:8579357;PMID:8631842;PMID:8837745;PMID:9163348 -3.1.2.20 * saccharomyces cerevisiae 43400.0 1 PMID:16490786 -3.1.2.20 * streptomyces sp. 35000.0 2 PMID:18836004 -3.1.2.20 * sus scrofa 300000.0 1 PMID:35538 -3.1.2.21 * umbellularia californica 42000.0 2 PMID:1898097;PMID:8785117 -3.1.2.22 * bos taurus 37000.0 1 PMID:7901201 -3.1.2.22 * homo sapiens 32000.0 2 PMID:19439193;PMID:33707782 -3.1.2.22 * mus musculus 37000.0 1 PMID:11136716 -3.1.2.22 * schizosaccharomyces pombe 101000.0 2 PMID:15075260 -3.1.2.23 * aromatoleum evansii 62000.0 2 PMID:18542924 -3.1.2.23 * pseudomonas sp. 66000.0 3 PMID:1610806;PMID:7765837 -3.1.2.25 * penicillium chrysogenum 25000.0 1 PMID:237213 -3.1.2.27 * mus musculus 70000.0 3 PMID:11673457 -3.1.2.28 * arabidopsis thaliana 62500.0 2 PMID:24100308 -3.1.2.28 * synechocystis sp. 77400.0 3 PMID:19321747;PMID:24100308 -3.1.2.3 * sus scrofa 100000.0 1 * -3.1.2.30 * cereibacter sphaeroides 80000.0 2 PMID:20047909 -3.1.2.4 * homo sapiens 39398.0 5 PMID:10989434;PMID:16019269;PMID:8824301 -3.1.2.4 * rattus norvegicus 36000.0 1 PMID:10989434;PMID:8188708 -3.1.2.6 * aloe vera 27000.0 1 PMID:2076100 -3.1.2.6 * arabidopsis thaliana 29000.0 3 PMID:8550579;PMID:9428743 -3.1.2.6 * bos taurus 23000.0 2 * -3.1.2.6 * brassica juncea 36520.0 1 PMID:16153601 -3.1.2.6 * cyberlindnera mrakii 24000.0 2 * -3.1.2.6 * homo sapiens 29200.0 6 PMID:4745654;PMID:8504817;PMID:8550579;PMID:93000 -3.1.2.6 * leishmania donovani 46000.0 3 PMID:16159313 -3.1.2.6 * leishmania infantum 32000.0 1 PMID:16880563 -3.1.2.6 * mus musculus 29500.0 1 PMID:7350914 -3.1.2.6 * oryza sativa 28560.0 1 PMID:25039836 -3.1.2.6 * plasmodium falciparum 31800.0 3 PMID:15843146;PMID:19663684 -3.1.2.6 * rattus norvegicus 30000.0 5 PMID:3814608;PMID:496013;PMID:93000 -3.1.2.6 * saccharomyces cerevisiae 32325.0 5 PMID:10600466;PMID:21310260 -3.1.2.6 * trypanosoma brucei 32507.0 5 PMID:14976196 -3.1.2.6 * zea mays 26000.0 2 PMID:18533364;PMID:2630289 -3.1.2.7 * saccharomyces cerevisiae 56000.0 3 * -3.1.21.1 * aquarana catesbeiana 40000.0 1 PMID:11439097 -3.1.21.1 * badhamia polycephala 17000.0 1 PMID:6244270 -3.1.21.1 * basidiobolus haptosporus 41000.0 2 PMID:10931196 -3.1.21.1 * bos taurus 34000.0 4 PMID:10092662;PMID:3782104;PMID:6230231;PMID:8428592;PMID:9469931 -3.1.21.1 * bufo japonicus 40000.0 1 PMID:11439097 -3.1.21.1 * cavia porcellus 33000.0 1 PMID:6274408 -3.1.21.1 * choristoneura fumiferana 23000.0 1 PMID:11804797 -3.1.21.1 * coprinopsis cinerea 22000.0 3 PMID:2839339 -3.1.21.1 * corynebacterium diphtheriae 61000.0 1 PMID:21889551 -3.1.21.1 * cynops pyrrhogaster 40000.0 2 PMID:11439097 -3.1.21.1 * cyprinus carpio 32000.0 2 PMID:12761174;PMID:486413 -3.1.21.1 * gallus gallus 30882.0 3 PMID:12739897 -3.1.21.1 * helicobacter pylori 17000.0 1 PMID:15090498 -3.1.21.1 * heterodontus japonicus 33000.0 1 PMID:15560784 -3.1.21.1 * homo sapiens 80000.0 10 PMID:10092662;PMID:11141064;PMID:115887;PMID:15236597;PMID:15521815;PMID:2277032;PMID:23831;PMID:3782104;PMID:413831;PMID:6204972;PMID:6230231;PMID:8428592 -3.1.21.1 * hordeum vulgare 32000.0 1 PMID:8749309 -3.1.21.1 * mus musculus 37000.0 4 PMID:19154352 -3.1.21.1 * oreochromis mossambicus 30000.0 1 PMID:9395327 -3.1.21.1 * oryctolagus cuniculus 35000.0 1 PMID:16487071 -3.1.21.1 * ovis aries 31000.0 1 PMID:486413 -3.1.21.1 * rattus norvegicus 32000.0 1 PMID:16487071;PMID:6230231 -3.1.21.1 * rattus sp. 36000.0 5 PMID:10092662;PMID:16487071;PMID:3782104;PMID:4093446;PMID:6230231;PMID:7074091;PMID:8428592;PMID:8749309 -3.1.21.1 * streptococcus suis 108000.0 1 PMID:14742520 -3.1.21.1 * streptomyces thermovulgaris 22400.0 1 * -3.1.21.1 * sus scrofa 345000.0 4 PMID:10092662;PMID:16487071;PMID:16514189;PMID:3782104;PMID:6230231;PMID:8428592 -3.1.21.1 * syncephalastrum racemosum 28000.0 1 PMID:8489265 -3.1.21.1 * vibrio cholerae serotype o1 25000.0 1 PMID:15718143 -3.1.21.10 * arabidopsis thaliana 78000.0 5 PMID:19339504;PMID:25037209 -3.1.21.10 * bacillus phage spp1 54000.0 3 PMID:23119018 -3.1.21.10 * bacillus pumilus 109000.0 2 PMID:17392342 -3.1.21.10 * bacillus subtilis 25000.0 3 PMID:14701911;PMID:18684995 -3.1.21.10 * escherichia coli 40000.0 3 PMID:1661673;PMID:8057369;PMID:8665955 -3.1.21.10 * homo sapiens 140000.0 3 PMID:18310322;PMID:23166748 -3.1.21.10 * mycobacterium tuberculosis 50000.0 2 PMID:19072585;PMID:26817626 -3.1.21.10 * pyrococcus furiosus 14300.0 1 PMID:11005813 -3.1.21.10 * saccharolobus solfataricus 16010.0 1 PMID:10736227 -3.1.21.10 * saccharomyces cerevisiae 106400.0 7 PMID:1661673;PMID:18281703;PMID:2556268;PMID:8665955 -3.1.21.10 * schizosaccharomyces pombe 33000.0 2 PMID:9343409;PMID:9857040 -3.1.21.2 * mycobacterium tuberculosis 33600.0 3 PMID:23936515;PMID:26043425 -3.1.21.2 * tequatrovirus t4 16000.0 1 PMID:20156453 -3.1.21.2 * thermotoga maritima 32400.0 2 PMID:10217775;PMID:20054139 -3.1.21.2 * thermus thermophilus 29000.0 1 PMID:16782061 -3.1.21.3 * escherichia coli 431000.0 15 PMID:18164032;PMID:18535150;PMID:22493743;PMID:8632480 -3.1.21.3 * synthetic construct 18450.0 2 PMID:19336410 -3.1.21.3 * vibrio vulnificus 60000.0 1 PMID:23090406 -3.1.21.3 * vibrio vulnificus yj016 95000.0 4 PMID:19625490;PMID:20054126 -3.1.21.4 * [bacillus] caldolyticus 25000.0 1 * -3.1.21.4 * bacillus amyloliquefaciens 22000.0 1 * -3.1.21.4 * bacillus sp. (in: firmicutes) 70800.0 1 PMID:18835275 -3.1.21.4 * bacillus subtilis 68000.0 8 PMID:12549825;PMID:1721700;PMID:2997708 -3.1.21.4 * citrobacter freundii 27000.0 1 PMID:22753027 -3.1.21.4 * escherichia coli 67000.0 5 PMID:16497303;PMID:18642930;PMID:24878924 -3.1.21.4 * geobacillus stearothermophilus 26000.0 1 * -3.1.21.4 * haemophilus haemolyticus 24000.0 1 * -3.1.21.4 * haemophilus influenzae 70000.0 2 PMID:15805123 -3.1.21.4 * haemophilus parainfluenzae 40000.0 1 * -3.1.21.4 * lysinibacillus sphaericus 35000.0 1 PMID:710408 -3.1.21.4 * methylophilus methylotrophus 105100.0 1 PMID:18931376 -3.1.21.4 * moraxella cuniculi 51000.0 2 PMID:11267775 -3.1.21.4 * priestia megaterium 60000.0 2 PMID:3036510;PMID:6091684 -3.1.21.4 * saccharolobus islandicus 40000.0 1 PMID:16896525 -3.1.21.4 * streptococcus pneumoniae 70000.0 2 * -3.1.21.4 * thermus scotoductus 594000.0 1 PMID:24634443 -3.1.21.4 * thermus thermophilus 95000.0 1 * -3.1.21.5 * escherichia coli 407000.0 12 PMID:11178902;PMID:11557806;PMID:24510100 -3.1.21.5 * neisseria gonorrhoeae 77500.0 1 PMID:19758331 -3.1.21.5 * prophage p1 409000.0 3 PMID:11178902 -3.1.21.5 * providencia stuartii 235700.0 3 PMID:24510100 -3.1.21.6 * bombyx mori 22000.0 1 PMID:17537809 -3.1.21.6 * mycolicibacterium smegmatis 43000.0 1 PMID:16584627 -3.1.21.7 * bos taurus 53000.0 2 PMID:833111 -3.1.21.7 * escherichia coli 27000.0 2 PMID:16001;PMID:6246346 -3.1.21.7 * homo sapiens 55000.0 3 PMID:25195743 -3.1.21.7 * pyrococcus furiosus 23580.0 1 PMID:26116888 -3.1.21.7 * tequatrovirus t4 19000.0 4 PMID:1888726;PMID:8597580 -3.1.21.7 * trypanosoma brucei brucei 34922.0 1 PMID:28819113 -3.1.22.1 * bos taurus 41000.0 1 PMID:6257355 -3.1.22.1 * burkholderia thailandensis 40301.0 1 PMID:28369538 -3.1.22.1 * chlamys islandica 42000.0 2 PMID:16426884 -3.1.22.1 * cricetulus griseus 28000.0 1 PMID:8424678 -3.1.22.1 * euglena gracilis 45000.0 1 PMID:11959034 -3.1.22.1 * homo sapiens 45000.0 8 PMID:11906178;PMID:1540651;PMID:1761047;PMID:4334998;PMID:6248503;PMID:9714827;PMID:9862463 -3.1.22.1 * mammalia 40000.0 1 PMID:6086935 -3.1.22.1 * mytilus galloprovincialis 48000.0 2 * -3.1.22.1 * oncorhynchus tshawytscha 38000.0 1 * -3.1.22.1 * ophiocordyceps sinensis 34000.0 1 PMID:15469735 -3.1.22.1 * rattus sp. 36000.0 2 PMID:4334998;PMID:6248503;PMID:6630162 -3.1.22.1 * sus scrofa 46500.0 11 PMID:19292869;PMID:2909240;PMID:9584202;PMID:9714827 -3.1.22.5 * escherichia coli 49000.0 1 * -3.1.25.1 * homo sapiens 26700.0 1 PMID:15707971 -3.1.25.1 * micrococcus luteus 30340.0 4 PMID:7559510;PMID:893408;PMID:9012829 -3.1.25.1 * mus musculus 26700.0 1 PMID:15707971 -3.1.25.1 * tequatrovirus t4 18000.0 5 PMID:164454;PMID:2914925;PMID:6246342;PMID:6265906;PMID:6277906 -3.1.26.1 * badhamia polycephala 25000.0 2 PMID:563399 -3.1.26.10 * ceratitis capitata 34000.0 2 PMID:1627176;PMID:3569265 -3.1.26.10 * homo sapiens 26000.0 1 PMID:12210760 -3.1.26.10 * saccharomyces cerevisiae 29000.0 1 PMID:9366271 -3.1.26.11 * arabidopsis thaliana 79000.0 2 PMID:12032089 -3.1.26.11 * aspergillus nidulans 160000.0 1 PMID:9144538 -3.1.26.11 * drosophila melanogaster 92000.0 4 PMID:14715923;PMID:15935379 -3.1.26.11 * homo sapiens 98000.0 7 PMID:16361254;PMID:19526060;PMID:23874404 -3.1.26.11 * methanocaldococcus jannaschii 45000.0 1 PMID:12032089 -3.1.26.11 * pyrococcus furiosus 37000.0 1 PMID:18437358 -3.1.26.11 * schizosaccharomyces pombe 90600.0 2 PMID:19555350 -3.1.26.11 * triticum aestivum 165000.0 5 PMID:10684660;PMID:12032089 -3.1.26.12 * arabidopsis thaliana 680000.0 2 PMID:18441049 -3.1.26.12 * escherichia coli 464000.0 11 PMID:14636052;PMID:15779893;PMID:16237448;PMID:18976283;PMID:24766456;PMID:8412702;PMID:8415644;PMID:9106202 -3.1.26.12 * photobacterium angustum s14 122600.0 1 PMID:19345289 -3.1.26.12 * rhizobium leguminosarum bv. viciae 180000.0 1 PMID:19727520 -3.1.26.12 * saccharolobus solfataricus 23700.0 2 PMID:18482976 -3.1.26.12 * vibrio vulnificus 170000.0 2 PMID:21046401 -3.1.26.13 * human immunodeficiency virus 110000.0 1 PMID:2468665 -3.1.26.13 * human immunodeficiency virus 1 66000.0 2 PMID:20376302 -3.1.26.13 * moloney murine leukemia virus 71000.0 1 PMID:2410413 -3.1.26.3 * arabidopsis thaliana 110000.0 4 PMID:18158302 -3.1.26.3 * bacillus subtilis 38100.0 2 PMID:18363798 -3.1.26.3 * escherichia coli 103000.0 7 PMID:11305928;PMID:11586889;PMID:11997024;PMID:350582;PMID:932008 -3.1.26.3 * escherichia coli k-12 56000.0 1 PMID:19478437 -3.1.26.3 * mus musculus 60000.0 1 PMID:6248530 -3.1.26.3 * paramecium bursaria chlorella virus-1 64000.0 2 PMID:14675626 -3.1.26.3 * rock bream iridovirus 31090.0 2 PMID:18641914 -3.1.26.3 * saccharomyces cerevisiae 110000.0 2 PMID:10943893 -3.1.26.3 * salmonella enterica subsp. enterica serovar typhimurium 44000.0 1 PMID:1101968 -3.1.26.3 * staphylococcus aureus 27900.0 1 PMID:19161850 -3.1.26.3 * trypanosoma brucei 57300.0 1 PMID:21810935 -3.1.26.4 * bos taurus 150000.0 14 PMID:1690146;PMID:2154245;PMID:279904;PMID:4516197;PMID:4709937;PMID:6177690;PMID:6251088 -3.1.26.4 * daucus carota 180000.0 2 PMID:447617 -3.1.26.4 * escherichia coli 40000.0 4 PMID:10788800;PMID:2172991;PMID:4572736 -3.1.26.4 * gallus gallus 120000.0 2 PMID:6292174 -3.1.26.4 * geobacillus stearothermophilus 36000.0 4 PMID:15502360;PMID:23937561 -3.1.26.4 * halobacterium salinarum 24000.0 1 PMID:23772368 -3.1.26.4 * homo sapiens 89000.0 3 PMID:1706718;PMID:31529068;PMID:7816613 -3.1.26.4 * human foamy virus 19000.0 2 PMID:22325739 -3.1.26.4 * leishmania donovani 53000.0 2 PMID:15978682 -3.1.26.4 * leishmania major 53000.0 2 PMID:15978682 -3.1.26.4 * mus musculus 110000.0 4 PMID:20823270;PMID:457685 -3.1.26.4 * mycosarcoma maydis 130000.0 1 PMID:4434992 -3.1.26.4 * pyrococcus furiosus 25300.0 1 PMID:12943689 -3.1.26.4 * rattus norvegicus 125000.0 7 PMID:29889;PMID:29890;PMID:4838988;PMID:718683 -3.1.26.4 * saccharomyces cerevisiae 110000.0 5 PMID:3049596;PMID:6295279 -3.1.26.4 * shewanella sp. 25000.0 1 PMID:16650002 -3.1.26.4 * sulfurisphaera tokodaii 16812.0 2 PMID:15520465 -3.1.26.4 * thermotoga maritima 27000.0 2 PMID:23937561 -3.1.26.4 * thermus thermophilus 21000.0 3 PMID:1315754;PMID:18848567;PMID:23523920 -3.1.26.4 * uncultured organism 24000.0 3 PMID:1315754;PMID:23523920 -3.1.26.4 * xenopus laevis 68000.0 4 PMID:7929207 -3.1.26.5 * aquifex aeolicus 77000.0 2 PMID:29073018;PMID:34180399 -3.1.26.5 * arabidopsis thaliana 21500.0 1 PMID:22641852 -3.1.26.5 * aspergillus nidulans 580000.0 18 PMID:8631344;PMID:9492290 -3.1.26.5 * bacillus subtilis 13000.0 1 PMID:17355991 -3.1.26.5 * chlamydomonas reinhardtii 100000.0 1 PMID:27133210 -3.1.26.5 * escherichia coli 260000.0 3 PMID:2199767;PMID:358197;PMID:6164392 -3.1.26.5 * homo sapiens 170000.0 17 PMID:11871657;PMID:19376274;PMID:20215441;PMID:9642109 -3.1.26.5 * hydrogenobacter thermophilus 356062.0 2 PMID:37806495 -3.1.26.5 * methanocaldococcus jannaschii 400000.0 2 PMID:11592398 -3.1.26.5 * methanothermobacter thermautotrophicus 400000.0 1 PMID:11592398 -3.1.26.5 * rattus norvegicus 263000.0 1 PMID:1605634 -3.1.26.5 * saccharolobus solfataricus 400000.0 1 PMID:2115885 -3.1.26.5 * saccharomyces cerevisiae 120000.0 13 PMID:11241345;PMID:11741968;PMID:12045094 -3.1.26.5 * solanum tuberosum 33000.0 2 * -3.1.26.5 * trypanosoma brucei 70000.0 1 PMID:11377745 -3.1.26.6 * coturnix japonica 45000.0 1 PMID:1009929 -3.1.26.6 * gallus gallus 45000.0 1 PMID:1009928 -3.1.26.8 * bacillus subtilis 15000.0 1 PMID:6432797 -3.1.26.9 * bizionia sp. 53000.0 1 PMID:16644192 -3.1.26.9 * ceratitis capitata 25000.0 2 PMID:3569265 -3.1.27.8 * bos taurus 52300.0 1 PMID:6246098 -3.1.27.8 * homo sapiens 28800.0 2 PMID:25195743 -3.1.3.1 * aeropyrum pernix 75000.0 2 PMID:17256119 -3.1.3.1 * anabaena sp. 70000.0 2 PMID:17156125;PMID:20632947 -3.1.3.1 * antarctic bacterium 68000.0 2 PMID:16593525 -3.1.3.1 * antarctic bacterium tab5 35860.0 1 PMID:18411226 -3.1.3.1 * aspergillus caespitosus 138000.0 4 PMID:14976719;PMID:17702460;PMID:19381476;PMID:19714811 -3.1.3.1 * bacillus licheniformis 124000.0 4 PMID:18641147;PMID:3794650;PMID:718947 -3.1.3.1 * bacillus sp. ok-1 110000.0 2 PMID:11571149;PMID:413579;PMID:9654126 -3.1.3.1 * badhamia polycephala 105000.0 2 PMID:17899011 -3.1.3.1 * bos taurus 81000.0 1 PMID:3968087 -3.1.3.1 * bubalus bubalis 194000.0 2 * -3.1.3.1 * burkholderia cenocepacia 57000.0 1 PMID:19376213 -3.1.3.1 * camelus bactrianus 49000.0 2 * -3.1.3.1 * candida tropicalis 50000.0 1 * -3.1.3.1 * cobetia marina 62000.0 3 PMID:10862903;PMID:15906116;PMID:25260971 -3.1.3.1 * cyberlindnera jadinii 135000.0 1 * -3.1.3.1 * debaryomyces hansenii 110000.0 1 PMID:413579 -3.1.3.1 * dictyostelium sp. 80000.0 1 PMID:12597899 -3.1.3.1 * dioszegia sp. 39000.0 1 PMID:29312954 -3.1.3.1 * echinococcus multilocularis 240000.0 2 PMID:1799967 -3.1.3.1 * escherichia coli 47029.0 2 PMID:6312783 -3.1.3.1 * gallus gallus 270000.0 5 * -3.1.3.1 * geobacillus stearothermophilus 32000.0 1 PMID:10334954 -3.1.3.1 * geobacillus thermodenitrificans 42150.0 1 PMID:18365148 -3.1.3.1 * haloarcula marismortui 160000.0 1 PMID:2123861 -3.1.3.1 * halobacterium salinarum 110000.0 3 PMID:20438737 -3.1.3.1 * halomonas sp. 108000.0 2 PMID:15973058;PMID:20883791 -3.1.3.1 * helicoverpa armigera 138000.0 7 PMID:16466860;PMID:17702460;PMID:19714811;PMID:20170658;PMID:23358911 -3.1.3.1 * heliothis virescens 59000.0 5 PMID:19552892 -3.1.3.1 * homo sapiens 494000.0 26 PMID:12109816;PMID:12232676;PMID:15177289;PMID:1815949;PMID:18422967;PMID:3954357;PMID:426769;PMID:5666467;PMID:8193673;PMID:857894;PMID:9473461 -3.1.3.1 * lysobacter enzymogenes 150000.0 3 * -3.1.3.1 * meriones unguiculatus 306000.0 2 PMID:1799967 -3.1.3.1 * mus musculus 86000.0 2 PMID:3478679 -3.1.3.1 * mycothermus thermophilus 162000.0 4 PMID:11687941 -3.1.3.1 * neurospora crassa 137000.0 5 PMID:10920432;PMID:17176763 -3.1.3.1 * nilaparvata lugens 62700.0 2 * -3.1.3.1 * oryctolagus cuniculus 72000.0 1 PMID:1989515 -3.1.3.1 * paramecium tetraurelia 66000.0 1 PMID:2155027 -3.1.3.1 * pasteurella multocida 72800.0 2 PMID:17156125;PMID:20632947 -3.1.3.1 * penicillium chrysogenum 58000.0 1 PMID:8958566 -3.1.3.1 * phaeodactylum tricornutum 148000.0 2 PMID:19714811;PMID:23358911 -3.1.3.1 * pinctada fucata 40000.0 1 * -3.1.3.1 * porphyromonas gingivalis 130000.0 2 PMID:2117573 -3.1.3.1 * prevotella intermedia 108000.0 2 PMID:11571149;PMID:9654126 -3.1.3.1 * pseudomonas aeruginosa 51000.0 2 PMID:8454193 -3.1.3.1 * pseudomonas sp. 100000.0 1 PMID:28756743 -3.1.3.1 * pyrococcus abyssi 54000.0 2 PMID:11571149;PMID:9654126 -3.1.3.1 * rattus norvegicus 163000.0 15 PMID:10449195;PMID:11381619;PMID:2065078;PMID:3472490;PMID:6787043;PMID:974105 -3.1.3.1 * rhizopus microsporus 120000.0 3 PMID:14976719;PMID:19381476 -3.1.3.1 * rhizopus microsporus var. microsporus 123000.0 1 * -3.1.3.1 * saccharococcus caldoxylosilyticus 51590.0 2 * -3.1.3.1 * saccharomyces cerevisiae 130000.0 4 PMID:2117573 -3.1.3.1 * saccharomyces pombe 70000.0 1 * -3.1.3.1 * schistosoma mansoni 120000.0 2 PMID:21483710 -3.1.3.1 * shewanella sp. t3-3 100000.0 1 PMID:28756743 -3.1.3.1 * sphingobium sp. tcm1 155000.0 1 PMID:31832710 -3.1.3.1 * sphingomonas sp. bsar-1 200000.0 2 PMID:18641147;PMID:718947 -3.1.3.1 * synechococcus elongatus pcc 7942 = fachb-805 160000.0 1 PMID:16666051 -3.1.3.1 * thermotoga maritima 45000.0 1 PMID:11910033 -3.1.3.1 * thermotoga neapolitana 87000.0 4 PMID:11265472;PMID:9322373 -3.1.3.1 * thermus sp. 54407.0 2 * -3.1.3.1 * thermus sp. ntu-237 109000.0 1 * -3.1.3.1 * thermus thermophilus 54700.0 1 PMID:17989875 -3.1.3.1 * thermus yunnanensis 104000.0 2 PMID:15955749 -3.1.3.1 * ulva pertusa 19500.0 1 PMID:12784882 -3.1.3.1 * vibrio sp. 55000.0 2 PMID:10862903;PMID:15906116 -3.1.3.1 * walterinnesia aegyptia 80000.0 2 PMID:12503880 -3.1.3.10 * bombyx mori 102000.0 8 * -3.1.3.10 * citrobacter braakii 46000.0 2 PMID:19940380 -3.1.3.10 * enterobacter cloacae 125000.0 4 PMID:16193276 -3.1.3.10 * escherichia coli 45680.0 2 PMID:11173491;PMID:2844729 -3.1.3.10 * pholiota microspora 35000.0 1 PMID:9972248 -3.1.3.100 * gallus gallus 17800.0 2 PMID:25816604 -3.1.3.100 * saccharomyces cerevisiae 56000.0 1 PMID:3048416 -3.1.3.100 * zea mays 24000.0 1 PMID:19167902 -3.1.3.102 * arabidopsis thaliana 43600.0 3 PMID:16183635 -3.1.3.102 * pisum sativum cv. bohatyr 59400.0 1 PMID:22002057 -3.1.3.104 * arabidopsis thaliana 72100.0 4 PMID:27490826 -3.1.3.104 * bacillus subtilis 32000.0 2 PMID:26316208;PMID:32040605 -3.1.3.106 * arachis hypogaea 39000.0 1 PMID:11891254 -3.1.3.11 * bacillus licheniformis 500000.0 1 PMID:6296615 -3.1.3.11 * bacillus methanolicus 142000.0 4 PMID:24013630 -3.1.3.11 * bacillus subtilis 380000.0 2 PMID:221467 -3.1.3.11 * bombus terrestris 142000.0 1 PMID:6296612 -3.1.3.11 * bos taurus 143000.0 5 PMID:12904832;PMID:237195;PMID:239683;PMID:4335478;PMID:6296605 -3.1.3.11 * canis lupus familiaris 147000.0 1 * -3.1.3.11 * corynebacterium glutamicum 140000.0 2 PMID:12904832;PMID:239683;PMID:6296605 -3.1.3.11 * cyberlindnera jadinii 130000.0 2 PMID:237192;PMID:4342108;PMID:6086609;PMID:6296609;PMID:6296614 -3.1.3.11 * escherichia coli 150000.0 8 PMID:10986273;PMID:11825604;PMID:1322844;PMID:15295071;PMID:19073594;PMID:6312898 -3.1.3.11 * euglena gracilis 210000.0 5 PMID:25906744;PMID:26214137 -3.1.3.11 * gallus gallus 144000.0 3 PMID:20849;PMID:237193;PMID:4364115;PMID:6250626;PMID:6296606;PMID:6296607 -3.1.3.11 * homo sapiens 144000.0 2 PMID:20849;PMID:237193;PMID:4364115;PMID:6250626;PMID:6296606;PMID:6296607 -3.1.3.11 * kluyveromyces marxianus 155000.0 2 PMID:237192;PMID:6086609;PMID:6296609 -3.1.3.11 * lathyrus oleraceus 150000.0 6 PMID:11825604;PMID:12651105;PMID:1322844;PMID:15295071;PMID:6249201;PMID:6296611;PMID:6312898 -3.1.3.11 * malus domestica 150000.0 2 PMID:11825604;PMID:15295071;PMID:6249201;PMID:6296611 -3.1.3.11 * meleagris gallopavo 144000.0 3 PMID:198399;PMID:20849;PMID:237193;PMID:4364115;PMID:6250626;PMID:6296606;PMID:6296607 -3.1.3.11 * mus musculus 146000.0 6 PMID:19400047;PMID:212415;PMID:2537640;PMID:40966;PMID:4335956;PMID:6296609;PMID:6296611 -3.1.3.11 * mycobacterium tuberculosis 127000.0 3 PMID:21451980;PMID:21636919 -3.1.3.11 * mytilus galloprovincialis 105000.0 2 PMID:20849;PMID:237193;PMID:4364115;PMID:6250626;PMID:6296606;PMID:6296607 -3.1.3.11 * oryctolagus cuniculus 145000.0 8 PMID:15295071;PMID:20849;PMID:237193;PMID:4335956;PMID:4364115;PMID:6249201;PMID:6250626;PMID:6296606;PMID:6296607;PMID:6296608;PMID:6296611 -3.1.3.11 * oryza coarctata 170000.0 2 PMID:11337074 -3.1.3.11 * oryza sativa 170000.0 2 PMID:11337074 -3.1.3.11 * ovis aries 146300.0 3 PMID:6277165;PMID:6316885 -3.1.3.11 * pelophylax lessonae 37300.0 2 PMID:10327613;PMID:20656052;PMID:8387281 -3.1.3.11 * phocidae 147000.0 2 PMID:6277165 -3.1.3.11 * ptyas dhumnades 140000.0 3 PMID:10987362;PMID:19400047;PMID:212415;PMID:237192;PMID:6086609;PMID:6296609;PMID:6296611 -3.1.3.11 * pyrobaculum calidifontis 44513.0 1 PMID:28299451 -3.1.3.11 * pyrococcus furiosus 66800.0 3 PMID:12029059 -3.1.3.11 * rattus norvegicus 143000.0 10 PMID:20849;PMID:237193;PMID:26417114;PMID:2994743;PMID:3017926;PMID:4364115;PMID:6250626;PMID:6296606;PMID:6296607;PMID:6296610 -3.1.3.11 * rhodococcus opacus 190000.0 2 * -3.1.3.11 * rhodopseudomonas palustris 130000.0 1 PMID:237192;PMID:4342108;PMID:6296614 -3.1.3.11 * saccharomyces cerevisiae 116000.0 4 PMID:232395;PMID:2834361;PMID:6327710 -3.1.3.11 * schizosaccharomyces pombe 38380.0 1 PMID:2834361 -3.1.3.11 * spinacia oleracea 195000.0 8 PMID:19400047;PMID:210163;PMID:212415;PMID:6296609;PMID:6296611;PMID:6296613 -3.1.3.11 * sus scrofa 146100.0 6 PMID:11825604;PMID:20656052;PMID:6277165;PMID:6296821;PMID:8387281 -3.1.3.11 * synechococcus sp. 168000.0 6 PMID:8837735;PMID:9602137 -3.1.3.11 * thermococcus kodakarensis 340000.0 2 PMID:12065581 -3.1.3.11 * thermotoga maritima 28000.0 1 * -3.1.3.11 * thermus thermophilus 80000.0 3 PMID:20600937 -3.1.3.11 * triticum aestivum 38900.0 1 PMID:10910732 -3.1.3.11 * zea mays 184000.0 2 PMID:6263905 -3.1.3.12 * arthrobacter sp. 28000.0 2 PMID:22806197 -3.1.3.12 * aspergillus nidulans 26360.0 1 PMID:8809779 -3.1.3.12 * brugia malayi 60000.0 1 PMID:21658361 -3.1.3.12 * burkholderia pseudomallei 32000.0 1 PMID:31973820 -3.1.3.12 * cyberlindnera jadinii 82108.0 2 PMID:24446217 -3.1.3.12 * escherichia coli 973000.0 4 PMID:10831428;PMID:11004189;PMID:11895938;PMID:12586876;PMID:20217281 -3.1.3.12 * mycobacterium tuberculosis 46236.0 4 PMID:15158675;PMID:17266712;PMID:23903290 -3.1.3.12 * mycobacterium tuberculosis variant bovis 42000.0 1 PMID:17266712 -3.1.3.12 * mycolicibacterium smegmatis 27000.0 1 PMID:12417583 -3.1.3.12 * oryza sativa japonica group 45000.0 2 PMID:17257172 -3.1.3.12 * phormia regina 26000.0 1 PMID:4326209 -3.1.3.12 * rhizophagus intraradices 89700.0 1 PMID:17504469 -3.1.3.12 * rubrobacter xylanophilus 29400.0 1 PMID:18835983 -3.1.3.12 * saccharomyces cerevisiae 973000.0 1 PMID:11004189;PMID:11895938;PMID:12586876 -3.1.3.12 * schizosaccharomyces pombe 973000.0 1 PMID:11004189;PMID:11895938;PMID:12586876 -3.1.3.12 * thermoproteus tenax 81000.0 3 PMID:23626675 -3.1.3.12 * zygosaccharomyces rouxii 104000.0 1 PMID:12748054 -3.1.3.15 * buchnera aphidicola 41300.0 1 PMID:9767718 -3.1.3.15 * escherichia coli 19903.0 1 PMID:16966333 -3.1.3.15 * medicago truncatula 61358.0 1 PMID:26994138 -3.1.3.15 * mycobacterium tuberculosis 56000.0 1 PMID:29752410 -3.1.3.15 * saccharomyces cerevisiae 38000.0 1 PMID:4351203 -3.1.3.15 * salmonella enterica subsp. enterica serovar typhimurium 75000.0 3 PMID:4349042;PMID:4366369;PMID:4371845;PMID:6246956 -3.1.3.15 * thermococcus onnurineus 39000.0 1 PMID:18223080 -3.1.3.15 * thermus thermophilus 119900.0 6 PMID:14993698;PMID:17929834 -3.1.3.16 * arabidopsis thaliana 115000.0 4 PMID:11716463;PMID:11738087 -3.1.3.16 * artemia sp. 346000.0 2 * -3.1.3.16 * bos taurus 140000.0 7 PMID:1848859;PMID:19629647;PMID:3037526;PMID:4351138 -3.1.3.16 * busycotypus canaliculatus 82000.0 2 PMID:8739044 -3.1.3.16 * canis lupus familiaris 61000.0 2 PMID:206432 -3.1.3.16 * cavia porcellus 260000.0 1 PMID:3040407;PMID:6254774 -3.1.3.16 * dictyostelium discoideum 65000.0 3 PMID:10452519 -3.1.3.16 * drosophila melanogaster 37000.0 2 PMID:11747299;PMID:18256265 -3.1.3.16 * gallus gallus 109000.0 1 PMID:2985450 -3.1.3.16 * glycine max 32000.0 1 PMID:16661438;PMID:191081 -3.1.3.16 * homo sapiens 600000.0 39 PMID:11495355;PMID:1328247;PMID:15383005;PMID:16685424;PMID:17269486;PMID:18186651;PMID:18256265;PMID:18334487;PMID:18424272;PMID:18566123;PMID:18922469;PMID:18925649;PMID:22284538;PMID:22639363;PMID:23269362;PMID:25012655;PMID:2831201;PMID:9276686;PMID:9430683;PMID:9521129 -3.1.3.16 * lambdavirus lambda 25000.0 1 PMID:8394350 -3.1.3.16 * mammalia 90000.0 1 * -3.1.3.16 * meleagris gallopavo 230000.0 2 * -3.1.3.16 * methanosarcina thermophila 30800.0 1 PMID:9260948 -3.1.3.16 * mus musculus 67000.0 5 PMID:17029793;PMID:18299321;PMID:18641122;PMID:23782844 -3.1.3.16 * mycoplasmopsis synoviae 30087.0 1 PMID:25370051 -3.1.3.16 * neurospora crassa 35000.0 2 PMID:8529028 -3.1.3.16 * oryctolagus cuniculus 260000.0 8 PMID:2823547;PMID:2985385 -3.1.3.16 * plasmodium falciparum 80000.0 2 PMID:11377737;PMID:11897131 -3.1.3.16 * pseudomonas aeruginosa 27000.0 1 PMID:10542161 -3.1.3.16 * psophocarpus tetragonolobus 92000.0 2 PMID:10513400 -3.1.3.16 * pyricularia oryzae 36000.0 1 PMID:22639363;PMID:23269362 -3.1.3.16 * pyrodictium abyssi 33340.0 1 PMID:9696747 -3.1.3.16 * rattus norvegicus 260000.0 22 PMID:12963337;PMID:15376558;PMID:16661438;PMID:17562162;PMID:18543252;PMID:191081;PMID:19717566;PMID:3040407;PMID:6244946;PMID:6254774;PMID:7514397;PMID:7592845;PMID:8660676 -3.1.3.16 * saccharolobus solfataricus 33765.0 2 PMID:7592428;PMID:8384214 -3.1.3.16 * saccharomyces cerevisiae 60000.0 3 PMID:12135475;PMID:16442612;PMID:16690953 -3.1.3.16 * salmonella enterica 51000.0 2 PMID:15817783 -3.1.3.16 * solanum lycopersicum 63000.0 2 PMID:12972652 -3.1.3.16 * sus scrofa 224000.0 7 PMID:6296103 -3.1.3.16 * triticum aestivum 180000.0 2 PMID:2840890 -3.1.3.16 * trypanosoma brucei 53000.0 2 PMID:11290414;PMID:17304789 -3.1.3.16 * tulipa gesneriana 75000.0 3 PMID:17129401 -3.1.3.16 * xenopus laevis 130000.0 2 PMID:12605688 -3.1.3.16 * zea mays 200000.0 11 PMID:11004556;PMID:11506360 -3.1.3.17 * bos taurus 260000.0 3 PMID:205466;PMID:217307;PMID:2992391 -3.1.3.17 * homo sapiens 250000.0 1 PMID:36239169 -3.1.3.17 * oryctolagus cuniculus 38000.0 8 PMID:1730696;PMID:205466;PMID:20939;PMID:240850;PMID:2842603;PMID:3010875 -3.1.3.17 * rattus norvegicus 160000.0 1 PMID:2157500 -3.1.3.17 * saccharomyces cerevisiae 78000.0 1 PMID:6299361 -3.1.3.18 * chlamydomonas reinhardtii 92000.0 3 PMID:11581250;PMID:16664420 -3.1.3.18 * escherichia coli 27390.0 1 PMID:13129953 -3.1.3.18 * homo sapiens 79000.0 3 PMID:14966;PMID:6258579 -3.1.3.18 * lathyrus oleraceus 100000.0 2 * -3.1.3.18 * nicotiana tabacum 93000.0 4 PMID:204630 -3.1.3.18 * oryza sativa japonica group 65000.0 1 PMID:35083835 -3.1.3.18 * plasmodium berghei 78000.0 2 PMID:30700551 -3.1.3.18 * shigella flexneri 27000.0 1 PMID:19153451 -3.1.3.18 * zea mays 61500.0 2 PMID:24232028 -3.1.3.2 * acidithiobacillus thiooxidans 130000.0 1 PMID:4609973 -3.1.3.2 * agaricus bisporus 145000.0 2 PMID:15188886 -3.1.3.2 * arabidopsis thaliana 250000.0 14 PMID:16963519;PMID:18065557;PMID:1897950;PMID:19633233;PMID:20545876;PMID:21941000;PMID:23745690;PMID:5776528;PMID:7287728 -3.1.3.2 * arachis hypogaea 120000.0 8 PMID:12913313;PMID:7549937 -3.1.3.2 * asclepias curassavica 27000.0 1 PMID:7283439 -3.1.3.2 * aspergillus caespitosus 190000.0 4 PMID:14871174 -3.1.3.2 * aspergillus ficuum 65500.0 1 PMID:20144543 -3.1.3.2 * aspergillus nidulans 100000.0 1 PMID:10446377;PMID:18451497;PMID:4552990 -3.1.3.2 * aspergillus niger 310000.0 2 PMID:13843 -3.1.3.2 * aspergillus phoenicis 122000.0 1 * -3.1.3.2 * beta vulgaris 82000.0 1 PMID:15153189 -3.1.3.2 * blastobotrys adeninivorans 350000.0 4 PMID:17016743 -3.1.3.2 * bos taurus 42000.0 7 PMID:3027088;PMID:4750764;PMID:4975223;PMID:6282821;PMID:7212711;PMID:952892 -3.1.3.2 * brassica nigra 60000.0 2 PMID:1897950;PMID:19633233 -3.1.3.2 * candida albicans 124300.0 2 PMID:4633344 -3.1.3.2 * carthamus oxyacanthus 36000.0 1 PMID:36481331 -3.1.3.2 * clostridium perfringens 32500.0 2 PMID:19363079;PMID:19833778 -3.1.3.2 * corylus avellana 81500.0 1 PMID:15048567 -3.1.3.2 * cryptosporidium parvum 31000.0 2 PMID:17252269;PMID:17415667 -3.1.3.2 * cullen corylifolium 30000.0 2 * -3.1.3.2 * cutibacterium acnes 93000.0 1 PMID:33598;PMID:7420057 -3.1.3.2 * dioscorea cayenensis-rotundata 98000.0 5 * -3.1.3.2 * drosophila melanogaster 90000.0 2 PMID:6090300;PMID:6776114 -3.1.3.2 * eimeria tenella 44000.0 1 PMID:3371447 -3.1.3.2 * eisenia veneta 113000.0 2 PMID:11026660 -3.1.3.2 * entamoeba histolytica 97000.0 1 PMID:10779571 -3.1.3.2 * escherichia coli 45000.0 2 PMID:4750764;PMID:6282821 -3.1.3.2 * euphorbia characias 130000.0 2 PMID:21639850 -3.1.3.2 * francisella tularensis 136000.0 4 PMID:15964202;PMID:8631917 -3.1.3.2 * gallus gallus 102000.0 2 PMID:7287728;PMID:9226888 -3.1.3.2 * glycine max 53000.0 2 PMID:15278453;PMID:2829734 -3.1.3.2 * gossypium hirsutum 200000.0 2 * -3.1.3.2 * haemophilus influenzae 28510.0 2 PMID:16682777;PMID:17824671 -3.1.3.2 * helianthus annuus 103000.0 3 * -3.1.3.2 * helicobacter pylori 72000.0 3 PMID:21617345 -3.1.3.2 * heterostelium pallidum 160000.0 2 PMID:4856509 -3.1.3.2 * homo sapiens 120000.0 18 PMID:10446377;PMID:15280042;PMID:18451497;PMID:2268668;PMID:2775236;PMID:33598;PMID:3988771;PMID:4552990;PMID:6090300;PMID:6404297;PMID:6776114;PMID:7420057;PMID:8288593 -3.1.3.2 * hordeum vulgare 79000.0 3 PMID:17023171;PMID:2294973 -3.1.3.2 * hypericum perforatum 57000.0 2 * -3.1.3.2 * ipomoea batatas 400000.0 9 PMID:12913313;PMID:15631514;PMID:16623702;PMID:16963519;PMID:7287728;PMID:7549937;PMID:9226888 -3.1.3.2 * labeo rohita 100000.0 3 PMID:10446377;PMID:18451497;PMID:4552990 -3.1.3.2 * lactiplantibacillus pentosus 69000.0 1 PMID:15610436;PMID:2753875 -3.1.3.2 * landoltia punctata 120000.0 2 PMID:12913313;PMID:15631514 -3.1.3.2 * latilactobacillus curvatus 104000.0 2 * -3.1.3.2 * legionella micdadei 146000.0 3 PMID:2998281 -3.1.3.2 * leishmania mexicana 72000.0 2 PMID:1857378 -3.1.3.2 * lens culinaris 100000.0 2 PMID:10446377;PMID:18451497;PMID:4552990 -3.1.3.2 * lupinus luteus 93500.0 4 PMID:9300805 -3.1.3.2 * macrotyloma uniflorum 55000.0 1 PMID:29358824 -3.1.3.2 * moraxella catarrhalis 103000.0 1 PMID:18065547 -3.1.3.2 * mucor hiemalis 45000.0 2 PMID:17889394 -3.1.3.2 * mus musculus 45000.0 1 PMID:19158948 -3.1.3.2 * musa cavendishii 41000.0 2 PMID:11800388 -3.1.3.2 * nelumbo nucifera 80000.0 1 PMID:25887488 -3.1.3.2 * neurospora crassa 85000.0 2 PMID:5545084 -3.1.3.2 * nicotiana tabacum 220000.0 7 PMID:18762304;PMID:1909579;PMID:22698754 -3.1.3.2 * opuntia megacantha 44000.0 1 PMID:32454111 -3.1.3.2 * oryctolagus cuniculus 123000.0 6 PMID:4748362;PMID:736900 -3.1.3.2 * oryza sativa 69000.0 2 PMID:17252269;PMID:17415667;PMID:19838636 -3.1.3.2 * paracoccus denitrificans 67000.0 1 PMID:16531056;PMID:197075 -3.1.3.2 * pelophylax lessonae 35615.0 2 PMID:1612187 -3.1.3.2 * penicillium chrysogenum 57000.0 2 PMID:1909579;PMID:22698754 -3.1.3.2 * phaseolus vulgaris 123000.0 16 PMID:15247223;PMID:15331086;PMID:17258469;PMID:19955264 -3.1.3.2 * pinctada fucata 208800.0 4 PMID:16380281;PMID:17619219 -3.1.3.2 * pinus sylvestris 68000.0 1 PMID:7284400 -3.1.3.2 * pteromalus puparum 45900.0 1 PMID:18448143 -3.1.3.2 * rattus norvegicus 320000.0 15 PMID:11685369;PMID:2732218;PMID:3085593;PMID:3235452;PMID:5723453;PMID:6706919;PMID:8063012;PMID:8430088 -3.1.3.2 * rumex dentatus 96000.0 1 PMID:15247223 -3.1.3.2 * saccharomyces cerevisiae 252000.0 2 PMID:2407294;PMID:6363410 -3.1.3.2 * salmonella enterica subsp. enterica serovar typhimurium 24000.0 1 PMID:3049613 -3.1.3.2 * schizophyllum commune 72500.0 1 PMID:23322529 -3.1.3.2 * schizosaccharomyces pombe 383000.0 5 PMID:238577;PMID:7217063 -3.1.3.2 * sinorhizobium meliloti 70000.0 3 PMID:11685369;PMID:8063012;PMID:9639599 -3.1.3.2 * solanum lycopersicum 142000.0 15 PMID:11024303;PMID:14521509;PMID:16665451;PMID:17080645 -3.1.3.2 * solanum tuberosum 72000.0 4 PMID:16531056;PMID:197075 -3.1.3.2 * sorghum bicolor 27000.0 2 PMID:7283439 -3.1.3.2 * sphingobium sp. rsms 55000.0 1 PMID:35242619 -3.1.3.2 * staphylococcus aureus 58000.0 1 PMID:19633233;PMID:23745690;PMID:5776528 -3.1.3.2 * streptococcus equi 32000.0 1 PMID:11108009 -3.1.3.2 * sulfolobus acidocaldarius 25000.0 3 PMID:10568805 -3.1.3.2 * sus scrofa 67000.0 1 PMID:15519293 -3.1.3.2 * talaromyces funiculosus 69000.0 3 PMID:15610436;PMID:2753875 -3.1.3.2 * tetradesmus obliquus 56100.0 1 * -3.1.3.2 * tetrahymena pyriformis 120000.0 2 PMID:12913313;PMID:7549937 -3.1.3.2 * thermus thermophilus 28400.0 1 PMID:20378986 -3.1.3.2 * trichoderma harzianum 326000.0 2 PMID:20364293;PMID:26938873 -3.1.3.2 * triticum aestivum 60000.0 3 PMID:1898053 -3.1.3.2 * trypanosoma brucei 70000.0 1 PMID:2226816 -3.1.3.2 * trypanosoma brucei brucei 45000.0 3 PMID:19442761 -3.1.3.2 * ustilago esculenta 343000.0 2 * -3.1.3.2 * vigna aconitifolia 58000.0 3 PMID:19633233;PMID:23745690;PMID:5776528 -3.1.3.2 * vigna mungo 25000.0 1 PMID:10568805 -3.1.3.2 * xenopus laevis 200000.0 4 * -3.1.3.2 * zea mays 76000.0 3 PMID:17023171;PMID:2294973 -3.1.3.2 * zymomonas mobilis 28988.0 1 PMID:2914872 -3.1.3.20 * veillonella parvula 50000.0 1 PMID:6271379 -3.1.3.21 * arabidopsis thaliana 33000.0 2 PMID:17136424 -3.1.3.21 * corynebacterium glutamicum 58600.0 1 PMID:22353596 -3.1.3.21 * dunaliella salina 86000.0 1 * -3.1.3.21 * mycobacterium tuberculosis 37904.0 1 PMID:24359335 -3.1.3.21 * saccharomyces cerevisiae 30400.0 3 PMID:18558342;PMID:8662716 -3.1.3.22 * caloglossa continua 30200.0 2 PMID:14961343 -3.1.3.22 * ectocarpus siliculosus 155000.0 2 PMID:24323504 -3.1.3.22 * eimeria tenella 34740.0 2 PMID:9461622 -3.1.3.23 * arabidopsis thaliana 42700.0 1 PMID:24915748 -3.1.3.23 * bacillus subtilis 28900.0 1 PMID:21575135 -3.1.3.23 * escherichia acidilactici 99000.0 1 PMID:6322944 -3.1.3.23 * escherichia coli 101000.0 6 PMID:6322944 -3.1.3.23 * klebsiella aerogenes 98000.0 1 PMID:6322944 -3.1.3.23 * neisseria meningitidis 100000.0 2 PMID:6322944 -3.1.3.23 * plasmodium falciparum 33000.0 1 PMID:25058848 -3.1.3.23 * saccharomyces cerevisiae 100000.0 1 PMID:6322944 -3.1.3.24 * anabaena sp. 32000.0 4 PMID:11800389 -3.1.3.24 * arabidopsis thaliana 90000.0 2 PMID:27855180 -3.1.3.24 * coffea arabica 46700.0 1 PMID:18384509 -3.1.3.24 * coffea canephora 46700.0 1 PMID:18384509 -3.1.3.24 * lathyrus oleraceus 115000.0 2 * -3.1.3.24 * methylobacillus flagellatus 336000.0 2 PMID:23865613 -3.1.3.24 * oryza sativa 120000.0 3 PMID:11050182 -3.1.3.24 * zea mays 47213.0 1 PMID:11050182 -3.1.3.25 * anguilla anguilla 31000.0 1 PMID:20547660 -3.1.3.25 * archaeoglobus fulgidus 28000.0 2 PMID:12649434;PMID:17616624 -3.1.3.25 * bos taurus 59000.0 4 PMID:11882005;PMID:1319157;PMID:2845918;PMID:3600356;PMID:6253491;PMID:8152337;PMID:8391785 -3.1.3.25 * escherichia coli 39000.0 4 PMID:10747806;PMID:10844654 -3.1.3.25 * gallus gallus 60000.0 1 PMID:6272635 -3.1.3.25 * glycine max 29000.0 1 PMID:11911470;PMID:17241743 -3.1.3.25 * homo sapiens 64900.0 4 PMID:1377913;PMID:17305585;PMID:21213002 -3.1.3.25 * hordeum vulgare 37000.0 1 PMID:18493722 -3.1.3.25 * lilium longiflorum 54000.0 2 PMID:16662572;PMID:16663819;PMID:2999094;PMID:8391785 -3.1.3.25 * methanocaldococcus jannaschii 55000.0 3 PMID:17616624;PMID:2999094;PMID:9647837 -3.1.3.25 * mus musculus 70000.0 2 PMID:17068342 -3.1.3.25 * mycobacterium tuberculosis 93000.0 8 PMID:11914086;PMID:16325768;PMID:17725819 -3.1.3.25 * rattus norvegicus 210000.0 9 PMID:1319157;PMID:16663819;PMID:2845918;PMID:2999094;PMID:3600356;PMID:4372945;PMID:6253491;PMID:8152337;PMID:8391785;PMID:9647837 -3.1.3.25 * rhizobium leguminosarum 30350.0 1 PMID:11285742 -3.1.3.25 * saccharomyces cerevisiae 32000.0 2 PMID:10747806;PMID:10844654 -3.1.3.25 * sus scrofa 67000.0 3 PMID:11911470;PMID:17241743 -3.1.3.25 * synechocystis sp. 32000.0 1 PMID:17123102 -3.1.3.25 * thermotoga maritima 119000.0 4 PMID:10508089 -3.1.3.26 * agrocybe pediades 59000.0 1 PMID:11571175 -3.1.3.26 * aspergillus ficuum 100000.0 1 PMID:10964658 -3.1.3.26 * aspergillus fumigatus 100000.0 4 PMID:10679211;PMID:10964658;PMID:16787007;PMID:19120634 -3.1.3.26 * aspergillus japonicus 66000.0 1 PMID:19025560 -3.1.3.26 * aspergillus niger 183000.0 9 PMID:12653285;PMID:12693443;PMID:15776271;PMID:17450356;PMID:18683944;PMID:19025560 -3.1.3.26 * aspergillus terreus 214000.0 1 PMID:12693443 -3.1.3.26 * avena sativa 68000.0 2 * -3.1.3.26 * bacillus licheniformis 47000.0 1 PMID:12111145;PMID:14514072 -3.1.3.26 * bacillus sp. (in: firmicutes) 46000.0 4 PMID:11594462;PMID:12693443;PMID:18479345 -3.1.3.26 * bacillus subtilis 44000.0 5 PMID:12111145;PMID:12693443;PMID:18543132;PMID:18785018 -3.1.3.26 * brassica napus 71000.0 1 PMID:12226456 -3.1.3.26 * brevundimonas sp. gc-2-c 37500.0 1 PMID:19151187 -3.1.3.26 * burkholderia sp. a13(2014) 44000.0 1 PMID:25833676 -3.1.3.26 * ceriporia sp. 59000.0 2 PMID:11571175 -3.1.3.26 * citrobacter amalonaticus 49000.0 2 PMID:17657539 -3.1.3.26 * citrobacter braakii 47000.0 1 PMID:12111145;PMID:14514072 -3.1.3.26 * corylus avellana 72000.0 2 PMID:13679091 -3.1.3.26 * cucurbita maxima 66500.0 2 * -3.1.3.26 * cyberlindnera fabianii 75000.0 2 PMID:19664557 -3.1.3.26 * debaryomyces castellii 53000.0 2 PMID:18242101 -3.1.3.26 * enterobacter sp. acss 62000.0 1 PMID:27250653 -3.1.3.26 * escherichia coli 43000.0 2 PMID:8387749 -3.1.3.26 * glycine max 130000.0 2 PMID:11500558;PMID:2829733 -3.1.3.26 * klebsiella aerogenes 700000.0 1 PMID:12693443 -3.1.3.26 * lilium longiflorum 88000.0 1 PMID:16665018 -3.1.3.26 * lupinus albus 65000.0 4 PMID:12405788 -3.1.3.26 * oryza sativa japonica group 66000.0 1 PMID:21220762 -3.1.3.26 * pectobacterium wasabiae 48000.0 2 PMID:17034758;PMID:18667849 -3.1.3.26 * penicillium caseoicolum 81000.0 1 PMID:12693443 -3.1.3.26 * penicillium simplicissimum 65000.0 1 PMID:11271818 -3.1.3.26 * peniophora lycii 118400.0 4 PMID:11571175;PMID:12659840;PMID:16605274 -3.1.3.26 * pseudomonas syringae 45000.0 1 PMID:14629009 -3.1.3.26 * rattus norvegicus 90000.0 2 PMID:1654110 -3.1.3.26 * rhizopus microsporus var. oligosporus 124000.0 2 PMID:15163521 -3.1.3.26 * schwanniomyces castellii 490000.0 1 PMID:12693443 -3.1.3.26 * schwanniomyces occidentalis 490000.0 1 PMID:12693443 -3.1.3.26 * secale cereale 67000.0 2 * -3.1.3.26 * selenomonas ruminantium 46000.0 1 PMID:12693443 -3.1.3.26 * thermothelomyces heterothallicus 456000.0 2 PMID:16787007;PMID:19120634 -3.1.3.26 * trametes pubescens 62000.0 1 PMID:11571175 -3.1.3.26 * uncultured bacterium 42000.0 1 PMID:25588560 -3.1.3.26 * vigna radiata var. radiata 158000.0 1 * -3.1.3.26 * wickerhamomyces anomalus 64000.0 1 PMID:12693443 -3.1.3.26 * yersinia intermedia 45000.0 1 PMID:17034758;PMID:18667849 -3.1.3.26 * yersinia pestis 45200.0 1 PMID:18548246 -3.1.3.26 * yersinia rohdei 46100.0 1 PMID:18548246 -3.1.3.26 * zea mays 76000.0 3 PMID:12226456;PMID:8240238 -3.1.3.27 * escherichia coli 29000.0 1 PMID:24821770 -3.1.3.3 * arabidopsis thaliana 37000.0 1 PMID:10196182 -3.1.3.3 * bos taurus 65000.0 1 PMID:4374244 -3.1.3.3 * escherichia coli 38000.0 1 PMID:6318053 -3.1.3.3 * hydrogenobacter thermophilus 46000.0 5 PMID:22337887 -3.1.3.3 * mus musculus 47000.0 1 PMID:4309589 -3.1.3.3 * mycobacterium tuberculosis 45000.0 1 PMID:25037224 -3.1.3.3 * rattus norvegicus 25000.0 1 PMID:19747453 -3.1.3.3 * thermus thermophilus 52100.0 2 PMID:30430741 -3.1.3.32 * arabidopsis thaliana 73000.0 1 PMID:11948185 -3.1.3.32 * bos taurus 60000.0 1 PMID:10227382 -3.1.3.32 * homo sapiens 57100.0 2 PMID:10446192;PMID:19773431 -3.1.3.32 * omegavirus omega 160000.0 2 PMID:15056675 -3.1.3.32 * plasmodium falciparum 55584.0 1 PMID:21821066 -3.1.3.32 * rattus norvegicus 79000.0 2 PMID:2828058 -3.1.3.32 * schizosaccharomyces pombe 45000.0 1 PMID:12056900 -3.1.3.35 * bacillus subtilis 40000.0 1 PMID:99634 -3.1.3.36 * bos taurus 115000.0 1 PMID:7508913 -3.1.3.36 * crithidia fasciculata 120000.0 2 PMID:6271362 -3.1.3.36 * homo sapiens 170000.0 4 PMID:17158794;PMID:23443536;PMID:6271223 -3.1.3.36 * mus musculus 72000.0 1 PMID:10806194 -3.1.3.36 * rhodnius prolixus 36500.0 1 PMID:16634626 -3.1.3.37 * bacillus methanolicus 132000.0 2 PMID:24013630 -3.1.3.37 * chlamydomonas sp. w80 41600.0 1 PMID:15849430 -3.1.3.37 * cucumis sativus 42000.0 1 * -3.1.3.37 * cyberlindnera jadinii 75000.0 2 PMID:237192;PMID:3032163;PMID:4329855 -3.1.3.37 * spinacia oleracea 66000.0 4 PMID:237192;PMID:3032163;PMID:4329855 -3.1.3.37 * synechococcus sp. 40000.0 1 PMID:18222961 -3.1.3.37 * synechocystis sp. 48000.0 1 PMID:22244776 -3.1.3.37 * triticum aestivum 56000.0 1 PMID:6296616 -3.1.3.37 * zea mays 38000.0 1 PMID:6263905 -3.1.3.38 * saccharum sp. 160000.0 2 PMID:10970181 -3.1.3.4 * acholeplasma laidlawii 25000.0 1 PMID:9408176 -3.1.3.4 * arabidopsis thaliana 101000.0 6 PMID:17652095;PMID:19923426 -3.1.3.4 * cavia porcellus 35000.0 3 PMID:18215144 -3.1.3.4 * cricetulus griseus 34000.0 3 PMID:18215144 -3.1.3.4 * eimeria tenella 120000.0 8 PMID:25861032 -3.1.3.4 * homo sapiens 60000.0 10 PMID:16467304;PMID:17200142;PMID:18215144;PMID:18930839;PMID:9305923 -3.1.3.4 * mus musculus 140000.0 3 PMID:17105729;PMID:18362392 -3.1.3.4 * rattus norvegicus 300000.0 5 PMID:15271294;PMID:7642624;PMID:8948459 -3.1.3.4 * saccharomyces cerevisiae 124000.0 7 PMID:18812320;PMID:6091767;PMID:9370315 -3.1.3.4 * streptomyces coelicolor 40000.0 2 PMID:23356794 -3.1.3.4 * sus scrofa 218000.0 2 PMID:1334090 -3.1.3.4 * vigna radiata 37000.0 1 PMID:8869881 -3.1.3.42 * oryctolagus cuniculus 49000.0 2 PMID:223553 -3.1.3.42 * rattus norvegicus 50000.0 3 PMID:2842608;PMID:6250627;PMID:6273162 -3.1.3.42 * saccharomyces cerevisiae 160000.0 4 PMID:1645716 -3.1.3.43 * ascaris suum 150000.0 1 PMID:1664050 -3.1.3.43 * bos taurus 150000.0 15 PMID:10410249;PMID:11035961;PMID:4401694;PMID:6288374;PMID:6293549;PMID:6296618;PMID:8396421;PMID:9395502 -3.1.3.43 * mammalia 69000.0 2 PMID:12631265 -3.1.3.43 * mus musculus 80000.0 1 PMID:9013878 -3.1.3.43 * rattus norvegicus 96000.0 2 PMID:17532339 -3.1.3.43 * sus scrofa 95000.0 1 PMID:4339646 -3.1.3.44 * rattus norvegicus 250000.0 2 PMID:6111317;PMID:6257718 -3.1.3.45 * burkholderia pseudomallei 90000.0 1 * -3.1.3.45 * escherichia coli 89000.0 4 PMID:12639950;PMID:6246070 -3.1.3.46 * arabidopsis thaliana 370000.0 4 PMID:11672433;PMID:11673618 -3.1.3.46 * bos taurus 100000.0 2 PMID:1659398 -3.1.3.46 * gallus gallus 100000.0 2 PMID:3019688;PMID:6100582 -3.1.3.46 * homo sapiens 58000.0 3 PMID:24280138;PMID:9276680 -3.1.3.46 * pigeon 100000.0 2 PMID:3019688;PMID:6100582 -3.1.3.46 * rattus norvegicus 110000.0 7 PMID:1339450;PMID:22668829;PMID:3014526;PMID:3019688;PMID:6100582;PMID:8391552 -3.1.3.46 * saccharomyces cerevisiae 110000.0 2 PMID:2831055 -3.1.3.46 * spinacia oleracea 320000.0 4 PMID:11856361;PMID:2538421 -3.1.3.46 * trypanosoma brucei 600000.0 3 PMID:16008555 -3.1.3.47 * rattus norvegicus 480000.0 7 PMID:6260210;PMID:6330255;PMID:6631216;PMID:6830840 -3.1.3.48 * bos taurus 52000.0 3 PMID:15543943;PMID:3034101 -3.1.3.48 * cotesia vestalis bracovirus 59000.0 2 PMID:18425572 -3.1.3.48 * drosophila melanogaster 62100.0 2 PMID:18281928 -3.1.3.48 * entamoeba histolytica 28000.0 1 PMID:26431820 -3.1.3.48 * francisella tularensis 37200.0 1 PMID:16511256 -3.1.3.48 * gallus gallus 180000.0 3 PMID:17178832;PMID:6199163 -3.1.3.48 * homo sapiens 185000.0 24 PMID:12112018;PMID:12745253;PMID:15070900;PMID:17005559;PMID:17224080;PMID:18078820;PMID:18253097;PMID:27881117;PMID:2844226;PMID:2851993;PMID:30711981;PMID:6293548;PMID:7585520;PMID:8132610;PMID:8430079;PMID:8910369;PMID:9684876 -3.1.3.48 * leishmania major 55000.0 1 PMID:17005559 -3.1.3.48 * mammalia 18000.0 1 PMID:12169024 -3.1.3.48 * metarhizium anisopliae 82500.0 1 PMID:16926509 -3.1.3.48 * mycobacterium tuberculosis 30000.0 3 PMID:10986245;PMID:22888002 -3.1.3.48 * periplaneta americana 70000.0 1 PMID:16921521 -3.1.3.48 * plasmodium falciparum 25000.0 1 PMID:18096253 -3.1.3.48 * rattus norvegicus 269800.0 19 PMID:11170399;PMID:12745253;PMID:15802228;PMID:16946481;PMID:16973135;PMID:17005559;PMID:17224080;PMID:18342392;PMID:18445231;PMID:19137382;PMID:23711960;PMID:2851993;PMID:3002377;PMID:3026366;PMID:6293548;PMID:7843407;PMID:9016795 -3.1.3.48 * setaria cervi 21000.0 1 PMID:26341797 -3.1.3.48 * streptococcus pneumoniae d39 15800.0 1 PMID:29485030 -3.1.3.48 * streptomyces coelicolor 21000.0 2 PMID:16151248;PMID:8550407 -3.1.3.48 * thermus thermophilus 22260.0 2 PMID:19657570 -3.1.3.48 * trypanosoma cruzi 21000.0 1 PMID:16151248;PMID:8550407 -3.1.3.48 * yersinia enterocolitica 74000.0 4 PMID:1429715 -3.1.3.48 * yersinia sp. (in: enterobacteria) 33512.0 1 PMID:18781746 -3.1.3.48 * zea mays 42000.0 1 PMID:22529284 -3.1.3.5 * arachis hypogaea 55000.0 4 * -3.1.3.5 * bacillus sp. (in: firmicutes) 78000.0 1 * -3.1.3.5 * bacillus subtilis 65000.0 1 PMID:27907199 -3.1.3.5 * bos taurus 140000.0 8 PMID:10825541;PMID:12608891;PMID:15606776;PMID:2831062;PMID:6317380 -3.1.3.5 * cajanus cajan 119000.0 2 * -3.1.3.5 * cavia porcellus 185000.0 2 PMID:2986711 -3.1.3.5 * columba livia 150000.0 2 PMID:15940349;PMID:2344353 -3.1.3.5 * dosidicus gigas 107000.0 2 * -3.1.3.5 * escherichia coli 66000.0 2 PMID:6275004 -3.1.3.5 * gadus macrocephalus 270000.0 2 * -3.1.3.5 * gallus gallus 205000.0 3 PMID:3028048;PMID:945752 -3.1.3.5 * gloydius brevicauda 64480.0 2 PMID:19463842 -3.1.3.5 * haemophilus influenzae 66200.0 2 PMID:10768940 -3.1.3.5 * helicobacter pylori 72000.0 2 PMID:14680961 -3.1.3.5 * homo sapiens 210000.0 15 PMID:10092873;PMID:11133996;PMID:17405878;PMID:17680797;PMID:18641267;PMID:18684110;PMID:1998727;PMID:2173922;PMID:22997138;PMID:2844789 -3.1.3.5 * macrovipera lebetinus 120000.0 1 PMID:25434533 -3.1.3.5 * mus musculus 150000.0 9 PMID:14687921;PMID:16412684;PMID:2546926;PMID:4721620;PMID:9675234 -3.1.3.5 * phaseolus vulgaris 32000.0 2 PMID:32024086 -3.1.3.5 * rattus norvegicus 286000.0 22 PMID:1480162;PMID:1786854;PMID:18641267;PMID:18684110;PMID:2820949;PMID:6271180;PMID:6284244;PMID:8764609 -3.1.3.5 * salinivibrio costicola 70000.0 1 PMID:6163762 -3.1.3.5 * sebastes inermis 265000.0 5 * -3.1.3.5 * sus scrofa 130000.0 1 PMID:28225 -3.1.3.5 * torpedo marmorata 131000.0 2 PMID:2822031 -3.1.3.5 * trichinella spiralis 67000.0 1 PMID:15478804 -3.1.3.5 * vibrio parahaemolyticus 72000.0 1 PMID:14687921;PMID:2546926 -3.1.3.5 * xylella fastidiosa 74300.0 2 PMID:23474016 -3.1.3.5 * zea mays 49000.0 3 * -3.1.3.50 * malus domestica 61000.0 1 * -3.1.3.51 * rattus norvegicus 300000.0 1 PMID:6329308 -3.1.3.51 * sus scrofa 33000.0 1 PMID:9565603 -3.1.3.51 * tetrahymena pyriformis 500000.0 2 PMID:6274325 -3.1.3.52 * bos taurus 460000.0 4 PMID:2853819;PMID:3031042;PMID:6589597 -3.1.3.53 * badhamia polycephala 50000.0 1 PMID:20388117 -3.1.3.53 * gallus gallus 230000.0 11 PMID:11448958;PMID:1336455;PMID:7982954;PMID:9200713;PMID:9428658 -3.1.3.53 * homo sapiens 130000.0 4 PMID:18782776;PMID:19120700 -3.1.3.53 * mammalia 130000.0 1 PMID:16431080 -3.1.3.53 * meleagris gallopavo 230000.0 12 PMID:2842609;PMID:6304072;PMID:9054394 -3.1.3.53 * oryctolagus cuniculus 110000.0 1 PMID:2844285 -3.1.3.53 * sus scrofa 110000.0 3 PMID:8706736 -3.1.3.54 * saccharomyces cerevisiae 120000.0 2 PMID:2951255 -3.1.3.55 * gallus gallus 60000.0 3 PMID:8392339 -3.1.3.56 * arabidopsis sp. 64900.0 1 PMID:12805629 -3.1.3.56 * bos taurus 115000.0 9 PMID:1312931;PMID:1649601;PMID:2472292;PMID:2540972;PMID:8110204;PMID:8185320;PMID:8626616;PMID:8662625 -3.1.3.56 * canis lupus familiaris 47680.0 1 * -3.1.3.56 * homo sapiens 90100.0 4 PMID:1312931;PMID:1649601;PMID:17537645;PMID:2472292;PMID:2542294;PMID:8110204;PMID:8626616;PMID:8662625 -3.1.3.56 * mus musculus 48000.0 1 PMID:15468068 -3.1.3.56 * rattus norvegicus 160000.0 3 PMID:10593988;PMID:2826417 -3.1.3.56 * saccharomyces cerevisiae 115000.0 1 PMID:10962003 -3.1.3.56 * sus scrofa 81000.0 2 PMID:2540972;PMID:8185320 -3.1.3.57 * bos taurus 44000.0 2 PMID:2546770;PMID:2824473 -3.1.3.57 * gossypium hirsutum 37000.0 1 PMID:20331428 -3.1.3.57 * rattus norvegicus 58000.0 2 PMID:2848493;PMID:3039989 -3.1.3.58 * lacticaseibacillus casei 62000.0 2 PMID:2993253 -3.1.3.6 * crithidia luciliae 43000.0 1 PMID:11451370;PMID:2158995;PMID:7630383 -3.1.3.6 * flammulina velutipes 147000.0 1 * -3.1.3.6 * hordeum vulgare 36000.0 1 PMID:16665113 -3.1.3.6 * lathyrus oleraceus 30200.0 2 PMID:3036008 -3.1.3.6 * leishmania donovani 52159.0 3 PMID:11451370;PMID:2158995;PMID:7630383 -3.1.3.6 * leishmania infantum 43000.0 1 PMID:11451370 -3.1.3.6 * leishmania major 43000.0 1 PMID:11451370 -3.1.3.6 * leishmania mexicana 41670.0 2 PMID:11451370;PMID:11849641 -3.1.3.6 * leishmania tropica 43000.0 1 PMID:11451370;PMID:2158995;PMID:7630383 -3.1.3.6 * penicillium sp. 35000.0 3 PMID:1964878 -3.1.3.6 * solanum tuberosum 34200.0 2 PMID:5004159 -3.1.3.6 * tricholoma matsutake 38000.0 1 PMID:20057129 -3.1.3.60 * allium cepa 240000.0 2 PMID:16667434 -3.1.3.60 * brassica nigra 60000.0 3 PMID:16666836;PMID:16667434;PMID:1897950 -3.1.3.60 * brassica rapa subsp. oleifera 62000.0 1 * -3.1.3.60 * vigna radiata 240000.0 3 PMID:16667434;PMID:16668551;PMID:1897950 -3.1.3.62 * gallus gallus 64000.0 1 PMID:16759730 -3.1.3.62 * homo sapiens 70000.0 5 PMID:10087200;PMID:18413611;PMID:9923613 -3.1.3.62 * lilium longiflorum 53800.0 2 PMID:16860350 -3.1.3.62 * mus musculus 54500.0 1 PMID:10087200 -3.1.3.62 * rattus norvegicus 70000.0 6 PMID:1653239;PMID:18413611;PMID:2173549;PMID:7832765 -3.1.3.62 * sus scrofa 36000.0 1 PMID:2173549;PMID:7832765 -3.1.3.63 * nicotiana tabacum 53000.0 1 PMID:16666827 -3.1.3.63 * phaseolus vulgaris 56000.0 1 * -3.1.3.64 * homo sapiens 115000.0 2 PMID:11504939;PMID:19038970 -3.1.3.64 * mus musculus 165000.0 2 PMID:23188820;PMID:31543504 -3.1.3.64 * rattus norvegicus 147000.0 5 PMID:1655747 -3.1.3.66 * homo sapiens 105700.0 2 PMID:10097090;PMID:7608176 -3.1.3.66 * rattus norvegicus 105600.0 1 PMID:7608176 -3.1.3.67 * bos taurus 120000.0 1 PMID:8681945 -3.1.3.67 * rattus norvegicus 50000.0 1 PMID:17562371 -3.1.3.69 * synechocystis sp. 46000.0 1 PMID:9045835 -3.1.3.7 * arabidopsis thaliana 375000.0 1 PMID:8721754 -3.1.3.7 * debaryomyces hansenii 44000.0 1 PMID:16467467 -3.1.3.7 * escherichia coli 28000.0 1 PMID:17616624 -3.1.3.7 * gossypium hirsutum 37000.0 1 PMID:20331428 -3.1.3.7 * homo sapiens 33000.0 1 PMID:10675562 -3.1.3.7 * limnospira platensis 41800.0 1 PMID:16391050 -3.1.3.7 * mycobacterium tuberculosis 30000.0 1 PMID:18454554 -3.1.3.7 * oryza sativa 47000.0 2 PMID:7493934 -3.1.3.7 * rattus norvegicus 38000.0 1 PMID:2166593 -3.1.3.7 * schizosaccharomyces pombe 40000.0 1 PMID:10850973;PMID:11278717 -3.1.3.7 * zea mays 40000.0 2 PMID:10850973;PMID:11278717 -3.1.3.70 * palaeococcus ferrophilus 27130.0 2 PMID:16332790 -3.1.3.70 * thermus thermophilus 56400.0 3 PMID:12788726;PMID:21393850 -3.1.3.71 * clostridium acetobutylicum 26010.0 1 PMID:16927339 -3.1.3.71 * methanocaldococcus jannaschii 30000.0 1 PMID:11589710 -3.1.3.72 * lilium longiflorum 118000.0 2 PMID:16198125;PMID:16665018 -3.1.3.72 * sporolactobacillus laevolacticus 46000.0 2 PMID:16967265 -3.1.3.73 * salmonella enterica subsp. enterica serovar typhimurium 26000.0 1 PMID:7929373 -3.1.3.74 * bos taurus 33000.0 1 PMID:16336786 -3.1.3.74 * brachylagus idahoensis 33000.0 1 PMID:16336786 -3.1.3.74 * canis lupus familiaris 33000.0 1 PMID:16336786 -3.1.3.74 * felis catus 33000.0 1 PMID:16336786 -3.1.3.74 * gallus gallus 33000.0 1 PMID:16336786 -3.1.3.74 * homo sapiens 64000.0 9 PMID:1322411;PMID:14522954;PMID:15452547;PMID:16336786;PMID:18510874;PMID:7625842;PMID:8053678;PMID:8132548 -3.1.3.74 * mus musculus 33000.0 2 PMID:14522954;PMID:16336786 -3.1.3.74 * nicotiana tabacum 160000.0 1 PMID:30471733 -3.1.3.74 * paenibacillus thiaminolyticus 90000.0 3 PMID:16336194 -3.1.3.74 * rattus norvegicus 33000.0 1 PMID:16336786 -3.1.3.74 * schistosoma mansoni 31915.0 1 PMID:33613557 -3.1.3.74 * sinorhizobium meliloti 29000.0 2 PMID:16377884;PMID:18256491 -3.1.3.74 * sus scrofa 33000.0 1 PMID:16336786 -3.1.3.75 * arabidopsis thaliana 64000.0 3 PMID:22024570 -3.1.3.75 * gallus gallus 33000.0 4 PMID:15050893;PMID:9990301 -3.1.3.75 * homo sapiens 32000.0 2 PMID:14983068;PMID:15175005 -3.1.3.75 * mus musculus 29000.0 1 PMID:17227223 -3.1.3.75 * pseudomonas aeruginosa 74600.0 4 PMID:20064618;PMID:20693680 -3.1.3.77 * klebsiella pneumoniae 28300.0 4 PMID:8227039;PMID:8227040 -3.1.3.8 * agaricus bisporus 531000.0 1 PMID:15675798 -3.1.3.8 * amycolatopsis vancoresmycina 53000.0 1 * -3.1.3.8 * arabidopsis thaliana 60000.0 2 PMID:19633233 -3.1.3.8 * aspergillus awamori 84000.0 2 PMID:16243522 -3.1.3.8 * aspergillus ficuum 100000.0 7 PMID:10964658;PMID:12659840;PMID:19717291;PMID:20144543;PMID:28527994;PMID:3035533 -3.1.3.8 * aspergillus fumigatus 100000.0 15 PMID:10679211;PMID:10964658;PMID:17385337;PMID:17534560;PMID:9143104;PMID:9925554 -3.1.3.8 * aspergillus nidulans 86940.0 4 PMID:9925554 -3.1.3.8 * aspergillus niger 200000.0 26 PMID:12653285;PMID:12693443;PMID:15776271;PMID:16243522;PMID:17958557;PMID:18446871;PMID:19530713;PMID:20541524;PMID:8387447;PMID:9449782;PMID:9710894;PMID:9821286;PMID:9925554 -3.1.3.8 * aspergillus oryzae 65500.0 1 PMID:20144543;PMID:28527994 -3.1.3.8 * aspergillus sp. 84000.0 1 PMID:16243522 -3.1.3.8 * aspergillus terreus 230000.0 12 PMID:12693443;PMID:9821286;PMID:9925554 -3.1.3.8 * bacillus licheniformis 47000.0 1 PMID:12111145;PMID:14514072;PMID:19530713 -3.1.3.8 * bacillus sp. (in: firmicutes) 46000.0 4 PMID:11594462;PMID:12693443;PMID:18479345;PMID:9169005 -3.1.3.8 * bacillus subtilis 47500.0 8 PMID:12111145;PMID:12693443;PMID:18543132;PMID:20601512;PMID:24073799;PMID:9603817;PMID:9821286 -3.1.3.8 * burkholderia sp. a13(2014) 44000.0 1 PMID:25833676 -3.1.3.8 * citrobacter braakii 47000.0 1 PMID:12111145;PMID:14514072;PMID:19530713 -3.1.3.8 * corylus avellana 72000.0 2 PMID:13679091 -3.1.3.8 * debaryomyces castellii 77000.0 9 PMID:18046551;PMID:18242101 -3.1.3.8 * dendroctonus frontalis 51700.0 1 PMID:26536874 -3.1.3.8 * enterobacter sp. acss 62000.0 1 PMID:27250653 -3.1.3.8 * escherichia coli 53000.0 7 PMID:12111145;PMID:12693443;PMID:14514072;PMID:19530713;PMID:23794051;PMID:9821286;PMID:9925554 -3.1.3.8 * glycine max 130000.0 1 PMID:11500558 -3.1.3.8 * hordeum vulgare 66000.0 2 PMID:21220762 -3.1.3.8 * janthinobacterium sp. 64000.0 1 PMID:21562981 -3.1.3.8 * klebsiella aerogenes 700000.0 2 PMID:9821286 -3.1.3.8 * klebsiella oxytoca 490000.0 1 PMID:12693443;PMID:9821286 -3.1.3.8 * klebsiella sp. 112000.0 2 PMID:14727093;PMID:2162321 -3.1.3.8 * kodamaea ohmeri 98200.0 4 PMID:18040741;PMID:18672057 -3.1.3.8 * lilium longiflorum 56200.0 2 PMID:20655385 -3.1.3.8 * lupinus albus 65000.0 4 PMID:12405788 -3.1.3.8 * morchella importuna 61089.0 1 PMID:29017237 -3.1.3.8 * niallia nealsonii 43000.0 1 PMID:24073799;PMID:9603817 -3.1.3.8 * nicotiana tabacum 64000.0 2 PMID:17897689 -3.1.3.8 * obesumbacterium proteus 45000.0 1 PMID:14629009;PMID:15251209 -3.1.3.8 * pantoea agglomerans 42000.0 1 PMID:15648978 -3.1.3.8 * pantoea sp. 3.5.1 57000.0 1 PMID:26209662 -3.1.3.8 * pectobacterium carotovorum 45300.0 1 PMID:19884763 -3.1.3.8 * pectobacterium wasabiae 45000.0 1 PMID:18667849 -3.1.3.8 * penicillium camemberti 81000.0 1 PMID:12693443;PMID:9821286 -3.1.3.8 * penicillium caseoicolum 81000.0 1 PMID:12693443;PMID:9821286 -3.1.3.8 * penicillium simplicissimum 65000.0 1 PMID:11271818 -3.1.3.8 * pseudomonas sp. 68852.0 1 PMID:25112322 -3.1.3.8 * pseudomonas syringae 45000.0 1 PMID:14629009;PMID:15251209 -3.1.3.8 * raoultella terrigena 40000.0 1 PMID:12693443;PMID:9169005 -3.1.3.8 * rhizopus microsporus var. oligosporus 124000.0 3 PMID:15163521 -3.1.3.8 * schwanniomyces castellii 490000.0 1 PMID:12693443;PMID:9821286 -3.1.3.8 * schwanniomyces occidentalis 490000.0 1 PMID:12693443;PMID:9821286 -3.1.3.8 * selenomonas ruminantium 46000.0 1 * -3.1.3.8 * serratia sp. (in: enterobacteria) 66000.0 2 PMID:21853317 -3.1.3.8 * thermomyces dupontii 136100.0 3 PMID:9925554 -3.1.3.8 * thermothelomyces heterothallicus 73800.0 4 PMID:9925554 -3.1.3.8 * triticum aestivum 66000.0 3 PMID:21220762 -3.1.3.8 * uncultured bacterium 42000.0 1 PMID:25588560 -3.1.3.8 * volvariella volvacea 14000.0 1 PMID:22435144 -3.1.3.8 * wickerhamomyces anomalus 384000.0 3 PMID:12693443;PMID:20730601 -3.1.3.8 * yersinia enterocolitica 45000.0 1 PMID:21380516 -3.1.3.8 * yersinia frederiksenii 46000.0 2 PMID:19378262 -3.1.3.8 * yersinia kristensenii 48000.0 2 * -3.1.3.8 * yersinia pestis 46000.0 2 PMID:18548246 -3.1.3.8 * yersinia rohdei 46100.0 2 PMID:18548246 -3.1.3.8 * zea mays 66000.0 1 PMID:21220762 -3.1.3.82 * bordetella bronchiseptica 20000.0 1 PMID:20050614 -3.1.3.82 * escherichia coli 24900.0 2 PMID:11751812;PMID:20050614 -3.1.3.84 * saccharomyces cerevisiae 27000.0 1 PMID:15684411 -3.1.3.84 * severe acute respiratory syndrome-related coronavirus 19520.0 1 PMID:16271890 -3.1.3.85 * persephonella marina 39160.0 2 PMID:17189358 -3.1.3.86 * homo sapiens 170000.0 11 PMID:10194451;PMID:11349134;PMID:16302969;PMID:33421554;PMID:7556092;PMID:8643691;PMID:8654924;PMID:8968500;PMID:9341117;PMID:9824312 -3.1.3.86 * mus musculus 150000.0 2 PMID:16302969;PMID:8643691;PMID:8654924;PMID:8968500;PMID:9341117 -3.1.3.86 * rattus norvegicus 145000.0 1 PMID:8643691;PMID:8968500;PMID:9341117 -3.1.3.87 * klebsiella pneumoniae 28300.0 2 PMID:8227039 -3.1.3.89 * escherichia coli 100000.0 4 PMID:15489502 -3.1.3.9 * aspergillus oryzae 60800.0 1 PMID:4358816 -3.1.3.9 * felis catus 40770.0 1 PMID:17852328 -3.1.3.9 * homo sapiens 41000.0 3 PMID:11739393;PMID:12093795;PMID:12965222 -3.1.3.9 * oryctolagus cuniculus 18500.0 2 PMID:6293458 -3.1.3.9 * rattus norvegicus 70000.0 3 PMID:169241;PMID:2830258 -3.1.3.9 * sparus aurata 39251.0 1 PMID:15193269 -3.1.3.91 * drosophila melanogaster 40000.0 3 PMID:23223233 -3.1.3.91 * homo sapiens 34400.0 2 PMID:23223233 -3.1.3.93 * actinidia deliciosa 65000.0 2 PMID:15550539 -3.1.3.93 * arabidopsis thaliana 39700.0 3 PMID:15550539;PMID:19339506 -3.1.3.93 * nicotiana tabacum 58000.0 1 PMID:22790939 -3.1.3.94 * bos taurus 58000.0 2 PMID:9462881 -3.1.3.94 * rattus norvegicus 29000.0 1 PMID:9462881 -3.1.3.95 * homo sapiens 133000.0 2 PMID:25659891;PMID:25760698 -3.1.3.96 * homo sapiens 26000.0 1 PMID:20722631 -3.1.3.99 * saccharomyces cerevisiae 220000.0 2 PMID:8141771 -3.1.30.1 * aspergillus oryzae 60000.0 6 PMID:12586391;PMID:3021229;PMID:4691350;PMID:4722909;PMID:6252849;PMID:8597544;PMID:8955892 -3.1.30.1 * bacillus subtilis 57000.0 2 PMID:416955 -3.1.30.1 * badhamia polycephala 32000.0 1 * -3.1.30.1 * escherichia coli 20000.0 1 PMID:10498713 -3.1.30.1 * homo sapiens 54000.0 1 PMID:620006 -3.1.30.1 * lathyrus oleraceus 54000.0 4 PMID:3036008;PMID:41480 -3.1.30.1 * leishmania pifanoi 35000.0 1 PMID:10969068 -3.1.30.1 * mus musculus 76000.0 2 PMID:1009968;PMID:3027656 -3.1.30.1 * neurospora crassa 90000.0 3 * -3.1.30.1 * oryza sativa 26000.0 1 * -3.1.30.1 * penicillium citrinum 50000.0 2 * -3.1.30.1 * penicillium melinii 35000.0 1 PMID:21647618 -3.1.30.1 * schizophyllum commune 35000.0 2 * -3.1.30.1 * schizosaccharomyces pombe 32000.0 1 PMID:3021229;PMID:4691350;PMID:8955892 -3.1.30.1 * secale cereale 45000.0 1 PMID:6157530 -3.1.30.1 * triticum aestivum 43000.0 2 PMID:16594032 -3.1.30.1 * vigna radiata var. radiata 43000.0 4 PMID:41480;PMID:6246351 -3.1.30.2 * camellia sinensis 35000.0 2 * -3.1.30.2 * hordeum vulgare 37000.0 3 PMID:2822411;PMID:6249375 -3.1.30.2 * lentinula edodes 31000.0 1 PMID:7613009 -3.1.30.2 * mycolicibacterium smegmatis 43000.0 1 PMID:16584627 -3.1.30.2 * nicotiana tabacum 35000.0 1 PMID:4371779 -3.1.30.2 * podospora anserina 49000.0 1 PMID:17188431 -3.1.30.2 * serratia marcescens 26710.0 3 PMID:8373817 -3.1.30.2 * thinopyrum elongatum 36000.0 2 PMID:15596099 -3.1.31.1 * caenorhabditis elegans 136000.0 1 PMID:29440319 -3.1.31.1 * penaeus monodon 126000.0 2 PMID:23333357 -3.1.31.1 * plasmodium falciparum 110000.0 2 PMID:18035357 -3.1.31.1 * staphylococcus aureus 17000.0 5 PMID:13860347;PMID:20304012;PMID:24549181;PMID:5922961 -3.1.4.1 * aspergillus niger 62000.0 1 * -3.1.4.1 * badhamia polycephala 45300.0 1 PMID:3017212 -3.1.4.1 * beta vulgaris 110000.0 1 PMID:4333586 -3.1.4.1 * bos taurus 125000.0 4 PMID:170964;PMID:33895190;PMID:8387370 -3.1.4.1 * daucus carota 115000.0 1 PMID:4313739 -3.1.4.1 * escherichia coli 79400.0 1 PMID:17586769 -3.1.4.1 * flammulina velutipes 53000.0 1 * -3.1.4.1 * homo sapiens 430000.0 13 PMID:18199690;PMID:25288789;PMID:2822685;PMID:2986968;PMID:8001561;PMID:8275552;PMID:9722024 -3.1.4.1 * hordeum vulgare 100000.0 2 PMID:7687182 -3.1.4.1 * lupinus luteus 65000.0 2 PMID:6309793 -3.1.4.1 * mus musculus 240000.0 9 PMID:1647027;PMID:19741056;PMID:25288789;PMID:2839240;PMID:2992498;PMID:8001561;PMID:8223581 -3.1.4.1 * oryza sativa 70000.0 1 * -3.1.4.1 * rattus norvegicus 500000.0 6 PMID:11519884;PMID:7532398 -3.1.4.11 * amycolatopsis sp. nt115 54000.0 1 PMID:37015872 -3.1.4.11 * arabidopsis thaliana 95000.0 2 PMID:11377433 -3.1.4.11 * bos taurus 271000.0 6 PMID:3475691;PMID:6316925 -3.1.4.11 * capsicum chinense 44000.0 3 PMID:19513191 -3.1.4.11 * catharanthus roseus 44000.0 1 PMID:19513191 -3.1.4.11 * coffea arabica 34700.0 2 PMID:19513191 -3.1.4.11 * dictyostelium discoideum 91000.0 1 PMID:11015615 -3.1.4.11 * digitaria sanguinalis 70800.0 1 PMID:12021300 -3.1.4.11 * glycine max 64000.0 1 PMID:12132576 -3.1.4.11 * homo sapiens 260000.0 7 PMID:11395409;PMID:1333955;PMID:15702972;PMID:1646808;PMID:2829827 -3.1.4.11 * lathyrus oleraceus 67440.0 1 PMID:14564506 -3.1.4.11 * mammalia 85000.0 1 PMID:11395409 -3.1.4.11 * mus musculus 115000.0 5 PMID:14701816;PMID:15702972;PMID:3493241 -3.1.4.11 * rattus norvegicus 255000.0 11 PMID:11179219;PMID:1651335;PMID:18390926;PMID:19225867 -3.1.4.11 * saccharomyces cerevisiae 100600.0 1 PMID:8395015 -3.1.4.11 * toxoplasma gondii 121000.0 1 PMID:16288600 -3.1.4.11 * trypanosoma cruzi 82000.0 2 PMID:10692446 -3.1.4.11 * vigna radiata 67400.0 1 PMID:14706839 -3.1.4.12 * bacillus cereus 41000.0 5 PMID:12069857;PMID:14728687;PMID:23854;PMID:6284239 -3.1.4.12 * bos taurus 600000.0 8 PMID:10713073;PMID:10936181;PMID:12401200;PMID:12885774;PMID:19968763;PMID:2838331 -3.1.4.12 * danio rerio 46900.0 1 PMID:18678863 -3.1.4.12 * entamoeba histolytica 37000.0 2 PMID:20138872 -3.1.4.12 * helicobacter pylori 32000.0 1 PMID:16981685 -3.1.4.12 * homo sapiens 467600.0 48 PMID:10407147;PMID:10563319;PMID:10601312;PMID:10681556;PMID:10823942;PMID:10832103;PMID:11162568;PMID:12631268;PMID:12885774;PMID:16918;PMID:16981685;PMID:18052040;PMID:18567738;PMID:18989780;PMID:19083;PMID:20430951;PMID:22558155;PMID:2439128;PMID:2541739;PMID:2825797;PMID:2838331;PMID:33957567;PMID:6274305;PMID:6292172;PMID:6311712;PMID:8307965;PMID:8985151;PMID:9328299;PMID:9764481 -3.1.4.12 * listeria ivanovii 35500.0 1 PMID:16390439 -3.1.4.12 * listeria monocytogenes 33000.0 1 PMID:34709730 -3.1.4.12 * loxosceles laeta 33000.0 1 PMID:15159572 -3.1.4.12 * mus musculus 100000.0 10 PMID:10625655;PMID:10681556;PMID:20378533;PMID:25287744;PMID:6311712 -3.1.4.12 * oryctolagus cuniculus 92000.0 2 PMID:9879667 -3.1.4.12 * pseudomonas aeruginosa 78500.0 2 PMID:23201280 -3.1.4.12 * pseudomonas sp. 58110.0 1 PMID:11751833 -3.1.4.12 * rattus norvegicus 220000.0 8 PMID:10681556;PMID:10832103;PMID:11861674;PMID:37305954;PMID:6192193;PMID:9852115 -3.1.4.12 * staphylococcus aureus 33000.0 2 PMID:15159572 -3.1.4.12 * streptomyces griseocarneus 38000.0 3 PMID:19716517 -3.1.4.12 * streptomyces sp. 41540.0 3 PMID:22664344 -3.1.4.12 * trypanosoma brucei 81000.0 1 PMID:20398210 -3.1.4.14 * escherichia coli 25000.0 1 PMID:2168383 -3.1.4.16 * bacillus sp. (in: firmicutes) 122000.0 2 * -3.1.4.16 * haemophilus influenzae 79000.0 1 PMID:2997367 -3.1.4.16 * myxococcus xanthus 34000.0 1 PMID:19114044 -3.1.4.16 * salmonella enterica subsp. enterica serovar typhimurium 67000.0 1 PMID:15982 -3.1.4.16 * solanum lycopersicum 75000.0 2 PMID:10677447 -3.1.4.16 * staphylococcus aureus 23000.0 1 PMID:31422053 -3.1.4.16 * vibrio alginolyticus 65000.0 1 PMID:4303200 -3.1.4.16 * yersinia enterocolitica 71958.0 2 PMID:11160814 -3.1.4.17 * arthrobacter sp. 38000.0 3 PMID:23456275 -3.1.4.17 * bos taurus 201000.0 9 PMID:22900295;PMID:2842619;PMID:2842621;PMID:6313664;PMID:8166665 -3.1.4.17 * canis lupus familiaris 150000.0 2 * -3.1.4.17 * homo sapiens 220000.0 20 PMID:11050148;PMID:16142372;PMID:17696499;PMID:17697115;PMID:6326810;PMID:6329099 -3.1.4.17 * mammalia 124000.0 1 PMID:2842619 -3.1.4.17 * myxococcus xanthus 34000.0 3 PMID:19114044;PMID:21317337 -3.1.4.17 * neurospora crassa 400000.0 4 PMID:2848723 -3.1.4.17 * rattus norvegicus 79000.0 6 PMID:16881052;PMID:18222493 -3.1.4.17 * sinorhizobium fredii 82000.0 7 * -3.1.4.17 * trypanosoma cruzi 103169.0 1 PMID:16336277 -3.1.4.17 * xenopus laevis 140000.0 2 PMID:6326810;PMID:6329099 -3.1.4.2 * bos taurus 14000.0 1 PMID:8139761 -3.1.4.2 * escherichia coli 75000.0 3 PMID:2829735 -3.1.4.2 * haemophilus influenzae 41820.0 1 PMID:18230042 -3.1.4.2 * klebsiella aerogenes 185700.0 5 PMID:16820687;PMID:17306828;PMID:17630782 -3.1.4.2 * mus musculus 81000.0 1 PMID:20576599 -3.1.4.2 * rattus sp. 105000.0 3 PMID:1651840;PMID:181064 -3.1.4.3 * aspergillus oryzae 55000.0 1 PMID:33609939 -3.1.4.3 * bacillus cereus 28500.0 4 PMID:10727235;PMID:4216738;PMID:9521750 -3.1.4.3 * bacillus thuringiensis 38000.0 1 PMID:23923568 -3.1.4.3 * bos taurus 152000.0 7 PMID:7799788 -3.1.4.3 * burkholderia pseudomallei 77000.0 1 PMID:17526847 -3.1.4.3 * chaetopterus variopedatus 150000.0 2 PMID:18951372 -3.1.4.3 * clostridium perfringens 47000.0 3 PMID:191435;PMID:6268935;PMID:6329100 -3.1.4.3 * homo sapiens 150000.0 8 PMID:11509606;PMID:15788404;PMID:18701477;PMID:8780678;PMID:9056492;PMID:9360711 -3.1.4.3 * legionella pneumophila 60090.0 2 PMID:23457299;PMID:3171547 -3.1.4.3 * listeria monocytogenes 56000.0 4 PMID:1904842;PMID:34709730;PMID:37838694 -3.1.4.3 * mus musculus 150000.0 1 * -3.1.4.3 * mycobacterium tuberculosis 38000.0 1 PMID:18535356 -3.1.4.3 * plasmodium falciparum 46000.0 1 PMID:11781362 -3.1.4.3 * pseudoalteromonas sp. 32000.0 1 PMID:18784905 -3.1.4.3 * pseudomonas aeruginosa 80000.0 9 PMID:12410824;PMID:14962039;PMID:2120196;PMID:3151209;PMID:6401709;PMID:6811552;PMID:8174749 -3.1.4.3 * pseudomonas chlororaphis subsp. aureofaciens 35000.0 1 PMID:241404 -3.1.4.3 * pseudomonas fluorescens 42000.0 2 PMID:18973676;PMID:8722307 -3.1.4.3 * rattus norvegicus 150000.0 2 * -3.1.4.3 * streptomyces hachijoensis 18000.0 1 PMID:5411 -3.1.4.3 * tetrahymena pyriformis 128000.0 2 PMID:8292995 -3.1.4.3 * thermococcus kodakarensis 54000.0 1 PMID:35854045 -3.1.4.3 * thermothielavioides terrestris 66300.0 3 PMID:32315679 -3.1.4.3 * trypanosoma brucei 39000.0 1 PMID:3782089 -3.1.4.35 * bombyx mori 260000.0 1 PMID:1092 -3.1.4.35 * bos taurus 178000.0 4 PMID:16938469;PMID:1697584;PMID:6286681;PMID:7799796 -3.1.4.35 * drosophila melanogaster 130000.0 1 PMID:18503409 -3.1.4.35 * homo sapiens 200000.0 5 PMID:15093609;PMID:17979301;PMID:18564357;PMID:19801642 -3.1.4.35 * mus musculus 182000.0 3 PMID:11389965;PMID:8389302 -3.1.4.35 * rattus norvegicus 400000.0 5 PMID:14501210;PMID:18986324;PMID:19760692;PMID:2842633;PMID:4346951 -3.1.4.35 * sus scrofa 100000.0 3 PMID:18669600 -3.1.4.37 * artemia sp. 55000.0 1 PMID:8645716 -3.1.4.37 * bacillus subtilis 74000.0 1 * -3.1.4.37 * bos taurus 120000.0 12 PMID:2537684;PMID:2836557;PMID:3029107;PMID:6253072;PMID:6258586;PMID:6263914;PMID:6269898 -3.1.4.37 * canis lupus familiaris 48000.0 2 PMID:2537684 -3.1.4.37 * cavia porcellus 48000.0 2 PMID:2537684 -3.1.4.37 * homo sapiens 250000.0 13 PMID:17963267;PMID:18676363;PMID:19508346;PMID:2537684;PMID:2835044;PMID:2836557 -3.1.4.37 * macaca mulatta 50000.0 2 PMID:17963267 -3.1.4.37 * mus musculus 78000.0 6 PMID:20180985;PMID:22393399;PMID:2537684 -3.1.4.37 * oryctolagus cuniculus 48000.0 2 PMID:2537684 -3.1.4.37 * ovis aries 48000.0 2 PMID:2537684 -3.1.4.37 * rattus norvegicus 100000.0 13 PMID:10646504;PMID:11032883;PMID:11278504;PMID:11356257;PMID:14503857;PMID:24532135;PMID:25100014;PMID:2537684;PMID:2836557;PMID:32370072;PMID:8011177 -3.1.4.37 * spinacia oleracea 263000.0 2 * -3.1.4.37 * sus scrofa 48000.0 6 PMID:2537684;PMID:6258586;PMID:6263914;PMID:8011177 -3.1.4.37 * triticum aestivum 24000.0 2 PMID:3654600 -3.1.4.38 * bos taurus 110000.0 4 PMID:10478944;PMID:23161088;PMID:8923480 -3.1.4.38 * mus musculus 170000.0 3 PMID:1326942;PMID:8139771 -3.1.4.38 * rattus norvegicus 230000.0 2 PMID:181064;PMID:2540950 -3.1.4.38 * streptomyces sanglieri 70447.0 2 PMID:24211038 -3.1.4.39 * gallus gallus 110000.0 1 PMID:17321793 -3.1.4.39 * hemiscorpius lepturus 33000.0 1 PMID:23562369 -3.1.4.39 * homo sapiens 125000.0 8 PMID:18175805;PMID:18249559;PMID:18485925;PMID:19139100 -3.1.4.39 * mus musculus 120000.0 7 PMID:17208043;PMID:18175805;PMID:18327261;PMID:18818380 -3.1.4.39 * rattus norvegicus 125000.0 8 PMID:15985467;PMID:16436050;PMID:17071136;PMID:17192809;PMID:17307740;PMID:20823545;PMID:21240271;PMID:21812758 -3.1.4.39 * streptomyces chromofuscus 125000.0 1 PMID:15769751 -3.1.4.39 * thermocrispum sp. 33000.0 1 PMID:37802209 -3.1.4.4 * actinomadura sp. 60000.0 1 * -3.1.4.4 * arabidopsis thaliana 124000.0 4 PMID:11706190;PMID:11891260;PMID:17098468 -3.1.4.4 * arachis hypogaea 200000.0 6 PMID:16703472 -3.1.4.4 * brassica napus 105000.0 1 * -3.1.4.4 * brassica oleracea 116600.0 5 PMID:17451436;PMID:518840;PMID:8528610 -3.1.4.4 * citrus sinensis 94200.0 1 PMID:3688883 -3.1.4.4 * daucus carota 60000.0 1 PMID:11237693 -3.1.4.4 * glycine max 92000.0 1 PMID:8353126 -3.1.4.4 * homo sapiens 120000.0 6 PMID:15206940;PMID:15774548 -3.1.4.4 * loxosceles intermedia 33000.0 2 PMID:18082635 -3.1.4.4 * oryza sativa 82000.0 1 PMID:7551587 -3.1.4.4 * paralichthys olivaceus 120500.0 1 PMID:18329902 -3.1.4.4 * pseudomonas aeruginosa 116000.0 1 PMID:11136451 -3.1.4.4 * rattus norvegicus 200000.0 4 PMID:11000525;PMID:16527816;PMID:489566 -3.1.4.4 * shewanella sp. 64000.0 1 PMID:17928713 -3.1.4.4 * streptomyces antibioticus 64000.0 1 * -3.1.4.4 * streptomyces chromofuscus 57000.0 1 PMID:762053 -3.1.4.4 * streptomyces cinnamoneus 54000.0 3 PMID:34585426;PMID:9990122 -3.1.4.4 * streptomyces hachijoensis 16000.0 1 PMID:6440 -3.1.4.4 * streptomyces lydicus 56000.0 1 * -3.1.4.4 * streptomyces olivochromogenes 60000.0 1 PMID:19039525;PMID:30989410 -3.1.4.4 * streptomyces racemochromogenes 55000.0 1 PMID:18038909;PMID:21082226 -3.1.4.4 * streptomyces sp. 60000.0 5 PMID:18038909;PMID:18930391;PMID:19039525;PMID:19229499;PMID:21082226;PMID:30989410 -3.1.4.4 * streptomyces tendae 43000.0 1 PMID:19898811 -3.1.4.4 * sus scrofa 190000.0 2 PMID:7797473;PMID:7983063 -3.1.4.4 * vigna radiata 150000.0 1 PMID:16661522 -3.1.4.4 * vigna unguiculata 90000.0 3 PMID:11161113;PMID:16949301 -3.1.4.4 * vitis vinifera 91800.0 1 PMID:17669277 -3.1.4.41 * corynebacterium pseudotuberculosis 31000.0 3 PMID:2403529;PMID:426767;PMID:8397477 -3.1.4.41 * loxosceles gaucho 70000.0 1 PMID:18784245 -3.1.4.41 * loxosceles intermedia 70000.0 3 PMID:16934304;PMID:18784245 -3.1.4.41 * loxosceles laeta 70000.0 3 PMID:18784245;PMID:19249326 -3.1.4.41 * loxosceles reclusa 34000.0 2 PMID:1965062;PMID:6274420 -3.1.4.41 * photobacterium damselae 69000.0 2 PMID:8397477 -3.1.4.42 * sus scrofa 35500.0 1 PMID:212014 -3.1.4.44 * homo sapiens 37700.0 1 PMID:17275818 -3.1.4.44 * rattus norvegicus 43000.0 1 PMID:12576545 -3.1.4.45 * bos taurus 272000.0 8 PMID:8294420;PMID:8294421;PMID:9722550 -3.1.4.45 * homo sapiens 156000.0 8 PMID:10551838;PMID:11408573;PMID:3019310;PMID:8922957 -3.1.4.46 * agrobacterium tumefaciens 160000.0 3 PMID:16909422 -3.1.4.46 * arabidopsis thaliana 45000.0 1 PMID:14750903 -3.1.4.46 * bacillus altitudinis 28000.0 1 PMID:33758739 -3.1.4.46 * borrelia recurrentis 39000.0 1 PMID:11015364 -3.1.4.46 * daucus carota 280000.0 2 PMID:14750903 -3.1.4.46 * escherichia coli 40000.0 5 PMID:18083802;PMID:1851953;PMID:24373430;PMID:2842304 -3.1.4.46 * escherichia coli k-12 27000.0 1 PMID:18083802 -3.1.4.46 * homo sapiens 69000.0 3 PMID:17578682;PMID:18991142 -3.1.4.46 * klebsiella aerogenes 3083993.0 5 PMID:14711669;PMID:16820687;PMID:18831553 -3.1.4.46 * mus musculus 68910.0 2 PMID:12933806;PMID:15276213 -3.1.4.46 * saccharomyces cerevisiae 138000.0 3 PMID:16172116;PMID:24373430 -3.1.4.46 * thermotoga maritima 25570.0 1 PMID:15162496 -3.1.4.50 * bos taurus 100000.0 1 PMID:7651182;PMID:9061000 -3.1.4.50 * homo sapiens 110000.0 2 PMID:10937880;PMID:7651182 -3.1.4.52 * escherichia coli 48000.0 2 PMID:15453820 -3.1.4.52 * pseudomonas aeruginosa 176400.0 3 PMID:17586641;PMID:18344366 -3.1.4.52 * shewanella woodyi 197200.0 5 PMID:24628400 -3.1.4.52 * thermotoga maritima 90000.0 1 PMID:26786892 -3.1.4.53 * homo sapiens 125000.0 4 PMID:12071709;PMID:17519386;PMID:18095939 -3.1.4.53 * leishmania mexicana 200000.0 2 PMID:10699257 -3.1.4.53 * marchantia polymorpha 46000.0 1 PMID:34779957 -3.1.4.53 * mus musculus 93000.0 8 PMID:10618442;PMID:11267656;PMID:18804162;PMID:8389302 -3.1.4.53 * myxococcus xanthus 34000.0 4 PMID:19114044 -3.1.4.53 * pseudomonas aeruginosa 31000.0 1 PMID:20348254 -3.1.4.53 * rattus norvegicus 87000.0 5 PMID:18222493;PMID:18227403 -3.1.4.53 * trypanosoma cruzi 102500.0 1 PMID:16776650 -3.1.4.54 * homo sapiens 45596.0 1 PMID:19126434 -3.1.4.54 * mus musculus 45816.0 1 PMID:19126434 -3.1.4.54 * rattus norvegicus 46000.0 2 PMID:15949819;PMID:16527816;PMID:17712822;PMID:19126434 -3.1.4.56 * methanocaldococcus jannaschii 370000.0 2 PMID:19746965 -3.1.4.60 * streptococcus mitis 92000.0 1 PMID:32825526 -3.1.4.62 * homo sapiens 56100.0 1 PMID:33621517 -3.1.5.1 * escherichia coli 230000.0 4 PMID:1657865;PMID:2826481 -3.1.5.1 * shigella boydii 59400.0 1 PMID:8995266 -3.1.6.1 * artemia salina 460000.0 3 * -3.1.6.1 * aspergillus oryzae 100000.0 3 PMID:241293;PMID:3732565;PMID:4685274 -3.1.6.1 * capra hircus 70000.0 1 PMID:18820837 -3.1.6.1 * carpodesmia tamariscifolia 166000.0 1 * -3.1.6.1 * chlamydomonas reinhardtii 150000.0 2 PMID:236768 -3.1.6.1 * citrobacter braakii 61600.0 1 PMID:37406746 -3.1.6.1 * eimeria tenella 49000.0 1 PMID:16345546;PMID:3109387 -3.1.6.1 * flammeovirga pacifica 56000.0 1 PMID:37406746 -3.1.6.1 * gallus gallus 105000.0 6 PMID:15246527;PMID:3109387;PMID:3732565;PMID:4685274;PMID:6884544 -3.1.6.1 * hemicentrotus pulcherrimus 670000.0 2 * -3.1.6.1 * homo sapiens 107000.0 5 PMID:18283100;PMID:23986440;PMID:240321 -3.1.6.1 * klebsiella aerogenes 45000.0 1 * -3.1.6.1 * littorina kurila 45000.0 1 PMID:16523723 -3.1.6.1 * marinomonas sp. fw-1 33000.0 1 PMID:37406746 -3.1.6.1 * mus musculus 56000.0 1 PMID:19536613 -3.1.6.1 * naja nigricollis 50000.0 1 PMID:37406746 -3.1.6.1 * pseudoalteromonas carrageenovora 33000.0 2 PMID:15596366 -3.1.6.1 * pseudomonas aeruginosa 60000.0 3 PMID:19554727;PMID:34952364;PMID:7744061 -3.1.6.1 * pyrococcus furiosus 90000.0 1 PMID:37406746 -3.1.6.1 * rattus norvegicus 64000.0 2 PMID:1861083;PMID:19536613 -3.1.6.1 * serratia marcescens 49000.0 2 PMID:16345546;PMID:3109387 -3.1.6.1 * serratia sp. sm1 60000.0 1 PMID:19554727;PMID:34952364 -3.1.6.1 * sphingomonas sp. 62000.0 2 PMID:14600791;PMID:37406746 -3.1.6.1 * sphingomonas sp. as6330 62000.0 2 PMID:14600791;PMID:37406746 -3.1.6.1 * streptomyces sp. 46500.0 1 PMID:7612993 -3.1.6.1 * thermotoga maritima 65000.0 2 PMID:37406746 -3.1.6.12 * bos taurus 60000.0 3 PMID:1009120;PMID:4723244 -3.1.6.12 * felis catus 100000.0 5 PMID:1397482;PMID:1632799;PMID:7130169;PMID:7857682 -3.1.6.12 * gallus gallus 47000.0 1 PMID:7370276 -3.1.6.12 * homo sapiens 61000.0 12 PMID:1397482;PMID:1632799;PMID:3435483;PMID:6010;PMID:7130169;PMID:7857682 -3.1.6.12 * mus musculus 60000.0 3 PMID:16570510;PMID:4084217 -3.1.6.12 * rattus norvegicus 84000.0 2 PMID:1397482;PMID:1632799;PMID:7857682 -3.1.6.13 * homo sapiens 190000.0 22 PMID:11731225;PMID:12393174;PMID:17655837;PMID:19556155;PMID:19602578;PMID:20000684;PMID:2222422;PMID:23625223;PMID:3857078;PMID:6816283;PMID:6945876;PMID:6954344;PMID:8424762;PMID:9337875 -3.1.6.14 * bos taurus 60200.0 3 PMID:8155645 -3.1.6.14 * capra hircus 94000.0 2 PMID:9355739 -3.1.6.14 * homo sapiens 100000.0 14 PMID:1463457;PMID:1546976;PMID:15595925;PMID:3689314;PMID:762121;PMID:9164838 -3.1.6.14 * pedobacter heparinus 61570.0 1 PMID:19726671 -3.1.6.14 * prevotella sp. 119000.0 1 PMID:10981693 -3.1.6.14 * rattus norvegicus 70000.0 1 PMID:3689315 -3.1.6.17 * pseudomonas syringae 89000.0 3 PMID:6497859 -3.1.6.18 * homo sapiens 69000.0 3 PMID:2497731;PMID:4019466 -3.1.6.19 * pseudomonas sp. 46000.0 2 PMID:7406859 -3.1.6.19 * rhodococcus ruber 67000.0 2 PMID:12732552 -3.1.6.2 * aspergillus nidulans 44000.0 1 PMID:3886594 -3.1.6.2 * bos taurus 180000.0 3 PMID:10925212 -3.1.6.2 * chlamydomonas reinhardtii 150000.0 1 PMID:3886594 -3.1.6.2 * homo sapiens 600000.0 24 PMID:11738554;PMID:12163138;PMID:1606923;PMID:16621525;PMID:16837617;PMID:17604157;PMID:18180093;PMID:2065092;PMID:2953589;PMID:3032454;PMID:3470015;PMID:3886594;PMID:6417417;PMID:6580511;PMID:6594315;PMID:7857878;PMID:9252398 -3.1.6.2 * mus musculus 128000.0 4 PMID:3479751;PMID:6417417;PMID:7857878 -3.1.6.2 * pseudomonas aeruginosa 60000.0 1 PMID:3886594 -3.1.6.2 * rattus norvegicus 280000.0 6 PMID:3886594;PMID:6959991;PMID:7200 -3.1.6.21 * escherichia coli 120000.0 1 PMID:25066955 -3.1.6.21 * pseudomonas sp. s9 147000.0 1 PMID:21318560 -3.1.6.21 * rhodococcus ruber 67000.0 1 PMID:12732552 -3.1.6.3 * charonia lampas 112000.0 2 PMID:7553 -3.1.6.3 * helicobacter pylori 30000.0 1 PMID:8518427 -3.1.6.3 * porphyromonas gingivalis 38000.0 1 PMID:8389637 -3.1.6.3 * prevotella sp. 111000.0 2 * -3.1.6.3 * pseudomonas carrageenovora 55000.0 1 PMID:520310 -3.1.6.4 * homo sapiens 120000.0 21 PMID:10814710;PMID:16378744;PMID:17027703;PMID:17336563;PMID:1794986;PMID:1953646;PMID:39554;PMID:7213753 -3.1.6.6 * penicillium chrysogenum 345000.0 1 PMID:4196744 -3.1.6.6 * pseudomonas aeruginosa 175000.0 1 PMID:4196744 -3.1.6.6 * sinorhizobium meliloti 240000.0 3 PMID:29458126;PMID:30338300 -3.1.6.8 * acipenser gueldenstaedtii 172000.0 1 PMID:15581789 -3.1.6.8 * bos taurus 107000.0 1 PMID:13772 -3.1.6.8 * homo sapiens 130000.0 13 PMID:13772;PMID:19864504;PMID:26845;PMID:804474;PMID:9521684 -3.1.6.8 * mus musculus 66000.0 1 PMID:18420734 -3.1.6.8 * oryctolagus cuniculus 140000.0 2 PMID:1352147;PMID:6104985 -3.1.6.8 * rattus norvegicus 123000.0 3 PMID:1363453;PMID:17067361 -3.1.6.8 * sus scrofa 68000.0 4 PMID:17050327;PMID:17474085 -3.1.7.11 * catharanthus roseus 67700.0 1 PMID:23102596 -3.1.7.11 * cinnamomum tenuipile 69000.0 1 PMID:15680985 -3.1.7.11 * ocimum basilicum 140000.0 3 PMID:14657409 -3.1.7.2 * bacillus subtilis 65000.0 1 PMID:114395 -3.1.7.2 * escherichia coli 260000.0 4 PMID:114395;PMID:374338 -3.1.7.2 * geobacillus stearothermophilus 65000.0 1 PMID:114395 -3.1.7.2 * streptococcus dysgalactiae subsp. equisimilis 48000.0 1 PMID:12003927 -3.1.7.3 * salvia officinalis 65000.0 2 PMID:42357 -3.1.7.5 * croton stellatopilosus 232000.0 4 PMID:16445953 -3.1.7.6 * saccharomyces cerevisiae 60000.0 1 PMID:16484724 -3.1.8.1 * bos taurus 66000.0 3 PMID:12946270;PMID:15805725;PMID:16457617;PMID:16600468;PMID:1673382;PMID:1673383;PMID:19084484;PMID:21883041;PMID:24563030;PMID:24907040 -3.1.8.1 * brevundimonas diminuta 82000.0 5 PMID:15790580;PMID:19548794;PMID:32814367 -3.1.8.1 * ectopseudomonas oleovorans 36000.0 1 PMID:16769224 -3.1.8.1 * flavobacterium sp. 40000.0 2 PMID:20132373;PMID:20457694;PMID:24858677;PMID:25107406;PMID:7945421 -3.1.8.1 * geobacillus stearothermophilus 36000.0 1 PMID:19615330 -3.1.8.1 * homo sapiens 380000.0 19 PMID:10421461;PMID:11369803;PMID:11579088;PMID:12946270;PMID:15772423;PMID:16457617;PMID:16600468;PMID:1673382;PMID:1673383;PMID:1718413;PMID:18355454;PMID:18640108;PMID:18649306;PMID:18952040;PMID:19084484;PMID:19103263;PMID:19902382;PMID:20132373;PMID:20176005;PMID:21123122;PMID:24907040;PMID:25107406;PMID:7945421;PMID:8403430;PMID:8565784;PMID:9032442 -3.1.8.1 * mus musculus 331000.0 2 PMID:20132373;PMID:25107406;PMID:7945421 -3.1.8.1 * pimelobacter simplex 45000.0 1 PMID:10772149 -3.1.8.1 * platynota idaeusalis 41000.0 1 PMID:11170316 -3.1.8.1 * plesiomonas sp. 35000.0 2 PMID:15249038 -3.1.8.1 * purpureocillium lilacinum 60000.0 1 * -3.1.8.1 * rattus norvegicus 45000.0 2 PMID:10421461;PMID:12946270;PMID:16457617;PMID:16600468;PMID:1673382;PMID:1673383;PMID:19084484;PMID:19103263;PMID:19902382;PMID:21123122;PMID:24907040;PMID:9032442 -3.1.8.1 * saccharolobus islandicus 80000.0 1 PMID:23071703 -3.1.8.1 * saccharolobus solfataricus 50000.0 7 PMID:15909078;PMID:18931117;PMID:21183649 -3.1.8.1 * scyliorhinus canicula 66000.0 1 PMID:21883041;PMID:24563030 -3.1.8.1 * stenotrophomonas sp. yc-1 32000.0 1 PMID:25917649 -3.1.8.1 * sulfolobus acidocaldarius 69100.0 3 PMID:17337320 -3.1.8.1 * vulcanisaeta moutnovskia 82000.0 2 PMID:20457694;PMID:24858677 -3.10.1.1 * homo sapiens 190000.0 12 PMID:21671382;PMID:3707548;PMID:518547;PMID:6849981;PMID:9405287 -3.10.1.1 * pedobacter heparinus 81500.0 1 PMID:3595605 -3.10.1.1 * rattus norvegicus 120000.0 1 PMID:4854485 -3.11.1.1 * achromobacter aegrifaciens 65000.0 1 PMID:38928116 -3.11.1.1 * achromobacter insolitus 65000.0 1 PMID:38928116 -3.11.1.1 * bacillus cereus 83000.0 2 PMID:4989158 -3.11.1.2 * penicillium oxalicum 43200.0 2 PMID:16129582 -3.11.1.2 * pseudomonas fluorescens 93000.0 5 PMID:21366328;PMID:8529644;PMID:9300819 -3.11.1.2 * sinorhizobium meliloti 48400.0 1 PMID:21543322 -3.11.1.3 * burkholderia cepacia 232000.0 1 PMID:10648102 -3.11.1.3 * variovorax sp. 110000.0 4 PMID:12697754;PMID:16981709 -3.12.1.1 * acidiphilium acidophilum 99000.0 2 PMID:1396709 -3.13.1.1 * arabidopsis thaliana 53100.0 2 PMID:11073956;PMID:9465123 -3.13.1.1 * spinacia oleracea 250000.0 4 PMID:12706349;PMID:21371504 -3.13.1.3 * paenibacillus sp. 39000.0 2 PMID:12743754 -3.13.1.3 * rhodococcus erythropolis 43000.0 3 PMID:12147352;PMID:12801508 -3.13.1.4 * advenella mimigardefordensis 175000.0 5 PMID:23354747;PMID:24317404 -3.13.1.4 * cupriavidus necator 175000.0 2 PMID:24317404 -3.13.1.4 * paraburkholderia xenovorans 172000.0 2 PMID:24317404 -3.13.1.4 * variovorax paradoxus 174000.0 2 PMID:24317404 -3.13.1.5 * acidianus sp. 24000.0 1 PMID:22012399 -3.13.1.7 * acidithiobacillus thiooxidans 384000.0 2 PMID:23836868 -3.13.1.9 * methanocaldococcus jannaschii 49000.0 1 PMID:25917907 -3.13.2.1 * alcaligenes faecalis 310000.0 4 PMID:6428887 -3.13.2.1 * bos taurus 237000.0 6 PMID:15645450;PMID:18804558;PMID:1975808;PMID:2987197;PMID:6091559;PMID:6293581;PMID:659427;PMID:8093102;PMID:8329449;PMID:8871889 -3.13.2.1 * branchiostoma belcheri tsingtauense 47800.0 1 PMID:18532926 -3.13.2.1 * corynebacterium efficiens 210000.0 2 PMID:18034499;PMID:18253021;PMID:7305945 -3.13.2.1 * corynebacterium glutamicum 210000.0 3 PMID:18034499;PMID:18253021;PMID:7305945 -3.13.2.1 * cryphonectria parasitica 49500.0 1 PMID:22889301 -3.13.2.1 * cryptosporidium parvum 244000.0 3 PMID:17559404 -3.13.2.1 * cytophaga hutchinsonii 200000.0 1 PMID:11134963;PMID:14969692 -3.13.2.1 * dictyostelium discoideum 190000.0 2 PMID:15645450;PMID:18804558;PMID:1975808;PMID:2987197;PMID:6091559;PMID:8093102;PMID:8329449;PMID:8871889 -3.13.2.1 * homo sapiens 260000.0 9 PMID:11134963;PMID:14969692;PMID:15645450;PMID:18211827;PMID:18804558;PMID:1975808;PMID:20208169;PMID:24430301;PMID:25248746;PMID:2987197;PMID:4052045;PMID:6091559;PMID:6639063;PMID:8093102;PMID:8329449;PMID:8871889 -3.13.2.1 * leishmania donovani 52000.0 1 PMID:22324915 -3.13.2.1 * lupinus luteus 200000.0 6 PMID:18607106;PMID:21137580;PMID:22349223;PMID:923592 -3.13.2.1 * mesocricetus auratus 200000.0 2 PMID:14969692;PMID:25248746;PMID:6639063 -3.13.2.1 * mus musculus 190000.0 5 PMID:15645450;PMID:18804558;PMID:1975808;PMID:20208169;PMID:24430301;PMID:2987197;PMID:6091559;PMID:6293581;PMID:8093102;PMID:8329449;PMID:8871889 -3.13.2.1 * mycobacterium tuberculosis 50000.0 1 PMID:23178568 -3.13.2.1 * plasmodium falciparum 200000.0 2 PMID:11134963;PMID:14969692 -3.13.2.1 * populus tomentosa 53360.0 2 PMID:25079429 -3.13.2.1 * pyrococcus furiosus 190000.0 4 PMID:15645450;PMID:18804558;PMID:1975808;PMID:2987197;PMID:6091559;PMID:8093102;PMID:8329449;PMID:8871889 -3.13.2.1 * rattus norvegicus 229000.0 8 PMID:15645450;PMID:18034499;PMID:18253021;PMID:18804558;PMID:1975808;PMID:2987197;PMID:6091559;PMID:7305945;PMID:7462216;PMID:8093102;PMID:8329449;PMID:8871889 -3.13.2.1 * saccharolobus solfataricus 190000.0 4 PMID:10648166;PMID:15645450;PMID:18804558;PMID:1975808;PMID:2987197;PMID:6091559;PMID:8093102;PMID:8329449;PMID:8871889;PMID:8921839 -3.13.2.1 * synechocystis sp. pcc 6803 184000.0 2 PMID:35775986 -3.13.2.1 * thermotoga maritima 180000.0 2 PMID:23588970 -3.13.2.1 * trichomonas vaginalis 55000.0 1 PMID:9769247 -3.13.2.1 * trypanosoma cruzi 200000.0 2 PMID:11134963;PMID:14969692;PMID:25248746;PMID:6639063 -3.2.1.1 * acanthoscelides obtectus 45000.0 2 PMID:15740044 -3.2.1.1 * alcaligenes faecalis 52000.0 1 PMID:23916704 -3.2.1.1 * alicyclobacillus acidocaldarius 160000.0 3 PMID:16347662;PMID:7813489;PMID:8836148 -3.2.1.1 * alkalimonas amylolytica 61160.0 2 PMID:12549000;PMID:17068753 -3.2.1.1 * anabaena sp. 56700.0 2 PMID:19756583 -3.2.1.1 * anoxybacillus sp. gxs-bl 55000.0 1 PMID:30652633 -3.2.1.1 * apis mellifera 57000.0 1 * -3.2.1.1 * ascaris suum 83000.0 3 PMID:11833785 -3.2.1.1 * aspergillus awamori 120000.0 4 * -3.2.1.1 * aspergillus niger 61000.0 3 * -3.2.1.1 * aspergillus oryzae 68000.0 7 PMID:12743761;PMID:16347662;PMID:7663414;PMID:8836148 -3.2.1.1 * bacillus amyloliquefaciens 195000.0 7 PMID:11524019;PMID:16581150;PMID:18769877;PMID:19763902;PMID:19841977;PMID:22561851;PMID:23916704;PMID:23923536;PMID:32871125 -3.2.1.1 * bacillus licheniformis 62650.0 7 PMID:11282629;PMID:11524019;PMID:16346366;PMID:17934774;PMID:25152412;PMID:26135919;PMID:29233713 -3.2.1.1 * bacillus mojavensis 58000.0 1 PMID:20108054 -3.2.1.1 * bacillus sp. (in: firmicutes) 94500.0 16 PMID:11162382;PMID:11282629;PMID:12856195;PMID:17920264;PMID:17934774;PMID:20109486;PMID:20471589;PMID:20552260;PMID:25152412;PMID:27377461;PMID:9726872;PMID:9805372 -3.2.1.1 * bacillus subtilis 205000.0 19 PMID:112102;PMID:118135;PMID:15043510;PMID:15866721;PMID:16347662;PMID:16850297;PMID:18062231;PMID:18157528;PMID:19728109;PMID:23916704;PMID:29561221 -3.2.1.1 * bacteria 87000.0 2 * -3.2.1.1 * brevibacillus brevis 27000.0 1 * -3.2.1.1 * carthamus tinctorius 35000.0 1 PMID:19393974 -3.2.1.1 * citrus sinensis 42000.0 1 PMID:19941088 -3.2.1.1 * clostridium butyricum 89000.0 1 * -3.2.1.1 * corallococcus coralloides 22500.0 1 * -3.2.1.1 * corallococcus sp. egb 60000.0 2 PMID:18375163;PMID:29752267 -3.2.1.1 * cryptococcus sp. (in: basidiomycete fungi) 66000.0 1 PMID:8836148 -3.2.1.1 * dioscorea dumetorum 52000.0 3 PMID:6153648 -3.2.1.1 * eisenia fetida 60000.0 1 PMID:18375163;PMID:29752267 -3.2.1.1 * eleusine coracana 47000.0 3 PMID:12475615;PMID:12834286;PMID:18025579 -3.2.1.1 * ephestia kuehniella 56000.0 2 PMID:19476481 -3.2.1.1 * euplotes focardii 52000.0 1 PMID:23916704 -3.2.1.1 * exiguobacterium sp. sh3 53000.0 1 * -3.2.1.1 * fusicoccum sp. 50000.0 1 PMID:17690465 -3.2.1.1 * fusidium sp. 53000.0 1 * -3.2.1.1 * gammarus palustris 69400.0 5 PMID:8590377 -3.2.1.1 * geobacillus sp. 97000.0 2 PMID:19874846;PMID:20094713 -3.2.1.1 * geobacillus sp. k1c 59000.0 1 PMID:29864538 -3.2.1.1 * geobacillus stearothermophilus 90000.0 10 PMID:16581150;PMID:22561851;PMID:5416895;PMID:5776281 -3.2.1.1 * geobacillus thermodenitrificans 58000.0 1 PMID:16581150;PMID:22561851 -3.2.1.1 * geobacillus thermoleovorans 26000.0 2 PMID:12475615;PMID:18025579;PMID:18443744 -3.2.1.1 * glycine max 100000.0 2 PMID:20655076 -3.2.1.1 * gracilibacillus dipsosauri 80000.0 2 PMID:12081555 -3.2.1.1 * halalkalibacterium halodurans 100000.0 4 PMID:17928706 -3.2.1.1 * haliotis discus discus 54000.0 1 PMID:19135166 -3.2.1.1 * haloarcula japonica 83000.0 2 PMID:23391916 -3.2.1.1 * haloarcula sp. 70000.0 2 PMID:15378403;PMID:942374 -3.2.1.1 * haloferax mediterranei 58000.0 2 PMID:12910390 -3.2.1.1 * halorubrum xinjiangense 60000.0 2 PMID:23695659 -3.2.1.1 * haloterrigena turkmenica 54000.0 1 PMID:17920264;PMID:27377461 -3.2.1.1 * halothermothrix orenii 71000.0 1 PMID:18387632 -3.2.1.1 * heterorhabditis bacteriophora 47000.0 2 PMID:15364283 -3.2.1.1 * homo sapiens 62000.0 11 PMID:11914097;PMID:14678792;PMID:16511271;PMID:4699244;PMID:5134534 -3.2.1.1 * hordeum vulgare 75000.0 4 PMID:11890202;PMID:16403494;PMID:18467868 -3.2.1.1 * humicola stellata 48000.0 1 * -3.2.1.1 * hyphopichia burtonii 51750.0 2 PMID:17151461;PMID:18071262 -3.2.1.1 * klebsiella pneumoniae 67000.0 1 PMID:15583388 -3.2.1.1 * laceyella sacchari 31000.0 1 * -3.2.1.1 * lacticaseibacillus manihotivorans 135000.0 1 PMID:10938420 -3.2.1.1 * lactobacillus amylovorus 127000.0 3 PMID:10919790;PMID:19618275 -3.2.1.1 * lactococcus lactis 121000.0 2 PMID:20890096 -3.2.1.1 * lathyrus oleraceus 45000.0 3 PMID:16667384 -3.2.1.1 * limosilactobacillus fermentum 24000.0 2 * -3.2.1.1 * lipomyces starkeyi 76000.0 3 PMID:15043869 -3.2.1.1 * lysobacter brunescens 49000.0 2 * -3.2.1.1 * malus pumila 51180.0 1 * -3.2.1.1 * meretrix lusoria 100000.0 3 * -3.2.1.1 * micrococcus luteus 56000.0 1 PMID:9438346 -3.2.1.1 * moesziomyces antarcticus 51000.0 2 PMID:3106037 -3.2.1.1 * moneuplotes crassus 53000.0 1 PMID:16850297;PMID:18157528;PMID:23916704 -3.2.1.1 * morimus funereus 33000.0 2 PMID:17942357 -3.2.1.1 * mus musculus 56286.0 2 PMID:11329174 -3.2.1.1 * musa acuminata 46000.0 2 PMID:17032032 -3.2.1.1 * mycothermus thermophilus 49000.0 1 PMID:12743761 -3.2.1.1 * mytilus galloprovincialis 66000.0 1 PMID:16009590 -3.2.1.1 * niallia circulans 76000.0 2 * -3.2.1.1 * nocardiopsis sp. 55000.0 1 PMID:11282629;PMID:17934774;PMID:25152412 -3.2.1.1 * paecilomyces sp. 69000.0 1 * -3.2.1.1 * penicillium brevicompactum 32500.0 1 PMID:20623432 -3.2.1.1 * priestia megaterium 57000.0 1 PMID:20177823 -3.2.1.1 * pseudomonas sp. 96000.0 1 PMID:237562 -3.2.1.1 * pyrococcus furiosus 157000.0 8 PMID:15466542;PMID:8226989;PMID:9195939;PMID:9293008 -3.2.1.1 * pyrococcus sp. 49456.0 2 * -3.2.1.1 * rattus norvegicus 56000.0 2 PMID:3496084;PMID:4621580 -3.2.1.1 * ruminobacter amylophilus 92000.0 1 PMID:14926 -3.2.1.1 * saccharolobus shibatae 61000.0 1 PMID:12549000;PMID:17068753 -3.2.1.1 * saccharolobus solfataricus 240000.0 3 PMID:12511494;PMID:8576067 -3.2.1.1 * saccharomycopsis fibuligera 53000.0 2 PMID:20552260;PMID:9805372 -3.2.1.1 * saitozyma flava 84500.0 5 PMID:14987760;PMID:19570529;PMID:21490699 -3.2.1.1 * schwanniomyces occidentalis 55000.0 1 PMID:18846397;PMID:20131079 -3.2.1.1 * sclerotinia sclerotiorum 43000.0 2 PMID:18852512 -3.2.1.1 * sitophilus zeamais 53700.0 1 PMID:20223242 -3.2.1.1 * sorghum bicolor 47000.0 1 PMID:19278621 -3.2.1.1 * streptomyces fragilis 51000.0 1 PMID:28955647 -3.2.1.1 * streptomyces gulbargensis 57900.0 2 PMID:18846397;PMID:20131079 -3.2.1.1 * streptomyces megasporus 97000.0 1 PMID:10650713 -3.2.1.1 * streptomyces venezuelae 59000.0 1 PMID:3266752 -3.2.1.1 * struthio camelus 52000.0 1 PMID:23916704 -3.2.1.1 * sulfolobus acidocaldarius 435000.0 2 PMID:26104674 -3.2.1.1 * sus scrofa 63000.0 4 PMID:19807164 -3.2.1.1 * tenebrio molitor 68000.0 1 PMID:15378403;PMID:942374 -3.2.1.1 * tepidimonas fonticaldi 48138.0 2 PMID:30928371 -3.2.1.1 * thermoactinomyces sp. 47800.0 1 * -3.2.1.1 * thermobifida fusca 65000.0 1 PMID:20039188;PMID:20495998 -3.2.1.1 * thermococcus hydrothermalis 53600.0 2 PMID:10779714 -3.2.1.1 * thermococcus onnurineus 51948.0 1 PMID:18051591 -3.2.1.1 * thermococcus sp. 51400.0 1 PMID:18587570 -3.2.1.1 * thermomonospora curvata 62000.0 1 PMID:21612 -3.2.1.1 * thermomyces dupontii 59200.0 1 PMID:30703426 -3.2.1.1 * thermomyces lanuginosus 72000.0 3 PMID:20108054 -3.2.1.1 * thermotoga maritima 241000.0 5 PMID:16517673;PMID:19585523 -3.2.1.1 * thermotoga neapolitana 50120.0 2 PMID:19834705 -3.2.1.1 * thermotoga petrophila 62720.0 1 PMID:28648523 -3.2.1.1 * trichoderma pseudokoningii 30000.0 1 PMID:29902965 -3.2.1.1 * tulipa gesneriana 51000.0 2 PMID:3106037 -3.2.1.1 * vibrio sp. 52480.0 1 * -3.2.1.1 * vigna angularis 47000.0 2 PMID:12475615;PMID:12834286 -3.2.1.1 * vigna radiata 46000.0 1 PMID:17524440 -3.2.1.10 * anoxybacillus gonensis 64000.0 2 PMID:37378888 -3.2.1.10 * bacillus cereus 66000.0 2 PMID:2346949 -3.2.1.10 * bacillus flavocaldarius 62000.0 1 * -3.2.1.10 * bacillus pseudomycoides 66000.0 1 * -3.2.1.10 * bacillus sp. f5 63000.0 3 PMID:2346949 -3.2.1.10 * bacillus sp. sam1606 68900.0 1 * -3.2.1.10 * bacillus subtilis 69100.0 2 * -3.2.1.10 * bacillus thermoamyloliquefaciens kp1071 62000.0 2 PMID:2346949 -3.2.1.10 * bifidobacterium adolescentis 72138.0 3 PMID:12658515 -3.2.1.10 * bifidobacterium breve 70000.0 4 PMID:19114534 -3.2.1.10 * cronobacter sakazakii 63600.0 1 * -3.2.1.10 * erwinia rhapontici 63000.0 1 * -3.2.1.10 * exiguobacterium artemiae 66000.0 1 PMID:34439895 -3.2.1.10 * heyndrickxia coagulans 62000.0 2 * -3.2.1.10 * homo sapiens 150000.0 4 PMID:1692546;PMID:20356844;PMID:8924896 -3.2.1.10 * hordeum vulgare 102000.0 1 * -3.2.1.10 * lactiplantibacillus plantarum 68000.0 1 * -3.2.1.10 * necturus sp. 200000.0 1 PMID:11208720 -3.2.1.10 * parageobacillus thermoglucosidasius 66500.0 3 PMID:11834128 -3.2.1.10 * saccharomyces cerevisiae 68700.0 5 PMID:6060462 -3.2.1.10 * sulfolobus acidocaldarius 914000.0 3 PMID:23396915 -3.2.1.10 * suncus murinus 115000.0 2 PMID:11341943 -3.2.1.10 * sus scrofa 260000.0 3 PMID:7002920 -3.2.1.10 * thermoanaerobium sp. 33000.0 1 PMID:3214428 -3.2.1.10 * thermomyces lanuginosus 68000.0 1 * -3.2.1.10 * zalophus californianus 245000.0 1 PMID:6715326 -3.2.1.100 * aeromonas hydrophila 64000.0 1 PMID:7096283 -3.2.1.100 * xanthomonas citri 99480.0 1 PMID:29997257 -3.2.1.101 * niallia circulans 131000.0 4 PMID:11055417;PMID:811665 -3.2.1.102 * clostridium perfringens 88000.0 1 PMID:19630404 -3.2.1.103 * bacteroides fragilis 30000.0 1 PMID:6783650;PMID:6808310 -3.2.1.103 * citrobacter freundii 28000.0 1 PMID:6769923;PMID:6808309 -3.2.1.103 * sphingobacterium multivorum 43000.0 3 PMID:6783650;PMID:6808310;PMID:9831650 -3.2.1.104 * cryptococcus neoformans 120000.0 1 PMID:25361768 -3.2.1.104 * saccharomyces cerevisiae 138000.0 1 PMID:26116408 -3.2.1.104 * sinapis alba 65000.0 1 * -3.2.1.105 * catharanthus roseus 650000.0 8 PMID:10652285;PMID:6768587 -3.2.1.105 * rauvolfia serpentina 450000.0 1 PMID:11985599 -3.2.1.105 * strychnos mellodora 200000.0 4 * -3.2.1.105 * tabernaemontana divaricata 670000.0 5 * -3.2.1.106 * bos taurus 350000.0 8 PMID:2942110;PMID:3322267;PMID:6235111 -3.2.1.106 * candida albicans 50000.0 2 PMID:20358285 -3.2.1.106 * cricetulus griseus 110000.0 1 PMID:18538603 -3.2.1.106 * escherichia coli 85900.0 1 PMID:15213393 -3.2.1.106 * homo sapiens 95000.0 4 PMID:10580131;PMID:7635146;PMID:8786151 -3.2.1.106 * rattus norvegicus 85000.0 1 PMID:1885588;PMID:2673780 -3.2.1.106 * saccharomyces cerevisiae 107000.0 8 PMID:11971867;PMID:14680956;PMID:17458696;PMID:8576053;PMID:9363442;PMID:9878780 -3.2.1.106 * sus scrofa 95000.0 3 PMID:1885588;PMID:2673780;PMID:7635146 -3.2.1.106 * thermus thermophilus 125400.0 2 PMID:25712767 -3.2.1.106 * vigna radiata 316000.0 1 PMID:3521492 -3.2.1.107 * gallus gallus 75000.0 2 PMID:385589 -3.2.1.107 * rattus norvegicus 85000.0 1 PMID:7460918 -3.2.1.108 * homo sapiens 320000.0 9 PMID:17506819;PMID:21763294;PMID:6786877;PMID:6814489 -3.2.1.108 * rattus norvegicus 220000.0 2 PMID:18273561;PMID:18712286 -3.2.1.108 * sus scrofa 320000.0 2 PMID:6786877;PMID:6814489 -3.2.1.109 * pseudomonas sp. 31000.0 1 * -3.2.1.11 * achaetomiella gracilis 77000.0 4 PMID:15944458 -3.2.1.11 * actinomyces israelii 71000.0 1 PMID:240779;PMID:4622623;PMID:4755424 -3.2.1.11 * arthrobacter sp. 64000.0 1 PMID:24197466 -3.2.1.11 * ascospirella lutea 44000.0 1 PMID:15944458 -3.2.1.11 * aspergillus carneus 71000.0 3 PMID:15944458;PMID:240779;PMID:4622623;PMID:4755424 -3.2.1.11 * bacillus licheniformis 158000.0 1 PMID:25881960 -3.2.1.11 * chaetomium erraticum 120000.0 2 * -3.2.1.11 * cytophaga sp. 60000.0 1 * -3.2.1.11 * flavobacterium sp. 114000.0 1 PMID:15944458 -3.2.1.11 * flavobacterium sp. m-73 14000.0 1 * -3.2.1.11 * fusarium sp. 69000.0 1 PMID:9501522 -3.2.1.11 * fusarium verticillioides 39000.0 1 PMID:953 -3.2.1.11 * hoylesella oralis 44000.0 1 PMID:15944458 -3.2.1.11 * lipomyces starkeyi 100000.0 15 PMID:15944458;PMID:17558545;PMID:18082420;PMID:19307767;PMID:20075611;PMID:2753042 -3.2.1.11 * paenibacillus illinoisensis 110000.0 6 PMID:14581071;PMID:15944458 -3.2.1.11 * paenibacillus sp. 120000.0 6 PMID:15281927;PMID:15486706;PMID:15645216 -3.2.1.11 * penicillium chrysogenum 55800.0 2 PMID:15944458 -3.2.1.11 * penicillium sp. 62000.0 1 PMID:17558545 -3.2.1.11 * pseudarthrobacter oxydans 240000.0 4 PMID:24721052 -3.2.1.11 * pseudomonas sp. 114000.0 1 PMID:15944458 -3.2.1.11 * pseudothermotoga lettingae 64000.0 1 PMID:19597811 -3.2.1.11 * purpureocillium lilacinum 26500.0 1 * -3.2.1.11 * sporothrix schenckii 79000.0 1 PMID:9683645 -3.2.1.11 * streptococcus criceti 200000.0 12 PMID:17704634 -3.2.1.11 * streptococcus mutans 97000.0 5 PMID:12030973;PMID:17704634;PMID:21479716 -3.2.1.11 * streptococcus mutans ingbritt 78000.0 1 PMID:1461154;PMID:8551969 -3.2.1.11 * streptococcus ratti 135000.0 2 PMID:15031528 -3.2.1.11 * streptococcus salivarius 190000.0 2 PMID:17704634 -3.2.1.11 * streptococcus sobrinus 260000.0 10 PMID:15944458;PMID:17704634;PMID:3546141;PMID:7526133;PMID:8021165 -3.2.1.11 * streptomyces sp. 130000.0 1 PMID:22277209 -3.2.1.11 * talaromyces aculeatus 80000.0 4 PMID:18264680;PMID:18307270 -3.2.1.11 * talaromyces funiculosus 44000.0 3 PMID:15944458;PMID:4731965 -3.2.1.11 * talaromyces minioluteus 67000.0 2 PMID:12839491;PMID:12962629 -3.2.1.11 * thermoanaerobacter pseudethanolicus 70000.0 1 PMID:22561857 -3.2.1.11 * thermoanaerobacter sp. 140000.0 1 PMID:15944458 -3.2.1.111 * bifidobacterium bifidum 350000.0 2 PMID:19520709 -3.2.1.111 * prunus dulcis 73000.0 1 PMID:7085666 -3.2.1.111 * uncultured bacterium 56200.0 2 PMID:35137077 -3.2.1.113 * arabidopsis thaliana 60000.0 1 PMID:19914916 -3.2.1.113 * aspergillus oryzae 67000.0 1 PMID:16495665 -3.2.1.113 * aspergillus phoenicis 64000.0 1 * -3.2.1.113 * bacillus sp. (in: firmicutes) 380000.0 2 PMID:8149382 -3.2.1.113 * bos taurus 56000.0 1 PMID:2941301 -3.2.1.113 * coccidioides posadasii 56920.0 1 PMID:17363438 -3.2.1.113 * homo sapiens 71000.0 3 PMID:21450520;PMID:8223597 -3.2.1.113 * rattus norvegicus 230000.0 1 PMID:2560126 -3.2.1.113 * saccharomyces cerevisiae 66000.0 1 PMID:1822240 -3.2.1.113 * spodoptera frugiperda 63000.0 1 PMID:7873528 -3.2.1.113 * sus scrofa 65000.0 2 PMID:1521536;PMID:2604721 -3.2.1.113 * trypanosoma cruzi 160000.0 2 PMID:10207175 -3.2.1.114 * aspergillus fumigatus 124000.0 1 PMID:19240271 -3.2.1.114 * aspergillus phoenicis 110000.0 4 PMID:15721331 -3.2.1.114 * capra hircus 130500.0 1 PMID:26306528 -3.2.1.114 * drosophila melanogaster 127000.0 1 PMID:7890162 -3.2.1.114 * ginkgo biloba 340000.0 3 PMID:15618626;PMID:15973042 -3.2.1.114 * homo sapiens 468000.0 2 PMID:17681998 -3.2.1.114 * mus musculus 131000.0 2 PMID:1757461;PMID:3733740;PMID:3922977 -3.2.1.114 * oryctolagus cuniculus 52000.0 3 PMID:2917980 -3.2.1.114 * rattus norvegicus 295000.0 10 PMID:1885615;PMID:2246269;PMID:3733740;PMID:3922977;PMID:863880 -3.2.1.114 * spodoptera frugiperda 240000.0 3 PMID:11279010;PMID:9210421 -3.2.1.114 * vigna radiata 128000.0 2 PMID:2139344;PMID:2560127 -3.2.1.114 * vigna radiata var. radiata 460000.0 2 PMID:4051507 -3.2.1.115 * flavobacterium sp. 125000.0 2 PMID:7407800 -3.2.1.115 * microbacterium dextranolyticum 122000.0 1 PMID:37033117 -3.2.1.116 * kitasatospora sp. mk-1785 57000.0 1 PMID:25620369 -3.2.1.116 * microbacterium imperiale 50000.0 3 PMID:24345719 -3.2.1.116 * microbulbifer thermotolerans 80000.0 1 PMID:25381490 -3.2.1.116 * natronococcus sp. 76000.0 2 PMID:1592801 -3.2.1.116 * thermobifida fusca 64000.0 2 * -3.2.1.117 * penicillium aurantiogriseum 247000.0 4 PMID:10380623;PMID:9446681 -3.2.1.117 * prunus serotina 62000.0 5 PMID:12232341;PMID:16652959;PMID:7480328 -3.2.1.118 * penicillium aurantiogriseum 66400.0 2 PMID:9446681 -3.2.1.118 * prunus domestica 60000.0 1 PMID:12232058 -3.2.1.118 * prunus dulcis 150000.0 2 PMID:22353576 -3.2.1.118 * prunus serotina 140000.0 8 PMID:12114579;PMID:12232341;PMID:16652959;PMID:3109321 -3.2.1.119 * davallia trichomanoides 73000.0 1 PMID:16665903 -3.2.1.119 * vicia sativa subsp. nigra 56000.0 2 PMID:17548373 -3.2.1.120 * aspergillus aculeatus 34000.0 3 PMID:9884411 -3.2.1.120 * aspergillus oryzae 230000.0 2 PMID:4019436 -3.2.1.120 * lathyrus oleraceus 77000.0 2 PMID:12223734 -3.2.1.120 * oerskovia sp. 105000.0 1 * -3.2.1.120 * thermobifida fusca 79480.0 2 PMID:12846842 -3.2.1.120 * vigna angularis 32000.0 1 * -3.2.1.122 * bacillus subtilis 50513.0 1 PMID:10329789 -3.2.1.122 * clostridium acetobutylicum 200000.0 8 PMID:14570887 -3.2.1.122 * escherichia coli 49386.0 1 PMID:11882720 -3.2.1.122 * fusobacterium mortiferum 50000.0 5 PMID:11882720;PMID:16636060;PMID:7730284;PMID:9209025 -3.2.1.122 * klebsiella pneumoniae 100000.0 5 PMID:11473129;PMID:11882720;PMID:16636060;PMID:7730284;PMID:9209025 -3.2.1.123 * corynebacterium sp. 450000.0 2 PMID:1315273 -3.2.1.123 * cyanea nozakii 51000.0 1 PMID:10882727 -3.2.1.123 * hydra vulgaris 59680.0 3 PMID:15320336 -3.2.1.123 * prescottella equi 55000.0 3 PMID:17244618;PMID:22798689 -3.2.1.123 * rhodococcus sp. (in: high g+c gram-positive bacteria) 58900.0 6 PMID:10381348;PMID:10876169;PMID:2722847 -3.2.1.125 * rauvolfia serpentina 66600.0 7 PMID:10234858;PMID:10975500 -3.2.1.126 * agrobacterium tumefaciens 98000.0 2 PMID:9630531 -3.2.1.126 * cicer arietinum 110000.0 3 PMID:25181 -3.2.1.126 * picea abies 58570.0 2 PMID:27355 -3.2.1.126 * pinus banksiana 110000.0 2 PMID:7765617 -3.2.1.126 * pinus contorta 60000.0 2 PMID:7724669 -3.2.1.127 * aspergillus niger 180000.0 1 PMID:2423086 -3.2.1.127 * saccharolobus solfataricus 508000.0 3 PMID:15207718 -3.2.1.127 * tannerella forsythia 51000.0 1 PMID:25831954 -3.2.1.128 * aspergillus niger 150000.0 1 * -3.2.1.129 * bacteriophage pk1e 74000.0 1 PMID:7565105;PMID:7626018 -3.2.1.129 * enterobacteria phage k1a 89000.0 2 PMID:17394421 -3.2.1.129 * escherichia phage k1f 328000.0 5 PMID:12556457;PMID:20124697;PMID:3546309 -3.2.1.129 * phage e 208000.0 3 PMID:3894684 -3.2.1.129 * vectrevirus k1e 76000.0 2 PMID:11994155;PMID:7565105;PMID:7626018 -3.2.1.130 * bos taurus 50000.0 1 PMID:22641772 -3.2.1.130 * cricetulus griseus 53220.0 2 PMID:17593322 -3.2.1.130 * homo sapiens 55000.0 1 PMID:15677381 -3.2.1.130 * rattus norvegicus 560000.0 9 PMID:11201607;PMID:15677381;PMID:17593322;PMID:2407194;PMID:8106437;PMID:9361017 -3.2.1.131 * amphibacillus xylanus 110000.0 2 PMID:28648176 -3.2.1.131 * aspergillus fumigatus 100000.0 2 PMID:23719223 -3.2.1.131 * bacteroides ovatus 199000.0 2 PMID:24214982 -3.2.1.131 * caldicellulosiruptor acetigenus 163700.0 3 PMID:25184498 -3.2.1.131 * cellvibrio japonicus 150000.0 2 PMID:11358519;PMID:11937059 -3.2.1.131 * geobacillus stearothermophilus 150000.0 2 PMID:10089319;PMID:11358519;PMID:11937059 -3.2.1.131 * paenibacillus curdlanolyticus 77300.0 1 PMID:25765307 -3.2.1.131 * phlebia radiata 110000.0 1 PMID:16109636 -3.2.1.131 * pseudothermotoga thermarum 70000.0 1 * -3.2.1.131 * saccharophagus degradans 70800.0 1 PMID:27129264 -3.2.1.131 * scheffersomyces stipitis cbs 6054 120000.0 1 PMID:19344716 -3.2.1.131 * schizophyllum commune 125000.0 2 PMID:10725538;PMID:21442271 -3.2.1.131 * uncultured bacterium 84500.0 1 PMID:22526332 -3.2.1.132 * acinetobacter calcoaceticus 66000.0 2 PMID:24360467 -3.2.1.132 * acinetobacter sp. 35400.0 1 PMID:12728987 -3.2.1.132 * aeromonas sp. 70000.0 1 * -3.2.1.132 * amycolatopsis orientalis 26000.0 2 PMID:15270720 -3.2.1.132 * amycolatopsis sp. 27000.0 1 * -3.2.1.132 * amycolatopsis sp. cso-2 30000.0 2 PMID:19236484 -3.2.1.132 * amylomyces rouxii 79000.0 3 * -3.2.1.132 * ananas comosus 31400.0 2 PMID:12137495 -3.2.1.132 * aspergillus fumigatus 111200.0 7 PMID:14723337;PMID:22160328;PMID:22878198;PMID:24360467 -3.2.1.132 * aspergillus oryzae 135000.0 2 PMID:11055393 -3.2.1.132 * aspergillus sp. w-2 25148.0 1 PMID:26277746 -3.2.1.132 * bacillus cereus 81000.0 8 PMID:10568796;PMID:15294781;PMID:16756348;PMID:19458918;PMID:22647542;PMID:22985087;PMID:24360467;PMID:24444885;PMID:26433174 -3.2.1.132 * bacillus licheniformis 75000.0 3 PMID:16757796;PMID:69 -3.2.1.132 * bacillus sp. (in: firmicutes) 52000.0 15 PMID:10568796;PMID:14519970;PMID:15294781;PMID:15500976;PMID:16756348;PMID:19342008;PMID:69 -3.2.1.132 * bacillus sp. dau101 31420.0 2 PMID:16645821 -3.2.1.132 * bacillus sp. ts 47000.0 1 PMID:25637506 -3.2.1.132 * bacillus subtilis 53000.0 5 PMID:22031025;PMID:34409950 -3.2.1.132 * bacillus thuringiensis 59000.0 2 PMID:15114873;PMID:21512238 -3.2.1.132 * bambusa oldhamii 24500.0 4 PMID:22166086;PMID:24360467 -3.2.1.132 * burkholderia gladioli 28000.0 1 PMID:11030572 -3.2.1.132 * campanula rotundifolia 19000.0 1 * -3.2.1.132 * chaetomium globosum 47000.0 1 PMID:22985087 -3.2.1.132 * citrus sinensis 30500.0 1 * -3.2.1.132 * cucumis sativus 20000.0 4 * -3.2.1.132 * enterobacter sp. 50000.0 1 * -3.2.1.132 * ficus pumila var. awkeotsang 20500.0 1 PMID:26938062 -3.2.1.132 * ficus sp. 16600.0 1 PMID:16159189 -3.2.1.132 * fusarium solani 36000.0 1 * -3.2.1.132 * gongronella sp. 90000.0 3 PMID:17983432;PMID:18722595;PMID:22160328;PMID:24360467 -3.2.1.132 * gynuella sunshinyii 29700.0 3 PMID:29502814;PMID:30621320 -3.2.1.132 * janthinobacterium sp. 33000.0 1 PMID:24360467 -3.2.1.132 * janthinobacterium sp. 4239 33000.0 2 PMID:20096097 -3.2.1.132 * lathyrus oleraceus 23000.0 2 * -3.2.1.132 * lysobacter sp. 41241.0 2 PMID:17031054 -3.2.1.132 * macrotermes estherae 40000.0 3 PMID:12568570 -3.2.1.132 * metarhizium anisopliae 45000.0 1 * -3.2.1.132 * microbacterium sp. 81000.0 3 PMID:16820974;PMID:17563859 -3.2.1.132 * mucor circinelloides 42000.0 1 * -3.2.1.132 * myxobacter sp. al-1 28900.0 1 * -3.2.1.132 * niallia circulans 32000.0 5 PMID:10521473 -3.2.1.132 * onoclea sensibilis 21000.0 2 * -3.2.1.132 * paenibacillus dendritiformis 31000.0 1 PMID:29687713 -3.2.1.132 * paenibacillus fukuinensis 85610.0 1 PMID:20068354 -3.2.1.132 * paenibacillus mucilaginosus 59000.0 1 PMID:30974812 -3.2.1.132 * paenibacillus sp. 41800.0 3 PMID:23076590;PMID:24360467 -3.2.1.132 * penicillium chrysogenum 40000.0 3 PMID:20652693 -3.2.1.132 * penicillium sp. 43000.0 1 PMID:24444885 -3.2.1.132 * priestia megaterium 43000.0 3 PMID:16348170 -3.2.1.132 * pseudoalteromonas sp. sy39 28000.0 1 PMID:29502814;PMID:30621320 -3.2.1.132 * pseudomonas sp. 35000.0 2 PMID:18378219;PMID:3147359 -3.2.1.132 * pseudomonas sp. a-01 28000.0 2 PMID:18685218 -3.2.1.132 * purpureocillium lilacinum 25500.0 2 PMID:15270720 -3.2.1.132 * renibacterium sp. qd1 26000.0 1 PMID:29155203 -3.2.1.132 * rhodotorula toruloides 100000.0 1 * -3.2.1.132 * serratia marcescens 36000.0 6 PMID:18420186;PMID:24360467 -3.2.1.132 * setaria italica 22000.0 2 * -3.2.1.132 * solanum lycopersicum 20000.0 1 * -3.2.1.132 * solanum melongena 23000.0 3 * -3.2.1.132 * streptomyces griseus 39000.0 4 PMID:20100524;PMID:3147359 -3.2.1.132 * streptomyces roseolus 41000.0 1 PMID:22647542;PMID:24360467 -3.2.1.132 * streptomyces sp. 29500.0 4 PMID:371 -3.2.1.132 * streptomyces zaomyceticus 95000.0 1 * -3.2.1.132 * sus scrofa 43700.0 4 PMID:12568570 -3.2.1.132 * talaromyces islandicus 30000.0 1 * -3.2.1.132 * thuja occidentalis 22000.0 2 * -3.2.1.132 * trichoderma viride 66000.0 2 * -3.2.1.132 * triticum aestivum 19000.0 2 * -3.2.1.132 * uncultured bacterium 31000.0 1 * -3.2.1.133 * aspergillus niger 53000.0 1 * -3.2.1.133 * bacillus sp. (in: firmicutes) 135000.0 3 PMID:18049800;PMID:20855205;PMID:23771845 -3.2.1.133 * bacillus subtilis 109000.0 4 PMID:10825545 -3.2.1.133 * geobacillus sp. 65000.0 1 PMID:23639697 -3.2.1.133 * geobacillus sp. sk70 135000.0 1 * -3.2.1.133 * geobacillus stearothermophilus 70000.0 3 PMID:22868150;PMID:25038884;PMID:26597712 -3.2.1.133 * geobacillus thermoleovorans 725000.0 3 PMID:24069213 -3.2.1.133 * lactobacillus gasseri 211000.0 4 PMID:16198511;PMID:18062231 -3.2.1.133 * pyrococcus sp. 260000.0 3 PMID:23884203 -3.2.1.133 * saccharococcus caldoxylosilyticus 70030.0 1 * -3.2.1.133 * shouchella lehensis 104700.0 2 PMID:25221964 -3.2.1.133 * thermococcus sp. 70000.0 2 PMID:24835094 -3.2.1.133 * thermofilum pendens 74252.0 2 PMID:19707756 -3.2.1.133 * thermoplasma volcanium 72090.0 2 PMID:17468058 -3.2.1.133 * thermotoga neapolitana 50000.0 1 PMID:23519419 -3.2.1.133 * thermus sp. 112000.0 3 PMID:11714271;PMID:17587692 -3.2.1.133 * trigonella foenum-graecum 68000.0 1 * -3.2.1.135 * alicyclobacillus acidocaldarius 66000.0 1 PMID:10825529;PMID:15239382 -3.2.1.135 * bacillus sp. ksm-1876 68000.0 1 PMID:10825529 -3.2.1.135 * bacteroides thetaiotaomicron 70000.0 3 PMID:15239382;PMID:1708385 -3.2.1.135 * bifidobacterium breve 175000.0 1 PMID:18223106 -3.2.1.135 * geobacillus stearothermophilus 140000.0 6 PMID:11834127;PMID:15239382;PMID:3127377 -3.2.1.135 * klebsiella pneumoniae 66000.0 1 PMID:10825529;PMID:15239382 -3.2.1.135 * nesterenkonia halobia 53000.0 1 PMID:11318036 -3.2.1.135 * paenibacillus polymyxa 58000.0 1 * -3.2.1.135 * thermoactinomyces vulgaris 65000.0 1 PMID:15239382 -3.2.1.135 * thermoanaerobacter ethanolicus 107818.0 3 PMID:18500431 -3.2.1.135 * uncultured microorganism 66000.0 1 PMID:18540099 -3.2.1.136 * acetivibrio thermocellus 61200.0 4 PMID:27841749 -3.2.1.136 * bacillus subtilis 45000.0 1 PMID:16666240 -3.2.1.136 * cellulomonas flavigena 49000.0 1 PMID:18379842 -3.2.1.136 * thermomyces lanuginosus 26300.0 1 PMID:9648252 -3.2.1.137 * cellulomonas sp. 450000.0 1 * -3.2.1.139 * agaricus bisporus 160000.0 1 * -3.2.1.139 * aspergillus fumigatus 91730.0 1 PMID:23719223 -3.2.1.139 * aspergillus niger 150000.0 4 PMID:12169619;PMID:15784980 -3.2.1.139 * aureobasidium pullulans 91000.0 1 * -3.2.1.139 * bacteroides ovatus 199000.0 2 PMID:24214982 -3.2.1.139 * bacteroides sp. 80000.0 1 PMID:9300126 -3.2.1.139 * cellvibrio japonicus 150000.0 1 PMID:12169619 -3.2.1.139 * geobacillus stearothermophilus 161000.0 4 PMID:11210113;PMID:11358519 -3.2.1.139 * helix pomatia 180000.0 2 PMID:8901117 -3.2.1.139 * paenibacillus curdlanolyticus 77300.0 1 PMID:25765307 -3.2.1.139 * paenibacillus sp. 115000.0 2 * -3.2.1.139 * piromyces communis 300000.0 1 PMID:7576556 -3.2.1.139 * rasamsonia emersonii 150000.0 3 PMID:27195020 -3.2.1.139 * saccharophagus degradans 70800.0 1 PMID:27129264 -3.2.1.139 * scheffersomyces stipitis 120000.0 1 PMID:19344716 -3.2.1.139 * streptomyces pristinaespiralis 114000.0 2 PMID:21206027 -3.2.1.139 * thermoanaerobacterium saccharolyticum 130000.0 4 PMID:16534958;PMID:2802623;PMID:7496513 -3.2.1.139 * thermoascus aurantiacus 118000.0 2 PMID:2802623;PMID:7496513 -3.2.1.139 * thermoclostridium stercorarium 124000.0 3 PMID:7496513 -3.2.1.139 * trichoderma reesei 100000.0 2 * -3.2.1.14 * aeromonas hydrophila 115000.0 3 PMID:17031053 -3.2.1.14 * aeromonas schubertii 61202.0 3 PMID:19197977 -3.2.1.14 * aeromonas sp. 120000.0 6 PMID:8541660 -3.2.1.14 * alteromonas sp. 70000.0 2 PMID:10441726;PMID:1464065;PMID:17629497;PMID:9464381 -3.2.1.14 * amycolatopsis orientalis 33000.0 2 * -3.2.1.14 * amylomyces rouxii 30700.0 2 PMID:2778431 -3.2.1.14 * ananas comosus 31400.0 4 PMID:12137495 -3.2.1.14 * annona cherimola 14500.0 3 PMID:20576315 -3.2.1.14 * apriona germarii 46000.0 1 PMID:11454002 -3.2.1.14 * arabidopsis thaliana 32000.0 1 PMID:10627034;PMID:11709578;PMID:11911477;PMID:12784603;PMID:16668004;PMID:18359848 -3.2.1.14 * aspergillus fumigatus 46000.0 1 PMID:11454002 -3.2.1.14 * aspergillus sp. 51000.0 2 PMID:17630125 -3.2.1.14 * astragalus membranaceus 36900.0 2 * -3.2.1.14 * autographa californica multiple nucleopolyhedrovirus 65000.0 1 PMID:21897030 -3.2.1.14 * avena sativa 34000.0 1 PMID:12469313;PMID:18626709;PMID:19224400;PMID:19342775 -3.2.1.14 * bacillus cereus 74500.0 6 PMID:12452952;PMID:12882563;PMID:16946479;PMID:18843519;PMID:19420688;PMID:20622499;PMID:24342954;PMID:9783424 -3.2.1.14 * bacillus licheniformis 72000.0 7 PMID:19190863;PMID:19756579;PMID:20133129;PMID:22037312 -3.2.1.14 * bacillus sp. (in: firmicutes) 808000.0 11 PMID:10792540;PMID:12074700;PMID:12452952;PMID:12882563;PMID:14634152;PMID:18843519;PMID:9726888 -3.2.1.14 * bacillus sp. sc081 65878.0 2 PMID:21429298 -3.2.1.14 * bacillus subtilis 85000.0 3 * -3.2.1.14 * bacillus thuringiensis 74500.0 5 PMID:17873409;PMID:18080218 -3.2.1.14 * bambusa oldhamii 35700.0 2 PMID:18998701 -3.2.1.14 * benincasa hispida 29000.0 1 PMID:11330660 -3.2.1.14 * bombyx mori 88000.0 3 PMID:16428840;PMID:9443376 -3.2.1.14 * bos taurus 47000.0 1 PMID:41711 -3.2.1.14 * brassica oleracea 41000.0 1 PMID:8896765 -3.2.1.14 * brevibacillus formosus 37600.0 1 PMID:24473902 -3.2.1.14 * bromus inermis 32000.0 1 PMID:10627034;PMID:11709578;PMID:11911477;PMID:12784603;PMID:16668004;PMID:18359848 -3.2.1.14 * burkholderia cepacia 34000.0 1 PMID:12469313;PMID:18626709;PMID:19224400;PMID:19342775 -3.2.1.14 * capra hircus 60000.0 1 PMID:4211869 -3.2.1.14 * carica papaya 26733.0 4 PMID:17115118;PMID:17263465;PMID:19665502 -3.2.1.14 * cellulosimicrobium cellulans 61000.0 1 PMID:24031407 -3.2.1.14 * chelonus sp. 52000.0 1 PMID:19267677;PMID:21945415;PMID:8063715 -3.2.1.14 * chitiniphilus shinanonensis 80800.0 3 PMID:22451394 -3.2.1.14 * chondrus verrucosus 25500.0 2 PMID:19060408 -3.2.1.14 * cicer arietinum 32000.0 2 PMID:7763357 -3.2.1.14 * citrobacter freundii 64000.0 1 PMID:24065288 -3.2.1.14 * citrus sinensis 28000.0 6 PMID:8931350 -3.2.1.14 * clonostachys rosea 44000.0 1 PMID:19342787 -3.2.1.14 * clostridium paraputrificum 74651.0 1 PMID:17091272 -3.2.1.14 * clostridium sp. e-16 98000.0 2 PMID:16869903 -3.2.1.14 * cucurbita maxima 29000.0 1 * -3.2.1.14 * cupiennius salei 48000.0 1 PMID:7370275 -3.2.1.14 * cycas revoluta 38000.0 1 PMID:19696236 -3.2.1.14 * daucus carota 34000.0 7 PMID:8790295 -3.2.1.14 * dioscorea oppositifolia 33500.0 1 * -3.2.1.14 * dioscorea polystachya 32000.0 1 PMID:25036674 -3.2.1.14 * ephemerocybe congregata 68000.0 1 PMID:23625219 -3.2.1.14 * ficus pumila var. awkeotsang 30000.0 1 PMID:12074700;PMID:14634152 -3.2.1.14 * francisella tularensis subsp. novicida 120000.0 3 PMID:21531796 -3.2.1.14 * fusarium chlamydosporum 40000.0 1 PMID:20622499;PMID:24342954;PMID:9783424 -3.2.1.14 * gallus gallus 57800.0 2 * -3.2.1.14 * gemmabryum coronatum 25000.0 2 PMID:21367878 -3.2.1.14 * gladiolus x gandavensis 30000.0 1 PMID:9438997 -3.2.1.14 * glycine max 32000.0 1 PMID:10627034;PMID:11709578;PMID:11911477;PMID:12784603;PMID:16668004;PMID:18359848 -3.2.1.14 * halobacterium salinarum 66500.0 1 PMID:23893326 -3.2.1.14 * hexagrammos otakii 62000.0 3 PMID:16636466 -3.2.1.14 * homo sapiens 50000.0 2 PMID:7836450 -3.2.1.14 * hordeum vulgare 34000.0 4 PMID:12469313;PMID:17263465;PMID:18626709;PMID:1899089;PMID:19224400;PMID:19342775;PMID:19665502 -3.2.1.14 * ipomoea carnea 30060.0 1 * -3.2.1.14 * isoptericola jiangsuensis 60000.0 2 PMID:20922373 -3.2.1.14 * laceyella putida 75000.0 2 PMID:24737059 -3.2.1.14 * lathyrus oleraceus 39000.0 3 PMID:16666142 -3.2.1.14 * leucaena leucocephala 32000.0 1 PMID:10627034;PMID:11709578;PMID:11911477;PMID:12784603;PMID:16668004;PMID:18359848 -3.2.1.14 * limonium bicolor 31700.0 2 PMID:19685157 -3.2.1.14 * macaca fascicularis 52200.0 1 PMID:20036323 -3.2.1.14 * malbranchea chrysosporioidea 100000.0 1 * -3.2.1.14 * manduca sexta 85000.0 4 PMID:12770581 -3.2.1.14 * massilia timonae 64000.0 3 PMID:19962135 -3.2.1.14 * metarhizium anisopliae 43500.0 3 PMID:14735222;PMID:24263941;PMID:438221 -3.2.1.14 * microbispora sp. 35000.0 1 PMID:12452952;PMID:12882563;PMID:18843519 -3.2.1.14 * monascus purpureus 81000.0 1 PMID:11929279 -3.2.1.14 * moritella marina 60788.0 2 PMID:18368288 -3.2.1.14 * mus musculus 78000.0 1 PMID:19076793 -3.2.1.14 * nepenthes alata 29000.0 1 PMID:21930651 -3.2.1.14 * neurospora crassa 20600.0 1 PMID:2976112 -3.2.1.14 * niallia circulans 66000.0 2 PMID:10441726;PMID:17629497;PMID:9464381 -3.2.1.14 * nicotiana tabacum 34000.0 3 PMID:11414619;PMID:17178105 -3.2.1.14 * nocardiopsis prasina 31500.0 1 PMID:16010517 -3.2.1.14 * nocardiopsis sp. 33000.0 1 PMID:15502313 -3.2.1.14 * oreochromis niloticus 75000.0 1 PMID:17126584 -3.2.1.14 * oryza sativa 33600.0 4 PMID:10627034;PMID:11709578;PMID:11911477;PMID:12784603;PMID:16668004;PMID:18359848;PMID:7765038 -3.2.1.14 * paenibacillus barengoltzii 72300.0 2 PMID:26304445;PMID:27320843 -3.2.1.14 * paenibacillus sp. 150000.0 3 PMID:21049291;PMID:25036959 -3.2.1.14 * paenibacillus thermoaerophilus 48000.0 1 PMID:25304023;PMID:7103511 -3.2.1.14 * panax ginseng 34900.0 1 PMID:20306227 -3.2.1.14 * penaeus japonicus 37000.0 1 * -3.2.1.14 * penaeus vannamei 50000.0 1 PMID:9769251 -3.2.1.14 * penicillium ochrochloron 64000.0 1 PMID:24065288 -3.2.1.14 * penicillium sp. 47000.0 1 PMID:19116167 -3.2.1.14 * pennahia argentata 42000.0 1 PMID:19297695 -3.2.1.14 * petroselinum crispum 38200.0 6 PMID:8477714 -3.2.1.14 * phaseolus lunatus 28600.0 1 PMID:18782228 -3.2.1.14 * phaseolus vulgaris 32500.0 5 PMID:19547968;PMID:24263941;PMID:438221 -3.2.1.14 * phytolacca americana 29000.0 2 PMID:7772831 -3.2.1.14 * piromyces communis 44900.0 2 PMID:9175560;PMID:9625792 -3.2.1.14 * plasmodium gallinaceum 50000.0 1 PMID:9769251 -3.2.1.14 * pochonia chlamydosporia 44000.0 1 * -3.2.1.14 * pseudoalteromonas tunicata 53500.0 1 * -3.2.1.14 * pseudomonas sp. 68000.0 2 PMID:18378219;PMID:20622499;PMID:24342954;PMID:9783424 -3.2.1.14 * pyrococcus furiosus 39700.0 1 PMID:12788706 -3.2.1.14 * rhizomucor miehei 44700.0 1 PMID:26709620 -3.2.1.14 * saccharopolyspora erythraea 30000.0 1 PMID:2732220 -3.2.1.14 * sceloporus consobrinus 54000.0 2 PMID:11290449 -3.2.1.14 * scorpaena scrofa 50103.0 2 PMID:22972353 -3.2.1.14 * secale cereale 34000.0 2 PMID:12469313;PMID:18626709;PMID:19224400;PMID:19342775 -3.2.1.14 * serratia liquefaciens 56000.0 1 * -3.2.1.14 * serratia marcescens 62000.0 7 PMID:16453672;PMID:19267677;PMID:21945415;PMID:22555558;PMID:6762111;PMID:8063715 -3.2.1.14 * solanum lycopersicum 31000.0 2 PMID:18175902 -3.2.1.14 * stenotrophomonas maltophilia 52000.0 1 PMID:19267677;PMID:21945415;PMID:8063715 -3.2.1.14 * stomoxys calcitrans 48000.0 1 PMID:25304023;PMID:7103511 -3.2.1.14 * streptomyces cyaneus 29000.0 4 PMID:18175902;PMID:18603792 -3.2.1.14 * streptomyces fradiae 43000.0 2 PMID:16010517 -3.2.1.14 * streptomyces griseus 32000.0 1 PMID:10627034;PMID:11709578;PMID:11911477;PMID:12784603;PMID:16668004;PMID:18359848 -3.2.1.14 * streptomyces lydicus 37000.0 2 * -3.2.1.14 * streptomyces sp. 70000.0 6 PMID:11309080;PMID:12689517;PMID:5493208;PMID:7549109 -3.2.1.14 * streptomyces sp. da11 34000.0 1 PMID:12469313;PMID:18626709;PMID:19224400;PMID:19342775 -3.2.1.14 * streptomyces venezuelae 66000.0 1 PMID:16972135 -3.2.1.14 * sulfurisphaera tokodaii 130000.0 3 PMID:22154063 -3.2.1.14 * tamarindus indica 34000.0 1 PMID:12469313;PMID:18626709;PMID:19224400;PMID:19342775 -3.2.1.14 * tenebrio molitor 44000.0 2 PMID:17027845 -3.2.1.14 * thermoascus aurantiacus var. levisporus 48400.0 1 PMID:20223653 -3.2.1.14 * thermochaetoides thermophila 47300.0 1 PMID:20223653 -3.2.1.14 * thermococcus chitonophagus 70000.0 1 PMID:12579379 -3.2.1.14 * thermococcus kodakarensis 134259.0 1 PMID:11210511 -3.2.1.14 * trametes cinnabarina 38000.0 1 * -3.2.1.14 * trichoderma atroviride 45000.0 1 PMID:10441726;PMID:17629497;PMID:9464381 -3.2.1.14 * trichoderma harzianum 81000.0 4 PMID:1606968 -3.2.1.14 * trichoderma reesei 46000.0 2 PMID:16341861 -3.2.1.14 * trichoderma viride 46000.0 2 PMID:11454002;PMID:12483557 -3.2.1.14 * triticum aestivum 34000.0 8 PMID:12469313;PMID:18626709;PMID:19224400;PMID:19342775;PMID:24263941;PMID:438221 -3.2.1.14 * verticillium albo-atrum 64000.0 1 PMID:24065288 -3.2.1.14 * vibrio alginolyticus 66000.0 2 * -3.2.1.14 * vibrio harveyi 63770.0 1 PMID:16511189 -3.2.1.14 * vibrio proteolyticus 87396.0 4 PMID:17690022;PMID:18214468 -3.2.1.14 * vibrio sp. 63000.0 2 PMID:18368288 -3.2.1.14 * vitis vinifera 31000.0 1 PMID:24845689 -3.2.1.14 * zea mays 28000.0 1 PMID:24616181 -3.2.1.140 * bifidobacterium bifidum 120000.0 2 PMID:18469123 -3.2.1.140 * bifidobacterium bifidum jcm 1254 120000.0 3 PMID:18469123 -3.2.1.140 * bifidobacterium longum 356000.0 2 PMID:23843461 -3.2.1.140 * streptomyces sp. 60000.0 2 PMID:7689556 -3.2.1.141 * metallosphaera hakonensis 150000.0 2 PMID:18051363;PMID:18852510 -3.2.1.141 * nostoc flagelliforme 75000.0 2 PMID:21876373 -3.2.1.141 * saccharolobus solfataricus 128800.0 8 PMID:16968069;PMID:8987868 -3.2.1.141 * sulfolobus acidocaldarius 59000.0 1 PMID:9063974 -3.2.1.142 * anoxybacillus sp. 80000.0 1 PMID:27000839 -3.2.1.142 * avena sativa 80000.0 1 PMID:1170015 -3.2.1.142 * exiguobacterium acetylicum 100000.0 2 PMID:25273816 -3.2.1.142 * hordeum vulgare 105000.0 5 PMID:10350630;PMID:19733243 -3.2.1.142 * lathyrus oleraceus 180000.0 1 PMID:7190872 -3.2.1.142 * sorghum bicolor 90000.0 1 PMID:975121 -3.2.1.142 * vicia faba 80000.0 1 * -3.2.1.143 * bos taurus 110000.0 7 PMID:14720466;PMID:4831224;PMID:8074279;PMID:9115250 -3.2.1.143 * caenorhabditis elegans 138000.0 3 PMID:17188026 -3.2.1.143 * cavia porcellus 75500.0 4 PMID:2043631;PMID:3941108 -3.2.1.143 * homo sapiens 100000.0 5 PMID:16117724;PMID:16278211;PMID:20884351;PMID:2379504 -3.2.1.143 * mus musculus 39000.0 1 PMID:16278211 -3.2.1.143 * sus scrofa 59000.0 3 PMID:6617643;PMID:8951044 -3.2.1.145 * acetivibrio thermocellus 64400.0 3 PMID:16672498;PMID:17090926;PMID:22960181 -3.2.1.145 * bifidobacterium bifidum 67300.0 1 PMID:27050262 -3.2.1.145 * bifidobacterium longum 106100.0 1 PMID:24837371 -3.2.1.145 * irpex lacteus 51000.0 3 PMID:19809200;PMID:2158993 -3.2.1.145 * raphanus sativus 44981.0 2 PMID:15980190 -3.2.1.145 * sphingomonas sp. 48000.0 1 PMID:21452032 -3.2.1.145 * streptomyces avermitilis 38000.0 1 PMID:16672498;PMID:17090926 -3.2.1.145 * streptomyces sp. 48200.0 3 PMID:22464224 -3.2.1.146 * aspergillus niger 90000.0 2 PMID:11342249 -3.2.1.146 * penicillium fellutanum 150000.0 4 PMID:10573856;PMID:11571168 -3.2.1.146 * trichoderma harzianum 35000.0 1 PMID:1383191 -3.2.1.146 * trypanosoma cruzi 55000.0 1 PMID:12615340 -3.2.1.147 * arabidopsis thaliana 150000.0 8 PMID:22682567;PMID:30939944 -3.2.1.147 * armoracia rusticana 130000.0 4 PMID:24333031;PMID:30939944 -3.2.1.147 * brassica carinata 600000.0 1 PMID:18160132 -3.2.1.147 * brassica juncea 250000.0 3 PMID:38030037 -3.2.1.147 * brassica napus 200000.0 20 PMID:11858716;PMID:18160132;PMID:21778185;PMID:2269297;PMID:30939944;PMID:7766877 -3.2.1.147 * brassica oleracea 350000.0 2 PMID:18160132;PMID:25390544 -3.2.1.147 * brassica oleracea var. italica 157000.0 1 PMID:30939944 -3.2.1.147 * brassica rapa 62000.0 1 * -3.2.1.147 * brevicoryne brassicae 126000.0 4 PMID:11102829;PMID:11179970;PMID:30939944 -3.2.1.147 * carica papaya 70000.0 3 PMID:20883440 -3.2.1.147 * crambe hispanica subsp. abyssinica 470000.0 2 PMID:12696966 -3.2.1.147 * enterobacter cloacae 61000.0 1 * -3.2.1.147 * eutrema japonicum 580000.0 2 PMID:30939944 -3.2.1.147 * lepidium latifolium 160000.0 1 PMID:26527478 -3.2.1.147 * lepidium sativum 130000.0 3 PMID:16666767 -3.2.1.147 * raphanus sativus 120000.0 5 PMID:25130502;PMID:30939944 -3.2.1.147 * sinapis alba 200000.0 5 PMID:18160132;PMID:30939944;PMID:5068825 -3.2.1.147 * sinapis sp. 152000.0 6 * -3.2.1.149 * aspergillus fumigatus 47000.0 1 PMID:12036053 -3.2.1.149 * camellia sinensis 61000.0 10 PMID:12481100;PMID:14579595;PMID:18256510 -3.2.1.149 * penicillium multicolor 50000.0 1 PMID:16556987 -3.2.1.15 * achaetomium sp. xz-8 36900.0 2 PMID:23871048 -3.2.1.15 * agroathelia rolfsii 39500.0 2 * -3.2.1.15 * agrobacterium vitis 58000.0 1 PMID:8979363 -3.2.1.15 * amylomyces rouxii 43100.0 1 * -3.2.1.15 * aspergillus awamori 41000.0 1 PMID:10993164;PMID:4037779 -3.2.1.15 * aspergillus foetidus 34000.0 1 * -3.2.1.15 * aspergillus japonicus 65000.0 3 PMID:12882638 -3.2.1.15 * aspergillus luchuensis 60000.0 5 PMID:15099902;PMID:16555006;PMID:18631177 -3.2.1.15 * aspergillus niger 106000.0 11 PMID:10675564;PMID:16697346;PMID:16854399;PMID:23069766 -3.2.1.15 * aureobasidium pullulans 42000.0 1 * -3.2.1.15 * bacillus sp. (in: firmicutes) 70000.0 1 * -3.2.1.15 * bipolaris sorokiniana 34000.0 1 PMID:18945012 -3.2.1.15 * borassus flabellifer 66000.0 1 * -3.2.1.15 * botryosphaeria berengeriana 38000.0 1 PMID:11168425 -3.2.1.15 * botrytis cinerea 56800.0 5 PMID:12398287 -3.2.1.15 * burkholderia cepacia 47000.0 3 PMID:17493828 -3.2.1.15 * burkholderia glumae 40000.0 2 PMID:15099902;PMID:18631177 -3.2.1.15 * chondrostereum purpureum 44000.0 6 PMID:15099902;PMID:16061394;PMID:18631177;PMID:19174189 -3.2.1.15 * fomitopsis cytisina 38000.0 1 PMID:11168425 -3.2.1.15 * fragaria x ananassa 41000.0 2 PMID:19968548 -3.2.1.15 * fusarium oxysporum 37500.0 3 PMID:1268232 -3.2.1.15 * fusarium verticillioides 38000.0 4 PMID:11168425;PMID:15462530 -3.2.1.15 * geotrichum klebahnii 40000.0 2 * -3.2.1.15 * geotrichum reessii 40000.0 2 PMID:18321193 -3.2.1.15 * heyndrickxia coagulans 6500.0 1 * -3.2.1.15 * kluyveromyces marxianus 44000.0 4 PMID:10427698;PMID:11998843;PMID:19725536 -3.2.1.15 * lilium longiflorum 44000.0 2 PMID:17097294 -3.2.1.15 * malus domestica 50000.0 1 PMID:19453221 -3.2.1.15 * moniliophthora perniciosa 38530.0 1 PMID:24140149 -3.2.1.15 * mucor flavus 40000.0 2 PMID:18321193 -3.2.1.15 * mucor ramosissimus 24000.0 1 PMID:17123032 -3.2.1.15 * muntingia calabura 85000.0 3 * -3.2.1.15 * musca sp. 90000.0 2 PMID:10872205 -3.2.1.15 * naganishia albida 41000.0 1 PMID:10993164;PMID:4037779 -3.2.1.15 * neurospora crassa 37000.0 2 PMID:1835496 -3.2.1.15 * pectobacterium carotovorum 43500.0 2 PMID:1644302;PMID:2215212 -3.2.1.15 * penicillium capsulatum 56500.0 2 * -3.2.1.15 * penicillium glabrum 20000.0 2 * -3.2.1.15 * penicillium sp. 37500.0 1 * -3.2.1.15 * phytophthora nicotianae 75000.0 15 PMID:18321193 -3.2.1.15 * prunus domestica subsp. insititia 41500.0 1 * -3.2.1.15 * prunus persica 41000.0 1 PMID:16658542 -3.2.1.15 * pyrus communis 41000.0 1 PMID:19968548 -3.2.1.15 * rhizoctonia fragariae 36000.0 1 PMID:884121 -3.2.1.15 * rhizomucor pusillus 32000.0 1 PMID:23125919 -3.2.1.15 * rhizopus arrhizus 31000.0 1 PMID:15160610 -3.2.1.15 * rhizopus stolonifer 60000.0 2 * -3.2.1.15 * saccharomyces cerevisiae 45000.0 2 PMID:10427698 -3.2.1.15 * saccharomyces fragilis 50000.0 4 * -3.2.1.15 * sclerotinia sclerotiorum 18000.0 1 * -3.2.1.15 * solanum lycopersicum 199500.0 12 PMID:15113178;PMID:17244632;PMID:4731966;PMID:6489331;PMID:6617647 -3.2.1.15 * tetracoccosporium sp. 36000.0 1 PMID:17299207 -3.2.1.15 * thermoanaerobacterium thermosulfurigenes 320000.0 1 * -3.2.1.15 * thermoascus aurantiacus 30000.0 2 PMID:17216535;PMID:24159381 -3.2.1.15 * trametes versicolor 63300.0 3 PMID:18253772 -3.2.1.15 * trichoderma harzianum 31000.0 1 PMID:16872705 -3.2.1.15 * trichoderma koningii 32000.0 1 * -3.2.1.15 * trichoderma reesei 66000.0 2 PMID:12668107 -3.2.1.15 * wickerhamomyces anomalus 43000.0 1 PMID:18321193 -3.2.1.150 * geotrichum sp. 97000.0 1 PMID:12374797 -3.2.1.151 * aspergillus aculeatus 34000.0 2 PMID:9884411 -3.2.1.151 * aspergillus japonicus 32000.0 1 PMID:15541296 -3.2.1.151 * aspergillus niger 90500.0 3 PMID:11916668;PMID:18072936 -3.2.1.151 * aspergillus niveus 23500.0 1 PMID:22230786 -3.2.1.151 * geotrichum sp. m128 80500.0 2 PMID:14987996 -3.2.1.151 * lathyrus oleraceus 77000.0 2 PMID:12223734 -3.2.1.151 * paenibacillus sp. 105000.0 2 PMID:16332739 -3.2.1.151 * penicillium canescens 26154.0 2 PMID:20331423 -3.2.1.151 * phanerodontia chrysosporium 130000.0 2 PMID:17922847 -3.2.1.151 * streptomyces avermitilis 92000.0 2 PMID:22941084 -3.2.1.151 * talaromyces verruculosus 70000.0 2 PMID:20331423 -3.2.1.151 * tamarindus indica 13000.0 1 PMID:1416968 -3.2.1.151 * triticum aestivum 32400.0 5 PMID:17692501 -3.2.1.151 * uncultured bacterium 45455.0 1 PMID:20039037 -3.2.1.151 * vigna angularis 33000.0 2 PMID:11230569 -3.2.1.152 * arabidopsis thaliana 112000.0 1 PMID:15247239 -3.2.1.152 * brassica oleracea 141000.0 5 PMID:16788054 -3.2.1.152 * lilium longiflorum 108000.0 5 PMID:15247239;PMID:15713887;PMID:9990135 -3.2.1.153 * chrysolaena herbacea 65700.0 1 PMID:18567893 -3.2.1.153 * cichorium intybus 64000.0 2 * -3.2.1.153 * helianthus tuberosus 75000.0 1 * -3.2.1.153 * hordeum vulgare 33000.0 1 * -3.2.1.153 * triticum aestivum 70000.0 2 PMID:12586886 -3.2.1.154 * actinomyces viscosus 89000.0 1 PMID:3679542 -3.2.1.154 * avena sativa 43000.0 1 PMID:8742337 -3.2.1.154 * cichorium intybus 70000.0 2 PMID:34750605 -3.2.1.154 * lacticaseibacillus paracasei 42000.0 1 * -3.2.1.154 * lactiplantibacillus pentosus 126000.0 2 PMID:12086179 -3.2.1.154 * lolium perenne 69000.0 2 * -3.2.1.154 * pachysandra terminalis 70000.0 3 PMID:21037113 -3.2.1.154 * phleum pratense 78000.0 2 PMID:21317211 -3.2.1.154 * streptococcus mutans 140000.0 2 PMID:1522814;PMID:3308844 -3.2.1.154 * triticum aestivum 70000.0 1 PMID:16330524 -3.2.1.155 * acetivibrio thermocellus 81800.0 1 PMID:16207921 -3.2.1.155 * aspergillus japonicus 32000.0 1 PMID:15541296 -3.2.1.155 * chrysosporium lucknowense 78000.0 1 PMID:15541296 -3.2.1.155 * paenibacillus sp. 105000.0 1 PMID:16332739 -3.2.1.156 * bifidobacterium adolescentis 42000.0 1 PMID:17586675 -3.2.1.157 * alteromonas macleodii 55000.0 1 PMID:29764223 -3.2.1.157 * cellulophaga sp. 54000.0 3 PMID:23690050 -3.2.1.157 * cellulophaga sp. qy3 55800.0 1 PMID:29764223 -3.2.1.157 * flavobacterium sp. ys-80-122 51000.0 1 PMID:29764223 -3.2.1.157 * microbulbifer thermotolerans 55000.0 2 PMID:20686828 -3.2.1.157 * wenyingzhuangia fucanilytica 55000.0 1 PMID:29764223 -3.2.1.157 * zobellia galactanivorans 53400.0 3 PMID:10934194;PMID:29764223 -3.2.1.158 * agarilytica rhodophyticola 90000.0 2 PMID:38144741 -3.2.1.158 * alteromonas agarilytica 360000.0 6 PMID:17513582;PMID:20161978;PMID:29353307;PMID:33035614;PMID:8513809 -3.2.1.158 * catenovulum agarivorans 200000.0 1 PMID:31453692;PMID:32399660 -3.2.1.158 * catenovulum maritimum 180000.0 2 * -3.2.1.158 * catenovulum sediminis 150000.0 2 PMID:31375882;PMID:33035614 -3.2.1.158 * rhodococcus sp. q5 54000.0 1 * -3.2.1.158 * shewanella sp. enk2 50000.0 1 PMID:34436270 -3.2.1.158 * thalassomonas sp. 158000.0 4 PMID:15902469;PMID:22315098;PMID:33035614 -3.2.1.158 * thalassomonas sp. ld5 360000.0 4 PMID:20161978;PMID:29353307;PMID:31453692;PMID:32399660;PMID:33035614;PMID:34863832;PMID:8513809 -3.2.1.158 * thalassotalea agarivorans 87000.0 3 PMID:17177517;PMID:20161978 -3.2.1.159 * bacillus sp. (in: firmicutes) 320000.0 2 PMID:16233232 -3.2.1.159 * vibrio sp. 84000.0 2 PMID:7961439 -3.2.1.161 * cicer arietinum 135000.0 2 PMID:240725 -3.2.1.161 * dalbergia nigrescens 240000.0 3 PMID:16098548;PMID:17998137 -3.2.1.161 * viburnum furcatum 88000.0 1 PMID:18667453 -3.2.1.162 * bacillus sp. (in: firmicutes) 37000.0 1 PMID:24737075 -3.2.1.162 * pseudoalteromonas carrageenovora 109000.0 6 PMID:17269933;PMID:25281802;PMID:29764223 -3.2.1.162 * pseudoalteromonas sp. 100000.0 1 PMID:16926183 -3.2.1.162 * pseudoalteromonas sp. cl19 100000.0 1 PMID:29764223 -3.2.1.163 * aspergillus phoenicis 81000.0 2 PMID:15721331 -3.2.1.163 * homo sapiens 180000.0 3 PMID:16115860;PMID:19722277 -3.2.1.164 * aspergillus niger 60000.0 4 * -3.2.1.164 * fusarium oxysporum 47000.0 1 PMID:17351093 -3.2.1.164 * neurospora crassa 54000.0 2 PMID:20932514 -3.2.1.164 * trichoderma viride 68296.0 6 PMID:12543554;PMID:14565843 -3.2.1.165 * amycolatopsis orientalis 110557.0 2 PMID:16316314;PMID:18976664 -3.2.1.165 * aspergillus flavus 45000.0 1 * -3.2.1.165 * aspergillus oryzae 135000.0 1 PMID:11055393 -3.2.1.165 * penicillium sp. 125000.0 2 * -3.2.1.165 * purpureocillium lilacinum 95000.0 1 PMID:23499103 -3.2.1.165 * talaromyces funiculosus 108000.0 1 * -3.2.1.165 * thermococcus kodakarensis 193000.0 2 PMID:12923090 -3.2.1.165 * trichoderma reesei 105000.0 5 PMID:16349528;PMID:16636831;PMID:20208168 -3.2.1.166 * homo sapiens 80000.0 25 PMID:10514423;PMID:17635638;PMID:20007507;PMID:20399501;PMID:20478306;PMID:20576607;PMID:20840586;PMID:21490396;PMID:21606942;PMID:21746763;PMID:21831044;PMID:22771948;PMID:23415087;PMID:23499528;PMID:24169805;PMID:24395156;PMID:24656445;PMID:25105093 -3.2.1.166 * mammalia 65000.0 3 PMID:20399501;PMID:23499528;PMID:24169805;PMID:24656445;PMID:25105093 -3.2.1.166 * mus musculus 50000.0 4 PMID:12460766;PMID:20399501;PMID:23499528;PMID:24169805;PMID:24656445;PMID:25105093 -3.2.1.166 * rattus norvegicus 50000.0 1 PMID:20840586;PMID:21831044 -3.2.1.167 * escherichia coli 290000.0 1 * -3.2.1.167 * levilactobacillus brevis 71000.0 2 PMID:20075633;PMID:24253830 -3.2.1.167 * scutellaria baicalensis 230000.0 4 PMID:10858442;PMID:8593473 -3.2.1.167 * scutellaria viscidula 58400.0 1 * -3.2.1.168 * acremonium sp. 46000.0 2 PMID:20358178 -3.2.1.169 * chlorocebus aethiops 135000.0 2 PMID:11148210;PMID:11788610 -3.2.1.169 * homo sapiens 130000.0 2 PMID:16844097;PMID:28346407 -3.2.1.169 * rattus norvegicus 106000.0 3 PMID:8034696 -3.2.1.17 * anopheles gambiae 15880.0 2 PMID:18397277 -3.2.1.17 * azumapecten farreri 20010.0 1 PMID:16911829 -3.2.1.17 * bacillus sp. (in: firmicutes) 16464.0 2 PMID:17935850;PMID:18043915 -3.2.1.17 * bacteriophage sp. 19000.0 4 * -3.2.1.17 * bos taurus 15000.0 3 PMID:16309969;PMID:23329238;PMID:6345157;PMID:6807289;PMID:9056247 -3.2.1.17 * brassica sp. 25000.0 1 PMID:11945729 -3.2.1.17 * bufo gargarizans andrewsi 15000.0 2 PMID:16309969;PMID:23329238 -3.2.1.17 * canis lupus familiaris 14500.0 1 PMID:10360984 -3.2.1.17 * carica papaya 250000.0 1 PMID:5633400 -3.2.1.17 * ceratitis capitata 23200.0 1 PMID:12978 -3.2.1.17 * clostridium acetobutylicum 44000.0 2 PMID:1599233 -3.2.1.17 * clostridium phage phi3626 38800.0 1 PMID:12406719 -3.2.1.17 * crassostrea virginica 18400.0 2 * -3.2.1.17 * equus caballus 14660.0 2 PMID:10336875;PMID:5044524 -3.2.1.17 * ficus sp. 29000.0 1 PMID:5794227 -3.2.1.17 * gallus gallus 14600.0 4 PMID:10395829;PMID:20000758;PMID:20178690;PMID:20307635 -3.2.1.17 * ginglymostoma cirratum 14000.0 1 PMID:24084042 -3.2.1.17 * haliotis discus discus 12300.0 1 PMID:23796790 -3.2.1.17 * helicoverpa armigera 15600.0 1 PMID:18615707 -3.2.1.17 * helicoverpa zea 14400.0 1 PMID:15724965 -3.2.1.17 * heliothis virescens 16000.0 2 PMID:8607795 -3.2.1.17 * homo sapiens 21508.0 4 PMID:18248331;PMID:21093056;PMID:5778672;PMID:5815422 -3.2.1.17 * ictalurus punctatus 28000.0 1 PMID:23978564 -3.2.1.17 * lactococcus lactis 57100.0 1 PMID:12634338 -3.2.1.17 * lambdavirus lambda 17900.0 1 PMID:4889461 -3.2.1.17 * larimichthys crocea 21300.0 1 PMID:17225468 -3.2.1.17 * lederbergvirus p22 200000.0 1 PMID:4943672 -3.2.1.17 * liolophura japonica 12000.0 1 * -3.2.1.17 * medicago sativa 36000.0 2 PMID:9601060 -3.2.1.17 * meretrix lusoria 14000.0 4 PMID:24200802 -3.2.1.17 * monodonta labio 12000.0 1 * -3.2.1.17 * musca domestica 13800.0 1 PMID:19161941 -3.2.1.17 * nilssonia gangetica 15400.0 1 PMID:21616 -3.2.1.17 * omphalius pfeifferi 12000.0 1 * -3.2.1.17 * ornithodoros moubata 14000.0 1 PMID:10560138 -3.2.1.17 * oryctolagus cuniculus 14300.0 1 PMID:37167 -3.2.1.17 * papio cynocephalus 15000.0 1 PMID:5105326 -3.2.1.17 * penaeus merguiensis 15000.0 1 PMID:18798009 -3.2.1.17 * penaeus monodon 16320.0 2 PMID:18618291 -3.2.1.17 * phikzvirus phikz 28800.0 1 PMID:18160394 -3.2.1.17 * physella acuta 21200.0 2 PMID:24882016 -3.2.1.17 * pseudomonas aeruginosa 60000.0 4 PMID:25269;PMID:9023918 -3.2.1.17 * pseudomonas phage phikmv 20884.0 1 PMID:15549178 -3.2.1.17 * rhodnius prolixus 15800.0 2 PMID:18258253 -3.2.1.17 * ruditapes philippinarum 20870.0 3 PMID:20144728;PMID:24995730 -3.2.1.17 * saccharopolyspora erythraea 18500.0 1 PMID:25274 -3.2.1.17 * saxidomus purpurata 12000.0 1 * -3.2.1.17 * schistocerca gregaria 15700.0 1 PMID:25972507 -3.2.1.17 * scophthalmus maximus 15700.0 1 PMID:23063540 -3.2.1.17 * streptococcus pneumoniae 55000.0 2 PMID:10411730;PMID:20208162 -3.2.1.17 * tequatrovirus t4 18700.0 2 PMID:21706412;PMID:6345157;PMID:6807289 -3.2.1.17 * thermus virus in93 33141.0 2 PMID:18831965 -3.2.1.170 * thermus thermophilus 125400.0 1 PMID:25712767 -3.2.1.171 * aspergillus aculeatus 62000.0 4 PMID:15299976;PMID:7961884 -3.2.1.171 * irpex lacteus 56000.0 2 PMID:22101785 -3.2.1.172 * bacillus subtilis 43000.0 2 PMID:16781735 -3.2.1.173 * aspergillus aculeatus 66000.0 1 PMID:9576784 -3.2.1.174 * aspergillus aculeatus 84000.0 1 PMID:7972516 -3.2.1.174 * penicillium chrysogenum 96000.0 1 PMID:28110667 -3.2.1.175 * arabidopsis thaliana 98000.0 2 PMID:16990135;PMID:22582100 -3.2.1.176 * acetivibrio thermocellus 80670.0 4 PMID:11782517;PMID:2061292;PMID:8444792 -3.2.1.176 * aspergillus fumigatus 56000.0 1 PMID:32930798 -3.2.1.176 * chrysosporium lucknowense 65000.0 2 * -3.2.1.176 * geotrichum candidum 75000.0 2 PMID:26367132 -3.2.1.176 * heterobasidion irregulare 50000.0 1 PMID:23303184 -3.2.1.176 * limnoria quadripunctata 46500.0 3 PMID:23733951 -3.2.1.176 * melanocarpus albomyces 50000.0 3 PMID:17768346 -3.2.1.176 * mycothermus thermophilus 50400.0 1 PMID:23564627 -3.2.1.176 * neurospora crassa 54741.0 1 PMID:30816014 -3.2.1.176 * paenibacillus sp. 122000.0 2 PMID:12823562 -3.2.1.176 * penicillium digitatum 74000.0 1 PMID:32378080 -3.2.1.176 * penicillium occitanis (nom. inval.) 52500.0 1 * -3.2.1.176 * phialemonium thermophilum 53700.0 2 PMID:18512263 -3.2.1.176 * rasamsonia emersonii 63000.0 2 PMID:25337149 -3.2.1.176 * thermoascus aurantiacus 46900.0 1 PMID:18512263 -3.2.1.176 * thermochaetoides thermophila 54600.0 2 PMID:18512263;PMID:2597698 -3.2.1.176 * thermothielavioides terrestris 51800.0 1 PMID:26265428 -3.2.1.176 * trametes versicolor 55000.0 1 PMID:17333176 -3.2.1.176 * trichoderma pseudokoningii 66000.0 1 PMID:16761094 -3.2.1.176 * trichoderma reesei 63000.0 4 PMID:25337149 -3.2.1.177 * aspergillus oryzae 378000.0 2 PMID:34971412;PMID:38239767 -3.2.1.177 * brassica oleracea var. capitata 89000.0 1 PMID:11402218 -3.2.1.177 * cellvibrio japonicus 113643.0 1 PMID:21426303 -3.2.1.177 * escherichia coli 530000.0 3 PMID:15294295 -3.2.1.177 * saccharolobus solfataricus 92000.0 4 PMID:10801892 -3.2.1.177 * tropaeolum majus 104937.0 1 PMID:11859845 -3.2.1.178 * chondrus crispus 25000.0 1 PMID:36402445 -3.2.1.179 * bacillus sp. (in: firmicutes) 42000.0 2 PMID:10441389;PMID:12777820 -3.2.1.18 * actinomyces viscosus 180000.0 1 PMID:2742753 -3.2.1.18 * aeromonas sp. 130000.0 1 * -3.2.1.18 * arthrobacter sialophilus 87000.0 1 * -3.2.1.18 * arthrobacter sp. 88000.0 2 PMID:629985 -3.2.1.18 * aspergillus fumigatus 42000.0 1 PMID:20652740 -3.2.1.18 * asterias rubens 230000.0 2 PMID:2713101 -3.2.1.18 * bacteroides fragilis 180000.0 5 PMID:1333198;PMID:2742753;PMID:29678922;PMID:6614909 -3.2.1.18 * bifidobacterium bifidum 463000.0 1 PMID:30027820 -3.2.1.18 * bifidobacterium longum subsp. infantis 38000.0 1 PMID:7216169 -3.2.1.18 * clostridium chauvoei 300000.0 3 PMID:12632168;PMID:15942928;PMID:1823619 -3.2.1.18 * clostridium perfringens 129000.0 8 PMID:171212;PMID:24375134;PMID:2885013;PMID:4396647;PMID:8561916 -3.2.1.18 * clostridium tertium 56000.0 1 PMID:9832614 -3.2.1.18 * corynebacterium diphtheriae 70000.0 3 PMID:20007980 -3.2.1.18 * cricetulus griseus 69000.0 2 PMID:11270812 -3.2.1.18 * danio rerio 217000.0 2 PMID:34022291 -3.2.1.18 * entamoeba histolytica 65000.0 1 PMID:12632168;PMID:15942928 -3.2.1.18 * erysipelothrix rhusiopathiae 354000.0 1 * -3.2.1.18 * glutamicibacter nicotianae 65000.0 2 PMID:15809338 -3.2.1.18 * homo sapiens 200000.0 7 PMID:15179041;PMID:25153125;PMID:6735353;PMID:7141414 -3.2.1.18 * influenza a virus 240000.0 6 PMID:12931027;PMID:19133226;PMID:21567198 -3.2.1.18 * influenza a virus h1n1 240000.0 1 PMID:26280677 -3.2.1.18 * influenza a virus h5n1 240000.0 1 PMID:26280677 -3.2.1.18 * micromonospora viridifaciens 30000.0 1 * -3.2.1.18 * oreochromis niloticus 45900.0 3 PMID:25234733 -3.2.1.18 * oryctolagus cuniculus 48000.0 1 PMID:8174546 -3.2.1.18 * paenarthrobacter ureafaciens 88000.0 3 * -3.2.1.18 * paraclostridium sordellii 40000.0 1 * -3.2.1.18 * pasteurella multocida 250000.0 2 PMID:11092845 -3.2.1.18 * patiria pectinifera 360000.0 2 PMID:11026668 -3.2.1.18 * rattus norvegicus 60000.0 2 PMID:3997846;PMID:6723666 -3.2.1.18 * respirovirus muris 60000.0 1 * -3.2.1.18 * streptococcus oralis 329000.0 1 PMID:10707943 -3.2.1.18 * streptococcus pneumoniae 70600.0 1 PMID:4396647;PMID:4402078 -3.2.1.18 * streptococcus sp. 125000.0 5 PMID:38208;PMID:4460881;PMID:6998945 -3.2.1.18 * sus scrofa 64000.0 3 PMID:9703249 -3.2.1.18 * treponema denticola 59800.0 1 PMID:23808705 -3.2.1.18 * triatoma infestans 33000.0 1 PMID:9733752 -3.2.1.18 * trichomonas vaginalis 52000.0 1 * -3.2.1.18 * tritrichomonas mobilensis 630000.0 4 PMID:8824674 -3.2.1.18 * trypanosoma brucei 67000.0 1 PMID:1518530 -3.2.1.18 * trypanosoma rangeli 72700.0 1 PMID:24411449 -3.2.1.18 * trypanosoma vivax 68000.0 2 PMID:15898128 -3.2.1.18 * unidentified influenza virus 270000.0 3 PMID:26280677;PMID:7213637 -3.2.1.18 * vibrio cholerae serotype o1 90000.0 2 * -3.2.1.180 * streptococcus agalactiae 46587.0 2 PMID:19416976 -3.2.1.180 * streptococcus pneumoniae 46079.0 2 PMID:19416976 -3.2.1.180 * streptococcus pyogenes 46100.0 2 PMID:19416976 -3.2.1.181 * flammulina velutipes 30000.0 2 PMID:21653698 -3.2.1.182 * secale cereale 300000.0 3 PMID:10773341 -3.2.1.182 * triticum aestivum 64140.0 8 PMID:10750901;PMID:16751439 -3.2.1.182 * zea mays 120000.0 2 PMID:11106394 -3.2.1.183 * escherichia coli 45000.0 1 PMID:14729696 -3.2.1.183 * neisseria meningitidis 47000.0 1 PMID:15518580 -3.2.1.183 * rattus norvegicus 450000.0 4 PMID:9305887;PMID:9305888 -3.2.1.185 * bifidobacterium longum 74319.0 2 PMID:21914802 -3.2.1.186 * avena sativa 60000.0 1 PMID:8000004 -3.2.1.186 * hellenia speciosa 110000.0 3 PMID:8549824 -3.2.1.186 * solanum torvum 169500.0 4 PMID:16289258;PMID:27055587 -3.2.1.187 * bifidobacterium longum 157000.0 2 PMID:21149454 -3.2.1.188 * avena sativa 350000.0 4 PMID:8000004;PMID:8013661 -3.2.1.188 * parastagonospora avenae 110000.0 1 * -3.2.1.189 * absidia sp. (in: mucoromycotan fungi) 55000.0 1 PMID:20622501 -3.2.1.190 * sus scrofa 47000.0 1 PMID:16079518 -3.2.1.191 * terrabacter ginsenosidimutans 193000.0 5 PMID:20622122;PMID:22450790 -3.2.1.192 * gordonia terrae 156000.0 1 PMID:25457989 -3.2.1.192 * paecilomyces sp. 305000.0 2 PMID:18256474 -3.2.1.193 * aspergillus sp. 80000.0 1 PMID:17268094 -3.2.1.194 * aspergillus sp. 56000.0 1 PMID:22031031 -3.2.1.194 * gordonia terrae 156000.0 1 PMID:25457989 -3.2.1.195 * aspergillus sp. 60000.0 1 * -3.2.1.195 * bifidobacterium longum 95000.0 2 PMID:36673490 -3.2.1.195 * levilactobacillus brevis 123000.0 1 PMID:36673490 -3.2.1.195 * lissachatina fulica 220000.0 1 PMID:36673490 -3.2.1.195 * pseudothermotoga thermarum 55000.0 1 PMID:26725313 -3.2.1.196 * arthrobotrys conoides 87000.0 1 * -3.2.1.196 * corynebacterium glutamicum 417000.0 2 PMID:17600065 -3.2.1.196 * escherichia coli 76000.0 1 PMID:15687211 -3.2.1.196 * synechococcus elongatus 78956.0 1 PMID:17321685 -3.2.1.199 * escherichia coli 70000.0 1 PMID:15294295 -3.2.1.2 * arabidopsis thaliana 67500.0 8 PMID:16698902;PMID:18390594 -3.2.1.2 * bacillus cereus 62500.0 7 PMID:15113834;PMID:8987540 -3.2.1.2 * calystegia sepium 200000.0 4 PMID:11733023 -3.2.1.2 * camelus bactrianus 61000.0 1 PMID:19291574 -3.2.1.2 * dioscorea batatus 60000.0 1 * -3.2.1.2 * dioscorea oppositifolia 56000.0 1 * -3.2.1.2 * entamoeba invadens 45000.0 1 PMID:9027750 -3.2.1.2 * euphorbia esula 35000.0 2 PMID:19924545 -3.2.1.2 * geobacillus stearothermophilus 57000.0 1 * -3.2.1.2 * glycine max 58000.0 7 PMID:7763795;PMID:8552713;PMID:985814 -3.2.1.2 * halobacillus sp. 62000.0 1 * -3.2.1.2 * hordeum vulgare 152000.0 4 PMID:15449730;PMID:4672101;PMID:7765034 -3.2.1.2 * ipomoea batatas 315000.0 6 PMID:5572101 -3.2.1.2 * lathyrus oleraceus 57000.0 2 PMID:16667324 -3.2.1.2 * medicago sativa 65700.0 3 PMID:16662350;PMID:2470731 -3.2.1.2 * oryza sativa 53000.0 2 * -3.2.1.2 * paenibacillus polymyxa 68000.0 4 PMID:2419310 -3.2.1.2 * panicum miliaceum 58000.0 1 PMID:14561508 -3.2.1.2 * phaffia rhodozyma 240000.0 1 PMID:12641711 -3.2.1.2 * priestia megaterium 105000.0 2 PMID:10735188 -3.2.1.2 * sinapis alba 58000.0 1 PMID:14561508 -3.2.1.2 * solanum tuberosum 111000.0 2 * -3.2.1.2 * streptanthus tortuosus 57000.0 1 PMID:8552713 -3.2.1.2 * thermoanaerobacterium thermosulfurigenes 210000.0 2 PMID:2461701 -3.2.1.2 * thermococcus sp. 70000.0 2 PMID:24835094 -3.2.1.2 * thermotoga petrophila 70000.0 1 PMID:26526464 -3.2.1.2 * triticum aestivum 19600.0 1 * -3.2.1.2 * vicia faba 110000.0 2 PMID:5068824 -3.2.1.20 * allium fistulosum 49000.0 3 * -3.2.1.20 * anopheles aquasalis 600000.0 2 PMID:17449310 -3.2.1.20 * apis cerana japonica 82000.0 3 PMID:17151473 -3.2.1.20 * apis florea 75000.0 2 * -3.2.1.20 * apis mellifera 100000.0 2 PMID:11515546;PMID:1397502;PMID:24408102 -3.2.1.20 * aplysia fasciata 255000.0 2 PMID:16290308 -3.2.1.20 * aspergillus awamori 1250000.0 3 * -3.2.1.20 * aspergillus fumigatus 63500.0 1 * -3.2.1.20 * aspergillus nidulans 130000.0 3 PMID:11872475 -3.2.1.20 * aspergillus niger 145000.0 9 PMID:1639895;PMID:20369871 -3.2.1.20 * aspergillus niveus 56000.0 2 PMID:19757138 -3.2.1.20 * bacillus amyloliquefaciens 64000.0 3 PMID:339955 -3.2.1.20 * bacillus cereus 12000.0 1 * -3.2.1.20 * bacillus licheniformis 160000.0 6 PMID:22927369 -3.2.1.20 * bacillus sp. (in: firmicutes) 64000.0 1 PMID:7764968 -3.2.1.20 * bacillus thermoamyloliquefaciens 540000.0 4 PMID:10945254 -3.2.1.20 * beta vulgaris 72000.0 2 * -3.2.1.20 * bos taurus 26000.0 1 PMID:5466143 -3.2.1.20 * brassica oleracea 96000.0 1 PMID:9952433 -3.2.1.20 * caldanaerobacter subterraneus subsp. tengcongensis mb4 89000.0 1 PMID:20075617 -3.2.1.20 * camelus dromedarius 160000.0 2 * -3.2.1.20 * candida albicans 50000.0 1 PMID:20358285 -3.2.1.20 * cyberlindnera fabianii 70000.0 1 PMID:21344231 -3.2.1.20 * drosophila melanogaster 200000.0 5 PMID:104985 -3.2.1.20 * dysdercus peruvianus 431000.0 4 * -3.2.1.20 * entamoeba histolytica 243000.0 3 PMID:14574111 -3.2.1.20 * equus caballus 280000.0 1 PMID:6767500 -3.2.1.20 * erwinia rhapontici 50000.0 1 PMID:19625389 -3.2.1.20 * escherichia coli 144500.0 2 PMID:18171380 -3.2.1.20 * fagopyrum esculentum 88000.0 1 * -3.2.1.20 * ferroplasma acidiphilum 80000.0 9 PMID:15954864;PMID:16478448 -3.2.1.20 * geobacillus thermodenitrificans 45000.0 1 PMID:16581150 -3.2.1.20 * glycine max 115000.0 2 * -3.2.1.20 * homo sapiens 150000.0 9 PMID:18538603;PMID:3128290;PMID:6804453;PMID:7018580;PMID:8575451;PMID:9285074;PMID:9736785 -3.2.1.20 * hordeum vulgare 100000.0 2 PMID:16343940 -3.2.1.20 * lathyrus oleraceus 150000.0 3 PMID:16667773 -3.2.1.20 * lentinula edodes 51000.0 1 * -3.2.1.20 * levilactobacillus brevis 66000.0 3 PMID:16349368 -3.2.1.20 * lipomyces starkeyi 35000.0 1 * -3.2.1.20 * malbranchea cinnamomea 110000.0 1 * -3.2.1.20 * mortierella alliacea 92000.0 3 PMID:12506981 -3.2.1.20 * mucor javanicus 126800.0 2 * -3.2.1.20 * mucor racemosus 114000.0 2 * -3.2.1.20 * oncorhynchus mykiss 365000.0 3 PMID:8215402 -3.2.1.20 * oryctolagus cuniculus 590000.0 2 PMID:2505756 -3.2.1.20 * oryza sativa 96000.0 6 * -3.2.1.20 * panicum miliaceum 86000.0 2 PMID:15845403 -3.2.1.20 * parageobacillus thermoglucosidasius 55000.0 1 PMID:8145 -3.2.1.20 * phaffia rhodozyma 115000.0 2 PMID:16491468 -3.2.1.20 * picrophilus oshimae 440000.0 2 PMID:17015651 -3.2.1.20 * purpureocillium lilacinum 54000.0 1 PMID:12619670 -3.2.1.20 * pyrococcus furiosus 125000.0 1 PMID:11210505 -3.2.1.20 * quesada gigas 61000.0 1 PMID:19766731 -3.2.1.20 * rana japonica 550000.0 3 PMID:8814221 -3.2.1.20 * rattus norvegicus 1300000.0 6 PMID:2141837;PMID:29602;PMID:7027956;PMID:7030134 -3.2.1.20 * rhizobium sp. 59000.0 1 PMID:10388682 -3.2.1.20 * saccharolobus solfataricus 480000.0 7 PMID:11210505;PMID:16580018;PMID:7814342;PMID:9495770 -3.2.1.20 * saccharomyces cerevisiae 63000.0 1 PMID:22927369 -3.2.1.20 * saccharomyces logos 270000.0 1 * -3.2.1.20 * saccharomyces pastorianus 63000.0 1 PMID:365220 -3.2.1.20 * saccharomycopsis fibuligera 135000.0 2 PMID:8948429 -3.2.1.20 * schizosaccharomyces pombe 1120000.0 2 * -3.2.1.20 * solanum tuberosum 120000.0 1 * -3.2.1.20 * sulfolobus acidocaldarius 914000.0 3 PMID:23396915 -3.2.1.20 * sulfurisphaera tokodaii 75600.0 2 PMID:23314368 -3.2.1.20 * sus scrofa 330000.0 7 PMID:1397502;PMID:24408102;PMID:6814909 -3.2.1.20 * talaromyces purpureogenus 120000.0 1 PMID:8547344 -3.2.1.20 * thermoascus aurantiacus 83000.0 1 PMID:20799086 -3.2.1.20 * thermochaetoides thermophila 107000.0 3 * -3.2.1.20 * thermococcus sp. 120000.0 3 PMID:11210505;PMID:8547344 -3.2.1.20 * thermomonospora curvata 70000.0 1 PMID:21344231 -3.2.1.20 * thermoplasma acidophilum 409000.0 1 * -3.2.1.20 * thermotoga maritima 110000.0 2 PMID:10972187 -3.2.1.20 * thermus caldophilus 60000.0 1 * -3.2.1.20 * thermus thermophilus hb27 132000.0 2 PMID:18223075 -3.2.1.20 * trichoderma viride 110000.0 1 PMID:11298225 -3.2.1.20 * vigna radiata 145000.0 3 * -3.2.1.20 * vitis vinifera 100000.0 1 PMID:1397502;PMID:24408102 -3.2.1.20 * zea indurata 65000.0 1 * -3.2.1.20 * zea mays 96000.0 1 PMID:9952433 -3.2.1.200 * arabidopsis thaliana 30000.0 1 PMID:21390509 -3.2.1.200 * bacillus licheniformis 65193.0 1 PMID:25450539 -3.2.1.200 * serratia liquefaciens 52000.0 1 PMID:10949318 -3.2.1.201 * serratia marcescens 62000.0 2 PMID:23824666;PMID:7851747 -3.2.1.202 * vibrio furnissii 112690.0 1 PMID:8969204 -3.2.1.203 * acetivibrio thermocellus 60500.0 1 PMID:7727349 -3.2.1.203 * alicyclobacillus acidocaldarius 56200.0 2 PMID:18991780 -3.2.1.203 * aspergillus fumigatus 88000.0 1 PMID:37216583 -3.2.1.203 * bacillus subtilis 30000.0 1 PMID:23379273 -3.2.1.203 * pseudomonas poae 88000.0 1 PMID:37216583 -3.2.1.204 * bacillus sp. (in: firmicutes) 125000.0 2 PMID:15063208 -3.2.1.206 * lactiplantibacillus plantarum 60000.0 1 PMID:34370148 -3.2.1.206 * olea europaea 130000.0 5 PMID:19689134;PMID:25697790 -3.2.1.206 * prunus dulcis 65000.0 1 * -3.2.1.206 * wickerhamomyces anomalus 60000.0 1 PMID:34370148 -3.2.1.207 * arabidopsis thaliana 104000.0 1 PMID:18972207 -3.2.1.207 * bombyx mori 105000.0 1 PMID:23376632 -3.2.1.207 * bos taurus 290000.0 1 PMID:3122729 -3.2.1.207 * glycine max 110000.0 1 * -3.2.1.207 * homo sapiens 250000.0 5 PMID:10764838;PMID:10929008 -3.2.1.207 * mus musculus 166000.0 7 PMID:10764837;PMID:10921916;PMID:21995826;PMID:29845539 -3.2.1.207 * rattus norvegicus 425000.0 11 PMID:11159920;PMID:11524018;PMID:1910575;PMID:3546312;PMID:3888264;PMID:8910335 -3.2.1.207 * spodoptera frugiperda 106000.0 2 PMID:23376632 -3.2.1.207 * sporothrix schenckii 152700.0 2 PMID:21927828 -3.2.1.207 * sus scrofa 400000.0 5 PMID:12770767;PMID:6373255;PMID:9348113 -3.2.1.207 * vigna radiata 220000.0 2 PMID:2168886;PMID:8314807 -3.2.1.208 * rubrobacter radiotolerans 92900.0 1 PMID:23273275 -3.2.1.208 * selaginella moellendorffii 55300.0 1 PMID:23179444 -3.2.1.208 * thermus thermophilus 205800.0 1 PMID:23273275 -3.2.1.209 * candida albicans 65000.0 10 PMID:16487319;PMID:17588125;PMID:19047746;PMID:19057825 -3.2.1.209 * gallus gallus 50000.0 2 PMID:8797103 -3.2.1.209 * homo sapiens 79000.0 1 PMID:17166854 -3.2.1.209 * saccharomyces cerevisiae 75000.0 4 PMID:1822240;PMID:3049586 -3.2.1.209 * sporothrix schenckii 75000.0 1 PMID:20209334 -3.2.1.209 * sus scrofa 73000.0 1 PMID:9219526 -3.2.1.21 * [candida] sake 220000.0 2 PMID:11732712;PMID:8486554 -3.2.1.21 * acetivibrio thermocellus 50000.0 2 PMID:116657;PMID:1569036;PMID:8795205;PMID:9758774 -3.2.1.21 * agroathelia rolfsii 107000.0 3 PMID:6786226 -3.2.1.21 * alternaria alternata 160000.0 3 * -3.2.1.21 * apis mellifera 72000.0 1 PMID:12020842 -3.2.1.21 * arabidopsis thaliana 63000.0 7 PMID:19965874;PMID:20028477 -3.2.1.21 * aspergillus aculeatus 136000.0 4 PMID:11052758 -3.2.1.21 * aspergillus fumigatus 380000.0 3 * -3.2.1.21 * aspergillus japonicus 240000.0 3 PMID:11052758;PMID:19538132;PMID:3139044 -3.2.1.21 * aspergillus niger 330000.0 11 PMID:10327588;PMID:11052758;PMID:15115178;PMID:19702863;PMID:9438354 -3.2.1.21 * aspergillus oryzae 218000.0 5 PMID:16650812;PMID:21254729;PMID:8795205;PMID:9758774 -3.2.1.21 * aspergillus pulverulentus 240000.0 2 PMID:3139044 -3.2.1.21 * aspergillus terreus 275000.0 1 PMID:16346147 -3.2.1.21 * aspergillus tubingensis 111000.0 1 PMID:11052758 -3.2.1.21 * aspergillus versicolor 99400.0 1 PMID:33636259 -3.2.1.21 * bacillus sp. zj1308 27000.0 1 PMID:26077129 -3.2.1.21 * badhamia polycephala 230000.0 2 PMID:18395487 -3.2.1.21 * beauveria bassiana 600000.0 1 * -3.2.1.21 * bifidobacterium breve 48000.0 1 PMID:9063964 -3.2.1.21 * caldicellulosiruptor saccharolyticus 108000.0 2 PMID:19577189 -3.2.1.21 * camellia sinensis 41000.0 2 PMID:15944750 -3.2.1.21 * carica papaya 54000.0 2 PMID:16894479 -3.2.1.21 * cellulomonas biazotea 109000.0 1 PMID:11570858 -3.2.1.21 * cellulomonas flavigena 210000.0 1 PMID:17334847 -3.2.1.21 * cellulomonas gilvus 80000.0 1 * -3.2.1.21 * cerrena unicolor 47000.0 1 PMID:29418014 -3.2.1.21 * citrus sinensis 65000.0 3 PMID:11559154 -3.2.1.21 * coprinopsis cinerea 302200.0 1 PMID:27030727 -3.2.1.21 * daldinia eschscholtzii 64200.0 1 PMID:17439636 -3.2.1.21 * dictyostelium discoideum 94000.0 1 PMID:8288612 -3.2.1.21 * digitalis lanata 70000.0 2 PMID:11297776 -3.2.1.21 * erinnyis ello 129000.0 1 * -3.2.1.21 * eubacterium sp. 90000.0 1 PMID:8845799 -3.2.1.21 * evernia prunastri 311000.0 1 PMID:3137029 -3.2.1.21 * flavobacterium sp. 49000.0 1 PMID:235305 -3.2.1.21 * fomitopsis palustris 138000.0 1 PMID:18337693 -3.2.1.21 * fusarium oxysporum 110000.0 1 PMID:7925351 -3.2.1.21 * fusarium proliferatum 78700.0 2 * -3.2.1.21 * fusobacterium sp. 320000.0 2 PMID:11440132;PMID:19702863 -3.2.1.21 * galleria mellonella 42000.0 1 PMID:24789069 -3.2.1.21 * gelatoporia subvermispora 110000.0 2 PMID:16882157 -3.2.1.21 * glycine max 165000.0 5 PMID:11730862;PMID:16891302;PMID:20681675 -3.2.1.21 * halalkalibacterium halodurans 51600.0 1 PMID:20618142 -3.2.1.21 * hanseniaspora vineae 295000.0 2 * -3.2.1.21 * homo sapiens 68000.0 8 PMID:11784319;PMID:12667141;PMID:17064932;PMID:3918500;PMID:6796580 -3.2.1.21 * hordeum vulgare 60000.0 1 PMID:7797581;PMID:8068000 -3.2.1.21 * kluyveromyces marxianus 320000.0 2 PMID:12818193;PMID:3314909 -3.2.1.21 * komagataella pastoris 275000.0 2 PMID:16417459 -3.2.1.21 * kuraishia molischiana 330000.0 1 PMID:7670194 -3.2.1.21 * lentinula edodes 100000.0 1 PMID:12590497 -3.2.1.21 * lenzites trabea 320000.0 1 PMID:11440132 -3.2.1.21 * levilactobacillus brevis 330000.0 2 PMID:11440132;PMID:19702863;PMID:9438354 -3.2.1.21 * linum usitatissimum 58000.0 1 PMID:3936419 -3.2.1.21 * lissachatina fulica 220000.0 2 PMID:11732712;PMID:8486554 -3.2.1.21 * listeria innocua clip11262 150000.0 1 PMID:26886583 -3.2.1.21 * littorina kurila 200000.0 1 PMID:18675406 -3.2.1.21 * lotus japonicus 56900.0 2 PMID:18467457 -3.2.1.21 * melanocarpus sp. 102000.0 2 * -3.2.1.21 * metschnikowia pulcherrima 400000.0 2 PMID:18414804 -3.2.1.21 * millerozyma farinosa 220000.0 2 PMID:11732712;PMID:8486554 -3.2.1.21 * mycothermus thermophilus 460000.0 18 PMID:10974122;PMID:15522500;PMID:19611239;PMID:20221730;PMID:27271847 -3.2.1.21 * nakazawaea peltata 43000.0 1 PMID:8795205;PMID:9758774 -3.2.1.21 * nakazawaea wickerhamii 198000.0 3 PMID:3936420;PMID:8987723 -3.2.1.21 * neotermes koshunensis 60000.0 1 * -3.2.1.21 * niallia circulans subsp. alkalophilus 51300.0 1 PMID:8481013 -3.2.1.21 * olea europaea 65000.0 1 PMID:21493168 -3.2.1.21 * orobanche minor 33000.0 1 PMID:20208378 -3.2.1.21 * oryza sativa 66000.0 7 PMID:16880561;PMID:19587102;PMID:20570296 -3.2.1.21 * paecilomyces sp. 305000.0 2 PMID:18256474 -3.2.1.21 * paenibacillus polymyxa 52000.0 2 PMID:116657;PMID:1569036;PMID:17585934 -3.2.1.21 * paenibacillus sp. 50000.0 1 PMID:16205911 -3.2.1.21 * pantoea agglomerans 122000.0 1 * -3.2.1.21 * pectobacterium carotovorum 54000.0 1 * -3.2.1.21 * penicillium aurantiogriseum 247000.0 4 PMID:10380623 -3.2.1.21 * penicillium brasilianum 115000.0 1 PMID:19756584 -3.2.1.21 * penicillium decumbens 460000.0 4 * -3.2.1.21 * phanerodontia chrysosporium 133000.0 6 PMID:12619666;PMID:16896601;PMID:17376440 -3.2.1.21 * pholiota adiposa 60000.0 2 * -3.2.1.21 * phoma sp. 440000.0 2 PMID:21617347 -3.2.1.21 * phytophthora infestans 154000.0 3 PMID:11909624 -3.2.1.21 * piromyces sp. 91457.0 1 PMID:12485115 -3.2.1.21 * plumeria obtusa 60600.0 2 PMID:16894479 -3.2.1.21 * prunus armeniaca 66000.0 1 * -3.2.1.21 * prunus avium 70000.0 2 PMID:11297776 -3.2.1.21 * prunus dulcis 135000.0 1 PMID:3929833 -3.2.1.21 * pseudomonas sp. 33000.0 2 PMID:15053533 -3.2.1.21 * pyricularia oryzae 240000.0 1 PMID:29039 -3.2.1.21 * pyrococcus furiosus 120000.0 4 PMID:24053641;PMID:24598756;PMID:33631310;PMID:8798600 -3.2.1.21 * rasamsonia emersonii 260000.0 6 PMID:15555940 -3.2.1.21 * rattus sp. 58000.0 1 PMID:2304 -3.2.1.21 * rhizobium leguminosarum 74000.0 1 * -3.2.1.21 * rhizomucor miehei 76500.0 2 PMID:25577102 -3.2.1.21 * rhynchophorus palmarum 60000.0 2 PMID:19611239;PMID:20221730 -3.2.1.21 * rhynchosciara americana 106000.0 1 PMID:6412680 -3.2.1.21 * ruminococcus albus 85000.0 2 PMID:3918007 -3.2.1.21 * saccharolobus solfataricus 313000.0 6 PMID:21898127;PMID:24060745 -3.2.1.21 * saccharomyces cerevisiae 313000.0 3 * -3.2.1.21 * saccharomycopsis fibuligera 220000.0 1 PMID:17333092 -3.2.1.21 * saccharophagus degradans 62000.0 1 PMID:23749228 -3.2.1.21 * schizophyllum commune 110000.0 2 * -3.2.1.21 * schwanniomyces etchellsii 340000.0 8 PMID:12720410;PMID:12818193;PMID:15549293;PMID:3314909;PMID:9185848 -3.2.1.21 * schwanniomyces vanrijiae 100000.0 1 PMID:12590497 -3.2.1.21 * sclerotinia sclerotiorum 240000.0 5 PMID:14566067;PMID:14981282;PMID:3139044 -3.2.1.21 * scytalidium lignicola 74000.0 2 PMID:18548555 -3.2.1.21 * shewanella sp. 32197.0 1 PMID:18247390 -3.2.1.21 * shewanella sp. g5 140000.0 2 * -3.2.1.21 * sporotrichum pulverulentum 182000.0 1 * -3.2.1.21 * stachybotrys sp. 170000.0 3 PMID:17938914 -3.2.1.21 * streptomyces sp. 52600.0 2 PMID:10089468 -3.2.1.21 * sus scrofa 59000.0 1 PMID:3146970 -3.2.1.21 * talaromyces funiculosus 230000.0 3 * -3.2.1.21 * talaromyces purpureogenus 110000.0 2 PMID:20043150 -3.2.1.21 * talaromyces verruculosus 116000.0 1 PMID:19538132;PMID:20031400;PMID:20382376 -3.2.1.21 * termitomyces clypeatus 450000.0 5 PMID:1900198;PMID:19538132;PMID:20031400;PMID:20382376 -3.2.1.21 * terrabacter ginsenosidimutans 193000.0 2 PMID:20622122 -3.2.1.21 * thermoascus aurantiacus 350000.0 7 PMID:11115405;PMID:12630320;PMID:16614858;PMID:6781492 -3.2.1.21 * thermobispora bispora 52280.0 1 PMID:1482172 -3.2.1.21 * thermochaetoides thermophila 43000.0 2 PMID:11930943 -3.2.1.21 * thermoclostridium stercorarium 105000.0 2 * -3.2.1.21 * thermofilum pendens 77800.0 1 PMID:23266119 -3.2.1.21 * thermomyces dupontii 113000.0 3 PMID:16446002;PMID:26649918 -3.2.1.21 * thermomyces lanuginosus 200000.0 3 * -3.2.1.21 * thermophilic anaerobic bacterium 50000.0 1 PMID:3117033 -3.2.1.21 * thermoplasma acidophilum 114000.0 3 PMID:19458917 -3.2.1.21 * thermothelomyces thermophilus 240000.0 1 PMID:3139044 -3.2.1.21 * thermotoga maritima 80000.0 1 * -3.2.1.21 * thermotoga neapolitana 56200.0 1 PMID:16082555 -3.2.1.21 * thermotoga petrophila 182000.0 7 PMID:22714267;PMID:25637167 -3.2.1.21 * thermus sp. 48000.0 1 * -3.2.1.21 * thermus thermophilus 53000.0 4 PMID:10580648;PMID:21058504;PMID:25152415 -3.2.1.21 * thielaviopsis paradoxa 170000.0 2 PMID:10956173 -3.2.1.21 * trametes versicolor 300000.0 1 * -3.2.1.21 * trichocladium griseum 156000.0 2 PMID:8595591 -3.2.1.21 * trichoderma koningii 39800.0 1 * -3.2.1.21 * trichoderma reesei 114000.0 3 PMID:1599951;PMID:3109900 -3.2.1.21 * trichoderma viride 76000.0 2 PMID:3917923 -3.2.1.21 * triglochin maritima 290000.0 4 * -3.2.1.21 * triticum aestivum 300000.0 1 PMID:10750901 -3.2.1.21 * uncultured bacterium 101000.0 4 PMID:19584532;PMID:20890102 -3.2.1.21 * uncultured rumen bacterium 80000.0 1 PMID:22085266 -3.2.1.21 * vanilla planifolia 201000.0 2 PMID:12720410;PMID:9185848 -3.2.1.21 * verruciconidia persicina 128000.0 1 PMID:9291624 -3.2.1.21 * vitis vinifera 60000.0 1 * -3.2.1.21 * volvariella volvacea 380000.0 2 PMID:16215851 -3.2.1.21 * weissella cibaria 50000.0 2 PMID:23221534 -3.2.1.21 * wickerhamomyces anomalus 360000.0 2 PMID:12818193;PMID:3314909 -3.2.1.21 * zea mays 62400.0 2 PMID:18282703;PMID:7797581;PMID:8068000 -3.2.1.212 * formosa algae 101200.0 2 PMID:28031251;PMID:35489196 -3.2.1.212 * lambis sp. 50000.0 1 * -3.2.1.212 * wenyingzhuangia fucanilytica 44900.0 2 PMID:38203394 -3.2.1.214 * parabacteroides distasonis 110000.0 1 PMID:29763309 -3.2.1.216 * flavobacterium johnsoniae 433000.0 1 PMID:34728215 -3.2.1.216 * sulfolobus acidocaldarius 914000.0 3 PMID:23396915 -3.2.1.217 * bombyx mori 787000.0 1 PMID:33742736 -3.2.1.22 * acer pseudoplatanus 167000.0 2 PMID:4561015 -3.2.1.22 * arachis hypogaea 30000.0 1 * -3.2.1.22 * aspergillus ficuum 70700.0 1 PMID:2287609 -3.2.1.22 * aspergillus nidulans 370000.0 4 PMID:20681989;PMID:8405947 -3.2.1.22 * aspergillus niger 350000.0 4 PMID:14112;PMID:3007446 -3.2.1.22 * aspergillus oryzae 64000.0 1 PMID:18846399 -3.2.1.22 * aspergillus tamarii 265000.0 3 PMID:6331398;PMID:6331399 -3.2.1.22 * aspergillus terreus 350000.0 6 PMID:18543114;PMID:21331589 -3.2.1.22 * bacteroides ovatus 85000.0 2 PMID:2981815 -3.2.1.22 * bifidobacterium bifidum 243000.0 3 PMID:19005653 -3.2.1.22 * bifidobacterium breve 160000.0 5 PMID:12236697;PMID:18564335;PMID:25353020 -3.2.1.22 * bispora sp. 64000.0 2 PMID:20591661 -3.2.1.22 * cajanus indicus 87000.0 1 PMID:4561015 -3.2.1.22 * caldanaerobius polysaccharolyticus 176000.0 2 PMID:12236697;PMID:25353020 -3.2.1.22 * carica papaya 170000.0 4 PMID:16325871 -3.2.1.22 * castanea sativa 215000.0 2 * -3.2.1.22 * citrullus lanatus 45000.0 1 PMID:14112;PMID:3007446 -3.2.1.22 * cocos nucifera 26600.0 3 * -3.2.1.22 * coffea sp. 34000.0 2 PMID:1662502;PMID:18834998;PMID:4561015 -3.2.1.22 * corynebacterium murisepticum 320000.0 2 * -3.2.1.22 * cucumis sativus 50000.0 2 PMID:16661511 -3.2.1.22 * cyamopsis tetragonoloba 25000.0 1 PMID:4561015 -3.2.1.22 * debaryomyces hansenii 61000.0 4 PMID:19226141 -3.2.1.22 * dictyostelium discoideum 170000.0 1 PMID:10894;PMID:19629597 -3.2.1.22 * diehliomyces microsporus 62000.0 1 PMID:26184012;PMID:9741105 -3.2.1.22 * escherichia coli 51000.0 1 PMID:2831880 -3.2.1.22 * flavobacterium sp. 82000.0 1 PMID:20714719 -3.2.1.22 * fusarium sp. 320000.0 4 PMID:19288093 -3.2.1.22 * ganoderma lucidum 249000.0 2 PMID:12913291 -3.2.1.22 * geobacillus stearothermophilus 325000.0 6 PMID:10418141;PMID:6257360 -3.2.1.22 * glycine max 38000.0 2 PMID:11524115;PMID:8828798 -3.2.1.22 * halalkalibacterium halodurans 51000.0 1 PMID:18776668 -3.2.1.22 * haliotis corrugata 43000.0 2 PMID:19002810 -3.2.1.22 * hapsidospora chrysogena 240000.0 1 PMID:19809163 -3.2.1.22 * helianthus annuus 159000.0 4 PMID:12882552;PMID:4561015 -3.2.1.22 * homo sapiens 150000.0 16 PMID:11049747;PMID:16347214;PMID:17555407;PMID:201618;PMID:210818;PMID:23935525;PMID:4629399;PMID:4733088;PMID:6256390;PMID:661600;PMID:8039705;PMID:8104 -3.2.1.22 * lactobacillus acidophilus 260000.0 2 PMID:21827767 -3.2.1.22 * lathyrus oleraceus 121600.0 2 PMID:4561015 -3.2.1.22 * lens culinaris 160000.0 2 PMID:6296089;PMID:6325188 -3.2.1.22 * limosilactobacillus fermentum 336000.0 2 PMID:17048069 -3.2.1.22 * lupinus angustifolius 70800.0 2 * -3.2.1.22 * medicago sativa 57000.0 2 PMID:4561015 -3.2.1.22 * monascus pilosus 150000.0 1 PMID:16347214;PMID:4629399;PMID:8104 -3.2.1.22 * mus musculus 150000.0 1 PMID:16347214;PMID:4629399;PMID:8104 -3.2.1.22 * oryza sativa 42000.0 7 PMID:12423882;PMID:17284836 -3.2.1.22 * penicillium canescens 81858.0 4 PMID:18294137 -3.2.1.22 * phanerodontia chrysosporium 250000.0 1 PMID:10085226 -3.2.1.22 * phaseolus vulgaris 149300.0 3 PMID:4561015;PMID:7703901 -3.2.1.22 * phlebia radiata 64220.0 6 PMID:12916725 -3.2.1.22 * pleurotus floridanus 99000.0 1 PMID:17536334 -3.2.1.22 * poterioochromonas malhamensis 360000.0 1 * -3.2.1.22 * prunus dulcis 33000.0 2 PMID:4561015;PMID:6032983 -3.2.1.22 * pseudoalteromonas sp. 170000.0 5 PMID:10894;PMID:12236697;PMID:19629597;PMID:25353020;PMID:27033343 -3.2.1.22 * pseudoalteromonas sp. kmm 701 160000.0 1 PMID:25353020;PMID:27033343 -3.2.1.22 * rasamsonia emersonii 110000.0 2 PMID:21193820 -3.2.1.22 * rhizomucor miehei 312000.0 1 PMID:22349190 -3.2.1.22 * rhizopus sp. 78000.0 1 * -3.2.1.22 * rhizopus sp. accc 30795 210000.0 2 PMID:19996679 -3.2.1.22 * saccharolobus solfataricus 225000.0 1 PMID:16547025 -3.2.1.22 * saccharomyces cerevisiae 320000.0 2 PMID:20592022 -3.2.1.22 * saccharomyces pastorianus 300000.0 1 PMID:216315 -3.2.1.22 * saccharopolyspora erythraea 45000.0 3 PMID:15538554 -3.2.1.22 * saccharum officinarum 47000.0 1 PMID:6279579 -3.2.1.22 * solanum lycopersicum 44000.0 3 PMID:11432942 -3.2.1.22 * sphingomonas sp. 85500.0 2 PMID:23124345 -3.2.1.22 * spodoptera frugiperda 94000.0 2 PMID:11163310 -3.2.1.22 * stachys affinis 42000.0 1 PMID:19002810 -3.2.1.22 * tachigali multijuga 38000.0 2 PMID:1662502;PMID:18834998 -3.2.1.22 * talaromyces flavus 63000.0 1 PMID:17049401 -3.2.1.22 * tenebrio molitor 49000.0 1 PMID:11163310 -3.2.1.22 * thermomyces lanuginosus 93000.0 2 PMID:11078955;PMID:17008008 -3.2.1.22 * thermotoga maritima 125000.0 3 PMID:11210503;PMID:26184012;PMID:9741105 -3.2.1.22 * thermotoga neapolitana 61000.0 2 PMID:11210503;PMID:8979350 -3.2.1.22 * thermus sp. t2 400000.0 2 PMID:11282611 -3.2.1.22 * trametes cinnabarina 210000.0 1 PMID:19996679 -3.2.1.22 * trichoderma reesei 50000.0 1 PMID:8390816 -3.2.1.22 * trifolium repens 43000.0 1 PMID:33663 -3.2.1.22 * umbelopsis vinacea 270000.0 4 PMID:10427697;PMID:19809163;PMID:9145516 -3.2.1.22 * vicia dumetorum 195000.0 2 PMID:4561015 -3.2.1.22 * vicia faba 209000.0 4 PMID:18800298;PMID:24241740;PMID:4561015 -3.2.1.22 * vicia sativa 166000.0 3 PMID:4561015 -3.2.1.22 * vigna radiata 160000.0 2 PMID:6296089;PMID:6325188 -3.2.1.22 * vigna radiata var. radiata 209000.0 2 PMID:4561015 -3.2.1.22 * vigna unguiculata 111000.0 4 * -3.2.1.22 * yersinia pestis 80000.0 1 PMID:18685186 -3.2.1.220 * carapichea ipecacuanha 61800.0 1 PMID:18927081 -3.2.1.225 * candidatus mycosynbacter amalyticus 202115.0 2 PMID:37076525 -3.2.1.225 * dysgonomonas gadei 519438.0 6 PMID:37076525 -3.2.1.225 * nocardia brasiliensis 123934.0 2 PMID:37076525 -3.2.1.23 * actinomyces viscosus 420000.0 1 PMID:17574 -3.2.1.23 * alkalilactibacillus ikkensis 115000.0 1 PMID:20718293 -3.2.1.23 * arabidopsis thaliana 119544.0 5 PMID:18359051 -3.2.1.23 * arthrobacter sp. 660000.0 9 PMID:12949099;PMID:16171818;PMID:19631003;PMID:19771412;PMID:21464592 -3.2.1.23 * aspergillus aculeatus 130000.0 2 PMID:11086688;PMID:19453169 -3.2.1.23 * aspergillus carbonarius 152000.0 4 PMID:18401743 -3.2.1.23 * aspergillus japonicus 27000.0 1 * -3.2.1.23 * aspergillus niger 173000.0 5 PMID:116848;PMID:19806354 -3.2.1.23 * aspergillus oryzae 122000.0 3 PMID:16865665;PMID:236999;PMID:30980597 -3.2.1.23 * averrhoa carambola 130000.0 6 PMID:15652572 -3.2.1.23 * bacillus licheniformis 80000.0 1 PMID:9625788 -3.2.1.23 * bacillus sp. (in: firmicutes) 484000.0 4 PMID:18401743 -3.2.1.23 * bacteroides polypragmatus 220000.0 2 * -3.2.1.23 * bifidobacterium adolescentis 350000.0 2 PMID:10742215 -3.2.1.23 * bifidobacterium bifidum 362000.0 1 * -3.2.1.23 * bifidobacterium longum 357000.0 1 * -3.2.1.23 * bifidobacterium longum subsp. infantis 470000.0 2 PMID:11954789 -3.2.1.23 * bispora sp. 130000.0 2 PMID:11086688;PMID:19453169 -3.2.1.23 * bos taurus 68000.0 2 PMID:26842 -3.2.1.23 * caldicellulosiruptor saccharolyticus 240000.0 4 PMID:19662397;PMID:20972818;PMID:2105216 -3.2.1.23 * canis lupus familiaris 190000.0 1 PMID:8243059 -3.2.1.23 * clostridium perfringens 88150.0 2 PMID:19630404 -3.2.1.23 * corynebacterium murisepticum 190500.0 2 PMID:2492796 -3.2.1.23 * daucus carota 104000.0 2 * -3.2.1.23 * erythrina variegata 78000.0 2 PMID:17761389;PMID:19666723 -3.2.1.23 * escherichia coli 521000.0 7 * -3.2.1.23 * felis catus 115000.0 3 PMID:106876;PMID:18421424 -3.2.1.23 * flavobacterium sp. 114300.0 1 PMID:16193277 -3.2.1.23 * geobacillus stearothermophilus 215000.0 4 PMID:17761389;PMID:18420605;PMID:19666723;PMID:6142 -3.2.1.23 * haloferax volcanii 180000.0 2 PMID:9048905 -3.2.1.23 * halorubrum lacusprofundi 100000.0 2 PMID:23320757 -3.2.1.23 * hamamotoa singularis 53000.0 1 PMID:14969418 -3.2.1.23 * heyndrickxia coagulans 430000.0 1 PMID:6787981 -3.2.1.23 * homo sapiens 380000.0 3 PMID:19573604;PMID:3109378 -3.2.1.23 * irpex lacteus 51000.0 2 PMID:2158993 -3.2.1.23 * kluyveromyces lactis 630000.0 5 PMID:3145202 -3.2.1.23 * kluyveromyces marxianus 251000.0 12 PMID:17625262 -3.2.1.23 * lacticaseibacillus casei 117000.0 3 PMID:37599861 -3.2.1.23 * lactiplantibacillus pentosus 105000.0 3 PMID:20669255 -3.2.1.23 * lactiplantibacillus plantarum wcfs1 107000.0 5 PMID:20385377 -3.2.1.23 * lactobacillus acidophilus 105000.0 6 PMID:17227458 -3.2.1.23 * lactobacillus delbrueckii 400000.0 3 PMID:19786095;PMID:8119903 -3.2.1.23 * lactobacillus helveticus 257000.0 2 PMID:6434507 -3.2.1.23 * lathyrus oleraceus 228000.0 3 PMID:19552429 -3.2.1.23 * ligilactobacillus murinus 170000.0 1 PMID:8526517 -3.2.1.23 * limosilactobacillus reuteri 105000.0 6 PMID:16819907 -3.2.1.23 * marchantia polymorpha 67000.0 2 PMID:9557875 -3.2.1.23 * medicago sativa 260000.0 3 * -3.2.1.23 * mus musculus 520000.0 3 PMID:19147730 -3.2.1.23 * neurospora crassa 156000.0 4 PMID:237204;PMID:5563865 -3.2.1.23 * niallia circulans 67000.0 2 PMID:9557875 -3.2.1.23 * oreochromis niloticus 71000.0 1 * -3.2.1.23 * oryza sativa 97000.0 4 PMID:12723614 -3.2.1.23 * paecilomyces variotii 94000.0 1 * -3.2.1.23 * paenibacillus macerans 320000.0 2 * -3.2.1.23 * papiliotrema laurentii 200000.0 2 PMID:2492796 -3.2.1.23 * penicillium canescens 560000.0 2 * -3.2.1.23 * penicillium chrysogenum 270000.0 2 PMID:11162383 -3.2.1.23 * penicillium citrinum 110000.0 3 * -3.2.1.23 * penicillium multicolor 130000.0 2 * -3.2.1.23 * phaseolus vulgaris 75000.0 3 PMID:12756912 -3.2.1.23 * planococcus sp. (in: firmicutes) 155000.0 2 PMID:10831422 -3.2.1.23 * priestia megaterium 150000.0 6 PMID:10572953;PMID:18682899;PMID:4205741;PMID:4959088;PMID:9721318 -3.2.1.23 * prunus persica 42000.0 1 PMID:12661763 -3.2.1.23 * pseudoalteromonas haloplanktis 118000.0 1 PMID:11282601 -3.2.1.23 * pyrococcus furiosus 59450.0 1 PMID:24462527 -3.2.1.23 * rattus norvegicus 347000.0 13 PMID:11082284;PMID:418065;PMID:7826352;PMID:8329173;PMID:9247702 -3.2.1.23 * rhizobium leguminosarum 122000.0 1 * -3.2.1.23 * rhizomucor sp. 250000.0 2 PMID:10572953;PMID:4205741 -3.2.1.23 * saccharolobus solfataricus 240000.0 8 PMID:19662397;PMID:2105216;PMID:2121622;PMID:23411285;PMID:24114556 -3.2.1.23 * saccharomyces fragilis 203000.0 1 * -3.2.1.23 * saccharopolyspora rectivirgula 145000.0 1 * -3.2.1.23 * scopulariopsis sp. 95000.0 1 * -3.2.1.23 * sterigmatomyces elviae 170000.0 2 PMID:8526517 -3.2.1.23 * streptococcus mitis 264000.0 2 PMID:19633119 -3.2.1.23 * streptococcus pneumoniae 135000.0 2 PMID:19841081 -3.2.1.23 * streptococcus thermophilus 470000.0 6 PMID:20472057 -3.2.1.23 * tenebrio molitor 64000.0 2 PMID:12535683 -3.2.1.23 * thermoanaerobacter sp. 154000.0 1 * -3.2.1.23 * thermoanaerobacterium thermosulfurigenes 178000.0 1 PMID:8968953 -3.2.1.23 * thermomyces dupontii 50000.0 1 PMID:16446002 -3.2.1.23 * thermomyces lanuginosus 220000.0 2 PMID:10974122;PMID:7747967 -3.2.1.23 * thermotoga maritima 129501.0 1 PMID:15479416 -3.2.1.23 * thermus aquaticus 750000.0 3 * -3.2.1.23 * thermus sp. 550000.0 3 PMID:9757561 -3.2.1.23 * torulopsis sphaerica 233000.0 1 * -3.2.1.23 * trametes cinnabarina 110000.0 2 * -3.2.1.23 * treponema phagedenis 580000.0 2 * -3.2.1.23 * uncultured soil bacterium 90000.0 2 PMID:20614217 -3.2.1.23 * vigna radiata 87000.0 5 PMID:11393513 -3.2.1.23 * wickerhamiella versatilis 226000.0 1 * -3.2.1.24 * aspergillus oryzae 49000.0 1 PMID:7118857 -3.2.1.24 * aspergillus phoenicis 51000.0 1 PMID:7011404 -3.2.1.24 * aspergillus sp. 412000.0 2 PMID:7632718 -3.2.1.24 * canavalia ensiformis 230000.0 7 PMID:1156387;PMID:12801516;PMID:19129634;PMID:23422784;PMID:3370126;PMID:5145 -3.2.1.24 * candida albicans 417000.0 4 PMID:10336985;PMID:15128678;PMID:8454197 -3.2.1.24 * capsicum annuum 500000.0 3 PMID:21030387 -3.2.1.24 * citrullus lanatus 270000.0 1 * -3.2.1.24 * equus caballus 154000.0 1 PMID:22578623 -3.2.1.24 * gallus gallus 480000.0 2 PMID:6465;PMID:9498562 -3.2.1.24 * helianthus annuus 260000.0 1 * -3.2.1.24 * homo sapiens 280000.0 6 PMID:27814608;PMID:3954735 -3.2.1.24 * lablab purpureus 230000.0 2 PMID:1156387;PMID:12801516;PMID:19129634;PMID:23422784 -3.2.1.24 * lupinus angustifolius 300000.0 1 * -3.2.1.24 * macaca radiata 45000.0 1 PMID:3140784 -3.2.1.24 * medicago sativa 230000.0 5 PMID:6772149 -3.2.1.24 * mus musculus 670000.0 4 PMID:10089383;PMID:9305783;PMID:9355733 -3.2.1.24 * phaseolus vulgaris 220000.0 1 PMID:837933 -3.2.1.24 * picrophilus oshimae 220000.0 3 PMID:17015651;PMID:1849817 -3.2.1.24 * prunus serotina 150000.0 1 * -3.2.1.24 * pyricularia oryzae 63000.0 3 PMID:19621226 -3.2.1.24 * rattus sp. 460000.0 14 PMID:17015651;PMID:1849817;PMID:1885615;PMID:26838;PMID:26839;PMID:624714;PMID:6465;PMID:8033914;PMID:863880;PMID:9498562 -3.2.1.24 * rhodococcus erythropolis 32000.0 1 * -3.2.1.24 * saccharolobus solfataricus 363000.0 2 PMID:20696204 -3.2.1.24 * saccharomyces cerevisiae 560000.0 3 PMID:3281936;PMID:338603;PMID:4570370 -3.2.1.24 * solanum lycopersicum 230000.0 4 PMID:1156387;PMID:12801516;PMID:19129634;PMID:20798166;PMID:23422784 -3.2.1.24 * styela plicata 275000.0 2 PMID:6671967 -3.2.1.24 * sus scrofa 275000.0 4 PMID:10407159;PMID:4690228 -3.2.1.24 * thermotoga maritima 230000.0 2 PMID:1156387;PMID:12801516;PMID:19129634;PMID:23422784 -3.2.1.24 * triticum aestivum 197000.0 1 * -3.2.1.24 * trypanosoma cruzi 359000.0 3 PMID:1472763;PMID:9858640 -3.2.1.24 * vigna umbellata 329000.0 1 PMID:9614691 -3.2.1.24 * yarrowia lipolytica 220000.0 1 PMID:17015651;PMID:1849817 -3.2.1.25 * agroathelia rolfsii 57500.0 1 * -3.2.1.25 * aplysia fasciata 130000.0 1 PMID:16029907 -3.2.1.25 * aspergillus aculeatus 130000.0 2 PMID:17651209 -3.2.1.25 * aspergillus niger 180000.0 5 PMID:10553664;PMID:26672;PMID:623772;PMID:845158 -3.2.1.25 * bacillus sp. (in: firmicutes) 94000.0 2 PMID:18931445 -3.2.1.25 * cellulomonas fimi 130000.0 1 PMID:10347049 -3.2.1.25 * ceratonia siliqua 100000.0 2 * -3.2.1.25 * cutaneotrichosporon cutaneum 193000.0 2 * -3.2.1.25 * cyamopsis tetragonoloba 59000.0 1 * -3.2.1.25 * gallus gallus 10000.0 1 PMID:5021602 -3.2.1.25 * helix pomatia 94000.0 1 * -3.2.1.25 * homo sapiens 160000.0 13 PMID:18800177;PMID:2808324;PMID:6667923;PMID:8652632 -3.2.1.25 * hordeum vulgare 88000.0 1 PMID:4429703 -3.2.1.25 * medicago sativa 100000.0 2 * -3.2.1.25 * phlebia radiata 104600.0 3 PMID:17650684 -3.2.1.25 * polyporus sulfureus 64000.0 1 PMID:6478 -3.2.1.25 * pyrococcus horikoshii 250000.0 3 PMID:11900558 -3.2.1.25 * solanum lycopersicum 56000.0 1 PMID:12012251 -3.2.1.25 * thermoascus aurantiacus 99900.0 1 * -3.2.1.25 * thermotoga maritima 93200.0 1 * -3.2.1.25 * thermotoga neapolitana 200000.0 2 PMID:11210502;PMID:8979350 -3.2.1.25 * tremella fuciformis 140000.0 1 PMID:26672;PMID:623772 -3.2.1.25 * trichoderma reesei 105000.0 1 * -3.2.1.25 * trifolium repens 43000.0 2 PMID:8921369 -3.2.1.26 * agave tequilana 70400.0 2 PMID:22558253 -3.2.1.26 * agroathelia rolfsii 220000.0 1 * -3.2.1.26 * arthrobacter globiformis 60000.0 1 PMID:15127791 -3.2.1.26 * aspergillus ficuum 84000.0 1 PMID:7669814 -3.2.1.26 * aspergillus flavus 67000.0 1 * -3.2.1.26 * aspergillus japonicus 236000.0 3 PMID:7764333;PMID:8358833 -3.2.1.26 * aspergillus nidulans 185000.0 5 PMID:8814228 -3.2.1.26 * aspergillus niger 340000.0 9 PMID:12423880;PMID:17293485;PMID:7764333;PMID:8358833 -3.2.1.26 * aspergillus ochraceus 135000.0 5 PMID:11693382;PMID:5647272 -3.2.1.26 * aspergillus parasiticus 136000.0 1 * -3.2.1.26 * aspergillus phoenicis 136000.0 1 * -3.2.1.26 * aspergillus terreus 74800.0 3 PMID:24307498 -3.2.1.26 * aureobasidium pullulans 430000.0 1 PMID:17609167 -3.2.1.26 * aureobasidium sp. 346000.0 3 * -3.2.1.26 * avena sativa 108000.0 2 * -3.2.1.26 * azotobacter chroococcum 59000.0 2 PMID:29055702 -3.2.1.26 * bacillus cereus 26000.0 1 PMID:28731585 -3.2.1.26 * bambusa oldhamii 77500.0 7 PMID:16608237;PMID:19010503 -3.2.1.26 * beta vulgaris 280000.0 2 PMID:16661402;PMID:22905381 -3.2.1.26 * bifidobacterium adolescentis 74000.0 3 PMID:20380746 -3.2.1.26 * bifidobacterium animalis subsp. lactis 60000.0 1 PMID:15214632 -3.2.1.26 * bifidobacterium breve 74000.0 2 PMID:28731585 -3.2.1.26 * bifidobacterium longum 60000.0 2 PMID:21418142 -3.2.1.26 * bifidobacterium longum subsp. infantis 72000.0 2 PMID:12460425;PMID:12590504 -3.2.1.26 * bombyx mori 57000.0 2 PMID:29055702 -3.2.1.26 * carica papaya 52000.0 1 * -3.2.1.26 * citrus sinensis 60000.0 1 * -3.2.1.26 * clostridium perfringens 37000.0 1 PMID:9145517 -3.2.1.26 * corynebacterium glutamicum 92000.0 1 * -3.2.1.26 * corynebacterium murisepticum 70000.0 1 PMID:8406545 -3.2.1.26 * cyberlindnera jadinii 300000.0 8 PMID:11825607;PMID:9165761 -3.2.1.26 * daucus carota 504000.0 4 PMID:8972597 -3.2.1.26 * elsholtzia haichowensis 750800.0 5 PMID:26123289 -3.2.1.26 * escherichia coli 125000.0 1 * -3.2.1.26 * fusarium oxysporum 295000.0 6 * -3.2.1.26 * fusarium solani 65000.0 1 PMID:16787006 -3.2.1.26 * glycine max 240000.0 2 PMID:1575518 -3.2.1.26 * helianthus tuberosus 58000.0 1 * -3.2.1.26 * hordeum vulgare 155000.0 3 PMID:8310063 -3.2.1.26 * ipomoea batatas 72000.0 2 PMID:12460425;PMID:12590504 -3.2.1.26 * kluyveromyces marxianus 56000.0 1 * -3.2.1.26 * lathyrus oleraceus 69000.0 4 PMID:20590984;PMID:21923131 -3.2.1.26 * lilium auratum 450000.0 1 PMID:16663453 -3.2.1.26 * lilium longiflorum 750000.0 1 * -3.2.1.26 * limosilactobacillus reuteri 58000.0 1 PMID:28731585 -3.2.1.26 * malus domestica 220000.0 2 * -3.2.1.26 * mangifera indica 140000.0 2 * -3.2.1.26 * manihot esculenta 73500.0 3 PMID:24838076 -3.2.1.26 * metarhizium robertsii 63900.0 1 PMID:24205119 -3.2.1.26 * meyerozyma guilliermondii 70000.0 1 * -3.2.1.26 * neurospora crassa 210000.0 1 PMID:5539234 -3.2.1.26 * nicotiana glauca 89100.0 1 * -3.2.1.26 * nicotiana tabacum 76000.0 3 PMID:16667892 -3.2.1.26 * oryza sativa 66000.0 2 PMID:12882270;PMID:18317796 -3.2.1.26 * paecilomyces variotii 210000.0 1 PMID:22806841 -3.2.1.26 * penicillium citreonigrum 43000.0 1 PMID:36579491 -3.2.1.26 * penicillium janczewskii 80000.0 1 * -3.2.1.26 * phaffia rhodozyma 200000.0 4 PMID:19088319 -3.2.1.26 * phyllostachys edulis 240000.0 4 * -3.2.1.26 * portulaca oleracea 62000.0 1 * -3.2.1.26 * prunus persica 120000.0 2 * -3.2.1.26 * pseudomonas fluorescens 35400.0 1 * -3.2.1.26 * pyrus pyrifolia 80000.0 2 PMID:12711132 -3.2.1.26 * raphanus sativus 48500.0 1 * -3.2.1.26 * rhodotorula glutinis 100000.0 3 PMID:12423880 -3.2.1.26 * ricinus communis 78000.0 2 PMID:3988740 -3.2.1.26 * saccharomyces cerevisiae 1070000.0 24 PMID:11115390;PMID:11693382;PMID:2187435;PMID:21906653;PMID:23104410;PMID:23430743;PMID:24938994;PMID:3902817;PMID:4963242;PMID:4967422;PMID:5647272;PMID:6772225 -3.2.1.26 * saccharum officinarum 380000.0 3 PMID:19091583 -3.2.1.26 * schizosaccharomyces pombe 205000.0 2 PMID:2187435 -3.2.1.26 * schwanniomyces occidentalis 165000.0 5 PMID:17904238;PMID:19923741 -3.2.1.26 * solanum lycopersicum 79000.0 7 PMID:18573306;PMID:22105847;PMID:24374160 -3.2.1.26 * solanum tuberosum 70000.0 1 * -3.2.1.26 * termitomyces clypeatus 13500.0 1 * -3.2.1.26 * thermotoga neapolitana 47000.0 2 PMID:19125220 -3.2.1.26 * trametes sanguinea 84000.0 2 PMID:7669814 -3.2.1.26 * triticum aestivum 158000.0 2 PMID:16664223 -3.2.1.26 * tropaeolum majus 74000.0 1 * -3.2.1.26 * uncultured bacterium 66700.0 5 PMID:23638032 -3.2.1.26 * uromyces viciae-fabae 84300.0 1 PMID:16776296 -3.2.1.26 * vitis vinifera 71000.0 1 PMID:19298882 -3.2.1.26 * wickerhamomyces anomalus 101000.0 1 PMID:29312954 -3.2.1.26 * woodfordia fruticosa 280000.0 4 PMID:22905381 -3.2.1.26 * zymomonas mobilis 78000.0 11 PMID:18303841;PMID:18712547;PMID:26777250;PMID:28731585 -3.2.1.28 * amanita muscaria 165000.0 2 * -3.2.1.28 * apis mellifera 76000.0 7 PMID:1144;PMID:11826961;PMID:17827701 -3.2.1.28 * arabidopsis thaliana 80000.0 1 PMID:17673210 -3.2.1.28 * ascaris suum 76000.0 2 PMID:12941639 -3.2.1.28 * beauveria bassiana 84400.0 2 PMID:20630729 -3.2.1.28 * blastobotrys adeninivorans 250000.0 1 * -3.2.1.28 * bombyx mori 140000.0 6 PMID:18492231;PMID:20870456;PMID:20965194 -3.2.1.28 * candida albicans 104000.0 1 PMID:27133444 -3.2.1.28 * chironomus riparius 67000.0 1 PMID:20542873 -3.2.1.28 * cicer arietinum 223000.0 2 * -3.2.1.28 * cyberlindnera jadinii 175000.0 2 PMID:22484163;PMID:2411719 -3.2.1.28 * dictyostelium discoideum 105000.0 3 PMID:16139441;PMID:6847202 -3.2.1.28 * enterobacter cloacae 65000.0 1 PMID:29412176;PMID:30657252 -3.2.1.28 * escherichia coli 74000.0 4 PMID:25179874;PMID:8892826 -3.2.1.28 * fusarium oxysporum 120000.0 2 PMID:17512710 -3.2.1.28 * halorhodospira halochloris 480000.0 1 * -3.2.1.28 * helicoverpa armigera 71000.0 3 PMID:17319935;PMID:29412176;PMID:29912409;PMID:30657252 -3.2.1.28 * holothuria leucospilota 67950.0 1 PMID:29719214 -3.2.1.28 * lentinula edodes 158000.0 1 * -3.2.1.28 * lobosphaera sp. 400000.0 1 PMID:7765274 -3.2.1.28 * medicago sativa 120000.0 1 * -3.2.1.28 * metarhizium anisopliae 170000.0 4 PMID:16980715;PMID:17419071 -3.2.1.28 * mycolicibacterium smegmatis 71000.0 1 PMID:17319935;PMID:29912409 -3.2.1.28 * mycothermus thermophilus 392000.0 2 PMID:8980633 -3.2.1.28 * neurospora crassa 437000.0 4 PMID:10564806;PMID:19073263 -3.2.1.28 * nostoc punctiforme 52000.0 1 PMID:19436130 -3.2.1.28 * oryctolagus cuniculus 175000.0 9 PMID:22484163;PMID:2411719;PMID:3697377;PMID:3828380;PMID:6466686 -3.2.1.28 * phaseolus vulgaris 45000.0 2 PMID:15907687 -3.2.1.28 * phycomyces blakesleeanus 210000.0 1 PMID:1138912 -3.2.1.28 * rattus norvegicus 240000.0 4 PMID:18444;PMID:240424 -3.2.1.28 * rhizopus microsporus var. rhizopodiformis 105000.0 3 PMID:16139441;PMID:6847202 -3.2.1.28 * rhodothermus marinus 77000.0 3 PMID:16944251 -3.2.1.28 * rhynchosciara americana 122000.0 1 PMID:656440 -3.2.1.28 * saccharomyces cerevisiae 218000.0 8 PMID:19703229;PMID:3024571;PMID:3286651;PMID:6430270;PMID:8764988 -3.2.1.28 * spodoptera exigua 74000.0 2 PMID:18492231;PMID:20405036;PMID:20965194 -3.2.1.28 * spodoptera frugiperda 67000.0 2 PMID:15475303;PMID:19843188 -3.2.1.28 * spodoptera litura 73620.0 2 PMID:23613237 -3.2.1.28 * sulfolobus acidocaldarius 63600.0 1 PMID:29642287 -3.2.1.28 * sus scrofa 80000.0 1 PMID:3592657 -3.2.1.28 * tenebrio molitor 58000.0 1 PMID:23770497 -3.2.1.28 * thermochaetoides thermophila 200000.0 2 * -3.2.1.28 * thermomyces lanuginosus 170000.0 2 PMID:10564806;PMID:356886 -3.2.1.28 * trichocladium griseum 580000.0 3 PMID:2223824 -3.2.1.28 * trichoderma reesei 88000.0 1 PMID:31976 -3.2.1.28 * zunongwangia sp. 61300.0 1 PMID:26822136 -3.2.1.3 * acremonium charticola 69000.0 1 PMID:16350024 -3.2.1.3 * agroathelia rolfsii 79000.0 9 PMID:9802217 -3.2.1.3 * arthrobotrys conoides 87000.0 1 * -3.2.1.3 * aspergillus awamori 88000.0 12 PMID:11150611;PMID:20131079;PMID:6434506;PMID:9056481 -3.2.1.3 * aspergillus candidus 75000.0 3 PMID:6434506 -3.2.1.3 * aspergillus coreanus 91000.0 4 * -3.2.1.3 * aspergillus flavus 63000.0 1 * -3.2.1.3 * aspergillus foetidus 78000.0 4 PMID:6434506 -3.2.1.3 * aspergillus fumigatus 42000.0 2 PMID:19708824 -3.2.1.3 * aspergillus japonicus 72000.0 1 PMID:28412339 -3.2.1.3 * aspergillus niger 125000.0 15 PMID:16091302;PMID:18378674;PMID:21301084;PMID:24837950 -3.2.1.3 * aspergillus niveus 77000.0 2 PMID:19697071 -3.2.1.3 * aspergillus oryzae 81000.0 7 PMID:19708824;PMID:6434506 -3.2.1.3 * aspergillus phoenicis 90000.0 3 PMID:6434506;PMID:6783630;PMID:6796572 -3.2.1.3 * aspergillus sp. 76000.0 1 PMID:19708824 -3.2.1.3 * aureobasidium pullulans 98000.0 4 PMID:15948964;PMID:16488199;PMID:17823796 -3.2.1.3 * beta vulgaris 91000.0 2 PMID:16666261 -3.2.1.3 * blastobotrys adeninivorans 225000.0 1 * -3.2.1.3 * caldanaerobacter subterraneus subsp. tengcongensis mb4 77000.0 1 PMID:20155355 -3.2.1.3 * camelus dromedarius 58000.0 1 PMID:15621512 -3.2.1.3 * cephalosporium eichhorniae 26850.0 2 PMID:19708824;PMID:23338146 -3.2.1.3 * clostridium thermoamylolyticum 79920.0 2 * -3.2.1.3 * coniophora cerebella 48000.0 1 PMID:6434506 -3.2.1.3 * curvularia lunata 66000.0 2 PMID:15948964;PMID:16488199;PMID:17823796;PMID:19708824 -3.2.1.3 * endomyces sp. 55000.0 1 PMID:6434506 -3.2.1.3 * endomycopsis fibuligera 58000.0 2 PMID:15621512;PMID:19708824 -3.2.1.3 * endophytic fungus ef6 62200.0 3 PMID:21950121 -3.2.1.3 * fusarium solani 41000.0 3 PMID:19708824 -3.2.1.3 * gymnascella citrina 88000.0 2 * -3.2.1.3 * halolactibacillus sp. sk71 78500.0 1 PMID:25138675 -3.2.1.3 * homo sapiens 105360.0 1 PMID:16817895 -3.2.1.3 * humicola sp. 72800.0 1 * -3.2.1.3 * lactobacillus amylovorus 47000.0 1 PMID:19708824 -3.2.1.3 * lipomyces kononenkoae 230000.0 4 * -3.2.1.3 * meretrix lusoria 100000.0 1 * -3.2.1.3 * moesziomyces antarcticus 48500.0 3 PMID:19708824;PMID:3106037 -3.2.1.3 * monascus purpureus 89000.0 2 PMID:17928688 -3.2.1.3 * monascus sp. (in: ascomycete fungi) 54000.0 4 * -3.2.1.3 * mucor javanicus 61000.0 1 PMID:19708824 -3.2.1.3 * mucor rouxianus 59000.0 4 PMID:6434506 -3.2.1.3 * mycothermus thermophilus 75000.0 2 PMID:11501467;PMID:14665735;PMID:24031228 -3.2.1.3 * myrothecium sp. 96000.0 2 * -3.2.1.3 * neurospora crassa 82000.0 2 PMID:19708824 -3.2.1.3 * paecilomyces variotii 86500.0 2 PMID:16350024;PMID:17938981 -3.2.1.3 * paenibacillus amylolyticus 66000.0 1 PMID:30681161 -3.2.1.3 * penaeus japonicus 105000.0 1 PMID:20509216 -3.2.1.3 * penicillium oxalicum 86000.0 3 PMID:27777618 -3.2.1.3 * picrophilus oshimae 292000.0 7 PMID:12448707 -3.2.1.3 * pseudozyma tsukubaensis 56000.0 1 PMID:3937490 -3.2.1.3 * rana japonica 550000.0 4 PMID:8814221 -3.2.1.3 * rasamsonia emersonii 70000.0 2 PMID:12356463 -3.2.1.3 * rhizopus arrhizus 100000.0 7 PMID:6434506 -3.2.1.3 * rhizopus sp. 74000.0 3 PMID:32172 -3.2.1.3 * saccharolobus solfataricus 65000.0 1 PMID:19708824 -3.2.1.3 * saccharomyces cerevisiae 306000.0 7 PMID:15116339;PMID:19708824;PMID:2493265;PMID:3124820 -3.2.1.3 * saccharomycopsis fibuligera 57000.0 3 PMID:19708824 -3.2.1.3 * sclerotinia sclerotiorum 72000.0 1 PMID:11989765 -3.2.1.3 * thermoactinomyces vulgaris 155000.0 1 PMID:16511025 -3.2.1.3 * thermoanaerobacterium thermosaccharolyticum 77000.0 4 PMID:12614608;PMID:16348541;PMID:19708824 -3.2.1.3 * thermochaetoides thermophila 66000.0 4 PMID:16107755;PMID:18045411;PMID:19708824 -3.2.1.3 * thermomucor indicae-seudaticae 45000.0 3 PMID:12790660;PMID:19484200;PMID:19708824 -3.2.1.3 * thermomyces lanuginosus 66000.0 3 PMID:15948964;PMID:16488199;PMID:17823796;PMID:6796044 -3.2.1.3 * thermoplasma acidophilum 141000.0 4 PMID:12448707;PMID:18080814 -3.2.1.3 * thermothielavioides terrestris 75000.0 2 PMID:11501467;PMID:14665735 -3.2.1.3 * thielaviopsis paradoxa 77000.0 1 PMID:19708824 -3.2.1.3 * trichoderma harzianum 66000.0 1 PMID:15948964;PMID:16488199;PMID:17823796 -3.2.1.3 * trichoderma reesei 66000.0 1 PMID:19708824 -3.2.1.3 * tricholoma matsutake 63900.0 1 PMID:30122147 -3.2.1.31 * arabidopsis thaliana 55000.0 1 PMID:18667448 -3.2.1.31 * aspergillus niger 85700.0 4 PMID:11423108;PMID:18377882 -3.2.1.31 * aspergillus oryzae 290000.0 1 PMID:29146597 -3.2.1.31 * bos taurus 160000.0 1 PMID:16774908 -3.2.1.31 * escherichia coli 290000.0 2 PMID:8845801 -3.2.1.31 * homo sapiens 390000.0 7 PMID:18268347;PMID:413568;PMID:6416296;PMID:7305955;PMID:7421244;PMID:8053907 -3.2.1.31 * levilactobacillus brevis 71000.0 1 PMID:20075633 -3.2.1.31 * littorina littorea 310000.0 2 PMID:428383 -3.2.1.31 * mus musculus 310000.0 2 PMID:1194264;PMID:237911;PMID:623478 -3.2.1.31 * neurospora crassa 90100.0 2 PMID:18377882 -3.2.1.31 * oryctolagus cuniculus 310000.0 4 PMID:2108135;PMID:4215418 -3.2.1.31 * pomacea sp. 180000.0 2 PMID:16522172 -3.2.1.31 * protubera nipponica 70000.0 1 PMID:6530397 -3.2.1.31 * rattus norvegicus 310000.0 4 PMID:1141228;PMID:15358052;PMID:236293;PMID:413568;PMID:6416296;PMID:64358;PMID:7305955;PMID:7421244;PMID:8108 -3.2.1.31 * saccharolobus solfataricus 66800.0 1 PMID:22234844 -3.2.1.31 * streptococcus sp. 140000.0 2 * -3.2.1.31 * sus scrofa 310000.0 1 PMID:413568;PMID:6416296;PMID:7305955;PMID:7421244 -3.2.1.31 * thermotoga maritima 66000.0 1 PMID:16303119 -3.2.1.32 * alcaligenes sp. 59000.0 1 PMID:12501421 -3.2.1.32 * bacillus subtilis 340000.0 2 PMID:11861085 -3.2.1.32 * brevundimonas vesicularis 91000.0 2 * -3.2.1.32 * flammeovirga pacifica 40510.0 1 PMID:30021136 -3.2.1.32 * pseudomonas sp. 36000.0 2 PMID:1368551 -3.2.1.32 * psychroflexus torquis 63000.0 1 PMID:25214227 -3.2.1.32 * thermotoga neapolitana 38033.0 2 PMID:23149756 -3.2.1.32 * vibrio sp. 53000.0 3 PMID:10635569;PMID:21519808 -3.2.1.33 * bos taurus 190000.0 1 PMID:11530024 -3.2.1.33 * gallus gallus 166000.0 1 PMID:290488 -3.2.1.33 * homo sapiens 172600.0 1 PMID:1374391 -3.2.1.33 * oryctolagus cuniculus 279000.0 15 PMID:1063726;PMID:1122910;PMID:1170897;PMID:4415480;PMID:4633324;PMID:5086952;PMID:6232392;PMID:8215409 -3.2.1.33 * rattus norvegicus 160000.0 1 PMID:15180797 -3.2.1.33 * saccharolobus solfataricus 355000.0 6 * -3.2.1.33 * saccharomyces cerevisiae 640000.0 8 PMID:24491554;PMID:4335607;PMID:4577202;PMID:5424210 -3.2.1.33 * squalus acanthias 162000.0 2 PMID:13809 -3.2.1.33 * sus scrofa 170000.0 1 PMID:16636458 -3.2.1.35 * agkistrodon contortrix contortrix 61000.0 2 PMID:11368337 -3.2.1.35 * bos grunniens 55000.0 1 * -3.2.1.35 * bothrops atrox 69000.0 2 PMID:30946947;PMID:35853550 -3.2.1.35 * bungarus caeruleus 14000.0 1 * -3.2.1.35 * caenorhabditis elegans 80000.0 1 PMID:18390555 -3.2.1.35 * chersonesometrus fulvipes 82000.0 1 PMID:2317213 -3.2.1.35 * chrysops viduatus 50000.0 1 PMID:18820742 -3.2.1.35 * crotalus durissus terrificus 64500.0 1 PMID:22940594 -3.2.1.35 * ctenocephalides felis 52000.0 1 PMID:18820742 -3.2.1.35 * culicoides kibunensis 70000.0 2 PMID:18820742 -3.2.1.35 * eusimulium latipes 40000.0 1 PMID:18820742 -3.2.1.35 * hippasa partita 42260.0 1 PMID:17548101 -3.2.1.35 * homo sapiens 130000.0 10 PMID:11341771;PMID:16713680;PMID:17227790;PMID:17503783;PMID:21740893;PMID:2331294;PMID:9018429 -3.2.1.35 * lachesis muta rhombeata 60000.0 1 PMID:35853550 -3.2.1.35 * loxosceles intermedia 45000.0 1 PMID:23658852 -3.2.1.35 * macaca sp. 64000.0 1 PMID:11868814 -3.2.1.35 * mus musculus 180000.0 10 PMID:12944181;PMID:19605784;PMID:20586096;PMID:33345310;PMID:35853550;PMID:7794889 -3.2.1.35 * naja naja 74000.0 5 PMID:15134834;PMID:16038614;PMID:16212553 -3.2.1.35 * nephrops norvegicus 320000.0 1 * -3.2.1.35 * olivierus martensii 48700.0 2 PMID:18611448 -3.2.1.35 * ovis aries aries 70000.0 1 * -3.2.1.35 * palamneus gravimanus 52000.0 1 PMID:16359718 -3.2.1.35 * phlebotomus papatasi 70000.0 1 PMID:18820742 -3.2.1.35 * potamotrygon motoro 79000.0 1 PMID:18346772 -3.2.1.35 * rattus norvegicus 73000.0 2 PMID:19783662;PMID:19915162 -3.2.1.35 * simulium ornatum 40000.0 1 PMID:18820742 -3.2.1.35 * streptococcus dysgalactiae 55000.0 1 PMID:16713680;PMID:2331294 -3.2.1.35 * sus scrofa 80000.0 4 PMID:17881045 -3.2.1.35 * synanceia horrida 62000.0 1 PMID:1499262 -3.2.1.35 * synanceia verrucosa 59000.0 1 PMID:21820461 -3.2.1.35 * talaromyces purpureogenus 31700.0 2 PMID:21094645 -3.2.1.35 * tityus serrulatus 50000.0 2 PMID:24551256 -3.2.1.36 * bacillus sp. (in: firmicutes) 120000.0 1 PMID:24736576 -3.2.1.36 * chrysops caecutiens 48000.0 1 PMID:27045753 -3.2.1.36 * chrysops relictus 40000.0 1 PMID:27045753 -3.2.1.36 * chrysops viduatus 52000.0 1 PMID:27045753 -3.2.1.36 * haematopota pluvialis 40000.0 1 PMID:27045753 -3.2.1.36 * hybomitra ciureai 37000.0 1 PMID:27045753 -3.2.1.36 * hybomitra muehlfeldi 35000.0 1 PMID:27045753 -3.2.1.36 * streptococcus agalactiae 116000.0 1 PMID:8061410 -3.2.1.36 * streptococcus equi subsp. zooepidemicus 55000.0 1 PMID:2331294 -3.2.1.36 * streptococcus equinus 55000.0 1 PMID:2331294 -3.2.1.36 * tabanus autumnalis 38000.0 1 PMID:27045753 -3.2.1.36 * tabanus maculicornis 48000.0 1 PMID:27045753 -3.2.1.36 * vespa tropica 39572.0 2 PMID:27790249 -3.2.1.37 * agroathelia rolfsii 180000.0 1 * -3.2.1.37 * anoxybacillus sp. 3m 140000.0 1 PMID:30219517 -3.2.1.37 * arabidopsis thaliana 67000.0 2 PMID:15181203 -3.2.1.37 * aspergillus awamori 115000.0 3 PMID:16202538;PMID:9872754 -3.2.1.37 * aspergillus fumigatus 360000.0 2 * -3.2.1.37 * aspergillus nidulans 240000.0 3 PMID:15628881 -3.2.1.37 * aspergillus niger 253000.0 5 PMID:11722900;PMID:29174354;PMID:29728961;PMID:6434508 -3.2.1.37 * aspergillus oryzae 110000.0 2 PMID:20129093;PMID:9872754 -3.2.1.37 * aspergillus sp. 250000.0 2 PMID:12559729 -3.2.1.37 * aspergillus versicolor 100000.0 2 * -3.2.1.37 * aureobasidium melanogenum 88500.0 2 PMID:20547381 -3.2.1.37 * aureobasidium pullulans 224000.0 3 PMID:28918541 -3.2.1.37 * bacillus pumilus 190000.0 1 PMID:1765080 -3.2.1.37 * bacillus subtilis 66000.0 1 * -3.2.1.37 * bifidobacterium adolescentis 87000.0 3 PMID:20971079 -3.2.1.37 * bifidobacterium breve 55700.0 2 PMID:12913270;PMID:22534302 -3.2.1.37 * blastobotrys adeninivorans 160000.0 2 PMID:1512706 -3.2.1.37 * caldicellulosiruptor saccharolyticus 65400.0 1 PMID:18378602 -3.2.1.37 * ceratocystis fimbriata 161600.0 1 * -3.2.1.37 * cucumis sativus 68000.0 1 * -3.2.1.37 * cyberlindnera jadinii 120000.0 2 PMID:11330664 -3.2.1.37 * dictyoglomus thermophilum 55000.0 1 PMID:30176709 -3.2.1.37 * enterobacter ludwigii 61290.0 1 * -3.2.1.37 * fusarium proliferatum 91200.0 1 PMID:12835054 -3.2.1.37 * geobacillus stearothermophilus 180000.0 5 PMID:14993701;PMID:15142626;PMID:15272177;PMID:15628881;PMID:2123854 -3.2.1.37 * geobacillus thermoleovorans 61500.0 2 PMID:18007043;PMID:18815904 -3.2.1.37 * irpex lacteus 365400.0 2 PMID:30138852 -3.2.1.37 * levilactobacillus brevis 330000.0 2 PMID:19702863 -3.2.1.37 * malbranchea pulchella var. sulfurea 26000.0 1 * -3.2.1.37 * mycothermus thermophilus 92200.0 4 * -3.2.1.37 * neocallimastix frontalis 180000.0 2 PMID:2126511 -3.2.1.37 * neurospora crassa 83000.0 1 PMID:18555300 -3.2.1.37 * paenibacillus curdlanolyticus 39000.0 1 * -3.2.1.37 * paenibacillus terrae 65000.0 1 * -3.2.1.37 * parageobacillus thermantarcticus 150000.0 2 PMID:15142626;PMID:2123854 -3.2.1.37 * penicillium wortmanni 210000.0 8 PMID:752411 -3.2.1.37 * phlebia radiata 27000.0 1 PMID:11720306 -3.2.1.37 * pomacea canaliculata 96000.0 1 PMID:9063971 -3.2.1.37 * rasamsonia emersonii 181000.0 2 * -3.2.1.37 * rhizophlyctis rosea 39000.0 1 PMID:30397764 -3.2.1.37 * ruminiclostridium cellulolyticum 43000.0 1 PMID:7574661 -3.2.1.37 * saccharolobus solfataricus 338800.0 2 PMID:17033733 -3.2.1.37 * saccharum officinarum 62000.0 1 PMID:6819293 -3.2.1.37 * streptomyces sp. 173000.0 2 * -3.2.1.37 * streptomyces thermoviolaceus 83000.0 3 PMID:11577723;PMID:20606274 -3.2.1.37 * talaromyces amestolkiae 200000.0 1 PMID:14659747;PMID:26150469 -3.2.1.37 * talaromyces purpureogenus 50700.0 5 PMID:20562284 -3.2.1.37 * termitomyces clypeatus 94000.0 1 * -3.2.1.37 * thermoanaerobacter ethanolicus 165000.0 2 PMID:1522062 -3.2.1.37 * thermoanaerobacterium saccharolyticum 210000.0 9 PMID:12146939;PMID:14659747;PMID:21131522;PMID:26150469 -3.2.1.37 * thermoanaerobacterium thermosaccharolyticum 245000.0 1 * -3.2.1.37 * thermobifida fusca 168000.0 2 * -3.2.1.37 * thermobifida halotolerans 61500.0 1 PMID:30225545 -3.2.1.37 * thermothelomyces heterothallicus 45000.0 1 * -3.2.1.37 * thermotoga petrophila 86700.0 1 PMID:30616097 -3.2.1.37 * trichocladium griseum 50000.0 2 * -3.2.1.37 * trichoderma koningii 105000.0 1 * -3.2.1.37 * trichoderma reesei 100000.0 3 * -3.2.1.37 * trichoderma sp. 80000.0 1 * -3.2.1.37 * trichoderma viride 102000.0 3 * -3.2.1.37 * uncultured bacterium 42000.0 1 PMID:21720773 -3.2.1.37 * uncultured rumen bacterium 80000.0 1 PMID:22085266 -3.2.1.37 * zea mays 68500.0 1 * -3.2.1.38 * achatina balteata 360000.0 5 PMID:718956 -3.2.1.38 * asclepias curassavica 51000.0 1 * -3.2.1.38 * aspergillus phoenicis 57000.0 1 PMID:1524431 -3.2.1.38 * bifidobacterium breve clb 48000.0 1 PMID:9063964 -3.2.1.38 * citrobacter sp. 775000.0 2 PMID:15993389 -3.2.1.38 * dalbergia cochinchinensis 66000.0 1 PMID:8830058 -3.2.1.38 * haloferax volcanii 180000.0 2 PMID:9048905 -3.2.1.38 * lactuca sativa 37000.0 1 PMID:3409886 -3.2.1.38 * shewanella sp. 50000.0 1 PMID:23497058 -3.2.1.39 * acetivibrio thermocellus 148000.0 2 PMID:12686644 -3.2.1.39 * agaricus bisporus 33700.0 1 PMID:9922471 -3.2.1.39 * agaricus brasiliensis 33000.0 1 * -3.2.1.39 * apium graveolens 35000.0 1 PMID:16666646 -3.2.1.39 * aplysia kurodai 36000.0 1 PMID:19883786;PMID:23560994 -3.2.1.39 * arthrobacter sp. 79760.0 3 PMID:17587693;PMID:3096974 -3.2.1.39 * aspergillus fumigatus 150000.0 3 PMID:20619350;PMID:9030754 -3.2.1.39 * aspergillus nidulans 230000.0 2 PMID:20602653 -3.2.1.39 * atriplex littoralis 26000.0 2 * -3.2.1.39 * bacillus amyloliquefaciens 27790.0 1 PMID:23108702 -3.2.1.39 * bacillus sp. (in: firmicutes) 40000.0 2 PMID:16666646;PMID:16946451 -3.2.1.39 * boscia senegalensis 36000.0 1 PMID:11563825 -3.2.1.39 * candida albicans 124157.0 1 PMID:16328626 -3.2.1.39 * cellulosimicrobium cellulans 43000.0 4 PMID:11676595;PMID:16946451;PMID:21979581 -3.2.1.39 * chlamys albidus 37000.0 1 PMID:19026410 -3.2.1.39 * citrus x aurantiifolia 12000.0 1 * -3.2.1.39 * coprinopsis cinerea 45000.0 1 PMID:26199012 -3.2.1.39 * cryptopygus antarcticus 46000.0 2 PMID:20079869 -3.2.1.39 * delftia tsuruhatensis 29000.0 1 PMID:21169426 -3.2.1.39 * euglena gracilis 66000.0 3 PMID:26028521;PMID:36586565 -3.2.1.39 * flavobacterium dormitator 20000.0 1 * -3.2.1.39 * flavobacterium sp. 16000.0 1 PMID:4776863 -3.2.1.39 * fraxinus excelsior 47760.0 2 PMID:26177095 -3.2.1.39 * fungi imperfecti 24500.0 1 * -3.2.1.39 * gecarcoidea natalis 71000.0 2 PMID:18587122 -3.2.1.39 * glycine max 33000.0 1 PMID:16662849 -3.2.1.39 * haliotis discus hannai 36866.0 2 PMID:19446649 -3.2.1.39 * haliotis tuberculata 60000.0 1 PMID:9821264 -3.2.1.39 * hevea brasiliensis 35000.0 2 * -3.2.1.39 * hordeum vulgare 33000.0 2 PMID:12023973;PMID:21146160;PMID:8424790 -3.2.1.39 * lathyrus oleraceus 34300.0 2 PMID:16666142 -3.2.1.39 * lentinula edodes 26000.0 2 PMID:21965406 -3.2.1.39 * littorina kurila 40000.0 2 PMID:18675406 -3.2.1.39 * malus domestica 20000.0 1 PMID:12765782 -3.2.1.39 * mizuhopecten yessoensis 36900.0 2 * -3.2.1.39 * musa acuminata 30000.0 1 PMID:10672030 -3.2.1.39 * musa x paradisiaca 37000.0 1 PMID:19697038 -3.2.1.39 * niallia circulans 40000.0 1 PMID:4310 -3.2.1.39 * nicotiana glutinosa 45000.0 1 PMID:5061994 -3.2.1.39 * nicotiana tabacum 33000.0 1 * -3.2.1.39 * oryza sativa 29000.0 1 PMID:9076936 -3.2.1.39 * paenibacillus sp. 44000.0 1 PMID:12764561 -3.2.1.39 * penicillium italicum 68000.0 1 * -3.2.1.39 * perna viridis 33000.0 1 PMID:12023973;PMID:21146160 -3.2.1.39 * pneumocystis carinii 105000.0 3 PMID:19783787;PMID:25231017 -3.2.1.39 * pneumocystis murina 105000.0 2 PMID:25231017 -3.2.1.39 * porodisculus pendulus 43000.0 1 * -3.2.1.39 * prunus avium 20000.0 1 PMID:12765782 -3.2.1.39 * pseudocardium sachalinense 38000.0 1 PMID:14990213 -3.2.1.39 * pseudomonas aeruginosa 83400.0 1 PMID:29108625 -3.2.1.39 * pyrococcus furiosus 30135.0 1 PMID:19913513 -3.2.1.39 * rhizoctonia solani 62000.0 4 PMID:19022284 -3.2.1.39 * rhizopus microsporus var. chinensis 23000.0 1 * -3.2.1.39 * saccharomyces cerevisiae 218000.0 4 PMID:6358190;PMID:8458852 -3.2.1.39 * schizophyllum commune 35500.0 1 * -3.2.1.39 * schizosaccharomyces pombe 160500.0 4 PMID:7275933 -3.2.1.39 * sclerotium glucanicum 85000.0 1 PMID:1627595 -3.2.1.39 * secale cereale 24300.0 1 * -3.2.1.39 * shouchella clausii 71000.0 1 PMID:16233365 -3.2.1.39 * solanum lycopersicum 35000.0 2 PMID:10944151;PMID:16666646 -3.2.1.39 * solanum tuberosum 36500.0 1 PMID:25800964 -3.2.1.39 * spodoptera frugiperda 40400.0 1 PMID:20816775 -3.2.1.39 * stachybotrys elegans 79000.0 1 PMID:9933916 -3.2.1.39 * streptomyces sioyaensis 49000.0 1 PMID:11932459 -3.2.1.39 * streptomyces sp. 42700.0 3 PMID:19697016;PMID:19883786;PMID:23560994 -3.2.1.39 * streptomyces sp. 9x166 80000.0 1 PMID:26888054 -3.2.1.39 * tenebrio molitor 50000.0 2 PMID:19840850 -3.2.1.39 * trichoderma harzianum 74000.0 4 PMID:11499921;PMID:7592488 -3.2.1.39 * trichoderma koningii 75000.0 1 PMID:16450064 -3.2.1.39 * trichoderma reesei 24000.0 1 * -3.2.1.39 * trichoderma viride 34700.0 1 * -3.2.1.39 * triticum aestivum 32980.0 8 PMID:17110121;PMID:19757158 -3.2.1.4 * [eubacterium] cellulosolvens 127047.0 1 PMID:16204489 -3.2.1.4 * acetivibrio thermocellus 110000.0 12 * -3.2.1.4 * actinomyces sp. 40 57100.0 2 PMID:26732336 -3.2.1.4 * agroathelia rolfsii 78000.0 5 * -3.2.1.4 * alicyclobacillus vulcanalis 98466.0 1 PMID:25722023 -3.2.1.4 * aquifex aeolicus 38831.0 2 PMID:11118302 -3.2.1.4 * artemia salina 96000.0 1 PMID:24291747 -3.2.1.4 * aspergillus aculeatus 45000.0 1 PMID:17685540;PMID:2500422 -3.2.1.4 * aspergillus flavus 55000.0 1 PMID:18576142;PMID:31297753;PMID:34988069 -3.2.1.4 * aspergillus fumigatus 88000.0 1 PMID:37216583 -3.2.1.4 * aspergillus niger 55000.0 5 PMID:18083533;PMID:19015;PMID:25331339;PMID:33319112 -3.2.1.4 * aspergillus oryzae 41500.0 3 PMID:18704277;PMID:35124880 -3.2.1.4 * bacillus amyloliquefaciens 55118.0 2 PMID:17320379;PMID:20381456 -3.2.1.4 * bacillus cellulyticus k-12 65000.0 2 PMID:15304785 -3.2.1.4 * bacillus licheniformis 54400.0 1 PMID:35192092 -3.2.1.4 * bacillus mycoides 62000.0 1 PMID:22012583;PMID:23070713 -3.2.1.4 * bacillus pumilus 40000.0 1 PMID:15973054;PMID:24657377;PMID:25387612 -3.2.1.4 * bacillus sp. (in: firmicutes) 92000.0 6 PMID:15834791;PMID:15973054;PMID:18473955;PMID:22012583;PMID:23070713;PMID:24657377;PMID:25387612;PMID:25886936 -3.2.1.4 * bacillus subtilis 439000.0 18 PMID:18576142;PMID:18587122;PMID:18632263;PMID:19050861;PMID:19366617;PMID:19669599;PMID:22610115;PMID:23379273;PMID:31297753;PMID:32140794;PMID:34409950;PMID:34988069;PMID:35717508;PMID:37940165;PMID:7710279 -3.2.1.4 * bacillus vallismortis 80000.0 1 PMID:15834791;PMID:25886936 -3.2.1.4 * bacillus velezensis 18000.0 1 PMID:36600152 -3.2.1.4 * batocera horsfieldi 33000.0 2 PMID:23201420 -3.2.1.4 * beltraniella portoricensis 40000.0 1 PMID:15973054;PMID:24657377;PMID:25387612 -3.2.1.4 * bispora sp. mey-1 48000.0 1 PMID:19590866 -3.2.1.4 * bursaphelenchus xylophilus 252000.0 10 PMID:18460801 -3.2.1.4 * caecomyces sp. cr4 95000.0 3 PMID:18791765 -3.2.1.4 * caldicellulosiruptor saccharolyticus 120000.0 1 PMID:2126700 -3.2.1.4 * catharanthus roseus 96000.0 2 * -3.2.1.4 * cellulomonas fimi 46700.0 1 PMID:20136145 -3.2.1.4 * cellulomonas flavigena 96798.0 1 PMID:17985078 -3.2.1.4 * cellulomonas sp. 36000.0 1 PMID:8978089 -3.2.1.4 * cherax destructor 53000.0 4 PMID:18587122;PMID:34409950 -3.2.1.4 * chrysosporium lucknowense 60000.0 6 PMID:15193129 -3.2.1.4 * cohnella sp. a01 56860.0 2 PMID:32140794;PMID:35717508 -3.2.1.4 * coniophora cerebella 42000.0 2 * -3.2.1.4 * coptotermes formosanus 48160.0 2 PMID:19364531 -3.2.1.4 * corbicula japonica 180000.0 8 PMID:18436461 -3.2.1.4 * cryptococcus neoformans 45000.0 1 PMID:32246714 -3.2.1.4 * cryptococcus sp. s-2 34070.0 2 PMID:18479937 -3.2.1.4 * desulfurococcaceae archaeon ebi-244 94000.0 1 PMID:21730956 -3.2.1.4 * dickeya chrysanthemi 45000.0 2 * -3.2.1.4 * dictyoglomus turgidum 43000.0 1 PMID:29177717 -3.2.1.4 * dolabella auricularia 44000.0 1 PMID:6526811 -3.2.1.4 * euphausia pacifica 48000.0 2 PMID:22981467 -3.2.1.4 * fibrobacter succinogenes 58000.0 2 PMID:11167135;PMID:9172367 -3.2.1.4 * fomitopsis palustris 47000.0 2 PMID:18051302 -3.2.1.4 * fusarium verticillioides 25000.0 1 PMID:4215808 -3.2.1.4 * ganoderma lucidum 64000.0 1 PMID:25895101 -3.2.1.4 * gecarcoidea natalis 52000.0 1 PMID:18587122 -3.2.1.4 * geobacillus sp. kp43 66000.0 1 PMID:35601142 -3.2.1.4 * gymnascella citrina 43000.0 2 PMID:18228067 -3.2.1.4 * haloarcula sp. 36000.0 1 PMID:23999019 -3.2.1.4 * irpex lacteus 56000.0 2 PMID:7400113;PMID:8437 -3.2.1.4 * lathyrus oleraceus 71000.0 4 * -3.2.1.4 * lenzites trabea 29000.0 1 * -3.2.1.4 * lyrodus pedicellatus 40000.0 1 PMID:15973054;PMID:24657377;PMID:25387612 -3.2.1.4 * lysinibacillus sphaericus 183000.0 2 PMID:14758556 -3.2.1.4 * lysobacter sp. 41241.0 2 PMID:17031054 -3.2.1.4 * mahella australiensis 44000.0 1 PMID:32387598 -3.2.1.4 * marinobacter sp. 68000.0 1 PMID:19711200 -3.2.1.4 * melanocarpus albomyces 53780.0 8 PMID:18635283 -3.2.1.4 * mesocentrotus nudus 54000.0 1 PMID:17320379;PMID:20381456 -3.2.1.4 * mucor circinelloides 27000.0 2 * -3.2.1.4 * mycothermus thermophilus 57000.0 2 PMID:23564627 -3.2.1.4 * neobacillus sedimentimangrovi 45000.0 1 PMID:36152593 -3.2.1.4 * neocallimastix frontalis 113000.0 7 PMID:8579830 -3.2.1.4 * neurospora crassa 46500.0 5 PMID:1368541;PMID:25711741 -3.2.1.4 * niallia circulans 82000.0 2 PMID:7793925 -3.2.1.4 * novosphingobium sp. 25000.0 1 PMID:18704277;PMID:35124880 -3.2.1.4 * orpinomyces joyonii 58000.0 2 PMID:11167135 -3.2.1.4 * paenibacillus barcinonensis 58600.0 1 PMID:23124341 -3.2.1.4 * parageobacillus thermoglucosidasius 33000.0 1 PMID:36074980 -3.2.1.4 * penicillium chrysogenum 34500.0 1 PMID:5661595 -3.2.1.4 * phaseolus vulgaris 70000.0 1 PMID:7710279 -3.2.1.4 * phialophora sp. cgmcc 3328 56000.0 4 PMID:22868008 -3.2.1.4 * phytophthora infestans 21000.0 1 * -3.2.1.4 * pomacea maculata 45000.0 3 PMID:12963347;PMID:16215638 -3.2.1.4 * populus alba 50000.0 1 PMID:18417637 -3.2.1.4 * populus x canadensis 48000.0 2 PMID:7640890 -3.2.1.4 * psacothea hilaris 47000.0 1 PMID:12899703 -3.2.1.4 * pseudoalteromonas sp. 52700.0 1 PMID:16133657 -3.2.1.4 * pseudomonas putida 85000.0 1 PMID:18239944 -3.2.1.4 * psychrobacter aquimaris 56290.0 2 PMID:30712248 -3.2.1.4 * pyrococcus furiosus 35988.0 3 PMID:22577872;PMID:25387612;PMID:9864341 -3.2.1.4 * pyrococcus horikoshii 45561.0 6 PMID:11772658;PMID:15973054;PMID:19052378;PMID:22344652;PMID:24657377;PMID:25387612 -3.2.1.4 * rasamsonia emersonii 37000.0 3 PMID:24668246;PMID:3977838 -3.2.1.4 * reticulitermes speratus 42000.0 2 PMID:9134711 -3.2.1.4 * rhizobium leguminosarum bv. trifolii 33200.0 1 PMID:18458328 -3.2.1.4 * rhizopus arrhizus 61000.0 2 * -3.2.1.4 * robillarda sp. 59000.0 3 * -3.2.1.4 * ruminiclostridium cellulolyticum 94000.0 3 PMID:10714996;PMID:11844767 -3.2.1.4 * ruminiclostridium josui 45000.0 2 PMID:17685540;PMID:2500422 -3.2.1.4 * ruminococcus albus 67103.0 4 PMID:10705451 -3.2.1.4 * saccharolobus solfataricus 57000.0 8 PMID:15456402;PMID:18568289;PMID:22821975;PMID:23627611 -3.2.1.4 * salinivibrio sp. ntu-05 29000.0 1 * -3.2.1.4 * salipaludibacillus agaradhaerens 38000.0 1 PMID:16710633 -3.2.1.4 * sclerotinia sclerotiorum 34000.0 5 PMID:24146430 -3.2.1.4 * sporocytophaga myxococcoides 52000.0 2 * -3.2.1.4 * staphylotrichum coccosporum 49000.0 2 PMID:18408068 -3.2.1.4 * streptomyces reticuli 48000.0 2 PMID:16348033 -3.2.1.4 * streptomyces rochei 29000.0 1 PMID:8659894 -3.2.1.4 * streptomyces ruber 27000.0 2 * -3.2.1.4 * streptomyces sp. 26000.0 1 * -3.2.1.4 * syncephalastrum racemosum 55000.0 1 PMID:18083533;PMID:25331339 -3.2.1.4 * talaromyces funiculosus 56000.0 1 PMID:8437 -3.2.1.4 * teleogryllus emma 75500.0 2 PMID:18514003;PMID:29355625 -3.2.1.4 * teredinibacter waterburyi 45000.0 2 PMID:37016457 -3.2.1.4 * thermoascus aurantiacus 78000.0 9 PMID:15322773;PMID:28626700;PMID:6781492 -3.2.1.4 * thermobifida fusca 94000.0 1 * -3.2.1.4 * thermochaetoides thermophila 69800.0 6 PMID:10974122;PMID:23564627;PMID:29842954 -3.2.1.4 * thermomyces lanuginosus 71000.0 1 * -3.2.1.4 * thermosipho sp. ld-2008 40000.0 1 * -3.2.1.4 * thermothelomyces thermophilus 100000.0 2 PMID:28591592 -3.2.1.4 * thermotoga maritima 38000.0 2 PMID:16710633;PMID:23627611 -3.2.1.4 * thermotoga petrophila 38000.0 1 PMID:26122986 -3.2.1.4 * trichoderma harzianum 50000.0 2 PMID:20823521 -3.2.1.4 * trichoderma koningii 78100.0 5 PMID:417727 -3.2.1.4 * trichoderma longibrachiatum 45000.0 1 PMID:17685540;PMID:2500422 -3.2.1.4 * trichoderma reesei 72000.0 7 PMID:15950056;PMID:1624124;PMID:19251882 -3.2.1.4 * trichoderma sp. 51000.0 1 PMID:15322773;PMID:6781492 -3.2.1.4 * trichoderma viride 585000.0 12 PMID:12153;PMID:237002;PMID:3917923 -3.2.1.4 * uncultured bacterium 62600.0 5 PMID:25545469;PMID:26191525 -3.2.1.4 * uncultured rumen bacterium 40000.0 2 * -3.2.1.4 * unidentified microorganism 42100.0 2 PMID:11722552;PMID:16584799 -3.2.1.4 * volvariella volvacea 42000.0 1 PMID:11722552;PMID:16584799 -3.2.1.4 * xanthomonas sp. ec102 52000.0 1 PMID:24399319 -3.2.1.4 * xylella fastidiosa 60000.0 1 PMID:16874548 -3.2.1.40 * acrostalagmus luteoalbus 109000.0 1 PMID:21221705 -3.2.1.40 * alternaria alternata 135000.0 2 PMID:30100482 -3.2.1.40 * aspergillus aculeatus 92000.0 3 PMID:11319105;PMID:7972516 -3.2.1.40 * aspergillus luchuensis 90000.0 2 PMID:18633609 -3.2.1.40 * aspergillus nidulans 102000.0 1 PMID:10972728 -3.2.1.40 * aspergillus niger 85000.0 1 PMID:9435109 -3.2.1.40 * aspergillus oryzae 75000.0 1 * -3.2.1.40 * aspergillus terreus 98000.0 2 PMID:30387766 -3.2.1.40 * aspergillus tubingensis 110000.0 1 PMID:30789260 -3.2.1.40 * bacillus sp. (in: firmicutes) 500000.0 7 PMID:10415111;PMID:12831847 -3.2.1.40 * bacteroides jy-6 240000.0 2 PMID:8996636 -3.2.1.40 * bacteroides thetaiotaomicron 86000.0 2 PMID:29430381;PMID:30243237 -3.2.1.40 * dictyoglomus thermophilum 106000.0 1 * -3.2.1.40 * fagopyrum esculentum 70000.0 1 PMID:1261553 -3.2.1.40 * fusarium verticillioides 36000.0 1 PMID:30476650 -3.2.1.40 * fusobacterium sp. 170000.0 2 * -3.2.1.40 * novosphingobium sp. pp1y 101000.0 2 PMID:29678627 -3.2.1.40 * ogataea angusta 90000.0 2 PMID:11129592 -3.2.1.40 * penicillium tardum 95000.0 1 PMID:35670906 -3.2.1.40 * sphingomonas paucimobilis 112000.0 1 PMID:10648106 -3.2.1.40 * thermoclostridium stercorarium 95000.0 1 PMID:10632887 -3.2.1.40 * thermomicrobia bacterium 210000.0 4 * -3.2.1.40 * thermotoga maritima 233200.0 2 PMID:31685873 -3.2.1.41 * anaerobranca gottschalkii 96000.0 1 PMID:15184138 -3.2.1.41 * anoxybacillus sp. 80000.0 1 PMID:11676027;PMID:27000839 -3.2.1.41 * aureobasidium pullulans 73000.0 1 * -3.2.1.41 * avena sativa 85000.0 1 * -3.2.1.41 * bacillus acidopullulyticus 116000.0 3 PMID:10357001 -3.2.1.41 * bacillus cereus 110000.0 1 * -3.2.1.41 * bacillus sp. (in: firmicutes) 120000.0 3 PMID:1552852;PMID:238632;PMID:7764261 -3.2.1.41 * bacillus subtilis 81100.0 2 PMID:16582490 -3.2.1.41 * bacteroides thetaiotaomicron 77000.0 1 PMID:2703467 -3.2.1.41 * beta vulgaris 67000.0 1 PMID:16665444 -3.2.1.41 * desulfurococcus mucosus 74000.0 1 PMID:11053376 -3.2.1.41 * exiguobacterium acetylicum 100000.0 2 PMID:25273816 -3.2.1.41 * exiguobacterium sp. 110000.0 1 PMID:26349928 -3.2.1.41 * fervidobacterium pennivorans 776000.0 2 PMID:16535541 -3.2.1.41 * geobacillus stearothermophilus 83000.0 2 PMID:1444355;PMID:16347785 -3.2.1.41 * geobacillus thermocatenulatus 80370.0 2 PMID:30222339 -3.2.1.41 * geobacillus thermoleovorans 160000.0 2 PMID:18183386 -3.2.1.41 * halorubrum sp. ha25 14000.0 1 PMID:24122359 -3.2.1.41 * klebsiella aerogenes 143000.0 5 PMID:1552852;PMID:5043329;PMID:7764261;PMID:942714 -3.2.1.41 * klebsiella pneumoniae 120000.0 3 PMID:1552852;PMID:2181242;PMID:7764261 -3.2.1.41 * laceyella sacchari 79000.0 1 * -3.2.1.41 * lactococcus lactis 73900.0 1 PMID:21660865 -3.2.1.41 * metabacillus indicus 79100.0 1 PMID:37119334 -3.2.1.41 * micrococcus sp. 120000.0 1 PMID:1552852;PMID:7764261 -3.2.1.41 * niallia circulans 220000.0 2 PMID:7532585 -3.2.1.41 * oryza sativa 105000.0 3 PMID:18787715 -3.2.1.41 * paenibacillus barengoltzii 78000.0 3 PMID:26763762 -3.2.1.41 * priestia megaterium 112000.0 2 PMID:27858318 -3.2.1.41 * pyrococcus furiosus 135000.0 5 PMID:16349019;PMID:9293009 -3.2.1.41 * pyrococcus woesei 90000.0 1 PMID:7574598 -3.2.1.41 * sulfolobus acidocaldarius 435000.0 2 PMID:26104674 -3.2.1.41 * thermoanaerobacter ethanolicus 109000.0 1 PMID:11900114 -3.2.1.41 * thermoanaerobacter thermohydrosulfuricus 133000.0 2 PMID:1552852;PMID:3415657;PMID:7764261 -3.2.1.41 * thermoanaerobium sp. 120000.0 1 * -3.2.1.41 * thermococcus litoralis 125000.0 2 PMID:16349019 -3.2.1.41 * thermococcus siculi 148600.0 1 PMID:20593184 -3.2.1.41 * thermofilum pendens 65500.0 1 PMID:29551507 -3.2.1.41 * thermotoga neapolitana 93000.0 1 PMID:22112909 -3.2.1.41 * thermus aquaticus 83000.0 1 * -3.2.1.41 * thermus caldophilus 65000.0 1 PMID:9026441 -3.2.1.41 * thermus thermophilus 80000.0 2 PMID:11676027;PMID:24316447;PMID:27000839 -3.2.1.41 * unidentified 112000.0 1 PMID:27858318 -3.2.1.41 * zea mays 105000.0 1 PMID:9880368 -3.2.1.45 * bos taurus 138000.0 6 PMID:1760158;PMID:17976508;PMID:4004822;PMID:6743300 -3.2.1.45 * homo sapiens 125000.0 19 PMID:10993715;PMID:1760158;PMID:17976508;PMID:2429587;PMID:25187293;PMID:3728974;PMID:4004822;PMID:4768898;PMID:6743300;PMID:7172089;PMID:880249 -3.2.1.45 * mus musculus 57000.0 1 PMID:3936851 -3.2.1.45 * paenibacillus sp. 92020.0 2 PMID:12153721;PMID:14561218 -3.2.1.45 * sus scrofa 63000.0 2 PMID:4004822;PMID:6743300 -3.2.1.46 * homo sapiens 760000.0 14 PMID:19147730;PMID:7458907;PMID:7852280;PMID:8399327;PMID:9760019 -3.2.1.46 * mus musculus 80000.0 1 PMID:17986221 -3.2.1.48 * actinomyces naeslundii 99320.0 1 PMID:7828936 -3.2.1.48 * anser anser 380000.0 2 PMID:2302412;PMID:807575 -3.2.1.48 * gallus gallus 270000.0 1 PMID:6641170 -3.2.1.48 * homo sapiens 280000.0 5 PMID:1692546;PMID:1717481;PMID:2302412;PMID:807575;PMID:8924896 -3.2.1.48 * mus musculus 220000.0 2 PMID:1182172;PMID:19358694 -3.2.1.48 * necturus maculosus 200000.0 1 PMID:11208720 -3.2.1.48 * oryctolagus cuniculus 220000.0 2 PMID:1182172 -3.2.1.48 * platyrrhini 260000.0 2 PMID:2113033 -3.2.1.48 * rattus rattus 290000.0 3 PMID:291933;PMID:4032078;PMID:6794628 -3.2.1.48 * sus scrofa 260000.0 3 PMID:7002920 -3.2.1.48 * xanthomonas axonopodis 64000.0 1 PMID:14702310 -3.2.1.49 * acremonium sp. 57000.0 2 * -3.2.1.49 * arenibacter latericius 84000.0 1 PMID:12126478 -3.2.1.49 * aspergillus niger 440000.0 11 PMID:18443780;PMID:21982820 -3.2.1.49 * asterina amurensis 430000.0 4 PMID:20139603 -3.2.1.49 * clostridium perfringens 724200.0 4 PMID:11185964;PMID:12204375;PMID:14965778 -3.2.1.49 * elizabethkingia meningoseptica 83000.0 4 PMID:30828159 -3.2.1.49 * gallus gallus 49100.0 2 PMID:1445396;PMID:8954893 -3.2.1.49 * homo sapiens 55600.0 4 PMID:14767536;PMID:20139603;PMID:29748462;PMID:30388774;PMID:6859854 -3.2.1.49 * katsuwonus pelamis 80000.0 3 PMID:3611044 -3.2.1.49 * patella vulgata 50000.0 1 PMID:18458 -3.2.1.49 * solenocera melantho 55000.0 1 * -3.2.1.49 * spirosoma linguale 9600.0 1 PMID:31186954 -3.2.1.49 * sus scrofa 102000.0 2 PMID:7391035 -3.2.1.50 * bitis arietans 102000.0 2 PMID:11673851 -3.2.1.50 * bos taurus 127500.0 2 PMID:4215452 -3.2.1.50 * homo sapiens 307000.0 11 PMID:102578;PMID:10833408;PMID:11237686;PMID:1783617 -3.2.1.50 * patella vulgata 217000.0 1 PMID:11946941 -3.2.1.51 * arabidopsis thaliana 38000.0 1 PMID:11788770 -3.2.1.51 * bacillus cereus 125350.0 2 PMID:33991676 -3.2.1.51 * bacillus fulminans 80000.0 1 PMID:4781053 -3.2.1.51 * bacteroides fragilis 85000.0 2 PMID:6250477 -3.2.1.51 * biomphalaria glabrata 141000.0 1 PMID:25218034 -3.2.1.51 * bombyx mori 89000.0 1 PMID:32561391 -3.2.1.51 * bos taurus 330000.0 2 PMID:3942781 -3.2.1.51 * brassica oleracea 200000.0 2 PMID:11788770;PMID:12042250;PMID:1260037;PMID:7458 -3.2.1.51 * canis lupus lupus 156000.0 2 PMID:10655154 -3.2.1.51 * chamelea gallina 200000.0 1 PMID:11788770;PMID:12042250;PMID:1260037;PMID:7458 -3.2.1.51 * cricetulus griseus 51000.0 1 PMID:7881175 -3.2.1.51 * dictyostelium discoideum 62000.0 1 PMID:1310316 -3.2.1.51 * drosophila ananassae 256000.0 3 PMID:16736526 -3.2.1.51 * drosophila melanogaster 80000.0 2 PMID:21708168 -3.2.1.51 * emticicia oligotrophica 100000.0 4 PMID:26941394 -3.2.1.51 * enterococcus gallinarum 58000.0 1 PMID:37511315 -3.2.1.51 * flavobacterium algicola 54300.0 2 PMID:34479010 -3.2.1.51 * fusarium oxysporum 80000.0 2 * -3.2.1.51 * fusarium proliferatum 67000.0 1 PMID:27984201 -3.2.1.51 * homo sapiens 390000.0 15 PMID:11788770;PMID:11870229;PMID:12042250;PMID:1260037;PMID:12604617;PMID:16773698;PMID:240814;PMID:39624;PMID:4052017;PMID:7054178;PMID:7407198;PMID:7458;PMID:9063971 -3.2.1.51 * lamellidens corrianus 56175.0 2 PMID:28610928 -3.2.1.51 * littorina littorea 220000.0 1 * -3.2.1.51 * macaca radiata 285000.0 2 PMID:1694531;PMID:96860 -3.2.1.51 * niallia circulans 285000.0 2 PMID:1694531;PMID:96860 -3.2.1.51 * octopus vulgaris 75000.0 1 PMID:7076646 -3.2.1.51 * paenibacillus thiaminolyticus 76800.0 2 PMID:26013545;PMID:35113503 -3.2.1.51 * patiria pectinifera 102000.0 2 PMID:30776756 -3.2.1.51 * pecten maximus 200000.0 2 PMID:11788770;PMID:12042250;PMID:1260037;PMID:7458 -3.2.1.51 * pedobacter sp. cau209 56000.0 3 PMID:12715078;PMID:32388762;PMID:37115252 -3.2.1.51 * penaeus monodon 233000.0 2 PMID:1764918 -3.2.1.51 * penicillium multicolor 180000.0 1 PMID:9720243 -3.2.1.51 * polititapes rhomboides 200000.0 1 PMID:11788770;PMID:12042250;PMID:1260037;PMID:7458 -3.2.1.51 * pomacea canaliculata 260000.0 4 PMID:240814;PMID:8470892;PMID:9063971 -3.2.1.51 * rattus sp. 220000.0 5 PMID:13077;PMID:26840;PMID:5017763;PMID:7317440 -3.2.1.51 * saccharolobus solfataricus 508000.0 8 PMID:12569098;PMID:15207718;PMID:16920738;PMID:17687508 -3.2.1.51 * streptomyces sp. 59000.0 3 PMID:11567900 -3.2.1.51 * sus scrofa 192000.0 2 PMID:13077;PMID:26840;PMID:7317440 -3.2.1.51 * thermotoga maritima 300000.0 1 PMID:14715651 -3.2.1.51 * thermus sp. 240000.0 2 PMID:12441672 -3.2.1.51 * trypanosoma cruzi 50000.0 1 PMID:12715078;PMID:32388762 -3.2.1.51 * unio elongatulus 67850.0 4 PMID:9168959 -3.2.1.51 * wenyingzhuangia fucanilytica 67721.0 3 PMID:27576198 -3.2.1.52 * aeromonas hydrophila 69000.0 1 PMID:18256480 -3.2.1.52 * aeromonas sp. 36000.0 1 PMID:14673545 -3.2.1.52 * arabidopsis thaliana 68000.0 6 PMID:17644627 -3.2.1.52 * aspergillus niger 149000.0 1 PMID:7440573 -3.2.1.52 * aspergillus oryzae 63000.0 2 PMID:21505251 -3.2.1.52 * aspergillus sp. 73000.0 1 PMID:17630125 -3.2.1.52 * aspergillus versicolor 170000.0 1 PMID:30603849 -3.2.1.52 * bacillus sp. (in: firmicutes) 75000.0 2 PMID:4196675;PMID:8085829 -3.2.1.52 * bipolaris sorokiniana 120000.0 2 PMID:12030703;PMID:6852008;PMID:9812383 -3.2.1.52 * bombyx mori 135000.0 12 PMID:20384789;PMID:26672;PMID:661599;PMID:990284 -3.2.1.52 * bos taurus 234000.0 12 PMID:11148210;PMID:18192;PMID:4041463;PMID:5065953;PMID:661599;PMID:990284 -3.2.1.52 * brassica oleracea 150000.0 4 PMID:1212212;PMID:1368749;PMID:9678259 -3.2.1.52 * canavalia ensiformis 100000.0 1 PMID:33155;PMID:5506280 -3.2.1.52 * capsicum annuum 300000.0 4 PMID:12359515;PMID:21030387 -3.2.1.52 * carica papaya 64100.0 1 * -3.2.1.52 * cellulomonas fimi 60970.0 2 PMID:16762038 -3.2.1.52 * citrullus lanatus 150000.0 1 PMID:1212212;PMID:1368749;PMID:9678259 -3.2.1.52 * coccidioides posadasii 68500.0 1 PMID:20109094 -3.2.1.52 * conidiobolus lamprauges 70000.0 1 * -3.2.1.52 * cupiennius salei 108000.0 1 PMID:7370275 -3.2.1.52 * escherichia coli 38000.0 3 PMID:1377 -3.2.1.52 * gallus gallus 69000.0 3 * -3.2.1.52 * geobacillus stearothermophilus 75000.0 2 PMID:4196675;PMID:6223923;PMID:8085829 -3.2.1.52 * glycine max 133000.0 1 * -3.2.1.52 * halocynthia roretzi 330000.0 3 PMID:6223923;PMID:8085829 -3.2.1.52 * helicella ericetorum 147000.0 2 PMID:33660 -3.2.1.52 * homo sapiens 260000.0 25 PMID:1404373;PMID:19040401;PMID:2139028;PMID:2423070;PMID:2976757;PMID:4811067;PMID:5038693;PMID:6219664;PMID:758959 -3.2.1.52 * hordeum vulgare 92000.0 1 * -3.2.1.52 * lathyrus oleraceus 210000.0 3 PMID:16665814 -3.2.1.52 * lupinus luteus 69000.0 3 PMID:1368749;PMID:2141285 -3.2.1.52 * mizuhopecten yessoensis 56000.0 1 PMID:7763885 -3.2.1.52 * mucor fragilis 125000.0 2 PMID:16347047 -3.2.1.52 * mugil cephalus 170000.0 1 PMID:2961751 -3.2.1.52 * mus musculus 62000.0 1 PMID:19040401 -3.2.1.52 * octopus vulgaris 120000.0 3 PMID:12030703;PMID:6852008;PMID:9812383 -3.2.1.52 * oryza sativa 52000.0 2 PMID:12297015 -3.2.1.52 * ostrinia furnacalis 128000.0 3 PMID:18959754 -3.2.1.52 * palythoa caribaeorum 25000.0 1 PMID:18171621 -3.2.1.52 * patella vulgata 136000.0 1 PMID:4418328 -3.2.1.52 * penaeus japonicus 110000.0 2 PMID:9063965 -3.2.1.52 * penicillium oxalicum 160000.0 6 PMID:12030703;PMID:2143152;PMID:21564548 -3.2.1.52 * phycomyces blakesleeanus 72000.0 1 * -3.2.1.52 * rattus norvegicus 525000.0 10 PMID:1482400;PMID:6222051 -3.2.1.52 * rhinella arenarum 50000.0 2 PMID:10984420 -3.2.1.52 * rhipicephalus microplus 127000.0 2 PMID:10425723 -3.2.1.52 * saccharolobus solfataricus 313000.0 3 PMID:24060745 -3.2.1.52 * sclerotinia fructigena 141000.0 1 PMID:4722441 -3.2.1.52 * serratia marcescens 95000.0 1 PMID:12617608 -3.2.1.52 * solanum lycopersicum 64000.0 1 * -3.2.1.52 * sotalia fluviatilis 10077.0 1 PMID:20349205 -3.2.1.52 * spodoptera frugiperda 110000.0 3 PMID:16684772 -3.2.1.52 * stachybotrys elegans 120000.0 2 PMID:12030703;PMID:6852008;PMID:9812383 -3.2.1.52 * streptomyces sp. 55000.0 4 PMID:6808308;PMID:9677388 -3.2.1.52 * styela plicata 132000.0 2 PMID:7118868 -3.2.1.52 * sus scrofa 160000.0 1 PMID:2143152;PMID:21564548 -3.2.1.52 * thermotoga maritima msb8 54000.0 1 PMID:19914575 -3.2.1.52 * thermotoga neapolitana 54000.0 1 PMID:19914575 -3.2.1.52 * trametes cinnabarina 120000.0 2 PMID:12030703;PMID:6852008;PMID:9812383 -3.2.1.52 * tremella fuciformis 125000.0 1 PMID:26672;PMID:990284 -3.2.1.52 * tribolium castaneum 72600.0 4 PMID:18342252 -3.2.1.52 * trichinella spiralis 50000.0 1 PMID:16242793 -3.2.1.52 * trichoderma harzianum 150000.0 7 PMID:1212212;PMID:1368749;PMID:14673545;PMID:14685768;PMID:2141285;PMID:9678259 -3.2.1.52 * trichomonas vaginalis 204000.0 1 PMID:11312579 -3.2.1.52 * trigonella foenum-graecum 180000.0 9 PMID:25183 -3.2.1.52 * tritrichomonas suis 150000.0 1 PMID:1212212;PMID:1368749;PMID:9678259 -3.2.1.52 * turbatrix aceti 124000.0 2 PMID:6465897 -3.2.1.52 * verruciconidia persicina 100000.0 2 PMID:33155;PMID:5506280 -3.2.1.52 * zea mays 70000.0 2 PMID:14593799 -3.2.1.53 * bacillus sp. (in: firmicutes) 54000.0 2 PMID:9378710 -3.2.1.53 * paenibacillus sp. 115000.0 1 PMID:21297160 -3.2.1.53 * rattus norvegicus 210000.0 2 PMID:6222051 -3.2.1.54 * alicyclobacillus acidocaldarius 66000.0 1 PMID:10650202;PMID:1644767 -3.2.1.54 * anoxybacillus flavithermus 148000.0 2 PMID:16310726 -3.2.1.54 * anoxybacillus flavithermus subsp. flavithermus 72000.0 2 * -3.2.1.54 * archaeoglobus fulgidus 73000.0 1 PMID:17921308 -3.2.1.54 * bacillus cereus 69900.0 2 PMID:36757622 -3.2.1.54 * bacillus sp. (in: firmicutes) 67000.0 4 PMID:10620329;PMID:10825529;PMID:16536613;PMID:9606956 -3.2.1.54 * escherichia coli 69000.0 2 PMID:10825529;PMID:17494995;PMID:17983358 -3.2.1.54 * evansella clarkii 979000.0 2 PMID:18824139 -3.2.1.54 * flavobacterium sp. 62000.0 1 PMID:10825529 -3.2.1.54 * flavobacterium sp. 92 209000.0 1 PMID:19014948 -3.2.1.54 * geobacillus stearothermophilus 67000.0 2 PMID:10825529 -3.2.1.54 * heyndrickxia coagulans 62000.0 2 PMID:10825529 -3.2.1.54 * klebsiella oxytoca 69000.0 2 PMID:10825529;PMID:8599539 -3.2.1.54 * laceyella sacchari 148000.0 2 PMID:16310726 -3.2.1.54 * lactobacillus sp. 62000.0 1 * -3.2.1.54 * lactococcus lactis 68700.0 1 * -3.2.1.54 * lysinibacillus sphaericus 95000.0 2 PMID:10825529 -3.2.1.54 * massilia timonae 260000.0 1 PMID:30149121 -3.2.1.54 * more 280000.0 1 PMID:17238236 -3.2.1.54 * niallia circulans 126000.0 2 * -3.2.1.54 * paenibacillus sp. 80000.0 1 PMID:15469727 -3.2.1.54 * pyrococcus furiosus 76084.0 2 PMID:15466542 -3.2.1.54 * thermoanaerobacter ethanolicus 66000.0 1 PMID:10825529 -3.2.1.54 * thermoanaerobacter thermohydrosulfuricus 68030.0 2 PMID:10650202;PMID:1644767 -3.2.1.54 * thermococcus kodakarensis 76400.0 1 PMID:25688178 -3.2.1.54 * thermococcus sp. 79000.0 3 PMID:11489857;PMID:23727807 -3.2.1.54 * thermotoga maritima 55000.0 1 PMID:10825529 -3.2.1.54 * thermotoga neapolitana 55000.0 1 PMID:17399996 -3.2.1.54 * unidentified 68000.0 1 PMID:16790023 -3.2.1.54 * xanthomonas campestris 55000.0 1 PMID:10825529 -3.2.1.55 * acetivibrio thermocellus 63000.0 5 PMID:24039988;PMID:24817722 -3.2.1.55 * alicyclobacillus sp. 57000.0 1 PMID:26628911 -3.2.1.55 * anoxybacillus kestanbolensis 58000.0 1 PMID:18679678 -3.2.1.55 * arabidopsis thaliana 80000.0 1 PMID:16798843 -3.2.1.55 * aspergillus awamori 65000.0 3 PMID:10656340;PMID:10949693;PMID:16348679 -3.2.1.55 * aspergillus luchuensis 80000.0 3 PMID:16385399;PMID:16784813 -3.2.1.55 * aspergillus nidulans 36000.0 1 PMID:8125239 -3.2.1.55 * aspergillus niger 128000.0 13 PMID:10656340;PMID:10923788;PMID:15299963;PMID:1814275;PMID:5452669;PMID:7763988;PMID:8125239 -3.2.1.55 * aspergillus oryzae 228000.0 4 PMID:16385399 -3.2.1.55 * aspergillus sojae 43000.0 4 * -3.2.1.55 * aspergillus terreus 90000.0 5 * -3.2.1.55 * aureobasidium pullulans 49900.0 3 PMID:17955189 -3.2.1.55 * bacillus pumilus 220000.0 2 PMID:12523971;PMID:16385399 -3.2.1.55 * bacillus sp. (in: firmicutes) 55000.0 1 PMID:26481625 -3.2.1.55 * bacillus subtilis 356000.0 11 PMID:10949693;PMID:16348679;PMID:17426966;PMID:18757805;PMID:23797805;PMID:7944374 -3.2.1.55 * bifidobacterium adolescentis 87000.0 3 PMID:20971079 -3.2.1.55 * bifidobacterium breve 60000.0 1 PMID:14660356 -3.2.1.55 * bifidobacterium longum 260000.0 3 PMID:10923788;PMID:12957891;PMID:16385399;PMID:7887599 -3.2.1.55 * brevibacillus brevis 60000.0 1 PMID:10656340;PMID:10923788;PMID:8125239 -3.2.1.55 * butyrivibrio fibrisolvens 240000.0 2 PMID:16348679 -3.2.1.55 * caldicellulosiruptor saccharolyticus 460000.0 6 PMID:20477891;PMID:23568202 -3.2.1.55 * cellvibrio japonicus 57000.0 3 PMID:11535122;PMID:16385399 -3.2.1.55 * chaetomium sp. 52900.0 2 * -3.2.1.55 * clostridium acetobutylicum 94000.0 2 * -3.2.1.55 * clostridium cellulovorans 138000.0 1 PMID:16385399 -3.2.1.55 * coprinopsis cinerea 48300.0 2 PMID:21307589 -3.2.1.55 * dichomitus squalens 60000.0 1 PMID:10656340;PMID:10923788;PMID:8125239 -3.2.1.55 * fusarium oxysporum 200000.0 3 PMID:10949693;PMID:14663498 -3.2.1.55 * fusarium oxysporum f. sp. dianthi 58000.0 1 * -3.2.1.55 * geobacillus stearothermophilus 333000.0 12 PMID:10923788;PMID:12777810;PMID:12957891;PMID:16385399;PMID:7887599 -3.2.1.55 * glycine max 87000.0 1 * -3.2.1.55 * hordeum vulgare 79200.0 8 PMID:11054116;PMID:11336650;PMID:12464603 -3.2.1.55 * kuraishia capsulata 250000.0 2 PMID:10923788 -3.2.1.55 * lacrimispora xylanisolvens 364000.0 2 * -3.2.1.55 * levilactobacillus brevis 181000.0 1 PMID:28485897 -3.2.1.55 * meripilus giganteus 69000.0 1 PMID:16944135 -3.2.1.55 * monilinia fructigena 40000.0 4 PMID:16348679;PMID:3663195 -3.2.1.55 * mycosarcoma maydis 67840.0 1 PMID:24394409 -3.2.1.55 * mycothermus thermophilus 94000.0 2 PMID:16944135 -3.2.1.55 * paenibacillus curdlanolyticus 56000.0 3 PMID:27663030 -3.2.1.55 * paenibacillus sp. 221500.0 3 PMID:24248090 -3.2.1.55 * paenibacillus woosongensis 52852.0 1 PMID:21193828 -3.2.1.55 * penicillium chrysogenum 85000.0 14 PMID:12726996;PMID:16385399;PMID:21181156;PMID:22410744 -3.2.1.55 * penicillium sp. 74000.0 3 PMID:12674349;PMID:21424337 -3.2.1.55 * pleurotus ostreatus 81500.0 1 PMID:22080345 -3.2.1.55 * podospora anserina 99350.0 1 PMID:24394409 -3.2.1.55 * pseudothermotoga thermarum 55000.0 1 PMID:26725313 -3.2.1.55 * pyrus pyrifolia 62000.0 1 PMID:15965025 -3.2.1.55 * ruminiclostridium josui 85000.0 2 PMID:30037546 -3.2.1.55 * ruminococcus albus 310000.0 3 PMID:16348679;PMID:6742828;PMID:7576552 -3.2.1.55 * saccharococcus caldoxylosilyticus 236000.0 2 PMID:17361432 -3.2.1.55 * saccharolobus solfataricus 82000.0 1 PMID:17033733 -3.2.1.55 * scopolia japonica 62000.0 1 * -3.2.1.55 * spinacia oleracea 118000.0 2 * -3.2.1.55 * streptomyces avermitilis 53000.0 1 PMID:18665359 -3.2.1.55 * streptomyces chartreusis 80000.0 4 PMID:10657233;PMID:16385399 -3.2.1.55 * streptomyces diastaticus 60000.0 2 PMID:1622210 -3.2.1.55 * streptomyces lividans 380000.0 3 * -3.2.1.55 * streptomyces purpurascens 495000.0 2 PMID:16348679 -3.2.1.55 * streptomyces sp. 92000.0 3 PMID:16348679;PMID:24420282 -3.2.1.55 * streptomyces sp. pc22 404000.0 1 PMID:18606539 -3.2.1.55 * streptomyces thermoviolaceus 37000.0 3 PMID:11999423;PMID:16385399 -3.2.1.55 * talaromyces funiculosus 33148.0 1 PMID:24731829 -3.2.1.55 * talaromyces purpureogenus 70000.0 8 PMID:10656340;PMID:16385399;PMID:18550352;PMID:20562284;PMID:26058539 -3.2.1.55 * thermoanaerobacter ethanolicus 85000.0 1 PMID:16385399 -3.2.1.55 * thermobacillus xylanilyticus 56102.0 5 PMID:10742272;PMID:11842234;PMID:16385399 -3.2.1.55 * thermobifida fusca 92000.0 3 PMID:12800498;PMID:16385399 -3.2.1.55 * thermoclostridium stercorarium 195000.0 2 PMID:7576552 -3.2.1.55 * thermomicrobia bacterium 350000.0 1 PMID:15604762 -3.2.1.55 * thermomicrobia bacterium pri-1686 350000.0 1 PMID:16385399 -3.2.1.55 * thermomyces dupontii 35000.0 1 PMID:21181156 -3.2.1.55 * thermotoga maritima 332000.0 2 PMID:15965714;PMID:16385399 -3.2.1.55 * thermotoga petrophila 57000.0 1 PMID:20872163 -3.2.1.55 * trichoderma koningii 50000.0 1 PMID:17002602 -3.2.1.55 * trichoderma reesei 53000.0 2 PMID:10473402 -3.2.1.55 * trichoderma sp. 89000.0 1 * -3.2.1.55 * uncultured rumen bacterium 42000.0 1 PMID:21720773 -3.2.1.55 * weissella sp. 142 88000.0 1 PMID:28485897 -3.2.1.55 * zea mays 76600.0 4 PMID:25608890 -3.2.1.56 * pedobacter heparinus 41800.0 1 PMID:8526872 -3.2.1.57 * aspergillus niger 91000.0 6 PMID:4650606;PMID:8987855;PMID:9169610 -3.2.1.57 * bacillus sp. (in: firmicutes) 200000.0 2 * -3.2.1.58 * abracris flavolineata 45000.0 1 PMID:11471729;PMID:17720633;PMID:26199012 -3.2.1.58 * achlya bisexualis 30000.0 1 * -3.2.1.58 * aplysia kurodai 33000.0 1 PMID:19883786 -3.2.1.58 * arcopilus cupreus 65000.0 1 PMID:27854040 -3.2.1.58 * aspergillus phoenicis 57000.0 1 * -3.2.1.58 * bipolaris zeicola 73000.0 1 PMID:9838227 -3.2.1.58 * candida albicans 107000.0 5 PMID:1583691;PMID:2515245;PMID:8436950 -3.2.1.58 * cellulomonas fimi 66000.0 2 PMID:25797391 -3.2.1.58 * chaetomium globosum 39500.0 1 PMID:37642922 -3.2.1.58 * coccidioides immitis 120000.0 1 PMID:1398946 -3.2.1.58 * coprinopsis cinerea 85000.0 2 PMID:11471729;PMID:17720633;PMID:26199012 -3.2.1.58 * cyberlindnera jadinii 61000.0 3 PMID:1033777;PMID:6751872 -3.2.1.58 * cyberlindnera saturnus 47500.0 4 PMID:19513709;PMID:20336338 -3.2.1.58 * fungi imperfecti 43000.0 1 PMID:20206 -3.2.1.58 * geotrichum lactis 61000.0 1 PMID:6751872 -3.2.1.58 * helix pomatia 82000.0 1 PMID:236727 -3.2.1.58 * hordeum vulgare 71000.0 3 PMID:8617814;PMID:9097482 -3.2.1.58 * kluyveromyces aestuarii 43000.0 1 PMID:20206 -3.2.1.58 * kluyveromyces phaseolosporus 61000.0 1 PMID:6751872 -3.2.1.58 * komagataella pastoris 47000.0 2 PMID:16427312 -3.2.1.58 * meyerozyma caribbica 47000.0 1 * -3.2.1.58 * neurospora crassa 82000.0 1 * -3.2.1.58 * penicillium sp. kh10 104000.0 1 PMID:19500674 -3.2.1.58 * periconia byssoides 35000.0 1 PMID:17242851 -3.2.1.58 * phanerodontia chrysosporium 78000.0 1 PMID:16614901 -3.2.1.58 * phytophthora infestans 83000.0 3 PMID:12620261 -3.2.1.58 * porodisculus pendulus 59500.0 2 * -3.2.1.58 * pyrenophora tritici-repentis 46700.0 1 PMID:24119405 -3.2.1.58 * pythium insidiosum 82200.0 3 PMID:20237199;PMID:26263509 -3.2.1.58 * rasamsonia emersonii 40000.0 1 PMID:20882275 -3.2.1.58 * rhizoctonia solani 62000.0 1 PMID:19022284 -3.2.1.58 * rhizomucor miehei 76500.0 2 PMID:25577102 -3.2.1.58 * saccharomyces cerevisiae 85000.0 8 PMID:11471729;PMID:17720633;PMID:2500920;PMID:26199012;PMID:6751872;PMID:6820801 -3.2.1.58 * strongylocentrotus purpuratus 68000.0 1 PMID:7054179 -3.2.1.58 * trichoderma asperellum 83100.0 2 PMID:12594027;PMID:18804353 -3.2.1.58 * trichoderma harzianum 78000.0 2 * -3.2.1.58 * trichoderma reesei 70000.0 1 PMID:7197155 -3.2.1.58 * trichoderma viride 61000.0 1 PMID:11733006 -3.2.1.58 * wickerhamomyces anomalus 49000.0 2 PMID:17895596;PMID:25044257 -3.2.1.58 * zea mays 60000.0 1 PMID:24301845 -3.2.1.59 * flavobacterium sp. 65000.0 1 PMID:370 -3.2.1.59 * niallia circulans 180000.0 3 * -3.2.1.59 * pseudomonas sp. 279000.0 1 PMID:7074138 -3.2.1.59 * schizosaccharomyces pombe 54000.0 5 PMID:15194814;PMID:17315266;PMID:37410615 -3.2.1.59 * streptomyces chartreusis 68000.0 1 PMID:7462159 -3.2.1.59 * streptomyces sp. 78000.0 1 * -3.2.1.59 * streptomyces thermodiastaticus 91000.0 3 PMID:28954965;PMID:32595199 -3.2.1.59 * trichoderma harzianum 274000.0 3 PMID:10636904 -3.2.1.59 * trichoderma viride 47000.0 1 PMID:5388595 -3.2.1.6 * alicyclobacillus sp. 60700.0 2 PMID:20169343 -3.2.1.6 * aplysia kurodai 36000.0 1 PMID:16374635;PMID:19883786 -3.2.1.6 * bacillus licheniformis 34000.0 4 PMID:16470364;PMID:17216453;PMID:24391357 -3.2.1.6 * bacillus subtilis 25500.0 2 PMID:18365147 -3.2.1.6 * chaetomium globosum 28800.0 1 PMID:37642922 -3.2.1.6 * cherax destructor 62000.0 3 PMID:18587122 -3.2.1.6 * cyberlindnera jadinii 21000.0 1 PMID:570837 -3.2.1.6 * flavobacterium dormitator 33000.0 2 * -3.2.1.6 * flavobacterium sp. 16600.0 1 PMID:4776863 -3.2.1.6 * haliotis discus hannai 33000.0 1 PMID:19446649 -3.2.1.6 * laceyella putida 36000.0 1 PMID:26392136 -3.2.1.6 * paenibacillus sp. 41561.0 2 PMID:25391729 -3.2.1.6 * paenibacillus sp. ccrc 17245 144600.0 5 PMID:18802694 -3.2.1.6 * periplaneta americana 25000.0 1 PMID:14563360 -3.2.1.6 * phanerodontia chrysosporium 36000.0 1 PMID:16374635;PMID:19883786 -3.2.1.6 * pseudocardium sachalinense 22000.0 1 PMID:5500926 -3.2.1.6 * rasamsonia emersonii 40700.0 3 PMID:11427240;PMID:24668246 -3.2.1.6 * rhizoctonia solani 29000.0 1 * -3.2.1.6 * rhizomucor miehei 39700.0 1 PMID:17589838 -3.2.1.6 * saccharomyces cerevisiae 160000.0 1 * -3.2.1.6 * streptococcus equinus jb1 24100.0 1 PMID:9327538 -3.2.1.6 * streptomyces sp. 99000.0 2 PMID:26888054 -3.2.1.6 * teredinibacter sp. 45000.0 2 PMID:37016457 -3.2.1.6 * theobroma cacao 25580.0 2 PMID:23666150 -3.2.1.6 * thermotoga neapolitana 73000.0 1 PMID:9168619 -3.2.1.6 * trichoderma harzianum 17000.0 1 * -3.2.1.60 * bacillus sp. (in: firmicutes) 97000.0 1 PMID:16535108 -3.2.1.60 * niallia circulans 10000.0 1 * -3.2.1.60 * roseateles saccharophilus 56000.0 2 PMID:1596923;PMID:22868150 -3.2.1.60 * stutzerimonas stutzeri 125000.0 8 PMID:11272837;PMID:1368535;PMID:5123132;PMID:9126844 -3.2.1.61 * niallia circulans 120000.0 1 * -3.2.1.61 * penicillium melinii 40000.0 1 PMID:4108250 -3.2.1.61 * streptomyces sp. 68000.0 2 PMID:11515560;PMID:1368944 -3.2.1.62 * homo sapiens 320000.0 13 PMID:1460044;PMID:17506819;PMID:17595169;PMID:3109375;PMID:3119597;PMID:6143571;PMID:6430296;PMID:6786877;PMID:6814489;PMID:7626235;PMID:8150089;PMID:9108312 -3.2.1.62 * mus musculus 300000.0 1 PMID:6790523 -3.2.1.62 * oryctolagus cuniculus 135000.0 1 PMID:1388157 -3.2.1.62 * rattus norvegicus 38000.0 1 PMID:18573506 -3.2.1.62 * rattus sp. 220000.0 2 PMID:3119597;PMID:9108312 -3.2.1.62 * sus scrofa 320000.0 4 PMID:1460044;PMID:3109375;PMID:6143571;PMID:6430296;PMID:6786877;PMID:6814489;PMID:8150089 -3.2.1.63 * bacillus cereus 196000.0 2 PMID:16233842 -3.2.1.63 * bacillus fulminans 80000.0 1 PMID:4781053 -3.2.1.63 * bifidobacterium bifidum 205000.0 1 PMID:15262925;PMID:16233817 -3.2.1.63 * clostridium perfringens 200000.0 1 PMID:4314593 -3.2.1.63 * xanthomonas phaseoli pv. manihotis 63000.0 1 PMID:31278898 -3.2.1.64 * microbacterium laevaniformans 68800.0 1 PMID:12095678 -3.2.1.64 * streptomyces exfoliatus 60000.0 2 PMID:10618232 -3.2.1.65 * actinomyces viscosus 89000.0 1 PMID:3679542 -3.2.1.65 * bacillus licheniformis 66000.0 2 PMID:25107977 -3.2.1.65 * bacillus sp. l7 86000.0 1 PMID:9297817 -3.2.1.65 * bacillus subtilis 75870.0 4 PMID:3112519;PMID:3120151;PMID:6618666 -3.2.1.65 * gluconacetobacter diazotrophicus 58400.0 3 PMID:12029520 -3.2.1.65 * pseudomonas sp. k-52 38000.0 1 PMID:9569612 -3.2.1.65 * pseudomonas sp. no. 43 36000.0 1 * -3.2.1.65 * rhodotorula sp. 39000.0 1 PMID:8672285 -3.2.1.65 * streptococcus salivarius 100000.0 1 PMID:6618666 -3.2.1.65 * streptomyces sp. 366l 80000.0 2 * -3.2.1.65 * treponema zioleckii 60000.0 1 PMID:20298795 -3.2.1.67 * acrophialophora nainiana 30750.0 1 PMID:16337707 -3.2.1.67 * aspergillus giganteus 69700.0 1 PMID:20204453 -3.2.1.67 * aspergillus niger 106000.0 10 PMID:12204327;PMID:18500582;PMID:23069766 -3.2.1.67 * aspergillus niveus 102600.0 1 PMID:23613286 -3.2.1.67 * aspergillus tubingensis 78000.0 1 PMID:8856078 -3.2.1.67 * aureobasidium pullulans 54000.0 1 PMID:15787251 -3.2.1.67 * bacillus subtilis 56000.0 1 * -3.2.1.67 * botrytis cinerea 65000.0 2 PMID:12398287 -3.2.1.67 * caldicellulosiruptor bescii 51000.0 2 PMID:24705464 -3.2.1.67 * daucus carota 55000.0 4 PMID:12244438;PMID:16402551 -3.2.1.67 * fusarium oxysporum 68000.0 2 * -3.2.1.67 * fusarium oxysporum f. sp. cubense 63000.0 4 PMID:21920035 -3.2.1.67 * geotrichum lactis 53000.0 1 * -3.2.1.67 * klebsiella sp. y1 72200.0 1 PMID:22940315 -3.2.1.67 * malus domestica 58000.0 1 * -3.2.1.67 * marchantia polymorpha 76000.0 1 PMID:16663197 -3.2.1.67 * moniliophthora perniciosa 43130.0 2 PMID:24140149 -3.2.1.67 * paecilomyces variotii 77300.0 2 PMID:19484410;PMID:23729888 -3.2.1.67 * penicillium expansum 41000.0 1 PMID:19968548 -3.2.1.67 * penicillium glabrum 79000.0 3 PMID:11911610 -3.2.1.67 * penicillium viridicatum 92000.0 2 PMID:20148174 -3.2.1.67 * prunus persica 68000.0 2 PMID:16658542 -3.2.1.67 * rhizomucor pusillus 43500.0 1 PMID:28025649 -3.2.1.67 * rhizopus arrhizus 75500.0 1 * -3.2.1.67 * solanum lycopersicum 47000.0 1 * -3.2.1.67 * streptomyces erumpens 63000.0 1 * -3.2.1.67 * thermoascus aurantiacus 29300.0 1 PMID:24159381 -3.2.1.67 * thermotoga maritima 212000.0 2 PMID:12791288;PMID:16262687 -3.2.1.67 * trametes sanguinea 42000.0 1 PMID:19781642 -3.2.1.67 * zea mays 51000.0 1 * -3.2.1.68 * amaranthus cruentus 90500.0 1 PMID:25167854 -3.2.1.68 * arabidopsis thaliana 750000.0 3 PMID:24098685 -3.2.1.68 * bacillus sp. (in: firmicutes) 101155.0 3 PMID:23494708 -3.2.1.68 * chlamydomonas reinhardtii 180000.0 2 PMID:24993830 -3.2.1.68 * cytophaga sp. 120000.0 1 * -3.2.1.68 * dickeya chrysanthemi 74100.0 2 PMID:11554733 -3.2.1.68 * flavobacterium sp. 83000.0 1 PMID:9197405 -3.2.1.68 * lipomyces kononenkoae 65000.0 1 PMID:16346143 -3.2.1.68 * myroides odoratus 83000.0 1 * -3.2.1.68 * oryza sativa 830000.0 9 PMID:10333591;PMID:16953433;PMID:21551159 -3.2.1.68 * phaseolus vulgaris 370000.0 8 PMID:17827690 -3.2.1.68 * pseudomonas sp. 'amyloderamosa' 95000.0 13 PMID:3379068;PMID:5456995;PMID:7357015;PMID:9719642 -3.2.1.68 * rhizopus arrhizus 68000.0 1 PMID:31868558 -3.2.1.68 * saccharolobus solfataricus 830000.0 1 PMID:17485831 -3.2.1.68 * solanum tuberosum 520000.0 4 * -3.2.1.68 * zea mays 400000.0 10 PMID:20448101;PMID:23952574;PMID:24027240;PMID:9625695 -3.2.1.7 * arthrobacter sp. 87900.0 3 PMID:19122997 -3.2.1.7 * aspergillus ficuum 66000.0 7 PMID:1368526;PMID:19122997 -3.2.1.7 * aspergillus fumigatus 200000.0 3 PMID:16171693;PMID:25369893 -3.2.1.7 * aspergillus neotritici 53700.0 1 PMID:32890562 -3.2.1.7 * aspergillus niger 69000.0 4 PMID:19122997;PMID:22813590 -3.2.1.7 * aspergillus sp. 53000.0 1 * -3.2.1.7 * kluyveromyces marxianus 77000.0 3 PMID:19122997 -3.2.1.7 * meyerozyma guilliermondii 60000.0 2 PMID:18821076 -3.2.1.7 * penicillium sp. 68000.0 1 PMID:19122997 -3.2.1.7 * pseudogymnoascus pannorum 56000.0 1 * -3.2.1.7 * streptomyces griseus 104000.0 1 * -3.2.1.7 * talaromyces purpureogenus 64000.0 2 PMID:19122997 -3.2.1.7 * xanthomonas oryzae 139000.0 1 * -3.2.1.70 * arthrobacter globiformis 120000.0 4 PMID:16233603 -3.2.1.70 * lipomyces lipofer 29000.0 1 PMID:6193756 -3.2.1.70 * streptococcus mutans 63000.0 2 PMID:16503208;PMID:18395742 -3.2.1.71 * acremonium sp. 36000.0 1 * -3.2.1.72 * vibrio sp. 60000.0 1 PMID:17993567 -3.2.1.73 * acetivibrio thermocellus 35000.0 2 PMID:2043130;PMID:25005095 -3.2.1.73 * aspergillus niger 27900.0 1 * -3.2.1.73 * bacillus altitudinis 45000.0 2 PMID:23292246 -3.2.1.73 * bacillus halotolerans 32000.0 1 PMID:31136163 -3.2.1.73 * bacillus licheniformis 55000.0 6 PMID:16470364;PMID:17216453;PMID:22653681 -3.2.1.73 * bacillus pumilus 75000.0 3 PMID:27838418 -3.2.1.73 * bacillus sp. (in: firmicutes) 26800.0 2 PMID:23355080;PMID:7222749 -3.2.1.73 * bacillus sp. sj-10 24000.0 1 PMID:31112758 -3.2.1.73 * bacillus subtilis 90000.0 9 PMID:18172721;PMID:18350387;PMID:21174947;PMID:24391357;PMID:2494179;PMID:34409950 -3.2.1.73 * bacillus tequilensis 26900.0 2 PMID:24728764 -3.2.1.73 * bacteroides ovatus 31000.0 1 PMID:16721874 -3.2.1.73 * bacteroides uniformis 31000.0 1 PMID:16721874 -3.2.1.73 * bispora sp. 48000.0 2 PMID:19590866 -3.2.1.73 * brevibacillus brevis 29000.0 1 PMID:7763386 -3.2.1.73 * chaetomium sp. cq31 26100.0 2 PMID:34329700 -3.2.1.73 * clostridium perfringens 55000.0 1 PMID:16721874 -3.2.1.73 * enterococcus faecium 63000.0 1 PMID:16721874 -3.2.1.73 * fibrobacter succinogenes 37200.0 3 PMID:17694302;PMID:3063255 -3.2.1.73 * hordeum vulgare 33800.0 7 PMID:11391016;PMID:6799294;PMID:8358032;PMID:8622963 -3.2.1.73 * laetiporus sulphureus 52000.0 2 PMID:19734720 -3.2.1.73 * macrotermes barneyi 35000.0 1 PMID:32725373 -3.2.1.73 * malbranchea cinnamomea 46900.0 2 PMID:25113013 -3.2.1.73 * orpinomyces sp. 27929.0 2 PMID:9324248 -3.2.1.73 * oryza sativa 32000.0 2 * -3.2.1.73 * paecilomyces sp. 38600.0 3 PMID:18543932 -3.2.1.73 * paecilomyces sp. 'thermophila' 38500.0 2 PMID:20645085 -3.2.1.73 * paenibacillus sp. 239000.0 4 PMID:24322768;PMID:25391729 -3.2.1.73 * penicillium occitanis (nom. inval.) 20000.0 1 * -3.2.1.73 * rhizomucor miehei 35400.0 3 PMID:22309761 -3.2.1.73 * rhizopus microsporus 36500.0 2 PMID:17147821 -3.2.1.73 * streptococcus equinus 60000.0 2 PMID:16721874;PMID:36449894 -3.2.1.73 * thermoascus aurantiacus 31000.0 1 PMID:30216845 -3.2.1.73 * thermomonospora sp. 66730.0 4 PMID:17689169 -3.2.1.73 * triticum aestivum 30000.0 1 PMID:8358032 -3.2.1.73 * uncultured bacterium 42000.0 1 PMID:33482202 -3.2.1.73 * uncultured microorganism 60600.0 3 PMID:21455595;PMID:25152058 -3.2.1.73 * vreelandella aquamarina 72000.0 1 PMID:36740637 -3.2.1.74 * caldicellulosiruptor bescii 23000.0 1 PMID:9493383 -3.2.1.74 * cellulomonas fimi 49300.0 2 PMID:3134347 -3.2.1.74 * chaetomium globosum 88000.0 1 PMID:12916726 -3.2.1.74 * clostridium cellulovorans 51570.0 1 PMID:16930544 -3.2.1.74 * fibrobacter succinogenes subsp. succinogenes s85 77000.0 2 PMID:18203823 -3.2.1.74 * gecarcoidea natalis 169300.0 2 PMID:20709923 -3.2.1.74 * irpex lacteus 56000.0 4 PMID:16232497;PMID:16233004 -3.2.1.74 * komagataeibacter xylinus 81200.0 1 * -3.2.1.74 * nakazawaea wickerhamii 151000.0 2 PMID:3093475 -3.2.1.74 * pseudomonas fluorescens 80000.0 1 * -3.2.1.74 * ruminiclostridium papyrosolvens 85000.0 1 PMID:9569613 -3.2.1.74 * ruminococcus albus 200000.0 4 PMID:2119579 -3.2.1.74 * ruminococcus flavefaciens 112000.0 1 * -3.2.1.74 * sporotrichum pulverulentum 48600.0 1 PMID:235428 -3.2.1.74 * stereum hirsutum 780000.0 2 PMID:20532763 -3.2.1.74 * talaromyces funiculosus 65000.0 2 * -3.2.1.74 * thermoclostridium stercorarium 87000.0 1 PMID:1909625;PMID:7592339 -3.2.1.74 * thermomonospora sp. 14200.0 1 PMID:15721281 -3.2.1.74 * thermotoga maritima 29000.0 1 PMID:7747960 -3.2.1.74 * uncultured bacterium 40000.0 2 * -3.2.1.74 * vibrio cholerae serotype o1 65000.0 2 PMID:12042307 -3.2.1.74 * xylanibacter ruminicola 87000.0 1 PMID:1909625;PMID:7592339 -3.2.1.75 * acinetobacter sp. 55000.0 2 * -3.2.1.75 * acremonium sp. 41200.0 1 PMID:14757248 -3.2.1.75 * aspergillus fumigatus 50000.0 1 PMID:19039584 -3.2.1.75 * chlamys albidus 20000.0 1 * -3.2.1.75 * fusarium fujikuroi 37000.0 1 * -3.2.1.75 * lentinula edodes 49000.0 1 PMID:21523473 -3.2.1.75 * neotyphodium sp. 47000.0 1 PMID:12427996 -3.2.1.75 * niallia circulans 54000.0 1 PMID:4309 -3.2.1.75 * penicillium brefeldianum 44000.0 1 PMID:6508737 -3.2.1.75 * penicillium multicolor 51000.0 2 PMID:23246473 -3.2.1.75 * rhizopus microsporus var. chinensis 30500.0 2 * -3.2.1.75 * saccharomycopsis fibuligera 51000.0 2 PMID:7891593 -3.2.1.75 * streptomyces rochei 60000.0 1 PMID:12507000 -3.2.1.75 * streptomyces sp. ef-14 65000.0 1 PMID:11693907 -3.2.1.75 * trichoderma harzianum 51000.0 6 PMID:10491168;PMID:15982190;PMID:33309029;PMID:9795258 -3.2.1.75 * verruciconidia persicina 44300.0 2 PMID:8670160 -3.2.1.76 * homo sapiens 480000.0 29 PMID:11555618;PMID:15170390;PMID:15300847;PMID:16439176;PMID:17203373;PMID:18758061;PMID:21778683;PMID:23026551;PMID:23143250;PMID:2470345;PMID:30407;PMID:3136;PMID:4993544;PMID:6421818;PMID:7098949 -3.2.1.76 * sus scrofa 70000.0 1 PMID:2917561 -3.2.1.78 * aeromonas hydrophila 24000.0 1 * -3.2.1.78 * agroathelia rolfsii 61200.0 2 * -3.2.1.78 * alicyclobacillus acidocaldarius 38000.0 1 PMID:18323611 -3.2.1.78 * aplysia kurodai 40000.0 2 PMID:20639136;PMID:21601647 -3.2.1.78 * aspergillus aculeatus 50000.0 3 PMID:11162394;PMID:7987261 -3.2.1.78 * aspergillus fischeri 43000.0 3 PMID:25466024 -3.2.1.78 * aspergillus fumigatus 63000.0 3 PMID:15541293;PMID:19205049 -3.2.1.78 * aspergillus nidulans 56000.0 4 PMID:21867780 -3.2.1.78 * aspergillus niger 66000.0 6 PMID:10525841;PMID:19884778;PMID:19912637;PMID:21632240;PMID:9803534 -3.2.1.78 * aspergillus sulphureus 48000.0 3 PMID:17194495 -3.2.1.78 * bacillus licheniformis 45000.0 2 PMID:20380743 -3.2.1.78 * bacillus sp. (in: firmicutes) 59000.0 3 * -3.2.1.78 * bacillus subtilis 41000.0 6 PMID:17294696;PMID:22450788 -3.2.1.78 * basidiomycota 53000.0 1 * -3.2.1.78 * bispora sp. 46800.0 1 PMID:18998121 -3.2.1.78 * caldicellulosiruptor saccharolyticus 146900.0 1 PMID:18378602 -3.2.1.78 * cellulomonas fimi 50000.0 1 PMID:16171384 -3.2.1.78 * cellulosimicrobium sp. 44000.0 2 PMID:21767948 -3.2.1.78 * clostridium cellulovorans 70000.0 1 PMID:21311881 -3.2.1.78 * coffea arabica 43000.0 1 PMID:11469596 -3.2.1.78 * dictyoglomus thermophilum 40000.0 1 PMID:10525841;PMID:9803534 -3.2.1.78 * dictyoglomus turgidum 43000.0 1 PMID:29177717 -3.2.1.78 * geobacillus stearothermophilus 162000.0 2 PMID:2176449 -3.2.1.78 * haliotis discus hannai 39627.0 2 PMID:16621092 -3.2.1.78 * helix pomatia 37000.0 1 * -3.2.1.78 * hordeum vulgare 43000.0 1 PMID:16771710 -3.2.1.78 * hypothenemus hampei 35500.0 2 PMID:23965285 -3.2.1.78 * lactuca sativa 46000.0 1 PMID:24407322 -3.2.1.78 * lilium testaceum 33000.0 1 * -3.2.1.78 * medicago sativa 41000.0 1 * -3.2.1.78 * mytilus edulis 39265.0 4 PMID:11689251;PMID:16487541 -3.2.1.78 * niallia circulans 32000.0 2 PMID:18239434;PMID:18820840 -3.2.1.78 * paenibacillus polymyxa 145294.0 1 PMID:16912849 -3.2.1.78 * paenibacillus sp. 53600.0 1 PMID:20372022 -3.2.1.78 * pediococcus acidilactici 38000.0 1 * -3.2.1.78 * penicillium freii 72000.0 2 PMID:22382013 -3.2.1.78 * penicillium occitanis (nom. inval.) 18000.0 1 PMID:19418261 -3.2.1.78 * phanerodontia chrysosporium 65000.0 1 * -3.2.1.78 * reinekea sp. kit-yo10 44300.0 1 PMID:25036974 -3.2.1.78 * rhizomucor miehei 43000.0 1 PMID:23252695 -3.2.1.78 * rhodothermus marinus 113000.0 1 PMID:10919332 -3.2.1.78 * scenedesmus fuscus 70000.0 4 PMID:24241623;PMID:24258585 -3.2.1.78 * sesbania virgata 36000.0 2 * -3.2.1.78 * solanum lycopersicum 42400.0 4 PMID:15840830;PMID:16649044;PMID:9421930 -3.2.1.78 * talaromyces purpureogenus 57000.0 1 * -3.2.1.78 * thermotoga neapolitana 65000.0 2 PMID:18629900;PMID:8979350 -3.2.1.78 * thermotoga petrophila 44000.0 1 PMID:20823531 -3.2.1.78 * vibrio sp. 76309.0 7 PMID:19129644;PMID:8534110 -3.2.1.78 * xanthomonas campestris 33000.0 1 PMID:20073482 -3.2.1.8 * acacia verek 60000.0 2 * -3.2.1.8 * acetivibrio thermocellus 61200.0 3 PMID:26387816;PMID:27146990;PMID:27841749 -3.2.1.8 * acrophialophora nainiana 54000.0 2 PMID:12829303 -3.2.1.8 * albifimbria verrucaria 15900.0 1 * -3.2.1.8 * alicyclobacillus sp. 42500.0 1 PMID:19916085 -3.2.1.8 * arthrobacter sp. 131500.0 2 * -3.2.1.8 * aspergillus caespitosus 27000.0 4 * -3.2.1.8 * aspergillus cf. niger bcc14405 24000.0 2 PMID:15715941 -3.2.1.8 * aspergillus fumigatus 66000.0 4 PMID:10830514;PMID:16091777;PMID:21369910;PMID:24888408;PMID:26847222;PMID:31799141 -3.2.1.8 * aspergillus giganteus 24000.0 2 PMID:15114860 -3.2.1.8 * aspergillus japonicus 25100.0 1 PMID:20159568 -3.2.1.8 * aspergillus luchuensis 23300.0 2 PMID:26686608 -3.2.1.8 * aspergillus nidulans 34000.0 1 PMID:24232655 -3.2.1.8 * aspergillus niger 50000.0 13 PMID:10830514;PMID:16091777;PMID:17988729;PMID:18553703;PMID:18553704;PMID:18553705;PMID:19078;PMID:20467831;PMID:21369910;PMID:23670313;PMID:24888408;PMID:455113 -3.2.1.8 * aspergillus ochraceus 50000.0 2 PMID:18592516 -3.2.1.8 * aspergillus terreus 33000.0 1 PMID:29684454 -3.2.1.8 * aspergillus versicolor 32000.0 1 PMID:8467959 -3.2.1.8 * bacillus amyloliquefaciens 18500.0 1 * -3.2.1.8 * bacillus cereus 23300.0 1 PMID:37843795 -3.2.1.8 * bacillus licheniformis 40000.0 4 PMID:16915648;PMID:18065237;PMID:18612683 -3.2.1.8 * bacillus pumilus 24000.0 3 PMID:10830514;PMID:16091777;PMID:21369910;PMID:24888408 -3.2.1.8 * bacillus sp. (in: firmicutes) 99000.0 16 PMID:10689076;PMID:10830514;PMID:15057452;PMID:16091777;PMID:19911836;PMID:20467831;PMID:21369910;PMID:22544563;PMID:22806794;PMID:23670313;PMID:24888408;PMID:9678255 -3.2.1.8 * bacillus subtilis 85500.0 9 PMID:16346375;PMID:18092465;PMID:18776691;PMID:19332293;PMID:20075612;PMID:22006920;PMID:27097633 -3.2.1.8 * bispora sp. mey-1 449000.0 4 PMID:19655217;PMID:20077114 -3.2.1.8 * botrytis cinerea 20600.0 1 PMID:16404950 -3.2.1.8 * caecomyces sp. cr4 82000.0 1 PMID:18791765 -3.2.1.8 * caldicellulosiruptor saccharolyticus 42000.0 2 PMID:8467959 -3.2.1.8 * carica papaya 64960.0 3 PMID:18251885 -3.2.1.8 * cellulomonas fimi 150000.0 3 * -3.2.1.8 * cellulomonas flavigena 49000.0 1 PMID:18379842 -3.2.1.8 * cellulosimicrobium cellulans 29000.0 1 PMID:24908422 -3.2.1.8 * cellulosimicrobium sp. 39000.0 1 PMID:18027102 -3.2.1.8 * cladosporium sp. 37000.0 2 PMID:30115321 -3.2.1.8 * clostridium acetobutylicum 65000.0 4 PMID:16347312 -3.2.1.8 * cryptococcus sp. (in: basidiomycete fungi) 22000.0 1 PMID:8987553 -3.2.1.8 * cutaneotrichosporon cutaneum 45000.0 1 * -3.2.1.8 * cytobacillus firmus 23000.0 1 PMID:19352037 -3.2.1.8 * demequina sp. jk4 49000.0 1 PMID:19884762 -3.2.1.8 * euphausia superba 45000.0 2 PMID:11126763 -3.2.1.8 * fusarium graminearum 23980.0 2 PMID:15629130 -3.2.1.8 * fusarium oxysporum 40000.0 2 PMID:23157299 -3.2.1.8 * fusarium oxysporum f. sp. vasinfectum 21200.0 1 PMID:27602054 -3.2.1.8 * fusarium proliferatum 25000.0 2 PMID:18668373 -3.2.1.8 * gelatoporia subvermispora 29000.0 1 PMID:16243455 -3.2.1.8 * geobacillus sp. wbi 47000.0 1 PMID:9145520 -3.2.1.8 * geobacillus stearothermophilus 43000.0 2 PMID:8328796 -3.2.1.8 * halalkalibacterium halodurans 47000.0 5 PMID:22544563;PMID:22806794;PMID:25553569;PMID:30138852 -3.2.1.8 * hordeum vulgare 61500.0 2 PMID:17383610;PMID:24232655 -3.2.1.8 * irpex lacteus 62000.0 2 PMID:4093442 -3.2.1.8 * laetiporus sulphureus 70000.0 2 PMID:19147106 -3.2.1.8 * lentinula edodes 90000.0 5 PMID:18092465 -3.2.1.8 * malbranchea cinnamomea 40500.0 1 PMID:25058752 -3.2.1.8 * malbranchea pulchella 30000.0 2 * -3.2.1.8 * massilia sp. rbm26 45000.0 1 PMID:26387816;PMID:27146990;PMID:27841749 -3.2.1.8 * melanocarpus albomyces 39800.0 16 PMID:10923787 -3.2.1.8 * melioribacter roseus 86000.0 3 PMID:25951846 -3.2.1.8 * meloidogyne incognita 75000.0 1 PMID:16673939 -3.2.1.8 * microbacterium trichothecenolyticum 41584.0 1 PMID:24861346 -3.2.1.8 * microcella alkaliphila 150000.0 1 PMID:27240670 -3.2.1.8 * mycothermus thermophilus 21000.0 2 * -3.2.1.8 * naganishia albida 48000.0 2 * -3.2.1.8 * neocallimastix patriciarum 36000.0 1 PMID:18415096 -3.2.1.8 * nesterenkonia xinjiangensis 26000.0 1 PMID:19838860 -3.2.1.8 * neurospora crassa 33000.0 2 PMID:16346591 -3.2.1.8 * niallia circulans 85000.0 3 * -3.2.1.8 * paecilomyces sp. 'thermophila' 28000.0 2 PMID:19759868 -3.2.1.8 * paecilomyces variotii 25000.0 1 PMID:10974122 -3.2.1.8 * paenibacillus campinasensis 41000.0 1 PMID:7765974 -3.2.1.8 * paenibacillus curdlanolyticus 142700.0 4 PMID:19349753;PMID:2105888;PMID:27663030 -3.2.1.8 * paenibacillus sp. 156700.0 3 PMID:18391461;PMID:25112314 -3.2.1.8 * parageobacillus thermantarcticus 45000.0 1 PMID:15142626 -3.2.1.8 * penicillium canescens 40000.0 1 PMID:23157299 -3.2.1.8 * penicillium citrinum 31600.0 5 PMID:16473771;PMID:17257262;PMID:18499053 -3.2.1.8 * penicillium griseofulvum 21300.0 3 PMID:17216454;PMID:19118652 -3.2.1.8 * penicillium occitanis (nom. inval.) 22000.0 2 * -3.2.1.8 * penicillium oxalicum 21300.0 1 PMID:23793944;PMID:24818699 -3.2.1.8 * penicillium sclerotiorum 33100.0 4 PMID:19680819 -3.2.1.8 * penicillium sp. cgmcc 1669 21500.0 1 PMID:19626289 -3.2.1.8 * phanerodontia chrysosporium 52000.0 6 PMID:15278289 -3.2.1.8 * phialophora sp. cgmcc 3328 55000.0 2 PMID:21120468 -3.2.1.8 * phlebia radiata 18600.0 2 PMID:11720306 -3.2.1.8 * pleurotus ostreatus 43000.0 2 PMID:30138852 -3.2.1.8 * pomacea insularus 47000.0 1 PMID:9145520 -3.2.1.8 * pomacea maculata 63000.0 1 PMID:18989576 -3.2.1.8 * pseudoalteromonas haloplanktis 45982.0 1 PMID:12089151 -3.2.1.8 * pseudobutyrivibrio xylanivorans 30000.0 1 * -3.2.1.8 * pseudothermotoga thermarum 40531.0 2 PMID:24170174 -3.2.1.8 * pseudozyma hubeiensis 33500.0 2 PMID:19692229 -3.2.1.8 * pyricularia grisea 47000.0 2 PMID:16461639 -3.2.1.8 * rasamsonia byssochlamydoides 76000.0 3 * -3.2.1.8 * rasamsonia emersonii 131000.0 3 * -3.2.1.8 * rhizomucor miehei 27000.0 1 PMID:21388922 -3.2.1.8 * rhizophlyctis rosea 31000.0 1 PMID:30397764 -3.2.1.8 * ruminiclostridium josui 85000.0 2 PMID:30037546 -3.2.1.8 * saccharolobus solfataricus 58800.0 4 PMID:15064978;PMID:18568289 -3.2.1.8 * saccharopolyspora pathumthaniensis 36000.0 1 PMID:21979072 -3.2.1.8 * schizophyllum commune 30500.0 4 PMID:23410928 -3.2.1.8 * streptomyces avermitilis 47000.0 3 PMID:18645964 -3.2.1.8 * streptomyces coelicolor 47000.0 2 PMID:26387816;PMID:27146990;PMID:27841749 -3.2.1.8 * streptomyces cyaneus 20500.0 1 PMID:17408951 -3.2.1.8 * streptomyces fradiae 47000.0 1 PMID:18388456 -3.2.1.8 * streptomyces griseorubens 45500.0 1 PMID:28919250 -3.2.1.8 * streptomyces ipomoeae 44000.0 1 PMID:30999191 -3.2.1.8 * streptomyces lividans 43000.0 1 PMID:3827815 -3.2.1.8 * streptomyces sp. 50000.0 12 PMID:10689075;PMID:14594403;PMID:22544563;PMID:22806794 -3.2.1.8 * streptomyces sp. s27 47000.0 4 PMID:19002659;PMID:19107475 -3.2.1.8 * streptomyces sp. s9 46000.0 1 PMID:18521591 -3.2.1.8 * streptomyces sp. tn119 38000.0 1 PMID:19412576 -3.2.1.8 * streptomyces thermocarboxydus 43962.0 1 * -3.2.1.8 * talaromyces funiculosus 64000.0 7 PMID:15450181;PMID:17216454;PMID:21466666 -3.2.1.8 * talaromyces pinophilus 51000.0 5 PMID:24211645 -3.2.1.8 * termitomyces clypeatus 90000.0 2 PMID:10467122;PMID:19728166;PMID:7189122 -3.2.1.8 * thermoascus aurantiacus 33000.0 3 * -3.2.1.8 * thermochaetoides thermophila 47000.0 6 PMID:19356131;PMID:29842954 -3.2.1.8 * thermoclostridium stercorarium 73000.0 8 PMID:7765283;PMID:7765974 -3.2.1.8 * thermoclostridium stercorarium subsp. thermolacticum 39000.0 1 PMID:2105888 -3.2.1.8 * thermomonospora sp. 38000.0 1 PMID:11263969 -3.2.1.8 * thermomyces dupontii 25000.0 1 PMID:18668373 -3.2.1.8 * thermomyces lanuginosus 75500.0 11 PMID:10467122;PMID:16243455;PMID:19078;PMID:19728166;PMID:23793944;PMID:24818699;PMID:29355625;PMID:9648252 -3.2.1.8 * thermothelomyces heterothallicus 25000.0 1 PMID:12932372 -3.2.1.8 * thermotoga maritima 120000.0 3 PMID:18083821 -3.2.1.8 * thermotoga petrophila 40000.0 1 PMID:22322560 -3.2.1.8 * trametes hirsuta 24000.0 1 PMID:27428 -3.2.1.8 * trichoderma harzianum 29000.0 2 * -3.2.1.8 * trichoderma longibrachiatum 37700.0 2 * -3.2.1.8 * trichoderma reesei 32000.0 8 PMID:11377763;PMID:17475200;PMID:17988729;PMID:19527524;PMID:19556747;PMID:20064285 -3.2.1.8 * trichoderma sp. 30100.0 2 PMID:19527927 -3.2.1.8 * trichoderma viride 21500.0 2 PMID:16667971 -3.2.1.8 * uncultured bacterium 80000.0 2 PMID:26358761 -3.2.1.8 * uncultured microorganism 60600.0 3 PMID:21455595;PMID:26719223 -3.2.1.80 * alternaria alternata 115000.0 1 PMID:12974403 -3.2.1.80 * arctium lappa 80000.0 2 PMID:21463533 -3.2.1.80 * asparagus officinalis 130000.0 1 PMID:29931209 -3.2.1.80 * aspergillus ficuum 63000.0 1 PMID:19127444 -3.2.1.80 * aspergillus fumigatus 200000.0 5 PMID:15126701 -3.2.1.80 * aspergillus niger 83000.0 1 PMID:15135402 -3.2.1.80 * avena sativa 43000.0 1 PMID:8742337 -3.2.1.80 * bacillus subtilis 200000.0 1 PMID:20801645 -3.2.1.80 * cichorium intybus 64000.0 3 PMID:11457968 -3.2.1.80 * hordeum vulgare 33000.0 1 * -3.2.1.80 * kluyveromyces marxianus 256000.0 3 PMID:21067917;PMID:32777449 -3.2.1.80 * lactiplantibacillus pentosus 126000.0 2 PMID:12086179 -3.2.1.80 * papiliotrema aurea 60000.0 1 PMID:18456943 -3.2.1.80 * penicillium janczewskii 80000.0 1 PMID:18065000 -3.2.1.80 * penicillium sp. 110000.0 4 PMID:12400688;PMID:17502268 -3.2.1.80 * phleum pratense 78000.0 2 PMID:21317211 -3.2.1.80 * streptococcus mutans 140000.0 2 PMID:1522814;PMID:3308844 -3.2.1.80 * streptococcus salivarius 85000.0 1 PMID:3965399 -3.2.1.80 * thermotoga maritima 50000.0 1 PMID:24128552 -3.2.1.80 * triticum aestivum 70000.0 2 PMID:12586886;PMID:16330524 -3.2.1.81 * acinetobacter sp. 100000.0 1 * -3.2.1.81 * agarivorans albus 50000.0 3 PMID:18071641;PMID:19349750;PMID:20161978 -3.2.1.81 * agarivorans sp. 109450.0 8 PMID:15307821;PMID:17028783;PMID:20161978;PMID:23221532 -3.2.1.81 * agarivorans sp. hz105 58000.0 2 PMID:19054239 -3.2.1.81 * agarivorans sp. lq48 51200.0 2 PMID:19484308 -3.2.1.81 * alteromonas sp. 180000.0 4 PMID:16232496;PMID:16317543;PMID:16348832 -3.2.1.81 * aquimarina sp. erc-38 46200.0 1 PMID:37002465 -3.2.1.81 * bacillus sp. (in: firmicutes) 113000.0 2 PMID:16233415;PMID:20161978 -3.2.1.81 * bacillus sp. mk03 113000.0 2 PMID:16233415;PMID:20161978 -3.2.1.81 * bacillus subtilis 20000.0 1 * -3.2.1.81 * cellvibrio sp. 79000.0 3 PMID:21030821;PMID:22814498 -3.2.1.81 * cellvibrio sp. ky-gh-1 63800.0 1 PMID:37145239 -3.2.1.81 * flammeovirga yaeyamensis 100000.0 3 PMID:21715227 -3.2.1.81 * flavobacterium flevense 26500.0 2 PMID:1083206;PMID:20161978 -3.2.1.81 * halococcus sp. 56000.0 2 PMID:23949137 -3.2.1.81 * microbulbifer elongatus 89900.0 3 PMID:34595592 -3.2.1.81 * microbulbifer sp. 65020.0 5 PMID:15088129;PMID:15170112;PMID:6617649 -3.2.1.81 * microbulbifer thermotolerans 49000.0 2 PMID:20161978 -3.2.1.81 * photobacterium gaetbulicola 106000.0 2 PMID:35866448 -3.2.1.81 * pseudoalteromonas antarctica 33000.0 1 PMID:9797294 -3.2.1.81 * pseudoalteromonas atlantica 55000.0 2 PMID:15170112;PMID:6617649 -3.2.1.81 * pseudoalteromonas sp. ag4 72500.0 2 PMID:20213114 -3.2.1.81 * pseudoalteromonas sp. cy24 50900.0 4 PMID:17166842;PMID:19504047 -3.2.1.81 * pseudomonas sp. 71000.0 7 PMID:20161978 -3.2.1.81 * pseudomonas-like bacterium 210000.0 7 PMID:718980 -3.2.1.81 * rhodococcus sp. q5 54000.0 1 * -3.2.1.81 * saccharophagus degradans 146000.0 5 PMID:11534834;PMID:19802606;PMID:20161978 -3.2.1.81 * saccharophagus degradans 2-40 87000.0 2 PMID:20161978 -3.2.1.81 * shewanella sp. enk2 50000.0 1 PMID:34436270 -3.2.1.81 * streptomyces coelicolor 35130.0 4 PMID:17165236;PMID:21655986;PMID:6489757 -3.2.1.81 * vibrio harveyi 50000.0 2 PMID:34436270 -3.2.1.81 * vibrio sp. 120000.0 14 PMID:16957270;PMID:17213669;PMID:17337564;PMID:17340109;PMID:18478285;PMID:20161978;PMID:21821738;PMID:8517750 -3.2.1.81 * vibrio sp. po-303 87500.0 2 PMID:20161978 -3.2.1.81 * vibrio sp. s1 33000.0 2 PMID:20161978 -3.2.1.81 * wenyingzhuangia aestuarii 80540.0 2 PMID:32578425 -3.2.1.81 * zobellia galactanivorans 539000.0 8 PMID:15456406;PMID:20161978;PMID:20213521 -3.2.1.82 * aspergillus niger 32000.0 1 PMID:18500582 -3.2.1.82 * bacillus sp. (in: firmicutes) 105000.0 1 PMID:11750764 -3.2.1.82 * dickeya chrysanthemi 68000.0 4 PMID:16346881;PMID:7056698 -3.2.1.82 * ralstonia solanacearum 79000.0 2 PMID:9393701 -3.2.1.82 * trametes sanguinea 42000.0 1 PMID:19781642 -3.2.1.83 * bacteria 40000.0 1 PMID:1915370 -3.2.1.83 * cellulophaga lytica 40800.0 1 PMID:24351836 -3.2.1.83 * colwellia echini 41300.0 1 PMID:37285044 -3.2.1.83 * cytophaga sp. 100000.0 2 PMID:3696007 -3.2.1.83 * microbulbifer elongatus 128000.0 1 * -3.2.1.83 * pedobacter hainanensis 55000.0 1 PMID:24606162 -3.2.1.83 * pseudoalteromonas carrageenovora 45000.0 2 PMID:25281802;PMID:33808;PMID:7737202 -3.2.1.83 * pseudoalteromonas porphyrae 40000.0 1 PMID:1915370 -3.2.1.83 * pseudoalteromonas sp. 35000.0 1 PMID:33808;PMID:7737202 -3.2.1.83 * pseudoalteromonas sp. zdy3 44997.0 2 PMID:33035660 -3.2.1.83 * pseudoalteromonas tetraodonis 85000.0 2 PMID:22451392 -3.2.1.83 * pseudomonas carrageenovora 35000.0 1 PMID:33808;PMID:7737202 -3.2.1.83 * tamlana sp. 66400.0 1 * -3.2.1.83 * zobellia sp. m-2 37300.0 1 PMID:24196580 -3.2.1.83 * zobellia sp. zl-4 66000.0 2 PMID:30794899 -3.2.1.84 * amorphotheca resinae 88000.0 1 * -3.2.1.84 * aspergillus nidulans 48000.0 2 PMID:11728159;PMID:4622000 -3.2.1.84 * paenibacillus sp. 135000.0 1 PMID:18326674 -3.2.1.84 * sulfolobus acidocaldarius 914000.0 3 PMID:23396915 -3.2.1.84 * trichoderma harzianum 72000.0 4 PMID:11722942;PMID:23520578 -3.2.1.84 * trichoderma sp. 47000.0 1 * -3.2.1.85 * bacillus amyloliquefaciens 113000.0 3 PMID:33144261 -3.2.1.85 * geobacillus stearothermophilus 115000.0 2 PMID:24637762;PMID:28975708 -3.2.1.85 * lacticaseibacillus casei 130000.0 3 PMID:3130295;PMID:5057373;PMID:6292163 -3.2.1.85 * lactobacillus gasseri 58000.0 2 PMID:22449746;PMID:8824835 -3.2.1.85 * lactococcus cremoris 67600.0 1 PMID:4204438 -3.2.1.85 * lactococcus lactis 58000.0 2 PMID:3086494;PMID:3130294 -3.2.1.85 * leptotrichia buccalis 53000.0 1 PMID:12351228 -3.2.1.85 * staphylococcus aureus 53000.0 2 PMID:237202;PMID:5447434 -3.2.1.85 * streptococcus mutans 40000.0 1 PMID:33899 -3.2.1.86 * escherichia coli 142000.0 6 PMID:10572139;PMID:4607165 -3.2.1.86 * fusobacterium mortiferum 54000.0 3 PMID:9045824 -3.2.1.86 * geobacillus stearothermophilus 115000.0 1 PMID:28975708 -3.2.1.86 * klebsiella aerogenes 52000.0 1 PMID:237203;PMID:4624114 -3.2.1.86 * lactobacillus gasseri 55000.0 1 PMID:22449746 -3.2.1.86 * oenococcus oeni 55000.0 1 * -3.2.1.86 * pectobacterium carotovorum 53000.0 1 PMID:15748978 -3.2.1.87 * acinetobacter phage vb_abap_b3 55200.0 1 PMID:31227554 -3.2.1.87 * acinetobacter phage vb_abap_pmk34 76000.0 1 PMID:35625321 -3.2.1.87 * klebsiella aerogenes 379000.0 5 PMID:5096084 -3.2.1.87 * klebsiella phage kp32 259500.0 2 PMID:30405575 -3.2.1.88 * cajanus indicus 25900.0 1 PMID:4699248 -3.2.1.89 * aspergillus aculeatus 44000.0 5 PMID:10852969 -3.2.1.89 * aspergillus niger 48500.0 4 PMID:12383257;PMID:8520117 -3.2.1.89 * aspergillus sojae 39700.0 1 * -3.2.1.89 * bacillus sp. (in: firmicutes) 36000.0 1 * -3.2.1.89 * bacillus subtilis 37000.0 4 * -3.2.1.89 * bacillus subtilis subsp. subtilis 51200.0 4 PMID:36280173 -3.2.1.89 * fusarium sambucinum 67000.0 1 * -3.2.1.89 * penicillium chrysogenum 78000.0 2 PMID:22584433 -3.2.1.89 * penicillium citrinum 35000.0 1 * -3.2.1.89 * sclerotinia sclerotiorum 24000.0 1 * -3.2.1.89 * thermotoga maritima 64000.0 1 PMID:16495677 -3.2.1.91 * acetivibrio thermocellus 79000.0 1 * -3.2.1.91 * agroathelia rolfsii 42000.0 1 * -3.2.1.91 * aspergillus niger 52500.0 1 * -3.2.1.91 * bacillus sp. cf96 35600.0 1 PMID:30904535 -3.2.1.91 * caldicellulosiruptor saccharolyticus 120000.0 1 PMID:2126700 -3.2.1.91 * cellulomonas fimi 58000.0 1 PMID:6432782 -3.2.1.91 * cellulomonas uda 81000.0 1 * -3.2.1.91 * chrysosporium lucknowense 70000.0 2 PMID:17221887 -3.2.1.91 * coprinopsis cinerea 48951.0 2 PMID:19194005 -3.2.1.91 * fibrobacter succinogenes 75000.0 2 PMID:16347334;PMID:3384799 -3.2.1.91 * fomitopsis pinicola 64000.0 1 PMID:21193824 -3.2.1.91 * fusarium oxysporum 57000.0 2 * -3.2.1.91 * halorhabdus utahensis 90000.0 2 * -3.2.1.91 * irpex lacteus 65000.0 5 PMID:19060394 -3.2.1.91 * neocallimastix patriciarum 53950.0 1 PMID:23770555 -3.2.1.91 * niallia circulans 60000.0 1 * -3.2.1.91 * orpinomyces sp. 51500.0 1 PMID:25164344 -3.2.1.91 * penicillium chrysogenum 56000.0 1 PMID:17277884 -3.2.1.91 * penicillium sp. 64000.0 1 PMID:21193824 -3.2.1.91 * ruminococcus albus 200000.0 2 PMID:7061402 -3.2.1.91 * ruminococcus flavefaciens 230000.0 2 PMID:3115960 -3.2.1.91 * saccharophagus degradans 81900.0 1 PMID:16707677 -3.2.1.91 * talaromyces funiculosus 46300.0 1 PMID:7458906 -3.2.1.91 * talaromyces pinophilus 50700.0 2 * -3.2.1.91 * talaromyces purpureogenus 84000.0 4 PMID:20582640 -3.2.1.91 * thermochaetoides thermophila 62000.0 1 PMID:2597698 -3.2.1.91 * thermoclostridium stercorarium 87000.0 1 PMID:1909625 -3.2.1.91 * thermothelomyces thermophilus 63750.0 2 PMID:34735642 -3.2.1.91 * thermothielavioides terrestris 54000.0 1 PMID:26830095 -3.2.1.91 * thermotoga sp. 22000.0 1 PMID:1872819 -3.2.1.91 * trichoderma reesei 68000.0 4 PMID:22638966 -3.2.1.91 * trichoderma viride 46000.0 2 PMID:4738092 -3.2.1.91 * uncultured bacterium 42000.0 1 PMID:33482202 -3.2.1.92 * bacillus subtilis 90000.0 1 PMID:6281 -3.2.1.93 * uncultured bacterium 65000.0 2 PMID:32733411 -3.2.1.94 * arthrobacter dextranolyticus 65990.0 2 PMID:15248038 -3.2.1.94 * arthrobacter globiformis 69000.0 3 PMID:15200177 -3.2.1.95 * brevibacterium fuscum 68000.0 1 PMID:10540747 -3.2.1.96 * acinetobacter sp. 35000.0 1 * -3.2.1.96 * aspergillus oryzae 31000.0 1 PMID:3934149 -3.2.1.96 * bacillus sp. (in: firmicutes) 210000.0 4 * -3.2.1.96 * bacillus subtilis 190000.0 2 PMID:6150066 -3.2.1.96 * bifidobacterium longum subsp. infantis 53000.0 2 PMID:22745059 -3.2.1.96 * bifidobacterium longum subsp. longum 98000.0 1 PMID:22745059 -3.2.1.96 * elizabethkingia meningoseptica 39500.0 3 PMID:8525060 -3.2.1.96 * ficus carica 52000.0 2 PMID:6793075 -3.2.1.96 * flavobacterium sp. 30000.0 4 PMID:11515537;PMID:8525060 -3.2.1.96 * gallus gallus 56000.0 3 PMID:661601;PMID:9498561;PMID:977586 -3.2.1.96 * glutamicibacter protophormiae 72000.0 1 PMID:9015383 -3.2.1.96 * glycine max 62000.0 1 PMID:9659369 -3.2.1.96 * halalkalibacterium halodurans 90000.0 1 PMID:15170110 -3.2.1.96 * hevea brasiliensis 100000.0 1 PMID:22318728;PMID:24833032 -3.2.1.96 * homo sapiens 55000.0 1 PMID:12114544 -3.2.1.96 * lathyrus oleraceus 42000.0 2 PMID:9063968 -3.2.1.96 * mucor hiemalis 95000.0 2 PMID:1368528 -3.2.1.96 * ogataea minuta 91000.0 2 PMID:23436287 -3.2.1.96 * oryza sativa japonica group 70000.0 1 PMID:34447396 -3.2.1.96 * pseudomonas sp. 106000.0 2 PMID:1776950 -3.2.1.96 * rhizomucor pusillus 78900.0 1 PMID:35961816 -3.2.1.96 * solanum lycopersicum 62000.0 1 PMID:9659369 -3.2.1.96 * stigmatella aurantiaca 27000.0 1 PMID:7928985;PMID:8525060 -3.2.1.96 * streptococcus pneumoniae 280000.0 7 PMID:11388907;PMID:21505233;PMID:22318728;PMID:24833032;PMID:2492193;PMID:26846;PMID:75885 -3.2.1.96 * streptomyces griseus 27200.0 2 PMID:4204552 -3.2.1.96 * streptomyces plicatus 49500.0 6 PMID:24599668;PMID:26849;PMID:489563;PMID:7928985;PMID:8525060 -3.2.1.96 * trichoderma viride 35000.0 1 PMID:22373601 -3.2.1.97 * [clostridium] nexile 240000.0 1 PMID:32169671 -3.2.1.97 * alcaligenes sp. 160000.0 1 PMID:21877 -3.2.1.97 * bacillus sp. (in: firmicutes) 110000.0 1 PMID:10620364 -3.2.1.97 * bifidobacterium longum 210300.0 4 PMID:16141207;PMID:16233817 -3.2.1.97 * brevibacillus laterosporus 210000.0 2 * -3.2.1.97 * clostridium perfringens 187800.0 1 PMID:31987726 -3.2.1.97 * enterococcus faecalis 150000.0 1 PMID:18725192 -3.2.1.97 * streptococcus pneumoniae 190000.0 2 PMID:21877;PMID:21878 -3.2.1.97 * streptomyces sp. 105000.0 1 PMID:1281406 -3.2.1.98 * bacillus sp. h-167 102600.0 6 PMID:2227348 -3.2.1.98 * bacillus subtilis 60000.0 1 * -3.2.1.98 * corallococcus sp. egb 55460.0 2 PMID:25576603 -3.2.1.98 * klebsiella pneumoniae 75921.0 6 PMID:10737206;PMID:1094;PMID:15583388 -3.2.1.98 * niallia circulans 76000.0 1 * -3.2.1.98 * streptomyces sp. 36920.0 2 * -3.2.1.99 * aspergillus aculeatus 45000.0 1 * -3.2.1.99 * aspergillus nidulans 40000.0 1 PMID:8243977 -3.2.1.99 * aspergillus niger 45000.0 7 PMID:11916679;PMID:11999422;PMID:15159584;PMID:1814275;PMID:7764386;PMID:8243977 -3.2.1.99 * bacillus licheniformis 46769.0 6 PMID:23274993;PMID:25801671;PMID:29800670 -3.2.1.99 * bacillus subtilis 52380.0 8 PMID:15556708;PMID:16660741;PMID:18408032;PMID:9183009 -3.2.1.99 * caldicellulosiruptor saccharolyticus dsm 8903 112000.0 2 PMID:19458916 -3.2.1.99 * cellulomonas sp. 45000.0 1 PMID:22120088 -3.2.1.99 * geobacillus thermodenitrificans 35280.0 3 PMID:11916679;PMID:11999422;PMID:15159584 -3.2.1.99 * lactobacillus crispatus 72110.0 2 PMID:33119797 -3.2.1.99 * paenibacillus polymyxa 35477.0 1 PMID:25077565 -3.2.1.99 * penicillium chrysogenum 31000.0 2 PMID:21748379 -3.2.1.99 * phanerodontia chrysosporium 33900.0 2 PMID:23361183 -3.2.1.99 * pseudomonas fluorescens 39440.0 2 PMID:9163351 -3.2.1.99 * pseudothermotoga thermarum 36000.0 1 PMID:24886412 -3.2.1.99 * talaromyces purpureogenus 38000.0 2 PMID:29197821 -3.2.1.99 * thermotoga petrophila 49000.0 1 PMID:20678476 -3.2.2.1 * aedes aegypti 51500.0 1 PMID:12459196 -3.2.2.1 * bacillus thuringiensis 36200.0 1 PMID:18451042 -3.2.2.1 * brucella anthropi 172000.0 2 PMID:11282633 -3.2.2.1 * caenorhabditis elegans 38000.0 1 PMID:12777783 -3.2.2.1 * campylobacter jejuni 39000.0 1 PMID:12777783 -3.2.2.1 * corynebacterium ammoniagenes 35892.0 2 PMID:16549679 -3.2.2.1 * crithidia fasciculata 143000.0 2 PMID:1939115 -3.2.2.1 * giardia duodenalis 40000.0 1 PMID:18048928 -3.2.2.1 * lathyrus oleraceus 49000.0 3 PMID:30366031 -3.2.2.1 * leishmania major 35600.0 1 PMID:17141482 -3.2.2.1 * leishmania mexicana 205000.0 1 PMID:468819 -3.2.2.1 * lentilactobacillus buchneri 130000.0 1 PMID:27180876 -3.2.2.1 * saccharolobus solfataricus 68650.0 3 PMID:19121283 -3.2.2.1 * salmonella enterica 142000.0 3 PMID:15784179 -3.2.2.1 * trypanosoma brucei 71000.0 3 PMID:8702965 -3.2.2.1 * vigna unguiculata 160000.0 2 * -3.2.2.11 * lymnaea stagnalis 40000.0 1 * -3.2.2.13 * patiria pectinifera 96000.0 1 PMID:4635890 -3.2.2.14 * azotobacter vinelandii 240000.0 4 PMID:3571198;PMID:457634 -3.2.2.14 * salmonella enterica subsp. enterica serovar typhimurium 67000.0 1 PMID:6109709 -3.2.2.15 * bos taurus 31000.0 1 PMID:1861976;PMID:7193480 -3.2.2.15 * escherichia coli 30000.0 1 PMID:98523 -3.2.2.15 * homo sapiens 37000.0 1 PMID:2079960 -3.2.2.16 * acetabularia acetabulum 46000.0 1 * -3.2.2.16 * arabidopsis thaliana 28000.0 1 PMID:18945934 -3.2.2.16 * brucella melitensis 25000.0 1 PMID:24657441 -3.2.2.16 * burkholderia thailandensis 34000.0 1 PMID:23198993 -3.2.2.16 * escherichia coli 31000.0 3 PMID:11134941;PMID:22239413 -3.2.2.16 * glycine max 180000.0 2 * -3.2.2.16 * homo sapiens 95000.0 2 PMID:631411 -3.2.2.16 * lupinus luteus 62000.0 2 PMID:6783408 -3.2.2.17 * lysinibacillus sphaericus 26000.0 1 PMID:10844244 -3.2.2.17 * micrococcus luteus 18000.0 2 PMID:7142160;PMID:9582353 -3.2.2.17 * paramecium bursaria chlorella virus 1 16000.0 1 PMID:6277906;PMID:9582353 -3.2.2.17 * tequatrovirus t4 26000.0 3 PMID:6265906;PMID:6270375;PMID:7142160 -3.2.2.19 * bos taurus 39000.0 1 PMID:1375222;PMID:9193633 -3.2.2.19 * gallus gallus 40000.0 1 PMID:2382826 -3.2.2.19 * homo sapiens 111000.0 2 PMID:1375222;PMID:22767504;PMID:8349667 -3.2.2.19 * meleagris gallopavo 40000.0 3 PMID:1375222;PMID:3179279;PMID:3778868;PMID:7898453;PMID:9193633 -3.2.2.19 * mus musculus 39000.0 2 PMID:1375222;PMID:9037477;PMID:9193633 -3.2.2.19 * oryctolagus cuniculus 40000.0 1 PMID:2382826 -3.2.2.19 * rattus norvegicus 40000.0 4 PMID:1375222;PMID:2382826;PMID:8349667;PMID:9037477;PMID:9193633 -3.2.2.2 * azotobacter vinelandii 70000.0 1 PMID:19121283;PMID:31149 -3.2.2.2 * lupinus luteus 80000.0 2 PMID:16662492;PMID:16820181 -3.2.2.2 * saccharolobus solfataricus 70000.0 2 PMID:19121283;PMID:31149 -3.2.2.20 * bacillus cereus 28000.0 1 PMID:16468998 -3.2.2.20 * escherichia coli 22500.0 6 PMID:10679272;PMID:352392;PMID:3550703;PMID:7040983;PMID:7041972 -3.2.2.20 * leptospira interrogans 22703.0 1 * -3.2.2.20 * micrococcus luteus 22000.0 1 PMID:3628000 -3.2.2.21 * archaeoglobus fulgidus 40000.0 2 PMID:12379112 -3.2.2.21 * bacillus cereus 25000.0 1 PMID:16468998 -3.2.2.21 * escherichia coli 31400.0 3 PMID:3065516;PMID:7040983;PMID:7041972;PMID:8895496;PMID:8941728 -3.2.2.21 * homo sapiens 33000.0 2 PMID:18191412;PMID:9684856 -3.2.2.21 * micrococcus luteus 22000.0 1 PMID:3628000 -3.2.2.22 * abelmoschus esculentus 30000.0 1 PMID:19727528;PMID:22361570 -3.2.2.22 * abrus precatorius 30000.0 1 PMID:15194237 -3.2.2.22 * adenia volkensii 60000.0 3 PMID:16997573 -3.2.2.22 * arabidopsis thaliana 62000.0 3 PMID:18222123 -3.2.2.22 * aralia elata 32000.0 2 PMID:15493877 -3.2.2.22 * benincasa hispida 21000.0 1 PMID:12406674;PMID:12948831 -3.2.2.22 * bougainvillea buttiana 78000.0 4 PMID:18376074 -3.2.2.22 * celosia argentea var. plumosa 25000.0 1 PMID:30804646 -3.2.2.22 * cinnamomum camphora 61000.0 7 PMID:11722556;PMID:7548157;PMID:9894808 -3.2.2.22 * cinnamomum parthenoxylon 64500.0 4 PMID:8997493 -3.2.2.22 * corynebacterium diphtheriae 40000.0 2 PMID:21549738 -3.2.2.22 * cucurbita pepo 26000.0 1 PMID:9022685 -3.2.2.22 * escherichia coli 35000.0 4 PMID:20629887;PMID:21184769;PMID:24097977 -3.2.2.22 * gypsophila elegans 28000.0 1 PMID:17329832;PMID:7737197;PMID:9058971 -3.2.2.22 * gypsophila vaccaria 28000.0 2 PMID:17329832;PMID:7737197;PMID:9058971 -3.2.2.22 * hordeum vulgare 60000.0 1 PMID:11427481 -3.2.2.22 * hypsizygus marmoreus 10000.0 2 PMID:18751697 -3.2.2.22 * lathyrus oleraceus 20500.0 2 PMID:9875233 -3.2.2.22 * luffa aegyptiaca 21000.0 3 PMID:12406674;PMID:12948831 -3.2.2.22 * momordica balsamina 30000.0 2 PMID:19727528;PMID:22120616;PMID:22361570 -3.2.2.22 * momordica charantia 31000.0 4 PMID:19727528;PMID:22262229;PMID:22361570 -3.2.2.22 * momordica cochinchinensis 31000.0 3 PMID:17329832;PMID:2597699;PMID:7737197;PMID:9058971 -3.2.2.22 * nicotiana tabacum 26000.0 1 PMID:14671015 -3.2.2.22 * phytolacca americana 31000.0 3 PMID:3342056 -3.2.2.22 * phytolacca dioica 31560.0 2 PMID:19014994 -3.2.2.22 * ricinus communis 62925.0 8 PMID:16518777;PMID:18266157;PMID:19292477;PMID:22909382;PMID:25576235 -3.2.2.22 * saccharina japonica 36000.0 1 PMID:12354105 -3.2.2.22 * sambucus nigra 24100.0 2 PMID:9645479 -3.2.2.22 * sambucus sieboldiana 61000.0 4 PMID:9143320 -3.2.2.22 * saponaria ocymoides 30200.0 1 PMID:7737197 -3.2.2.22 * saponaria officinalis 31600.0 6 PMID:18164211;PMID:3342056;PMID:8218413 -3.2.2.22 * siraitia grosvenorii 27700.0 1 PMID:11205869 -3.2.2.22 * trichosanthes anguina 35000.0 1 * -3.2.2.22 * trichosanthes kirilowii 13000.0 1 PMID:19303444 -3.2.2.22 * trichosanthes lepiniate 24670.0 1 PMID:10205663 -3.2.2.22 * trichosanthes sp. 27000.0 1 PMID:11592913 -3.2.2.22 * viscum album 66000.0 4 PMID:15023051;PMID:15535979 -3.2.2.22 * ximenia americana 31000.0 2 PMID:24699434 -3.2.2.23 * arabidopsis thaliana 46000.0 4 PMID:11272725 -3.2.2.23 * deinococcus radiodurans 34800.0 1 PMID:10413519 -3.2.2.23 * escherichia coli 62900.0 9 PMID:10671534;PMID:10744666;PMID:21356311;PMID:23607987;PMID:24498234;PMID:3319582;PMID:7028101;PMID:7744806;PMID:9125531;PMID:9826758 -3.2.2.23 * homo sapiens 43582.0 3 PMID:10671534;PMID:11904416;PMID:21356311;PMID:23607987 -3.2.2.23 * lactococcus lactis 31300.0 2 PMID:7704272 -3.2.2.23 * mycobacterium tuberculosis 32000.0 2 PMID:19496823 -3.2.2.24 * rhodospirillum rubrum 32000.0 1 PMID:23144248;PMID:23574616 -3.2.2.25 * camellia sinensis 55000.0 1 * -3.2.2.26 * thermus thermophilus 220000.0 3 PMID:19420717 -3.2.2.27 * archaeoglobus fulgidus 27000.0 2 PMID:11738943;PMID:20453094 -3.2.2.27 * bacillus sp. (in: firmicutes) 27218.0 2 PMID:18626641 -3.2.2.27 * caenorhabditis elegans 60000.0 3 PMID:18524757;PMID:20493785 -3.2.2.27 * deinococcus radiodurans 27700.0 1 PMID:16041069 -3.2.2.27 * drosophila melanogaster 60000.0 1 PMID:12711670 -3.2.2.27 * gadus morhua 25000.0 1 PMID:11126771 -3.2.2.27 * methanocaldococcus jannaschii 24000.0 1 PMID:12682355;PMID:19004346 -3.2.2.27 * monkeypox virus 27604.0 1 PMID:17910420 -3.2.2.27 * mycobacterium tuberculosis 28500.0 1 PMID:20031487 -3.2.2.27 * mycolicibacterium smegmatis 25000.0 1 PMID:11399761;PMID:9780234 -3.2.2.27 * orthopoxvirus vaccinia 57000.0 2 PMID:17605817;PMID:23519808 -3.2.2.27 * pyrobaculum aerophilum 28000.0 2 PMID:11399761;PMID:12065430;PMID:9780234 -3.2.2.27 * schizosaccharomyces pombe 37000.0 1 PMID:12711670 -3.2.2.27 * thermoplasma acidophilum 25601.0 2 PMID:21665970 -3.2.2.27 * thermotoga maritima 20578.0 1 PMID:11267830 -3.2.2.27 * xenopus laevis 31000.0 1 PMID:10074426 -3.2.2.28 * escherichia coli 18670.0 1 PMID:10956012 -3.2.2.29 * drosophila melanogaster 60000.0 1 PMID:12711670 -3.2.2.29 * homo sapiens 60000.0 4 PMID:12711670;PMID:8127859;PMID:8407958;PMID:8662714 -3.2.2.29 * pyrobaculum aerophilum 27900.0 1 PMID:10671447 -3.2.2.3 * escherichia coli 69000.0 3 PMID:24473221 -3.2.2.3 * hordeum vulgare 117000.0 2 * -3.2.2.3 * lathyrus oleraceus 55000.0 1 * -3.2.2.3 * limosilactobacillus reuteri 33380.0 1 PMID:38203708 -3.2.2.3 * saccharomyces cerevisiae 32500.0 4 PMID:237897;PMID:357896;PMID:4944454 -3.2.2.30 * arabidopsis thaliana 27462.0 1 PMID:18342331 -3.2.2.4 * azotobacter vinelandii 370000.0 13 PMID:2670945;PMID:2690948;PMID:4781054;PMID:5041898;PMID:5118623;PMID:5472347;PMID:6251048;PMID:632260;PMID:6796578 -3.2.2.4 * escherichia coli 520000.0 6 PMID:2670945;PMID:3533942;PMID:7000783 -3.2.2.5 * aliivibrio fischeri 32000.0 1 PMID:11114931 -3.2.2.5 * aplysia californica 29000.0 1 PMID:1650254 -3.2.2.5 * aspergillus fumigatus 40000.0 2 PMID:33712585 -3.2.2.5 * bacillus subtilis 26200.0 2 PMID:170869;PMID:6246385;PMID:6279 -3.2.2.5 * bos taurus 36300.0 3 PMID:170869;PMID:2986595;PMID:6246386;PMID:6279 -3.2.2.5 * bungarus fasciatus 125000.0 2 PMID:3010034;PMID:6260772 -3.2.2.5 * deinagkistrodon acutus 100000.0 6 PMID:12135566;PMID:18952139;PMID:2845606 -3.2.2.5 * homo sapiens 49000.0 1 PMID:14741735 -3.2.2.5 * microdochium nivale 27000.0 1 PMID:4144238 -3.2.2.5 * micrurus surinamensis 34206.0 1 PMID:30755823 -3.2.2.5 * neurospora crassa 36500.0 2 PMID:170869 -3.2.2.5 * oryctolagus cuniculus 63000.0 3 PMID:24759100;PMID:8393643 -3.2.2.5 * rattus norvegicus 83000.0 1 PMID:31183 -3.2.2.5 * streptococcus pyogenes 55000.0 2 PMID:236282;PMID:23689507 -3.2.2.5 * streptococcus pyogenes serotype m3 49000.0 1 PMID:24121349 -3.2.2.5 * streptococcus sp. 55000.0 1 PMID:11967084 -3.2.2.5 * vibrio cholerae serotype o1 29000.0 1 PMID:225325 -3.2.2.6 * homo sapiens 45000.0 3 PMID:10825668;PMID:23946809 -3.2.2.6 * pseudomonas putida kb1 23500.0 1 PMID:4345853 -3.2.2.6 * saccharomyces cerevisiae 50000.0 2 * -3.2.2.6 * streptomyces griseus 1600000.0 1 * -3.2.2.6 * xenopus laevis 45000.0 2 PMID:22422046 -3.2.2.7 * camellia sinensis 68000.0 1 * -3.2.2.7 * coffea arabica 72000.0 2 PMID:15652571 -3.2.2.7 * hordeum vulgare 120000.0 3 PMID:861230 -3.2.2.7 * lupinus luteus 72000.0 1 PMID:15652571 -3.2.2.7 * solanum lycopersicum 68000.0 1 * -3.2.2.7 * solanum tuberosum 62400.0 1 * -3.2.2.7 * triticum aestivum 59000.0 1 PMID:16662043 -3.2.2.8 * escherichia coli 143000.0 3 PMID:15130467 -3.2.2.8 * escherichia coli k-12 143000.0 2 PMID:14993681 -3.2.2.8 * lathyrus oleraceus 62000.0 1 * -3.2.2.8 * leishmania braziliensis 136000.0 1 * -3.2.2.8 * leishmania donovani 180000.0 1 PMID:468819 -3.2.2.8 * saccharolobus solfataricus 140000.0 3 PMID:18355316 -3.2.2.9 * arabidopsis thaliana 28000.0 2 PMID:18342331;PMID:20345605 -3.2.2.9 * borreliella burgdorferi 32000.0 4 PMID:15501754;PMID:31669585 -3.2.2.9 * brucella melitensis 25000.0 1 PMID:24657441 -3.2.2.9 * burkholderia thailandensis 34000.0 1 PMID:23198993 -3.2.2.9 * escherichia coli 31000.0 5 PMID:22239413;PMID:782530;PMID:9524204 -3.2.2.9 * klebsiella pneumoniae 26500.0 2 PMID:8694776 -3.3.2.1 * escherichia coli 159000.0 5 PMID:16632253;PMID:2139796;PMID:3040680 -3.3.2.1 * homo sapiens 23000.0 1 PMID:17658461 -3.3.2.1 * microbacterium hydrocarbonoxydans 40000.0 4 PMID:25341397 -3.3.2.1 * vibrio anguillarum 32400.0 1 PMID:11073922 -3.3.2.10 * ananas comosus 35000.0 1 PMID:15748653 -3.3.2.10 * apium graveolens 35000.0 1 PMID:15748653 -3.3.2.10 * arabidopsis thaliana 40000.0 5 PMID:10860549;PMID:12356472;PMID:15748653 -3.3.2.10 * aspergillus niger 185000.0 3 PMID:10406946 -3.3.2.10 * brassica napus 45000.0 3 PMID:12392563;PMID:15748653 -3.3.2.10 * cavia porcellus 62000.0 2 PMID:15748653;PMID:2925635;PMID:3277731 -3.3.2.10 * citrus jambhiri 35000.0 1 PMID:15748653 -3.3.2.10 * corynebacterium sp. 340000.0 2 PMID:9578475 -3.3.2.10 * cress 40000.0 2 PMID:10860549 -3.3.2.10 * danio rerio 64800.0 1 * -3.3.2.10 * equus caballus 62000.0 1 PMID:15748653 -3.3.2.10 * euphorbia lagascae 35000.0 1 PMID:15748653 -3.3.2.10 * gallus gallus 63000.0 1 PMID:16523628 -3.3.2.10 * glycine max 64200.0 6 PMID:10785386;PMID:1554352;PMID:15748653 -3.3.2.10 * homo sapiens 140000.0 16 PMID:10860549;PMID:15748653;PMID:15822179;PMID:18383502;PMID:18729246;PMID:18775727;PMID:19519461;PMID:20079692;PMID:20433684;PMID:2272333;PMID:23362272;PMID:2347424;PMID:23701967;PMID:3046942;PMID:3856846;PMID:3996389;PMID:6185139;PMID:6847673 -3.3.2.10 * macaca mulatta 62000.0 1 PMID:15748653 -3.3.2.10 * malus pumila 35000.0 1 PMID:15748653 -3.3.2.10 * mammalia 62000.0 1 PMID:19519461;PMID:20079692;PMID:20433684 -3.3.2.10 * mesocricetus auratus 62000.0 1 PMID:15748653 -3.3.2.10 * mus musculus 130000.0 16 PMID:10860549;PMID:15700109;PMID:15748653;PMID:1910279;PMID:19519461;PMID:20079692;PMID:20433684;PMID:2272333;PMID:2347424;PMID:2925635;PMID:3046942;PMID:3277731;PMID:3856846;PMID:3947062;PMID:3996389;PMID:6847673 -3.3.2.10 * nicotiana tabacum 35000.0 1 PMID:15748653 -3.3.2.10 * oryctolagus cuniculus 110000.0 3 PMID:15748653;PMID:7117244 -3.3.2.10 * oryza sativa 35000.0 1 PMID:15748653 -3.3.2.10 * papio sp. 62000.0 1 PMID:15748653 -3.3.2.10 * rattus norvegicus 130000.0 8 PMID:10860549;PMID:14737000;PMID:15748653;PMID:18711743;PMID:2272333;PMID:3046942;PMID:3996389;PMID:6185139 -3.3.2.10 * ricinus communis 35000.0 1 PMID:15748653 -3.3.2.10 * solanum tuberosum 40000.0 5 PMID:10860549;PMID:15748653;PMID:7920715 -3.3.2.10 * spinacia oleracea 35000.0 1 PMID:15748653 -3.3.2.10 * strongylocentrotus purpuratus 64200.0 2 PMID:18554159 -3.3.2.10 * sus scrofa 62000.0 1 PMID:15748653 -3.3.2.10 * trichoderma reesei 38200.0 1 PMID:27177457 -3.3.2.10 * triticum aestivum 35000.0 1 PMID:15748653 -3.3.2.10 * vicia sativa 35000.0 1 PMID:15748653 -3.3.2.12 * escherichia coli 73045.0 1 PMID:9748275 -3.3.2.14 * nocardioides sp. 265000.0 4 PMID:25281383 -3.3.2.15 * pseudomonas aeruginosa 49400.0 3 PMID:12741825 -3.3.2.15 * pseudomonas fluorescens 23074.0 1 PMID:9573209 -3.3.2.2 * legionella pneumophila 18000.0 1 PMID:25445671 -3.3.2.2 * rattus norvegicus 19000.0 1 PMID:21515882 -3.3.2.4 * pseudomonas putida 66300.0 1 PMID:5782001 -3.3.2.6 * cavia porcellus 70000.0 4 PMID:2722767;PMID:3391178;PMID:7665088;PMID:7843421;PMID:9738935 -3.3.2.6 * homo sapiens 70000.0 8 PMID:17517102;PMID:18394906;PMID:1932096;PMID:23220644;PMID:2722767;PMID:3038871;PMID:6490615;PMID:7843421;PMID:7946391;PMID:8615763;PMID:9738935;PMID:9744798 -3.3.2.6 * mus musculus 69000.0 1 PMID:1932096;PMID:23220644;PMID:9744798 -3.3.2.6 * rattus norvegicus 69000.0 3 PMID:1544505;PMID:3995081 -3.3.2.6 * saccharomyces cerevisiae 72000.0 1 PMID:10574934 -3.3.2.6 * xenopus laevis 70000.0 2 PMID:1932096;PMID:23220644;PMID:2722767;PMID:7843421;PMID:9738935;PMID:9744798 -3.3.2.7 * rattus norvegicus 53000.0 1 PMID:2722835 -3.3.2.8 * rhodococcus erythropolis 17000.0 3 PMID:9748436;PMID:9827564 -3.3.2.9 * apium graveolens 62000.0 2 PMID:12020347 -3.3.2.9 * heliothis virescens 53129.0 1 PMID:23276675 -3.3.2.9 * homalodisca vitripennis 52108.0 2 PMID:23704009 -3.3.2.9 * homo sapiens 130000.0 8 PMID:109443;PMID:1227945;PMID:14737000;PMID:15748653;PMID:20383792;PMID:23564882;PMID:3082328;PMID:4075436;PMID:500710;PMID:507823;PMID:6185139;PMID:6316;PMID:7329313;PMID:8396141;PMID:9692241 -3.3.2.9 * manduca sexta 50000.0 1 PMID:14737000;PMID:3082328;PMID:500710;PMID:6185139;PMID:8396141;PMID:9692241 -3.3.2.9 * mugil cephalus 49800.0 1 PMID:17151961 -3.3.2.9 * mus musculus 130000.0 3 PMID:18622027;PMID:18711743;PMID:409633;PMID:869931 -3.3.2.9 * phanerodontia chrysosporium 42000.0 1 PMID:19657565 -3.3.2.9 * rattus norvegicus 800000.0 6 PMID:109443;PMID:1227945;PMID:14737000;PMID:18622027;PMID:18711743;PMID:3082328;PMID:409633;PMID:500710;PMID:507823;PMID:6185139;PMID:6316;PMID:7329313;PMID:8396141;PMID:869931;PMID:9692241 -3.3.2.9 * zea mays 64000.0 1 PMID:12020347 -3.4.11.1 * acinetobacter calcoaceticus 400000.0 1 PMID:8229672 -3.4.11.1 * aquifex aeolicus 54000.0 1 PMID:10672029;PMID:10862905 -3.4.11.1 * arabidopsis thaliana 360000.0 4 PMID:18028193;PMID:18262499;PMID:21569035;PMID:3922244 -3.4.11.1 * aspergillus oryzae 130000.0 5 PMID:20803144 -3.4.11.1 * babesia gibsoni 85000.0 2 PMID:19549347 -3.4.11.1 * bacillus cereus 54000.0 1 PMID:37958921 -3.4.11.1 * bacillus sp. (in: firmicutes) 58000.0 2 * -3.4.11.1 * bos taurus 360000.0 6 PMID:14583094;PMID:17107951;PMID:18028193;PMID:21861921;PMID:7417261 -3.4.11.1 * brassica sp. 360000.0 1 * -3.4.11.1 * brevibacterium linens 95000.0 2 * -3.4.11.1 * burkholderia pseudomallei 52700.0 1 PMID:23682954 -3.4.11.1 * cannabis sativa 78000.0 1 PMID:10879480 -3.4.11.1 * clonorchis sinensis 59800.0 1 PMID:22729885 -3.4.11.1 * cryptosporidium parvum 58000.0 1 PMID:21414242 -3.4.11.1 * desulfurococcus amylolyticus 43200.0 2 PMID:22419090 -3.4.11.1 * echinococcus multilocularis 57400.0 2 PMID:34303691 -3.4.11.1 * eisenia fetida 100000.0 2 PMID:10462513 -3.4.11.1 * encephalitozoon cuniculi 74000.0 1 PMID:12435118 -3.4.11.1 * encephalitozoon hellem 72000.0 1 PMID:12435118 -3.4.11.1 * escherichia coli 53500.0 1 PMID:10672029 -3.4.11.1 * fasciola gigantica 56500.0 2 PMID:22543100;PMID:23917327 -3.4.11.1 * fasciola hepatica 59080.0 2 PMID:21939713;PMID:37329826 -3.4.11.1 * gallus gallus 360000.0 1 PMID:2298275 -3.4.11.1 * geobacillus kaustophilus 54000.0 1 PMID:18848841 -3.4.11.1 * haemaphysalis longicornis 56420.0 1 PMID:16814790 -3.4.11.1 * helicobacter pylori 260000.0 2 PMID:23989151 -3.4.11.1 * homo sapiens 360000.0 10 PMID:11056387;PMID:16585582;PMID:1680222;PMID:18996364;PMID:1931152;PMID:3733731 -3.4.11.1 * hordeum vulgare 360000.0 2 * -3.4.11.1 * lactobacillus acidophilus 156000.0 2 PMID:6432050 -3.4.11.1 * lactococcus lactis subsp. lactis 54300.0 1 * -3.4.11.1 * leishmania amazonensis 360000.0 2 * -3.4.11.1 * leishmania donovani 62337.0 1 * -3.4.11.1 * leishmania major 62569.0 2 PMID:33775769 -3.4.11.1 * lingulaulax polyedra 100000.0 2 PMID:10462513 -3.4.11.1 * mesomycoplasma hyopneumoniae 500000.0 2 PMID:25589579 -3.4.11.1 * morimus funereus 400000.0 3 PMID:12568801;PMID:18155948;PMID:8229672 -3.4.11.1 * pagrus major 96000.0 1 PMID:18800800 -3.4.11.1 * paragonimus westermani 58000.0 1 PMID:18394951 -3.4.11.1 * pediculus humanus corporis 69000.0 1 * -3.4.11.1 * phaseolus vulgaris 360000.0 6 * -3.4.11.1 * plasmodium falciparum 320000.0 4 PMID:14583094;PMID:16286469;PMID:17107951;PMID:18028193;PMID:21861921 -3.4.11.1 * plasmodium vivax 67800.0 1 PMID:19931315 -3.4.11.1 * pseudomonas aeruginosa 400000.0 3 PMID:11533066;PMID:18155948;PMID:8229672 -3.4.11.1 * pyrococcus horikoshii 475000.0 1 PMID:15736957 -3.4.11.1 * salmonella enterica 270000.0 1 PMID:10852868 -3.4.11.1 * schistosoma mansoni 360000.0 3 PMID:15111092;PMID:2298275 -3.4.11.1 * schizosaccharomyces pombe 320000.0 2 PMID:14583094;PMID:17107951;PMID:18028193;PMID:18262499;PMID:21861921;PMID:3922244 -3.4.11.1 * setaria cervi 321000.0 2 PMID:18028193;PMID:18262499;PMID:3922244 -3.4.11.1 * solanum lycopersicum 360000.0 4 PMID:10672029;PMID:11895433 -3.4.11.1 * solanum tuberosum 360000.0 4 * -3.4.11.1 * spinacia oleracea 360000.0 1 * -3.4.11.1 * streptomyces canus 55000.0 1 PMID:33259841 -3.4.11.1 * streptomyces hygroscopicus 67000.0 2 PMID:16233308 -3.4.11.1 * streptomyces rimosus 27500.0 1 * -3.4.11.1 * sus scrofa 360000.0 4 PMID:10672029;PMID:10862905;PMID:18028193;PMID:18262499;PMID:3922244;PMID:7284403 -3.4.11.1 * thermomyces lanuginosus 45000.0 1 PMID:31759085 -3.4.11.1 * thermotoga maritima 40000.0 1 * -3.4.11.1 * toxoplasma gondii 500000.0 3 PMID:19931316 -3.4.11.1 * trypanosoma cruzi 330000.0 3 PMID:14583094;PMID:17107951;PMID:18028193;PMID:21861921 -3.4.11.1 * vibrio cholerae 54620.0 1 PMID:19149671 -3.4.11.1 * vibrio proteolyticus 31880.0 2 PMID:1012016 -3.4.11.10 * aeromonas caviae 31000.0 2 * -3.4.11.10 * bacillus subtilis 46425.0 1 PMID:15583392 -3.4.11.10 * borreliella burgdorferi 300000.0 2 PMID:15784569 -3.4.11.10 * brevibacterium linens 220000.0 5 PMID:14743975 -3.4.11.10 * escherichia coli 340000.0 5 PMID:14743975;PMID:20350528;PMID:4920230 -3.4.11.10 * fasciola gigantica 56500.0 2 PMID:22543100;PMID:23917327 -3.4.11.10 * fasciola hepatica 67000.0 1 PMID:18178266 -3.4.11.10 * geobacillus stearothermophilus 61000.0 3 PMID:18286359;PMID:20373125 -3.4.11.10 * geobacillus thermoleovorans 42977.0 1 PMID:15937698 -3.4.11.10 * helicobacter pylori 340000.0 3 PMID:15942008;PMID:23989151 -3.4.11.10 * metamycoplasma salivarium 50000.0 2 PMID:14743975 -3.4.11.10 * mycobacterium tuberculosis 323000.0 1 PMID:28396657 -3.4.11.10 * mycoplasmopsis gallinarum 51000.0 1 PMID:15018100 -3.4.11.10 * pseudomonas aeruginosa 66000.0 3 PMID:19213733 -3.4.11.10 * pseudomonas putida 400000.0 3 PMID:14743975;PMID:20359484 -3.4.11.10 * treponema denticola 52000.0 1 PMID:18482986 -3.4.11.10 * vibrio proteolyticus 43000.0 7 PMID:1012016;PMID:15358350;PMID:1550363;PMID:19233285;PMID:4961737;PMID:5102149 -3.4.11.10 * xanthomonas oryzae pv. oryzae kacc 10331 51000.0 1 PMID:19724142 -3.4.11.13 * hathewaya histolytica 340000.0 2 PMID:13266;PMID:4318;PMID:4631895 -3.4.11.14 * acinetobacter calcoaceticus 80000.0 1 PMID:8229672 -3.4.11.14 * danio rerio 98000.0 1 PMID:21276865 -3.4.11.14 * homo sapiens 242000.0 5 PMID:1012014;PMID:4841062;PMID:698181 -3.4.11.14 * pseudomonas aeruginosa 80000.0 1 PMID:8229672 -3.4.11.14 * rattus norvegicus 110000.0 3 PMID:17476590;PMID:9687021 -3.4.11.15 * lactobacillus helveticus 129000.0 1 * -3.4.11.15 * legionella pneumophila 35000.0 1 PMID:18083880 -3.4.11.15 * pyrococcus furiosus 160000.0 3 PMID:15743956 -3.4.11.15 * pyrococcus horikoshii 500000.0 2 PMID:19291145 -3.4.11.15 * saccharomyces cerevisiae 75000.0 5 PMID:6758786;PMID:8175799;PMID:8175800 -3.4.11.15 * yarrowia lipolytica 97000.0 1 PMID:17227470 -3.4.11.16 * sus scrofa 130000.0 1 PMID:4062876 -3.4.11.17 * cutaneotrichosporon cutaneum 270000.0 2 * -3.4.11.18 * bacillus subtilis 27409.0 2 PMID:16207374 -3.4.11.18 * encephalitozoon cuniculi 40000.0 1 PMID:16004378 -3.4.11.18 * escherichia coli 41000.0 7 PMID:10460163;PMID:15901689;PMID:18952013;PMID:19019076;PMID:3027045 -3.4.11.18 * geobacillus stearothermophilus 81300.0 2 PMID:12297034 -3.4.11.18 * homo sapiens 54700.0 6 PMID:11524009;PMID:15196033;PMID:16568094;PMID:7644482 -3.4.11.18 * ixodes persulcatus 41000.0 1 PMID:33002807 -3.4.11.18 * leishmania donovani 453200.0 1 PMID:31759728 -3.4.11.18 * mycobacterium tuberculosis 39100.0 8 PMID:19688379;PMID:20038112;PMID:21729287;PMID:22466806;PMID:38138972 -3.4.11.18 * mycolicibacterium smegmatis 37000.0 2 PMID:18594775 -3.4.11.18 * plasmodium falciparum 90000.0 2 PMID:19246010 -3.4.11.18 * plasmodium vivax 53000.0 2 PMID:25595410 -3.4.11.18 * pyrococcus furiosus 33000.0 1 PMID:15628852 -3.4.11.18 * rattus norvegicus 74000.0 1 PMID:6795069 -3.4.11.18 * saccharomyces cerevisiae 44000.0 5 PMID:10075912;PMID:15210064;PMID:1569059;PMID:2246265 -3.4.11.18 * salmonella enterica subsp. enterica serovar typhimurium 35500.0 3 PMID:2651123 -3.4.11.18 * staphylococcus aureus 27000.0 1 PMID:12946343 -3.4.11.18 * sus scrofa 70000.0 2 PMID:1328207 -3.4.11.18 * xenopus laevis 65000.0 1 PMID:17415608 -3.4.11.19 * aspergillus oryzae 126300.0 3 PMID:22005737 -3.4.11.19 * bacillus subtilis 230000.0 4 PMID:11069674 -3.4.11.19 * brucella anthropi 122000.0 3 PMID:1540587;PMID:2760064 -3.4.11.2 * aedes aegypti 140000.0 3 PMID:19698787 -3.4.11.2 * anopheles gambiae 106000.0 1 PMID:18826260 -3.4.11.2 * bombyx mori 190000.0 6 PMID:12023048;PMID:16452310;PMID:8063017 -3.4.11.2 * bos taurus 58000.0 1 PMID:16717410 -3.4.11.2 * brucella melitensis 98000.0 3 PMID:12933870;PMID:17064279 -3.4.11.2 * capra hircus 140000.0 1 PMID:15905436 -3.4.11.2 * cavia porcellus 175000.0 1 PMID:16513561 -3.4.11.2 * cucumis sativus 200000.0 2 PMID:11826983 -3.4.11.2 * epiphyas postvittana 120000.0 1 * -3.4.11.2 * escherichia coli 99000.0 6 PMID:16380266;PMID:16820698;PMID:20350528;PMID:7041825 -3.4.11.2 * gallus gallus 150000.0 3 * -3.4.11.2 * heliothis virescens 170000.0 1 * -3.4.11.2 * homo sapiens 260000.0 15 PMID:16469741;PMID:18436850;PMID:18603472;PMID:18991640;PMID:2564389;PMID:2567164;PMID:2901990;PMID:6103715;PMID:6149934;PMID:8095183;PMID:9399582 -3.4.11.2 * hordeum vulgare 58000.0 1 PMID:31533309 -3.4.11.2 * lactococcus lactis 95000.0 1 * -3.4.11.2 * lymantria dispar 120000.0 1 PMID:6105876;PMID:8702277;PMID:9342226 -3.4.11.2 * manduca sexta 120000.0 2 PMID:15511230;PMID:6105876;PMID:8702277;PMID:9342226 -3.4.11.2 * mizuhopecten yessoensis 61000.0 2 * -3.4.11.2 * neisseria meningitidis 95000.0 1 PMID:17082929;PMID:17876832 -3.4.11.2 * novosphingobium capsulatum 66000.0 1 PMID:11359790 -3.4.11.2 * oryctolagus cuniculus 120000.0 1 PMID:6105876;PMID:8702277;PMID:9342226 -3.4.11.2 * plutella xylostella 130000.0 1 * -3.4.11.2 * rattus norvegicus 320000.0 12 PMID:240425;PMID:2564389;PMID:2567164;PMID:2901990;PMID:5938934;PMID:6122685;PMID:873921;PMID:931983 -3.4.11.2 * saccharomyces cerevisiae 97634.0 1 * -3.4.11.2 * spodoptera litura 46000.0 1 PMID:17609853 -3.4.11.2 * streptococcus salivarius 98000.0 1 PMID:7989254 -3.4.11.2 * streptomyces lividans 95000.0 1 PMID:17082929;PMID:17876832 -3.4.11.2 * streptomyces sp. 95000.0 2 PMID:17082929;PMID:17876832 -3.4.11.2 * sus scrofa 280000.0 6 PMID:19428736;PMID:20074871;PMID:357150;PMID:4750768;PMID:5938934;PMID:931983 -3.4.11.2 * tenebrio molitor 90000.0 1 * -3.4.11.2 * torpedo marmorata 180000.0 1 PMID:7849605 -3.4.11.2 * trichoplusia ni 110000.0 4 PMID:15857766 -3.4.11.2 * trypanosoma congolense 91000.0 2 PMID:24177338 -3.4.11.20 * gallus gallus 700000.0 4 PMID:8288037 -3.4.11.20 * plasmodium falciparum 343000.0 3 PMID:21659511;PMID:21844374;PMID:25123643 -3.4.11.20 * xanthomonas axonopodis 149000.0 4 PMID:17110128 -3.4.11.21 * aspergillus oryzae 57700.0 4 PMID:17928682 -3.4.11.21 * escherichia coli 35000.0 1 * -3.4.11.21 * homo sapiens 440000.0 3 * -3.4.11.21 * lactobacillus delbrueckii subsp. lactis 508000.0 1 PMID:27003449 -3.4.11.21 * lactococcus lactis ssp. lactis 470000.0 1 PMID:27003449 -3.4.11.21 * oryctolagus cuniculus 440000.0 2 PMID:9632644 -3.4.11.21 * plasmodium falciparum 560000.0 4 PMID:17720817 -3.4.11.21 * saccharomyces cerevisiae 680000.0 4 PMID:16367759;PMID:21343297 -3.4.11.21 * salmonella enterica subsp. enterica serovar typhimurium 26000.0 1 PMID:9928148 -3.4.11.21 * schizosaccharomyces pombe 200000.0 2 PMID:20044953 -3.4.11.21 * sus scrofa 400000.0 2 PMID:7011318 -3.4.11.21 * toxoplasma gondii 960000.0 2 PMID:27678060 -3.4.11.21 * trichinella spiralis 51760.0 1 PMID:34608116 -3.4.11.22 * aspergillus oryzae 56000.0 2 PMID:10899618 -3.4.11.22 * aspergillus sojae 41061.0 2 PMID:12031491 -3.4.11.22 * chara australis 120000.0 3 PMID:16665510 -3.4.11.22 * colwellia psychrerythraea 71000.0 1 PMID:15184127 -3.4.11.22 * cryptomeria japonica 43000.0 2 PMID:12033825 -3.4.11.22 * encephalitozoon cuniculi 74000.0 1 PMID:12435118 -3.4.11.22 * encephalitozoon hellem 72000.0 1 PMID:12435118 -3.4.11.22 * geobacillus stearothermophilus 400000.0 3 PMID:12783191 -3.4.11.22 * grifola frondosa 30000.0 2 PMID:11302180 -3.4.11.22 * helianthus annuus 60000.0 1 * -3.4.11.22 * hordeum vulgare 93000.0 2 PMID:10681066 -3.4.11.22 * morimus funereus 100000.0 1 PMID:12568801 -3.4.11.22 * mus musculus 105000.0 2 PMID:21531727;PMID:25577645 -3.4.11.22 * musca domestica 200000.0 1 * -3.4.11.22 * novosphingobium capsulatum 66000.0 1 PMID:11359790 -3.4.11.22 * parietaria judaica 98000.0 1 PMID:17030241 -3.4.11.22 * saccharomyces cerevisiae 640000.0 15 PMID:146355;PMID:17329814;PMID:19185714;PMID:5147;PMID:8482390 -3.4.11.23 * salmonella enterica subsp. enterica serovar typhimurium 270000.0 2 PMID:10852868 -3.4.11.24 * saccharomyces cerevisiae 290000.0 3 PMID:10649451 -3.4.11.24 * streptomyces griseus 34000.0 11 PMID:10771423;PMID:12821322;PMID:17608735;PMID:2503378;PMID:8450545;PMID:8665903;PMID:9874195 -3.4.11.25 * pseudomonas aeruginosa 42000.0 3 PMID:23728237 -3.4.11.25 * sphingosinicella microcystinivorans 155800.0 6 PMID:17064315 -3.4.11.25 * sphingosinicella xenopeptidilytica 150200.0 4 PMID:16109932;PMID:17064315 -3.4.11.26 * saccharomyces cerevisiae 106000.0 4 PMID:19837041;PMID:30582634 -3.4.11.27 * pyrococcus horikoshii 240000.0 2 PMID:11114201;PMID:25192005 -3.4.11.3 * homo sapiens 340000.0 16 PMID:10601849;PMID:2621691;PMID:38336;PMID:7925365;PMID:9013800 -3.4.11.3 * macaca fuscata fuscata 87000.0 1 PMID:12146 -3.4.11.3 * macaca radiata 106000.0 2 PMID:2754377 -3.4.11.3 * rattus norvegicus 140000.0 1 PMID:7993391 -3.4.11.3 * saccharomyces cerevisiae 52000.0 1 PMID:8482390 -3.4.11.3 * streptococcus thermophilus 300000.0 2 PMID:2621691;PMID:7925365 -3.4.11.3 * sus scrofa 105000.0 2 PMID:7873563 -3.4.11.4 * arabidopsis thaliana 153000.0 2 PMID:15908606 -3.4.11.4 * bacillus subtilis 51400.0 1 * -3.4.11.4 * bos taurus 230000.0 2 PMID:8177230 -3.4.11.4 * cavia porcellus 68000.0 1 PMID:3881261 -3.4.11.4 * escherichia coli 275000.0 2 PMID:20350528;PMID:356879 -3.4.11.4 * geobacillus stearothermophilus 108000.0 2 PMID:4455642 -3.4.11.4 * homo sapiens 100000.0 1 PMID:2276506;PMID:9406407 -3.4.11.4 * lactobacillus helveticus 150000.0 2 PMID:10653753 -3.4.11.4 * latilactobacillus sakei 55000.0 1 PMID:10554244 -3.4.11.4 * macaca fuscata 65000.0 1 PMID:6771256 -3.4.11.4 * mus musculus 140000.0 2 PMID:17582523;PMID:18056356 -3.4.11.4 * oryctolagus cuniculus 57000.0 2 PMID:109082 -3.4.11.4 * pediococcus pentosaceus 100000.0 2 PMID:2276506;PMID:9406407 -3.4.11.4 * porphyromonas gingivalis 154000.0 4 PMID:16914159;PMID:18042490 -3.4.11.4 * sus scrofa 137200.0 3 PMID:4735138 -3.4.11.5 * acinetobacter calcoaceticus 65000.0 1 PMID:8229672 -3.4.11.5 * aeromonas sobria 45000.0 1 * -3.4.11.5 * aneurinibacillus sp. 35000.0 1 PMID:15012820 -3.4.11.5 * aspergillus niger 316000.0 2 PMID:15654623 -3.4.11.5 * aspergillus oryzae 313000.0 4 PMID:20028436;PMID:24879594 -3.4.11.5 * brassica oleracea 204000.0 3 PMID:18386498 -3.4.11.5 * cutibacterium acnes 120000.0 1 PMID:4082822 -3.4.11.5 * debaryomyces hansenii 370000.0 2 PMID:12513999 -3.4.11.5 * elizabethkingia meningoseptica 35000.0 2 PMID:8951032 -3.4.11.5 * glutamicibacter nicotianae 53000.0 1 PMID:10483739 -3.4.11.5 * grifola frondosa 58000.0 3 PMID:15215614 -3.4.11.5 * hafnia alvei 180000.0 3 PMID:8830041 -3.4.11.5 * heyndrickxia coagulans 35000.0 1 * -3.4.11.5 * homo sapiens 550000.0 2 PMID:4803482 -3.4.11.5 * kitasatospora aureofaciens 250000.0 3 PMID:17916451 -3.4.11.5 * lactiplantibacillus plantarum 37900.0 1 PMID:29274418 -3.4.11.5 * lactobacillus delbrueckii 100000.0 3 PMID:8012576 -3.4.11.5 * lactococcus lactis 43000.0 1 * -3.4.11.5 * lathyrus oleraceus 44700.0 1 PMID:34697737 -3.4.11.5 * lyophyllum cinerascens 150000.0 2 * -3.4.11.5 * neisseria gonorrhoeae 35000.0 1 * -3.4.11.5 * penicillium camemberti 270000.0 3 * -3.4.11.5 * priestia megaterium 60000.0 2 PMID:6404902 -3.4.11.5 * prunus armeniaca 220000.0 2 PMID:7130149 -3.4.11.5 * pseudomonas aeruginosa 65000.0 1 PMID:8229672 -3.4.11.5 * rasamsonia emersonii 50600.0 2 PMID:19556294 -3.4.11.5 * secale cereale 55400.0 2 * -3.4.11.5 * serratia marcescens 35000.0 1 * -3.4.11.5 * streptomyces lavendulae 240000.0 2 PMID:24411439 -3.4.11.5 * streptomyces plicatus 120000.0 2 PMID:1590787 -3.4.11.5 * sus scrofa 550000.0 2 PMID:4803482 -3.4.11.5 * thermoplasma acidophilum 35000.0 1 * -3.4.11.5 * treponema denticola 100000.0 1 * -3.4.11.5 * triticum aestivum 400000.0 1 PMID:16663327 -3.4.11.5 * x triticosecale 43900.0 1 PMID:22330801 -3.4.11.5 * xanthomonas campestris 35000.0 2 PMID:17581124 -3.4.11.6 * aspergillus niger 100000.0 2 PMID:34290949 -3.4.11.6 * bos taurus 74000.0 3 PMID:17241125 -3.4.11.6 * capnocytophaga granulosa 270000.0 2 PMID:15720565 -3.4.11.6 * capra aegagrus 97400.0 3 * -3.4.11.6 * colwellia psychrerythraea 71000.0 1 PMID:15184127 -3.4.11.6 * homo sapiens 220000.0 8 PMID:1823861;PMID:2893791;PMID:3167075;PMID:7103502;PMID:7672445;PMID:8143849;PMID:8344358;PMID:8940051 -3.4.11.6 * latilactobacillus sakei 180000.0 2 PMID:11916721 -3.4.11.6 * mycosarcoma maydis 110000.0 2 PMID:15135529 -3.4.11.6 * pediococcus acidilactici 101360.0 2 * -3.4.11.6 * pseudoxanthomonas mexicana 73000.0 1 PMID:24637761 -3.4.11.6 * rattus norvegicus 95500.0 11 PMID:16475002;PMID:16981702;PMID:17241125;PMID:17974014;PMID:18571504;PMID:3167075;PMID:5957133;PMID:7672445;PMID:8344358;PMID:8940051 -3.4.11.6 * streptococcus gordonii 70000.0 2 PMID:11796618 -3.4.11.6 * streptococcus mitis 360000.0 2 PMID:6654852 -3.4.11.6 * sus scrofa 58000.0 1 PMID:7451402 -3.4.11.6 * toxoplasma gondii 110000.0 1 PMID:10910719 -3.4.11.6 * vittaforma corneae 78000.0 1 PMID:12435118 -3.4.11.7 * acinetobacter calcoaceticus 200000.0 1 PMID:8229672 -3.4.11.7 * aspergillus oryzae 37000.0 1 * -3.4.11.7 * cavia porcellus 400000.0 1 * -3.4.11.7 * gallus gallus 320000.0 2 PMID:2331880 -3.4.11.7 * gloydius blomhoffii 170000.0 1 PMID:18384831 -3.4.11.7 * glycine max 510000.0 2 PMID:20057138 -3.4.11.7 * homo sapiens 600000.0 7 PMID:12126112;PMID:17999179;PMID:4313532;PMID:6272866;PMID:6477935 -3.4.11.7 * lactobacillus delbrueckii subsp. lactis 508000.0 2 PMID:27003449;PMID:27815133 -3.4.11.7 * lactococcus cremoris 130000.0 2 PMID:16347306 -3.4.11.7 * lactococcus lactis 245000.0 2 * -3.4.11.7 * lactococcus lactis ssp. lactis 470000.0 1 PMID:27003449 -3.4.11.7 * mesomycoplasma hyopneumoniae 600000.0 4 PMID:23594879 -3.4.11.7 * mus musculus 400000.0 8 PMID:11829756;PMID:17999179;PMID:18175217;PMID:18194430;PMID:18598240;PMID:19228697 -3.4.11.7 * oryctolagus cuniculus 185000.0 2 PMID:7426665 -3.4.11.7 * plasmodium falciparum 560000.0 2 PMID:17720817 -3.4.11.7 * pseudomonas aeruginosa 200000.0 1 PMID:8229672 -3.4.11.7 * rattus norvegicus 400000.0 5 PMID:17999179;PMID:18175217;PMID:18194430;PMID:18387830 -3.4.11.7 * rhynchosciara americana 117000.0 1 * -3.4.11.7 * solanum lycopersicum 60000.0 1 PMID:17896114 -3.4.11.7 * staphylococcus chromogenes 430000.0 2 PMID:8425520 -3.4.11.7 * sus scrofa 400000.0 6 PMID:6105077;PMID:7011318;PMID:7448199 -3.4.11.7 * tetragenococcus halophilus 39130.0 1 PMID:36597589 -3.4.11.9 * aspergillus flavus 51600.0 1 PMID:38139441 -3.4.11.9 * aspergillus oryzae 129000.0 1 PMID:28698148 -3.4.11.9 * bos taurus 360000.0 3 PMID:1363864;PMID:1537867 -3.4.11.9 * caenorhabditis elegans 143268.0 3 PMID:11606206;PMID:25905034 -3.4.11.9 * cavia porcellus 217000.0 3 PMID:1540646 -3.4.11.9 * drosophila melanogaster 71000.0 1 PMID:11872174 -3.4.11.9 * escherichia coli 350000.0 6 PMID:2851590;PMID:4878817 -3.4.11.9 * homo sapiens 140000.0 4 PMID:11106490;PMID:18515364 -3.4.11.9 * lactococcus lactis 41600.0 2 PMID:9275257 -3.4.11.9 * lactococcus lactis subsp. lactis 40000.0 1 PMID:22853547 -3.4.11.9 * mycosarcoma maydis 125000.0 1 PMID:24402567 -3.4.11.9 * plasmodium falciparum 157000.0 3 PMID:19574214 -3.4.11.9 * rattus norvegicus 220000.0 5 PMID:1645659;PMID:18156635;PMID:7669781 -3.4.11.9 * saccharomyces cerevisiae 106000.0 1 PMID:30582634 -3.4.11.9 * solanum lycopersicum 105000.0 1 PMID:11423553 -3.4.11.9 * streptococcus thermophilus 175000.0 1 PMID:29329859 -3.4.11.9 * streptomyces lavendulae 240000.0 2 PMID:24411439 -3.4.11.9 * streptomyces murinus 220000.0 2 PMID:18156635 -3.4.11.9 * sus scrofa 280000.0 3 PMID:11106491;PMID:2139778 -3.4.11.9 * thermococcus onnurineus na1 39714.0 1 PMID:16517635 -3.4.13.12 * escherichia coli 95000.0 3 PMID:4567782 -3.4.13.12 * neurospora crassa 114000.0 1 PMID:4280316 -3.4.13.17 * loligo vulgaris 140000.0 3 PMID:6444201 -3.4.13.18 * bos taurus 100000.0 1 PMID:13264;PMID:2303;PMID:4074331;PMID:4596146 -3.4.13.18 * escherichia coli 100000.0 2 PMID:13264;PMID:2303;PMID:4074331;PMID:4596146 -3.4.13.18 * homo sapiens 210000.0 9 PMID:13264;PMID:16110352;PMID:17040910;PMID:17121880;PMID:2303;PMID:4074331;PMID:4214746;PMID:4596146;PMID:7817771 -3.4.13.18 * mus musculus 85000.0 2 PMID:13265;PMID:4596146;PMID:5542681 -3.4.13.18 * mycolicibacterium phlei 88000.0 2 PMID:4628031 -3.4.13.18 * platyrrhini 107000.0 2 PMID:4204951 -3.4.13.18 * porphyromonas gingivalis 54200.0 1 PMID:22001095 -3.4.13.18 * saccharomyces cerevisiae 130000.0 2 PMID:4611897 -3.4.13.18 * sus scrofa 70000.0 1 PMID:2378680 -3.4.13.19 * bifidobacterium longum 49000.0 1 PMID:17601807 -3.4.13.19 * homo sapiens 220000.0 14 PMID:17214548;PMID:2137335;PMID:23848;PMID:2768222;PMID:4074331;PMID:6334084 -3.4.13.19 * raphanus sativus 330000.0 4 PMID:18071263 -3.4.13.19 * rattus norvegicus 105000.0 5 PMID:17881305;PMID:6122685;PMID:6126478 -3.4.13.19 * sus scrofa 96000.0 8 PMID:2173907;PMID:22742779;PMID:2529850;PMID:2930455;PMID:3619022;PMID:4831361;PMID:5961612 -3.4.13.20 * brucella anthropi 30000.0 4 PMID:10377256 -3.4.13.20 * homo sapiens 167000.0 11 PMID:12473676;PMID:17601991;PMID:1903095;PMID:19915793;PMID:7116644 -3.4.13.20 * pseudomonas sp. 150000.0 3 PMID:15955066 -3.4.13.21 * escherichia coli 25000.0 1 PMID:19664550 -3.4.13.21 * salmonella enterica subsp. enterica serovar typhimurium 35000.0 3 PMID:6086568;PMID:8282693 -3.4.13.22 * enterococcus faecium 24200.0 3 PMID:15265748;PMID:16789876;PMID:7873524 -3.4.13.22 * streptomyces coelicolor 22700.0 1 PMID:11881895 -3.4.13.23 * saccharomyces cerevisiae 220000.0 1 PMID:8463237 -3.4.13.5 * anguilla japonica 52661.0 1 PMID:22525515 -3.4.13.5 * katsuwonus pelamis 120000.0 2 PMID:16302965;PMID:6067033 -3.4.13.5 * oncorhynchus mykiss 120000.0 2 * -3.4.13.5 * oreochromis niloticus 450000.0 3 PMID:16302965;PMID:30797810 -3.4.13.9 * aspergillus phoenicis 110000.0 2 * -3.4.13.9 * bos taurus 116000.0 1 PMID:2713125;PMID:4858820;PMID:6671971 -3.4.13.9 * cavia porcellus 132000.0 3 PMID:6853481 -3.4.13.9 * homo sapiens 210000.0 28 PMID:10567372;PMID:10867015;PMID:11067927;PMID:11173530;PMID:15169634;PMID:15902422;PMID:16122899;PMID:17040910;PMID:17081196;PMID:18340504;PMID:18443378;PMID:2317925;PMID:2713125;PMID:2925654;PMID:33045291;PMID:4858820;PMID:6671971;PMID:7817771;PMID:8174756 -3.4.13.9 * lacticaseibacillus casei 41000.0 1 PMID:8979358 -3.4.13.9 * lactobacillus delbrueckii 70000.0 2 PMID:10075426 -3.4.13.9 * lactobacillus gasseri 173000.0 1 * -3.4.13.9 * lactococcus cremoris 43000.0 1 * -3.4.13.9 * lactococcus lactis 80000.0 3 PMID:18070105 -3.4.13.9 * microbacterium esteraromaticum 440000.0 2 PMID:8782407 -3.4.13.9 * pyrococcus furiosus 100000.0 4 PMID:16243319;PMID:19426854;PMID:8541647;PMID:9733678 -3.4.13.9 * pyrococcus horikoshii 40000.0 2 PMID:19784642 -3.4.13.9 * stenotrophomonas maltophilia 100000.0 2 PMID:8541647;PMID:9733678 -3.4.13.9 * sus scrofa 116000.0 3 PMID:18443378;PMID:18455892;PMID:2713125;PMID:4858820;PMID:6671971 -3.4.13.9 * xanthomonas campestris pv. campestris 70000.0 1 PMID:25195907 -3.4.14.1 * bos taurus 210000.0 2 PMID:5961281 -3.4.14.1 * capra hircus 180000.0 2 PMID:8443565 -3.4.14.1 * homo sapiens 210000.0 5 PMID:1586157;PMID:1674238;PMID:8811434 -3.4.14.1 * penaeus japonicus 51000.0 1 PMID:19707514 -3.4.14.1 * penaeus monodon 50000.0 1 PMID:18468929 -3.4.14.1 * rattus norvegicus 150000.0 1 PMID:4215810 -3.4.14.1 * vigna radiata 38000.0 1 * -3.4.14.10 * drosophila melanogaster 150000.0 1 PMID:9668104 -3.4.14.10 * homo sapiens 1000000.0 5 PMID:10775413;PMID:17582523;PMID:18286570;PMID:3481262;PMID:3511062;PMID:3551927;PMID:6352701;PMID:8396212 -3.4.14.10 * mus musculus 145000.0 1 PMID:18822395 -3.4.14.10 * porphyromonas gingivalis 80000.0 2 PMID:19076991 -3.4.14.10 * rattus norvegicus 1000000.0 1 PMID:6352701;PMID:8396212 -3.4.14.11 * aspergillus oryzae 280000.0 2 * -3.4.14.11 * lacticaseibacillus casei 79000.0 1 PMID:7765768 -3.4.14.11 * lactobacillus delbrueckii 270000.0 5 PMID:7765315 -3.4.14.11 * lactobacillus gasseri 173000.0 1 * -3.4.14.11 * lactobacillus helveticus 180000.0 8 PMID:16348113;PMID:23894590;PMID:8574400 -3.4.14.11 * lactococcus lactis 190000.0 7 PMID:23894590;PMID:7710078 -3.4.14.11 * latilactobacillus sakei 170000.0 2 PMID:11282638 -3.4.14.11 * mycosarcoma maydis 125000.0 1 PMID:24402567 -3.4.14.11 * streptococcus thermophilus 170000.0 3 PMID:29329859;PMID:9519481 -3.4.14.12 * porphyromonas gingivalis 160000.0 9 PMID:16511231;PMID:16914159;PMID:18042490 -3.4.14.12 * prevotella nigrescens 56000.0 1 PMID:12620636 -3.4.14.12 * streptomyces mobaraensis 50000.0 1 PMID:15598885 -3.4.14.2 * bos taurus 200000.0 5 PMID:17328877;PMID:18774942;PMID:4969969;PMID:6342678 -3.4.14.2 * cavia porcellus 135000.0 1 * -3.4.14.2 * homo sapiens 120000.0 10 PMID:15487984;PMID:17055271;PMID:17328877;PMID:17352682;PMID:3597628 -3.4.14.2 * odoribacter splanchnicus 160000.0 2 PMID:9236738 -3.4.14.2 * rattus norvegicus 130000.0 8 PMID:11173530;PMID:15487984;PMID:17328877;PMID:2564425;PMID:4969969;PMID:6342678 -3.4.14.2 * streptomyces sp. 37000.0 1 PMID:7765287 -3.4.14.2 * sus scrofa 200000.0 10 PMID:17328877;PMID:2022295;PMID:3722177;PMID:8645718 -3.4.14.4 * arabidopsis thaliana 88000.0 1 PMID:27467751 -3.4.14.4 * blaberus craniifer 89000.0 4 PMID:19135055 -3.4.14.4 * capra hircus 69000.0 1 PMID:17182254 -3.4.14.4 * cavia porcellus 86000.0 1 PMID:2906822;PMID:3297170;PMID:3348886;PMID:3791505;PMID:6749851;PMID:7931295 -3.4.14.4 * corallococcus sp. egb 117700.0 1 PMID:36614072 -3.4.14.4 * dictyostelium discoideum 158000.0 1 * -3.4.14.4 * drosophila melanogaster 89000.0 2 PMID:16478478 -3.4.14.4 * homo sapiens 93000.0 7 PMID:11209758;PMID:17338643;PMID:18163885;PMID:19375145;PMID:2906822;PMID:3297170;PMID:3348886;PMID:3791505;PMID:6749851;PMID:7931295;PMID:9425109 -3.4.14.4 * pediococcus acidilactici 108000.0 1 PMID:30039431 -3.4.14.4 * physcomitrium patens 88000.0 1 PMID:27467751 -3.4.14.4 * rattus norvegicus 86000.0 1 PMID:2906822;PMID:3297170;PMID:3348886;PMID:3791505;PMID:6749851;PMID:7931295 -3.4.14.4 * saccharomyces cerevisiae 82000.0 1 PMID:19825391 -3.4.14.4 * sus scrofa 66000.0 2 PMID:2022295 -3.4.14.4 * vigna radiata 60000.0 3 * -3.4.14.5 * bos taurus 345000.0 3 PMID:1361338;PMID:361404;PMID:6338934;PMID:6749833 -3.4.14.5 * cavia porcellus 360000.0 2 PMID:2863262;PMID:6350036 -3.4.14.5 * gloydius brevicauda 116000.0 2 PMID:16828569 -3.4.14.5 * homo sapiens 400000.0 30 PMID:10951221;PMID:12483204;PMID:12675229;PMID:12832764;PMID:1354217;PMID:1358482;PMID:14691230;PMID:18600568;PMID:19267232;PMID:19268648;PMID:19545486;PMID:1971178;PMID:23671024;PMID:2859040;PMID:2860011;PMID:486089;PMID:6360158;PMID:6751824;PMID:6991515;PMID:8951616;PMID:962853;PMID:9685737 -3.4.14.5 * hordeum vulgare 105000.0 2 PMID:10677435 -3.4.14.5 * lactobacillus helveticus 93000.0 3 PMID:16348113 -3.4.14.5 * lactococcus lactis 190000.0 5 PMID:2461166;PMID:8592708 -3.4.14.5 * mus musculus 100000.0 2 PMID:2901831 -3.4.14.5 * mycosarcoma maydis 125000.0 1 PMID:24402567 -3.4.14.5 * porphyromonas gingivalis 140000.0 2 PMID:10639438 -3.4.14.5 * rattus norvegicus 260000.0 14 PMID:10931192;PMID:1354217;PMID:1361338;PMID:19545486;PMID:23938379;PMID:2461166;PMID:2563382;PMID:2859040;PMID:2885032;PMID:361404;PMID:6338934;PMID:6749833;PMID:7845210 -3.4.14.5 * stenotrophomonas maltophilia 165000.0 2 PMID:9010758 -3.4.14.5 * streptococcus anginosus 84000.0 1 PMID:16055397 -3.4.14.5 * streptococcus mitis 120000.0 2 PMID:7027961 -3.4.14.5 * streptococcus salivarius 109000.0 2 PMID:1684633 -3.4.14.5 * streptococcus suis 105000.0 2 PMID:19484301 -3.4.14.5 * streptococcus thermophilus 160000.0 2 PMID:9519481 -3.4.14.5 * sus scrofa 360000.0 14 PMID:1354217;PMID:1361338;PMID:19545486;PMID:2859040;PMID:2860011;PMID:2863262;PMID:361404;PMID:486089;PMID:6338934;PMID:6350036;PMID:667115;PMID:6749833;PMID:6783094;PMID:7150658;PMID:7896751;PMID:962853 -3.4.14.9 * aspergillus fumigatus 43000.0 2 PMID:16517617 -3.4.14.9 * aspergillus oryzae 89000.0 1 PMID:22878738 -3.4.14.9 * bos taurus 57000.0 1 PMID:748018 -3.4.14.9 * dictyostelium discoideum 217000.0 2 PMID:10410254 -3.4.14.9 * homo sapiens 700000.0 12 PMID:16091586;PMID:16839750;PMID:16895480;PMID:17174955;PMID:18411270;PMID:19038966;PMID:20340139;PMID:8215436 -3.4.14.9 * rattus norvegicus 290000.0 5 PMID:11843185;PMID:9659384 -3.4.14.9 * sus scrofa 250000.0 2 PMID:3882090 -3.4.15.1 * alitta virens 71000.0 2 PMID:10825662 -3.4.15.1 * bacillus pumilus 155000.0 2 PMID:1368555 -3.4.15.1 * bos taurus 800000.0 6 PMID:11403651;PMID:1966711;PMID:22770554;PMID:2851588;PMID:6256346;PMID:6287916 -3.4.15.1 * canis lupus familiaris 140000.0 2 PMID:183603;PMID:208622;PMID:6287916 -3.4.15.1 * equus caballus 113000.0 1 PMID:6287916 -3.4.15.1 * homo sapiens 330000.0 25 PMID:1848554;PMID:19071;PMID:1966711;PMID:202323;PMID:207335;PMID:2558109;PMID:2823638;PMID:2849459;PMID:2999099;PMID:3017438;PMID:3026491;PMID:35818993;PMID:6264817;PMID:6279576;PMID:6281622;PMID:6287916;PMID:8968386 -3.4.15.1 * mammalia 180000.0 2 PMID:7674927 -3.4.15.1 * oryctolagus cuniculus 300000.0 12 PMID:169257;PMID:183603;PMID:6287916;PMID:6305731;PMID:6754723 -3.4.15.1 * pseudomonas sp. 74000.0 2 PMID:9178563 -3.4.15.1 * rattus norvegicus 270000.0 6 PMID:191087;PMID:2172462;PMID:2991265;PMID:6287916 -3.4.15.1 * struthio camelus 200000.0 1 * -3.4.15.1 * struthio camelus australis 200000.0 1 * -3.4.15.1 * sus scrofa 320000.0 9 PMID:1668273;PMID:2439065;PMID:4366382;PMID:6287916 -3.4.15.1 * ucides cordatus 72000.0 1 PMID:25544039 -3.4.15.4 * bos taurus 240000.0 1 PMID:6385859 -3.4.15.5 * escherichia coli 97000.0 3 PMID:13271;PMID:7674945 -3.4.15.5 * salmonella enterica subsp. enterica serovar typhimurium 77270.0 1 PMID:1537804 -3.4.15.6 * aquipseudomonas alcaligenes 45000.0 1 PMID:18978083 -3.4.15.6 * pseudomonas anguilliseptica 43000.0 1 PMID:11986309 -3.4.15.6 * synechocystis sp. 28000.0 2 PMID:10429200 -3.4.15.6 * synechocystis sp. pcc 6803 56400.0 2 PMID:19591842 -3.4.16.2 * homo sapiens 115000.0 10 PMID:18178555;PMID:18396440;PMID:18656443;PMID:28321;PMID:7341916;PMID:8344943 -3.4.16.2 * mus musculus 60000.0 2 PMID:17111204;PMID:19620781 -3.4.16.2 * penicillium janthinellum 51000.0 1 PMID:18211097;PMID:18264573 -3.4.16.2 * stenotrophomonas maltophilia 330000.0 2 PMID:7766028 -3.4.16.2 * sus scrofa 210000.0 1 PMID:4692653 -3.4.16.2 * tenebrio molitor 105000.0 2 PMID:23499933 -3.4.16.4 * enterococcus faecalis 43000.0 1 PMID:97082 -3.4.16.4 * enterococcus faecium 35000.0 1 PMID:1510448 -3.4.16.4 * escherichia coli 49600.0 7 PMID:16965759;PMID:18539032;PMID:20015336 -3.4.16.4 * geobacillus stearothermophilus 46500.0 1 PMID:4211099;PMID:438218 -3.4.16.4 * mycobacterium tuberculosis 37600.0 1 PMID:38256057 -3.4.16.4 * nonomuraea sp. 25000.0 3 PMID:22788848;PMID:23497129 -3.4.16.4 * streptomyces sp. 53000.0 3 PMID:1445284;PMID:3888533;PMID:4464852;PMID:7238522 -3.4.16.5 * citrus sp. 175000.0 3 PMID:13268;PMID:5140815 -3.4.16.5 * homo sapiens 100000.0 8 PMID:17145787;PMID:19666471;PMID:19679197;PMID:19954752;PMID:24599961 -3.4.16.5 * kluyveromyces marxianus 67000.0 1 PMID:14984772 -3.4.16.5 * monascus pilosus 125000.0 3 PMID:15592905 -3.4.16.5 * monascus purpureus 132000.0 3 PMID:14749965 -3.4.16.5 * mus musculus 55000.0 1 PMID:19187242 -3.4.16.5 * phaseolus vulgaris 150000.0 5 PMID:17041149;PMID:17516654;PMID:18290624 -3.4.16.5 * saccharomyces cerevisiae 70000.0 6 PMID:11388806;PMID:13269;PMID:17392273;PMID:19270410;PMID:6289903 -3.4.16.5 * todarodes pacificus 42000.0 2 * -3.4.16.6 * aspergillus oryzae 58820.0 1 PMID:22961905 -3.4.16.6 * homo sapiens 180000.0 2 PMID:25294878;PMID:32509382 -3.4.16.6 * kluyveromyces lactis 67000.0 2 PMID:18396409 -3.4.16.6 * saccharomyces cerevisiae 54219.0 1 PMID:8307029 -3.4.17.1 * anopheles culicifacies 48500.0 1 PMID:24910441 -3.4.17.1 * bos taurus 233000.0 9 PMID:17705554;PMID:5140186 -3.4.17.1 * helicoverpa armigera 54000.0 2 PMID:19523067 -3.4.17.1 * homo sapiens 130000.0 13 PMID:14760754;PMID:17244818;PMID:17391648;PMID:19643669;PMID:8806703;PMID:938622 -3.4.17.1 * mammalia 36000.0 1 PMID:11766880 -3.4.17.1 * mayetiola destructor 47890.0 6 PMID:16876709 -3.4.17.1 * mus musculus 42000.0 1 PMID:17923505 -3.4.17.1 * patella vulgata 40000.0 1 PMID:507843 -3.4.17.1 * penaeus setiferus 30000.0 1 PMID:4704475 -3.4.17.1 * rattus norvegicus 39300.0 3 PMID:7018567;PMID:7371832 -3.4.17.1 * squalus acanthias 35000.0 1 PMID:5529813 -3.4.17.1 * struthio camelus 34600.0 2 PMID:8013741 -3.4.17.1 * sus scrofa 38900.0 3 PMID:14086721;PMID:7274215 -3.4.17.1 * tenebrio molitor 34990.0 7 PMID:17651235 -3.4.17.1 * trypanosoma cruzi 132000.0 3 PMID:17007610 -3.4.17.10 * aplysia californica 70000.0 1 PMID:9187366 -3.4.17.10 * bos taurus 50000.0 1 PMID:6411723;PMID:6808517 -3.4.17.10 * gallus gallus 53000.0 2 PMID:19603184 -3.4.17.10 * homo sapiens 54000.0 1 PMID:2549070 -3.4.17.10 * manduca sexta 57000.0 1 PMID:8000075 -3.4.17.10 * rattus norvegicus 55000.0 3 PMID:17543468;PMID:2822027 -3.4.17.11 * cohnella sp. a01 41600.0 1 PMID:36493965 -3.4.17.11 * flavobacterium sp. 53000.0 1 PMID:26657 -3.4.17.11 * pseudomonas sp. 83000.0 4 PMID:18594008;PMID:19911261;PMID:33832417;PMID:3838935 -3.4.17.11 * pseudomonas sp. rs-16 52000.0 1 PMID:29968955 -3.4.17.11 * pseudomonas sp. rs16 83000.0 1 PMID:33832417;PMID:3838935 -3.4.17.11 * stutzerimonas stutzeri 92000.0 2 PMID:5129727 -3.4.17.12 * canis lupus familiaris 54000.0 1 PMID:2394713 -3.4.17.12 * homo sapiens 73000.0 9 PMID:12457462;PMID:15066430;PMID:16470308;PMID:17208058;PMID:18957287;PMID:2775217;PMID:2914904;PMID:7674953 -3.4.17.12 * rattus norvegicus 65000.0 1 PMID:17207026 -3.4.17.13 * escherichia coli 39000.0 4 PMID:1729236;PMID:3521530 -3.4.17.13 * priestia megaterium 60000.0 2 PMID:109439 -3.4.17.13 * proteus vulgaris 32000.0 1 PMID:6754695 -3.4.17.13 * pseudomonas aeruginosa 56000.0 3 PMID:16162494 -3.4.17.14 * escherichia coli 50978.0 1 PMID:16402224 -3.4.17.14 * streptomyces albus 22080.0 1 PMID:6825689 -3.4.17.14 * streptomyces sp. 53300.0 2 PMID:4464852 -3.4.17.15 * homo sapiens 45000.0 2 PMID:8806703;PMID:9452479 -3.4.17.16 * penicillium janthinellum 51000.0 1 PMID:18211097;PMID:18264573 -3.4.17.16 * sus scrofa 240000.0 2 PMID:4038259;PMID:5500406 -3.4.17.17 * gallus gallus 90000.0 1 PMID:7452228 -3.4.17.18 * saccharothrix mutabilis subsp. capreolus 48480.0 2 * -3.4.17.18 * streptomyces griseus 48700.0 2 * -3.4.17.18 * thermoactinomyces vulgaris 38000.0 5 PMID:15721771;PMID:7674954 -3.4.17.19 * thermus aquaticus 58000.0 3 PMID:1369078;PMID:7765282 -3.4.17.19 * trypanosoma cruzi 128000.0 3 PMID:17007610 -3.4.17.2 * anopheles stephensi 48100.0 1 PMID:23569111 -3.4.17.2 * asterias amurensis 34000.0 1 PMID:12381380 -3.4.17.2 * bos taurus 57400.0 2 PMID:13823740;PMID:14001261 -3.4.17.2 * homo sapiens 65000.0 11 PMID:1009123;PMID:17398;PMID:19182372;PMID:19790060;PMID:807247 -3.4.17.2 * mus musculus 47000.0 1 PMID:19717511 -3.4.17.2 * patiria pectinifera 34000.0 1 PMID:12381380 -3.4.17.2 * penaeus setiferus 34200.0 2 PMID:4704475 -3.4.17.2 * salaria basilisca 34500.0 1 * -3.4.17.2 * scyliorhinus canicula 32000.0 1 * -3.4.17.2 * squalus acanthias 37000.0 1 * -3.4.17.2 * struthio camelus 35000.0 1 PMID:8697097 -3.4.17.2 * sus scrofa 70000.0 4 PMID:13823740;PMID:19717511 -3.4.17.20 * homo sapiens 435000.0 10 PMID:10777524;PMID:11786552;PMID:15313141;PMID:19182372;PMID:20466032;PMID:7782309;PMID:8195249;PMID:8916945;PMID:9442053 -3.4.17.21 * homo sapiens 100000.0 2 PMID:20047017;PMID:8570628 -3.4.17.21 * mus musculus 100000.0 1 PMID:19347959 -3.4.17.21 * rattus norvegicus 97000.0 4 PMID:19014361;PMID:2250024;PMID:9375657 -3.4.17.22 * anas platyrhynchos 170000.0 3 PMID:17206752;PMID:20181690;PMID:7797483 -3.4.17.22 * bos taurus 180000.0 3 PMID:7559630;PMID:8910535 -3.4.17.22 * drosophila melanogaster 150000.0 1 PMID:16556608 -3.4.17.22 * homo sapiens 180000.0 4 PMID:17641957;PMID:18535109;PMID:29131831;PMID:9064476 -3.4.17.22 * rattus norvegicus 180000.0 2 PMID:15918796 -3.4.17.23 * felis silvestris 42000.0 1 PMID:17658563 -3.4.17.23 * homo sapiens 92460.0 4 PMID:10924499;PMID:11815627;PMID:17906677;PMID:34964599 -3.4.17.23 * mus musculus 100000.0 4 PMID:17897633;PMID:24454948 -3.4.17.23 * rattus norvegicus 92000.0 2 PMID:17308000;PMID:17325232 -3.4.17.24 * mus musculus 90000.0 1 PMID:17244818 -3.4.17.3 * homo sapiens 320000.0 15 PMID:1164026;PMID:14687935;PMID:148463;PMID:2378615;PMID:2844769;PMID:6381017;PMID:6750606;PMID:7341915 -3.4.17.3 * mus musculus 52000.0 1 PMID:14687935 -3.4.17.3 * streptococcus mitis 122000.0 1 * -3.4.17.3 * sus scrofa 315000.0 5 PMID:955578 -3.4.17.6 * prescottella equi 230000.0 2 * -3.4.17.8 * bacillus subtilis 50000.0 1 PMID:4200864 -3.4.17.8 * streptomyces albus 22080.0 2 PMID:6704204;PMID:6825689 -3.4.18.1 * cyprinus carpio 28000.0 1 PMID:18294892 -3.4.18.1 * homo sapiens 58600.0 2 PMID:33227497 -3.4.18.1 * paralichthys olivaceus 33200.0 1 PMID:18674630 -3.4.18.1 * patiria pectinifera 32700.0 1 PMID:23274724 -3.4.18.1 * rattus norvegicus 52000.0 2 PMID:18700000;PMID:4346573;PMID:5029515 -3.4.19.1 * aeropyrum pernix 63030.0 1 PMID:21084296 -3.4.19.1 * aeropyrum pernix k1 126100.0 1 PMID:18325786 -3.4.19.1 * arabidopsis thaliana 350000.0 2 PMID:12966075 -3.4.19.1 * bos taurus 300000.0 2 PMID:10407158;PMID:12206506;PMID:24206103;PMID:7275011;PMID:8375399 -3.4.19.1 * cucumis sativus 350000.0 2 PMID:12966075 -3.4.19.1 * deinococcus radiodurans 265000.0 2 PMID:25195912 -3.4.19.1 * homo sapiens 812665.0 2 PMID:10395453;PMID:12206506;PMID:24206103;PMID:7275011;PMID:8375399 -3.4.19.1 * oryctolagus cuniculus 245000.0 1 PMID:2738058 -3.4.19.1 * pyrococcus horikoshii 73230.0 2 PMID:19303951;PMID:9651372 -3.4.19.1 * rattus norvegicus 423000.0 5 PMID:1137989;PMID:1547272;PMID:3305492 -3.4.19.1 * saccharolobus solfataricus 192000.0 7 PMID:20941418;PMID:22655081 -3.4.19.1 * sporosarcina psychrophila 130000.0 2 PMID:22558199 -3.4.19.1 * sus scrofa 300000.0 7 PMID:10407158;PMID:12206506;PMID:12760423;PMID:24206103;PMID:7275011;PMID:7906149;PMID:8375399;PMID:8576092 -3.4.19.1 * trematomus bernacchii 300000.0 4 PMID:12206506;PMID:24206103;PMID:7275011;PMID:8375399 -3.4.19.11 * lysinibacillus sphaericus 45000.0 1 PMID:8503890 -3.4.19.12 * bos taurus 30000.0 4 PMID:18064599;PMID:20164442;PMID:2532544;PMID:2539853;PMID:7999048 -3.4.19.12 * cricetulus griseus 38000.0 1 PMID:6280189 -3.4.19.12 * drosophila melanogaster 29000.0 1 PMID:18817875 -3.4.19.12 * gallus gallus 810000.0 10 PMID:7642526;PMID:9163518;PMID:9230110 -3.4.19.12 * homo sapiens 130000.0 5 PMID:16316632;PMID:16888648;PMID:20231490;PMID:7851534;PMID:9628861 -3.4.19.12 * ictalurus punctatus 37600.0 1 PMID:19266312 -3.4.19.12 * macaca fascicularis 28000.0 1 PMID:15664418 -3.4.19.12 * monopterus albus 26000.0 1 PMID:18076650 -3.4.19.12 * mus musculus 25100.0 2 PMID:19154771;PMID:19204867 -3.4.19.12 * oreochromis niloticus 27000.0 1 PMID:12210120 -3.4.19.12 * oryctolagus cuniculus 25000.0 1 PMID:18388347 -3.4.19.12 * plasmodium falciparum 100000.0 2 PMID:16925553 -3.4.19.12 * saccharomyces cerevisiae 29000.0 1 PMID:2555355 -3.4.19.12 * sus scrofa 24000.0 1 PMID:17671268 -3.4.19.13 * bacillus amyloliquefaciens 64509.0 1 PMID:28120195 -3.4.19.13 * escherichia coli 60000.0 3 PMID:12207027 -3.4.19.13 * helicobacter pylori 40000.0 2 PMID:17107958 -3.4.19.13 * pseudomonas fluorescens 57330.0 3 PMID:24232936 -3.4.19.13 * toona sinensis 90100.0 1 * -3.4.19.14 * mus musculus 75000.0 6 PMID:12163373;PMID:9139674 -3.4.19.15 * haloferax volcanii 26000.0 3 PMID:22970855 -3.4.19.2 * rhinella marina 48000.0 1 * -3.4.19.2 * sus scrofa 442000.0 1 PMID:1122284 -3.4.19.2 * toad 100000.0 2 PMID:6766314 -3.4.19.3 * bacillus amyloliquefaciens 72000.0 2 PMID:29893 -3.4.19.3 * bacillus subtilis 91000.0 3 PMID:1353026;PMID:1362573 -3.4.19.3 * bos taurus 214000.0 5 PMID:17119851;PMID:7824521;PMID:8811836;PMID:9597758 -3.4.19.3 * cavia porcellus 230000.0 2 PMID:6149121;PMID:7824521 -3.4.19.3 * deinococcus radiodurans 100000.0 1 PMID:30950401 -3.4.19.3 * enterobacter cloacae 74000.0 1 PMID:7824521 -3.4.19.3 * gallus gallus 86000.0 1 PMID:6131954 -3.4.19.3 * homo sapiens 24000.0 5 PMID:12651114;PMID:1675162;PMID:7824521 -3.4.19.3 * leishmania major 36000.0 2 PMID:17028008 -3.4.19.3 * oryctolagus cuniculus 230000.0 1 PMID:6149121;PMID:7824521 -3.4.19.3 * pseudomonas fluorescens 41000.0 3 PMID:7909543 -3.4.19.3 * pyrococcus furiosus 45643.0 4 PMID:9756623 -3.4.19.3 * rattus norvegicus 260000.0 4 PMID:29044;PMID:7824521 -3.4.19.3 * streptococcus pyogenes 85000.0 3 PMID:1353731;PMID:1357525 -3.4.19.3 * sus scrofa 260000.0 1 * -3.4.19.3 * thermococcus litoralis 108000.0 4 PMID:11057915;PMID:11210517 -3.4.19.5 * cavia porcellus 35000.0 3 PMID:24669941 -3.4.19.5 * escherichia coli 320000.0 2 PMID:12718528;PMID:18334484 -3.4.19.5 * homo sapiens 33020.0 5 PMID:19839645 -3.4.19.5 * lupinus luteus 75000.0 1 PMID:15265041 -3.4.19.6 * bos taurus 214000.0 1 PMID:9597758 -3.4.19.6 * oryctolagus cuniculus 230000.0 1 PMID:20504468;PMID:2566891;PMID:7925352 -3.4.19.6 * rattus norvegicus 230000.0 3 PMID:10785382;PMID:16611635 -3.4.19.6 * sus scrofa 260000.0 5 PMID:115687;PMID:11856362;PMID:20504468;PMID:2566891;PMID:7925352 -3.4.19.7 * rattus norvegicus 290000.0 2 PMID:7437450 -3.4.19.9 * bacillus phage phinit1 25000.0 1 PMID:17074794 -3.4.19.9 * bacillus sp. (in: firmicutes) 28000.0 1 PMID:17090946 -3.4.19.9 * bos taurus 108000.0 1 PMID:1150668 -3.4.19.9 * gallus gallus 80000.0 4 PMID:6892837;PMID:857896;PMID:870050 -3.4.19.9 * geobacillus thermodenitrificans 222000.0 6 PMID:20138205 -3.4.19.9 * homo sapiens 700000.0 12 PMID:1167162;PMID:16945597;PMID:20663;PMID:2867095;PMID:3759978;PMID:6892838;PMID:9614206 -3.4.19.9 * lathyrus oleraceus 55000.0 1 * -3.4.19.9 * micromonospora melanosporea 32000.0 1 PMID:1369992 -3.4.19.9 * myrothecium sp. 68000.0 1 * -3.4.19.9 * rattus norvegicus 80000.0 1 PMID:6547136 -3.4.19.9 * solanum lycopersicum 42000.0 6 PMID:18757550 -3.4.19.9 * sus scrofa 29000.0 1 PMID:2341911 -3.4.21.1 * bos taurus 25210.0 2 PMID:15654893;PMID:19186036 -3.4.21.1 * carassius auratus 28000.0 2 * -3.4.21.1 * diatraea saccharalis 27000.0 1 PMID:19194984 -3.4.21.1 * dosidicus gigas 31000.0 1 PMID:30263367 -3.4.21.1 * gadus morhua 26000.0 1 PMID:1764912 -3.4.21.1 * gallus gallus 26309.0 4 PMID:10480246;PMID:14321849;PMID:7633464 -3.4.21.1 * lucilia cuprina 26990.0 3 PMID:7704304 -3.4.21.1 * manduca sexta 24852.0 3 PMID:10480246;PMID:7633464 -3.4.21.1 * metarhizium anisopliae 18499.0 1 PMID:10692479 -3.4.21.1 * musca domestica 28000.0 1 PMID:22808532 -3.4.21.1 * panulirus interruptus 28000.0 2 PMID:25877639 -3.4.21.1 * penaeus californiensis 27000.0 2 PMID:25466006 -3.4.21.1 * pterygoplichthys disjunctivus 29000.0 1 PMID:22752357 -3.4.21.1 * rattus norvegicus 28000.0 1 PMID:18211899 -3.4.21.1 * sardinops caeruleus 25500.0 1 * -3.4.21.1 * sardinops sagax 26000.0 1 * -3.4.21.1 * sepia officinalis 28000.0 1 PMID:22808532 -3.4.21.1 * silurus glanis 39800.0 1 * -3.4.21.1 * solenopsis invicta 48000.0 2 PMID:10801356 -3.4.21.1 * struthio camelus 25000.0 1 PMID:18598777 -3.4.21.1 * thermotoga maritima 669000.0 1 PMID:9872409 -3.4.21.10 * amblysomus hottentotus 30469.0 1 PMID:18247330 -3.4.21.10 * bos taurus 43000.0 4 PMID:18247330;PMID:22729485;PMID:6802470 -3.4.21.10 * bradypus tridactylus 30066.0 1 PMID:18247330 -3.4.21.10 * canis lupus familiaris 40000.0 3 PMID:19754602 -3.4.21.10 * capra hircus 42000.0 2 PMID:2930460 -3.4.21.10 * cavia porcellus 45773.0 1 PMID:18247330 -3.4.21.10 * coturnix japonica 45000.0 1 PMID:21642383 -3.4.21.10 * cynocephalus volans 25649.0 1 PMID:18247330 -3.4.21.10 * diceros bicornis 30707.0 1 PMID:18247330 -3.4.21.10 * dugong dugon 30515.0 1 PMID:18247330 -3.4.21.10 * echinops telfairi 28794.0 1 PMID:18247330 -3.4.21.10 * elephantulus edwardii 30616.0 1 PMID:18247330 -3.4.21.10 * equus caballus 30679.0 1 PMID:18247330 -3.4.21.10 * erethizon dorsatum 30361.0 1 PMID:18247330 -3.4.21.10 * euphractus sexcinctus 26300.0 1 PMID:18247330 -3.4.21.10 * felis catus 30583.0 1 PMID:18247330 -3.4.21.10 * galegeeska rufescens 30809.0 1 PMID:18247330 -3.4.21.10 * gallus gallus 27000.0 1 PMID:1157926 -3.4.21.10 * homo sapiens 76000.0 3 PMID:18247330;PMID:4770802;PMID:6802470;PMID:6803760 -3.4.21.10 * hystrix brachyura 30413.0 1 PMID:18247330 -3.4.21.10 * lama glama 30276.0 1 PMID:18247330 -3.4.21.10 * loxodonta africana 30357.0 1 PMID:18247330 -3.4.21.10 * macroscelides proboscideus 30628.0 1 PMID:18247330 -3.4.21.10 * manis sp. dmr-2008 26896.0 1 PMID:18247330 -3.4.21.10 * meleagris gallopavo 360517.0 7 PMID:20561916;PMID:22268795;PMID:22704390 -3.4.21.10 * mus musculus 43016.0 1 PMID:18247330 -3.4.21.10 * ochotona princeps 30310.0 1 PMID:18247330 -3.4.21.10 * orycteropus afer 28582.0 1 PMID:18247330 -3.4.21.10 * oryctolagus cuniculus 68000.0 4 PMID:18247330;PMID:6424572 -3.4.21.10 * otospermophilus beecheyi 30604.0 1 PMID:18247330 -3.4.21.10 * ovis aries 38000.0 2 PMID:18247330;PMID:736895 -3.4.21.10 * procavia capensis 30233.0 1 PMID:18247330 -3.4.21.10 * puma concolor 30583.0 1 PMID:18247330 -3.4.21.10 * rattus fuscipes 30455.0 1 PMID:18247330 -3.4.21.10 * rattus norvegicus 48623.0 1 PMID:18247330 -3.4.21.10 * sorex cinereus 26746.0 1 PMID:18247330 -3.4.21.10 * sus scrofa 48000.0 4 PMID:4474129;PMID:4796249;PMID:6751982;PMID:7007201;PMID:7043204 -3.4.21.10 * sylvilagus floridanus 30534.0 1 PMID:18247330 -3.4.21.10 * tadarida brasiliensis 30138.0 1 PMID:18247330 -3.4.21.10 * talpa europaea 30202.0 1 PMID:18247330 -3.4.21.10 * tapirus pinchaque 30788.0 1 PMID:18247330 -3.4.21.10 * tragelaphus angasii 29689.0 1 PMID:18247330 -3.4.21.10 * trichechus manatus 30556.0 1 PMID:18247330 -3.4.21.10 * tupaia glis 30452.0 1 PMID:18247330 -3.4.21.10 * tursiops truncatus 28577.0 1 PMID:18247330 -3.4.21.100 * aspergillus fumigatus 479000.0 7 PMID:16517617 -3.4.21.100 * grifola frondosa 43000.0 2 PMID:15896366 -3.4.21.100 * pseudomonas sp. 42000.0 1 PMID:3548827 -3.4.21.101 * pseudomonas sp. 61070.0 3 PMID:3548827;PMID:7929375 -3.4.21.101 * xanthomonas sp. 84000.0 4 * -3.4.21.102 * arabidopsis thaliana 37900.0 1 PMID:9422718 -3.4.21.102 * brucella suis bv. 1 42500.0 1 PMID:16077124 -3.4.21.102 * escherichia coli 82000.0 7 PMID:10715137;PMID:1729701;PMID:8520476 -3.4.21.102 * oryza sativa indica group 139000.0 1 PMID:20097911 -3.4.21.102 * pseudomonas aeruginosa 43700.0 1 PMID:21204920 -3.4.21.102 * spinacia oleracea 50000.0 3 PMID:11099501;PMID:15726567;PMID:21707356 -3.4.21.102 * synechocystis sp. 35000.0 1 PMID:14670603 -3.4.21.102 * tetradesmus obliquus 35000.0 1 PMID:1544920 -3.4.21.103 * badhamia polycephala 68000.0 8 PMID:8540373 -3.4.21.103 * dictyostelium discoideum 58000.0 1 * -3.4.21.103 * physarum flavicomum 32000.0 1 * -3.4.21.104 * homo sapiens 80000.0 22 PMID:10946292;PMID:11290788;PMID:12421953;PMID:1460414;PMID:14604549;PMID:15728497;PMID:16189649;PMID:16227207;PMID:16395704;PMID:19234189;PMID:20002787;PMID:22071314;PMID:9087411 -3.4.21.104 * mus musculus 87000.0 2 PMID:15826378 -3.4.21.104 * rattus norvegicus 90000.0 3 PMID:16189649;PMID:19494295 -3.4.21.105 * bacillus spizizenii 204000.0 3 PMID:22921757 -3.4.21.105 * entamoeba histolytica 36000.0 1 PMID:18559479 -3.4.21.105 * escherichia coli 141500.0 3 PMID:22921757 -3.4.21.105 * haemophilus influenzae 135100.0 3 PMID:22921757 -3.4.21.105 * plasmodium berghei 69000.0 1 PMID:22911675 -3.4.21.105 * saccharomyces cerevisiae 38800.0 3 PMID:15979251;PMID:20045481 -3.4.21.106 * cricetulus griseus 51000.0 1 * -3.4.21.106 * homo sapiens 75000.0 14 PMID:15627507;PMID:17569629;PMID:1801756;PMID:1885621;PMID:19302215;PMID:20673210;PMID:7845200 -3.4.21.106 * mus musculus 31000.0 1 PMID:15324701 -3.4.21.106 * rattus norvegicus 62000.0 10 PMID:16651711;PMID:17569629;PMID:9003440 -3.4.21.107 * bacillus subtilis 37000.0 1 * -3.4.21.107 * chlamydia trachomatis 307000.0 2 PMID:17604025 -3.4.21.107 * escherichia coli 500000.0 18 PMID:10417648;PMID:12878036;PMID:19424634;PMID:2180903;PMID:2540154;PMID:6347072;PMID:7557477;PMID:8830688 -3.4.21.107 * escherichia coli k-12 553100.0 6 PMID:22245966 -3.4.21.107 * helicobacter pylori 50000.0 1 PMID:20814423 -3.4.21.107 * homo sapiens 120000.0 7 PMID:19424634;PMID:20068077;PMID:20671064;PMID:2540154;PMID:31036715;PMID:31197037;PMID:31470122 -3.4.21.107 * mus musculus 50000.0 2 PMID:15861393 -3.4.21.107 * pseudomonas syringae pv. syringae 110400.0 1 PMID:37976815 -3.4.21.107 * streptococcus pneumoniae 45000.0 1 PMID:15937159 -3.4.21.107 * thermotoga maritima 26000.0 1 PMID:11752803 -3.4.21.107 * xenopus laevis 50000.0 1 PMID:17681134 -3.4.21.108 * drosophila melanogaster 46000.0 6 PMID:18259196;PMID:19282869 -3.4.21.108 * homo sapiens 110000.0 22 PMID:10644717;PMID:10873535;PMID:11583623;PMID:11602612;PMID:11606597;PMID:14711507;PMID:16520551;PMID:16968707;PMID:18241672;PMID:18364387;PMID:18600068;PMID:18769594;PMID:18786092;PMID:19076428;PMID:19355862;PMID:20202124 -3.4.21.108 * mammalia 110000.0 3 PMID:11604410;PMID:11967569 -3.4.21.108 * mus musculus 77000.0 9 PMID:14711507;PMID:17939055;PMID:18288109;PMID:18772386;PMID:20064504;PMID:20467442 -3.4.21.108 * penaeus monodon 47620.0 3 PMID:24096090 -3.4.21.109 * homo sapiens 240000.0 53 PMID:10373424;PMID:10373425;PMID:10831593;PMID:10962009;PMID:11231297;PMID:11792696;PMID:14747469;PMID:15800053;PMID:15832373;PMID:16420484;PMID:16566926;PMID:16999819;PMID:17344310;PMID:17981575;PMID:18263585;PMID:18449907;PMID:18550704;PMID:18723439;PMID:18976966;PMID:19242518;PMID:19302215;PMID:19535514;PMID:19940125;PMID:20473895;PMID:20601429;PMID:20684597;PMID:21678412;PMID:23443662 -3.4.21.109 * mus musculus 90000.0 1 * -3.4.21.109 * rattus norvegicus 110000.0 25 PMID:15669920;PMID:19202271;PMID:19398443;PMID:19800422;PMID:19897900;PMID:20378965 -3.4.21.110 * streptococcus iniae 123300.0 1 PMID:18665241 -3.4.21.111 * thermus aquaticus 80000.0 13 PMID:10446366;PMID:11027666;PMID:11114254;PMID:18216068;PMID:18685213;PMID:3162211;PMID:8056296;PMID:8733236;PMID:9070839 -3.4.21.111 * thermus thermophilus 28000.0 1 PMID:10446366;PMID:8056296 -3.4.21.112 * homo sapiens 148000.0 6 PMID:10644685;PMID:16973377;PMID:17623657;PMID:23884247;PMID:9990022 -3.4.21.112 * rattus norvegicus 98000.0 2 PMID:18850104 -3.4.21.114 * equine arteritis virus 31000.0 2 PMID:8617757 -3.4.21.115 * blotched snakehead virus 28500.0 1 PMID:16582483;PMID:2219718 -3.4.21.115 * infectious pancreatic necrosis virus 28500.0 3 PMID:16582483;PMID:17553791;PMID:2219718 -3.4.21.115 * marine birnavirus 240000.0 1 PMID:17334948 -3.4.21.115 * tellina virus 1 24745.0 1 PMID:21288899 -3.4.21.116 * bacillus subtilis 50000.0 10 PMID:10931284;PMID:11418578;PMID:12940997;PMID:15292188;PMID:2106508 -3.4.21.117 * homo sapiens 25000.0 1 PMID:1685827;PMID:8393902 -3.4.21.117 * rattus norvegicus 19000.0 2 PMID:2194829 -3.4.21.118 * homo sapiens 35000.0 3 PMID:10485494;PMID:16337200;PMID:17761692 -3.4.21.118 * mus musculus 32000.0 5 PMID:7623137;PMID:9556608 -3.4.21.118 * rattus norvegicus 18000.0 2 PMID:2194829 -3.4.21.119 * homo sapiens 50000.0 2 PMID:12507963 -3.4.21.119 * mus musculus 54000.0 5 PMID:2180937;PMID:9232643 -3.4.21.12 * achromobacter lyticus 19910.0 1 PMID:9399581 -3.4.21.12 * myxobacter sp. 19870.0 1 PMID:5482494 -3.4.21.120 * bos taurus 97000.0 1 PMID:19925651 -3.4.21.120 * xenopus laevis 66000.0 1 PMID:1581303 -3.4.21.121 * aeromonas sobria 66640.0 2 PMID:11092244;PMID:16487335;PMID:18462393;PMID:19654332 -3.4.21.122 * homo sapiens 70000.0 2 PMID:11245484 -3.4.21.122 * mus musculus 53529.0 1 PMID:10683448 -3.4.21.123 * alicyclobacillus acidocaldarius 45000.0 1 * -3.4.21.123 * alicyclobacillus sendaiensis 57000.0 3 PMID:16704427 -3.4.21.123 * bacillus novosp. 64000.0 6 PMID:8416942 -3.4.21.123 * heyndrickxia coagulans 64000.0 4 * -3.4.21.19 * bacillus intermedius 29000.0 3 PMID:14640964;PMID:15187226;PMID:9119071;PMID:9360302 -3.4.21.19 * bacillus licheniformis 25000.0 1 PMID:1429718 -3.4.21.19 * lathyrus oleraceus 95000.0 1 * -3.4.21.19 * staphylococcus aureus 44000.0 7 PMID:18199287;PMID:18616923;PMID:25679492;PMID:35708833;PMID:4627743 -3.4.21.19 * staphylococcus epidermidis 28000.0 2 PMID:18783343;PMID:19090719 -3.4.21.19 * staphylococcus warneri 38000.0 3 PMID:18616923;PMID:19090719 -3.4.21.19 * streptomyces griseus 18263.0 1 PMID:8931145 -3.4.21.2 * conogethes punctiferalis 72100.0 1 PMID:18072546 -3.4.21.2 * sus scrofa 31800.0 2 PMID:1260039;PMID:14253410 -3.4.21.20 * bos taurus 28000.0 1 PMID:10415105;PMID:21383996 -3.4.21.20 * canis lupus familiaris 29400.0 3 PMID:11703184;PMID:1910580 -3.4.21.20 * homo sapiens 39000.0 6 PMID:18021746;PMID:19528350;PMID:19648270;PMID:24877096;PMID:3799965;PMID:7244;PMID:7341917 -3.4.21.20 * oryctolagus cuniculus 27000.0 1 PMID:7576231 -3.4.21.20 * ovis aries 28000.0 1 PMID:10415105;PMID:21383996 -3.4.21.20 * rattus norvegicus 28900.0 2 PMID:2222858 -3.4.21.21 * homo sapiens 55000.0 6 PMID:17073711;PMID:18642129;PMID:20213530;PMID:21236324 -3.4.21.22 * bos taurus 55000.0 6 PMID:1794990;PMID:4473201 -3.4.21.22 * homo sapiens 70000.0 10 PMID:15755260;PMID:15913649;PMID:19656280;PMID:20397061;PMID:21069460;PMID:23994528;PMID:681330 -3.4.21.25 * cucumis melo 86000.0 5 PMID:16603211;PMID:21173569;PMID:5423;PMID:7576259;PMID:7806492;PMID:8586630 -3.4.21.25 * cucumis trigonus 67000.0 1 PMID:16603211;PMID:7576259;PMID:8586630 -3.4.21.25 * ficus religiosa 80000.0 1 * -3.4.21.25 * glycine max 70000.0 1 PMID:17229757 -3.4.21.26 * aeromonas hydrophila 76000.0 1 PMID:7588785;PMID:8370677 -3.4.21.26 * agaricus bisporus 78000.0 2 PMID:1644866;PMID:2113924 -3.4.21.26 * ascidia sp. 66000.0 1 * -3.4.21.26 * aspergillus niger 63000.0 1 PMID:19757411 -3.4.21.26 * aspergillus oryzae 64800.0 3 PMID:24241934;PMID:25547787 -3.4.21.26 * bos taurus 76000.0 8 PMID:1569074;PMID:6351752;PMID:6361010;PMID:6768725;PMID:7028730;PMID:7835390 -3.4.21.26 * clupea pallasii 79000.0 1 * -3.4.21.26 * conocybe apala 80000.0 1 PMID:18571285;PMID:19389704 -3.4.21.26 * coprinopsis clastophylla 84000.0 1 PMID:22923115 -3.4.21.26 * daucus carota 75000.0 1 PMID:6361010 -3.4.21.26 * elizabethkingia meningoseptica 76780.0 4 PMID:1569074;PMID:6351752;PMID:6768725;PMID:7028730;PMID:7835390 -3.4.21.26 * eurygaster integriceps 97000.0 1 PMID:20568295 -3.4.21.26 * halocynthia roretzi 66000.0 1 PMID:6361007 -3.4.21.26 * homo sapiens 174000.0 16 PMID:17196652;PMID:18718510;PMID:19332125;PMID:19875179;PMID:22101193;PMID:22750443;PMID:2300;PMID:3480758;PMID:6370309;PMID:7588785;PMID:8089089;PMID:8370677 -3.4.21.26 * lyophyllum cinerascens 76000.0 1 * -3.4.21.26 * mus musculus 80000.0 4 PMID:1644866;PMID:17196652;PMID:6351752;PMID:6768725;PMID:7028730;PMID:7835390 -3.4.21.26 * myxococcus xanthus 76800.0 1 PMID:24752841 -3.4.21.26 * novosphingobium capsulatum 78433.0 3 PMID:9750174 -3.4.21.26 * oryctolagus cuniculus 68000.0 1 * -3.4.21.26 * ovis aries 115000.0 6 PMID:2300;PMID:6351752;PMID:6370309;PMID:6768725;PMID:7028730;PMID:7835390 -3.4.21.26 * pseudomonas sp. 76000.0 1 PMID:7588785;PMID:8370677 -3.4.21.26 * pyrococcus furiosus 110000.0 5 PMID:16714022;PMID:17160352;PMID:8148011;PMID:9171407 -3.4.21.26 * rattus norvegicus 80000.0 5 PMID:19332125;PMID:19875179;PMID:21160163;PMID:22101193 -3.4.21.26 * spinacia oleracea 45000.0 1 PMID:1563512 -3.4.21.26 * sus scrofa 95000.0 7 PMID:18571285;PMID:18657187;PMID:19389704 -3.4.21.26 * thermococcus onnurineus 72000.0 3 PMID:17434424 -3.4.21.26 * trichormus variabilis 70000.0 2 PMID:8148011;PMID:9171407 -3.4.21.26 * trypanosoma brucei brucei 77600.0 1 PMID:20188209 -3.4.21.26 * trypanosoma cruzi 80000.0 3 PMID:15581422;PMID:17034776 -3.4.21.26 * xanthomonas sp. 75000.0 1 * -3.4.21.27 * homo sapiens 362500.0 15 PMID:15545266;PMID:15829482;PMID:16042419;PMID:16204896;PMID:1645530;PMID:19178150;PMID:19630773;PMID:19630774;PMID:20456758;PMID:25092234;PMID:6604052 -3.4.21.27 * mus musculus 160000.0 2 PMID:19630773;PMID:19630774;PMID:20456758 -3.4.21.32 * carcinus maenas 23000.0 1 PMID:8896334 -3.4.21.32 * gadus morhua 24100.0 1 PMID:7749622 -3.4.21.32 * leptuca pugilator 25000.0 3 PMID:4633482;PMID:6337626 -3.4.21.32 * novoden modestrus 27000.0 1 PMID:12297025 -3.4.21.32 * paralithodes camtschaticus 30000.0 3 PMID:14731305;PMID:7953075 -3.4.21.34 * bos taurus 95000.0 2 PMID:1011999;PMID:4474835;PMID:6918767 -3.4.21.34 * homo sapiens 163000.0 23 PMID:1011999;PMID:11379773;PMID:11383556;PMID:12002409;PMID:12489800;PMID:16895484;PMID:18413232;PMID:23846131;PMID:4474835;PMID:6815193;PMID:6914195;PMID:9514601;PMID:97200 -3.4.21.34 * schistosoma mansoni 35000.0 1 * -3.4.21.35 * canis lupus familiaris 36000.0 6 PMID:1492090 -3.4.21.35 * cyprinus carpio 72000.0 3 PMID:16849838 -3.4.21.35 * homo sapiens 53000.0 12 PMID:10191281;PMID:10232657;PMID:1320938;PMID:16467084;PMID:3937523;PMID:6921144;PMID:8812865;PMID:9535704 -3.4.21.35 * rattus norvegicus 43000.0 13 PMID:10191281;PMID:10232657;PMID:1287650;PMID:1320938;PMID:20482314;PMID:2194829;PMID:22622459;PMID:3070295;PMID:3237072;PMID:6566577 -3.4.21.35 * salmo salar 39000.0 1 PMID:20970199 -3.4.21.35 * sus scrofa 35000.0 3 PMID:1011997 -3.4.21.36 * gadus morhua 28000.0 1 PMID:2085959 -3.4.21.36 * homo sapiens 30790.0 3 PMID:234742;PMID:824194 -3.4.21.36 * mus musculus 25900.0 1 PMID:19085241 -3.4.21.36 * ovis aries 25000.0 1 PMID:9787815 -3.4.21.36 * rattus norvegicus 29000.0 2 PMID:6555050;PMID:7647093 -3.4.21.36 * salmo salar 27000.0 1 PMID:9628006 -3.4.21.36 * sus scrofa 25900.0 2 PMID:17266656;PMID:4857661 -3.4.21.37 * bos taurus 29000.0 1 PMID:19136576;PMID:7722333 -3.4.21.37 * equus caballus 27000.0 1 PMID:19932512 -3.4.21.37 * homo sapiens 34970.0 7 PMID:16986121;PMID:18674571;PMID:19136576;PMID:24376583;PMID:3550808;PMID:7722333;PMID:810168 -3.4.21.37 * mus musculus 60000.0 1 PMID:19049643 -3.4.21.38 * bos taurus 74000.0 5 PMID:367103;PMID:901768 -3.4.21.38 * homo sapiens 80000.0 5 PMID:18793325;PMID:6918768 -3.4.21.38 * rattus norvegicus 30000.0 1 PMID:22216926 -3.4.21.39 * canis lupus familiaris 32000.0 1 PMID:20338912 -3.4.21.39 * cricetinae 10000.0 1 PMID:11342040 -3.4.21.39 * homo sapiens 33000.0 9 PMID:10082988;PMID:15163313;PMID:17342483;PMID:18022236;PMID:18845543;PMID:20423454;PMID:23840386;PMID:2425663;PMID:25131858;PMID:8495723;PMID:9352125;PMID:9590247 -3.4.21.39 * mesocricetus auratus 28000.0 1 PMID:8632712 -3.4.21.39 * monodelphis domestica 30000.0 2 PMID:17342483;PMID:18022236;PMID:18845543 -3.4.21.39 * mus musculus 34000.0 9 PMID:17342483;PMID:17681377;PMID:18022236;PMID:18845543;PMID:22815822;PMID:8363563 -3.4.21.39 * rattus norvegicus 30000.0 5 PMID:10082988;PMID:17342483;PMID:17681377;PMID:336834;PMID:3544704;PMID:8495723;PMID:9352125;PMID:9590247 -3.4.21.4 * albatrossia pectoralis 24000.0 1 PMID:16848554;PMID:19585993;PMID:3943597 -3.4.21.4 * alces alces 24476.0 1 PMID:1125277 -3.4.21.4 * astacus astacus 25000.0 1 PMID:18404270 -3.4.21.4 * asterias amurensis 28000.0 1 PMID:18404270 -3.4.21.4 * balistes capriscus 23200.0 1 * -3.4.21.4 * boops boops 23000.0 1 PMID:19898990 -3.4.21.4 * boreogadus saida 24011.0 1 * -3.4.21.4 * bos taurus 23312.0 3 PMID:12749769;PMID:17560535;PMID:24997448 -3.4.21.4 * cancer pagurus 26000.0 2 PMID:18395521 -3.4.21.4 * channa argus 22000.0 1 PMID:22155550 -3.4.21.4 * cirrhinus mrigala 21700.0 1 PMID:25577096 -3.4.21.4 * colossoma macropomum 23900.0 1 PMID:20438707 -3.4.21.4 * diatraea saccharalis 28700.0 1 PMID:16431280 -3.4.21.4 * eleginus gracilis 24000.0 1 PMID:14680968;PMID:19680768;PMID:22068456 -3.4.21.4 * engraulis japonicus 24000.0 1 PMID:11330348 -3.4.21.4 * epinephelus coioides 24000.0 2 PMID:14680968;PMID:19680768;PMID:22068456 -3.4.21.4 * euphausia pacifica 33000.0 2 PMID:17987272 -3.4.21.4 * felis catus 21000.0 1 PMID:9080665 -3.4.21.4 * gadus chalcogrammus 24000.0 2 PMID:17623652;PMID:17827714 -3.4.21.4 * gadus macrocephalus 24000.0 1 PMID:14680968;PMID:19680768;PMID:22068456 -3.4.21.4 * gadus morhua 27000.0 4 PMID:14680968;PMID:16879980;PMID:19680768;PMID:22068456;PMID:2707266 -3.4.21.4 * gallus gallus 24500.0 2 PMID:10480246 -3.4.21.4 * glossina longipennis 61000.0 3 PMID:7624283 -3.4.21.4 * homo sapiens 24000.0 2 PMID:16848554;PMID:17623652;PMID:17827714;PMID:19585993;PMID:3943597 -3.4.21.4 * lateolabrax japonicus 21500.0 2 PMID:21515400 -3.4.21.4 * lutjanus vitta 23000.0 1 * -3.4.21.4 * manduca sexta 25000.0 1 PMID:18404270 -3.4.21.4 * musca domestica 26600.0 1 PMID:16431280 -3.4.21.4 * oncorhynchus keta 24000.0 1 PMID:17623652;PMID:17827714 -3.4.21.4 * oncorhynchus masou 24000.0 1 PMID:14680968;PMID:19680768;PMID:22068456 -3.4.21.4 * oncorhynchus tshawytscha 28000.0 1 PMID:12031475;PMID:16458561 -3.4.21.4 * oreochromis niloticus 22390.0 1 PMID:25005977 -3.4.21.4 * oryzias latipes 28000.0 2 PMID:25483797 -3.4.21.4 * pacifastacus leniusculus 25000.0 1 PMID:10355637 -3.4.21.4 * patiria pectinifera 28000.0 1 PMID:12031475;PMID:16458561 -3.4.21.4 * penaeus japonicus 25000.0 1 PMID:18404270 -3.4.21.4 * penaeus paulensis 21700.0 1 PMID:18404270 -3.4.21.4 * penaeus vannamei 32900.0 3 PMID:18404270 -3.4.21.4 * pleurogrammus azonus 24000.0 1 PMID:14680968;PMID:19680768;PMID:22068456 -3.4.21.4 * pontastacus leptodactylus 23800.0 1 PMID:4623554 -3.4.21.4 * pterygoplichthys disjunctivus 27500.0 1 PMID:23790871 -3.4.21.4 * rattus norvegicus 24000.0 1 PMID:17623652;PMID:17827714 -3.4.21.4 * rhyzopertha dominica 24000.0 1 PMID:18404270 -3.4.21.4 * saccharopolyspora erythraea 40000.0 4 PMID:19231893 -3.4.21.4 * sarda sarda 29000.0 1 PMID:17469841;PMID:18000877 -3.4.21.4 * sardinella aurita 28800.0 1 PMID:20711672 -3.4.21.4 * sardinops caeruleus 25000.0 1 * -3.4.21.4 * sardinops melanosticta 24000.0 1 PMID:14680968;PMID:19680768;PMID:22068456 -3.4.21.4 * scomberomorus sierra 25400.0 1 * -3.4.21.4 * sepia officinalis 24000.0 1 PMID:16848554;PMID:19585993;PMID:3943597 -3.4.21.4 * sesamia nonagrioides 31000.0 1 PMID:18404270 -3.4.21.4 * silurus glanis 30100.0 1 * -3.4.21.4 * streptomyces griseus 23110.0 3 PMID:12885239;PMID:18261455;PMID:235280 -3.4.21.4 * sus scrofa 28000.0 6 PMID:19923745;PMID:4734970;PMID:7782340 -3.4.21.4 * thunnus albacares 24000.0 1 PMID:16500127 -3.4.21.4 * thunnus tonggol 24000.0 1 PMID:16848554;PMID:19585993;PMID:3943597 -3.4.21.4 * triatoma infestans 40000.0 1 PMID:18404270 -3.4.21.4 * triops sp. 31000.0 1 PMID:18404270 -3.4.21.4 * zabrotes subfasciatus 29000.0 1 PMID:17469841;PMID:18000877 -3.4.21.41 * homo sapiens 790000.0 5 PMID:17850949;PMID:20592021;PMID:6281620;PMID:869924 -3.4.21.41 * mus musculus 90000.0 1 PMID:18369152 -3.4.21.42 * homo sapiens 790000.0 15 PMID:16177097;PMID:18930415;PMID:19155518;PMID:20592021;PMID:3006672;PMID:6281620;PMID:8271968;PMID:869924 -3.4.21.43 * homo sapiens 305000.0 4 PMID:3874204;PMID:6906228 -3.4.21.45 * homo sapiens 90000.0 50 PMID:15835912;PMID:15917334;PMID:17055788;PMID:17084897;PMID:17320177;PMID:17548110;PMID:17597211;PMID:18544012;PMID:18566438;PMID:19065647;PMID:19877009;PMID:22393059;PMID:6210825;PMID:7103942 -3.4.21.45 * mus musculus 88000.0 3 PMID:18202746;PMID:8604219 -3.4.21.45 * paralabrax nebulifer 155000.0 1 PMID:2918226 -3.4.21.45 * rattus norvegicus 38000.0 2 PMID:10583609 -3.4.21.46 * homo sapiens 25000.0 6 PMID:15026276;PMID:2033278;PMID:2395435;PMID:497171;PMID:8271969;PMID:874324 -3.4.21.46 * oncorhynchus mykiss 290000.0 1 PMID:16550351 -3.4.21.46 * paralichthys olivaceus 30020.0 1 PMID:19591942 -3.4.21.47 * homo sapiens 200000.0 1 PMID:15790508 -3.4.21.47 * tachypleus tridentatus 185000.0 1 PMID:19017991 -3.4.21.48 * debaryomyces hansenii 30000.0 1 PMID:15681044 -3.4.21.48 * saccharomyces cerevisiae 73000.0 11 PMID:2663127;PMID:3325823;PMID:371621;PMID:372109;PMID:381308;PMID:4963390;PMID:7028120 -3.4.21.49 * hypoderma lineatum 28561.0 5 PMID:230030;PMID:3034899;PMID:7808473 -3.4.21.5 * bos taurus 36000.0 4 PMID:19117966;PMID:999641 -3.4.21.5 * deinagkistrodon acutus 49400.0 1 PMID:28936710 -3.4.21.5 * homo sapiens 70000.0 11 PMID:10702701;PMID:16908;PMID:17561860;PMID:19530705;PMID:20150433;PMID:20329721;PMID:4737732;PMID:836041 -3.4.21.50 * achromobacter lyticus 30000.0 4 PMID:12127482;PMID:23765612;PMID:6791693 -3.4.21.50 * lysobacter enzymogenes 30000.0 1 PMID:23765612 -3.4.21.50 * lysobacter sp. 32000.0 4 PMID:12127482;PMID:15262946 -3.4.21.50 * porphyromonas gingivalis 48000.0 1 PMID:8262362 -3.4.21.50 * pseudomonas aeruginosa 30000.0 1 PMID:15516485 -3.4.21.53 * arabidopsis thaliana 100000.0 1 PMID:17478548 -3.4.21.53 * archaeoglobus fulgidus 68200.0 1 * -3.4.21.53 * bacillus subtilis 87400.0 2 PMID:20600124 -3.4.21.53 * borreliella burgdorferi 90700.0 1 PMID:19956677 -3.4.21.53 * brevibacillus thermoruber 549000.0 4 PMID:14764100;PMID:15181012 -3.4.21.53 * escherichia coli 930000.0 18 PMID:10359771;PMID:16584195;PMID:1730246;PMID:23674680;PMID:2931432;PMID:3042779;PMID:3319736;PMID:6214787;PMID:6458037;PMID:7845219;PMID:8592469;PMID:8995294;PMID:9417111;PMID:9425059;PMID:9720920;PMID:9735326 -3.4.21.53 * homo sapiens 106000.0 3 PMID:14665623;PMID:8248235 -3.4.21.53 * mus musculus 100000.0 1 PMID:12657466 -3.4.21.53 * natrialba magadii 84269.0 1 PMID:20869220 -3.4.21.53 * pseudomonas aeruginosa 89000.0 1 PMID:18408026 -3.4.21.53 * pseudomonas amygdali pv. tabaci 88800.0 1 PMID:21904881 -3.4.21.53 * rattus norvegicus 550000.0 3 PMID:6749845;PMID:8354406 -3.4.21.53 * saccharomyces cerevisiae 850000.0 12 PMID:10359790;PMID:8354406;PMID:8592469;PMID:8626573;PMID:9724747 -3.4.21.53 * thermococcus kodakarensis 70000.0 1 PMID:12057965 -3.4.21.53 * thermococcus onnurineus 403000.0 2 PMID:20057071 -3.4.21.53 * thermoplasma acidophilum 430000.0 4 PMID:15358558;PMID:15560777 -3.4.21.53 * zea mays 977000.0 2 * -3.4.21.54 * mus musculus 26000.0 2 PMID:6337154 -3.4.21.55 * bitis gabonica 30600.0 1 PMID:3522580 -3.4.21.55 * cerastes cerastes 40500.0 6 PMID:8521839 -3.4.21.57 * spinacia oleracea 60000.0 1 PMID:16664908 -3.4.21.59 * bos taurus 360000.0 4 PMID:1515079;PMID:7845247 -3.4.21.59 * canis lupus familiaris 144000.0 6 PMID:3118812;PMID:3128177;PMID:7845247 -3.4.21.59 * homo sapiens 200000.0 25 PMID:11401583;PMID:11876641;PMID:12162961;PMID:12605678;PMID:18039527;PMID:2110591;PMID:25478999;PMID:29661938;PMID:3070298;PMID:3140898;PMID:3519608;PMID:3543004;PMID:7733867;PMID:7845247 -3.4.21.59 * mus musculus 200000.0 2 PMID:11401583;PMID:24478313 -3.4.21.59 * rattus norvegicus 160000.0 3 PMID:2036367;PMID:3066368;PMID:7845247 -3.4.21.59 * sus scrofa 120000.0 2 PMID:10824103 -3.4.21.6 * bos taurus 114000.0 6 PMID:12547804;PMID:4636332 -3.4.21.6 * mus musculus 65000.0 2 PMID:11019967;PMID:11994472 -3.4.21.60 * bothrops cotiara 29000.0 3 PMID:16647309;PMID:23619704 -3.4.21.60 * lonomia obliqua 69000.0 3 PMID:15963468;PMID:16734589 -3.4.21.60 * oxyuranus scutellatus 300000.0 5 PMID:14769787;PMID:3531198 -3.4.21.60 * pseudonaja textilis 32000.0 1 PMID:16197456 -3.4.21.61 * aeromonas sobria 65000.0 1 PMID:16487335 -3.4.21.61 * homo sapiens 75979.0 2 PMID:18052825;PMID:20172854 -3.4.21.61 * mus musculus 17640.0 1 PMID:17565604 -3.4.21.61 * rattus norvegicus 87000.0 3 PMID:17543468 -3.4.21.61 * saccharomyces cerevisiae 100000.0 1 PMID:9360297 -3.4.21.62 * alkalicoccobacillus gibsonii 27000.0 1 PMID:23179617 -3.4.21.62 * alkalimonas collagenimarina 65000.0 2 PMID:19888572 -3.4.21.62 * arthrobotrys musiformis 42000.0 1 PMID:20211028 -3.4.21.62 * arthrobotrys psychrophilus 42000.0 1 PMID:20211028 -3.4.21.62 * arthrobotrys yunnanensis 42000.0 1 PMID:20211028 -3.4.21.62 * aspergillus versicolor 41000.0 1 PMID:21632114 -3.4.21.62 * avena sativa 84000.0 2 PMID:21546909 -3.4.21.62 * bacillus amyloliquefaciens 27000.0 1 PMID:21780825 -3.4.21.62 * bacillus intermedius 28000.0 1 PMID:15170378 -3.4.21.62 * bacillus licheniformis 27000.0 1 * -3.4.21.62 * bacillus sp. (in: firmicutes) 36000.0 15 PMID:10588904;PMID:10926860;PMID:10993162;PMID:15251215;PMID:5055783;PMID:7605625;PMID:8352796 -3.4.21.62 * bacillus subtilis 62000.0 6 PMID:15649780;PMID:19902383;PMID:22069026 -3.4.21.62 * dactylella shizishanna 41300.0 1 PMID:20211028 -3.4.21.62 * geobacillus stearothermophilus 27500.0 1 * -3.4.21.62 * komagataella pastoris 37000.0 1 PMID:20472730 -3.4.21.62 * nicotiana tabacum 80000.0 1 PMID:21546909 -3.4.21.62 * oryza sativa 80000.0 1 PMID:21546909 -3.4.21.62 * penicillium cyclopium 31000.0 1 PMID:9184139 -3.4.21.62 * rhizopus microsporus var. rhizopodiformis 33000.0 1 PMID:17127629 -3.4.21.62 * sarocladium strictum 34000.0 1 PMID:23530047 -3.4.21.62 * shouchella clausii 55000.0 5 PMID:15988584;PMID:20541512;PMID:21307308 -3.4.21.62 * streptococcus suis 170000.0 2 PMID:20146817;PMID:21030165 -3.4.21.62 * thermococcus kodakarensis 68630.0 6 PMID:16946475;PMID:20100702 -3.4.21.62 * trichoderma harzianum 69000.0 2 PMID:24500477 -3.4.21.62 * trichomonas vaginalis 101000.0 2 PMID:20602853 -3.4.21.63 * aspergillus candidus 23000.0 2 * -3.4.21.63 * aspergillus flavus 27180.0 3 * -3.4.21.63 * aspergillus fumigatus 30000.0 2 PMID:16732450 -3.4.21.63 * aspergillus nidulans 35000.0 1 PMID:23334783 -3.4.21.63 * aspergillus oryzae 35000.0 5 PMID:18226921;PMID:242254;PMID:4197025 -3.4.21.63 * aspergillus sojae 25500.0 1 * -3.4.21.63 * aspergillus terreus 16000.0 1 PMID:28324360 -3.4.21.64 * parengyodontium album 28930.0 2 PMID:4373242 -3.4.21.64 * serratia sp. (in: enterobacteria) 65500.0 2 PMID:16367747 -3.4.21.64 * tritirachium album limber 18500.0 1 PMID:9055209 -3.4.21.65 * malbranchea pulchella 33000.0 5 PMID:1012007;PMID:4208643;PMID:4429868 -3.4.21.66 * laceyella sacchari 28000.0 2 PMID:24084004;PMID:24646757 -3.4.21.66 * streptomyces rectus var. proteolyticus 29100.0 4 PMID:4373436;PMID:5082135 -3.4.21.66 * thermoactinomyces vulgaris 37400.0 5 PMID:5082135;PMID:7028036;PMID:749455;PMID:749456 -3.4.21.67 * escherichia coli 150000.0 4 PMID:6339474;PMID:7043205 -3.4.21.68 * bos taurus 80000.0 2 PMID:9730836 -3.4.21.68 * homo sapiens 147000.0 23 PMID:1368681;PMID:14694433;PMID:15033993;PMID:15652516;PMID:18922856;PMID:21120587;PMID:21442553;PMID:22018738;PMID:23676904;PMID:2413894;PMID:25886739;PMID:6337343;PMID:8507663;PMID:9201906;PMID:9730836 -3.4.21.68 * mus musculus 66000.0 1 * -3.4.21.68 * rattus norvegicus 68000.0 1 PMID:18493852 -3.4.21.69 * bos taurus 55000.0 6 PMID:1245477 -3.4.21.69 * homo sapiens 62000.0 3 PMID:16681644;PMID:17580306;PMID:22072231 -3.4.21.7 * homo sapiens 92000.0 9 PMID:138064;PMID:21136135;PMID:22987920;PMID:23071827;PMID:25576865 -3.4.21.7 * oryctolagus cuniculus 86000.0 2 PMID:138065 -3.4.21.70 * bos taurus 35000.0 1 * -3.4.21.70 * homo sapiens 35000.0 5 PMID:234742;PMID:6378180;PMID:7165710 -3.4.21.70 * sus scrofa 35000.0 1 * -3.4.21.71 * bos taurus 29000.0 2 PMID:11838546;PMID:7647093 -3.4.21.71 * rattus norvegicus 29000.0 2 PMID:11838546;PMID:7647093 -3.4.21.72 * haemophilus influenzae 130000.0 5 PMID:18165266;PMID:19393662;PMID:29318516;PMID:3896849 -3.4.21.72 * neisseria gonorrhoeae 106000.0 1 PMID:3027577 -3.4.21.72 * neisseria meningitidis 170000.0 3 PMID:20386581;PMID:25161279 -3.4.21.72 * neisseria meningitidis serogroup b 107000.0 1 PMID:26343028 -3.4.21.72 * prevotella melaninogenica 62000.0 1 PMID:6147309 -3.4.21.73 * homo sapiens 55000.0 7 PMID:1515091;PMID:16916471;PMID:16928215;PMID:17118695;PMID:19370078;PMID:21858203;PMID:25555911 -3.4.21.73 * mus musculus 52000.0 1 PMID:20177776 -3.4.21.73 * rattus norvegicus 45000.0 7 PMID:6682102;PMID:7981665 -3.4.21.73 * sus scrofa 50000.0 1 PMID:19168722 -3.4.21.74 * bothrops alternatus 31500.0 2 PMID:20184912 -3.4.21.74 * bothrops asper 41500.0 3 PMID:1011993 -3.4.21.74 * bothrops atrox 30000.0 1 PMID:17933591 -3.4.21.74 * bothrops jararaca 24000.0 1 PMID:33940046 -3.4.21.74 * bothrops marajoensis 43000.0 4 PMID:1011993 -3.4.21.74 * bothrops moojeni 41500.0 4 PMID:1011993 -3.4.21.74 * bothrops pirajai 49000.0 2 PMID:24719874 -3.4.21.74 * calloselasma rhodostoma 35400.0 1 PMID:1011992 -3.4.21.74 * crotalus atrox 35000.0 3 PMID:8024586 -3.4.21.74 * daboia russelii russelii 333571.0 9 PMID:18249434;PMID:24520323 -3.4.21.74 * gloydius shedaoensis 90000.0 1 PMID:19639313 -3.4.21.74 * macrovipera lebetinus 37000.0 2 PMID:11910177 -3.4.21.74 * protobothrops flavoviridis 28000.0 2 PMID:17803962 -3.4.21.74 * trimeresurus albolabris 47900.0 4 PMID:17346761;PMID:22610139 -3.4.21.75 * homo sapiens 55000.0 1 PMID:19956642 -3.4.21.75 * mus musculus 96000.0 3 PMID:10958789;PMID:7845205 -3.4.21.75 * synthetic construct 96000.0 2 PMID:18544638 -3.4.21.76 * homo sapiens 36000.0 5 PMID:16182289;PMID:16488976;PMID:16598772;PMID:17158864;PMID:7845237;PMID:9328566 -3.4.21.76 * mus musculus 30000.0 3 PMID:16182289;PMID:16488976;PMID:21120490 -3.4.21.77 * homo sapiens 200000.0 20 PMID:12496845;PMID:16598740;PMID:18051307;PMID:18535354;PMID:19079621;PMID:19551556;PMID:19636406;PMID:19937596;PMID:20102753;PMID:2422647;PMID:2436946;PMID:3691515;PMID:9180162 -3.4.21.78 * homo sapiens 30000.0 2 PMID:10666226;PMID:3257574 -3.4.21.78 * mus musculus 60000.0 2 PMID:3545816 -3.4.21.79 * equus caballus 35000.0 1 PMID:17604123;PMID:20027633 -3.4.21.79 * homo sapiens 61000.0 11 PMID:10914010;PMID:15596356;PMID:17604123;PMID:17765974;PMID:18675462;PMID:1985927;PMID:20027633;PMID:20536562;PMID:23573299;PMID:24291445 -3.4.21.79 * mus musculus 33000.0 4 PMID:10914010;PMID:17599099;PMID:9480818 -3.4.21.81 * streptomyces griseus 18600.0 3 PMID:10712933;PMID:4218101 -3.4.21.82 * bacillus intermedius 26500.0 1 PMID:14640964 -3.4.21.82 * streptomyces griseus 22000.0 3 PMID:1959600;PMID:3149277 -3.4.21.83 * escherichia coli 81860.0 6 PMID:10569938;PMID:11872480;PMID:11900553;PMID:1769955;PMID:240839;PMID:776612 -3.4.21.83 * leishmania amazonensis 98000.0 2 PMID:17530480;PMID:35703092 -3.4.21.83 * salmonella enterica 78970.0 1 PMID:12029050 -3.4.21.83 * serratia proteamaculans 78000.0 2 PMID:19916930;PMID:21585325 -3.4.21.83 * trypanosoma brucei 160000.0 3 PMID:15811340;PMID:19819899 -3.4.21.83 * trypanosoma cruzi 189000.0 4 PMID:18029266;PMID:22276197 -3.4.21.83 * xenorhabdus nematophila 60000.0 1 PMID:11872480;PMID:776612 -3.4.21.84 * limulus polyphemus 123000.0 3 PMID:2016264;PMID:3512266 -3.4.21.84 * tachypleus sp. 80000.0 2 PMID:2016264;PMID:3512266 -3.4.21.85 * tachypleus tridentatus 64000.0 7 PMID:3519594 -3.4.21.86 * limulus sp. 38190.0 1 PMID:2266134 -3.4.21.86 * tachypleus tridentatus 54000.0 3 PMID:4030738 -3.4.21.88 * [bacillus thuringiensis] serovar konkukian 50000.0 1 PMID:10671501;PMID:31056420 -3.4.21.88 * escherichia coli 100000.0 6 PMID:10671501;PMID:1494343;PMID:16701697;PMID:31056420;PMID:7013987;PMID:7845214 -3.4.21.88 * mycobacterium tuberculosis 27600.0 1 PMID:19118359 -3.4.21.88 * pectobacterium carotovorum 22320.0 1 PMID:1494343 -3.4.21.88 * pseudomonas aeruginosa 22506.0 1 PMID:1494343 -3.4.21.88 * pseudomonas putida 22147.0 1 PMID:1494343 -3.4.21.88 * salmonella enterica subsp. enterica serovar typhimurium 22307.0 1 PMID:1494343 -3.4.21.88 * synechocystis sp. 29300.0 1 PMID:18555801 -3.4.21.89 * [bacillus] caldolyticus 21000.0 1 PMID:9194173 -3.4.21.89 * bacillus amyloliquefaciens 21000.0 1 PMID:9194173 -3.4.21.89 * bacillus licheniformis 21000.0 1 PMID:9194173 -3.4.21.89 * bacillus subtilis 63000.0 3 PMID:10982814;PMID:9194173 -3.4.21.89 * canis lupus familiaris 25000.0 5 PMID:1740185;PMID:7845216;PMID:9194173 -3.4.21.89 * escherichia coli 640000.0 18 PMID:10891078;PMID:10982814;PMID:1455520;PMID:1740185;PMID:2549048;PMID:3522590;PMID:6282859;PMID:6361480;PMID:7845215;PMID:9194173;PMID:9464569;PMID:9823901 -3.4.21.89 * gallus gallus 57000.0 9 PMID:1740185;PMID:2549048;PMID:7845216;PMID:9194173;PMID:9464569 -3.4.21.89 * leptolyngbya laminosa 22000.0 1 PMID:9194173 -3.4.21.89 * methanocaldococcus jannaschii 24000.0 1 PMID:9194173 -3.4.21.89 * methanococcus voltae 24600.0 2 PMID:14526003 -3.4.21.89 * mycobacterium tuberculosis 32000.0 1 PMID:9194173 -3.4.21.89 * neurospora crassa 57000.0 7 PMID:1740185;PMID:7845216 -3.4.21.89 * plasmodium falciparum 42000.0 1 PMID:16489263 -3.4.21.89 * plasmodium knowlesi 37000.0 1 PMID:16489263 -3.4.21.89 * plasmodium yoelii 41000.0 1 PMID:16489263 -3.4.21.89 * pseudomonas aeruginosa 32103.0 5 PMID:22730125;PMID:9642237 -3.4.21.89 * pseudomonas fluorescens 32000.0 1 PMID:1455520 -3.4.21.89 * rattus norvegicus 57000.0 7 PMID:1740185;PMID:7845216 -3.4.21.89 * saccharomyces cerevisiae 57000.0 15 PMID:1740185;PMID:7845216;PMID:9194173 -3.4.21.89 * salmonella enterica subsp. enterica serovar typhimurium 36000.0 1 PMID:1455520 -3.4.21.89 * staphylococcus aureus 21000.0 1 PMID:9194173 -3.4.21.9 * bos taurus 150000.0 9 PMID:15025141;PMID:15129728;PMID:15248027;PMID:17703946;PMID:2658218;PMID:889800 -3.4.21.9 * homo sapiens 296000.0 7 PMID:21884736;PMID:2192931;PMID:22723979;PMID:23436726;PMID:23917033;PMID:945736 -3.4.21.9 * oryzias latipes 44000.0 2 PMID:17438297 -3.4.21.9 * struthio camelus 127000.0 2 * -3.4.21.9 * sus scrofa 316000.0 5 PMID:4200635;PMID:945736 -3.4.21.91 * dengue virus 45000.0 4 PMID:24228881;PMID:24352016 -3.4.21.91 * dengue virus type 4 74000.0 1 PMID:17942558 -3.4.21.91 * flavivirus sp. 70000.0 1 PMID:2174669 -3.4.21.91 * hepacivirus hominis 35000.0 2 PMID:17239391 -3.4.21.92 * arabidopsis thaliana 350000.0 9 PMID:11278690;PMID:16980539 -3.4.21.92 * escherichia coli 700000.0 18 PMID:10359771;PMID:1783205;PMID:20637416;PMID:2197275;PMID:2967816;PMID:3049606;PMID:7845217;PMID:8226769;PMID:8226770 -3.4.21.92 * lathyrus oleraceus 29000.0 1 PMID:11556794 -3.4.21.92 * mycobacterium tuberculosis 300000.0 1 PMID:25933022 -3.4.21.92 * plasmodium falciparum 43000.0 2 PMID:20887733 -3.4.21.92 * staphylococcus aureus 304000.0 2 PMID:24106749 -3.4.21.92 * synechococcus elongatus 300000.0 5 PMID:17371875;PMID:19237538 -3.4.21.92 * thermus thermophilus 300000.0 1 PMID:31517045 -3.4.21.93 * homo sapiens 94000.0 4 PMID:16644867;PMID:17595246 -3.4.21.93 * mus musculus 87000.0 10 PMID:11006274;PMID:15283695;PMID:15358360;PMID:16644867;PMID:17565604;PMID:9182540;PMID:9813073 -3.4.21.93 * rattus norvegicus 87000.0 3 PMID:17240044;PMID:17543468;PMID:18771713 -3.4.21.94 * mus musculus 66000.0 2 PMID:10799554 -3.4.21.94 * penaeus monodon 70400.0 1 PMID:22634957 -3.4.21.94 * rattus norvegicus 75000.0 4 PMID:17543468;PMID:19142196 -3.4.21.95 * daboia russelii 29000.0 6 PMID:3053712;PMID:7043192 -3.4.21.95 * daboia siamensis 29000.0 1 PMID:20054136 -3.4.21.95 * macrovipera lebetinus 30000.0 2 PMID:11910177;PMID:9920400 -3.4.21.96 * lacticaseibacillus paracasei 300000.0 4 PMID:1564442 -3.4.21.96 * lacticaseibacillus rhamnosus 170000.0 1 PMID:27585760 -3.4.21.96 * lactobacillus helveticus 180000.0 1 PMID:16960054 -3.4.21.96 * lactococcus lactis 250000.0 5 PMID:10103227;PMID:10788376;PMID:1610200;PMID:7945226;PMID:8309942 -3.4.21.96 * treponema denticola 72000.0 1 PMID:18279185 -3.4.21.97 * human betaherpesvirus 5 57000.0 6 PMID:17287260;PMID:8631772;PMID:9882568 -3.4.21.98 * hepacivirus hominis 70000.0 11 PMID:10425166;PMID:10529230;PMID:12182815;PMID:17239391;PMID:21766396;PMID:8626434;PMID:8794305;PMID:8861916 -3.4.21.98 * west nile virus 32000.0 2 PMID:15494419;PMID:16229682 -3.4.21.99 * halocynthia roretzi 40000.0 5 PMID:11856325;PMID:6365918 -3.4.22.1 * ancylostoma caninum 28000.0 1 PMID:21925175 -3.4.22.1 * angiostrongylus cantonensis 60000.0 4 PMID:21344211;PMID:24929149;PMID:26221074 -3.4.22.1 * apostichopus japonicus 36800.0 3 PMID:27847342 -3.4.22.1 * artemia sp. 68000.0 1 PMID:7047162 -3.4.22.1 * bos taurus 31000.0 6 PMID:14569304;PMID:2223009;PMID:510307;PMID:6003 -3.4.22.1 * bubalus bubalis 28300.0 4 PMID:3023303;PMID:8936819;PMID:9594426 -3.4.22.1 * capra hircus 29000.0 2 PMID:9305539 -3.4.22.1 * clonorchis sinensis 38000.0 4 PMID:24985496 -3.4.22.1 * cristaria plicata 38550.0 1 PMID:29981453 -3.4.22.1 * cynoglossus semilaevis 36250.0 1 PMID:21959146 -3.4.22.1 * cyprinus carpio 30000.0 3 * -3.4.22.1 * dorytheuthis bleekeri 13600.0 1 * -3.4.22.1 * fasciola gigantica 36900.0 2 PMID:23811052 -3.4.22.1 * fasciola hepatica 28790.0 1 PMID:9538862 -3.4.22.1 * fundulus heteroclitus 36000.0 2 PMID:16141306 -3.4.22.1 * gallus gallus 28000.0 2 PMID:2907328 -3.4.22.1 * haemonchus contortus 43000.0 1 PMID:19401141 -3.4.22.1 * heliocidaris crassispina 22000.0 1 * -3.4.22.1 * hemicentrotus pulcherrimus 29000.0 1 * -3.4.22.1 * homo sapiens 43000.0 17 PMID:11115496;PMID:15950230;PMID:16362335;PMID:16918357;PMID:18472965;PMID:18598236;PMID:19331819;PMID:20107207;PMID:23189279;PMID:3196286;PMID:4824207;PMID:627216 -3.4.22.1 * larimichthys crocea 36310.0 1 PMID:24705226 -3.4.22.1 * macaca fuscata 24000.0 1 PMID:4847211;PMID:6725239 -3.4.22.1 * meretrix meretrix 63000.0 2 PMID:20853148 -3.4.22.1 * mus musculus 400000.0 6 PMID:14585834;PMID:19544382 -3.4.22.1 * naegleria fowleri 38400.0 2 PMID:24832815 -3.4.22.1 * necator americanus 55000.0 2 PMID:18501979 -3.4.22.1 * nicotiana benthamiana 30000.0 1 PMID:17697096 -3.4.22.1 * oreochromis niloticus 36191.0 1 PMID:29730007 -3.4.22.1 * oryctolagus cuniculus 28800.0 4 PMID:3223923;PMID:3338470;PMID:4062307;PMID:4847211;PMID:6725239 -3.4.22.1 * penaeus vannamei 26900.0 1 PMID:21946097 -3.4.22.1 * procambarus clarkii 36400.0 1 PMID:27417230 -3.4.22.1 * radopholus similis 55000.0 1 PMID:24929149;PMID:26221074 -3.4.22.1 * rattus norvegicus 43000.0 4 PMID:108278;PMID:16497156;PMID:42540 -3.4.22.1 * scomber australasicus 28000.0 1 * -3.4.22.1 * scophthalmus maximus 36000.0 1 PMID:25326658 -3.4.22.1 * sus scrofa 33000.0 6 PMID:108278;PMID:3722202;PMID:7334002 -3.4.22.1 * tetrahymena pyriformis 23000.0 1 PMID:6406222 -3.4.22.1 * toxoplasma gondii 62200.0 2 PMID:12000756 -3.4.22.1 * trichobilharzia regenti 38700.0 24 PMID:15950230;PMID:20107207 -3.4.22.1 * uronema marinum 38980.0 4 PMID:16172011 -3.4.22.10 * streptococcus pyogenes 160000.0 19 PMID:15557629;PMID:15797242;PMID:16329996;PMID:17029726;PMID:18174338;PMID:18227168;PMID:19237546;PMID:19362485;PMID:20158613;PMID:22050223;PMID:24799625 -3.4.22.10 * streptococcus pyogenes m1 gas 40000.0 2 PMID:18072207 -3.4.22.10 * streptococcus sp. 33590.0 4 PMID:22163320 -3.4.22.14 * actinidia arguta 24000.0 1 PMID:21123873;PMID:22039217 -3.4.22.14 * actinidia chinensis 30000.0 10 PMID:19397706;PMID:20061012;PMID:21123873;PMID:22039217;PMID:4664227;PMID:5506167;PMID:7003158;PMID:9564807 -3.4.22.14 * actinidia deliciosa 30000.0 4 PMID:21123873;PMID:22039217;PMID:22227218;PMID:24633720 -3.4.22.15 * agama stellio stellio 34000.0 1 PMID:11002190 -3.4.22.15 * apostichopus japonicus 63000.0 1 PMID:18540081 -3.4.22.15 * clonorchis sinensis 41500.0 5 PMID:19308452;PMID:22406988 -3.4.22.15 * clostridioides difficile 80000.0 4 PMID:17693508;PMID:21784932 -3.4.22.15 * cristaria plicata 37650.0 1 PMID:25038281 -3.4.22.15 * cyprinus carpio 30000.0 2 PMID:2361361;PMID:9467867 -3.4.22.15 * decapterus maruadsi 30000.0 1 * -3.4.22.15 * dosidicus gigas 24000.0 2 PMID:16960372 -3.4.22.15 * fasciola gigantica 47600.0 4 PMID:23820262;PMID:25701317 -3.4.22.15 * gallus gallus 27000.0 2 PMID:3676277 -3.4.22.15 * helicoverpa armigera 47000.0 1 PMID:17201774 -3.4.22.15 * homo sapiens 60000.0 19 PMID:12818188;PMID:17147449;PMID:17671649;PMID:18221013;PMID:18619973;PMID:19291794;PMID:19343278;PMID:19589362;PMID:20002173;PMID:20230872;PMID:20370324;PMID:20506357;PMID:24889867;PMID:3977867;PMID:8282126 -3.4.22.15 * hypophthalmichthys molitrix 30000.0 1 PMID:17147449;PMID:17671649 -3.4.22.15 * ictalurus punctatus 38100.0 1 PMID:19084602 -3.4.22.15 * manduca sexta 24000.0 1 PMID:19361282 -3.4.22.15 * misgurnus mizolepis 62000.0 1 PMID:20401701 -3.4.22.15 * mus musculus 40000.0 3 PMID:18410501;PMID:19589362;PMID:20230872 -3.4.22.15 * oncorhynchus keta 30000.0 1 PMID:2361361;PMID:9467867 -3.4.22.15 * oryctolagus cuniculus 29000.0 4 PMID:1426527;PMID:3223923;PMID:6421281;PMID:7390982 -3.4.22.15 * papio ursinus 37000.0 3 PMID:8529021 -3.4.22.15 * paramecium tetraurelia 27000.0 3 PMID:8665938 -3.4.22.15 * patiria pectinifera 61000.0 1 PMID:23221686 -3.4.22.15 * rattus norvegicus 35000.0 9 PMID:1426527;PMID:16960372;PMID:3402618;PMID:3666143;PMID:3688881;PMID:3759937;PMID:4038303;PMID:6421281 -3.4.22.15 * schistosoma mansoni 24300.0 1 PMID:8577349 -3.4.22.15 * spodoptera frugiperda 405000.0 2 PMID:16274658 -3.4.22.15 * theromyzon tessulatum 24000.0 1 PMID:18177937 -3.4.22.15 * toxoplasma gondii 32000.0 2 PMID:19111576 -3.4.22.15 * triatoma brasiliensis 37100.0 4 PMID:22100382 -3.4.22.16 * bos taurus 28000.0 2 PMID:22582844;PMID:6746670;PMID:8713750 -3.4.22.16 * cyprinus carpio 29000.0 2 PMID:1499287;PMID:9206588 -3.4.22.16 * fasciola gigantica 75000.0 6 PMID:19632187 -3.4.22.16 * homo sapiens 30000.0 6 PMID:12565709;PMID:15127951;PMID:15627059;PMID:3342889;PMID:7043200 -3.4.22.16 * hordeum vulgare 37000.0 1 PMID:3901004 -3.4.22.16 * ictalurus punctatus 36600.0 1 PMID:19084602 -3.4.22.16 * mus musculus 28000.0 4 PMID:17500053;PMID:22022579;PMID:22582844 -3.4.22.16 * oryctolagus cuniculus 30000.0 3 PMID:12565709;PMID:659418;PMID:7043200 -3.4.22.16 * rattus norvegicus 37100.0 7 PMID:12565709;PMID:3128174;PMID:3691815;PMID:6370990;PMID:7043200 -3.4.22.16 * sus scrofa 25000.0 1 PMID:6746670;PMID:8713750 -3.4.22.2 * carica papaya 42000.0 7 PMID:16997546;PMID:19272620;PMID:5470818 -3.4.22.24 * rattus norvegicus 35000.0 4 PMID:2885716;PMID:7248311 -3.4.22.25 * carica papaya 24000.0 4 PMID:25038693;PMID:2591528;PMID:7845231 -3.4.22.26 * mus musculus 10000.0 1 PMID:1575750 -3.4.22.26 * oryctolagus cuniculus 68000.0 1 PMID:3935163 -3.4.22.27 * bos taurus 24000.0 5 PMID:15334187;PMID:1801734;PMID:2690828;PMID:3814093;PMID:8444861;PMID:8612629;PMID:8845771 -3.4.22.27 * canis lupus familiaris 26000.0 1 PMID:12651112 -3.4.22.27 * homo sapiens 36000.0 7 PMID:17081125;PMID:17391985;PMID:18347141;PMID:19101991;PMID:21982919;PMID:3814093;PMID:8444861;PMID:8612629;PMID:8845771 -3.4.22.27 * ictalurus punctatus 36700.0 1 PMID:18817983 -3.4.22.27 * mus musculus 24000.0 1 PMID:19487544 -3.4.22.27 * oryctolagus cuniculus 30500.0 2 PMID:3223923 -3.4.22.27 * rattus norvegicus 37000.0 1 PMID:18700000 -3.4.22.27 * saimiri boliviensis 26000.0 1 PMID:12651112 -3.4.22.28 * ectropis obliqua virus 34000.0 1 PMID:22534091 -3.4.22.28 * enterovirus c 25000.0 4 PMID:10680961;PMID:17002308;PMID:8457209 -3.4.22.28 * foot-and-mouth disease virus 25000.0 2 PMID:15858279 -3.4.22.28 * hepatovirus a 26000.0 4 PMID:18407505;PMID:7853510 -3.4.22.28 * human rhinovirus sp. 20000.0 1 PMID:17305557 -3.4.22.28 * norwalk virus 18000.0 1 PMID:25275273 -3.4.22.29 * coxsackievirus 17000.0 2 PMID:7845234;PMID:8338854 -3.4.22.29 * enterovirus a71 20000.0 1 PMID:23973886 -3.4.22.29 * enterovirus c 17000.0 2 PMID:24066065;PMID:2831385;PMID:9681985 -3.4.22.29 * hepatovirus a 21000.0 1 PMID:15164619 -3.4.22.29 * human rhinovirus sp. 30000.0 5 PMID:24066065;PMID:7845234;PMID:8338854;PMID:9681985 -3.4.22.29 * rhinovirus c2 11000.0 1 PMID:24937088 -3.4.22.3 * ficus anthelmintica 26500.0 1 * -3.4.22.3 * ficus carica 27000.0 10 PMID:18991449;PMID:19482042;PMID:25849510;PMID:26083455;PMID:4407343 -3.4.22.3 * ficus elastica 50000.0 1 * -3.4.22.3 * ficus insipida 26100.0 6 PMID:16657243;PMID:5423375;PMID:5758541 -3.4.22.3 * ficus johannis 25000.0 1 * -3.4.22.30 * carica papaya 40000.0 5 PMID:12767335;PMID:16283547;PMID:19156482;PMID:240390 -3.4.22.31 * ananas comosus 38200.0 4 PMID:23082082;PMID:3196029;PMID:8053898 -3.4.22.32 * ananas comosus 57000.0 27 PMID:1012011;PMID:1124936;PMID:23921698;PMID:3196029;PMID:4044551;PMID:4462742;PMID:4761326;PMID:5073324;PMID:5083269;PMID:7779262;PMID:9619588 -3.4.22.33 * ananas comosus 50000.0 15 PMID:11577981;PMID:24965557;PMID:25212320;PMID:36144767;PMID:4044551;PMID:5073324;PMID:956152 -3.4.22.33 * bromelia fastuosa 25000.0 1 PMID:16454675 -3.4.22.33 * bromelia karatas 97000.0 2 PMID:30263775 -3.4.22.33 * bromelia pinguin 97000.0 2 PMID:30263775 -3.4.22.34 * blastocystis hominis 45200.0 3 PMID:19915007;PMID:27609526 -3.4.22.34 * blastocystis sp. bw-2009a 30000.0 1 PMID:19915007 -3.4.22.34 * bos taurus 56000.0 7 PMID:11983426;PMID:18449874;PMID:28528272 -3.4.22.34 * branchiostoma belcheri 37000.0 1 PMID:19552625 -3.4.22.34 * dictyocaulus viviparus 50000.0 2 PMID:28942744 -3.4.22.34 * glycine max 45000.0 1 PMID:1731337 -3.4.22.34 * haemaphysalis longicornis 49630.0 6 PMID:17681230;PMID:18222467 -3.4.22.34 * haemonchus contortus 75000.0 2 PMID:16650340 -3.4.22.34 * homo sapiens 56000.0 9 PMID:10488118;PMID:19196156;PMID:22902879;PMID:9821970 -3.4.22.34 * hordeum vulgare 41000.0 1 PMID:23669572 -3.4.22.34 * opisthorchis viverrini 47000.0 1 PMID:18619888 -3.4.22.34 * papaver rhoeas 53000.0 3 PMID:20740374 -3.4.22.34 * phaseolus vulgaris 53400.0 4 PMID:6385962;PMID:9874222 -3.4.22.34 * ricinus communis 37000.0 1 PMID:1743299 -3.4.22.34 * saccharum sp. 60000.0 1 PMID:22721948 -3.4.22.34 * schistosoma japonicum 50000.0 2 * -3.4.22.34 * schistosoma mansoni 50000.0 5 PMID:18280591 -3.4.22.34 * sus scrofa 35300.0 4 PMID:10383426;PMID:9065484 -3.4.22.34 * vigna aconitifolia 33000.0 1 * -3.4.22.34 * vigna radiata 23500.0 2 PMID:891531 -3.4.22.35 * entamoeba histolytica 112000.0 15 PMID:10417646;PMID:10542062;PMID:15659066;PMID:17513563;PMID:18824105;PMID:24769005;PMID:25680771;PMID:2869098;PMID:2898937;PMID:2902852 -3.4.22.36 * galleria mellonella 17000.0 1 PMID:22229544 -3.4.22.36 * homo sapiens 45000.0 4 PMID:18828051;PMID:19004566;PMID:22833538 -3.4.22.36 * lymantria dispar 33304.0 3 * -3.4.22.36 * mus musculus 45000.0 2 PMID:19004566;PMID:22403439 -3.4.22.36 * rattus norvegicus 45000.0 1 PMID:19004566 -3.4.22.36 * trichoplusia ni 35000.0 3 PMID:19027856 -3.4.22.37 * porphyromonas gingivalis 185000.0 23 PMID:1527017;PMID:16237103;PMID:16923905;PMID:18349372;PMID:19691286;PMID:23279840;PMID:23499434;PMID:23583629;PMID:32582160;PMID:7831206;PMID:7857299;PMID:9673019;PMID:9705298 -3.4.22.38 * canis lupus familiaris 37000.0 1 PMID:22171552 -3.4.22.38 * homo sapiens 43000.0 21 PMID:12182837;PMID:17935853;PMID:18818416;PMID:20206119;PMID:21982919;PMID:7576232;PMID:7818555;PMID:8567669;PMID:8647860;PMID:9153258 -3.4.22.38 * mus musculus 32000.0 1 PMID:18338784 -3.4.22.38 * oryctolagus cuniculus 37000.0 1 PMID:8874809 -3.4.22.38 * paralichthys olivaceus 50000.0 1 PMID:19666132 -3.4.22.38 * sebastes schlegelii 36400.0 1 PMID:32001355 -3.4.22.39 * human adenovirus sp. 23100.0 2 PMID:23043136;PMID:23043138 -3.4.22.39 * unidentified adenovirus 25500.0 2 PMID:8336124 -3.4.22.40 * aspergillus niger 72000.0 1 * -3.4.22.40 * gallus gallus 400000.0 2 PMID:9151954 -3.4.22.40 * homo sapiens 310000.0 5 PMID:19286660;PMID:3109467;PMID:8639621 -3.4.22.40 * oryctolagus cuniculus 300000.0 5 PMID:19286660;PMID:3109467;PMID:3117099 -3.4.22.40 * rattus norvegicus 300000.0 4 PMID:16472072;PMID:19286660;PMID:3109467 -3.4.22.40 * streptomyces verticillus 300000.0 1 * -3.4.22.41 * clonorchis sinensis 24000.0 1 PMID:19932715 -3.4.22.41 * homo sapiens 70000.0 5 PMID:16963053;PMID:23684953;PMID:9822672 -3.4.22.41 * mizuhopecten yessoensis 70180.0 1 PMID:29879509 -3.4.22.41 * mus musculus 31000.0 1 PMID:16508006 -3.4.22.41 * opisthorchis viverrini 47000.0 3 PMID:19308250;PMID:20070308 -3.4.22.41 * paralichthys olivaceus 52880.0 2 PMID:19545641 -3.4.22.41 * teladorsagia circumcincta 41097.0 1 PMID:16387304 -3.4.22.42 * homo sapiens 35880.0 2 PMID:7929457 -3.4.22.42 * oplegnathus fasciatus 36900.0 1 PMID:21767649 -3.4.22.43 * homo sapiens 52000.0 14 PMID:10029531;PMID:21982919;PMID:22100277;PMID:22393040;PMID:22562303;PMID:9727401 -3.4.22.43 * lepeophtheirus salmonis 42151.0 1 * -3.4.22.44 * chilli veinal mottle virus 29000.0 1 PMID:22989753;PMID:23096592 -3.4.22.44 * clover yellow vein virus 23000.0 1 PMID:9648226 -3.4.22.44 * plum pox virus 29000.0 1 PMID:22989753;PMID:23096592 -3.4.22.45 * bean common mosaic virus 110000.0 2 PMID:32251956 -3.4.22.45 * lettuce mosaic virus 138000.0 2 PMID:12684502 -3.4.22.45 * papaya ringspot virus 52000.0 2 PMID:19672730 -3.4.22.45 * potato virus y 50000.0 1 PMID:8609483 -3.4.22.45 * soybean mosaic virus 43000.0 1 * -3.4.22.45 * tobacco vein mottling virus 35000.0 1 * -3.4.22.45 * zucchini yellow mosaic virus 126000.0 2 PMID:21593273;PMID:21871010 -3.4.22.46 * cucumber vein yellowing virus 113600.0 1 PMID:25562450 -3.4.22.46 * foot-and-mouth disease virus 41400.0 5 PMID:23756127;PMID:8057448;PMID:9472614 -3.4.22.46 * lactococcus lactis 77500.0 2 PMID:24914961 -3.4.22.46 * porcine reproductive and respiratory syndrome virus 41400.0 3 PMID:23756127 -3.4.22.47 * porphyromonas gingivalis 105000.0 10 PMID:18349372;PMID:19691286;PMID:7831206;PMID:7890369;PMID:8276827;PMID:9538207;PMID:9673019 -3.4.22.48 * staphylococcus aureus 40000.0 4 PMID:23798534;PMID:35708833 -3.4.22.48 * staphylococcus epidermidis 19832.0 1 PMID:11767947 -3.4.22.49 * drosophila melanogaster 72900.0 1 PMID:11581162 -3.4.22.49 * homo sapiens 233000.0 4 PMID:12672959;PMID:19758559;PMID:31729382;PMID:38667185 -3.4.22.49 * saccharomyces cerevisiae 200000.0 1 PMID:25822502 -3.4.22.49 * trypanosoma brucei 126000.0 1 PMID:19183276 -3.4.22.50 * autographa californica nucleopolyhedrovirus 37000.0 2 * -3.4.22.50 * choristoneura fumiferana multiple nucleopolyhedrovirus 27500.0 1 PMID:24086357 -3.4.22.51 * trypanosoma congolense 33000.0 1 PMID:12108538;PMID:12183554 -3.4.22.51 * trypanosoma cruzi 60000.0 11 PMID:12108538;PMID:12183554;PMID:12460772;PMID:14552859;PMID:17298440;PMID:18342408;PMID:18620619;PMID:18793639;PMID:2407295;PMID:8454586 -3.4.22.51 * trypanosoma rangeli 40000.0 7 PMID:19683503 -3.4.22.52 * anolis carolinensis 80000.0 1 PMID:20223856 -3.4.22.52 * cavia porcellus 80000.0 1 PMID:20716611;PMID:22432027;PMID:25575026 -3.4.22.52 * danio rerio 80000.0 1 PMID:20223856 -3.4.22.52 * gallus gallus 76000.0 2 PMID:2834353 -3.4.22.52 * homo sapiens 80000.0 10 PMID:19215300;PMID:19342550;PMID:19538725;PMID:19793101;PMID:20716611;PMID:22432027;PMID:25575026;PMID:2581621;PMID:3019407 -3.4.22.52 * mus musculus 80000.0 4 PMID:19393648;PMID:19734364;PMID:20223856;PMID:20716611;PMID:22432027;PMID:25575026;PMID:25660447 -3.4.22.52 * notamacropus eugenii 80000.0 1 PMID:20223856 -3.4.22.52 * ornithorhynchus anatinus 80000.0 1 PMID:20223856 -3.4.22.52 * oryctolagus cuniculus 80000.0 2 PMID:19215300;PMID:2581621 -3.4.22.52 * plasmodium falciparum 46000.0 1 PMID:19861123 -3.4.22.52 * rattus norvegicus 110000.0 14 PMID:19393648;PMID:19659897;PMID:19734364;PMID:19751724;PMID:19793101;PMID:19833151;PMID:23212179;PMID:25660447;PMID:6278869;PMID:6306001;PMID:7031044 -3.4.22.52 * sus scrofa 83000.0 5 PMID:20223856;PMID:2839229;PMID:6088477;PMID:6093770 -3.4.22.52 * taeniopygia guttata 80000.0 1 PMID:20223856 -3.4.22.52 * xenopus laevis 80000.0 1 PMID:20223856 -3.4.22.53 * bos mutus 100000.0 1 PMID:20300663 -3.4.22.53 * bos taurus 80000.0 4 PMID:20123702;PMID:20372982;PMID:2581621;PMID:2834353 -3.4.22.53 * dicentrarchus labrax 124000.0 3 PMID:14961288 -3.4.22.53 * gallus gallus 80000.0 2 PMID:20372982;PMID:2581621;PMID:2834353 -3.4.22.53 * homo sapiens 80000.0 2 * -3.4.22.53 * macaca fuscata 110000.0 3 PMID:6094523 -3.4.22.53 * mus musculus 80000.0 3 PMID:19723289;PMID:20854926;PMID:22427650;PMID:22432027;PMID:23613308 -3.4.22.53 * oryctolagus cuniculus 80000.0 2 PMID:20372982;PMID:2581621;PMID:2834353 -3.4.22.53 * pelophylax ridibundus 105000.0 3 PMID:8207386 -3.4.22.53 * penaeus monodon 160000.0 2 * -3.4.22.53 * rattus norvegicus 115000.0 18 PMID:12014988;PMID:19226146;PMID:19659897;PMID:19833151;PMID:19861418;PMID:20035707;PMID:20211186;PMID:20854926;PMID:21145877;PMID:22427650;PMID:22432027;PMID:23613308;PMID:6278869;PMID:6306001 -3.4.22.53 * struthio camelus 84000.0 1 PMID:11854033 -3.4.22.53 * sus scrofa 80000.0 2 PMID:2839229;PMID:6088477 -3.4.22.53 * tilapia sp. 110000.0 3 PMID:20372982;PMID:2581621;PMID:2834353;PMID:6094523 -3.4.22.54 * homo sapiens 282000.0 6 PMID:15660530;PMID:16107503;PMID:19215300;PMID:19386580;PMID:32200007 -3.4.22.54 * mus musculus 94000.0 2 PMID:19483197;PMID:25389288 -3.4.22.54 * nephrops norvegicus 65900.0 1 PMID:19642014 -3.4.22.54 * rattus norvegicus 94084.0 6 PMID:16107503;PMID:19144634;PMID:2555341;PMID:34638951 -3.4.22.55 * apostichopus japonicus 43930.0 1 PMID:26687532 -3.4.22.55 * homo sapiens 51000.0 6 PMID:15865942;PMID:16777994;PMID:20026395;PMID:23840868;PMID:32438737 -3.4.22.55 * mus musculus 48000.0 3 PMID:16481596 -3.4.22.55 * rattus norvegicus 45000.0 1 PMID:23815625 -3.4.22.56 * danio rerio 33000.0 3 PMID:16842121 -3.4.22.56 * homo sapiens 35000.0 3 PMID:18553063;PMID:19142017 -3.4.22.56 * macrobrachium nipponense 56300.0 1 PMID:28159694 -3.4.22.56 * solanum tuberosum 75000.0 1 PMID:25486023 -3.4.22.57 * homo sapiens 35000.0 1 PMID:25695505 -3.4.22.58 * homo sapiens 55000.0 2 PMID:16893518 -3.4.22.59 * holothuria leucospilota 38570.0 1 PMID:29890217 -3.4.22.59 * homo sapiens 63070.0 7 PMID:19558602;PMID:19694615;PMID:20682790;PMID:22018804;PMID:23916608 -3.4.22.59 * mus musculus 32000.0 1 PMID:22649225 -3.4.22.59 * rattus norvegicus 24000.0 1 PMID:15749343 -3.4.22.59 * takifugu obscurus 34090.0 1 * -3.4.22.6 * carica papaya 36400.0 7 PMID:19156482;PMID:240390;PMID:2920009 -3.4.22.60 * homo sapiens 250000.0 7 PMID:16123041;PMID:16352606;PMID:16427675;PMID:21157428 -3.4.22.61 * homo sapiens 57000.0 16 PMID:10508785;PMID:15209560;PMID:16211292;PMID:16225956;PMID:19142017;PMID:20332233;PMID:20498002;PMID:21157428 -3.4.22.61 * mytilus coruscus 56180.0 1 PMID:25150535 -3.4.22.61 * mytilus galloprovincialis 55820.0 1 PMID:25150535 -3.4.22.61 * rattus norvegicus 57000.0 2 PMID:19878704 -3.4.22.62 * homo sapiens 69200.0 8 PMID:19118655;PMID:19308735;PMID:8900201;PMID:9890966 -3.4.22.62 * sus scrofa 52000.0 1 PMID:18840507 -3.4.22.63 * channa striata 103500.0 2 PMID:23253492 -3.4.22.63 * homo sapiens 58900.0 2 PMID:10187817;PMID:19166881 -3.4.22.65 * dermatophagoides farinae 34000.0 4 PMID:15753904;PMID:18545812;PMID:8829528 -3.4.22.65 * dermatophagoides pteronyssinus 60000.0 9 PMID:15753904;PMID:19152967;PMID:19175594;PMID:20226507;PMID:21904913 -3.4.22.66 * chiba virus 20600.0 1 PMID:15845259 -3.4.22.66 * southampton virus 19000.0 1 PMID:10073687 -3.4.22.67 * zingiber officinale 34800.0 3 PMID:23625608;PMID:25475843 -3.4.22.67 * zingiber ottensii 32500.0 3 PMID:21442550 -3.4.22.68 * saccharomyces cerevisiae 31000.0 1 PMID:15263846 -3.4.22.69 * severe acute respiratory syndrome-related coronavirus 34000.0 3 PMID:16647061;PMID:20420403;PMID:23452147 -3.4.22.7 * asclepias curassavica 23590.0 7 PMID:15517987;PMID:19204833;PMID:19679160 -3.4.22.7 * asclepias glaucescens 24400.0 8 * -3.4.22.7 * asclepias syriaca 24000.0 5 PMID:36921;PMID:6988008 -3.4.22.7 * gomphocarpus fruticosus subsp. fruticosus 23406.0 1 PMID:19455353 -3.4.22.70 * bacillus anthracis 23000.0 1 PMID:15968076 -3.4.22.70 * staphylococcus aureus 25000.0 4 PMID:11371637;PMID:20178374;PMID:21991306 -3.4.22.70 * staphylococcus sp. 27000.0 1 PMID:21494692 -3.4.22.70 * streptococcus pneumoniae 24810.0 1 PMID:19433540 -3.4.22.70 * streptococcus pneumoniae d39 24810.0 1 PMID:19433540 -3.4.22.70 * streptococcus pneumoniae tigr4 24810.0 1 PMID:19433540 -3.4.22.8 * clostridium perfringens 38000.0 1 PMID:19850615 -3.4.22.8 * hathewaya histolytica 50000.0 14 PMID:20940055;PMID:4971659;PMID:6391922;PMID:762145 -3.4.23.1 * albatrossia pectoralis 35000.0 1 PMID:17493857 -3.4.23.1 * anas platyrhynchos 35000.0 1 PMID:2253484 -3.4.23.1 * canis lupus familiaris 35000.0 1 PMID:796626 -3.4.23.1 * capra hircus 40000.0 1 PMID:16433961 -3.4.23.1 * coturnix japonica 36000.0 1 PMID:6766746 -3.4.23.1 * gallus gallus 43000.0 3 PMID:4578760;PMID:4897245;PMID:4918122 -3.4.23.1 * homo sapiens 35000.0 1 PMID:240833 -3.4.23.1 * lateolabrax japonicus 35000.0 2 PMID:21167955 -3.4.23.1 * monopterus albus 36000.0 2 PMID:21140210 -3.4.23.1 * ovis aries 34000.0 1 PMID:15546 -3.4.23.1 * pelodiscus sinensis 43000.0 1 PMID:8889828 -3.4.23.1 * rattus norvegicus 32000.0 1 PMID:36374 -3.4.23.1 * shewanella amazonensis 50000.0 1 PMID:21749650 -3.4.23.1 * sus scrofa 35000.0 1 PMID:4860638 -3.4.23.1 * trematomus bernacchii 34250.0 1 PMID:17976195 -3.4.23.12 * nepenthes distillatoria 51000.0 7 PMID:15035659 -3.4.23.15 * bos taurus 44000.0 1 PMID:108284;PMID:2666611;PMID:38848;PMID:4344349;PMID:6360207;PMID:6767720;PMID:6812648;PMID:7042710;PMID:718949 -3.4.23.15 * canis lupus familiaris 42000.0 2 PMID:2666611 -3.4.23.15 * homo sapiens 59000.0 13 PMID:108284;PMID:2203348;PMID:2666611;PMID:3280035;PMID:3533063;PMID:363168;PMID:38848;PMID:4344349;PMID:6360207;PMID:6767720;PMID:6790533;PMID:6812648;PMID:7041895;PMID:7042710;PMID:718949;PMID:8382130 -3.4.23.15 * mus musculus 44000.0 6 PMID:108284;PMID:2666611;PMID:38848;PMID:4344349;PMID:6337154;PMID:6360207;PMID:6767720;PMID:6812055;PMID:6812648;PMID:7042710;PMID:718949 -3.4.23.15 * rattus norvegicus 48000.0 4 PMID:108284;PMID:16865234;PMID:2666611;PMID:38848;PMID:4344349;PMID:6360207;PMID:6767720;PMID:6812648;PMID:7042710;PMID:718949;PMID:8382130 -3.4.23.15 * sus scrofa 59000.0 2 PMID:108284;PMID:2666611;PMID:363168;PMID:38848;PMID:4344349;PMID:6360207;PMID:6767720;PMID:6812648;PMID:7041895;PMID:7042710;PMID:718949 -3.4.23.16 * human immunodeficiency virus 1 10870.0 2 PMID:8652592 -3.4.23.17 * bos taurus 70000.0 4 PMID:2840973;PMID:2987247;PMID:3021739;PMID:7488064 -3.4.23.17 * saccharomyces cerevisiae 68000.0 1 PMID:8389368 -3.4.23.18 * aspergillus fumigatus 37500.0 1 PMID:7019156 -3.4.23.18 * aspergillus luchuensis 35000.0 1 * -3.4.23.18 * aspergillus niger 50000.0 2 PMID:31374272 -3.4.23.18 * aspergillus oryzae 2000000.0 11 PMID:12595261;PMID:15618633;PMID:239702;PMID:25177;PMID:29561;PMID:8138 -3.4.23.18 * aspergillus phoenicis 34500.0 3 * -3.4.23.19 * aspergillus niger 22260.0 1 PMID:9561230 -3.4.23.2 * albatrossia pectoralis 31000.0 1 PMID:17493857 -3.4.23.2 * boreogadus saida 40000.0 1 * -3.4.23.2 * sus scrofa 57200.0 5 PMID:7574716 -3.4.23.20 * penicillium camemberti 33500.0 1 * -3.4.23.20 * penicillium duponti 41590.0 3 PMID:2287;PMID:4699217 -3.4.23.20 * penicillium janthinellum 34000.0 4 PMID:1012008;PMID:10850809 -3.4.23.20 * penicillium roqueforti 33400.0 1 * -3.4.23.21 * rhizopus arrhizus 37600.0 3 PMID:7766059 -3.4.23.21 * rhizopus microsporus var. chinensis 34340.0 2 PMID:3283113 -3.4.23.21 * rhizopus niveus 40300.0 1 * -3.4.23.22 * cryphonectria parasitica 37500.0 4 PMID:21972967 -3.4.23.23 * amylomyces rouxii 16000.0 1 PMID:21127856 -3.4.23.23 * aspergillus oryzae 47000.0 1 PMID:21127856 -3.4.23.23 * mucor circinelloides 33000.0 1 PMID:21127856 -3.4.23.23 * mucor renninus 35000.0 2 PMID:21127856 -3.4.23.23 * mucor sp. 33500.0 2 PMID:10408332 -3.4.23.23 * penicillium duponti 41000.0 1 PMID:21127856 -3.4.23.23 * rhizomucor miehei 42000.0 4 PMID:4775436;PMID:5450445;PMID:9561231 -3.4.23.23 * rhizomucor pusillus 44000.0 4 PMID:21127856 -3.4.23.23 * rhizopus arrhizus 34000.0 1 PMID:21127856 -3.4.23.24 * candida albicans 86000.0 41 PMID:12372437;PMID:19649403;PMID:19880183;PMID:21535228;PMID:21646240;PMID:3513844;PMID:3914793;PMID:5729955;PMID:6203988;PMID:7018586;PMID:8360612;PMID:8407785 -3.4.23.24 * candida olea 30900.0 2 PMID:3312474 -3.4.23.24 * candida parapsilosis 36000.0 1 PMID:21953587 -3.4.23.24 * metschnikowia pulcherrima 36500.0 2 PMID:7766170 -3.4.23.25 * debaryomyces hansenii 55000.0 2 PMID:18423921 -3.4.23.25 * saccharomyces cerevisiae 54000.0 10 PMID:10930843;PMID:2663127;PMID:7002931;PMID:7041826;PMID:8297512 -3.4.23.26 * cladosporium sp. 32000.0 1 * -3.4.23.26 * rhodotorula glutinis 30000.0 3 * -3.4.23.29 * irpex lacteus 39000.0 7 * -3.4.23.3 * bos taurus 32800.0 1 PMID:6800788 -3.4.23.3 * capra hircus 39000.0 1 PMID:10392458 -3.4.23.3 * homo sapiens 40000.0 3 PMID:20231168 -3.4.23.3 * macaca fuscata 27000.0 1 PMID:12157 -3.4.23.3 * rattus norvegicus 41206.0 1 PMID:3780741 -3.4.23.3 * sus scrofa 41400.0 1 PMID:5339544 -3.4.23.30 * trametes coccinea 34000.0 1 * -3.4.23.31 * scytalidium lignicola 43000.0 5 * -3.4.23.32 * ganoderma lucidum 36000.0 1 * -3.4.23.32 * lentinula edodes 40000.0 2 * -3.4.23.32 * scytalidium lignicola 22000.0 3 PMID:6370989 -3.4.23.34 * aquarana catesbeiana 90000.0 4 PMID:8188640;PMID:8346912 -3.4.23.34 * cavia porcellus 82000.0 5 PMID:1644829;PMID:7545776 -3.4.23.34 * homo sapiens 92000.0 22 PMID:15294281;PMID:18996084;PMID:1998500;PMID:3058118;PMID:3314869;PMID:6993448;PMID:7545776;PMID:8188640;PMID:8325357;PMID:8346912;PMID:8463263;PMID:8540320;PMID:8540336;PMID:8540338;PMID:9363769 -3.4.23.34 * meloidogyne incognita 41502.0 1 PMID:18952081 -3.4.23.34 * rattus norvegicus 98000.0 5 PMID:3058036;PMID:3058118;PMID:3314869 -3.4.23.35 * saccharomyces cerevisiae 200000.0 1 * -3.4.23.36 * escherichia coli 18144.0 3 PMID:6374664;PMID:7674920 -3.4.23.36 * streptococcus gordonii 17400.0 1 PMID:20233933 -3.4.23.38 * plasmodium falciparum 40000.0 2 PMID:2007860;PMID:21521654 -3.4.23.39 * plasmodium falciparum 84000.0 4 PMID:19906540;PMID:32385863;PMID:7935597 -3.4.23.4 * bos taurus 40000.0 8 PMID:16433961;PMID:20524840;PMID:25278015;PMID:8936042 -3.4.23.4 * bubalus bubalis 36000.0 1 PMID:18975968 -3.4.23.4 * camelus dromedarius 45000.0 5 PMID:16488399;PMID:25837439 -3.4.23.4 * capra hircus 42000.0 2 PMID:16890468 -3.4.23.4 * felis catus 36000.0 1 PMID:6810938 -3.4.23.4 * rhizomucor pusillus 44000.0 1 * -3.4.23.4 * rhizopus microsporus 37000.0 1 PMID:25035104 -3.4.23.40 * ananas comosus 55230.0 1 PMID:23838125 -3.4.23.40 * cannabis sativa 20000.0 1 PMID:8540324 -3.4.23.40 * cucumis sativus 42000.0 1 PMID:8540324 -3.4.23.40 * cucurbita maxima 42000.0 1 PMID:8540324 -3.4.23.40 * cynara cardunculus 52600.0 10 PMID:15677463;PMID:24986551;PMID:8654427 -3.4.23.40 * cynara cardunculus var. scolymus 46000.0 8 PMID:15649509 -3.4.23.40 * fagopyrum esculentum 28000.0 1 PMID:8540324 -3.4.23.40 * helianthus annuus 39000.0 3 PMID:11330695 -3.4.23.40 * hordeum vulgare 48000.0 6 PMID:24186727;PMID:8540324 -3.4.23.40 * nelumbo nucifera 37000.0 1 PMID:8540324 -3.4.23.40 * nepenthes macfarlanei 59000.0 1 PMID:8540324 -3.4.23.40 * nicotiana tabacum 40000.0 1 PMID:8540324 -3.4.23.40 * oryza sativa 65000.0 2 PMID:8540324 -3.4.23.40 * solanum lycopersicum 37000.0 1 PMID:8540324 -3.4.23.40 * theobroma cacao 45000.0 3 PMID:8540324 -3.4.23.40 * triticum aestivum 89000.0 5 PMID:24212424;PMID:8540324 -3.4.23.40 * triticum durum x haynaldia villosa 66000.0 1 PMID:8540324 -3.4.23.41 * ogataea angusta 200000.0 5 PMID:22162039 -3.4.23.41 * saccharomyces cerevisiae 180000.0 4 PMID:7779785;PMID:9417119 -3.4.23.41 * trichoderma asperellum 42300.0 2 PMID:23677580 -3.4.23.42 * saccharolobus solfataricus 120000.0 1 PMID:19508193 -3.4.23.42 * sulfolobus acidocaldarius 51000.0 6 PMID:2104843 -3.4.23.45 * homo sapiens 65000.0 7 PMID:11083922;PMID:12065613;PMID:12618121;PMID:17113083 -3.4.23.45 * mus musculus 56000.0 1 PMID:12740567 -3.4.23.45 * rattus norvegicus 73000.0 1 PMID:17113083 -3.4.23.46 * homo sapiens 70000.0 2 PMID:11015226;PMID:18177262 -3.4.23.46 * rattus norvegicus 65000.0 1 PMID:19376202 -3.4.23.47 * human immunodeficiency virus 2 22000.0 1 PMID:8106448 -3.4.23.48 * yersinia pestis 35000.0 4 PMID:10024583 -3.4.23.49 * escherichia coli 180000.0 8 PMID:10651827;PMID:11327829;PMID:17711325;PMID:3056908;PMID:3278297 -3.4.23.5 * asterias rubens 45000.0 2 PMID:22155551 -3.4.23.5 * bos taurus 55000.0 5 PMID:1567870;PMID:4266584;PMID:5549596 -3.4.23.5 * callosobruchus maculatus 43000.0 1 PMID:19446566 -3.4.23.5 * clupea harengus 39000.0 2 PMID:11207447 -3.4.23.5 * ctenopharyngodon idella 43106.0 2 PMID:23009921 -3.4.23.5 * cyprinus carpio 36000.0 1 PMID:7584842 -3.4.23.5 * danio rerio 46000.0 2 PMID:23107604 -3.4.23.5 * gallus gallus 45000.0 3 PMID:4266584;PMID:5419752 -3.4.23.5 * homarus americanus 50000.0 3 PMID:20169386;PMID:20817002;PMID:21298030 -3.4.23.5 * homarus gammarus 36400.0 1 PMID:20169386 -3.4.23.5 * homo sapiens 56000.0 33 PMID:16242956;PMID:16354654;PMID:17188016;PMID:18396902;PMID:18433155;PMID:19807669;PMID:19854241;PMID:20493920;PMID:20817002;PMID:21298030;PMID:23871913;PMID:25402676;PMID:25663755;PMID:26086961;PMID:3145753;PMID:4208234;PMID:5419752;PMID:831834 -3.4.23.5 * lamellidens corrianus 43000.0 1 PMID:24365170;PMID:8925451 -3.4.23.5 * lethenteron camtschaticum 42772.0 1 PMID:25450905 -3.4.23.5 * mus musculus 95000.0 6 PMID:14706;PMID:19913584 -3.4.23.5 * musca domestica 36510.0 1 PMID:19815068 -3.4.23.5 * oryctolagus cuniculus 52000.0 4 PMID:4266584;PMID:5549596;PMID:6818962 -3.4.23.5 * patiria pectinifera 50000.0 1 PMID:17977858 -3.4.23.5 * rattus norvegicus 54000.0 13 PMID:18840968;PMID:19995700;PMID:20045930;PMID:446474;PMID:6360207 -3.4.23.5 * scophthalmus maximus 42700.0 4 PMID:18948209 -3.4.23.5 * sepia officinalis 37500.0 1 PMID:20843039 -3.4.23.5 * silurus asotus 37000.0 1 PMID:11821259 -3.4.23.5 * spisula solidissima 36700.0 1 * -3.4.23.5 * struthio camelus 45000.0 3 PMID:21055883 -3.4.23.5 * sus scrofa 100000.0 12 PMID:115868;PMID:6743251;PMID:7118874;PMID:9713704 -3.4.23.5 * tilapia sp. 55000.0 2 PMID:4266584 -3.4.23.5 * todarodes pacificus 36500.0 2 PMID:15050524 -3.4.23.5 * tribolium castaneum 22000.0 1 PMID:8673082 -3.4.23.5 * xenopus laevis 43000.0 1 PMID:24365170;PMID:8925451 -3.4.23.50 * homo sapiens 43000.0 3 PMID:18076964;PMID:9860826 -3.4.23.51 * escherichia coli 17000.0 2 PMID:15667279;PMID:7851435 -3.4.23.51 * escherichia coli k-12 17000.0 1 PMID:19720045 -3.4.23.52 * methanococcus voltae 25900.0 1 PMID:14622420 -3.4.23.52 * sulfolobus acidocaldarius 28000.0 1 PMID:25102813 -3.4.24.1 * bothrops atrox 60000.0 1 PMID:31561469 -3.4.24.1 * crotalus adamanteus 8000.0 1 PMID:23313448 -3.4.24.1 * crotalus atrox 30000.0 8 PMID:10620350;PMID:1520324;PMID:1616487;PMID:2745407;PMID:3101740;PMID:3913334 -3.4.24.1 * crotalus ruber ruber 60050.0 6 PMID:2949699 -3.4.24.1 * crotalus scutulatus scutulatus 21821.0 4 PMID:24522289 -3.4.24.11 * bos taurus 90000.0 1 PMID:7028098 -3.4.24.11 * canis lupus familiaris 104000.0 2 PMID:8489505 -3.4.24.11 * drosophila melanogaster 120000.0 2 PMID:19880729 -3.4.24.11 * homo sapiens 97000.0 4 PMID:17021406;PMID:17906676;PMID:23831521;PMID:25089527 -3.4.24.11 * mus musculus 320000.0 2 PMID:7041888 -3.4.24.11 * rattus norvegicus 92000.0 1 PMID:1669834 -3.4.24.11 * sus scrofa 320000.0 5 PMID:3539105;PMID:3888721;PMID:6349615;PMID:6419725 -3.4.24.12 * echinoidea 47700.0 1 * -3.4.24.12 * hemicentrotus pulcherrimus 135000.0 4 PMID:9188724 -3.4.24.12 * paracentrotus lividus 65000.0 3 PMID:2167841;PMID:2925668 -3.4.24.12 * strongylocentrotus intermedius 45000.0 2 PMID:488095 -3.4.24.12 * strongylocentrotus purpuratus 150000.0 6 PMID:1012003;PMID:1182129;PMID:20058;PMID:2341403;PMID:5561747 -3.4.24.13 * haemophilus influenzae 137000.0 3 PMID:16085369;PMID:6384245;PMID:6416146 -3.4.24.13 * neisseria gonorrhoeae 114000.0 4 PMID:103829;PMID:3127382 -3.4.24.13 * prevotella melaninogenica 62000.0 1 PMID:6147309 -3.4.24.13 * streptococcus suis 154000.0 1 PMID:19619964 -3.4.24.14 * bos taurus 500000.0 5 PMID:16046392;PMID:2500439;PMID:8157670 -3.4.24.14 * gallus gallus 500000.0 2 PMID:2500439;PMID:3918028;PMID:568000;PMID:8157670 -3.4.24.14 * homo sapiens 132000.0 2 PMID:16771712 -3.4.24.15 * bacillus licheniformis 150000.0 2 * -3.4.24.15 * bos taurus 184000.0 2 PMID:2289016 -3.4.24.15 * herpetomonas pessoai 66000.0 1 PMID:19126269 -3.4.24.15 * homo sapiens 78000.0 2 PMID:16644202;PMID:18430865 -3.4.24.15 * mus musculus 78000.0 1 PMID:16904239 -3.4.24.15 * rattus norvegicus 78300.0 6 PMID:1355047;PMID:15955058;PMID:19755481;PMID:2261476;PMID:7674943 -3.4.24.15 * sus scrofa 70000.0 3 PMID:1355047;PMID:8297391 -3.4.24.16 * homo sapiens 63000.0 1 PMID:9257187 -3.4.24.16 * rattus norvegicus 80202.0 6 PMID:1355047;PMID:3409880;PMID:7592986;PMID:8425555 -3.4.24.16 * sus scrofa 75000.0 3 PMID:1355047;PMID:1905921;PMID:8425555 -3.4.24.17 * homo sapiens 57000.0 4 PMID:20215736;PMID:3095317 -3.4.24.17 * oryctolagus cuniculus 24500.0 2 PMID:6347180 -3.4.24.18 * homo sapiens 6400000.0 6 PMID:17976009;PMID:25617491;PMID:3261961;PMID:3261962;PMID:7710697 -3.4.24.18 * mus musculus 6400000.0 24 PMID:10837482;PMID:11301339;PMID:12437102;PMID:17976009;PMID:1894622;PMID:25617491;PMID:2690825;PMID:3105525;PMID:7041888;PMID:7674930;PMID:8195177 -3.4.24.18 * rattus norvegicus 350000.0 17 PMID:12399461;PMID:2690825;PMID:3105525;PMID:7674930;PMID:8063866;PMID:8195177 -3.4.24.19 * gallus gallus 110000.0 5 PMID:3905801;PMID:41715;PMID:7041964 -3.4.24.19 * homo sapiens 82900.0 2 PMID:16716085 -3.4.24.19 * mus musculus 125000.0 4 PMID:2689170;PMID:3533405 -3.4.24.19 * strongylocentrotus purpuratus 71890.0 1 * -3.4.24.19 * xenopus laevis 110200.0 4 * -3.4.24.20 * armillaria mellea 16650.0 3 PMID:23849 -3.4.24.20 * grifola frondosa 20000.0 1 PMID:8749321 -3.4.24.20 * myxobacter sp. 17000.0 2 PMID:4343825 -3.4.24.20 * pleurotus ostreatus 18000.0 1 PMID:8541645 -3.4.24.21 * ancylostoma ceylanicum 26700.0 1 PMID:23376445 -3.4.24.21 * astacus astacus 23000.0 2 PMID:3548817;PMID:7674929 -3.4.24.21 * brugia malayi 50000.0 1 PMID:19883650 -3.4.24.21 * cyprinus carpio 23000.0 1 PMID:9153232 -3.4.24.21 * haemonchus contortus 50000.0 1 PMID:19883650 -3.4.24.21 * paralithodes camtschaticus 22180.0 1 PMID:16842111 -3.4.24.21 * steinernema carpocapsae 35200.0 1 PMID:20670659 -3.4.24.22 * homo sapiens 56000.0 2 PMID:20215736 -3.4.24.23 * homo sapiens 28000.0 4 PMID:10965033;PMID:1390635 -3.4.24.23 * mus musculus 28000.0 2 PMID:16769909 -3.4.24.23 * rattus norvegicus 28000.0 6 PMID:10660581;PMID:3182822 -3.4.24.24 * bos taurus 72000.0 3 PMID:15030172 -3.4.24.24 * homo sapiens 72000.0 24 PMID:12023034;PMID:12509986;PMID:17435175;PMID:17452564;PMID:17943549;PMID:18200629;PMID:19189315;PMID:19760465;PMID:19912382;PMID:22001844;PMID:2269296;PMID:2834383;PMID:8380993;PMID:9054449;PMID:9368077 -3.4.24.24 * oryctolagus cuniculus 72000.0 4 PMID:2994741 -3.4.24.24 * rattus norvegicus 72000.0 2 PMID:17437609 -3.4.24.25 * vibrio cholerae serotype o1 45000.0 2 PMID:21054266 -3.4.24.25 * vibrio proteolyticus 35000.0 2 PMID:1012006 -3.4.24.26 * acinetobacter junii 33000.0 1 PMID:25895519 -3.4.24.26 * legionella pneumophila 60780.0 1 PMID:2110146 -3.4.24.26 * pseudomonas aeruginosa 100000.0 34 PMID:12654643;PMID:15830941;PMID:16186360;PMID:1744034;PMID:1791748;PMID:18331590;PMID:19332295;PMID:2107256;PMID:2123831;PMID:22326423;PMID:2493453;PMID:2509368;PMID:25979480;PMID:2842313;PMID:3079727;PMID:30837358;PMID:6815099;PMID:7674924;PMID:8320217;PMID:8454342;PMID:8825775 -3.4.24.27 * bacillus thermoproteolyticus 37500.0 9 PMID:10400334;PMID:10651278;PMID:12454500;PMID:16169746;PMID:17616558;PMID:22648563;PMID:5040648;PMID:5954368;PMID:9374873;PMID:9827548 -3.4.24.27 * geobacillus stearothermophilus 34400.0 1 PMID:23831195 -3.4.24.27 * halobacillus sp. 35000.0 1 PMID:23357731 -3.4.24.27 * staphylococcus pseudintermedius 55170.0 2 PMID:18769737 -3.4.24.28 * bacillus amyloliquefaciens 37000.0 2 PMID:23813340 -3.4.24.28 * bacillus cereus 26000.0 1 PMID:25802851 -3.4.24.28 * bacillus intermedius 19000.0 1 PMID:21166648 -3.4.24.28 * bacillus nematocida 40000.0 1 PMID:16775750 -3.4.24.28 * geobacillus stearothermophilus 35000.0 3 PMID:11946772;PMID:18176791 -3.4.24.28 * hathewaya histolytica 34000.0 1 PMID:22286040 -3.4.24.28 * paenibacillus polymyxa 34000.0 1 PMID:22286040 -3.4.24.28 * priestia megaterium 35300.0 1 PMID:15677446 -3.4.24.29 * staphylococcus aureus 38000.0 4 PMID:4632562;PMID:711676;PMID:99180 -3.4.24.29 * staphylococcus warneri 57600.0 1 PMID:27008278 -3.4.24.3 * clostridium perfringens 120000.0 1 PMID:24754251 -3.4.24.3 * hathewaya histolytica 147200.0 28 PMID:11121400;PMID:12682007;PMID:14240635;PMID:184822;PMID:22099748;PMID:22685155;PMID:4297964;PMID:4322486;PMID:4340512;PMID:6095892;PMID:6266487;PMID:9013490 -3.4.24.3 * pseudoalteromonas mariniglutinosa 74000.0 1 * -3.4.24.3 * streptomyces sp. 100000.0 3 PMID:2822678;PMID:3023269 -3.4.24.3 * vibrio alginolyticus 110000.0 2 * -3.4.24.3 * vibrio parahaemolyticus 64000.0 2 PMID:10206692 -3.4.24.3 * vibrio sp. 105000.0 3 PMID:210785 -3.4.24.3 * vibrio vulnificus 35000.0 1 * -3.4.24.30 * enterococcus faecalis 33000.0 5 PMID:2536744;PMID:6779709 -3.4.24.30 * streptococcus thermophilus 169000.0 3 PMID:11055922;PMID:4451671 -3.4.24.31 * streptomyces cacaoi 60000.0 1 PMID:2341042 -3.4.24.31 * streptomyces naraensis 37100.0 1 PMID:5073323 -3.4.24.32 * achromobacter lyticus 22000.0 5 PMID:7674960;PMID:9685723 -3.4.24.32 * lysobacter enzymogenes 19100.0 1 PMID:7674960 -3.4.24.32 * lysobacter gummosus 19100.0 1 PMID:24518560 -3.4.24.33 * pseudomonas fragi 27000.0 3 PMID:7674963 -3.4.24.34 * homo sapiens 85000.0 3 PMID:2159879;PMID:2164002 -3.4.24.34 * mus musculus 85000.0 2 PMID:17375198 -3.4.24.35 * bos taurus 92000.0 2 PMID:16858614 -3.4.24.35 * canis lupus familiaris 92000.0 1 PMID:19150571 -3.4.24.35 * gallus gallus 230000.0 2 PMID:22349360 -3.4.24.35 * homo sapiens 228300.0 41 PMID:10644727;PMID:16440426;PMID:16624282;PMID:17298441;PMID:17437609;PMID:17452564;PMID:17939964;PMID:18237197;PMID:18688174;PMID:19084125;PMID:19105967;PMID:19122290;PMID:19144199;PMID:19148478;PMID:19197071;PMID:19212645;PMID:19234219;PMID:19259351;PMID:19267840;PMID:19429378;PMID:19576641;PMID:19608737;PMID:19625121;PMID:19801842;PMID:20096265;PMID:20334687;PMID:20507826;PMID:20514206;PMID:21266053;PMID:22343748;PMID:25360794;PMID:2551898;PMID:9179302 -3.4.24.35 * mus musculus 105000.0 11 PMID:18006877;PMID:19105967;PMID:19122290;PMID:19135426;PMID:19144199;PMID:19171847;PMID:19200854;PMID:19234219;PMID:19259351;PMID:19267840;PMID:19429378;PMID:19576641;PMID:19587312;PMID:19631748;PMID:19646426;PMID:19801842;PMID:19962294;PMID:9179302 -3.4.24.35 * rattus norvegicus 150000.0 16 PMID:16624282;PMID:17053025;PMID:17298441;PMID:17437609;PMID:17939964;PMID:18809469;PMID:19105967;PMID:19122290;PMID:19144199;PMID:19234219;PMID:19259351;PMID:19267840;PMID:19320892;PMID:19330523;PMID:19429378;PMID:19556529;PMID:19576641;PMID:19801842;PMID:9179302 -3.4.24.35 * trypanosoma cruzi 97000.0 2 PMID:20138866 -3.4.24.36 * herpetomonas pessoai 66000.0 1 PMID:20359946 -3.4.24.36 * leishmania chagasi 59177.0 3 PMID:18067978 -3.4.24.36 * leishmania donovani 62950.0 1 PMID:19238247 -3.4.24.36 * leishmania major 63000.0 4 PMID:10464270;PMID:7675788 -3.4.24.37 * debaryomyces hansenii 68000.0 2 PMID:18423921 -3.4.24.37 * saccharomyces cerevisiae 86000.0 3 PMID:3886641 -3.4.24.38 * chlamydomonas reinhardtii 67000.0 6 PMID:3319620;PMID:3888980 -3.4.24.39 * aeromonas salmonicida 19000.0 1 PMID:18952802 -3.4.24.39 * aspergillus oryzae 19800.0 4 PMID:10446194;PMID:12728984 -3.4.24.39 * aspergillus sojae 19020.0 1 * -3.4.24.40 * citrobacter freundii 51000.0 4 PMID:4212288 -3.4.24.40 * deinococcus radiodurans 85000.0 1 PMID:18590838 -3.4.24.40 * dickeya chrysanthemi 51100.0 3 PMID:1494344;PMID:2211513 -3.4.24.40 * flavobacterium sp. ys-80-122 49000.0 1 PMID:20221715 -3.4.24.40 * pseudomonas aeruginosa 57000.0 6 PMID:10641797;PMID:13956585;PMID:16221305;PMID:1827596;PMID:4199986;PMID:6791404;PMID:7674934;PMID:9748654 -3.4.24.40 * pseudomonas fluorescens 47000.0 3 PMID:18511140;PMID:9058196 -3.4.24.40 * pseudomonas sp. 48770.0 4 PMID:11004544 -3.4.24.40 * serratia marcescens 60000.0 10 PMID:23911872;PMID:37166;PMID:383155;PMID:6380155;PMID:7487035;PMID:7674934 -3.4.24.40 * serratia sp. e-15 50630.0 2 PMID:3016665;PMID:7674934 -3.4.24.41 * crotalus atrox 29300.0 4 PMID:210790;PMID:3060135;PMID:7674933 -3.4.24.42 * crotalus atrox 27900.0 6 PMID:210790;PMID:2745407;PMID:7674933 -3.4.24.42 * crotalus ruber ruber 25500.0 2 PMID:2949699 -3.4.24.43 * crotalus atrox 23500.0 2 PMID:3167016 -3.4.24.44 * crotalus atrox 25700.0 9 PMID:210790;PMID:3060135;PMID:7674933;PMID:9637732 -3.4.24.45 * crotalus atrox 64000.0 2 PMID:6375570;PMID:7674933 -3.4.24.46 * crotalus adamanteus 24000.0 4 PMID:309470 -3.4.24.47 * crotalus horridus horridus 57000.0 3 PMID:6340728 -3.4.24.48 * crotalus ruber ruber 25000.0 2 PMID:2081731;PMID:2949699 -3.4.24.49 * bothrops atrox 60000.0 1 PMID:31561469 -3.4.24.49 * bothrops jararaca 49870.0 6 PMID:6819660 -3.4.24.50 * bothrops jararaca 23000.0 1 PMID:2781574 -3.4.24.51 * ophiophagus hannah 70000.0 7 PMID:17337026;PMID:3070833 -3.4.24.52 * protobothrops flavoviridis 60000.0 1 PMID:2398046;PMID:518906 -3.4.24.53 * protobothrops flavoviridis 24000.0 2 PMID:2777746;PMID:4984550 -3.4.24.54 * protobothrops mucrosquamatus 94000.0 1 PMID:6857709 -3.4.24.55 * acinetobacter calcoaceticus 112000.0 4 PMID:1510571;PMID:7738784 -3.4.24.55 * escherichia coli 116000.0 3 PMID:3534791;PMID:7674955;PMID:7680857;PMID:7738784 -3.4.24.55 * halalkalibacterium halodurans 46585.0 2 PMID:15866516 -3.4.24.56 * drosophila melanogaster 110000.0 1 PMID:3139025 -3.4.24.56 * homo sapiens 300000.0 17 PMID:10973971;PMID:11023838;PMID:11368426;PMID:11440853;PMID:15850385;PMID:16574064;PMID:1689296;PMID:16952049;PMID:18226493;PMID:19808678;PMID:23188819;PMID:3059494;PMID:6997171 -3.4.24.56 * mus musculus 118000.0 4 PMID:12732730;PMID:16952049;PMID:24740421 -3.4.24.56 * rattus norvegicus 300000.0 9 PMID:10973971;PMID:11023838;PMID:11368426;PMID:11440853;PMID:1689296;PMID:16952049;PMID:17259336;PMID:3059494;PMID:3888280;PMID:5041199;PMID:7945219 -3.4.24.56 * sus scrofa 135000.0 3 PMID:7009152;PMID:7945219 -3.4.24.56 * xenopus laevis 105000.0 1 PMID:19584300 -3.4.24.57 * mannheimia haemolytica 35000.0 1 PMID:7674959 -3.4.24.58 * daboia russelii 124000.0 4 PMID:1011991;PMID:1629211 -3.4.24.58 * daboia siamensis 93000.0 1 * -3.4.24.58 * protobothrops mucrosquamatus 59000.0 3 * -3.4.24.59 * homo sapiens 78640.0 2 PMID:19900404;PMID:26082885 -3.4.24.59 * rattus norvegicus 75000.0 4 PMID:1322290;PMID:1518864;PMID:22495024;PMID:7674944 -3.4.24.59 * saccharomyces cerevisiae 80000.0 1 * -3.4.24.59 * schizophyllum commune 80000.0 1 * -3.4.24.6 * agkistrodon piscivorus leucostoma 22500.0 2 PMID:1012005 -3.4.24.60 * xenopus laevis 100000.0 3 PMID:1729723 -3.4.24.61 * mus musculus 130000.0 3 PMID:12054470;PMID:12590613 -3.4.24.61 * rattus norvegicus 300000.0 10 PMID:15809022;PMID:2900027;PMID:3897221;PMID:7674957;PMID:8294457;PMID:9685993 -3.4.24.62 * bos taurus 65000.0 4 PMID:2659078;PMID:2825769 -3.4.24.62 * homo sapiens 65000.0 2 PMID:7931007 -3.4.24.63 * danio rerio 73000.0 4 PMID:17516848 -3.4.24.63 * homo sapiens 148000.0 3 PMID:22988105;PMID:26256061 -3.4.24.63 * mus musculus 90000.0 1 PMID:1894622 -3.4.24.63 * rattus norvegicus 171000.0 7 PMID:12399461;PMID:7510289 -3.4.24.64 * arabidopsis thaliana 29000.0 2 PMID:23727204 -3.4.24.64 * bos taurus 70000.0 1 PMID:3531192 -3.4.24.64 * giardia duodenalis 44500.0 1 PMID:19096520 -3.4.24.64 * neurospora crassa 59060.0 4 PMID:2141023;PMID:2967109 -3.4.24.64 * rattus norvegicus 108000.0 7 PMID:1672532;PMID:2236012;PMID:3511913;PMID:3531192;PMID:8132665 -3.4.24.64 * saccharomyces cerevisiae 100000.0 12 PMID:2007593;PMID:2229072;PMID:23563972;PMID:2905264;PMID:3044780;PMID:3061808 -3.4.24.64 * thermus thermophilus 47000.0 2 PMID:19241474 -3.4.24.64 * trypanosoma brucei 50000.0 1 PMID:23563972;PMID:2905264;PMID:3044780 -3.4.24.65 * homo sapiens 54000.0 8 PMID:11575929;PMID:19236151;PMID:19605697;PMID:20127415;PMID:8226919 -3.4.24.65 * mus musculus 59000.0 8 PMID:15885886;PMID:17057219;PMID:17395890;PMID:19346698;PMID:7030312 -3.4.24.65 * rattus norvegicus 54000.0 2 PMID:17268073 -3.4.24.66 * oryzias latipes 25500.0 2 PMID:1397682;PMID:2656665 -3.4.24.67 * fundulus heteroclitus 24000.0 1 PMID:16128802 -3.4.24.67 * oryzias latipes 24000.0 7 PMID:1397682;PMID:15039566;PMID:2656664 -3.4.24.67 * paralichthys olivaceus 34800.0 1 PMID:20035476 -3.4.24.67 * sebastes schlegelii 23075.0 5 PMID:18430023 -3.4.24.68 * clostridium tetani 150700.0 7 PMID:10049679;PMID:12581644;PMID:19602728;PMID:25895970;PMID:27064869;PMID:28645943;PMID:7674951 -3.4.24.69 * clostridium baratii 150000.0 1 PMID:10839626;PMID:11086224;PMID:14561084;PMID:20452328;PMID:32274579;PMID:36977091 -3.4.24.69 * clostridium botulinum 155000.0 59 PMID:10594894;PMID:10600450;PMID:10839626;PMID:10956050;PMID:11086224;PMID:12482605;PMID:14561084;PMID:15517984;PMID:17200883;PMID:18077455;PMID:18400760;PMID:18457419;PMID:20093370;PMID:20452328;PMID:21515732;PMID:2160960;PMID:2185020;PMID:2204031;PMID:2216736;PMID:22367089;PMID:23523511;PMID:23625059;PMID:23656526;PMID:23815186;PMID:24096023;PMID:24568862;PMID:25239905;PMID:28770820;PMID:28898517;PMID:29030733;PMID:29751611;PMID:30355669;PMID:30681794;PMID:32274579;PMID:33837264;PMID:36977091;PMID:4030755;PMID:9717738 -3.4.24.69 * clostridium butyricum 150000.0 1 PMID:10839626;PMID:11086224;PMID:14561084;PMID:20452328;PMID:32274579;PMID:36977091 -3.4.24.7 * homo sapiens 53000.0 4 PMID:1669436;PMID:22524676;PMID:3009463;PMID:4057 -3.4.24.70 * escherichia coli 77100.0 1 PMID:16098472 -3.4.24.70 * salmonella enterica subsp. enterica serovar typhimurium 77000.0 1 * -3.4.24.71 * bos taurus 140000.0 3 PMID:8062389;PMID:9654154 -3.4.24.71 * homo sapiens 300000.0 7 PMID:18992253;PMID:23816989;PMID:25268585;PMID:9409753;PMID:9808768 -3.4.24.71 * rattus norvegicus 190000.0 4 PMID:8034569;PMID:8407980 -3.4.24.72 * agkistrodon contortrix 60000.0 6 PMID:15578961;PMID:15882884 -3.4.24.72 * agkistrodon contortrix contortrix 60000.0 9 PMID:17482478;PMID:1898066;PMID:21479991;PMID:22069611;PMID:7725320 -3.4.24.72 * bacillus subtilis 60000.0 3 * -3.4.24.72 * bothrops neuwiedi 22520.0 1 PMID:15882884 -3.4.24.72 * brevibacillus brevis 56043.0 2 PMID:24735708 -3.4.24.72 * gloydius halys 22710.0 1 PMID:15882884 -3.4.24.72 * neurospora sitophila 34000.0 1 * -3.4.24.72 * patiria pectinifera 48000.0 1 PMID:24977934 -3.4.24.72 * stenotrophomonas maltophilia 47000.0 1 * -3.4.24.72 * streptomyces radiopugnans 38000.0 1 PMID:30871149 -3.4.24.72 * urechis unicinctus 20800.0 1 PMID:23515896 -3.4.24.73 * bothrops jararaca 52000.0 13 PMID:11468397;PMID:1385408;PMID:15313443;PMID:15530968;PMID:15922770;PMID:16564063;PMID:16626772;PMID:17055999;PMID:20851711;PMID:3810664;PMID:8866618 -3.4.24.74 * bacteroides fragilis 44400.0 15 PMID:10456956;PMID:1548060;PMID:16988234;PMID:18462582;PMID:21233422;PMID:23954621;PMID:24145028;PMID:9119484 -3.4.24.75 * salasvirus phi29 40900.0 3 PMID:19361422 -3.4.24.75 * staphylococcus capitis 48000.0 3 PMID:9023202 -3.4.24.75 * staphylococcus simulans 68000.0 18 PMID:16181789;PMID:18721148;PMID:19032148;PMID:24623634;PMID:25136599;PMID:3547405;PMID:36810983;PMID:9106216 -3.4.24.75 * staphylococcus simulans bv. staphylolyticus 27800.0 1 PMID:5456157 -3.4.24.76 * elizabethkingia meningoseptica 40090.0 4 PMID:7771796 -3.4.24.77 * streptomyces caespitosus 15000.0 1 * -3.4.24.77 * streptomyces lividans 23000.0 1 * -3.4.24.77 * streptomyces malaysiensis 35000.0 1 PMID:15639229;PMID:16170526 -3.4.24.77 * streptomyces rimosus 16000.0 2 PMID:16521041 -3.4.24.77 * streptomyces septatus 40000.0 3 PMID:15639229;PMID:16170526 -3.4.24.77 * streptomyces sp. c5 16000.0 1 * -3.4.24.78 * clostridium perfringens 60000.0 6 PMID:11371539 -3.4.24.78 * priestia megaterium 40000.0 1 * -3.4.24.79 * bos taurus 400000.0 1 PMID:12538602 -3.4.24.79 * homo sapiens 400000.0 2 PMID:10077652;PMID:10207505 -3.4.24.80 * homo sapiens 570000.0 42 PMID:10910727;PMID:11171051;PMID:11335709;PMID:11448964;PMID:11911461;PMID:12004057;PMID:12706853;PMID:14670950;PMID:14729674;PMID:15247230;PMID:15381157;PMID:15560752;PMID:15561768;PMID:16971509;PMID:17650075;PMID:19208838;PMID:20587521;PMID:21288898;PMID:22315223;PMID:22843853;PMID:23548172;PMID:24165131;PMID:24637763;PMID:24867951;PMID:24986796;PMID:26091717;PMID:8621565;PMID:9422744 -3.4.24.80 * macaca fascicularis 57000.0 1 PMID:19208838 -3.4.24.80 * mus musculus 70000.0 2 PMID:19208838;PMID:20587521 -3.4.24.80 * rattus norvegicus 57000.0 1 PMID:19208838 -3.4.24.80 * sus scrofa 60000.0 1 PMID:18165051 -3.4.24.81 * bos taurus 64000.0 1 PMID:11481247 -3.4.24.81 * homo sapiens 100000.0 13 PMID:12080182;PMID:14734484;PMID:15341532;PMID:18339644;PMID:18381078;PMID:19159013;PMID:19183255 -3.4.24.81 * mus musculus 60000.0 1 PMID:16624814 -3.4.24.82 * bos taurus 98000.0 4 PMID:10356395;PMID:15161923;PMID:16289022 -3.4.24.82 * homo sapiens 75000.0 12 PMID:10986281;PMID:12202483;PMID:14701864;PMID:16003758;PMID:16099106;PMID:16427204;PMID:17009305;PMID:17311924;PMID:17430884 -3.4.24.82 * rattus norvegicus 68000.0 1 PMID:22420304 -3.4.24.82 * sus scrofa 70000.0 4 PMID:14662755 -3.4.24.83 * bacillus anthracis 710000.0 7 PMID:16797097;PMID:17617379;PMID:17974567;PMID:21121613;PMID:22069624;PMID:22219086 -3.4.24.84 * arabidopsis thaliana 48455.0 1 PMID:12039957 -3.4.24.84 * homo sapiens 54000.0 1 PMID:15479156 -3.4.24.84 * saccharomyces cerevisiae 52300.0 1 PMID:9015299 -3.4.24.84 * schistosoma japonicum 54770.0 1 PMID:31542424 -3.4.24.85 * escherichia coli 45000.0 1 PMID:21810987 -3.4.24.86 * chlorocebus aethiops 160000.0 3 * -3.4.24.86 * homo sapiens 120000.0 4 PMID:16459338 -3.4.24.86 * mus musculus 120000.0 10 PMID:10093737;PMID:11536196;PMID:17264149 -3.4.24.87 * homo sapiens 300000.0 12 PMID:11535495;PMID:16428330;PMID:16706987;PMID:16899464;PMID:19234142;PMID:19574655;PMID:19644711;PMID:20624874;PMID:21715306;PMID:8639781 -3.4.24.87 * rattus norvegicus 195000.0 1 PMID:16689760 -3.4.25.1 * bos taurus 650000.0 1 PMID:1587832 -3.4.25.1 * candida albicans 64000.0 1 PMID:10700377 -3.4.25.1 * ceratitis capitata 26400.0 1 PMID:18163525 -3.4.25.1 * chionodraco hamatus 2000000.0 1 PMID:28757562 -3.4.25.1 * dicentrarchus labrax 2000000.0 1 PMID:28757562 -3.4.25.1 * drosophila melanogaster 894000.0 18 PMID:10893261 -3.4.25.1 * methanosarcina thermophila 690000.0 6 PMID:26005366;PMID:9515917;PMID:9575337 -3.4.25.1 * mus musculus 750000.0 1 PMID:31351175 -3.4.25.1 * patiria pectinifera 700000.0 1 PMID:25760083 -3.4.25.1 * rhodococcus sp. (in: high g+c gram-positive bacteria) 690000.0 5 PMID:7583123 -3.4.25.1 * solanum lycopersicum 550000.0 1 PMID:17952456 -3.4.25.1 * spinacia oleracea 850000.0 1 PMID:1400479 -3.4.25.1 * struthio camelus 700000.0 2 PMID:12437115;PMID:26047503;PMID:9363639 -3.4.25.1 * thermoplasma acidophilum 700000.0 3 PMID:25760083;PMID:9515917;PMID:9575337 -3.4.25.1 * tritrichomonas foetus 700000.0 1 PMID:12437115;PMID:26047503 -3.4.25.1 * trypanosoma brucei 630000.0 14 PMID:12600991;PMID:9228559 -3.4.25.2 * escherichia coli 250000.0 6 PMID:23707406;PMID:8244018;PMID:8662828;PMID:8977122 -3.4.25.2 * haemophilus influenzae 230000.0 1 PMID:24469799 -3.4.25.2 * leishmania donovani 190000.0 2 PMID:22370310 -3.5.1.1 * acinetobacter calcoaceticus 130000.0 3 PMID:36564676;PMID:3911011;PMID:4770738;PMID:938683 -3.5.1.1 * acinetobacter glutaminasificans 130000.0 2 PMID:3911011;PMID:4583638 -3.5.1.1 * anoxybacillus flavithermus 79000.0 1 PMID:26413120;PMID:32097739 -3.5.1.1 * arabidopsis thaliana 27000.0 2 PMID:16705405 -3.5.1.1 * aspergillus oryzae 20800.0 1 PMID:34110268 -3.5.1.1 * azotobacter vinelandii 84000.0 1 PMID:16345199;PMID:3911011 -3.5.1.1 * bacillus licheniformis 134800.0 4 PMID:24905227;PMID:25224912;PMID:36564676;PMID:938683 -3.5.1.1 * bacillus subtilis 155000.0 1 PMID:38004285 -3.5.1.1 * cavia porcellus 138000.0 4 PMID:24669941;PMID:3911011;PMID:4583638 -3.5.1.1 * chlamydomonas sp. 275000.0 1 PMID:3911011 -3.5.1.1 * citrobacter freundii 140000.0 1 PMID:3911011 -3.5.1.1 * cladosporium sp. 120000.0 3 PMID:23180548 -3.5.1.1 * cupriavidus necator 150000.0 1 PMID:4583638 -3.5.1.1 * erwinia aroidea 108000.0 1 PMID:4649741 -3.5.1.1 * escherichia coli 158000.0 8 PMID:15020151;PMID:15477079;PMID:18334484;PMID:32638188;PMID:37949271;PMID:3911011;PMID:4583638 -3.5.1.1 * fusarium tricinctum 171000.0 2 PMID:3911011 -3.5.1.1 * gallus gallus 306000.0 1 PMID:4583638 -3.5.1.1 * geobacillus kaustophilus 145000.0 1 PMID:35863721 -3.5.1.1 * helicobacter pylori 144000.0 7 PMID:11211;PMID:18678946;PMID:18983825;PMID:21048860;PMID:21085483;PMID:25664771;PMID:29079538;PMID:4213333 -3.5.1.1 * heyndrickxia coagulans 85000.0 2 PMID:4583638;PMID:5171719 -3.5.1.1 * homo sapiens 37000.0 3 PMID:24768817 -3.5.1.1 * klebsiella aerogenes 141000.0 1 PMID:3911011 -3.5.1.1 * lathyrus oleraceus 68300.0 1 PMID:3911011 -3.5.1.1 * lupinus angustifolius 75000.0 1 PMID:3911011;PMID:7259189 -3.5.1.1 * lupinus arboreus 75000.0 1 PMID:3911011;PMID:7259189 -3.5.1.1 * lupinus polyphyllus 72000.0 4 PMID:3911011 -3.5.1.1 * luteimicrobium album 110000.0 1 PMID:30274797 -3.5.1.1 * metapseudomonas otitidis 205000.0 2 PMID:26597158;PMID:32052094 -3.5.1.1 * mycobacterium tuberculosis 72000.0 1 PMID:33412160 -3.5.1.1 * neonectria obtusispora 543000.0 2 PMID:2080924 -3.5.1.1 * pectobacterium carotovorum 150000.0 10 PMID:11211;PMID:15032742;PMID:16511054;PMID:20669055;PMID:21048860;PMID:24761390;PMID:25664771;PMID:3911011;PMID:4583638 -3.5.1.1 * phaseolus vulgaris 79000.0 1 PMID:26413120;PMID:32097739 -3.5.1.1 * priestia megaterium 185000.0 2 PMID:30568045 -3.5.1.1 * proteus vulgaris 120000.0 1 PMID:17364689;PMID:3911011 -3.5.1.1 * pseudomonas aeruginosa 160000.0 3 PMID:15469724;PMID:30097831 -3.5.1.1 * pseudomonas chlororaphis subsp. aurantiaca 148000.0 2 * -3.5.1.1 * pseudomonas fluorescens 140000.0 1 PMID:18983825;PMID:29079538 -3.5.1.1 * pseudomonas sp. 122000.0 2 PMID:4583638 -3.5.1.1 * pyrococcus furiosus 75450.0 4 PMID:20370616;PMID:25862541 -3.5.1.1 * rhizobium etli 102000.0 2 PMID:22450783 -3.5.1.1 * rhizomucor miehei 133700.0 3 PMID:24362429 -3.5.1.1 * saccharomyces cerevisiae 800000.0 4 PMID:30836141;PMID:3911011 -3.5.1.1 * serratia marcescens 150000.0 4 PMID:21085483;PMID:3911011;PMID:4213333;PMID:4583638 -3.5.1.1 * sphagnum fallax 126000.0 3 PMID:17364689;PMID:3911011 -3.5.1.1 * staphylococcus sp. 37500.0 1 PMID:24861344 -3.5.1.1 * stenotrophomonas geniculata 135000.0 2 PMID:3911011 -3.5.1.1 * streptomyces gulbargensis 85000.0 1 PMID:24031478 -3.5.1.1 * streptomyces tendae 97400.0 1 PMID:20737924 -3.5.1.1 * stutzerimonas stutzeri 34000.0 2 PMID:7766157 -3.5.1.1 * talaromyces pinophilus 101000.0 1 * -3.5.1.1 * tetrahymena thermophila 1000000.0 4 PMID:8012291 -3.5.1.1 * thermococcus gammatolerans 74000.0 3 * -3.5.1.1 * thermococcus kodakarensis 71000.0 3 PMID:24442710;PMID:31923515 -3.5.1.1 * thermus thermophilus 200000.0 3 PMID:11216870;PMID:17364689 -3.5.1.1 * unidentified proteobacterium 150000.0 2 PMID:22383049 -3.5.1.1 * vibrio cholerae 132000.0 1 PMID:29307802 -3.5.1.1 * vigna unguiculata 70000.0 2 PMID:31923515 -3.5.1.1 * withania somnifera 72000.0 2 PMID:19200159 -3.5.1.1 * wolinella succinogenes 146000.0 2 PMID:11211;PMID:21048860;PMID:25664771;PMID:3911011 -3.5.1.10 * escherichia coli 190000.0 3 PMID:7868604 -3.5.1.100 * delftia tsuruhatensis 50000.0 2 * -3.5.1.100 * pseudomonas sp. 36000.0 3 PMID:15066183 -3.5.1.101 * pseudomonas azotoformans 34000.0 2 PMID:15066172 -3.5.1.102 * methanocaldococcus jannaschii 25000.0 1 PMID:19309161 -3.5.1.103 * mycobacterium tuberculosis 158000.0 9 PMID:16630724 -3.5.1.104 * bacillus subtilis 53000.0 1 PMID:22277649 -3.5.1.105 * klebsiella pneumoniae 64900.0 1 PMID:36002585 -3.5.1.105 * pyrococcus horikoshii 174000.0 3 PMID:16736587;PMID:22713621 -3.5.1.105 * thermococcus kodakarensis 160000.0 2 PMID:15136574 -3.5.1.105 * vibrio alginolyticus 48000.0 2 PMID:16232910 -3.5.1.105 * vibrio parahaemolyticus 46000.0 2 PMID:17334758;PMID:17479220 -3.5.1.106 * pseudomonas putida 29100.0 2 PMID:18678916 -3.5.1.107 * bordetella bronchiseptica 86000.0 2 PMID:22214383 -3.5.1.108 * escherichia coli 34000.0 1 PMID:8530464 -3.5.1.108 * pseudomonas aeruginosa 38600.0 4 PMID:25240855;PMID:9068651 -3.5.1.109 * homo sapiens 43000.0 3 PMID:10970788;PMID:19443184;PMID:33562655 -3.5.1.109 * rattus norvegicus 42000.0 2 PMID:33233706 -3.5.1.11 * achromobacter xylosoxidans 62400.0 2 PMID:15128530 -3.5.1.11 * acinetobacter sp. ap-24 137000.0 1 PMID:26445220 -3.5.1.11 * alcaligenes faecalis 62568.0 4 * -3.5.1.11 * bacillus sp. (in: firmicutes) 40000.0 1 * -3.5.1.11 * bacillus subtilis 148000.0 4 PMID:16511127;PMID:21978958 -3.5.1.11 * escherichia coli 71000.0 11 PMID:19932137;PMID:237220;PMID:9163951 -3.5.1.11 * fusarium sp. 83200.0 1 PMID:8972136 -3.5.1.11 * kluyvera cryocrescens 92000.0 5 PMID:15477078;PMID:15604805;PMID:23908045 -3.5.1.11 * lysinibacillus sphaericus 35000.0 1 PMID:30243389 -3.5.1.11 * pectobacterium atrosepticum 154000.0 1 PMID:25931393 -3.5.1.11 * priestia megaterium 120000.0 13 PMID:10945792;PMID:1367491;PMID:17132166;PMID:237220;PMID:4960153 -3.5.1.11 * providencia rettgeri 65000.0 2 * -3.5.1.11 * pseudomonas melanogenum 146000.0 2 PMID:2165818 -3.5.1.11 * uncultured bacterium 88000.0 3 PMID:24338159 -3.5.1.11 * uncultured gammaproteobacteria bacterium 61900.0 2 * -3.5.1.111 * paenarthrobacter nicotinovorans 137000.0 2 PMID:21288482 -3.5.1.114 * homo sapiens 100000.0 2 PMID:29290764 -3.5.1.114 * mus musculus 140000.0 3 PMID:14656720 -3.5.1.115 * corynebacterium glutamicum 35000.0 1 PMID:25514023 -3.5.1.115 * mycobacterium tuberculosis 33000.0 2 PMID:14556638 -3.5.1.115 * mycolicibacterium smegmatis 36000.0 1 PMID:10978158 -3.5.1.116 * arabidopsis thaliana 200000.0 2 PMID:22493446 -3.5.1.116 * phaseolus vulgaris 300000.0 1 PMID:1910298 -3.5.1.117 * agromyces sp. 27000.0 3 PMID:17827307;PMID:22187439 -3.5.1.117 * arthrobacter sp. 27000.0 2 PMID:24100570 -3.5.1.117 * flavobacterium sp. 31000.0 4 PMID:8285701 -3.5.1.117 * kocuria sp. 27000.0 2 PMID:17827307 -3.5.1.118 * mycolicibacterium smegmatis 24139.0 1 PMID:20420449 -3.5.1.12 * homo sapiens 115000.0 15 PMID:15059618;PMID:2049867;PMID:2201872;PMID:2225462;PMID:3925986;PMID:3949811;PMID:8513569;PMID:9211294 -3.5.1.12 * sus scrofa 115000.0 5 PMID:1679665;PMID:2201872;PMID:2327794;PMID:3949811 -3.5.1.121 * mus musculus 35000.0 1 PMID:8910481 -3.5.1.121 * sus scrofa 34000.0 2 PMID:8089117 -3.5.1.122 * bos taurus 26000.0 1 PMID:19560421 -3.5.1.122 * escherichia coli 40000.0 1 PMID:1898018 -3.5.1.125 * halomonas elongata 36600.0 1 PMID:20849449 -3.5.1.126 * klebsiella pneumoniae subsp. pneumoniae 55000.0 2 PMID:27303801 -3.5.1.13 * aspergillus oryzae 130000.0 1 * -3.5.1.13 * glycine max 63000.0 1 PMID:4473253 -3.5.1.13 * homo sapiens 68000.0 1 PMID:7035166 -3.5.1.13 * lysinibacillus sphaericus 75000.0 1 PMID:4762392 -3.5.1.13 * nocardia farcinica 190000.0 4 PMID:18942140 -3.5.1.13 * paracoccus sp. m1-1 52390.0 3 PMID:22101784 -3.5.1.13 * pseudomonas fluorescens 52500.0 2 PMID:6406224 -3.5.1.13 * starkeya sp. 53000.0 2 PMID:30864436 -3.5.1.13 * streptomyces sp. 31000.0 1 PMID:24752846 -3.5.1.131 * pseudomonas sp. adp 48119.0 1 PMID:29523689 -3.5.1.134 * pantoea agglomerans 55000.0 1 PMID:12226446 -3.5.1.136 * pyrococcus horikoshii 174000.0 1 PMID:22713621 -3.5.1.136 * thermococcus kodakarensis 160000.0 1 PMID:15136574 -3.5.1.137 * achromobacter sp. wm111 170000.0 3 * -3.5.1.137 * aminobacter aminovorans 65000.0 1 PMID:33097501;PMID:8407847 -3.5.1.137 * arthrobacter sp. rc100 100000.0 1 PMID:11445174 -3.5.1.137 * aspergillus niger 48000.0 1 PMID:14612234 -3.5.1.137 * blastobacter sp. m501 166000.0 1 PMID:16348989 -3.5.1.137 * pseudomonas aeruginosa 65000.0 1 PMID:33097501;PMID:8407847 -3.5.1.137 * pseudomonas sp. 50432 88000.0 1 PMID:12149124 -3.5.1.137 * pseudomonas sp. c5pp 70000.0 1 PMID:29079626 -3.5.1.137 * pseudomonas sp. c7 70000.0 1 PMID:29079626 -3.5.1.137 * pseudomonas sp. crl-ok 187000.0 1 PMID:1785941 -3.5.1.137 * rhizobium sp. ac100 160000.0 1 PMID:11872471 -3.5.1.138 * homo sapiens 135000.0 2 PMID:2225462;PMID:3196715 -3.5.1.138 * sus scrofa 140000.0 1 PMID:2317196 -3.5.1.14 * alcaligenes sp. 80000.0 4 PMID:7306559;PMID:7763985;PMID:7764515 -3.5.1.14 * aspergillus oryzae 135000.0 6 PMID:6774495;PMID:7764515;PMID:8149;PMID:9671543 -3.5.1.14 * bacillus sp. (in: firmicutes) 180000.0 7 PMID:8285691 -3.5.1.14 * bos taurus 80000.0 2 PMID:7306559;PMID:7764515 -3.5.1.14 * burkholderia sp. lp5_18b 300000.0 1 PMID:31200632 -3.5.1.14 * deinococcus radiodurans 43000.0 2 PMID:17129628;PMID:17137304 -3.5.1.14 * geobacillus sp. 42000.0 1 * -3.5.1.14 * heliothis virescens 197000.0 2 PMID:22056272 -3.5.1.14 * lactococcus lactis 44147.0 2 PMID:12682714 -3.5.1.14 * mus musculus 140000.0 1 PMID:17012540 -3.5.1.14 * mycobacterium sp. 88000.0 2 PMID:4644302 -3.5.1.14 * paraburkholderia monticola 550000.0 1 PMID:38204129 -3.5.1.14 * pseudomonas sp. 57000.0 2 PMID:9214752 -3.5.1.14 * pseudomonas sp. ak2 380000.0 1 PMID:34176819 -3.5.1.14 * pyrococcus horikoshii 165000.0 2 PMID:11157230;PMID:18248457 -3.5.1.14 * rattus norvegicus 125000.0 6 PMID:14644550;PMID:15796916;PMID:15938642;PMID:8149;PMID:9671543 -3.5.1.14 * stenotrophomonas geniculata 46000.0 1 PMID:32146938 -3.5.1.14 * stenotrophomonas maltophilia 108000.0 2 * -3.5.1.14 * streptomyces mobaraensis 75000.0 5 PMID:16390180;PMID:19734688 -3.5.1.14 * sus scrofa 950000.0 10 PMID:12693939;PMID:18815781;PMID:8149;PMID:9258435;PMID:9671543 -3.5.1.14 * thermococcus litoralis 170000.0 5 PMID:11856837;PMID:12013431 -3.5.1.141 * brucella anthropi 140000.0 3 * -3.5.1.15 * bos taurus 58000.0 1 PMID:1987315 -3.5.1.15 * homo sapiens 73000.0 5 PMID:15851013;PMID:16669630;PMID:17027983;PMID:21095151 -3.5.1.15 * mus musculus 70000.0 3 PMID:10837925;PMID:17254025 -3.5.1.15 * rattus norvegicus 38000.0 2 PMID:16935940 -3.5.1.16 * escherichia coli 170000.0 16 PMID:10684608;PMID:1551850;PMID:16201833;PMID:1628835;PMID:17333302;PMID:22459917 -3.5.1.17 * streptomyces mobaraensis 55816.0 1 PMID:19433221 -3.5.1.18 * enterococcus faecium 43800.0 1 PMID:32860896 -3.5.1.18 * escherichia coli 43500.0 1 PMID:32860896 -3.5.1.18 * haemophilus influenzae 83200.0 10 PMID:16421726;PMID:20138056;PMID:24806882;PMID:29698518;PMID:9671518 -3.5.1.18 * pseudomonas aeruginosa 43500.0 1 PMID:32860896 -3.5.1.18 * salmonella enterica 42000.0 2 PMID:21577314 -3.5.1.18 * staphylococcus aureus 47600.0 1 PMID:32860896 -3.5.1.18 * vibrio cholerae 28700.0 2 PMID:24806882 -3.5.1.19 * acidilobus saccharovorans 44600.0 1 PMID:24512664 -3.5.1.19 * acinetobacter baumannii 47000.0 1 PMID:19859929 -3.5.1.19 * drosophila melanogaster 48000.0 1 PMID:18678867 -3.5.1.19 * escherichia coli 30000.0 1 PMID:3036844;PMID:4399474 -3.5.1.19 * flavobacterium peregrinum 48000.0 1 PMID:4264486;PMID:7374465 -3.5.1.19 * leishmania infantum 24000.0 2 PMID:21819459 -3.5.1.19 * mus musculus 230000.0 3 PMID:7378417 -3.5.1.19 * mycobacterium tuberculosis 39700.0 2 PMID:18201201;PMID:25199451 -3.5.1.19 * mycolicibacterium smegmatis 50000.0 1 PMID:10851013 -3.5.1.19 * oceanobacillus iheyensis 42900.0 2 PMID:23451075 -3.5.1.19 * oryctolagus cuniculus 211000.0 3 PMID:4259917;PMID:4268620 -3.5.1.19 * plasmodium falciparum 50100.0 1 PMID:36009002 -3.5.1.19 * pseudomonas sp. 43000.0 2 * -3.5.1.19 * riemerella anatipestifer 25000.0 1 PMID:27451449 -3.5.1.19 * saccharomyces cerevisiae 34000.0 2 PMID:3036844;PMID:4399474 -3.5.1.19 * streptococcus pneumoniae 21400.0 1 PMID:20853856 -3.5.1.19 * uncultured acidobacteriota bacterium 23900.0 2 PMID:28750065 -3.5.1.19 * unidentified 50300.0 1 PMID:28018295 -3.5.1.2 * acinetobacter glutaminasificans 33000.0 1 PMID:3910999 -3.5.1.2 * alcaligenes faecalis 37000.0 1 * -3.5.1.2 * anabaena sp. 36000.0 2 PMID:19054111 -3.5.1.2 * aspergillus oryzae 49883.0 1 PMID:15555943 -3.5.1.2 * aspergillus sojae 259000.0 3 PMID:23339014 -3.5.1.2 * bacillus amyloliquefaciens 35000.0 1 PMID:19093079 -3.5.1.2 * bacillus cereus 140000.0 2 PMID:23873638 -3.5.1.2 * bacillus licheniformis 39000.0 3 PMID:22433447 -3.5.1.2 * bacillus sp. (in: firmicutes) 66000.0 1 PMID:22367638 -3.5.1.2 * bacillus subtilis 138100.0 4 PMID:18459799 -3.5.1.2 * escherichia coli 148800.0 5 PMID:18459799;PMID:6454 -3.5.1.2 * homo sapiens 65000.0 4 PMID:11163757;PMID:14722097;PMID:19894115 -3.5.1.2 * limosilactobacillus reuteri 70000.0 2 PMID:19784812 -3.5.1.2 * micrococcus luteus 96000.0 13 PMID:10049670;PMID:12595728;PMID:15290324;PMID:16793004;PMID:20050917 -3.5.1.2 * mus musculus 95000.0 3 PMID:10746973;PMID:7663171 -3.5.1.2 * papiliotrema flavescens 270000.0 3 PMID:21737926 -3.5.1.2 * pseudomonas aeruginosa 137000.0 4 PMID:4622222 -3.5.1.2 * pseudomonas chlororaphis subsp. aurantiaca 148000.0 2 * -3.5.1.2 * pseudomonas nitroreducens 93500.0 1 * -3.5.1.2 * pseudomonas sp. 146000.0 3 PMID:4212314;PMID:4650141 -3.5.1.2 * rattus norvegicus 290000.0 14 PMID:12963351;PMID:3830157;PMID:3899104;PMID:4088067;PMID:6743288 -3.5.1.2 * sporosarcina pasteurii 110000.0 2 PMID:11786258 -3.5.1.2 * stenotrophomonas maltophilia 41000.0 2 PMID:16012776 -3.5.1.2 * sus scrofa 64000.0 1 PMID:4088067 -3.5.1.2 * synechocystis sp. pcc 6803 35000.0 1 PMID:19093079 -3.5.1.20 * euglena gracilis 94000.0 2 * -3.5.1.20 * francisella tularensis subsp. tularensis 37000.0 1 * -3.5.1.22 * pseudomonas fluorescens 240000.0 5 PMID:108511;PMID:3128283;PMID:822843 -3.5.1.23 * aspergillus oryzae rib40 97000.0 1 PMID:19650849 -3.5.1.23 * camelus dromedarius 100000.0 2 PMID:23638321 -3.5.1.23 * cavia porcellus 150000.0 2 PMID:7759519 -3.5.1.23 * danio rerio 110000.0 2 PMID:15271994 -3.5.1.23 * drosophila melanogaster 34000.0 1 PMID:20112046 -3.5.1.23 * homo sapiens 150000.0 33 PMID:10563326;PMID:12815059;PMID:17475390;PMID:18619555;PMID:21615386;PMID:22322590;PMID:23707712;PMID:31817238;PMID:32498325;PMID:7744740 -3.5.1.23 * laodelphax striatellus 79300.0 1 PMID:23601004 -3.5.1.23 * mus musculus 135000.0 4 PMID:10652340;PMID:18619555;PMID:19345744 -3.5.1.23 * mycobacterium tuberculosis 71000.0 1 PMID:20139604 -3.5.1.23 * oryza sativa 87000.0 1 PMID:18547394 -3.5.1.23 * pseudomonas aeruginosa 70000.0 2 PMID:10832092;PMID:12821326;PMID:9603946 -3.5.1.23 * rattus norvegicus 133000.0 11 PMID:10488143;PMID:11328816;PMID:15217782;PMID:18430368;PMID:21224012 -3.5.1.24 * bacteroides fragilis 250000.0 2 PMID:10993 -3.5.1.24 * bifidobacterium animalis 140000.0 1 PMID:30098054 -3.5.1.24 * bifidobacterium animalis subsp. lactis 140000.0 2 PMID:21876374 -3.5.1.24 * bifidobacterium bifidum 150000.0 1 PMID:30098054 -3.5.1.24 * bifidobacterium longum 150000.0 7 PMID:15333949;PMID:17454305;PMID:19669939;PMID:25470405;PMID:30098054 -3.5.1.24 * bifidobacterium longum subsp. infantis 35000.0 1 PMID:14762068 -3.5.1.24 * bifidobacterium longum subsp. longum 130000.0 1 PMID:30098054 -3.5.1.24 * bifidobacterium longum subsp. suis 124000.0 1 PMID:30098054 -3.5.1.24 * bifidobacterium pseudocatenulatum 154000.0 3 PMID:25470405;PMID:30098054 -3.5.1.24 * brevibacillus sp. 56000.0 4 PMID:19142574;PMID:19669939 -3.5.1.24 * clostridium perfringens 147000.0 1 PMID:30098054 -3.5.1.24 * enterococcus faecalis 140000.0 1 PMID:17454305;PMID:30098054 -3.5.1.24 * lactiplantibacillus plantarum 150000.0 7 PMID:19669939;PMID:22416715 -3.5.1.24 * lactobacillus acidophilus 126000.0 2 PMID:10194664;PMID:25526498 -3.5.1.24 * lactobacillus johnsonii 115000.0 11 PMID:1429446;PMID:30098054 -3.5.1.24 * ligilactobacillus salivarius 142000.0 6 PMID:17454305;PMID:30098054 -3.5.1.24 * limosilactobacillus fermentum 36500.0 2 PMID:23673477 -3.5.1.24 * limosilactobacillus reuteri 80000.0 1 PMID:30098054 -3.5.1.25 * alteromonas sp. 164000.0 2 PMID:10804240 -3.5.1.25 * escherichia coli 180000.0 3 PMID:17567047;PMID:9143339 -3.5.1.25 * rattus norvegicus 345000.0 1 PMID:3674404 -3.5.1.25 * staphylococcus aureus 86700.0 3 PMID:30411345 -3.5.1.25 * streptococcus pneumoniae 45498.0 2 PMID:24173645 -3.5.1.25 * vibrio cholerae serotype o1 190000.0 2 PMID:8987551 -3.5.1.26 * asobara tabida 84000.0 7 PMID:20036741 -3.5.1.26 * elizabethkingia meningoseptica 38000.0 3 PMID:8250923 -3.5.1.26 * gallus gallus 101000.0 1 PMID:5778645 -3.5.1.26 * homo sapiens 780000.0 20 PMID:1281977;PMID:14616088;PMID:1554372;PMID:1859849;PMID:2005122;PMID:2039475;PMID:666738;PMID:6885799 -3.5.1.26 * spodoptera frugiperda 101000.0 6 PMID:8877373 -3.5.1.26 * sus scrofa 70000.0 1 PMID:5010303 -3.5.1.28 * achromobacter lyticus 19396.0 1 PMID:10833271 -3.5.1.28 * bacillus cereus 31130.0 1 PMID:22344637 -3.5.1.28 * bacillus cereus phage 35000.0 1 PMID:22524239 -3.5.1.28 * bacillus subtilis 220000.0 7 PMID:6150066;PMID:7601853;PMID:803507;PMID:821918 -3.5.1.28 * bacillus thuringiensis 24500.0 1 PMID:23603740 -3.5.1.28 * citrobacter freundii 20847.0 1 PMID:14507260 -3.5.1.28 * clostridium perfringens 40000.0 2 * -3.5.1.28 * escherichia coli 41000.0 4 PMID:1102308;PMID:19237650;PMID:2857097;PMID:6133749 -3.5.1.28 * escherichia phage t7 21000.0 2 PMID:330158 -3.5.1.28 * homo sapiens 135000.0 10 PMID:1974148;PMID:6152147;PMID:7663175;PMID:8605233;PMID:9242559 -3.5.1.28 * latilactobacillus sakei 75000.0 1 PMID:33740141 -3.5.1.28 * lederbergia lenta 58000.0 1 * -3.5.1.28 * mycobacterium phage tm4 60000.0 1 PMID:34906734 -3.5.1.28 * pneumococcal bacteriophage hb-3 36000.0 1 PMID:1967150 -3.5.1.28 * priestia megaterium 21000.0 2 PMID:4626719 -3.5.1.28 * pseudomonas aeruginosa 26000.0 1 PMID:9436306 -3.5.1.28 * staphylococcus aureus 1000000.0 3 PMID:16262792;PMID:5086664 -3.5.1.28 * staphylococcus epidermidis 148000.0 1 PMID:14523110 -3.5.1.28 * staphylococcus lugdunensis 65000.0 1 PMID:19025571 -3.5.1.28 * streptococcus milleri 28000.0 1 PMID:10618198 -3.5.1.28 * streptococcus mitis 36919.0 2 PMID:15576771 -3.5.1.28 * streptococcus pneumoniae 37500.0 4 PMID:12139941;PMID:1355082;PMID:19468224;PMID:6472 -3.5.1.28 * streptomyces globisporus 18500.0 1 * -3.5.1.28 * vibrio anguillarum 62920.0 1 * -3.5.1.29 * mesorhizobium japonicum maff 303099 34000.0 1 PMID:18635903;PMID:19652351 -3.5.1.29 * mesorhizobium loti 64000.0 3 PMID:18635903;PMID:19652351 -3.5.1.29 * pseudomonas sp. 32500.0 1 PMID:3972793 -3.5.1.3 * arabidopsis thaliana 40300.0 2 PMID:24461228 -3.5.1.3 * bacillus subtilis 120000.0 1 PMID:4631109 -3.5.1.3 * homo sapiens 62000.0 2 PMID:19595734 -3.5.1.3 * rattus norvegicus 60000.0 10 PMID:19464248;PMID:19595734;PMID:3003502;PMID:319948;PMID:5114531 -3.5.1.3 * thermus aquaticus 38500.0 1 PMID:4631109 -3.5.1.30 * pseudomonas putida 67000.0 1 PMID:5432799 -3.5.1.32 * campylobacter jejuni 193000.0 2 PMID:16303789 -3.5.1.32 * pseudomonas putida 170000.0 2 * -3.5.1.33 * cyclobacterium marinum 70630.0 1 PMID:38141024 -3.5.1.33 * pyrococcus horikoshii 174000.0 3 PMID:16736587;PMID:22713621 -3.5.1.33 * streptococcus pneumoniae 52700.0 1 PMID:10781617 -3.5.1.33 * thermococcus kodakarensis 160000.0 2 PMID:15136574 -3.5.1.36 * pseudomonas sp. 90000.0 1 PMID:5470822 -3.5.1.38 * acinetobacter glutaminasificans 138000.0 2 PMID:4636333 -3.5.1.38 * citrobacter freundii 140000.0 2 PMID:401650 -3.5.1.38 * delftia acidovorans 156000.0 2 PMID:845119 -3.5.1.38 * pseudomonas sp. 140000.0 2 PMID:956189 -3.5.1.38 * rhodotorula toruloides 180000.0 2 * -3.5.1.39 * ovis aries aries 250000.0 1 PMID:5141674 -3.5.1.4 * aeribacillus pallidus 228000.0 6 PMID:17329817;PMID:17347819;PMID:17442671;PMID:23096998 -3.5.1.4 * alcaligenes sp. 39420.0 1 PMID:15060035 -3.5.1.4 * arthrobacter sp. 40000.0 1 * -3.5.1.4 * blastobacter sp. 48000.0 2 PMID:10788365 -3.5.1.4 * brevibacterium sp. 180000.0 2 PMID:7944367 -3.5.1.4 * burkholderia sp. 186000.0 2 * -3.5.1.4 * delftia acidovorans 59100.0 5 PMID:237757 -3.5.1.4 * escherichia coli 110000.0 3 PMID:3426369;PMID:7916690 -3.5.1.4 * geobacillus subterraneus 111000.0 2 PMID:23708550 -3.5.1.4 * helicobacter pylori 49000.0 1 PMID:9364923 -3.5.1.4 * klebsiella pneumoniae 62000.0 1 PMID:8636044 -3.5.1.4 * methylophilus methylotrophus 155000.0 2 * -3.5.1.4 * microbacterium hydrocarbonoxydans 40000.0 8 PMID:25341397 -3.5.1.4 * nesterenkonia sp. 27950.0 1 PMID:21498772 -3.5.1.4 * paracoccus sp. (in: a-proteobacteria) 52000.0 1 PMID:22101784 -3.5.1.4 * pseudomonas aeruginosa 240000.0 27 PMID:10359655;PMID:110589;PMID:11434308;PMID:17329817;PMID:17347819;PMID:17442671;PMID:2517478;PMID:3108029;PMID:4633800;PMID:7944367 -3.5.1.4 * pseudomonas chlororaphis 105000.0 2 PMID:16534982 -3.5.1.4 * pseudomonas putida 128000.0 4 * -3.5.1.4 * pseudomonas sp. 43000.0 2 PMID:7944367 -3.5.1.4 * pseudonocardia thermophila 108000.0 2 PMID:15103424 -3.5.1.4 * pyrococcus yayanosii 70000.0 2 PMID:24430467 -3.5.1.4 * rhodococcus erythropolis 480000.0 3 PMID:8655547 -3.5.1.4 * rhodococcus rhodochrous 54630.0 1 PMID:7916690 -3.5.1.4 * rhodococcus sp. (in: high g+c gram-positive bacteria) 360000.0 4 PMID:1938876;PMID:7944367 -3.5.1.4 * saccharolobus solfataricus 400000.0 7 PMID:11453462;PMID:16243781;PMID:19478917 -3.5.1.4 * streptococcus phage ej-1 36540.0 1 PMID:12070331 -3.5.1.4 * streptomyces sp. 31000.0 1 PMID:24752846 -3.5.1.4 * sulfurisphaera tokodaii 47000.0 1 PMID:16125409 -3.5.1.4 * xinfangfangia sp. dly26 52000.0 1 PMID:33811594 -3.5.1.40 * fusarium anguioides 65000.0 1 PMID:50318 -3.5.1.41 * absidia caerulea 75000.0 1 PMID:7608108 -3.5.1.41 * amylomyces rouxii 80000.0 1 PMID:20161969 -3.5.1.41 * aspergillus nidulans 27500.0 3 PMID:20161969;PMID:7765883 -3.5.1.41 * bombyx mori 41400.0 3 PMID:24473143 -3.5.1.41 * choristoneura fumiferana 62000.0 2 PMID:23628857 -3.5.1.41 * colletotrichum lindemuthianum 250000.0 9 PMID:12775215;PMID:15555935;PMID:20161969;PMID:7592838;PMID:8987657 -3.5.1.41 * encephalitozoon cuniculi 55000.0 2 PMID:15927751 -3.5.1.41 * entamoeba invadens 34264.0 3 PMID:16621070 -3.5.1.41 * flammulina velutipes 31520.0 4 PMID:19054103;PMID:20161969 -3.5.1.41 * metarhizium anisopliae 70000.0 3 PMID:20161969 -3.5.1.41 * mortierella sp. 67000.0 4 PMID:20161969;PMID:21597184 -3.5.1.41 * penicillium oxalicum 53000.0 1 * -3.5.1.41 * rhizopus circinans 75000.0 1 PMID:18314348 -3.5.1.41 * rhizopus stolonifer 100000.0 2 PMID:20161969 -3.5.1.41 * saccharomyces cerevisiae 43000.0 1 PMID:11812231 -3.5.1.41 * scopulariopsis brevicaulis 55000.0 1 * -3.5.1.41 * tribolium castaneum 129000.0 10 PMID:18342249 -3.5.1.42 * agrobacterium fabrum 41000.0 1 PMID:28388636 -3.5.1.42 * aspergillus usamii 33000.0 1 * -3.5.1.42 * azotobacter vinelandii 26300.0 1 PMID:4144084 -3.5.1.42 * escherichia coli 43000.0 1 PMID:21953451 -3.5.1.42 * oceanobacillus iheyensis 96100.0 2 PMID:24340054 -3.5.1.42 * salmonella enterica subsp. enterica serovar typhimurium 43000.0 1 PMID:6109709 -3.5.1.42 * shewanella oneidensis 80000.0 2 PMID:21953451 -3.5.1.43 * niallia circulans 90000.0 3 PMID:1012012;PMID:816382 -3.5.1.44 * chryseobacterium cucumeris 20000.0 1 PMID:36016794 -3.5.1.44 * chryseobacterium proteolyticum 34000.0 2 PMID:20195702;PMID:36002753 -3.5.1.44 * niallia circulans 125000.0 4 PMID:1012012;PMID:816382 -3.5.1.46 * flavobacterium sp. 84000.0 2 PMID:7262074;PMID:8515236 -3.5.1.46 * pseudomonas sp. 76000.0 2 PMID:7262074;PMID:8515236 -3.5.1.49 * bacillus cereus 160000.0 3 PMID:21705545 -3.5.1.49 * caldanaerobacter subterraneus subsp. tengcongensis 32000.0 2 PMID:16508105;PMID:22207484 -3.5.1.49 * helicobacter pylori 160000.0 2 PMID:11359566 -3.5.1.49 * lupinus albus 52000.0 2 * -3.5.1.49 * methylophilus methylotrophus 137000.0 4 PMID:8841393 -3.5.1.49 * paracoccidioides brasiliensis 191000.0 5 PMID:15716068;PMID:20002196 -3.5.1.5 * bacterium strain sl100 260000.0 3 PMID:9316997 -3.5.1.5 * bos taurus 135000.0 3 PMID:18137 -3.5.1.5 * brucella suis bv. 1 157000.0 8 PMID:18638408 -3.5.1.5 * cajanus cajan 90000.0 1 PMID:18607103 -3.5.1.5 * canavalia ensiformis 590000.0 6 PMID:19724141;PMID:21893219;PMID:7272835 -3.5.1.5 * corynebacterium ammoniagenes 215000.0 3 * -3.5.1.5 * enterobacter sp. 430000.0 2 PMID:18365149 -3.5.1.5 * glutamicibacter creatinolyticus 270000.0 1 PMID:30374769 -3.5.1.5 * glycine max 480000.0 3 PMID:105010 -3.5.1.5 * haloarcula hispanica 544000.0 1 PMID:14981304 -3.5.1.5 * helicobacter felis 484000.0 3 PMID:1452359 -3.5.1.5 * helicobacter mustelae 484000.0 3 PMID:1452359 -3.5.1.5 * helicobacter pylori 600000.0 18 PMID:1452359;PMID:1857197;PMID:19172056;PMID:19754669;PMID:20075619;PMID:35164122 -3.5.1.5 * klebsiella aerogenes 224000.0 7 PMID:2142939 -3.5.1.5 * lathyrus oleraceus 269000.0 1 PMID:25065975 -3.5.1.5 * ligilactobacillus animalis 350000.0 1 * -3.5.1.5 * ligilactobacillus ruminis 150000.0 1 * -3.5.1.5 * limnospira maxima 232000.0 2 * -3.5.1.5 * limosilactobacillus fermentum 220000.0 1 * -3.5.1.5 * limosilactobacillus reuteri 220000.0 10 * -3.5.1.5 * lysinibacillus sphaericus 185000.0 1 * -3.5.1.5 * methylophilus methylotrophus 190000.0 4 * -3.5.1.5 * momordica charantia 174500.0 1 * -3.5.1.5 * morus alba 175000.0 2 PMID:10703052 -3.5.1.5 * mycobacterium tuberculosis 185000.0 3 PMID:7559354 -3.5.1.5 * pseudarthrobacter oxydans 242000.0 1 * -3.5.1.5 * rhizopus arrhizus 172000.0 1 * -3.5.1.5 * rhodobacter capsulatus 185000.0 2 PMID:7559354 -3.5.1.5 * sporosarcina pasteurii 230000.0 7 PMID:3753142 -3.5.1.5 * staphylococcus leei 480000.0 7 PMID:14766306 -3.5.1.5 * staphylococcus saprophyticus 420000.0 7 PMID:8042901 -3.5.1.5 * staphylococcus xylosus 410000.0 1 PMID:8042901 -3.5.1.5 * streptococcus mitior 200000.0 1 * -3.5.1.5 * streptococcus salivarius 140000.0 1 * -3.5.1.5 * ureaplasma urealyticum 380000.0 8 PMID:3690418;PMID:3730958 -3.5.1.5 * vicia sativa 55000.0 1 PMID:38185304 -3.5.1.5 * yersinia enterocolitica 545000.0 1 PMID:20017936 -3.5.1.51 * pseudomonas sp. 275000.0 2 PMID:6788773 -3.5.1.52 * aspergillus tubingensis 43000.0 1 PMID:9312552 -3.5.1.52 * caenorhabditis elegans 110000.0 1 PMID:17522090 -3.5.1.52 * canavalia ensiformis 69000.0 1 * -3.5.1.52 * drosophila melanogaster 74000.0 1 PMID:20479940 -3.5.1.52 * elizabethkingia meningoseptica 35500.0 2 PMID:2182635;PMID:3110550 -3.5.1.52 * lathyrus oleraceus 79500.0 1 PMID:2434326 -3.5.1.52 * mus musculus 212000.0 2 PMID:7535137;PMID:8021270 -3.5.1.52 * oryza sativa 80000.0 1 PMID:10617595 -3.5.1.52 * oryzias latipes 150000.0 1 PMID:10460830 -3.5.1.52 * prunus amygdalus var. dulcis 73000.0 4 PMID:7535137;PMID:9523720 -3.5.1.52 * saccharomyces cerevisiae 43208.0 1 PMID:15610852 -3.5.1.52 * solanum lycopersicum 65800.0 2 PMID:19819901 -3.5.1.52 * terriglobus roseus 70000.0 1 PMID:25294009 -3.5.1.53 * arabidopsis thaliana 279000.0 1 PMID:12435743 -3.5.1.53 * pseudomonas aeruginosa 230000.0 2 PMID:12634339 -3.5.1.53 * selenomonas ruminantium 80000.0 5 PMID:18256468 -3.5.1.53 * zea mays 125000.0 1 * -3.5.1.54 * chlamydomonas reinhardtii 110000.0 2 * -3.5.1.54 * enterobacter cloacae 144000.0 3 PMID:16597948 -3.5.1.54 * granulibacter bethesdensis 65000.0 1 PMID:23282241 -3.5.1.54 * kluyveromyces lactis 400000.0 1 PMID:29263142 -3.5.1.54 * oleomonas sagaranensis 138000.0 2 PMID:15796980 -3.5.1.54 * pseudomonas sp. 360000.0 4 PMID:15901697;PMID:24598916 -3.5.1.54 * saccharomyces cerevisiae 204000.0 1 PMID:6124544 -3.5.1.55 * brevundimonas diminuta 300000.0 4 PMID:6501258;PMID:7096313 -3.5.1.55 * penicillium sp. 192000.0 1 * -3.5.1.56 * alcaligenes sp. 180000.0 3 * -3.5.1.56 * methylobacterium sp. dm1 200000.0 1 PMID:30952664 -3.5.1.56 * paracoccus sp. ssg05 400000.0 2 PMID:32452120 -3.5.1.56 * pseudomonas sp. 250000.0 3 PMID:3732281 -3.5.1.57 * cutaneotrichosporon cutaneum 270000.0 2 * -3.5.1.58 * enterococcus faecalis 220000.0 1 * -3.5.1.59 * arthrobacter sp. 120000.0 2 PMID:1381445 -3.5.1.59 * pseudomonas putida 102000.0 4 PMID:3745168 -3.5.1.6 * agrobacterium tumefaciens 90000.0 2 PMID:19011069;PMID:8055933 -3.5.1.6 * arabidopsis sp. 400000.0 5 PMID:11161056 -3.5.1.6 * arabidopsis thaliana 45500.0 1 PMID:18261476 -3.5.1.6 * bos taurus 40000.0 1 PMID:18261476 -3.5.1.6 * caenorhabditis elegans 472000.0 2 PMID:20840592 -3.5.1.6 * euglena gracilis 2000000.0 1 PMID:115499 -3.5.1.6 * homo sapiens 43160.0 2 PMID:10542323;PMID:22525402 -3.5.1.6 * lachancea kluyveri 50000.0 1 PMID:18261476 -3.5.1.6 * pseudomonas putida 95000.0 3 PMID:18261476;PMID:19011069;PMID:8055933 -3.5.1.6 * rattus norvegicus 42000.0 4 PMID:10989448;PMID:18261476 -3.5.1.6 * rattus rattus 340000.0 9 PMID:10415095;PMID:10542323;PMID:3108250;PMID:3678231;PMID:6433973;PMID:8055933 -3.5.1.6 * zea mays 440000.0 2 PMID:11161056;PMID:18261476 -3.5.1.60 * homo sapiens 45000.0 6 PMID:22040171 -3.5.1.62 * micrococcus luteus 115000.0 1 * -3.5.1.63 * [candida] boidinii 143000.0 3 * -3.5.1.64 * soil bacterium 116000.0 2 * -3.5.1.66 * arthrobacter sp. 205000.0 2 PMID:3972793 -3.5.1.67 * arachis hypogaea 73000.0 3 PMID:6863306 -3.5.1.68 * pseudomonas putida 52000.0 2 PMID:3308850 -3.5.1.68 * rattus norvegicus 420000.0 3 PMID:7612651 -3.5.1.69 * pseudomonas sp. 52000.0 1 PMID:7592649 -3.5.1.69 * shewanella algae 109800.0 2 PMID:11827965 -3.5.1.70 * actinoplanes utahensis 87000.0 7 PMID:1398088;PMID:2760018 -3.5.1.71 * hordeum vulgare 155000.0 1 * -3.5.1.72 * bacillus cereus 66000.0 1 PMID:3142860 -3.5.1.72 * bacillus subtilis 66000.0 1 PMID:3142860 -3.5.1.73 * bacteria 125000.0 2 PMID:7764422 -3.5.1.74 * phocaeicola vulgatus 140000.0 2 PMID:2628421 -3.5.1.75 * bacillus licheniformis 160000.0 2 PMID:7951136 -3.5.1.75 * candida parapsilosis 240000.0 1 PMID:32253090 -3.5.1.75 * prescottella equi 55000.0 1 PMID:16041575 -3.5.1.75 * talaromyces variabilis 96000.0 2 PMID:24078254 -3.5.1.76 * pseudomonas putida 150000.0 3 PMID:1396711 -3.5.1.77 * agrobacterium sp. 84000.0 3 PMID:9648217 -3.5.1.77 * agrobacterium tumefaciens 67000.0 4 PMID:10089472;PMID:8621596 -3.5.1.77 * blastobacter sp. 120000.0 2 PMID:7765578 -3.5.1.77 * comamonas sp. 117000.0 3 PMID:8462543 -3.5.1.77 * ensifer adhaerens 150000.0 3 PMID:16546310 -3.5.1.78 * escherichia coli 170000.0 4 PMID:23097746;PMID:7775463 -3.5.1.79 * xanthobacter agilis 49900.0 3 * -3.5.1.81 * achromobacter denitrificans 58000.0 2 PMID:1368943;PMID:16347618;PMID:23369306;PMID:7763986 -3.5.1.81 * achromobacter xylosoxidans 58000.0 6 PMID:1368943;PMID:16347618;PMID:21546325;PMID:699212;PMID:7763986;PMID:8541651 -3.5.1.81 * alcaligenes faecalis 55000.0 1 PMID:16348465 -3.5.1.81 * defluvibacter sp. 56000.0 1 * -3.5.1.81 * microbacterium natoriense 56000.0 1 PMID:22721690 -3.5.1.81 * pseudomonas sp. 100000.0 2 PMID:699212;PMID:7419468;PMID:8541651 -3.5.1.81 * trichoderma sp. 55000.0 1 PMID:16348465 -3.5.1.82 * achromobacter xylosoxidans 59000.0 2 PMID:8537313 -3.5.1.82 * pseudomonas sp. 59000.0 4 PMID:1768127;PMID:1894006;PMID:7549100 -3.5.1.83 * achromobacter xylosoxidans 56000.0 3 PMID:7763985 -3.5.1.84 * rhizobium leguminosarum bv. viciae 27121.0 1 * -3.5.1.85 * prescottella equi 94000.0 2 * -3.5.1.86 * pseudomonas putida 54000.0 7 PMID:12670968;PMID:15196015 -3.5.1.87 * achromobacter xylosoxidans 134000.0 2 PMID:8590654 -3.5.1.87 * brevibacillus reuszeri 132000.0 2 PMID:23586522 -3.5.1.87 * geobacillus kaustophilus 44000.0 1 PMID:20075610 -3.5.1.87 * geobacillus stearothermophilus 90000.0 3 PMID:19052368 -3.5.1.87 * paenarthrobacter aurescens 93000.0 2 PMID:10194852 -3.5.1.87 * pseudomonas sp. 170000.0 5 PMID:15300419;PMID:22350333;PMID:8829526 -3.5.1.87 * pseudomonas sp. on4a 170000.0 3 PMID:19830420 -3.5.1.87 * siminovitchia fordii 44000.0 1 PMID:20075610 -3.5.1.87 * sinorhizobium meliloti 90000.0 3 PMID:16254442;PMID:16519985 -3.5.1.88 * arabidopsis thaliana 40000.0 2 PMID:16192279;PMID:20936344 -3.5.1.88 * bacillus cereus 17480.0 1 PMID:16508119 -3.5.1.88 * borreliella burgdorferi 60000.0 2 PMID:17977509 -3.5.1.88 * escherichia coli 22000.0 6 PMID:19191548;PMID:23357810;PMID:9374870;PMID:9610360;PMID:9712848 -3.5.1.88 * helicobacter pylori 20973.0 2 PMID:15194508 -3.5.1.88 * homo sapiens 46100.0 3 PMID:21603885;PMID:23815882;PMID:24531459 -3.5.1.88 * leptospira interrogans 43400.0 2 PMID:12127977 -3.5.1.88 * mycobacterium tuberculosis 31000.0 4 PMID:15896710;PMID:16291698;PMID:21507054 -3.5.1.88 * staphylococcus aureus 20000.0 1 PMID:21603885;PMID:23815882 -3.5.1.88 * staphylococcus epidermidis 21800.0 1 PMID:20656778 -3.5.1.89 * entamoeba histolytica 66000.0 2 PMID:16299336;PMID:21118807 -3.5.1.9 * bacillus anthracis 80000.0 2 PMID:24942958 -3.5.1.9 * bos taurus 59000.0 2 PMID:1714804;PMID:50862;PMID:92861 -3.5.1.9 * burkholderia cenocepacia 80000.0 2 PMID:24942958 -3.5.1.9 * cyberlindnera fabianii 54000.0 1 PMID:92861 -3.5.1.9 * cyberlindnera jadinii 56000.0 1 PMID:92861 -3.5.1.9 * drosophila melanogaster 60000.0 3 PMID:50862;PMID:83140 -3.5.1.9 * drosophila virilis 60000.0 2 PMID:50862;PMID:83140 -3.5.1.9 * gallus gallus 60000.0 4 PMID:4135584;PMID:50862;PMID:92861 -3.5.1.9 * lithobates pipiens 30500.0 1 PMID:50862 -3.5.1.9 * meyerozyma guilliermondii 59000.0 3 PMID:50862;PMID:92861 -3.5.1.9 * mus musculus 36000.0 2 PMID:15935693;PMID:50862 -3.5.1.9 * musca domestica 60000.0 1 PMID:50862;PMID:83140 -3.5.1.9 * ogataea henricii 56000.0 2 PMID:92861 -3.5.1.9 * oncorhynchus mykiss 31700.0 1 PMID:1714804 -3.5.1.9 * pseudomonas aeruginosa 80000.0 2 PMID:24942958 -3.5.1.9 * rattus sp. 35500.0 3 PMID:4140137;PMID:84781 -3.5.1.9 * rhodotorula mucilaginosa 59000.0 2 PMID:50862;PMID:92861 -3.5.1.9 * rhodotorula sphaerocarpa 58000.0 2 PMID:92861 -3.5.1.9 * rhodotorula toruloides 58000.0 4 PMID:92861 -3.5.1.9 * saccharomyces cerevisiae 58500.0 2 PMID:50862;PMID:92861 -3.5.1.9 * streptomyces parvulus 43000.0 2 PMID:2425918;PMID:2439878 -3.5.1.9 * yarrowia lipolytica 54000.0 2 PMID:92861 -3.5.1.90 * methanopyrus kandleri 39000.0 1 PMID:16740929 -3.5.1.91 * arthrobacter pascens 121000.0 4 PMID:15358859;PMID:15721791 -3.5.1.92 * equus caballus 55000.0 1 PMID:440106 -3.5.1.92 * homo sapiens 54000.0 1 PMID:20018163 -3.5.1.92 * mus musculus 58000.0 1 PMID:10567687 -3.5.1.92 * sus scrofa 72000.0 5 PMID:10567687;PMID:3517567;PMID:6885768 -3.5.1.93 * brevibacillus laterosporus 70000.0 3 PMID:16809100 -3.5.1.93 * brevundimonas diminuta 84000.0 6 PMID:16809100 -3.5.1.93 * micrococcus luteus 80000.0 1 PMID:20677902 -3.5.1.93 * pseudomonas nitroreducens 58000.0 6 PMID:16809100;PMID:9756463 -3.5.1.93 * pseudomonas sp. 89000.0 16 PMID:1358202;PMID:16809100;PMID:18586517;PMID:21968249;PMID:8031081 -3.5.1.93 * pseudomonas sp. se83 58000.0 2 * -3.5.1.94 * escherichia coli k-12 57000.0 2 PMID:16499623 -3.5.1.97 * acidovorax sp. mr-s7 84000.0 1 PMID:28455333 -3.5.1.97 * delftia sp. vm4 82000.0 1 PMID:26384328 -3.5.1.97 * komagataeibacter europaeus 61000.0 1 PMID:34112823 -3.5.1.97 * pseudoalteromonas maricaloris 91000.0 1 PMID:28920855 -3.5.1.97 * pseudomonas aeruginosa 90000.0 3 PMID:16461666;PMID:21372094 -3.5.1.97 * pseudomonas syringae 600000.0 4 PMID:18997027 -3.5.1.97 * ralstonia pseudosolanacearum gmi1000 88650.0 2 PMID:19426552 -3.5.1.98 * aspergillus nidulans 600000.0 4 PMID:12853613 -3.5.1.98 * babesia bovis 77200.0 2 PMID:22818786 -3.5.1.98 * caenorhabditis elegans 90000.0 1 PMID:12054517 -3.5.1.98 * gallus gallus 400000.0 6 PMID:10231548 -3.5.1.98 * homo sapiens 600000.0 12 PMID:10206986;PMID:10748112;PMID:10926844;PMID:11726666;PMID:11948178;PMID:19410558;PMID:20102703;PMID:21422596;PMID:29948514 -3.5.1.98 * plasmodium falciparum 51000.0 1 PMID:19317450 -3.5.1.98 * pseudomonas aeruginosa 154000.0 1 PMID:27951649 -3.5.1.98 * saccharomyces cerevisiae 110000.0 2 PMID:27665728;PMID:35623387 -3.5.1.98 * thermus caldophilus 42188.0 1 PMID:17632079 -3.5.1.98 * zea mays 500000.0 3 PMID:10677216 -3.5.1.99 * homo sapiens 63000.0 1 PMID:21930339 -3.5.1.99 * mus musculus 63000.0 1 PMID:21930339 -3.5.1.99 * rattus norvegicus 63000.0 1 PMID:21930339 -3.5.2.1 * rhodococcus erythropolis 172000.0 2 PMID:11748240 -3.5.2.10 * alcaligenes sp. 160000.0 1 * -3.5.2.10 * paenarthrobacter ureafaciens 240000.0 1 PMID:4826701 -3.5.2.10 * pseudomonas putida 224000.0 7 PMID:12136154;PMID:500580 -3.5.2.10 * pseudomonas sp. 28440.0 1 PMID:7670196 -3.5.2.11 * papiliotrema laurentii 185000.0 1 PMID:26602 -3.5.2.12 * achromobacter guttatus 110000.0 2 PMID:923591 -3.5.2.12 * flavobacterium sp. 110000.0 1 PMID:923591 -3.5.2.12 * rhodococcus sp. u-224 79500.0 2 PMID:18685217 -3.5.2.13 * thermoplasma acidophilum 30600.0 1 PMID:18309272 -3.5.2.14 * pseudomonas putida 300000.0 3 * -3.5.2.15 * cupriavidus basilensis 204000.0 4 * -3.5.2.15 * pseudomonas sp. 185000.0 3 PMID:10427042 -3.5.2.16 * blastobacter sp. a17p-4 105000.0 2 PMID:9030755 -3.5.2.16 * pseudomonas putida 141000.0 4 PMID:17534563;PMID:21505257 -3.5.2.16 * rattus norvegicus 230000.0 2 PMID:8388376 -3.5.2.16 * sus scrofa 300000.0 2 PMID:10873544 -3.5.2.17 * arabidopsis thaliana 137000.0 2 PMID:20167108 -3.5.2.17 * glycine max 68000.0 3 PMID:10567345;PMID:12481089 -3.5.2.17 * herbaspirillum seropedicae 15000.0 2 PMID:19632197 -3.5.2.17 * oncorhynchus mykiss 40000.0 2 PMID:23994290 -3.5.2.17 * salmonella enterica subsp. enterica serovar dublin 52000.0 2 PMID:16787778 -3.5.2.18 * eubacterium barkeri 178000.0 3 PMID:16894175;PMID:18805424 -3.5.2.19 * streptomyces noursei 50000.0 1 PMID:16641084 -3.5.2.2 * agrobacterium tumefaciens 60000.0 2 PMID:15599462;PMID:16920364;PMID:18556813 -3.5.2.2 * arthrobacter sp. 200000.0 1 * -3.5.2.2 * bacillus sp. (in: firmicutes) 210000.0 2 PMID:15733920;PMID:16284925 -3.5.2.2 * bos taurus 226000.0 3 PMID:486503;PMID:6433973;PMID:6639068 -3.5.2.2 * brevibacillus agri 57000.0 1 * -3.5.2.2 * burkholderia cepacia 52000.0 1 * -3.5.2.2 * corynebacterium pseudodiphtheriticum 160000.0 1 * -3.5.2.2 * crystallibacter crystallopoietes 257000.0 5 PMID:3101721 -3.5.2.2 * dictyostelium discoideum 58200.0 1 PMID:16511257 -3.5.2.2 * geobacillus stearothermophilus 360000.0 16 PMID:10788392;PMID:15304782;PMID:17124633;PMID:17142902;PMID:7765480;PMID:9170256 -3.5.2.2 * geobacillus thermocatenulatus 360000.0 4 PMID:10788392;PMID:15304782;PMID:3101721 -3.5.2.2 * lachancea kluyveri 62300.0 2 PMID:16511040;PMID:37180040 -3.5.2.2 * microbacterium maritypicum 49880.0 1 PMID:16116274 -3.5.2.2 * niallia circulans 212000.0 3 PMID:9170254 -3.5.2.2 * paenarthrobacter aurescens 247000.0 5 PMID:9650283 -3.5.2.2 * pseudomonas fluorescens 235000.0 4 PMID:15304782;PMID:26821258;PMID:3101721 -3.5.2.2 * pseudomonas putida 232000.0 14 PMID:16920364;PMID:17124633;PMID:18556813;PMID:9170256;PMID:9434154;PMID:9928097 -3.5.2.2 * ralstonia pickettii 110000.0 4 PMID:12837777 -3.5.2.2 * rattus norvegicus 266000.0 4 PMID:486503;PMID:6433973;PMID:6639068;PMID:8307005;PMID:8494893 -3.5.2.2 * serratia liquefaciens 207000.0 1 * -3.5.2.2 * siminovitchia fordii 52000.0 1 PMID:20075610 -3.5.2.2 * sinorhizobium meliloti 200000.0 1 PMID:17142902;PMID:7765480 -3.5.2.2 * sus scrofa 210000.0 2 PMID:8307005;PMID:8494893 -3.5.2.2 * thermus sp. 113000.0 4 PMID:10681055 -3.5.2.3 * [bacillus] caldolyticus 48090.0 4 PMID:16819826 -3.5.2.3 * aquifex aeolicus 386000.0 3 PMID:15381710 -3.5.2.3 * betapolyomavirus macacae 43700.0 1 PMID:2871022 -3.5.2.3 * cricetinae 220000.0 3 PMID:6112226;PMID:8099439 -3.5.2.3 * crithidia fasciculata 44000.0 3 PMID:1976382 -3.5.2.3 * deinococcus radiophilus 500000.0 3 PMID:16395552 -3.5.2.3 * escherichia coli 80900.0 2 PMID:2871020;PMID:6142052 -3.5.2.3 * faecalicatena orotica 110000.0 3 PMID:2864918;PMID:8424 -3.5.2.3 * homo sapiens 80000.0 1 PMID:30315107 -3.5.2.3 * klebsiella pneumoniae 80000.0 2 PMID:20676924 -3.5.2.3 * plasmodium berghei 40000.0 2 PMID:18082626;PMID:1976382 -3.5.2.3 * plasmodium falciparum 42000.0 3 PMID:18082626;PMID:1976382 -3.5.2.3 * pseudomonas putida 82000.0 2 PMID:8572888 -3.5.2.3 * rattus norvegicus 870000.0 2 PMID:29209 -3.5.2.3 * saccharomyces cerevisiae 170000.0 5 PMID:34885830 -3.5.2.3 * staphylococcus aureus 60700.0 3 PMID:23246866 -3.5.2.3 * toxoplasma gondii 45600.0 3 PMID:16621066 -3.5.2.5 * aquarana catesbeiana 53300.0 3 PMID:11791734;PMID:8163532 -3.5.2.5 * bacillus licheniformis 215000.0 2 PMID:24333989;PMID:25372819 -3.5.2.5 * cajanus cajan 125000.0 1 * -3.5.2.5 * ctenocephalides felis 53000.0 1 PMID:14871617 -3.5.2.5 * escherichia coli 189500.0 3 PMID:21739308 -3.5.2.5 * glycine max 50000.0 1 * -3.5.2.5 * lithobates pipiens 54000.0 2 PMID:3081517 -3.5.2.5 * phaseolus vulgaris 53000.0 4 PMID:18251875 -3.5.2.5 * pseudomonas aeruginosa 150000.0 2 PMID:6814497 -3.5.2.5 * pseudomonas fluorescens 140000.0 1 PMID:18550550 -3.5.2.6 * [haemophilus] ducreyi 30000.0 1 PMID:11570857 -3.5.2.6 * achromobacter xylosoxidans 27000.0 1 PMID:18362192 -3.5.2.6 * acidovorax sp. mr-s7 84000.0 1 PMID:28455333 -3.5.2.6 * acinetobacter baumannii 35500.0 1 PMID:15649299 -3.5.2.6 * acinetobacter baylyi 40000.0 1 PMID:17403709;PMID:18781358;PMID:6799477;PMID:6970744;PMID:70426 -3.5.2.6 * acinetobacter pittii 40000.0 1 PMID:15047547 -3.5.2.6 * aeromonas hydrophila 25250.0 3 PMID:18498253 -3.5.2.6 * aeromonas sobria 34000.0 2 PMID:18281307;PMID:8998985;PMID:9182099 -3.5.2.6 * aliivibrio fischeri 29000.0 1 PMID:14741712;PMID:15596133;PMID:16553870 -3.5.2.6 * bacillus cereus 115000.0 6 PMID:166286;PMID:4219278;PMID:6414514;PMID:8181949 -3.5.2.6 * bacillus licheniformis 33000.0 4 PMID:6471;PMID:9280280 -3.5.2.6 * bacillus sp. (in: firmicutes) 40000.0 4 * -3.5.2.6 * bacteria 42700.0 1 PMID:19255492 -3.5.2.6 * bacteroides fragilis 26000.0 2 PMID:9126607;PMID:9712862 -3.5.2.6 * brachyspira pilosicoli 63000.0 2 PMID:18212108 -3.5.2.6 * chryseobacterium indologenes 25000.0 2 PMID:17470648 -3.5.2.6 * citrobacter freundii 38000.0 1 PMID:6973612 -3.5.2.6 * citrobacter koseri 22000.0 1 * -3.5.2.6 * elizabethkingia meningoseptica 26000.0 1 PMID:18644957 -3.5.2.6 * enterobacter cloacae 49000.0 3 PMID:16189133;PMID:18312599;PMID:4731970 -3.5.2.6 * escherichia coli 50600.0 10 PMID:12493831;PMID:15561863;PMID:1605608;PMID:17207608;PMID:17403709;PMID:18281307;PMID:18781358;PMID:4564055;PMID:6799477;PMID:6970744;PMID:70426;PMID:9182099 -3.5.2.6 * fluoribacter gormanii 29570.0 2 PMID:17157014 -3.5.2.6 * fusobacterium nucleatum 30000.0 3 PMID:16870757 -3.5.2.6 * janthinobacterium lividum 30915.0 1 PMID:15561856 -3.5.2.6 * klebsiella aerogenes 28600.0 2 PMID:18160520;PMID:4731970 -3.5.2.6 * klebsiella pneumoniae 38000.0 3 PMID:14747733;PMID:15561863 -3.5.2.6 * kluyvera ascorbata 28200.0 2 PMID:17196371 -3.5.2.6 * metapseudomonas otitidis 115000.0 3 PMID:25512428 -3.5.2.6 * moraxella catarrhalis 28000.0 1 PMID:1396750 -3.5.2.6 * moraxella nonliquefaciens 28000.0 1 PMID:1396750 -3.5.2.6 * morganella morganii 41000.0 3 PMID:17403709;PMID:18781358;PMID:6799477;PMID:6970744;PMID:6976340;PMID:70426;PMID:9063463 -3.5.2.6 * mycobacterium tuberculosis 30630.0 2 PMID:16870770;PMID:22587688 -3.5.2.6 * neisseria gonorrhoeae 35000.0 1 PMID:16553870;PMID:17061490 -3.5.2.6 * pectobacterium carotovorum 40000.0 2 PMID:18443127 -3.5.2.6 * photobacterium phosphoreum 31198.0 2 PMID:14741712;PMID:15596133;PMID:16553870 -3.5.2.6 * proteus penneri 30000.0 1 PMID:1605608 -3.5.2.6 * pseudomonas aeruginosa 55100.0 11 PMID:11017203;PMID:15155197;PMID:17403709;PMID:18644957;PMID:18781358;PMID:235307;PMID:25356958;PMID:410783;PMID:6799477;PMID:6970744;PMID:70426 -3.5.2.6 * pseudomonas fluorescens 38720.0 1 PMID:18312599 -3.5.2.6 * pseudomonas luteola 28900.0 1 PMID:19884377 -3.5.2.6 * pseudomonas putida 28370.0 2 PMID:18757180 -3.5.2.6 * psychrobacter immobilis 41000.0 2 PMID:18312599;PMID:6976340;PMID:9063463 -3.5.2.6 * serratia fonticola 31080.0 7 PMID:17875998;PMID:9300809 -3.5.2.6 * serratia marcescens 38720.0 1 PMID:18312599 -3.5.2.6 * shouchella clausii 32000.0 1 PMID:17846134 -3.5.2.6 * staphylococcus aureus 30000.0 1 PMID:1605608 -3.5.2.6 * stenotrophomonas maltophilia 28800.0 1 PMID:9559809 -3.5.2.6 * streptomyces cacaoi 40000.0 1 PMID:17403709;PMID:18781358;PMID:6799477;PMID:6970744;PMID:70426 -3.5.2.6 * streptomyces sp. 20000.0 1 PMID:309466 -3.5.2.6 * sulfurisphaera tokodaii 34000.0 1 PMID:20544975 -3.5.2.6 * yersinia enterocolitica 35000.0 3 PMID:14741712;PMID:15596133;PMID:16553870;PMID:17061490 -3.5.2.6 * yersinia frederiksenii 37000.0 2 PMID:17407578 -3.5.2.6 * yersinia intermedia 37000.0 2 PMID:17407578 -3.5.2.9 * bos taurus 150000.0 1 PMID:14993790 -3.5.2.9 * paecilomyces variotii 260000.0 2 PMID:10460889;PMID:20402795;PMID:9516961 -3.5.2.9 * pseudomonas putida 750000.0 9 PMID:6145710;PMID:8943290 -3.5.2.9 * rattus norvegicus 460000.0 10 PMID:10460889;PMID:1181280;PMID:16660609;PMID:20402795;PMID:239948;PMID:3911006;PMID:7096358;PMID:8943290;PMID:9516961 -3.5.2.9 * saccharomyces cerevisiae 280000.0 2 PMID:10460889;PMID:20402795;PMID:9516961 -3.5.3.1 * [bacillus] caldovelox 195000.0 1 PMID:25447142 -3.5.3.1 * bacillus brevis nagano 180000.0 2 PMID:9244379 -3.5.3.1 * bacillus brevis tt02-8 143000.0 2 PMID:7765033 -3.5.3.1 * bacillus subtilis 49000.0 1 PMID:23625224 -3.5.3.1 * bison bison 118000.0 2 PMID:27468469 -3.5.3.1 * bos taurus 120000.0 3 PMID:16094464;PMID:5023576;PMID:818079 -3.5.3.1 * camelus dromedarius 180000.0 1 PMID:29180053 -3.5.3.1 * coriandrum sativum 160000.0 1 PMID:29944940 -3.5.3.1 * eidolon helvum 86000.0 4 * -3.5.3.1 * equus caballus 138000.0 1 PMID:13328133 -3.5.3.1 * evernia prunastri 330000.0 2 PMID:16663950 -3.5.3.1 * geobacillus thermodenitrificans 192000.0 1 PMID:25908562 -3.5.3.1 * glaciozyma antarctica 34000.0 1 PMID:38300354 -3.5.3.1 * glycine hispida 138000.0 1 PMID:1541268;PMID:4801830 -3.5.3.1 * glycine max 240000.0 2 PMID:16667583 -3.5.3.1 * helicobacter pylori 40000.0 1 PMID:15128304 -3.5.3.1 * heteropneustes fossilis 96000.0 2 PMID:23195132 -3.5.3.1 * homo sapiens 120000.0 14 PMID:17212779;PMID:17562323;PMID:18957279;PMID:19374748;PMID:21945700;PMID:2241902;PMID:240702;PMID:29487337;PMID:743206 -3.5.3.1 * iris x hollandica 191000.0 2 PMID:7140765 -3.5.3.1 * leishmania donovani 108000.0 2 PMID:30831225;PMID:38990998 -3.5.3.1 * mus musculus 38000.0 1 PMID:17071735 -3.5.3.1 * neurospora crassa 266000.0 2 PMID:2953715 -3.5.3.1 * oryctolagus cuniculus 110000.0 2 PMID:4621975 -3.5.3.1 * penicillium chrysogenum 37000.0 1 PMID:25322968 -3.5.3.1 * pista pacifica 34000.0 1 PMID:4462743 -3.5.3.1 * priestia megaterium 34900.0 1 PMID:37466752 -3.5.3.1 * pseudomonas aeruginosa 36000.0 1 PMID:30831225;PMID:38990998 -3.5.3.1 * rattus norvegicus 120000.0 4 PMID:11278703;PMID:16094464;PMID:4355767;PMID:818079 -3.5.3.1 * rhodobacter capsulatus 138000.0 4 PMID:1541268;PMID:4801830 -3.5.3.1 * saccharomyces cerevisiae 37000.0 1 PMID:2404017 -3.5.3.1 * schistosoma mansoni 240000.0 2 PMID:18723022 -3.5.3.1 * solanum lycopersicum 37000.0 2 PMID:15322128 -3.5.3.1 * sulfobacillus acidophilus 197000.0 1 PMID:32529376 -3.5.3.1 * vigna catjang 210000.0 2 PMID:16094464 -3.5.3.10 * arthrobacter sp. 232000.0 2 PMID:12761196 -3.5.3.11 * anabaena sp. 65700.0 1 PMID:25209059 -3.5.3.11 * escherichia coli 80000.0 3 PMID:2153656;PMID:3081491 -3.5.3.11 * evernia prunastri 320000.0 1 * -3.5.3.11 * homo sapiens 120000.0 1 PMID:17212779 -3.5.3.11 * methanocaldococcus jannaschii 190000.0 2 PMID:22439800 -3.5.3.11 * pyrococcus horikoshii 145000.0 2 PMID:15752699 -3.5.3.12 * arabidopsis thaliana 81000.0 2 PMID:12782327 -3.5.3.12 * cucumis sativus 150000.0 8 PMID:12821325 -3.5.3.12 * enterococcus faecalis 82000.0 2 PMID:17028272 -3.5.3.12 * glycine max 70000.0 1 PMID:1989611 -3.5.3.12 * lathyrus sativus 56000.0 2 PMID:6895223 -3.5.3.12 * listeria monocytogenes 46800.0 1 PMID:23918931 -3.5.3.12 * oryza sativa 183000.0 2 * -3.5.3.12 * pseudomonas aeruginosa 89000.0 4 PMID:11673419;PMID:12634339;PMID:16661738 -3.5.3.12 * pseudomonas aeruginosa pa14 39900.0 1 PMID:20149107 -3.5.3.12 * selenomonas ruminantium 45000.0 2 PMID:18256468 -3.5.3.12 * streptococcus mutans 40000.0 1 PMID:25819331 -3.5.3.12 * zea mays 85000.0 5 PMID:11314948;PMID:12634339;PMID:16661738 -3.5.3.13 * pseudomonas aeruginosa 108000.0 9 PMID:16475788;PMID:5012325 -3.5.3.14 * pseudomonas chlororaphis 300000.0 1 PMID:4651648 -3.5.3.14 * pseudomonas putida 240000.0 2 * -3.5.3.15 * bos taurus 125000.0 2 PMID:6860676 -3.5.3.15 * canis lupus familiaris 75000.0 1 PMID:20668670 -3.5.3.15 * gallus gallus 74500.0 3 PMID:24161753 -3.5.3.15 * giardia duodenalis 85000.0 2 PMID:18697833 -3.5.3.15 * homo sapiens 80000.0 2 PMID:24316829;PMID:39286527 -3.5.3.15 * mus musculus 100000.0 7 PMID:16137333;PMID:1778991;PMID:19830834;PMID:8354274;PMID:9192727 -3.5.3.15 * ovis aries 83000.0 1 PMID:9129218 -3.5.3.15 * porphyromonas gingivalis 60890.0 4 PMID:10377098;PMID:20850413 -3.5.3.15 * rattus norvegicus 76000.0 3 PMID:1778991;PMID:7217033;PMID:9192727 -3.5.3.17 * pseudomonas aeruginosa 215000.0 2 * -3.5.3.18 * bos taurus 31200.0 1 PMID:17600152 -3.5.3.18 * homo sapiens 40000.0 3 PMID:12370443;PMID:17895252;PMID:18171027 -3.5.3.18 * pseudomonas aeruginosa 58000.0 10 PMID:12370443;PMID:15312771;PMID:15865451;PMID:16229464;PMID:16634643 -3.5.3.18 * rattus norvegicus 34000.0 3 PMID:17322279;PMID:2722865 -3.5.3.2 * corynebacterium sp. 150000.0 2 * -3.5.3.2 * flavobacterium sp. 281000.0 2 * -3.5.3.2 * pseudomonas sp. 165000.0 4 * -3.5.3.20 * pseudomonas putida 170000.0 1 * -3.5.3.22 * streptomyces clavuligerus 199500.0 5 PMID:12020346;PMID:7601835;PMID:8088547 -3.5.3.23 * pseudomonas aeruginosa 48874.0 1 PMID:9393691 -3.5.3.24 * thermus thermophilus 32500.0 1 PMID:15983049 -3.5.3.26 * arabidopsis thaliana 200000.0 2 PMID:22493446 -3.5.3.27 * synechocystis sp. pcc 6803 313000.0 1 PMID:31914412 -3.5.3.3 * acinetobacter sp. 100000.0 1 * -3.5.3.3 * actinobacillus sp. 46500.0 2 PMID:11807264;PMID:16701795 -3.5.3.3 * alcaligenes sp. 51000.0 1 PMID:3742654 -3.5.3.3 * glutamicibacter nicotianae 90000.0 3 PMID:25536878 -3.5.3.3 * paracoccus sp. wb1 48000.0 1 * -3.5.3.3 * pseudomonas putida 94000.0 6 PMID:1015832;PMID:10230521;PMID:29090065;PMID:8251936;PMID:8443 -3.5.3.3 * pseudomonas sp. 180000.0 1 * -3.5.3.4 * branchiostoma belcheri tsingtauense 43200.0 1 * -3.5.3.4 * chlamydomonas reinhardtii 200000.0 2 PMID:10860551 -3.5.3.4 * mus musculus 47200.0 2 PMID:10864446 -3.5.3.4 * oryza sativa japonica group 52700.0 1 PMID:38622442 -3.5.3.4 * pseudomonas aeruginosa 154000.0 3 PMID:11452882;PMID:4989534 -3.5.3.4 * saccharomyces cerevisiae 38580.0 1 PMID:15229895 -3.5.3.4 * xenopus laevis 44700.0 2 PMID:10864446 -3.5.3.6 * aspergillus fumigatus 110000.0 1 PMID:25582958 -3.5.3.6 * aspergillus nidulans 120000.0 1 PMID:31615671 -3.5.3.6 * bacillus cereus 46940.0 2 PMID:18366187 -3.5.3.6 * burkholderia mallei 46050.0 2 PMID:18366187 -3.5.3.6 * enterococcus faecium 95600.0 2 PMID:26363115 -3.5.3.6 * escherichia coli 45900.0 2 PMID:18366187 -3.5.3.6 * euglena gracilis 87000.0 2 * -3.5.3.6 * giardia duodenalis 140000.0 6 PMID:18179862;PMID:19640561;PMID:9468500 -3.5.3.6 * halobacterium salinarum 105000.0 2 * -3.5.3.6 * lactococcus lactis ssp. lactis 140000.0 1 PMID:18179862 -3.5.3.6 * lactococcus lactis subsp. lactis 140000.0 2 PMID:17223359 -3.5.3.6 * lentilactobacillus buchneri 199000.0 1 PMID:3139054 -3.5.3.6 * metamycoplasma arthritidis 87300.0 4 PMID:697802;PMID:856796 -3.5.3.6 * metamycoplasma hominis 96000.0 3 PMID:16787144;PMID:18179862;PMID:3806049 -3.5.3.6 * metapseudomonas furukawaii 46000.0 1 PMID:31326652 -3.5.3.6 * mycoplasmopsis arginini 90000.0 2 PMID:10901172;PMID:1568792 -3.5.3.6 * porphyromonas gingivalis 60890.0 4 PMID:19545534 -3.5.3.6 * pseudomonas aeruginosa 184000.0 2 PMID:12454483;PMID:18179862 -3.5.3.6 * pseudomonas plecoglossicida 49000.0 3 PMID:19280262;PMID:26041055;PMID:31062871 -3.5.3.6 * pseudomonas putida 130000.0 5 PMID:1568792;PMID:18179862;PMID:237904;PMID:729806 -3.5.3.6 * streptococcus pyogenes 160000.0 5 PMID:23867361;PMID:26695833;PMID:9632565 -3.5.3.7 * arthrobacter sp. 232000.0 2 PMID:12761196 -3.5.3.7 * aspergillus niger 336000.0 1 PMID:30806615 -3.5.3.7 * brevibacterium helvolum 210000.0 5 * -3.5.3.7 * flavobacterium sp. 240000.0 1 * -3.5.3.7 * iguania 252000.0 1 PMID:5862400 -3.5.3.7 * pseudomonas aeruginosa 140000.0 3 PMID:12029055 -3.5.3.7 * pseudomonas putida 190000.0 2 PMID:5043851 -3.5.3.7 * pseudomonas sp. 186000.0 4 * -3.5.3.7 * tinca tinca 170000.0 2 PMID:1380333 -3.5.3.8 * bacillus subtilis 220000.0 1 PMID:4990470 -3.5.3.8 * pseudomonas putida 50000.0 1 PMID:3308850 -3.5.3.9 * arabidopsis thaliana 103000.0 2 PMID:18065556 -3.5.3.9 * glycine max 100000.0 2 PMID:18065556 -3.5.3.9 * metabacillus fastidiosus 128000.0 2 PMID:7503567 -3.5.3.9 * phaseolus vulgaris 52400.0 4 PMID:15627697;PMID:24460648 -3.5.4.1 * achromobacter denitrificans 200000.0 3 * -3.5.4.1 * arthrobacter sp. 200000.0 2 * -3.5.4.1 * aspergillus fumigatus 32000.0 2 * -3.5.4.1 * aspergillus niger 98000.0 1 PMID:36627557 -3.5.4.1 * chromobacterium violaceum 156000.0 4 * -3.5.4.1 * escherichia coli 300000.0 9 PMID:11812140;PMID:17588533;PMID:8226944;PMID:8450832 -3.5.4.1 * proteus mirabilis 200000.0 1 * -3.5.4.1 * pseudomonas chlororaphis subsp. aureofaciens 630000.0 2 * -3.5.4.1 * pseudomonas putida 260000.0 1 * -3.5.4.1 * saccharomyces cerevisiae 41000.0 4 PMID:19265397;PMID:5126939 -3.5.4.1 * salmonella enterica subsp. enterica serovar typhimurium 230000.0 2 PMID:3000814;PMID:6758859 -3.5.4.1 * serratia marcescens 580000.0 2 * -3.5.4.10 * bacillus subtilis 55746.0 1 PMID:3036807 -3.5.4.10 * escherichia coli 22000.0 1 PMID:29799386 -3.5.4.10 * gallus gallus 71000.0 2 PMID:1937050;PMID:7354066 -3.5.4.10 * homo sapiens 62100.0 1 PMID:7947835 -3.5.4.10 * methanocaldococcus jannaschii 21500.0 1 PMID:11844782 -3.5.4.10 * methanothermobacter thermautotrophicus 22000.0 1 PMID:17407260 -3.5.4.10 * mus musculus 350000.0 2 PMID:241692 -3.5.4.10 * rattus norvegicus 64200.0 1 PMID:9332377 -3.5.4.10 * staphylococcus lugdunensis 106000.0 1 PMID:29063699 -3.5.4.10 * thermotoga maritima 49700.0 1 PMID:18260100 -3.5.4.11 * priestia megaterium 110000.0 1 PMID:34599 -3.5.4.12 * bacillus subtilis 170000.0 1 PMID:418064 -3.5.4.12 * cricetinae 130000.0 2 PMID:4455201 -3.5.4.12 * equus asinus 120000.0 4 PMID:101672;PMID:1898061;PMID:8448179 -3.5.4.12 * escherichia phage t2 124000.0 2 PMID:357901;PMID:4550765;PMID:4621659 -3.5.4.12 * homo sapiens 117000.0 5 PMID:101672;PMID:2247612;PMID:7240207;PMID:8448179 -3.5.4.12 * paramecium bursaria chlorella virus 1 17000.0 1 PMID:17475641 -3.5.4.12 * tequatrovirus t4 127000.0 5 PMID:10777550 -3.5.4.13 * methanocaldococcus jannaschii 23400.0 2 PMID:12670946 -3.5.4.13 * paramecium bursaria chlorella virus 1 17000.0 1 PMID:17475641 -3.5.4.13 * salmonella enterica subsp. enterica serovar typhimurium 82000.0 1 PMID:1324907;PMID:234434;PMID:357902 -3.5.4.15 * arabidopsis thaliana 45000.0 1 PMID:24130159 -3.5.4.15 * camellia sinensis 18000.0 1 * -3.5.4.15 * pseudomonas putida 20000.0 1 * -3.5.4.16 * drosophila melanogaster 575000.0 5 PMID:16966327;PMID:3080426 -3.5.4.16 * escherichia coli 300000.0 5 PMID:12297008;PMID:4296838;PMID:821948 -3.5.4.16 * geobacillus stearothermophilus 105000.0 1 PMID:3891906 -3.5.4.16 * homo sapiens 600000.0 3 * -3.5.4.16 * listeria monocytogenes serotype 1/2a 22000.0 1 PMID:31475925 -3.5.4.16 * methanocaldococcus jannaschii 84000.0 2 PMID:17497938 -3.5.4.16 * mus musculus 362000.0 3 PMID:1905717;PMID:19104007;PMID:19762783 -3.5.4.16 * neisseria gonorrhoeae 135000.0 3 PMID:19767425;PMID:28126741 -3.5.4.16 * nocardia iowensis 35000.0 3 PMID:15135390 -3.5.4.16 * rattus norvegicus 260000.0 3 PMID:15448133;PMID:19104007;PMID:19762783 -3.5.4.16 * serratia indica 200000.0 3 * -3.5.4.16 * solanum lycopersicum 91000.0 2 PMID:12221287 -3.5.4.16 * spinacia oleracea 135000.0 2 PMID:28126741 -3.5.4.16 * streptomyces tubercidicus 230000.0 2 PMID:9868539 -3.5.4.17 * todarodes pacificus 140000.0 2 * -3.5.4.17 * turbo cornutus 140000.0 2 * -3.5.4.19 * methanococcus vannielii 34000.0 3 PMID:9931020 -3.5.4.19 * neurospora crassa 126000.0 1 PMID:4309307 -3.5.4.19 * saccharomyces cerevisiae 190000.0 2 PMID:379004 -3.5.4.2 * blastobotrys adeninivorans 40000.0 1 PMID:23902582 -3.5.4.2 * escherichia coli 120000.0 2 PMID:11440125 -3.5.4.2 * kluyveromyces lactis 46000.0 1 PMID:30555824 -3.5.4.2 * leishmania donovani 40800.0 1 PMID:22238346 -3.5.4.2 * methanocaldococcus jannaschii 80000.0 1 PMID:26990095 -3.5.4.2 * pseudomonas synxantha 37000.0 1 * -3.5.4.2 * saccharomyces cerevisiae 46000.0 3 PMID:18673302 -3.5.4.2 * schizosaccharomyces pombe 48000.0 3 PMID:18673302 -3.5.4.21 * corynebacterium glutamicum 195000.0 2 PMID:15148566 -3.5.4.21 * flavobacterium filamentosum 272500.0 2 PMID:3980459 -3.5.4.21 * pseudomonas putida 77 260000.0 1 * -3.5.4.21 * uncultured bacterium 285000.0 2 PMID:1819465 -3.5.4.22 * pseudomonas putida 275000.0 4 PMID:22833679;PMID:5845838 -3.5.4.23 * aspergillus terreus 55000.0 13 PMID:10833262;PMID:236272;PMID:8159161 -3.5.4.24 * bombyx mori 74000.0 2 * -3.5.4.25 * eremothecium ashbyi 34800.0 1 PMID:20943182 -3.5.4.25 * escherichia coli 44000.0 2 PMID:6990194;PMID:9211333 -3.5.4.25 * meyerozyma guilliermondii 170000.0 1 PMID:3891906 -3.5.4.25 * mycobacterium tuberculosis 90000.0 2 PMID:23999287 -3.5.4.25 * streptomyces coelicolor 46100.0 1 PMID:18281960 -3.5.4.26 * acinetobacter baumannii 58000.0 4 PMID:23722836 -3.5.4.26 * bacillus subtilis 40000.0 1 PMID:9068650 -3.5.4.26 * escherichia coli 80000.0 2 PMID:30756;PMID:9068650 -3.5.4.27 * archaeoglobus fulgidus 80000.0 2 PMID:8481088 -3.5.4.27 * methanocaldococcus jannaschii 34899.0 1 PMID:11265475 -3.5.4.27 * methanopyrus kandleri 42000.0 5 PMID:11265475;PMID:9676239 -3.5.4.27 * methanosarcina barkeri 82000.0 4 PMID:11265475;PMID:2298699;PMID:3782039 -3.5.4.27 * methanothermobacter thermautotrophicus 82000.0 4 PMID:11265475;PMID:2298699;PMID:3782039 -3.5.4.27 * methanothermus fervidus 39000.0 2 PMID:11265475 -3.5.4.27 * methylorubrum extorquens 67000.0 4 PMID:10215859;PMID:11265475 -3.5.4.27 * uncultured archaeon 34982.0 1 PMID:24707918 -3.5.4.28 * methanocaldococcus jannaschii 230000.0 2 PMID:24375099 -3.5.4.28 * streptomyces albus 58300.0 2 PMID:2592350 -3.5.4.29 * methanocaldococcus jannaschii 98300.0 4 PMID:12475257 -3.5.4.3 * blastobotrys adeninivorans 110000.0 3 PMID:24481069 -3.5.4.3 * bos taurus 105000.0 4 PMID:36031;PMID:3966794;PMID:6713831;PMID:7040358 -3.5.4.3 * camellia sinensis 54000.0 1 * -3.5.4.3 * cavia porcellus 120000.0 1 PMID:6713831 -3.5.4.3 * drosophila melanogaster 48000.0 1 PMID:19567870 -3.5.4.3 * escherichia coli 50200.0 1 PMID:10913105 -3.5.4.3 * homo sapiens 240000.0 17 PMID:10075721;PMID:239400;PMID:28777;PMID:36031;PMID:3966794;PMID:546144;PMID:6713831;PMID:7040358 -3.5.4.3 * kluyveromyces lactis 10600.0 1 PMID:30555824 -3.5.4.3 * mus musculus 200000.0 3 PMID:10075721;PMID:28777;PMID:3966794;PMID:6713831;PMID:7040358 -3.5.4.3 * oryctolagus cuniculus 525000.0 24 PMID:10075721;PMID:239400;PMID:28777;PMID:36031;PMID:3966794;PMID:4857982;PMID:6713831;PMID:7040358 -3.5.4.3 * rattus norvegicus 110000.0 5 PMID:36031;PMID:3966794;PMID:4857982;PMID:6713831;PMID:7040358 -3.5.4.3 * sus sp. 240000.0 4 PMID:10075721;PMID:28777;PMID:3966794;PMID:6713831;PMID:7040358 -3.5.4.30 * escherichia coli 20000.0 1 PMID:15539408 -3.5.4.30 * methanocaldococcus jannaschii 77900.0 1 PMID:12909016 -3.5.4.31 * methanocaldococcus jannaschii 230000.0 2 PMID:24375099 -3.5.4.33 * escherichia coli 18718.0 1 PMID:12110595 -3.5.4.33 * saccharomyces cerevisiae 75000.0 1 PMID:8893855 -3.5.4.34 * drosophila melanogaster 45350.0 1 PMID:10629039 -3.5.4.35 * methanopyrus kandleri 60000.0 2 PMID:19407206 -3.5.4.36 * homo sapiens 46000.0 2 PMID:15148397;PMID:15273326 -3.5.4.36 * monodelphis domestica 27000.0 1 PMID:10373583 -3.5.4.36 * oryctolagus cuniculus 28000.0 1 PMID:8063816 -3.5.4.36 * rattus norvegicus 27280.0 3 PMID:8407891;PMID:8511591 -3.5.4.37 * homo sapiens 300000.0 7 PMID:12618436;PMID:17662848;PMID:25272020 -3.5.4.37 * xenopus laevis 120000.0 2 PMID:8144588 -3.5.4.38 * bos taurus 26000.0 3 PMID:19766322 -3.5.4.38 * homo sapiens 184000.0 2 PMID:28981865 -3.5.4.38 * mus musculus 24000.0 1 PMID:10373455 -3.5.4.38 * oryctolagus cuniculus 26000.0 2 PMID:16280388 -3.5.4.39 * methanocaldococcus jannaschii 84000.0 3 PMID:17497938 -3.5.4.4 * arabidopsis thaliana 39950.0 1 PMID:18673302 -3.5.4.4 * argopecten irradians concentricus 130000.0 1 * -3.5.4.4 * azotobacter vinelandii 66000.0 1 PMID:7212927 -3.5.4.4 * bacillus cereus 68000.0 2 PMID:3096380 -3.5.4.4 * bos taurus 41000.0 5 PMID:18774942;PMID:5127384;PMID:9388 -3.5.4.4 * camelus dromedarius 43000.0 1 PMID:12379282 -3.5.4.4 * escherichia coli 29000.0 1 PMID:357905 -3.5.4.4 * fasciola gigantica 29000.0 1 PMID:18436213 -3.5.4.4 * gallus gallus 110000.0 3 PMID:12381379;PMID:14990221 -3.5.4.4 * homo sapiens 298000.0 13 PMID:12381379;PMID:16542154;PMID:18680557;PMID:3606997;PMID:4625871;PMID:4721618;PMID:6947796;PMID:9388 -3.5.4.4 * hyalomma dromedarii 42000.0 1 PMID:17089216 -3.5.4.4 * kitasatospora aureofaciens 163000.0 3 * -3.5.4.4 * klebsiella sp. 26000.0 1 * -3.5.4.4 * methanocaldococcus jannaschii 230000.0 2 PMID:24375099 -3.5.4.4 * micrococcus sodonensis 130000.0 1 PMID:1168529 -3.5.4.4 * mus musculus 40000.0 2 PMID:10718633;PMID:20815357 -3.5.4.4 * nocardioides sp. 80000.0 2 PMID:7986382 -3.5.4.4 * plasmodium yoelii 41000.0 1 PMID:21945268 -3.5.4.4 * pseudomonas iodinum 240000.0 2 PMID:624400 -3.5.4.4 * rattus norvegicus 45000.0 1 PMID:19327339;PMID:6815190 -3.5.4.4 * saccharomyces cerevisiae 39630.0 1 PMID:18673302 -3.5.4.4 * schizosaccharomyces pombe 41200.0 1 PMID:18673302 -3.5.4.4 * streptomyces coelicolor 182000.0 2 PMID:21511036 -3.5.4.4 * streptomyces sp. 90000.0 2 PMID:19327339;PMID:6815190 -3.5.4.4 * sus scrofa 45000.0 2 PMID:19327339;PMID:6815190;PMID:7159417 -3.5.4.4 * xenopus laevis 120000.0 2 PMID:8144588 -3.5.4.41 * methanocaldococcus jannaschii 230000.0 2 PMID:24375099 -3.5.4.42 * pseudomonas sp. 174000.0 4 PMID:12218024;PMID:9422605 -3.5.4.43 * pseudomonas sp. 105000.0 2 PMID:17660279 -3.5.4.44 * halomonas elongata 44900.0 1 PMID:20849449 -3.5.4.5 * [bacillus] caldolyticus 16000.0 4 PMID:11739901;PMID:15713780;PMID:20035876;PMID:20075615 -3.5.4.5 * arabidopsis thaliana 63000.0 6 PMID:10024464;PMID:10469156;PMID:8812871 -3.5.4.5 * bacillus subtilis 56000.0 3 PMID:10493793 -3.5.4.5 * brassica oleracea 20800.0 1 PMID:24475736 -3.5.4.5 * crithidia fasciculata 45000.0 1 PMID:6381719 -3.5.4.5 * escherichia coli 73000.0 13 PMID:10024464;PMID:10493793;PMID:357899;PMID:357900;PMID:3910086;PMID:4202859;PMID:4944311;PMID:6386817;PMID:8204580;PMID:8812871 -3.5.4.5 * gallus gallus 15000.0 1 PMID:10024464 -3.5.4.5 * geobacillus stearothermophilus 16000.0 2 PMID:20035876;PMID:20075615 -3.5.4.5 * haliotis diversicolor supertexta 20000.0 2 PMID:19150626 -3.5.4.5 * homo sapiens 60000.0 9 PMID:11739901;PMID:12353623;PMID:15713780;PMID:1929398;PMID:357899;PMID:6386817;PMID:8812871 -3.5.4.5 * klebsiella pneumoniae subsp. pneumoniae 66000.0 1 PMID:31495495 -3.5.4.5 * mus musculus 74000.0 2 PMID:6386817;PMID:692393 -3.5.4.5 * mycobacterium tuberculosis 55000.0 5 PMID:20035876;PMID:20075615 -3.5.4.5 * nocardioides sp. 52000.0 2 PMID:12353623;PMID:1929398 -3.5.4.5 * saccharomyces cerevisiae 57000.0 1 PMID:357899;PMID:8812871 -3.5.4.5 * sporosarcina psychrophila 15000.0 2 PMID:11739901;PMID:15713780 -3.5.4.5 * trypanosoma brucei brucei 77700.0 1 PMID:31391279 -3.5.4.5 * trypanosoma cruzi 90000.0 1 PMID:6381719 -3.5.4.5 * zea mays 78000.0 1 * -3.5.4.6 * aspergillus oryzae 85390.0 2 PMID:27539573;PMID:27596420 -3.5.4.6 * carassius auratus 160000.0 3 PMID:18931932 -3.5.4.6 * cyprinus carpio 55000.0 1 * -3.5.4.6 * gallus gallus 276000.0 3 PMID:102336;PMID:15094842 -3.5.4.6 * helix pomatia 60000.0 1 PMID:37471401 -3.5.4.6 * homo sapiens 400000.0 9 PMID:12482028;PMID:1627354;PMID:16570231;PMID:18493842;PMID:20207414;PMID:618880;PMID:8343524 -3.5.4.6 * oryctolagus cuniculus 320000.0 6 PMID:11341922;PMID:12535614;PMID:13463019;PMID:17254852 -3.5.4.6 * raja clavata 330000.0 1 * -3.5.4.6 * saccharomyces cerevisiae 83000.0 1 PMID:391808 -3.5.4.9 * aedes aegypti 200000.0 1 * -3.5.4.9 * clostridium formicaceticum 41000.0 2 PMID:3702702;PMID:7061514 -3.5.4.9 * drosophila melanogaster 32000.0 1 PMID:9061797 -3.5.4.9 * escherichia coli 70000.0 5 PMID:1748668;PMID:9061797 -3.5.4.9 * homo sapiens 36700.0 3 PMID:18804703;PMID:29225823 -3.5.4.9 * hordeum vulgare 40000.0 1 * -3.5.4.9 * lathyrus oleraceus 60000.0 4 PMID:22558288;PMID:8304211 -3.5.4.9 * leishmania major 65000.0 1 PMID:22108435 -3.5.4.9 * methanosarcina barkeri 318700.0 2 PMID:15349715 -3.5.4.9 * methylorubrum extorquens 45000.0 2 PMID:10215859 -3.5.4.9 * mus musculus 34000.0 1 PMID:9454603 -3.5.4.9 * neurospora sp. 40000.0 1 * -3.5.4.9 * pseudomonas aeruginosa 60000.0 2 PMID:22558288;PMID:8304211 -3.5.4.9 * saccharomyces cerevisiae 100000.0 1 PMID:9454603 -3.5.4.9 * sus scrofa 218000.0 3 PMID:476523;PMID:838698 -3.5.4.9 * thermoplasma acidophilum dsm 1728 30600.0 1 PMID:18309272 -3.5.4.9 * triticum aestivum 40000.0 1 * -3.5.4.9 * vicia faba 40000.0 1 * -3.5.4.9 * zea mays 40000.0 1 * -3.5.5.1 * acetivibrio thermocellus 33000.0 1 PMID:26629931 -3.5.5.1 * acidovorax facilis 570000.0 3 PMID:17154311;PMID:22441427;PMID:33045860 -3.5.5.1 * acinetobacter sp. 580000.0 1 PMID:14632988;PMID:19040702 -3.5.5.1 * acinetobacter sp. ak226 580000.0 1 PMID:14632988;PMID:19040702 -3.5.5.1 * aeribacillus pallidus 600000.0 6 PMID:14632988;PMID:19040702;PMID:20607233;PMID:33045860 -3.5.5.1 * alcaligenes faecalis 460000.0 6 PMID:14632988;PMID:33045860 -3.5.5.1 * alcaligenes sp. 376000.0 2 PMID:20960011 -3.5.5.1 * alcaligenes sp. ecu0401 376000.0 1 PMID:33045860 -3.5.5.1 * arabidopsis thaliana 450000.0 4 PMID:19040702;PMID:33045860 -3.5.5.1 * arthrobacter sp. 30000.0 2 PMID:16346987 -3.5.5.1 * aspergillus niger 650000.0 8 PMID:14632988;PMID:17061133;PMID:19040702;PMID:21210990;PMID:33045860 -3.5.5.1 * bradyrhizobium japonicum 455000.0 3 PMID:19040702;PMID:33045860 -3.5.5.1 * brassica napus 420000.0 2 PMID:19040702 -3.5.5.1 * comamonas testosteroni 38000.0 1 PMID:14632988 -3.5.5.1 * fusarium oxysporum 550000.0 2 PMID:14632988;PMID:19040702;PMID:33045860 -3.5.5.1 * fusarium oxysporum f. sp. melonis 550000.0 2 PMID:14632988;PMID:19040702;PMID:33045860 -3.5.5.1 * fusarium proliferatum 37000.0 3 PMID:23226336;PMID:25595333 -3.5.5.1 * fusarium solani 620000.0 9 PMID:14632988;PMID:19040702;PMID:23761 -3.5.5.1 * klebsiella pneumoniae 74000.0 1 PMID:14632988;PMID:33045860 -3.5.5.1 * nocardia sp. 560000.0 4 PMID:14632988;PMID:21655 -3.5.5.1 * paenarthrobacter aurescens 520000.0 4 PMID:25742970 -3.5.5.1 * pannonibacter carbonis 31000.0 1 PMID:33045860 -3.5.5.1 * pseudomonas aeruginosa 30000.0 1 PMID:28959330 -3.5.5.1 * pseudomonas fluorescens 138000.0 2 PMID:33045860 -3.5.5.1 * pseudomonas putida 412000.0 3 PMID:33045860 -3.5.5.1 * pseudomonas sp. 41000.0 2 PMID:14632988;PMID:24837382 -3.5.5.1 * pyrococcus abyssi 60000.0 1 PMID:33045860 -3.5.5.1 * pyrococcus sp. m24d13 38500.0 1 PMID:26973832 -3.5.5.1 * pyrococcus sp. mc-fb 60000.0 1 PMID:28744780 -3.5.5.1 * rhodococcus erythropolis 55000.0 1 PMID:24781748 -3.5.5.1 * rhodococcus rhodochrous 650000.0 20 PMID:10601860;PMID:14632988;PMID:17371547;PMID:18412544;PMID:18677653;PMID:19040702;PMID:33045860 -3.5.5.1 * rhodococcus sp. (in: high g+c gram-positive bacteria) 560000.0 6 PMID:1388821;PMID:14632988;PMID:19040702;PMID:33045860 -3.5.5.1 * sorghum bicolor 42000.0 2 PMID:18003897 -3.5.5.1 * uncultured bacterium 38000.0 1 PMID:20725724 -3.5.5.1 * uncultured burkholderiaceae bacterium 38830.0 1 PMID:26868129 -3.5.5.4 * lupinus angustifolius 38000.0 2 PMID:16786295 -3.5.5.4 * pseudomonas sp. 1000000.0 2 * -3.5.5.4 * sorghum bicolor 42000.0 2 PMID:18003897 -3.5.5.5 * alcaligenes faecalis 460000.0 8 PMID:19040702;PMID:21913706;PMID:2269298;PMID:33113984;PMID:37453025 -3.5.5.5 * alcaligenes sp. 520000.0 2 PMID:24712720 -3.5.5.5 * alcaligenes sp. mtcc 10675 520000.0 1 PMID:37453025 -3.5.5.5 * arabidopsis thaliana 450000.0 1 PMID:37453025 -3.5.5.5 * bradyrhizobium japonicum 455000.0 4 PMID:18061298;PMID:37453025 -3.5.5.5 * brassica napus 420000.0 1 PMID:37453025 -3.5.5.5 * burkholderia cenocepacia 450000.0 1 PMID:37453025 -3.5.5.5 * fusarium haematococcum 360000.0 1 PMID:37453025 -3.5.5.5 * luminiphilus syltensis 43000.0 1 PMID:25854992 -3.5.5.5 * pseudomonas fluorescens 130000.0 6 PMID:16272385;PMID:37453025 -3.5.5.5 * pseudomonas oryzihabitans 37000.0 1 PMID:26564406 -3.5.5.5 * pseudomonas putida 412000.0 3 PMID:16341723;PMID:18704770 -3.5.5.5 * trichophyton benhamiae 336000.0 1 PMID:37453025 -3.5.5.6 * klebsiella pneumoniae subsp. ozaenae 74000.0 5 PMID:19040702;PMID:2834373 -3.5.5.7 * acidovorax facilis 570000.0 2 PMID:19040702 -3.5.5.7 * acinetobacter sp. 580000.0 3 PMID:19040702 -3.5.5.7 * bradyrhizobium sp. 36320.0 1 * -3.5.5.7 * cereibacter sphaeroides 560000.0 2 PMID:23900907 -3.5.5.7 * comamonas testosteroni 38000.0 1 PMID:19040702 -3.5.5.7 * fusarium proliferatum 37000.0 1 PMID:25595333 -3.5.5.7 * methylibium petroleiphilum 37970.0 1 * -3.5.5.7 * pannonibacter carbonis 31000.0 1 PMID:30888572 -3.5.5.7 * pseudomonas fluorescens 138000.0 2 PMID:19153727 -3.5.5.7 * pseudomonas sp. 41000.0 1 * -3.5.5.7 * pseudomonas syringae pv. syringae 36550.0 1 * -3.5.5.7 * pyrococcus abyssi 60000.0 6 PMID:16495079;PMID:19040702 -3.5.5.7 * rhodococcus rhodochrous 650000.0 11 PMID:1390687;PMID:18412544;PMID:19040702;PMID:2394676;PMID:33045860 -3.5.5.7 * synechococcus elongatus 36350.0 1 * -3.5.5.7 * synechocystis sp. 390000.0 2 PMID:19040702 -3.5.5.7 * thermotoga maritima 30070.0 1 PMID:26059515 -3.5.5.7 * uncultured bacterium 700000.0 2 PMID:20725724 -3.5.5.8 * alphaproteobacteria 50267.0 2 PMID:24002749 -3.5.5.8 * thiobacillus thioparus 240000.0 7 PMID:1577754;PMID:16879822;PMID:17222425;PMID:9573140 -3.5.5.8 * thiohalophilus thiocyanatoxydans 140000.0 5 PMID:17964868 -3.5.99.10 * arabidopsis thaliana 40000.0 1 PMID:27458092 -3.5.99.10 * capra hircus 41400.0 1 PMID:38801230 -3.5.99.10 * salmo salar 42700.0 2 PMID:32576850 -3.5.99.11 * comamonas testosteroni 30000.0 2 PMID:17259310 -3.5.99.11 * ectopseudomonas oleovorans 100000.0 2 PMID:9573204 -3.5.99.13 * catharanthus roseus 41500.0 6 PMID:1330135;PMID:17719488;PMID:476085;PMID:510306;PMID:7763429 -3.5.99.13 * cinchona robusta 35000.0 2 * -3.5.99.13 * rauvolfia serpentina 35300.0 3 PMID:15450856;PMID:7763429 -3.5.99.13 * rauvolfia verticillata 38200.0 1 * -3.5.99.14 * eschscholtzia tenuifolia 15500.0 1 PMID:17404986 -3.5.99.14 * thalictrum flavum 21180.0 1 PMID:17900926 -3.5.99.14 * thalictrum flavum ssp. glaucum 28000.0 2 PMID:12107162 -3.5.99.16 * alangium lamarckii 30000.0 1 PMID:11065292 -3.5.99.2 * aneurinibacillus aneurinilyticus 100000.0 2 PMID:7044223 -3.5.99.2 * bacillus subtilis 30000.0 1 PMID:25014715 -3.5.99.2 * helicobacter pylori 25643.0 2 PMID:19780837 -3.5.99.2 * staphylococcus aureus 82900.0 3 PMID:19888457;PMID:21206023;PMID:24311574 -3.5.99.5 * burkholderia cepacia 18000.0 1 PMID:16267312 -3.5.99.5 * ectopseudomonas oleovorans 100000.0 2 PMID:9573204 -3.5.99.5 * pseudomonas sp. 67000.0 2 PMID:11081795 -3.5.99.6 * bos taurus 210000.0 2 PMID:9774701 -3.5.99.6 * candida albicans 17500.0 1 * -3.5.99.6 * canis lupus familiaris 180000.0 2 PMID:1497340 -3.5.99.6 * escherichia coli 190000.0 4 PMID:6375729;PMID:8240271 -3.5.99.6 * giardia duodenalis 30700.0 2 PMID:25326378;PMID:9041531 -3.5.99.6 * mus musculus 33000.0 1 PMID:10481053 -3.5.99.6 * musca domestica 154000.0 1 PMID:236465 -3.5.99.6 * staphylococcus aureus 57000.0 2 PMID:30411345 -3.5.99.6 * streptococcus mutans 25500.0 1 PMID:17768362 -3.5.99.6 * thermococcus kodakarensis 71800.0 2 PMID:16199574 -3.5.99.7 * amycolatopsis methanolica 144000.0 1 * -3.5.99.7 * aspergillus luchuensis 49480.0 2 PMID:35103879 -3.5.99.7 * beauveria bassiana 37190.0 1 PMID:35103879 -3.5.99.7 * blastomyces gilchristii 29660.0 1 PMID:35103879 -3.5.99.7 * cadophora sp. dse1049 37510.0 1 PMID:35103879 -3.5.99.7 * cladophialophora carrionii 39300.0 1 PMID:35103879 -3.5.99.7 * coccidioides posadasii 37900.0 1 PMID:35103879 -3.5.99.7 * colletotrichum aenigma 39550.0 2 PMID:35103879 -3.5.99.7 * colletotrichum orbiculare 36220.0 1 PMID:35103879 -3.5.99.7 * colletotrichum siamense 40370.0 4 PMID:35103879 -3.5.99.7 * colletotrichum sidae 33020.0 1 PMID:35103879 -3.5.99.7 * colletotrichum trifolii 36050.0 1 PMID:35103879 -3.5.99.7 * colletotrichum viniferum 39660.0 1 PMID:35103879 -3.5.99.7 * cutaneotrichosporon oleaginosum 36320.0 1 PMID:35103879 -3.5.99.7 * cyberlindnera jadinii 37360.0 1 PMID:35103879 -3.5.99.7 * cyberlindnera saturnus 69000.0 2 PMID:9604000 -3.5.99.7 * fusarium agapanthi 36140.0 1 PMID:35103879 -3.5.99.7 * fusarium beomiforme 36400.0 1 PMID:35103879 -3.5.99.7 * fusarium mundagurra 69160.0 1 PMID:35103879 -3.5.99.7 * fusarium oxysporum f. sp. cubense 35920.0 1 PMID:35103879 -3.5.99.7 * fusarium pseudocircinatum 40980.0 1 PMID:35103879 -3.5.99.7 * fusarium subglutinans 82470.0 1 PMID:35103879 -3.5.99.7 * gloeophyllum trabeum 36600.0 1 PMID:35103879 -3.5.99.7 * heliocybe sulcata 36240.0 1 PMID:35103879 -3.5.99.7 * lachnellula occidentalis 38760.0 1 PMID:35103879 -3.5.99.7 * lachnellula suecica 16180.0 1 PMID:35103879 -3.5.99.7 * lasiodiplodia theobromae 36630.0 1 PMID:35103879 -3.5.99.7 * metarhizium anisopliae 38510.0 1 PMID:35103879 -3.5.99.7 * metarhizium brunneum 38920.0 1 PMID:35103879 -3.5.99.7 * metarhizium robertsii 37060.0 1 PMID:35103879 -3.5.99.7 * methylobacterium nodulans 144000.0 2 PMID:23517598 -3.5.99.7 * methylobacterium radiotolerans 144000.0 2 PMID:23517598 -3.5.99.7 * mycena galopus 37690.0 1 PMID:35103879 -3.5.99.7 * naematelia encephala 37000.0 1 PMID:35103879 -3.5.99.7 * penicillium citrinum 39170.0 1 PMID:35103879 -3.5.99.7 * pseudomonas chlororaphis 36800.0 2 * -3.5.99.7 * pseudomonas putida 105000.0 5 PMID:15588698 -3.5.99.7 * pseudomonas sp. 112000.0 5 * -3.5.99.7 * trichoderma asperellum 37060.0 1 PMID:35103879 -3.5.99.7 * trichoderma guizhouense 36640.0 1 PMID:35103879 -3.5.99.7 * trichoderma parareesei 37870.0 1 PMID:35103879 -3.5.99.7 * trichoderma reesei 38000.0 1 PMID:35103879 -3.6.1.1 * acidithiobacillus thiooxidans 88000.0 2 PMID:14950;PMID:20646294 -3.6.1.1 * anabaena sp. 114000.0 2 PMID:17635582 -3.6.1.1 * aquifex aeolicus 105000.0 1 PMID:11676598 -3.6.1.1 * arabidopsis thaliana 132000.0 6 PMID:21122813;PMID:31371393 -3.6.1.1 * aranda christine 28000.0 1 * -3.6.1.1 * aspergillus oryzae 60800.0 1 PMID:4358816 -3.6.1.1 * bacillus subtilis 36000.0 2 PMID:9633597 -3.6.1.1 * blastochloris viridis 240000.0 2 PMID:17635582 -3.6.1.1 * bos taurus 56000.0 3 PMID:22485177;PMID:6132917;PMID:9143364 -3.6.1.1 * cereibacter sphaeroides 60000.0 1 PMID:4333319 -3.6.1.1 * chlamydomonas reinhardtii 37000.0 6 PMID:16313235 -3.6.1.1 * desulfovibrio desulfuricans 43000.0 2 PMID:5132274 -3.6.1.1 * dunaliella salina 60000.0 1 * -3.6.1.1 * enterococcus faecalis 128000.0 2 PMID:6116703 -3.6.1.1 * enterococcus faecium 70000.0 1 PMID:5018696 -3.6.1.1 * escherichia coli 120000.0 5 PMID:10095764;PMID:22984449;PMID:8530523;PMID:9237692 -3.6.1.1 * gallus gallus 36000.0 1 PMID:25748422 -3.6.1.1 * geobacillus stearothermophilus 122000.0 2 PMID:5398 -3.6.1.1 * gossypium hirsutum 100000.0 1 PMID:4333319;PMID:8003527 -3.6.1.1 * helicobacter pylori 121000.0 6 PMID:10985749;PMID:16239722;PMID:16988955;PMID:17598086 -3.6.1.1 * homo sapiens 42000.0 3 PMID:22485177;PMID:656444 -3.6.1.1 * hypophthalmichthys nobilis 50000.0 2 * -3.6.1.1 * leishmania major 30000.0 2 PMID:14988016 -3.6.1.1 * medicago truncatula 138000.0 1 PMID:31371393 -3.6.1.1 * methanothermobacter thermautotrophicus 100000.0 2 PMID:4333319;PMID:8003527 -3.6.1.1 * methanothrix thermoacetophila 71400.0 2 PMID:22927778;PMID:25268 -3.6.1.1 * mus musculus 32000.0 1 PMID:22485177 -3.6.1.1 * mycoplasma suis 80000.0 3 PMID:1315573;PMID:14950;PMID:20646294 -3.6.1.1 * oryctolagus cuniculus 67000.0 2 PMID:22927778;PMID:25268 -3.6.1.1 * papaver rhoeas 26500.0 2 PMID:17086195 -3.6.1.1 * pseudanabaena sp. 20000.0 1 PMID:17635582 -3.6.1.1 * pyrococcus furiosus 22000.0 2 * -3.6.1.1 * pyrococcus horikoshii 24500.0 2 PMID:16243777 -3.6.1.1 * rattus norvegicus 61000.0 2 PMID:17933215;PMID:6125258 -3.6.1.1 * rhodobacter capsulatus 60000.0 1 PMID:4333319 -3.6.1.1 * rhodopseudomonas palustris 100000.0 4 PMID:3008782;PMID:4333319;PMID:8003527 -3.6.1.1 * rhodospirillum rubrum 100000.0 1 PMID:4333319;PMID:8003527 -3.6.1.1 * rubrivivax gelatinosus 100000.0 1 PMID:4333319;PMID:8003527 -3.6.1.1 * saccharolobus islandicus 19550.0 1 PMID:34781059 -3.6.1.1 * saccharomyces cerevisiae 71000.0 6 PMID:340461;PMID:4602033;PMID:6129562;PMID:765323 -3.6.1.1 * saccharum officinarum 38000.0 1 * -3.6.1.1 * shewanella sp. 34000.0 1 PMID:24397719 -3.6.1.1 * solanum tuberosum 24000.0 1 PMID:8552717 -3.6.1.1 * sorghum bicolor 42000.0 1 PMID:2829731 -3.6.1.1 * spinacia oleracea 55000.0 1 PMID:9328290 -3.6.1.1 * staphylococcus aureus 34000.0 1 PMID:25576794 -3.6.1.1 * streptococcus gordonii 78000.0 3 PMID:16829218;PMID:21450519 -3.6.1.1 * sulfolobus acidocaldarius 80000.0 10 PMID:10049508;PMID:1315573;PMID:1321720;PMID:20646294;PMID:7771779;PMID:8282721;PMID:8922285 -3.6.1.1 * sulfolobus sp. 19435.0 1 PMID:9972267 -3.6.1.1 * sus scrofa 66000.0 4 PMID:22485177;PMID:239696;PMID:6132917;PMID:9143364 -3.6.1.1 * synechocystis sp. 120000.0 2 PMID:1327774;PMID:17635582 -3.6.1.1 * thermococcus onnurineus 120000.0 2 PMID:19286799;PMID:36361526 -3.6.1.1 * thermococcus thioreducens 21000.0 2 PMID:23192028 -3.6.1.1 * thermoplasma acidophilum 110000.0 2 PMID:1327774;PMID:17635582 -3.6.1.1 * thermotoga maritima 29728.0 1 PMID:12657645 -3.6.1.1 * trichinella spiralis 41480.0 1 PMID:33413587 -3.6.1.1 * trypanosoma cruzi 47900.0 2 PMID:24033456 -3.6.1.1 * vigna radiata 81000.0 1 PMID:16018964 -3.6.1.10 * saccharomyces cerevisiae 142000.0 5 PMID:15792812;PMID:21314609;PMID:8900207 -3.6.1.11 * chlorobaculum tepidum 100400.0 4 PMID:24969471 -3.6.1.11 * escherichia coli 100000.0 4 PMID:16678853;PMID:8380170 -3.6.1.11 * homo sapiens 50000.0 1 PMID:18700747 -3.6.1.11 * leishmania major 48000.0 1 PMID:12393865 -3.6.1.11 * microlunatus phosphovorus 93000.0 2 * -3.6.1.11 * mycobacterium tuberculosis 36600.0 1 PMID:22132215 -3.6.1.11 * saccharolobus solfataricus 47900.0 1 PMID:12324325 -3.6.1.11 * saccharomyces cerevisiae 830000.0 24 PMID:15061692;PMID:15170373;PMID:16266267;PMID:16862600;PMID:17009950;PMID:17140377;PMID:17599355;PMID:18976214;PMID:25034634;PMID:8071344;PMID:8157625;PMID:9650588 -3.6.1.11 * tethya aurantium 73000.0 3 PMID:7654762 -3.6.1.11 * trypanosoma brucei 42870.0 2 PMID:21208463 -3.6.1.12 * homo sapiens 20800.0 2 PMID:21671327;PMID:24467396 -3.6.1.12 * mus musculus 19000.0 2 PMID:19220460 -3.6.1.12 * tequatrovirus t4 59000.0 1 PMID:6853543 -3.6.1.13 * arabidopsis thaliana 32000.0 2 PMID:18798872 -3.6.1.13 * artemia sp. 31000.0 1 PMID:8645701 -3.6.1.13 * deinococcus radiodurans 21800.0 1 PMID:19923723 -3.6.1.13 * homo sapiens 85000.0 9 PMID:10567213;PMID:10722730;PMID:11825615;PMID:12427752;PMID:16860484;PMID:9693963 -3.6.1.13 * mus musculus 40000.0 1 PMID:10722730 -3.6.1.13 * rattus norvegicus 47000.0 4 PMID:7819284;PMID:8192656 -3.6.1.13 * synechococcus sp. 166000.0 3 PMID:15158734 -3.6.1.13 * thermus thermophilus 38000.0 1 PMID:14501132 -3.6.1.14 * lupinus luteus 25000.0 1 PMID:9359862 -3.6.1.14 * saccharomyces cerevisiae 45000.0 1 PMID:9565693 -3.6.1.15 * bos taurus 60200.0 2 PMID:18976223 -3.6.1.15 * classical swine fever virus 60000.0 1 PMID:17447110 -3.6.1.15 * homo sapiens 75000.0 2 PMID:17291528;PMID:2156508 -3.6.1.15 * murine norovirus 1200000.0 1 PMID:30265237 -3.6.1.15 * mycolicibacterium smegmatis 78000.0 1 PMID:26953339 -3.6.1.15 * rattus norvegicus 46000.0 2 PMID:2867090;PMID:6087895 -3.6.1.15 * staphylococcus aureus 25000.0 1 PMID:33955674 -3.6.1.15 * streptomyces coelicolor 25000.0 1 PMID:33955674 -3.6.1.15 * west nile virus 60000.0 1 PMID:11238848 -3.6.1.17 * arabidopsis thaliana 21670.0 1 PMID:18345354 -3.6.1.17 * artemia salina 17500.0 1 PMID:181087 -3.6.1.17 * caenorhabditis elegans 19000.0 1 PMID:11738085 -3.6.1.17 * chlorella vulgaris 22000.0 1 PMID:163189;PMID:6321483;PMID:8198532 -3.6.1.17 * homo sapiens 19200.0 2 PMID:1652465;PMID:8381042 -3.6.1.17 * lupinus angustifolius 19120.0 1 PMID:11439089 -3.6.1.17 * lupinus sp. 22980.0 2 PMID:9425114 -3.6.1.17 * mus musculus 19800.0 1 PMID:6286385 -3.6.1.17 * photinus pyralis 16000.0 2 PMID:7876110 -3.6.1.17 * plasmodium falciparum 17000.0 1 PMID:22791172 -3.6.1.17 * rattus norvegicus 22000.0 3 PMID:163189;PMID:181087;PMID:3003092;PMID:6282267;PMID:6321483;PMID:8198532 -3.6.1.17 * saccharomyces cerevisiae 49000.0 2 PMID:8381667 -3.6.1.17 * scenedesmus sp. 26000.0 1 PMID:8198532 -3.6.1.17 * solanum lycopersicum 20000.0 1 PMID:8810090 -3.6.1.18 * homo sapiens 74000.0 3 PMID:9211338 -3.6.1.18 * oryctolagus cuniculus 71000.0 1 * -3.6.1.18 * rattus norvegicus 560000.0 5 PMID:2987256;PMID:5636362;PMID:7691801 -3.6.1.18 * treponema pallidum 36593.0 2 PMID:23447540 -3.6.1.2 * cavia porcellus 130000.0 1 * -3.6.1.21 * escherichia coli 50000.0 2 PMID:11416161 -3.6.1.22 * caenorhabditis elegans 78200.0 2 PMID:10873676 -3.6.1.22 * escherichia coli 60000.0 2 PMID:7829480 -3.6.1.22 * mycobacterium tuberculosis 51000.0 2 PMID:22026918 -3.6.1.22 * mycobacterium tuberculosis variant bovis 80000.0 2 PMID:22026918 -3.6.1.22 * rattus norvegicus 105000.0 1 PMID:9217009 -3.6.1.22 * saccharomyces cerevisiae 87000.0 2 PMID:10873676 -3.6.1.22 * salmonella enterica subsp. enterica serovar typhimurium 120000.0 1 PMID:6109709 -3.6.1.23 * acholeplasma laidlawii 48000.0 1 PMID:6145699 -3.6.1.23 * african swine fever virus 67000.0 3 PMID:31662460;PMID:31748385 -3.6.1.23 * allium cepa 36000.0 1 PMID:2153555 -3.6.1.23 * bacillus subtilis 48000.0 2 PMID:810487 -3.6.1.23 * drosophila melanogaster 69000.0 9 PMID:14724274;PMID:19232319;PMID:20412059;PMID:3025197 -3.6.1.23 * drosophila virilis 57900.0 2 PMID:27380921 -3.6.1.23 * equine infectious anemia virus 41000.0 2 PMID:9187238 -3.6.1.23 * escherichia coli 64500.0 3 PMID:3030754;PMID:346589 -3.6.1.23 * feline immunodeficiency virus 14300.0 1 PMID:8396797;PMID:8976551 -3.6.1.23 * homo sapiens 68000.0 8 PMID:1325640;PMID:285077;PMID:29531348;PMID:34584184;PMID:6130763;PMID:6143756;PMID:6147344 -3.6.1.23 * human alphaherpesvirus 1 53000.0 2 PMID:6143756;PMID:6147344 -3.6.1.23 * leishmania major 62850.0 4 PMID:10657253;PMID:11420444;PMID:15450848 -3.6.1.23 * methanocaldococcus jannaschii 136000.0 1 PMID:12909016 -3.6.1.23 * mycobacterium tuberculosis 25000.0 1 PMID:18164314 -3.6.1.23 * orthopoxvirus vaccinia 45000.0 2 PMID:8798559 -3.6.1.23 * paramecium bursaria chlorella virus 1 176000.0 2 PMID:16014955 -3.6.1.23 * pyrococcus woesei 22043.0 1 PMID:12963343 -3.6.1.23 * rana grylio virus 174000.0 1 PMID:16989917 -3.6.1.23 * rattus norvegicus 60000.0 3 PMID:3032103;PMID:39284464;PMID:6128977 -3.6.1.23 * saccharomyces cerevisiae 56600.0 2 PMID:21548881 -3.6.1.23 * shrimp white spot syndrome virus 70000.0 2 PMID:15845252 -3.6.1.23 * spbetavirus spbeta 48000.0 2 PMID:15939294 -3.6.1.23 * streptococcus mutans 16100.0 1 PMID:19342774 -3.6.1.23 * suid alphaherpesvirus 1 60000.0 1 PMID:3032103;PMID:39284464;PMID:6128977 -3.6.1.23 * sulfolobus virus stsv2 38000.0 1 * -3.6.1.23 * thermococcus onnurineus 43000.0 2 PMID:17549447 -3.6.1.23 * trypanosoma cruzi 64000.0 4 PMID:12208522 -3.6.1.24 * escherichia coli 23000.0 1 PMID:4318904 -3.6.1.25 * nitrosomonas europaea 19000.0 1 PMID:21840996 -3.6.1.25 * orthopoxvirus vaccinia 60000.0 1 PMID:9371657 -3.6.1.27 * bacillus subtilis 22000.0 1 PMID:15946938 -3.6.1.27 * escherichia coli 110000.0 4 PMID:18411271;PMID:24855653 -3.6.1.28 * bos taurus 33900.0 14 PMID:11827967;PMID:12943234;PMID:1329971;PMID:9784846 -3.6.1.28 * homo sapiens 27000.0 5 PMID:11827967;PMID:12943234;PMID:16000236 -3.6.1.28 * mus musculus 25000.0 1 PMID:18276586 -3.6.1.28 * rattus norvegicus 34000.0 6 PMID:12943234;PMID:4344228 -3.6.1.28 * sus scrofa 33900.0 2 PMID:12943234;PMID:16000236 -3.6.1.29 * artemia sp. 115000.0 1 PMID:1325380 -3.6.1.29 * escherichia coli 36000.0 1 PMID:2995162;PMID:3031018 -3.6.1.29 * homo sapiens 230000.0 3 PMID:10733886;PMID:16359767;PMID:2986968 -3.6.1.29 * lupinus luteus 41000.0 1 PMID:8954888 -3.6.1.29 * rattus norvegicus 36000.0 3 PMID:1849011;PMID:196848;PMID:2995162;PMID:3031018;PMID:6088316 -3.6.1.29 * saccharomyces cerevisiae 55000.0 1 PMID:1653209 -3.6.1.31 * arabidopsis sp. 31670.0 1 PMID:9733547 -3.6.1.31 * saccharomyces cerevisiae 95000.0 1 PMID:379004 -3.6.1.31 * salmonella enterica subsp. enterica serovar typhimurium 43000.0 1 PMID:14342333 -3.6.1.39 * bacillus subtilis 100000.0 1 PMID:4367957 -3.6.1.39 * homo sapiens 48500.0 5 PMID:1320895;PMID:2169414;PMID:6097526;PMID:6297538 -3.6.1.40 * escherichia coli 140000.0 3 PMID:6130093;PMID:8394006 -3.6.1.41 * badhamia polycephala 26000.0 1 PMID:6295456 -3.6.1.41 * escherichia coli 34000.0 3 PMID:2986688;PMID:6317672 -3.6.1.41 * shigella flexneri 32000.0 1 PMID:16511239 -3.6.1.41 * staphylococcus aureus 44000.0 1 PMID:32152217 -3.6.1.42 * bos taurus 46000.0 1 PMID:2989286 -3.6.1.42 * saccharomyces cerevisiae 57000.0 5 PMID:2172253;PMID:7540172;PMID:8391537;PMID:9614179 -3.6.1.45 * corynebacterium glutamicum 70460.0 2 PMID:16085822 -3.6.1.45 * escherichia coli 61000.0 3 PMID:2548058;PMID:3012467;PMID:6297400 -3.6.1.45 * mus musculus 54000.0 3 PMID:19896456 -3.6.1.45 * salmonella enterica subsp. enterica serovar typhimurium 28349.0 1 PMID:2548058 -3.6.1.45 * sus scrofa 60000.0 2 PMID:12429023 -3.6.1.45 * yersinia intermedia 63000.0 3 PMID:18641143 -3.6.1.5 * aedes aegypti 68000.0 1 PMID:16702045 -3.6.1.5 * arabidopsis thaliana 80000.0 3 PMID:21636723;PMID:22849572;PMID:25822168 -3.6.1.5 * bos taurus 78000.0 4 PMID:18976223 -3.6.1.5 * calliandra brevipes 75000.0 1 * -3.6.1.5 * cicer arietinum 50000.0 1 PMID:6275835 -3.6.1.5 * cimex lectularius 40000.0 1 PMID:9804829 -3.6.1.5 * cryptosporidium parvum 50000.0 2 PMID:22363541 -3.6.1.5 * ctenocephalides felis 57000.0 2 PMID:9887518 -3.6.1.5 * daboia russelii 83041.0 1 PMID:29325746 -3.6.1.5 * gallus gallus 85000.0 1 PMID:11985621 -3.6.1.5 * homo sapiens 78000.0 6 PMID:10858452;PMID:18295590;PMID:8187939;PMID:8955160;PMID:9033808 -3.6.1.5 * lathyrus oleraceus 49000.0 3 PMID:19820964 -3.6.1.5 * leishmania braziliensis 48000.0 4 PMID:19961654;PMID:22921497 -3.6.1.5 * leishmania infantum 50000.0 1 PMID:22995148 -3.6.1.5 * lupinus luteus 51000.0 1 PMID:1668272 -3.6.1.5 * mimosa pudica 67000.0 2 PMID:21788364 -3.6.1.5 * mus musculus 78000.0 4 PMID:11278936;PMID:11929769;PMID:15122917;PMID:15130768 -3.6.1.5 * ornithodoros savignyi 67000.0 2 PMID:14598857;PMID:19393241;PMID:9033808 -3.6.1.5 * phlebotomus duboscqi 50000.0 3 PMID:19651132 -3.6.1.5 * rattus norvegicus 140000.0 4 PMID:10231370;PMID:12694193;PMID:14598857;PMID:8673003;PMID:9033808 -3.6.1.5 * rhodnius prolixus 83000.0 1 PMID:3010945 -3.6.1.5 * solanum tuberosum 50077.0 10 PMID:12597881;PMID:19820964;PMID:23663929;PMID:4314055 -3.6.1.5 * sus scrofa 78000.0 6 PMID:10681547;PMID:10866813;PMID:12899702;PMID:6243296 -3.6.1.5 * taenia crassiceps 80000.0 1 PMID:18765260 -3.6.1.5 * triatoma infestans 205000.0 4 PMID:14985353;PMID:16542158 -3.6.1.5 * trypanosoma cruzi 69000.0 2 PMID:15020239 -3.6.1.52 * african swine fever virus 30000.0 1 PMID:11773415 -3.6.1.52 * homo sapiens 25000.0 5 PMID:10777568;PMID:12105228;PMID:12689335;PMID:9822604 -3.6.1.52 * mus musculus 25000.0 3 PMID:12105228;PMID:12689335;PMID:15212765 -3.6.1.52 * rattus norvegicus 18000.0 1 PMID:9822604 -3.6.1.53 * rattus norvegicus 40000.0 5 PMID:18352857;PMID:7819284 -3.6.1.54 * escherichia coli 26893.0 1 PMID:12000770 -3.6.1.55 * ciona intestinalis 20400.0 1 PMID:21178309 -3.6.1.55 * hordeum vulgare subsp. vulgare 18800.0 1 PMID:25379607 -3.6.1.56 * homo sapiens 17900.0 1 PMID:8226881 -3.6.1.56 * mus musculus 18000.0 2 PMID:7592783 -3.6.1.57 * campylobacter jejuni 32383.0 2 PMID:19483088 -3.6.1.59 * homo sapiens 38600.0 1 PMID:12198172 -3.6.1.59 * mus musculus 37921.0 1 PMID:16001405 -3.6.1.6 * acer pseudoplatanus 50000.0 1 * -3.6.1.6 * caenorhabditis elegans 53000.0 1 PMID:14688791 -3.6.1.6 * homo sapiens 43000.0 1 PMID:14529283 -3.6.1.6 * rattus norvegicus 140000.0 14 PMID:12167635;PMID:210795;PMID:210813;PMID:2828050;PMID:4373445;PMID:6256164;PMID:6293897;PMID:6320828 -3.6.1.6 * sporothrix schenckii 61580.0 1 PMID:23715619 -3.6.1.6 * staphylococcus aureus 25000.0 1 PMID:33955674 -3.6.1.6 * streptomyces coelicolor 25000.0 1 PMID:33955674 -3.6.1.6 * sus scrofa 155000.0 1 PMID:4354032 -3.6.1.60 * arabidopsis thaliana 26000.0 1 PMID:17824959 -3.6.1.60 * homo sapiens 18559.0 2 PMID:12121577 -3.6.1.60 * saccharomyces cerevisiae 21443.0 1 PMID:10085096 -3.6.1.61 * escherichia coli 20000.0 1 PMID:11479323 -3.6.1.61 * thermus thermophilus 14170.0 1 PMID:15024014 -3.6.1.62 * homo sapiens 22000.0 1 PMID:18607096 -3.6.1.62 * xenopus laevis 60000.0 2 PMID:17567574 -3.6.1.63 * escherichia coli 41700.0 1 PMID:1335942 -3.6.1.66 * trypanosoma brucei brucei 48000.0 1 PMID:35436992 -3.6.1.67 * arabidopsis thaliana 24200.0 2 PMID:15611104 -3.6.1.67 * escherichia coli 17000.0 2 PMID:4362677 -3.6.1.67 * lactococcus lactis 24200.0 2 PMID:15611104 -3.6.1.68 * rosa hybrid cultivar 16800.0 1 PMID:26138978 -3.6.1.7 * bos taurus 13200.0 2 PMID:14435883;PMID:237200 -3.6.1.7 * cavia porcellus 24000.0 2 PMID:6320809 -3.6.1.7 * deinococcus radiodurans 9000.0 1 PMID:37302289 -3.6.1.7 * drosophila melanogaster 11780.0 1 PMID:12560098 -3.6.1.7 * equus caballus 24200.0 11 PMID:237200;PMID:3001041;PMID:4305161;PMID:4344156;PMID:6314903;PMID:6320809 -3.6.1.7 * gallus gallus 12000.0 7 PMID:2830253;PMID:2830254;PMID:3001041 -3.6.1.7 * homo sapiens 11360.0 4 PMID:16511269;PMID:21643968;PMID:3026468;PMID:8746632 -3.6.1.7 * meleagris gallopavo 13400.0 4 PMID:1964788;PMID:6320809 -3.6.1.7 * oryctolagus cuniculus 23500.0 1 PMID:4313603 -3.6.1.7 * pyrococcus horikoshii 10130.0 4 PMID:15779887 -3.6.1.7 * rattus norvegicus 11000.0 1 PMID:1647162 -3.6.1.7 * saccharolobus solfataricus 10000.0 1 PMID:16508117 -3.6.1.7 * sus scrofa 11120.0 6 PMID:237200;PMID:2834344;PMID:6094516 -3.6.1.75 * saccharomyces cerevisiae 34000.0 4 PMID:11016943;PMID:11139591;PMID:14642771;PMID:8567632;PMID:9370315;PMID:9452443 -3.6.1.8 * badhamia polycephala 240000.0 2 PMID:238634 -3.6.1.8 * rattus norvegicus 120000.0 1 PMID:497237 -3.6.1.8 * sus scrofa 127000.0 2 PMID:7860751 -3.6.1.8 * thermococcus kodakarensis 49000.0 2 PMID:9016620 -3.6.1.9 * bos taurus 55000.0 1 PMID:25142936 -3.6.1.9 * bothrops jararaca 288000.0 1 PMID:19481561 -3.6.1.9 * brassica oleracea 55000.0 1 PMID:12631294 -3.6.1.9 * escherichia coli 45000.0 1 PMID:25658941 -3.6.1.9 * glaesserella parasuis 70000.0 1 PMID:21078;PMID:9453136 -3.6.1.9 * glycine max 560000.0 2 PMID:12228543 -3.6.1.9 * haemophilus influenzae 108100.0 2 PMID:3009442 -3.6.1.9 * homo sapiens 520000.0 7 PMID:11278832;PMID:22285541;PMID:25100243;PMID:3001038;PMID:8001561 -3.6.1.9 * lens culinaris 75000.0 1 PMID:10981813 -3.6.1.9 * mus musculus 240000.0 4 PMID:20048161;PMID:4360250;PMID:8001561 -3.6.1.9 * opuntia ficus-indica 105000.0 2 * -3.6.1.9 * oryza sativa 374000.0 6 PMID:24092883 -3.6.1.9 * rattus sp. 500000.0 4 PMID:1149736;PMID:7532398 -3.6.1.9 * saccharomyces sp. 65000.0 2 PMID:4401058 -3.6.1.9 * solanum tuberosum 346000.0 3 PMID:6147251 -3.6.1.9 * thermotoga maritima 29728.0 1 PMID:12657645 -3.6.1.9 * vigna radiata var. radiata 70000.0 4 PMID:21078;PMID:9453136 -3.6.2.1 * bos taurus 69000.0 4 PMID:214136;PMID:4348176 -3.6.4.6 * arabidopsis thaliana 50000.0 2 PMID:17468262 -3.6.4.6 * helicoverpa armigera 28000.0 1 PMID:16386334 -3.6.4.6 * homo sapiens 300000.0 3 PMID:18550891;PMID:9588209 -3.6.4.6 * komagataella pastoris 400000.0 1 PMID:9447990 -3.6.4.6 * mus musculus 148000.0 3 PMID:18796009 -3.6.4.6 * rattus norvegicus 89000.0 1 PMID:16601695 -3.6.4.6 * saccharolobus solfataricus 42248.0 2 PMID:24161953 -3.6.4.6 * saccharomyces cerevisiae 245000.0 5 PMID:24161953;PMID:9155008;PMID:9211789;PMID:9606181 -3.6.4.7 * arabidopsis thaliana 98000.0 1 PMID:17478548 -3.6.4.7 * homo sapiens 143000.0 3 PMID:18208396;PMID:7493019 -3.6.4.7 * ogataea angusta 104900.0 1 PMID:17172804 -3.6.4.7 * penicillium chrysogenum 1100000.0 2 PMID:22733816 -3.6.4.7 * saccharomyces cerevisiae 700000.0 7 PMID:22710083;PMID:26066397;PMID:26842748 -3.6.5.1 * arabidopsis thaliana 45000.0 1 * -3.6.5.1 * bos taurus 80000.0 12 PMID:3115314;PMID:3117105;PMID:7890762 -3.6.5.1 * secale cereale 45000.0 1 * -3.6.5.2 * bacillus subtilis 45000.0 1 PMID:17981968 -3.6.5.2 * bos taurus 26000.0 2 PMID:9799233 -3.6.5.2 * candida albicans 21100.0 1 PMID:19095072 -3.6.5.2 * homo sapiens 200000.0 6 PMID:15561770;PMID:1784275;PMID:28126905;PMID:9799233 -3.6.5.2 * plasmodium falciparum 108570.0 1 PMID:26540393 -3.6.5.2 * pseudomonas aeruginosa 48000.0 1 PMID:9079902 -3.6.5.2 * rattus sp. 30030.0 1 PMID:10727423 -3.6.5.2 * trypanosoma brucei 21803.0 4 PMID:23184293 -3.6.5.3 * escherichia coli 43000.0 1 PMID:3308869 -3.6.5.3 * hemicentrotus pulcherrimus 51000.0 1 PMID:2105945 -3.6.5.3 * oryctolagus cuniculus 52000.0 5 PMID:8536702;PMID:8722024 -3.6.5.3 * pseudocentrotus depressus 51000.0 1 PMID:2105945 -3.6.5.3 * pseudomonas aeruginosa 45000.0 1 PMID:9211936 -3.6.5.3 * rattus norvegicus 95000.0 4 PMID:3338467;PMID:6566615 -3.6.5.3 * saccharolobus solfataricus 70000.0 7 PMID:17608795;PMID:1907914;PMID:19375481;PMID:22554723;PMID:9030774;PMID:9893948 -3.6.5.3 * saccharomyces pastorianus 125000.0 1 PMID:2839469 -3.6.5.3 * schizosaccharomyces pombe 120000.0 5 PMID:2839469 -3.6.5.3 * triticum aestivum 150000.0 1 PMID:1637870 -3.6.5.3 * xenopus laevis 58000.0 1 PMID:8722024 -3.6.5.4 * acidianus ambivalens 50400.0 2 PMID:9133659;PMID:9914525 -3.6.5.4 * arabidopsis thaliana 54000.0 4 PMID:18621669;PMID:19636919 -3.6.5.4 * bacillus cereus 50200.0 1 PMID:17660418 -3.6.5.4 * canis lupus familiaris 69000.0 2 PMID:7844142;PMID:8383841 -3.6.5.4 * escherichia coli 400000.0 3 PMID:16923832;PMID:8247130 -3.6.5.4 * mycoplasma mycoides 68000.0 6 PMID:7844142;PMID:8383841;PMID:9179846;PMID:9630516 -3.6.5.4 * pyrococcus furiosus 35810.0 2 PMID:18978942 -3.6.5.4 * streptomyces coelicolor 36000.0 2 PMID:16820862 -3.6.5.5 * arabidopsis thaliana 69800.0 2 PMID:16824181;PMID:22232176 -3.6.5.5 * bos taurus 100000.0 1 PMID:1311055 -3.6.5.5 * homo sapiens 330000.0 8 PMID:18590784;PMID:21840923;PMID:23027751;PMID:23530241;PMID:31328044;PMID:7962076 -3.6.5.5 * mus musculus 100000.0 2 PMID:17133603;PMID:17525220 -3.6.5.5 * plasmodium falciparum 83000.0 1 PMID:17533148 -3.6.5.5 * rattus norvegicus 100000.0 1 PMID:1421574 -3.6.5.6 * bacillus thuringiensis 54400.0 1 PMID:17873046 -3.6.5.6 * bos taurus 220000.0 5 PMID:16675842;PMID:8193140 -3.6.5.6 * mus musculus 50130.0 3 PMID:16675842 -3.6.5.6 * rattus norvegicus 55000.0 1 PMID:2160472;PMID:8631991 -3.6.5.6 * sus scrofa 128000.0 5 PMID:2160472;PMID:8631991 -3.7.1.1 * aspergillus niger 440000.0 8 PMID:10778746;PMID:179820;PMID:19133276 -3.7.1.1 * botrytis cinerea 100000.0 3 PMID:17244616 -3.7.1.11 * azoarcus sp. 120000.0 6 PMID:21965568 -3.7.1.13 * janthinobacterium sp. j3 70000.0 2 PMID:12619671;PMID:12659866 -3.7.1.13 * metapseudomonas resinovorans 70000.0 5 PMID:12619671;PMID:12659866 -3.7.1.13 * pseudomonas sp. 33000.0 2 PMID:12651123 -3.7.1.14 * escherichia coli 62000.0 3 PMID:15663942;PMID:9098055 -3.7.1.17 * mycobacterium tuberculosis 132000.0 2 PMID:19014350 -3.7.1.18 * rhodococcus sp. (in: high g+c gram-positive bacteria) 83000.0 2 PMID:11278926 -3.7.1.19 * paenarthrobacter nicotinovorans 43555.0 2 PMID:16321959 -3.7.1.2 * arabidopsis thaliana 65000.0 1 PMID:22980205 -3.7.1.2 * bos taurus 87000.0 2 PMID:13916;PMID:7213744 -3.7.1.2 * caenorhabditis elegans 46000.0 1 PMID:18227072 -3.7.1.2 * exiguobacterium antarcticum 66000.0 2 PMID:30630595 -3.7.1.2 * homo sapiens 83000.0 4 PMID:1998338;PMID:2195095 -3.7.1.2 * mus musculus 46000.0 2 PMID:10508789;PMID:15934927 -3.7.1.2 * rattus norvegicus 43000.0 2 PMID:1916290;PMID:8422430 -3.7.1.2 * rhodotorula diobovata 66000.0 2 PMID:25832819 -3.7.1.2 * thermus thermophilus 29400.0 1 PMID:17768357 -3.7.1.20 * ralstonia sp. 21000.0 1 PMID:11133965 -3.7.1.21 * geobacter metallireducens 240000.0 3 PMID:18312395 -3.7.1.21 * syntrophus aciditrophicus 265000.0 3 PMID:18312395 -3.7.1.21 * thauera aromatica 170000.0 2 PMID:10406950 -3.7.1.22 * rhizobium leguminosarum 66730.0 1 PMID:11497462 -3.7.1.23 * aquipseudomonas alcaligenes 77000.0 4 PMID:23204427;PMID:7400101 -3.7.1.24 * pseudomonas fluorescens 40000.0 1 PMID:16391073 -3.7.1.24 * pseudomonas sp. 65000.0 2 PMID:22790955 -3.7.1.25 * cupriavidus necator 116000.0 2 * -3.7.1.25 * pseudomonas putida 65000.0 1 * -3.7.1.3 * bombyx mori 49000.0 2 PMID:19170761 -3.7.1.3 * homo sapiens 130000.0 5 PMID:11985583;PMID:14505498;PMID:1772066 -3.7.1.3 * neurospora crassa 110000.0 3 PMID:136367;PMID:156178;PMID:162555 -3.7.1.3 * pseudomonas fluorescens 45820.0 2 PMID:9264543 -3.7.1.3 * pseudomonas marginalis 100000.0 4 PMID:162555;PMID:4730493 -3.7.1.3 * rattus norvegicus 95000.0 2 PMID:4008484;PMID:7451426 -3.7.1.3 * streptomyces parvulus 82000.0 1 PMID:6153909 -3.7.1.3 * suncus murinus 110000.0 1 PMID:1772066 -3.7.1.3 * sus scrofa 100000.0 1 PMID:457635 -3.7.1.4 * eubacterium ramulus 55000.0 5 PMID:15466559 -3.7.1.4 * homo sapiens 250000.0 1 PMID:27773655 -3.7.1.4 * oryctolagus cuniculus 220000.0 1 PMID:14972028 -3.7.1.5 * agrobacterium sp. 72000.0 1 PMID:4375963 -3.7.1.5 * homo sapiens 28000.0 1 PMID:21878618 -3.7.1.6 * pseudomonas putida 38000.0 1 PMID:10438778;PMID:236305 -3.7.1.7 * nostoc sp. pcc 7120 = fachb-418 30000.0 2 PMID:17198383 -3.7.1.7 * pseudomonas sp. 40610.0 2 PMID:10746768;PMID:15934927 -3.7.1.7 * sphingomonas sp. 70000.0 2 PMID:15817792 -3.7.1.7 * sphingopyxis sp. 35000.0 1 PMID:21695541 -3.7.1.8 * bacillus sp. (in: firmicutes) 33000.0 1 PMID:16339959 -3.7.1.8 * dyella ginsengisoli 32000.0 1 PMID:23494625 -3.7.1.8 * pseudomonas sp. 55000.0 2 PMID:12651123 -3.7.1.8 * pseudomonas sp. 'cruciviae' 160000.0 2 * -3.7.1.8 * rhodococcus globerulus 32580.0 1 PMID:11160080 -3.7.1.8 * sphingomonas sp. 48000.0 4 PMID:7764304 -3.7.1.9 * arthrobacter sp. 31840.0 1 PMID:10746195 -3.7.1.9 * cupriavidus necator 116000.0 4 * -3.7.1.9 * flavobacterium sp. 120000.0 2 PMID:17078928 -3.7.1.9 * pseudomonas fluorescens 58000.0 3 PMID:16233251 -3.7.1.9 * pseudomonas putida 65000.0 2 PMID:1791759 -3.7.1.9 * pseudomonas sp. 30965.0 2 PMID:2194577;PMID:23009925 -3.8.1.10 * pseudomonas sp. 68000.0 6 PMID:7068529;PMID:7103659;PMID:8074519;PMID:9209038 -3.8.1.2 * agrobacterium sp. 31000.0 1 PMID:15865161 -3.8.1.2 * ancylobacter aquaticus 25000.0 2 PMID:26645146 -3.8.1.2 * azotobacter sp. 29000.0 2 * -3.8.1.2 * burkholderia cepacia 58000.0 3 PMID:10498712;PMID:7579997;PMID:8074519 -3.8.1.2 * pseudoalteromonas sp. 32500.0 2 * -3.8.1.2 * pseudomonas putida 79000.0 8 PMID:1556080;PMID:1588303;PMID:26508534;PMID:7764511 -3.8.1.2 * pseudomonas sp. 64000.0 11 PMID:10498712;PMID:1772590;PMID:1995594;PMID:6873881;PMID:7579997;PMID:7944368;PMID:8074519 -3.8.1.2 * pyrococcus horikoshii 49700.0 2 PMID:18931414 -3.8.1.2 * rhizobium sp. 60000.0 4 PMID:8654424 -3.8.1.2 * rhodobacteraceae bacterium udc319 25600.0 2 PMID:23384397 -3.8.1.2 * sulfurisphaera tokodaii 50000.0 2 PMID:17642519 -3.8.1.2 * xanthobacter autotrophicus 38000.0 5 PMID:1744048 -3.8.1.3 * moraxella sp. 67000.0 4 * -3.8.1.3 * mus musculus 41000.0 2 PMID:6432789 -3.8.1.3 * pseudomonas sp. 42000.0 2 * -3.8.1.5 * ancylobacter aquaticus 35144.0 2 PMID:24642226 -3.8.1.5 * arthrobacter sp. 37000.0 1 PMID:3667524 -3.8.1.5 * bradyrhizobium elkanii 35000.0 1 PMID:19342778;PMID:28587829 -3.8.1.5 * corynebacterium sp. 36000.0 2 PMID:3624201;PMID:4019411 -3.8.1.5 * haloferax mediterranei 143000.0 1 PMID:37574754 -3.8.1.5 * mycobacterium avium 36000.0 1 PMID:17084094 -3.8.1.5 * mycobacterium tuberculosis variant bovis 34500.0 1 PMID:16269704 -3.8.1.5 * mycolicibacterium rhodesiae 150000.0 3 PMID:25899475 -3.8.1.5 * plesiocystis pacifica 32600.0 1 PMID:21603934 -3.8.1.5 * rhodococcus erythropolis 34000.0 1 PMID:2351952 -3.8.1.5 * rhodococcus rhodochrous 35000.0 1 PMID:19342778;PMID:28587829 -3.8.1.5 * sphingobium indicum 58000.0 2 PMID:16957186 -3.8.1.5 * sphingomonas paucimobilis 34800.0 5 PMID:14744129;PMID:16216524;PMID:9293022 -3.8.1.5 * strongylocentrotus purpuratus 36000.0 1 PMID:23939220 -3.8.1.5 * uncultured bacterium 37900.0 2 PMID:28674849 -3.8.1.5 * xanthobacter autotrophicus 36000.0 2 PMID:3624201;PMID:4019411 -3.8.1.5 * yarrowia lipolytica 43000.0 1 PMID:28928379 -3.8.1.6 * arthrobacter sp. 50000.0 1 * -3.8.1.7 * arthrobacter sp. 131000.0 4 PMID:15068371;PMID:7765837 -3.8.1.7 * pseudomonas sp. 122000.0 9 PMID:1610806;PMID:20363940;PMID:7579994;PMID:7765837 -3.8.1.8 * arthrobacter sp. 54000.0 1 * -3.8.1.8 * pseudomonas sp. 315000.0 4 PMID:17660279;PMID:25760618;PMID:8759853 -3.8.1.8 * rhizobium sp. 200000.0 2 PMID:16535552 -3.8.1.9 * agrobacterium sp. 53000.0 2 PMID:15865161 -3.8.1.9 * pseudomonas putida 135000.0 2 PMID:2380688 -3.8.1.9 * rhizobium sp. 60000.0 3 PMID:8654424 -3.8.2.2 * alteromonas sp. 60000.0 2 PMID:20000741;PMID:2001997 -3.8.2.2 * brevundimonas diminuta 35000.0 1 PMID:20890601 -3.8.2.2 * doryteuthis pealeii 42000.0 1 PMID:8393747 -3.8.2.2 * homo sapiens 73000.0 1 PMID:16122899 -3.8.2.2 * loligo vulgaris 35220.0 2 PMID:11162408;PMID:21041927 -3.8.2.2 * pseudoalteromonas undina 53000.0 1 PMID:16349054 -3.8.2.2 * pseudomonas aeruginosa 58500.0 1 PMID:21597641 -3.8.2.2 * rangia cuneata 100000.0 3 * -3.8.2.2 * rattus norvegicus 34000.0 2 PMID:15251439 -3.8.2.2 * todarodes pacificus 34000.0 1 PMID:8263902 -3.9.1.3 * caenorhabditis elegans 14000.0 1 PMID:12383260;PMID:12468887;PMID:16219293;PMID:17200567;PMID:18796614;PMID:18991813;PMID:19344975;PMID:23205079;PMID:26537769 -3.9.1.3 * escherichia coli 14000.0 1 PMID:12383260;PMID:12468887;PMID:16219293;PMID:17200567;PMID:18796614;PMID:18991813;PMID:19344975;PMID:23205079;PMID:26537769 -3.9.1.3 * homo sapiens 600000.0 11 PMID:12383260;PMID:12468887;PMID:16219293;PMID:17200567;PMID:18796614;PMID:18991813;PMID:19138678;PMID:19344975;PMID:21876758;PMID:21967643;PMID:23205079;PMID:26537769 -3.9.1.3 * mus musculus 14000.0 1 PMID:12383260;PMID:12468887;PMID:16219293;PMID:17200567;PMID:18796614;PMID:18991813;PMID:19344975;PMID:23205079;PMID:26537769 -3.9.1.3 * oryctolagus cuniculus 14000.0 1 PMID:12383260;PMID:12468887;PMID:16219293;PMID:17200567;PMID:18796614;PMID:18991813;PMID:19344975;PMID:23205079;PMID:26537769 -3.9.1.3 * rattus norvegicus 16000.0 2 PMID:12383260;PMID:12468887;PMID:16219293;PMID:17200567;PMID:18796614;PMID:18991813;PMID:19344975;PMID:20501872;PMID:23205079;PMID:26537769 -3.9.1.3 * sus scrofa 14000.0 3 PMID:12383260;PMID:12468887;PMID:16219293;PMID:17200567;PMID:18796614;PMID:18991813;PMID:19344975;PMID:23205079;PMID:26537769 -4.1.1.1 * [bacillus] caldolyticus 41700.0 2 * -4.1.1.1 * acetobacter pasteurianus 58873.0 1 PMID:11734888 -4.1.1.1 * chlamydomonas reinhardtii 65000.0 1 PMID:18245276 -4.1.1.1 * fragaria x ananassa 65300.0 1 * -4.1.1.1 * gluconacetobacter diazotrophicus 60000.0 4 PMID:24276622;PMID:25369873 -4.1.1.1 * gluconobacter oxydans 60800.0 2 PMID:24276622 -4.1.1.1 * hanseniaspora uvarum 210000.0 2 PMID:7725793 -4.1.1.1 * ipomoea batatas 240000.0 2 PMID:1101964;PMID:15155220;PMID:15876566;PMID:5400;PMID:7154965 -4.1.1.1 * kluyveromyces lactis 240000.0 4 PMID:12084066;PMID:16939618 -4.1.1.1 * komagataella pastoris 66000.0 1 PMID:23423327 -4.1.1.1 * lactococcus lactis 240000.0 3 PMID:15155220;PMID:15358422;PMID:15876566;PMID:1588311;PMID:3546263 -4.1.1.1 * nakaseomyces glabratus 150000.0 4 PMID:15625313 -4.1.1.1 * oryza sativa 240000.0 3 PMID:17761427;PMID:2269301 -4.1.1.1 * parageobacillus thermoglucosidasius 60800.0 2 PMID:24276622;PMID:25369873 -4.1.1.1 * pseudothermotoga hypogea 157000.0 5 PMID:26032540 -4.1.1.1 * rhizopus arrhizus 272000.0 6 * -4.1.1.1 * saccharomyces cerevisiae 240000.0 19 PMID:10433706;PMID:1101964;PMID:11248689;PMID:11781083;PMID:12034445;PMID:15155220;PMID:15876566;PMID:16939618;PMID:23423327;PMID:24818692;PMID:5400;PMID:7154965;PMID:8828822 -4.1.1.1 * sarcina ventriculi 240000.0 4 PMID:11535783;PMID:15155220;PMID:15358422;PMID:15876566;PMID:1588311;PMID:17651394;PMID:3546263 -4.1.1.1 * thermococcus guaymasensis 258000.0 5 PMID:24982594 -4.1.1.1 * thermococcus kodakarensis 240000.0 1 PMID:15155220;PMID:15358422;PMID:15876566;PMID:1588311;PMID:3546263 -4.1.1.1 * thermotoga maritima 156000.0 5 PMID:26032540 -4.1.1.1 * triticum aestivum 390000.0 1 PMID:3305013 -4.1.1.1 * tritrichomonas suis 240000.0 2 PMID:1101964;PMID:15155220;PMID:15358422;PMID:15876566;PMID:1588311;PMID:3546263;PMID:5400;PMID:7154965 -4.1.1.1 * zygosaccharomyces bisporus 244000.0 3 PMID:10839465 -4.1.1.1 * zymobacter palmae 63000.0 2 PMID:15968504;PMID:27599861 -4.1.1.1 * zymomonas mobilis 240000.0 13 PMID:10924138;PMID:1101964;PMID:15155220;PMID:15358422;PMID:1586459;PMID:15876566;PMID:1588311;PMID:18034308;PMID:18368298;PMID:25524103;PMID:3546263;PMID:5400;PMID:7154965 -4.1.1.101 * lacticaseibacillus casei 130000.0 2 PMID:16346657 -4.1.1.101 * lactiplantibacillus plantarum 140000.0 3 PMID:21404095;PMID:6833282 -4.1.1.101 * lactococcus lactis 60000.0 2 PMID:8405453 -4.1.1.101 * leuconostoc mesenteroides 235000.0 3 PMID:16345941;PMID:16346657 -4.1.1.101 * ligilactobacillus murinus 220000.0 2 PMID:6536648 -4.1.1.101 * oenococcus oeni 132000.0 8 PMID:16346657;PMID:2097345;PMID:22452826;PMID:8919788 -4.1.1.102 * bacillus pumilus 42000.0 3 PMID:8534115 -4.1.1.102 * enterobacter sp. 23000.0 1 PMID:21085952 -4.1.1.102 * meyerozyma guilliermondii 19828.0 1 PMID:22217315 -4.1.1.102 * pseudomonas fluorescens 40400.0 2 PMID:7928951 -4.1.1.102 * saccharomyces cerevisiae 480000.0 1 PMID:25647642 -4.1.1.103 * agrobacterium tumefaciens 138000.0 4 PMID:15118811;PMID:15474471 -4.1.1.103 * rhizobium sp. 151000.0 2 PMID:15466039 -4.1.1.105 * bacillus sp. (in: firmicutes) 150000.0 1 PMID:4036551 -4.1.1.105 * catharanthus roseus 115000.0 2 PMID:21080162;PMID:24310513 -4.1.1.106 * chlorella variabilis 401000.0 1 PMID:32348726 -4.1.1.109 * petunia x hybrida 250000.0 1 PMID:16766535 -4.1.1.11 * corynebacterium glutamicum 14100.0 1 PMID:10103247 -4.1.1.11 * drosophila melanogaster 58000.0 1 PMID:15878647 -4.1.1.11 * escherichia coli 59000.0 7 PMID:14633979;PMID:16525887;PMID:3003510;PMID:381298;PMID:9169598 -4.1.1.11 * mycobacterium tuberculosis 64000.0 2 PMID:12182836 -4.1.1.11 * priestia aryabhattai 52800.0 1 PMID:36708489 -4.1.1.11 * pyrococcus furiosus 41000.0 2 * -4.1.1.11 * salmonella enterica 55600.0 1 PMID:22497218 -4.1.1.11 * tribolium castaneum 109000.0 1 PMID:31696283 -4.1.1.110 * picrophilus oshimae 75700.0 1 PMID:35690147 -4.1.1.110 * thermoplasma acidophilum 89000.0 1 PMID:28004831 -4.1.1.111 * desulfovibrio desulfuricans 94000.0 4 PMID:24669201;PMID:24865947 -4.1.1.111 * methanosarcina barkeri 40000.0 1 PMID:24865947 -4.1.1.111 * nitratidesulfovibrio vulgaris 40000.0 1 PMID:24865947 -4.1.1.112 * acetobacter aceti 80000.0 1 * -4.1.1.112 * corynebacterium glutamicum 118000.0 5 PMID:20233922;PMID:7771770 -4.1.1.112 * saccharolobus solfataricus 105000.0 2 PMID:3142524 -4.1.1.112 * stutzerimonas stutzeri 63000.0 1 PMID:10222034 -4.1.1.112 * vibrio cholerae 570000.0 1 PMID:15647905 -4.1.1.112 * vibrio cholerae serotype o1 530000.0 4 PMID:17270211;PMID:21209096 -4.1.1.112 * zea mays 58000.0 1 * -4.1.1.119 * uncultured bacterium 200000.0 1 PMID:31512343 -4.1.1.12 * acinetobacter radioresistens 684.0 1 PMID:33760222 -4.1.1.12 * aedes aegypti 110000.0 1 PMID:19842059 -4.1.1.12 * comamonas testosteroni 61000.0 2 * -4.1.1.12 * mycobacterium tuberculosis 64000.0 2 PMID:12182836 -4.1.1.12 * pseudomonas dacunhae 820000.0 2 PMID:5773301 -4.1.1.12 * pseudomonas sp. 760000.0 5 PMID:16847601 -4.1.1.129 * chondromyces crocatus 60157.0 2 PMID:20080978 -4.1.1.130 * saccharomyces cerevisiae 38600.0 1 PMID:11469793 -4.1.1.15 * anopheles gambiae 110000.0 1 PMID:18256502;PMID:19842059;PMID:28101806;PMID:3468504 -4.1.1.15 * arabidopsis sp. 58000.0 2 PMID:9701597 -4.1.1.15 * arabidopsis thaliana 342000.0 5 PMID:19580813;PMID:25614413 -4.1.1.15 * aspergillus oryzae 300000.0 2 * -4.1.1.15 * brucella microti 307400.0 1 PMID:25853037 -4.1.1.15 * clostridium perfringens 290000.0 1 PMID:3910996 -4.1.1.15 * cucurbita maxima 340000.0 3 * -4.1.1.15 * enterococcus raffinosus 110000.0 1 PMID:18256502;PMID:19842059;PMID:28101806;PMID:3468504 -4.1.1.15 * escherichia coli 324000.0 7 PMID:17253644;PMID:22312257;PMID:27438707;PMID:3910996 -4.1.1.15 * felis catus 110000.0 2 PMID:8080275 -4.1.1.15 * gallus gallus 42000.0 1 PMID:19895308 -4.1.1.15 * glycine max 57000.0 1 PMID:19393555 -4.1.1.15 * homo sapiens 140000.0 4 PMID:658037 -4.1.1.15 * hordeum vulgare 310000.0 3 PMID:1167156 -4.1.1.15 * lacticaseibacillus paracasei 110000.0 2 PMID:18256502;PMID:19842059;PMID:28101806;PMID:3468504 -4.1.1.15 * lactiplantibacillus plantarum 109600.0 2 PMID:33990858 -4.1.1.15 * levilactobacillus brevis 350000.0 14 PMID:18460820;PMID:22418267;PMID:23563537;PMID:25047135;PMID:29167934;PMID:34153863;PMID:9255981 -4.1.1.15 * macaca fuscata 66000.0 1 PMID:18776697 -4.1.1.15 * monascus purpureus 153000.0 2 * -4.1.1.15 * mus musculus 86000.0 3 PMID:4700449 -4.1.1.15 * neurospora crassa 33200.0 2 PMID:1825829 -4.1.1.15 * oryza sativa 78000.0 4 PMID:20355143 -4.1.1.15 * petunia sp. 680000.0 4 PMID:16603423 -4.1.1.15 * pinus pinaster 57200.0 2 PMID:20859639 -4.1.1.15 * pyrococcus furiosus 41000.0 2 * -4.1.1.15 * pyrococcus horikoshii 43000.0 2 PMID:19129626 -4.1.1.15 * rattus norvegicus 120000.0 8 PMID:18256502;PMID:19578718;PMID:19842059;PMID:20969567;PMID:28101806;PMID:3468504 -4.1.1.15 * solanum tuberosum 91000.0 2 PMID:2862040 -4.1.1.15 * streptococcus thermophilus 103600.0 3 * -4.1.1.15 * sus scrofa 118000.0 2 PMID:8125937 -4.1.1.15 * synechocystis sp. pcc 6803 55000.0 1 PMID:26730883 -4.1.1.15 * vicia faba 58000.0 2 PMID:23411329 -4.1.1.15 * zea mays 61000.0 2 * -4.1.1.17 * aspergillus terreus 110000.0 1 PMID:2506167;PMID:2669750;PMID:2953728;PMID:31362455 -4.1.1.17 * badhamia polycephala 80000.0 2 PMID:6706929 -4.1.1.17 * corchorus olitorius 39000.0 1 * -4.1.1.17 * entamoeba histolytica 216000.0 10 PMID:12594962;PMID:18235846;PMID:19520076;PMID:22389745;PMID:8786214 -4.1.1.17 * erythroxylum coca 44522.0 1 PMID:22311164 -4.1.1.17 * escherichia coli 81000.0 2 PMID:6353148 -4.1.1.17 * grateloupia imbricata 45970.0 1 PMID:19524320 -4.1.1.17 * hordeum vulgare 55000.0 1 * -4.1.1.17 * lactobacillus sp. 1040000.0 2 PMID:7380847 -4.1.1.17 * lactobacillus sp. 30a 990600.0 2 PMID:10666573 -4.1.1.17 * ligilactobacillus saerimneri 30a 84000.0 1 PMID:23316036 -4.1.1.17 * mus musculus 170000.0 9 PMID:11960919;PMID:1959325;PMID:3392002;PMID:3753469;PMID:6621384 -4.1.1.17 * neurospora crassa 110000.0 2 PMID:2506167;PMID:2669750;PMID:2953728;PMID:31362455 -4.1.1.17 * nicotiana glutinosa 92000.0 3 PMID:11736657;PMID:22389745 -4.1.1.17 * oenococcus oeni 85000.0 1 PMID:21819657 -4.1.1.17 * panagrellus redivivus 90000.0 3 PMID:7772052;PMID:8694755 -4.1.1.17 * pelophylax nigromaculatus 190000.0 3 PMID:1959325 -4.1.1.17 * plasmodium falciparum 330000.0 1 PMID:12974675 -4.1.1.17 * pseudomonas savastanoi pv. phaseolicola 160000.0 3 * -4.1.1.17 * rattus norvegicus 250000.0 12 PMID:2506167;PMID:2669750;PMID:2953728;PMID:3036823;PMID:31362455;PMID:5073764;PMID:6498217;PMID:6621383;PMID:6691994 -4.1.1.17 * saccharomyces cerevisiae 110000.0 2 PMID:2506167;PMID:2669750;PMID:2953728;PMID:31362455;PMID:6621383 -4.1.1.17 * tetrahymena pyriformis 64000.0 1 PMID:3931682 -4.1.1.17 * tetrahymena thermophila 68000.0 1 PMID:2600881 -4.1.1.17 * thermus thermophilus 135000.0 2 PMID:10395069 -4.1.1.17 * trichomonas vaginalis 210000.0 2 PMID:8343128 -4.1.1.17 * trypanosoma brucei 100000.0 4 PMID:3036823;PMID:3056933;PMID:5073764 -4.1.1.18 * aliivibrio salmonicida 780000.0 2 * -4.1.1.18 * bacterium cadaveris 1000000.0 1 PMID:5762458 -4.1.1.18 * burkholderia sp. 150000.0 2 PMID:24863180 -4.1.1.18 * escherichia coli 800000.0 8 PMID:18989633;PMID:21148420;PMID:30619163;PMID:4590109;PMID:6353151;PMID:9226257 -4.1.1.18 * glycine max 95000.0 1 PMID:9633596 -4.1.1.18 * hafnia alvei 1174000.0 6 * -4.1.1.18 * ligilactobacillus saerimneri 30a 85000.0 1 PMID:23316036 -4.1.1.18 * selenomonas ruminantium 88000.0 4 PMID:10427692;PMID:6401702 -4.1.1.18 * vibrio parahaemolyticus 531000.0 2 PMID:1799949 -4.1.1.18 * vibrio vulnificus 800000.0 1 PMID:30619163;PMID:9226257 -4.1.1.19 * avena sativa 195000.0 8 PMID:19063883 -4.1.1.19 * bacillus subtilis 58000.0 1 PMID:18256468;PMID:19255484 -4.1.1.19 * brassica rapa subsp. oleifera 240000.0 1 PMID:9399439 -4.1.1.19 * chlamydia pneumoniae 88000.0 3 PMID:17693492 -4.1.1.19 * chlamydia trachomatis 25000.0 1 PMID:19607664 -4.1.1.19 * datura stramonium 63000.0 1 PMID:19234674 -4.1.1.19 * dianthus caryophyllus 327000.0 2 PMID:15120115 -4.1.1.19 * erythroxylum coca 72821.0 1 PMID:22311164 -4.1.1.19 * escherichia coli 820000.0 5 PMID:19298070;PMID:6353148 -4.1.1.19 * glycine max 240000.0 2 PMID:9399439 -4.1.1.19 * helicobacter pylori 407000.0 1 PMID:29684243 -4.1.1.19 * humulus lupulus 54000.0 2 PMID:21415599 -4.1.1.19 * lathyrus sativus 220000.0 1 PMID:1252 -4.1.1.19 * malus domestica 78000.0 1 PMID:15723827 -4.1.1.19 * methanocaldococcus jannaschii 55900.0 1 PMID:11980912 -4.1.1.19 * mycolicibacterium smegmatis 232000.0 2 PMID:2667997 -4.1.1.19 * oryza sativa 176000.0 5 PMID:16769152;PMID:20082138 -4.1.1.19 * prunus persica 77700.0 1 PMID:18996450 -4.1.1.19 * rattus norvegicus 39400.0 1 PMID:23840524 -4.1.1.19 * saccharolobus solfataricus 80000.0 4 PMID:18650422 -4.1.1.19 * salmonella enterica subsp. enterica serovar typhimurium 800000.0 1 PMID:28694189 -4.1.1.19 * selenomonas ruminantium 120000.0 2 PMID:18256468;PMID:19255484 -4.1.1.19 * thermococcus kodakarensis 99400.0 2 PMID:18702616 -4.1.1.19 * yersinia pestis 178000.0 3 PMID:15583399 -4.1.1.2 * agaricus bisporus 118000.0 3 PMID:20464388 -4.1.1.2 * agrobacterium tumefaciens 44700.0 2 PMID:18667852 -4.1.1.2 * bacillus subtilis 264000.0 11 PMID:10960116;PMID:11546787;PMID:12056897;PMID:14973022;PMID:15475346;PMID:18946701;PMID:23971028 -4.1.1.2 * dichomitus squalens 110000.0 1 PMID:20464388 -4.1.1.2 * flammulina velutipes 560000.0 6 PMID:10702293;PMID:1748632;PMID:20464388;PMID:26798990 -4.1.1.2 * phanerodontia chrysosporium 104000.0 1 PMID:20464388 -4.1.1.2 * photorhabdus luminescens 120000.0 1 * -4.1.1.2 * pseudomonas sp. 240000.0 1 PMID:35007451 -4.1.1.2 * trametes versicolor 118000.0 3 * -4.1.1.20 * arabidopsis thaliana 100000.0 5 PMID:30962284 -4.1.1.20 * bacillus anthracis 83000.0 1 PMID:26921318 -4.1.1.20 * bacillus subtilis 105000.0 1 PMID:234936 -4.1.1.20 * corynebacterium glutamicum 95000.0 3 PMID:21848075;PMID:29233695 -4.1.1.20 * escherichia coli 200000.0 3 PMID:11856852;PMID:26921318 -4.1.1.20 * lysinibacillus sphaericus 80000.0 1 * -4.1.1.20 * methanocaldococcus jannaschii 50000.0 1 PMID:12429091 -4.1.1.20 * mycobacterium tuberculosis 189000.0 2 PMID:19543810;PMID:26921318 -4.1.1.20 * oryza sativa 53200.0 1 * -4.1.1.20 * vibrio cholerae serotype o1 92000.0 1 PMID:26921318 -4.1.1.21 * bacillus subtilis 42150.0 2 PMID:3036807 -4.1.1.21 * escherichia coli 39000.0 2 PMID:1534690 -4.1.1.21 * ovis aries 420000.0 3 PMID:1781372 -4.1.1.21 * treponema denticola 184000.0 3 PMID:21548610 -4.1.1.21 * trichoplusia ni 360000.0 2 PMID:23553965 -4.1.1.21 * zygosaccharomyces rouxii 62200.0 1 PMID:10509021 -4.1.1.22 * clostridium perfringens 27000.0 2 PMID:6294108 -4.1.1.22 * homo sapiens 74000.0 4 PMID:24941343;PMID:27769832;PMID:8750788 -4.1.1.22 * klebsiella aerogenes 50000.0 1 PMID:3114230 -4.1.1.22 * lactobacillus sp. 208000.0 8 PMID:3517561;PMID:37890 -4.1.1.22 * morganella morganii 170000.0 3 PMID:3702683;PMID:3997848 -4.1.1.22 * mus musculus 115000.0 9 PMID:1540215;PMID:17360717;PMID:2118138;PMID:21440039;PMID:3718471;PMID:6425286 -4.1.1.22 * oenococcus oeni 25380.0 2 PMID:9633629 -4.1.1.22 * raoultella planticola 42500.0 2 PMID:3114230 -4.1.1.22 * rattus norvegicus 210000.0 8 PMID:15316670;PMID:1540215;PMID:2118138;PMID:21440039;PMID:6425286;PMID:6778871;PMID:7138509 -4.1.1.22 * staphylococcus capitis 34200.0 1 PMID:17887985 -4.1.1.22 * staphylococcus epidermidis 121000.0 1 * -4.1.1.22 * streptococcus thermophilus 37000.0 3 PMID:21208300 -4.1.1.22 * tetragenococcus muriaticus 258000.0 3 PMID:12010554 -4.1.1.23 * escherichia coli 54000.0 2 PMID:6355062 -4.1.1.23 * homo sapiens 250000.0 4 PMID:1165245;PMID:18181562 -4.1.1.23 * lathyrus oleraceus 62000.0 1 * -4.1.1.23 * methanothermobacter thermautotrophicus 27340.0 1 PMID:18181562 -4.1.1.23 * mus musculus 115000.0 1 PMID:4355548 -4.1.1.23 * myrothecium gramineum 30000.0 1 PMID:16907730 -4.1.1.23 * paracoccidioides brasiliensis 31100.0 1 PMID:16034822 -4.1.1.23 * plasmodium falciparum 158000.0 10 PMID:15147974;PMID:16754976;PMID:17981823;PMID:18181562;PMID:18303855;PMID:24507637;PMID:28389349 -4.1.1.23 * pseudomonas aeruginosa 46000.0 1 PMID:7765522 -4.1.1.23 * saccharomyces cerevisiae 64000.0 5 PMID:10446147;PMID:2061334;PMID:357908 -4.1.1.23 * sulfolobus acidocaldarius 46000.0 2 * -4.1.1.23 * thermoplasma acidophilum 22800.0 1 PMID:10973825 -4.1.1.25 * arabidopsis thaliana 232000.0 2 PMID:19450582 -4.1.1.25 * enterococcus faecalis 70053.0 2 PMID:19405032;PMID:24680070 -4.1.1.25 * enterococcus faecium 70300.0 1 PMID:24680070 -4.1.1.25 * eschscholzia californica 112000.0 5 PMID:10872203;PMID:16666277;PMID:16666278 -4.1.1.25 * levilactobacillus brevis 140000.0 5 PMID:11167003;PMID:12052555;PMID:24211777 -4.1.1.25 * locusta migratoria 370000.0 1 PMID:11918967 -4.1.1.25 * methanocaldococcus jannaschii 90000.0 2 PMID:15715981 -4.1.1.25 * pyrococcus furiosus 41000.0 2 * -4.1.1.25 * rhodiola sachalinensis 56800.0 1 PMID:21538102 -4.1.1.25 * thalictrum rugosum 112000.0 5 PMID:10872203;PMID:16666277;PMID:16666278 -4.1.1.28 * azumapecten farreri 63380.0 1 PMID:21533240 -4.1.1.28 * bacillus atrophaeus 58000.0 2 PMID:23628927 -4.1.1.28 * bos taurus 106000.0 4 PMID:12718431;PMID:2115615;PMID:2374548;PMID:3415655;PMID:3584092;PMID:3600369;PMID:8653578 -4.1.1.28 * calliphora vicina 90000.0 3 PMID:1137393 -4.1.1.28 * catharanthus roseus 115000.0 2 PMID:10872203 -4.1.1.28 * ceratitis capitata 100000.0 3 PMID:12718431;PMID:2374548;PMID:3415655;PMID:3584092;PMID:3600369;PMID:8653578 -4.1.1.28 * dirofilaria immitis 48000.0 1 PMID:11258661 -4.1.1.28 * drosophila melanogaster 113000.0 3 * -4.1.1.28 * homo sapiens 100000.0 12 PMID:12718431;PMID:16517981;PMID:19041269;PMID:19800137;PMID:20403077;PMID:20535562;PMID:21479916;PMID:2374548;PMID:3415655;PMID:3584092;PMID:3600369;PMID:8653578 -4.1.1.28 * locusta migratoria 112000.0 1 PMID:11918967 -4.1.1.28 * micrococcus percitreus 105000.0 3 PMID:4441405 -4.1.1.28 * mitragyna speciosa 57000.0 2 * -4.1.1.28 * mus musculus 54000.0 3 PMID:10785380;PMID:11513473;PMID:18310457;PMID:20456015 -4.1.1.28 * penicillium raistrickii 125000.0 1 * -4.1.1.28 * rattus norvegicus 100000.0 6 PMID:10844518;PMID:12718431;PMID:2374548;PMID:3119338;PMID:3415655;PMID:3584092;PMID:3600369;PMID:8653578 -4.1.1.28 * sus scrofa 103000.0 4 PMID:12718431;PMID:19857468;PMID:2374548;PMID:2508758;PMID:3415655;PMID:3584092;PMID:3600369;PMID:8653578 -4.1.1.28 * tenebrio molitor 50000.0 1 PMID:10785380;PMID:11513473 -4.1.1.28 * vitis vinifera x vitis riparia 54000.0 1 PMID:21789483 -4.1.1.29 * cyprinus carpio 82100.0 4 PMID:19633968 -4.1.1.29 * mus musculus 53000.0 1 PMID:16252094 -4.1.1.29 * rattus norvegicus 105000.0 10 PMID:17634260;PMID:2303816;PMID:236774;PMID:3584115 -4.1.1.29 * sus scrofa 90000.0 3 PMID:11725125 -4.1.1.29 * tribolium castaneum 109000.0 1 PMID:31696283 -4.1.1.31 * acetobacter aceti 400000.0 1 * -4.1.1.31 * amaranthus viridis 400000.0 2 PMID:1898033;PMID:24232027;PMID:8902615 -4.1.1.31 * ancylobacter novellus 360000.0 2 PMID:1416912 -4.1.1.31 * arabidopsis thaliana 430000.0 6 PMID:16283377;PMID:19923749;PMID:23407057 -4.1.1.31 * brassica napus 440000.0 2 PMID:10880970 -4.1.1.31 * chlamydomonas reinhardtii 669000.0 5 PMID:17888908;PMID:9512480 -4.1.1.31 * cicer arietinum 200000.0 2 PMID:16664628 -4.1.1.31 * coccochloris peniocystis 560000.0 1 PMID:3093461;PMID:4212347 -4.1.1.31 * crassula argentea 400000.0 2 PMID:1898033;PMID:24232027;PMID:8902615 -4.1.1.31 * echinochloa crus-galli 400000.0 2 PMID:1898033;PMID:24232027;PMID:8902615 -4.1.1.31 * escherichia coli 400000.0 3 PMID:4560418 -4.1.1.31 * fagus sylvatica 110000.0 1 PMID:16624802;PMID:17997763 -4.1.1.31 * hakea prostrata 430000.0 4 PMID:19923749;PMID:23407057 -4.1.1.31 * hyphomicrobium methylovorum 389000.0 2 * -4.1.1.31 * kalanchoe fedtschenkoi 500000.0 6 PMID:1022554;PMID:3800979;PMID:743204 -4.1.1.31 * lilium longiflorum 900000.0 1 PMID:20836890 -4.1.1.31 * medicago sativa 97000.0 1 PMID:16663590 -4.1.1.31 * megathyrsus maximus 70680.0 1 PMID:17337522 -4.1.1.31 * methanothermobacter thermautotrophicus 277000.0 2 PMID:15262949 -4.1.1.31 * methanothermus sociabilis 240000.0 2 PMID:8772193 -4.1.1.31 * molinema dessetae 64000.0 1 PMID:8479801 -4.1.1.31 * monoraphidium minutum 1590000.0 18 PMID:11278626;PMID:12154141 -4.1.1.31 * nicotiana tabacum 110000.0 2 PMID:19090725;PMID:8280159;PMID:8988646 -4.1.1.31 * phaeodactylum tricornutum 117000.0 1 PMID:24835101 -4.1.1.31 * photobacterium profundum 99000.0 1 PMID:23719931 -4.1.1.31 * picosynechococcus sp. pcc 7002 924000.0 3 PMID:32107404 -4.1.1.31 * plasmodium berghei 280000.0 1 PMID:4621631 -4.1.1.31 * rhodopseudomonas sp. 400000.0 2 PMID:24232027;PMID:8902615 -4.1.1.31 * ricinus communis 910000.0 18 PMID:12519778;PMID:16169958;PMID:19605358;PMID:20950272;PMID:21841182;PMID:22404138;PMID:22569262 -4.1.1.31 * saccharolobus solfataricus 58772.0 1 PMID:15516590 -4.1.1.31 * sorghum bicolor 110000.0 3 PMID:16624802;PMID:17997763;PMID:8280159;PMID:8988646 -4.1.1.31 * spinacia oleracea 560000.0 2 PMID:3093461;PMID:4212347 -4.1.1.31 * streptomyces coelicolor 43000.0 1 PMID:8328954 -4.1.1.31 * sulfolobus acidocaldarius 260000.0 2 PMID:8772193 -4.1.1.31 * synechocystis sp. pcc 6803 233800.0 1 PMID:32274833 -4.1.1.31 * thermostichus vulcanus 570000.0 2 PMID:11867695 -4.1.1.31 * thermus sp. 400000.0 2 PMID:1898033;PMID:24232027;PMID:8902615 -4.1.1.31 * umbilicus rupestris 185300.0 1 PMID:6712622 -4.1.1.31 * vicia faba 450000.0 2 * -4.1.1.31 * zea mays 420000.0 9 PMID:2775222;PMID:3700388;PMID:883835 -4.1.1.32 * aquarana catesbeiana 75000.0 5 PMID:314446;PMID:6970195 -4.1.1.32 * ascaris suum 83000.0 1 PMID:3759946 -4.1.1.32 * corynebacterium glutamicum 67540.0 2 PMID:14550651 -4.1.1.32 * euglena gracilis 761000.0 4 PMID:16665930 -4.1.1.32 * gallus gallus 75400.0 8 PMID:10684618;PMID:11551200;PMID:16819824;PMID:3782066;PMID:4828524;PMID:7068603 -4.1.1.32 * homo sapiens 69448.0 2 PMID:11851336;PMID:19021757 -4.1.1.32 * magallana gigas 69250.0 2 PMID:17486628 -4.1.1.32 * modiolus demissus 70000.0 1 * -4.1.1.32 * mycobacterium tuberculosis 72000.0 1 PMID:16691317 -4.1.1.32 * mycolicibacterium smegmatis 83200.0 3 PMID:11278451;PMID:17015450 -4.1.1.32 * oryctolagus cuniculus 65000.0 2 PMID:3334872 -4.1.1.32 * ovis aries 50000.0 1 PMID:5047708 -4.1.1.32 * perumytilus purpuratus 85000.0 2 * -4.1.1.32 * raillietina echinobothrida 65000.0 1 PMID:22906884 -4.1.1.32 * rattus norvegicus 74000.0 2 PMID:728402 -4.1.1.32 * saccharomyces cerevisiae 80000.0 2 PMID:7947744 -4.1.1.32 * squalus acanthias 71000.0 2 PMID:2369129 -4.1.1.32 * streptococcus equinus 62254.0 1 PMID:20513959 -4.1.1.32 * thermococcus kodakarensis 284000.0 4 PMID:15231795 -4.1.1.33 * bacopa monnieri 94000.0 2 PMID:26027607 -4.1.1.33 * catharanthus roseus 46600.0 2 PMID:21655959 -4.1.1.33 * cavia porcellus 46000.0 1 PMID:19652394 -4.1.1.33 * gallus gallus 87600.0 3 PMID:6814481 -4.1.1.33 * ganoderma lucidum 43270.0 1 PMID:22203490 -4.1.1.33 * ginkgo biloba 48000.0 1 * -4.1.1.33 * homo sapiens 44000.0 1 PMID:18823933;PMID:20971863 -4.1.1.33 * mus musculus 100000.0 2 PMID:11913522;PMID:2825791;PMID:8744421 -4.1.1.33 * rattus norvegicus 100000.0 5 PMID:11725954;PMID:11913522;PMID:8744421;PMID:9348097 -4.1.1.33 * saccharolobus solfataricus 52000.0 5 PMID:23378249;PMID:26303832 -4.1.1.33 * saccharomyces cerevisiae 107000.0 5 PMID:15169949;PMID:17583736;PMID:18823933;PMID:20971863 -4.1.1.33 * staphylococcus aureus 36800.0 1 PMID:17583736 -4.1.1.33 * staphylococcus epidermidis 36000.0 1 PMID:21561869 -4.1.1.33 * streptococcus pneumoniae 35500.0 1 PMID:20737255 -4.1.1.33 * sus scrofa 88000.0 2 PMID:11913522;PMID:2825791 -4.1.1.33 * trypanosoma brucei 42200.0 2 PMID:16511101;PMID:17583736 -4.1.1.35 * arabidopsis thaliana 48300.0 2 PMID:12481102 -4.1.1.35 * cryptococcus neoformans 47000.0 2 PMID:11593010 -4.1.1.35 * gossypium hirsutum 66700.0 6 * -4.1.1.35 * lathyrus oleraceus 250000.0 3 PMID:12461125 -4.1.1.35 * micromonospora echinospora subsp. calichensis 33000.0 1 PMID:19290519 -4.1.1.35 * nicotiana tabacum 220000.0 4 PMID:12453569;PMID:12815035;PMID:15821883;PMID:17920089 -4.1.1.35 * oryza sativa 40000.0 1 PMID:12815035;PMID:17920089 -4.1.1.35 * populus tomentosa 49700.0 7 PMID:23613749 -4.1.1.35 * rattus norvegicus 47000.0 1 PMID:11877387 -4.1.1.35 * triticum aestivum 210000.0 1 PMID:914860 -4.1.1.36 * escherichia coli 270000.0 5 PMID:11358972;PMID:12565925;PMID:3307915 -4.1.1.36 * methanocaldococcus jannaschii 242000.0 2 PMID:16371361 -4.1.1.36 * nicotiana tabacum 23000.0 2 PMID:14739262 -4.1.1.37 * bacillus subtilis 83590.0 4 PMID:17122346 -4.1.1.37 * cereibacter sphaeroides 41000.0 2 PMID:8352737 -4.1.1.37 * euglena gracilis 54000.0 1 PMID:2492941 -4.1.1.37 * gallus gallus 79000.0 2 PMID:3702738;PMID:6403526 -4.1.1.37 * homo sapiens 86000.0 19 PMID:1582524;PMID:18004775;PMID:19041871;PMID:19362562;PMID:19419417;PMID:3619926;PMID:6626181;PMID:6822570;PMID:7592567;PMID:9251000 -4.1.1.37 * neohelice granulata 48000.0 1 PMID:12381387 -4.1.1.37 * nicotiana tabacum 82000.0 2 PMID:11679753 -4.1.1.37 * parachlorella kessleri 90000.0 2 PMID:17496980 -4.1.1.37 * plasmodium falciparum 43000.0 1 PMID:19041871 -4.1.1.37 * rattus norvegicus 65000.0 1 PMID:11378443 -4.1.1.37 * rhodopseudomonas palustris 46000.0 1 PMID:2180703 -4.1.1.37 * saccharomyces cerevisiae 46000.0 2 PMID:2180703 -4.1.1.37 * synechococcus elongatus 64000.0 1 PMID:18460784 -4.1.1.38 * entamoeba histolytica 440000.0 6 PMID:26269598 -4.1.1.38 * propionibacterium freudenreichii subsp. shermanii 430000.0 5 PMID:200082;PMID:4288896;PMID:4846752 -4.1.1.38 * selenomonas ruminantium 60000.0 1 PMID:11238975 -4.1.1.39 * acidithiobacillus ferrooxidans 570000.0 3 * -4.1.1.39 * acidovorax facilis 551000.0 1 PMID:805894 -4.1.1.39 * acinetobacter sp. 520000.0 3 PMID:9264026 -4.1.1.39 * allochromatium vinosum 530000.0 1 PMID:2211708 -4.1.1.39 * alviniconcha hessleri 55460.0 3 PMID:8180629 -4.1.1.39 * amorphochlora amoebiformis 47200.0 2 PMID:21049565 -4.1.1.39 * amphidinium carterae 560000.0 3 PMID:10480884;PMID:12221984 -4.1.1.39 * anabaena sp. 560000.0 3 PMID:10480884;PMID:12221984 -4.1.1.39 * aphanothece halophytica 237000.0 2 * -4.1.1.39 * arabidopsis sp. 55000.0 2 PMID:10480884;PMID:12221984 -4.1.1.39 * arabidopsis thaliana 560000.0 3 PMID:10480884;PMID:12221984 -4.1.1.39 * archaeoglobus fulgidus 48500.0 1 PMID:17074752 -4.1.1.39 * bacteria 55000.0 2 PMID:18417482 -4.1.1.39 * bangia fuscopurpurea 55000.0 1 PMID:21283730 -4.1.1.39 * bradyrhizobium japonicum 55000.0 2 * -4.1.1.39 * brassica juncea 48850.0 2 PMID:19655309 -4.1.1.39 * chlamydomonas reinhardtii 560000.0 4 PMID:10480884;PMID:12049611;PMID:12221984 -4.1.1.39 * chlorella sorokiniana 562000.0 2 PMID:16664495 -4.1.1.39 * chlorobaculum tepidum 560000.0 3 PMID:10480884;PMID:12221984 -4.1.1.39 * citrus sinensis 524000.0 3 * -4.1.1.39 * cupriavidus necator 560000.0 7 PMID:1015944;PMID:10480884;PMID:12221984;PMID:805894 -4.1.1.39 * cyanidium caldarium 55000.0 2 PMID:113034 -4.1.1.39 * cyanobacterium 55000.0 2 PMID:18417482 -4.1.1.39 * cyanophora paradoxa 545000.0 1 * -4.1.1.39 * cylindrotheca sp. 560000.0 3 PMID:10480884;PMID:12221984 -4.1.1.39 * embryophyta 55000.0 2 PMID:18417482 -4.1.1.39 * flaveria bidentis 560000.0 3 PMID:10480884;PMID:12221984 -4.1.1.39 * glycine max 55000.0 2 PMID:10480884;PMID:12221984 -4.1.1.39 * haloferax mediterranei 500000.0 3 PMID:8174567 -4.1.1.39 * halothiobacillus neapolitanus 52000.0 2 PMID:18258595 -4.1.1.39 * helianthus annuus 560000.0 3 PMID:10480884;PMID:12221984 -4.1.1.39 * hordeum vulgare 55000.0 4 PMID:10480884;PMID:12221984;PMID:3857021 -4.1.1.39 * hydrogenophaga pseudoflava 505000.0 3 PMID:9264026 -4.1.1.39 * hydrogenovibrio marinus 110000.0 2 PMID:8319883 -4.1.1.39 * kalanchoe pinnata 55000.0 5 PMID:18445036 -4.1.1.39 * lathyrus oleraceus 55000.0 2 PMID:10480884;PMID:12221984 -4.1.1.39 * lolium perenne 54500.0 2 PMID:7305349 -4.1.1.39 * medicago sativa 560000.0 2 PMID:7362838 -4.1.1.39 * methanocaldococcus jannaschii 105000.0 4 PMID:10049390;PMID:12730164 -4.1.1.39 * methanococcoides burtonii 105700.0 3 PMID:19837658 -4.1.1.39 * mycobacterium sp. 52000.0 4 PMID:19135529 -4.1.1.39 * nicotiana tabacum 560000.0 7 PMID:10480884;PMID:12221984;PMID:3857021 -4.1.1.39 * nitrobacter winogradskyi 500000.0 4 * -4.1.1.39 * nitrosomonas sp. 460000.0 3 PMID:16232884 -4.1.1.39 * olisthodiscus luteus 588000.0 3 PMID:16665466 -4.1.1.39 * oryza sativa 55000.0 8 PMID:12221984;PMID:18755596;PMID:22609438 -4.1.1.39 * paracoccus denitrificans 513000.0 3 * -4.1.1.39 * petunia sp. 55000.0 2 PMID:10480884;PMID:12221984 -4.1.1.39 * pyropia haitanensis 55000.0 1 PMID:21283730 -4.1.1.39 * pyropia yezoensis 55000.0 1 PMID:21283730 -4.1.1.39 * rhodomicrobium vannielii 430000.0 3 * -4.1.1.39 * rhodospirillum rubrum 114000.0 3 PMID:33152;PMID:805894 -4.1.1.39 * saccharina japonica 55000.0 1 PMID:21283730 -4.1.1.39 * secale cereale x triticum aestivum 540000.0 3 PMID:7927432 -4.1.1.39 * solanum lycopersicum 560000.0 5 PMID:10480884;PMID:12221984 -4.1.1.39 * solanum tuberosum 55000.0 2 PMID:10480884;PMID:12221984 -4.1.1.39 * spinacia oleracea 560000.0 7 PMID:10480884;PMID:12221984;PMID:16469293;PMID:18709490 -4.1.1.39 * sulfobacillus acidophilus 53000.0 1 PMID:17600067 -4.1.1.39 * sulfobacillus thermosulfidooxidans 54000.0 1 PMID:17600067 -4.1.1.39 * symphytum sp. 501600.0 3 * -4.1.1.39 * synechococcus elongatus pcc 7942 = fachb-805 560000.0 3 PMID:10480884;PMID:12221984 -4.1.1.39 * synechococcus sp. 560000.0 4 PMID:10480884;PMID:12221984;PMID:12899828 -4.1.1.39 * thermochromatium tepidum 500000.0 3 PMID:2507319 -4.1.1.39 * thermococcus kodakarensis 50000.0 2 PMID:20926376;PMID:9988755 -4.1.1.39 * thermosynechococcus vestitus 53000.0 2 PMID:17922215 -4.1.1.39 * thiobacillus denitrificans 500000.0 2 PMID:8550452 -4.1.1.39 * trichormus variabilis 560000.0 3 PMID:10480884;PMID:12221984 -4.1.1.39 * triticum aestivum 55000.0 2 PMID:10480884;PMID:12221984 -4.1.1.39 * vigna unguiculata 55000.0 1 * -4.1.1.39 * zea mays 560000.0 6 PMID:10480884;PMID:12221984 -4.1.1.4 * chromobacterium violaceum 365000.0 1 PMID:19458715 -4.1.1.4 * clostridium acetobutylicum 365000.0 5 PMID:19458715;PMID:2254264;PMID:5657853 -4.1.1.4 * paenibacillus polymyxa 280000.0 2 * -4.1.1.43 * achromobacter eurydice 150000.0 3 * -4.1.1.43 * acinetobacter calcoaceticus 235000.0 2 * -4.1.1.43 * azospirillum brasilense 240600.0 3 PMID:17403037;PMID:17766418 -4.1.1.43 * saccharomyces cerevisiae 57000.0 1 PMID:21501384 -4.1.1.44 * acinetobacter calcoaceticus 85500.0 2 PMID:6783616;PMID:7391024 -4.1.1.44 * pseudomonas putida 93000.0 3 PMID:6783616;PMID:7391024 -4.1.1.44 * saccharolobus solfataricus 15950.0 1 PMID:19923750 -4.1.1.45 * homo sapiens 50000.0 2 PMID:17288562 -4.1.1.45 * pseudomonas fluorescens 121000.0 5 PMID:11802786;PMID:12620844;PMID:16131206;PMID:31189654 -4.1.1.45 * rattus norvegicus 41000.0 3 PMID:10721108;PMID:11802786;PMID:16131206 -4.1.1.45 * sus scrofa 58000.0 2 PMID:8866254 -4.1.1.46 * aspergillus niger 150000.0 3 PMID:3593354 -4.1.1.46 * aspergillus oryzae 130000.0 2 PMID:8620029 -4.1.1.46 * cutaneotrichosporon cutaneum 66100.0 2 PMID:7194334 -4.1.1.46 * fusarium odoratissimum nrrl 54006 143600.0 1 PMID:29602385 -4.1.1.47 * escherichia coli 145000.0 4 PMID:1107332;PMID:22104170;PMID:8440684 -4.1.1.48 * aeromonas caviae 45000.0 1 PMID:1116988 -4.1.1.48 * bacillus subtilis 31000.0 2 PMID:110789 -4.1.1.48 * chromobacterium violaceum 22000.0 1 PMID:5669904 -4.1.1.48 * citrobacter freundii 47000.0 1 PMID:1116988 -4.1.1.48 * enterobacter cloacae 47000.0 1 PMID:1116988 -4.1.1.48 * enterobacter cloacae subsp. dissolvens 47000.0 1 PMID:1116988 -4.1.1.48 * enterobacter liquefaciens 45000.0 1 PMID:1116988 -4.1.1.48 * escherichia coli 45000.0 1 PMID:4919415 -4.1.1.48 * euglena gracilis 325000.0 2 PMID:401810 -4.1.1.48 * hafnia alvei 48000.0 1 PMID:1116988;PMID:4559725 -4.1.1.48 * klebsiella aerogenes 45000.0 2 PMID:4919415 -4.1.1.48 * morganella morganii 53000.0 1 PMID:1116988 -4.1.1.48 * mycobacterium tuberculosis 30000.0 2 PMID:19364491 -4.1.1.48 * neurospora crassa 340000.0 3 PMID:125757 -4.1.1.48 * pectobacterium carotovorum 48000.0 1 PMID:1116988;PMID:4559725 -4.1.1.48 * proteus vulgaris 53000.0 1 PMID:1116988 -4.1.1.48 * pseudomonas aeruginosa 31000.0 1 PMID:22555873 -4.1.1.48 * pseudomonas putida 32000.0 1 PMID:5636809 -4.1.1.48 * pyrococcus furiosus 25000.0 1 PMID:30264228 -4.1.1.48 * saccharolobus solfataricus 28600.0 5 PMID:16342933;PMID:7947963;PMID:8747456 -4.1.1.48 * salmonella enterica subsp. enterica serovar typhimurium 45000.0 1 PMID:4919415 -4.1.1.48 * serratia marcescens 48000.0 2 PMID:1116988;PMID:4559725 -4.1.1.48 * serratia rubidaea 45000.0 1 PMID:1116988 -4.1.1.48 * thermotoga maritima 47100.0 5 PMID:11265469;PMID:16342933 -4.1.1.49 * anaerobiospirillum succiniciproducens 58000.0 2 PMID:8436945 -4.1.1.49 * arabidopsis thaliana 440000.0 2 PMID:31548269 -4.1.1.49 * cucumis sativus 400000.0 3 PMID:11354601;PMID:7698356 -4.1.1.49 * escherichia coli 65000.0 2 PMID:175900 -4.1.1.49 * leishmania major 103000.0 1 PMID:26271440 -4.1.1.49 * leishmania mexicana mexicana 65100.0 2 PMID:3970941 -4.1.1.49 * plasmodium falciparum 66200.0 1 PMID:10779599 -4.1.1.49 * ruminococcus albus 59430.0 1 PMID:19194751 -4.1.1.49 * saccharomyces cerevisiae 284000.0 7 PMID:11943595;PMID:17195942;PMID:18346928;PMID:20524049;PMID:21031264;PMID:5416663 -4.1.1.49 * salinivibrio costicola 60000.0 2 PMID:2775185 -4.1.1.49 * selenomonas ruminantium 60000.0 3 PMID:11238975 -4.1.1.49 * skeletonema costatum 56000.0 1 * -4.1.1.49 * solanum lycopersicum 74000.0 2 PMID:11669575 -4.1.1.49 * trypanosoma brucei 115000.0 2 PMID:7766679 -4.1.1.49 * trypanosoma cruzi 82000.0 3 PMID:3310897;PMID:8294043 -4.1.1.49 * zea mays 64000.0 1 PMID:11354601 -4.1.1.5 * bacillus spizizenii 61000.0 1 * -4.1.1.5 * brevibacillus brevis 70000.0 2 * -4.1.1.5 * exiguobacterium acetylicum 62000.0 2 * -4.1.1.5 * klebsiella aerogenes 73000.0 1 PMID:236481 -4.1.1.5 * klebsiella pneumoniae 57000.0 1 PMID:30580999 -4.1.1.5 * lacticaseibacillus casei 48000.0 2 * -4.1.1.5 * lactococcus lactis 150000.0 2 PMID:8076701 -4.1.1.5 * leuconostoc lactis 100000.0 2 PMID:11164316 -4.1.1.50 * acanthamoeba castellanii 88000.0 3 PMID:8216217 -4.1.1.50 * bacillus subtilis 14000.0 1 PMID:20095968 -4.1.1.50 * brassica juncea 40600.0 4 * -4.1.1.50 * caenorhabditis elegans 32000.0 2 PMID:9841864 -4.1.1.50 * catharanthus roseus 39000.0 1 PMID:20095968 -4.1.1.50 * clostridium acetobutylicum 32000.0 1 PMID:20095968 -4.1.1.50 * escherichia coli 136000.0 7 PMID:20095968;PMID:3546296;PMID:6353153;PMID:6364703 -4.1.1.50 * glycine max 66000.0 1 PMID:1764068 -4.1.1.50 * homo sapiens 39600.0 5 PMID:10029540;PMID:17593800;PMID:20095968 -4.1.1.50 * leishmania donovani 68000.0 2 PMID:117828;PMID:25511700;PMID:6621387;PMID:7104315 -4.1.1.50 * leishmania infantum 46000.0 1 PMID:12049458 -4.1.1.50 * methanocaldococcus jannaschii 35000.0 7 PMID:11073910;PMID:20095968 -4.1.1.50 * mus musculus 74000.0 3 PMID:117828;PMID:25511700;PMID:6621387;PMID:7104315 -4.1.1.50 * olea europaea 39086.0 1 PMID:20532909 -4.1.1.50 * plasmodium falciparum 70000.0 2 PMID:21803076 -4.1.1.50 * rattus norvegicus 68000.0 8 PMID:117828;PMID:25511700;PMID:3902085;PMID:4429660;PMID:5059883;PMID:6621387;PMID:7104315 -4.1.1.50 * saccharolobus solfataricus 36000.0 5 PMID:1649051;PMID:18650422 -4.1.1.50 * saccharomyces cerevisiae 88000.0 3 PMID:20095968;PMID:6312267;PMID:6364703 -4.1.1.50 * solanum tuberosum 40000.0 1 PMID:20095968 -4.1.1.50 * streptomyces griseochromogenes 40200.0 1 PMID:23874663 -4.1.1.50 * thermotoga maritima 15000.0 1 PMID:20095968 -4.1.1.50 * trypanosoma brucei 44000.0 1 PMID:20095968 -4.1.1.50 * trypanosoma cruzi 70000.0 4 PMID:10413038;PMID:20095968 -4.1.1.50 * xenopus laevis 37000.0 1 PMID:20013010 -4.1.1.50 * zea mays 25000.0 1 PMID:16661582 -4.1.1.51 * mesorhizobium loti 26000.0 1 PMID:17973403 -4.1.1.52 * aspergillus clavatus 43000.0 1 PMID:24334092 -4.1.1.52 * penicillium griseofulvum 70000.0 2 PMID:237216;PMID:5354271 -4.1.1.55 * comamonas testosteroni 150000.0 2 PMID:29563 -4.1.1.55 * pseudomonas fluorescens 420000.0 2 PMID:3920963 -4.1.1.57 * crypthecodinium cohnii 204000.0 2 * -4.1.1.57 * dryopteris filix-mas 100000.0 2 PMID:2271523;PMID:2271525 -4.1.1.57 * streptomyces sp. 130000.0 3 PMID:2271523;PMID:2271525 -4.1.1.57 * streptomyces sp. 590 ki-2014 110000.0 1 PMID:28003434 -4.1.1.58 * lasallia pustulata 90000.0 2 PMID:5128738 -4.1.1.59 * blastobotrys adeninivorans 27100.0 1 PMID:28966611 -4.1.1.59 * pantoea agglomerans 320000.0 2 PMID:9835557 -4.1.1.6 * aspergillus terreus 55000.0 3 PMID:18584171;PMID:23420787 -4.1.1.6 * homo sapiens 55000.0 1 PMID:23610393 -4.1.1.61 * bacillus subtilis 8569.0 1 PMID:18388975 -4.1.1.61 * chlamydia pneumoniae 64000.0 1 PMID:17211544 -4.1.1.61 * enterobacter cloacae 372000.0 3 PMID:16758158 -4.1.1.61 * pseudomonas sp. 280000.0 1 PMID:1592817 -4.1.1.61 * sedimentibacter hydroxybenzoicus 350000.0 2 PMID:7744052 -4.1.1.63 * sedimentibacter hydroxybenzoicus 270000.0 2 PMID:8655551 -4.1.1.64 * burkholderia cepacia 188000.0 4 PMID:16290167;PMID:5140194;PMID:7799433 -4.1.1.64 * fusarium solani 166000.0 2 * -4.1.1.65 * avena sativa 35000.0 1 PMID:16762557 -4.1.1.65 * cricetulus griseus 44172.0 1 PMID:9211308 -4.1.1.65 * escherichia coli 400000.0 10 PMID:1495415;PMID:3042771;PMID:4598120;PMID:7011377 -4.1.1.65 * mus musculus 65000.0 1 * -4.1.1.65 * plasmodium falciparum 42600.0 2 PMID:14651609 -4.1.1.65 * plasmodium knowlesi 43000.0 2 PMID:22057268 -4.1.1.65 * rattus norvegicus 200000.0 2 PMID:1495416;PMID:8132055 -4.1.1.65 * saccharomyces cerevisiae 118868.0 5 PMID:22984266;PMID:9211308 -4.1.1.65 * toxoplasma gondii 108000.0 2 PMID:22563079;PMID:24429285 -4.1.1.68 * escherichia coli 50000.0 4 PMID:8223600 -4.1.1.7 * pseudomonas putida 248000.0 6 PMID:18239944;PMID:23728901;PMID:3179267;PMID:7663351;PMID:9655924 -4.1.1.7 * stutzerimonas stutzeri 220000.0 2 PMID:17916405 -4.1.1.71 * euglena gracilis 250000.0 2 PMID:1910306 -4.1.1.71 * oenococcus oeni 70000.0 2 * -4.1.1.71 * picosynechococcus sp. pcc 7002 247000.0 1 PMID:29574001 -4.1.1.72 * bacillus subtilis 175000.0 3 PMID:3142877 -4.1.1.72 * bos taurus 160000.0 3 PMID:1352285 -4.1.1.72 * homo sapiens 171000.0 6 PMID:10187829;PMID:1352285 -4.1.1.72 * lactococcus lactis 146000.0 6 PMID:15640202;PMID:23826991 -4.1.1.72 * lactococcus lactis subsp. lactis 240000.0 2 PMID:15358422 -4.1.1.72 * mycobacterium tuberculosis 59780.0 1 PMID:18086676 -4.1.1.72 * psychrobacter arcticus 55000.0 1 PMID:23826991 -4.1.1.72 * psychrobacter cryohalolentis 55000.0 1 PMID:23826991 -4.1.1.72 * thermoplasma acidophilum 165000.0 1 PMID:15556640 -4.1.1.73 * pseudomonas sp. 148000.0 2 PMID:1778975 -4.1.1.74 * enterobacter cloacae 245000.0 4 PMID:12752452;PMID:1639814;PMID:21314613;PMID:24043123;PMID:7766676 -4.1.1.74 * methylorubrum extorquens 245000.0 2 PMID:12752452;PMID:1639814;PMID:21314613;PMID:7766676 -4.1.1.74 * paenibacillus polymyxa e681 63380.0 1 PMID:18667851 -4.1.1.74 * sulfolobus sp. 280000.0 4 PMID:11801253 -4.1.1.76 * achromobacter sp. 24740.0 2 PMID:18023797;PMID:18283449 -4.1.1.76 * bordetella bronchiseptica 26100.0 8 PMID:1369144;PMID:1459132;PMID:18258259;PMID:18607088 -4.1.1.76 * enterobacter cloacae 24000.0 1 PMID:18023797;PMID:18283449 -4.1.1.77 * bordetella sp. 29000.0 1 PMID:17090920 -4.1.1.77 * geobacillus stearothermophilus 28900.0 1 PMID:19014555 -4.1.1.77 * pseudomonas putida 30000.0 2 PMID:27082660 -4.1.1.79 * methanocaldococcus jannaschii 210000.0 3 PMID:10940029 -4.1.1.79 * methanosarcina acetivorans 103000.0 3 PMID:19761441 -4.1.1.79 * roseovarius nubinhibens 235000.0 1 PMID:19581363 -4.1.1.8 * arabidopsis thaliana 123000.0 1 PMID:33806862 -4.1.1.8 * bifidobacterium animalis subsp. lactis 63710.0 1 PMID:20601517 -4.1.1.8 * enterococcus faecalis 65000.0 1 PMID:10832966 -4.1.1.8 * escherichia coli 230000.0 2 PMID:20553497 -4.1.1.8 * lactobacillus acidophilus 65000.0 1 PMID:17953571 -4.1.1.8 * oxalobacter formigenes 260000.0 3 PMID:16216870;PMID:2708315 -4.1.1.80 * berberis stolonifera 30000.0 1 * -4.1.1.81 * salmonella enterica 40800.0 1 PMID:11939774 -4.1.1.81 * salmonella enterica subsp. enterica serovar typhimurium 40800.0 1 PMID:9446573 -4.1.1.82 * bacteroides fragilis 120000.0 3 PMID:12904299 -4.1.1.82 * streptomyces hygroscopicus 135000.0 2 PMID:9439692 -4.1.1.82 * streptomyces viridochromogenes 72100.0 4 PMID:9673017 -4.1.1.83 * clostridioides difficile 460000.0 7 PMID:11231288;PMID:15153112;PMID:16878993 -4.1.1.83 * clostridium scatologenes 440000.0 5 PMID:16878993;PMID:21823587;PMID:23716017 -4.1.1.84 * homo sapiens 13000.0 1 PMID:9480844 -4.1.1.84 * rattus norvegicus 37000.0 4 PMID:18930782;PMID:8267597;PMID:9285056 -4.1.1.86 * acinetobacter baumannii 53000.0 4 PMID:7550102;PMID:7813892;PMID:8772175;PMID:9260954 -4.1.1.86 * acinetobacter calcoaceticus 108000.0 3 PMID:1512577;PMID:7550102 -4.1.1.86 * klebsiella aerogenes 100000.0 3 PMID:10823682;PMID:8913500 -4.1.1.86 * serratia marcescens 100000.0 2 PMID:8913500 -4.1.1.86 * vibrio alginolyticus 450000.0 2 PMID:2614383 -4.1.1.87 * acinetobacter calcoaceticus 66000.0 2 PMID:10561613 -4.1.1.87 * klebsiella pneumoniae 142000.0 4 PMID:8620876 -4.1.1.88 * acinetobacter calcoaceticus 185000.0 9 PMID:7961952 -4.1.1.88 * klebsiella pneumoniae 142000.0 4 PMID:8620876 -4.1.1.88 * pseudomonas aeruginosa 140000.0 1 PMID:28757619 -4.1.1.88 * pseudomonas fluorescens 185000.0 5 PMID:7961952 -4.1.1.9 * aix sponsa 190000.0 2 PMID:102255;PMID:827976 -4.1.1.9 * anser sp. 186000.0 2 PMID:102255;PMID:827976 -4.1.1.9 * bos taurus 500000.0 3 PMID:3396325;PMID:4731972 -4.1.1.9 * cairina moschata 47000.0 1 PMID:102255;PMID:827976 -4.1.1.9 * homo sapiens 55000.0 2 PMID:15003260;PMID:24613099 -4.1.1.9 * mycobacterium tuberculosis 44000.0 1 PMID:114118;PMID:6792462 -4.1.1.9 * pseudomonas fluorescens 56000.0 1 PMID:114118 -4.1.1.9 * pseudomonas putida 170000.0 14 PMID:718970;PMID:9851033 -4.1.1.9 * rattus norvegicus 170000.0 8 PMID:101148;PMID:12297032;PMID:16739991;PMID:6792462;PMID:718970;PMID:9843812 -4.1.1.9 * rhizobium leguminosarum 208000.0 3 * -4.1.1.9 * saccharopolyspora erythraea 93000.0 2 PMID:6422856 -4.1.1.90 * bos taurus 99000.0 4 PMID:1749935;PMID:2006163;PMID:2780546;PMID:7819240;PMID:8063763;PMID:8663364;PMID:9115224 -4.1.1.90 * conus textile 130000.0 2 PMID:12473112 -4.1.1.90 * homo sapiens 95000.0 4 PMID:10910912;PMID:1749935;PMID:2006163;PMID:7819240;PMID:9115224 -4.1.1.90 * rattus norvegicus 85700.0 1 PMID:9743593 -4.1.1.91 * cutaneotrichosporon moniliiforme 140000.0 2 PMID:20188702 -4.1.1.92 * glutamicibacter nicotianae 258000.0 1 PMID:12506977 -4.1.1.93 * priestia megaterium 98000.0 2 PMID:9654100 -4.1.1.94 * mus musculus 34000.0 1 PMID:22016388 -4.1.1.95 * niallia circulans 49846.0 2 PMID:15975512 -4.1.1.96 * vibrio alginolyticus 86000.0 4 PMID:7812450 -4.1.1.98 * colwellia psychrerythraea 256300.0 1 PMID:24637760 -4.1.1.98 * escherichia coli 340000.0 4 PMID:15459342;PMID:782527 -4.1.1.98 * pseudomonas aeruginosa 57614.0 1 PMID:23671667 -4.1.1.99 * haloferax volcanii 37328.0 1 PMID:24375100 -4.1.2.10 * chamberlinius hualienensis 47300.0 1 PMID:26261304 -4.1.2.10 * davallia tyermanii 20000.0 1 PMID:29131473 -4.1.2.10 * endophytic bacterium psm-bt4509 14300.0 1 PMID:22226952 -4.1.2.10 * eriobotrya japonica 72000.0 2 PMID:18540101 -4.1.2.10 * nandina domestica 47000.0 4 PMID:29975178 -4.1.2.10 * nedyopus tambanus mangaesinus 52400.0 1 PMID:29445093 -4.1.2.10 * nedyopus tambanus tambanus 52400.0 1 PMID:29445093 -4.1.2.10 * oxidus gracilis 52400.0 1 PMID:29445093 -4.1.2.10 * parafontaria laminata 43000.0 1 PMID:33163773 -4.1.2.10 * parafontaria tonominea 52400.0 1 PMID:29445093 -4.1.2.10 * passiflora edulis 18000.0 6 PMID:25919621;PMID:27914120 -4.1.2.10 * phlebodium aureum 168000.0 2 PMID:12228664 -4.1.2.10 * prunus armeniaca 360000.0 1 * -4.1.2.10 * prunus dulcis 61000.0 1 PMID:11566130 -4.1.2.10 * prunus mume 97000.0 9 PMID:21307605 -4.1.2.10 * prunus pedunculata 61000.0 1 PMID:29890248 -4.1.2.10 * prunus sp. 80000.0 1 PMID:11102786 -4.1.2.10 * prunus turcomanica 100000.0 3 * -4.1.2.11 * sorghum bicolor 180000.0 10 PMID:11102786;PMID:5922969 -4.1.2.11 * ximenia americana 108000.0 4 PMID:2780553 -4.1.2.13 * anoxybacillus gonensis 30900.0 1 PMID:17400540 -4.1.2.13 * avena sativa 44000.0 1 PMID:11197324;PMID:18028878;PMID:18472052 -4.1.2.13 * bacillus cereus 30671.0 2 PMID:21763425 -4.1.2.13 * bacillus methanolicus 129000.0 3 PMID:23760818 -4.1.2.13 * bacillus subtilis 150000.0 3 PMID:28092;PMID:6818420 -4.1.2.13 * bos taurus 162000.0 2 PMID:19072 -4.1.2.13 * callospermophilus lateralis 159000.0 2 PMID:12464282;PMID:2198022;PMID:28092;PMID:2924547;PMID:6818421;PMID:9143366;PMID:9675026 -4.1.2.13 * ceratitis capitata 159000.0 2 PMID:12464282;PMID:2198022;PMID:28092;PMID:6818420 -4.1.2.13 * chara vulgaris 37000.0 2 PMID:16666130 -4.1.2.13 * cyprinus carpio 40000.0 1 PMID:12464282;PMID:2198022;PMID:2924547;PMID:6818421;PMID:9143366;PMID:9675026 -4.1.2.13 * daucus carota 159000.0 2 PMID:12464282;PMID:2198022;PMID:28092;PMID:2924547;PMID:6818421;PMID:9143366;PMID:9675026 -4.1.2.13 * deinococcus radiodurans 70000.0 2 PMID:16502329;PMID:29593097 -4.1.2.13 * edwardsiella ictaluri 77760.0 2 PMID:15531627 -4.1.2.13 * electrophorus electricus 45000.0 1 PMID:17294701 -4.1.2.13 * epiblema scudderiana 160000.0 2 PMID:15896364;PMID:28972169;PMID:33210455 -4.1.2.13 * escherichia coli 340000.0 5 PMID:1155947;PMID:33886681;PMID:348198;PMID:417719 -4.1.2.13 * euglena gracilis 160000.0 4 PMID:12232396 -4.1.2.13 * galdieria sulphuraria 165000.0 2 PMID:10196468 -4.1.2.13 * giardia duodenalis 35380.0 1 PMID:17166851 -4.1.2.13 * gracilariopsis chorda 45000.0 2 * -4.1.2.13 * haloarcula vallismortis 280000.0 2 PMID:1900049 -4.1.2.13 * haloferax mediterranei 110000.0 2 PMID:12501417 -4.1.2.13 * haloferax volcanii 80000.0 2 PMID:22493022 -4.1.2.13 * halothece sp. pcc 7418 239000.0 1 PMID:31356779 -4.1.2.13 * helicobacter pylori 70000.0 1 PMID:16502329;PMID:29593097 -4.1.2.13 * homo sapiens 170000.0 9 PMID:12417303;PMID:12464284;PMID:14766013;PMID:7154951;PMID:7832803;PMID:889843 -4.1.2.13 * lathyrus oleraceus 140000.0 2 PMID:1155947;PMID:348198 -4.1.2.13 * leishmania donovani 44000.0 1 PMID:11197324;PMID:18028878;PMID:18472052 -4.1.2.13 * lethenteron camtschaticum 160000.0 2 PMID:12464282;PMID:2198022;PMID:2924547;PMID:6818421;PMID:9143366;PMID:9675026 -4.1.2.13 * medicago sativa 80000.0 2 PMID:18817750 -4.1.2.13 * methylococcus capsulatus 240000.0 3 PMID:20673213 -4.1.2.13 * metroxylon sagu 160000.0 2 PMID:15896364;PMID:28972169;PMID:33210455 -4.1.2.13 * moritella marina 53000.0 1 PMID:39385 -4.1.2.13 * mycobacterium tuberculosis 158000.0 4 PMID:11237691;PMID:15294302;PMID:21763425;PMID:6818421 -4.1.2.13 * mycolicibacterium smegmatis 158000.0 2 PMID:11237691;PMID:12464282;PMID:15294302;PMID:2198022;PMID:2924547;PMID:6818421;PMID:9143366;PMID:9675026 -4.1.2.13 * neisseria meningitidis 38000.0 1 PMID:20199602 -4.1.2.13 * nephropidae 160000.0 1 PMID:1134354 -4.1.2.13 * nocardia asteroides 165000.0 2 PMID:10196468;PMID:12464282;PMID:2198022;PMID:2924547;PMID:6818421;PMID:9143366;PMID:9675026 -4.1.2.13 * onchocerca volvulus 41000.0 1 PMID:11796620 -4.1.2.13 * opisthorchis viverrini 41710.0 1 PMID:27265876 -4.1.2.13 * oryctolagus cuniculus 160000.0 4 PMID:15896364;PMID:18028878;PMID:28972169;PMID:33210455;PMID:4880215;PMID:743202 -4.1.2.13 * pagrus major 40000.0 1 PMID:12464282;PMID:2198022;PMID:2924547;PMID:6818421;PMID:9143366;PMID:9675026 -4.1.2.13 * peptoniphilus asaccharolyticus 33000.0 1 PMID:237182 -4.1.2.13 * phaseolus vulgaris 40000.0 1 PMID:6420397 -4.1.2.13 * pseudomonas aeruginosa 38441.0 1 PMID:21763425 -4.1.2.13 * pyricularia grisea 79300.0 5 PMID:16901716;PMID:21763425 -4.1.2.13 * pyrobaculum calidifontis 44513.0 1 PMID:28299451 -4.1.2.13 * pyrococcus furiosus 272000.0 2 PMID:11387336 -4.1.2.13 * rattus norvegicus 38000.0 2 PMID:26417114 -4.1.2.13 * ricinus communis 175000.0 2 PMID:12464282;PMID:2198022;PMID:2924547;PMID:6818421;PMID:9143366;PMID:9675026 -4.1.2.13 * schistosoma japonicum 39600.0 2 PMID:18371996;PMID:19079948 -4.1.2.13 * schistosoma mansoni 44000.0 1 PMID:11197324;PMID:18028878;PMID:18472052 -4.1.2.13 * scomber japonicus 40000.0 1 PMID:12464282;PMID:2198022;PMID:2924547;PMID:6818421;PMID:9143366;PMID:9675026 -4.1.2.13 * spinacia oleracea 148000.0 8 PMID:6420397;PMID:6617652 -4.1.2.13 * staphylococcus aureus 34000.0 2 PMID:7408851 -4.1.2.13 * staphylococcus carnosus 70000.0 2 * -4.1.2.13 * synechococcus elongatus pcc 7942 = fachb-805 137000.0 1 * -4.1.2.13 * thermoproteus tenax 241000.0 2 PMID:11387336 -4.1.2.13 * thermus aquaticus 165000.0 6 PMID:11237691;PMID:15294302;PMID:6818421;PMID:8898912 -4.1.2.13 * toxoplasma gondii 160000.0 2 PMID:15896364;PMID:25284756;PMID:28972169;PMID:33210455 -4.1.2.13 * trachemys scripta elegans 37000.0 1 PMID:23874782 -4.1.2.13 * triticum aestivum 142000.0 1 * -4.1.2.13 * vigna radiata 160000.0 2 PMID:15896364;PMID:28972169;PMID:33210455 -4.1.2.13 * zea mays 150000.0 2 PMID:2751305 -4.1.2.14 * azotobacter vinelandii 70000.0 2 PMID:5555562;PMID:8166720 -4.1.2.14 * haloferax volcanii 267000.0 1 PMID:27297879 -4.1.2.14 * pseudomonas fluorescens 87830.0 3 PMID:14245411 -4.1.2.14 * pseudomonas putida 78000.0 6 PMID:5555561;PMID:5555562;PMID:6988426;PMID:8166720 -4.1.2.14 * streptococcus suis 60000.0 3 PMID:18997324 -4.1.2.14 * thermoproteus tenax 33000.0 1 PMID:18186475 -4.1.2.14 * zymomonas mobilis 70000.0 3 PMID:1809834;PMID:6326622 -4.1.2.17 * escherichia coli 24000.0 3 PMID:15299567;PMID:8515438 -4.1.2.17 * glaciozyma antarctica 120000.0 1 PMID:27827354 -4.1.2.19 * escherichia coli 140000.0 5 PMID:14243785;PMID:18308411;PMID:4208690 -4.1.2.19 * thermotoga maritima 114000.0 1 PMID:25324130 -4.1.2.20 * picrophilus oshimae 120000.0 2 PMID:20023024 -4.1.2.21 * mycobacterium sp. 105000.0 1 PMID:6194665 -4.1.2.22 * bifidobacterium animalis subsp. lactis 550000.0 2 PMID:11292814;PMID:20693675 -4.1.2.22 * bifidobacterium breve 600000.0 5 PMID:11292814;PMID:20693675 -4.1.2.22 * bifidobacterium dentium 160000.0 1 PMID:1085128 -4.1.2.22 * bifidobacterium longum 300000.0 4 PMID:11298932;PMID:20674574 -4.1.2.22 * bifidobacterium pseudolongum subsp. globosum 290000.0 1 PMID:1085128 -4.1.2.22 * bifidobacterium sp. 90000.0 1 PMID:15158259 -4.1.2.22 * cupriavidus necator 90000.0 1 PMID:21519932 -4.1.2.22 * lactiplantibacillus paraplantarum 88700.0 1 PMID:18051305 -4.1.2.25 * arabidopsis thaliana 16300.0 5 PMID:15107504 -4.1.2.25 * escherichia coli 104000.0 3 PMID:6990196;PMID:9651328 -4.1.2.25 * haemophilus influenzae 104000.0 2 PMID:9651328 -4.1.2.25 * mycobacterium tuberculosis 62300.0 2 PMID:23150985 -4.1.2.25 * pneumocystis carinii 119000.0 4 PMID:8397083;PMID:9709001 -4.1.2.25 * solanum lycopersicum 14600.0 2 PMID:15107504 -4.1.2.25 * staphylococcus aureus 110000.0 2 PMID:9586996 -4.1.2.25 * streptococcus pneumoniae 100000.0 3 PMID:8385663 -4.1.2.26 * pseudomonas putida 210000.0 5 PMID:16085854;PMID:31152342 -4.1.2.27 * arabidopsis thaliana 59480.0 1 * -4.1.2.27 * homo sapiens 65000.0 6 PMID:10563331;PMID:11018465;PMID:14570870;PMID:17416206;PMID:21184844 -4.1.2.27 * mus musculus 65000.0 2 PMID:10563331;PMID:9464245 -4.1.2.27 * oryza sativa 59480.0 1 * -4.1.2.27 * saccharomyces cerevisiae 65520.0 1 PMID:9334171 -4.1.2.27 * symbiobacterium thermophilum 55000.0 1 PMID:21829623 -4.1.2.27 * trypanosoma brucei brucei 65000.0 1 PMID:32427974 -4.1.2.32 * bacillus sp. (in: firmicutes) 50000.0 2 PMID:5116524 -4.1.2.32 * dosidicus gigas 17700.0 2 PMID:16448210 -4.1.2.32 * illex argentinus 25000.0 1 PMID:34815113 -4.1.2.32 * saurida tumbil 20000.0 1 * -4.1.2.34 * nocardioides sp. 113000.0 3 PMID:9473051 -4.1.2.34 * uncultured bacterium 71000.0 1 PMID:6833175 -4.1.2.35 * saccharomyces cerevisiae 100000.0 2 * -4.1.2.38 * pseudomonas fluorescens 216000.0 11 PMID:17078994;PMID:18314961;PMID:18404768;PMID:19209447;PMID:2496105;PMID:8026749 -4.1.2.4 * aeropyrum pernix 93000.0 2 PMID:12529358 -4.1.2.4 * bacillus cereus 53700.0 2 PMID:1730028 -4.1.2.4 * candidatus aciduliprofundum boonei 53000.0 2 PMID:15205420 -4.1.2.4 * escherichia coli 50000.0 6 PMID:6749498 -4.1.2.4 * haemophilus influenzae 24000.0 1 * -4.1.2.4 * halalkalibacterium halodurans 51700.0 1 PMID:31806708 -4.1.2.4 * haloarcula japonica 55500.0 2 PMID:27215670 -4.1.2.4 * homo sapiens 70000.0 1 PMID:4989681 -4.1.2.4 * hyperthermus butylicus 52000.0 3 * -4.1.2.4 * paenibacillus sp. 24500.0 2 PMID:20622498 -4.1.2.4 * rattus norvegicus 700000.0 3 PMID:6016328 -4.1.2.4 * rhodococcus erythropolis 44000.0 2 PMID:22222309 -4.1.2.4 * salmonella enterica subsp. enterica serovar typhimurium 57300.0 3 PMID:237187;PMID:4618079;PMID:4879701 -4.1.2.4 * streptococcus mutans 23300.0 1 PMID:15057471 -4.1.2.4 * thermococcus kodakarensis 53000.0 2 PMID:15205420 -4.1.2.4 * toxoplasma gondii 57000.0 3 PMID:18950626 -4.1.2.4 * yersinia sp. ea015 24800.0 1 PMID:19505577 -4.1.2.40 * klebsiella pneumoniae 157000.0 1 PMID:6759854 -4.1.2.40 * lactococcus lactis 36476.0 1 PMID:1901863 -4.1.2.40 * staphylococcus aureus 37000.0 1 PMID:7154949 -4.1.2.40 * streptococcus pyogenes 71000.0 5 PMID:20427286;PMID:23316044 -4.1.2.42 * achromobacter xylosoxidans 42000.0 1 * -4.1.2.42 * arthrobacter sp. 51000.0 4 PMID:9346293;PMID:9642221 -4.1.2.42 * delftia sp. 47000.0 1 * -4.1.2.43 * acidomonas methanolica 80000.0 2 PMID:2280713 -4.1.2.43 * bacillus sp. (in: firmicutes) 32000.0 4 PMID:16428816;PMID:2280711 -4.1.2.43 * methanosarcina barkeri 42000.0 1 PMID:16075199 -4.1.2.43 * methylococcus capsulatus 310000.0 4 PMID:16428816;PMID:4219834 -4.1.2.43 * methylomonas aminofaciens 47000.0 5 PMID:16428816;PMID:564713 -4.1.2.43 * methylomonas sp. 44000.0 6 PMID:16428816;PMID:17520247;PMID:28320301 -4.1.2.43 * methylophilus methylotrophus 40000.0 2 PMID:16428816 -4.1.2.43 * methylotuvimicrobium alcaliphilum 40000.0 1 PMID:28320301 -4.1.2.43 * mycobacterium gastri 48000.0 8 PMID:16428816;PMID:17520247;PMID:2280712 -4.1.2.43 * pyrococcus horikoshii 162000.0 4 PMID:15901685 -4.1.2.43 * thermococcus kodakarensis 44000.0 1 PMID:16788179 -4.1.2.44 * aromatoleum evansii 120000.0 3 PMID:12399500;PMID:15916608 -4.1.2.45 * pseudomonas fluorescens 38000.0 1 PMID:21443971 -4.1.2.45 * pseudomonas putida 36640.0 1 PMID:8002605 -4.1.2.45 * rhodococcus opacus 64500.0 1 PMID:31161894 -4.1.2.45 * sphingobium xenophagum 120000.0 2 PMID:8486638 -4.1.2.45 * sphingomonas paucimobilis 116000.0 4 PMID:10731665 -4.1.2.46 * linum usitatissimum 87000.0 7 PMID:3377504;PMID:8387315;PMID:9030531 -4.1.2.47 * baliospermum montanum 65000.0 3 PMID:21352863 -4.1.2.47 * hevea brasiliensis 105000.0 6 PMID:11341923;PMID:19433222 -4.1.2.47 * linum usitatissimum 82000.0 2 PMID:11102786 -4.1.2.47 * manihot esculenta 124000.0 12 PMID:11102786;PMID:12889812;PMID:19433222;PMID:20552449;PMID:8203915;PMID:8900417;PMID:9536038 -4.1.2.48 * aeromonas veronii 40497.0 3 PMID:34424686 -4.1.2.48 * candida albicans 41810.0 1 PMID:10641038 -4.1.2.48 * escherichia coli 140000.0 3 PMID:34424686;PMID:9692922 -4.1.2.48 * pseudomonas putida 40497.0 1 PMID:34424686 -4.1.2.48 * pseudomonas sp. 145000.0 2 PMID:9464392 -4.1.2.48 * saccharomyces cerevisiae 170000.0 3 PMID:9151955 -4.1.2.48 * streptomyces coelicolor 150000.0 3 PMID:18051291 -4.1.2.48 * vanrija humicola 277000.0 1 PMID:5017702;PMID:5438301 -4.1.2.49 * aeromonas jandaei 160000.0 3 PMID:9171400;PMID:9228760 -4.1.2.5 * thermotoga maritima 37000.0 1 PMID:25701680 -4.1.2.51 * picrophilus oshimae 120000.0 2 PMID:20023024 -4.1.2.52 * escherichia coli 28000.0 2 PMID:15996099;PMID:17881002 -4.1.2.54 * trichoderma reesei 37000.0 2 PMID:17609199 -4.1.2.55 * haloferax volcanii 220000.0 1 PMID:32055827 -4.1.2.55 * saccharolobus solfataricus 133000.0 3 PMID:10527934;PMID:11053844 -4.1.2.56 * streptomyces griseus 33000.0 2 PMID:17003031 -4.1.2.61 * pseudomonas fluorescens 186000.0 6 PMID:10222033;PMID:12012244;PMID:15583385;PMID:9461612 -4.1.2.61 * streptomyces sp. 32000.0 1 PMID:23840666 -4.1.2.61 * uncultured organism 198000.0 1 PMID:31841665 -4.1.2.65 * vanilla planifolia 100000.0 3 PMID:29186560 -4.1.2.9 * bifidobacterium animalis subsp. lactis 550000.0 2 PMID:11292814 -4.1.2.9 * debaryomyces hansenii 50000.0 1 * -4.1.2.9 * lactiplantibacillus pentosus 90000.0 2 PMID:11823225;PMID:18430452 -4.1.2.9 * lactiplantibacillus plantarum 90000.0 2 PMID:11823225;PMID:13539033;PMID:18430452 -4.1.2.9 * lactococcus lactis 95727.0 1 PMID:20606278 -4.1.2.9 * metarhizium anisopliae 92450.0 1 PMID:19538505 -4.1.3.1 * acinetobacter calcoaceticus 250000.0 2 PMID:103713;PMID:12382116;PMID:1637186;PMID:1938889;PMID:9395332 -4.1.3.1 * aspergillus fumigatus 61000.0 2 PMID:16603391 -4.1.3.1 * aspergillus nidulans 240000.0 2 PMID:11440123;PMID:17965824 -4.1.3.1 * bacillus sp. (in: firmicutes) 180000.0 2 PMID:236948;PMID:687365 -4.1.3.1 * candida brassicae 290000.0 1 * -4.1.3.1 * candida tropicalis 130000.0 3 PMID:2361956 -4.1.3.1 * chlamydomonas reinhardtii 47510.0 4 PMID:19847013 -4.1.3.1 * citrullus lanatus 277000.0 2 PMID:103713;PMID:12382116;PMID:1637186;PMID:1938889 -4.1.3.1 * colwellia maris 240000.0 4 PMID:103713;PMID:11440123;PMID:12382116;PMID:1637186;PMID:17965824;PMID:1938889 -4.1.3.1 * colwellia psychrerythraea 240000.0 3 PMID:11440123;PMID:17965824 -4.1.3.1 * cucumis sativus 255000.0 3 PMID:103713;PMID:12382116;PMID:1637186;PMID:1938889;PMID:7894014 -4.1.3.1 * dianthus caryophyllus 133000.0 2 PMID:16342929;PMID:6805438 -4.1.3.1 * escherichia coli 208000.0 6 PMID:236948;PMID:3281659;PMID:687365 -4.1.3.1 * euglena gracilis 530000.0 4 PMID:15964777;PMID:21332878 -4.1.3.1 * fomitopsis palustris 186000.0 3 PMID:11888209;PMID:16735748 -4.1.3.1 * geobacillus stearothermophilus 180000.0 2 PMID:236948;PMID:687365 -4.1.3.1 * glycine max 272000.0 6 PMID:20198926 -4.1.3.1 * gossypium hirsutum 64740.0 1 PMID:2194576 -4.1.3.1 * haloferax volcanii 140000.0 2 PMID:6805438;PMID:9738442 -4.1.3.1 * helianthus annuus 114000.0 2 * -4.1.3.1 * hyphomicrobium methylovorum 250000.0 2 PMID:1938889;PMID:9395332 -4.1.3.1 * linum usitatissimum 264000.0 1 PMID:20843;PMID:3947071 -4.1.3.1 * lupinus sp. 260000.0 3 PMID:3947071;PMID:509354 -4.1.3.1 * mycobacterium tuberculosis 200000.0 5 PMID:10572116;PMID:18275086;PMID:25576828;PMID:28432345;PMID:28591590 -4.1.3.1 * paecilomyces variotii 240000.0 1 PMID:11440123;PMID:17965824 -4.1.3.1 * papilio machaon 68000.0 2 PMID:15170371 -4.1.3.1 * paracoccidioides brasiliensis 60000.0 1 PMID:21535474 -4.1.3.1 * pinus densiflora 200000.0 2 * -4.1.3.1 * pinus pinea 264000.0 2 PMID:20843;PMID:3947071 -4.1.3.1 * pinus taeda 270000.0 1 * -4.1.3.1 * prescottella equi 46850.0 1 PMID:11882714 -4.1.3.1 * pseudomonas aeruginosa 60000.0 1 PMID:17319879 -4.1.3.1 * pseudomonas fluorescens 133000.0 2 PMID:15094395 -4.1.3.1 * rattus norvegicus 145000.0 1 PMID:9011236 -4.1.3.1 * rhodopseudomonas sp. 250000.0 2 PMID:1938889;PMID:9395332 -4.1.3.1 * ricinus communis 140000.0 2 PMID:16342929;PMID:6805438;PMID:9738442 -4.1.3.1 * saccharolobus solfataricus 190000.0 1 PMID:20736170 -4.1.3.1 * streptomyces clavuligerus 475000.0 1 PMID:11750062 -4.1.3.1 * sulfolobus acidocaldarius 215000.0 3 PMID:11904155 -4.1.3.1 * turbatrix aceti 480000.0 2 PMID:4209165 -4.1.3.1 * vogesella indigofera 222000.0 1 PMID:14285253 -4.1.3.1 * yarrowia lipolytica 210000.0 2 * -4.1.3.1 * zea mays 252000.0 5 PMID:103713;PMID:12382116;PMID:1637186;PMID:1938889;PMID:19538126 -4.1.3.16 * bos taurus 144500.0 8 PMID:1134356;PMID:1587831;PMID:25372828 -4.1.3.16 * homo sapiens 131500.0 7 PMID:21998747;PMID:22771891;PMID:27096395;PMID:31696211 -4.1.3.16 * rattus norvegicus 120000.0 2 PMID:1134356;PMID:3966804 -4.1.3.17 * phytopseudomonas straminea 160000.0 4 PMID:11826967;PMID:2229032 -4.1.3.17 * pseudomonas putida 150000.0 3 PMID:20843800;PMID:5076765;PMID:7154956 -4.1.3.22 * clostridium tetanomorphum 580000.0 1 PMID:1278156 -4.1.3.24 * cereibacter sphaeroides 220000.0 4 PMID:20047909;PMID:24206647 -4.1.3.24 * chloroflexus aurantiacus 228000.0 4 PMID:12374834;PMID:24206647 -4.1.3.24 * methylorubrum extorquens 190000.0 1 PMID:4447618 -4.1.3.24 * methylotuvimicrobium alcaliphilum 30000.0 1 PMID:33296465 -4.1.3.24 * rhodobacter capsulatus 195000.0 2 PMID:15687206 -4.1.3.25 * chloroflexus aurantiacus 228000.0 2 PMID:24206647 -4.1.3.26 * pseudomonas aeruginosa pao1 33000.0 1 PMID:19597963 -4.1.3.27 * acinetobacter calcoaceticus 86000.0 3 PMID:4349869 -4.1.3.27 * ailanthus altissimus 60000.0 2 * -4.1.3.27 * archaeoglobus fulgidus 150000.0 3 PMID:15235940;PMID:5001612 -4.1.3.27 * bacillus subtilis 80000.0 2 PMID:4275326 -4.1.3.27 * camptotheca acuminata 65013.0 2 PMID:15645305 -4.1.3.27 * catharanthus roseus 143000.0 3 PMID:8444181 -4.1.3.27 * chromobacterium violaceum 54020.0 3 PMID:18949702 -4.1.3.27 * claviceps sp. 400000.0 2 PMID:875641 -4.1.3.27 * comamonas testosteroni 71000.0 2 PMID:4275326 -4.1.3.27 * cupriavidus necator 158000.0 2 PMID:4044 -4.1.3.27 * daucus carota 160000.0 1 PMID:24232024 -4.1.3.27 * delftia acidovorans 71000.0 2 PMID:4275326 -4.1.3.27 * euglena gracilis 80000.0 2 PMID:826535 -4.1.3.27 * mycobacterium tuberculosis 62370.0 3 PMID:18952181 -4.1.3.27 * neurospora crassa 94000.0 4 PMID:125757;PMID:6453559 -4.1.3.27 * nicotiana tabacum 200000.0 2 PMID:24232024 -4.1.3.27 * ogataea henricii 160000.0 3 * -4.1.3.27 * pseudomonas aeruginosa 64000.0 2 PMID:4275326 -4.1.3.27 * pseudomonas putida 63400.0 2 PMID:4692828 -4.1.3.27 * ruta graveolens 220000.0 1 * -4.1.3.27 * saccharolobus solfataricus 139300.0 4 PMID:9016772 -4.1.3.27 * serratia marcescens 150000.0 7 PMID:15235940;PMID:2935703;PMID:4275326;PMID:5001612 -4.1.3.27 * streptomyces sp. 117000.0 3 PMID:306386 -4.1.3.27 * streptomyces venezuelae 66000.0 1 PMID:25355158 -4.1.3.27 * thermococcus kodakarensis 60000.0 5 PMID:11237738 -4.1.3.27 * zea mays 150000.0 1 * -4.1.3.3 * bos taurus 55000.0 1 PMID:5459552;PMID:8828820 -4.1.3.3 * clostridium perfringens 250000.0 8 PMID:10763805;PMID:11432751;PMID:182637;PMID:4333937;PMID:4339794;PMID:4462566 -4.1.3.3 * escherichia coli 135000.0 11 PMID:1646603;PMID:17207253;PMID:17349707;PMID:18521592;PMID:19646958;PMID:19888576;PMID:6389524;PMID:8694758 -4.1.3.3 * escherichia coli k-12 33400.0 2 PMID:18521592;PMID:19888576 -4.1.3.3 * homo sapiens 35200.0 1 PMID:19057931 -4.1.3.3 * lactiplantibacillus plantarum 132000.0 2 PMID:21317263 -4.1.3.3 * latilactobacillus sakei 140000.0 1 PMID:24817128 -4.1.3.3 * limosilactobacillus antri 140000.0 1 PMID:24817128 -4.1.3.3 * pasteurella multocida 33700.0 3 PMID:18521592;PMID:19888576;PMID:24152047 -4.1.3.3 * sphingobacterium sp. 35000.0 1 PMID:36036828 -4.1.3.3 * staphylococcus aureus 33992.0 2 PMID:23418011;PMID:27943302 -4.1.3.3 * sus scrofa 108000.0 3 PMID:10737328;PMID:5459552;PMID:8828820 -4.1.3.30 * aspergillus nidulans 244000.0 4 PMID:11422389;PMID:12897003 -4.1.3.30 * salmonella enterica 32000.0 1 PMID:11422389;PMID:12897003 -4.1.3.30 * toxoplasma gondii 40000.0 1 PMID:23279335 -4.1.3.30 * yarrowia lipolytica 120000.0 1 * -4.1.3.32 * aspergillus niger 110000.0 10 PMID:19133276 -4.1.3.32 * eubacterium barkeri 125000.0 2 PMID:16894175;PMID:527937 -4.1.3.34 * enterococcus faecalis 54000.0 3 * -4.1.3.34 * hydrogenobacter thermophilus 87000.0 2 PMID:15101982 -4.1.3.34 * klebsiella pneumoniae 85000.0 4 PMID:2205500 -4.1.3.34 * lacrimispora sphenoides 56000.0 3 * -4.1.3.34 * lactococcus lactis subsp. lactis 54000.0 3 * -4.1.3.34 * leuconostoc mesenteroides 55000.0 4 PMID:9457870 -4.1.3.34 * rubrivivax gelatinosus 44600.0 2 * -4.1.3.36 * enterococcus faecalis 30000.0 1 PMID:31353747 -4.1.3.36 * escherichia coli 30000.0 1 PMID:21830810 -4.1.3.36 * geobacillus kaustophilus 30000.0 1 PMID:17277450 -4.1.3.36 * staphylococcus aureus 185000.0 1 PMID:18007038 -4.1.3.38 * escherichia coli 50000.0 5 PMID:10876155;PMID:1644759;PMID:2071583;PMID:2251281 -4.1.3.39 * mycobacterium tuberculosis 67000.0 2 PMID:23614353 -4.1.3.39 * pseudomonas sp. 148000.0 5 PMID:12764229;PMID:8419288 -4.1.3.4 * anas sp. 49000.0 2 PMID:6159358 -4.1.3.4 * homo sapiens 65000.0 10 PMID:16330550;PMID:17692550;PMID:8027038;PMID:8440722;PMID:8670134;PMID:9869651 -4.1.3.4 * pseudomonas aeruginosa 33000.0 1 PMID:19597963 -4.1.3.4 * pseudomonas sp. 'mevalonii' 64000.0 2 PMID:10989426;PMID:1332752 -4.1.3.4 * raphanus sativus 70000.0 1 * -4.1.3.40 * escherichia coli 18776.0 3 PMID:1644192;PMID:1644758 -4.1.3.41 * paracoccus denitrificans 80000.0 3 PMID:12835921 -4.1.3.42 * azotobacter vinelandii 70000.0 2 PMID:8166720 -4.1.3.42 * bos taurus 120000.0 1 * -4.1.3.42 * escherichia coli 120000.0 14 PMID:1339418;PMID:3136164;PMID:4560498;PMID:7007372 -4.1.3.43 * paraburkholderia xenovorans 140000.0 3 PMID:19476337 -4.1.3.43 * thermus thermophilus 152000.0 7 PMID:22316175 -4.1.3.44 * pyrococcus abyssi 37800.0 2 PMID:23043105 -4.1.3.45 * streptomyces conglobatus 37600.0 1 PMID:32165500 -4.1.3.46 * chloroflexus aurantiacus 68000.0 3 PMID:17259315 -4.1.3.6 * enterococcus faecalis 580000.0 4 PMID:825122 -4.1.3.6 * escherichia coli 54000.0 6 PMID:10924139;PMID:6354265 -4.1.3.6 * faecalispora sporosphaeroides 536600.0 4 PMID:3994485 -4.1.3.6 * klebsiella pneumoniae 575000.0 18 PMID:1060145;PMID:10924139;PMID:1123340;PMID:4414837;PMID:5156373;PMID:7830578 -4.1.3.6 * lacrimispora sphenoides 515000.0 4 PMID:6127210 -4.1.3.6 * lactococcus lactis 585000.0 1 * -4.1.3.6 * lactococcus lactis subsp. lactis 54000.0 3 * -4.1.3.6 * leuconostoc mesenteroides 55000.0 6 PMID:9457870 -4.1.3.6 * rubrivivax gelatinosus 560000.0 6 PMID:4141604 -4.1.99.1 * aeromonas hydrophila 216000.0 2 PMID:4730321 -4.1.99.1 * escherichia aurescens 55000.0 1 PMID:1097068;PMID:1148216 -4.1.99.1 * escherichia coli 223000.0 10 PMID:1097068;PMID:1148216;PMID:16790938;PMID:17704565;PMID:17937401;PMID:19657572;PMID:19797360;PMID:21601540;PMID:23438036;PMID:236639;PMID:4551942 -4.1.99.1 * fusobacterium necrophorum subsp. funduliforme 244000.0 2 PMID:236027 -4.1.99.1 * klebsiella aerogenes 210000.0 2 PMID:1368766;PMID:7510326;PMID:8534987 -4.1.99.1 * morganella morganii 55000.0 1 PMID:1097068;PMID:1148216 -4.1.99.1 * paenibacillus alvei 208000.0 1 PMID:236639 -4.1.99.1 * porphyromonas gingivalis 52500.0 1 PMID:19246767 -4.1.99.1 * prevotella intermedia 107800.0 2 PMID:21658104 -4.1.99.1 * proteus vulgaris 55000.0 1 PMID:1097068;PMID:1148216 -4.1.99.1 * providencia rettgeri 222000.0 3 PMID:1097068;PMID:1148216 -4.1.99.1 * shigella alkalescens 55000.0 1 PMID:1097068;PMID:1148216 -4.1.99.1 * symbiobacterium thermophilum 210000.0 2 PMID:1368766;PMID:8534987 -4.1.99.11 * azoarcus sp. 260000.0 4 PMID:10483734 -4.1.99.11 * thauera aromatica 230000.0 10 PMID:17105211;PMID:19159265;PMID:9632263 -4.1.99.12 * arabidopsis thaliana 47600.0 2 PMID:23203051 -4.1.99.12 * candida albicans 41000.0 3 PMID:15328619 -4.1.99.12 * escherichia coli 47000.0 7 PMID:10103033;PMID:11112287;PMID:11687623 -4.1.99.12 * escherichia coli k-12 23251.0 1 PMID:9211332 -4.1.99.12 * methanocaldococcus jannaschii 51600.0 3 PMID:11687623;PMID:12200440 -4.1.99.12 * meyerozyma guilliermondii 30000.0 2 PMID:2246238 -4.1.99.12 * saccharomyces cerevisiae 28000.0 2 PMID:12595523 -4.1.99.12 * salmonella enterica subsp. enterica serovar typhimurium 50000.0 3 PMID:20806221 -4.1.99.12 * streptococcus pneumoniae 35350.0 1 PMID:23954596 -4.1.99.13 * aphrocallistes vastus 65000.0 2 PMID:14499587 -4.1.99.13 * drosophila melanogaster 110000.0 3 PMID:16793367;PMID:8600518;PMID:9447230 -4.1.99.13 * dunaliella salina 67000.0 1 PMID:16614917 -4.1.99.13 * homo sapiens 63000.0 2 PMID:8604344;PMID:9330615 -4.1.99.14 * bacillus subtilis 40000.0 1 PMID:21671623 -4.1.99.14 * clostridium acetobutylicum 41000.0 1 PMID:20405152 -4.1.99.17 * arabidopsis thaliana 71994.0 1 PMID:18048325 -4.1.99.17 * escherichia coli 68000.0 1 PMID:15326535 -4.1.99.17 * salmonella enterica subsp. enterica serovar typhimurium 70000.0 1 PMID:19113839 -4.1.99.19 * escherichia coli 44143.0 2 PMID:12650933 -4.1.99.2 * aeromonas phenologenes 380000.0 1 PMID:16345185 -4.1.99.2 * citrobacter freundii 220000.0 4 PMID:16793353;PMID:17094783;PMID:24022778 -4.1.99.2 * morganella morganii 215000.0 1 PMID:32236865 -4.1.99.2 * pantoea agglomerans 159000.0 1 * -4.1.99.2 * symbiobacterium sp. 202000.0 3 PMID:9425630 -4.1.99.2 * symbiobacterium thermophilum 200000.0 3 PMID:7763716 -4.1.99.20 * streptomyces griseus 54000.0 2 PMID:17003031 -4.1.99.22 * staphylococcus aureus 82000.0 4 PMID:15317939 -4.1.99.26 * mycobacterium ulcerans 42000.0 1 PMID:30628436 -4.1.99.28 * microbacterium sp. 5-2b 49000.0 1 PMID:34728636 -4.1.99.3 * acinetobacter sp. 60000.0 1 PMID:24637630 -4.1.99.3 * arabidopsis thaliana 64983.0 3 PMID:10447684;PMID:11971912;PMID:19074258 -4.1.99.3 * bombyx mori 42000.0 1 * -4.1.99.3 * chlamydomonas reinhardtii 100000.0 1 PMID:10527430 -4.1.99.3 * chrysodeixis chalcites nucleopolyhedrovirus 83000.0 4 PMID:18547877;PMID:19955559 -4.1.99.3 * escherichia coli 54000.0 8 PMID:1103968;PMID:17951115;PMID:18471009;PMID:2204823;PMID:331349;PMID:6325459;PMID:6774746 -4.1.99.3 * fowlpox virus 54500.0 1 PMID:11160666 -4.1.99.3 * glycine max 85000.0 1 PMID:18270478 -4.1.99.3 * halobacterium salinarum 53065.0 1 PMID:2204823 -4.1.99.3 * homo sapiens 40000.0 1 PMID:4818913 -4.1.99.3 * hordeum vulgare 54000.0 1 PMID:23220084 -4.1.99.3 * neurospora crassa 66000.0 1 PMID:7938208 -4.1.99.3 * oryza meridionalis 56000.0 2 PMID:23220084 -4.1.99.3 * oryza sativa 56000.0 2 PMID:21251107 -4.1.99.3 * oryza sativa japonica group 56000.0 5 PMID:18235036;PMID:23220084 -4.1.99.3 * saccharomyces cerevisiae 85000.0 11 PMID:1103968;PMID:2204823;PMID:331350;PMID:339241;PMID:6989394 -4.1.99.3 * salmonella enterica subsp. enterica serovar typhimurium 54000.0 2 PMID:1840665 -4.1.99.3 * scenedesmus acutus 56000.0 1 PMID:2204823 -4.1.99.3 * streptomyces griseus 50594.0 3 PMID:2204823 -4.1.99.3 * synechococcus elongatus pcc 7942 = fachb-805 93000.0 4 PMID:17573708;PMID:2204823;PMID:2837735 -4.1.99.3 * triticum aestivum 56000.0 2 PMID:23220084 -4.1.99.3 * xenopus laevis 65000.0 1 PMID:16302973 -4.1.99.3 * zea mays 54000.0 1 PMID:23220084 -4.1.99.5 * botryococcus braunii 66000.0 2 PMID:10103026;PMID:1608940 -4.1.99.5 * lathyrus oleraceus 67000.0 1 PMID:10845712 -4.1.99.5 * synechococcus elongatus 26400.0 1 PMID:23759169 -4.2.1.1 * acipenser gueldenstaedtii 29000.0 1 PMID:17208453;PMID:21381885 -4.2.1.1 * alces alces 27500.0 1 PMID:4205073 -4.2.1.1 * anguilla anguilla 31200.0 1 PMID:11807116 -4.2.1.1 * aspergillus fumigatus 92000.0 1 PMID:32975213 -4.2.1.1 * astrosclera willeyana 33200.0 1 PMID:22285172 -4.2.1.1 * azospirillum brasilense 120000.0 2 PMID:19694814 -4.2.1.1 * bacillus subtilis 37000.0 1 * -4.2.1.1 * bos taurus 53000.0 5 PMID:11960690;PMID:12499545;PMID:15039588;PMID:15671337;PMID:3921058;PMID:3929690;PMID:6811592 -4.2.1.1 * brucella suis 25000.0 2 PMID:20158185;PMID:21251841 -4.2.1.1 * canis lupus familiaris 28500.0 1 PMID:4209623;PMID:6767497 -4.2.1.1 * carcinus maenas 32119.0 1 PMID:8037456 -4.2.1.1 * cavia porcellus 30000.0 2 PMID:15671337;PMID:3921058;PMID:3929690;PMID:403527;PMID:4627453;PMID:9857211 -4.2.1.1 * chionodraco hamatus 287600.0 3 PMID:11807116;PMID:17510781 -4.2.1.1 * chlamydomonas reinhardtii 165000.0 8 PMID:1368343;PMID:18405332;PMID:8876257 -4.2.1.1 * chlorella sorokiniana 100000.0 2 PMID:9821693 -4.2.1.1 * clostridium perfringens 88000.0 2 PMID:23475974 -4.2.1.1 * coccomyxa sp. 80500.0 1 PMID:7766041 -4.2.1.1 * columba livia 30000.0 1 PMID:21476925 -4.2.1.1 * colwellia psychrerythraea 55000.0 1 PMID:26778292 -4.2.1.1 * conticribra weissflogii 34000.0 2 PMID:11015190;PMID:23769640;PMID:24268544 -4.2.1.1 * danio rerio 280000.0 1 PMID:29230365 -4.2.1.1 * dicentrarchus labrax 30200.0 1 PMID:21787732 -4.2.1.1 * dunaliella 59000.0 1 PMID:22715026 -4.2.1.1 * dunaliella salina 60000.0 2 PMID:10556554;PMID:12651119;PMID:12777782 -4.2.1.1 * elephas trogontherii 39000.0 4 PMID:17970284 -4.2.1.1 * equus caballus 27000.0 1 PMID:6800366 -4.2.1.1 * escherichia coli 25100.0 2 PMID:18342550;PMID:18405334;PMID:19218391;PMID:19224556 -4.2.1.1 * gallus gallus 30000.0 3 PMID:410641;PMID:4621976 -4.2.1.1 * haemophilus influenzae 100000.0 1 PMID:21531201 -4.2.1.1 * halalkalibacterium halodurans 79500.0 2 PMID:27102616;PMID:27174908 -4.2.1.1 * helicobacter pylori 29000.0 2 PMID:11341916;PMID:22974493 -4.2.1.1 * homo sapiens 214000.0 18 PMID:11015219;PMID:11121027;PMID:11493685;PMID:11553764;PMID:11802772;PMID:12009884;PMID:12499545;PMID:14600151;PMID:15039588;PMID:19367501;PMID:2111324;PMID:2433278;PMID:29564477;PMID:35947329 -4.2.1.1 * hydrogenovibrio crunogenus 66000.0 1 PMID:26249355 -4.2.1.1 * lactuca sativa 195000.0 2 PMID:812792 -4.2.1.1 * lathyrus oleraceus 194000.0 6 PMID:10747009;PMID:18342550;PMID:18405334;PMID:19218391;PMID:19224556;PMID:4210017;PMID:9882424 -4.2.1.1 * leishmania chagasi 35000.0 1 PMID:23977960 -4.2.1.1 * leptonychotes weddellii 30000.0 1 PMID:21377369 -4.2.1.1 * macropus eugenii desmarest 30700.0 2 PMID:6817802 -4.2.1.1 * malassezia globosa 34000.0 1 PMID:23391336 -4.2.1.1 * mesorhizobium loti 27200.0 2 PMID:18342550;PMID:18405334;PMID:19218391;PMID:19224556 -4.2.1.1 * methanosarcina thermophila 84000.0 14 PMID:10529183;PMID:10924116;PMID:11781108;PMID:20023030;PMID:8041719;PMID:8655508 -4.2.1.1 * methanothermobacter thermautotrophicus 90000.0 3 PMID:10515911 -4.2.1.1 * mus musculus 120000.0 5 PMID:10556554;PMID:12777782;PMID:14600151;PMID:14660577 -4.2.1.1 * mytilus galloprovincialis 50000.0 2 PMID:20462499;PMID:28229634 -4.2.1.1 * myxine glutinosa 28500.0 1 PMID:4209623;PMID:6767497 -4.2.1.1 * neisseria gonorrhoeae 28085.0 3 PMID:18342550;PMID:18405334;PMID:19218391;PMID:19224556;PMID:9108244 -4.2.1.1 * neisseria sicca 30000.0 2 PMID:403527;PMID:4627453;PMID:9857211 -4.2.1.1 * nicotiana tabacum 220000.0 2 PMID:12185253 -4.2.1.1 * oncorhynchus mykiss 31000.0 6 PMID:18288451;PMID:18537745 -4.2.1.1 * oryza sativa 29000.0 1 PMID:17208453;PMID:21381885 -4.2.1.1 * ovis aries 540000.0 7 PMID:11341916;PMID:114424;PMID:22974493;PMID:3124821;PMID:410641 -4.2.1.1 * phaeodactylum tricornutum 380000.0 2 PMID:32627740 -4.2.1.1 * platichthys flesus 30000.0 1 PMID:403527;PMID:4627453;PMID:9857211 -4.2.1.1 * populus tremula 205000.0 2 PMID:9247540 -4.2.1.1 * porphyromonas gingivalis 32300.0 1 PMID:23769640;PMID:24268544 -4.2.1.1 * pseudomonas fragi 94000.0 2 * -4.2.1.1 * rattus norvegicus 46000.0 4 PMID:11553764;PMID:403951;PMID:6425289 -4.2.1.1 * rhodospirillum rubrum 30000.0 3 PMID:403527;PMID:4627453;PMID:9857211 -4.2.1.1 * solanum tuberosum 255000.0 5 PMID:8680307 -4.2.1.1 * sordaria macrospora 25900.0 2 PMID:24506675 -4.2.1.1 * spinacia oleracea 212000.0 3 PMID:413832;PMID:4210017 -4.2.1.1 * stylophora pistillata 36600.0 1 PMID:18617510 -4.2.1.1 * sulfurihydrogenibium yellowstonense 26000.0 1 PMID:22803664;PMID:23181552 -4.2.1.1 * sus scrofa 30000.0 1 PMID:15671337;PMID:3921058;PMID:3929690 -4.2.1.1 * thalassiosira pseudonana 25000.0 1 PMID:18342550;PMID:18405334;PMID:19218391;PMID:19224556 -4.2.1.1 * trematomus bernacchii 29900.0 1 PMID:11807116 -4.2.1.1 * trichomonas vaginalis 44300.0 2 PMID:32515610;PMID:34652457 -4.2.1.1 * trypanosoma cruzi 34000.0 1 PMID:23391336 -4.2.1.1 * vibrio cholerae serotype o1 26000.0 1 PMID:22803664;PMID:23181552 -4.2.1.10 * amycolatopsis methanolica 135000.0 2 PMID:1479361 -4.2.1.10 * aquifex aeolicus 27000.0 1 PMID:23396056 -4.2.1.10 * archaeoglobus fulgidus 52000.0 2 PMID:18931429 -4.2.1.10 * aspergillus nidulans 200000.0 3 PMID:1554351;PMID:2949740 -4.2.1.10 * escherichia coli 58000.0 4 PMID:1554351;PMID:2950851;PMID:3037262 -4.2.1.10 * gluconobacter oxydans 191000.0 7 PMID:18540103;PMID:24352733 -4.2.1.10 * helicobacter pylori 230000.0 2 PMID:8912695 -4.2.1.10 * neurospora crassa 232000.0 4 PMID:125280;PMID:4263953;PMID:6214255 -4.2.1.10 * physcomitrium patens 49500.0 1 PMID:687649 -4.2.1.10 * salmonella enterica subsp. enterica serovar typhi 61500.0 2 PMID:8216229 -4.2.1.10 * streptomyces coelicolor 209000.0 2 PMID:2306211 -4.2.1.100 * geobacter metallireducens 92000.0 6 PMID:17122342 -4.2.1.100 * syntrophus aciditrophicus 115000.0 3 PMID:17122342 -4.2.1.100 * thauera aromatica 55000.0 2 PMID:9738901 -4.2.1.103 * arthrobacter pascens 530000.0 2 PMID:20826798 -4.2.1.103 * pseudomonas fluorescens 43700.0 3 PMID:20630867 -4.2.1.103 * pseudomonas putida 59000.0 2 PMID:11306561;PMID:12244065 -4.2.1.104 * arabidopsis thaliana 21900.0 1 PMID:21494323 -4.2.1.104 * ectopseudomonas oleovorans 17008.0 2 PMID:18708510;PMID:20004515 -4.2.1.104 * escherichia coli 170000.0 8 PMID:10801492;PMID:3128546;PMID:3323528;PMID:6336748;PMID:6994799 -4.2.1.104 * oryza sativa 22000.0 2 PMID:19691286;PMID:21494323 -4.2.1.104 * pseudomonas putida 17008.0 1 PMID:20004515 -4.2.1.104 * serratia proteamaculans 220000.0 2 PMID:25849512 -4.2.1.104 * sordaria macrospora 19000.0 1 PMID:18796334 -4.2.1.104 * synechococcus sp. 50000.0 2 PMID:21057026;PMID:9294430 -4.2.1.104 * tetranychus urticae 670000.0 2 PMID:28613863 -4.2.1.104 * thiohalophilus thiocyanatoxydans 70000.0 2 PMID:17964868 -4.2.1.105 * pueraria montana var. lobata 38000.0 2 * -4.2.1.106 * eubacterium sp. 114000.0 4 PMID:3558364;PMID:8808760 -4.2.1.107 * rattus norvegicus 46580.0 2 * -4.2.1.108 * halalkalibacterium halodurans 15000.0 1 PMID:18488150;PMID:18629475 -4.2.1.108 * halomonas elongata 35000.0 3 PMID:21468713;PMID:9864317 -4.2.1.108 * paenibacillus lautus 32200.0 1 PMID:30674920 -4.2.1.108 * sphingopyxis alaskensis 32700.0 1 PMID:26249694 -4.2.1.109 * bacillus subtilis 90000.0 2 PMID:18391471 -4.2.1.11 * aphidius ervi 98000.0 2 PMID:19786101 -4.2.1.11 * arabidopsis thaliana 61200.0 2 PMID:19223001 -4.2.1.11 * bacillus anthracis 47000.0 1 PMID:18456007;PMID:19957447;PMID:20174608 -4.2.1.11 * bacteroides fragilis 49000.0 1 PMID:15716066 -4.2.1.11 * besnoitia darlingi 47000.0 1 PMID:18625501 -4.2.1.11 * bifidobacterium animalis subsp. lactis 50000.0 1 PMID:15606772;PMID:17382932;PMID:19574304 -4.2.1.11 * borreliella burgdorferi 50000.0 2 PMID:22083700;PMID:22087329 -4.2.1.11 * botrytis cinerea 48000.0 1 PMID:16779678;PMID:19011901;PMID:19220903;PMID:20045689 -4.2.1.11 * brucella abortus 49000.0 1 PMID:21674187 -4.2.1.11 * candida albicans 47000.0 2 PMID:10825670;PMID:15063749;PMID:20433201;PMID:21621582;PMID:22750626 -4.2.1.11 * candida parapsilosis 47000.0 1 PMID:15063749;PMID:20433201;PMID:21621582;PMID:22750626 -4.2.1.11 * citrus trifoliata 47790.0 1 * -4.2.1.11 * clavispora lusitaniae 47000.0 1 PMID:15063749;PMID:20433201;PMID:21621582;PMID:22750626 -4.2.1.11 * clostridioides difficile 338000.0 4 PMID:22087329;PMID:2365093 -4.2.1.11 * curvularia lunata 48000.0 1 PMID:16779678;PMID:19011901;PMID:19220903;PMID:20045689 -4.2.1.11 * cyprinus carpio 94000.0 2 * -4.2.1.11 * echinostoma caproni 46000.0 1 PMID:17462631 -4.2.1.11 * eimeria tenella 50000.0 1 PMID:17030033 -4.2.1.11 * entamoeba histolytica 48000.0 2 PMID:18456007;PMID:19957447;PMID:20174608;PMID:21619880;PMID:22569588 -4.2.1.11 * entamoeba invadens 48000.0 1 PMID:16779678;PMID:19011901;PMID:19220903;PMID:20045689 -4.2.1.11 * enterococcus hirae 46620.0 2 PMID:12869539 -4.2.1.11 * escherichia coli 92000.0 4 PMID:11676541;PMID:4942326 -4.2.1.11 * fasciola hepatica 47000.0 1 PMID:15063749;PMID:20433201;PMID:21621582;PMID:22750626 -4.2.1.11 * gallus gallus 100000.0 6 PMID:15606772;PMID:4093440 -4.2.1.11 * giardia duodenalis 48000.0 1 PMID:21619880;PMID:22569588 -4.2.1.11 * haemonchus contortus 49000.0 2 PMID:21444098 -4.2.1.11 * hevea brasiliensis 47600.0 1 PMID:11106410 -4.2.1.11 * homo sapiens 100000.0 14 PMID:10071935;PMID:1134359;PMID:15063749;PMID:16663518;PMID:18456007;PMID:19255486;PMID:19780894;PMID:19957447;PMID:20174608;PMID:20433201;PMID:21621582;PMID:22750626;PMID:24664479;PMID:7357031;PMID:9003434;PMID:9178938 -4.2.1.11 * klebsiella pneumoniae 94000.0 3 PMID:15985223;PMID:8784922 -4.2.1.11 * lactiplantibacillus plantarum 48060.0 3 PMID:16779678;PMID:19011901;PMID:19220903;PMID:20045689;PMID:23103380 -4.2.1.11 * leishmania mexicana 50000.0 1 PMID:15606772;PMID:17382932;PMID:19574304 -4.2.1.11 * leuconostoc mesenteroides 51400.0 2 PMID:16734786 -4.2.1.11 * macaca mulatta 82000.0 1 PMID:4622436 -4.2.1.11 * mus musculus 47450.0 1 PMID:21803152 -4.2.1.11 * nakaseomyces glabratus 47000.0 1 PMID:15063749;PMID:20433201;PMID:21621582;PMID:22750626 -4.2.1.11 * oryctolagus cuniculus 92000.0 5 PMID:12044909;PMID:24664479;PMID:8784922 -4.2.1.11 * pagrus major 95500.0 2 PMID:4199858 -4.2.1.11 * paracoccidioides brasiliensis 54000.0 1 PMID:19429745 -4.2.1.11 * pichia kudriavzevii 47000.0 1 PMID:15063749;PMID:20433201;PMID:21621582;PMID:22750626 -4.2.1.11 * plasmodium falciparum 155000.0 7 PMID:15606772;PMID:17382932;PMID:19268421;PMID:19574304;PMID:4093440 -4.2.1.11 * priestia megaterium 335000.0 2 PMID:25885 -4.2.1.11 * pyrococcus furiosus 46000.0 1 PMID:18651835;PMID:8080274 -4.2.1.11 * rattus norvegicus 93000.0 12 PMID:1394640;PMID:15063749;PMID:18468517;PMID:20433201;PMID:21621582;PMID:22750626;PMID:2865729;PMID:4413246;PMID:7400110 -4.2.1.11 * saccharolobus solfataricus 46700.0 1 * -4.2.1.11 * saccharomyces cerevisiae 96000.0 13 PMID:10508418;PMID:13678299;PMID:16738406;PMID:18651835;PMID:23359425;PMID:6353993;PMID:8080274 -4.2.1.11 * sarcocystis dasypi 47000.0 1 PMID:18625501 -4.2.1.11 * sarcocystis falcatula 47000.0 1 PMID:18625501 -4.2.1.11 * sarcocystis neurona 47000.0 1 PMID:18625501 -4.2.1.11 * schistosoma japonicum 50000.0 1 PMID:20512506 -4.2.1.11 * scomber japonicus 93000.0 2 PMID:16663518;PMID:24664479;PMID:7357031;PMID:9003434 -4.2.1.11 * spinacia oleracea 93000.0 2 PMID:16663518;PMID:24664479;PMID:7357031;PMID:9003434 -4.2.1.11 * staphylococcus aureus 52000.0 1 PMID:15158195 -4.2.1.11 * steinernema glaseri 47200.0 2 PMID:15063749;PMID:20433201;PMID:21621582;PMID:22750626 -4.2.1.11 * streptococcus mutans 350000.0 2 PMID:1521304 -4.2.1.11 * streptococcus pneumoniae 370000.0 2 PMID:12435062;PMID:15476816 -4.2.1.11 * streptococcus pyogenes 452000.0 1 PMID:20098674 -4.2.1.11 * streptococcus ratti 49000.0 2 PMID:2318530 -4.2.1.11 * streptococcus suis 440000.0 3 PMID:18757800;PMID:19848587;PMID:23055041 -4.2.1.11 * sus scrofa 110000.0 11 PMID:10071935;PMID:1134359;PMID:4199858;PMID:8593189 -4.2.1.11 * theileria annulata 93000.0 2 PMID:16663518;PMID:24664479;PMID:9003434 -4.2.1.11 * thermotoga maritima 345000.0 2 PMID:7757011 -4.2.1.11 * toxoplasma gondii 48000.0 1 PMID:19770069 -4.2.1.11 * trichinella spiralis 46000.0 1 PMID:15928906 -4.2.1.11 * trypanosoma brucei 46461.0 1 PMID:12869196 -4.2.1.11 * vibrio parahaemolyticus 52000.0 2 PMID:24430205 -4.2.1.11 * zea mays 56000.0 1 * -4.2.1.110 * phanerodontia chrysosporium 98746.0 3 PMID:15716041;PMID:22330145 -4.2.1.110 * polyporus obtusus 200000.0 2 PMID:1423351 -4.2.1.111 * anthracobia melaloma 230000.0 4 PMID:15110094;PMID:16822618 -4.2.1.112 * syntrophotalea acetylenica 85000.0 5 PMID:10447686;PMID:16511024;PMID:7592321 -4.2.1.113 * escherichia coli 195500.0 4 PMID:10978150;PMID:14661953;PMID:3300553 -4.2.1.115 * helicobacter pylori 75000.0 2 PMID:10954725 -4.2.1.115 * pseudomonas aeruginosa 64000.0 3 PMID:11580835 -4.2.1.116 * metallosphaera sedula 220000.0 4 PMID:19429610;PMID:27771364 -4.2.1.117 * shewanella oneidensis 94000.0 1 PMID:14702315 -4.2.1.118 * gluconobacter oxydans 76000.0 1 PMID:20460715 -4.2.1.118 * neurospora crassa 40367.0 3 PMID:149131;PMID:6241580 -4.2.1.118 * penicillium parvum 39550.0 1 PMID:35612974 -4.2.1.119 * aeromonas caviae 30000.0 2 PMID:9457873 -4.2.1.119 * arabidopsis thaliana 34000.0 1 PMID:16982622 -4.2.1.119 * candida tropicalis 63000.0 1 PMID:12832794 -4.2.1.119 * cucumis sativus 65000.0 2 PMID:1879422 -4.2.1.119 * cupriavidus necator 17500.0 3 PMID:22081565 -4.2.1.119 * drosophila melanogaster 64100.0 1 PMID:21320074 -4.2.1.119 * homo sapiens 45000.0 1 PMID:10671535 -4.2.1.119 * rattus norvegicus 155000.0 8 PMID:20566640;PMID:8408009;PMID:8993540 -4.2.1.12 * escherichia coli 66000.0 1 PMID:8544815 -4.2.1.12 * zymomonas mobilis 130000.0 2 PMID:6326623 -4.2.1.120 * clostridium aminobutyricum 232000.0 2 PMID:8344309 -4.2.1.120 * clostridium kluyveri 237000.0 2 PMID:8161284 -4.2.1.121 * solanum lycopersicum 55254.0 1 PMID:11060314 -4.2.1.122 * thermotoga maritima 98000.0 4 PMID:11756459 -4.2.1.123 * tetrahymena thermophila 72000.0 2 PMID:1892870;PMID:21531832 -4.2.1.125 * panax ginseng 89000.0 4 PMID:16962103;PMID:17088293;PMID:23484102 -4.2.1.125 * panax quinquefolius 88400.0 1 PMID:24929308 -4.2.1.127 * castellaniella defragrans 160000.0 2 PMID:20663876 -4.2.1.127 * thauera linaloolentis 600000.0 1 PMID:26979141 -4.2.1.129 * alicyclobacillus acidocaldarius 71600.0 1 PMID:21531832 -4.2.1.129 * bradyrhizobium japonicum 76300.0 1 PMID:21531832 -4.2.1.129 * methylococcus capsulatus 74100.0 1 PMID:21531832 -4.2.1.129 * rhodopseudomonas palustris 72300.0 1 PMID:21531832 -4.2.1.129 * streptomyces peucetius 74100.0 1 PMID:21531832 -4.2.1.129 * tetrahymena thermophila 71600.0 1 PMID:21531832 -4.2.1.129 * zymomonas mobilis 74100.0 1 PMID:21531832 -4.2.1.130 * arabidopsis thaliana 132000.0 10 PMID:23651081 -4.2.1.130 * escherichia coli 82000.0 4 PMID:7848303 -4.2.1.131 * rhodobacter capsulatus 44000.0 1 PMID:12745254 -4.2.1.131 * rubrivivax gelatinosus 44000.0 2 PMID:12745254;PMID:21590288 -4.2.1.131 * thiocapsa roseopersicina 38000.0 1 PMID:21590288 -4.2.1.134 * homo sapiens 70600.0 4 PMID:18554506 -4.2.1.135 * bacillus cereus 26700.0 1 PMID:26207987 -4.2.1.135 * campylobacter jejuni 93000.0 1 PMID:17087520 -4.2.1.138 * streptomyces griseus 41000.0 1 PMID:21693706 -4.2.1.139 * medicago sativa 70000.0 3 PMID:7805842;PMID:8071365 -4.2.1.140 * picrophilus oshimae 340000.0 2 PMID:20023024 -4.2.1.140 * saccharolobus solfataricus 48000.0 3 PMID:15474024 -4.2.1.141 * saccharolobus solfataricus 132900.0 2 PMID:16849334 -4.2.1.142 * aspergillus parasiticus 158000.0 2 PMID:14602595 -4.2.1.143 * aspergillus parasiticus 140000.0 10 PMID:15258720;PMID:1731640;PMID:8662689;PMID:8784203;PMID:8995367 -4.2.1.144 * amycolatopsis mediterranei 74000.0 3 PMID:9497318 -4.2.1.144 * streptomyces sp. 42700.0 1 * -4.2.1.147 * methylorubrum extorquens 60000.0 2 PMID:11073907 -4.2.1.148 * cereibacter sphaeroides 80000.0 2 PMID:18065535 -4.2.1.148 * chloroflexus aurantiacus 80000.0 2 PMID:18065535 -4.2.1.148 * haloarcula hispanica 86000.0 2 PMID:28932214 -4.2.1.149 * escherichia coli 87000.0 3 PMID:11551212;PMID:7815937 -4.2.1.149 * proteus sp. (in: enterobacteria) 91100.0 5 PMID:11409545;PMID:15731894 -4.2.1.150 * clostridium acetobutylicum 158000.0 6 PMID:5057466;PMID:7024731;PMID:8655474 -4.2.1.150 * meiothermus ruber 140000.0 1 * -4.2.1.150 * metallosphaera sedula 70000.0 1 PMID:21169482 -4.2.1.151 * thermus thermophilus 30500.0 1 PMID:24083939 -4.2.1.153 * cereibacter sphaeroides 37000.0 1 PMID:18065535 -4.2.1.153 * chloroflexus aurantiacus 38000.0 2 PMID:18065535;PMID:19955419 -4.2.1.154 * streptomyces glaucescens 37500.0 3 PMID:8218177 -4.2.1.157 * clostridioides difficile 148000.0 5 PMID:15654892;PMID:20146278 -4.2.1.163 * escherichia coli 32500.0 1 PMID:7737515 -4.2.1.164 * saccharopolyspora spinosa 109400.0 2 PMID:18345667 -4.2.1.165 * chlorobaculum tepidum 25000.0 1 PMID:26088139 -4.2.1.167 * [clostridium] symbiosum 100000.0 8 PMID:10491198;PMID:21434666 -4.2.1.167 * acidaminococcus fermentans 55000.0 4 PMID:3691501 -4.2.1.17 * clostridium acetobutylicum 158000.0 2 PMID:5057466 -4.2.1.17 * cupriavidus necator 87000.0 1 PMID:25401070 -4.2.1.17 * escherichia coli 420000.0 3 PMID:7012144 -4.2.1.17 * homo sapiens 460000.0 3 PMID:20825197 -4.2.1.17 * rattus norvegicus 161000.0 1 PMID:8895557 -4.2.1.17 * sus scrofa 155000.0 2 PMID:833142 -4.2.1.171 * thermococcus kodakarensis 70000.0 1 PMID:34099860 -4.2.1.175 * clostridium sporogenes 46000.0 3 PMID:10849007 -4.2.1.178 * arthrobacter sp. h65-7 125000.0 1 * -4.2.1.178 * paenarthrobacter aurescens 145000.0 1 PMID:26555784 -4.2.1.178 * pseudarthrobacter chlorophenolicus 139000.0 1 * -4.2.1.18 * acinetobacter sp. 109000.0 4 PMID:16482430 -4.2.1.18 * homo sapiens 221400.0 2 PMID:18831052 -4.2.1.180 * thauera aromatica 110000.0 1 PMID:34601806 -4.2.1.19 * arabidopsis thaliana 540000.0 1 PMID:7480319 -4.2.1.19 * cryptococcus neoformans 22000.0 1 PMID:8045413 -4.2.1.19 * mycobacterium tuberculosis 570000.0 1 PMID:24311587 -4.2.1.19 * saccharomyces cerevisiae 500000.0 6 PMID:4611478;PMID:7887893 -4.2.1.19 * salmonella enterica subsp. enterica serovar typhimurium 260000.0 2 PMID:6246956 -4.2.1.19 * trichoderma harzianum 22466.0 1 PMID:1406594 -4.2.1.19 * triticum aestivum 670000.0 4 PMID:12231975;PMID:7480319 -4.2.1.2 * arabidopsis thaliana 216000.0 2 PMID:29688630 -4.2.1.2 * ascaris suum 51000.0 2 PMID:14711508 -4.2.1.2 * bacteria 114000.0 2 PMID:3932328;PMID:8593099 -4.2.1.2 * corynebacterium glutamicum 200000.0 2 PMID:1633200;PMID:16717409;PMID:17960613 -4.2.1.2 * escherichia coli 200000.0 10 PMID:1917897;PMID:23405168;PMID:26070669;PMID:26658641;PMID:3282546;PMID:3291870;PMID:3932328 -4.2.1.2 * escherichia coli k-12 60105.0 2 PMID:26070669;PMID:26658641 -4.2.1.2 * escherichia coli o157:h7 60105.0 2 PMID:26070669;PMID:26658641 -4.2.1.2 * euglena gracilis 120000.0 2 PMID:23405168;PMID:3932328;PMID:8593099 -4.2.1.2 * geobacillus stearothermophilus 180000.0 1 PMID:939272 -4.2.1.2 * helicobacter pylori 600000.0 3 PMID:21818585 -4.2.1.2 * homo sapiens 210000.0 4 PMID:1633200;PMID:16717409;PMID:17960613;PMID:18313410;PMID:29456767 -4.2.1.2 * lathyrus oleraceus 190000.0 2 PMID:9390175 -4.2.1.2 * leishmania major 62600.0 2 PMID:22569531 -4.2.1.2 * paraburkholderia xenovorans 60000.0 2 PMID:26070669;PMID:26658641 -4.2.1.2 * pelotomaculum thermopropionicum 64200.0 1 PMID:17319878 -4.2.1.2 * rattus norvegicus 200000.0 5 PMID:3812085;PMID:7287666 -4.2.1.2 * saccharolobus solfataricus 170000.0 5 PMID:2124611;PMID:8276121 -4.2.1.2 * saccharomyces cerevisiae 50000.0 1 PMID:1633200;PMID:16717409;PMID:17960613 -4.2.1.2 * schistosoma mansoni 209000.0 1 PMID:33549669 -4.2.1.2 * streptomyces lividans 49000.0 1 PMID:24307253 -4.2.1.2 * sus scrofa 194000.0 2 PMID:14247669;PMID:14247670 -4.2.1.2 * thermus sp. 180000.0 1 PMID:939272 -4.2.1.2 * thermus thermophilus 198000.0 2 PMID:9647666 -4.2.1.20 * agrobacterium tumefaciens 51000.0 2 PMID:9275281 -4.2.1.20 * arabidopsis thaliana 31000.0 2 PMID:7890741 -4.2.1.20 * bacillus subtilis 82000.0 2 PMID:7763866 -4.2.1.20 * escherichia coli 29000.0 1 PMID:12493842 -4.2.1.20 * mycobacterium tuberculosis 50220.0 2 PMID:19430702 -4.2.1.20 * neurospora crassa 74000.0 1 * -4.2.1.20 * pyrococcus furiosus 275000.0 6 PMID:12643278 -4.2.1.20 * saccharolobus solfataricus 134500.0 4 PMID:17115706;PMID:21090805 -4.2.1.20 * saccharomyces cerevisiae 153000.0 3 PMID:391563;PMID:6342605 -4.2.1.20 * salmonella enterica subsp. enterica serovar typhimurium 29000.0 1 PMID:17586773 -4.2.1.20 * serratia marcescens 89000.0 2 PMID:77857 -4.2.1.20 * thermococcus kodakarensis 127000.0 1 PMID:24835339 -4.2.1.20 * thermotoga maritima 140000.0 4 PMID:11756459 -4.2.1.22 * homo sapiens 1330000.0 19 PMID:11524006;PMID:1201041;PMID:19010420;PMID:19073;PMID:19722721;PMID:19733148;PMID:21062078;PMID:21141970;PMID:21262193;PMID:21938399;PMID:23117410;PMID:25044645;PMID:6706953;PMID:681363;PMID:6838228;PMID:7827502 -4.2.1.22 * mus musculus 68000.0 1 PMID:24491430 -4.2.1.22 * nippostrongylus brasiliensis 288000.0 1 PMID:1493873 -4.2.1.22 * pyrococcus furiosus 62800.0 2 PMID:18021800 -4.2.1.22 * rattus norvegicus 290000.0 7 PMID:1493873;PMID:5121611;PMID:6706953;PMID:6838228 -4.2.1.22 * saccharomyces cerevisiae 400000.0 5 PMID:10956046;PMID:21141970;PMID:21938399;PMID:8017103 -4.2.1.22 * thermoplasma acidophilum 38000.0 2 PMID:18021800 -4.2.1.22 * thermoplasma volcanium 36800.0 2 PMID:18021800 -4.2.1.22 * toxoplasma gondii 141000.0 2 PMID:35897745 -4.2.1.22 * trichostrongylus colubriformis 119000.0 1 PMID:1493873 -4.2.1.24 * bos taurus 289000.0 7 PMID:10529243;PMID:3702740;PMID:4052040;PMID:4525290;PMID:4673399;PMID:8439296;PMID:924383 -4.2.1.24 * cereibacter sphaeroides 240000.0 2 PMID:5316770 -4.2.1.24 * escherichia coli 270000.0 2 PMID:8439296;PMID:924383 -4.2.1.24 * homo sapiens 317600.0 10 PMID:12897770;PMID:16377642;PMID:19015748;PMID:3702740;PMID:4052040;PMID:4525290;PMID:457661 -4.2.1.24 * lathyrus oleraceus 309000.0 4 PMID:10913315;PMID:18795796;PMID:9033406 -4.2.1.24 * methanosarcina barkeri 280000.0 2 PMID:10529243;PMID:3702740;PMID:924383 -4.2.1.24 * mus musculus 335000.0 2 PMID:14638682 -4.2.1.24 * neurospora crassa 350000.0 2 PMID:6451221 -4.2.1.24 * plasmodium falciparum 345000.0 2 PMID:14638682 -4.2.1.24 * pseudomonas aeruginosa 280000.0 2 PMID:10529243;PMID:3702740;PMID:924383 -4.2.1.24 * rattus norvegicus 280000.0 1 PMID:21640720 -4.2.1.24 * rhodobacter capsulatus 260000.0 3 PMID:15555082;PMID:4542319 -4.2.1.24 * saccharomyces cerevisiae 275000.0 2 PMID:2204246 -4.2.1.24 * spinacia oleracea 324000.0 3 PMID:1351729;PMID:7210810 -4.2.1.24 * streptomyces yokosukanensis 34800.0 1 PMID:18924404 -4.2.1.24 * tetradesmus obliquus 282000.0 2 PMID:8612634 -4.2.1.24 * toxoplasma gondii 320000.0 3 PMID:20442414 -4.2.1.25 * azospirillum brasilense 128000.0 2 PMID:16950779 -4.2.1.28 * klebsiella oxytoca 207300.0 1 PMID:20712378 -4.2.1.28 * klebsiella pneumoniae 250000.0 25 PMID:375836;PMID:6756401;PMID:7025894;PMID:9344474 -4.2.1.28 * lentilactobacillus diolivorans 210000.0 4 PMID:24078133 -4.2.1.28 * levilactobacillus brevis 180000.0 1 * -4.2.1.28 * propionibacterium freudenreichii 230000.0 1 * -4.2.1.28 * salmonella enterica subsp. enterica serovar typhimurium 207000.0 1 PMID:17516630 -4.2.1.28 * secundilactobacillus collinoides 207000.0 4 PMID:12423373 -4.2.1.3 * bacillus cereus 160000.0 2 PMID:7257;PMID:820347 -4.2.1.3 * bacillus subtilis 150000.0 2 PMID:3110133 -4.2.1.3 * bos taurus 87606.0 3 PMID:16512678;PMID:6699008 -4.2.1.3 * corynebacterium glutamicum 122000.0 3 PMID:20647021 -4.2.1.3 * cucurbita sp. 100000.0 2 * -4.2.1.3 * drosophila melanogaster 100000.0 2 PMID:16679315 -4.2.1.3 * escherichia coli 97500.0 3 PMID:12473114;PMID:1838390 -4.2.1.3 * homo sapiens 83002.0 1 PMID:36738801 -4.2.1.3 * mycobacterium tuberculosis 102000.0 2 PMID:17384188 -4.2.1.3 * paracoccidioides brasiliensis 85700.0 2 PMID:21802049 -4.2.1.3 * rattus rattus 96000.0 4 PMID:12139479 -4.2.1.3 * saccharolobus solfataricus 96000.0 1 PMID:11248696;PMID:12196164 -4.2.1.3 * sulfolobus acidocaldarius 145000.0 2 PMID:11248696;PMID:12196164 -4.2.1.3 * sus scrofa 89000.0 5 PMID:2303429;PMID:5026292;PMID:6349693 -4.2.1.3 * yarrowia lipolytica 68500.0 1 PMID:236289 -4.2.1.30 * citrobacter freundii 198000.0 7 PMID:22821086;PMID:8824629;PMID:9990728 -4.2.1.30 * clostridium pasteurianum 190000.0 4 PMID:9675846;PMID:9990728 -4.2.1.30 * klebsiella pneumoniae 229000.0 28 PMID:10383983;PMID:12230560;PMID:19152074;PMID:22042303;PMID:237191;PMID:4407304;PMID:4989992;PMID:8798396 -4.2.1.30 * limosilactobacillus reuteri 200000.0 2 PMID:16348166 -4.2.1.31 * arthrobacter sp. 90000.0 3 * -4.2.1.31 * ectopseudomonas oleovorans 89000.0 3 PMID:16349034 -4.2.1.31 * oryctolagus cuniculus 69500.0 2 PMID:2990924 -4.2.1.32 * escherichia coli 110500.0 4 PMID:8371115 -4.2.1.32 * pseudomonas putida 145000.0 5 PMID:14342293 -4.2.1.33 * methanocaldococcus jannaschii 46000.0 2 PMID:22326391 -4.2.1.33 * neurospora crassa 90000.0 2 PMID:14087357;PMID:146703 -4.2.1.33 * neurospora sp. 90000.0 1 PMID:3071717;PMID:6456 -4.2.1.33 * saccharomyces cerevisiae 90000.0 1 PMID:3071717;PMID:6456 -4.2.1.33 * salmonella sp. 90000.0 1 PMID:3071717;PMID:6456 -4.2.1.34 * aerobic bacterium 160000.0 1 PMID:893377 -4.2.1.34 * clostridium tetanomorphum 37000.0 1 * -4.2.1.34 * escherichia coli 60105.0 5 PMID:26070669;PMID:26658641 -4.2.1.34 * paraburkholderia xenovorans 60000.0 1 PMID:26070669;PMID:26658641 -4.2.1.36 * methanocaldococcus jannaschii 143000.0 1 PMID:20170198 -4.2.1.36 * penicillium chrysogenum 84490.0 1 PMID:19696106 -4.2.1.39 * achromobacter xylosoxidans 270000.0 3 * -4.2.1.39 * alcaligenes sp. 270000.0 1 PMID:1134357 -4.2.1.39 * clostridium pasteurianum 131000.0 3 PMID:4772682;PMID:7154958 -4.2.1.39 * haloferax volcanii 340000.0 1 PMID:20023024;PMID:27297879 -4.2.1.39 * picrophilus oshimae 340000.0 2 PMID:15509194;PMID:20023024;PMID:27297879 -4.2.1.39 * saccharolobus solfataricus 350000.0 6 PMID:15509194;PMID:18657619;PMID:20023024 -4.2.1.39 * thermoproteus tenax 44040.0 2 PMID:25034432 -4.2.1.40 * acinetobacter baylyi 38000.0 2 PMID:18364348 -4.2.1.41 * acinetobacter baylyi 55000.0 2 PMID:18364348 -4.2.1.41 * agrobacterium fabrum 33526.0 2 PMID:24419616 -4.2.1.41 * agrobacterium tumefaciens 33000.0 1 PMID:24419616 -4.2.1.41 * delftia acidovorans 118000.0 3 PMID:1156361;PMID:237186 -4.2.1.42 * escherichia coli 130000.0 1 PMID:31811683 -4.2.1.43 * azospirillum brasilense 150000.0 5 PMID:16950779;PMID:17565178;PMID:237190;PMID:32697085;PMID:5954356 -4.2.1.43 * roseateles saccharophilus 85000.0 1 PMID:17565178;PMID:237190;PMID:5954356 -4.2.1.45 * yersinia pseudotuberculosis 160000.0 7 PMID:11807280;PMID:15023057;PMID:4343157 -4.2.1.46 * acanthamoeba polyphaga mimivirus 47000.0 2 PMID:20538863 -4.2.1.46 * chlorovirus heliozoae 75000.0 2 PMID:20538863 -4.2.1.46 * escherichia coli 88000.0 4 PMID:4307450;PMID:4309149;PMID:4320607 -4.2.1.46 * mycobacterium tuberculosis 39000.0 1 PMID:26778528 -4.2.1.46 * saccharopolyspora erythraea 60000.0 2 PMID:3170573 -4.2.1.46 * saccharothrix syringae 87600.0 2 PMID:34819927 -4.2.1.46 * salmonella enterica subsp. enterica serovar typhimurium 77000.0 2 PMID:1993076 -4.2.1.46 * streptomyces antibioticus 38000.0 1 * -4.2.1.46 * streptomyces peucetius 54000.0 3 PMID:1588310;PMID:19777229 -4.2.1.46 * streptomyces sp. c5 39000.0 1 PMID:1588310 -4.2.1.47 * burkholderia cepacia 162000.0 1 PMID:23460819 -4.2.1.47 * escherichia coli 250000.0 3 PMID:23404100;PMID:9257704 -4.2.1.47 * homo sapiens 80000.0 5 PMID:10462046;PMID:22645305 -4.2.1.47 * klebsiella pneumoniae 110000.0 2 PMID:7679567;PMID:9893952 -4.2.1.47 * mortierella alpina 140000.0 5 PMID:20035716 -4.2.1.47 * paramecium bursaria chlorella virus-1 87000.0 1 PMID:17974560 -4.2.1.47 * phaseolus vulgaris 120000.0 1 PMID:5047712 -4.2.1.47 * sus scrofa 251000.0 2 PMID:4076184 -4.2.1.48 * mus musculus 146000.0 1 PMID:30003876 -4.2.1.49 * bacillus subtilis 120000.0 2 PMID:25660;PMID:4990470 -4.2.1.49 * comamonas testosteroni 118000.0 2 PMID:25660;PMID:4404600 -4.2.1.49 * felis catus 127000.0 1 PMID:25660 -4.2.1.49 * pseudomonas putida 110000.0 3 PMID:25660;PMID:4404600;PMID:5412708 -4.2.1.49 * salmonella enterica subsp. enterica serovar typhi 61404.0 1 * -4.2.1.49 * trifolium repens 122000.0 2 PMID:1356832 -4.2.1.5 * saccharolobus solfataricus 340700.0 2 PMID:16849334 -4.2.1.50 * citrullus lanatus 58000.0 2 * -4.2.1.51 * acinetobacter calcoaceticus 175000.0 2 PMID:3046943 -4.2.1.51 * amycolatopsis methanolica 150000.0 3 PMID:7592448;PMID:7755580 -4.2.1.51 * archaeoglobus fulgidus 420000.0 4 PMID:19082689 -4.2.1.51 * bacillus subtilis 210000.0 9 PMID:104661;PMID:114523;PMID:3110557 -4.2.1.51 * cupriavidus necator 187000.0 2 PMID:1262315 -4.2.1.51 * escherichia coli 273000.0 7 PMID:20137911;PMID:3037264;PMID:4557843;PMID:7030215 -4.2.1.51 * methanocaldococcus jannaschii 45600.0 3 PMID:17115705 -4.2.1.51 * mycobacterium tuberculosis 134500.0 2 PMID:18384085 -4.2.1.51 * oryza sativa 40000.0 2 PMID:18487352 -4.2.1.51 * pantoea agglomerans 73000.0 2 PMID:1897969 -4.2.1.51 * sphingomonas paucimobilis 135000.0 2 PMID:7399403 -4.2.1.51 * streptococcus mutans 31000.0 1 PMID:24610334 -4.2.1.53 * bifidobacterium animalis subsp. lactis 82000.0 1 * -4.2.1.53 * bifidobacterium breve 67000.0 1 * -4.2.1.53 * elizabethkingia meningoseptica 73487.0 3 PMID:19465645 -4.2.1.53 * lacticaseibacillus rhamnosus 67000.0 1 * -4.2.1.53 * lactiplantibacillus plantarum 67000.0 1 * -4.2.1.53 * lactobacillus acidophilus 67000.0 1 * -4.2.1.53 * lysinibacillus fusiformis 138000.0 4 PMID:22189865 -4.2.1.53 * macrococcoides caseolyticum 136000.0 4 PMID:22203098;PMID:22261174 -4.2.1.53 * staphylococcus aureus 140000.0 1 PMID:31018965 -4.2.1.53 * stenotrophomonas maltophilia 136000.0 3 PMID:22203098;PMID:22261174 -4.2.1.53 * streptococcus pyogenes 67000.0 1 * -4.2.1.54 * megasphaera elsdenii 1000000.0 3 PMID:14292829 -4.2.1.6 * haloferax volcanii 300000.0 1 PMID:32055827 -4.2.1.6 * klebsiella pneumoniae 290000.0 2 PMID:6759856 -4.2.1.6 * mycobacterium butyricum 270000.0 1 PMID:7295736 -4.2.1.6 * mycobacterium sp. 270000.0 1 PMID:6194665 -4.2.1.6 * pseudomonas sp. 245000.0 2 PMID:422572 -4.2.1.65 * lupinus angustifolius 500000.0 1 PMID:4627358 -4.2.1.65 * pseudomonas sp. 1000000.0 2 * -4.2.1.66 * aspergillus niger 40000.0 1 * -4.2.1.66 * exserohilum turcicum 300000.0 1 PMID:20004515 -4.2.1.66 * fusarium lateritium 400000.0 4 PMID:14632988;PMID:8409923 -4.2.1.66 * fusarium oxysporum 300000.0 2 PMID:14632988;PMID:20004515 -4.2.1.66 * fusarium solani 300000.0 2 PMID:14632988 -4.2.1.66 * microdochium sorghi 1000000.0 7 PMID:1382413;PMID:1416986;PMID:14632988;PMID:20004515 -4.2.1.66 * plenodomus lingam 160000.0 2 PMID:14632988 -4.2.1.66 * stemphylium loti 300000.0 1 PMID:20004515 -4.2.1.68 * aureobasidium pullulans 104000.0 2 * -4.2.1.69 * albifimbria verrucaria 25000.0 1 * -4.2.1.7 * escherichia coli 53000.0 1 PMID:3038546 -4.2.1.70 * escherichia coli 31000.0 1 PMID:2981810 -4.2.1.70 * mus musculus 46610.0 1 PMID:10094309 -4.2.1.70 * saccharomyces cerevisiae 63200.0 2 PMID:9585540;PMID:9671058 -4.2.1.70 * salmonella enterica subsp. enterica serovar typhimurium 50000.0 1 PMID:370771 -4.2.1.73 * eriosoma lanigerum 120000.0 1 * -4.2.1.74 * sus scrofa 81000.0 2 PMID:8323290 -4.2.1.75 * arabidopsis thaliana 34000.0 2 PMID:18042043 -4.2.1.75 * bacillus subtilis 41500.0 3 PMID:7628476 -4.2.1.75 * escherichia coli 29000.0 3 PMID:2557837 -4.2.1.75 * euglena gracilis 38500.0 2 PMID:3936481 -4.2.1.75 * homo sapiens 37000.0 8 PMID:12196144;PMID:15496592;PMID:18004775;PMID:21570665;PMID:24925316;PMID:3805019 -4.2.1.75 * rattus norvegicus 42000.0 4 PMID:17763925;PMID:3138984;PMID:6466301 -4.2.1.76 * acanthamoeba polyphaga mimivirus 100000.0 4 PMID:20538863 -4.2.1.76 * botrytis cinerea 140000.0 2 PMID:22102281 -4.2.1.76 * chlorovirus heliozoae 75000.0 2 PMID:20538863 -4.2.1.76 * pyricularia grisea 140000.0 2 PMID:22102281 -4.2.1.76 * trichomonas vaginalis 91000.0 1 PMID:36498914 -4.2.1.77 * azospirillum brasilense 87000.0 3 PMID:24649405 -4.2.1.79 * corynebacterium glutamicum 55000.0 1 PMID:20924576 -4.2.1.79 * escherichia coli 54000.0 2 PMID:11782506;PMID:12473114 -4.2.1.79 * yarrowia lipolytica 79000.0 2 * -4.2.1.8 * streptococcus suis 80000.0 2 PMID:19617363 -4.2.1.8 * thermoplasma acidophilum 225000.0 1 * -4.2.1.80 * escherichia coli 28000.0 1 PMID:9492273 -4.2.1.80 * escherichia coli k-12 151000.0 3 PMID:20053352 -4.2.1.80 * paraburkholderia xenovorans 221000.0 2 PMID:15691330 -4.2.1.80 * pseudomonas putida 28000.0 1 PMID:9492273 -4.2.1.80 * pseudomonas sp. 28040.0 2 PMID:10836749;PMID:9299451 -4.2.1.81 * cereibacter sphaeroides 158000.0 2 PMID:6978882 -4.2.1.81 * pseudomonas sp. 78000.0 3 PMID:7107563 -4.2.1.82 * escherichia coli 70000.0 1 PMID:26083940 -4.2.1.82 * haloferax volcanii 340000.0 3 PMID:19584053 -4.2.1.83 * phytopseudomonas straminea 72000.0 5 PMID:17284837;PMID:3985968;PMID:6841354 -4.2.1.83 * sphingomonas paucimobilis 69500.0 2 PMID:11092855 -4.2.1.84 * agrobacterium tumefaciens 102000.0 2 PMID:11607511 -4.2.1.84 * albifimbria verrucaria 27700.0 1 PMID:8987584 -4.2.1.84 * aplysina cavernicola 242000.0 4 PMID:23966036 -4.2.1.84 * arthrobacter sp. 420000.0 3 PMID:1527703 -4.2.1.84 * bacillus smithii 110000.0 3 PMID:16511211 -4.2.1.84 * bacillus sp. (in: firmicutes) 110000.0 1 PMID:9783183 -4.2.1.84 * brevibacterium sp. 95000.0 13 PMID:1527703;PMID:3768004;PMID:8797859 -4.2.1.84 * caldalkalibacillus thermarum 102400.0 2 PMID:33749895 -4.2.1.84 * comamonas testosteroni 90000.0 8 PMID:12729727;PMID:15668757;PMID:17267045 -4.2.1.84 * corynebacterium pseudodiphtheriticum 80000.0 3 * -4.2.1.84 * corynebacterium sp. 61400.0 2 * -4.2.1.84 * monosiga brevicollis 55000.0 1 PMID:27693250 -4.2.1.84 * prescottella equi 24000.0 2 PMID:19662400 -4.2.1.84 * pseudomonas chlororaphis 100000.0 2 PMID:3830164 -4.2.1.84 * pseudomonas putida 94000.0 6 PMID:21473592;PMID:9154927;PMID:9457799 -4.2.1.84 * rhodococcus erythropolis 92300.0 5 * -4.2.1.84 * rhodococcus rhodochrous 530000.0 15 PMID:1527703;PMID:2013281;PMID:23100776;PMID:28644864;PMID:3421954;PMID:8987584 -4.2.1.84 * rhodococcus sp. (in: high g+c gram-positive bacteria) 364000.0 17 PMID:10850812;PMID:1527703;PMID:17330219;PMID:17635193;PMID:2920826 -4.2.1.85 * eubacterium barkeri 153000.0 1 PMID:6489933 -4.2.1.88 * arthrobacter synephrinum 156000.0 2 PMID:3729420 -4.2.1.9 * aspergillus fumigatus 65000.0 1 PMID:23028460 -4.2.1.9 * escherichia coli 125000.0 2 PMID:16567425;PMID:8325851 -4.2.1.9 * mycobacterium tuberculosis 155000.0 2 PMID:20864475 -4.2.1.9 * saccharolobus solfataricus 66000.0 2 PMID:16567425;PMID:8325851 -4.2.1.9 * spinacia oleracea 110000.0 3 PMID:2831190 -4.2.1.90 * haloferax volcanii 349000.0 1 PMID:30707467 -4.2.1.91 * pantoea agglomerans 73000.0 2 PMID:1897969 -4.2.1.91 * petunia x hybrida 47300.0 3 PMID:20215586 -4.2.1.91 * pseudomonas aeruginosa 72000.0 8 PMID:1733946;PMID:8515238 -4.2.1.92 * arabidopsis thaliana 58000.0 1 PMID:20159849 -4.2.1.92 * aspergillus terreus 133000.0 1 PMID:23479731 -4.2.1.92 * gracilariopsis lemaneiformis 220000.0 2 PMID:8342944 -4.2.1.92 * lonicera japonica 59200.0 1 PMID:18167030 -4.2.1.92 * nostoc punctiforme 45000.0 1 PMID:24659780 -4.2.1.92 * parthenium argentatum 53000.0 1 PMID:19747698 -4.2.1.92 * physcomitrium patens 53500.0 2 PMID:19851025 -4.2.1.92 * solanum melongena 293000.0 1 * -4.2.1.93 * arabidopsis thaliana 132700.0 2 PMID:24706747 -4.2.1.94 * bipolaris oryzae 23000.0 2 PMID:14716498;PMID:15056895;PMID:15469312 -4.2.1.94 * phaeococcomyces sp. 63000.0 1 * -4.2.1.94 * pyricularia grisea 60000.0 2 PMID:14716498;PMID:15056895;PMID:15469312;PMID:8355286 -4.2.1.94 * pyricularia oryzae 21000.0 1 PMID:14716498;PMID:15056895;PMID:15469312 -4.2.1.95 * fusarium phaseoli 175000.0 3 PMID:1521768 -4.2.1.95 * fusarium solani 75000.0 1 PMID:29420618 -4.2.1.96 * homo sapiens 45000.0 4 PMID:7635153;PMID:8444860;PMID:9698371 -4.2.1.96 * rattus norvegicus 46000.0 5 PMID:8444860;PMID:9698371 -4.2.1.96 * toxoplasma gondii 46000.0 2 PMID:18215430 -4.2.1.98 * eubacterium sp. 326000.0 8 PMID:4052439 -4.2.1.99 * yarrowia lipolytica 69000.0 1 * -4.2.2.1 * bacillus sp. (in: firmicutes) 145000.0 2 PMID:36524342 -4.2.2.1 * clostridium perfringens 114000.0 1 PMID:10675584 -4.2.2.1 * cutibacterium acnes 126000.0 3 PMID:10675584;PMID:43356 -4.2.2.1 * homo sapiens 55000.0 2 PMID:20586096 -4.2.2.1 * mus musculus 47000.0 2 PMID:20586096 -4.2.2.1 * staphylococcus aureus 92000.0 3 PMID:10675584;PMID:4218146;PMID:4782529 -4.2.2.1 * streptococcus agalactiae 121000.0 7 PMID:10675584;PMID:10739920;PMID:12130645;PMID:12659938;PMID:16854993 -4.2.2.1 * streptococcus dysgalactiae subsp. equisimilis 110000.0 2 * -4.2.2.1 * streptococcus equi subsp. equi 4047 42000.0 1 PMID:19202092 -4.2.2.1 * streptococcus pneumoniae 107000.0 6 PMID:10675584;PMID:12719417;PMID:9631519 -4.2.2.1 * streptococcus pyogenes 75000.0 1 * -4.2.2.1 * streptococcus pyogenes phage h10403 110000.0 2 PMID:16415347;PMID:18849564 -4.2.2.1 * streptococcus pyogenes phage h4489a 120000.0 4 PMID:12071858;PMID:24721581 -4.2.2.1 * streptococcus sp. 70000.0 2 PMID:9365 -4.2.2.1 * streptococcus suis 130000.0 2 PMID:15120159 -4.2.2.1 * thermasporomyces composti 90000.0 2 PMID:33038404 -4.2.2.10 * aspergillus ficuum 31600.0 1 * -4.2.2.10 * aspergillus flavus 50000.0 2 PMID:12882638;PMID:17970283;PMID:24455866 -4.2.2.10 * aspergillus japonicus 50000.0 2 PMID:12882638;PMID:17970283;PMID:24455866 -4.2.2.10 * aspergillus niger 45000.0 4 PMID:12418964;PMID:24863479 -4.2.2.10 * aspergillus oryzae 48000.0 4 PMID:16233008 -4.2.2.10 * aspergillus sojae 32000.0 2 * -4.2.2.10 * aspergillus terricola 35000.0 1 PMID:19089648 -4.2.2.10 * bacillus cereus 64000.0 1 * -4.2.2.10 * bacillus pumilus 25000.0 1 * -4.2.2.10 * bacillus sp. (in: firmicutes) 106000.0 3 * -4.2.2.10 * colletotrichum lindemuthianum 37400.0 4 PMID:22151976 -4.2.2.10 * cystofilobasidium capitatum 42000.0 1 * -4.2.2.10 * erwinia aroidea 32000.0 1 * -4.2.2.10 * fusarium oxysporum 18000.0 2 * -4.2.2.10 * globisporangium splendens 23000.0 1 * -4.2.2.10 * oidiodendron echinulatum 47000.0 2 PMID:22359214 -4.2.2.10 * pectobacterium aroidearum 28000.0 1 * -4.2.2.10 * pectobacterium carotovorum 28000.0 1 * -4.2.2.10 * penicillium canescens 38000.0 3 PMID:17573712 -4.2.2.10 * penicillium citrinum 31000.0 1 PMID:19747102 -4.2.2.10 * penicillium expansum 36500.0 2 PMID:24420203 -4.2.2.10 * penicillium griseoroseum 105000.0 1 PMID:18030511 -4.2.2.10 * penicillium italicum 34000.0 3 PMID:2013333 -4.2.2.10 * penicillium oxalicum 50000.0 1 PMID:12882638;PMID:17970283;PMID:24455866 -4.2.2.10 * penicillium velutinum 42000.0 1 * -4.2.2.10 * pseudomonas fluorescens 32000.0 2 PMID:3115958 -4.2.2.10 * pseudomonas marginalis 34000.0 2 PMID:2013333 -4.2.2.10 * rhizoctonia solani 35000.0 2 PMID:19089648 -4.2.2.10 * rhizopus arrhizus 31000.0 1 PMID:19747102 -4.2.2.10 * selenicereus monacanthus 34200.0 2 * -4.2.2.10 * shouchella clausii 35880.0 2 PMID:22695924 -4.2.2.10 * talaromyces purpureogenus 45000.0 1 PMID:12418964;PMID:24863479 -4.2.2.10 * thanatephorus cucumeris 39000.0 1 PMID:15008348 -4.2.2.11 * agarivorans sp. 31000.0 1 PMID:18417222 -4.2.2.11 * alteromonas sp. 33900.0 2 PMID:11272816 -4.2.2.11 * aspergillus oryzae 50000.0 2 * -4.2.2.11 * bacillus sp. (in: firmicutes) 41000.0 2 PMID:9721637 -4.2.2.11 * corynebacterium sp. 28600.0 3 PMID:11018131;PMID:9491925 -4.2.2.11 * enterobacter cloacae 38000.0 2 PMID:7772828 -4.2.2.11 * flavobacterium sp. 63000.0 1 * -4.2.2.11 * isoptericola halotolerans 28000.0 2 PMID:24053829 -4.2.2.11 * klebsiella aerogenes 31600.0 2 PMID:2673122 -4.2.2.11 * lambis sp. aab-2014 31000.0 2 * -4.2.2.11 * microbulbifer sp. alw1 26000.0 1 PMID:26686613 -4.2.2.11 * pseudoalteromonas distincta 32000.0 1 PMID:11018131 -4.2.2.11 * pseudoalteromonas sp. 32000.0 1 PMID:21339950 -4.2.2.11 * pseudomonas aeruginosa 25000.0 1 PMID:12876365 -4.2.2.11 * pseudomonas fluorescens 60250.0 3 PMID:21170604 -4.2.2.11 * pseudomonas sp. 45500.0 3 PMID:22145710 -4.2.2.11 * saccharophagus degradans 81600.0 3 PMID:22281843;PMID:22391735 -4.2.2.11 * saccharophagus sp. myt-1 43000.0 2 PMID:23676907 -4.2.2.11 * sargassum sp. 38000.0 1 PMID:11018131 -4.2.2.11 * sphingobacterium multivorum 43000.0 2 * -4.2.2.11 * sphingomonas sp. 80000.0 4 PMID:16511020;PMID:21826589 -4.2.2.11 * stenotrophomonas maltophilia 47800.0 1 PMID:22805784 -4.2.2.11 * uncultured bacterium 77500.0 1 PMID:22072436 -4.2.2.11 * vibrio harveyi 57000.0 1 PMID:11018131 -4.2.2.11 * vibrio sp. 54426.0 7 PMID:11018131;PMID:19941025;PMID:23299986 -4.2.2.11 * vibrio splendidus 36500.0 2 PMID:25556193 -4.2.2.11 * zobellia galactanivorans 69500.0 3 PMID:23782694 -4.2.2.12 * bacillus sp. (in: firmicutes) 75000.0 1 PMID:9758797 -4.2.2.12 * microbacterium sp. 110000.0 1 PMID:25054177 -4.2.2.12 * paenibacillus alginolyticus 100000.0 2 PMID:10347025;PMID:10966413 -4.2.2.12 * uncultured bacterium 33000.0 1 PMID:16348550 -4.2.2.13 * gracilaria gracilis 117000.0 1 PMID:20004890 -4.2.2.13 * gracilariopsis chorda 100000.0 1 PMID:10564758 -4.2.2.13 * gracilariopsis lemaneiformis 116700.0 3 PMID:7766642;PMID:8461323 -4.2.2.14 * sinorhizobium meliloti 20000.0 1 PMID:11679345 -4.2.2.14 * trichoderma reesei 27000.0 1 PMID:18978091 -4.2.2.14 * trichoderma sp. 27000.0 1 PMID:16025327 -4.2.2.15 * macrobdella decora 84000.0 1 PMID:8034634 -4.2.2.16 * microbacterium sp. 54000.0 2 PMID:11522362;PMID:12074698 -4.2.2.16 * paenarthrobacter nicotinovorans 52000.0 2 * -4.2.2.16 * paenarthrobacter ureafaciens 96000.0 2 PMID:10899545 -4.2.2.17 * arthrobacter 40000.0 1 PMID:7764697 -4.2.2.17 * arthrobacter globiformis 46000.0 3 PMID:8534968 -4.2.2.17 * nocardioidaceae bacterium broad-1 58000.0 1 * -4.2.2.17 * nocardioides sp. 50000.0 1 * -4.2.2.17 * paenarthrobacter ureafaciens 61000.0 4 PMID:12889813 -4.2.2.17 * streptomyces davaonensis 12500.0 1 PMID:27475232 -4.2.2.18 * arthrobacter globiformis 50000.0 5 PMID:14646096;PMID:29476401;PMID:7764697 -4.2.2.18 * arthrobacter pascens 79000.0 1 PMID:29476401 -4.2.2.18 * arthrobacter sp. 145000.0 10 PMID:23499085;PMID:29476401;PMID:7764697;PMID:9028036 -4.2.2.18 * arthrobacter sp. 161mfsha2.1 125000.0 2 PMID:25794105;PMID:29476401 -4.2.2.18 * arthrobacter sp. a-6 145000.0 1 PMID:29476401 -4.2.2.18 * arthrobacter sp. h65-7 100000.0 1 PMID:29476401 -4.2.2.18 * arthrobacter sp. l68-1 73000.0 1 PMID:29476401 -4.2.2.18 * aspergillus foetidus 78000.0 1 PMID:24031675 -4.2.2.18 * bacillus sp. (in: firmicutes) 88000.0 3 PMID:18051351 -4.2.2.18 * bacillus sp. snu-7 88000.0 1 PMID:29476401 -4.2.2.18 * flavobacterium sp. lc-413 45000.0 1 PMID:29476401 -4.2.2.18 * leifsonia sp. t88-4 74000.0 2 PMID:29476401 -4.2.2.18 * microbacterium sp. s48-1 46000.0 1 PMID:7764697 -4.2.2.18 * paenarthrobacter aurescens 40000.0 3 PMID:20933390;PMID:29476401 -4.2.2.18 * paenarthrobacter ilicis 50000.0 2 PMID:29476401 -4.2.2.18 * paenarthrobacter ureafaciens 80000.0 3 PMID:20933390;PMID:29476401 -4.2.2.18 * pseudarthrobacter chlorophenolicus 125000.0 1 PMID:29476401 -4.2.2.18 * streptomyces sp. 70000.0 2 PMID:7764697 -4.2.2.18 * thermothielavioides terrestris 72000.0 1 PMID:24031675 -4.2.2.19 * pedobacter heparinus 55200.0 3 PMID:10618199;PMID:11500043;PMID:8526872 -4.2.2.2 * actinomadura keratinilytica 34000.0 1 * -4.2.2.2 * alkalihalobacillus alcalophilus 35000.0 1 PMID:18445524 -4.2.2.2 * aspergillus nidulans 40000.0 1 * -4.2.2.2 * aspergillus niger 42600.0 6 PMID:17655960 -4.2.2.2 * aspergillus parasiticus 41000.0 1 PMID:32109469 -4.2.2.2 * bacillus licheniformis 33400.0 1 * -4.2.2.2 * bacillus pumilus 37556.0 4 PMID:16168510;PMID:18445524;PMID:20596756 -4.2.2.2 * bacillus sp. (in: firmicutes) 70000.0 14 PMID:10052123;PMID:10216231;PMID:10691990;PMID:10923781;PMID:11193403;PMID:18445524;PMID:19202269;PMID:20467237 -4.2.2.2 * bacillus subtilis 46000.0 12 PMID:15892742;PMID:20467237;PMID:2126210;PMID:21915717;PMID:23510095;PMID:7764545;PMID:8262178 -4.2.2.2 * bacteroides thetaiotaomicron 74000.0 1 PMID:3968032 -4.2.2.2 * cellvibrio japonicus 68500.0 2 PMID:11256960 -4.2.2.2 * chondrostereum purpureum 48000.0 1 * -4.2.2.2 * clonostachys rosea 37000.0 1 PMID:30404596 -4.2.2.2 * clostridium cellulovorans 42000.0 1 PMID:20467237 -4.2.2.2 * colletotrichum gloeosporioides 40000.0 2 PMID:8012046;PMID:9602123 -4.2.2.2 * dickeya chrysanthemi 44000.0 6 PMID:35534597;PMID:8012046;PMID:9098045;PMID:9602123 -4.2.2.2 * erwinia aroidea 38000.0 1 * -4.2.2.2 * fusarium solani 23000.0 1 PMID:8806739 -4.2.2.2 * fusarium verticillioides 12100.0 3 * -4.2.2.2 * georgenia muralis 75000.0 1 PMID:25209746 -4.2.2.2 * gossypium hirsutum 45000.0 1 PMID:20131110 -4.2.2.2 * heterodera schachtii 26020.0 2 PMID:20507498 -4.2.2.2 * hevea brasiliensis 43900.0 1 PMID:19144526 -4.2.2.2 * massilia eurypsychrophila 34700.0 1 PMID:31028436 -4.2.2.2 * mrakia frigida 38000.0 2 PMID:15892742 -4.2.2.2 * musa acuminata 44000.0 2 PMID:16554075 -4.2.2.2 * niveispirillum irakense 44400.0 1 * -4.2.2.2 * nocardiopsis sp. 54000.0 1 * -4.2.2.2 * paenibacillus lactis 44000.0 1 PMID:35534597 -4.2.2.2 * paenibacillus macerans 46000.0 3 * -4.2.2.2 * paenibacillus polymyxa 45300.0 3 PMID:30373112;PMID:31234557 -4.2.2.2 * pectobacterium carotovorum 44000.0 5 PMID:3040692;PMID:7756691 -4.2.2.2 * penicillium occitanis (nom. inval.) 39000.0 1 * -4.2.2.2 * pseudonocardia sp. 10000000.0 3 PMID:7486993 -4.2.2.2 * streptomyces coelicolor 49900.0 2 PMID:18317750 -4.2.2.2 * streptomyces nitrosporeus 41000.0 2 PMID:8012046 -4.2.2.2 * streptomyces sp. 35000.0 2 PMID:22278674 -4.2.2.2 * streptomyces thermocarboxydus 28000.0 4 PMID:20139595 -4.2.2.2 * thermoanaerobacter italicus 158000.0 4 PMID:9680298 -4.2.2.2 * thermobifida fusca 56000.0 2 PMID:3584069 -4.2.2.2 * thermoclostridium stercorarium 135171.0 4 PMID:16306696;PMID:16556983 -4.2.2.2 * thermotoga maritima 43000.0 1 PMID:19459327 -4.2.2.2 * xanthomonas campestris 38000.0 3 PMID:18317750;PMID:22983714 -4.2.2.21 * bacteroides thetaiotaomicron 108000.0 2 PMID:6630153 -4.2.2.21 * pedobacter heparinus 150000.0 1 PMID:5647268 -4.2.2.21 * proteus vulgaris 150000.0 8 PMID:15691229;PMID:18849565;PMID:19884507;PMID:5647268 -4.2.2.22 * aspergillus nidulans 40000.0 1 * -4.2.2.22 * bacillus licheniformis 36000.0 2 PMID:14673544 -4.2.2.22 * clostridium cellulovorans 42000.0 1 * -4.2.2.22 * thermotoga maritima 152000.0 2 PMID:12443532 -4.2.2.23 * aspergillus aculeatus 57000.0 3 PMID:7961884;PMID:9576783 -4.2.2.23 * aspergillus sojae 55000.0 1 PMID:7961884 -4.2.2.23 * bacillus subtilis 68000.0 5 PMID:16682770;PMID:17449691;PMID:19193638 -4.2.2.23 * cellvibrio japonicus 93415.0 1 PMID:11256961 -4.2.2.23 * dickeya chrysanthemi 62000.0 2 PMID:12591882 -4.2.2.23 * ruminiclostridium cellulolyticum 75000.0 1 PMID:12896991 -4.2.2.24 * bacillus subtilis 687544.0 4 PMID:17449691;PMID:19193638 -4.2.2.25 * bacillus sp. (in: firmicutes) 260000.0 4 PMID:14759609;PMID:9056228 -4.2.2.25 * geobacillus stearothermophilus 480000.0 5 PMID:16482399;PMID:20469643 -4.2.2.25 * unidentified microorganism 140000.0 1 PMID:8919816 -4.2.2.26 * saccharophagus degradans 81600.0 2 PMID:22281843 -4.2.2.26 * shewanella sp. 82000.0 1 PMID:25335746 -4.2.2.26 * sphingomonas sp. 86543.0 3 PMID:10913091 -4.2.2.26 * zobellia galactanivorans 163000.0 1 PMID:34184062 -4.2.2.27 * aspergillus giganteus 71000.0 2 PMID:25610636 -4.2.2.28 * fusarium oxysporum 55000.0 1 PMID:34303708 -4.2.2.29 * escherichia coli 65000.0 1 PMID:357 -4.2.2.3 * agarivorans sp. 32300.0 4 PMID:19002649;PMID:19941025 -4.2.2.3 * agrobacterium tumefaciens 350000.0 4 PMID:16545947;PMID:20507980 -4.2.2.3 * alginovibrio aquatilis 110000.0 1 PMID:11018131 -4.2.2.3 * alteromonas sp. 33900.0 2 PMID:11272816 -4.2.2.3 * aplysia kurodai 33000.0 6 PMID:20708706;PMID:21689718 -4.2.2.3 * aspergillus oryzae 50000.0 4 * -4.2.2.3 * azotobacter chroococcum 46000.0 3 PMID:10049370;PMID:11018131 -4.2.2.3 * azotobacter phage a31 42000.0 1 PMID:11018131 -4.2.2.3 * azotobacter vinelandii 50000.0 5 PMID:13144;PMID:19482920;PMID:9683471 -4.2.2.3 * azotobacter vinelandii phage 35000.0 1 PMID:11018131;PMID:13144 -4.2.2.3 * bacillus sp. (in: firmicutes) 41000.0 3 PMID:11018131;PMID:9721637 -4.2.2.3 * chlorella virus 39000.0 1 PMID:10547443 -4.2.2.3 * cobetia marina 39000.0 1 * -4.2.2.3 * haliotis discus hannai 32000.0 3 PMID:16697989;PMID:17536832;PMID:21339950 -4.2.2.3 * haliotis iris 34000.0 1 * -4.2.2.3 * haliotis tuberculata 34000.0 1 PMID:11018131 -4.2.2.3 * isoptericola halotolerans 28000.0 1 PMID:24053829 -4.2.2.3 * littorina brevicula 35000.0 5 PMID:22940178 -4.2.2.3 * littorina sp. 40000.0 1 * -4.2.2.3 * microbulbifer sp. alw1 26000.0 1 PMID:26686613 -4.2.2.3 * nitratiruptor sp. sb155-2 27000.0 1 PMID:27231344 -4.2.2.3 * omphalius rusticus 34000.0 1 * -4.2.2.3 * paradendryphiella salina 36000.0 2 PMID:9145523 -4.2.2.3 * photobacterium sp. 30000.0 1 PMID:11018131 -4.2.2.3 * pseudoalteromonas distincta 32000.0 2 PMID:11018131 -4.2.2.3 * pseudoalteromonas sp. 58000.0 4 PMID:12523649;PMID:16697989;PMID:17536832;PMID:19898554;PMID:21339950 -4.2.2.3 * pseudomonas aeruginosa 43500.0 4 PMID:11018131;PMID:15136569;PMID:22691793 -4.2.2.3 * pseudomonas alginovora 24000.0 1 PMID:11018131 -4.2.2.3 * pseudomonas fluorescens 60250.0 6 PMID:21170604 -4.2.2.3 * pseudomonas sp. 94000.0 4 PMID:7896072 -4.2.2.3 * pseudomonas syringae 40000.0 1 PMID:11029455 -4.2.2.3 * saccharophagus degradans 81600.0 3 PMID:22281843;PMID:22391735 -4.2.2.3 * sphingomonas sp. 85000.0 15 PMID:10833394;PMID:10913091;PMID:11018131;PMID:15090531;PMID:16233753;PMID:21826589 -4.2.2.3 * stenotrophomonas maltophilia 47800.0 1 PMID:22805784 -4.2.2.3 * streptomyces sp. 32000.0 3 PMID:16697989;PMID:17536832;PMID:18553118;PMID:20640446;PMID:21339950 -4.2.2.3 * turbo cornutus 32000.0 3 PMID:11018131;PMID:15090531 -4.2.2.3 * uncultured marine bacterium 100000.0 3 PMID:16346509 -4.2.2.3 * undaria pinnatifida 74000.0 1 PMID:11018131 -4.2.2.3 * vibrio alginolyticus 47000.0 1 PMID:11018131 -4.2.2.3 * vibrio sinaloensis 29000.0 1 PMID:11018131 -4.2.2.3 * vibrio sp. 62500.0 10 PMID:16802207;PMID:16953302;PMID:19941025;PMID:23299986 -4.2.2.3 * vibrio splendidus 68200.0 2 PMID:25556193 -4.2.2.3 * zobellia galactanivorans 69500.0 3 PMID:23782694 -4.2.2.5 * arthrobacter sp. mat3885 80000.0 1 PMID:25912370 -4.2.2.5 * bacteroides stercoris 170000.0 3 PMID:12071957;PMID:18226546 -4.2.2.5 * flavobacterium columnare 42600.0 1 * -4.2.2.5 * paenarthrobacter aurescens 79840.0 3 PMID:1225917;PMID:15003453 -4.2.2.5 * pedobacter heparinus 78030.0 3 PMID:10618199;PMID:11500043;PMID:8526872 -4.2.2.5 * serratia marcescens 71000.0 2 PMID:15928855 -4.2.2.6 * dickeya chrysanthemi 44124.0 1 PMID:10383957 -4.2.2.7 * aspergillus flavus 24000.0 3 PMID:19214796 -4.2.2.7 * bacteroides stercoris 85400.0 3 PMID:10920269;PMID:15607027;PMID:19566715 -4.2.2.7 * niallia circulans 111200.0 2 PMID:12092842;PMID:12400686 -4.2.2.7 * pedobacter heparinus 85000.0 5 PMID:16844434;PMID:20404324;PMID:3968088;PMID:6476820 -4.2.2.7 * prevotella heparinolytica 63000.0 1 PMID:3384902 -4.2.2.7 * sphingobacterium sp. 75670.0 2 PMID:14561722 -4.2.2.8 * bacteroides stercoris 74930.0 1 PMID:19908038 -4.2.2.9 * acrophialophora nainiana 35000.0 1 PMID:16337707 -4.2.2.9 * dickeya chrysanthemi 76938.0 1 PMID:10049400 -4.2.2.9 * pectobacterium carotovorum 76000.0 1 * -4.2.2.9 * streptomyces massasporeus 54000.0 1 * -4.2.2.9 * streptomyces nitrosporeus 39000.0 3 * -4.2.3.1 * arabidopsis thaliana 110000.0 2 PMID:10429206;PMID:8706836;PMID:9748328 -4.2.3.1 * corynebacterium glutamicum 53000.0 2 PMID:8074505 -4.2.3.1 * escherichia coli 48000.0 1 PMID:6316258 -4.2.3.1 * lathyrus oleraceus 190000.0 1 * -4.2.3.1 * methanosarcina acetivorans c2a 135000.0 2 PMID:19761441 -4.2.3.1 * oryza sativa 57200.0 1 * -4.2.3.10 * lavandula pedunculata 45000.0 1 PMID:24943828 -4.2.3.10 * lavandula viridis 45000.0 1 PMID:24943828 -4.2.3.101 * zea mays 66000.0 2 PMID:15075399 -4.2.3.104 * zingiber zerumbet 64500.0 1 PMID:18273640 -4.2.3.105 * solanum lycopersicum 70652.0 1 PMID:21813655 -4.2.3.106 * antirrhinum majus 66724.0 1 PMID:12724546 -4.2.3.106 * arabidopsis thaliana 69278.0 2 PMID:10700382;PMID:12624761 -4.2.3.106 * citrus unshiu 71200.0 2 * -4.2.3.106 * litsea cubeba 63000.0 2 * -4.2.3.106 * lotus japonicus 68800.0 1 PMID:15310830 -4.2.3.107 * picea abies 71912.0 1 PMID:12602896 -4.2.3.107 * salvia stenophylla 69700.0 1 PMID:12591260 -4.2.3.108 * arabidopsis thaliana 60000.0 1 PMID:15299125 -4.2.3.108 * lavandula x intermedia 68500.0 2 PMID:22592779 -4.2.3.108 * nicotiana suaveolens 64550.0 1 PMID:17611797 -4.2.3.108 * salvia officinalis 72000.0 3 PMID:8117108;PMID:9614092 -4.2.3.108 * streptomyces clavuligerus 40000.0 1 PMID:21726035 -4.2.3.109 * arabidopsis thaliana 60000.0 1 PMID:15299125 -4.2.3.109 * conocephalum conicum 65000.0 1 PMID:9747540 -4.2.3.11 * origanum majorana 56000.0 1 PMID:3401015 -4.2.3.110 * litsea cubeba 67400.0 2 * -4.2.3.110 * salvia officinalis 68490.0 1 PMID:9614092 -4.2.3.112 * santalum album 66000.0 1 PMID:18541135 -4.2.3.113 * lavandula angustifolia 70300.0 1 PMID:17662687 -4.2.3.113 * picea abies 71912.0 1 PMID:12602896 -4.2.3.114 * salvia officinalis 68490.0 1 PMID:9614092 -4.2.3.114 * thymus caespititius 66268.0 1 PMID:23624978 -4.2.3.114 * thymus vulgaris 96000.0 3 PMID:1897973;PMID:736574 -4.2.3.116 * salvia officinalis 95000.0 1 PMID:6693393 -4.2.3.117 * abies grandis 70750.0 1 PMID:10441373 -4.2.3.117 * salvia officinalis 95000.0 1 PMID:6693393 -4.2.3.118 * streptomyces coelicolor 150000.0 4 PMID:18563898;PMID:22455514 -4.2.3.118 * streptomyces lasalocidi 52400.0 1 PMID:18492804 -4.2.3.119 * abies grandis 71500.0 5 PMID:10441373;PMID:1731633;PMID:1898071;PMID:9268308 -4.2.3.119 * gossypium hirsutum 69400.0 1 PMID:24184450 -4.2.3.119 * pinus taeda 65000.0 2 PMID:10562434;PMID:12623076 -4.2.3.119 * salvia officinalis 95000.0 1 PMID:6693393 -4.2.3.12 * bombyx mori 87000.0 3 PMID:8304108 -4.2.3.12 * drosophila melanogaster 83000.0 3 PMID:2110003 -4.2.3.12 * homo sapiens 97000.0 18 PMID:1308853;PMID:1734893;PMID:1939130;PMID:2651122;PMID:3511907;PMID:3536512;PMID:7493990;PMID:8216273;PMID:8304107;PMID:8307017 -4.2.3.12 * mortierella alpina 21000.0 1 PMID:21852350 -4.2.3.12 * rattus norvegicus 83000.0 5 PMID:1939130;PMID:2651122;PMID:7563095;PMID:8216273;PMID:8307017 -4.2.3.12 * salmo salar 68000.0 4 PMID:1308853;PMID:1734893;PMID:1939130;PMID:2651122;PMID:8216273 -4.2.3.120 * abies grandis 71500.0 4 PMID:1731633;PMID:1898071;PMID:9268308 -4.2.3.120 * gossypium hirsutum 69400.0 1 PMID:24184450 -4.2.3.120 * pinus taeda 65000.0 1 PMID:10562434 -4.2.3.120 * salvia officinalis 95000.0 1 PMID:6693393 -4.2.3.121 * lavandula angustifolia 70300.0 1 PMID:17662687 -4.2.3.121 * lavandula pedunculata 45000.0 1 PMID:24943828 -4.2.3.121 * lavandula viridis 45000.0 1 PMID:24943828 -4.2.3.121 * pinus taeda 65000.0 2 PMID:10562434;PMID:12623076 -4.2.3.121 * salvia officinalis 100000.0 2 PMID:2644252;PMID:6693393 -4.2.3.123 * persicaria minor 65000.0 3 PMID:24678279;PMID:28265494;PMID:32059132 -4.2.3.124 * niallia circulans 77000.0 12 PMID:10344560;PMID:10470681;PMID:14750780;PMID:20530911 -4.2.3.124 * streptomyces lividans 45000.0 1 PMID:15928851 -4.2.3.13 * gossypium arboreum 64120.0 4 PMID:19489610;PMID:8554317;PMID:8904844 -4.2.3.13 * gossypium hirsutum 64000.0 2 PMID:15849309;PMID:8728715 -4.2.3.13 * helianthus annuus 64200.0 2 PMID:19580670 -4.2.3.132 * pinus taeda 97500.0 1 PMID:16497345 -4.2.3.133 * helianthus annuus 64200.0 1 PMID:19580670 -4.2.3.133 * salvia sclarea 89758.0 1 PMID:22959531 -4.2.3.134 * mus musculus 51000.0 1 PMID:22241472 -4.2.3.134 * rattus norvegicus 140000.0 1 PMID:4412716 -4.2.3.135 * armillaria gallica 45000.0 1 PMID:21148562 -4.2.3.135 * omphalotus olearius 41070.0 2 PMID:23695581 -4.2.3.141 * salvia sclarea 61000.0 1 PMID:22834731 -4.2.3.142 * solanum habrochaites 84000.0 1 PMID:23169639 -4.2.3.143 * elaeoselinum garganicum 65000.0 2 PMID:22938155 -4.2.3.146 * streptomyces melanosporofaciens 78000.0 1 PMID:19635410 -4.2.3.148 * streptomyces sp. 95000.0 2 PMID:23386483 -4.2.3.149 * streptomyces sp. 95000.0 4 PMID:23386483 -4.2.3.15 * abies grandis 72500.0 1 PMID:9268308 -4.2.3.15 * alstroemeria caryophyllaea 65300.0 2 PMID:22268153 -4.2.3.15 * arabidopsis thaliana 69278.0 1 PMID:10700382 -4.2.3.15 * ochtodes secundiramea 69000.0 1 PMID:11913979 -4.2.3.150 * streptomyces sp. 69000.0 2 PMID:23386483 -4.2.3.151 * streptomyces sp. 69000.0 2 PMID:23386483 -4.2.3.152 * streptomyces albus 50550.0 2 PMID:18648803 -4.2.3.153 * methanocaldococcus jannaschii 171000.0 3 PMID:25372812;PMID:25905665 -4.2.3.155 * actinosynnema mirum 41009.0 1 PMID:22741921 -4.2.3.155 * stigmatella aurantiaca 43439.0 1 PMID:22741921 -4.2.3.16 * abies grandis 73500.0 1 PMID:9268308 -4.2.3.16 * agastache rugosa 70000.0 1 PMID:11305598 -4.2.3.16 * mentha sp. 59800.0 3 PMID:10398724;PMID:1559995;PMID:8226816;PMID:8442666 -4.2.3.16 * ricciocarpos natans 51000.0 1 PMID:8806745 -4.2.3.164 * sorangium cellulosum 40000.0 1 PMID:25504914 -4.2.3.17 * taxus brevifolia 98300.0 1 PMID:8621577 -4.2.3.17 * taxus canadensis 79000.0 1 PMID:9016812 -4.2.3.18 * abies grandis 90000.0 2 PMID:11112547;PMID:11552804 -4.2.3.18 * pinus densiflora 97900.0 1 PMID:19203978 -4.2.3.19 * cucurbita maxima 131000.0 6 PMID:12228665;PMID:8771778 -4.2.3.19 * fusarium fujikuroi 107000.0 1 PMID:10803977 -4.2.3.19 * fusarium verticillioides 490000.0 3 PMID:4331199 -4.2.3.19 * helianthus annuus 88015.0 2 PMID:20924785 -4.2.3.19 * marah macrocarpa 83000.0 3 PMID:16659781;PMID:16662063 -4.2.3.19 * phaeosphaeria sp. 132000.0 1 PMID:9268298 -4.2.3.19 * physcomitrium patens 106000.0 1 PMID:17064690 -4.2.3.194 * persicaria hydropiper 70000.0 1 * -4.2.3.198 * liquidambar formosana 64488.0 1 PMID:29746128 -4.2.3.2 * rattus norvegicus 168000.0 1 PMID:5498429 -4.2.3.20 * agastache rugosa 60000.0 1 PMID:12033511 -4.2.3.20 * citrus sinensis 70000.0 1 PMID:28272875 -4.2.3.20 * citrus unshiu 70000.0 1 * -4.2.3.20 * lavandula angustifolia 70300.0 1 PMID:17662687 -4.2.3.20 * schizonepeta tenuifolia 64000.0 2 PMID:11305598 -4.2.3.22 * streptomyces avermitilis 83000.0 1 PMID:17080683 -4.2.3.22 * streptomyces coelicolor 40000.0 1 PMID:12556563 -4.2.3.22 * streptomyces peucetius 98000.0 1 PMID:18667848 -4.2.3.23 * cichorium intybus 56000.0 2 PMID:9701594 -4.2.3.23 * crepidiastrum sonchifolium 80000.0 2 * -4.2.3.23 * helianthus annuus 64400.0 2 PMID:19580670 -4.2.3.23 * ixeridium dentatum 67100.0 1 * -4.2.3.23 * lavandula pedunculata 45000.0 1 PMID:24943828 -4.2.3.23 * lavandula viridis 45000.0 1 PMID:24943828 -4.2.3.23 * solidago canadensis 64700.0 1 PMID:12127586 -4.2.3.23 * tanacetum parthenium 64500.0 1 PMID:21620424 -4.2.3.24 * artemisia annua 69300.0 8 PMID:10626375;PMID:11032404;PMID:11185551;PMID:11289612;PMID:15797234;PMID:16724836 -4.2.3.25 * actinidia arguta 65000.0 1 * -4.2.3.25 * actinidia polygama 65000.0 1 * -4.2.3.25 * cereus peruvianus 53000.0 1 * -4.2.3.25 * clarkia breweri 79000.0 2 PMID:7864636 -4.2.3.25 * fragaria x ananassa 59200.0 2 PMID:17209074 -4.2.3.25 * santalum album 66620.0 1 PMID:33383368 -4.2.3.26 * artemisia annua 67400.0 2 PMID:10562427 -4.2.3.26 * mentha aquatica var. citrata 70500.0 1 PMID:12176064 -4.2.3.26 * solanum lycopersicum 70800.0 1 PMID:17440821 -4.2.3.27 * metrosideros polymorpha 65000.0 1 PMID:29902970 -4.2.3.27 * populus nigra 68000.0 1 PMID:21468716 -4.2.3.27 * populus tremula x populus alba 78000.0 5 PMID:16052321 -4.2.3.27 * populus tremuloides 137000.0 3 PMID:7768893 -4.2.3.27 * pueraria montana var. lobata 65000.0 1 PMID:19833224 -4.2.3.27 * quercus petraea 100000.0 1 * -4.2.3.3 * bacillus subtilis 105000.0 1 PMID:29514981 -4.2.3.3 * clostridium acetobutylicum 60000.0 2 PMID:10388730 -4.2.3.3 * escherichia coli 67000.0 2 PMID:236480;PMID:4368914;PMID:4563643;PMID:9665712 -4.2.3.3 * proteus vulgaris 135000.0 2 PMID:1386 -4.2.3.3 * roseateles saccharophilus 67000.0 1 PMID:236480;PMID:4368914;PMID:4563643;PMID:9665712 -4.2.3.3 * saccharomyces cerevisiae 53000.0 2 PMID:3899111 -4.2.3.3 * thermus sp. 89000.0 4 PMID:23592737 -4.2.3.3 * thermus sp. gh5 89000.0 2 PMID:20419481 -4.2.3.31 * streptomyces sp. 35000.0 1 PMID:17148547 -4.2.3.32 * ginkgo biloba 100289.0 1 PMID:11488601 -4.2.3.36 * kitasatospora griseola 70000.0 2 PMID:12138123 -4.2.3.38 * abies grandis 93776.0 1 PMID:9618485 -4.2.3.39 * artemisia annua 63500.0 1 PMID:10486140 -4.2.3.4 * actinidia chinensis 81000.0 5 PMID:21387027;PMID:23916589 -4.2.3.4 * aspergillus nidulans 43000.0 1 PMID:8037684 -4.2.3.4 * bacillus subtilis 24000.0 1 PMID:97286 -4.2.3.4 * cyberlindnera fabianii 330000.0 2 PMID:6270920 -4.2.3.4 * cyberlindnera jadinii 330000.0 2 PMID:6270920 -4.2.3.4 * escherichia coli 57000.0 8 PMID:21387027;PMID:2824247;PMID:3009224;PMID:3037261;PMID:6386050 -4.2.3.4 * lathyrus oleraceus 66000.0 1 * -4.2.3.4 * lodderomyces elongisporus 330000.0 2 PMID:6270920 -4.2.3.4 * meyerozyma guilliermondii 330000.0 2 PMID:6270920 -4.2.3.4 * mycobacterium tuberculosis 38140.0 2 PMID:17586643 -4.2.3.4 * neurospora crassa 330000.0 4 PMID:139889;PMID:4261463;PMID:6270920 -4.2.3.4 * ogataea henricii 330000.0 2 PMID:6270920 -4.2.3.4 * providencia alcalifaciens 80000.0 1 PMID:32661075 -4.2.3.4 * pyrococcus furiosus 72000.0 3 PMID:21387027;PMID:21603259 -4.2.3.4 * rhodotorula mucilaginosa 330000.0 1 PMID:6270920 -4.2.3.4 * rhodotorula sphaerocarpa 330000.0 1 PMID:6270920 -4.2.3.4 * rhodotorula toruloides 330000.0 1 PMID:6270920 -4.2.3.4 * saccharomyces cerevisiae 330000.0 1 PMID:6270920 -4.2.3.4 * saccharomycopsis lipolytica 330000.0 1 * -4.2.3.4 * sorghum sp. 330000.0 1 * -4.2.3.4 * thermus thermophilus 78400.0 1 PMID:15508124 -4.2.3.4 * vigna mungo 67000.0 2 * -4.2.3.4 * wickerhamomyces anomalus 330000.0 2 PMID:6270920 -4.2.3.41 * antillogorgia elisabethae 47000.0 1 PMID:15019841 -4.2.3.43 * diaporthe amygdali 900000.0 3 PMID:26734760;PMID:36227241 -4.2.3.45 * diaporthe amygdali 113000.0 1 PMID:18391465 -4.2.3.46 * actinidia deliciosa 88100.0 1 PMID:19516075 -4.2.3.46 * malus domestica 68000.0 2 PMID:14740213 -4.2.3.47 * artemisia annua 68000.0 3 PMID:15896363;PMID:21847661 -4.2.3.47 * citrus junos 63800.0 2 PMID:11642326 -4.2.3.48 * actinidia chinensis 65400.0 1 PMID:22162874 -4.2.3.48 * zea mays 50000.0 1 PMID:10805454 -4.2.3.49 * zea mays 140000.0 4 PMID:12481088 -4.2.3.5 * bacillus subtilis 24000.0 1 PMID:97285;PMID:97286 -4.2.3.5 * candida albicans 40895.0 1 PMID:31382783 -4.2.3.5 * capnoides sempervirens 80100.0 3 PMID:2146922;PMID:9951731 -4.2.3.5 * escherichia coli 190000.0 5 PMID:2969724;PMID:9951731 -4.2.3.5 * euglena gracilis 138000.0 3 PMID:16668543;PMID:9951731 -4.2.3.5 * helicobacter pylori 198000.0 1 PMID:12595729 -4.2.3.5 * mycobacterium tuberculosis 41800.0 1 PMID:18445278 -4.2.3.5 * neurospora crassa 198000.0 6 PMID:2955201;PMID:2969724;PMID:4155270;PMID:9951731 -4.2.3.5 * plasmodium falciparum 60480.0 2 PMID:21801743;PMID:31381947 -4.2.3.5 * plasmodium vivax 59960.0 1 PMID:31381947 -4.2.3.5 * saccharomyces cerevisiae 40800.0 2 PMID:9951731 -4.2.3.5 * solanum lycopersicum 41902.0 4 PMID:9951731 -4.2.3.5 * staphylococcus aureus 186800.0 3 PMID:8885411;PMID:9951731 -4.2.3.5 * thermotoga maritima 200000.0 3 PMID:11279147 -4.2.3.52 * lavandula angustifolia 62300.0 1 PMID:21165645 -4.2.3.52 * pinus contorta 67000.0 1 PMID:8307957 -4.2.3.56 * abies grandis 67940.0 1 PMID:9442047 -4.2.3.57 * lavandula angustifolia 63600.0 1 PMID:24078339 -4.2.3.6 * fusarium graminearum 46000.0 1 PMID:28456298 -4.2.3.6 * fusarium sporotrichioides 89000.0 6 PMID:16668409;PMID:17678871;PMID:17996718;PMID:2777086;PMID:3800398 -4.2.3.66 * citrus x microcarpa 67000.0 1 * -4.2.3.69 * arabidopsis thaliana 64908.0 1 PMID:15918888 -4.2.3.7 * streptomyces exfoliatus 42500.0 2 PMID:8180213;PMID:8563643 -4.2.3.7 * streptomyces sp. 57000.0 1 PMID:6642060 -4.2.3.70 * pogostemon cablin 80000.0 3 PMID:16970904;PMID:2171435 -4.2.3.71 * zingiber officinale 63800.0 2 PMID:16839518 -4.2.3.72 * solidago canadensis 60000.0 2 PMID:10190971 -4.2.3.73 * citrus sinensis 64000.0 1 PMID:14617067 -4.2.3.73 * vitis vinifera 64400.0 2 PMID:15464152 -4.2.3.75 * populus trichocarpa x populus deltoides 65000.0 1 PMID:14756770 -4.2.3.75 * solidago canadensis 65163.0 1 PMID:15542052 -4.2.3.75 * vitis vinifera 64300.0 1 PMID:15464152 -4.2.3.76 * abies grandis 67600.0 1 PMID:9442047 -4.2.3.77 * actinidia deliciosa 65200.0 1 PMID:19516075 -4.2.3.77 * solidago canadensis 64802.0 1 PMID:15542052 -4.2.3.77 * zingiber officinale 63800.0 2 PMID:16839518 -4.2.3.8 * ricinus communis 68960.0 3 PMID:16660566;PMID:3985625;PMID:8078910;PMID:8954576 -4.2.3.81 * santalum album 66000.0 2 PMID:21454632 -4.2.3.81 * santalum austrocaledonicum 65268.0 1 PMID:21454632 -4.2.3.81 * santalum spicatum 65407.0 1 PMID:21454632 -4.2.3.82 * santalum album 66000.0 4 PMID:21454632;PMID:23860319 -4.2.3.82 * santalum austrocaledonicum 65268.0 1 PMID:21454632 -4.2.3.82 * santalum spicatum 65407.0 1 PMID:21454632 -4.2.3.83 * santalum album 66000.0 2 PMID:21454632 -4.2.3.83 * santalum austrocaledonicum 65268.0 1 PMID:21454632 -4.2.3.83 * santalum spicatum 65407.0 1 PMID:21454632 -4.2.3.86 * vitis vinifera 64400.0 1 PMID:15464152 -4.2.3.87 * pogostemon cablin 64000.0 2 PMID:16970904 -4.2.3.89 * streptomyces griseus 41000.0 1 PMID:21693706 -4.2.3.9 * aspergillus terreus 70000.0 3 PMID:10775423;PMID:17261032 -4.2.3.9 * penicillium roqueforti 48000.0 4 PMID:20095558;PMID:2544140;PMID:8440737 -4.2.99.18 * african swine fever virus 34000.0 1 PMID:16641276 -4.2.99.18 * arabidopsis thaliana 43000.0 1 PMID:11094978 -4.2.99.18 * archaeoglobus fulgidus 23124.0 4 PMID:11425515 -4.2.99.18 * bacillus subtilis 105000.0 4 PMID:101548;PMID:7142160 -4.2.99.18 * bos taurus 40000.0 4 PMID:16617147;PMID:16891;PMID:2441359;PMID:3537712;PMID:7142159 -4.2.99.18 * chlamydomonas reinhardtii 38000.0 1 PMID:6722164 -4.2.99.18 * cricetulus griseus 35500.0 1 PMID:20955519 -4.2.99.18 * daucus carota 38000.0 1 PMID:6286302 -4.2.99.18 * desulfotomaculum nigrificans 18500.0 1 * -4.2.99.18 * drosophila melanogaster 67000.0 3 PMID:2419327 -4.2.99.18 * escherichia coli 33100.0 7 PMID:16960376;PMID:19223326;PMID:2669955;PMID:6265906;PMID:6351916 -4.2.99.18 * geobacillus stearothermophilus 28000.0 2 PMID:621207 -4.2.99.18 * homo sapiens 60000.0 15 PMID:14521941;PMID:17126083;PMID:1719477;PMID:1722334;PMID:18576638;PMID:18976116;PMID:19401441;PMID:20332233;PMID:2441359;PMID:7142159;PMID:9045706;PMID:9187114;PMID:9480425;PMID:9705289;PMID:9743625 -4.2.99.18 * hordeum vulgare 20000.0 2 PMID:668691 -4.2.99.18 * lactiplantibacillus plantarum 31800.0 1 PMID:16960376 -4.2.99.18 * leishmania major 56000.0 1 PMID:17870086 -4.2.99.18 * micrococcus luteus 18000.0 1 * -4.2.99.18 * mus musculus 65000.0 5 PMID:18393760;PMID:20332233;PMID:2457585;PMID:6253941;PMID:6256166;PMID:9705289;PMID:9743625 -4.2.99.18 * neisseria meningitidis 33000.0 1 PMID:17318183 -4.2.99.18 * phaseolus coccineus 40000.0 1 PMID:16891;PMID:2441359 -4.2.99.18 * pyrobaculum aerophilum 29467.0 1 PMID:15604455 -4.2.99.18 * pyrococcus abyssi 36200.0 1 PMID:17766251 -4.2.99.18 * rattus norvegicus 125000.0 7 PMID:19401441;PMID:6254770;PMID:6825667;PMID:7511117 -4.2.99.18 * saccharomyces cerevisiae 70000.0 9 PMID:17506861;PMID:18658271;PMID:6389517;PMID:9558341 -4.2.99.18 * thermoplasma volcanium 31400.0 1 PMID:16960376 -4.2.99.18 * toxoplasma gondii 51000.0 1 PMID:21353648 -4.2.99.20 * escherichia coli 25400.0 1 PMID:18284213 -4.2.99.21 * escherichia coli 88500.0 2 * -4.2.99.21 * pseudomonas aeruginosa 34000.0 5 PMID:11937513;PMID:7500944 -4.2.99.21 * yersinia enterocolitica 100000.0 2 PMID:16030197 -4.2.99.22 * tulipa gesneriana 87000.0 6 PMID:19661715;PMID:22474185;PMID:23649245 -4.2.99.23 * tulipa gesneriana 99000.0 4 PMID:25997073 -4.2.99.24 * papaver somniferum 40000.0 1 PMID:29807982 -4.3.1.1 * bacillus sp. (in: firmicutes) 200000.0 5 PMID:10334861;PMID:10712618;PMID:12761198;PMID:22527030 -4.3.1.1 * bacterium cadaveris 180000.0 1 * -4.3.1.1 * cytophaga sp. 192000.0 2 PMID:10334861;PMID:12761198 -4.3.1.1 * escherichia coli 193000.0 8 PMID:10800598;PMID:10995;PMID:2987841;PMID:3003513;PMID:3541901;PMID:4584395;PMID:6438071;PMID:9230045 -4.3.1.1 * haemophilus influenzae 55000.0 2 PMID:9092705 -4.3.1.1 * hafnia alvei 198000.0 2 PMID:9092705 -4.3.1.1 * lacticaseibacillus paracasei 50000.0 1 * -4.3.1.1 * propionibacterium freudenreichii subsp. shermanii 190000.0 1 PMID:16347414 -4.3.1.1 * pseudomonas aeruginosa 51000.0 1 PMID:27988856 -4.3.1.1 * pseudomonas fluorescens 173000.0 5 PMID:10800598;PMID:10995;PMID:3003513;PMID:3096982;PMID:4584395;PMID:6438071 -4.3.1.1 * yersinia pestis 52540.0 1 PMID:18451035 -4.3.1.1 * yersinia pseudotuberculosis 52470.0 1 PMID:18451035 -4.3.1.10 * sus scrofa 54500.0 4 PMID:5113489 -4.3.1.12 * agrobacterium tumefaciens 42000.0 2 PMID:2644238 -4.3.1.12 * clostridium sporogenes 81000.0 3 PMID:4373469 -4.3.1.12 * trichomonas vaginalis 36130.0 1 PMID:18541479 -4.3.1.14 * anaerobic bacteria 17000.0 1 PMID:17166837 -4.3.1.14 * clostridium sp. 64000.0 1 PMID:4420467 -4.3.1.15 * escherichia coli 84000.0 3 PMID:12821154;PMID:22505717 -4.3.1.15 * pseudomonas sp. 80000.0 2 PMID:240767 -4.3.1.15 * salmonella enterica subsp. enterica serovar typhimurium 96000.0 7 PMID:11914133;PMID:12821154;PMID:18025549;PMID:29294403;PMID:3275662 -4.3.1.16 * pseudomonas sp. 59000.0 1 PMID:10481099 -4.3.1.16 * pseudomonas sp. n99 39100.0 1 PMID:28290777 -4.3.1.16 * pseudomonas sp. t62 36000.0 1 PMID:19193709 -4.3.1.17 * acetoanaerobium sticklandii 250000.0 3 PMID:9637015 -4.3.1.17 * anaerotignum propionicum 230000.0 6 PMID:8344301 -4.3.1.17 * campylobacter jejuni 123000.0 2 PMID:14688104 -4.3.1.17 * clostridium acidi-urici 72000.0 1 * -4.3.1.17 * corynebacterium glyciniphilum 130000.0 1 * -4.3.1.17 * entamoeba histolytica 45000.0 1 PMID:19931317 -4.3.1.17 * escherichia coli 107000.0 6 PMID:15155761;PMID:15498577 -4.3.1.17 * homo sapiens 60000.0 5 PMID:15618015;PMID:16580895;PMID:4750769 -4.3.1.17 * legionella pneumophila 98950.0 4 PMID:22891658 -4.3.1.17 * limosilactobacillus fermentum 150000.0 2 * -4.3.1.17 * mus musculus 78000.0 5 PMID:12515328;PMID:12560076;PMID:16185077 -4.3.1.17 * mycolicibacterium smegmatis 57000.0 2 PMID:21656815 -4.3.1.17 * ovis aries 30500.0 1 PMID:11906824 -4.3.1.17 * paracoccus seriniphilus 53000.0 3 * -4.3.1.17 * peptoniphilus asaccharolyticus 200000.0 10 PMID:2065681;PMID:8236444 -4.3.1.17 * rattus norvegicus 68000.0 13 PMID:10212273;PMID:11906824;PMID:15618015;PMID:16793941;PMID:4750769;PMID:4800518 -4.3.1.18 * escherichia coli 48790.0 5 PMID:10601247;PMID:16290167;PMID:5327100;PMID:9222324 -4.3.1.18 * gallus gallus 77000.0 3 PMID:17977854 -4.3.1.18 * klebsiella pneumoniae 46000.0 2 PMID:32169 -4.3.1.18 * saccharomyces cerevisiae 118000.0 3 PMID:17937657 -4.3.1.18 * salmonella enterica subsp. enterica serovar typhimurium 49000.0 1 PMID:30173889 -4.3.1.19 * anaerotignum propionicum 160000.0 2 PMID:8344301 -4.3.1.19 * arabidopsis thaliana 268000.0 5 PMID:11106492;PMID:12427039 -4.3.1.19 * bacillus subtilis 46600.0 1 PMID:24324624 -4.3.1.19 * candida maltosa 190000.0 2 * -4.3.1.19 * cereibacter sphaeroides 210000.0 1 PMID:4539055 -4.3.1.19 * chloroflexus aurantiacus 120000.0 3 * -4.3.1.19 * clostridium tetanomorphum 184000.0 1 PMID:187387 -4.3.1.19 * corynebacterium glutamicum 210000.0 4 PMID:1459955;PMID:24324624 -4.3.1.19 * entamoeba histolytica 45000.0 1 PMID:19931317 -4.3.1.19 * escherichia coli 214000.0 14 PMID:1096954;PMID:187387;PMID:2005118;PMID:237884;PMID:240428;PMID:24324624;PMID:321452;PMID:4573981;PMID:4582943;PMID:6751404 -4.3.1.19 * euglena gracilis 250000.0 1 * -4.3.1.19 * geobacillus stearothermophilus 200000.0 2 PMID:10288 -4.3.1.19 * morganella morganii 230000.0 5 * -4.3.1.19 * mycolicibacterium smegmatis 180000.0 1 PMID:30226377 -4.3.1.19 * pseudomonas putida 54900.0 1 PMID:24324624 -4.3.1.19 * rattus norvegicus 64000.0 1 PMID:12535609 -4.3.1.19 * salmonella enterica subsp. enterica serovar typhimurium 120000.0 5 PMID:16511321;PMID:17046821;PMID:6751404 -4.3.1.19 * serratia marcescens 120000.0 3 * -4.3.1.19 * solanum lycopersicum 370000.0 5 PMID:12231753;PMID:17416643 -4.3.1.19 * staphylococcus aureus 46900.0 2 PMID:24324624 -4.3.1.19 * streptomyces griseus 42600.0 1 PMID:24324624 -4.3.1.19 * thermus sp. 115000.0 1 PMID:4706189 -4.3.1.2 * carboxydothermus hydrogenoformans 49000.0 1 PMID:22005738 -4.3.1.2 * citrobacter amalonaticus 84000.0 4 PMID:11748244;PMID:11796115;PMID:7576557;PMID:9385136 -4.3.1.2 * citrobacter freundii 79000.0 3 PMID:7765982;PMID:9385136 -4.3.1.2 * citrobacter koseri 40000.0 1 PMID:7765982;PMID:9385136 -4.3.1.2 * clostridium tetanomorphum 100000.0 6 PMID:11320320;PMID:11748244;PMID:11796115;PMID:1420191 -4.3.1.2 * escherichia coli 45000.0 1 * -4.3.1.2 * fusobacterium varium 88000.0 2 PMID:11506174 -4.3.1.2 * morganella morganii 70000.0 3 PMID:7765982;PMID:9385136 -4.3.1.2 * raoultella planticola 45000.0 1 PMID:9385136 -4.3.1.22 * cereibacter sphaeroides 274000.0 5 PMID:17616348 -4.3.1.23 * rhodotorula glutinis 75000.0 1 PMID:27401923 -4.3.1.24 * allium sativum 77000.0 1 PMID:20863129 -4.3.1.24 * alternaria sp. 560000.0 2 * -4.3.1.24 * angelica gigas 67020.0 1 PMID:20701298 -4.3.1.24 * arabidopsis thaliana 79100.0 4 PMID:15276452 -4.3.1.24 * bambusa oldhamii 360000.0 21 PMID:1191266;PMID:18280067;PMID:20064614;PMID:20354908;PMID:21035152;PMID:9887524 -4.3.1.24 * brassica juncea 170000.0 2 PMID:9509410 -4.3.1.24 * brassica rapa subsp. oleifera 38000.0 1 * -4.3.1.24 * centaurea depressa 70000.0 1 PMID:19725811;PMID:27246528 -4.3.1.24 * cistanche deserticola 94000.0 1 PMID:21104014 -4.3.1.24 * coleus scutellarioides 83000.0 1 PMID:26389875 -4.3.1.24 * cucumis sativus 316000.0 1 * -4.3.1.24 * cutaneotrichosporon cutaneum 79000.0 1 PMID:24159382 -4.3.1.24 * dolichospermum flos-aquae 64000.0 1 PMID:31581382 -4.3.1.24 * dracaena cambodiana 16180.0 1 PMID:23108992 -4.3.1.24 * ephedra sinica 79000.0 1 PMID:19043198 -4.3.1.24 * fallopia multiflora 84130.0 3 * -4.3.1.24 * fragaria x ananassa 266000.0 3 PMID:21683875 -4.3.1.24 * ginkgo biloba 79100.0 1 * -4.3.1.24 * glycine max 330000.0 3 PMID:18343145;PMID:7197898 -4.3.1.24 * gossypium hirsutum 337500.0 3 PMID:8043606 -4.3.1.24 * ipomoea batatas 330000.0 2 PMID:18343145 -4.3.1.24 * jatropha curcas 77300.0 1 PMID:21706349 -4.3.1.24 * kitagawia praeruptora 80000.0 1 PMID:25947617;PMID:30448740 -4.3.1.24 * limnospira platensis 64000.0 1 PMID:31581382 -4.3.1.24 * medicago sativa 316000.0 3 PMID:16667296 -4.3.1.24 * musa sp. 70000.0 1 PMID:18275463 -4.3.1.24 * mycosarcoma maydis 320000.0 2 PMID:18280067;PMID:20064614;PMID:9887524 -4.3.1.24 * nicotiana tabacum 280000.0 7 PMID:19725811;PMID:27246528 -4.3.1.24 * nostoc punctiforme 64000.0 1 PMID:17240984 -4.3.1.24 * oryza sativa 320000.0 2 PMID:18280067;PMID:21035152;PMID:9887524 -4.3.1.24 * petroselinum crispum 330000.0 4 PMID:4699991;PMID:7925471 -4.3.1.24 * phaseolus vulgaris 83000.0 2 PMID:1930141 -4.3.1.24 * photorhabdus luminescens 58000.0 1 PMID:33411135 -4.3.1.24 * pinus banksiana 354000.0 3 PMID:16668649 -4.3.1.24 * pinus taeda 280000.0 2 PMID:16668639 -4.3.1.24 * rhizoctonia solani 340000.0 6 PMID:1191266;PMID:20064614;PMID:21035152 -4.3.1.24 * rhodiola sachalinensis 77450.0 1 PMID:18426479 -4.3.1.24 * rhodotorula glutinis 320000.0 4 PMID:18280067;PMID:20064614;PMID:21035152;PMID:23338700;PMID:9887524 -4.3.1.24 * rhodotorula paludigena 78400.0 1 * -4.3.1.24 * salvia miltiorrhiza 77105.0 1 PMID:18454352 -4.3.1.24 * sinapis alba 255000.0 3 PMID:486502 -4.3.1.24 * solanum lycopersicum 320000.0 3 PMID:18280067;PMID:18343145;PMID:20064614;PMID:21035152;PMID:9887524 -4.3.1.24 * solanum tuberosum 330000.0 2 PMID:4699991 -4.3.1.24 * sorghum bicolor 75600.0 1 PMID:29196539 -4.3.1.24 * spirulina 66000.0 1 PMID:35713742 -4.3.1.24 * sporobolomyces pararoseus 75000.0 1 * -4.3.1.24 * streptomyces maritimus 60000.0 1 PMID:15937191 -4.3.1.24 * streptomyces verticillatus 226000.0 1 * -4.3.1.24 * trichormus variabilis 64000.0 2 PMID:17240984;PMID:23999738 -4.3.1.24 * tripidium arundinaceum 77000.0 1 * -4.3.1.24 * triticum aestivum 320000.0 8 PMID:18280067;PMID:21035152;PMID:9887524 -4.3.1.24 * zea mays 306000.0 3 PMID:25947617;PMID:30448740;PMID:4699991 -4.3.1.25 * bambusa oldhamii 290000.0 2 PMID:21035152 -4.3.1.25 * cutaneotrichosporon cutaneum 294000.0 2 * -4.3.1.25 * helianthus annuus 250000.0 4 * -4.3.1.25 * phanerodontia chrysosporium 70000.0 1 * -4.3.1.25 * plenodomus lingam 330000.0 2 * -4.3.1.25 * rhodotorula glutinis 300000.0 2 * -4.3.1.25 * rhodotorula toruloides 165000.0 2 * -4.3.1.25 * sorghum bicolor 75600.0 1 PMID:29196539 -4.3.1.25 * sporobolomyces pararoseus 300000.0 2 PMID:4673815 -4.3.1.27 * delftia sp. ht23 41600.0 5 PMID:20843822 -4.3.1.28 * streptomyces pristinaespiralis 37100.0 1 PMID:17291665 -4.3.1.29 * salmonella enterica subsp. enterica serovar typhimurium 84000.0 1 PMID:29277660 -4.3.1.3 * achromobacter liquidum 200000.0 1 PMID:240693 -4.3.1.3 * bacillus subtilis 220000.0 2 PMID:2454913 -4.3.1.3 * cavia porcellus 220000.0 1 * -4.3.1.3 * chlamydomonas reinhardtii 152400.0 2 PMID:15051050 -4.3.1.3 * comamonas testosteroni 200000.0 2 * -4.3.1.3 * homo sapiens 243000.0 1 * -4.3.1.3 * pseudomonas aeruginosa 210000.0 1 * -4.3.1.3 * pseudomonas fluorescens 218000.0 2 * -4.3.1.3 * pseudomonas putida 220000.0 3 PMID:10195286;PMID:8251759 -4.3.1.3 * pseudomonas sp. 210000.0 2 * -4.3.1.3 * rattus norvegicus 226000.0 4 PMID:15144042;PMID:4207867;PMID:5116 -4.3.1.3 * streptomyces griseus 55000.0 2 PMID:1612436 -4.3.1.3 * toad 204000.0 1 * -4.3.1.30 * streptomyces venezuelae 54265.0 2 PMID:19746907 -4.3.1.32 * methanocaldococcus jannaschii 42000.0 1 PMID:14593448 -4.3.1.32 * mycolicibacterium smegmatis 88000.0 1 PMID:14593448 -4.3.1.4 * clostridium cylindrosporum 38000.0 1 PMID:6016330 -4.3.1.4 * gallus gallus 59100.0 1 PMID:9677386 -4.3.1.4 * homo sapiens 496000.0 3 PMID:14697341;PMID:18571811 -4.3.1.4 * mammalia 500000.0 1 PMID:17470791 -4.3.1.4 * sus scrofa 538000.0 3 PMID:241297;PMID:7901203 -4.3.1.6 * anaerotignum propionicum 75000.0 2 PMID:15670161 -4.3.1.7 * clostridium sp. 520000.0 4 PMID:761617 -4.3.1.7 * escherichia coli 560400.0 5 PMID:19194002;PMID:33657 -4.3.1.7 * salmonella enterica subsp. enterica serovar typhimurium 500000.0 17 PMID:1550360;PMID:18041840;PMID:18444665;PMID:18805934;PMID:18826329;PMID:19899795;PMID:23374068 -4.3.1.9 * pseudomonas fluorescens 90000.0 6 PMID:12686150 -4.3.2.1 * agaricus bisporus 52340.0 1 PMID:17512708 -4.3.2.1 * anas platyrhynchos 55000.0 1 PMID:7944404 -4.3.2.1 * bos taurus 202000.0 3 PMID:1815504;PMID:3593239;PMID:495948;PMID:5082138;PMID:7263708 -4.3.2.1 * canis lupus familiaris 51700.0 1 PMID:18078854 -4.3.2.1 * chlamydomonas reinhardtii 218000.0 5 PMID:1815504;PMID:3593239;PMID:495948;PMID:588268;PMID:7263708 -4.3.2.1 * gallus gallus 190000.0 2 PMID:1815504;PMID:3593239;PMID:495948;PMID:7263708 -4.3.2.1 * homo sapiens 200000.0 6 PMID:11092456;PMID:1815504;PMID:3463959;PMID:3593239;PMID:495948;PMID:6784763;PMID:7263708 -4.3.2.1 * mycobacterium tuberculosis 50900.0 2 PMID:24316845;PMID:29044950 -4.3.2.1 * nostoc sp. 215000.0 2 PMID:11683360 -4.3.2.1 * rattus norvegicus 50000.0 1 PMID:20484304 -4.3.2.1 * saccharomyces cerevisiae 51944.0 1 PMID:3463959 -4.3.2.1 * streptococcus mutans 220000.0 2 PMID:21636911 -4.3.2.10 * escherichia coli 47500.0 1 PMID:8494895 -4.3.2.10 * saccharomyces cerevisiae 61082.0 5 PMID:10733892 -4.3.2.2 * artemia sp. 200000.0 2 PMID:19724117;PMID:3689310;PMID:6630197 -4.3.2.2 * bacillus subtilis 200000.0 11 PMID:15182182;PMID:16839792;PMID:17322529;PMID:17600142;PMID:18469177;PMID:3036807;PMID:8366112 -4.3.2.2 * ctenopharyngodon idella 54552.0 1 PMID:20857210 -4.3.2.2 * escherichia coli 200000.0 1 PMID:19724117;PMID:3689310;PMID:6630197 -4.3.2.2 * homo sapiens 230000.0 15 PMID:15182182;PMID:15471876;PMID:16839792;PMID:16973378;PMID:19405474;PMID:21210713;PMID:22812634;PMID:8366112 -4.3.2.2 * leishmania donovani 300000.0 1 PMID:468834 -4.3.2.2 * mus musculus 52000.0 1 PMID:16839792 -4.3.2.2 * neurospora crassa 200000.0 1 PMID:151182 -4.3.2.2 * plasmodium falciparum 56235.0 3 PMID:19111634;PMID:9274883 -4.3.2.2 * pyrobaculum aerophilum 52000.0 1 PMID:16839792 -4.3.2.2 * rattus norvegicus 200000.0 2 PMID:19724117;PMID:3689310;PMID:6630197 -4.3.2.2 * staphylococcus aureus 49600.0 1 PMID:20693687 -4.3.2.2 * thermotoga maritima 52000.0 1 PMID:16839792 -4.3.2.3 * bos taurus 64000.0 1 * -4.3.2.3 * cicer arietinum 180000.0 2 PMID:11161040 -4.3.2.3 * phaseolus vulgaris 240000.0 2 PMID:16333637 -4.3.2.3 * platyrrhini 64000.0 1 * -4.3.2.3 * rattus norvegicus 64000.0 2 PMID:7492331 -4.3.2.3 * saccharomyces cerevisiae 21727.0 1 PMID:1776360 -4.3.2.3 * sardinops melanosticta 121000.0 2 PMID:3741398 -4.3.2.5 * bos taurus 50000.0 2 PMID:1902227;PMID:2207061 -4.3.2.5 * drosophila melanogaster 51300.0 4 PMID:15198673 -4.3.2.5 * rattus norvegicus 75000.0 4 PMID:12369828;PMID:1699535;PMID:1898062;PMID:2357219 -4.3.2.6 * niallia circulans 20093.0 2 PMID:17462573 -4.3.2.7 * homo sapiens 22000.0 1 PMID:27913623 -4.3.2.7 * mus musculus 21000.0 1 PMID:27913623 -4.3.2.8 * glycine max 27000.0 1 PMID:9601076 -4.3.2.8 * homo sapiens 18000.0 1 PMID:20110353 -4.3.2.9 * homo sapiens 25250.0 6 PMID:18515354;PMID:20110353;PMID:29601 -4.3.2.9 * musca domestica 30000.0 1 * -4.3.2.9 * ralstonia solanacearum 50000.0 1 PMID:26823466 -4.3.2.9 * rattus norvegicus 27500.0 2 PMID:4735346 -4.3.3.1 * flavobacterium saccharophilum 40878.0 3 PMID:4093450 -4.3.3.1 * stenotrophomonas maltophilia 34000.0 1 PMID:19795222 -4.3.3.6 * bacillus subtilis 32830.0 1 PMID:21283685 -4.3.3.6 * geobacillus sp. h6a 420000.0 1 PMID:35350642 -4.3.3.6 * plasmodium falciparum 363000.0 2 PMID:20837012 -4.3.3.6 * pyrococcus horikoshii 200000.0 2 PMID:22505415 -4.3.3.7 * arabidopsis thaliana 34680.0 1 PMID:22102238 -4.3.3.7 * bacillus anthracis 124000.0 4 PMID:19595801;PMID:19948665 -4.3.3.7 * bacillus licheniformis 117000.0 2 PMID:1009127 -4.3.3.7 * bacillus subtilis 124000.0 1 PMID:4215809 -4.3.3.7 * caldanaerobacter subterraneus subsp. tengcongensis 150000.0 2 PMID:18340401 -4.3.3.7 * clostridium botulinum 31650.0 2 PMID:19255476 -4.3.3.7 * corynebacterium glutamicum 158000.0 2 PMID:18930704 -4.3.3.7 * escherichia coli 140000.0 7 PMID:14580236;PMID:16185069;PMID:18937497;PMID:35775984;PMID:4910051 -4.3.3.7 * lathyrus oleraceus 127000.0 2 PMID:16668753 -4.3.3.7 * mycobacterium tuberculosis 120000.0 2 PMID:17077492;PMID:21672512 -4.3.3.7 * neisseria meningitidis 31510.0 1 PMID:19236959 -4.3.3.7 * sinorhizobium meliloti 33000.0 1 PMID:16511261 -4.3.3.7 * spinacia oleracea 115000.0 1 * -4.3.3.7 * streptococcus pneumoniae 33780.0 1 PMID:20057065 -4.3.3.7 * thermotoga maritima 133000.0 4 PMID:16872276;PMID:21803176 -4.3.3.7 * trichormus variabilis 147000.0 1 PMID:27845445 -4.3.3.7 * triticum aestivum 123000.0 1 PMID:16665646 -4.3.3.7 * vibrio cholerae 68000.0 2 PMID:29337198 -4.3.3.7 * zea mays 130000.0 2 PMID:16668206 -4.3.3.7 * zizania latifolia 36000.0 1 * -4.3.3.8 * leucaena leucocephala 140000.0 2 PMID:24351687 -4.3.99.3 * bacillus subtilis 29000.0 1 PMID:23194065 -4.3.99.4 * klebsiella pneumoniae 124000.0 1 PMID:26187464 -4.3.99.5 * streptomyces cremeus 228500.0 2 PMID:29505698 -4.4.1.1 * ambystoma tigrinum 40000.0 1 PMID:17853447 -4.4.1.1 * aspergillus carneus 204000.0 1 PMID:26316161 -4.4.1.1 * bacillus cereus 170000.0 1 PMID:30036991;PMID:33301683 -4.4.1.1 * homo sapiens 156000.0 7 PMID:18029544;PMID:18476726;PMID:19200371;PMID:19631409;PMID:21886822;PMID:24707893 -4.4.1.1 * lactococcus lactis 41000.0 1 PMID:10620674 -4.4.1.1 * limosilactobacillus fermentum 140000.0 2 PMID:9770274 -4.4.1.1 * limosilactobacillus reuteri 160000.0 2 PMID:12222803 -4.4.1.1 * mus musculus 160000.0 6 PMID:15038791;PMID:17853447;PMID:19647029;PMID:20063035;PMID:629532 -4.4.1.1 * oenococcus oeni 41500.0 2 PMID:20922375 -4.4.1.1 * oryctolagus cuniculus 44500.0 1 PMID:19453900 -4.4.1.1 * rattus norvegicus 160000.0 7 PMID:18974309;PMID:19166813;PMID:19200371;PMID:19647029;PMID:5057891;PMID:6364702 -4.4.1.1 * staphylococcus aureus 160000.0 1 PMID:12222803 -4.4.1.1 * streptococcus anginosus 44000.0 1 PMID:12480520;PMID:12480900 -4.4.1.1 * streptococcus gordonii 44000.0 1 PMID:12480520;PMID:12480900 -4.4.1.1 * streptococcus mutans 44000.0 1 PMID:12480520;PMID:12480900 -4.4.1.1 * streptococcus oralis 44000.0 1 PMID:12480520;PMID:12480900 -4.4.1.1 * streptococcus salivarius 44000.0 1 PMID:12480520;PMID:12480900 -4.4.1.1 * streptococcus sobrinus 44000.0 1 PMID:12480520;PMID:12480900 -4.4.1.1 * streptomyces phaeochromogenes 168000.0 4 PMID:2821351;PMID:6432781 -4.4.1.1 * toxoplasma gondii 170000.0 1 PMID:30036991;PMID:33301683 -4.4.1.1 * xanthomonas oryzae pv. oryzae 42600.0 1 PMID:18678949 -4.4.1.10 * gallus gallus 120000.0 1 PMID:6364702 -4.4.1.11 * aeromonas sp. 159000.0 3 PMID:20146062 -4.4.1.11 * arabidopsis thaliana 48000.0 2 PMID:17030798 -4.4.1.11 * brevibacterium aurantiacum 170000.0 2 PMID:19251895;PMID:20146062;PMID:23083214;PMID:6742420;PMID:9726878 -4.4.1.11 * brevibacterium linens 170000.0 4 PMID:15574935;PMID:19089915;PMID:20146062;PMID:23083214;PMID:31711941;PMID:35691533;PMID:36675166;PMID:6742420;PMID:9056489;PMID:9726878 -4.4.1.11 * citrobacter freundii 200000.0 5 PMID:15901718;PMID:16511092;PMID:20146062;PMID:23083214;PMID:31711941;PMID:35691533;PMID:36675166;PMID:6742420;PMID:9726878 -4.4.1.11 * clostridium sporogenes 170000.0 3 PMID:20146062;PMID:24303205 -4.4.1.11 * clostridium tetani 258000.0 3 PMID:24303205 -4.4.1.11 * entamoeba histolytica 177000.0 6 PMID:12920135;PMID:17012806;PMID:20146062;PMID:23083214;PMID:6742420;PMID:9726878 -4.4.1.11 * fusobacterium nucleatum 170000.0 1 PMID:31711941;PMID:35691533;PMID:36675166;PMID:9726878 -4.4.1.11 * fusobacterium nucleatum subsp. nucleatum 154100.0 3 PMID:21798982 -4.4.1.11 * lactococcus lactis 55000.0 1 PMID:20146062 -4.4.1.11 * mus musculus 86700.0 6 PMID:16510603 -4.4.1.11 * porphyromonas gingivalis 170000.0 5 PMID:21798982;PMID:24303205 -4.4.1.11 * pseudomonas putida 180000.0 15 PMID:15574935;PMID:16012835;PMID:19089915;PMID:1953661;PMID:20146062;PMID:23083214;PMID:6742420;PMID:831771;PMID:8440;PMID:9056489;PMID:9473456;PMID:955094;PMID:9726878 -4.4.1.11 * pseudomonas sp. 150000.0 1 PMID:37305655 -4.4.1.11 * treponema denticola 167500.0 3 PMID:15845368;PMID:21798982 -4.4.1.11 * trichomonas vaginalis 160000.0 2 PMID:16012835;PMID:1953661;PMID:20146062;PMID:8440 -4.4.1.13 * arabidopsis thaliana 170000.0 2 PMID:8973544 -4.4.1.13 * bacillus sp. (in: firmicutes) 76000.0 2 PMID:1368609 -4.4.1.13 * bacillus subtilis 80000.0 1 PMID:8463265 -4.4.1.13 * bordetella avium 80000.0 3 PMID:8463265 -4.4.1.13 * brassica oleracea 100000.0 3 PMID:10794613;PMID:12525491;PMID:3782077 -4.4.1.13 * canis lupus familiaris 37000.0 1 PMID:21640784 -4.4.1.13 * echinochloa colona 43000.0 1 * -4.4.1.13 * escherichia coli 280000.0 1 PMID:7049234 -4.4.1.13 * felis sp. 37000.0 1 PMID:21640784 -4.4.1.13 * finegoldia magna 150000.0 1 PMID:8526486 -4.4.1.13 * fusobacterium varium 70000.0 1 PMID:6698982 -4.4.1.13 * homo sapiens 88000.0 2 PMID:25231977;PMID:3741406 -4.4.1.13 * lacticaseibacillus casei 47000.0 2 PMID:17993563 -4.4.1.13 * lactococcus lactis 165000.0 2 PMID:16535166 -4.4.1.13 * latilactobacillus sakei 281000.0 1 PMID:29563907 -4.4.1.13 * monieza expansa 72000.0 1 PMID:10779568 -4.4.1.13 * mus musculus 37000.0 1 PMID:21640784 -4.4.1.13 * oryctolagus cuniculus 37000.0 1 PMID:21640784 -4.4.1.13 * rattus norvegicus 330000.0 13 PMID:10794613;PMID:10900257;PMID:20306345;PMID:21640784;PMID:3782077;PMID:4008484;PMID:7814371;PMID:8286953;PMID:9049049 -4.4.1.13 * saccharomyces cerevisiae 195000.0 3 PMID:21478306 -4.4.1.13 * spinacia oleracea 210000.0 4 PMID:1898098;PMID:7840670 -4.4.1.13 * staphylococcus haemolyticus 170000.0 3 PMID:19035565 -4.4.1.13 * taraxacum brevicorniculatum 46127.0 1 * -4.4.1.13 * vachellia farnesiana 144000.0 2 PMID:241329 -4.4.1.14 * arabidopsis thaliana 55600.0 4 PMID:12422245;PMID:7642574 -4.4.1.14 * brassica oleracea 55000.0 1 PMID:12422245 -4.4.1.14 * citrus sinensis 54100.0 2 PMID:12422245 -4.4.1.14 * cucumis melo 56000.0 1 PMID:12422245 -4.4.1.14 * cucurbita maxima 160000.0 3 PMID:12422245;PMID:16665431 -4.4.1.14 * cucurbita pepo 100000.0 4 PMID:12422245;PMID:1995630;PMID:9535697 -4.4.1.14 * dendrobium hybrid cultivar 48500.0 1 * -4.4.1.14 * gossypium hirsutum 57900.0 2 PMID:21742672 -4.4.1.14 * lupinus albus 55000.0 2 PMID:12422245 -4.4.1.14 * malus domestica 52000.0 2 PMID:10610793;PMID:19587104 -4.4.1.14 * malus sylvestris 100000.0 3 PMID:16667960;PMID:2122449;PMID:7809054 -4.4.1.14 * musa acuminata 55000.0 1 PMID:14579075;PMID:20689184 -4.4.1.14 * oryza sativa 160000.0 2 PMID:12422245;PMID:16665431 -4.4.1.14 * pelargonium x hortorum 54100.0 1 PMID:12422245 -4.4.1.14 * penicillium citrinum 96000.0 2 PMID:11515533 -4.4.1.14 * picea glauca 58800.0 5 PMID:17122070 -4.4.1.14 * pseudotsuga menziesii 58900.0 1 PMID:17122070 -4.4.1.14 * rosa hybrid cultivar 55000.0 1 PMID:14579075;PMID:20689184 -4.4.1.14 * rubus idaeus 27300.0 1 * -4.4.1.14 * solanum lycopersicum 57000.0 4 PMID:16593770;PMID:16662947;PMID:16666248;PMID:2753036 -4.4.1.14 * solanum tuberosum 52900.0 2 PMID:12422245 -4.4.1.14 * vigna radiata 125000.0 3 PMID:12422245;PMID:3401016 -4.4.1.15 * arabidopsis thaliana 44000.0 5 PMID:15720402 -4.4.1.15 * escherichia coli 74000.0 6 PMID:11527960;PMID:3908101 -4.4.1.15 * methylorubrum extorquens 72000.0 1 PMID:29520528 -4.4.1.15 * solanum lycopersicum 51480.0 1 PMID:18825405 -4.4.1.15 * spinacia oleracea 67000.0 1 PMID:7110191 -4.4.1.16 * citrobacter freundii 64000.0 2 PMID:2991201 -4.4.1.16 * escherichia coli 88000.0 3 PMID:10329673 -4.4.1.16 * haloferax volcanii 110000.0 3 PMID:20226884 -4.4.1.16 * homo sapiens 93000.0 1 PMID:2821348;PMID:31480609;PMID:6461656 -4.4.1.16 * mus musculus 105000.0 4 PMID:10692412;PMID:11898407;PMID:2821348;PMID:31480609;PMID:6461656 -4.4.1.16 * sus scrofa 93000.0 3 PMID:2821348;PMID:31480609;PMID:6461656 -4.4.1.17 * homo sapiens 57000.0 1 PMID:23150584 -4.4.1.17 * saccharomyces cerevisiae 33000.0 2 PMID:16207709;PMID:3034577 -4.4.1.19 * methanocaldococcus jannaschii 86700.0 3 PMID:11830598 -4.4.1.2 * aspergillus fumigatus 50000.0 1 PMID:23568204 -4.4.1.20 * bos taurus 18000.0 1 PMID:12767051;PMID:1454853;PMID:15619010;PMID:9492288 -4.4.1.20 * homo sapiens 180000.0 7 PMID:12767051;PMID:12880868;PMID:12895593;PMID:1454853;PMID:15530365;PMID:15619010;PMID:8446623;PMID:9492288 -4.4.1.20 * mus musculus 18000.0 1 PMID:24810165 -4.4.1.20 * rattus norvegicus 18000.0 2 PMID:12767051;PMID:1454853;PMID:14637132;PMID:15619010;PMID:9492288 -4.4.1.21 * escherichia coli 12500.0 1 PMID:17014073 -4.4.1.22 * paracoccus denitrificans 21000.0 1 PMID:11741920 -4.4.1.23 * nocardioides sp. js614 40000.0 1 PMID:20121086 -4.4.1.24 * cupriavidus pinatubonensis 42000.0 1 PMID:20150239 -4.4.1.24 * paracoccus pantotrophus 42000.0 2 PMID:15758220 -4.4.1.25 * roseovarius nubinhibens 35000.0 1 PMID:19581363 -4.4.1.25 * ruegeria pomeroyi 100000.0 2 PMID:16302849 -4.4.1.26 * cannabis sativa 25000.0 2 * -4.4.1.28 * brassica napus 35000.0 2 PMID:23180220 -4.4.1.28 * fusobacterium nucleatum 37000.0 3 PMID:12393204 -4.4.1.28 * lactobacillus delbrueckii subsp. bulgaricus 170000.0 1 PMID:28003427 -4.4.1.28 * methanocaldococcus jannaschii 135000.0 2 PMID:15683250 -4.4.1.28 * prevotella intermedia 44000.0 1 PMID:19832801 -4.4.1.28 * treponema denticola 46000.0 1 PMID:10194060 -4.4.1.29 * prochlorococcus marinus subsp. pastoris 47100.0 2 PMID:20876568 -4.4.1.29 * thermosynechococcus vestitus 45600.0 2 PMID:24215428 -4.4.1.3 * alcaligenes sp. 48000.0 1 PMID:16534905 -4.4.1.3 * roseovarius nubinhibens 95300.0 3 PMID:20378650 -4.4.1.3 * ruegeria pomeroyi 36000.0 2 PMID:25993446 -4.4.1.3 * ulva curvata 78000.0 1 * -4.4.1.30 * limnospira platensis 22800.0 1 PMID:24768724 -4.4.1.32 * synechococcus elongatus 29000.0 2 PMID:8132596 -4.4.1.34 * rhodococcus sp. (in: high g+c gram-positive bacteria) 46000.0 2 PMID:9687433 -4.4.1.35 * brassica oleracea 47200.0 2 PMID:12525491 -4.4.1.35 * brassica oleracea var. italica 186000.0 8 PMID:10794613 -4.4.1.4 * allium ampeloprasum 580000.0 4 PMID:453844;PMID:9129337;PMID:9799098 -4.4.1.4 * allium cepa 200000.0 9 PMID:10759524;PMID:16665807;PMID:453844;PMID:9129337;PMID:9301115 -4.4.1.4 * allium fistulosum 220000.0 2 * -4.4.1.4 * allium sativum 111000.0 9 PMID:10193205;PMID:16665807;PMID:17174334;PMID:17262455;PMID:3740854;PMID:7979352 -4.4.1.4 * allium tuberosum 67000.0 3 PMID:9799098 -4.4.1.4 * cupriavidus necator 110000.0 1 PMID:30505192 -4.4.1.4 * ensifer adhaerens 96000.0 2 PMID:21906328 -4.4.1.4 * petiveria alliacea 218700.0 2 PMID:19789290 -4.4.1.42 * brassica sp. 22000.0 1 * -4.4.1.42 * enterobacteria phage t3 17000.0 1 PMID:110588 -4.4.1.45 * methanococcus maripaludis 60829.0 2 PMID:38100250 -4.4.1.45 * thermotoga maritima 61130.0 1 PMID:3570087 -4.4.1.5 * aeluropus lagopoides 33000.0 1 PMID:20397718 -4.4.1.5 * allium cepa 25000.0 2 PMID:19734676 -4.4.1.5 * aloe vera 44000.0 2 PMID:11513094;PMID:18533364;PMID:2076100 -4.4.1.5 * aspergillus niger 36000.0 1 PMID:3123469 -4.4.1.5 * bos taurus 44000.0 2 PMID:11513094;PMID:2076100 -4.4.1.5 * brassica juncea 56000.0 6 PMID:10205896;PMID:2037046;PMID:9887525 -4.4.1.5 * brassica oleracea 58000.0 1 * -4.4.1.5 * brassica sp. 58000.0 1 PMID:18533364 -4.4.1.5 * chlamydomonas reinhardtii 24000.0 1 * -4.4.1.5 * clostridium acetobutylicum 15818.0 1 PMID:21914803 -4.4.1.5 * cyberlindnera mrakii 38000.0 1 PMID:10666306 -4.4.1.5 * escherichia coli 34000.0 4 PMID:9628737 -4.4.1.5 * glycine max 60000.0 7 PMID:10666306;PMID:11171039;PMID:18533364;PMID:3109489;PMID:7763577;PMID:921763 -4.4.1.5 * homo sapiens 51000.0 9 PMID:20454582;PMID:24856185;PMID:443539;PMID:6173571;PMID:7154966;PMID:8449929;PMID:8489699 -4.4.1.5 * lactococcus lactis 43310.0 1 PMID:17993525 -4.4.1.5 * leishmania donovani 46000.0 3 PMID:16236261;PMID:19710909 -4.4.1.5 * leishmania infantum 18200.0 1 PMID:20445262 -4.4.1.5 * leishmania major 38700.0 3 PMID:15329410;PMID:19076214 -4.4.1.5 * macaca radiata 48000.0 2 PMID:10666306;PMID:11171039;PMID:3109489;PMID:921763 -4.4.1.5 * mus musculus 43000.0 5 PMID:1138914;PMID:18695250;PMID:7154967;PMID:880305 -4.4.1.5 * mytilus galloprovincialis 48000.0 3 PMID:3109489;PMID:921763 -4.4.1.5 * neisseria meningitidis 15670.0 2 PMID:15270717 -4.4.1.5 * onchocerca volvulus 45000.0 2 PMID:10666306;PMID:11171039;PMID:3109489;PMID:921763 -4.4.1.5 * oryctolagus cuniculus 42000.0 2 PMID:697868 -4.4.1.5 * oryza sativa japonica group 36000.0 3 PMID:11139585;PMID:24661284 -4.4.1.5 * ovis aries 45900.0 1 PMID:19241 -4.4.1.5 * plasmodium falciparum 43600.0 3 PMID:14623080;PMID:15843146 -4.4.1.5 * pseudomonas aeruginosa 14251.0 2 PMID:15270717 -4.4.1.5 * pseudomonas putida 21000.0 2 PMID:3101683 -4.4.1.5 * rattus norvegicus 54000.0 4 PMID:420861;PMID:6173571;PMID:7154966;PMID:953039 -4.4.1.5 * rhodospirillum rubrum 31000.0 1 * -4.4.1.5 * saccharomyces cerevisiae 33000.0 2 PMID:340274;PMID:393249 -4.4.1.5 * schizosaccharomyces pombe 34000.0 1 PMID:15042280 -4.4.1.5 * starmerella magnoliae 35500.0 1 PMID:21464599 -4.4.1.5 * sus scrofa 52000.0 3 PMID:10666306;PMID:11171039;PMID:3109489;PMID:4628223;PMID:921763 -4.4.1.5 * triticum aestivum 37000.0 3 PMID:10773335;PMID:18533364;PMID:19513813 -4.4.1.5 * trypanosoma cruzi 31300.0 5 PMID:16958620;PMID:19076214 -4.4.1.5 * yersinia pestis 148333.0 4 PMID:15270717 -4.4.1.9 * chromobacterium violaceum 70000.0 2 PMID:16233442 -4.4.1.9 * geobacillus stearothermophilus 70000.0 2 PMID:16233442 -4.4.1.9 * lathyrus latifolius 56000.0 2 * -4.4.1.9 * lupinus sp. 53000.0 1 PMID:1055433;PMID:5769995 -4.4.1.9 * malus domestica 40900.0 2 PMID:17333023 -4.4.1.9 * oryza sativa 40000.0 1 PMID:19181864 -4.4.1.9 * priestia megaterium 70000.0 2 PMID:20004515;PMID:5001194 -4.4.1.9 * solanum tuberosum 54000.0 4 PMID:10795315;PMID:11575729 -4.4.1.9 * spinacia oleracea 60000.0 3 PMID:10948226 -4.4.1.9 * vicia sativa subsp. nigra 54000.0 1 PMID:10795315 -4.4.1.9 * zonocerus variegatus 552300.0 2 PMID:17175447 -4.5.1.1 * musca domestica 120000.0 2 PMID:13673024;PMID:5136093 -4.5.1.1 * pseudomonas putida 37000.0 1 PMID:22239708 -4.5.1.2 * pseudomonas putida 76000.0 2 PMID:6427787;PMID:6815180 -4.5.1.3 * hyphomicrobium sp. 195000.0 3 PMID:3142855;PMID:3988708 -4.5.1.3 * methylophilus sp. 34000.0 1 PMID:3142855 -4.5.1.3 * methylorubrum extorquens 35000.0 1 PMID:3142855 -4.5.1.3 * niallia circulans 33000.0 2 PMID:17687552;PMID:19277720 -4.5.1.5 * escherichia coli 84000.0 3 * -4.6.1.1 * alternaria solani 500000.0 1 * -4.6.1.1 * amylomyces rouxii 510000.0 1 PMID:7181508 -4.6.1.1 * apis mellifera 147000.0 7 PMID:16464235;PMID:22426196 -4.6.1.1 * bordetella pertussis 215000.0 9 PMID:1693922;PMID:18992319;PMID:24907274;PMID:2867778;PMID:2877986;PMID:2896201;PMID:2897067;PMID:2901413 -4.6.1.1 * bos taurus 358000.0 5 PMID:13718;PMID:2034121;PMID:4041438;PMID:670196 -4.6.1.1 * catenaria anguillulae 21500.0 1 PMID:29799525 -4.6.1.1 * cavia porcellus 140000.0 2 PMID:17540702 -4.6.1.1 * escherichia coli 110000.0 2 PMID:4616139;PMID:6300054 -4.6.1.1 * euglena gracilis 400000.0 3 PMID:16786220 -4.6.1.1 * glutamicibacter nicotianae 110000.0 2 PMID:4616139;PMID:4817972 -4.6.1.1 * homo sapiens 192000.0 5 PMID:16570209;PMID:17591988 -4.6.1.1 * mammalia 187000.0 2 PMID:18948702 -4.6.1.1 * marchantia polymorpha 46000.0 1 PMID:34779957 -4.6.1.1 * medicago sativa 65000.0 1 PMID:3128270 -4.6.1.1 * mus musculus 192000.0 19 PMID:11423534;PMID:16570209;PMID:17088449;PMID:17190869;PMID:17335981;PMID:18948702;PMID:19307450 -4.6.1.1 * mycobacterium tuberculosis 45000.0 3 PMID:11431477;PMID:16403515;PMID:17482646 -4.6.1.1 * neurospora crassa 202000.0 1 PMID:6217814 -4.6.1.1 * oryctolagus cuniculus 150000.0 1 PMID:2034122 -4.6.1.1 * paramecium tetraurelia 98000.0 1 PMID:14607282 -4.6.1.1 * plasmodium falciparum 108000.0 3 PMID:12668669;PMID:14607282 -4.6.1.1 * pseudomonas aeruginosa 41670.0 2 PMID:22226839;PMID:9811898 -4.6.1.1 * rattus norvegicus 191000.0 15 PMID:11423534;PMID:16570209;PMID:16786220;PMID:17188522;PMID:17959750;PMID:18806876;PMID:19061075;PMID:670231;PMID:7225326;PMID:9874775 -4.6.1.1 * solanum tuberosum 225000.0 1 PMID:19061075 -4.6.1.1 * spodoptera frugiperda 25000.0 1 PMID:8702736 -4.6.1.1 * strongylocentrotus purpuratus 190000.0 2 PMID:17524362 -4.6.1.1 * synechocystis sp. pcc 6803 40000.0 1 PMID:15527795 -4.6.1.1 * yersinia pestis 40000.0 2 PMID:16511301 -4.6.1.12 * arabidopsis thaliana 18260.0 1 PMID:20480490 -4.6.1.12 * cephalotaxus harringtonia 26670.0 1 PMID:18923920 -4.6.1.12 * escherichia coli 17000.0 1 PMID:10694574 -4.6.1.12 * ginkgo biloba 26030.0 2 * -4.6.1.12 * mycobacterium tuberculosis 17000.0 1 PMID:20480490 -4.6.1.12 * plasmodium falciparum 21348.0 1 PMID:11389720 -4.6.1.12 * rauvolfia verticillata 25400.0 1 * -4.6.1.12 * shewanella oneidensis 17300.0 1 PMID:15502301 -4.6.1.12 * stevia rebaudiana 24800.0 1 PMID:23065206 -4.6.1.12 * taxus x media 26100.0 2 * -4.6.1.13 * bacillus cereus 35000.0 2 PMID:10986;PMID:12719256;PMID:207692 -4.6.1.13 * bacillus thuringiensis 34800.0 2 PMID:23506313;PMID:7417468 -4.6.1.13 * listeria monocytogenes 33000.0 4 PMID:12488013;PMID:19281241 -4.6.1.13 * streptomyces antibioticus 23000.0 2 PMID:7918603 -4.6.1.14 * trypanosoma brucei 47000.0 4 PMID:10764777;PMID:3759991;PMID:3782089 -4.6.1.15 * homo sapiens 59400.0 1 PMID:16289032 -4.6.1.15 * rattus norvegicus 140000.0 3 PMID:11695920 -4.6.1.16 * haloferax volcanii 37000.0 1 PMID:9200602;PMID:9582290 -4.6.1.16 * homo sapiens 45000.0 1 PMID:17495927;PMID:17786051 -4.6.1.16 * saccharolobus solfataricus 21700.0 1 PMID:17174977 -4.6.1.16 * saccharomyces cerevisiae 146000.0 8 PMID:2166218;PMID:9200603;PMID:9582290 -4.6.1.17 * mycobacterium tuberculosis 17500.0 2 PMID:22684071;PMID:23526978 -4.6.1.18 * bos taurus 27200.0 8 PMID:11193413;PMID:16233067;PMID:4573392;PMID:4710591;PMID:902865 -4.6.1.18 * ceratitis capitata 25000.0 1 PMID:3569265 -4.6.1.18 * gallus gallus 15767.0 2 PMID:16803891 -4.6.1.18 * homo sapiens 36000.0 6 PMID:12210760;PMID:12626415;PMID:3182786;PMID:6784751;PMID:7417455 -4.6.1.18 * rattus norvegicus 38300.0 5 PMID:17005942;PMID:4710591 -4.6.1.18 * saccharolobus solfataricus 8582.0 1 PMID:7875327 -4.6.1.18 * sus scrofa 13790.0 1 PMID:2410028 -4.6.1.19 * aquarana catesbeiana 25000.0 2 PMID:7742787;PMID:9178923 -4.6.1.19 * aspergillus niger 45000.0 1 * -4.6.1.19 * aspergillus oryzae 80000.0 4 PMID:3169020;PMID:6271742 -4.6.1.19 * aspergillus phoenicis 12500.0 2 PMID:239932;PMID:7096302 -4.6.1.19 * bacteroides sp. 53000.0 1 PMID:16644192 -4.6.1.19 * danio rerio 27300.0 4 PMID:19619322 -4.6.1.19 * escherichia coli 74000.0 1 PMID:16820694 -4.6.1.19 * homo sapiens 62100.0 3 PMID:23608948 -4.6.1.19 * hordeum vulgare 19000.0 1 PMID:6249375 -4.6.1.19 * irpex lacteus 45000.0 3 PMID:14586131;PMID:8541649 -4.6.1.19 * lentinula edodes 45000.0 1 PMID:14586131 -4.6.1.19 * magallana gigas 28000.0 2 PMID:8138535 -4.6.1.19 * momordica charantia 21190.0 1 PMID:15322360 -4.6.1.19 * oncorhynchus keta 25200.0 1 PMID:15725660 -4.6.1.19 * rattus norvegicus 30558.0 2 PMID:22216760 -4.6.1.19 * solanum lycopersicum 24000.0 1 PMID:10801354 -4.6.1.19 * trichoderma viride 27500.0 1 PMID:1794979 -4.6.1.19 * vigna unguiculata 16000.0 1 PMID:17899099 -4.6.1.19 * yarrowia lipolytica 32000.0 1 PMID:238621 -4.6.1.2 * aquarana catesbeiana 115000.0 2 PMID:1675787 -4.6.1.2 * arabidopsis thaliana 50300.0 1 PMID:21504901 -4.6.1.2 * arbacia punctulata 160000.0 2 PMID:6134728 -4.6.1.2 * asterias amurensis 500000.0 4 PMID:18461395 -4.6.1.2 * blastocladiella emersonii 21500.0 1 PMID:29799525 -4.6.1.2 * bos taurus 300000.0 15 PMID:16291256;PMID:1673683;PMID:1675787;PMID:1684292;PMID:18430586;PMID:18840097;PMID:4156069;PMID:6114859;PMID:9348080 -4.6.1.2 * callinectes sapidus 130000.0 3 PMID:18093588 -4.6.1.2 * catenaria anguillulae 21500.0 1 PMID:29799525 -4.6.1.2 * caulobacter vibrioides 160000.0 1 PMID:240841;PMID:31365;PMID:4155295 -4.6.1.2 * chlamydomonas reinhardtii 142000.0 3 PMID:30946781 -4.6.1.2 * drosophila melanogaster 143000.0 1 PMID:18044974 -4.6.1.2 * escherichia coli 30000.0 1 PMID:239941 -4.6.1.2 * homo sapiens 180000.0 13 PMID:10995472;PMID:15041475;PMID:19189860;PMID:20893;PMID:23269669;PMID:2576855;PMID:9742221 -4.6.1.2 * ipomoea nil 40000.0 1 PMID:18674925 -4.6.1.2 * leishmania donovani 106000.0 1 PMID:16507348 -4.6.1.2 * lymnaea stagnalis 111000.0 1 PMID:19909797 -4.6.1.2 * manduca sexta 150000.0 1 PMID:23934793 -4.6.1.2 * mus musculus 180000.0 4 PMID:16857755;PMID:21598940 -4.6.1.2 * rattus norvegicus 900000.0 22 PMID:16506200;PMID:16592607;PMID:1674571;PMID:17436468;PMID:17980861;PMID:20105301;PMID:20797390;PMID:234425;PMID:240841;PMID:31365;PMID:4155295 -4.6.1.2 * rhinella marina 115000.0 2 PMID:1675787 -4.6.1.20 * ustilago sphaerogena 22000.0 6 PMID:11582789;PMID:16110465;PMID:19297697;PMID:6271741 -4.6.1.21 * enterobacter sp. 31500.0 2 PMID:5142070 -4.6.1.22 * bacillus subtilis 300000.0 4 PMID:17129637;PMID:20025672;PMID:4989258 -4.6.1.23 * aspergillus giganteus 45000.0 4 PMID:18214983;PMID:22718791;PMID:7548154 -4.6.1.23 * cyclocybe aegerita 17000.0 2 PMID:28232091;PMID:30262416 -4.6.1.23 * pleurotus ostreatus 15000.0 1 PMID:32755707 -4.6.1.24 * aspergillus niger 13000.0 1 * -4.6.1.24 * aspergillus oryzae 11090.0 3 PMID:21179 -4.6.1.24 * bacillus amyloliquefaciens 53000.0 4 PMID:14985541;PMID:16213760;PMID:21824291 -4.6.1.24 * bacillus intermedius 12300.0 1 PMID:19968715 -4.6.1.24 * bacillus pumilus 12213.0 1 PMID:21824291 -4.6.1.24 * chalara sp. 12000.0 2 PMID:5079898;PMID:5079899 -4.6.1.24 * fusarium verticillioides 11000.0 1 PMID:6780547 -4.6.1.24 * mycobacterium tuberculosis 325000.0 2 PMID:17201693 -4.6.1.24 * synechocystis sp. pcc 6803 79000.0 1 PMID:17661085 -4.6.1.24 * ustilago sphaerogena 11000.0 1 PMID:5134542 -4.7.1.1 * escherichia coli 38000.0 2 PMID:21705661 -4.8.1.2 * pseudomonas chlororaphis 76400.0 5 PMID:12773527;PMID:29333684 -4.8.1.2 * pseudomonas sp. 85000.0 3 PMID:16003557 -4.8.1.2 * rhodococcus globerulus 76200.0 3 PMID:14556637 -4.8.1.2 * rhodococcus sp. n-771 80000.0 1 PMID:16233624 -4.8.1.3 * sclerotinia sclerotiorum 44000.0 2 PMID:21036375 -4.8.1.4 * bacillus sp. (in: firmicutes) 40000.0 1 PMID:10651646 -4.8.1.4 * bacillus sp. oxb-1 41902.0 1 PMID:34253740 -4.8.1.4 * bradyrhizobium sp. ltspm299 40700.0 1 PMID:29698761 -4.8.1.4 * fusarium graminearum 34100.0 1 PMID:16306715 -4.8.1.5 * arabidopsis thaliana 53000.0 1 PMID:28479247 -4.98.1.1 * bacillus subtilis 35000.0 1 PMID:8056770;PMID:8119288 -4.98.1.1 * bos taurus 200000.0 3 PMID:2310748;PMID:6487270;PMID:6688622;PMID:7173190;PMID:7309736 -4.98.1.1 * cereibacter sphaeroides 115000.0 2 PMID:3702737;PMID:6983526 -4.98.1.1 * chironomidae 86000.0 2 PMID:11451377 -4.98.1.1 * chironomus sp. 43000.0 2 PMID:15532727 -4.98.1.1 * chlamydomonas reinhardtii 54430.0 3 PMID:16306143;PMID:23700350 -4.98.1.1 * cucumis sativus 40000.0 1 PMID:10795314;PMID:19965627 -4.98.1.1 * cyanidioschyzon merolae 47000.0 1 PMID:16306143;PMID:23700350 -4.98.1.1 * drosophila melanogaster 42000.0 1 PMID:2310748;PMID:6487270;PMID:7309736 -4.98.1.1 * escherichia coli 35000.0 1 PMID:8056770;PMID:8119288 -4.98.1.1 * gallus gallus 320000.0 2 PMID:1033934;PMID:2310748;PMID:6487270;PMID:7309736 -4.98.1.1 * homo sapiens 84000.0 7 PMID:10795314;PMID:11215517;PMID:15574461;PMID:19965627;PMID:22897320;PMID:30765471;PMID:8031831 -4.98.1.1 * mus musculus 42000.0 3 PMID:10795314;PMID:14981080;PMID:18044970;PMID:19965627 -4.98.1.1 * novispirillum itersonii 50000.0 1 PMID:21163 -4.98.1.1 * plasmodium falciparum 42000.0 3 PMID:15307818 -4.98.1.1 * pseudomonas fluorescens 38000.0 1 PMID:11728716 -4.98.1.1 * rattus norvegicus 240000.0 3 PMID:2310748;PMID:6487270;PMID:7309736;PMID:7426014 -4.98.1.1 * saccharomyces cerevisiae 80000.0 3 PMID:11831847;PMID:22004247 -4.98.1.1 * sus scrofa 42000.0 1 PMID:20622448;PMID:22004247 -4.98.1.1 * synechocystis sp. pcc 6803 160000.0 3 PMID:18192382 -4.98.1.1 * thermus thermophilus 33000.0 1 PMID:22004247 -4.98.1.1 * vibrio vulnificus 512000.0 2 PMID:30251658 -4.99.1.10 * chenopodium album 20000.0 1 PMID:16228560 -4.99.1.10 * fragaria x ananassa 2180.0 1 * -4.99.1.2 * escherichia coli 32000.0 3 PMID:16211434;PMID:3542021 -4.99.1.2 * pseudomonas sp. 19000.0 1 PMID:9382 -4.99.1.3 * bacillus spizizenii 29300.0 1 * -4.99.1.3 * brucella melitensis 137000.0 3 PMID:19545636 -4.99.1.3 * methanobacter thermoautotrophicum 40000.0 3 PMID:12686546 -4.99.1.3 * methanosarcina barkeri 40000.0 4 PMID:12686546;PMID:17584754 -4.99.1.3 * nitratidesulfovibrio vulgaris 31000.0 3 PMID:18457416 -4.99.1.3 * paracoccus pantotrophus 23000.0 1 PMID:24673795 -4.99.1.3 * priestia megaterium 35000.0 1 PMID:12917443 -4.99.1.3 * synechocystis sp. 38000.0 1 PMID:12917443 -4.99.1.4 * arabidopsis thaliana 36010.0 2 PMID:22414210 -4.99.1.4 * paracoccus pantotrophus 20000.0 1 PMID:24673795 -4.99.1.4 * priestia megaterium 33000.0 1 PMID:12408752 -4.99.1.8 * plasmodium falciparum 25000.0 2 PMID:23471987;PMID:24025682 -4.99.1.9 * bacillus subtilis 40500.0 5 PMID:1459957;PMID:8119288 -5.1.1.1 * acidiphilium organovorum 65000.0 2 * -5.1.1.1 * acinetobacter baumannii 42000.0 1 PMID:23989159 -5.1.1.1 * alkalihalophilus pseudofirmus 87000.0 5 PMID:19194012;PMID:19269582;PMID:29427660 -5.1.1.1 * aquifex pyrophilus 80000.0 1 PMID:15302885;PMID:16310730;PMID:20971724 -5.1.1.1 * bacillus anthracis 93000.0 5 PMID:18453697;PMID:19074397;PMID:19192393;PMID:19695097 -5.1.1.1 * bacillus cereus 43660.0 1 PMID:24346000 -5.1.1.1 * bacillus subtilis 43650.0 1 PMID:18399999 -5.1.1.1 * bipolaris zeicola 42700.0 1 PMID:10671527 -5.1.1.1 * caldanaerobacter subterraneus subsp. tengcongensis 76000.0 2 PMID:23703245;PMID:23722847 -5.1.1.1 * cellana grata 41400.0 2 * -5.1.1.1 * chlamydomonas reinhardtii 72000.0 1 PMID:17469227 -5.1.1.1 * clostridioides difficile 86600.0 2 PMID:25004969 -5.1.1.1 * corynebacterium glutamicum 78000.0 2 PMID:16707184;PMID:3015202 -5.1.1.1 * enterococcus faecalis 67000.0 3 PMID:18239416;PMID:3921052 -5.1.1.1 * escherichia coli 80000.0 5 PMID:15302885;PMID:16310730;PMID:20971724 -5.1.1.1 * geobacillus stearothermophilus 78000.0 4 PMID:16707184;PMID:17680683;PMID:2192620;PMID:2835089;PMID:3015202 -5.1.1.1 * helicobacter pylori 68000.0 2 PMID:17196222 -5.1.1.1 * penaeus japonicus 45770.0 1 PMID:16141518 -5.1.1.1 * penaeus monodon 90000.0 4 PMID:12431412 -5.1.1.1 * peribacillus psychrosaccharolyticus 73000.0 2 PMID:10080917 -5.1.1.1 * procambarus clarkii 60000.0 2 PMID:11026672 -5.1.1.1 * pseudomonas aeruginosa 80000.0 4 PMID:15302885;PMID:16310730;PMID:20971724 -5.1.1.1 * pseudomonas fluorescens 80000.0 12 PMID:15302885;PMID:16310730;PMID:20971724;PMID:7763424 -5.1.1.1 * pseudomonas putida 80000.0 7 PMID:11676496;PMID:15302885;PMID:16310730;PMID:20971724;PMID:22806802 -5.1.1.1 * pyrococcus horikoshii 300000.0 2 PMID:30038603 -5.1.1.1 * salmonella enterica subsp. enterica serovar typhimurium 80000.0 8 PMID:15302885;PMID:16310730;PMID:20971724;PMID:3524677;PMID:6391537 -5.1.1.1 * schizosaccharomyces pombe 44000.0 1 PMID:11244061 -5.1.1.1 * shigella boydii 46000.0 2 PMID:11676496;PMID:22806802 -5.1.1.1 * shigella dysenteriae 46000.0 2 PMID:11676496;PMID:22806802 -5.1.1.1 * shigella flexneri 46000.0 2 PMID:11676496;PMID:22806802 -5.1.1.1 * shigella sonnei 46000.0 2 PMID:11676496;PMID:22806802 -5.1.1.1 * staphylococcus aureus 73000.0 2 PMID:22194336 -5.1.1.1 * streptococcus iniae 39820.0 1 PMID:31880879 -5.1.1.1 * streptococcus pneumoniae 39850.0 1 PMID:17509154 -5.1.1.1 * streptomyces coelicolor 83000.0 1 PMID:28042035 -5.1.1.1 * streptomyces lavendulae 80000.0 3 PMID:15302885;PMID:16310730;PMID:20971724 -5.1.1.1 * tolypocladium inflatum 150000.0 2 PMID:8175682 -5.1.1.10 * aeromonas caviae 80000.0 4 PMID:1920082;PMID:6427786 -5.1.1.10 * aplysia californica 57000.0 3 PMID:21343289 -5.1.1.10 * geobacillus kaustophilus 177300.0 5 PMID:19517534 -5.1.1.10 * latilactobacillus sakei 281000.0 1 PMID:29563907 -5.1.1.10 * mus musculus 78000.0 5 PMID:12515328;PMID:12560076;PMID:16185077 -5.1.1.10 * pseudomonas putida 110000.0 8 PMID:17028872;PMID:5788493;PMID:6439237;PMID:8320235 -5.1.1.10 * pseudomonas taetrolens 84000.0 2 PMID:19300994 -5.1.1.10 * pyrococcus horikoshii 91000.0 3 PMID:25963389;PMID:28343923 -5.1.1.11 * brevibacillus brevis 132000.0 7 PMID:20121951;PMID:2610939;PMID:5354026 -5.1.1.12 * acetoanaerobium sticklandii 92000.0 4 PMID:10715017;PMID:19251850 -5.1.1.13 * anadara broughtonii 63000.0 3 PMID:12568809;PMID:16452311 -5.1.1.13 * bifidobacterium bifidum 30000.0 2 PMID:15606767 -5.1.1.13 * mus musculus 45500.0 1 PMID:21757409 -5.1.1.13 * rattus norvegicus 45500.0 1 PMID:21757409 -5.1.1.13 * streptococcus thermophilus 60000.0 4 PMID:1907199;PMID:2054383 -5.1.1.13 * thermococcus litoralis 56000.0 1 PMID:27438592 -5.1.1.15 * achromobacter obae 51000.0 2 PMID:7160482 -5.1.1.15 * ensifer sp. 23-3 49800.0 1 PMID:28929416 -5.1.1.16 * agelenopsis aperta 29418.0 1 PMID:7622482 -5.1.1.17 * actinomyces sp. 50000.0 1 PMID:19374992 -5.1.1.17 * amycolatopsis lactamdurans 59000.0 1 * -5.1.1.17 * streptomyces clavuligerus 60000.0 3 PMID:2804141;PMID:6671166 -5.1.1.18 * arabidopsis thaliana 60000.0 2 PMID:16483618 -5.1.1.18 * dictyostelium discoideum 74400.0 2 PMID:22311068 -5.1.1.18 * homo sapiens 87500.0 2 PMID:22151352 -5.1.1.18 * hordeum vulgare 36000.0 2 PMID:17499824 -5.1.1.18 * mus musculus 153000.0 13 PMID:10557334;PMID:12021263;PMID:12515328;PMID:12560076;PMID:16185077;PMID:17094966;PMID:17976164;PMID:20890627;PMID:9892700 -5.1.1.18 * oryza sativa 87000.0 3 PMID:19249065;PMID:20564571 -5.1.1.18 * pyrobaculum islandicum 143000.0 5 PMID:17965169 -5.1.1.18 * pyrococcus horikoshii 300000.0 2 PMID:30038603 -5.1.1.18 * rattus norvegicus 38000.0 3 PMID:17094966;PMID:17976164;PMID:20091774;PMID:20890627;PMID:9892700 -5.1.1.18 * streptomyces garyphalus 93000.0 2 * -5.1.1.18 * zea mays 82000.0 1 PMID:26919519 -5.1.1.19 * streptomyces lavendulae subsp. lavendulae 31205.0 1 PMID:22307920 -5.1.1.20 * bacillus subtilis 39500.0 2 PMID:11747447 -5.1.1.20 * escherichia coli 34994.0 2 PMID:11747447 -5.1.1.21 * lentilactobacillus buchneri 200000.0 3 PMID:24039265;PMID:28344038 -5.1.1.3 * bacillus anthracis 32530.0 2 PMID:17496086 -5.1.1.3 * bacillus subtilis 37000.0 6 PMID:15502318;PMID:19772853;PMID:8385993;PMID:9604005 -5.1.1.3 * burkholderia cenocepacia 70000.0 2 PMID:27898711 -5.1.1.3 * escherichia coli 31000.0 1 PMID:7901215 -5.1.1.3 * fusobacterium nucleatum subsp. nucleatum 35000.0 2 PMID:19772853 -5.1.1.3 * fusobacterium varium 29000.0 2 PMID:21575137 -5.1.1.3 * lactiplantibacillus plantarum 55800.0 2 PMID:23228473 -5.1.1.3 * levilactobacillus brevis 29430.0 2 PMID:7772825 -5.1.1.3 * limosilactobacillus fermentum 30000.0 2 PMID:5363991;PMID:8385993;PMID:9604005 -5.1.1.3 * mycobacterium tuberculosis 54200.0 2 PMID:17020913;PMID:26964898 -5.1.1.3 * mycolicibacterium smegmatis 59500.0 1 PMID:26964898 -5.1.1.3 * pediococcus pentosaceus 40000.0 3 PMID:1821778;PMID:7937852 -5.1.1.3 * streptococcus iniae 30000.0 1 PMID:32093601 -5.1.1.3 * streptococcus pyogenes 29000.0 1 PMID:17658548 -5.1.1.4 * acetoanaerobium sticklandii 38000.0 1 PMID:1174513 -5.1.1.4 * clostridioides difficile 80000.0 2 PMID:25786142 -5.1.1.4 * ferroplasma acidarmanus 80000.0 2 PMID:25786142 -5.1.1.4 * haloarcula japonica 80000.0 2 PMID:25786142 -5.1.1.4 * thermococcus litoralis 80000.0 2 PMID:25786142 -5.1.1.4 * trypanosoma cruzi 80000.0 5 PMID:10932226;PMID:12735293;PMID:19917711 -5.1.1.4 * trypanosoma vivax 40000.0 1 PMID:19428664 -5.1.1.5 * uncultured bacterium 43000.0 2 PMID:19502445;PMID:19834817 -5.1.1.6 * pseudomonas putida 82000.0 2 PMID:8320235 -5.1.1.7 * acinetobacter baumannii 31100.0 1 PMID:23295484 -5.1.1.7 * escherichia coli 61300.0 5 PMID:20057066;PMID:23426375;PMID:6378903;PMID:9559056 -5.1.1.7 * mycobacterium tuberculosis 30000.0 1 PMID:16907737 -5.1.1.8 * ferroplasma acidarmanus 80000.0 2 PMID:25786142 -5.1.1.8 * pseudomonas putida 64000.0 6 PMID:14189888;PMID:5469165;PMID:6706934 -5.1.1.8 * thermococcus litoralis 80000.0 2 PMID:25786142 -5.1.1.9 * pseudomonas graveolens 167000.0 1 PMID:5570439;PMID:5779761 -5.1.1.9 * pseudomonas taetrolens 42000.0 1 PMID:20564572 -5.1.2.1 * clostridium butyricum 82400.0 1 PMID:4810054 -5.1.2.1 * lacticaseibacillus casei 60000.0 1 PMID:4205608 -5.1.2.1 * latilactobacillus curvatus 60000.0 1 PMID:4205608 -5.1.2.1 * latilactobacillus sakei 60000.0 2 PMID:4205608;PMID:5707819 -5.1.2.1 * megasphaera elsdenii 50000.0 1 PMID:8439152 -5.1.2.2 * pseudomonas putida 278000.0 6 PMID:18092808;PMID:386722;PMID:4989844 -5.1.2.3 * cucumis sativus 79047.0 1 PMID:8051146 -5.1.2.3 * escherichia coli 78000.0 2 PMID:7012144;PMID:7024730 -5.1.2.3 * neurospora crassa 365000.0 3 PMID:1830048;PMID:1830049 -5.1.2.3 * pseudomonas fragi 73000.0 2 PMID:2361950 -5.1.3.1 * bos taurus 43000.0 3 PMID:3987693;PMID:497230 -5.1.3.1 * homo sapiens 45000.0 2 PMID:6882362 -5.1.3.1 * oryza sativa 55000.0 2 PMID:10625676 -5.1.3.1 * saccharomyces cerevisiae 50000.0 5 PMID:6882362;PMID:8879247;PMID:9032985 -5.1.3.1 * spinacia oleracea 200000.0 4 PMID:9523694;PMID:9733539 -5.1.3.11 * [eubacterium] cellulosolvens 46963.0 2 PMID:18710396 -5.1.3.11 * bacteroides fragilis 45780.0 2 PMID:19202279 -5.1.3.11 * caldicellulosiruptor morganii 90000.0 2 PMID:34031874 -5.1.3.11 * caldicellulosiruptor obsidiansis 43000.0 1 PMID:27873314 -5.1.3.11 * caldicellulosiruptor saccharolyticus 47340.0 5 PMID:21691788;PMID:22123300;PMID:31733243;PMID:34231359 -5.1.3.11 * dictyoglomus turgidum 47200.0 2 PMID:22782272 -5.1.3.11 * ruminococcus albus 44000.0 3 PMID:17612504;PMID:18392616 -5.1.3.11 * thermoanaerobacterium saccharolyticum 47000.0 1 PMID:29290443 -5.1.3.11 * thermoanaerobacterium thermosaccharolyticum 46000.0 1 PMID:31401280 -5.1.3.11 * treponema brennaborense 47150.0 2 PMID:31733243;PMID:34231359 -5.1.3.11 * winmispira thermophila 47000.0 1 PMID:23801120 -5.1.3.13 * acanthamoeba polyphaga mimivirus 47000.0 2 PMID:20538863 -5.1.3.13 * escherichia coli 67000.0 1 PMID:109125 -5.1.3.13 * mycobacterium tuberculosis 22000.0 1 PMID:17046787 -5.1.3.13 * pseudomonas aeruginosa 22000.0 1 PMID:17046787 -5.1.3.13 * saccharothrix syringae 54200.0 2 PMID:34819927 -5.1.3.13 * salmonella enterica 40600.0 2 PMID:10455186;PMID:17046787 -5.1.3.13 * streptomyces niveus 40000.0 1 PMID:15752721 -5.1.3.14 * bordetella pertussis 40000.0 2 PMID:11526328 -5.1.3.14 * escherichia coli 76000.0 2 PMID:381306;PMID:7048002 -5.1.3.14 * methanococcus maripaludis 101000.0 3 PMID:18263721 -5.1.3.14 * rattus norvegicus 500000.0 6 PMID:10497249;PMID:15330759;PMID:17448495;PMID:9305887;PMID:9305888 -5.1.3.15 * escherichia coli 30000.0 1 PMID:4589555 -5.1.3.15 * rhodotorula toruloides 30000.0 1 PMID:4589555 -5.1.3.15 * saccharomyces cerevisiae 35000.0 1 PMID:11946648;PMID:236478 -5.1.3.15 * solanum tuberosum 45000.0 2 PMID:4589555 -5.1.3.17 * bermanella marisrubri 52000.0 2 PMID:23824188 -5.1.3.17 * bos taurus 52000.0 2 PMID:7929434;PMID:9346972 -5.1.3.17 * danio rerio 125000.0 1 PMID:25568314 -5.1.3.17 * mus musculus 56000.0 2 PMID:6768743 -5.1.3.18 * arabidopsis thaliana 84000.0 2 PMID:11752432 -5.1.3.18 * auxenochlorella pyrenoidosa 100000.0 1 PMID:443816;PMID:7098948 -5.1.3.18 * solanum lycopersicum 42550.0 2 PMID:20981454 -5.1.3.19 * bos taurus 89000.0 1 PMID:16505484 -5.1.3.2 * aeromonas hydrophila 38270.0 2 PMID:17553760 -5.1.3.2 * arabidopsis thaliana 103000.0 10 PMID:16644739;PMID:8615692 -5.1.3.2 * aspergillus nidulans 40600.0 2 PMID:20211750;PMID:24116166 -5.1.3.2 * avibacterium paragallinarum 37000.0 1 PMID:17541831 -5.1.3.2 * bacillus anthracis 37800.0 2 PMID:19749053 -5.1.3.2 * bifidobacterium bifidum 90000.0 2 * -5.1.3.2 * bos taurus 40000.0 3 PMID:845161 -5.1.3.2 * candida albicans 75480.0 1 PMID:17178245 -5.1.3.2 * corynebacterium glutamicum 35400.0 1 PMID:8921853 -5.1.3.2 * escherichia coli 320000.0 15 PMID:11437350;PMID:14235524;PMID:17105195;PMID:1821806;PMID:29159585;PMID:7873670;PMID:9119006;PMID:9224707 -5.1.3.2 * galdieria sulphuraria 83000.0 3 * -5.1.3.2 * homo sapiens 38266.0 1 PMID:8593531 -5.1.3.2 * hordeum vulgare 39000.0 2 PMID:16266295 -5.1.3.2 * kluyveromyces marxianus 240000.0 7 PMID:14686919;PMID:8373776;PMID:9826189 -5.1.3.2 * lathyrus oleraceus 56000.0 4 PMID:19754426 -5.1.3.2 * mycobacterium tuberculosis 67000.0 1 PMID:28403215 -5.1.3.2 * papaver somniferum 39317.0 1 * -5.1.3.2 * poterioochromonas malhamensis 120000.0 2 * -5.1.3.2 * pyrobaculum calidifontis 51000.0 2 PMID:21645492 -5.1.3.2 * pyrococcus horikoshii 70000.0 2 PMID:22342090;PMID:26344854 -5.1.3.2 * rickettsia prowazekii 38000.0 1 PMID:16386381 -5.1.3.2 * saccharomyces cerevisiae 187000.0 2 PMID:6292668;PMID:6987227 -5.1.3.2 * streptomyces thermophilus 37000.0 1 PMID:1694527 -5.1.3.2 * thermotoga maritima 70000.0 2 PMID:22342090;PMID:26344854 -5.1.3.2 * thermus thermophilus 35000.0 1 PMID:19800315 -5.1.3.2 * trigonella sp. 70000.0 1 PMID:22342090;PMID:26344854 -5.1.3.2 * vicia faba 78000.0 1 * -5.1.3.2 * xanthomonas campestris 42213.0 1 PMID:24120348 -5.1.3.20 * burkholderia thailandensis 38000.0 1 PMID:23519675 -5.1.3.20 * escherichia coli 250000.0 2 PMID:7929099 -5.1.3.20 * haemophilus influenzae 35000.0 1 PMID:9119477 -5.1.3.21 * levilactobacillus brevis 45000.0 2 PMID:7796915 -5.1.3.23 * bordetella pertussis 42600.0 1 PMID:17346239 -5.1.3.23 * pseudomonas aeruginosa 40300.0 1 PMID:17346239 -5.1.3.24 * escherichia coli 73900.0 2 PMID:18063573 -5.1.3.27 * streptomyces sp. 38000.0 1 PMID:17053005 -5.1.3.28 * pseudomonas aeruginosa 43900.0 1 PMID:12464616 -5.1.3.28 * staphylococcus aureus 43900.0 1 PMID:12464616 -5.1.3.3 * aspergillus niger 260000.0 2 PMID:7317442 -5.1.3.3 * bos taurus 41300.0 5 PMID:4709943;PMID:4711601 -5.1.3.3 * capsicum frutescens 50000.0 2 PMID:4711601;PMID:805343 -5.1.3.3 * cavia porcellus 38100.0 1 PMID:4711601 -5.1.3.3 * entamoeba histolytica 38000.0 1 PMID:15869755 -5.1.3.3 * escherichia coli 34000.0 1 PMID:20693678 -5.1.3.3 * gallus gallus 35900.0 1 PMID:4711601 -5.1.3.3 * homo sapiens 37500.0 2 PMID:12753898;PMID:4711601 -5.1.3.3 * oryctolagus cuniculus 37500.0 2 PMID:4711601 -5.1.3.3 * ovis aries 38100.0 2 PMID:4711601 -5.1.3.3 * penicillium chrysogenum 70000.0 1 PMID:13799037 -5.1.3.3 * perca flavescens 37400.0 1 PMID:4711601 -5.1.3.3 * rattus norvegicus 41800.0 3 PMID:6630166 -5.1.3.3 * salmonella enterica subsp. enterica serovar typhimurium 34000.0 2 PMID:17242513 -5.1.3.3 * sus scrofa 41000.0 5 PMID:7118851 -5.1.3.3 * trichoderma reesei 42380.0 3 PMID:18480250 -5.1.3.30 * desmospora sp. 8437 132000.0 2 PMID:22760176;PMID:24199681 -5.1.3.30 * escherichia coli 26000.0 1 PMID:32451803 -5.1.3.30 * ruminiclostridium cellulolyticum 130000.0 3 PMID:21663329;PMID:29838926 -5.1.3.30 * ruminococcus sp. 140000.0 4 PMID:22760176;PMID:24199681;PMID:31797048 -5.1.3.31 * caballeronia fortuita 70000.0 2 PMID:31330210;PMID:33363120;PMID:35871484 -5.1.3.31 * caballeronia insecticola 65000.0 2 PMID:31330210;PMID:33363120;PMID:35871484 -5.1.3.31 * cereibacter sphaeroides 64000.0 2 PMID:19205890 -5.1.3.31 * christensenella minuta 33000.0 1 PMID:31330210;PMID:33363120;PMID:35871484 -5.1.3.31 * methanocaldococcus jannaschii 60000.0 1 PMID:25005083 -5.1.3.31 * pseudomonas sp. 68000.0 2 PMID:35518988 -5.1.3.31 * sinorhizobium sp. 68000.0 1 PMID:35518988 -5.1.3.32 * rhizobium leguminosarum 28000.0 4 PMID:18156270 -5.1.3.33 * actinomyces sp. 48000.0 2 PMID:19101977 -5.1.3.35 * actinoplanes sp. 30616.0 2 PMID:12681481 -5.1.3.36 * lissachatina fulica 75000.0 1 PMID:25677302 -5.1.3.37 * azotobacter vinelandii 150000.0 10 PMID:10212201;PMID:15244442;PMID:35734252 -5.1.3.37 * pseudomonas aeruginosa 60000.0 2 PMID:8144447 -5.1.3.4 * escherichia coli 105000.0 4 PMID:4879898;PMID:9548961 -5.1.3.4 * klebsiella aerogenes 114000.0 1 PMID:4395381 -5.1.3.44 * dyadobacter fermentans 101000.0 1 PMID:31201453 -5.1.3.44 * runella slithyformis 81000.0 1 PMID:31201453 -5.1.3.45 * salmonella enterica subsp. enterica serovar typhi 73000.0 2 PMID:16800641 -5.1.3.5 * hordeum vulgare 47000.0 2 PMID:20435741 -5.1.3.5 * lathyrus oleraceus 56000.0 3 PMID:19754426 -5.1.3.5 * sinorhizobium meliloti 66000.0 2 PMID:20847005 -5.1.3.6 * arabidopsis thaliana 88500.0 6 PMID:15563616;PMID:19564155 -5.1.3.6 * dolichospermum flos-aquae 54000.0 1 PMID:4150793 -5.1.3.6 * oryza sativa 92200.0 2 PMID:19564155 -5.1.3.6 * streptococcus pneumoniae 80000.0 2 PMID:10027985 -5.1.3.6 * zea mays 81400.0 2 PMID:19564155 -5.1.3.7 * bacillus anthracis 37800.0 1 PMID:19749053 -5.1.3.7 * bacillus subtilis 62000.0 1 PMID:34224569 -5.1.3.7 * escherichia coli 39807.0 1 PMID:29159585 -5.1.3.7 * giardia duodenalis 42000.0 1 PMID:17403156 -5.1.3.7 * pseudomonas aeruginosa 80000.0 1 PMID:10747995 -5.1.3.7 * thermotoga maritima 70000.0 2 PMID:26344854 -5.1.3.7 * thermus thermophilus 35000.0 1 PMID:19800315 -5.1.3.8 * anabaena sp. ch1 42000.0 1 PMID:17349707 -5.1.3.8 * homo sapiens 85000.0 4 PMID:10502668;PMID:11098137;PMID:8663114;PMID:9990133 -5.1.3.8 * sus scrofa 93000.0 4 PMID:17023685;PMID:8663114;PMID:9990133 -5.1.3.8 * synechocystis sp. pcc 6803 40000.0 1 PMID:19888576 -5.1.99.1 * metallosphaera sedula 32100.0 4 PMID:22752162 -5.1.99.1 * propionibacterium freudenreichii subsp. shermanii 35000.0 3 PMID:7325964 -5.1.99.1 * pyrococcus horikoshii 31700.0 1 PMID:14586582 -5.1.99.1 * rattus norvegicus 32000.0 2 PMID:2862845;PMID:3071715 -5.1.99.2 * homo sapiens 48500.0 1 PMID:5657462 -5.1.99.3 * klebsiella oxytoca 25578.0 1 PMID:19060149 -5.1.99.3 * pseudomonas fluorescens 55000.0 1 PMID:27797489 -5.1.99.4 * homo sapiens 47700.0 10 PMID:14960364;PMID:15880524;PMID:19156321;PMID:7649182 -5.1.99.4 * mycobacterium sp. 39000.0 1 PMID:15489432 -5.1.99.4 * mycobacterium tuberculosis 89000.0 5 PMID:12554951;PMID:15632186;PMID:19854148 -5.1.99.4 * rattus norvegicus 44900.0 2 PMID:8020470 -5.1.99.5 * agrobacterium tumefaciens 100000.0 4 PMID:12467452;PMID:12659852;PMID:14711700;PMID:15016445;PMID:15784981 -5.1.99.5 * arthrobacter sp. 84000.0 2 * -5.1.99.5 * microbacterium maritypicum 117000.0 2 PMID:15016445;PMID:15784981 -5.1.99.5 * pseudomonas sp. 190000.0 2 PMID:1459947 -5.1.99.5 * sinorhizobium meliloti 100000.0 2 PMID:12659852;PMID:14711700;PMID:15016445 -5.1.99.7 * escherichia coli 82600.0 3 PMID:9182560 -5.1.99.7 * pseudomonas aeruginosa 141500.0 1 PMID:22575651 -5.1.99.8 * arabidopsis thaliana 16300.0 4 PMID:15107504 -5.1.99.8 * escherichia coli 111600.0 4 PMID:9006053;PMID:9651328 -5.1.99.8 * solanum lycopersicum 14600.0 1 PMID:15107504 -5.2.1.1 * alcaligenes faecalis 100000.0 4 PMID:9345272 -5.2.1.1 * pseudomonas fluorescens 74000.0 1 PMID:5780844 -5.2.1.1 * pseudomonas sp. 74000.0 1 PMID:5780844 -5.2.1.1 * serratia marcescens 28000.0 2 PMID:10945267 -5.2.1.13 * zea mays 63700.0 1 PMID:20221689 -5.2.1.2 * arabidopsis thaliana 50000.0 2 PMID:22980205 -5.2.1.2 * vibrio sp. 36000.0 5 PMID:4692831 -5.2.1.4 * corynebacterium glutamicum 34000.0 4 PMID:16000747;PMID:16481315;PMID:17428791 -5.2.1.4 * klebsiella pneumoniae 30000.0 2 PMID:8760924 -5.2.1.4 * rhodococcus sp. (in: high g+c gram-positive bacteria) 30000.0 2 PMID:21181154 -5.2.1.5 * clostridium sporogenes 190000.0 2 * -5.2.1.5 * lactobacillus acidophilus 67910.0 1 PMID:20461509 -5.2.1.5 * lactobacillus delbrueckii subsp. bulgaricus 41000.0 1 PMID:21340675 -5.2.1.8 * azumapecten farreri 17700.0 1 PMID:18819019 -5.2.1.8 * bacillus subtilis 68000.0 5 PMID:20487272;PMID:9748346 -5.2.1.8 * bombyx mori 21474.0 1 * -5.2.1.8 * bordetella pertussis 27034.0 2 PMID:18164725 -5.2.1.8 * bos taurus 20600.0 1 PMID:8010972 -5.2.1.8 * escherichia coli 62320.0 5 PMID:1606970;PMID:22989269;PMID:26944658;PMID:29632827 -5.2.1.8 * gallus gallus 68000.0 1 PMID:9461498 -5.2.1.8 * geobacillus stearothermophilus 18000.0 1 PMID:1702215 -5.2.1.8 * haemaphysalis longicornis 24000.0 3 * -5.2.1.8 * haemonchus contortus 32500.0 1 PMID:15830208 -5.2.1.8 * halobacterium salinarum 200000.0 3 PMID:11054562 -5.2.1.8 * homo sapiens 18000.0 4 PMID:19369196;PMID:20110589;PMID:3522572 -5.2.1.8 * legionella pneumophila 17968.0 2 PMID:8898384 -5.2.1.8 * lupinus luteus 18000.0 1 PMID:18782068 -5.2.1.8 * methanothermococcus thermolithotrophicus 42000.0 2 PMID:9440528 -5.2.1.8 * mus musculus 14000.0 1 PMID:19369196 -5.2.1.8 * mycobacterium tuberculosis 19200.0 1 PMID:15479239 -5.2.1.8 * mycoplasmoides genitalium 52330.0 2 PMID:10824113 -5.2.1.8 * neisseria gonorrhoeae 28908.0 1 PMID:16238618 -5.2.1.8 * neurospora crassa 20000.0 1 PMID:2971658 -5.2.1.8 * plasmodium falciparum 34800.0 2 PMID:15664653;PMID:9716503 -5.2.1.8 * rattus norvegicus 22000.0 5 PMID:1587281;PMID:1599421;PMID:20110589 -5.2.1.8 * ricinus communis 22000.0 2 PMID:18594858 -5.2.1.8 * rickettsia prowazekii 30819.0 2 PMID:15230349 -5.2.1.8 * saccharomyces cerevisiae 17200.0 2 PMID:8431466 -5.2.1.8 * solanum lycopersicum 18000.0 1 PMID:1702215 -5.2.1.8 * spinacia oleracea 20000.0 1 PMID:12729913 -5.2.1.8 * triticum aestivum 77000.0 1 PMID:9952466 -5.2.1.8 * trypanosoma cruzi 45400.0 2 PMID:17418434;PMID:20580912 -5.2.1.8 * zea mays 17700.0 3 PMID:8645184 -5.3.1.1 * chlamydomonas reinhardtii 58800.0 3 PMID:24157611 -5.3.1.1 * crocodylus palustris 27000.0 1 PMID:16857018;PMID:9890925 -5.3.1.1 * gallus gallus 25000.0 1 PMID:7144592 -5.3.1.1 * geobacillus stearothermophilus 27000.0 1 PMID:15146481;PMID:21396445;PMID:5131007 -5.3.1.1 * giardia duodenalis 108000.0 4 PMID:15146481;PMID:21396445;PMID:5131007 -5.3.1.1 * helicobacter pylori 56000.0 2 PMID:17957775;PMID:5169140 -5.3.1.1 * homo sapiens 56000.0 4 PMID:17957775;PMID:19583769;PMID:21738601;PMID:22342510;PMID:26618356;PMID:507849;PMID:5169140 -5.3.1.1 * lactuca sativa 27000.0 1 PMID:16663420 -5.3.1.1 * leishmania donovani 54000.0 3 PMID:19583769;PMID:21365180;PMID:21738601;PMID:22342510;PMID:26618356 -5.3.1.1 * leishmania mexicana 44800.0 2 PMID:10600459;PMID:8125090 -5.3.1.1 * litchi chinensis 28000.0 1 * -5.3.1.1 * methanobacterium bryantii 57000.0 1 PMID:8925906 -5.3.1.1 * methanococcoides burtonii 160000.0 1 PMID:23328412 -5.3.1.1 * methanothermus fervidus 100000.0 2 PMID:8925906 -5.3.1.1 * mycobacterium tuberculosis 66000.0 4 PMID:16978361 -5.3.1.1 * oryctolagus cuniculus 56000.0 3 PMID:236473;PMID:7144592 -5.3.1.1 * plasmodium falciparum 55663.0 6 PMID:16857018;PMID:19261703;PMID:19583769;PMID:21738601;PMID:22342510;PMID:26618356;PMID:26919806;PMID:9890925 -5.3.1.1 * pteris vittata 43000.0 1 PMID:16941209 -5.3.1.1 * pyrococcus furiosus 25000.0 1 PMID:25824038 -5.3.1.1 * pyrococcus woesei 99600.0 3 PMID:10089525;PMID:8925906 -5.3.1.1 * rhipicephalus microplus 27188.0 2 PMID:15146481;PMID:21396445;PMID:5131007 -5.3.1.1 * saccharolobus solfataricus 25000.0 1 PMID:23865479 -5.3.1.1 * saccharomyces cerevisiae 56000.0 2 PMID:17957775;PMID:5169140 -5.3.1.1 * schistosoma japonicum 28000.0 1 PMID:10600459;PMID:8125090 -5.3.1.1 * secale cereale 54000.0 4 * -5.3.1.1 * spinacia oleracea 27000.0 1 PMID:16663420 -5.3.1.1 * staphylococcus aureus 30000.0 1 PMID:19423633 -5.3.1.1 * thermococcus onnurineus 25000.0 1 PMID:25824038 -5.3.1.1 * trichomonas vaginalis 54000.0 1 PMID:19583769;PMID:21738601;PMID:22342510;PMID:26618356 -5.3.1.1 * trypanosoma brucei 53300.0 3 PMID:11914068;PMID:8108439;PMID:9249046 -5.3.1.1 * trypanosoma cruzi 50000.0 2 PMID:9108237 -5.3.1.12 * halalkalibacterium halodurans 49000.0 1 PMID:18171028 -5.3.1.13 * bacteroides fragilis 85900.0 1 PMID:24891442 -5.3.1.13 * clostridium tetani 109200.0 1 PMID:28630128 -5.3.1.13 * escherichia coli 145000.0 13 PMID:12805358;PMID:15491279;PMID:16199563;PMID:16390329;PMID:20954237;PMID:21498648;PMID:6429331 -5.3.1.13 * pseudomonas aeruginosa 34067.0 2 PMID:21337483 -5.3.1.14 * aeribacillus pallidus 47636.0 2 PMID:17653540 -5.3.1.14 * bacillus subtilis 194000.0 1 * -5.3.1.14 * caldicellulosiruptor obsidiansis 112000.0 1 PMID:28960307 -5.3.1.14 * caldicellulosiruptor saccharolyticus 193400.0 4 PMID:21761877 -5.3.1.14 * dictyoglomus turgidum 185000.0 3 PMID:23070627 -5.3.1.14 * escherichia coli 47000.0 1 PMID:1650346 -5.3.1.14 * halalkalibacterium halodurans 121000.0 4 PMID:20516598;PMID:20822145;PMID:20852996 -5.3.1.14 * mesorhizobium loti 46946.0 1 PMID:21597169 -5.3.1.14 * pseudomonas sp. 150000.0 2 * -5.3.1.14 * stutzerimonas stutzeri 47681.0 4 PMID:15184124;PMID:15342115;PMID:16754978 -5.3.1.14 * thermoanaerobacterium saccharolyticum 48960.0 2 PMID:20516598;PMID:20822145 -5.3.1.14 * thermoclostridium stercorarium subsp. stercorarium 154000.0 1 PMID:29124517 -5.3.1.14 * thermotoga maritima 184000.0 3 PMID:20809285 -5.3.1.15 * bacillus licheniformis 19500.0 1 PMID:21421786 -5.3.1.15 * caldanaerobius polysaccharolyticus 42000.0 1 PMID:32527523 -5.3.1.15 * cohnella laeviribosi 42000.0 1 PMID:17189362 -5.3.1.15 * dictyoglomus turgidum 44000.0 2 PMID:20541111;PMID:22350292 -5.3.1.15 * escherichia coli 39000.0 1 PMID:29392387 -5.3.1.15 * klebsiella aerogenes 40000.0 1 PMID:14304839 -5.3.1.15 * paenibacillus baekrokdamisoli 190000.0 1 * -5.3.1.15 * providencia stuartii 44000.0 4 PMID:20541111;PMID:22350292;PMID:29392387 -5.3.1.15 * serratia proteamaculans 54000.0 3 PMID:20695994 -5.3.1.15 * thermofilum sp. ex4484_79 46000.0 1 PMID:34422783 -5.3.1.15 * thermoflavimicrobium dichotomicum 44500.0 1 * -5.3.1.15 * thermoprotei archaeon 42000.0 1 PMID:32750472 -5.3.1.15 * thermosediminibacter oceani 44000.0 1 PMID:20541111;PMID:22350292 -5.3.1.16 * arabidopsis thaliana 33363.0 1 PMID:9747713 -5.3.1.16 * escherichia coli 27400.0 1 PMID:12356303 -5.3.1.16 * salmonella enterica subsp. enterica serovar typhimurium 29500.0 3 PMID:4959618;PMID:5330429 -5.3.1.16 * thermotoga maritima 27723.0 2 PMID:10413084;PMID:12356303 -5.3.1.17 * escherichia coli 290000.0 6 PMID:16152643;PMID:21664227;PMID:27227414 -5.3.1.20 * mycolicibacterium smegmatis 174000.0 1 PMID:240851 -5.3.1.21 * mesocricetus auratus 389000.0 1 PMID:901753 -5.3.1.21 * rattus norvegicus 44000.0 2 PMID:2322553 -5.3.1.22 * metabacillus fastidiosus 265000.0 2 PMID:7448201 -5.3.1.23 * bacillus subtilis 76000.0 1 PMID:17690466 -5.3.1.23 * pyrococcus horikoshii 80000.0 1 PMID:30471343 -5.3.1.24 * aeromonas caviae 45000.0 1 PMID:1116988 -5.3.1.24 * bacillus subtilis 26300.0 2 PMID:110789 -5.3.1.24 * citrobacter freundii 47000.0 1 PMID:1116988 -5.3.1.24 * corynebacterium glutamicum 110000.0 1 PMID:34657425 -5.3.1.24 * escherichia coli 49800.0 12 PMID:18674541;PMID:19233201;PMID:21354426;PMID:3298981;PMID:391279;PMID:7727400 -5.3.1.24 * geobacillus thermopakistaniensis 50000.0 1 PMID:31669755 -5.3.1.24 * neurospora crassa 160000.0 2 PMID:2946679;PMID:4265643 -5.3.1.24 * ogataea henricii 185000.0 1 * -5.3.1.24 * pectobacterium carotovorum 48000.0 1 PMID:1116988;PMID:4559725 -5.3.1.24 * proteus vulgaris 53000.0 1 PMID:1116988 -5.3.1.24 * saccharomyces cerevisiae 23000.0 1 PMID:3286643 -5.3.1.24 * salmonella enterica subsp. enterica serovar typhimurium 49400.0 1 PMID:3298981 -5.3.1.24 * serratia marcescens 49400.0 2 PMID:1116988;PMID:3298981;PMID:4559725 -5.3.1.24 * serratia rubidaea 45000.0 1 PMID:1116988 -5.3.1.24 * thermotoga maritima 49600.0 3 PMID:10745009;PMID:11265469;PMID:8897600 -5.3.1.25 * caldanaerobius polysaccharolyticus 214000.0 2 PMID:31778693;PMID:32061850 -5.3.1.25 * caldicellulosiruptor saccharolyticus 204000.0 3 PMID:19856146 -5.3.1.25 * dictyoglomus turgidum 410000.0 3 PMID:22627384 -5.3.1.25 * escherichia coli 390000.0 6 PMID:4632320;PMID:9367760 -5.3.1.25 * halothermothrix orenii 204000.0 1 * -5.3.1.25 * klebsiella aerogenes 250000.0 1 PMID:236476 -5.3.1.26 * lacticaseibacillus rhamnosus 19000.0 2 PMID:24015281 -5.3.1.26 * lactococcus lactis 135500.0 5 PMID:17868944;PMID:1901863 -5.3.1.26 * staphylococcus aureus 100000.0 1 PMID:7144590;PMID:7410391 -5.3.1.27 * methylococcus capsulatus 67000.0 1 PMID:4219834 -5.3.1.27 * methylotuvimicrobium alcaliphilum 70000.0 2 PMID:28320301 -5.3.1.27 * mycobacterium gastri 94000.0 3 PMID:17520247 -5.3.1.27 * pyrococcus horikoshii 162000.0 5 PMID:15901685 -5.3.1.28 * aneurinibacillus thermoaerophilus 25000.0 2 PMID:11279237 -5.3.1.28 * burkholderia pseudomallei 22000.0 1 PMID:19923728 -5.3.1.28 * escherichia coli 80000.0 3 PMID:12101286;PMID:8631969 -5.3.1.28 * helicobacter pylori 40500.0 1 PMID:27369071 -5.3.1.28 * mycobacterium tuberculosis 93200.0 1 PMID:33257730 -5.3.1.3 * aeribacillus pallidus 67000.0 1 PMID:18931442 -5.3.1.3 * caldicellulosiruptor saccharolyticus 204000.0 3 PMID:19856146 -5.3.1.3 * escherichia coli 390000.0 6 PMID:4632320;PMID:9367760 -5.3.1.3 * klebsiella aerogenes 250000.0 2 PMID:17189171;PMID:236476 -5.3.1.3 * thermanaeromonas toyohensis 310000.0 1 PMID:31615684 -5.3.1.34 * bos taurus 43000.0 2 PMID:3987693 -5.3.1.4 * acidothermus cellulolyticus 55000.0 2 PMID:19921180 -5.3.1.4 * alicyclobacillus acidocaldarius 224000.0 3 PMID:15639234;PMID:16332764 -5.3.1.4 * anoxybacillus flavithermus 55876.0 1 PMID:21516359 -5.3.1.4 * arthrobacter sp. 335000.0 3 PMID:22917022;PMID:24220791 -5.3.1.4 * bacillus licheniformis 113000.0 3 PMID:18716768 -5.3.1.4 * bacillus subtilis 115000.0 2 PMID:19727704 -5.3.1.4 * bifidobacterium longum 55000.0 1 PMID:22763951 -5.3.1.4 * enterococcus faecium 311000.0 9 PMID:29211024;PMID:33502742 -5.3.1.4 * escherichia coli 362000.0 6 PMID:15248040;PMID:16756997;PMID:236474;PMID:348696 -5.3.1.4 * geobacillus kaustophilus 336000.0 4 PMID:24419630;PMID:26946941 -5.3.1.4 * geobacillus stearothermophilus 225000.0 15 PMID:15639234;PMID:16084621;PMID:16332764;PMID:16386851;PMID:16834609;PMID:17337581;PMID:20474051;PMID:22103589;PMID:22806043;PMID:30282606 -5.3.1.4 * geobacillus thermodenitrificans 230000.0 3 PMID:16084621;PMID:16386851 -5.3.1.4 * halalkalibacterium halodurans 225000.0 5 PMID:15639234;PMID:16332764 -5.3.1.4 * heyndrickxia coagulans 56000.0 2 PMID:22806043 -5.3.1.4 * klebsiella pneumoniae subsp. pneumoniae 336000.0 1 * -5.3.1.4 * lactiplantibacillus plantarum 59600.0 2 PMID:18031349 -5.3.1.4 * lactobacillus gayonii 271000.0 1 PMID:236475;PMID:5773448 -5.3.1.4 * latilactobacillus sakei 220000.0 3 PMID:15168095;PMID:20688514 -5.3.1.4 * levilactobacillus brevis 60100.0 1 PMID:30251190 -5.3.1.4 * limosilactobacillus fermentum 329000.0 4 PMID:22917022;PMID:24220791;PMID:25615964 -5.3.1.4 * parageobacillus thermoglucosidasius 72000.0 2 PMID:23391919 -5.3.1.4 * salmonella enterica subsp. enterica serovar typhimurium 55814.0 1 PMID:3891513 -5.3.1.4 * thermoanaerobacter mathranii 220000.0 4 PMID:15168095;PMID:20688514;PMID:22038246 -5.3.1.4 * thermoanaerobacterium saccharolyticum 233000.0 5 * -5.3.1.4 * thermotoga maritima 230000.0 6 PMID:15006759;PMID:15168095;PMID:22103589 -5.3.1.4 * thermotoga neapolitana 56677.0 1 PMID:12076797 -5.3.1.5 * arthrobacter sp. 47000.0 1 PMID:1854338 -5.3.1.5 * bacillus sp. (in: firmicutes) 160000.0 6 PMID:16349464 -5.3.1.5 * bacteroides thetaiotaomicron 50000.0 1 PMID:21072563;PMID:24100564 -5.3.1.5 * bifidobacterium adolescentis 200000.0 4 PMID:23695585;PMID:7764860;PMID:8830690 -5.3.1.5 * deamia testudo 68000.0 2 PMID:21442549 -5.3.1.5 * escherichia coli 96000.0 3 PMID:16243589 -5.3.1.5 * geobacillus stearothermophilus 130000.0 2 * -5.3.1.5 * heyndrickxia coagulans 49000.0 2 * -5.3.1.5 * hordeum vulgare 100000.0 3 PMID:8620879 -5.3.1.5 * lactococcus lactis 49700.0 2 PMID:15240315 -5.3.1.5 * lactococcus lactis subsp. lactis 183000.0 2 * -5.3.1.5 * levilactobacillus brevis 197000.0 1 PMID:236477 -5.3.1.5 * limosilactobacillus reuteri 190000.0 2 PMID:21519808;PMID:24443973 -5.3.1.5 * opuntia ficus-indica 71000.0 3 PMID:21253889 -5.3.1.5 * opuntia vulgaris 71000.0 3 PMID:21253889 -5.3.1.5 * orpinomyces sp. 108000.0 2 PMID:19050860 -5.3.1.5 * streptomyces albus 165000.0 2 PMID:1176450 -5.3.1.5 * streptomyces coelicolor 46000.0 1 PMID:16243589 -5.3.1.5 * streptomyces corchorusii 180000.0 4 PMID:15765055 -5.3.1.5 * streptomyces flavogriseus 171000.0 2 PMID:16345476 -5.3.1.5 * streptomyces olivochromogenes 117000.0 2 * -5.3.1.5 * streptomyces pseudogriseolus 160000.0 1 PMID:14747699 -5.3.1.5 * streptomyces sp. 183000.0 2 * -5.3.1.5 * thermoanaerobacter ethanolicus 50000.0 1 PMID:21072563;PMID:24100564 -5.3.1.5 * thermoanaerobacterium saccharolyticum 200000.0 2 PMID:23695585;PMID:8830690 -5.3.1.5 * thermotoga neapolitana 210000.0 4 PMID:15752361;PMID:9647799 -5.3.1.5 * thermus aquaticus 196000.0 2 PMID:8830690 -5.3.1.5 * thermus thermophilus 44000.0 1 PMID:22586153 -5.3.1.5 * vibrio sp. 190000.0 3 PMID:21519808;PMID:24443973 -5.3.1.6 * [bacillus] caldolyticus 40000.0 1 PMID:7144591;PMID:956158 -5.3.1.6 * acetivibrio thermocellus 35000.0 6 PMID:18984017;PMID:19923736;PMID:21253719;PMID:32533303;PMID:33394147 -5.3.1.6 * anaplasma phagocytophilum 32000.0 1 PMID:33394147 -5.3.1.6 * bos taurus 228000.0 2 * -5.3.1.6 * brucella anthropi 72000.0 1 PMID:29913551 -5.3.1.6 * brucella melitensis 34000.0 1 PMID:32533303;PMID:33394147 -5.3.1.6 * caldanaerobacter subterraneus 35000.0 1 PMID:33394147 -5.3.1.6 * chromatium sp. 54000.0 1 PMID:7144591 -5.3.1.6 * clostridioides difficile 34400.0 2 PMID:20155483;PMID:32533303 -5.3.1.6 * coccidioides immitis 37000.0 1 PMID:33394147 -5.3.1.6 * cyberlindnera jadinii 183000.0 5 PMID:4773875 -5.3.1.6 * escherichia coli 50000.0 4 PMID:1104357;PMID:12211039;PMID:33394147 -5.3.1.6 * giardia duodenalis 33000.0 1 PMID:33394147 -5.3.1.6 * lathyrus oleraceus 26400.0 1 PMID:16668459 -5.3.1.6 * leishmania infantum 74000.0 1 PMID:33394147 -5.3.1.6 * mycobacterium tuberculosis 35000.0 5 PMID:14687575;PMID:32533303;PMID:33394147 -5.3.1.6 * mycoplasmoides genitalium 17000.0 1 PMID:33394147 -5.3.1.6 * pseudothermotoga lettingae 35200.0 4 PMID:23386225;PMID:32533303 -5.3.1.6 * pyrococcus horikoshii 98000.0 3 PMID:12057201 -5.3.1.6 * rhodospirillum rubrum 57000.0 1 * -5.3.1.6 * spinacia oleracea 53000.0 6 PMID:10620366;PMID:8624410 -5.3.1.6 * streptococcus mutans 24570.0 2 PMID:22691789 -5.3.1.6 * streptococcus pneumoniae 96000.0 3 * -5.3.1.6 * thermotoga maritima 67000.0 5 PMID:15162497;PMID:20155483;PMID:22333529;PMID:33394147 -5.3.1.6 * thiobacillus thioparus 40000.0 1 PMID:7144591;PMID:956158 -5.3.1.6 * trypanosoma brucei 68000.0 1 PMID:33394147 -5.3.1.6 * trypanosoma cruzi 70000.0 5 PMID:16981853;PMID:33394147 -5.3.1.6 * vibrio vulnificus 45000.0 1 PMID:19214439 -5.3.1.7 * agrobacterium tumefaciens 90000.0 2 PMID:11330684 -5.3.1.7 * escherichia coli 274500.0 3 PMID:27138861;PMID:7033464;PMID:796410 -5.3.1.7 * gluconobacter thailandicus 196000.0 1 PMID:35700128 -5.3.1.7 * marinomonas mediterranea 42000.0 1 PMID:29107017 -5.3.1.7 * pseudomonas syringae 40500.0 1 PMID:33484446 -5.3.1.7 * thermosediminibacter oceani 44000.0 1 * -5.3.1.8 * aeropyrum pernix 45000.0 3 PMID:14551194 -5.3.1.8 * amorphophallus konjac 45000.0 1 PMID:14551194 -5.3.1.8 * bacillus amyloliquefaciens 35000.0 1 PMID:26171785 -5.3.1.8 * bacillus subtilis 36600.0 3 PMID:19447949 -5.3.1.8 * burkholderia cenocepacia 56000.0 2 PMID:18668237 -5.3.1.8 * burkholderia cepacia 55300.0 2 PMID:17184737 -5.3.1.8 * candida albicans 49060.0 2 PMID:7601089 -5.3.1.8 * cassia coluteoides 74500.0 3 * -5.3.1.8 * cyamopsis tetragonoloba 54000.0 1 * -5.3.1.8 * escherichia coli 61000.0 1 PMID:2549364 -5.3.1.8 * geobacillus thermodenitrificans 36452.0 2 PMID:19390787 -5.3.1.8 * glycine max 59000.0 1 * -5.3.1.8 * homo sapiens 46530.0 2 PMID:8307007 -5.3.1.8 * pseudomonas aeruginosa 56000.0 3 PMID:1846611;PMID:2426246 -5.3.1.8 * pyrobaculum aerophilum 65000.0 3 PMID:15290326 -5.3.1.8 * pyrococcus furiosus 53000.0 1 PMID:19421452 -5.3.1.8 * pyrococcus horikoshii 52900.0 1 PMID:26290359 -5.3.1.8 * sphingobium chungbukense 50000.0 1 PMID:19712590 -5.3.1.8 * thermoplasma acidophilum 67000.0 4 PMID:14551194 -5.3.1.8 * thermus thermophilus 29100.0 5 PMID:21115698;PMID:21729734 -5.3.1.8 * trigonella foenum-graecum 63000.0 1 * -5.3.1.8 * xanthomonas campestris 58000.0 1 PMID:9450661 -5.3.1.9 * [bacillus] caldotenax 204000.0 2 PMID:7400125 -5.3.1.9 * acetivibrio thermocellus 49000.0 1 PMID:21630486 -5.3.1.9 * aeropyrum pernix 45000.0 3 PMID:14551194 -5.3.1.9 * archaeoglobus fulgidus 28000.0 3 PMID:15716432 -5.3.1.9 * bos taurus 118000.0 3 PMID:3369868 -5.3.1.9 * brassica oleracea 140000.0 2 PMID:16662282 -5.3.1.9 * carassius auratus 120000.0 3 PMID:16212940;PMID:19472999 -5.3.1.9 * cassia coluteoides 127000.0 1 * -5.3.1.9 * clarkia xantiana 125000.0 1 PMID:16662282 -5.3.1.9 * cyamopsis tetragonoloba 96000.0 1 * -5.3.1.9 * drosophila melanogaster 127000.0 2 PMID:6815424 -5.3.1.9 * dunaliella salina 75000.0 2 PMID:19688275 -5.3.1.9 * escherichia coli 234000.0 4 PMID:7004378 -5.3.1.9 * geobacillus stearothermophilus 172000.0 1 PMID:236463 -5.3.1.9 * glycine max 128000.0 1 * -5.3.1.9 * helianthus annuus 140000.0 2 PMID:16662282 -5.3.1.9 * homo sapiens 132000.0 12 PMID:1128273;PMID:15059907;PMID:2241164;PMID:3191476;PMID:5135316 -5.3.1.9 * lacticaseibacillus casei 135000.0 4 PMID:6251893 -5.3.1.9 * lathyrus oleraceus 120000.0 3 PMID:236464;PMID:6814363 -5.3.1.9 * leishmania mexicana mexicana 110000.0 2 PMID:4722497;PMID:7870131 -5.3.1.9 * methanocaldococcus jannaschii 80000.0 2 PMID:14655001 -5.3.1.9 * methanosarcina mazei 30209.0 2 PMID:15716432 -5.3.1.9 * mus musculus 120000.0 3 PMID:4722497;PMID:6815424;PMID:7870131 -5.3.1.9 * mycobacterium tuberculosis 120000.0 3 PMID:16212940;PMID:19472999 -5.3.1.9 * oryctolagus cuniculus 140000.0 1 * -5.3.1.9 * plasmodium falciparum 66000.0 2 PMID:1435856;PMID:20208175 -5.3.1.9 * pyrobaculum aerophilum 65000.0 3 PMID:15290326 -5.3.1.9 * pyrococcus furiosus 49600.0 8 PMID:11344151;PMID:11533028;PMID:19159927 -5.3.1.9 * saccharomyces cerevisiae 145000.0 5 PMID:3072254;PMID:4602031;PMID:6987143 -5.3.1.9 * salmonella enterica 67000.0 3 PMID:15716432 -5.3.1.9 * sinorhizobium meliloti 43000.0 3 PMID:15716432 -5.3.1.9 * spinacia oleracea 140000.0 5 PMID:16662282;PMID:236464;PMID:4421522;PMID:6814363 -5.3.1.9 * sus scrofa 132000.0 1 PMID:7431408 -5.3.1.9 * thermococcus kodakarensis 24675.0 2 * -5.3.1.9 * thermoplasma acidophilum 67000.0 4 PMID:14551194 -5.3.1.9 * trigonella foenum-graecum 104000.0 1 * -5.3.1.9 * triticum aestivum 130000.0 1 PMID:2341161 -5.3.1.9 * trypanosoma brucei 105000.0 1 PMID:2940090 -5.3.1.9 * trypanosoma cruzi 116000.0 1 PMID:3527272 -5.3.2.1 * bos taurus 12000.0 1 PMID:16457622;PMID:9395080 -5.3.2.1 * brugia malayi 13100.0 1 PMID:12221083 -5.3.2.1 * homo sapiens 36000.0 3 PMID:10353846;PMID:16457622;PMID:30195326;PMID:9395080 -5.3.2.1 * mus musculus 12371.0 2 PMID:10625471;PMID:10933783 -5.3.2.1 * mycolicibacterium smegmatis 48000.0 3 PMID:21370851 -5.3.2.1 * sus scrofa 44000.0 1 PMID:5824560 -5.3.2.2 * bos taurus 80000.0 4 PMID:2624174;PMID:3179281 -5.3.2.2 * sus scrofa 55000.0 1 PMID:3957907 -5.3.2.3 * streptomyces ravidus 19100.0 1 PMID:21264378 -5.3.2.4 * streptomyces fradiae 31000.0 3 PMID:17209568 -5.3.2.5 * klebsiella pneumoniae 28300.0 2 PMID:8227039 -5.3.2.6 * burkholderia lata 39640.0 2 PMID:31074977 -5.3.2.6 * chloroflexus aurantiacus 8096.0 3 PMID:20465238 -5.3.2.6 * escherichia coli 14000.0 1 * -5.3.2.6 * gammaproteobacteria bacterium 42720.0 2 PMID:34019384 -5.3.2.6 * pseudomonas putida 10000.0 1 PMID:23759430 -5.3.2.7 * anthracobia melaloma 140000.0 3 PMID:15110094;PMID:16822618 -5.3.2.7 * phanerodontia chrysosporium 98746.0 2 PMID:22330145 -5.3.2.8 * pseudomonas putida 37600.0 1 PMID:21219457 -5.3.3.1 * bos taurus 81000.0 2 PMID:1562558 -5.3.3.1 * comamonas testosteroni 68000.0 8 PMID:1141206;PMID:14454546;PMID:237889 -5.3.3.1 * homo sapiens 77000.0 6 PMID:11463578;PMID:2770297;PMID:3199818 -5.3.3.1 * macaca mulatta 41874.0 1 PMID:2050270 -5.3.3.1 * ovis aries 300000.0 2 PMID:4274151 -5.3.3.1 * pseudomonas putida 27700.0 2 PMID:7358699 -5.3.3.1 * rattus norvegicus 46800.0 1 PMID:2945972 -5.3.3.10 * escherichia coli 30000.0 3 PMID:2194841 -5.3.3.10 * pseudomonas putida 38000.0 1 * -5.3.3.11 * mentha x piperita 54000.0 1 PMID:3885858 -5.3.3.12 * mus musculus 300000.0 2 PMID:2169885 -5.3.3.12 * sepia officinalis 85000.0 1 PMID:8192674 -5.3.3.13 * ptilota filicina 174000.0 8 PMID:12054482;PMID:7803384;PMID:9062129 -5.3.3.14 * escherichia coli 36000.0 5 PMID:2832401;PMID:4863739;PMID:4900506 -5.3.3.14 * streptococcus pneumoniae 129000.0 2 PMID:12237320 -5.3.3.17 * pseudomonas fluorescens 66070.0 4 PMID:14684924;PMID:15449932;PMID:15545603 -5.3.3.18 * thermus thermophilus 30000.0 2 PMID:22961985 -5.3.3.2 * aedes aegypti 28500.0 1 PMID:22782071 -5.3.3.2 * bacillus subtilis 45000.0 4 PMID:12798687;PMID:15206931 -5.3.3.2 * bombyx mori 35000.0 1 PMID:3740842;PMID:4066649 -5.3.3.2 * capsicum annuum 33500.0 1 * -5.3.3.2 * catharanthus roseus 35000.0 1 PMID:22638903;PMID:23747531 -5.3.3.2 * choristoneura fumiferana 29200.0 1 PMID:22820710 -5.3.3.2 * cinchona robusta 34000.0 2 PMID:9363768 -5.3.3.2 * claviceps sp. 35000.0 1 PMID:3740842;PMID:4066649 -5.3.3.2 * escherichia coli 24500.0 2 PMID:11173482;PMID:22503704 -5.3.3.2 * gossypium barbadense 34390.0 1 PMID:19055484 -5.3.3.2 * homo sapiens 26300.0 1 PMID:22503704 -5.3.3.2 * ipomoea batatas 33800.0 1 * -5.3.3.2 * manduca sexta 29200.0 1 PMID:22820710 -5.3.3.2 * methanocaldococcus jannaschii 40000.0 2 PMID:16793276;PMID:21206036 -5.3.3.2 * methanothermobacter thermautotrophicus 48000.0 1 PMID:14996812 -5.3.3.2 * populus trichocarpa 35000.0 1 PMID:22638903;PMID:23747531 -5.3.3.2 * pyrococcus furiosus 197000.0 2 PMID:18076031 -5.3.3.2 * saccharomyces cerevisiae 33350.0 1 PMID:2681212 -5.3.3.2 * schizosaccharomyces pombe 26864.0 1 PMID:7744766 -5.3.3.2 * solanum lycopersicum 34000.0 3 PMID:4021816;PMID:6324686 -5.3.3.2 * streptococcus pneumoniae 173600.0 1 PMID:24910111 -5.3.3.2 * sus scrofa 82500.0 1 PMID:202196 -5.3.3.2 * synechocystis sp. 50000.0 1 PMID:15547291 -5.3.3.2 * thermococcus kodakarensis 345000.0 2 PMID:15882994 -5.3.3.21 * rattus norvegicus 200000.0 3 PMID:8068693;PMID:8300563;PMID:9417087 -5.3.3.3 * clostridium aminobutyricum 232000.0 2 PMID:8344309 -5.3.3.3 * clostridium kluyveri 237000.0 2 PMID:8161284 -5.3.3.3 * pseudomonas fragi 240000.0 1 PMID:2361950 -5.3.3.4 * acinetobacter calcoaceticus 100000.0 2 PMID:16156722;PMID:4199894;PMID:4215816 -5.3.3.4 * cupriavidus necator 89000.0 3 PMID:8647072;PMID:9211711 -5.3.3.4 * pseudomonas putida 111000.0 8 PMID:4032480;PMID:4199894;PMID:4215816;PMID:454663;PMID:5330966 -5.3.3.4 * pseudomonas reinekei 10000.0 1 PMID:20061479 -5.3.3.4 * rhodococcus sp. (in: high g+c gram-positive bacteria) 100000.0 2 PMID:16156722;PMID:4215816 -5.3.3.5 * arabidopsis thaliana 26737.0 2 PMID:11171067;PMID:9862498 -5.3.3.5 * homo sapiens 107000.0 4 PMID:12133002;PMID:19053780 -5.3.3.5 * rattus norvegicus 26737.0 1 PMID:11171067;PMID:9862498 -5.3.3.6 * eubacterium barkeri 140000.0 4 PMID:19559030;PMID:5574401 -5.3.3.7 * pseudomonas putida 78000.0 1 PMID:5114987 -5.3.3.7 * pseudomonas sp. wu-0701 25300.0 1 PMID:26293748 -5.3.3.7 * zea mays 80000.0 1 * -5.3.3.8 * arabidopsis thaliana 26000.0 1 PMID:18657232 -5.3.3.8 * bos taurus 60000.0 3 PMID:12356468;PMID:2154476;PMID:2222859;PMID:376522 -5.3.3.8 * cucumis sativus 50000.0 2 PMID:2013292 -5.3.3.8 * escherichia coli 260000.0 3 PMID:7012144 -5.3.3.8 * homo sapiens 78000.0 9 PMID:10419495;PMID:18416831;PMID:2154476;PMID:8198519;PMID:8486162 -5.3.3.8 * mus musculus 75000.0 2 PMID:10419495;PMID:7953067 -5.3.3.8 * rattus norvegicus 200000.0 15 PMID:12356468;PMID:1438379;PMID:1543742;PMID:1958319;PMID:2040594;PMID:2154476;PMID:2222859;PMID:2303409;PMID:2375752;PMID:376522;PMID:738702 -5.3.3.8 * saccharomyces cerevisiae 170000.0 3 PMID:14741345 -5.3.3.8 * sus scrofa 91000.0 4 PMID:12356468;PMID:2154476;PMID:2222859;PMID:376522 -5.3.3.9 * oryctolagus cuniculus 115000.0 3 PMID:1137404;PMID:4420472 -5.3.4.1 * amblyomma variegatum 55000.0 1 PMID:16507355;PMID:17098169;PMID:17639131;PMID:1915081;PMID:21471526;PMID:22401853;PMID:22685557;PMID:2776749 -5.3.4.1 * angiostrongylus cantonensis 57000.0 2 PMID:22218922;PMID:2619767;PMID:7236202 -5.3.4.1 * arabidopsis thaliana 220000.0 2 * -5.3.4.1 * aspergillus niger 54300.0 1 PMID:9021130 -5.3.4.1 * bos taurus 110000.0 6 PMID:16507355;PMID:17098169;PMID:17639131;PMID:1915081;PMID:21471526;PMID:22218922;PMID:22401853;PMID:22685557;PMID:2619767;PMID:2776749;PMID:6503714;PMID:6615424;PMID:7236202;PMID:9534150 -5.3.4.1 * chlamydomonas reinhardtii 120000.0 4 PMID:2344363;PMID:23475997;PMID:7764266;PMID:7775391;PMID:9534150 -5.3.4.1 * conus amadis 55000.0 1 PMID:16507355;PMID:17098169;PMID:17639131;PMID:1915081;PMID:21471526;PMID:22401853;PMID:22685557;PMID:2776749 -5.3.4.1 * dickeya chrysanthemi 25910.0 1 PMID:8168497 -5.3.4.1 * escherichia coli 21100.0 2 PMID:8411164 -5.3.4.1 * gallus gallus 140000.0 2 PMID:2081737;PMID:6144305 -5.3.4.1 * giardia duodenalis 50430.0 4 PMID:10514458 -5.3.4.1 * glycine max 300000.0 6 PMID:18422652;PMID:19583593;PMID:2344363;PMID:7764266;PMID:7775391;PMID:9534150 -5.3.4.1 * haemaphysalis longicornis 54890.0 3 PMID:17550821 -5.3.4.1 * homo sapiens 116000.0 14 PMID:10993217;PMID:12761212;PMID:16407203;PMID:16507355;PMID:16940051;PMID:17098169;PMID:17639131;PMID:1915081;PMID:20029959;PMID:21308844;PMID:21471526;PMID:22401853;PMID:22685557;PMID:2776749;PMID:3566712;PMID:7794766;PMID:9873049;PMID:9915866 -5.3.4.1 * leishmania amazonensis 52000.0 4 PMID:18058133 -5.3.4.1 * mesocricetus auratus 55000.0 1 PMID:16507355;PMID:17098169;PMID:17639131;PMID:1915081;PMID:21471526;PMID:22401853;PMID:22685557;PMID:2776749 -5.3.4.1 * mus musculus 65000.0 2 PMID:15475357;PMID:24415753 -5.3.4.1 * mycothermus thermophilus 120000.0 5 PMID:20695532;PMID:2344363;PMID:7764266;PMID:7775391;PMID:9534150 -5.3.4.1 * neospora caninum 55000.0 2 PMID:17720161 -5.3.4.1 * oldenlandia affinis 122000.0 6 PMID:17522051;PMID:18985675 -5.3.4.1 * oryza sativa 208000.0 2 PMID:21278127 -5.3.4.1 * plasmodium chabaudi 85000.0 2 PMID:19615402 -5.3.4.1 * pseudomonas aeruginosa 25000.0 2 PMID:11133952 -5.3.4.1 * rattus norvegicus 326000.0 12 PMID:15169950;PMID:16507355;PMID:16543366;PMID:17098169;PMID:17639131;PMID:1915081;PMID:21471526;PMID:22218922;PMID:22401853;PMID:22685557;PMID:2619767;PMID:2776749;PMID:3566712;PMID:7236202;PMID:9534149 -5.3.4.1 * ricinus communis 100000.0 2 PMID:8631332 -5.3.4.1 * saccharolobus solfataricus 27100.0 2 PMID:17076700 -5.3.4.1 * saccharomyces cerevisiae 140000.0 2 PMID:2081737;PMID:6144305 -5.3.4.1 * schizosaccharomyces pombe 39490.0 1 PMID:16850188 -5.3.4.1 * streptomyces sp. 55000.0 1 PMID:15295108 -5.3.4.1 * sus scrofa 56859.0 2 PMID:20152940 -5.3.4.1 * triticum aestivum 108000.0 1 PMID:15169950 -5.3.4.1 * trypanosoma brucei 80000.0 2 PMID:15642735 -5.3.99.12 * petiveria alliacea 217700.0 1 PMID:19692535 -5.3.99.13 * priestia megaterium 87000.0 1 PMID:35644181 -5.3.99.2 * bos taurus 26000.0 1 PMID:7132774;PMID:9510973 -5.3.99.2 * danio rerio 28600.0 1 PMID:16616995 -5.3.99.2 * gallus gallus 22732.0 1 * -5.3.99.2 * homo sapiens 28000.0 7 PMID:11672424;PMID:16997134;PMID:1902577;PMID:19531375;PMID:20008150;PMID:20074808;PMID:21112970 -5.3.99.2 * mus musculus 26000.0 4 PMID:19531375;PMID:19833210;PMID:20008150;PMID:21112970 -5.3.99.2 * rattus norvegicus 85000.0 9 PMID:109431;PMID:11672424;PMID:18535747;PMID:2642896;PMID:7132774;PMID:7132775;PMID:9510973 -5.3.99.3 * bos taurus 32000.0 3 PMID:15358613;PMID:15744024 -5.3.99.3 * homo sapiens 215000.0 13 PMID:12460774;PMID:12672824;PMID:16399384;PMID:18209033;PMID:18498757;PMID:18635657;PMID:18777160;PMID:18984580;PMID:19017494;PMID:24803849 -5.3.99.3 * macaca fascicularis 17000.0 1 PMID:15301794 -5.3.99.3 * macaca mulatta 16000.0 1 PMID:18209033;PMID:18635657 -5.3.99.3 * ovis aries 180000.0 2 PMID:3100531 -5.3.99.3 * rattus norvegicus 33000.0 2 PMID:15358613;PMID:15744024 -5.3.99.3 * sus scrofa 17300.0 1 PMID:16223862 -5.3.99.4 * bos taurus 56675.0 4 PMID:16115610;PMID:6221581;PMID:6338016;PMID:8051072;PMID:8074709;PMID:8280118 -5.3.99.4 * homo sapiens 57100.0 8 PMID:11879180;PMID:15115769;PMID:15708381;PMID:16115610;PMID:20122998;PMID:20159982 -5.3.99.4 * rattus norvegicus 56500.0 3 PMID:16094316;PMID:19060098;PMID:19344900;PMID:19410579 -5.3.99.4 * sus scrofa 52000.0 2 PMID:19344900;PMID:19410579 -5.3.99.5 * homo sapiens 60000.0 5 PMID:18264100;PMID:20122998;PMID:21371456;PMID:2195994;PMID:2999104 -5.3.99.5 * sus scrofa 53000.0 1 PMID:3745157 -5.3.99.6 * arabidopsis thaliana 65000.0 1 PMID:27135223 -5.3.99.6 * artemisia annua 26610.0 1 * -5.3.99.6 * camptotheca acuminata 26800.0 1 PMID:18847436 -5.3.99.6 * hordeum vulgare 26000.0 2 PMID:15081279 -5.3.99.6 * ipomoea nil 26160.0 3 PMID:19420721 -5.3.99.6 * jatropha curcas 27000.0 2 * -5.3.99.6 * physcomitrium patens 33000.0 4 PMID:20704658 -5.3.99.6 * zea mays 45000.0 1 PMID:3178850 -5.3.99.8 * capsicum annuum 167000.0 4 PMID:20460582;PMID:31505449;PMID:7920703 -5.4.1.3 * chloroflexus aurantiacus 73000.0 2 PMID:19955419 -5.4.2.10 * bacillus anthracis 93100.0 3 PMID:19574653;PMID:21685296 -5.4.2.10 * escherichia coli 47412.0 1 PMID:10231382 -5.4.2.10 * methanococcus maripaludis 340000.0 2 PMID:18263721 -5.4.2.10 * staphylococcus aureus 99462.0 1 PMID:30668586 -5.4.2.10 * streptococcus gordonii 50000.0 2 PMID:18462386 -5.4.2.11 * brucella abortus 52540.0 1 PMID:29302824 -5.4.2.11 * escherichia coli 56300.0 1 PMID:166274 -5.4.2.11 * homo sapiens 56000.0 2 PMID:10303;PMID:186068;PMID:20403181 -5.4.2.11 * lactococcus lactis subsp. lactis 102000.0 2 PMID:20530968 -5.4.2.11 * mus musculus 30500.0 2 PMID:18448067 -5.4.2.11 * mycobacterium tuberculosis 46700.0 2 PMID:16511148 -5.4.2.11 * rattus norvegicus 60000.0 3 PMID:18533197;PMID:2158448;PMID:2844269 -5.4.2.11 * saccharomyces cerevisiae 27000.0 1 * -5.4.2.11 * schizosaccharomyces pombe 27000.0 2 PMID:11237600 -5.4.2.11 * streptomyces coelicolor 120000.0 2 PMID:1530847 -5.4.2.11 * sus scrofa 57000.0 4 PMID:18499067;PMID:6293580 -5.4.2.12 * archaeoglobus fulgidus 48000.0 3 PMID:17576516 -5.4.2.12 * aspergillus nidulans 60000.0 1 PMID:2844142 -5.4.2.12 * brugia malayi 61779.0 2 PMID:10388626;PMID:15234973;PMID:25061608 -5.4.2.12 * caenorhabditis elegans 60000.0 1 PMID:10388626;PMID:15234973 -5.4.2.12 * dirofilaria immitis 57000.0 1 PMID:21324604 -5.4.2.12 * entamoeba histolytica 57000.0 1 * -5.4.2.12 * geobacillus stearothermophilus 60000.0 1 PMID:10388626;PMID:15234973 -5.4.2.12 * leishmania donovani 67.0 1 PMID:28691653 -5.4.2.12 * leishmania mexicana 60724.0 2 PMID:15096219 -5.4.2.12 * methanocaldococcus jannaschii 190600.0 2 PMID:12076796 -5.4.2.12 * neurospora crassa 60000.0 1 * -5.4.2.12 * priestia megaterium 61000.0 1 PMID:33959 -5.4.2.12 * pyrococcus furiosus 183500.0 2 PMID:12076796 -5.4.2.12 * ricinus communis 64500.0 2 PMID:3004361 -5.4.2.12 * saccharolobus solfataricus 46800.0 3 PMID:12644480 -5.4.2.12 * thermoplasma acidophilum 46000.0 3 PMID:17576516 -5.4.2.12 * triticum aestivum 58000.0 2 PMID:19039 -5.4.2.12 * trypanosoma brucei 60557.0 2 PMID:10691985;PMID:22458781 -5.4.2.12 * wolbachia endosymbiont of dirofilaria immitis 56000.0 1 PMID:21324604 -5.4.2.12 * wolbachia sp. 100000.0 2 PMID:19043737 -5.4.2.12 * zea mays 64000.0 1 PMID:2480892 -5.4.2.12 * zymomonas mobilis 52000.0 2 PMID:3026343 -5.4.2.2 * acetivibrio thermocellus 65000.0 2 PMID:19566723 -5.4.2.2 * bacillus subtilis 130000.0 2 PMID:4212311 -5.4.2.2 * fusarium oxysporum 60000.0 2 PMID:22112903;PMID:31356 -5.4.2.2 * homo sapiens 69000.0 2 PMID:2149596;PMID:2533352 -5.4.2.2 * lactococcus lactis 84300.0 6 PMID:16980299;PMID:22949208;PMID:8071206 -5.4.2.2 * lathyrus oleraceus 132000.0 5 PMID:10424900;PMID:9818085 -5.4.2.2 * magallana gigas 61000.0 1 PMID:16876970 -5.4.2.2 * oryctolagus cuniculus 73000.0 3 PMID:1328221 -5.4.2.2 * pseudomonas aeruginosa 52000.0 2 PMID:8050998 -5.4.2.2 * pyrococcus horikoshii 50000.0 1 PMID:16091590 -5.4.2.2 * saccharomyces cerevisiae 65600.0 2 PMID:1100398;PMID:6216393 -5.4.2.2 * salmonella enterica subsp. enterica serovar typhimurium 109600.0 3 PMID:21246636 -5.4.2.2 * senna corymbosa 60000.0 1 * -5.4.2.2 * solanum tuberosum 62000.0 2 PMID:22112903;PMID:31356 -5.4.2.2 * sphingobium chungbukense 59500.0 3 PMID:18664520 -5.4.2.2 * sphingomonas sanxanigenens 49800.0 1 PMID:23546942 -5.4.2.2 * spinacia oleracea 60000.0 1 PMID:24414634 -5.4.2.2 * thermococcus kodakarensis 210000.0 2 PMID:15342576 -5.4.2.2 * trypanosoma cruzi 66000.0 1 PMID:19696235 -5.4.2.2 * zea mays 133000.0 4 PMID:9662542;PMID:9668210;PMID:9818085 -5.4.2.3 * aedes aegypti 60600.0 1 PMID:16313562 -5.4.2.3 * candida albicans 60000.0 1 PMID:16582501 -5.4.2.3 * sus scrofa 64000.0 2 PMID:468829 -5.4.2.4 * homo sapiens 63000.0 9 PMID:129153;PMID:15258155;PMID:163190;PMID:166276;PMID:186068;PMID:4694722 -5.4.2.4 * saccharomyces cerevisiae 120000.0 2 PMID:182494 -5.4.2.6 * bacillus subtilis 80000.0 2 PMID:11081794 -5.4.2.6 * euglena gracilis 27000.0 1 PMID:4212162 -5.4.2.6 * lactobacillus delbrueckii subsp. lactis 34000.0 5 PMID:24391053;PMID:8071206;PMID:9084169 -5.4.2.6 * lactococcus lactis 34000.0 3 PMID:16990434;PMID:8071206 -5.4.2.6 * levilactobacillus brevis 29000.0 1 PMID:6230052 -5.4.2.6 * pyrococcus sp. 25000.0 1 PMID:24391053 -5.4.2.6 * streptococcus mutans 24500.0 1 PMID:24509501 -5.4.2.7 * bacillus cereus 44000.0 2 PMID:20606280;PMID:21193409 -5.4.2.7 * escherichia coli 46000.0 4 PMID:1089430;PMID:19818317;PMID:4992818 -5.4.2.7 * geobacillus stearothermophilus 53000.0 4 PMID:9692190 -5.4.2.7 * lysinibacillus sphaericus 43000.0 1 PMID:19818317 -5.4.2.7 * oryctolagus cuniculus 86000.0 1 PMID:5824563 -5.4.2.7 * rattus norvegicus 65000.0 2 PMID:6297594 -5.4.2.7 * thermococcus kodakarensis 210000.0 1 PMID:15205420 -5.4.2.8 * amorphophallus konjac 62000.0 1 * -5.4.2.8 * arabidopsis thaliana 27700.0 1 PMID:17217471 -5.4.2.8 * homo sapiens 31100.0 3 PMID:16963079;PMID:9271215;PMID:9376685 -5.4.2.8 * leishmania mexicana 31100.0 1 PMID:16963079 -5.4.2.8 * malpighia glabra 27900.0 1 PMID:19122187 -5.4.2.8 * pseudomonas aeruginosa 38000.0 1 * -5.4.2.8 * pyrococcus horikoshii 50000.0 1 PMID:16091590 -5.4.2.8 * rattus norvegicus 60000.0 2 PMID:9271215 -5.4.2.8 * saccharomyces cerevisiae 55000.0 2 PMID:3288631 -5.4.2.8 * senna corymbosa 58000.0 2 * -5.4.2.8 * sphingobium chungbukense 105400.0 2 PMID:18664520 -5.4.2.8 * thermococcus kodakarensis 210000.0 2 PMID:15342576 -5.4.2.9 * burkholderia gladioli 263000.0 3 PMID:1400236 -5.4.2.9 * mytilus edulis 144000.0 2 PMID:9468496 -5.4.2.9 * streptomyces hygroscopicus 67000.0 2 PMID:2160937 -5.4.2.9 * tetrahymena pyriformis 81000.0 6 PMID:1547241;PMID:2121271;PMID:3138545 -5.4.3.2 * bacillus subtilis 224000.0 2 PMID:10839984 -5.4.3.2 * clostridium sp. 285000.0 3 PMID:2019591;PMID:2192619;PMID:5438361;PMID:5452674 -5.4.3.2 * clostridium subterminale 285000.0 5 PMID:10924153;PMID:11123891;PMID:2019591;PMID:2192619;PMID:24308628;PMID:5452674 -5.4.3.2 * methanococcus maripaludis 98000.0 1 PMID:35544775 -5.4.3.3 * acetoanaerobium sticklandii 300000.0 11 PMID:10617592;PMID:24562332;PMID:4540127;PMID:5480154 -5.4.3.3 * porphyromonas gingivalis 300000.0 2 PMID:24562332 -5.4.3.5 * acetoanaerobium sticklandii 210000.0 16 PMID:11577113;PMID:20106986;PMID:21899873;PMID:24562332;PMID:28528213;PMID:4711468 -5.4.3.6 * brevibacillus brevis 75000.0 1 PMID:5021987 -5.4.3.6 * streptomyces globisporus 58100.0 1 PMID:14580219 -5.4.3.8 * acinetobacter baumannii 89000.0 1 PMID:30863751 -5.4.3.8 * brassica napus 88000.0 2 PMID:12767809 -5.4.3.8 * chlamydomonas reinhardtii 43000.0 2 PMID:16663462;PMID:1985889 -5.4.3.8 * hordeum vulgare 500000.0 5 PMID:2349227;PMID:2505791 -5.4.3.8 * lathyrus oleraceus 100000.0 2 PMID:2037071 -5.4.3.8 * propionibacterium freudenreichii 45932.0 1 PMID:8439165 -5.4.3.8 * saccharolobus solfataricus 87000.0 2 PMID:8973563 -5.4.3.8 * synechococcus sp. 98000.0 2 PMID:1910318;PMID:2505791 -5.4.3.8 * xanthomonas campestris 45043.0 1 PMID:7763385 -5.4.4.1 * comamonas sp. 15951.0 1 PMID:16517619 -5.4.4.2 * arabidopsis thaliana 59000.0 1 PMID:17190832 -5.4.4.2 * escherichia coli 98000.0 6 PMID:2139795;PMID:8764478;PMID:9150206 -5.4.4.2 * flavobacterium sp. 45000.0 2 PMID:8229014 -5.4.4.2 * pseudomonas aeruginosa 50000.0 2 PMID:12624097 -5.4.4.3 * cupriavidus necator 62000.0 1 PMID:10049374 -5.4.4.4 * castellaniella defragrans 160000.0 2 PMID:20663876 -5.4.4.5 * aspergillus nidulans 440000.0 2 PMID:19286665 -5.4.4.6 * colletotrichum gloeosporioides 510000.0 1 PMID:26577673 -5.4.4.6 * gaeumannomyces graminis 130000.0 2 PMID:10497176;PMID:10667399 -5.4.4.9 * pelobacter acidigallici 160000.0 7 PMID:10518782;PMID:11807272;PMID:8647079 -5.4.99.1 * clostridium cochlearium 136634.0 1 PMID:35589197 -5.4.99.1 * clostridium tetanomorphum 136912.0 5 PMID:19021770;PMID:35589197;PMID:9739092 -5.4.99.1 * fusobacterium varium 51000.0 2 PMID:21575137 -5.4.99.1 * streptomyces ansochromogenes 48000.0 4 PMID:15885615 -5.4.99.11 * enterobacter sp. fmb-1 70180.0 2 PMID:19486422;PMID:32910357 -5.4.99.11 * erwinia rhapontici 80000.0 4 PMID:20589449;PMID:21229265 -5.4.99.11 * erwinia sp. 65000.0 1 * -5.4.99.11 * erwinia sp. ejp617 70000.0 1 PMID:19486422;PMID:32910357 -5.4.99.11 * klebsiella pneumoniae 69980.0 2 * -5.4.99.11 * klebsiella sp. lx3 66000.0 1 PMID:36010467 -5.4.99.11 * pantoea dispersa 67000.0 3 PMID:15746363;PMID:30290260 -5.4.99.11 * paraburkholderia acidicola 64290.0 5 PMID:16508103;PMID:19783746;PMID:7765505 -5.4.99.11 * pectobacterium carotovorum 68800.0 1 PMID:24411451 -5.4.99.11 * raoultella terrigena 70000.0 1 PMID:19486422;PMID:32910357 -5.4.99.11 * serratia plymuthica 79500.0 3 PMID:16511267 -5.4.99.12 * escherichia coli 31000.0 2 PMID:3276686;PMID:8999885;PMID:9425056 -5.4.99.12 * mus musculus 55552.0 1 PMID:11027153 -5.4.99.13 * cupriavidus metallidurans 135000.0 2 PMID:26134562 -5.4.99.13 * streptomyces virginiae 153000.0 4 PMID:10531377;PMID:9497386 -5.4.99.14 * cupriavidus necator 40000.0 3 PMID:2241929;PMID:9461415 -5.4.99.14 * rhodococcus rhodochrous 75500.0 2 PMID:2818569 -5.4.99.15 * anabaena sp. 114000.0 1 PMID:18322734 -5.4.99.15 * arthrobacter sp. 81000.0 1 PMID:8611744 -5.4.99.15 * metallosphaera hakonensis 150000.0 3 PMID:18051363;PMID:18852510 -5.4.99.15 * nostoc flagelliforme 125000.0 3 PMID:20372031;PMID:21876373 -5.4.99.15 * saccharolobus shibatae 80000.0 2 PMID:12548879;PMID:9063973;PMID:9827330 -5.4.99.15 * saccharolobus solfataricus 87000.0 4 PMID:15150700;PMID:18594890;PMID:8901122 -5.4.99.15 * sulfolobus acidocaldarius 74000.0 1 PMID:12548879;PMID:9063973 -5.4.99.16 * acidiplasma sp. mba-1 65900.0 1 * -5.4.99.16 * corynebacterium glutamicum 70000.0 2 PMID:29460000 -5.4.99.16 * deinococcus geothermalis 132300.0 5 PMID:29460000 -5.4.99.16 * deinococcus radiodurans 126900.0 10 PMID:17394343;PMID:23032750;PMID:29460000 -5.4.99.16 * enterobacter hormaechei 65000.0 3 PMID:19523196;PMID:29460000 -5.4.99.16 * meiothermus ruber 110000.0 1 PMID:19779856 -5.4.99.16 * mycobacterium tuberculosis 390000.0 3 PMID:18505459 -5.4.99.16 * mycolicibacterium smegmatis 390000.0 6 PMID:18505459;PMID:21840994;PMID:23735230 -5.4.99.16 * myxococcus sp. v11 65000.0 2 PMID:33675938 -5.4.99.16 * paenarthrobacter aurescens 68000.0 1 PMID:19172263 -5.4.99.16 * picrophilus oshimae 65000.0 2 PMID:16968068;PMID:29460000 -5.4.99.16 * pseudarthrobacter chlorophenolicus 274000.0 2 PMID:30218299 -5.4.99.16 * pseudomonas monteilii 76720.0 2 PMID:34409951 -5.4.99.16 * pseudomonas putida 75000.0 1 PMID:24563286 -5.4.99.16 * pseudomonas sp. 250000.0 2 * -5.4.99.16 * pseudomonas sp. p8005 126000.0 1 PMID:29460000 -5.4.99.16 * rhodococcus opacus 79000.0 1 PMID:29460000 -5.4.99.16 * stutzerimonas stutzeri 76000.0 2 PMID:29460000 -5.4.99.16 * thermobaculum terrenum 65000.0 1 PMID:29460000 -5.4.99.16 * thermobifida fusca 66000.0 2 PMID:29460000 -5.4.99.16 * thermomonospora curvata 69000.0 3 PMID:29460000;PMID:33285196 -5.4.99.16 * thermus antranikianii 112000.0 1 PMID:31711928 -5.4.99.16 * thermus aquaticus 110000.0 2 PMID:9042362 -5.4.99.16 * thermus thermophilus 164000.0 3 PMID:17256953;PMID:29460000 -5.4.99.16 * uncultured bacterium 63300.0 1 PMID:24146994 -5.4.99.17 * alicyclobacillus acidocaldarius 150000.0 6 PMID:21531832;PMID:2253626;PMID:31588405;PMID:8954152;PMID:9558334 -5.4.99.17 * bradyrhizobium japonicum 76300.0 2 PMID:21531832 -5.4.99.17 * ectopseudomonas mendocina 75000.0 1 PMID:31588405 -5.4.99.17 * kitasatospora albolonga 75000.0 1 PMID:32478051 -5.4.99.17 * methylococcus capsulatus 74100.0 2 PMID:21531832;PMID:9555026 -5.4.99.17 * rhodopseudomonas palustris 72300.0 2 PMID:21531832;PMID:8305486 -5.4.99.17 * streptomyces peucetius 92000.0 2 PMID:19116691;PMID:21531832 -5.4.99.17 * tetrahymena thermophila 72000.0 1 PMID:21531832 -5.4.99.17 * zymomonas mobilis 74100.0 1 PMID:21531832 -5.4.99.18 * acetobacter aceti 197000.0 4 PMID:16819818 -5.4.99.18 * bacillus anthracis 149000.0 1 PMID:25737087 -5.4.99.18 * escherichia coli 136000.0 3 PMID:1534690 -5.4.99.19 * escherichia coli 25836.0 1 PMID:7612632 -5.4.99.2 * escherichia coli 160000.0 4 PMID:18950999 -5.4.99.2 * euglena gracilis 149000.0 3 PMID:20379701 -5.4.99.2 * homo sapiens 150000.0 7 PMID:15259;PMID:21138732;PMID:2907367;PMID:6102092;PMID:6124211 -5.4.99.2 * metallosphaera sedula 70000.0 2 PMID:22752162 -5.4.99.2 * methylorubrum extorquens 78000.0 2 PMID:14734568 -5.4.99.2 * oryctolagus cuniculus 150000.0 1 PMID:15259;PMID:6124211 -5.4.99.2 * ovis aries 165000.0 1 * -5.4.99.2 * propionibacterium freudenreichii subsp. shermanii 165000.0 8 PMID:2569861;PMID:2875711;PMID:4838682 -5.4.99.2 * rattus norvegicus 79000.0 1 PMID:19699272 -5.4.99.2 * saccharopolyspora erythraea 63000.0 1 PMID:6143534 -5.4.99.2 * sinorhizobium meliloti 165000.0 2 PMID:12844209 -5.4.99.20 * escherichia coli 24900.0 1 PMID:17320904 -5.4.99.23 * escherichia coli 44000.0 1 PMID:11087118 -5.4.99.25 * escherichia coli 41500.0 2 PMID:7489483 -5.4.99.27 * escherichia coli 39100.0 1 PMID:12756329 -5.4.99.28 * escherichia coli 24432.0 1 PMID:7493321 -5.4.99.29 * escherichia coli 24432.0 1 PMID:7493321 -5.4.99.30 * arabidopsis thaliana 41300.0 3 PMID:21478444 -5.4.99.30 * oryza sativa 460000.0 8 PMID:17182701;PMID:20057139 -5.4.99.32 * aspergillus fumigatus 83090.0 1 PMID:19951700 -5.4.99.35 * taraxacum coreanum 88090.0 1 PMID:31020326 -5.4.99.39 * betula platyphylla 57290.0 1 PMID:32234222 -5.4.99.39 * bupleurum chinense 87000.0 1 PMID:36160316 -5.4.99.39 * euphorbia tirucalli 77000.0 1 PMID:23294602 -5.4.99.39 * glycine max 84000.0 1 * -5.4.99.39 * glycyrrhiza glabra 87500.0 1 PMID:11510484;PMID:17172290 -5.4.99.39 * gypsophila vaccaria 87500.0 1 PMID:11510484;PMID:17172290 -5.4.99.39 * ocimum basilicum 87000.0 1 PMID:24367017 -5.4.99.39 * panax ginseng 88000.0 1 PMID:9746369 -5.4.99.39 * polygala tenuifolia 87350.0 1 PMID:24420413 -5.4.99.39 * taraxacum coreanum 87500.0 1 PMID:31020326 -5.4.99.4 * eubacterium barkeri 300000.0 6 PMID:12440902;PMID:2776761;PMID:35589197;PMID:5574401 -5.4.99.40 * bacopa monnieri 87620.0 1 PMID:24431524 -5.4.99.40 * catharanthus roseus 87730.0 1 PMID:22837051 -5.4.99.5 * [brevibacterium] flavum 320000.0 1 PMID:479120 -5.4.99.5 * acinetobacter calcoaceticus 91000.0 2 PMID:3046943 -5.4.99.5 * amborella trichopoda 60000.0 2 PMID:28963347 -5.4.99.5 * arabidopsis thaliana 60000.0 3 PMID:25160622 -5.4.99.5 * archaeoglobus fulgidus 420000.0 3 PMID:19082689 -5.4.99.5 * aspergillus nidulans 65000.0 3 PMID:10428795 -5.4.99.5 * bacillus subtilis 140000.0 3 PMID:2105742;PMID:4962500 -5.4.99.5 * chlamydomonas reinhardtii 61000.0 1 PMID:1122289 -5.4.99.5 * claviceps paspali 59000.0 2 PMID:5443801 -5.4.99.5 * claviceps sp. 60000.0 1 PMID:5443801 -5.4.99.5 * corynebacterium glutamicum 23500.0 3 PMID:19589834 -5.4.99.5 * cupriavidus necator 187000.0 3 PMID:1262315 -5.4.99.5 * escherichia coli 78000.0 6 PMID:3037264;PMID:3298984;PMID:795665;PMID:9665711 -5.4.99.5 * globodera rostochiensis 30110.0 1 PMID:18786575 -5.4.99.5 * heterodera schachtii 27900.0 1 PMID:19236568 -5.4.99.5 * kitasatospora aureofaciens 63000.0 4 PMID:3037265;PMID:4196250;PMID:4211872 -5.4.99.5 * methanocaldococcus jannaschii 29390.0 1 PMID:9665711 -5.4.99.5 * mycobacterium tuberculosis 43400.0 16 PMID:15654876;PMID:15737998;PMID:16511071;PMID:16682771;PMID:17146044;PMID:18727669 -5.4.99.5 * mycolicibacterium smegmatis 17800.0 2 PMID:17965159 -5.4.99.5 * nicotiana sylvestris 65000.0 2 PMID:24254044 -5.4.99.5 * ogataea angusta 70000.0 2 PMID:10894726 -5.4.99.5 * physcomitrium patens 60000.0 2 PMID:28963347 -5.4.99.5 * ruta graveolens 56000.0 2 PMID:4083892 -5.4.99.5 * selaginella moellendorffii 60000.0 1 PMID:28963347 -5.4.99.5 * sorghum bicolor 56000.0 2 PMID:4083892 -5.4.99.5 * streptomyces venezuelae 55000.0 1 PMID:5024635 -5.4.99.5 * thermus thermophilus 47590.0 2 PMID:14727008 -5.4.99.5 * vigna radiata 50000.0 2 * -5.4.99.5 * xanthomonas oryzae 40000.0 3 PMID:20128700 -5.4.99.50 * populus davidiana 87810.0 1 PMID:30145615 -5.4.99.61 * pseudomonas denitrificans (nom. rej.) 22060.0 3 PMID:11470433;PMID:2211521;PMID:7606163 -5.4.99.62 * escherichia coli 229608.0 3 PMID:16731978;PMID:31588591 -5.4.99.63 * cereibacter sphaeroides 153000.0 3 PMID:18819910 -5.4.99.64 * aquincola tertiaricarbonis 63414.0 2 PMID:22433853 -5.4.99.7 * bos taurus 140000.0 2 PMID:14678783 -5.4.99.7 * candida albicans 78000.0 1 PMID:9827705 -5.4.99.7 * homo sapiens 86000.0 2 PMID:14766201 -5.4.99.7 * methylococcus capsulatus 94000.0 4 PMID:17567593;PMID:17928701 -5.4.99.7 * pneumocystis carinii 83000.0 1 PMID:19897737 -5.4.99.7 * rattus norvegicus 78000.0 3 PMID:1429550;PMID:2049810;PMID:9827705 -5.4.99.7 * saccharomyces cerevisiae 83000.0 4 PMID:8134375;PMID:9827705 -5.4.99.7 * sus scrofa 90000.0 2 PMID:3355560;PMID:5257956 -5.4.99.8 * betula platyphylla 85530.0 1 PMID:32234222 -5.4.99.8 * centella asiatica 86300.0 1 * -5.4.99.8 * dictyostelium discoideum 81000.0 1 PMID:10783001 -5.4.99.8 * isodon japonicus 110000.0 2 * -5.4.99.8 * lathyrus oleraceus 100000.0 2 * -5.4.99.8 * withania somnifera 113000.0 2 PMID:24770414 -5.4.99.9 * aspergillus fumigatus 275000.0 5 PMID:20615386;PMID:22684076 -5.4.99.9 * escherichia coli 72000.0 3 * -5.4.99.9 * klebsiella pneumoniae 92000.0 2 PMID:9020123 -5.4.99.9 * leishmania major 55000.0 2 PMID:21419104 -5.5.1.1 * arthrobacter sp. 280000.0 3 PMID:14769475 -5.5.1.1 * cutaneotrichosporon cutaneum 169000.0 4 PMID:7193457;PMID:8110801 -5.5.1.1 * frateuria sp. 400000.0 2 PMID:9692194 -5.5.1.1 * pseudomonas putida 260000.0 4 PMID:2280697;PMID:3609743;PMID:4449126 -5.5.1.1 * pseudomonas reinekei 350000.0 4 PMID:17172348;PMID:19465655 -5.5.1.1 * pseudomonas sp. 42000.0 2 PMID:17172348 -5.5.1.1 * rhodococcus erythropolis 400000.0 3 PMID:7751292;PMID:9692194 -5.5.1.1 * rhodococcus rhodochrous 236000.0 2 PMID:12855164 -5.5.1.10 * nocardia sp. 50000.0 3 PMID:3667522 -5.5.1.11 * cupriavidus necator 270000.0 2 PMID:2327971 -5.5.1.12 * abies grandis 90000.0 2 PMID:11552804;PMID:8053674 -5.5.1.12 * pinus contorta 80000.0 1 PMID:8053674 -5.5.1.13 * fusarium fujikuroi 107000.0 1 PMID:10803977 -5.5.1.13 * lathyrus oleraceus 92000.0 1 PMID:9107034 -5.5.1.13 * marah macrocarpa 83000.0 2 PMID:16662063 -5.5.1.13 * oryza sativa 84900.0 2 PMID:18256497 -5.5.1.13 * physcomitrium patens 106000.0 2 PMID:17064690 -5.5.1.15 * kitasatospora griseola 50000.0 1 PMID:12138123 -5.5.1.18 * chromochloris zofingiensis 71100.0 1 PMID:23118722 -5.5.1.18 * ipomoea batatas 47000.0 1 * -5.5.1.19 * capsicum annuum 66000.0 1 PMID:20460582 -5.5.1.19 * ficus carica 56000.0 1 PMID:21792589 -5.5.1.19 * lycium chinense 56600.0 1 * -5.5.1.19 * paracoccus haeundaensis 43000.0 1 PMID:23412054 -5.5.1.19 * rhodotorula diobovata 65630.0 1 PMID:24677129 -5.5.1.19 * synechococcus elongatus 46125.0 1 PMID:7919981 -5.5.1.2 * agrobacterium tumefaciens 42000.0 2 PMID:17054713;PMID:17074892 -5.5.1.2 * aspergillus niger 191000.0 1 PMID:5076660 -5.5.1.2 * pseudomonas aeruginosa 40000.0 1 PMID:18832304 -5.5.1.2 * pseudomonas putida 190000.0 2 PMID:4199895;PMID:5916392 -5.5.1.20 * alternaria solani 60000.0 2 PMID:18256508;PMID:9659400 -5.5.1.22 * tanacetum vulgare 65000.0 1 PMID:2178556 -5.5.1.23 * streptomyces peucetius 16572.0 2 PMID:10200167 -5.5.1.23 * streptomyces sp. 18495.0 1 PMID:7836284 -5.5.1.24 * eucalyptus gunnii 56700.0 1 * -5.5.1.24 * lactuca sativa 56760.0 1 PMID:21523658 -5.5.1.24 * trichormus variabilis 42000.0 1 PMID:8831985 -5.5.1.26 * streptomyces nogalater 20472.0 2 PMID:15159574 -5.5.1.27 * agrobacterium tumefaciens 340900.0 3 PMID:22493433 -5.5.1.4 * acer pseudoplatanus 150000.0 1 PMID:9370339 -5.5.1.4 * actinidia arguta 56500.0 1 PMID:24184456 -5.5.1.4 * actinidia deliciosa 56500.0 1 PMID:24184456 -5.5.1.4 * actinidia eriantha 56500.0 1 PMID:24184456 -5.5.1.4 * actinidia rufa 56500.0 1 PMID:24184456 -5.5.1.4 * arabidopsis thaliana 56510.0 6 PMID:20215587;PMID:21971746 -5.5.1.4 * archaeoglobus fulgidus 168000.0 2 PMID:11015222 -5.5.1.4 * bos taurus 218000.0 3 PMID:7154962;PMID:7407062;PMID:9370339 -5.5.1.4 * brassica napus 46249.0 1 PMID:9370339 -5.5.1.4 * citrus x paradisi 56337.0 1 PMID:9370339 -5.5.1.4 * cyberlindnera jadinii 105000.0 1 * -5.5.1.4 * drosophila melanogaster 271000.0 2 PMID:15357287 -5.5.1.4 * entamoeba histolytica 56685.0 1 PMID:9370339 -5.5.1.4 * euglena gracilis 248000.0 5 PMID:12223840;PMID:9370339 -5.5.1.4 * hevea brasiliensis 159000.0 1 PMID:9370339 -5.5.1.4 * homo sapiens 170000.0 2 PMID:22707096;PMID:3243558;PMID:9370339 -5.5.1.4 * lemna gibba 135000.0 2 PMID:208949;PMID:9370339 -5.5.1.4 * lilium longiflorum 157000.0 3 PMID:6736020;PMID:9370339 -5.5.1.4 * limnospira platensis 200300.0 3 PMID:12223840;PMID:9370339 -5.5.1.4 * mesembryanthemum crystallinum 56761.0 1 PMID:9370339 -5.5.1.4 * mycobacterium tuberculosis 140000.0 1 PMID:26420670 -5.5.1.4 * neurospora crassa 345000.0 4 PMID:6216853;PMID:9370339 -5.5.1.4 * oryza coarctata 180000.0 4 PMID:15016817;PMID:20213122 -5.5.1.4 * oryza sativa 253000.0 12 PMID:12223840;PMID:15016817;PMID:20213122;PMID:21971746;PMID:9370339 -5.5.1.4 * phaseolus vulgaris 56529.0 1 PMID:9370339 -5.5.1.4 * pinus ponderosa 155000.0 1 PMID:9370339 -5.5.1.4 * rattus norvegicus 290000.0 10 PMID:19188364;PMID:3243558;PMID:4352864;PMID:4372945;PMID:4373376;PMID:6773943;PMID:9370339 -5.5.1.4 * saccharomyces cerevisiae 240000.0 4 PMID:2642902;PMID:7016881;PMID:9370339 -5.5.1.4 * spirodela polyrhiza 56388.0 1 PMID:9370339 -5.5.1.4 * streptomyces sp. 260000.0 2 PMID:2515106;PMID:9370339 -5.5.1.4 * synechocystis sp. 200000.0 8 PMID:14730448;PMID:16453101 -5.5.1.4 * triticum aestivum 56300.0 2 PMID:21971746 -5.5.1.4 * vigna radiata 266000.0 3 PMID:12223840;PMID:9370339 -5.5.1.4 * xerophyta viscosa 56690.0 1 * -5.5.1.5 * aspergillus niger 200000.0 3 PMID:4448182;PMID:4448183 -5.5.1.5 * neurospora crassa 158000.0 3 PMID:8132467 -5.5.1.6 * citrus sinensis 27800.0 2 * -5.5.1.6 * eubacterium ramulus 270000.0 6 PMID:15127184;PMID:24459060;PMID:25849401;PMID:27551015 -5.5.1.6 * ginkgo biloba 26290.0 1 PMID:21046109 -5.5.1.6 * glycine max 24000.0 2 PMID:11698411;PMID:236184;PMID:3384815 -5.5.1.6 * medicago sativa 24000.0 1 PMID:11698411;PMID:3384815 -5.5.1.6 * petunia x hybrida 62500.0 4 PMID:24258172;PMID:3631964 -5.5.1.6 * phaseolus vulgaris 30000.0 3 PMID:3631964;PMID:6489352 -5.5.1.6 * pongamia pinnata 23640.0 1 PMID:23615469 -5.5.1.6 * saussurea medusa 24000.0 1 PMID:17010632 -5.5.1.7 * escherichia coli 39000.0 1 PMID:7751312 -5.5.1.7 * pseudomonas sp. 39780.0 1 PMID:3360749 -5.5.1.7 * rhodococcus erythropolis 250000.0 1 PMID:7751292 -5.5.1.8 * salvia officinalis 95000.0 1 PMID:42356 -5.6.1.1 * arabidopsis thaliana 85000.0 10 PMID:12020351;PMID:16805733;PMID:17977001 -5.6.1.1 * caenorhabditis elegans 80000.0 5 PMID:17084690;PMID:17531954;PMID:19619244 -5.6.1.1 * chlamydomonas reinhardtii 84000.0 7 PMID:10209026;PMID:10401578;PMID:10910766;PMID:15302820;PMID:9568719;PMID:9571249;PMID:9658175 -5.6.1.1 * homo sapiens 530000.0 16 PMID:15716377;PMID:16219033;PMID:17348041;PMID:17389232;PMID:18410514;PMID:18613979;PMID:9571249 -5.6.1.1 * oryza sativa 60000.0 1 PMID:16040652 -5.6.1.1 * rattus norvegicus 80000.0 6 PMID:10209026;PMID:10401578;PMID:10910766;PMID:15215300;PMID:18305248;PMID:24303010;PMID:9568719;PMID:9658175 -5.6.1.1 * strongylocentrotus purpuratus 81000.0 4 PMID:10209026;PMID:10401578;PMID:10910766;PMID:8221885;PMID:9568719;PMID:9658175 -5.6.1.1 * xenopus laevis 81000.0 2 PMID:8907702 -5.6.1.10 * avena sativa 70000.0 8 PMID:9477575 -5.6.1.10 * bos taurus 78000.0 8 PMID:10086320;PMID:1356434;PMID:17140383;PMID:7547895;PMID:7836457;PMID:7836458;PMID:8509407 -5.6.1.10 * entamoeba histolytica 86000.0 2 PMID:24486610 -5.6.1.10 * escherichia coli 570000.0 6 PMID:10713091;PMID:1979147;PMID:30092228;PMID:9454592 -5.6.1.10 * gallus sp. 184000.0 2 PMID:9933607 -5.6.1.10 * gillichthys mirabilis 70000.0 1 PMID:11533117 -5.6.1.10 * homo sapiens 180000.0 3 PMID:26991466;PMID:7547895;PMID:7836457;PMID:7836458;PMID:8509407;PMID:8742329;PMID:9083109;PMID:9488662 -5.6.1.10 * mycobacterium tuberculosis 560000.0 2 PMID:30338218 -5.6.1.10 * paralichthys olivaceus 70100.0 1 PMID:22898664 -5.6.1.10 * plasmodium falciparum 73500.0 2 PMID:14711509 -5.6.1.10 * pohlia nutans 72820.0 1 * -5.6.1.10 * saccharomyces cerevisiae 611000.0 1 PMID:16135516 -5.6.1.10 * solanum lycopersicum 70000.0 2 PMID:7547895;PMID:7836457;PMID:7836458;PMID:8509407;PMID:8742329;PMID:9083109;PMID:9488662 -5.6.1.10 * zea mays 70000.0 2 PMID:7547895;PMID:7836457;PMID:7836458;PMID:8509407;PMID:8742329;PMID:9083109;PMID:9488662 -5.6.1.2 * bos taurus 420000.0 5 PMID:2950294 -5.6.1.2 * chlamydomonas reinhardtii 1250000.0 10 PMID:3029544;PMID:6220019 -5.6.1.2 * dictyostelium discoideum 380000.0 1 PMID:22863569 -5.6.1.2 * hemicentrotus pulcherrimus 550000.0 1 PMID:2950296 -5.6.1.2 * mytilus edulis 450000.0 12 PMID:1487508 -5.6.1.2 * neurospora crassa 1500000.0 1 PMID:10863006 -5.6.1.2 * saccharomyces cerevisiae 331000.0 1 PMID:34015309 -5.6.1.2 * schizosaccharomyces pombe 540000.0 1 PMID:32694211 -5.6.1.2 * spisula solidissima 450000.0 12 PMID:1487508 -5.6.1.2 * strongylocentrotus droebachiensis 385000.0 3 PMID:2950295 -5.6.1.2 * strongylocentrotus purpuratus 385000.0 3 PMID:2950295 -5.6.1.2 * tetrahymena thermophila 2000000.0 2 PMID:2950293;PMID:6220019 -5.6.1.2 * tripneustes gratilla 1250000.0 7 * -5.6.1.3 * bos taurus 120000.0 1 PMID:3926325 -5.6.1.3 * dictyostelium discoideum 480000.0 10 PMID:10545495;PMID:18160177 -5.6.1.3 * doryteuthis pealeii 600000.0 3 PMID:3115997;PMID:3926325 -5.6.1.3 * drosophila melanogaster 520000.0 2 PMID:18702529;PMID:19062285 -5.6.1.3 * drosophila sp. (in: flies) 90000.0 2 PMID:8780525 -5.6.1.3 * homo sapiens 124000.0 7 PMID:10617199;PMID:15247293;PMID:7744954;PMID:7844144 -5.6.1.3 * mus musculus 350000.0 6 PMID:7559760 -5.6.1.3 * neurospora crassa 49500.0 1 PMID:18205396 -5.6.1.3 * schizosaccharomyces pombe 184000.0 2 PMID:19037096 -5.6.1.4 * caenorhabditis elegans 94000.0 2 PMID:15850386 -5.6.1.4 * drosophila melanogaster 80000.0 3 PMID:7849016;PMID:8780525 -5.6.1.4 * gossypium hirsutum 120000.0 2 PMID:15557092 -5.6.1.4 * homo sapiens 87400.0 2 PMID:7889940 -5.6.1.4 * mus musculus 74000.0 1 PMID:9105041 -5.6.1.4 * neurospora crassa 105000.0 1 PMID:9288974 -5.6.1.4 * rattus norvegicus 74000.0 1 PMID:9105041 -5.6.1.4 * saccharomyces cerevisiae 88880.0 5 PMID:16107877;PMID:22977241;PMID:8041770;PMID:8780525 -5.6.1.4 * schizosaccharomyces pombe 182000.0 1 PMID:19430466 -5.6.1.4 * xenopus laevis 90000.0 1 PMID:10359605 -5.6.1.5 * haloferax volcanii 45664.0 2 PMID:15516591 -5.6.1.5 * homo sapiens 51550.0 5 PMID:7729537 -5.6.1.5 * manduca sexta 47000.0 1 PMID:9009228 -5.6.1.5 * methanocaldococcus jannaschii 700000.0 3 PMID:10473546;PMID:10692374 -5.6.1.5 * mycobacterium tuberculosis 100000.0 3 PMID:19836337 -5.6.1.5 * plasmodium falciparum 2000000.0 2 PMID:10529354;PMID:9688553 -5.6.1.5 * rattus norvegicus 2000000.0 3 PMID:10529354;PMID:9228289;PMID:9688553 -5.6.1.5 * saccharomyces cerevisiae 700000.0 9 PMID:10529354;PMID:17329811;PMID:7729537;PMID:9228289;PMID:9688553 -5.6.1.5 * thermoplasma sp. 2000000.0 3 PMID:10529354;PMID:9228289;PMID:9688553 -5.6.1.6 * homo sapiens 212000.0 6 PMID:11524016;PMID:16504487;PMID:19386787;PMID:27913277 -5.6.1.6 * mus musculus 160000.0 1 PMID:22711960 -5.6.1.6 * trichosurus vulpecula 168200.0 1 PMID:20012660 -5.6.1.7 * acetivibrio thermocellus 450000.0 2 PMID:7912671;PMID:8687408 -5.6.1.7 * aeropyrum pernix 60000.0 1 PMID:17092293 -5.6.1.7 * amoeba proteus 800000.0 2 PMID:11722184 -5.6.1.7 * cereibacter sphaeroides 889200.0 2 PMID:1678280 -5.6.1.7 * escherichia coli 812000.0 11 PMID:11342042;PMID:16672234;PMID:17178727;PMID:18261461;PMID:18418386;PMID:22273181;PMID:23183375;PMID:9657960 -5.6.1.7 * haloferax volcanii 95400.0 3 PMID:12482584 -5.6.1.7 * homo sapiens 960000.0 2 PMID:7601114 -5.6.1.7 * lathyrus oleraceus 60000.0 1 PMID:2577724 -5.6.1.7 * methanococcus maripaludis 900000.0 1 PMID:12628000 -5.6.1.7 * mycoplasmoides gallisepticum 62000.0 1 PMID:25304689 -5.6.1.7 * ochlerotatus triseriatus 57179.0 1 PMID:11762197 -5.6.1.7 * pseudomonas phage el 863000.0 2 PMID:32339190 -5.6.1.7 * pseudomonas phage obp 420000.0 1 PMID:27247423 -5.6.1.7 * pyrococcus furiosus 66200.0 2 PMID:17440915;PMID:19298788 -5.6.1.7 * pyrococcus horikoshii 10000000.0 1 PMID:30255156 -5.6.1.7 * saccharolobus solfataricus 920000.0 4 PMID:7833806;PMID:7932699 -5.6.1.7 * sulfurisphaera tokodaii 56000.0 2 PMID:9245723 -5.6.1.7 * thermoanaerobacter brockii 450000.0 3 PMID:7912671;PMID:8687408 -5.6.1.8 * acanthamoeba castellanii 400000.0 11 PMID:6126796 -5.6.1.8 * bos taurus 20000.0 2 PMID:3160691 -5.6.1.8 * canis lupus familiaris 225000.0 1 * -5.6.1.9 * acidaminococcus fermentans 60000.0 2 PMID:3691501;PMID:7607244 -5.6.1.9 * clostridioides difficile 72000.0 1 PMID:22827463 -5.6.2.1 * acanthamoeba polyphaga mimivirus 37000.0 1 PMID:16352556 -5.6.2.1 * artemia franciscana 63000.0 1 PMID:1311554 -5.6.2.1 * bacillus cereus 82000.0 1 PMID:16556226 -5.6.2.1 * bos taurus 145000.0 2 PMID:2825774 -5.6.2.1 * brassica oleracea 80000.0 1 PMID:1316191 -5.6.2.1 * crithidia fasciculata 79000.0 1 PMID:3041212 -5.6.2.1 * desulfurococcus amylolyticus 108000.0 1 PMID:1648092 -5.6.2.1 * drosophila sp. (in: flies) 135000.0 1 PMID:6294622 -5.6.2.1 * escherichia coli 168000.0 9 PMID:16582104;PMID:16684778;PMID:2559654;PMID:2986908;PMID:6267993 -5.6.2.1 * gallus gallus 100000.0 4 PMID:6280758;PMID:6303401 -5.6.2.1 * geobacillus stearothermophilus 150000.0 4 PMID:2991208 -5.6.2.1 * homo sapiens 200000.0 5 PMID:16757380;PMID:16819839;PMID:18826252;PMID:2559076 -5.6.2.1 * leishmania donovani 102000.0 12 PMID:15135057;PMID:16757380;PMID:17222179;PMID:17900785 -5.6.2.1 * leishmania sp. 73000.0 14 PMID:17924857 -5.6.2.1 * lentinula edodes 235000.0 2 * -5.6.2.1 * mammalia 91000.0 1 PMID:16757380 -5.6.2.1 * micrococcus luteus 120000.0 1 PMID:2986908 -5.6.2.1 * mus musculus 102000.0 2 PMID:6313674 -5.6.2.1 * mycobacterium tuberculosis 100000.0 2 PMID:30087665;PMID:8921893 -5.6.2.1 * nicotiana tabacum 30000.0 1 PMID:16667754 -5.6.2.1 * orthopoxvirus vaccinia 33000.0 4 PMID:2823264;PMID:2846543;PMID:3036853 -5.6.2.1 * oryza sativa 80000.0 1 PMID:2018760 -5.6.2.1 * plasmodium falciparum 104000.0 1 PMID:16757380 -5.6.2.1 * saccharomyces cerevisiae 98000.0 3 PMID:6088500;PMID:6296118 -5.6.2.1 * trypanosoma brucei 90000.0 2 PMID:15478803 -5.6.2.1 * trypanosoma cruzi 65000.0 1 PMID:6309514 -5.6.2.1 * variola virus 32000.0 1 PMID:17035663 -5.6.2.1 * xenopus laevis 70000.0 1 PMID:2986908 -5.6.2.2 * bos taurus 300000.0 7 PMID:14519130;PMID:2982821;PMID:3023077 -5.6.2.2 * cricetulus griseus 170000.0 1 PMID:2550059 -5.6.2.2 * crithidia fasciculata 264000.0 2 PMID:2536375 -5.6.2.2 * daucus carota 123000.0 2 * -5.6.2.2 * desulfurococcus amylolyticus 135000.0 1 PMID:2834207 -5.6.2.2 * drosophila melanogaster 261000.0 2 PMID:6308010 -5.6.2.2 * escherichia coli 400000.0 5 PMID:2559654;PMID:2986908 -5.6.2.2 * homo sapiens 183000.0 8 PMID:16271071;PMID:18417590;PMID:18820297;PMID:23088786;PMID:31096154;PMID:7797575 -5.6.2.2 * leishmania donovani 43000.0 1 PMID:15901238 -5.6.2.2 * methanopyrus kandleri 138000.0 2 PMID:9153263 -5.6.2.2 * methanosarcina mazei 68760.0 3 PMID:17603498 -5.6.2.2 * micrococcus luteus 115000.0 4 PMID:2986908;PMID:6267993 -5.6.2.2 * pyrococcus furiosus 120000.0 1 PMID:9045834 -5.6.2.2 * rattus norvegicus 173000.0 3 PMID:8038715;PMID:8765751 -5.6.2.2 * saccharolobus shibatae 230000.0 9 PMID:11485995;PMID:18334211;PMID:7961685;PMID:9801313 -5.6.2.2 * saccharolobus solfataricus 145700.0 2 PMID:25200003 -5.6.2.2 * saccharomyces cerevisiae 265000.0 3 PMID:6088500;PMID:7893659 -5.6.2.2 * staphylococcus aureus 59000.0 2 PMID:17077506 -5.6.2.2 * sulfolobus acidocaldarius 13200.0 1 PMID:14708549 -5.6.2.2 * sulfolobus sp. 85000.0 2 PMID:8086447 -5.6.2.2 * tequatrovirus t4 57000.0 3 PMID:6312256 -5.6.2.2 * trypanosoma cruzi 200000.0 1 PMID:3020537 -5.6.2.2 * xenopus laevis 175000.0 1 PMID:10872324 -5.6.2.3 * arabidopsis thaliana 80000.0 2 PMID:23452619 -5.6.2.3 * bacillus anthracis 50000.0 1 PMID:18931108 -5.6.2.3 * bos taurus 57000.0 1 PMID:1313298 -5.6.2.3 * drosophila melanogaster 200000.0 2 PMID:7501468;PMID:8631322 -5.6.2.3 * fromanvirus d29 318000.0 2 PMID:26237048 -5.6.2.3 * helicobacter pylori 360000.0 1 PMID:14627816 -5.6.2.3 * homo sapiens 600000.0 6 PMID:11292846;PMID:12917423;PMID:12975372;PMID:18835853;PMID:20659899;PMID:26615986 -5.6.2.3 * plasmodium falciparum 59000.0 1 PMID:23219504 -5.6.2.3 * pyrococcus horikoshii 137000.0 1 PMID:12473672 -5.6.2.3 * saccharomyces cerevisiae 500000.0 4 PMID:8387501;PMID:8408033;PMID:9341218 -5.6.2.3 * schizosaccharomyces pombe 65000.0 2 PMID:9716495 -5.6.2.3 * severe acute respiratory syndrome-related coronavirus 70000.0 1 PMID:12917423;PMID:12975372 -5.6.2.4 * drosophila melanogaster 54000.0 1 PMID:11452023 -5.6.2.4 * escherichia coli 82000.0 1 PMID:34235303 -5.6.2.4 * homo sapiens 142000.0 2 PMID:15202501;PMID:7543199 -5.6.2.4 * lathyrus oleraceus 560000.0 7 PMID:12694186;PMID:21336027;PMID:8665952 -5.6.2.4 * leishmania donovani 152000.0 1 PMID:34355508 -5.6.2.4 * mycobacterium tuberculosis 85000.0 1 PMID:17158674 -5.6.2.4 * plasmodium falciparum 170000.0 3 PMID:16772048;PMID:18242886;PMID:25111966 -5.6.2.4 * saccharolobus solfataricus 470000.0 8 PMID:11821426;PMID:17683280;PMID:19073923 -5.6.2.5 * homo sapiens 130000.0 1 PMID:10999600 -5.6.2.6 * homo sapiens 246000.0 5 PMID:1537828;PMID:16914450;PMID:20659012;PMID:8407977;PMID:9547260 -5.6.2.6 * japanese encephalitis virus 54000.0 1 PMID:18201743 -5.6.2.6 * kokobera virus 49800.0 1 PMID:17329812 -5.6.2.6 * tenuivirus oryzalbae 109000.0 2 PMID:19218918 -5.6.2.6 * west nile virus 66000.0 1 PMID:18448185 -5.99.1.4 * brevundimonas vesicularis 24700.0 1 * -5.99.1.4 * comamonas testosteroni 24700.0 1 * -5.99.1.4 * pseudomonas putida 23031.0 1 PMID:8002605 -5.99.1.4 * pseudomonas sp. 27000.0 2 PMID:9722670 -6.1.1.1 * acanthamoeba polyphaga mimivirus 84134.0 1 PMID:23384724 -6.1.1.1 * acidithiobacillus ferrooxidans 105000.0 3 PMID:11240138;PMID:7517395 -6.1.1.1 * bos taurus 43000.0 1 PMID:18165356 -6.1.1.1 * drosophila melanogaster 100000.0 1 PMID:821600 -6.1.1.1 * escherichia coli 97000.0 3 PMID:4576576 -6.1.1.1 * geobacillus stearothermophilus 95000.0 1 PMID:4831635 -6.1.1.1 * homo sapiens 130000.0 3 PMID:12509991;PMID:15779907 -6.1.1.1 * lathyrus oleraceus 70000.0 2 PMID:4563531 -6.1.1.1 * plasmodium falciparum 118000.0 1 PMID:30592748 -6.1.1.1 * rattus norvegicus 120000.0 2 PMID:593893 -6.1.1.1 * saccharomyces cerevisiae 46500.0 3 PMID:328277;PMID:4558241 -6.1.1.1 * triticum aestivum 110000.0 2 PMID:3170582 -6.1.1.10 * arabidopsis thaliana 62000.0 1 PMID:9724821 -6.1.1.10 * escherichia coli 85000.0 3 PMID:2126467;PMID:4605346;PMID:6094501 -6.1.1.10 * geobacillus stearothermophilus 149000.0 1 PMID:11233169 -6.1.1.10 * homo sapiens 100000.0 2 PMID:15274629;PMID:24103465 -6.1.1.10 * lupinus sp. 170000.0 2 * -6.1.1.10 * mycolicibacterium smegmatis 85000.0 6 PMID:19478446;PMID:971320 -6.1.1.10 * oryza sativa 110000.0 4 PMID:11118226 -6.1.1.10 * ovis aries 78000.0 1 PMID:566665 -6.1.1.10 * pyrococcus abyssi 84000.0 3 PMID:12390027 -6.1.1.10 * saccharomyces cerevisiae 80000.0 1 PMID:3905796 -6.1.1.10 * thermus thermophilus 175000.0 2 PMID:6468656 -6.1.1.10 * triticum aestivum 165000.0 8 PMID:1157945;PMID:6164366;PMID:913394 -6.1.1.10 * vigna radiata var. radiata 340000.0 2 PMID:16661668 -6.1.1.10 * xanthomonas citri 280000.0 1 PMID:33857480 -6.1.1.11 * bombyx mori 124000.0 2 PMID:2826448 -6.1.1.11 * bos taurus 170000.0 6 PMID:10764807;PMID:11577083;PMID:6565588 -6.1.1.11 * escherichia coli 103000.0 4 PMID:4350948;PMID:4906848 -6.1.1.11 * geobacillus stearothermophilus 88000.0 3 PMID:690138 -6.1.1.11 * homo sapiens 154000.0 1 PMID:26433229 -6.1.1.11 * lupinus luteus 110000.0 2 PMID:240681 -6.1.1.11 * saccharomyces cerevisiae 114000.0 3 PMID:7686490 -6.1.1.11 * zea mays 59000.0 2 PMID:18392626;PMID:9747857 -6.1.1.12 * bos taurus 117000.0 1 PMID:6849897 -6.1.1.12 * escherichia coli 132000.0 5 PMID:10873442;PMID:33736288;PMID:342244 -6.1.1.12 * helicobacter pylori 15500.0 2 PMID:23454362 -6.1.1.12 * homo sapiens 50000.0 1 PMID:19443655 -6.1.1.12 * leishmania donovani 132000.0 1 PMID:33736288;PMID:342244 -6.1.1.12 * plasmodium falciparum 66000.0 1 PMID:19443655 -6.1.1.12 * saccharomyces cerevisiae 260000.0 8 PMID:19443655;PMID:4570972;PMID:6362667 -6.1.1.12 * sus scrofa 500000.0 5 PMID:6863285;PMID:7285922 -6.1.1.12 * thermococcus kodakarensis 50893.0 4 PMID:7590306;PMID:8925930 -6.1.1.12 * thermus thermophilus 122000.0 5 PMID:10727213;PMID:11468411;PMID:12351895;PMID:8319804 -6.1.1.12 * trypanosoma brucei 62900.0 2 PMID:19386587 -6.1.1.13 * lacticaseibacillus casei 39000.0 1 PMID:4399593 -6.1.1.14 * arabidopsis thaliana 117000.0 5 PMID:11278923;PMID:9707529 -6.1.1.14 * bombyx mori 270000.0 7 PMID:4044548;PMID:6706990;PMID:8845358 -6.1.1.14 * bos taurus 202000.0 2 PMID:6849897 -6.1.1.14 * brevibacillus brevis 226000.0 4 PMID:1149746 -6.1.1.14 * escherichia coli 240000.0 7 PMID:4594761;PMID:6992865 -6.1.1.14 * homo sapiens 77530.0 1 PMID:7961834 -6.1.1.14 * saccharomyces cerevisiae 250000.0 7 PMID:12855679;PMID:7008831 -6.1.1.14 * thermus thermophilus 51000.0 1 PMID:9490048 -6.1.1.15 * bos taurus 162000.0 2 PMID:6849897 -6.1.1.15 * homo sapiens 172000.0 1 PMID:18374644 -6.1.1.15 * methanocaldococcus jannaschii 105000.0 2 PMID:16226256 -6.1.1.15 * methanothermobacter thermautotrophicus 113000.0 2 PMID:16226256 -6.1.1.15 * rattus norvegicus 133000.0 2 PMID:1517216 -6.1.1.15 * thermus aquaticus 127000.0 2 PMID:6380688 -6.1.1.16 * bos taurus 262000.0 2 PMID:6849897 -6.1.1.16 * escherichia coli 52280.0 2 PMID:10216301;PMID:2014166 -6.1.1.16 * geobacillus stearothermophilus 54000.0 1 PMID:488099 -6.1.1.16 * methanosarcina mazei 42324.0 2 PMID:18559341 -6.1.1.16 * oryctolagus cuniculus 92000.0 2 PMID:9810464 -6.1.1.16 * rattus norvegicus 300000.0 5 PMID:990314 -6.1.1.16 * vigna radiata var. radiata 61000.0 2 PMID:16659657 -6.1.1.17 * arabidopsis thaliana 81000.0 1 PMID:9765600 -6.1.1.17 * babesia bovis 72000.0 1 PMID:22561041 -6.1.1.17 * bacillus subtilis 65500.0 2 PMID:6401718;PMID:9674110 -6.1.1.17 * bos taurus 111000.0 1 PMID:6849897 -6.1.1.17 * chlamydomonas reinhardtii 62000.0 3 PMID:16667668;PMID:2303494 -6.1.1.17 * escherichia coli 102000.0 8 PMID:1384858;PMID:17049867;PMID:2590524;PMID:368055;PMID:369459;PMID:4341531;PMID:4560497 -6.1.1.17 * geobacillus stearothermophilus 55671.0 1 PMID:2120226 -6.1.1.17 * homo sapiens 172000.0 1 PMID:18374644 -6.1.1.17 * plasmodium falciparum 68400.0 2 PMID:24072705 -6.1.1.17 * sinorhizobium meliloti 54000.0 1 PMID:1384858;PMID:2590524 -6.1.1.17 * streptococcus pneumoniae 58000.0 1 PMID:17703427 -6.1.1.17 * tetradesmus obliquus 105000.0 2 * -6.1.1.17 * thermus thermophilus 53901.0 1 PMID:1541262 -6.1.1.17 * triticum aestivum 165000.0 6 PMID:6617644 -6.1.1.18 * bos taurus 138000.0 1 PMID:6849897 -6.1.1.18 * escherichia coli 71200.0 6 PMID:17049867;PMID:21397189;PMID:6749844;PMID:6989402 -6.1.1.18 * saccharomyces cerevisiae 93100.0 3 PMID:23583912;PMID:8449914 -6.1.1.19 * canavalia ensiformis 67400.0 1 PMID:19187230 -6.1.1.19 * caryedes brasiliensis 76700.0 2 PMID:24446543 -6.1.1.19 * escherichia coli 68000.0 3 PMID:17061034;PMID:37899;PMID:7076660 -6.1.1.19 * geobacillus stearothermophilus 78000.0 4 PMID:1253985;PMID:13678419;PMID:7358046 -6.1.1.19 * glycine max 68200.0 1 PMID:19187230 -6.1.1.19 * homo sapiens 75000.0 1 PMID:16430231 -6.1.1.19 * mycolicibacterium smegmatis 58000.0 2 PMID:179818;PMID:3782054 -6.1.1.19 * plasmodium falciparum 69000.0 1 PMID:27502052 -6.1.1.19 * rattus norvegicus 240000.0 5 PMID:1953742;PMID:37899;PMID:465071;PMID:7076660 -6.1.1.19 * saccharomyces cerevisiae 69500.0 1 PMID:9736621 -6.1.1.19 * saccharomyces pastorianus 80000.0 6 PMID:179818;PMID:3782054;PMID:6337851 -6.1.1.19 * triticum aestivum 73000.0 2 PMID:679950 -6.1.1.2 * bos taurus 120000.0 6 PMID:804406 -6.1.1.2 * homo sapiens 53000.0 4 PMID:10828066;PMID:19900940;PMID:19913117 -6.1.1.2 * lupinus luteus 200000.0 2 PMID:240681 -6.1.1.2 * plasmodium falciparum 140000.0 2 PMID:23776638 -6.1.1.20 * bombyx mori 62000.0 2 * -6.1.1.20 * bos taurus 260000.0 3 PMID:2205792 -6.1.1.20 * chlorobium limicola 260000.0 1 PMID:10575359;PMID:3081498;PMID:6724523 -6.1.1.20 * cyanophora paradoxa 260000.0 1 PMID:10575359;PMID:3081498;PMID:6724523 -6.1.1.20 * escherichia coli 267000.0 7 PMID:4598754;PMID:6360212 -6.1.1.20 * gallus gallus 255000.0 3 PMID:7103994 -6.1.1.20 * glycine max 80000.0 1 * -6.1.1.20 * homo sapiens 297000.0 23 PMID:10049785;PMID:10329163;PMID:11858721;PMID:17768348;PMID:18611382;PMID:18662515;PMID:19193993;PMID:19737557;PMID:20223217;PMID:2207203;PMID:6373755 -6.1.1.20 * methanobacterium thermoautotrophicus 260000.0 3 PMID:10575359;PMID:3081498;PMID:6724523 -6.1.1.20 * methanosarcina barkeri 270000.0 3 PMID:2207203;PMID:6373755 -6.1.1.20 * phaseolus vulgaris 260000.0 6 PMID:10575359;PMID:3081498;PMID:6724523 -6.1.1.20 * saccharolobus solfataricus 240000.0 3 PMID:12007606 -6.1.1.20 * saccharomyces cerevisiae 350000.0 4 PMID:6992780;PMID:766925 -6.1.1.20 * staphylococcus aureus 90000.0 3 PMID:11281723 -6.1.1.20 * sulfolobus acidocaldarius 270000.0 1 PMID:2207203;PMID:6373755 -6.1.1.20 * synechococcus elongatus pcc 7942 = fachb-805 260000.0 1 PMID:10575359;PMID:3081498;PMID:6724523 -6.1.1.20 * thermococcus kodakarensis 66200.0 2 PMID:14607984 -6.1.1.20 * thermus thermophilus 245000.0 3 * -6.1.1.21 * bos taurus 160000.0 4 PMID:3620106;PMID:6849897 -6.1.1.21 * caulobacter vibrioides 52300.0 1 PMID:21087993 -6.1.1.21 * escherichia coli 85000.0 4 PMID:10430027;PMID:4591623 -6.1.1.21 * homo sapiens 120000.0 3 PMID:10430027 -6.1.1.21 * methanocaldococcus jannaschii 48300.0 1 PMID:10430027 -6.1.1.21 * mus musculus 57400.0 1 PMID:10430027 -6.1.1.21 * mycobacterium leprae 48800.0 1 PMID:10430027 -6.1.1.21 * mycobacterium tuberculosis 41100.0 1 PMID:10430027 -6.1.1.21 * mycoplasmoides genitalium 48300.0 1 PMID:10430027 -6.1.1.21 * mycoplasmoides pneumoniae 47300.0 1 PMID:10430027 -6.1.1.21 * neurospora crassa 125000.0 2 PMID:6449959 -6.1.1.21 * oryctolagus cuniculus 122000.0 2 PMID:246747;PMID:6712685 -6.1.1.21 * oryza sativa 55300.0 1 PMID:10430027 -6.1.1.21 * porphyra purpurea 49800.0 1 PMID:10430027 -6.1.1.21 * rattus norvegicus 115000.0 4 PMID:246747;PMID:3499936;PMID:6712685 -6.1.1.21 * saccharomyces cerevisiae 60000.0 1 PMID:10430027 -6.1.1.21 * salmonella enterica subsp. enterica serovar typhimurium 92000.0 4 PMID:10430027;PMID:4590693 -6.1.1.21 * streptococcus dysgalactiae subsp. equisimilis 108200.0 5 PMID:10430027;PMID:8441673 -6.1.1.21 * synechococcus sp. 46600.0 1 PMID:10430027 -6.1.1.21 * synechocystis sp. 49200.0 1 PMID:10430027 -6.1.1.21 * thermus thermophilus 47100.0 1 PMID:10430027 -6.1.1.22 * bos taurus 189000.0 2 PMID:6849897 -6.1.1.22 * cricetulus griseus 155000.0 1 PMID:618867 -6.1.1.22 * fasciola gigantica 132000.0 1 PMID:29031680;PMID:30287492 -6.1.1.22 * geobacillus stearothermophilus 127000.0 3 PMID:690138 -6.1.1.22 * mus musculus 65000.0 1 PMID:19631775 -6.1.1.22 * plasmodium falciparum 295000.0 2 PMID:24196969 -6.1.1.22 * thermus thermophilus 50875.0 2 PMID:8706760 -6.1.1.23 * helicobacter pylori 134000.0 3 PMID:23454362;PMID:32067260 -6.1.1.23 * sulfurisphaera tokodaii 49074.0 1 PMID:17620724 -6.1.1.23 * thermus thermophilus 400000.0 3 PMID:19478435 -6.1.1.24 * methanothermobacter thermautotrophicus 63237.0 1 PMID:20601684 -6.1.1.24 * sinorhizobium meliloti 54166.0 1 PMID:9426192 -6.1.1.26 * methanosarcina mazei 51000.0 2 PMID:17012805 -6.1.1.27 * methanococcus maripaludis 270000.0 1 PMID:25002468 -6.1.1.27 * methanosarcina mazei 255400.0 6 PMID:18559342 -6.1.1.3 * aeropyrum pernix 53120.0 2 PMID:18931432 -6.1.1.3 * arabidopsis thaliana 6600.0 1 PMID:19995731 -6.1.1.3 * bos taurus 206000.0 2 PMID:6849897 -6.1.1.3 * escherichia coli 164000.0 3 PMID:330505;PMID:670153;PMID:8031907 -6.1.1.3 * oryctolagus cuniculus 86000.0 1 PMID:2445566 -6.1.1.3 * rattus norvegicus 154000.0 2 PMID:7459319 -6.1.1.3 * saccharomyces pastorianus 150000.0 2 PMID:330505;PMID:670153;PMID:8031907 -6.1.1.3 * sulfurisphaera tokodaii 63110.0 2 PMID:18931432 -6.1.1.3 * thermus thermophilus 170000.0 3 PMID:330505;PMID:670153;PMID:7589494;PMID:8031907 -6.1.1.4 * aquifex aeolicus 107600.0 10 PMID:11997034;PMID:12196521;PMID:12359246;PMID:16256368 -6.1.1.4 * cricetulus griseus 1200000.0 3 PMID:3971983;PMID:8161568 -6.1.1.4 * cyberlindnera jadinii 150000.0 3 PMID:1100400 -6.1.1.4 * drosophila sp. (in: flies) 1200000.0 1 PMID:3971983;PMID:8161568 -6.1.1.4 * escherichia coli 98500.0 4 PMID:10024478;PMID:10529176 -6.1.1.4 * euglena gracilis 116000.0 5 PMID:6794616;PMID:6805515 -6.1.1.4 * homo sapiens 135000.0 3 PMID:10684970;PMID:16055448;PMID:20805241;PMID:6630191;PMID:7050099 -6.1.1.4 * mycobacterium tuberculosis 108000.0 1 PMID:23268443 -6.1.1.4 * natrialba magadii 107600.0 2 PMID:24500203 -6.1.1.4 * ovis aries 150000.0 2 PMID:3896782 -6.1.1.4 * phaseolus vulgaris 200000.0 6 PMID:20805241;PMID:6630191;PMID:7050099 -6.1.1.4 * pyrococcus horikoshii 113000.0 1 PMID:15388951 -6.1.1.4 * saccharomyces cerevisiae 120000.0 2 PMID:2826465;PMID:4567786 -6.1.1.4 * tetrahymena pyriformis 100000.0 2 PMID:242273 -6.1.1.4 * triticum aestivum 105000.0 2 PMID:679950 -6.1.1.5 * escherichia coli 103000.0 2 PMID:4581276 -6.1.1.5 * geobacillus stearothermophilus 115000.0 1 PMID:4336851 -6.1.1.5 * ovis aries 200000.0 2 PMID:4074679 -6.1.1.5 * thermus thermophilus 129000.0 3 PMID:6468656 -6.1.1.5 * trypanosoma brucei 125900.0 3 PMID:21976735;PMID:23548908 -6.1.1.6 * cricetinae 120000.0 6 PMID:11706011 -6.1.1.6 * escherichia coli 150000.0 5 PMID:11041850;PMID:11946604;PMID:4333590 -6.1.1.6 * geobacillus stearothermophilus 120000.0 8 PMID:10737207;PMID:690138;PMID:8743569;PMID:9644244 -6.1.1.6 * homo sapiens 270000.0 9 PMID:11333884;PMID:17050605;PMID:18272479;PMID:18715867 -6.1.1.6 * myxococcus xanthus 68000.0 1 PMID:26048731 -6.1.1.6 * ovis aries 150000.0 2 PMID:3896782 -6.1.1.6 * plasmodium falciparum 65000.0 1 PMID:23633587 -6.1.1.6 * rattus norvegicus 240000.0 3 PMID:465071;PMID:7372681 -6.1.1.6 * saccharomyces cerevisiae 138000.0 2 PMID:4588881 -6.1.1.7 * bombyx mori 151000.0 4 PMID:6570482;PMID:6706990 -6.1.1.7 * bos taurus 162000.0 2 PMID:6849897 -6.1.1.7 * escherichia coli 380000.0 9 PMID:10441391;PMID:10704215;PMID:21985608;PMID:2407064;PMID:7005211;PMID:8645007 -6.1.1.7 * homo sapiens 83000.0 1 PMID:30952159 -6.1.1.7 * pyrococcus horikoshii 18152.0 1 PMID:16374837 -6.1.1.7 * saccharomyces cerevisiae 153000.0 5 PMID:7013809 -6.1.1.7 * thermus thermophilus 205000.0 3 PMID:12542696;PMID:9207019 -6.1.1.9 * escherichia coli 108100.0 1 PMID:3275660 -6.1.1.9 * euglena gracilis 126000.0 2 PMID:109126;PMID:6155123;PMID:6805515 -6.1.1.9 * geobacillus stearothermophilus 110000.0 2 * -6.1.1.9 * homo sapiens 140000.0 1 PMID:16229838 -6.1.1.9 * mycolicibacterium smegmatis 126000.0 2 PMID:109126;PMID:6155123 -6.1.1.9 * oryctolagus cuniculus 800000.0 4 PMID:2556394;PMID:2556395;PMID:3378054;PMID:3609329 -6.1.1.9 * rattus norvegicus 585000.0 4 PMID:2556395;PMID:3378054 -6.1.1.9 * saccharomyces cerevisiae 140000.0 4 PMID:2556395;PMID:3378054;PMID:7013764 -6.1.1.9 * thermus thermophilus 108000.0 2 PMID:6468656 -6.1.2.1 * enterococcus faecalis 38000.0 1 PMID:7957913 -6.1.2.1 * staphylococcus aureus 82000.0 2 PMID:20729361 -6.1.3.1 * xanthomonas campestris 1900000.0 1 PMID:28223313 -6.2.1.1 * acetobacter aceti 77000.0 2 PMID:12800;PMID:22247508 -6.2.1.1 * archaeoglobus fulgidus 221200.0 2 PMID:17350930 -6.2.1.1 * bos taurus 74309.0 1 PMID:11150295 -6.2.1.1 * bradyrhizobium japonicum 150000.0 2 PMID:1970239 -6.2.1.1 * haloarcula marismortui 89000.0 2 PMID:15947865 -6.2.1.1 * homo sapiens 80000.0 2 PMID:10843999 -6.2.1.1 * ignicoccus hospitalis 670000.0 2 PMID:12800;PMID:22247508 -6.2.1.1 * methanothermobacter thermautotrophicus 144800.0 2 PMID:17350930 -6.2.1.1 * methanothrix soehngenii 148000.0 2 PMID:2571608 -6.2.1.1 * methanothrix thermoacetophila 75000.0 1 PMID:22927778 -6.2.1.1 * mus musculus 78000.0 3 PMID:11150295 -6.2.1.1 * neomoorella thermoacetica 310000.0 1 PMID:18293927 -6.2.1.1 * penicillium chrysogenum 139000.0 2 PMID:1347531;PMID:16790016 -6.2.1.1 * pseudomonas putida 141000.0 2 PMID:1347531;PMID:16790016 -6.2.1.1 * pyrobaculum aerophilum 625000.0 3 PMID:15642362 -6.2.1.1 * saccharomyces cerevisiae 261800.0 7 PMID:13070;PMID:4579873;PMID:6105887;PMID:6116161;PMID:7209 -6.2.1.10 * rattus norvegicus 20000.0 1 * -6.2.1.11 * mycoplana sp. 57000.0 2 PMID:3800379 -6.2.1.12 * acetobacterium woodii 60000.0 1 PMID:21131487 -6.2.1.12 * arabidopsis thaliana 66000.0 1 PMID:10417722 -6.2.1.12 * centaurium erythraea 50000.0 1 PMID:9177055 -6.2.1.12 * erythrina crista-galli 40000.0 1 * -6.2.1.12 * forsythia suspensa 55000.0 1 PMID:4364250;PMID:4699252 -6.2.1.12 * glycine max 55000.0 1 PMID:4364250;PMID:4699252 -6.2.1.12 * hibiscus cannabinus 59560.0 1 * -6.2.1.12 * lathyrus oleraceus 75000.0 1 * -6.2.1.12 * ocimum tenuiflorum 62480.0 1 PMID:23677922 -6.2.1.12 * oryza sativa 86000.0 1 * -6.2.1.12 * petroselinum crispum 67000.0 1 PMID:921295 -6.2.1.12 * physcomitrium patens 65000.0 3 PMID:18722632 -6.2.1.12 * picea abies 63000.0 2 PMID:7075602 -6.2.1.12 * pinus taeda 64000.0 1 PMID:7784527 -6.2.1.12 * populus trichocarpa x populus deltoides 60000.0 1 PMID:9489021 -6.2.1.12 * populus x canadensis 41000.0 1 PMID:24264611 -6.2.1.12 * robinia pseudoacacia 62000.0 1 PMID:15235922 -6.2.1.12 * ruta graveolens 62384.0 2 PMID:18379886 -6.2.1.12 * salix babylonica 57000.0 1 PMID:7075602 -6.2.1.12 * sorbus aucuparia 66200.0 3 PMID:21330005 -6.2.1.13 * chloroflexus aurantiacus 317000.0 4 PMID:24164217 -6.2.1.13 * entamoeba histolytica 150000.0 1 PMID:18372246;PMID:25303954 -6.2.1.13 * giardia duodenalis 78000.0 1 PMID:10375639 -6.2.1.13 * haloarcula marismortui 166000.0 2 PMID:15340786 -6.2.1.13 * halococcus saccharolyticus 150000.0 1 PMID:11409546 -6.2.1.13 * haloferax volcanii 163000.0 2 PMID:11409546;PMID:33558390 -6.2.1.13 * halorubrum saccharovorum 150000.0 1 PMID:11409546 -6.2.1.13 * phycomyces blakesleeanus 77000.0 2 PMID:15921892 -6.2.1.13 * pyrococcus furiosus 165000.0 15 PMID:10482538;PMID:18372246;PMID:25303954;PMID:8830684;PMID:9119024 -6.2.1.14 * ectopseudomonas mendocina 298600.0 2 * -6.2.1.14 * lathyrus oleraceus 53000.0 1 * -6.2.1.14 * lysinibacillus sphaericus 60000.0 2 PMID:1445232 -6.2.1.16 * homo sapiens 75143.0 4 PMID:12623130 -6.2.1.16 * rattus norvegicus 100000.0 3 PMID:2862567;PMID:6539623 -6.2.1.16 * rattus sp. 71000.0 1 PMID:10682835 -6.2.1.16 * sinorhizobium meliloti 72000.0 2 PMID:10735852;PMID:11872708 -6.2.1.16 * zoogloea ramigera 72000.0 1 PMID:7140777 -6.2.1.17 * bos taurus 73400.0 2 PMID:7341659 -6.2.1.17 * chloroflexus aurantiacus 800000.0 2 PMID:11821399 -6.2.1.17 * metallosphaera sedula 340000.0 2 PMID:18165310 -6.2.1.17 * ralstonia solanacearum 70900.0 3 PMID:14706841;PMID:22118660 -6.2.1.17 * salmonella enterica 71300.0 2 PMID:14706841 -6.2.1.17 * salmonella enterica subsp. enterica serovar typhimurium 70000.0 1 * -6.2.1.17 * sulfurisphaera tokodaii 140000.0 2 PMID:18165310 -6.2.1.19 * photobacterium leiognathi 43130.0 1 PMID:8941351 -6.2.1.19 * photobacterium phosphoreum 66000.0 3 * -6.2.1.2 * bos taurus 260000.0 8 PMID:1169176;PMID:3609444;PMID:465508 -6.2.1.2 * mus musculus 65000.0 1 PMID:16378734 -6.2.1.2 * paecilomyces variotii 145000.0 2 * -6.2.1.2 * penicillium chrysogenum 62600.0 1 PMID:18834333 -6.2.1.2 * pseudomonas aeruginosa 142000.0 2 PMID:6800377 -6.2.1.2 * sus scrofa 46500.0 1 PMID:11281196 -6.2.1.20 * escherichia coli 80600.0 2 PMID:10733890;PMID:2540190 -6.2.1.20 * rhodotorula glutinis 35000.0 1 PMID:11716776 -6.2.1.20 * vibrio harveyi 80000.0 3 PMID:16906759;PMID:8384617 -6.2.1.22 * lacrimispora sphenoides 58000.0 2 PMID:3935436 -6.2.1.22 * rubrivivax gelatinosus 41690.0 2 PMID:7128585 -6.2.1.25 * anaerobic bacterium 58000.0 1 PMID:1369492 -6.2.1.25 * clarkia breweri 64500.0 2 PMID:12054436 -6.2.1.25 * geobacter metallireducens 60000.0 1 PMID:16313613 -6.2.1.25 * magnetospirillum sp. 126000.0 3 PMID:16553855 -6.2.1.25 * pseudomonas sp. 130000.0 5 PMID:8335640 -6.2.1.25 * rhodopseudomonas palustris 62000.0 3 PMID:3350788 -6.2.1.25 * thauera aromatica 58000.0 1 PMID:12897012 -6.2.1.26 * escherichia coli 185000.0 2 PMID:8955296 -6.2.1.26 * mycolicibacterium phlei 28000.0 1 PMID:1663748 -6.2.1.27 * anthoceros agrestis 65000.0 1 PMID:32405654 -6.2.1.27 * azoarcus sp. 54000.0 1 PMID:18156265 -6.2.1.27 * centaurium erythraea 50000.0 1 PMID:9177055 -6.2.1.27 * pseudomonas sp. 48000.0 1 PMID:8477728 -6.2.1.27 * thauera aromatica 60000.0 2 PMID:11208796;PMID:18156265 -6.2.1.3 * arabidopsis thaliana 150000.0 2 PMID:23159612;PMID:23288899 -6.2.1.3 * babesia bovis 78000.0 1 PMID:16469396 -6.2.1.3 * brassica napus 76000.0 1 PMID:11785933 -6.2.1.3 * drosophila melanogaster 52500.0 1 PMID:17090919 -6.2.1.3 * escherichia coli 130000.0 7 PMID:1460045;PMID:3888279;PMID:3907712;PMID:7016858 -6.2.1.3 * geobacillus thermodenitrificans 118000.0 2 PMID:22694860 -6.2.1.3 * homo sapiens 75000.0 2 PMID:16834775;PMID:17934335 -6.2.1.3 * mus musculus 150000.0 5 PMID:16469493;PMID:23159612;PMID:23288899;PMID:33485846 -6.2.1.3 * oryctolagus cuniculus 81516.0 1 PMID:12573249 -6.2.1.3 * rattus norvegicus 250000.0 6 PMID:16469493;PMID:17722065;PMID:227853;PMID:2341402;PMID:467438;PMID:7278657 -6.2.1.3 * saccharomyces cerevisiae 145000.0 3 PMID:16798075;PMID:17604220 -6.2.1.3 * yarrowia lipolytica 84000.0 1 * -6.2.1.30 * aromatoleum evansii 52000.0 3 PMID:10629172;PMID:8352645 -6.2.1.30 * penicillium chrysogenum 64000.0 4 PMID:17612506;PMID:18834333;PMID:21625874 -6.2.1.30 * pseudomonas putida 48000.0 1 PMID:2324116 -6.2.1.30 * pseudomonas sp. 52000.0 2 PMID:10629172;PMID:8352645 -6.2.1.30 * thermus thermophilus 110000.0 2 PMID:18414813 -6.2.1.32 * pseudomonas sp. 65000.0 2 PMID:1885526 -6.2.1.33 * arthrobacter sp. 112000.0 2 PMID:15068371 -6.2.1.33 * pseudomonas sp. 125000.0 4 PMID:1418673;PMID:1610806 -6.2.1.36 * erythrobacter sp. nap1 400000.0 1 PMID:30374166 -6.2.1.36 * metallosphaera sedula 340000.0 2 PMID:18165310 -6.2.1.36 * sulfurisphaera tokodaii 140000.0 2 PMID:18165310 -6.2.1.37 * azoarcus sp. 54000.0 2 PMID:18156265 -6.2.1.37 * centaurium erythraea 50000.0 1 PMID:10746747;PMID:9177055 -6.2.1.37 * thauera aromatica 60000.0 2 PMID:11208796;PMID:18156265 -6.2.1.39 * niallia circulans 50969.0 3 PMID:15975512 -6.2.1.4 * pigeon 44500.0 2 PMID:9765290 -6.2.1.4 * sus scrofa 82500.0 6 PMID:4120859 -6.2.1.4 * thermus aquaticus 24520.0 1 PMID:17565180 -6.2.1.40 * metallosphaera sedula 64000.0 2 PMID:23258541 -6.2.1.40 * pyrobaculum neutrophilum 71356.0 1 PMID:21169482 -6.2.1.44 * burkholderia thailandensis 64781.0 1 PMID:24443527 -6.2.1.44 * candidatus pelagibacter communis 108000.0 3 PMID:24443527 -6.2.1.44 * pseudomonas aeruginosa 59548.0 1 PMID:24443527 -6.2.1.44 * ruegeria lacuscaerulensis 59400.0 2 PMID:24443527 -6.2.1.44 * ruegeria pomeroyi 122000.0 7 PMID:21562561;PMID:24443527 -6.2.1.45 * arabidopsis thaliana 124000.0 5 PMID:9076989 -6.2.1.45 * citrus reticulata 49280.0 1 PMID:23154060 -6.2.1.45 * giardia duodenalis 114000.0 3 PMID:22498829 -6.2.1.45 * homo sapiens 118000.0 7 PMID:11195973;PMID:19343538;PMID:1986373;PMID:32315770 -6.2.1.48 * escherichia coli 59311.0 1 PMID:7815937 -6.2.1.48 * proteus sp. (in: enterobacteria) 58600.0 1 PMID:15731894 -6.2.1.5 * acetobacter aceti 55846.0 2 PMID:18502856 -6.2.1.5 * blastocystis sp. 45100.0 3 PMID:18452512 -6.2.1.5 * columba livia 42500.0 2 PMID:9765290 -6.2.1.5 * escherichia coli 141000.0 10 PMID:3002435;PMID:3543212;PMID:4605130 -6.2.1.5 * glycine max 160000.0 1 PMID:5166363 -6.2.1.5 * haloarcula vallismortis 174000.0 1 * -6.2.1.5 * halobacterium salinarum 150000.0 1 * -6.2.1.5 * haloferax volcanii 170000.0 1 * -6.2.1.5 * natronobacterium gregoryi 171000.0 1 * -6.2.1.5 * natronococcus occultus 184000.0 1 * -6.2.1.5 * natronomonas pharaonis 174000.0 1 * -6.2.1.5 * neocallimastix frontalis 330000.0 1 PMID:9003318 -6.2.1.5 * neocallimastix patriciarum 47100.0 2 PMID:16515848 -6.2.1.5 * nitrosomonas europaea 130000.0 3 * -6.2.1.5 * pigeon 100000.0 3 PMID:3940885 -6.2.1.5 * priestia megaterium 75000.0 1 * -6.2.1.5 * saccharolobus solfataricus 35000.0 1 PMID:9514265 -6.2.1.5 * sus scrofa 75000.0 1 * -6.2.1.5 * thermococcus kodakarensis 160000.0 3 PMID:17640871 -6.2.1.5 * thermoplasma acidophilum 68000.0 1 * -6.2.1.5 * thermus aquaticus 150000.0 1 * -6.2.1.57 * mycobacterium tuberculosis 220000.0 1 PMID:36896429 -6.2.1.62 * bacillus anthracis 47000.0 1 PMID:17346033 -6.2.1.7 * eubacterium sp. 58294.0 1 PMID:1551828 -6.2.1.7 * rattus norvegicus 243000.0 3 PMID:8908353;PMID:9390170 -6.2.1.71 * escherichia coli 115000.0 5 PMID:21166461;PMID:2531000 -6.2.1.71 * vibrio anguillarum 60900.0 1 PMID:14758470 -6.2.1.71 * vibrio cholerae 60124.0 2 PMID:22139167 -6.2.1.76 * arabidopsis thaliana 60062.0 1 PMID:21642549 -6.2.1.76 * bradyrhizobium japonicum 58000.0 1 PMID:1847615 -6.2.1.76 * homo sapiens 64940.0 2 PMID:21642549;PMID:21846720 -6.2.1.76 * rhizobium leguminosarum 80000.0 2 PMID:10548546;PMID:9826185 -6.2.1.8 * lathyrus sativus 56000.0 1 PMID:35359497 -6.2.1.9 * pseudomonas sp. 300000.0 5 PMID:429295;PMID:4745770 -6.3.1.1 * escherichia coli 82000.0 1 * -6.3.1.1 * klebsiella aerogenes 80000.0 1 PMID:6125499 -6.3.1.11 * escherichia coli k-12 630000.0 2 PMID:18495664 -6.3.1.11 * haloferax mediterranei 667000.0 1 PMID:34439822 -6.3.1.13 * mycolicibacterium smegmatis 47562.0 3 PMID:17848100 -6.3.1.15 * streptomyces niveus 60000.0 3 PMID:10801869 -6.3.1.17 * mus musculus 42000.0 1 PMID:20657015 -6.3.1.18 * acinetobacter sp. 350000.0 2 PMID:23893114 -6.3.1.2 * [bacillus] caldolyticus 370000.0 2 PMID:6106022 -6.3.1.2 * acidithiobacillus ferrooxidans 60000.0 1 * -6.3.1.2 * bacillus subtilis 600000.0 3 PMID:18195355;PMID:24158439 -6.3.1.2 * bacteroides fragilis 860000.0 4 PMID:16879836 -6.3.1.2 * bifidobacterium bifidum 500000.0 1 PMID:11520611 -6.3.1.2 * bifidobacterium breve 500000.0 1 PMID:11520611 -6.3.1.2 * bifidobacterium pseudolongum 500000.0 1 PMID:11520611 -6.3.1.2 * bradyrhizobium japonicum 760000.0 4 PMID:20504761 -6.3.1.2 * brassica napus 41978.0 1 PMID:7911583 -6.3.1.2 * canis lupus familiaris 49000.0 2 PMID:14583610 -6.3.1.2 * chlorella sorokiniana 398000.0 4 PMID:16664139 -6.3.1.2 * clostridium acetobutylicum 59000.0 1 PMID:16347143 -6.3.1.2 * clostridium pasteurianum 1000000.0 2 PMID:2871863 -6.3.1.2 * drosophila melanogaster 377600.0 1 PMID:33327463 -6.3.1.2 * enchytraeus japonensis 40509.0 1 PMID:18183418 -6.3.1.2 * escherichia coli 51800.0 1 PMID:8520480 -6.3.1.2 * gluconacetobacter diazotrophicus 500000.0 2 PMID:11520611 -6.3.1.2 * gordonia rubripertincta 56000.0 1 PMID:2569461;PMID:2906794 -6.3.1.2 * haloferax mediterranei 580000.0 4 PMID:17020556;PMID:23069245 -6.3.1.2 * helicobacter pylori 56000.0 2 PMID:9573059 -6.3.1.2 * homo sapiens 400000.0 4 PMID:11080211;PMID:17138698;PMID:17368308;PMID:8551033 -6.3.1.2 * lathyrus oleraceus 520000.0 4 * -6.3.1.2 * leptolyngbya laminosa 602000.0 1 PMID:2563365 -6.3.1.2 * lupinus luteus 347000.0 2 * -6.3.1.2 * medicago truncatula 47212.0 4 PMID:16831848;PMID:20723225 -6.3.1.2 * methanosarcina mazei 45000.0 1 PMID:15752204 -6.3.1.2 * methylococcus capsulatus 617000.0 2 * -6.3.1.2 * mycobacterium tuberculosis 680000.0 7 PMID:12146952;PMID:16262797;PMID:7937767 -6.3.1.2 * mycolicibacterium phlei 670000.0 2 PMID:2569461;PMID:2870058;PMID:2906794 -6.3.1.2 * mycolicibacterium smegmatis 58000.0 1 PMID:18826970 -6.3.1.2 * nicotiana plumbaginifolia 305000.0 2 * -6.3.1.2 * nitrobacter winogradskyi 700000.0 2 * -6.3.1.2 * nocardia asteroides 720000.0 2 PMID:7663309 -6.3.1.2 * paracoccus denitrificans 570000.0 2 PMID:1356141 -6.3.1.2 * phaseolus vulgaris 350000.0 5 PMID:10487218;PMID:10491091;PMID:16884924 -6.3.1.2 * photobacterium phosphoreum 670000.0 2 PMID:2569461;PMID:2870058 -6.3.1.2 * providencia vermicola 600000.0 1 PMID:30353099 -6.3.1.2 * pseudomonas aeruginosa 62000.0 1 PMID:6111557 -6.3.1.2 * pseudomonas fluorescens 62000.0 1 PMID:6111557 -6.3.1.2 * pseudomonas putida 61000.0 1 PMID:6111557 -6.3.1.2 * pseudomonas syringae 60000.0 1 * -6.3.1.2 * pseudomonas taetrolens 66000.0 2 PMID:15388964 -6.3.1.2 * pyrococcus sp. 637000.0 1 PMID:9172372 -6.3.1.2 * rattus norvegicus 44000.0 3 PMID:17368308;PMID:21254280;PMID:2868383 -6.3.1.2 * rhizobium phaseoli 891000.0 3 * -6.3.1.2 * rhodobacter capsulatus 670000.0 2 PMID:2859272 -6.3.1.2 * rhodospirillum rubrum 530000.0 2 PMID:2562919 -6.3.1.2 * saccharolobus solfataricus 53348.0 1 PMID:1973523 -6.3.1.2 * schistosoma japonicum 45000.0 2 PMID:23011789 -6.3.1.2 * secale cereale x triticum aestivum 385200.0 4 PMID:7732756 -6.3.1.2 * sinorhizobium meliloti 355000.0 3 PMID:8093245 -6.3.1.2 * skeletonema costatum 400000.0 2 PMID:8756499 -6.3.1.2 * solanum lycopersicum 45000.0 2 PMID:16513209 -6.3.1.2 * solanum tuberosum 45000.0 2 PMID:15642719 -6.3.1.2 * sphagnum fallax 492000.0 3 * -6.3.1.2 * spinacia oleracea 360000.0 2 PMID:16664546 -6.3.1.2 * squalus acanthias 400000.0 3 PMID:2860871 -6.3.1.2 * sulfolobus acidocaldarius 630000.0 3 PMID:9865608 -6.3.1.2 * synechocystis sp. 624000.0 5 PMID:7906687;PMID:9063472 -6.3.1.2 * thermotoga maritima 590000.0 1 PMID:1348781 -6.3.1.2 * thermus thermophilus 537000.0 2 PMID:9931254 -6.3.1.2 * trichormus variabilis 625000.0 3 PMID:12732949 -6.3.1.2 * triticum aestivum 46700.0 13 PMID:18288574 -6.3.1.2 * tuber borchii 340000.0 3 PMID:12683951 -6.3.1.2 * xylanibacter ruminicola 83000.0 4 PMID:22020637 -6.3.1.2 * zea mays 350000.0 4 PMID:11080211;PMID:17138698;PMID:8939884 -6.3.1.20 * arabidopsis thaliana 30000.0 1 PMID:24872381 -6.3.1.20 * escherichia coli 47000.0 4 PMID:1765143;PMID:7639702;PMID:8206909 -6.3.1.20 * plasmodium berghei 45000.0 1 PMID:19434237 -6.3.1.20 * plasmodium falciparum 45000.0 1 PMID:19434237 -6.3.1.20 * streptomyces coelicolor 40000.0 1 PMID:25631049 -6.3.1.20 * thermococcus kodakarensis 39100.0 2 PMID:35736229 -6.3.1.20 * thermoplasma acidophilum 41100.0 5 PMID:19520844;PMID:19594830 -6.3.1.21 * mycobacterium tuberculosis 90000.0 1 PMID:31894729 -6.3.1.5 * azospirillum brasilense 600000.0 3 PMID:29581233 -6.3.1.5 * bacillus subtilis 60480.0 2 PMID:7890752;PMID:8916230 -6.3.1.5 * escherichia coli 35000.0 1 PMID:10544053 -6.3.1.5 * geobacillus stearothermophilus 50000.0 2 PMID:12450114 -6.3.1.5 * herbaspirillum seropedicae 85000.0 1 PMID:29581233 -6.3.1.5 * streptococcus sobrinus 38000.0 1 PMID:14702311 -6.3.1.6 * camellia sinensis var. sinensis 49300.0 1 PMID:34775761 -6.3.1.7 * arachis hypogaea 280000.0 3 PMID:3015960;PMID:6838571 -6.3.1.8 * crithidia fasciculata 90000.0 7 PMID:12049631;PMID:1304372;PMID:9677355 -6.3.1.8 * escherichia coli 138000.0 2 PMID:17124497 -6.3.1.9 * crithidia fasciculata 87000.0 3 PMID:1304372;PMID:2354163 -6.3.1.9 * leishmania donovani 74500.0 1 PMID:22050226 -6.3.1.9 * trypanosoma cruzi 74500.0 6 PMID:12121990;PMID:31200083 -6.3.2.1 * escherichia coli 70000.0 5 PMID:11377204;PMID:11669627;PMID:374975;PMID:780351 -6.3.2.1 * fusarium oxysporum 43000.0 1 PMID:11523810 -6.3.2.1 * lotus japonicus 72800.0 2 * -6.3.2.1 * mycobacterium tuberculosis 65000.0 4 PMID:11377204;PMID:11669627;PMID:12717031 -6.3.2.1 * oryza sativa 33900.0 1 * -6.3.2.11 * gallus gallus 250000.0 3 PMID:20097752;PMID:7306555 -6.3.2.11 * mus musculus 430000.0 1 PMID:20097752 -6.3.2.12 * arabidopsis thaliana 53000.0 1 PMID:11752472 -6.3.2.12 * corynebacterium sp. 53000.0 2 PMID:3084914 -6.3.2.12 * lathyrus oleraceus 56000.0 1 PMID:239104 -6.3.2.12 * plasmodium falciparum 90000.0 3 PMID:20350571 -6.3.2.12 * serratia indica 47000.0 1 PMID:9496 -6.3.2.13 * escherichia coli 62000.0 2 PMID:2269304 -6.3.2.13 * pseudomonas aeruginosa 55000.0 1 PMID:19400768 -6.3.2.13 * thermotoga maritima 56000.0 1 PMID:16595662 -6.3.2.14 * escherichia coli 66000.0 2 PMID:9485415 -6.3.2.16 * lacticaseibacillus casei 58000.0 1 PMID:4399593 -6.3.2.17 * bos taurus 73000.0 1 PMID:1760159 -6.3.2.17 * corynebacterium sp. 53000.0 2 PMID:3084914;PMID:6412521;PMID:6458762;PMID:6892912 -6.3.2.17 * datura inoxia 68000.0 1 PMID:7772303 -6.3.2.17 * escherichia coli 48000.0 3 PMID:2985605 -6.3.2.17 * homo sapiens 61000.0 3 PMID:1409616;PMID:8304201;PMID:9250977 -6.3.2.17 * lacticaseibacillus casei 43000.0 2 PMID:3084914;PMID:6138353 -6.3.2.17 * lathyrus oleraceus 68000.0 1 PMID:7772303 -6.3.2.17 * mus musculus 65000.0 3 PMID:11772020;PMID:6548641 -6.3.2.17 * mycobacterium tuberculosis 51000.0 2 PMID:16754987 -6.3.2.17 * neurospora crassa 68000.0 3 PMID:7772303 -6.3.2.17 * saccharomyces cerevisiae 62000.0 1 * -6.3.2.17 * sus scrofa 66000.0 2 * -6.3.2.2 * [candida] boidinii 60000.0 1 PMID:10218110 -6.3.2.2 * acidithiobacillus ferrooxidans 49300.0 1 PMID:10218110 -6.3.2.2 * arabidopsis thaliana 106000.0 3 PMID:10218110;PMID:15180996;PMID:30877193 -6.3.2.2 * ascaris suum 100000.0 2 PMID:8538700 -6.3.2.2 * bos taurus 73000.0 2 PMID:10218110 -6.3.2.2 * drosophila melanogaster 140000.0 3 PMID:12954617 -6.3.2.2 * escherichia coli 58200.0 3 PMID:10218110;PMID:2895925 -6.3.2.2 * homo sapiens 114000.0 9 PMID:10218110;PMID:10741850;PMID:18812186;PMID:8106072;PMID:9637733 -6.3.2.2 * leishmania tarentolae 78100.0 1 PMID:10218110 -6.3.2.2 * mus musculus 73000.0 7 PMID:10218110;PMID:10741850;PMID:18812186;PMID:9224945 -6.3.2.2 * myxococcus xanthus 41000.0 1 PMID:35277888 -6.3.2.2 * nicotiana tabacum 60000.0 3 PMID:10218110;PMID:24202107 -6.3.2.2 * nostoc sp. 45000.0 1 PMID:15695431 -6.3.2.2 * onchocerca volvulus 74200.0 1 PMID:11163433 -6.3.2.2 * ovis aries 78000.0 3 PMID:10218110;PMID:6108786 -6.3.2.2 * pasteurella multocida 220000.0 3 PMID:16339152 -6.3.2.2 * plasmodium berghei 120000.0 3 PMID:19567234 -6.3.2.2 * proteus mirabilis 64000.0 2 PMID:10218110 -6.3.2.2 * pseudoalteromonas haloplanktis 54500.0 1 PMID:24864035 -6.3.2.2 * rattus norvegicus 104000.0 18 PMID:10218110;PMID:10702364;PMID:10741850;PMID:15992;PMID:18812186;PMID:2868388;PMID:2868389;PMID:6146611;PMID:6149706;PMID:8103521;PMID:8104188 -6.3.2.2 * saccharomyces cerevisiae 78300.0 2 PMID:10218110;PMID:10741850 -6.3.2.2 * schizosaccharomyces pombe 71400.0 1 PMID:10218110 -6.3.2.2 * streptococcus agalactiae 70000.0 1 PMID:15642737 -6.3.2.2 * streptococcus thermophilus 80000.0 1 PMID:20233332 -6.3.2.2 * sus scrofa 73000.0 2 PMID:10218110 -6.3.2.2 * synechocystis sp. 46000.0 2 PMID:23170977 -6.3.2.2 * trypanosoma brucei 77500.0 1 PMID:10218110 -6.3.2.23 * glycine max 50000.0 1 PMID:19948790 -6.3.2.23 * lotus japonicus 50000.0 1 PMID:22442424 -6.3.2.23 * medicago sativa 50000.0 1 PMID:22442424 -6.3.2.23 * phaseolus vulgaris 50000.0 1 PMID:22442424 -6.3.2.23 * vigna radiata var. radiata 85000.0 1 * -6.3.2.24 * rattus norvegicus 300000.0 2 PMID:3597366;PMID:8545258;PMID:8735966 -6.3.2.25 * bos taurus 35000.0 1 PMID:861204 -6.3.2.25 * homo sapiens 45000.0 1 PMID:19459643 -6.3.2.25 * sus scrofa 46000.0 8 PMID:10685598;PMID:11004583;PMID:3821560;PMID:3965474;PMID:7390974;PMID:8093886;PMID:9118990 -6.3.2.26 * actinomyces sp. 560000.0 4 PMID:19374992 -6.3.2.26 * amycolatopsis lactamdurans 430000.0 3 PMID:32275728;PMID:7763859;PMID:8973642 -6.3.2.26 * aspergillus nidulans 422500.0 2 PMID:11851475;PMID:2061333 -6.3.2.26 * hapsidospora chrysogena 425000.0 3 PMID:7763859;PMID:9558329 -6.3.2.26 * lysobacter lactamgenus 411500.0 1 PMID:7763859 -6.3.2.26 * penicillium chrysogenum 470000.0 2 PMID:7763859 -6.3.2.29 * nostoc ellipsosporum 210000.0 1 PMID:18977318 -6.3.2.29 * synechococcus sp. ma19 100600.0 2 PMID:11772614 -6.3.2.29 * thermosynechococcus vestitus 400000.0 3 PMID:18679674;PMID:31095967 -6.3.2.29 * trichormus variabilis 230000.0 2 PMID:31095967;PMID:9652408 -6.3.2.29 * uncultured bacterium 100000.0 2 PMID:23579730 -6.3.2.3 * [candida] boidinii 120000.0 2 PMID:12734194;PMID:447639;PMID:8192897 -6.3.2.3 * bos taurus 122000.0 2 PMID:5066150 -6.3.2.3 * clostridium acetobutylicum 85000.0 1 PMID:17123467 -6.3.2.3 * escherichia coli 152000.0 2 PMID:6389479;PMID:9880348 -6.3.2.3 * homo sapiens 52352.0 1 PMID:7646467 -6.3.2.3 * lathyrus oleraceus 85000.0 1 * -6.3.2.3 * myxococcus xanthus 78000.0 1 PMID:35277888 -6.3.2.3 * pasteurella multocida 220000.0 5 PMID:16339152 -6.3.2.3 * plasmodium berghei 70000.0 1 PMID:21377539 -6.3.2.3 * pseudoalteromonas haloplanktis 74000.0 4 PMID:22016660;PMID:22777241 -6.3.2.3 * rattus norvegicus 118000.0 3 PMID:447639;PMID:7862666 -6.3.2.3 * saccharomyces cerevisiae 123000.0 3 * -6.3.2.3 * schizosaccharomyces pombe 120000.0 4 PMID:12734194;PMID:8192897;PMID:9291132 -6.3.2.3 * streptococcus agalactiae 88000.0 2 PMID:15642737;PMID:16939198 -6.3.2.3 * streptococcus thermophilus 80000.0 1 PMID:20233332 -6.3.2.3 * synechocystis sp. 150000.0 2 PMID:23170977 -6.3.2.30 * nostoc ellipsosporum 210000.0 1 PMID:18977318 -6.3.2.30 * synechococcus sp. ma19 100600.0 2 PMID:11772614 -6.3.2.30 * synechocystis sp. 100000.0 2 PMID:20038708 -6.3.2.30 * synechocystis sp. pcc 6803 240000.0 2 PMID:11319097 -6.3.2.30 * thermosynechococcus vestitus 400000.0 3 PMID:18679674;PMID:31095967 -6.3.2.30 * trichormus variabilis 265000.0 3 PMID:26781249;PMID:31095967;PMID:9652408 -6.3.2.30 * uncultured bacterium 100000.0 2 PMID:23579730 -6.3.2.31 * methanocaldococcus jannaschii 52100.0 2 PMID:12911320 -6.3.2.32 * methanocaldococcus jannaschii 37000.0 3 PMID:12909715 -6.3.2.33 * methanocaldococcus jannaschii 72000.0 3 PMID:12909715 -6.3.2.34 * methanocaldococcus jannaschii 52100.0 2 PMID:12911320 -6.3.2.35 * enterococcus faecalis 39947.0 2 PMID:19851013 -6.3.2.36 * thermococcus kodakarensis 60000.0 2 PMID:19666462;PMID:24638914 -6.3.2.37 * thermotoga maritima 56000.0 1 PMID:16595662 -6.3.2.38 * escherichia coli 63000.0 2 PMID:2935523;PMID:3003525 -6.3.2.39 * escherichia coli 63000.0 2 PMID:2935523;PMID:3003525 -6.3.2.4 * enterococcus faecalis 38000.0 1 PMID:7957913 -6.3.2.4 * salmonella enterica subsp. enterica serovar typhimurium 42000.0 2 PMID:2841972 -6.3.2.41 * mus musculus 43000.0 4 PMID:20657015;PMID:21454531 -6.3.2.42 * mus musculus 42000.0 1 PMID:21454531 -6.3.2.44 * methanosarcina mazei 57000.0 2 PMID:18422645 -6.3.2.45 * escherichia coli 50961.0 3 PMID:17384195 -6.3.2.48 * bacillus subtilis 80000.0 3 PMID:19352016 -6.3.2.49 * bacillus subtilis 105000.0 3 PMID:16030213;PMID:22298000 -6.3.2.49 * ralstonia solanacearum 49500.0 1 PMID:18445480 -6.3.2.5 * enterococcus faecalis 60000.0 2 PMID:19182993 -6.3.2.5 * escherichia coli 45000.0 3 PMID:11278255;PMID:12140293 -6.3.2.5 * rattus norvegicus 37000.0 1 * -6.3.2.50 * pyricularia oryzae 173000.0 1 PMID:26503170 -6.3.2.51 * enterococcus faecalis 60000.0 3 PMID:19182993 -6.3.2.51 * homo sapiens 70000.0 2 PMID:19683078;PMID:29754768 -6.3.2.6 * bacillus anthracis 55000.0 1 PMID:26118696 -6.3.2.6 * bacillus subtilis 27431.0 1 PMID:3036807 -6.3.2.6 * escherichia coli 76000.0 4 PMID:1534690;PMID:2120198;PMID:6365889 -6.3.2.6 * gallus gallus 350000.0 2 PMID:4772278 -6.3.2.6 * homo sapiens 400000.0 1 PMID:35285625 -6.3.2.6 * ovis aries 420000.0 2 PMID:1781372 -6.3.2.6 * saccharomyces cerevisiae 35500.0 1 PMID:1447788 -6.3.2.6 * streptococcus pneumoniae 56000.0 1 PMID:26118696 -6.3.2.6 * streptococcus suis 26600.0 1 PMID:20693665 -6.3.2.6 * trichoplusia ni 360000.0 2 PMID:23553965 -6.3.2.61 * mus musculus 360000.0 1 PMID:9622491 -6.3.2.65 * bacillus cereus 41900.0 1 PMID:25368324 -6.3.2.8 * chlamydia trachomatis 65000.0 3 PMID:14594822 -6.3.2.8 * corynebacterium glutamicum 52000.0 1 PMID:18974047 -6.3.2.8 * escherichia coli 100000.0 10 PMID:12876369;PMID:7601127;PMID:8634272;PMID:9158719;PMID:9600257 -6.3.2.8 * staphylococcus aureus 40000.0 1 PMID:4756894 -6.3.2.8 * thermotoga maritima 51740.0 1 PMID:15146505 -6.3.2.9 * escherichia coli 52000.0 3 PMID:2179861;PMID:3301347;PMID:9524242;PMID:9631510 -6.3.2.9 * pseudomonas aeruginosa 51000.0 1 PMID:16517013 -6.3.2.9 * staphylococcus aureus 52000.0 1 PMID:3301347;PMID:9524242 -6.3.3.1 * bacillus subtilis 37057.0 1 PMID:3036807 -6.3.3.1 * escherichia coli 71700.0 3 PMID:3015935;PMID:3530323 -6.3.3.1 * gallus gallus 330000.0 2 PMID:3756144 -6.3.3.1 * saccharomyces cerevisiae 87000.0 1 PMID:8600995 -6.3.3.1 * schizosaccharomyces pombe 240000.0 2 PMID:967158 -6.3.3.1 * vigna unguiculata 75900.0 5 PMID:12644656;PMID:9520274 -6.3.3.2 * arabidopsis thaliana 27000.0 2 PMID:12207015 -6.3.3.2 * homo sapiens 27000.0 6 PMID:15243192;PMID:3801490;PMID:6433660;PMID:7766710;PMID:8522195;PMID:9250980 -6.3.3.2 * lacticaseibacillus casei 23000.0 1 PMID:6421815;PMID:6433660 -6.3.3.2 * mus musculus 25220.0 3 PMID:15135403;PMID:17055997 -6.3.3.2 * mycoplasmoides pneumoniae 44000.0 2 PMID:16104022 -6.3.3.2 * oryctolagus cuniculus 29000.0 3 PMID:3801490;PMID:6433660;PMID:6609158 -6.3.3.3 * escherichia coli 42000.0 2 PMID:374977;PMID:4921568 -6.3.3.3 * serratia marcescens 25000.0 1 PMID:8969526 -6.3.3.4 * streptomyces clavuligerus 56000.0 2 PMID:12413541 -6.3.3.5 * streptomyces lavendulae 34000.0 2 PMID:23529730 -6.3.3.6 * pectobacterium carotovorum 235000.0 4 PMID:12820893;PMID:12890666 -6.3.4.10 * arabidopsis thaliana 41172.0 1 PMID:9173880 -6.3.4.10 * bos taurus 64000.0 3 PMID:8053691;PMID:9211291 -6.3.4.10 * homo sapiens 115000.0 5 PMID:19740736;PMID:21802411;PMID:9211291 -6.3.4.10 * oryctolagus cuniculus 85000.0 1 PMID:9211291 -6.3.4.12 * methyloversatilis universalis 48820.0 1 PMID:19943898 -6.3.4.12 * methylovorus mays 50000.0 3 PMID:18175924;PMID:32885332 -6.3.4.13 * bacillus subtilis 45253.0 1 PMID:3036807 -6.3.4.13 * drosophila melanogaster 45000.0 1 PMID:3673708 -6.3.4.13 * escherichia coli 49000.0 4 PMID:2182115;PMID:3673708;PMID:9843369 -6.3.4.13 * geobacillus kaustophilus 50000.0 1 PMID:20716513 -6.3.4.13 * homo sapiens 112000.0 1 PMID:3718932 -6.3.4.13 * mus musculus 110000.0 1 PMID:8299947 -6.3.4.13 * salmonella enterica subsp. enterica serovar typhimurium 82000.0 2 * -6.3.4.13 * schizosaccharomyces pombe 40000.0 1 PMID:3673708 -6.3.4.13 * thermus thermophilus 45000.0 1 PMID:20716513 -6.3.4.14 * aquifex aeolicus 50000.0 1 PMID:10079084;PMID:10542197;PMID:10747803;PMID:11346647;PMID:14993673 -6.3.4.14 * corynebacterium glutamicum 63400.0 1 PMID:8772169 -6.3.4.14 * escherichia coli 95000.0 9 PMID:10079084;PMID:10542197;PMID:10747803;PMID:11346647;PMID:11390406;PMID:14960587;PMID:14993673;PMID:1682920;PMID:23499019;PMID:235702;PMID:2971391;PMID:4154089;PMID:4922289;PMID:9637261 -6.3.4.14 * jatropha curcas 58300.0 1 PMID:21421413 -6.3.4.14 * mycosarcoma maydis 64700.0 1 PMID:14766011 -6.3.4.14 * myxococcus xanthus 65000.0 2 PMID:10986250 -6.3.4.14 * sulfuracidifex metallicus 60000.0 2 PMID:10591844 -6.3.4.15 * candida albicans 73000.0 1 PMID:18809372 -6.3.4.15 * escherichia coli 35310.0 3 PMID:11714929;PMID:16321044;PMID:16480719 -6.3.4.15 * escherichia coli k-12 35500.0 1 PMID:12236345 -6.3.4.15 * homo sapiens 265000.0 2 PMID:17904341;PMID:18442489 -6.3.4.15 * mycobacterium tuberculosis 56000.0 2 * -6.3.4.15 * pyrococcus horikoshii 53900.0 5 PMID:16510991;PMID:17401210;PMID:20499837 -6.3.4.15 * staphylococcus aureus 76000.0 3 PMID:24261685;PMID:30808984 -6.3.4.15 * sulfurisphaera tokodaii 26630.0 1 PMID:16480719 -6.3.4.16 * aquarana catesbeiana 160000.0 1 PMID:213431 -6.3.4.16 * bos taurus 250000.0 2 PMID:4753763 -6.3.4.16 * homo sapiens 202000.0 7 PMID:18026163;PMID:23649895;PMID:6249820;PMID:7248316 -6.3.4.16 * methanobrevibacter smithii 91000.0 3 PMID:23107800 -6.3.4.16 * phycomyces blakesleeanus 188000.0 3 PMID:3395622 -6.3.4.16 * pyrococcus abyssi 50700.0 3 PMID:11523892;PMID:8617264 -6.3.4.16 * pyrococcus furiosus 80000.0 2 PMID:9371756 -6.3.4.16 * ranoidea caerulea 163700.0 1 PMID:22736308 -6.3.4.16 * rattus norvegicus 251000.0 7 PMID:11577071;PMID:17669278;PMID:182079;PMID:206435;PMID:7272272 -6.3.4.18 * escherichia coli 79000.0 3 PMID:1534690 -6.3.4.2 * bos taurus 263000.0 4 PMID:692405;PMID:932036 -6.3.4.2 * drosophila melanogaster 70000.0 1 PMID:21840216;PMID:23459760;PMID:24503052 -6.3.4.2 * escherichia coli 210000.0 7 PMID:10899599;PMID:17600152;PMID:357909;PMID:6349684 -6.3.4.2 * homo sapiens 70000.0 2 PMID:10899599;PMID:21840216;PMID:23459760;PMID:24503052 -6.3.4.2 * lactococcus lactis 280000.0 3 PMID:11500486;PMID:12706337 -6.3.4.2 * mus musculus 122000.0 6 PMID:10899599;PMID:21840216;PMID:23459760;PMID:24503052;PMID:3995044;PMID:7306558 -6.3.4.2 * plasmodium falciparum 100000.0 1 PMID:16051382 -6.3.4.2 * saccharomyces cerevisiae 68000.0 3 PMID:10899599;PMID:8075080 -6.3.4.2 * trypanosoma brucei 70000.0 1 PMID:21840216;PMID:23459760;PMID:24503052 -6.3.4.20 * bacillus subtilis 164000.0 1 PMID:34699108 -6.3.4.21 * escherichia coli 46000.0 2 PMID:22975127;PMID:23740313 -6.3.4.21 * homo sapiens 110000.0 8 PMID:17604275;PMID:21742010;PMID:4349867 -6.3.4.21 * rattus norvegicus 51000.0 1 PMID:17604275 -6.3.4.21 * saccharomyces cerevisiae 45000.0 2 PMID:4324895;PMID:6224784 -6.3.4.21 * salmonella enterica subsp. enterica serovar typhimurium 45540.0 4 PMID:10506999;PMID:7503993;PMID:9521740 -6.3.4.21 * sus scrofa 120000.0 2 * -6.3.4.21 * thermoplasma acidophilum 43000.0 1 PMID:15753098 -6.3.4.24 * methanocaldococcus fervens 33000.0 1 PMID:25211225 -6.3.4.3 * clostridium cylindrosporum 240000.0 1 PMID:7374504 -6.3.4.3 * homo sapiens 143000.0 4 PMID:16171773;PMID:18996079 -6.3.4.3 * lathyrus oleraceus 110000.0 2 PMID:8304211 -6.3.4.3 * methylorubrum extorquens 240000.0 3 PMID:11087401;PMID:14645277;PMID:32505353 -6.3.4.3 * neomoorella thermoacetica 60000.0 3 PMID:11087401;PMID:14645277;PMID:2200509;PMID:22109967 -6.3.4.3 * ovis aries 226000.0 2 PMID:6990198 -6.3.4.3 * rattus norvegicus 107000.0 1 PMID:18996079 -6.3.4.3 * saccharomyces cerevisiae 201000.0 2 PMID:6990198 -6.3.4.3 * spinacia oleracea 130000.0 3 PMID:1644815;PMID:1917961 -6.3.4.3 * sus scrofa 150000.0 2 PMID:6990198 -6.3.4.4 * arabidopsis thaliana 55000.0 1 PMID:10669609 -6.3.4.4 * azotobacter vinelandii 110000.0 2 PMID:21629 -6.3.4.4 * cryptococcus neoformans 46000.0 1 PMID:23989157 -6.3.4.4 * escherichia coli 141000.0 5 PMID:10218106;PMID:3038024;PMID:3045328;PMID:9632649 -6.3.4.4 * helicobacter pylori 96500.0 1 PMID:30191734 -6.3.4.4 * leishmania donovani 250000.0 1 PMID:468834 -6.3.4.4 * methanocaldococcus jannaschii 160000.0 6 PMID:17929831;PMID:18786660 -6.3.4.4 * mus musculus 101100.0 6 PMID:12482871;PMID:18544163 -6.3.4.4 * oryctolagus cuniculus 105000.0 1 PMID:692386 -6.3.4.4 * plasmodium falciparum 105000.0 6 PMID:12071700;PMID:20654742;PMID:22289630 -6.3.4.4 * pyrococcus horikoshii 80000.0 1 PMID:22139164 -6.3.4.4 * rattus norvegicus 104000.0 5 PMID:18452;PMID:6347525;PMID:7213642 -6.3.4.4 * saccharomyces cerevisiae 77000.0 3 * -6.3.4.4 * triticum aestivum 55000.0 1 PMID:10669609 -6.3.4.4 * zea mays 50000.0 3 PMID:9193088 -6.3.4.5 * agaricus bisporus 47270.0 1 PMID:17512708 -6.3.4.5 * bos taurus 185000.0 5 PMID:4355767;PMID:6885737;PMID:6957859;PMID:885853 -6.3.4.5 * escherichia coli 50000.0 1 * -6.3.4.5 * homo sapiens 185000.0 8 PMID:21481813;PMID:518841;PMID:6766737;PMID:6885737;PMID:6957859;PMID:762042;PMID:8792870;PMID:885853 -6.3.4.5 * leishmania donovani 49000.0 2 PMID:23094117 -6.3.4.5 * mus musculus 47000.0 4 PMID:11406294;PMID:16420741;PMID:19491403;PMID:21481813 -6.3.4.5 * pyropia yezoensis 48500.0 1 * -6.3.4.5 * rattus norvegicus 207000.0 5 PMID:118168;PMID:405380;PMID:5300;PMID:9879717 -6.3.4.5 * saccharomyces cerevisiae 228000.0 2 PMID:35347 -6.3.4.5 * sus scrofa 80000.0 2 PMID:1372742 -6.3.4.5 * thermus thermophilus 44815.0 2 PMID:11844799;PMID:12684518 -6.3.4.6 * cyberlindnera jadinii 520000.0 3 PMID:14157 -6.3.4.6 * kluyveromyces lactis 500000.0 3 PMID:22277658;PMID:29263142 -6.3.4.6 * saccharomyces cerevisiae 204000.0 2 PMID:1802034;PMID:6124544 -6.3.4.9 * propionibacterium freudenreichii subsp. shermanii 30000.0 1 PMID:3360240 -6.3.5.1 * azospirillum brasilense 600000.0 2 PMID:29581233 -6.3.5.1 * herbaspirillum seropedicae 548000.0 2 PMID:26802007;PMID:29581233 -6.3.5.1 * homo sapiens 500000.0 3 PMID:12547821;PMID:2107886 -6.3.5.1 * mycobacterium tuberculosis 600000.0 3 PMID:12182838;PMID:9620974 -6.3.5.1 * saccharomyces cerevisiae 630000.0 3 PMID:4340699 -6.3.5.10 * escherichia coli 57000.0 1 PMID:10966576;PMID:12195810 -6.3.5.10 * pseudomonas denitrificans (nom. rej.) 97300.0 6 PMID:10966576;PMID:12195810;PMID:1655697;PMID:1917839 -6.3.5.11 * pseudomonas denitrificans (nom. rej.) 86000.0 2 PMID:2172209 -6.3.5.11 * salmonella enterica subsp. enterica serovar typhimurium 53000.0 3 PMID:15311923 -6.3.5.13 * staphylococcus aureus 72000.0 1 PMID:30154570 -6.3.5.2 * aspergillus fumigatus 120000.0 2 PMID:35102890;PMID:8208731 -6.3.5.2 * dictyostelium discoideum 79600.0 1 PMID:1885577 -6.3.5.2 * escherichia coli 128000.0 7 PMID:211374;PMID:35102890;PMID:3894345;PMID:3911001;PMID:4560421;PMID:4611428;PMID:8208731 -6.3.5.2 * homo sapiens 77360.0 3 PMID:23816837;PMID:8089153;PMID:8527935 -6.3.5.2 * mus musculus 85000.0 1 PMID:211375;PMID:240826 -6.3.5.2 * mycobacterium tuberculosis 137000.0 2 PMID:22119138 -6.3.5.2 * plasmodium falciparum 160000.0 2 PMID:17868038 -6.3.5.2 * rattus norvegicus 83000.0 2 PMID:3436958;PMID:6260205 -6.3.5.3 * bacillus subtilis 80300.0 2 PMID:3036807 -6.3.5.3 * escherichia coli 141418.0 1 PMID:2659070 -6.3.5.3 * gallus gallus 135000.0 2 PMID:357893;PMID:4355768 -6.3.5.3 * pigeon 135000.0 1 PMID:357893;PMID:4355768 -6.3.5.3 * salmonella enterica subsp. enterica serovar typhimurium 140000.0 2 PMID:24223728;PMID:357893;PMID:4355768 -6.3.5.4 * bombyx mori 62800.0 1 PMID:23633098 -6.3.5.4 * bos taurus 120000.0 4 PMID:2858178;PMID:2868008 -6.3.5.4 * escherichia coli 62666.0 1 PMID:1973930 -6.3.5.4 * glycine max 65608.0 3 PMID:9037148;PMID:9501527 -6.3.5.4 * homo sapiens 64800.0 3 PMID:17409444;PMID:34080208 -6.3.5.4 * hordeum vulgare 65500.0 3 PMID:12890559 -6.3.5.4 * klebsiella aerogenes 230000.0 2 PMID:6125499 -6.3.5.4 * leishmania infantum 78800.0 1 PMID:26771178 -6.3.5.4 * lupinus luteus 320000.0 2 * -6.3.5.4 * mus musculus 105000.0 2 PMID:35419 -6.3.5.4 * oryza sativa 66000.0 1 PMID:10965944 -6.3.5.4 * phaseolus vulgaris 65810.0 3 PMID:10209260;PMID:11506363;PMID:19130295 -6.3.5.4 * pinus pinaster 66800.0 2 PMID:22654888 -6.3.5.4 * pinus sylvestris 65500.0 1 PMID:16425030 -6.3.5.4 * populus x xiaohei 66000.0 3 PMID:31035411 -6.3.5.4 * rattus norvegicus 110000.0 3 PMID:23163;PMID:6116467;PMID:6132621 -6.3.5.4 * streptomyces sp. 70000.0 1 * -6.3.5.4 * triticum aestivum 65490.0 2 PMID:29379512 -6.3.5.5 * aquifex aeolicus 171000.0 3 PMID:11574542 -6.3.5.5 * bacillus amyloliquefaciens 120000.0 2 PMID:23750951 -6.3.5.5 * escherichia coli 163000.0 24 PMID:10029528;PMID:10727215;PMID:10843852;PMID:11551199;PMID:12379099;PMID:18220365;PMID:19106093;PMID:19569682;PMID:2658488;PMID:2868386;PMID:9242657;PMID:9361005;PMID:9813025 -6.3.5.5 * geobacillus stearothermophilus 118000.0 2 PMID:10732707;PMID:9370352 -6.3.5.5 * hippoglossus hippoglossus 170000.0 1 PMID:11026664 -6.3.5.5 * methanocaldococcus jannaschii 71000.0 2 PMID:15576558 -6.3.5.5 * pseudomonas aeruginosa 168000.0 3 PMID:6402363 -6.3.5.5 * salmonella enterica subsp. enterica serovar typhimurium 150000.0 3 PMID:211376 -6.3.5.6 * chlamydia trachomatis 55000.0 2 PMID:11585842 -6.3.5.6 * fasciola gigantica 132000.0 1 PMID:29031680 -6.3.5.7 * bacillus subtilis 53500.0 3 PMID:9342321 -6.3.5.7 * chlamydomonas reinhardtii 120000.0 2 PMID:1970821 -6.3.5.7 * homo sapiens 132000.0 3 PMID:19805282 -6.3.5.9 * escherichia coli 45000.0 1 PMID:10966576 -6.3.5.9 * pseudomonas denitrificans (nom. rej.) 97300.0 5 PMID:1917839;PMID:2172209;PMID:2211520 -6.3.5.9 * salmonella enterica subsp. enterica serovar typhimurium 55000.0 4 PMID:15311923;PMID:9822644 -6.4.1.1 * [bacillus] caldotenax 537000.0 2 * -6.4.1.1 * apis mellifera 500000.0 2 * -6.4.1.1 * aquifex aeolicus 70000.0 4 PMID:14993673;PMID:18613815 -6.4.1.1 * arthrobacter globiformis 130000.0 1 PMID:1105579;PMID:851353 -6.4.1.1 * aspergillus nidulans 532000.0 2 PMID:33080172;PMID:6421580 -6.4.1.1 * bacillus sp. (in: firmicutes) 558000.0 2 PMID:476075 -6.4.1.1 * bos taurus 500000.0 2 PMID:1105579 -6.4.1.1 * caenorhabditis elegans 129300.0 1 PMID:11761713 -6.4.1.1 * corynebacterium glutamicum 123000.0 1 PMID:11321586 -6.4.1.1 * emiliania huxleyi 135000.0 1 PMID:22492231 -6.4.1.1 * gallus gallus 500000.0 2 PMID:1105579 -6.4.1.1 * geobacillus thermodenitrificans 501300.0 7 PMID:15030490 -6.4.1.1 * homo sapiens 130000.0 4 PMID:10600533;PMID:1105579;PMID:20807508;PMID:7918683;PMID:851353 -6.4.1.1 * leptosphaeria michotii 440000.0 3 * -6.4.1.1 * meleagris gallopavo 500000.0 2 PMID:1105579 -6.4.1.1 * methanobacterium sp. 70000.0 2 PMID:18613815 -6.4.1.1 * methanocaldococcus jannaschii 480000.0 3 PMID:11195096 -6.4.1.1 * methanococcus sp. 70000.0 2 PMID:18613815 -6.4.1.1 * methanosarcina sp. 70000.0 2 PMID:18613815 -6.4.1.1 * methylobacillus flagellatus 340000.0 1 PMID:27708276 -6.4.1.1 * mycolicibacterium smegmatis 120000.0 1 PMID:10913817 -6.4.1.1 * pseudomonas citronellolis 65000.0 4 PMID:1105579;PMID:6795193 -6.4.1.1 * pseudomonas fluorescens 300000.0 1 PMID:4579 -6.4.1.1 * pseudomonas sp. 70000.0 2 PMID:18613815 -6.4.1.1 * rattus norvegicus 501000.0 4 PMID:1105579;PMID:3178228;PMID:851353 -6.4.1.1 * rhizobium etli 508000.0 3 PMID:20230056;PMID:33080172;PMID:8830693 -6.4.1.1 * rhizopus arrhizus 136750.0 1 PMID:3971971 -6.4.1.1 * saccharomyces cerevisiae 475000.0 3 PMID:1105579;PMID:3042770 -6.4.1.1 * sinorhizobium meliloti 500000.0 2 PMID:11702077 -6.4.1.1 * staphylococcus aureus 260000.0 1 PMID:35943735 -6.4.1.1 * sus scrofa 130000.0 1 PMID:1105579;PMID:851353 -6.4.1.2 * acidianus brierleyi 540000.0 4 PMID:12533469 -6.4.1.2 * anser anser 238000.0 1 PMID:6122424 -6.4.1.2 * arabidopsis sp. 251000.0 1 PMID:7915036 -6.4.1.2 * arabidopsis thaliana 200000.0 1 PMID:15014998 -6.4.1.2 * brassica napus 220000.0 1 PMID:2874090 -6.4.1.2 * cyclotella cryptica 740000.0 2 PMID:16667268 -6.4.1.2 * festuca rubra 240000.0 1 PMID:12859251 -6.4.1.2 * gallus gallus 480000.0 2 PMID:29130 -6.4.1.2 * glycine max 800000.0 7 PMID:10069834;PMID:11454223 -6.4.1.2 * homo sapiens 280000.0 11 PMID:12972648;PMID:14643797;PMID:15749055;PMID:15968460;PMID:16545081;PMID:16854592;PMID:17223360;PMID:21471234;PMID:9099716 -6.4.1.2 * hordeum vulgare 610000.0 6 PMID:12972648;PMID:14643797;PMID:2874090 -6.4.1.2 * lathyrus oleraceus 700000.0 6 PMID:15215578;PMID:6133748;PMID:7957202 -6.4.1.2 * lolium multiflorum 528000.0 3 PMID:12232234 -6.4.1.2 * metallosphaera sedula 560000.0 1 PMID:12581213 -6.4.1.2 * mycosarcoma maydis 880000.0 5 PMID:14766011;PMID:7500941 -6.4.1.2 * myxococcus xanthus 65000.0 3 PMID:10986250 -6.4.1.2 * oryctolagus cuniculus 252000.0 2 PMID:32036;PMID:6116159 -6.4.1.2 * persea americana 650000.0 5 PMID:6146308 -6.4.1.2 * petroselinum crispum 840000.0 5 PMID:6105851;PMID:6133748;PMID:7957202 -6.4.1.2 * rattus norvegicus 10000000.0 13 PMID:11205884;PMID:16545081;PMID:16854592;PMID:235704;PMID:2572585;PMID:2896193;PMID:6116163;PMID:7628470 -6.4.1.2 * rhizobium etli 620000.0 3 PMID:14766918 -6.4.1.2 * ricinus communis 528000.0 1 PMID:6137995 -6.4.1.2 * saccharomyces cerevisiae 250593.0 2 PMID:6116162 -6.4.1.2 * solanum tuberosum 200000.0 1 PMID:15014998 -6.4.1.2 * toxoplasma gondii 240000.0 1 PMID:10557330 -6.4.1.2 * triticum aestivum 700000.0 4 PMID:2874090;PMID:6105851 -6.4.1.2 * xanthomonas citri pv. citri 800000.0 1 PMID:29879157 -6.4.1.2 * yarrowia lipolytica 230000.0 1 PMID:6116163 -6.4.1.2 * zea mays 500000.0 7 PMID:12231704;PMID:12859251;PMID:2874090;PMID:6141767;PMID:7821523 -6.4.1.3 * acidianus brierleyi 540000.0 4 PMID:12533469 -6.4.1.3 * bos taurus 450000.0 5 PMID:16170895;PMID:1769208 -6.4.1.3 * clonorchis sinensis 63400.0 1 PMID:22119288 -6.4.1.3 * homo sapiens 800000.0 6 PMID:11136555;PMID:15890657;PMID:6765947;PMID:7396525 -6.4.1.3 * leptospira interrogans 669000.0 1 PMID:22710261 -6.4.1.3 * metallosphaera sedula 560000.0 3 PMID:12581213 -6.4.1.3 * mycolicibacterium smegmatis 730000.0 4 PMID:447686;PMID:7118926 -6.4.1.3 * myxococcus xanthus 615000.0 3 PMID:9683657 -6.4.1.3 * rattus norvegicus 72000.0 3 PMID:18313395;PMID:19699272 -6.4.1.3 * rhizobium etli 620000.0 3 PMID:14766918 -6.4.1.3 * ruegeria pomeroyi 750000.0 2 PMID:20725044 -6.4.1.3 * sus scrofa 690000.0 1 PMID:13752080 -6.4.1.4 * achromobacter sp. 760000.0 6 PMID:1267 -6.4.1.4 * acidaminococcus fermentans 65000.0 8 PMID:10027965 -6.4.1.4 * arabidopsis thaliana 900000.0 3 PMID:10681539 -6.4.1.4 * bos taurus 835000.0 5 PMID:16170895;PMID:7278687;PMID:7469416;PMID:8161223 -6.4.1.4 * daucus carota 900000.0 3 PMID:10989437 -6.4.1.4 * glycine max 900000.0 3 PMID:10989437 -6.4.1.4 * homo sapiens 80000.0 2 PMID:17360195 -6.4.1.4 * hordeum vulgare 660000.0 3 * -6.4.1.4 * lathyrus oleraceus 530000.0 6 PMID:10989437;PMID:12231881 -6.4.1.4 * pagrus major 76000.0 1 * -6.4.1.4 * pseudomonas aeruginosa 490000.0 2 PMID:16272386;PMID:22805839 -6.4.1.4 * pseudomonas citronellolis 580000.0 5 PMID:7278686;PMID:911753 -6.4.1.4 * rattus norvegicus 72000.0 2 PMID:10693937 -6.4.1.4 * solanum lycopersicum 900000.0 3 PMID:10989437 -6.4.1.4 * solanum tuberosum 500000.0 5 PMID:10989437;PMID:12231881 -6.4.1.4 * xanthomonas citri pv. citri 800000.0 1 PMID:29879157 -6.4.1.4 * zea mays 900000.0 6 PMID:10989437;PMID:7278687;PMID:7469416;PMID:8161223 -6.4.1.5 * pseudomonas aeruginosa 74000.0 2 PMID:18469096 -6.4.1.5 * pseudomonas citronellolis 580000.0 3 PMID:7278686;PMID:911753 -6.4.1.5 * pseudomonas sp. 550000.0 3 PMID:12781773 -6.4.1.5 * zea mays 122000.0 1 PMID:9917324 -6.4.1.6 * cupriavidus metallidurans 388000.0 4 PMID:22492439 -6.4.1.6 * rhodobacter capsulatus 85000.0 2 * -6.4.1.6 * rhodococcus rhodochrous 85000.0 3 PMID:10217764 -6.4.1.6 * xanthobacter autotrophicus 353000.0 7 PMID:12003937 -6.4.1.6 * xanthobacter versatilis 353000.0 7 PMID:10217764;PMID:9237998 -6.4.1.7 * hydrogenobacter thermophilus 998000.0 3 PMID:14731279 -6.4.1.8 * aromatoleum aromaticum 485000.0 7 PMID:20047908 -6.5.1.1 * aeropyrum pernix 70000.0 3 PMID:12935888 -6.5.1.1 * ambystoma mexicanum 160000.0 1 PMID:1497311 -6.5.1.1 * arabidopsis thaliana 87000.0 1 PMID:11442056 -6.5.1.1 * bos taurus 175000.0 10 PMID:1267800;PMID:1695631;PMID:3084491;PMID:4738719;PMID:6802840;PMID:7721901;PMID:9363683;PMID:9539976 -6.5.1.1 * coprinopsis cinerea 90000.0 2 PMID:8647114 -6.5.1.1 * crithidia fasciculata 80000.0 1 PMID:1508676 -6.5.1.1 * drosophila melanogaster 83000.0 2 PMID:3090038 -6.5.1.1 * entamoeba histolytica 75000.0 1 PMID:20603158 -6.5.1.1 * escherichia phage t7 41000.0 1 PMID:8626651 -6.5.1.1 * ferroplasma acidarmanus 67800.0 1 PMID:17136487 -6.5.1.1 * gallus gallus 82000.0 1 PMID:29616 -6.5.1.1 * hemicentrotus pulcherrimus 80000.0 1 PMID:6746596 -6.5.1.1 * homo sapiens 190000.0 4 PMID:4204425;PMID:7357002;PMID:9164481 -6.5.1.1 * hyperthermus butylicus 68000.0 1 PMID:23546841 -6.5.1.1 * lymantria dispar multiple nucleopolyhedrovirus 62000.0 1 PMID:9765460 -6.5.1.1 * mammalia 200000.0 5 PMID:1497311 -6.5.1.1 * methanothermobacter thermautotrophicus 68000.0 1 PMID:10871342 -6.5.1.1 * mus musculus 240000.0 5 PMID:21390131;PMID:2340590;PMID:6746618 -6.5.1.1 * neisseria meningitidis 32000.0 4 PMID:14730975 -6.5.1.1 * orthopoxvirus vaccinia 61000.0 1 PMID:1497311 -6.5.1.1 * pleurodeles sp. 180000.0 1 PMID:1497311 -6.5.1.1 * rattus norvegicus 130000.0 4 PMID:1267800;PMID:1730240;PMID:2383569;PMID:3803389;PMID:7721901 -6.5.1.1 * saccharolobus shibatae 67647.0 2 PMID:12486455 -6.5.1.1 * saccharomyces cerevisiae 104000.0 4 PMID:1445910;PMID:2204827;PMID:9837999 -6.5.1.1 * schizosaccharomyces pombe 86000.0 1 PMID:2204827 -6.5.1.1 * tequatrovirus t4 68000.0 2 PMID:19082974 -6.5.1.1 * thermococcus kodakarensis 64079.0 2 PMID:11053387 -6.5.1.1 * thermococcus sp. 63000.0 1 * -6.5.1.1 * xenopus laevis 180000.0 1 PMID:2017356 -6.5.1.2 * aquifex pyrophilus 82000.0 1 PMID:11453459 -6.5.1.2 * betaentomopoxvirus amoorei 62000.0 1 PMID:11459847 -6.5.1.2 * escherichia coli 77000.0 4 PMID:10497258;PMID:18515356;PMID:19082974 -6.5.1.2 * geobacillus stearothermophilus 36000.0 4 PMID:9878389 -6.5.1.2 * helicobacter pylori 80000.0 1 PMID:9414650 -6.5.1.2 * mimivirus 70000.0 1 PMID:16844179 -6.5.1.2 * pseudoalteromonas haloplanktis 74590.0 2 PMID:10848966 -6.5.1.2 * rhodothermus marinus 79487.0 1 PMID:7642120 -6.5.1.2 * staphylococcus aureus 75290.0 2 PMID:11325928;PMID:19923722 -6.5.1.2 * streptococcus pneumoniae 72130.0 2 PMID:18795946 -6.5.1.2 * thermotoga maritima 78000.0 1 * -6.5.1.2 * thermus filiformis 75940.0 1 PMID:10698952 -6.5.1.2 * thermus thermophilus 80400.0 2 PMID:6469954 -6.5.1.2 * wolbachia endosymbiont of brugia malayi 75000.0 1 PMID:22815933 -6.5.1.3 * methanothermobacter thermautotrophicus 45000.0 1 PMID:18829718 -6.5.1.3 * naegleria gruberi 38000.0 1 PMID:25740837 -6.5.1.3 * rhodothermus phage rm378 51300.0 1 PMID:14654700 -6.5.1.3 * tequatrovirus t4 52000.0 6 PMID:10712602;PMID:12228725;PMID:19082974;PMID:219895;PMID:4342972;PMID:938049 -6.5.1.3 * trypanosoma brucei 52000.0 3 PMID:11233974;PMID:12052873 -6.5.1.3 * vibrio phage kvp40 42000.0 1 PMID:14967495 -6.5.1.4 * homo sapiens 40000.0 4 PMID:10397337;PMID:19478432;PMID:19690099;PMID:2199762;PMID:2581947;PMID:3416880 -6.5.1.4 * saccharomyces cerevisiae 40000.0 1 PMID:10790377 -6.5.1.4 * sulfurisphaera tokodaii 40000.0 1 PMID:10397337;PMID:19478432 -6.5.1.5 * pyrococcus furiosus 37000.0 1 PMID:22074260 -6.5.1.6 * thermococcus onnurineus 63000.0 1 PMID:16614906 -6.5.1.7 * hyperthermus butylicus 68000.0 1 PMID:23546841 -6.5.1.7 * sulfophobococcus zilligii 70000.0 1 PMID:18647334 -6.5.1.8 * escherichia coli 45000.0 1 PMID:21224389 -6.5.1.8 * homo sapiens 55000.0 1 PMID:28093457 -6.5.1.8 * methanopyrus kandleri 55000.0 1 PMID:21209330 -6.5.1.8 * myxococcus xanthus 48000.0 2 PMID:26350128 -6.5.1.8 * pyrobaculum aerophilum 55000.0 1 PMID:21209330 -6.5.1.8 * pyrococcus horikoshii 55000.0 1 PMID:21209330 -6.5.1.9 * methanothermobacter thermautotrophicus 150000.0 1 * -6.5.1.9 * methanothermus fervidus 145000.0 2 PMID:2226838;PMID:9811660 -6.6.1.1 * arabidopsis thaliana 150000.0 5 PMID:11842180;PMID:19605356;PMID:7575622;PMID:9359397 -6.6.1.1 * cereibacter sphaeroides 140000.0 5 PMID:11478896;PMID:8631364;PMID:9359397 -6.6.1.1 * glycine max 153491.0 3 PMID:7575622;PMID:9359397;PMID:9588025 -6.6.1.1 * hordeum vulgare 140000.0 3 PMID:15153108 -6.6.1.1 * lathyrus oleraceus 150000.0 3 PMID:19605356 -6.6.1.1 * nicotiana tabacum 82900.0 1 PMID:9418040 -6.6.1.1 * prosthecochloris vibrioformis 42000.0 2 PMID:9457877 -6.6.1.1 * rhodobacter capsulatus 140000.0 4 PMID:16928192;PMID:9359397 -6.6.1.1 * synechocystis sp. 148000.0 5 PMID:11478896;PMID:21110975;PMID:9359397 -6.6.1.1 * thermosynechococcus vestitus 148000.0 1 PMID:22179610 -6.6.1.2 * pseudomonas denitrificans (nom. rej.) 258000.0 4 PMID:1429466 -7.1.1.1 * bos taurus 278000.0 10 PMID:26313;PMID:3277960;PMID:3426231;PMID:3662533;PMID:409434;PMID:6863266;PMID:7213674;PMID:8102370;PMID:921770 -7.1.1.1 * cereibacter sphaeroides 6784.0 1 PMID:4150340 -7.1.1.1 * entamoeba histolytica 155000.0 6 PMID:11163794;PMID:12004068;PMID:20382757 -7.1.1.1 * escherichia coli 54000.0 12 PMID:10773166;PMID:1838340;PMID:3525165;PMID:3884596;PMID:3891338;PMID:8112317 -7.1.1.1 * homo sapiens 110000.0 1 PMID:20388492 -7.1.1.1 * klebsiella pneumoniae 54000.0 1 PMID:8117298 -7.1.1.1 * mammalia 196000.0 1 PMID:1838340 -7.1.1.1 * rattus norvegicus 111500.0 2 PMID:3277960;PMID:3662533 -7.1.1.1 * rhodobacter capsulatus 53000.0 2 PMID:1849819 -7.1.1.1 * rhodospirillum rubrum 84000.0 5 PMID:16533815;PMID:17911104;PMID:9398076 -7.1.1.10 * synechocystis sp. pcc 6803 490000.0 2 PMID:15548534 -7.1.1.10 * thermosynechococcus vestitus 500000.0 2 PMID:15910282;PMID:25630976 -7.1.1.12 * bacillus licheniformis 113000.0 1 PMID:17154542 -7.1.1.2 * acidianus ambivalens 60000.0 3 PMID:11460922;PMID:16303338 -7.1.1.2 * agrobacterium tumefaciens 46000.0 1 PMID:16884501 -7.1.1.2 * aquifex aeolicus 550000.0 2 PMID:11852056;PMID:12627969 -7.1.1.2 * bos taurus 980000.0 3 PMID:14756315;PMID:16150735;PMID:16388600;PMID:35108 -7.1.1.2 * caenorhabditis elegans 950000.0 3 PMID:16443191;PMID:17706937 -7.1.1.2 * corynebacterium glutamicum 55000.0 2 PMID:11731134;PMID:15665480 -7.1.1.2 * cyberlindnera jadinii 87000.0 2 * -7.1.1.2 * escherichia coli 600000.0 6 PMID:12637579;PMID:14970214;PMID:15922336;PMID:2118386;PMID:23543743 -7.1.1.2 * methylococcus capsulatus 36000.0 1 PMID:11811946 -7.1.1.2 * mus musculus 700000.0 36 PMID:15591592 -7.1.1.2 * mycobacterium tuberculosis 50000.0 1 PMID:16469750 -7.1.1.2 * neomoorella thermoacetica 210000.0 3 PMID:8774714 -7.1.1.2 * neurospora crassa 610000.0 2 PMID:14741584;PMID:2956429 -7.1.1.2 * polytomella sp. pringsheim 198.80 980000.0 1 PMID:14756315;PMID:16388600 -7.1.1.2 * rattus norvegicus 700000.0 37 PMID:11875069;PMID:15591592 -7.1.1.2 * saccharomyces cerevisiae 53000.0 1 PMID:11370674;PMID:3138118 -7.1.1.2 * solanum tuberosum 900000.0 1 PMID:8294484 -7.1.1.2 * sulfolobus acidocaldarius 95000.0 2 PMID:2822684 -7.1.1.2 * trypanosoma brucei 65000.0 2 PMID:11863445 -7.1.1.2 * zea mays 550000.0 7 PMID:15943805 -7.1.1.3 * escherichia coli 320000.0 5 PMID:1322173;PMID:24681096 -7.1.1.3 * vibrio alginolyticus 79000.0 3 PMID:8443214 -7.1.1.4 * acidianus ambivalens 149000.0 4 PMID:9023221 -7.1.1.4 * aeropyrum pernix 47000.0 3 PMID:12471503 -7.1.1.4 * ferroplasma acidiphilum 850000.0 1 PMID:25896560 -7.1.1.4 * sulfolobus acidocaldarius 570000.0 10 PMID:12530544;PMID:2166661;PMID:7984110;PMID:8076636;PMID:9079667 -7.1.1.5 * bacillus subtilis 144000.0 11 PMID:7575098;PMID:8394685 -7.1.1.5 * thermoplasma acidophilum 150000.0 1 PMID:1879426 -7.1.1.6 * chlamydomonas reinhardtii 310000.0 2 PMID:9268322 -7.1.1.6 * cyanobacterium sp. 220000.0 1 PMID:17076484;PMID:19689132 -7.1.1.6 * mastigocladus laminosus 217100.0 5 PMID:12438564;PMID:20960122 -7.1.1.6 * nostoc sp. 214200.0 1 PMID:20960122 -7.1.1.6 * spinacia oleracea 286500.0 13 PMID:12438564;PMID:17076484;PMID:19689132;PMID:20960122;PMID:2826246;PMID:3813555;PMID:6269845;PMID:6307358;PMID:9222311 -7.1.1.7 * escherichia coli 145000.0 3 PMID:3281937 -7.1.1.8 * bos taurus 640000.0 122 PMID:213674;PMID:213694;PMID:213695;PMID:2164842;PMID:2856130;PMID:2996928;PMID:3008590;PMID:3009231;PMID:3009460;PMID:3017970;PMID:3036596;PMID:459885;PMID:597492;PMID:6126477;PMID:6267990;PMID:6307358;PMID:6311535;PMID:6321316;PMID:7120390;PMID:788795;PMID:8592474 -7.1.1.8 * cereibacter sphaeroides 200000.0 24 PMID:10092497;PMID:2161250;PMID:6290210;PMID:6295373;PMID:6307358;PMID:6325447 -7.1.1.8 * homo sapiens 48960.0 10 PMID:2856130;PMID:3009231;PMID:8592474;PMID:8988236 -7.1.1.8 * neurospora crassa 550000.0 47 PMID:213696;PMID:226365;PMID:2856127;PMID:2856130;PMID:6267990;PMID:6307358;PMID:6311535;PMID:6321316 -7.1.1.8 * paracoccus denitrificans 121000.0 5 PMID:3017970 -7.1.1.8 * rattus norvegicus 480000.0 2 PMID:12794875 -7.1.1.8 * rhodobacter capsulatus 44000.0 3 PMID:8383528 -7.1.1.8 * rhodospirillum rubrum 88400.0 4 PMID:2548618 -7.1.1.8 * saccharomyces cerevisiae 50240.0 30 PMID:179821;PMID:213674;PMID:2856130;PMID:2981208;PMID:3023384;PMID:3028797;PMID:597492;PMID:6307358;PMID:6311535;PMID:6323264 -7.1.1.8 * spinacia oleracea 23000.0 6 PMID:6307358 -7.1.1.8 * trichormus variabilis 22500.0 4 PMID:6307358 -7.1.1.9 * ancylobacter novellus 115000.0 5 PMID:6248108;PMID:6263325 -7.1.1.9 * arabidopsis thaliana 12724.0 2 PMID:16782050 -7.1.1.9 * bacillus sp. ps3 250000.0 7 PMID:3030415;PMID:6087899;PMID:6311261 -7.1.1.9 * bacillus subtilis 315000.0 10 PMID:2536327;PMID:2856123;PMID:3038545;PMID:6299734;PMID:7619069 -7.1.1.9 * bos taurus 350000.0 16 PMID:2178268;PMID:2821746;PMID:3021525;PMID:31533957;PMID:6264952;PMID:6274682;PMID:6301544;PMID:6307356 -7.1.1.9 * cereibacter sphaeroides 45000.0 6 PMID:2856120;PMID:6286309;PMID:6311261 -7.1.1.9 * cytobacillus firmus 56000.0 3 PMID:6327654 -7.1.1.9 * dictyostelium discoideum 55000.0 6 * -7.1.1.9 * erythrobacter longus 116000.0 3 PMID:2830243 -7.1.1.9 * eukaryota 280000.0 1 PMID:38840 -7.1.1.9 * geobacillus stearothermophilus 57000.0 3 PMID:2536327;PMID:2856123 -7.1.1.9 * geobacillus thermodenitrificans 60371.0 3 PMID:20226371 -7.1.1.9 * gobiocypris rarus 56400.0 1 PMID:17364807 -7.1.1.9 * helicobacter pylori 200000.0 3 PMID:9880817 -7.1.1.9 * homo sapiens 43600.0 7 PMID:16782050;PMID:6264952 -7.1.1.9 * ipomoea batatas 162000.0 6 PMID:27143 -7.1.1.9 * mammalia 210000.0 1 PMID:6307356 -7.1.1.9 * methylobacillus flagellatus kt 170000.0 1 * -7.1.1.9 * micrococcus luteus 54000.0 5 PMID:2821914 -7.1.1.9 * mus musculus 35000.0 3 PMID:18583456 -7.1.1.9 * neurospora crassa 40000.0 7 PMID:6267990 -7.1.1.9 * nitrobacter winogradskyi 51000.0 4 PMID:2856189;PMID:6260762 -7.1.1.9 * nitrosomonas europaea 83000.0 8 PMID:2542236 -7.1.1.9 * paracoccus denitrificans 86000.0 6 PMID:2832167;PMID:6263325 -7.1.1.9 * paramagnetospirillum magnetotacticum 43000.0 3 PMID:8013655 -7.1.1.9 * pseudomonas aeruginosa 82000.0 8 PMID:1328171;PMID:6281067 -7.1.1.9 * pseudomonas sp. 79000.0 5 PMID:2999096 -7.1.1.9 * rhodobacter capsulatus 65000.0 1 * -7.1.1.9 * rhodopseudomonas palustris 30500.0 4 PMID:9286 -7.1.1.9 * saccharomyces cerevisiae 226000.0 11 PMID:3021525;PMID:4346952;PMID:4351218 -7.1.1.9 * sphyrna lewini 158000.0 8 PMID:6244291;PMID:6301544 -7.1.1.9 * squalus acanthias 158000.0 6 PMID:6244291 -7.1.1.9 * streptomyces viridochromogenes 90000.0 1 PMID:25778839 -7.1.1.9 * stutzerimonas stutzeri 190000.0 9 PMID:11707262;PMID:24214947 -7.1.1.9 * sus scrofa 204000.0 1 PMID:2856135 -7.1.1.9 * synechococcus elongatus pcc 7942 = fachb-805 55000.0 4 PMID:2545245 -7.1.1.9 * thermus thermophilus 71000.0 9 PMID:2540968;PMID:3030415;PMID:6244539;PMID:6244813 -7.1.1.9 * trichormus variabilis 36000.0 1 * -7.1.2.1 * arabidopsis thaliana 96000.0 1 PMID:9473454 -7.1.2.1 * beta vulgaris 600000.0 2 PMID:2142002;PMID:22257033;PMID:23399403 -7.1.2.1 * brassica napus 100000.0 1 PMID:2142002;PMID:22257033;PMID:23399403 -7.1.2.1 * camelina sativa 100000.0 1 PMID:2142002;PMID:22257033;PMID:23399403 -7.1.2.1 * cucumis sativus 120000.0 3 PMID:21638005 -7.1.2.1 * hevea brasiliensis 106100.0 3 * -7.1.2.1 * homo sapiens 48500.0 2 PMID:20669186 -7.1.2.1 * hordeum vulgare subsp. vulgare 100000.0 1 PMID:2142002;PMID:22257033;PMID:23399403 -7.1.2.1 * marchantia polymorpha 95000.0 4 PMID:20516032;PMID:22496511 -7.1.2.1 * neurospora crassa 105000.0 1 PMID:18997787;PMID:6446934 -7.1.2.1 * petunia x hybrida 105000.0 1 PMID:18997787;PMID:6446934 -7.1.2.1 * phytophthora nicotianae 116300.0 1 PMID:16730200 -7.1.2.1 * saccharomyces cerevisiae 100000.0 1 PMID:29744292 -7.1.2.1 * suaeda salsa 66000.0 4 PMID:20377691 -7.1.2.1 * trypanosoma brucei 100600.0 3 PMID:16757482 -7.1.2.1 * vicia faba 95000.0 1 PMID:20516032;PMID:22496511 -7.1.2.2 * aedes albopictus 62800.0 1 PMID:17321148 -7.1.2.2 * alcaligenes faecalis 300000.0 1 * -7.1.2.2 * avena sativa 650000.0 1 PMID:16669020 -7.1.2.2 * bos taurus 347000.0 7 PMID:20412062;PMID:4273937 -7.1.2.2 * cereibacter sphaeroides 300000.0 1 * -7.1.2.2 * enterococcus faecalis 385000.0 3 * -7.1.2.2 * escherichia coli 400000.0 1 * -7.1.2.2 * gallus gallus 66000.0 5 PMID:1451435 -7.1.2.2 * geobacillus stearothermophilus 280000.0 1 * -7.1.2.2 * haloferax volcanii 70000.0 5 PMID:9045643 -7.1.2.2 * phycomyces blakesleeanus 390000.0 6 PMID:1838928 -7.1.2.2 * priestia megaterium 379000.0 3 PMID:2894831 -7.1.2.2 * pyrococcus horikoshii 66000.0 2 PMID:15272184;PMID:16508090 -7.1.2.2 * rattus norvegicus 384000.0 1 * -7.1.2.2 * saccharomyces cerevisiae 360000.0 2 PMID:20412062 -7.1.2.2 * spinacia oleracea 325000.0 6 PMID:136996 -7.1.2.2 * sulfolobus acidocaldarius 51526.0 1 PMID:2903160 -7.1.2.2 * sulfurisphaera tokodaii 66009.0 1 PMID:2896191 -7.1.2.2 * thermosynechococcus vestitus 54271.0 7 PMID:18206981 -7.1.3.1 * ascaris suum 40600.0 3 PMID:12823552 -7.1.3.1 * escherichia coli 71000.0 2 PMID:14670604;PMID:15178477 -7.1.3.1 * periplaneta americana 65000.0 1 PMID:19111615 -7.1.3.1 * rhodospirillum rubrum 60000.0 1 PMID:14670604;PMID:15178477 -7.1.3.1 * sesamum indicum 21900.0 3 PMID:11989717 -7.1.3.1 * toxoplasma gondii 85000.0 2 PMID:12411435 -7.1.3.1 * trypanosoma brucei 47300.0 1 PMID:14615483 -7.1.3.1 * vigna radiata 158000.0 4 PMID:11113147;PMID:15178470;PMID:2161215 -7.2.1.1 * vibrio alginolyticus 254000.0 16 PMID:7805867;PMID:9490015 -7.2.1.1 * vibrio cholerae serotype o1 360000.0 14 PMID:11248234;PMID:11888296;PMID:18454933;PMID:20558724;PMID:21885438 -7.2.1.1 * vibrio harveyi 48400.0 12 PMID:15807651;PMID:20056102 -7.2.1.2 * acetobacterium woodii 36600.0 5 PMID:19222539 -7.2.1.2 * thermotoga maritima 290000.0 6 PMID:32770029;PMID:33342435 -7.2.1.2 * vibrio cholerae serotype o1 39000.0 2 PMID:18831535 -7.2.1.3 * mus musculus 31500.0 3 PMID:16911521 -7.2.1.3 * oryctolagus cuniculus 33000.0 1 PMID:11846393 -7.2.1.3 * schistosoma japonicum 30000.0 2 PMID:21103361 -7.2.1.4 * methanosarcina acetivorans 69000.0 1 PMID:22636775 -7.2.1.4 * methanosarcina mazei 380000.0 7 PMID:8774736 -7.2.1.4 * methanothermobacter marburgensis 670000.0 6 PMID:11248186;PMID:27342374;PMID:7813469;PMID:8001564;PMID:8477726 -7.2.1.4 * methanothermobacter thermautotrophicus 900000.0 2 PMID:1737047 -7.2.2.1 * acetobacterium woodii 590000.0 12 PMID:11248193;PMID:30791207;PMID:8033902 -7.2.2.1 * alkalithermobacter thermoalcaliphilus 60000.0 9 PMID:16816177 -7.2.2.1 * caloramator fervidus 72300.0 16 PMID:16967304 -7.2.2.1 * dunaliella maritima 400000.0 2 PMID:7706221 -7.2.2.1 * enterococcus hirae 500000.0 44 PMID:10340844;PMID:11248190;PMID:16691474;PMID:7706221;PMID:8157629;PMID:9312089 -7.2.2.1 * methanothermobacter thermautotrophicus 400000.0 1 PMID:7672109 -7.2.2.1 * tetraselmis viridis 400000.0 2 PMID:7706221 -7.2.2.1 * thermococcus onnurineus 670000.0 1 PMID:25593316 -7.2.2.10 * arabidopsis thaliana 115000.0 2 PMID:21073872;PMID:23974359 -7.2.2.10 * bos taurus 115000.0 2 PMID:16278046;PMID:22387132 -7.2.2.10 * candida albicans 140000.0 1 PMID:23731904 -7.2.2.10 * canis lupus familiaris 150000.0 1 PMID:6451626 -7.2.2.10 * carassius carassius 110000.0 2 PMID:23239195 -7.2.2.10 * eriocheir sinensis 109600.0 1 * -7.2.2.10 * homo sapiens 138000.0 4 PMID:18947868;PMID:6218823 -7.2.2.10 * lota lota 110000.0 1 PMID:23239195 -7.2.2.10 * mus musculus 133000.0 3 PMID:18599310;PMID:23699388 -7.2.2.10 * oryctolagus cuniculus 110000.0 2 PMID:22387132;PMID:23331704 -7.2.2.10 * paramecium tetraurelia 114700.0 2 PMID:9693098 -7.2.2.10 * plasmodium falciparum 139000.0 1 PMID:23497141 -7.2.2.10 * procambarus clarkii 130000.0 1 PMID:15277554 -7.2.2.10 * rattus norvegicus 135000.0 3 PMID:20660595;PMID:22240025 -7.2.2.10 * solanum lycopersicum 72000.0 1 PMID:23974359 -7.2.2.10 * sus scrofa 103000.0 2 PMID:22240025 -7.2.2.10 * trachemys scripta elegans 120000.0 1 PMID:20008357 -7.2.2.12 * arabidopsis halleri 70000.0 1 PMID:28588597 -7.2.2.12 * escherichia coli 160000.0 7 PMID:10529259;PMID:10995032;PMID:11412123;PMID:12746428;PMID:16890908 -7.2.2.12 * noccaea caerulescens 128000.0 5 PMID:17826738;PMID:21621506;PMID:28588597 -7.2.2.12 * streptococcus pyogenes 36000.0 1 PMID:10564500 -7.2.2.13 * aquarana catesbeiana 110000.0 1 PMID:16165176 -7.2.2.13 * bos taurus 155000.0 6 PMID:19101784;PMID:22284223;PMID:22827367 -7.2.2.13 * camelus dromedarius 112696.0 1 PMID:35235155 -7.2.2.13 * electrophorus electricus 110000.0 1 PMID:25793901 -7.2.2.13 * goniopsis cruentata 115000.0 1 PMID:32440867 -7.2.2.13 * macrobrachium nipponense 112290.0 1 PMID:30784852 -7.2.2.13 * macrobrachium rosenbergii 108000.0 1 PMID:23784064 -7.2.2.13 * mammalia 380000.0 7 PMID:16139683;PMID:224922;PMID:2835594 -7.2.2.13 * monopterus albus 113000.0 1 PMID:24391932 -7.2.2.13 * rattus norvegicus 110000.0 4 PMID:15975899;PMID:16488623 -7.2.2.13 * rhinella marina 110000.0 2 PMID:15774534 -7.2.2.13 * schistosoma mansoni 111817.0 1 PMID:11578091 -7.2.2.13 * shark 379000.0 1 PMID:2835594 -7.2.2.13 * xiphopenaeus kroyeri 110000.0 1 PMID:25534346 -7.2.2.14 * arabidopsis thaliana 42000.0 1 PMID:16720382 -7.2.2.14 * escherichia coli 132000.0 4 PMID:16720382;PMID:16835234 -7.2.2.14 * gallus gallus 37000.0 1 PMID:21627970 -7.2.2.14 * methanocaldococcus jannaschii 42000.0 1 PMID:16720382 -7.2.2.14 * rattus norvegicus 105000.0 1 PMID:1444468 -7.2.2.14 * salmonella enterica subsp. enterica serovar typhimurium 102000.0 8 PMID:1328179;PMID:16720382;PMID:1824701;PMID:7751273;PMID:7883724;PMID:8314774;PMID:9622348;PMID:9673265 -7.2.2.14 * thermotoga maritima 42000.0 1 PMID:16720382 -7.2.2.16 * escherichia coli 45000.0 7 PMID:2549374;PMID:2823072 -7.2.2.16 * staphylococcus aureus 36100.0 3 PMID:10913070 -7.2.2.18 * escherichia coli 35370.0 6 PMID:2651410 -7.2.2.19 * cavia porcellus 500000.0 2 PMID:20122893 -7.2.2.19 * homo sapiens 115000.0 5 PMID:15135233;PMID:25347460;PMID:25993003 -7.2.2.19 * oryctolagus cuniculus 95000.0 3 PMID:11368180;PMID:25301939;PMID:8279517 -7.2.2.19 * rattus norvegicus 35000.0 2 PMID:17071328;PMID:2165052 -7.2.2.19 * sus scrofa 270000.0 3 PMID:1314570;PMID:23055529;PMID:26952080 -7.2.2.2 * arabidopsis thaliana 70000.0 1 PMID:18390807 -7.2.2.2 * drosophila melanogaster 97900.0 1 PMID:19001374 -7.2.2.2 * listeria monocytogenes 77000.0 1 PMID:11602255 -7.2.2.2 * saccharomyces cerevisiae 171000.0 7 PMID:10753671;PMID:7521334;PMID:9837923 -7.2.2.2 * schizosaccharomyces pombe 200000.0 1 PMID:1396551 -7.2.2.21 * bacillus subtilis 70000.0 1 PMID:1530844 -7.2.2.21 * enterobacter sp. 76000.0 1 PMID:23344939 -7.2.2.3 * acetobacterium woodii 57000.0 5 PMID:8033902 -7.2.2.3 * aphanothece halophytica 56000.0 7 PMID:20691102 -7.2.2.3 * caloramator fervidus 66000.0 6 PMID:9023212 -7.2.2.3 * cavia porcellus 113000.0 3 PMID:21334305 -7.2.2.3 * enterococcus hirae 400000.0 15 PMID:10340844;PMID:7706221;PMID:9312089 -7.2.2.3 * exiguobacterium aurantiacum 100000.0 2 PMID:15715958 -7.2.2.3 * ilyobacter tartaricus 56000.0 5 PMID:9642181 -7.2.2.3 * leishmania donovani 115500.0 1 PMID:12831521 -7.2.2.3 * methanothermobacter thermautotrophicus 400000.0 1 PMID:7672109 -7.2.2.3 * millerozyma farinosa 123000.0 1 PMID:15075266 -7.2.2.3 * mycosarcoma maydis 123500.0 2 PMID:15075266 -7.2.2.3 * trypanosoma brucei 150000.0 1 PMID:12831521 -7.2.2.3 * trypanosoma cruzi 120000.0 1 PMID:16797482 -7.2.2.5 * synechocystis sp. 36100.0 3 PMID:8824246 -7.2.2.6 * alicyclobacillus acidocaldarius 79000.0 3 PMID:2527329;PMID:2849541 -7.2.2.6 * cereibacter sphaeroides 137000.0 4 PMID:1400242 -7.2.2.6 * escherichia coli 350000.0 24 PMID:10026265;PMID:16953591;PMID:18298081;PMID:2527329;PMID:2849541;PMID:6144601;PMID:8499455;PMID:8672505;PMID:8914982 -7.2.2.6 * flabellia petiolata 129500.0 1 PMID:16167182 -7.2.2.6 * pyropia yezoensis 128400.0 1 PMID:16167182 -7.2.2.6 * pythium aphanidermatum 122200.0 1 PMID:16167182 -7.2.2.7 * haemophilus influenzae 34000.0 1 PMID:18461372 -7.2.2.7 * neisseria gonorrhoeae 34000.0 1 PMID:18461372 -7.2.2.7 * neisseria meningitidis 34000.0 1 PMID:18461372 -7.2.2.7 * staphylococcus aureus 40000.0 2 PMID:9673260 -7.2.2.7 * staphylococcus epidermidis 32000.0 1 PMID:9673260 -7.2.2.8 * aquifex aeolicus 80000.0 2 PMID:18374940 -7.2.2.8 * homo sapiens 480000.0 3 PMID:19520855;PMID:28842499 -7.2.2.8 * mycobacterium tuberculosis 77500.0 1 PMID:32054527 -7.2.2.8 * thermotoga maritima 83300.0 1 PMID:17616523 -7.2.2.9 * aquifex aeolicus 80000.0 2 PMID:18374940 -7.2.2.9 * drosophila melanogaster 150000.0 1 PMID:20372979 -7.2.2.9 * homo sapiens 195000.0 6 PMID:19679821;PMID:19922814;PMID:20032459;PMID:21454443 -7.2.2.9 * plasmodium falciparum 298600.0 1 PMID:15125686 -7.2.2.9 * rattus norvegicus 97000.0 2 PMID:19679821 -7.2.2.9 * saccharomyces cerevisiae 110000.0 1 PMID:21163943 -7.2.4.1 * malonomonas rubra 43023.0 1 PMID:9128730 -7.2.4.1 * propionigenium modestum 41200.0 1 PMID:9428714 -7.2.4.2 * klebsiella aerogenes 65000.0 3 PMID:3520232;PMID:6418543 -7.2.4.2 * klebsiella pneumoniae 63600.0 3 PMID:2454915 -7.2.4.2 * salmonella enterica subsp. enterica serovar typhimurium 300000.0 6 PMID:2556085;PMID:32459174 -7.2.4.3 * propionigenium modestum 56100.0 8 PMID:9428714 -7.2.4.3 * veillonella parvula 300000.0 5 PMID:5686595;PMID:6852015 -7.2.4.4 * malonomonas rubra 67000.0 2 PMID:18251085;PMID:8664258 -7.2.4.5 * [clostridium] symbiosum 232000.0 5 PMID:19654317 -7.2.4.5 * acidaminococcus fermentans 120000.0 12 PMID:10027965;PMID:2422027;PMID:6628393 -7.2.4.5 * fusobacterium nucleatum 65000.0 4 PMID:2244788 -7.2.4.5 * pseudomonas sp. 170000.0 2 PMID:8439237 -7.3.2.1 * arabidopsis thaliana 100000.0 8 PMID:18353780;PMID:20565143;PMID:21960139;PMID:22645553;PMID:26342016 -7.3.2.1 * chrysanthemum x morifolium 57970.0 1 PMID:24411021 -7.3.2.1 * escherichia coli 30000.0 1 PMID:8682808 -7.3.2.1 * mycobacterium tuberculosis 69300.0 3 PMID:11567022;PMID:12842040 -7.3.2.1 * pseudomonas aeruginosa 56000.0 1 PMID:19184417 -7.3.2.1 * saccharomyces cerevisiae 98000.0 1 PMID:19590579 -7.3.2.1 * serendipita indica 57700.0 1 PMID:20479005 -7.3.2.1 * zea mays 60600.0 6 PMID:16547863 -7.3.2.4 * arabidopsis thaliana 61099.0 6 PMID:17583518;PMID:17993627;PMID:20561257;PMID:26058834 -7.3.2.4 * leptolyngbya laminosa 45000.0 4 PMID:16442736 -7.3.2.4 * pseudomonas aeruginosa 50600.0 2 * -7.3.2.5 * bradyrhizobium japonicum 24500.0 3 PMID:16385130 -7.3.2.5 * oleidesulfovibrio alaskensis 29000.0 1 PMID:24992597 -7.3.2.5 * peptoclostridium acidaminophilum 48000.0 2 PMID:14624334 -7.3.2.6 * oleidesulfovibrio alaskensis 29000.0 1 PMID:24992597 -7.3.2.6 * pyrococcus furiosus 40000.0 1 PMID:16952940 -7.3.2.7 * escherichia coli 63000.0 2 PMID:18230343;PMID:20000479 -7.4.2.1 * lactococcus lactis 49600.0 1 PMID:16621821 -7.4.2.10 * saccharomyces cerevisiae 150000.0 1 PMID:12044871 -7.4.2.13 * clostridioides difficile 36970.0 2 PMID:29867812 -7.4.2.3 * homo sapiens 86000.0 3 PMID:17596514;PMID:18632665 -7.4.2.3 * saccharomyces cerevisiae 58000.0 4 PMID:14605210;PMID:14638855;PMID:15955075 -7.4.2.4 * arabidopsis thaliana 200000.0 2 PMID:22521451 -7.4.2.4 * lathyrus oleraceus 230000.0 7 PMID:10961945;PMID:18263621;PMID:7989297;PMID:8567731 -7.4.2.4 * spinacia oleracea 117000.0 1 PMID:7629156 -7.4.2.5 * bacillus subtilis 50200.0 2 PMID:8085823 -7.4.2.5 * bacteria 102000.0 1 PMID:17964601 -7.4.2.5 * escherichia coli 204000.0 3 PMID:18602400;PMID:18978043;PMID:8453066 -7.4.2.5 * homo sapiens 72000.0 6 PMID:16864587;PMID:17977821;PMID:18434309;PMID:20377823 -7.4.2.5 * lactococcus lactis 34400.0 3 PMID:9361411 -7.4.2.5 * mus musculus 17100.0 1 PMID:26320580 -7.4.2.5 * pseudomonas aeruginosa 102000.0 1 PMID:16427308 -7.4.2.5 * rattus norvegicus 72000.0 3 PMID:16624807;PMID:26320580 -7.4.2.5 * saccharomyces cerevisiae 66000.0 2 PMID:12746444 -7.4.2.5 * streptococcus parasanguinis 92000.0 4 PMID:16999826 -7.4.2.6 * bacillus subtilis 60000.0 1 PMID:15588833 -7.4.2.6 * borreliella burgdorferi 62400.0 5 PMID:14679224 -7.4.2.6 * ligilactobacillus salivarius 61700.0 2 PMID:25998246 -7.4.2.6 * moraxella catarrhalis 36300.0 2 PMID:25156736 -7.4.2.6 * staphylococcus aureus 59000.0 1 PMID:17496096 -7.4.2.6 * thermococcus kodakarensis 97000.0 1 * -7.4.2.6 * thermotoga maritima 73.0 1 PMID:27377296 -7.4.2.6 * xanthomonas axonopodis 59900.0 3 PMID:15060731 -7.4.2.7 * saccharomyces cerevisiae 145000.0 1 PMID:8095825 -7.4.2.8 * chlamydia pneumoniae 48100.0 2 PMID:18708502;PMID:20096108 -7.4.2.8 * enterococcus faecalis 60000.0 1 PMID:18326569 -7.4.2.8 * escherichia coli 622000.0 11 PMID:17704542;PMID:17964526;PMID:18065528;PMID:18487341;PMID:23523349 -7.4.2.8 * legionella pneumophila 256700.0 1 PMID:29770512 -7.4.2.8 * mycobacterium tuberculosis 106000.0 2 PMID:18487341 -7.4.2.8 * myxococcus xanthus 63800.0 6 PMID:18223089 -7.4.2.8 * pseudomonas syringae 3500000.0 4 PMID:12734178 -7.4.2.8 * salmonella enterica 290000.0 2 PMID:15060043 -7.4.2.8 * salmonella enterica subsp. enterica serovar typhimurium 50000.0 1 PMID:18216858 -7.4.2.8 * thermus thermophilus 615000.0 1 PMID:29464394 -7.4.2.8 * vibrio cholerae 56000.0 1 PMID:23954505 -7.4.2.8 * vibrio vulnificus 250000.0 2 PMID:25092625 -7.4.2.8 * yersinia enterocolitica 603000.0 2 PMID:24124464 -7.4.2.8 * yersinia pseudotuberculosis 48000.0 1 PMID:18502763 -7.4.2.8 * yersinia sp. (in: enterobacteria) 64000.0 1 PMID:18452514 -7.5.2.1 * alicyclobacillus acidocaldarius 42977.0 1 PMID:15136159 -7.5.2.1 * escherichia coli 170000.0 1 PMID:2026607 -7.5.2.1 * thermococcus litoralis 42000.0 1 PMID:11453995 -7.5.2.13 * sulfolobus acidocaldarius 46000.0 1 PMID:29150511 -7.5.2.2 * escherichia coli 35700.0 5 PMID:15636583 -7.5.2.3 * aspergillus fumigatus 160000.0 1 PMID:11244067 -7.5.2.3 * sinorhizobium meliloti 67100.0 6 PMID:8302219;PMID:8544814;PMID:9023225 -7.5.2.6 * escherichia coli 65000.0 2 PMID:22593573;PMID:23306205 -7.5.2.6 * salmonella enterica subsp. enterica serovar typhimurium 134000.0 1 PMID:23723071 -7.6.2.1 * bos taurus 132000.0 1 PMID:19778899 -7.6.2.1 * escherichia coli 65000.0 1 PMID:20412049 -7.6.2.1 * homo sapiens 170000.0 7 PMID:10856717;PMID:16600198;PMID:17481571;PMID:17523162;PMID:18651749;PMID:19778899;PMID:2544808;PMID:7971987 -7.6.2.1 * mus musculus 160000.0 4 PMID:16618126;PMID:17481571;PMID:19017724 -7.6.2.11 * escherichia coli 45000.0 8 PMID:11421274 -7.6.2.12 * escherichia coli 29800.0 2 PMID:8842709;PMID:9513268 -7.6.2.12 * haemophilus influenzae 30200.0 2 PMID:8302219 -7.6.2.12 * klebsiella pneumoniae 30800.0 3 PMID:7533882 -7.6.2.12 * neisseria meningitidis 30100.0 2 PMID:1659649;PMID:8302219 -7.6.2.12 * pseudomonas aeruginosa 47200.0 2 PMID:9244257 -7.6.2.2 * aspergillus nidulans 158900.0 1 PMID:9180695 -7.6.2.2 * candida albicans 16990.0 1 PMID:26407965 -7.6.2.2 * helicoverpa armigera 150000.0 2 PMID:17215890;PMID:20188065 -7.6.2.2 * homo sapiens 290000.0 13 PMID:12676459;PMID:14759224;PMID:15152943;PMID:18313307;PMID:20691149;PMID:22533905;PMID:24825346;PMID:28554189;PMID:34693929;PMID:8725386;PMID:9872059 -7.6.2.2 * lactococcus lactis 74000.0 3 PMID:15192086;PMID:8855237 -7.6.2.2 * streptococcus pneumoniae 130568.0 2 PMID:35066976 -7.6.2.3 * homo sapiens 190000.0 1 PMID:12424247 -7.6.2.4 * arabidopsis thaliana 149400.0 1 PMID:11828016 -7.6.2.4 * homo sapiens 75000.0 2 PMID:16344115;PMID:17542813 -7.6.2.4 * mus musculus 515000.0 7 PMID:15276650;PMID:28258215 -7.6.2.4 * rattus norvegicus 87000.0 5 PMID:16412981;PMID:16946495;PMID:8900413 -7.6.2.7 * bacillus subtilis 36400.0 3 PMID:9782504 -7.6.2.7 * escherichia coli 32000.0 3 PMID:8808933 -7.6.2.8 * bacteroides thetaiotaomicron 64000.0 1 PMID:35227073 -7.6.2.8 * escherichia coli 66000.0 8 PMID:21345797;PMID:3528128;PMID:3528129 -7.6.2.8 * homo sapiens 360000.0 1 PMID:33845046 -7.6.2.8 * salmonella enterica subsp. enterica serovar typhimurium 60000.0 1 PMID:2656634 -7.6.2.9 * aphanothece halophytica 64660.0 1 PMID:16957224 -7.6.2.9 * bacillus subtilis 95400.0 5 PMID:14623183;PMID:16445940;PMID:8752321 -7.6.2.9 * lactococcus lactis 61966.0 2 PMID:10515910 diff --git a/databases/sa.tsv b/databases/sa.tsv deleted file mode 100644 index 407e8c7d..00000000 --- a/databases/sa.tsv +++ /dev/null @@ -1,17831 +0,0 @@ -# BRENDA release 2026.1 generated 2026-05-28 - CC BY 4.0 - specific activity in umol/min/mg -ec_code substrate organism sa_max sa_median n references -1.1.1.1 * [candida] maris 27.6 27.6 1 PMID:21670533 -1.1.1.1 * [candida] sp. 49.3 49.3 1 * -1.1.1.1 * acetivibrio thermocellus 7.68 3.8649999999999998 2 PMID:25666131 -1.1.1.1 * acetobacter aceti 66.0 66.0 1 * -1.1.1.1 * acetobacter pasteurianus 597.0 479.0 2 PMID:12834271 -1.1.1.1 * acetobacter senegalensis 6.3 6.3 1 * -1.1.1.1 * aminobacter aminovorans 4.3 4.3 1 * -1.1.1.1 * arabidopsis thaliana 42.7 42.7 1 PMID:30252897 -1.1.1.1 * carboxydothermus hydrogenoformans 4.75 4.75 1 PMID:23160740 -1.1.1.1 * citrobacter sp. s-77 1.7 1.7 1 PMID:26216639 -1.1.1.1 * devosia riboflavina 3.12 3.12 1 * -1.1.1.1 * drosophila melanogaster 55.0 55.0 1 * -1.1.1.1 * entamoeba histolytica 0.092 0.092 1 PMID:12058720 -1.1.1.1 * equus caballus 4.2 3.2 3 PMID:20851;PMID:6755178 -1.1.1.1 * flavobacterium frigidimaris 43.0 43.0 1 PMID:17072683 -1.1.1.1 * fragaria x ananassa 2.5 2.5 1 PMID:16390205 -1.1.1.1 * geobacillus thermodenitrificans 447.6 447.6 1 PMID:19383697 -1.1.1.1 * gluconacetobacter diazotrophicus 5.7 5.7 1 * -1.1.1.1 * homo sapiens 3.3 1.3 5 PMID:236461;PMID:6375718;PMID:6397223;PMID:7011320;PMID:836289 -1.1.1.1 * kangiella koreensis 79.6 79.6 1 PMID:25481533 -1.1.1.1 * komagataeibacter medellinensis 9.9 9.9 1 * -1.1.1.1 * komagataeibacter xylinus 11.4 11.4 1 * -1.1.1.1 * leifsonia sp. 10.3 10.3 1 PMID:16000771 -1.1.1.1 * magnusiomyces capitatus 31.0 31.0 1 PMID:17368401 -1.1.1.1 * megalodesulfovibrio gigas 31.8 31.8 1 PMID:8491707 -1.1.1.1 * mesocricetus auratus 4.0 2.5 3 PMID:3178842;PMID:8730210 -1.1.1.1 * methylorubrum extorquens 2.3 2.3 1 PMID:16390205 -1.1.1.1 * meyerozyma guilliermondii 79.1 79.1 1 * -1.1.1.1 * mus musculus 64.0 8.08 3 PMID:6360682 -1.1.1.1 * oenococcus oeni 1.1 0.25 4 PMID:23385476 -1.1.1.1 * oryctolagus cuniculus 2.69 2.69 1 PMID:3161873 -1.1.1.1 * petroselinum crispum 17.17 17.17 1 * -1.1.1.1 * picrophilus oshimae 0.225 0.225 1 PMID:17989975 -1.1.1.1 * pyrococcus furiosus 108.0 55.0 2 PMID:16391048 -1.1.1.1 * rattus norvegicus 32.5 0.62 7 PMID:3816781 -1.1.1.1 * saara hardwickii 0.62 0.62 1 PMID:8612630 -1.1.1.1 * saccharolobus solfataricus 10.1 3.92 13 PMID:10074357;PMID:11265460;PMID:1463738;PMID:17824633;PMID:19588068;PMID:3115775;PMID:7770449;PMID:8550434 -1.1.1.1 * saccharomyces cerevisiae 190.86 1.74 9 PMID:28265724;PMID:32967812 -1.1.1.1 * sporotrichum pulverulentum 196.3 196.3 1 * -1.1.1.1 * sulfolobus acidocaldarius 6.6 6.6 1 PMID:20049620 -1.1.1.1 * sulfolobus sp. 2.88 1.55 2 PMID:8550434 -1.1.1.1 * sulfurisphaera tokodaii 1.14 1.14 1 PMID:19139244 -1.1.1.1 * sus scrofa 0.63 0.41500000000000004 2 PMID:13747804 -1.1.1.1 * thermoanaerobacter ethanolicus 2.6 2.6 1 PMID:17981479 -1.1.1.1 * thermoanaerobacterium saccharolyticum 1.52 1.1 2 PMID:25666131 -1.1.1.1 * thermomicrobium roseum 1.28 1.28 1 PMID:12031468 -1.1.1.1 * thermoplasma acidophilum 628.7 323.15000000000003 2 PMID:19058034 -1.1.1.1 * thermus sp. 20.6 17.8 2 PMID:18704396 -1.1.1.1 * thermus thermophilus 151.1 151.1 1 PMID:18456852 -1.1.1.1 * triticum monococcum 55900.0 55900.0 1 PMID:485168 -1.1.1.1 * zea mays 70.0 70.0 1 PMID:8166623 -1.1.1.1 * zymomonas mobilis 470.0 281.5 2 * -1.1.1.10 * aspergillus niger 200.0 1.8 5 PMID:20654618 -1.1.1.10 * cavia porcellus 143.0 143.0 1 PMID:11882650 -1.1.1.10 * chlorella sorokiniana 0.026 0.026 1 PMID:25342968 -1.1.1.10 * mesocricetus auratus 642.0 642.0 1 PMID:11882650 -1.1.1.10 * pantoea ananatis 0.23 0.23 1 PMID:2981816 -1.1.1.10 * rhizomucor pusillus 77.3 57.8 3 PMID:28471330 -1.1.1.100 * brassica juncea 0.0366 0.0366 1 PMID:6833216 -1.1.1.100 * brassica napus 136000.0 136000.0 1 PMID:1562581 -1.1.1.100 * carthamus tinctorius 0.0197 0.019299999999999998 2 PMID:6833216;PMID:7125663 -1.1.1.100 * cuphea lanceolata 180400.0 83140.0 3 PMID:1376402 -1.1.1.100 * cuphea lutea 0.0168 0.0168 1 PMID:6833216 -1.1.1.100 * escherichia coli 4930.0 2465.0016 2 PMID:4381013;PMID:6756317 -1.1.1.100 * homo sapiens 20.8 12.0 4 PMID:25203508 -1.1.1.100 * lathyrus oleraceus 0.0132 0.0132 1 PMID:6833216 -1.1.1.100 * persea americana 9401.0 490.0 4 PMID:2244875 -1.1.1.100 * plasmodium falciparum 70.6 59.8 5 PMID:15939298;PMID:16934037;PMID:18721141 -1.1.1.100 * spinacia oleracea 7.95 0.0192 3 PMID:6756317;PMID:6833216 -1.1.1.100 * synechococcus elongatus pcc 7942 = fachb-805 38.29 0.16 11 PMID:18791006 -1.1.1.100 * xanthomonas campestris pv. campestris 0.0197 0.00421 7 PMID:29739899 -1.1.1.101 * cavia porcellus 62.5 62.5 1 PMID:1495422;PMID:2335525 -1.1.1.101 * mus musculus 0.0296 0.0186 3 PMID:10734090;PMID:3954368 -1.1.1.101 * rattus norvegicus 0.00546 0.0035199999999999997 2 PMID:500614;PMID:6271231 -1.1.1.101 * saccharomyces cerevisiae 0.00393 0.00393 1 PMID:7897322 -1.1.1.102 * bos taurus 25.0 25.0 1 PMID:4387676 -1.1.1.102 * mus musculus 0.000121 0.000121 1 PMID:1317856 -1.1.1.103 * acetoanaerobium sticklandii 234.0 234.0 1 PMID:7763136 -1.1.1.103 * aquarana catesbeiana 339.0 339.0 1 PMID:14165492 -1.1.1.103 * arthrobacter sp. 6.05 6.05 1 * -1.1.1.103 * bos taurus 0.055 0.055 1 * -1.1.1.103 * capra hircus 8.45 8.45 1 PMID:3888978 -1.1.1.103 * cupriavidus necator 65.0 53.6 2 PMID:21073854 -1.1.1.103 * cytophaga sp. 722.0 284.0 5 PMID:12867457 -1.1.1.103 * escherichia coli k-12 685.0 34.0 5 PMID:3056527;PMID:33672;PMID:3518793;PMID:6780553 -1.1.1.103 * gallus gallus 18920.0 9469.5 2 PMID:11470445;PMID:7028754 -1.1.1.103 * pyrococcus horikoshii 3.43 3.43 1 PMID:15902509 -1.1.1.103 * rattus norvegicus 0.062 0.032 3 * -1.1.1.103 * staphylococcus aureus 3.28 3.28 1 PMID:4284408 -1.1.1.103 * sus scrofa 380.0 380.0 1 PMID:7827500 -1.1.1.104 * oryctolagus cuniculus 5.21 5.21 1 PMID:13914427 -1.1.1.105 * branchiostoma floridae 0.0014 0.000825 2 PMID:17608724 -1.1.1.105 * kangiella koreensis 0.024 0.0213 3 PMID:25481533 -1.1.1.106 * pseudomonas fluorescens 19.34 19.34 1 PMID:99175 -1.1.1.106 * pseudomonas sp. p2 6.0 6.0 1 PMID:4287370 -1.1.1.107 * escherichia coli 47.6 30.65 2 PMID:19111641 -1.1.1.107 * mesorhizobium loti 103.9 95.95 2 PMID:16824480;PMID:20516609 -1.1.1.107 * microbacterium luteolum 635.0 635.0 1 PMID:15226311 -1.1.1.108 * agrobacterium sp. 16.75 0.35 3 PMID:8645721 -1.1.1.108 * pseudomonas aeruginosa 600.0 199.5 4 PMID:2253348;PMID:4302217;PMID:4310279 -1.1.1.108 * pseudomonas putida 240.0 55.3 3 PMID:16345505;PMID:3058208 -1.1.1.108 * rhizobium sp. 23.3 23.3 1 PMID:20530902 -1.1.1.108 * rhizobium sp. ys-240 23.3 23.3 1 * -1.1.1.108 * xanthomonas translucens 21.0 21.0 1 * -1.1.1.11 * candida albicans 0.37 0.27 2 PMID:8407803 -1.1.1.11 * candida tropicalis 187.0 141.5 2 PMID:7698655;PMID:8250887 -1.1.1.11 * gluconobacter oxydans 68.5 2.8 13 PMID:19629658 -1.1.1.11 * gluconobacter sp. jx-05 87.7 9.0 9 PMID:28364633 -1.1.1.11 * klebsiella aerogenes 56.0 37.1 3 PMID:13762204;PMID:13786517;PMID:393250 -1.1.1.11 * scheffersomyces stipitis 68.25 0.78 3 PMID:7483848 -1.1.1.110 * candida maltosa 1170.0 587.25 2 * -1.1.1.111 * delftia acidovorans 12.0 9.5 2 PMID:4303364 -1.1.1.112 * bos taurus 0.74 0.74 1 PMID:4397102 -1.1.1.112 * homo sapiens 0.118 0.01025 6 PMID:3898609 -1.1.1.112 * macaca fuscata 11.1 11.1 1 PMID:2674111 -1.1.1.112 * oryctolagus cuniculus 7.77 4.03 7 PMID:3527067 -1.1.1.114 * micrococcus sp. 0.102 0.102 1 * -1.1.1.116 * candida albicans 2.2 2.2 1 PMID:8841374 -1.1.1.116 * neurospora crassa 1.11 1.11 1 PMID:6450742 -1.1.1.116 * saccharomyces cerevisiae 1.8 0.900355 2 PMID:17097644 -1.1.1.116 * sus scrofa 0.605 0.5185 2 PMID:4355268 -1.1.1.117 * pseudomonas sp. 1350.0 1350.0 1 PMID:5845847 -1.1.1.118 * pseudomonas sp. 66.0 66.0 1 PMID:236432 -1.1.1.118 * saccharolobus solfataricus 437.0 218.85 2 PMID:3827812 -1.1.1.118 * synthetic construct 86.3 47.4 2 * -1.1.1.119 * gluconobacter cerinus 10.1 10.1 1 PMID:236431;PMID:4384672 -1.1.1.119 * gluconobacter oxydans 140.0 140.0 1 * -1.1.1.119 * haloferax mediterranei 550.0 550.0 1 PMID:8925901 -1.1.1.12 * [candida] arabinofermentans 0.93 0.93 1 PMID:17627668 -1.1.1.12 * aspergillus niger 11.7 11.7 1 PMID:20414651 -1.1.1.12 * meyerozyma caribbica 4.9 2.0 3 PMID:27506274 -1.1.1.12 * meyerozyma guilliermondii 0.15 0.15 1 PMID:17627668 -1.1.1.12 * penicillium chrysogenum 25.3 25.3 1 PMID:20414651 -1.1.1.12 * trichoderma reesei 105.0 34.0 4 PMID:20414651;PMID:24342239 -1.1.1.120 * pseudomonas putida 4.88 4.88 1 PMID:4387016 -1.1.1.120 * pseudomonas sp. 170.0 170.0 1 PMID:5845847 -1.1.1.121 * pseudomonas sp. 13.8 13.8 1 PMID:4335867 -1.1.1.121 * thermoplasma acidophilum 31.0 19.5 4 PMID:15618614 -1.1.1.122 * acinetobacter sp. 217.0 109.65 2 PMID:24320238 -1.1.1.122 * agrobacterium tumefaciens 375.0 53.0 3 PMID:1525177 -1.1.1.122 * oryctolagus cuniculus 1.03 1.03 1 PMID:521443 -1.1.1.122 * sus scrofa 433.0 433.0 1 PMID:4309152 -1.1.1.122 * trinickia caryophylli 3.66 3.66 1 PMID:40609 -1.1.1.123 * bemisia argentifolii 1.25 1.01 2 PMID:12770392 -1.1.1.123 * clostridium pasteurianum 48.9 48.9 1 PMID:33616697 -1.1.1.123 * corynebacterium sp. 67.3 67.3 1 * -1.1.1.123 * saccharomyces cerevisiae 28.4 28.4 1 PMID:236429;PMID:4392628 -1.1.1.124 * erwinia sp. 2450.0 2450.0 1 PMID:3178725 -1.1.1.124 * gluconobacter cerinus 627.0 627.0 1 PMID:4379259 -1.1.1.124 * gluconobacter oxydans 620.0 311.5 2 * -1.1.1.125 * pseudomonas sp. 32.0 32.0 1 PMID:14285233 -1.1.1.126 * pseudomonas sp. 15.9 15.9 1 PMID:14488585 -1.1.1.127 * dickeya chrysanthemi 39.0 39.0 1 * -1.1.1.127 * pseudomonas sp. 19.5 19.5 1 PMID:13986017 -1.1.1.129 * pseudomonas sp. 124.0 124.0 1 PMID:14154441 -1.1.1.130 * klebsiella aerogenes 8.06 8.06 1 PMID:13926592 -1.1.1.132 * arthrobacter sp. 0.39 0.3175 2 PMID:14245351 -1.1.1.132 * azotobacter vinelandii 0.0025 0.0022500000000000003 2 * -1.1.1.132 * pseudomonas aeruginosa 1068.0 0.0179 68 PMID:10209766;PMID:1367514;PMID:2470755;PMID:7521247;PMID:8878949 -1.1.1.133 * acanthamoeba polyphaga mimivirus 0.0011 0.0011 1 PMID:20538863 -1.1.1.133 * salmonella enterica 44.0 44.0 1 PMID:10455186 -1.1.1.136 * micrococcus luteus 41.0 41.0 1 PMID:4044544 -1.1.1.137 * lacticaseibacillus casei 76.8 76.8 1 PMID:23564164 -1.1.1.137 * lactiplantibacillus plantarum 49.3 49.3 1 * -1.1.1.138 * agaricus bisporus 194.4 171.5 2 * -1.1.1.138 * aspergillus parasiticus 130.0 130.0 1 PMID:7085559 -1.1.1.138 * cladosporium herbarum 277.0 277.0 1 PMID:16608840 -1.1.1.138 * fusarium graminearum 0.54 0.54 1 PMID:12453571 -1.1.1.138 * gluconobacter oxydans 235.0 235.0 1 * -1.1.1.138 * lactobacillus intermedius 331.0 331.0 1 PMID:15059000 -1.1.1.138 * limosilactobacillus reuteri 124.6 62.605 2 PMID:15630578 -1.1.1.138 * penicillium chrysogenum 18.1 18.1 1 * -1.1.1.138 * starmerella magnoliae 315.0 5.15 8 PMID:12902227;PMID:17120092 -1.1.1.138 * tuber borchii 350.0 350.0 1 PMID:17317242 -1.1.1.138 * uromyces viciae-fabae 1.0 0.7 2 PMID:15618426 -1.1.1.14 * [candida] boidinii 30.94 30.94 1 * -1.1.1.14 * bacillus subtilis 13.6 13.6 1 PMID:1460002 -1.1.1.14 * bos taurus 52.0 52.0 1 PMID:9143345 -1.1.1.14 * cereibacter sphaeroides 42.3 42.3 1 PMID:7551049 -1.1.1.14 * deinococcus geothermalis 4659.0 1427.0 5 PMID:22883556 -1.1.1.14 * gluconobacter oxydans 136.5 90.9 2 PMID:11866120 -1.1.1.14 * homo sapiens 7.62 7.62 1 PMID:12595725 -1.1.1.14 * malus domestica 1.105 1.105 1 * -1.1.1.14 * ovis aries 14.4 14.4 1 PMID:13914358 -1.1.1.14 * priestia megaterium 2.7 2.7 1 * -1.1.1.14 * pseudomonas sp. 89.5 89.5 1 * -1.1.1.14 * pyrus pyrifolia 55.0 55.0 1 PMID:10963448 -1.1.1.14 * rattus norvegicus 7.47 7.47 1 PMID:667078;PMID:7144570 -1.1.1.14 * scheffersomyces stipitis 58.1 58.1 1 * -1.1.1.140 * clostridium pasteurianum 43.2 43.2 1 PMID:4318899 -1.1.1.140 * escherichia coli 180.0 180.0 1 PMID:6384188 -1.1.1.140 * lacticaseibacillus casei 0.222 0.202 2 PMID:16002237 -1.1.1.141 * bos taurus 70.0 35.0007 2 PMID:4337429;PMID:4453620 -1.1.1.141 * gallus gallus 0.025 0.025 1 PMID:234431 -1.1.1.141 * homo sapiens 24.0 4.2 10 PMID:1117007;PMID:12144871;PMID:1309294;PMID:1508959;PMID:2286636;PMID:2337593;PMID:241691;PMID:7132749;PMID:8086429;PMID:8508808 -1.1.1.141 * oryctolagus cuniculus 25.0 12.5000385 2 PMID:2255767;PMID:3954355 -1.1.1.141 * platyrrhini 0.136 0.136 1 PMID:234431 -1.1.1.141 * sus scrofa 13.2 6.6049 2 PMID:2393668;PMID:803247 -1.1.1.144 * pseudomonas sp. 13.0 13.0 1 PMID:4234666 -1.1.1.145 * bos taurus 45.0 0.34640000000000004 4 PMID:3867664;PMID:4226148;PMID:8119176 -1.1.1.145 * digitalis lanata 0.0016 0.0016 1 PMID:10550629 -1.1.1.145 * homo sapiens 0.155 0.0172 9 PMID:10514560;PMID:10686147;PMID:11463578;PMID:7918109 -1.1.1.145 * ovis aries 0.19 0.19 1 PMID:4274151 -1.1.1.145 * pseudomonas sp. 88.9 88.9 1 PMID:495965 -1.1.1.145 * sus scrofa 2.88 0.5065 6 PMID:7841933;PMID:8702847 -1.1.1.146 * bos taurus 0.00017 0.00017 1 PMID:4384445 -1.1.1.146 * cavia porcellus 0.00045 0.00033 2 PMID:4384445 -1.1.1.146 * homo sapiens 91.36 3.84 3 PMID:11841241;PMID:15330095 -1.1.1.146 * oryctolagus cuniculus 0.00018 0.000145 2 PMID:4384445 -1.1.1.146 * rattus sp. 0.00014 0.00014 1 PMID:4384445 -1.1.1.148 * eubacterium sp. 3.25 2.525 2 PMID:8071614 -1.1.1.148 * gallus gallus 0.2 0.2 1 PMID:6593066 -1.1.1.148 * oryctolagus cuniculus 0.18 0.041 5 PMID:849262 -1.1.1.149 * [clostridium] scindens 0.282 0.282 1 PMID:2722736 -1.1.1.149 * bos taurus 0.115 0.115 1 PMID:3867809 -1.1.1.149 * homo sapiens 1.3 0.669 2 PMID:19237229;PMID:6935192 -1.1.1.149 * rattus norvegicus 8.318 0.616 20 PMID:10417353;PMID:1888758;PMID:513762;PMID:6586205;PMID:8977402 -1.1.1.149 * sus scrofa 0.081 0.081 1 PMID:4400473 -1.1.1.149 * tetrahymena pyriformis 6.2 3.106 2 PMID:7484385;PMID:8280099 -1.1.1.149 * tetrahymena thermophila 5.0 2.512 2 PMID:7484385 -1.1.1.153 * bos taurus 9.76 9.76 1 PMID:8493908 -1.1.1.153 * chlorobaculum tepidum 31.5 31.5 1 * -1.1.1.153 * drosophila melanogaster 0.022 0.022 1 PMID:8936046 -1.1.1.153 * homo sapiens 1.8 1.365 2 PMID:23640889;PMID:8304110 -1.1.1.153 * rattus norvegicus 18.0 9.85 2 PMID:2201030;PMID:7052139 -1.1.1.154 * arthrobacter allantoicus 10.6 10.6 1 PMID:4399430 -1.1.1.156 * gluconobacter oxydans 13.71 6.885000000000001 2 PMID:18685208 -1.1.1.156 * phycomyces blakesleeanus 31.1 31.1 1 * -1.1.1.156 * schizosaccharomyces pombe 15.7 0.7 4 PMID:2621446 -1.1.1.157 * clostridium kluyveri 445.0 368.5 2 PMID:4092496;PMID:4405720;PMID:6149704 -1.1.1.157 * desulfococcus biacutus 23.3 18.7 2 PMID:29528562 -1.1.1.159 * acinetobacter calcoaceticus 70.0 70.0 1 PMID:25131646 -1.1.1.159 * acinetobacter lwoffii 0.11 0.07250000000000001 2 PMID:18674553 -1.1.1.159 * bacteroides fragilis 351.0 175.66 2 PMID:14756531 -1.1.1.159 * brevibacterium fuscum 2900.0 1650.0 4 * -1.1.1.159 * clostridium sardiniense 70.0 37.85 2 PMID:25131646;PMID:30734123 -1.1.1.159 * escherichia coli 4164.0 3486.0 9 PMID:2186848;PMID:2698265 -1.1.1.159 * eubacterium sp. 374.0 353.0 2 PMID:1856160 -1.1.1.159 * paraclostridium sordellii 1.1 1.1 1 PMID:8050999 -1.1.1.159 * pseudomonas sp. 900.0 900.0 1 PMID:25131646 -1.1.1.159 * stenotrophomonas maltophilia 70.0 70.0 2 PMID:16307764;PMID:25131646 -1.1.1.159 * unidentified microorganism 217.6 188.3 3 PMID:33592267 -1.1.1.162 * bos taurus 123.0 97.15 2 PMID:4152124;PMID:6292658 -1.1.1.162 * gallus gallus 320.0 120.0 13 PMID:7358641;PMID:9538249 -1.1.1.163 * pseudomonas sp. 0.68 0.68 1 PMID:4349113 -1.1.1.164 * acinetobacter sp. 0.0059 0.00285 4 PMID:2933391 -1.1.1.165 * fusarium merismoides 751.1 751.1 1 * -1.1.1.166 * lactiplantibacillus plantarum 58.9 58.9 1 PMID:4375976 -1.1.1.168 * candida dubliniensis 49.1 49.1 1 PMID:31000167 -1.1.1.168 * candida parapsilosis 251.0 212.0 2 PMID:2644973 -1.1.1.168 * saccharomyces cerevisiae 69.2 69.2 1 PMID:374974 -1.1.1.169 * corynebacterium glutamicum 0.0126 0.0126 1 PMID:12948643 -1.1.1.169 * escherichia coli 19.0 19.0 1 PMID:10736170 -1.1.1.169 * saccharomyces cerevisiae 0.38 0.38 1 * -1.1.1.169 * salmonella enterica subsp. enterica serovar typhimurium 64.3 61.0 3 PMID:9488683 -1.1.1.169 * stenotrophomonas maltophilia 669.0 651.0 2 PMID:3042788 -1.1.1.17 * acinetobacter baumannii 20.0 20.0 1 PMID:29575790 -1.1.1.17 * acinetobacter baylyi 130.0 130.0 1 PMID:23414076 -1.1.1.17 * amycolatopsis lactamdurans 0.03 0.03 1 PMID:194534 -1.1.1.17 * aspergillus fumigatus 169.0 93.3 2 PMID:18452897 -1.1.1.17 * aspergillus nidulans 0.28 0.20500000000000002 2 PMID:163669 -1.1.1.17 * aspergillus niger 453.9 68.3 5 PMID:20305000;PMID:4019499;PMID:7030216 -1.1.1.17 * aspergillus parasiticus 190.0 190.0 1 PMID:4019499 -1.1.1.17 * bacillus methanolicus 0.05 0.035 2 PMID:31417519 -1.1.1.17 * beauveria bassiana 673.7 673.7 1 PMID:19896118 -1.1.1.17 * brochothrix thermosphacta 18.0 9.045 2 * -1.1.1.17 * caloglossa continua 228.6 228.6 1 PMID:12972650 -1.1.1.17 * cryptococcus neoformans 116.0 58.05 2 PMID:11021946 -1.1.1.17 * ectocarpus siliculosus 0.046 0.016 15 PMID:20981555;PMID:26232554 -1.1.1.17 * eimeria tenella 0.01 0.01 1 PMID:2538747 -1.1.1.17 * escherichia coli 715.0 608.5 2 PMID:3545182;PMID:6384188 -1.1.1.17 * micromonospora sp. 0.03 0.03 1 PMID:194534 -1.1.1.17 * streptococcus mutans 0.43 0.43 1 PMID:873604 -1.1.1.17 * vibrio cholerae serotype o1 3.32 3.32 1 PMID:21952367 -1.1.1.170 * rattus sp. 0.11 0.11 1 PMID:4401584 -1.1.1.173 * aureobasidium pullulans 2.0 2.0 1 * -1.1.1.173 * debaryomyces hansenii 53.3 53.3 1 PMID:18505728 -1.1.1.173 * scheffersomyces stipitis 50.4 15.25 4 PMID:18400031;PMID:18505728 -1.1.1.173 * sulfobacillus thermosulfidooxidans 33.0 11.61 4 PMID:25617114 -1.1.1.174 * acinetobacter sp. 26.5 13.675 2 PMID:856571 -1.1.1.175 * arthrobacter sp. 24.12 24.12 1 * -1.1.1.175 * pseudomonas sp. 143.0 60.3 3 PMID:6755170 -1.1.1.176 * acinetobacter lwoffii 0.3 0.1635 2 PMID:18674553 -1.1.1.177 * archaeoglobus fulgidus 44.0 24.0 2 PMID:15557260 -1.1.1.178 * pseudomonas putida 21.7 18.95 2 PMID:4150713 -1.1.1.179 * haloarcula marismortui 100.0 100.0 1 PMID:15342590 -1.1.1.179 * haloferax volcanii 24.1 10.0 3 PMID:19584053 -1.1.1.179 * macaca fuscata 33.0 21.0 2 PMID:11097839;PMID:11306093 -1.1.1.179 * sus scrofa 7.6 7.35 2 PMID:11306093;PMID:2327952 -1.1.1.18 * bacillus subtilis 34.3 23.15 2 PMID:112095;PMID:1761221 -1.1.1.18 * galdieria sulphuraria 50.0 50.0 1 * -1.1.1.18 * klebsiella aerogenes 280.0 280.0 1 PMID:5905122 -1.1.1.18 * myxozyma melibiosi 1.68 1.68 1 PMID:4351258 -1.1.1.18 * sinorhizobium fredii 0.07 0.07 1 PMID:11274120 -1.1.1.18 * sinorhizobium meliloti 0.241 0.241 1 PMID:9802033 -1.1.1.181 * oryctolagus cuniculus 0.23 0.23 1 PMID:6937465 -1.1.1.183 * carpoglyphus lactis 31.0 31.0 1 PMID:18422649 -1.1.1.183 * citrus sp. 0.203 0.203 1 * -1.1.1.183 * persicaria minor 0.261 0.175 3 PMID:22878188 -1.1.1.184 * [candida] boidinii 4.65 2.5650000000000004 2 PMID:31065494 -1.1.1.184 * candida parapsilosis 42.7 6.645 32 * -1.1.1.184 * cylindrocarpon sclerotigenum 125.3 125.3 1 PMID:12843676 -1.1.1.184 * geotrichum candidum 306.0 306.0 1 PMID:18513958 -1.1.1.184 * gluconobacter oxydans 92.8 42.55 18 PMID:20414648;PMID:23587814 -1.1.1.184 * homo sapiens 1533.0 161.6 3 PMID:18579125;PMID:7005231 -1.1.1.184 * kluyveromyces lactis 50.8 50.8 1 PMID:12353647 -1.1.1.184 * kluyveromyces marxianus 6.9 2.1 18 PMID:26223585 -1.1.1.184 * komagataella pastoris 1502.0 6.3 7 * -1.1.1.184 * neurospora crassa 468.0 89.0 5 PMID:22113019 -1.1.1.184 * pichia kudriavzevii 12.6 12.6 1 * -1.1.1.184 * rhodotorula glutinis 3.0 3.0 1 PMID:15665471 -1.1.1.184 * scheffersomyces stipitis 337.0 337.0 1 PMID:19574038 -1.1.1.184 * sporobolomyces salmonicolor 1.4 0.028 13 PMID:16826293;PMID:18205368 -1.1.1.184 * starmerella magnoliae 27.8 13.9075 2 PMID:15784983;PMID:16709061 -1.1.1.184 * sus scrofa 0.5 0.5 1 PMID:12604222 -1.1.1.184 * thermotoga maritima 7.9 7.9 2 PMID:23338701 -1.1.1.185 * gallus gallus 0.4 0.4 1 PMID:6755184 -1.1.1.187 * pseudomonas sp. 1.98 1.98 1 PMID:4398966 -1.1.1.188 * bos taurus 0.41 0.115 25 PMID:1339268;PMID:1605628;PMID:1958196;PMID:23747692;PMID:3858278 -1.1.1.188 * homo sapiens 2.4 0.2 3 PMID:21306562;PMID:23747692 -1.1.1.188 * mus musculus 3.6 2.145 2 PMID:18006499;PMID:21306562 -1.1.1.188 * oryctolagus cuniculus 0.0015 0.0015 1 PMID:7132748;PMID:7248317 -1.1.1.188 * sus scrofa 0.062 0.062 1 PMID:18006499 -1.1.1.188 * trypanosoma brucei 0.86 0.86 1 PMID:11067881 -1.1.1.189 * gallus gallus 5.73 5.73 1 PMID:166995 -1.1.1.189 * homo sapiens 0.034 0.00045 4 PMID:1597188;PMID:236730;PMID:3459656;PMID:6586494 -1.1.1.189 * oryctolagus cuniculus 3.25 3.25 1 PMID:8529651 -1.1.1.189 * sus scrofa 0.02 0.02 1 PMID:1597188 -1.1.1.19 * bos taurus 0.0025 0.0025 2 PMID:8898089 -1.1.1.19 * homo sapiens 1.339 1.339 1 PMID:8343612 -1.1.1.19 * rattus norvegicus 0.0025 0.0025 2 PMID:8898089 -1.1.1.19 * sus scrofa 5.45 5.45 1 PMID:6755181 -1.1.1.191 * cucumis sativus 0.24 0.027 4 * -1.1.1.191 * phycomyces blakesleeanus 0.11 0.08499999999999999 2 * -1.1.1.194 * glycine max 0.36 0.36 1 PMID:1250 -1.1.1.194 * saccharum officinarum 36.21 18.25 2 * -1.1.1.194 * streptomyces sp. 10.7 5.484999999999999 2 PMID:23500723 -1.1.1.195 * aralia cordata 7e-05 7e-05 1 PMID:7763430 -1.1.1.195 * eucalyptus gunnii 4.7 2.515 2 PMID:7547988 -1.1.1.195 * forsythia suspensa 3.5 3.5 1 * -1.1.1.195 * glycine max 56.4 30.13 2 PMID:1250;PMID:572771 -1.1.1.195 * leucaena leucocephala 48.74 43.269999999999996 2 PMID:24064207;PMID:24532464 -1.1.1.195 * oryza sativa 0.0036 0.0025 2 PMID:16443696 -1.1.1.195 * phaseolus vulgaris 0.0034 0.0034 1 PMID:7765663 -1.1.1.195 * picea abies 64.56 64.56 1 PMID:7042334 -1.1.1.195 * pinus radiata 0.00125 0.00125 1 PMID:16356917 -1.1.1.195 * pinus taeda 0.18 0.18 1 PMID:16668801 -1.1.1.195 * pinus thunbergii 0.6 0.6 1 * -1.1.1.195 * populus x canadensis 1.71 1.71 1 PMID:6365550 -1.1.1.195 * triticum aestivum 0.006 0.006 1 * -1.1.1.196 * sus scrofa 0.0212 0.0114975 2 PMID:6958674;PMID:7132752;PMID:7354056 -1.1.1.197 * homo sapiens 0.09 0.09 1 PMID:3624267 -1.1.1.197 * macaca fascicularis 0.0243 0.0061 5 PMID:11872167 -1.1.1.197 * sus scrofa 7.5 7.15 2 PMID:7236298 -1.1.1.198 * artemisia annua 147.4 11.915 6 PMID:20621795 -1.1.1.198 * pseudomonas sp. tcu-hl1 0.122 0.028 13 PMID:34262629 -1.1.1.198 * salvia officinalis 30.0 13.0 7 PMID:34262629 -1.1.1.198 * salvia rosmarinus 0.03 0.0048 13 PMID:34262629 -1.1.1.2 * acinetobacter sp. 560.0 280.85 2 PMID:11097895 -1.1.1.2 * bos taurus 8.94 0.46430000000000005 4 PMID:4146452;PMID:4393513;PMID:6753832 -1.1.1.2 * canis lupus familiaris 1.35 1.35 1 PMID:1907200 -1.1.1.2 * drosophila melanogaster 2.47 2.47 1 PMID:744352 -1.1.1.2 * euglena gracilis 116.2 38.68 8 * -1.1.1.2 * gallus sp. 20.0 19.7 5 PMID:6343086;PMID:744352 -1.1.1.2 * geobacillus thermodenitrificans 363.6 363.6 1 PMID:19383697 -1.1.1.2 * homo sapiens 29.62 15.0 4 PMID:16919;PMID:6753936 -1.1.1.2 * levilactobacillus brevis 8.1 3.9 4 PMID:15549291 -1.1.1.2 * marinobacter nauticus vt8 0.085 0.085 1 PMID:19270127 -1.1.1.2 * moorella sp. huc22-1 50.4 2.9 5 PMID:17318639 -1.1.1.2 * mycolicibacterium smegmatis 0.024 0.024 1 PMID:11257547 -1.1.1.2 * pseudothermotoga hypogea 57.0 57.0 1 PMID:17294170 -1.1.1.2 * pyrococcus furiosus 72.3 0.73 7 PMID:18452026;PMID:9973342 -1.1.1.2 * rattus norvegicus 211.0 8.215 8 PMID:2500152;PMID:3084464;PMID:6416297;PMID:6798966;PMID:744352 -1.1.1.2 * saccharomyces cerevisiae 183.0 3.85 18 PMID:11742541;PMID:19577617;PMID:744352;PMID:9327572 -1.1.1.2 * scheffersomyces stipitis 15.56 6.745 4 PMID:23912116 -1.1.1.2 * sporobolomyces salmonicolor 81.7 6.48 5 PMID:15703875;PMID:16109633 -1.1.1.2 * sus scrofa 35.0 2.5 11 PMID:235531;PMID:3514645;PMID:4146452;PMID:4402936;PMID:4463942;PMID:6819141;PMID:6989609;PMID:7016111;PMID:744352 -1.1.1.2 * thermoanaerobacter ethanolicus 140.0 104.5 2 PMID:8068002 -1.1.1.2 * thermococcus hydrothermalis 24.0 15.33 2 PMID:10491136 -1.1.1.2 * thermococcus litoralis 31.1 31.1 1 PMID:8135516 -1.1.1.2 * thermococcus sp. 57.0 6.8 5 PMID:19115036;PMID:9209068 -1.1.1.2 * trypanosoma cruzi 2.25 2.25 1 PMID:2663637 -1.1.1.200 * malus domestica 18400.0 7.94 7 PMID:16661614;PMID:16662490;PMID:19799961 -1.1.1.200 * oryza sativa 0.603 0.54 2 PMID:24817585 -1.1.1.201 * [clostridium] scindens 350.0 350.0 1 PMID:25131646 -1.1.1.201 * blautia producta 1.06 1.06 1 PMID:6954878 -1.1.1.201 * collinsella aerofaciens 0.17 0.135 2 PMID:6954878 -1.1.1.201 * oryctolagus cuniculus 0.276 0.276 1 PMID:15276626 -1.1.1.201 * paraclostridium sordellii 350.0 350.0 1 PMID:25131646 -1.1.1.202 * citrobacter freundii 90.9 63.7 4 PMID:22821086;PMID:26966462;PMID:7721705 -1.1.1.202 * clostridium butyricum 25.7 5.505 8 PMID:16391030;PMID:26966462;PMID:30060420 -1.1.1.202 * clostridium pasteurianum 1.7 1.7 1 PMID:9311132 -1.1.1.202 * klebsiella pneumoniae 89.7 11.475 8 PMID:17914171;PMID:26966462 -1.1.1.202 * levilactobacillus brevis 52.7 32.6 3 PMID:26961082;PMID:26966462 -1.1.1.202 * limosilactobacillus reuteri 7.3 7.3 1 PMID:16348177 -1.1.1.202 * oenococcus oeni 1.1 1.1 1 PMID:23385476 -1.1.1.202 * pantoea agglomerans 3.42 3.42 1 PMID:26966462 -1.1.1.203 * agrobacterium tumefaciens 391.0 238.0 2 PMID:28545260 -1.1.1.203 * pseudomonas syringae 81.0 43.1 2 PMID:2471;PMID:4392089 -1.1.1.203 * pseudomonas syringae pv. tomato 10.0 10.0 1 PMID:19060162 -1.1.1.203 * thermobispora bispora 95.17 79.285 2 PMID:29936649 -1.1.1.205 * bacillus cereus 5.03 5.03 1 PMID:9602532 -1.1.1.205 * bacillus subtilis 0.25 0.0124 4 PMID:4972708 -1.1.1.205 * borreliella burgdorferi 0.83 0.83 1 PMID:9268334 -1.1.1.205 * cricetulus griseus 1.08 0.5402750000000001 2 PMID:2902093;PMID:6127996 -1.1.1.205 * escherichia coli 18.75 9.2 3 PMID:1103737;PMID:44191;PMID:6104455 -1.1.1.205 * gallus gallus 1.18 1.18 1 PMID:5787260 -1.1.1.205 * halobacterium salinarum 2.41 1.4700000000000002 2 PMID:15468334 -1.1.1.205 * homo sapiens 1.3 1.3 1 PMID:7763314 -1.1.1.205 * klebsiella aerogenes 17.2 17.2 1 PMID:4290592 -1.1.1.205 * mus musculus 0.236 0.236 1 PMID:2889474 -1.1.1.205 * mycobacterium tuberculosis 2.0 2.0 1 * -1.1.1.205 * rattus norvegicus 1.7 1.19 3 PMID:197916;PMID:2897864;PMID:6140264 -1.1.1.205 * schizosaccharomyces pombe 0.008 0.008 1 PMID:4309177 -1.1.1.205 * sus scrofa 0.57 0.57 1 PMID:8102965 -1.1.1.205 * vigna unguiculata 1.1 1.1 1 PMID:2857550 -1.1.1.206 * atropa acuminata 1.2 1.2 1 PMID:16653065 -1.1.1.206 * atropa belladonna 7.5 7.5 1 PMID:16653065 -1.1.1.206 * datura stramonium 45.0 45.0 1 PMID:16653065 -1.1.1.206 * duboisia hopwoodii 30.0 30.0 1 PMID:16653065 -1.1.1.206 * duboisia leichhardtii 30.0 30.0 1 PMID:16653065 -1.1.1.206 * hyoscyamus albus 0.6 0.6 1 PMID:16653065 -1.1.1.206 * hyoscyamus bohemicus 1.2 1.2 1 PMID:16653065 -1.1.1.206 * hyoscyamus canariensis 7.5 7.5 1 PMID:16653065 -1.1.1.206 * hyoscyamus muticus 10.8 10.8 1 PMID:16653065 -1.1.1.206 * hyoscyamus niger 15.0 11.25 2 PMID:16653065 -1.1.1.206 * hyoscyamus pusillus 10.2 10.2 1 PMID:16653065 -1.1.1.206 * physalis edulis 54.0 54.0 1 PMID:16653065 -1.1.1.206 * physalis philadelphica 66.0 66.0 1 PMID:16653065 -1.1.1.206 * physochlaina orientalis 3.0 3.0 1 PMID:16653065 -1.1.1.206 * pseudomonas sp. 63.82 32.068 2 * -1.1.1.209 * homo sapiens 0.0253 0.0063 3 PMID:9415401 -1.1.1.209 * mus musculus 0.27 0.27 1 PMID:2691507 -1.1.1.21 * bos taurus 333.3 1.2 9 PMID:10990;PMID:15998238;PMID:20452228;PMID:24019949;PMID:25528584;PMID:4216364;PMID:6391552;PMID:6426471;PMID:7626055 -1.1.1.21 * cyberlindnera jadinii 37.0 0.024 3 PMID:4381350 -1.1.1.21 * debaryomyces nepalensis 80.0 80.0 1 * -1.1.1.21 * euonymus japonicus 5.24 5.24 1 PMID:16664750 -1.1.1.21 * galdieria sulphuraria 17.1 17.1 1 PMID:12223702 -1.1.1.21 * homo sapiens 13.6 5.3 7 PMID:15967436;PMID:1815509;PMID:1901806;PMID:25528584;PMID:4402695;PMID:6773519;PMID:6815419 -1.1.1.21 * rattus norvegicus 19.2 10.2 2 PMID:15967436 -1.1.1.21 * sungouiella intermedia 26.8 12.1 3 PMID:10681056 -1.1.1.21 * thermoanaerobacterium saccharolyticum 6.8 6.8 1 PMID:27849176 -1.1.1.21 * yamadazyma tenuis 28.64 15.07 2 PMID:9307017 -1.1.1.210 * ovis aries 0.0096 0.00835 2 PMID:2605227;PMID:3483295 -1.1.1.211 * homo sapiens 30.4 15.65 4 PMID:1550553 -1.1.1.212 * persea americana 0.0098 0.0098 1 PMID:7075600 -1.1.1.213 * mesocricetus auratus 26.8 6.2 5 PMID:2317205 -1.1.1.213 * rattus norvegicus 9540.0 1.55 13 PMID:10625484;PMID:15134457;PMID:16113996;PMID:17475203;PMID:18251511;PMID:1898369;PMID:3479982;PMID:6435601;PMID:8939970 -1.1.1.214 * candida parapsilosis 23.6 19.3 3 PMID:14593510;PMID:23828603 -1.1.1.215 * acetobacter ascendens 187.0 187.0 1 * -1.1.1.215 * acetobacter pasteurianus 336.0 336.0 1 * -1.1.1.215 * brevibacterium ketosoreductum 22.2 22.2 1 PMID:9501529 -1.1.1.215 * gluconacetobacter liquefaciens 61.03 61.03 1 * -1.1.1.215 * gluconobacter frateurii 137.0 137.0 1 PMID:17720837 -1.1.1.215 * pseudomonas plecoglossicida 90.71 90.71 1 PMID:30729393 -1.1.1.216 * aedes aegypti 9.7 9.35 2 PMID:19940247 -1.1.1.216 * persicaria minor 0.27 0.27 1 PMID:26600471 -1.1.1.217 * saccharomyces cerevisiae 0.9 0.45315 2 * -1.1.1.218 * cavia porcellus 0.9 0.86 3 PMID:2580834;PMID:3539118 -1.1.1.218 * mesocricetus auratus 0.21 0.21 1 PMID:10666297 -1.1.1.218 * oryctolagus cuniculus 0.43 0.43 1 PMID:9143356 -1.1.1.218 * pseudomonas putida 2.67 1.375 2 PMID:1701625 -1.1.1.219 * anthurium andraeanum 0.021 0.0014 5 * -1.1.1.219 * arabidopsis thaliana 0.0013 0.0007999999999999999 4 * -1.1.1.219 * camellia sinensis 42850.0 21446.4 2 * -1.1.1.219 * citrus sinensis 1.2e-05 1.2e-05 1 PMID:16524606 -1.1.1.219 * fragaria x ananassa 156.4 0.0013 6 PMID:20377227 -1.1.1.219 * ginkgo biloba 0.024 0.024 1 PMID:16664326 -1.1.1.219 * ipomoea nil 0.0015 0.0006 5 * -1.1.1.219 * lilium sp. 0.0013 0.0012 3 * -1.1.1.219 * matthiola incana 0.018 0.018 1 PMID:24241054 -1.1.1.219 * oryza sativa 0.349 0.1785 6 PMID:15863611 -1.1.1.219 * rosa hybrid cultivar 0.0013 0.0007 5 * -1.1.1.22 * capra hircus 342.9 342.9 1 * -1.1.1.22 * halobacterium salinarum 1.43e-06 1.43e-06 1 PMID:27527219 -1.1.1.22 * homo sapiens 0.69 0.001055 4 PMID:17209547;PMID:18930055 -1.1.1.22 * nicotiana tabacum 0.00299 0.00299 1 PMID:15821883 -1.1.1.22 * phaseolus vulgaris 27.17 27.17 1 PMID:8546701 -1.1.1.22 * saccharum spp. 2.17 2.17 1 PMID:12413493 -1.1.1.22 * streptococcus pyogenes 1.5 1.5 1 PMID:9013585 -1.1.1.220 * bos taurus 1.59e-05 1.59e-05 1 PMID:4004850 -1.1.1.220 * rattus norvegicus 49300.0 11.0000257 4 PMID:2656673;PMID:4004850 -1.1.1.224 * apium graveolens 3.93 3.76 3 PMID:16668806;PMID:9112783 -1.1.1.224 * phelipanche ramosa 0.12 0.014 3 PMID:12010466 -1.1.1.224 * striga hermonthica 0.008 0.008 1 * -1.1.1.225 * homo sapiens 0.008 0.008 1 PMID:2427522 -1.1.1.226 * sinomonas cyclohexanicum 104.1 40.0 3 PMID:3292236 -1.1.1.229 * torulaspora delbrueckii 0.649 0.3265 2 * -1.1.1.23 * [bacillus] caldolyticus 3.89 3.89 1 PMID:921748 -1.1.1.23 * asparagus officinalis 0.0009 0.0009 1 PMID:1989490 -1.1.1.23 * bacillus subtilis 3.89 3.725 2 PMID:921748 -1.1.1.23 * brassica oleracea 10.16 10.0 3 PMID:1586152;PMID:1989490 -1.1.1.23 * brassica oleracea var. capitata 0.0061 0.0061 1 PMID:1989490 -1.1.1.23 * cucumis sativus 0.0003 0.0003 1 PMID:1989490 -1.1.1.23 * escherichia coli 15.32 14.015 2 PMID:329890;PMID:7042909 -1.1.1.23 * geobacillus stearothermophilus 3.86 3.86 1 PMID:921748 -1.1.1.23 * lactuca sativa 0.0004 0.0004 1 PMID:1989490 -1.1.1.23 * mycobacterium tuberculosis 1.2 1.2 1 PMID:21672513 -1.1.1.23 * rosa sp. 0.0062 0.0062 1 PMID:1989490 -1.1.1.23 * salmonella enterica subsp. enterica serovar typhimurium 14.3 13.35 4 PMID:14275136;PMID:329890;PMID:3894023 -1.1.1.23 * solanum melongena 0.0004 0.0004 1 PMID:1989490 -1.1.1.23 * sporosarcina psychrophila 3.11 3.11 1 PMID:921748 -1.1.1.23 * triticum aestivum 0.0021 0.0021 1 PMID:1989490 -1.1.1.230 * rattus norvegicus 2e-05 2e-05 1 PMID:9821806 -1.1.1.231 * macaca fascicularis 24.3 6.08 5 PMID:11872167 -1.1.1.231 * oryctolagus cuniculus 19.9 19.9 1 PMID:6182444 -1.1.1.233 * flavobacterium sp. 545.0 340.0 3 PMID:1854199;PMID:3240988 -1.1.1.234 * columnea hybrida 0.0009 0.0009 1 * -1.1.1.234 * sinningia cardinalis 0.015 0.015 1 * -1.1.1.236 * datura inoxia 0.0145 0.0145 1 * -1.1.1.236 * datura stramonium 8.16 7.975 2 PMID:7765621 -1.1.1.236 * hyoscyamus niger 1.05 1.05 1 * -1.1.1.237 * coleus scutellarioides 4.52 4.52 1 PMID:15284489 -1.1.1.237 * wickerhamia fluorescens 727.0 727.0 1 PMID:21672638 -1.1.1.238 * clostridium paraputrificum 2.2 2.1 2 PMID:3167086 -1.1.1.239 * alcaligenes sp. 335.0 335.0 1 PMID:2997177 -1.1.1.239 * cavia porcellus 22.3 22.3 1 PMID:13781425 -1.1.1.239 * homo sapiens 0.00168 0.00106 2 PMID:11790346 -1.1.1.239 * ilyonectria destructans 84.6 84.6 1 PMID:2844744 -1.1.1.239 * mesocricetus auratus 4.2 4.2 1 PMID:2317205 -1.1.1.239 * notamacropus eugenii 0.0007 0.000438 2 PMID:11790346 -1.1.1.239 * phascolarctos cinereus 0.00283 0.00159 2 PMID:11790346 -1.1.1.239 * rattus norvegicus 0.01794 0.01794 1 PMID:11790346 -1.1.1.24 * klebsiella aerogenes 2.15 2.15 1 * -1.1.1.24 * neurospora crassa 86.87 86.87 1 PMID:148913 -1.1.1.24 * pinus taeda 3453.0 3453.0 1 * -1.1.1.24 * pseudonocardia sp. 3700.0 3700.0 1 PMID:9791947 -1.1.1.24 * rhodococcus rhodochrous 4800.0 4800.0 1 PMID:9791947 -1.1.1.24 * streptomyces sp. 3700.0 3700.0 1 PMID:9791947 -1.1.1.24 * vigna radiata var. radiata 29.99 29.99 1 * -1.1.1.240 * pseudomonas sp. 239.0 119.6325 2 * -1.1.1.241 * rhodococcus sp. (in: high g+c gram-positive bacteria) 1.08 0.8500000000000001 2 * -1.1.1.243 * rhodococcus erythropolis 1.46 0.0155 14 PMID:10473585;PMID:10832640 -1.1.1.244 * bacillus methanolicus 19.6 0.01 19 PMID:1510560;PMID:2280706;PMID:25596507;PMID:2673121 -1.1.1.244 * desulfitobacterium hafniense 0.0167 0.007 3 PMID:25596507 -1.1.1.244 * heyndrickxia coagulans 0.0155 0.0058 3 PMID:25596507 -1.1.1.244 * lysinibacillus fusiformis 0.0038 0.0038 2 PMID:25596507 -1.1.1.244 * lysinibacillus sphaericus 0.008 0.0029 3 PMID:25596507 -1.1.1.245 * acinetobacter sp. 0.28 0.28 1 PMID:1261 -1.1.1.245 * nocardia sp. 143.5 143.5 1 * -1.1.1.245 * pseudomonas sp. 2.5 1.35 4 * -1.1.1.245 * rhodococcus sp. (in: high g+c gram-positive bacteria) 127.0 127.0 1 * -1.1.1.245 * xanthobacter sp. 0.87 0.87 1 PMID:16346796 -1.1.1.25 * archaeoglobus fulgidus 1479.0 732.0 3 PMID:15336409;PMID:25524738 -1.1.1.25 * cucumis sativus 25.4 14.45 2 * -1.1.1.25 * escherichia coli 1100.0 19.9 3 PMID:26243542;PMID:3883995 -1.1.1.25 * fragaria x ananassa 184.0 184.0 3 PMID:20377227 -1.1.1.25 * mycobacterium tuberculosis 826.0 9.0 4 PMID:16202245;PMID:16298142;PMID:19463851 -1.1.1.25 * populus trichocarpa 103.0 103.0 1 PMID:29894016 -1.1.1.25 * solanum lycopersicum 0.28 0.28 1 * -1.1.1.25 * vigna mungo 167.0 167.0 1 PMID:620036 -1.1.1.250 * candida tropicalis 96.0 96.0 1 PMID:8250887 -1.1.1.252 * curvularia lunata 11.0 11.0 1 PMID:19010313 -1.1.1.252 * pyricularia grisea 18.4 18.4 1 PMID:8112349 -1.1.1.254 * agrobacterium sp. 14.15 14.15 1 PMID:9003445 -1.1.1.254 * agrobacterium sp. 525a 30.7 30.7 1 PMID:9214773 -1.1.1.255 * apium graveolens 6.08 1.9 5 PMID:1416989;PMID:7630943 -1.1.1.258 * acinetobacter sp. 0.03 0.03 1 PMID:1261 -1.1.1.26 * arabidopsis thaliana 7.28 7.28 1 * -1.1.1.26 * cyanophora paradoxa 0.134 0.096 5 PMID:16668760 -1.1.1.26 * homo sapiens 0.145 0.145 1 PMID:9463747 -1.1.1.26 * lathyrus oleraceus 0.738 0.16 5 PMID:16668760 -1.1.1.26 * nicotiana tabacum 9.1 7.35 2 PMID:13271335 -1.1.1.26 * pseudomonas fluorescens 7.0 6.0 2 PMID:236457 -1.1.1.26 * spinacia oleracea 0.3 0.05 3 PMID:16653027 -1.1.1.26 * thermococcus litoralis 44.5 44.5 1 PMID:11532010 -1.1.1.261 * aeropyrum pernix 3.22 3.22 1 PMID:11846799 -1.1.1.261 * methanothermobacter thermautotrophicus 314.0 157.04 2 PMID:8586635;PMID:9348086 -1.1.1.263 * ensifer adhaerens 530.0 70.5 12 PMID:16461673 -1.1.1.263 * mus musculus 3.01 3.01 1 PMID:18323634 -1.1.1.263 * sus scrofa 1.16 1.16 1 PMID:9504428 -1.1.1.264 * escherichia coli 0.05 0.045 2 PMID:9658018 -1.1.1.264 * gluconobacter oxydans 69.7 69.7 1 * -1.1.1.265 * saccharomyces cerevisiae 190.86 5.05 9 PMID:32967812;PMID:9327572 -1.1.1.267 * arabidopsis thaliana 5.6 3.8499999999999996 2 PMID:16972937 -1.1.1.267 * thermotoga maritima 5.0 4.0 2 PMID:20353826 -1.1.1.267 * zymomonas mobilis 19.5 19.5 1 PMID:11004410 -1.1.1.27 * acinetobacter calcoaceticus 27.6 27.6 1 * -1.1.1.27 * agama stellio stellio 53.0 53.0 1 PMID:12139477 -1.1.1.27 * cupriavidus necator 824.6 824.6 1 PMID:6825697 -1.1.1.27 * faxonius virilis 15.8 11.575 2 PMID:27544614 -1.1.1.27 * fundulus heteroclitus 419.0 419.0 1 PMID:6693386 -1.1.1.27 * heyndrickxia coagulans 2323.0 1337.0 2 PMID:24412354 -1.1.1.27 * homo sapiens 458.5 1.5585 10 PMID:1996957;PMID:25705126;PMID:7449128 -1.1.1.27 * ipomoea batatas 1.87 1.292 2 * -1.1.1.27 * lacticaseibacillus casei 2320.0 168.4 9 PMID:14601;PMID:29800600;PMID:823016 -1.1.1.27 * lactiplantibacillus plantarum 2350.0 2350.0 1 PMID:411654 -1.1.1.27 * lactobacillus acidophilus 2460.0 2460.0 1 PMID:411654 -1.1.1.27 * lactobacillus helveticus 2119.0 2119.0 1 PMID:9212432 -1.1.1.27 * lactobacillus sp. 203.3 203.3 1 PMID:18333614 -1.1.1.27 * lactococcus cremoris 9.3 9.3 1 PMID:24251099 -1.1.1.27 * lactococcus lactis 109.0 109.0 1 PMID:17595 -1.1.1.27 * latilactobacillus curvatus 2030.0 2030.0 1 PMID:14601 -1.1.1.27 * limosilactobacillus fermentum 144.8 80.64 2 * -1.1.1.27 * molinema dessetae 80.27 80.27 1 PMID:8897500 -1.1.1.27 * mus musculus 80.0 80.0 1 PMID:7144578 -1.1.1.27 * nocardia asteroides 216.9 216.9 1 PMID:1593962 -1.1.1.27 * oryctolagus cuniculus 30.0 30.0 1 PMID:17630768 -1.1.1.27 * plasmodium falciparum 453.8 353.4 2 PMID:15147206;PMID:18619439 -1.1.1.27 * plasmodium malariae 216.0 216.0 1 PMID:15147206 -1.1.1.27 * plasmodium ovale 215.0 215.0 1 PMID:15147206 -1.1.1.27 * plasmodium vivax 450.0 450.0 1 PMID:15147206 -1.1.1.27 * ruminococcaceae bacterium cpb6 29.6 20.0 2 PMID:33170386 -1.1.1.27 * saduria entomon 510.0 510.0 1 PMID:11007175 -1.1.1.27 * solanum tuberosum 18.5 18.5 1 PMID:4144124 -1.1.1.27 * staphylococcus epidermidis 2220.0 2220.0 1 PMID:242300 -1.1.1.27 * streptococcus uberis 1422.0 1422.0 1 PMID:3790089 -1.1.1.27 * taenia asiatica 456.0 456.0 1 PMID:18836746 -1.1.1.27 * thermoanaerobacter ethanolicus 589.0 589.0 1 PMID:1669451 -1.1.1.27 * thermoanaerobacterium saccharolyticum 0.65 0.38 2 PMID:25666131 -1.1.1.270 * homo sapiens 0.0432 0.023649999999999997 4 PMID:16455123 -1.1.1.270 * rattus norvegicus 0.0014 0.0014 1 PMID:6946726 -1.1.1.271 * sus scrofa 0.194 0.194 1 PMID:3338988 -1.1.1.273 * catharanthus roseus 0.0156 0.0156 1 * -1.1.1.273 * rauvolfia serpentina 0.0012 0.00108 2 * -1.1.1.273 * rauvolfia verticillata 0.0192 0.0192 1 * -1.1.1.273 * rauvolfia vomitoria 0.013 0.013 1 * -1.1.1.273 * vinca herbacea 0.00018 0.00018 1 * -1.1.1.273 * vinca minor 0.0006 0.0006 1 * -1.1.1.274 * corynebacterium sp. 3.38 1.6997499999999999 2 PMID:11563824;PMID:3597405 -1.1.1.274 * escherichia coli 64.4 2.21 23 PMID:11934293;PMID:16077126 -1.1.1.276 * agrobacterium tumefaciens 45.3 22.671499999999998 2 PMID:12092831;PMID:9028042 -1.1.1.276 * escherichia coli 2.4 1.20065 2 PMID:12092831;PMID:12535615 -1.1.1.276 * saccharomyces cerevisiae 6.0 6.0 1 PMID:12535615 -1.1.1.277 * digitalis lanata 0.00084 0.00057 2 * -1.1.1.279 * saccharomyces cerevisiae 1.958 1.958 1 PMID:3280313 -1.1.1.28 * lactiplantibacillus plantarum subsp. plantarum 2.51 2.51 1 PMID:25217009 -1.1.1.28 * lactobacillus delbrueckii subsp. bulgaricus 1950.0 8.3 3 PMID:1610363;PMID:2044942;PMID:25217009 -1.1.1.28 * lactobacillus delbrueckii subsp. lactis 0.15 0.15 1 PMID:23932744 -1.1.1.28 * lactobacillus jensenii 3838.0 88.71 15 * -1.1.1.28 * leuconostoc mesenteroides subsp. mesenteroides 4990.0 4450.0 3 PMID:22975125 -1.1.1.28 * limosilactobacillus reuteri 83.2 83.2 1 PMID:30129993 -1.1.1.28 * pediococcus acidilactici 422.0 281.0 2 PMID:22261863 -1.1.1.28 * pediococcus pentosaceus 835.0 475.5 2 PMID:22484960 -1.1.1.28 * rhodopseudomonas palustris 13.5 13.5 1 PMID:15056881 -1.1.1.28 * sporolactobacillus inulinus 7.5 7.5 1 PMID:26398356 -1.1.1.28 * sporolactobacillus laevolacticus 24.0 24.0 1 * -1.1.1.28 * staphylococcus epidermidis 10.0 10.0 1 * -1.1.1.28 * staphylococcus sp. 1710.0 1710.0 1 PMID:16233312 -1.1.1.28 * thermodesulfatator indicus 30.2 30.2 1 PMID:27237045 -1.1.1.28 * treponema pallidum 5000.0 2503.5 2 PMID:32963009 -1.1.1.280 * saccharomyces cerevisiae 0.411 0.411 1 PMID:3280313 -1.1.1.282 * larix sibirica 0.0664 0.0664 1 * -1.1.1.282 * pinus sylvestris 0.00391 0.00387 2 * -1.1.1.283 * aspergillus niger 7.77 4.3 2 PMID:3276516 -1.1.1.283 * cyberlindnera mrakii 48.9 48.9 1 * -1.1.1.283 * kluyveromyces marxianus 6.9 3.25 12 PMID:26223585 -1.1.1.283 * leishmania major 0.0053 0.0053 1 PMID:19076214 -1.1.1.283 * methanocaldococcus jannaschii 0.73 0.73 1 PMID:28644554 -1.1.1.283 * saccharomyces cerevisiae 8.38 8.365 2 PMID:12722185;PMID:3896793 -1.1.1.283 * synechococcus sp. 1.278 0.3685 18 PMID:16804176 -1.1.1.283 * trypanosoma brucei 0.0094 0.0094 1 PMID:19076214 -1.1.1.283 * trypanosoma cruzi 0.0048 0.0048 1 PMID:19076214 -1.1.1.284 * [candida] boidinii 47.9 38.3 3 PMID:1248477;PMID:2177826;PMID:4709506;PMID:6292667 -1.1.1.284 * arabidopsis thaliana 15.0 0.043 7 PMID:12913179;PMID:23201478 -1.1.1.284 * homo sapiens 3.2 0.0012 7 PMID:17632320;PMID:18224440;PMID:4332837;PMID:4373474;PMID:7329309 -1.1.1.284 * komagataella pastoris 2090.0 1050.1 2 PMID:6830251 -1.1.1.284 * lathyrus oleraceus 2.78 2.78 1 PMID:574372 -1.1.1.284 * ogataea angusta 27.0 14.5 4 PMID:17098416;PMID:17565589 -1.1.1.284 * pseudomonas putida 185.0 185.0 1 * -1.1.1.284 * rattus norvegicus 0.092 0.092 1 PMID:4332837 -1.1.1.284 * saccharomyces cerevisiae 0.64 0.64 1 * -1.1.1.284 * schwanniomyces vanrijiae 184.0 184.0 1 * -1.1.1.284 * zea mays 4.68 4.68 1 PMID:10213000 -1.1.1.287 * gluconobacter oxydans 68.5 12.0 10 PMID:16165327;PMID:19629658 -1.1.1.289 * candida albicans 145.0 33.1 3 PMID:16134116 -1.1.1.289 * gluconobacter oxydans 77.0 77.0 1 * -1.1.1.29 * arabidopsis thaliana 0.0051 0.0051 1 PMID:23860243 -1.1.1.29 * hyphomicrobium methylovorum 1086.0 1086.0 1 PMID:2114287 -1.1.1.292 * ensifer adhaerens 484.0 386.45 2 PMID:16461673 -1.1.1.298 * bacillus cereus 8.8 8.75 2 PMID:19517068 -1.1.1.298 * chloroflexus aurantiacus 10.0 0.04 3 PMID:21723339;PMID:8354269 -1.1.1.298 * metallosphaera sedula 200.0 100.75 2 PMID:18079405;PMID:19684143 -1.1.1.299 * flavobacterium frigidimaris 176.0 176.0 1 PMID:16306697 -1.1.1.299 * methanothermobacter thermautotrophicus 60.0 26.5 4 PMID:9639601 -1.1.1.3 * arabidopsis thaliana 18.87 12.135000000000002 2 PMID:11812230 -1.1.1.3 * bacillus subtilis 1.48 1.48 1 PMID:33046675 -1.1.1.3 * chenopodium quinoa 0.0044 0.0044 1 PMID:18006325 -1.1.1.3 * glycine max 13.0 13.0 1 PMID:19897476 -1.1.1.3 * lathyrus oleraceus 2.8 2.8 1 * -1.1.1.3 * ricinus communis 6.8 6.8 1 * -1.1.1.3 * saccharomyces cerevisiae 51.0 37.35 2 PMID:11341914;PMID:1897932 -1.1.1.3 * thermotoga maritima 66.5 66.5 1 PMID:30175674 -1.1.1.3 * thermus thermophilus 23.0 23.0 1 PMID:30423116 -1.1.1.3 * triticum aestivum 0.17 0.17 1 * -1.1.1.3 * zea mays 360.0 351.5 2 PMID:762132 -1.1.1.30 * acidovorax sp. 300.0 186.0 2 PMID:16233594 -1.1.1.30 * bacillus cereus 21.0 21.0 1 PMID:4197242 -1.1.1.30 * bos taurus 145.0 12.17 8 PMID:3355176;PMID:3986202;PMID:4633355;PMID:718894;PMID:7213590;PMID:7686368;PMID:8679568 -1.1.1.30 * camelus dromedarius 0.09 0.09 1 PMID:11742753 -1.1.1.30 * cereibacter sphaeroides 19.2 19.2 1 PMID:6981412 -1.1.1.30 * homo sapiens 0.8 0.6 5 PMID:8679568 -1.1.1.30 * mycolicibacterium phlei 14.0 14.0 1 PMID:24083 -1.1.1.30 * paracoccus denitrificans 97.0 97.0 1 * -1.1.1.30 * ralstonia pickettii 1200.0 360.0 5 PMID:16935252;PMID:19219638 -1.1.1.30 * rattus norvegicus 91.0 1.205 10 PMID:1804504;PMID:3355176;PMID:7213714;PMID:7686368;PMID:8487494 -1.1.1.30 * staphylococcus xylosus 0.74 0.74 1 PMID:7526614 -1.1.1.30 * zoogloea ramigera i-16-m 123.0 123.0 1 PMID:7240131 -1.1.1.300 * bacillus cereus 0.461 0.2985 2 PMID:27107124 -1.1.1.300 * homo sapiens 0.63 0.63 1 PMID:14674758 -1.1.1.301 * bacillus methanolicus 0.05 0.05 1 PMID:31417519 -1.1.1.302 * methanocaldococcus jannaschii 0.0008 0.0008 1 PMID:16730025 -1.1.1.304 * bacillus licheniformis 120.0 120.0 1 PMID:26494135 -1.1.1.304 * geobacillus stearothermophilus 71.4 71.4 1 PMID:8879540 -1.1.1.304 * klebsiella pneumoniae 79.0 79.0 1 * -1.1.1.304 * paenibacillus polymyxa 72.6 72.6 1 PMID:23701367 -1.1.1.306 * amycolatopsis methanolica 15.0 0.23 5 PMID:1597190;PMID:9202149 -1.1.1.306 * mycolicibacterium smegmatis 22.64 22.64 1 PMID:12809551 -1.1.1.307 * candida tropicalis 251.5 127.18 2 PMID:19557353;PMID:21922311 -1.1.1.307 * chlorella sorokiniana 0.027 0.024 2 PMID:25342968 -1.1.1.307 * debaryomyces nepalensis 50.2 50.2 1 PMID:33143604 -1.1.1.307 * neurospora crassa 35.7 29.05 2 PMID:33618706 -1.1.1.307 * scheffersomyces stipitis 23.2 13.2 6 PMID:19330484;PMID:33618706;PMID:3921014 -1.1.1.307 * spathaspora arborariae 5.12 0.455 3 * -1.1.1.307 * yamadazyma tenuis 20.64 20.64 1 PMID:9307017 -1.1.1.308 * cupriavidus pinatubonensis 4.74 4.74 1 PMID:20150239 -1.1.1.31 * bacillus cereus 8.77 8.735 4 PMID:19517068 -1.1.1.31 * diutina rugosa 36.1 36.1 1 PMID:8988636 -1.1.1.31 * homo sapiens 0.0046 0.0042 3 PMID:16466957 -1.1.1.31 * oryctolagus cuniculus 10.7 10.7 1 PMID:3335502 -1.1.1.31 * pseudomonas denitrificans (nom. rej.) 58.67 30.145 2 * -1.1.1.31 * pseudomonas putida 294.0 294.0 1 PMID:8988636 -1.1.1.31 * sus scrofa 20.9 20.9 1 PMID:13416257 -1.1.1.310 * chromohalobacter israelensis 675.0 7.4 3 PMID:20007648 -1.1.1.311 * azoarcus sp. 3.8 3.8 1 PMID:11479712 -1.1.1.312 * phytopseudomonas straminea 549.0 274.7065 2 PMID:15277747;PMID:26671 -1.1.1.312 * sphingomonas paucimobilis 360.0 360.0 1 PMID:11073908 -1.1.1.315 * homo sapiens 124000.0 52500.0 4 PMID:10369264;PMID:26391396 -1.1.1.316 * spinacia oleracea 2.17 2.17 3 PMID:15509850 -1.1.1.316 * ulva compressa 25.5 20.95 2 PMID:22153245 -1.1.1.318 * clarkia breweri 1.98 1.98 1 PMID:18208524 -1.1.1.319 * clarkia breweri 0.65 0.65 1 PMID:18208524 -1.1.1.324 * nepeta racemosa 1417.0 1417.0 1 PMID:7726550 -1.1.1.324 * rauvolfia serpentina 2.7 2.7 1 PMID:1864846 -1.1.1.328 * paenarthrobacter nicotinovorans 0.893 0.452 6 PMID:17293530 -1.1.1.331 * podophyllum peltatum 3500.0 3500.0 1 PMID:16493463 -1.1.1.334 * erythroxylum coca 0.0002669 0.0002669 1 PMID:22665766 -1.1.1.337 * paracoccus pantotrophus 2.52 2.52 1 PMID:15758220 -1.1.1.34 * arabidopsis thaliana 0.03568 0.027585000000000002 2 PMID:31275031 -1.1.1.34 * fusarium oxysporum 0.145 0.145 1 PMID:26407 -1.1.1.34 * haloferax volcanii 24000.0 12000.345 2 PMID:16969709;PMID:8550415 -1.1.1.34 * homarus americanus 60.0 30.0003 2 PMID:15086315 -1.1.1.34 * leishmania major 0.0335 0.0335 1 PMID:10861207 -1.1.1.34 * nepeta cataria 0.003 0.003 1 * -1.1.1.34 * rattus norvegicus 0.03 0.02235 2 PMID:237546;PMID:4985697 -1.1.1.34 * saccharolobus solfataricus 17500.0 11.2 4 PMID:10600463;PMID:10694393;PMID:9171410 -1.1.1.34 * saccharomyces cerevisiae 0.0035 0.0035 1 PMID:13818862 -1.1.1.34 * schistosoma mansoni 0.0036 0.0036 1 PMID:1905241 -1.1.1.34 * solanum tuberosum 7800.0 7800.0 1 PMID:12834277 -1.1.1.34 * streptomyces sp. 1.6 1.6 1 PMID:9973353 -1.1.1.34 * trypanosoma cruzi 28.0 14.0082 2 PMID:11801242;PMID:9521823 -1.1.1.342 * salmonella enterica subsp. enterica serovar typhi 93.0 93.0 1 PMID:9538012 -1.1.1.343 * bradyrhizobium sp. 31.16 15.6245 2 * -1.1.1.343 * leuconostoc lactis 1.6 1.6 1 PMID:8829540 -1.1.1.343 * leuconostoc mesenteroides subsp. cremoris 0.1 0.1 1 PMID:8829540 -1.1.1.343 * leuconostoc mesenteroides subsp. dextranicum 1.7 1.7 1 PMID:8829540 -1.1.1.343 * leuconostoc mesenteroides subsp. mesenteroides 1.3 1.3 1 PMID:8829540 -1.1.1.343 * leuconostoc sp. 4.4 4.2 2 PMID:8829540 -1.1.1.343 * levilactobacillus brevis 0.1 0.1 1 PMID:8829540 -1.1.1.343 * methylobacillus flagellatus 4.0 0.67 3 PMID:10658669 -1.1.1.343 * moniliella megachiliensis 4.3 4.3 1 PMID:19804861 -1.1.1.343 * weissella paramesenteroides 1.9 1.9 1 PMID:8829540 -1.1.1.343 * weissella viridescens 1.5 1.5 1 PMID:8829540 -1.1.1.345 * enterococcus faecalis 3.7 3.1500000000000004 2 PMID:11823242 -1.1.1.345 * haloferax mediterranei 1.462 0.799 3 PMID:11120357 -1.1.1.345 * lactiplantibacillus plantarum 170.0 86.1 2 PMID:1840590 -1.1.1.346 * brevibacterium ketosoreductum 22.2 11.135 2 PMID:9501529 -1.1.1.346 * corynebacterium glutamicum 0.308 0.2375 6 PMID:23356419 -1.1.1.346 * corynebacterium sp. 3.38 0.9973000000000001 4 PMID:3597405 -1.1.1.346 * escherichia coli 6.3 6.3 1 PMID:11934293 -1.1.1.347 * carpoglyphus lactis 31.0 15.508 2 PMID:18422649 -1.1.1.347 * castellaniella defragrans 4.33 4.33 1 PMID:22286981 -1.1.1.348 * medicago sativa 461.1 230.675 2 PMID:8071365 -1.1.1.35 * bos taurus 6.0 6.0 1 PMID:13163047 -1.1.1.35 * clostridium kluyveri 0.41 0.41 1 * -1.1.1.35 * cupriavidus necator 16.5 9.0 2 PMID:25401070 -1.1.1.35 * escherichia coli 20.0 20.0 1 PMID:7012144;PMID:7024730 -1.1.1.35 * euglena gracilis 40.0 40.0 1 PMID:12586899 -1.1.1.35 * ferroglobus placidus 0.5 0.5 1 PMID:25630364 -1.1.1.35 * homo sapiens 1200.0 0.087 7 PMID:10231530;PMID:10329704;PMID:9553139 -1.1.1.35 * metallosphaera sedula 3.0 3.0 1 PMID:21169482 -1.1.1.35 * mycolicibacterium smegmatis 41.2 41.2 1 PMID:521433 -1.1.1.35 * neurospora crassa 23.4 23.4 1 PMID:1830048 -1.1.1.35 * rattus norvegicus 565.0 2.77 13 PMID:15358356;PMID:2042025;PMID:6773478;PMID:7150615;PMID:9003397 -1.1.1.35 * sus scrofa 511.0 198.0 4 PMID:1121273;PMID:4700451;PMID:6378901;PMID:9593854 -1.1.1.351 * methylobacillus flagellatus 0.67 0.37 2 * -1.1.1.351 * pseudomonas fluorescens 0.121 0.072 2 PMID:6402366 -1.1.1.352 * aspergillus parasiticus 0.0222 0.011116000000000001 2 PMID:14602595 -1.1.1.352 * levilactobacillus brevis 0.552 0.279065 2 PMID:18323645 -1.1.1.353 * aspergillus parasiticus 0.052 0.027 3 PMID:16349333 -1.1.1.354 * carpoglyphus lactis 31.0 31.0 1 PMID:18422649 -1.1.1.357 * comamonas testosteroni 15.4 9.67 2 PMID:25913427 -1.1.1.358 * candida dubliniensis 49.1 35.55 2 * -1.1.1.358 * candida parapsilosis 251.0 212.0 2 PMID:2644973 -1.1.1.359 * saccharolobus solfataricus 437.0 437.0 1 PMID:3827812 -1.1.1.359 * thermoplasma acidophilum 458.0 389.0 2 PMID:2803257;PMID:8436115 -1.1.1.36 * candida tropicalis 125.0 125.0 1 PMID:10497229 -1.1.1.36 * candidatus accumulibacter phosphatis 14.0 0.61 5 PMID:33122026 -1.1.1.36 * cupriavidus necator 0.53 0.53 1 PMID:17609944 -1.1.1.36 * homo sapiens 0.091 0.048 13 PMID:10497229;PMID:10671535 -1.1.1.36 * methylorubrum extorquens 184.0 184.0 1 * -1.1.1.36 * methylorubrum rhodesianum 771.0 585.5 2 * -1.1.1.36 * mycolicibacterium smegmatis 0.025 0.025 1 PMID:28126742 -1.1.1.36 * pigeon 250.0 170.1 3 PMID:14004466 -1.1.1.36 * rattus norvegicus 45.2 4.79 4 PMID:3516072;PMID:9003397 -1.1.1.36 * saccharomyces cerevisiae 1.3 0.9 3 PMID:10497229 -1.1.1.36 * streptococcus equi 1.23 1.23 1 PMID:16292535 -1.1.1.36 * syntrophomonas wolfei 10.6 7.71 2 * -1.1.1.36 * zoogloea ramigera 608.0 412.0 3 PMID:20866;PMID:3286259;PMID:3542050 -1.1.1.360 * picrophilus oshimae 252.0 252.0 1 PMID:15691337 -1.1.1.360 * thermoplasma volcanium 498.0 498.0 2 PMID:24816096 -1.1.1.363 * leuconostoc mesenteroides 715.0 715.0 1 PMID:1304341 -1.1.1.363 * pseudomonas aeruginosa 145.7 145.7 1 PMID:28986240 -1.1.1.363 * pseudomonas putida 0.103 0.0165 4 PMID:26702395 -1.1.1.365 * aspergillus niger 8.7 2.055 6 PMID:18768163 -1.1.1.365 * euglena gracilis 0.671 0.33761 2 PMID:17090924 -1.1.1.368 * thauera aromatica 11.8 11.8 1 PMID:10406950 -1.1.1.37 * [bacillus] caldotenax 83.0 83.0 1 * -1.1.1.37 * ananas comosus 2000.0 1747.0 2 * -1.1.1.37 * archaeoglobus fulgidus 4799.0 2400.32 2 PMID:9211715 -1.1.1.37 * bacillus sp. (in: firmicutes) 187.0 187.0 1 * -1.1.1.37 * bacillus subtilis 322.0 322.0 1 * -1.1.1.37 * badhamia polycephala 1020.0 810.0 3 PMID:4355490;PMID:945747 -1.1.1.37 * beggiatoa leptomitoformis 20.43 20.43 1 * -1.1.1.37 * bos taurus 41.75 41.75 1 PMID:5935348 -1.1.1.37 * bradyrhizobium japonicum 1270.0 1270.0 1 * -1.1.1.37 * canis lupus familiaris 1200.0 1200.0 1 PMID:190515 -1.1.1.37 * ceratonia siliqua 188.0 188.0 1 PMID:22965554 -1.1.1.37 * cereibacter sphaeroides 14.7 11.0 3 PMID:19747101 -1.1.1.37 * coccochloris peniocystis 110.4 110.4 1 * -1.1.1.37 * comamonas testosteroni 2.762 2.762 1 PMID:238957 -1.1.1.37 * corynebacterium glutamicum 517.0 517.0 1 PMID:16233457 -1.1.1.37 * dictyostelium discoideum 550.0 550.0 1 PMID:7142959 -1.1.1.37 * drosophila virilis 1670.0 1670.0 1 PMID:4313528 -1.1.1.37 * echinococcus granulosus 238.1 238.1 1 PMID:15383291 -1.1.1.37 * escherichia coli 1920.0 1920.0 1 * -1.1.1.37 * flavobacterium frigidimaris 176.0 176.0 1 PMID:16306697 -1.1.1.37 * glaesserella parasuis 222.0 222.0 1 PMID:9244395 -1.1.1.37 * glycine max 1675.0 1675.0 1 * -1.1.1.37 * halobacterium salinarum 104.0 104.0 1 PMID:901751 -1.1.1.37 * heliocidaris crassispina 1.28 1.28 1 PMID:6469942 -1.1.1.37 * homo sapiens 46.5 46.5 1 PMID:6625603 -1.1.1.37 * macromonas bipunctata 26.9 26.9 1 * -1.1.1.37 * mesembryanthemum cordifolium 1740.0 1740.0 1 * -1.1.1.37 * methanospirillum hungatei 62.0 31.62 2 PMID:35274;PMID:7305925 -1.1.1.37 * methylosinus trichosporium 187.8 133.0 2 PMID:27682078 -1.1.1.37 * methylotuvimicrobium alcaliphilum 20.75 17.9 2 PMID:27682078 -1.1.1.37 * mycolicibacterium phlei 43.47 43.47 1 PMID:922015 -1.1.1.37 * pyrobaculum islandicum 470.0 310.0 5 PMID:17487443 -1.1.1.37 * rasamsonia emersonii 1610.0 1610.0 1 PMID:15265031 -1.1.1.37 * rattus norvegicus 68.0 68.0 1 PMID:1898089 -1.1.1.37 * rhodobacter capsulatus 348.0 174.8 2 PMID:3114237 -1.1.1.37 * rhodocyclus purpureus 1.773 1.773 1 PMID:3114237 -1.1.1.37 * rhodomicrobium vannielii 868.0 868.0 1 PMID:3114237 -1.1.1.37 * rhodopseudomonas palustris 1.61 1.58 2 PMID:16827662 -1.1.1.37 * rhodospirillum rubrum 2.324 2.324 1 PMID:3114237 -1.1.1.37 * solanum lycopersicum 108.0 108.0 1 * -1.1.1.37 * sulfolobus acidocaldarius 277.0 139.25 2 PMID:3109450 -1.1.1.37 * sus scrofa 182.0 146.0 2 PMID:21114258;PMID:215188 -1.1.1.37 * syntrophobacter fumaroxidans 1728.0 1728.0 1 PMID:8900056 -1.1.1.37 * taenia solium 409.0 205.8075 4 PMID:19277715;PMID:21439955 -1.1.1.37 * thermoplasma acidophilum 180.0 180.0 1 PMID:3741624 -1.1.1.37 * thermus aquaticus 100.5 100.5 1 * -1.1.1.37 * thermus thermophilus 2600.0 2600.0 1 PMID:24386145 -1.1.1.37 * trichomonas vaginalis 352.7 352.7 1 PMID:9269720 -1.1.1.37 * vigna mungo 199.0 199.0 1 * -1.1.1.37 * vulcanithermus mediatlanticus 6.94 5.970000000000001 2 PMID:16266275 -1.1.1.37 * zea mays 533000.0 2345.0 4 * -1.1.1.376 * azospirillum brasilense 44.9 14.850000000000001 12 PMID:16326697 -1.1.1.376 * haloferax volcanii 376.0 349.5 2 PMID:32055827 -1.1.1.377 * thermoplasma acidophilum 36.2 35.1 3 PMID:22481639 -1.1.1.378 * azotobacter vinelandii 163.0 27.17 8 PMID:18505728 -1.1.1.378 * sphingomonas sp. 39.8 31.7 3 PMID:19187228 -1.1.1.379 * rhodotorula graminis 67.6 67.6 1 * -1.1.1.379 * schleiferilactobacillus harbinensis 1200.0 1200.0 1 PMID:29460618 -1.1.1.38 * agrobacterium tumefaciens 65.0 65.0 1 PMID:96110 -1.1.1.38 * amaranthus cruentus 0.58 0.52 2 PMID:12461129 -1.1.1.38 * ascaris suum 38.5 35.0 3 PMID:3741834;PMID:8117666;PMID:9179290;PMID:96110 -1.1.1.38 * citrobacter freundii 93.0 93.0 1 PMID:96110 -1.1.1.38 * clostridium tetanomorphum 7.0 7.0 1 PMID:96110 -1.1.1.38 * erwinia aroidea 30.0 30.0 1 PMID:96110 -1.1.1.38 * escherichia coli 1.7 0.885 2 PMID:225306 -1.1.1.38 * escherichia coli b 2.3 2.3 1 PMID:96110 -1.1.1.38 * escherichia coli k-12 9.0 9.0 1 PMID:96110 -1.1.1.38 * escherichia coli w 177.0 92.55 2 PMID:4144085;PMID:96110 -1.1.1.38 * klebsiella aerogenes 32.0 18.75 2 PMID:8117666;PMID:96110 -1.1.1.38 * lactiplantibacillus plantarum 3900.0 2035.0 2 PMID:14917678;PMID:4732222 -1.1.1.38 * leuconostoc mesenteroides 17.5 17.5 1 PMID:4732222 -1.1.1.38 * portulaca oleracea 0.107 0.036 3 PMID:15169944 -1.1.1.38 * proteus vulgaris 70.0 70.0 1 PMID:96110 -1.1.1.38 * saccharomyces cerevisiae 0.2 0.2 1 PMID:4144229 -1.1.1.38 * sinorhizobium meliloti 0.545 0.3105 2 PMID:8387144;PMID:9043124 -1.1.1.381 * escherichia coli 2.4 2.4 1 PMID:12535615 -1.1.1.381 * saccharomyces cerevisiae 6.0 6.0 1 PMID:12535615 -1.1.1.386 * ips pini 0.52 0.092 5 PMID:22101251;PMID:26953347 -1.1.1.387 * pyrobaculum calidifontis 3.48 3.48 1 PMID:29353380 -1.1.1.388 * haloferax volcanii 42.0 42.0 1 PMID:25836736 -1.1.1.39 * brevundimonas diminuta 5.45 2.74 3 PMID:18460807 -1.1.1.39 * clupea harengus 36.09 20.17 4 PMID:23313742 -1.1.1.39 * crassula argentea 81.5 58.45 2 PMID:16663114;PMID:3597379 -1.1.1.39 * glossina morsitans 24.0 24.0 1 PMID:12751 -1.1.1.39 * portulaca oleracea 0.107 0.036 3 PMID:15169944 -1.1.1.39 * rhodopseudomonas palustris 64.0 64.0 1 PMID:20057150 -1.1.1.39 * sinorhizobium meliloti 45.2 45.2 1 PMID:10407149 -1.1.1.39 * sinorhizobium sp. 0.201 0.201 1 PMID:22307295 -1.1.1.39 * solanum tuberosum 72.5 72.5 1 PMID:7294802 -1.1.1.39 * tritrichomonas suis 20.5 20.5 1 PMID:8278219 -1.1.1.39 * zea mays 4.7 2.37 2 PMID:32540762 -1.1.1.391 * [clostridium] innocuum 3.2 3.2 1 PMID:2764572 -1.1.1.391 * blautia producta 2.49 1.56 8 PMID:2752021 -1.1.1.398 * rhodococcus sp. ad45 18.0 10.45 2 PMID:10094686 -1.1.1.399 * escherichia coli 9.7 6.484999999999999 2 PMID:8550422 -1.1.1.4 * bacillus licheniformis 1.193 0.046 14 * -1.1.1.4 * gluconobacter oxydans 0.6 0.6 1 PMID:25056 -1.1.1.4 * klebsiella aerogenes 270.0 270.0 1 PMID:2040298 -1.1.1.4 * lactococcus lactis 35.6 21.549999999999997 4 PMID:16348209 -1.1.1.4 * paenibacillus polymyxa 4.65 2.43 2 PMID:22961752;PMID:25056 -1.1.1.4 * paracoccus denitrificans 0.56 0.56 1 * -1.1.1.4 * pseudomonas aeruginosa 2.154 1.2625000000000002 8 PMID:30058099 -1.1.1.4 * saccharomyces cerevisiae 968.0 2.595 20 PMID:10938079;PMID:19507198;PMID:32556414 -1.1.1.4 * serratia marcescens 20.75 15.615 2 PMID:24981852 -1.1.1.40 * clarias gariepinus 0.008 0.008 1 PMID:23313742 -1.1.1.40 * clupea harengus 0.213 0.213 1 PMID:23313742 -1.1.1.40 * corynebacterium glutamicum 10.9 10.9 1 PMID:10877795 -1.1.1.40 * cyprinus carpio 0.045 0.045 1 PMID:23313742 -1.1.1.40 * escherichia coli 3.15 1.69 3 PMID:18045419;PMID:22068497 -1.1.1.40 * homo sapiens 91.4 56.35 5 PMID:1761063;PMID:19293334;PMID:1935931;PMID:7757881 -1.1.1.40 * mangifera indica 7910.0 7910.0 1 * -1.1.1.40 * mesembryanthemum cordifolium 30.14 30.14 1 * -1.1.1.40 * nicotiana tabacum 0.571 0.07050000000000001 8 PMID:18272530 -1.1.1.40 * oryza sativa 85.1 39.4 4 PMID:16290176;PMID:17516134 -1.1.1.40 * rattus norvegicus 41.0 41.0 1 PMID:1203253 -1.1.1.40 * rhodococcoides fascians 0.0023 0.0021 3 PMID:30372408 -1.1.1.40 * rhodococcus jostii 0.0435 0.022949999999999998 6 PMID:30372408 -1.1.1.40 * rhodococcus opacus 0.1533 0.1343 3 PMID:30372408 -1.1.1.40 * ricinus communis 18.2 18.2 1 PMID:15313216 -1.1.1.40 * saccharolobus solfataricus 36.6 36.6 1 PMID:3108257 -1.1.1.40 * salmo salar 0.026 0.026 1 PMID:23313742 -1.1.1.40 * salmo trutta 0.023 0.023 1 PMID:23313742 -1.1.1.40 * sinorhizobium meliloti 49.0 24.504 2 PMID:10407149;PMID:17071765 -1.1.1.40 * trichomonas vaginalis 199.0 199.0 1 PMID:15033531 -1.1.1.401 * sulfobacillus thermosulfidooxidans 4.06 4.06 3 PMID:25617114 -1.1.1.404 * sphingobium chlorophenolicum 2.1 2.1 1 PMID:19325743 -1.1.1.405 * haemophilus influenzae 2.87 1.8 2 PMID:10094675 -1.1.1.41 * acidithiobacillus thiooxidans 120.0 120.0 1 PMID:12204383 -1.1.1.41 * arabidopsis thaliana 0.169 0.169 1 * -1.1.1.41 * azotobacter vinelandii 75.5 75.5 1 PMID:15817777 -1.1.1.41 * campylobacter concisus 49.3 26.299999999999997 2 PMID:30876971 -1.1.1.41 * campylobacter sp. 53.2 30.950000000000003 2 PMID:25775177 -1.1.1.41 * candida tropicalis 21300.0 21300.0 1 * -1.1.1.41 * chlamydomonas reinhardtii 16.6 16.6 1 PMID:9733544 -1.1.1.41 * colwellia maris 50.5 50.5 1 PMID:15817777 -1.1.1.41 * cupriavidus necator 0.9 0.9 1 PMID:4404355 -1.1.1.41 * homo sapiens 22.0 21.85 2 PMID:14555658;PMID:16737955 -1.1.1.41 * lathyrus oleraceus 1.7 0.096 3 PMID:14507432 -1.1.1.41 * ostreococcus sp. 'lucimarinus' 72.3 38.05 2 PMID:25775177 -1.1.1.41 * phaeodactylum tricornutum 87.1 87.1 1 PMID:32824636 -1.1.1.41 * phycomyces blakesleeanus 48.9 43.2 2 PMID:8664264 -1.1.1.41 * rhodotorula toruloides 7.3 7.3 1 * -1.1.1.41 * sus scrofa 27.0 27.0 1 PMID:203934 -1.1.1.41 * trypanosoma brucei brucei 22.1 18.4 2 PMID:28642005 -1.1.1.41 * xylella fastidiosa 96.8 51.55 2 PMID:28220528 -1.1.1.41 * yarrowia lipolytica 22.0 0.165 4 PMID:15627396 -1.1.1.41 * zea mays 2.9 2.9 1 * -1.1.1.42 * archaeoglobus fulgidus 141.0 70.52 2 PMID:9325430 -1.1.1.42 * archaeoglobus lithotrophicus 0.01 0.01 1 * -1.1.1.42 * archaeoglobus profundus 0.01 0.01 1 * -1.1.1.42 * aspergillus niger 14.4 14.4 1 PMID:3753466 -1.1.1.42 * caldococcus noboribetus 144.0 144.0 1 PMID:9252109 -1.1.1.42 * chlorobium limicola 36.0 0.28 3 PMID:11952794 -1.1.1.42 * desulfobacter vibrioformis 202.2 202.2 1 PMID:9495015 -1.1.1.42 * fomitopsis palustris 75.0 75.0 1 PMID:12619682 -1.1.1.42 * haloferax volcanii 40.0 31.85 2 PMID:12007799;PMID:8593959 -1.1.1.42 * lathyrus oleraceus 27.2 0.072 3 PMID:14507432 -1.1.1.42 * leptolyngbya laminosa 500.0 500.0 1 PMID:10209282 -1.1.1.42 * moniliella megachiliensis 0.06 0.06 1 PMID:19804861 -1.1.1.42 * mus musculus 108.2 63.7 4 PMID:15254034 -1.1.1.42 * mycolicibacterium phlei 109.0 109.0 1 PMID:3448153 -1.1.1.42 * nicotiana tabacum 50.0 34.3 2 PMID:12232226 -1.1.1.42 * plasmodium falciparum 162.0 162.0 1 PMID:12694190 -1.1.1.42 * psychromonas marina 136.03 136.03 1 PMID:28447265 -1.1.1.42 * rattus norvegicus 3.0 3.0 1 PMID:16823514 -1.1.1.42 * rhodomicrobium vannielii 23.0 20.75 2 PMID:1935983 -1.1.1.42 * saccharolobus solfataricus 152.0 152.0 1 PMID:8593959 -1.1.1.42 * saccharopolyspora erythraea 0.75 0.75 1 PMID:12967008 -1.1.1.42 * spirodela polyrhiza 0.038 0.0213 2 * -1.1.1.42 * sus scrofa 38.6 36.45 4 PMID:11969425;PMID:12054490;PMID:14512428;PMID:15576556 -1.1.1.42 * synechocystis sp. 15.7 15.7 1 PMID:1730247 -1.1.1.42 * thermoleophilum minutum 3884.0 3884.0 1 * -1.1.1.42 * trypanosoma cruzi 219.0 143.0 2 PMID:21291916 -1.1.1.42 * vibrio parahaemolyticus 156.6 156.6 1 PMID:1295895 -1.1.1.42 * xylella fastidiosa 73.2 40.300000000000004 2 PMID:28220528 -1.1.1.42 * yarrowia lipolytica 0.3 0.26 3 PMID:15627396 -1.1.1.42 * zea mays 34.6 34.05 2 PMID:10847 -1.1.1.422 * arthrobacter sp. ts-15 160.12 5.41 23 PMID:31900306 -1.1.1.424 * haloarcula marismortui 100.0 100.0 1 PMID:15342590 -1.1.1.424 * haloferax volcanii 24.1 7.8 3 PMID:19584053;PMID:28854683 -1.1.1.425 * bacillus smithii 6.0 3.66 2 PMID:33208778 -1.1.1.425 * pseudarthrobacter phenanthrenivorans 17.8 0.73 3 PMID:30224354 -1.1.1.427 * saccharomyces cerevisiae 101.0 101.0 1 PMID:9920381 -1.1.1.429 * thauera aromatica 0.86 0.5700000000000001 2 PMID:34601806 -1.1.1.43 * [candida] boidinii 39.7 39.7 1 PMID:7350909 -1.1.1.43 * burkholderia cepacia 141.0 72.15 4 PMID:4154932;PMID:4402279 -1.1.1.43 * candida tropicalis 0.119 0.119 1 * -1.1.1.43 * lytechinus pictus 24.0 24.0 1 PMID:1639134 -1.1.1.43 * pseudomonas fluorescens 98.6 98.6 1 PMID:13894458 -1.1.1.43 * pseudomonas sp. 56.4 56.4 1 PMID:7350909 -1.1.1.43 * strongylocentrotus purpuratus 24.0 24.0 1 PMID:1639134 -1.1.1.43 * zea mays 20.8 20.8 1 PMID:16653162 -1.1.1.430 * candida parapsilosis 41.7 41.7 1 PMID:14532079 -1.1.1.430 * yamadazyma tenuis 7.12 7.12 1 * -1.1.1.431 * aspergillus niger 136.0 47.6 6 PMID:33842213 -1.1.1.431 * candida tropicalis 81.0 52.349999999999994 4 PMID:25214231 -1.1.1.431 * debaryomyces nepalensis 163.0 148.5 2 PMID:32356119 -1.1.1.431 * neurospora crassa 72.5 72.5 1 PMID:8620033 -1.1.1.431 * osmozyma mogii 0.48 0.48 1 PMID:16505992 -1.1.1.431 * saccharomyces cerevisiae 104.0 104.0 1 PMID:11481678 -1.1.1.431 * thermomyces lanuginosus 78.06 78.06 1 PMID:30831517 -1.1.1.431 * yamadazyma tenuis 0.16 0.16 1 PMID:19452479 -1.1.1.436 * acetobacterium woodii 9.5 5.275 4 PMID:35748623 -1.1.1.44 * [brevibacterium] flavum 175.0 165.5 2 * -1.1.1.44 * [candida] boidinii 39.7 39.7 1 PMID:31936 -1.1.1.44 * acer pseudoplatanus 80.0 79.75 2 * -1.1.1.44 * arthrobacter globiformis 25.7 25.7 1 * -1.1.1.44 * beta vulgaris 40.0 40.0 1 PMID:7773202 -1.1.1.44 * corynebacterium glutamicum 143.0 0.291 5 PMID:10848959;PMID:19399347 -1.1.1.44 * ctenopharyngodon idella 5.259 2.6380000000000003 2 PMID:24772981 -1.1.1.44 * cyberlindnera jadinii 48.0 37.65 4 PMID:236443;PMID:39514;PMID:8448161 -1.1.1.44 * enterococcus faecalis 14.47 14.47 1 PMID:236442;PMID:238996 -1.1.1.44 * escherichia coli 32.0 32.0 1 PMID:4401169;PMID:786365 -1.1.1.44 * gallus gallus 61.0 30.5885 2 PMID:15704497 -1.1.1.44 * geobacillus stearothermophilus 87.0 57.0 2 PMID:6292662 -1.1.1.44 * gryllus firmus 13.5 6.75845 2 PMID:24726622 -1.1.1.44 * homo sapiens 25.75 18.55 6 PMID:1128263;PMID:15558954;PMID:18237031;PMID:30098336;PMID:4151477 -1.1.1.44 * neurospora crassa 30.8 30.4 2 PMID:124005;PMID:4145008;PMID:4267298 -1.1.1.44 * oryctolagus cuniculus 22.0 21.0 2 PMID:3163 -1.1.1.44 * ovis aries 92.3 18.85 8 PMID:1504088;PMID:236441;PMID:4691505;PMID:4773872;PMID:7103051;PMID:9675070 -1.1.1.44 * phormidium sp. 38.0 38.0 1 * -1.1.1.44 * plasmodium falciparum 8.0 8.0 1 PMID:30098336 -1.1.1.44 * rattus norvegicus 32.0 7.7121 6 PMID:16284727;PMID:30506659;PMID:4401169;PMID:7623792;PMID:786365 -1.1.1.44 * ricinus communis 38.0 25.8 2 PMID:16660503 -1.1.1.44 * schizosaccharomyces pombe 39.4 39.4 1 PMID:10099784 -1.1.1.44 * sus scrofa 1.89 1.15 2 PMID:11218 -1.1.1.44 * trypanosoma cruzi 32.0 32.0 1 PMID:14698432 -1.1.1.443 * aspergillus terreus 0.03 0.03 1 PMID:3182756 -1.1.1.45 * drosophila melanogaster 63.8 21.0 3 PMID:37912;PMID:3926004;PMID:4328697 -1.1.1.45 * oryctolagus cuniculus 6.71 3.3605 2 PMID:15809331 -1.1.1.47 * bacillus sp. (in: firmicutes) 194.0 194.0 1 PMID:28587256 -1.1.1.47 * bacillus subtilis 368.0 197.0 2 PMID:21162;PMID:6415053 -1.1.1.47 * bos taurus 33.6 17.925 2 PMID:7092232;PMID:7553351 -1.1.1.47 * burkholderia cepacia 2000.0 2000.0 1 PMID:12573242 -1.1.1.47 * enterobacter asburiae 0.91 0.37 15 PMID:16121225 -1.1.1.47 * gluconacetobacter diazotrophicus 1.1 0.4 7 PMID:16479355 -1.1.1.47 * gluconobacter oxydans 140.0 140.0 1 * -1.1.1.47 * nostoc sp. 105.0 105.0 1 * -1.1.1.47 * oncorhynchus mykiss 6.2 4.9 2 PMID:4397856;PMID:7553351 -1.1.1.47 * priestia megaterium 550.0 550.0 1 PMID:2530 -1.1.1.47 * saccharolobus solfataricus 437.0 437.0 1 PMID:3827812 -1.1.1.47 * sulfurisphaera tokodaii 32.0 32.0 1 * -1.1.1.47 * sus scrofa 3.57 1.92 2 PMID:4392298;PMID:6641908 -1.1.1.47 * thermoplasma acidophilum 320.0 320.0 1 PMID:2803257 -1.1.1.47 * thermoproteus tenax 202.0 202.0 1 PMID:9238103 -1.1.1.48 * azotobacter vinelandii 390.0 325.0 2 PMID:16349292 -1.1.1.48 * caulobacter crescentus ae22 0.023 0.023 1 PMID:210153 -1.1.1.48 * caulobacter crescentus ae23 0.009 0.009 1 PMID:210153 -1.1.1.48 * caulobacter crescentus cb13 0.026 0.026 1 PMID:210153 -1.1.1.48 * pseudomonas fluorescens 849.0 29.0 7 PMID:16349292;PMID:1740135;PMID:4153311;PMID:6292657;PMID:6806150;PMID:8652621 -1.1.1.48 * pseudomonas sp. 0.06 0.06 1 PMID:14251301 -1.1.1.48 * rhizobium meliloti l5-30 272.0 0.078 9 PMID:16349292;PMID:3745118 -1.1.1.48 * roseateles saccharophilus 202.0 202.0 1 PMID:16349292;PMID:4149284 -1.1.1.48 * sinorhizobium meliloti 0.071 0.0392 2 PMID:3745118 -1.1.1.49 * arabidopsis thaliana 139.5 20.3 3 PMID:19631646 -1.1.1.49 * aspergillus aculeatus 220.0 220.0 1 PMID:16202239 -1.1.1.49 * aspergillus nidulans 745.0 745.0 1 PMID:8277259 -1.1.1.49 * aspergillus niger 790.0 790.0 1 PMID:8277259 -1.1.1.49 * bos taurus 2.221 0.916 3 PMID:25980795 -1.1.1.49 * camelus dromedarius 289.6 1.804 3 PMID:22538316;PMID:25610637 -1.1.1.49 * canis lupus familiaris 130.0 130.0 1 PMID:11849992 -1.1.1.49 * coriandrum sativum 1.83 1.83 1 * -1.1.1.49 * cryptococcus neoformans 50.0 50.0 1 PMID:8080277 -1.1.1.49 * deinococcus radiophilus 3078.0 1983.5 4 PMID:17846585 -1.1.1.49 * dictyostelium discoideum 54.1 54.1 1 * -1.1.1.49 * escherichia coli 104.0 100.0 3 PMID:4392411;PMID:4401601 -1.1.1.49 * fragaria x ananassa 36.3 29.25 2 PMID:20377227 -1.1.1.49 * homo sapiens 222.8 39.75 8 PMID:15202492;PMID:1540638;PMID:16934959;PMID:20346879;PMID:2270145;PMID:27053284 -1.1.1.49 * hordeum vulgare 2.15 2.15 1 PMID:12569406 -1.1.1.49 * koliella antarctica 0.346 0.346 1 PMID:23117891 -1.1.1.49 * meleagris gallopavo 44.16 44.16 1 PMID:22900294 -1.1.1.49 * meyerozyma guilliermondii 0.64 0.64 1 * -1.1.1.49 * moniliella megachiliensis 3.7 3.7 1 PMID:19804861 -1.1.1.49 * oncorhynchus mykiss 36.25 16.47 4 PMID:16335057 -1.1.1.49 * ovis aries 27.69 16.165 2 PMID:12530481 -1.1.1.49 * petroselinum crispum 2.15 2.15 1 PMID:12071647 -1.1.1.49 * pseudomonas aeruginosa 0.09 0.0675 2 PMID:18996187 -1.1.1.49 * pseudomonas fluorescens 0.098 0.0615 2 PMID:18996187 -1.1.1.49 * rattus norvegicus 480.0 32.8 6 PMID:15328887;PMID:21930213;PMID:30506659;PMID:7823774;PMID:9219438 -1.1.1.49 * sus scrofa 201.0 125.5 2 PMID:2270145 -1.1.1.49 * taenia crassiceps 67.6 50.699999999999996 2 PMID:18297308 -1.1.1.49 * thermotoga maritima 76.0 76.0 1 PMID:12814622 -1.1.1.49 * trypanosoma brucei 14.0 7.0035 2 PMID:10215021 -1.1.1.49 * zymomonas mobilis subsp. mobilis 852.0 584.1 2 PMID:29480380 -1.1.1.50 * bos taurus 0.15 0.15 1 PMID:1592159 -1.1.1.50 * comamonas testosteroni 119.0 21.4 8 PMID:10833462;PMID:17092593;PMID:25913427 -1.1.1.50 * digitalis lanata 2999.0 869.8 3 * -1.1.1.50 * gallus gallus 0.00024 0.00024 1 PMID:2278841 -1.1.1.50 * homo sapiens 76.1 0.0085 23 PMID:11294878;PMID:14672942;PMID:15383625;PMID:9188497;PMID:9415401 -1.1.1.50 * ictalurus punctatus 3.2e-07 2.7e-07 3 PMID:12589949 -1.1.1.50 * mus musculus 6.1 6.1 1 PMID:3170514 -1.1.1.50 * pseudomonas putida 63.0 43.3 2 * -1.1.1.50 * rattus norvegicus 2.2 0.2765 8 PMID:16168;PMID:17475203;PMID:2268552;PMID:2933398;PMID:3516149;PMID:9188497 -1.1.1.51 * homo sapiens 2.5 1.675e-08 4 PMID:11940569;PMID:9287397 -1.1.1.51 * periplaneta americana 2.165e-09 4.910000000000001e-10 6 PMID:9268626 -1.1.1.53 * oncorhynchus mykiss 1.57 1.57 1 PMID:10725344 -1.1.1.53 * sus scrofa 0.167 0.042499999999999996 18 PMID:1377683;PMID:2064995;PMID:3240999 -1.1.1.54 * nicotiana tabacum 0.11 0.11 1 PMID:11117876 -1.1.1.54 * pseudomonas putida 38.8 8.25 12 PMID:10347052 -1.1.1.56 * cereibacter sphaeroides 59.0 59.0 1 PMID:1527498 -1.1.1.56 * klebsiella aerogenes 23000.0 83.0 7 PMID:14427582;PMID:4376942;PMID:4618776 -1.1.1.56 * pantoea agglomerans 144.0 144.0 1 * -1.1.1.57 * escherichia coli 770.0 16.0 6 PMID:14401695;PMID:195622;PMID:4402996;PMID:6755169 -1.1.1.58 * escherichia coli 2730.0 198.0 4 PMID:14401695;PMID:6755169 -1.1.1.59 * bacillus cereus 8.77 8.77 1 PMID:19517068 -1.1.1.6 * cellulomonas sp. 138.0 128.0 3 PMID:19479208 -1.1.1.6 * escherichia coli 4.8 1.26 3 PMID:19189409;PMID:19725101;PMID:20585771 -1.1.1.6 * geotrichum candidum 41.2 41.2 1 PMID:7200090 -1.1.1.6 * klebsiella aerogenes 82.0 35.0 5 PMID:14417009;PMID:19352646;PMID:4364415;PMID:6988402 -1.1.1.6 * klebsiella pneumoniae 220.0 15.7 7 PMID:18682988;PMID:20585771;PMID:26115038;PMID:31635443 -1.1.1.6 * klebsiella pneumoniae subsp. pneumoniae 101.68 52.230000000000004 2 PMID:31635443 -1.1.1.6 * pichia membranifaciens 448.0 448.0 1 * -1.1.1.6 * priestia megaterium 58.1 58.1 1 * -1.1.1.6 * salmonella enterica 3.9 3.9 1 PMID:20585771 -1.1.1.6 * schizosaccharomyces pombe 9.3 0.049 3 PMID:20396879 -1.1.1.6 * thermotoga maritima 45.0 45.0 1 PMID:24664447 -1.1.1.6 * thermus thermophilus 18.5 18.5 1 PMID:19932956 -1.1.1.60 * pseudomonas putida 160.0 105.0 2 PMID:13900766;PMID:4300866 -1.1.1.61 * escherichia coli 9.0 0.1335 4 PMID:19372223 -1.1.1.62 * equus caballus 10.7 10.7 1 PMID:6584179 -1.1.1.62 * gallus gallus 289.0 289.0 1 PMID:6936398 -1.1.1.62 * homo sapiens 7.2 4.85 2 PMID:3855619;PMID:4155786 -1.1.1.62 * mus musculus 2.48 2.48 1 PMID:7737980 -1.1.1.62 * ovis aries 0.136 0.136 1 PMID:4314937 -1.1.1.64 * cavia porcellus 145.0 49.408 4 PMID:13696735;PMID:13781425;PMID:18133 -1.1.1.64 * rattus norvegicus 0.0033 0.0033 1 PMID:241882 -1.1.1.64 * sus scrofa 67.7 67.7 1 PMID:241882;PMID:4153029 -1.1.1.67 * [brevibacterium] flavum 0.243 0.0135 4 * -1.1.1.67 * absidia glauca 10.24 10.24 1 PMID:5111 -1.1.1.67 * aspergillus fumigatus 33.0 23.5 2 PMID:18983992 -1.1.1.67 * cereibacter sphaeroides 68.3 64.3 2 PMID:2789134;PMID:9274047 -1.1.1.67 * eimeria tenella 0.05 0.05 1 PMID:2538747 -1.1.1.67 * fructilactobacillus sanfranciscensis 15.48 15.48 1 PMID:12670693 -1.1.1.67 * gluconobacter oxydans 6.9 6.9 1 * -1.1.1.67 * leuconostoc mesenteroides 393.0 393.0 1 PMID:236430 -1.1.1.67 * leuconostoc pseudomesenteroides 450.0 450.0 1 PMID:12560988 -1.1.1.67 * levilactobacillus brevis 27.3 27.3 1 * -1.1.1.67 * pseudomonas fluorescens 63.0 46.0 3 PMID:19266906;PMID:9116029 -1.1.1.67 * thermotoga maritima 54.0 54.0 2 PMID:18719905 -1.1.1.69 * gluconobacter oxydans 200.0 69.69 3 PMID:15060755 -1.1.1.7 * oryctolagus cuniculus 0.3 0.3 1 PMID:13672935 -1.1.1.71 * acetivibrio thermocellus 2.7 1.3625 2 PMID:21825121 -1.1.1.71 * ralstonia sp. 362.6 9.07 16 PMID:23381774 -1.1.1.71 * starmerella magnoliae 12.9 4.11 4 PMID:32846049 -1.1.1.72 * aspergillus nidulans 24.1 24.1 1 PMID:2200840 -1.1.1.72 * aspergillus niger 32.5 32.5 1 PMID:2200840 -1.1.1.72 * aspergillus oryzae 1.034 0.5495 4 PMID:15073319 -1.1.1.72 * gluconobacter oxydans 87.1 80.5 3 PMID:20198657;PMID:20887732 -1.1.1.72 * lactiplantibacillus plantarum 0.0049 0.0049 1 * -1.1.1.72 * lactobacillus acidophilus 0.0131 0.0131 1 * -1.1.1.72 * lactobacillus delbrueckii 0.0043 0.0043 1 * -1.1.1.72 * neurospora crassa 20.7 20.7 1 * -1.1.1.72 * oryctolagus cuniculus 5.75 5.75 1 PMID:7144572 -1.1.1.73 * drosophila sp. (in: flies) 0.57 0.57 1 PMID:4636742 -1.1.1.73 * ogataea wickerhamii 91.1 45.5612 2 PMID:23274959 -1.1.1.75 * bacillus subtilis 0.001 0.001 1 PMID:4334917 -1.1.1.75 * escherichia coli 0.008 0.0055 2 PMID:5329339;PMID:5340733 -1.1.1.75 * pseudomonas sp. 8.5 0.4 3 PMID:4362743;PMID:5729604 -1.1.1.75 * rattus norvegicus 0.001 0.0007999999999999999 2 PMID:4303396;PMID:6029609 -1.1.1.76 * corynebacterium glutamicum 277.6 3.55 10 PMID:11169050;PMID:11577733;PMID:19941855;PMID:24025762 -1.1.1.76 * pseudomonas aeruginosa 8.286 1.671 9 PMID:30058099 -1.1.1.76 * rhodococcus erythropolis 8519.0 4394.0 2 PMID:23568047 -1.1.1.76 * serratia sp. t241 1.14 1.14 1 PMID:27713210 -1.1.1.77 * microcyclus eburneus 36.6 36.6 1 * -1.1.1.78 * capra hircus 69.2 69.2 1 PMID:6386056 -1.1.1.78 * escherichia coli 2.26 2.26 1 * -1.1.1.78 * saccharomyces cerevisiae 8.35 8.35 1 PMID:12722185 -1.1.1.79 * acetobacter aceti 1300.0 881.5 2 PMID:32729375 -1.1.1.79 * euglena gracilis 17.1 17.1 1 PMID:3922357 -1.1.1.79 * glycine max 0.45 0.45 1 PMID:3548703 -1.1.1.79 * neurospora crassa 108.1 108.1 1 * -1.1.1.79 * nicotiana tabacum 0.3 0.3 1 PMID:16660267 -1.1.1.79 * paecilomyces sp. 'thermophila' 70.1 47.15 2 PMID:24835102 -1.1.1.79 * populus gelrica 2.03 2.03 1 PMID:16661194 -1.1.1.79 * saccharomyces cerevisiae 61.7 8.845 4 PMID:17173333;PMID:383706;PMID:6993451 -1.1.1.79 * spinacia oleracea 210.6 210.6 1 PMID:3548703 -1.1.1.79 * triticum aestivum 0.45 0.45 1 PMID:3548703 -1.1.1.8 * apis mellifera 340.0 340.0 1 PMID:236444 -1.1.1.8 * aspergillus nidulans 0.028 0.028 1 PMID:11123696 -1.1.1.8 * ceratitis capitata 198.9 198.9 1 PMID:14695 -1.1.1.8 * chlamydomonas reinhardtii 34.0 34.0 1 PMID:2719977 -1.1.1.8 * coturnix japonica 806.0 96.0 7 PMID:4346261 -1.1.1.8 * cynomys ludovicianus 282.0 269.5 2 PMID:22180227 -1.1.1.8 * debaryomyces hansenii 200.0 200.0 1 PMID:1972335 -1.1.1.8 * drosophila melanogaster 179.8 156.0 3 PMID:6768747 -1.1.1.8 * drosophila virilis 71.8 71.8 1 PMID:6774753 -1.1.1.8 * eidolon helvum 120.0 120.0 1 PMID:12689513 -1.1.1.8 * gallus gallus 310.0 310.0 1 PMID:236445 -1.1.1.8 * homo sapiens 250.0 169.1 2 PMID:3943520;PMID:7671141 -1.1.1.8 * jaculus orientalis 55.6 54.6 2 PMID:11952153 -1.1.1.8 * leishmania mexicana 154.0 154.0 1 PMID:10743613 -1.1.1.8 * oryctolagus cuniculus 295.0 162.0 7 PMID:195955;PMID:226146;PMID:4200180;PMID:4778280;PMID:718960 -1.1.1.8 * rattus norvegicus 152.4 152.4 1 PMID:4433563 -1.1.1.8 * saccharomyces cerevisiae 2396.0 104.05 4 PMID:12032156;PMID:1499720;PMID:6808861;PMID:8879163 -1.1.1.8 * spinacia oleracea 37.5 37.5 1 PMID:39510 -1.1.1.8 * trypanosoma brucei 170.0 125.0 2 PMID:2940090;PMID:8920004 -1.1.1.8 * urocitellus richardsonii 2.9 2.537 2 PMID:27521690 -1.1.1.8 * wickerhamiella versatilis 0.00147 0.0011849999999999999 2 PMID:26906228 -1.1.1.81 * bos taurus 104.8 53.735 2 PMID:4146372;PMID:804293 -1.1.1.81 * cucumis sativus 0.1 0.1 1 PMID:8759789 -1.1.1.81 * delftia acidovorans 14.6 14.6 1 PMID:4385077 -1.1.1.81 * hordeum vulgare 0.0834 0.0757 2 PMID:16667032;PMID:16667783 -1.1.1.81 * hyphomicrobium methylovorum gm2 943.0 472.45 2 PMID:8055948;PMID:8759789 -1.1.1.81 * methylobacterium organophilum 1.5 1.5 1 PMID:8759789 -1.1.1.81 * methylorubrum extorquens am1 675.0 338.35 2 PMID:1657886;PMID:8759789 -1.1.1.81 * nicotiana tabacum cv. sr1 13.01 13.01 1 PMID:8316213 -1.1.1.81 * paracoccus denitrificans 0.33 0.135 3 * -1.1.1.81 * spinacia oleracea 260.0 179.0 4 PMID:2039466;PMID:24220768;PMID:3281657;PMID:8759789 -1.1.1.81 * sus scrofa 0.745 0.745 1 PMID:236450 -1.1.1.81 * zea mays 1.06 1.06 1 PMID:16667010 -1.1.1.82 * cicer arietinum 1.35 1.35 1 * -1.1.1.82 * echinochloa crus-galli 211.0 196.0 2 * -1.1.1.82 * lathyrus oleraceus 184.0 184.0 1 * -1.1.1.82 * spinacia oleracea 46.0 46.0 1 * -1.1.1.82 * zea mays 945.0 552.5 2 PMID:16661905;PMID:3341761 -1.1.1.83 * cereibacter sphaeroides 20.6 20.6 1 PMID:6345505 -1.1.1.83 * pseudomonas fluorescens 13.02 13.02 1 PMID:6778506 -1.1.1.84 * pseudomonas fluorescens 12.54 12.54 1 PMID:6778506 -1.1.1.84 * pseudomonas sp. 4.1 4.1 1 PMID:4287371 -1.1.1.85 * acidithiobacillus ferrooxidans 138.2 138.2 1 PMID:8282728 -1.1.1.85 * bacillus subtilis 13.9 13.9 1 PMID:17389690 -1.1.1.85 * heyndrickxia coagulans 10.5 10.5 1 PMID:6087910 -1.1.1.85 * pseudomonas aeruginosa 0.54 0.54 1 PMID:4310224 -1.1.1.85 * saccharomyces cerevisiae 19.3 18.85 2 PMID:3071718;PMID:6993484 -1.1.1.85 * salmonella enterica subsp. enterica serovar typhimurium 54.0 54.0 1 * -1.1.1.85 * sulfolobus sp. 19.4 19.4 2 PMID:7557336 -1.1.1.85 * sulfurisphaera tokodaii 15.9 15.9 1 PMID:9023199 -1.1.1.85 * synthetic construct 39.1 20.63 4 PMID:32968141 -1.1.1.86 * campylobacter jejuni 1.4 0.95 2 PMID:32745463 -1.1.1.86 * corynebacterium glutamicum 0.15 0.15 1 PMID:12948642 -1.1.1.86 * escherichia coli 1.9 1.9 1 PMID:2189496 -1.1.1.86 * hordeum vulgare 3.04 3.04 1 PMID:12231988 -1.1.1.86 * mycobacterium tuberculosis 6.0 3.2 2 PMID:32745463 -1.1.1.86 * neurospora crassa 18.5 18.5 1 * -1.1.1.86 * oryza sativa 1.97 1.685 2 * -1.1.1.86 * salmonella enterica subsp. enterica serovar typhimurium 4.94 3.4250000000000003 2 PMID:4388025;PMID:803501 -1.1.1.86 * spinacia oleracea 5.0 3.79 3 PMID:2590180;PMID:9187358 -1.1.1.87 * saccharomyces cerevisiae 3.8 3.8 1 PMID:4395693 -1.1.1.87 * saccharomycopsis lipolytica 6.304 6.304 1 PMID:6759120 -1.1.1.87 * thermus thermophilus 8579.0 4571.5 2 PMID:12427751 -1.1.1.88 * burkholderia cenocepacia 11.0 6.0 3 PMID:31469273 -1.1.1.88 * delftia acidovorans 11.94 8.405 2 PMID:21810477 -1.1.1.88 * mesocricetus auratus 1.203 1.0625 2 PMID:8415689 -1.1.1.88 * mycobacterium sp. 0.17 0.17 1 * -1.1.1.88 * pseudomonas sp. 'mevalonii' 70.5 18.0 7 PMID:1634543;PMID:21810477;PMID:2681186;PMID:4019479 -1.1.1.9 * aeribacillus pallidus 23.5 23.5 1 * -1.1.1.9 * candida tropicalis 130.0 130.0 1 PMID:10779871 -1.1.1.9 * fusarium oxysporum 250.0 125.34 2 PMID:1482390 -1.1.1.9 * gluconobacter oxydans 564.0 107.75 16 PMID:12723607;PMID:26975753 -1.1.1.9 * klebsiella aerogenes 3.1 3.1 1 PMID:13789254 -1.1.1.9 * meyerozyma caribbica 4.9 2.0 3 PMID:27506274 -1.1.1.9 * meyerozyma guilliermondii 0.567 0.567 1 PMID:12111747 -1.1.1.9 * morganella morganii 0.11 0.11 1 PMID:3886639 -1.1.1.9 * pachysolen tannophilus 29.9 15.399999999999999 2 PMID:16347161 -1.1.1.9 * pichia kudriavzevii 14.66 14.66 1 PMID:32171656 -1.1.1.9 * providencia stuartii 0.22 0.22 1 PMID:3886639 -1.1.1.9 * rhizomucor pusillus 57.8 34.75 2 PMID:25082263 -1.1.1.9 * saccharomyces cerevisiae 2.16 2.16 1 PMID:16977466 -1.1.1.9 * scheffersomyces shehatae 15.95 8.049999999999999 2 PMID:1393828 -1.1.1.9 * scheffersomyces stipitis 13.29 13.29 1 PMID:32171656 -1.1.1.9 * serratia marcescens 0.11 0.11 1 PMID:3886639 -1.1.1.9 * spathaspora passalidarum 2.95 1.745 4 * -1.1.1.9 * torulaspora delbrueckii 10.71 10.71 1 PMID:32171656 -1.1.1.9 * yamadazyma tenuis 2.0 2.0 1 PMID:9103975 -1.1.1.90 * acinetobacter calcoaceticus 238.0 238.0 1 PMID:3291854 -1.1.1.90 * cupriavidus necator 0.22 0.22 1 PMID:12200281 -1.1.1.90 * paecilomyces variotii 0.05 0.026 4 PMID:16085815 -1.1.1.90 * pseudomonas putida 376.0 125.305 4 PMID:12200281;PMID:2202600;PMID:743216 -1.1.1.90 * streptomyces sp. 10.7 10.7 1 PMID:23500723 -1.1.1.90 * thauera sp. 0.106 0.106 1 PMID:7575097 -1.1.1.91 * nocardia asteroides 0.011 0.011 1 * -1.1.1.92 * pseudomonas putida 7.7 5.15 2 PMID:4385076 -1.1.1.93 * cereibacter sphaeroides 1.88 1.88 1 PMID:6345505 -1.1.1.93 * pseudomonas putida 0.71 0.3841 2 PMID:2184888;PMID:4297261 -1.1.1.94 * aspergillus oryzae 0.028 0.013000000000000001 4 PMID:15073319 -1.1.1.94 * escherichia coli 4800.0 4800.0 1 PMID:4389388 -1.1.1.94 * escherichia coli k-12 70.0 70.0 1 PMID:355254 -1.1.1.95 * arabidopsis thaliana 10.95 5.545 2 PMID:9867856 -1.1.1.95 * bacillus subtilis 15.6 15.6 1 PMID:168067 -1.1.1.95 * entamoeba histolytica 0.495 0.495 1 PMID:25294608 -1.1.1.95 * escherichia coli 9.7 9.2 2 PMID:8550422 -1.1.1.95 * gallus gallus 71.0 71.0 1 PMID:564904 -1.1.1.95 * glycine max 21.3 21.3 1 PMID:16662883 -1.1.1.95 * lathyrus oleraceus 11.8 11.8 1 PMID:236449 -1.1.1.95 * marchantia polymorpha 5.65 5.65 1 PMID:30061906 -1.1.1.95 * oryctolagus cuniculus 81.3 81.3 1 PMID:3800969 -1.1.1.97 * penicillium urticae 522.0 522.0 1 PMID:3516352 -1.1.1.97 * pseudomonas putida 0.78 0.675 4 PMID:6989805 -1.1.2.11 * halomonas sp. 0.86 0.74 3 PMID:15304701 -1.1.2.2 * komagataeibacter xylinus 213.0 213.0 1 * -1.1.2.3 * ogataea angusta 11.0 3.0 7 PMID:18522323;PMID:21315405;PMID:24223505;PMID:26452947 -1.1.2.3 * rhizopus arrhizus 0.72 0.415 3 PMID:4334855 -1.1.2.3 * rhodovulum steppense 4.75 4.75 1 * -1.1.2.3 * saccharomyces cerevisiae 3.2 0.66 3 PMID:19451036 -1.1.2.3 * wickerhamomyces anomalus 895.0 895.0 1 PMID:697031 -1.1.2.4 * megasphaera elsdenii 20.3 20.3 1 PMID:497162 -1.1.2.4 * saccharomyces cerevisiae 1670.0 4.545 6 PMID:13729965;PMID:13950255 -1.1.2.4 * stutzerimonas stutzeri 2.7 2.7 1 PMID:17805529 -1.1.2.6 * pseudomonas sp. 19.8 19.8 1 * -1.1.2.6 * sphingopyxis sp. 18.0 18.0 1 PMID:16804170 -1.1.2.7 * hyphomicrobium denitrificans 18.0 13.0 3 PMID:16533029 -1.1.2.7 * methylomicrobium sp. hg-1 4210.0 4210.0 1 * -1.1.2.7 * methylophaga aminisulfidivorans 21.03 9.705 8 PMID:21656818 -1.1.2.7 * methylorubrum extorquens 5.4 5.4 1 PMID:16139516 -1.1.2.7 * methylosinus sp. 6.12 6.12 1 PMID:9726124 -1.1.2.8 * gluconobacter sp. chm43 0.55 0.0875 28 PMID:33686415 -1.1.2.8 * pseudomonas aeruginosa 40.0 40.0 1 PMID:8382472 -1.1.2.9 * thauera butanivorans 4.8 2.465 2 PMID:11238982 -1.1.3.10 * aspergillus nidulans 1.16 1.16 1 PMID:21968652 -1.1.3.10 * aspergillus oryzae 0.58 0.58 1 PMID:21968652 -1.1.3.10 * auricularia polytricha 0.19 0.19 1 * -1.1.3.10 * basidiomycota 33.3 17.055 2 * -1.1.3.10 * gloeophyllum sepiarium 0.22 0.22 1 * -1.1.3.10 * irpex lacteus 8.64 0.31 3 * -1.1.3.10 * phanerodontia chrysosporium 31.0 23.25 2 PMID:9210340 -1.1.3.10 * phlebiopsis gigantea 10.4 8.15 3 PMID:15660220;PMID:16535364;PMID:8319689 -1.1.3.10 * polyporus obtusus 12.8 8.55 6 PMID:1423351;PMID:236434;PMID:5725162 -1.1.3.10 * trametes cinnabarinus 0.011 0.011 1 * -1.1.3.10 * trametes ochracea 12.0 12.0 1 PMID:11472941 -1.1.3.10 * trametes sp. 6.4 6.4 1 PMID:29536215 -1.1.3.10 * trametes versicolor 30.9 15.764999999999999 2 * -1.1.3.10 * tricholoma matsutake 25.8 25.8 1 PMID:14730138 -1.1.3.12 * brucella anthropi 4.1e-06 4.1e-06 1 * -1.1.3.12 * enterobacter cloacae 9.4e-06 9.4e-06 1 * -1.1.3.12 * mesorhizobium loti 19.4 19.4 1 PMID:15135526 -1.1.3.12 * microbacterium luteolum 21.1 10.75 2 PMID:12092811;PMID:19111641 -1.1.3.13 * [candida] boidinii 10.94 10.94 1 * -1.1.3.13 * [candida] methanosorbosa 4.11 4.11 1 PMID:9142745 -1.1.3.13 * [candida] sp. 2.8 2.8 1 * -1.1.3.13 * arthrobacter globiformis 0.02 0.010075 2 PMID:30338899 -1.1.3.13 * aspergillus ochraceus 3.64 3.59 3 PMID:17113587;PMID:17726298 -1.1.3.13 * aspergillus terreus 305.0 63.0 11 PMID:19060312 -1.1.3.13 * basidiomycota 9.5 9.5 1 PMID:236460 -1.1.3.13 * fungi 1.86 1.7400000000000002 2 PMID:12018252 -1.1.3.13 * gloeophyllum trabeum 12.0 12.0 1 PMID:17660304 -1.1.3.13 * komagataella pastoris 12.94 11.9 3 * -1.1.3.13 * ochrobactrum sp. 4.02 2.03035 2 * -1.1.3.13 * ogataea angusta 23.2 7.43 10 PMID:16545060;PMID:2280715 -1.1.3.13 * ogataea thermomethanolica (nom. inval.) 15.34 15.34 1 PMID:29738827 -1.1.3.13 * paecilomyces variotii 1.42 1.42 1 PMID:17985128 -1.1.3.13 * phanerodontia chrysosporium 17.3 16.9 2 * -1.1.3.13 * phlebiopsis gigantea 8.7 8.7 1 * -1.1.3.13 * pichia sp. 6.6 6.6 1 PMID:7030206 -1.1.3.13 * poria contigua 20.7 20.7 1 PMID:118005 -1.1.3.13 * thermoascus aurantiacus 9.42 5.545 2 PMID:16233800 -1.1.3.15 * aerococcus viridans 210.0 210.0 1 PMID:8589073 -1.1.3.15 * amaranthus retroflexus 1.33 0.62 3 * -1.1.3.15 * gallus gallus 2.08 2.08 1 PMID:2194838 -1.1.3.15 * geotrichum candidum 60.7 60.7 1 PMID:8766696 -1.1.3.15 * pediococcus sp. 72.0 41.0 3 PMID:20136130;PMID:20449373;PMID:20664851 -1.1.3.15 * rattus sp. 25.43 1.04 8 PMID:1148170;PMID:1261544;PMID:3061453;PMID:4705431;PMID:5686300;PMID:7023357;PMID:8706682 -1.1.3.15 * streptococcus iniae 45.76 36.915 2 PMID:19270123 -1.1.3.15 * zea mays 1546.0 0.6000000000000001 4 PMID:12964860 -1.1.3.16 * calliphora vicina 11.2 11.2 1 * -1.1.3.16 * manduca sexta 0.0335 0.0028 3 * -1.1.3.16 * spodoptera littoralis 0.321 0.321 1 * -1.1.3.17 * arthrobacter globiformis 12.8 11.55 4 PMID:30338899;PMID:599154 -1.1.3.17 * cylindrocarpon didymum 7.57 7.57 1 * -1.1.3.17 * fusarium oxysporum 32.1 32.1 1 PMID:23221722 -1.1.3.18 * bacteria 3.8 3.8 1 * -1.1.3.18 * brevundimonas vesicularis 0.7 0.7 1 * -1.1.3.18 * pseudomonas sp. 22.73 1.5 3 * -1.1.3.18 * sphingomonas sp. 0.0018 0.0018 1 PMID:17594087 -1.1.3.2 * aerococcus viridans 272.0 210.0 3 PMID:11916135;PMID:2818595;PMID:8589073 -1.1.3.20 * [candida] cloacae 0.08 0.08 1 PMID:10660617 -1.1.3.20 * candida tropicalis 30.0 0.192 7 PMID:1546949 -1.1.3.20 * starmerella bombicola 0.144 0.093 2 PMID:2227354 -1.1.3.20 * tanacetum vulgare 2.6 2.6 1 * -1.1.3.20 * uncultured marine group ii/iii euryarchaeote km3_72_h01 0.23 0.23 1 PMID:34709726 -1.1.3.20 * yarrowia lipolytica 0.07 0.044750000000000005 2 * -1.1.3.21 * aerococcus viridans 433.2 433.2 1 PMID:11759680 -1.1.3.21 * enterococcus faecium 85.0 62.0 3 PMID:3771536;PMID:429313;PMID:5788698 -1.1.3.21 * mycoplasma mycoides 0.025 0.025 1 PMID:2283028 -1.1.3.23 * unidentified soil bacterium 2.18 2.18 1 PMID:4987737 -1.1.3.28 * stenotrophomonas maltophilia 15.3 15.3 1 * -1.1.3.29 * pseudomonas sp. 70.4 70.4 1 * -1.1.3.30 * brevundimonas vesicularis 0.7 0.7 1 * -1.1.3.30 * pseudomonas sp. 1.68 1.68 1 PMID:3513704 -1.1.3.30 * sphingomonas sp. 0.0018 0.0018 1 PMID:17594087 -1.1.3.30 * sphingopyxis sp. 18.0 18.0 1 PMID:16804170 -1.1.3.37 * candida albicans 18.8 18.8 1 PMID:8841374 -1.1.3.38 * methylovorus sp. mp688 3.3 3.3 1 PMID:32503910 -1.1.3.38 * penicillium simplicissimum 2.13 2.13 1 PMID:1396672 -1.1.3.38 * pseudomonas sp. 11/12a 2.0 2.0 1 PMID:32503910 -1.1.3.39 * elizabethkingia meningoseptica 91.8 91.8 1 PMID:16535726 -1.1.3.4 * aspergillus niger 216.0 100.0 13 PMID:1213991;PMID:12182830;PMID:16788719;PMID:19784554;PMID:23682574;PMID:24283586 -1.1.3.4 * penicillium amagasakiense 3.63 3.63 1 PMID:5577148 -1.1.3.4 * penicillium chrysogenum 59.37 32.449999999999996 2 * -1.1.3.4 * penicillium sp. 240.5 240.5 1 PMID:17084642 -1.1.3.4 * penicillium sp. mx3343 149.05 149.05 1 PMID:33329498 -1.1.3.4 * phanerodontia chrysosporium 15.1 15.1 1 PMID:3226296;PMID:3957868 -1.1.3.4 * streptomyces coelicolor 17.3 17.3 1 * -1.1.3.4 * talaromyces funiculosus 914.0 499.7 2 PMID:23996117 -1.1.3.4 * talaromyces variabilis 144.0 72.165 2 * -1.1.3.40 * cornu aspersum 0.984 0.49885 2 PMID:3519307 -1.1.3.41 * streptomyces coelicolor 17.3 17.3 1 * -1.1.3.42 * alternaria solani 1.69 0.01082 4 PMID:18256508;PMID:9659400 -1.1.3.43 * streptomyces fradiae 4.2 4.2 1 PMID:21689223 -1.1.3.44 * streptomyces fradiae 6.4 6.4 1 PMID:21689223 -1.1.3.44 * streptomyces lividus 3.5 3.5 1 PMID:21689223 -1.1.3.46 * amycolatopsis orientalis 310.0 310.0 1 PMID:25011099 -1.1.3.46 * streptomyces coelicolor 1822.0 1822.0 1 PMID:25011099 -1.1.3.47 * methylovorus sp. mp688 3.3 3.3 1 PMID:32503910 -1.1.3.47 * pseudomonas nitroreducens 0.2 0.2 1 PMID:32503910 -1.1.3.47 * pseudomonas sp. 11/12a 2.0 2.0 1 PMID:32503910 -1.1.3.5 * chondrus crispus 120.0 42.5 4 PMID:11427234;PMID:4708670;PMID:9108257;PMID:9111074 -1.1.3.5 * mazzaella flaccida 0.3 0.3 1 PMID:13278350 -1.1.3.50 * microbacterium sp. 5-2b 19.9 19.9 1 PMID:34583991 -1.1.3.6 * bacillus sp. (in: firmicutes) 8.0 7.8 2 * -1.1.3.6 * bacillus subtilis 1.39 1.39 1 PMID:26453032 -1.1.3.6 * bordetella sp. 20.81 20.81 1 * -1.1.3.6 * brevibacterium sp. 17.5 14.0 4 * -1.1.3.6 * brevibacterium sterolicum 55.2 36.1 2 PMID:12399041 -1.1.3.6 * burkholderia cepacia 16.9 16.9 1 PMID:11693912 -1.1.3.6 * castellaniella sp. 15.0 15.0 1 PMID:31750957 -1.1.3.6 * chromobacterium sp. ds-1 13.9 13.9 1 PMID:18512056 -1.1.3.6 * chryseobacterium gleum 15.5 15.5 1 PMID:24885249 -1.1.3.6 * enterococcus hirae 124.87 124.87 1 PMID:26369334 -1.1.3.6 * gamma proteobacterium y-134 39.6 27.0 2 PMID:16233402;PMID:16233518 -1.1.3.6 * mycolicibacterium neoaurum 17.2 0.24 21 PMID:23164577 -1.1.3.6 * nocardia rhodochrous 0.045 0.045 1 PMID:6953966 -1.1.3.6 * nocardia sp. 0.6 0.6 1 PMID:3479986 -1.1.3.6 * pimelobacter simplex 3.65 3.035 2 * -1.1.3.6 * pseudomonas sp. 27.9 21.549999999999997 2 PMID:9572974 -1.1.3.6 * rhodococcus sp. (in: high g+c gram-positive bacteria) 35.64 35.64 1 PMID:26276474 -1.1.3.6 * streptomyces aegyptia 16.08 16.08 1 PMID:28356065 -1.1.3.6 * streptomyces natalensis 12.15 12.15 1 PMID:17379143 -1.1.3.6 * streptomyces parvus 20.0 20.0 1 PMID:21909628 -1.1.3.6 * streptomyces sp. 67.7 21.8 3 PMID:23700127;PMID:9153088 -1.1.3.6 * streptomyces violascens 19.7 19.7 1 PMID:956143 -1.1.3.7 * bjerkandera adusta 210.0 210.0 1 * -1.1.3.7 * lentinus sajor-caju 30.7 30.7 1 PMID:3060110 -1.1.3.7 * methylovorus sp. mp688 3.3 3.3 1 PMID:32503910 -1.1.3.7 * phanerodontia chrysosporium 1.64 1.64 1 * -1.1.3.7 * pleurotus eryngii 96.0 79.5 3 PMID:1425667;PMID:16039872;PMID:26162870 -1.1.3.7 * pleurotus ostreatus 63.6 41.5 5 PMID:20857231 -1.1.3.7 * pleurotus pulmonarius 121.1 60.879999999999995 2 PMID:10606774;PMID:15858792 -1.1.3.7 * pleurotus sapidus 88.1 88.1 1 PMID:27138199 -1.1.3.7 * pseudomonas nitroreducens 0.2 0.2 1 PMID:32503910 -1.1.3.7 * pseudomonas sp. 11/12a 2.0 2.0 1 PMID:32503910 -1.1.3.7 * sphingobacterium sp. 21.75 21.75 1 * -1.1.3.8 * arabidopsis thaliana 4.7 4.7 1 PMID:30112455 -1.1.3.8 * capra hircus 2.05 2.05 1 PMID:440104;PMID:822334 -1.1.3.8 * gallus gallus 3.43 3.43 1 PMID:7138847 -1.1.3.8 * rattus norvegicus 100.0 0.54 5 PMID:440104;PMID:822334;PMID:8459881;PMID:9211253;PMID:9685663 -1.1.3.9 * fusarium fujikuroi 3.32 3.3099999999999996 2 * -1.1.3.9 * fusarium graminearum 132.0 132.0 1 PMID:24493559 -1.1.3.9 * fusarium oxysporum 65.4 63.2 3 PMID:24967652 -1.1.3.9 * fusarium sambucinum 226.0 192.5 2 PMID:25543085 -1.1.3.9 * hypomyces rosellus 2038.0 487.0 8 PMID:12058898;PMID:2542244;PMID:3813549;PMID:4441089;PMID:6890617;PMID:7192504;PMID:7929198 -1.1.3.9 * paenibacillus sp. aiu 311 0.807 0.807 1 PMID:17884657 -1.1.5.12 * escherichia coli 230.0 230.0 1 PMID:369600 -1.1.5.12 * pseudomonas putida kt2440 44.5 44.5 1 PMID:28847921 -1.1.5.13 * arabidopsis thaliana 520.0 520.0 1 PMID:26203119 -1.1.5.14 * gluconobacter oxydans 172.0 172.0 1 PMID:7462161 -1.1.5.2 * acinetobacter calcoaceticus 7400.0 2815.0 12 PMID:10518528;PMID:15571780;PMID:15715904;PMID:2549865;PMID:3800975;PMID:8951033 -1.1.5.2 * arthrobacter globiformis 88.1 44.3 2 PMID:25580683 -1.1.5.2 * erwinia sp. 12.0 12.0 2 PMID:12765523 -1.1.5.2 * escherichia coli 211.0 180.5 2 PMID:11604400;PMID:8509415 -1.1.5.2 * gluconacetobacter diazotrophicus 130.0 126.0 3 PMID:25576305 -1.1.5.2 * gluconobacter oxydans 616.0 150.0 3 PMID:22790543;PMID:2547757 -1.1.5.2 * pantoea ananatis 0.0197 0.011075 2 PMID:21306430 -1.1.5.2 * pseudomonas aeruginosa 0.058 0.0475 2 PMID:18996187 -1.1.5.2 * pseudomonas fluorescens 386.0 193.004 2 PMID:18996187 -1.1.5.2 * pyrobaculum aerophilum 0.77 0.77 1 PMID:20692227 -1.1.5.3 * sus scrofa 2.9 2.025 2 PMID:5775687;PMID:6796038 -1.1.5.4 * mycobacterium sp. 310.0 310.0 1 PMID:629992 -1.1.5.4 * mycolicibacterium phlei 52.0 52.0 1 * -1.1.5.4 * pseudomonas putida 9.3 9.3 1 * -1.1.5.4 * pseudomonas taetrolens 9.3 9.3 1 PMID:33166455 -1.1.5.5 * acetobacter pasteurianus 205.0 205.0 1 PMID:16133326 -1.1.5.5 * acetobacter sp. 293.0 293.0 1 PMID:16636451 -1.1.5.5 * frateuria aurantia 3.0 3.0 1 PMID:23760531 -1.1.5.5 * gluconacetobacter diazotrophicus 258.0 258.0 1 PMID:18321602 -1.1.5.5 * gluconobacter sp. 32.2 28.6 2 PMID:10464483 -1.1.5.5 * komagataeibacter europaeus 179.0 179.0 1 PMID:16133326 -1.1.5.5 * komagataeibacter intermedius 192.0 192.0 1 PMID:16133326 -1.1.5.5 * pseudomonas aeruginosa 8.5 4.5 17 PMID:20082374 -1.1.5.7 * gluconobacter frateurii 44.3 44.3 1 PMID:11826975 -1.1.5.8 * acinetobacter calcoaceticus 21.0 21.0 1 PMID:14586098 -1.1.5.9 * aspergillus sp. 795.0 795.0 1 PMID:22222911 -1.1.5.9 * burkholderia cepacia 950.0 139.0 7 PMID:18581061 -1.1.5.9 * colletotrichum gloeosporioides 878.0 838.0 4 PMID:21903757;PMID:22151971;PMID:22222911 -1.1.5.9 * komagataella pastoris 836.0 836.0 1 PMID:22222911 -1.1.7.1 * thauera aromatica 4.0 4.0 1 PMID:18393440 -1.1.9.1 * comamonas testosteroni 20.5 20.5 1 PMID:7601151 -1.1.9.1 * pseudomonas putida 14.0 14.0 1 PMID:7730276 -1.1.98.2 * gordonia amarae 0.02 0.02 1 PMID:8997717 -1.1.98.2 * mycobacterium avium 0.313 0.313 1 PMID:8997717 -1.1.98.2 * mycobacterium gordonae 0.156 0.156 1 PMID:8997717 -1.1.98.2 * mycobacterium kansasii 0.025 0.025 1 PMID:8997717 -1.1.98.2 * mycobacterium leprae 0.008 0.008 1 PMID:8997717 -1.1.98.2 * mycobacterium scrofulaceum 0.152 0.152 1 PMID:8997717 -1.1.98.2 * mycobacterium tuberculosis 0.117 0.0655 2 PMID:8997717 -1.1.98.2 * mycolicibacterium fortuitum 0.083 0.083 1 PMID:8997717 -1.1.98.2 * mycolicibacterium smegmatis 50.9 25.659 2 PMID:8631674;PMID:8997717 -1.1.98.2 * nocardia asteroides 0.088 0.088 1 PMID:8997717 -1.1.98.2 * nocardia brasiliensis 0.093 0.093 1 PMID:8997717 -1.1.98.2 * nocardia otitidiscaviarum 0.154 0.154 1 PMID:8997717 -1.1.98.2 * nocardia tartaricans 0.076 0.076 1 PMID:8997717 -1.1.98.4 * archaeoglobus fulgidus 9.3 4.755000000000001 2 PMID:10971593 -1.1.98.4 * methanosarcina mazei gö1 173.0 102.0 4 * -1.1.98.5 * methanoculleus thermophilus 176.0 143.0 2 * -1.1.98.6 * escherichia coli 260.0 260.0 1 PMID:1460049 -1.1.98.6 * tequatrovirus t4 1155.0 652.5 4 PMID:10748029 -1.1.99.1 * halomonas elongata 1.8 1.8 1 PMID:12676692 -1.1.99.1 * pseudomonas aeruginosa 67.0 67.0 1 PMID:7765090 -1.1.99.1 * rattus norvegicus 6.3 0.047 3 PMID:12951056;PMID:6996732 -1.1.99.12 * escherichia coli 10.3 10.3 1 PMID:17404730 -1.1.99.12 * gluconobacter oxydans 6.73 3.3699500000000002 2 PMID:5354025 -1.1.99.13 * agaricus bisporus 149.0 149.0 1 * -1.1.99.13 * flavobacterium saccharophilum 2.94 2.94 1 PMID:3818559 -1.1.99.13 * sphingobacterium faecium 7.54 1.48 4 PMID:24585380;PMID:28044272 -1.1.99.13 * stenotrophomonas maltophilia 0.244 0.244 1 * -1.1.99.14 * arabidopsis thaliana 0.035 0.025 2 PMID:17595195 -1.1.99.14 * dunaliella salina 0.042 0.042 1 PMID:24227444 -1.1.99.14 * escherichia coli 3.1 0.15 3 PMID:4557653 -1.1.99.14 * thalassiosira pseudonana 0.009 0.009 1 PMID:4217144 -1.1.99.14 * trichoderma harzianum 0.727 0.364325 2 * -1.1.99.18 * agroathelia rolfsii 66.0 44.95 4 PMID:11282631;PMID:18353295 -1.1.99.18 * amesia atrobrunnea 11.5 9.3 2 PMID:21216904 -1.1.99.18 * cerrena unicolor 14.7 14.4 3 PMID:26003328;PMID:29418014 -1.1.99.18 * coniophora puteana (schum ex fr) karsten 2.18 2.18 1 PMID:8434937 -1.1.99.18 * dichomera saubinetii 13.2 12.75 2 PMID:21216904 -1.1.99.18 * fungi 7.78 7.78 1 PMID:14714477 -1.1.99.18 * gelatoporia subvermispora 20.3 20.3 1 PMID:19270118 -1.1.99.18 * hypoxylon haematostroma 9.0 8.2 2 PMID:21216904 -1.1.99.18 * mycothermus thermophilus 4409.0 4409.0 1 PMID:9461557 -1.1.99.18 * neurospora crassa 10.3 6.8149999999999995 6 PMID:21216904 -1.1.99.18 * phanerochaete sordida 33.0 33.0 1 * -1.1.99.18 * phanerodontia chrysosporium 39.0 10.9 6 PMID:10328816;PMID:20120044;PMID:33407462;PMID:7144569;PMID:8434950 -1.1.99.18 * schizophyllum commune 11.4 11.4 1 PMID:9578598 -1.1.99.18 * stachybotrys bisbyi 2.7 2.45 2 PMID:21216904 -1.1.99.18 * termitomyces clypeatus 16.76 16.76 1 * -1.1.99.18 * termitomyces sp. oe 147 324.0 324.0 1 PMID:33063604 -1.1.99.18 * thermothelomyces fergusii 17.8 13.350000000000001 2 PMID:21216904 -1.1.99.18 * thermothelomyces heterothallicus 13.4 5.3 3 PMID:10328816 -1.1.99.18 * thermothelomyces myriococcoides 10.7 6.565 8 PMID:18353295;PMID:18374601;PMID:23199740;PMID:23617537 -1.1.99.18 * thermothielavioides terrestris 0.85 0.85 1 PMID:22484439 -1.1.99.18 * trametes cinnabarina 13.6 13.6 1 * -1.1.99.18 * trametes hirsuta 16.3 1.79 5 PMID:16861797 -1.1.99.18 * trametes pubescens 62.0 62.0 1 PMID:14666391 -1.1.99.18 * trametes sanguinea 1770.0 724.15 4 PMID:24315647 -1.1.99.18 * trametes villosa 69.0 69.0 1 PMID:14666391 -1.1.99.2 * homo sapiens 0.021 0.021 1 PMID:8241290 -1.1.99.2 * rattus norvegicus 0.0046 0.0046 1 PMID:8241290 -1.1.99.20 * flavobacterium sp. 2.68 0.032 10 PMID:3800554;PMID:6999995 -1.1.99.20 * pseudomonas sp. 1.2 0.092 6 PMID:3800554;PMID:6999995 -1.1.99.21 * gluconobacter oxydans 3570.0 433.0 3 PMID:18502922;PMID:27633501 -1.1.99.22 * gluconobacter oxydans 52.0 52.0 1 * -1.1.99.24 * mus musculus 0.0013 0.0013 1 PMID:16616524 -1.1.99.24 * rattus norvegicus 0.0513 0.0513 1 PMID:3182820 -1.1.99.26 * pseudomonas sp. 0.27 0.27 1 * -1.1.99.28 * zymomonas mobilis 245.0 70.195 6 PMID:18576080;PMID:19239494;PMID:3745122 -1.1.99.29 * agaricus bisporus 16.4 16.4 1 PMID:9042751 -1.1.99.29 * chlorophyllum rhacodes 67.0 67.0 1 PMID:11511865 -1.1.99.29 * macropsalliota meleagris 45.4 33.5 45 PMID:22080342 -1.1.99.3 * campylobacter jejuni 0.0333 0.023700000000000002 2 PMID:18284594 -1.1.99.3 * gluconobacter frateurii 150.0 150.0 1 * -1.1.99.3 * gluconobacter oxydans 237.0 193.0 2 PMID:17720837 -1.1.99.3 * klebsiella pneumoniae 513.0 513.0 1 PMID:6815420 -1.1.99.3 * pseudomonas aeruginosa 561.5 561.5 1 PMID:109426 -1.1.99.3 * pseudomonas fluorescens 470.0 470.0 1 PMID:6815420 -1.1.99.3 * serratia marcescens 502.0 502.0 1 * -1.1.99.30 * proteus mirabilis 600.0 600.0 1 * -1.1.99.30 * proteus vulgaris 1800.0 1000.0 3 PMID:8026480 -1.1.99.31 * pseudomonas aeruginosa 20.5 11.59 2 * -1.1.99.32 * gluconobacter oxydans 0.897 0.897 1 * -1.1.99.35 * acinetobacter calcoaceticus 5811.0 2977.0 3 PMID:10771051 -1.1.99.36 * amycolatopsis methanolica 3.1 0.0115 6 PMID:8385013 -1.1.99.37 * bacillus methanolicus 0.413 0.413 1 PMID:12351635 -1.1.99.37 * mycobacterium sp. 0.48 0.37 3 PMID:19875438 -1.1.99.4 * gluconobacter oxydans 1.247 1.247 1 * -1.1.99.42 * mesorhizobium loti 11.9 11.9 1 PMID:18216065 -1.1.99.6 * candidatus caldarchaeum subterraneum 3.18 3.18 1 PMID:29691195 -1.1.99.6 * oryctolagus cuniculus 7.4 7.4 1 PMID:236454 -1.1.99.6 * proteus vulgaris 1800.0 1035.0 2 PMID:8026480 -1.1.99.6 * thermoproteus tenax 0.85 0.85 1 PMID:30206766 -1.1.99.7 * veillonella parvula 368.0 265.0 3 PMID:4289051;PMID:4333516;PMID:4352258;PMID:6755174 -1.1.99.9 * arthrobacter sp. 11.9 11.9 1 PMID:3533935 -1.10.3.1 * anethum foeniculum 21380.0 11225.0 2 PMID:33359609 -1.10.3.1 * camellia sinensis 7.3 5.0 4 * -1.10.3.1 * coffea arabica 0.019 0.006 5 PMID:16376392 -1.10.3.1 * coffea brevipes 0.005 0.0026 4 PMID:16376392 -1.10.3.1 * coffea canephora 0.026 0.008 5 PMID:16376392 -1.10.3.1 * coffea eugenioides 0.0124 0.0045 5 PMID:16376392 -1.10.3.1 * coffea guarini 0.09 0.0295 6 PMID:16376392 -1.10.3.1 * coffea kapakata 0.023 0.008 5 PMID:16376392 -1.10.3.1 * coffea liberica 0.011 0.0063 5 PMID:16376392 -1.10.3.1 * coffea liberica var. dewevrei 0.051 0.007 9 PMID:16376392 -1.10.3.1 * coffea racemosa 0.051 0.0265 4 PMID:16376392 -1.10.3.1 * coffea salvatrix 0.004 0.002 3 PMID:16376392 -1.10.3.1 * coffea stenophylla 0.02 0.0052499999999999995 6 PMID:16376392 -1.10.3.1 * eriobotrya japonica 91.5 55.1 2 PMID:16406214 -1.10.3.1 * ferula sp. 41.6 27.375 2 * -1.10.3.1 * fragaria x ananassa 788.3 406.2 2 * -1.10.3.1 * ipomoea batatas 1574.0 1574.0 1 PMID:17651437 -1.10.3.1 * lablab purpureus 29300.0 29300.0 1 PMID:17651437 -1.10.3.1 * lonicera japonica 4.458 2.3015 2 PMID:23265514 -1.10.3.1 * malus domestica 227700.0 227700.0 1 * -1.10.3.1 * mycelia sterilia 10.0 7.199999999999999 4 * -1.10.3.1 * ocimum basilicum 59.46 59.46 1 PMID:16366719 -1.10.3.1 * physalis peruviana 204.69 204.69 1 PMID:26616939 -1.10.3.1 * pouteria sapota 241.5 8.76 3 PMID:21087780 -1.10.3.1 * raphanus sativus 9.8 9.8 1 * -1.10.3.1 * streptomyces cyaneofuscatus 47.6 27.3 2 PMID:29133199 -1.10.3.1 * trichoderma reesei 18.18 18.18 1 PMID:16939623 -1.10.3.1 * urtica dioica 42.57 42.57 1 PMID:16119202 -1.10.3.1 * vitis vinifera 66.0 66.0 1 PMID:7948897 -1.10.3.11 * antonospora locustae 2.2 1.2000000000000002 2 PMID:20169184 -1.10.3.11 * trachipleistophora hominis 1.6 0.8500000000000001 2 PMID:20169184 -1.10.3.15 * streptomyces griseus 0.0658 0.03290175 2 PMID:16282322 -1.10.3.2 * agaricus bisporus 156.0 156.0 1 PMID:19739645 -1.10.3.2 * agaricus sinodeliciosus 1610.0 1610.0 1 PMID:32282952 -1.10.3.2 * agroathelia rolfsii 14.7 14.7 1 * -1.10.3.2 * agrobacterium sp. s5-1 185.4 185.4 1 PMID:26010258 -1.10.3.2 * aquisalibacillus elongatus 498.9 498.9 1 PMID:28161622 -1.10.3.2 * aspergillus nidulans 165.8 165.8 1 PMID:7050088 -1.10.3.2 * bacillus licheniformis 83.47 48.32 2 PMID:34629297 -1.10.3.2 * bacillus sp. (in: firmicutes) 952.0 13.0 5 PMID:20855194;PMID:27059481;PMID:34524901 -1.10.3.2 * bacillus subtilis 228.2 19.3 3 PMID:17957391;PMID:32799230 -1.10.3.2 * basidiomycota 52.0 52.0 1 * -1.10.3.2 * botrytis cinerea 5778.0 2889.83 2 * -1.10.3.2 * carica papaya 41.3 41.3 1 PMID:25192855 -1.10.3.2 * cerrena sp. 1.95 1.95 1 PMID:25356987 -1.10.3.2 * cerrena sp. wr1 144.3 144.3 1 PMID:23081836 -1.10.3.2 * cerrena unicolor 206.0 206.0 1 PMID:15983808 -1.10.3.2 * coniothyrium sp. 30.0 30.0 1 * -1.10.3.2 * coprinopsis cinerea 3138.0 3138.0 1 PMID:30248451 -1.10.3.2 * coriolopsis gallica 313.0 313.0 1 PMID:21145724 -1.10.3.2 * coriolopsis trogii 148.0 23.5 9 PMID:25876603 -1.10.3.2 * cyathus bulleri 4022.0 4000.0 3 PMID:15941663;PMID:16261367;PMID:18083129 -1.10.3.2 * didymosphaeria variabile 18.4 9.625 2 PMID:20933400 -1.10.3.2 * escherichia coli 29.0 2.265 10 PMID:114662690;PMID:17804014;PMID:22564733 -1.10.3.2 * fusarium solani 358.7 181.945 2 PMID:20716485 -1.10.3.2 * ganoderma fornicatum 59.27 59.27 1 * -1.10.3.2 * ganoderma sp. 2.4 2.4 1 * -1.10.3.2 * haloferax volcanii 25.0 25.0 1 PMID:22752793 -1.10.3.2 * kitasatospora aureofaciens 21.6 21.6 1 * -1.10.3.2 * lentinula edodes 305.0 305.0 1 PMID:12949171 -1.10.3.2 * lentinus tigrinus 317.0 159.355 2 PMID:17013550 -1.10.3.2 * leptographium qinlingense (nom. inval.) 195.0 195.0 1 PMID:24214681 -1.10.3.2 * leucaena leucocephala 58.5 58.5 1 * -1.10.3.2 * loweporus lividus 1.41 0.714 2 PMID:18607547 -1.10.3.2 * loweporus lividus mtcc-1178 1.41 1.41 1 * -1.10.3.2 * manduca sexta 10.06 4.1 6 PMID:19576986 -1.10.3.2 * mangifera indica 44.5 44.5 1 * -1.10.3.2 * marinomonas mediterranea 1.34 1.34 1 PMID:27050199 -1.10.3.2 * melanocarpus albomyces 1070.0 275.0 6 PMID:15347764;PMID:19780817 -1.10.3.2 * mycothermus thermophilus 139.4 139.4 1 * -1.10.3.2 * myrioconium sp. 80.0 80.0 1 PMID:17955194 -1.10.3.2 * panus rudis 460.0 460.0 1 * -1.10.3.2 * penicillium cyclopium 600.0 600.0 1 * -1.10.3.2 * penicillium digitatum 576.0 576.0 1 * -1.10.3.2 * perenniporia fraxinea 93.3 93.3 1 PMID:18467859 -1.10.3.2 * phlebia radiata 2.5 2.5 1 PMID:19352024 -1.10.3.2 * phoma sp. 6322.0 3164.55 2 PMID:19455326 -1.10.3.2 * pistacia terebinthus subsp. palaestina 5778.0 5778.0 1 * -1.10.3.2 * pleurotus cornucopiae 17.3 17.3 1 PMID:19807674 -1.10.3.2 * pleurotus ostreatus 2000.0 158.5 10 PMID:19916914;PMID:22806800 -1.10.3.2 * pleurotus pulmonarius 19750.0 19750.0 1 PMID:12872309 -1.10.3.2 * pseudomonas putida 4.57 0.31699999999999995 4 * -1.10.3.2 * pyricularia grisea 225.9 225.9 1 PMID:14568157 -1.10.3.2 * schinus molle 1200.0 1200.0 1 * -1.10.3.2 * shigella dysenteriae 24.4 24.4 1 * -1.10.3.2 * shiraia sp. super-h168 417.7 417.7 1 * -1.10.3.2 * sinorhizobium meliloti 0.402 0.402 1 * -1.10.3.2 * sphingobacterium sp. ksn-11 377.2 377.2 1 PMID:32601857 -1.10.3.2 * steccherinum ochraceum 22.3 20.5 3 PMID:19120652 -1.10.3.2 * streptomyces coelicolor 8.0 8.0 1 PMID:18437373 -1.10.3.2 * talaromyces aculeatus 500.0 500.0 1 * -1.10.3.2 * thermochaetoides thermophila 37.0 37.0 1 PMID:9726856 -1.10.3.2 * trametes cinnabarina 234.0 234.0 1 PMID:14600793 -1.10.3.2 * trametes hirsuta 978.34 669.1700000000001 2 PMID:19221878;PMID:33146857 -1.10.3.2 * trametes polyzona 60.8 60.8 1 PMID:23775771 -1.10.3.2 * trametes pubescens 18.54 18.54 1 PMID:23196221 -1.10.3.2 * trametes sanguinea 340.8 69.0 3 PMID:17186237;PMID:17216440 -1.10.3.2 * trametes sp. 670.0 71.6 11 PMID:12664149;PMID:23712478 -1.10.3.2 * trametes versicolor 91440.0 454.0 3 PMID:16410773;PMID:18688574;PMID:25272733 -1.10.3.2 * trichoderma harzianum 164.0 147.25 2 * -1.10.3.2 * trichophyton rubrum 300.0 300.0 1 * -1.10.3.2 * truncospora tephropora 181.0 181.0 1 PMID:17381747 -1.10.3.2 * uncultured bacterium 22.8 0.8800000000000001 4 PMID:34054745 -1.10.3.2 * volvariella volvacea 13.5 3.4 3 PMID:14717699 -1.10.3.3 * aspergillus flavus 11.56 11.56 1 PMID:32796622 -1.10.3.3 * cucurbita sp. 133.5 133.5 1 PMID:16579635 -1.10.3.4 * bauhinia monandra 56.1 56.1 1 PMID:4166439 -1.10.3.4 * streptomyces griseus 0.066 0.03300175 2 PMID:16282322 -1.10.3.5 * gallus sp. 0.185 0.185 1 PMID:4650602 -1.10.3.5 * mus musculus 0.16 0.16 1 PMID:4650602 -1.10.3.5 * ovis aries 0.24 0.24 1 PMID:4650602 -1.10.3.5 * rattus norvegicus 1.141 0.134 11 PMID:14347936;PMID:4650602;PMID:9870556 -1.10.3.6 * monocillium spp. 3.19 3.19 1 PMID:6825839 -1.10.5.1 * homo sapiens 242.0 242.0 1 PMID:9050836 -1.11.1.1 * clostridium acetobutylicum 0.993 0.342 4 PMID:19118342 -1.11.1.1 * enterococcus faecalis 115.0 100.5 2 PMID:2161844;PMID:8428993 -1.11.1.1 * enterococcus faecium 2.8e-05 2.8e-05 1 * -1.11.1.1 * lacticaseibacillus casei 2.96e-05 2.96e-05 1 * -1.11.1.1 * lacticaseibacillus rhamnosus 2.4e-05 2.4e-05 1 * -1.11.1.1 * lactiplantibacillus plantarum 2.1e-05 2.1e-05 1 * -1.11.1.1 * lactobacillus delbrueckii 0.00011 9.6e-05 2 * -1.11.1.1 * lentilactobacillus buchneri 2.2e-05 2.2e-05 1 * -1.11.1.1 * leuconostoc lactis 4.9e-05 4.9e-05 1 * -1.11.1.1 * leuconostoc mesenteroides 8.3e-05 8.2e-05 2 * -1.11.1.1 * levilactobacillus brevis 1e-05 1e-05 1 * -1.11.1.1 * liquorilactobacillus mali 2e-05 2e-05 1 * -1.11.1.1 * loigolactobacillus coryniformis 1.2e-05 1.2e-05 1 * -1.11.1.1 * pediococcus acidilactici 6.4e-06 6.4e-06 1 * -1.11.1.1 * pediococcus pentosaceus 3.2e-05 3.2e-05 1 * -1.11.1.1 * streptococcus thermophilus 4.4e-05 4.4e-05 1 * -1.11.1.10 * leptoxyphium fumago 2200.0 1900.0 2 PMID:566840;PMID:5949836 -1.11.1.10 * musa x paradisiaca 2.25 1.26 2 * -1.11.1.11 * alnus rubra 4.32 4.32 1 PMID:16665340 -1.11.1.11 * arabidopsis thaliana 53.0 27.5 4 PMID:18852264 -1.11.1.11 * arachis hypogaea 0.366 0.366 1 PMID:16665340 -1.11.1.11 * blastocrithidia nonstop 0.01 0.01 1 PMID:32344595 -1.11.1.11 * brassica rapa 56.0 56.0 1 * -1.11.1.11 * camellia sinensis 1500.0 800.0 2 PMID:9261100 -1.11.1.11 * chlamydomonas sp. 636.0 580.0 3 PMID:10729193 -1.11.1.11 * chlorella vulgaris 1307.0 655.15 2 PMID:9672748 -1.11.1.11 * crithidia thermophila 0.048 0.048 1 PMID:32344595 -1.11.1.11 * euglena gracilis 254.0 20.3 11 PMID:32344595;PMID:6768357;PMID:6772104 -1.11.1.11 * glycine max 63.6 31.85 8 PMID:16665340;PMID:8638916;PMID:9443387;PMID:9851828 -1.11.1.11 * helicoverpa zea 46.7 20.049999999999997 4 * -1.11.1.11 * lathyrus oleraceus 117.0 0.1305 4 PMID:16665340;PMID:8006006 -1.11.1.11 * leptomonas seymouri 0.039 0.039 1 PMID:32344595 -1.11.1.11 * lupinus albus 0.01 0.01 1 PMID:16665340 -1.11.1.11 * medicago sativa 0.11 0.11 1 PMID:16665340 -1.11.1.11 * musa x paradisiaca 2.64e-05 2.64e-05 1 PMID:30408454 -1.11.1.11 * novymonas esmeraldas 0.206 0.206 1 PMID:32344595 -1.11.1.11 * pallavicinia lyellii 456.0 228.8 2 PMID:20619666 -1.11.1.11 * raphanus sativus 561.1 561.1 1 * -1.11.1.11 * rhynchopus humris 0.01 0.01 1 PMID:32344595 -1.11.1.11 * ricinus communis 378.0 378.0 1 PMID:15639224 -1.11.1.11 * solanum tuberosum 36.0 36.0 1 * -1.11.1.11 * stylosanthes guianensis 0.45 0.32 24 * -1.11.1.11 * trifolium subterraneum 0.092 0.092 1 PMID:16665340 -1.11.1.11 * vicia faba 0.241 0.241 1 PMID:16665340 -1.11.1.11 * vicia sativa 0.213 0.213 1 PMID:16665340 -1.11.1.11 * vigna unguiculata 0.258 0.258 1 PMID:16665340 -1.11.1.12 * bos taurus 7.0 0.13 9 PMID:19345404;PMID:8436014 -1.11.1.12 * homo sapiens 336.0 19.5 14 PMID:17020817;PMID:24170573;PMID:29883798;PMID:7851631;PMID:9915822 -1.11.1.12 * rattus norvegicus 146300.0 28.3 15 PMID:16159880;PMID:18723092;PMID:2233312;PMID:7524677 -1.11.1.12 * schistosoma mansoni 90.0 45.016 2 PMID:8706688 -1.11.1.12 * sus scrofa 310.1 55.4 6 PMID:2233312;PMID:3978121;PMID:7066358 -1.11.1.13 * agrocybe praecox 128.0 128.0 1 * -1.11.1.13 * cerrena unicolor 112.4 112.4 1 * -1.11.1.13 * dichomitus squalens 3430.0 870.0 9 PMID:19381471;PMID:8917615 -1.11.1.13 * irpex lacteus 23.8 23.8 1 PMID:30019324 -1.11.1.13 * klebsiella pneumoniae 241.18 101.85 3 * -1.11.1.13 * lentinula edodes 660.0 0.32999999999999996 22 PMID:11425471;PMID:1366641;PMID:17583498 -1.11.1.13 * lentinus tigrinus 288.0 105.0 6 PMID:19578878 -1.11.1.13 * phanerodontia chrysosporium 484.8 82.5 8 PMID:1854201;PMID:2210334;PMID:24332478;PMID:3080953;PMID:3800395 -1.11.1.13 * pleurotus eryngii 187.0 178.5 2 PMID:8647081 -1.11.1.13 * pleurotus ostreatus 221.0 221.0 1 PMID:9165096 -1.11.1.13 * schizophyllum commune 506.0 506.0 1 * -1.11.1.13 * stropharia coronilla 692.0 692.0 1 * -1.11.1.14 * agaricus bisporus 0.77 0.41125 2 PMID:28912833 -1.11.1.14 * comamonas sp. 0.307 0.249 2 * -1.11.1.14 * gloeophyllum sepiarium 27.9 16.2 2 PMID:19916925 -1.11.1.14 * lenzites betulinus 29.58 29.58 1 PMID:23330392 -1.11.1.14 * loweporus lividus 3.68 3.68 1 * -1.11.1.14 * phanerodontia chrysosporium 28.0 14.2 10 PMID:16593451;PMID:18588065;PMID:3080953;PMID:4026322 -1.11.1.14 * pseudomonas fluorescens 13.79 13.79 1 PMID:32827973 -1.11.1.14 * streptomyces griseosporeus 5.75 5.75 1 PMID:25478960 -1.11.1.14 * trametes versicolor 553.0 14.350000000000001 4 PMID:22862820;PMID:8424685 -1.11.1.16 * bjerkandera sp. 80.0 80.0 1 PMID:9624124 -1.11.1.16 * meripilus vitreus 23.1 23.1 1 * -1.11.1.16 * pleurotus eryngii 194.0 9.2 8 PMID:10508113;PMID:11532015;PMID:22566208 -1.11.1.16 * pleurotus ostreatus 559.0 197.74 4 PMID:12396142;PMID:27129968 -1.11.1.16 * pleurotus sapidus 2.3 1.2999999999999998 4 * -1.11.1.16 * stereum ostrea 26.6 26.6 1 PMID:23124346 -1.11.1.18 * corallina officinalis 310.0 9.9 3 PMID:1426568;PMID:21046195;PMID:8132014 -1.11.1.18 * corallina pilulifera 376.8 376.8 1 PMID:12126706 -1.11.1.18 * ecklonia cava subsp. stolonifera 32.5 32.5 1 PMID:9861726 -1.11.1.18 * kitasatospora aureofaciens 248.6 31.665 8 PMID:1527491;PMID:1783900;PMID:31204052;PMID:3122838 -1.11.1.18 * streptomyces griseus 1.1 1.1 1 PMID:3151989 -1.11.1.18 * streptomyces venezuelae 963.0 482.385 2 PMID:2628543 -1.11.1.19 * anabaena sp. 1478.0 256.5 12 PMID:19801472 -1.11.1.19 * auricularia auricula-judae 469.0 347.8 3 PMID:19756587 -1.11.1.19 * bacillus subtilis 66.8 11.55 5 PMID:25650125 -1.11.1.19 * bjerkandera adusta 18.6 13.86 2 PMID:28813685 -1.11.1.19 * geotrichum candidum 331.0 39.7 4 PMID:10049859;PMID:10742277 -1.11.1.19 * irpex lacteus 37.8 37.8 1 PMID:23666335 -1.11.1.19 * saccharomonospora viridis 17.8 9.3 2 PMID:25333297 -1.11.1.19 * streptomyces albidoflavus 46.51 46.51 1 PMID:33051013 -1.11.1.19 * streptomyces avermitilis 3.08 1.551 2 PMID:28089379 -1.11.1.19 * thanatephorus cucumeris 834.0 147.5 12 PMID:15313183;PMID:16944133;PMID:17928290;PMID:19217546 -1.11.1.19 * xylaria grammica 51.0 27.2 2 PMID:34572604 -1.11.1.2 * desulfovibrio desulfuricans 39.6 37.45 2 PMID:16887686 -1.11.1.2 * treponema primitia 0.005 0.004 2 PMID:15006747 -1.11.1.20 * mus musculus 0.69 0.28 5 PMID:18006499 -1.11.1.20 * sus scrofa 0.062 0.057499999999999996 2 PMID:18006499 -1.11.1.21 * archaeoglobus fulgidus 6922.0 23.3 7 PMID:11699646;PMID:18178143 -1.11.1.21 * bacillus pumilus 55784.0 818.0 3 PMID:21996477;PMID:27016935 -1.11.1.21 * burkholderia pseudomallei 3630.0 1102.65 4 PMID:12454496;PMID:18178143 -1.11.1.21 * escherichia coli 2200.0 660.0 5 PMID:10801338;PMID:18178143 -1.11.1.21 * geobacillus stearothermophilus 3120.0 5.9 3 PMID:18178143 -1.11.1.21 * haloarcula marismortui 851.0 428.0 2 PMID:7947969 -1.11.1.21 * halobacterium salinarum 104.3 23.55 4 PMID:8320233 -1.11.1.21 * klebsiella pneumoniae 560.0 301.5 2 PMID:2029529 -1.11.1.21 * mycobacterium sp. 1145.0 584.6 2 PMID:14553939 -1.11.1.21 * mycobacterium tuberculosis 4500.0 16.4 14 PMID:10933818;PMID:18178143;PMID:9006925 -1.11.1.21 * mycolicibacterium smegmatis 533.0 267.75 2 PMID:7673210 -1.11.1.21 * neurospora crassa 14.9 14.9 1 PMID:29305053 -1.11.1.21 * oceanobacillus oncorhynchi subsp. incaldanensis 35000.0 3914.0 4 * -1.11.1.21 * penicillium simplicissimum 2960.0 77.0 7 PMID:8631329 -1.11.1.21 * rhodobacter capsulatus 4830.0 2.0 3 PMID:18178143 -1.11.1.21 * synechococcus elongatus pcc 7942 = fachb-805 785.0 394.7 2 PMID:9207193 -1.11.1.21 * synechocystis sp. 5420.0 4.65 12 PMID:10543446;PMID:12603334;PMID:12731870;PMID:15134453;PMID:18178143 -1.11.1.21 * synechocystis sp. pcc 6803 3.2 3.2 1 PMID:12731870;PMID:15134453 -1.11.1.22 * synechocystis sp. 0.15 0.084 10 PMID:11418106 -1.11.1.24 * rattus norvegicus 2.74 1.82 2 PMID:17974571 -1.11.1.24 * trichoderma reesei 28.0 20.25 2 PMID:33259843 -1.11.1.24 * xylella fastidiosa 1.76 1.49 3 PMID:20335172 -1.11.1.27 * rattus norvegicus 6.2 6.1 2 PMID:19236840 -1.11.1.3 * lathyrus oleraceus 2.9 2.9 1 PMID:10938370 -1.11.1.5 * acidithiobacillus thiooxidans 18.16 18.16 1 * -1.11.1.5 * geobacter sulfurreducens 26.4 26.4 1 PMID:19735665 -1.11.1.5 * marinobacter nauticus 104.6 58.75 2 PMID:10525144 -1.11.1.5 * pseudomonas aeruginosa 135.0 135.0 1 PMID:6307263 -1.11.1.6 * acinetobacter sp. ys0810 37318.0 37318.0 1 PMID:25045672 -1.11.1.6 * aspergillus nidulans 741.0 741.0 1 PMID:10858500 -1.11.1.6 * aspergillus niger 21400.0 21400.0 1 PMID:12054464 -1.11.1.6 * bacillus sp. (in: firmicutes) 55000.0 27500.47 2 PMID:15158713 -1.11.1.6 * bacillus subtilis 37000.0 35800.0 2 PMID:17876537;PMID:27151682 -1.11.1.6 * bacteroides fragilis 69100.0 69100.0 1 PMID:12054464 -1.11.1.6 * beta vulgaris subsp. cicla 56950.0 56950.0 1 PMID:11342285 -1.11.1.6 * bifidobacterium asteroides 6400.0 6400.0 1 PMID:23154971 -1.11.1.6 * bordetella pertussis 225000.0 225000.0 1 PMID:12054464 -1.11.1.6 * bos taurus 121000.0 106400.0 2 PMID:12054464;PMID:3019241 -1.11.1.6 * brucella abortus 145800.0 145800.0 1 PMID:12054464 -1.11.1.6 * canis lupus familiaris 73440.0 73440.0 1 PMID:10661897 -1.11.1.6 * capra capra 38330.0 38330.0 1 PMID:8302290 -1.11.1.6 * cereibacter sphaeroides 55930.0 55930.0 1 PMID:9575236 -1.11.1.6 * cytobacillus firmus 75000.0 8000.0 3 PMID:7748885 -1.11.1.6 * enterococcus faecalis 82.0 82.0 1 PMID:12399505 -1.11.1.6 * escherichia coli 20700.0 1486.0 3 PMID:12054464;PMID:374409 -1.11.1.6 * frankia sp. r43 234.8 4.462 8 * -1.11.1.6 * gallus gallus 560.0 560.0 1 * -1.11.1.6 * geobacillus sp. b1 40526.0 40526.0 1 PMID:27579320 -1.11.1.6 * haliotis discus discus 30000.0 30000.0 1 PMID:18187341 -1.11.1.6 * halobacterium salinarum 6422.0 104.3 3 PMID:7814327;PMID:8320233 -1.11.1.6 * helicobacter pylori 61400.0 61400.0 1 PMID:12054464 -1.11.1.6 * homo sapiens 273800.0 77.5 5 PMID:12054464;PMID:14710363;PMID:17408968 -1.11.1.6 * klebsiella pneumoniae 500000.0 500000.0 1 PMID:15132174 -1.11.1.6 * kloeckera sp. 282000.0 282000.0 1 PMID:3956497 -1.11.1.6 * komagataella pastoris 826000.0 826000.0 1 PMID:11421814 -1.11.1.6 * lathyrus oleraceus 953000.0 953000.0 1 PMID:10694065 -1.11.1.6 * listeria seeligeri 89300.0 89300.0 1 PMID:12054464 -1.11.1.6 * metallosphaera hakonensis 3667.0 3667.0 1 PMID:17983766 -1.11.1.6 * methanobrevibacter arboriphilus 120000.0 120000.0 1 PMID:11425719 -1.11.1.6 * methanosarcina barkeri 61500.0 61500.0 1 PMID:10382262 -1.11.1.6 * micrococcus luteus 109100.0 109100.0 1 PMID:12054464 -1.11.1.6 * mus musculus 8.0 5.75 2 PMID:14710363 -1.11.1.6 * mycobacterium sp. 1145.0 1145.0 1 PMID:14553939 -1.11.1.6 * mycothermus thermophilus 18710.0 4657.2 4 PMID:18369615;PMID:23545640;PMID:30289408 -1.11.1.6 * neurospora crassa 10200.0 1300.0 5 PMID:12033445;PMID:37891 -1.11.1.6 * oceanobacillus oncorhynchi 35000.0 17658.0 2 * -1.11.1.6 * ovis aries 1017.0 1017.0 1 * -1.11.1.6 * paracoccidioides brasiliensis 1134.0 750.3 2 PMID:19897569 -1.11.1.6 * petroselinum crispum 1126.0 1126.0 1 PMID:17516252 -1.11.1.6 * pigmentiphaga sp. dl-8 690000.0 690000.0 1 PMID:25665507 -1.11.1.6 * proteus mirabilis 160000.0 160000.0 1 PMID:12054464 -1.11.1.6 * pseudomonas aeruginosa 71800.0 71800.0 1 PMID:12054464 -1.11.1.6 * pseudomonas syringae 84600.0 42483.5 2 PMID:12054464;PMID:7546603 -1.11.1.6 * psychrobacter piscatorii 222000.0 120850.0 2 PMID:22408420 -1.11.1.6 * pyrobaculum calidifontis 23500.0 23500.0 1 PMID:12029047 -1.11.1.6 * rhodospirillum rubrum 39960.0 20608.0 2 PMID:16728955;PMID:18062223 -1.11.1.6 * saccharomyces cerevisiae 116100.0 116100.0 1 PMID:12054464 -1.11.1.6 * serratia marcescens 199600.0 98900.0 3 PMID:12054464;PMID:21077118 -1.11.1.6 * thermus brockianus 5320.0 5320.0 1 PMID:12892493 -1.11.1.6 * trigonopsis variabilis 55000.0 27558.5 2 * -1.11.1.6 * vibrio rumoiensis 395000.0 395000.0 1 PMID:10714995 -1.11.1.6 * vigna mungo 25700.0 25700.0 1 PMID:22341355 -1.11.1.6 * xanthomonas campestris 99900.0 50427.5 2 PMID:12054464;PMID:12520360 -1.11.1.6 * zavarzinia compransoris 3250.0 3250.0 1 * -1.11.1.7 * aedes aegypti 10.4 10.4 1 PMID:10871050 -1.11.1.7 * agaricales sp. 'arthromyces ramosus' 290.0 290.0 1 * -1.11.1.7 * anabaena sp. 283.0 144.3 2 PMID:19801472 -1.11.1.7 * arachis hypogaea 78.0 78.0 1 PMID:11419644 -1.11.1.7 * armoracia rusticana 1150.0 772.3 5 PMID:12628703;PMID:17284853;PMID:20681636 -1.11.1.7 * armoracia sp. 1420.0 1420.0 1 PMID:11419644 -1.11.1.7 * beta vulgaris 8.0 4.335 2 PMID:12358490 -1.11.1.7 * bos taurus 40.9 20.7 5 PMID:16212035;PMID:19149672;PMID:23122138 -1.11.1.7 * boucerosia umbellata 250.0 250.0 1 PMID:27714639 -1.11.1.7 * brassica oleracea 882.0 472.0 3 PMID:15826079 -1.11.1.7 * brassica oleracea var. capitata f. rubra 3550.0 3550.0 1 PMID:24879596 -1.11.1.7 * brassica rapa 3441.0 1783.0 2 PMID:20405843 -1.11.1.7 * calotropis procera 287.88 287.88 1 * -1.11.1.7 * camellia sinensis 151.0 151.0 1 PMID:9276947 -1.11.1.7 * capra hircus 5.3 5.3 1 PMID:18191143 -1.11.1.7 * capsicum annuum 8.9 6.4 2 * -1.11.1.7 * chromolaena odorata 8987.0 8987.0 1 PMID:16632882 -1.11.1.7 * cicer arietinum 2045.0 2045.0 1 PMID:17073725 -1.11.1.7 * cytisus multiflorus 17961.0 17961.0 1 PMID:25246165 -1.11.1.7 * elizabethkingia meningoseptica 51.0 51.0 1 PMID:10561543 -1.11.1.7 * glycine max 4565.0 3337.5 2 PMID:12628703 -1.11.1.7 * helianthus annuus 131.7 67.60499999999999 2 PMID:18586509 -1.11.1.7 * homo sapiens 2.05 2.05 1 PMID:949968 -1.11.1.7 * ipomoea batatas 5020.0 5020.0 1 PMID:11419644 -1.11.1.7 * leptogium saturninum 243.3 5.3 11 PMID:22056522 -1.11.1.7 * nicotiana sylvestris 1680.0 1680.0 1 PMID:11419644 -1.11.1.7 * nicotiana tabacum 1100.0 1100.0 1 PMID:14640960 -1.11.1.7 * plasmodium falciparum 5.08 5.08 1 PMID:15802233 -1.11.1.7 * pleurotus ostreatus 6.0 6.0 1 PMID:16535590 -1.11.1.7 * pyrococcus furiosus 36.0 36.0 1 PMID:15547260 -1.11.1.7 * raphanus sativus var. niger 166.7 166.7 1 PMID:35064889 -1.11.1.7 * solanum lycopersicum 10.0 10.0 1 PMID:14521509 -1.11.1.7 * thermothelomyces thermophilus 178.0 1.545 6 PMID:26047916 -1.11.1.7 * trachycarpus fortunei 6230.0 3171.0 2 PMID:17177516;PMID:28523913 -1.11.1.7 * vigna radiata 85.4 85.4 1 PMID:27976372 -1.11.1.8 * bos taurus 464.0 464.0 1 PMID:6503722 -1.11.1.8 * capra hircus 31.0 31.0 1 PMID:4204720 -1.11.1.8 * homo sapiens 381.0 180.0 3 PMID:25576858;PMID:28778521;PMID:2995127 -1.11.1.8 * sus scrofa 138.0 85.0 2 PMID:12325367;PMID:6503722 -1.11.1.9 * aloe vera 350.0 350.0 1 PMID:8193675 -1.11.1.9 * camelus dromedarius 12.09 12.09 1 * -1.11.1.9 * cryptosporidium parvum 84.3 84.3 1 PMID:24477026 -1.11.1.9 * cyberlindnera mrakii 1300.0 309.0 4 PMID:8541308 -1.11.1.9 * drosophila melanogaster 14.38 14.38 1 PMID:18500926 -1.11.1.9 * gallus gallus 70.3 70.3 1 PMID:8842471 -1.11.1.9 * homo sapiens 215.0 5.5 7 PMID:10207030;PMID:16887253;PMID:8204670 -1.11.1.9 * hyalomma dromedarii 56.3 49.25 2 * -1.11.1.9 * mesocricetus auratus 488.0 488.0 1 PMID:6227287 -1.11.1.9 * oryctolagus cuniculus 291.0 291.0 1 PMID:10549853 -1.11.1.9 * ovis aries 1407.0 1407.0 1 PMID:6094966 -1.11.1.9 * rattus norvegicus 1852.0 202.12 12 PMID:16887253;PMID:9030530 -1.11.1.9 * saccharomyces cerevisiae 445.0 445.0 1 PMID:34580743 -1.11.1.9 * thunnus maccoyii 256.0 256.0 1 * -1.11.1.9 * trypanosoma cruzi 0.6868 0.16 3 PMID:11842085;PMID:12049643 -1.11.2.1 * candolleomyces aberdarensis 205.9 144.4 2 PMID:34288703 -1.11.2.1 * coprinellus radians 38.5 31.5 5 PMID:17601809;PMID:19823936 -1.11.2.1 * cyclocybe aegerita 354.3 101.3 20 PMID:15294788;PMID:17410351;PMID:18815784;PMID:19022254;PMID:19585533;PMID:19713216;PMID:19823936;PMID:20470751;PMID:29604496 -1.11.2.1 * marasmius rotula 26.0 26.0 1 PMID:29604496 -1.11.2.3 * lathyrus oleraceus 3.4 1.97 2 PMID:468835 -1.12.1.2 * achromobacter denitrificans 7.7 7.7 1 PMID:9042758 -1.12.1.2 * achromobacter ruhlandii 34.0 34.0 1 PMID:9042758 -1.12.1.2 * caldanaerobacter subterraneus subsp. tengcongensis 1700.0 10.0 5 PMID:15256587 -1.12.1.2 * cupriavidus necator 2030.0 57.0 17 PMID:10682839;PMID:14606942;PMID:15164270;PMID:15838039;PMID:186126;PMID:226163;PMID:23861944;PMID:9042758 -1.12.1.2 * frankia sp. 4.91 0.205 4 PMID:15696261 -1.12.1.2 * frankia sp. r43 0.0018 0.0012 2 PMID:15251202 -1.12.1.2 * gloeocapsa alpicola 9.8 9.8 1 PMID:17223791 -1.12.1.2 * hydrogenomonas sp. 36.5 36.5 1 PMID:4394007 -1.12.1.2 * methylococcus capsulatus 0.0255 0.00775 8 PMID:11807566 -1.12.1.2 * rhodococcus opacus 103.0 58.5 4 PMID:11807565;PMID:4374147;PMID:9042758 -1.12.1.2 * synechocystis sp. 87.78 41.0 4 PMID:12034472;PMID:19801638 -1.12.1.2 * thermococcus stetteri 430.0 430.0 1 * -1.12.1.3 * synechocystis sp. 87.78 43.928 2 PMID:19801638 -1.12.1.4 * neomoorella thermoacetica 195.0 57.5 3 PMID:23316038 -1.12.1.4 * ruminococcus albus 60.0 60.0 1 PMID:25157086 -1.12.1.5 * pyrococcus furiosus 126.0 7.96 3 PMID:22157005 -1.12.2.1 * bacteria 35340.0 19578.5 2 * -1.12.2.1 * desulfovibrio desulfuricans 250.0 160.0 2 PMID:6096145;PMID:6303306 -1.12.5.1 * wolinella succinogenes 505.0 505.0 1 PMID:1587288;PMID:8319698 -1.12.7.2 * acidithiobacillus ferrooxidans 6.02 6.02 1 PMID:8661919 -1.12.7.2 * alvikia littoralis 75.7 75.7 1 PMID:9989593 -1.12.7.2 * caldanaerobacter subterraneus subsp. tengcongensis 1260.0 391.0 3 PMID:15256587 -1.12.7.2 * chlamydomonas reinhardtii 1800.0 1367.5 2 PMID:16663691;PMID:8513797 -1.12.7.2 * clostridium acetobutylicum 28.0 28.0 1 PMID:18320190 -1.12.7.2 * clostridium pasteurianum 17600.0 96.3 10 PMID:16887509;PMID:4433567;PMID:6331453;PMID:7020766;PMID:728150 -1.12.7.2 * cupriavidus necator 121.0 121.0 1 PMID:6351840 -1.12.7.2 * enterobacter cloacae 335.0 167.63 2 * -1.12.7.2 * megasphaera elsdenii 1470.0 990.0 2 PMID:527582 -1.12.7.2 * methanosarcina barkeri 210.0 71.5 10 PMID:10491189 -1.12.7.2 * nitratidesulfovibrio vulgaris 174.0 131.5 2 PMID:9367885 -1.12.7.2 * pyrococcus furiosus 131.0 5.19 8 PMID:10714990;PMID:10852873 -1.12.7.2 * sporomusa sphaeroides 19.8 19.8 1 PMID:8593101 -1.12.7.2 * tetradesmus obliquus 700.0 700.0 1 PMID:11096090 -1.12.7.2 * tetraselmis sp. ksn-2002 50.0 25.0535 2 PMID:17321121 -1.12.98.1 * methanobacterium bryantii 0.155 0.0782 2 * -1.12.98.1 * methanobacterium formicicum 172.0 63.2 7 PMID:2738024;PMID:6375661 -1.12.98.1 * methanocaldococcus jannaschii 16.0 10.6 2 PMID:16348172 -1.12.98.1 * methanococcus voltae 364.0 197.5 4 PMID:11054113;PMID:3121317 -1.12.98.1 * methanosarcina barkeri 82.8 5.9685 4 PMID:2550229;PMID:8521835 -1.12.98.1 * methanospirillum hungatei 11.1 5.9735 2 * -1.12.98.1 * methanothermobacter thermautotrophicus 49.0 49.0 1 PMID:3663585 -1.12.98.2 * methanopyrus kandleri 360.0 360.0 1 PMID:1772345 -1.12.98.2 * methanothermobacter marburgensis 1250.0 930.0 2 PMID:14686932;PMID:1521540 -1.12.98.2 * methanothermobacter thermautotrophicus 800.0 775.0 2 PMID:1765081 -1.12.98.2 * methanothermococcus thermolithotrophicus 440.0 440.0 1 PMID:8599536 -1.12.98.4 * desulfomicrobium baculatum 0.043 0.043 1 * -1.12.98.4 * desulfuromonas acetoxidans 0.026 0.026 1 * -1.12.98.4 * desulfuromusa succinoxidans 0.04 0.04 1 * -1.12.98.4 * pyrodictium abyssi 7.56 7.56 1 PMID:11265482;PMID:9546664 -1.12.98.4 * sulfurospirillum deleyianum 0.27 0.27 1 * -1.12.98.4 * thermophilic iron-oxidizing bacterium strain ti-1 2.73 2.73 1 PMID:9614700 -1.12.98.4 * trichloromonas acetexigens 0.07 0.07 1 * -1.12.98.4 * wolinella succinogenes 732.0 525.0 4 * -1.12.99.6 * acidianus ambivalens 624.0 369.0 2 PMID:12949162 -1.12.99.6 * aeropyrum camini 14.8 14.7 2 PMID:19716518 -1.12.99.6 * afipia carboxidovorans 173.0 173.0 1 PMID:9324252 -1.12.99.6 * allochromatium vinosum 300.0 300.0 1 PMID:15157115 -1.12.99.6 * chlamydomonas reinhardtii 650.0 605.0 4 PMID:19397274 -1.12.99.6 * cupriavidus necator 0.942 0.942 1 PMID:11278570 -1.12.99.6 * desulfomicrobium norvegicum 205.0 183.0 2 PMID:12861426 -1.12.99.6 * desulfovibrio multispirans 792.0 792.0 1 PMID:6097250 -1.12.99.6 * escherichia coli 10.6 5.3175 2 PMID:17668201;PMID:3516689 -1.12.99.6 * hydrogenibacillus schlegelii 84.0 42.2 2 * -1.12.99.6 * hydrogenimonas thermophila 1078.0 199.5 6 PMID:20699572 -1.12.99.6 * hydrogenobacter thermophilus 285.0 142.53065 2 PMID:10803945 -1.12.99.6 * hydrogenophaga sp. 110.0 110.0 1 PMID:19025569 -1.12.99.6 * methanocaldococcus jannaschii 150.0 150.0 1 PMID:17924153 -1.12.99.6 * methanosarcina barkeri 90.0 70.0 2 PMID:10491189 -1.12.99.6 * nitratidesulfovibrio vulgaris 50000.0 4006.0 4 PMID:12861426;PMID:7652207 -1.12.99.6 * persephonella hydrogeniphila 50.0 50.0 1 PMID:19716518 -1.12.99.6 * pyrococcus furiosus 360.0 360.0 1 PMID:2538471 -1.12.99.6 * solidesulfovibrio fructosivorans 80.0 80.0 2 PMID:12861426 -1.12.99.6 * tetraselmis sp. ksn-2002 50.0 25.0535 2 PMID:17321121 -1.12.99.6 * thermoanaerobacterium saccharolyticum 1.92 1.92 1 PMID:19648238 -1.12.99.6 * thermodesulfobacterium thermophilum 783.0 783.0 1 PMID:1317168 -1.13.11.1 * acinetobacter calcoaceticus 20.0 20.0 1 PMID:58860 -1.13.11.1 * acinetobacter radioresistens 24.5 24.5 1 PMID:9369233 -1.13.11.1 * acinetobacter sp. y64 15.13 8.275 2 PMID:26563518 -1.13.11.1 * arthrobacter citreus 0.002 0.002 1 PMID:16453171 -1.13.11.1 * arthrobacter sp. 41.0 39.0 4 PMID:9760749 -1.13.11.1 * burkholderia sp. 3.92 2.0074 2 PMID:12270830 -1.13.11.1 * candida albicans 63.0 63.0 1 PMID:17089147 -1.13.11.1 * corynebacterium glutamicum 5.4 0.16 3 PMID:15168857 -1.13.11.1 * cupriavidus necator 9.36 0.3 4 PMID:8215795;PMID:8661943 -1.13.11.1 * cutaneotrichosporon cutaneum 18.15 18.15 1 * -1.13.11.1 * geobacillus sp. 7.42 7.42 1 * -1.13.11.1 * priestia megaterium 0.355 0.355 1 PMID:803956 -1.13.11.1 * pseudomonas aeruginosa 10.0 0.1915 4 PMID:18331335 -1.13.11.1 * pseudomonas putida 672.0 14.95 6 PMID:14599591;PMID:18836712 -1.13.11.1 * pseudomonas reinekei 35.8 4.1 8 PMID:17172348 -1.13.11.1 * pseudomonas sp. 20.0 0.348 5 PMID:697765 -1.13.11.1 * rhizobium leguminosarum 51.1 28.675 2 PMID:16348234 -1.13.11.1 * rhodococcus erythropolis 24.0 24.0 1 * -1.13.11.1 * rhodococcus opacus 37.65 37.65 1 * -1.13.11.1 * rhodococcus rhodochrous 14.3 14.3 1 * -1.13.11.1 * rhodococcus sp. (in: high g+c gram-positive bacteria) 35.0 34.5 2 PMID:16233669 -1.13.11.1 * sphingobium xenophagum 1.14 0.5 3 * -1.13.11.1 * stenotrophomonas maltophilia 11.97 0.575 4 PMID:24031359 -1.13.11.1 * stutzerimonas stutzeri 15.0 15.0 1 PMID:32582076 -1.13.11.12 * burkholderia thailandensis 26.4 16.55 4 PMID:25586578 -1.13.11.12 * glycine max 3.0 1.52 2 PMID:32732043 -1.13.11.12 * lasiodiplodia theobromae 15733.3 10635.65 2 PMID:25326184 -1.13.11.12 * olea europaea 564.0 23.4 5 PMID:18790508;PMID:19268561 -1.13.11.12 * pseudomonas aeruginosa 28.3 28.3 1 PMID:23064455 -1.13.11.14 * pseudomonas putida 0.135 0.115 2 PMID:4041238 -1.13.11.14 * pseudomonas sp. 0.508 0.3095 4 * -1.13.11.15 * arthrobacter globiformis 0.01 0.01 1 PMID:9047314 -1.13.11.15 * arthrobacter synephrinum 2.51 2.51 1 PMID:588248 -1.13.11.15 * brevibacterium fuscum 6.2 6.2 1 PMID:9179284 -1.13.11.15 * escherichia coli 100.0 100.0 1 PMID:2261999 -1.13.11.15 * geobacillus stearothermophilus 0.25 0.25 1 PMID:838683 -1.13.11.15 * klebsiella pneumoniae 102.0 102.0 1 * -1.13.11.15 * pseudomonas aeruginosa 44.3 44.3 1 PMID:28158217 -1.13.11.16 * cupriavidus necator 4.3 4.3 1 PMID:8752345 -1.13.11.16 * escherichia coli 47.9 47.9 1 PMID:8399388 -1.13.11.17 * jasminum grandiflorum 0.00575 0.00575 1 * -1.13.11.17 * tecoma stans 0.0157 0.0157 1 PMID:16662784 -1.13.11.17 * zea mays 0.0441 0.0441 1 * -1.13.11.18 * acidianus brierleyi 0.91 0.91 1 * -1.13.11.18 * acidianus sp. 186.7 186.7 1 PMID:12664265 -1.13.11.18 * acidithiobacillus caldus 2336.0 1223.75 2 PMID:24893664;PMID:30072973 -1.13.11.18 * acidithiobacillus ferrooxidans 1484.0 1484.0 1 PMID:24893664 -1.13.11.18 * arabidopsis thaliana 7.95 7.95 1 PMID:22786886 -1.13.11.18 * homo sapiens 113.0 113.0 1 PMID:29980601 -1.13.11.18 * thiobacillus denitrificans 0.000952 0.000652 2 * -1.13.11.18 * thiobacillus thioparus 0.25 0.25 1 PMID:5968172 -1.13.11.19 * equus caballus 3.24 3.12 2 * -1.13.11.19 * mus musculus 9.1e-05 6.4e-05 2 PMID:17153586 -1.13.11.19 * rattus norvegicus 6.2e-05 2.6e-05 3 PMID:17153586 -1.13.11.19 * sus scrofa 2.8 2.8 1 PMID:3657558 -1.13.11.2 * arthrobacter citreus 0.054 0.054 1 PMID:16453171 -1.13.11.2 * halalkalibacterium ligniniphilum 0.0082 0.0082 1 PMID:34907211 -1.13.11.2 * planococcus sp. (in: firmicutes) 0.01973 0.01973 1 PMID:23921803 -1.13.11.2 * planococcus sp. s5 0.0214 0.014645 8 PMID:25337606 -1.13.11.2 * pseudomonas aeruginosa 90.0 62.5 2 PMID:2126328 -1.13.11.2 * pseudomonas putida 802.0 81.15 12 PMID:14087325;PMID:18023805;PMID:18836712;PMID:20038148;PMID:7096306;PMID:7629031;PMID:7710322;PMID:7928969 -1.13.11.2 * pseudomonas putida mt-2 320.0 320.0 1 PMID:6826545 -1.13.11.2 * pseudomonas sp. 593.0 68.0 7 PMID:14600239;PMID:15730028 -1.13.11.2 * stenotrophomonas maltophilia 936.3 0.37 7 PMID:24031359 -1.13.11.2 * thauera sp. k11 27.2 27.2 1 PMID:29380863 -1.13.11.20 * bacillus cereus 4.4 4.4 1 PMID:16855246 -1.13.11.20 * bacillus subtilis 1.0 1.0 1 PMID:16855246 -1.13.11.20 * cupriavidus necator 0.05 0.05 1 PMID:26590284 -1.13.11.20 * rattus norvegicus 1.4 0.000465 10 PMID:16325423;PMID:16855246;PMID:16856322;PMID:7722697 -1.13.11.20 * streptomyces coelicolor 0.8 0.75 2 PMID:16855246 -1.13.11.20 * trichophyton mentagrophytes 0.034 0.034 1 PMID:21039937 -1.13.11.23 * uncultured bacterium 13.0 13.0 1 PMID:5652436 -1.13.11.24 * aspergillus flavus 180.0 180.0 1 PMID:5555519 -1.13.11.24 * aspergillus japonicus 90.0 90.0 1 PMID:12071961 -1.13.11.24 * aspergillus niger 55.7 55.7 1 PMID:10469153 -1.13.11.24 * bacillus subtilis 2.49 1.685 6 PMID:15039076;PMID:20460727 -1.13.11.24 * penicillium olsonii 175.0 175.0 1 PMID:18206655 -1.13.11.24 * streptomyces sp. 144.0 28.0 3 PMID:18950192 -1.13.11.24 * streptomyces sp. fla 137.0 24.0 4 PMID:25903361 -1.13.11.25 * prescottella equi 22.17 22.17 1 PMID:5506273 -1.13.11.27 * arabidopsis thaliana 0.17 0.11 3 PMID:16163828 -1.13.11.27 * daucus carota 2.33 1.465 2 PMID:10858299 -1.13.11.27 * gallus gallus 8.5 8.5 1 PMID:1158879;PMID:3037256 -1.13.11.27 * homo sapiens 2.8 1.565 4 PMID:17613;PMID:23950902;PMID:873932 -1.13.11.27 * pseudomonas sp. 1.0 0.96 2 PMID:3037255;PMID:889802 -1.13.11.27 * streptomyces avermitilis 10.6 10.6 1 PMID:12590595 -1.13.11.27 * sus scrofa 51.0 45.3 2 PMID:3298972;PMID:7103516 -1.13.11.29 * stizolobium hassjoo 0.06 0.06 1 PMID:624278 -1.13.11.3 * acinetobacter calcoaceticus 20.0 20.0 1 PMID:1252412 -1.13.11.3 * acinetobacter lwoffii 5.23 5.23 1 PMID:12127980 -1.13.11.3 * agrobacterium tumefaciens 105.0 60.85 2 PMID:8772173 -1.13.11.3 * aspergillus niger 4.7 4.7 1 PMID:31540981 -1.13.11.3 * azotobacter vinelandii 46.69 46.69 1 PMID:6766312 -1.13.11.3 * brevibacterium fuscum 41.0 37.0 2 PMID:2280720;PMID:6323474 -1.13.11.3 * buttiauxella sp. s19-1 2.46 2.46 1 PMID:34678927 -1.13.11.3 * ectopseudomonas oleovorans 121.7 121.7 1 * -1.13.11.3 * geobacillus sp. 350.0 192.1 2 * -1.13.11.3 * hydrogenophaga palleronii 5.2 5.2 1 PMID:8772173 -1.13.11.3 * pleurotus ostreatus 0.39 0.365 2 * -1.13.11.3 * pseudomonas aeruginosa 61.6 61.6 1 PMID:4967959;PMID:5086950 -1.13.11.3 * pseudomonas fluorescens 33.45 33.45 1 PMID:13211618 -1.13.11.3 * pseudomonas putida 37.2 37.2 1 PMID:9485360 -1.13.11.3 * roseobacter sp. 0.88 0.73 3 PMID:11055908 -1.13.11.3 * sagittula stellata 0.46 0.28650000000000003 2 PMID:11055908 -1.13.11.3 * stenotrophomonas maltophilia 8.7 6.37 3 PMID:24031359 -1.13.11.3 * tecoma stans 0.0081 0.0081 1 * -1.13.11.30 * stizolobium hassjoo 0.031 0.031 1 PMID:624278 -1.13.11.31 * bos taurus 0.7 0.0018 5 PMID:2295656;PMID:3190246;PMID:6813645 -1.13.11.31 * homo sapiens 0.3 0.3 1 PMID:1851637 -1.13.11.31 * rattus norvegicus 0.34 0.34 1 PMID:6407525 -1.13.11.31 * sus scrofa 51.8 8.0 5 PMID:1652456;PMID:17442494;PMID:19683507;PMID:8031130;PMID:9184149 -1.13.11.33 * homo sapiens 2.125 2.125 1 PMID:3337718 -1.13.11.33 * oryctolagus cuniculus 93.5 47.084 2 PMID:17442494;PMID:6813644 -1.13.11.34 * cavia porcellus 0.0069 0.0069 1 PMID:3091590 -1.13.11.34 * homo sapiens 0.006 0.006 1 PMID:1848236 -1.13.11.34 * solanum tuberosum 147.0 17.799999999999997 4 PMID:17442494;PMID:2233349 -1.13.11.34 * sus scrofa 1.0 1.0 1 PMID:2233351 -1.13.11.34 * tulipa hybrid cultivar 5.2 5.2 1 PMID:3144972 -1.13.11.35 * azotobacter vinelandii 1780.0 1780.0 1 PMID:7217008 -1.13.11.36 * phenylobacterium immobile 8.15 8.15 1 * -1.13.11.37 * azotobacter sp. 7.06 7.06 1 PMID:16535063 -1.13.11.37 * cutaneotrichosporon cutaneum 140.0 70.113 2 PMID:571434;PMID:6539772 -1.13.11.37 * pseudarthrobacter chlorophenolicus 795.6 391.0 10 * -1.13.11.37 * pseudomonas sp. 0.45 0.41000000000000003 2 PMID:19149164 -1.13.11.37 * streptomyces rochei 27.0 27.0 1 PMID:7798136 -1.13.11.38 * nocardioides sp. 1567.0 180.0 4 PMID:9335300;PMID:9525941;PMID:9922237 -1.13.11.38 * pseudomonas sp. 61.5 29.0 5 PMID:19574301 -1.13.11.39 * bacillus sp. (in: firmicutes) 5.47 5.47 1 PMID:12672826 -1.13.11.39 * burkholderia cepacia 431.0 431.0 1 PMID:9857017 -1.13.11.39 * comamonas testosteroni 4.9 4.9 1 PMID:10777527 -1.13.11.39 * dyella ginsengisoli 118.3 64.52 2 PMID:19187202 -1.13.11.39 * ectopseudomonas oleovorans 87.2 87.2 1 PMID:3100508 -1.13.11.39 * pseudomonas putida 380.0 218.65 2 PMID:8633883 -1.13.11.39 * pseudomonas sp. 191.0 191.0 1 PMID:8428946 -1.13.11.39 * pseudomonas sp. sa-6 0.25 0.25 1 PMID:18248454 -1.13.11.39 * ralstonia sp. 6.88 1.88 9 PMID:15715866 -1.13.11.39 * ralstonia sp. sa-4 0.1 0.1 1 PMID:18248454 -1.13.11.39 * rhodococcus globerulus 30.0 20.0 3 PMID:12700274 -1.13.11.39 * rhodococcus sp. (in: high g+c gram-positive bacteria) 22.2 22.2 1 PMID:8702287 -1.13.11.39 * sphingomonas sp. 3.1 3.1 1 PMID:10438749 -1.13.11.4 * aquipseudomonas alcaligenes 23.2 0.635 6 PMID:10049846;PMID:12909360 -1.13.11.4 * comamonas testosteroni 498.0 498.0 1 PMID:2156846 -1.13.11.4 * delftia acidovorans 484.0 484.0 1 PMID:2156846 -1.13.11.4 * faucicola osloensis 12.0 12.0 1 PMID:234947 -1.13.11.4 * haloferax sp. 1.5 1.4 3 PMID:10086844 -1.13.11.4 * klebsiella pneumoniae 1040.0 1040.0 1 PMID:2256782 -1.13.11.4 * pseudaminobacter salicylatoxidans 1.18 1.18 1 PMID:11698383 -1.13.11.4 * pseudomonas putida 43.14 21.93 2 PMID:10049846 -1.13.11.4 * rhizorhabdus dicambivorans 15.4 8.0 2 PMID:32786824 -1.13.11.4 * rhodococcus sp. (in: high g+c gram-positive bacteria) 145.0 145.0 1 PMID:21181154 -1.13.11.40 * plexaura homomalla 352.0 352.0 1 PMID:8702854 -1.13.11.41 * alcaligenes sp. 3.4 3.125 2 PMID:10567221;PMID:3814084 -1.13.11.41 * burkholderia sp. 0.33 0.186 2 PMID:22451401 -1.13.11.43 * sphingomonas paucimobilis 0.0024 0.00225 2 PMID:15784996 -1.13.11.45 * gaeumannomyces graminis 18.0 18.0 1 PMID:15629124 -1.13.11.45 * pyricularia oryzae 2.01 2.01 1 PMID:26264916 -1.13.11.47 * arthrobacter sp. 70.7 70.7 1 PMID:8856057 -1.13.11.47 * pseudomonas putida 13.1 11.5 2 PMID:1515060;PMID:8856057 -1.13.11.48 * arthrobacter sp. 70.7 70.7 1 PMID:8856057 -1.13.11.48 * paenarthrobacter nitroguajacolicus 70.0 70.0 1 PMID:18549245 -1.13.11.49 * alicycliphilus denitrificans 22.0 13.85 2 PMID:18791031 -1.13.11.49 * alicycliphilus sp. 22.0 13.85 2 PMID:18791031 -1.13.11.49 * azospira oryzae 1500.0 8.27 5 PMID:19361444;PMID:32246282;PMID:8929278 -1.13.11.49 * ideonella dechloratans 2800.0 2800.0 1 PMID:11472023 -1.13.11.49 * stutzerimonas chloritidismutans 4650.0 225.35 4 PMID:19228194;PMID:19352644 -1.13.11.5 * agave toumeyana 0.625 0.625 1 PMID:4152877 -1.13.11.5 * agrostemma githago 0.405 0.405 1 PMID:4152877 -1.13.11.5 * aspergillus nidulans 0.75 0.75 1 PMID:9056215 -1.13.11.5 * aspergillus niger 5.17 5.17 1 * -1.13.11.5 * coleus scutellarioides 2.59 2.59 1 PMID:4152877 -1.13.11.5 * daucus carota 0.25 0.25 1 PMID:4152877 -1.13.11.5 * glycine max 0.495 0.495 1 PMID:4152877 -1.13.11.5 * homo sapiens 28.3 24.616 2 PMID:15479158;PMID:28869836 -1.13.11.5 * melilotus albus 0.125 0.125 1 PMID:4152877 -1.13.11.5 * nicotiana sylvestris 1.16 1.16 1 PMID:4152877 -1.13.11.5 * phaseolus vulgaris 0.515 0.515 1 PMID:4152877 -1.13.11.5 * pimpinella anisum 0.17 0.17 1 PMID:4152877 -1.13.11.5 * pseudomonas fluorescens 8.25 8.25 1 PMID:5954067 -1.13.11.5 * ruta graveolens 0.39 0.39 1 PMID:4152877 -1.13.11.50 * acinetobacter johnsonii 7.0 1.34 3 PMID:12237107;PMID:15803313;PMID:18973472 -1.13.11.52 * anopheles gambiae 1.43 1.43 1 PMID:18687401 -1.13.11.52 * brevibacillus brevis 3.85 3.85 1 PMID:6712960 -1.13.11.52 * delftia acidovorans 21.2 19.1 2 PMID:4307451 -1.13.11.52 * homo sapiens 4.7 0.072 21 PMID:10564724;PMID:10833386;PMID:11180976;PMID:11912287;PMID:15358362;PMID:15636586;PMID:18274832;PMID:2428037 -1.13.11.52 * meriones unguiculatus 0.905 0.134 6 PMID:10719243 -1.13.11.52 * mus musculus 104.9 0.735 37 PMID:18274832;PMID:2419335;PMID:6783035 -1.13.11.52 * oryctolagus cuniculus 234.0 0.11499999999999999 12 PMID:26687 -1.13.11.52 * priestia megaterium 23.5 19.15 4 PMID:803956 -1.13.11.52 * pseudomonas fluorescens 5.3 5.3 1 * -1.13.11.52 * rattus norvegicus 3.08 0.000277 13 PMID:10719243;PMID:4626718;PMID:5074346 -1.13.11.53 * klebsiella pneumoniae 18.2 18.2 1 PMID:8407993 -1.13.11.55 * acidianus ambivalens 11.52 7.395 6 PMID:15970399;PMID:2493451 -1.13.11.55 * acidianus sp. 186.7 186.7 1 PMID:12664265 -1.13.11.55 * acidianus tengchongensis 753000.0 4800.0 12 PMID:11111027;PMID:15691910 -1.13.11.55 * aquifex aeolicus 5.0 5.0 1 PMID:18060346 -1.13.11.55 * sulfobacillus acidophilus 17.17 8.690000000000001 2 PMID:23726793 -1.13.11.55 * sulfobacillus thermosulfidooxidans 0.22 0.135 4 PMID:27682113 -1.13.11.55 * sulfurisphaera tokodaii 10.5 5.725 2 PMID:32775998 -1.13.11.55 * thioalkalivibrio paradoxus 308.0 154.015 2 PMID:27920296 -1.13.11.56 * sphingobium xenophagum 83.36 83.36 1 PMID:2050635 -1.13.11.56 * stenotrophomonas sp. 0.17 0.15500000000000003 2 PMID:19543983 -1.13.11.57 * pseudomonas putida 42.7 32.05 2 PMID:16030014 -1.13.11.58 * musa acuminata 493.0 493.0 1 PMID:16608245 -1.13.11.6 * bos taurus 140.0 127.85 2 PMID:12672479;PMID:1387 -1.13.11.6 * mus musculus 6.8 6.8 1 PMID:10037484 -1.13.11.6 * papio ursinus 7.8 7.8 1 * -1.13.11.6 * pseudomonas fluorescens 7.9 7.9 1 PMID:12620844 -1.13.11.6 * rattus norvegicus 7.5 0.0075 3 PMID:3112306 -1.13.11.60 * aspergillus nidulans 3.2 3.2 1 PMID:19286665 -1.13.11.60 * colletotrichum gloeosporioides 1.39 0.87 9 PMID:26577673 -1.13.11.60 * gaeumannomyces graminis 1.8 1.8 1 PMID:8662736 -1.13.11.61 * nostoc sp. 18.4 6.3 3 PMID:26379279 -1.13.11.61 * nostoc sp. pcc 7120 = fachb-418 18.4 6.3 3 * -1.13.11.62 * aspergillus nidulans 0.761 0.2965 4 PMID:27129531 -1.13.11.63 * gallus gallus 0.32 0.16 3 PMID:18979213 -1.13.11.63 * homo sapiens 1.97 0.9861 2 PMID:18154347;PMID:24187135 -1.13.11.63 * mus musculus 0.51 0.51 1 PMID:17687551 -1.13.11.63 * oryctolagus cuniculus 3.5e-05 3.5e-05 1 PMID:4625243 -1.13.11.66 * cupriavidus necator 3.1 3.1 1 PMID:20386911 -1.13.11.66 * pseudomonas fluorescens 5.89 5.89 1 PMID:18502867 -1.13.11.66 * sphingomonas paucimobilis 0.88 0.575 2 PMID:10542173 -1.13.11.66 * sphingomonas sp. 6.1 6.1 2 PMID:21906340 -1.13.11.67 * oryctolagus cuniculus 2e-05 1.1500000000000002e-05 2 PMID:9331970 -1.13.11.67 * rattus norvegicus 2e-06 1.5e-06 2 PMID:9331970 -1.13.11.71 * saccharomyces cerevisiae 0.38 0.38 1 PMID:26026965 -1.13.11.74 * ectopseudomonas oleovorans 21.6 11.55 2 PMID:8892823 -1.13.11.75 * synechocystis sp. pcc 6803 0.47 0.47 1 PMID:24648526 -1.13.11.76 * comamonas testosteroni 29.7 29.7 1 PMID:15580337 -1.13.11.77 * nostoc punctiforme 0.345 0.236 3 PMID:27654823 -1.13.11.8 * brevibacterium fuscum 50.0 50.0 1 PMID:7142106 -1.13.11.8 * comamonas testosteroni 212.0 106.05 2 PMID:15650824;PMID:2280721;PMID:6317682 -1.13.11.8 * pseudomonas sp. k82 0.14 0.14 1 PMID:15357311 -1.13.11.8 * rhizobium leguminosarum 321.0 321.0 1 * -1.13.11.85 * piscinibacter gummiphilus 0.1 0.1 1 PMID:30215127 -1.13.11.85 * xanthomonas sp. 4.6 4.6 1 PMID:25819959 -1.13.11.85 * xanthomonas sp. 35y 2.6 2.25 2 PMID:28500046 -1.13.11.87 * gordonia polyisoprenivorans 4.66 3.25 3 PMID:32439426 -1.13.11.87 * nocardia nova 0.03 0.03 1 PMID:31308317 -1.13.11.87 * piscinibacter gummiphilus 4.8 4.8 1 PMID:30215127 -1.13.11.87 * rhodococcus rhodochrous 3.1 2.0 2 PMID:27215318 -1.13.11.87 * streptomyces sp. k30 4.6 3.05 2 PMID:25819959 -1.13.11.87 * xanthomonas sp. 35y 6.4 5.7 3 PMID:28500046 -1.13.11.88 * pseudomonas nitroreducens 4.2 4.2 1 PMID:23391906 -1.13.11.88 * pseudomonas putida 5.53 5.53 1 PMID:17516050 -1.13.11.88 * pseudomonas sp. 4.6 4.6 1 * -1.13.11.9 * achromobacter sp. 15.3 15.3 1 PMID:4455192 -1.13.11.9 * cupriavidus campinensis 0.13 0.13 1 * -1.13.11.9 * pseudomonas putida 38.3 6.0 3 PMID:18678916;PMID:5578917 -1.13.11.91 * cupriavidus necator 2.2 2.2 1 PMID:26590284 -1.13.11.92 * arabidopsis thaliana 11.0 11.0 1 PMID:15100225 -1.13.11.92 * lathyrus oleraceus 2.94 2.94 1 PMID:10938370 -1.13.12.1 * arthrobacter globiformis 0.02 0.02 1 * -1.13.12.1 * brevibacterium helvolum 0.07 0.07 1 * -1.13.12.1 * brevibacterium lipolyticum 0.0004 0.0004 1 * -1.13.12.1 * pimelobacter simplex 0.05 0.05 1 * -1.13.12.16 * cyberlindnera mrakii 397.0 397.0 3 PMID:947888 -1.13.12.16 * fusarium oxysporum 0.46 0.46 1 PMID:22538 -1.13.12.16 * neurospora crassa 10000.0 80.0 6 PMID:15582992;PMID:9501443 -1.13.12.19 * pseudomonas syringae 660.0 660.0 1 PMID:1770346 -1.13.12.2 * pseudomonas fluorescens 10.3 10.3 1 PMID:5911646 -1.13.12.2 * pseudomonas putida 6.1 6.1 1 PMID:25012259 -1.13.12.2 * pseudomonas sp. aiu 813 0.532 0.146 3 PMID:24693490 -1.13.12.21 * streptomyces glaucescens 0.599 0.599 1 PMID:8329392 -1.13.12.3 * pseudomonas savastanoi 13.28 12.7 3 PMID:3997822;PMID:5916389;PMID:7840624 -1.13.12.4 * mycolicibacterium phlei 32.0 17.325 2 PMID:7236621 -1.13.12.4 * mycolicibacterium smegmatis 53.6 33.55 2 PMID:1191251;PMID:6849875;PMID:921754 -1.13.12.9 * pseudomonas sp. 102.5 102.5 1 PMID:7174643 -1.13.99.1 * arabidopsis thaliana 4.9 3.535 2 PMID:14976233;PMID:31088620 -1.13.99.1 * mus musculus 5.0 0.035 10 PMID:19060162;PMID:31088620 -1.13.99.1 * thermothelomyces thermophilus 5.1 5.1 1 PMID:31088620 -1.13.99.3 * pseudomonas fluorescens 29.2 29.2 1 PMID:500674 -1.13.99.3 * pseudomonas sp. 14.0 7.65 2 PMID:15994 -1.14.11.1 * bos taurus 0.053 0.053 1 PMID:6798936 -1.14.11.1 * homo sapiens 1.02 0.591 2 PMID:6497835;PMID:7126226 -1.14.11.1 * pseudomonas sp. 25.0 23.3 2 PMID:1988434;PMID:861203 -1.14.11.1 * rattus norvegicus 0.0274 0.003 3 PMID:3571282;PMID:4382529;PMID:4396068 -1.14.11.1 * sus scrofa 0.0024 7e-05 9 PMID:19285565;PMID:19523885 -1.14.11.10 * rhodotorula glutinis 5.0 5.0 1 PMID:4040518 -1.14.11.12 * spinacia oleracea 0.003 0.003 1 PMID:16665690 -1.14.11.15 * arabidopsis thaliana 0.259 0.1403 2 PMID:16181493 -1.14.11.15 * cucurbita maxima 0.065 0.065 1 * -1.14.11.16 * bos taurus 14.0 7.295 2 PMID:1856229;PMID:8041771 -1.14.11.17 * escherichia coli 3.56 1.64 3 PMID:22221834;PMID:9287300 -1.14.11.17 * pseudomonas putida 8.11 8.11 1 PMID:22221834 -1.14.11.18 * homo sapiens 4.1e-05 2.65e-06 4 PMID:10709665;PMID:10866807;PMID:8954107;PMID:9565335 -1.14.11.18 * mus musculus 1.8e-06 1.8e-06 1 PMID:10866807 -1.14.11.18 * platyrrhini 1e-06 1e-06 1 PMID:10866807 -1.14.11.18 * rattus norvegicus 0.00026 0.0001 3 PMID:10588950;PMID:10866807;PMID:7556205 -1.14.11.2 * chlamydomonas reinhardtii 0.000786 0.000426 2 PMID:24232556 -1.14.11.2 * gallus gallus 2.4 0.7050000000000001 8 PMID:170085;PMID:6210830;PMID:6255999;PMID:6285984 -1.14.11.2 * glarea lozoyensis 231.0 231.0 1 PMID:12883873 -1.14.11.2 * homo sapiens 2300.0 39.55 4 PMID:15555944;PMID:170109;PMID:6210830 -1.14.11.2 * mytilus edulis 0.052 0.02681 2 PMID:2832510 -1.14.11.2 * phaseolus vulgaris 87.53 0.45 8 PMID:2996486 -1.14.11.2 * rattus norvegicus 1.3 1.2974999999999999 2 PMID:186037;PMID:6210830 -1.14.11.20 * catharanthus roseus 0.00517 0.00105 16 PMID:18587132;PMID:8449913 -1.14.11.21 * streptomyces antibioticus 0.1 0.1 1 PMID:7890654 -1.14.11.21 * streptomyces clavuligerus 0.86 0.685 4 PMID:2207091;PMID:7876185;PMID:8229018 -1.14.11.26 * hapsidospora chrysogena 0.127 0.127 1 PMID:3558321 -1.14.11.28 * bacillus sp. (in: firmicutes) 0.00149 0.001405 2 PMID:16535329 -1.14.11.28 * streptomyces canus 0.00029 0.00029 1 PMID:16535329 -1.14.11.28 * streptomyces sp. 12.7 7.2 3 PMID:16535329 -1.14.11.3 * neurospora crassa 0.053 0.053 1 PMID:4260374 -1.14.11.3 * rhodotorula glutinis 0.97 0.6599999999999999 2 PMID:4040518;PMID:6684117 -1.14.11.45 * bacillus subtilis 3.8 3.8 1 PMID:33249835 -1.14.11.55 * streptomyces coelicolor 20.0 20.0 1 PMID:18849444 -1.14.11.55 * virgibacillus salexigens 3.06 3.06 1 PMID:17636255 -1.14.11.56 * mesorhizobium loti 684.0 0.34 3 PMID:19133227;PMID:25171735 -1.14.11.56 * sinorhizobium meliloti 707.0 707.0 1 PMID:19133227 -1.14.11.57 * dactylosporangium sp. rh1 2080.0 2080.0 1 PMID:10473412 -1.14.11.57 * streptomyces griseoviridis 907.0 907.0 1 * -1.14.11.6 * neurospora crassa 0.042 0.042 1 * -1.14.11.6 * rhodotorula glutinis 30.0 23.05 2 PMID:6684117;PMID:8268182 -1.14.11.64 * escherichia coli 0.053 0.053 1 PMID:30498244 -1.14.11.66 * homo sapiens 0.0035 0.001755 24 PMID:19799855 -1.14.11.8 * rattus norvegicus 0.0586 0.0586 1 PMID:11431483 -1.14.11.9 * arabidopsis thaliana 25.0 25.0 1 PMID:18657430 -1.14.11.9 * camellia sinensis 0.032 0.032 1 PMID:18595847 -1.14.11.9 * prunus avium 5.6e-05 4.05e-05 4 PMID:19435288 -1.14.11.9 * prunus cerasus 0.00094 0.0009 3 PMID:19435288 -1.14.11.9 * prunus domestica 5e-05 3.45e-05 2 PMID:19435288 -1.14.11.9 * ribes uva-crispa 0.00012 3.7000000000000005e-05 4 PMID:19435288 -1.14.11.9 * rubus fruticosus 2.7e-05 2.3e-05 5 PMID:19435288 -1.14.11.9 * rubus idaeus 9.2e-05 7.9e-05 2 PMID:19435288 -1.14.11.9 * sambucus nigra 4.1e-05 2.8e-05 7 PMID:19435288 -1.14.12.10 * acinetobacter calcoaceticus 5.0 5.0 1 PMID:12949084 -1.14.12.10 * pseudomonas putida 790.0 4.9 3 PMID:12135383;PMID:7372624 -1.14.12.11 * pseudomonas putida 2.58 0.055 6 PMID:15746362;PMID:526270;PMID:8787410;PMID:9872799 -1.14.12.12 * corynebacterium renale 1.05 1.05 1 PMID:7333274 -1.14.12.12 * pseudomonas aeruginosa 139.33 54.900000000000006 6 PMID:33025721 -1.14.12.12 * pseudomonas sp. 397.0 199.185 2 PMID:2294092;PMID:6874638 -1.14.12.12 * rhodococcus sp. (in: high g+c gram-positive bacteria) 0.006 0.006 1 PMID:10498739 -1.14.12.13 * burkholderia cepacia 4.0 0.28650000000000003 4 PMID:1370284;PMID:2610934 -1.14.12.13 * burkholderia sp. 0.458 0.032 9 PMID:11160806;PMID:11179677 -1.14.12.13 * pseudomonas aeruginosa 1.57 1.57 1 PMID:8195093 -1.14.12.13 * pseudomonas sp. 0.018 0.018 1 PMID:8934785 -1.14.12.15 * delftia tsuruhatensis 2.8 2.8 1 PMID:12670689 -1.14.12.16 * comamonas testosteroni 0.125 0.125 1 PMID:7556204 -1.14.12.17 * escherichia coli 0.2095 0.015 3 PMID:9724711;PMID:9756889 -1.14.12.18 * comamonas testosteroni 4.9 4.9 1 PMID:10777527 -1.14.12.18 * pseudomonas sp. 0.15 0.15 1 PMID:8002618 -1.14.12.18 * sphingobium yanoikuyae 217.0 122.95 2 PMID:17211635 -1.14.12.24 * burkholderia sp. 385.0 19.0 5 PMID:12743828;PMID:9573183 -1.14.12.3 * pseudomonas putida 0.115 0.0204 8 PMID:11525620;PMID:15746362 -1.14.12.7 * burkholderia cepacia 1.31 1.31 1 PMID:2280719 -1.14.12.8 * comamonas testosteroni 318.0 0.455 8 PMID:2012609;PMID:8828208 -1.14.12.9 * pseudomonas sp. 30.0 15.072 2 PMID:3036855;PMID:3745216 -1.14.13.1 * alcaligenes sp. 0.0127 0.0072 2 PMID:20727010 -1.14.13.1 * cutaneotrichosporon cutaneum 37.0 37.0 1 PMID:6539772 -1.14.13.1 * pseudomonas fluorescens 7.55 7.55 1 PMID:26027357 -1.14.13.1 * pseudomonas putida 5.0 2.815 2 PMID:11826899;PMID:26027357 -1.14.13.1 * pseudomonas reinekei 460.0 120.0 7 PMID:14617643;PMID:17172348 -1.14.13.1 * pseudomonas sp. 25.64 4.12 17 PMID:14321380;PMID:15240281;PMID:16035243;PMID:4401700;PMID:713855 -1.14.13.10 * paenarthrobacter nicotinovorans 90.0 46.08 2 PMID:11514508;PMID:4344227 -1.14.13.101 * apantesis nevadensis geneura 3.3 3.3 1 PMID:20454663 -1.14.13.101 * tyria jacobaeae 4.67 4.67 1 PMID:9182998 -1.14.13.111 * afipia felis 31.0 27.0 2 PMID:15643932 -1.14.13.111 * methylosulfonomonas methylovora 0.88 0.88 1 PMID:10903510 -1.14.13.114 * pseudomonas fluorescens 6.67 6.67 1 PMID:10091591 -1.14.13.127 * escherichia coli 0.94 0.7749999999999999 2 PMID:31811039 -1.14.13.128 * pseudomonas putida 55.4 55.4 1 PMID:20966097 -1.14.13.130 * rhodococcus sp. (in: high g+c gram-positive bacteria) 1.82 1.82 1 PMID:9395321 -1.14.13.131 * hyphomicrobium sulfonivorans 1.256 1.256 1 PMID:21216999 -1.14.13.135 * alcaligenes sp. 25.3 0.0877 3 PMID:20727010 -1.14.13.14 * melilotus albus 0.0004 0.0004 1 PMID:4153528 -1.14.13.148 * calanus finmarchicus 0.085 0.042735 2 * -1.14.13.148 * homo sapiens 0.201 0.125 2 PMID:9224773 -1.14.13.148 * oryctolagus cuniculus 0.025 0.025 1 PMID:8188717 -1.14.13.16 * pseudomonas sp. 4.3 4.3 1 PMID:2177830;PMID:4313 -1.14.13.160 * pseudomonas putida 2200.0 1101.34 2 PMID:22286514;PMID:6848481 -1.14.13.163 * agrobacterium tumefaciens 18.8 14.55 2 PMID:25054198 -1.14.13.163 * pseudomonas putida 4.8 4.8 1 PMID:21949128 -1.14.13.163 * pseudomonas sp. zz-5 31.8 18.45 2 * -1.14.13.166 * lysinibacillus sphaericus 0.04 0.01965 4 PMID:9647818 -1.14.13.166 * pseudomonas sp. 1.9 1.9 1 PMID:19218392 -1.14.13.167 * burkholderia sp. 7.2 5.199999999999999 4 PMID:25085488 -1.14.13.167 * pseudomonas sp. 6.8 3.6 2 PMID:19218392 -1.14.13.167 * rhodococcus opacus 2.64e-05 2.5e-05 3 PMID:15262926 -1.14.13.172 * ralstonia sp. 107.1 53.5755 2 PMID:11872705;PMID:23624660 -1.14.13.18 * delftia acidovorans 2.2 2.2 1 PMID:234937 -1.14.13.181 * streptomyces sp. 0.0006 0.0006 1 PMID:9864343 -1.14.13.195 * pseudomonas aeruginosa 0.534 0.321 3 PMID:17015659;PMID:17900176 -1.14.13.2 * acinetobacter calcoaceticus 38.0 38.0 1 PMID:7490269 -1.14.13.2 * alcaligenes sp. pph 0.016 0.016 1 PMID:17169001 -1.14.13.2 * klebsiella pneumoniae 5.76 5.76 1 PMID:7646318 -1.14.13.2 * moraxella sp. 10.2 10.2 1 * -1.14.13.2 * pseudomonas aeruginosa 16.85 16.85 1 PMID:28650068 -1.14.13.2 * pseudomonas fluorescens 52.2 47.5 3 PMID:116851;PMID:30879;PMID:4402514 -1.14.13.2 * pseudomonas sp. ppd 0.281 0.281 1 PMID:17169001 -1.14.13.2 * rhodococcus rhodnii 25.0 25.0 1 PMID:11566060 -1.14.13.20 * acinetobacter sp. 1.46 1.46 1 PMID:7075592 -1.14.13.20 * burkholderia cepacia 1.9 1.9 1 PMID:1898014 -1.14.13.20 * cupriavidus necator 1.48 1.31 2 PMID:6745439;PMID:9090109 -1.14.13.20 * pseudomonadota 2.4 2.1 2 PMID:9418244 -1.14.13.200 * streptomyces glaucescens 0.00429 0.00429 1 PMID:7982994 -1.14.13.210 * pseudomonas sp. 0.03 0.03 1 PMID:8195105 -1.14.13.212 * pseudomonas sp. 4.128 4.128 1 PMID:22609920 -1.14.13.22 * acinetobacter calcoaceticus 9.2 4.8 4 PMID:19397940 -1.14.13.22 * acinetobacter sp. 21.0 15.0 7 PMID:11162390;PMID:1261545;PMID:14597129;PMID:2177829;PMID:2540966 -1.14.13.22 * arthrobacter sp. 24.75 14.16 2 PMID:12514013 -1.14.13.22 * exophiala jeanselmei 678.0 678.0 1 PMID:11210139 -1.14.13.22 * ilyonectria destructans 6.8 6.8 1 PMID:22075635 -1.14.13.22 * nocardia globerula 9.9 9.9 1 PMID:1261545 -1.14.13.22 * rhodococcus pyridinivorans 3.68 3.68 1 PMID:12514013 -1.14.13.22 * rhodococcus ruber 3.75 3.75 1 PMID:12514013 -1.14.13.22 * rhodococcus sp. hi-31 6.0 6.0 1 PMID:19385644 -1.14.13.22 * xanthobacter sp. 2.1 2.1 1 PMID:2177829;PMID:2540966 -1.14.13.23 * bacillus sp. (in: firmicutes) 0.01 0.01 1 PMID:8754626 -1.14.13.23 * comamonas testosteroni 11.8 5.17 5 PMID:17046018;PMID:4148586 -1.14.13.236 * burkholderia cepacia 1.6 1.05 2 PMID:18192418 -1.14.13.236 * ectopseudomonas mendocina 23890.0 625.8 4 PMID:11035951;PMID:18192418;PMID:8703915 -1.14.13.24 * aquipseudomonas alcaligenes 1.63 1.63 1 PMID:16267294 -1.14.13.24 * burkholderia cepacia 23.7 23.7 1 PMID:3567157 -1.14.13.24 * corynebacterium glutamicum 6.92 6.92 1 PMID:20806251 -1.14.13.24 * klebsiella oxytoca 0.53 0.53 1 PMID:15782938 -1.14.13.24 * klebsiella pneumoniae 8.42 8.42 1 PMID:7729672 -1.14.13.24 * martelella sp. ad-3 25.2 25.2 1 PMID:30034371 -1.14.13.24 * micrococcus sp. 21.4 21.4 1 PMID:2321959 -1.14.13.24 * pseudomonas aeruginosa 24.0 24.0 1 PMID:4357436 -1.14.13.24 * rhodococcus jostii 24.0 15.0 2 PMID:22207056 -1.14.13.24 * rhodococcus sp. (in: high g+c gram-positive bacteria) 5.8 5.8 1 PMID:21181154 -1.14.13.241 * pseudomonas sp. 8.5 8.5 1 PMID:3771566 -1.14.13.242 * mesorhizobium loti 3.28 3.28 1 PMID:17270714 -1.14.13.242 * pseudomonas sp. 4.03 4.03 1 PMID:9054568 -1.14.13.25 * methylobacterium sp. 0.208 0.208 1 PMID:3106336 -1.14.13.25 * methylococcus capsulatus 11.37 2.695 10 PMID:10381404;PMID:15898785;PMID:20681546;PMID:220953;PMID:3933977;PMID:3934164;PMID:418777;PMID:6323414 -1.14.13.25 * methylocystis sp. 0.334 0.0191 9 PMID:10473397 -1.14.13.25 * methylosinus sporium 494.0 17.5 3 * -1.14.13.25 * methylosinus trichosporium 26.1 0.604 7 PMID:15544;PMID:17213640;PMID:18540635;PMID:2280705;PMID:2542319;PMID:2840063 -1.14.13.25 * paraburkholderia terrae 5.37 5.37 1 PMID:34965585 -1.14.13.252 * shewanella putrefaciens 0.447 0.35950000000000004 2 PMID:30654014 -1.14.13.27 * agaricus bisporus 28.0 0.91 3 PMID:10423528;PMID:3875343 -1.14.13.29 * mus musculus 0.00411 0.00343 2 PMID:19501084 -1.14.13.29 * ovis aries 0.000494 0.000494 1 PMID:2126753 -1.14.13.29 * rattus norvegicus 3.7e-05 3.7e-05 1 PMID:11850968 -1.14.13.29 * rhodococcus opacus 34.2 6.417000000000001 6 PMID:34469195 -1.14.13.29 * rhodococcus sp. pn1 24.5 17.85 2 PMID:18805976 -1.14.13.29 * sus scrofa 161.5 132.8 3 PMID:22444842 -1.14.13.31 * lysinibacillus sphaericus 0.04 0.04 1 PMID:9647818 -1.14.13.31 * pseudomonas putida 60.0 31.0 4 PMID:3350791;PMID:3752997 -1.14.13.32 * dicrocoelium dendriticum 5.2e-05 3.785e-05 2 PMID:18565554 -1.14.13.32 * rattus norvegicus 0.013 0.006795 2 PMID:3739217;PMID:7736906 -1.14.13.33 * burkholderia cepacia 0.12 0.12 1 * -1.14.13.33 * paenibacillus sp. 0.47 0.415 2 PMID:19717587 -1.14.13.33 * sinomonas cyclohexanicum 30.5 30.5 1 PMID:3971979 -1.14.13.35 * aspergillus niger 25.8 0.23650000000000002 14 PMID:2310183;PMID:4389022;PMID:4632396;PMID:5563863;PMID:6501219 -1.14.13.35 * cutaneotrichosporon cutaneum 4.4 1.02 3 PMID:3793735;PMID:7194334 -1.14.13.38 * kitasatospora aureofaciens 0.44 0.0078 3 PMID:3121478;PMID:3138982 -1.14.13.38 * streptomyces rimosus 1.12e-05 1.12e-05 1 PMID:16148009 -1.14.13.39 * bos taurus 0.41 0.2415 4 PMID:1371919;PMID:9701047;PMID:9875419 -1.14.13.39 * homo sapiens 38.0 0.19 7 PMID:10608822;PMID:11125020;PMID:12586536;PMID:1377649;PMID:1722402;PMID:9224737 -1.14.13.39 * mus musculus 1.62 0.031 13 PMID:11744335;PMID:1379468;PMID:1715579;PMID:1720773;PMID:7530045;PMID:7691806;PMID:9799513 -1.14.13.39 * nicotiana tabacum 983.7 983.7 1 PMID:12757708 -1.14.13.39 * ovis aries 0.6 0.6 1 * -1.14.13.39 * rattus norvegicus 1.9 0.0649 10 PMID:11742852;PMID:1372827;PMID:1378272;PMID:1379222;PMID:1695842;PMID:1700708;PMID:1704888;PMID:1712021;PMID:7521166 -1.14.13.39 * staphylococcus aureus 0.0353 0.0353 1 PMID:12770704 -1.14.13.39 * sus scrofa 0.73 0.37 2 PMID:1375940;PMID:1702732 -1.14.13.39 * triatoma infestans 0.0075 0.0075 1 PMID:17235602 -1.14.13.4 * arthrobacter sp. 12.5 12.5 1 PMID:6017743 -1.14.13.4 * pseudomonas sp. 35.3 35.3 1 PMID:4348920 -1.14.13.40 * pseudomonas sp. 25.0 12.5075 2 PMID:1592816;PMID:2591379 -1.14.13.46 * rattus sp. 0.002 0.002 1 PMID:2906604 -1.14.13.5 * pseudomonas sp. 25.0 25.0 1 PMID:5772468 -1.14.13.50 * pseudomonas fluorescens 3.7 3.7 1 PMID:12783196 -1.14.13.51 * rhodococcus 0.3 0.1505 2 * -1.14.13.54 * rhodococcus rhodochrous 0.95 0.95 1 PMID:10467180 -1.14.13.58 * pseudomonas sp. 1.812 0.9185 2 PMID:7851381;PMID:8335640 -1.14.13.59 * escherichia coli 0.444 0.238 5 PMID:10064136;PMID:2518519;PMID:8218389 -1.14.13.6 * pseudomonas putida 37.0 13.8 8 PMID:1126936;PMID:11945483;PMID:1280;PMID:220242 -1.14.13.61 * pseudomonas putida 32.5 16.735 2 PMID:7629085 -1.14.13.62 * pseudomonas putida 6.8 6.8 1 PMID:1627263 -1.14.13.63 * flavobacterium sp. 20.1 20.1 1 PMID:1935954 -1.14.13.63 * rhodococcus erythropolis 2544.0 2544.0 1 * -1.14.13.64 * candida parapsilosis 14.0 13.0 2 PMID:33684360;PMID:9352916 -1.14.13.69 * gordonia rubripertincta 0.085 0.085 1 PMID:9266707 -1.14.13.69 * rhodococcus rhodochrous 0.145 0.145 1 PMID:15943801 -1.14.13.69 * rhodococcus sp. ad45 0.0041 0.0041 1 PMID:35285709 -1.14.13.7 * acinetobacter radioresistens 429.5 429.5 1 PMID:10504385 -1.14.13.7 * auxenochlorella pyrenoidosa 0.39 0.39 1 PMID:28662620 -1.14.13.7 * candida albicans 0.087 0.08499999999999999 2 PMID:16377894 -1.14.13.7 * cutaneotrichosporon cutaneum 8.3 5.0 11 PMID:3319618;PMID:4146224;PMID:6838815;PMID:7851397;PMID:7858421;PMID:8269923 -1.14.13.7 * pseudomonas sp. 0.78 0.78 1 PMID:12186554 -1.14.13.7 * trametes versicolor 0.333 0.333 1 PMID:18712560 -1.14.13.8 * bos taurus 0.00375 0.00373 3 * -1.14.13.8 * canis lupus familiaris 3.67e-05 2.65e-05 2 PMID:19635782 -1.14.13.8 * cavia porcellus 0.436 0.423 2 PMID:2369122 -1.14.13.8 * mus musculus 2.4 0.069 9 PMID:17721934;PMID:3919719 -1.14.13.8 * oryctolagus cuniculus 0.52 0.52 1 PMID:3919719 -1.14.13.8 * ovis aries 0.0123 0.0084 4 PMID:15473006 -1.14.13.8 * rattus norvegicus 0.15 0.15 1 PMID:18775983 -1.14.13.8 * sus scrofa 6.2 0.176 5 PMID:15193961;PMID:672624;PMID:7758472 -1.14.13.81 * hordeum vulgare 8.5e-06 8.5e-06 1 PMID:15824317 -1.14.13.82 * pseudomonas putida 0.003 0.003 1 PMID:16242864 -1.14.13.83 * pseudomonas denitrificans (nom. rej.) 0.048 0.048 1 PMID:8226690 -1.14.13.84 * pseudomonas fluorescens 5.5 5.5 1 PMID:11322873 -1.14.13.84 * pseudomonas putida 23.2 7.8 4 PMID:11073896;PMID:19251889 -1.14.13.9 * anopheles stephensi 0.866 0.4805 2 PMID:12230548 -1.14.13.9 * cavia porcellus 0.0015 0.0015 1 PMID:15206763 -1.14.13.9 * mus musculus 0.004 0.0032500000000000003 2 PMID:15206763 -1.14.13.9 * oryctolagus cuniculus 0.001 0.00075 4 PMID:15206763;PMID:16126232 -1.14.13.9 * pseudomonas fluorescens 3.15 3.15 1 PMID:16973376 -1.14.13.9 * rattus norvegicus 47.0 0.050499999999999996 8 PMID:10672018;PMID:1225915;PMID:15206763;PMID:15970278;PMID:536427;PMID:6076241 -1.14.14.1 * apium graveolens 0.083 0.031 13 PMID:19768461 -1.14.14.1 * cyprinus carpio 1.5e-07 6.6e-08 3 PMID:16715285 -1.14.14.1 * hypophthalmichthys molitrix 0.0002166 1.32e-06 6 PMID:16715285 -1.14.14.1 * rheum rhaponticum 0.038 0.0288 13 PMID:19768461 -1.14.14.1 * silurus glanis 3.25e-05 1.9235e-06 6 PMID:16715285 -1.14.14.1 * streptomyces tubercidicus 0.001 0.001 1 PMID:16269732 -1.14.14.1 * zea mays 0.139 0.053000000000000005 14 PMID:19768461 -1.14.14.10 * aminobacter aminovorans 0.076 0.076 1 PMID:8892809 -1.14.14.108 * pseudomonas putida 420.0 6.78 10 PMID:13880914;PMID:3944058;PMID:4286778;PMID:4288652;PMID:4310834;PMID:8515237 -1.14.14.109 * zea mays 0.0002 0.0002 1 PMID:10385992 -1.14.14.11 * pseudomonas sp. 2.1 2.0 2 PMID:15292130 -1.14.14.11 * rhodococcus opacus 0.12 0.087 3 PMID:26054733 -1.14.14.11 * rhodococcus sp. (in: high g+c gram-positive bacteria) 0.0304 0.01845 4 PMID:22258641 -1.14.14.110 * zea mays 0.00016 0.00016 1 PMID:10385992 -1.14.14.112 * oryza sativa 0.13 0.13 1 PMID:19825834 -1.14.14.117 * aspergillus parasiticus 34.11 17.169999999999998 2 PMID:1902378 -1.14.14.139 * oryctolagus cuniculus 0.484 0.484 1 PMID:1400444 -1.14.14.139 * rattus norvegicus 0.000885 0.000885 1 PMID:3939046 -1.14.14.14 * homo sapiens 57.0 57.0 1 PMID:3104339 -1.14.14.153 * zea mays 0.00033 0.00033 1 PMID:10385992 -1.14.14.154 * bos taurus 0.00756 0.00756 1 PMID:18466759 -1.14.14.154 * rattus norvegicus 8.4e-06 8.4e-06 1 PMID:8982866 -1.14.14.155 * pseudomonas putida 300.0 0.352 4 PMID:22286514;PMID:8515237 -1.14.14.157 * zea mays 0.00194 0.00194 1 PMID:10385992 -1.14.14.16 * bos taurus 0.0452 0.0077 7 PMID:3931675;PMID:6972231;PMID:7130172 -1.14.14.16 * homo sapiens 0.00122 0.0011949999999999999 2 PMID:15126570 -1.14.14.17 * rattus norvegicus 0.17 0.00619 3 PMID:3927114;PMID:6776955;PMID:6817796;PMID:7595073 -1.14.14.17 * saccharomyces cerevisiae 0.0001 6.605e-05 2 PMID:3307781;PMID:8358382 -1.14.14.17 * trichophyton rubrum 1.2e-05 1.2e-05 1 PMID:8834895 -1.14.14.173 * cupriavidus necator 0.327 0.16525 2 PMID:12057943 -1.14.14.173 * cupriavidus sp. gp1 6.87 3.525 2 PMID:8981999 -1.14.14.18 * bos taurus 0.113 0.05673 2 PMID:3120697;PMID:6806282 -1.14.14.18 * gallus gallus 0.433 0.433 1 PMID:2158889 -1.14.14.18 * glycine max 0.641 0.10849999999999999 4 PMID:15381099 -1.14.14.18 * homo sapiens 0.0705 0.0205 4 PMID:17915953;PMID:3202858;PMID:7703255;PMID:7890772 -1.14.14.18 * oryctolagus cuniculus 0.138 0.0722 2 PMID:2910857 -1.14.14.18 * rattus norvegicus 12.7 0.08499999999999999 12 PMID:17253780;PMID:18208506;PMID:18477;PMID:22882835;PMID:2910857;PMID:3525562;PMID:438202;PMID:6809753 -1.14.14.18 * sus scrofa 0.000175 0.000175 1 PMID:96115 -1.14.14.19 * bos taurus 0.47 0.375 2 PMID:17786622 -1.14.14.19 * cavia porcellus 0.1 0.079 2 PMID:17786622 -1.14.14.19 * sus scrofa 0.125 0.0615 4 PMID:17786622;PMID:6971291 -1.14.14.197 * aspergillus ochraceus 0.388 0.2182 2 PMID:6810893 -1.14.14.20 * parageobacillus thermoglucosidasius 802.0 0.32 4 PMID:12968028 -1.14.14.20 * rhodococcus erythropolis 411.7 226.7 2 PMID:19787347 -1.14.14.21 * bacillus subtilis 163.2 123.69999999999999 2 PMID:16243275 -1.14.14.21 * paenibacillus sp. 18.6 18.6 1 PMID:12382053 -1.14.14.21 * rhodococcus erythropolis 133.0 133.0 1 PMID:11105249 -1.14.14.21 * rhodococcus sp. (in: high g+c gram-positive bacteria) 3.0 3.0 1 PMID:17581702 -1.14.14.22 * bacillus subtilis 875.0 865.0 2 PMID:16243275 -1.14.14.22 * paenibacillus sp. 77.2 33.400000000000006 8 PMID:16232919 -1.14.14.22 * rhodococcus erythropolis 807.0 807.0 1 PMID:11105249;PMID:16232672 -1.14.14.23 * homo sapiens 0.00294 0.00045999999999999996 6 PMID:15752749;PMID:2106520;PMID:8938182 -1.14.14.23 * rattus norvegicus 156.0 0.00076 14 PMID:11209749;PMID:16081591;PMID:2106520;PMID:2154492;PMID:3584134;PMID:8938182 -1.14.14.24 * rattus norvegicus 6400.0 6400.0 1 PMID:15026419 -1.14.14.27 * pseudomonas putida 11.6 11.6 1 PMID:1280 -1.14.14.3 * vibrio harveyi 0.105 0.105 1 PMID:12525181 -1.14.14.30 * streptomyces viridifaciens 51.1 51.1 1 PMID:8990292 -1.14.14.32 * homo sapiens 3.75e-05 3.75e-05 1 PMID:23415678 -1.14.14.32 * sus scrofa 7.3e-06 7.3e-06 1 PMID:23415678 -1.14.14.33 * chelativorans multitrophicus 107.0 30.0 5 PMID:9371437 -1.14.14.33 * chelativorans oligotrophicus 156.0 81.0 3 * -1.14.14.33 * edta-degrading bacterium bnc1 3.8 3.8 1 * -1.14.14.33 * stenotrophomonas chelatiphaga 29.0 17.0 3 * -1.14.14.34 * pseudomonas putida 121000.0 101950.0 2 PMID:12835925 -1.14.14.36 * sorghum bicolor 49.2 24.61165 2 PMID:7574710 -1.14.14.37 * sorghum bicolor 0.003 0.003 1 PMID:237909 -1.14.14.47 * nocardia sp. 318.0 318.0 1 PMID:7522444 -1.14.14.5 * escherichia coli 2.5 2.5 1 PMID:10480865 -1.14.14.51 * mentha spicata 0.0007 0.0006900000000000001 2 PMID:1595887;PMID:2297225 -1.14.14.52 * perilla frutescens 0.0001567 0.0001567 1 PMID:2297225 -1.14.14.8 * geobacillus thermodenitrificans 151.3 151.3 1 PMID:19942660 -1.14.14.80 * homo sapiens 24.5 10.25 8 PMID:7798189 -1.14.14.81 * osteospermum hybrid cultivar 2.6e-06 2.6e-06 1 PMID:17612530 -1.14.14.82 * gerbera hybrid cultivar 3e-06 3e-06 1 PMID:17612530 -1.14.14.83 * catharanthus roseus 8.66 8.66 1 * -1.14.14.84 * pseudomonas putida 0.014 0.0091 2 PMID:2295633 -1.14.14.85 * lonicera japonica 9.9e-05 9.9e-05 1 PMID:11524113 -1.14.14.9 * acinetobacter baumannii 201.0 104.445 6 PMID:11683878;PMID:15451173 -1.14.14.9 * escherichia coli 3.4 0.191 7 PMID:10633095;PMID:10653707;PMID:12809507;PMID:6995433 -1.14.14.9 * pseudomonas putida 197.3 101.9 2 PMID:3401220 -1.14.14.9 * sulfobacillus acidophilus 27.37 27.37 1 PMID:30760216 -1.14.14.92 * aspergillus niger 0.26 0.1744 2 PMID:236777 -1.14.14.92 * pseudomonas sp. 33.92 33.92 1 PMID:13716 -1.14.14.92 * rhodotorula graminis 0.041 0.041 1 PMID:6389497 -1.14.14.93 * glycine max 0.00054 0.00030000000000000003 2 PMID:3963819 -1.14.14.94 * homo sapiens 30.0 15.077 2 PMID:3070301;PMID:9675028 -1.14.14.97 * corydalis vaginans 0.0255 0.0255 1 * -1.14.14.99 * mentha x piperita 0.000685 0.00050915 2 PMID:1595887;PMID:2297225 -1.14.15.1 * pseudomonas putida 30.26 30.26 1 PMID:672627 -1.14.15.1 * pseudomonas sp. 0.016 0.016 1 PMID:4378858 -1.14.15.15 * homo sapiens 0.672 0.672 1 PMID:6338006 -1.14.15.15 * rattus norvegicus 0.431 0.114 3 PMID:1880123;PMID:2848026 -1.14.15.18 * bos taurus 8.2e-06 8.2e-06 1 PMID:6807301 -1.14.15.18 * gallus gallus 11.38 0.602 7 PMID:219848;PMID:4404596;PMID:6767897;PMID:816255;PMID:819434 -1.14.15.18 * homo sapiens 1.5e-06 4.2e-07 5 PMID:10518789;PMID:11686044;PMID:1499638 -1.14.15.18 * mus musculus 4.3e-06 1.3e-06 4 PMID:10092858;PMID:11686044 -1.14.15.18 * rattus norvegicus 0.0048 0.0048 1 PMID:9426217 -1.14.15.18 * sus scrofa 7.2e-06 7.2e-06 1 PMID:2719667 -1.14.15.20 * cyanidium caldarium 0.1403 0.070495 2 PMID:7793979 -1.14.15.24 * agrobacterium aurantiacum 1000000.0 575000.0 2 PMID:9045623 -1.14.15.24 * alcaligenes sp. 467000.0 262000.0 2 PMID:9045623 -1.14.15.24 * pantoea ananatis 617000.0 358500.0 2 PMID:9045623 -1.14.15.3 * corynebacterium sp. 4.26 4.26 1 PMID:4317878 -1.14.15.3 * ectopseudomonas oleovorans 596.0 1.875 6 PMID:12804773;PMID:4395379;PMID:4830742;PMID:713843;PMID:921275 -1.14.15.3 * fusarium oxysporum 6.5 6.5 1 PMID:8830036 -1.14.15.3 * penicillium chrysogenum 351.32 351.32 1 PMID:35239044 -1.14.15.3 * pseudomonas putida 0.00773 0.005415 4 PMID:15294784 -1.14.15.30 * mycolicibacterium neoaurum 0.98 0.14 24 PMID:27516945;PMID:29728384 -1.14.15.4 * bos taurus 1.38 0.002415 10 PMID:3485096;PMID:412519;PMID:6978716;PMID:889836 -1.14.15.4 * homo sapiens 0.0198 0.0198 1 PMID:18215163 -1.14.15.4 * rattus norvegicus 0.01633 0.00821 12 PMID:2789017;PMID:9057984 -1.14.15.7 * amaranthus caudatus 0.0001 6.8e-05 2 PMID:9489025 -1.14.15.7 * beta vulgaris 0.00048 0.00018 5 PMID:9489025 -1.14.15.7 * spinacia oleracea 0.00058 0.000415 2 PMID:16666757 -1.14.15.8 * priestia megaterium 0.0008 0.0008 1 PMID:109432 -1.14.16.1 * apodemus sylvaticus 0.006 0.0034850000000000003 2 PMID:10909822 -1.14.16.1 * bos taurus 0.23 0.17 3 PMID:3600374 -1.14.16.1 * caenorhabditis elegans 2.6 2.35 2 PMID:20480196 -1.14.16.1 * callorhinus ursinus 0.247 0.052665 4 PMID:10909822 -1.14.16.1 * chromobacterium violaceum 13.2 3.37 5 PMID:19664549;PMID:2885717;PMID:33985;PMID:3600378 -1.14.16.1 * homo sapiens 3640.0 1.76 23 PMID:10767175;PMID:12379147;PMID:12653545;PMID:15060071;PMID:15917086;PMID:18937047;PMID:19629656;PMID:19653802;PMID:3298976;PMID:4074362;PMID:4854919;PMID:8806757;PMID:9434741 -1.14.16.1 * legionella pneumophila 10.2 10.2 1 PMID:23049981 -1.14.16.1 * macaca fascicularis 0.44 0.44 1 PMID:812698 -1.14.16.1 * pseudomonas fluorescens 3.37 3.37 1 PMID:34868217 -1.14.16.1 * pseudomonas sp. 3.9 3.9 1 PMID:1158876 -1.14.16.1 * rattus norvegicus 12.5 1.8 7 PMID:3600368;PMID:3600372;PMID:7407194;PMID:7436425;PMID:7761394;PMID:8530485 -1.14.16.2 * bos taurus 20.7 0.4175 8 PMID:16885;PMID:2443076;PMID:2885718;PMID:2894860;PMID:6117320;PMID:6127111;PMID:9326301 -1.14.16.2 * caenorhabditis elegans 68800.0 68800.0 1 PMID:21087208 -1.14.16.2 * homo sapiens 1.0 0.245 10 PMID:11076506;PMID:12631248;PMID:21087208;PMID:22659380;PMID:9326301 -1.14.16.2 * mucuna pruriens var. utilis 113.0 107.0 2 PMID:20300771 -1.14.16.2 * mus musculus 0.00045 0.000325 2 PMID:18349104 -1.14.16.2 * oryctolagus cuniculus 0.04 0.04 1 PMID:6119046 -1.14.16.2 * pelophylax lessonae 3.46 3.46 1 PMID:18551654 -1.14.16.2 * rattus norvegicus 1604.0 0.9 8 PMID:18602388;PMID:1967606;PMID:2443076;PMID:2861203;PMID:2885719;PMID:2885720;PMID:6120836;PMID:9326301 -1.14.16.2 * schistosoma japonicum 0.82 0.82 1 PMID:21556690 -1.14.16.2 * schistosoma mansoni 0.78 0.390015 2 PMID:9751167 -1.14.16.4 * bos taurus 0.235 0.235 1 PMID:4429558 -1.14.16.4 * danio rerio 0.0144 0.0144 1 PMID:23754283 -1.14.16.4 * gallus gallus 0.6 0.6 1 PMID:18055219 -1.14.16.4 * homo sapiens 0.6 0.0214 5 PMID:10525150;PMID:14711505;PMID:16654;PMID:17181551 -1.14.16.4 * mus musculus 5.28 5.0 3 PMID:16185653;PMID:3110559;PMID:6809461;PMID:8087417 -1.14.16.4 * oryctolagus cuniculus 0.015 0.0021 3 PMID:1126946;PMID:4402511;PMID:7298604 -1.14.16.4 * pseudomonas fluorescens 0.96 0.96 1 PMID:34868217 -1.14.16.4 * rattus norvegicus 0.374 0.082 5 PMID:1059145;PMID:3600387;PMID:3996408;PMID:7060568;PMID:7298604 -1.14.16.4 * schistosoma mansoni 0.17 0.17 1 PMID:10419488 -1.14.16.4 * thunnus albacares 13.3 13.3 1 PMID:9159879 -1.14.16.5 * rattus norvegicus 0.029 0.029 1 PMID:4383918 -1.14.16.6 * pseudomonas putida 0.021 0.021 1 PMID:9909 -1.14.17.1 * bos taurus 69.0 3.9 3 PMID:3101599;PMID:4778938;PMID:5846992 -1.14.17.1 * rattus norvegicus 1.5 1.5 1 PMID:6733150 -1.14.17.3 * blattella germanica 0.01 0.01 1 PMID:18952446 -1.14.17.3 * bos taurus 1.15 0.0765 4 PMID:3348792;PMID:3944110 -1.14.17.3 * homo sapiens 0.53 0.53 1 PMID:12699694 -1.14.17.3 * mus musculus 8e-05 3.85e-05 6 PMID:19022883 -1.14.17.3 * rattus norvegicus 5.9 6.13e-07 24 PMID:10639739;PMID:11389601;PMID:12646261;PMID:18818385;PMID:18952446;PMID:2211657;PMID:3341777 -1.14.17.3 * sus scrofa 0.0014 0.0014 1 PMID:20715282 -1.14.17.3 * xenopus laevis 16.0 0.43529999999999996 4 PMID:12509982;PMID:2265607;PMID:8319690 -1.14.17.4 * actinidia deliciosa 0.16 0.16 1 PMID:8973637 -1.14.17.4 * malus domestica 0.13 0.02 9 PMID:11361015;PMID:1409700;PMID:24244837;PMID:8391802 -1.14.17.4 * pyrus communis 0.006 0.005350000000000001 2 * -1.14.17.4 * solanum lycopersicum 0.035 0.018500000000000003 4 PMID:9578456 -1.14.18.1 * aeromonas media 34.0 19.0 2 PMID:18931836 -1.14.18.1 * agaricus bisporus 8300.0 3000.0 13 PMID:11991248;PMID:17284853;PMID:17369881;PMID:17518352;PMID:17693955;PMID:17847704;PMID:18341247;PMID:18500813;PMID:18524420;PMID:18647136;PMID:18683821;PMID:25197562;PMID:28500345 -1.14.18.1 * aspergillus terreus 28.1 15.065000000000001 2 PMID:33804376 -1.14.18.1 * calliphora vicina 143.0 143.0 1 PMID:812490 -1.14.18.1 * camellia sinensis 105.0 105.0 1 * -1.14.18.1 * coffea arabica 0.00072 0.00072 1 PMID:16376392 -1.14.18.1 * coffea guarini 0.003 0.001 3 PMID:16376392 -1.14.18.1 * coffea kapakata 0.002 0.00142 2 PMID:16376392 -1.14.18.1 * coffea liberica var. dewevrei 0.004 0.0005 4 PMID:16376392 -1.14.18.1 * coffea stenophylla 0.002 0.0013 2 PMID:16376392 -1.14.18.1 * colocasia esculenta 3000.0 1765.0 2 PMID:32676302 -1.14.18.1 * crocus sativus 900.0 322.5 4 * -1.14.18.1 * dioscorea alata 112488.0 56947.5 2 PMID:32676302 -1.14.18.1 * dioscorea cayenensis subsp. rotundata 15759.0 8252.5 2 PMID:32676302 -1.14.18.1 * dioscorea praehensilis 15275.0 8456.5 2 PMID:32676302 -1.14.18.1 * gallus gallus 106.0 54.17 2 PMID:6432056 -1.14.18.1 * homo sapiens 350.02 26.0 3 PMID:10904869;PMID:28762492;PMID:6814365 -1.14.18.1 * lactuca sativa 1301.0 1301.0 1 PMID:11600037 -1.14.18.1 * lithobates pipiens 72.0 43.5 4 PMID:803496 -1.14.18.1 * lonicera confusa 2847.22 1479.485 2 * -1.14.18.1 * macrolepiota gracilenta 2.625 1.3326 2 * -1.14.18.1 * malus sp. 11330.0 11330.0 1 * -1.14.18.1 * mammalia 45.0 45.0 1 PMID:3110555 -1.14.18.1 * mangifera indica 8839.0 8839.0 1 PMID:25211397 -1.14.18.1 * mesocricetus auratus 45.0 45.0 1 * -1.14.18.1 * mucuna pruriens 658.0 658.0 1 PMID:24253167 -1.14.18.1 * mus musculus 6889.0 2.5 3 PMID:2510599;PMID:415664;PMID:7727517 -1.14.18.1 * neurospora crassa 1205.0 872.5 2 PMID:3037257 -1.14.18.1 * penicillium copticola 23.27 12.68 2 PMID:33804376 -1.14.18.1 * persea americana 442.0 221.0095 2 * -1.14.18.1 * pholiota microspora 412.0 412.0 1 PMID:17617709 -1.14.18.1 * prunus armeniaca 3432.0 3432.0 1 PMID:10198084 -1.14.18.1 * prunus persica 0.45 0.096 5 PMID:17994689 -1.14.18.1 * pseudomonas putida 5.463 0.59375 14 PMID:19624744 -1.14.18.1 * pyrus communis 1480.0 1030.0 3 PMID:16664226 -1.14.18.1 * sarcophaga bullata 772.0 772.0 1 PMID:19669602 -1.14.18.1 * solanum lycocarpum 67.18 12.395 4 * -1.14.18.1 * solanum melongena 336.0 336.0 1 * -1.14.18.1 * spinacia oleracea 32.0 7.2 3 * -1.14.18.1 * streptomyces castaneoglobisporus 1.1 1.1 1 PMID:15003252 -1.14.18.1 * streptomyces cyaneofuscatus 47.6 47.6 1 PMID:29133199 -1.14.18.1 * streptomyces pharetrae 15.07 15.07 1 * -1.14.18.1 * streptomyces polyantibioticus 23.8 23.8 1 * -1.14.18.1 * streptomyces sp. 215.0 172.5 2 PMID:10737179;PMID:3928616 -1.14.18.1 * thermomicrobium roseum 2.49 2.49 1 * -1.14.18.1 * trametes sanguinea 84.34 57.27 2 PMID:15659188 -1.14.18.1 * trifolium pratense 5.94 0.282 6 PMID:18069787 -1.14.18.1 * urtica dioica 42.57 42.57 1 PMID:16119202 -1.14.18.1 * vibrio tyrosinaticus 137.0 91.5 2 PMID:4208174 -1.14.18.1 * vitis vinifera 9854.0 9854.0 1 * -1.14.18.1 * xenopus laevis 10.4 5.915 2 PMID:3930497 -1.14.18.2 * asterias rubens 0.00093 0.00093 1 PMID:12524037 -1.14.18.2 * mus musculus 6.8 3.463 2 PMID:7841794;PMID:8132639 -1.14.18.2 * sus scrofa 0.816 0.816 1 PMID:7881182 -1.14.18.3 * methylococcus capsulatus 0.23 0.07775 12 PMID:12379148;PMID:12634423;PMID:13129946;PMID:16101279;PMID:18052283;PMID:22484247;PMID:22725967;PMID:8576034 -1.14.18.3 * methylocystis sp. 0.0053 0.0053 1 PMID:22013879;PMID:22725967 -1.14.18.3 * methylosinus trichosporium 0.012 0.011 3 PMID:21419924;PMID:22725967 -1.14.18.9 * rattus norvegicus 17.2 0.25178 4 PMID:3949790;PMID:4234469 -1.14.19.1 * arabidopsis sp. 0.8 0.8 1 PMID:11481500 -1.14.19.1 * bos taurus 0.0004 0.0004 1 PMID:4147170 -1.14.19.1 * fusarium oxysporum 0.00044 0.00044 1 PMID:35271 -1.14.19.1 * gallus gallus 0.11 0.10500000000000001 2 PMID:36392;PMID:6116157 -1.14.19.1 * mus musculus 0.0016 0.00075 4 PMID:15855315 -1.14.19.1 * picea glauca 0.0002375 0.0002375 1 PMID:12208502 -1.14.19.1 * rattus norvegicus 0.325 0.0315 5 PMID:15547;PMID:27698;PMID:4373719;PMID:5543646 -1.14.19.1 * sus scrofa 0.0009 0.0009 1 PMID:6849948 -1.14.19.2 * carthamus tinctorius 0.11 0.11 1 PMID:7118934 -1.14.19.2 * cinnamomum longepaniculatum 7.9e-05 4.75e-06 4 * -1.14.19.2 * jatropha curcas 0.00795 0.000826 4 PMID:16642305 -1.14.19.2 * persea americana 0.065 0.065 1 PMID:2006187 -1.14.19.20 * rattus norvegicus 0.022 0.0079 3 PMID:3997841;PMID:4019441 -1.14.19.23 * spinacia oleracea 0.196 0.196 1 PMID:7948918 -1.14.19.25 * mortierella alpina 0.4646 0.2353 3 PMID:29082420 -1.14.19.3 * rattus norvegicus 0.0344 0.0344 1 PMID:7212717 -1.14.19.3 * thunbergia alata 0.1 0.1 1 PMID:9144157 -1.14.19.58 * xenorhabdus szentirmaii 88.8 0.2 7 PMID:31673806 -1.14.19.64 * eschscholzia californica 4.5e-06 4.5e-06 1 PMID:17250743 -1.14.19.77 * mesocricetus auratus 2.8e-06 2.8e-06 1 PMID:4144394 -1.14.19.77 * mus musculus 0.105 0.105 1 PMID:8123685 -1.14.19.77 * rattus norvegicus 2.9e-05 1.58e-05 4 PMID:4357425;PMID:9017521 -1.14.19.9 * lentzea aerocolonigenes 0.29 0.22999999999999998 2 PMID:17260957 -1.14.20.1 * hapsidospora chrysogena 38.5 0.198 8 PMID:12586400;PMID:14734549;PMID:3558321;PMID:3663194;PMID:8865604 -1.14.20.1 * streptomyces clavuligerus 190.0 1.4905 16 PMID:10222202;PMID:12586400;PMID:12631288;PMID:17729280;PMID:18083859;PMID:21909691;PMID:2656705 -1.14.20.1 * streptomyces jumonjinensis 1.551 0.458 9 PMID:12586400 -1.14.20.13 * hyoscyamus niger 0.000198 0.000198 1 * -1.14.20.5 * petroselinum crispum 0.0057 0.00486 2 PMID:11516175;PMID:2221917 -1.14.20.6 * acacia confusa 0.163 0.154 3 * -1.14.20.6 * arabidopsis thaliana 26.9 26.9 1 PMID:17719613 -1.14.20.6 * fagopyrum tataricum 0.019 0.01215 2 PMID:22563787 -1.14.20.7 * pseudomonas syringae 660.0 660.0 1 PMID:1770346 -1.14.99.1 * bos taurus 2.4 2.4 1 PMID:816795 -1.14.99.1 * homo sapiens 4220.0 2110.0029 2 PMID:16401081;PMID:22504626 -1.14.99.1 * ovis aries 43.0 43.0 1 PMID:6766446 -1.14.99.1 * salvelinus fontinalis 15000.0 8650.0 2 PMID:16770009 -1.14.99.15 * pseudomonas putida 487.3 305.2 55 PMID:10998052;PMID:188654;PMID:240720;PMID:4351526 -1.14.99.20 * bos taurus 0.00466 0.002715 2 PMID:2780546;PMID:6277693 -1.14.99.22 * bombyx mori 27.0 27.0 1 PMID:11082204 -1.14.99.22 * drosophila melanogaster 4.33e-06 4.33e-06 1 PMID:1737575 -1.14.99.22 * locusta migratoria migratorioides 3e-06 7.5e-07 5 PMID:27363 -1.14.99.22 * manduca sexta 0.0001721 4.66e-05 3 PMID:1737575 -1.14.99.22 * parasarcophaga argyrostoma 6.17e-09 6.17e-09 1 * -1.14.99.22 * sarcophaga bullata 1.03e-08 1.03e-08 1 * -1.14.99.22 * schistocerca gregaria 1.83e-05 1.196e-05 2 PMID:606249;PMID:6439188 -1.14.99.22 * spinacia oleracea 0.0021 0.0021 1 * -1.14.99.24 * mycolicibacterium fortuitum 6.18 6.18 1 PMID:18982265 -1.14.99.29 * rattus norvegicus 416.0 416.0 1 PMID:2015290;PMID:3076334;PMID:3949761 -1.14.99.39 * acinetobacter sp. 23.2 23.2 1 * -1.14.99.39 * nitrosomonas europaea 0.089 0.089 1 PMID:19453274 -1.14.99.39 * paracoccus denitrificans 8.0 8.0 1 PMID:8654570 -1.14.99.47 * larrea tridentata 2.2 2.2 1 PMID:12960376 -1.14.99.68 * streptomyces thioluteus 0.0032 0.0032 1 PMID:17765264 -1.15.1.1 * acidilobus saccharovorans 1700.0 1700.0 1 PMID:23244732 -1.15.1.1 * aeropyrum pernix 2700.0 195.0 6 PMID:21182595 -1.15.1.1 * allium sativum 89.0 89.0 1 PMID:19205037 -1.15.1.1 * aspergillus glaucus 4000.0 2311.5 2 PMID:27109365 -1.15.1.1 * aspergillus niger 2940.0 2940.0 1 PMID:18395490 -1.15.1.1 * avicennia marina 533.5 533.5 1 PMID:28720545 -1.15.1.1 * bacillus cereus 18.6 13.0 2 PMID:17521361 -1.15.1.1 * bacillus sp. (in: firmicutes) 3538.0 3538.0 1 PMID:21340017 -1.15.1.1 * beauveria bassiana 1331.0 754.85 2 * -1.15.1.1 * bombyx mori 7980.0 4277.0 2 * -1.15.1.1 * caragana jubata 1547.0 1547.0 1 * -1.15.1.1 * caulobacter vibrioides 9523.0 9523.0 1 PMID:16213200 -1.15.1.1 * chloroflexus aurantiacus 572.0 289.0 5 PMID:15150226 -1.15.1.1 * citrullus lanatus 480.0 480.0 1 PMID:17545229 -1.15.1.1 * clostridioides difficile 8600.0 4700.0 2 PMID:24275896 -1.15.1.1 * cordyceps militaris 27270.0 17060.0 3 PMID:16165406 -1.15.1.1 * curcuma aromatica 1250.0 1250.0 1 * -1.15.1.1 * danio rerio 2000.0 2000.0 1 PMID:12876653 -1.15.1.1 * deinococcus radiophilus 31300.0 31300.0 1 PMID:15106001 -1.15.1.1 * deschampsia antarctica 5818.0 5818.0 1 PMID:25638267 -1.15.1.1 * exiguobacterium sp. 10500.0 10500.0 1 PMID:24414928 -1.15.1.1 * geobacillus sp. 1204.0 1204.0 1 PMID:24242973 -1.15.1.1 * haliotis discus 2781.0 2781.0 1 * -1.15.1.1 * homo sapiens 1365.3 745.3 2 PMID:29850654 -1.15.1.1 * humicola lutea 40.21 39.64 3 PMID:17805512 -1.15.1.1 * hyphantria cunea 5780.0 5780.0 1 * -1.15.1.1 * jatropha curcas 151.9 107.65 2 PMID:23586910;PMID:23659174 -1.15.1.1 * kluyveromyces marxianus 996.2 996.2 1 PMID:19758847 -1.15.1.1 * laternula elliptica 1853.0 936.55 2 PMID:19628043 -1.15.1.1 * leishmania amazonensis 615.65 615.65 1 PMID:24440468 -1.15.1.1 * leishmania peruviana 630.61 630.61 1 PMID:24440468 -1.15.1.1 * marinomonas sp. 5672.0 5672.0 1 PMID:16369690 -1.15.1.1 * meretrix meretrix 27.12 27.12 1 PMID:23053968 -1.15.1.1 * metarhizium anisopliae 3839.0 3839.0 1 PMID:15380557 -1.15.1.1 * methanobrevibacter arboriphilus 3970.0 3970.0 1 PMID:16615865 -1.15.1.1 * miscanthus x giganteus 1854.79 1854.79 1 PMID:26334392 -1.15.1.1 * mizuhopecten yessoensis 43160.0 43160.0 1 PMID:16324874 -1.15.1.1 * mycobacterium sp. 2524.0 2524.0 1 PMID:21717325 -1.15.1.1 * nostoc sp. 20.0 20.0 1 PMID:15302891 -1.15.1.1 * panax ginseng 9480.0 9480.0 1 PMID:20954211 -1.15.1.1 * paralichthys olivaceus 500.0 500.0 1 PMID:21199678 -1.15.1.1 * pseudomonas putida 66.0 66.0 1 PMID:10742227 -1.15.1.1 * pyrobaculum calidifontis 1970.0 1960.0 3 PMID:14563869 -1.15.1.1 * radix lethospermi 4843.0 4843.0 1 PMID:15734151 -1.15.1.1 * saccharolobus solfataricus 6720.0 249.15 4 PMID:10601872;PMID:14979716;PMID:9880816 -1.15.1.1 * sardinella aurita 228.19 228.19 1 * -1.15.1.1 * scedosporium apiospermum 1.41 1.41 1 PMID:17395518 -1.15.1.1 * sonneratia alba 2200.0 2200.0 1 PMID:26703583 -1.15.1.1 * stemona tuberosa 83.3 83.3 1 PMID:24279794 -1.15.1.1 * sulfolobus acidocaldarius 3000.0 3000.0 1 PMID:9878438 -1.15.1.1 * tatumella ptyseos 6540.0 6540.0 1 PMID:15721770 -1.15.1.1 * thermoascus aurantiacus 2324.0 1237.0 2 PMID:17420576;PMID:19229500 -1.15.1.1 * thermochaetoides thermophila 2170.0 127.4 3 PMID:18751544;PMID:20823534;PMID:21287231 -1.15.1.1 * thermomyces lanuginosus 1760.0 1760.0 1 PMID:15290327 -1.15.1.1 * thermus thermophilus 1418.0 1418.0 1 PMID:21197558 -1.15.1.1 * triticum aestivum 179.0 146.4 2 PMID:18698793 -1.15.1.1 * trypanosoma cruzi 13960.0 10098.0 4 PMID:18592100 -1.15.1.1 * uncultured bacterium 1890.0 1890.0 1 PMID:17262208 -1.15.1.1 * withania somnifera 4200.0 4200.0 1 PMID:21695487 -1.15.1.1 * yersinia enterocolitica 24400.0 18600.0 2 PMID:23704955 -1.16.1.1 * acidithiobacillus ferrooxidans 12.8 12.8 1 * -1.16.1.1 * azotobacter chroococcum 18.32 18.32 1 * -1.16.1.1 * flavobacterium rigense 6.8 6.8 1 PMID:9527517 -1.16.1.1 * klebsiella pneumoniae 9.0 9.0 1 * -1.16.1.1 * lysinibacillus sphaericus 0.13 0.13 1 PMID:24132860 -1.16.1.1 * metallosphaera sedula 3.1 2.5 2 PMID:26217660 -1.16.1.1 * pseudomonas aeruginosa 6.0 6.0 1 PMID:6277900 -1.16.1.1 * uncultured pseudomonadota bacterium 10.96 10.96 1 PMID:30446558 -1.16.1.1 * yersinia enterolytica 2.08 2.08 1 PMID:8467420 -1.16.1.10 * archaeoglobus fulgidus 3503.0 3503.0 1 PMID:10593977 -1.16.1.2 * rattus norvegicus 0.0057 0.0057 1 PMID:3680232 -1.16.1.6 * euglena gracilis 3.0 3.0 1 * -1.16.1.7 * paracoccus denitrificans 0.97 0.655 2 PMID:22784963 -1.16.1.8 * homo sapiens 1.56 1.56 1 PMID:11466310 -1.16.1.9 * escherichia coli 0.0907 0.0333 11 PMID:21097627;PMID:31868104 -1.16.1.9 * synechocystis sp. 0.91 0.465 2 PMID:21221720 -1.16.2.1 * acidithiobacillus ferrooxidans 0.006 0.006 1 PMID:4288725 -1.16.2.1 * shewanella oneidensis 1.6 1.55 2 PMID:16788180 -1.16.3.1 * acidomyces acidophilus 0.702 0.702 1 PMID:24582726 -1.16.3.1 * anser sp. 3.29 1.79 2 PMID:2829726 -1.16.3.1 * homo sapiens 30.0 1.25 7 PMID:19076073;PMID:2829726;PMID:3993922;PMID:4037797;PMID:4098342 -1.16.3.1 * mus musculus 0.3 0.275 2 PMID:19076073 -1.16.3.1 * sus scrofa 5.72 1.25 3 PMID:2829726 -1.16.3.4 * escherichia coli 201.0 120.0 4 PMID:17804014 -1.17.1.1 * yersinia pseudotuberculosis 0.32 0.215 2 * -1.17.1.10 * burkholderia stabilis 5.3 3.3499999999999996 2 * -1.17.1.10 * neomoorella thermoacetica 1092.0 113.0 5 PMID:4154039;PMID:6311213;PMID:6822536;PMID:713844 -1.17.1.3 * desmodium uncinatum 8.7 8.7 2 PMID:12788945 -1.17.1.3 * onobrychis viciifolia 0.0005 0.0005 1 * -1.17.1.4 * acinetobacter baumannii 29.1 29.1 1 PMID:27537049 -1.17.1.4 * arabidopsis thaliana 1.712 0.6759999999999999 4 PMID:19915948 -1.17.1.4 * arthrobacter luteolus 10.0 10.0 1 PMID:27537049 -1.17.1.4 * bos taurus 1.83 1.56 5 PMID:1328233;PMID:15453470;PMID:27537049 -1.17.1.4 * camelus dromedarius 0.013 0.00705 2 PMID:16026028 -1.17.1.4 * capra hircus 0.27 0.27 2 PMID:15453470 -1.17.1.4 * chlamydomonas reinhardtii 5.69 5.69 1 PMID:1525176 -1.17.1.4 * clostridium cylindrosporum 3.7 3.7 1 PMID:518233 -1.17.1.4 * delftia acidovorans 80.0 50.0 3 PMID:15294283;PMID:8611534 -1.17.1.4 * drosophila melanogaster 1328.0 1.8 3 PMID:1313286;PMID:14264879 -1.17.1.4 * enterobacter cloacae 7.5 7.5 1 PMID:27537049 -1.17.1.4 * escherichia coli 7.0 7.0 1 PMID:27537049 -1.17.1.4 * eubacterium barkeri 164.0 164.0 1 PMID:10491134 -1.17.1.4 * fusarium verticillioides 0.22 0.22 1 PMID:18569337 -1.17.1.4 * gallus gallus 49.9 25.2 7 PMID:18569337;PMID:19654053 -1.17.1.4 * glycine max 2.4 2.4 1 PMID:6960807 -1.17.1.4 * gottschalkia acidurici 385.0 193.9 2 PMID:518233 -1.17.1.4 * gottschalkia purinilytica 2.6 2.6 1 PMID:10860985 -1.17.1.4 * homo sapiens 0.29 0.175 2 PMID:15453470 -1.17.1.4 * lathyrus oleraceus 1.17 1.17 1 * -1.17.1.4 * microsporum canis 0.22 0.22 1 PMID:18569337 -1.17.1.4 * neurospora crassa 0.152 0.152 1 PMID:147274 -1.17.1.4 * ovis aries 0.69 0.44999999999999996 2 PMID:15453470 -1.17.1.4 * penicillium chrysogenum 0.22 0.22 1 PMID:18569337 -1.17.1.4 * pseudomonas putida 163.0 35.2 5 PMID:11341925;PMID:3860496 -1.17.1.4 * pseudomonas synxantha 20.0 20.0 1 * -1.17.1.4 * rattus sp. 2.47 2.47 1 PMID:3478001 -1.17.1.4 * rhodobacter capsulatus 35.9 26.7 2 PMID:27537049 -1.17.1.4 * serratia marcescens 0.22 0.22 1 PMID:18569337 -1.17.1.4 * staphylococcus aureus 0.22 0.22 1 PMID:18569337 -1.17.1.4 * streptomyces cyanogenus 10.6 10.6 1 PMID:479130 -1.17.1.4 * trichoderma viride 0.22 0.22 1 PMID:18569337 -1.17.1.4 * triticum aestivum 0.23 0.23 1 * -1.17.1.4 * veillonella atypica 72.56 36.32 2 PMID:6061702;PMID:8706691 -1.17.1.5 * bacillus sp. (in: firmicutes) 0.83 0.83 1 PMID:5128334 -1.17.1.5 * clostridium sp. 28.8 28.8 1 PMID:4388026 -1.17.1.5 * eubacterium barkeri 20.0 18.0 3 PMID:8278371;PMID:8555176 -1.17.1.5 * neobacillus niacini 2.2 1.37 2 * -1.17.1.5 * pseudomonas fluorescens 672.0 104.0 5 * -1.17.1.8 * bacillus cereus 4.67 4.67 1 PMID:19431 -1.17.1.8 * bacillus subtilis 56.4 56.4 1 PMID:236291 -1.17.1.8 * escherichia coli 398.0 217.5 4 PMID:4151489;PMID:4378965;PMID:7893644 -1.17.1.8 * lactiplantibacillus plantarum 1.153 1.153 1 PMID:16385120 -1.17.1.8 * lysinibacillus sphaericus 0.04 0.0345 2 * -1.17.1.8 * priestia megaterium 6.86 6.86 1 PMID:19431 -1.17.1.8 * staphylococcus aureus 10.1 10.1 1 PMID:20057072 -1.17.1.9 * [candida] boidinii 439.0 2.31 10 PMID:1248477;PMID:18452897;PMID:19077192;PMID:19830418 -1.17.1.9 * [candida] methylica 16.0 16.0 1 PMID:4054127 -1.17.1.9 * ancylobacter aquaticus 9.47 9.47 1 PMID:12784610 -1.17.1.9 * arabidopsis thaliana 1.256 0.058 5 PMID:12806771 -1.17.1.9 * bacillus sp. (in: firmicutes) 6.03 6.03 1 PMID:21848698 -1.17.1.9 * candida methanolica 7.52 7.52 1 * -1.17.1.9 * cupriavidus oxalaticus 32.0 16.23 2 PMID:631130;PMID:7144587 -1.17.1.9 * gelatoporia subvermispora 383.4 383.4 1 * -1.17.1.9 * glycine soja 1.395 1.395 1 PMID:16663314 -1.17.1.9 * kloeckera sp. 0.143 0.143 1 * -1.17.1.9 * komagataella pastoris 8.2 8.2 1 PMID:6808927 -1.17.1.9 * lathyrus oleraceus 4.09 3.885 2 PMID:4372234;PMID:574372 -1.17.1.9 * methylobacterium sp. 1.8 1.8 1 PMID:9020054 -1.17.1.9 * methylorubrum extorquens 73.0 73.0 1 PMID:12605683 -1.17.1.9 * methylosinus trichosporium 32.3 32.3 1 PMID:2376564 -1.17.1.9 * methylotrophic bacterium 11.0 11.0 1 PMID:227687 -1.17.1.9 * moraxella sp. 5.97 5.97 1 PMID:3384805 -1.17.1.9 * mycolicibacterium vaccae 3.24 3.24 1 PMID:15338080 -1.17.1.9 * ogataea angusta 2.83 2.83 1 PMID:1015961 -1.17.1.9 * paracoccus sp. 12-a 7.82 7.82 1 PMID:11999398 -1.17.1.9 * pseudomonas methylica 3.04 3.04 1 PMID:6775422 -1.17.1.9 * pseudomonas sp. 4.55 3.49 2 PMID:2777065 -1.17.1.9 * thiobacillus sp. 7.53 7.53 1 PMID:14586102 -1.17.2.2 * pseudomonas sp. 69.7 69.7 1 PMID:1656935 -1.17.2.3 * desulfovibrio desulfuricans 0.14 0.0655 4 PMID:22526566 -1.17.3.2 * acinetobacter calcoaceticus 4.58 2.5700000000000003 2 PMID:30926462 -1.17.3.2 * arabidopsis thaliana 1.712 0.702 3 PMID:19915948 -1.17.3.2 * arthrobacter sp. 230.0 117.35 2 PMID:24623465;PMID:681279 -1.17.3.2 * bos taurus 51082.2 5.3815 6 PMID:10392571;PMID:25089709;PMID:4352904 -1.17.3.2 * capra hircus 123.0 123.0 1 * -1.17.3.2 * enterobacter cloacae 15.2 15.2 1 * -1.17.3.2 * gallus gallus 49.9 25.9 6 PMID:19654053 -1.17.3.2 * homo sapiens 2.04 1.92 2 PMID:3010873 -1.17.3.2 * mus musculus 8.571 5.2 3 PMID:10545219;PMID:2350174;PMID:437298 -1.17.3.2 * oryctolagus cuniculus 0.278 0.278 1 PMID:235293 -1.17.3.2 * rattus norvegicus 800.0 3.64 5 PMID:11087530;PMID:11913970;PMID:18729039;PMID:4342395 -1.17.3.3 * neobacillus niacini 0.7 0.7 1 * -1.17.3.4 * pseudomonas putida 242.0 242.0 1 PMID:4041238 -1.17.3.5 * sinomonas cyclohexanicum 5.4 2.7225 2 PMID:8281951 -1.17.4.1 * bacillus subtilis 1475.0 135.5 6 PMID:24401092 -1.17.4.1 * bos taurus 0.0237 0.0237 1 PMID:111707 -1.17.4.1 * chlamydia trachomatis 0.18 0.048 3 PMID:10984489 -1.17.4.1 * corynebacterium ammoniagenes 0.034 0.034 1 PMID:9468481 -1.17.4.1 * corynebacterium glutamicum 0.53 0.53 1 PMID:19707921 -1.17.4.1 * escherichia coli 6.3 3.535 4 PMID:3311152;PMID:3511029;PMID:357894 -1.17.4.1 * falseniella ignava 4.083 2.246 2 PMID:31414238 -1.17.4.1 * herpes simplex virus 4.3 4.3 1 PMID:6092726 -1.17.4.1 * kitasatospora aureofaciens 0.1 0.1 1 PMID:8829608 -1.17.4.1 * mus musculus 2750.0 2750.0 1 PMID:16829694 -1.17.4.1 * orthopoxvirus vaccinia 0.122 0.122 1 PMID:8349665 -1.17.4.1 * oryctolagus cuniculus 0.00837 0.00028 3 PMID:5027756;PMID:692387;PMID:7872796 -1.17.4.1 * pseudomonas aeruginosa 116.0 66.0 3 PMID:16829681 -1.17.4.1 * pyrococcus furiosus 0.51 0.51 1 PMID:9012808 -1.17.4.1 * rattus norvegicus 0.015 0.01405 2 PMID:7049335 -1.17.4.1 * saccharomyces cerevisiae 258000.0 0.3 5 PMID:10535923;PMID:22465672;PMID:5459124 -1.17.4.1 * salmonella enterica subsp. enterica serovar typhimurium 0.83 0.5549999999999999 2 PMID:7809142 -1.17.4.1 * tequatrovirus t4 1.09 1.09 1 PMID:4344645 -1.17.4.2 * anabaena sp. 77.25 77.25 1 PMID:6772640 -1.17.4.2 * euglena gracilis 0.167 0.167 1 PMID:4210502 -1.17.4.2 * lactobacillus leichmannii 576.0 16.0 3 PMID:4811061;PMID:5924645;PMID:692388 -1.17.4.2 * thermoplasma acidophilum 0.0018 0.0018 1 PMID:8990160 -1.17.4.4 * bos taurus 5.7e-05 1.96e-05 6 PMID:1731762 -1.17.4.4 * rattus norvegicus 0.718 0.00061 9 PMID:11341364;PMID:11641264;PMID:9448739 -1.17.4.5 * bos taurus 0.235 0.235 1 PMID:3857611 -1.17.5.1 * thauera aromatica 0.18 0.105 2 PMID:10336636;PMID:9575237 -1.17.5.2 * pseudomonas sp. 1530.0 1530.0 1 PMID:17981969 -1.17.5.3 * escherichia coli 196.0 196.0 1 PMID:1099093 -1.17.7.3 * escherichia coli 0.099 0.07200000000000001 2 PMID:16268586 -1.17.7.4 * aquifex aeolicus 6.6 6.6 1 PMID:12482608 -1.17.7.4 * escherichia coli 0.7 0.03 5 PMID:12706830;PMID:15469281 -1.17.9.1 * denitrifying bacterium 0.432 0.432 1 PMID:2722739 -1.17.9.1 * geobacter metallireducens 2.2 0.025 3 PMID:17449613;PMID:18658262 -1.17.9.1 * pseudomonas putida 18.03 8.735 4 PMID:4074695;PMID:588247;PMID:743215 -1.17.9.2 * pseudomonas sp. sg-ms2 28.2 28.2 1 PMID:32198167 -1.17.98.3 * methanobacterium formicicum 447.0 0.0336 6 PMID:3944055;PMID:7061389 -1.17.98.3 * methanobrevibacter ruminantium 0.1 0.1 1 PMID:234935 -1.17.98.4 * archaeoglobus fulgidus 0.4 0.4 1 * -1.17.98.4 * archaeoglobus profundus 0.4 0.4 1 * -1.17.98.4 * escherichia coli 290.0 290.0 1 PMID:2211698 -1.17.98.4 * thermococcus onnurineus 2139.7 2139.7 1 PMID:35660788 -1.17.98.5 * thermoanaerobacter kivui 930.0 915.0 2 PMID:30186365 -1.17.99.2 * azoarcus sp. 0.0224 0.01295 2 PMID:11294876 -1.17.99.3 * oryctolagus cuniculus 0.0453 0.0453 1 PMID:9218493 -1.17.99.4 * klebsiella aerogenes 0.0115 0.0115 1 * -1.17.99.6 * streptococcus thermophilus 290.0 175.0 4 PMID:32871253 -1.18.1.1 * alcanivorax borkumensis 11500.0 11500.0 1 PMID:21714118 -1.18.1.1 * clostridium acetobutylicum 46.0 46.0 1 PMID:526302 -1.18.1.1 * ectopseudomonas oleovorans 86.0 84.0 2 PMID:4335861;PMID:9799514 -1.18.1.1 * megalodesulfovibrio gigas 12.0 12.0 1 PMID:8375383 -1.18.1.2 * alcanivorax borkumensis 1806.0 1806.0 1 PMID:23586955 -1.18.1.2 * anabaena cylindrica 53.9 33.7 4 PMID:6783100 -1.18.1.2 * anabaena sp. 120.0 120.0 1 PMID:6817663 -1.18.1.2 * bacillus subtilis 33.8 33.8 1 PMID:15252706 -1.18.1.2 * cyanidium caldarium 400.0 110.0 7 PMID:17828614 -1.18.1.2 * hydrogenobacter thermophilus 21.2 21.2 1 PMID:19552713 -1.18.1.2 * lathyrus oleraceus 160.8 85.4 2 PMID:535654;PMID:8286951 -1.18.1.2 * limnospira platensis 280.0 85.0 7 PMID:17828614 -1.18.1.2 * phaseolus vulgaris 128.0 64.365 2 PMID:2105079 -1.18.1.2 * pseudomonas putida 5.73 4.025 4 PMID:19114475 -1.18.1.2 * pyrococcus furiosus 275.0 146.0 2 PMID:28705933 -1.18.1.2 * rattus norvegicus 9.255 9.252500000000001 2 PMID:687632 -1.18.1.2 * spinacia oleracea 563.0 79.0 5 PMID:2202597;PMID:4083475;PMID:446754;PMID:922016 -1.18.1.2 * sus scrofa 16.3 16.3 1 PMID:3745205 -1.18.1.2 * synechococcus elongatus 11.0 11.0 1 PMID:12040095 -1.18.1.2 * synechocystis sp. 35.28 5.96 6 PMID:21221720 -1.18.1.2 * triticum aestivum 11110.0 5794.3 4 PMID:18253859 -1.18.1.3 * acetobacterium woodii 50000.0 50000.0 1 PMID:24045950 -1.18.1.3 * methylosinus trichosporium ob3b 0.75 0.75 1 PMID:2768195 -1.18.1.3 * pseudomonas putida 12.3 12.3 1 PMID:7204373 -1.18.1.3 * pseudomonas sp. 397.0 397.0 1 PMID:2294092 -1.18.1.4 * pyrococcus furiosus 20000.0 10500.0 2 PMID:10464233;PMID:11398485 -1.18.1.5 * pseudomonas putida 34.4 34.4 1 PMID:6401738 -1.18.1.6 * bos taurus 22.0 8.8 7 PMID:235468;PMID:7130144;PMID:986153 -1.18.1.6 * sus scrofa 23.05 22.925 2 PMID:913589 -1.18.1.7 * pseudomonas putida 397.0 36.7 5 PMID:2294092;PMID:2294093 -1.18.6.1 * azotobacter vinelandii 2.316 1.52 13 PMID:12885243;PMID:15465817;PMID:20022118;PMID:6930977;PMID:7893691;PMID:9214303;PMID:9642255;PMID:9860864 -1.18.6.1 * bradyrhizobium lupini 0.7 0.565 2 PMID:4215454 -1.18.6.1 * clostridium pasteurianum 1.7 1.45 2 PMID:4670203 -1.18.6.1 * gluconacetobacter diazotrophicus 1.6 1.6 1 PMID:15925553 -1.18.6.1 * klebsiella pneumoniae 2.16 2.082 3 PMID:3512961;PMID:8360623 -1.18.6.1 * nitrospirillum amazonense 2.4 2.1 2 PMID:3864779 -1.18.6.1 * rhodobacter capsulatus 2.4 0.8999999999999999 8 PMID:6799495;PMID:9108249 -1.18.6.1 * xanthobacter autotrophicus 1.26 1.165 2 PMID:207515 -1.18.6.2 * azotobacter chroococcum 1211.0 774.0 2 PMID:2851977 -1.18.6.2 * azotobacter vinelandii 454000.0 229465.0 2 PMID:27928630 -1.19.6.1 * klebsiella pneumoniae 0.027 0.027 1 PMID:8360623 -1.2.1.10 * acetivibrio thermocellus 2.18 1.1700000000000002 2 PMID:25666131 -1.2.1.10 * acinetobacter sp. hbs-2 60.6 60.6 1 * -1.2.1.10 * aeromonas hydrophila 1.7 1.7 1 * -1.2.1.10 * citrobacter sp. s-77 7.36 7.36 1 PMID:26216639 -1.2.1.10 * clostridium beijerinckii 9.62 4.88 3 PMID:2275527 -1.2.1.10 * clostridium kluyveri 48.6 48.6 1 PMID:7458347 -1.2.1.10 * escherichia coli 14.1 8.605 2 PMID:4301680;PMID:7034777 -1.2.1.10 * giardia duodenalis 8.75 8.75 1 PMID:9633598 -1.2.1.10 * leuconostoc mesenteroides 1.7 1.6 3 PMID:15928858 -1.2.1.10 * moorella sp. huc22-1 29.9 11.25 4 PMID:17318639 -1.2.1.10 * propionibacterium freudenreichii 83.7 83.7 1 * -1.2.1.10 * thermoanaerobacter ethanolicus 16.0 16.0 1 PMID:8068002 -1.2.1.10 * thermoanaerobacterium saccharolyticum 0.09 0.07 2 PMID:25666131 -1.2.1.104 * [bacillus] caldolyticus 5.4 5.4 1 PMID:27280986 -1.2.1.104 * ascaris suum 5.8 5.8 1 PMID:3785292 -1.2.1.104 * azotobacter vinelandii 15.0 15.0 1 PMID:6468378 -1.2.1.104 * bacillus subtilis 5.9 5.9 1 * -1.2.1.104 * bos taurus 5.7 5.7 1 PMID:3707519 -1.2.1.104 * escherichia coli 0.2 0.15000000000000002 2 PMID:1204621;PMID:2201286 -1.2.1.104 * geobacillus stearothermophilus 2.4 2.4 1 PMID:7458900 -1.2.1.104 * homo sapiens 60.0 25.9 3 PMID:16436377;PMID:17042496 -1.2.1.104 * lactococcus lactis subsp. lactis 6.6 6.6 1 PMID:1624471 -1.2.1.104 * lathyrus oleraceus 0.0513 0.028075 2 PMID:16665241 -1.2.1.104 * mammalia 0.16 0.0975 2 PMID:11368334 -1.2.1.104 * saccharomyces cerevisiae 0.12 0.12 1 PMID:7030741 -1.2.1.104 * salmonella enterica subsp. enterica serovar typhimurium 41.0 41.0 1 PMID:7052136 -1.2.1.104 * solanum tuberosum 5.6 5.6 1 PMID:9729464 -1.2.1.104 * spinacia oleracea 0.00085 0.00085 1 * -1.2.1.104 * sus scrofa 0.14 0.11250000000000002 2 PMID:1204621 -1.2.1.104 * zea mays 0.00265 0.00265 1 * -1.2.1.104 * zymomonas mobilis 0.12 0.12 1 PMID:9515924 -1.2.1.105 * bos taurus 0.2 0.15000000000000002 2 PMID:16060664 -1.2.1.105 * homo sapiens 5.63 3.0 2 PMID:29752936 -1.2.1.105 * rattus norvegicus 0.7 0.7 1 PMID:16737698 -1.2.1.105 * solanum tuberosum 4.6 4.6 1 PMID:10510296 -1.2.1.105 * sus scrofa 5.58 5.415 2 PMID:5104680 -1.2.1.105 * urocitellus richardsonii 252.0 252.0 1 PMID:32445798 -1.2.1.106 * thermus thermophilus 10.1 10.1 1 PMID:26966182 -1.2.1.107 * spinacia oleracea 80.4 80.4 1 * -1.2.1.107 * thermus thermophilus 5.4 2.7550000000000003 2 * -1.2.1.11 * amycolatopsis mediterranei u32 0.0029 0.0029 1 PMID:10952005 -1.2.1.11 * arabidopsis thaliana 26.0 26.0 1 PMID:11812229 -1.2.1.11 * corynebacterium glutamicum 0.02 0.013 5 PMID:3151991 -1.2.1.11 * escherichia coli 145.0 4.0 12 PMID:2868399;PMID:6102909 -1.2.1.11 * lactiplantibacillus plantarum 2.149 2.149 3 PMID:16385120 -1.2.1.11 * lysinibacillus sphaericus 0.048 0.043 3 * -1.2.1.11 * saccharomyces cerevisiae 73.0 73.0 1 PMID:4145650 -1.2.1.11 * streptomyces clavuligerus 0.373 0.373 1 PMID:15313252 -1.2.1.12 * apis mellifera 60.0 60.0 1 PMID:165383 -1.2.1.12 * arabidopsis thaliana 60.0 55.5 4 PMID:18298409;PMID:22607208 -1.2.1.12 * bos taurus 219.0 195.0 5 PMID:2376595;PMID:2713422;PMID:4313838 -1.2.1.12 * camelus dromedarius 45.1 23.39 2 PMID:17277890 -1.2.1.12 * cavia porcellus 190.0 190.0 1 PMID:16444750 -1.2.1.12 * entamoeba histolytica 0.1767 0.1767 1 PMID:17586498 -1.2.1.12 * geobacillus stearothermophilus 150.0 88.345 2 PMID:16827661;PMID:7408867 -1.2.1.12 * glycine max 145.0 145.0 1 * -1.2.1.12 * haemonchus contortus 46.0 1.0 3 PMID:21205411;PMID:23927077 -1.2.1.12 * haloarcula vallismortis 41.5 41.5 1 * -1.2.1.12 * heyndrickxia coagulans 109.0 109.0 1 PMID:911794 -1.2.1.12 * homo sapiens 620.0 68.1 9 PMID:18298375;PMID:19430704;PMID:25091199;PMID:25936797;PMID:3370218;PMID:7144574;PMID:7447472 -1.2.1.12 * ictidomys tridecemlineatus 146.0 146.0 1 PMID:25374779 -1.2.1.12 * lactococcus lactis ssp. cremoris 4.313 2.195 4 PMID:16696685 -1.2.1.12 * neisseria meningitidis 25.1 2.16 3 PMID:17619949 -1.2.1.12 * nitrosomonas europaea 7.5 7.5 1 PMID:30690134 -1.2.1.12 * oryctolagus cuniculus 100.0 97.9 3 PMID:16444750;PMID:18298409;PMID:805342 -1.2.1.12 * plasmodium falciparum 12.6 12.6 1 PMID:26341815 -1.2.1.12 * pseudomonas sp. phi9 3.6 3.6 1 PMID:18759222 -1.2.1.12 * saccharolobus solfataricus 9.2 9.2 1 PMID:7663406 -1.2.1.12 * saccharomyces cerevisiae 100.0 100.0 1 PMID:18298409 -1.2.1.12 * sardina pilchardus 35.75 18.105 2 PMID:18064387 -1.2.1.12 * solanum tuberosum 1.8 0.275 24 PMID:16798850 -1.2.1.12 * spinacia oleracea 90.0 85.2 2 PMID:18298409 -1.2.1.12 * streptomyces arenae 112.0 72.5 2 PMID:6822480 -1.2.1.12 * sus scrofa 150.0 80.0 3 PMID:15520;PMID:6296621 -1.2.1.12 * tetrahymena pyriformis 26.4 13.559999999999999 2 PMID:17669159 -1.2.1.12 * thermotoga maritima 44.0 44.0 1 PMID:2271518 -1.2.1.12 * thermus aquaticus 16.5 16.25 2 PMID:7408867 -1.2.1.12 * thermus thermophilus 5.4 5.4 1 * -1.2.1.12 * trichoderma koningii 125.0 125.0 1 PMID:2226438 -1.2.1.13 * methanococcus maripaludis 0.026 0.026 1 PMID:8288525 -1.2.1.13 * methanothermus fervidus 49.59 49.59 1 PMID:3569291 -1.2.1.13 * onchocerca volvulus 740.0 740.0 1 PMID:15955451 -1.2.1.13 * saccharolobus solfataricus 9.2 7.084999999999999 2 PMID:7663406;PMID:8521845 -1.2.1.13 * sinapis alba 85.0 85.0 1 PMID:27441 -1.2.1.13 * spinacia oleracea 140.0 15.4 3 PMID:23161 -1.2.1.13 * thermoproteus tenax 17.0 17.0 1 PMID:3121324 -1.2.1.13 * triticum aestivum 1.224 0.24575000000000002 30 PMID:16878554 -1.2.1.15 * pseudomonas aeruginosa 0.203 0.203 1 PMID:13727610 -1.2.1.16 * cereibacter sphaeroides 8.5 8.5 1 PMID:4398452 -1.2.1.16 * cupriavidus necator 0.0457 0.024399999999999998 10 PMID:10564790 -1.2.1.16 * escherichia coli 1.264 0.731 13 PMID:7011797 -1.2.1.16 * euglena gracilis 7.94 7.94 1 PMID:4121 -1.2.1.16 * klebsiella pneumoniae 8.5 0.079 10 PMID:2647149 -1.2.1.16 * pseudomonas putida 40.7 40.7 1 PMID:3355840 -1.2.1.16 * pseudomonas sp. 0.045 0.031 10 PMID:4390503 -1.2.1.16 * saccharomyces cerevisiae 0.5 0.2275 4 PMID:3888627 -1.2.1.17 * alcaligenes sp. 0.144 0.144 1 PMID:1083207 -1.2.1.17 * cupriavidus oxalaticus 7.2 5.7 2 PMID:13738657 -1.2.1.17 * pseudomonas sp. 0.214 0.024 3 PMID:1083207 -1.2.1.18 * rattus norvegicus 1.83 1.83 1 PMID:2768248 -1.2.1.19 * avena sativa 0.001 0.001 1 PMID:12579364 -1.2.1.19 * escherichia coli 0.975 0.15 5 PMID:3510672;PMID:3897201 -1.2.1.19 * glycine max 13.71 13.71 1 * -1.2.1.19 * klebsiella aerogenes 0.024 0.013500000000000002 4 PMID:35512 -1.2.1.19 * pseudomonas aeruginosa 0.122 0.045 7 PMID:3141581 -1.2.1.19 * pseudomonas fluorescens 11.6 11.6 1 * -1.2.1.19 * pseudomonas putida 0.33 0.106 6 PMID:237915 -1.2.1.19 * pseudomonas sp. 0.22 0.22 1 PMID:4817964 -1.2.1.19 * rattus norvegicus 0.2 0.2 1 PMID:7097287 -1.2.1.20 * pseudomonas putida 6.5 6.5 1 * -1.2.1.21 * agrobacterium tumefaciens 0.362 0.33099999999999996 2 * -1.2.1.21 * alcaligenes viscolactis 0.042 0.042 1 * -1.2.1.21 * bacillus licheniformis 1.079 1.079 1 * -1.2.1.21 * bacillus subtilis 1.549 0.9355 2 * -1.2.1.21 * corynebacterium glutamicum 10.39 5.255 2 * -1.2.1.21 * escherichia coli 30.5 0.34 13 PMID:6336729;PMID:6345530 -1.2.1.21 * flavobacterium sp. 0.927 0.927 1 * -1.2.1.21 * klebsiella aerogenes 0.105 0.105 1 * -1.2.1.21 * klebsiella pneumoniae 0.136 0.136 1 * -1.2.1.21 * micrococcus luteus 1.65 1.65 1 * -1.2.1.21 * pimelobacter simplex 0.267 0.1835 2 * -1.2.1.21 * prescottella equi 0.262 0.262 1 * -1.2.1.21 * priestia megaterium 0.325 0.325 1 * -1.2.1.21 * protaminobacter alboflavus 0.825 0.825 1 * -1.2.1.21 * proteus vulgaris 0.187 0.187 1 * -1.2.1.21 * pseudomonas fluorescens 0.11 0.11 1 * -1.2.1.21 * salmonella enterica subsp. enterica serovar typhimurium 0.23 0.23 1 * -1.2.1.22 * azotobacter vinelandii 17.2 11.5 3 PMID:18793327 -1.2.1.22 * escherichia coli 17.0 5.75 4 PMID:27671251;PMID:4310089;PMID:6345530 -1.2.1.22 * leishmania major 0.00051 0.00051 1 PMID:19076214 -1.2.1.22 * methanocaldococcus jannaschii 0.6 0.6 1 PMID:16585745 -1.2.1.22 * saccharomyces cerevisiae 0.392 0.392 1 PMID:3908097 -1.2.1.22 * scheffersomyces stipitis 8.94 3.96 8 PMID:18793327 -1.2.1.22 * trypanosoma brucei 0.00051 0.00051 1 PMID:19076214 -1.2.1.22 * trypanosoma cruzi 0.00048 0.00048 1 PMID:19076214 -1.2.1.23 * bacillus subtilis 1.2 0.14 3 PMID:4322199 -1.2.1.23 * candida albicans 8.27 8.27 1 PMID:24607541 -1.2.1.23 * capra hircus 18.4 18.4 1 PMID:7107625 -1.2.1.23 * homo sapiens 4.65 4.65 1 PMID:2721637 -1.2.1.23 * ovis aries 0.571 0.35219999999999996 2 PMID:4383524;PMID:998 -1.2.1.23 * pseudomonas putida 26.0 26.0 1 * -1.2.1.24 * aspergillus niger 0.277 0.277 1 PMID:25757236 -1.2.1.24 * euglena gracilis 3.25 3.25 1 PMID:4121 -1.2.1.24 * hordeum vulgare subsp. vulgare 269.0 269.0 1 * -1.2.1.24 * lumbricus rubellus 4.56 4.56 1 * -1.2.1.24 * pseudomonas sp. 33.2 33.2 1 PMID:4353628 -1.2.1.24 * rattus norvegicus 27.0 14.56 2 PMID:19091;PMID:7262085 -1.2.1.24 * solanum tuberosum 6.49 6.49 1 PMID:2596851 -1.2.1.24 * sus scrofa 5.3 5.3 1 PMID:217872 -1.2.1.26 * pseudomonas sp. 53.0 53.0 1 PMID:6024771 -1.2.1.27 * pseudomonas aeruginosa 5.0 5.0 1 PMID:4314598 -1.2.1.27 * rattus norvegicus 1.83 1.83 1 PMID:2768248 -1.2.1.28 * acinetobacter calcoaceticus 79.0 12.862 4 PMID:2597133;PMID:3291854;PMID:4656805 -1.2.1.28 * acinetobacter sp. ag1 0.433 0.219 2 PMID:17320356 -1.2.1.28 * flavobacterium sp. 0.005 0.005 1 * -1.2.1.28 * pseudomonas putida 64.0 38.1 4 PMID:21448720;PMID:7868591 -1.2.1.28 * sorbus aucuparia 0.0022 0.0014 2 PMID:19409654 -1.2.1.3 * acanthopagrus schlegelii 8.5 8.5 1 PMID:12604200 -1.2.1.3 * bos taurus 1.339 1.2395 2 PMID:627210;PMID:6651765 -1.2.1.3 * equus caballus 0.8 0.585 2 PMID:7278684 -1.2.1.3 * escherichia coli 38.1 3.21 4 PMID:15808744;PMID:18668238 -1.2.1.3 * homo sapiens 5.5 0.000187 52 PMID:12941160;PMID:18196;PMID:18224440;PMID:18272654;PMID:18450747;PMID:18688716;PMID:20954713;PMID:224930;PMID:3592683;PMID:6189823;PMID:7278684;PMID:8155713 -1.2.1.3 * ipomoea batatas 0.135 0.135 1 * -1.2.1.3 * klebsiella pneumoniae 27.73 15.43 2 * -1.2.1.3 * nocardia sp. 5.4 5.4 1 PMID:2241149 -1.2.1.3 * oryctolagus cuniculus 8.75 4.64185 2 PMID:12941160;PMID:3756202 -1.2.1.3 * ovis aries 0.38 0.29000000000000004 2 PMID:194582;PMID:223840 -1.2.1.3 * pseudomonas aeruginosa 20.0 20.0 1 PMID:6292666 -1.2.1.3 * rattus norvegicus 311.0 20.29 7 PMID:10852;PMID:6480594;PMID:697851 -1.2.1.3 * rhodococcus erythropolis 19.5 19.5 1 PMID:16944126 -1.2.1.3 * saccharomyces cerevisiae 34.0 34.0 1 PMID:213051 -1.2.1.3 * sphingomonas sp. 2.457 1.2 25 PMID:15812642 -1.2.1.30 * amorphotheca resinae 0.008 0.008 1 * -1.2.1.30 * neurospora crassa 0.864 0.864 1 PMID:4389863 -1.2.1.30 * nocadia sp. 5.89 5.89 1 PMID:9171390 -1.2.1.30 * nocardia asteroides 0.035 0.035 1 * -1.2.1.30 * nocardia iowensis 2.1 1.0 6 PMID:17102130;PMID:22578862 -1.2.1.30 * nocardia sp. 0.11 0.11 1 PMID:15006821 -1.2.1.31 * candida maltosa 0.0138 0.0072 3 * -1.2.1.31 * homo sapiens 0.00077 0.00077 1 PMID:2160277 -1.2.1.31 * meyerozyma guilliermondii 0.00996 0.00996 1 * -1.2.1.31 * pseudomonas putida 4.9 4.9 1 PMID:4285660 -1.2.1.31 * pseudomonas sp. 4.9 4.9 1 PMID:4285660 -1.2.1.31 * rattus norvegicus 0.185 0.185 1 PMID:4369906 -1.2.1.31 * rhodococcus sp. (in: high g+c gram-positive bacteria) 1.44 1.44 1 PMID:18343343 -1.2.1.32 * bordetella sp. 0.075 0.0276 6 PMID:17090920 -1.2.1.32 * ectopseudomonas oleovorans 1.62 1.62 1 PMID:9721300 -1.2.1.32 * felis catus 0.0765 0.0765 1 PMID:14275130 -1.2.1.33 * pseudomonas sp. 0.4 0.4 1 PMID:4287371 -1.2.1.36 * homo sapiens 0.13 0.0885 2 PMID:18039331 -1.2.1.36 * rattus norvegicus 0.267 0.265 3 PMID:1527087;PMID:4312676;PMID:8329181 -1.2.1.38 * neurospora crassa 0.953 0.953 1 PMID:2420793 -1.2.1.38 * thermus thermophilus 0.848 0.848 1 PMID:12554952 -1.2.1.39 * achromobacter eurydice 19.0 19.0 1 * -1.2.1.39 * aromatoleum aromaticum 0.21 0.156 2 PMID:24214948 -1.2.1.39 * brevibacterium sp. 4.16 2.2105 2 PMID:17619188 -1.2.1.39 * escherichia coli 41.0 41.0 1 PMID:9043126 -1.2.1.4 * escherichia coli 2.0 2.0 1 PMID:15659684 -1.2.1.4 * gluconobacter oxydans 148.0 148.0 1 * -1.2.1.4 * mus musculus 3.43 2.1415 2 PMID:17567582 -1.2.1.4 * proteus vulgaris 14.6 14.6 1 PMID:13839;PMID:6292665 -1.2.1.4 * saccharomyces cerevisiae 24.0 3.0 3 PMID:23454351;PMID:8615805 -1.2.1.41 * escherichia coli 28.2 13.84 3 PMID:4399189;PMID:7035170 -1.2.1.41 * meiothermus ruber 0.55 0.55 1 * -1.2.1.41 * rattus norvegicus 0.013 0.013 1 * -1.2.1.42 * anas platyrhynchos 0.033 0.033 1 PMID:7887931 -1.2.1.42 * bos taurus 321.0 321.0 1 PMID:4343165 -1.2.1.42 * lathyrus oleraceus 0.96 0.48119999999999996 2 PMID:9126278 -1.2.1.42 * marinobacter nauticus 0.057 0.044 7 PMID:22035211 -1.2.1.42 * porphyromonas gingivalis 2.2 2.2 1 * -1.2.1.44 * glycine max 84.07 50.135 2 PMID:7042334;PMID:7454 -1.2.1.44 * picea abies 17.15 17.15 1 PMID:7042334 -1.2.1.44 * populus tremuloides 0.14 0.1 5 PMID:15870094 -1.2.1.44 * populus x canadensis 1.78 1.78 1 PMID:6365550 -1.2.1.46 * methylococcus capsulatus 234.0 234.0 1 PMID:10206695 -1.2.1.46 * ogataea angusta 27.0 14.45 6 PMID:17098416;PMID:17565589 -1.2.1.46 * pseudomonas aeruginosa 9.87 9.87 1 PMID:24125754 -1.2.1.46 * pseudomonas putida 24.1 16.200000000000003 2 PMID:7461603;PMID:8169197 -1.2.1.46 * pseudomonas sp. 1.0 0.915 2 PMID:29274566 -1.2.1.47 * bos taurus 5.1 2.655 2 PMID:7356654 -1.2.1.47 * mus musculus 0.002138 0.0008715000000000001 6 PMID:16707092 -1.2.1.47 * pseudomonas sp. 15.4 12.4 5 PMID:18175913;PMID:23225139 -1.2.1.47 * rattus norvegicus 0.772 0.772 1 PMID:10702312 -1.2.1.48 * acinetobacter sp. 10.9 10.9 1 PMID:10919810 -1.2.1.48 * candida tropicalis 0.098 0.0932 3 PMID:2280703;PMID:6111299 -1.2.1.48 * homo sapiens 33.3 33.3 1 PMID:9133646 -1.2.1.49 * capra hircus 2.6 2.6 1 PMID:7107625 -1.2.1.49 * ovis aries 0.24 0.235 2 PMID:4383524;PMID:6014 -1.2.1.49 * rattus norvegicus 7.25 7.25 1 PMID:20958;PMID:7144586 -1.2.1.5 * bos taurus 18.92 18.92 1 * -1.2.1.5 * cytophaga sp. 14.1 14.1 1 PMID:12419301 -1.2.1.5 * equus caballus 1.0 0.8 3 PMID:1244351;PMID:7144584 -1.2.1.5 * homo sapiens 46.0 32.95 3 PMID:8260946;PMID:8328987 -1.2.1.5 * klebsiella pneumoniae 1.48 1.48 1 PMID:23775313 -1.2.1.5 * mus musculus 5.51 5.51 1 PMID:8401311 -1.2.1.5 * rattus norvegicus 110.5 9.144 4 PMID:2802624;PMID:3355167;PMID:3933572 -1.2.1.5 * saccharomyces cerevisiae 20.6 10.510000000000002 2 PMID:11589696;PMID:19457;PMID:6755180 -1.2.1.5 * sphingopyxis macrogoltabida 0.49 0.28 2 PMID:15726348 -1.2.1.50 * anas platyrhynchos 33.0 33.0 1 PMID:7887931 -1.2.1.50 * lathyrus oleraceus 0.9 0.9 1 PMID:9126278 -1.2.1.50 * marinobacter nauticus 0.1082 0.0677 5 PMID:22020216 -1.2.1.50 * photobacterium phosphoreum 25.0 25.0 1 * -1.2.1.51 * euglena gracilis 15.3 2.48 6 PMID:2114824;PMID:2508561;PMID:3110154 -1.2.1.51 * moniliella megachiliensis 0.06 0.06 1 PMID:19804861 -1.2.1.54 * vicia faba 49.73 49.73 1 PMID:16663901 -1.2.1.57 * clostridium acetobutylicum 11.1 11.1 1 PMID:3384801 -1.2.1.57 * clostridium saccharoperbutylacetonicum 0.49 0.49 1 * -1.2.1.57 * levilactobacillus brevis 2.5 2.5 1 * -1.2.1.57 * thermoanaerobacterium saccharolyticum 0.67 0.67 1 PMID:24216277 -1.2.1.58 * aromatoleum evansii 7.4 6.25 2 PMID:9490067 -1.2.1.59 * methanothermus fervidus 49.59 49.59 1 PMID:3569291 -1.2.1.59 * pyrococcus furiosus 0.06 0.027000000000000003 4 * -1.2.1.60 * escherichia coli 54.0 44.5 2 PMID:2656390;PMID:6756482 -1.2.1.60 * klebsiella pneumoniae 54.0 54.0 1 PMID:2656390;PMID:6756482 -1.2.1.60 * pseudomonas putida 11.0 5.535 2 PMID:6895079 -1.2.1.61 * pseudomonas sp. 0.44 0.44 1 PMID:22380602 -1.2.1.61 * sphingomonas sp. 0.0031 0.0025 3 PMID:21755281 -1.2.1.62 * comamonas testosteroni 30.0 30.0 1 PMID:9006050 -1.2.1.63 * acinetobacter sp. 7.7 7.7 1 PMID:856571 -1.2.1.64 * daucus carota 0.0384 0.0072 5 PMID:26403287 -1.2.1.65 * pseudomonas putida 85.4 1.6 4 PMID:1151334;PMID:21376550;PMID:4423716 -1.2.1.65 * pseudomonas sp. 36.3 1.38 4 PMID:1151334;PMID:24122667;PMID:7364724;PMID:7558195 -1.2.1.65 * rhodococcus ruber 10.42 8.475 4 PMID:28849423 -1.2.1.65 * stenotrophomonas sp. rmsk 0.23 0.21500000000000002 2 PMID:19543983 -1.2.1.67 * amycolatopsis sp. 0.072 0.0485 2 PMID:23064333 -1.2.1.67 * sphingobium sp. syk-6 4.39 1.605 20 PMID:28294121 -1.2.1.68 * pseudomonas sp. 36.54 36.54 1 PMID:9721273 -1.2.1.69 * streptantibioticus cattleyicolor 0.889 0.889 1 PMID:11571203 -1.2.1.7 * acinetobacter baylyi 22.0 12.6 2 * -1.2.1.7 * pseudomonas fluorescens 2.14 2.14 1 PMID:4383635 -1.2.1.7 * pseudomonas putida 60.2 0.29000000000000004 4 PMID:956122 -1.2.1.7 * thauera sp. 0.132 0.078 4 * -1.2.1.70 * escherichia coli 0.47 0.47 1 PMID:14550647 -1.2.1.70 * hordeum vulgare 0.12 0.12 1 PMID:8799193 -1.2.1.72 * escherichia coli 14.7 14.7 1 PMID:9182530 -1.2.1.73 * rhodopseudomonas palustris 1.7 1.7 1 PMID:15817795 -1.2.1.75 * chloroflexus aurantiacus 80.0 45.0 2 PMID:11948153;PMID:8354269 -1.2.1.75 * metallosphaera sedula 4.6 4.6 1 PMID:17041055 -1.2.1.75 * sulfurisphaera tokodaii 44.0 44.0 1 PMID:17041055 -1.2.1.76 * clostridium kluyveri 41.4 41.4 1 PMID:8444151 -1.2.1.77 * aromatoleum evansii 0.17 0.17 1 PMID:16585753 -1.2.1.78 * alcaligenes faecalis 130.6 130.6 1 * -1.2.1.79 * cupriavidus necator 132.1 73.5 2 PMID:10564790 -1.2.1.79 * escherichia coli 34.0 34.0 1 PMID:18474219 -1.2.1.79 * euglena gracilis 7.9 7.9 1 PMID:4121 -1.2.1.79 * klebsiella pneumoniae 4.1 4.1 1 PMID:2647149 -1.2.1.8 * atriplex hortensis 0.00881 0.005505 18 * -1.2.1.8 * avena sativa 0.0012 0.0012 1 PMID:12736784 -1.2.1.8 * cylindrocarpon didymum 20.5 20.5 1 * -1.2.1.8 * escherichia coli 38.0 38.0 1 PMID:2194570 -1.2.1.8 * leymus chinensis 0.00826 0.00826 1 * -1.2.1.8 * limulus polyphemus 213.0 213.0 1 * -1.2.1.8 * pseudomonas aeruginosa 196.0 0.3535 8 PMID:16054744;PMID:16315011;PMID:9973357 -1.2.1.8 * rattus norvegicus 3.3 3.3 1 PMID:10505788 -1.2.1.8 * spinacia oleracea 3.31 0.311 5 PMID:16661818;PMID:2712575;PMID:3667561 -1.2.1.8 * suaeda salsa 19.63 19.63 1 PMID:17955192 -1.2.1.84 * marinobacter nauticus 0.0632 0.0632 1 PMID:33123518 -1.2.1.84 * rhodococcus jostii 5.3 0.045 7 PMID:28778885 -1.2.1.86 * persicaria minor 241.2 138.0 3 * -1.2.1.87 * klebsiella pneumoniae 8.9 8.9 1 * -1.2.1.87 * listeria monocytogenes 17.0 17.0 1 * -1.2.1.88 * [bacillus] caldotenax 2.7 2.7 1 * -1.2.1.88 * agaricus bisporus 0.0125 0.0125 1 PMID:8979339 -1.2.1.88 * bos taurus 0.55 0.55 1 * -1.2.1.88 * escherichia coli 0.13 0.13 1 PMID:1618807 -1.2.1.88 * geobacillus stearothermophilus 8.0 7.1 3 * -1.2.1.88 * geobacillus thermodenitrificans 3.3 2.95 2 * -1.2.1.88 * hyalomma dromedarii 9.75 0.223 3 PMID:9418013 -1.2.1.88 * lysinibacillus sphaericus 34.1 34.1 1 * -1.2.1.88 * nicotiana plumbaginifolia 0.074 0.07200000000000001 2 * -1.2.1.88 * rattus norvegicus 27.1 0.245 4 PMID:15535970;PMID:2211729;PMID:2865333 -1.2.1.88 * saccharomyces cerevisiae 0.124 0.124 1 PMID:6997271 -1.2.1.88 * salmonella enterica subsp. enterica serovar typhimurium 104.0 104.0 1 PMID:6270100 -1.2.1.88 * solanum tuberosum 44.15 44.15 1 PMID:12223682 -1.2.1.88 * streptomyces coelicolor 22.0 22.0 1 * -1.2.1.89 * picrophilus oshimae 6.0 6.0 1 PMID:16458304 -1.2.1.89 * thermoplasma acidophilum 2.85 2.85 1 PMID:16566751 -1.2.1.9 * arabidopsis thaliana 0.015 0.015 1 PMID:16927206 -1.2.1.9 * bacillus cereus 0.04 0.04 1 PMID:16562377 -1.2.1.9 * bacillus licheniformis 0.099 0.099 1 PMID:16562377 -1.2.1.9 * bacillus sp. (in: firmicutes) 0.038 0.038 1 PMID:16562377 -1.2.1.9 * bacillus thuringiensis 0.01 0.01 1 PMID:16562377 -1.2.1.9 * beta vulgaris 10.7 10.7 1 PMID:220918 -1.2.1.9 * chlamydomonas reinhardtii 8.0 8.0 1 * -1.2.1.9 * clostridioides difficile 0.04 0.04 1 PMID:16562377 -1.2.1.9 * clostridium acetobutylicum 75.0 2.0 3 PMID:12182834;PMID:16562377;PMID:31950445 -1.2.1.9 * clostridium pasteurianum 0.06 0.06 1 PMID:16562377 -1.2.1.9 * clostridium perfringens 0.011 0.011 1 PMID:16562377 -1.2.1.9 * clostridium saccharobutylicum 5.263 5.263 1 PMID:31950445 -1.2.1.9 * clostridium sporogenes 0.037 0.037 1 PMID:16562377 -1.2.1.9 * hevea brasiliensis 32.4 32.4 1 PMID:4405240 -1.2.1.9 * lathyrus oleraceus 0.55 0.55 1 PMID:16658509 -1.2.1.9 * spinacia oleracea 15.0 15.0 1 PMID:3341766 -1.2.1.9 * streptococcus agalactiae 0.09 0.09 1 PMID:16562377 -1.2.1.9 * streptococcus equinus 0.065 0.022 18 PMID:16553827 -1.2.1.9 * streptococcus mutans 53.0 53.0 1 PMID:33184 -1.2.1.9 * streptococcus pyogenes 143.2 71.60849999999999 2 PMID:12841648;PMID:16562377 -1.2.1.9 * streptococcus sp. 0.102 0.102 1 PMID:16562377 -1.2.1.9 * synechococcus sp. 150.5 88.7 2 PMID:8687418 -1.2.1.92 * vibrio variabilis 57.4 57.4 1 PMID:32087198 -1.2.1.94 * aedes aegypti 468.2 206.55 16 PMID:23639754 -1.2.1.96 * ectopseudomonas mendocina 0.17 0.17 1 PMID:2019564 -1.2.1.99 * escherichia coli 32.1 27.35 9 PMID:18668238 -1.2.1.99 * klebsiella pneumoniae 34.08 25.43 6 PMID:22952017 -1.2.2.1 * pseudomonas aeruginosa 760.0 752.0 3 PMID:3038081 -1.2.3.1 * bombyx mori 0.697 0.697 1 PMID:30286706 -1.2.3.1 * bos taurus 1.84 1.84 1 PMID:8537361 -1.2.3.1 * cavia porcellus 0.613 0.0094 3 PMID:20390086;PMID:4051501 -1.2.3.1 * desulfovibrio aminophilus 0.3 0.3 1 PMID:16290059 -1.2.3.1 * desulfovibrio desulfuricans 0.8 0.8 1 PMID:10679276 -1.2.3.1 * macaca fascicularis 188.3 94.55765000000001 2 PMID:17603152 -1.2.3.1 * mesocricetus auratus 0.77 0.77 1 PMID:10598038 -1.2.3.1 * mus musculus 0.88 0.355 13 PMID:10190983;PMID:10377246;PMID:14665639;PMID:28526768;PMID:9015384 -1.2.3.1 * oryctolagus cuniculus 1.91 0.1035 6 PMID:20390086;PMID:2941018;PMID:3778470;PMID:4698232 -1.2.3.1 * pseudomonas sp. 31.1 26.0 3 PMID:14659539;PMID:24980850 -1.2.3.1 * rattus norvegicus 1.8 1.44 2 PMID:17353002 -1.2.3.1 * streptomyces rimosus 21.4 21.4 1 * -1.2.3.1 * sus scrofa 0.11 0.11 1 PMID:4698232 -1.2.3.1 * zea mays 0.137 0.137 1 PMID:12226218 -1.2.3.14 * arabidopsis thaliana 0.635 0.365 10 PMID:23065119 -1.2.3.3 * lactobacillus delbrueckii 1.32 1.32 1 PMID:32448120 -1.2.3.4 * abortiporus biennis 26.3 3.15 18 PMID:18985279;PMID:27337220 -1.2.3.4 * amaranthus spinosus 2.3 2.3 1 * -1.2.3.4 * brucella intermedia 0.454 0.454 1 * -1.2.3.4 * gelatoporia subvermispora 20.0 10.4 5 PMID:10356293;PMID:16000768;PMID:21376010 -1.2.3.4 * helianthus annuus 2.98 2.98 1 * -1.2.3.4 * hordeum vulgare 156.0 21.9 9 PMID:16291738;PMID:17210574;PMID:19763895;PMID:5961854;PMID:9143327;PMID:9765992 -1.2.3.4 * pseudomonas sp. 630.0 630.0 1 * -1.2.3.4 * sorghum sp. 0.39 0.39 1 PMID:8422416 -1.2.3.4 * triticum aestivum 5.75 2.875001 2 PMID:14745556;PMID:17399681 -1.2.3.6 * entamoeba histolytica 2.1 2.1 1 PMID:167776 -1.2.3.7 * arabidopsis thaliana 0.558 0.3125 4 PMID:23065119 -1.2.3.9 * bjerkandera adusta 0.012 0.012 1 PMID:10742235 -1.2.3.9 * nocardia sp. 6.5 6.5 1 PMID:9852085 -1.2.3.9 * streptomyces viridosporus 0.15 0.09 11 * -1.2.4.1 * bos taurus 15.8 0.1416 3 PMID:7756842 -1.2.4.1 * enterobacter cloacae 0.011 0.008369999999999999 2 * -1.2.4.1 * escherichia coli 1791.0 0.445 5 PMID:11583990;PMID:15518552;PMID:7011811 -1.2.4.1 * geobacillus stearothermophilus 0.17 0.17 1 PMID:14644451 -1.2.4.1 * homo sapiens 14.4 0.1835 10 PMID:7756842;PMID:9787790 -1.2.4.1 * pseudomonas putida 87.0 87.0 1 * -1.2.4.1 * rattus norvegicus 3.26 3.26 1 PMID:9787790 -1.2.4.1 * sus scrofa 11.0 11.0 1 PMID:956154 -1.2.4.1 * zymomonas mobilis 91.0 73.0 2 PMID:15876566 -1.2.4.2 * escherichia coli 0.775 0.0429 3 * -1.2.4.2 * urocitellus richardsonii 252.0 252.0 1 PMID:32445798 -1.2.4.4 * bos taurus 12.0 7.15 4 PMID:283398;PMID:3071712;PMID:3241565;PMID:447664 -1.2.4.4 * oryctolagus cuniculus 3.2 3.2 1 PMID:7142221 -1.2.4.4 * pseudomonas putida 38.0 26.0 3 PMID:7298579;PMID:8521848 -1.2.4.4 * rattus norvegicus 7.46 5.325 2 PMID:3619032;PMID:6288017 -1.2.4.4 * saccharomyces cerevisiae 0.82 0.82 1 PMID:10989447;PMID:8136709 -1.2.5.1 * escherichia coli 270.0 270.0 1 PMID:11170450 -1.2.5.1 * escherichia coli k-12 90.0 90.0 1 PMID:1100621 -1.2.5.2 * acetobacter aceti 654.0 654.0 1 * -1.2.5.2 * acetobacter pasteurianus 0.318 0.066 5 * -1.2.5.2 * acetobacter sp. 293.0 293.0 1 PMID:16636451 -1.2.5.2 * cupriavidus necator 39.7 39.7 1 PMID:9406410 -1.2.5.2 * gluconacetobacter diazotrophicus 258.0 258.0 1 PMID:18321602 -1.2.5.2 * gluconobacter oxydans 430.0 430.0 1 * -1.2.5.2 * pseudomonas putida 26.8 20.4 2 PMID:7730276 -1.2.5.2 * rhizorhabdus wittichii 2470.0 1450.0 9 PMID:23828599 -1.2.5.2 * thauera butanivorans 4.8 0.0075 4 PMID:11238982 -1.2.5.3 * aeropyrum pernix 2.47 2.2750000000000004 4 * -1.2.5.3 * afipia carboxidovorans 2.6 1.45 2 PMID:29676148 -1.2.5.3 * bradyrhizobium japonicum 0.058 0.058 1 PMID:10788353 -1.2.7.1 * archaeoglobus fulgidus 0.7 0.415 2 PMID:11702074 -1.2.7.1 * archaeoglobus lithotrophicus 0.04 0.04 1 * -1.2.7.1 * archaeoglobus profundus 0.06 0.06 1 * -1.2.7.1 * chlamydomonas reinhardtii 12.0 4.5 7 PMID:23154536 -1.2.7.1 * desulfocurvibacter africanus 72.0 72.0 1 PMID:31276306 -1.2.7.1 * giardia duodenalis 40.0 40.0 1 PMID:8855555 -1.2.7.1 * hydrogenobacter thermophilus 3.46 3.46 1 PMID:9094223 -1.2.7.1 * methanococcus maripaludis 7.4 5.05 4 PMID:12743680 -1.2.7.1 * pseudothermotoga hypogea 119.0 119.0 1 PMID:26032540 -1.2.7.1 * pyrococcus furiosus 20.0 20.0 1 PMID:8380721 -1.2.7.1 * thermoanaerobacter kivui 27.2 14.5 2 PMID:33660937 -1.2.7.1 * thermococcus guaymasensis 20.2 20.2 1 PMID:24982594 -1.2.7.1 * thermococcus kodakarensis 21.9 21.9 1 * -1.2.7.1 * thermotoga maritima 78.0 78.0 1 PMID:26032540 -1.2.7.10 * neomoorella thermoacetica 0.6 0.4 3 PMID:14769464;PMID:20956531 -1.2.7.11 * saccharolobus solfataricus 52.6 52.6 1 PMID:16466637 -1.2.7.11 * sulfolobus acidocaldarius 10.0 10.0 1 PMID:31276306 -1.2.7.12 * archaeoglobus fulgidus 15.0 7.85 2 * -1.2.7.12 * archaeoglobus lithotrophicus 0.01 0.01 1 * -1.2.7.12 * archaeoglobus profundus 0.43 0.43 1 * -1.2.7.12 * ferroglobus placidus 0.2 0.2 1 PMID:9000337 -1.2.7.12 * methanosarcina barkeri 34.0 34.0 1 PMID:2759240 -1.2.7.12 * methanothermobacter wolfeii 27.3 27.3 1 PMID:1330558 -1.2.7.3 * hydrogenobacter thermophilus 35.2 10.67 4 PMID:11401501;PMID:11890705;PMID:14652015;PMID:8655524 -1.2.7.3 * prosthecochloris vibrioformis f. thiosulfatophilum 1.25 1.25 1 PMID:4628267 -1.2.7.3 * thauera aromatica 4.8 4.8 1 PMID:12081970 -1.2.7.3 * thermococcus litoralis 22.3 11.225 2 PMID:8830683 -1.2.7.4 * aeropyrum pernix 2.47 2.265 4 * -1.2.7.4 * archaeoglobus fulgidus 5.7 3.0500000000000003 4 PMID:16349231 -1.2.7.4 * archaeoglobus lithotrophicus 0.04 0.04 1 * -1.2.7.4 * autotrophic methanogenic bacterium 0.4 0.4 1 * -1.2.7.4 * bradyrhizobium japonicum 0.0577 0.0577 1 PMID:10788353 -1.2.7.4 * carboxydothermus hydrogenoformans 14000.0 9962.0 2 PMID:11509720;PMID:12423371 -1.2.7.4 * ferroglobus placidus 0.1 0.1 1 PMID:9000337 -1.2.7.4 * methanococcus vannielii 190.0 190.0 1 PMID:3624199 -1.2.7.4 * methanosarcina barkeri 216.0 133.6 3 PMID:3818661;PMID:6425262;PMID:8399227 -1.2.7.4 * methanosarcina mazei 320.0 320.0 1 PMID:8662887 -1.2.7.4 * methanosarcina thermophila 33.0 33.0 1 PMID:1526465 -1.2.7.4 * methanothermobacter thermautotrophicus 0.4 0.4 1 PMID:21159 -1.2.7.4 * methanothrix soehngenii 117.0 117.0 1 PMID:2714294 -1.2.7.4 * mycobacterium sp. 0.006 0.006 1 PMID:17707766 -1.2.7.4 * mycobacterium tuberculosis 0.0099 0.0099 1 PMID:17707766 -1.2.7.4 * mycolicibacterium vaccae 0.0175 0.0175 1 PMID:17707766 -1.2.7.4 * neomoorella thermoacetica 675.0 200.0 9 PMID:1334436;PMID:15839681;PMID:1995618;PMID:6687389;PMID:8639680 -1.2.7.4 * rhodospirillum rubrum 12000.0 6230.0 3 PMID:11814363;PMID:16283394;PMID:3029096 -1.2.7.4 * thermacetogenium phaeum 163.0 119.9 2 PMID:15866934 -1.2.7.5 * aromatoleum aromaticum 25.1 10.3 15 PMID:24214948;PMID:30766522 -1.2.7.5 * caldicellulosiruptor bescii 48.3 48.3 1 PMID:31097544 -1.2.7.5 * pyrobaculum aerophilum 6.5 6.5 1 PMID:15772818 -1.2.7.5 * pyrococcus furiosus 53.6 42.0 3 PMID:1907273;PMID:9973343 -1.2.7.5 * thermoanaerobacter sp. x514 0.26 0.26 1 PMID:29987342 -1.2.7.5 * thermococcus sp. 238.0 238.0 1 PMID:7642503 -1.2.7.6 * archaeoglobus fulgidus 0.07 0.07 1 PMID:11702074 -1.2.7.6 * caldicellulosiruptor bescii 48.3 48.3 1 PMID:31097544 -1.2.7.6 * methanococcus maripaludis 120.0 60.9 2 PMID:17704226 -1.2.7.6 * pyrobaculum aerophilum 17.0 8.6875 4 PMID:17559573 -1.2.7.6 * pyrococcus furiosus 140.0 27.5 4 PMID:10580093;PMID:11265456;PMID:7721730;PMID:9774434 -1.2.7.7 * methanothermobacter thermautotrophicus 13.8 13.8 1 PMID:9108258 -1.2.7.7 * thermococcus litoralis 46.0 23.5 2 PMID:8550513 -1.2.7.7 * thermococcus profundus 128.0 4.05 4 PMID:15713889 -1.2.7.8 * methanothermobacter thermautotrophicus 31.15 31.15 1 PMID:9108258 -1.2.7.8 * pyrococcus furiosus 38.0 38.0 1 PMID:8206994 -1.2.7.8 * thermococcus profundus 121.0 104.0 4 PMID:22608551 -1.2.98.1 * pseudomonas putida 6000.0 193.0 5 PMID:11866124;PMID:1366532;PMID:7766017 -1.2.99.6 * megalodesulfovibrio gigas 38.5 38.5 1 PMID:7592385 -1.2.99.6 * neomoorella thermoacetica 11.8 11.8 1 PMID:2550230 -1.2.99.6 * peptoclostridium acidaminophilum 19.6 19.6 1 PMID:14686934 -1.2.99.6 * pyrococcus furiosus 53.6 53.6 1 PMID:1907273 -1.2.99.6 * thermococcus sp. 221.0 221.0 1 PMID:7642503 -1.2.99.7 * megalodesulfovibrio gigas 38.5 19.835 2 PMID:7592385;PMID:8218223 -1.2.99.7 * oleidesulfovibrio alaskensis 0.58 0.58 1 PMID:10727945 -1.20.1.1 * pseudomonas sp. 3.49 3.49 1 PMID:22238013 -1.20.1.1 * stutzerimonas stutzeri 12.2 5.2 5 PMID:11278981;PMID:11456941 -1.20.2.1 * hydrogenophaga sp. 5.6 5.6 1 PMID:15178476 -1.20.4.1 * arabidopsis thaliana 3.55 2.775 2 PMID:15834011 -1.20.4.1 * oryza sativa 3.84 3.145 2 PMID:15834011 -1.20.4.1 * pteris vittata 24.0 14.4 2 PMID:15834011 -1.20.4.2 * homo sapiens 0.42 0.375 2 PMID:15970797 -1.20.4.4 * staphylococcus aureus 0.2 0.2 1 PMID:8003493 -1.20.9.1 * alcaligenes faecalis 2.88 2.88 1 PMID:1331097 -1.20.9.1 * chrysiogenes arsenatis 7013.0 7013.0 1 PMID:9738904 -1.20.99.1 * chrysiogenes arsenatis 116.1 116.1 1 PMID:9738904 -1.20.99.1 * homo sapiens 0.0007 0.0007 1 * -1.20.99.1 * hydrogenophaga sp. nt14 5.6 5.6 1 PMID:15178476 -1.20.99.1 * pseudomonas sp. 12.15 9.415 2 PMID:19950002 -1.21.1.1 * bos taurus 7800.0 7800.0 1 PMID:500717 -1.21.1.1 * microhyla ornata 157.7 28.4 13 PMID:19456371 -1.21.1.1 * sus scrofa 3100.0 3100.0 1 PMID:16316988 -1.21.1.2 * clavibacter sepedonicus 0.0008 0.0008 1 PMID:8626335 -1.21.3.1 * aspergillus nidulans 6.64e-06 6.64e-06 1 PMID:11094156 -1.21.3.1 * flavobacterium sp. 0.00129 0.00129 1 PMID:2793834 -1.21.3.1 * hapsidospora chrysogena 1.36e-05 8.15e-06 2 PMID:8557701;PMID:9826554 -1.21.3.1 * streptomyces clavuligerus 3.38e-07 3.38e-07 1 PMID:8776857 -1.21.3.1 * streptomyces microflavus 9.3e-08 9.3e-08 1 PMID:10721485 -1.21.3.4 * penicillium glabrum 1.33 1.215 2 PMID:7049104;PMID:8820909 -1.21.3.5 * oospora sulphurea-ochracea 1.2 1.2 1 PMID:7049104 -1.21.3.6 * antirrhinum majus 578.0 578.0 1 PMID:11073455 -1.21.3.7 * cannabis sativa 0.41 0.244 2 PMID:17669365 -1.21.3.8 * cannabis sativa 9.0 4.5875 2 PMID:8663284 -1.21.4.1 * acetoanaerobium sticklandii 20.4 2.71 5 PMID:10085076;PMID:1262330;PMID:13475375;PMID:5778643;PMID:8203910 -1.21.4.2 * acetoanaerobium sticklandii 5.5 5.5 1 PMID:762072 -1.21.4.2 * peptoclostridium acidaminophilum 352.0 201.65 2 PMID:10091582;PMID:1587286 -1.21.4.3 * peptoclostridium acidaminophilum 229.0 217.0 3 PMID:8529639 -1.21.4.3 * peptoclostridium litorale 114.0 114.0 1 PMID:8529639 -1.21.4.4 * peptoclostridium acidaminophilum 0.117 0.117 1 * -1.21.4.5 * rhizorhabdus dicambivorans 23.24 21.2 2 PMID:29934333 -1.21.4.5 * sphingobium sp. ug30 103.0 103.0 1 PMID:12459186 -1.21.99.1 * penicillium cyclopium 0.058 0.058 1 PMID:5143339 -1.21.99.3 * homo sapiens 6e-07 3.2499999999999996e-07 2 PMID:19548001 -1.21.99.3 * rattus norvegicus 4.2e-05 2.1119999999999998e-05 2 PMID:1417847;PMID:7664675 -1.21.99.4 * bos taurus 0.0002 0.0002 1 PMID:1639026 -1.21.99.4 * cavia porcellus 0.002 0.002 1 PMID:1639026 -1.21.99.4 * gallus gallus 0.0002 0.0002 1 PMID:1639026 -1.21.99.4 * homo sapiens 0.0001 5.43e-08 11 PMID:1639026;PMID:17244789;PMID:18349068;PMID:18514391 -1.21.99.4 * mus musculus 0.0004 1.02e-07 27 PMID:1639026;PMID:19036878;PMID:19929143 -1.21.99.4 * ovis aries 0.0001 0.0001 1 PMID:1639026 -1.21.99.4 * rattus norvegicus 9e-08 2.5e-08 5 PMID:17615150 -1.21.99.4 * rattus sp. 2.0 1.1 2 PMID:10829019 -1.21.99.4 * sus scrofa 0.0003 0.0003 1 PMID:1639026 -1.21.99.5 * dehalobacter restrictus 13.6 11.9 3 PMID:12902251;PMID:8636034;PMID:9224702 -1.21.99.5 * dehalococcoides mccartyi 20.5 20.5 1 PMID:10671186 -1.21.99.5 * desulfitobacterium hafniense 39.0 39.0 1 PMID:9575235 -1.21.99.5 * desulfitobacterium sp. 113.6 113.6 1 PMID:15959725 -1.21.99.5 * paraclostridium bifermentans 0.086 0.086 1 PMID:11400736 -1.21.99.5 * sulfurospirillum multivorans 158.4 158.4 1 PMID:8663199 -1.23.1.1 * forsythia x intermedia 82.18 0.255 3 PMID:8262939;PMID:8910615 -1.23.1.1 * novosphingobium aromaticivorans 61.0 46.5 2 PMID:23199737 -1.23.1.1 * sphingobium sp. 46.0 46.0 1 PMID:23199737 -1.23.1.2 * forsythia x intermedia 131.4 0.255 3 PMID:8262939;PMID:8910615 -1.23.5.1 * lactuca sativa 916.0 916.0 1 PMID:8742341 -1.23.5.1 * phyllostachys edulis 0.015 0.015 1 PMID:23640082 -1.23.5.1 * spinacia oleracea 19.0 19.0 1 * -1.3.1.1 * homo sapiens 0.318 0.184 5 PMID:8194165 -1.3.1.1 * rattus norvegicus 0.535 0.535 1 PMID:1260500 -1.3.1.10 * bacillus subtilis 0.3 0.24 4 PMID:11007778 -1.3.1.10 * candida tropicalis 20.0 20.0 1 PMID:12614607 -1.3.1.10 * escherichia coli 2.31 0.4 3 PMID:9022698 -1.3.1.10 * streptococcus pneumoniae 0.066 0.066 1 PMID:10910344 -1.3.1.10 * streptomyces collinus 3.667 2.2744999999999997 2 PMID:8955309 -1.3.1.101 * thermoplasma acidophilum 0.0115 0.0115 1 PMID:16788058 -1.3.1.102 * nicotiana tabacum 5300.0 4.6 3 PMID:11117876 -1.3.1.102 * plagiochasma appendiculatum 0.0237 0.0102 4 PMID:23954295 -1.3.1.103 * burkholderia sp. 2.8 2.3499999999999996 2 PMID:15781461 -1.3.1.104 * staphylococcus aureus 0.66 0.66 1 PMID:26538431 -1.3.1.11 * arthrobacter sp. 0.56 0.56 1 PMID:14269315 -1.3.1.116 * [clostridium] scindens 48.36 16.4 3 PMID:18047844;PMID:8491719 -1.3.1.119 * xanthobacter flavus 63.0 47.5 2 PMID:8599538 -1.3.1.12 * cupriavidus necator 8.9 8.9 1 PMID:1262315;PMID:3037266 -1.3.1.12 * escherichia coli 98.0 52.0 5 PMID:12581215;PMID:16269762;PMID:3298984;PMID:6342665;PMID:6395895;PMID:7049251 -1.3.1.12 * klebsiella aerogenes 33.0 33.0 1 PMID:206281 -1.3.1.12 * pleurotus ostreatus 300000.0 180000.0 2 PMID:30771296 -1.3.1.12 * saccharomyces cerevisiae 30000.0 21000.0 2 PMID:30771296 -1.3.1.12 * streptococcus mutans 12.6 12.6 1 * -1.3.1.120 * streptomyces collinus 3667.0 3667.0 1 PMID:8955309 -1.3.1.124 * bos taurus 0.00882 0.005815 2 PMID:729581 -1.3.1.124 * homo sapiens 7.21 0.0084 5 PMID:14550650;PMID:2332510 -1.3.1.124 * mus musculus 20.0 2.4000000000000004 4 PMID:10464321;PMID:19578400 -1.3.1.124 * rattus norvegicus 4.1 0.042749999999999996 8 PMID:10497069;PMID:2042025;PMID:7461116 -1.3.1.124 * saccharomyces cerevisiae 1.79 1.79 1 PMID:9268358 -1.3.1.124 * yarrowia lipolytica 2.8 2.8 1 PMID:4019437 -1.3.1.13 * vigna radiata 321.0 321.0 1 PMID:16661043 -1.3.1.14 * lactococcus lactis 5.9 0.055 4 PMID:8021180 -1.3.1.15 * pseudomonas sp. 0.19 0.19 1 PMID:4380263 -1.3.1.16 * penicillium atrovenetum 0.866 0.866 1 * -1.3.1.17 * lathyrus oleraceus 1.51 1.51 1 PMID:6042360 -1.3.1.19 * pseudomonas fluorescens 5.1 2.5989999999999998 2 PMID:20632934 -1.3.1.19 * pseudomonas putida 513.0 153.0 5 PMID:10356973 -1.3.1.19 * pseudomonas sp. 19.1 19.1 1 PMID:4362337 -1.3.1.2 * bos taurus 2.2 1.29 2 PMID:13471594;PMID:1939061 -1.3.1.2 * cupriavidus necator 182.1 182.1 1 PMID:8806723 -1.3.1.2 * homo sapiens 0.318 0.184 5 PMID:8194165 -1.3.1.2 * ovis aries 0.705 0.353365 2 PMID:26758717 -1.3.1.2 * pseudomonas putida 0.00018 0.00018 1 PMID:11759049 -1.3.1.2 * rattus norvegicus 47.4 27.9 7 PMID:7451435 -1.3.1.2 * sus scrofa 21.0 0.43 5 PMID:2806259;PMID:8429016;PMID:9226714;PMID:9860876 -1.3.1.20 * canis sp. 5.65 2.8440000000000003 2 PMID:11306093;PMID:7852295 -1.3.1.20 * homo sapiens 71000.0 11.0 19 PMID:11842089;PMID:15138708;PMID:8543560;PMID:8573067;PMID:9578563 -1.3.1.20 * macaca fascicularis 3.9 1.2 3 PMID:15618685;PMID:17654552 -1.3.1.20 * macaca fuscata 7.11 0.11 3 PMID:11306093;PMID:2697716;PMID:3300644 -1.3.1.20 * macaca fuscata fuscata 3.9 3.9 1 PMID:15618685 -1.3.1.20 * rattus norvegicus 5.525 0.62 3 PMID:2669957;PMID:3516149;PMID:7430089 -1.3.1.20 * sus scrofa 8.0 7.3 3 PMID:11306093 -1.3.1.21 * homo sapiens 0.000605 0.000605 1 PMID:9469584 -1.3.1.21 * rattus norvegicus 0.0023 0.000918 4 PMID:9831636 -1.3.1.22 * digitalis lanata 0.34 0.00014 3 PMID:2106876 -1.3.1.22 * mesocricetus auratus 0.00234 0.00191 2 PMID:7300356 -1.3.1.22 * rattus norvegicus 1090.0 545.017065 2 PMID:7300356 -1.3.1.24 * homo sapiens 0.00075 0.00035 3 PMID:19690164 -1.3.1.24 * rattus norvegicus 3.5 3.5 1 PMID:7217067 -1.3.1.25 * acinetobacter calcoaceticus 108.0 108.0 1 PMID:2824437 -1.3.1.25 * cupriavidus necator 150.0 82.2 2 PMID:4341530;PMID:687665 -1.3.1.25 * pseudomonas putida 89.1 89.1 1 PMID:8824602 -1.3.1.25 * pseudomonas sp. 39.4 39.4 1 PMID:687665 -1.3.1.27 * rattus norvegicus 1.57 0.001305 6 PMID:1150153;PMID:4154890 -1.3.1.28 * escherichia coli 66.0 62.0 2 PMID:2144454;PMID:2521622 -1.3.1.28 * klebsiella aerogenes 0.0046 0.0046 1 PMID:4306838 -1.3.1.29 * corynebacterium sp. 0.103 0.041 9 PMID:8434923 -1.3.1.29 * nocardia sp. 0.19 0.19 1 PMID:62750 -1.3.1.29 * pseudomonas putida 26.0 0.62 21 PMID:2684156;PMID:2684157;PMID:4369091;PMID:62750;PMID:6296054 -1.3.1.29 * rhodococcus sp. (in: high g+c gram-positive bacteria) 0.0041 0.0041 1 PMID:10620687 -1.3.1.3 * digitalis lanata 1.89 1.89 1 PMID:18032383 -1.3.1.3 * pelophylax lessonae 3.6e-06 3.6e-06 1 PMID:4152608 -1.3.1.3 * rattus norvegicus 0.0354 0.034 5 PMID:3828348;PMID:6736016 -1.3.1.3 * sus scrofa 13.1 6.5500834999999995 2 PMID:4396256 -1.3.1.31 * clostridium sp. 6.9 6.9 1 PMID:477658 -1.3.1.31 * clostridium sporogenes 0.174 0.174 1 PMID:29111967 -1.3.1.31 * clostridium tyrobutyricum 20.0 15.3 2 PMID:4005048 -1.3.1.31 * kluyveromyces lactis 2.46 2.46 1 * -1.3.1.31 * neomoorella thermoacetica 2.4 2.4 1 PMID:11060310 -1.3.1.31 * pseudomonas putida 25.82 25.82 1 * -1.3.1.31 * yersinia bercovieri 15.81 15.81 1 * -1.3.1.32 * alcaligenes sp. 0.68 0.68 1 * -1.3.1.32 * aspergillus niger 0.65 0.65 1 PMID:6825782 -1.3.1.32 * chlorobenzene-degrading bacterium strain wr1306 0.94 0.94 1 PMID:6712211 -1.3.1.32 * cupriavidus necator 600.0 0.44 12 PMID:14766925;PMID:19684066;PMID:8226615 -1.3.1.32 * cutaneotrichosporon cutaneum 34.2 0.67 3 PMID:571434;PMID:7387635 -1.3.1.32 * pseudomonas aeruginosa 170.0 85.0017 2 PMID:18331335;PMID:8550433 -1.3.1.32 * pseudomonas putida 0.4 0.4 1 * -1.3.1.32 * pseudomonas sp. 582.9 0.8 3 PMID:8407778 -1.3.1.32 * rhizobium sp. 202.0 107.75 2 PMID:17158677;PMID:27040018 -1.3.1.33 * avena sativa 3.3 0.8 3 PMID:6456902 -1.3.1.33 * chlorobaculum tepidum 0.00315 0.00315 1 PMID:18252716 -1.3.1.33 * hordeum vulgare 13.9 7.2 2 PMID:7306062 -1.3.1.34 * bos taurus 3.9 3.9 1 PMID:6749495 -1.3.1.34 * escherichia coli 10.9 9.22 2 PMID:18171025;PMID:6749495 -1.3.1.34 * homo sapiens 7.21 7.21 1 PMID:14550650 -1.3.1.34 * saccharomyces cerevisiae 1.79 1.79 1 PMID:9268358 -1.3.1.36 * catharanthus roseus 0.000168 0.000168 1 * -1.3.1.37 * escherichia coli 0.0005 0.0005 1 PMID:43196 -1.3.1.38 * caenorhabditis elegans 3.21 3.21 2 PMID:19924289 -1.3.1.38 * cavia porcellus 0.346 0.21059999999999998 2 PMID:10811639 -1.3.1.38 * escherichia coli 20.0 10.245 2 PMID:6378898;PMID:6754111 -1.3.1.38 * rattus norvegicus 0.065 0.05 3 PMID:6815194;PMID:6870879 -1.3.1.40 * pseudomonas sp. 'cruciviae' 2.5 0.049 3 * -1.3.1.41 * drosophila melanogaster 51.0 29.0 2 * -1.3.1.42 * arabidopsis thaliana 26.9 2.5 7 PMID:31834385 -1.3.1.43 * [brevibacterium] flavum 0.0134 0.0134 1 PMID:6929482 -1.3.1.43 * actinomadura citrea 0.0095 0.0095 1 * -1.3.1.43 * actinoplanes auranticolor 0.4 0.4 1 * -1.3.1.43 * actinoplanes campanulatus 0.739 0.739 1 * -1.3.1.43 * actinoplanes missouriensis 0.4 0.4 1 * -1.3.1.43 * actinoplanes philippinensis 0.4 0.4 1 * -1.3.1.43 * dactylosporangium thailandense 0.314 0.314 1 * -1.3.1.43 * micromonospora echinospora 0.005 0.005 1 * -1.3.1.43 * neisseria gonorrhoeae 0.0058 0.00375 2 PMID:2894820 -1.3.1.43 * phenylobacterium immobile 95.5 95.5 1 PMID:3967752 -1.3.1.43 * pilimelia terevasa 0.287 0.287 1 * -1.3.1.43 * planobispora longispora 1.233 1.233 1 * -1.3.1.43 * planomonospora venezuelensis 0.93 0.93 1 * -1.3.1.43 * spirillospora albida 0.695 0.695 1 * -1.3.1.43 * streptomyces anthocyanicus 0.3 0.3 1 * -1.3.1.43 * streptomyces phaeochromogenes 18.8 18.8 1 PMID:4074498 -1.3.1.43 * streptosporangium roseum 0.021 0.021 1 * -1.3.1.43 * synechocystis sp. 0.0083 0.0083 1 PMID:6108316 -1.3.1.43 * zymomonas mobilis 8.825 5.9624999999999995 2 PMID:7916685 -1.3.1.44 * butyrivibrio fibrisolvens 0.79 0.79 1 PMID:35524 -1.3.1.44 * euglena gracilis 3.88 0.66 9 PMID:15569691;PMID:3102464 -1.3.1.44 * mycolicibacterium smegmatis 17.54 8.9455 2 PMID:7251572;PMID:7451405 -1.3.1.44 * rattus norvegicus 0.027 0.02 3 PMID:6870879 -1.3.1.44 * treponema denticola 43.0 43.0 1 PMID:17382934 -1.3.1.45 * cicer arietinum 0.012 0.012 1 * -1.3.1.46 * fusarium solani-melongenae 0.355 0.355 1 * -1.3.1.48 * bos taurus 1.067 0.000945 7 PMID:224937;PMID:6290839;PMID:8382144 -1.3.1.48 * homo sapiens 0.425 0.393 3 PMID:204253;PMID:241339;PMID:7132753 -1.3.1.48 * mus musculus 0.2309 0.19240000000000002 4 PMID:17449869 -1.3.1.48 * rattus norvegicus 2.05 2.05 1 PMID:7693121 -1.3.1.48 * sus scrofa 2.6 2.58 2 * -1.3.1.49 * alcaligenes faecalis 70.7 70.7 1 * -1.3.1.5 * cucurbita maxima 5812.0 5812.0 1 PMID:5640163 -1.3.1.54 * pseudomonas denitrificans (nom. rej.) 0.127 0.127 1 PMID:1732193 -1.3.1.56 * comamonas testosteroni 46.0 31.7 2 PMID:10819967;PMID:8702262 -1.3.1.57 * eubacterium oxidoreducens 4.18 3.13 2 PMID:3571153 -1.3.1.6 * ascaris suum 43.0 34.4 3 PMID:17933581 -1.3.1.6 * bacteroides fragilis 26.0 26.0 1 PMID:12777495 -1.3.1.6 * clostridium formicaceticum 20.6 20.6 1 PMID:214050 -1.3.1.6 * echinococcus multilocularis 0.045 0.045 1 PMID:17954696 -1.3.1.6 * enterococcus faecalis 0.23 0.23 1 PMID:4960892 -1.3.1.6 * fibrobacter succinogenes 0.2 0.2 1 * -1.3.1.6 * lactococcus lactis 2.7 2.7 1 PMID:44997 -1.3.1.6 * leishmania donovani 2189.0 1094.5085 2 PMID:11846720;PMID:12223208 -1.3.1.6 * ruminobacter amylophilus 0.84 0.49 2 PMID:4074073 -1.3.1.6 * trypanosoma brucei 0.142 0.11199999999999999 2 PMID:12223208 -1.3.1.6 * trypanosoma cruzi 0.017 0.016 2 PMID:12223208 -1.3.1.62 * desulfovibrio sp. 1.144 1.144 1 * -1.3.1.62 * syntrophus aciditrophicus 1.144 0.8624999999999999 2 PMID:11282627 -1.3.1.67 * pseudomonas putida 0.067 0.067 1 PMID:3711022 -1.3.1.7 * pseudomonas putida 0.354 0.354 1 * -1.3.1.70 * rattus norvegicus 0.0555 0.054150000000000004 2 PMID:6444198;PMID:7492613 -1.3.1.71 * saccharomyces cerevisiae 0.74 0.37016 2 PMID:10722850;PMID:17225097 -1.3.1.72 * rattus norvegicus 0.0015 0.0015 1 PMID:9291139 -1.3.1.74 * rattus norvegicus 115.9 0.803 5 PMID:14977853;PMID:18274955 -1.3.1.75 * chlorobaculum tepidum 1.1 1.1 1 PMID:32180325 -1.3.1.75 * hordeum vulgare 0.17 0.17 1 PMID:11488624 -1.3.1.76 * priestia megaterium 0.06 0.06 1 PMID:12408752 -1.3.1.76 * saccharomyces cerevisiae 0.0112 0.0112 1 PMID:11980703 -1.3.1.76 * salmonella enterica 0.00993 0.00993 1 PMID:14595395 -1.3.1.76 * staphylococcus aureus 0.062 0.062 1 PMID:31605669 -1.3.1.78 * acinetobacter calcoaceticus 0.0043 0.0040999999999999995 2 PMID:4074072 -1.3.1.78 * acinetobacter lwoffii 0.0063 0.0063 1 PMID:4074072 -1.3.1.78 * acinetobacter sp. 0.0021 0.0021 1 PMID:4074072 -1.3.1.78 * anabaena sp. 0.0078 0.0078 1 PMID:15171683 -1.3.1.78 * arabidopsis thaliana 142.0 107.5 2 PMID:12354106 -1.3.1.78 * chlorella sorokiniana 0.0024 0.0024 1 PMID:15171683 -1.3.1.78 * fischerella sp. 0.0109 0.0109 1 PMID:15171683 -1.3.1.78 * nicotiana sylvestris 0.0011 0.0011 1 * -1.3.1.78 * porphyridium purpureum 0.0097 0.0097 1 PMID:15171683 -1.3.1.78 * prochlorothrix hollandica 0.0024 0.0024 1 PMID:15171683 -1.3.1.78 * sorghum bicolor 0.43 0.43 1 PMID:2939643 -1.3.1.78 * synechococcus elongatus pcc 6301 0.0115 0.0115 1 PMID:15171683 -1.3.1.78 * synechocystis sp. 88.1 44.057249999999996 2 PMID:15171683;PMID:16615917 -1.3.1.78 * synechocystis sp. pcc 6803 220.0 220.0 1 PMID:15171683 -1.3.1.8 * bos taurus 1.46 0.645 6 PMID:3994691;PMID:468815 -1.3.1.8 * mus musculus 0.00065 0.00065 1 PMID:10505644 -1.3.1.8 * mycolicibacterium smegmatis 1.25 1.25 1 PMID:6501266 -1.3.1.8 * rattus norvegicus 1.54 0.04 3 PMID:3977322;PMID:4387390;PMID:4404888 -1.3.1.84 * cereibacter sphaeroides 130.0 130.0 1 PMID:23955006 -1.3.1.84 * escherichia coli 72.0 72.0 1 PMID:23955006 -1.3.1.84 * metallosphaera sedula 2.9 2.9 1 PMID:19429610 -1.3.1.84 * ruegeria pomeroyi 98.0 0.195 3 PMID:23815737;PMID:23955006 -1.3.1.84 * sulfurisphaera tokodaii 18.7 18.7 1 PMID:19429610 -1.3.1.86 * bos taurus 0.0501 0.0281 2 PMID:4149043 -1.3.1.86 * streptomyces collinus 3.316 0.1743 6 PMID:8521864;PMID:9636144 -1.3.1.9 * allium ampeloprasum 0.008 0.0058 2 PMID:16663268 -1.3.1.9 * bacillus subtilis 2.3 0.16 4 PMID:11007778 -1.3.1.9 * brassica napus 200.0 177.75 2 * -1.3.1.9 * carthamus tinctorius 0.0153 0.01069 2 PMID:7125663 -1.3.1.9 * persea americana 0.068 0.068 1 PMID:7075600 -1.3.1.9 * spinacia oleracea 63.69 63.69 1 PMID:6756317 -1.3.1.95 * anaerotignum propionicum 0.79 0.28 3 PMID:12603323;PMID:22810300 -1.3.1.95 * metallosphaera sedula 2.9 1.4569999999999999 2 PMID:19429610 -1.3.1.95 * sulfurisphaera tokodaii 18.7 11.649999999999999 2 PMID:19429610 -1.3.1.98 * enterobacter cloacae 1.84 0.9275 2 PMID:4394163;PMID:4717533 -1.3.1.98 * escherichia coli 31.4 17.36 2 PMID:36973;PMID:8448160 -1.3.2.3 * arabidopsis thaliana 76.0 41.5 2 PMID:18190525 -1.3.2.3 * brassica oleracea var. botrytis 50800.0 25401.5 2 PMID:9374475 -1.3.2.3 * cucumis sativus 0.028 0.025 2 * -1.3.2.3 * ipomoea batatas 37000.0 44.5 3 PMID:10050319;PMID:7775377 -1.3.2.3 * phaseolus vulgaris 0.0399 0.0399 1 PMID:10398727 -1.3.3.10 * chromobacterium violaceum 30.3 30.3 1 PMID:7559518 -1.3.3.10 * pseudomonas sp. 2.32 0.91 8 PMID:7263628 -1.3.3.12 * saccharomyces cerevisiae 3.448 2.104 2 PMID:369458;PMID:6754380 -1.3.3.12 * trypanosoma cruzi 1.19 1.19 1 PMID:21397737 -1.3.3.14 * streptomyces galilaeus 952.0 952.0 1 PMID:528393 -1.3.3.3 * bos taurus 0.72 0.7 3 PMID:7372605;PMID:8407975;PMID:9251001 -1.3.3.3 * escherichia coli 37.5 37.5 1 PMID:13129604 -1.3.3.3 * glycine max 117.5 117.5 1 * -1.3.3.3 * homo sapiens 0.26 0.0051 5 PMID:17179900;PMID:8955072;PMID:9074788 -1.3.3.3 * mus musculus 0.3 0.28 3 PMID:2540974;PMID:8547339;PMID:9251001 -1.3.3.3 * nicotiana tabacum 0.002 0.002 1 PMID:4986869 -1.3.3.3 * rattus sp. 0.375 0.192 2 PMID:11079369;PMID:5881662 -1.3.3.3 * saccharomyces cerevisiae 0.08483 0.00925 3 PMID:4153629;PMID:9251002 -1.3.3.4 * bos taurus 0.0001 0.0001 1 PMID:2439126 -1.3.3.4 * bradyrhizobium japonicum 3e-05 3e-05 1 * -1.3.3.4 * homo sapiens 7.15 3.57615 2 PMID:11929051;PMID:12922165 -1.3.3.4 * hordeum vulgare 0.015 0.0135 2 PMID:3663113 -1.3.3.4 * megalodesulfovibrio gigas 0.012 0.012 1 PMID:3667528 -1.3.3.4 * mus musculus 0.038 0.01900035835 2 PMID:16039600;PMID:3606986 -1.3.3.4 * nicotiana tabacum 4.27 4.27 1 PMID:17134376 -1.3.3.4 * rattus norvegicus 0.0087 0.00465 2 PMID:3663105;PMID:6461 -1.3.3.4 * saccharomyces cerevisiae 0.73 0.67 3 PMID:234450;PMID:7798202;PMID:8621563 -1.3.3.4 * spinacia oleracea 0.14 0.14 1 PMID:10965946 -1.3.3.5 * albifimbria verrucaria 214.3 24.0 13 PMID:10074356;PMID:15802224;PMID:15865445;PMID:17020746;PMID:18445482;PMID:19907083;PMID:20852807;PMID:22862914;PMID:29491248 -1.3.3.5 * rattus norvegicus 0.00157 0.0010400000000000001 2 PMID:3790083;PMID:3814617 -1.3.3.5 * trachydermella tsunodae 500.0 500.0 1 PMID:17020746 -1.3.3.6 * beauveria bassiana 0.0108 0.006645 8 PMID:17139608 -1.3.3.6 * candida tropicalis 58.0 19.13 3 PMID:518611;PMID:6639056 -1.3.3.6 * cucumis sativus 27.0 27.0 1 PMID:3087978 -1.3.3.6 * glutamicibacter nicotianae 77.14 77.14 1 * -1.3.3.6 * homo sapiens 1.6e-05 1.6e-05 1 PMID:20185470 -1.3.3.6 * paenarthrobacter ureafaciens 60.9 31.3 4 PMID:17141592 -1.3.3.6 * rattus norvegicus 27.2 1.5 7 PMID:15477094;PMID:28077576;PMID:697834;PMID:7400120;PMID:7417271 -1.3.3.6 * yarrowia lipolytica 19.7 10.825 2 PMID:11147819;PMID:12392712 -1.3.3.6 * zea mays 5.3 2.8375 2 PMID:8973574 -1.3.3.7 * rhodotorula glutinis 9.25 9.25 1 * -1.3.5.1 * ascaris suum 28.9 1.62 8 PMID:2843227;PMID:3753651;PMID:7822332 -1.3.5.1 * bacillus cereus 0.0076 0.0076 2 PMID:18535631 -1.3.5.1 * bacillus licheniformis 6.1 6.1 1 PMID:17154542 -1.3.5.1 * bos taurus 56.0 28.5 4 PMID:2843227;PMID:2994719;PMID:9785479 -1.3.5.1 * corynebacterium glutamicum 57.5 57.5 1 PMID:15883782 -1.3.5.1 * escherichia coli 509.0 264.0 3 PMID:3078445;PMID:383238;PMID:9092498 -1.3.5.1 * homo sapiens 0.039 0.0315 2 PMID:14623340 -1.3.5.1 * ictidomys tridecemlineatus 0.05 0.05 1 PMID:20112024 -1.3.5.1 * mammalia 67.0 67.0 1 PMID:713837 -1.3.5.1 * mycolicibacterium phlei 19.0 19.0 1 PMID:3722123 -1.3.5.1 * paracoccus denitrificans 0.01 0.01 1 * -1.3.5.1 * rattus norvegicus 0.154 0.026 3 PMID:20143725;PMID:2843227 -1.3.5.1 * sulfolobus acidocaldarius 7.5 7.5 1 PMID:1935955 -1.3.5.1 * wolinella succinogenes 140.0 140.0 1 PMID:7397125 -1.3.5.2 * bos taurus 103.0 51.5033 2 PMID:3733756;PMID:8852433 -1.3.5.2 * candida albicans 6.0 6.0 1 PMID:16774642 -1.3.5.2 * cavia porcellus 0.0026 0.0026 1 PMID:8852433 -1.3.5.2 * drosophila melanogaster 9.6 9.6 1 PMID:12213251 -1.3.5.2 * eimeria tenella 0.0017 0.0017 1 PMID:30626105 -1.3.5.2 * escherichia coli 22.0 7.4 7 PMID:10074342;PMID:211391 -1.3.5.2 * homo sapiens 150.0 96.5 6 PMID:11248707;PMID:17369345;PMID:31997699;PMID:7487077;PMID:9693067 -1.3.5.2 * lactococcus lactis 22.0 8.25 6 PMID:10074342 -1.3.5.2 * mus musculus 101.0 50.5075 2 PMID:11248707;PMID:8852433 -1.3.5.2 * neurospora crassa 15.0 15.0 1 PMID:211392 -1.3.5.2 * plasmodium falciparum 0.0002672 0.0002672 1 PMID:7727509 -1.3.5.2 * rattus norvegicus 130.0 125.0 5 PMID:11248707;PMID:8852433;PMID:9693067 -1.3.5.2 * sus scrofa 0.0078 0.0054 3 PMID:8852433 -1.3.5.2 * toxoplasma gondii 84.0 84.0 1 PMID:22580100 -1.3.5.2 * trypanosoma cruzi 548000.0 245000.0 3 PMID:12106873 -1.3.5.3 * escherichia coli 4.2e-06 4.2e-06 1 PMID:20484676 -1.3.7.1 * clostridium sp. 1.9 1.9 1 PMID:5767303 -1.3.7.1 * eubacterium barkeri 350.0 350.0 1 PMID:16894175 -1.3.7.4 * cucumis sativus 1.1e-06 7.5e-07 2 PMID:1939244 -1.3.7.7 * rhodobacter capsulatus 0.05 0.0262 3 PMID:18358835;PMID:20400946 -1.3.7.8 * desulfosarcina cetonica 26.0 26.0 1 PMID:31430028 -1.3.7.8 * pseudomonas sp. 0.01 0.01 1 PMID:1555579 -1.3.7.8 * thauera aromatica 0.55 0.25 3 PMID:18826310;PMID:29769313;PMID:8575453 -1.3.7.8 * thauera chlorobenzoica 0.212 0.0275 10 PMID:22010634;PMID:29769313 -1.3.8.1 * bos taurus 17.9 1.42 3 PMID:13130521;PMID:6546382 -1.3.8.1 * clostridium acetobutylicum 3.3 1.2 3 PMID:8655474;PMID:9009069 -1.3.8.1 * clostridium kluyveri 170.0 170.0 1 PMID:4063066 -1.3.8.1 * dasytricha ruminantium 0.003 0.003 1 PMID:3924032 -1.3.8.1 * eubacterium oxidoreducens 0.871 0.8155 2 PMID:3571153 -1.3.8.1 * homo sapiens 7.4 6.65 2 PMID:12220177;PMID:3597357 -1.3.8.1 * mus musculus 0.0329 0.0329 1 PMID:18500942 -1.3.8.1 * oryctolagus cuniculus 0.48 0.48 1 PMID:1247597 -1.3.8.1 * pseudomonas putida 0.86 0.47 3 PMID:16024185 -1.3.8.1 * rattus norvegicus 10.6 0.0835 10 PMID:2574596;PMID:3663132;PMID:3968063;PMID:4084576;PMID:7334008;PMID:8952487 -1.3.8.1 * syntrophomonas wolfei 0.19 0.12 3 * -1.3.8.10 * geobacter metallireducens 2.3 1.65 2 PMID:25112478 -1.3.8.10 * syntrophus aciditrophicus 9.5 5.8 2 PMID:23667239 -1.3.8.11 * geobacter metallireducens 29.0 29.0 1 PMID:25112478 -1.3.8.11 * syntrophus aciditrophicus 52.0 27.05 2 PMID:23667239 -1.3.8.13 * escherichia coli 233.0 233.0 1 PMID:10209289 -1.3.8.13 * proteus sp. (in: enterobacteria) 6.35 6.35 1 PMID:15731894 -1.3.8.2 * staphylococcus aureus 0.005 0.005 1 PMID:10498735 -1.3.8.3 * geobacter metallireducens 4.4 4.4 1 PMID:31405915 -1.3.8.3 * thauera aromatica 7.0 6.7 2 PMID:12420174;PMID:31405915 -1.3.8.4 * cavia porcellus 0.172 0.043 9 PMID:7007368 -1.3.8.4 * homo sapiens 11.7 0.17 29 PMID:10713113;PMID:15574432;PMID:3597357;PMID:6928646;PMID:7640268;PMID:9665741 -1.3.8.4 * lathyrus oleraceus 0.3 0.16499999999999998 2 PMID:10913142 -1.3.8.4 * rattus norvegicus 2.68 0.012 11 PMID:2853821;PMID:7007368 -1.3.8.4 * solanum tuberosum 1.0 1.0 1 PMID:11231285 -1.3.8.5 * ascaris suum 1.62 1.6 2 PMID:3988734 -1.3.8.5 * homo sapiens 28.0 28.0 1 PMID:12855692 -1.3.8.5 * rattus norvegicus 35.0 2.476 3 PMID:12855692;PMID:2853820 -1.3.8.6 * azoarcus sp. 0.216 0.1795 4 PMID:18177371 -1.3.8.6 * homo sapiens 2224.0 106.2 4 PMID:12948740;PMID:3081514;PMID:31491587 -1.3.8.6 * sus scrofa 2.3 2.3 1 PMID:3081514 -1.3.8.7 * aspergillus niger 0.08 0.08 1 PMID:10206707 -1.3.8.7 * bos taurus 0.272 0.168 3 PMID:1015826 -1.3.8.7 * caulobacter vibrioides 0.043 0.0235 2 PMID:2875991 -1.3.8.7 * homo sapiens 24.9 6.75 3 PMID:3597357;PMID:7578106;PMID:9208949 -1.3.8.7 * rattus norvegicus 11.9 10.0 7 PMID:15358373;PMID:3968063;PMID:4084576;PMID:7278659;PMID:7334008 -1.3.8.7 * sus scrofa 4.0 4.0 1 PMID:15358373;PMID:7278659 -1.3.8.8 * bos taurus 32.5 0.259 5 PMID:1015826;PMID:6546382 -1.3.8.8 * escherichia coli 0.0055 0.000965 8 PMID:2895101 -1.3.8.8 * homo sapiens 15.27 0.27 7 PMID:19649258;PMID:9182995;PMID:9487154 -1.3.8.8 * mus musculus 0.2546 0.15748499999999999 2 PMID:18720429 -1.3.8.8 * rattus norvegicus 2.1 1.015 20 PMID:3968063;PMID:3968065;PMID:7334008 -1.3.98.1 * crithidia fasciculata 3.99 3.99 1 PMID:6299333 -1.3.98.1 * lactobacillus delbrueckii subsp. bulgaricus 117.5 117.5 1 PMID:5547979 -1.3.98.1 * lactococcus lactis 17.0 14.7 4 PMID:12732650;PMID:8732756 -1.3.98.1 * leishmania major 3.12 3.12 1 PMID:16600626 -1.3.98.1 * neobodo saliens 3.318 2.1525 2 PMID:17475213 -1.3.98.1 * pseudomonas sp. 0.032 0.032 1 PMID:4380263 -1.3.98.1 * rattus norvegicus 0.072 0.072 1 PMID:199900 -1.3.98.1 * saccharolobus solfataricus 3948.0 3948.0 1 PMID:12072960 -1.3.98.1 * saccharomyces cerevisiae 5.1 1.375 4 PMID:17617217 -1.3.98.1 * trypanosoma brucei brucei 1.4 1.015 2 PMID:6299333 -1.3.98.1 * trypanosoma cruzi 151000.0 2.2800000000000002 4 PMID:12106873 -1.3.99.14 * pseudomonas sp. 0.7 0.7 1 * -1.3.99.16 * brevundimonas diminuta 13.87 13.87 1 PMID:8157655 -1.3.99.17 * comamonas testosteroni 4.8 0.1505 4 PMID:10427712;PMID:7556204 -1.3.99.17 * pseudomonas putida 22.0 17.6 2 PMID:15902470;PMID:2090161 -1.3.99.17 * rhodococcus sp. (in: high g+c gram-positive bacteria) 5.8 5.8 1 PMID:1789933 -1.3.99.18 * pseudomonas sp. 7.82 7.82 1 PMID:8292263 -1.3.99.18 * serratia marcescens 64.5 64.5 1 PMID:8357532 -1.3.99.19 * agrobacterium sp. 3.3 3.3 1 PMID:1418685 -1.3.99.28 * rhodobacter capsulatus 0.00029 0.00029 1 PMID:8830054 -1.3.99.29 * chromochloris zofingiensis 0.0004 0.0004 1 PMID:20221629 -1.3.99.4 * gordonia rubripertincta 113.0 113.0 1 PMID:2317517 -1.3.99.4 * mycolicibacterium neoaurum 12781.5 2623.11 13 PMID:20453136;PMID:23298646;PMID:26886757;PMID:31289904 -1.3.99.4 * pimelobacter simplex 109200.0 59200.0 15 PMID:17451526;PMID:32786835 -1.3.99.4 * rhodococcus erythropolis 72.9 72.9 1 PMID:24165124 -1.3.99.41 * ruegeria lacuscaerulensis 0.039 0.039 1 PMID:21562561 -1.3.99.41 * ruegeria pomeroyi 1.23 1.23 1 PMID:21562561 -1.3.99.6 * comamonas testosteroni 6.5 6.5 1 PMID:5907467 -1.3.99.8 * pseudomonas putida 0.09 0.09 1 PMID:16347977 -1.4.1.1 * alkalihalophilus pseudofirmus 15.0 15.0 1 PMID:29310857 -1.4.1.1 * anabaena cylindrica 38.0 38.0 1 PMID:4043 -1.4.1.1 * anabaena sp. 0.0051 0.0051 1 PMID:20675483 -1.4.1.1 * archaeoglobus fulgidus 203.0 131.5 2 PMID:12153329 -1.4.1.1 * bacillus licheniformis 19.0 19.0 1 PMID:4151305 -1.4.1.1 * bacillus subtilis 4.0 4.0 1 * -1.4.1.1 * bradyrhizobium japonicum 30.4 30.4 1 * -1.4.1.1 * desulfovibrio desulfuricans 0.564 0.564 1 PMID:4298732 -1.4.1.1 * geobacillus stearothermophilus 75.0 37.50545 2 PMID:17583806 -1.4.1.1 * halobacterium salinarum 178.0 173.0 2 PMID:486498;PMID:849265 -1.4.1.1 * helicobacter aurati 268.0 147.0 2 PMID:32534087 -1.4.1.1 * klebsiella aerogenes 92.0 92.0 1 PMID:9972262 -1.4.1.1 * lysinibacillus sphaericus 157.0 85.2 2 PMID:2390993;PMID:488097 -1.4.1.1 * phormidium lapideum 183.0 183.0 1 PMID:7896761 -1.4.1.1 * priestia megaterium 11.2 11.2 1 * -1.4.1.1 * propionibacterium freudenreichii 17.1 17.1 1 PMID:16347414 -1.4.1.1 * pseudomonas sp. 129.0 129.0 1 PMID:3446176 -1.4.1.1 * shewanella sp. 40.0 32.4 2 PMID:10473410;PMID:12664266 -1.4.1.1 * streptomyces phaeochromogenes 22.8 22.8 1 * -1.4.1.1 * vibrio proteolyticus 150.0 150.0 1 * -1.4.1.10 * mycobacterium tuberculosis 7.25 7.25 1 PMID:13948749 -1.4.1.11 * clostridium sp. 34.0 34.0 1 PMID:4344229 -1.4.1.12 * acetoanaerobium sticklandii 272.5 170.5 2 PMID:4394942;PMID:4684685 -1.4.1.13 * [brevibacterium] flavum 30.5 30.5 1 * -1.4.1.13 * amycolatopsis mediterranei 1.48 1.48 1 PMID:3350793 -1.4.1.13 * azospirillum brasilense 19.5 18.7 2 PMID:10785395;PMID:4019412 -1.4.1.13 * bacillus licheniformis 22.9 22.9 1 PMID:6501215 -1.4.1.13 * escherichia coli 26.2 13.33 7 PMID:3911003;PMID:4565085;PMID:6449;PMID:6450 -1.4.1.13 * gluconobacter oxydans 5.72 5.72 1 * -1.4.1.13 * klebsiella aerogenes 20.83 20.83 1 PMID:3911003 -1.4.1.13 * priestia megaterium 23.8 23.8 1 PMID:99144 -1.4.1.13 * pyrococcus sp. 1910.0 1910.0 1 PMID:9202379 -1.4.1.13 * rhodospirillum rubrum 21.0 21.0 1 PMID:1930133 -1.4.1.13 * sclerotinia sclerotiorum 7.6 7.6 1 * -1.4.1.13 * thiobacillus thioparus 9.3 9.3 1 PMID:14919 -1.4.1.14 * chlamydomonas reinhardtii 4.56 4.56 1 * -1.4.1.14 * clostridium pasteurianum 3.8 3.8 1 PMID:2611221 -1.4.1.14 * derxia gummosa 16.0 16.0 1 * -1.4.1.14 * lupinus angustifolius 18.0 18.0 1 PMID:21790 -1.4.1.14 * medicago sativa 13.1 13.1 1 PMID:16666762 -1.4.1.14 * neurospora crassa 4.76 4.76 1 PMID:6444511 -1.4.1.14 * oryza sativa 9.8 9.8 1 PMID:16668794 -1.4.1.14 * phaseolus vulgaris 8.05 5.925000000000001 2 PMID:16666475 -1.4.1.14 * prosthecochloris vibrioformis f. thiosulfatophilum 4.7 4.7 1 * -1.4.1.14 * saccharomyces cerevisiae 41.7 41.7 1 PMID:3911003 -1.4.1.14 * vicia faba 2.66 2.66 1 * -1.4.1.15 * agrobacterium tumefaciens 0.0739 0.07175 2 * -1.4.1.15 * alcaligenes faecalis 0.00069 0.00069 1 * -1.4.1.15 * candida albicans 0.0144 0.0144 1 PMID:1509828 -1.4.1.15 * corynebacterium ammoniagenes 0.00067 0.00067 1 * -1.4.1.15 * corynebacterium pseudodiphtheriticum 4e-05 4e-05 1 * -1.4.1.15 * hafnia alvei 0.00026 0.00026 1 * -1.4.1.15 * klebsiella aerogenes 0.0392 0.0052 3 * -1.4.1.15 * kocuria rosea 0.0001 0.0001 1 * -1.4.1.15 * lysinibacillus sphaericus 0.0029 0.0029 1 * -1.4.1.15 * micrococcus flavus 0.00021 0.00021 1 * -1.4.1.15 * morganella morganii 0.0016 0.0016 1 * -1.4.1.15 * pseudomonas fragi 5.9e-05 5.9e-05 1 * -1.4.1.15 * sinomonas atrocyanea 6.9e-05 6.9e-05 1 * -1.4.1.16 * brevibacterium sp. 131.0 131.0 1 * -1.4.1.16 * clostridium tetani 1.036 0.219 3 PMID:25754803 -1.4.1.16 * corynebacterium glutamicum 131.6 1.1900000000000002 6 PMID:3131636;PMID:3151991;PMID:8865347 -1.4.1.16 * lysinibacillus sphaericus 139.0 0.26849999999999996 8 PMID:10904 -1.4.1.16 * numidum massiliense 701.0 701.0 1 PMID:32485072 -1.4.1.16 * paenibacillus macerans 0.12 0.12 1 * -1.4.1.16 * sporosarcina globispora 0.19 0.19 1 * -1.4.1.16 * sporosarcina pasteurii 0.53 0.53 1 * -1.4.1.16 * symbiobacterium thermophilum 0.07 0.07 1 PMID:23728814 -1.4.1.16 * thermosyntropha lipolytica 31.8 31.8 1 PMID:32599299 -1.4.1.16 * ureibacillus thermosphaericus 8.28 8.28 1 PMID:22117688 -1.4.1.17 * pseudomonas sp. 0.37 0.37 1 PMID:236301 -1.4.1.18 * agrobacterium tumefaciens 15.7 11.6 2 PMID:2768207 -1.4.1.18 * geobacillus stearothermophilus 7.8 7.0 2 PMID:14766574 -1.4.1.19 * lathyrus oleraceus 70.0 23.0 5 * -1.4.1.19 * neltuma juliflora 30.0 15.5 4 * -1.4.1.19 * nicotiana tabacum 1.59 1.24 5 * -1.4.1.19 * solanum lycopersicum 39.0 33.5 2 * -1.4.1.19 * spinacia oleracea 0.648 0.0257 4 * -1.4.1.19 * zea mays 64.0 54.5 2 * -1.4.1.2 * [clostridium] symbiosum 58.0 29.245 2 PMID:19425107 -1.4.1.2 * agaricus bisporus 1.8 1.8 1 PMID:10323225 -1.4.1.2 * alicyclobacillus acidocaldarius 80.0 80.0 1 * -1.4.1.2 * amphibacillus xylanus 822.0 822.0 1 PMID:8836445 -1.4.1.2 * aspergillus nidulans 69.8 69.8 1 PMID:2524418 -1.4.1.2 * bacillus cereus 286.4 286.4 1 PMID:8515235 -1.4.1.2 * bacillus subtilis 440.0 440.0 1 PMID:16195607 -1.4.1.2 * bacteroides fragilis 183.0 183.0 1 * -1.4.1.2 * benjaminiella poitrasii 48.7 48.7 1 PMID:23588417 -1.4.1.2 * bos taurus 167.0 135.5 2 PMID:7588764 -1.4.1.2 * chlorella sorokiniana 200.0 200.0 1 PMID:16660436 -1.4.1.2 * clostridioides difficile 146.0 146.0 1 PMID:8424683 -1.4.1.2 * clostridium botulinum 1092.0 1092.0 1 PMID:3061371 -1.4.1.2 * cucurbita pepo 31.4 31.4 1 * -1.4.1.2 * entodinium caudatum 0.97 0.66 4 PMID:15921862 -1.4.1.2 * halobacterium salinarum 35.0 20.759999999999998 2 PMID:22527040 -1.4.1.2 * haloferax mediterranei 104.0 96.65 2 PMID:16200391 -1.4.1.2 * janthinobacterium lividum 3.1 1.86 2 PMID:17526698 -1.4.1.2 * lathyrus oleraceus 401.0 227.5 2 PMID:20057;PMID:7385942 -1.4.1.2 * lemna minor 540.0 540.0 1 PMID:7385942 -1.4.1.2 * medicago sativa 54.0 46.0 2 PMID:7405365 -1.4.1.2 * myriophyllum spicatum 0.0495 0.0495 1 PMID:32182513 -1.4.1.2 * peptoniphilus asaccharolyticus 174.0 9.8 11 PMID:17850332;PMID:4338318 -1.4.1.2 * phaseolus vulgaris 328.2 62.599999999999994 16 PMID:16187535 -1.4.1.2 * psychrobacter sp. 248.0 248.0 1 PMID:11867281 -1.4.1.2 * pyrobaculum islandicum 3.65 3.54 3 PMID:16285734 -1.4.1.2 * pyrococcus sp. 7.6 7.6 1 * -1.4.1.2 * rattus norvegicus 0.84 0.57 3 PMID:16155414 -1.4.1.2 * streptomyces clavuligerus 21.2 21.2 1 PMID:10924516 -1.4.1.2 * thermus thermophilus 70.0 70.0 1 * -1.4.1.2 * vitis vinifera 441.0 441.0 1 * -1.4.1.20 * dietzia maris 65.2 65.2 1 PMID:2536657 -1.4.1.20 * halalkalibacterium halodurans 26.6 15.100000000000001 2 PMID:29740797 -1.4.1.20 * lysinibacillus sphaericus 285.4 198.2 2 PMID:3112142 -1.4.1.20 * microbacterium sp. 37.1 37.1 1 PMID:9477256 -1.4.1.20 * pseudobacillus badius 4231.0 553.6 5 PMID:19495799;PMID:3311741 -1.4.1.20 * sporosarcina ureae 87.9 48.5 2 PMID:20658209;PMID:3112142 -1.4.1.21 * archaeoglobus fulgidus 4.6 4.6 2 PMID:16731057;PMID:22120624 -1.4.1.21 * bradyrhizobium japonicum 4.2 4.2 1 * -1.4.1.21 * bradyrhizobium lupini 0.75 0.75 1 * -1.4.1.21 * cupriavidus necator 137.0 137.0 2 PMID:21821928;PMID:22120624 -1.4.1.21 * delftia sp. cs1-4 32.8 18.95 2 PMID:28801651 -1.4.1.21 * klebsiella pneumoniae 26.5 1.7325 4 PMID:22120624;PMID:28801651;PMID:9819709 -1.4.1.21 * pseudomonas aeruginosa 147.0 127.0 3 PMID:21468714;PMID:22120624 -1.4.1.21 * rhodopseudomonas palustris 3.1 3.1 1 * -1.4.1.21 * thermotoga maritima 12.32 6.435 4 PMID:12496312 -1.4.1.23 * streptomyces coelicolor 19.0 16.5 2 PMID:2324704 -1.4.1.26 * fervidobacterium nodosum 92.0 46.5 2 PMID:24326351 -1.4.1.27 * synechocystis sp. pcc 6803 14.0 14.0 1 PMID:32311173 -1.4.1.28 * cystobacter fuscus 955.0 60.2 25 * -1.4.1.28 * laribacter hongkongensis 364.0 267.0 2 * -1.4.1.28 * microbacterium sp. ma1 851.3 165.55 26 * -1.4.1.28 * mycolicibacterium smegmatis 196.2 31.2 28 * -1.4.1.28 * petrotoga mobilis 51.9 28.75 2 * -1.4.1.3 * anguilla anguilla 7.53 7.53 1 PMID:1639763 -1.4.1.3 * azospirillum brasilense 41.9 41.9 1 PMID:3956501 -1.4.1.3 * bacillus subtilis 47.0 47.0 1 PMID:14949 -1.4.1.3 * bacteroides fragilis 32.3 5.9 5 PMID:3667555 -1.4.1.3 * bacteroides ovatus 2.22 0.597 4 * -1.4.1.3 * bos taurus 40.0 4.8 5 PMID:3986210;PMID:4600141 -1.4.1.3 * cereibacter sphaeroides 13.0 8.5 2 * -1.4.1.3 * chlamydomonas reinhardtii 230.0 67.0 3 PMID:1540636 -1.4.1.3 * glycine max 1.8 1.5 2 PMID:7197901 -1.4.1.3 * homo sapiens 161.9 144.55 4 PMID:11903050;PMID:17253646 -1.4.1.3 * lemna minor 3.5 1.93 2 * -1.4.1.3 * parabacteroides distasonis 1.96 1.1085 2 * -1.4.1.3 * pyrococcus 17.0 17.0 1 PMID:9520268 -1.4.1.3 * pyrococcus furiosus 423.0 415.0 4 PMID:1576153;PMID:7887598 -1.4.1.3 * rattus norvegicus 185.0 33.35 4 PMID:10618641;PMID:11452377;PMID:3986210 -1.4.1.3 * saccharolobus solfataricus 423.0 83.0 3 PMID:10774743;PMID:1899341;PMID:1901040 -1.4.1.3 * sphagnum fallax 40.86 40.86 1 * -1.4.1.3 * sus scrofa 4.6 4.6 1 * -1.4.1.3 * tenebrio molitor 126.4 126.4 1 * -1.4.1.3 * thunnus thynnus 1.93 1.93 1 PMID:182270 -1.4.1.3 * uncultured bacterium 79.4 79.4 1 PMID:22360886 -1.4.1.3 * urocitellus richardsonii 201.0 195.5 2 PMID:11235914 -1.4.1.4 * aeropyrum pernix 5.2 5.2 1 PMID:11139075 -1.4.1.4 * agaricus bisporus 8.2 8.2 1 PMID:7765894 -1.4.1.4 * aspergillus nidulans 7.0 3.685 2 PMID:15870451 -1.4.1.4 * aspergillus niger 631.0 59.4 3 PMID:15870451;PMID:25372818 -1.4.1.4 * bacillus sp. (in: firmicutes) 1140.0 778.0 2 * -1.4.1.4 * bifidobacterium adolescentis 0.7 0.7 1 * -1.4.1.4 * bifidobacterium bifidum 0.31 0.3 2 * -1.4.1.4 * bifidobacterium breve 1.1 0.8600000000000001 2 * -1.4.1.4 * bifidobacterium longum 0.59 0.52 2 * -1.4.1.4 * bifidobacterium longum subsp. infantis 1.16 0.98 2 * -1.4.1.4 * bifidobacterium pseudolongum 0.7 0.7 3 * -1.4.1.4 * bifidobacterium thermophilum 0.4 0.4 1 * -1.4.1.4 * bryopsis maxima 18.4 18.4 1 PMID:9190263 -1.4.1.4 * dictyostelium discoideum 121.0 121.0 1 PMID:1656203 -1.4.1.4 * escherichia coli 250.0 47.25 8 PMID:18294195;PMID:19425107;PMID:235298;PMID:241744 -1.4.1.4 * geotrichum candidum 3802.7 3802.7 1 PMID:28050850 -1.4.1.4 * giardia duodenalis 930.0 930.0 1 PMID:9538867 -1.4.1.4 * haloferax mediterranei 60.0 60.0 2 PMID:9064251 -1.4.1.4 * klebsiella pneumoniae 190.0 190.0 1 PMID:16233253 -1.4.1.4 * lactiplantibacillus plantarum 5.64 5.64 1 PMID:20662973 -1.4.1.4 * leptolyngbya laminosa 32.9 32.9 1 PMID:3139639 -1.4.1.4 * limosilactobacillus fermentum 57.6 57.6 1 * -1.4.1.4 * metabacillus fastidiosus 388.0 388.0 1 PMID:2543290 -1.4.1.4 * mycolicibacterium smegmatis 80.2 80.2 1 PMID:7417453 -1.4.1.4 * myriophyllum spicatum 0.029 0.029 1 PMID:32182513 -1.4.1.4 * nitrobacter hamburgensis 9.2 9.2 1 * -1.4.1.4 * plasmodium falciparum 74.5 28.0 5 PMID:22342964;PMID:8631352 -1.4.1.4 * proteus inconstans 231.0 231.0 1 * -1.4.1.4 * psychrobacter sp. 204.1 141.05 2 PMID:10601858 -1.4.1.4 * pyrococcus furiosus 10.3 10.3 1 PMID:7763882 -1.4.1.4 * pyrococcus woesei 24.3 24.3 1 PMID:7763882 -1.4.1.4 * saccharomyces cerevisiae 2.54 2.54 1 PMID:4126 -1.4.1.4 * salmonella enterica subsp. enterica serovar typhimurium 214.0 214.0 1 PMID:4144744 -1.4.1.4 * streptomyces fradiae 10.92 6.3 2 PMID:2561488 -1.4.1.4 * symbiobacterium toebii 32.8 32.8 1 * -1.4.1.4 * thermococcus kodakarensis 2500.0 2500.0 1 PMID:9704028 -1.4.1.4 * thermococcus litoralis 194.3 139.65 2 PMID:11265468;PMID:8135516 -1.4.1.4 * thermococcus sp. 2940.0 1702.0 2 PMID:8399386 -1.4.1.4 * thermococcus waiotapuensis 160.0 160.0 1 PMID:12013436 -1.4.1.4 * thermophilic bacillus 46.2 46.2 1 PMID:238942 -1.4.1.4 * thermotoga maritima 2.5 2.5 1 PMID:10366510 -1.4.1.4 * trichomonas vaginalis 133.0 133.0 1 PMID:2901980 -1.4.1.4 * trypanosoma cruzi 51.2 51.2 1 PMID:27404 -1.4.1.5 * citrobacter sp. 1.59 1.145 2 PMID:18051956 -1.4.1.5 * proteus sp. (in: enterobacteria) 1.2 0.965 2 PMID:18051956 -1.4.1.5 * pseudomonas sp. 0.47 0.47 1 PMID:18051956 -1.4.1.8 * kitasatospora aureofaciens 366.5 64.31 3 PMID:7669808 -1.4.1.8 * priestia megaterium 7.8 7.8 1 * -1.4.1.8 * streptomyces albus 302.4 36.585 12 PMID:10612726;PMID:11386345 -1.4.1.8 * streptomyces coelicolor 19.0 3.8 5 PMID:2324704 -1.4.1.8 * streptomyces fradiae 40.92 30.240000000000002 2 * -1.4.1.8 * streptomyces virginiae 19.6 19.6 1 PMID:2803248 -1.4.1.9 * alloalcanivorax dieselolei 0.88 0.88 1 * -1.4.1.9 * bacillus cereus 57.0 29.8 2 PMID:28000046 -1.4.1.9 * bacillus sp. (in: firmicutes) 110.0 110.0 1 * -1.4.1.9 * bacillus subtilis 15.23 15.23 1 PMID:3149392 -1.4.1.9 * citrobacter freundii 320.0 320.0 1 PMID:24475337 -1.4.1.9 * geobacillus stearothermophilus 120.0 116.0 2 PMID:2503013;PMID:3069133 -1.4.1.9 * heyndrickxia coagulans 1338.0 1338.0 1 * -1.4.1.9 * laceyella sacchari 327.0 167.5 4 PMID:26861852 -1.4.1.9 * lysinibacillus sphaericus 71.7 12.19 5 PMID:18626578;PMID:670223 -1.4.1.9 * natrialba magadii 1.92 1.92 1 * -1.4.1.9 * neomoorella thermoacetica 115.0 115.0 1 * -1.4.1.9 * planifilum fimeticola 51.0 51.0 1 PMID:33859982 -1.4.1.9 * pseudoalteromonas sp. ant 178 275.0 275.0 1 PMID:30275355 -1.4.1.9 * roseibium aggregatum 15871.0 5394.5 6 * -1.4.1.9 * sporosarcina psychrophila 53.8 26.936999999999998 2 * -1.4.1.9 * thermoactinomyces intermedius 122.0 112.0 2 PMID:8020469 -1.4.2.1 * nitrobacter winogradskyi 13.1 13.1 1 PMID:5016640 -1.4.3.1 * bos taurus 29.1 25.3 3 PMID:10209293;PMID:3611051;PMID:7049247 -1.4.3.1 * caenorhabditis elegans 65.3 54.65 2 PMID:32376478 -1.4.3.1 * carassius langsdorfii 0.00119 0.000895 2 * -1.4.3.1 * cyprinus carpio 0.00076 0.00062 2 * -1.4.3.1 * homo sapiens 91.2 3.05 8 PMID:25747990 -1.4.3.1 * mus musculus 13.1 4.31 9 PMID:18235994;PMID:25747990;PMID:29292239 -1.4.3.1 * oncorhynchus mykiss 0.00233 0.00127 2 * -1.4.3.1 * oryctolagus cuniculus 2.4 2.4 1 PMID:6060479 -1.4.3.1 * pagrus major 0.00144 0.0013150000000000002 2 * -1.4.3.1 * rattus norvegicus 51.7 26.735000000000003 2 PMID:29292239 -1.4.3.1 * seriola quinqueradiata 0.00062 0.00055 3 * -1.4.3.1 * sus scrofa 62.0 0.4 3 PMID:17234685;PMID:236180 -1.4.3.1 * thermomyces dupontii 169.0 107.65 2 PMID:30937498 -1.4.3.1 * vanrija humicola 123.0 76.1 5 PMID:15115779;PMID:8645733 -1.4.3.10 * kocuria rosea 59.16 35.0 3 PMID:4341347;PMID:6621390 -1.4.3.11 * streptomyces hygroscopicus subsp. hygroscopicus 6.0 6.0 1 PMID:2737205 -1.4.3.11 * streptomyces sp. 55.1 55.1 1 * -1.4.3.12 * erythrobacteraceae bacterium 0.26 0.26 1 PMID:32203655 -1.4.3.12 * microbacterium oxydans 5.69 1.345 26 PMID:23793344 -1.4.3.12 * pseudomonas sp. 29.6 29.6 1 PMID:18451 -1.4.3.13 * bos taurus 1.2 1.2 1 PMID:12450117 -1.4.3.13 * homo sapiens 1.2 0.255 8 PMID:14550642;PMID:18566459;PMID:20600936 -1.4.3.14 * trichoderma cf. aureoviride 90.0 45.145 2 PMID:23234070 -1.4.3.14 * trichoderma pseudokoningii 61.3 61.3 1 * -1.4.3.14 * trichoderma viride 90.0 66.125 4 PMID:32894626;PMID:6101334 -1.4.3.16 * pyrococcus horikoshii 3.2 3.2 1 PMID:12215812 -1.4.3.16 * thermococcus litoralis 3.86 3.86 1 PMID:29143132 -1.4.3.19 * bacillus subtilis 1000.0 1.13 8 PMID:11874460;PMID:16739945 -1.4.3.19 * geobacillus kaustophilus 11.85 6.8 2 PMID:17894345 -1.4.3.2 * agkistrodon laticinctus 868.0 590.0 9 PMID:10441379 -1.4.3.2 * bothrops atrox 87.5 87.5 1 PMID:18804547 -1.4.3.2 * bothrops moojeni 665.0 330.0 16 PMID:17320169 -1.4.3.2 * bothrops pauloensis 580.0 337.5 10 PMID:19135502 -1.4.3.2 * bothrops pirajai 765.0 510.0 8 PMID:16809041 -1.4.3.2 * calloselasma rhodostoma 3.15 1.5799999999999998 2 PMID:17127077 -1.4.3.2 * chlamydomonas reinhardtii 39.5 18.1 24 PMID:8344302 -1.4.3.2 * coprinopsis cinerea 6.04 6.04 1 * -1.4.3.2 * crotalus durissus terrificus 5.44 5.44 1 PMID:31078582 -1.4.3.2 * daboia russelii russelii 8.96 7.950000000000001 2 PMID:18384385 -1.4.3.2 * gloydius ussuriensis 79.92 9.0 3 PMID:17854853;PMID:20100538 -1.4.3.2 * hebeloma cylindrosporum 1020.0 20.0 3 PMID:32852125 -1.4.3.2 * macrovipera lebetinus 14.4 5.5 7 PMID:16828829 -1.4.3.2 * micrurus lemniscatus 800.0 800.0 1 PMID:31759013 -1.4.3.2 * naja oxiana 21.0 1.19 11 PMID:18294891 -1.4.3.2 * neurospora crassa 1.45 1.45 1 PMID:5052831 -1.4.3.2 * pseudomonas sp. 1.16 0.5814999999999999 2 PMID:22704811 -1.4.3.2 * rattus norvegicus 1.98 1.98 1 PMID:4962138 -1.4.3.2 * rhodococcus opacus 5.4 5.4 3 PMID:12699695 -1.4.3.2 * sebastes schlegelii 26.0 10.2 3 PMID:17140417;PMID:20728563 -1.4.3.2 * synechococcus elongatus pcc 7942 = fachb-805 120.0 120.0 1 PMID:6766743 -1.4.3.20 * marinomonas mediterranea 36.9 36.9 1 PMID:20599635 -1.4.3.21 * escherichia coli 11.0 11.0 1 PMID:11985492 -1.4.3.21 * lathyrus oleraceus 13.6 3.69 4 PMID:22258083 -1.4.3.21 * mycobacterium sp. 6.7 4.9 2 PMID:18400766 -1.4.3.21 * ogataea angusta 5.6 0.213 7 PMID:8011631 -1.4.3.21 * rattus norvegicus 0.00555 0.0012200000000000002 10 PMID:17142964;PMID:17385065 -1.4.3.21 * rhodococcus opacus 13.14 3.223 4 * -1.4.3.21 * sus scrofa 2.08 1.0925 2 PMID:2848544;PMID:6615797 -1.4.3.22 * arachis hypogaea 0.58 0.58 1 * -1.4.3.22 * aspergillus niger 45400.0 2.76 5 PMID:7727530;PMID:8620882 -1.4.3.22 * crystallibacter crystallopoietes 14.3 14.3 1 PMID:16233600 -1.4.3.22 * euphorbia characias 27.0 27.0 1 PMID:6814913 -1.4.3.22 * glycine max 263.0 263.0 1 PMID:8239662 -1.4.3.22 * homo sapiens 32.7 0.73 7 PMID:12072962;PMID:182134;PMID:23371442;PMID:409634;PMID:6403048 -1.4.3.22 * hyoscyamus niger 0.0326 0.0326 1 PMID:16667438 -1.4.3.22 * lathyrus cicera 70.0 60.4 2 PMID:14686927;PMID:2798365 -1.4.3.22 * lathyrus odoratus 48.61 48.61 1 * -1.4.3.22 * lathyrus oleraceus 79.6 64.86 4 PMID:16989933 -1.4.3.22 * lathyrus sativus 64.25 64.25 1 * -1.4.3.22 * lens culinaris 100.0 85.4 2 PMID:8845363 -1.4.3.22 * onobrychis viciifolia 135.0 67.706 2 * -1.4.3.22 * oryza sativa 0.0166 0.0166 1 * -1.4.3.22 * papaver somniferum 12.0 12.0 1 * -1.4.3.22 * phaseolus vulgaris 6.7 6.7 1 PMID:2798365 -1.4.3.22 * rattus norvegicus 0.00226 0.00074 5 PMID:17142964 -1.4.3.22 * seriola quinqueradiata 21.1 21.1 1 * -1.4.3.22 * sus scrofa 3.2 0.263 14 PMID:11945979;PMID:2498301;PMID:4964016;PMID:6403525;PMID:826412 -1.4.3.22 * trifolium subterraneum 66.0 66.0 1 * -1.4.3.22 * triticum aestivum 0.023 0.023 1 * -1.4.3.22 * vicia faba 21.6 21.6 1 * -1.4.3.25 * synechococcus elongatus pcc 7942 = fachb-805 120.3 120.3 1 PMID:6766743 -1.4.3.3 * [candida] boidinii 139.0 139.0 1 PMID:11330678 -1.4.3.3 * candida tropicalis 5.0 5.0 1 * -1.4.3.3 * chlorella vulgaris 244.0 244.0 1 PMID:15607 -1.4.3.3 * cyprinus carpio 293.0 293.0 1 PMID:15694590 -1.4.3.3 * gallus gallus 0.014 0.0072250000000000005 2 PMID:17254537 -1.4.3.3 * glutamicibacter protophormiae 180.0 105.0 2 PMID:17279391 -1.4.3.3 * homo sapiens 80.0 18.0 3 PMID:17088322;PMID:19497370;PMID:31799256 -1.4.3.3 * neurospora crassa 0.5 0.5 1 PMID:13919 -1.4.3.3 * rasamsonia emersonii 112.0 91.0 2 PMID:31420577 -1.4.3.3 * rattus norvegicus 0.087 0.0082 5 PMID:17254537;PMID:18716858 -1.4.3.3 * rhodotorula toruloides 175.0 59.0 9 PMID:12354107;PMID:17145127;PMID:18330517;PMID:18594772;PMID:19066733;PMID:2565232 -1.4.3.3 * sus scrofa 8.8 4.949999999999999 4 PMID:17990314;PMID:7989339 -1.4.3.3 * trigonopsis variabilis 96.0 17.66 10 PMID:18330517;PMID:18594772;PMID:19909828;PMID:20193780;PMID:7905327;PMID:9771905 -1.4.3.3 * xenopus laevis 0.641 0.08925000000000001 4 PMID:23994361 -1.4.3.4 * aspergillus niger 0.13 0.13 1 PMID:30155214 -1.4.3.4 * avena sativa 0.02 0.010075 2 * -1.4.3.4 * danio rerio 0.243 0.243 1 PMID:18767136 -1.4.3.4 * homo sapiens 1.76 0.88625 2 PMID:11812236;PMID:851417 -1.4.3.4 * narcissus tazetta 1.365 0.6841 2 PMID:23924738 -1.4.3.4 * poecilia reticulata 0.162 0.162 1 PMID:18767136 -1.4.3.4 * rattus norvegicus 1.42 0.0011 24 PMID:17142964;PMID:18266289;PMID:19883764;PMID:708051;PMID:851417 -1.4.3.5 * agrobacterium tumefaciens 6.8e-05 6.8e-05 1 PMID:6319266 -1.4.3.5 * avena sativa 8.4e-05 8.4e-05 1 * -1.4.3.5 * brassica juncea 7.45e-05 7.45e-05 1 * -1.4.3.5 * brassica rapa 3.5e-05 3.5e-05 1 * -1.4.3.5 * chloridazon-degrading bacterium 2.5e-05 2.5e-05 1 PMID:6319266 -1.4.3.5 * daucus carota 1.2e-06 1.2e-06 1 * -1.4.3.5 * deinococcus radiodurans 8e-05 8e-05 1 PMID:6319266 -1.4.3.5 * escherichia coli 1.37 0.293 3 PMID:6319266;PMID:7860596;PMID:9693059 -1.4.3.5 * flavobacterium sp. 4e-05 4e-05 1 PMID:6319266 -1.4.3.5 * glebionis coronaria 1.3e-06 1.3e-06 1 * -1.4.3.5 * glycine max 1.2e-05 1.2e-05 1 * -1.4.3.5 * lactuca sativa 1e-06 1e-06 1 * -1.4.3.5 * medicago sativa 1.5e-06 1.5e-06 1 * -1.4.3.5 * oryctolagus cuniculus 0.432 0.3 5 PMID:13782387;PMID:3702680;PMID:440132;PMID:4711161 -1.4.3.5 * oryza sativa 7.3e-05 7.3e-05 1 * -1.4.3.5 * proteus mirabilis 7.3e-05 7.3e-05 1 PMID:6319266 -1.4.3.5 * pseudomonas chlororaphis subsp. aureofaciens 0.0005 0.0005 1 PMID:6319266 -1.4.3.5 * pseudomonas fluorescens 0.0007 0.0007 1 PMID:6319266 -1.4.3.5 * pseudomonas putida 0.000667 0.000667 1 PMID:6319266 -1.4.3.5 * pseudomonas sp. 0.000717 0.000717 1 PMID:6319266 -1.4.3.5 * raphanus sativus 3.66e-05 2.72e-05 2 * -1.4.3.5 * rattus norvegicus 1.708 0.15 3 PMID:2988502;PMID:6255956;PMID:6849871 -1.4.3.5 * rhodospirillum rubrum 2.2e-05 2.2e-05 1 PMID:6319266 -1.4.3.5 * saccharomyces cerevisiae 0.462 0.056 7 PMID:7896706 -1.4.3.5 * salmonella enterica subsp. enterica serovar typhimurium 4.2e-05 4.2e-05 1 PMID:6319266 -1.4.3.5 * serratia marcescens 6.5e-05 6.5e-05 1 PMID:6319266 -1.4.3.5 * spinacia oleracea 1.9e-05 1.9e-05 1 * -1.4.3.5 * sus scrofa 0.09 0.09 1 PMID:6697989 -1.4.3.5 * triticum aestivum 0.45 0.00012 16 PMID:7138019 -1.4.3.5 * vigna mungo 1.3e-06 1.3e-06 1 * -1.4.3.5 * vigna radiata var. radiata 6.2e-07 6.2e-07 1 * -1.4.3.5 * xanthomonas sp. 8.5e-05 8.5e-05 1 PMID:6319266 -1.4.3.7 * faxonius limosus 0.23 0.23 1 * -1.4.3.8 * phormia regina 0.00026 0.00026 1 PMID:4709585 -1.4.3.8 * pseudomonas sp. 0.0621 0.0621 1 PMID:14209947 -1.4.4.2 * arthrobacter globiformis 1.9 1.9 1 PMID:4414614 -1.4.4.2 * gallus gallus 4.13 4.13 1 PMID:7440562 -1.4.4.2 * lathyrus oleraceus 0.25 0.25 1 PMID:7625831 -1.4.4.2 * rattus norvegicus 1.045 0.5489999999999999 2 PMID:4460882;PMID:6778858 -1.4.4.2 * zea mays 0.02 0.02 1 PMID:17945380 -1.4.5.1 * escherichia coli b 6.8 6.8 1 PMID:6102989 -1.4.5.1 * helicobacter pylori 6.22 6.22 1 PMID:19212808 -1.4.5.1 * pseudomonas aeruginosa 0.653 0.653 1 PMID:3101751 -1.4.7.1 * bouvardia ternifolia 0.0045 0.0045 1 PMID:24249443 -1.4.7.1 * chlamydomonas reinhardtii 10.4 10.4 1 PMID:24254054 -1.4.7.1 * hordeum vulgare 4.2 1.592 4 PMID:9421934 -1.4.7.1 * hydrogenobacter thermophilus 1.5 0.6 3 PMID:17237175 -1.4.7.1 * oryza sativa 35.9 18.0025 4 PMID:10901618;PMID:16662307 -1.4.7.1 * pinus pinaster 8.16 8.16 1 PMID:7865781 -1.4.7.1 * spinacia oleracea 101.7 35.9 3 PMID:16662307;PMID:6746604 -1.4.7.1 * synechocystis sp. 36.6 36.6 1 PMID:10898944 -1.4.7.1 * vicia faba 7.0 7.0 1 PMID:892179 -1.4.7.1 * zea mays 0.077 0.077 1 * -1.4.9.1 * pseudomonas putida 4.67 4.67 1 PMID:26667 -1.4.9.1 * pseudomonas sp. 13.5 3.88 4 PMID:4388687;PMID:486505;PMID:5124384 -1.4.9.2 * achromobacter xylosoxidans 87.0 47.025 2 PMID:11495996;PMID:15388968 -1.4.9.2 * alcaligenes faecalis 95.0 14.3 5 PMID:11495996;PMID:16403029;PMID:3037269;PMID:6830237;PMID:8188594 -1.4.9.2 * pseudomonas putida 13.0 13.0 1 * -1.4.9.2 * pseudomonas sp. 9.11 9.11 1 PMID:3037269;PMID:6830237 -1.4.99.2 * bacteria 0.48 0.48 1 PMID:3657561;PMID:4724302 -1.4.99.2 * burkholderia sp. 0.02 0.02 1 PMID:15073291 -1.4.99.2 * paracoccus denitrificans 1.5 0.97 2 PMID:15073291 -1.4.99.2 * paracoccus pantotrophus 0.42 0.42 1 PMID:15073291 -1.4.99.2 * sinorhizobium meliloti 0.04 0.04 1 PMID:15073291 -1.4.99.6 * helicobacter pylori 6.22 0.16999999999999998 10 PMID:19212808 -1.4.99.6 * helicobacter pylori nctc 11637 = ccug 17874 = atcc 43504 = jcm 12093 6.22 1.77 4 PMID:19720515 -1.4.99.6 * pseudomonas fluorescens 0.213 0.163 2 * -1.5.1.1 * azospirillum brasilense 600.0 12.0 18 PMID:24649405 -1.5.1.1 * colwellia psychrerythraea 30.2 0.174 9 PMID:24649405 -1.5.1.1 * pseudomonas putida 92.0 3.4000000000000004 6 PMID:15561717 -1.5.1.10 * penicillium chrysogenum 22.0 11.022 2 PMID:11717275;PMID:14766586 -1.5.1.10 * saccharomyces cerevisiae 269.4 134.82 2 PMID:3098733 -1.5.1.11 * metridium senile 45.5 45.5 1 * -1.5.1.11 * mytilus galloprovincialis 324.8 10.1 7 PMID:21791249 -1.5.1.11 * pecten maximus 464.0 263.5 2 PMID:18028427 -1.5.1.15 * acetobacterium woodii 670.0 670.0 1 PMID:6608524 -1.5.1.15 * bos taurus 0.0002 0.0002 1 PMID:2275549 -1.5.1.15 * clostridium formicaceticum 1400.0 1400.0 1 PMID:4153026 -1.5.1.15 * cricetulus griseus 0.005 0.004 2 PMID:3877056 -1.5.1.15 * cricetus cricetus 0.0042 0.0042 1 PMID:3877056 -1.5.1.15 * homo sapiens 40.0 0.0047 29 PMID:16100107;PMID:2275549;PMID:3074630;PMID:3877056;PMID:9250981 -1.5.1.15 * mesocricetus auratus 0.00076 0.00076 1 PMID:3877056 -1.5.1.15 * methanosarcina barkeri 5.0 3.0 2 PMID:15349715 -1.5.1.15 * mus musculus 38.0 0.0060999999999999995 34 PMID:2275549;PMID:3074630;PMID:3487546;PMID:3877056;PMID:9250981 -1.5.1.15 * rattus norvegicus 0.0058 0.00145 10 PMID:2275549;PMID:3877056 -1.5.1.15 * saccharomyces cerevisiae 27.0 5.4 3 PMID:2223762;PMID:9250982 -1.5.1.15 * spodoptera frugiperda 43.0 43.0 1 PMID:9250981 -1.5.1.16 * nicotiana tabacum 1.045 1.045 1 PMID:21695 -1.5.1.17 * aphrodita aculeata 90.0 90.0 1 * -1.5.1.17 * littorina littorea 240.0 240.0 1 * -1.5.1.17 * magallana gigas 691.0 691.0 1 PMID:7238503 -1.5.1.18 * arthrobacter globiformis 0.61 0.61 1 PMID:7405363 -1.5.1.18 * arthrobacter sp. ts-15 64.02 34.36 2 PMID:31900306 -1.5.1.19 * helianthus annuus 26.34 26.34 1 PMID:476084 -1.5.1.2 * acetoanaerobium sticklandii 173.4 173.4 1 * -1.5.1.2 * bos taurus 7.1 5.6335 2 PMID:7115765 -1.5.1.2 * clostridium sporogenes 70.1 70.1 1 PMID:25881 -1.5.1.2 * cucurbita maxima 1.08 1.08 1 * -1.5.1.2 * cucurbita moschata 2070.0 2070.0 1 * -1.5.1.2 * escherichia coli 2550.0 784.625 4 PMID:11381339;PMID:12133;PMID:6296787 -1.5.1.2 * glycine max 60.0 60.0 1 * -1.5.1.2 * homo sapiens 32.0 14.0 5 PMID:16600630 -1.5.1.2 * hordeum vulgare 507.0 507.0 1 PMID:16664571 -1.5.1.2 * lathyrus oleraceus 0.042 0.042 1 PMID:16667072 -1.5.1.2 * mycobacterium tuberculosis 57.0 15.85 4 PMID:16199181 -1.5.1.2 * neurospora crassa 615.0 615.0 1 PMID:13630905 -1.5.1.2 * pseudomonas aeruginosa 3317.0 3317.0 1 PMID:114173 -1.5.1.2 * rattus norvegicus 720.0 389.95 2 PMID:3753884;PMID:4753151 -1.5.1.2 * saccharomyces cerevisiae 280.0 147.5 2 PMID:7004492;PMID:7011388 -1.5.1.2 * zymomonas mobilis subsp. mobilis 36.53 22.915 2 PMID:34331182 -1.5.1.20 * arabidopsis sp. 6.92 6.92 1 PMID:10593891 -1.5.1.20 * cercocebus sp. 0.00029 0.000255 2 PMID:3923481 -1.5.1.20 * clostridium formicaceticum 139.0 139.0 1 PMID:3517570;PMID:6381490 -1.5.1.20 * clostridium ljungdahlii 156.1 156.1 1 PMID:34255221 -1.5.1.20 * homo sapiens 12.4 0.413 3 PMID:11742092;PMID:12028998;PMID:2383427 -1.5.1.20 * rattus norvegicus 78.0 0.00071 5 PMID:1119805;PMID:3923481;PMID:4399897 -1.5.1.20 * saccharomyces cerevisiae 9.4e-05 9.4e-05 1 PMID:10600168 -1.5.1.20 * sus scrofa 153.0 0.00975 10 PMID:1186901;PMID:19474158;PMID:3702701;PMID:4399897;PMID:6967065 -1.5.1.21 * pseudomonas aeruginosa 42.3 7.04 6 PMID:24649405 -1.5.1.21 * pseudomonas putida 92.0 14.3 7 PMID:15561717;PMID:6801013;PMID:8234494 -1.5.1.21 * pseudomonas syringae 390.0 150.0 3 PMID:16192274 -1.5.1.22 * aphrodita aculeata 204.0 204.0 1 * -1.5.1.22 * marphysa sanguinea 87.0 44.8 2 * -1.5.1.22 * suberites domuncula 0.079 0.079 1 PMID:19454319 -1.5.1.23 * arabella iricolor 878.3 878.3 1 PMID:8840516 -1.5.1.23 * halichondria japonica 780.0 780.0 1 * -1.5.1.23 * haliotis tuberculata lamellosa 463.0 463.0 1 PMID:3769931 -1.5.1.23 * mazzaella japonica 25.0 25.0 1 * -1.5.1.23 * patiria pectinifera 551.8 551.8 1 PMID:10075484 -1.5.1.24 * clostridium botulinum 6.6 6.6 1 PMID:19933367 -1.5.1.24 * lactococcus lactis 40.5 40.5 1 PMID:2498334 -1.5.1.25 * bos taurus 16.6 16.6 1 PMID:3191146 -1.5.1.25 * sus scrofa 16.3 16.3 1 PMID:3371353 -1.5.1.26 * cellana grata 190.5 101.75 2 * -1.5.1.3 * bos taurus 103.0 27.845 4 PMID:1204646;PMID:4449452;PMID:45 -1.5.1.3 * burkholderia cepacia 10.4 7.995 2 PMID:2802552 -1.5.1.3 * candida albicans 250.0 250.0 1 PMID:2642898 -1.5.1.3 * cricetulus griseus 4.7 0.85 3 PMID:15711;PMID:9056490 -1.5.1.3 * crithidia fasciculata 6.8 6.8 1 * -1.5.1.3 * danio rerio 13.0 13.0 1 PMID:18056255 -1.5.1.3 * daucus carota 10.8 10.8 1 PMID:16453780 -1.5.1.3 * drosophila melanogaster 5.3 5.3 1 PMID:2116172 -1.5.1.3 * enterococcus faecium 300.0 300.0 6 PMID:5021603;PMID:5687716 -1.5.1.3 * escherichia coli 132.0 45.0 11 PMID:15299803;PMID:19054;PMID:2654934;PMID:4401227;PMID:46;PMID:9989225 -1.5.1.3 * gallus gallus 14.0 11.25 2 PMID:4449452 -1.5.1.3 * glycine max 156.3 56.5 3 PMID:3109322;PMID:820266 -1.5.1.3 * halalkalibacterium halodurans 138.4 122.9 3 PMID:17021659 -1.5.1.3 * heliothis virescens 20.8 20.8 1 PMID:10632709 -1.5.1.3 * homo sapiens 60.0 16.1 5 PMID:18056255;PMID:4396284;PMID:6838817 -1.5.1.3 * lacticaseibacillus casei 17.8 14.9 2 PMID:4217415 -1.5.1.3 * lactiplantibacillus plantarum 1.51 1.51 1 * -1.5.1.3 * lactobacillus leichmannii 200.0 200.0 1 PMID:10983423 -1.5.1.3 * leishmania major 8.0 6.4 3 PMID:8144647;PMID:9153248 -1.5.1.3 * mammalia 27.0 27.0 1 * -1.5.1.3 * methylorubrum extorquens 18.5 1.5855 4 PMID:30364315 -1.5.1.3 * mus musculus 50.0 11.3 8 PMID:19040;PMID:25980602;PMID:5018279 -1.5.1.3 * mycobacterium tuberculosis 15.5 15.5 1 PMID:15019741 -1.5.1.3 * plasmodium falciparum 17.0 8.91 2 PMID:17320089;PMID:9371090 -1.5.1.3 * plasmodium vivax 1.7 1.7 1 PMID:11295178 -1.5.1.3 * pneumocystis carinii 321.0 181.5 2 PMID:8425104 -1.5.1.3 * rattus norvegicus 28.0 0.009 3 PMID:25980602;PMID:7165835 -1.5.1.3 * saccharomyces cerevisiae 1.75 1.75 1 PMID:4403556 -1.5.1.3 * sus scrofa 36.0 35.9 2 PMID:500653 -1.5.1.3 * tetradesmus obliquus 15.8 15.8 1 PMID:3606123 -1.5.1.3 * thermotoga maritima 173.0 173.0 1 PMID:9738902 -1.5.1.3 * trypanosoma brucei 12.0 6.6 2 PMID:27175479;PMID:8538681 -1.5.1.30 * bacillus subtilis 85.5 52.5 3 PMID:19147107;PMID:9836433 -1.5.1.30 * entamoeba histolytica 22.0 22.0 1 PMID:6258069 -1.5.1.30 * homo sapiens 0.37 0.37 1 PMID:34598 -1.5.1.30 * rhodococcus erythropolis 133.0 127.5 2 PMID:11229908 -1.5.1.30 * streptomyces viridifaciens 141.0 124.0 2 PMID:9287340 -1.5.1.30 * vibrio harveyi 88.0 88.0 1 PMID:8206832 -1.5.1.32 * rauvolfia serpentina 0.0031 0.0030499999999999998 2 PMID:11937349 -1.5.1.33 * agrobacterium fabrum 9.83 5.03 3 PMID:32482721 -1.5.1.33 * trypanosoma brucei 2.3 1.05 4 PMID:16968221 -1.5.1.34 * badhamia polycephala 38.3 19.1845 2 PMID:12956422 -1.5.1.34 * bos taurus 70.7 0.972 5 PMID:16875;PMID:3037253;PMID:3600365;PMID:3711039;PMID:7174633 -1.5.1.34 * drosophila melanogaster 125.8 125.8 1 PMID:11004497 -1.5.1.34 * escherichia coli 20.7 20.7 1 PMID:3060113 -1.5.1.34 * homo sapiens 1180.0 318.0 8 PMID:2673215;PMID:3600366;PMID:3711039;PMID:4405600;PMID:6870900;PMID:7174633;PMID:7317032;PMID:8262916 -1.5.1.34 * ovis aries 610.0 312.8 2 PMID:3600367;PMID:3600388;PMID:4405600 -1.5.1.34 * pseudomonas sp. 33.2 33.2 1 PMID:8429 -1.5.1.34 * rattus norvegicus 64.2 39.55 4 PMID:4405600;PMID:7174633;PMID:7316984 -1.5.1.34 * thermus thermophilus 26.2 15.7 2 PMID:14702303 -1.5.1.36 * escherichia coli 25.1 12.709000000000001 2 PMID:12809507 -1.5.1.36 * lactobacillus johnsonii 0.2 0.2 1 PMID:24487531 -1.5.1.36 * mycolicibacterium goodii 617.0 18.65 6 * -1.5.1.38 * vibrio harveyi 88.4 51.0 3 PMID:1175652;PMID:8206832;PMID:880288 -1.5.1.39 * lacticaseibacillus rhamnosus 39.8 39.8 1 PMID:32044036 -1.5.1.40 * archaeoglobus fulgidus 660.0 660.0 1 * -1.5.1.40 * halobacterium salinarum 363.0 363.0 1 * -1.5.1.40 * methanobacterium palustre 0.3 0.3 1 PMID:9325428 -1.5.1.40 * methanococcus vannielii 1.79 1.79 1 PMID:7391030 -1.5.1.40 * methanoculleus thermophilus 0.04 0.04 1 PMID:9325428 -1.5.1.40 * methanofollis liminatans 0.06 0.06 1 PMID:9325428 -1.5.1.40 * methanogenium organophilum 998.0 506.55 2 PMID:9325428 -1.5.1.40 * streptomyces griseus 11.15 11.15 1 PMID:2492438 -1.5.1.41 * escherichia coli 0.36 0.36 1 PMID:3305505 -1.5.1.42 * vibrio harveyi 31.0 16.525 2 PMID:1175652;PMID:880288 -1.5.1.43 * vibrio alginolyticus 31.0 15.50835 2 PMID:1955861 -1.5.1.45 * geobacillus thermodenitrificans 58.2 56.835 2 PMID:19942660 -1.5.1.47 * hyphomicrobium nitrativorans 2.82 2.82 1 PMID:30364315 -1.5.1.47 * methylobacterium nodulans 0.63 0.63 1 PMID:30364315 -1.5.1.47 * methylorubrum extorquens 2.8 2.52 2 PMID:15028691;PMID:30364315 -1.5.1.48 * streptomyces sp. 10.2 5.10016 2 PMID:21897027 -1.5.1.49 * colwellia psychrerythraea 30.2 2.695 4 PMID:24649405 -1.5.1.5 * bos taurus 0.038 0.0245 2 PMID:4541693 -1.5.1.5 * elaphe quadrivirgata 0.092 0.0605 2 PMID:4541693 -1.5.1.5 * escherichia coli 31.2 31.2 1 PMID:350870 -1.5.1.5 * gallus gallus bankiva 0.164 0.096 2 PMID:4541693 -1.5.1.5 * homo sapiens 13.2 8.05 4 PMID:18767138;PMID:3074630 -1.5.1.5 * lathyrus oleraceus 32.5 32.5 1 PMID:8304211 -1.5.1.5 * leishmania major 22.0 22.0 2 PMID:19183277 -1.5.1.5 * mus musculus 12.7 6.53 3 PMID:2453205;PMID:3074630 -1.5.1.5 * neomoorella thermoacetica 720.0 362.0 3 PMID:4405422;PMID:6966369 -1.5.1.5 * ovis aries 0.05 0.029500000000000002 2 PMID:4541693 -1.5.1.5 * photobacterium phosphoreum 97.4 97.4 1 PMID:8765228 -1.5.1.5 * saccharomyces cerevisiae 259.0 259.0 1 PMID:14490085 -1.5.1.5 * salmonella enterica subsp. enterica serovar typhimurium 160.0 160.0 1 PMID:4382580 -1.5.1.5 * sus scrofa 61.0 61.0 1 PMID:6966370 -1.5.1.50 * pseudomonas aeruginosa 4.3 1.87 3 PMID:32482721 -1.5.1.53 * homo sapiens 0.367 0.367 1 PMID:2383427 -1.5.1.53 * sus scrofa 19.4 19.4 1 PMID:6975779 -1.5.1.54 * acetobacterium woodii 248.0 248.0 1 PMID:25733614 -1.5.1.54 * arabidopsis thaliana 6.9 6.9 1 PMID:10593891 -1.5.1.54 * blautia producta 380.0 380.0 1 PMID:2209595 -1.5.1.6 * danio rerio 1.04 1.04 1 PMID:20381623 -1.5.1.6 * mus musculus 0.00478 0.0037800000000000004 2 PMID:7972060 -1.5.1.6 * rattus norvegicus 0.7 0.26 5 PMID:3392008;PMID:36073;PMID:9765265 -1.5.1.6 * sus scrofa 0.98 0.575 4 PMID:3196754;PMID:3697368;PMID:4384443 -1.5.1.7 * meyerozyma guilliermondii 0.00018 0.00018 1 PMID:2515798 -1.5.1.7 * penicillium chrysogenum 0.402 0.3915 2 PMID:11717275 -1.5.1.7 * phycomyces blakesleeanus 0.09 0.09 1 PMID:418069 -1.5.1.7 * saccharomyces cerevisiae 106.0 12.350000000000001 4 PMID:418069;PMID:4318475 -1.5.1.8 * bos taurus 17.0 17.0 1 PMID:3110158;PMID:6434529 -1.5.1.8 * glycine max 3.261 3.261 1 PMID:10859195 -1.5.1.8 * hordeum vulgare 0.00039 0.00039 1 PMID:25559386 -1.5.1.8 * papio sp. 17.1 17.1 1 PMID:6434529 -1.5.1.8 * phaseolus vulgaris 4.98 4.98 1 PMID:12624751 -1.5.1.8 * rattus norvegicus 28.3 28.3 1 PMID:687635 -1.5.1.8 * sorghum bicolor 21.34 21.34 1 PMID:15740075 -1.5.1.8 * zea mays 1.273 1.273 1 PMID:9654071 -1.5.1.9 * bos taurus 0.0045 0.0045 1 PMID:4774398 -1.5.1.9 * canis lupus familiaris 0.0055 0.0055 1 PMID:4774398 -1.5.1.9 * felis catus 0.0069 0.0069 1 PMID:4774398 -1.5.1.9 * glycine max 2.608 1.30475 2 * -1.5.1.9 * homo sapiens 0.0047 0.0047 1 PMID:4774398 -1.5.1.9 * hordeum vulgare 0.00227 0.00227 1 PMID:25559386 -1.5.1.9 * oryza sativa 0.052 0.02685 2 PMID:9249048 -1.5.1.9 * ovis aries 0.0054 0.0054 1 PMID:4774398 -1.5.1.9 * papio hamadryas 17.2 8.615 2 PMID:6434529 -1.5.1.9 * phaseolus vulgaris 16.8 16.8 1 PMID:12624751 -1.5.1.9 * rattus norvegicus 0.005 0.005 1 PMID:4774398 -1.5.1.9 * sorghum bicolor 4.54 4.54 1 PMID:15740075 -1.5.1.9 * sus scrofa 0.0058 0.0058 1 PMID:4774398 -1.5.1.9 * zea mays 2.14 1.0712000000000002 2 PMID:12226216 -1.5.3.1 * arthrobacter sp. 2.38 2.02 3 * -1.5.3.1 * bacillus sp. (in: firmicutes) 44.8 27.0 5 PMID:15850379;PMID:16878980 -1.5.3.1 * corynebacterium sp. 8.93 8.93 1 PMID:7240129 -1.5.3.1 * cylindrocarpon didymum 27.6 27.6 1 * -1.5.3.1 * paenarthrobacter ureafaciens 7.3 7.3 1 * -1.5.3.1 * streptomyces sp. 25.0 25.0 1 PMID:3435943 -1.5.3.10 * cylindrocarpon didymum 12.3 12.3 1 * -1.5.3.15 * acanthamoeba culbertsoni 4.506 4.506 1 PMID:1565141 -1.5.3.16 * ascaris suum 2.3 2.3 1 PMID:1567380 -1.5.3.16 * mus musculus 5.0 5.0 1 PMID:15313165 -1.5.3.17 * ascaris suum 2.3 2.3 1 PMID:1567380 -1.5.3.18 * schizosaccharomyces pombe 6.72 6.72 1 PMID:16233628 -1.5.3.20 * cladosporium sp. 4.2 4.2 1 PMID:9989229 -1.5.3.22 * methanobrevibacter arboriphilus 55.0 27.7 2 PMID:15340796 -1.5.3.23 * brucella anthropi 0.034 0.0335 2 PMID:21639854 -1.5.3.24 * corynebacterium sp. p-1 12.2 8.6 3 PMID:3790506;PMID:9485355 -1.5.3.24 * corynebacterium sp. u-96 8.93 4.655 2 PMID:7240129 -1.5.3.25 * pichia sp. n1-1 0.52 0.52 1 PMID:20383736 -1.5.3.26 * pseudomonas sp. 15.38 15.38 1 PMID:8955117 -1.5.3.4 * rattus norvegicus 0.0433 0.0283 5 PMID:14257609;PMID:4441079;PMID:6238220 -1.5.3.5 * agrobacterium tumefaciens 0.462 0.462 1 PMID:22466953 -1.5.3.5 * paenarthrobacter nicotinovorans 4.73 4.73 1 PMID:5646150 -1.5.3.6 * paenarthrobacter nicotinovorans 32.0 22.5 5 PMID:3905431;PMID:4628374;PMID:6618442;PMID:9878353 -1.5.3.7 * penicillium chrysogenum 0.002 0.002 1 PMID:11717275 -1.5.4.1 * drosophila melanogaster 124.0 62.4 2 PMID:16712527;PMID:6438092 -1.5.5.1 * homo sapiens 17.6 0.99 4 PMID:12049629;PMID:7757062;PMID:8306995 -1.5.5.1 * sus scrofa 28.6 14.3465 2 PMID:1991113;PMID:4052375 -1.5.5.2 * escherichia coli 7.3 4.27 2 PMID:1618807;PMID:355248 -1.5.5.2 * pyrococcus horikoshii 0.014 0.014 1 PMID:22089387 -1.5.5.2 * thermococcus profundus 0.68 0.68 1 PMID:15064976 -1.5.5.2 * thermus thermophilus 4.95 4.74 5 PMID:25545499;PMID:28256579 -1.5.7.1 * clostridium formicaceticum 139.0 139.0 1 PMID:6381490 -1.5.7.1 * clostridium ljungdahlii 156.1 156.1 1 PMID:34255221 -1.5.7.1 * neomoorella thermoacetica 16.0 16.0 1 PMID:25002540 -1.5.8.1 * hyphomicrobium sp. 0.3638 0.3638 1 * -1.5.8.1 * paracoccus sp. (in: a-proteobacteria) 95.0 50.65 2 PMID:11685371 -1.5.8.2 * hyphomicrobium sp. 0.6 0.6 1 PMID:454446 -1.5.8.2 * methylophilus methylotrophus 1.1 0.5980000000000001 4 PMID:1200991;PMID:3223938 -1.5.8.2 * methylotrophic bacterium 2.0 2.0 1 PMID:4462741 -1.5.8.2 * paracoccus sp. (in: a-proteobacteria) 23.0 0.107 9 PMID:11685371;PMID:12951251 -1.5.8.2 * pseudomonas putida 3.1e-05 3.1e-05 1 PMID:20437165 -1.5.8.3 * rattus norvegicus 0.279 0.279 1 PMID:3702694 -1.5.8.3 * sinorhizobium meliloti 0.0057 0.0057 1 PMID:3290197 -1.5.8.3 * sus scrofa 0.263 0.263 1 PMID:6180732 -1.5.8.4 * homo sapiens 0.165 0.165 1 PMID:18937046 -1.5.8.4 * rattus norvegicus 129.0 41.284 4 PMID:13895406;PMID:15358367;PMID:2417560;PMID:6159630 -1.5.8.4 * sus scrofa 0.157 0.157 1 PMID:6180732 -1.5.98.1 * archaeoglobus fulgidus 1560.0 788.35 2 PMID:8481089 -1.5.98.1 * archaeoglobus lithotrophicus 0.24 0.24 1 * -1.5.98.1 * archaeoglobus profundus 0.01 0.01 1 * -1.5.98.1 * ferroglobus placidus 1.5 1.5 1 PMID:9000337 -1.5.98.1 * methanopyrus kandleri 3700.0 2510.0 2 PMID:19761261;PMID:8215796 -1.5.98.1 * methanosarcina barkeri 670.0 670.0 1 PMID:1911853 -1.5.98.1 * methanothermobacter thermautotrophicus 736.0 197.0 3 PMID:1991149;PMID:2743220;PMID:4084309 -1.5.98.1 * uncultured archaeon 1100.0 1100.0 1 PMID:24707918 -1.5.98.2 * archaeoglobus fulgidus 1.0 1.0 1 * -1.5.98.2 * archaeoglobus lithotrophicus 0.06 0.06 1 * -1.5.98.2 * archaeoglobus profundus 0.01 0.01 1 * -1.5.98.2 * ferroglobus placidus 0.4 0.4 1 PMID:9000337 -1.5.98.2 * methanopyrus kandleri 290.0 290.0 2 PMID:1953299 -1.5.98.2 * methanosarcina barkeri 31.5 31.5 1 PMID:1911853 -1.5.98.2 * methanothermobacter thermautotrophicus 290.0 226.5 2 PMID:2379499 -1.5.98.3 * methanosarcina mazei 10.4 1.8 11 PMID:9555882 -1.5.99.12 * arabidopsis thaliana 0.0052 0.0052 1 * -1.5.99.12 * nicotiana tabacum 0.0065 0.002 7 * -1.5.99.12 * zea mays 62.4 46.5 2 PMID:15272190;PMID:15927342 -1.5.99.13 * pyrobaculum islandicum 13.2 9.25 2 PMID:11823469 -1.5.99.14 * pseudarthrobacter oxydans 28.3 28.3 1 * -1.5.99.4 * agrobacterium tumefaciens 110.0 66.0 2 PMID:28625985 -1.5.99.4 * oryctolagus cuniculus 0.0222 0.01435 2 PMID:2302249 -1.5.99.4 * pseudarthrobacter oxydans 29.2 28.75 2 PMID:4962139 -1.5.99.4 * pseudomonas putida 1096.0 1096.0 1 PMID:4354821 -1.5.99.4 * rattus norvegicus 0.000514 0.000514 1 PMID:7074142 -1.5.99.5 * aminobacter aminovorans 0.29 0.00307 8 PMID:15545;PMID:597255 -1.5.99.5 * bacterium at2 0.113 0.03535 4 * -1.5.99.5 * hyphomicrobium vulgare 0.0161 0.0161 1 * -1.5.99.5 * pseudomonas sp. 2.6 1.45 2 PMID:4399353 -1.5.99.6 * citrobacter freundii 130.7 97.5 3 PMID:1369091 -1.5.99.6 * glycine max 800.0 800.0 1 * -1.5.99.6 * pseudomonas aeruginosa 7.52 7.52 1 * -1.5.99.6 * serratia marcescens 440.0 436.0 3 PMID:376502;PMID:376503;PMID:4918845;PMID:6353158 -1.6.1.1 * azotobacter vinelandii 575.0 260.5 6 PMID:4392895;PMID:4400341;PMID:4400342;PMID:4404238;PMID:7460901 -1.6.1.1 * chromatium sp. 24.0 24.0 1 * -1.6.1.1 * lathyrus oleraceus 0.0094 0.0094 1 PMID:10548498 -1.6.1.1 * pseudomonas aeruginosa 220.0 218.5 2 PMID:823872 -1.6.1.1 * pseudomonas fluorescens 11.5 11.5 1 * -1.6.1.1 * solanum tuberosum 0.0131 0.0131 1 PMID:10548498 -1.6.1.3 * azotobacter vinelandii 575.0 287.78 2 PMID:7460901 -1.6.2.2 * badhamia polycephala 48.4 48.4 1 PMID:17341833 -1.6.2.2 * bos taurus 137.0 137.0 1 PMID:6654871 -1.6.2.2 * canis lupus familiaris 14.9 14.9 1 PMID:16814740 -1.6.2.2 * homo sapiens 1510.0 785.0 5 PMID:2498303;PMID:2500149;PMID:2992639;PMID:7294831;PMID:8883403 -1.6.2.2 * lathyrus oleraceus 0.18 0.18 1 PMID:16665720 -1.6.2.2 * mucor racemosus 300.0 300.0 1 PMID:19746258 -1.6.2.2 * mus musculus 0.00072 0.00072 1 PMID:8602879 -1.6.2.2 * musca domestica 1007.0 504.521 2 PMID:8936052 -1.6.2.2 * oryctolagus cuniculus 1575.0 622.5 5 PMID:175049;PMID:28780;PMID:672620;PMID:7096301;PMID:7986089 -1.6.2.2 * ovis aries 670.0 670.0 1 PMID:10216966 -1.6.2.2 * phascolopsis gouldii 611.1 138.0 5 PMID:2597703 -1.6.2.2 * rattus norvegicus 2480.0 1470.0 5 PMID:4315302;PMID:7986089;PMID:8027853;PMID:8812833 -1.6.2.2 * saccharomyces cerevisiae 69.8 69.8 1 PMID:14930 -1.6.2.2 * solanum tuberosum 628.0 628.0 1 * -1.6.2.2 * sus scrofa 0.372 0.07680000000000001 4 PMID:2369123 -1.6.2.2 * zea mays 628.0 628.0 1 * -1.6.2.4 * andrographis paniculata 8.83 5.83 2 PMID:28410952 -1.6.2.4 * aspergillus ochraceus 0.119 0.119 1 PMID:6810893 -1.6.2.4 * bos taurus 14.5 14.5 1 PMID:12481304 -1.6.2.4 * botryococcus braunii 80.3 80.3 1 PMID:28818427 -1.6.2.4 * brassica rapa 0.02 0.011 2 PMID:53032 -1.6.2.4 * candida tropicalis 70.0 27.0 12 PMID:107026;PMID:6772182 -1.6.2.4 * catharanthus roseus 22.0 1.429 5 PMID:107158 -1.6.2.4 * cavia porcellus 34.2 17.44 2 PMID:6094521;PMID:7396894 -1.6.2.4 * centaurium erythraea 4.0 4.0 1 PMID:19470102 -1.6.2.4 * coleus scutellarioides 0.52 0.52 1 PMID:18982412 -1.6.2.4 * cutaneotrichosporon cutaneum 1.0 0.85 2 PMID:6397156 -1.6.2.4 * delphinapterus leucas 0.079 0.0775 2 PMID:8184432 -1.6.2.4 * dictyostelium discoideum 0.0438 0.0345 4 PMID:202379;PMID:401646 -1.6.2.4 * equus caballus 40.0 40.0 1 PMID:2106448 -1.6.2.4 * fusarium oxysporum 10.5 4.15 4 * -1.6.2.4 * gallus gallus 0.788 0.788 1 PMID:219782 -1.6.2.4 * gossypium hirsutum 9.84 4.08 8 PMID:19883924 -1.6.2.4 * helianthus tuberosus 33.0 33.0 1 PMID:3091006 -1.6.2.4 * homo sapiens 36.0 0.517 9 PMID:7771780;PMID:9468503;PMID:9511179 -1.6.2.4 * locusta migratoria migratorioides 0.051 0.029 3 PMID:27363 -1.6.2.4 * lodderomyces elongisporus 98.3 68.9 3 PMID:6810895 -1.6.2.4 * mesocricetus auratus 26.0 26.0 1 PMID:3111296 -1.6.2.4 * mus musculus 0.258 0.105 7 PMID:202308;PMID:807209 -1.6.2.4 * nitrobacter winogradskyi 8.64 8.64 1 * -1.6.2.4 * oryctolagus cuniculus 38.0 21.0 2 PMID:2109611;PMID:4145653 -1.6.2.4 * petunia x hybrida 60.0 30.01 2 PMID:7991686 -1.6.2.4 * phanerodontia chrysosporium 14.76 9.015 2 PMID:12437968 -1.6.2.4 * picrorhiza kurrooa 5.8 5.8 1 PMID:24522789 -1.6.2.4 * rattus norvegicus 102.0 0.698 42 PMID:102260;PMID:11022049;PMID:117798;PMID:2106448;PMID:240313;PMID:2708380;PMID:3084464;PMID:3111296;PMID:3120697;PMID:3924902;PMID:3925992;PMID:3947076;PMID:4152897;PMID:4153077;PMID:4154900;PMID:4392647;PMID:6405660;PMID:8281920;PMID:9774150 -1.6.2.4 * saccharomyces cerevisiae 150.0 12.1905 6 PMID:120699;PMID:14931;PMID:4154327;PMID:9468503 -1.6.2.4 * sparus aurata 0.0233 0.0233 1 * -1.6.2.4 * spodoptera eridania 40.5 40.5 1 PMID:117798 -1.6.2.4 * spodoptera frugiperda 0.0128 0.0128 1 PMID:7771780 -1.6.2.4 * sus scrofa 26.1 0.087 9 PMID:3125159;PMID:3926000;PMID:4149281;PMID:4371831 -1.6.2.4 * tetrahymena pyriformis 0.0144 0.01065 6 PMID:4332792 -1.6.2.4 * trichoplusia ni 0.0173 0.0173 1 PMID:7771780 -1.6.2.4 * trypanosoma cruzi 0.059 0.0545 2 PMID:3923933 -1.6.2.4 * tulipa fosteriana 0.0775 0.040105 2 PMID:10897475 -1.6.2.4 * vigna radiata var. radiata 41.1 29.400000000000002 4 PMID:183822 -1.6.2.4 * withania somnifera 7.56 7.195 2 PMID:23437311 -1.6.2.4 * xenopus laevis 23.4 23.4 1 PMID:16483612 -1.6.2.5 * cereibacter sphaeroides 164.0 164.0 1 PMID:4385431 -1.6.2.6 * glycine max 4.89 1.175 10 PMID:11607104;PMID:12232320;PMID:16652965;PMID:16668174;PMID:6539095 -1.6.2.6 * vigna unguiculata 2.565 1.3905 2 PMID:10729615 -1.6.3.1 * bos taurus 0.033 0.024 2 PMID:8382922 -1.6.3.1 * saccharolobus solfataricus 2.8 2.8 1 PMID:10625624 -1.6.3.1 * sus scrofa 0.002 0.00135 2 PMID:10401672;PMID:3125160 -1.6.3.1 * thermococcus kodakarensis 0.38 0.27 2 PMID:21830202 -1.6.3.3 * archaeoglobus fulgidus 5.81 4.05 3 PMID:11717257;PMID:12823559 -1.6.3.3 * brevibacterium sp. 5.2 5.2 1 PMID:18521590 -1.6.3.3 * pseudothermotoga hypogea 30.0 30.0 1 PMID:15912375 -1.6.3.3 * pyrococcus horikoshii 84.0 84.0 1 * -1.6.3.3 * streptococcus mutans 37.0 37.0 1 PMID:8254304 -1.6.3.3 * thermotoga maritima 144.0 144.0 1 PMID:17293421 -1.6.3.4 * anaerocolumna aminovalerica 130.0 130.0 1 PMID:15014929 -1.6.3.4 * streptococcus mutans 281.2 190.75 2 PMID:29514042;PMID:8254304 -1.6.3.5 * homo sapiens 87.6 63.0 3 PMID:33180865 -1.6.5.10 * escherichia coli 1067.0 1067.0 1 PMID:8611590 -1.6.5.10 * homo sapiens 1.258 1.1775 2 PMID:8529642 -1.6.5.10 * mus musculus 0.0012 0.0007 3 PMID:17588258 -1.6.5.10 * rattus norvegicus 0.0044 0.0038 3 PMID:9692994 -1.6.5.10 * spinacia oleracea 28.1 28.1 1 * -1.6.5.2 * archaeoglobus fulgidus 25000.0 4050.0 6 PMID:16672604 -1.6.5.2 * canis lupus familiaris 2.9 2.9 1 PMID:13846011 -1.6.5.2 * clostridium tyrobutyricum 46.2 46.2 1 PMID:7407710 -1.6.5.2 * cupriavidus pinatubonensis jmp134 911.4 35.3 5 PMID:18165297 -1.6.5.2 * escherichia coli 990.0 495.0 6 PMID:16672604 -1.6.5.2 * glycine max 2469.0 2469.0 1 PMID:7603972 -1.6.5.2 * helicobacter hepaticus 4.0 4.0 1 PMID:17923370 -1.6.5.2 * hevea brasiliensis 1.23 1.23 1 PMID:12169304 -1.6.5.2 * homo sapiens 800.0 0.011 35 PMID:10423172;PMID:17455910;PMID:18444152;PMID:22074961;PMID:23635904;PMID:28478157 -1.6.5.2 * mus musculus 1770.0 1745.0 2 PMID:2418014 -1.6.5.2 * octopus vulgaris 2.8 2.8 1 PMID:4171422 -1.6.5.2 * phanerodontia chrysosporium 217.0 217.0 1 PMID:16535104 -1.6.5.2 * rattus norvegicus 5860.0 0.255 36 PMID:10683249;PMID:1372830;PMID:17573173;PMID:18329153;PMID:2233301;PMID:2500115;PMID:3214167;PMID:56919 -1.6.5.4 * cucumis sativus 256.0 256.0 1 PMID:4055727 -1.6.5.4 * hordeum vulgare 185.0 185.0 1 PMID:16341544 -1.6.5.4 * ipomoea batatas 0.00552 0.004484999999999999 2 PMID:28510854 -1.6.5.4 * oryza sativa japonica group 380.0 380.0 1 * -1.6.5.4 * physcomitrium patens 164.0 158.0 2 PMID:16983536 -1.6.5.4 * pleurotus ostreatus 11.09 11.09 1 * -1.6.5.4 * solanum tuberosum 61.0 61.0 1 PMID:24240368 -1.6.5.4 * spinacia oleracea 100.0 18.55 4 PMID:15849415 -1.6.5.5 * camelus dromedarius 25.1 25.1 1 PMID:7488002 -1.6.5.5 * cavia porcellus 6.0 6.0 1 PMID:1420281 -1.6.5.5 * homo sapiens 0.64 0.64 1 PMID:33483563 -1.6.5.5 * staphylococcus aureus 311.0 162.9 2 PMID:12624201 -1.6.5.7 * burkholderia cepacia 68.0 35.5 2 PMID:9721310 -1.6.5.9 * arum maculatum 3372.0 69.2 3 PMID:6745260 -1.6.5.9 * saccharomyces cerevisiae 1671.0 61.9 3 PMID:3138118 -1.7.1.1 * arabidopsis thaliana 32.0 32.0 1 PMID:9390442 -1.7.1.1 * auxenochlorella pyrenoidosa 1.747 1.747 1 PMID:16658375 -1.7.1.1 * chlorella vulgaris 92.68 92.68 1 PMID:500668 -1.7.1.1 * cucurbita maxima 100.0 97.5 2 PMID:4038708;PMID:6684426 -1.7.1.1 * cucurbita pepo 2.0 1.95 2 PMID:16660347 -1.7.1.1 * emiliania huxleyi 52.33 52.33 1 PMID:12925915 -1.7.1.1 * fusarium oxysporum 10.5 10.5 2 PMID:18256499 -1.7.1.1 * glycine max 23.5 16.505 2 PMID:16664214 -1.7.1.1 * gracilaria tenuistipitata 3.37 3.37 1 PMID:12083765 -1.7.1.1 * hordeum vulgare 37.0 8.0 3 * -1.7.1.1 * nicotiana plumbaginifolia 82.0 82.0 1 PMID:2920729 -1.7.1.1 * pyropia yezoensis 12.5 12.5 1 * -1.7.1.1 * skeletonema costatum 3.0 3.0 1 PMID:12232038 -1.7.1.1 * spinacia oleracea 103.0 13.65 6 PMID:12139973;PMID:16663994 -1.7.1.1 * thalassiosira pseudonana 4.0 4.0 1 * -1.7.1.1 * triticum aestivum 23.1 22.450000000000003 2 PMID:16660726 -1.7.1.1 * triticum turgidum subsp. durum 0.045 0.0295 4 * -1.7.1.1 * zea mays 60.0 30.445 2 PMID:16660347;PMID:16663612 -1.7.1.10 * derxia gummosa 0.68 0.551 2 * -1.7.1.10 * escherichia coli 458.0 458.0 1 PMID:12374823 -1.7.1.11 * rattus norvegicus 0.27 0.27 1 PMID:3152268 -1.7.1.12 * oryctolagus cuniculus 910.0 910.0 1 PMID:4074379 -1.7.1.13 * escherichia coli 117.0 103.5 2 PMID:23595998 -1.7.1.15 * escherichia coli 62.4 31.226 2 PMID:7030314 -1.7.1.15 * rhodobacter capsulatus 2.0 2.0 1 PMID:16897035 -1.7.1.16 * ectopseudomonas oleovorans 245.0 245.0 1 PMID:7601851 -1.7.1.16 * gluconobacter oxydans 11000.0 11000.0 1 PMID:27138989 -1.7.1.16 * phanerodontia chrysosporium 3600.0 2750.0 2 PMID:7999039 -1.7.1.16 * pseudomonas sp. hk-6 5.01 5.01 1 * -1.7.1.16 * psychrobacter sp. ant206 51.59 51.59 1 PMID:31615682 -1.7.1.16 * salmonella enterica subsp. enterica serovar typhimurium 13.6 10.85 2 PMID:20449486 -1.7.1.17 * bacillus sp. b29 26.6 17.75 4 PMID:17546472 -1.7.1.17 * enterococcus faecalis 181.0 139.0 5 PMID:15003265;PMID:18791262 -1.7.1.17 * escherichia coli 441.0 188.6 5 * -1.7.1.17 * geobacillus stearothermophilus 25.8 25.8 1 PMID:19997911 -1.7.1.17 * lysinibacillus sphaericus 74.0 25.5 6 PMID:24068503 -1.7.1.17 * rhodococcus opacus 141.25 141.25 1 * -1.7.1.2 * [candida] nitratophila 217.4 217.4 1 * -1.7.1.2 * chlorella variegata 0.766 0.742 2 PMID:24408685 -1.7.1.2 * chlorolobion braunii 72.0 66.625 2 PMID:7200426 -1.7.1.2 * rhodotorula glutinis 148.2 74.75 2 PMID:16097946;PMID:18182 -1.7.1.2 * triticale sp. 0.455 0.000117 5 * -1.7.1.3 * aspergillus nidulans 16.0 0.019 11 PMID:15118339;PMID:4153024;PMID:4396143;PMID:4611763;PMID:7042701 -1.7.1.3 * bradyrhizobium sp. 0.37 0.2 4 PMID:14553930 -1.7.1.3 * fusarium oxysporum 177.1 177.1 1 PMID:24610039 -1.7.1.3 * neurospora crassa 8.55 4.32 3 PMID:23539622;PMID:4275465 -1.7.1.3 * tilia platyphyllos 0.003 0.0022 2 PMID:12898221 -1.7.1.4 * bacillus subtilis 33.4 24.0 2 PMID:9765565 -1.7.1.4 * bradyrhizobium sp. 0.18 0.115 4 PMID:14553930 -1.7.1.4 * cyberlindnera jadinii 60000.0 17300.0 5 PMID:9547218 -1.7.1.4 * derxia gummosa 0.868 0.645 2 * -1.7.1.4 * escherichia coli 16.7 8.44 2 PMID:14463130;PMID:217342 -1.7.1.4 * neurospora crassa 26.9 0.625 4 PMID:14426899;PMID:150863;PMID:4154942 -1.7.1.4 * rhizobium etli 0.000508 0.00026425 2 PMID:15667294 -1.7.1.4 * staphylococcus carnosus 0.504 0.2145 4 PMID:8606176 -1.7.1.6 * bacillus amyloliquefaciens 0.48 0.48 1 PMID:18034237 -1.7.1.6 * bacillus cereus 0.566 0.566 1 * -1.7.1.6 * bacillus sp. (in: firmicutes) 26.9 13.55 4 PMID:11134015 -1.7.1.6 * bacillus sp. b29 38.6 38.400000000000006 2 PMID:19420689 -1.7.1.6 * brevibacillus laterosporus 505.0 255.4 2 PMID:17601730 -1.7.1.6 * brevundimonas subvibrioides 69570.0 69570.0 1 * -1.7.1.6 * canis lupus familiaris 0.045 0.045 1 PMID:5380703 -1.7.1.6 * cavia porcellus 0.087 0.087 1 PMID:5380703 -1.7.1.6 * cereibacter sphaeroides 78.9 10.55 6 PMID:15212802 -1.7.1.6 * ectopseudomonas oleovorans 26.0 26.0 1 PMID:23768111 -1.7.1.6 * enterococcus faecalis 63.9 0.224 5 PMID:15003265;PMID:18791262 -1.7.1.6 * enterococcus faecium 5095.0 21.95 20 PMID:19741272 -1.7.1.6 * escherichia coli 0.32 0.151 8 PMID:8112774 -1.7.1.6 * gallus gallus 0.053 0.053 1 PMID:5380703 -1.7.1.6 * geobacillus stearothermophilus 25.8 13.0 2 PMID:19997911 -1.7.1.6 * microtus pennsylvanicus 0.06 0.06 1 PMID:5380703 -1.7.1.6 * pigmentiphaga kullae 10.1 2.9 3 PMID:12719939;PMID:20233432 -1.7.1.6 * pseudomonas sp. 17830.0 2868.0 3 PMID:6742955;PMID:7160382 -1.7.1.6 * pseudomonas sp. b1 19.8 19.8 1 * -1.7.1.6 * rattus norvegicus 57.0 0.0095 14 PMID:108265;PMID:5380703;PMID:744412;PMID:91608;PMID:923973;PMID:9475082 -1.7.1.6 * shewanella oneidensis 184.6 158.36 4 PMID:23089953 -1.7.1.6 * shewanella sp. ifn4 139.63 71.59 2 * -1.7.1.6 * shewanella xiamenensis 97153.0 5152.0 3 * -1.7.1.6 * staphylococcus aureus 0.14 0.07750000000000001 2 PMID:15870453 -1.7.1.6 * xenophilus azovorans 10.8 10.8 1 PMID:12147495 -1.7.1.7 * artemia salina 0.564 0.32099999999999995 2 PMID:4151342;PMID:990256 -1.7.1.7 * bacillus subtilis 0.0051 0.0051 1 PMID:6408059 -1.7.1.7 * escherichia coli 0.8 0.73 2 PMID:21298178;PMID:3005121 -1.7.1.7 * homo sapiens 0.35 0.17759999999999998 2 PMID:218932;PMID:4149840 -1.7.1.7 * mycoplasma mycoides 0.003 0.003 1 PMID:207675 -1.7.1.7 * trypanosoma brucei brucei 43.8 30.6 3 PMID:26731263 -1.7.1.9 * canis lupus familiaris 0.3 0.3 1 PMID:98382 -1.7.1.9 * cavia porcellus 0.4 0.4 1 * -1.7.1.9 * cricetinae 0.18 0.18 1 * -1.7.1.9 * felis catus 0.12 0.12 1 * -1.7.1.9 * oryctolagus cuniculus 0.07 0.07 1 * -1.7.1.9 * rattus norvegicus 0.5 0.15 7 PMID:2117996 -1.7.2.1 * achromobacter xylosoxidans 240.0 167.7 7 PMID:10197991;PMID:11139389;PMID:12082116;PMID:19053252 -1.7.2.1 * alcaligenes faecalis 417.0 417.0 1 PMID:12538888 -1.7.2.1 * alcaligenes sp. 117.0 23.049999999999997 4 PMID:4086480;PMID:6501252 -1.7.2.1 * cereibacter sphaeroides 80.0 60.0 2 * -1.7.2.1 * cupriavidus necator 2.58 2.58 1 PMID:8048839 -1.7.2.1 * fusarium oxysporum 303.0 303.0 1 PMID:19270125 -1.7.2.1 * haloarcula marismortui 960.0 960.0 1 PMID:11418554 -1.7.2.1 * hydrogenobacter thermophilus 0.202 0.202 1 PMID:16781467 -1.7.2.1 * paracoccus denitrificans 1.27 1.27 1 PMID:4309366 -1.7.2.1 * paramagnetospirillum magnetotacticum 3.32 3.32 1 PMID:7588814 -1.7.2.1 * pseudomonas chlororaphis 130.0 65.165 2 PMID:15182351 -1.7.2.1 * pseudomonas nautica 617 0.048 0.048 1 PMID:16887530 -1.7.2.1 * thiobacillus denitrificans 2.1 2.1 1 PMID:8639023 -1.7.2.2 * aliivibrio fischeri 682.0 682.0 1 PMID:2833168 -1.7.2.2 * caminibacter mediatlanticus 158.0 1.0 3 PMID:28388834 -1.7.2.2 * campylobacter curvus 68.0 27.0 3 PMID:28388834 -1.7.2.2 * campylobacter fetus subsp. fetus 181.0 149.0 3 PMID:28388834 -1.7.2.2 * desulfovibrio desulfuricans 345.0 345.0 1 PMID:2833168 -1.7.2.2 * escherichia coli 25.0 25.0 1 PMID:18245085 -1.7.2.2 * escherichia coli k-12 2930.0 2690.0 5 PMID:3002798 -1.7.2.2 * lacticaseibacillus casei 1851.0 1851.0 1 * -1.7.2.2 * nautilia profundicola 29.0 1.2 3 PMID:28388834 -1.7.2.2 * nitratidesulfovibrio vulgaris str. hildenborough 685.0 685.0 1 PMID:11004582 -1.7.2.2 * sulfurospirillum deleyianum 1050.0 1010.0 2 PMID:7999130 -1.7.2.2 * thioalkalivibrio nitratireducens 4080.0 2115.0 2 PMID:16500161;PMID:18298372 -1.7.2.2 * wolinella succinogenes 850.0 810.0 3 PMID:2833168;PMID:7999130 -1.7.2.3 * alteromonas sp. 0.56 0.25 5 * -1.7.2.3 * erythrobacter sp. 320.0 70.0 3 PMID:3170512 -1.7.2.3 * escherichia coli 1720.0 38.5 12 PMID:10216869;PMID:3282544;PMID:3528139;PMID:8022286;PMID:8639717;PMID:9632735 -1.7.2.3 * rhodobacter capsulatus 30.0 30.0 1 PMID:9165084 -1.7.2.3 * rhodospirillum rubrum 10.2 5.165 2 * -1.7.2.3 * roseobacter denitrificans 49.5 49.5 1 PMID:1337081 -1.7.2.3 * salmonella enterica subsp. enterica serovar typhimurium 9.92 4.215 4 PMID:6309742 -1.7.2.3 * shewanella sp. 211.5 211.5 1 * -1.7.2.4 * achromobacter cycloclastes 145.6 92.85 4 PMID:15012115;PMID:16904686;PMID:17257001;PMID:17681606 -1.7.2.4 * achromobacter xylosoxidans 6.0 6.0 1 PMID:10092849 -1.7.2.4 * cereibacter sphaeroides 78.0 50.4 3 PMID:10220576;PMID:9644245 -1.7.2.4 * hyphomicrobium denitrificans 45.0 37.0 2 PMID:14769874 -1.7.2.4 * marinobacter nauticus 92.4 39.0 6 PMID:10747777;PMID:22451106 -1.7.2.4 * paracoccus denitrificans 122.0 30.0 3 PMID:16087179;PMID:3032972 -1.7.2.4 * paracoccus pantotrophus 8.8 3.3 9 PMID:11041839;PMID:12049645;PMID:8383047 -1.7.2.4 * pseudomonas aeruginosa 27.0 27.0 1 PMID:1899237 -1.7.2.4 * stutzerimonas stutzeri 453.0 229.25 2 PMID:11041839;PMID:21938458 -1.7.2.4 * thiobacillus denitrificans 0.05 0.05 1 PMID:8639023 -1.7.2.4 * wolinella succinogenes 160.0 160.0 1 PMID:2536696 -1.7.2.5 * achromobacter cycloclastes 0.0028 0.0028 1 PMID:3028488 -1.7.2.5 * aspergillus oryzae 75.0 75.0 1 PMID:15502348 -1.7.2.5 * cupriavidus necator 2.79 1.155 6 PMID:10571051 -1.7.2.5 * cutaneotrichosporon cutaneum 295.0 270.0 2 PMID:11389721 -1.7.2.5 * halomonas halodenitrificans 22.2 22.2 1 PMID:9374857 -1.7.2.5 * paracoccus denitrificans 25.8 10.5 6 PMID:1645715;PMID:2167070;PMID:2920732;PMID:3028488;PMID:9030265 -1.7.2.5 * pseudomonas aeruginosa 0.004 0.004 1 PMID:3028488 -1.7.2.5 * roseobacter denitrificans 7.3 7.3 1 PMID:12038974 -1.7.2.5 * stutzerimonas stutzeri 60.0 11.8 3 PMID:2542222;PMID:3028488;PMID:8020468 -1.7.2.5 * synechocystis sp. 0.101 0.101 1 PMID:11823206 -1.7.2.6 * alcaligenes faecalis 0.09204 0.001836 6 PMID:31420725 -1.7.2.6 * bacillus sp. k5 0.022 0.014 7 PMID:29236024 -1.7.2.6 * caminibacter mediatlanticus 158.0 79.5 2 PMID:28388834 -1.7.2.6 * campylobacter curvus 68.0 47.5 2 PMID:28388834 -1.7.2.6 * campylobacter fetus 181.0 165.0 2 PMID:28388834 -1.7.2.6 * nautilia profundicola 29.0 15.1 2 PMID:28388834 -1.7.2.6 * nitrosomonas communis 25.6 25.6 1 PMID:16233712 -1.7.2.6 * nitrosomonas europaea 28.0 4.77 4 PMID:16233712;PMID:5758552;PMID:698180 -1.7.2.6 * nitrosomonas sp. k1 11.63 11.63 1 PMID:16233712 -1.7.2.7 * candidatus jettenia caeni 0.33 0.33 1 PMID:25367004 -1.7.2.8 * candidatus jettenia caeni 9.6 9.6 3 PMID:17172456;PMID:18397776 -1.7.2.8 * candidatus kuenenia stuttgartensis 8.4 4.4750000000000005 2 PMID:27317665 -1.7.2.8 * candidatus maribeggiatoa 0.46 0.46 1 PMID:23220958 -1.7.3.1 * fusarium oxysporum 10.6 10.6 1 PMID:11867731 -1.7.3.3 * [candida] sp. 12.2 12.2 1 PMID:8203871 -1.7.3.3 * aspergillus flavus 27.0 23.6 4 PMID:16545578 -1.7.3.3 * bacillus cereus 87.0 47.35 2 * -1.7.3.3 * bacillus sp. (in: firmicutes) 5.29 5.29 1 PMID:12182822 -1.7.3.3 * bacillus subtilis 39.0 28.5 2 PMID:20168977 -1.7.3.3 * canis lupus familiaris 4.22 4.22 1 PMID:22481018 -1.7.3.3 * cyberlindnera jadinii 38.4 10.48 5 PMID:18596202;PMID:21573940 -1.7.3.3 * enterobacter cloacae 6.6 6.6 1 * -1.7.3.3 * glycine max 6.85 5.225 2 PMID:6685457;PMID:9125493 -1.7.3.3 * kluyveromyces marxianus 50.54 27.95 2 PMID:30221113 -1.7.3.3 * latimeria menadoensis 10.45 10.45 1 PMID:30871218 -1.7.3.3 * metabacillus fastidiosus 9.0 7.9 2 PMID:27614625;PMID:34014494 -1.7.3.3 * microbacterium sp. 5.32 5.32 1 * -1.7.3.3 * ogataea angusta 2.67 1.3685 2 PMID:21612631 -1.7.3.3 * phaseolus vulgaris 1790.0 13.3 5 PMID:9414545 -1.7.3.3 * pseudomonas aeruginosa 15.0 15.0 1 PMID:25588559 -1.7.3.3 * puccinia recondita 8.4 8.4 1 PMID:11910495 -1.7.3.3 * rattus norvegicus 15.3 9.35 3 PMID:5362920;PMID:639984 -1.7.3.3 * streptomyces cyanogenus 12.3 12.3 1 PMID:7287651 -1.7.3.3 * uromyces phaseoli 3.11 3.11 1 * -1.7.3.3 * uromyces viciae-fabae 2.04 2.04 1 * -1.7.3.3 * vigna unguiculata 5.6 5.6 1 PMID:7248313 -1.7.3.5 * penicillium atrovenetum 274.0 217.0 2 PMID:3667582 -1.7.3.6 * pseudomonas sp. 3.6 3.6 1 PMID:9082922 -1.7.5.1 * pseudomonas chlororaphis 2.6 2.6 1 PMID:15804488 -1.7.5.2 * pyrobaculum aerophilum 3.28 3.28 1 PMID:12799376 -1.7.5.2 * schinkia azotoformans 40.7 20.685000000000002 2 PMID:11327887 -1.7.7.1 * chlamydomonas reinhardtii 89.0 89.0 1 * -1.7.7.1 * chlorolobion braunii 214.4 214.4 1 * -1.7.7.1 * cucurbita pepo 85.0 85.0 1 * -1.7.7.1 * cyberlindnera jadinii 16.06 16.06 1 PMID:8694757 -1.7.7.1 * haloferax mediterranei 15.8 15.8 1 PMID:11267765 -1.7.7.1 * leptolyngbya laminosa 625.0 625.0 1 PMID:2119228 -1.7.7.1 * limnospira platensis 194.0 194.0 1 * -1.7.7.1 * oryza sativa 181.0 90.505 2 * -1.7.7.1 * scenedesmus fuscus 51.7 51.7 1 PMID:5068817 -1.7.7.1 * spinacia oleracea 301.4 127.5 12 PMID:5954064;PMID:7487061;PMID:838704;PMID:914814 -1.7.7.1 * vigna angularis 53.4 53.4 1 * -1.7.7.2 * clostridium perfringens 52.0 52.0 1 PMID:202590 -1.7.7.2 * haloferax denitrificans 62.0 62.0 1 PMID:1654831 -1.7.7.2 * haloferax mediterranei 0.55 0.55 1 PMID:11731152 -1.7.7.2 * hydrogenobacter thermophilus 14.0 7.0095 2 PMID:28752517 -1.7.7.2 * leptolyngbya boryana 1020.0 662.5 2 * -1.7.7.2 * synechococcus elongatus pcc 7942 = fachb-805 790.0 30.5 3 PMID:28520412;PMID:6437330;PMID:6780511 -1.7.99.1 * caminibacter mediatlanticus 158.0 1.0 3 PMID:28388834 -1.7.99.1 * campylobacter curvus 68.0 34.015 2 PMID:28388834 -1.7.99.1 * campylobacter fetus subsp. fetus 149.0 74.535 2 PMID:28388834 -1.7.99.1 * escherichia coli 458.0 275.0 2 PMID:12374823 -1.7.99.1 * nautilia profundicola 29.0 14.505 2 PMID:28388834 -1.7.99.1 * pseudomonas aeruginosa 2.87 2.87 1 PMID:13782715 -1.7.99.1 * pyrococcus furiosus 3.7 3.7 1 PMID:19241093 -1.8.1.10 * rattus norvegicus 0.00085 0.000775 2 PMID:4662104 -1.8.1.11 * asparagus officinalis 1.082 0.214 8 PMID:1125255;PMID:180003;PMID:440099 -1.8.1.12 * crithidia fasciculata 284.0 265.5 2 PMID:3549299;PMID:3718941;PMID:8168518 -1.8.1.12 * euglena gracilis 272.0 136.0335 2 PMID:9923598 -1.8.1.12 * leishmania donovani 112.7 1.3250000000000002 8 PMID:15766869;PMID:7607216;PMID:8243474;PMID:9720880 -1.8.1.12 * naegleria fowleri 1.286 1.286 1 PMID:16620809 -1.8.1.12 * trypanosoma congolense 28.9 28.9 1 PMID:2669965 -1.8.1.12 * trypanosoma cruzi 284.0 137.0 5 PMID:10036154;PMID:3549299;PMID:3718941;PMID:7737173;PMID:8243474 -1.8.1.13 * halobacterium salinarum 28.0 26.5 2 PMID:2910862;PMID:3136140 -1.8.1.14 * borreliella burgdorferi 26.7 16.9 3 PMID:16390443 -1.8.1.15 * mycobacterium tuberculosis 3.63 3.63 1 PMID:10512639 -1.8.1.18 * thermococcus kodakarensis 14.0 9.39 2 PMID:24723088 -1.8.1.18 * thermococcus litoralis 0.35 0.35 1 PMID:18355283 -1.8.1.19 * pyrococcus furiosus 7.0 7.0 1 PMID:7961401 -1.8.1.2 * escherichia coli 10.02 6.375 2 PMID:4144254 -1.8.1.2 * methanocaldococcus jannaschii 0.0182 0.00975 2 PMID:16048999 -1.8.1.2 * saccharomyces bayanus 52.0 52.0 1 * -1.8.1.2 * saccharomyces cerevisiae 1.85 1.85 1 PMID:4384979 -1.8.1.2 * salmonella enterica subsp. enterica serovar typhimurium 81.0 81.0 1 PMID:2550423 -1.8.1.20 * rhodococcus erythropolis 3.36 3.36 1 PMID:27564089 -1.8.1.22 * nitratidesulfovibrio vulgaris 0.26 0.17 2 PMID:4725615 -1.8.1.4 * acidianus ambivalens 0.36 0.36 1 PMID:18312361 -1.8.1.4 * advenella mimigardefordensis 110.0 7.8 3 PMID:20833784 -1.8.1.4 * ascaris suum 90.2 90.2 1 PMID:507807 -1.8.1.4 * azotobacter agilis 40.0 40.0 1 PMID:4323856 -1.8.1.4 * bacillus subtilis 125.0 68.0 2 PMID:4323856;PMID:6409095 -1.8.1.4 * bombyx mori 6.65 3.4970000000000003 2 PMID:20093189 -1.8.1.4 * clostridium cylindrosporum 483.0 483.0 1 PMID:2294086 -1.8.1.4 * corynebacterium glutamicum 3.651 3.651 1 PMID:11495999 -1.8.1.4 * cupriavidus necator 100.0 4.7 3 PMID:20833784 -1.8.1.4 * escherichia coli 20.0 20.0 1 PMID:2687245 -1.8.1.4 * glycine max 83.06 83.06 1 PMID:11788775 -1.8.1.4 * halobacterium salinarum 35.0 35.0 1 * -1.8.1.4 * haloferax volcanii 24.0 19.55 4 PMID:10397837;PMID:8655478;PMID:9346289 -1.8.1.4 * homo sapiens 586.5 586.5 1 PMID:17171578 -1.8.1.4 * lathyrus oleraceus 295.0 178.5 2 PMID:8904806 -1.8.1.4 * microbacterium luteolum 59.2 30.85 2 PMID:20159566 -1.8.1.4 * mycolicibacterium smegmatis 2.43 2.43 1 PMID:9143318 -1.8.1.4 * neurospora crassa 176.8 176.8 1 PMID:4323856 -1.8.1.4 * peptostreptococcus glycinophilus 214.0 214.0 1 PMID:2294086 -1.8.1.4 * pseudomonas fluorescens 35.7 35.7 1 PMID:4323856 -1.8.1.4 * pseudomonas putida 68.0 68.0 1 PMID:3241566 -1.8.1.4 * rattus norvegicus 133.0 79.0 2 PMID:3571202;PMID:6896050 -1.8.1.4 * saccharomyces cerevisiae 843.0 843.0 1 PMID:6404748 -1.8.1.4 * serratia marcescens 34.0 34.0 1 PMID:4323856 -1.8.1.4 * streptomyces peucetius 22.4 22.4 1 PMID:19481152 -1.8.1.4 * streptomyces seoulensis 0.311 0.311 1 PMID:9858775 -1.8.1.4 * sus scrofa 210.0 3.1 12 PMID:11231302;PMID:15196936;PMID:5769986 -1.8.1.4 * synechocystis sp. 75.0 75.0 1 PMID:9217012 -1.8.1.4 * syntrophotalea carbinolica 25.7 25.7 1 PMID:1898934 -1.8.1.4 * thermoplasma acidophilum 0.012 0.012 1 * -1.8.1.4 * trypanosoma cruzi 400.0 200.1145 2 PMID:12688423;PMID:3663096 -1.8.1.5 * xanthobacter sp. 0.274 0.13905 2 PMID:10684609 -1.8.1.6 * ulva intestinalis 180.0 180.0 1 PMID:16605269 -1.8.1.7 * achromobacter starkeyi 1.18 1.18 1 PMID:4385907 -1.8.1.7 * acidithiobacillus ferrooxidans 350.0 350.0 1 * -1.8.1.7 * acidithiobacillus thiooxidans 0.331 0.331 1 * -1.8.1.7 * allochromatium vinosum 28.4 28.4 1 PMID:237878 -1.8.1.7 * anabaena sp. 249.0 247.5 2 PMID:10024475;PMID:6425264 -1.8.1.7 * badhamia polycephala 484.0 484.0 1 PMID:14563169 -1.8.1.7 * bos taurus 204.0 129.5 8 PMID:11885281;PMID:14606686;PMID:17410407;PMID:7316181;PMID:8168518 -1.8.1.7 * chlamydomonas reinhardtii 373.3 207.65 2 * -1.8.1.7 * cyberlindnera mrakii 86.9 86.9 1 PMID:8782419 -1.8.1.7 * equus caballus 248.0 248.0 1 PMID:11885281 -1.8.1.7 * escherichia coli 505.0 334.0 5 PMID:14960309;PMID:330529;PMID:3311037;PMID:6393625 -1.8.1.7 * euglena gracilis 0.246 0.246 1 PMID:9923598 -1.8.1.7 * gallus gallus 120.0 120.0 1 PMID:15858236 -1.8.1.7 * haemonchus contortus 0.118 0.118 1 PMID:28456691 -1.8.1.7 * hemicentrotus pulcherrimus 320.0 320.0 1 PMID:4407347 -1.8.1.7 * homo sapiens 314.0 34.0 17 PMID:11885281;PMID:15895687;PMID:16887253;PMID:18341267;PMID:18608753;PMID:18981569;PMID:21740105;PMID:4448168;PMID:4690607;PMID:8143;PMID:8168518;PMID:9277 -1.8.1.7 * lathyrus oleraceus 146.0 133.0 2 PMID:16665034 -1.8.1.7 * limnospira maxima 238.0 238.0 1 PMID:3089164 -1.8.1.7 * lithobates sylvaticus 124.7 124.7 1 PMID:28659307 -1.8.1.7 * medicago sativa 281.0 281.0 1 PMID:16667283 -1.8.1.7 * moniezia expansa 5.03 5.03 1 PMID:7788561 -1.8.1.7 * mus musculus 158.0 88.3 2 PMID:16387289;PMID:39757 -1.8.1.7 * oncorhynchus mykiss 27.45 27.45 1 PMID:18508412 -1.8.1.7 * onobrychis viciifolia 273.0 273.0 1 PMID:16667283 -1.8.1.7 * oryctolagus cuniculus 180.0 180.0 1 PMID:11885281 -1.8.1.7 * oryza sativa 150.0 150.0 1 * -1.8.1.7 * ovis aries 193.3 193.15 2 PMID:11885281;PMID:2737302 -1.8.1.7 * phaeodactylum tricornutum 73.3 36.879999999999995 2 PMID:19664954 -1.8.1.7 * phycomyces blakesleeanus 61.2 61.2 1 * -1.8.1.7 * plasmodium falciparum 0.047 0.023 7 PMID:12729762 -1.8.1.7 * psychrobacter sp. ant206 168.8 168.8 1 PMID:31936518 -1.8.1.7 * rattus norvegicus 269.0 152.9 8 PMID:11885281;PMID:16887253;PMID:20490902;PMID:26820767;PMID:3003504;PMID:30506659;PMID:6170346 -1.8.1.7 * rhodospirillum rubrum 2.9 2.9 1 PMID:4393659 -1.8.1.7 * saccharomyces cerevisiae 153.0 146.5 2 PMID:334266 -1.8.1.7 * setaria cervi 643.0 7.16 3 PMID:23305756;PMID:24431548 -1.8.1.7 * spinacia oleracea 246.0 177.0 2 PMID:24414099 -1.8.1.7 * sus scrofa 221.0 173.0 2 PMID:496001;PMID:955083 -1.8.1.7 * taenia crassiceps 4.9 4.9 1 PMID:14668013 -1.8.1.7 * trachemys scripta 5.5 0.9289999999999999 4 PMID:17075686 -1.8.1.7 * triticum aestivum 96.0 96.0 1 * -1.8.1.7 * xanthomonas campestris 0.045 0.041999999999999996 2 PMID:15883020 -1.8.1.9 * acidithiobacillus ferrooxidans 29.7 29.7 1 PMID:19319598 -1.8.1.9 * allochromatium vinosum 4.6 4.6 1 PMID:6373736 -1.8.1.9 * bos taurus 22.0 17.95 2 PMID:10447675 -1.8.1.9 * deinococcus radiophilus 367.7 184.23499999999999 2 PMID:21046342 -1.8.1.9 * emiliania huxleyi 150.6 36.4 3 PMID:18945673 -1.8.1.9 * escherichia coli 67.0 58.0 3 PMID:10447675;PMID:14245401;PMID:330529 -1.8.1.9 * euglena gracilis 7.32 4.12 2 PMID:26025518 -1.8.1.9 * haemonchus contortus 6.0 0.2815 4 PMID:23248236 -1.8.1.9 * homo sapiens 42.0 32.4 4 PMID:16750198;PMID:6950391;PMID:8343516;PMID:8577704 -1.8.1.9 * methanosarcina acetivorans 0.5 0.4 2 PMID:25112424 -1.8.1.9 * plasmodium falciparum 4.3 4.1 2 PMID:11022050;PMID:9368022 -1.8.1.9 * rattus norvegicus 35.0 17.7975 2 PMID:4146223;PMID:7159551 -1.8.1.9 * saccharomyces cerevisiae 103.0 103.0 1 PMID:4149839 -1.8.1.9 * spinacia oleracea 20.0 20.0 1 PMID:3190242 -1.8.1.9 * taenia crassiceps 17.5 13.9 2 PMID:14668013 -1.8.2.1 * acidithiobacillus thiooxidans 21.0 21.0 1 * -1.8.2.1 * ancylobacter novellus 327.9 233.7 2 PMID:10788424 -1.8.2.1 * paracoccus pantotrophus 0.049 0.049 1 PMID:10795683 -1.8.2.1 * paracoccus versutus 128.0 74.55 2 * -1.8.2.1 * sinorhizobium meliloti 470.0 33.4 3 PMID:24892218 -1.8.2.1 * thiobacillus thioparus 0.69 0.69 1 PMID:5438321 -1.8.2.2 * acidiphilium acidophilum 4925.0 4925.0 1 * -1.8.2.2 * acidithiobacillus ferrooxidans 6.5 5.33 2 PMID:23064330 -1.8.2.2 * alcaligenes sp. 6010.0 6010.0 1 PMID:5018699 -1.8.2.2 * allochromatium vinosum 30000.0 17900.0 2 PMID:22779704 -1.8.2.2 * nitratidesulfovibrio vulgaris 141.0 141.0 1 PMID:2993256 -1.8.2.2 * pseudomonas sp. 11.38 11.38 1 PMID:16346367 -1.8.2.2 * rhodopila globiformis 9.13 9.13 1 * -1.8.2.2 * thermithiobacillus tepidarius 316.0 5.8 4 * -1.8.2.2 * thiobacillus sp. 1149.0 1149.0 1 PMID:9082913 -1.8.2.2 * thiobacillus thioparus 146.1 146.1 1 PMID:5438323 -1.8.2.4 * rhodovulum sulfidophilum 20.2 19.2 2 PMID:8706745 -1.8.2.5 * megalodesulfovibrio gigas 41.0 41.0 1 * -1.8.3.1 * azadirachta indica 0.0322 0.0322 1 PMID:20358871 -1.8.3.1 * capra hircus 0.4036 0.4036 1 PMID:19239123 -1.8.3.1 * cassia fistula 0.0162 0.0162 1 PMID:20358871 -1.8.3.1 * gallus gallus 35.4 35.4 1 PMID:2930196 -1.8.3.1 * nicotiana tabacum 772.0 772.0 1 PMID:11598126 -1.8.3.1 * rattus norvegicus 90.0 82.5 2 PMID:408334;PMID:7161265 -1.8.3.1 * saraca indica 0.1457 0.1457 1 PMID:20358871 -1.8.3.1 * spinacia oleracea 0.1006 0.1006 1 PMID:20358871 -1.8.3.1 * sulfitobacter pontiacus 188.0 98.6 2 PMID:17705251 -1.8.3.1 * syzygium cumini 0.2032 0.2032 1 PMID:20358871 -1.8.3.1 * thermus thermophilus 56.67 28.430500000000002 2 PMID:16830073 -1.8.3.1 * vertebrata 90.0 90.0 1 PMID:7161265 -1.8.3.2 * bos taurus 103.8 17.0 4 PMID:1123323;PMID:16438804;PMID:3048213;PMID:3498875 -1.8.3.2 * oryza sativa japonica group 1.96 1.96 1 PMID:32659673 -1.8.3.2 * rattus norvegicus 9.515 9.515 1 PMID:6251889 -1.8.3.3 * penicillium sp. 272.0 272.0 1 * -1.8.3.4 * hyphomicrobium sp. 2.13 2.13 1 * -1.8.3.4 * thiobacillus thioparus 1.27 1.27 1 * -1.8.4.1 * aspergillus flavipes 289.9 289.9 1 * -1.8.4.11 * caenorhabditis elegans 0.96 0.96 1 PMID:15639227 -1.8.4.11 * clostridium sp. 4.185 0.07 3 PMID:18767149 -1.8.4.11 * escherichia coli 0.33 0.00042 8 PMID:11677230;PMID:12604343;PMID:14651971;PMID:15680228 -1.8.4.11 * mus musculus 0.238 0.16849999999999998 2 PMID:15924425 -1.8.4.11 * neisseria gonorrhoeae 0.15 0.11649999999999999 2 PMID:11938352 -1.8.4.11 * neisseria meningitidis 220.0 87.1 4 PMID:11812798 -1.8.4.11 * rattus norvegicus 0.00021 0.000205 2 PMID:12693988 -1.8.4.11 * saccharomyces cerevisiae 43.0 0.001 6 PMID:10799493;PMID:9826655 -1.8.4.11 * staphylococcus aureus 0.24 0.00024 10 PMID:11779133;PMID:14523107 -1.8.4.12 * escherichia coli 0.085 0.00031 6 PMID:11938352;PMID:12604343;PMID:14651971;PMID:15680228 -1.8.4.12 * homo sapiens 0.452 0.12 7 PMID:11938352;PMID:18452709 -1.8.4.12 * mus musculus 0.484 0.119 23 PMID:11779133;PMID:18452709;PMID:21989933 -1.8.4.12 * neisseria gonorrhoeae 0.11 0.0925 2 PMID:11938352 -1.8.4.12 * neisseria meningitidis 170.0 8.1 4 PMID:11812798 -1.8.4.12 * staphylococcus aureus 1.78 0.0012 5 PMID:11779133;PMID:14523107 -1.8.4.13 * escherichia coli 9e-05 9e-05 1 PMID:15680228 -1.8.4.13 * escherichia coli b 0.00452 0.00452 1 PMID:6999943 -1.8.4.2 * bos taurus 16000.0 382.0 6 PMID:3665436;PMID:4633484;PMID:5587960;PMID:6528979;PMID:7236203;PMID:999652 -1.8.4.2 * homo sapiens 4.1 0.03 5 PMID:10847613;PMID:6340679 -1.8.4.2 * populus sp. 70.0 68.0 2 PMID:21707412 -1.8.4.2 * rattus norvegicus 3273.0 83.0 5 PMID:4199342;PMID:4405719;PMID:4633483;PMID:6871380 -1.8.4.3 * bos taurus 0.513 0.513 1 PMID:5924646 -1.8.4.3 * rattus norvegicus 13300.0 12650.0 2 PMID:4662104 -1.8.4.4 * saccharomyces cerevisiae 61.6 61.6 1 PMID:5646485 -1.8.4.8 * escherichia coli 99.0 99.0 1 PMID:7588765 -1.8.4.8 * saccharomyces cerevisiae 44.13 44.13 1 PMID:3060034 -1.8.4.9 * arabidopsis thaliana 0.013 0.00068 8 PMID:10889258;PMID:12492831;PMID:8917599;PMID:8917600 -1.8.4.9 * brassica juncea 0.001 0.001 1 PMID:10889258 -1.8.4.9 * conticribra weissflogii 0.2 0.2 1 PMID:10889258 -1.8.4.9 * dunaliella salina 0.05 0.05 1 PMID:10889258 -1.8.4.9 * emiliania huxleyi 0.1 0.1 1 PMID:10889258 -1.8.4.9 * glycine max 0.207 0.207 1 PMID:17761201 -1.8.4.9 * isochrysis galbana 0.1 0.1 1 * -1.8.4.9 * kryptoperidinium triquetrum 0.0005 0.0005 1 PMID:10889258 -1.8.4.9 * lemna minor 0.02 0.02 1 PMID:10625629 -1.8.4.9 * pseudomonas aeruginosa 0.0023 0.0023 1 PMID:12492831 -1.8.4.9 * tetraselmis sp. 0.1 0.1 1 PMID:10889258 -1.8.4.9 * thalassiosira oceanica 0.08 0.08 1 PMID:10889258 -1.8.4.9 * ulva intestinalis 0.1 0.04 3 PMID:10889258 -1.8.5.1 * chlamydomonas reinhardtii 965.0 965.0 1 PMID:27440549 -1.8.5.1 * euglena gracilis 7.68 7.68 1 * -1.8.5.1 * homo sapiens 13.8 0.22999999999999998 8 PMID:15970797;PMID:8660320 -1.8.5.1 * ipomoea batatas 52.0 0.02632 3 PMID:18393437;PMID:18444663 -1.8.5.1 * nilaparvata lugens 1.1 1.1 1 PMID:31328816 -1.8.5.1 * oryza sativa 350.0 199.55 2 PMID:16802688 -1.8.5.1 * picea abies 1.16 0.6699999999999999 2 PMID:26684301 -1.8.5.1 * pinus bungeana 19.84 19.84 1 PMID:19903221 -1.8.5.1 * pleurotus ostreatus 9.3 9.3 1 * -1.8.5.1 * populus tomentosa 53.0 53.0 2 PMID:23661023 -1.8.5.1 * rattus norvegicus 1.31 1.03725 2 PMID:8809091 -1.8.5.1 * selaginella moellendorffii 26.15 13.184999999999999 2 PMID:26684301 -1.8.5.1 * sesamum indicum 153.0 153.0 1 PMID:17602657 -1.8.5.1 * spinacia oleracea 400.0 380.0 2 PMID:11148269 -1.8.5.1 * triticum aestivum 508.0 508.0 1 PMID:1007616 -1.8.5.1 * zea mays 19.12 15.96 4 PMID:26684301 -1.8.5.2 * acidianus ambivalens 397.0 61.650000000000006 4 PMID:15306018 -1.8.5.2 * acidithiobacillus ferrooxidans 3.16 1.605 2 PMID:23064330 -1.8.5.3 * escherichia coli 141.0 74.36 2 PMID:21357619 -1.8.5.4 * acidianus ambivalens 0.531 0.33199999999999996 4 PMID:19438211 -1.8.5.4 * acidithiobacillus ferrooxidans 20.55 10.33 2 PMID:17986789 -1.8.5.4 * allochromatium vinosum 55.4 55.4 1 PMID:9639604 -1.8.5.4 * aquifex aeolicus 71.4 37.45 2 PMID:10816041;PMID:20691146 -1.8.5.4 * chlorobaculum tepidum 12.7 12.7 1 PMID:27190141 -1.8.5.4 * homo sapiens 581.0 580.8 3 PMID:22852582;PMID:25725526 -1.8.5.4 * pseudanabaena limnetica 1.88 0.949 2 PMID:8119908 -1.8.5.4 * rhodobacter capsulatus 3.5 1.8 2 PMID:9092526 -1.8.5.4 * shouchella clausii 7.1 7.1 1 * -1.8.5.6 * aquifex aeolicus 84.2 84.2 1 PMID:32735861 -1.8.5.7 * escherichia coli 8.65 8.65 1 PMID:22955277 -1.8.5.8 * urechis unicinctus 5.12 5.12 1 PMID:20419499 -1.8.7.1 * brassica rapa 156.0 129.5 2 PMID:9339549 -1.8.7.1 * brassica rapa subsp. chinensis 61.1 61.1 1 * -1.8.7.1 * clostridium pasteurianum 0.0252 0.0252 1 PMID:4398462 -1.8.7.1 * limnospira platensis 49.0 47.2 2 * -1.8.7.1 * methanocaldococcus jannaschii 0.0182 0.00975 2 PMID:16048999 -1.8.7.1 * pyropia yezoensis 100.0 100.0 1 * -1.8.7.1 * spinacia oleracea 44.6 7.1 6 PMID:7104302 -1.8.98.1 * methanolobus tindarius 0.075 0.075 1 * -1.8.98.1 * methanosarcina barkeri 24.0 3.0 5 PMID:2121478;PMID:8174566;PMID:8477725 -1.8.98.1 * methanosarcina mazei 0.198 0.1365 2 * -1.8.98.1 * methanosarcina thermophila 200.0 126.0 2 PMID:11034998;PMID:9665708 -1.8.98.1 * methanothermobacter thermautotrophicus 29.0 10.0 3 PMID:2121478 -1.8.98.3 * methanocaldococcus jannaschii 18.2 1.3 3 PMID:16048999 -1.8.98.5 * methanococcus maripaludis 36.0 36.0 1 PMID:30010323 -1.8.98.5 * methanonatronarchaeum thermophilum 20.1 10.7 3 PMID:34435454 -1.8.98.5 * methanothermobacter marburgensis 110.0 110.0 3 PMID:21262829 -1.8.98.6 * methanococcus maripaludis 36.0 36.0 1 PMID:30010323 -1.8.98.6 * methanonatronarchaeum thermophilum 10.7 5.9 3 PMID:34435454 -1.8.98.8 * methanocaldococcus jannaschii 29.7 28.25 2 PMID:27590343 -1.8.99.2 * archaebacterium 2.39 2.39 1 * -1.8.99.2 * archaeoglobus fulgidus 1.65 1.65 1 * -1.8.99.2 * astragalus bisulcatus 0.0013 0.0013 1 PMID:15941393 -1.8.99.2 * astragalus cicer 0.0017 0.0017 1 PMID:15941393 -1.8.99.2 * astragalus crassicarpus 0.0001 0.0001 1 PMID:15941393 -1.8.99.2 * astragalus crotalariae 0.0005 0.0005 1 PMID:15941393 -1.8.99.2 * astragalus pectinatus 0.0006 0.0006 1 PMID:15941393 -1.8.99.2 * astragalus racemosus 0.0003 0.0003 1 PMID:15941393 -1.8.99.2 * astragalus tephrosioides 0.0005 0.0005 1 PMID:15941393 -1.8.99.2 * chlorobium limicola 5.75 5.75 1 PMID:235533 -1.8.99.2 * desulfobulbus propionicus 8.93 8.93 1 * -1.8.99.2 * desulfomicrobium baculatum 0.6 0.6 1 * -1.8.99.2 * desulfomicrobium orale 0.11 0.11 1 PMID:32560561 -1.8.99.2 * desulfomicrobium sp. tc4 0.134 0.134 1 PMID:32560561 -1.8.99.2 * desulfotomaculum sp. tc3 0.21 0.21 1 PMID:32560561 -1.8.99.2 * desulfovibrio desulfuricans 13.0 6.56495 2 PMID:10802060;PMID:32560561 -1.8.99.2 * desulfovibrio piger 0.34 0.34 1 PMID:32560561 -1.8.99.2 * desulfovibrio sp. 10 0.177 0.177 1 PMID:32560561 -1.8.99.2 * desulfovibrio sp. tc2 0.167 0.167 1 PMID:32560561 -1.8.99.2 * lemna minor 30.0 30.0 1 PMID:11553635 -1.8.99.2 * maridesulfovibrio salexigens 2.5 2.5 1 * -1.8.99.2 * megalodesulfovibrio gigas 6.0 6.0 1 PMID:2158885 -1.8.99.2 * mycobacterium tuberculosis 5.1 4.85 2 * -1.8.99.2 * nitratidesulfovibrio vulgaris 5.75 1.25 3 PMID:235533;PMID:32560561 -1.8.99.2 * prosthecochloris vibrioformis 13.15 13.15 1 * -1.8.99.2 * pseudomonas aeruginosa 10.3 8.05 2 PMID:10613872;PMID:16289027 -1.8.99.2 * thiobacillus thioparus 6.4 6.4 1 * -1.8.99.2 * ulva intestinalis 40.0 23.624 2 PMID:10889258;PMID:16605269 -1.9.6.1 * achromobacter sp. mmt 487.0 450.5 2 PMID:29876306 -1.9.6.1 * aliivibrio fischeri 1.484 1.484 1 PMID:13412117 -1.9.6.1 * paracoccus pantotrophus 95.0 95.0 1 PMID:8119278 -1.97.1.1 * alicycliphilus denitrificans 0.4 0.4 1 PMID:18791031 -1.97.1.1 * alicycliphilus sp. 0.4 0.35 2 PMID:18791031 -1.97.1.1 * azospira oryzae 26.4 26.4 1 PMID:10542172 -1.97.1.1 * brucella anthropi 2.31 2.31 1 PMID:31325697 -1.97.1.1 * proteus mirabilis 0.009 0.0075 2 * -1.97.1.1 * stutzerimonas chloritidismutans 42.0 42.0 5 PMID:12730181;PMID:19352644 -1.97.1.14 * enterobacter cloacae 0.5 0.277 2 PMID:16885262 -1.97.1.4 * escherichia coli 43.0 21.5085 2 PMID:10708574;PMID:6364987 -1.97.1.4 * streptococcus mutans 105.0 105.0 1 PMID:12930520 -1.97.1.9 * alcaligenes sp. 15.36 15.36 1 * -1.97.1.9 * alcaligenes sp. ckcr-6a 15.36 7.875 2 * -1.97.1.9 * enterobacter cloacae 500.0 250.145 2 PMID:14638434;PMID:16885262 -1.97.1.9 * thauera selenatis 41.4 1.6 5 PMID:10826693;PMID:1429454;PMID:9295321 -2.1.1.1 * homo sapiens 0.15 0.075014 2 PMID:21823666;PMID:29549048 -2.1.1.10 * aegilops tauschii 0.164 0.164 1 * -2.1.1.10 * brassica oleracea 0.0936 0.0054 5 PMID:17391716 -2.1.1.10 * escherichia coli 0.012 0.012 1 PMID:14445542 -2.1.1.10 * klebsiella aerogenes 0.017 0.017 1 PMID:14445542 -2.1.1.10 * rattus norvegicus 0.01215 0.00545 4 PMID:14445542;PMID:28288879 -2.1.1.10 * saccharomyces cerevisiae 1.37 0.6920000000000001 2 PMID:14445542 -2.1.1.100 * bos taurus 0.000143 0.000143 1 PMID:9894153 -2.1.1.100 * saccharomyces cerevisiae 0.755 0.755 1 PMID:20202940 -2.1.1.101 * streptomyces fradiae 0.061 0.061 1 PMID:3170601 -2.1.1.102 * streptomyces fradiae 0.25 0.25 1 PMID:3170602 -2.1.1.103 * arabidopsis thaliana 0.013 0.01075 2 PMID:11115895 -2.1.1.103 * caenorhabditis elegans 0.027 0.027 1 PMID:17313371 -2.1.1.103 * spinacia oleracea 0.189 0.189 1 * -2.1.1.104 * goniophlebium amoenum 0.05677 0.02313 17 PMID:30685696 -2.1.1.104 * haplomitrium mnioides 0.10781 0.039959999999999996 10 PMID:30634081 -2.1.1.104 * marchantia emarginata 0.22432 0.067985 10 PMID:30634081 -2.1.1.104 * marchantia paleacea 0.19117 0.046259999999999996 10 PMID:30634081 -2.1.1.104 * petroselinum crispum 0.059 0.045149999999999996 2 PMID:16667940;PMID:2499260 -2.1.1.104 * plagiochasma appendiculatum 0.12782 0.01285 19 PMID:26277769;PMID:30634081 -2.1.1.104 * populus tremuloides 0.021 0.008 3 PMID:9747797 -2.1.1.106 * streptomyces laurentii 3.9 1.3 5 PMID:26456915 -2.1.1.107 * arabidopsis thaliana 0.0091 0.0091 1 PMID:9006913 -2.1.1.107 * methanobacterium ivanovii 0.026 0.026 1 PMID:1856165 -2.1.1.107 * nitratidesulfovibrio vulgaris 0.003 0.003 1 PMID:19267692 -2.1.1.107 * pseudomonas aeruginosa 4.4e-05 4.4e-05 1 PMID:19754882 -2.1.1.107 * pseudomonas denitrificans (nom. rej.) 0.0062 0.0062 1 PMID:2546914 -2.1.1.107 * staphylococcus aureus 0.72 0.72 1 PMID:31605669 -2.1.1.109 * aspergillus parasiticus 0.061 0.052 2 PMID:16349476 -2.1.1.110 * aspergillus parasiticus 0.021 0.02025 2 PMID:10495468;PMID:8434913 -2.1.1.113 * moraxella bovis 3200.0 3200.0 1 PMID:19332813 -2.1.1.113 * moraxella cuniculi 3200.0 3200.0 1 PMID:19332813 -2.1.1.12 * hordeum vulgare 0.506 0.506 1 PMID:9765528 -2.1.1.123 * euglena gracilis 6.86e-05 6.86e-05 1 PMID:2981218 -2.1.1.127 * lathyrus oleraceus 0.3 0.3 1 PMID:8527940 -2.1.1.13 * escherichia coli 9.3 6.550000000000001 2 PMID:2853966;PMID:4154078 -2.1.1.13 * homo sapiens 2.53 1.74 4 PMID:16769880;PMID:19243433 -2.1.1.13 * sus scrofa 0.0327 0.00265 6 PMID:19474158 -2.1.1.132 * pseudomonas denitrificans (nom. rej.) 0.0057 0.0057 1 PMID:1732195 -2.1.1.136 * trichoderma longibrachiatum 0.00055 0.00055 1 PMID:12957890 -2.1.1.137 * cricetinae 2.83e-08 2.83e-08 1 PMID:9853005 -2.1.1.137 * macaca fascicularis 1.2e-09 1.2e-09 1 PMID:11684318 -2.1.1.137 * macaca mulatta 1.28e-06 6.4185e-07 2 PMID:11684318;PMID:8806872 -2.1.1.137 * macaca nemestrina 1.6e-09 1.6e-09 1 PMID:11684318 -2.1.1.137 * mus musculus 2.41e-08 9.185000000000001e-09 4 PMID:9465265 -2.1.1.137 * oryctolagus cuniculus 1.67e-06 1.67e-06 1 PMID:8605285 -2.1.1.137 * rattus norvegicus 0.00149 0.00149 1 PMID:11790780 -2.1.1.14 * escherichia coli 2.5 2.5 1 PMID:4904482 -2.1.1.14 * neurospora crassa 999.0 999.0 1 PMID:124550 -2.1.1.14 * saccharomyces cerevisiae 0.24 0.24 1 * -2.1.1.140 * berberis canadensis 0.002 0.002 1 * -2.1.1.140 * berberis koetineana 0.002 0.002 1 * -2.1.1.140 * berberis stolonifera 0.0008 0.0008 1 * -2.1.1.140 * cocculus trilobus 0.00077 0.00077 1 * -2.1.1.140 * coptis japonica 1.08 0.5485 2 PMID:11314949;PMID:11682473 -2.1.1.140 * corydalis vaginans 0.0007 0.0007 1 * -2.1.1.140 * eschscholzia californica 0.0013 0.0013 1 * -2.1.1.140 * fumaria officinalis 9.6e-05 9.6e-05 1 * -2.1.1.140 * lamprocapnos spectabilis 9.6e-05 9.6e-05 1 * -2.1.1.140 * macleaya cordata 0.00075 0.00075 1 * -2.1.1.140 * stephania delavayi 0.0001 0.0001 1 * -2.1.1.140 * thalictrum dasycarpum 0.00066 0.00066 1 * -2.1.1.140 * thalictrum flavum 0.0003 0.0003 1 * -2.1.1.140 * thalictrum flavum subsp. glaucum 0.00065 0.00065 1 * -2.1.1.140 * tinospora cordifolia 0.4 0.2018 2 * -2.1.1.140 * tinospora fragosa 0.003 0.003 1 * -2.1.1.141 * fragaria vesca 7.0 0.18 3 PMID:25046752 -2.1.1.141 * fragaria x ananassa 7.0 0.18 3 PMID:25046752 -2.1.1.146 * clarkia breweri 0.3463 0.01185 18 PMID:26378240 -2.1.1.15 * rattus norvegicus 1.8e-05 1.8e-05 1 PMID:1907579 -2.1.1.150 * medicago sativa 50.0 50.0 1 PMID:8951042 -2.1.1.151 * methanothermobacter thermautotrophicus 0.0136 0.00885 2 PMID:17567575 -2.1.1.154 * medicago sativa 0.13 0.13 1 PMID:1731632 -2.1.1.155 * dianthus caryophyllus 70.5 70.5 1 PMID:12899699 -2.1.1.156 * actinopolyspora halophila 0.34 0.18150000000000002 2 PMID:10896953 -2.1.1.156 * halorhodospira halochloris 0.52 0.175 6 PMID:10896953;PMID:11319079 -2.1.1.156 * methanohalophilus portucalensis 164.0 164.0 1 PMID:28036340 -2.1.1.157 * actinopolyspora halophila 1.0 0.645 4 PMID:10896953 -2.1.1.157 * halorhodospira halochloris 3.4 1.6400000000000001 4 PMID:10896953;PMID:11319079 -2.1.1.157 * methanohalophilus portucalensis 3.0 1.855 2 PMID:19693490 -2.1.1.158 * coffea arabica 0.32 0.32 1 PMID:9237402 -2.1.1.159 * camellia sinensis 95.0 47.545 2 PMID:10364410;PMID:10984041 -2.1.1.159 * coffea arabica 15.45 10.02 2 PMID:12527364;PMID:9237402 -2.1.1.160 * camellia sinensis 95.0 95.0 1 PMID:10364410 -2.1.1.160 * coffea arabica 3.65 3.65 1 PMID:9237402 -2.1.1.162 * methanohalophilus portucalensis 0.0046 0.0037 3 PMID:17098399 -2.1.1.165 * arabidopsis thaliana 205.0 9e-05 3 * -2.1.1.165 * batis maritima 0.3 0.3 1 PMID:9789006 -2.1.1.165 * endocladia muricata 0.000555 0.000555 1 PMID:2371563 -2.1.1.165 * pavlova pinguis 0.0018 0.0018 1 PMID:11791711 -2.1.1.165 * rhizobium sp. 5.47e-07 5.47e-07 1 PMID:11375186 -2.1.1.17 * rattus norvegicus 8.59 2.19 4 PMID:1495417;PMID:3800912 -2.1.1.19 * pseudomonas sp. 0.007 0.007 1 PMID:6023571 -2.1.1.2 * mus musculus 0.0006 0.00057 5 PMID:19021765 -2.1.1.2 * rattus norvegicus 0.16 0.13 3 PMID:3277179;PMID:6639053 -2.1.1.2 * sus scrofa 27.2 0.0038499999999999997 8 PMID:13192118;PMID:19474158;PMID:500623 -2.1.1.20 * oryctolagus cuniculus 0.7 0.6 2 PMID:15181470;PMID:4692843 -2.1.1.20 * rattus norvegicus 0.132 0.132 1 PMID:1332963 -2.1.1.21 * methyloversatilis universalis 0.1113 0.0705 3 PMID:19943898 -2.1.1.21 * pseudomonas sp. 115.0 41.6 4 PMID:1126928;PMID:3911004 -2.1.1.212 * glycyrrhiza echinata 49.2 49.2 1 PMID:12610212 -2.1.1.22 * gallus gallus 0.0005 0.0005 1 * -2.1.1.231 * dianthus caryophyllus 19590.0 19590.0 1 PMID:12899699 -2.1.1.232 * oryza sativa 0.0036 0.0036 1 PMID:22493492 -2.1.1.233 * sus scrofa 0.0046 0.0023003 2 PMID:10600115 -2.1.1.239 * streptomyces antibioticus 2.56e-06 2.56e-06 1 PMID:11514520 -2.1.1.240 * vitis vinifera 32.4 21.75 2 PMID:33919396 -2.1.1.246 * methanosarcina acetivorans 0.5657 0.5517 2 PMID:19767431 -2.1.1.246 * methanosarcina barkeri 8.0 2.0 9 PMID:10215883;PMID:10785368;PMID:11985589;PMID:8654414;PMID:8702528 -2.1.1.247 * methanosarcina barkeri 1.7 0.355 4 PMID:7635826;PMID:9006042;PMID:9732435 -2.1.1.248 * methanosarcina barkeri 0.49 0.49 1 PMID:9195968 -2.1.1.249 * methanosarcina barkeri 1.89 1.815 2 PMID:17015666;PMID:9874228 -2.1.1.25 * phanerodontia chrysosporium 101.0 101.0 1 PMID:16348886 -2.1.1.251 * methanosarcina barkeri 0.078 0.078 1 PMID:11073950 -2.1.1.26 * rattus norvegicus 0.0002 0.0002 1 PMID:14165927 -2.1.1.262 * botryococcus braunii 143.7 76.13 2 PMID:22241476 -2.1.1.263 * botryococcus braunii 7.25 7.25 1 PMID:22241476 -2.1.1.267 * catharanthus roseus 0.000219 0.000219 1 PMID:12482447 -2.1.1.267 * paeonia suffruticosa 0.165 0.096 8 PMID:26208646 -2.1.1.267 * paeonia tenuifolia 0.0023 0.0013 7 PMID:26208646 -2.1.1.273 * antirrhinum majus 0.01962 0.009836999999999999 2 PMID:11051108;PMID:12361714 -2.1.1.273 * clarkia breweri 0.0004518 0.0004518 1 PMID:10852939 -2.1.1.273 * plasmodiophora brassicae 0.0072 0.0072 1 PMID:25135243 -2.1.1.273 * populus trichocarpa 56.97 56.97 1 PMID:29237058 -2.1.1.274 * antirrhinum majus 0.000126 0.000126 1 PMID:12361714 -2.1.1.274 * clarkia breweri 0.02118 0.00078 4 PMID:10375393 -2.1.1.274 * plasmodiophora brassicae 0.009 0.009 1 PMID:25135243 -2.1.1.274 * populus trichocarpa 27.96 15.455 2 PMID:29237058 -2.1.1.278 * arabidopsis thaliana 0.00065 0.000645 2 PMID:32444138 -2.1.1.278 * populus trichocarpa 66.51 37.745000000000005 2 PMID:29237058 -2.1.1.28 * bos taurus 0.00658 0.00658 1 PMID:6847678 -2.1.1.28 * homo sapiens 1.37e-05 1.37e-05 1 PMID:21093406 -2.1.1.28 * oryctolagus cuniculus 188.0 52.55 8 PMID:623485 -2.1.1.280 * astragalus bisulcatus 1.5 0.34800000000000003 4 PMID:10026151;PMID:8706715 -2.1.1.280 * brassica oleracea 0.0051 0.0018 5 PMID:15863700 -2.1.1.283 * aspergillus terreus 3.18 3.18 1 PMID:1444712 -2.1.1.292 * streptomyces sp. 0.0194 0.0194 1 * -2.1.1.319 * homo sapiens 0.000144 0.000144 1 PMID:11724789 -2.1.1.33 * escherichia coli 3.95 3.95 1 PMID:794833 -2.1.1.34 * thermus thermophilus 0.0071 0.0071 1 PMID:7085632 -2.1.1.342 * aliivibrio fischeri 0.00114 0.00028 6 PMID:39642050 -2.1.1.342 * escherichia coli 8400.0 8400.0 1 PMID:27791000 -2.1.1.343 * streptomyces davaonensis 0.58 0.58 1 PMID:21911488 -2.1.1.35 * escherichia coli 0.46 0.00425 8 PMID:14245404;PMID:14245405;PMID:2461858;PMID:3327525;PMID:343812;PMID:374938;PMID:6997293;PMID:8054847 -2.1.1.37 * homo sapiens 0.00115 1.66e-05 3 PMID:1187340;PMID:3932345;PMID:6409149 -2.1.1.37 * mus musculus 0.0011 0.0006035000000000001 2 PMID:131936;PMID:3932345 -2.1.1.37 * oryza sativa 0.0013 0.0013 2 PMID:19401269 -2.1.1.38 * streptomyces alboniger 0.0165 0.0165 1 PMID:237215 -2.1.1.386 * mus musculus 170.0 170.0 1 PMID:17652135 -2.1.1.39 * vinca minor 0.0078 0.0078 1 PMID:1002125 -2.1.1.4 * arabidopsis thaliana 7e-07 7e-07 1 PMID:26484897 -2.1.1.4 * oryza sativa 3e-05 1.3e-05 3 PMID:22747959 -2.1.1.40 * lathyrus oleraceus 0.0078 0.0078 1 PMID:1002125 -2.1.1.402 * asterias rubens 71.6 71.6 1 PMID:9490063 -2.1.1.41 * saccharomyces cerevisiae 0.53 0.2654 2 PMID:5354959;PMID:9606964 -2.1.1.41 * trypanosoma brucei brucei 2.17e-06 1.495e-06 2 PMID:16870747 -2.1.1.41 * uromyces phaseoli 0.00124 0.00124 1 * -2.1.1.42 * glycine max 0.0029 0.0029 1 PMID:18099 -2.1.1.42 * petroselinum crispum 2.7e-05 2.7e-05 1 * -2.1.1.44 * neurospora crassa 0.0434 0.0434 1 PMID:5484456 -2.1.1.45 * angiostrongylus cantonensis 0.0003367 0.0003367 1 PMID:8001663 -2.1.1.45 * bos taurus 0.1024 0.051375000000000004 2 PMID:5017698;PMID:6990200 -2.1.1.45 * corynebacterium glutamicum 414.0 414.0 1 PMID:20595007 -2.1.1.45 * crithidia fasciculata 0.00218 0.00218 1 PMID:14696 -2.1.1.45 * cryptococcus neoformans 3.0 3.0 1 PMID:7821787 -2.1.1.45 * enterococcus faecalis 54.0 0.27 3 PMID:145246;PMID:5017698 -2.1.1.45 * escherichia coli 1.52 0.4789 6 PMID:13998281;PMID:42538;PMID:500657;PMID:6990200;PMID:786369 -2.1.1.45 * escherichia phage t2 16.0 15.0 3 PMID:4208776 -2.1.1.45 * homo sapiens 3.8 1.26 3 PMID:17297914;PMID:3341747;PMID:34155 -2.1.1.45 * kitasatospora aureofaciens 0.00652 0.00652 1 PMID:1605647 -2.1.1.45 * lacticaseibacillus casei 150.0 2.9 4 PMID:5017698;PMID:7556218;PMID:99641;PMID:99642 -2.1.1.45 * mus musculus 1.33 0.01 5 PMID:2009293;PMID:6990200;PMID:7238733 -2.1.1.45 * mycobacterium tuberculosis 210.0 210.0 2 PMID:18493582 -2.1.1.45 * plasmodium berghei 0.00235 0.00235 1 PMID:6392123 -2.1.1.45 * plasmodium falciparum 0.0255 0.0255 1 PMID:8807052 -2.1.1.45 * rattus norvegicus 0.6 0.6 1 PMID:11101356 -2.1.1.45 * saccharomyces cerevisiae 1.2 1.2 1 PMID:7028756 -2.1.1.45 * streptococcus pneumoniae 0.002 0.002 1 PMID:235997 -2.1.1.45 * strigomonas oncopelti 0.00054 0.00054 1 PMID:14696 -2.1.1.45 * tequatrovirus t4 14.45 14.45 1 PMID:4273803 -2.1.1.45 * tequintavirus t5 14.2 14.2 1 PMID:4273803 -2.1.1.45 * tetradesmus obliquus 0.0257 0.0257 1 PMID:3606123 -2.1.1.45 * trypanosoma brucei 0.0088 0.00446 2 PMID:14696;PMID:27175479 -2.1.1.45 * trypanosoma congolense 0.00014 0.00014 1 PMID:14696 -2.1.1.45 * trypanosoma cruzi 0.00156 0.00119 3 PMID:14696 -2.1.1.45 * trypanosoma lewisi 0.00038 0.00038 1 PMID:14696 -2.1.1.47 * streptomyces griseus 0.0083 0.0083 1 PMID:805896 -2.1.1.49 * bos taurus 3.3e-06 2.1e-06 3 PMID:9951405 -2.1.1.49 * oryctolagus cuniculus 0.0031 0.00035 6 PMID:3949799 -2.1.1.49 * rattus norvegicus 0.000198 3.3089999999999997e-05 4 PMID:4766261 -2.1.1.5 * gallus gallus 0.00084 0.00084 1 PMID:1819467 -2.1.1.5 * homo sapiens 940.0 50.157 4 PMID:1819467;PMID:24895213;PMID:3657557 -2.1.1.5 * ovis aries 0.000103 0.000103 1 PMID:1819467 -2.1.1.5 * rattus norvegicus 0.0187 0.0187 1 PMID:1370132 -2.1.1.5 * sus scrofa 0.0392 0.02085 2 PMID:19474158 -2.1.1.50 * catharanthus roseus 5.17e-06 2.8435e-06 2 PMID:18326827 -2.1.1.53 * nicotiana tabacum 0.051 0.0018 3 PMID:12453572 -2.1.1.54 * xanthomonas oryzae 0.11 0.11 1 PMID:27354 -2.1.1.56 * homo sapiens 0.000593 0.000593 1 PMID:956186 -2.1.1.56 * orthopoxvirus vaccinia 0.0196 0.0196 1 PMID:8195132 -2.1.1.56 * saccharomyces cerevisiae 2.35e-06 2.35e-06 1 PMID:6345158 -2.1.1.57 * orthopoxvirus vaccinia 2.33e-06 2.33e-06 1 PMID:701281 -2.1.1.59 * neurospora crassa 0.0295 0.0148945 2 PMID:196592;PMID:203592;PMID:6238220 -2.1.1.59 * saccharomyces cerevisiae 0.000117 0.000117 1 PMID:220257 -2.1.1.59 * triticum aestivum 0.000508 0.000508 1 PMID:6280753 -2.1.1.6 * homo sapiens 0.092 0.092 2 PMID:17588591 -2.1.1.6 * rattus norvegicus 2172.0 2172.0 1 PMID:1125027 -2.1.1.6 * sus scrofa domesticus 0.00107 0.00107 1 * -2.1.1.62 * homo sapiens 0.000418 0.000418 1 PMID:670176 -2.1.1.67 * homo sapiens 1.03 3.033e-05 3 PMID:18520612;PMID:6838629 -2.1.1.68 * arabidopsis thaliana 0.00609 0.00609 1 PMID:30885319 -2.1.1.68 * beta vulgaris 0.0027 0.0027 1 PMID:241400 -2.1.1.68 * glycine max 0.00546 0.00546 1 PMID:10846 -2.1.1.68 * leucaena leucocephala 0.45 0.45 1 * -2.1.1.68 * medicago sativa 0.017 0.017 1 * -2.1.1.68 * populus tremuloides 1.602 0.48 5 PMID:1368360;PMID:9747797 -2.1.1.69 * petroselinum crispum 0.041 0.041 1 * -2.1.1.69 * ruta graveolens 0.000375 5.6e-05 3 PMID:28084 -2.1.1.7 * glycine max 0.0031 0.0031 1 * -2.1.1.7 * vigna radiata var. radiata 3.2e-06 2.25e-06 2 PMID:15837705 -2.1.1.70 * petroselinum crispum 0.155 0.155 1 * -2.1.1.70 * ruta graveolens 3.3e-05 2.0150000000000002e-05 2 PMID:28084 -2.1.1.71 * rattus norvegicus 0.79 0.79 1 PMID:438165 -2.1.1.74 * enterococcus faecalis 0.1 0.1 1 PMID:106850;PMID:6768721 -2.1.1.76 * serratula tinctoria 13.8 13.8 1 PMID:15084728 -2.1.1.77 * arabidopsis thaliana 0.005028 0.00043599999999999997 8 PMID:11049748 -2.1.1.77 * bos taurus 0.012 0.012 1 PMID:4016073 -2.1.1.77 * cyberlindnera jadinii 17.01 8.7057 2 * -2.1.1.77 * daucus carota 5.7e-06 5.7e-06 1 PMID:11161058 -2.1.1.77 * escherichia coli 6.9e-06 6.9e-06 1 PMID:1860862 -2.1.1.77 * homo sapiens 0.021 0.007634999999999999 4 PMID:18381200;PMID:18419136;PMID:3167043;PMID:3355545 -2.1.1.77 * oryza sativa 2.15e-05 2.15e-05 1 PMID:11161058 -2.1.1.77 * rattus norvegicus 0.0168 0.0156 4 PMID:7663167 -2.1.1.77 * thermotoga maritima 0.156 0.0791 2 PMID:9784234 -2.1.1.77 * zea mays 1.75e-05 1.75e-05 1 PMID:11161058 -2.1.1.79 * escherichia coli 0.05 0.025000565000000002 2 PMID:15606764;PMID:380648 -2.1.1.8 * bos taurus 0.517 0.517 1 * -2.1.1.8 * cavia porcellus 25.4 8e-05 13 PMID:13804910;PMID:17706192 -2.1.1.8 * rattus norvegicus 0.004 0.004 1 * -2.1.1.8 * sus scrofa 10.4 7.4350000000000005 2 * -2.1.1.80 * bacillus subtilis 0.0024 0.001238 2 PMID:6803772;PMID:6806296 -2.1.1.80 * bos taurus 0.03 0.01715 2 PMID:6387374 -2.1.1.80 * crithidia luciliae 3.6e-06 3.6e-06 1 PMID:8542993 -2.1.1.80 * homo sapiens 0.027 0.027 1 PMID:6387374 -2.1.1.80 * salmonella enterica subsp. enterica serovar typhimurium 0.398 0.398 1 PMID:3298235 -2.1.1.82 * chrysosplenium americanum 0.011 0.011 1 PMID:3415239 -2.1.1.83 * chrysosplenium americanum 7.2 7.2 1 PMID:3994393 -2.1.1.84 * chrysosplenium americanum 2.64 2.64 1 PMID:3994393 -2.1.1.9 * arabidopsis thaliana 0.0436 0.0436 1 PMID:20376845 -2.1.1.9 * homo sapiens 3e-08 3e-08 1 PMID:22559212 -2.1.1.9 * oryza sativa 0.000966 0.000894 2 * -2.1.1.9 * phaeodactylum tricornutum 0.1043 0.1043 1 PMID:21227473 -2.1.1.9 * physcomitrium patens 0.0696 0.0696 1 PMID:22795762 -2.1.1.9 * rattus norvegicus 0.01 0.01 1 PMID:485170 -2.1.1.90 * methanosarcina barkeri 750.0 750.0 1 PMID:9057830 -2.1.1.91 * pseudomonas sp. 247.4 247.4 1 PMID:3977861 -2.1.1.94 * catharanthus roseus 0.000417 0.000417 1 PMID:18053006 -2.1.1.95 * capsicum annuum 3e-06 3e-06 1 * -2.1.1.95 * euglena gracilis 0.004 0.004 1 PMID:1420294 -2.1.1.95 * spinacia oleracea 7e-05 7e-05 1 * -2.1.1.97 * streptomyces antibioticus 3.052 3.052 1 PMID:2450873 -2.1.2.1 * corynebacterium glutamicum 0.0385 0.0385 1 PMID:19124047 -2.1.2.1 * danio rerio 5.46 5.46 1 PMID:16242955 -2.1.2.1 * escherichia coli 13.6 13.6 1 PMID:3891721 -2.1.2.1 * euglena gracilis 2.55 0.7689999999999999 4 * -2.1.2.1 * geobacillus stearothermophilus 32.4 5.0 5 PMID:10998057;PMID:12089472;PMID:18699779 -2.1.2.1 * glycine max 11.9 11.9 1 PMID:16664855 -2.1.2.1 * homo sapiens 10.0 10.0 1 PMID:8527925 -2.1.2.1 * hyphomicrobium methylovorum 7.9 7.9 1 PMID:3830156 -2.1.2.1 * leishmania donovani 1.79 1.79 1 PMID:17142057 -2.1.2.1 * macaca radiata 3.4 3.4 1 PMID:6821365 -2.1.2.1 * methanosarcina barkeri 4.3 2.4 2 PMID:15349715 -2.1.2.1 * mus musculus 9.7 9.7 1 PMID:2373684 -2.1.2.1 * oryctolagus cuniculus 15.5 10.0 3 PMID:5699057;PMID:5808700 -2.1.2.1 * ovis aries 4.8 3.7 6 PMID:10671998;PMID:10998057;PMID:12089472;PMID:7607226 -2.1.2.1 * plasmodium vivax 1.86 1.01 2 PMID:19549189 -2.1.2.1 * rattus norvegicus 7.19 7.19 1 PMID:6795186 -2.1.2.1 * spinacia oleracea 7.8 7.8 1 * -2.1.2.10 * lathyrus oleraceus 1.08 1.08 1 PMID:3143355 -2.1.2.11 * aspergillus nidulans 0.01 0.01 1 PMID:10503542 -2.1.2.11 * bacillus subtilis 0.00262 0.0025599999999999998 4 PMID:1844812 -2.1.2.11 * escherichia coli 3890.0 0.507 6 PMID:374973;PMID:776976;PMID:8096212 -2.1.2.11 * mycobacterium tuberculosis variant bovis 0.019 0.019 1 * -2.1.2.2 * escherichia coli 14.0 12.8 2 PMID:2185839;PMID:8117714 -2.1.2.2 * gallus gallus 53.6 1.294 5 PMID:13502326;PMID:4084560;PMID:6386041;PMID:666851;PMID:7354066 -2.1.2.2 * mus musculus 7.0 5.15 2 PMID:3986180;PMID:9265631 -2.1.2.3 * gallus sp. 0.856 0.44655 2 PMID:7470484 -2.1.2.3 * homo sapiens 1.19 0.595335 2 PMID:7947835;PMID:8567683 -2.1.2.3 * staphylococcus lugdunensis 0.973 0.5113 2 PMID:29063699 -2.1.2.5 * gallus gallus 10.5 10.5 1 PMID:9677386 -2.1.2.5 * rattus norvegicus 7.0 7.0 1 PMID:9677387 -2.1.2.5 * sus scrofa 43.0 41.0 2 PMID:1239299;PMID:7901203 -2.1.2.7 * pseudomonas sp. 17.4 14.25 2 PMID:14001018 -2.1.2.8 * tequatrovirus t4 5.865 4.6 5 PMID:2684015;PMID:332172;PMID:3350013;PMID:8068692 -2.1.2.9 * enterococcus faecalis 0.64 0.64 1 PMID:4206871 -2.1.2.9 * escherichia coli 35.4 1.14 3 PMID:4206871;PMID:5337045;PMID:6387369;PMID:6989606 -2.1.2.9 * euglena gracilis 0.013 0.013 1 PMID:407934 -2.1.2.9 * haemophilus influenzae 1.23 1.23 1 * -2.1.3.1 * propionibacterium freudenreichii subsp. shermanii 330.0 38.3 8 PMID:1112797;PMID:3790507;PMID:7104296;PMID:8251758;PMID:8399222 -2.1.3.1 * propionibacterium sp. 40.0 40.0 1 * -2.1.3.1 * streptomyces fradiae 0.19 0.15 3 PMID:9648221 -2.1.3.10 * malonomonas rubra 367.0 367.0 1 PMID:18251085 -2.1.3.16 * rubrobacter xylanophilus 5913.0 2956.525 2 PMID:24093154 -2.1.3.2 * bacillus subtilis 560.0 333.0 3 PMID:3937019;PMID:8535162 -2.1.3.2 * drosophila melanogaster 0.68 0.68 1 PMID:28227 -2.1.3.2 * eleusine coracana 0.8 0.8 1 PMID:453523 -2.1.3.2 * enterococcus faecalis 350.0 350.0 1 PMID:4204271;PMID:99635 -2.1.3.2 * escherichia coli 238.3 177.5 2 PMID:3902838 -2.1.3.2 * lathyrus sativus 0.7 0.7 1 PMID:453523 -2.1.3.2 * mycolicibacterium smegmatis 7900.0 7900.0 1 PMID:3342242 -2.1.3.2 * plasmodium falciparum 11.04 11.04 1 PMID:27380369 -2.1.3.2 * pseudomonas aeruginosa 450.0 450.0 1 PMID:11959858 -2.1.3.2 * pseudomonas fluorescens 3.16 3.16 1 PMID:4336369 -2.1.3.2 * pseudomonas putida 35.3 9.0 15 * -2.1.3.2 * sulfolobus acidocaldarius 29.95 29.95 1 PMID:10447693 -2.1.3.2 * trigonella foenum-graecum 0.44 0.44 1 PMID:453523 -2.1.3.2 * triticum aestivum 60.7 14.0 3 PMID:43131;PMID:7283131;PMID:9914477 -2.1.3.2 * vigna radiata var. radiata 2.7 0.35 3 PMID:453523;PMID:4611764;PMID:4658988 -2.1.3.3 * alnus glutinosa 5.56 5.56 1 * -2.1.3.3 * bacillus subtilis 265.0 265.0 1 PMID:6409880 -2.1.3.3 * bos taurus 780.0 780.0 1 PMID:4622303 -2.1.3.3 * canavalia lineata 8.31 0.907 4 PMID:11575720 -2.1.3.3 * caretta caretta 224.0 224.0 1 PMID:12108925 -2.1.3.3 * enterococcus faecalis 3200.0 1612.0 2 PMID:22363663;PMID:4622303 -2.1.3.3 * escherichia coli 2914.0 2873.5 2 PMID:4319;PMID:6393952 -2.1.3.3 * gallus gallus 77.0 77.0 1 PMID:6418730 -2.1.3.3 * homo sapiens 233.0 84.9 4 PMID:25896;PMID:893420 -2.1.3.3 * lathyrus oleraceus 157.8 148.4 2 PMID:11538003;PMID:16664120 -2.1.3.3 * lathyrus sativus 0.47 0.47 1 PMID:6895223 -2.1.3.3 * listeria monocytogenes 3.59 1.855 2 PMID:21835877 -2.1.3.3 * neurospora crassa 251.0 251.0 1 PMID:3159341 -2.1.3.3 * phaseolus vulgaris 526.0 526.0 1 PMID:9640663 -2.1.3.3 * pseudomonas aeruginosa 450.0 2.33 5 PMID:3109911;PMID:3131308 -2.1.3.3 * pseudomonas syringae 4.02 4.02 1 PMID:3592910 -2.1.3.3 * pyrococcus furiosus 0.43 0.43 1 * -2.1.3.3 * rattus norvegicus 885.0 567.5 2 PMID:489581;PMID:7356142 -2.1.3.3 * saccharolobus solfataricus 0.255 0.1875 2 * -2.1.3.3 * saccharomyces cerevisiae 561.0 198.6 3 PMID:12679340;PMID:4613551;PMID:6370999 -2.1.3.3 * salmonella enterica subsp. enterica serovar typhimurium 1901.0 1901.0 1 PMID:14923 -2.1.3.3 * spinacia oleracea 436.0 436.0 1 * -2.1.3.3 * squalus acanthias 27.1 27.1 1 PMID:2930186 -2.1.3.3 * streptococcus sp. 1000.0 1000.0 1 PMID:6034676 -2.1.3.3 * streptomyces fradiae 500.0 275.0 2 * -2.1.3.3 * sus scrofa 26.4 26.4 1 PMID:8135541 -2.1.3.3 * thermus thermophilus 3.33 3.33 1 PMID:9346304 -2.1.3.5 * streptococcus allantoicus 0.6 0.59 3 PMID:14102876 -2.1.3.6 * enterococcus faecalis 813.0 508.3 5 PMID:116850;PMID:17028272;PMID:22363663;PMID:4621632 -2.1.3.6 * listeria monocytogenes 35.6 18.085 2 PMID:21835877 -2.1.4.1 * homo sapiens 23.33 23.33 1 * -2.1.4.1 * mus musculus 0.00099 0.000485 5 PMID:19021765 -2.1.4.1 * rattus norvegicus 0.34 0.34 1 PMID:6766137 -2.1.4.1 * sus scrofa 1.25 1.057 3 PMID:14304853;PMID:19474158;PMID:3800397 -2.1.4.2 * streptomyces bikiniensis 0.17 0.17 1 PMID:1134367 -2.1.5.1 * sinomonas sp. no.22 9.8 8.1 6 PMID:27444012 -2.2.1.1 * alcaligenes faecalis 1.24 1.24 1 * -2.2.1.1 * cereibacter sphaeroides 37.0 37.0 1 PMID:15130781 -2.2.1.1 * cyberlindnera jadinii 25.0 25.0 1 PMID:21841 -2.2.1.1 * escherichia coli 50.4 0.61 4 PMID:17825449;PMID:18066500;PMID:18342970;PMID:7607225 -2.2.1.1 * homo sapiens 10.27 4.57 6 PMID:20667822;PMID:20673211;PMID:2495942;PMID:3089282;PMID:7154948 -2.2.1.1 * leishmania mexicana 1.8 1.75 2 PMID:15149284;PMID:18053578 -2.2.1.1 * moniliella megachiliensis 4.3 0.77 3 PMID:19804861 -2.2.1.1 * rattus norvegicus 1.5 1.5 1 PMID:6759853 -2.2.1.1 * saccharomyces cerevisiae 37.0 22.0 4 PMID:17681280;PMID:18070592;PMID:18186462;PMID:6759853 -2.2.1.1 * spinacia oleracea 40.0 12.0 3 PMID:8980496;PMID:9523694 -2.2.1.1 * sus scrofa 0.88 0.88 1 PMID:6759853;PMID:7448192 -2.2.1.1 * thermus thermophilus 0.407 0.407 1 PMID:36441206 -2.2.1.1 * triticum aestivum 1.6 1.6 1 PMID:24271866 -2.2.1.1 * vibrio vulnificus 0.102 0.102 1 PMID:38145310 -2.2.1.10 * methanocaldococcus jannaschii 0.033 0.033 1 PMID:18318840 -2.2.1.2 * bos taurus 3.84 3.84 1 PMID:5025625 -2.2.1.2 * carcinus maenas 0.9 0.9 1 PMID:21153090 -2.2.1.2 * clostridium acetobutylicum atcc 824 0.185 0.0643 6 PMID:19695296 -2.2.1.2 * escherichia coli 60.0 60.0 1 PMID:7592346 -2.2.1.2 * escherichia coli k-12 0.58 0.19505 6 PMID:19695296 -2.2.1.2 * fusarium oxysporum 15.0 7.65 2 * -2.2.1.2 * gluconobacter oxydans 10.1 10.1 1 PMID:14730129 -2.2.1.2 * homo sapiens 15.0 15.0 1 PMID:8549825 -2.2.1.2 * methanocaldococcus jannaschii 1.1 1.1 1 PMID:15810435 -2.2.1.2 * moniliella megachiliensis 0.6 0.6 1 PMID:19804861 -2.2.1.2 * saccharomyces cerevisiae 3.4 3.4 1 PMID:18831051 -2.2.1.2 * thermotoga maritima 42.0 25.45 2 PMID:21947648 -2.2.1.3 * [candida] boidinii 4.1 3.2 7 PMID:2280716;PMID:3997860;PMID:7074134 -2.2.1.3 * acinetobacter sp. 1.12 1.12 1 PMID:9324250 -2.2.1.4 * bacillus pumilus 0.0145 0.0145 1 * -2.2.1.5 * bos taurus 0.8 0.8 1 PMID:5418712 -2.2.1.5 * mycolicibacterium phlei 2.21 2.21 1 PMID:5003720 -2.2.1.5 * rattus norvegicus 4.1 4.1 1 PMID:2046830 -2.2.1.5 * sus scrofa 85.0 85.0 1 PMID:16742506 -2.2.1.5 * tetrahymena pyriformis 0.128 0.128 1 PMID:4203183 -2.2.1.6 * amaranthus retroflexus 12.23 11.8 2 PMID:34558160 -2.2.1.6 * anabaena azotica 0.15 0.15 1 * -2.2.1.6 * arabidopsis thaliana 7.88 7.88 1 * -2.2.1.6 * bacillus anthracis 1.5 1.5 1 * -2.2.1.6 * bacillus licheniformis 35.4 29.055 2 PMID:29026998;PMID:33193222 -2.2.1.6 * bacillus subtilis 50.94 44.52 3 PMID:234949;PMID:36368345 -2.2.1.6 * claviceps purpurea 0.135 0.135 1 * -2.2.1.6 * echinochloa crus-galli 0.2543 0.2543 1 PMID:35334143 -2.2.1.6 * enterobacter cloacae 200.0 200.0 1 * -2.2.1.6 * escherichia coli 63.6 33.15 22 PMID:11570896;PMID:15640355;PMID:16326011;PMID:19653643;PMID:20504042;PMID:21071847;PMID:36368345;PMID:38499055;PMID:6360995;PMID:9581571 -2.2.1.6 * geobacillus stearothermophilus 9.16 6.140000000000001 2 PMID:14702326 -2.2.1.6 * haemophilus influenzae 1.5 1.5 1 PMID:17718999 -2.2.1.6 * haloferax volcanii 0.0043 0.0043 1 PMID:10817907 -2.2.1.6 * hordeum vulgare 2.67 2.13 2 * -2.2.1.6 * leuconostoc lactis 267.0 208.5 2 * -2.2.1.6 * leuconostoc mesenteroides 0.844 0.844 1 * -2.2.1.6 * mycobacterium tuberculosis 42.0 6.3 12 PMID:16111681;PMID:20884690;PMID:24731825 -2.2.1.6 * neurospora crassa 0.4075 0.4075 1 PMID:4263405 -2.2.1.6 * nicotiana tabacum 5.78 1.8 4 PMID:11302749;PMID:12054619;PMID:15521822;PMID:15848141 -2.2.1.6 * pseudomonas aeruginosa 25.6 25.6 1 PMID:4201533 -2.2.1.6 * pseudomonas sp. 13.5 13.5 1 PMID:21638043 -2.2.1.6 * saccharomyces cerevisiae 49.0 23.0 4 PMID:10213630;PMID:36812944 -2.2.1.6 * salmonella enterica subsp. enterica serovar typhimurium 25.3 25.3 1 PMID:3907697 -2.2.1.6 * schoenoplectiella juncoides 2950.0 2916.5 2 * -2.2.1.6 * serratia marcescens 6.25 6.25 1 * -2.2.1.6 * thermotoga maritima 163.0 15.17 6 PMID:32958806;PMID:36368345 -2.2.1.6 * thermus thermophilus 12.6 12.6 1 PMID:26731734 -2.2.1.6 * triticum aestivum 0.0616 0.0616 1 * -2.2.1.6 * zea mays 0.66 0.66 1 PMID:16665267 -2.2.1.7 * agrobacterium tumefaciens 11.2 11.2 1 PMID:17188774 -2.2.1.7 * escherichia coli 1233.0 1200.0 2 PMID:30707333 -2.2.1.7 * plasmodium vivax 1.2 1.2 1 PMID:23772383 -2.2.1.7 * rhodobacter capsulatus 1.6 1.6 1 PMID:11114895 -2.3.1.1 * arabidopsis thaliana 9.11 9.11 1 PMID:18801197 -2.3.1.1 * danio rerio 10.64 8.057500000000001 2 PMID:18801197 -2.3.1.1 * escherichia coli 133.0 3.8449999999999998 4 PMID:16890;PMID:18801197;PMID:3911000 -2.3.1.1 * homo sapiens 13.98 0.244 10 PMID:15878741;PMID:23894642;PMID:33574402;PMID:7126172 -2.3.1.1 * maricaulis maris 62.0 6.81 3 PMID:18801197;PMID:23850694 -2.3.1.1 * mus musculus 25.56 12.78 6 PMID:12049647;PMID:18801197;PMID:33574402 -2.3.1.1 * neisseria gonorrhoeae 29.1 16.75 2 PMID:18184660;PMID:19095660 -2.3.1.1 * pseudomonas aeruginosa 79.4 79.4 1 PMID:19084009 -2.3.1.1 * rattus norvegicus 92.4 5.4900000000000006e-05 10 PMID:1929426;PMID:25771;PMID:3911000;PMID:6885773;PMID:7287652 -2.3.1.1 * saccharolobus solfataricus 0.002 0.002 2 * -2.3.1.1 * salmonella enterica subsp. enterica serovar typhimurium 0.00013 0.00013 1 PMID:3911000 -2.3.1.1 * takifugu rubripes 20.88 18.384999999999998 2 PMID:18801197 -2.3.1.1 * xanthomonas campestris 111.7 76.04 3 PMID:17425781;PMID:18801197 -2.3.1.1 * xenopus laevis 0.528 0.483 2 PMID:18801197 -2.3.1.1 * xenopus tropicalis 0.136 0.117 2 PMID:18801197 -2.3.1.101 * archaeoglobus fulgidus 1415.0 714.7 2 PMID:8481089 -2.3.1.101 * archaeoglobus lithotrophicus 0.05 0.05 1 * -2.3.1.101 * archaeoglobus profundus 0.002 0.002 1 * -2.3.1.101 * ferroglobus placidus 0.6 0.6 1 PMID:9000337 -2.3.1.101 * methanopyrus kandleri 2200.0 827.0 3 PMID:11265475;PMID:1483480 -2.3.1.101 * methanosarcina barkeri 610.0 610.0 1 PMID:2261993 -2.3.1.101 * methanothermobacter thermautotrophicus 539.0 539.0 1 * -2.3.1.102 * escherichia coli 26.0 26.0 1 PMID:3521734 -2.3.1.106 * vigna radiata var. radiata 0.000414 0.000408 2 * -2.3.1.107 * catharanthus roseus 0.0024 0.0009 13 PMID:18587132 -2.3.1.109 * burkholderia cepacia 0.007 0.007 1 * -2.3.1.11 * clostridium kluyveri 7.1 7.1 1 PMID:13221570 -2.3.1.11 * columba sp. 7.1 7.1 1 PMID:13221570 -2.3.1.110 * nicotiana tabacum 4.2 2.1078 2 PMID:9288939 -2.3.1.110 * papaver somniferum 7.76 7.76 1 PMID:10467029 -2.3.1.110 * zea mays 0.132 0.132 1 PMID:10879473 -2.3.1.111 * mycobacterium tuberculosis 0.014 0.014 1 PMID:3880746 -2.3.1.112 * arachis hypogaea 0.0002 0.0002 1 PMID:6497391 -2.3.1.113 * arachis hypogaea 0.00091 0.00091 1 PMID:6497391 -2.3.1.114 * glycine max 0.143 0.143 1 PMID:1832837 -2.3.1.115 * cicer arietinum 7.515 7.515 1 PMID:6497385 -2.3.1.115 * medicago truncatula 0.05 0.0058 3 PMID:18419782 -2.3.1.117 * escherichia coli 36.0 36.0 1 PMID:6365916 -2.3.1.118 * escherichia coli 0.67 0.265 10 PMID:10806332 -2.3.1.118 * homo sapiens 0.0183 0.00465 4 PMID:15843491 -2.3.1.118 * mesocricetus auratus 0.82 0.0042 5 PMID:3293663;PMID:3745141 -2.3.1.118 * oryctolagus cuniculus 0.034 0.034 1 PMID:7400152 -2.3.1.118 * rattus norvegicus 74.0 7.8 3 PMID:7687201 -2.3.1.118 * salmonella enterica subsp. enterica serovar typhimurium 8.72 0.5885 6 PMID:1569093;PMID:3890753;PMID:9535705 -2.3.1.12 * arabidopsis thaliana 4.09 3.99 2 PMID:10364395 -2.3.1.12 * azotobacter vinelandii 119.0 79.4 3 PMID:1554745;PMID:1935951;PMID:2653824 -2.3.1.12 * escherichia coli 47.1 40.6 2 PMID:12651118;PMID:1935951 -2.3.1.12 * homo sapiens 19.4 19.4 1 PMID:9045657 -2.3.1.12 * neisseria meningitidis 58.2 58.2 1 PMID:8958245 -2.3.1.12 * sus scrofa 19.7 19.7 1 PMID:1194249 -2.3.1.12 * syntrophotalea carbinolica 509.0 509.0 1 PMID:1898934 -2.3.1.12 * zea mays 191.0 191.0 1 PMID:10419491 -2.3.1.122 * mycolicibacterium smegmatis 0.00779 0.00779 1 PMID:3654621 -2.3.1.127 * coturnix japonica 0.0045 0.0045 1 * -2.3.1.129 * bordetella bronchiseptica 0.0011 0.001 3 PMID:11889134 -2.3.1.129 * bordetella parapertussis 0.00059 0.00030250000000000003 2 PMID:11889134 -2.3.1.129 * bordetella pertussis 0.00087 0.00057 4 PMID:11889134 -2.3.1.129 * chlamydia trachomatis 1.9e-05 1.005e-05 2 PMID:11279221 -2.3.1.129 * escherichia coli 12.3 8.3e-05 24 PMID:1495425;PMID:3549716;PMID:8366124;PMID:8824222;PMID:9242624;PMID:9829962 -2.3.1.129 * francisella tularensis subsp. novicida 0.0021 0.0021 1 PMID:27545601 -2.3.1.129 * leptospira interrogans 3.0 3.0 1 PMID:19456129 -2.3.1.129 * neisseria meningitidis 0.00325 0.000247 3 PMID:9242624 -2.3.1.129 * pseudomonas aeruginosa 0.011 6.6e-06 18 PMID:9440522;PMID:9829962 -2.3.1.13 * bos taurus 500.0 10.0 3 PMID:10630424;PMID:6276655 -2.3.1.13 * homo sapiens 13.9 4.445 6 PMID:10630424;PMID:7802672;PMID:9202629 -2.3.1.13 * ovis aries 32.0 32.0 1 PMID:7833837 -2.3.1.13 * rattus norvegicus 0.105 0.105 1 PMID:666745 -2.3.1.130 * secale cereale 0.0033 0.0033 1 * -2.3.1.131 * secale cereale 0.01 0.01 1 * -2.3.1.132 * secale cereale 0.022 0.022 1 * -2.3.1.133 * cichorium endivia 1.134 1.134 1 * -2.3.1.133 * marchantia paleacea 0.0903 0.0761 4 PMID:30691636 -2.3.1.133 * phoenix dactylifera 0.732 0.732 1 * -2.3.1.133 * plagiochasma appendiculatum 0.0888 0.07725 4 PMID:30691636 -2.3.1.133 * secale cereale 0.0056 0.0056 1 * -2.3.1.135 * bos taurus 0.1 0.1 1 PMID:2722792 -2.3.1.135 * gallus gallus 0.166 0.166 1 PMID:17014079 -2.3.1.135 * rattus norvegicus 0.0021 3.805e-05 16 PMID:2087167;PMID:8460936;PMID:9039821 -2.3.1.137 * mus musculus 0.072 0.072 1 PMID:6838215 -2.3.1.140 * coleus scutellarioides 0.044 0.044 1 PMID:17047986 -2.3.1.142 * rattus norvegicus 228.0 2.4 3 PMID:14642772;PMID:2318887 -2.3.1.144 * dianthus caryophyllus 9.48e-06 9.48e-06 1 PMID:9426598 -2.3.1.149 * homo sapiens 3.3e-06 2.05e-06 2 PMID:18587071 -2.3.1.15 * cucurbita moschata 10.0 10.0 1 PMID:11134424 -2.3.1.15 * escherichia coli 6.8 0.223 8 PMID:1860841;PMID:324973;PMID:3525559;PMID:6758857;PMID:7024733;PMID:7026564 -2.3.1.15 * helianthus annuus 0.037 0.037 1 PMID:20044264 -2.3.1.15 * lathyrus oleraceus 3.2 1.74 4 PMID:16661974;PMID:6825679 -2.3.1.15 * macrobrachium borellii 0.000322 3.42e-05 3 PMID:19130111 -2.3.1.15 * mus musculus 0.192 0.00149 17 PMID:17689486;PMID:18522808;PMID:7779773 -2.3.1.15 * rattus norvegicus 0.19 0.0016 17 PMID:14584604;PMID:1495436;PMID:17389595;PMID:17493869;PMID:4650158;PMID:4697393;PMID:7278669;PMID:7961630 -2.3.1.15 * spinacia oleracea 0.66 0.3375 2 PMID:16661974;PMID:6825679 -2.3.1.15 * theobroma cacao 0.69 0.69 1 PMID:3941071 -2.3.1.15 * umbelopsis ramanniana 1.45 1.45 1 PMID:11284717 -2.3.1.157 * escherichia coli 15.1 8.65 2 PMID:8083170 -2.3.1.157 * sulfurisphaera tokodaii 75.34 58.7 4 PMID:20400541;PMID:25567746 -2.3.1.158 * saccharomyces cerevisiae 0.002597 0.002453 5 PMID:18037386 -2.3.1.159 * ruta graveolens 14.16 7.7875 4 PMID:10217426;PMID:11054106;PMID:8148006 -2.3.1.16 * candida tropicalis 42.0 42.0 1 PMID:2575092 -2.3.1.16 * escherichia coli 1.9 1.9 1 PMID:368024 -2.3.1.16 * helianthus annuus 1988.0 352.0 3 PMID:11925043;PMID:14680958 -2.3.1.16 * pseudomonas fragi 130.0 130.0 1 PMID:2361950 -2.3.1.16 * rattus norvegicus 123.0 50.65 6 PMID:10064897;PMID:15135409;PMID:16476568;PMID:1730633;PMID:6766863 -2.3.1.16 * sus scrofa 597.0 597.0 1 PMID:344310 -2.3.1.16 * thermobifida fusca 1.85 1.5 4 PMID:38694995 -2.3.1.16 * thermus thermophilus 1082.0 1082.0 1 PMID:15786714 -2.3.1.160 * rauvolfia serpentina 2.4 2.4 1 * -2.3.1.160 * rauvolfia serpentina x rhazya stricta 99.1 99.1 1 PMID:15110859 -2.3.1.161 * aspergillus terreus 0.0109 0.0109 1 * -2.3.1.165 * penicillium griseofulvum 0.245 0.245 1 * -2.3.1.167 * taxus baccata 24.4 16.1 3 PMID:15039061 -2.3.1.168 * bos taurus 2.38 0.185 3 PMID:10989430;PMID:6746648 -2.3.1.168 * oncorhynchus mykiss 3.1 3.1 1 PMID:12031470 -2.3.1.169 * neomoorella thermoacetica 28.0 0.615 6 PMID:1624454;PMID:1995618 -2.3.1.17 * homo sapiens 70.0 70.0 1 PMID:26550943 -2.3.1.17 * mus musculus 0.0025 0.0018 3 PMID:19807691 -2.3.1.17 * rattus norvegicus 1.1e-05 8.65e-06 2 PMID:4045470 -2.3.1.172 * salvia splendens 5.17 5.17 1 PMID:11598135 -2.3.1.174 * pseudomonas sp. 11.1 11.1 1 PMID:11741862 -2.3.1.175 * hapsidospora chrysogena 30.0 7.2 5 PMID:1368946;PMID:17379148 -2.3.1.178 * halomonas elongata 50.0 50.0 1 PMID:9864317 -2.3.1.178 * halorhodospira halochloris 0.114 0.114 1 * -2.3.1.179 * escherichia coli 7.5 7.5 1 PMID:237914 -2.3.1.179 * spinacia oleracea 0.023 0.023 1 PMID:16593232 -2.3.1.18 * escherichia coli 35.3 35.3 1 PMID:14085376 -2.3.1.180 * bacillus subtilis 0.058 0.037000000000000005 2 PMID:10629181 -2.3.1.180 * cuphea wrightii 7.0 7.0 1 PMID:10600651 -2.3.1.180 * escherichia coli 5.9 2.952 2 PMID:10733911;PMID:8631920 -2.3.1.180 * escherichia coli k-12 0.024 0.012065000000000001 2 PMID:1551888 -2.3.1.180 * mycobacterium tuberculosis 0.00013 0.00013 1 PMID:10840036 -2.3.1.180 * nicotiana tabacum 0.0062 0.003153 2 PMID:11161065 -2.3.1.180 * spinacia oleracea 7.0 7.0 1 PMID:1328217 -2.3.1.180 * staphylococcus aureus 3.1e-05 1.3e-05 9 PMID:15987898 -2.3.1.180 * streptococcus pneumoniae 0.005 0.005 1 PMID:11375394 -2.3.1.181 * escherichia coli 0.54 0.54 1 PMID:15642479 -2.3.1.183 * alcaligenes faecalis 0.02 0.02 1 PMID:16347878 -2.3.1.183 * nocardia sp. 0.0221 0.0221 1 * -2.3.1.183 * rhodococcus sp. (in: high g+c gram-positive bacteria) 0.0212 0.0212 1 PMID:16347878 -2.3.1.183 * streptomyces sp. 0.0357 0.0267 2 * -2.3.1.184 * pseudomonas aeruginosa 0.0021 0.0021 1 PMID:10200267 -2.3.1.185 * brugmansia x candida 0.001 0.000875 2 PMID:10626376 -2.3.1.185 * datura stramonium 2e-05 2e-05 1 PMID:1959620 -2.3.1.186 * brugmansia x candida 0.025 0.01425 2 PMID:10626376 -2.3.1.186 * datura stramonium 12.6 6.30006 2 PMID:1959620 -2.3.1.187 * acinetobacter calcoaceticus 18.3 18.3 1 PMID:10561613 -2.3.1.187 * pseudomonas putida 2.4 1.5 2 PMID:12619701 -2.3.1.188 * allium ampeloprasum 0.0024 0.0018999999999999998 2 * -2.3.1.188 * nicotiana tabacum 0.0288 0.0248 2 * -2.3.1.188 * solanum tuberosum 0.001 0.000915 2 * -2.3.1.188 * taraxacum officinale 7.5e-05 6.15e-05 2 * -2.3.1.19 * butyrivibrio fibrisolvens 0.7 0.7 1 PMID:35524 -2.3.1.19 * clostridium acetobutylicum 1380.0 1380.0 1 PMID:2719475 -2.3.1.190 * alcaligenes eutrophus h16 2.15 2.15 2 PMID:2061286 -2.3.1.191 * escherichia coli 8.9 8.02 2 PMID:18422345 -2.3.1.192 * bos taurus 49.0 24.5255 2 PMID:2283662;PMID:457678 -2.3.1.194 * streptomyces sp. 8.9 8.9 1 PMID:20534558 -2.3.1.2 * clostridium kluyveri 5.02 5.02 1 PMID:14409246 -2.3.1.20 * acinetobacter baylyi 0.3 0.3 1 PMID:16938377 -2.3.1.20 * acinetobacter baylyi adp1 0.0543 0.0543 1 PMID:12502715 -2.3.1.20 * arachis hypogaea 0.0071 0.0071 1 PMID:16798944 -2.3.1.20 * brassica napus 0.026 0.014705 2 PMID:25687632 -2.3.1.20 * gallus gallus 0.0264 0.016149999999999998 4 PMID:10574657 -2.3.1.20 * glycine max 0.00292 0.00292 1 * -2.3.1.20 * homo sapiens 0.0035 0.0035 1 PMID:11672446 -2.3.1.20 * mus musculus 0.169 0.001505 4 PMID:11481335;PMID:12413942 -2.3.1.20 * rattus norvegicus 0.83 0.005605000000000001 8 PMID:1328797;PMID:5914;PMID:6268930;PMID:7378426;PMID:8014588;PMID:8811837 -2.3.1.20 * saccharomyces cerevisiae 0.0018 0.0018 1 PMID:226157 -2.3.1.20 * umbelopsis ramanniana 3.3 2.965 2 PMID:11481333;PMID:9354384 -2.3.1.20 * zea mays 0.119 0.119 1 PMID:11750883 -2.3.1.206 * cannabis sativa 0.0024 0.0024 1 PMID:18854334 -2.3.1.21 * bos taurus 47.5 42.0 3 PMID:3702720;PMID:6490647;PMID:7275984 -2.3.1.21 * gallus gallus 13.2 8.925 2 PMID:3593765 -2.3.1.21 * homo sapiens 39.0 0.0029 9 PMID:15579906;PMID:18306170;PMID:19049515;PMID:19937377;PMID:25781464;PMID:27123472 -2.3.1.21 * lathyrus oleraceus 0.0073 0.0073 1 * -2.3.1.21 * macrobrachium borellii 0.0565 0.0466 2 PMID:19171199 -2.3.1.21 * mus musculus 0.0062 0.00375 2 * -2.3.1.21 * oncorhynchus mykiss 0.0263 0.008199999999999999 12 PMID:18359285 -2.3.1.21 * rattus norvegicus 29.6 0.0029 41 PMID:10861226;PMID:11790778;PMID:12069851;PMID:17239528;PMID:18192268;PMID:18349115;PMID:3719003;PMID:6630173;PMID:6661210;PMID:8180250;PMID:9136891;PMID:9650584 -2.3.1.21 * sus scrofa 0.01528 0.004845 6 PMID:11790778;PMID:19049515 -2.3.1.214 * salvia splendens 0.144 0.144 1 PMID:15165190 -2.3.1.215 * iris x hollandica 1.74 1.54 3 * -2.3.1.22 * acinetobacter sp. 0.211 0.16449999999999998 2 PMID:15687201 -2.3.1.22 * arachis hypogaea 0.0159 0.0159 1 PMID:11283027 -2.3.1.22 * rattus norvegicus 1.219 1.219 1 PMID:8382031 -2.3.1.222 * salmonella enterica 50.0 29.45 2 PMID:17158662 -2.3.1.224 * salvia splendens 0.0024 0.0012023499999999998 2 PMID:15165190 -2.3.1.226 * pectobacterium carotovorum 4.0 4.0 1 PMID:14625287 -2.3.1.228 * bradyrhizobium japonicum 33.0 33.0 1 PMID:21949379 -2.3.1.23 * bos taurus 13.33 0.372 6 PMID:2729998;PMID:3421720;PMID:3707126;PMID:429375 -2.3.1.23 * helianthus annuus 0.06 0.06 1 PMID:11171182 -2.3.1.23 * homo sapiens 0.759 0.082 17 PMID:11129952;PMID:19351971;PMID:26830860 -2.3.1.23 * mus musculus 0.065 0.065 1 PMID:26830860 -2.3.1.23 * oncorhynchus mykiss 0.0038 0.0029 2 * -2.3.1.23 * rattus norvegicus 9.0 0.068 13 PMID:1495439;PMID:26830860;PMID:2835109;PMID:4774123;PMID:6268930;PMID:7161282;PMID:7357017;PMID:8611569 -2.3.1.23 * sus scrofa 0.042 0.042 1 PMID:9514659 -2.3.1.230 * pseudomonas aeruginosa 0.22 0.22 1 PMID:18728009 -2.3.1.24 * bos taurus 0.0148 0.00795 2 PMID:8593432;PMID:9655376 -2.3.1.24 * mus musculus 4.9e-05 4.9e-05 1 PMID:1317856 -2.3.1.241 * escherichia coli 80.0 41.1 2 PMID:18656959;PMID:8662613 -2.3.1.243 * escherichia coli 0.64 0.64 1 PMID:9099672 -2.3.1.247 * brevibacterium sp. 12.5 6.3025 2 PMID:7410315 -2.3.1.247 * fusobacterium nucleatum subsp. nucleatum 15.7 7.9399999999999995 2 PMID:6811551 -2.3.1.251 * escherichia coli 29.6 18.2 5 PMID:11013210 -2.3.1.251 * salmonella enterica subsp. enterica serovar typhimurium 29.6 18.2 5 PMID:11013210 -2.3.1.253 * pseudomonas fluorescens 1.03 1.03 1 PMID:28789688 -2.3.1.255 * mycobacterium tuberculosis 600.0 600.0 1 PMID:27353550 -2.3.1.256 * mycobacterium tuberculosis 1000.0 1000.0 1 PMID:27353550 -2.3.1.258 * arabidopsis thaliana 0.00138 0.00138 1 PMID:32461302 -2.3.1.258 * mycobacterium tuberculosis 1300.0 1300.0 1 PMID:27353550 -2.3.1.26 * alligator mississippiensis 0.001585 0.000816 4 * -2.3.1.26 * bos taurus 0.000169 0.000117 7 PMID:6615874 -2.3.1.26 * gallus gallus 1.78e-05 1.78e-05 1 PMID:2868756 -2.3.1.26 * homo sapiens 9560.0 0.027555000000000003 38 PMID:11684695;PMID:17497288;PMID:17950700;PMID:18340009;PMID:6113262;PMID:8798656;PMID:9219899 -2.3.1.26 * mus musculus 0.000156 0.000144 7 PMID:17872457;PMID:666765 -2.3.1.26 * oryctolagus cuniculus 0.0001042 0.0001042 1 PMID:7370290 -2.3.1.26 * platyrrhini 0.0038 0.0016250000000000001 8 PMID:11108732;PMID:9756918 -2.3.1.26 * rattus norvegicus 0.0017 6.3e-05 5 PMID:728092;PMID:8960060;PMID:9756918 -2.3.1.26 * sus scrofa 0.015 0.00754 2 PMID:7074032 -2.3.1.268 * hanseniaspora uvarum 18.71 10.99 25 PMID:40062491 -2.3.1.276 * sulfurisphaera tokodaii 40.0 39.2 2 PMID:20400541;PMID:25567746 -2.3.1.28 * bacillus pumilus 330.0 330.0 1 PMID:11342712 -2.3.1.28 * escherichia coli 251.3 190.95 2 PMID:4614890;PMID:6996733 -2.3.1.28 * flavobacterium sp. 367.7 367.7 1 PMID:3327915 -2.3.1.28 * vibrio anguillarum 71.4 71.4 1 PMID:3146569 -2.3.1.282 * mycobacterium tuberculosis 454.0 311.0 3 PMID:26271001 -2.3.1.29 * bos taurus 18.0 17.2 2 PMID:3091598;PMID:8307963 -2.3.1.29 * escherichia coli 2.76 2.76 1 PMID:3117785 -2.3.1.29 * thermus thermophilus 0.19 0.19 1 PMID:18071260 -2.3.1.293 * mycobacterium tuberculosis 0.0878 0.04675 2 PMID:11600501 -2.3.1.294 * mycobacterium tuberculosis 0.0318 0.0176 2 PMID:11600501 -2.3.1.297 * mus musculus 6e-07 6e-07 1 PMID:23591958 -2.3.1.297 * saccharomyces cerevisiae 20.68 20.68 1 PMID:15692566 -2.3.1.30 * arabidopsis thaliana 70.0 4.4 3 PMID:11168407;PMID:9692924 -2.3.1.30 * citrullus lanatus 14.7 14.7 1 PMID:7608200 -2.3.1.30 * cyanidioschyzon merolae 46.0 46.0 1 PMID:9622597 -2.3.1.30 * entamoeba histolytica 176.8 53.57 6 PMID:18851994 -2.3.1.30 * escherichia coli 71.6 1.68 3 PMID:12624753;PMID:16459339;PMID:2125278 -2.3.1.30 * leishmania major 0.0127 0.0127 1 PMID:20541568 -2.3.1.30 * mycobacterium tuberculosis 10.66 10.66 1 PMID:23483228 -2.3.1.30 * phaseolus vulgaris 0.89 0.89 1 PMID:5550822 -2.3.1.30 * salmonella enterica subsp. enterica serovar typhimurium 397.0 255.5 2 PMID:6986825 -2.3.1.30 * spinacia oleracea 205.0 205.0 1 PMID:12232109 -2.3.1.30 * staphylococcus aureus 0.00389 0.00389 1 PMID:30974158 -2.3.1.30 * vitis vinifera 25.0 25.0 1 PMID:25741355 -2.3.1.300 * bacillus subtilis 0.79 0.1585 4 PMID:10629181 -2.3.1.300 * xanthomonas campestris pv. campestris 17350.0 14350.0 2 PMID:27595587 -2.3.1.301 * mycobacterium tuberculosis 0.13 0.0063 21 PMID:10840036;PMID:16040614 -2.3.1.304 * brevundimonas sp. kh11j01 59.8 59.8 1 PMID:35533829 -2.3.1.304 * burkholderia sp. usm (jcm 15050) 0.243 0.197 2 PMID:22877240 -2.3.1.304 * cupriavidus necator 61.9 36.0 3 PMID:22369488;PMID:35533829 -2.3.1.304 * ectothiorhodospira shaposhnikovii 27.6 27.6 2 PMID:14715006 -2.3.1.304 * pseudomonas sp. sg4502 1.0 1.0 1 PMID:22249718 -2.3.1.304 * thermus thermophilus 2050.0 1025.24 2 PMID:14674696 -2.3.1.305 * acidithiobacillus ferrooxidans 0.0034 0.0007049999999999999 4 PMID:15044493 -2.3.1.305 * leptospira interrogans serogroup icterohaemorrhagiae serovar lai ipav 0.0014 0.0014 1 PMID:15044493 -2.3.1.305 * mesorhizobium loti 0.002 0.0008 3 PMID:15044493 -2.3.1.306 * candida tropicalis 0.045 0.045 1 PMID:1682209 -2.3.1.31 * [brevibacterium] flavum 0.143 0.143 1 PMID:4721772 -2.3.1.31 * neurospora sp. 3.6 1.8018 2 PMID:6037552 -2.3.1.31 * paenibacillus polymyxa 1.17 1.17 1 PMID:1126938 -2.3.1.31 * saccharomyces cerevisiae 67.4 67.4 1 PMID:3301801 -2.3.1.32 * bos taurus 1.43 1.43 1 PMID:14240571 -2.3.1.324 * ipomoea batatas 930.0 930.0 1 * -2.3.1.324 * solanum lycopersicum 22.3 22.3 1 PMID:25301886 -2.3.1.33 * oreochromis niloticus 4.3 4.3 1 PMID:7492584 -2.3.1.33 * scomber australasicus 1692.0 1692.0 1 PMID:24121108 -2.3.1.331 * chryseobacterium sp. 10.5 5.525 2 PMID:24375143 -2.3.1.332 * arabidopsis thaliana 0.0844 0.04605 2 PMID:18621978 -2.3.1.332 * petunia hybrida cv. w115 1.942 0.118 21 PMID:17323080 -2.3.1.35 * chlamydomonas reinhardtii 17.7 17.7 1 PMID:5972370 -2.3.1.35 * citrullus lanatus 4.7 4.7 1 PMID:16218965 -2.3.1.35 * corynebacterium glutamicum 0.004 0.004 1 PMID:25630515 -2.3.1.35 * geobacillus stearothermophilus 27.0 27.0 1 PMID:10931207 -2.3.1.35 * methanocaldococcus jannaschii 175.0 175.0 1 PMID:10931207 -2.3.1.35 * mus musculus 12.3 12.3 2 PMID:18801197 -2.3.1.35 * saccharomyces cerevisiae 22.0 22.0 1 PMID:7705341 -2.3.1.35 * streptomyces clavuligerus 0.087 0.087 1 PMID:11985581 -2.3.1.35 * thermotoga neapolitana 290.0 290.0 1 PMID:10931207 -2.3.1.35 * xanthomonas campestris 71.0 71.0 1 PMID:18801197 -2.3.1.36 * saccharomyces cerevisiae 2.97 2.97 1 PMID:5847960 -2.3.1.37 * cereibacter sphaeroides 2.22 1.13 11 PMID:30232811;PMID:312101;PMID:3702741;PMID:4537311;PMID:4543959;PMID:5315997 -2.3.1.37 * gallus gallus 0.58 0.58 1 PMID:3702735;PMID:6825676 -2.3.1.37 * paracoccus denitrificans 0.62 0.31185 2 PMID:4722442 -2.3.1.37 * rattus norvegicus 1.87 0.1255 6 PMID:3702735;PMID:447697;PMID:4624703;PMID:6185121;PMID:6766453;PMID:762045;PMID:8407861 -2.3.1.37 * rhodobacter capsulatus 0.49 0.425 2 PMID:39772634 -2.3.1.37 * rhodopseudomonas palustris 27.73 13.8653 2 PMID:15251194;PMID:39688068 -2.3.1.37 * saccharomyces cerevisiae 0.65 0.65 1 PMID:6381051 -2.3.1.37 * serratia plymuthica 0.35 0.35 1 * -2.3.1.37 * solanum tuberosum 0.0057 0.0057 1 PMID:4685279 -2.3.1.38 * brassica juncea 0.00019 0.00019 1 PMID:6833216 -2.3.1.38 * carthamus tinctorius 0.00023 0.000124 2 PMID:6833216;PMID:7125663 -2.3.1.38 * cuphea lutea 6.4e-05 6.4e-05 1 PMID:6833216 -2.3.1.38 * escherichia coli 0.8 0.18 4 PMID:3291856;PMID:5330116 -2.3.1.38 * euglena gracilis 0.03 0.03 1 PMID:8399328 -2.3.1.38 * lathyrus oleraceus 5e-06 5e-06 1 PMID:6833216 -2.3.1.38 * rattus norvegicus 3.81 3.22 3 PMID:9115261;PMID:9857025 -2.3.1.38 * spinacia oleracea 0.0056 0.0056 3 PMID:3517573;PMID:6833216 -2.3.1.38 * streptomyces collinus 0.022 0.022 1 PMID:11570897 -2.3.1.39 * escherichia coli 4100.0 7.04 11 PMID:1314802;PMID:29075826;PMID:4584822;PMID:5330116 -2.3.1.39 * glycine max 1.0 0.66 2 PMID:3963823 -2.3.1.39 * homo sapiens 0.14 0.12000000000000001 2 PMID:15668256 -2.3.1.39 * persea americana 9.59 9.59 1 PMID:7075600 -2.3.1.39 * rattus norvegicus 1.61 1.61 1 PMID:9115261 -2.3.1.39 * spinacia oleracea 0.0683 0.0683 1 * -2.3.1.39 * streptomyces coelicolor 780.0 780.0 1 PMID:11814333 -2.3.1.39 * trichormus variabilis 0.1541 0.1541 1 * -2.3.1.4 * aspergillus fumigatus 107.0 107.0 1 PMID:18601654 -2.3.1.4 * blastocladiella emersonii 2.41 2.41 1 PMID:4455690 -2.3.1.4 * homo sapiens 25.0 0.0379 3 PMID:18601654 -2.3.1.4 * neurospora crassa 12.21 11.955 2 PMID:13428743 -2.3.1.4 * ovis aries 0.0054 0.0054 1 PMID:14484387 -2.3.1.41 * brassica napus 0.8 0.8 1 * -2.3.1.41 * escherichia coli 14.0 6.9 8 PMID:237914;PMID:5027749;PMID:5327099;PMID:7002930 -2.3.1.41 * euglena gracilis 3.22 3.22 1 PMID:6766450 -2.3.1.41 * mycobacterium tuberculosis 0.0104 0.0081 8 PMID:16040614 -2.3.1.41 * petroselinum crispum 8.04 8.04 1 * -2.3.1.41 * plasmodium falciparum 0.105 0.105 1 PMID:16467310 -2.3.1.41 * spinacia oleracea 7.0 3.50415 2 PMID:1328217;PMID:6830245 -2.3.1.41 * streptococcus pneumoniae 0.005 0.005 1 PMID:11375394 -2.3.1.42 * cavia porcellus 3.35 1.3410000000000002 4 PMID:1495441;PMID:6639048;PMID:8380974 -2.3.1.42 * cricetulus griseus 0.00245 0.00042 3 PMID:15687349 -2.3.1.42 * homo sapiens 0.00245 0.0003505 4 PMID:10553003;PMID:15687349;PMID:8186247 -2.3.1.42 * oryctolagus cuniculus 0.0018 0.0018 1 PMID:9459311 -2.3.1.42 * rattus norvegicus 0.861 0.0056 3 PMID:3179324;PMID:6271231;PMID:9352092 -2.3.1.43 * aeromonas salmonicida 137.0 137.0 1 PMID:7061477 -2.3.1.43 * canis lupus familiaris 0.57 0.57 1 PMID:3888276 -2.3.1.43 * capra hircus 0.55 0.55 1 PMID:3888276 -2.3.1.43 * homo sapiens 53.0 0.41100000000000003 16 PMID:10428989;PMID:12975367;PMID:1770111;PMID:222331;PMID:23851343;PMID:3014276;PMID:3888276;PMID:3897772;PMID:457692;PMID:701245;PMID:7278683;PMID:7305362;PMID:7448618;PMID:9179288 -2.3.1.43 * oryctolagus cuniculus 0.56 0.56 1 PMID:3888276 -2.3.1.43 * rattus norvegicus 0.14 0.14 1 PMID:2475485 -2.3.1.43 * sus scrofa 0.59 0.47 3 PMID:3080314;PMID:3718996;PMID:3888276 -2.3.1.43 * toxoplasma gondii 0.00078 0.00078 1 PMID:26694607 -2.3.1.45 * campylobacter jejuni 0.0778 0.0172 3 PMID:16481326 -2.3.1.46 * escherichia coli 500.0 500.0 1 PMID:18978085 -2.3.1.46 * geobacillus kaustophilus 700.0 700.0 1 PMID:18978085 -2.3.1.47 * aquifex aeolicus 2.46 2.46 1 PMID:22484932 -2.3.1.47 * arabidopsis thaliana 0.09 0.09 1 PMID:16299174 -2.3.1.47 * geobacillus kaustophilus 0.071 0.071 1 PMID:22484932 -2.3.1.47 * lysinibacillus sphaericus 0.67 0.336125 2 PMID:1575677 -2.3.1.47 * pseudomonas fluorescens 0.00016 0.00016 1 * -2.3.1.47 * symbiobacterium thermophilum 0.897 0.17500000000000002 4 PMID:22484932 -2.3.1.48 * artemia nauplii 1.18e-05 9.75e-06 2 PMID:6840090 -2.3.1.48 * artemia salina 0.0014 0.0014 1 PMID:477673 -2.3.1.48 * bos taurus 0.0014 0.001275 2 PMID:22543 -2.3.1.48 * rattus norvegicus 0.00196 0.00191 2 PMID:7406506 -2.3.1.48 * saccharomyces cerevisiae 0.068 0.068 1 PMID:6389549 -2.3.1.48 * zea mays 0.0057 0.0057 1 PMID:8635608 -2.3.1.49 * klebsiella aerogenes 17.4 17.4 1 PMID:4741546 -2.3.1.5 * aeromonas hydrophila 2e-09 2e-09 1 PMID:11344150 -2.3.1.5 * anisakis simplex 2.89 2.715 2 PMID:8827040 -2.3.1.5 * bacillus anthracis 5.852 1.36 17 PMID:17511472 -2.3.1.5 * bacillus cereus 27.0 7.3 9 PMID:17368397 -2.3.1.5 * bacteroides sp. 5e-08 3.4999999999999996e-08 2 PMID:11344150 -2.3.1.5 * citrobacter amalonaticus 1e-07 4.75e-08 4 PMID:11344150 -2.3.1.5 * citrobacter farmeri 3.3e-07 5.3e-08 4 PMID:11344150 -2.3.1.5 * citrobacter freundii 1.6e-07 1.4e-07 3 PMID:11344150 -2.3.1.5 * citrobacter koseri 5.9e-07 1.64e-07 4 PMID:11344150 -2.3.1.5 * columba sp. 14.02 8.66 2 PMID:2294966;PMID:6882769 -2.3.1.5 * enterobius vermicularis 0.41 0.41 1 PMID:10413875 -2.3.1.5 * escherichia coli 0.67 5e-08 9 PMID:10226534;PMID:11344150;PMID:9516539 -2.3.1.5 * helicobacter pylori 0.91 0.75 3 PMID:11344150;PMID:9096288 -2.3.1.5 * homo sapiens 2680.0 0.010700000000000001 74 PMID:11344150;PMID:17210686;PMID:17371801;PMID:17973251;PMID:18069763;PMID:18569602;PMID:18759501;PMID:2924904;PMID:35353990 -2.3.1.5 * klebsiella oxytoca 6.1e-07 1.6e-07 3 PMID:11344150 -2.3.1.5 * klebsiella pneumoniae 3.506 0.00068 3 PMID:10226534;PMID:11344150;PMID:15340647 -2.3.1.5 * klebsiella pneumoniae subsp. ozaenae 7e-09 7e-09 1 PMID:11344150 -2.3.1.5 * klebsiella pneumoniae subsp. rhinoscleromatis 1.5e-07 7.8e-08 2 PMID:11344150 -2.3.1.5 * mesorhizobium loti 5.078 5.078 2 PMID:17658468 -2.3.1.5 * morganella morganii 2e-08 1.1000000000000001e-08 2 PMID:11344150 -2.3.1.5 * mus musculus 28.0 28.0 1 PMID:18280460 -2.3.1.5 * nocardia farcinica 87.76 0.111 24 PMID:18778714 -2.3.1.5 * oryctolagus cuniculus 0.198 0.16849999999999998 4 PMID:7329305;PMID:7400152 -2.3.1.5 * plesiomonas shigelloides 6e-09 6e-09 1 PMID:11344150 -2.3.1.5 * pseudomonas aeruginosa 73.3 2.76 57 PMID:10226534;PMID:10445164;PMID:11344150;PMID:15447630;PMID:17374145 -2.3.1.5 * salmonella enterica subsp. enterica serovar typhimurium 2.75e-05 6e-08 8 PMID:11344150 -2.3.1.5 * serratia marcescens 6e-09 4e-09 3 PMID:11344150 -2.3.1.5 * shigella flexneri 3e-09 3e-09 1 PMID:11344150 -2.3.1.5 * streptomyces griseus 1.1 0.46 5 PMID:17158669 -2.3.1.5 * tsukamurella paurometabola 3.53 1.96 4 PMID:31673919 -2.3.1.5 * vibrio cholerae serotype o1 5e-09 3e-09 2 PMID:11344150 -2.3.1.50 * cucurbita pepo 0.057 0.057 1 PMID:12232036 -2.3.1.50 * homo sapiens 0.0129 0.005875 10 PMID:19181628;PMID:20504773;PMID:2246616;PMID:30792183;PMID:9363775 -2.3.1.50 * mus musculus 4.4e-05 4.4e-05 1 PMID:9363775 -2.3.1.50 * rattus norvegicus 6.3e-05 6.3e-05 1 PMID:6421234 -2.3.1.50 * sphingomonas paucimobilis 0.7 0.404 6 PMID:11279212;PMID:30792183 -2.3.1.51 * escherichia coli 0.0008 0.0008 1 PMID:6351928 -2.3.1.51 * lathyrus oleraceus 0.0066 0.0066 1 PMID:24186288 -2.3.1.51 * mycobacterium tuberculosis 0.435 0.435 1 PMID:38676355 -2.3.1.51 * rattus norvegicus 0.44 0.44 1 PMID:6268930 -2.3.1.51 * shewanella livingstonensis 5.0 5.0 1 PMID:29415144 -2.3.1.51 * solanum tuberosum 0.0002742 1.92e-05 3 PMID:2298217 -2.3.1.51 * spinacia oleracea 0.0051 0.0051 1 * -2.3.1.52 * rattus norvegicus 0.073 0.073 1 PMID:4774123 -2.3.1.52 * tetrahymena pyriformis 0.0065 0.0065 1 PMID:402117 -2.3.1.53 * escherichia coli 75.0 75.0 1 PMID:4943352 -2.3.1.54 * escherichia coli 160.0 60.0 3 PMID:4615902;PMID:6364987 -2.3.1.54 * streptococcus mutans 12.0 12.0 1 PMID:7061379 -2.3.1.56 * homo sapiens 0.0075 0.0075 1 PMID:8353850 -2.3.1.56 * mesocricetus auratus 0.084 0.06 2 PMID:8761433 -2.3.1.56 * rattus norvegicus 0.097 0.061 2 PMID:8761433 -2.3.1.56 * salmonella enterica subsp. enterica serovar typhimurium 0.785 0.785 1 PMID:9535705 -2.3.1.57 * [candida] boidinii 2.45 2.45 1 PMID:3987688 -2.3.1.57 * ascaris suum 0.4314 0.4157 2 PMID:2320051;PMID:2775189 -2.3.1.57 * cricetulus griseus 26.0 26.0 1 PMID:12578836 -2.3.1.57 * cryptosporidium parvum 0.299 0.299 1 PMID:17289169 -2.3.1.57 * homo sapiens 45.0 0.00024 16 PMID:12803540;PMID:7873553 -2.3.1.57 * mus musculus 0.0106 0.0012 5 PMID:15737201;PMID:19473115 -2.3.1.57 * onchocerca volvulus 0.0006 0.0006 1 PMID:2320051 -2.3.1.57 * rattus norvegicus 8.102 8.102 1 PMID:6621393;PMID:7150547 -2.3.1.6 * bos taurus 142.0 142.0 1 PMID:6885755 -2.3.1.6 * drosophila melanogaster 500.0 500.0 1 PMID:6801053 -2.3.1.6 * electrophorus electricus 0.07742 0.07742 1 PMID:9679331 -2.3.1.6 * homo sapiens 50.0 50.0 1 PMID:15721778 -2.3.1.6 * rattus norvegicus 73.0 36.595 2 PMID:1548478;PMID:2606102;PMID:7430139 -2.3.1.6 * torpedo marmorata 73.0 73.0 1 PMID:2606102;PMID:7430139 -2.3.1.60 * escherichia coli 3.8 3.8 1 PMID:764855 -2.3.1.63 * oryctolagus cuniculus 0.00046 0.00046 1 PMID:1495440 -2.3.1.64 * arabidopsis thaliana 0.000187 3.0000000000000004e-05 8 PMID:19521717 -2.3.1.64 * hordeum vulgare 11.34 1.5 4 PMID:12582168 -2.3.1.65 * bos taurus 46.9 43.0 3 PMID:422567;PMID:7372637 -2.3.1.65 * canis lupus familiaris 0.0027 0.0027 1 PMID:7295754 -2.3.1.65 * homo sapiens 1.041 0.425 4 PMID:12810727;PMID:16399361;PMID:6884990 -2.3.1.65 * rattus norvegicus 3.88 2.935 2 PMID:624713 -2.3.1.67 * homo sapiens 4.1e-06 4.1e-06 1 PMID:18955040 -2.3.1.67 * mus musculus 0.00033 0.000104 3 PMID:18285344 -2.3.1.67 * rattus norvegicus 0.317 0.0023499999999999997 12 PMID:3800896;PMID:7430122;PMID:8346925;PMID:8951505 -2.3.1.7 * aspergillus niger 10.65 10.65 1 PMID:8856942 -2.3.1.7 * bos taurus 85.0 78.0 2 PMID:6639064 -2.3.1.7 * camelus dromedarius 94.0 94.0 1 PMID:8831953;PMID:8979257 -2.3.1.7 * candida albicans 8.8 0.165 6 * -2.3.1.7 * candida tropicalis 113.0 88.0 5 PMID:3665918;PMID:7084226;PMID:7165109 -2.3.1.7 * columba sp. 119.0 102.0 2 PMID:14285260;PMID:7417471 -2.3.1.7 * homo sapiens 78.75 78.75 1 PMID:2351134 -2.3.1.7 * rattus norvegicus 240.0 85.0 7 PMID:6404901;PMID:7417471 -2.3.1.7 * saccharomyces cerevisiae 200.0 200.0 1 PMID:1892891 -2.3.1.71 * bos taurus 24.0 12.5 2 PMID:2283662;PMID:457678;PMID:6276655 -2.3.1.72 * oryza sativa japonica group 0.01875 0.01809 3 PMID:29448154 -2.3.1.72 * zea mays 13.3 13.3 1 PMID:11537469 -2.3.1.73 * spinacia oleracea 0.0022 0.0014 3 * -2.3.1.74 * avena sativa 0.00918 0.00918 1 PMID:3777940 -2.3.1.74 * daucus carota 0.162 0.09040000000000001 2 PMID:4015104;PMID:4044560 -2.3.1.74 * glycine max 0.0085 0.0085 1 * -2.3.1.74 * petroselinum crispum 0.0161 0.0161 1 PMID:114396 -2.3.1.74 * phaseolus vulgaris 0.00176 0.00176 1 * -2.3.1.74 * secale cereale 0.0064 0.0064 1 * -2.3.1.74 * xanthisma gracile 0.00083 0.00083 1 * -2.3.1.75 * acinetobacter baylyi 960.0 0.84 7 PMID:16938377;PMID:22685145;PMID:23087036 -2.3.1.75 * acinetobacter baylyi adp1 2.0 0.2128 3 PMID:12502715;PMID:15687201;PMID:15691932 -2.3.1.75 * acinetobacter sp. 0.165 0.165 1 PMID:15691932 -2.3.1.75 * marinobacter nauticus 46.5 3.6 7 PMID:22685145;PMID:23087036 -2.3.1.75 * psychrobacter cryohalolentis 0.83 0.45499999999999996 2 PMID:22685145 -2.3.1.75 * rhodococcus jostii 3.37 1.745 2 PMID:22685145 -2.3.1.76 * gallus gallus 2.3e-05 2.3e-05 1 PMID:17014079 -2.3.1.76 * homo sapiens 0.00084 0.000645 2 PMID:16214399 -2.3.1.78 * homo sapiens 5.351 5.9e-05 7 PMID:16293432;PMID:8412007 -2.3.1.78 * rattus norvegicus 0.008 0.008 1 PMID:7346380 -2.3.1.79 * escherichia coli 24.8 24.8 1 PMID:1856235 -2.3.1.8 * bacillus subtilis 1371.0 1260.5 2 PMID:10423526;PMID:4201530 -2.3.1.8 * clostridium kluyveri 9100.0 7140.0 3 PMID:12980995;PMID:14087284;PMID:495955 -2.3.1.8 * fructilactobacillus sanfranciscensis 1940.0 1940.0 1 PMID:11802544 -2.3.1.8 * gottschalkia acidurici 7100.0 7100.0 1 PMID:16559158 -2.3.1.8 * limosilactobacillus fermentum 1124.0 1124.0 1 PMID:4995446 -2.3.1.8 * methanosarcina thermophila 9006.0 5737.5 2 PMID:2808380;PMID:8226623 -2.3.1.8 * neomoorella thermoacetica 12.8 12.8 1 PMID:7287757 -2.3.1.8 * rhodopseudomonas palustris 31.6 31.6 1 PMID:3790263 -2.3.1.8 * thermotoga maritima 225.0 225.0 1 PMID:10074080 -2.3.1.8 * treponema pallidum 150.0 150.0 1 PMID:37200262 -2.3.1.8 * veillonella parvula 396.0 396.0 1 PMID:5012766 -2.3.1.80 * rattus norvegicus 0.394 0.394 1 PMID:3003508 -2.3.1.81 * pseudomonas aeruginosa 34.0 21.8715 2 PMID:6281224;PMID:6803830 -2.3.1.82 * staphylococcus aureus 0.304 0.304 1 PMID:6305650 -2.3.1.84 * saccharomyces cerevisiae 190.4 97.935 2 PMID:7764365 -2.3.1.84 * saccharomyces uvarum 0.00729 0.00729 1 * -2.3.1.85 * columba sp. 1.12 0.14 3 PMID:1121292;PMID:7073698 -2.3.1.85 * corynebacterium ammoniagenes 0.37 0.33999999999999997 2 PMID:9249036 -2.3.1.85 * gallus gallus 2.6 1.25 4 PMID:6112225;PMID:6361031;PMID:6654914;PMID:9159116 -2.3.1.85 * homo sapiens 0.6 0.6 1 PMID:7567999 -2.3.1.85 * rattus norvegicus 2.68 1.61 3 PMID:9115261;PMID:9478938 -2.3.1.86 * corynebacterium ammoniagenes 0.37 0.33999999999999997 2 PMID:9249036 -2.3.1.86 * mycolicibacterium phlei 0.375 0.375 1 PMID:4698221 -2.3.1.86 * saccharomyces cerevisiae 3.0 1.5 9 PMID:322721;PMID:350874;PMID:365179;PMID:374077;PMID:4590449;PMID:7001460 -2.3.1.87 * bos taurus 4.325 4.325 1 PMID:38504591 -2.3.1.87 * clarias gariepinus 4.3e-05 3.7500000000000003e-05 4 PMID:21341536 -2.3.1.87 * oryza sativa 0.0083 0.008150000000000001 2 PMID:27121038 -2.3.1.87 * ovis aries 7.17 3.5850975 2 PMID:15477086;PMID:3298986 -2.3.1.87 * rattus norvegicus 10.57 10.57 1 PMID:15477086 -2.3.1.87 * sus scrofa 8.342 8.342 1 PMID:38504591 -2.3.1.89 * priestia megaterium 0.011 0.011 1 * -2.3.1.9 * bacopa monnieri 56.0 28.45 2 * -2.3.1.9 * bos taurus 0.05 0.05 1 PMID:13834445 -2.3.1.9 * bradyrhizobium japonicum 102.9 102.9 1 PMID:2883931 -2.3.1.9 * candida tropicalis 59.8 44.4 2 PMID:2575092;PMID:9348092 -2.3.1.9 * caulobacter vibrioides 40.98 40.98 1 PMID:1967602 -2.3.1.9 * clostridium acetobutylicum 216.0 216.0 1 PMID:16347774 -2.3.1.9 * clostridium kluyveri 115.0 115.0 1 PMID:6149704 -2.3.1.9 * dictyostelium discoideum 4.7 4.7 1 PMID:21209787 -2.3.1.9 * escherichia coli 1078.0 792.0 2 PMID:236278;PMID:9904 -2.3.1.9 * gallus gallus 203.0 203.0 1 PMID:4698219 -2.3.1.9 * halobacterium sp. 833.3 833.3 1 PMID:12013440 -2.3.1.9 * helianthus annuus 33.0 15.78 3 PMID:11925043;PMID:20011134 -2.3.1.9 * pyrobaculum neutrophilum 55.0 55.0 1 PMID:21169482 -2.3.1.9 * rattus norvegicus 100.0 68.5 2 PMID:10806397;PMID:4156910 -2.3.1.9 * rhizobium sp. 163.0 163.0 1 PMID:16535684 -2.3.1.9 * streptomyces collinus 36.6 36.6 1 PMID:11570897 -2.3.1.9 * sus scrofa 58.2 58.2 1 PMID:33667 -2.3.1.9 * thermus thermophilus 1082.0 1082.0 1 PMID:15786714 -2.3.1.9 * zoogloea ramigera 412.0 91.0 3 PMID:23736;PMID:2878927 -2.3.1.90 * quercus robur 0.0743 0.0743 1 * -2.3.1.91 * brassica napus 9.6 9.6 1 PMID:8382030 -2.3.1.91 * raphanus sativus 0.486 0.486 1 * -2.3.1.91 * sinapis alba 0.258 0.258 1 * -2.3.1.92 * raphanus sativus 0.528 0.528 1 PMID:24178050 -2.3.1.93 * lupinus albus 2.18 0.44 3 PMID:15659437;PMID:8195240 -2.3.1.95 * arachis hypogaea 0.0035 0.0035 1 PMID:6427224 -2.3.1.97 * arabidopsis thaliana 0.00115 0.00115 1 PMID:10734119 -2.3.1.97 * bos taurus 0.1 0.096 3 PMID:1487006;PMID:9879658 -2.3.1.97 * candida albicans 0.000149 8.649999999999999e-05 2 PMID:1569105 -2.3.1.97 * homo sapiens 0.248 3.7e-05 4 PMID:8601412;PMID:8717441;PMID:9506952 -2.3.1.97 * mus musculus 7.6e-06 4.85e-06 2 PMID:1915371 -2.3.1.97 * rattus norvegicus 0.00076 2.9e-06 3 PMID:1915371;PMID:3123478 -2.3.1.97 * saccharomyces cerevisiae 0.15 0.0072 3 PMID:1915371;PMID:2033063;PMID:2198291;PMID:3100524 -2.3.1.97 * triticum aestivum 0.00032 0.00032 1 PMID:3123489 -2.3.1.98 * solanum lycopersicum 1.45 1.45 1 PMID:20880851 -2.3.1.99 * bambusa multiplex 9.0 5.2 4 PMID:36305861 -2.3.1.99 * malus sylvestris 0.37 0.37 1 * -2.3.1.99 * marchantia paleacea 0.0903 0.0761 4 PMID:30691636 -2.3.1.99 * nicotiana tabacum 1.08 1.08 1 PMID:15107863 -2.3.1.99 * plagiochasma appendiculatum 0.0888 0.07735 4 PMID:30691636 -2.3.1.99 * secale cereale 0.0042 0.0042 1 * -2.3.1.99 * solanum tuberosum 16.74 16.74 1 * -2.3.2.10 * weissella viridescens 276.0 276.0 1 * -2.3.2.13 * badhamia polycephala 8.8 4.402500000000001 2 PMID:1348244;PMID:9792706 -2.3.2.13 * bos taurus 0.3 0.3 1 * -2.3.2.13 * cavia porcellus 17.0 1.2 7 PMID:14711514;PMID:1968007;PMID:2868387;PMID:5928192;PMID:6133482 -2.3.2.13 * euphausia superba 53.518 53.518 1 PMID:28490058 -2.3.2.13 * glycine max 0.16 0.16 1 PMID:8670274 -2.3.2.13 * homo sapiens 91.7 0.156 13 PMID:15694843;PMID:23085087;PMID:2575900;PMID:2868387;PMID:2889472;PMID:2889725;PMID:2900016 -2.3.2.13 * nemipterus sp. 3.92 3.92 1 * -2.3.2.13 * oreochromis niloticus 197.0 197.0 1 * -2.3.2.13 * ovis aries 0.092 0.0486 2 PMID:9255969 -2.3.2.13 * sardina pilchardus 357.14 357.14 1 PMID:40006172 -2.3.2.13 * streptomyces hygroscopicus 7.6 0.54 3 PMID:29229872 -2.3.2.13 * streptomyces mobaraensis 39.2 27.2 3 PMID:11141280;PMID:20521043 -2.3.2.13 * streptomyces sp. 22.6 22.6 1 * -2.3.2.13 * streptomyces sp. tyq1024 63.75 63.75 1 PMID:32325545 -2.3.2.13 * zea mays 0.889 0.6045 2 PMID:30868593 -2.3.2.14 * lathyrus oleraceus 0.245 0.245 1 * -2.3.2.15 * arabidopsis thaliana 30.0 18.4 9 PMID:20074807;PMID:26018077 -2.3.2.15 * solanum lycopersicum 0.0055 0.0055 1 * -2.3.2.2 * allium cepa 11.29 11.29 1 PMID:15721943 -2.3.2.2 * ascaris suum 1009.0 1009.0 1 PMID:8784770 -2.3.2.2 * bacillus amyloliquefaciens 55.0 36.4 2 PMID:28120195;PMID:31747270 -2.3.2.2 * bacillus licheniformis 250.09 51.9 5 PMID:18810539;PMID:19340483;PMID:27259644;PMID:28120195;PMID:29162462 -2.3.2.2 * bacillus subtilis 100.0 62.9 7 PMID:1371053;PMID:28120195;PMID:28414108 -2.3.2.2 * bacillus velezensis 16.1 16.1 1 PMID:28120195 -2.3.2.2 * bos taurus 956.0 681.5 2 PMID:32176;PMID:6135696 -2.3.2.2 * escherichia coli 6.8 4.775 4 PMID:17094029;PMID:18720502;PMID:19788059;PMID:2877974 -2.3.2.2 * helicobacter pylori 3.59 3.59 1 PMID:16672227 -2.3.2.2 * homo sapiens 800.0 120.0 11 PMID:1674218;PMID:18197;PMID:18198;PMID:19463;PMID:2568988;PMID:4442;PMID:6112969;PMID:6148333;PMID:7816801;PMID:8095866;PMID:8827453 -2.3.2.2 * lepidochelys kempii 2213.0 2213.0 1 PMID:7599989 -2.3.2.2 * mus musculus 21.2 21.2 1 PMID:36916 -2.3.2.2 * oncornavirus 6.0 6.0 1 PMID:36916 -2.3.2.2 * ovis aries 510.0 510.0 1 PMID:1275 -2.3.2.2 * penicillium roqueforti 8.9 8.9 1 * -2.3.2.2 * phaseolus vulgaris 3.1 3.1 1 PMID:6030345 -2.3.2.2 * proteus mirabilis 16.0 16.0 1 PMID:6112969;PMID:6148333 -2.3.2.2 * pseudomonas nitroreducens 7.1 7.1 1 PMID:30507352 -2.3.2.2 * raphanus sativus 1.73 1.035 4 PMID:16495652 -2.3.2.2 * rattus norvegicus 1320.0 134.75 20 PMID:18584486;PMID:2859051;PMID:2868390;PMID:39603;PMID:4151995;PMID:6111348;PMID:6127596;PMID:6128031;PMID:6152628 -2.3.2.2 * saccharomyces cerevisiae 120.0 120.0 1 * -2.3.2.2 * solanum lycopersicum 24.03 15.39 4 PMID:10759537 -2.3.2.2 * toona sinensis 8.92 8.92 1 * -2.3.2.2 * treponema denticola 158.4 158.4 1 PMID:12496183 -2.3.2.24 * oryctolagus cuniculus 0.81 0.81 1 PMID:2550069 -2.3.2.3 * bacillus subtilis 3.26e-06 1.43e-06 3 PMID:18241797 -2.3.2.5 * homo sapiens 18.7 18.7 1 PMID:12196024 -2.3.2.5 * mus musculus 11.2 11.2 1 PMID:16201766 -2.3.2.7 * mycobacterium tuberculosis 0.0245 0.0245 1 * -2.3.2.8 * oryctolagus cuniculus 1.3 0.05935 4 PMID:2841321;PMID:5416661;PMID:5811819;PMID:6387371 -2.3.2.8 * sus scrofa 7.6 4.949999999999999 2 PMID:6442545;PMID:6671977 -2.3.2.9 * agaricus bisporus 1.4 1.4 1 PMID:14209959 -2.3.3.1 * nitrobacter winogradskyi 24.0 24.0 1 * -2.3.3.1 * rattus norvegicus 0.076 0.076 1 PMID:10775554 -2.3.3.1 * solanum lycopersicum 108.0 108.0 1 * -2.3.3.1 * yarrowia lipolytica 161.2 161.2 1 * -2.3.3.10 * blattella germanica 40.0 40.0 1 PMID:9304791 -2.3.3.10 * bos taurus 0.88 0.88 1 PMID:2860895 -2.3.3.10 * brassica juncea 0.1 0.1 1 PMID:15233626 -2.3.3.10 * enterococcus faecalis 10.0 10.0 1 PMID:12107122 -2.3.3.10 * gallus gallus 1.0 0.00958 19 PMID:2862566;PMID:4693519;PMID:7775873;PMID:804485;PMID:8099358 -2.3.3.10 * homo sapiens 0.76 0.76 1 PMID:7913309 -2.3.3.10 * mus musculus 0.057 0.046 2 PMID:18313239 -2.3.3.10 * saccharomyces cerevisiae 2.1 2.05 2 PMID:4561617;PMID:4561618 -2.3.3.12 * escherichia coli 4.8 4.8 1 PMID:14085361 -2.3.3.13 * bacteroides fragilis 0.0086 0.0086 1 PMID:6798949 -2.3.3.13 * clostridium formicaceticum 0.0024 0.0024 1 PMID:6798949 -2.3.3.13 * clostridium pasteurianum 1.413 0.70745 2 PMID:6798949 -2.3.3.13 * cupriavidus necator 12.05 12.05 1 PMID:16576 -2.3.3.13 * neomoorella thermoacetica 0.0089 0.0089 1 PMID:6798949 -2.3.3.13 * saccharomyces cerevisiae 7.1 4.34 2 PMID:3071716;PMID:325001;PMID:5079061 -2.3.3.13 * salmonella enterica subsp. enterica serovar typhimurium 14.5 8.085 2 PMID:4943722;PMID:4976555 -2.3.3.14 * aspergillus fumigatus 0.8 0.8 1 PMID:20363898 -2.3.3.14 * azotobacter vinelandii 0.657 0.657 1 PMID:9294461 -2.3.3.14 * thermus thermophilus 0.0415 0.005549999999999999 8 PMID:19996101 -2.3.3.15 * pseudomonas aeruginosa 0.4 0.4 1 PMID:6774766 -2.3.3.15 * roseovarius nubinhibens 0.08 0.08 1 PMID:20150239 -2.3.3.16 * acinetobacter calcoaceticus subsp. anitratus 235.0 88.0 3 PMID:1524432;PMID:4211224 -2.3.3.16 * arabidopsis thaliana 0.23 0.11511500000000001 2 PMID:11100775 -2.3.3.16 * aspergillus nidulans 41.5 41.5 1 PMID:10712680 -2.3.3.16 * aspergillus niger 79.0 79.0 1 PMID:10689162 -2.3.3.16 * azotobacter vinelandii 523.0 287.65 2 PMID:4211224 -2.3.3.16 * bacillus subtilis 2.6 2.6 1 PMID:4211224 -2.3.3.16 * cicer arietinum 0.87 0.87 1 PMID:10648103 -2.3.3.16 * citrullus lanatus 0.764 0.764 1 PMID:24226535 -2.3.3.16 * corynebacterium glutamicum 1.26 1.125 2 PMID:20630483 -2.3.3.16 * cupriavidus necator 64.0 64.0 1 PMID:9385140 -2.3.3.16 * daucus carota 0.78 0.39039 2 PMID:11100775 -2.3.3.16 * dictyostelium discoideum 471.7 471.7 1 PMID:195530 -2.3.3.16 * drosophila melanogaster 112.5 112.5 1 PMID:9387145 -2.3.3.16 * escherichia coli 120.0 62.6 3 PMID:1524432;PMID:6339275 -2.3.3.16 * halobacterium salinarum 27.45 13.750499999999999 2 PMID:1180893 -2.3.3.16 * haloferax volcanii 40.0 25.8 3 PMID:10397837;PMID:1321743 -2.3.3.16 * heliocidaris crassispina 1190.0 1190.0 1 PMID:457631 -2.3.3.16 * komagataeibacter europaeus 230.0 230.0 1 PMID:8997706 -2.3.3.16 * lathyrus oleraceus 664.2 664.2 1 PMID:16666610 -2.3.3.16 * mesorhizobium ciceri 1.25 1.25 1 PMID:10648103 -2.3.3.16 * methanosarcina barkeri 0.002 0.002 1 * -2.3.3.16 * methylorubrum extorquens 24.0 24.0 1 PMID:9113733 -2.3.3.16 * natronobacterium gregoryi 0.014 0.014 1 * -2.3.3.16 * natronomonas pharaonis 0.026 0.026 1 * -2.3.3.16 * nitrosomonas sp. 288.0 288.0 1 * -2.3.3.16 * priestia megaterium 21.6 21.6 1 PMID:6412681 -2.3.3.16 * pseudomonas aeruginosa 11.5 3.0100000000000002 6 * -2.3.3.16 * pseudomonas sp. 102.7 102.7 1 PMID:206330 -2.3.3.16 * pyrococcus furiosus 112.5 71.25 2 PMID:8532683 -2.3.3.16 * rhodothermus marinus 60.0 44.0 2 PMID:11878562 -2.3.3.16 * saccharolobus solfataricus 18.0 18.0 1 PMID:3130075 -2.3.3.16 * saccharomyces cerevisiae 213.0 141.5 2 PMID:10931186;PMID:1897942 -2.3.3.16 * solanum tuberosum 0.02 0.02 1 PMID:7580855 -2.3.3.16 * sulfolobus acidocaldarius 53.0 14.0 3 * -2.3.3.16 * talaromyces trachyspermus 50.0 50.0 1 PMID:4681059 -2.3.3.16 * tetrahymena pyriformis 35.1 35.1 1 PMID:8537311 -2.3.3.16 * thermoplasma acidophilum 51.4 18.8 5 PMID:10964687;PMID:8694816 -2.3.3.16 * urocitellus richardsonii 31.714 11.4647 4 PMID:34186087 -2.3.3.18 * streptomyces hygroscopicus 546.8 546.8 1 PMID:3170341 -2.3.3.21 * geobacter sulfurreducens 0.0074 0.0027500000000000003 4 PMID:18245290 -2.3.3.21 * leptospira interrogans 9.4 2.5149999999999997 26 PMID:15292141;PMID:18498255 -2.3.3.21 * methanocaldococcus jannaschii 2.87 2.87 1 PMID:9864346 -2.3.3.21 * rhodospirillum rubrum 0.058 0.0245 4 * -2.3.3.21 * thermoanaerobacter sp. x514 0.027 0.027 1 PMID:19525270 -2.3.3.3 * clostridium acidi-urici 5.5 5.5 1 * -2.3.3.3 * clostridium kluyveri 1.3 1.3 1 PMID:17400742 -2.3.3.3 * syntrophus aciditrophicus 1.2 0.96 2 PMID:23378508 -2.3.3.4 * talaromyces trachyspermus 1.25 1.25 1 PMID:4774124 -2.3.3.5 * aspergillus fumigatus 48.0 0.085 5 PMID:16008561;PMID:17973657 -2.3.3.5 * aspergillus nidulans 41.5 7.35 4 PMID:10712680 -2.3.3.5 * aspergillus niger 0.012 0.012 1 * -2.3.3.5 * citeromyces matritensis 0.009 0.009 1 * -2.3.3.5 * cryptococcus neoformans 0.008 0.008 1 * -2.3.3.5 * cutaneotrichosporon curvatum 0.014 0.014 1 * -2.3.3.5 * cyberlindnera saturnus 0.017 0.017 1 * -2.3.3.5 * debaryomyces hansenii 0.016 0.016 1 * -2.3.3.5 * diutina catenulata 0.012 0.006 5 * -2.3.3.5 * escherichia coli 0.33 0.33 1 PMID:9325432 -2.3.3.5 * fusarium solani 19.55 19.3 2 PMID:19661181 -2.3.3.5 * fusarium verticillioides 36.6 25.955000000000002 2 PMID:19661181 -2.3.3.5 * kluyveromyces marxianus 0.056 0.049 2 * -2.3.3.5 * lipomyces starkeyi 0.116 0.116 1 * -2.3.3.5 * metschnikowia pulcherrima 0.027 0.027 1 * -2.3.3.5 * mucor rouxianus 0.011 0.011 1 * -2.3.3.5 * neurospora crassa 0.018 0.018 1 * -2.3.3.5 * ogataea angusta 0.025 0.025 1 * -2.3.3.5 * priceomyces haplophilus 0.065 0.065 1 * -2.3.3.5 * rhizopus microsporus var. chinensis 0.01 0.01 1 * -2.3.3.5 * rhodothermus marinus 28.0 28.0 1 PMID:11878562 -2.3.3.5 * saccharomyces cerevisiae 0.007 0.007 1 * -2.3.3.5 * saccharomycopsis fibuligera 0.016 0.0155 2 * -2.3.3.5 * schwanniomyces polymorphus 0.038 0.038 1 * -2.3.3.5 * starmerella gropengiesseri 0.023 0.023 1 * -2.3.3.5 * starmerella magnoliae 0.086 0.086 1 * -2.3.3.5 * torulaspora delbrueckii 0.016 0.016 1 * -2.3.3.5 * ustilago crus-galli 0.053 0.053 1 * -2.3.3.5 * ustilago utriculosa 0.014 0.014 1 * -2.3.3.5 * vanrija humicola 0.027 0.027 1 * -2.3.3.5 * wickerhamiella pararugosa 0.022 0.022 1 * -2.3.3.5 * wickerhamomyces anomalus 0.018 0.018 1 * -2.3.3.5 * yarrowia lipolytica 0.623 0.032 14 PMID:7117251 -2.3.3.7 * pseudomonas aeruginosa 0.009 0.009 1 PMID:14080804 -2.3.3.8 * aspergillus nidulans 19.6 19.6 1 PMID:12009400;PMID:9450098 -2.3.3.8 * chlorobaculum tepidum 5.6 5.6 1 PMID:9244275 -2.3.3.8 * homo sapiens 2.0 2.0 1 PMID:10653665 -2.3.3.8 * hydrogenobacter thermophilus 26.7 26.7 1 PMID:2703459 -2.3.3.8 * lipomyces starkeyi 0.922 0.922 1 * -2.3.3.8 * phaffia rhodozyma 2.0 1.018 2 PMID:26122278 -2.3.3.8 * rattus norvegicus 13.6 8.3 2 PMID:6335031;PMID:7665595 -2.3.3.9 * bacillus sp. (in: firmicutes) 26.9 26.9 1 PMID:28311 -2.3.3.9 * candida tropicalis 18.9 18.9 1 PMID:3718151 -2.3.3.9 * colwellia maris 69.6 69.6 1 PMID:11440123 -2.3.3.9 * corynebacterium glutamicum 28.6 28.6 1 PMID:7812449 -2.3.3.9 * escherichia coli 36.1 35.2 2 PMID:12930982;PMID:28311 -2.3.3.9 * euglena gracilis 5.19 2.74 2 PMID:15964777;PMID:28738 -2.3.3.9 * mycobacterium tuberculosis 6.0 6.0 1 PMID:12393860 -2.3.3.9 * paracoccidioides brasiliensis 3.73 3.73 1 PMID:19888806 -2.3.3.9 * pinus densiflora 36.9 36.9 1 * -2.3.3.9 * pinus taeda 308.0 308.0 1 * -2.3.3.9 * pseudomonas aeruginosa 16.5 16.5 1 PMID:19549344 -2.3.3.9 * ricinus communis 2.5 2.5 1 PMID:16660272 -2.3.3.9 * streptomyces clavuligerus 0.0012 0.0012 1 PMID:11986926 -2.3.3.9 * streptomyces coelicolor 25090.0 12545.0131 2 PMID:11759686;PMID:11986926 -2.3.3.9 * zea mays 24.5 24.5 1 PMID:8286948 -2.4.1.1 * acetivibrio thermocellus 2.22 2.1500000000000004 2 * -2.4.1.1 * aquifex aeolicus 7.8 7.8 1 * -2.4.1.1 * badhamia polycephala 4.2 4.2 1 PMID:527584 -2.4.1.1 * clostridium pasteurianum 1.9 1.9 1 PMID:4157120 -2.4.1.1 * corynebacterium callunae 33.53 31.0 3 PMID:18576079;PMID:20113461;PMID:9307027 -2.4.1.1 * cuscuta reflexa 6.96 6.96 1 * -2.4.1.1 * dictyostelium discoideum 7.14 4.3 3 PMID:3110159 -2.4.1.1 * dioscorea cayenensis 400.0 300.0 3 * -2.4.1.1 * dioscorea cayenensis subsp. rotundata 0.36 0.36 1 * -2.4.1.1 * escherichia coli 0.118 0.118 1 PMID:4878695 -2.4.1.1 * klebsiella pneumoniae 17.7 17.7 1 PMID:12945 -2.4.1.1 * lathyrus oleraceus 11.7 5.8534999999999995 2 * -2.4.1.1 * lethenteron camtschaticum 75.0 67.5 2 PMID:20048 -2.4.1.1 * manduca sexta 12.12 10.08 3 * -2.4.1.1 * methanococcus maripaludis 0.0044 0.0044 1 PMID:8288525 -2.4.1.1 * musa x paradisiaca 1.5 1.5 1 PMID:7126533 -2.4.1.1 * neurospora crassa 65.0 65.0 1 PMID:156719 -2.4.1.1 * oryctolagus cuniculus 88.0 64.0 11 PMID:26082971;PMID:4633322 -2.4.1.1 * oryza sativa 1.8 1.8 1 * -2.4.1.1 * papiliotrema laurentii 1.76 1.76 1 PMID:27020 -2.4.1.1 * phymatotrichopsis omnivora 222.0 222.0 1 PMID:3579319 -2.4.1.1 * pyrococcus furiosus 52.0 41.5 2 PMID:19054743 -2.4.1.1 * rattus norvegicus 51.6 48.8 2 PMID:6421233 -2.4.1.1 * saccharolobus solfataricus 2.0 2.0 1 PMID:19682609 -2.4.1.1 * saccharomyces cerevisiae 85.0 44.9 4 PMID:1613787;PMID:6354094 -2.4.1.1 * solanum tuberosum 2.67 2.14 2 * -2.4.1.1 * spinacia oleracea 43.5 15.9 3 PMID:16661543;PMID:24309705 -2.4.1.1 * streptococcus salivarius 0.005 0.005 1 PMID:4689781 -2.4.1.1 * sus scrofa 70.0 50.0 2 PMID:4772683 -2.4.1.1 * thermus caldophilus 15.5 15.5 1 * -2.4.1.1 * triticum aestivum 57.2 57.2 1 PMID:15564531 -2.4.1.1 * typha latifolia 42.3 26.65 2 * -2.4.1.1 * xanthosoma sagittifolium 13.5 13.5 1 * -2.4.1.1 * zea mays 659.0 42.0 6 PMID:11361132;PMID:16665923;PMID:4730475 -2.4.1.10 * actinomyces naeslundii 3.747 1.3459999999999999 4 PMID:11500409 -2.4.1.10 * actinomyces viscosus 90.0 70.0 2 PMID:105761 -2.4.1.10 * aerobacter levanicum 470.0 470.0 1 PMID:5940635 -2.4.1.10 * aspergillus awamori 18511.0 10590.0 3 PMID:30031821 -2.4.1.10 * aureobasidium melanogenum 2100.0 1328.85 2 PMID:31686508 -2.4.1.10 * bacillus amyloliquefaciens 669.6 117.15 6 PMID:19916084;PMID:32365662 -2.4.1.10 * bacillus licheniformis 335.0 263.0 3 PMID:32439436 -2.4.1.10 * bacillus siamensis 15.95 15.95 1 PMID:36544824 -2.4.1.10 * bacillus subtilis 203.0 199.3 2 * -2.4.1.10 * bacillus velezensis 135.4 135.4 1 PMID:25524717 -2.4.1.10 * fructilactobacillus sanfranciscensis 206.0 206.0 1 PMID:15735966 -2.4.1.10 * gluconacetobacter diazotrophicus 2603.0 2582.0 2 PMID:10441728 -2.4.1.10 * klebsiella sp. l1 48.19 28.509999999999998 2 * -2.4.1.10 * leuconostoc mesenteroides 791.0 458.8 2 PMID:15652153;PMID:26487543 -2.4.1.10 * niallia circulans 593.0 304.91 2 * -2.4.1.10 * pseudomonas chlororaphis subsp. aurantiaca 173.0 172.0 2 PMID:18092457 -2.4.1.10 * pseudomonas savastanoi pv. phaseolicola 298.0 298.0 1 PMID:7751294 -2.4.1.10 * pseudomonas syringae pv. tomato 461.6 345.8 2 PMID:19337979;PMID:24955639 -2.4.1.10 * rahnella aquatilis 731.0 195.3 3 PMID:31230216 -2.4.1.10 * zymomonas mobilis 247.0 247.0 1 PMID:33571525 -2.4.1.100 * allium cepa 11.63 11.63 1 PMID:15720662 -2.4.1.100 * cichorium intybus 14.5 7.2555 2 PMID:19037899 -2.4.1.101 * bos taurus 0.106 0.0925 2 PMID:6445358 -2.4.1.101 * cricetulus griseus 8.4e-07 5.2e-07 2 PMID:7961837 -2.4.1.101 * homo sapiens 0.48 0.48 1 * -2.4.1.101 * oryctolagus cuniculus 19.8 11.155000000000001 2 PMID:2967294;PMID:6450208 -2.4.1.101 * rattus norvegicus 20.0 0.00065 3 PMID:6170335;PMID:8748150 -2.4.1.101 * sus scrofa 4.8 4.085 2 PMID:6452163;PMID:6457827 -2.4.1.101 * xenopus laevis 0.6 0.6 1 PMID:11555621 -2.4.1.102 * homo sapiens 0.00067 4e-05 9 PMID:10455130;PMID:1904002;PMID:1997166;PMID:2007580;PMID:9756922 -2.4.1.102 * mus musculus 9.2 9.2 1 PMID:12954635 -2.4.1.109 * candida albicans 1.2e-06 1.2e-06 1 PMID:8354289 -2.4.1.109 * saccharomyces cerevisiae 0.0035 0.00057 3 PMID:2001697;PMID:6989607;PMID:7864633 -2.4.1.11 * ascaris suum 4.3 4.3 1 PMID:3934170 -2.4.1.11 * bos taurus 63.0 21.0 6 PMID:2996630;PMID:3922242;PMID:4631036 -2.4.1.11 * homo sapiens 40.0 21.0 3 PMID:1731614;PMID:412671;PMID:8712 -2.4.1.11 * neurospora crassa 6.884 6.884 1 PMID:23841 -2.4.1.11 * oncorhynchus mykiss 26.0 26.0 1 PMID:4631637 -2.4.1.11 * oryctolagus cuniculus 25.0 11.3 5 PMID:4631037;PMID:6423631;PMID:814926;PMID:823021 -2.4.1.11 * phymatotrichopsis omnivora 1514.0 1514.0 1 * -2.4.1.11 * rattus norvegicus 40.0 22.0 3 PMID:1731614;PMID:4210703;PMID:6766448 -2.4.1.11 * saccharomyces cerevisiae 90.5 56.675 2 PMID:2116410;PMID:4365739 -2.4.1.11 * trichomonas vaginalis 2.5 2.5 1 PMID:28465215 -2.4.1.111 * picea abies 2.436 2.436 1 PMID:6210530 -2.4.1.111 * rosa sp. 0.036 0.036 1 PMID:10853 -2.4.1.115 * brassica oleracea 0.06 0.06 1 * -2.4.1.115 * silene dioica 0.0252 0.0252 1 PMID:751640 -2.4.1.115 * vitis vinifera 11.22 11.22 1 * -2.4.1.116 * silene dioica 0.00953 0.00953 1 PMID:751641 -2.4.1.118 * raphanus sativus 0.00046 0.00046 1 PMID:486500 -2.4.1.12 * gossypium hirsutum 0.0028 0.0028 1 PMID:12231765 -2.4.1.120 * brassica napus 0.018 0.018 1 PMID:11144274 -2.4.1.120 * raphanus sativus 0.0094 0.0094 1 * -2.4.1.121 * lathyrus oleraceus 2.976 0.6855 4 PMID:26057226 -2.4.1.121 * zea mays 4.029 2.4135 2 PMID:11537438;PMID:1719957 -2.4.1.122 * drosophila melanogaster 0.000168 0.000168 1 PMID:18824562 -2.4.1.122 * gallus gallus 0.00428 0.00428 1 PMID:3924026 -2.4.1.122 * homo sapiens 2.8e-06 2.8e-06 1 PMID:9582303 -2.4.1.122 * rattus norvegicus 3.43 0.01905 4 PMID:11673471;PMID:2125490 -2.4.1.122 * sus scrofa 0.81 0.01037 4 PMID:2125490;PMID:6801057 -2.4.1.123 * ajuga reptans 0.02826 0.02826 1 PMID:19880397 -2.4.1.123 * cucurbita pepo 32.1 32.1 1 PMID:7480343 -2.4.1.123 * dorcoceras hygrometricum 3.8 3.8 1 PMID:19760263 -2.4.1.123 * phaseolus vulgaris 8.75 8.75 1 PMID:7480343 -2.4.1.123 * spinacia oleracea 0.00114 0.00114 1 PMID:19880397 -2.4.1.125 * streptococcus mutans 89.7 22.35 4 PMID:2937877;PMID:6216919;PMID:6228638;PMID:6461359 -2.4.1.126 * solanum lycopersicum 0.00112 0.00112 1 * -2.4.1.128 * arabidopsis thaliana 1.356 0.6930000000000001 2 PMID:18295607 -2.4.1.128 * duboisia myoporoides 0.00084 0.00084 1 * -2.4.1.128 * nicotiana tabacum 0.114 0.0628 2 PMID:16662301 -2.4.1.13 * beta vulgaris 136.1 68.505 2 * -2.4.1.13 * cicer arietinum 9.5 8.15 2 * -2.4.1.13 * cucumis sativus 0.2083 0.0083 20 * -2.4.1.13 * denitrovibrio acetiphilus 7.61 7.61 1 PMID:40090494 -2.4.1.13 * glycine max 15.1 15.1 1 PMID:16664189 -2.4.1.13 * ipomoea batatas 3.27 3.27 1 * -2.4.1.13 * micractinium conductrix 9.39 9.39 1 PMID:37649634 -2.4.1.13 * oryza sativa 3.54 0.595 6 PMID:19401410 -2.4.1.13 * solanum tuberosum 6.9 2.8 5 * -2.4.1.13 * vicia faba 8.34 8.34 1 PMID:16653008 -2.4.1.13 * zea mays 180.0 8.0 6 PMID:16660299;PMID:16664445;PMID:6452264 -2.4.1.133 * homo sapiens 1.9 0.97 3 PMID:10640389;PMID:19032152 -2.4.1.133 * mus musculus 161000.0 4200.0 23 PMID:10409768 -2.4.1.134 * caenorhabditis elegans 2660.0 4.5 4 PMID:12584198 -2.4.1.134 * homo sapiens 84.0 6.0 5 PMID:11551958 -2.4.1.134 * mus musculus 84.0 6.0 5 PMID:11551958 -2.4.1.135 * homo sapiens 1.5 1.5 1 PMID:16300963 -2.4.1.136 * quercus rubra 0.0117 0.0117 1 * -2.4.1.137 * pyropia perforata 0.177 0.177 1 * -2.4.1.138 * kluyveromyces lactis 0.0056 0.0056 1 PMID:6211189 -2.4.1.14 * anabaena sp. 0.25 0.145 2 PMID:8942980 -2.4.1.14 * arabidopsis thaliana 2.19 0.875 4 PMID:24994761 -2.4.1.14 * cucumis sativus 0.03 0.015 13 * -2.4.1.14 * dunaliella tertiolecta 0.0025 0.0025 1 PMID:24414772 -2.4.1.14 * lathyrus oleraceus 4.22 4.22 1 * -2.4.1.14 * medicago sativa 0.0861 0.05445 4 PMID:19898977 -2.4.1.14 * neltuma juliflora 28.0 28.0 1 * -2.4.1.14 * oryza sativa 2.9 2.9 1 PMID:9620436 -2.4.1.14 * spinacia oleracea 79.5 68.25 2 PMID:2144103;PMID:7763376 -2.4.1.14 * triticum aestivum 1.1 0.8900000000000001 2 PMID:13769376;PMID:24407996 -2.4.1.14 * zea mays 25.0 25.0 1 PMID:16668210 -2.4.1.140 * leuconostoc citreum 34.7 34.7 1 PMID:29844508 -2.4.1.140 * streptococcus mutans 89.7 48.505 2 PMID:2533246;PMID:2937877 -2.4.1.143 * homo sapiens 20.0 20.0 1 PMID:7635144 -2.4.1.143 * rattus norvegicus 27.5 16.299999999999997 4 PMID:2952644;PMID:7841796 -2.4.1.143 * vigna radiata var. radiata 9.3 9.3 1 PMID:2960375 -2.4.1.144 * gallus gallus 8.3e-05 8.3e-05 1 PMID:6213618 -2.4.1.144 * homo sapiens 2.4e-05 2.5e-06 13 PMID:10699467;PMID:11768033;PMID:8137300;PMID:9762355 -2.4.1.144 * rattus norvegicus 5.52 0.01003 4 PMID:11011143;PMID:1325461 -2.4.1.145 * bos taurus 1.65 1.65 1 PMID:9278430 -2.4.1.146 * homo sapiens 3.2e-05 3.3e-06 5 PMID:1904002;PMID:1997166;PMID:8020479 -2.4.1.147 * homo sapiens 9e-05 9e-05 1 PMID:3160388 -2.4.1.147 * rattus norvegicus 0.00033 0.00033 1 PMID:3160388 -2.4.1.147 * sus scrofa 0.00034 0.00034 1 PMID:3160388 -2.4.1.148 * canis lupus familiaris 0.0003 0.0003 1 PMID:3160388 -2.4.1.148 * homo sapiens 0.00017 0.00017 1 PMID:3160388 -2.4.1.148 * mesocricetus auratus 0.00026 0.00021 2 PMID:15652185 -2.4.1.148 * ovis aries 0.00028 0.00028 1 PMID:3160388 -2.4.1.148 * platyrrhini 0.00016 0.00016 1 PMID:3160388 -2.4.1.148 * rattus norvegicus 0.0018 0.0011099999999999999 2 PMID:3160388 -2.4.1.148 * sus scrofa 0.00278 0.00278 1 PMID:3160388 -2.4.1.149 * bos taurus 0.118 0.118 1 PMID:8262950 -2.4.1.149 * rattus norvegicus 0.00153 0.00153 1 PMID:2970459 -2.4.1.15 * ascaris suum 150.5 150.5 2 PMID:22571853 -2.4.1.15 * cyberlindnera jadinii 2.03 1.063 2 PMID:21771638 -2.4.1.15 * dictyostelium discoideum 6.179 6.179 1 PMID:159657 -2.4.1.15 * halorhodospira halochloris 0.127 0.127 1 PMID:8480996 -2.4.1.15 * mycolicibacterium smegmatis 24.2 14.5 2 * -2.4.1.15 * neurospora crassa 31.48 31.48 1 * -2.4.1.15 * saccharomyces cerevisiae 15.0 0.74 9 PMID:17628825;PMID:18166160;PMID:1849964;PMID:19289151 -2.4.1.15 * saccharomyces pastorianus 0.3 0.3 1 PMID:13538966 -2.4.1.15 * selaginella lepidophylla 7.05 7.05 1 PMID:14684162 -2.4.1.15 * thermoplasma acidophilum 7.33 7.33 1 PMID:24508535 -2.4.1.15 * thermoproteus tenax 3.5 3.5 1 PMID:23626675 -2.4.1.15 * thermus thermophilus 149.6 100.85 4 PMID:15455210 -2.4.1.150 * rattus norvegicus 0.084 0.084 1 PMID:12626393 -2.4.1.150 * sus scrofa 0.058 0.058 1 PMID:9765297 -2.4.1.152 * homo sapiens 1.4 0.248 3 PMID:23263199;PMID:8323955;PMID:8748166 -2.4.1.152 * rattus norvegicus 0.002289 0.001153 2 PMID:16218937;PMID:8729003 -2.4.1.155 * homo sapiens 110.0 55.0695 2 PMID:10395745;PMID:8393437 -2.4.1.155 * mus musculus 0.0015 1.2e-06 7 PMID:10814701;PMID:18230362 -2.4.1.155 * rattus norvegicus 1.22 1.22 1 PMID:1531335 -2.4.1.158 * pseudohyphozyma bogoriensis 0.0242 0.0232 2 PMID:6213610 -2.4.1.16 * absidia glauca 0.0055 0.0055 1 PMID:8420947 -2.4.1.16 * amylomyces rouxii 0.01639 0.01639 1 PMID:16894 -2.4.1.16 * coprinopsis cinerea 4.7 2.45 2 * -2.4.1.16 * kluyveromyces bulgaricus 0.008 0.0028 3 * -2.4.1.16 * saccharomyces cerevisiae 42.7 42.7 1 PMID:2955198 -2.4.1.166 * cerastium arvense 0.000316 0.000283 2 PMID:24253101 -2.4.1.17 * canis lupus familiaris 8.2e-05 6e-05 11 PMID:12694866 -2.4.1.17 * homo sapiens 999.0 0.0044 63 PMID:12485962;PMID:12694866;PMID:15039073;PMID:15258112;PMID:15608137;PMID:15611481;PMID:17628876;PMID:18177842 -2.4.1.17 * oryctolagus cuniculus 0.682 0.35700000000000004 2 PMID:96815 -2.4.1.17 * rattus norvegicus 6.06 0.983 13 PMID:111930;PMID:1544492;PMID:3149280;PMID:6404284;PMID:6806274 -2.4.1.170 * glycine max 0.467 0.253 9 PMID:26019269 -2.4.1.172 * gardenia jasminoides 0.165 0.165 1 * -2.4.1.175 * bos taurus 0.0425 0.0425 1 PMID:10491092 -2.4.1.175 * escherichia coli 0.00334 0.002275 4 PMID:11943778 -2.4.1.175 * mus musculus 8e-06 7e-06 2 PMID:20729547 -2.4.1.177 * ipomoea batatas 70.1 70.1 1 PMID:6231280 -2.4.1.177 * vanilla planifolia 0.0279 0.0279 1 PMID:16667674 -2.4.1.178 * prunus serotina 0.018 0.0025 5 * -2.4.1.178 * triglochin maritima 0.94 0.625 2 PMID:6230992 -2.4.1.179 * homo sapiens 0.00077 0.00045 2 PMID:1429882;PMID:2495770 -2.4.1.179 * notamacropus eugenii 0.02 0.02 1 PMID:1901222 -2.4.1.18 * arabidopsis thaliana 0.107 0.107 2 PMID:17028209 -2.4.1.18 * bacillus licheniformis 80.88 65.15 6 PMID:36662316 -2.4.1.18 * bifidobacterium longum 18.5 18.5 1 PMID:32344341 -2.4.1.18 * cyanobacterium sp. 988.8 951.4 3 PMID:25731081 -2.4.1.18 * deinococcus geothermalis 7.2 7.2 1 PMID:19139240 -2.4.1.18 * deinococcus radiodurans 4.7 4.7 1 PMID:19139240 -2.4.1.18 * escherichia coli 460.0 379.5 2 PMID:407932 -2.4.1.18 * microvirga sp. mc18 791.21 605.55 8 PMID:33962003 -2.4.1.18 * mycobacterium tuberculosis 63.75 63.75 1 PMID:20444687 -2.4.1.18 * oryctolagus cuniculus 2850.0 1578.0 2 PMID:5288588;PMID:6447599 -2.4.1.18 * parageobacillus thermoglucosidasius 384.0 290.65 4 PMID:28082221;PMID:32044699;PMID:33166453 -2.4.1.18 * rhizomucor miehei 10.7 10.7 1 PMID:24767030 -2.4.1.18 * rhodothermus marinus 6003.6 4226.2 5 PMID:23041072;PMID:35219229;PMID:36461352 -2.4.1.18 * saccharomyces cerevisiae 0.2502 0.2502 1 * -2.4.1.18 * solanum tuberosum 1000000.0 500001.131 2 PMID:1258 -2.4.1.18 * thermomonospora curvata 90.28 90.28 1 * -2.4.1.180 * micrococcus luteus 8.7 7.35 2 PMID:21188072 -2.4.1.182 * escherichia coli 183.0 30.45 4 PMID:1495426;PMID:19883124;PMID:3049593;PMID:8982270 -2.4.1.185 * citrus x paradisi 0.0017 0.0017 1 PMID:2171434 -2.4.1.187 * bacillus subtilis 2.2e-06 2.2e-06 1 PMID:2977387 -2.4.1.189 * secale cereale 1.16 1.16 1 * -2.4.1.19 * alkalihalobacillus pseudalcaliphilus 6638.0 3365.15 2 PMID:21894524 -2.4.1.19 * anaerobranca gottschalkii 308.0 168.0 2 PMID:15340782;PMID:19367403 -2.4.1.19 * bacillus sp. (in: firmicutes) 877.9 205.0 5 PMID:19367403;PMID:22754298 -2.4.1.19 * bacillus sp. g-825-6 69.15 68.54 2 PMID:36524966 -2.4.1.19 * cytobacillus firmus 226.0 90.6 6 * -2.4.1.19 * evansella caseinilytica 33.7 33.7 1 PMID:34926120 -2.4.1.19 * evansella clarkii 9.72 9.72 1 PMID:33052686 -2.4.1.19 * geobacillus stearothermophilus 496.8 352.5 4 PMID:19367403;PMID:31758236;PMID:33741407;PMID:33837009 -2.4.1.19 * haloferax mediterranei 48.0 48.0 1 PMID:22134680 -2.4.1.19 * heyndrickxia coagulans 904.0 109.3 6 * -2.4.1.19 * klebsiella pneumoniae 0.5 0.5 1 PMID:19367403 -2.4.1.19 * lysinibacillus sphaericus 198.6 75.8 3 * -2.4.1.19 * niallia circulans 1650.0 224.4 8 PMID:1532314;PMID:16158259;PMID:19367403;PMID:33561459 -2.4.1.19 * paenibacillus campinasensis 347.9 347.9 1 PMID:18478375 -2.4.1.19 * paenibacillus illinoisensis 1200.0 1200.0 1 PMID:12728995 -2.4.1.19 * paenibacillus macerans 1027.0 14.4 13 PMID:19190904;PMID:19715296;PMID:5758537 -2.4.1.19 * paenibacillus pabuli 5000.0 4500.0 2 PMID:18704190 -2.4.1.19 * paenibacillus sp. 2268.0 89.7 3 PMID:17562284;PMID:20586059 -2.4.1.19 * priestia megaterium 60.39 60.39 1 PMID:18556815 -2.4.1.19 * salipaludibacillus agaradhaerens 66.3 66.3 1 PMID:22949876 -2.4.1.19 * shouchella lehensis 57.7 28.955000000000002 2 PMID:25362891 -2.4.1.19 * thermoanaerobacter sp. 127.0 79.63 2 PMID:18421598;PMID:19367403 -2.4.1.19 * thermoanaerobacterium thermosulfurigenes 255.0 255.0 1 PMID:19367403 -2.4.1.19 * thermococcus sp. 1400.0 711.5 2 PMID:10223990;PMID:19367403 -2.4.1.19 * unidentified microorganism 67.3 67.3 1 PMID:34122378 -2.4.1.190 * secale cereale 0.96 0.96 1 * -2.4.1.191 * secale cereale 0.14 0.14 1 * -2.4.1.194 * lithospermum erythrorhizon 2.94 0.002292 5 PMID:1832840 -2.4.1.195 * arabidopsis thaliana 0.561 0.561 1 * -2.4.1.195 * brassica napus 2.8 2.8 1 PMID:8373190 -2.4.1.195 * brassica oleracea 3.2 3.2 1 PMID:12232212 -2.4.1.195 * tropaeolum majus 45.0 45.0 1 * -2.4.1.197 * dictyostelium discoideum 1.33e-05 1.29e-05 3 PMID:2525124 -2.4.1.2 * gluconobacter oxydans 112.5 66.65 2 PMID:22961394 -2.4.1.20 * acetivibrio thermocellus 33.3 2.95 7 PMID:37833899;PMID:5653182 -2.4.1.20 * caldicellulosiruptor bescii 3.58 1.3849999999999998 6 PMID:35273293 -2.4.1.20 * cellulomonas gilvus 40.8 34.099999999999994 2 PMID:6223623 -2.4.1.20 * cellulomonas uda 14.4 7.78 3 PMID:19487233;PMID:22591555 -2.4.1.20 * thermoclostridium stercorarium 4.7 4.7 1 PMID:9249035 -2.4.1.20 * thermosipho africanus 58.61 0.365 12 PMID:28687766 -2.4.1.20 * thermotoga maritima 2.66 2.66 1 PMID:12596851 -2.4.1.20 * thermotoga neapolitana 11.8 11.8 1 PMID:10960102 -2.4.1.20 * unidentified 0.61 0.61 1 * -2.4.1.201 * gallus gallus 0.032 0.016000225 2 PMID:10962001 -2.4.1.202 * zea mays 24.0 2.6 9 PMID:11851909;PMID:16666853 -2.4.1.203 * phaseolus lunatus 0.57 0.28509999999999996 2 PMID:16666929 -2.4.1.203 * phaseolus vulgaris 6.6e-06 6.6e-06 1 * -2.4.1.205 * helix pomatia 3.466 3.466 1 PMID:2505854 -2.4.1.206 * homo sapiens 0.00254 0.00123 7 PMID:11384981;PMID:2960671 -2.4.1.206 * mus musculus 0.00254 0.00174 5 PMID:11384981 -2.4.1.206 * rattus norvegicus 4.2e-07 1.25e-07 4 PMID:8910533 -2.4.1.206 * xenopus sp. 6.5e-07 6.5e-07 1 PMID:10561117 -2.4.1.207 * arabidopsis thaliana 173.125 20.0 24 PMID:33825243 -2.4.1.207 * brachypodium distachyon 2361.25 315.0 26 PMID:33825243 -2.4.1.207 * brassica oleracea var. botrytis 0.812 0.812 1 PMID:12826015 -2.4.1.207 * fragaria chiloensis 0.255 0.255 1 PMID:32403246 -2.4.1.207 * hordeum vulgare 60.51 0.072 8 PMID:17329246;PMID:19076217 -2.4.1.207 * populus tremula x populus tremuloides 0.18 0.18 1 PMID:15804235 -2.4.1.207 * populus trichocarpa 54758.8 1339.065 28 PMID:33825243 -2.4.1.207 * triticum aestivum 10453.8 697.5 27 PMID:33825243 -2.4.1.207 * vigna radiata var. radiata 0.216 0.216 1 * -2.4.1.208 * acholeplasma laidlawii 8.05 8.05 1 PMID:10220338 -2.4.1.209 * sphagnum fallax 1.054 1.054 1 * -2.4.1.21 * arthrobacter sp. 0.93 0.93 1 PMID:14304835 -2.4.1.21 * escherichia coli 505.0 499.5 2 PMID:2288 -2.4.1.21 * lathyrus oleraceus 15.87 15.87 1 PMID:24186793 -2.4.1.21 * oryza sativa 0.039 0.036000000000000004 2 * -2.4.1.21 * solanum tuberosum 0.026 0.026 1 * -2.4.1.21 * spinacia oleracea 3.0 0.28 7 PMID:4208773;PMID:5073245 -2.4.1.21 * zea mays 12.2 6.16 7 PMID:26940263;PMID:6449907;PMID:9578601 -2.4.1.21 * zea mays subsp. mays 65.47 65.47 1 PMID:14298833 -2.4.1.210 * citrus maxima 0.013 0.013 1 * -2.4.1.210 * citrus sinensis 0.018 0.018 1 * -2.4.1.211 * bifidobacterium bifidum 10.0 10.0 1 PMID:15933016 -2.4.1.211 * bifidobacterium bifidum jcm 1254 10.0 4.36 26 PMID:17587697;PMID:17690443 -2.4.1.211 * bifidobacterium longum 19.0 19.0 1 PMID:15933016 -2.4.1.212 * homo sapiens 6.27e-08 2.315e-08 48 PMID:17493932 -2.4.1.212 * pasteurella multocida 0.05 0.05 1 * -2.4.1.212 * streptococcus dysgalactiae subsp. equisimilis 37.0 37.0 1 PMID:22745284 -2.4.1.214 * homo sapiens 1.6 1.6 1 PMID:11555615 -2.4.1.214 * vigna radiata 43.35 21.7105 2 PMID:10419500;PMID:8748155 -2.4.1.216 * enterococcus faecium 0.82 0.82 1 PMID:11972617 -2.4.1.216 * lactococcus lactis 32.4 32.4 1 PMID:11553642 -2.4.1.216 * leuconostoc weissella 0.8 0.8 1 PMID:11972617 -2.4.1.217 * rhodothermus marinus 156.0 156.0 1 PMID:14701859 -2.4.1.217 * rubrobacter xylanophilus 0.0232 0.0232 1 PMID:21166895 -2.4.1.217 * thermus thermophilus hb27 45.0 5.3 3 PMID:20356840 -2.4.1.218 * rauvolfia serpentina 12.17 6.81 2 PMID:12542702 -2.4.1.22 * aggregatibacter actinomycetemcomitans 3.3 3.3 1 PMID:34670186 -2.4.1.221 * cricetulus griseus 0.784 0.784 1 PMID:9525914 -2.4.1.225 * oncorhynchus mykiss 1.2e-05 1.2e-05 1 PMID:10864928 -2.4.1.226 * homo sapiens 4e-08 4e-08 1 PMID:12716890 -2.4.1.226 * mus musculus 2.4e-06 1.5e-06 2 PMID:20729547 -2.4.1.227 * escherichia coli 0.37 6.4e-06 5 PMID:10790316;PMID:1649817;PMID:17692452 -2.4.1.228 * homo sapiens 1e-07 1e-07 1 PMID:10748143 -2.4.1.228 * oryctolagus cuniculus 0.000256 0.0001205 4 PMID:7943326 -2.4.1.228 * rattus norvegicus 0.00458 0.00458 1 PMID:3921539 -2.4.1.229 * dictyostelium sp. 0.00023 0.00023 1 PMID:10593934 -2.4.1.230 * caldicellulosiruptor saccharolyticus 191.3 111.2 2 PMID:21670511 -2.4.1.230 * pyrococcus sp. 10.7 10.7 1 PMID:24391053 -2.4.1.231 * agaricus bisporus 4.35 4.35 1 PMID:9813313 -2.4.1.231 * grifola frondosa 4.2 4.2 1 PMID:9797287 -2.4.1.231 * lentinus sajor-caju 13.9 13.9 1 PMID:12880768 -2.4.1.231 * schizophyllum commune 9.85 9.825 2 PMID:10393097;PMID:9872418 -2.4.1.234 * vigna mungo 0.335 0.335 1 * -2.4.1.236 * citrus maxima 0.000624 0.000624 1 PMID:1939145 -2.4.1.237 * euonymus alatus 1.76 1.76 1 * -2.4.1.237 * paederia scandens 1.63 1.63 1 * -2.4.1.237 * vitis labrusca 0.00015 0.00015 1 PMID:21755362 -2.4.1.242 * gracilaria tenuistipitata 0.229 0.229 1 PMID:10467041 -2.4.1.242 * lathyrus oleraceus 10.0 10.0 1 PMID:12232029 -2.4.1.242 * triticum aestivum 0.00032 0.00017500000000000003 2 PMID:9765530 -2.4.1.243 * allium cepa 26.54 26.54 1 PMID:15720662 -2.4.1.243 * asparagus officinalis 136.8 136.8 1 * -2.4.1.247 * opitutus terrae 29.0 1.01 8 * -2.4.1.248 * agreia sp. d1110 8.1 8.1 1 PMID:33624786 -2.4.1.248 * microbacterium trichothecenolyticum 3.55 3.55 1 PMID:33624786 -2.4.1.248 * niallia circulans 14.6 14.2 3 PMID:22075636 -2.4.1.249 * clitoria ternatea 2.29 0.006 6 PMID:17668234 -2.4.1.25 * aquifex aeolicus 44.2 44.2 2 PMID:35209232 -2.4.1.25 * arabidopsis thaliana 4.87 3.0 2 PMID:16665877 -2.4.1.25 * corynebacterium glutamicum 21.8 21.8 2 PMID:22865069;PMID:35209232 -2.4.1.25 * escherichia coli 9400.0 4715.0 2 PMID:35209232;PMID:791642 -2.4.1.25 * pyrobaculum aerophilum 450.0 450.0 1 PMID:35209232 -2.4.1.25 * pyrobaculum calidifontis 690.0 690.0 2 PMID:32950528;PMID:35209232 -2.4.1.25 * saccharomyces cerevisiae 4.91 4.38 2 PMID:10873545;PMID:1597178 -2.4.1.25 * solanum tuberosum 47.5 47.5 1 PMID:35209232 -2.4.1.25 * streptococcus agalactiae 54.0 54.0 1 PMID:35209232 -2.4.1.25 * sus scrofa 1.36 1.36 1 PMID:16798776 -2.4.1.25 * synechocystis sp. 5.84 5.84 1 PMID:19576307 -2.4.1.25 * synechocystis sp. pcc 6803 5.84 5.84 1 PMID:35209232 -2.4.1.25 * thermococcus litoralis 25.7 15.45 2 PMID:10348846;PMID:9310375 -2.4.1.25 * thermus aquaticus 2.9 2.9 2 PMID:10049841;PMID:35209232 -2.4.1.25 * thermus brockianus 17734.0 17734.0 1 PMID:35209232 -2.4.1.25 * thermus filiformis 159.0 159.0 1 PMID:35209232 -2.4.1.25 * thermus sp. 120.0 120.0 1 PMID:39827568 -2.4.1.25 * thermus thermophilus 400.0 202.595 2 PMID:17420245;PMID:35209232 -2.4.1.253 * scutellaria baicalensis 13.5 13.5 1 PMID:10724177 -2.4.1.254 * bellis perennis 0.0288 0.0288 1 PMID:15509561 -2.4.1.255 * homo sapiens 0.161 0.161 1 PMID:16231908 -2.4.1.255 * rattus norvegicus 0.00111 0.00111 1 PMID:1533623 -2.4.1.262 * glycine max 7.0 3.671 2 PMID:12172845 -2.4.1.266 * methanococcoides burtonii 0.0116 0.0116 1 PMID:16428406 -2.4.1.266 * persephonella marina 94.0 25.5 4 PMID:17189358 -2.4.1.266 * rhodopirellula baltica 1.1 0.17 3 PMID:23921581 -2.4.1.266 * rubrobacter xylanophilus dsm 9941 0.0629 0.0629 1 PMID:21166895 -2.4.1.268 * persephonella marina 284.3 47.0 3 PMID:17369297 -2.4.1.269 * rhodothermus marinus 70.0 70.0 1 PMID:10585410 -2.4.1.270 * rhodopirellula baltica 3.1 1.72 3 PMID:23921581 -2.4.1.271 * crocus sativus 10.8 7.2 2 * -2.4.1.274 * homo sapiens 0.0613 0.0613 1 PMID:10320813 -2.4.1.275 * mus musculus 1.344 1.344 1 PMID:8781973 -2.4.1.279 * lachnoclostridium phytofermentans 54.0 8.1 7 PMID:21808968 -2.4.1.28 * enterobacteria phage t6 0.0067 0.0042 2 PMID:13753193 -2.4.1.281 * bacteroides fragilis 28.5 28.5 1 PMID:21539815 -2.4.1.288 * mycobacterium tuberculosis 1.6 0.012 13 PMID:22499274 -2.4.1.296 * petunia x hybrida 0.05 0.05 1 PMID:24258583 -2.4.1.298 * dahlia pinnata 0.18 0.18 1 * -2.4.1.30 * euglena gracilis 0.5 0.4 2 PMID:6066291 -2.4.1.305 * escherichia coli 0.025 0.013600000000000001 2 PMID:18487334 -2.4.1.31 * euglena gracilis 24.0 24.0 1 PMID:5901055 -2.4.1.314 * panax notoginseng 0.044 0.02215 2 * -2.4.1.319 * ruminococcus albus 2.03 2.03 1 PMID:23093406 -2.4.1.32 * lathyrus oleraceus 0.0017 0.0017 1 PMID:7685647 -2.4.1.320 * bacteroides thetaiotaomicron 258.0 144.0 2 PMID:23943617 -2.4.1.321 * saccharophagus degradans 62.0 62.0 1 PMID:26041776 -2.4.1.329 * ilumatobacter coccineus 45.0 45.0 1 PMID:31405215 -2.4.1.337 * acholeplasma laidlawii 12.0 12.0 1 PMID:8995384 -2.4.1.34 * aspergillus fumigatus 0.0109 0.0096 3 PMID:8067773 -2.4.1.34 * aspergillus nidulans 0.85 0.85 1 PMID:8755864 -2.4.1.34 * candida albicans 0.0125 0.0041 3 PMID:9727393 -2.4.1.34 * lathyrus oleraceus 27.9 27.9 1 PMID:8143748 -2.4.1.34 * neurospora crassa 14.0 0.0987 4 PMID:7614368;PMID:7947947 -2.4.1.34 * phaseolus vulgaris 1440.0 1440.0 1 PMID:9362565 -2.4.1.34 * saccharomyces cerevisiae 4.0 0.41346 4 PMID:11337502;PMID:36949198;PMID:7649185 -2.4.1.344 * sus scrofa 11410.0 11410.0 1 PMID:7592879 -2.4.1.345 * mycobacterium tuberculosis 9.4 9.4 1 PMID:15939292 -2.4.1.35 * agrotis ipsilon 0.0241 0.0131 9 * -2.4.1.35 * bombyx mori 9e-05 9e-06 13 PMID:11846783 -2.4.1.35 * manduca sexta 0.0198 0.004 15 * -2.4.1.35 * melanoplus sanguinipes 0.0315 0.0132 13 * -2.4.1.35 * nicotiana tabacum 1.19 0.354 5 PMID:11454003 -2.4.1.35 * periplaneta americana 0.0034 0.0011 9 * -2.4.1.35 * tenebrio molitor 0.0028 0.0009499999999999999 6 * -2.4.1.35 * tribolium confusum 0.0032 0.00155 8 * -2.4.1.359 * marinobacter adhaerens 45.2 25.0 6 PMID:29470619 -2.4.1.359 * marinobacter salinexigens 1.17 0.7649999999999999 2 PMID:38363425 -2.4.1.362 * apilactobacillus kunkeei 34.3 34.3 1 * -2.4.1.37 * dictyostelium discoideum 72.0 72.0 1 PMID:15123660 -2.4.1.37 * homo sapiens 3.3 1.6400000000000001 4 PMID:18405657;PMID:8529660;PMID:901499 -2.4.1.373 * leuconostoc citreum 12.0 12.0 1 PMID:25756290 -2.4.1.38 * bos taurus 10.7 10.7 1 PMID:35107 -2.4.1.38 * helicobacter pylori 160.0 160.0 1 PMID:18491328 -2.4.1.38 * homo sapiens 8.4 5.800000000000001 4 PMID:414742;PMID:8444150;PMID:8706738 -2.4.1.38 * rattus norvegicus 19.8 0.1805 4 PMID:3089277;PMID:3105591;PMID:627561;PMID:8375379 -2.4.1.38 * sus scrofa 0.035 0.035 1 PMID:990260 -2.4.1.387 * bacillus sp. nrrl b-21195 2.25 2.25 1 PMID:14553982 -2.4.1.387 * sporosarcina globispora 22.9 11.46 4 PMID:12400677;PMID:16233396 -2.4.1.394 * azotobacter chroococcum 6.6 6.6 1 PMID:26868718 -2.4.1.394 * exiguobacterium artemiae 2.2 2.2 1 PMID:26590275 -2.4.1.394 * paenibacillus beijingensis 6.3 6.3 1 PMID:28399167 -2.4.1.4 * bifidobacterium thermophilum 1.4 1.4 1 PMID:39476901 -2.4.1.4 * cellulomonas carbonis 4200.0 2650.0 2 PMID:28240031 -2.4.1.4 * deinococcus geothermalis 44.0 7.03 4 PMID:18522649;PMID:39631600 -2.4.1.4 * neisseria perflava 3.71 3.71 1 PMID:4809624 -2.4.1.4 * neisseria polysaccharea 9.57 9.57 1 * -2.4.1.4 * salinispirillum sp. lh10-3-1 108.2 108.2 1 PMID:36795143 -2.4.1.40 * homo sapiens 7.0 5.7 3 PMID:2104827;PMID:2121135 -2.4.1.40 * sus scrofa 30.0 30.0 1 PMID:14962 -2.4.1.41 * bos taurus 30.6 2.0100000000000002 4 PMID:3082881;PMID:7606161;PMID:8910012 -2.4.1.41 * homo sapiens 321.0 62.5 14 PMID:17215257;PMID:7592619;PMID:9295285;PMID:9587664 -2.4.1.41 * mus musculus 0.15 0.15 1 PMID:3082881 -2.4.1.41 * ovis sp. 0.11 0.11 1 PMID:7592620 -2.4.1.41 * rattus norvegicus 2.12 1.2550000000000001 2 PMID:6809738 -2.4.1.41 * sus scrofa 2.12 1.865 4 PMID:15646032;PMID:1618775;PMID:7592620;PMID:9746219 -2.4.1.43 * arabidopsis thaliana 0.00095 0.00095 1 PMID:14499571 -2.4.1.43 * vigna angularis 0.0013 0.0013 1 PMID:11515534 -2.4.1.44 * salmonella enterica subsp. enterica serovar typhimurium 0.00284 0.0015 3 PMID:4553445;PMID:4898284 -2.4.1.46 * chlorobaculum tepidum 7.04 3.54655 2 PMID:21764989 -2.4.1.46 * spinacia oleracea 2.2 2.2 1 PMID:24194148 -2.4.1.47 * rattus norvegicus 0.002733 0.002094 2 PMID:1260034;PMID:6792465 -2.4.1.49 * acetivibrio thermocellus 64.2 8.7 5 PMID:14499574;PMID:20678539;PMID:5773308 -2.4.1.49 * thermoclostridium stercorarium 16.0 11.1 8 PMID:21344678;PMID:9249035 -2.4.1.5 * acetobacter tropicalis 6062.0 5946.0 2 * -2.4.1.5 * leuconostoc citreum 686.0 686.0 1 PMID:19734722 -2.4.1.5 * leuconostoc lactis 393.0 204.0 4 PMID:19853426 -2.4.1.5 * leuconostoc mesenteroides 335.1 38.7 20 PMID:15723174;PMID:17673948;PMID:17892930;PMID:18207273;PMID:18418751;PMID:18600046;PMID:22815573;PMID:23020182;PMID:23044124;PMID:238637;PMID:29101023;PMID:2938733;PMID:6156708 -2.4.1.5 * pediococcus pentosaceus 46.0 27.0 4 PMID:25434098 -2.4.1.5 * streptococcus mutans 4.47 3.5 3 PMID:33748439 -2.4.1.5 * weissella cibaria 1.0 1.0 1 PMID:23464916 -2.4.1.5 * weissella confusa 18.9 9.05 4 PMID:24299811;PMID:25603169;PMID:26861959 -2.4.1.50 * gallus gallus 0.0147 0.007814999999999999 2 PMID:6210830;PMID:938472;PMID:986940 -2.4.1.56 * neisseria meningitidis 0.08 0.08 1 PMID:10521543 -2.4.1.62 * campylobacter jejuni 16.0 16.0 1 PMID:32146932 -2.4.1.62 * gallus gallus 0.463 0.463 1 PMID:8748162 -2.4.1.62 * mus musculus 9e-08 6.05e-08 4 PMID:10502288;PMID:10905635 -2.4.1.63 * linum usitatissimum 0.0238 0.0238 1 PMID:5417265 -2.4.1.64 * euglena gracilis 1.63 0.9219999999999999 2 PMID:4623846 -2.4.1.64 * kocuria varians 18.2 18.2 1 * -2.4.1.65 * helicobacter pylori 0.0238 0.02005 2 PMID:12676935 -2.4.1.65 * homo sapiens 567.0 2.05 5 PMID:11171070;PMID:11425796;PMID:7287719 -2.4.1.65 * silene latifolia subsp. alba 0.000312 2.6e-05 15 PMID:15864437 -2.4.1.66 * gallus gallus 0.57 0.0555 6 PMID:556672;PMID:6210830;PMID:743222;PMID:817743;PMID:942695;PMID:986940 -2.4.1.66 * homo sapiens 0.33 0.05365 4 PMID:12475640;PMID:19064;PMID:7350920 -2.4.1.67 * arabidopsis thaliana 0.28 0.28 1 PMID:26483807 -2.4.1.67 * cucumis melo 0.000833 0.00047149999999999997 2 PMID:24232761 -2.4.1.67 * cucumis sativus 0.04167 0.0075 22 * -2.4.1.67 * cucurbita pepo 0.0185 0.0185 1 * -2.4.1.67 * lathyrus oleraceus 0.5 0.5 1 PMID:11675396 -2.4.1.67 * lens culinaris 0.55 0.55 1 PMID:10334866 -2.4.1.67 * vigna angularis 1.3 0.05 5 PMID:10652123;PMID:9576785 -2.4.1.68 * bombyx mori 3.5e-05 3.5e-05 1 PMID:8130393 -2.4.1.68 * cricetulus griseus 0.784 0.784 1 PMID:9525914 -2.4.1.68 * homo sapiens 0.497 0.417 5 PMID:16344263;PMID:9133635;PMID:9870354 -2.4.1.68 * mamestra brassicae 0.000187 0.000187 1 PMID:8130393 -2.4.1.68 * rattus norvegicus 1.22e-05 7.6e-07 11 PMID:8889825;PMID:8910378 -2.4.1.68 * spodoptera frugiperda 8.3e-05 7.3e-05 2 PMID:8130393 -2.4.1.68 * sus scrofa 4.37 2.1850195 2 PMID:8910378 -2.4.1.69 * escherichia coli 0.873 0.8625 4 PMID:18842005 -2.4.1.69 * helicobacter pylori 0.7 0.7 1 PMID:38218286 -2.4.1.69 * homo sapiens 188.0 95.75 2 PMID:1733969;PMID:8690714 -2.4.1.69 * sus scrofa 129.0 65.0705 2 PMID:6246105;PMID:7592879 -2.4.1.7 * bifidobacterium adolescentis 213.0 161.0 2 PMID:14740189;PMID:21900303 -2.4.1.7 * bifidobacterium longum 122.1 122.1 1 PMID:29380264 -2.4.1.7 * leuconostoc mesenteroides 285.0 174.25 10 PMID:1368718;PMID:17215056;PMID:18038113;PMID:32924353;PMID:9063981 -2.4.1.7 * thermobacillus sp. zcth02-b1 6.42 6.42 1 PMID:31470069 -2.4.1.71 * glycine max 0.000912 0.000912 1 * -2.4.1.74 * dictyostelium discoideum 2.3e-07 2.3e-07 1 PMID:15558817 -2.4.1.74 * rattus norvegicus 0.0076 0.0076 1 PMID:115498 -2.4.1.79 * canis lupus familiaris 0.000565 0.000565 1 PMID:6425294 -2.4.1.8 * bacillus subtilis 7.0 7.0 1 PMID:37850132 -2.4.1.8 * lactobacillus acidophilus 52.0 52.0 1 PMID:19919544 -2.4.1.8 * levilactobacillus brevis 18.0 16.45 2 PMID:2143366 -2.4.1.8 * paenibacillus sp. 50.0 50.0 1 * -2.4.1.80 * cricetulus griseus 1.39e-06 1.39e-06 1 PMID:12139966 -2.4.1.80 * homo sapiens 0.00036 0.00024 5 PMID:15141021 -2.4.1.80 * mus musculus 8.2e-06 8.2e-06 1 PMID:9507988 -2.4.1.80 * raphanus sativus 0.0002 0.0002 1 PMID:8534980 -2.4.1.80 * rattus norvegicus 0.0436 0.021955 2 PMID:1533793;PMID:8567691 -2.4.1.80 * sus scrofa 0.0007 0.00035325 2 PMID:3156635 -2.4.1.81 * petroselinum crispum 0.401 0.401 1 PMID:5058406 -2.4.1.82 * ajuga reptans 0.00138 0.00138 1 PMID:19880397 -2.4.1.82 * arabidopsis thaliana 0.00258 0.00258 1 PMID:19880397 -2.4.1.82 * glycine max 0.045 0.045 1 * -2.4.1.82 * lathyrus oleraceus 5e-05 5e-05 1 PMID:12244450 -2.4.1.82 * oryza sativa 0.56 0.2 3 * -2.4.1.82 * phaseolus vulgaris 0.045 0.045 1 * -2.4.1.82 * spinacia oleracea 0.00396 0.00396 1 PMID:19880397 -2.4.1.82 * vicia faba 0.497 0.2491 2 PMID:4774118 -2.4.1.83 * gallus gallus 0.000285 0.000285 1 PMID:2917659 -2.4.1.83 * mus musculus 0.0016 0.0016 1 PMID:1606967 -2.4.1.83 * rattus norvegicus 0.07 0.07 1 PMID:4065149 -2.4.1.83 * saccharomyces cerevisiae 0.475 0.25015 2 PMID:2659345;PMID:6989607 -2.4.1.85 * sorghum bicolor 0.76 0.76 1 PMID:4416442 -2.4.1.86 * mus musculus 1.344 1.344 1 PMID:8781973 -2.4.1.87 * bos taurus 4.3 2.7 2 PMID:19245254;PMID:3932335 -2.4.1.87 * mus musculus 265.0 132.5005 2 PMID:3084477 -2.4.1.88 * canis lupus familiaris 5.9e-05 5.9e-05 1 PMID:6809754 -2.4.1.9 * aureobasidium pullulans 459.0 459.0 1 PMID:18394739 -2.4.1.9 * halomicrobium sp. ibsba 56.5 56.5 1 PMID:33918392 -2.4.1.9 * lactobacillus gasseri 10.5 10.5 1 PMID:23645191 -2.4.1.9 * lactobacillus johnsonii 719.0 276.0 6 PMID:18408060 -2.4.1.9 * lactobacillus mulieris 480.0 480.0 1 PMID:39090787 -2.4.1.9 * limosilactobacillus reuteri 180.0 103.7 3 PMID:12200292;PMID:14988011;PMID:15710400 -2.4.1.9 * neobacillus drentensis 38.4 36.25 2 PMID:37491698 -2.4.1.90 * bos taurus 10.7 5.350002675 2 PMID:15449940;PMID:35107 -2.4.1.90 * homo sapiens 8.4 0.00044 19 PMID:15835923;PMID:414742;PMID:8444150;PMID:8706738 -2.4.1.90 * rattus norvegicus 19.8 0.1805 4 PMID:3089277;PMID:3105591;PMID:627561;PMID:8375379 -2.4.1.90 * sus scrofa 0.035 0.035 1 PMID:990260 -2.4.1.91 * triticum aestivum 0.00143 0.001073 2 PMID:12943758 -2.4.1.92 * mus musculus 4566.0 53.3 3 PMID:14579597;PMID:8245020 -2.4.1.92 * rattus norvegicus 0.0004 0.0002745 2 PMID:3109491;PMID:6118272 -2.4.1.96 * poterioochromonas malhamensis 198.0 198.0 1 * -2.4.1.96 * pyropia haitanensis 0.0038 0.0038 1 PMID:31324146 -2.4.1.97 * ochromonas danica 26.5 26.5 1 PMID:24018693 -2.4.1.97 * poterioochromonas malhamensis 10.92 10.92 1 * -2.4.1.99 * agave tequilana 231.0 231.0 1 * -2.4.1.99 * asparagus officinalis 2.97 2.97 1 * -2.4.1.99 * aspergillus aculeatus 2635.0 2635.0 1 PMID:17056145 -2.4.1.99 * cichorium intybus 0.054 0.054 1 PMID:19037899 -2.4.1.99 * helianthus tuberosus 0.126 0.126 1 * -2.4.1.99 * lolium arundinaceum 550.12 550.12 1 PMID:38904715 -2.4.1.99 * rhodotorula sp. 75.4 37.95 2 PMID:18481059 -2.4.2.1 * bacillus subtilis 100.0 86.5 2 PMID:99174 -2.4.2.1 * bos taurus 78.3 41.025 4 PMID:1445943;PMID:18585465;PMID:7211;PMID:9972 -2.4.2.1 * cricetulus griseus 60.0 60.0 1 PMID:825137;PMID:99640 -2.4.2.1 * enterobacter cloacae 7.9 7.9 1 * -2.4.2.1 * escherichia coli 195.0 8.83 13 PMID:11437593;PMID:16247956;PMID:21672603;PMID:235429;PMID:3042752 -2.4.2.1 * exiguobacterium acetylicum 195.1 195.1 1 PMID:1368697 -2.4.2.1 * geobacillus stearothermophilus 405.0 91.6 3 PMID:8782414 -2.4.2.1 * grouper iridovirus 3.47 1.17 5 PMID:20124695 -2.4.2.1 * halalkalibacterium halodurans 30.23 30.23 1 PMID:20063024 -2.4.2.1 * halobacterium salinarum 2890.0 370.0 3 PMID:9457844 -2.4.2.1 * haloferax volcanii 5420.0 3740.0 3 PMID:9457844 -2.4.2.1 * helicobacter pylori 80.4 9.8 7 PMID:28336275;PMID:29430816 -2.4.2.1 * homo sapiens 139.0 50.15 10 PMID:114517;PMID:18938130;PMID:412851;PMID:6771283;PMID:99639 -2.4.2.1 * oryctolagus cuniculus 50.0 47.12 3 PMID:1390;PMID:31138;PMID:414743;PMID:99638 -2.4.2.1 * pectobacterium carotovorum 48.5 48.5 1 PMID:1368721 -2.4.2.1 * plasmodium falciparum 0.023 0.0195 2 PMID:18957439 -2.4.2.1 * plasmodium lophurae 8.7 8.7 1 PMID:3920217 -2.4.2.1 * pyrococcus furiosus 0.0179 0.0179 2 PMID:17419725 -2.4.2.1 * rattus norvegicus 143.0 137.5 2 PMID:37803;PMID:99637 -2.4.2.1 * salmonella enterica subsp. enterica serovar typhimurium 301.0 230.5 2 PMID:235429;PMID:4570469;PMID:99637 -2.4.2.1 * schistosoma mansoni 0.034 0.017410000000000002 2 PMID:24794680 -2.4.2.10 * corynebacterium ammoniagenes 423.0 148.0 4 PMID:17921291 -2.4.2.10 * escherichia coli 27.0 21.1 2 PMID:2419315;PMID:9222315 -2.4.2.10 * homo sapiens 0.000172 4.05e-05 4 PMID:17237621 -2.4.2.10 * mus musculus 0.69 0.40249999999999997 2 PMID:6893554;PMID:692383 -2.4.2.10 * mycobacterium tuberculosis 105.0 17.0 3 PMID:22075667;PMID:28446777 -2.4.2.10 * plasmodium falciparum 4.32 2.4493150000000004 2 PMID:15147974 -2.4.2.10 * rhizobium leguminosarum 61.0 61.0 1 PMID:9305779 -2.4.2.10 * saccharomyces cerevisiae 81.6 42.5 6 PMID:18020427;PMID:218950;PMID:224912;PMID:357907;PMID:358857 -2.4.2.10 * salmonella enterica subsp. enterica serovar typhimurium 95.7 95.7 1 PMID:2271660 -2.4.2.10 * thermus thermophilus 300.0 300.0 1 PMID:8720144 -2.4.2.12 * homo sapiens 0.0741 0.0395 8 PMID:21826208 -2.4.2.12 * rattus norvegicus 0.003 0.0016125 2 PMID:4344987;PMID:4402158 -2.4.2.14 * bacillus subtilis 0.043 0.043 1 PMID:6443594 -2.4.2.14 * eremothecium gossypii 3.0 3.0 1 PMID:16204483 -2.4.2.14 * escherichia coli 17.2 17.2 1 PMID:372191;PMID:6443594 -2.4.2.14 * glycine max 15.6 15.6 1 PMID:6538402 -2.4.2.14 * homo sapiens 0.0055 0.00211 4 PMID:4348201;PMID:4348202;PMID:649615 -2.4.2.14 * rattus norvegicus 1.82 1.82 1 PMID:447621 -2.4.2.14 * schizosaccharomyces pombe 0.02 0.02 1 PMID:4371850 -2.4.2.15 * oryctolagus cuniculus 4.87 4.87 1 PMID:14008731 -2.4.2.16 * canis lupus familiaris 4.6 4.6 1 PMID:14085385 -2.4.2.17 * corynebacterium glutamicum 2.19 2.19 1 PMID:22172596 -2.4.2.18 * corynebacterium glutamicum 0.049 0.049 1 PMID:8534114 -2.4.2.18 * klebsiella aerogenes 734.0 734.0 1 PMID:4352716 -2.4.2.18 * neurospora crassa 16.0 16.0 1 PMID:5842052 -2.4.2.18 * ogataea henricii 0.4 0.4 1 PMID:32668 -2.4.2.18 * pectobacterium carotovorum 24.5 24.5 1 PMID:338606 -2.4.2.18 * saccharomyces cerevisiae 1.58 1.58 1 PMID:2651124 -2.4.2.18 * salmonella enterica subsp. enterica serovar typhimurium 1540.0 2.95 6 PMID:4350997 -2.4.2.18 * serratia marcescens 4090.0 4090.0 1 PMID:786623 -2.4.2.18 * thermococcus kodakarensis 1580.0 1580.0 1 PMID:28781961 -2.4.2.19 * bos taurus 0.073 0.073 1 PMID:14165928 -2.4.2.19 * homo sapiens 0.09 0.0187 3 PMID:17868694;PMID:3139649 -2.4.2.19 * mycobacterium tuberculosis 1.2 0.7 2 PMID:24949952 -2.4.2.19 * pseudomonas sp. 0.88 0.88 1 * -2.4.2.19 * rattus norvegicus 0.01235 0.01235 1 PMID:3926003 -2.4.2.19 * ricinus communis 0.75 0.75 1 PMID:4422841 -2.4.2.19 * salmonella enterica subsp. enterica serovar typhimurium 1.2 0.9 3 PMID:20047306;PMID:8419294 -2.4.2.19 * sus scrofa 0.091 0.051695000000000005 4 PMID:4826469;PMID:7357010;PMID:7374514 -2.4.2.2 * aneurinibacillus migulanus 28.4 28.4 1 PMID:28871515 -2.4.2.2 * brevibacillus borstelensis 98.3 98.3 1 PMID:28871515 -2.4.2.2 * escherichia coli 45.0 45.0 1 * -2.4.2.2 * geobacillus stearothermophilus 99.6 99.6 1 * -2.4.2.2 * haemophilus influenzae 205.0 115.25 2 PMID:308598;PMID:8782414 -2.4.2.2 * lacticaseibacillus paracasei 37.5 37.5 1 PMID:28871515 -2.4.2.2 * parageobacillus thermoglucosidasius 0.46 0.46 1 * -2.4.2.2 * serratia marcescens 43.3 43.3 1 PMID:28871515 -2.4.2.2 * siminovitchia fordii 55.8 55.8 1 PMID:28871515 -2.4.2.2 * streptococcus pyogenes 11.2 8.1 3 PMID:21707079 -2.4.2.20 * bos taurus 0.497 0.497 1 PMID:14235538 -2.4.2.21 * acetoanaerobium sticklandii 2.3 2.3 1 PMID:4238408 -2.4.2.21 * propionibacterium freudenreichii subsp. shermanii 11.6 11.6 1 PMID:14253445 -2.4.2.21 * salmonella enterica 30.0 30.0 1 PMID:19880598 -2.4.2.21 * salmonella enterica subsp. enterica serovar typhimurium 0.035 0.0025 3 PMID:12686640 -2.4.2.21 * sporomusa ovata 0.00016 9.88e-05 2 PMID:23039029 -2.4.2.22 * enterococcus faecalis 3.65 3.65 1 PMID:4216296 -2.4.2.22 * thermus thermophilus 1.7 0.12 3 * -2.4.2.24 * arabidopsis thaliana 2.18e-05 2.18e-05 1 PMID:17938130 -2.4.2.24 * hordeum vulgare 0.002 0.0010375 2 * -2.4.2.26 * homo sapiens 0.0285 0.002333 3 PMID:11087729;PMID:19100717 -2.4.2.26 * rattus norvegicus 0.419 0.419 1 PMID:10929006 -2.4.2.28 * arabidopsis thaliana 11.5 1.915 16 PMID:18342331 -2.4.2.28 * bos taurus 10.3 10.3 1 PMID:2108157 -2.4.2.28 * caldariella acidophila 2.48 2.4699999999999998 2 PMID:118001 -2.4.2.28 * homo sapiens 10.2 0.465 6 PMID:105725;PMID:1903946;PMID:3091600;PMID:7732755;PMID:8687427 -2.4.2.28 * pyrococcus furiosus 6.35 6.35 1 PMID:12664268 -2.4.2.28 * rattus norvegicus 0.0283 0.0234 3 PMID:114225;PMID:5378381 -2.4.2.28 * saccharolobus solfataricus 6.27 2.12 5 PMID:10336870;PMID:26116147;PMID:7929153 -2.4.2.28 * trypanosoma brucei brucei 0.365 0.21000000000000002 4 PMID:9920289 -2.4.2.3 * acholeplasma laidlawii 129.0 129.0 1 PMID:6619095 -2.4.2.3 * escherichia coli 230.0 133.0 5 PMID:1610370;PMID:16751;PMID:6356978;PMID:769833;PMID:7730307 -2.4.2.3 * haemophilus influenzae 510.0 510.0 1 PMID:5316215 -2.4.2.3 * homo sapiens 7.7 7.7 1 PMID:20226755 -2.4.2.3 * klebsiella aerogenes 97.83 97.83 1 * -2.4.2.3 * lacticaseibacillus casei 4278.0 3544.0 2 PMID:2119230 -2.4.2.3 * mus musculus 636.0 362.8 2 PMID:7744869;PMID:9850074 -2.4.2.3 * rattus norvegicus 53.0 27.7 2 PMID:13449076;PMID:692394 -2.4.2.3 * trypanosoma brucei 2.75 2.0949999999999998 2 PMID:20070944 -2.4.2.30 * bacillus cereus 22.25 22.25 1 PMID:12911311 -2.4.2.30 * dictyostelium discoideum 0.0017 0.0017 1 * -2.4.2.30 * hathewaya limosa 80.0 80.0 1 PMID:16411778 -2.4.2.30 * helix pomatia 0.0545 0.0545 1 PMID:3124818 -2.4.2.30 * homo sapiens 1.02 0.6725 2 PMID:2434482;PMID:3109898 -2.4.2.30 * saccharolobus solfataricus 83.0 83.0 1 PMID:9761745 -2.4.2.31 * meleagris gallopavo 353.0 53.0 3 PMID:3099839;PMID:6436644 -2.4.2.31 * oryctolagus cuniculus 14.0 7.66 2 PMID:1454819;PMID:8431475 -2.4.2.37 * rhodospirillum rubrum 0.077 0.0405 2 PMID:2504283;PMID:3141411 -2.4.2.38 * arabidopsis thaliana 0.33 0.33 1 PMID:12770780 -2.4.2.38 * glycine max 7e-06 7e-06 1 PMID:9395463 -2.4.2.4 * escherichia coli 155.0 122.0 3 PMID:14235545;PMID:236298;PMID:357904 -2.4.2.4 * homo sapiens 18480.0 4.3 19 PMID:14235545;PMID:15893964;PMID:17949350;PMID:20151198;PMID:2119230;PMID:24407036;PMID:30138393;PMID:718961;PMID:7284378 -2.4.2.4 * lacticaseibacillus casei 1100.0 605.5 2 PMID:14235545;PMID:2119230 -2.4.2.4 * mus musculus 0.00946 0.00067 9 PMID:19028666 -2.4.2.4 * rattus norvegicus 18.0 18.0 1 PMID:14235545 -2.4.2.4 * salmonella enterica subsp. enterica serovar typhimurium 465.0 465.0 1 PMID:1094953;PMID:357903 -2.4.2.40 * phaseolus vulgaris 0.0049 0.0049 1 PMID:16593839 -2.4.2.42 * bos taurus 0.075 0.075 1 PMID:17317689 -2.4.2.48 * methanocaldococcus jannaschii 134.0 134.0 1 PMID:10862614 -2.4.2.48 * methanosarcina acetivorans 31.0 29.0 2 PMID:23201278 -2.4.2.54 * archaeoglobus fulgidus 0.29 0.29 1 PMID:12142414 -2.4.2.54 * methanocaldococcus jannaschii 0.248 0.248 1 PMID:15262968 -2.4.2.54 * methanosarcina thermophila 0.075 0.0525 2 PMID:12142414;PMID:9698382 -2.4.2.54 * methanothermobacter thermautotrophicus 0.36 0.180065 2 PMID:31663056 -2.4.2.55 * sporomusa ovata 0.019 0.019 1 PMID:21696461 -2.4.2.57 * thermococcus kodakarensis 37.5 10.8 9 PMID:17303759;PMID:23065974;PMID:23659790 -2.4.2.6 * lactobacillus helveticus 60.0 15.425 6 PMID:1082813;PMID:30803783;PMID:4548670;PMID:5156378 -2.4.2.6 * lactobacillus leichmannii 173.0 3.6 15 PMID:18487606;PMID:8839981 -2.4.2.6 * lactococcus lactis 6.67 6.67 1 PMID:17881307 -2.4.2.6 * limosilactobacillus fermentum 83.7 0.125 26 PMID:18487606;PMID:18776470 -2.4.2.6 * trypanosoma brucei brucei 47.5 16.2 10 PMID:31264760 -2.4.2.7 * arabidopsis thaliana 300.0 300.0 1 * -2.4.2.7 * artemia sp. 14.2 14.2 1 PMID:1850982 -2.4.2.7 * brassica juncea 9.15 9.15 1 PMID:2275559 -2.4.2.7 * catharanthus roseus 0.156 0.156 1 * -2.4.2.7 * escherichia coli 14.0 14.0 1 PMID:357906 -2.4.2.7 * francisella tularensis subsp. tularensis 1.15 1.15 1 PMID:29694705 -2.4.2.7 * halobacterium salinarum 2050.0 2050.0 1 PMID:9457844 -2.4.2.7 * haloferax volcanii 1430.0 1430.0 1 PMID:9457844 -2.4.2.7 * hevea brasiliensis 2.2 2.2 1 * -2.4.2.7 * homo sapiens 21.8 4.79365 4 PMID:19342420;PMID:19565499;PMID:4349039;PMID:457664;PMID:692402 -2.4.2.7 * leishmania donovani 2.8 2.8 1 PMID:7356667 -2.4.2.7 * mus musculus 20.6 20.6 1 PMID:3768421 -2.4.2.7 * plasmodium falciparum 4e-08 4e-08 1 PMID:2665821 -2.4.2.7 * rattus norvegicus 1.1 1.1 1 PMID:236779;PMID:692403 -2.4.2.7 * saccharomyces cerevisiae 15.14 15.14 1 PMID:7660983 -2.4.2.7 * schizosaccharomyces pombe 18.0 18.0 1 PMID:20306 -2.4.2.7 * thermus thermophilus 785.0 103.0 7 PMID:30640018 -2.4.2.7 * triticum aestivum 0.0413 0.0413 1 PMID:7092211 -2.4.2.8 * artemia sp. 0.65 0.65 1 PMID:1850982 -2.4.2.8 * bos taurus 0.39 0.39 1 * -2.4.2.8 * caldanaerobacter subterraneus subsp. tengcongensis 1.8 1.8 1 PMID:14965769 -2.4.2.8 * cricetulus griseus 9.0 9.0 1 PMID:4368495;PMID:692400 -2.4.2.8 * cryptosporidium parvum 0.346 0.28 3 PMID:9603483 -2.4.2.8 * gallus gallus 705.0 701.55 2 PMID:3996588 -2.4.2.8 * halobacterium salinarum 2340.0 1605.0 2 PMID:9457844 -2.4.2.8 * haloferax volcanii 2450.0 2290.0 2 PMID:9457844 -2.4.2.8 * homo sapiens 46.0 0.42 14 PMID:10029307;PMID:10833458;PMID:19342420;PMID:19565499;PMID:27375492;PMID:692400;PMID:861217;PMID:9132023 -2.4.2.8 * methanococcus voltae 0.0027 0.001775 2 PMID:8626317 -2.4.2.8 * mus musculus 3.0 3.0 1 PMID:237883 -2.4.2.8 * mycobacterium tuberculosis 2524.0 1.44 3 PMID:19362594;PMID:28082125 -2.4.2.8 * plasmodium falciparum 5.4 1.4 9 PMID:10029307;PMID:10833458;PMID:15819884;PMID:17097304 -2.4.2.8 * schistosoma mansoni 13.25 7.85 6 PMID:2199439;PMID:3941107 -2.4.2.8 * schizosaccharomyces pombe 5.75 5.75 1 PMID:20306 -2.4.2.8 * streptomyces cyanogenus 66.5 66.5 1 * -2.4.2.8 * tursiops truncatus 0.0007 0.0007 1 PMID:27375492 -2.4.2.8 * zobellia galactanivorans 0.53 0.5 2 PMID:32671046 -2.4.2.9 * [bacillus] caldolyticus 19.2 9.645 2 PMID:9268683 -2.4.2.9 * acholeplasma laidlawii 0.22 0.22 1 PMID:6619094 -2.4.2.9 * bacillus subtilis 0.07 0.07 1 PMID:9268683 -2.4.2.9 * candida albicans 0.068 0.068 1 PMID:8047103 -2.4.2.9 * escherichia coli 11.4 7.051 4 PMID:3513846;PMID:8856065 -2.4.2.9 * giardia duodenalis 3.1 3.1 1 PMID:7622327 -2.4.2.9 * lactobacillus bifidus 0.025 0.025 1 * -2.4.2.9 * lactobacillus leichmannii 0.0067 0.006200000000000001 2 PMID:5063073 -2.4.2.9 * mycobacterium tuberculosis 1.56 1.1600000000000001 2 PMID:23424660 -2.4.2.9 * saccharolobus shibatae 0.138 0.138 1 PMID:8765224 -2.4.3.1 * bos taurus 26.0 13.00045 2 PMID:4723915;PMID:849932 -2.4.3.1 * capra hircus 0.0035 0.0035 1 PMID:4723915 -2.4.3.1 * homo sapiens 1.6 1.6 1 PMID:12763019 -2.4.3.1 * mus musculus 8e-07 8e-07 1 PMID:8001013 -2.4.3.1 * photobacterium damselae 5.5 5.5 1 PMID:8864851 -2.4.3.1 * photobacterium leiognathi 82.9 5.5 3 PMID:19797322 -2.4.3.1 * photobacterium sp. 113.0 113.0 1 PMID:17984122 -2.4.3.1 * rattus norvegicus 8.2 0.016 5 PMID:19500344;PMID:4313609;PMID:7142179;PMID:8428623 -2.4.3.2 * cichlidae 3.3e-06 2.58e-06 2 PMID:8158143 -2.4.3.2 * rattus norvegicus 0.0084 0.0084 1 PMID:2262006 -2.4.3.3 * bos taurus 28.3 0.00435 3 PMID:4019457;PMID:6639963 -2.4.3.3 * ovis aries 0.00435 0.002325 2 PMID:4723916;PMID:6639963 -2.4.3.3 * rattus norvegicus 0.0003 0.0003 1 PMID:6639963 -2.4.3.3 * sus scrofa 44.6 22.300150000000002 2 PMID:447688;PMID:6639963 -2.4.3.5 * rattus norvegicus 8.2 4.10018 2 PMID:7142179 -2.4.3.6 * photobacterium sp. jt-ish-224 113.0 113.0 1 PMID:17984122 -2.4.3.8 * rattus norvegicus 0.0189 0.00105 3 PMID:2302211;PMID:3115774;PMID:7407216 -2.4.3.9 * homo sapiens 0.0006048 4.5e-06 5 PMID:15061693;PMID:19415461;PMID:4022 -2.4.3.9 * oreochromis mossambicus 2.7e-06 2.7e-06 1 PMID:8158143 -2.4.3.9 * rattus norvegicus 0.0094 0.0055 3 PMID:1999428;PMID:8158143;PMID:8253749 -2.4.99.12 * escherichia coli 20.39 20.39 1 PMID:1577828 -2.4.99.13 * escherichia coli 20.39 20.39 1 PMID:1577828 -2.4.99.16 * mycolicibacterium smegmatis 0.76 0.76 1 PMID:20118231 -2.4.99.18 * canis lupus familiaris 0.000985 0.000985 1 PMID:1555242 -2.4.99.20 * mus musculus 0.4 9e-07 4 PMID:11829748 -2.4.99.23 * escherichia coli 4.9 4.9 1 PMID:9446588 -2.4.99.26 * pseudomonas aeruginosa 0.087 0.087 1 PMID:17697256 -2.5.1.10 * bacillus subtilis 0.0012 0.0012 1 PMID:6792191 -2.5.1.10 * gallus gallus 1.85 1.85 1 PMID:3894878 -2.5.1.10 * geobacillus stearothermophilus 4.69 3.6500000000000004 2 PMID:7918490 -2.5.1.10 * homo sapiens 0.922 0.922 1 PMID:4021811 -2.5.1.10 * ricinus communis 0.06 0.05 2 PMID:4371817 -2.5.1.10 * saccharomyces cerevisiae 2.33 2.33 1 PMID:3894878 -2.5.1.104 * thermus thermophilus 2.4 2.4 1 PMID:15983049 -2.5.1.126 * pyrobaculum aerophilum 0.14 0.071 4 PMID:19822146 -2.5.1.127 * hyperthermus butylicus 0.112 0.041 4 PMID:19822146 -2.5.1.128 * thermococcus kodakarensis 0.34 0.23 2 PMID:24610711 -2.5.1.132 * oncorhynchus mykiss 0.0009 0.0009 1 PMID:10438460 -2.5.1.144 * salmonella enterica subsp. enterica serovar typhimurium 276.6 138.365 2 PMID:6373737 -2.5.1.145 * lactococcus lactis 0.2972 0.15603 2 PMID:23165241 -2.5.1.15 * escherichia coli 30.0 1.0 3 PMID:385600;PMID:4304228;PMID:9650994 -2.5.1.15 * escherichia coli mc4100 3.7 3.7 1 PMID:1657875 -2.5.1.15 * lathyrus oleraceus 0.425 0.425 1 PMID:9118956 -2.5.1.15 * mycobacterium leprae 0.174 0.174 1 PMID:10542185 -2.5.1.15 * mycobacterium tuberculosis 0.596 0.577 3 PMID:10542185;PMID:18680522 -2.5.1.15 * plasmodium chabaudi 15.78 15.78 1 PMID:4435732;PMID:7374502 -2.5.1.15 * plasmodium falciparum 0.0106 0.0106 1 PMID:15279950 -2.5.1.15 * saccharomyces cerevisiae 1.25 1.25 1 PMID:15866722 -2.5.1.15 * streptococcus pneumoniae 0.29 0.29 1 PMID:10329458 -2.5.1.152 * staphylococcus aureus 3.2 3.2 1 PMID:29091735 -2.5.1.16 * bos taurus 1.12 0.916 2 PMID:6312269;PMID:6743257 -2.5.1.16 * brassica rapa subsp. pekinensis 1.28 1.175 2 PMID:16664325 -2.5.1.16 * caenorhabditis elegans 1.8 1.8 1 PMID:16226262 -2.5.1.16 * escherichia coli 1.83 1.83 1 PMID:4572733;PMID:6312268 -2.5.1.16 * glycine max 0.076 0.076 1 PMID:10806333 -2.5.1.16 * homo sapiens 0.66 0.66 1 PMID:2730590 -2.5.1.16 * rattus norvegicus 1.3 0.055 3 PMID:6312269;PMID:7103507;PMID:7396502;PMID:7396856 -2.5.1.160 * arabidopsis thaliana 21.0 10.625 2 * -2.5.1.17 * bos taurus 0.047 0.047 2 PMID:12514191 -2.5.1.17 * homo sapiens 0.49 0.098 11 PMID:12514191;PMID:15347655;PMID:16439175;PMID:19933577 -2.5.1.17 * lactobacillus leichmannii 0.000125 0.000125 2 PMID:7366442 -2.5.1.17 * limosilactobacillus reuteri 0.25 0.045 5 PMID:18452306;PMID:19933577 -2.5.1.17 * methanosarcina mazei 0.001 0.001 1 PMID:16672609 -2.5.1.17 * pseudomonas denitrificans (nom. rej.) 0.18 0.135 8 PMID:1917862 -2.5.1.17 * salmonella enterica 0.262 0.091 5 PMID:15317775;PMID:15547259;PMID:15954777;PMID:16207720 -2.5.1.17 * salmonella enterica subsp. enterica serovar typhimurium 0.312 0.053 5 PMID:11160088;PMID:15317775;PMID:7860601 -2.5.1.17 * thermoplasma acidophilum 0.742 0.6005 6 PMID:15044458 -2.5.1.18 * acidovorax sp. kks102 1.0628 0.1396 5 PMID:29779193 -2.5.1.18 * acipenser transmontanus 77.7 73.1 2 PMID:15670627 -2.5.1.18 * alitta succinea 6.082 6.082 1 PMID:17459495 -2.5.1.18 * anopheles dirus 58.6 0.079 5 PMID:18760991 -2.5.1.18 * apis mellifera 0.4 0.4 1 * -2.5.1.18 * arabidopsis thaliana 3.83 1.94 2 PMID:27718072 -2.5.1.18 * ascaris suum 38.2 0.312 3 * -2.5.1.18 * aspergillus nidulans 0.09 0.048799999999999996 2 PMID:19171936 -2.5.1.18 * atactodea striata 108.9 108.9 1 PMID:12893269 -2.5.1.18 * bombyx mori 4610.0 25.6 3 PMID:15950511 -2.5.1.18 * bos taurus 26.6 2.3 11 PMID:18211812;PMID:18356169;PMID:6725231;PMID:7126177 -2.5.1.18 * brucella anthropi 5.9 5.9 1 PMID:18076047 -2.5.1.18 * canis lupus familiaris 0.146 0.146 1 PMID:16891247 -2.5.1.18 * chlamys islandica 300.6 300.6 1 * -2.5.1.18 * cucurbita maxima 0.323 0.323 1 * -2.5.1.18 * cyphoma gibbosum 75.0 75.0 2 PMID:18671936 -2.5.1.18 * danio rerio 0.04483 0.04483 1 PMID:28621814 -2.5.1.18 * drosophila melanogaster 74.0 36.0 3 PMID:29578047 -2.5.1.18 * echinococcus granulosus 2.5 2.5 1 PMID:20034460 -2.5.1.18 * enterobacter cloacae 3.47 3.47 1 PMID:2614380 -2.5.1.18 * escherichia coli 1.01 0.885 2 PMID:2614380 -2.5.1.18 * fasciola gigantica 105.45 9.120000000000001 6 PMID:29235505;PMID:32663558 -2.5.1.18 * gallus gallus 20.39 0.79 6 PMID:19247857;PMID:7469418 -2.5.1.18 * glycine max 4.9 2.462 2 * -2.5.1.18 * haliotis discus 1.06 0.215 4 PMID:18703158 -2.5.1.18 * hippocampus abdominalis 21.03 5.35 5 PMID:28882453 -2.5.1.18 * homo sapiens 254.9 7.26 67 PMID:15683365;PMID:15942673;PMID:16891247;PMID:17046132;PMID:17587159;PMID:18211812;PMID:18356169;PMID:18511072;PMID:18796433;PMID:3003505;PMID:3092805;PMID:3663118;PMID:3985982;PMID:4044571;PMID:6173570;PMID:7329301;PMID:7329302;PMID:8108434;PMID:8694853;PMID:907137 -2.5.1.18 * hordeum vulgare 6.0 3.0635 2 PMID:16020429 -2.5.1.18 * hypophthalmichthys molitrix 0.36 0.245 2 PMID:19101655 -2.5.1.18 * klebsiella oxytoca 4.8 4.49 2 PMID:2614380 -2.5.1.18 * lactiplantibacillus plantarum 3980.6 2885.05 2 PMID:32181246 -2.5.1.18 * lactuca sativa 4.03 4.03 1 PMID:15826502 -2.5.1.18 * liposcelis bostrychophila 0.0147 0.0147 1 * -2.5.1.18 * liposcelis entomophila 0.0075 0.0075 1 * -2.5.1.18 * liposcelis paeta 0.0674 0.02575 6 PMID:19140127 -2.5.1.18 * lolium arundinaceum 34.55 0.51 3 PMID:17640691 -2.5.1.18 * lucilia cuprina 14.5 5.37 4 PMID:22100830 -2.5.1.18 * macaca fascicularis 0.318 0.318 1 PMID:16891247 -2.5.1.18 * macaca mulatta 0.41 0.41 1 PMID:411787 -2.5.1.18 * macrobrachium vollenhovenii 12.36 12.36 1 PMID:15674845 -2.5.1.18 * monopterus albus 13.07 13.07 1 * -2.5.1.18 * morone saxatilis 0.141 0.141 1 PMID:17391762 -2.5.1.18 * mus musculus 148.0 74.486 2 PMID:16891247;PMID:3091071 -2.5.1.18 * myathropa florea 1.79 0.96 2 * -2.5.1.18 * oncorhynchus kisutch 31.2 31.2 1 PMID:17184855 -2.5.1.18 * oryza sativa 93.21 82.27 3 PMID:19640724 -2.5.1.18 * ovis aries 20.4 17.45 2 PMID:6870266 -2.5.1.18 * paragonimus westermani 325.0 182.5 2 PMID:17641916 -2.5.1.18 * penaeus vannamei 440.1 440.1 1 PMID:17427177 -2.5.1.18 * pinus tabuliformis 169.1 169.1 1 PMID:15820751 -2.5.1.18 * plasmodium vivax 34.7 0.58 3 PMID:17459379 -2.5.1.18 * plasmodium yoelii 0.78 0.78 1 PMID:17024358 -2.5.1.18 * plutella xylostella 0.041 0.041 2 PMID:30363080 -2.5.1.18 * proteus mirabilis 3.69 0.79 5 PMID:20663851;PMID:2614380 -2.5.1.18 * proteus vulgaris 1.47 1.47 1 PMID:2614380 -2.5.1.18 * pseudomonas aeruginosa 0.74 0.74 1 PMID:2614380 -2.5.1.18 * pseudomonas putida 270.0 270.0 1 PMID:17508726 -2.5.1.18 * rattus norvegicus 130.0 0.702 47 PMID:15952767;PMID:16891247;PMID:17297922;PMID:18211812;PMID:18356169;PMID:19629404;PMID:4025799;PMID:4088071;PMID:4088072;PMID:500691;PMID:6173570;PMID:6661188;PMID:6743313;PMID:6838589;PMID:6884349;PMID:7304969;PMID:86357 -2.5.1.18 * rhodotorula mucilaginosa 60.2 35.35 2 PMID:31669543 -2.5.1.18 * rutilus rutilus 0.74 0.505 2 PMID:19101655 -2.5.1.18 * schistocerca gregaria 42.8 22.729999999999997 2 * -2.5.1.18 * schistosoma japonicum 8.0 8.0 1 PMID:11488926 -2.5.1.18 * serratia marcescens 0.435 0.435 1 PMID:2614380 -2.5.1.18 * setaria cervi 1220.0 9.0 4 PMID:17367761;PMID:18752976 -2.5.1.18 * setaria faberi 29.4 29.4 1 * -2.5.1.18 * solenopsis invicta 85.1 85.1 1 PMID:14505691 -2.5.1.18 * spinacia oleracea 5.2 0.04 6 PMID:27718072 -2.5.1.18 * spodoptera litura 1.8 0.73 6 PMID:29235695 -2.5.1.18 * sus scrofa 124.0 5.75 4 PMID:11485575;PMID:6654851 -2.5.1.18 * synechococcus elongatus 102.0 5.26 11 PMID:17484723 -2.5.1.18 * syrphus ribesii 3.07 2.17 2 * -2.5.1.18 * taenia crassiceps 26.9 1.5 10 PMID:29032785 -2.5.1.18 * taenia solium 78.0 0.7 15 PMID:15127293;PMID:17704948;PMID:18662665 -2.5.1.18 * tetranychus urticae 15.94 0.34 9 PMID:26047112 -2.5.1.18 * thermosynechococcus vestitus 33.0 1.54 13 PMID:17484723 -2.5.1.18 * triticum aestivum 0.000411 0.000411 1 PMID:16835885 -2.5.1.18 * wiseana cervinata 108.0 108.0 1 PMID:6696729 -2.5.1.18 * xylella fastidiosa 3.3 1.8199999999999998 2 PMID:18331799 -2.5.1.18 * zea mays 66.0 21.0 3 PMID:16835885;PMID:6838840 -2.5.1.19 * alcanivorax sp. 7.78 7.78 1 PMID:25039062 -2.5.1.19 * bacillus subtilis 10.4 10.4 1 PMID:7744055 -2.5.1.19 * bacteria 35.9 35.9 1 PMID:18172892 -2.5.1.19 * escherichia coli 62.0 20.55 10 PMID:11731078;PMID:12795593;PMID:12843673;PMID:17855366;PMID:18567546;PMID:3298979;PMID:6229418;PMID:8837736 -2.5.1.19 * klebsiella pneumoniae 37.8 24.33 2 PMID:6381056 -2.5.1.19 * lathyrus oleraceus 12.0 8.82 4 PMID:24258375 -2.5.1.19 * mycobacterium tuberculosis 18.13 11.905 2 PMID:11483005;PMID:12699693 -2.5.1.19 * nicotiana sylvestris 16.9 16.9 1 PMID:16663714 -2.5.1.19 * oryza sativa 10.03 10.03 1 PMID:16361526 -2.5.1.19 * plant 47.5 47.5 1 PMID:18172892 -2.5.1.19 * pseudomonas aeruginosa 8.5 2.0 5 * -2.5.1.19 * pseudomonas fluorescens 7.24 5.9405 4 PMID:17951442 -2.5.1.19 * salmonella enterica subsp. enterica serovar typhimurium 0.0058 0.0058 2 PMID:11731078;PMID:12843673 -2.5.1.19 * sorghum bicolor 21.1 21.1 1 PMID:16666109 -2.5.1.19 * stutzerimonas stutzeri 0.19 0.19 1 PMID:18368293 -2.5.1.19 * trichormus variabilis 4.07 2.665 2 PMID:24178379 -2.5.1.19 * zea mays 94.7 77.85 2 PMID:12232268 -2.5.1.20 * parthenium argentatum 0.000695 0.000695 1 PMID:16663758 -2.5.1.20 * taraxacum kok-saghyz 3e-06 2.8000000000000003e-06 2 PMID:20170509 -2.5.1.21 * narcissus pseudonarcissus 0.03 0.03 1 PMID:1959622 -2.5.1.21 * nicotiana tabacum 0.164 0.164 1 PMID:16668616 -2.5.1.21 * rattus norvegicus 1.2 0.6799999999999999 2 PMID:1527001;PMID:1569107 -2.5.1.21 * saccharomyces cerevisiae 15.6 0.95 3 PMID:3277535;PMID:3805037 -2.5.1.21 * trypanosoma cruzi 0.459 0.2795 2 PMID:17371809 -2.5.1.22 * bos taurus 0.579 0.403 3 PMID:2843368;PMID:520313;PMID:658433;PMID:6621388 -2.5.1.22 * homo sapiens 2425.0 1212.7275 2 PMID:23468611;PMID:2730590 -2.5.1.22 * rattus norvegicus 0.306 0.1561 2 PMID:4564056;PMID:7396856 -2.5.1.23 * hyperthermus butylicus 0.038 0.02 2 PMID:19822146 -2.5.1.23 * saccharolobus solfataricus 2.059 2.059 1 PMID:3096734 -2.5.1.24 * dictyostelium discoideum 0.0123 0.0123 1 * -2.5.1.26 * cavia porcellus 0.35 0.17856999999999998 2 PMID:1495419;PMID:8399344 -2.5.1.26 * mus musculus 0.067 0.0439 2 PMID:1495418;PMID:6833249;PMID:7096336 -2.5.1.27 * nostoc sp. 0.01122 0.01122 1 PMID:26376297 -2.5.1.29 * bos taurus 0.098 0.051305 2 PMID:8051156;PMID:8407863 -2.5.1.29 * capsicum annuum 0.017 0.017 1 * -2.5.1.29 * hevea brasiliensis 0.123 0.123 1 PMID:12531482 -2.5.1.29 * homo sapiens 0.133 0.133 1 PMID:17208200 -2.5.1.29 * methanothermobacter thermautotrophicus 0.289 0.2145 2 * -2.5.1.29 * micrococcus luteus 0.0182 0.0182 1 PMID:7275954 -2.5.1.29 * phycomyces blakesleeanus 0.3 0.3 1 PMID:3190245 -2.5.1.29 * rattus norvegicus 0.117 0.117 1 PMID:17846065 -2.5.1.29 * sulfolobus acidocaldarius 0.0087 0.0087 1 PMID:8182085 -2.5.1.29 * sus scrofa 2.79e-05 2.79e-05 1 PMID:4021812 -2.5.1.29 * taxus baccata 13.8 13.8 1 PMID:10717315 -2.5.1.3 * escherichia coli 0.7 0.38249999999999995 2 PMID:22226942;PMID:374983;PMID:4580841 -2.5.1.3 * saccharomyces cerevisiae 0.269 0.269 1 PMID:8394314 -2.5.1.3 * zea mays 2.46 0.52 3 PMID:17696876 -2.5.1.31 * bacillus subtilis 0.000424 0.000424 1 PMID:6818223 -2.5.1.31 * escherichia coli 2.5 1.2565 2 PMID:10978182 -2.5.1.31 * micrococcus luteus 1.534 0.769033 2 PMID:7436416;PMID:9677368 -2.5.1.32 * capsicum annuum 0.067 0.067 1 PMID:16578835 -2.5.1.34 * claviceps purpurea 0.5 0.5 1 PMID:1605639 -2.5.1.34 * claviceps sp. 0.35 0.3295 2 PMID:4021819;PMID:7287742;PMID:999297 -2.5.1.35 * aspergillus terreus 0.0294 0.0294 1 PMID:4021817;PMID:678538 -2.5.1.39 * escherichia coli 0.014 0.0013 3 PMID:8155731 -2.5.1.44 * acinetobacter tartarogenes 8.41 8.41 1 PMID:8407874 -2.5.1.44 * blastochloris viridis 4.97 2.7849999999999997 2 PMID:8841401 -2.5.1.44 * lathyrus sativus 0.00025 0.00025 1 PMID:7470060 -2.5.1.44 * santalum album 0.0038 0.0038 1 PMID:7470060 -2.5.1.45 * distimake quinquefolius 0.138 0.138 1 PMID:23572540 -2.5.1.45 * eupatorium cannabinum 0.047 0.0238 2 * -2.5.1.45 * ipomoea alba 0.047 0.047 1 PMID:23572540 -2.5.1.45 * ipomoea hederifolia 0.136 0.136 1 PMID:23572540 -2.5.1.45 * ipomoea meyeri 0.138 0.138 1 PMID:23572540 -2.5.1.45 * ipomoea neei 0.062 0.062 1 PMID:23572540 -2.5.1.46 * homo sapiens 0.019 0.015 3 PMID:7673224;PMID:7750572 -2.5.1.46 * leishmania donovani 9.6e-06 9.6e-06 1 PMID:19880510 -2.5.1.46 * nicotiana tabacum 0.0211 0.0091 3 PMID:10542236 -2.5.1.46 * rattus norvegicus 0.000137 0.000137 1 PMID:2108161 -2.5.1.46 * saccharomyces cerevisiae 0.0131 0.0131 1 PMID:7629166 -2.5.1.46 * senecio vernalis 0.0442 0.02715 2 PMID:10611289 -2.5.1.47 * acidithiobacillus ferrooxidans atcc 23270 5.0 5.0 1 PMID:20033172 -2.5.1.47 * aeropyrum pernix 50.9 48.45 2 PMID:12644499;PMID:22580223 -2.5.1.47 * allium tuberosum 1.36 1.185 2 * -2.5.1.47 * allochromatium vinosum 245.6 124.015 2 * -2.5.1.47 * arabidopsis thaliana 900.0 590.0 3 PMID:15258168 -2.5.1.47 * azospirillum brasilense 172.3 172.3 1 PMID:16907731 -2.5.1.47 * brassica juncea 410.0 410.0 1 * -2.5.1.47 * capsicum annuum 400.0 400.0 1 PMID:1381358 -2.5.1.47 * chlamydomonas reinhardtii 336.0 41.15 3 * -2.5.1.47 * chlorella sorokiniana 149.0 149.0 1 PMID:25093930 -2.5.1.47 * citrullus lanatus 691.0 670.0 2 * -2.5.1.47 * corynebacterium glutamicum 435.0 435.0 1 PMID:15277766 -2.5.1.47 * datura inoxia 880.0 880.0 1 PMID:8119966 -2.5.1.47 * escherichia coli 728.0 150.0 5 PMID:16546401;PMID:2122244;PMID:25779754 -2.5.1.47 * glycine max 0.724 0.45399999999999996 4 * -2.5.1.47 * hordeum vulgare 5500.0 5500.0 1 * -2.5.1.47 * lathyrus oleraceus 933.0 892.5 2 * -2.5.1.47 * leishmania major 180.0 180.0 1 PMID:22750854 -2.5.1.47 * methanosarcina thermophila 0.129 0.129 1 PMID:10613861 -2.5.1.47 * microcystis aeruginosa 412.0 323.5 2 PMID:24275508 -2.5.1.47 * raphanus sativus 1024.0 1024.0 1 * -2.5.1.47 * rhodocyclus tenuis 143.0 136.5 2 PMID:6615127 -2.5.1.47 * saccharomyces cerevisiae 25.2 0.8045 4 PMID:4609980;PMID:7007360;PMID:7021536;PMID:795806 -2.5.1.47 * salmonella enterica subsp. enterica serovar typhimurium 1100.0 303.0 3 PMID:4891157;PMID:6373737 -2.5.1.47 * spinacia oleracea 1431.0 688.5 6 PMID:1375015;PMID:7669816;PMID:9571779 -2.5.1.47 * thermus thermophilus 337.4 337.4 1 PMID:12005048 -2.5.1.47 * trichomonas vaginalis 180.0 139.25 2 PMID:16735516 -2.5.1.47 * trifolium repens 1.91 1.91 1 * -2.5.1.47 * triticum aestivum 5.7 5.7 1 * -2.5.1.48 * corynebacterium glutamicum 37.0 20.35 2 PMID:10420990 -2.5.1.48 * escherichia coli 10.0 9.5 2 PMID:2405903;PMID:6361021 -2.5.1.48 * helicobacter pylori 0.403 0.403 1 PMID:17981822 -2.5.1.48 * lysinibacillus sphaericus 118.0 118.0 1 PMID:3816790 -2.5.1.48 * salmonella enterica subsp. enterica serovar typhimurium 18.7 18.2 3 PMID:4893684;PMID:5350958 -2.5.1.48 * spinacia oleracea 13.11 13.11 1 PMID:7840669 -2.5.1.48 * sulfurisphaera tokodaii 1.7 1.2 4 PMID:28291751 -2.5.1.49 * [brevibacterium] flavum 0.00472 0.00472 1 PMID:7096282 -2.5.1.49 * aspergillus nidulans 8.96 6.680000000000001 2 PMID:8249501 -2.5.1.49 * clostridioides difficile 50.0 50.0 1 PMID:31359602 -2.5.1.49 * corynebacterium acetophilum 16.7 8.404 2 PMID:15989 -2.5.1.49 * corynebacterium glutamicum 480.0 63.0 3 PMID:20798582 -2.5.1.49 * geobacillus stearothermophilus 29.9 7.435 6 PMID:16233482 -2.5.1.49 * neurospora crassa 7.7 4.2 3 PMID:5541779 -2.5.1.49 * saccharomyces cerevisiae 30.0 19.2 5 PMID:4609980;PMID:4947307;PMID:795806;PMID:795807 -2.5.1.49 * thermus thermophilus 67.7 2.645 12 PMID:11566369;PMID:15215603 -2.5.1.5 * betaphycus gelatinus 0.1865 0.11216 2 PMID:24632215 -2.5.1.50 * lupinus luteus 0.009 0.009 1 * -2.5.1.51 * citrullus lanatus 0.355 0.355 1 * -2.5.1.52 * leucaena leucocephala 0.189 0.189 1 * -2.5.1.54 * actinosynnema pretiosum subsp. auranticum 0.0127 0.0127 1 PMID:22326798 -2.5.1.54 * amycolatopsis mediterranei 0.91 0.91 1 PMID:2565737 -2.5.1.54 * arachis hypogaea 0.14 0.125 2 * -2.5.1.54 * corynebacterium glutamicum 160.0 149.65 2 PMID:11150666;PMID:11381336 -2.5.1.54 * cupriavidus necator 0.026 0.026 1 PMID:239657 -2.5.1.54 * daucus carota 7.1 4.699999999999999 2 PMID:16664489 -2.5.1.54 * escherichia coli 82.6 17.55 8 PMID:12951;PMID:12964183;PMID:13654249;PMID:1672127;PMID:26682;PMID:821531;PMID:9056491;PMID:9387 -2.5.1.54 * kitasatospora aureofaciens 1.3 1.3 1 PMID:5003718 -2.5.1.54 * lathyrus oleraceus 18.8 18.8 1 * -2.5.1.54 * neurospora crassa 8.1 6.1 4 PMID:6119978 -2.5.1.54 * pseudomonas aeruginosa 0.056 0.0305 2 PMID:6127340 -2.5.1.54 * saccharomyces cerevisiae 8.24 8.24 1 PMID:9575238 -2.5.1.54 * salmonella enterica subsp. enterica serovar typhimurium 37.5 28.0 2 PMID:12135;PMID:4572729 -2.5.1.54 * schizosaccharomyces pombe 10.75 10.75 1 PMID:21700 -2.5.1.54 * solanum tuberosum 16.4 16.4 1 PMID:16665132 -2.5.1.54 * streptomyces coelicolor 8.33 8.33 1 * -2.5.1.54 * streptomyces rimosus 11.02 9.41 2 PMID:8094298 -2.5.1.54 * vigna radiata 0.21 0.109 2 PMID:16664478 -2.5.1.54 * xanthomonas campestris 3.11 2.4 3 PMID:11395471 -2.5.1.55 * aquifex aeolicus 3.38 3.38 1 PMID:10491295 -2.5.1.55 * aquifex pyrophilus 7.2 7.2 1 PMID:12955602 -2.5.1.55 * escherichia coli 3.7 3.7 1 PMID:6988389;PMID:7048004 -2.5.1.55 * neisseria meningitidis 12.0 2.0 3 PMID:18930408;PMID:19447118 -2.5.1.55 * pseudomonas aeruginosa 0.038 0.038 1 PMID:14416200 -2.5.1.56 * campylobacter jejuni 1.018 1.018 1 PMID:15200387 -2.5.1.56 * escherichia coli 487.0 28.11 3 PMID:28780284;PMID:9254051;PMID:9438985 -2.5.1.56 * neisseria meningitidis 0.06 0.06 1 PMID:13971393 -2.5.1.57 * homo sapiens 11.7 0.26 3 PMID:18304454;PMID:5928202 -2.5.1.57 * rattus norvegicus 0.505 0.505 1 PMID:11886839 -2.5.1.57 * sus scrofa 0.83 0.10075 4 PMID:13743311;PMID:5928202 -2.5.1.58 * bos taurus 0.0207 0.0207 1 * -2.5.1.58 * rattus norvegicus 0.0085 0.0085 1 PMID:8486655 -2.5.1.58 * saccharomyces cerevisiae 0.867 0.867 1 * -2.5.1.58 * solanum lycopersicum 0.08 0.08 1 PMID:8883388 -2.5.1.58 * trypanosoma brucei brucei 13.5 13.5 1 PMID:9756885 -2.5.1.59 * bos taurus 0.0059 0.0059 1 PMID:8440698 -2.5.1.59 * rattus norvegicus 0.007 0.007 1 PMID:8089111 -2.5.1.6 * atriplex nummularia 0.109 0.109 1 PMID:15695433 -2.5.1.6 * bos taurus 12.4 12.4 1 PMID:3403522 -2.5.1.6 * cryptosporidium parvum 4400.0 4400.0 1 PMID:12951252 -2.5.1.6 * escherichia coli 1.828 0.75 5 PMID:24154832;PMID:31307578;PMID:6137755;PMID:6251075 -2.5.1.6 * homo sapiens 216.0 12.2 3 PMID:12842102;PMID:3980460;PMID:7803470 -2.5.1.6 * leishmania donovani 3000.0 111.1 4 PMID:12492472;PMID:15206944 -2.5.1.6 * mycolicibacterium smegmatis 1.3 1.3 1 PMID:12809568 -2.5.1.6 * pyrococcus furiosus 4.3 4.3 1 PMID:25577347 -2.5.1.6 * rattus norvegicus 110000.0 3.805 14 PMID:10873534;PMID:12496263;PMID:3093473;PMID:3121322;PMID:7213623 -2.5.1.6 * saccharolobus solfataricus 0.138 0.1015 2 PMID:3142771 -2.5.1.6 * saccharomyces cerevisiae 23.83 11.0 5 PMID:18078345;PMID:194884 -2.5.1.6 * sus scrofa 0.0431 0.00415 6 PMID:19474158 -2.5.1.6 * trypanosoma brucei brucei 0.00278 0.00278 1 PMID:8457607 -2.5.1.60 * rattus norvegicus 0.098 0.064 2 PMID:11388804;PMID:1321151 -2.5.1.60 * saccharomyces cerevisiae 0.0082 0.0082 1 PMID:8756702 -2.5.1.61 * arabidopsis thaliana 0.073 0.073 1 * -2.5.1.61 * cereibacter sphaeroides 0.45 0.45 1 PMID:4542566 -2.5.1.61 * chlorella regularis 0.0058 0.0058 1 PMID:7213640 -2.5.1.61 * euglena gracilis 0.1 0.1 1 PMID:6796041 -2.5.1.61 * homo sapiens 0.0402 0.023 9 PMID:17298218;PMID:19207107;PMID:1925827;PMID:2609111;PMID:3390155;PMID:7354069 -2.5.1.61 * lathyrus oleraceus 0.0813 0.0813 1 PMID:1986793 -2.5.1.61 * nitratidesulfovibrio vulgaris 0.333 0.333 1 PMID:19267692 -2.5.1.61 * tetradesmus obliquus 0.113 0.113 1 * -2.5.1.63 * actinopolyspora mzabensis 0.44 0.44 1 PMID:31589919 -2.5.1.65 * aeropyrum pernix 245.0 54.5 5 PMID:12644499;PMID:12965218;PMID:16005886;PMID:22580223 -2.5.1.67 * tanacetum cinerariifolium 0.00267 0.00267 1 PMID:11287653 -2.5.1.68 * mycobacterium tuberculosis 0.0014 0.0009500000000000001 4 PMID:10816587;PMID:11152452 -2.5.1.7 * enterobacter cloacae 1.9 0.9 5 PMID:1123336;PMID:1150648;PMID:1577165;PMID:5699062 -2.5.1.7 * haemophilus influenzae 4.7 4.7 1 * -2.5.1.7 * staphylococcus epidermidis 0.2 0.2 1 PMID:4688141 -2.5.1.70 * sophora flavescens 0.001 0.001 1 PMID:14551337 -2.5.1.71 * sophora flavescens 0.06 0.03007 2 PMID:14551337 -2.5.1.72 * bacillus subtilis 0.05 0.0385 2 PMID:18959769 -2.5.1.72 * escherichia coli 0.6 0.6 1 PMID:10648170 -2.5.1.75 * escherichia coli 1.15 0.6014999999999999 2 PMID:4341485;PMID:9012675 -2.5.1.76 * methanosarcina acetivorans 0.015 0.015 1 PMID:19761441 -2.5.1.78 * aquifex aeolicus 0.031 0.031 1 PMID:12603336 -2.5.1.78 * brucella sp. 0.018 0.018 1 PMID:16923880 -2.5.1.78 * candida albicans 0.166 0.166 1 PMID:17446177 -2.5.1.78 * escherichia coli 11.8 11.8 1 PMID:8969176 -2.5.1.78 * methanocaldococcus jannaschii 0.011 0.011 1 PMID:12603336 -2.5.1.78 * mycobacterium tuberculosis 0.113 0.113 1 PMID:19552377 -2.5.1.78 * saccharomyces cerevisiae 15.4 15.4 1 PMID:8969176 -2.5.1.78 * schizosaccharomyces pombe 13.0 0.266 3 PMID:11856310;PMID:17348709;PMID:19552377 -2.5.1.78 * spinacia oleracea 16.5 16.5 1 PMID:10419541 -2.5.1.79 * thalassiosira pseudonana 0.313 0.313 1 PMID:19075322 -2.5.1.84 * micrococcus luteus 0.073 0.036893499999999996 2 PMID:1748647;PMID:4021815 -2.5.1.9 * bacillus subtilis 0.833 0.033 5 PMID:3145341;PMID:416855;PMID:6766130 -2.5.1.9 * eremothecium ashbyi 1.2 0.6799999999999999 2 PMID:4612121;PMID:6768961 -2.5.1.9 * eremothecium gossypii 0.266 0.266 1 PMID:13944006 -2.5.1.9 * escherichia coli 0.003 0.0022 2 PMID:13944006;PMID:416855 -2.5.1.9 * geobacillus stearothermophilus 0.011 0.011 1 PMID:25043 -2.5.1.9 * methanocaldococcus jannaschii 0.024 0.016 6 PMID:15381435;PMID:16042598 -2.5.1.9 * methanothermobacter thermautotrophicus 0.045 0.0385 4 PMID:9139911 -2.5.1.9 * saccharomyces cerevisiae 0.052 0.052 1 PMID:13944006 -2.5.1.9 * schizosaccharomyces pombe 158.0 158.0 1 PMID:14690539 -2.5.1.9 * spinacia oleracea 0.00025 0.00025 1 * -2.5.1.90 * escherichia coli 58000.0 17050.0 4 PMID:29191106 -2.5.1.93 * lithospermum erythrorhizon 4.68 1.32 3 PMID:9640665 -2.6.1.1 * arabidopsis thaliana 2934.0 454.0 3 PMID:9535706 -2.6.1.1 * avena sativa 120.0 120.0 1 PMID:1141216 -2.6.1.1 * bacillus sp. (in: firmicutes) 220.0 220.0 1 PMID:2155199 -2.6.1.1 * bos taurus 136.0 136.0 1 PMID:4708676 -2.6.1.1 * bradyrhizobium japonicum 69.4 69.4 1 * -2.6.1.1 * canis lupus familiaris 341.0 248.5 2 PMID:4673759 -2.6.1.1 * chlamydomonas reinhardtii 84.0 84.0 1 PMID:2331983;PMID:3137225 -2.6.1.1 * cystobasidium minutum 403.4 202.89999999999998 2 PMID:2332417 -2.6.1.1 * dolphin 228.0 164.0 2 PMID:4462740 -2.6.1.1 * eleusine coracana 105.0 105.0 1 PMID:2241160 -2.6.1.1 * escherichia coli 232.0 205.0 4 PMID:17353007;PMID:3003515;PMID:3298223;PMID:374118 -2.6.1.1 * gallus gallus 150.0 74.0 5 PMID:4632248;PMID:926178 -2.6.1.1 * geobacillus thermopakistaniensis 104.0 57.5 2 PMID:32738436 -2.6.1.1 * glycine max 0.576 0.576 1 * -2.6.1.1 * haloferax mediterranei 1.53 1.53 1 * -2.6.1.1 * hyalomma dromedarii 0.061 0.061 1 PMID:11523919 -2.6.1.1 * leptosphaeria michotii 805.6 676.05 2 PMID:2707258 -2.6.1.1 * lupinus angustifolius 105.0 105.0 1 PMID:7294808 -2.6.1.1 * medicago sativa 240.0 140.0 3 PMID:16666973 -2.6.1.1 * megathyrsus maximus 182.0 173.5 2 PMID:2930193 -2.6.1.1 * methanococcus aeolicus 25.3 12.8 2 PMID:1729242 -2.6.1.1 * methanothermobacter thermautotrophicus 21.8 15.120000000000001 2 PMID:1295891 -2.6.1.1 * nostoc sp. 2.417 2.417 1 PMID:25808172 -2.6.1.1 * oryctolagus cuniculus 443.0 337.0 2 PMID:4030726 -2.6.1.1 * oryza sativa 450.0 420.0 2 * -2.6.1.1 * ovis aries 217.0 184.25 2 PMID:35156;PMID:4204952 -2.6.1.1 * panicum miliaceum 1035.0 512.0 7 PMID:7733657 -2.6.1.1 * phormidium lapideum 221.0 110.555 2 PMID:12723595 -2.6.1.1 * pinus pinaster 16.87 8.528 2 PMID:16623902;PMID:17545128 -2.6.1.1 * plasmodium falciparum 2.67 0.24 5 PMID:21087616 -2.6.1.1 * pseudoalteromonas haloplanktis 137.7 75.30999999999999 2 PMID:10785402 -2.6.1.1 * pseudomonas putida 45.15 45.15 1 PMID:1290 -2.6.1.1 * rattus norvegicus 215.0 35.410000000000004 6 PMID:16489927;PMID:17442055;PMID:7426616 -2.6.1.1 * saccharolobus solfataricus 93.0 88.5 2 PMID:1445947;PMID:2331983;PMID:3137225 -2.6.1.1 * spirodela polyrhiza 1.41 0.2495 4 * -2.6.1.1 * sus scrofa 170.0 170.0 1 PMID:1278171 -2.6.1.1 * thermus thermophilus 112.1 112.1 1 PMID:8907187 -2.6.1.1 * torulopsis candida 292.3 2.5 3 PMID:2332417 -2.6.1.1 * trichomonas vaginalis 172.0 172.0 1 PMID:3879173 -2.6.1.102 * vibrio cholerae serotype o1 42.0 22.5 2 PMID:11479276 -2.6.1.11 * klebsiella aerogenes 34.6 34.6 1 PMID:24039 -2.6.1.116 * pseudomonas jessenii 0.9 0.9 1 PMID:31162815 -2.6.1.120 * lachancea kluyveri 4.5 4.5 1 PMID:17355287 -2.6.1.120 * rattus norvegicus 1.57 0.989 2 PMID:3085724;PMID:6816789 -2.6.1.13 * bacillus sp. (in: firmicutes) 76.0 76.0 1 PMID:8537297 -2.6.1.13 * bos taurus 0.0039 0.00375 2 PMID:28272331 -2.6.1.13 * homo sapiens 33.0 0.00275 15 PMID:10807973;PMID:23105736;PMID:23747282;PMID:28272331;PMID:28345116;PMID:6819292;PMID:9727717 -2.6.1.13 * lathyrus oleraceus 3.624 3.624 1 PMID:28272331 -2.6.1.13 * lysinibacillus sphaericus 53.6 27.135 2 PMID:488351;PMID:7287630 -2.6.1.13 * manduca sexta 1.6 1.6 1 PMID:2295622 -2.6.1.13 * mus musculus 19.08 0.00018 3 PMID:28272331;PMID:9873834 -2.6.1.13 * oryctolagus cuniculus 0.0112 0.004 5 PMID:28272331 -2.6.1.13 * plasmodium falciparum 20.9 1.95 4 PMID:20673832 -2.6.1.13 * raphanus sativus 1.38 1.38 1 * -2.6.1.13 * rattus norvegicus 16.0 0.0225 19 PMID:10807973;PMID:14284729;PMID:23105849;PMID:28272331;PMID:3178724;PMID:6819292 -2.6.1.13 * salmo trutta 5.5e-07 5.5e-07 1 PMID:28272331 -2.6.1.13 * staphylococcus aureus 0.55 0.55 1 PMID:7287630 -2.6.1.13 * sus scrofa 0.0026 0.0026 1 PMID:11420426 -2.6.1.13 * toxoplasma gondii 2.6 2.6 1 PMID:28126740 -2.6.1.14 * mus musculus 5.08 5.08 1 PMID:3099645 -2.6.1.14 * rattus norvegicus 0.25 0.25 1 PMID:14957 -2.6.1.15 * rattus norvegicus 5.0 0.29000000000000004 4 PMID:3003500;PMID:4797019;PMID:4822504 -2.6.1.15 * rhizobium etli 0.013 0.013 1 * -2.6.1.16 * bacillus thuringiensis 3.6 3.6 1 PMID:6426523 -2.6.1.16 * blastocladiella emersonii 3.5 3.5 1 PMID:4692652 -2.6.1.16 * candida albicans 12.0 0.89 3 PMID:16169745;PMID:17309446 -2.6.1.16 * escherichia coli 7.63 2.195 4 PMID:16871653;PMID:3297136;PMID:6426523;PMID:8621700 -2.6.1.16 * gallus gallus 4.66 2.33235 2 * -2.6.1.16 * homo sapiens 34.8 34.8 1 PMID:1247594 -2.6.1.16 * paenarthrobacter aurescens 8.0 8.0 1 PMID:6426523 -2.6.1.16 * pseudomonas aeruginosa 1.2 1.2 1 PMID:6426523 -2.6.1.16 * rattus norvegicus 0.866 0.16 3 PMID:10898949;PMID:13829889;PMID:3003497 -2.6.1.16 * saccharomyces cerevisiae 4.93 2.468915 2 PMID:24930098 -2.6.1.16 * vigna radiata var. radiata 0.0144 0.0144 1 PMID:16658095 -2.6.1.17 * escherichia coli 5.33 5.33 1 PMID:13734750 -2.6.1.18 * achromobacter denitrificans 77.2 77.2 1 PMID:15066855 -2.6.1.18 * pseudomonas fluorescens 56.6 56.6 1 PMID:13712439 -2.6.1.18 * sphaerobacter thermophilus 3.3 3.3 1 PMID:27178795 -2.6.1.18 * variovorax paradoxus 26.0 26.0 1 PMID:29120530 -2.6.1.18 * vibrio fluvialis 25.0 25.0 1 * -2.6.1.19 * bos taurus 18.0 18.0 1 PMID:11561735 -2.6.1.19 * candida guilliermondii var. membranaefaciens 52.33 52.33 1 PMID:3699025 -2.6.1.19 * corynebacterium glutamicum 1.34 0.685 2 * -2.6.1.19 * homo sapiens 17.5 4.9 3 PMID:15528998;PMID:15650327;PMID:4154214 -2.6.1.19 * lachancea kluyveri 12.8 2.56 8 PMID:17355287 -2.6.1.19 * mus musculus 5.0 5.0 1 PMID:4719123 -2.6.1.19 * oryza sativa 1736.0 1736.0 1 * -2.6.1.19 * ovis aries 4.1 4.1 1 PMID:3355498 -2.6.1.19 * pseudomonas aeruginosa 5.85 5.85 1 PMID:825509 -2.6.1.19 * pseudomonas fluorescens 3.4 3.4 1 PMID:13654294 -2.6.1.19 * pseudomonas sp. 46.8 46.8 1 PMID:7362249 -2.6.1.19 * rattus norvegicus 600.0 90.0 6 PMID:10447691;PMID:1164912;PMID:623769 -2.6.1.19 * saccharomyces cerevisiae 3.6 1.875 2 PMID:17355287 -2.6.1.19 * schistocerca gregaria 4.36 4.36 1 PMID:3355498 -2.6.1.19 * schizosaccharomyces pombe 3.67 1.905 2 PMID:17355287 -2.6.1.19 * solanum lycopersicum 5.79 0.1925 6 PMID:19470656 -2.6.1.19 * streptomyces griseus 9.64 9.64 1 PMID:3917915 -2.6.1.19 * sus scrofa 18.2 1.8 3 PMID:17988152;PMID:23842;PMID:8385114 -2.6.1.2 * candida maltosa 594.0 375.0 2 PMID:7764540 -2.6.1.2 * canis lupus familiaris 229.8 114.96000000000001 2 PMID:16495081 -2.6.1.2 * chlamydomonas reinhardtii 18.66 18.66 1 PMID:1662617 -2.6.1.2 * clarias batrachus 89.5 89.5 1 PMID:14990216 -2.6.1.2 * homo sapiens 60.2 3.25 4 PMID:18508279;PMID:19545238 -2.6.1.2 * hordeum vulgare 2231.0 2231.0 1 PMID:16669068 -2.6.1.2 * labeo rohita 50.0 50.0 1 PMID:14990216 -2.6.1.2 * lachancea kluyveri 4.5 2.56 4 PMID:17355287 -2.6.1.2 * leptosphaeria michotii 360.0 360.0 1 * -2.6.1.2 * oryctolagus cuniculus 1.58 1.58 1 PMID:6816789 -2.6.1.2 * panicum miliaceum 387.9 387.9 1 PMID:1898070 -2.6.1.2 * pyrococcus furiosus 243.0 200.5 2 PMID:10762259 -2.6.1.2 * rattus norvegicus 480.0 43.3 3 PMID:15663181;PMID:590935 -2.6.1.2 * sagmatias obliquidens 35.5 35.5 1 PMID:4462740 -2.6.1.2 * solanum lycopersicum 120.0 120.0 1 PMID:4847569 -2.6.1.2 * sus scrofa 213.0 108.275 2 PMID:454616 -2.6.1.2 * zea mays 127.5 64.445 2 PMID:10547044 -2.6.1.21 * bacillus sp. (in: firmicutes) 0.61 0.61 1 PMID:31990173 -2.6.1.21 * bacillus subtilis 90.0 90.0 1 PMID:4953710 -2.6.1.21 * lathyrus oleraceus 0.088 0.088 1 PMID:4710577 -2.6.1.22 * rattus norvegicus 0.133 0.096 3 PMID:10989446 -2.6.1.22 * sus scrofa 0.185 0.185 1 PMID:5641913 -2.6.1.23 * rattus norvegicus 0.49 0.49 1 PMID:13948827 -2.6.1.24 * rattus norvegicus 0.53 0.53 1 PMID:4381052 -2.6.1.26 * oryctolagus cuniculus 15.0 7.5065 2 PMID:4686924 -2.6.1.27 * clostridium sporogenes 23.6 23.6 1 PMID:5697992 -2.6.1.27 * sus scrofa 7.04 7.04 1 PMID:5722279 -2.6.1.28 * pseudomonas sp. 76.0 76.0 1 * -2.6.1.29 * amycolatopsis lactamdurans 0.00064 0.00064 1 PMID:2492500 -2.6.1.29 * escherichia coli 1.63 1.63 1 PMID:14154456 -2.6.1.29 * streptomyces clavuligerus 0.00238 0.00238 1 PMID:2492500 -2.6.1.29 * streptomyces glaucescens 0.00116 0.00116 1 PMID:2492500 -2.6.1.29 * streptomyces griseus 0.00192 0.00192 1 PMID:2492500 -2.6.1.29 * streptomyces lividans 0.0021 0.0021 1 PMID:2492500 -2.6.1.29 * streptomyces parvulus 0.00064 0.00064 1 PMID:2492500 -2.6.1.29 * streptomyces phaeochromogenes 0.00248 0.00248 1 PMID:2492500 -2.6.1.29 * streptomyces rimosus 0.0011 0.0011 1 PMID:2492500 -2.6.1.29 * streptomyces venezuelae 0.00156 0.00156 1 PMID:2492500 -2.6.1.29 * streptomyces viridochromogenes 0.00167 0.00167 1 PMID:2492500 -2.6.1.3 * rattus norvegicus 2.085 2.085 1 PMID:20209 -2.6.1.30 * brucella anthropi 0.00631 0.00631 1 * -2.6.1.30 * pseudomonas sp. 7.3 7.3 1 PMID:14004227 -2.6.1.31 * escherichia coli 0.076 0.076 1 PMID:14004226 -2.6.1.31 * oryctolagus cuniculus 0.081 0.081 1 PMID:14004226 -2.6.1.31 * rattus norvegicus 0.066 0.066 1 PMID:14189882 -2.6.1.33 * escherichia coli 0.047 0.047 1 PMID:5332731 -2.6.1.35 * paracoccus denitrificans 0.043 0.043 1 * -2.6.1.35 * rhodobacter capsulatus 0.23 0.23 1 * -2.6.1.36 * [flavobacterium] lutescens 18.67 18.67 1 PMID:5722276 -2.6.1.36 * saccharopolyspora erythraea 0.17 0.17 1 PMID:26827769 -2.6.1.36 * streptomyces clavuligerus 1.78 0.95 2 PMID:17288446 -2.6.1.37 * pseudomonas aeruginosa 16.64 16.64 1 PMID:6406228 -2.6.1.38 * comamonas testosteroni 17.8 17.8 1 PMID:241324 -2.6.1.38 * streptomyces tendae 0.866 0.002 5 * -2.6.1.39 * bos taurus 0.53 0.53 1 PMID:2803240 -2.6.1.39 * homo sapiens 10.68 5.725 2 PMID:8087205 -2.6.1.39 * rattus norvegicus 26.1 2.65 5 PMID:3003514;PMID:6830814;PMID:7493966;PMID:873907 -2.6.1.39 * thermus thermophilus 6788.0 661.0 7 PMID:15256574 -2.6.1.4 * homo sapiens 87.0 2.1 5 PMID:19545238 -2.6.1.4 * rattus norvegicus 0.13 0.13 1 PMID:14169146 -2.6.1.4 * rhodopseudomonas palustris 3.25 3.25 1 PMID:12784618 -2.6.1.4 * spinacia oleracea 2.4 2.4 1 PMID:5052220 -2.6.1.40 * rattus norvegicus 11.3 6.220000000000001 2 PMID:10989446;PMID:2306461 -2.6.1.40 * sus scrofa 0.093 0.093 1 PMID:5773299 -2.6.1.42 * bacillus thuringiensis 0.0015 0.00022 3 PMID:29310855 -2.6.1.42 * brevibacillus brevis 41.8 27.799999999999997 2 PMID:29523060;PMID:7542327 -2.6.1.42 * canis lupus familiaris 74.0 74.0 1 PMID:2853816 -2.6.1.42 * deinococcus radiodurans 180.0 180.0 1 PMID:22984263 -2.6.1.42 * escherichia coli 27.3 23.9 4 PMID:29523060;PMID:3069843;PMID:378964 -2.6.1.42 * evansella cellulosilytica 0.0014 0.00042 3 PMID:29310855 -2.6.1.42 * gluconobacter oxydans 49.7 42.8 3 PMID:29523060 -2.6.1.42 * haliangium ochraceum 0.23 0.1275 8 PMID:30902765 -2.6.1.42 * helicobacter pylori 27.3 27.3 1 PMID:29523060 -2.6.1.42 * homo sapiens 125.0 105.0 2 PMID:10989444 -2.6.1.42 * hordeum vulgare 0.02 0.02 1 * -2.6.1.42 * lacticaseibacillus paracasei 11.1 11.1 2 PMID:14962140;PMID:29523060 -2.6.1.42 * lactococcus lactis 94.0 27.0 7 PMID:10653720;PMID:10831406;PMID:29523060 -2.6.1.42 * methanococcus aeolicus 1.5 0.753 2 PMID:2002010;PMID:29523060 -2.6.1.42 * methanococcus vannielii 3.0 0.035 3 PMID:29453991 -2.6.1.42 * mycobacterium tuberculosis 14.35 5.7 11 PMID:15471546;PMID:29523060 -2.6.1.42 * neurospora crassa 48.8 36.9 2 PMID:4268214 -2.6.1.42 * ovis aries 89.81 89.81 1 PMID:9914481 -2.6.1.42 * pseudomonas aeruginosa 90.0 90.0 1 PMID:29523060 -2.6.1.42 * pseudomonas sp. 2.5 2.5 1 PMID:29523060 -2.6.1.42 * rattus norvegicus 98.33 18.6 7 PMID:11733007;PMID:16194549;PMID:2156837;PMID:2853816;PMID:4968655;PMID:8381418 -2.6.1.42 * solanum lycopersicum 0.414 0.066 42 PMID:20435740;PMID:22226341 -2.6.1.42 * solanum pennellii 0.21 0.114 9 PMID:20435740;PMID:22226341 -2.6.1.42 * streptococcus mutans 104.6 77.03 5 PMID:22868765 -2.6.1.42 * sus scrofa 50.0 25.3 5 PMID:3241563;PMID:4979711;PMID:5922965;PMID:5922966;PMID:5943594 -2.6.1.42 * thermobaculum terrenum 42.0 0.012 3 PMID:29453991 -2.6.1.42 * thermococcus sp. cku-1 390.0 390.0 1 PMID:29523060 -2.6.1.42 * thermomicrobium roseum 37.0 0.15 3 PMID:29453991 -2.6.1.42 * thermoproteus uzoniensis 3.6 1.7 5 PMID:26872794;PMID:29523060 -2.6.1.42 * vulcanisaeta moutnovskia 4.37 1.76 22 PMID:27871372;PMID:29523060 -2.6.1.43 * bos taurus 0.753 0.4565 2 PMID:7287716;PMID:7364767 -2.6.1.43 * candida albicans 0.186 0.186 1 PMID:2154954 -2.6.1.43 * chlorella regularis 2.68 2.68 1 PMID:6486814 -2.6.1.43 * clostridium tetanomorphum 7.68 7.68 1 PMID:7061418 -2.6.1.43 * devosia riboflavina 1.02 1.02 1 PMID:3170516 -2.6.1.43 * mus musculus 0.0266 0.0266 1 PMID:2338161 -2.6.1.43 * rattus norvegicus 36.9 1.1105 4 PMID:2050138;PMID:3740843;PMID:3970940;PMID:7858420 -2.6.1.44 * canis lupus familiaris 91.0 2.93 3 PMID:629740 -2.6.1.44 * columba livia 10.6 10.6 1 PMID:1654790 -2.6.1.44 * felis catus 86.3 86.3 1 PMID:629740 -2.6.1.44 * homo sapiens 51.8 51.8 1 PMID:10960483 -2.6.1.44 * hydrogenobacter thermophilus 19.0 9.5355 2 PMID:20214682 -2.6.1.44 * mus musculus 23.2 23.2 1 PMID:629740 -2.6.1.44 * rattus norvegicus 160.0 13.01 4 PMID:629740;PMID:8797099 -2.6.1.44 * saccharomyces cerevisiae 180.2 170.1 2 PMID:16226833;PMID:3933486 -2.6.1.44 * thermococcus litoralis 29.0 29.0 1 PMID:15292154 -2.6.1.45 * cucumis sativus 34.4 34.4 1 PMID:16664409 -2.6.1.45 * hyphomicrobium methylovorum 72.0 70.75 2 PMID:2114288;PMID:8898880 -2.6.1.45 * lathyrus oleraceus 39.3 39.3 1 PMID:6407397 -2.6.1.45 * nicotiana tabacum 2.41 2.41 1 PMID:16664646 -2.6.1.45 * phaseolus vulgaris 6.97 6.97 1 PMID:4750762 -2.6.1.45 * secale cereale 53.2 53.2 1 PMID:2127336 -2.6.1.45 * spinacia oleracea 2.18 2.18 1 * -2.6.1.46 * halomonas elongata 0.171 0.171 1 * -2.6.1.46 * halorhodospira halochloris 0.054 0.054 1 * -2.6.1.46 * pseudomonas aeruginosa 2.21 2.21 1 PMID:15317763 -2.6.1.46 * xanthomonas sp. 0.00092 0.00092 1 PMID:4390206 -2.6.1.48 * anaerocolumna aminovalerica 15.5 15.5 1 PMID:3597403 -2.6.1.48 * candida tropicalis 0.026 0.026 1 * -2.6.1.48 * cyberlindnera jadinii 0.004 0.004 1 * -2.6.1.48 * debaryomyces hansenii 0.005 0.005 1 * -2.6.1.48 * meyerozyma guilliermondii 20.8 20.8 1 PMID:3778871 -2.6.1.48 * pseudomonas sp. 0.103 0.103 1 * -2.6.1.48 * rhodotorula glutinis 0.006 0.006 1 * -2.6.1.49 * cavia porcellus 0.0366 0.0366 1 PMID:5829872 -2.6.1.5 * rana temporaria 203.0 203.0 1 PMID:18134 -2.6.1.5 * rattus norvegicus 1200.0 416.0 7 PMID:15865;PMID:1682148;PMID:25067;PMID:40452;PMID:4396841;PMID:4403529;PMID:6104456 -2.6.1.5 * trypanosoma cruzi 6.06 6.06 1 PMID:8100416 -2.6.1.50 * micromonospora echinospora 0.24 0.24 1 PMID:2729940 -2.6.1.51 * canis lupus familiaris 31.38 13.12 3 PMID:851432 -2.6.1.51 * felis catus 16.63 15.315 2 PMID:851432 -2.6.1.51 * lathyrus oleraceus 13.1 8.7 10 * -2.6.1.51 * mus musculus 3.58 2.9050000000000002 2 PMID:851432 -2.6.1.51 * rattus norvegicus 25.7 4.35 6 PMID:12742;PMID:2691502;PMID:851432;PMID:8797099 -2.6.1.52 * alkalihalobacillus alcalophilus 42.0 42.0 1 * -2.6.1.52 * arabidopsis thaliana 21.22 5.195 4 PMID:16289358 -2.6.1.52 * bos taurus 1416.0 15.0 3 PMID:10637769;PMID:3579302 -2.6.1.52 * entamoeba histolytica 6.14 3.245 4 PMID:16289358 -2.6.1.52 * escherichia coli 42.3 3.6029999999999998 4 PMID:30925016 -2.6.1.52 * glycine max 7.0 7.0 1 * -2.6.1.52 * homo sapiens 12.0 12.0 1 PMID:19545238 -2.6.1.52 * niallia circulans 4.16 4.16 1 PMID:8695645 -2.6.1.52 * ovis aries 1.3 1.295 2 * -2.6.1.52 * tetradesmus obliquus 13.84 13.84 1 * -2.6.1.54 * clostridium butyricum 0.281 0.281 1 * -2.6.1.55 * achromobacter superficialis 5.19 2.8545000000000003 2 PMID:3003495;PMID:5012173 -2.6.1.57 * azospirillum brasilense 26.0 26.0 1 PMID:8868238 -2.6.1.57 * bacillus subtilis 950.0 522.5 2 PMID:11213 -2.6.1.57 * brevibacillus brevis 353.0 353.0 1 PMID:2440856 -2.6.1.57 * brevibacterium linens 6.5 3.38 4 * -2.6.1.57 * escherichia coli 170.0 120.1 2 PMID:3298975;PMID:8218300 -2.6.1.57 * flavobacterium sp. 1.59 1.04 2 PMID:6816714 -2.6.1.57 * pyrococcus furiosus 181.8 181.8 1 PMID:8125113 -2.6.1.57 * rattus norvegicus 15.4 15.4 1 PMID:3600371 -2.6.1.57 * thermococcus litoralis 424.0 267.0 2 PMID:8125113 -2.6.1.58 * mus musculus 13.8 13.8 1 PMID:14070 -2.6.1.59 * yersinia pseudotuberculosis 1.01 1.01 1 PMID:4928644 -2.6.1.6 * glycine max 8.7 8.05 2 * -2.6.1.6 * rattus norvegicus 1.033 1.033 1 PMID:4968655 -2.6.1.60 * macaca fuscata 0.105 0.105 1 PMID:25837 -2.6.1.60 * rattus norvegicus 12.9 6.5615000000000006 2 PMID:25837;PMID:3037260 -2.6.1.62 * corynebacterium glutamicum 19.9 9.965 2 PMID:108512 -2.6.1.62 * escherichia coli 98.0 98.0 1 PMID:1092681;PMID:374976 -2.6.1.64 * rattus norvegicus 6.48 2.9749999999999996 8 PMID:241631;PMID:3003501;PMID:4822504;PMID:727444;PMID:7476916;PMID:851419;PMID:8914928 -2.6.1.65 * pseudomonas sp. 0.3 0.3 1 PMID:44448 -2.6.1.67 * candida guilliermondii var. membranaefaciens 26.0 26.0 1 PMID:3622507 -2.6.1.7 * hansenula schneggii 16.9 8.535 2 PMID:3003516;PMID:3086302 -2.6.1.7 * homo sapiens 3.9 0.85 3 PMID:30873412 -2.6.1.7 * mus musculus 2.5 0.475 4 PMID:30873412 -2.6.1.7 * neurospora crassa 1.5 1.5 1 PMID:13357462;PMID:6830814 -2.6.1.7 * pyrococcus horikoshii 71.7 71.7 1 PMID:16511030 -2.6.1.7 * rattus norvegicus 7.8 1.56 9 PMID:1218085;PMID:13357462;PMID:1990007;PMID:3003514;PMID:3037259;PMID:6830814;PMID:7493966;PMID:7891071 -2.6.1.71 * meyerozyma guilliermondii 2.4 2.4 1 * -2.6.1.72 * pseudomonas putida 0.25 0.25 1 * -2.6.1.73 * brassica carinata 0.6 0.18 3 PMID:16667931 -2.6.1.73 * brassica napus 0.066 0.066 1 PMID:16667931 -2.6.1.75 * rattus norvegicus 0.423 0.297 3 PMID:2852419 -2.6.1.76 * halomonas elongata 12.0 12.0 1 PMID:9864317 -2.6.1.77 * bilophila wadsworthia 35.3 2.22 3 PMID:11082195 -2.6.1.77 * geobacillus thermodenitrificans subsp. thermodenitrificans 10.2 0.6950000000000001 10 PMID:26577674 -2.6.1.77 * pseudomonas aeruginosa 0.07 0.07 1 PMID:113035 -2.6.1.78 * anchusa officinalis 0.34 0.34 1 PMID:3196038 -2.6.1.78 * arabidopsis thaliana 28.2 28.2 1 PMID:20883697 -2.6.1.79 * arabidopsis thaliana 28.2 28.2 1 PMID:20883697 -2.6.1.79 * nicotiana sylvestris 8.3 0.125 9 PMID:3298985;PMID:3985619 -2.6.1.80 * hordeum vulgare 0.00088 0.0006900000000000001 2 * -2.6.1.81 * burkholderia cepacia 1.07 0.111 4 PMID:2865249;PMID:3129535 -2.6.1.81 * ectopseudomonas mendocina 0.37 0.07 3 PMID:3129535 -2.6.1.81 * oceanimonas doudoroffii 1.38 0.3 3 PMID:3129535 -2.6.1.81 * pseudomonas aeruginosa 1.06 0.2175 6 PMID:3129535 -2.6.1.81 * pseudomonas chlororaphis subsp. aureofaciens 0.9 0.11 3 PMID:3129535 -2.6.1.81 * pseudomonas fluorescens 0.77 0.083 3 PMID:3129535 -2.6.1.81 * pseudomonas formicans 1.12 0.58 3 PMID:3129535 -2.6.1.81 * pseudomonas putida 0.33 0.09 3 PMID:3129535 -2.6.1.81 * trinickia caryophylli 1.77 0.92 2 PMID:3129535 -2.6.1.81 * vogesella indigofera 2.33 0.77 4 PMID:3129535 -2.6.1.82 * escherichia coli 11.68 1.1035000000000001 4 PMID:12617754;PMID:3510672 -2.6.1.83 * chlamydomonas reinhardtii 12.0 6.1499999999999995 4 PMID:21206046;PMID:21633707 -2.6.1.83 * methanococcus maripaludis 0.39 0.39 1 PMID:20418392 -2.6.1.88 * klebsiella pneumoniae 0.7227 0.36292 2 PMID:10074065 -2.6.1.9 * bacillus subtilis 325.0 325.0 1 PMID:11213 -2.6.1.9 * corynebacterium glutamicum 2.8 0.45 8 PMID:18560156 -2.6.1.9 * neurospora sp. 60.3 60.3 1 PMID:13319331 -2.6.1.9 * nicotiana tabacum 0.01266 0.01266 1 PMID:11289510 -2.6.1.9 * salmonella enterica subsp. enterica serovar typhimurium 1885.0 52.8 3 PMID:4606869;PMID:4632247;PMID:5337155 -2.6.1.9 * zymomonas mobilis 18.24 11.6 5 PMID:7883715 -2.6.1.96 * arabidopsis thaliana 7.54 3.53 3 PMID:19264755 -2.6.1.96 * nicotiana tabacum 0.17 0.17 1 * -2.6.1.96 * oryza sativa 0.207 0.059 6 PMID:23421475 -2.6.1.96 * solanum lycopersicum 5.79 0.193 6 PMID:19470656 -2.7.1.1 * aeropyrum pernix 45.0 27.0 5 PMID:12374829 -2.7.1.1 * ascaris suum 6.0 6.0 1 * -2.7.1.1 * aspergillus niger 40.0 37.5 2 PMID:8031843 -2.7.1.1 * bos taurus 141.0 48.75 4 PMID:15724432 -2.7.1.1 * bubalus bubalis 13.06 13.06 1 PMID:9440232 -2.7.1.1 * candida maltosa 0.11 0.11 1 * -2.7.1.1 * canis lupus familiaris 8.4 8.4 1 PMID:15251466 -2.7.1.1 * catharanthus roseus 0.8 0.8 1 * -2.7.1.1 * drosophila melanogaster 137.0 98.5 2 PMID:6768723 -2.7.1.1 * eimeria tenella 2.0 2.0 1 PMID:2538747 -2.7.1.1 * helianthus annuus 19.3 19.3 1 PMID:20889232 -2.7.1.1 * homo sapiens 310.0 23.0 34 PMID:2043117;PMID:3341751;PMID:3756183;PMID:7061426;PMID:7730377;PMID:8679719;PMID:8717435;PMID:9879670 -2.7.1.1 * lysinibacillus sphaericus 1.95 0.941 3 PMID:17400775 -2.7.1.1 * moniliella megachiliensis 5.1 5.1 1 PMID:19804861 -2.7.1.1 * mus musculus 0.033 0.033 1 PMID:10488914 -2.7.1.1 * nicotiana tabacum 1.297 0.688 9 * -2.7.1.1 * ogataea angusta 268.8 182.25 2 PMID:14530868 -2.7.1.1 * oryctolagus cuniculus 165.0 150.3 6 PMID:7114848;PMID:7263629 -2.7.1.1 * rattus norvegicus 120.0 23.5 11 PMID:12513690;PMID:2802617;PMID:3593283;PMID:8690154;PMID:8804424 -2.7.1.1 * saccharomyces cerevisiae 120.0 120.0 1 PMID:12648923 -2.7.1.1 * schizosaccharomyces pombe 20.25 20.25 1 PMID:9666312 -2.7.1.1 * schwanniomyces occidentalis 0.197 0.174 2 PMID:7614556 -2.7.1.1 * solanum chacoense 5.3 5.3 1 PMID:16376570 -2.7.1.1 * solanum tuberosum 0.84 0.72 3 * -2.7.1.1 * sulfurisphaera tokodaii 26.0 26.0 1 PMID:16484213 -2.7.1.1 * sus scrofa 191.5 95.875 2 PMID:6639059 -2.7.1.1 * thermus caldophilus 196.0 196.0 1 PMID:16053915 -2.7.1.1 * thermus thermophilus 68.0 68.0 1 PMID:22591843 -2.7.1.1 * toxoplasma gondii 4.04 4.04 1 PMID:12076625 -2.7.1.1 * trypanosoma brucei 190.0 97.8 2 PMID:6489338 -2.7.1.1 * trypanosoma cruzi 19.44 14.355 2 PMID:12615324 -2.7.1.1 * xenopus laevis 112.0 112.0 1 PMID:26797504 -2.7.1.100 * arabidopsis thaliana 1.0 1.0 1 PMID:14684902 -2.7.1.100 * bacillus subtilis 1.5 1.5 1 PMID:14684902 -2.7.1.100 * klebsiella aerogenes 0.028 0.028 1 PMID:210167;PMID:6312270 -2.7.1.100 * lupinus luteus 0.1425 0.1425 1 PMID:16662931 -2.7.1.100 * solanum lycopersicum 0.0007 0.0007 1 PMID:16664444 -2.7.1.101 * mycobacterium butyricum 3.92 3.92 1 PMID:6269638 -2.7.1.102 * kluyvera cryocrescens 2.6 2.6 1 PMID:6249593 -2.7.1.105 * bos taurus 0.092 0.058499999999999996 4 PMID:1325453;PMID:2837472;PMID:2986553 -2.7.1.105 * columba sp. 0.11 0.11 1 PMID:3019688 -2.7.1.105 * homo sapiens 0.277 0.17099999999999999 4 PMID:15896703;PMID:18202014;PMID:8385136;PMID:9276680 -2.7.1.105 * rattus norvegicus 0.08 0.046 11 PMID:2542332;PMID:2986553;PMID:6323408;PMID:6458290;PMID:6458291;PMID:8385136 -2.7.1.105 * saccharomyces cerevisiae 1.3 0.925 2 PMID:2529854;PMID:2831055 -2.7.1.105 * sparus aurata 0.068 0.068 1 PMID:8109976 -2.7.1.105 * spinacia oleracea 0.718 0.36419999999999997 2 PMID:11856361;PMID:3023092 -2.7.1.105 * trypanosoma brucei 0.011 0.011 1 PMID:16008555 -2.7.1.106 * bos taurus 0.136 0.07025 2 PMID:670163 -2.7.1.107 * bacillus subtilis 89.0 46.9 2 PMID:17535816 -2.7.1.107 * caenorhabditis elegans 7.5 0.0019 5 PMID:15563467 -2.7.1.107 * catharanthus roseus 0.231 0.231 1 PMID:16666963 -2.7.1.107 * escherichia coli 102.0 11.5 3 PMID:12974643;PMID:2828054;PMID:2984194 -2.7.1.107 * homo sapiens 6.913 5.7465 4 PMID:2172248;PMID:2175712 -2.7.1.107 * mammalia 0.0002 0.0002 1 PMID:15544348 -2.7.1.107 * rattus norvegicus 11.5 8.3435 2 PMID:2153114 -2.7.1.107 * staphylococcus aureus 0.0249 0.0249 1 PMID:19112175 -2.7.1.107 * sus scrofa 15.0 8.0 3 PMID:1323029;PMID:6296111 -2.7.1.108 * rattus norvegicus 3.8 0.365 4 PMID:6293584 -2.7.1.11 * amycolatopsis methanolica 160.0 160.0 1 PMID:11717283;PMID:8136379 -2.7.1.11 * apis mellifera 130.0 130.0 1 PMID:2947573 -2.7.1.11 * ascaris suum 49.6 49.6 1 PMID:6460771 -2.7.1.11 * aspergillus niger 6.1 6.1 1 PMID:6223622 -2.7.1.11 * bacillus licheniformis 9.6 9.6 1 PMID:6218376 -2.7.1.11 * bombus atratus 123.0 123.0 1 PMID:2972719 -2.7.1.11 * bos taurus 93.0 80.25 2 PMID:1386580 -2.7.1.11 * canis lupus familiaris 4.6 0.117 7 PMID:31474665 -2.7.1.11 * clostridium pasteurianum 299.0 229.5 2 PMID:11717283;PMID:6218378;PMID:8136379 -2.7.1.11 * crassostrea virginica 146.7 146.7 1 PMID:6218372 -2.7.1.11 * cucumis sativus 27.0 21.0 2 * -2.7.1.11 * desulfurococcus amylolyticus 47.0 47.0 1 PMID:10795681 -2.7.1.11 * dunaliella marina 0.38 0.38 1 PMID:6462110 -2.7.1.11 * escherichia coli 263.0 197.5 4 PMID:2975159;PMID:6218375 -2.7.1.11 * gallus gallus 114.0 114.0 1 * -2.7.1.11 * geobacillus stearothermophilus 160.0 160.0 1 PMID:11717283;PMID:8136379 -2.7.1.11 * homo sapiens 99.5 94.75 2 * -2.7.1.11 * jaculus orientalis 76.0 70.5 2 PMID:1386797 -2.7.1.11 * klebsiella aerogenes 0.75 0.75 1 PMID:4242639 -2.7.1.11 * kluyveromyces lactis 101.0 101.0 1 PMID:9392075 -2.7.1.11 * komagataella pastoris 80.0 80.0 1 PMID:12125050;PMID:2148917 -2.7.1.11 * lactococcus lactis 161.0 161.0 1 PMID:6218377 -2.7.1.11 * lymantria dispar 96.0 96.0 1 * -2.7.1.11 * methanococcus maripaludis 0.0056 0.0056 1 PMID:8288525 -2.7.1.11 * monoraphidium minutum 122.0 122.0 1 PMID:16667595 -2.7.1.11 * mus musculus 150.0 143.0 2 PMID:10425167;PMID:6218371 -2.7.1.11 * musa acuminata 6.0 5.5 3 PMID:12721855 -2.7.1.11 * oceanimonas doudoroffii 2.5 2.5 1 PMID:242298 -2.7.1.11 * oncorhynchus mykiss 76.5 73.25 2 PMID:1477103;PMID:7627129 -2.7.1.11 * oryctolagus cuniculus 160.0 120.0 5 PMID:124386;PMID:8670219 -2.7.1.11 * ovis aries 160.0 160.0 1 * -2.7.1.11 * rana temporaria 80.0 80.0 1 PMID:12125050;PMID:2148917 -2.7.1.11 * rattus norvegicus 265.0 206.0 3 PMID:6220705;PMID:6223631 -2.7.1.11 * ricinus communis 48.0 34.5 2 PMID:16667239;PMID:6448583 -2.7.1.11 * saccharomyces cerevisiae 180.0 131.0 4 PMID:124388;PMID:6218374;PMID:6455071 -2.7.1.11 * schizosaccharomyces pombe 136.0 136.0 1 PMID:11015725 -2.7.1.11 * solanum lycopersicum 0.61 0.61 1 * -2.7.1.11 * solanum tuberosum 200.0 200.0 1 PMID:2975159 -2.7.1.11 * sparus aurata 2077.0 627.0 3 PMID:17229526;PMID:18483063 -2.7.1.11 * spinacia oleracea 600.0 310.25 2 PMID:16666957;PMID:17229148 -2.7.1.11 * streptococcus thermophilus 134.0 134.0 1 PMID:6457643 -2.7.1.11 * sus scrofa 128.0 114.0 2 PMID:124390 -2.7.1.11 * thermococcus kodakarensis 86.0 56.0 6 PMID:31337538 -2.7.1.11 * thermotoga maritima 62.0 62.0 1 PMID:11976749 -2.7.1.11 * thermus thermophilus 41.0 41.0 1 PMID:24328040 -2.7.1.11 * trachemys scripta 150.0 110.65 4 PMID:2137714;PMID:2976771 -2.7.1.11 * trypanosoma brucei 140.0 140.0 1 PMID:3158309 -2.7.1.113 * bacillus subtilis 8.1 2.3 5 PMID:11078735 -2.7.1.113 * homo sapiens 0.073 0.023 9 PMID:12535661;PMID:14565458;PMID:15748706;PMID:16436271;PMID:6295492;PMID:9463485 -2.7.1.113 * mus musculus 0.0007 0.0007 1 PMID:6260206 -2.7.1.113 * sus scrofa 3.38e-05 3.38e-05 1 PMID:231969 -2.7.1.114 * asplenium nidus 1.64 0.91 5 PMID:182131 -2.7.1.114 * epidendrum hybrid 0.05 0.05 1 PMID:182131 -2.7.1.114 * helianthus tuberosus 0.47 0.29 3 PMID:182131 -2.7.1.114 * herpes simplex virus 42.2 42.2 1 PMID:6267178 -2.7.1.114 * hordeum vulgare 0.06 0.055 2 PMID:182131 -2.7.1.114 * medicago sativa 0.002 0.002 1 PMID:182131 -2.7.1.118 * herpes simplex virus 0.0048 0.0048 1 PMID:6293576 -2.7.1.119 * streptomyces hygroscopicus 0.5 0.25015 2 PMID:2995542;PMID:3026811 -2.7.1.12 * corynebacterium glutamicum 1.429 0.388 3 PMID:19399347 -2.7.1.12 * escherichia coli 250.0 0.6547 7 PMID:8655507;PMID:8925917 -2.7.1.12 * sus scrofa 0.64 0.64 1 PMID:13416223 -2.7.1.127 * bos taurus 10.0 5.97 2 PMID:2549973;PMID:8948463 -2.7.1.127 * cavia porcellus 0.00029 0.00029 1 PMID:2821911 -2.7.1.127 * gallus gallus 16.0 15.0 4 PMID:15659385 -2.7.1.127 * homo sapiens 0.75 0.283 3 PMID:8390223;PMID:9155020 -2.7.1.127 * mus musculus 0.0026 0.0015199999999999999 2 PMID:15381088 -2.7.1.127 * rattus norvegicus 60.0 3.5 17 PMID:10329669;PMID:15659385;PMID:1693074;PMID:2160980;PMID:2836386;PMID:3036860;PMID:3487541;PMID:9155020;PMID:9374536 -2.7.1.127 * sus scrofa 0.0244 0.0244 1 PMID:2839156 -2.7.1.13 * cupriavidus necator 8.7 8.7 1 PMID:31261738 -2.7.1.13 * klebsiella aerogenes 8.083 8.083 1 PMID:13894459 -2.7.1.136 * escherichia coli 0.21 0.08 6 PMID:15033229 -2.7.1.137 * bos taurus 0.25 0.05 3 PMID:1850737;PMID:2167854 -2.7.1.137 * homo sapiens 0.0086 0.00225 4 PMID:15135396 -2.7.1.137 * rattus norvegicus 0.214 0.124 3 PMID:2174051 -2.7.1.138 * homo sapiens 0.92 0.460625 2 PMID:12927832;PMID:16269826 -2.7.1.138 * mus musculus 1.41e-06 3.8e-08 5 PMID:18292572 -2.7.1.14 * mus musculus 128.0 128.0 1 PMID:18775706 -2.7.1.144 * staphylococcus aureus 17.5 8.822 2 PMID:6251066 -2.7.1.144 * staphylococcus epidermidis 0.303 0.303 1 * -2.7.1.144 * staphylococcus hominis 0.212 0.212 1 * -2.7.1.144 * streptococcus mutans 0.477 0.158 11 PMID:230175 -2.7.1.145 * drosophila melanogaster 51.6 26.6 8 PMID:10692477;PMID:14565458;PMID:9461577;PMID:9598112 -2.7.1.146 * archaeoglobus fulgidus 392.0 6.055 4 PMID:11702074;PMID:15064987 -2.7.1.146 * methanocaldococcus jannaschii 8.2 8.2 2 PMID:11717273 -2.7.1.146 * pyrococcus furiosus 88.0 88.0 1 PMID:10409652 -2.7.1.146 * thermococcus kodakarensis 5090.0 66.0 13 PMID:31337538 -2.7.1.146 * thermococcus litoralis 157.0 157.0 1 PMID:12832801 -2.7.1.146 * thermococcus zilligii 190.0 190.0 1 PMID:10356998 -2.7.1.147 * archaeoglobus fulgidus 58.9 0.1 3 PMID:11702074;PMID:12802482 -2.7.1.147 * mus musculus 29.3 17.0 3 PMID:14975750 -2.7.1.147 * pyrococcus furiosus 307.0 177.5 4 PMID:11098152;PMID:11265478;PMID:11978175;PMID:8530474 -2.7.1.148 * aquifex aeolicus 1.5 1.5 1 PMID:18422643 -2.7.1.148 * solanum lycopersicum 33.0 33.0 1 PMID:10880567 -2.7.1.15 * bos taurus 23.2 23.2 1 PMID:13295274 -2.7.1.15 * lactiplantibacillus plantarum 89.0 83.0 2 PMID:13641245 -2.7.1.15 * salmonella enterica subsp. enterica serovar typhimurium 70.0 70.0 1 PMID:4376665 -2.7.1.151 * gallus gallus 0.0085 0.0085 1 PMID:6277767 -2.7.1.151 * homo sapiens 2.5 1.475 2 PMID:12027805;PMID:15659385 -2.7.1.151 * oryza sativa 3.08 1.82 6 * -2.7.1.151 * rattus norvegicus 0.5 0.5 1 PMID:16123124 -2.7.1.151 * saccharomyces cerevisiae 0.7 0.7 1 PMID:16123124 -2.7.1.156 * salmonella enterica subsp. enterica serovar typhimurium 0.001166 0.0006479999999999999 2 PMID:10869342;PMID:7559521 -2.7.1.157 * sus scrofa 1.43 1.43 1 PMID:8702831 -2.7.1.158 * homo sapiens 0.031 0.031 1 PMID:12084730 -2.7.1.158 * zea mays 0.625 0.625 1 PMID:17535825 -2.7.1.159 * arabidopsis thaliana 0.0044 0.0044 1 PMID:17698066 -2.7.1.159 * bos taurus 372.0 372.0 3 PMID:11533064;PMID:8662638 -2.7.1.159 * homo sapiens 500.0 500.0 1 PMID:11533064 -2.7.1.159 * rattus norvegicus 1780.0 1780.0 1 PMID:1331051 -2.7.1.16 * escherichia coli 833.0 833.0 1 PMID:5336963 -2.7.1.16 * lactiplantibacillus plantarum 11.6 11.6 1 PMID:13539035 -2.7.1.162 * bifidobacterium longum 1.49 0.1345 12 PMID:17720833 -2.7.1.163 * escherichia coli 36.3 21.0 5 PMID:15802221;PMID:18776672 -2.7.1.165 * hyphomicrobium methylovorum 181.0 181.0 1 PMID:1336459 -2.7.1.165 * hyphomicrobium sp. 0.05 0.05 1 PMID:4370494 -2.7.1.165 * picrophilus oshimae 358.0 179.035 2 PMID:16684110 -2.7.1.165 * pseudomonas sp. 0.05 0.05 1 PMID:4370494 -2.7.1.165 * thermoplasma acidophilum 118.0 118.0 3 * -2.7.1.17 * bos taurus 4.1 4.1 1 PMID:13549459 -2.7.1.17 * candida maltosa 0.07 0.07 1 PMID:16834601 -2.7.1.17 * escherichia coli 51.0 1.6 3 PMID:11168365;PMID:18586973 -2.7.1.17 * halorhabdus utahensis 93.3 93.3 1 PMID:32761262 -2.7.1.17 * heyndrickxia coagulans 1.62 1.62 1 PMID:27206341 -2.7.1.17 * klebsiella aerogenes 95.0 95.0 1 * -2.7.1.17 * klebsiella pneumoniae 2.1 2.1 1 PMID:1324398 -2.7.1.17 * kluyveromyces marxianus 46.0 34.75 2 PMID:21451977 -2.7.1.17 * mucor circinelloides 10.8 10.8 1 PMID:25163569 -2.7.1.17 * saccharococcus caldoxylosilyticus 185.0 122.5 2 * -2.7.1.17 * scheffersomyces stipitis 21.4 21.4 1 * -2.7.1.171 * homo sapiens 2.08 2.08 1 PMID:11522682 -2.7.1.172 * spinacia oleracea 0.174 0.174 1 PMID:15705060 -2.7.1.173 * vigna radiata var. radiata 9e-06 9e-06 1 PMID:18042392 -2.7.1.174 * saccharomyces cerevisiae 130.0 65.009 2 PMID:18458076 -2.7.1.175 * streptomyces coelicolor 144.8 144.8 1 PMID:15378530 -2.7.1.18 * roseateles saccharophilus 9.86 9.86 1 PMID:237174 -2.7.1.19 * alexandrium minutum 0.331 0.331 1 PMID:19926682 -2.7.1.19 * anabaena cylindrica 15.17 8.56 2 * -2.7.1.19 * asterionella formosa 0.031 0.0245 2 PMID:19926682 -2.7.1.19 * aulacoseira granulata 0.069 0.069 1 PMID:19926682 -2.7.1.19 * bumilleriopsis peterseniana 0.074 0.074 1 PMID:19926682 -2.7.1.19 * chlamydomonas reinhardtii 410.0 3.895 3 PMID:16667433;PMID:19926682 -2.7.1.19 * chlorogloeopsis fritschii 14.24 14.24 1 * -2.7.1.19 * cupriavidus necator 88.9 48.245000000000005 2 PMID:4369092;PMID:6260209 -2.7.1.19 * cyanophora paradoxa 0.62 0.62 1 PMID:19926682 -2.7.1.19 * dinobryon sociale 0.075 0.075 1 PMID:19926682 -2.7.1.19 * emiliania huxleyi 0.029 0.029 1 PMID:19926682 -2.7.1.19 * euglena gracilis 0.306 0.306 1 PMID:19926682 -2.7.1.19 * fistulifera pelliculosa 0.176 0.176 1 PMID:19926682 -2.7.1.19 * halothiobacillus neapolitanus 50.0 50.0 1 PMID:5079073 -2.7.1.19 * hemiselmis rufescens 0.068 0.068 1 PMID:19926682 -2.7.1.19 * heterosigma akashiwo 217.8 217.8 1 PMID:9576802 -2.7.1.19 * mallomonas caudata 0.04 0.04 1 PMID:19926682 -2.7.1.19 * monoraphidium minutum 197.5 197.5 1 PMID:16668652 -2.7.1.19 * porphyridium purpureum 0.563 0.563 1 PMID:19926682 -2.7.1.19 * prochloron didemni 1.18 1.18 1 PMID:24264746 -2.7.1.19 * pseudocharaciopsis ovalis 0.097 0.097 1 PMID:19926682 -2.7.1.19 * rhodobacter capsulatus 48.7 48.7 1 PMID:6251028 -2.7.1.19 * rhodoblastus acidophilus 111.2 111.2 1 * -2.7.1.19 * spinacia oleracea 410.0 360.0 2 PMID:13295229;PMID:3004354 -2.7.1.19 * staurastrum cingulum 0.198 0.198 1 PMID:19926682 -2.7.1.19 * synechococcus sp. 230.0 151.3 2 PMID:12668773;PMID:8564307 -2.7.1.19 * tetradesmus obliquus 204.0 176.0 2 PMID:3009185 -2.7.1.19 * thalassiosira pseudonana 0.081 0.081 1 PMID:19926682 -2.7.1.19 * trieres chinensis 300.0 300.0 1 PMID:15734914 -2.7.1.19 * triticum aestivum 900.0 900.0 1 PMID:24241224 -2.7.1.197 * escherichia coli 26.67 13.3465 2 PMID:368051 -2.7.1.199 * staphylococcus carnosus 6.019 4.572 2 PMID:10537210 -2.7.1.2 * aeropyrum pernix 47.2 47.2 1 PMID:12761185 -2.7.1.2 * dictyostelium discoideum 0.51 0.51 1 PMID:4312464 -2.7.1.2 * escherichia coli 158.0 158.0 1 PMID:9023215 -2.7.1.2 * geobacillus stearothermophilus 334.0 319.0 2 PMID:3099754;PMID:4763322 -2.7.1.2 * lysinibacillus sphaericus c3-41 1.95 0.941 3 PMID:17400775 -2.7.1.2 * paracoccus versutus 74.9 74.9 1 * -2.7.1.2 * pseudomonas putida 0.0273 0.018750000000000003 4 PMID:17483213;PMID:17616587 -2.7.1.2 * streptococcus mutans 198.0 198.0 1 PMID:7150605 -2.7.1.2 * streptomyces coelicolor 1.67 1.67 1 PMID:15808940 -2.7.1.2 * streptomyces peucetius subsp. caesius 1.09 1.09 1 PMID:15808940 -2.7.1.2 * thermotoga maritima 370.0 268.0 2 PMID:12814622;PMID:14553940 -2.7.1.2 * zymomonas mobilis 240.0 240.0 1 PMID:2992451 -2.7.1.20 * cricetulus griseus 0.000888 0.000365 5 PMID:15106882 -2.7.1.20 * homo sapiens 6.3 1.6 9 PMID:17085766;PMID:17379518;PMID:227870;PMID:3036217;PMID:6246102;PMID:6268173 -2.7.1.20 * leishmania donovani 11.0 11.0 1 PMID:3032935 -2.7.1.20 * lupinus luteus 2.79 2.79 1 PMID:41481 -2.7.1.20 * mus musculus 0.305 0.305 1 PMID:6244278 -2.7.1.20 * mycobacterium tuberculosis 3.7 0.07200000000000001 10 PMID:14594827;PMID:17085766 -2.7.1.20 * oryctolagus cuniculus 1.75 0.905 2 PMID:218933;PMID:4290214 -2.7.1.20 * rattus norvegicus 18.0 7.8 3 PMID:2986372;PMID:6089741;PMID:6260151 -2.7.1.207 * staphylococcus aureus 0.0433 0.02205 2 PMID:9826184 -2.7.1.21 * badhamia polycephala 100.0 100.0 1 PMID:6841340 -2.7.1.21 * bos taurus 7.5 7.5 1 PMID:5127424 -2.7.1.21 * escherichia coli 720.0 361.7 2 PMID:14114853;PMID:357898 -2.7.1.21 * herpes simplex virus 0.46 0.1095 4 PMID:2845104;PMID:6311815;PMID:7706243;PMID:9866691 -2.7.1.21 * homo sapiens 325.0 0.109 4 PMID:1063125;PMID:3335503;PMID:6406493 -2.7.1.21 * human alphaherpesvirus 3 655.0 655.0 1 PMID:10733888 -2.7.1.21 * leishmania major 4.5 4.5 1 PMID:25978379 -2.7.1.21 * mus musculus 3.6 1.8265 2 PMID:4814718;PMID:8896760 -2.7.1.21 * rattus norvegicus 14.0 7.03 2 PMID:1911861;PMID:692391 -2.7.1.21 * tequatrovirus t4 11.0 11.0 1 PMID:338602 -2.7.1.215 * sinorhizobium meliloti 17.4 12.3 3 PMID:22609752 -2.7.1.22 * haemophilus influenzae 0.9 0.04 3 PMID:12446641 -2.7.1.22 * salmonella enterica 1.4 1.0 3 PMID:12446641;PMID:15805524 -2.7.1.22 * sus scrofa 4.25 4.25 1 PMID:14907738 -2.7.1.227 * aspergillus flavus 6.1 6.1 1 PMID:10681333 -2.7.1.227 * candida albicans 134.0 134.0 1 PMID:10681333 -2.7.1.227 * candida tropicalis 333.0 333.0 1 PMID:10681333 -2.7.1.227 * nakaseomyces glabratus 211.0 211.0 1 PMID:10681333 -2.7.1.229 * lactiplantibacillus plantarum 89.0 83.0 2 PMID:13641245 -2.7.1.229 * salmonella enterica subsp. enterica serovar typhimurium 70.0 70.0 1 PMID:4376665 -2.7.1.23 * arabidopsis thaliana 213.0 14.3 5 PMID:15247403 -2.7.1.23 * avena sativa 0.0009966 0.0009966 1 * -2.7.1.23 * azotobacter vinelandii 0.233 0.233 1 PMID:4290316 -2.7.1.23 * bacillus licheniformis 0.94 0.94 1 PMID:3017250 -2.7.1.23 * columba sp. 0.8 0.8 1 PMID:239 -2.7.1.23 * escherichia coli 12.86 12.45 3 PMID:11488932;PMID:15855156 -2.7.1.23 * homo sapiens 6.7 6.7 1 PMID:11594753 -2.7.1.23 * methanocaldococcus jannaschii 99.4 99.4 1 PMID:16192277 -2.7.1.23 * micrococcus flavus 24.3 20.935000000000002 4 PMID:12951510;PMID:15855156 -2.7.1.23 * mycobacterium tuberculosis 3.8 2.5 2 PMID:15182203 -2.7.1.23 * saccharomyces cerevisiae 3.2 3.2 1 PMID:221029 -2.7.1.23 * solanum pimpinellifolium 3.84 3.84 1 * -2.7.1.23 * sphingomonas sp. 0.281 0.281 1 PMID:15177293 -2.7.1.23 * strongylocentrotus purpuratus 0.222 0.1575 2 PMID:4355198;PMID:6246383 -2.7.1.239 * halopiger xanaduensis 30.1 30.1 1 PMID:36434094 -2.7.1.24 * corynebacterium ammoniagenes 22.0 6.5 3 PMID:11292795;PMID:8389542 -2.7.1.24 * entamoeba histolytica 2.54 2.335 2 PMID:30555442 -2.7.1.24 * rattus norvegicus 0.346 0.346 1 * -2.7.1.24 * sus scrofa 3.68 3.68 1 PMID:6312972 -2.7.1.25 * chlamydomonas reinhardtii 0.136 0.069 2 * -2.7.1.25 * escherichia coli 153.0 0.843 3 PMID:2549047;PMID:3019265 -2.7.1.25 * geobacillus stearothermophilus 1.7 1.7 1 * -2.7.1.25 * homo sapiens 0.12 0.12 1 PMID:15065880 -2.7.1.25 * mus musculus 0.00016 0.00016 1 PMID:10196147 -2.7.1.25 * penicillium chrysogenum 24.7 24.549999999999997 2 PMID:2981860;PMID:6321459 -2.7.1.25 * rattus norvegicus 52.5 52.5 1 PMID:3032273 -2.7.1.25 * saccharomyces cerevisiae 0.843 0.614 3 PMID:3019265 -2.7.1.26 * bacillus subtilis 0.0129 0.0129 1 PMID:226520 -2.7.1.26 * megasphaera elsdenii 0.0083 0.0083 1 PMID:195619 -2.7.1.26 * neurospora crassa 2.95 2.95 1 PMID:10650711 -2.7.1.26 * rattus norvegicus 0.79 0.165 3 PMID:2163401;PMID:6243635;PMID:9059983 -2.7.1.26 * vigna radiata var. radiata 0.322 0.322 1 PMID:6274324 -2.7.1.27 * acidipropionibacterium acidipropionici 0.51 0.51 1 PMID:13908588 -2.7.1.28 * rattus norvegicus 0.0034 0.0029 2 PMID:12049998 -2.7.1.29 * [candida] boidinii 20.33 20.33 1 PMID:2177824 -2.7.1.29 * [candida] methylica 37.65 37.65 1 PMID:2177825 -2.7.1.29 * schizosaccharomyces pombe 14.9 14.9 1 PMID:10091325 -2.7.1.3 * bos taurus 17.0 17.0 1 PMID:193556 -2.7.1.3 * homo sapiens 9.4 9.4 1 PMID:2996495 -2.7.1.3 * rattus norvegicus 0.02154 0.0006399999999999999 6 PMID:16465401 -2.7.1.30 * bos taurus 25.2 25.2 1 PMID:238627 -2.7.1.30 * candida mycoderma 101.0 101.0 1 * -2.7.1.30 * cellulomonas sp. 25.0 25.0 1 PMID:27112401;PMID:28284306 -2.7.1.30 * debaryomyces hansenii 177.0 177.0 1 * -2.7.1.30 * escherichia coli 100.0 70.6 2 PMID:5335908 -2.7.1.30 * geobacillus stearothermophilus 120.0 118.0 2 PMID:6312842 -2.7.1.30 * plasmodium falciparum 18.3 16.9 2 PMID:19040641 -2.7.1.30 * saccharomyces cerevisiae 0.13 0.092 2 * -2.7.1.30 * synechocystis sp. pcc 6803 2.4 2.4 1 PMID:30048929 -2.7.1.30 * thermococcus kodakarensis 2.0 2.0 1 PMID:22178023 -2.7.1.30 * trypanosoma brucei gambiense 32.0 16.2 2 PMID:23620597 -2.7.1.31 * arabidopsis thaliana 54.6 41.25 2 PMID:15980259 -2.7.1.31 * escherichia coli 210.0 210.0 1 PMID:166273;PMID:5325263 -2.7.1.31 * saccharomyces cerevisiae 21.3 21.3 1 PMID:15980259 -2.7.1.31 * zea mays 68.0 68.0 1 PMID:24226402 -2.7.1.32 * caenorhabditis elegans 43.0 22.7 2 PMID:12758145 -2.7.1.32 * cuscuta reflexa 17.9 17.9 1 PMID:5010855 -2.7.1.32 * homo sapiens 0.000484 0.000484 1 PMID:17465218 -2.7.1.32 * mus musculus 0.000139 0.000139 1 PMID:18029352 -2.7.1.32 * plasmodium falciparum 3d7 10.8 10.8 1 PMID:19845508 -2.7.1.32 * rattus norvegicus 143.0 1.5 7 PMID:1323026;PMID:1323027;PMID:1577786;PMID:2152925;PMID:2157491;PMID:2992596;PMID:4373031;PMID:6094572 -2.7.1.32 * trypanosoma brucei 10.67 10.67 1 PMID:18489261 -2.7.1.33 * corynebacterium ammoniagenes 0.034 0.034 1 * -2.7.1.33 * homo sapiens 0.0002421 0.0002421 1 PMID:17242360 -2.7.1.33 * picrophilus oshimae 0.36 0.36 1 PMID:19854913 -2.7.1.33 * rattus norvegicus 0.0041 0.00171 3 PMID:2999132;PMID:4337331;PMID:7084227 -2.7.1.33 * spinacia oleracea 0.152 0.152 1 PMID:8384834 -2.7.1.35 * bombyx mori 1.8 0.935 2 * -2.7.1.35 * bos taurus 2.105 1.05875 2 PMID:8384299 -2.7.1.35 * enterococcus faecalis 0.0036 0.0036 1 PMID:13773826 -2.7.1.35 * escherichia coli 2.7 1.3760000000000001 2 PMID:15249053 -2.7.1.35 * homo sapiens 2.5 2.4850000000000003 2 PMID:10987144;PMID:15249053 -2.7.1.35 * lacticaseibacillus casei 0.00135 0.00135 1 PMID:13773826 -2.7.1.35 * leishmania donovani 1847.0 1847.0 1 PMID:30031075 -2.7.1.35 * plasmodium falciparum 0.112 0.05 9 PMID:15590634;PMID:19197387 -2.7.1.35 * rattus norvegicus 1.42 0.64125 4 PMID:13773826;PMID:2988502 -2.7.1.35 * sus scrofa 0.1447 0.108 2 PMID:11983425;PMID:221500 -2.7.1.35 * trypanosoma brucei 0.52 0.52 1 PMID:9274862 -2.7.1.36 * catharanthus roseus 10.6 10.6 1 PMID:10860546 -2.7.1.36 * cucumis melo 0.014 0.014 1 PMID:4343214 -2.7.1.36 * enterococcus faecalis 24.0 24.0 1 PMID:14767074 -2.7.1.36 * hevea brasiliensis 1.55 0.985 2 PMID:4343214;PMID:5862423 -2.7.1.36 * homo sapiens 37.0 37.0 1 PMID:9325256 -2.7.1.36 * methanocaldococcus jannaschii 387.0 387.0 1 PMID:10497066 -2.7.1.36 * oryctolagus cuniculus 0.11 0.11 1 * -2.7.1.36 * phaseolus vulgaris 0.084 0.084 1 PMID:4343214 -2.7.1.36 * rattus norvegicus 32.7 32.7 3 PMID:12509999;PMID:14680942;PMID:2153681 -2.7.1.36 * saccharomyces cerevisiae 0.77 0.77 1 PMID:4343214 -2.7.1.36 * staphylococcus aureus 12.4 12.4 1 PMID:14679225 -2.7.1.36 * sus scrofa 30.4 23.95 2 PMID:2991706;PMID:6311270 -2.7.1.36 * trypanosoma cruzi 72.8 72.8 1 PMID:27113535 -2.7.1.36 * trypanosoma evansi 11.0 11.0 1 PMID:30042928 -2.7.1.39 * [brevibacterium] flavum 0.293 0.293 1 PMID:5016260 -2.7.1.39 * arabidopsis thaliana 3.09 3.09 1 PMID:10562426 -2.7.1.39 * lathyrus oleraceus 0.024 0.024 1 * -2.7.1.39 * saccharomyces cerevisiae 3.1 3.1 1 PMID:2165904 -2.7.1.39 * triticum aestivum 8.34 8.34 1 * -2.7.1.4 * bifidobacterium longum 1.8 1.32 2 PMID:15375133 -2.7.1.4 * entamoeba histolytica 26.3 26.3 1 PMID:25700717 -2.7.1.4 * glycine max 11.2 11.2 1 PMID:16664355 -2.7.1.4 * hordeum vulgare 60.3 56.05 2 * -2.7.1.4 * lactococcus lactis 112.0 112.0 1 PMID:1658003 -2.7.1.4 * lathyrus oleraceus 2.7 1.397 2 PMID:16660504;PMID:6091556 -2.7.1.4 * leuconostoc mesenteroides 76.0 76.0 1 * -2.7.1.4 * nicotiana tabacum 0.00746 0.00746 1 * -2.7.1.4 * rhizobium leguminosarum 10.8 10.8 1 PMID:8932706 -2.7.1.4 * saccharum sp. 44.05 31.439999999999998 2 * -2.7.1.4 * solanum lycopersicum 25.0 24.2 3 PMID:9325137 -2.7.1.4 * solanum tuberosum 20.2 11.7 4 PMID:16652943 -2.7.1.4 * streptomyces violaceoruber 40.0 40.0 1 PMID:164228;PMID:4635822 -2.7.1.4 * thermococcus litoralis 920.0 825.0 2 PMID:15138858 -2.7.1.4 * zea mays 835.0 835.0 1 * -2.7.1.4 * zymomonas mobilis 250.0 250.0 1 PMID:8776754 -2.7.1.40 * archaeoglobus fulgidus 1000.0 0.13 3 PMID:11702074;PMID:12654928 -2.7.1.40 * bacillus licheniformis 210.0 192.5 2 PMID:7549104 -2.7.1.40 * bos taurus 233.0 233.0 1 * -2.7.1.40 * brassica juncea 690.7 690.7 1 * -2.7.1.40 * brassica napus 51.0 51.0 1 PMID:10880971 -2.7.1.40 * busycotypus canaliculatum 368.0 368.0 1 PMID:6468395 -2.7.1.40 * corynebacterium glutamicum 1.64 1.64 1 PMID:27852252 -2.7.1.40 * geobacillus stearothermophilus 333.0 333.0 1 PMID:3711058 -2.7.1.40 * homo sapiens 420.0 290.0 4 PMID:16147999 -2.7.1.40 * leishmania donovani 178.1 178.1 1 PMID:18725273 -2.7.1.40 * methanococcus maripaludis 0.004 0.004 1 PMID:8288525 -2.7.1.40 * moniliella megachiliensis 0.05 0.05 1 PMID:19804861 -2.7.1.40 * monoraphidium minutum 218.0 218.0 1 * -2.7.1.40 * mucor racemosus 1685.0 1685.0 1 PMID:3611022 -2.7.1.40 * mus musculus 397.5 388.75 2 PMID:6784752 -2.7.1.40 * musa cavendishii 59.0 59.0 1 * -2.7.1.40 * mycobacterium tuberculosis 5.31 5.31 1 PMID:30531037 -2.7.1.40 * mycolicibacterium smegmatis 220.0 220.0 1 PMID:6614924 -2.7.1.40 * rattus norvegicus 1341.0 593.0 7 PMID:3970531;PMID:7115773 -2.7.1.40 * ricinus communis 203.0 62.05 4 PMID:16049677;PMID:16666032;PMID:8806784 -2.7.1.40 * saccharomyces cerevisiae 340.0 295.0 2 * -2.7.1.40 * solanum tuberosum 34.76 18.044999999999998 2 PMID:25573389 -2.7.1.40 * sporosarcina psychrophila 202.0 202.0 1 PMID:7549104 -2.7.1.40 * sus scrofa 191.0 116.7 3 PMID:17641091;PMID:7584599 -2.7.1.40 * tenebrio molitor 9.69 9.69 1 * -2.7.1.40 * thermoanaerobacterium saccharolyticum 0.001 0.001 1 PMID:23202749 -2.7.1.40 * thermoplasma acidophilum 201.0 201.0 1 * -2.7.1.40 * thermotoga maritima 320.0 320.0 1 PMID:12654928 -2.7.1.40 * trachemys scripta elegans 11.8 6.1450000000000005 2 PMID:29900073 -2.7.1.40 * urocitellus richardsonii 390.0 390.0 1 PMID:28918505 -2.7.1.40 * yersinia enterocolitica 108.0 96.5 2 PMID:23384479 -2.7.1.40 * zymomonas mobilis 280.0 280.0 1 PMID:3026343 -2.7.1.42 * escherichia coli 0.12 0.12 1 * -2.7.1.43 * arabidopsis thaliana 12.6 12.399999999999999 2 PMID:19951951 -2.7.1.43 * lilium longiflorum 17.9 17.9 3 PMID:192151;PMID:19951951 -2.7.1.45 * flavobacterium sp. umi-01 0.72 0.72 1 PMID:28216576 -2.7.1.46 * vigna radiata var. radiata 1.44 1.44 1 PMID:165743 -2.7.1.47 * klebsiella aerogenes 152.0 118.0 2 PMID:220218;PMID:6272710 -2.7.1.48 * entamoeba histolytica 0.17 0.17 1 PMID:19368743 -2.7.1.48 * escherichia coli 200.0 200.0 1 PMID:211379 -2.7.1.48 * geobacillus stearothermophilus 4.33 4.33 1 PMID:211377 -2.7.1.48 * mus musculus 283.0 80.5 3 PMID:166617;PMID:211380;PMID:2991280 -2.7.1.48 * rattus norvegicus 57.49 0.88 3 PMID:186262;PMID:211377;PMID:5782006 -2.7.1.49 * escherichia coli 4.344 2.3365 2 PMID:10075431;PMID:2540841 -2.7.1.49 * plasmodium falciparum 0.169 0.1385 2 PMID:16497163 -2.7.1.5 * arthrobacter pyridinolis 0.0047 0.0047 1 PMID:182906 -2.7.1.50 * escherichia coli 45.0 9.05 18 PMID:26634770 -2.7.1.50 * saccharomyces cerevisiae 0.53 0.53 1 PMID:8394314 -2.7.1.50 * staphylococcus aureus 7.42 7.3 3 PMID:26960569 -2.7.1.51 * citrobacter freundii 0.966 0.966 1 * -2.7.1.51 * escherichia coli 0.966 0.966 1 PMID:13905785 -2.7.1.52 * arabidopsis thaliana 82.9 82.9 1 PMID:18199744 -2.7.1.52 * canis lupus familiaris 0.0091 0.0091 1 PMID:20962 -2.7.1.52 * sus scrofa 1.273 0.6 3 PMID:40602;PMID:5646161;PMID:9488699 -2.7.1.53 * klebsiella aerogenes 340.6 340.6 1 PMID:13861293 -2.7.1.54 * acidipropionibacterium acidipropionici 37.0 37.0 1 PMID:13926593 -2.7.1.55 * klebsiella aerogenes 1.93 1.93 1 * -2.7.1.56 * [clostridium] symbiosum 6.9 6.9 1 PMID:4222878 -2.7.1.56 * klebsiella aerogenes 47.0 23.635 2 PMID:237207;PMID:4242639;PMID:4287754 -2.7.1.56 * oceanimonas doudoroffii 4.2 4.2 1 PMID:242298 -2.7.1.56 * pseudomonas putida 4.02 4.02 1 PMID:17464 -2.7.1.58 * escherichia coli 0.24 0.21 2 PMID:324806 -2.7.1.58 * haloferax volcanii 148.0 74.074 2 PMID:32055827 -2.7.1.58 * mycobacterium butyricum 0.086 0.086 1 PMID:7287628 -2.7.1.58 * salmonella enterica subsp. enterica serovar typhimurium 0.06 0.06 1 PMID:324806 -2.7.1.58 * stenotrophomonas maltophilia 0.04 0.04 1 PMID:11823194 -2.7.1.59 * candida albicans 9.5 9.5 1 PMID:6250622 -2.7.1.59 * capra hircus 0.009 0.009 1 PMID:4319609 -2.7.1.59 * escherichia coli 33.3 4.6 3 PMID:15489439 -2.7.1.59 * homo sapiens 1.28 0.640045 2 PMID:4365241;PMID:8982040 -2.7.1.59 * mus musculus 25.0 12.5685 2 PMID:10824116 -2.7.1.59 * plasmodium falciparum 0.00012 0.00012 1 PMID:8982040 -2.7.1.59 * rattus norvegicus 52.4 42.0 3 PMID:6248025;PMID:9523722 -2.7.1.59 * streptococcus pyogenes 250.0 250.0 1 * -2.7.1.59 * sus scrofa 90.0 45.0125 2 PMID:4319609 -2.7.1.6 * bifidobacterium bifidum 318.0 318.0 1 * -2.7.1.6 * bifidobacterium longum subsp. infantis 158.0 12.5 15 PMID:22633137 -2.7.1.6 * escherichia coli 23.5 23.5 1 PMID:15239057 -2.7.1.6 * homo sapiens 1.737 0.885 4 PMID:4052432;PMID:5028074 -2.7.1.6 * lactococcus lactis 11.5 5.965 2 PMID:23872454 -2.7.1.6 * rattus norvegicus 0.91 0.91 1 PMID:19433218 -2.7.1.6 * saccharomyces cerevisiae 38.3 38.3 1 PMID:14144 -2.7.1.6 * vicia faba 2.258 2.258 1 PMID:6617655 -2.7.1.6 * vigna radiata var. radiata 9.6 9.6 1 PMID:165743 -2.7.1.60 * homo sapiens 2.6 2.6 1 PMID:22343627 -2.7.1.60 * rattus norvegicus 10.9 3.38 6 PMID:10497249;PMID:13704957;PMID:15135418;PMID:5928201;PMID:9305887 -2.7.1.60 * salmonella enterica subsp. enterica serovar typhimurium 58.0 38.65 2 PMID:4889177 -2.7.1.61 * klebsiella aerogenes 1.3 1.3 1 PMID:6033450 -2.7.1.62 * escherichia coli 22.7 22.7 1 * -2.7.1.63 * arthrobacter sp. 220.0 165.0 2 PMID:12839753 -2.7.1.63 * mycobacterium tuberculosis 203.0 203.0 1 PMID:8617763 -2.7.1.63 * mycolicibacterium phlei 140.0 140.0 1 * -2.7.1.63 * propionibacterium freudenreichii subsp. shermanii 130.0 72.65 2 PMID:3007458 -2.7.1.63 * thermobifida fusca 285.3 174.95 2 PMID:21766194;PMID:29884753 -2.7.1.64 * thermococcus kodakarensis 44.27 0.5 11 PMID:23737529 -2.7.1.66 * staphylococcus aureus 0.54 0.54 1 PMID:5057461 -2.7.1.66 * streptococcus mutans 8.8 4.15 10 PMID:24990652 -2.7.1.67 * bos taurus 2.7 0.027 3 PMID:2155029;PMID:2837470;PMID:3036072 -2.7.1.67 * daucus carota 0.0075 0.0075 1 PMID:12228376 -2.7.1.67 * dunaliella parva 0.077 0.077 1 * -2.7.1.67 * homo sapiens 1.18 0.8155 4 PMID:11277933;PMID:1652438;PMID:1657176;PMID:2851325 -2.7.1.67 * ovis aries 1.149 1.149 1 PMID:1655428 -2.7.1.67 * rattus norvegicus 0.143 0.10146999999999999 2 PMID:10549154;PMID:2846568 -2.7.1.67 * saccharomyces cerevisiae 5.08 4.525 4 PMID:1322897;PMID:1323031;PMID:1331109;PMID:6311802 -2.7.1.67 * sus scrofa 8.824 8.824 1 PMID:2830904 -2.7.1.68 * bos taurus 0.171 0.128 2 PMID:1323033;PMID:2152796 -2.7.1.68 * homo sapiens 0.117 0.023 3 PMID:1323032;PMID:2538472 -2.7.1.68 * ovis aries 1.75 1.75 1 PMID:8744418 -2.7.1.68 * rattus norvegicus 1.021 1.0 3 PMID:2157497;PMID:3026313;PMID:6093768 -2.7.1.68 * schizosaccharomyces pombe 1.704 1.704 1 PMID:9873063 -2.7.1.7 * arthrobacter sp. 220.0 55.0385 4 PMID:12839753 -2.7.1.7 * escherichia coli 1.5 1.5 1 PMID:4557975 -2.7.1.7 * leuconostoc mesenteroides 76.0 76.0 1 * -2.7.1.7 * streptomyces violaceoruber 7.5 7.5 1 PMID:4635821 -2.7.1.71 * escherichia coli 410.0 100.0 3 PMID:3001029;PMID:3037263 -2.7.1.71 * mycobacterium tuberculosis 101.9 101.9 1 PMID:22876783 -2.7.1.71 * sorghum bicolor 0.05718 0.05718 1 PMID:16660971 -2.7.1.71 * spinacia oleracea 8.39 8.39 1 PMID:16667533 -2.7.1.72 * streptomyces griseus 11.35 11.35 1 PMID:6313852 -2.7.1.73 * escherichia coli 3.7 3.7 1 PMID:7665468 -2.7.1.73 * halobacterium salinarum 60.0 55.0 2 PMID:9457844 -2.7.1.73 * haloferax volcanii 120.0 120.0 2 PMID:9457844 -2.7.1.74 * bos taurus 0.0206 0.00916 4 PMID:211383;PMID:5043847;PMID:5442271;PMID:5684726 -2.7.1.74 * homo sapiens 1648.0 5.25 14 PMID:15748706;PMID:18361501;PMID:2013338;PMID:2539852;PMID:2542307;PMID:2844225;PMID:8399394 -2.7.1.74 * mus musculus 0.0846 0.0048 3 PMID:5687717;PMID:999281 -2.7.1.76 * bacillus subtilis 2.3 2.3 1 PMID:11078735 -2.7.1.76 * bos taurus 0.073 0.073 1 PMID:5554289 -2.7.1.76 * homo sapiens 0.54 0.2285 4 PMID:12535661;PMID:14565458 -2.7.1.76 * rattus norvegicus 0.06 0.06 1 PMID:4371811 -2.7.1.76 * solanum tuberosum 4.5e-06 4.5e-06 1 PMID:16845529 -2.7.1.77 * daucus carota 32.0 32.0 1 PMID:692392 -2.7.1.77 * gallus gallus 0.0021 0.0021 1 PMID:1164025 -2.7.1.77 * hordeum vulgare 180.0 151.5 2 PMID:3013235;PMID:6279651 -2.7.1.77 * leishmania tropica 130.0 130.0 1 * -2.7.1.77 * lupinus luteus 1.1 1.1 1 PMID:465504 -2.7.1.77 * morganella morganii 4.7 4.7 1 PMID:16232546 -2.7.1.77 * pantoea agglomerans 12.0 0.6 8 PMID:1083386;PMID:17206374 -2.7.1.78 * bos taurus 0.0167 0.00275 4 PMID:23843;PMID:6263631;PMID:7642718;PMID:9027586 -2.7.1.78 * homo sapiens 0.125 0.125 1 PMID:226541 -2.7.1.78 * mus musculus 0.0007 0.0007 1 PMID:6090142 -2.7.1.78 * rattus norvegicus 0.0418 0.0055 4 PMID:241638;PMID:2986715;PMID:3504;PMID:9027586 -2.7.1.78 * rhodothermus phage rm378 3.67 3.17 2 PMID:15579472 -2.7.1.78 * tequatrovirus t4 30.0 3.1 4 PMID:19082984;PMID:214125;PMID:4287929;PMID:6288679 -2.7.1.8 * vibrio cholerae serotype o1 92.5 92.5 1 PMID:11850417 -2.7.1.80 * propionibacterium freudenreichii subsp. shermanii 9.5 9.5 1 PMID:4337852 -2.7.1.81 * rattus norvegicus 0.114 0.114 1 PMID:4621658 -2.7.1.82 * glycine max 10.73 10.73 1 PMID:228735 -2.7.1.82 * plasmodium falciparum 1.3 1.3 1 PMID:19845508 -2.7.1.82 * rattus norvegicus 1.398 1.398 1 PMID:2992596 -2.7.1.85 * klebsiella aerogenes 45.0 26.3 2 PMID:5030625 -2.7.1.85 * klebsiella pneumoniae 24.0 24.0 1 PMID:12110692 -2.7.1.86 * arabidopsis thaliana 40.1 15.35 6 PMID:15347288;PMID:15711971 -2.7.1.86 * micrococcus flavus 8.66 5.85 2 PMID:15855156 -2.7.1.86 * mycobacterium tuberculosis 0.65 0.435 2 PMID:15855156 -2.7.1.86 * saccharomyces cerevisiae 729.0 0.5 5 PMID:16760478;PMID:2547755;PMID:4335000 -2.7.1.90 * acholeplasma laidlawii 12.0 12.0 1 PMID:3001032 -2.7.1.90 * ananas comosus 43.8 8.9 3 PMID:12223643;PMID:219853 -2.7.1.90 * brassica nigra 26.0 26.0 1 PMID:8819330 -2.7.1.90 * cucumis sativus 5.2 5.2 1 * -2.7.1.90 * daucus carota 2.0 2.0 1 * -2.7.1.90 * dictyoglomus thermophilum 24.4 24.4 1 PMID:10356999 -2.7.1.90 * entamoeba histolytica 298.0 42.85 6 PMID:15794763;PMID:178659;PMID:4372217 -2.7.1.90 * giardia duodenalis 146.0 146.0 1 PMID:7663168 -2.7.1.90 * glycine max 8.47 8.47 1 PMID:24241857 -2.7.1.90 * mesoplasma florum 0.00021 0.000185 2 PMID:3001032 -2.7.1.90 * musa cavendishii 13.9 13.9 1 PMID:12721855 -2.7.1.90 * naegleria fowleri 65.0 65.0 1 * -2.7.1.90 * oryza sativa 48.6 48.6 1 * -2.7.1.90 * phaseolus vulgaris 6.5 6.5 1 * -2.7.1.90 * porphyromonas gingivalis 278.0 278.0 1 PMID:11886747 -2.7.1.90 * propionibacterium freudenreichii subsp. shermanii 245.0 245.0 1 PMID:171261 -2.7.1.90 * rhodospirillum rubrum 24.2 24.2 1 * -2.7.1.90 * ricinus communis 8.25 8.25 1 PMID:16663429 -2.7.1.90 * saccharum hybrid cultivar 4.23 4.23 1 * -2.7.1.90 * sansevieria trifasciata 8.4 8.4 1 * -2.7.1.90 * solanum lycopersicum 1.72 1.72 1 * -2.7.1.90 * solanum tuberosum 30.2 10.0 5 PMID:11204201;PMID:12745260;PMID:3038023 -2.7.1.90 * spinacia oleracea 36.3 36.3 1 PMID:11523651 -2.7.1.90 * thermoproteus tenax 3.5 3.5 1 PMID:11265483 -2.7.1.90 * triticum aestivum 1.5 1.5 1 PMID:16667036 -2.7.1.90 * vigna radiata 74.0 43.0 2 PMID:3021198 -2.7.1.90 * xanthomonas campestris pv. campestris 59.0 58.5 2 PMID:24508689 -2.7.1.91 * bos taurus 0.00375 0.00375 1 PMID:181377 -2.7.1.91 * homo sapiens 43.4 19.34 3 PMID:15246004 -2.7.1.91 * mus musculus 0.00024 5e-05 8 PMID:12943676;PMID:15684337 -2.7.1.92 * klebsiella aerogenes 13.6 13.6 1 PMID:4328832 -2.7.10.2 * homo sapiens 0.0173 0.0173 1 PMID:12767803 -2.7.11.1 * arabidopsis thaliana 0.04 0.04 1 PMID:7916621 -2.7.11.1 * bos taurus 17.38 6.32 4 PMID:1322115;PMID:2159007;PMID:2539382;PMID:2835010 -2.7.11.1 * homo sapiens 0.25 0.25 1 PMID:18160308 -2.7.11.1 * oncorhynchus mykiss 0.07 0.07 1 PMID:4312674 -2.7.11.1 * saccharolobus solfataricus 0.0024 0.0024 1 PMID:10852877 -2.7.11.11 * homo sapiens 0.81 0.56 2 PMID:15039079 -2.7.11.11 * manduca sexta 0.266 0.266 1 PMID:15544940 -2.7.11.11 * mus musculus 5.3 5.3 1 PMID:15039079 -2.7.11.12 * homo sapiens 0.026 0.0155 4 PMID:12882934 -2.7.11.12 * plasmodium falciparum 0.0004 3.7e-05 5 PMID:16325279 -2.7.11.14 * bos taurus 1.2 0.0795 14 PMID:10736716;PMID:10737781;PMID:11665593;PMID:1527025;PMID:164024;PMID:2207073;PMID:2303419;PMID:2844754;PMID:3014340;PMID:3022791;PMID:6358791;PMID:8634260;PMID:9380677 -2.7.11.14 * enteroctopus dofleini 0.046 0.046 1 PMID:9516442 -2.7.11.15 * bos taurus 1.0 0.05 3 PMID:2765501;PMID:3036840;PMID:8096517 -2.7.11.17 * bos taurus 0.00067 0.00067 1 PMID:1587865 -2.7.11.17 * candida albicans 0.0035 0.0035 1 PMID:14577592 -2.7.11.17 * funaria hygrometrica 0.00069 0.00069 1 PMID:12711815 -2.7.11.17 * gallus gallus 0.00073 0.000585 4 PMID:3415667 -2.7.11.17 * homo sapiens 0.98 0.5075 2 PMID:12935886 -2.7.11.17 * ovis aries 0.022 0.022 1 PMID:8224219 -2.7.11.17 * rattus norvegicus 3.0 1.9 2 PMID:1846291 -2.7.11.18 * bos taurus 18.5 7.9 5 PMID:2034129;PMID:3426560;PMID:3553171;PMID:6311271;PMID:6897613;PMID:6934518 -2.7.11.18 * dictyostelium discoideum 0.00615 0.00615 1 PMID:2380188 -2.7.11.18 * gallus gallus 33.0 33.0 1 PMID:3881420 -2.7.11.18 * homo sapiens 3.1 3.1 1 PMID:156362 -2.7.11.18 * meleagris gallopavo 6.1 6.05 2 PMID:2034129;PMID:6894756;PMID:6897613 -2.7.11.18 * oryctolagus cuniculus 25.0 19.9 5 PMID:2034129;PMID:4853304;PMID:588245;PMID:6547715;PMID:7730316 -2.7.11.18 * ovis aries 7.7 6.550000000000001 2 PMID:1897991 -2.7.11.18 * rattus norvegicus 0.47 0.47 1 PMID:2730565 -2.7.11.18 * sus scrofa 7.9 7.9 1 PMID:2034129;PMID:3553171;PMID:6311271 -2.7.11.19 * bos taurus 8.3 5.99 2 PMID:6301372;PMID:6417452;PMID:6777382 -2.7.11.19 * gallus gallus 19.6 16.4 3 PMID:3089780;PMID:4029141 -2.7.11.19 * mus musculus 10.9 10.9 1 PMID:7601093 -2.7.11.19 * oryctolagus cuniculus 10.2 3.0949999999999998 12 PMID:14005;PMID:26632861;PMID:3426232;PMID:6417451;PMID:6417452;PMID:6777382 -2.7.11.19 * rattus norvegicus 0.426 0.426 1 PMID:6809757 -2.7.11.19 * squalus acanthias 2.8 2.8 1 PMID:7317377 -2.7.11.2 * ascaris suum 0.92 0.92 1 * -2.7.11.2 * bos taurus 0.332 0.33 3 PMID:3700404;PMID:6348044;PMID:6358789 -2.7.11.2 * caenorhabditis elegans 0.74 0.74 1 * -2.7.11.2 * homo sapiens 1.1 0.0505 10 PMID:10748134;PMID:12816949;PMID:15491150;PMID:15512796;PMID:8798399 -2.7.11.2 * rattus norvegicus 1.24 0.056 9 PMID:15512796;PMID:1644204;PMID:18627174 -2.7.11.2 * sus scrofa 1.9 1.9 1 PMID:3840997 -2.7.11.20 * homo sapiens 0.536 0.536 1 PMID:21605678 -2.7.11.23 * mus musculus 1.238 1.238 1 PMID:1956324 -2.7.11.23 * saccharomyces cerevisiae 65040.0 65040.0 1 PMID:2657724 -2.7.11.24 * zea mays 0.02042 0.00024 9 PMID:19424717 -2.7.11.26 * bos taurus 0.056 0.014950000000000001 4 PMID:1587865;PMID:7556643 -2.7.11.26 * homo sapiens 0.57 0.415 2 PMID:16923168 -2.7.11.28 * gallus gallus 0.0594 0.0299 2 PMID:3593768;PMID:6325440 -2.7.11.29 * bos taurus 0.0033 0.00224 2 PMID:3100530;PMID:3597414 -2.7.11.3 * rattus norvegicus 101.0 101.0 1 PMID:8910387 -2.7.11.31 * brassica oleracea 13.1 8.1905 2 PMID:8112324 -2.7.11.31 * rattus norvegicus 7.6 0.1805 6 PMID:1683469;PMID:18079111;PMID:3308873;PMID:6111317;PMID:6146523;PMID:8120043 -2.7.11.4 * rattus norvegicus 0.05 0.0357 5 PMID:10989428;PMID:2177326;PMID:3178224 -2.7.11.5 * escherichia coli 0.11 0.074 2 PMID:1310504;PMID:6329756 -2.7.11.7 * acanthamoeba castellanii 4.6 3.03 3 PMID:1851936;PMID:6309772 -2.7.11.7 * dictyostelium discoideum 2.1 0.98 3 PMID:1851940;PMID:2549052;PMID:3027076 -2.7.11.7 * gallus gallus 0.00063 0.00047500000000000005 2 PMID:2822719;PMID:3035322 -2.7.13.1 * saccharomyces cerevisiae 0.19 0.19 1 PMID:2026610 -2.7.13.3 * bacillus subtilis 2.3 2.3 1 PMID:18324779 -2.7.13.3 * vibrio cholerae o1 0.1805 0.11025 2 PMID:27670078 -2.7.2.1 * acetivibrio thermocellus 490.0 490.0 1 * -2.7.2.1 * acholeplasma laidlawii 205.9 205.9 1 PMID:217865 -2.7.2.1 * clostridium acetobutylicum 1087.0 557.35 2 PMID:9082921 -2.7.2.1 * desulfomicrobium sp. 1.39 1.39 1 PMID:25598851 -2.7.2.1 * desulfovibrio piger 6.16 6.16 1 PMID:25598851 -2.7.2.1 * ethanoligenens harbinense 42.12 42.12 1 PMID:17619101 -2.7.2.1 * geobacillus stearothermophilus 1530.0 765.855 2 PMID:29037 -2.7.2.1 * methanosarcina mazei 251.0 129.0 2 PMID:25088360 -2.7.2.1 * methanosarcina thermophila 656.0 620.0 2 PMID:11562377 -2.7.2.1 * nitratidesulfovibrio vulgaris 28.3 24.0 3 PMID:11226881 -2.7.2.1 * propionibacterium freudenreichii 2.4 2.4 1 * -2.7.2.1 * rhodopseudomonas palustris 3.16 3.16 1 PMID:3024667 -2.7.2.1 * salmonella enterica subsp. enterica serovar typhimurium 2400.0 2075.0 2 PMID:26448059 -2.7.2.1 * streptococcus pyogenes 282.0 282.0 1 * -2.7.2.1 * veillonella parvula 948.0 375.0 3 PMID:178662;PMID:216674;PMID:30411 -2.7.2.10 * entamoeba histolytica 52.0 52.0 1 PMID:4365563 -2.7.2.11 * pseudomonas aeruginosa 12.68 12.68 1 PMID:226082 -2.7.2.11 * saccharomyces cerevisiae 14.7 14.5 2 PMID:17449694;PMID:32748014 -2.7.2.14 * thermotoga maritima 12.0 12.0 1 PMID:12777787 -2.7.2.15 * escherichia coli 114.7 106.45 2 PMID:9484901 -2.7.2.16 * methanothermus fervidus 200.0 200.0 1 PMID:2226838;PMID:8159166 -2.7.2.18 * staphylococcus aureus 54.5 54.5 1 PMID:26774272 -2.7.2.2 * cryptobacterium curtum 1.4 1.4 1 PMID:17064396 -2.7.2.2 * enterococcus faecalis 3100.0 3100.0 1 * -2.7.2.2 * lactococcus lactis 3100.0 3100.0 1 * -2.7.2.2 * lentilactobacillus buchneri 59.52 59.52 1 PMID:3030360 -2.7.2.2 * metamycoplasma hominis 3100.0 3100.0 1 * -2.7.2.2 * neurospora crassa 3100.0 3100.0 1 * -2.7.2.2 * serratia marcescens 3100.0 3100.0 1 * -2.7.2.2 * slackia exigua 4.14 4.14 1 PMID:17064396 -2.7.2.2 * toxoplasma gondii 980.0 980.0 1 PMID:17379721 -2.7.2.2 * trichomonas vaginalis 1100.0 1100.0 1 PMID:10864518 -2.7.2.3 * abramis brama 560.0 560.0 1 PMID:367367 -2.7.2.3 * beta vulgaris 900.0 840.0 2 PMID:1261557;PMID:367367 -2.7.2.3 * bos taurus 710.0 565.5 4 PMID:10585490;PMID:367367;PMID:4604701 -2.7.2.3 * bufo vulgaris 470.0 470.0 1 PMID:367367 -2.7.2.3 * chrysophrys guttulatus 690.0 690.0 1 PMID:367367 -2.7.2.3 * clonorchis sinensis 530.0 530.0 1 PMID:10838223 -2.7.2.3 * columba sp. 620.0 620.0 1 PMID:367367 -2.7.2.3 * corynebacterium glutamicum 150.0 150.0 1 PMID:24593686 -2.7.2.3 * dromaius novaehollandiae 720.0 720.0 1 PMID:367367 -2.7.2.3 * equus caballus 1000.0 850.0 2 PMID:367367 -2.7.2.3 * escherichia coli 480.0 289.0 2 PMID:367367 -2.7.2.3 * gallus gallus 680.0 680.0 1 PMID:367367 -2.7.2.3 * geobacillus stearothermophilus 557.0 557.0 1 * -2.7.2.3 * hippoglossus stenolepis 810.0 810.0 1 PMID:6982068 -2.7.2.3 * homo sapiens 2260.0 650.0 11 PMID:1112804;PMID:11741981;PMID:182276;PMID:23336698;PMID:29995887;PMID:367367;PMID:4202713;PMID:5009693;PMID:5009694 -2.7.2.3 * hordeum vulgare 914.0 644.0 3 PMID:16667476 -2.7.2.3 * lactobacillus delbrueckii subsp. lactis 605.0 605.0 1 * -2.7.2.3 * macropus fuliginosus 650.0 650.0 1 PMID:367367 -2.7.2.3 * macropus giganteus 600.0 600.0 1 PMID:367367 -2.7.2.3 * methanococcus maripaludis 0.02 0.02 1 PMID:8288525 -2.7.2.3 * methanothermus fervidus 150.0 150.0 3 PMID:7588750 -2.7.2.3 * mus musculus 710.0 450.0 9 PMID:22905379;PMID:23844 -2.7.2.3 * oncorhynchus mykiss 720.0 720.0 1 PMID:367367 -2.7.2.3 * oryctolagus cuniculus 760.0 697.5 4 PMID:367367 -2.7.2.3 * ovis aries 720.0 700.0 3 PMID:367367;PMID:639826 -2.7.2.3 * phaeodactylum tricornutum 47.5 47.5 1 PMID:21816671 -2.7.2.3 * plasmodium falciparum 210.0 210.0 1 PMID:15158737 -2.7.2.3 * pseudocheirus peregrinus 690.0 690.0 1 PMID:367367 -2.7.2.3 * pseudomonas sp. 750.0 650.0 2 PMID:10753921 -2.7.2.3 * pyrococcus furiosus 0.022 0.0165 2 * -2.7.2.3 * pyrococcus woesei 75.0 75.0 1 PMID:7588750 -2.7.2.3 * rattus norvegicus 460.0 380.0 2 PMID:367367 -2.7.2.3 * saccharolobus solfataricus 8.69 8.69 1 PMID:8521845 -2.7.2.3 * saccharomyces cerevisiae 945.0 785.0 5 PMID:10092885;PMID:367367 -2.7.2.3 * salmo trutta 690.0 690.0 1 PMID:367367 -2.7.2.3 * schistosoma japonicum 125.0 125.0 1 PMID:26299245 -2.7.2.3 * spinacia oleracea 800.0 789.0 4 PMID:16667463;PMID:367367 -2.7.2.3 * spirulina geitleri 720.0 720.0 1 PMID:367367 -2.7.2.3 * sus scrofa 1000.0 850.0 2 PMID:367367 -2.7.2.3 * thermus thermophilus 259.0 259.0 1 PMID:457645 -2.7.2.3 * trichosurus vulpecula 700.0 700.0 1 PMID:367367 -2.7.2.3 * trout 700.0 700.0 1 PMID:367367 -2.7.2.3 * trypanosoma brucei 1311.0 331.5 4 PMID:6489338;PMID:9675273 -2.7.2.3 * vombatus sp. 1000.0 1000.0 1 * -2.7.2.3 * vombatus ursinus 700.0 700.0 1 PMID:367367 -2.7.2.3 * zymomonas mobilis 800.0 800.0 1 PMID:3026343 -2.7.2.4 * arabidopsis thaliana 18.87 2.7134 4 PMID:11812230;PMID:12602885;PMID:9241437 -2.7.2.4 * bacillus subtilis 30.0 3.2600000000000002 4 PMID:11471740;PMID:15033471;PMID:194888 -2.7.2.4 * corynebacterium glutamicum 0.034 0.034 1 PMID:7766138 -2.7.2.4 * escherichia coli 5.69 5.69 1 PMID:4551091 -2.7.2.4 * geobacillus stearothermophilus 0.046 0.046 1 PMID:5167534 -2.7.2.4 * lactiplantibacillus plantarum 0.29 0.179 6 PMID:16385120 -2.7.2.4 * paenibacillus polymyxa 22.2 22.2 1 PMID:6058940 -2.7.2.4 * pseudomonas fluorescens 11.16 11.16 1 PMID:4357740 -2.7.2.4 * saccharomyces cerevisiae 52.2 0.444 22 PMID:15358146;PMID:15645479 -2.7.2.4 * streptococcus mutans 13.92 13.92 1 PMID:26656 -2.7.2.4 * streptomyces noursei 0.13 0.13 1 PMID:17611754 -2.7.2.4 * thermotoga maritima 103.0 103.0 1 PMID:30175674 -2.7.2.4 * thermus thermophilus 58.6 35.3 2 PMID:16232547 -2.7.2.7 * clostridium acetobutylicum 402.0 402.0 1 PMID:3027059 -2.7.2.7 * clostridium tetanomorphum 64.3 64.3 1 PMID:14051802 -2.7.2.7 * dasytricha ruminantium 0.058 0.058 1 PMID:3924032 -2.7.2.8 * arabidopsis thaliana 24.0 18.0 2 PMID:16545809 -2.7.2.8 * escherichia coli 0.54 0.54 1 * -2.7.2.8 * maricaulis maris 20.1 13.455 2 PMID:22174908;PMID:23850694 -2.7.2.8 * neurospora crassa 7.21 7.21 1 PMID:6251078 -2.7.2.8 * pseudomonas aeruginosa 130.0 130.0 1 PMID:15342584 -2.7.2.8 * saccharolobus solfataricus 0.003 0.0019 2 * -2.7.2.8 * synechococcus elongatus 13.3 8.3 2 PMID:15502156 -2.7.2.8 * thermotoga maritima 677.0 361.0 2 PMID:15342584 -2.7.2.8 * xanthomonas campestris 44.05 23.0 2 PMID:17425781;PMID:23850694 -2.7.3.1 * nephtys caeca 65.0 65.0 1 PMID:5637051 -2.7.3.1 * perinereis sp. 45.3 45.3 1 * -2.7.3.2 * canis lupus familiaris 620.0 620.0 1 PMID:6698986 -2.7.3.2 * chaetopterus variopedatus 36.2 36.2 1 PMID:16962834 -2.7.3.2 * clupea harengus 511.0 223.0 6 PMID:15763518;PMID:25770046 -2.7.3.2 * gallus gallus 250.0 160.1 2 PMID:16962834;PMID:3674368 -2.7.3.2 * homo sapiens 410.0 245.5 5 PMID:17030001;PMID:6418727;PMID:6654916 -2.7.3.2 * mus musculus 50.25 46.864999999999995 2 PMID:16889687 -2.7.3.2 * oryctolagus cuniculus 276.0 261.0 7 PMID:16797013;PMID:17303563;PMID:17616428;PMID:19277488 -2.7.3.2 * tethya aurantium 31.8 31.8 1 PMID:16962834 -2.7.3.3 * drosophila melanogaster 154.0 154.0 1 PMID:4359471 -2.7.3.3 * euphausia superba 1780.0 1780.0 1 PMID:24690537 -2.7.3.3 * homarus americanus 212.0 212.0 1 PMID:4962497 -2.7.3.3 * limulus polyphemus 268.6 240.0 3 PMID:23262386;PMID:8925449;PMID:9041648 -2.7.3.3 * manduca sexta 248.0 248.0 1 PMID:193843 -2.7.3.3 * paracentrotus lividus 360.0 360.0 1 PMID:2836197 -2.7.3.3 * penaeus aztecus 46.3 46.3 1 PMID:9281313 -2.7.3.3 * penaeus japonicus 318.0 318.0 1 * -2.7.3.3 * penaeus vannamei 8.78 8.78 1 PMID:17496423 -2.7.3.3 * portunus trituberculatus 234.0 234.0 1 * -2.7.3.3 * steinernema carpocapsae 0.00312 0.002695 2 PMID:10461938 -2.7.3.3 * toxocara canis 40.3 40.3 1 PMID:17574244 -2.7.3.3 * trypanosoma brucei 0.288 0.288 1 PMID:11908902 -2.7.3.3 * trypanosoma cruzi 0.2539 0.2539 1 PMID:11908902 -2.7.3.4 * arenicola brasiliensis 28.71 5.16 5 PMID:16008553 -2.7.3.4 * arenicola marina 1283.0 1283.0 1 PMID:428380 -2.7.3.4 * riftia pachyptila 10.4 3.45 6 PMID:16188310 -2.7.3.5 * megascolides cameroni 49.0 40.0 2 PMID:5832288 -2.7.3.5 * urechis caupo 12.2 12.2 1 PMID:11866456 -2.7.3.9 * enterococcus faecalis 85.0 85.0 1 PMID:3922407 -2.7.3.9 * escherichia coli 95.0 95.0 1 PMID:6992959 -2.7.3.9 * salmonella enterica subsp. enterica serovar typhimurium 8929.0 8929.0 1 PMID:6754728 -2.7.3.9 * streptococcus salivarius 530.0 337.5 2 PMID:16716080;PMID:6673822 -2.7.4.1 * acinetobacter baylyi adp1 0.012 0.012 1 PMID:10473375 -2.7.4.1 * burkholderia cepacia 0.13 0.13 1 PMID:12419342 -2.7.4.1 * corynebacterium glutamicum 32.0 24.5 4 PMID:17545325 -2.7.4.1 * corynebacterium xerosis 0.15 0.15 1 PMID:14476999;PMID:4581493 -2.7.4.1 * dictyostelium discoideum 0.048 0.048 1 PMID:17940044 -2.7.4.1 * escherichia coli 1.07 0.15 3 PMID:13315368;PMID:14476999;PMID:2164013;PMID:4581493 -2.7.4.1 * hydrogenophilaceae bacterium 189.0 189.0 2 PMID:31907778 -2.7.4.1 * leishmania donovani 0.0442 0.01779 6 * -2.7.4.1 * meiothermus ruber 99.1 50.449999999999996 2 PMID:24532069 -2.7.4.1 * mycolicibacterium smegmatis 4.2 0.7 3 PMID:17630969;PMID:4337332 -2.7.4.1 * nocardioides dokdonensis 189.0 156.5 2 PMID:31907778 -2.7.4.1 * propionibacterium freudenreichii subsp. shermanii 0.73 0.73 1 PMID:3031044 -2.7.4.1 * pseudomonas aeruginosa 3223.3 645.0 11 PMID:12482933;PMID:26576296 -2.7.4.1 * rhodocyclus sp. 0.034 0.034 1 PMID:12324346 -2.7.4.1 * salmonella enterica subsp. enterica serovar minnesota 0.047 0.047 1 PMID:5003228 -2.7.4.1 * sinomonas atrocyanea 0.82 0.82 1 PMID:168307 -2.7.4.1 * thermosynechococcus vestitus 0.317 0.317 1 PMID:17368402 -2.7.4.10 * bos taurus 135.0 67.64 2 PMID:14401179;PMID:5423264 -2.7.4.10 * plasmodium falciparum 100.0 100.0 1 PMID:15478799 -2.7.4.10 * saccharomyces cerevisiae 0.1 0.1 1 PMID:15753074 -2.7.4.10 * sus scrofa 17.5 17.5 1 PMID:13693071 -2.7.4.11 * mus musculus 0.6 0.6 1 PMID:5862227 -2.7.4.12 * escherichia coli 24.16 24.16 1 PMID:13967158 -2.7.4.13 * saccharomyces cerevisiae 100.0 55.0 4 PMID:16240436 -2.7.4.13 * tequintavirus t5 232.0 78.685 16 PMID:12597877;PMID:14253449;PMID:14711503 -2.7.4.14 * homo sapiens 337.0 337.0 1 PMID:40615 -2.7.4.14 * rattus norvegicus 30.17 8.76 5 PMID:1125184;PMID:211381 -2.7.4.14 * saccharomyces cerevisiae 11.1 11.1 1 * -2.7.4.14 * tetrahymena pyriformis 27.5 27.5 1 PMID:211382;PMID:5350952 -2.7.4.16 * escherichia coli 0.000197 0.000197 1 PMID:4567662 -2.7.4.19 * xanthomonas oryzae 0.05 0.05 1 PMID:7082669 -2.7.4.2 * catharanthus roseus 0.21 0.21 1 * -2.7.4.2 * enterococcus faecalis 3.9 3.9 1 PMID:15802646 -2.7.4.2 * hevea brasiliensis 0.16 0.16 1 PMID:4333851 -2.7.4.2 * saccharomyces cerevisiae 0.06 0.06 1 PMID:13801508 -2.7.4.2 * sus scrofa 69.1 34.629999999999995 2 PMID:16973124;PMID:2991707;PMID:6248100 -2.7.4.21 * homo sapiens 0.007 0.007 1 PMID:29459425 -2.7.4.21 * rattus norvegicus 1.558 1.558 1 PMID:8633060 -2.7.4.22 * bacillus subtilis 39.1 24.5 8 PMID:12869195;PMID:17210578 -2.7.4.22 * enterococcus faecalis 19.4 9.399999999999999 4 PMID:17210578 -2.7.4.22 * escherichia coli 162.0 71.1 17 PMID:12869195;PMID:15256558;PMID:15857829;PMID:17210578;PMID:4568611;PMID:7711027;PMID:8679525;PMID:9457846 -2.7.4.22 * haemophilus influenzae 60.5 32.3 4 PMID:17210578 -2.7.4.22 * neisseria meningitidis 57.7 10.75 4 PMID:17210578 -2.7.4.22 * salmonella enterica subsp. enterica serovar typhimurium 134.3 0.032 14 PMID:15256558;PMID:17210578;PMID:4568611 -2.7.4.22 * staphylococcus aureus 23.6 18.15 4 PMID:17210578 -2.7.4.22 * streptococcus pneumoniae 666.0 130.0 11 PMID:15324307;PMID:17210578 -2.7.4.22 * vibrio vulnificus 0.01238 0.009255 2 PMID:17371864 -2.7.4.23 * escherichia coli 8.3 0.075 4 PMID:12700258 -2.7.4.24 * homo sapiens 0.007 0.007 1 PMID:29459425 -2.7.4.25 * salmonella enterica subsp. enterica serovar typhimurium 0.0177 0.0177 1 PMID:4373439 -2.7.4.29 * escherichia coli 13700.0 12800.0 2 PMID:18047581 -2.7.4.3 * ancylobacter novellus 32.0 32.0 1 * -2.7.4.3 * bacillus subtilis 350.0 350.0 1 PMID:8061005 -2.7.4.3 * bos taurus 2244.0 1062.0 5 PMID:17453945;PMID:207226;PMID:6296114 -2.7.4.3 * cereibacter sphaeroides 76.7 76.7 1 * -2.7.4.3 * cyprinus carpio 3320.0 3320.0 1 PMID:164348 -2.7.4.3 * desulfovibrio desulfuricans 1640.0 1640.0 1 PMID:18328566 -2.7.4.3 * doryteuthis pealeii 2700.0 2700.0 1 PMID:12179 -2.7.4.3 * escherichia coli 2400.0 2400.0 1 PMID:1554691 -2.7.4.3 * gallus gallus 811.0 811.0 1 PMID:6281013 -2.7.4.3 * geobacillus stearothermophilus 3000.0 3000.0 1 PMID:1554691 -2.7.4.3 * halothiobacillus neapolitanus 79.5 79.5 1 PMID:4357664 -2.7.4.3 * homo sapiens 3200.0 252.5 16 PMID:16361259;PMID:17662886;PMID:1969292;PMID:211388;PMID:22038794;PMID:5062950;PMID:6182143;PMID:6296114 -2.7.4.3 * megalodesulfovibrio gigas 2170.0 2000.0 4 PMID:18328566 -2.7.4.3 * methanocaldococcus jannaschii 89.0 89.0 1 PMID:7768791 -2.7.4.3 * methanococcus voltae 14.0 14.0 1 PMID:7768791 -2.7.4.3 * methanothermococcus thermolithotrophicus 81.0 81.0 1 PMID:7768791 -2.7.4.3 * methanotorris igneus 56.0 56.0 1 PMID:7768791 -2.7.4.3 * mus musculus 1.4 1.2 3 PMID:16361259 -2.7.4.3 * mycobacterium marinum 576.0 576.0 1 PMID:3004585 -2.7.4.3 * oryctolagus cuniculus 2200.0 1600.0 3 PMID:10428790;PMID:6296114 -2.7.4.3 * plasmodium falciparum 100.0 55.0 2 PMID:15478799;PMID:18973776 -2.7.4.3 * rattus norvegicus 1900.0 1300.0 4 PMID:6244854 -2.7.4.3 * rhodopseudomonas palustris 76.7 76.7 1 * -2.7.4.3 * rhodopseudomonas rubrum 76.7 76.7 1 * -2.7.4.3 * saccharomyces cerevisiae 1900.0 1900.0 1 * -2.7.4.3 * sulfolobus acidocaldarius 12.15 12.15 1 PMID:8489243 -2.7.4.3 * sus scrofa 1810.0 1810.0 1 * -2.7.4.3 * thermotoga neapolitana 8400.0 4725.0 2 PMID:12625835 -2.7.4.3 * vibrio natriegens 1450.0 1450.0 1 * -2.7.4.3 * zea mays 1550.0 1550.0 1 PMID:16664952 -2.7.4.31 * methanocaldococcus jannaschii 0.16 0.11599999999999999 2 PMID:26100040 -2.7.4.33 * acinetobacter johnsonii 9570.0 39.9 6 PMID:15716459;PMID:1655714 -2.7.4.33 * cellulosimicrobium cellulans 0.01 0.01 1 PMID:8386121 -2.7.4.33 * leishmania donovani 0.0005 0.00047 3 * -2.7.4.33 * meiothermus ruber 2.7 2.1500000000000004 2 PMID:24532069 -2.7.4.33 * myxococcus xanthus 12.0 12.0 1 PMID:16233039 -2.7.4.34 * francisella tularensis subsp. tularensis 0.244 0.244 1 PMID:26582818 -2.7.4.34 * pseudomonas aeruginosa 474.0 474.0 1 PMID:12482933 -2.7.4.6 * arabidopsis thaliana 12.1 12.1 1 PMID:28586477 -2.7.4.6 * avena sativa 1736.0 1736.0 1 PMID:8038216 -2.7.4.6 * bos taurus 360.0 360.0 1 PMID:5056081 -2.7.4.6 * halobacterium salinarum 340.0 340.0 1 PMID:15251445 -2.7.4.6 * halomonas sp. 1200.0 1200.0 2 PMID:17227453 -2.7.4.6 * halomonas sp. #593 1000.0 1000.0 1 PMID:18573868 -2.7.4.6 * homo sapiens 800.0 770.0 4 PMID:1851158;PMID:2546816 -2.7.4.6 * lathyrus oleraceus 5100.0 108.05 10 PMID:15466238;PMID:20458498 -2.7.4.6 * leishmania amazonensis 6427.0 3317.0 2 PMID:18242727 -2.7.4.6 * leishmania major 4341.0 4341.0 1 PMID:16809050 -2.7.4.6 * pseudomonas sp. 1500.0 1500.0 3 PMID:17227453;PMID:18573868 -2.7.4.6 * saccharomyces cerevisiae 5.4 5.4 1 PMID:1659321 -2.7.4.6 * saccharomyces pastorianus 1600.0 1600.0 1 PMID:14114857 -2.7.4.6 * saccharum officinarum 8.3e-06 8.3e-06 1 PMID:8016268 -2.7.4.6 * spinacia oleracea 2160.0 1705.0 2 PMID:1849013 -2.7.4.6 * streptomyces coelicolor 400.0 400.0 1 PMID:8706710 -2.7.4.6 * sus scrofa 2026.0 1763.0 2 PMID:6092068;PMID:6269456 -2.7.4.6 * xenopus laevis 125.0 125.0 1 PMID:2176546 -2.7.4.8 * bos taurus 354.0 338.5 2 PMID:3024975 -2.7.4.8 * escherichia coli 187.0 187.0 1 PMID:211389 -2.7.4.8 * mus musculus 1.24 0.84 2 PMID:11742110;PMID:5862227 -2.7.4.8 * plasmodium falciparum 750.0 390.0 2 PMID:18374996 -2.7.4.8 * rattus norvegicus 3.2 3.2 1 PMID:4307347 -2.7.4.8 * rickettsia conorii 999.0 999.0 2 PMID:16891376 -2.7.4.8 * saccharomyces cerevisiae 1581.0 571.0 3 PMID:12482754;PMID:2551688;PMID:6118179 -2.7.4.8 * sus scrofa 28.0 28.0 1 PMID:211390 -2.7.4.9 * gallus gallus 0.188 0.188 1 PMID:236732 -2.7.4.9 * homo sapiens 0.833 0.821 2 PMID:18469;PMID:2538159 -2.7.4.9 * mus musculus 12.76 6.3919999999999995 2 PMID:4323166;PMID:4711469 -2.7.4.9 * plasmodium falciparum 15.0 9.75 4 PMID:18477629 -2.7.4.9 * saccharomyces cerevisiae 0.0029 0.0029 1 PMID:19540237 -2.7.6.1 * [bacillus] caldolyticus 440.0 440.0 1 PMID:15560793 -2.7.6.1 * bacillus subtilis 190.0 190.0 1 PMID:2169413 -2.7.6.1 * eremothecium gossypii 0.01 0.01 1 PMID:18782443 -2.7.6.1 * homo sapiens 35.7 22.2 5 PMID:169259;PMID:8387514;PMID:8702702 -2.7.6.1 * mycobacterium tuberculosis 1.16 0.594 2 PMID:22745722 -2.7.6.1 * pyrobaculum calidifontis 480.0 480.0 1 PMID:27517698 -2.7.6.1 * rattus norvegicus 39.1 7.48 15 PMID:1651917;PMID:211372;PMID:2546925;PMID:4359485;PMID:9348095;PMID:9366267 -2.7.6.1 * salmonella enterica 0.094 0.094 1 PMID:19959576 -2.7.6.1 * salmonella enterica subsp. enterica serovar typhimurium 130.0 130.0 1 PMID:211378 -2.7.6.1 * spinacia oleracea 13.1 0.089 17 PMID:11278632;PMID:9952445 -2.7.6.2 * candida albicans 0.000367 0.000367 1 PMID:18652651 -2.7.6.2 * glycine max 6.1e-05 6.1e-05 1 PMID:16661427 -2.7.6.2 * homo sapiens 0.0602 0.0602 1 PMID:12953792 -2.7.6.2 * paracoccus denitrificans 0.0235 0.0235 1 PMID:6251035 -2.7.6.2 * petroselinum crispum 0.000722 0.000722 1 PMID:220503 -2.7.6.2 * plasmodium falciparum 999.0 0.017 5 PMID:17132104 -2.7.6.2 * rattus norvegicus 0.0047 0.0047 1 PMID:220502 -2.7.6.2 * sus scrofa 0.00165 0.00165 1 PMID:239748 -2.7.6.3 * escherichia coli 2.1 2.1 1 PMID:1657875 -2.7.6.4 * streptomyces adephospholyticus 915.0 915.0 1 * -2.7.6.5 * mycobacterium tuberculosis 0.03 0.0275 4 PMID:16026164 -2.7.6.5 * streptomyces antibioticus 1.14 1.14 1 PMID:8113189 -2.7.7.1 * bos taurus 16.7 16.7 1 PMID:7654174 -2.7.7.1 * escherichia coli 0.068 0.014 4 PMID:4291828 -2.7.7.1 * gallus gallus 31.0 31.0 1 PMID:16567 -2.7.7.1 * homo sapiens 76.5 15.2 6 PMID:11027696;PMID:12359228;PMID:14516279;PMID:1524439 -2.7.7.1 * leishmania braziliensis 28.22 28.22 1 PMID:26318236 -2.7.7.1 * methanocaldococcus jannaschii 187.0 187.0 1 PMID:11265471 -2.7.7.1 * saccharolobus solfataricus 8.8 5.075 2 PMID:11265470;PMID:7988679;PMID:9211320 -2.7.7.1 * saccharomyces cerevisiae 74.2 5.0 9 PMID:10428462;PMID:11966438;PMID:2832206;PMID:3013296;PMID:4291828;PMID:9211320 -2.7.7.1 * sus scrofa 40.0 20.055 2 PMID:1090;PMID:6256240 -2.7.7.10 * bifidobacterium bifidum 17.0 17.0 1 PMID:718964 -2.7.7.10 * cucumis melo 190.7 190.7 1 * -2.7.7.10 * cucumis sativus 3.8 0.56 3 PMID:24276942 -2.7.7.10 * entamoeba histolytica 135.0 135.0 1 * -2.7.7.10 * homo sapiens 0.0027 0.0026 2 PMID:5018270 -2.7.7.101 * escherichia coli 1.09 1.09 1 PMID:340457 -2.7.7.12 * bifidobacterium bifidum 93.1 0.334 5 PMID:24014529 -2.7.7.12 * bos taurus 25.7 19.05 2 PMID:1259429 -2.7.7.12 * escherichia coli 1080.0 180.0 8 PMID:10529216;PMID:10820011;PMID:12418221;PMID:3022797;PMID:5338129;PMID:7727423;PMID:7873670;PMID:9772178 -2.7.7.12 * galdieria sulphuraria 137.0 137.0 1 PMID:8529650 -2.7.7.12 * homo sapiens 122.0 16.8 11 PMID:10037750;PMID:6260202;PMID:6272638;PMID:6287937;PMID:736561;PMID:7957929;PMID:8900165;PMID:9323558;PMID:9450900 -2.7.7.12 * saccharomyces cerevisiae 54.1 54.1 1 PMID:387754;PMID:6292668 -2.7.7.13 * arthrobacter sp. 2.4 2.4 1 PMID:14245350 -2.7.7.13 * leptospira interrogans serovar copenhageni 3.8 3.8 1 PMID:20035319 -2.7.7.13 * mycolicibacterium smegmatis 2.99 2.99 1 PMID:9989944 -2.7.7.13 * pyrococcus horikoshii 10.2 8.2 6 PMID:26290359 -2.7.7.13 * salmonella enterica 2.75 2.75 1 PMID:8922954 -2.7.7.13 * sus scrofa 24.1 16.675 2 PMID:2983993;PMID:7688733 -2.7.7.13 * trypanosoma brucei 0.34 0.34 1 PMID:19919534 -2.7.7.14 * rattus norvegicus 6.505 4.38 3 PMID:1323040;PMID:241749;PMID:8385107 -2.7.7.14 * trypanosoma brucei 1.55 1.55 1 PMID:19555461 -2.7.7.15 * caenorhabditis elegans 11.0 10.5 2 PMID:11566446;PMID:19836342 -2.7.7.15 * lathyrus oleraceus 0.1096 0.1096 1 * -2.7.7.15 * rattus norvegicus 47.5 2.5615 12 PMID:1323039;PMID:1660305;PMID:19783652;PMID:3007491;PMID:670184;PMID:914832;PMID:985506 -2.7.7.15 * ricinus communis 1.518 1.0602 2 PMID:16667443;PMID:2552923 -2.7.7.15 * saccharomyces cerevisiae 196.0 196.0 1 PMID:11162399 -2.7.7.15 * streptococcus pneumoniae 37.0 2.5 3 PMID:11466299;PMID:11786295;PMID:8837483 -2.7.7.18 * bacillus subtilis 11.5 6.449999999999999 6 PMID:11704676 -2.7.7.18 * escherichia coli 0.024 0.0024000000000000002 4 PMID:4291828 -2.7.7.18 * nicotiana tabacum 0.00358 0.00269 3 PMID:24241228 -2.7.7.18 * saccharomyces cerevisiae 5.0 3.835 4 PMID:4291828 -2.7.7.19 * artemia salina 0.0939 0.0939 1 PMID:2982613 -2.7.7.19 * bos taurus 28.33 28.33 1 PMID:237901 -2.7.7.19 * homo sapiens 3175.0 3175.0 1 PMID:8717411 -2.7.7.2 * bacillus subtilis 0.58 0.58 1 PMID:9473052 -2.7.7.2 * homo sapiens 6.8 0.03 5 PMID:16643857;PMID:17049878;PMID:20060505 -2.7.7.2 * methanocaldococcus jannaschii 0.01 0.004 3 PMID:20822113 -2.7.7.2 * rattus norvegicus 0.133 0.06960000000000001 2 PMID:2557903;PMID:3034893;PMID:9211336 -2.7.7.2 * saccharomyces cerevisiae 0.00138 0.00138 1 PMID:19994476 -2.7.7.23 * bos taurus 330.0 330.0 1 PMID:13672971 -2.7.7.23 * escherichia coli 20.4 17.75 2 PMID:8083170;PMID:8689233 -2.7.7.23 * giardia duodenalis 72.0 39.3 3 PMID:15951138;PMID:16169849;PMID:9763295 -2.7.7.23 * neurospora crassa 8.66 8.66 1 PMID:43769 -2.7.7.23 * ovis aries 0.17 0.17 1 PMID:13733356 -2.7.7.23 * saccharomyces cerevisiae 15.1 15.1 1 * -2.7.7.23 * staphylococcus aureus 2390.0 2390.0 1 PMID:13672971 -2.7.7.23 * sulfurisphaera tokodaii 2.2 2.2 1 PMID:25567746 -2.7.7.23 * sus scrofa 14.9 14.9 1 PMID:8662687 -2.7.7.24 * acinetobacter calcoaceticus 2.31 2.31 1 * -2.7.7.24 * escherichia coli 360.0 277.0 2 PMID:11697907 -2.7.7.24 * mycobacterium tuberculosis 0.0569 0.0569 1 PMID:9084178 -2.7.7.24 * mycolicibacterium smegmatis 0.097 0.097 1 PMID:9084178 -2.7.7.24 * pseudomonas aeruginosa 44.8 44.8 1 PMID:13753209 -2.7.7.24 * streptomyces antibioticus 53.67 53.67 1 * -2.7.7.24 * streptomyces sp. 0.0801 0.004 5 PMID:15179042;PMID:18051285 -2.7.7.24 * sulfurisphaera tokodaii 9.4 5.375 2 PMID:15598657 -2.7.7.27 * aeromonas caviae 0.066 0.014 3 PMID:345767 -2.7.7.27 * aeromonas hydrophila 28.2 0.066 3 PMID:6331331 -2.7.7.27 * agrobacterium tumefaciens 129.0 37.5 4 PMID:12135365 -2.7.7.27 * anabaena sp. 111.0 111.0 1 PMID:16668507 -2.7.7.27 * arabidopsis thaliana 17.0 5.0 26 PMID:12748181;PMID:18614708 -2.7.7.27 * cereibacter sphaeroides 172.0 170.0 2 PMID:10562432;PMID:6178721 -2.7.7.27 * chlamydomonas reinhardtii 81.0 81.0 1 PMID:8016263 -2.7.7.27 * citrobacter freundii 0.45 0.45 1 PMID:4396287 -2.7.7.27 * escherichia coli 148.0 31.5 16 PMID:12135365;PMID:16530732;PMID:19208694;PMID:21741429;PMID:4369095;PMID:6156933;PMID:826540;PMID:9587413 -2.7.7.27 * hafnia alvei 2.5 2.5 1 PMID:6331331 -2.7.7.27 * hordeum vulgare 28.6 12.3 3 PMID:12586892;PMID:9426234 -2.7.7.27 * nitrosomonas europaea 20.0 20.0 1 PMID:22961847 -2.7.7.27 * oryza sativa 0.03 0.03 1 PMID:19208694 -2.7.7.27 * rhodocyclus tenuis 114.0 114.0 1 PMID:6263861 -2.7.7.27 * rhodospirillum rubrum 64.0 64.0 1 * -2.7.7.27 * salmonella enterica subsp. enterica serovar typhimurium 106.0 53.48 2 PMID:4369095;PMID:4396287;PMID:6156933 -2.7.7.27 * serratia marcescens 0.287 0.206 2 PMID:6432 -2.7.7.27 * solanum lycopersicum 65.0 65.0 1 * -2.7.7.27 * solanum tuberosum 42.0 2.8499999999999996 8 PMID:16662422;PMID:17137579;PMID:18715954;PMID:7480324 -2.7.7.27 * spinacia oleracea 156.0 90.0 2 PMID:16662079;PMID:5922972 -2.7.7.27 * synechocystis sp. 134.0 134.0 1 PMID:16668507 -2.7.7.27 * thermus caldophilus 161.7 161.7 1 PMID:8921008 -2.7.7.27 * triticum aestivum 58.5 30.45 2 PMID:11855648 -2.7.7.27 * zea mays 41.1 15.2 7 PMID:15951484;PMID:16658078;PMID:16665182;PMID:18715954;PMID:25600571;PMID:758958 -2.7.7.28 * bos taurus 0.38 0.38 1 PMID:5946626 -2.7.7.3 * corynebacterium ammoniagenes 8.5 8.5 1 PMID:8389542 -2.7.7.3 * escherichia coli 22.3 15.7 2 PMID:10480925 -2.7.7.3 * pyrococcus abyssi 0.07 0.07 1 PMID:15642482 -2.7.7.3 * rattus norvegicus 300.0 234.0 2 * -2.7.7.3 * sus scrofa 7.61 7.61 1 PMID:6312972 -2.7.7.30 * arabidopsis thaliana 0.71 0.71 1 PMID:18199744 -2.7.7.30 * sus scrofa 0.0036 0.0036 1 PMID:5646162 -2.7.7.33 * azotobacter vinelandii 0.0375 0.0375 1 PMID:5933869 -2.7.7.33 * salmonella enterica 10.3 10.3 1 PMID:8276783 -2.7.7.33 * salmonella enterica subsp. enterica serovar paratyphi a 0.408 0.408 1 PMID:14299608 -2.7.7.33 * yersinia pseudotuberculosis 2.51 1.3264999999999998 2 PMID:4833746;PMID:8144449 -2.7.7.34 * mus musculus 0.046 0.046 1 PMID:6034677 -2.7.7.34 * pyrococcus horikoshii 7.3 2.85 4 PMID:26290359 -2.7.7.35 * euglena gracilis 1.3 0.905 2 PMID:4287446;PMID:5970863 -2.7.7.37 * pyrococcus horikoshii 10.2 10.2 1 PMID:26290359 -2.7.7.37 * saccharomyces cerevisiae 0.178 0.178 1 PMID:14299635 -2.7.7.38 * escherichia coli 3300.0 30.05 4 PMID:5330266;PMID:6259128;PMID:6285137;PMID:7606392;PMID:7875563 -2.7.7.39 * bacillus subtilis 85.7 85.7 1 PMID:8393871 -2.7.7.4 * allium cepa 15.25 12.96 4 PMID:17692849 -2.7.7.4 * allochromatium vinosum 433.0 433.0 1 PMID:24073218 -2.7.7.4 * aquifex aeolicus 0.013 0.013 1 PMID:17095009 -2.7.7.4 * archaeoglobus fulgidus 33.9 17.5 2 PMID:9627961 -2.7.7.4 * astragalus bisulcatus 0.031 0.031 1 PMID:4377098 -2.7.7.4 * astragalus hamosus 0.0141 0.0141 1 PMID:4377098 -2.7.7.4 * astragalus racemosus 0.026 0.026 1 PMID:4377098 -2.7.7.4 * astragalus sinicus 0.0337 0.0337 1 PMID:4377098 -2.7.7.4 * brassica capitata 38.0 17.15 4 PMID:16662476 -2.7.7.4 * desulfomicrobium sp. 1.12 1.05 2 PMID:25816613 -2.7.7.4 * desulfovibrio desulfuricans 22.5 22.5 1 PMID:9819214 -2.7.7.4 * desulfovibrio piger 2.94 2.5999999999999996 2 PMID:25816613 -2.7.7.4 * euglena gracilis 237.7 221.45 2 PMID:1904773 -2.7.7.4 * geobacillus stearothermophilus 7.04 7.04 1 * -2.7.7.4 * glycine max 48.7 25.8 2 PMID:16684499 -2.7.7.4 * heliocidaris crassispina 12.96 12.96 1 PMID:6243988 -2.7.7.4 * homo sapiens 0.00012 0.00012 1 PMID:15065880 -2.7.7.4 * megalodesulfovibrio gigas 28.9 28.9 1 PMID:9819214 -2.7.7.4 * mus musculus 9.3 9.3 1 PMID:4333584 -2.7.7.4 * rattus norvegicus 14.2 2.953 3 PMID:2537056;PMID:3034891;PMID:718962 -2.7.7.4 * rhodovulum sulfidophilum 2.47 2.47 1 * -2.7.7.4 * saccharomyces cerevisiae 140.0 70.345 2 PMID:10092498;PMID:4582048 -2.7.7.4 * spinacia oleracea 267.0 257.0 2 PMID:8274013 -2.7.7.4 * synechococcus sp. 833.0 833.0 1 * -2.7.7.4 * thiobacillus denitrificans atcc 25259 352.0 191.75 2 PMID:19664586 -2.7.7.4 * zea mays 0.000246 0.0001263 2 PMID:16658609 -2.7.7.40 * haemophilus influenzae 37.5 26.6 2 PMID:10094675 -2.7.7.41 * escherichia coli 30.79 15.408999999999999 2 PMID:1323037;PMID:2995359;PMID:30751 -2.7.7.41 * homo sapiens 4.5 3.45 2 PMID:25375833 -2.7.7.41 * micrococcus cerificans 0.1333 0.1333 1 PMID:5679981 -2.7.7.41 * saccharomyces cerevisiae 1.409 0.9295 2 PMID:2822695;PMID:350877 -2.7.7.41 * sus scrofa 0.00011 0.00011 1 PMID:6288204 -2.7.7.43 * [haemophilus] ducreyi 12.66 12.66 1 PMID:8663048 -2.7.7.43 * bos taurus 18.25 18.25 1 PMID:10207180 -2.7.7.43 * danio rerio 4.5 2.7 5 PMID:22351762 -2.7.7.43 * escherichia coli 2.1 1.05565 2 PMID:14960566;PMID:2826425 -2.7.7.43 * homo sapiens 0.045 0.045 1 PMID:6084482 -2.7.7.43 * pelophylax lessonae 0.542 0.542 1 PMID:6253375 -2.7.7.43 * photobacterium leiognathi 0.165 0.165 1 PMID:21228490 -2.7.7.43 * rattus norvegicus 2.0 2.0 1 PMID:1577759 -2.7.7.43 * streptococcus sp. 0.354 0.354 1 PMID:7961510 -2.7.7.43 * sus scrofa 1.58 1.205 2 PMID:4288894 -2.7.7.44 * glycine max 0.112 0.0502 6 * -2.7.7.44 * hordeum vulgare 3.8 3.8 1 PMID:5570433 -2.7.7.45 * artemia salina 0.003 0.003 1 PMID:4208243 -2.7.7.45 * artemia sp. 0.113 0.113 1 PMID:8163476 -2.7.7.46 * escherichia coli 0.274 0.20400000000000001 2 PMID:6324682 -2.7.7.47 * bacillus subtilis 4.6e-05 4.6e-05 1 * -2.7.7.47 * escherichia coli 0.0115 0.0115 1 PMID:15721775 -2.7.7.47 * pseudomonas aeruginosa 1.3 1.3 1 PMID:29124199 -2.7.7.48 * black beetle virus 1.6e-07 1.6e-07 1 PMID:16789214 -2.7.7.48 * brome mosaic virus 1.88e-07 1.88e-07 1 PMID:2389551 -2.7.7.48 * cucumber mosaic virus 0.13 0.0015 5 PMID:2001739;PMID:4372786;PMID:462818 -2.7.7.48 * encephalomyocarditis virus 0.00184 0.00184 1 PMID:5614 -2.7.7.48 * halobacterium salinarum 0.0224 0.0224 1 PMID:4638791 -2.7.7.48 * hepacivirus hominis 0.025 0.012675 2 PMID:10889032;PMID:9624134 -2.7.7.48 * rhinovirus a2 0.00196 0.00196 1 PMID:2981346 -2.7.7.48 * solanum lycopersicum 0.0166 0.0166 1 PMID:7685022 -2.7.7.48 * vigna unguiculata 0.0057 0.0057 1 PMID:18635112 -2.7.7.49 * avian myeloblastosis virus 0.000104 0.000104 1 * -2.7.7.49 * simian immunodeficiency virus 0.135 0.101 2 PMID:1691922;PMID:1698157 -2.7.7.5 * acidianus ambivalens 0.043 0.043 1 PMID:10415168 -2.7.7.5 * saccharomyces cerevisiae 0.8 0.41500000000000004 2 PMID:329837;PMID:4564258 -2.7.7.5 * saccharomyces fragilis 16.0 16.0 1 PMID:5964041 -2.7.7.5 * thiobacillus denitrificans 2100.0 2100.0 1 PMID:10636864 -2.7.7.50 * bos taurus 3e-05 3e-05 1 PMID:6324112;PMID:6329686 -2.7.7.50 * homo sapiens 7e-05 6.8e-05 2 PMID:7358712 -2.7.7.50 * orthopoxvirus vaccinia 2.58 0.015135 4 PMID:1194286;PMID:2164022;PMID:2164023;PMID:659428 -2.7.7.50 * saccharomyces cerevisiae 7.27 0.00723 3 PMID:3029058;PMID:6324112;PMID:6329686;PMID:6389537 -2.7.7.52 * leishmania tarentolae 8.2 7.435 2 PMID:11893335 -2.7.7.53 * chlorella vulgaris 0.00096 0.00096 1 PMID:8198532 -2.7.7.53 * dolichospermum flos-aquae 0.037 0.037 1 PMID:9003364 -2.7.7.53 * mycobacterium tuberculosis 10.84 6.925 2 PMID:19778616 -2.7.7.53 * saccharomyces cerevisiae 55.0 36.9 2 PMID:2163260;PMID:2982863 -2.7.7.53 * scenedesmus basiliensis 0.0012 0.0012 1 PMID:8198532 -2.7.7.53 * scenedesmus quadricauda 0.00014 0.00014 1 PMID:8198532 -2.7.7.53 * tetradesmus obliquus 1.96 0.980325 2 PMID:8198532 -2.7.7.56 * escherichia coli 1.6 0.8700000000000001 2 PMID:1512252 -2.7.7.6 * anabaena sp. 0.0156 0.0156 1 * -2.7.7.6 * bos taurus 0.05 0.05 1 PMID:5289245 -2.7.7.6 * clostridium acetobutylicum 0.0527 0.0527 1 PMID:1705930 -2.7.7.6 * lathyrus oleraceus 0.006 0.0031715 2 PMID:1991470 -2.7.7.6 * pseudomonas aeruginosa 0.000178 0.000178 1 PMID:3125844 -2.7.7.6 * rattus norvegicus 0.05 0.05 1 PMID:5289245 -2.7.7.6 * rickettsia prowazekii 0.0168 0.0168 1 PMID:2120186 -2.7.7.6 * saccharomyces cerevisiae 0.224 0.224 1 PMID:2179949 -2.7.7.6 * schizosaccharomyces pombe 0.6 0.6 1 PMID:8367291 -2.7.7.6 * staphylococcus aureus 0.0813 0.0813 1 PMID:7695614 -2.7.7.6 * thermus thermophilus 0.03 0.03 1 PMID:2384094 -2.7.7.6 * vectrevirus k1e 4600.0 4600.0 1 PMID:20596705 -2.7.7.60 * arabidopsis thaliana 67.0 50.0 2 PMID:10841550 -2.7.7.60 * escherichia coli 23.0 23.0 1 PMID:10518523 -2.7.7.60 * mycobacterium tuberculosis 7.8 7.8 1 PMID:18047786 -2.7.7.60 * streptomyces coelicolor 0.00335 0.00335 1 PMID:11408165 -2.7.7.62 * salmonella enterica subsp. enterica serovar typhimurium 0.00067 0.000436 2 PMID:10869342;PMID:7559521 -2.7.7.64 * arabidopsis thaliana 86.9 47.95 6 PMID:17341835 -2.7.7.64 * cucumis melo 678.0 321.5 4 PMID:16829585 -2.7.7.64 * lathyrus oleraceus 95.0 63.9 3 PMID:15326166 -2.7.7.65 * caulobacter vibrioides 0.16 0.08166 4 PMID:17640875 -2.7.7.68 * methanocaldococcus jannaschii 3.5 2.8 4 PMID:18260642 -2.7.7.69 * arabidopsis thaliana 15.1 14.649999999999999 2 PMID:18463094 -2.7.7.7 * [bacillus] caldotenax 33.3 33.3 1 PMID:1320608 -2.7.7.7 * [bacillus] caldovelox 20.8 20.8 1 PMID:1320608 -2.7.7.7 * bacillus subtilis 0.4 0.083 3 PMID:4211828;PMID:4957767 -2.7.7.7 * bombyx mori 0.031 0.023 2 PMID:8101841 -2.7.7.7 * chenopodium album 0.523 0.523 1 PMID:8177736 -2.7.7.7 * crithidia fasciculata 0.12 0.12 1 PMID:1537858 -2.7.7.7 * drosophila melanogaster 0.59 0.59 1 PMID:1360647 -2.7.7.7 * escherichia coli 2.4 1.2329999999999999 2 PMID:4211910;PMID:4605284 -2.7.7.7 * gallus gallus 5.83 5.83 1 * -2.7.7.7 * geobacillus kaue 37.0 37.0 1 PMID:21870126 -2.7.7.7 * geobacillus stearothermophilus 26.7 26.7 1 PMID:1320608 -2.7.7.7 * herpes simplex virus 0.795 0.795 1 * -2.7.7.7 * homo sapiens 5.33 3.43 3 PMID:1556099 -2.7.7.7 * leishmania mexicana 0.00019 0.00019 1 PMID:1576158 -2.7.7.7 * mesocentrotus franciscanus 0.027 0.027 1 PMID:4859478 -2.7.7.7 * micrococcus luteus 0.66 0.66 1 PMID:4212443 -2.7.7.7 * orthopoxvirus vaccinia 0.633 0.633 1 * -2.7.7.7 * pyrococcus furiosus 0.07 0.07 1 PMID:8787781 -2.7.7.7 * saccharolobus solfataricus 20.0 20.0 1 PMID:3145018 -2.7.7.7 * saccharomyces cerevisiae 1.22 1.22 1 PMID:23160073 -2.7.7.7 * strongylocentrotus purpuratus 0.027 0.027 1 PMID:4859478 -2.7.7.7 * sulfolobus acidocaldarius 178.0 178.0 1 PMID:3927262 -2.7.7.7 * sulfophobococcus zilligii 0.0033 0.0033 1 * -2.7.7.7 * tequatrovirus t4 1.033 1.033 1 PMID:4605411 -2.7.7.7 * thermus aquaticus 0.5 0.5 1 * -2.7.7.7 * thermus caldophilus 28.0 28.0 1 PMID:8508785 -2.7.7.7 * thermus thermophilus 20.0 20.0 1 PMID:1320608 -2.7.7.72 * escherichia coli 280.0 173.55 2 PMID:328503 -2.7.7.74 * archaeoglobus fulgidus 62.9 62.9 1 PMID:21378188 -2.7.7.74 * rhodothermus marinus 59.8 59.8 1 * -2.7.7.8 * azotobacter vinelandii 39.6 39.6 1 PMID:14481058 -2.7.7.8 * bradyrhizobium japonicum 0.02 0.02 1 * -2.7.7.8 * cucumis sativus 34.08 34.08 1 PMID:16593547 -2.7.7.8 * escherichia coli 27.67 27.67 1 PMID:330538 -2.7.7.8 * geobacillus stearothermophilus 22.5 22.5 1 PMID:4615305 -2.7.7.8 * kitasatospora aureofaciens 35.8 35.8 1 PMID:1122294 -2.7.7.8 * nicotiana tabacum 0.0002 0.0002 1 PMID:4429350 -2.7.7.8 * nostoc sp. 2.0 2.0 1 * -2.7.7.8 * salinivibrio costicola 99.01 99.01 1 PMID:3970947 -2.7.7.8 * sinorhizobium meliloti 3.8 3.8 1 * -2.7.7.8 * synechococcus sp. 0.2 0.2 1 * -2.7.7.8 * thermus thermophilus 1.1 1.1 1 PMID:891551 -2.7.7.83 * homo sapiens 69.0 3.6075 10 PMID:11707391;PMID:9765219 -2.7.7.84 * sus scrofa 10.1 10.1 1 PMID:14636576 -2.7.7.89 * escherichia coli 0.015 0.015 1 PMID:4893578 -2.7.7.9 * acanthamoeba castellanii 15.8 15.8 1 PMID:4430676 -2.7.7.9 * arabidopsis thaliana 715.0 447.5 4 PMID:18395530 -2.7.7.9 * bifidobacterium bifidum 15.2 13.0 3 PMID:24014529;PMID:500588;PMID:718964 -2.7.7.9 * bos taurus 200.0 16.0 3 PMID:4731964;PMID:5062946 -2.7.7.9 * cucumis sativus 3.9 3.9 1 PMID:24276942 -2.7.7.9 * escherichia coli 4.76 4.76 1 PMID:8169209 -2.7.7.9 * felis catus 2.15 2.15 1 PMID:6099063 -2.7.7.9 * homo sapiens 200.0 200.0 1 * -2.7.7.9 * hordeum vulgare 1074.0 1074.0 1 PMID:19683599 -2.7.7.9 * leishmania major 1477.0 1477.0 1 PMID:17303565 -2.7.7.9 * mycobacterium tuberculosis 0.1005 0.1005 1 PMID:18621545 -2.7.7.9 * oryctolagus cuniculus 495.0 347.5 2 PMID:4436332 -2.7.7.9 * solanum tuberosum 1099.0 674.0 4 PMID:12231759;PMID:17996328;PMID:2558111 -2.7.7.9 * sorghum bicolor 1200.0 1200.0 1 PMID:5012314 -2.7.7.9 * streptomyces thermophilus 0.11 0.11 1 PMID:10919816 -2.7.7.9 * sulfurisphaera tokodaii 7.48 2.2 3 PMID:15598657;PMID:25567746 -2.7.7.97 * streptomyces antibioticus 0.795 0.39790000000000003 2 PMID:8385097 -2.7.7.97 * streptomyces anulatus 0.38 0.202 2 PMID:1318300 -2.7.7.97 * streptomyces lividans 1.18 0.5964999999999999 2 PMID:10212227 -2.7.8.1 * homo sapiens 0.0763 0.0763 1 PMID:17132865 -2.7.8.1 * rattus norvegicus 12.1 1.705 3 PMID:182489;PMID:2545264;PMID:3030437 -2.7.8.11 * bos taurus 0.002 0.002 1 * -2.7.8.11 * candida albicans 0.001 0.001 1 PMID:8740418 -2.7.8.11 * canis lupus familiaris 0.29 0.15999999999999998 2 PMID:6093865 -2.7.8.11 * homo sapiens 34.0 34.0 1 PMID:9370331 -2.7.8.11 * plasmodium falciparum 3.6e-05 2.95e-05 2 PMID:17223316 -2.7.8.11 * rattus norvegicus 2.8 1.233 5 PMID:18462;PMID:2539091;PMID:4367970;PMID:9370331 -2.7.8.11 * saccharomyces cerevisiae 0.8 0.40040000000000003 2 PMID:1323046;PMID:3005284;PMID:6300035 -2.7.8.12 * bacillus subtilis 0.074 0.074 1 PMID:12637499 -2.7.8.13 * bacillus subtilis 1.7 1.7 1 PMID:18672909 -2.7.8.13 * escherichia coli 0.000276 0.000276 1 PMID:8631795 -2.7.8.14 * staphylococcus aureus 0.0035 0.0035 1 PMID:4828314 -2.7.8.17 * bos taurus 0.12 0.12 1 PMID:8940155 -2.7.8.17 * homo sapiens 6.82 6.82 1 PMID:16507578 -2.7.8.17 * rattus norvegicus 0.000733 0.00036669000000000003 2 PMID:6094964;PMID:6288715 -2.7.8.2 * homo sapiens 0.00036 4.35e-05 8 PMID:17710109 -2.7.8.2 * phytophthora infestans 0.00323 0.00323 1 PMID:23275500 -2.7.8.2 * rattus norvegicus 0.13 0.13 1 PMID:8382767 -2.7.8.2 * sus scrofa 0.0132 0.0132 1 PMID:8274015 -2.7.8.22 * cavia porcellus 9e-05 9e-05 1 PMID:3447597 -2.7.8.26 * salmonella enterica subsp. enterica serovar typhimurium 0.008 0.008 1 PMID:10518530 -2.7.8.28 * methanocaldococcus jannaschii 0.36 0.36 1 PMID:11888293 -2.7.8.29 * cricetulus griseus 0.51 0.385 2 PMID:12912985 -2.7.8.29 * homo sapiens 1.0 1.0 1 PMID:19014349 -2.7.8.33 * thermotoga maritima 0.2895 0.2895 1 PMID:18723618 -2.7.8.39 * aeropyrum pernix 1867.0 1867.0 1 PMID:24269814 -2.7.8.39 * methanothermobacter thermautotrophicus 0.02 0.02 1 PMID:19740749 -2.7.8.39 * saccharolobus solfataricus 1783.0 1783.0 1 PMID:24269814 -2.7.8.4 * gallus gallus 0.0034 0.0034 1 PMID:5936240 -2.7.8.41 * rattus norvegicus 4.1e-06 1.734e-06 4 PMID:1659453;PMID:7564918 -2.7.8.41 * saccharomyces cerevisiae 0.000513 0.000513 1 PMID:7564918 -2.7.8.5 * bacillus licheniformis 0.36 0.36 1 PMID:175832 -2.7.8.5 * clostridium perfringens 0.03 0.03 1 PMID:6246064 -2.7.8.5 * cricetulus griseus 12.0 0.000197 5 PMID:11171073;PMID:18162584 -2.7.8.5 * escherichia coli 22.0 20.3 2 PMID:1323047 -2.7.8.5 * kluyveromyces lactis 0.0018 0.001535 2 PMID:18759116 -2.7.8.5 * schizosaccharomyces pombe 1.17 1.17 1 PMID:9468529 -2.7.8.7 * corynebacterium ammoniagenes 0.32 0.32 1 PMID:9346306 -2.7.8.7 * escherichia coli 0.32 0.16395 4 PMID:7559576;PMID:9211277 -2.7.8.8 * escherichia coli 39.0 7.86 7 PMID:1323044;PMID:187212;PMID:19072541 -2.7.9.1 * [clostridium] symbiosum 35.0 32.2 2 PMID:237180;PMID:6294456 -2.7.9.1 * acetobacter aceti 5.9 5.9 1 * -2.7.9.1 * entamoeba histolytica 12.0 12.0 1 PMID:9507062 -2.7.9.1 * komagataeibacter xylinus 0.88 0.88 1 PMID:237179 -2.7.9.1 * propionibacterium freudenreichii subsp. shermanii 2.1 2.1 1 PMID:237180 -2.7.9.1 * rhodospirillum rubrum 3.51 3.51 1 PMID:3003027 -2.7.9.1 * solanum lycopersicum 0.0006 0.0006 1 PMID:27450492 -2.7.9.1 * trypanosoma brucei 2.5 2.5 1 PMID:9653123 -2.7.9.1 * trypanosoma cruzi 0.2 0.10250000000000001 2 PMID:27003459 -2.7.9.1 * trypanosoma evansi 0.016 0.016 1 PMID:26968775 -2.7.9.1 * zea mays 4.5 2.055 6 PMID:10683263;PMID:27450492;PMID:4719122 -2.7.9.2 * escherichia coli 8.9 8.9 1 PMID:4319237 -2.7.9.2 * pyrococcus furiosus 14.9 7.4750000000000005 2 PMID:11133966 -2.7.9.2 * pyrococcus horikoshii 13.3 6.800000000000001 2 PMID:19784642 -2.7.9.3 * escherichia coli 29.0 29.0 1 PMID:9874769 -2.7.9.3 * haemophilus influenzae 16.0 16.0 1 PMID:9874769 -2.7.9.4 * arabidopsis thaliana 1.36 0.02 11 PMID:18024995;PMID:18419779 -2.7.9.4 * solanum tuberosum 6.19 1.01 9 PMID:16584202 -2.7.9.5 * arabidopsis thaliana 0.002 0.002 1 PMID:18419779 -2.8.1.1 * acinetobacter calcoaceticus 70.0 70.0 1 PMID:6931629 -2.8.1.1 * aquifex aeolicus 850.0 850.0 1 PMID:17697123 -2.8.1.1 * azotobacter vinelandii 550.0 440.0 3 PMID:10788632 -2.8.1.1 * bos indicus 1.25 0.318 8 PMID:11254178 -2.8.1.1 * bos taurus 816.0 47.8 20 PMID:11368014;PMID:1627606;PMID:17551834;PMID:6948991;PMID:8132546 -2.8.1.1 * camelus dromedarius 1.7 0.060000000000000005 14 PMID:11254178 -2.8.1.1 * canis lupus familiaris 0.32 0.065 6 * -2.8.1.1 * capra hircus 8.99 0.365 62 * -2.8.1.1 * cavia porcellus 6.0 6.0 1 PMID:6286464 -2.8.1.1 * chlorocebus aethiops 242.0 242.0 1 PMID:6586594 -2.8.1.1 * equus caballus 1.7 0.15 6 * -2.8.1.1 * escherichia coli 700.0 360.5 2 PMID:10735872;PMID:3553189 -2.8.1.1 * gallus gallus 0.426 0.214 7 PMID:11254178 -2.8.1.1 * homo sapiens 2.6 0.139 14 PMID:11788560;PMID:29348167 -2.8.1.1 * manihot esculenta 0.63 0.63 1 * -2.8.1.1 * mus musculus 1071.0 0.23 17 * -2.8.1.1 * oncorhynchus mykiss 818.0 818.0 1 PMID:8535164 -2.8.1.1 * ovis aries 16.3 0.24 17 PMID:11254178 -2.8.1.1 * pseudomonas aeruginosa 816.0 816.0 1 PMID:16307778 -2.8.1.1 * rattus norvegicus 600.0 2.27 43 PMID:1213990;PMID:6286464 -2.8.1.1 * rhodopseudomonas palustris 297.9 297.9 1 * -2.8.1.1 * trametes sanguinea 15.9 15.9 1 * -2.8.1.2 * bos taurus 1240.0 787.0 2 PMID:4370594;PMID:564663;PMID:6948992 -2.8.1.2 * escherichia coli 540.0 540.0 1 PMID:4550801 -2.8.1.2 * homo sapiens 2.3 2.05 2 PMID:32179647 -2.8.1.2 * rattus norvegicus 3793.0 128.135 6 PMID:170130;PMID:6026243;PMID:7608189;PMID:9749958 -2.8.1.3 * acinetobacter calcoaceticus 1670.0 1670.0 1 PMID:3480285 -2.8.1.3 * saccharomyces cerevisiae 62.0 62.0 1 PMID:383018 -2.8.1.4 * bacillus subtilis 0.00815 0.00815 1 PMID:4987417 -2.8.1.4 * rattus norvegicus 6.58e-05 3.476e-05 2 PMID:4601536;PMID:597293 -2.8.1.5 * phormidium uncinatum 789.0 789.0 1 * -2.8.1.7 * acidithiobacillus ferrooxidans 82500.0 0.11499999999999999 4 PMID:17660944 -2.8.1.7 * azotobacter vinelandii 0.142 0.09849999999999999 2 PMID:9812986 -2.8.1.7 * escherichia coli 0.008 0.0058 2 PMID:12941942;PMID:14978044 -2.8.1.7 * saccharomyces cerevisiae 45.7 22.856350000000003 2 PMID:15220327;PMID:22689995 -2.8.1.7 * streptomyces lividans 56.5 38.6 6 PMID:17469805 -2.8.1.7 * synechocystis sp. 21.0 5.3 4 PMID:11193410 -2.8.1.7 * trypanosoma brucei 2.5 0.7 6 PMID:19968861 -2.8.2.1 * canis lupus familiaris 0.0036 0.0026 2 PMID:6956338 -2.8.2.1 * euglena gracilis 0.205 0.205 1 PMID:8129730 -2.8.2.1 * homo sapiens 29.1 0.002085 48 PMID:10336855;PMID:10623578;PMID:12228221;PMID:12761191;PMID:17002600;PMID:17433394;PMID:17506995;PMID:17954528;PMID:2327787;PMID:26465778;PMID:26663444;PMID:26948952;PMID:27582324;PMID:3463246;PMID:3860259;PMID:9325148 -2.8.2.1 * rattus norvegicus 0.282 0.0199 5 PMID:16822482;PMID:6948989;PMID:8530477 -2.8.2.11 * homo sapiens 1.2 1.2 1 PMID:8830034 -2.8.2.11 * mus musculus 3.65e-07 1.25e-07 11 PMID:19582571 -2.8.2.14 * cavia porcellus 0.0216 0.0216 1 PMID:6956371 -2.8.2.14 * homo sapiens 0.02361 0.00354 11 PMID:21839837;PMID:3862362;PMID:6928376 -2.8.2.14 * mus musculus 1380.2 274.1 15 PMID:28442498;PMID:29685090 -2.8.2.14 * rattus norvegicus 0.0164 0.01065 2 PMID:23845;PMID:6948990 -2.8.2.15 * danio rerio 0.0916 0.0184 17 PMID:14726148;PMID:15781253 -2.8.2.15 * homo sapiens 0.133 0.0201 5 PMID:156557;PMID:17112228;PMID:2764897;PMID:6932974 -2.8.2.15 * mus musculus 0.9993 0.9599 3 PMID:20718863 -2.8.2.15 * rattus norvegicus 0.0035 0.0009044999999999999 4 PMID:3464463;PMID:6596951;PMID:737567 -2.8.2.17 * homo sapiens 5e-07 5e-07 1 PMID:18698629 -2.8.2.17 * mus musculus 0.000231 0.000231 1 PMID:9597547 -2.8.2.17 * rattus norvegicus 2.2e-07 2.2e-07 1 PMID:16495484 -2.8.2.18 * rattus norvegicus 0.016 0.012 3 PMID:485156;PMID:6936065;PMID:737567 -2.8.2.19 * rattus norvegicus 6.85e-06 6.85e-06 1 PMID:6575780 -2.8.2.2 * drosophila melanogaster 5.77e-05 5.77e-05 1 PMID:18157937 -2.8.2.2 * homo sapiens 0.15 0.0071 9 PMID:11377982;PMID:17347498;PMID:26663444 -2.8.2.2 * mus musculus 0.0004737 0.0002544 8 PMID:11594734 -2.8.2.2 * petromyzon marinus 0.002038 0.000231 3 PMID:14657197 -2.8.2.2 * rattus norvegicus 0.57 0.099 6 PMID:11527219;PMID:4129;PMID:6173569;PMID:6935986;PMID:8924618 -2.8.2.20 * bos taurus 0.0057 0.0057 1 PMID:2295314 -2.8.2.20 * homo sapiens 6.3 3.2e-06 3 PMID:17028309;PMID:9501187 -2.8.2.20 * rattus norvegicus 7.329 2.95 3 PMID:9015392;PMID:9501187;PMID:9522174 -2.8.2.21 * bos taurus 1.3e-05 1.3e-05 1 PMID:6222956 -2.8.2.21 * gallus gallus 3.3e-05 3.3e-05 1 PMID:11469798 -2.8.2.22 * agathobacter rectalis 147.0 147.0 1 PMID:11320417 -2.8.2.22 * eubacterium sp. 89.4 25.6 5 PMID:17202651;PMID:3460636;PMID:3465324;PMID:7982888 -2.8.2.22 * haemophilus sp. 6.67 6.67 1 PMID:8576095 -2.8.2.22 * klebsiella sp. 8.82 8.82 1 PMID:1491000 -2.8.2.24 * brassica juncea 3.29e-05 3.29e-05 1 * -2.8.2.24 * lepidium sativum 0.935 0.935 1 PMID:16667782 -2.8.2.25 * flaveria chlorifolia 0.00027 0.00027 1 PMID:16666908 -2.8.2.26 * flaveria chlorifolia 0.0025 0.0025 1 PMID:16666908 -2.8.2.27 * flaveria chlorifolia 0.002 0.002 1 PMID:16666908 -2.8.2.28 * arabidopsis thaliana 0.017 0.017 1 PMID:17095238 -2.8.2.28 * flaveria bidentis 0.00058 0.00048 2 PMID:16668120 -2.8.2.3 * cavia porcellus 0.05 0.05 1 PMID:3475273 -2.8.2.3 * rattus norvegicus 0.236 0.236 1 PMID:7820098 -2.8.2.31 * petromyzon marinus 2e-06 2e-06 1 PMID:14657197 -2.8.2.32 * danio rerio 0.02768 0.010110000000000001 6 PMID:28807679 -2.8.2.32 * heterodontus portusjacksoni 4.39e-08 2.75e-08 3 PMID:7749614 -2.8.2.32 * homo sapiens 0.00471 0.002525 2 PMID:28807679 -2.8.2.32 * trygonoptera sp. 2.6e-06 2.6e-06 1 * -2.8.2.32 * trygonorrhina fasciata 3.5e-06 3.5e-06 1 * -2.8.2.33 * homo sapiens 0.0022 0.0022 1 PMID:3082866 -2.8.2.34 * homo sapiens 0.018 0.018 1 PMID:1397553 -2.8.2.34 * mesocricetus auratus 6.2e-05 5e-06 5 PMID:533830 -2.8.2.34 * rattus norvegicus 0.023 5.6e-05 13 PMID:1293312;PMID:2435165;PMID:2754334;PMID:3456744;PMID:3464463 -2.8.2.38 * arabidopsis thaliana 0.0974 0.07505 4 PMID:28646214 -2.8.2.4 * bos taurus 0.01 0.01 1 PMID:4429698 -2.8.2.4 * cavia porcellus 0.0274 0.0274 1 PMID:2363709 -2.8.2.4 * homo sapiens 0.0455 0.000347 20 PMID:11478778;PMID:17306434;PMID:17954528;PMID:18379081 -2.8.2.5 * mus musculus 1e-05 1e-05 1 PMID:10722746 -2.8.2.5 * rattus norvegicus 6e-06 6e-06 1 PMID:9891016 -2.8.2.6 * penicillium chrysogenum 0.000825 0.000825 1 PMID:18095 -2.8.2.7 * gallus gallus 6.9e-06 6.9e-06 1 PMID:6022874 -2.8.2.8 * homo sapiens 231.0 231.0 1 PMID:9744796 -2.8.2.8 * rattus norvegicus 1.95 1.95 1 PMID:3422231 -2.8.2.9 * euglena gracilis 0.2053 0.2053 1 PMID:8129730 -2.8.2.9 * rattus norvegicus 0.8 0.54 5 PMID:5441369;PMID:6946725;PMID:6948989;PMID:9111223 -2.8.3.1 * anaerotignum propionicum 157.0 85.0 3 PMID:11784332;PMID:16454529;PMID:6586495 -2.8.3.10 * klebsiella aerogenes 25.0 17.05 2 PMID:336371 -2.8.3.13 * rattus norvegicus 0.248 0.13369999999999999 2 PMID:2597704;PMID:6946836 -2.8.3.14 * anaerocolumna aminovalerica 38.0 38.0 1 PMID:2085413 -2.8.3.15 * aromatoleum aromaticum 0.235 0.11499999999999999 8 PMID:27102732 -2.8.3.15 * thauera aromatica 320.0 167.5 2 PMID:10589736;PMID:11418570 -2.8.3.16 * oxalobacter formigenes 2.15 1.39 2 PMID:2361939 -2.8.3.18 * acetobacter aceti 0.17 0.0985 4 PMID:18502856 -2.8.3.18 * trichomonas vaginalis 0.007 0.007 1 PMID:18024431 -2.8.3.18 * trypanosoma brucei 0.058 0.058 1 PMID:15326192 -2.8.3.19 * escherichia coli 9.5 9.5 1 PMID:23935849 -2.8.3.20 * chloroflexus aurantiacus 17.5 17.5 1 PMID:16952935 -2.8.3.21 * escherichia coli 187.8 187.8 1 PMID:11551212 -2.8.3.21 * proteus sp. (in: enterobacteria) 556.3 556.3 1 PMID:15731894 -2.8.3.22 * chloroflexus aurantiacus 7.5 7.5 1 PMID:16547052 -2.8.3.26 * haloarcula hispanica 16.9 16.9 1 PMID:28932214 -2.8.3.27 * cutibacterium granulosum 0.0917 0.0917 1 PMID:33931420 -2.8.3.28 * aromatoleum aromaticum 0.235 0.11499999999999999 8 PMID:27102732 -2.8.3.5 * helicobacter pylori 1.164 1.164 1 PMID:9325289 -2.8.3.5 * homo sapiens 0.0038 0.0005 3 PMID:11757586;PMID:19296078 -2.8.3.5 * ovis aries 200.0 190.0 2 PMID:6577858;PMID:708372 -2.8.3.5 * rattus norvegicus 161.0 19.5 7 PMID:1111526;PMID:4415977;PMID:6594997;PMID:6950030 -2.8.3.5 * sus scrofa 280.0 25.2 7 PMID:11327867;PMID:17718512;PMID:4763316;PMID:6945874;PMID:943396 -2.8.3.6 * acinetobacter calcoaceticus 24.2 24.2 1 PMID:6780551 -2.8.3.6 * pseudomonas knackmussii 23.9 14.25 2 PMID:11741862;PMID:11741863 -2.8.3.6 * pseudomonas putida 21.3 21.3 1 PMID:6780551 -2.8.3.8 * coprococcus sp. 118.4 64.60000000000001 2 PMID:12324374 -2.8.3.8 * escherichia coli 0.1 0.1 1 PMID:4884054 -2.8.3.8 * faecalibacterium prausnitzii 19.0 18.82 2 PMID:12324374 -2.8.3.8 * roseburia intestinalis 25.5 9.07 6 PMID:12324374 -2.8.3.8 * roseburia sp. 38.95 12.34 4 PMID:12324374 -2.8.3.9 * clostridium sp. 329.0 329.0 1 PMID:624727 -2.8.3.9 * escherichia coli 160.0 138.5 2 PMID:1103739 -2.8.4.1 * methanobacterium bryantii 0.00094 0.0007375 2 PMID:6766457 -2.8.4.1 * methanobacterium formicicum 0.000935 0.000935 1 PMID:6766457 -2.8.4.1 * methanobrevibacter ruminantium 0.006 0.006 1 PMID:25483006 -2.8.4.1 * methanosarcina barkeri 0.00046 0.00046 1 PMID:6766457 -2.8.4.1 * methanosarcina thermophila 0.224 0.224 1 PMID:2013570 -2.8.4.1 * methanospirillum hungatei 0.001135 0.001135 1 PMID:6766457 -2.8.4.1 * methanothermobacter thermautotrophicus 100.0 2.5 15 PMID:1332856;PMID:1657649;PMID:2504147;PMID:2506016;PMID:3137210;PMID:3350018;PMID:6766457;PMID:8223602;PMID:9030728 -2.8.4.1 * methanothrix soehngenii 0.051 0.051 1 * -3.1.1.1 * acinetobacter lwoffii 1440.0 1440.0 1 PMID:12000989 -3.1.1.1 * arabidopsis thaliana 7902.0 3859.0 10 PMID:17270225;PMID:17519238 -3.1.1.1 * archaeoglobus fulgidus 3000.0 168.0 3 PMID:10620337 -3.1.1.1 * arthrobacter globiformis 52.8 52.8 1 * -3.1.1.1 * aspergillus nidulans 5.62 2.8665000000000003 2 PMID:18224318 -3.1.1.1 * aspergillus nomiae 135.0 135.0 1 PMID:12799010 -3.1.1.1 * bacillus subtilis 1735.0 0.36000000000000004 14 PMID:16269247;PMID:16621096 -3.1.1.1 * bacillus velezensis 41.87 21.27 5 PMID:31761671 -3.1.1.1 * bombyx mori 429.5 429.5 1 * -3.1.1.1 * canis lupus familiaris 38.0 38.0 1 PMID:3401497 -3.1.1.1 * danio rerio 16.0 10.0 2 PMID:16112210 -3.1.1.1 * enterobacter cloacae 0.0027 0.0019 5 PMID:12556461 -3.1.1.1 * equus caballus 1.92 1.92 1 PMID:3196030 -3.1.1.1 * escherichia coli 38.9 10.55 6 PMID:12732651 -3.1.1.1 * geobacillus stearothermophilus 1543.0 772.516 2 PMID:7576531 -3.1.1.1 * geobacillus thermodenitrificans 2.58 2.58 1 PMID:20587647 -3.1.1.1 * geobacillus thermoleovorans 1375.7 1375.7 1 PMID:26603441 -3.1.1.1 * haloarcula marismortui 590.0 590.0 1 PMID:19303051 -3.1.1.1 * homo sapiens 610.0 3.6149999999999998 42 PMID:10497064;PMID:10728672;PMID:1248462;PMID:15100172;PMID:16387282;PMID:21540359;PMID:25462813;PMID:28532270;PMID:30095924;PMID:3401497;PMID:4216303;PMID:718955 -3.1.1.1 * klebsiella sp. 573.0 67.0 13 PMID:16448191 -3.1.1.1 * lacticaseibacillus casei 48.8 48.8 1 PMID:12741535 -3.1.1.1 * lactobacillus delbrueckii subsp. lactis 51.0 44.0 2 PMID:12741535 -3.1.1.1 * microbacterium sp. 26.0 26.0 1 PMID:11814667 -3.1.1.1 * mus musculus 394.8 0.061 19 PMID:15123619;PMID:6772441;PMID:6788549;PMID:7160378 -3.1.1.1 * mycobacterium tuberculosis 1618.0 866.5 6 PMID:15373841 -3.1.1.1 * niallia circulans 88.2 88.2 1 PMID:10968629 -3.1.1.1 * oryctolagus cuniculus 374.0 106.205 4 PMID:16387282;PMID:3597342 -3.1.1.1 * oryzaephilus surinamensis 2.0 1.385 2 * -3.1.1.1 * phaseolus vulgaris 0.843 0.843 1 PMID:29604085 -3.1.1.1 * pseudomonas aeruginosa 7310.0 7310.0 1 PMID:15717224 -3.1.1.1 * pseudomonas aeruginosa pao1 7310.0 7310.0 1 PMID:15717224 -3.1.1.1 * pseudomonas fluorescens 27000.0 2598.0 5 PMID:12729729 -3.1.1.1 * pseudomonas sp. 1110.0 62.0 5 PMID:12880765;PMID:7764864 -3.1.1.1 * pseudomonas synxantha 2226.0 1119.8 2 PMID:28615636 -3.1.1.1 * pyrobaculum calidifontis 4050.0 747.0 11 PMID:12147492 -3.1.1.1 * rattus norvegicus 437.0 41.9 11 PMID:12230550;PMID:15767260;PMID:3401497;PMID:4828316;PMID:7074137;PMID:738990;PMID:8105781 -3.1.1.1 * reticulitermes flavipes 0.84 0.505 6 PMID:11267909 -3.1.1.1 * rhizobium viscosum 55.4 55.4 1 * -3.1.1.1 * saccharolobus solfataricus 3975.0 1392.0 5 PMID:15564667;PMID:15581894;PMID:16574328 -3.1.1.1 * streptococcus equi 815.0 68.0 7 PMID:19054107 -3.1.1.1 * streptomyces lividans 47.9 11.100000000000001 6 PMID:33515353 -3.1.1.1 * sulfolobus acidocaldarius 158.0 158.0 1 PMID:3128284 -3.1.1.1 * sulfurisphaera tokodaii 3542.0 56.0 9 PMID:15212797 -3.1.1.1 * sus scrofa 600.0 46.002645 4 PMID:11828491;PMID:16960735;PMID:18273909 -3.1.1.1 * thalassobacillus sp. 2046.0 1149.0 2 * -3.1.1.1 * thermus thermophilus 317.2 317.2 1 * -3.1.1.1 * tribolium castaneum 0.124 0.124 1 PMID:12213253 -3.1.1.1 * trichosporon sp. 831.0 831.0 1 * -3.1.1.1 * uncultured bacterium 488.9 12.96 13 PMID:21908637;PMID:29453256;PMID:33478024 -3.1.1.1 * unidentified 513.6 387.5 11 PMID:16672512 -3.1.1.1 * unidentified soil organism 54.7 22.9 11 PMID:16672512 -3.1.1.1 * xeropicta derbentina 1095.0 437.0 3 PMID:18775593 -3.1.1.10 * oryctolagus cuniculus 0.706 0.706 1 PMID:4435736 -3.1.1.101 * bacterium hr29 285.6 86.9 7 PMID:33375975 -3.1.1.101 * piscinibacter sakaiensis 163.7 52.5 5 PMID:33375975 -3.1.1.101 * thermomonospora curvata 88.8 85.94999999999999 2 PMID:254050803 -3.1.1.11 * acetivibrio thermocellus 18.1 14.1 5 PMID:28332030 -3.1.1.11 * actinidia chinensis 2450.0 2200.0 2 PMID:15675822 -3.1.1.11 * arabidopsis thaliana 13.0 11.98 3 PMID:18936961;PMID:33029918 -3.1.1.11 * aspergillus aculeatus 7.59 4.925 2 * -3.1.1.11 * aspergillus flavus 194.0 99.85 2 PMID:24766423 -3.1.1.11 * aspergillus niger 342.0 9.67 3 PMID:22806239;PMID:30042002 -3.1.1.11 * aspergillus oryzae 7601.0 27.5 12 PMID:34489047 -3.1.1.11 * aspergillus pseudoglaucus 6.5 3.66 2 * -3.1.1.11 * capsicum annuum 242.5 242.5 1 PMID:15373415 -3.1.1.11 * carica papaya 2363.1 2363.1 1 PMID:30035386 -3.1.1.11 * citrus bergamia 2333.0 2275.0 4 PMID:26047267 -3.1.1.11 * citrus sinensis 963.0 4.220000000000001 8 PMID:12926897;PMID:24328246 -3.1.1.11 * citrus x paradisi 892.0 892.0 1 PMID:10956097 -3.1.1.11 * cucumis melo 152.0 152.0 1 PMID:32478425 -3.1.1.11 * dickeya chrysanthemi 1.19 1.19 1 * -3.1.1.11 * diospyros kaki 1350.0 1350.0 1 PMID:15675822 -3.1.1.11 * ficus pumila var. awkeotsang 283.0 283.0 1 PMID:11982420 -3.1.1.11 * fragaria x ananassa 176.0 176.0 1 PMID:11992533 -3.1.1.11 * glycine max 115.0 115.0 1 PMID:3948878 -3.1.1.11 * malpighia glabra 206.0 136.0 2 * -3.1.1.11 * paenibacillus xylanexedens 39.38 39.38 1 PMID:33232801 -3.1.1.11 * penicillium oxalicum 68.6 68.6 1 PMID:24584459 -3.1.1.11 * prunus armeniaca 2702.0 70.92 3 * -3.1.1.11 * psidium guajava 15.67 15.67 1 * -3.1.1.11 * solanum lycopersicum 834.0 26.96 5 PMID:12153307;PMID:12926897;PMID:17927134 -3.1.1.111 * rattus norvegicus 1800.0 2.95 4 PMID:11395520;PMID:12069807;PMID:8999922 -3.1.1.113 * pseudomonas putida 42.0 24.0 4 * -3.1.1.113 * pseudomonas veronii 288.0 147.5 6 PMID:17351032 -3.1.1.117 * apiospora arundinis 1.02 1.02 1 PMID:29051046 -3.1.1.117 * ascobolus immersus 13.5 13.5 1 PMID:29051046 -3.1.1.117 * botryosphaeria dothidea 4.6 4.6 1 PMID:29051046 -3.1.1.117 * dichomitus squalens 69.5 36.13 2 PMID:29051046 -3.1.1.117 * hypholoma sublateritium 140.01 140.01 1 PMID:29051046 -3.1.1.117 * parastagonospora nodorum 4.6 4.6 1 PMID:29051046 -3.1.1.117 * penicillium rubens 9.72 9.72 1 PMID:29051046 -3.1.1.117 * phanerochaete carnosa 270.0 270.0 1 PMID:29051046 -3.1.1.117 * piromyces sp. e2 31.2 31.2 1 PMID:29051046 -3.1.1.117 * podospora anserina 3.6 2.88 2 PMID:29051046 -3.1.1.117 * schizophyllum commune 1000.4 40.9 7 PMID:16876163;PMID:17440709;PMID:29051046 -3.1.1.117 * serendipita indica 4.02 4.02 1 PMID:29051046 -3.1.1.117 * stereum hirsutum 19.98 19.98 1 PMID:29051046 -3.1.1.117 * thermothelomyces thermophilus 1.9 1.9 1 PMID:29051046 -3.1.1.117 * thermothielavioides terrestris 43.95 28.21 2 PMID:30762074 -3.1.1.117 * trichoderma reesei 19.98 19.98 1 PMID:29051046 -3.1.1.118 * bos taurus 2.95 1.475105 2 PMID:8631903 -3.1.1.13 * acinetobacter sp. 11.9 6.25 2 PMID:20473956 -3.1.1.13 * bos taurus 51.6 0.785 8 PMID:10220579;PMID:6849967;PMID:7297682;PMID:7370289;PMID:8468334 -3.1.1.13 * burkholderia cepacia 5.1 5.1 1 PMID:16463077 -3.1.1.13 * burkholderia stabilis 135.0 135.0 1 PMID:33279561 -3.1.1.13 * chromobacterium viscosum 7.8 4.6 5 PMID:14741769 -3.1.1.13 * diutina rugosa 11.0 6.9 5 PMID:14741769 -3.1.1.13 * fusarium oxysporum 9.01 9.01 1 PMID:19426 -3.1.1.13 * homo sapiens 234.6 0.066 9 PMID:10220579;PMID:1627617;PMID:4066668 -3.1.1.13 * ophiostoma piceae 1336.0 319.0 7 PMID:12479402;PMID:19281875 -3.1.1.13 * oryctolagus cuniculus 0.001 0.001 1 PMID:6848493 -3.1.1.13 * pseudomonas aeruginosa 8.5 8.5 1 PMID:12506971 -3.1.1.13 * pseudomonas sp. 3.1 0.18 5 PMID:14741769 -3.1.1.13 * rattus norvegicus 0.028 0.022 2 PMID:11861500 -3.1.1.13 * rattus sp. 43.5 0.05 11 PMID:6768394;PMID:6849967;PMID:7026545;PMID:7278675;PMID:7357021;PMID:7370289;PMID:8463327;PMID:8477841 -3.1.1.13 * saccharomyces cerevisiae 0.003 0.003 1 PMID:7026545;PMID:8477841 -3.1.1.13 * streptomyces avermitilis 33.0 33.0 1 PMID:17161031 -3.1.1.13 * streptomyces griseus 32.5 32.5 1 PMID:17161031 -3.1.1.13 * streptomyces sp. 78.8 11.8 9 PMID:16503286 -3.1.1.13 * sus scrofa 333.0 19.5 11 PMID:12831;PMID:3828371;PMID:6639954 -3.1.1.13 * trichoderma sp. 31.1 15.604000000000001 2 PMID:18499049 -3.1.1.14 * auxenochlorella protothecoides 0.96 0.96 1 PMID:3702739;PMID:7446992 -3.1.1.14 * brassica oleracea 10.9 7.975 4 PMID:20681655;PMID:25105918 -3.1.1.14 * citrus unshiu 2.0 2.0 1 * -3.1.1.14 * crocosphaera subtropica atcc 51142 75.6 11.15 3 PMID:25828734 -3.1.1.14 * oxynema acuminatum 786.0 786.0 1 PMID:33430874 -3.1.1.14 * phaeodactylum tricornutum 322.0 134.4 3 PMID:18025587 -3.1.1.14 * phaseolus vulgaris 41.3 35.55 3 PMID:10866364;PMID:24414364 -3.1.1.14 * prunus cerasus 14.75 9.52 3 PMID:23894730 -3.1.1.14 * prunus domestica 19.47 16.92 3 PMID:23894730 -3.1.1.14 * prunus padus 7.42 5.53 3 PMID:23894730 -3.1.1.14 * secale cereale 0.48 0.48 1 PMID:6819291 -3.1.1.14 * solanum lycopersicum 31.0 31.0 3 PMID:36233017 -3.1.1.14 * triticum aestivum 15.0 15.0 1 PMID:15913540 -3.1.1.15 * azospirillum brasilense 0.013 0.013 1 PMID:6798025 -3.1.1.17 * bos taurus 1001.0 1001.0 1 PMID:35106 -3.1.1.17 * euglena gracilis 217.0 20.1 11 PMID:18782759 -3.1.1.17 * gluconobacter oxydans 2.5 1.29 2 PMID:19129636 -3.1.1.17 * rhodotorula mucilaginosa 175.3 175.3 1 PMID:18576080 -3.1.1.17 * saccharomyces cerevisiae 2.0 2.0 1 PMID:14353869 -3.1.1.17 * sus scrofa 1040.0 1040.0 1 PMID:718684 -3.1.1.17 * zymomonas mobilis subsp. mobilis 1894.0 1894.0 1 PMID:28341886 -3.1.1.2 * alopecurus myosuroides 0.04 0.00273 6 * -3.1.1.2 * avena fatua 0.03 0.003745 4 * -3.1.1.2 * bos taurus 40.0 40.0 1 PMID:175783 -3.1.1.2 * cavia porcellus 155.6 155.3 2 PMID:5047702 -3.1.1.2 * diabrotica virgifera virgifera 42.4 42.4 1 * -3.1.1.2 * gluconobacter oxydans 214.0 214.0 1 PMID:23003572 -3.1.1.2 * homo sapiens 1120.0 12.5 26 PMID:15772423;PMID:16139510;PMID:1673382;PMID:18624774;PMID:18711144;PMID:19103263;PMID:19679115;PMID:21040699;PMID:21123122 -3.1.1.2 * lactobacillus helveticus 623.0 554.5 2 PMID:10792515 -3.1.1.2 * oryctolagus cuniculus 3.5 3.5 1 PMID:21040699 -3.1.1.2 * saccharococcus caldoxylosilyticus 0.423 0.2135 2 * -3.1.1.2 * saccharolobus solfataricus 5580.0 2793.25 2 PMID:18931117 -3.1.1.2 * saccharomyces cerevisiae 3.81 3.81 1 * -3.1.1.2 * sinorhizobium meliloti 1021 35.0 35.0 1 PMID:20060410 -3.1.1.2 * streptomyces olivochromogenes 0.41 0.41 1 * -3.1.1.2 * triticum aestivum 170.7 0.19 9 * -3.1.1.20 * [candida] sp. 92.0 92.0 1 * -3.1.1.20 * aspergillus awamori 9550.0 1625.5 4 PMID:19844665;PMID:21030825 -3.1.1.20 * aspergillus ficuum 250.0 125.925 2 * -3.1.1.20 * aspergillus flavus 135.0 135.0 1 * -3.1.1.20 * aspergillus foetidus 88.3 61.0 2 * -3.1.1.20 * aspergillus heteromorphus 22.85 11.7125 2 * -3.1.1.20 * aspergillus nidulans 1.91 0.9704999999999999 2 * -3.1.1.20 * aspergillus niger 2917.0 40.7 17 PMID:14523126;PMID:14625895;PMID:14683525;PMID:21503777;PMID:25572938;PMID:29162409 -3.1.1.20 * aspergillus oryzae 2453.9 75.1 4 PMID:27373426 -3.1.1.20 * aureobasidium melanogenum 941.4 713.45 6 PMID:35211468 -3.1.1.20 * bacillus pumilus 12.8 12.8 1 PMID:32531366 -3.1.1.20 * cryphonectria parasitica 170.0 170.0 1 * -3.1.1.20 * enterobacter sp. 13.63 6.857 2 * -3.1.1.20 * geotrichum cucujoidarum 166.4 166.4 1 * -3.1.1.20 * herbaspirillum camelliae 58.3 38.75 2 PMID:34641872 -3.1.1.20 * hyalopus sp. 6.3 4.5 2 PMID:19590154 -3.1.1.20 * hypocreales sp. 82.2 72.0 2 PMID:17786433 -3.1.1.20 * kluyveromyces marxianus 1026.12 1026.12 1 PMID:29055707 -3.1.1.20 * lactiplantibacillus pentosus 68.0 68.0 1 PMID:32334591 -3.1.1.20 * lactiplantibacillus plantarum 84.34 20.0 3 PMID:18653299;PMID:20438129 -3.1.1.20 * paecilomyces variotii 49330.0 24667.8 2 PMID:16133325 -3.1.1.20 * penicillium chrysogenum 86.0 86.0 1 PMID:16346377 -3.1.1.20 * quercus robur 0.1602 0.1602 1 * -3.1.1.20 * rhodotorula diobovata 872.0 698.7 6 PMID:33143376 -3.1.1.20 * rhodotorula glutinis 3.33 3.33 1 * -3.1.1.20 * selenomonas ruminantium 6.8 6.8 1 PMID:16887543 -3.1.1.20 * staphylococcus lugdunensis 716.0 716.0 1 PMID:27704471 -3.1.1.20 * talaromyces variabilis 2055.0 1035.135 2 PMID:17570660 -3.1.1.20 * talaromyces verruculosus 13.29 13.29 1 * -3.1.1.20 * trametes elegans 6.49 3.4 2 * -3.1.1.22 * alcaligenes faecalis 41.2 41.2 1 PMID:6626560 -3.1.1.22 * paracoccus denitrificans 14.1 0.67 3 PMID:11814660;PMID:24271169 -3.1.1.23 * arabidopsis thaliana 23.93 0.355 18 PMID:26932457 -3.1.1.23 * bacillus sp. (in: firmicutes) 121.1 121.1 1 PMID:10731713 -3.1.1.23 * bacillus subtilis 200.0 200.0 1 PMID:11029590 -3.1.1.23 * mortierella alliacea 179.0 104.0 2 PMID:20932946 -3.1.1.23 * mus musculus 360.0 360.0 1 PMID:10733881 -3.1.1.23 * mycobacterium tuberculosis 290.0 290.0 1 PMID:17784850 -3.1.1.23 * mycolicibacterium smegmatis 143.0 111.5 2 PMID:20601476 -3.1.1.23 * pseudomonas sp. 109.0 109.0 1 PMID:16232941 -3.1.1.23 * rattus norvegicus 350.0 2.04 5 PMID:12223468;PMID:15013854;PMID:15492019 -3.1.1.24 * acinetobacter calcoaceticus 580.0 500.0 3 PMID:1158871;PMID:7391023 -3.1.1.24 * pseudomonas putida 717.0 717.0 1 PMID:5916392 -3.1.1.24 * rhizobium leguminosarum 0.171 0.171 1 * -3.1.1.25 * fusarium proliferatum 341.2 170.6076 2 PMID:17530243;PMID:19876606 -3.1.1.25 * homo sapiens 671.0 27.6 58 PMID:15772423;PMID:16139510 -3.1.1.25 * sulfolobus acidocaldarius 549.0 549.0 1 PMID:23174457 -3.1.1.26 * beta vulgaris 0.07 0.07 1 PMID:3595613 -3.1.1.26 * brassica napus 0.07 0.07 1 PMID:3595613 -3.1.1.26 * brassica oleracea 0.07 0.07 1 PMID:3595613 -3.1.1.26 * capsicum annuum 0.64 0.64 1 PMID:3595613 -3.1.1.26 * cavia porcellus 5420.0 4271.0 4 PMID:20083229 -3.1.1.26 * dahlia pinnata 0.96 0.96 1 PMID:3595613 -3.1.1.26 * fusarium vanettenii 4658.0 4221.5 2 * -3.1.1.26 * gracilaria vermiculophylla 0.00367 0.0019320000000000001 2 * -3.1.1.26 * homo sapiens 2976.0 317.0 9 PMID:18702514;PMID:20083229 -3.1.1.26 * lathyrus oleraceus 0.67 0.4 2 PMID:3595613 -3.1.1.26 * lathyrus oleraceus var. arvensis 0.33 0.23 2 PMID:3595613 -3.1.1.26 * lupinus angustifolius 1.25 0.98 2 PMID:3595613 -3.1.1.26 * medicago x varia 0.32 0.32 1 PMID:3595613 -3.1.1.26 * nicotiana tabacum 1.2 1.2 1 PMID:3595613 -3.1.1.26 * oryza sativa 3.75 3.75 1 * -3.1.1.26 * parachlorella kessleri 143.0 143.0 1 PMID:29299622 -3.1.1.26 * phaseolus coccineus 1.32 1.32 1 PMID:3595613 -3.1.1.26 * phaseolus vulgaris 4.655 3.0 3 * -3.1.1.26 * solanum habrochaites 0.82 0.82 1 PMID:3595613 -3.1.1.26 * solanum lycopersicum 2.5 1.8199999999999998 2 PMID:3595613 -3.1.1.26 * solanum peruvianum 0.31 0.31 1 PMID:3595613 -3.1.1.26 * spinacia oleracea 0.02 0.02 1 PMID:3595613 -3.1.1.26 * thermomyces dupontii 40500.0 9800.0 3 PMID:29859246 -3.1.1.26 * vicia faba 2.8 2.03 2 PMID:3595613 -3.1.1.26 * vigna unguiculata 0.0117 0.000625 4 PMID:7948009 -3.1.1.26 * zea mays 1.5 1.085 2 PMID:3595613 -3.1.1.27 * pseudomonas sp. 35.2 35.2 1 PMID:3771565 -3.1.1.29 * artemia sp. 0.0149 0.0149 1 * -3.1.1.29 * escherichia coli 30.0 15.075 2 PMID:12799450 -3.1.1.29 * fusarium culmorum 0.0051 0.0051 1 * -3.1.1.29 * saccharolobus solfataricus 31.8 4.14 3 PMID:12799450 -3.1.1.29 * staphylococcus aureus 0.07 0.07 1 PMID:11812233 -3.1.1.3 * acinetobacter baylyi 123.0 64.31 2 PMID:20177822 -3.1.1.3 * acinetobacter sp. 412.0 88.8 3 PMID:12444965;PMID:18633735 -3.1.1.3 * amycolatopsis mediterranei 781.6 391.78000000000003 2 PMID:21145735 -3.1.1.3 * arabidopsis thaliana 45.0 45.0 1 PMID:16226259 -3.1.1.3 * aspergillus carneus 502.0 502.0 1 * -3.1.1.3 * aspergillus fumigatus 1000.0 559.0 2 PMID:21744116 -3.1.1.3 * aspergillus nidulans 355.7 355.7 1 PMID:10637060 -3.1.1.3 * aspergillus niger 729.0 468.6 2 PMID:10907784 -3.1.1.3 * aureobasidium pullulans 88.6 11.735 6 PMID:18340544 -3.1.1.3 * bacillus cereus 632.0 218.5 3 * -3.1.1.3 * bacillus licheniformis 192.98 96.86 2 PMID:33548313 -3.1.1.3 * bacillus pumilus 138.0 138.0 1 PMID:12117564 -3.1.1.3 * bacillus safensis 13.71 8.485 2 * -3.1.1.3 * bacillus sp. (in: firmicutes) 1046.0 428.1 3 PMID:10839198;PMID:20127521 -3.1.1.3 * blastobotrys adeninivorans 367.0 367.0 1 PMID:15942926 -3.1.1.3 * bos taurus 68.0 68.0 1 PMID:3987686 -3.1.1.3 * burkholderia cepacia 8830.0 2960.0 3 PMID:18052929;PMID:18725331 -3.1.1.3 * burkholderia gladioli 443.9 270.505 2 PMID:31353877 -3.1.1.3 * burkholderia multivorans 68.4 68.4 1 PMID:15711795 -3.1.1.3 * burkholderia sp. 3294.0 1677.71 2 * -3.1.1.3 * burkholderia stabilis 135.0 135.0 1 PMID:33279561 -3.1.1.3 * candida parapsilosis 80.0 80.0 1 PMID:11895444 -3.1.1.3 * carica papaya 40.9 9.1 7 * -3.1.1.3 * cephaloleia presignis 13.26 13.26 1 PMID:10814595 -3.1.1.3 * clostridium tetanomorphum 900.0 900.0 1 * -3.1.1.3 * diutina rugosa 7200.0 75.05 12 PMID:11457462;PMID:16448188;PMID:16881684;PMID:18850711 -3.1.1.3 * ectopseudomonas mendocina 0.28 0.28 1 PMID:12614891 -3.1.1.3 * enterobacter cloacae 21264.3 10780.045 2 PMID:36018558 -3.1.1.3 * equus caballus 8000.0 3000.0 5 PMID:17961181 -3.1.1.3 * fagopyrum esculentum 0.86 0.5449999999999999 4 PMID:15563227 -3.1.1.3 * fusarium annulatum 3500.0 1776.5 2 PMID:37205651 -3.1.1.3 * fusarium solani 12.4 7.800000000000001 2 PMID:16114894 -3.1.1.3 * gallus gallus 9000.0 9000.0 1 PMID:16780787 -3.1.1.3 * geobacillus sp. 2259.0 1207.05 2 PMID:21531550 -3.1.1.3 * geobacillus stearothermophilus 4788.0 811.0 5 PMID:10737182;PMID:11483000;PMID:33766593 -3.1.1.3 * geobacillus thermocatenulatus 23000.0 23000.0 1 PMID:12651113 -3.1.1.3 * geobacillus thermoleovorans 3586.0 292.0 3 * -3.1.1.3 * geotrichum marinum 773.0 773.0 1 PMID:15233404 -3.1.1.3 * heyndrickxia coagulans 4.8 3.3899999999999997 2 PMID:15802219;PMID:16290008 -3.1.1.3 * homarus americanus 500.0 500.0 1 PMID:17395356 -3.1.1.3 * homo sapiens 8000.0 51.1 11 PMID:11040182;PMID:16431912;PMID:17401110;PMID:641046;PMID:9631512 -3.1.1.3 * hyalomma dromedarii 0.063 0.063 1 * -3.1.1.3 * liza parsia 32.5 20.45 2 * -3.1.1.3 * locusta migratoria 0.035 0.035 1 PMID:15804579 -3.1.1.3 * macruronus novaezelandiae 4.8 4.8 1 PMID:20143156 -3.1.1.3 * malassezia globosa 87.1 87.1 1 PMID:36553811 -3.1.1.3 * meleagris gallopavo 9500.0 5300.0 3 PMID:21272342 -3.1.1.3 * micrococcus sp. 239.5 239.5 1 * -3.1.1.3 * moesziomyces antarcticus 2033.0 2033.0 1 PMID:16575565 -3.1.1.3 * mycobacterium tuberculosis 0.041 0.02051 2 PMID:16354661 -3.1.1.3 * oncorhynchus tshawytscha 4.8 2.58 2 PMID:20143156 -3.1.1.3 * oryctolagus cuniculus 1150.0 683.0 2 PMID:3382677;PMID:6520114 -3.1.1.3 * oryza sativa 998.0 146.39 4 PMID:11743116;PMID:23202292 -3.1.1.3 * pachnoda sinuata flaviventris 0.057 0.057 1 PMID:15804579 -3.1.1.3 * penaeus vannamei 922.2 149.35 8 PMID:20965269 -3.1.1.3 * penicillium aurantiogriseum 94.0 60.5 6 * -3.1.1.3 * penicillium candidum 13900.0 13900.0 1 PMID:11337984 -3.1.1.3 * penicillium crustosum 10000.0 5080.0 2 PMID:36233221 -3.1.1.3 * penicillium expansum 85.94 85.94 1 PMID:18025580 -3.1.1.3 * periplaneta americana 0.005 0.005 1 PMID:15804579 -3.1.1.3 * priestia megaterium 414.0 414.0 1 PMID:15812860 -3.1.1.3 * pseudoalteromonas haloplanktis 0.95 0.5145 2 PMID:18437283 -3.1.1.3 * pseudomonas aeruginosa 19280.0 16.630000000000003 14 PMID:1539972;PMID:16450840;PMID:17027868;PMID:36399307 -3.1.1.3 * pseudomonas fluorescens 9854.0 4671.085 4 PMID:15596368;PMID:16233513;PMID:37240270 -3.1.1.3 * pseudomonas plecoglossicida 1181.3 654.85 2 PMID:35974269 -3.1.1.3 * pseudomonas sp. 3600.0 91.0 16 PMID:10825531;PMID:18987131 -3.1.1.3 * psychrobacter sp. 1084.0 1084.0 1 PMID:18051271 -3.1.1.3 * rhizomucor miehei 0.141 0.141 1 * -3.1.1.3 * rhizopus arrhizus 3500.0 2500.0 3 PMID:16842350 -3.1.1.3 * rhizopus homothallicus 10700.0 9650.0 2 PMID:17652784 -3.1.1.3 * rhizopus microsporus var. chinensis 305.0 30.15 4 PMID:18809324 -3.1.1.3 * ricinus communis 0.0242 0.0073 7 PMID:15322116 -3.1.1.3 * saccharolobus solfataricus 2108.0 2108.0 1 * -3.1.1.3 * saccharomyces cerevisiae 12.3 6.1855 2 PMID:12682047 -3.1.1.3 * scorpio maurus 5023.0 5023.0 1 PMID:16154275 -3.1.1.3 * serratia marcescens 497.0 74.2 6 PMID:18051356;PMID:20574813 -3.1.1.3 * serratia sp. w3 3530.0 3063.5 2 * -3.1.1.3 * sphingobacterium sp. ab3 2116.0 1088.75 2 PMID:36314920 -3.1.1.3 * staphylococcus caprae 502.76 252.135 2 PMID:33327795 -3.1.1.3 * staphylococcus simulans 1100.0 1100.0 1 PMID:11698108 -3.1.1.3 * staphylococcus warneri 123.0 70.0 4 PMID:11341932 -3.1.1.3 * staphylococcus xylosus 6300.0 1500.0 9 PMID:16380267;PMID:17521919;PMID:20387014 -3.1.1.3 * streptomyces rimosus 203.0 186.5 2 * -3.1.1.3 * struthio camelus 6000.0 6000.0 1 * -3.1.1.3 * sus scrofa 5120.0 70.0 5 PMID:23977086;PMID:7278671;PMID:9799112 -3.1.1.3 * thermomyces dupontii 24110.0 8454.0 8 PMID:22766036;PMID:29859246 -3.1.1.3 * thermosyntropha lipolytica 14.0 13.7 2 PMID:17933930 -3.1.1.3 * thermus thermophilus 0.076 0.076 1 PMID:15862353 -3.1.1.3 * triticum aestivum 0.6225 0.6212500000000001 2 PMID:34266327 -3.1.1.3 * uncultured bacterium 2022.0 1027.5 2 PMID:21678056 -3.1.1.3 * yarrowia lipolytica 22900.0 12260.0 9 PMID:16624574;PMID:16931141;PMID:17321147 -3.1.1.31 * bos taurus 55.2 55.2 1 PMID:6852020 -3.1.1.31 * enterococcus faecalis 520.0 520.0 1 PMID:25385794 -3.1.1.31 * homo sapiens 3330.0 1065.0 3 PMID:11277923;PMID:11457850;PMID:21443518 -3.1.1.31 * mus musculus 1.18 1.18 1 PMID:12831846 -3.1.1.31 * plasmodium berghei 1.0 1.0 1 PMID:11277923 -3.1.1.31 * plasmodium falciparum 60.0 60.0 3 PMID:11457850;PMID:21443518 -3.1.1.31 * trypanosoma brucei 6753.0 3466.5 2 PMID:10867008;PMID:11457850 -3.1.1.32 * bos taurus 2.95 2.375 2 PMID:8034719;PMID:8631903 -3.1.1.32 * escherichia coli 84.0 84.0 1 PMID:11997123 -3.1.1.32 * katsuwonus pelamis 0.22 0.22 1 PMID:10666567 -3.1.1.32 * manduca sexta 8.72 8.72 1 PMID:6833259 -3.1.1.32 * mesocricetus auratus 1.155 1.155 1 PMID:3119595 -3.1.1.32 * polybia paulista 2898.0 2898.0 1 PMID:17761205 -3.1.1.32 * rattus norvegicus 155.0 13.4915 6 PMID:15589222;PMID:2051928;PMID:7142153;PMID:7278676 -3.1.1.32 * serratia sp. xjf1 202.3 202.3 1 PMID:22578870 -3.1.1.32 * streptomyces albidoflavus 588.0 588.0 1 PMID:23772365 -3.1.1.32 * sus scrofa 1192.0 596.21 2 PMID:12573445;PMID:24368210 -3.1.1.32 * thermomyces lanuginosus 4403.0 2277.5 4 PMID:27821336 -3.1.1.32 * trichoderma atroviride 1220.0 1220.0 1 * -3.1.1.32 * trypanosoma brucei 3.0 3.0 1 PMID:17402937 -3.1.1.32 * trypanosoma cruzi 0.35 0.35 1 PMID:11311140 -3.1.1.34 * cavia porcellus 580.0 580.0 1 PMID:6802184 -3.1.1.34 * homo sapiens 431.6 47.75 5 PMID:11483618;PMID:3782053;PMID:641046;PMID:7236660 -3.1.1.34 * oncorhynchus mykiss 0.024 0.024 1 PMID:7115310 -3.1.1.34 * rattus norvegicus 10.77 6.4005 2 PMID:510696;PMID:863923 -3.1.1.34 * rhizopus japonicus 2.14 2.14 1 * -3.1.1.34 * sus scrofa 56.95 56.95 1 PMID:4362067 -3.1.1.35 * acinetobacter calcoaceticus 1500.0 157.5 4 PMID:10601844;PMID:12542698 -3.1.1.35 * arthrobacter sp. 99.5 99.5 1 PMID:9055403 -3.1.1.35 * geobacillus sp. 15.8 15.8 1 * -3.1.1.35 * melilotus albus 1636.0 1636.0 1 PMID:14458747 -3.1.1.36 * citrus nobilis x citrus deliciosa 566.0 566.0 1 * -3.1.1.36 * citrus sinensis 2.6 2.6 1 PMID:15186095 -3.1.1.4 * aeropyrum pernix 249.0 249.0 1 PMID:15135393 -3.1.1.4 * arabidopsis thaliana 35.5 17.8 15 PMID:17692835 -3.1.1.4 * bos taurus 2910.0 0.064 9 PMID:11909855;PMID:6860643;PMID:8505299;PMID:9787801 -3.1.1.4 * bothrocophias hyoprora 408.3 204.3 2 PMID:21496495 -3.1.1.4 * bothrops jararacussu 290.0 274.5 4 PMID:14644553 -3.1.1.4 * bothrops leucurus 159.9 114.6 2 PMID:21699995 -3.1.1.4 * bothrops spp. 37.08 37.08 1 PMID:11018293 -3.1.1.4 * bungarus multicinctus 1450.0 727.95 2 PMID:32180;PMID:7217035 -3.1.1.4 * caenorhabditis elegans 0.847 0.847 2 PMID:23007400 -3.1.1.4 * camelus dromedarius 600.0 357.5 2 PMID:16733083;PMID:35684381 -3.1.1.4 * cavia porcellus 1030.0 8.4 7 PMID:8344288 -3.1.1.4 * craspedocephalus borneensis 11.7 8.100000000000001 4 PMID:15955061 -3.1.1.4 * craspedocephalus puniceus 74.3 6.2 8 PMID:15955061 -3.1.1.4 * crotalus adamanteus 3250.0 3150.0 3 PMID:32180 -3.1.1.4 * crotalus lutosus 0.01587 0.01587 1 PMID:26996495 -3.1.1.4 * daboia russelii russelii 0.347 0.23399999999999999 2 PMID:16997639 -3.1.1.4 * daboia siamensis 1620.0 1620.0 1 PMID:34437392 -3.1.1.4 * dasyatis pastinaca 750.0 520.0 2 PMID:21329523;PMID:23898481 -3.1.1.4 * echis carinatus 2312.0 1034.0 3 PMID:20723574;PMID:7846689 -3.1.1.4 * equus caballus 6671.0 0.019049999999999997 4 PMID:10946009;PMID:6860643 -3.1.1.4 * gallus gallus 400.0 200.1 2 PMID:19645724 -3.1.1.4 * gloydius halys 62000.0 1500.0 7 PMID:10209288;PMID:23143242 -3.1.1.4 * hexaplex trunculus 180.0 90.36 2 PMID:19932080 -3.1.1.4 * homo sapiens 9300.0 0.133 58 PMID:1599975;PMID:16691004;PMID:16962371;PMID:1730245;PMID:1903717;PMID:19376232;PMID:20705608;PMID:6860643;PMID:8328965;PMID:8399335;PMID:8940072;PMID:9214693;PMID:922032;PMID:9767110 -3.1.1.4 * hydrophis hardwickii 29.0 23.0 2 PMID:12727275 -3.1.1.4 * macrovipera lebetina transmediterranea 63.51 63.51 1 PMID:19351557 -3.1.1.4 * meleagris gallopavo 167.0 167.0 1 PMID:14586101 -3.1.1.4 * mesocricetus auratus 0.5 0.2596 2 PMID:3119595;PMID:8940072;PMID:9767110 -3.1.1.4 * micropechis ikaheca 0.837 0.353 3 PMID:11342029 -3.1.1.4 * mus musculus 0.381 0.2125 8 PMID:20705608 -3.1.1.4 * naja kaouthia 243.1 117.1 16 PMID:15081888 -3.1.1.4 * naja melanoleuca 11400.0 1220.0 9 PMID:1730245 -3.1.1.4 * naja naja 2100.0 1114.5 8 PMID:15134835;PMID:16494989;PMID:6838196;PMID:7278679 -3.1.1.4 * oryctolagus cuniculus 290.0 164.0 2 PMID:10833266;PMID:2223865 -3.1.1.4 * ovis aries 4.725 4.725 1 PMID:7278677 -3.1.1.4 * pagrus major 1294.0 1293.0 3 PMID:11201998 -3.1.1.4 * patiria pectinifera 119000.0 59500.0435 2 * -3.1.1.4 * pectobacterium carotovorum 0.0379 0.0379 1 * -3.1.1.4 * photobacterium damselae 2.08 2.08 1 PMID:24601085 -3.1.1.4 * protobothrops flavoviridis 6410.0 3855.0 2 PMID:12144;PMID:7419504 -3.1.1.4 * protobothrops jerdonii 39.4 39.4 1 PMID:12220717 -3.1.1.4 * rattus norvegicus 5000.0 2.5 10 PMID:10461922;PMID:4202714;PMID:7998924;PMID:8148815 -3.1.1.4 * solanum tuberosum 127.0 109.0 3 PMID:11589694 -3.1.1.4 * streptomyces cinnamoneus 1.05 1.05 1 * -3.1.1.4 * struthio camelus 840.0 840.0 1 PMID:17656163 -3.1.1.4 * sus scrofa 16000.0 615.0 41 PMID:1091;PMID:1730245;PMID:3295782;PMID:4475346;PMID:4772678;PMID:4819758;PMID:6838196;PMID:6860643 -3.1.1.4 * trimorphodon lambda 27.7 27.7 1 PMID:15225559 -3.1.1.4 * vibrio mimicus 21.8 21.8 1 PMID:12387827 -3.1.1.4 * vicia faba 0.0069 0.0069 1 PMID:10889255 -3.1.1.40 * lasallia pustulata 1300.0 1300.0 1 PMID:5116606 -3.1.1.41 * amycolatopsis lactamdurans 205.0 205.0 1 PMID:11030579 -3.1.1.41 * bacillus subtilis 2949.0 851.5 8 PMID:16232499;PMID:23828600 -3.1.1.41 * halalkalibacterium halodurans 293.0 165.0 3 PMID:31986559 -3.1.1.41 * hapsidospora chrysogena 5.0 5.0 1 PMID:7998 -3.1.1.41 * limosilactobacillus antri 202.9 48.7 3 PMID:31986559 -3.1.1.41 * paenibacillus sp. r4 27.0 27.0 1 * -3.1.1.41 * rhodotorula glutinis 342.0 342.0 1 * -3.1.1.41 * thermotoga maritima 415.5 45.41 12 PMID:28097692 -3.1.1.42 * aspergillus japonicus 0.36 0.36 1 * -3.1.1.42 * aspergillus niger 6.2 6.2 1 PMID:15607224 -3.1.1.42 * aspergillus sojae 24.11 0.67 5 PMID:18773200 -3.1.1.42 * mycosarcoma maydis 6.38 6.38 1 PMID:27173527 -3.1.1.43 * acetobacter pasteurianus 667.0 380.25 2 PMID:11772629;PMID:4424889 -3.1.1.43 * bacillus mycoides 2160.0 2160.0 1 PMID:11432787 -3.1.1.43 * homo sapiens 5148.0 156.25 14 PMID:18256025 -3.1.1.43 * stenotrophomonas maltophilia 5.34 5.34 1 PMID:29556427 -3.1.1.43 * xanthomonas citri 2050.0 2050.0 1 * -3.1.1.45 * alcaligenes sp. 0.055 0.047 3 PMID:2394679 -3.1.1.45 * burkholderia cepacia 217.0 108.5325 2 PMID:2394679;PMID:7684040 -3.1.1.45 * cupriavidus necator 4.6 0.53 11 PMID:10742248;PMID:2394679 -3.1.1.45 * pseudomonas aeruginosa 0.02 0.02 1 PMID:18331335 -3.1.1.45 * pseudomonas knackmussii 205.5 61.9 4 PMID:3804973;PMID:7305906;PMID:9440530 -3.1.1.45 * pseudomonas reinekei 65.0 34.0 3 PMID:18789896 -3.1.1.45 * pseudomonas sp. 710.0 450.0 2 PMID:14617643 -3.1.1.45 * rhodococcus opacus 30.3 30.0 2 PMID:9495745 -3.1.1.45 * saccharolobus solfataricus 990.0 990.0 1 PMID:20655986 -3.1.1.47 * bos taurus 7.2 0.74725 4 PMID:17827718;PMID:7673213;PMID:8360169;PMID:9349753 -3.1.1.47 * cavia porcellus 20.3 20.3 1 PMID:7822257 -3.1.1.47 * homo sapiens 9.46 0.000221 13 PMID:11133692;PMID:11439095;PMID:16371369;PMID:18434304;PMID:18587071;PMID:3558407;PMID:8440681 -3.1.1.47 * mus musculus 0.038 0.026860000000000002 2 PMID:18434304;PMID:7921789 -3.1.1.47 * rattus norvegicus 27.1 0.1225 16 PMID:10867005;PMID:11105997;PMID:11420174;PMID:7451433 -3.1.1.47 * rhodnius prolixus 915.0 43.0 21 PMID:18835273 -3.1.1.47 * schizosaccharomyces pombe 1e-05 1e-05 1 PMID:18489912 -3.1.1.47 * sus scrofa 0.176 0.176 1 PMID:16272147 -3.1.1.48 * fusarium sambucinum 0.1 0.1 1 PMID:949472 -3.1.1.49 * brassica napus 8.3 8.3 1 PMID:18036206 -3.1.1.5 * candida albicans 459.0 218.95 4 PMID:2007179;PMID:7619859 -3.1.1.5 * cryptococcus neoformans 559.0 284.75 2 PMID:10749672 -3.1.1.5 * cyberlindnera jadinii 28.72 28.72 1 PMID:16495653 -3.1.1.5 * escherichia coli 23.5 13.075 2 PMID:238979;PMID:3908447 -3.1.1.5 * homo sapiens 27.3 2.448 3 PMID:19439193;PMID:6511790 -3.1.1.5 * hordeum vulgare 51.0 51.0 1 PMID:4083901 -3.1.1.5 * mus musculus 1.34 1.34 1 PMID:3384824 -3.1.1.5 * mycobacterium lepraemurium 0.61 0.61 1 PMID:8816850 -3.1.1.5 * oryctolagus cuniculus 7.58 7.58 1 PMID:1646935 -3.1.1.5 * penicillium chrysogenum 6730.0 6730.0 1 PMID:3365441 -3.1.1.5 * rattus norvegicus 12.24 1.7 5 PMID:15555596;PMID:7278668;PMID:8119970;PMID:8631810 -3.1.1.5 * saccharomyces cerevisiae 193.0 116.5 2 PMID:6368532 -3.1.1.5 * schizosaccharomyces pombe 2.71 2.71 1 PMID:8782402 -3.1.1.5 * sus scrofa 2.31 1.9849999999999999 2 PMID:7772041 -3.1.1.5 * vibrio cholerae serotype o1 0.404 0.404 1 PMID:24532770 -3.1.1.50 * oncorhynchus mykiss 0.000625 0.000305 3 * -3.1.1.50 * salmo salar 0.000665 0.000442 4 * -3.1.1.50 * sinapis alba 0.074 0.074 1 * -3.1.1.52 * bos taurus 0.742 0.742 1 PMID:7083039 -3.1.1.52 * mus musculus 1.45 0.405 7 PMID:19176526 -3.1.1.53 * [ruminococcus] torques 0.31 0.25 2 PMID:1398908 -3.1.1.53 * aspergillus niger 0.71 0.26 4 PMID:12008863 -3.1.1.53 * bacteroides sp. 0.465 0.465 1 PMID:1398908 -3.1.1.53 * bifidobacterium bifidum 0.16 0.16 1 PMID:1398908 -3.1.1.53 * bifidobacterium longum 0.18 0.18 1 PMID:1398908 -3.1.1.53 * bifidobacterium longum subsp. infantis 0.15 0.15 1 PMID:1398908;PMID:8358229 -3.1.1.53 * enterococcus faecalis 0.18 0.18 1 PMID:1398908 -3.1.1.53 * equus sp. 0.104 0.052059999999999995 2 PMID:18246423 -3.1.1.53 * escherichia coli 2.31 1.8 2 PMID:21557376 -3.1.1.53 * homo sapiens 0.15 0.15 1 PMID:1398908;PMID:8358229 -3.1.1.53 * mediterraneibacter gnavus 0.17 0.17 1 PMID:1398908 -3.1.1.53 * rattus norvegicus 12.8 6.22 4 PMID:12948030;PMID:2695768 -3.1.1.53 * streptococcus suis 1.8 1.8 1 PMID:21624352 -3.1.1.54 * tagetes patula 0.0156 0.0156 1 * -3.1.1.55 * camelus dromedarius 0.042 0.038 9 PMID:12948157;PMID:9231344;PMID:9876276 -3.1.1.55 * cavia porcellus 11.31 11.31 1 PMID:6704404 -3.1.1.55 * homo sapiens 0.039 0.039 1 PMID:10890581 -3.1.1.55 * mus musculus 0.08 0.057749999999999996 4 PMID:9231344 -3.1.1.55 * rattus norvegicus 2.55 0.0385 16 PMID:12948157;PMID:2383281;PMID:9231344;PMID:9876276 -3.1.1.56 * saccharomyces cerevisiae 11.0 11.0 1 PMID:10427036 -3.1.1.57 * phytopseudomonas straminea 495.0 247.0 3 PMID:15277747;PMID:6841353 -3.1.1.58 * aspergillus parasiticus 0.529 0.529 1 PMID:42541 -3.1.1.58 * caulobacter vibrioides 61.8 61.8 1 PMID:35932185 -3.1.1.58 * neurospora crassa 0.0046 0.0046 1 PMID:6217857 -3.1.1.59 * leptinotarsa decemlineata 1.841 0.0135 3 PMID:9177132 -3.1.1.59 * manduca sexta 1050000.0 500000.0 3 PMID:20307057;PMID:4062303 -3.1.1.59 * spodoptera frugiperda 0.0025 0.0025 1 * -3.1.1.59 * spodoptera littoralis 0.0007 0.0007 1 * -3.1.1.59 * tenebrio molitor 350.0 5.3 5 PMID:12706627 -3.1.1.59 * trichoplusia ni 0.179 0.179 1 PMID:3651500 -3.1.1.6 * acetivibrio thermocellus 183.0 21.5 4 PMID:19968989 -3.1.1.6 * acinetobacter sp. 0.474 0.3245 6 * -3.1.1.6 * alicyclobacillus tolerans 221.3 124.45 2 PMID:31954783 -3.1.1.6 * aspergillus niger 16050.0 31.0 3 PMID:7445676 -3.1.1.6 * bacillus pumilus 118.8 118.8 1 PMID:10215579 -3.1.1.6 * bacillus subtilis 333.0 333.0 1 PMID:18203225 -3.1.1.6 * bos taurus 376.0 376.0 1 PMID:3689793 -3.1.1.6 * candida bororiensis 0.021 0.021 1 PMID:1245482 -3.1.1.6 * cellvibrio japonicus 395.0 5.0 9 PMID:19968989 -3.1.1.6 * drosophila mojavensis 0.8 0.8 1 * -3.1.1.6 * eleusine coracana 5.39 1.831 6 PMID:17263491 -3.1.1.6 * escherichia coli 250.0 250.0 1 PMID:17305603 -3.1.1.6 * exiguobacterium antarcticum 3.79 3.79 1 PMID:31229546 -3.1.1.6 * fibrobacter succinogenes 2933.0 2933.0 1 PMID:2082827 -3.1.1.6 * kluyveromyces marxianus 324.0 324.0 1 PMID:18029043 -3.1.1.6 * lactiplantibacillus plantarum 7.87 7.87 1 * -3.1.1.6 * lichtheimia corymbifera 221.9 111.21000000000001 2 * -3.1.1.6 * meyerozyma guilliermondii 71.4 71.4 1 PMID:10736022 -3.1.1.6 * nocardia sp. 1104.0 1104.0 1 PMID:4436255 -3.1.1.6 * pantoea dispersa 530.0 492.5 2 PMID:31127451 -3.1.1.6 * podospora anserina 104.85 7.970000000000001 6 PMID:26329850 -3.1.1.6 * streptomyces lividans 715.0 715.0 1 PMID:8920994 -3.1.1.6 * streptomyces olivochromogenes 110.9 110.9 1 * -3.1.1.6 * streptomyces sp. 1027.0 71.0 3 * -3.1.1.6 * talaromyces purpureogenus 139.8 128.95 2 PMID:8756392 -3.1.1.6 * trichoderma reesei 20.5 0.53 8 PMID:18978092 -3.1.1.6 * wickerhamomyces anomalus 0.000347 0.00034449999999999997 2 PMID:17976172 -3.1.1.60 * achromobacter denitrificans 89.5 89.5 1 * -3.1.1.60 * triticum aestivum 0.00077 0.00077 1 PMID:6468391 -3.1.1.65 * pullularia pullulans 0.17 0.00335 4 * -3.1.1.65 * scheffersomyces stipitis 0.5 0.5 1 * -3.1.1.65 * schwanniomyces polymorphus 0.51 0.47 2 * -3.1.1.67 * homo sapiens 0.04433 0.025 5 PMID:11441128;PMID:2354155;PMID:2599089;PMID:8555260 -3.1.1.67 * oryctolagus cuniculus 0.0112 0.00575 2 PMID:6487591;PMID:6487592 -3.1.1.67 * rattus norvegicus 0.035 0.0133 7 PMID:11424227;PMID:1429692;PMID:9049433 -3.1.1.7 * alca torda 0.645 0.5745 2 PMID:17113132 -3.1.1.7 * bactrocera dorsalis 690.0 2.082 7 PMID:15315367;PMID:23007913 -3.1.1.7 * bos taurus 372.0 187.7 5 PMID:16989325;PMID:17208293;PMID:7765265 -3.1.1.7 * bungarus multicinctus 4290.0 4290.0 1 PMID:155947 -3.1.1.7 * carassius auratus auratus 224.1 224.1 1 PMID:15177947 -3.1.1.7 * cavia porcellus 9.13 9.13 1 PMID:4699242 -3.1.1.7 * cyprinus carpio 4970.0 2573.0 2 PMID:19121395 -3.1.1.7 * danio rerio 0.379 0.2515 2 PMID:30981910 -3.1.1.7 * dendrobaena veneta 39.5 34.1 3 PMID:8681969 -3.1.1.7 * diopatra neapolitana 107.7 107.7 1 PMID:27777085 -3.1.1.7 * drosophila melanogaster 36370.0 31305.0 2 PMID:18570631 -3.1.1.7 * eisenia andrei 0.0498 0.0425 3 * -3.1.1.7 * electrophorus electricus 349.0 176.25 2 PMID:16989325;PMID:19007306 -3.1.1.7 * eledone moschata 700.0 700.0 1 PMID:9761457 -3.1.1.7 * fratercula arctica 0.474 0.46499999999999997 2 PMID:17113132 -3.1.1.7 * gallus gallus 14.58 8.395 4 PMID:8168228 -3.1.1.7 * gambusia yucatana 0.12024 0.12024 1 PMID:27730276 -3.1.1.7 * gammarus pulex 0.0478 0.024 3 PMID:17532548 -3.1.1.7 * haemonchus contortus 2293.0 2293.0 1 * -3.1.1.7 * heterorhabditis bacteriophora 1560.0 65.8 12 PMID:17531543;PMID:26545490;PMID:28043327 -3.1.1.7 * homo sapiens 4572.0 26.0 12 PMID:16269140;PMID:16397771;PMID:23494216;PMID:4847222;PMID:5073758;PMID:7794533 -3.1.1.7 * liposcelis entomophila 2.295 0.5916399999999999 6 PMID:20824823 -3.1.1.7 * locusta migratoria manilensis 0.0038 0.00107 8 * -3.1.1.7 * macroptilium atropurpureum 0.957 0.957 1 PMID:18046576 -3.1.1.7 * mus musculus 7700.0 7700.0 1 PMID:12672481 -3.1.1.7 * musca domestica 752.0 671.0 2 PMID:836849;PMID:953031 -3.1.1.7 * mytilus galloprovincialis 13.2 13.2 1 PMID:11311211 -3.1.1.7 * nephotettix cincticeps uhler 123.0 28.75 6 * -3.1.1.7 * oncorhynchus mykiss 187.0 187.0 1 PMID:15177947 -3.1.1.7 * ovis aries 21.0 21.0 1 PMID:21499785 -3.1.1.7 * pardosa pseudoannulata 0.315 0.12 5 PMID:28036068 -3.1.1.7 * plutella xylostella 448.3 448.3 1 * -3.1.1.7 * pseudorasbora parva 236.2 236.2 1 PMID:15177947 -3.1.1.7 * rhopalosiphum padi 0.0704 0.044050000000000006 2 PMID:23879406 -3.1.1.7 * rhynchophorus ferrugineus 3504.0 3241.5 2 PMID:31751747 -3.1.1.7 * rhyzopertha dominica 4.7 4.7 1 PMID:9669090 -3.1.1.7 * sitobion avenae 0.0986 0.059449999999999996 2 PMID:23879406 -3.1.1.7 * uria aalge 0.389 0.357 2 PMID:17113132 -3.1.1.7 * walterinnesia aegyptia 357.0 357.0 1 PMID:8725010 -3.1.1.7 * zea mays 82.5 82.5 1 PMID:15980188 -3.1.1.72 * acidothermus cellulolyticus 17250.0 17250.0 1 PMID:29170828 -3.1.1.72 * arion ater 99.73 78.12 3 PMID:35566348 -3.1.1.72 * aspergillus awamori 19.7 6.6 3 PMID:15848131 -3.1.1.72 * aspergillus luchuensis 21.9 15.6 2 PMID:28802264 -3.1.1.72 * aspergillus niger 31.0 31.0 1 * -3.1.1.72 * aspergillus oryzae 0.35 0.35 1 PMID:34376338 -3.1.1.72 * bacillus pumilus 186.5 152.65 2 PMID:10215579;PMID:15769599 -3.1.1.72 * bacillus subtilis 2949.0 1024.0 6 PMID:23828600 -3.1.1.72 * caldanaerobacter subterraneus 104.0 104.0 1 PMID:24317066 -3.1.1.72 * caldanaerobacter subterraneus subsp. tengcongensis 2.8 0.265 8 PMID:36054591 -3.1.1.72 * chlamydomonas reinhardtii 800.0 639.0 2 PMID:30873405 -3.1.1.72 * clostridium cellulovorans 121.5 121.5 1 PMID:12450866 -3.1.1.72 * fibrobacter succinogenes 2933.0 113.0 3 PMID:16333341;PMID:2082827 -3.1.1.72 * halalkalibacterium halodurans 501.0 229.0 4 PMID:31986559 -3.1.1.72 * irpex lacteus 16.8 16.8 1 PMID:34429691 -3.1.1.72 * limosilactobacillus antri 499.5 125.80000000000001 4 PMID:31986559 -3.1.1.72 * neocallimastix frontalis 100.1 100.1 1 * -3.1.1.72 * neocallimastix patriciarum 2614.0 726.7 6 PMID:19690850 -3.1.1.72 * ochrovirga pacifica 40.08 40.08 1 PMID:31286972 -3.1.1.72 * orpinomyces sp. 0.49 0.255 4 PMID:10473406 -3.1.1.72 * paenibacillus sp. r4 27.0 27.0 1 * -3.1.1.72 * penicillium chrysogenum 4.8 4.8 1 PMID:28950907 -3.1.1.72 * phanerodontia chrysosporium 39.86 39.86 2 PMID:23287498;PMID:23474097 -3.1.1.72 * rasamsonia emersonii 28.0 14.7 2 PMID:22407679 -3.1.1.72 * schizophyllum commune 227.0 3.23 8 PMID:14572903;PMID:21029756;PMID:8980647 -3.1.1.72 * streptomyces lividans 55.3 0.1 13 PMID:12880945;PMID:21029756 -3.1.1.72 * talaromyces purpureogenus 139.8 3.23 8 PMID:21029756;PMID:8756392 -3.1.1.72 * termitomyces clypeatus 80.0 80.0 1 PMID:12790630 -3.1.1.72 * thermobifida fusca 109100.0 25.6 3 PMID:16348531;PMID:20816933;PMID:22578869 -3.1.1.72 * thermothelomyces thermophilus 8.3 4.150650000000001 2 PMID:25037346 -3.1.1.72 * trichoderma reesei 31.6 0.4 6 PMID:21029756 -3.1.1.73 * acetivibrio thermocellus 26.6 26.6 1 PMID:10671457 -3.1.1.73 * actinomyces sp. oral taxon 448 477.6 326.0 2 PMID:26497017 -3.1.1.73 * alternaria alternata 18.39 18.39 1 * -3.1.1.73 * alternaria tenuissima 11.2 11.2 1 * -3.1.1.73 * anaeromyces mucronatus 10.6 7.0 3 PMID:27026329 -3.1.1.73 * aspergillus awamori 65.1 2.4299999999999997 46 PMID:18830967;PMID:20138908;PMID:9836439 -3.1.1.73 * aspergillus nidulans 21.7 20.3 3 PMID:17043824;PMID:22770893 -3.1.1.73 * aspergillus niger 156.0 0.9490000000000001 30 PMID:16714088;PMID:20801026;PMID:29349547;PMID:8679110 -3.1.1.73 * aspergillus ochraceus 57.9 57.9 1 * -3.1.1.73 * aspergillus sp. 26.0 13.615 2 PMID:10231593 -3.1.1.73 * aspergillus terreus 720.0 296.6 4 PMID:23606660;PMID:29697197 -3.1.1.73 * aureobasidium pullulans 74.6 35.3 11 PMID:12957952 -3.1.1.73 * bacillus pumilus 1009.54 377.9 5 PMID:32531366;PMID:34071417 -3.1.1.73 * bacteroides intestinalis 1.29 0.022 7 PMID:35316064 -3.1.1.73 * burkholderia pyrrocinia 41.78 36.935 4 PMID:35036272 -3.1.1.73 * butyrivibrio proteoclasticus 199.0 6.9 9 PMID:20058325 -3.1.1.73 * caldanaerobacter subterraneus subsp. tengcongensis 36.0 0.462 11 PMID:20127235 -3.1.1.73 * cellvibrio japonicus 50.0 12.4 5 PMID:20821249 -3.1.1.73 * dickeya dadantii 0.033 0.0175 4 PMID:21169494 -3.1.1.73 * eleusine coracana 26.8 26.8 1 PMID:17944530 -3.1.1.73 * equus quagga 10.4 10.4 1 PMID:22441123 -3.1.1.73 * fusarium oxysporum 6.94 6.94 1 * -3.1.1.73 * fusarium proliferatum 13.1 6.699999999999999 4 * -3.1.1.73 * lactarius hatsudake 13.14 9.66 3 PMID:27519296 -3.1.1.73 * lactobacillus crispatus 13.55 13.55 1 PMID:31129518 -3.1.1.73 * lentilactobacillus buchneri 0.053 0.0205 4 PMID:36569051 -3.1.1.73 * mycothermus thermophilus 5.5626 2.4761 6 * -3.1.1.73 * neocallimastix sp. 11.2 7.55 2 PMID:1482195 -3.1.1.73 * neurospora crassa 0.57 0.43000000000000005 4 PMID:14595525 -3.1.1.73 * parageobacillus thermoglucosidasius 161.7 83.76 4 PMID:31201678 -3.1.1.73 * penicillium expansum 14.4 9.6 7 PMID:9449810 -3.1.1.73 * penicillium parvum 5.25 5.25 1 PMID:27171788 -3.1.1.73 * penicillium sumatraense 710.71 91.2 4 * -3.1.1.73 * pleurotus giganteus 170.0 170.0 1 PMID:25065258 -3.1.1.73 * pleurotus sapidus 1681.0 1354.0 2 PMID:26272349 -3.1.1.73 * rusa unicolor 16.6 16.6 1 PMID:22441123 -3.1.1.73 * streptomyces ambofaciens 800.0 200.0 12 PMID:19767844 -3.1.1.73 * streptomyces cinnamoneus 23.07 6.075 14 PMID:25093500 -3.1.1.73 * streptomyces olivochromogenes 1.51 0.85 2 PMID:1663152 -3.1.1.73 * talaromyces funiculosus 36.1 11.6 6 PMID:11082184 -3.1.1.73 * talaromyces piceae 22.0 22.0 1 * -3.1.1.73 * talaromyces pinophilus 33.7 28.5 4 PMID:1426561 -3.1.1.73 * thermobacillus xylanilyticus 29.2 29.2 1 PMID:36403470 -3.1.1.73 * thermoclostridium stercorarium 88.0 63.0 5 PMID:10747226 -3.1.1.73 * thermothelomyces heterothallicus 47.3 12.05 4 * -3.1.1.73 * thermothelomyces thermophilus 57.1 18.2 3 * -3.1.1.73 * thermothielavioides terrestris 6.06 6.06 1 PMID:31254227 -3.1.1.73 * uncultured bacterium 219.1 15.95 10 PMID:21266107;PMID:21757926;PMID:22750860 -3.1.1.73 * uncultured microorganism 57.05 48.525 2 PMID:29968147;PMID:31102076 -3.1.1.73 * xylanibacter ruminicola 49.1 49.1 1 PMID:31812598 -3.1.1.74 * acinetobacter baumannii 38030.0 38030.0 1 PMID:33108946 -3.1.1.74 * alternaria brassicicola 3302.0 137.0 20 PMID:20306187 -3.1.1.74 * arabidopsis thaliana 45.0 45.0 1 PMID:19996150 -3.1.1.74 * botrytis cinerea 0.00603 0.00603 1 * -3.1.1.74 * burkholderia cepacia 5359.0 5359.0 1 PMID:23863287 -3.1.1.74 * colletotrichum gloeosporioides 114.0 114.0 1 PMID:24910973 -3.1.1.74 * fusarium solani 3.65 3.65 1 PMID:36838293 -3.1.1.74 * fusarium vanettenii 228.0 199.0 2 PMID:30507170 -3.1.1.74 * malbranchea cinnamomea 1148.0 1148.0 1 PMID:28932264 -3.1.1.74 * pseudomonas putida 7030.0 7030.0 1 PMID:3130804 -3.1.1.74 * rhodococcus sp. rosl12 2190.0 2190.0 1 PMID:35314296 -3.1.1.74 * saccharomyces cerevisiae 350.0 200.0 3 PMID:18365751 -3.1.1.74 * thermobifida alba 14.5 9.19 2 PMID:25910960 -3.1.1.74 * thermobifida fusca 643.4 304.65 6 PMID:22239833;PMID:23604968 -3.1.1.74 * thermothielavioides terrestris 983.0 983.0 1 PMID:26041215 -3.1.1.74 * trichoderma harzianum 11.4 1.3 17 PMID:18987860 -3.1.1.75 * paecilomyces sp. ds1407 281.31 42.8 4 * -3.1.1.75 * penicillium expansum 1821.0 1821.0 1 PMID:28324398 -3.1.1.75 * pseudomonas sp. dsdy0501 2091.42 2091.42 1 PMID:31544013 -3.1.1.75 * rhodospirillum rubrum 74.0 74.0 1 PMID:15489436 -3.1.1.75 * shewanella sp. jkcm-aj-6,1a 58.35 36.845 2 * -3.1.1.75 * streptomyces sp. 12030.0 12030.0 1 * -3.1.1.75 * thermus thermophilus hb8 56.3 56.3 1 PMID:19214501 -3.1.1.76 * bdellovibrio bacteriovorus 55.0 55.0 1 PMID:22706067 -3.1.1.76 * caldimonas thermodepolymerans 25.0 25.0 1 PMID:15340783 -3.1.1.76 * pseudomonas fluorescens 76.0 47.7 2 PMID:20400568 -3.1.1.76 * pseudomonas indica 26.0 26.0 1 PMID:15340783 -3.1.1.76 * streptomyces exfoliatus 42.0 42.0 1 PMID:26156240 -3.1.1.76 * streptomyces sp. 17.7 17.7 1 PMID:12785312 -3.1.1.76 * streptomyces venezuelae 12.1 12.1 1 PMID:22695803 -3.1.1.77 * homo sapiens 1.555 0.7775025 2 PMID:1495428;PMID:2549069 -3.1.1.79 * bjerkandera adusta 31.58 1.78 3 PMID:28251842 -3.1.1.79 * bos taurus 30.0 2.6 11 PMID:2794798;PMID:2930517;PMID:3196730;PMID:3708011 -3.1.1.79 * homo sapiens 143.0 18.0 9 PMID:11277912;PMID:15260473;PMID:15716583;PMID:18492774;PMID:19018281 -3.1.1.79 * sus scrofa 21.0 21.0 1 PMID:2988858 -3.1.1.79 * uncultured bacterium 2065.0 2065.0 1 PMID:27328716 -3.1.1.79 * uncultured organism 5.76 5.76 1 PMID:28044227 -3.1.1.8 * alectoris rufa 61.35 61.35 1 PMID:8461052 -3.1.1.8 * aporrectodea caliginosa 0.092 0.092 1 * -3.1.1.8 * aporrectodea nocturna 0.096 0.096 1 * -3.1.1.8 * aporrectodea rosea 0.106 0.106 1 * -3.1.1.8 * columba livia 61.35 61.35 1 PMID:8461052 -3.1.1.8 * diopatra neapolitana 64.1 33.349999999999994 2 PMID:27777085 -3.1.1.8 * eisenia andrei 0.0498 0.0425 6 PMID:16753348 -3.1.1.8 * equus caballus 9.2 6.35 2 PMID:16989325 -3.1.1.8 * gambusia yucatana 0.00595 0.00595 1 PMID:27730276 -3.1.1.8 * homo sapiens 760.0 115.0 11 PMID:11368776;PMID:18208347;PMID:18602477;PMID:30384187;PMID:618874 -3.1.1.8 * lumbriculus variegatus 0.0987 0.04375 8 * -3.1.1.8 * lumbricus castaneus 0.26 0.26 1 * -3.1.1.8 * lumbricus terrestris 0.209 0.209 1 * -3.1.1.8 * rattus norvegicus 4612.0 4612.0 1 PMID:15106880 -3.1.1.8 * sus scrofa 360.0 360.0 1 PMID:29908755 -3.1.1.8 * vigna radiata var. radiata 0.096 0.096 1 PMID:16658363 -3.1.1.80 * rauvolfia serpentina 0.0364 0.0364 1 PMID:2955586 -3.1.1.80 * rauvolfia verticillata 2.484 2.484 1 PMID:16133216 -3.1.1.81 * bos taurus 0.013 0.013 1 PMID:15963993 -3.1.1.81 * capra hircus 0.013 0.013 1 PMID:15963993 -3.1.1.81 * equus caballus 0.014 0.014 1 PMID:15963993 -3.1.1.81 * homo sapiens 0.012 0.012 1 PMID:15963993 -3.1.1.81 * mus musculus 0.016 0.016 1 PMID:15963993 -3.1.1.81 * oryctolagus cuniculus 0.017 0.017 1 PMID:15963993 -3.1.1.81 * saccharococcus caldoxylosilyticus 256.0 256.0 1 PMID:21897031 -3.1.1.82 * chenopodium album 5.75 5.75 1 * -3.1.1.82 * raphanus sativus 0.021 0.01735 2 PMID:16384908 -3.1.1.83 * rhodococcus erythropolis 145.0 145.0 1 PMID:11157238 -3.1.1.84 * rhodococcus sp. (in: high g+c gram-positive bacteria) 43.92 43.92 1 PMID:10698749 -3.1.1.84 * stenotrophomonas maltophilia 3.5 3.5 1 PMID:1551831 -3.1.1.86 * aspergillus aculeatus 1.0 1.0 1 PMID:7592973 -3.1.1.86 * paenibacillus polymyxa 65.95 3.01 3 * -3.1.1.88 * escherichia coli 772.9 119.3 6 PMID:22409882 -3.1.1.88 * sphingobium faniae 5.32 3.035 2 PMID:32303545 -3.1.1.88 * sphingobium sp. 5.82 3.66 10 PMID:19581484 -3.1.1.92 * agrobacterium tumefaciens 12.6 12.6 1 PMID:17660282 -3.1.1.92 * hydrogenophaga intermedia 79.0 79.0 1 PMID:17660282 -3.1.1.93 * homo sapiens 7400.0 0.00954 3 PMID:22294686;PMID:25217485 -3.1.1.95 * streptomyces purpurascens 169.4 169.4 1 PMID:11004563 -3.1.11.1 * escherichia coli 0.018 0.018 1 PMID:6343375 -3.1.11.2 * escherichia coli 0.27 0.27 1 PMID:794874 -3.1.11.5 * escherichia coli 0.7 0.4 3 PMID:1096951;PMID:4916924 -3.1.11.6 * escherichia coli 267.0 267.0 1 PMID:18812402 -3.1.11.6 * thermotoga maritima 221.0 221.0 1 PMID:18812402 -3.1.13.1 * escherichia coli 68.3 34.17 2 PMID:336625;PMID:8557629 -3.1.13.1 * homo sapiens 0.004 0.004 1 PMID:922003 -3.1.13.1 * saccharomyces cerevisiae 970.0 970.0 1 PMID:11586897 -3.1.13.2 * avian myeloblastosis virus 0.1 0.1 1 PMID:4343966 -3.1.13.2 * rous-associated virus 0.1 0.1 1 PMID:4343966 -3.1.13.3 * escherichia coli 10.75 6.26 2 PMID:18023590;PMID:240824 -3.1.13.3 * flammulina velutipes 16.0 16.0 1 PMID:1369259 -3.1.13.3 * homo sapiens 7.1 7.1 1 PMID:18023590 -3.1.13.3 * mycolicibacterium smegmatis 14.9 14.9 1 PMID:18023590 -3.1.13.3 * rattus norvegicus 1.2 1.2 1 PMID:4294333 -3.1.13.4 * bos taurus 211000.0 105500.03125 2 PMID:10801819;PMID:6246077 -3.1.13.5 * escherichia coli 5.0 5.0 1 PMID:6263885 -3.1.14.1 * aspergillus flavipes 11.3 11.3 1 * -3.1.15.1 * agkistrodon bilineatus 0.02 0.02 1 PMID:15621516 -3.1.15.1 * agkistrodon piscivorus 0.013 0.013 1 PMID:15621516 -3.1.15.1 * bitis arietans 0.006 0.006 1 PMID:15621516 -3.1.15.1 * bitis gabonica 0.012 0.012 1 PMID:15621516 -3.1.15.1 * bitis nasicornis 0.019 0.019 1 PMID:15621516 -3.1.15.1 * bothriechis schlegelii 0.048 0.048 1 PMID:15621516 -3.1.15.1 * bothrops alternatus 0.013 0.013 1 PMID:15621516 -3.1.15.1 * bothrops asper 0.033 0.033 1 PMID:15621516 -3.1.15.1 * bothrops atrox 350.0 175.014 2 PMID:15621516;PMID:4348125 -3.1.15.1 * bothrops bilineatus 0.051 0.051 1 PMID:15621516 -3.1.15.1 * bothrops cotiara 0.01 0.01 1 PMID:15621516 -3.1.15.1 * bothrops jararaca 0.019 0.019 1 PMID:15621516 -3.1.15.1 * bothrops jararacussu 155.8 7.1 3 PMID:15621516;PMID:36828087 -3.1.15.1 * bothrops moojeni 0.033 0.033 1 PMID:15621516 -3.1.15.1 * bothrops neuwiedi 0.018 0.018 1 PMID:15621516 -3.1.15.1 * bothrops pradoi 0.043 0.043 1 PMID:15621516 -3.1.15.1 * bungarus fasciatus 0.006 0.006 1 PMID:15621516 -3.1.15.1 * calloselasma rhodostoma 0.018 0.018 1 PMID:15621516 -3.1.15.1 * causus rhombeatus 0.019 0.019 1 PMID:15621516 -3.1.15.1 * cerastes vipera 0.005 0.005 1 PMID:15621516 -3.1.15.1 * crotalus adamanteus 10.2 5.122 2 PMID:15621516;PMID:4374207 -3.1.15.1 * crotalus atrox 0.042 0.042 1 PMID:15621516 -3.1.15.1 * crotalus basiliscus 0.049 0.049 1 PMID:15621516 -3.1.15.1 * crotalus cerastes 0.015 0.01 2 PMID:15621516 -3.1.15.1 * crotalus cerberus 0.017 0.017 1 PMID:15621516 -3.1.15.1 * crotalus concolor 0.05 0.05 1 PMID:15621516 -3.1.15.1 * crotalus durissus 0.037 0.037 1 PMID:15621516 -3.1.15.1 * crotalus helleri 0.013 0.013 1 PMID:15621516 -3.1.15.1 * crotalus horridus 0.031 0.031 1 PMID:15621516 -3.1.15.1 * crotalus lutosus 0.05 0.05 1 PMID:15621516 -3.1.15.1 * crotalus molossus 0.026 0.026 1 PMID:15621516 -3.1.15.1 * crotalus oreganus oreganus 0.024 0.024 1 PMID:15621516 -3.1.15.1 * crotalus ruber 0.031 0.031 1 PMID:15621516 -3.1.15.1 * crotalus scutulatus 0.027 0.027 1 PMID:15621516 -3.1.15.1 * crotalus viridis viridis 0.052 0.052 1 PMID:15621516 -3.1.15.1 * daboia palaestinae 0.009 0.009 1 PMID:15621516 -3.1.15.1 * daboia russelii 0.045 0.045 1 PMID:15621516 -3.1.15.1 * deinagkistrodon acutus 0.016 0.016 1 PMID:15621516 -3.1.15.1 * echis carinatus 0.014 0.014 1 PMID:15621516 -3.1.15.1 * eristicophis macmahoni 0.009 0.009 1 PMID:15621516 -3.1.15.1 * gloydius blomhoffii 0.015 0.015 1 PMID:15621516 -3.1.15.1 * gloydius halys ussuriensis 0.016 0.016 1 PMID:15621516 -3.1.15.1 * hypnale hypnale 0.006 0.006 1 PMID:15621516 -3.1.15.1 * macrovipera lebetinus 0.012 0.012 1 PMID:15621516 -3.1.15.1 * metlapilcoatlus nummifer 0.004 0.004 1 PMID:15621516 -3.1.15.1 * montivipera xanthina 0.009 0.009 1 PMID:15621516 -3.1.15.1 * naja atra 0.071 0.071 1 PMID:15621516 -3.1.15.1 * naja haje 0.11 0.11 1 PMID:15621516 -3.1.15.1 * naja kaouthia 0.075 0.075 1 PMID:15621516 -3.1.15.1 * naja melanoleuca 0.079 0.079 1 PMID:15621516 -3.1.15.1 * naja mossambica 0.05 0.05 1 PMID:15621516 -3.1.15.1 * naja naja 0.078 0.078 1 PMID:15621516 -3.1.15.1 * naja nigricollis 0.052 0.052 1 PMID:15621516 -3.1.15.1 * naja nivea 0.093 0.093 1 PMID:15621516 -3.1.15.1 * naja oxiana 0.087 0.087 1 PMID:15621516 -3.1.15.1 * naja pallida 0.039 0.039 1 PMID:15621516 -3.1.15.1 * naja sputatrix 0.062 0.062 1 PMID:15621516 -3.1.15.1 * ophiophagus hannah 0.014 0.014 1 PMID:15621516 -3.1.15.1 * porthidium lansbergii 0.008 0.008 1 PMID:15621516 -3.1.15.1 * porthidium nasutum 0.014 0.014 1 PMID:15621516 -3.1.15.1 * pseudocerastes persicus 0.01 0.01 1 PMID:15621516 -3.1.15.1 * sistrurus miliarius barbouri 0.007 0.007 1 PMID:15621516 -3.1.15.1 * sistrurus tergeminus 0.067 0.067 1 PMID:15621516 -3.1.15.1 * trimeresurus stejnegeri 1.3 1.3 1 PMID:20331418 -3.1.15.1 * vipera ammodytes 0.008 0.008 1 PMID:15621516 -3.1.15.1 * vipera aspis 11.2 5.6025 2 PMID:15621516;PMID:196525 -3.1.15.1 * vipera berus 0.006 0.006 1 PMID:15621516 -3.1.15.1 * vipera latastei 0.007 0.007 1 PMID:15621516 -3.1.15.1 * walterinnesia aegyptia 3.4 3.4 1 PMID:21660866 -3.1.16.1 * bos taurus 855.0 44.15 10 PMID:13740043;PMID:6272231 -3.1.16.1 * cavia porcellus 0.123 0.123 1 PMID:182133 -3.1.16.1 * rattus norvegicus 3.45 3.45 1 PMID:182133 -3.1.2.1 * mus musculus 74.4 74.4 1 PMID:23709691 -3.1.2.1 * rattus norvegicus 329.0 329.0 1 PMID:11322891 -3.1.2.10 * clostridium kluyveri 90.0 90.0 1 PMID:14063284 -3.1.2.11 * rattus norvegicus 0.039 0.039 1 PMID:640138 -3.1.2.12 * [candida] boidinii 1350.0 1350.0 1 PMID:7397203 -3.1.2.12 * arabidopsis thaliana 36.3 8.05 8 PMID:11888210 -3.1.2.12 * homo sapiens 5800.0 3390.0 5 PMID:4200890;PMID:4436331;PMID:6276656;PMID:7484406;PMID:93000 -3.1.2.12 * lota maculosa 26.9 26.9 1 PMID:7484406 -3.1.2.12 * rattus norvegicus 208.0 0.965 16 PMID:7484406;PMID:9059641 -3.1.2.12 * saccharomyces cerevisiae 11.0 11.0 1 PMID:10427036 -3.1.2.13 * homo sapiens 3150.0 3150.0 1 PMID:457667 -3.1.2.14 * allium ampeloprasum 0.144 0.144 1 PMID:7622515 -3.1.2.14 * cucurbita moschata 11.0 11.0 1 PMID:1391766 -3.1.2.14 * cuphea lanceolata 0.0018 0.0018 1 PMID:24178501 -3.1.2.14 * diploknema butyracea 192.0 96.345 2 * -3.1.2.14 * macadamia tetraphylla 1.61 0.5905 8 PMID:21071236 -3.1.2.14 * mangifera indica 0.18 0.18 1 PMID:21130480 -3.1.2.14 * persea americana 150.0 150.0 1 PMID:30409 -3.1.2.14 * umbellularia californica 1500.0 757.5 2 PMID:11330715 -3.1.2.17 * rattus norvegicus 1.41 1.41 1 PMID:3071714;PMID:6885824 -3.1.2.19 * mesocricetus auratus 0.11 0.11 1 PMID:2901416 -3.1.2.2 * anas platyrhynchos 45.4 45.4 1 PMID:3882056 -3.1.2.2 * arabidopsis thaliana 21.0 21.0 2 PMID:14660652 -3.1.2.2 * bos taurus 6.0 6.0 1 PMID:3674876 -3.1.2.2 * buckleyzyma aurantiaca 108.0 108.0 2 PMID:11279019 -3.1.2.2 * cavia porcellus 0.021 0.021 1 PMID:41517 -3.1.2.2 * cereibacter sphaeroides 67.5 54.55 2 PMID:2872920 -3.1.2.2 * cricetulus griseus 0.086 0.086 1 PMID:9163348 -3.1.2.2 * diutina rugosa 90.0 90.0 1 PMID:8837745 -3.1.2.2 * escherichia coli 320.0 93.8 3 PMID:1645722;PMID:235694;PMID:4554913;PMID:4871199 -3.1.2.2 * euglena gracilis 9.5 9.5 1 PMID:2857556 -3.1.2.2 * homo sapiens 198.0 198.0 1 PMID:10578051 -3.1.2.2 * mougeotia scalaris 0.2 0.2 1 PMID:24221632 -3.1.2.2 * mycolicibacterium smegmatis 230.0 224.5 2 PMID:7334001 -3.1.2.2 * oryctolagus cuniculus 1.8 0.315 10 PMID:10410378;PMID:10637771;PMID:6498215 -3.1.2.2 * pseudomonas aeruginosa 280.0 280.0 1 PMID:41836 -3.1.2.2 * rattus norvegicus 1695.0 0.38 24 PMID:11223865;PMID:1347213;PMID:2570608;PMID:39553;PMID:39618;PMID:5042454;PMID:6102926;PMID:6105869;PMID:6108217;PMID:6115749;PMID:6116156;PMID:6117325;PMID:7722521;PMID:7909756;PMID:8100522;PMID:8105781;PMID:9163348;PMID:9293616 -3.1.2.2 * sus scrofa 2.7 2.7 1 PMID:35538 -3.1.2.20 * anas platyrhynchos 45.4 45.4 1 PMID:3882056 -3.1.2.20 * arabidopsis thaliana 21.0 21.0 1 PMID:14660652 -3.1.2.20 * bos taurus 6.0 6.0 1 PMID:3674876 -3.1.2.20 * buckleyzyma aurantiaca 108.0 108.0 1 PMID:11279019 -3.1.2.20 * cavia porcellus 0.021 0.021 1 PMID:41517 -3.1.2.20 * cereibacter sphaeroides 67.5 54.55 2 PMID:2872920 -3.1.2.20 * cricetulus griseus 0.086 0.086 1 PMID:9163348 -3.1.2.20 * diutina rugosa 90.0 90.0 1 PMID:8837745 -3.1.2.20 * escherichia coli 320.0 45.5 9 PMID:1645722;PMID:18576672;PMID:235694;PMID:4554913;PMID:4871199 -3.1.2.20 * euglena gracilis 9.5 9.5 1 PMID:2857556 -3.1.2.20 * homo sapiens 198.0 198.0 1 PMID:10578051 -3.1.2.20 * mougeotia scalaris 0.2 0.2 1 PMID:24221632 -3.1.2.20 * mus musculus 0.1198 0.0469 17 PMID:19405909 -3.1.2.20 * mycolicibacterium smegmatis 230.0 224.5 2 PMID:7334001 -3.1.2.20 * oryctolagus cuniculus 1.8 0.975 2 PMID:10637771;PMID:6498215 -3.1.2.20 * pseudomonas aeruginosa 280.0 280.0 1 PMID:41836 -3.1.2.20 * rattus norvegicus 1695.0 1.4224999999999999 20 PMID:1347213;PMID:2570608;PMID:39553;PMID:39618;PMID:5042454;PMID:6102926;PMID:6105869;PMID:6108217;PMID:6115749;PMID:6116156;PMID:6117325;PMID:7722521;PMID:7909756;PMID:8100522;PMID:8105781;PMID:9163348;PMID:9293616 -3.1.2.20 * sus scrofa 2.7 2.7 1 PMID:35538 -3.1.2.21 * umbellularia californica 5.17 5.17 1 PMID:1898097 -3.1.2.22 * bos taurus 0.067 0.067 1 PMID:7651163 -3.1.2.22 * canis lupus familiaris 0.0055 0.0055 1 PMID:20494602 -3.1.2.22 * homo sapiens 27.3 4.605 4 PMID:11440996;PMID:19439193 -3.1.2.23 * aromatoleum evansii 0.02 0.02 1 PMID:18542924 -3.1.2.27 * eubacterium sp. 61.0 61.0 1 PMID:9869646 -3.1.2.27 * homo sapiens 0.01602 0.00247 15 PMID:10817395;PMID:10884298 -3.1.2.28 * arabidopsis thaliana 1.97 1.6 2 PMID:22372525 -3.1.2.29 * dichapetalum cymosum 0.0295 0.0295 1 * -3.1.2.3 * mus musculus 3.98 2.56 2 PMID:16141203 -3.1.2.30 * cereibacter sphaeroides 200.0 200.0 1 PMID:20047909 -3.1.2.4 * bacillus cereus 0.073 0.073 1 PMID:18461320 -3.1.2.4 * homo sapiens 430.0 337.0 2 PMID:10989434 -3.1.2.4 * rattus norvegicus 427.0 427.0 1 PMID:10989434 -3.1.2.6 * aloe vera 536.4 536.4 1 PMID:2076100 -3.1.2.6 * bos taurus 134.6 134.6 1 PMID:2328024 -3.1.2.6 * cyberlindnera mrakii 31.9 31.9 1 * -3.1.2.6 * homo sapiens 2007.0 1414.5 2 PMID:4745654;PMID:8504817 -3.1.2.6 * mus musculus 920.0 767.35 2 PMID:7154968;PMID:7350914 -3.1.2.6 * rattus norvegicus 773.0 337.5 6 PMID:2804125;PMID:3382669;PMID:3814608;PMID:496013;PMID:9873823 -3.1.2.6 * saccharomyces cerevisiae 1.34 1.34 1 * -3.1.2.6 * spinacia oleracea 24.3 14.15 2 PMID:2090107 -3.1.2.6 * trypanosoma brucei 117.0 0.27 13 PMID:18848584 -3.1.2.6 * zea mays 65.0 65.0 1 PMID:2630289 -3.1.2.7 * homo sapiens 0.15 0.15 1 PMID:93000 -3.1.2.7 * mus musculus 0.369 0.369 1 PMID:13130552 -3.1.2.7 * spinacia oleracea 9.1 9.1 1 PMID:16658678 -3.1.21.1 * basidiobolus haptosporus 597200.0 305870.0 2 PMID:10931196 -3.1.21.1 * bos taurus 1009.0 992.0 2 PMID:15311926;PMID:17379186 -3.1.21.1 * cavia porcellus 0.05 0.05 1 PMID:6274408 -3.1.21.1 * equus caballus 3600.0 3600.0 1 * -3.1.21.1 * homo sapiens 0.096 0.033 3 PMID:10092662;PMID:413831 -3.1.21.1 * rattus sp. 14.2 14.2 1 PMID:7074091 -3.1.21.10 * saccharomyces cerevisiae 5.83e-06 5.83e-06 1 PMID:3903750 -3.1.21.4 * saccharolobus islandicus 4.1 4.1 1 PMID:16896525 -3.1.21.6 * mycolicibacterium smegmatis 9444.0 4731.0 2 PMID:16584627 -3.1.21.7 * bos taurus 0.52 0.52 1 PMID:833111 -3.1.21.7 * escherichia coli 10.0 8.835 2 PMID:16001;PMID:6246346 -3.1.21.9 * tequatrovirus t4 840000.0 840000.0 1 PMID:4550601 -3.1.22.1 * chlamys islandica 302000.0 302000.0 1 * -3.1.22.1 * homo sapiens 0.42 0.42 1 PMID:6248503 -3.1.22.1 * rattus sp. 0.002 0.002 1 PMID:6630162 -3.1.22.1 * sus scrofa 327.1 321.0 3 PMID:16734590;PMID:19292869 -3.1.25.1 * tequatrovirus t4 0.00167 0.00167 1 PMID:1271461 -3.1.26.11 * aspergillus nidulans 4.6 4.6 1 PMID:9144538 -3.1.26.13 * moloney murine leukemia virus 166.0 86.8 2 PMID:2410413 -3.1.26.3 * escherichia coli 5.4 3.06 2 PMID:374963;PMID:932008 -3.1.26.4 * bos taurus 50.83 50.83 1 PMID:4516197 -3.1.26.4 * caenorhabditis elegans 7.0 1.085 4 PMID:16403028 -3.1.26.4 * escherichia coli 15.2 1.1 7 PMID:10788800;PMID:12641469;PMID:16650002;PMID:2172991 -3.1.26.4 * geobacillus stearothermophilus 1.9 1.5 4 PMID:16343535;PMID:21664908 -3.1.26.4 * homo sapiens 22.0 22.0 1 PMID:1706718 -3.1.26.4 * saccharomyces cerevisiae 0.9244 0.9244 1 PMID:3049596 -3.1.26.4 * shewanella oneidensis mr-1 7.8 7.8 1 PMID:19120449 -3.1.26.4 * shewanella sp. 22.0 14.8 2 PMID:16650002 -3.1.26.4 * thermotoga maritima 3.6 3.6 1 PMID:20875084 -3.1.26.5 * rattus norvegicus 0.00703 0.00703 1 PMID:1605634 -3.1.27.8 * bos taurus 0.014 0.014 1 PMID:6246098 -3.1.3.1 * aeropyrum pernix 427.0 427.0 1 PMID:17256119 -3.1.3.1 * anabaena sp. 16.3 11.15 2 PMID:20632947 -3.1.3.1 * antarctic bacterium 1650.0 870.15 2 PMID:10672035;PMID:16593525 -3.1.3.1 * anticarsia gemmatalis 683.04 683.04 1 PMID:31257641 -3.1.3.1 * aspergillus caespitosus 50.4 50.4 1 PMID:17702460 -3.1.3.1 * bacillus licheniformis 295.89 295.89 1 * -3.1.3.1 * bacillus sp. (in: firmicutes) 200.0 200.0 1 * -3.1.3.1 * bacillus subtilis 515.0 515.0 1 PMID:23791800 -3.1.3.1 * burkholderia cenocepacia 14.72 2.5549999999999997 6 PMID:19376213 -3.1.3.1 * cobetia marina 3800.0 3800.0 1 PMID:25260971 -3.1.3.1 * dictyostelium sp. 0.7 0.49 4 PMID:12597899 -3.1.3.1 * echinococcus multilocularis 1.625 1.625 1 PMID:1799967 -3.1.3.1 * escherichia coli 48.33 48.33 1 * -3.1.3.1 * geobacillus stearothermophilus 4.43 4.43 1 PMID:10334954 -3.1.3.1 * helicoverpa armigera 33.0 33.0 1 PMID:16466860 -3.1.3.1 * homo sapiens 850.0 629.0 5 PMID:12109816;PMID:15177289;PMID:5666467 -3.1.3.1 * meriones unguiculatus 0.0556 0.0556 1 PMID:1799967 -3.1.3.1 * neurospora crassa 223.3 198.35000000000002 2 PMID:10920432;PMID:17176763 -3.1.3.1 * nilaparvata lugens 0.214 0.1535 2 * -3.1.3.1 * onchocerca ochengi 7.86 7.86 1 PMID:17850899 -3.1.3.1 * pasteurella multocida 7.78 7.78 1 PMID:17156125 -3.1.3.1 * pinctada fucata 20.0 20.0 1 * -3.1.3.1 * prevotella intermedia 356.3 356.3 1 PMID:9654126 -3.1.3.1 * pseudomonas aeruginosa 46.0 30.5 2 PMID:8454193 -3.1.3.1 * pseudomonas sp. 192.0 192.0 1 * -3.1.3.1 * rattus norvegicus 341.0 147.0 5 PMID:11381619;PMID:18719742;PMID:2065078;PMID:6787043 -3.1.3.1 * rhizopus microsporus var. microsporus 102.6 102.6 1 * -3.1.3.1 * saccharomyces cerevisiae 54.53 54.53 1 * -3.1.3.1 * serratia marcescens 106.0 30.8 5 PMID:10612744 -3.1.3.1 * shewanella sp. 950.0 950.0 1 PMID:15725663 -3.1.3.1 * sphingobium sp. tcm1 384.0 384.0 1 PMID:31832710 -3.1.3.1 * sphingomonas sp. bsar-1 1690.0 1690.0 1 PMID:31678193 -3.1.3.1 * terfezia claveryi 0.3 0.3 1 PMID:19689775 -3.1.3.1 * thermotoga neapolitana 1309.0 986.15 2 PMID:11265472;PMID:9322373 -3.1.3.1 * thermus sp. 30.8 30.8 1 * -3.1.3.1 * thermus yunnanensis 3200.0 3200.0 1 PMID:15955749 -3.1.3.1 * ulva pertusa 48.6 48.6 1 PMID:12784882 -3.1.3.1 * vibrio sp. 3707.0 3707.0 1 PMID:10862903 -3.1.3.1 * walterinnesia aegyptia 24.0 24.0 1 PMID:12503880 -3.1.3.10 * enterobacter cloacae 196.0 144.0 6 PMID:16193276 -3.1.3.10 * lathyrus oleraceus 637.0 368.5 4 PMID:13839934 -3.1.3.10 * pantoea sp. 3.5.1 5.92 5.92 1 PMID:26209662 -3.1.3.10 * pholiota microspora 2360.0 210.0 15 PMID:9972248 -3.1.3.102 * arabidopsis thaliana 1.1 1.1 1 PMID:22002057 -3.1.3.102 * capra hircus 22750.0 22750.0 1 * -3.1.3.102 * pisum sativum cv. bohatyr 0.00752 0.00752 1 PMID:22002057 -3.1.3.104 * bacillus subtilis 1.7 0.0063 5 PMID:26316208 -3.1.3.106 * arachis hypogaea 858.0 858.0 1 PMID:11891254 -3.1.3.106 * bos taurus 1.1 1.1 1 PMID:9820827 -3.1.3.11 * bacillus licheniformis 100.0 100.0 1 PMID:6296615 -3.1.3.11 * bos taurus 22.5 19.0 3 PMID:11126748;PMID:237195;PMID:239683;PMID:6296605 -3.1.3.11 * canis lupus familiaris 0.121 0.06709999999999999 2 PMID:31474665 -3.1.3.11 * cyberlindnera jadinii 73.0 73.0 1 PMID:237192 -3.1.3.11 * escherichia coli 24.2 24.2 1 PMID:11825604 -3.1.3.11 * euglena gracilis 30.4 30.4 1 PMID:26214137 -3.1.3.11 * gallus gallus 57.0 20.725 4 PMID:20849;PMID:4029;PMID:6296607 -3.1.3.11 * heterostelium pallidum 5.5 5.5 1 PMID:237194 -3.1.3.11 * homo sapiens 12.9 12.9 1 PMID:6250626 -3.1.3.11 * kluyveromyces marxianus 36.0 36.0 1 PMID:6086609 -3.1.3.11 * lathyrus oleraceus 26.7 14.1 3 PMID:12651105 -3.1.3.11 * meleagris gallopavo 25.3 18.05 3 PMID:237473;PMID:6296606 -3.1.3.11 * methanococcus maripaludis 0.01 0.01 1 PMID:8288525 -3.1.3.11 * mus musculus 34.6 13.3 5 PMID:212415;PMID:40966;PMID:6296611 -3.1.3.11 * mycobacterium tuberculosis 1300.0 1300.0 1 PMID:21451980 -3.1.3.11 * mytilus galloprovincialis 4.899 4.899 1 * -3.1.3.11 * oryctolagus cuniculus 50.6 18.35 6 PMID:237193;PMID:4335956;PMID:6249201;PMID:6296607;PMID:6296611 -3.1.3.11 * oryza coarctata 3.67 2.44 2 PMID:11337074 -3.1.3.11 * ovis aries 0.1158 0.1158 1 * -3.1.3.11 * pelophylax lessonae 20.0 20.0 1 PMID:20656052 -3.1.3.11 * peltigera rufescens 1.91 1.91 1 PMID:16665052 -3.1.3.11 * ptyas dhumnades 48.0 48.0 1 PMID:6296609 -3.1.3.11 * pyrobaculum calidifontis 4.01 4.005 2 PMID:28299451 -3.1.3.11 * rattus norvegicus 34.0 29.0 5 PMID:2168409;PMID:2994743;PMID:4364115;PMID:6296610 -3.1.3.11 * rhodococcus opacus 20.45 7.605 4 * -3.1.3.11 * rhodopseudomonas palustris 8.81 8.81 1 PMID:4342108 -3.1.3.11 * ricinus communis 2.26 2.26 1 PMID:16663821 -3.1.3.11 * saccharomyces cerevisiae 110.0 46.1 3 PMID:232395;PMID:2834362;PMID:6327710 -3.1.3.11 * spinacia oleracea 119.0 85.5 6 PMID:2158892;PMID:6296613;PMID:9638644 -3.1.3.11 * sus scrofa 48.6 48.6 1 * -3.1.3.11 * sus scrofa domesticus 17.0 17.0 1 PMID:11126748 -3.1.3.11 * synechococcus sp. 15.0 13.35 2 PMID:8837735;PMID:9602137 -3.1.3.11 * thermotoga maritima 12.13 12.13 1 * -3.1.3.11 * trachemys scripta elegans 9.13 9.13 1 PMID:34680181 -3.1.3.11 * triticum aestivum 8.8 8.8 1 PMID:10910732 -3.1.3.11 * zea mays 62.5 62.5 1 PMID:6263905 -3.1.3.12 * cyberlindnera jadinii 0.4505 0.230415 2 PMID:24446217 -3.1.3.12 * phormia regina 2.61 1.6204999999999998 2 PMID:4326209 -3.1.3.12 * sulfolobus acidocaldarius 8.7 8.7 1 PMID:33008820 -3.1.3.12 * thermoproteus tenax 2.9 2.9 1 PMID:23626675 -3.1.3.15 * neurospora crassa 0.575 0.2615 8 PMID:4368540;PMID:4368541 -3.1.3.15 * saccharomyces cerevisiae 426.7 426.7 1 PMID:4351203 -3.1.3.15 * salmonella enterica subsp. enterica serovar typhimurium 677000.0 439500.0 2 PMID:6246956;PMID:83997 -3.1.3.15 * serratia marcescens 0.0503 0.0498 3 * -3.1.3.15 * streptomyces coelicolor 2.586 2.586 1 PMID:17851715 -3.1.3.16 * arabidopsis thaliana 8.95 8.95 1 PMID:11738087 -3.1.3.16 * bos taurus 0.003 0.003 1 PMID:9486768 -3.1.3.16 * candida albicans 1.2 0.6023 2 PMID:27578752 -3.1.3.16 * drosophila melanogaster 12.08 12.08 1 PMID:11747299 -3.1.3.16 * gallus gallus 2.5 2.5 1 PMID:2985450 -3.1.3.16 * homo sapiens 310.0 3.7 22 PMID:10931206;PMID:11495355;PMID:17081120;PMID:18200052;PMID:19420299;PMID:22639363;PMID:2831201 -3.1.3.16 * lambdavirus lambda 3870.0 3870.0 1 PMID:8394350 -3.1.3.16 * mus musculus 0.034 0.000292 3 PMID:17029793;PMID:18534252 -3.1.3.16 * neurospora crassa 1.2 1.2 1 PMID:8529028 -3.1.3.16 * oryctolagus cuniculus 0.9 0.9 1 PMID:2985385 -3.1.3.16 * plasmodium falciparum 220.0 0.13 3 PMID:10340482;PMID:11377737 -3.1.3.16 * pseudomonas aeruginosa 7.13 7.13 1 PMID:7499321 -3.1.3.16 * rattus norvegicus 0.081 0.07250000000000001 2 PMID:12972652 -3.1.3.16 * saccharomyces cerevisiae 1.8 1.55 2 PMID:12135475 -3.1.3.16 * solanum lycopersicum 0.245 0.034 3 PMID:12972652 -3.1.3.16 * synechocystis sp. 0.084 0.0044 13 PMID:16109928 -3.1.3.16 * trypanosoma brucei 19.5 19.5 1 PMID:11290414 -3.1.3.16 * tulipa gesneriana 380.0 190.305 2 PMID:17129401 -3.1.3.16 * zea mays 1.12 0.305 4 PMID:11004556 -3.1.3.17 * bos taurus 7.9 7.9 1 PMID:217307 -3.1.3.17 * oryctolagus cuniculus 2086.0 692.0 3 PMID:20939;PMID:240850 -3.1.3.17 * rattus norvegicus 0.00422 0.0021365 2 PMID:11716774 -3.1.3.17 * saccharomyces cerevisiae 407.0 407.0 1 PMID:6299361 -3.1.3.18 * chlamydomonas reinhardtii 86.5 86.5 1 PMID:11581250 -3.1.3.18 * homo sapiens 5.98 5.98 1 PMID:6258579 -3.1.3.18 * lathyrus oleraceus 12.9 12.9 1 * -3.1.3.18 * nicotiana tabacum 0.468 0.468 1 PMID:204630 -3.1.3.18 * saccharomyces cerevisiae 107.5 17.7 3 * -3.1.3.18 * spinacia oleracea 75.7 75.7 1 PMID:6322692 -3.1.3.18 * synechocystis sp. pcc 6803 5.4e-05 5.4e-05 1 PMID:30542360 -3.1.3.18 * thermoplasma acidophilum 19.82 15.685 4 PMID:14555659 -3.1.3.18 * zea mays 99.0 99.0 1 PMID:24232028 -3.1.3.19 * triticum aestivum 21.0 21.0 1 * -3.1.3.19 * vigna radiata 21.0 21.0 1 * -3.1.3.2 * agaricus bisporus 225.0 225.0 1 PMID:15188886 -3.1.3.2 * allium sativum 168.0 168.0 1 PMID:12721447 -3.1.3.2 * amoeba proteus 2.712 1.4575 2 * -3.1.3.2 * arabidopsis thaliana 421.0 74.05 6 PMID:16963519;PMID:19633233 -3.1.3.2 * arachis hypogaea 54.7 30.5 5 PMID:7549937 -3.1.3.2 * aspergillus ficuum 150.0 150.0 1 PMID:20144543 -3.1.3.2 * aspergillus nidulans 1960.0 1960.0 1 PMID:4552990 -3.1.3.2 * aspergillus niger 361.3 185.48000000000002 2 PMID:17455790 -3.1.3.2 * aspergillus phoenicis 26.4 26.4 1 * -3.1.3.2 * bos taurus 100.0 41.1 4 PMID:10027907;PMID:3027088;PMID:4975223;PMID:7212711;PMID:952892 -3.1.3.2 * brassica nigra 1225.0 1225.0 1 PMID:1897950 -3.1.3.2 * burkholderia gladioli 103.9 103.9 1 PMID:24713147 -3.1.3.2 * candida albicans 78.7 78.7 1 PMID:4633344 -3.1.3.2 * carthamus oxyacanthus 16.98 16.98 1 PMID:36481331 -3.1.3.2 * cicer arietinum 1.17 1.17 1 * -3.1.3.2 * clostridium perfringens 98.3 52.1 5 PMID:19363079 -3.1.3.2 * corylus avellana 239.0 117.0 3 PMID:15048567 -3.1.3.2 * cullen corylifolium 264200.0 264200.0 1 * -3.1.3.2 * cutibacterium acnes 28.8 28.8 1 PMID:7420057 -3.1.3.2 * dioscorea cayenensis-rotundata 1600.0 1350.0 2 * -3.1.3.2 * drosophila melanogaster 1030.0 1030.0 1 PMID:6776114 -3.1.3.2 * eimeria tenella 1.57 1.57 1 PMID:3371447 -3.1.3.2 * entamoeba histolytica 0.012 0.012 1 PMID:10779571 -3.1.3.2 * francisella tularensis 0.0159 0.00805 2 PMID:15964202;PMID:8631917 -3.1.3.2 * gallus gallus 18.0 18.0 1 PMID:9226888 -3.1.3.2 * glycine max 845.0 13.700000000000001 6 PMID:15061079;PMID:15278453 -3.1.3.2 * gossypium hirsutum 1444.0 1444.0 1 * -3.1.3.2 * homo sapiens 387.0 161.15 8 PMID:10027907;PMID:11838317;PMID:16620768;PMID:2268668;PMID:2775236;PMID:6090300;PMID:7212711;PMID:8288593 -3.1.3.2 * hordeum vulgare 8.7 8.7 1 PMID:2294973 -3.1.3.2 * ipomoea batatas 545.0 433.4 2 PMID:16623702 -3.1.3.2 * juglans regia 31.35 31.35 1 * -3.1.3.2 * labeo rohita 35.6 6.58 3 PMID:18451497 -3.1.3.2 * lactiplantibacillus pentosus 13.42 7.42 2 PMID:15610436 -3.1.3.2 * landoltia punctata 156.0 128.0 4 PMID:15631514 -3.1.3.2 * latilactobacillus curvatus 1675.0 1675.0 1 * -3.1.3.2 * legionella micdadei 0.63 0.63 1 PMID:2998281 -3.1.3.2 * lens culinaris 10.0 10.0 1 PMID:10446377 -3.1.3.2 * lupinus luteus 895.0 895.0 1 PMID:9300805 -3.1.3.2 * mucor hiemalis 46.7 25.0 2 PMID:17889394 -3.1.3.2 * musa cavendishii 745.0 745.0 1 PMID:11800388 -3.1.3.2 * neurospora crassa 143.0 143.0 1 PMID:5545084 -3.1.3.2 * nicotiana tabacum 1998.0 1246.0 2 PMID:18762304;PMID:22698754 -3.1.3.2 * opuntia megacantha 8.78 8.78 1 PMID:32454111 -3.1.3.2 * oryctolagus cuniculus 12.0 6.35 2 PMID:736900 -3.1.3.2 * oryza sativa 107.52 107.52 1 PMID:27335351 -3.1.3.2 * paracoccus denitrificans 1.61 1.61 1 PMID:197075 -3.1.3.2 * penicillium chrysogenum 364.0 364.0 1 PMID:1909579 -3.1.3.2 * phaseolus vulgaris 383.3 106.3 5 PMID:12054466;PMID:15247223;PMID:15331086;PMID:17258469 -3.1.3.2 * pinctada fucata 0.73 0.655 2 PMID:16380281 -3.1.3.2 * pseudomonas aeruginosa 1.0 1.0 1 PMID:3148109 -3.1.3.2 * rattus norvegicus 2620.0 291.0 6 PMID:2732218;PMID:3085593;PMID:3235452;PMID:6706919;PMID:8063012;PMID:8430088 -3.1.3.2 * ribes nigrum 10.39 10.39 1 * -3.1.3.2 * ricinus communis 230.0 230.0 1 PMID:15646022 -3.1.3.2 * rumex dentatus 63.0 63.0 1 * -3.1.3.2 * saccharomyces cerevisiae 221.2 63.75 6 PMID:2407294 -3.1.3.2 * schizosaccharomyces pombe 412.0 343.5 2 PMID:238577;PMID:3536917 -3.1.3.2 * senna occidentalis 17.53 14.61 3 * -3.1.3.2 * sinorhizobium meliloti 70.0 70.0 1 PMID:11685369 -3.1.3.2 * solanum lycopersicum 940.0 620.0 3 PMID:12473124;PMID:14521509 -3.1.3.2 * staphylococcus aureus 78.4 78.4 1 PMID:5776528 -3.1.3.2 * sus scrofa 233.0 117.25 2 PMID:15519293 -3.1.3.2 * tetrahymena pyriformis 898.2 898.2 1 * -3.1.3.2 * thermus thermophilus 670000.0 670000.0 1 PMID:20378986 -3.1.3.2 * trichoderma harzianum 12.4 12.4 1 PMID:20364293 -3.1.3.2 * triticum aestivum 605.0 0.5 3 PMID:1898053 -3.1.3.2 * trypanosoma brucei 43.4 43.4 1 PMID:2226816 -3.1.3.2 * ustilago esculenta 359.0 359.0 1 * -3.1.3.2 * vigna aconitifolia 29.6 29.6 1 PMID:23745690 -3.1.3.20 * bos taurus 0.0018 0.0018 1 PMID:4284998 -3.1.3.20 * euglena gracilis 0.02 0.02 1 * -3.1.3.20 * veillonella parvula 0.037 0.037 1 PMID:6271379 -3.1.3.21 * dunaliella salina 6.1 6.1 1 * -3.1.3.21 * dunaliella tertiolecta 0.63 0.49 2 * -3.1.3.21 * phycomyces blakesleeanus 0.8 0.8 1 PMID:2985386 -3.1.3.21 * saccharomyces cerevisiae 49.0 47.5 2 PMID:8662716 -3.1.3.22 * acinetobacter baylyi 103.0 103.0 1 PMID:24800891 -3.1.3.22 * alternaria alternata 0.44 0.44 1 PMID:6782999 -3.1.3.22 * aspergillus niger 0.027 0.027 1 PMID:6782999 -3.1.3.22 * botrytis cinerea 0.048 0.048 1 PMID:6782999 -3.1.3.22 * caloglossa continua 62.5 62.5 1 PMID:14961343 -3.1.3.22 * ceratocystis multiannulata 0.23 0.23 1 PMID:6782999 -3.1.3.22 * cladosporium cladosporioides 0.31 0.31 1 PMID:6782999 -3.1.3.22 * cyberlindnera jadinii 0.006 0.006 1 PMID:6782999 -3.1.3.22 * eimeria tenella 0.2 0.2 1 PMID:2538747 -3.1.3.22 * fusarium graminearum 0.062 0.062 1 PMID:6782999 -3.1.3.22 * neurospora crassa 0.16 0.16 1 PMID:6782999 -3.1.3.22 * penicillium chrysogenum 1792.0 1792.0 1 PMID:179688 -3.1.3.22 * penicillus frequentans 0.28 0.28 1 PMID:6782999 -3.1.3.22 * pyricularia oryzae 0.087 0.087 1 PMID:6782999 -3.1.3.22 * talaromyces islandicus 0.06 0.06 1 PMID:6782999 -3.1.3.22 * thermomyces lanuginosus 0.045 0.045 1 PMID:6782999 -3.1.3.22 * trichothecium roseum 0.1 0.1 1 PMID:6782999 -3.1.3.23 * escherichia acidilactici 7.99 7.99 1 * -3.1.3.23 * escherichia coli 11.42 7.99 3 PMID:6322944 -3.1.3.23 * klebsiella aerogenes 10.88 10.88 1 PMID:6322944 -3.1.3.23 * neisseria meningitidis 7.88 7.845 2 PMID:6322944 -3.1.3.23 * saccharomyces cerevisiae 4.22 4.22 1 PMID:6322944 -3.1.3.24 * anabaena sp. 15.66 15.66 1 PMID:11800389 -3.1.3.24 * daucus carota 1.433 1.433 1 * -3.1.3.24 * oryza sativa 1250.0 1250.0 1 PMID:11050182 -3.1.3.24 * zea mays 0.37 0.37 1 PMID:11050182 -3.1.3.25 * bos taurus 5.0 5.0 1 PMID:2845918 -3.1.3.25 * escherichia coli 3.3 3.3 1 PMID:10747806 -3.1.3.25 * glycine max 375.6 189.985 2 PMID:17241743 -3.1.3.25 * homo sapiens 15.0 15.0 1 PMID:8784438 -3.1.3.25 * methanocaldococcus jannaschii 9.3 9.3 1 PMID:9647837 -3.1.3.25 * rattus norvegicus 0.85 0.85 1 PMID:2999094 -3.1.3.25 * sus scrofa 1.7 1.7 1 PMID:15715947 -3.1.3.25 * thermotoga maritima 442.0 442.0 1 PMID:10508089 -3.1.3.26 * agrocybe pediades 400.0 400.0 1 PMID:11571175 -3.1.3.26 * aspergillus ficuum 179.5 179.5 1 PMID:12804608 -3.1.3.26 * aspergillus niger 5.276 5.276 1 PMID:12653285 -3.1.3.26 * avena sativa 307.0 307.0 1 * -3.1.3.26 * bacillus sp. (in: firmicutes) 36.0 26.0 2 PMID:11594462;PMID:18479345 -3.1.3.26 * bacillus subtilis 25.0 25.0 1 PMID:18543132 -3.1.3.26 * burkholderia sp. a13(2014) 174.1 174.1 1 PMID:25833676 -3.1.3.26 * ceriporia sp. 1040.0 870.0 2 PMID:11571175 -3.1.3.26 * citrobacter amalonaticus 3548.0 3548.0 1 PMID:17657539 -3.1.3.26 * citrobacter braakii 3457.0 3457.0 1 PMID:14514072 -3.1.3.26 * corylus avellana 6.56 6.56 1 PMID:13679091 -3.1.3.26 * cyberlindnera fabianii 185.0 31.65 6 PMID:19664557 -3.1.3.26 * debaryomyces castellii 182.0 157.4 3 PMID:18242101 -3.1.3.26 * enterobacter sp. acss 805.98 805.98 1 PMID:27250653 -3.1.3.26 * escherichia coli 8016.0 3524.0 5 PMID:17524177;PMID:21380516;PMID:33789740;PMID:8387749 -3.1.3.26 * glycine max 0.53 0.53 1 * -3.1.3.26 * lilium longiflorum 0.066 0.066 1 PMID:16665018 -3.1.3.26 * loigolactobacillus coryniformis 202.25 202.25 1 PMID:30171516 -3.1.3.26 * lupinus albus 607.0 539.0 3 PMID:12405788 -3.1.3.26 * pectobacterium wasabiae 1072.0 1072.0 1 PMID:18667849 -3.1.3.26 * penicillium chrysogenum 2860.0 2105.0 2 PMID:25023696 -3.1.3.26 * penicillium oxalicum 447.5 447.5 1 PMID:26377131 -3.1.3.26 * peniophora lycii 1080.0 648.0 2 PMID:11571175;PMID:12659840 -3.1.3.26 * priestia aryabhattai 72.97 72.97 1 PMID:28248011 -3.1.3.26 * rhodotorula mucilaginosa 36.26 36.26 1 PMID:25727311 -3.1.3.26 * shigella sp. cd2 2982.0 1974.5 2 PMID:26808559 -3.1.3.26 * trametes pubescens 1210.0 1210.0 1 PMID:11571175 -3.1.3.26 * typha latifolia 0.096 0.096 1 * -3.1.3.26 * uncultured bacterium 1844.0 1792.0 3 PMID:25588560;PMID:27363471 -3.1.3.26 * vigna radiata var. radiata 1.07 0.8 2 * -3.1.3.26 * xylanibacter ruminicola 1952.0 1952.0 1 PMID:27174428 -3.1.3.26 * yersinia intermedia 3960.0 3960.0 1 PMID:17034758 -3.1.3.26 * yersinia pestis 2344.0 2344.0 1 PMID:18548246 -3.1.3.26 * yersinia rohdei 2456.0 2456.0 1 PMID:18548246 -3.1.3.26 * zea mays 5.67 3.979 2 PMID:12226456;PMID:8240238 -3.1.3.27 * bacillus licheniformis 0.0023 0.0023 1 PMID:175832 -3.1.3.27 * bacillus subtilis 54.7 25.200000000000003 4 PMID:28168443 -3.1.3.27 * escherichia coli 10.1 0.079 10 PMID:1309518;PMID:1323035;PMID:4292860;PMID:6319391 -3.1.3.27 * rattus sp. 0.0017 0.0017 1 PMID:6296050 -3.1.3.27 * saccharomyces cerevisiae 35.0 35.0 1 PMID:2171664 -3.1.3.27 * vigna radiata 0.0004 0.0004 1 PMID:12232283 -3.1.3.29 * homo sapiens 0.633 0.633 1 * -3.1.3.29 * rattus norvegicus 684.0 342.28 2 PMID:16237198 -3.1.3.3 * arabidopsis thaliana 3.0 3.0 1 PMID:10196182 -3.1.3.3 * bos taurus 0.13 0.13 1 PMID:4374244 -3.1.3.3 * gallus gallus 0.018 0.018 1 PMID:13610904 -3.1.3.3 * hydrogenobacter thermophilus 58.0 43.0 2 PMID:22337887 -3.1.3.3 * saccharomyces cerevisiae 17.3 11.3 2 * -3.1.3.3 * thermus thermophilus 2842.0 323.0 3 PMID:30430741 -3.1.3.32 * bos taurus 1.8 1.8 1 PMID:10227382 -3.1.3.32 * omegavirus omega 19.0 19.0 1 PMID:15056675 -3.1.3.33 * escherichia coli 2460.0 2460.0 1 PMID:4289819 -3.1.3.34 * escherichia coli 380.0 380.0 1 PMID:4289819 -3.1.3.35 * bacillus subtilis 113.0 113.0 1 PMID:99634 -3.1.3.36 * crithidia fasciculata 63.8 31.921999999999997 2 PMID:6271362 -3.1.3.36 * homo sapiens 0.765 0.765 1 PMID:6271223 -3.1.3.37 * arabidopsis thaliana 0.224 0.224 1 PMID:15849430 -3.1.3.37 * chlamydomonas sp. w80 7.15 7.15 1 PMID:15849430 -3.1.3.37 * cyberlindnera jadinii 11.5 11.5 1 PMID:237192;PMID:4329855 -3.1.3.37 * spinacia oleracea 70.0 36.75 2 PMID:3032163 -3.1.3.37 * triticum aestivum 4.25 4.25 1 PMID:6296616 -3.1.3.37 * zea mays 28.6 28.6 1 PMID:6263905 -3.1.3.38 * saccharum sp. 740.0 740.0 1 PMID:10970181 -3.1.3.38 * spinacia oleracea 10.8 5.9 2 PMID:16657823;PMID:16661597 -3.1.3.4 * acholeplasma laidlawii 12.78 12.78 1 PMID:9408176 -3.1.3.4 * homo sapiens 0.1175 0.00285 3 PMID:17555747 -3.1.3.4 * momordica charantia 312.0 312.0 1 PMID:25203006 -3.1.3.4 * parageobacillus toebii 33.3 33.3 1 PMID:19060391 -3.1.3.4 * rattus norvegicus 165.0 10.32 3 PMID:238959;PMID:6087797;PMID:8948459 -3.1.3.4 * saccharomyces cerevisiae 5.6 3.7750000000000004 4 PMID:17910939;PMID:1995619;PMID:6091767 -3.1.3.4 * sus scrofa 15.8 15.8 1 PMID:1334090 -3.1.3.41 * canis lupus familiaris 0.002 0.002 1 PMID:15670149 -3.1.3.41 * macrobrachium olfersii 123.6 123.6 1 PMID:16529963 -3.1.3.41 * rattus norvegicus 0.127 0.0805 2 PMID:16153614;PMID:18198990 -3.1.3.43 * bos taurus 2.3 2.3 1 PMID:3535883 -3.1.3.43 * rattus norvegicus 0.0066 0.0047 10 PMID:17018773 -3.1.3.44 * rattus norvegicus 871.0 526.0 2 PMID:2860106;PMID:6257718 -3.1.3.45 * escherichia coli 15.6 15.6 1 PMID:6246070 -3.1.3.46 * bos taurus 20.0 20.0 1 * -3.1.3.46 * rattus norvegicus 20.0 1.4e-05 3 PMID:15994045 -3.1.3.46 * spinacia oleracea 1650.0 1650.0 1 PMID:11856361 -3.1.3.47 * rattus norvegicus 21480.0 850.0 6 PMID:6260210;PMID:6330255;PMID:6631216 -3.1.3.48 * bdellovibrio bacteriovorus 310.8 0.17 8 PMID:24718691 -3.1.3.48 * bos taurus 47.0 23.54875 2 PMID:3034101;PMID:9635250 -3.1.3.48 * homo sapiens 32300.0 42.7 7 PMID:12112018;PMID:25462809;PMID:2834386;PMID:2844226;PMID:2851993;PMID:8430079 -3.1.3.48 * metarhizium anisopliae 8.681 4.3629999999999995 2 PMID:16926509 -3.1.3.48 * rattus norvegicus 16.2 12.6 2 PMID:15802228;PMID:1918076 -3.1.3.48 * shewanella sp. 73.3 73.3 1 PMID:12761186 -3.1.3.48 * staphylococcus aureus 33.6 17.5 2 PMID:12193638 -3.1.3.48 * synechocystis sp. 0.084 0.07500000000000001 2 PMID:16109928 -3.1.3.48 * thermus thermophilus 5.02 5.02 1 PMID:19657570 -3.1.3.48 * yersinia enterocolitica 1233.0 806.0 3 PMID:1429715 -3.1.3.48 * zea mays 580000.0 291055.0 2 PMID:22529284 -3.1.3.5 * arachis hypogaea 700.0 385.7 4 * -3.1.3.5 * bacillus sp. (in: firmicutes) 57.3 57.3 1 * -3.1.3.5 * bacillus subtilis 0.0245 0.0245 1 PMID:27907199 -3.1.3.5 * bos taurus 300.0 153.5 2 PMID:12608891;PMID:9687019 -3.1.3.5 * cavia porcellus 40.4 40.4 1 PMID:2986711 -3.1.3.5 * columba livia 35.8 20.064999999999998 2 PMID:15940349;PMID:2344353 -3.1.3.5 * danio rerio 0.029 0.029 1 PMID:15465666 -3.1.3.5 * dosidicus gigas 5.15 2.5777 2 * -3.1.3.5 * escherichia coli 592.5 1.32 15 PMID:15489502;PMID:6275004 -3.1.3.5 * gadus macrocephalus 828.0 828.0 1 * -3.1.3.5 * gallus gallus 37.2 37.2 1 PMID:945752 -3.1.3.5 * helicobacter pylori 0.179 0.179 1 PMID:14680961 -3.1.3.5 * homo sapiens 94.0 17.1 3 PMID:11133996;PMID:1998727;PMID:9211338 -3.1.3.5 * mus musculus 0.017 0.017 1 PMID:4721620 -3.1.3.5 * ophiocordyceps sinensis 11.25 11.25 1 PMID:31899296 -3.1.3.5 * oryctolagus cuniculus 71.0 40.5 2 PMID:9636049 -3.1.3.5 * phaseolus vulgaris 4.1 3.4 6 PMID:32024086 -3.1.3.5 * pseudomonas aeruginosa 3.14 3.14 1 PMID:15808744 -3.1.3.5 * rattus norvegicus 175.0 21.5 7 PMID:16480902;PMID:1786854;PMID:4444531;PMID:6260203;PMID:6284244;PMID:8764609 -3.1.3.5 * rhipicephalus microplus 38.8 38.8 1 PMID:2539105 -3.1.3.5 * saccharomyces cerevisiae 16600.0 4.1 5 * -3.1.3.5 * salinivibrio costicola 6.0 6.0 1 PMID:6163762 -3.1.3.5 * sebastes inermis 261.0 144.5 2 * -3.1.3.5 * shewanella amazonensis 184.6 184.6 1 PMID:30764715 -3.1.3.5 * streptomyces sp. ne5-10 7.67 7.67 1 PMID:36820897 -3.1.3.5 * streptomyces sp. y2f8-2 27.1 27.1 1 PMID:36820897 -3.1.3.5 * sus scrofa 0.43 0.43 1 PMID:8619879 -3.1.3.5 * torpedo marmorata 31.26 31.26 1 PMID:2822031 -3.1.3.5 * vibrio parahaemolyticus 1400.0 3.13 8 PMID:2546926;PMID:2835422 -3.1.3.5 * zea mays 0.73 0.73 1 * -3.1.3.50 * malus domestica 89.8 89.8 1 * -3.1.3.51 * sus scrofa 2.59 2.59 1 PMID:9565603 -3.1.3.52 * bos taurus 22.86 1.2839999999999998 4 PMID:2853819;PMID:3031042;PMID:3455764;PMID:6589597 -3.1.3.53 * badhamia polycephala 0.028 0.028 1 PMID:20388117 -3.1.3.53 * meleagris gallopavo 4.0 1.84 3 PMID:2842609;PMID:6304072 -3.1.3.53 * rattus norvegicus 0.00121 0.00102 3 PMID:18094148 -3.1.3.56 * bos taurus 175.0 25.9 3 PMID:1312931;PMID:2540972;PMID:8110204 -3.1.3.56 * canis lupus familiaris 0.089 0.089 1 * -3.1.3.56 * frog 0.0006 0.0006 1 PMID:2845956 -3.1.3.56 * homo sapiens 191.0 3.2 5 PMID:17537645;PMID:2542294;PMID:6285891;PMID:8110204;PMID:8662625 -3.1.3.56 * oryctolagus cuniculus 0.02 0.00385 4 PMID:2845956 -3.1.3.56 * rattus norvegicus 15.2 8.129999999999999 2 PMID:2826417 -3.1.3.56 * sus scrofa 2.54 2.54 1 PMID:8185320 -3.1.3.57 * bos taurus 12.4 12.4 1 PMID:2824473 -3.1.3.57 * rattus norvegicus 0.052 0.052 1 PMID:3039989 -3.1.3.58 * lacticaseibacillus casei 0.154 0.154 1 PMID:2993253 -3.1.3.58 * thermotoga maritima 2.63 2.63 1 PMID:15808744 -3.1.3.59 * tetrahymena pyriformis 0.0164 0.0159 3 PMID:10750839 -3.1.3.6 * crithidia luciliae 2310.0 2310.0 1 PMID:2158995 -3.1.3.6 * escherichia coli 22.4 12.1 7 PMID:15489502 -3.1.3.6 * hordeum vulgare 375.0 375.0 1 PMID:16665113 -3.1.3.6 * leishmania donovani 2345.0 2086.0 2 PMID:1322126;PMID:1857379 -3.1.3.6 * tricholoma matsutake 7900.0 7900.0 1 PMID:20057129 -3.1.3.60 * allium cepa 53.0 53.0 1 * -3.1.3.60 * brassica nigra 1225.0 802.5 2 PMID:16666836;PMID:1897950 -3.1.3.60 * vigna radiata 1.4 1.225 2 PMID:16667434;PMID:16668551 -3.1.3.62 * gallus gallus 0.7 0.7 1 PMID:16759730 -3.1.3.62 * homo sapiens 0.009 0.009 1 PMID:18413611 -3.1.3.62 * rattus norvegicus 4.66 4.475 2 PMID:1653239;PMID:7832765 -3.1.3.63 * nicotiana tabacum 0.2612 0.2612 1 PMID:16666827 -3.1.3.63 * phaseolus vulgaris 6.1 3.905 2 * -3.1.3.67 * rattus norvegicus 6.7 6.7 1 PMID:17562371 -3.1.3.71 * methanocaldococcus jannaschii 48.0 48.0 1 PMID:11589710 -3.1.3.72 * lilium longiflorum 56.0 0.019 5 PMID:16198125;PMID:16665018;PMID:7846160 -3.1.3.72 * shigella sp. cd2 2982.0 1974.5 2 PMID:26808559 -3.1.3.72 * sporolactobacillus laevolacticus 12.69 7.3149999999999995 2 PMID:16967265 -3.1.3.74 * homo sapiens 5.3 1.4 4 PMID:1322411;PMID:14522954;PMID:7625842;PMID:8125926 -3.1.3.74 * nicotiana tabacum 0.97 0.8 3 PMID:30471733 -3.1.3.74 * paenibacillus thiaminolyticus 20.0 7.0 3 PMID:16336194 -3.1.3.74 * sinorhizobium meliloti 105.0 73.5 2 PMID:16377884 -3.1.3.75 * arabidopsis thaliana 3.67 2.075 2 PMID:22024570 -3.1.3.75 * homo sapiens 4.96 0.0748 7 PMID:15175005;PMID:16054448 -3.1.3.75 * pseudomonas aeruginosa 142.0 94.2 10 PMID:17106798;PMID:18801468;PMID:20135339;PMID:21515416 -3.1.3.76 * homo sapiens 0.53 0.25 5 PMID:12574510;PMID:16414022 -3.1.3.76 * rattus norvegicus 1.05 0.9199999999999999 4 PMID:16414022 -3.1.3.77 * klebsiella oxytoca 0.179 0.00816 3 PMID:8227040 -3.1.3.77 * klebsiella pneumoniae 21.0 21.0 1 PMID:8227039 -3.1.3.78 * salmonella enterica subsp. enterica serovar typhimurium 6.3e-06 3.5e-06 2 PMID:16153243 -3.1.3.78 * shigella flexneri 0.061 0.01765 6 PMID:12356723 -3.1.3.8 * agaricus bisporus 14.61 14.61 1 PMID:15675798 -3.1.3.8 * arabidopsis thaliana 10.0 10.0 1 PMID:19633233 -3.1.3.8 * aspergillus ficuum 216.0 164.8 4 PMID:12659840;PMID:12804608;PMID:20144543 -3.1.3.8 * aspergillus niger 870.0 65.94 6 PMID:12653285;PMID:17958557;PMID:18446871;PMID:9449782 -3.1.3.8 * aspergillus oryzae 60.63 60.63 1 PMID:28527994 -3.1.3.8 * bacillus amyloliquefaciens 27.0 21.15 2 PMID:25613522;PMID:26188308 -3.1.3.8 * bacillus cereus 19.42 19.42 1 PMID:37020067 -3.1.3.8 * bacillus licheniformis 296.5 162.6 2 PMID:33220867 -3.1.3.8 * bacillus sp. (in: firmicutes) 36.0 16.0 9 PMID:11594462;PMID:18479345;PMID:21707924;PMID:22112406 -3.1.3.8 * bacillus subtilis 79.3 9.95 12 PMID:18543132;PMID:20601512;PMID:27222743;PMID:6286590;PMID:9603817 -3.1.3.8 * bacillus subtilis subsp. subtilis 8.61 8.61 1 PMID:30015561 -3.1.3.8 * bryoria fuscescens 0.000183 0.000183 1 PMID:25963718 -3.1.3.8 * burkholderia sp. a13(2014) 174.1 174.1 1 PMID:25833676 -3.1.3.8 * citrobacter braakii 3457.0 3457.0 1 PMID:14514072 -3.1.3.8 * citrobacter gillenii 1577.0 1577.0 1 PMID:33347540 -3.1.3.8 * cladonia portentosa 1.7e-07 1.7e-07 1 PMID:25963718 -3.1.3.8 * corylus avellana 6.56 6.56 1 PMID:13679091 -3.1.3.8 * cronobacter turicensis 1705.0 1705.0 1 PMID:36195031 -3.1.3.8 * debaryomyces castellii 182.0 157.4 3 PMID:18046551;PMID:18242101 -3.1.3.8 * dendroctonus frontalis 4175.0 4175.0 1 PMID:26536874 -3.1.3.8 * enterobacter sp. acss 805.98 805.98 1 PMID:27250653 -3.1.3.8 * escherichia coli 53.13 53.13 1 PMID:18162589 -3.1.3.8 * evernia prunastri 0.00015 0.00015 1 PMID:25963718 -3.1.3.8 * hypogymnia physodes 1.67e-05 1.67e-05 1 PMID:25963718 -3.1.3.8 * janthinobacterium sp. 35.0 35.0 1 PMID:21562981 -3.1.3.8 * klebsiella oxytoca 45.3 45.3 1 * -3.1.3.8 * klebsiella sp. 169.0 115.75 2 PMID:14727093;PMID:2162321 -3.1.3.8 * kodamaea ohmeri 823.3 468.95 2 PMID:18040741 -3.1.3.8 * lactiplantibacillus plantarum 1865.2 306.40999999999997 4 PMID:32919432;PMID:35168166 -3.1.3.8 * lobaria pulmonaria 1.67e-05 1.67e-05 1 PMID:25963718 -3.1.3.8 * loigolactobacillus coryniformis 202.25 202.25 1 PMID:30171516 -3.1.3.8 * lupinus albus 607.0 539.0 3 PMID:12405788 -3.1.3.8 * morchella importuna 2384.6 2384.6 1 PMID:29017237 -3.1.3.8 * nicotiana tabacum 361.7 181.222 2 PMID:17897689 -3.1.3.8 * obesumbacterium proteus 310.0 310.0 1 PMID:15251209 -3.1.3.8 * orbilia oligospora 74.71 74.71 1 PMID:32252770 -3.1.3.8 * pantoea agglomerans 23.0 23.0 1 PMID:15648978 -3.1.3.8 * pantoea sp. 3.5.1 5.92 5.92 1 PMID:26209662 -3.1.3.8 * parmelia saxatilis 1.67e-05 1.67e-05 1 PMID:25963718 -3.1.3.8 * pectobacterium carotovorum 792.0 792.0 1 PMID:19884763 -3.1.3.8 * pectobacterium wasabiae 1072.0 1072.0 1 PMID:18667849 -3.1.3.8 * peltigera membranacea 8.3e-06 8.3e-06 1 PMID:25963718 -3.1.3.8 * penicillium chrysogenum 2860.0 2105.0 2 PMID:25023696 -3.1.3.8 * penicillium oxalicum 447.5 447.5 1 PMID:26377131 -3.1.3.8 * penicillium sp. 32.76 32.76 1 PMID:20826112 -3.1.3.8 * platismatia glauca 2.75e-05 2.75e-05 1 PMID:25963718 -3.1.3.8 * priestia aryabhattai 72.97 72.97 1 PMID:28248011 -3.1.3.8 * pseudevernia furfuracea 0.000133 0.000133 1 PMID:25963718 -3.1.3.8 * ramalina calicaris 2.5e-05 2.5e-05 1 PMID:25963718 -3.1.3.8 * ramalina farinacea 2e-05 2e-05 1 PMID:25963718 -3.1.3.8 * ramalina fraxinea 8.3e-06 8.3e-06 1 PMID:25963718 -3.1.3.8 * raoultella terrigena 205.0 205.0 1 PMID:9169005 -3.1.3.8 * rhizopus microsporus 2285.0 2285.0 1 PMID:26906117 -3.1.3.8 * rhizopus microsporus var. oligosporus 54.0 43.5 2 * -3.1.3.8 * rhodotorula mucilaginosa 36.26 36.26 1 PMID:25727311 -3.1.3.8 * serratia sp. (in: enterobacteria) 144.0 5.04 4 PMID:21853317 -3.1.3.8 * shigella sp. cd2 2982.0 1974.5 2 PMID:26808559 -3.1.3.8 * streptomyces sp. 2.1 2.1 1 PMID:27132983 -3.1.3.8 * thermothelomyces heterothallicus 1190.0 46.0 3 PMID:26758064;PMID:27697488 -3.1.3.8 * thermothelomyces thermophilus 8000.0 52.4 3 PMID:15063805;PMID:26433599 -3.1.3.8 * uncultured bacterium 1844.0 1792.0 3 PMID:25588560;PMID:27363471 -3.1.3.8 * usnea subfloridana 0.000133 0.000133 1 PMID:25963718 -3.1.3.8 * xylanibacter ruminicola 1952.0 1952.0 1 PMID:27174428 -3.1.3.8 * yersinia enterocolitica 3.28 3.28 1 PMID:21380516 -3.1.3.8 * yersinia frederiksenii 428.0 428.0 1 PMID:19378262 -3.1.3.8 * yersinia kristensenii 2656.0 2656.0 1 * -3.1.3.8 * yersinia mollaretii 0.25 0.25 1 PMID:30141080 -3.1.3.8 * yersinia pestis 2344.0 2344.0 1 PMID:18548246 -3.1.3.8 * yersinia rohdei 2456.0 2456.0 1 PMID:18548246 -3.1.3.9 * homo sapiens 136.0 0.44115000000000004 12 PMID:12093795;PMID:15542400;PMID:18337460;PMID:20302380;PMID:6291517 -3.1.3.9 * marmota monax 0.114 0.0675 2 PMID:16581304 -3.1.3.9 * mus musculus 60.14 0.272 3 PMID:15661744;PMID:34952005 -3.1.3.9 * oryctolagus cuniculus 17.6 9.555000000000001 2 PMID:6249677;PMID:6293458 -3.1.3.9 * rattus norvegicus 124.0 7.85 9 PMID:12757934;PMID:1327763;PMID:169241;PMID:17412326;PMID:2835062 -3.1.3.93 * nicotiana tabacum 37.6 37.6 1 PMID:22790939 -3.1.3.99 * plasmodium falciparum 3.2 0.07 3 PMID:32591529 -3.1.3.99 * saccharomyces cerevisiae 102.5 51.278 2 PMID:8141771 -3.1.30.1 * aspergillus oryzae 266.0 14.95 12 PMID:171268;PMID:6272646 -3.1.30.1 * homo sapiens 0.01 0.01 1 PMID:620006 -3.1.30.1 * lathyrus oleraceus 8.3 8.3 1 PMID:3036008 -3.1.30.1 * mus musculus 7.7 7.7 1 PMID:3027656 -3.1.30.1 * neurospora crassa 810.0 810.0 1 PMID:6154864 -3.1.30.1 * penicillium melinii 41250.0 41250.0 1 PMID:21647618 -3.1.30.2 * mycolicibacterium smegmatis 0.315 0.315 1 PMID:16584627 -3.1.31.1 * staphylococcus aureus 2000.0 2000.0 1 PMID:20492646 -3.1.31.1 * staphylococcus sp. 2553.0 1642.5 2 PMID:10876165;PMID:20415411 -3.1.4.1 * aspergillus niger 3230.0 3230.0 1 * -3.1.4.1 * avena sativa 0.183 0.183 1 PMID:4394093 -3.1.4.1 * badhamia polycephala 0.169 0.169 1 PMID:3017212 -3.1.4.1 * beta vulgaris 125.2 125.2 1 PMID:4333586 -3.1.4.1 * bos taurus 47.7 16.0 3 PMID:191060;PMID:8387370 -3.1.4.1 * daucus carota 253.3 253.3 1 PMID:4313739 -3.1.4.1 * flammulina velutipes 7.65 7.65 1 * -3.1.4.1 * homo sapiens 5.08 0.47 5 PMID:14490780;PMID:2822685;PMID:8275552;PMID:9722024 -3.1.4.1 * hordeum vulgare 8570.0 51.8 3 PMID:12618047;PMID:7687182 -3.1.4.1 * lactobacillus acidophilus 13.4 13.4 1 PMID:4391535 -3.1.4.1 * lupinus luteus 0.9 0.9 1 PMID:6309793 -3.1.4.1 * mus musculus 0.0034 0.00245 2 PMID:19305400 -3.1.4.1 * rattus norvegicus 411.0 1.2 7 PMID:14490780;PMID:4294333;PMID:7532398;PMID:9462844 -3.1.4.1 * sus scrofa 15.5 15.5 1 PMID:14490779 -3.1.4.11 * amycolatopsis sp. nt115 6.19 6.19 1 PMID:37015872 -3.1.4.11 * glycine max 12.6 12.6 1 PMID:12132576 -3.1.4.11 * homo sapiens 200.0 136.0 4 PMID:1332858;PMID:1333955;PMID:2829827 -3.1.4.11 * listeria monocytogenes 1430.0 146.0 28 PMID:19281241 -3.1.4.11 * mus musculus 65.0 1.3 6 PMID:14701816;PMID:3493241 -3.1.4.11 * mytilus galloprovincialis 0.019 0.015 2 PMID:11126770 -3.1.4.11 * phaseolus vulgaris 0.027 0.027 1 PMID:19140892 -3.1.4.11 * rattus norvegicus 204.1 20.185 4 PMID:1646858;PMID:1651335 -3.1.4.11 * sus scrofa 0.28 0.08499999999999999 6 PMID:4377210 -3.1.4.12 * bacillus cereus 0.49 0.475 2 PMID:14741383 -3.1.4.12 * bos taurus 0.9334 0.051 9 PMID:10713073;PMID:10936181;PMID:19968763 -3.1.4.12 * danio rerio 5.42e-05 2.64e-05 5 PMID:18678863 -3.1.4.12 * helicobacter pylori 0.014 0.014 1 PMID:10769141 -3.1.4.12 * homo sapiens 92.8 7.33 9 PMID:10563319;PMID:12631268;PMID:12801930;PMID:17923876;PMID:18989780;PMID:2541739;PMID:2825797 -3.1.4.12 * kionochaeta sp. 0.13 0.13 1 PMID:27444331 -3.1.4.12 * pseudomonas sp. 33.0 33.0 1 PMID:11751833 -3.1.4.12 * rasamsonia emersonii 0.13 0.13 1 PMID:27444331 -3.1.4.12 * rattus norvegicus 146.7 3.141 6 PMID:10563320;PMID:11861674;PMID:16255717;PMID:18001268 -3.1.4.12 * streptomyces griseocarneus 98.4 49.323 2 PMID:19716517 -3.1.4.13 * gallus gallus 3.83 3.83 1 PMID:14284710 -3.1.4.16 * bacillus sp. (in: firmicutes) 12.93 12.93 1 * -3.1.4.16 * escherichia coli 17.9 3.87 10 PMID:15210699 -3.1.4.16 * fusarium culmorum 0.025 0.025 1 PMID:10817902 -3.1.4.16 * solanum lycopersicum 100.0 100.0 1 PMID:10677447 -3.1.4.17 * bos taurus 1.33 0.845 2 PMID:16422208;PMID:6313664 -3.1.4.17 * myxococcus xanthus 0.0309 0.0258 2 PMID:21317337 -3.1.4.17 * sinorhizobium fredii 0.727 0.4115 2 * -3.1.4.2 * bacillus pumilus 0.004 0.004 1 PMID:6319195 -3.1.4.2 * bos taurus 0.598 0.347 2 PMID:8139761 -3.1.4.2 * doryteuthis pealeii 0.001 0.001 1 PMID:181064;PMID:8529026 -3.1.4.2 * escherichia coli 325.0 325.0 1 PMID:2829735 -3.1.4.2 * mus musculus 2.0 2.0 1 PMID:20576599 -3.1.4.2 * oryza sativa 0.126 0.108 3 PMID:30307043 -3.1.4.2 * rattus sp. 5.72 0.1 11 PMID:1651840;PMID:181064;PMID:2555219;PMID:4305487;PMID:6299281;PMID:7862100;PMID:8529026 -3.1.4.2 * serratia plymuthica 93.0 93.0 1 PMID:13143024 -3.1.4.3 * bacillus cereus 13190.0 1260.0 4 PMID:17115205;PMID:4216738;PMID:4353386 -3.1.4.3 * brassica napus 0.002 0.002 1 PMID:16644231 -3.1.4.3 * clostridium perfringens 2100.0 1620.0 3 PMID:191435;PMID:6268935;PMID:6329100 -3.1.4.3 * homo sapiens 1050000.0 836.0 4 PMID:8780678;PMID:9056492;PMID:9360711 -3.1.4.3 * legionella pneumophila 0.029 0.029 1 PMID:3171547 -3.1.4.3 * pseudomonas aeruginosa 1940.0 36.0 7 PMID:12410824;PMID:14962039;PMID:3110070;PMID:3151209;PMID:6811552;PMID:8174749 -3.1.4.3 * pseudomonas chlororaphis subsp. aureofaciens 17.5 17.5 1 PMID:241404 -3.1.4.3 * pseudomonas fluorescens 63.3 63.3 1 PMID:8722307 -3.1.4.3 * rattus norvegicus 3.0 1.34 3 PMID:1577727 -3.1.4.3 * streptomyces hachijoensis 84.6 79.44999999999999 2 PMID:5411 -3.1.4.3 * tetrahymena pyriformis 2.083 2.083 1 PMID:8292995 -3.1.4.3 * trypanosoma brucei 0.00245 0.00245 1 PMID:3782089 -3.1.4.35 * bos taurus 1200.0 610.0 2 PMID:6286681 -3.1.4.35 * mus musculus 1.44 0.720305 2 PMID:11389965 -3.1.4.35 * rattus norvegicus 5.0 2.500006 2 PMID:12135389;PMID:2842633 -3.1.4.37 * bos taurus 2680.0 2300.0 3 PMID:2537684;PMID:6253072;PMID:6258586 -3.1.4.37 * canis lupus familiaris 800.0 800.0 1 PMID:2537684 -3.1.4.37 * cavia porcellus 800.0 800.0 1 PMID:2537684 -3.1.4.37 * chondrichthyes 800.0 403.14 2 PMID:2537684 -3.1.4.37 * danio rerio 130.6 130.6 1 PMID:10098837 -3.1.4.37 * escherichia coli 17.9 3.87 10 PMID:15210699 -3.1.4.37 * gallus gallus 800.0 800.0 1 PMID:2537684 -3.1.4.37 * haemophilus influenzae 800.0 800.0 1 PMID:2537684 -3.1.4.37 * homo sapiens 800.0 800.0 1 PMID:2537684 -3.1.4.37 * mus musculus 800.0 800.0 1 PMID:2537684 -3.1.4.37 * oryctolagus cuniculus 800.0 400.033 2 PMID:2537684 -3.1.4.37 * ovis aries 800.0 800.0 1 PMID:2537684 -3.1.4.37 * rattus norvegicus 800.0 5.739999999999999 6 PMID:15535987;PMID:2537684;PMID:6260166 -3.1.4.37 * sus scrofa 800.0 800.0 1 PMID:2537684 -3.1.4.37 * triticum aestivum 2140.0 1345.0 4 PMID:3654600 -3.1.4.37 * xenopus laevis 800.0 417.5 2 PMID:2537684 -3.1.4.38 * bos taurus 3.2 0.276 3 PMID:23161088;PMID:8923480;PMID:9357012 -3.1.4.38 * streptomyces sanglieri 583.0 432.5 2 PMID:24211038 -3.1.4.39 * homo sapiens 0.135 0.0997 3 PMID:18175805 -3.1.4.39 * mus musculus 0.0919 0.0163 3 PMID:18175805 -3.1.4.39 * oryctolagus cuniculus 0.0027 0.0027 1 PMID:3036238 -3.1.4.39 * rattus norvegicus 0.14 0.00034 9 PMID:17071136;PMID:2848496;PMID:597368 -3.1.4.4 * actinomadura sp. 688.0 688.0 1 * -3.1.4.4 * arabidopsis thaliana 0.0011 0.0011 1 PMID:23738625 -3.1.4.4 * arachis hypogaea 234.0 213.85 2 PMID:16703472;PMID:4642213 -3.1.4.4 * brassica juncea 168.5 168.5 1 PMID:16949665 -3.1.4.4 * brassica juncea var. juncea 253.8 117.8 3 PMID:26057230 -3.1.4.4 * brassica napus 0.15 0.0504 4 PMID:16644231 -3.1.4.4 * brassica oleracea 1492.0 6.18 11 PMID:17451436;PMID:18302938;PMID:23738625;PMID:518840;PMID:8528610 -3.1.4.4 * brassica oleracea var. capitata 7.82 4.09 4 PMID:19251290 -3.1.4.4 * capsella bursa-pastoris 0.0005 0.0005 1 PMID:23738625 -3.1.4.4 * citrus sinensis 0.66 0.66 1 PMID:3688883 -3.1.4.4 * daucus carota 933.0 933.0 1 PMID:11237693 -3.1.4.4 * helianthus annuus 60.0 60.0 1 PMID:21353787 -3.1.4.4 * papaver somniferum 0.5 0.478 2 PMID:16257263 -3.1.4.4 * pseudomonas aeruginosa 2871.0 2108.0 2 PMID:25565226 -3.1.4.4 * rattus norvegicus 17000.0 2.208 4 PMID:11420181;PMID:16527816;PMID:7278682 -3.1.4.4 * shewanella sp. 0.076 0.076 1 PMID:17928713 -3.1.4.4 * streptomyces antibioticus 1437.0 1437.0 1 * -3.1.4.4 * streptomyces chromofuscus 13.0 13.0 1 PMID:12931007 -3.1.4.4 * streptomyces cinnamoneus 468.0 260.0 2 PMID:34585426;PMID:9990122 -3.1.4.4 * streptomyces hiroshimensis 49.48 49.48 1 PMID:36619468 -3.1.4.4 * streptomyces racemochromogenes 374.3 374.3 1 PMID:21082226 -3.1.4.4 * streptomyces sp. 489.7 166.9 9 PMID:18038909;PMID:18302938;PMID:29928916 -3.1.4.4 * streptomyces sp. pmf 4.2 4.2 1 PMID:19241409 -3.1.4.4 * sus scrofa 3.67 3.67 1 PMID:7983063 -3.1.4.4 * vigna unguiculata 27.0 26.0 2 PMID:11161113;PMID:16949301 -3.1.4.41 * corynebacterium pseudotuberculosis 2.65 2.65 1 PMID:5543581 -3.1.4.41 * entamoeba histolytica 84.3 69.3 2 PMID:20350542 -3.1.4.41 * loxosceles boneti 32.5 32.0 2 PMID:16759681 -3.1.4.41 * loxosceles laeta 228.2 142.5 2 PMID:16759681 -3.1.4.41 * loxosceles reclusa 18.3 18.3 1 PMID:16759681 -3.1.4.42 * sus scrofa 322.0 322.0 1 PMID:212014 -3.1.4.45 * homo sapiens 15000.0 4.75 3 PMID:12058031;PMID:7786023 -3.1.4.46 * klebsiella aerogenes 2600.0 120.0 4 PMID:14711669 -3.1.4.46 * oryza sativa 125.8 116.69999999999999 2 PMID:30307043 -3.1.4.49 * gallus gallus 0.000631 0.000631 1 PMID:2826159 -3.1.4.49 * rattus norvegicus 1.1e-07 1.1e-07 1 PMID:2826159 -3.1.4.52 * caulobacter vibrioides 2.42 1.27 2 PMID:15994307 -3.1.4.53 * leishmania mexicana 0.02689 0.02689 1 PMID:10699257 -3.1.4.53 * marchantia polymorpha 0.0058 0.0058 1 PMID:34779957 -3.1.4.54 * mus musculus 0.019 2e-05 3 PMID:15766717;PMID:15949819 -3.1.4.54 * rattus norvegicus 2.6 0.406 3 PMID:14634025;PMID:15949819;PMID:16527816 -3.1.4.56 * methanocaldococcus jannaschii 0.43 0.029 5 PMID:19746965 -3.1.4.61 * methanothermobacter thermautotrophicus 30.5 30.5 1 * -3.1.6.1 * aspergillus oryzae 116.0 116.0 1 PMID:4685274 -3.1.6.1 * eimeria tenella 19.0 19.0 1 PMID:3109387 -3.1.6.1 * flammeovirga pacifica 64.8 45.099999999999994 2 PMID:26282692 -3.1.6.1 * hemicentrotus pulcherrimus 15.0 15.0 1 * -3.1.6.1 * homo sapiens 13400.0 4.82 3 PMID:240321;PMID:33320673 -3.1.6.1 * klebsiella aerogenes 56.0 56.0 1 * -3.1.6.1 * pseudoalteromonas carrageenovora 468.0 468.0 1 PMID:15596366 -3.1.6.1 * pseudomonas aeruginosa 165.0 165.0 1 PMID:7744061 -3.1.6.1 * rattus norvegicus 0.23 0.23 1 PMID:1861083 -3.1.6.1 * serratia marcescens 25.0 25.0 1 PMID:16345546 -3.1.6.1 * sphingomonas sp. 113.0 97.2 3 PMID:14600791 -3.1.6.1 * streptomyces griseorubiginosus 1.14 1.14 1 PMID:7612992 -3.1.6.1 * strongylocentrotus intermedius 1.5 1.5 1 PMID:7396499 -3.1.6.10 * proteus vulgaris 4.75 4.75 1 PMID:5647268 -3.1.6.12 * homo sapiens 93.3 0.003465 6 PMID:17324393;PMID:3435483 -3.1.6.12 * mus musculus 67.53 30.7 5 PMID:15469699;PMID:4084217 -3.1.6.13 * homo sapiens 2730.0 0.6 11 PMID:12393174;PMID:21447345;PMID:23625223;PMID:28593992;PMID:29633336;PMID:37014547;PMID:6950934;PMID:8424762 -3.1.6.13 * rattus norvegicus 0.00725 0.00725 1 PMID:12393174 -3.1.6.14 * homo sapiens 0.922 0.001315 8 PMID:15595925;PMID:3689314;PMID:6428270 -3.1.6.14 * prevotella sp. 0.00086 0.00065 2 PMID:10981693 -3.1.6.17 * pseudomonas syringae 10.9 10.9 1 PMID:6497859 -3.1.6.18 * homo sapiens 6.65 6.65 1 PMID:2497731 -3.1.6.19 * pseudomonas sp. 124.3 124.3 1 PMID:7406859 -3.1.6.19 * rhodococcus ruber 6.9 6.9 1 PMID:12732552 -3.1.6.2 * bos taurus 2.961e-06 2.961e-06 1 PMID:10925212 -3.1.6.2 * homo sapiens 1.556 0.008532 7 PMID:11738554;PMID:12163138;PMID:15056284;PMID:16621525;PMID:37802583;PMID:6580511 -3.1.6.21 * pseudomonas sp. s9 23.25 23.25 1 PMID:21318560 -3.1.6.21 * rhodococcus ruber 6.88 3.469 2 PMID:12732552 -3.1.6.3 * [ruminococcus] torques 0.44 0.32 2 PMID:1398908 -3.1.6.3 * bifidobacterium sp. 0.91 0.505 2 PMID:1398908 -3.1.6.3 * charonia lampas 2.2 2.2 1 PMID:7553 -3.1.6.3 * littorina littorea 0.36 0.36 1 * -3.1.6.3 * prevotella sp. 1.9 1.9 1 * -3.1.6.4 * actinobacillus sp. 0.138 0.138 1 PMID:153151 -3.1.6.4 * homo sapiens 2.68 1.11 5 PMID:1794986;PMID:1953646;PMID:7213753 -3.1.6.6 * pseudomonas aeruginosa 0.262 0.262 1 PMID:4196744 -3.1.6.6 * pseudomonas nitroreducens 0.0714 0.0714 1 PMID:13919191 -3.1.6.8 * acipenser gueldenstaedtii 4.316 3.9745 2 PMID:15581789 -3.1.6.8 * gallus gallus 1.5 1.5 1 PMID:5073233 -3.1.6.8 * homo sapiens 2233.0 0.0018 19 PMID:11295292;PMID:16011900;PMID:16076251;PMID:16087406;PMID:16613739 -3.1.6.8 * oryctolagus cuniculus 135.0 88.5 2 PMID:19014;PMID:40545 -3.1.6.8 * sus scrofa 60.0 24.0 3 PMID:17474085 -3.1.7.11 * ocimum basilicum 104.1 104.1 1 PMID:14657409 -3.1.7.13 * glycine max 20.66 20.66 1 PMID:34100588 -3.1.7.2 * streptococcus dysgalactiae subsp. equisimilis 52.0 0.58 4 PMID:12003927 -3.1.7.5 * croton stellatopilosus 0.35 0.19499999999999998 2 PMID:16445953 -3.1.7.6 * rattus norvegicus 0.0068 0.0068 1 PMID:7986083 -3.1.8.1 * agrobacterium tumefaciens 168.0 101.0 2 PMID:16686603 -3.1.8.1 * bos taurus 288.0 18.66 6 PMID:21985443;PMID:24563030;PMID:24907040 -3.1.8.1 * brevundimonas diminuta 1.4 0.9834999999999999 2 PMID:27163850 -3.1.8.1 * escherichia coli k-12 35.0 5.0 5 PMID:15294802 -3.1.8.1 * flavobacterium sp. 0.097 0.00015 3 PMID:20132373 -3.1.8.1 * homo sapiens 3840.0 5.15 27 PMID:15772423;PMID:16457617;PMID:16600468;PMID:1673382;PMID:18624774;PMID:18711144;PMID:18952040;PMID:19084484;PMID:19103263;PMID:19548782;PMID:19902382;PMID:21123122;PMID:27838376 -3.1.8.1 * mus musculus 429.0 429.0 1 PMID:7945421 -3.1.8.1 * oryctolagus cuniculus 4.17 4.17 1 PMID:1718413 -3.1.8.1 * pimelobacter simplex 33.0 33.0 1 PMID:10772149 -3.1.8.1 * platynota idaeusalis 8310.0 8310.0 1 PMID:11170316 -3.1.8.1 * plesiomonas sp. 53.8 53.8 1 PMID:15249038 -3.1.8.1 * purpureocillium lilacinum 76.3 76.3 1 * -3.1.8.1 * rattus norvegicus 1370.0 1370.0 1 PMID:9032442 -3.1.8.1 * saccharolobus solfataricus 10.5 0.0022 3 PMID:15909078;PMID:28074318 -3.1.8.1 * scyliorhinus canicula 12.84 6.592 2 PMID:21883041 -3.1.8.1 * sulfolobus acidocaldarius 12.3 12.165 2 PMID:23174457;PMID:29558934 -3.10.1.2 * pseudomonas sp. 160.0 160.0 1 PMID:4209783 -3.11.1.1 * bacillus cereus 13.9 13.9 1 PMID:4989158 -3.11.1.2 * penicillium oxalicum 665.0 665.0 1 PMID:16129582 -3.11.1.3 * variovorax sp. 163.0 163.0 1 PMID:12697754 -3.12.1.1 * thermithiobacillus tepidarius 0.038 0.023 2 * -3.13.1.1 * arabidopsis thaliana 0.0026 0.0026 1 PMID:11073956 -3.13.1.3 * paenibacillus sp. 0.139 0.139 1 PMID:12743754 -3.13.1.3 * rhodococcus erythropolis 26.8 0.1935 4 PMID:12147352;PMID:12801508;PMID:17986771 -3.13.1.4 * advenella mimigardefordensis 4.19 4.19 1 PMID:26057676 -3.13.2.1 * acinetobacter calcoaceticus 0.0163 0.009009999999999999 2 PMID:6428887 -3.13.2.1 * alcaligenes faecalis 3.61 0.034 5 PMID:6428887 -3.13.2.1 * arthrobacter globiformis 0.00931 0.005305000000000001 2 PMID:6428887 -3.13.2.1 * beta vulgaris 2.84 2.84 1 PMID:3135 -3.13.2.1 * bos taurus 12.0 0.5145 6 PMID:3349103;PMID:3657555;PMID:6293581;PMID:659427;PMID:8871889 -3.13.2.1 * candida albicans 0.01 0.01 1 PMID:1125818 -3.13.2.1 * canis lupus familiaris 0.0356 0.017815 2 PMID:1125818 -3.13.2.1 * corynebacterium efficiens 0.352 0.352 1 PMID:18034499 -3.13.2.1 * cyberlindnera jadinii 0.012 0.012 1 PMID:1125818 -3.13.2.1 * dictyostelium discoideum 0.3 0.3 1 PMID:6091559 -3.13.2.1 * gallus gallus 0.0033 0.001675 2 PMID:1125818 -3.13.2.1 * homo sapiens 4.4 1.23 7 PMID:11134963;PMID:16872278;PMID:18211827;PMID:19177456;PMID:4052045 -3.13.2.1 * hordeum vulgare subsp. vulgare 0.0215 0.0215 1 PMID:1125818 -3.13.2.1 * lupinus luteus 3.7 3.7 2 PMID:21137580;PMID:923592 -3.13.2.1 * mesocricetus auratus 1.4 1.4 1 PMID:6639063 -3.13.2.1 * micromonospora faeni 0.0531 0.029805 2 PMID:6428887 -3.13.2.1 * mus musculus 0.3 0.15339999999999998 2 PMID:6293581;PMID:6600937 -3.13.2.1 * mycobacterium avium 0.00855 0.005350000000000001 2 PMID:6428887 -3.13.2.1 * nocardia asteroides 0.00938 0.0053549999999999995 2 PMID:6428887 -3.13.2.1 * nonomuraea angiospora 0.375 0.2054 2 PMID:6428887 -3.13.2.1 * oryctolagus cuniculus 0.0055 0.00279 2 PMID:1125818 -3.13.2.1 * phaseolus vulgaris 0.0615 0.0371 2 PMID:1125818 -3.13.2.1 * plasmodium falciparum 0.11 0.11 1 PMID:11134963 -3.13.2.1 * pseudomonas sp. 0.0384 0.007405 4 PMID:6428887 -3.13.2.1 * pyrococcus furiosus 0.033 0.033 1 PMID:15645450 -3.13.2.1 * pyrococcus horikoshii 0.2122 0.16755 2 PMID:37096382 -3.13.2.1 * rattus norvegicus 5.95 0.04485 8 PMID:1125818;PMID:7305945;PMID:7462216;PMID:952944 -3.13.2.1 * saccharolobus solfataricus 0.165 0.163 3 PMID:10648166;PMID:8329449 -3.13.2.1 * saccharomyces cerevisiae 0.503 0.259 2 PMID:1125818;PMID:4562409 -3.13.2.1 * spinacia oleracea 0.0027 0.0027 1 PMID:1125818 -3.13.2.1 * streptomyces hygroscopicus 0.0513 0.029304999999999998 2 PMID:6428887 -3.13.2.1 * streptomyces netropsis 0.0324 0.017865 2 PMID:6428887 -3.13.2.1 * streptomyces yerevanensis 0.0492 0.026655 2 PMID:6428887 -3.13.2.1 * streptosporangium roseum 0.0747 0.041635 2 PMID:6428887 -3.13.2.1 * trichomonas vaginalis 0.32 0.32 1 PMID:9769247 -3.13.2.1 * zea mays 0.0707 0.0707 1 PMID:1125818 -3.2.1.1 * alcaligenes faecalis 5.33 5.33 1 * -3.2.1.1 * alicyclobacillus acidocaldarius 16.9 16.9 1 PMID:7813489 -3.2.1.1 * alkalimonas amylolytica 7826.0 7826.0 1 PMID:17068753 -3.2.1.1 * anabaena sp. 0.54 0.2702875 2 PMID:19756583 -3.2.1.1 * anoxybacillus beppuensis 10000.0 10000.0 1 PMID:26657843 -3.2.1.1 * anoxybacillus sp. ah1 27065.0 27065.0 1 PMID:27904395 -3.2.1.1 * apis mellifera 4410.0 4410.0 1 * -3.2.1.1 * arthrobacter agilis 60.0 43.980000000000004 2 PMID:27714640 -3.2.1.1 * ascaris suum 7.7 4.32 2 PMID:11833785 -3.2.1.1 * aspergillus flavus 523.0 285.55 2 PMID:29607285 -3.2.1.1 * aspergillus niger 2.2 2.2 1 PMID:18048915 -3.2.1.1 * aspergillus oryzae 627.5 518.75 2 PMID:7663414 -3.2.1.1 * bacillus amyloliquefaciens 4230.0 103.75 5 PMID:18769877;PMID:23923536;PMID:29729336;PMID:32871125;PMID:36857902 -3.2.1.1 * bacillus cereus 44.0 44.0 1 PMID:26657843 -3.2.1.1 * bacillus licheniformis 2902.26 2122.63 2 PMID:20490755;PMID:29233713 -3.2.1.1 * bacillus mojavensis 648.2 648.2 3 PMID:20108054 -3.2.1.1 * bacillus sp. (in: firmicutes) 5009.0 151.7 11 PMID:11282629;PMID:12856195;PMID:20109486;PMID:33827572;PMID:9726872 -3.2.1.1 * bacillus sp. dsh19-1 16.4 16.4 1 PMID:29936543 -3.2.1.1 * bacillus sp. mb6 402.02 336.30499999999995 2 * -3.2.1.1 * bacillus subtilis 4133.0 11.2 9 PMID:15043510;PMID:15866721;PMID:16347662;PMID:16850297 -3.2.1.1 * bacteria 50.0 50.0 1 * -3.2.1.1 * bifidobacterium longum 9.7 9.7 1 PMID:26979859 -3.2.1.1 * brevibacillus laterosporus 75.8 75.8 1 * -3.2.1.1 * carthamus tinctorius 246.5 124.195 2 PMID:19393974 -3.2.1.1 * citrus sinensis 7.986 4.471 2 PMID:19941088 -3.2.1.1 * corallococcus sp. egb 980.0 550.65 2 PMID:29752267 -3.2.1.1 * cryptococcus sp. (in: basidiomycete fungi) 2539.0 2539.0 1 PMID:8836148 -3.2.1.1 * eleusine coracana 1773.0 1500.0 3 PMID:12475615 -3.2.1.1 * fusicoccum sp. 838.9 838.9 1 PMID:17690465 -3.2.1.1 * geobacillus sp. 59.0 7.3999999999999995 4 PMID:19874846;PMID:20094713 -3.2.1.1 * geobacillus sp. k1c 26493.0 26493.0 1 PMID:29864538 -3.2.1.1 * glycine max 384.6 384.6 1 PMID:20655076 -3.2.1.1 * halalkalibacterium halodurans 130.0 74.0 2 PMID:17928706 -3.2.1.1 * haliotis discus discus 0.1 0.1 1 PMID:19135166 -3.2.1.1 * halorubrum xinjiangense 487.5 487.5 2 PMID:23695659 -3.2.1.1 * haloterrigena turkmenica 79.8 79.8 1 PMID:27377461 -3.2.1.1 * heterorhabditis bacteriophora 98.4 98.4 1 PMID:15364283 -3.2.1.1 * homo sapiens 5500.0 110.94 3 PMID:11914097;PMID:30001600 -3.2.1.1 * hordeum vulgare 1900.0 1900.0 1 PMID:11890202 -3.2.1.1 * laceyella sacchari 4215.91 4215.91 1 * -3.2.1.1 * lactobacillus amylovorus 4076.0 4076.0 1 PMID:10919790 -3.2.1.1 * lactococcus lactis 2551.0 2551.0 1 PMID:20890096 -3.2.1.1 * lasiodiplodia theobromae 48.8 48.8 1 * -3.2.1.1 * lathyrus oleraceus 1190.0 1190.0 2 PMID:16667384 -3.2.1.1 * limosilactobacillus fermentum 135.5 135.5 1 * -3.2.1.1 * lysobacter brunescens 371.0 371.0 1 * -3.2.1.1 * microbacterium foliorum 804.88 700.19 2 PMID:29142163 -3.2.1.1 * morimus funereus 1068.0 1068.0 1 PMID:17942357 -3.2.1.1 * mus musculus 229.0 166.95 2 PMID:11329174 -3.2.1.1 * mycothermus thermophilus 5.6 5.6 1 PMID:12743761 -3.2.1.1 * mytilus galloprovincialis 42.0 25.0 2 PMID:16009590 -3.2.1.1 * nocardiopsis sp. 548.0 548.0 1 PMID:17934774 -3.2.1.1 * nocardiopsis sp. b2 1755.0 1755.0 1 PMID:26657843 -3.2.1.1 * paenibacillus sp. ssg-1 122.04 122.04 1 PMID:27108054 -3.2.1.1 * pseudoalteromonas sp. 2-3 141.5 89.1 2 PMID:30496815 -3.2.1.1 * pseudomonas sp. 21.0 21.0 1 PMID:237562 -3.2.1.1 * pseudomonas sp. k6-28-040 135.0 135.0 1 PMID:26657843 -3.2.1.1 * pyrococcus furiosus 3900.0 3644.0 3 PMID:15466542;PMID:17119903;PMID:9293008 -3.2.1.1 * rattus norvegicus 654.0 654.0 1 PMID:3496084 -3.2.1.1 * ruminobacter amylophilus 122.0 122.0 1 PMID:14926 -3.2.1.1 * ruminococcus bromii 384.0 72.5 5 PMID:30836186 -3.2.1.1 * saccharopolyspora sp. a9 1641.0 1641.0 1 PMID:26657843 -3.2.1.1 * saitozyma flava 4.16 4.16 1 PMID:21490699 -3.2.1.1 * streptomyces coelicolor a3 1755.0 1755.0 1 PMID:26657843 -3.2.1.1 * streptomyces fragilis 200.76 200.76 1 PMID:28955647 -3.2.1.1 * sus scrofa 1701.0 1701.0 1 * -3.2.1.1 * tepidimonas fonticaldi 1275.0 1275.0 1 PMID:30928371 -3.2.1.1 * thermoactinomyces vulgaris 120.0 120.0 1 * -3.2.1.1 * thermobifida fusca 61.65 61.65 1 PMID:20495998 -3.2.1.1 * thermomonospora curvata 1086.0 1086.0 1 PMID:21612 -3.2.1.1 * thermomyces dupontii 3101.9 2377.8 10 PMID:30703426 -3.2.1.1 * thermomyces lanuginosus 349.0 349.0 1 * -3.2.1.1 * thermotoga maritima 0.3 0.3 1 PMID:16517673 -3.2.1.1 * thermotoga neapolitana 0.0188 0.0109 3 PMID:19834705 -3.2.1.1 * tulipa gesneriana 464.0 464.0 1 * -3.2.1.1 * uncultured bacterium 148.6 15.6 6 PMID:29159586 -3.2.1.1 * vibrio sp. 327.0 327.0 2 PMID:26657843 -3.2.1.1 * vigna angularis 75.0 69.0 2 PMID:12834286 -3.2.1.1 * wangia sp. c52 146.0 146.0 1 PMID:26657843 -3.2.1.1 * zunongwangia profunda 1633.0 1633.0 1 PMID:26657843 -3.2.1.10 * anoxybacillus gonensis 0.4 0.4 1 PMID:37378888 -3.2.1.10 * anser anser 1.02 1.02 1 PMID:2302412 -3.2.1.10 * bacillus cereus 218.0 218.0 1 * -3.2.1.10 * bacillus sp. f5 34.2 34.2 1 PMID:2346949 -3.2.1.10 * bifidobacterium breve 23.0 3.65 18 PMID:19114534 -3.2.1.10 * homo sapiens 3.1 2.8 3 PMID:12624106;PMID:8924896 -3.2.1.10 * parageobacillus thermoglucosidasius 313.0 9.100000000000001 6 PMID:11834128;PMID:2644230 -3.2.1.10 * saccharomyces cerevisiae 74.0 10.6 22 PMID:24649402 -3.2.1.10 * suncus murinus 14.5 8.08 3 PMID:11341943 -3.2.1.10 * thermoanaerobium sp. 5.19 5.19 1 PMID:3214428 -3.2.1.10 * zalophus californianus 4.5 4.5 1 PMID:6715326 -3.2.1.100 * aeromonas hydrophila 86.5 86.5 1 PMID:7096283 -3.2.1.101 * niallia circulans 1.87 1.1600000000000001 2 PMID:10637300;PMID:811665 -3.2.1.102 * clostridium perfringens 2894.0 2197.0 2 PMID:15618227;PMID:18838121 -3.2.1.102 * streptococcus pneumoniae 0.162 0.162 1 PMID:26847;PMID:6459 -3.2.1.103 * bacteroides fragilis 156.0 156.0 1 * -3.2.1.103 * citrobacter freundii 62.8 32.955 2 PMID:135762;PMID:6783649 -3.2.1.103 * sphingobacterium multivorum 44.0 44.0 1 PMID:6783650 -3.2.1.104 * sinapis alba 0.3621 0.3621 1 * -3.2.1.106 * cricetulus griseus 4.5 4.3 3 PMID:18538603 -3.2.1.106 * saccharomyces cerevisiae 8550.0 3000.0 7 PMID:11971867;PMID:14680956;PMID:17458696;PMID:7014569 -3.2.1.107 * gallus gallus 18.7 18.7 1 PMID:385589 -3.2.1.107 * rattus norvegicus 8.3 8.3 1 PMID:7460918 -3.2.1.108 * homo sapiens 32.0 0.002815 6 PMID:17506819;PMID:6786877 -3.2.1.108 * platyrrhini 450.0 233.05 2 PMID:810166 -3.2.1.108 * rattus norvegicus 22.0 0.0135 16 PMID:17190105;PMID:17512743;PMID:18273561;PMID:5010299 -3.2.1.108 * sus scrofa 18.0 18.0 1 PMID:6814489 -3.2.1.11 * achaetomiella gracilis 12569.0 1960.0 5 * -3.2.1.11 * achaetomiella virescens 1571.0 1571.0 1 * -3.2.1.11 * aerobic bacterium sri 2125 0.03 0.03 1 * -3.2.1.11 * aerobic bacterium sri 2128 0.06 0.06 1 * -3.2.1.11 * anaerobic thermophilic bacterium ab11a 0.12 0.12 1 * -3.2.1.11 * arthrobacter sp. 11.9 11.9 1 PMID:24197466 -3.2.1.11 * ascospirella lutea 493.0 493.0 1 PMID:5091941 -3.2.1.11 * aspergillus carneus 2560.0 2530.0 2 PMID:4622623 -3.2.1.11 * aspergillus subolivaceus 8130.0 4845.0 2 * -3.2.1.11 * bacillus licheniformis 1405.0 1405.0 1 PMID:25881960 -3.2.1.11 * catenovulum sp. 2309.0 2309.0 1 PMID:29414837 -3.2.1.11 * chaetomium erraticum 1106.0 1106.0 1 * -3.2.1.11 * cytophaga sp. 12.7 12.7 1 * -3.2.1.11 * flavobacterium johnsoniae 1.12 0.25 3 PMID:27170214 -3.2.1.11 * flavobacterium sp. m-73 36.5 36.5 1 * -3.2.1.11 * fusarium sp. 123.0 123.0 1 PMID:9501522 -3.2.1.11 * fusarium verticillioides 37.0 37.0 1 PMID:953 -3.2.1.11 * lipomyces starkeyi 1385.0 182.0 5 PMID:18082420;PMID:20075611;PMID:2753042 -3.2.1.11 * paenibacillus sp. 11.9 11.9 1 PMID:26907761 -3.2.1.11 * pochonia chlamydosporia 358.0 358.0 1 PMID:29527454 -3.2.1.11 * purpureocillium lilacinum 3893.0 34.6 5 * -3.2.1.11 * streptococcus mutans 58.0 8.21 3 PMID:21479716;PMID:29806555 -3.2.1.11 * streptococcus mutans ingbritt 762.0 762.0 1 PMID:1461154 -3.2.1.11 * streptococcus sobrinus 14500.0 5329.0 4 PMID:3546141;PMID:7526133;PMID:8021165 -3.2.1.11 * talaromyces aculeatus 1670.0 1000.0 5 PMID:18307270 -3.2.1.11 * talaromyces funiculosus 1898.0 90.0 5 PMID:4731965 -3.2.1.11 * talaromyces minioluteus 1025.0 950.0 3 PMID:12839491;PMID:33901619 -3.2.1.11 * talaromyces pinophilus 14894.0 14894.0 1 PMID:28013394 -3.2.1.11 * talaromyces purpureogenus 218.0 218.0 1 * -3.2.1.11 * thermoanaerobacter pseudethanolicus 7.37 4.45 4 PMID:22561857 -3.2.1.11 * thermoanaerobacter sp. 0.68 0.68 1 * -3.2.1.11 * thermochaetoides thermophila 35.0 25.0 2 * -3.2.1.11 * thermophilic bacterium dp17 0.21 0.21 1 * -3.2.1.111 * prunus dulcis 0.0645 0.03298 2 PMID:18111;PMID:7085666 -3.2.1.112 * mus musculus 0.035 0.035 1 PMID:6468386 -3.2.1.113 * aspergillus phoenicis 34.6 34.6 1 PMID:3600352 -3.2.1.113 * candida albicans 0.1081 0.054400000000000004 2 PMID:19057825 -3.2.1.113 * ricinus communis 3.6e-06 3.6e-06 1 PMID:1832562 -3.2.1.114 * arabidopsis thaliana 6.38 6.38 1 PMID:16460512 -3.2.1.114 * aspergillus phoenicis 38000.0 38000.0 1 PMID:3600352;PMID:3745139 -3.2.1.114 * ginkgo biloba 5.4 5.4 1 PMID:15618626 -3.2.1.114 * rattus norvegicus 7.03 4.925 4 PMID:1885615;PMID:7061502;PMID:863880 -3.2.1.114 * thermotoga maritima 4.2 4.2 1 PMID:16511275 -3.2.1.115 * flavobacterium sp. 66.0 66.0 1 * -3.2.1.115 * microbacterium dextranolyticum 81.0 81.0 1 PMID:37033117 -3.2.1.116 * natronococcus sp. 160.0 160.0 1 PMID:1592801 -3.2.1.117 * prunus serotina 9.9 0.58 5 PMID:16652959;PMID:16652960 -3.2.1.118 * mucor circinelloides 12.26 12.26 1 PMID:9446681 -3.2.1.118 * penicillium aurantiogriseum 1.11 0.685 2 PMID:9446681 -3.2.1.118 * prunus serotina 4.9 3.85 2 PMID:16652959 -3.2.1.119 * vicia sativa subsp. nigra 9.86 8.97 3 PMID:17548373 -3.2.1.120 * aspergillus aculeatus 260.0 260.0 1 PMID:9884411 -3.2.1.120 * aspergillus niger 19.0 1.0 3 PMID:11916668 -3.2.1.120 * aspergillus oryzae 427.0 261.0 8 PMID:26755723;PMID:4019436 -3.2.1.120 * lathyrus oleraceus 1294.0 1294.0 1 PMID:12223734 -3.2.1.120 * oerskovia sp. 85.0 85.0 1 * -3.2.1.121 * pseudomonas aeruginosa 3.8 2.0 3 PMID:3935048 -3.2.1.122 * clostridium acetobutylicum 4.9 4.9 1 PMID:14570887 -3.2.1.122 * fusobacterium mortiferum 2.9 2.285 2 PMID:11882720;PMID:7730284 -3.2.1.122 * klebsiella pneumoniae 4.15 0.05925 46 PMID:11473129;PMID:16636060 -3.2.1.123 * aiptasia sp. 0.0002403 0.0002403 1 PMID:15320336 -3.2.1.123 * bacillus sp. (in: firmicutes) 5.8e-06 5.8e-06 1 PMID:15320336 -3.2.1.123 * cellana sp. 1.18e-05 1.18e-05 1 PMID:15320336 -3.2.1.123 * corynebacterium sp. 227.6 227.6 1 PMID:1315273 -3.2.1.123 * cyanea nozakii 2.52 1.26003735 2 PMID:10882727;PMID:15320336 -3.2.1.123 * entacmaea sp. 0.0002346 0.0002346 1 PMID:15320336 -3.2.1.123 * hydra vulgaris 0.00025 0.00023125 4 PMID:15320336 -3.2.1.123 * marphysa sp. 3.2e-06 3.2e-06 1 PMID:15320336 -3.2.1.123 * meretrix sp. 4.4e-06 4.4e-06 1 PMID:15320336 -3.2.1.123 * prescottella equi 6.44 3.21 5 PMID:28179425 -3.2.1.123 * rhodococcus sp. (in: high g+c gram-positive bacteria) 23.5 23.5 1 PMID:2722847 -3.2.1.123 * rhodococcus sp. m-777 0.61 0.24 3 PMID:28179425 -3.2.1.123 * ruditapes sp. 4.6e-06 4.6e-06 1 PMID:15320336 -3.2.1.125 * rauvolfia serpentina 28.1 25.3 2 PMID:10234858 -3.2.1.126 * agrobacterium tumefaciens 39.0 39.0 1 PMID:9630531 -3.2.1.126 * arabidopsis thaliana 599.0 39.849999999999994 4 PMID:16814332 -3.2.1.126 * cicer arietinum 2.7 2.7 1 PMID:25181 -3.2.1.126 * picea abies 4.5 4.5 1 PMID:27355 -3.2.1.126 * pinus contorta 6.6 6.6 1 PMID:7724669 -3.2.1.127 * aspergillus niger 6.06e-07 6.06e-07 1 PMID:2423086 -3.2.1.127 * bacteroides thetaiotaomicron 0.00083 0.00083 1 PMID:35943155 -3.2.1.127 * phocaeicola vulgatus 0.00089 0.00089 1 PMID:35943155 -3.2.1.129 * escherichia phage k1f 4219.0 4219.0 1 PMID:3546309 -3.2.1.129 * phage e 0.95 0.95 1 PMID:3894684 -3.2.1.131 * amphibacillus xylanus 51.2 51.2 1 PMID:33486119 -3.2.1.131 * geobacillus stearothermophilus 42.0 42.0 1 PMID:11358519 -3.2.1.131 * pseudothermotoga thermarum 57.5 57.5 1 * -3.2.1.131 * saccharophagus degradans 8.3 8.3 1 PMID:33486119 -3.2.1.131 * scheffersomyces stipitis cbs 6054 6.2 3.435 2 PMID:19344716 -3.2.1.131 * thermotoga maritima 0.3 0.162 2 PMID:36175749 -3.2.1.131 * uncultured sulfurovum sp. 0.063 0.038 3 PMID:35503213 -3.2.1.132 * aeromonas sp. 850.0 850.0 1 * -3.2.1.132 * amycolatopsis orientalis 61.4 61.4 1 PMID:1888765 -3.2.1.132 * amycolatopsis sp. 38.8 38.8 1 * -3.2.1.132 * amylomyces rouxii 102.3 72.5 2 * -3.2.1.132 * ananas comosus 444.0 444.0 1 PMID:12137495 -3.2.1.132 * aspergillus fumigatus 8.8 8.195 2 PMID:22878198 -3.2.1.132 * aspergillus oryzae 38.8 28.0 2 PMID:11055393 -3.2.1.132 * bacillus amyloliquefaciens 2380.5 2380.5 1 PMID:32027900 -3.2.1.132 * bacillus cereus 196.0 0.177 3 PMID:10568796;PMID:24444885 -3.2.1.132 * bacillus mojavensis 2663.0 2663.0 1 PMID:34912320 -3.2.1.132 * bacillus sp. (in: firmicutes) 1700.0 93.6 9 PMID:11388456;PMID:15294781;PMID:15500976;PMID:16756348;PMID:19342008;PMID:69 -3.2.1.132 * bacillus sp. ts 566.0 566.0 1 PMID:34349190 -3.2.1.132 * bacillus subtilis 21406.1 10795.45 22 PMID:34409950;PMID:37705423 -3.2.1.132 * bacillus thuringiensis 412.0 214.55 2 PMID:21512238 -3.2.1.132 * bambusa oldhamii 0.753 0.243 3 PMID:22166086 -3.2.1.132 * citrus sinensis 3.411 0.1005 8 PMID:8931350 -3.2.1.132 * enterobacter sp. 5.84 5.84 1 * -3.2.1.132 * fusarium solani 5.7 5.7 1 * -3.2.1.132 * gongronella sp. 82.0 82.0 1 PMID:17983432 -3.2.1.132 * kitasatospora albolonga 100.4 100.4 1 PMID:30827665 -3.2.1.132 * kitasatospora setae 1094.21 1094.21 1 PMID:36905451 -3.2.1.132 * myxobacter sp. al-1 800.0 800.0 1 * -3.2.1.132 * niallia circulans 160.0 86.9 2 * -3.2.1.132 * paenibacillus mucilaginosus 6.03 6.03 1 PMID:30974812 -3.2.1.132 * paenibacillus sp. 1-18 539.95 539.95 1 PMID:36661321 -3.2.1.132 * penicillium oxalicum 60.45 60.45 1 PMID:35262875 -3.2.1.132 * priestia megaterium 163.8 159.3 2 PMID:16348170 -3.2.1.132 * pseudomonas sp. 59.1 51.8 3 PMID:18378219 -3.2.1.132 * pseudomonas sp. a-01 3.9 1.98 2 PMID:18685218 -3.2.1.132 * renibacterium sp. 330.67 330.67 1 PMID:34822467 -3.2.1.132 * renibacterium sp. qd1 335.07 335.07 1 PMID:29155203 -3.2.1.132 * rhodotorula toruloides 200.0 200.0 1 * -3.2.1.132 * serratia marcescens 7.0 0.093 4 PMID:18420186 -3.2.1.132 * streptomyces griseus 89.6 2.76 3 PMID:1514694;PMID:20100524;PMID:3147359 -3.2.1.132 * streptomyces hygroscopicus 988.0 988.0 1 PMID:35173697 -3.2.1.132 * streptomyces sp. 105.0 59.349999999999994 4 PMID:24041306;PMID:371;PMID:7487871 -3.2.1.132 * streptomyces sp. n174 52.9 52.9 1 PMID:19143844 -3.2.1.132 * sus scrofa 742.6 733.5 3 PMID:12568570 -3.2.1.132 * talaromyces islandicus 10.0 10.0 1 * -3.2.1.132 * trichoderma viride 0.402 0.402 1 * -3.2.1.133 * bacillus licheniformis 3235.0 3235.0 2 PMID:33223297;PMID:35124495 -3.2.1.133 * corallococcus sp. egb 972.17 972.17 1 PMID:34775631 -3.2.1.133 * lactiplantibacillus plantarum 78.2 36.4 3 * -3.2.1.133 * lactobacillus amylolyticus 265.3 90.65 10 * -3.2.1.133 * lactobacillus gasseri 58.7 58.7 1 PMID:16198511 -3.2.1.133 * parageobacillus galactosidasius 125.0 118.0 3 PMID:34829688 -3.2.1.133 * pyrococcus sp. 1.25 1.25 1 PMID:23884203 -3.2.1.133 * shouchella lehensis 2435.5 2435.5 1 * -3.2.1.133 * staphylothermus marinus 66.96 66.96 1 PMID:28887188 -3.2.1.133 * thermofilum pendens 785.5 535.1 15 PMID:19707756 -3.2.1.133 * thermus sp. 342.7 25.0 24 PMID:11714271;PMID:12902281;PMID:14763819 -3.2.1.135 * alkalihalophilus pseudofirmus 851.92 94.88 5 PMID:35805929 -3.2.1.135 * bacillus cereus 13.43 13.43 1 * -3.2.1.135 * lactiplantibacillus plantarum 5.96e-06 5.135e-06 2 PMID:19217549 -3.2.1.135 * ruminococcus bromii 72.5 72.5 1 PMID:30836186 -3.2.1.135 * uncultured microorganism 23.24 11.694999999999999 2 PMID:18540099 -3.2.1.136 * acetivibrio thermocellus 9.5 9.5 1 * -3.2.1.136 * dickeya chrysanthemi 46.0 0.15 3 PMID:26172579 -3.2.1.136 * evansstolkia leycettana 12.4 3.5 3 PMID:34361767 -3.2.1.136 * thermomyces lanuginosus 888.8 888.8 1 PMID:9648252 -3.2.1.137 * cellulomonas sp. 12.8 12.8 1 * -3.2.1.139 * aspergillus fumigatus 1.09 0.6900000000000001 2 PMID:23719223 -3.2.1.139 * aspergillus niger 61.0 61.0 1 * -3.2.1.139 * geobacillus stearothermophilus 42.0 28.65 2 PMID:11210113;PMID:11358519 -3.2.1.139 * paenibacillus sp. 16.3 4.35 4 PMID:27766358 -3.2.1.139 * phanerodontia chrysosporium 4.5 4.5 1 PMID:8590644 -3.2.1.139 * thermoanaerobacterium saccharolyticum 9.6 9.0 2 PMID:16534958;PMID:7496513 -3.2.1.139 * thermoascus aurantiacus 3.98 3.98 1 PMID:2802623 -3.2.1.139 * thermoclostridium stercorarium 1.647 1.647 1 PMID:7496513 -3.2.1.139 * uncultured bacterium 11.7 11.7 1 PMID:22526332 -3.2.1.14 * aeromonas hydrophila 27.0 13.538 2 * -3.2.1.14 * aeromonas media 10.37 10.37 1 PMID:35578780 -3.2.1.14 * alteromonas sp. 4.5 4.5 1 PMID:1464065 -3.2.1.14 * amylomyces rouxii 5.352 5.352 1 PMID:2778431 -3.2.1.14 * annona cherimola 3458.0 3458.0 1 PMID:20576315 -3.2.1.14 * aspergillus fumigatus 52.4 27.88 2 PMID:11454002;PMID:36005523 -3.2.1.14 * aspergillus sp. 8.0 4.55 2 PMID:17630125 -3.2.1.14 * autographa californica 5.7 5.7 1 PMID:20302895 -3.2.1.14 * autographa californica multiple nucleopolyhedrovirus 35.5 35.5 1 PMID:21897030 -3.2.1.14 * bacillus cereus 6.463 2.397 3 PMID:18843519;PMID:24342954 -3.2.1.14 * bacillus licheniformis 2.0 1.147 2 PMID:19190863;PMID:20133129 -3.2.1.14 * bacillus sp. (in: firmicutes) 312.0 3.7 7 PMID:12074700;PMID:12882563;PMID:7986376;PMID:9726888 -3.2.1.14 * bacillus subtilis 197.1 197.1 1 PMID:25112904 -3.2.1.14 * bambusa oldhamii 289.0 203.0 2 PMID:18998701 -3.2.1.14 * benincasa hispida 6688.0 6688.0 1 PMID:11330660 -3.2.1.14 * brevibacillus formosus 94.21 94.21 1 PMID:24473902 -3.2.1.14 * burkholderia cepacia 440000.0 440000.0 1 PMID:12469313 -3.2.1.14 * citrobacter freundii 140.6 140.6 1 PMID:24065288 -3.2.1.14 * citrus sinensis 0.2291 0.0193 7 PMID:8931350 -3.2.1.14 * clostridium paraputrificum 26.6 26.6 1 PMID:17091272 -3.2.1.14 * clostridium sp. e-16 17.7 17.549999999999997 2 PMID:16869903 -3.2.1.14 * coprinopsis cinerea 1252.0 3.1 8 PMID:30600059 -3.2.1.14 * cupiennius salei 1.725 1.725 1 PMID:7370275 -3.2.1.14 * dioscorea polystachya 6.23 6.23 1 PMID:25036674 -3.2.1.14 * drosera rotundifolia 92.2 85.41 5 PMID:32553964 -3.2.1.14 * ficus pumila var. awkeotsang 731.0 731.0 1 PMID:14634152 -3.2.1.14 * fusarium chlamydosporum 200.0 200.0 1 PMID:9783424 -3.2.1.14 * gallus gallus 756300.0 722150.0 2 * -3.2.1.14 * gemmabryum coronatum 196.85 138.925 2 PMID:33510258 -3.2.1.14 * gladiolus x gandavensis 159.7 147.39999999999998 2 PMID:9438997 -3.2.1.14 * glycine max 89.0 89.0 1 * -3.2.1.14 * halobacterium salinarum 0.513 0.513 1 PMID:23893326 -3.2.1.14 * hexagrammos otakii 3.04 1.25 3 PMID:16636466 -3.2.1.14 * homo sapiens 104.6 104.6 1 PMID:7836450 -3.2.1.14 * hordeum vulgare 139.0 72.655 2 PMID:19332152 -3.2.1.14 * lathyrus oleraceus 18.6 15.600000000000001 2 PMID:16666142 -3.2.1.14 * leucaena leucocephala 0.057 0.057 1 PMID:12784603 -3.2.1.14 * leucoagaricus gongylophorus 5800.0 5800.0 1 PMID:18848636 -3.2.1.14 * metarhizium anisopliae 146.0 2.18 12 PMID:14735222 -3.2.1.14 * microbispora sp. 4.6 4.6 1 PMID:12452952 -3.2.1.14 * monascus purpureus 1.02 0.935 2 PMID:11929279 -3.2.1.14 * moritella marina 0.91 0.16 3 PMID:18368288 -3.2.1.14 * neurospora crassa 0.77 0.77 1 PMID:2976112 -3.2.1.14 * niallia circulans 0.99 0.16 5 PMID:10441726 -3.2.1.14 * oryza sativa 2211.0 208.0 16 PMID:11911477;PMID:12834284;PMID:18211919;PMID:18323646 -3.2.1.14 * paenibacillus sp. 492.4 0.85 3 PMID:21049291;PMID:25036959;PMID:31957084 -3.2.1.14 * paenibacillus thermoaerophilus 1.32 1.32 1 PMID:25304023 -3.2.1.14 * paenibacillus timonensis 856375.0 125162.0 11 PMID:31349143 -3.2.1.14 * paenibacillus xylanexedens 16.0 5.4 3 PMID:34022308 -3.2.1.14 * paracoccidioides brasiliensis 13.6 10.5 2 PMID:16487309 -3.2.1.14 * penicillium ochrochloron 2360.0 2360.0 1 * -3.2.1.14 * penicillium oxalicum 162.1 162.1 1 PMID:34201595 -3.2.1.14 * penicillium sp. 12.3 12.3 1 PMID:19116167 -3.2.1.14 * pennahia argentata 3.33 3.33 1 PMID:19297695 -3.2.1.14 * petroselinum crispum 0.0047 0.0047 1 PMID:8477714 -3.2.1.14 * phaseolus lunatus 49.6 49.6 1 PMID:18782228 -3.2.1.14 * phaseolus vulgaris 144.0 106.0 2 PMID:19547968;PMID:24263941 -3.2.1.14 * phytolacca americana 1546.0 1333.0 2 PMID:7772831 -3.2.1.14 * picea abies 0.015 0.015 2 PMID:19629717 -3.2.1.14 * pochonia chlamydosporia 25.85 25.85 1 * -3.2.1.14 * priestia aryabhattai 175.4 146.0 3 PMID:35167419 -3.2.1.14 * pseudoalteromonas tunicata 2382.0 59.9 3 * -3.2.1.14 * pseudomonas sp. 0.175 0.0229 3 PMID:18378219;PMID:20622499 -3.2.1.14 * ralstonia sp. 52600.0 31600.0 3 PMID:23658014 -3.2.1.14 * rhizomucor miehei 18.1 1.6900000000000002 6 PMID:26709620;PMID:34358705 -3.2.1.14 * saccharomyces cerevisiae 1.4 1.4 1 PMID:6799506 -3.2.1.14 * scorpaena scrofa 6.51 6.51 1 PMID:22972353 -3.2.1.14 * serratia marcescens 19.0 0.7555000000000001 4 PMID:18323665;PMID:32097727;PMID:6762111 -3.2.1.14 * stenotrophomonas maltophilia 20.3 20.3 1 PMID:21945415 -3.2.1.14 * stomoxys calcitrans 0.7189 0.7189 1 PMID:7103511 -3.2.1.14 * streptomyces alfalfae 286.6 28.4 3 PMID:33259839 -3.2.1.14 * streptomyces antibioticus 0.444 0.444 1 * -3.2.1.14 * streptomyces chilikensis 60.53 60.53 1 PMID:30775271 -3.2.1.14 * streptomyces cyaneus 26.4 25.7 2 PMID:18175902;PMID:18603792 -3.2.1.14 * streptomyces griseus 255.0 1.295 10 PMID:10627034 -3.2.1.14 * streptomyces sampsonii 222.3 23.6 4 PMID:32170432 -3.2.1.14 * streptomyces sp. 426.3 4.96 6 PMID:11309080;PMID:12689517;PMID:5493208;PMID:7549109 -3.2.1.14 * streptomyces sp. da11 2.95 2.95 1 PMID:18626709 -3.2.1.14 * streptomyces thermoviolaceus 151.0 150.5 2 PMID:11570850 -3.2.1.14 * sulfurisphaera tokodaii 0.075 0.075 1 PMID:22154063 -3.2.1.14 * tenebrio molitor 11.9 11.9 1 PMID:17027845 -3.2.1.14 * thermoascus aurantiacus var. levisporus 26.2 4.0 3 PMID:20223653 -3.2.1.14 * thermochaetoides thermophila 6.1 1.9 3 PMID:20223653 -3.2.1.14 * thermococcus chitonophagus 310.0 1.26 9 PMID:12579379 -3.2.1.14 * thermomyces lanuginosus 88.64 88.64 1 PMID:35112660 -3.2.1.14 * trametes cinnabarina 6.22 6.22 1 * -3.2.1.14 * trichoderma gamsii 36.6 27.9 3 PMID:37367657 -3.2.1.14 * trichoderma harzianum 6.54 2.78 3 PMID:1606968 -3.2.1.14 * trichoderma viride 1.7 1.7 1 PMID:12483557 -3.2.1.14 * triticum aestivum 14.6 14.6 1 PMID:438221 -3.2.1.14 * vibrio proteolyticus 363.2 181.7 2 PMID:17690022;PMID:18214468 -3.2.1.14 * vibrio sp. 1.32 1.32 1 * -3.2.1.14 * vitis vinifera 5.36 5.36 1 PMID:19769368 -3.2.1.140 * bifidobacterium longum 37.2 37.2 1 PMID:23843461 -3.2.1.140 * streptomyces sp. 18.97 18.97 1 PMID:7689556 -3.2.1.141 * arthrobacter sp. 497.0 497.0 1 PMID:8611745 -3.2.1.141 * saccharolobus solfataricus 814.0 59.75 14 PMID:16968069;PMID:18563901 -3.2.1.141 * sulfolobus acidocaldarius 730.0 730.0 1 PMID:9063974 -3.2.1.142 * avena sativa 0.8 0.8 1 PMID:1170015 -3.2.1.142 * hordeum vulgare 14.2 14.2 1 PMID:19733243 -3.2.1.142 * lathyrus oleraceus 1.08 1.08 1 PMID:7190872;PMID:975121 -3.2.1.142 * oryza sativa 0.6 0.6 1 PMID:1170015 -3.2.1.142 * sorghum bicolor 1.08 1.08 1 PMID:7190872;PMID:975121 -3.2.1.142 * vicia faba 1.04 1.04 1 * -3.2.1.143 * bos taurus 85.0 69.95 3 PMID:3771556;PMID:4831224;PMID:8074279 -3.2.1.143 * cavia porcellus 32.5 22.95 2 PMID:2043631;PMID:3941108 -3.2.1.143 * homo sapiens 35.6 14.0 3 PMID:20684510;PMID:20884351;PMID:2379504 -3.2.1.143 * sus scrofa 32.1 22.950000000000003 2 PMID:6617643;PMID:8951044 -3.2.1.144 * crassostrea virginica 1433.0 1433.0 1 PMID:9334217 -3.2.1.145 * acetivibrio thermocellus 21.3 21.3 1 PMID:16672498 -3.2.1.145 * bifidobacterium longum 16.2 0.113 9 PMID:24837371 -3.2.1.145 * fusarium oxysporum 18.9 18.9 1 PMID:23429923 -3.2.1.145 * irpex lacteus 87.8 47.6 3 PMID:19717142;PMID:19809200;PMID:2158993 -3.2.1.145 * raphanus sativus 64.9 64.9 1 PMID:15980190 -3.2.1.145 * sphingomonas sp. 1.7 1.29 2 PMID:21452032 -3.2.1.145 * streptomyces sp. 40.0 40.0 2 PMID:22464224 -3.2.1.146 * aspergillus nidulans 94.4 87.45 2 PMID:33011078 -3.2.1.146 * aspergillus niger 26.3 13.265 2 PMID:11342249;PMID:36521309 -3.2.1.146 * penicillium charlesii 6.77 6.77 1 PMID:863879 -3.2.1.146 * penicillium fellutanum 25.0 25.0 1 PMID:11571168 -3.2.1.146 * trichoderma harzianum 1.0 1.0 1 PMID:1383191 -3.2.1.147 * arabidopsis thaliana 99.6 95.3 2 PMID:22682567 -3.2.1.147 * aspergillus niger 1.916 1.248 2 * -3.2.1.147 * aspergillus sydowii 111.0 10.07 3 * -3.2.1.147 * brassica juncea var. juncea 2.04 2.04 1 PMID:25977054 -3.2.1.147 * brassica napus 283.0 73.055 6 PMID:11858716 -3.2.1.147 * brassica nigra 1.24 1.24 1 PMID:25977054 -3.2.1.147 * brassica oleracea 14.46 1.615 14 PMID:25051514;PMID:25130502;PMID:25390544 -3.2.1.147 * brevicoryne brassicae 28.0 24.0 2 PMID:11102829;PMID:11179970 -3.2.1.147 * carica papaya 24.3 24.3 1 * -3.2.1.147 * citrobacter sp. wye1 47.31 32.95 6 PMID:35031980 -3.2.1.147 * crambe hispanica subsp. abyssinica 44.0 44.0 1 PMID:12696966 -3.2.1.147 * enterobacter cloacae 11.5 11.5 1 * -3.2.1.147 * lepidium latifolium 3.12 3.12 1 PMID:26527478 -3.2.1.147 * lepidium sativum 1.31 1.31 1 PMID:16666767 -3.2.1.147 * moringa oleifera 1.12 0.04 3 PMID:25130502 -3.2.1.147 * rahnella inusitata 12.73 6.99 3 PMID:35112855 -3.2.1.147 * raphanus sativus 164.0 0.909 4 PMID:25130502 -3.2.1.147 * shewanella baltica 6.951 3.8064999999999998 2 PMID:36232557 -3.2.1.147 * sinapis alba 60.0 0.48 5 PMID:25130502;PMID:25977054;PMID:5068825 -3.2.1.149 * aspergillus fumigatus 4.4 4.4 1 PMID:12036053 -3.2.1.149 * camellia sinensis 26.8 0.9 12 PMID:12481100;PMID:14579595;PMID:18256510 -3.2.1.149 * penicillium multicolor 1.5 1.5 1 PMID:16556987 -3.2.1.15 * achaetomium sp. xz-8 28120.0 28120.0 1 PMID:23871048 -3.2.1.15 * amylomyces rouxii 1328.0 672.05 2 * -3.2.1.15 * arabidopsis thaliana 2.713 0.679 3 PMID:19168715 -3.2.1.15 * aspergillus carbonarius 6120.0 3530.0 9 PMID:18357418 -3.2.1.15 * aspergillus foetidus 525.9 525.9 1 * -3.2.1.15 * aspergillus giganteus 7.35 4.81 5 PMID:18456950 -3.2.1.15 * aspergillus japonicus 1362.0 1362.0 1 * -3.2.1.15 * aspergillus luchuensis 4585.0 1506.0 3 PMID:16555006 -3.2.1.15 * aspergillus niger 246.0 78.1 6 PMID:1009121;PMID:23069766 -3.2.1.15 * aspergillus tubingensis 189.8 189.8 1 * -3.2.1.15 * bacillus paralicheniformis 2216.4 1158.48 2 PMID:29926218 -3.2.1.15 * bacillus subtilis 13790.0 13790.0 1 * -3.2.1.15 * borassus flabellifer 322.9 322.9 1 * -3.2.1.15 * botryosphaeria berengeriana 129.0 129.0 1 * -3.2.1.15 * botrytis cinerea 2049.0 1025.125 2 PMID:12398287;PMID:804319 -3.2.1.15 * burkholderia cepacia 21.1 12.350000000000001 2 PMID:17493828 -3.2.1.15 * burkholderia glumae 103.5 13.85 4 PMID:18631177 -3.2.1.15 * chondrostereum purpureum 560.0 418.0 9 PMID:16061394;PMID:19174189;PMID:26293910 -3.2.1.15 * fusarium oxysporum 148.0 148.0 1 PMID:1268232 -3.2.1.15 * fusarium verticillioides 178.6 98.63 2 PMID:11168425;PMID:15462530 -3.2.1.15 * kluyveromyces marxianus 219.0 219.0 1 PMID:11998843 -3.2.1.15 * malus domestica 0.102 0.06695 2 PMID:19453221 -3.2.1.15 * mucor ramosissimus 112600.0 56571.0 2 PMID:17123032 -3.2.1.15 * musa acuminata 7.53 7.53 1 * -3.2.1.15 * musca sp. 14.75 14.75 1 PMID:10872205 -3.2.1.15 * saccharomyces fragilis 145.0 134.3 3 * -3.2.1.15 * solanum lycopersicum 16.87 11.23 2 * -3.2.1.15 * tetracoccosporium sp. 6.17 6.17 1 PMID:17299207 -3.2.1.15 * thermoascus aurantiacus 5000.0 5000.0 1 PMID:17216535 -3.2.1.15 * trametes versicolor 248.0 162.6 4 PMID:18253772 -3.2.1.15 * trichoderma harzianum 276.0 148.5 2 PMID:16872705 -3.2.1.15 * uapaca kirkiana 0.00664 0.004315 2 * -3.2.1.15 * wickerhamomyces anomalus 258.0 258.0 1 * -3.2.1.150 * geotrichum sp. 15.31 15.0 3 PMID:12374797 -3.2.1.151 * aspergillus aculeatus 260.0 260.0 1 PMID:9884411 -3.2.1.151 * aspergillus cervinus 542.0 542.0 1 PMID:31332485 -3.2.1.151 * aspergillus fumigatus 11.9 11.9 1 PMID:28013403 -3.2.1.151 * aspergillus niger 113.0 19.0 5 PMID:11916668;PMID:18072936;PMID:19433323;PMID:23241981 -3.2.1.151 * geotrichum sp. m128 68.0 68.0 1 PMID:14987996 -3.2.1.151 * lathyrus oleraceus 1.294 1.294 1 PMID:12223734 -3.2.1.151 * penicillium canescens 21.0 21.0 1 PMID:20331423 -3.2.1.151 * penicillium oxalicum 172.0 172.0 1 PMID:26840178 -3.2.1.151 * talaromyces verruculosus 52.0 27.5 2 PMID:20331423 -3.2.1.151 * thermothelomyces heterothallicus 0.2 0.15000000000000002 2 PMID:23241981 -3.2.1.151 * thermothelomyces thermophilus 80.0 27.85 4 PMID:23241981;PMID:28477154 -3.2.1.151 * trichoderma reesei 1.6 1.175 2 PMID:23241981 -3.2.1.152 * arabidopsis thaliana 0.026 0.026 1 PMID:15247239 -3.2.1.152 * lilium longiflorum 0.004 0.004 1 PMID:9990135 -3.2.1.153 * cichorium intybus 0.0205 0.01635 2 PMID:19037899 -3.2.1.153 * triticum aestivum 14.6 13.399999999999999 2 PMID:12586886 -3.2.1.154 * actinomyces viscosus 851.2 851.2 1 PMID:3679542 -3.2.1.154 * beta vulgaris 12.5 12.5 1 PMID:14617070 -3.2.1.154 * lactiplantibacillus pentosus 260.9 260.9 1 PMID:12086179 -3.2.1.154 * streptococcus mutans 204.5 66.4 3 PMID:1522814;PMID:3308844 -3.2.1.157 * cellulophaga baltica 571.2 296.5 2 PMID:33157133 -3.2.1.157 * cellulophaga sp. 1870.0 1870.0 2 PMID:23690050 -3.2.1.157 * cellulophaga sp. qy3 365.9 365.9 1 * -3.2.1.157 * flavobacterium sp. ys-80-122 1207.8 1207.8 1 PMID:28435055 -3.2.1.157 * microbulbifer thermotolerans 124.55 80.6 4 PMID:20686828 -3.2.1.157 * uncultured bacterium 8068.0 8068.0 1 * -3.2.1.157 * wenyingzhuangia fucanilytica 11.55 11.55 1 PMID:28760444 -3.2.1.158 * alteromonas agarilytica 6423.0 6423.0 1 * -3.2.1.158 * catenovulum maritimum 206.1 206.1 1 * -3.2.1.158 * thalassomonas sp. 40.7 40.7 1 PMID:15902469 -3.2.1.159 * bacillus sp. (in: firmicutes) 22.2 22.2 1 PMID:16233232 -3.2.1.159 * vibrio sp. 92.0 92.0 1 PMID:7961439 -3.2.1.161 * dalbergia nigrescens 9.2 9.2 1 PMID:16098548 -3.2.1.161 * viburnum furcatum 42.2 21.235000000000003 2 PMID:14976214;PMID:18667453 -3.2.1.162 * bacillus sp. (in: firmicutes) 105.9 105.9 1 PMID:24737075 -3.2.1.162 * bacillus sp. lc50-1 105.9 105.9 1 * -3.2.1.162 * maribacter vaceletii 418.68 216.005 2 PMID:36112087 -3.2.1.163 * aspergillus phoenicis 48.0 48.0 1 PMID:15721331 -3.2.1.163 * homo sapiens 0.9 0.45245 2 PMID:19722277 -3.2.1.164 * aspergillus niger 25.29 25.29 1 * -3.2.1.164 * fusarium oxysporum 1.55 1.55 1 PMID:17351093 -3.2.1.164 * neurospora crassa 292.0 242.0 2 PMID:20932514 -3.2.1.164 * trichoderma viride 0.017 0.017 1 PMID:19717142 -3.2.1.165 * aspergillus flavus 1167.0 1167.0 1 * -3.2.1.165 * aspergillus fumigatus 13.0 9.19 3 PMID:16289917;PMID:28330083 -3.2.1.165 * aspergillus oryzae 38.8 38.8 1 PMID:11055393 -3.2.1.165 * penicillium sp. 39.66 39.66 1 * -3.2.1.165 * penicillium sp. ib-37-2a 5.643 2.8819999999999997 2 PMID:30656484 -3.2.1.165 * photobacterium profundum 0.046 0.0255 2 PMID:21098515 -3.2.1.165 * talaromyces funiculosus 41.2 41.2 1 * -3.2.1.165 * trichoderma reesei 27.3 27.3 1 PMID:16349528 -3.2.1.166 * burkholderia pseudomallei 8.0 8.0 1 PMID:31143933 -3.2.1.167 * levilactobacillus brevis 7.57 4.4270000000000005 2 PMID:20075633;PMID:24253830 -3.2.1.167 * scutellaria baicalensis 173.4 143.7 2 PMID:8593473 -3.2.1.167 * scutellaria viscidula 9.37 9.364999999999998 2 * -3.2.1.168 * actinoplanes missouriensis 1.8 1.8 1 PMID:26549237 -3.2.1.169 * homo sapiens 2.035 1.68 3 PMID:16584714 -3.2.1.17 * gallus gallus 40000.0 40000.0 1 * -3.2.1.17 * ictalurus punctatus 48330.0 48330.0 1 PMID:23978564 -3.2.1.17 * liolophura japonica 0.387 0.387 1 * -3.2.1.17 * meretrix lusoria 1227.0 923.5 2 PMID:24200802 -3.2.1.17 * monodonta labio 2.98 2.98 1 * -3.2.1.17 * omphalius pfeifferi 4.32 4.32 1 * -3.2.1.17 * pseudomonas aeruginosa 0.103 0.094 2 PMID:9023918 -3.2.1.17 * ruditapes philippinarum 37600.0 37600.0 1 * -3.2.1.17 * salmo salar 18800.0 15650.0 2 PMID:23396098 -3.2.1.17 * thermus virus in93 31050.0 31050.0 1 PMID:18831965 -3.2.1.171 * aspergillus aculeatus 2.5 1.45 2 PMID:26255130 -3.2.1.171 * aspergillus niger 0.9 0.9 1 PMID:26255130 -3.2.1.171 * irpex lacteus 75.0 51.9 2 PMID:22101785 -3.2.1.173 * aspergillus aculeatus 21.0 18.5 2 PMID:26255130 -3.2.1.174 * aspergillus aculeatus 57.6 35.25 2 PMID:26255130 -3.2.1.174 * penicillium chrysogenum 39.6 39.6 1 PMID:28110667 -3.2.1.175 * arabidopsis thaliana 0.017 0.017 1 PMID:17923167 -3.2.1.176 * acetivibrio thermocellus 340.0 7.5 3 PMID:11782517 -3.2.1.176 * geotrichum candidum 275000.0 2150.0 5 PMID:26367132 -3.2.1.176 * mycothermus thermophilus 11.7 11.7 1 PMID:23564627 -3.2.1.176 * paenibacillus sp. 0.00488 0.0033799999999999998 2 PMID:12823562 -3.2.1.176 * rasamsonia emersonii 24.8 0.56 9 PMID:12007616;PMID:23974371 -3.2.1.176 * talaromyces verruculosus 0.2 0.047 3 PMID:26301455 -3.2.1.177 * aspergillus oryzae 103.0 51.554 2 PMID:38239767 -3.2.1.177 * brassica oleracea var. capitata 1.7 1.7 1 PMID:11402218 -3.2.1.177 * escherichia coli 20.5 0.503 3 PMID:15294295;PMID:16631751 -3.2.1.177 * saccharolobus solfataricus 2.43 2.43 1 PMID:10801892 -3.2.1.177 * uncultured microorganism 69.5 0.54 5 PMID:27074950 -3.2.1.18 * actinomyces viscosus 680.0 680.0 1 PMID:2742753 -3.2.1.18 * arthrobacter sp. 110.0 110.0 1 PMID:629985 -3.2.1.18 * aspergillus fumigatus 0.0409 0.02051 2 PMID:20652740 -3.2.1.18 * asterias rubens 0.0014 0.0014 1 PMID:2713101 -3.2.1.18 * bacteroides fragilis 62.7 31.425 2 PMID:1333198 -3.2.1.18 * bacteroides thetaiotaomicron 100.9 49.55 6 PMID:23665536 -3.2.1.18 * bifidobacterium bifidum 0.00495 0.00495 1 PMID:30027820 -3.2.1.18 * bifidobacterium longum subsp. infantis 0.43 0.43 1 PMID:7216169 -3.2.1.18 * bos taurus 59.4 29.755 2 PMID:6816237 -3.2.1.18 * clostridium chauvoei 24.4 24.4 1 PMID:1823619 -3.2.1.18 * clostridium perfringens 740.0 390.0 7 PMID:171212;PMID:2885013;PMID:8561916 -3.2.1.18 * clostridium tertium 0.7 0.7 1 PMID:9832614 -3.2.1.18 * corynebacterium ulcerans 0.23 0.23 1 PMID:6796488 -3.2.1.18 * cricetulus griseus 10.1 5.5495 2 PMID:11270812;PMID:8286858 -3.2.1.18 * danio rerio 0.03985 0.013385999999999999 4 PMID:34022291 -3.2.1.18 * entamoeba histolytica 4.05 4.05 1 PMID:12632168 -3.2.1.18 * homo sapiens 0.04 0.0024 3 PMID:2713101;PMID:6735353 -3.2.1.18 * influenza a virus 11.58 2.13 3 PMID:12931027 -3.2.1.18 * macrobdella sp. 2860.0 2860.0 1 PMID:8034634 -3.2.1.18 * oryctolagus cuniculus 0.37 0.37 1 PMID:66917 -3.2.1.18 * paenarthrobacter ureafaciens 63.6 50.3 2 PMID:591509 -3.2.1.18 * pasteurella multocida 10.4 1.9 3 PMID:11092845;PMID:35676312 -3.2.1.18 * patiria pectinifera 17.2 17.2 1 PMID:11026668 -3.2.1.18 * rattus norvegicus 308.0 165.0 3 PMID:3997846;PMID:6723666 -3.2.1.18 * salmonella enterica subsp. enterica serovar typhimurium 3.9 3.9 1 PMID:1769974 -3.2.1.18 * streptococcus oralis 0.36 0.36 1 PMID:10707943 -3.2.1.18 * streptococcus pneumoniae 341.8 286.4 2 PMID:4190297;PMID:4402078 -3.2.1.18 * streptococcus sp. 1532.0 1532.0 1 PMID:4460881 -3.2.1.18 * sus scrofa 0.12 0.067 2 PMID:10739947;PMID:5706143 -3.2.1.18 * triatoma infestans 20.0 20.0 1 PMID:9733752 -3.2.1.18 * trypanosoma brucei 5.38 5.38 1 PMID:1518530 -3.2.1.18 * trypanosoma cruzi 0.001 0.001 1 PMID:3120189 -3.2.1.18 * trypanosoma evansi 174.0 174.0 1 PMID:12939050 -3.2.1.18 * trypanosoma vivax 31.02 31.009999999999998 2 PMID:15898128 -3.2.1.18 * unidentified influenza virus 378.0 346.0 2 PMID:19038288 -3.2.1.180 * bacillus sp. (in: firmicutes) 5.3 5.3 1 PMID:24403065 -3.2.1.180 * pedobacter heparinus 15.0 12.0 3 PMID:24403065 -3.2.1.180 * streptococcus agalactiae 17.0 17.0 1 PMID:24403065 -3.2.1.180 * streptococcus pneumoniae 6.1 6.1 1 PMID:24403065 -3.2.1.180 * streptococcus pyogenes 5.3 5.3 1 PMID:24403065 -3.2.1.181 * aspergillus flavus 1.0 1.0 1 PMID:29121496 -3.2.1.181 * flammulina velutipes 17.0 14.9 2 PMID:21653698;PMID:29121496 -3.2.1.181 * neurospora crassa 15.0 15.0 1 PMID:29121496 -3.2.1.185 * bifidobacterium longum 2.1 2.1 1 PMID:21914802 -3.2.1.186 * hellenia speciosa 325.0 325.0 1 PMID:8549824 -3.2.1.186 * solanum torvum 6.0 6.0 1 PMID:27055587 -3.2.1.188 * avena sativa 2.72 2.72 3 PMID:8000004;PMID:8013661 -3.2.1.189 * absidia sp. (in: mucoromycotan fungi) 1.94 1.94 1 PMID:20622501 -3.2.1.190 * sus scrofa 88.0 88.0 1 PMID:16079518 -3.2.1.191 * aspergillus sp. 6.54 3.277 2 * -3.2.1.191 * clavibacter michiganensis 2.189 1.11555 2 PMID:25820645 -3.2.1.191 * esteya vermicola 290.0 290.0 1 PMID:26383974 -3.2.1.191 * panax ginseng 2.0 2.0 1 PMID:26383974 -3.2.1.191 * sphingopyxis alaskensis 309.0 309.0 1 PMID:26383974 -3.2.1.191 * terrabacter ginsenosidimutans 76.0 76.0 1 PMID:26383974 -3.2.1.192 * aspergillus sp. 6.54 3.277 2 * -3.2.1.192 * gordonia terrae 250.0 133.2 2 PMID:25457989 -3.2.1.192 * pseudothermotoga thermarum 70.7 70.7 1 * -3.2.1.192 * thermotoga petrophila 95.7 95.7 1 PMID:25838236 -3.2.1.193 * armillaria mellea 17.9 17.9 1 PMID:27837549 -3.2.1.193 * aspergillus sp. 2.4 2.4 1 PMID:17268094 -3.2.1.193 * microbacterium esteraromaticum 29.0 29.0 1 PMID:26383974 -3.2.1.193 * paecilomyces variotii 137.0 137.0 1 PMID:26383974 -3.2.1.193 * saccharolobus solfataricus 2020.0 2020.0 1 PMID:26383974 -3.2.1.194 * absidia sp. (in: mucoromycotan fungi) 1.0 1.0 1 PMID:26383974 -3.2.1.194 * aspergillus niger 4.0 4.0 1 PMID:26383974 -3.2.1.194 * aspergillus sp. 2.0 1.7 3 PMID:22031031;PMID:26383974 -3.2.1.194 * fusarium subglutinans 136.0 136.0 1 PMID:26383974 -3.2.1.194 * gordonia terrae 132.0 11.5 5 PMID:25457989 -3.2.1.194 * penicillium sclerotiorum 136.0 136.0 1 PMID:26383974 -3.2.1.194 * pyrococcus furiosus 912.0 457.0 2 PMID:26383974 -3.2.1.194 * thermoanaerobacterium thermosaccharolyticum 4.5 4.5 1 PMID:26383974 -3.2.1.197 * dyadobacter fermentans 37.0 37.0 1 PMID:26476324 -3.2.1.2 * abrus precatorius 38.24 22.29 4 PMID:25863622 -3.2.1.2 * bacillus cereus 2182.0 2182.0 1 * -3.2.1.2 * camelus bactrianus 561.0 561.0 1 PMID:19291574 -3.2.1.2 * dioscorea batatus 161.0 161.0 1 * -3.2.1.2 * entamoeba invadens 65.1 65.1 1 PMID:9027750 -3.2.1.2 * glycine max 1187.0 1187.0 1 PMID:7763795 -3.2.1.2 * hordeum vulgare 222.0 222.0 1 PMID:4672101 -3.2.1.2 * ipomoea batatas 4664.0 4464.0 3 PMID:19021791 -3.2.1.2 * lathyrus oleraceus 1030.0 1030.0 1 PMID:16667324 -3.2.1.2 * medicago sativa 1077.0 1077.0 1 PMID:2470731 -3.2.1.2 * nakazawaea holstii 0.475 0.475 1 PMID:15362290 -3.2.1.2 * oryza sativa 300.0 300.0 1 * -3.2.1.2 * paenibacillus polymyxa 1500.0 1500.0 1 * -3.2.1.2 * panicum miliaceum 103.9 103.9 1 PMID:14561508 -3.2.1.2 * phaffia rhodozyma 0.0685 0.0685 1 PMID:12641711 -3.2.1.2 * solanum tuberosum 5.0 5.0 1 * -3.2.1.2 * sorghum sp. 45.95 45.95 1 * -3.2.1.2 * thermoanaerobacterium thermosulfurigenes 4215.0 2361.65 2 PMID:2461701 -3.2.1.2 * vicia faba 100.0 100.0 1 PMID:5068824 -3.2.1.2 * wickerhamomyces anomalus 0.45 0.45 1 PMID:15362290 -3.2.1.20 * [bacillus] caldovelox 71.4 71.4 1 * -3.2.1.20 * amylomyces rouxii 1.32 1.32 1 PMID:5010298 -3.2.1.20 * anopheles aquasalis 0.012 0.012 1 PMID:17449310 -3.2.1.20 * apis cerana indica 1.6 1.6 1 PMID:23419073 -3.2.1.20 * apis cerana japonica 13.0 13.0 3 PMID:17151473 -3.2.1.20 * apis mellifera 11.3 11.3 1 PMID:11515546 -3.2.1.20 * aplysia fasciata 38.4 38.4 1 PMID:16290308 -3.2.1.20 * aspergillus nidulans 9.6 9.6 1 PMID:11872475 -3.2.1.20 * aspergillus niger 57.8 1.9625 10 PMID:20369871;PMID:380468 -3.2.1.20 * aureobasidium pullulans 316.8 316.8 1 * -3.2.1.20 * bacillus sp. (in: firmicutes) 81.23 81.23 1 PMID:7764968 -3.2.1.20 * bacillus thermoamyloliquefaciens 64.7 64.7 1 PMID:10945254 -3.2.1.20 * beta vulgaris 0.85 0.85 1 * -3.2.1.20 * caldanaerobacter subterraneus subsp. tengcongensis mb4 3.26 1.09 7 PMID:20075617 -3.2.1.20 * camelus dromedarius 0.043 0.0335 2 * -3.2.1.20 * chilo suppressalis 9e-06 7.65e-06 2 PMID:19523603 -3.2.1.20 * dysdercus peruvianus 7640.0 7640.0 1 * -3.2.1.20 * entamoeba histolytica 2.36 1.18135 2 PMID:14574111;PMID:15013735 -3.2.1.20 * equus caballus 29.3 29.3 1 PMID:6767500 -3.2.1.20 * fagopyrum esculentum 97.0 97.0 1 * -3.2.1.20 * geobacillus stearothermophilus 6890.0 6890.0 1 PMID:17525102 -3.2.1.20 * homo sapiens 32.0 23.5 3 PMID:18328816;PMID:6804453;PMID:9285074 -3.2.1.20 * hordeum vulgare 25.6 13.2035 2 PMID:10648165;PMID:16343940 -3.2.1.20 * lactobacillus acidophilus 1451.0 1451.0 1 PMID:6419677 -3.2.1.20 * lentinula edodes 0.2 0.2 1 * -3.2.1.20 * malbranchea cinnamomea 3.95 3.95 1 * -3.2.1.20 * mortierella alliacea 42.9 17.200000000000003 10 PMID:12506981 -3.2.1.20 * mucor racemosus 22.5 22.5 1 * -3.2.1.20 * mus musculus 0.0307 0.0154 5 PMID:17524301 -3.2.1.20 * oryza sativa 47.13 47.13 1 * -3.2.1.20 * panicum miliaceum 76.0 76.0 1 PMID:15845403 -3.2.1.20 * parageobacillus thermoglucosidasius 164.0 164.0 1 PMID:8145 -3.2.1.20 * penicillium oxalicum 13.56 13.56 1 * -3.2.1.20 * phaffia rhodozyma 700.0 700.0 1 PMID:16491468 -3.2.1.20 * purpureocillium lilacinum 12.4 12.4 1 PMID:12619670 -3.2.1.20 * pyrobaculum arsenaticum 5.84 5.84 2 PMID:30263460 -3.2.1.20 * pyrococcus furiosus 1760.0 619.0 4 PMID:11210505 -3.2.1.20 * rattus norvegicus 65.0 42.0 5 PMID:2141837;PMID:29602;PMID:7027956;PMID:7030134 -3.2.1.20 * rhizobium sp. 5.72 5.72 1 PMID:10388682 -3.2.1.20 * saccharolobus solfataricus 120900.0 18.8 5 PMID:7814342 -3.2.1.20 * saccharomyces cerevisiae 132.0 100.0 3 PMID:15291818;PMID:22927369 -3.2.1.20 * saccharomyces logos 42.7 32.0 2 * -3.2.1.20 * saccharomyces pastorianus 131.3 131.3 1 PMID:365220 -3.2.1.20 * saccharomycopsis fibuligera 175.0 168.0 2 PMID:8948429 -3.2.1.20 * schizosaccharomyces pombe 2.0 2.0 1 * -3.2.1.20 * sulfurisphaera tokodaii 12.7 12.7 1 PMID:23314368 -3.2.1.20 * sus scrofa 35.5 24.8 3 * -3.2.1.20 * talaromyces purpureogenus 284.7 284.7 1 * -3.2.1.20 * thermoanaerobacter thermohydrosulfuricus 5.2 5.2 1 * -3.2.1.20 * thermoascus aurantiacus 404.0 404.0 1 PMID:20799086 -3.2.1.20 * thermochaetoides thermophila 33.33 33.33 1 * -3.2.1.20 * thermococcus sp. 80.0 80.0 1 PMID:8547344 -3.2.1.20 * thermus caldophilus 999.5 999.5 1 * -3.2.1.20 * trichomonas vaginalis 101.0 23.5 4 PMID:11001140 -3.2.1.20 * vitis vinifera 492.0 492.0 1 PMID:24408102 -3.2.1.20 * zea indurata 22.5 22.5 1 * -3.2.1.20 * zea mays 54.3 54.3 1 * -3.2.1.200 * aspergillus griseoaurantiacus 93.75 50.61 2 PMID:28939517 -3.2.1.200 * saccharophagus degradans 80000.0 42950.0 2 PMID:14973034 -3.2.1.201 * thermococcus kodakarensis 3160.0 1483.5 4 PMID:11468293 -3.2.1.202 * vibrio furnissii 325.0 325.0 1 PMID:8969204 -3.2.1.203 * alicyclobacillus acidocaldarius 192.0 164.5 2 PMID:26729722 -3.2.1.203 * bacillus velezensis 14.89 13.66 4 * -3.2.1.203 * escherichia coli 1718.0 1718.0 1 PMID:30689537 -3.2.1.205 * kribbella flavida 19.6 19.6 1 PMID:34665923 -3.2.1.206 * olea europaea 3500.0 1965.15 2 PMID:19689134 -3.2.1.207 * bombyx mori 4.53 4.53 1 PMID:23376632 -3.2.1.207 * bos taurus 0.096 0.096 1 PMID:3122729 -3.2.1.207 * rattus norvegicus 0.782 0.5295 4 PMID:18803404;PMID:1910575;PMID:3888264 -3.2.1.207 * spodoptera frugiperda 4.65 4.65 1 PMID:23376632 -3.2.1.207 * sporothrix schenckii 0.457 0.25525000000000003 2 PMID:21927828 -3.2.1.207 * sus scrofa 0.501 0.326 2 PMID:6373255;PMID:9348113 -3.2.1.209 * candida albicans 0.0946 0.00215 16 PMID:16487319;PMID:19047746 -3.2.1.209 * gallus gallus 4000.0 4000.0 1 PMID:8797103 -3.2.1.21 * [candida] sake 140.3 140.3 1 PMID:11732712 -3.2.1.21 * acetivibrio thermocellus 127.0 120.15 2 PMID:116657 -3.2.1.21 * agroathelia rolfsii 51.0 38.0 2 PMID:6786226 -3.2.1.21 * agrobacterium tumefaciens 248.0 226.0 2 PMID:28873987 -3.2.1.21 * alternaria alternata 14.3 14.3 1 * -3.2.1.21 * alternaria sp. 383.0 337.5 4 PMID:25784958 -3.2.1.21 * apis mellifera 5.66 4.575 2 PMID:12020842 -3.2.1.21 * arabidopsis thaliana 148.5 20.34 3 PMID:18774938;PMID:20028477 -3.2.1.21 * arthrinium sp. 672.0 534.5 4 PMID:25784958 -3.2.1.21 * aspergillus fumigatus 99.6 50.8 2 * -3.2.1.21 * aspergillus japonicus 169.0 59.5 14 PMID:19538132 -3.2.1.21 * aspergillus niger 184.1 52.8 7 PMID:10327588;PMID:11963890;PMID:9438354 -3.2.1.21 * aspergillus oryzae 350.0 89.65 4 PMID:16650812;PMID:9758774 -3.2.1.21 * aspergillus pulverulentus 308.0 308.0 1 * -3.2.1.21 * aspergillus sp. 185.0 136.5 4 PMID:25784958 -3.2.1.21 * aspergillus terreus 210.0 210.0 1 PMID:16346147 -3.2.1.21 * aspergillus versicolor 499.15 278.31 2 PMID:33636259 -3.2.1.21 * aureobasidium sp. 359.0 346.5 4 PMID:25784958 -3.2.1.21 * bacillus sp. zj1308 110.5 110.5 1 PMID:26077129 -3.2.1.21 * bacillus subtilis 47.9 47.9 1 PMID:29093750 -3.2.1.21 * bipolaris sp. 336.0 309.0 4 PMID:25784958 -3.2.1.21 * bombyx mori 665.0 665.0 1 PMID:15970451 -3.2.1.21 * caldicellulosiruptor saccharolyticus 560.0 6.449999999999999 14 PMID:19577189;PMID:3128175 -3.2.1.21 * camellia sinensis 2.57 2.57 1 PMID:15944750 -3.2.1.21 * carica papaya 3.37 3.37 1 * -3.2.1.21 * cellulomonas biazotea 133.0 133.0 1 PMID:11570858 -3.2.1.21 * cellulomonas fimi 0.21 0.21 1 * -3.2.1.21 * cellulomonas flavigena 2.27 2.27 1 PMID:17334847 -3.2.1.21 * cellulomonas gilvus 5.55 2.35 4 * -3.2.1.21 * cephalosporium sp. 717.0 355.5 4 PMID:25784958 -3.2.1.21 * cerrena unicolor 114.0 114.0 1 PMID:29418014 -3.2.1.21 * chilo suppressalis 5e-06 4.000000000000001e-06 2 PMID:19523603 -3.2.1.21 * chloridium sp. 122.0 55.5 4 PMID:25784958 -3.2.1.21 * citrus sinensis 1.13 1.13 1 PMID:11559154 -3.2.1.21 * cladosporium sp. 95.0 70.0 4 PMID:25784958 -3.2.1.21 * coprinopsis cinerea 268.0 175.0 5 PMID:27030727 -3.2.1.21 * cordyceps sp. 75.0 61.0 4 PMID:25784958 -3.2.1.21 * dalbergia cochinchinensis 13.8 13.8 1 PMID:16814564 -3.2.1.21 * daldinia eschscholtzii 77.86 77.86 1 PMID:17439636 -3.2.1.21 * dioscorea caucasica 1.85 0.9750000000000001 2 PMID:15003418 -3.2.1.21 * dothideomycetes sp. 488.0 367.5 4 PMID:25784958 -3.2.1.21 * epicoccum sp. 813.0 609.5 4 PMID:25784958 -3.2.1.21 * eubacterium sp. 24.7 24.7 1 PMID:8845799 -3.2.1.21 * evernia prunastri 21.0 21.0 1 PMID:3137029 -3.2.1.21 * exophiala sp. 79.0 49.0 4 PMID:25784958 -3.2.1.21 * flavobacterium sp. 65.4 65.4 1 PMID:235305 -3.2.1.21 * fomitopsis palustris 191.0 191.0 1 PMID:18337693 -3.2.1.21 * fusarium oxysporum 16.4 16.4 1 PMID:7925351 -3.2.1.21 * fusarium proliferatum 0.041 0.0205405 2 * -3.2.1.21 * fusarium sp. 100.0 23.5 8 PMID:25784958 -3.2.1.21 * fusobacterium sp. 1.52 1.52 1 PMID:11440132 -3.2.1.21 * galleria mellonella 24.36 12.39 2 PMID:24789069 -3.2.1.21 * glycine max 1340.0 1000.0 2 PMID:11730862;PMID:16891302 -3.2.1.21 * hanseniaspora vineae 67.0 67.0 1 * -3.2.1.21 * hevea brasiliensis 168.0 126.0 3 PMID:19409582 -3.2.1.21 * homo sapiens 49.7 4.65 14 PMID:11784319;PMID:16039637;PMID:17064932;PMID:17555766;PMID:3918500;PMID:6796580 -3.2.1.21 * kluyveromyces marxianus 64.4 36.13 2 PMID:3314909 -3.2.1.21 * komagataella pastoris 11.0 11.0 1 PMID:16417459 -3.2.1.21 * kuraishia molischiana 56.0 56.0 1 PMID:7670194 -3.2.1.21 * lamium galeobdolon 34.083 0.287 26 PMID:30336442 -3.2.1.21 * lenzites trabea 8500.0 8500.0 1 * -3.2.1.21 * levilactobacillus brevis 70.9 6.45 6 PMID:19702863 -3.2.1.21 * lissachatina fulica 162.8 162.8 1 * -3.2.1.21 * littorina kurila 2.4 2.4 1 PMID:18675406 -3.2.1.21 * microdochium sp. 189.0 132.0 4 PMID:25784958 -3.2.1.21 * millerozyma farinosa 38.63 38.63 1 PMID:8486554 -3.2.1.21 * minimidochium sp. tms-2011 45.0 31.5 4 PMID:25784958 -3.2.1.21 * monascus purpureus 84.3 84.3 1 PMID:18633294 -3.2.1.21 * mycothermus thermophilus 266.9 31.6 35 PMID:15522500;PMID:20221730;PMID:27271847 -3.2.1.21 * nakazawaea peltata 108.0 108.0 1 PMID:8795205 -3.2.1.21 * nakazawaea wickerhamii 180.0 95.05 2 PMID:3936420;PMID:8987723 -3.2.1.21 * neotermes koshunensis 156.7 156.7 1 * -3.2.1.21 * neurospora crassa 143.0 48.0 7 PMID:25784958;PMID:26596358 -3.2.1.21 * nigrospora sp. 51.0 21.0 4 PMID:25784958 -3.2.1.21 * orobanche minor 21.3 10.685 2 PMID:20208378 -3.2.1.21 * oryza sativa 3.73 3.73 1 PMID:20570296 -3.2.1.21 * paecilomyces sp. 170.5 129.4 3 PMID:18256474 -3.2.1.21 * paecilomyces sp. 'thermophila' 97.2 97.2 1 PMID:18092750 -3.2.1.21 * paenibacillus polymyxa 2417.0 2417.0 1 PMID:1569036 -3.2.1.21 * paenibacillus sp. 74.6 57.0 2 PMID:16205911 -3.2.1.21 * pectobacterium carotovorum 553.0 553.0 1 PMID:15564664 -3.2.1.21 * penicillium aurantiogriseum 0.41 0.285 2 PMID:10380623 -3.2.1.21 * penicillium decumbens 3.15 3.15 1 * -3.2.1.21 * penicillium occitanis (nom. inval.) 173.0 138.0 2 PMID:18401747 -3.2.1.21 * penicillium sp. 226.0 178.5 4 PMID:25784958 -3.2.1.21 * penicillium sp. lmi01 1345.0 1345.0 1 * -3.2.1.21 * phanerodontia chrysosporium 95.0 38.5 4 PMID:25784958 -3.2.1.21 * pholiota adiposa 2088.0 2088.0 1 * -3.2.1.21 * phoma sp. 454.0 312.0 8 PMID:25784958 -3.2.1.21 * phytophthora infestans 0.17 0.17 1 PMID:11909624 -3.2.1.21 * plumeria obtusa 7.38 7.38 1 PMID:16894479 -3.2.1.21 * podophyllum peltatum 75800.0 75800.0 1 PMID:12637023 -3.2.1.21 * prunus armeniaca 281.0 281.0 1 * -3.2.1.21 * prunus avium 27.49 27.49 1 PMID:11297776 -3.2.1.21 * pseudomonas sp. 1485.0 1485.0 1 PMID:15053533 -3.2.1.21 * putranjiva roxburghii 119.0 119.0 1 * -3.2.1.21 * pyricularia oryzae 0.04 0.04 1 PMID:29039 -3.2.1.21 * pyrococcus furiosus 1300.0 6.8 11 PMID:24053641;PMID:24078126 -3.2.1.21 * rasamsonia emersonii 482.8 482.8 1 PMID:15555940 -3.2.1.21 * rattus sp. 1917.0 1917.0 1 PMID:2304 -3.2.1.21 * rhizomucor miehei 19.1 19.1 1 PMID:25577102 -3.2.1.21 * rhodonia placenta 427.0 61.5 4 PMID:25784958 -3.2.1.21 * rhynchophorus palmarum 25.1 12.895000000000001 2 PMID:19611239 -3.2.1.21 * rosa x damascena 1.1 1.1 1 PMID:18175907 -3.2.1.21 * ruminococcus albus 13.0 13.0 1 PMID:3918007 -3.2.1.21 * saccharolobus shibatae 0.0039 0.0039 1 * -3.2.1.21 * saccharolobus solfataricus 179.0 93.25 2 PMID:21898127;PMID:24060745 -3.2.1.21 * schwanniomyces etchellsii 35.0 7.185 4 PMID:12818193;PMID:15549293;PMID:3139044;PMID:9185848 -3.2.1.21 * schwanniomyces vanrijiae 1278.0 1278.0 1 PMID:12590497 -3.2.1.21 * sclerotinia sclerotiorum 584.0 277.5 3 PMID:12818193;PMID:14566067;PMID:3139044 -3.2.1.21 * scytalidium lignicola 167.5 167.5 1 PMID:18548555 -3.2.1.21 * sporothrix sp. 327.0 203.5 4 PMID:25784958 -3.2.1.21 * sporotrichum pulverulentum 79.0 79.0 1 * -3.2.1.21 * talaromyces funiculosus 178.0 178.0 1 PMID:18553736 -3.2.1.21 * talaromyces verruculosus 102.0 54.0 13 PMID:19538132 -3.2.1.21 * termitomyces clypeatus 57.47 9.219999999999999 8 PMID:1900198;PMID:20031400;PMID:20382376 -3.2.1.21 * thermoascus aurantiacus 771.0 614.95 2 PMID:12630320 -3.2.1.21 * thermoclostridium stercorarium 31.6 31.6 1 * -3.2.1.21 * thermofilum pendens 7.6 7.6 1 PMID:23266119 -3.2.1.21 * thermomyces dupontii 1429.0 784.0 2 PMID:16446002;PMID:26649918 -3.2.1.21 * thermomyces lanuginosus 9.65 8.625 2 * -3.2.1.21 * thermophilic anaerobic bacterium 149.0 149.0 1 PMID:3117033 -3.2.1.21 * thermoplasma acidophilum 113.0 3.35 8 PMID:19458917 -3.2.1.21 * thermosphaera aggregans 140.9 66.95 6 PMID:12859194 -3.2.1.21 * thermothelomyces thermophilus 97.7 44.5 6 PMID:23638383 -3.2.1.21 * thermotoga maritima 5.55 2.35 4 * -3.2.1.21 * thermotoga petrophila 130000.0 11700.0 8 PMID:22714267;PMID:28444598 -3.2.1.21 * thermus sp. 259.9 59.6 5 * -3.2.1.21 * trichocladium griseum 266.9 266.9 1 * -3.2.1.21 * trichoderma koningii 92.9 70.35 2 * -3.2.1.21 * trichoderma reesei 88.0 32.5 20 PMID:1599951;PMID:19538132;PMID:25784958;PMID:3109900 -3.2.1.21 * trichoderma sp. 739.0 422.5 8 PMID:25784958 -3.2.1.21 * trichoderma viride 0.4 0.4 1 * -3.2.1.21 * triticum aestivum 311.9 245.9 6 PMID:10750901;PMID:16751439 -3.2.1.21 * uncultured bacterium 46.3 24.604999999999997 2 PMID:19584532 -3.2.1.21 * uncultured microorganism 36.2 25.7 5 PMID:27557720 -3.2.1.21 * unidentified microorganism 422.0 248.0 3 * -3.2.1.21 * vanilla planifolia 177.6 177.6 1 PMID:12720410 -3.2.1.21 * verruciconidia persicina 255.0 255.0 1 PMID:9291624 -3.2.1.21 * volvariella volvacea 96.0 96.0 1 PMID:16215851 -3.2.1.21 * wickerhamomyces anomalus 207.0 207.0 1 * -3.2.1.21 * zea mays 13.5 9.45 2 PMID:18282703;PMID:8068000 -3.2.1.215 * bifidobacterium longum subsp. longum 13.3 13.3 1 PMID:33674431 -3.2.1.216 * pyrobaculum arsenaticum 4.86 4.86 1 PMID:30263460 -3.2.1.22 * acinetobacter sp. 12.0 8.0 3 PMID:28324395 -3.2.1.22 * agroathelia rolfsii 12.3 12.3 1 * -3.2.1.22 * aspergillus flavipes 3179.0 3179.0 1 PMID:14624479 -3.2.1.22 * aspergillus niger 1080.0 11.52 5 PMID:14112 -3.2.1.22 * aspergillus tamarii 1642.0 1598.0 3 PMID:6331398;PMID:6331399 -3.2.1.22 * aspergillus terreus 67.3 36.8 3 PMID:17177558;PMID:18543114 -3.2.1.22 * bacillus sp. (in: firmicutes) 20.0 20.0 1 * -3.2.1.22 * bacteroides ovatus 129.0 0.3 9 PMID:2981815 -3.2.1.22 * bifidobacterium breve 215.0 215.0 1 * -3.2.1.22 * caldanaerobius polysaccharolyticus 247.1 247.1 1 PMID:12236697 -3.2.1.22 * carica papaya 53.26 14.46 3 PMID:16325871 -3.2.1.22 * castanea sativa 1.8 1.8 1 * -3.2.1.22 * citrullus lanatus 49.9 49.9 1 PMID:3007446 -3.2.1.22 * cocos nucifera 24.5 24.5 1 * -3.2.1.22 * coffea sp. 94.5 74.1 3 PMID:1662502;PMID:4449459;PMID:8619622 -3.2.1.22 * cucumis sativus 230.0 0.004167 14 PMID:16661511 -3.2.1.22 * cucurbita pepo 3.09 3.09 1 PMID:16662884 -3.2.1.22 * cyamopsis tetragonoloba 52.1 52.1 1 * -3.2.1.22 * debaryomyces hansenii 87.52 45.275 2 * -3.2.1.22 * diehliomyces microsporus 11275.0 5642.105 2 PMID:26184012 -3.2.1.22 * escherichia coli 27350.0 27350.0 1 * -3.2.1.22 * fusarium sp. 48.33 48.33 1 PMID:19288093 -3.2.1.22 * ganoderma lucidum 23.2 23.2 1 PMID:12913291 -3.2.1.22 * geobacillus stearothermophilus 400.0 253.5 4 PMID:6257360 -3.2.1.22 * glycine max 540.0 53.25 6 PMID:11524115;PMID:16662262;PMID:17177558;PMID:8828798 -3.2.1.22 * halalkalibacterium halodurans 15.4 15.4 1 PMID:18776668 -3.2.1.22 * hapsidospora chrysogena 210.6 210.6 1 * -3.2.1.22 * helianthus annuus 104.9 95.35 2 PMID:12882552 -3.2.1.22 * homo sapiens 4070000.0 12.08 10 PMID:11049747;PMID:11087687;PMID:226532;PMID:39940;PMID:4354031;PMID:4733088;PMID:6256390;PMID:661600 -3.2.1.22 * lens culinaris 45.0 45.0 1 * -3.2.1.22 * limosilactobacillus fermentum 4.37 4.3 3 PMID:17048069 -3.2.1.22 * lupinus angustifolius 1600.0 942.5 2 * -3.2.1.22 * medicago sativa 3530.0 81.54 3 * -3.2.1.22 * micrococcus sp. 5.8 5.8 1 * -3.2.1.22 * monascus pilosus 175.0 175.0 1 PMID:16347214 -3.2.1.22 * mus musculus 30.8 30.8 1 PMID:8104 -3.2.1.22 * oryza sativa 119.7 9.13 5 PMID:12423882;PMID:17284836 -3.2.1.22 * penicillium canescens 1255.0 177.0 6 PMID:18294137 -3.2.1.22 * penicillium chrysogenum sp. 23 30.0 15.23 2 * -3.2.1.22 * penicillium duponti 23.6 23.6 1 PMID:1268329 -3.2.1.22 * penicillium griseoroseum 55.0 28.51 2 PMID:17177558 -3.2.1.22 * phanerodontia chrysosporium 170.0 153.5 2 PMID:10085226 -3.2.1.22 * prunus dulcis 14.8 14.8 1 PMID:6032983 -3.2.1.22 * pseudoalteromonas sp. 231.0 115.555 2 PMID:19629597 -3.2.1.22 * rattus norvegicus 22.0 22.0 1 PMID:6020428 -3.2.1.22 * rhizomucor miehei 198.0 198.0 1 PMID:22349190 -3.2.1.22 * rhizopus sp. 74.6 37.9 2 * -3.2.1.22 * rhizopus sp. accc 30795 56.61 56.61 1 PMID:19996679 -3.2.1.22 * saccharolobus solfataricus 4.25 2.215 2 PMID:16547025 -3.2.1.22 * saccharum officinarum 30.6 30.6 1 PMID:6279579 -3.2.1.22 * solanum lycopersicum 82.0 42.15 2 * -3.2.1.22 * sphingomonas sp. 225.0 6.9 5 PMID:23124345 -3.2.1.22 * stachys affinis 29.1 29.1 1 * -3.2.1.22 * tachigali multijuga 83.6 83.6 1 PMID:18834998 -3.2.1.22 * talaromyces flavus 619.0 312.375 2 PMID:17049401 -3.2.1.22 * thermomyces lanuginosus 1813.0 266.6 3 PMID:11078955;PMID:17008008 -3.2.1.22 * thermothielavioides terrestris 85.8 85.8 1 PMID:22453806 -3.2.1.22 * thermotoga maritima 225.0 225.0 1 PMID:11210503 -3.2.1.22 * thermotoga neapolitana 224.0 154.5 2 PMID:11210503;PMID:8979350 -3.2.1.22 * thermus sp. t2 247.0 247.0 1 PMID:11282611 -3.2.1.22 * trametes cinnabarina 298.0 260.0 2 * -3.2.1.22 * trichoderma reesei 30.0 30.0 1 PMID:8390816 -3.2.1.22 * trifolium repens 4900.0 3700.0 4 PMID:15549;PMID:33663 -3.2.1.22 * umbelopsis vinacea 2000.0 68.7 3 PMID:10427697 -3.2.1.22 * vigna radiata 89150.0 89150.0 1 PMID:6325188 -3.2.1.22 * vonarxula javanica 68.3 68.3 1 * -3.2.1.22 * yersinia pestis 21.2 21.2 1 PMID:18685186 -3.2.1.23 * achatina achatina 10.2 10.2 1 PMID:9367180 -3.2.1.23 * alicyclobacillus acidocaldarius 592.0 352.5 2 PMID:18068682 -3.2.1.23 * arthrobacter psychrolactophilus 20.4 20.4 1 PMID:17459724 -3.2.1.23 * arthrobacter sp. 2.6 1.475 2 PMID:19771412 -3.2.1.23 * aspergillus carbonarius 11.16 8.35 2 PMID:18401743 -3.2.1.23 * aspergillus niger 82.4 51.3 6 PMID:116848;PMID:19806354;PMID:9549105 -3.2.1.23 * aspergillus oryzae 299.0 55.6 8 PMID:16865665;PMID:236999;PMID:30980597 -3.2.1.23 * averrhoa carambola 332.0 332.0 1 PMID:15652572 -3.2.1.23 * bifidobacterium longum 168.6 168.6 1 * -3.2.1.23 * caldariella acidophila 11.6 11.6 1 * -3.2.1.23 * caldicellulosiruptor saccharolyticus 212.0 116.85 2 PMID:19662397 -3.2.1.23 * canis lupus familiaris 3.32 3.32 1 PMID:8243059 -3.2.1.23 * cucumis sativus 0.27 0.14750000000000002 2 PMID:20728921 -3.2.1.23 * erythrina variegata 109.0 109.0 1 PMID:17761389 -3.2.1.23 * geobacillus stearothermophilus 125.2 3.5 4 PMID:18420605;PMID:19666723 -3.2.1.23 * haloferax volcanii 42.0 42.0 1 PMID:9048905 -3.2.1.23 * halorubrum lacusprofundi 110.8 110.8 1 PMID:23320757 -3.2.1.23 * hamamotoa singularis 56.0 56.0 1 PMID:14969418 -3.2.1.23 * homo sapiens 23.0 23.0 1 PMID:3109378 -3.2.1.23 * hymenaea courbaril 0.581 0.581 1 PMID:17137787 -3.2.1.23 * kluyveromyces lactis 1709.0 1709.0 1 PMID:16366715 -3.2.1.23 * kluyveromyces marxianus 790.6 395.574 6 PMID:17625262;PMID:18592410 -3.2.1.23 * lacticaseibacillus casei 8.67 8.67 1 PMID:37599861 -3.2.1.23 * lactiplantibacillus pentosus 97.0 97.0 1 PMID:20669255 -3.2.1.23 * lactiplantibacillus plantarum 0.96 0.96 1 * -3.2.1.23 * lathyrus oleraceus 77.33 38.707499999999996 2 PMID:19552429 -3.2.1.23 * limosilactobacillus reuteri 180.0 169.0 2 PMID:16819907 -3.2.1.23 * macrotyloma geocarpum 0.9 0.9 1 * -3.2.1.23 * neurospora crassa 33.25 33.25 1 PMID:237204 -3.2.1.23 * niallia circulans 5.13 5.13 1 PMID:9557875 -3.2.1.23 * oreochromis niloticus 168.6 168.6 1 * -3.2.1.23 * oryza sativa 65.1 0.058 5 PMID:12723614 -3.2.1.23 * paecilomyces variotii 1410.0 1410.0 1 * -3.2.1.23 * paenibacillus macerans 279.2 279.2 1 * -3.2.1.23 * papiliotrema laurentii 12.3 12.3 1 * -3.2.1.23 * penicillium chrysogenum 5.84 5.84 1 PMID:11162383 -3.2.1.23 * penicillium citrinum 98.1 98.1 1 * -3.2.1.23 * penicillium multicolor 145.0 145.0 1 * -3.2.1.23 * priestia megaterium 59.9 59.9 1 PMID:18682899 -3.2.1.23 * prunus persica 0.125 0.125 1 PMID:12661763 -3.2.1.23 * pseudoalteromonas haloplanktis 138.2 138.2 1 PMID:11282601 -3.2.1.23 * pyrococcus furiosus 130.0 70.1 2 PMID:24462527 -3.2.1.23 * raphanus sativus 5.62 5.62 1 PMID:16666809 -3.2.1.23 * rattus norvegicus 52.0 1.973 5 PMID:418065;PMID:8329173;PMID:9247702 -3.2.1.23 * rhizomucor sp. 200.0 200.0 1 PMID:10572953 -3.2.1.23 * saccharolobus solfataricus 116.4 16.0 3 PMID:1732221;PMID:2105216 -3.2.1.23 * saccharomyces fragilis 90.0 90.0 1 * -3.2.1.23 * sterigmatomyces elviae 20.2 20.2 1 PMID:8526517 -3.2.1.23 * streptococcus mitis 2969.0 1768.5 4 PMID:19633119 -3.2.1.23 * streptococcus thermophilus 466.0 465.0 2 PMID:20472057 -3.2.1.23 * tenebrio molitor 13.7 13.7 1 PMID:12535683 -3.2.1.23 * thermoanaerobacter sp. 99.0 99.0 1 * -3.2.1.23 * thermus aquaticus 5.733 5.733 1 * -3.2.1.23 * thermus sp. 62.83 55.715 2 PMID:18551631;PMID:9757561 -3.2.1.23 * trametes cinnabarina 28.0 28.0 1 * -3.2.1.23 * treponema phagedenis 1126.0 1126.0 1 * -3.2.1.23 * trichoderma reesei 31.25 25.79 2 PMID:16702608 -3.2.1.23 * uncultured microorganism 36.2 25.7 5 PMID:27557720 -3.2.1.23 * uncultured soil bacterium 243.0 134.2 2 PMID:20614217 -3.2.1.23 * vigna radiata 95.69 67.64 4 PMID:11393513 -3.2.1.23 * xanthomonas campestris 0.407 0.407 1 PMID:16345439 -3.2.1.24 * aspergillus flavus 87.7 87.7 1 * -3.2.1.24 * aspergillus niger 91.0 91.0 1 PMID:5012761 -3.2.1.24 * aspergillus oryzae 12.0 8.75 2 PMID:3700367 -3.2.1.24 * aspergillus sp. 0.36 0.36 1 PMID:7632718 -3.2.1.24 * canavalia ensiformis 45.0 10.225 6 PMID:1156387;PMID:5145;PMID:5905120 -3.2.1.24 * candida albicans 2200.0 0.09 5 PMID:10336985;PMID:15128678;PMID:8454197 -3.2.1.24 * citrullus lanatus 40.0 40.0 1 * -3.2.1.24 * gallus gallus 11.0 11.0 1 PMID:9498562 -3.2.1.24 * helianthus annuus 199.9 182.0 3 * -3.2.1.24 * homo sapiens 4.6 2.5 3 PMID:3954735;PMID:8910458 -3.2.1.24 * lupinus angustifolius 15.94 8.935 2 * -3.2.1.24 * macaca radiata 0.057 0.053500000000000006 2 PMID:3140784;PMID:6477510 -3.2.1.24 * medicago sativa 215.0 215.0 1 PMID:6772149 -3.2.1.24 * mus musculus 1.86 1.86 1 PMID:9305783 -3.2.1.24 * picrophilus oshimae 6.6 6.6 1 PMID:17015651 -3.2.1.24 * rattus sp. 153.0 18.395 6 PMID:1849817;PMID:26839;PMID:3196037;PMID:6465;PMID:8033914;PMID:863880 -3.2.1.24 * rhodococcus erythropolis 13890.0 13890.0 1 * -3.2.1.24 * saccharolobus solfataricus 14.4 14.4 1 PMID:20696204 -3.2.1.24 * saccharomyces cerevisiae 450.0 6.0 3 PMID:3281936;PMID:338603;PMID:350285 -3.2.1.24 * styela plicata 37.0 37.0 1 PMID:6671967 -3.2.1.24 * sus scrofa 48.5 21.1 3 PMID:10407159;PMID:4690228;PMID:5488778 -3.2.1.24 * thermotoga maritima 5.62 4.91 2 PMID:12801516;PMID:16511275 -3.2.1.24 * triticum aestivum 8.33 8.33 1 * -3.2.1.24 * trypanosoma cruzi 16.33 8.524999999999999 2 PMID:1472763;PMID:9858640 -3.2.1.25 * aspergillus niger 188.0 101.15 2 PMID:623772;PMID:845158 -3.2.1.25 * aspergillus sulphureus 208.0 208.0 1 PMID:18401744 -3.2.1.25 * capra hircus 186.5 93.7915 2 PMID:1556126;PMID:3355501 -3.2.1.25 * cutaneotrichosporon cutaneum 27.0 27.0 1 * -3.2.1.25 * gallus gallus 20.6 20.6 1 PMID:5021602 -3.2.1.25 * homo sapiens 17.6 1.772 3 PMID:2808324;PMID:8652632 -3.2.1.25 * hordeum vulgare 0.506 0.506 1 PMID:4429703 -3.2.1.25 * lissachatina fulica 4.37 4.37 1 PMID:5026310 -3.2.1.25 * phlebia radiata 3732.0 1881.35 2 PMID:17650684 -3.2.1.25 * polyporus sulfureus 4.2 4.2 1 PMID:6478 -3.2.1.25 * solanum lycopersicum 0.307 0.307 1 PMID:12012251 -3.2.1.25 * thermoascus aurantiacus 3.66 1.98 2 * -3.2.1.25 * thermothielavioides terrestris 52.8 33.45 4 * -3.2.1.25 * thermotoga maritima 37.2 37.2 1 * -3.2.1.25 * thermotoga neapolitana 34.0 34.0 1 PMID:11210502 -3.2.1.25 * tremella fuciformis 20.0 20.0 1 PMID:26672 -3.2.1.25 * trifolium repens 45.61 39.235 2 PMID:8921369 -3.2.1.26 * arabidopsis thaliana 100.0 100.0 1 PMID:8580769 -3.2.1.26 * arthrobacter globiformis 101.0 101.0 1 PMID:15127791 -3.2.1.26 * aspergillus luchuensis 771.2 771.2 1 PMID:37107499 -3.2.1.26 * aspergillus niger 3290.0 96.0 3 PMID:8358833 -3.2.1.26 * aspergillus ochraceus 160.4 42.5 3 PMID:11693382 -3.2.1.26 * aspergillus terreus 555.0 279.45 2 PMID:24307498 -3.2.1.26 * aureobasidium pullulans 2180.0 1111.2 2 PMID:17609167 -3.2.1.26 * azotobacter chroococcum 0.02 0.02 1 * -3.2.1.26 * bambusa oldhamii 1695.0 884.3 3 PMID:16608237;PMID:19010503 -3.2.1.26 * beta vulgaris 2.465 2.465 1 * -3.2.1.26 * bifidobacterium adolescentis 86.0 86.0 1 PMID:20380746 -3.2.1.26 * bifidobacterium longum subsp. infantis 580.0 580.0 1 PMID:12460425 -3.2.1.26 * cichorium intybus 0.143 0.078 2 PMID:19037899 -3.2.1.26 * clostridium perfringens 330.0 330.0 1 PMID:9145517 -3.2.1.26 * corynebacterium glutamicum 345.0 345.0 1 * -3.2.1.26 * cucumis sativus 0.225 0.0485 22 * -3.2.1.26 * cyberlindnera jadinii 2560.0 2028.5 2 PMID:11825607 -3.2.1.26 * fusarium oxysporum 455.0 243.5 4 * -3.2.1.26 * fusarium solani 245.6 146.76 2 PMID:16787006 -3.2.1.26 * glycine max 48.0 48.0 1 PMID:1575518 -3.2.1.26 * helianthus tuberosus 0.0269 0.014 7 PMID:18600345 -3.2.1.26 * hordeum vulgare 192.0 109.0 3 PMID:8310063 -3.2.1.26 * ipomoea batatas 553.0 311.5 2 PMID:15853418 -3.2.1.26 * lathyrus oleraceus 16.6 8.71 2 PMID:20590984 -3.2.1.26 * leptothrix cholodnii 64.9 64.9 1 PMID:37102957 -3.2.1.26 * lilium auratum 2970.0 2970.0 1 PMID:16663453 -3.2.1.26 * lilium longiflorum 466.1 253.6 3 * -3.2.1.26 * paecilomyces variotii 601.0 601.0 1 PMID:22806841 -3.2.1.26 * penicillium citreonigrum 1.0 1.0 1 PMID:36579491 -3.2.1.26 * phaffia rhodozyma 5200.0 710.0 4 PMID:19088319 -3.2.1.26 * phyllostachys edulis 28.8 27.4 2 * -3.2.1.26 * phytophthora megasperma 117.0 117.0 1 PMID:7396503 -3.2.1.26 * portulaca oleracea 158.2 158.2 1 * -3.2.1.26 * prunus persica 0.866 0.866 1 * -3.2.1.26 * pseudomonas fluorescens 850.0 850.0 1 * -3.2.1.26 * pyrus pyrifolia 140.4 140.4 1 PMID:12711132 -3.2.1.26 * rhodotorula glutinis 12.0 12.0 1 PMID:12423880 -3.2.1.26 * saccharomyces cerevisiae 4800.0 1945.0 14 PMID:11115390;PMID:115881;PMID:17899389;PMID:21147526;PMID:237205;PMID:4946709 -3.2.1.26 * schizosaccharomyces pombe 1590.0 1590.0 1 PMID:2187435 -3.2.1.26 * solanum lycopersicum 11.5 8.1 2 PMID:15125584 -3.2.1.26 * thermotoga maritima 2390.0 2390.0 1 PMID:9720201 -3.2.1.26 * thermotoga neapolitana 51800.0 51800.0 1 PMID:19125220 -3.2.1.26 * trametes sanguinea 3996.0 3996.0 1 PMID:7669814 -3.2.1.26 * triticum aestivum 1305.0 1305.0 1 PMID:16664223 -3.2.1.26 * woodfordia fruticosa 48.72 48.72 1 PMID:22905381 -3.2.1.26 * zymomonas mobilis 456.0 39.0 5 PMID:18712547 -3.2.1.28 * acyrthosiphon pisum 88.6 88.6 1 PMID:34845557 -3.2.1.28 * apis mellifera 427.0 53.4 3 PMID:1144;PMID:11826961 -3.2.1.28 * ascaris suum 0.531 0.531 1 PMID:12941639 -3.2.1.28 * bombyx mori 144.7 1.03 5 PMID:20870456 -3.2.1.28 * chironomus riparius 75.0 75.0 1 PMID:20542873 -3.2.1.28 * cicer arietinum 117.0 58.75 2 * -3.2.1.28 * corynascus sepedonium 679.0 679.0 1 PMID:31470095 -3.2.1.28 * cyberlindnera jadinii 0.405 0.20750000000000002 2 PMID:22484163 -3.2.1.28 * dictyostelium discoideum 2000.0 1052.0 2 PMID:6847202;PMID:9242988 -3.2.1.28 * drosophila melanogaster 18.49 18.49 1 PMID:6766684 -3.2.1.28 * escherichia coli 6.2 3.35 2 PMID:25179874 -3.2.1.28 * halorhodospira halochloris 0.303 0.303 1 * -3.2.1.28 * metarhizium anisopliae 120.0 110.65 4 PMID:16980715;PMID:17419071 -3.2.1.28 * microvirga sp. mc18 24.0 24.0 1 PMID:33592252 -3.2.1.28 * mycolicibacterium smegmatis 36.99 18.6085 2 PMID:17319935 -3.2.1.28 * mycothermus thermophilus 3700.0 2700.0 2 PMID:8980633 -3.2.1.28 * neurospora crassa 80.0 80.0 1 PMID:19073263 -3.2.1.28 * nilaparvata lugens 39.4 25.799999999999997 2 PMID:19615372 -3.2.1.28 * oryctolagus cuniculus 343.0 327.5 2 PMID:6466686 -3.2.1.28 * phaseolus vulgaris 175.7 175.7 1 PMID:15907687 -3.2.1.28 * rattus norvegicus 127.0 64.2 2 PMID:18444;PMID:240424 -3.2.1.28 * saccharomyces cerevisiae 99.0 71.5 2 PMID:3286651;PMID:782286 -3.2.1.28 * spodoptera frugiperda 168.0 168.0 1 PMID:15475303 -3.2.1.28 * sus scrofa 278.0 176.5 2 PMID:20542873;PMID:3592657 -3.2.1.28 * tenebrio molitor 16.67 8.448 2 PMID:23770497 -3.2.1.28 * thermochaetoides thermophila 120.0 120.0 1 * -3.2.1.28 * thermomyces lanuginosus 126.3 125.15 2 PMID:10564806;PMID:356886 -3.2.1.28 * trichocladium griseum 106.7 90.30000000000001 2 PMID:2223824 -3.2.1.28 * trichoderma reesei 50.4 50.4 1 PMID:31976 -3.2.1.3 * acremonium charticola 23.7 23.7 1 PMID:16350024 -3.2.1.3 * acremonium sp. 978.0 978.0 1 * -3.2.1.3 * agroathelia rolfsii 47.0 40.0 6 PMID:9802217 -3.2.1.3 * arachniotus sp. 690.0 690.0 1 PMID:14584926 -3.2.1.3 * arthrobotrys conoides 165.8 165.8 1 * -3.2.1.3 * aspergillus awamori 21000.0 200.0 5 PMID:11054460;PMID:12646689 -3.2.1.3 * aspergillus candidus 560.0 560.0 1 * -3.2.1.3 * aspergillus flavus 6619.0 3374.41 2 * -3.2.1.3 * aspergillus fumigatus 150.0 107.5 2 PMID:36154122 -3.2.1.3 * aspergillus japonicus 301.77 301.77 1 PMID:28412339 -3.2.1.3 * aspergillus neotritici 39.64 34.3 5 PMID:28951303 -3.2.1.3 * aspergillus niger 216.0 37.77 8 PMID:15063197;PMID:18271982;PMID:24293795;PMID:24837950 -3.2.1.3 * aspergillus niveus 600.0 600.0 1 PMID:19697071 -3.2.1.3 * aspergillus oryzae 96.1 96.1 1 PMID:32623532 -3.2.1.3 * aspergillus phoenicis 40.8 36.7 2 PMID:6796572 -3.2.1.3 * aspergillus wentii 361.0 361.0 1 PMID:33783000 -3.2.1.3 * aureobasidium pullulans 298.0 297.65 2 * -3.2.1.3 * bacillus sp. (in: firmicutes) 34.0 34.0 1 PMID:15672284 -3.2.1.3 * beta vulgaris 102.2 94.7 3 PMID:16666261 -3.2.1.3 * caldanaerobacter subterraneus subsp. tengcongensis 37.1 36.85 2 PMID:23852641 -3.2.1.3 * caldanaerobacter subterraneus subsp. tengcongensis mb4 175.0 127.5 2 PMID:20155355;PMID:6796044 -3.2.1.3 * camelus dromedarius 16.25 8.635 2 PMID:15621512 -3.2.1.3 * clostridium thermoamylolyticum 1.8 1.8 1 * -3.2.1.3 * corallococcus coralloides 180.0 180.0 1 PMID:26102340 -3.2.1.3 * curvularia lunata 19.73 11.135 2 PMID:17823796 -3.2.1.3 * endomycopsis fibuligera 38.0 38.0 1 * -3.2.1.3 * endophytic fungus ef6 758.0 758.0 1 PMID:21950121 -3.2.1.3 * evansstolkia leycettana 658.3 496.2 3 PMID:34656167 -3.2.1.3 * gymnascella citrina 839.1 426.18 2 * -3.2.1.3 * humicola sp. 406.9 208.67 2 * -3.2.1.3 * meretrix lusoria 46.8 46.8 1 * -3.2.1.3 * monascus purpureus 74.5 50.2 2 PMID:20708432 -3.2.1.3 * monascus sp. (in: ascomycete fungi) 51.4 51.4 1 * -3.2.1.3 * mycothermus thermophilus 43.8 26.599999999999998 2 PMID:24031228 -3.2.1.3 * myrothecium sp. 250.0 250.0 1 * -3.2.1.3 * paecilomyces variotii 465.0 465.0 1 PMID:17938981 -3.2.1.3 * paenibacillus amylolyticus 2300.5 2300.5 1 PMID:30681161 -3.2.1.3 * penaeus japonicus 223.1 223.1 1 PMID:20509216 -3.2.1.3 * penicillium oxalicum 457.5 24.7 7 PMID:27777618 -3.2.1.3 * picrophilus oshimae 28.5 15.75 2 PMID:12448707 -3.2.1.3 * pseudozyma tsukubaensis 5507.0 5507.0 1 PMID:3937490 -3.2.1.3 * rhizopus sp. 38.5 21.6 2 PMID:16218653;PMID:17216300 -3.2.1.3 * saccharolobus solfataricus 56.3 56.3 1 PMID:15240266 -3.2.1.3 * saccharomyces cerevisiae 9.665 5.3325 2 PMID:2493265;PMID:3124820 -3.2.1.3 * streptosporangium sp. 421.0 421.0 1 PMID:12056484 -3.2.1.3 * talaromyces verruculosus 4.8 4.15 4 PMID:25541341 -3.2.1.3 * thermoanaerobacter ethanolicus 75.3 75.3 1 PMID:35997915 -3.2.1.3 * thermoanaerobacterium thermosaccharolyticum 54.4 54.4 1 PMID:16348541 -3.2.1.3 * thermochaetoides thermophila 71.2 43.965 2 PMID:16107755;PMID:18045411 -3.2.1.3 * thermomucor indicae-seudaticae 134.0 134.0 1 PMID:12790660 -3.2.1.3 * thermomyces lanuginosus 80.0 80.0 1 PMID:20155355;PMID:6796044 -3.2.1.3 * thermoplasma acidophilum 4.21 3.605 2 PMID:12448707;PMID:18080814 -3.2.1.3 * thermothelomyces thermophilus 25.0 8.65 4 PMID:25541341 -3.2.1.3 * thermothielavioides terrestris 2.8 2.8 1 PMID:14665735 -3.2.1.3 * trichocladium griseum 145.0 145.0 1 PMID:16535057 -3.2.1.3 * tricholoma matsutake 13.2 13.2 1 PMID:30122147 -3.2.1.31 * arabidopsis thaliana 23.0 23.0 1 PMID:18667448 -3.2.1.31 * aspergillus niger 30.6 29.3 3 PMID:11423108;PMID:18377882 -3.2.1.31 * escherichia coli 17.78 17.78 1 PMID:8845801 -3.2.1.31 * faecalibacterium prausnitzii 0.73 0.73 1 PMID:31096909 -3.2.1.31 * homo sapiens 31.33 31.33 1 PMID:8053907 -3.2.1.31 * lachnospira eligens 0.02 0.02 1 PMID:31096909 -3.2.1.31 * lentinula edodes 0.000144 0.000144 1 PMID:18068838 -3.2.1.31 * levilactobacillus brevis 1284.0 1284.0 1 PMID:20075633 -3.2.1.31 * mediterraneibacter gnavus 0.08 0.08 1 PMID:16000722 -3.2.1.31 * mytilus galloprovincialis 80.0 80.0 1 PMID:19015888 -3.2.1.31 * neurospora crassa 29.3 29.3 1 PMID:18377882 -3.2.1.31 * oryctolagus cuniculus 0.127 0.127 1 PMID:2108135 -3.2.1.31 * protubera nipponica 100.0 100.0 1 PMID:6530397 -3.2.1.31 * rattus norvegicus 95.0 95.0 1 PMID:64358 -3.2.1.31 * roseburia hominis 0.09 0.09 1 PMID:31096909 -3.2.1.31 * roseburia intestinalis 0.17 0.17 1 PMID:31096909 -3.2.1.31 * streptococcus equi 270.0 160.0 3 PMID:17221200 -3.2.1.31 * streptococcus sp. 0.19 0.1635 2 * -3.2.1.32 * alcaligenes sp. 17.5 17.5 1 PMID:12501421 -3.2.1.32 * aspergillus terreus 15.2 9.3 5 * -3.2.1.32 * bacillus sp. (in: firmicutes) 35.0 35.0 1 * -3.2.1.32 * bacillus subtilis 253.0 225.5 4 PMID:11861085 -3.2.1.32 * synthetic construct 4.48 2.8600000000000003 2 PMID:34426240 -3.2.1.32 * vibrio sp. 13.6 9.9 3 PMID:10635569;PMID:15743273 -3.2.1.33 * bos taurus 3100.0 3100.0 1 PMID:11530024 -3.2.1.33 * oryctolagus cuniculus 11.0 6.5 17 PMID:11947484;PMID:1991122;PMID:269742;PMID:2968814;PMID:4577202;PMID:4633324;PMID:4691506;PMID:5082944;PMID:5086952;PMID:5436157;PMID:5686296;PMID:5805288;PMID:6232392;PMID:6447697;PMID:6458221;PMID:7154963;PMID:7766615 -3.2.1.33 * saccharomyces cerevisiae 9.4 5.455 6 PMID:10873545;PMID:11947484;PMID:1597178;PMID:4577202;PMID:4691506;PMID:5424210 -3.2.1.33 * squalus acanthias 3.0 3.0 1 PMID:13809 -3.2.1.33 * thermococcus gammatolerans 733.3 733.3 1 PMID:35627012 -3.2.1.35 * apis mellifera 4.77 0.2451195 4 PMID:18024155 -3.2.1.35 * bacillus halotolerans 26.37 26.37 1 PMID:33152358 -3.2.1.35 * bos grunniens 20.8 20.4 3 PMID:35853550 -3.2.1.35 * bos taurus 9800.0 9800.0 1 PMID:35853550 -3.2.1.35 * bothrops atrox 437.5 437.5 1 PMID:35853550 -3.2.1.35 * crotalus durissus terrificus 5066.0 5066.0 1 PMID:35853550 -3.2.1.35 * hippasa partita 0.03767 0.019755 2 PMID:17548101 -3.2.1.35 * hirudo sp. 1200000.0 1200000.0 1 PMID:35853550 -3.2.1.35 * homo sapiens 61.15 1.975 6 PMID:20558297 -3.2.1.35 * ovis aries 330659.0 285095.0 2 PMID:37611686 -3.2.1.35 * ovis aries aries 7.47 7.47 1 * -3.2.1.35 * palamneus gravimanus 6412.0 6412.0 1 PMID:16359718 -3.2.1.35 * rattus norvegicus 4.64 3.1799999999999997 4 PMID:37616240 -3.2.1.35 * synthetic construct 4.77 2.63 2 PMID:18024155 -3.2.1.36 * bacillus sp. (in: firmicutes) 102.1 53.48 2 PMID:24736576 -3.2.1.36 * erpobdella obscura 0.722 0.5235 2 PMID:10631807 -3.2.1.36 * erpobdella punctata 0.278 0.2415 2 PMID:10631807 -3.2.1.36 * glossiphonia complanata 0.058 0.043000000000000003 2 PMID:10631807 -3.2.1.36 * haemopis marmorata 0.038 0.0325 2 PMID:10631807 -3.2.1.36 * helobdella stagnalis 0.055 0.0435 2 PMID:10631807 -3.2.1.36 * hirudo medicinalis 5000.0 42.05 3 PMID:10631807 -3.2.1.36 * placobdella ornata 0.102 0.0655 2 PMID:10631807 -3.2.1.36 * placobdella picta 0.117 0.114 2 PMID:10631807 -3.2.1.36 * theromyzon sp. 0.09 0.09 1 PMID:10631807 -3.2.1.37 * agroathelia rolfsii 1.25 1.25 1 * -3.2.1.37 * aspergillus awamori 34.1 34.1 1 * -3.2.1.37 * aspergillus brasiliensis 25.67 18.375 2 PMID:17415665 -3.2.1.37 * aspergillus fumigatus 16.2 16.2 1 * -3.2.1.37 * aspergillus japonicus 42.6 3.9 7 PMID:17415665;PMID:19916911 -3.2.1.37 * aspergillus nidulans 107.1 85.0 2 * -3.2.1.37 * aspergillus niger 125.0 26.6 11 PMID:17415665;PMID:26166179;PMID:29174354;PMID:4709621;PMID:6434508 -3.2.1.37 * aspergillus versicolor 59.6 55.45 2 * -3.2.1.37 * aureobasidium pullulans 7.3 7.3 1 * -3.2.1.37 * bacillus pumilus 28.3 26.75 2 PMID:1765080 -3.2.1.37 * bacillus sp. hj14 2.37 1.2 2 PMID:31387037 -3.2.1.37 * bifidobacterium breve 221.48 3.32 5 PMID:12913270;PMID:22534302;PMID:36706530 -3.2.1.37 * bifidobacterium dentium 12.4 1.695 6 PMID:34949752 -3.2.1.37 * blastobotrys adeninivorans 27.1 23.7 5 PMID:1512706 -3.2.1.37 * caldicellulosiruptor saccharolyticus 0.72 0.72 1 * -3.2.1.37 * ceratocystis fimbriata 0.126 0.07 2 * -3.2.1.37 * cucumis sativus 21.3 21.3 1 * -3.2.1.37 * cyberlindnera jadinii 27.4 27.4 1 PMID:11330664 -3.2.1.37 * dictyoglomus thermophilum 27.12 8.56 3 PMID:33598452 -3.2.1.37 * fusarium proliferatum 53.0 53.0 1 PMID:12835054 -3.2.1.37 * geobacillus stearothermophilus 34.2 34.2 1 PMID:2123854 -3.2.1.37 * geobacillus thermodenitrificans 18.33 11.59 2 PMID:37487384 -3.2.1.37 * malbranchea pulchella var. sulfurea 13.7 12.1 2 * -3.2.1.37 * medicago sativa 8.4 8.4 1 PMID:17615411 -3.2.1.37 * mycothermus thermophilus 65.0 65.0 1 PMID:15160297 -3.2.1.37 * neocallimastix frontalis 4.3 4.3 1 PMID:2126511 -3.2.1.37 * neurospora crassa 0.26 0.26 1 PMID:18555300 -3.2.1.37 * paenibacillus curdlanolyticus 0.3 0.3 1 * -3.2.1.37 * paenibacillus woosongensis 659.9 503.6 2 PMID:21193828 -3.2.1.37 * paenibacillus xylaniclasticus 0.25 0.25 1 PMID:36312872 -3.2.1.37 * parageobacillus thermantarcticus 160.0 160.0 1 PMID:15142626 -3.2.1.37 * penicillium wortmanni 61.2 35.25 4 * -3.2.1.37 * phanerodontia chrysosporium 1797.0 911.0 2 PMID:23474097;PMID:25300189 -3.2.1.37 * phlebia radiata 4.76 4.76 1 PMID:11720306 -3.2.1.37 * pomacea canaliculata 0.95 0.95 1 PMID:9063971 -3.2.1.37 * rasamsonia emersonii 3390.0 24.2 4 PMID:16752410 -3.2.1.37 * ruminiclostridium cellulolyticum 15.1 15.1 1 PMID:7574661 -3.2.1.37 * saccharolobus solfataricus 3.63 3.63 1 PMID:17033733 -3.2.1.37 * saccharum officinarum 3.8 3.8 1 PMID:6819293 -3.2.1.37 * shouchella clausii 7.9 4.6000000000000005 2 PMID:35661527 -3.2.1.37 * streptomyces sp. 12.3 12.3 1 * -3.2.1.37 * talaromyces purpureogenus 89.5 89.5 1 PMID:20562284 -3.2.1.37 * termitomyces clypeatus 94.0 94.0 1 * -3.2.1.37 * thermoanaerobacter ethanolicus 1073.0 470.5 4 PMID:1522062 -3.2.1.37 * thermoanaerobacterium saccharolyticum 45.8 25.665 2 PMID:21131522 -3.2.1.37 * thermoascus aurantiacus 151.0 151.0 1 PMID:2508562 -3.2.1.37 * thermobifida fusca 8.0 8.0 1 * -3.2.1.37 * thermotoga maritima 275.0 50.0 3 PMID:15604789 -3.2.1.37 * thermotoga petrophila 343.53 229.8 5 PMID:30616097 -3.2.1.37 * trichocladium griseum 19.6 19.6 1 * -3.2.1.37 * trichoderma koningii 3.02 3.02 1 * -3.2.1.37 * trichoderma reesei 1304.0 15.1 6 PMID:16752410;PMID:19916911 -3.2.1.37 * trichoderma viride 28.2 10.8 3 * -3.2.1.37 * uncultured rumen bacterium 12.1 8.8 2 PMID:22020745 -3.2.1.38 * achatina balteata 63.0 63.0 1 PMID:7213761 -3.2.1.38 * asclepias curassavica 2853.0 2853.0 1 * -3.2.1.38 * aspergillus phoenicis 7.6 7.6 1 PMID:1524431 -3.2.1.38 * bifidobacterium breve clb 67.3 60.95 2 PMID:9063964 -3.2.1.38 * citrobacter sp. 0.002 0.002 1 PMID:15993389 -3.2.1.38 * dalbergia cochinchinensis 62.0 55.0 2 PMID:8830058 -3.2.1.38 * haloferax volcanii 42.0 42.0 1 PMID:9048905 -3.2.1.38 * lactuca sativa 430.0 430.0 1 PMID:3409886 -3.2.1.38 * turbo cornutus 2.47 2.47 1 PMID:4690235 -3.2.1.38 * uncultured microorganism 36.2 25.7 5 PMID:27557720 -3.2.1.39 * acetivibrio thermocellus 2680.0 1510.0 2 PMID:12686644 -3.2.1.39 * agaricus bisporus 66.4 66.4 1 PMID:9922471 -3.2.1.39 * agaricus brasiliensis 48.5 26.095 2 * -3.2.1.39 * alternaria tenuissima 2150.0 2150.0 1 * -3.2.1.39 * anadara broughtonii 90.01 80.43 4 PMID:31000023 -3.2.1.39 * apium graveolens 78.4 78.4 1 * -3.2.1.39 * aplysia kurodai 172.0 172.0 1 PMID:19883786 -3.2.1.39 * archangium sp. ac19 112.3 6.3100000000000005 6 PMID:34477943 -3.2.1.39 * aspergillus fumigatus 1.16 0.71 5 PMID:20619350 -3.2.1.39 * aspergillus nidulans 1531.3 69.3 15 PMID:20602653;PMID:34246678 -3.2.1.39 * aspergillus versicolor 1750.0 1750.0 1 * -3.2.1.39 * azumapecten farreri 1.67 1.67 1 PMID:32947865 -3.2.1.39 * bacillus amyloliquefaciens 53.0 53.0 1 PMID:23108702 -3.2.1.39 * bacillus sp. (in: firmicutes) 369.6 192.3 2 * -3.2.1.39 * bacteroides difficilis 12.6 12.6 1 PMID:37376774 -3.2.1.39 * boscia senegalensis 549.0 549.0 1 PMID:11563825 -3.2.1.39 * cellulosimicrobium cellulans 49.1 8.235 4 PMID:11676595;PMID:16946451;PMID:21979581 -3.2.1.39 * cellulosimicrobium funkei 26.0 17.9 2 PMID:34439747 -3.2.1.39 * coprinopsis cinerea 3757.0 3094.0 5 PMID:26199012 -3.2.1.39 * cryptomeria japonica 6.26 6.26 2 PMID:31731097 -3.2.1.39 * euglena gracilis 0.5 0.5 1 PMID:36586565 -3.2.1.39 * flavobacterium dormitator 10.1 10.1 1 * -3.2.1.39 * flavobacterium sp. 0.33 0.33 1 PMID:4776863 -3.2.1.39 * formosa algae 24.0 24.0 1 PMID:28120311 -3.2.1.39 * gecarcoidea natalis 7.8 0.5985 4 PMID:18587122 -3.2.1.39 * glycine max 2.6 2.6 1 PMID:16662849 -3.2.1.39 * haliotis discus hannai 68.0 68.0 1 PMID:19446649 -3.2.1.39 * haliotis tuberculata 86.7 86.7 1 PMID:9821264 -3.2.1.39 * hevea brasiliensis 0.013 0.0115 2 * -3.2.1.39 * hordeum vulgare 281.5 230.25 4 PMID:12023973;PMID:8424790 -3.2.1.39 * lentinula edodes 1.85 1.85 1 PMID:21965406 -3.2.1.39 * littorina kurila 0.285 0.285 1 PMID:18675406 -3.2.1.39 * malus domestica 0.048 0.045 2 PMID:12765782 -3.2.1.39 * mizuhopecten yessoensis 6.0 3.0475 2 * -3.2.1.39 * musa x paradisiaca 0.0025 0.0025 1 PMID:19697038 -3.2.1.39 * niallia circulans 4.1 4.1 1 PMID:4310 -3.2.1.39 * nicotiana tabacum 67.33 67.33 1 * -3.2.1.39 * oryza sativa 500.0 0.85 6 PMID:34403886;PMID:9076936 -3.2.1.39 * paenibacillus sp. 286.0 286.0 1 PMID:12764561 -3.2.1.39 * paenibacillus sp. gkg 125.0 37.75 16 PMID:36296206 -3.2.1.39 * penicillium italicum 10.5 10.5 1 * -3.2.1.39 * porodisculus pendulus 70.8 70.8 1 * -3.2.1.39 * prunus avium 0.18 0.147 2 PMID:12765782 -3.2.1.39 * pyricularia oryzae 8.18 5.17 2 PMID:34378924 -3.2.1.39 * pyrococcus furiosus 1087.0 155.9 6 PMID:19154353 -3.2.1.39 * rhizoctonia solani 217.0 75.0 4 PMID:19022284 -3.2.1.39 * rhizomucor miehei 2.45 1.2825000000000002 2 PMID:26490553 -3.2.1.39 * rhizopus microsporus var. chinensis 4800.0 4800.0 1 * -3.2.1.39 * saccharomyces cerevisiae 9.62 1.165 6 PMID:17899389;PMID:6358190;PMID:8458852 -3.2.1.39 * schizophyllum commune 139.4 139.4 1 * -3.2.1.39 * schizosaccharomyces pombe 5.89 3.8899999999999997 2 PMID:7275933 -3.2.1.39 * sclerotium glucanicum 69.0 69.0 1 PMID:1627595 -3.2.1.39 * shouchella lehensis 376.73 233.01 3 PMID:32912685 -3.2.1.39 * shouchella lehensis g1 376.0 233.0 3 PMID:32912685 -3.2.1.39 * solanum tuberosum 484.0 90.0 5 PMID:19081847;PMID:25800964 -3.2.1.39 * spodoptera frugiperda 4480.0 4480.0 1 PMID:20816775 -3.2.1.39 * stachybotrys elegans 22.0 22.0 1 PMID:9933916 -3.2.1.39 * streptomyces sp. 236.0 118.11 2 PMID:19697016 -3.2.1.39 * tenebrio molitor 4.4 4.4 1 PMID:19840850 -3.2.1.39 * thermotoga petrophila 48.1 41.55 3 PMID:21352806 -3.2.1.39 * trichoderma harzianum 711.0 86.1 3 PMID:32279083;PMID:7592488 -3.2.1.39 * trichoderma koningii 409.5 206.7 2 PMID:16450064 -3.2.1.39 * yarrowia lipolytica 3349.0 1876.0 2 PMID:16921554 -3.2.1.4 * acetivibrio thermocellus 428.0 315.0 3 * -3.2.1.4 * alternaria sp. 186.0 91.0 4 PMID:25784958 -3.2.1.4 * arthrinium sp. 208.0 80.5 8 PMID:25784958 -3.2.1.4 * aspergillus fischeri 2020.0 2020.0 1 PMID:26360701 -3.2.1.4 * aspergillus glaucus 297.15 297.15 1 PMID:29681022 -3.2.1.4 * aspergillus niger 484.3 80.15 6 PMID:23241981;PMID:25331339;PMID:33319112 -3.2.1.4 * aspergillus oryzae 92.5 78.33500000000001 2 PMID:18704277 -3.2.1.4 * aspergillus sp. 24.0 20.5 4 PMID:25784958 -3.2.1.4 * aspergillus terreus 256.0 68.4 4 PMID:28088615 -3.2.1.4 * aspergillus tubingensis 97.95 97.95 1 PMID:29223094 -3.2.1.4 * aspergillus versicolor 0.048 0.048 1 * -3.2.1.4 * aspergillus wentii 0.05 0.05 1 * -3.2.1.4 * aureobasidium sp. 251.0 99.5 4 PMID:25784958 -3.2.1.4 * bacillus amyloliquefaciens 82.0 56.1 4 PMID:17320379;PMID:22561853;PMID:24398300 -3.2.1.4 * bacillus sp. (in: firmicutes) 450.0 64.95 4 PMID:15834791;PMID:18473955;PMID:22012583 -3.2.1.4 * bacillus sp. sr22 43.02 43.02 1 PMID:29926709 -3.2.1.4 * bacillus subtilis 66.4 7.66 9 PMID:19050861;PMID:22610115;PMID:34409950;PMID:7710279 -3.2.1.4 * bacillus vallismortis 123600.0 123600.0 1 PMID:25886936 -3.2.1.4 * bacterium enrichment culture 174.0 174.0 1 PMID:26052323 -3.2.1.4 * batocera horsfieldi 928.0 928.0 1 PMID:23201420 -3.2.1.4 * bellamya chinensis laeta 8.8 8.8 1 PMID:26921188 -3.2.1.4 * bipolaris sp. 44.0 22.5 4 PMID:25784958 -3.2.1.4 * bispora sp. mey-1 4040.0 3390.0 2 PMID:19590866 -3.2.1.4 * botryotinia ricini 57.92 57.92 1 PMID:30223157 -3.2.1.4 * caecomyces sp. cr4 59.1 35.7 2 PMID:18791765 -3.2.1.4 * cellulomonas flavigena 245.0 245.0 1 PMID:17985078 -3.2.1.4 * cephalosporium sp. 159.0 145.0 4 PMID:25784958 -3.2.1.4 * cherax destructor 19.09 9.52 6 PMID:18587122 -3.2.1.4 * chloridium sp. 46.0 11.0 4 PMID:25784958 -3.2.1.4 * citrobacter farmeri 8.7 8.7 1 PMID:27843715 -3.2.1.4 * cladosporium sp. 15.0 15.0 1 PMID:25784958 -3.2.1.4 * clostridium cellulovorans 0.33 0.29000000000000004 2 PMID:26808019 -3.2.1.4 * cohnella sp. a01 13.6 13.6 1 PMID:35717508 -3.2.1.4 * cordyceps sp. 65.0 34.5 4 PMID:25784958 -3.2.1.4 * cryptococcus sp. s-2 248.7 4.93 3 PMID:18479937 -3.2.1.4 * cryptopygus antarcticus 35.8 20.5 3 PMID:28156112 -3.2.1.4 * dolabella auricularia 277.5 277.5 1 PMID:6526811 -3.2.1.4 * dothideomycetes sp. 229.0 130.5 4 PMID:25784958 -3.2.1.4 * epicoccum sp. 280.0 235.5 4 PMID:25784958 -3.2.1.4 * euphausia pacifica 42.3 42.3 1 PMID:22981467 -3.2.1.4 * exophiala sp. 159.0 80.0 5 PMID:25784958 -3.2.1.4 * fibrobacter succinogenes 16.5 16.5 1 PMID:8864216 -3.2.1.4 * fomitopsis palustris 87.0 64.0 5 PMID:29789883 -3.2.1.4 * ganoderma lucidum 787.0 787.0 1 PMID:25895101 -3.2.1.4 * gecarcoidea natalis 12.74 6.453 4 PMID:18587122 -3.2.1.4 * gloeophyllum trabeum 200.6 31.5 6 PMID:30396396 -3.2.1.4 * gracilibacillus sp. 510.8 315.2 7 * -3.2.1.4 * gymnascella citrina 115.0 115.0 1 PMID:18228067 -3.2.1.4 * haloarcula sp. 71.2 71.2 1 PMID:23999019 -3.2.1.4 * irpex lacteus 13.06 13.06 1 PMID:7400113 -3.2.1.4 * lyrodus pedicellatus 5.3 5.3 1 * -3.2.1.4 * lysobacter enzymogenes 41.4 41.4 1 * -3.2.1.4 * marinobacter sp. 2549.0 2549.0 1 PMID:19711200 -3.2.1.4 * melanocarpus albomyces 980.0 450.0 3 * -3.2.1.4 * microdochium sp. 80.0 27.5 4 PMID:25784958 -3.2.1.4 * minimidochium sp. tms-2011 18.0 9.5 2 PMID:25784958 -3.2.1.4 * mucor circinelloides 43.0 43.0 1 * -3.2.1.4 * mycothermus thermophilus 372.0 45.25 10 PMID:23564627;PMID:25909505;PMID:29150773 -3.2.1.4 * neurospora crassa 48.0 1.05 9 PMID:25711741;PMID:25784958 -3.2.1.4 * niallia circulans 17.7 17.7 1 PMID:12020807 -3.2.1.4 * nigrospora sp. 83.0 32.0 4 PMID:25784958 -3.2.1.4 * novosphingobium sp. 31.4 31.4 1 PMID:35124880 -3.2.1.4 * paenibacillus barcinonensis 105.8 61.339999999999996 2 PMID:23124341 -3.2.1.4 * paenibacillus sp. m33 0.19 0.14 3 PMID:27862076 -3.2.1.4 * paenibacillus sp. y2 6.52 6.52 1 * -3.2.1.4 * penicillium sp. 57.0 51.5 4 PMID:25784958 -3.2.1.4 * phanerodontia chrysosporium 1444.0 32.0 7 PMID:25784958;PMID:26173955 -3.2.1.4 * phoma sp. 130.0 47.0 8 PMID:25784958 -3.2.1.4 * photobacterium panuliri 6.4 6.4 1 PMID:26494136 -3.2.1.4 * pomacea maculata 26.8 26.8 1 PMID:28711732 -3.2.1.4 * psacothea hilaris 150.0 150.0 1 PMID:12899703 -3.2.1.4 * rasamsonia emersonii 4254.0 2018.5 6 PMID:24668246 -3.2.1.4 * reticulitermes speratus 83.4 83.4 1 PMID:9134711 -3.2.1.4 * rhizobium leguminosarum bv. trifolii 152.0 152.0 1 PMID:18458328 -3.2.1.4 * rhodonia placenta 14.0 14.0 1 PMID:25784958 -3.2.1.4 * robillarda sp. 72.3 72.3 1 * -3.2.1.4 * saccharolobus shibatae 428.0 428.0 1 PMID:30225584 -3.2.1.4 * saccharolobus solfataricus 28.1 3.45 10 PMID:15456402;PMID:18568289;PMID:23627611 -3.2.1.4 * salinivibrio sp. ntu-05 32.4 32.4 1 * -3.2.1.4 * sclerotinia sclerotiorum 19.0 19.0 1 PMID:28811204 -3.2.1.4 * sporothrix sp. 384.0 176.0 3 PMID:25784958 -3.2.1.4 * sporotrichum pulverulentum 0.049 0.049 1 * -3.2.1.4 * streptomyces rochei 64.8 64.8 1 PMID:8659894 -3.2.1.4 * streptomyces ruber 4240.0 2543.4 2 * -3.2.1.4 * talaromyces pinophilus 19.73 17.695 4 PMID:22112826 -3.2.1.4 * talaromyces verruculosus 94.0 60.0 7 PMID:25869365;PMID:27440076;PMID:30935060 -3.2.1.4 * teleogryllus emma 1.254 0.673 5 PMID:18514003 -3.2.1.4 * thermoascus aurantiacus 88.0 66.45 2 PMID:25424281;PMID:28626700 -3.2.1.4 * thermobifida fusca 0.56 0.29 3 PMID:18402467;PMID:19697023 -3.2.1.4 * thermochaetoides thermophila 38.7 2.14 7 PMID:28528790;PMID:29440674;PMID:29842954 -3.2.1.4 * thermosipho sp. ld-2008 120.0 120.0 1 * -3.2.1.4 * thermothelomyces heterothallicus 9.2 0.135 4 PMID:23241981 -3.2.1.4 * thermothelomyces thermophilus 202.6 7.9 8 PMID:23241981;PMID:30396396 -3.2.1.4 * thermothielavioides terrestris 2500.0 2500.0 1 * -3.2.1.4 * thermotoga maritima 139.6 53.0 5 PMID:23627611;PMID:24398300;PMID:24910337 -3.2.1.4 * trametes hirsuta 45.0 45.0 1 PMID:17928699 -3.2.1.4 * trichoderma atroviride 119.9 119.9 1 PMID:28155168 -3.2.1.4 * trichoderma longibrachiatum 331.9 166.35 4 PMID:24398300;PMID:24910337 -3.2.1.4 * trichoderma reesei 213.1 17.0 5 PMID:17942322;PMID:23241981;PMID:25784958 -3.2.1.4 * trichoderma sp. 234.0 34.5 8 PMID:25784958 -3.2.1.4 * trichoderma viride 0.258 0.258 1 * -3.2.1.4 * uncultured archaeon 210.7 209.9 3 PMID:30547216 -3.2.1.4 * uncultured bacterium 692.0 65.53 13 PMID:25545469;PMID:26191525;PMID:29964118;PMID:30123929 -3.2.1.4 * uncultured rumen bacterium 220.0 220.0 1 * -3.2.1.4 * xanthomonas sp. ec102 1970.0 1970.0 1 PMID:24399319 -3.2.1.40 * absidia sp. (in: mucoromycotan fungi) 2.44 2.44 1 * -3.2.1.40 * acrostalagmus luteoalbus 526.0 526.0 1 PMID:21221705 -3.2.1.40 * alternaria alternata 21.7 21.7 1 PMID:30100482 -3.2.1.40 * aspergillus aculeatus 13.0 13.0 1 PMID:11319105 -3.2.1.40 * aspergillus luchuensis 85.3 29.5 3 PMID:18633609 -3.2.1.40 * aspergillus nidulans 64.6 64.6 1 PMID:10972728 -3.2.1.40 * aspergillus niger 711.9 31.7 5 PMID:26769090;PMID:31161379;PMID:35366188;PMID:37160824;PMID:4632197 -3.2.1.40 * aspergillus oryzae 224.4 5.4 7 PMID:37160824;PMID:37818702 -3.2.1.40 * aspergillus terreus 454.0 453.0 2 PMID:29605638;PMID:34781207 -3.2.1.40 * bacillus sp. (in: firmicutes) 54.4 54.2 2 PMID:12831847 -3.2.1.40 * bacteroides jy-6 89.9 89.9 1 PMID:8996636 -3.2.1.40 * bacteroides thetaiotaomicron 0.57 0.57 1 PMID:37160824 -3.2.1.40 * bifidobacterium dentium 23.3 23.3 1 PMID:37160824 -3.2.1.40 * caldicellulosiruptor bescii 7.38 7.38 1 PMID:31685873 -3.2.1.40 * chloroflexus aurantiacus 304.3 54.2 9 PMID:30666483;PMID:37160824 -3.2.1.40 * dictyoglomus thermophilum 25.6 25.6 1 PMID:37160824 -3.2.1.40 * fusobacterium sp. 2.89 2.89 1 * -3.2.1.40 * lactiplantibacillus plantarum 64.7 64.7 3 PMID:34780892;PMID:37160824 -3.2.1.40 * novosphingobium sp. pp1y 5.9 5.9 1 PMID:37160824 -3.2.1.40 * paenibacillus odorifer 49.3 49.3 1 PMID:37160824 -3.2.1.40 * papiliotrema laurentii 29.89 29.89 1 PMID:35736128 -3.2.1.40 * penicillium decumbens 13.3 13.3 1 PMID:18754082 -3.2.1.40 * penicillium tardum 33.1 33.1 1 PMID:35670906 -3.2.1.40 * thermoclostridium stercorarium 82.0 1.5 3 PMID:10632887 -3.2.1.40 * thermoclostridium stercorarium subsp. stercorarium 2.13 2.13 1 PMID:31685873 -3.2.1.40 * thermomicrobia bacterium 263.9 186.39999999999998 2 * -3.2.1.40 * thermotoga maritima 40.5 40.5 3 PMID:31685873;PMID:37160824 -3.2.1.40 * thermotoga neapolitana 32.23 32.23 1 PMID:31685873 -3.2.1.40 * thermotoga petrophila 105.03 105.03 1 PMID:37160824 -3.2.1.40 * turbo cornutus 0.324 0.324 1 PMID:4632197 -3.2.1.41 * alkalihalophilus pseudofirmus 270.0 270.0 1 PMID:33547538 -3.2.1.41 * anoxybacillus ayderensis 10.0 10.0 1 PMID:33547538 -3.2.1.41 * anoxybacillus sp. wb42 66.7 66.7 1 PMID:31939086 -3.2.1.41 * aspergillus flavus 652.2 652.2 1 PMID:37482156 -3.2.1.41 * avena sativa 16.5 16.5 1 * -3.2.1.41 * bacillus acidopullulyticus 1096.0 200.0 5 PMID:18942837;PMID:30797482;PMID:33547538 -3.2.1.41 * bacillus cereus 44.7 44.7 1 PMID:33547538 -3.2.1.41 * bacillus methanolicus 292.0 238.0 4 PMID:32198062;PMID:33547538 -3.2.1.41 * bacillus safensis 13843.8 13843.8 1 PMID:36158107 -3.2.1.41 * bacillus sp. (in: firmicutes) 151.5 80.495 2 PMID:37587838 -3.2.1.41 * bacillus subtilis 136.06 80.08 2 PMID:16582490;PMID:31028806 -3.2.1.41 * desulfurococcus mucosus 26.0 26.0 2 PMID:11053376;PMID:33547538 -3.2.1.41 * geobacillus stearothermophilus 49.6 49.6 1 PMID:16347785 -3.2.1.41 * geobacillus thermocatenulatus 851.0 192.56 3 PMID:30222339;PMID:33547538 -3.2.1.41 * geobacillus thermoleovorans 36.0 12.0 3 PMID:18183386 -3.2.1.41 * laceyella sacchari 1352.0 1352.0 1 * -3.2.1.41 * metabacillus indicus 667.6 667.6 1 PMID:37119334 -3.2.1.41 * niallia circulans 84.2 84.2 1 * -3.2.1.41 * oryza sativa 16.5 16.5 1 * -3.2.1.41 * penicillium viridicatum 61.1 61.1 1 PMID:35879329 -3.2.1.41 * priestia megaterium 62.3 62.3 1 PMID:31065856 -3.2.1.41 * pyrococcus woesei 8.6 8.6 1 PMID:33547538 -3.2.1.41 * streptomyces erumpens 69.5 69.5 1 PMID:33547538 -3.2.1.41 * thermoanaerobacter thermohydrosulfuricus 481.0 481.0 1 PMID:3415657 -3.2.1.41 * thermoanaerobium sp. 1352.0 1352.0 1 * -3.2.1.41 * thermotoga neapolitana 28.7 28.7 1 PMID:22112909;PMID:33547538 -3.2.1.41 * thermus aquaticus 0.949 0.949 1 * -3.2.1.41 * zea mays 223.9 99.30000000000001 4 PMID:12234486 -3.2.1.42 * saccharomyces cerevisiae 0.208 0.208 1 PMID:5963308 -3.2.1.45 * homo sapiens 26.7 1.45 8 PMID:1070017;PMID:11087714;PMID:12734541;PMID:14757764;PMID:4014675;PMID:4768898;PMID:6166326 -3.2.1.45 * thermoanaerobacterium xylanolyticum 27.3 13.4 17 PMID:27115290 -3.2.1.46 * homo sapiens 0.12 0.12 1 PMID:507819 -3.2.1.46 * mus musculus 130.0 70.0 5 PMID:17403939;PMID:17986221 -3.2.1.48 * anser anser 2.95 2.95 1 PMID:2302412 -3.2.1.48 * bacillus subtilis 4.47 2.02 3 PMID:9573215 -3.2.1.48 * homo sapiens 47.0 1.3099999999999998 4 PMID:15236639;PMID:807575;PMID:8924896 -3.2.1.48 * mus musculus 17.5 17.5 1 PMID:1182172 -3.2.1.48 * oryctolagus cuniculus 17.5 8.8 2 PMID:1182172 -3.2.1.48 * platyrrhini 0.05 0.05 1 PMID:2113033 -3.2.1.48 * rattus rattus 9.5 1.46 3 PMID:2141837;PMID:6794628 -3.2.1.49 * arenibacter latericius 5.1 3.4 2 * -3.2.1.49 * arenibacter palladensis 1.83 1.33 2 * -3.2.1.49 * arenibacter sp. kmm 6041 0.84 0.84 1 * -3.2.1.49 * aspergillus niger 42.3 33.5 5 PMID:18443780;PMID:20601723;PMID:21982820 -3.2.1.49 * asterina amurensis 24.2 21.88 2 PMID:20139603 -3.2.1.49 * cellulophaga sp. 5.5 3.65 2 * -3.2.1.49 * clostridium perfringens 84110.0 84.11 3 PMID:11185964;PMID:14965778;PMID:15960079 -3.2.1.49 * formosa sp. kmm 6408 0.92 0.92 1 * -3.2.1.49 * gallus gallus 56.4 53.8 2 PMID:8954893 -3.2.1.49 * homo sapiens 2279.0 0.0023499999999999997 10 PMID:12062184;PMID:14767536;PMID:20139603 -3.2.1.49 * kriegella aquimaris 0.64 0.64 1 * -3.2.1.49 * maribacter sp. 1.38 0.7350000000000001 6 * -3.2.1.49 * zobellia laminariae 0.68 0.68 1 * -3.2.1.50 * bos taurus 0.0075 0.003825 2 PMID:4215452;PMID:5348072 -3.2.1.50 * clostridium perfringens 0.2 0.15000000000000002 2 PMID:21177247 -3.2.1.50 * homo sapiens 1.057 0.115 5 PMID:102578;PMID:10833408;PMID:11237686;PMID:8444316;PMID:949321 -3.2.1.50 * oryctolagus cuniculus 0.0012 0.0010999999999999998 2 PMID:6284758 -3.2.1.50 * patella vulgata 1.35 1.35 1 PMID:11946941 -3.2.1.50 * sus scrofa 0.027 0.027 1 PMID:4291567 -3.2.1.51 * bacillus fulminans 0.12 0.12 1 PMID:4781053 -3.2.1.51 * bacteroides fragilis 2.17 1.69 3 PMID:6250477 -3.2.1.51 * bos taurus 0.37 0.015 5 PMID:3729950;PMID:3942781 -3.2.1.51 * canis lupus lupus 14.9 14.9 1 PMID:10655154 -3.2.1.51 * chamelea gallina 1620.0 1620.0 1 PMID:7458 -3.2.1.51 * clostridium perfringens 2.61 2.61 1 PMID:19490 -3.2.1.51 * cricetulus griseus 64.8 64.8 1 PMID:7881175 -3.2.1.51 * dictyostelium discoideum 5.0 5.0 1 PMID:1310316 -3.2.1.51 * drosophila ananassae 0.911 0.911 1 PMID:16736526 -3.2.1.51 * emticicia oligotrophica 2.22 0.34 3 PMID:26941394 -3.2.1.51 * fusarium oxysporum 110.0 56.29 2 * -3.2.1.51 * homo sapiens 83.0 1.93 15 PMID:11389735;PMID:11870229;PMID:12127580;PMID:1260037;PMID:12604617;PMID:240814;PMID:39624;PMID:4844563;PMID:7054178;PMID:7356669 -3.2.1.51 * lacticaseibacillus casei 27.5 0.0525 10 PMID:21097595 -3.2.1.51 * limulus polyphemus 0.39 0.39 1 PMID:19490 -3.2.1.51 * mesocricetus auratus 0.025 0.025 1 PMID:8365108 -3.2.1.51 * mus musculus 5.84 5.84 1 PMID:3663178 -3.2.1.51 * niallia circulans 20.0 20.0 1 PMID:1694531 -3.2.1.51 * octopus vulgaris 38.9 38.9 1 PMID:7076646 -3.2.1.51 * paenibacillus thiaminolyticus 275.0 275.0 1 PMID:30544181 -3.2.1.51 * pecten maximus 86.0 86.0 1 PMID:12042250 -3.2.1.51 * pedobacter sp. cau209 26.3 23.05 2 PMID:32388762;PMID:37115252 -3.2.1.51 * penaeus monodon 31250.0 31250.0 1 PMID:1764918 -3.2.1.51 * penicillium multicolor 0.04 0.04 1 PMID:9720243 -3.2.1.51 * pomacea canaliculata 5.89 5.69 3 PMID:8470892 -3.2.1.51 * prunus dulcis 1.46 0.825 2 PMID:18111 -3.2.1.51 * rattus sp. 27.0 15.6 3 PMID:13077;PMID:19490;PMID:26840;PMID:5017763 -3.2.1.51 * saccharolobus solfataricus 32.1 32.1 1 PMID:12569098 -3.2.1.51 * sus scrofa 7.8 7.8 1 PMID:7317440 -3.2.1.51 * trypanosoma cruzi 0.03 0.016 2 PMID:12715078 -3.2.1.51 * wenyingzhuangia fucanilytica 2.99 2.99 1 PMID:27576198 -3.2.1.52 * aeromonas sp. 27.34 27.34 1 * -3.2.1.52 * akkermansia muciniphila 394.47 36.4 8 PMID:29304441;PMID:31345574;PMID:32819592;PMID:34922201 -3.2.1.52 * aspergillus flavipes 55.0 55.0 1 * -3.2.1.52 * aspergillus flavus 34.0 34.0 1 * -3.2.1.52 * aspergillus oryzae 49.0 49.0 1 * -3.2.1.52 * aspergillus parasiticus 21.0 21.0 1 * -3.2.1.52 * aspergillus sp. 2.2 2.2 1 PMID:17630125 -3.2.1.52 * aspergillus tamarii 30.0 30.0 1 * -3.2.1.52 * bacillus licheniformis 13.05 13.05 1 PMID:33776979 -3.2.1.52 * bacillus pumilus 5.91 5.91 1 PMID:30978418 -3.2.1.52 * bacillus sp. (in: firmicutes) 23.3 23.3 1 PMID:4628806 -3.2.1.52 * bipolaris sorokiniana 817.8 817.8 1 PMID:9812383 -3.2.1.52 * bombyx mori 362.9 211.75 2 PMID:990284 -3.2.1.52 * bos taurus 21.1 1.635 8 PMID:11148210;PMID:18192;PMID:4041463;PMID:5065953;PMID:6055190 -3.2.1.52 * brassica oleracea 9.737 9.737 1 PMID:9678259 -3.2.1.52 * caldicellulosiruptor acetigenus 568.1 11.2 4 PMID:34627844 -3.2.1.52 * canavalia ensiformis 101.9 101.9 1 PMID:5506280 -3.2.1.52 * candida albicans 4100.0 2205.0 2 PMID:3327914 -3.2.1.52 * capsicum annuum 10.11 9.71 2 PMID:12359515 -3.2.1.52 * carica papaya 12.9 12.9 1 * -3.2.1.52 * chitinibacter sp. gc72 333.33 81.34 7 PMID:35620090 -3.2.1.52 * citrullus lanatus 92.0 92.0 1 * -3.2.1.52 * cupiennius salei 15.85 15.85 1 PMID:7370275 -3.2.1.52 * dictyostelium discoideum 262.0 131.7 2 PMID:4607339 -3.2.1.52 * escherichia coli 162.3 162.3 1 PMID:1377 -3.2.1.52 * gallus gallus 84.7 68.4 3 * -3.2.1.52 * geobacillus stearothermophilus 11.7 11.7 1 PMID:8085829 -3.2.1.52 * halocynthia roretzi 214.1 214.1 1 PMID:6223923 -3.2.1.52 * helicella ericetorum 33.0 20.4 2 PMID:33660 -3.2.1.52 * homo sapiens 320.0 0.14150000000000001 16 PMID:17557860;PMID:1837501;PMID:2423070;PMID:6219664;PMID:758959;PMID:8400547 -3.2.1.52 * lactococcus lactis 37.0 28.05 2 PMID:22356128 -3.2.1.52 * lathyrus oleraceus 13.4 5.21 4 PMID:16665814 -3.2.1.52 * limulus polyphemus 0.067 0.067 1 PMID:885954 -3.2.1.52 * mizuhopecten yessoensis 42.5 42.5 1 PMID:7763885 -3.2.1.52 * mucor fragilis 35.2 24.700000000000003 2 PMID:16347047 -3.2.1.52 * mugil cephalus 21.3 21.3 1 PMID:2961751 -3.2.1.52 * octopus vulgaris 62.9 62.9 1 PMID:6852008 -3.2.1.52 * oryctolagus cuniculus 56.0 56.0 1 PMID:7283975 -3.2.1.52 * ostrinia furnacalis 25.0 12.5085 2 PMID:18959754 -3.2.1.52 * penaeus japonicus 123000.0 123000.0 1 PMID:9063965 -3.2.1.52 * penicillium oxalicum 186.0 126.0 3 * -3.2.1.52 * prunus serotina 184.2 184.2 1 * -3.2.1.52 * rattus norvegicus 2.8 0.94 9 PMID:1482400;PMID:34391;PMID:6055190 -3.2.1.52 * rhipicephalus microplus 77290.0 77290.0 1 PMID:10425723 -3.2.1.52 * saccharolobus solfataricus 7.5 7.5 1 PMID:24060745 -3.2.1.52 * serratia marcescens 4.36 4.36 1 PMID:12617608 -3.2.1.52 * sotalia fluviatilis 22.25 22.25 1 PMID:20349205 -3.2.1.52 * spodoptera frugiperda 0.035 0.019000000000000003 2 PMID:16684772 -3.2.1.52 * stachybotrys elegans 14.27 14.27 1 PMID:12030703 -3.2.1.52 * streptomyces alfalfae 1149.7 253.9 7 PMID:30782423 -3.2.1.52 * streptomyces avermitilis 24.0 9.97 7 PMID:34354524 -3.2.1.52 * streptomyces sp. 12.0 1.025 4 PMID:6808308 -3.2.1.52 * styela plicata 67.0 67.0 1 PMID:7118868 -3.2.1.52 * sus scrofa 46.7 25.900000000000002 2 PMID:2143152 -3.2.1.52 * trametes cinnabarina 67.0 67.0 1 PMID:7118868 -3.2.1.52 * tremella fuciformis 3.04 3.04 1 PMID:26672 -3.2.1.52 * trichinella spiralis 0.02908 0.00056 18 PMID:16242793 -3.2.1.52 * trichoderma harzianum 102.0 0.91 5 PMID:1368749 -3.2.1.52 * trichoderma virens 10698.0 10698.0 1 PMID:35578140 -3.2.1.52 * trichomonas vaginalis 2.432 2.412 3 PMID:11312579;PMID:15890491 -3.2.1.52 * trigonella foenum-graecum 25.68 4.585 4 PMID:25183 -3.2.1.52 * tritrichomonas suis 53.0 53.0 1 PMID:1212212 -3.2.1.52 * turbatrix aceti 90.0 90.0 1 PMID:6465897 -3.2.1.52 * verruciconidia persicina 5.64 3.283 2 PMID:33155 -3.2.1.53 * bacillus sp. (in: firmicutes) 15.4 15.4 1 PMID:9378710 -3.2.1.53 * rattus norvegicus 9.8 9.8 1 PMID:6222051 -3.2.1.54 * anoxybacillus flavithermus 3.5 3.5 1 PMID:15596360 -3.2.1.54 * archaeoglobus fulgidus 36.0 18.033 2 PMID:17921308 -3.2.1.54 * bacillus sp. (in: firmicutes) 148.0 148.0 1 PMID:9606956 -3.2.1.54 * escherichia coli 0.0424 0.0424 1 PMID:17494995 -3.2.1.54 * flavobacterium sp. 100.0 80.0 2 * -3.2.1.54 * flavobacterium sp. 92 36.1 36.1 1 PMID:19014948 -3.2.1.54 * geobacillus stearothermophilus 33.4 33.4 1 * -3.2.1.54 * geobacillus thermopakistaniensis 1200.0 735.0 3 PMID:31212108 -3.2.1.54 * heyndrickxia coagulans 0.12 0.12 1 * -3.2.1.54 * lactobacillus sp. 125.0 125.0 1 * -3.2.1.54 * lysinibacillus sphaericus 366.3 366.3 1 * -3.2.1.54 * more 5000.0 2600.0 9 PMID:17238236 -3.2.1.54 * niallia circulans 14.8 14.8 1 * -3.2.1.54 * paenibacillus macerans 175.0 90.0 2 PMID:4922856 -3.2.1.54 * pyrococcus furiosus 176.4 176.4 1 PMID:15466542 -3.2.1.54 * thermoanaerobacter thermohydrosulfuricus 62.0 38.25 2 PMID:1644767 -3.2.1.54 * thermococcus sp. 1940.0 1080.0 3 PMID:11489857 -3.2.1.54 * thermococcus sp. b1001 637.95 637.95 1 PMID:32738926 -3.2.1.54 * thermofilum pendens 535.1 356.05 2 PMID:19707756 -3.2.1.54 * thermotoga neapolitana 22.8 22.4 3 PMID:17399996 -3.2.1.54 * unidentified 30.7 3.4 5 PMID:16790023 -3.2.1.55 * acetivibrio thermocellus 5.0 2.15 8 PMID:24039988 -3.2.1.55 * agroathelia rolfsii 44.0 44.0 1 PMID:5143344 -3.2.1.55 * anoxybacillus kestanbolensis 1112.0 556.155 2 PMID:18679678 -3.2.1.55 * aspergillus awamori 3.85 2.495 2 PMID:37290707 -3.2.1.55 * aspergillus niger 396.6 388.6 5 PMID:1622210;PMID:5452669;PMID:7763988 -3.2.1.55 * aspergillus oryzae 32.0 32.0 1 * -3.2.1.55 * aspergillus sojae 69.5 69.5 1 * -3.2.1.55 * aspergillus terreus 76.6 50.4 3 * -3.2.1.55 * bacillus sp. (in: firmicutes) 27.7 27.7 1 PMID:26481625 -3.2.1.55 * bacillus subtilis 320.0 184.4 2 PMID:1622210;PMID:7944374 -3.2.1.55 * bifidobacterium breve 6.46 6.46 1 PMID:14660356 -3.2.1.55 * bifidobacterium dentium 71.4 3.84 13 PMID:34949752 -3.2.1.55 * bifidobacterium longum 71.36 37.0 2 PMID:21851513 -3.2.1.55 * butyrivibrio fibrisolvens 95.0 51.05 2 PMID:16348679;PMID:7887599 -3.2.1.55 * caldicellulosiruptor saccharolyticus 75.7 28.2 3 PMID:20477891;PMID:23568202 -3.2.1.55 * cellulosimicrobium aquatile 15.0 15.0 1 PMID:32535650 -3.2.1.55 * chaetomium sp. 20.6 20.6 1 * -3.2.1.55 * clostridium acetobutylicum 19.4 19.2 3 * -3.2.1.55 * evansstolkia leycettana 1068.0 1068.0 1 PMID:31426823 -3.2.1.55 * fusarium graminearum 1065.0 589.0 2 PMID:19269961 -3.2.1.55 * fusarium oxysporum 10.0 6.42 3 PMID:10949693;PMID:14663498 -3.2.1.55 * fusarium oxysporum f. sp. dianthi 1.07 1.07 1 * -3.2.1.55 * geobacillus stearothermophilus 749.1 113.5 4 PMID:7887599 -3.2.1.55 * geobacillus vulcani 72.066 72.066 1 PMID:30334285 -3.2.1.55 * glycine max 95.2 95.2 1 * -3.2.1.55 * halothermothrix orenii 0.036 0.0265 2 PMID:25760712 -3.2.1.55 * hordeum vulgare 6610.0 6.3 3 PMID:11054116;PMID:11336650;PMID:12464603 -3.2.1.55 * kuraishia capsulata 36.3 36.3 1 PMID:10923788 -3.2.1.55 * lacrimispora xylanisolvens 108.0 108.0 1 * -3.2.1.55 * monilinia fructigena 9.4 8.5 2 PMID:3663195 -3.2.1.55 * paenibacillus curdlanolyticus 0.3 0.2 2 PMID:27663030 -3.2.1.55 * paenibacillus sp. 96.7 14.4 3 PMID:24248090;PMID:27398094 -3.2.1.55 * paenibacillus xylaniclasticus 0.31 0.31 1 PMID:36312872 -3.2.1.55 * pectobacterium carotovorum 40.0 40.0 1 * -3.2.1.55 * penicillium chrysogenum 13.5 9.65 2 PMID:12726996 -3.2.1.55 * penicillium parvum 94.1 21.2 5 PMID:32880690;PMID:34933174 -3.2.1.55 * penicillium subrubescens 507.9 14.6 9 PMID:35014696 -3.2.1.55 * phanerodontia chrysosporium 197.0 197.0 1 PMID:23474097 -3.2.1.55 * pleurotus ostreatus 36.7 36.7 1 PMID:24565609 -3.2.1.55 * pyrus pyrifolia 5.25 5.25 1 PMID:15965025 -3.2.1.55 * rhodotorula flava 32.5 32.5 1 PMID:25260 -3.2.1.55 * ruminiclostridium josui 2300.0 1020.0 4 PMID:30037546 -3.2.1.55 * ruminococcus albus 655.5 655.5 1 PMID:1622210;PMID:6742828 -3.2.1.55 * saccharolobus solfataricus 3.63 3.63 1 PMID:17033733 -3.2.1.55 * saccharomycopsis fibuligera 97.7 9.65 18 PMID:33397826 -3.2.1.55 * scopolia japonica 611.0 611.0 1 * -3.2.1.55 * spinacia oleracea 2.5 1.555 2 * -3.2.1.55 * streptomyces avermitilis 2.92 2.92 1 PMID:18665359 -3.2.1.55 * streptomyces chartreusis 10.4 6.78 2 PMID:10657233 -3.2.1.55 * streptomyces diastaticus 131.2 118.1 2 PMID:1622210 -3.2.1.55 * streptomyces lividans 153.0 153.0 1 * -3.2.1.55 * streptomyces purpurascens 82.9 82.9 1 * -3.2.1.55 * streptomyces sp. 3.4 3.4 1 PMID:1622210 -3.2.1.55 * streptomyces sp. swu10 1.29 0.665 2 PMID:29499776 -3.2.1.55 * talaromyces funiculosus 1.0 1.0 1 PMID:24731829 -3.2.1.55 * talaromyces purpureogenus 89.5 0.10500000000000001 12 PMID:10656340;PMID:18550352;PMID:20562284 -3.2.1.55 * thermobacillus xylanilyticus 490.0 169.0 11 PMID:10742272;PMID:11842234;PMID:15261595;PMID:15721334;PMID:18563919 -3.2.1.55 * thermobifida fusca 0.00014 0.00014 1 PMID:12800498 -3.2.1.55 * thermoclostridium stercorarium 883.0 883.0 1 PMID:7576552 -3.2.1.55 * thermomicrobia bacterium 0.6 0.28 4 PMID:15604762 -3.2.1.55 * thermomyces dupontii 49.0 25.4 2 * -3.2.1.55 * thermothielavioides terrestris 83.39 16.51 6 PMID:32866628;PMID:32880690 -3.2.1.55 * trichoderma reesei 196.0 61.3 4 PMID:10473402 -3.2.1.55 * trichoderma sp. 239.9 239.9 1 * -3.2.1.56 * pedobacter heparinus 259.0 39.7 4 PMID:4730325;PMID:8526872;PMID:921751 -3.2.1.57 * aspergillus niger 480.0 27.15 4 PMID:12834298;PMID:4650606;PMID:8987855 -3.2.1.57 * bacillus sp. (in: firmicutes) 9.6 9.6 1 * -3.2.1.58 * abracris flavolineata 1.89 1.89 1 PMID:17720633 -3.2.1.58 * achlya bisexualis 7840.0 7840.0 1 * -3.2.1.58 * aplysia kurodai 3.0 3.0 1 PMID:19883786 -3.2.1.58 * basidiomycota 400.0 400.0 1 * -3.2.1.58 * candida albicans 215.0 65.0 3 PMID:2515245;PMID:8348966;PMID:8436950 -3.2.1.58 * cellulomonas fimi 19.4 19.4 1 PMID:25797391 -3.2.1.58 * coccidioides immitis 52.1 52.1 1 PMID:1398946 -3.2.1.58 * coprinopsis cinerea 4481.0 2848.0 9 PMID:26199012 -3.2.1.58 * cyberlindnera jadinii 20.7 20.7 1 PMID:1033777 -3.2.1.58 * cyberlindnera saturnus 1966.0 380.0 4 PMID:19513709;PMID:20336338 -3.2.1.58 * fungi imperfecti 169.4 169.4 1 * -3.2.1.58 * helix pomatia 24.2 24.2 1 PMID:236727 -3.2.1.58 * hordeum vulgare 12.8 4.7 3 PMID:8617814;PMID:9097482 -3.2.1.58 * kluyveromyces aestuarii 250.0 250.0 1 PMID:20206 -3.2.1.58 * komagataella pastoris 13.77 13.77 1 PMID:16427312 -3.2.1.58 * neurospora crassa 0.845 0.845 1 * -3.2.1.58 * penicillium sp. kh10 11.7 11.7 1 PMID:19500674 -3.2.1.58 * porodisculus pendulus 27.7 27.7 1 * -3.2.1.58 * rasamsonia emersonii 592.0 592.0 1 PMID:20882275 -3.2.1.58 * rhizoctonia solani 0.265 0.265 1 PMID:19022284 -3.2.1.58 * rhizomucor miehei 19.1 19.1 1 PMID:25577102 -3.2.1.58 * saccharomyces cerevisiae 13.2 2.5 3 PMID:2500920;PMID:6820801 -3.2.1.58 * schizosaccharomyces japonicus 180.0 180.0 1 PMID:1093 -3.2.1.58 * streptomyces murinus 6.7 6.7 1 * -3.2.1.58 * thermochaetoides thermophila 45.4 45.4 1 * -3.2.1.58 * trichoderma asperellum 7.75 0.008 7 PMID:12594027;PMID:18804353 -3.2.1.58 * trichoderma harzianum 593.0 299.4 2 * -3.2.1.58 * trichoderma reesei 612.0 612.0 1 PMID:7197155 -3.2.1.58 * trichoderma viride 63.0 63.0 1 PMID:11733006 -3.2.1.58 * uncultured bacterium 142.5 49.8 10 PMID:33375982 -3.2.1.58 * verruciconidia persicina 335.0 292.0 3 PMID:8948426 -3.2.1.59 * flavobacterium sp. 0.831 0.831 1 PMID:370 -3.2.1.59 * niallia circulans 11.2 9.36 2 * -3.2.1.59 * pseudomonas sp. 78.1 78.1 1 PMID:7074138 -3.2.1.59 * streptomyces chartreusis 0.968 0.968 1 PMID:7462159 -3.2.1.6 * acetivibrio thermocellus 2.83 0.4 3 * -3.2.1.6 * aplysia kurodai 172.0 172.0 1 PMID:19883786 -3.2.1.6 * bacillus licheniformis 6900.0 2479.0 3 PMID:16470364;PMID:24391357 -3.2.1.6 * bacillus subtilis 728.8 553.95 2 PMID:18365147 -3.2.1.6 * bacteroides fragilis 0.13 0.13 1 PMID:879772 -3.2.1.6 * bacteroides thetaiotaomicron 0.12 0.12 1 PMID:879772 -3.2.1.6 * caldicellulosiruptor sp. f32 2961.0 1566.5 2 PMID:26837217 -3.2.1.6 * cellulosimicrobium funkei 6.2 4.5 2 PMID:26481128 -3.2.1.6 * cherax destructor 18.31 3.845 4 PMID:18587122 -3.2.1.6 * coprinopsis cinerea 118.8 55.949999999999996 4 PMID:28007217 -3.2.1.6 * cyberlindnera jadinii 0.0005 0.0005 1 PMID:570837 -3.2.1.6 * flavobacterium dormitator 25.0 1.38 5 PMID:1368600 -3.2.1.6 * haliotis discus hannai 68.0 68.0 1 PMID:19446649 -3.2.1.6 * kluyveromyces lactis 0.013 0.013 1 PMID:5141672 -3.2.1.6 * lysobacter enzymogenes 23.4 23.4 1 * -3.2.1.6 * mycothermus thermophilus 693.0 693.0 1 PMID:26611612 -3.2.1.6 * paenibacillus sp. 2.22 2.22 1 PMID:25391729 -3.2.1.6 * parabacteroides distasonis 0.03 0.03 1 PMID:879772 -3.2.1.6 * pseudocardium sachalinense 350.0 350.0 1 PMID:5500926 -3.2.1.6 * rasamsonia emersonii 1963.0 1807.5 2 PMID:11427240 -3.2.1.6 * rhizoctonia solani 66.0 66.0 1 * -3.2.1.6 * saccharomyces cerevisiae 0.4 0.4 1 * -3.2.1.6 * streptococcus equinus jb1 338.3 303.5 3 PMID:9327538 -3.2.1.6 * streptomyces sp. 58.0 58.0 1 PMID:26888054 -3.2.1.6 * thermothelomyces heterothallicus 56.0 34.5 4 PMID:25869365 -3.2.1.60 * bacillus sp. (in: firmicutes) 158.0 158.0 1 PMID:16535108 -3.2.1.60 * pseudomonas sp. 1775.0 1659.5 2 PMID:9827329 -3.2.1.60 * roseateles saccharophilus 1802.0 1501.0 2 PMID:36238980 -3.2.1.60 * stutzerimonas stutzeri 2590.0 313.0 5 PMID:1368535;PMID:5123132 -3.2.1.61 * niallia circulans 7.88 7.88 1 * -3.2.1.61 * penicillium melinii 27.0 27.0 1 PMID:4108250 -3.2.1.61 * streptomyces sp. 2.53 2.53 1 PMID:1368944 -3.2.1.62 * homo sapiens 32.0 0.00334 11 PMID:17506819;PMID:17595169;PMID:6786877 -3.2.1.62 * macaca radiata 16.1 5.0 3 PMID:4200393;PMID:810166 -3.2.1.62 * mus musculus 15.33 0.0025 7 PMID:17595169;PMID:6790523 -3.2.1.62 * oryctolagus cuniculus 4.8 4.8 1 PMID:1388157 -3.2.1.62 * rattus norvegicus 0.00133 0.000915 2 PMID:17595169 -3.2.1.62 * rattus sp. 22.0 21.0 2 PMID:4752949;PMID:6775701 -3.2.1.63 * aspergillus niger 6.7 6.7 1 PMID:5460888 -3.2.1.63 * bacillus cereus 51.1 51.1 1 PMID:16233842 -3.2.1.63 * bacillus fulminans 0.12 0.12 1 PMID:4781053 -3.2.1.63 * bacteroides caccae 2.9 1.9449999999999998 2 PMID:35943155 -3.2.1.63 * clostridium perfringens 70.0 70.0 1 PMID:4314593 -3.2.1.63 * phocaeicola vulgatus 0.89 0.89 1 PMID:35943155 -3.2.1.63 * prunus dulcis 0.00186 0.00186 1 PMID:18111 -3.2.1.64 * microbacterium laevaniformans 997.3 997.3 1 PMID:12095678 -3.2.1.64 * streptomyces exfoliatus 105.0 105.0 1 PMID:10618232 -3.2.1.65 * actinomyces viscosus 851.0 851.0 1 PMID:3679542 -3.2.1.65 * arthrobacter sp. 500.0 500.0 1 * -3.2.1.65 * azotobacter chroococcum 6685.0 6685.0 1 PMID:33436213 -3.2.1.65 * bacillus licheniformis 987.0 37.9 3 PMID:25107977 -3.2.1.65 * bacillus sp. l7 128.0 128.0 1 PMID:9297817 -3.2.1.65 * bacillus subtilis 97.4 0.4 3 PMID:3112519;PMID:7646030 -3.2.1.65 * belliella baltica 109.2 93.25 3 PMID:36826427 -3.2.1.65 * capnocytophaga ochracea 137.79 102.79 3 PMID:36826427 -3.2.1.65 * dyadobacter fermentans 98.51 93.0 3 PMID:36826427 -3.2.1.65 * gluconacetobacter diazotrophicus 58.0 14.24 3 PMID:19139238 -3.2.1.65 * lacticaseibacillus casei 0.5 0.5 1 PMID:7612248 -3.2.1.65 * lactiplantibacillus plantarum 0.09 0.09 1 PMID:7612248 -3.2.1.65 * paenarthrobacter aurescens 329.83 121.67 3 PMID:36826427 -3.2.1.65 * priestia koreensis 2.43 2.43 1 PMID:35931938 -3.2.1.65 * pseudomonas sp. k-52 39.2 39.2 1 PMID:9569612 -3.2.1.65 * pseudomonas sp. no. 43 30.5 30.5 1 * -3.2.1.65 * rhodotorula sp. 34.4 34.4 1 PMID:8672285 -3.2.1.65 * streptococcus salivarius 810.0 810.0 1 PMID:6618666 -3.2.1.65 * streptomyces sp. 366l 4309.0 4309.0 1 * -3.2.1.65 * uncultured bacterium 226.7 226.7 1 PMID:23732333 -3.2.1.65 * vibrio natriegens 66.67 65.68 3 PMID:36826427 -3.2.1.67 * aspergillus fumigatus 5.72 1.44 3 PMID:36788465 -3.2.1.67 * aspergillus giganteus 419.4 419.4 1 PMID:20204453 -3.2.1.67 * aspergillus neoglaber 555.0 555.0 1 PMID:34274400 -3.2.1.67 * aspergillus niger 418.6 26.99 11 PMID:12204327;PMID:18500582;PMID:23069766;PMID:2310 -3.2.1.67 * bacillus sp. (in: firmicutes) 54.0 28.43 2 PMID:11388462;PMID:5661621 -3.2.1.67 * botrytis cinerea 0.6 0.6 1 PMID:12398287 -3.2.1.67 * butyrivibrio fibrisolvens 5.45 3.575 2 PMID:4056742 -3.2.1.67 * colletotrichum lindemuthianum 183.0 93.25 2 * -3.2.1.67 * daucus carota 0.69 0.5 4 * -3.2.1.67 * fusarium oxysporum 31.49 20.145 2 * -3.2.1.67 * fusarium oxysporum f. sp. cubense 105.26 105.26 1 PMID:32717856 -3.2.1.67 * klebsiella sp. y1 47.0 47.0 1 PMID:22940315 -3.2.1.67 * marchantia polymorpha 4.74 2.41 2 PMID:16663197 -3.2.1.67 * paecilomyces variotii 298.5 98.49 3 PMID:19484410;PMID:23729888 -3.2.1.67 * penicillium expansum 12860.0 6432.68 2 PMID:19968548 -3.2.1.67 * penicillium janthinellum 110.5 110.5 1 PMID:31461202 -3.2.1.67 * penicillium oxalicum 5.63 5.63 1 PMID:35207571 -3.2.1.67 * penicillium viridicatum 356.7 351.54999999999995 2 PMID:20148174 -3.2.1.67 * rhizomucor pusillus 171.0 171.0 1 PMID:28025649 -3.2.1.67 * rhizopus arrhizus 60.5 60.5 1 * -3.2.1.67 * serendipita indica 479.09 341.485 2 * -3.2.1.67 * solanum lycopersicum 35.3 35.3 1 * -3.2.1.67 * thermoascus aurantiacus 5352.0 5352.0 1 PMID:24159381 -3.2.1.67 * zea mays 16.0 16.0 1 * -3.2.1.68 * bacillus sp. (in: firmicutes) 469.0 469.0 1 * -3.2.1.68 * flavobacterium sp. 182.0 137.0 8 PMID:9197405 -3.2.1.68 * lipomyces kononenkoae 52.0 52.0 1 PMID:16346143 -3.2.1.68 * oryza sativa 51.2 51.2 1 PMID:10333591 -3.2.1.68 * phaseolus vulgaris 29.05 7.765 12 PMID:17827690 -3.2.1.68 * pseudomonas sp. 'amyloderamosa' 190.0 59.1 3 PMID:5456995 -3.2.1.68 * rhizopus arrhizus 138.37 109.54499999999999 4 PMID:31868558 -3.2.1.68 * solanum tuberosum 8.0 8.0 1 * -3.2.1.7 * arthrobacter sp. 53.0 53.0 1 * -3.2.1.7 * aspergillus fumigatus 1520.0 771.5 2 PMID:16171693;PMID:25369893 -3.2.1.7 * aspergillus neotritici 57.86 31.345 2 PMID:32890562 -3.2.1.7 * aspergillus niger 1206.63 32.0 5 PMID:22813590;PMID:28732903 -3.2.1.7 * bacillus smithii 1105.0 570.11 2 PMID:18663416 -3.2.1.7 * kluyveromyces marxianus 0.2416 0.13615 4 PMID:18592410 -3.2.1.7 * lipomyces starkeyi 2262.82 2262.82 1 PMID:31233793 -3.2.1.7 * penicillium sp. 105.0 105.0 1 * -3.2.1.7 * pseudogymnoascus pannorum 106.2 106.2 1 * -3.2.1.7 * xanthomonas oryzae 1407.0 1407.0 1 * -3.2.1.7 * xanthomonas phaseoli pv. phaseoli 174.74 174.74 1 PMID:27904343 -3.2.1.70 * arthrobacter globiformis 25.6 25.6 1 * -3.2.1.70 * brevibacterium fuscum var. dextranlyticum 34.3 34.3 1 PMID:4210084;PMID:856322 -3.2.1.70 * lactobacillus acidophilus 335.0 335.0 1 PMID:22685275 -3.2.1.70 * lipomyces lipofer 50.0 50.0 1 PMID:6193756 -3.2.1.70 * streptococcus mitis 34.3 34.3 1 PMID:4210084;PMID:856322 -3.2.1.73 * acetivibrio thermocellus 2434.0 1010.5 4 PMID:21735259 -3.2.1.73 * bacillus altitudinis 5393.0 3883.0 2 PMID:23292246 -3.2.1.73 * bacillus amyloliquefaciens 3722.0 1746.0 9 PMID:21735259;PMID:25048240;PMID:2673278 -3.2.1.73 * bacillus licheniformis 8231.0 1280.0 9 PMID:16470364;PMID:17216453;PMID:22653681;PMID:24397427 -3.2.1.73 * bacillus pumilus 161.0 115.7 2 PMID:27838418 -3.2.1.73 * bacillus sp. (in: firmicutes) 1329.0 1329.0 1 PMID:7222749 -3.2.1.73 * bacillus subtilis 555.1 82.45 3 PMID:18350387;PMID:34409950 -3.2.1.73 * bacillus tequilensis 7500.0 3213.0 4 PMID:24728764;PMID:27100881;PMID:27627900 -3.2.1.73 * bacillus velezensis 15.9 15.9 1 PMID:26589782 -3.2.1.73 * bispora sp. 4040.0 3390.0 2 PMID:19590866 -3.2.1.73 * chaetomium sp. cq31 999.9 938.7 3 PMID:34329700 -3.2.1.73 * fibrobacter succinogenes 10800.0 2065.0 11 PMID:11279139;PMID:12093295;PMID:15966744;PMID:17694302;PMID:19018102;PMID:19714803;PMID:20635417;PMID:21959377;PMID:3063255 -3.2.1.73 * hordeum vulgare 14.5 14.5 1 PMID:11391016 -3.2.1.73 * laetiporus sulphureus 29.0 29.0 1 PMID:19734720 -3.2.1.73 * macrotermes barneyi 16.7 16.7 1 PMID:32725373 -3.2.1.73 * malbranchea cinnamomea 77.7 47.95 4 PMID:25113013 -3.2.1.73 * neocallimastix patriciarum 41210.0 35810.0 4 PMID:22492445 -3.2.1.73 * orpinomyces sp. 3659.0 3659.0 1 PMID:9324248 -3.2.1.73 * oryza sativa 387.0 387.0 1 * -3.2.1.73 * paecilomyces sp. 6242.0 3146.45 2 PMID:18543932 -3.2.1.73 * paecilomyces sp. 'thermophila' 11940.0 10074.0 2 PMID:20645085 -3.2.1.73 * paenibacillus barengoltzii 431.8 431.8 1 PMID:28551269 -3.2.1.73 * paenibacillus macerans 5030.0 3722.0 3 PMID:2673278 -3.2.1.73 * paenibacillus polymyxa 1605.1 721.1 6 PMID:16912849 -3.2.1.73 * paenibacillus sp. 7055.0 3528.61 2 PMID:24322768;PMID:25391729 -3.2.1.73 * paenibacillus sp. x4 607.0 607.0 1 PMID:28180917 -3.2.1.73 * penicillium occitanis (nom. inval.) 41.66 41.66 1 * -3.2.1.73 * rhizomucor miehei 28820.0 28820.0 1 PMID:22309761 -3.2.1.73 * rhizopus microsporus 12.6 6.398499999999999 2 PMID:17147821 -3.2.1.73 * thermoascus aurantiacus 13527.0 12502.0 3 PMID:30216845 -3.2.1.73 * thermomonospora sp. 792.2 311.8 4 PMID:17689169 -3.2.1.73 * uncultured bacterium 24.0 24.0 1 PMID:30123929 -3.2.1.73 * uncultured microorganism 58.6 54.3 3 PMID:21455595;PMID:25152058 -3.2.1.73 * uncultured paecilomyces 85.3 85.3 1 PMID:30268756 -3.2.1.74 * alternaria sp. 4.1 2.4 3 PMID:25784958 -3.2.1.74 * arthrinium sp. 9.5 2.85 8 PMID:25784958 -3.2.1.74 * aspergillus sp. 1.7 1.5499999999999998 4 PMID:25784958 -3.2.1.74 * aureobasidium sp. 2.9 2.35 2 PMID:25784958 -3.2.1.74 * bipolaris sp. 1.9 1.6 3 PMID:25784958 -3.2.1.74 * caldicellulosiruptor bescii 0.285 0.285 1 PMID:9493383 -3.2.1.74 * cephalosporium sp. 13.2 4.55 4 PMID:25784958 -3.2.1.74 * chaetomium globosum 3.583 2.945 4 PMID:12916726 -3.2.1.74 * chloridium sp. 1.2 0.8 4 PMID:25784958 -3.2.1.74 * cladosporium sp. 1.1 0.7 4 PMID:25784958 -3.2.1.74 * clostridium cellulovorans 177.0 130.0 5 PMID:16930544 -3.2.1.74 * cordyceps sp. 3.3 2.2 4 PMID:25784958 -3.2.1.74 * dothideomycetes sp. 22.6 9.8 4 PMID:25784958 -3.2.1.74 * epicoccum sp. 12.2 9.4 4 PMID:25784958 -3.2.1.74 * exophiala sp. 2.3 0.25 4 PMID:25784958 -3.2.1.74 * fibrobacter succinogenes subsp. succinogenes s85 0.275 0.25 3 PMID:18203823 -3.2.1.74 * fusarium sp. 2.2 0.9 5 PMID:25784958 -3.2.1.74 * gecarcoidea natalis 0.228 0.14750000000000002 2 PMID:20709923 -3.2.1.74 * irpex lacteus 34.0 14.5 21 PMID:16232497;PMID:16233004 -3.2.1.74 * microdochium sp. 1.8 1.05 4 PMID:25784958 -3.2.1.74 * minimidochium sp. tms-2011 0.8 0.5 4 PMID:25784958 -3.2.1.74 * mycothermus thermophilus 8.09 2.57 3 * -3.2.1.74 * nakazawaea wickerhamii 276.7 276.7 1 PMID:3093475 -3.2.1.74 * neurospora crassa 12.4 6.7 4 PMID:25784958 -3.2.1.74 * nigrospora sp. 1.8 1.4500000000000002 4 PMID:25784958 -3.2.1.74 * penicillium sp. 8.4 5.35 4 PMID:25784958 -3.2.1.74 * phanerodontia chrysosporium 5.1 3.25 2 PMID:25784958 -3.2.1.74 * phoma sp. 1.2 0.8 3 PMID:25784958 -3.2.1.74 * rhodonia placenta 2.1 1.7 3 PMID:25784958 -3.2.1.74 * ruminiclostridium papyrosolvens 30.94 30.94 1 PMID:9569613 -3.2.1.74 * ruminococcus albus 13.0 9.5 2 PMID:2119579 -3.2.1.74 * sporothrix sp. 2.4 1.9 2 PMID:25784958 -3.2.1.74 * talaromyces funiculosus 7.0 7.0 1 * -3.2.1.74 * thermoclostridium stercorarium 0.684 0.108 11 PMID:1909625 -3.2.1.74 * thermomonospora sp. 58.79 58.79 1 PMID:15721281 -3.2.1.74 * trichoderma reesei 2.2 1.7 4 PMID:25784958 -3.2.1.74 * trichoderma sp. 23.3 1.9000000000000001 8 PMID:25784958 -3.2.1.74 * uncultured bacterium 717.0 52.9 7 * -3.2.1.74 * uncultured rumen bacterium 77.0 18.75 8 PMID:22020745 -3.2.1.74 * vibrio cholerae serotype o1 0.323 0.323 1 PMID:12042307 -3.2.1.75 * chlamys albidus 1.654 1.654 1 * -3.2.1.75 * flavobacterium m64 0.22 0.22 1 * -3.2.1.75 * mucor hiemalis 5.18 5.18 1 PMID:947537 -3.2.1.75 * neotyphodium sp. 0.48 0.48 1 PMID:12427996 -3.2.1.75 * neurospora crassa 13.4 13.4 1 * -3.2.1.75 * niallia circulans 131.2 131.2 1 PMID:4407251 -3.2.1.75 * penicillium brefeldianum 405.0 405.0 1 PMID:6508737 -3.2.1.75 * penicillium multicolor 164.1 164.1 1 PMID:23246473 -3.2.1.75 * rhizopus microsporus var. chinensis 0.7 0.7 1 * -3.2.1.75 * saccharomycopsis fibuligera 75.4 40.2 2 PMID:7891593 -3.2.1.75 * streptomyces rochei 83.3 83.3 1 PMID:12507000 -3.2.1.75 * trichoderma harzianum 204.0 188.0 3 PMID:10491168;PMID:15982190;PMID:9795258 -3.2.1.75 * verruciconidia persicina 146.0 146.0 1 PMID:8670160 -3.2.1.76 * canis sp. 126000.0 126000.0 1 PMID:1551868 -3.2.1.76 * homo sapiens 5000.0 16.0 17 PMID:15300847;PMID:16439176;PMID:17177794;PMID:23786846;PMID:2470345;PMID:30407;PMID:4043081;PMID:6421818;PMID:7098949;PMID:7950365 -3.2.1.76 * mus musculus 5e-06 5e-06 1 PMID:24332804 -3.2.1.76 * sus scrofa 34.9 34.9 1 PMID:2917561 -3.2.1.78 * aeromonas hydrophila 201.0 201.0 1 * -3.2.1.78 * agroathelia rolfsii 475.0 427.5 2 * -3.2.1.78 * aplysia kurodai 27.4 27.4 1 PMID:20639136 -3.2.1.78 * aspergillus aculeatus 2037.4 848.5999999999999 6 PMID:11162394;PMID:33644418;PMID:7987261 -3.2.1.78 * aspergillus fischeri 1703.0 1703.0 1 PMID:25466024 -3.2.1.78 * aspergillus fumigatus 751.0 305.5 14 PMID:15541293;PMID:19205049 -3.2.1.78 * aspergillus niger 1139.0 416.75 4 PMID:19884778;PMID:21632240 -3.2.1.78 * aspergillus sulphureus 366.0 366.0 1 PMID:17194495 -3.2.1.78 * bacillus licheniformis 1672.0 1672.0 1 PMID:20380743 -3.2.1.78 * bacillus sp. (in: firmicutes) 5383.0 2926.5 2 PMID:19263048 -3.2.1.78 * bacillus sp. swu60 14.0 7.15 2 PMID:28220352 -3.2.1.78 * bacillus subtilis 8302.0 1592.5 8 PMID:17294696;PMID:21636987;PMID:22450788 -3.2.1.78 * bacillus velezensis 3809.52 3809.52 1 PMID:37691038 -3.2.1.78 * bispora sp. 3373.0 3373.0 1 PMID:18998121 -3.2.1.78 * cellulomonas fimi 3.1 1.54 4 PMID:16171384 -3.2.1.78 * cellulosimicrobium sp. 14710.0 11604.0 2 PMID:21767948 -3.2.1.78 * clostridium cellulovorans 18.5 12.2 3 PMID:21311881 -3.2.1.78 * coffea arabica 1400.0 1400.0 1 PMID:11469596 -3.2.1.78 * coprinopsis cinerea 312.68 312.68 1 PMID:36983546 -3.2.1.78 * cryptopygus antarcticus 416.3 416.3 1 PMID:18579426 -3.2.1.78 * cyamopsis tetragonoloba 125.0 125.0 1 * -3.2.1.78 * dictyoglomus turgidum 215.0 215.0 1 PMID:29177717 -3.2.1.78 * haliotis discus hannai 11.48 9.6 3 PMID:16621092 -3.2.1.78 * infundibulicybe geotropa 83.81 42.1425 2 * -3.2.1.78 * klebsiella oxytoca 11900.0 2450.0 3 PMID:29378260;PMID:34726170 -3.2.1.78 * niallia circulans 4839.0 2660.25 2 PMID:18239434;PMID:18820840 -3.2.1.78 * penicillium freii 47.5 47.5 1 PMID:22382013 -3.2.1.78 * penicillium occitanis (nom. inval.) 129.3 129.3 1 PMID:19418261 -3.2.1.78 * penicillium oxalicum 420.9 420.9 1 PMID:25348022 -3.2.1.78 * reinekea sp. kit-yo10 236.0 236.0 1 PMID:25036974 -3.2.1.78 * rhizomucor miehei 10760.0 10760.0 1 PMID:23252695 -3.2.1.78 * talaromyces purpureogenus 21.0 21.0 1 * -3.2.1.78 * thermothelomyces thermophilus 312.0 220.0 3 PMID:27193267 -3.2.1.78 * verrucomicrobiia bacterium dg1235 188.5 173.1 2 PMID:33439094 -3.2.1.78 * weissella viridescens 63.94 32.14 2 PMID:30031310 -3.2.1.8 * acetivibrio thermocellus 34.0 31.0 3 * -3.2.1.8 * acidothermus cellulolyticus 1833.0 1833.0 1 PMID:29170828 -3.2.1.8 * acrophialophora nainiana 31.25 31.25 1 PMID:12829303 -3.2.1.8 * alternaria sp. 2906.0 1247.5 4 PMID:25784958 -3.2.1.8 * arthrinium sp. 3525.0 1918.0 8 PMID:25784958 -3.2.1.8 * arthrobacter sp. 1266.0 1205.5 6 * -3.2.1.8 * aspergillus flavus 838.2 610.8 2 PMID:30316914;PMID:30747436 -3.2.1.8 * aspergillus fumigatus 38200.0 75.0 3 PMID:26847222 -3.2.1.8 * aspergillus japonicus 566.0 566.0 1 PMID:20159568 -3.2.1.8 * aspergillus luchuensis 350.0 350.0 1 PMID:26686608 -3.2.1.8 * aspergillus nidulans 378.0 378.0 1 * -3.2.1.8 * aspergillus niger 22250.0 513.55 10 PMID:15063320;PMID:17445930;PMID:20361933;PMID:23241981;PMID:23670313;PMID:24888408 -3.2.1.8 * aspergillus sp. 2740.0 1816.5 4 PMID:25784958 -3.2.1.8 * aspergillus versicolor 302.0 302.0 1 * -3.2.1.8 * aureobasidium melanogenum 103.9 61.86 2 PMID:35132493 -3.2.1.8 * aureobasidium sp. 1489.0 872.0 4 PMID:25784958 -3.2.1.8 * bacillus amyloliquefaciens 213.1 213.1 1 * -3.2.1.8 * bacillus licheniformis 720.0 367.0 3 PMID:16915648 -3.2.1.8 * bacillus pumilus 1780.0 1039.0 2 * -3.2.1.8 * bacillus sp. (in: firmicutes) 1436.0 312.0 5 PMID:10830514;PMID:19911836 -3.2.1.8 * bacillus subtilis 5890.0 1.73 8 PMID:17445930;PMID:26923808;PMID:27097633 -3.2.1.8 * bipolaris sp. 325.0 59.0 4 PMID:25784958 -3.2.1.8 * bispora sp. mey-1 18830.0 2144.0 5 PMID:19655217;PMID:20077114 -3.2.1.8 * caldicellulosiruptor saccharolyticus 167.0 167.0 1 PMID:8467959 -3.2.1.8 * cellulomonas fimi 31.3 2.43 3 * -3.2.1.8 * cellulomonas flavigena 24300.0 12311.0 2 * -3.2.1.8 * cellulosimicrobium sp. 21.2 14.9 5 PMID:18027102 -3.2.1.8 * cephalosporium sp. 2997.0 2476.0 4 PMID:25784958 -3.2.1.8 * chloridium sp. 992.0 815.5 4 PMID:25784958 -3.2.1.8 * cladosporium sp. 774.0 738.0 5 PMID:25784958;PMID:30115321 -3.2.1.8 * clostridium acetobutylicum 6.59 5.995 2 PMID:16347312 -3.2.1.8 * cordyceps sp. 277.0 78.5 4 PMID:25784958 -3.2.1.8 * cryptococcus sp. (in: basidiomycete fungi) 87.5 87.5 1 PMID:8987553 -3.2.1.8 * cutaneotrichosporon cutaneum 37.3 37.3 1 * -3.2.1.8 * demequina sp. jk4 8.9 6.300000000000001 2 PMID:19884762 -3.2.1.8 * dothideomycetes sp. 3126.0 2819.0 4 PMID:25784958 -3.2.1.8 * epicoccum sp. 4027.0 3253.0 4 PMID:25784958 -3.2.1.8 * euphausia superba 6820.0 5800.0 2 PMID:11126763 -3.2.1.8 * exophiala sp. 3264.0 1368.5 8 PMID:25784958 -3.2.1.8 * fusarium commune 900.0 139.0 4 PMID:26002499 -3.2.1.8 * fusarium oxysporum 37.0 37.0 1 * -3.2.1.8 * fusarium proliferatum 591.0 591.0 1 * -3.2.1.8 * fusarium sp. 1484.0 544.0 18 PMID:25784958 -3.2.1.8 * geobacillus stearothermophilus 40.58 40.58 1 PMID:16919348 -3.2.1.8 * halalkalibacterium halodurans 375.0 19.8 7 PMID:22806794;PMID:25553569 -3.2.1.8 * hordeum vulgare 7.5 7.5 1 PMID:24232655 -3.2.1.8 * irpex lacteus 11.94 10.094999999999999 2 PMID:4093442 -3.2.1.8 * laetiporus sulphureus 72.4 38.650000000000006 2 PMID:19147106 -3.2.1.8 * lentinula edodes 90.38 47.915 2 PMID:18092465 -3.2.1.8 * luteimicrobium xylanilyticum 254.0 254.0 1 PMID:28813686 -3.2.1.8 * malbranchea cinnamomea 1478.0 1028.0 3 PMID:25058752 -3.2.1.8 * malbranchea pulchella 1582.0 1528.5 2 * -3.2.1.8 * melanocarpus albomyces 200.0 36.58 9 PMID:10923787 -3.2.1.8 * melioribacter roseus 1920.0 65.0 6 PMID:25951846 -3.2.1.8 * microbacterium trichothecenolyticum 97.0 79.0 4 PMID:24861346 -3.2.1.8 * microdochium sp. 192.0 81.5 4 PMID:25784958 -3.2.1.8 * minimidochium sp. tms-2011 367.0 20.5 4 PMID:25784958 -3.2.1.8 * mycothermus thermophilus 3869.0 3869.0 1 * -3.2.1.8 * neocallimastix patriciarum 1983.0 1983.0 1 PMID:18415096 -3.2.1.8 * neurospora crassa 2621.0 1856.5 4 PMID:25784958 -3.2.1.8 * niallia circulans 37.22 18.6535 2 * -3.2.1.8 * nigrospora sp. 123.0 13.0 3 PMID:25784958 -3.2.1.8 * paecilomyces sp. 'thermophila' 706.1 706.1 1 PMID:19759868 -3.2.1.8 * paenibacillus campinasensis 2392.0 2392.0 1 * -3.2.1.8 * paenibacillus curdlanolyticus 1487.0 2.56 9 PMID:19349753;PMID:27663030;PMID:27871388 -3.2.1.8 * paenibacillus sp. 454.0 130.4 3 PMID:18391461;PMID:25112314 -3.2.1.8 * paenibacillus sp. e18 61.57 60.585 2 PMID:20382811 -3.2.1.8 * parageobacillus thermantarcticus 141.0 141.0 1 PMID:15142626 -3.2.1.8 * pediococcus acidilactici 318.45 318.45 1 PMID:30753879 -3.2.1.8 * penicillium citrinum 695.2 186.3 6 PMID:16473771;PMID:17257262;PMID:18499053;PMID:30923012 -3.2.1.8 * penicillium griseofulvum 1100.0 1100.0 1 PMID:18384043 -3.2.1.8 * penicillium occitanis (nom. inval.) 358.0 358.0 1 * -3.2.1.8 * penicillium oxalicum 150.0 72.6 3 PMID:24818699 -3.2.1.8 * penicillium sclerotiorum 249.1 245.0 2 PMID:19680819 -3.2.1.8 * penicillium sp. 2117.0 1508.0 4 PMID:25784958 -3.2.1.8 * penicillium sp. cgmcc 1669 7988.0 7988.0 1 PMID:19626289 -3.2.1.8 * phanerodontia chrysosporium 1232.0 214.5 4 PMID:25784958 -3.2.1.8 * phialophora sp. cgmcc 3328 350.6 278.9 2 PMID:21120468 -3.2.1.8 * phlebia radiata 49.99 40.370000000000005 2 PMID:11720306 -3.2.1.8 * phoma sp. 1088.0 667.5 8 PMID:25784958 -3.2.1.8 * pomacea maculata 391.8 26.4 6 PMID:18989576 -3.2.1.8 * priestia megaterium 25.6 25.6 1 PMID:9301068 -3.2.1.8 * pseudobutyrivibrio xylanivorans 14.5 14.5 1 * -3.2.1.8 * pseudopedobacter saltans 59.7 25.4 9 * -3.2.1.8 * pseudozyma hubeiensis 710.0 558.5 2 PMID:19692229 -3.2.1.8 * rasamsonia emersonii 287.5 47.75 6 * -3.2.1.8 * remersonia thermophila 20.5 20.5 1 PMID:24258792 -3.2.1.8 * rhizomucor miehei 1849.0 1849.0 1 PMID:21388922 -3.2.1.8 * rhodonia placenta 1902.0 343.5 4 PMID:25784958 -3.2.1.8 * ruminococcus flavefaciens 260.0 260.0 1 * -3.2.1.8 * saccharolobus solfataricus 11.4 6.25 2 PMID:15064978 -3.2.1.8 * schizophyllum commune 5768.0 3042.0 2 PMID:23410928 -3.2.1.8 * sphingobacterium sp. tn19 196.9 196.9 1 PMID:19554324 -3.2.1.8 * sporothrix sp. 152.0 27.0 4 PMID:25784958 -3.2.1.8 * streptomyces coelicolor 28940.0 28940.0 1 PMID:27146990 -3.2.1.8 * streptomyces cyaneus 893.6 893.6 1 PMID:17408951 -3.2.1.8 * streptomyces fradiae 304.2 174.95 2 PMID:18388456 -3.2.1.8 * streptomyces griseorubens 434.0 434.0 1 PMID:28919250 -3.2.1.8 * streptomyces ipomoeae 601.32 399.535 2 PMID:30999191 -3.2.1.8 * streptomyces olivaceoviridis 801.0 801.0 1 PMID:20361933 -3.2.1.8 * streptomyces olivaceus 153.0 153.0 1 PMID:27693622 -3.2.1.8 * streptomyces sp. 5700.0 117.4 8 PMID:10689075;PMID:14594403;PMID:22544563;PMID:24197520 -3.2.1.8 * streptomyces sp. s27 3272.0 1265.0 4 PMID:19002659;PMID:19107475 -3.2.1.8 * streptomyces sp. s9 453.7 258.65 2 PMID:18521591 -3.2.1.8 * streptomyces sp. tn119 57.9 37.15 2 PMID:19412576 -3.2.1.8 * streptomyces thermocarboxydus 70.3 70.3 1 * -3.2.1.8 * talaromyces funiculosus 115.9 50.4 3 PMID:21466666 -3.2.1.8 * talaromyces pinophilus 3991.0 112.1 5 PMID:24211645;PMID:27410423 -3.2.1.8 * talaromyces purpureogenus 47.6 47.6 1 PMID:29938332 -3.2.1.8 * termitomyces clypeatus 6917.0 3486.25 2 PMID:19728166;PMID:7189122 -3.2.1.8 * thermoascus aurantiacus 1284.0 42.4 3 PMID:2508562;PMID:27554938 -3.2.1.8 * thermoascus aurantiacus var. levisporus 2560.0 1710.5 2 * -3.2.1.8 * thermobifida fusca 686.0 536.5 4 PMID:18292971;PMID:20361933;PMID:25887328 -3.2.1.8 * thermochaetoides thermophila 125.0 35.35 4 PMID:19356131;PMID:29842954 -3.2.1.8 * thermomonospora sp. 455.0 455.0 1 PMID:11263969 -3.2.1.8 * thermomyces dupontii 160.0 160.0 1 PMID:18668373 -3.2.1.8 * thermomyces lanuginosus 15501.0 2434.5 4 PMID:10467122;PMID:9648252 -3.2.1.8 * thermothelomyces heterothallicus 875.0 1.9 5 PMID:12932372;PMID:23241981 -3.2.1.8 * thermothelomyces thermophilus 1533.7 708.25 4 PMID:23241981;PMID:29491860 -3.2.1.8 * thermothielavioides terrestris 2500.0 1334.8 2 PMID:27900528 -3.2.1.8 * thermotoga maritima 1099.0 164.0 7 * -3.2.1.8 * thermotoga petrophila 2600.0 2600.0 1 PMID:22322560 -3.2.1.8 * trichoderma harzianum 2400.0 2400.0 1 PMID:18576588 -3.2.1.8 * trichoderma inhamatum 20.34 0.35 7 PMID:18607546 -3.2.1.8 * trichoderma longibrachiatum 6630.0 6630.0 1 * -3.2.1.8 * trichoderma reesei 2873.0 1460.0 9 PMID:19556747;PMID:23241981;PMID:25784958;PMID:27138202 -3.2.1.8 * trichoderma sp. 2974.0 1396.5 16 PMID:25784958 -3.2.1.8 * uncultured bacterium 664.7 664.7 1 PMID:26358761 -3.2.1.8 * uncultured microorganism 938.0 65.25 10 PMID:21455595;PMID:23117673 -3.2.1.80 * alternaria alternata 80700.0 80700.0 1 PMID:12974403 -3.2.1.80 * arctium lappa 73.4 37.5825 2 PMID:21463533 -3.2.1.80 * asparagus officinalis 25.9 20.45 2 PMID:29931209 -3.2.1.80 * aspergillus ficuum 12300.0 12300.0 1 PMID:19127444 -3.2.1.80 * aspergillus niger 156.0 156.0 1 PMID:15135402 -3.2.1.80 * kluyveromyces marxianus 413.0 49.5 3 PMID:18051293;PMID:21067917 -3.2.1.80 * lactiplantibacillus pentosus 261.0 261.0 1 PMID:12086179 -3.2.1.80 * papiliotrema aurea 0.2 0.2 1 PMID:18456943 -3.2.1.80 * penicillium sp. 743.0 160.5 6 PMID:12400688;PMID:17502268 -3.2.1.80 * triticum aestivum 26.6 14.125 4 PMID:12586886;PMID:16330524 -3.2.1.81 * agarivorans albus 242.2 25.5 3 PMID:18071641;PMID:19349750 -3.2.1.81 * agarivorans sp. 371.0 187.55 4 PMID:15307821;PMID:17028783;PMID:23221532 -3.2.1.81 * agarivorans sp. hz105 76.8 57.45 3 PMID:19054239 -3.2.1.81 * alteromonas sp. 234.0 83.5 5 PMID:16232496;PMID:16317543;PMID:16348832 -3.2.1.81 * bacillus sp. (in: firmicutes) 14.2 14.2 1 PMID:16233415 -3.2.1.81 * cellvibrio sp. 84.2 42.45 2 PMID:21030821 -3.2.1.81 * microbulbifer sp. 517.3 4.22 3 PMID:15088129 -3.2.1.81 * microbulbifer sp. bn3 6447.0 3842.0 2 PMID:30107160 -3.2.1.81 * pseudoalteromonas antarctica 290.0 290.0 1 PMID:9797294 -3.2.1.81 * pseudoalteromonas sp. ag4 207.5 205.95 2 PMID:20213114 -3.2.1.81 * pseudoalteromonas sp. cy24 5000.0 1600.0 3 PMID:17166842;PMID:19504047 -3.2.1.81 * pseudoalteromonas sp. nj21 373.62 373.62 1 PMID:26413048 -3.2.1.81 * pseudomonas sp. 43.3 43.3 1 * -3.2.1.81 * streptomyces coelicolor 7142.0 3879.0 2 PMID:3443853;PMID:9335178 -3.2.1.81 * vibrio harveyi 22.0 22.0 1 * -3.2.1.81 * vibrio sp. 329.0 40.0 6 PMID:16957270;PMID:17213669;PMID:17340109;PMID:18478285 -3.2.1.81 * zobellia galactanivorans 0.16 0.13 2 PMID:15456406 -3.2.1.82 * aspergillus niger 418.6 186.6 3 PMID:18500582 -3.2.1.82 * bacillus pumilus 301.93 301.93 1 PMID:32871119 -3.2.1.82 * bacillus sp. (in: firmicutes) 33.1 33.1 1 PMID:11750764 -3.2.1.82 * trametes sanguinea 500.0 500.0 1 PMID:19781642 -3.2.1.83 * cellulophaga lytica 1170.0 1170.0 1 PMID:24351836 -3.2.1.83 * cytophaga sp. 6.0 6.0 1 PMID:3696007 -3.2.1.83 * microbulbifer elongatus 426.2 426.2 1 * -3.2.1.83 * pedobacter hainanensis 700.5 700.5 1 PMID:24606162 -3.2.1.83 * pseudoalteromonas porphyrae 4040.0 2029.9 2 * -3.2.1.83 * pseudoalteromonas sp. 5778.0 2919.5 2 * -3.2.1.83 * pseudoalteromonas tetraodonis 8.16 8.16 1 PMID:22451392 -3.2.1.83 * tamlana sp. 6.192 3.1347 2 * -3.2.1.84 * paenibacillus sp. 5.6 5.6 1 PMID:18326674 -3.2.1.84 * trichoderma harzianum 115.6 1.72 3 PMID:18667864;PMID:23520578 -3.2.1.84 * trichoderma sp. 11.0 11.0 1 * -3.2.1.85 * klebsiella sp. 0.032 0.018000000000000002 2 PMID:110764 -3.2.1.85 * lacticaseibacillus casei 28.9 14.59 2 PMID:5057373 -3.2.1.85 * lactococcus cremoris 23.8 23.8 1 PMID:4204438 -3.2.1.85 * lactococcus lactis 2.44 1.45 3 PMID:3086494;PMID:3130294 -3.2.1.85 * leptotrichia buccalis 21.6 21.6 1 PMID:12351228 -3.2.1.85 * staphylococcus aureus 100.0 69.0 2 PMID:1409548;PMID:237202;PMID:5447434 -3.2.1.85 * streptococcus mutans 20.9 20.9 1 PMID:33899 -3.2.1.86 * escherichia coli 85.0 85.0 1 PMID:4607165 -3.2.1.86 * klebsiella aerogenes 0.54 0.54 1 PMID:237203;PMID:4624114 -3.2.1.86 * pectobacterium carotovorum 565.0 565.0 1 PMID:15748978 -3.2.1.86 * streptococcus pneumoniae 3.37 3.37 1 PMID:26527213 -3.2.1.87 * klebsiella aerogenes 235.0 235.0 1 PMID:5096084 -3.2.1.89 * aspergillus aculeatus 3060.0 3059.5 2 * -3.2.1.89 * aspergillus niger 6593.0 3302.65 2 PMID:12383257;PMID:8520117 -3.2.1.89 * aspergillus sojae 660.0 660.0 1 * -3.2.1.89 * bacillus subtilis 1790.0 182.5 6 PMID:823153 -3.2.1.89 * bacillus subtilis subsp. subtilis 3110.79 2485.125 2 PMID:36280173 -3.2.1.89 * penicillium chrysogenum 7.6 7.6 1 PMID:22584433 -3.2.1.89 * penicillium citrinum 238.0 231.0 2 * -3.2.1.89 * thermotoga maritima 21.8 21.8 1 PMID:16495677 -3.2.1.91 * acetivibrio thermocellus 24.6 18.0 7 PMID:8507185 -3.2.1.91 * aspergillus nidulans 41.0 33.5 2 PMID:23076365 -3.2.1.91 * aspergillus niger 2.9 2.9 1 * -3.2.1.91 * cellulomonas uda 0.0571 0.0571 1 * -3.2.1.91 * fibrobacter succinogenes 11.93 11.93 1 PMID:3384799 -3.2.1.91 * fomitopsis pinicola 26.0 15.0 2 PMID:21193824 -3.2.1.91 * irpex lacteus 26.0 24.45 4 * -3.2.1.91 * neocallimastix patriciarum 1809.0 58.35 6 PMID:23770555 -3.2.1.91 * niallia circulans 14.26 14.26 1 * -3.2.1.91 * phanerodontia chrysosporium 2.15 1.875 2 * -3.2.1.91 * rasamsonia emersonii 16.5 16.5 1 PMID:12007616 -3.2.1.91 * talaromyces purpureogenus 10.8 6.7 2 PMID:20582640 -3.2.1.91 * thermoclostridium stercorarium 0.037 0.037 1 PMID:1909625 -3.2.1.91 * thermothelomyces heterothallicus 0.32 0.32 1 * -3.2.1.91 * thermothelomyces thermophilus 0.32 0.32 1 * -3.2.1.91 * thermotoga petrophila 66.5 66.5 1 PMID:30406735 -3.2.1.91 * thermotoga sp. 4.9 4.9 1 PMID:1872819 -3.2.1.91 * trichoderma harzianum 6.67 6.67 1 * -3.2.1.91 * trichoderma reesei 2.4 2.06 2 PMID:22638966 -3.2.1.91 * trichoderma virens 4.195 2.3525 2 PMID:30261309 -3.2.1.92 * bacillus subtilis 24.2 24.2 1 PMID:6281 -3.2.1.93 * paenibacillus popilliae 2.83 2.83 1 PMID:4369400 -3.2.1.94 * actinomadura sp. 5.0 5.0 1 * -3.2.1.94 * arthrobacter dextranolyticus 43.0 43.0 1 PMID:15248038 -3.2.1.94 * arthrobacter globiformis 18.8 15.3 3 PMID:15200177;PMID:4826536 -3.2.1.95 * brevibacterium fuscum 21.5 21.5 1 PMID:10540747 -3.2.1.96 * bacillus sp. (in: firmicutes) 0.0216 0.0114 2 * -3.2.1.96 * clostridium perfringens 0.304 0.3015 2 PMID:242275 -3.2.1.96 * flavobacterium sp. 39.9 39.9 1 * -3.2.1.96 * gallus gallus 0.24 0.24 1 PMID:9498561 -3.2.1.96 * glutamicibacter protophormiae 1.72 1.72 1 PMID:19252736 -3.2.1.96 * homo sapiens 2.3 2.3 1 PMID:12114544 -3.2.1.96 * lathyrus oleraceus 400.0 400.0 1 PMID:9063968 -3.2.1.96 * mucor hiemalis 9.5 1.6 3 PMID:18096701;PMID:19880511 -3.2.1.96 * streptococcus pneumoniae 13.4 9.035 2 PMID:26846;PMID:4152561;PMID:75885 -3.2.1.96 * streptomyces griseus 12.0 6.376 2 PMID:4154323;PMID:4204552 -3.2.1.97 * alcaligenes sp. 2.18 2.18 1 * -3.2.1.97 * bacillus sp. (in: firmicutes) 30.1 30.1 1 PMID:10620364 -3.2.1.97 * streptococcus pneumoniae 11.5 11.5 1 PMID:26847 -3.2.1.98 * bacillus sp. (in: firmicutes) 18.8 1.5 3 PMID:15518553 -3.2.1.98 * bacillus sp. h-167 147.0 124.0 3 * -3.2.1.98 * klebsiella pneumoniae 18.4 15.6 3 PMID:1094;PMID:18548722 -3.2.1.99 * aspergillus niger 90.2 14.0 5 * -3.2.1.99 * bacillus licheniformis 71.69 64.52 6 PMID:23274993 -3.2.1.99 * bacillus subtilis 429.0 48.8 7 PMID:1096;PMID:15556708;PMID:16660741 -3.2.1.99 * caldicellulosiruptor saccharolyticus dsm 8903 12.0 7.3 2 PMID:19458916 -3.2.1.99 * chrysosporium lucknowense 26.0 26.0 1 PMID:20933404 -3.2.1.99 * geobacillus thermodenitrificans 445.0 432.5 2 PMID:11916679;PMID:11999422 -3.2.1.99 * paenibacillus polymyxa 73.4 73.4 1 PMID:25077565 -3.2.1.99 * pseudothermotoga thermarum 237.7 199.7 3 PMID:24886412 -3.2.1.99 * rhizomucor miehei 109.0 109.0 1 PMID:25582414 -3.2.1.99 * thermotoga petrophila 152.1 152.1 1 PMID:20678476 -3.2.2.1 * aspergillus niger 55.0 29.5 2 PMID:208724 -3.2.2.1 * bacillus thuringiensis 57.2 11.76 3 PMID:18451042 -3.2.2.1 * brucella anthropi 90.3 90.3 1 PMID:11282633 -3.2.2.1 * crithidia fasciculata 0.047 0.047 1 PMID:1939115 -3.2.2.1 * lentilactobacillus buchneri 0.671 0.671 1 PMID:27180876 -3.2.2.1 * salmonella enterica 11.3 11.3 1 PMID:15784179 -3.2.2.1 * trypanosoma brucei 50.0 50.0 1 PMID:8702965 -3.2.2.1 * vigna unguiculata 0.432 0.432 1 * -3.2.2.10 * streptomyces virginiae 2.5 2.5 1 * -3.2.2.14 * azotobacter vinelandii 0.0195 0.0195 1 PMID:457634 -3.2.2.14 * escherichia coli 0.07 0.0069 3 PMID:4342726;PMID:457634 -3.2.2.14 * salmonella enterica subsp. enterica serovar typhimurium 0.478 0.176 17 PMID:6109709 -3.2.2.16 * arabidopsis thaliana 11.05 1.915 16 PMID:18342331 -3.2.2.16 * borreliella burgdorferi 4.4 4.25 2 PMID:19376840 -3.2.2.16 * escherichia coli 373.0 186.519 2 PMID:3911944 -3.2.2.16 * glycine max 16.88 16.88 3 * -3.2.2.16 * homo sapiens 2.75 2.75 1 PMID:631411 -3.2.2.16 * lupinus luteus 27.0 27.0 1 PMID:6783408 -3.2.2.16 * oryza sativa 3.84 2.35 11 PMID:17339651 -3.2.2.19 * meleagris gallopavo 4.87e-05 4.76e-05 3 PMID:3179279;PMID:3778868 -3.2.2.19 * rattus norvegicus 3.15 0.00046 13 PMID:10358013;PMID:1375222;PMID:8678289;PMID:9037477 -3.2.2.2 * arabidopsis thaliana 14.5 14.5 1 PMID:19293370 -3.2.2.2 * azotobacter vinelandii 2.33 2.33 1 PMID:31149 -3.2.2.2 * bacillus thuringiensis 57.2 11.76 3 PMID:18451042 -3.2.2.2 * lupinus luteus 9.25 4.626375 2 PMID:16662492;PMID:16820181 -3.2.2.20 * escherichia coli 0.0093 0.0083 2 PMID:352392;PMID:3550703 -3.2.2.20 * micrococcus luteus 0.000242 0.000242 1 PMID:3628000 -3.2.2.21 * escherichia coli 0.0247 0.0247 1 PMID:7982966 -3.2.2.21 * micrococcus luteus 0.000375 0.000375 1 PMID:3628000 -3.2.2.21 * mus musculus 1.4e-05 1.4e-05 1 PMID:10660595 -3.2.2.22 * sambucus nigra 1.4e-05 1.2499999999999999e-05 2 PMID:15066176 -3.2.2.23 * escherichia coli 0.5 0.04815 4 PMID:2664776;PMID:3319582;PMID:9125531 -3.2.2.24 * rhodospirillum rubrum 138.0 48.35 4 PMID:7836296;PMID:7945205 -3.2.2.25 * camellia sinensis 0.0294 0.01798 2 * -3.2.2.27 * archaeoglobus fulgidus 0.009 0.009 1 PMID:11738943 -3.2.2.27 * deinococcus radiodurans 0.01 0.01 1 PMID:16223719 -3.2.2.27 * gadus morhua 379.0 379.0 1 PMID:11126771 -3.2.2.27 * murid gammaherpesvirus 4 21.8 3.35 8 PMID:37315375 -3.2.2.27 * mus musculus 36.2 3.0 8 PMID:37315375 -3.2.2.27 * mycolicibacterium smegmatis 14000.0 14000.0 1 PMID:9780234 -3.2.2.27 * pyrobaculum islandicum 1.23 1.2 3 PMID:8837481 -3.2.2.27 * pyrococcus furiosus 1.67 1.33 3 PMID:8837481 -3.2.2.27 * saccharolobus shibatae 2.9 2.67 3 PMID:8837481 -3.2.2.27 * saccharolobus solfataricus 11.9 11.1 3 PMID:8837481 -3.2.2.27 * thermotoga maritima 14.7 13.7 3 PMID:8837481 -3.2.2.3 * arabidopsis thaliana 303.3 303.3 1 PMID:19293370 -3.2.2.3 * hordeum vulgare 0.77 0.77 1 * -3.2.2.3 * saccharomyces cerevisiae 1.56 1.56 1 PMID:237897;PMID:357896 -3.2.2.3 * vigna radiata var. radiata 0.725 0.725 1 PMID:6052429 -3.2.2.3 * zea mays 21.64 21.64 1 PMID:38044809 -3.2.2.30 * arabidopsis thaliana 6.25 1.5 7 PMID:18342331 -3.2.2.4 * azotobacter beijerinckii 0.04 0.04 1 * -3.2.2.4 * azotobacter vinelandii 8000.0 21.0 6 PMID:2690948;PMID:3485632;PMID:357895;PMID:5041898;PMID:5118623;PMID:6251048;PMID:6378909;PMID:931993 -3.2.2.4 * escherichia coli 47.0 20.5 6 PMID:3533942;PMID:357895;PMID:6327703;PMID:6378909;PMID:7000783 -3.2.2.5 * aplysia californica 126.0 126.0 1 PMID:1650254 -3.2.2.5 * bacillus subtilis 850.0 850.0 1 PMID:6246385 -3.2.2.5 * bos taurus 9900.0 128.8 8 PMID:2986595;PMID:6246386;PMID:6279;PMID:8391778;PMID:8549791 -3.2.2.5 * bungarus fasciatus 1320.0 661.85 2 PMID:3010034;PMID:6486411 -3.2.2.5 * deinagkistrodon acutus 12.8 11.850000000000001 2 PMID:12135566;PMID:2845606 -3.2.2.5 * microdochium nivale 996.0 996.0 1 PMID:4144238 -3.2.2.5 * neurospora crassa 51.0 51.0 1 PMID:6260480 -3.2.2.5 * oryctolagus cuniculus 74.5 74.5 1 PMID:24759100 -3.2.2.5 * rattus norvegicus 1316.0 511.0 3 PMID:31183;PMID:6870260 -3.2.2.5 * streptococcus pyogenes 11.2 11.2 1 PMID:236282 -3.2.2.5 * sus scrofa 7600.0 7600.0 1 * -3.2.2.6 * homo sapiens 2.205 0.113 3 PMID:10825668 -3.2.2.6 * saccharomyces cerevisiae 662.0 535.5 2 * -3.2.2.6 * xenopus laevis 0.0604 0.0604 1 PMID:22422046 -3.2.2.7 * brassica oleracea 0.62 0.62 1 PMID:14085386 -3.2.2.7 * camellia sinensis 12.84 7.484999999999999 4 * -3.2.2.7 * coffea arabica 500.0 500.0 1 PMID:15652571 -3.2.2.7 * hordeum vulgare 30.5 10.0 3 PMID:861230 -3.2.2.7 * lathyrus oleraceus 0.308 0.308 1 PMID:30366031 -3.2.2.7 * lupinus luteus 6.6 0.049 3 PMID:24414266 -3.2.2.7 * solanum tuberosum 10.6 10.6 1 * -3.2.2.7 * triticum aestivum 0.74 0.74 1 PMID:16662043 -3.2.2.8 * arabidopsis thaliana 14.5 14.5 1 PMID:19293370 -3.2.2.8 * leishmania donovani 8.5 8.5 1 PMID:468819 -3.2.2.8 * pseudomonas fluorescens 272.0 272.0 1 PMID:12325375 -3.2.2.9 * arabidopsis thaliana 0.9 0.9 1 PMID:18342331 -3.2.2.9 * borreliella burgdorferi 3.7 3.4000000000000004 2 PMID:19376840 -3.2.2.9 * escherichia coli 373.0 9.93 7 PMID:3911944;PMID:782530 -3.3.2.10 * arabidopsis thaliana 3.9 3.9 1 PMID:10860549 -3.3.2.10 * aspergillus niger 0.102 0.102 1 PMID:10406946 -3.3.2.10 * cavia porcellus 0.00264 0.001565 2 PMID:7361100 -3.3.2.10 * corynebacterium sp. 1.41 1.41 1 PMID:9578475 -3.3.2.10 * cress 3.91 3.91 1 PMID:10860549 -3.3.2.10 * gallus gallus 0.823 0.018500000000000003 4 PMID:16523628 -3.3.2.10 * homo sapiens 67.64 0.2525 32 PMID:12574510;PMID:14665429;PMID:15963942;PMID:19782755;PMID:30218745;PMID:3169021;PMID:34066758;PMID:6185139 -3.3.2.10 * mus musculus 1.5 0.427 16 PMID:15963942;PMID:1910279;PMID:3369689;PMID:3856846;PMID:3996389;PMID:6847673;PMID:7361100 -3.3.2.10 * oryctolagus cuniculus 1.38 1.38 1 PMID:7117244 -3.3.2.10 * rattus norvegicus 0.173 0.0012850000000000001 6 PMID:14737000;PMID:3046942;PMID:7361100 -3.3.2.10 * solanum tuberosum 2.67 0.063 3 PMID:10860549;PMID:7920715 -3.3.2.10 * strongylocentrotus purpuratus 4.8 1.795 6 PMID:18554159 -3.3.2.11 * homo sapiens 0.00108 0.00073 2 PMID:4026314 -3.3.2.11 * mesocricetus auratus 0.0002 0.00015000000000000001 2 PMID:4026314 -3.3.2.11 * mus musculus 0.00051 0.00033 3 PMID:3778472;PMID:4026314 -3.3.2.11 * oryctolagus cuniculus 0.00014 8.999999999999999e-05 2 PMID:4026314 -3.3.2.11 * rattus norvegicus 0.00123 0.0005 10 PMID:3606651;PMID:3730418;PMID:3941086;PMID:4026314;PMID:6401984 -3.3.2.12 * escherichia coli 0.02 0.02 1 PMID:20660314 -3.3.2.14 * nocardioides sp. 6.4 6.4 1 PMID:25281383 -3.3.2.2 * legionella pneumophila 8.443 4.249 2 PMID:25445671 -3.3.2.2 * rattus norvegicus 15.76 0.0955 4 PMID:10064898;PMID:21515882;PMID:2764893 -3.3.2.2 * thermocrispum sp. rd004668 345.0 315.0 2 PMID:27833852;PMID:33599379 -3.3.2.4 * pseudomonas putida 229.0 229.0 1 PMID:5782001 -3.3.2.6 * cavia porcellus 1.8 1.165 2 PMID:2722767;PMID:3391178 -3.3.2.6 * homo sapiens 2.0 1.11 2 PMID:2172732;PMID:3038871 -3.3.2.6 * mus musculus 0.185 0.185 1 PMID:1932096 -3.3.2.6 * xenopus laevis 6.7 6.7 1 PMID:9744798 -3.3.2.8 * rhodococcus erythropolis 85.1 6.18 5 * -3.3.2.8 * uncultured organism 1.33 0.1935 4 * -3.3.2.9 * canis lupus familiaris 1.98 1.98 1 PMID:7961616 -3.3.2.9 * cavia porcellus 0.842 0.0036 3 PMID:4998715;PMID:7361100 -3.3.2.9 * danio rerio 11.4 11.4 1 * -3.3.2.9 * heliothis virescens 1.18 0.02475 10 PMID:23276675 -3.3.2.9 * homalodisca vitripennis 0.0475 0.0153 4 PMID:23704009 -3.3.2.9 * homo sapiens 0.618 0.0272 15 PMID:109443;PMID:21371418;PMID:3384870;PMID:34066758;PMID:4075436;PMID:4463951 -3.3.2.9 * manduca sexta 0.659 0.0083 3 PMID:8396141;PMID:9692241 -3.3.2.9 * mus musculus 0.0064 0.00019 3 PMID:3778472;PMID:7361100 -3.3.2.9 * rattus norvegicus 524.0 0.051949999999999996 16 PMID:1227945;PMID:14737000;PMID:21371418;PMID:3082328;PMID:3384870;PMID:672628;PMID:7329313;PMID:7361100;PMID:8383521;PMID:869931 -3.3.2.9 * rhodotorula glutinis 0.196 0.196 1 PMID:11166814 -3.3.2.9 * tribolium castaneum 0.093 0.04785 2 PMID:20337748 -3.4.11.1 * acinetobacter calcoaceticus 268.1 268.1 1 PMID:8229672 -3.4.11.1 * aspergillus oryzae 262.3 142.0 7 PMID:20803144 -3.4.11.1 * bacillus cereus 1426.0 1426.0 1 PMID:37958921 -3.4.11.1 * bacillus subtilis 240.48 186.49 2 PMID:25389014 -3.4.11.1 * bos taurus 10.9 5.825 2 PMID:14583094;PMID:8725056 -3.4.11.1 * cannabis sativa 0.18 0.18 1 PMID:10879480 -3.4.11.1 * desulfurococcus amylolyticus 4.1 4.1 1 PMID:22419090 -3.4.11.1 * eisenia fetida 0.958 0.958 1 * -3.4.11.1 * escherichia coli 790.5 355.1 9 PMID:10672029 -3.4.11.1 * fasciola hepatica 4.27 4.27 1 PMID:9488329 -3.4.11.1 * geobacillus kaustophilus 160.0 160.0 1 PMID:18848841 -3.4.11.1 * homo sapiens 58.0 4.4 3 PMID:11056387;PMID:1931152;PMID:3733731 -3.4.11.1 * lactobacillus acidophilus 4.2 4.2 1 PMID:6432050 -3.4.11.1 * lingulaulax polyedra 60.0 60.0 1 PMID:10462513 -3.4.11.1 * magallana gigas 0.012 0.012 1 PMID:14602147 -3.4.11.1 * morimus funereus 1108.0 1108.0 1 PMID:18155948 -3.4.11.1 * pagrus major 3977.0 1988.9 2 PMID:18800800 -3.4.11.1 * phaseolus vulgaris 171.0 171.0 1 * -3.4.11.1 * pseudomonas aeruginosa 155.4 86.88 2 PMID:9151424 -3.4.11.1 * rattus norvegicus 52.0 1.1 7 PMID:12675513 -3.4.11.1 * salmonella enterica 550.0 126.0 15 PMID:10852868 -3.4.11.1 * schistosoma mansoni 16.52 16.52 1 PMID:2298275 -3.4.11.1 * schizosaccharomyces pombe 196.9 196.9 1 PMID:18028193 -3.4.11.1 * setaria cervi 18.2 18.2 1 PMID:18262499 -3.4.11.1 * solanum lycopersicum 440.9 146.0 28 PMID:10469136;PMID:10672029;PMID:11895433 -3.4.11.1 * streptomyces rimosus 156.0 156.0 1 * -3.4.11.1 * sus scrofa 260.0 9.0 18 PMID:10672029;PMID:19433052;PMID:21396812;PMID:3922244 -3.4.11.1 * thermomyces lanuginosus 7449.6 7449.6 2 PMID:31759085;PMID:36625962 -3.4.11.1 * thermotoga maritima 16.5 16.5 1 * -3.4.11.10 * aeromonas caviae 55.0 55.0 1 * -3.4.11.10 * bacillus subtilis 240.48 186.49 4 PMID:15668014;PMID:25389014;PMID:36625962 -3.4.11.10 * borreliella burgdorferi 0.001 0.001 1 PMID:15784569 -3.4.11.10 * escherichia coli 105.0 6.235 12 PMID:20350528;PMID:4920230 -3.4.11.10 * fasciola hepatica 0.2145 0.0066 30 PMID:18178266 -3.4.11.10 * geobacillus kaustophilus 91.6 91.6 1 PMID:15702388 -3.4.11.10 * geobacillus stearothermophilus 572.5 60.73 9 PMID:15928987;PMID:18286359;PMID:20373125 -3.4.11.10 * streptomyces septatus 68.0 68.0 1 PMID:17028223 -3.4.11.10 * vibrio proteolyticus 120.0 35.5 13 PMID:1012016;PMID:11401547;PMID:1550363;PMID:19233285;PMID:4831337;PMID:4961737;PMID:5102149;PMID:7173208 -3.4.11.13 * hathewaya histolytica 317.0 163.75 2 PMID:13266;PMID:36625962;PMID:4318;PMID:4631895 -3.4.11.14 * acinetobacter calcoaceticus 281.7 281.7 1 PMID:8229672 -3.4.11.14 * homo sapiens 76.7 70.0 3 PMID:1148200;PMID:4841062;PMID:698181 -3.4.11.15 * pyrococcus furiosus 1900.0 1900.0 3 PMID:15743956;PMID:36625962 -3.4.11.15 * saccharomyces cerevisiae 43.32 0.2 3 PMID:6758786;PMID:8175799 -3.4.11.16 * sus scrofa 68050.0 34031.5 2 PMID:4062876 -3.4.11.17 * cutaneotrichosporon cutaneum 1110.0 1110.0 1 * -3.4.11.18 * bacillus subtilis 232.0 21.8 4 PMID:16207374 -3.4.11.18 * encephalitozoon cuniculi 11.7 7.9 3 PMID:19660503 -3.4.11.18 * escherichia coli 11.3 11.3 1 PMID:3027045 -3.4.11.18 * homo sapiens 396.0 11.65 16 PMID:15196033;PMID:19660503;PMID:24700462 -3.4.11.18 * mycolicibacterium smegmatis 16.2 8.469999999999999 2 PMID:18594775 -3.4.11.18 * plasmodium vivax 436.0 436.0 1 PMID:25595410 -3.4.11.19 * bacillus subtilis 80.0 80.0 1 PMID:11069674 -3.4.11.2 * bombyx mori 190.0 167.25 2 PMID:16452310;PMID:8063017 -3.4.11.2 * bos taurus 659.0 659.0 1 PMID:16717410 -3.4.11.2 * brucella melitensis 150.0 150.0 1 PMID:17064279 -3.4.11.2 * cavia porcellus 9.65 9.65 1 PMID:11732752 -3.4.11.2 * citrullus lanatus 0.57 0.18 11 PMID:16054196 -3.4.11.2 * cucumis sativus 6.86 6.86 1 PMID:11826983 -3.4.11.2 * escherichia coli 964.0 3.54 23 PMID:16380266;PMID:18416562;PMID:20350528;PMID:36625962 -3.4.11.2 * homo sapiens 1.38 1.38 1 PMID:11732752 -3.4.11.2 * mizuhopecten yessoensis 53.0 53.0 1 * -3.4.11.2 * novosphingobium capsulatum 105.0 105.0 1 PMID:11359790 -3.4.11.2 * oncorhynchus mykiss 0.0033 0.00245 2 PMID:16044310 -3.4.11.2 * oryctolagus cuniculus 1.67 1.67 1 PMID:11732752 -3.4.11.2 * ovis aries 13.1 13.1 1 PMID:11732752 -3.4.11.2 * rattus norvegicus 33.5 0.34454999999999997 14 PMID:11732752;PMID:14706551;PMID:16044310;PMID:6122685;PMID:931983 -3.4.11.2 * sparus aurata 0.0081 0.0062 2 PMID:16044310 -3.4.11.2 * spodoptera litura 0.006 0.006 1 PMID:17467291 -3.4.11.2 * streptococcus salivarius 5.7 4.0 3 PMID:7989254 -3.4.11.2 * streptomyces sp. 18.3 18.3 1 PMID:17082929 -3.4.11.2 * sus scrofa 29.0 16.0 2 PMID:4750768;PMID:8963385 -3.4.11.20 * gallus gallus 3083.0 3083.0 1 * -3.4.11.21 * aspergillus oryzae 0.125 0.125 1 PMID:28946286 -3.4.11.21 * homo sapiens 0.272 0.272 1 PMID:9632644 -3.4.11.21 * rattus norvegicus 0.00041 0.00024 5 PMID:14706551 -3.4.11.21 * rattus sp. 0.013 0.013 1 PMID:9632644 -3.4.11.21 * sus scrofa 0.07 0.07 1 PMID:7011318 -3.4.11.22 * aspergillus oryzae 4.12 4.12 1 PMID:10899618 -3.4.11.22 * chara australis 6.36 6.36 1 PMID:16665510 -3.4.11.22 * cryptomeria japonica 6.7 4.65 2 PMID:12033825;PMID:15969531 -3.4.11.22 * geobacillus stearothermophilus 425.0 425.0 1 PMID:12783191 -3.4.11.22 * grifola frondosa 8.55 8.55 1 PMID:11302180 -3.4.11.22 * novosphingobium capsulatum 105.0 105.0 1 PMID:11359790 -3.4.11.22 * parietaria judaica 4.88 2.52 2 PMID:17030241 -3.4.11.22 * saccharomyces cerevisiae 3000.0 980.0 3 PMID:3882418;PMID:5147 -3.4.11.23 * salmonella enterica subsp. enterica serovar typhimurium 190.0 190.0 1 PMID:10852868 -3.4.11.24 * saccharomyces cerevisiae 4.05 4.05 1 PMID:10649451 -3.4.11.24 * streptomyces griseus 830.0 543.05 6 PMID:12821322;PMID:15280041;PMID:2503378 -3.4.11.24 * streptomyces sp. 0.158 0.0063 10 * -3.4.11.24 * streptomyces thermocyaneoviolaceus 1244.0 21.765 4 PMID:20303368 -3.4.11.25 * sphingosinicella microcystinivorans 0.2 0.2 1 PMID:17064315 -3.4.11.25 * sphingosinicella xenopeptidilytica 2.4 1.51 2 PMID:16109932;PMID:17064315 -3.4.11.27 * pyrococcus horikoshii 19.87 11.175 2 PMID:25192005 -3.4.11.3 * homo sapiens 52.0 28.175 2 * -3.4.11.3 * lactobacillus helveticus 2.6 2.6 1 PMID:36625962 -3.4.11.3 * macaca fuscata fuscata 0.2087 0.2087 1 PMID:12146 -3.4.11.3 * saccharomyces cerevisiae 0.0129 0.0129 1 PMID:8482390 -3.4.11.4 * bacillus subtilis 1022.0 1022.0 1 * -3.4.11.4 * bos taurus 59.5 59.5 1 PMID:8177230 -3.4.11.4 * cavia porcellus 22.9 22.9 1 PMID:3881261 -3.4.11.4 * escherichia coli 35.0 5.800000000000001 12 PMID:20350528;PMID:356879 -3.4.11.4 * oryctolagus cuniculus 380.0 380.0 1 PMID:109082 -3.4.11.4 * pediococcus pentosaceus 1041.0 1041.0 1 PMID:9406407 -3.4.11.4 * rattus norvegicus 73.5 73.5 1 PMID:7126601 -3.4.11.5 * acinetobacter calcoaceticus 1.43 1.43 1 PMID:8229672 -3.4.11.5 * aneurinibacillus sp. 18.0 5.5 3 PMID:15012820;PMID:17142913 -3.4.11.5 * aspergillus niger 290.0 44.45 6 PMID:15654623 -3.4.11.5 * aspergillus oryzae 247.3 25.7 11 PMID:20028436;PMID:27628336;PMID:36625962 -3.4.11.5 * brassica oleracea 10.0 5.006 2 PMID:18386498 -3.4.11.5 * cutibacterium acnes 5.13 5.13 1 PMID:4082822 -3.4.11.5 * debaryomyces hansenii 1.06 1.06 1 PMID:12513999 -3.4.11.5 * kitasatospora aureofaciens 3.28 3.28 1 PMID:17916451 -3.4.11.5 * lactiplantibacillus plantarum 26.4 26.4 1 PMID:29274418 -3.4.11.5 * lyophyllum cinerascens 191.0 191.0 1 * -3.4.11.5 * penicillium camemberti 36880.0 36880.0 1 * -3.4.11.5 * secale cereale 8.5 8.5 1 * -3.4.11.5 * serratia marcescens 8.34 0.8 3 PMID:16452443 -3.4.11.5 * sus scrofa 780.0 780.0 1 PMID:4803482 -3.4.11.5 * treponema denticola 0.48 0.48 1 * -3.4.11.5 * triticum aestivum 68.3 68.3 1 PMID:16663327 -3.4.11.6 * aspergillus niger 412.7 412.7 1 PMID:34290949 -3.4.11.6 * bacillus subtilis 64.0 64.0 2 PMID:15668014;PMID:36625962 -3.4.11.6 * bos taurus 26.0 26.0 1 * -3.4.11.6 * capnocytophaga granulosa 297.9 297.9 1 PMID:15720565 -3.4.11.6 * capra aegagrus 0.06708 0.06708 1 * -3.4.11.6 * homo sapiens 6974.0 27.0 3 PMID:1823861;PMID:8143849;PMID:8940051 -3.4.11.6 * latilactobacillus sakei 1.17 1.17 1 PMID:11916721 -3.4.11.6 * mycosarcoma maydis 0.63 0.63 1 PMID:15135529 -3.4.11.6 * oncorhynchus mykiss 0.00012 0.000115 2 PMID:16044310 -3.4.11.6 * pediococcus acidilactici 133.27 133.27 1 * -3.4.11.6 * rattus norvegicus 140.0 0.1 15 PMID:14706551;PMID:16044310;PMID:17142967;PMID:8940051 -3.4.11.6 * sparus aurata 0.00082 0.000565 2 PMID:16044310 -3.4.11.6 * sus scrofa 9.9 9.9 1 PMID:7451402 -3.4.11.6 * toxoplasma gondii 263.7 97.5 4 PMID:10910719 -3.4.11.7 * acinetobacter calcoaceticus 9.88 9.88 1 PMID:8229672 -3.4.11.7 * bothrops jararaca 1.38e-05 1.38e-05 1 PMID:17383704 -3.4.11.7 * crotalus atrox 3e-06 3e-06 1 PMID:17383704 -3.4.11.7 * gallus gallus 19.76 19.76 1 PMID:2331880 -3.4.11.7 * gloydius blomhoffii 7.1e-06 7.1e-06 1 PMID:17383704 -3.4.11.7 * gloydius brevicauda 1.4e-05 1.4e-05 1 PMID:17383704 -3.4.11.7 * glycine max 319.0 132.0 3 PMID:20057138 -3.4.11.7 * homo sapiens 40.0 12.0 3 PMID:12126112;PMID:6272866 -3.4.11.7 * lactobacillus delbrueckii 234.0 234.0 1 PMID:36625962 -3.4.11.7 * lactobacillus delbrueckii subsp. lactis 78.6 14.809999999999999 6 PMID:27815133;PMID:29310858 -3.4.11.7 * lactococcus lactis 7.06 7.06 1 * -3.4.11.7 * mus musculus 54.9 1.98 13 PMID:16889841;PMID:19228697;PMID:9688281 -3.4.11.7 * oncorhynchus mykiss 6e-05 5.3e-05 2 PMID:16044310 -3.4.11.7 * plasmodium falciparum 662.5 634.75 2 PMID:17720817 -3.4.11.7 * protobothrops flavoviridis 7.1e-06 7.1e-06 1 PMID:17383704 -3.4.11.7 * rattus norvegicus 0.001557 0.000686 17 PMID:16044310;PMID:17031265;PMID:18362226 -3.4.11.7 * sparus aurata 7e-05 6.95e-05 2 PMID:16044310 -3.4.11.7 * sus scrofa 36.1 29.450000000000003 2 PMID:7011318;PMID:7448199 -3.4.11.7 * thermoplasma acidophilum 72.4 1.1 9 PMID:9845366 -3.4.11.9 * aspergillus oryzae 177.69 177.69 1 PMID:28698148 -3.4.11.9 * escherichia coli 3.45 1.83 2 PMID:2851590 -3.4.11.9 * homo sapiens 0.022 0.019 2 PMID:12086766 -3.4.11.9 * lactococcus lactis 1.343 1.343 1 PMID:9275257 -3.4.11.9 * plasmodium falciparum 1480.0 1480.0 1 PMID:27462122 -3.4.11.9 * rattus norvegicus 31.7 31.7 1 PMID:1645659 -3.4.11.9 * sus scrofa 3534.0 1767.01875 2 PMID:11106491;PMID:2139778 -3.4.13.12 * escherichia coli 1100.0 1100.0 1 PMID:4567782 -3.4.13.12 * neurospora crassa 200.0 200.0 1 PMID:4280316 -3.4.13.17 * loligo vulgaris 23.3 23.3 1 PMID:6444201 -3.4.13.18 * abramis brama 0.0346 0.0346 1 PMID:14529758 -3.4.13.18 * escherichia coli 760.0 760.0 1 PMID:13264 -3.4.13.18 * homo sapiens 3.0 3.0 1 PMID:15039077 -3.4.13.18 * perca fluviatilis 0.0346 0.0346 1 PMID:14529758 -3.4.13.18 * sander lucioperca 0.0346 0.0346 1 PMID:14529758 -3.4.13.19 * raphanus sativus 0.44 0.44 1 PMID:18071263 -3.4.13.19 * rattus norvegicus 624.0 624.0 1 PMID:6126478 -3.4.13.19 * sus scrofa 21.0 21.0 1 PMID:3619022 -3.4.13.21 * escherichia coli 3.39 3.39 1 PMID:19664550 -3.4.13.21 * salmonella enterica subsp. enterica serovar typhimurium 2.0 2.0 1 PMID:6086568 -3.4.13.21 * xenopus laevis 0.0014 0.0014 1 PMID:10762256 -3.4.13.22 * lactiplantibacillus plantarum 0.3872 0.0019 3 PMID:17400741 -3.4.13.22 * streptomyces coelicolor 10.6 10.6 1 PMID:11881895 -3.4.13.23 * rattus norvegicus 63.6 1.6 3 PMID:19061865 -3.4.13.4 * sus scrofa 0.8 0.8 1 PMID:5436646 -3.4.13.5 * katsuwonus pelamis 0.175 0.1525 2 PMID:318374;PMID:6067033 -3.4.13.5 * oncorhynchus mykiss 1.27 1.15 2 * -3.4.13.5 * oreochromis niloticus 9.27 9.27 1 PMID:16302965 -3.4.13.9 * alteromonas sp. 1950.0 1950.0 1 PMID:19426854 -3.4.13.9 * cavia porcellus 49.47 49.47 1 PMID:6853481 -3.4.13.9 * homo sapiens 21500.0 158.3 7 PMID:15169634;PMID:15902422;PMID:16122899;PMID:19415262;PMID:19426854;PMID:2713125 -3.4.13.9 * lactobacillus delbrueckii 446.0 446.0 1 PMID:10075426 -3.4.13.9 * lactococcus lactis 468.7 159.7 11 PMID:18070105;PMID:19336036 -3.4.13.9 * microbacterium esteraromaticum 243.0 243.0 1 PMID:8782407 -3.4.13.9 * neurospora crassa 217.0 217.0 1 PMID:4280316 -3.4.13.9 * oenococcus oeni 0.129 0.041 3 PMID:17320992 -3.4.13.9 * pyrococcus furiosus 1388.0 965.0 6 PMID:15005612;PMID:16243319;PMID:19426854;PMID:9733678 -3.4.13.9 * pyrococcus horikoshii 2355.0 1938.0 3 PMID:19784642;PMID:22162664 -3.4.13.9 * stenotrophomonas maltophilia 7.35 7.35 1 PMID:8541647 -3.4.13.9 * sus scrofa 223.0 111.500000295 2 PMID:17377743;PMID:4778946 -3.4.14.1 * bos taurus 18.6 18.6 1 PMID:23014409 -3.4.14.1 * capra hircus 3.019 3.019 1 PMID:8443565 -3.4.14.1 * rattus norvegicus 91.6 91.6 1 PMID:5026312 -3.4.14.1 * vigna radiata 361.0 361.0 1 * -3.4.14.10 * homo sapiens 4.245 4.245 1 PMID:3511062 -3.4.14.10 * kitasatospora herbaricolor 15.7 15.7 1 PMID:28674833 -3.4.14.10 * mus musculus 12.0 6.034 2 PMID:18822395 -3.4.14.10 * rattus norvegicus 5.4 2.7750000000000004 2 PMID:3511062;PMID:6352701 -3.4.14.11 * lacticaseibacillus casei 71.12 71.12 1 PMID:7765768 -3.4.14.11 * lactobacillus helveticus 90.0 56.1 2 PMID:8574400 -3.4.14.11 * lactococcus lactis 90.0 90.0 1 PMID:8574400 -3.4.14.11 * latilactobacillus sakei 236.5 236.5 1 PMID:11282638 -3.4.14.11 * streptococcus mutans 1070.0 1070.0 1 PMID:27010012 -3.4.14.11 * streptococcus thermophilus 285.0 285.0 1 PMID:9519481 -3.4.14.12 * porphyromonas gingivalis 160.0 74.7 5 PMID:16914159 -3.4.14.2 * cavia porcellus 27.4 27.4 1 * -3.4.14.2 * homo sapiens 70.0 70.0 1 PMID:15487984 -3.4.14.2 * rattus norvegicus 66.2 2.11 5 PMID:11173530;PMID:6342678 -3.4.14.2 * sus scrofa 28.0 14.4015 2 PMID:3722177;PMID:8645718 -3.4.14.4 * capra hircus 0.107 0.0092 7 PMID:17182254 -3.4.14.4 * dictyostelium discoideum 8.3 8.3 1 * -3.4.14.4 * homo sapiens 87.5 33.3 8 PMID:17338643;PMID:19375145;PMID:2906822;PMID:3348886;PMID:9425109 -3.4.14.4 * pediococcus acidilactici 206.67 206.67 1 PMID:30039431 -3.4.14.4 * saccharomyces cerevisiae 0.096 0.096 1 PMID:2186875 -3.4.14.4 * sus scrofa 3.6 2.6 2 PMID:2022295 -3.4.14.4 * sus scrofa domesticus 1.21 0.8049999999999999 4 PMID:20416747 -3.4.14.5 * bos taurus 28.09 28.09 1 PMID:1361338 -3.4.14.5 * gloydius brevicauda 0.0598 0.0598 2 PMID:16828569 -3.4.14.5 * homo sapiens 57.4 25.7 8 PMID:10951221;PMID:12675229;PMID:1358482;PMID:19268648;PMID:1971178;PMID:6991515;PMID:9685737 -3.4.14.5 * lactobacillus helveticus 20.2 20.2 1 * -3.4.14.5 * lactococcus lactis 90.0 65.35 2 * -3.4.14.5 * mus musculus 0.0683 0.0683 1 PMID:2901831 -3.4.14.5 * porphyromonas gingivalis 15.0 15.0 1 PMID:10639438 -3.4.14.5 * rattus norvegicus 61.6 49.4 5 PMID:1354217;PMID:2461166;PMID:2885032;PMID:6338934;PMID:7845210 -3.4.14.5 * saccharomyces cerevisiae 1.153 1.153 1 * -3.4.14.5 * stenotrophomonas maltophilia 350.0 350.0 1 PMID:9010758 -3.4.14.5 * streptococcus anginosus 7.75 7.75 1 PMID:16055397 -3.4.14.5 * streptococcus mitis 56.2 56.2 1 PMID:7027961 -3.4.14.5 * streptococcus salivarius 2.28 2.28 1 PMID:1684633 -3.4.14.5 * streptococcus thermophilus 285.0 285.0 1 PMID:9519481 -3.4.14.5 * sus scrofa 51.9 16.365 8 PMID:12095981;PMID:12690074;PMID:2896517;PMID:486089;PMID:6749833;PMID:7150658;PMID:7896751 -3.4.14.6 * brassica oleracea 0.0267 0.017685 2 * -3.4.14.9 * dictyostelium discoideum 171.0 171.0 1 PMID:10410254 -3.4.14.9 * rattus norvegicus 12.6 7.0915 2 PMID:11843185;PMID:9659384 -3.4.14.9 * sus scrofa 0.516 0.516 1 PMID:3882090 -3.4.15.1 * alitta virens 466.8 466.8 1 PMID:10825662 -3.4.15.1 * bacillus pumilus 4.96 4.96 1 PMID:1368555 -3.4.15.1 * bos taurus 105.1 52.735 2 PMID:11403651;PMID:2851588 -3.4.15.1 * cavia porcellus 0.1128 0.1128 1 PMID:2990346 -3.4.15.1 * homo sapiens 108.0 40.3 14 PMID:1668273;PMID:19071;PMID:2558109;PMID:2823638;PMID:2849459;PMID:2853281;PMID:2989307;PMID:3017438;PMID:3026491;PMID:35818993;PMID:6247934;PMID:6281622;PMID:6289694 -3.4.15.1 * oryctolagus cuniculus 167.0 22.0 5 PMID:169257;PMID:186121;PMID:4351262;PMID:6754723 -3.4.15.1 * papio anubis 10.0 10.0 1 PMID:2823638;PMID:6247934 -3.4.15.1 * pseudomonas sp. 780.0 780.0 1 PMID:9178563 -3.4.15.1 * struthio camelus australis 147.52 147.52 1 * -3.4.15.1 * sus scrofa 36.2 20.4 6 PMID:10287;PMID:1668273;PMID:2439065;PMID:4366382 -3.4.15.5 * escherichia coli 6.38 6.38 1 PMID:8226676 -3.4.16.2 * homo sapiens 0.51 0.51 1 PMID:7341916 -3.4.16.4 * enterococcus faecalis 1.45 1.45 1 PMID:97082 -3.4.16.4 * nonomuraea sp. 40.0 18.0 3 PMID:23497129 -3.4.16.4 * streptomyces sp. 19.8 19.8 1 PMID:4464852 -3.4.16.5 * monascus pilosus 4.0 3.955 2 PMID:15592905 -3.4.16.5 * monascus purpureus 2.13 2.13 1 PMID:14749965 -3.4.16.5 * saccharomyces cerevisiae 305.0 305.0 1 PMID:25214228 -3.4.16.6 * saccharomyces cerevisiae 22.5 22.5 1 PMID:8416959 -3.4.17.1 * aspergillus niger 35.8 10.8 9 PMID:17653510 -3.4.17.1 * bos taurus 64.0 61.9 2 PMID:17134673;PMID:893353 -3.4.17.1 * cosmopolites sordidus 0.0064 0.0064 1 * -3.4.17.1 * homo sapiens 850.0 11.7 3 PMID:14760754;PMID:8806703 -3.4.17.1 * patella vulgata 42.5 42.5 1 PMID:507843 -3.4.17.1 * rattus norvegicus 7.54 7.54 1 PMID:7371832 -3.4.17.1 * squalus acanthias 8.9 8.9 1 PMID:5529813 -3.4.17.1 * struthio camelus 17.24 17.24 1 PMID:8013741 -3.4.17.1 * sus scrofa 108.0 108.0 1 PMID:7274215 -3.4.17.10 * bos taurus 120.0 120.0 1 PMID:6411723 -3.4.17.10 * rattus norvegicus 15.5 15.5 1 PMID:2822027 -3.4.17.11 * flavobacterium sp. 39.43 39.43 1 PMID:26657 -3.4.17.11 * pseudomonas sp. 215.0 215.0 1 PMID:3838935 -3.4.17.11 * stutzerimonas stutzeri 725.0 725.0 1 PMID:5129727 -3.4.17.12 * homo sapiens 19.0 14.0 3 PMID:17208058;PMID:7674953 -3.4.17.13 * novosphingobium aromaticivorans 230.0 30.0 3 PMID:24123814 -3.4.17.15 * homo sapiens 2800.0 1404.35 2 PMID:8806703 -3.4.17.18 * thermoactinomyces vulgaris 8.2 8.2 1 PMID:15721771 -3.4.17.19 * trypanosoma cruzi 85.0 44.6 2 PMID:17007610 -3.4.17.2 * anopheles stephensi 15200.0 8978.5 2 PMID:23569111 -3.4.17.2 * asterias amurensis 460.0 460.0 1 PMID:12381380 -3.4.17.2 * bos taurus 175.0 175.0 1 * -3.4.17.2 * homo sapiens 1192.0 1027.0 2 PMID:17398 -3.4.17.2 * scyliorhinus canicula 300.0 300.0 1 * -3.4.17.2 * struthio camelus 25.83 25.83 1 PMID:8697097 -3.4.17.20 * homo sapiens 2000.0 9.7 4 PMID:1939207;PMID:8195249;PMID:9442053 -3.4.17.21 * rattus norvegicus 3.6e-06 1.8269999999999998e-06 2 PMID:2250024;PMID:8263527 -3.4.17.25 * silene vulgaris 0.044 0.026299999999999997 2 PMID:12620355 -3.4.17.3 * homo sapiens 105.3 79.65 4 PMID:1164026;PMID:148463;PMID:15718415 -3.4.17.4 * mus musculus 8.45e-06 1.0165e-06 6 PMID:9448061 -3.4.17.4 * saccharomyces cerevisiae 230.0 230.0 1 PMID:4961236 -3.4.17.6 * prescottella equi 0.07 0.07 1 * -3.4.17.6 * soil bacterium 8.3 8.3 1 PMID:5806587 -3.4.17.8 * streptomyces albus 400.0 400.0 1 PMID:4919965 -3.4.18.1 * bos taurus 12.0 11.0 2 PMID:1122298;PMID:12811 -3.4.18.1 * paralichthys olivaceus 3457.0 1910.75 2 PMID:18674630 -3.4.18.1 * rattus norvegicus 18.3 10.530000000000001 2 PMID:4346573;PMID:4429705 -3.4.19.1 * bos taurus 1490.0 1490.0 1 PMID:9636668 -3.4.19.1 * cucumis sativus 1.9 1.9 1 PMID:12966075 -3.4.19.1 * pyrococcus horikoshii 17026.0 162.0 28 PMID:9651372 -3.4.19.1 * rattus norvegicus 12.86 12.86 1 PMID:1547272 -3.4.19.1 * saccharolobus solfataricus 4.8 2.4499999999999997 4 PMID:20941418;PMID:22655081 -3.4.19.1 * streptomyces morookaense 186.0 19.0 7 PMID:16503293 -3.4.19.1 * sus scrofa 109.2 109.2 1 PMID:7906149 -3.4.19.11 * lysinibacillus sphaericus 13.9 8.0 3 PMID:8503890 -3.4.19.12 * bos taurus 25.0 1.355 8 PMID:2539853;PMID:2868755;PMID:7999048;PMID:8639624 -3.4.19.12 * homo sapiens 110.0 30.0 5 PMID:8639624 -3.4.19.12 * saccharomyces cerevisiae 1.72 1.665 2 PMID:17709260 -3.4.19.13 * bacillus amyloliquefaciens 6.7 6.7 1 PMID:28120195 -3.4.19.13 * bacillus licheniformis 1.8 1.8 1 PMID:28120195 -3.4.19.13 * bacillus subtilis 5.0 5.0 1 PMID:28120195 -3.4.19.13 * bacillus velezensis 6.3 6.3 1 PMID:28120195 -3.4.19.13 * pseudomonas fluorescens 31.06 31.06 1 PMID:24232936 -3.4.19.13 * pseudomonas protegens 31.06 31.06 1 PMID:24232936 -3.4.19.3 * bacillus subtilis 21.2 21.2 1 PMID:1362573 -3.4.19.3 * bos taurus 3633.0 340.0 3 PMID:17119851;PMID:9597758 -3.4.19.3 * cavia porcellus 0.323 0.323 1 PMID:2862039 -3.4.19.3 * gallus gallus 3.45 3.45 1 PMID:6131954 -3.4.19.3 * homo sapiens 1.093 1.093 1 PMID:1675162 -3.4.19.3 * pseudomonas fluorescens 73.7 73.7 1 PMID:7909543 -3.4.19.3 * streptococcus pyogenes 20.8 20.8 1 PMID:1353731 -3.4.19.3 * thermococcus litoralis 3.5 3.5 1 PMID:11057915 -3.4.19.5 * rattus norvegicus 0.007 0.007 1 * -3.4.19.6 * bos taurus 0.0209 0.0209 1 PMID:9597758 -3.4.19.6 * cavia porcellus 0.3237 0.3237 1 PMID:2862039 -3.4.19.7 * rattus norvegicus 12.86 12.86 1 PMID:1547272 -3.4.19.9 * rattus norvegicus 5.139 5.139 1 PMID:8343522 -3.4.21.1 * bos taurus 84.0 40.3 4 PMID:12452808 -3.4.21.1 * camelus dromedarius 78.4 78.4 1 PMID:10724334 -3.4.21.1 * carassius auratus 981.8 292.85 4 * -3.4.21.1 * daphnia magna 0.3221 0.3221 1 PMID:15050516 -3.4.21.1 * dosidicus gigas 1.59 1.59 1 PMID:30263367 -3.4.21.1 * gadus morhua 178.0 166.0 2 PMID:1764912 -3.4.21.1 * panulirus interruptus 4.5 4.5 1 PMID:25877639 -3.4.21.1 * pterygoplichthys disjunctivus 65.4 65.4 1 PMID:22752357 -3.4.21.1 * sardinops caeruleus 168.0 83.5 4 * -3.4.21.1 * sardinops sagax 43.0 24.5 2 * -3.4.21.1 * sepia officinalis 69.0 15.0 3 * -3.4.21.1 * struthio camelus 1800.0 1036.5 4 PMID:18598777 -3.4.21.10 * bos taurus 92.9 92.9 1 PMID:6802470 -3.4.21.10 * homo sapiens 150.0 99.615 2 PMID:6802470;PMID:6803760 -3.4.21.10 * sus scrofa 37.0 24.5 2 PMID:6751982;PMID:7007201 -3.4.21.100 * grifola frondosa 4920.0 4920.0 1 PMID:15896366 -3.4.21.102 * spinacia oleracea 7e-06 7e-06 1 PMID:15726567 -3.4.21.106 * rattus norvegicus 10.67 10.67 1 PMID:9003440 -3.4.21.107 * bacillus subtilis 79.3 79.3 1 * -3.4.21.107 * escherichia coli 0.473 0.018 5 PMID:19233659 -3.4.21.112 * homo sapiens 0.2 0.022 3 PMID:16973377 -3.4.21.118 * mus musculus 6.26 3.745 2 PMID:9556608 -3.4.21.119 * mus musculus 0.0011 0.0011 1 PMID:9507064 -3.4.21.120 * xenopus laevis 2.53 2.53 1 PMID:1581303 -3.4.21.123 * heyndrickxia coagulans 6600.0 6600.0 1 * -3.4.21.19 * bacillus intermedius 1.02 1.02 1 PMID:14640964 -3.4.21.19 * bacillus licheniformis 360.0 360.0 1 PMID:11004534 -3.4.21.19 * enterococcus faecalis 20140.0 20140.0 1 PMID:15601711 -3.4.21.19 * staphylococcus aureus 800.0 800.0 1 PMID:11004534 -3.4.21.20 * canis lupus familiaris 6.51 6.51 1 PMID:11703184 -3.4.21.20 * homo sapiens 148.0 22.240000000000002 4 PMID:10822079;PMID:19528350 -3.4.21.20 * oryctolagus cuniculus 3.2 3.2 1 PMID:7576231 -3.4.21.25 * cucumis melo 3.26 1.9849999999999999 2 PMID:28428129 -3.4.21.25 * cucumis trigonus 9742.0 3155.0 3 PMID:16603211 -3.4.21.26 * aspergillus niger 0.01 0.01 1 PMID:19757411 -3.4.21.26 * aspergillus oryzae 3650.0 1850.0 2 PMID:24241934 -3.4.21.26 * bos taurus 2.87 2.87 1 PMID:7835390 -3.4.21.26 * coprinopsis clastophylla 61.3 52.1 3 PMID:22923115 -3.4.21.26 * elizabethkingia meningoseptica 65.0 65.0 1 PMID:1569074 -3.4.21.26 * homo sapiens 4.066 2.733e-06 33 PMID:15147213;PMID:20362629 -3.4.21.26 * mus musculus 5.53 5.53 1 PMID:1644866 -3.4.21.26 * myxococcus xanthus 226.0 114.9 2 PMID:27693621 -3.4.21.26 * ovis aries 45.0 25.2 2 PMID:12173;PMID:2300 -3.4.21.26 * pseudomonas sp. 45.6 45.6 1 * -3.4.21.26 * setaria cervi 225.93 115.51350000000001 2 PMID:29273505 -3.4.21.26 * sus scrofa 24.7 0.0033 17 PMID:18657187;PMID:2090162 -3.4.21.27 * homo sapiens 2.83 2.83 1 PMID:1645530 -3.4.21.32 * leptuca pugilator 29000.0 29000.0 1 PMID:8034725 -3.4.21.32 * novoden modestrus 10550.0 10550.0 1 PMID:12297025 -3.4.21.32 * paralithodes camtschaticus 1330.0 673.7 2 PMID:7953075 -3.4.21.34 * homo sapiens 81.0 28.9 3 PMID:11379773;PMID:12002409;PMID:9514601 -3.4.21.34 * rattus norvegicus 1.8 1.8 1 PMID:2597701 -3.4.21.35 * homo sapiens 96.5 47.0 3 PMID:12218299;PMID:2288765;PMID:3937523;PMID:9535704 -3.4.21.35 * rattus norvegicus 323.0 319.0 2 PMID:3237072 -3.4.21.36 * gadus morhua 7.0 7.0 1 PMID:2085959 -3.4.21.36 * ovis aries 7.21 7.21 1 PMID:9787815 -3.4.21.36 * salmo salar 1.31 1.31 1 PMID:9628006 -3.4.21.36 * scyliorhinus canicula 29.0 26.0 2 PMID:8541981 -3.4.21.37 * equus caballus 2.59 2.59 1 PMID:19409585 -3.4.21.37 * homo sapiens 875.0 437.5902 2 PMID:16945464;PMID:3852649 -3.4.21.39 * homo sapiens 1010.0 519.0 4 PMID:11722576;PMID:2425663;PMID:8495723;PMID:9352125 -3.4.21.4 * albatrossia pectoralis 8.9 8.9 1 PMID:19585993 -3.4.21.4 * balistes capriscus 4.03 4.03 1 * -3.4.21.4 * boops boops 5.2 5.2 1 PMID:19898990 -3.4.21.4 * channa argus 502.0 502.0 1 PMID:22155550 -3.4.21.4 * cirrhinus mrigala 3.07 3.07 1 PMID:25577096 -3.4.21.4 * eleginus gracilis 18.0 18.0 1 * -3.4.21.4 * engraulis japonicus 9.26 7.055 2 PMID:11330348 -3.4.21.4 * epinephelus coioides 43.24 43.24 1 PMID:22068456 -3.4.21.4 * euphausia pacifica 92.0 64.0 3 PMID:17987272 -3.4.21.4 * gadus chalcogrammus 50.0 25.3 2 * -3.4.21.4 * gadus macrocephalus 24.0 24.0 1 * -3.4.21.4 * gadus morhua 339.0 155.7 3 PMID:2707266 -3.4.21.4 * lateolabrax japonicus 68.1 53.199999999999996 2 PMID:21515400 -3.4.21.4 * lutjanus vitta 434.7 434.7 1 * -3.4.21.4 * lymantria dispar 115.6 61.5 2 PMID:7711746 -3.4.21.4 * mustelus mustelus 21.65 21.65 1 PMID:20405833 -3.4.21.4 * oncorhynchus keta 6.43 5.895 4 PMID:17827714 -3.4.21.4 * oncorhynchus masou 156.0 156.0 1 PMID:19680768 -3.4.21.4 * oncorhynchus tshawytscha 0.47 0.47 1 PMID:16458561 -3.4.21.4 * oreochromis niloticus 23.7 23.7 1 PMID:25005977 -3.4.21.4 * patiria pectinifera 25.0 25.0 1 PMID:12031475 -3.4.21.4 * pterygoplichthys disjunctivus 15.34 15.34 1 PMID:23790871 -3.4.21.4 * sardinella aurita 61.83 35.94 3 PMID:20711672 -3.4.21.4 * sardinops caeruleus 6.5 6.5 1 * -3.4.21.4 * sepia officinalis 3.12 3.12 1 * -3.4.21.4 * silurus glanis 205.0 109.0 3 * -3.4.21.4 * sitophilus zeamais 529.0 529.0 1 PMID:19835976 -3.4.21.4 * streptomyces griseus 237300.0 37.76 4 PMID:12885239;PMID:18261455;PMID:21767670 -3.4.21.4 * streptomyces omiyaensis 501.5 501.5 1 PMID:21767670 -3.4.21.4 * sus scrofa 0.9397 0.91835 2 PMID:7782340 -3.4.21.4 * thunnus albacares 10.07 7.77 3 PMID:16500127 -3.4.21.4 * thunnus tonggol 36.15 36.15 1 PMID:16848554 -3.4.21.48 * kluyveromyces lactis 47500.0 1659.8 4 PMID:32958394 -3.4.21.48 * saccharomyces cerevisiae 14.3 12.95 2 PMID:371621;PMID:6993457 -3.4.21.5 * bos taurus 0.019 0.019 1 PMID:11676542 -3.4.21.50 * lysobacter sp. 5.6 4.949999999999999 2 PMID:12127482;PMID:15262946 -3.4.21.53 * brevibacillus thermoruber 697.6 482.65 2 PMID:14764100 -3.4.21.57 * spinacia oleracea 4.5 4.5 1 PMID:16664908 -3.4.21.59 * homo sapiens 1000.0 1000.0 1 PMID:16517749 -3.4.21.59 * mus musculus 5.5e-08 5.5e-08 1 PMID:22086176 -3.4.21.59 * sus scrofa 3930.0 3930.0 1 PMID:10824103 -3.4.21.62 * alkalimonas collagenimarina 143.0 10.0 5 PMID:19888572 -3.4.21.62 * arabidopsis thaliana 9.23 9.23 1 PMID:26662452 -3.4.21.62 * bacillus licheniformis 80.0 15.115 4 PMID:20087508;PMID:37585472 -3.4.21.62 * bacillus sp. (in: firmicutes) 58.0 58.0 1 PMID:3909844 -3.4.21.62 * bacillus subtilis 14516.0 876.0 5 PMID:15649780;PMID:30502512;PMID:37517759 -3.4.21.62 * fictibacillus arsenicus 117.0 117.0 1 PMID:37649135 -3.4.21.62 * komagataella pastoris 6.0 6.0 1 PMID:20472730 -3.4.21.62 * rhizopus microsporus var. rhizopodiformis 696.0 348.235 2 PMID:17127629 -3.4.21.62 * shewanella frigidimarina 0.52 0.52 1 * -3.4.21.62 * shouchella clausii 6852.0 6852.0 1 PMID:15988584 -3.4.21.62 * thermococcus kodakarensis 3100.0 1805.0 2 PMID:20100702 -3.4.21.63 * aspergillus oryzae 750.0 92.73 5 PMID:18226921;PMID:30584796 -3.4.21.63 * aspergillus terreus 177.53 148.9 3 PMID:28324360;PMID:32115548 -3.4.21.63 * streptomyces sp. m30 29.07 29.07 1 PMID:26215268 -3.4.21.64 * parengyodontium album 4018.0 47.8 4 PMID:16367747;PMID:31706815;PMID:36327974 -3.4.21.64 * serratia sp. (in: enterobacteria) 88.6 88.6 1 PMID:16367747 -3.4.21.66 * aspergillus terreus 177.53 106.2 2 PMID:32115548 -3.4.21.66 * geobacillus sp. gs53 137.8 137.8 1 PMID:33507494 -3.4.21.66 * geobacillus stearothermophilus 59022.0 59022.0 1 PMID:33672726 -3.4.21.66 * laceyella sacchari 1483.0 334.0 4 PMID:24084004;PMID:24646757 -3.4.21.66 * nocardiopsis alba 3312.0 3312.0 1 PMID:33316342 -3.4.21.66 * nocardiopsis dassonvillei 3028.0 3028.0 1 PMID:32145232 -3.4.21.66 * nocardiopsis sp. mit-7 13052.4 3152.8 4 PMID:37060510 -3.4.21.66 * priestia megaterium 897.0 897.0 1 PMID:33339223 -3.4.21.66 * stenotrophomonas acidaminiphila 6087.0 1537.81 6 PMID:35707314 -3.4.21.68 * homo sapiens 7.4 3.8485 2 PMID:1525179;PMID:21120587 -3.4.21.69 * bos taurus 57.3 57.3 1 PMID:25349251 -3.4.21.71 * bos taurus 4.76 4.76 1 PMID:11838546 -3.4.21.74 * calloselasma rhodostoma 696.0 364.85 2 PMID:1011992;PMID:17707656 -3.4.21.74 * daboia russelii russelii 49.0 31.0 2 PMID:18249434 -3.4.21.74 * gloydius shedaoensis 506.0 506.0 1 PMID:19639313 -3.4.21.74 * trimeresurus albolabris 192.3 150.45 2 PMID:22610139 -3.4.21.75 * homo sapiens 57.0 57.0 1 PMID:24666235 -3.4.21.75 * mus musculus 0.35 0.1750125 2 PMID:10958789;PMID:19070914 -3.4.21.77 * homo sapiens 0.004 0.004 1 PMID:18051307 -3.4.21.79 * homo sapiens 82.0 55.5 2 PMID:14752093 -3.4.21.82 * streptomyces griseus 137.0 137.0 1 PMID:3149277 -3.4.21.83 * escherichia coli 570.0 231.5 12 PMID:23123472 -3.4.21.83 * rhodococcus erythropolis 3690.0 1330.0 12 PMID:23123472 -3.4.21.83 * serratia marcescens 340.0 35.5 12 PMID:23123472 -3.4.21.83 * serratia proteamaculans 72.6 72.6 1 PMID:24184401 -3.4.21.83 * stenotrophomonas maltophilia 3500.0 2425.0 12 PMID:23123472 -3.4.21.83 * trypanosoma brucei 0.0279 0.0279 1 PMID:19819899 -3.4.21.83 * trypanosoma evansi 0.017 0.017 1 PMID:15644339 -3.4.21.83 * xenorhabdus nematophila 176.0 176.0 1 PMID:11872480 -3.4.21.89 * escherichia coli 13.6 13.6 1 PMID:3522590 -3.4.21.9 * bos taurus 9000.0 4110.0 4 PMID:15129728;PMID:16489914;PMID:889800 -3.4.21.9 * homo sapiens 2100.0 2100.0 1 PMID:16489914 -3.4.21.9 * sus scrofa 330.0 165.0225 2 PMID:21790013;PMID:4200635 -3.4.21.91 * dengue virus 59.3 59.3 1 PMID:24352016 -3.4.21.93 * mus musculus 8000.0 4022.225 2 PMID:15358360;PMID:9882569 -3.4.21.94 * mus musculus 0.015 0.015 1 PMID:9422738 -3.4.21.95 * macrovipera lebetinus 678.16 4.9 3 PMID:25917874;PMID:9920400 -3.4.21.96 * enterococcus faecalis 1448.0 1448.0 1 PMID:30726306 -3.4.21.98 * hepacivirus hominis 0.05 0.05 1 PMID:8861916 -3.4.21.99 * halocynthia roretzi 2.0 2.0 1 PMID:6365918 -3.4.22.1 * apostichopus japonicus 96.7 48.945 2 * -3.4.22.1 * bos taurus 56.9 56.9 1 PMID:14569304 -3.4.22.1 * bubalus bubalis 1.538 0.71 5 PMID:3023303;PMID:8936819;PMID:9594426 -3.4.22.1 * capra hircus 40.0 0.562 9 PMID:24642566;PMID:24913985;PMID:25181676;PMID:9305539 -3.4.22.1 * cyprinus carpio 2.56 0.817 4 * -3.4.22.1 * heliocidaris crassispina 0.0667 0.0667 1 * -3.4.22.1 * homo sapiens 7500.0 0.693 13 PMID:16315320;PMID:18809746;PMID:3196286;PMID:37459182 -3.4.22.1 * meretrix meretrix 74.4 74.4 1 PMID:20853148 -3.4.22.1 * oryctolagus cuniculus 0.809 0.809 1 PMID:4062307 -3.4.22.1 * penaeus vannamei 0.6669 0.2 5 PMID:21946097 -3.4.22.1 * rattus norvegicus 2.75 0.732 6 PMID:42540;PMID:7767785 -3.4.22.1 * sus scrofa 7.8 0.27 3 PMID:457630 -3.4.22.10 * streptococcus pyogenes 12500.0 6420.5 2 PMID:19237546;PMID:35008838 -3.4.22.14 * actinidia chinensis 0.197 0.0455 6 * -3.4.22.15 * apostichopus japonicus 59.9 59.9 1 PMID:18540081 -3.4.22.15 * gallus gallus 2500.0 2500.0 1 PMID:3676277 -3.4.22.15 * homo sapiens 85081.0 85081.0 1 PMID:38271604 -3.4.22.15 * hypophthalmichthys molitrix 6.0 3.06 2 PMID:17147449 -3.4.22.15 * oryctolagus cuniculus 34.4 34.4 1 PMID:6421281 -3.4.22.15 * rattus norvegicus 26.2 2.35 3 PMID:1426527;PMID:15835;PMID:3759937 -3.4.22.15 * spodoptera frugiperda 11.0 0.36 9 PMID:16274658 -3.4.22.16 * bos taurus 286.0 286.0 1 PMID:8713750 -3.4.22.16 * bubalus bubalis 11.95 11.95 1 PMID:32072025 -3.4.22.16 * capra hircus 0.024 0.02291 5 PMID:24642566;PMID:24913985;PMID:25181676;PMID:26193682 -3.4.22.16 * cyprinus carpio 29.7 14.850054499999999 2 PMID:1499287;PMID:9206588 -3.4.22.16 * homo sapiens 3.5 1.95 5 PMID:15127951;PMID:6165352 -3.4.22.16 * oryctolagus cuniculus 7.45 3.7294 2 PMID:12565709;PMID:659418 -3.4.22.16 * rattus norvegicus 7.714 7.714 1 PMID:6370990 -3.4.22.16 * sus scrofa 20.0 20.0 1 PMID:6746670 -3.4.22.2 * carica papaya 221.7 25.89 10 PMID:15000480;PMID:15932346;PMID:19272620;PMID:20304972;PMID:25661879;PMID:37511006 -3.4.22.26 * homo sapiens 47.0 47.0 1 PMID:9259116 -3.4.22.26 * rattus norvegicus 332.25 2.32 25 PMID:18589871;PMID:29411223 -3.4.22.27 * bos taurus 0.582 0.582 1 PMID:2690828 -3.4.22.27 * homo sapiens 7200.0 7200.0 1 PMID:8444861 -3.4.22.29 * enterovirus c 550.0 550.0 1 PMID:2831385 -3.4.22.29 * human rhinovirus sp. 8.8 8.8 1 PMID:8338854 -3.4.22.3 * ficus carica 6824.0 0.146 13 PMID:18991449;PMID:21665232;PMID:37511006 -3.4.22.3 * ficus pumila var. awkeotsang 104.73 104.73 1 PMID:36071690 -3.4.22.32 * ananas comosus 859.44 72.5 6 PMID:14616080;PMID:27855525;PMID:37511006;PMID:9619588 -3.4.22.33 * ananas comosus 2512.44 6.13 11 PMID:26345013;PMID:27855525;PMID:33713245;PMID:36144767;PMID:38320436 -3.4.22.33 * bromelia karatas 10.0 7.225 2 PMID:30263775 -3.4.22.33 * bromelia pinguin 22.83 15.37 2 PMID:30263775 -3.4.22.34 * bos taurus 1.53 1.53 1 PMID:11983426 -3.4.22.34 * haemaphysalis longicornis 0.642 0.00041 3 PMID:17681230;PMID:18222467 -3.4.22.34 * haemonchus contortus 1.35 1.35 1 PMID:16650340 -3.4.22.34 * phaseolus vulgaris 7.04 5.77 2 PMID:11501761;PMID:9874222 -3.4.22.34 * sus scrofa 8.1 7.55 2 PMID:11501761;PMID:9065484 -3.4.22.35 * entamoeba histolytica 2800.0 680.0 6 PMID:10542062;PMID:11812234;PMID:18824105 -3.4.22.37 * porphyromonas gingivalis 45.5 42.099999999999994 4 PMID:9705298 -3.4.22.38 * homo sapiens 15.0 7.5035 2 PMID:9153258 -3.4.22.39 * unidentified adenovirus 48.9 48.9 1 PMID:8550615 -3.4.22.40 * aspergillus niger 189.0 189.0 1 * -3.4.22.40 * cricetulus griseus 1.09 1.09 1 PMID:6169344 -3.4.22.40 * homo sapiens 815.0 815.0 1 PMID:8639621 -3.4.22.47 * porphyromonas gingivalis 0.356 0.308 2 PMID:7831206;PMID:9538207 -3.4.22.51 * trypanosoma cruzi 84.0 0.1 3 PMID:12460772;PMID:2407295 -3.4.22.6 * carica papaya 0.154 0.154 1 PMID:6437389 -3.4.22.63 * channa striata 0.0025 0.0025 1 PMID:23253492 -3.4.22.67 * zingiber officinale 3573.0 42.8 4 PMID:25475843;PMID:38512162 -3.4.22.7 * asclepias curassavica 10880.0 246.4 4 PMID:15517987;PMID:19204833;PMID:36060760 -3.4.22.7 * asclepias syriaca 6300.0 5200.0 2 PMID:36921 -3.4.22.70 * staphylococcus aureus 0.0255 0.0255 1 PMID:14769030 -3.4.22.8 * clostridium perfringens 123.5 14.865 4 PMID:19850615 -3.4.22.8 * hathewaya histolytica 625.5 30.6595 6 PMID:20940055;PMID:4971659;PMID:762145 -3.4.23.1 * saurida micropectoralis 208.78 159.18 3 PMID:34274702 -3.4.23.1 * sus scrofa 3.32 3.3099999999999996 2 PMID:38888698 -3.4.23.12 * nepenthes distillatoria 874.0 841.5 2 PMID:32365700 -3.4.23.15 * homo sapiens 818.0 818.0 1 PMID:1732722 -3.4.23.15 * mus musculus 6.4e-05 5.5499999999999994e-05 2 PMID:26216430 -3.4.23.15 * rattus norvegicus 4.29 4.29 1 PMID:1848255 -3.4.23.16 * human immunodeficiency virus 1 0.036 0.036 1 PMID:7854194 -3.4.23.18 * aspergillus luchuensis 8.64 8.64 1 * -3.4.23.18 * aspergillus niger 38362.0 21607.0 2 PMID:31374272;PMID:36864487 -3.4.23.18 * aspergillus oryzae 867.0 242.0 3 PMID:25177;PMID:28821318 -3.4.23.20 * penicillium sp. xt7 4289.0 3227.5 8 PMID:33348133 -3.4.23.21 * rhizopus microsporus 5248.0 5248.0 1 PMID:31661372 -3.4.23.23 * rhizomucor miehei 1057.0 1057.0 1 PMID:27165660 -3.4.23.34 * cavia porcellus 2.2 2.2 1 PMID:7545776 -3.4.23.38 * plasmodium falciparum 0.04 0.04 1 PMID:2007860 -3.4.23.4 * rhizopus microsporus 7.272 4.6295 2 PMID:25035104 -3.4.23.40 * cynara cardunculus 91.8 91.8 2 PMID:8654427 -3.4.23.40 * triticum aestivum 0.703 0.703 1 PMID:24212424 -3.4.23.45 * homo sapiens 0.015 0.015 1 PMID:12423367 -3.4.23.46 * mus musculus 0.02 0.015 2 PMID:18184658 -3.4.23.49 * escherichia coli 58.7 58.7 1 PMID:3056908 -3.4.23.49 * phanerodontia chrysosporium 750.0 750.0 1 PMID:28193432 -3.4.23.5 * clupea harengus 8263.0 8263.0 1 PMID:11207447 -3.4.23.5 * gallus gallus 0.101 0.101 1 * -3.4.23.5 * homarus americanus 1.113 0.561015 2 PMID:20817002 -3.4.23.5 * patiria pectinifera 1.15 1.15 1 PMID:17977858 -3.4.23.5 * tilapia sp. 0.077 0.057749999999999996 2 * -3.4.24.1 * bothrops atrox 8430.0 8430.0 1 PMID:31561469 -3.4.24.11 * homo sapiens 1.8e-06 1.8e-06 1 PMID:17906676 -3.4.24.11 * lactococcus lactis 0.203 0.203 1 PMID:8806762 -3.4.24.11 * rattus norvegicus 0.00014 6e-05 3 PMID:17952634 -3.4.24.11 * sus scrofa 26.3 13.229000000000001 2 PMID:6419725 -3.4.24.12 * paracentrotus lividus 179.0 179.0 1 PMID:2925668 -3.4.24.12 * strongylocentrotus purpuratus 1.44 1.44 1 PMID:20058 -3.4.24.15 * bacillus licheniformis 236.0 236.0 1 * -3.4.24.15 * geobacillus sp. 30.4 24.95 2 PMID:17284829 -3.4.24.15 * mus musculus 0.1 0.1 1 PMID:17620116 -3.4.24.15 * rattus norvegicus 28.7 20.3 3 PMID:1355047;PMID:2803255;PMID:6349998 -3.4.24.15 * sus scrofa 0.00037 0.00037 1 PMID:8297391 -3.4.24.16 * mus musculus 0.0088 0.0088 1 PMID:17620116 -3.4.24.16 * rattus norvegicus 6.9 0.0226 5 PMID:1355047;PMID:3409880;PMID:3525564;PMID:7730308;PMID:8425555 -3.4.24.16 * sus scrofa 0.298 0.15889999999999999 2 PMID:1905921;PMID:8869556 -3.4.24.17 * homo sapiens 18.6 9.300249 2 PMID:17602907;PMID:17710450 -3.4.24.18 * homo sapiens 20800.0 2700.0 3 PMID:17976009 -3.4.24.18 * mus musculus 25000.0 4.2 9 PMID:10837482;PMID:12437102;PMID:17976009;PMID:1894622;PMID:8161197 -3.4.24.20 * grifola frondosa 227.3 213.75 2 PMID:31484223 -3.4.24.24 * bos taurus 1045.0 1045.0 1 PMID:15030172 -3.4.24.24 * homo sapiens 11.8 6.0840000000000005 2 PMID:12509986 -3.4.24.25 * moritella viscosa 2020.0 2020.0 1 PMID:19147307 -3.4.24.25 * vibrio proteolyticus 1736.0 1736.0 1 PMID:18768160 -3.4.24.26 * pseudomonas aeruginosa 99610.0 2389.0 7 PMID:15830941;PMID:19332295;PMID:22326423;PMID:24267565;PMID:25979480;PMID:6409834 -3.4.24.27 * bacillus thermoproteolyticus 12000.0 9340.0 7 PMID:15836734;PMID:16169746;PMID:18974160;PMID:20214932;PMID:21150094;PMID:22037182;PMID:22648563 -3.4.24.27 * halobacillus sp. 3077.0 855.0 7 PMID:23357731 -3.4.24.27 * thermaerobacillus caldiproteolyticus 686.52 569.95 3 PMID:34940675 -3.4.24.28 * bacillus amyloliquefaciens 11280.0 11280.0 1 PMID:23813340 -3.4.24.28 * bacillus cereus 3556.0 2536.935 2 PMID:25802851;PMID:31673794 -3.4.24.28 * bacillus intermedius 17.4 0.0282 7 PMID:21166648 -3.4.24.28 * bacillus nematocida 55.6 55.6 1 PMID:16775750 -3.4.24.28 * bacillus sp. zg20 26655.0 26655.0 1 PMID:31050583 -3.4.24.28 * geobacillus stearothermophilus 608.0 81.9 7 PMID:15642473;PMID:17163509 -3.4.24.3 * cytophaga sp. 7.02 7.02 1 PMID:7764338 -3.4.24.3 * hathewaya histolytica 2.6 2.6 2 PMID:34624941 -3.4.24.3 * lysinibacillus sphaericus 199.0 199.0 1 PMID:32741269 -3.4.24.3 * vibrio pomeroyi 325.32 99.32 9 PMID:35285716 -3.4.24.40 * citrobacter freundii 2174.0 2174.0 1 PMID:4212288 -3.4.24.40 * pseudomonas fluorescens 3.98 3.98 1 PMID:9058196 -3.4.24.40 * serratia marcescens 20492.0 20492.0 1 PMID:33835269 -3.4.24.40 * thermoascus aurantiacus 2310.0 2310.0 1 PMID:19746980 -3.4.24.56 * rattus norvegicus 0.22 0.22 1 PMID:19750477 -3.4.24.60 * xenopus laevis 0.1826 0.1826 1 PMID:1729723 -3.4.24.63 * mus musculus 1.82 1.0935000000000001 2 PMID:1894622 -3.4.24.64 * neurospora crassa 2.98e-05 2.98e-05 1 PMID:2967109 -3.4.24.64 * saccharomyces cerevisiae 26.78 2.35 7 PMID:2007593 -3.4.24.64 * trichomonas vaginalis 0.0023 0.0023 1 PMID:19096520 -3.4.24.66 * hippocampus erectus 0.525 0.2365 4 PMID:33960059 -3.4.24.67 * danio rerio 900.0 900.0 1 PMID:19021768 -3.4.24.67 * hippocampus erectus 0.32 0.1935 4 PMID:33960059 -3.4.24.69 * clostridium botulinum 15.8 15.8 1 PMID:19450643 -3.4.24.70 * escherichia coli 0.289 0.0858 5 PMID:16098472 -3.4.24.71 * homo sapiens 0.0001799 0.0001799 1 PMID:9808768 -3.4.24.71 * rattus norvegicus 0.00127 0.00127 1 PMID:8407980 -3.4.24.72 * agkistrodon contortrix contortrix 11300.0 6080.0 4 * -3.4.24.72 * aspergillus versicolor 3367.2 3367.2 1 PMID:35736159 -3.4.24.72 * bacillus cereus 876.36 876.36 1 PMID:32515847 -3.4.24.73 * bothrops jararaca 400.0 400.0 1 PMID:17055999 -3.4.24.76 * elizabethkingia meningoseptica 0.4 0.4 1 PMID:7771796 -3.4.24.77 * streptomyces rimosus 33.3 6.050000000000001 6 PMID:16521041 -3.4.24.77 * streptomyces septatus 2.81 2.0300000000000002 2 PMID:15639229 -3.4.24.83 * bacillus anthracis 7.12 4.18 2 PMID:25042732 -3.4.24.84 * homo sapiens 173.0 173.0 1 PMID:22355414 -3.4.25.1 * allium sativum 0.0077 0.0077 1 PMID:15161196 -3.4.25.1 * candida albicans 0.228 0.228 1 PMID:10700377 -3.4.25.1 * homo sapiens 71.0 50.0 2 PMID:19811823 -3.4.25.1 * manduca sexta 0.016 0.016 1 PMID:7726556 -3.4.25.1 * methanosarcina thermophila 0.0091 0.0052 2 PMID:9515917 -3.4.25.1 * rhodococcus sp. (in: high g+c gram-positive bacteria) 0.09 0.09 1 PMID:7583123 -3.4.25.1 * spinacia oleracea 0.022 0.022 1 PMID:1400479 -3.4.25.1 * struthio camelus 3.47 3.47 1 PMID:9363639 -3.4.25.1 * trypanosoma brucei 7.51 7.51 1 PMID:9228559 -3.4.26.1 * saccharomyces cerevisiae 0.011 0.011 1 PMID:10747800 -3.5.1.1 * acinetobacter calcoaceticus 70.0 51.0 2 PMID:4770738;PMID:938683 -3.5.1.1 * actinomycetales bacterium 204.0 204.0 1 PMID:25285655 -3.5.1.1 * aspergillus niger 0.82 0.82 1 PMID:17057254 -3.5.1.1 * aspergillus oryzae 742.22 742.22 1 PMID:34110268 -3.5.1.1 * azotobacter vinelandii 2.47 2.47 1 PMID:16345199 -3.5.1.1 * bacillus altitudinis 800.0 414.08 2 PMID:31762381 -3.5.1.1 * bacillus australimaris 585.0 333.335 2 PMID:35718140 -3.5.1.1 * bacillus halotolerans 215.33 135.65 2 PMID:33228468 -3.5.1.1 * bacillus licheniformis 407.6 271.3 2 PMID:25224912 -3.5.1.1 * bacillus sp. pg_02 17.1 17.1 1 * -3.5.1.1 * bacillus subtilis 234.38 118.565 2 PMID:38004285 -3.5.1.1 * cavia porcellus 131.0 131.0 1 PMID:8590375 -3.5.1.1 * chaetomium sp. 1175.0 827.5 2 PMID:34742913 -3.5.1.1 * cupriavidus necator 18.29 6.445 6 * -3.5.1.1 * erwinia aroidea 256.0 256.0 1 PMID:4649741 -3.5.1.1 * escherichia coli 620.0 195.0 4 PMID:15477079;PMID:29101342;PMID:4970225 -3.5.1.1 * helicobacter pylori j99 92.0 92.0 1 * -3.5.1.1 * heyndrickxia coagulans 10.9 10.9 1 PMID:5171719 -3.5.1.1 * lupinus arboreus 2.97 1.4649999999999999 4 PMID:1368361;PMID:7259189 -3.5.1.1 * lupinus polyphyllus 17.9 3.9 3 PMID:3911011 -3.5.1.1 * metapseudomonas otitidis 107.84 107.84 1 PMID:26597158 -3.5.1.1 * mycobacterium gordonae 486.65 251.1 2 PMID:34829099 -3.5.1.1 * nocardiopsis alba 93.28 47.44 2 PMID:25274019 -3.5.1.1 * paenibacillus barengoltzii 35.2 35.2 1 PMID:27919811 -3.5.1.1 * pectobacterium carotovorum 1034.0 21.6 11 PMID:15032742;PMID:20669055;PMID:21048860 -3.5.1.1 * phaseolus vulgaris 846.0 846.0 1 PMID:26413120 -3.5.1.1 * priestia megaterium 215.0 135.35 2 PMID:30568045;PMID:31326332 -3.5.1.1 * proteus vulgaris 300.0 300.0 1 PMID:4550558;PMID:4615245 -3.5.1.1 * pseudomonas aeruginosa 19758.8 5925.0 5 PMID:15469724;PMID:30097831;PMID:33440252 -3.5.1.1 * pseudomonas fluorescens 26.0 26.0 1 PMID:29079538 -3.5.1.1 * pseudomonas sp. pch199 47.18 23.84 2 PMID:36828987 -3.5.1.1 * pyrococcus furiosus 11203.5 6583.2 2 PMID:32311402 -3.5.1.1 * rhizobium etli 20.0 20.0 1 PMID:22450783 -3.5.1.1 * rhizomucor miehei 1.985 1.38235 2 PMID:24362429 -3.5.1.1 * saccharomyces cerevisiae 196.2 196.2 1 PMID:27824095 -3.5.1.1 * serratia marcescens 226.0 7.25 13 PMID:4213333 -3.5.1.1 * staphylococcus sp. 113.1 56.989999999999995 2 PMID:24861344 -3.5.1.1 * streptomyces fradiae 30.6 30.6 1 PMID:27605431 -3.5.1.1 * streptomyces gulbargensis 2053.0 2053.0 1 PMID:24031478 -3.5.1.1 * streptomyces sp. 662.6 662.6 1 * -3.5.1.1 * streptomyces tendae 51.7 51.7 1 PMID:20737924 -3.5.1.1 * stutzerimonas stutzeri 732.3 732.3 1 PMID:7766157 -3.5.1.1 * talaromyces pinophilus 145.0 84.35 2 * -3.5.1.1 * tetrahymena thermophila 59.6 47.85 2 PMID:8012291 -3.5.1.1 * thermococcus gammatolerans 7.622 3.3395 4 * -3.5.1.1 * thermococcus kodakarensis 978.7 760.3 2 PMID:24442710 -3.5.1.1 * thermococcus sibiricus 2164.0 1294.75 4 PMID:34576056;PMID:37298582 -3.5.1.1 * thermus thermophilus 840.0 840.0 1 PMID:11216870 -3.5.1.1 * vibrio cholerae 2120.0 2120.0 1 PMID:29307802 -3.5.1.1 * vigna unguiculata 969.0 49.0 11 * -3.5.1.1 * withania somnifera 1893.0 1893.0 1 PMID:19200159 -3.5.1.1 * wolinella succinogenes 202.0 202.0 1 PMID:11211 -3.5.1.1 * yersinia pseudotuberculosis 106.0 84.35 2 PMID:22226870;PMID:22808465 -3.5.1.10 * escherichia coli 0.174 0.174 1 PMID:7868604 -3.5.1.100 * pseudomonas sp. 4.59 2.3071 2 PMID:15066183 -3.5.1.101 * pseudomonas azotoformans 192.0 96.000447 2 PMID:15066172 -3.5.1.102 * methanocaldococcus jannaschii 6.0 6.0 1 PMID:19309161 -3.5.1.103 * mycobacterium tuberculosis 0.19 0.19 1 PMID:16630724 -3.5.1.105 * pyrococcus horikoshii 2047.3 2047.3 1 PMID:31253675 -3.5.1.105 * shewanella baltica 9.4 0.22 3 PMID:27832730 -3.5.1.105 * vibrio alginolyticus 32.2 32.2 1 * -3.5.1.105 * vibrio parahaemolyticus 31.0 28.1 2 PMID:17334758;PMID:17479220 -3.5.1.107 * pseudomonas putida 0.0193 0.0193 1 PMID:18678916 -3.5.1.108 * aquifex aeolicus 0.84 0.84 1 PMID:11148046 -3.5.1.108 * escherichia coli 2.96 1.9 2 PMID:11148046;PMID:8530464 -3.5.1.108 * pseudomonas aeruginosa 1.33 1.33 1 PMID:9068651 -3.5.1.11 * actinoplanes utahensis 42.8 42.8 1 PMID:17586674 -3.5.1.11 * alcaligenes faecalis 17990.0 9035.0 2 PMID:16139515;PMID:20224955 -3.5.1.11 * bacillus subtilis 4.8 4.8 1 PMID:21978958 -3.5.1.11 * escherichia coli 22240.0 12.0 17 PMID:15178432;PMID:16139515;PMID:16332894;PMID:22228258;PMID:22271751;PMID:22728392;PMID:237220;PMID:4947502;PMID:7546605 -3.5.1.11 * kluyvera cryocrescens 12840.0 48.9 4 PMID:15477078;PMID:15604805;PMID:16139515;PMID:26243007 -3.5.1.11 * lysinibacillus sphaericus 6.9 6.9 1 PMID:30243389 -3.5.1.11 * priestia megaterium 182.0 1.425 12 PMID:1367491;PMID:17186238;PMID:19205746;PMID:4960153 -3.5.1.11 * providencia rettgeri 1975.0 1975.0 1 PMID:16139515 -3.5.1.115 * mycobacterium tuberculosis 10.6 5.365 2 PMID:14556638 -3.5.1.115 * mycolicibacterium smegmatis 3.3 1.6505999999999998 2 PMID:10978158 -3.5.1.116 * glycine max 20.0 20.0 1 PMID:23940254 -3.5.1.116 * oryza sativa 64.0 64.0 1 PMID:23940254 -3.5.1.117 * flavobacterium sp. 2.3 2.3 1 PMID:8285701 -3.5.1.12 * sus scrofa 0.2 0.2 1 * -3.5.1.127 * arabidopsis thaliana 0.000456 4.5e-05 14 PMID:26672615 -3.5.1.128 * pseudomonas aeruginosa 13.6 13.6 1 PMID:28373563 -3.5.1.128 * saccharomyces cerevisiae 8.71 8.71 1 PMID:28373563 -3.5.1.128 * synechocystis sp. pcc 6803 7.8 7.8 1 PMID:28373563 -3.5.1.128 * yersinia enterocolitica 6.5 6.5 1 PMID:28373563 -3.5.1.13 * bos taurus 0.319 0.319 1 PMID:19292875 -3.5.1.13 * electrophorus electricus 27.45 27.45 1 PMID:8294938 -3.5.1.13 * glycine max 0.81 0.81 1 PMID:4473253 -3.5.1.13 * homo sapiens 4.068 0.741 31 PMID:17379201;PMID:18208347;PMID:18452906;PMID:7035166 -3.5.1.13 * nocardia farcinica 20.0 11.2 2 PMID:18942140 -3.5.1.13 * paracoccus sp. m1-1 39.8 39.8 2 PMID:22101784 -3.5.1.13 * platyrrhini 0.016 0.016 1 PMID:108100 -3.5.1.13 * pseudomonas fluorescens 319.2 319.2 1 PMID:6406224 -3.5.1.13 * streptomyces sp. 0.87 0.69 3 PMID:24752846 -3.5.1.137 * achromobacter sp. wm111 7.85 0.161 4 * -3.5.1.137 * arthrobacter sp. rc100 0.388 0.2155 2 PMID:11445174 -3.5.1.137 * aspergillus niger 968.0 485.85 2 PMID:14612234 -3.5.1.137 * blastobacter sp. m501 704.3 353.29999999999995 2 PMID:16348989 -3.5.1.137 * pseudomonas aeruginosa 1201.8 601.24 2 PMID:8407847 -3.5.1.137 * pseudomonas sp. 50432 1016.0 508.25 2 PMID:12149124 -3.5.1.137 * pseudomonas sp. crl-ok 14.1 7.0565 2 PMID:1785941 -3.5.1.137 * rhizobium sp. ac100 30.7 15.375 2 PMID:11872471 -3.5.1.138 * homo sapiens 73.0 37.5 2 PMID:3196715 -3.5.1.138 * sus scrofa 0.0085 0.0085 2 PMID:1435760;PMID:2347395 -3.5.1.14 * burkholderia sp. lp5_18b 949.0 949.0 1 PMID:31200632 -3.5.1.14 * deinococcus radiodurans 15.1 5.32 21 PMID:17129628 -3.5.1.14 * geobacillus sp. 66.4 66.4 1 * -3.5.1.14 * heliothis virescens 2.8e-07 2.8e-07 1 PMID:22056272 -3.5.1.14 * mus musculus 11.7 10.55 2 PMID:17434493 -3.5.1.14 * pseudomonas sp. 0.025 0.012 5 PMID:9214752 -3.5.1.14 * rattus norvegicus 8.33 2.2 3 PMID:14644550;PMID:15938642 -3.5.1.14 * streptomyces mobaraensis 530.0 100.5 56 PMID:16390180;PMID:19734688 -3.5.1.14 * sus scrofa 287.0 85.5 6 PMID:16567407;PMID:18815781;PMID:19818829 -3.5.1.14 * thermococcus litoralis 6.8 0.19 7 PMID:11856837;PMID:21827797 -3.5.1.141 * brucella anthropi 64.29 0.97 3 PMID:10526991 -3.5.1.15 * bos taurus 0.019 0.019 1 PMID:1987315 -3.5.1.15 * columba sp. 0.25 0.25 1 PMID:1255182 -3.5.1.15 * homo sapiens 1557.0 807.0 2 PMID:17027983;PMID:24632142 -3.5.1.15 * macaca mulatta 0.98 0.98 1 PMID:1255182 -3.5.1.15 * mesocricetus auratus 0.29 0.29 1 PMID:1255182 -3.5.1.15 * mus musculus 0.45 0.45 1 PMID:1255182 -3.5.1.15 * oryctolagus cuniculus 0.3 0.3 1 PMID:1255182 -3.5.1.15 * rattus norvegicus 0.47 0.44499999999999995 2 PMID:1255182;PMID:19559 -3.5.1.16 * escherichia coli 2000.0 800.0 3 PMID:13278318;PMID:1551850;PMID:16201833 -3.5.1.16 * saccharolobus solfataricus 0.15 0.14 2 * -3.5.1.17 * achromobacter pestifer 240.0 127.25 2 * -3.5.1.17 * streptomyces mobaraensis 2500.0 2500.0 1 PMID:19433221 -3.5.1.17 * sus scrofa 0.087 0.087 1 PMID:5658148 -3.5.1.18 * haemophilus influenzae 180.0 180.0 1 PMID:16421726 -3.5.1.19 * escherichia coli 27.2 27.2 1 PMID:4399474 -3.5.1.19 * flavobacterium peregrinum 2.17 2.17 1 PMID:4264486;PMID:7374465 -3.5.1.19 * mycobacterium tuberculosis 89.6 85.75 2 PMID:18201201 -3.5.1.19 * oceanobacillus iheyensis 23.3 3.62 5 PMID:23451075 -3.5.1.19 * pseudomonas sp. 37.6 37.6 1 * -3.5.1.19 * saccharomyces cerevisiae 59.4 50.2 3 PMID:17382284;PMID:3036844 -3.5.1.2 * alcaligenes faecalis 0.912 0.503 2 * -3.5.1.2 * anabaena sp. 102.3 64.005 2 PMID:19054111 -3.5.1.2 * aspergillus flavus 613.3 613.3 1 PMID:31130583 -3.5.1.2 * aspergillus oryzae 730.0 51.0 3 PMID:15555943 -3.5.1.2 * aspergillus sojae 720.5 61.900000000000006 8 PMID:23339014 -3.5.1.2 * aspergillus versicolor 398.79 294.795 2 PMID:33389217 -3.5.1.2 * bacillus amyloliquefaciens 196.2 99.05999999999999 2 * -3.5.1.2 * bacillus cereus 58.6 7.44 3 PMID:23873638 -3.5.1.2 * bacillus licheniformis 325.0 325.0 1 PMID:22433447 -3.5.1.2 * bacillus sp. (in: firmicutes) 584.2 584.2 1 PMID:22367638 -3.5.1.2 * bacillus subtilis 89.87 67.375 2 PMID:31846380 -3.5.1.2 * camelus dromedarius 120.0 60.85 2 PMID:31743703 -3.5.1.2 * geobacillus sp. h6a 0.00821 0.00481 2 PMID:35350642 -3.5.1.2 * homo sapiens 2.4 1.54 2 PMID:15246207 -3.5.1.2 * limosilactobacillus reuteri 16.4 8.457999999999998 2 PMID:19784812 -3.5.1.2 * micrococcus luteus 1246.0 1230.0 3 PMID:10049670;PMID:15290324 -3.5.1.2 * pseudomonas aeruginosa 27.1 24.6 2 PMID:4622222 -3.5.1.2 * pseudomonas sp. 36.0 36.0 1 PMID:4650141 -3.5.1.2 * rattus norvegicus 405.0 374.0 4 PMID:12963351;PMID:3899104;PMID:6743288 -3.5.1.2 * sporosarcina pasteurii 234.0 234.0 1 PMID:11786258 -3.5.1.2 * stenotrophomonas maltophilia 325.0 325.0 1 PMID:16012776 -3.5.1.2 * streptomyces roseolus 8711.9 4641.45 2 PMID:38889830 -3.5.1.2 * synechocystis sp. pcc 6803 31.3 30.5 2 PMID:19093079 -3.5.1.2 * trichoderma reesei 40.32 38.385000000000005 2 PMID:23802704 -3.5.1.20 * euglena gracilis 0.0334 0.0334 1 * -3.5.1.20 * francisella tularensis subsp. tularensis 20.0 20.0 1 * -3.5.1.21 * sus sp. 33.5 33.5 1 * -3.5.1.22 * pseudomonas fluorescens 86.9 13.7 5 PMID:102337;PMID:108511;PMID:3128283;PMID:822843 -3.5.1.23 * camelus dromedarius 230.6 230.6 1 PMID:23638321 -3.5.1.23 * cavia porcellus 5.72 3.88 2 PMID:7759519 -3.5.1.23 * drosophila melanogaster 0.00052 0.00052 1 PMID:18184565 -3.5.1.23 * homo sapiens 3.647 0.020949999999999996 4 PMID:10563326;PMID:12815059;PMID:17475390;PMID:7744740 -3.5.1.23 * mus musculus 14.45 1.925e-05 38 PMID:10652340;PMID:18955860 -3.5.1.23 * pseudomonas aeruginosa 186.0 0.22849999999999998 4 PMID:12821326;PMID:19088069;PMID:9603946 -3.5.1.23 * pseudomonas sp. 2.7 2.7 1 PMID:17164222 -3.5.1.23 * rattus norvegicus 16720.0 1.91 5 PMID:10488143;PMID:11328816;PMID:19088069;PMID:21224012 -3.5.1.24 * bacteroides fragilis 160.2 160.2 1 PMID:10993 -3.5.1.24 * bifidobacterium bifidum 6168.0 6168.0 1 PMID:14762068 -3.5.1.24 * bifidobacterium longum 7904.0 3967.0 2 PMID:14762068;PMID:15333949 -3.5.1.24 * bifidobacterium longum subsp. infantis 5389.0 5389.0 1 PMID:14762068 -3.5.1.24 * brevibacillus sp. 13.8 12.2 3 PMID:19142574 -3.5.1.24 * clostridium perfringens 599.2 343.1 2 PMID:37163789;PMID:6016335 -3.5.1.24 * enterococcus faecalis 1390.0 1340.0 2 * -3.5.1.24 * enterococcus faecium 1390.0 1340.0 2 * -3.5.1.24 * lactiplantibacillus plantarum 274.2 274.2 1 * -3.5.1.24 * lentilactobacillus buchneri 51.29 42.19 2 * -3.5.1.24 * ligilactobacillus salivarius 17.7 7.85 6 PMID:23064348 -3.5.1.25 * alteromonas sp. 14.0 14.0 1 PMID:10804240 -3.5.1.25 * chitiniphilus shinanonensis 119.4 13.0 3 PMID:38724455 -3.5.1.25 * escherichia coli 56.0 30.8 2 PMID:236479;PMID:4861885 -3.5.1.25 * vibrio cholerae serotype o1 25.8 25.8 1 PMID:8987551 -3.5.1.26 * bos taurus 0.003 0.003 1 PMID:1554372 -3.5.1.26 * elizabethkingia meningoseptica 25.0 25.0 1 PMID:8250923 -3.5.1.26 * gallus gallus 0.003 0.003 1 PMID:1554372 -3.5.1.26 * homo sapiens 20.0 0.53 10 PMID:1554372;PMID:1859849;PMID:2005122;PMID:2039475;PMID:21658;PMID:6885799;PMID:8131272;PMID:9257709 -3.5.1.26 * mus musculus 0.003 0.003 1 PMID:1554372 -3.5.1.26 * rattus sp. 6.6 3.3015 2 PMID:1554372;PMID:6061403 -3.5.1.26 * spodoptera frugiperda 2.1 2.1 1 PMID:8877373 -3.5.1.26 * sus scrofa 1.55 0.02 3 PMID:1554372;PMID:4724304;PMID:5010303 -3.5.1.28 * bacillus subtilis 46.7 19.990000000000002 4 PMID:803507;PMID:821918 -3.5.1.28 * escherichia coli 0.447 0.447 1 PMID:1102308 -3.5.1.28 * homo sapiens 46.0 1.23 5 PMID:1974148;PMID:6120007;PMID:6152147;PMID:7663175;PMID:8605233 -3.5.1.28 * mus musculus 0.144 0.144 1 PMID:6120007 -3.5.1.28 * pseudomonas aeruginosa 132.0 132.0 1 PMID:17723308 -3.5.1.28 * streptococcus mitis 0.03 0.0100023 4 PMID:15576771;PMID:16530188 -3.5.1.28 * streptococcus pneumoniae 100.0 79.0 2 PMID:1355082 -3.5.1.28 * streptomyces globisporus 0.863 0.402 7 * -3.5.1.29 * mesorhizobium loti 1.89 1.179 2 PMID:18635903 -3.5.1.29 * pseudomonas sp. 3.12 3.12 1 PMID:3972793 -3.5.1.3 * bacillus subtilis 10.9 5.745 2 PMID:4631108;PMID:4631109 -3.5.1.3 * homo sapiens 3.4 2.2 4 PMID:28358347 -3.5.1.3 * neurospora crassa 0.016 0.016 1 PMID:2857167 -3.5.1.3 * rattus norvegicus 570.0 30.035 6 PMID:19464248;PMID:3003502;PMID:5028495;PMID:5114531 -3.5.1.3 * thermus aquaticus 66.0 66.0 1 PMID:4631109 -3.5.1.30 * pseudomonas putida 130.0 130.0 1 PMID:5432799 -3.5.1.31 * euglena gracilis 2.68 2.68 1 PMID:5767026 -3.5.1.32 * campylobacter jejuni 120.0 120.0 1 PMID:16303789 -3.5.1.32 * fusarium incarnatum 7.4 7.4 1 * -3.5.1.32 * pseudomonas putida 426.0 426.0 1 * -3.5.1.35 * blastocladiella emersonii 0.004 0.004 1 * -3.5.1.36 * pseudomonas sp. 11.0 5.99 2 PMID:5470822;PMID:5808511 -3.5.1.38 * achromobacter sp. 190.0 190.0 1 PMID:5017769 -3.5.1.38 * acinetobacter glutaminasificans 150.0 150.0 1 PMID:6838661 -3.5.1.38 * citrobacter freundii 133.0 67.3 2 PMID:401650 -3.5.1.38 * delftia acidovorans 104.0 95.0 2 PMID:845119 -3.5.1.38 * pseudomonas sp. 160.0 130.0 2 PMID:5441;PMID:956189 -3.5.1.38 * rhodotorula toruloides 10510.0 6333.0 2 * -3.5.1.38 * streptomyces canarius 132.2 132.2 1 PMID:26691453 -3.5.1.38 * tilachlidium humicola 17.2 17.2 1 * -3.5.1.39 * ovis aries aries 0.12 0.12 1 PMID:5141674 -3.5.1.4 * achromobacter xylosoxidans 4.67 4.085 2 PMID:16002239 -3.5.1.4 * aeribacillus pallidus 221.0 37.5 3 PMID:17347819;PMID:23096998 -3.5.1.4 * alcaligenes sp. 0.011 0.008 3 PMID:15060035 -3.5.1.4 * brevibacterium sp. 274.1 9.0 9 PMID:7944367 -3.5.1.4 * burkholderia sp. 10.0 10.0 1 * -3.5.1.4 * cucurbita maxima 3.1e-05 2.95e-05 2 * -3.5.1.4 * delftia acidovorans 181.0 125.0 9 PMID:1141856;PMID:237757 -3.5.1.4 * escherichia coli 10000.0 12.2 11 PMID:3426369;PMID:7916690;PMID:9342349 -3.5.1.4 * geobacillus subterraneus 48.66 48.66 1 PMID:23708550 -3.5.1.4 * helicobacter pylori 65.0 11.0 13 PMID:9364923 -3.5.1.4 * klebsiella pneumoniae 2.69 2.69 1 PMID:8636044 -3.5.1.4 * paracoccus sp. (in: a-proteobacteria) 39.82 27.075 2 PMID:22101784 -3.5.1.4 * pseudomonas aeruginosa 4100.0 4.89 15 PMID:110589;PMID:2517478 -3.5.1.4 * pseudomonas chlororaphis 17.7 17.7 1 PMID:16534982 -3.5.1.4 * pseudomonas putida 1.89 0.039 13 * -3.5.1.4 * pseudomonas sp. 37.6 37.6 1 PMID:7944367 -3.5.1.4 * pseudonocardia thermophila 26.8 24.45 4 PMID:15103424 -3.5.1.4 * pyrococcus yayanosii 1430.0 571.5 4 PMID:24430467 -3.5.1.4 * rattus norvegicus 0.00074 0.00074 1 PMID:15492019 -3.5.1.4 * rhodococcus erythropolis 16.39 2.6999999999999997 8 PMID:8655547 -3.5.1.4 * rhodococcus rhodochrous 12.2 12.2 3 PMID:7916690;PMID:9342349 -3.5.1.4 * rhodococcus sp. (in: high g+c gram-positive bacteria) 7700.0 4250.0 6 PMID:17136368;PMID:1938876;PMID:7944367 -3.5.1.4 * saccharolobus solfataricus 16.0 0.85 4 PMID:16156792;PMID:18680459 -3.5.1.4 * streptococcus pneumoniae 20.0 20.0 1 PMID:3426369 -3.5.1.4 * streptomyces sp. 0.87 0.69 3 PMID:24752846 -3.5.1.4 * sulfurisphaera tokodaii 14.8 14.8 1 PMID:16125409 -3.5.1.4 * synthetic construct 6.87 2.0 4 PMID:38622797 -3.5.1.4 * xinfangfangia sp. dly26 30949.4 4905.1 11 PMID:33811594 -3.5.1.40 * fusarium anguioides 2.7 1.4200000000000002 2 PMID:4131159;PMID:50318 -3.5.1.41 * absidia caerulea 11.37 11.37 1 PMID:7608108 -3.5.1.41 * amylomyces rouxii 17.8 17.8 1 PMID:240696 -3.5.1.41 * aspergillus flavus 55.91 55.91 1 * -3.5.1.41 * aspergillus nidulans 25.0 25.0 1 PMID:7765883 -3.5.1.41 * bombyx mori 0.393 0.207 5 PMID:30682338 -3.5.1.41 * colletotrichum gloeosporioides 0.018 0.018 1 PMID:23688474 -3.5.1.41 * colletotrichum lindemuthianum 184.4 77.0 6 PMID:15555935;PMID:7592838;PMID:8987657 -3.5.1.41 * cunninghamella bertholletiae 0.075 0.075 1 PMID:15668816 -3.5.1.41 * cunninghamella echinulata 0.044 0.044 1 PMID:15668816 -3.5.1.41 * cunninghamella elegans 0.042 0.042 1 PMID:15668816 -3.5.1.41 * cunninghamella ramosa 0.018 0.018 1 PMID:15668816 -3.5.1.41 * euphausia superba 24.2 24.2 1 PMID:38396751 -3.5.1.41 * microbacterium esteraromaticum 137.54 137.54 1 PMID:35122801 -3.5.1.41 * mortierella sp. 175.0 89.0 2 PMID:21597184 -3.5.1.41 * mucor circinelloides 0.06 0.06 1 PMID:15668816 -3.5.1.41 * nitratireductor aquimarinus 50.43 50.43 1 PMID:32114175 -3.5.1.41 * penicillium oxalicum 55.38 55.38 3 * -3.5.1.41 * priestia aryabhattai 42.99 38.89 3 PMID:34917446 -3.5.1.41 * rhizopus circinans 965.1 965.1 1 PMID:18314348 -3.5.1.41 * rhizopus stolonifer 40.3 40.3 1 * -3.5.1.41 * saccharomyces cerevisiae 771.0 771.0 1 PMID:11812231 -3.5.1.41 * scopulariopsis brevicaulis 2.58 2.58 1 * -3.5.1.41 * streptomyces bacillaris 49.6 33.35 2 PMID:36615307 -3.5.1.41 * syncephalastrum racemosum 0.047 0.047 1 PMID:15668816 -3.5.1.42 * aspergillus niger 0.38 0.38 1 * -3.5.1.42 * azotobacter vinelandii 0.22 0.22 1 PMID:4144084 -3.5.1.42 * escherichia coli 2900.0 2900.0 1 PMID:7021549 -3.5.1.42 * shewanella oneidensis 1.8 0.9015 2 PMID:21953451 -3.5.1.42 * vibrio cholerae serotype o1 0.07 0.07 1 PMID:6119307 -3.5.1.43 * niallia circulans 303.0 205.3 3 PMID:1012012;PMID:4928623 -3.5.1.44 * chryseobacterium cucumeris 27.37 27.37 1 PMID:36016794 -3.5.1.44 * chryseobacterium proteolyticum 31.1 7.4 3 PMID:33740115 -3.5.1.44 * niallia circulans 367.1 78.0 3 PMID:1012012;PMID:4928623 -3.5.1.46 * arthrobacter sp. 4.16 4.16 1 PMID:16162506 -3.5.1.46 * flavobacterium sp. 1.4 1.225 2 * -3.5.1.46 * pseudomonas sp. 4.0 3.35 2 PMID:8515236 -3.5.1.47 * chlamydomonas reinhardtii 1e-05 1e-05 1 PMID:15652176 -3.5.1.47 * glycine max 1e-05 1e-05 1 PMID:15652176 -3.5.1.47 * nicotiana tabacum 1e-05 1e-05 1 PMID:15652176 -3.5.1.47 * priestia megaterium 80.0 70.0 2 PMID:4962540 -3.5.1.47 * zea mays 3e-05 3e-05 1 PMID:15652176 -3.5.1.48 * rattus sp. 0.54 0.54 1 PMID:28089;PMID:6621395 -3.5.1.49 * helicobacter pylori 1040.0 6.0 22 PMID:11359566;PMID:14742519 -3.5.1.49 * methylophilus methylotrophus 37.4 37.4 1 * -3.5.1.49 * paracoccidioides brasiliensis 2.73 1.79 3 PMID:15716068 -3.5.1.5 * arthrobacter mobilis 2370.0 2370.0 1 * -3.5.1.5 * aspergillus nidulans 670.0 670.0 1 * -3.5.1.5 * aspergillus niger 1341.0 1341.0 1 * -3.5.1.5 * bacterium strain sl100 1120.0 1120.0 1 PMID:9316997 -3.5.1.5 * bos taurus 59.9 59.9 1 PMID:18137 -3.5.1.5 * brucella suis 540.0 540.0 1 * -3.5.1.5 * brucella suis bv. 1 540.0 540.0 1 PMID:18638408 -3.5.1.5 * cajanus cajan 3120.0 3120.0 1 * -3.5.1.5 * canavalia ensiformis 8.82 8.82 1 PMID:23108614 -3.5.1.5 * coccidioides immitis 1750.0 1750.0 1 * -3.5.1.5 * corynebacterium ammoniagenes 3570.0 3535.0 2 * -3.5.1.5 * enterobacter sp. 109.0 105.35 2 PMID:18365149 -3.5.1.5 * glycine max 664.0 664.0 1 PMID:105010 -3.5.1.5 * helicobacter pylori 1700.0 1700.0 1 * -3.5.1.5 * klebsiella aerogenes 2500.0 1445.0 4 PMID:18823937 -3.5.1.5 * lathyrus oleraceus 5833.0 5833.0 1 PMID:25065975 -3.5.1.5 * limnospira maxima 9.27 9.27 1 * -3.5.1.5 * limosilactobacillus fermentum 220.0 110.3235 2 * -3.5.1.5 * limosilactobacillus reuteri 354.0 354.0 4 * -3.5.1.5 * lysinibacillus sphaericus 32.5 32.5 1 * -3.5.1.5 * momordica charantia 2.02 2.02 1 * -3.5.1.5 * mycobacterium tuberculosis 101.0 101.0 1 PMID:7559354 -3.5.1.5 * otala lactea 0.79 0.79 1 * -3.5.1.5 * proteus mirabilis 2000.0 2000.0 1 * -3.5.1.5 * providencia rettgeri 60.6 13.4 3 PMID:26627914;PMID:28197768 -3.5.1.5 * providencia stuartii 7100.0 7100.0 1 * -3.5.1.5 * pseudarthrobacter oxydans 219.0 219.0 1 * -3.5.1.5 * rhizopus arrhizus 112.0 112.0 1 * -3.5.1.5 * rhodobacter capsulatus 8.0 8.0 1 * -3.5.1.5 * schizosaccharomyces pombe 700.0 700.0 1 * -3.5.1.5 * selenomonas ruminantium 1100.0 1100.0 1 * -3.5.1.5 * sporosarcina pasteurii 2500.0 1748.25 2 PMID:3753142 -3.5.1.5 * staphylococcus leei 730.0 730.0 1 * -3.5.1.5 * staphylococcus saprophyticus 1979.0 1979.0 1 * -3.5.1.5 * staphylococcus xylosus 1573.0 1573.0 1 * -3.5.1.5 * streptococcus mitior 230.0 230.0 1 * -3.5.1.5 * streptococcus salivarius 1700.0 1700.0 1 PMID:8550211 -3.5.1.5 * ureaplasma urealyticum 180000.0 180000.0 1 * -3.5.1.5 * vicia sativa 45.0 45.0 1 PMID:38185304 -3.5.1.50 * cupriavidus necator 0.014 0.014 1 * -3.5.1.52 * aspergillus tubingensis 0.0538 0.0538 1 PMID:9312552 -3.5.1.52 * elizabethkingia meningoseptica 5.128 5.128 1 PMID:3110550 -3.5.1.52 * prunus amygdalus var. dulcis 0.0855 0.0623 3 PMID:7213757 -3.5.1.52 * sus scrofa 0.00275 0.00275 1 PMID:5669921 -3.5.1.53 * bacteroides thetaiotaomicron 11.6 11.6 1 PMID:37189741 -3.5.1.53 * rhodococcus sp. (in: high g+c gram-positive bacteria) 0.062 0.035 3 * -3.5.1.54 * chlamydomonas reinhardtii 19.3 19.3 1 * -3.5.1.54 * enterobacter cloacae 9.3 9.3 1 PMID:16597948 -3.5.1.54 * oleomonas sagaranensis 108.0 108.0 1 PMID:15796980 -3.5.1.54 * saccharomyces cerevisiae 7.65 7.65 1 PMID:4562164 -3.5.1.55 * brevundimonas diminuta 2933.0 2395.0 2 PMID:6501258;PMID:7096313 -3.5.1.55 * penicillium sp. 624.5 624.5 1 * -3.5.1.56 * alcaligenes sp. 26.25 26.25 1 * -3.5.1.56 * ochrobactrum sp. 0.481 0.481 1 PMID:16211382 -3.5.1.56 * pseudomonas sp. 1.98 1.98 1 PMID:3732281 -3.5.1.57 * arabidopsis sp. 17600.0 17600.0 1 * -3.5.1.57 * cutaneotrichosporon cutaneum 1110.0 1110.0 1 * -3.5.1.58 * enterococcus faecalis 0.0074 0.0037 4 * -3.5.1.59 * arthrobacter sp. 2.1 2.1 1 PMID:1381445 -3.5.1.59 * clostridium sp. 0.096 0.096 1 PMID:1510564 -3.5.1.59 * pseudomonas putida 0.958 0.958 1 PMID:3745168 -3.5.1.6 * arabidopsis sp. 0.03 0.03 1 PMID:11161056 -3.5.1.6 * blastobacter sp. 1.55e-05 1.55e-05 1 * -3.5.1.6 * burkholderia cepacia 8.67e-06 2.08e-06 9 * -3.5.1.6 * caenorhabditis elegans 1.1 1.1 1 PMID:20840592 -3.5.1.6 * canis lupus familiaris 0.074 0.074 1 PMID:13538975 -3.5.1.6 * comamonas sp. 3.12e-06 3.12e-06 1 * -3.5.1.6 * euglena gracilis 14.7 14.7 1 PMID:115499 -3.5.1.6 * homo sapiens 0.282 0.282 1 PMID:22525402 -3.5.1.6 * oryctolagus cuniculus 0.035 0.035 1 PMID:13538975 -3.5.1.6 * pigeon 0.084 0.084 1 PMID:13538975 -3.5.1.6 * pseudomonas putida 0.0009 0.0009 1 PMID:11759049 -3.5.1.6 * rattus norvegicus 0.88 0.88 1 PMID:10989448 -3.5.1.6 * rattus rattus 1.84 1.715 2 PMID:13538975;PMID:3678231 -3.5.1.6 * rhodobacter capsulatus 0.048 0.041 3 * -3.5.1.62 * micrococcus luteus 0.48 0.48 1 * -3.5.1.65 * pseudomonas aeruginosa 36.83 36.83 1 * -3.5.1.66 * arthrobacter sp. 3.79 3.79 1 PMID:3972793 -3.5.1.67 * arachis hypogaea 349.0 49.3 3 PMID:16667952;PMID:6863306 -3.5.1.68 * pseudomonas putida 380.0 240.0 2 PMID:3308850 -3.5.1.68 * rattus norvegicus 0.0192 0.0192 1 PMID:7612651 -3.5.1.69 * shewanella algae 30.4 30.4 1 PMID:11827965 -3.5.1.7 * faecalicatena orotica 7.4 7.4 1 PMID:14353892 -3.5.1.70 * actinoplanes utahensis 42.8 10.305 4 PMID:1398088;PMID:17586674;PMID:2760018 -3.5.1.71 * hordeum vulgare 0.022 0.022 1 * -3.5.1.73 * bacteria 328.0 328.0 1 PMID:7764422 -3.5.1.74 * phocaeicola vulgatus 24.45 8.15 8 PMID:2628421 -3.5.1.75 * bacillus licheniformis 0.041 0.041 1 PMID:7951136 -3.5.1.75 * candida parapsilosis 3.15 3.15 1 PMID:39151849 -3.5.1.75 * citrobacter sp. 0.254 0.254 1 PMID:2393957 -3.5.1.75 * metagenome 0.76 0.651 5 PMID:36591907;PMID:38948941 -3.5.1.75 * prescottella equi 6.0 6.0 1 PMID:16041575 -3.5.1.75 * providencia rettgeri 4.6 4.199999999999999 2 PMID:26627914;PMID:28197768 -3.5.1.76 * pseudomonas putida 6.25 6.25 1 PMID:1396711 -3.5.1.77 * agrobacterium sp. 30.0 30.0 1 * -3.5.1.77 * agrobacterium tumefaciens 10.1 10.1 1 PMID:8621596 -3.5.1.77 * comamonas sp. 0.34 0.34 1 PMID:8462543 -3.5.1.77 * crystallibacter crystallopoietes 0.84 0.84 1 PMID:29096146 -3.5.1.77 * ensifer adhaerens 21.4 15.325 2 PMID:16546310 -3.5.1.77 * nitratireductor indicus 2.68 2.68 1 PMID:36541894 -3.5.1.79 * xanthobacter agilis 9.0 7.65 2 * -3.5.1.8 * pseudomonas sp. 21000.0 13470.0 2 PMID:13449063 -3.5.1.81 * achromobacter denitrificans 204.0 204.0 1 PMID:23369306 -3.5.1.81 * achromobacter xylosoxidans 2023.0 1000.0 3 PMID:7763986;PMID:8541651;PMID:8776758 -3.5.1.81 * alcaligenes faecalis 580.0 580.0 1 PMID:16348465 -3.5.1.81 * pseudomonas sp. 40.6 40.6 1 PMID:699212 -3.5.1.81 * rhodococcus armeniensis 22.63 4.635 14 * -3.5.1.81 * streptomyces olivaceus 571.1 571.1 1 * -3.5.1.81 * streptomyces sp. 9.31 8.325 2 PMID:23264153 -3.5.1.81 * trichoderma sp. 42.1 42.1 1 * -3.5.1.81 * variovorax paradoxus 76.58 76.58 1 * -3.5.1.82 * achromobacter xylosoxidans 95.8 66.95 2 PMID:15338421 -3.5.1.82 * pseudomonas sp. 1100.0 844.5 2 PMID:1768127;PMID:1894006 -3.5.1.83 * achromobacter xylosoxidans 2506.0 1340.5 2 PMID:7763985 -3.5.1.84 * rhizobium leguminosarum bv. viciae 8.9 0.02 35 * -3.5.1.85 * prescottella equi 0.87 0.87 1 * -3.5.1.86 * alcaligenes faecalis 0.0268 0.0268 1 PMID:1660699 -3.5.1.87 * achromobacter xylosoxidans 1.22 1.22 1 PMID:8590654 -3.5.1.87 * brevibacillus reuszeri 145.0 145.0 1 PMID:23586522 -3.5.1.87 * geobacillus kaustophilus 10.0 6.455 2 * -3.5.1.87 * geobacillus stearothermophilus 221.4 103.485 8 PMID:20730754 -3.5.1.87 * paenarthrobacter aurescens 5.9 5.45 2 PMID:10194852;PMID:10681054 -3.5.1.87 * pseudomonas sp. 23.2 21.5 3 PMID:15300419;PMID:8829526 -3.5.1.87 * pseudomonas sp. on4a 23.2 23.2 1 PMID:19830420 -3.5.1.87 * sinorhizobium meliloti 0.66 0.66 1 PMID:16254442 -3.5.1.88 * borreliella burgdorferi 3.235 3.235 1 PMID:17977509 -3.5.1.88 * escherichia coli 1880.0 556.5 6 PMID:23357810;PMID:7896716;PMID:9610360;PMID:9665853 -3.5.1.88 * leptospira interrogans 780.6 780.6 1 PMID:12127977 -3.5.1.9 * bacillus cereus 5.9 5.9 1 PMID:14592712 -3.5.1.9 * bos taurus 425.0 425.0 1 PMID:1714804 -3.5.1.9 * cupriavidus metallidurans 3.5 3.5 1 PMID:14592712 -3.5.1.9 * drosophila melanogaster 0.48 0.37 2 PMID:50862 -3.5.1.9 * gallus gallus 80.4 80.4 1 PMID:4135584 -3.5.1.9 * mus musculus 42.0 0.0156 3 PMID:15866519;PMID:15935693 -3.5.1.9 * ogataea henricii 0.59 0.59 1 * -3.5.1.9 * oncorhynchus mykiss 1304.0 1304.0 1 PMID:1714804 -3.5.1.9 * pseudomonas aeruginosa 4.7 4.7 1 PMID:14592712 -3.5.1.9 * rattus sp. 346.0 162.9 4 PMID:4135014;PMID:4140137;PMID:4190298;PMID:84781 -3.5.1.9 * streptomyces coelicolor 3.0 3.0 1 PMID:22234533 -3.5.1.9 * streptomyces parvulus 26.8 17.565 2 PMID:2425918;PMID:2439878 -3.5.1.9 * sus scrofa 0.33 0.33 1 PMID:70225 -3.5.1.90 * cereibacter sphaeroides 0.07 0.045000000000000005 2 PMID:19889098 -3.5.1.90 * methanopyrus kandleri 0.027 0.014499999999999999 4 PMID:16740929 -3.5.1.90 * methanosarcina mazei 6.4 4.25 2 PMID:14990804 -3.5.1.91 * arthrobacter pascens 28.9 28.85 2 PMID:15358859;PMID:15721791 -3.5.1.92 * equus caballus 0.4 0.4 1 PMID:440106 -3.5.1.92 * sus scrofa 14.0 14.0 1 PMID:3517567;PMID:6885768 -3.5.1.93 * brevibacillus laterosporus 5.3 5.3 1 * -3.5.1.93 * brevundimonas diminuta 100.0 6.7 4 * -3.5.1.93 * pseudomonas sp. 133.0 11.600000000000001 8 PMID:1358202;PMID:16151116;PMID:18586517 -3.5.1.93 * pseudomonas sp. 130 13.0 12.5 2 PMID:15200051;PMID:9518465 -3.5.1.97 * bacillus thuringiensis serovar kyushuensis 2.995 2.995 1 PMID:20492673 -3.5.1.97 * ochrobactrum quorumnocens 19.2 19.2 1 PMID:30712466 -3.5.1.97 * pseudomonas syringae 3800.0 0.0408 9 PMID:18997027 -3.5.1.98 * arachis hypogaea 54.1 37.55 2 PMID:26217363 -3.5.1.99 * homo sapiens 0.0213 0.015189999999999999 2 PMID:29408178 -3.5.2.10 * pseudomonas putida 1560.0 429.0 4 PMID:20043918;PMID:500580 -3.5.2.10 * pseudomonas sp. 100.0 100.0 1 * -3.5.2.12 * acidovorax sp. t31 8.26 5.515 2 PMID:19420719 -3.5.2.12 * cupriavidus sp. t7 1.22 1.22 1 PMID:19420719 -3.5.2.12 * cupriavidus sp. u124 1.29 1.29 1 PMID:19420719 -3.5.2.12 * flavobacterium sp. 0.02 0.02 1 * -3.5.2.12 * paenarthrobacter ureafaciens 4.1 4.1 1 PMID:19889645 -3.5.2.12 * pseudomonas sp. 0.004 0.004 1 PMID:8515236 -3.5.2.12 * rhodococcus sp. u-224 6.54 3.45 2 PMID:18685217;PMID:19420719 -3.5.2.12 * sphingomonas sp. u238 0.29 0.29 1 PMID:19420719 -3.5.2.15 * pseudomonas sp. 109.5 109.5 1 PMID:10427042 -3.5.2.16 * blastobacter sp. a17p-4 927.0 927.0 1 PMID:9030755 -3.5.2.16 * oreochromis niloticus 122.0 122.0 1 PMID:14637160 -3.5.2.16 * rattus norvegicus 27.0 27.0 1 PMID:8388376 -3.5.2.16 * sus scrofa 13.3 13.3 1 PMID:10873544 -3.5.2.17 * glycine max 10.0 10.0 1 PMID:10567345 -3.5.2.17 * herbaspirillum seropedicae 37650.0 37650.0 1 PMID:19632197 -3.5.2.2 * agrobacterium rubi 1.14 0.7194999999999999 2 * -3.5.2.2 * agrobacterium sp. 11.3 0.033 3 * -3.5.2.2 * agrobacterium tumefaciens 103.6 0.112 21 PMID:12821331;PMID:16920364;PMID:7488185 -3.5.2.2 * bacillus sp. (in: firmicutes) 3.6 0.62 13 PMID:16284925 -3.5.2.2 * bos taurus 66.2 11.7 4 PMID:13428761;PMID:2827580;PMID:6639068 -3.5.2.2 * brevibacillus agri 5.79 5.79 1 * -3.5.2.2 * crystallibacter crystallopoietes 216.0 100.0 3 * -3.5.2.2 * ensifer adhaerens 1.591 0.385 13 * -3.5.2.2 * geobacillus stearothermophilus 148.6 148.6 1 PMID:9170256 -3.5.2.2 * geobacillus thermocatenulatus 461.0 96.55 6 PMID:15304782 -3.5.2.2 * microbacterium maritypicum 0.37 0.22 2 PMID:16116274 -3.5.2.2 * niallia circulans 43.8 43.8 1 PMID:9170254 -3.5.2.2 * paenarthrobacter aurescens 76.6 12.0 13 PMID:9650283 -3.5.2.2 * pseudomonas aeruginosa 5.8 0.865 8 PMID:25993634 -3.5.2.2 * pseudomonas fluorescens 20.9 0.192 26 PMID:26821258;PMID:3101721 -3.5.2.2 * pseudomonas putida 600.8 1.9 19 PMID:11759049;PMID:17124633;PMID:18556813 -3.5.2.2 * ralstonia pickettii 0.00113 0.00113 1 PMID:12837777 -3.5.2.2 * rattus norvegicus 14.8 14.8 1 PMID:8307005 -3.5.2.2 * sus scrofa 1.06 1.06 1 PMID:8494893 -3.5.2.2 * thermus sp. 136.8 136.8 1 PMID:10681055 -3.5.2.20 * bradyrhizobium japonicum 0.611 0.41 3 * -3.5.2.20 * mesorhizobium loti 0.64 0.64 1 * -3.5.2.20 * neorhizobium galegae 0.69 0.69 1 * -3.5.2.3 * cricetinae 2.66 2.66 1 PMID:29210 -3.5.2.3 * escherichia coli 371.0 324.5 2 PMID:2871020;PMID:6142052 -3.5.2.3 * faecalicatena orotica 155.0 77.516 2 PMID:2864918;PMID:8424 -3.5.2.3 * klebsiella pneumoniae 22.79 14.46 5 PMID:20676924 -3.5.2.3 * plasmodium falciparum 0.4985 0.24995 2 PMID:18082626 -3.5.2.3 * pseudomonas putida 68.0 43.0 2 PMID:8572888 -3.5.2.3 * staphylococcus aureus 0.68 0.68 1 PMID:23246866 -3.5.2.3 * toxoplasma gondii 18.4 18.33 3 PMID:16621066 -3.5.2.5 * aquarana catesbeiana 0.5 0.29 2 PMID:11791734 -3.5.2.5 * arabidopsis thaliana 10.0 5.5 2 PMID:14976234 -3.5.2.5 * chlamydomonas reinhardtii 39.8 39.8 1 * -3.5.2.5 * escherichia coli 410.0 42.05 6 PMID:12486048;PMID:21739308 -3.5.2.5 * glycine max 0.037 0.037 1 PMID:8290630 -3.5.2.5 * lathyrus sativus 0.006 0.006 1 * -3.5.2.5 * lithobates pipiens 0.03 0.016 2 PMID:3081517;PMID:6833275;PMID:7765882 -3.5.2.5 * metabacillus fastidiosus 0.002 0.002 1 PMID:3081517;PMID:7765882 -3.5.2.5 * phaseolus vulgaris 563.0 347.5 4 PMID:18251875 -3.5.2.5 * pseudomonas aeruginosa 0.99 0.525 2 PMID:6814497;PMID:828028 -3.5.2.5 * robinia pseudoacacia 5.0 5.0 1 PMID:14976234 -3.5.2.6 * [haemophilus] ducreyi 2475.0 2475.0 1 PMID:11570857 -3.5.2.6 * acinetobacter baylyi 0.0216 0.0216 1 PMID:17403709 -3.5.2.6 * acinetobacter bereziniae 12.5 12.5 1 PMID:22508298 -3.5.2.6 * acinetobacter pittii 0.159 0.159 1 PMID:15047547 -3.5.2.6 * aeromonas sobria 110.0 110.0 1 PMID:9182099 -3.5.2.6 * bacillus anthracis 19000.0 19000.0 1 PMID:21369909 -3.5.2.6 * bacillus cereus 5617.0 5617.0 1 PMID:166286 -3.5.2.6 * bacillus licheniformis 5917.0 5542.0 4 PMID:6471 -3.5.2.6 * bacteroides fragilis 260.0 240.0 3 PMID:9126607 -3.5.2.6 * citrobacter freundii 388.0 388.0 1 PMID:6973612 -3.5.2.6 * elizabethkingia meningoseptica 110.0 110.0 1 PMID:9182099 -3.5.2.6 * enterobacter cloacae 2240.0 134.3 3 PMID:16189133;PMID:4731970;PMID:8807798 -3.5.2.6 * enterobacter sp. 5667.0 5667.0 1 PMID:1169676 -3.5.2.6 * escherichia coli 1296.0 250.0 5 PMID:4564055 -3.5.2.6 * fusobacterium nucleatum 4.8 4.8 1 PMID:16870757 -3.5.2.6 * janthinobacterium lividum 20.5 20.5 1 PMID:15561856 -3.5.2.6 * klebsiella aerogenes 163.0 163.0 1 PMID:4731970 -3.5.2.6 * moraxella catarrhalis 75.8 75.8 1 PMID:1396750 -3.5.2.6 * morganella morganii 190.0 190.0 1 PMID:70426 -3.5.2.6 * neisseria gonorrhoeae 13.67 7.015 2 PMID:17061490 -3.5.2.6 * pseudomonas aeruginosa 264.0 75.5 3 PMID:15155197;PMID:235307;PMID:6799477 -3.5.2.6 * pseudomonas putida 46200.0 23100.0231 2 PMID:18757180 -3.5.2.6 * psychrobacter immobilis 2094.0 2094.0 1 PMID:9063463 -3.5.2.6 * serratia fonticola 1650.0 1650.0 1 PMID:9300809 -3.5.2.6 * staphylococcus aureus 5250.0 252.0 5 PMID:1134376;PMID:1605608 -3.5.2.6 * streptomyces albus 33.0 33.0 1 PMID:1134377 -3.5.2.6 * streptomyces cacaoi 2430.0 2430.0 1 PMID:6970744 -3.5.2.6 * streptomyces sp. 980.0 589.0 2 PMID:1134377;PMID:309466 -3.5.2.7 * bacillus subtilis 0.12 0.12 1 * -3.5.2.7 * rattus norvegicus 1.54 1.54 1 * -3.5.2.9 * bos taurus 0.625 0.313475 2 PMID:14993790 -3.5.2.9 * paecilomyces variotii 0.69 0.69 1 PMID:10460889 -3.5.2.9 * pseudomonas putida 243.0 159.0 4 PMID:3911007;PMID:6145710 -3.5.2.9 * pseudomonas sp. 3.4 3.4 1 PMID:4823446 -3.5.2.9 * rattus norvegicus 87.0 3.0 13 PMID:1181279;PMID:1181280;PMID:18584486;PMID:239948;PMID:3911006;PMID:7096358;PMID:938527 -3.5.2.9 * sus scrofa 3.6 3.6 1 PMID:10078874 -3.5.2.9 * triticum aestivum 20.1 20.1 1 PMID:16660609 -3.5.3.1 * bacillus brevis nagano 414.0 414.0 1 PMID:9244379 -3.5.3.1 * bacillus brevis tt02-8 4746.0 4746.0 1 PMID:7765033 -3.5.3.1 * bacillus subtilis 0.15 0.088 2 PMID:23625224 -3.5.3.1 * bison bison 11.5 11.5 1 PMID:27468469 -3.5.3.1 * bos taurus 91300.0 45652.9 2 PMID:16094464;PMID:5023576 -3.5.3.1 * clarias batrachus 40.0 40.0 1 PMID:1705780 -3.5.3.1 * coriandrum sativum 81.728 81.728 1 PMID:29944940 -3.5.3.1 * geobacillus thermodenitrificans 138.3 138.3 1 PMID:25908562 -3.5.3.1 * glycine max 90.0 90.0 1 PMID:16667583 -3.5.3.1 * heteropneustes fossilis 0.694 0.43899999999999995 2 PMID:23195132 -3.5.3.1 * homo sapiens 1600.0 400.0 5 PMID:19138817;PMID:19374748;PMID:19636440;PMID:21945700 -3.5.3.1 * leishmania amazonensis 1140.0 586.5 2 PMID:18400316 -3.5.3.1 * mus booduga 1249.0 1249.0 1 PMID:9502047 -3.5.3.1 * mus musculus 41.5 0.0031675 8 PMID:14712329;PMID:19021765 -3.5.3.1 * penicillium chrysogenum 24.45 13.445 2 PMID:25322968 -3.5.3.1 * rattus norvegicus 562.0 30.8 5 PMID:14712329;PMID:6825701 -3.5.3.1 * rhodobacter capsulatus 183.0 183.0 1 PMID:1541268 -3.5.3.1 * saccharomyces cerevisiae 885.0 885.0 1 PMID:2404017 -3.5.3.1 * schistosoma mansoni 669.0 669.0 1 PMID:18723022 -3.5.3.1 * vigna catjang 2045.0 2045.0 1 PMID:16094464 -3.5.3.10 * arthrobacter sp. 8.71 8.71 1 PMID:12761196 -3.5.3.11 * methanocaldococcus jannaschii 0.45 0.45 1 PMID:22439800 -3.5.3.12 * arabidopsis thaliana 26.4 26.4 1 PMID:12782327 -3.5.3.12 * arachis hypogaea 0.135 0.135 1 * -3.5.3.12 * cucumis sativus 14.5 8.57 2 PMID:12821325 -3.5.3.12 * enterococcus faecalis 16.7 11.3 2 * -3.5.3.12 * evernia prunastri 205.5 205.5 1 * -3.5.3.12 * glycine max 172.2 172.2 1 PMID:1989611 -3.5.3.12 * lathyrus sativus 1.1 1.1 1 PMID:6895223 -3.5.3.12 * oryza sativa 47.31 47.31 1 * -3.5.3.12 * pseudomonas aeruginosa pa14 0.015 0.012775 2 PMID:20149107 -3.5.3.12 * streptococcus criceti 0.0109 0.0109 1 PMID:19121075 -3.5.3.12 * streptococcus downei 0.006 0.006 1 PMID:19121075 -3.5.3.12 * streptococcus mutans 0.4762 0.124 4 PMID:19121075 -3.5.3.12 * streptococcus ratti 0.102 0.033 10 PMID:19121075 -3.5.3.12 * streptococcus sobrinus 0.016 0.01285 2 PMID:19121075 -3.5.3.12 * zea mays 876.3 16.1075 4 PMID:11314948;PMID:16661738 -3.5.3.13 * pseudomonas aeruginosa 12.8 12.75 2 PMID:5012325 -3.5.3.13 * pseudomonas putida 0.093 0.06 9 PMID:3308850 -3.5.3.14 * pseudomonas chlororaphis 27.9 18.814999999999998 2 PMID:4651648 -3.5.3.15 * aspergillus nidulans 46.5 46.5 1 PMID:30797478 -3.5.3.15 * aspergillus nidulans var. dentatus 26.6 26.6 1 PMID:30797478 -3.5.3.15 * bos taurus 59.0 1.28 3 PMID:20224908;PMID:6860676;PMID:7689646 -3.5.3.15 * homo sapiens 0.583 0.5085 2 PMID:16091842 -3.5.3.15 * mus musculus 10.14 9.295 2 PMID:17716614;PMID:7872804 -3.5.3.15 * porphyromonas gingivalis 0.0334 0.0334 1 PMID:10377098 -3.5.3.15 * rattus norvegicus 0.793 0.39688500000000004 2 PMID:7217033;PMID:9192727 -3.5.3.16 * alcaligenes sp. 102.0 102.0 1 PMID:7353662 -3.5.3.18 * bos taurus 0.55 0.55 1 PMID:11546769 -3.5.3.18 * mus musculus 1.6 1.1 3 PMID:18567702 -3.5.3.2 * corynebacterium sp. 25.8 25.8 1 * -3.5.3.2 * flavobacterium sp. 190.0 190.0 1 * -3.5.3.2 * pseudomonas putida 0.39 0.39 1 * -3.5.3.2 * pseudomonas sp. 63.7 63.7 1 * -3.5.3.23 * escherichia coli 5.3 5.3 1 PMID:15703173 -3.5.3.3 * alcaligenes faecalis 14.0 14.0 1 PMID:33069232 -3.5.3.3 * alcaligenes sp. 8.5 8.5 1 PMID:3742654 -3.5.3.3 * glutamicibacter nicotianae 124.4 0.0203 3 PMID:25536878 -3.5.3.3 * paracoccus sp. wb1 6.1 6.1 1 * -3.5.3.3 * pseudomonas putida 26.54 13.334 2 PMID:1015832;PMID:29090065 -3.5.3.4 * chlamydomonas reinhardtii 185.0 185.0 1 PMID:10860551 -3.5.3.4 * pseudomonas aeruginosa 177.0 91.95 2 PMID:4989534;PMID:6030341 -3.5.3.5 * pseudomonas sp. 10.8 10.8 1 PMID:13449062 -3.5.3.6 * aspergillus fumigatus 26.7 21.5 3 PMID:25582958 -3.5.3.6 * aspergillus nidulans 12.9 12.9 1 PMID:31615671 -3.5.3.6 * enterococcus faecalis 131.2 131.2 1 PMID:30047723 -3.5.3.6 * enterococcus faecium 76.65 76.65 1 PMID:26363115 -3.5.3.6 * giardia duodenalis 41.0 36.5 3 PMID:18179862;PMID:9468500 -3.5.3.6 * halobacterium salinarum 5.4 5.4 1 PMID:18179862 -3.5.3.6 * halothermothrix orenii 91.8 91.8 1 PMID:35761421 -3.5.3.6 * homo sapiens 50.0 50.0 1 PMID:17982619 -3.5.3.6 * lactococcus lactis ssp. lactis 140.3 140.3 1 PMID:18179862 -3.5.3.6 * lactococcus lactis subsp. lactis 140.3 140.3 1 PMID:17223359 -3.5.3.6 * metamycoplasma arthritidis 27.0 27.0 1 PMID:17105223 -3.5.3.6 * metamycoplasma hominis 35.0 35.0 1 PMID:18179862 -3.5.3.6 * metapseudomonas furukawaii 29.559 29.559 1 PMID:31326652 -3.5.3.6 * mycoplasmopsis arginini 44.5 33.150000000000006 4 PMID:18179862;PMID:7765234 -3.5.3.6 * porphyromonas gingivalis 0.175 0.0876725 2 PMID:19545534 -3.5.3.6 * pseudomonas plecoglossicida 4.76 2.618 2 PMID:18179862;PMID:19280262 -3.5.3.6 * pseudomonas putida 70.3 58.8 3 PMID:11946203;PMID:18179862;PMID:30143336 -3.5.3.6 * streptococcus pyogenes 1.5 1.5 1 PMID:23867361 -3.5.3.6 * streptococcus sanguinis 0.115 0.115 1 PMID:18179862 -3.5.3.7 * arthrobacter sp. 8.71 8.71 1 PMID:12761196 -3.5.3.7 * aspergillus niger 68.0 68.0 1 PMID:30806615 -3.5.3.7 * brevibacterium helvolum 83.8 48.4 2 PMID:7766193 -3.5.3.7 * pseudomonas aeruginosa 910.0 135.7 3 PMID:12029055 -3.5.3.7 * pseudomonas putida 303.0 178.0 8 PMID:5043851 -3.5.3.7 * pseudomonas sp. 287.0 269.5 2 * -3.5.3.8 * bacillus subtilis 4.3 4.3 1 PMID:4990470 -3.5.3.8 * klebsiella aerogenes 0.028 0.028 1 PMID:5845833 -3.5.3.8 * pseudomonas putida 100.0 100.0 1 PMID:3308850 -3.5.3.9 * metabacillus fastidiosus 7.271 7.271 1 PMID:7503567 -3.5.3.9 * phaseolus vulgaris 1.0 0.1834 8 PMID:15627697;PMID:17594111 -3.5.4.1 * aspergillus fumigatus 2.3 2.3 1 * -3.5.4.1 * aspergillus niger 844.93 844.93 1 PMID:36627557 -3.5.4.1 * bacillus subtilis 0.1 0.1 1 * -3.5.4.1 * burkholderia cepacia 2.7 1.0 3 * -3.5.4.1 * citrobacter freundii 0.32 0.29000000000000004 2 * -3.5.4.1 * enterobacter cloacae 0.1 0.1 1 * -3.5.4.1 * escherichia coli 144.0 12.0 29 PMID:18517259;PMID:8226944 -3.5.4.1 * klebsiella aerogenes 0.52 0.52 1 * -3.5.4.1 * micrococcus flavus 0.1 0.1 1 * -3.5.4.1 * proteus vulgaris 0.14 0.14 1 * -3.5.4.1 * pseudomonas aeruginosa 0.6 0.6 1 * -3.5.4.1 * pseudomonas chlororaphis subsp. aureofaciens 0.58 0.58 1 * -3.5.4.1 * pseudomonas coronafaciens pv. striafaciens 0.31 0.20500000000000002 2 * -3.5.4.1 * pseudomonas fluorescens 0.19 0.19 1 * -3.5.4.1 * pseudomonas fragi 0.1 0.1 1 * -3.5.4.1 * pseudomonas putida 0.23 0.165 2 * -3.5.4.1 * pseudomonas schuylkilliensis 0.22 0.22 1 * -3.5.4.1 * pseudomonas sp. 'cruciviae' 0.41 0.41 1 * -3.5.4.1 * pseudomonas taetrolens 0.1 0.1 1 * -3.5.4.1 * pseudomonas trifolii 0.22 0.22 1 * -3.5.4.1 * salmonella enterica subsp. enterica serovar typhimurium 21.4 19.2 2 PMID:3000814;PMID:6758859 -3.5.4.1 * serratia marcescens 1.2 0.82 2 * -3.5.4.1 * serratia polymuthicum 0.1 0.1 1 * -3.5.4.10 * gallus gallus 5.09 5.09 1 PMID:7470484 -3.5.4.10 * methanothermobacter thermautotrophicus 1.8 1.8 1 PMID:17407260 -3.5.4.11 * priestia megaterium 0.017 0.017 1 PMID:34599 -3.5.4.12 * bacillus subtilis 6.36 6.36 1 PMID:418064 -3.5.4.12 * cricetinae 0.37 0.37 1 PMID:4455201 -3.5.4.12 * equus asinus 820.0 725.0 4 PMID:101672;PMID:1898061;PMID:7120402 -3.5.4.12 * escherichia phage t2 430.0 430.0 1 PMID:357901;PMID:4621659 -3.5.4.12 * homo sapiens 500.0 481.0 3 PMID:2247612;PMID:7240207;PMID:8448179 -3.5.4.12 * lactobacillus acidophilus 0.03 0.03 1 PMID:5002683 -3.5.4.12 * tequatrovirus t4 220.0 220.0 1 PMID:10777550 -3.5.4.13 * bacillus subtilis 41.4 41.4 1 PMID:4976547 -3.5.4.13 * salmonella enterica subsp. enterica serovar typhimurium 0.98 0.98 1 PMID:234434;PMID:357902 -3.5.4.15 * camellia sinensis 143.0 143.0 1 * -3.5.4.15 * rattus norvegicus 62.4 62.4 1 PMID:226661 -3.5.4.16 * bacillus subtilis 173.0 173.0 1 PMID:7887891 -3.5.4.16 * escherichia coli 0.091 0.0895 2 PMID:12559918 -3.5.4.16 * nocardia iowensis 6.0 0.00027 5 PMID:15135390 -3.5.4.16 * rattus norvegicus 510.0 510.0 1 PMID:9092499 -3.5.4.16 * serratia indica 67.0 67.0 1 * -3.5.4.16 * streptomyces tubercidicus 9.1 9.1 1 PMID:9868539 -3.5.4.17 * desulfovibrio desulfuricans 26.4 26.4 1 PMID:5773435 -3.5.4.17 * meretrix lusoria 3.77 3.77 1 * -3.5.4.17 * todarodes pacificus 76.3 76.3 1 * -3.5.4.17 * turbo cornutus 126.0 126.0 1 * -3.5.4.18 * microsporum audouinii 45.0 45.0 1 PMID:6048966 -3.5.4.19 * methanococcus vannielii 17.6 17.6 1 PMID:9931020 -3.5.4.19 * neurospora crassa 12.0 12.0 1 PMID:4309307 -3.5.4.19 * saccharomyces cerevisiae 903.0 903.0 1 PMID:379004 -3.5.4.2 * azotobacter vinelandii 3.8 3.8 1 * -3.5.4.2 * blastobotrys adeninivorans 1.88 1.88 1 PMID:23902582 -3.5.4.2 * crithidia fasciculata 0.71 0.39049999999999996 2 PMID:20850;PMID:291031 -3.5.4.2 * escherichia coli 5.97 5.97 1 PMID:11440125 -3.5.4.2 * leishmania braziliensis 0.012 0.012 1 PMID:291031 -3.5.4.2 * leishmania donovani 0.64 0.64 1 PMID:291031 -3.5.4.2 * leishmania mexicana 0.22 0.22 1 PMID:291031 -3.5.4.2 * leishmania tarentolae 0.58 0.58 1 PMID:291031 -3.5.4.2 * methanocaldococcus jannaschii 5.8 5.3 3 PMID:26990095 -3.5.4.2 * saccharomyces cerevisiae 8.34 4.177 2 PMID:1577682;PMID:18673302 -3.5.4.21 * corynebacterium glutamicum 34.0 34.0 1 * -3.5.4.21 * escherichia coli 0.0216 0.00225 4 * -3.5.4.21 * flavobacterium filamentosum 39.8 39.8 1 PMID:3980459 -3.5.4.21 * paenarthrobacter ureafaciens 296.0 296.0 1 * -3.5.4.21 * proteus mirabilis 0.0062 0.00335 4 * -3.5.4.21 * pseudomonas chlororaphis 0.0112 0.00785 4 * -3.5.4.21 * pseudomonas chlororaphis subsp. aureofaciens 0.01 0.00355 4 * -3.5.4.21 * pseudomonas putida 0.0014 0.0008500000000000001 4 * -3.5.4.21 * pseudomonas putida 77 0.089 0.013500000000000002 8 * -3.5.4.21 * pseudomonas sp. 0.33 0.33 1 * -3.5.4.21 * pseudomonas sp. 'cruciviae' 0.0014 0.0009 2 * -3.5.4.21 * pseudomonas sp. 0114 0.0013 0.000815 4 * -3.5.4.21 * pseudomonas sp. h21 0.0067 0.0013 5 * -3.5.4.21 * uncultured bacterium 78.0 78.0 1 PMID:1819465 -3.5.4.22 * pseudomonas putida 4.78 4.78 1 PMID:5845838 -3.5.4.23 * aspergillus terreus 220.5 220.5 1 PMID:236272 -3.5.4.24 * bombyx mori 178.8 90.47500000000001 2 PMID:5572808 -3.5.4.25 * arabidopsis thaliana 165.0 109.0 2 PMID:10783978 -3.5.4.25 * escherichia coli 0.223 0.038 7 PMID:12392559;PMID:235552 -3.5.4.25 * streptomyces coelicolor 0.08 0.08 1 PMID:17002314 -3.5.4.27 * archaeoglobus fulgidus 1765.0 1765.0 1 PMID:8481088 -3.5.4.27 * archaeoglobus lithotrophicus 1.6 1.6 1 * -3.5.4.27 * archaeoglobus profundus 0.029 0.029 1 * -3.5.4.27 * ferroglobus placidus 10.0 10.0 1 PMID:9000337 -3.5.4.27 * methanopyrus kandleri 5410.0 5026.0 3 PMID:11265475;PMID:9676239 -3.5.4.27 * methanosarcina barkeri 470.0 470.0 1 PMID:2298699 -3.5.4.27 * methylorubrum extorquens 630.0 367.0 2 PMID:10215859 -3.5.4.28 * streptomyces albus 15.4 15.4 1 PMID:2592350 -3.5.4.29 * methanocaldococcus jannaschii 0.39 0.39 1 PMID:12475257 -3.5.4.3 * blastobotrys adeninivorans 4.7 2.4 2 PMID:24481069 -3.5.4.3 * camellia sinensis 48.8 48.8 1 * -3.5.4.3 * drosophila melanogaster 0.6435 0.321805 2 PMID:19567870 -3.5.4.3 * halobacterium salinarum 530.0 530.0 1 PMID:9457844 -3.5.4.3 * haloferax volcanii 1140.0 1140.0 1 PMID:9457844 -3.5.4.3 * homo sapiens 22.1 21.5 5 PMID:10075721;PMID:3966794;PMID:546144 -3.5.4.3 * mus musculus 5.1 3.76 2 PMID:4643694 -3.5.4.3 * oryctolagus cuniculus 25.4 18.25 8 PMID:239400;PMID:4857982;PMID:6713831;PMID:692399 -3.5.4.3 * rattus norvegicus 33.6 13.2 7 PMID:4643694;PMID:7040358 -3.5.4.30 * methanocaldococcus jannaschii 10.5 10.5 1 PMID:12538648 -3.5.4.37 * xenopus laevis 0.002 0.002 1 PMID:8144588 -3.5.4.4 * arabidopsis thaliana 0.12 0.12 1 PMID:18673302 -3.5.4.4 * argopecten irradians concentricus 180.0 180.0 1 * -3.5.4.4 * azotobacter vinelandii 5.0 5.0 1 PMID:7212927 -3.5.4.4 * bacillus cereus 102.0 102.0 1 PMID:3096380 -3.5.4.4 * biomphalaria glabrata 2029.0 1431.5 2 PMID:16097741 -3.5.4.4 * bos taurus 400.0 1.0 19 PMID:16929383;PMID:18188767;PMID:18343902;PMID:19361992;PMID:5127384 -3.5.4.4 * camelus dromedarius 25.87 25.87 1 PMID:12379282 -3.5.4.4 * escherichia coli 277.0 277.0 1 PMID:357905 -3.5.4.4 * fasciola gigantica 62.7 33.550000000000004 2 PMID:18436213 -3.5.4.4 * gallus gallus 20.0 20.0 1 PMID:12381379 -3.5.4.4 * halobacterium salinarum 760.0 760.0 1 PMID:9457844 -3.5.4.4 * haloferax volcanii 120.0 120.0 1 PMID:9457844 -3.5.4.4 * homo sapiens 1200.0 0.4625 36 PMID:12381379;PMID:15926889;PMID:16542154;PMID:16929383;PMID:1705781;PMID:18680557;PMID:3606997;PMID:409634;PMID:4625871;PMID:4721618;PMID:6975278;PMID:9388 -3.5.4.4 * hyalomma dromedarii 150.8 2.075 4 PMID:17089216 -3.5.4.4 * kitasatospora aureofaciens 5300.0 5300.0 1 * -3.5.4.4 * klebsiella sp. 782.0 782.0 1 * -3.5.4.4 * kocuria rosea 3.04 1.703 2 PMID:1168529 -3.5.4.4 * macrococcoides caseolyticum 0.16 0.118 2 PMID:1168529 -3.5.4.4 * micrococcus candidus 10.5 5.3905 2 PMID:1168529 -3.5.4.4 * micrococcus freudenreichii 19.1 10.190000000000001 2 PMID:1168529 -3.5.4.4 * micrococcus luteus 9.07 3.346 4 PMID:1168529 -3.5.4.4 * micrococcus sodonensis 2180.0 1276.0 2 PMID:1168529 -3.5.4.4 * micrococcus sp. 0.136 0.093 2 PMID:1168529 -3.5.4.4 * mus musculus 30.18 30.18 1 PMID:10718633 -3.5.4.4 * nocardioides sp. 4677.0 4677.0 1 PMID:7986382 -3.5.4.4 * plasmodium falciparum 0.003 0.003 1 PMID:6363411 -3.5.4.4 * pseudomonas iodinum 271.0 271.0 1 PMID:624400 -3.5.4.4 * rattus norvegicus 4400.0 2216.0 3 PMID:1705781;PMID:6815190 -3.5.4.4 * staphylococcus aerogenes 0.191 0.191 1 PMID:1168529 -3.5.4.4 * staphylococcus aureus 0.401 0.401 1 PMID:1168529 -3.5.4.4 * streptomyces sp. 211.0 211.0 1 * -3.5.4.4 * sus scrofa 34.2 34.2 1 PMID:7159417 -3.5.4.4 * xenopus laevis 0.12 0.12 1 PMID:8144588 -3.5.4.42 * leucobacter triazinivorans 11.2 11.2 1 PMID:33158617 -3.5.4.42 * pseudomonas sp. 16.2 16.2 1 PMID:12218024 -3.5.4.43 * pseudomonas sp. 1.05 1.05 1 PMID:17660279 -3.5.4.45 * paracidovorax citrulli 0.245 0.07600000000000001 4 PMID:11274097 -3.5.4.5 * arabidopsis thaliana 74.0 74.0 1 PMID:10024464 -3.5.4.5 * bacillus subtilis 238.0 238.0 1 PMID:10493793 -3.5.4.5 * escherichia coli 3558.0 43.0 13 PMID:10493793;PMID:357900;PMID:4202859;PMID:6386817 -3.5.4.5 * homo sapiens 738.0 3.96 11 PMID:1318170;PMID:18600531;PMID:1929398;PMID:8297652;PMID:8494545;PMID:8812871;PMID:9598147 -3.5.4.5 * mus musculus 90.0 46.65 2 PMID:623754;PMID:692393 -3.5.4.5 * mycobacterium tuberculosis 5.44 3.605 6 PMID:20035876 -3.5.4.5 * nocardioides sp. 225.0 225.0 1 PMID:12353623 -3.5.4.5 * saccharomyces cerevisiae 3.128 3.128 1 PMID:357899 -3.5.4.6 * canis lupus familiaris 1.12 1.12 1 * -3.5.4.6 * gallus gallus 976.0 976.0 1 PMID:102336 -3.5.4.6 * helix pomatia 550.0 337.5 2 PMID:37471401 -3.5.4.6 * homo sapiens 1850.0 0.056999999999999995 8 PMID:1627354;PMID:18493842;PMID:20207414;PMID:4828847;PMID:9857047 -3.5.4.6 * oncorhynchus mykiss 0.18 0.18 1 PMID:1790670 -3.5.4.6 * oryctolagus cuniculus 1100.0 1000.0 2 PMID:11341922;PMID:12535614;PMID:7639701 -3.5.4.6 * raja clavata 2743.0 2743.0 1 * -3.5.4.6 * saccharomyces cerevisiae 343.3 343.3 1 PMID:39610 -3.5.4.6 * schizosaccharomyces pombe 67.0 67.0 1 PMID:8440738 -3.5.4.6 * sciaena umbra 1000.0 1000.0 1 * -3.5.4.6 * scorpaena porcus 1000.0 1000.0 1 * -3.5.4.6 * scyliorhinus canicula 711.0 711.0 1 * -3.5.4.7 * aspergillus melleus 6.0 6.0 1 * -3.5.4.7 * aspergillus ochraceus 2.5 2.5 1 * -3.5.4.8 * clostridium cylindrosporum 140.0 140.0 1 PMID:13367024 -3.5.4.9 * [butyribacterium] methylotrophicum 1.16 0.55 3 PMID:3316188 -3.5.4.9 * allium sp. 1.04 1.04 1 * -3.5.4.9 * asparagus officinalis 4.5 4.5 1 * -3.5.4.9 * bos taurus 0.65 0.39 2 PMID:13672973 -3.5.4.9 * brassica sp. 1.9 1.9 1 * -3.5.4.9 * cavia porcellus 1.04 0.35 3 PMID:13672973 -3.5.4.9 * clostridium formicaceticum 470.0 469.5 2 PMID:3702702;PMID:7061514 -3.5.4.9 * escherichia coli 31.0 31.0 1 PMID:1748668 -3.5.4.9 * felis sp. 0.41 0.27 3 PMID:13672973 -3.5.4.9 * flammulina velutipes 1.35 1.35 1 * -3.5.4.9 * gallus gallus 30.6 30.6 1 PMID:7417406 -3.5.4.9 * homo sapiens 161.0 22.4 7 PMID:10828945;PMID:11004530;PMID:11904299;PMID:13672973;PMID:9454603 -3.5.4.9 * lactuca sativa 1.3 1.3 1 * -3.5.4.9 * lathyrus oleraceus 32.9 0.525 8 * -3.5.4.9 * leishmania major 6.3 6.3 1 PMID:19183277 -3.5.4.9 * lentinula edodes 1.04 1.04 1 * -3.5.4.9 * methanosarcina barkeri 66.0 34.0 2 PMID:15349715 -3.5.4.9 * methylorubrum extorquens 104.0 104.0 1 PMID:10215859 -3.5.4.9 * mus musculus 0.5 0.4 3 PMID:13672973 -3.5.4.9 * neomoorella thermoacetica 0.94 0.63 3 PMID:6806250 -3.5.4.9 * oryctolagus cuniculus 0.82 0.25 3 PMID:13672973 -3.5.4.9 * ovis aries 0.434 0.14 3 PMID:13672973;PMID:6990198 -3.5.4.9 * petroselinum sp. 2.1 2.1 1 * -3.5.4.9 * photobacterium phosphoreum 97.4 97.4 1 PMID:8765228 -3.5.4.9 * pseudomonas fluorescens 0.29 0.29 1 PMID:13672973 -3.5.4.9 * rattus norvegicus 0.36 0.20500000000000002 4 PMID:12793858;PMID:13672973 -3.5.4.9 * saccharomyces cerevisiae 0.083 0.083 1 PMID:6990198 -3.5.4.9 * spinacia oleracea 3.7 2.7 3 * -3.5.4.9 * sus scrofa 2.2 1.2100000000000002 2 PMID:13672973 -3.5.4.9 * trifolium sp. 0.5 0.5 1 * -3.5.4.9 * vigna mungo 0.87 0.87 1 * -3.5.5.1 * acidovorax facilis 44.0 44.0 1 PMID:22441427 -3.5.5.1 * alcaligenes faecalis 0.62 0.4 3 PMID:22020513 -3.5.5.1 * alcaligenes sp. 25.6 22.3 2 PMID:20960011 -3.5.5.1 * arabidopsis thaliana 0.75 0.75 1 PMID:1555601 -3.5.5.1 * arthrobacter sp. 1.31 0.7150000000000001 2 PMID:16346987 -3.5.5.1 * aspergillus niger 91.6 48.25 2 PMID:17061133 -3.5.5.1 * cereibacter sphaeroides 0.075 0.075 1 PMID:21938420 -3.5.5.1 * comamonas testosteroni 68.0 68.0 1 PMID:7642130 -3.5.5.1 * fusarium proliferatum 14.6 14.6 1 PMID:25595333 -3.5.5.1 * fusarium solani 1.66 1.66 1 PMID:23761 -3.5.5.1 * fusarium verticillioides 0.64 0.46 2 PMID:21892598 -3.5.5.1 * nocardia sp. 15.7 15.7 1 PMID:21655 -3.5.5.1 * pseudomonas fluorescens 1.9 1.9 1 PMID:22020513 -3.5.5.1 * pseudomonas putida 1.26 1.26 1 PMID:18704770 -3.5.5.1 * pseudomonas sp. 17530.0 24.7 3 * -3.5.5.1 * pyrococcus sp. m24d13 3286.7 3286.7 1 PMID:26973832 -3.5.5.1 * pyrococcus sp. mc-fb 0.0037 0.0037 1 PMID:28744780 -3.5.5.1 * rhodococcus rhodochrous 15.3 8.62 8 PMID:1400390;PMID:18412544;PMID:19903476;PMID:9918784 -3.5.5.1 * rhodococcus sp. (in: high g+c gram-positive bacteria) 84.0 49.05 2 PMID:1388821;PMID:22020513 -3.5.5.1 * saccharolobus solfataricus 0.0006 0.0006 1 PMID:16156792 -3.5.5.1 * synechocystis sp. 0.1 0.1 1 PMID:22020513 -3.5.5.1 * talaromyces marneffei 0.7 0.47 2 PMID:21892598 -3.5.5.2 * pseudomonas sp. 12.0 12.0 1 * -3.5.5.4 * lupinus angustifolius 143.7 71.89999999999999 4 PMID:16786295 -3.5.5.4 * pseudomonas sp. 65.0 65.0 1 * -3.5.5.5 * alcaligenes faecalis 144.0 144.0 1 PMID:2269298 -3.5.5.5 * pseudomonas fluorescens 90.0 4.25 3 PMID:17693456 -3.5.5.5 * pseudomonas putida 22.8 16.03 11 PMID:16341723;PMID:18704770 -3.5.5.6 * klebsiella pneumoniae subsp. ozaenae 25.7 25.7 1 PMID:2834373 -3.5.5.7 * comamonas testosteroni 68.0 68.0 1 PMID:7642130 -3.5.5.7 * meyerozyma guilliermondii 15.8 7.2 21 PMID:10913974 -3.5.5.7 * pseudomonas fluorescens 1.9 1.7999999999999998 2 PMID:19153727 -3.5.5.7 * pseudomonas sp. 17.53 17.53 1 * -3.5.5.7 * pyrococcus abyssi 141.9 0.1419 3 PMID:16495079 -3.5.5.7 * rhodococcus rhodochrous 31.4 4.3 5 PMID:18412544;PMID:2394676 -3.5.5.7 * synechocystis sp. 3.2 0.97 5 PMID:25450592 -3.5.5.8 * thiobacillus thioparus 32.0 27.65 2 PMID:1577754;PMID:16879822 -3.5.5.8 * thiohalophilus thiocyanatoxydans 3.3 1.6649999999999998 2 PMID:17964868 -3.5.99.11 * comamonas testosteroni 0.196 0.17149999999999999 2 PMID:17259310 -3.5.99.11 * ectopseudomonas oleovorans 37.8 37.8 1 PMID:9573204 -3.5.99.12 * homo sapiens 9.959e-05 4.9824e-05 2 PMID:8843103 -3.5.99.13 * catharanthus roseus 31.62 1.625 4 PMID:476085;PMID:510306;PMID:7887913 -3.5.99.13 * rauvolfia serpentina 11.04 7.38 2 PMID:7764480 -3.5.99.14 * thalictrum flavum ssp. glaucum 0.09 0.09 1 PMID:12107162 -3.5.99.16 * alangium lamarckii 43.02 21.549000000000003 2 PMID:11065292 -3.5.99.2 * bacillus subtilis 0.292 0.1835 4 PMID:25014715 -3.5.99.2 * staphylococcus aureus 0.0046 0.0046 1 PMID:19888457 -3.5.99.5 * ectopseudomonas oleovorans 37.8 37.8 1 PMID:9573204 -3.5.99.6 * aspergillus niger 0.036 0.036 1 PMID:18214472 -3.5.99.6 * canis lupus familiaris 85.0 85.0 1 PMID:1497340 -3.5.99.6 * escherichia coli 606.8 158.0 3 PMID:13549465;PMID:236479;PMID:6375729 -3.5.99.6 * giardia duodenalis 308.0 62.0 5 PMID:25326378;PMID:9041531 -3.5.99.6 * sus scrofa 52.0 52.0 1 PMID:13549465 -3.5.99.7 * cyberlindnera saturnus 1.38 1.38 1 * -3.5.99.7 * methylobacterium nodulans 0.74 0.74 1 PMID:23517598 -3.5.99.7 * methylobacterium oryzae 0.005 0.005 1 * -3.5.99.7 * methylobacterium radiotolerans 0.44 0.22285 2 PMID:23517598 -3.5.99.7 * methylobacterium sp. 0.0074 0.0074 1 * -3.5.99.7 * pseudomonas brassicacearum 0.00017 0.00017 1 PMID:17322547 -3.5.99.7 * pseudomonas chlororaphis 0.36 0.36 1 * -3.5.99.7 * pseudomonas fluorescens 0.0054 0.0054 1 * -3.5.99.7 * pseudomonas putida 2.812 0.0483 7 PMID:18560939;PMID:18825405 -3.5.99.7 * pseudomonas sp. 3.49 3.49 1 * -3.5.99.9 * mycobacterium sp. 0.0236 0.0173 2 PMID:21244596 -3.6.1.1 * acidithiobacillus thiooxidans 804.1 804.1 1 PMID:14950 -3.6.1.1 * amaranthus blitum 80.0 80.0 1 * -3.6.1.1 * aquifex aeolicus 1.13 1.13 1 PMID:11676598 -3.6.1.1 * arabidopsis thaliana 0.00705 0.00705 1 PMID:21122813 -3.6.1.1 * aranda christine 2.7 2.7 1 * -3.6.1.1 * ascaris suum 940.0 473.875 2 PMID:15784540 -3.6.1.1 * aspergillus oryzae 13.1 13.1 1 PMID:4358816 -3.6.1.1 * bacillus subtilis 5375.0 5375.0 1 PMID:9633597 -3.6.1.1 * bos taurus 2.1 2.1 1 PMID:9143364 -3.6.1.1 * caenorhabditis elegans 1570.0 1570.0 1 PMID:17981157 -3.6.1.1 * desulfovibrio desulfuricans 320.0 320.0 1 PMID:5132274 -3.6.1.1 * dunaliella salina 56.5 56.5 1 * -3.6.1.1 * enterococcus faecalis 14.4 14.4 1 PMID:6116703 -3.6.1.1 * escherichia coli 360.0 82.0 7 PMID:15701051;PMID:17309439;PMID:22984449 -3.6.1.1 * geobacillus stearothermophilus 1800.0 1800.0 1 PMID:5398 -3.6.1.1 * gossypium hirsutum 415.0 327.5 2 * -3.6.1.1 * helicobacter pylori 141.7 141.7 1 PMID:10985749 -3.6.1.1 * homo sapiens 79.75 79.75 1 PMID:656444 -3.6.1.1 * hypophthalmichthys nobilis 2.52 2.52 1 * -3.6.1.1 * leishmania major 154.3 154.3 1 PMID:14988016 -3.6.1.1 * methanocaldococcus jannaschii 8000.0 4300.0 2 PMID:10898947 -3.6.1.1 * methanothermobacter thermautotrophicus 1233.0 1233.0 1 PMID:8003527 -3.6.1.1 * methanothrix thermoacetophila 726.0 441.5 2 PMID:22927778 -3.6.1.1 * oryctolagus cuniculus 680.0 680.0 1 PMID:25268 -3.6.1.1 * papaver rhoeas 2320.0 2245.0 2 PMID:17086195 -3.6.1.1 * pyrococcus furiosus 0.0559 0.0559 1 * -3.6.1.1 * pyrococcus horikoshii 101.6 101.6 1 PMID:24755063 -3.6.1.1 * rattus norvegicus 600.0 300.25 2 PMID:17415680;PMID:6125258 -3.6.1.1 * saccharum officinarum 6.0 4.35 2 * -3.6.1.1 * sorghum bicolor 478.0 478.0 1 PMID:2829731 -3.6.1.1 * spinacia oleracea 6.7 6.7 1 PMID:9328290 -3.6.1.1 * streptococcus salivarius 33.6 33.6 1 PMID:6125251 -3.6.1.1 * sulfolobus acidocaldarius 860.0 633.5 6 PMID:10049508;PMID:1315573;PMID:1321720;PMID:7771779;PMID:8282721 -3.6.1.1 * sus scrofa 1986.0 1986.0 1 PMID:6132917 -3.6.1.1 * thermoplasma acidophilum 1200.0 1200.0 1 PMID:1327774 -3.6.1.1 * zea mays 592.0 592.0 1 * -3.6.1.10 * saccharomyces cerevisiae 65000.0 135.0 10 PMID:15792812;PMID:31175919 -3.6.1.11 * chlorobaculum tepidum 590.0 170.0 5 PMID:24969471 -3.6.1.11 * corynebacterium glutamicum 0.8 0.275 4 PMID:19304823 -3.6.1.11 * escherichia coli 22.4 12.1 7 PMID:15489502 -3.6.1.11 * rhipicephalus microplus 1.26 1.26 1 PMID:17785198 -3.6.1.11 * saccharomyces cerevisiae 2070.0 0.1095 36 PMID:15061692;PMID:15170373;PMID:15925310;PMID:17599355;PMID:18976214;PMID:25742176;PMID:31175919;PMID:9650588 -3.6.1.13 * artemia sp. 1.2 1.2 1 PMID:8645701 -3.6.1.13 * homo sapiens 8.59 8.59 1 PMID:9693963 -3.6.1.13 * rattus norvegicus 18.2 12.81 3 PMID:7819284 -3.6.1.14 * lupinus luteus 20.83 20.83 1 PMID:9359862 -3.6.1.15 * pseudomonas aeruginosa 0.00018 0.00012 3 PMID:18174131 -3.6.1.15 * rattus norvegicus 25.4 13.649999999999999 2 PMID:27293;PMID:2867090 -3.6.1.15 * west nile virus 160.8 160.8 1 PMID:11238848 -3.6.1.17 * arabidopsis thaliana 70.5 29.05 6 PMID:18345354 -3.6.1.17 * artemia salina 0.2 0.01225 4 PMID:4368591;PMID:4955726 -3.6.1.17 * homo sapiens 52.0 9.25011 4 PMID:1652465;PMID:8381042 -3.6.1.17 * mus musculus 0.276 0.14170000000000002 2 PMID:6286385 -3.6.1.17 * photinus pyralis 13.5 6.76 2 PMID:7876110 -3.6.1.17 * rattus norvegicus 0.436 0.219 2 PMID:163189 -3.6.1.18 * lathyrus oleraceus 0.000482 0.0001907 4 PMID:18713732 -3.6.1.18 * rattus norvegicus 250000.0 40.229 6 PMID:2987256;PMID:5636362;PMID:6120218;PMID:7691801;PMID:9395326 -3.6.1.21 * escherichia coli 9.511 6.6 3 PMID:11416161;PMID:5330035 -3.6.1.22 * nicotiana tabacum 0.17 0.17 1 PMID:24241855 -3.6.1.22 * proteus vulgaris 0.78 0.3904 2 PMID:4405504 -3.6.1.22 * salmonella enterica subsp. enterica serovar typhimurium 0.29 0.29 1 * -3.6.1.23 * homo sapiens 16.0 1.46 3 PMID:6130763;PMID:6143756;PMID:6147344 -3.6.1.23 * human alphaherpesvirus 1 2.171 2.171 1 PMID:6147344 -3.6.1.23 * leishmania major 44.06 44.06 1 PMID:10657253 -3.6.1.23 * methanocaldococcus jannaschii 8.8 8.8 1 PMID:19683509 -3.6.1.23 * mus musculus 0.0105 0.0105 1 PMID:5105331 -3.6.1.23 * paramecium bursaria chlorella virus 1 23.9 23.9 1 PMID:16014955 -3.6.1.23 * plasmodium falciparum 25.75 25.75 1 PMID:15698576 -3.6.1.23 * spbetavirus spbeta 69.0 69.0 1 PMID:15939294 -3.6.1.24 * escherichia coli 6670.0 3335.0009 2 PMID:4318904 -3.6.1.25 * brachypodium distachyon 0.0115 0.007 3 PMID:31785160 -3.6.1.25 * rattus norvegicus 0.588 0.372 2 PMID:11278456 -3.6.1.27 * bacillus subtilis 0.73 0.23 3 PMID:15946938 -3.6.1.27 * escherichia coli 310.0 8.5 8 PMID:18411271;PMID:26560897 -3.6.1.27 * helicobacter pylori 6039.0 15.061499999999999 6 PMID:31487328 -3.6.1.28 * bos taurus 648.0 0.309 11 PMID:11827967;PMID:12943234;PMID:1329971 -3.6.1.28 * gallus gallus 0.932 0.4717 2 PMID:12943234 -3.6.1.28 * homo sapiens 225.0 103.0 5 PMID:11827967;PMID:12943234;PMID:15109578;PMID:16000236 -3.6.1.28 * quail 0.0024 0.0006 5 PMID:12943234 -3.6.1.28 * rattus norvegicus 1.69 0.299 5 PMID:12943234;PMID:4335862 -3.6.1.28 * sus scrofa 0.048 0.0286 4 PMID:12943234;PMID:16000236 -3.6.1.29 * artemia sp. 0.0075 0.0075 1 PMID:1325380 -3.6.1.29 * escherichia coli 127.0 127.0 1 PMID:3031018 -3.6.1.29 * homo sapiens 1.34 0.68 2 PMID:10733886;PMID:16359767 -3.6.1.29 * lupinus luteus 0.07 0.07 1 PMID:6309793 -3.6.1.29 * rattus norvegicus 300.0 4.8 9 PMID:1849011;PMID:196848;PMID:2995162;PMID:6088316 -3.6.1.29 * saccharomyces cerevisiae 0.75 0.75 1 PMID:1653209 -3.6.1.31 * saccharomyces cerevisiae 332.0 332.0 1 PMID:379004 -3.6.1.31 * salmonella enterica subsp. enterica serovar typhimurium 0.003 0.003 1 PMID:14342333 -3.6.1.40 * escherichia coli 7000.0 767.5 4 PMID:6130093;PMID:8394006 -3.6.1.41 * escherichia coli 0.062 0.062 1 PMID:6317672 -3.6.1.42 * arabidopsis thaliana 21.7 11.014999999999999 2 PMID:25822168 -3.6.1.42 * bos taurus 4000.0 4000.0 1 PMID:2989286 -3.6.1.42 * saccharomyces cerevisiae 3080.0 3080.0 1 PMID:2172253 -3.6.1.43 * bos taurus 0.0031 0.0031 1 PMID:6094565 -3.6.1.43 * mus musculus 0.016 0.0105 2 PMID:12198133 -3.6.1.43 * rattus norvegicus 0.032 0.0175 2 PMID:1846175 -3.6.1.45 * corynebacterium glutamicum 0.55 0.313 2 PMID:16085822 -3.6.1.45 * escherichia coli 12.58 12.58 1 PMID:5337593 -3.6.1.45 * salmonella enterica subsp. enterica serovar typhimurium 10.0 10.0 1 PMID:6297400 -3.6.1.5 * arabidopsis thaliana 21.7 21.7 1 PMID:25822168 -3.6.1.5 * bos taurus 639.0 0.285 10 PMID:1610912;PMID:18976223;PMID:2820077 -3.6.1.5 * bothrops jararaca 1.806 0.1235 4 PMID:17504098 -3.6.1.5 * cicer arietinum 1800.0 1800.0 1 PMID:6275835 -3.6.1.5 * gallus gallus 1242.0 1242.0 1 PMID:11985621 -3.6.1.5 * homo sapiens 1020.0 511.165 2 PMID:18295590 -3.6.1.5 * hordeum vulgare 2.1 1.0 7 PMID:8829808 -3.6.1.5 * lathyrus oleraceus 0.94 0.54 6 PMID:8829808 -3.6.1.5 * lupinus luteus 98.0 1.4 6 PMID:1668272;PMID:8829808 -3.6.1.5 * mimosa pudica 1140.0 576.4 4 PMID:21788364 -3.6.1.5 * mus musculus 0.1364 0.1286 2 PMID:28871607 -3.6.1.5 * ornithodoros savignyi 360.0 280.0 3 PMID:14598857 -3.6.1.5 * rattus norvegicus 2.275 0.562 8 PMID:16480902;PMID:7773186;PMID:8177226;PMID:8673003;PMID:9144325 -3.6.1.5 * rhodnius prolixus 580.0 335.0 3 PMID:3010945 -3.6.1.5 * secale cereale 2.5 0.3 6 PMID:8829808 -3.6.1.5 * solanum tuberosum 4.2 0.6499999999999999 10 PMID:8829808 -3.6.1.5 * sus scrofa 94.7 15.2 13 PMID:10681547;PMID:12899702;PMID:6243296;PMID:6277950 -3.6.1.5 * triatoma infestans 1500.0 1350.0 2 PMID:14985353 -3.6.1.5 * triticosecale wittmack 3.6 0.56 6 PMID:8829808 -3.6.1.5 * triticum aestivum 12.7 1.4 6 PMID:8829808 -3.6.1.5 * trypanosoma cruzi 0.4 0.319 2 PMID:19255624 -3.6.1.5 * zea mays 1.4 0.1 5 PMID:8829808 -3.6.1.53 * rattus norvegicus 18.2 18.2 1 PMID:7819284 -3.6.1.54 * caulobacter vibrioides 30.0 27.5 2 PMID:20608695 -3.6.1.54 * escherichia coli 63.2 63.2 1 PMID:12000770 -3.6.1.54 * haemophilus influenzae 7.8 7.8 1 PMID:23897835 -3.6.1.55 * ciona intestinalis 11.8 11.8 1 PMID:21178309 -3.6.1.55 * hordeum vulgare subsp. vulgare 18300.0 18300.0 1 PMID:25379607 -3.6.1.6 * acer pseudoplatanus 2.8 2.5 2 * -3.6.1.6 * rattus norvegicus 358.1 192.64999999999998 4 PMID:210795;PMID:210813;PMID:2828050 -3.6.1.65 * escherichia coli 193.0 193.0 1 PMID:11053429 -3.6.1.67 * arabidopsis thaliana 0.0017 0.0017 1 PMID:15611104 -3.6.1.67 * escherichia coli 3.0 3.0 1 PMID:17698004 -3.6.1.67 * lactococcus lactis 0.65 0.65 1 PMID:15611104 -3.6.1.67 * limosilactobacillus reuteri 28.2 28.2 1 PMID:38888337 -3.6.1.7 * bos taurus 7000.0 3675.0 6 PMID:14435883;PMID:237200;PMID:8262761;PMID:8276101 -3.6.1.7 * cavia porcellus 3600.0 3500.0 3 PMID:6320809 -3.6.1.7 * equus caballus 3900.0 3500.0 9 PMID:237200;PMID:4305161;PMID:4344156;PMID:6314903;PMID:6320809 -3.6.1.7 * gallus gallus 8500.0 6000.0 5 PMID:2830253;PMID:3001041 -3.6.1.7 * homo sapiens 7500.0 3975.0 16 PMID:237200;PMID:3026468;PMID:7720867;PMID:8385494;PMID:8746632;PMID:8838587 -3.6.1.7 * meleagris gallopavo 9000.0 3500.0 3 PMID:1964788;PMID:6320809 -3.6.1.7 * oryctolagus cuniculus 7500.0 3600.0 3 PMID:4313603 -3.6.1.7 * rattus norvegicus 3281.0 3281.0 1 PMID:1647162 -3.6.1.7 * sus scrofa 10800.0 7200.0 5 PMID:237200;PMID:2834344;PMID:6094516 -3.6.1.75 * saccharomyces cerevisiae 150.0 0.29 3 PMID:10545184;PMID:8567632 -3.6.1.8 * rattus norvegicus 0.03 0.03 1 PMID:149537 -3.6.1.9 * bothrops jararaca 242.0 0.9850000000000001 6 PMID:19481561 -3.6.1.9 * glaesserella parasuis 13.5 13.5 1 PMID:9453136 -3.6.1.9 * haemophilus influenzae 3500.0 3500.0 1 PMID:3009442 -3.6.1.9 * homo sapiens 75.0 75.0 1 PMID:3001038 -3.6.1.9 * hordeum vulgare 354.1 290.35 2 PMID:11172808 -3.6.1.9 * lens culinaris 16.9 16.9 1 PMID:10981813 -3.6.1.9 * opuntia ficus-indica 420.0 420.0 1 * -3.6.1.9 * ovis aries aries 107.0 107.0 1 PMID:4677240 -3.6.1.9 * rattus norvegicus 2894.0 2894.0 1 PMID:16421009 -3.6.1.9 * rattus sp. 411.0 79.0 6 PMID:1149736;PMID:11946484;PMID:2987256;PMID:4403504;PMID:7532398;PMID:9462844 -3.6.1.9 * saccharomyces sp. 640.0 640.0 1 PMID:4401058 -3.6.1.9 * solanum tuberosum 2831.0 50.3 3 PMID:6147251;PMID:8110 -3.6.1.9 * triticum aestivum 188.2 188.2 1 * -3.6.2.1 * bos taurus 42.2 24.1 2 PMID:214136;PMID:4348176 -3.6.2.1 * comamonas terrigena 0.014 0.014 1 * -3.6.4.6 * rattus norvegicus 0.3 0.3 1 PMID:9824302 -3.6.4.6 * saccharomyces cerevisiae 1.56 1.0050000000000001 2 PMID:9155008;PMID:9824302 -3.6.4.6 * xenopus laevis 0.72 0.40149999999999997 2 PMID:7646486;PMID:9824302 -3.6.5.1 * bos taurus 0.722 0.722 1 PMID:7890762 -3.6.5.2 * homo sapiens 0.001 0.001 1 PMID:1784275 -3.6.5.2 * pseudomonas aeruginosa 2.83e-05 2.83e-05 1 PMID:9079902 -3.6.5.4 * pyrococcus abyssi 0.012 0.012 1 PMID:17468740 -3.6.5.5 * rattus norvegicus 0.16 0.16 1 PMID:16622417 -3.6.5.6 * bos taurus 2.0 2.0 1 PMID:8193140 -3.6.5.6 * capra hircus 7.1 6.35 2 PMID:17069615 -3.7.1.1 * aspergillus niger 58.0 57.0 2 PMID:10778746 -3.7.1.1 * botrytis cinerea 20.0 9.8 4 PMID:17244616 -3.7.1.1 * cryphonectria parasitica 0.2 0.2 1 PMID:3688887 -3.7.1.1 * fomitopsis palustris 0.3 0.3 1 PMID:11553780 -3.7.1.1 * streptantibioticus cattleyicolor 0.2 0.2 1 PMID:3688887 -3.7.1.11 * azoarcus sp. 0.677 0.677 1 PMID:21965568 -3.7.1.13 * metapseudomonas resinovorans 3.84 3.84 1 PMID:12619671 -3.7.1.13 * pseudomonas sp. 2600.0 2600.0 1 PMID:12651123 -3.7.1.18 * rhodococcus sp. (in: high g+c gram-positive bacteria) 357.5 357.5 1 PMID:11278926 -3.7.1.2 * bos taurus 36.3 18.325 2 PMID:13916;PMID:5027618 -3.7.1.2 * felis catus 0.055 0.0405 2 PMID:18880754 -3.7.1.2 * homo sapiens 1558.0 779.0002 2 PMID:2195095;PMID:8473520 -3.7.1.2 * mus musculus 0.0803 0.0689 2 PMID:18880754 -3.7.1.2 * oryctolagus cuniculus 0.027 0.0225 2 PMID:18880754 -3.7.1.2 * rattus norvegicus 69.3 0.111 23 PMID:18880754;PMID:728842 -3.7.1.2 * rhodotorula diobovata 1.77 1.77 1 PMID:25832819 -3.7.1.21 * geobacter metallireducens 2.0 2.0 1 PMID:18312395 -3.7.1.21 * syntrophus aciditrophicus 0.5 0.5 1 PMID:18312395 -3.7.1.21 * thauera aromatica 1.3 1.3 1 PMID:10406950 -3.7.1.22 * bacillus subtilis 253.0 253.0 1 PMID:18310071 -3.7.1.23 * aquipseudomonas alcaligenes 8.8 4.485 2 PMID:7400101 -3.7.1.24 * pseudomonas sp. 9.1 9.1 1 PMID:22790955 -3.7.1.25 * pseudomonas putida 48.0 24.29 2 * -3.7.1.25 * pseudomonas sp. js42 0.272 0.272 1 PMID:7944378 -3.7.1.3 * cavia porcellus 9e-05 9e-05 1 PMID:15206763 -3.7.1.3 * homo sapiens 1.75 0.164 5 PMID:11354681;PMID:11985583;PMID:14505498;PMID:17300176;PMID:1772066 -3.7.1.3 * mus musculus 4e-05 2.5e-05 2 PMID:15206763 -3.7.1.3 * neurospora crassa 12.56 10.0 3 PMID:13129249;PMID:136367;PMID:158014;PMID:6432787 -3.7.1.3 * oryctolagus cuniculus 3e-05 2e-05 7 PMID:15206763;PMID:15530458 -3.7.1.3 * priestia megaterium 31.25 9.55 4 PMID:803956 -3.7.1.3 * pseudomonas fluorescens 16.6 8.9 2 PMID:11354681;PMID:9264543 -3.7.1.3 * pseudomonas marginalis 10.0 10.0 1 PMID:13129249;PMID:6432787 -3.7.1.3 * rattus norvegicus 0.25 0.0114 6 PMID:13032082;PMID:15206763;PMID:162555;PMID:1772066;PMID:4008484;PMID:7451426 -3.7.1.3 * suncus murinus 0.026 0.026 1 PMID:1772066 -3.7.1.3 * sus scrofa 68.3 34.4805 2 PMID:457635 -3.7.1.4 * aspergillus niger 3.6 3.6 1 PMID:5441377 -3.7.1.4 * eubacterium ramulus 8.7 8.7 3 PMID:15466559 -3.7.1.4 * pantoea agglomerans 213.0 213.0 1 PMID:5354935 -3.7.1.4 * platyrrhini 0.45 0.45 1 PMID:810166 -3.7.1.5 * homo sapiens 0.014 0.014 1 PMID:21878618 -3.7.1.6 * pseudomonas putida 4.8 2.8 2 PMID:10438778;PMID:236305 -3.7.1.7 * pseudomonas sp. 1.65 0.99 2 PMID:10746768 -3.7.1.7 * sphingomonas sp. 2.6 1.35 2 PMID:15817792 -3.7.1.7 * sphingopyxis sp. 598.0 598.0 1 PMID:24068496 -3.7.1.8 * bacillus sp. (in: firmicutes) 1.34 1.34 1 PMID:16339959 -3.7.1.8 * pseudomonas sp. 2600.0 6.4 3 PMID:12430413;PMID:12651123;PMID:15480459 -3.7.1.8 * pseudomonas sp. 'cruciviae' 51.39 51.39 1 * -3.7.1.8 * rhodococcus globerulus 13.2 13.2 1 PMID:11160080 -3.7.1.9 * arthrobacter sp. 28.1 28.1 1 PMID:10746195 -3.7.1.9 * cupriavidus necator 17.4 13.75 2 * -3.7.1.9 * pseudomonas putida 48.0 48.0 1 * -3.7.1.9 * pseudomonas sp. 28.4 3.87 3 PMID:23009925 -3.8.1.10 * pseudomonas sp. 30.0 30.0 1 PMID:8074519 -3.8.1.2 * agrobacterium tumefaciens 0.23 0.23 1 PMID:9425247 -3.8.1.2 * azotobacter sp. 0.7 0.7 1 * -3.8.1.2 * burkholderia cepacia 4.56 4.56 1 PMID:10498712 -3.8.1.2 * hymeniacidon perlevis 0.06 0.06 1 PMID:21298680 -3.8.1.2 * pseudomonas putida 120.0 120.0 1 PMID:8074519 -3.8.1.2 * pseudomonas sp. 120.0 109.0 4 PMID:1772590;PMID:7490277;PMID:7579997;PMID:8074519 -3.8.1.2 * stutzerimonas chloritidismutans 2.1 1.49 8 PMID:28411224 -3.8.1.2 * sulfurisphaera tokodaii 20.0 4.65 4 PMID:19714319 -3.8.1.3 * moraxella sp. 0.01 0.01 1 PMID:7765567 -3.8.1.3 * pseudomonas sp. 120.0 79.2 2 PMID:5817816 -3.8.1.5 * alloalcanivorax dieselolei 26.48 3.585 36 PMID:24586552 -3.8.1.5 * ancylobacter aquaticus 92.3 92.3 1 PMID:24642226 -3.8.1.5 * bacillus sp. (in: firmicutes) 317.0 134.0 14 PMID:14720543 -3.8.1.5 * burkholderia sp. 352.0 158.5 14 PMID:14720543 -3.8.1.5 * corynebacterium sp. 282.0 129.0 14 PMID:14720543 -3.8.1.5 * micrococcus sp. 329.0 141.0 14 PMID:14720543 -3.8.1.5 * mycobacterium avium 0.6 0.30033 2 PMID:17084094 -3.8.1.5 * pseudomonas sp. 346.0 148.0 14 PMID:14720543 -3.8.1.5 * rhodococcus erythropolis 2.4 2.4 1 PMID:15929125 -3.8.1.5 * sphingobium indicum 0.004 0.00236 2 PMID:17451982;PMID:22385211 -3.8.1.5 * sphingomonas paucimobilis 15.6 1.87 14 PMID:11939779;PMID:14525993;PMID:16216524 -3.8.1.5 * uncultured bacterium 12.2 8.53 2 PMID:28674849 -3.8.1.5 * xanthobacter autotrophicus 0.08 0.08 1 PMID:15929125 -3.8.1.6 * arthrobacter sp. 1.5 1.5 1 * -3.8.1.7 * arthrobacter sp. 3.61 0.349 17 PMID:15068371;PMID:17431803 -3.8.1.7 * pseudomonas sp. 2.25 1.875 2 PMID:11695894;PMID:7579994 -3.8.1.8 * agrobacterium tumefaciens 0.0048 0.0048 1 PMID:11010866 -3.8.1.8 * alcaligenes sp. 0.0039 0.0039 1 PMID:11010866 -3.8.1.8 * arthrobacter sp. 1.105 1.105 1 * -3.8.1.8 * clavibacter michiganese 0.0001 0.0001 1 PMID:11010866 -3.8.1.8 * haematococcus lacustris 15.6 8.1 18 PMID:27010688 -3.8.1.8 * pseudomonas sp. 4.5 1.05 7 PMID:11010866;PMID:12450410;PMID:17660279;PMID:24237144;PMID:8759853 -3.8.1.8 * ralstonia pickettii 0.0017 0.0017 1 PMID:11010866 -3.8.1.8 * rhizobium sp. 0.0162 0.01035 2 PMID:11010866;PMID:16535552 -3.8.1.9 * hymeniacidon perlevis 0.12 0.12 1 * -3.8.2.2 * alteromonas sp. 300.0 148.6 4 PMID:2001997;PMID:8633861 -3.8.2.2 * doryteuthis pealeii 18.64 18.64 1 PMID:4339736 -3.8.2.2 * homo sapiens 17.95 15.875 2 PMID:27838376 -3.8.2.2 * loligo vulgaris 382.39 198.0 7 PMID:11162408;PMID:15966726;PMID:22401958;PMID:26239441 -3.8.2.2 * pseudoalteromonas haloplanktis 65.3 34.0 2 * -3.8.2.2 * pseudoalteromonas undina 575.0 451.4 2 PMID:16349054 -3.8.2.2 * rattus norvegicus 1.512 0.998 5 PMID:15251439 -3.8.2.2 * todarodes pacificus 18.3 18.3 1 PMID:8263902 -3.9.1.1 * bos taurus 4.8 3.5 2 PMID:13491564 -3.9.1.1 * rattus norvegicus 0.181 0.17049999999999998 2 PMID:4308726 -3.9.1.3 * homo sapiens 1.8 1.1 2 PMID:16219293 -3.9.1.3 * sus scrofa 2.72 1.3614000000000002 2 PMID:12383260 -4.1.1.1 * acetobacter pasteurianus 89.3 0.7 18 PMID:24099461 -4.1.1.1 * gluconacetobacter diazotrophicus 43.0 12.0 5 PMID:25369873 -4.1.1.1 * gluconobacter oxydans 125.0 52.0 4 PMID:24276622 -4.1.1.1 * ipomoea batatas 12.3 8.005 2 PMID:5400 -4.1.1.1 * lachancea kluyveri 1.81 0.7949999999999999 4 PMID:14648197 -4.1.1.1 * lactococcus lactis 80.7 80.7 1 PMID:15358422 -4.1.1.1 * lactococcus lactis subsp. lactis 26.77 24.005 2 PMID:26350079 -4.1.1.1 * nakaseomyces glabratus 40.0 30.85 2 PMID:15625313 -4.1.1.1 * populus deltoides 14.34 7.22 2 PMID:19698964 -4.1.1.1 * pseudothermotoga hypogea 1.9 1.9 1 PMID:26032540 -4.1.1.1 * rhizopus arrhizus 75.4 67.4 2 * -4.1.1.1 * saccharomyces cerevisiae 45.0 16.9 11 PMID:10651824;PMID:11327837;PMID:11412091 -4.1.1.1 * thermococcus guaymasensis 3.8 3.8 1 PMID:24982594 -4.1.1.1 * thermococcus kodakarensis 3.8 3.8 1 * -4.1.1.1 * thermotoga maritima 1.4 1.4 1 PMID:26032540 -4.1.1.1 * thermus thermophilus 1.45 1.45 1 PMID:26731734 -4.1.1.1 * tritrichomonas suis 5.7 5.7 1 PMID:15155220 -4.1.1.1 * zea mays 96.4 69.0 2 PMID:16664379 -4.1.1.1 * zymobacter palmae 147.0 2.3 16 PMID:32625027 -4.1.1.1 * zymomonas mobilis 181.0 150.5 2 PMID:11327837 -4.1.1.101 * lactiplantibacillus plantarum 265.0 265.0 1 PMID:6833282 -4.1.1.101 * leuconostoc mesenteroides 16.23 16.23 1 PMID:16345941 -4.1.1.101 * oenococcus oeni 419.2 419.2 1 * -4.1.1.102 * enterobacter sp. 16.3 16.3 1 PMID:26059194 -4.1.1.102 * meyerozyma guilliermondii 378.0 378.0 1 PMID:22217315 -4.1.1.103 * agrobacterium tumefaciens 1.57 1.57 1 PMID:15474471 -4.1.1.11 * [pseudomonas] dacunhae 65.95 65.95 1 * -4.1.1.11 * bacillus subtilis 15.7 8.4 3 PMID:26762040 -4.1.1.11 * corynebacterium glutamicum 690.0 4.96 6 PMID:24104602;PMID:24737081;PMID:26762040 -4.1.1.11 * escherichia coli 0.98 0.815 2 PMID:26762040;PMID:3003510;PMID:381298 -4.1.1.11 * lactiplantibacillus plantarum 5.5 3.5 2 * -4.1.1.11 * methanocaldococcus jannaschii 0.09 0.09 1 PMID:24891443 -4.1.1.11 * mycobacterium tuberculosis 2.1 2.1 1 PMID:12182836 -4.1.1.11 * priestia aryabhattai 3.0 3.0 1 PMID:36708489 -4.1.1.11 * tribolium castaneum 4.83 4.83 1 PMID:31696283 -4.1.1.112 * corynebacterium glutamicum 158.0 158.0 1 PMID:7771770 -4.1.1.112 * komagataeibacter xylinus 360.0 360.0 1 PMID:206534 -4.1.1.112 * micrococcus luteus 890.0 890.0 1 * -4.1.1.112 * saccharolobus solfataricus 2.3 2.3 1 PMID:3142524 -4.1.1.112 * stutzerimonas stutzeri 319.0 319.0 1 PMID:10222034 -4.1.1.112 * sus scrofa 0.54 0.3 3 PMID:35253790 -4.1.1.112 * veillonella parvula 18.9 18.9 1 PMID:7076619 -4.1.1.112 * zea mays 3.15 3.15 1 * -4.1.1.12 * [pseudomonas] dacunhae 230.0 230.0 1 * -4.1.1.12 * comamonas testosteroni 215.0 145.225 2 * -4.1.1.12 * mycobacterium tuberculosis 2.1 2.1 1 PMID:12182836 -4.1.1.12 * pseudomonas dacunhae 0.084 0.084 1 PMID:5773301 -4.1.1.12 * pseudomonas sp. 280.0 74.55000000000001 4 PMID:16847601;PMID:17353007;PMID:18602363 -4.1.1.15 * enterococcus faecium 78.2 78.2 1 * -4.1.1.15 * enterococcus raffinosus 21.7 21.7 1 PMID:28101806 -4.1.1.15 * escherichia coli 193.4 100.6 4 PMID:17253644;PMID:27438707;PMID:3910996 -4.1.1.15 * felis catus 3.25 3.25 1 PMID:8080275 -4.1.1.15 * homo sapiens 2.956 1.37 7 PMID:10673368;PMID:10862868;PMID:12067524;PMID:15893607 -4.1.1.15 * lacticaseibacillus paracasei 16.7 16.7 1 PMID:18256502 -4.1.1.15 * lactiplantibacillus plantarum 26.7 26.7 1 PMID:33990858 -4.1.1.15 * levilactobacillus brevis 94.2 59.385000000000005 2 PMID:32041144;PMID:34153863 -4.1.1.15 * levilactobacillus senmaizukei 139.6 139.6 1 PMID:32464198 -4.1.1.15 * macaca fuscata 0.0011 0.0011 1 PMID:18776697 -4.1.1.15 * neurospora crassa 2.76 2.76 1 PMID:1825829 -4.1.1.15 * oryza sativa 710.0 107.15 10 PMID:17562689;PMID:20355097;PMID:20355143 -4.1.1.15 * priestia megaterium 148.0 103.5 2 PMID:26956237 -4.1.1.15 * solanum tuberosum 148.4 148.4 1 PMID:2862040 -4.1.1.15 * streptococcus thermophilus 103.5 103.5 2 * -4.1.1.15 * sus scrofa 0.462 0.462 1 PMID:8125937 -4.1.1.15 * vicia faba 21.44 21.44 1 PMID:23411329 -4.1.1.15 * vigna unguiculata 2.57 2.57 1 * -4.1.1.17 * aspergillus terreus 2.1 2.1 1 PMID:31362455 -4.1.1.17 * badhamia polycephala 20.0 19.9 2 PMID:6621381;PMID:6706929 -4.1.1.17 * entamoeba histolytica 24.8 12.41095 2 PMID:12594962;PMID:18235846 -4.1.1.17 * escherichia coli 130.0 114.5 2 PMID:6353148 -4.1.1.17 * homo sapiens 6.0 3.055 2 PMID:12859253;PMID:17582600 -4.1.1.17 * hordeum vulgare 0.33 0.185 2 * -4.1.1.17 * mus musculus 17.0 1.36 3 PMID:3392002;PMID:3753469;PMID:6621384 -4.1.1.17 * neurospora crassa 43.5 43.5 1 PMID:2953728 -4.1.1.17 * oryctolagus cuniculus 3.11e-05 8.550000000000001e-06 4 PMID:16753448 -4.1.1.17 * pelophylax nigromaculatus 3.75 3.75 1 PMID:1959325 -4.1.1.17 * plasmodium falciparum 7.8 0.0388 3 PMID:11085920;PMID:11390378;PMID:3139441 -4.1.1.17 * pseudomonas savastanoi pv. phaseolicola 3.3 3.3 1 * -4.1.1.17 * rattus norvegicus 1.038 0.193 3 PMID:5073764;PMID:6621383;PMID:7341240 -4.1.1.17 * saccharomyces cerevisiae 0.52 0.52 1 PMID:6353149 -4.1.1.17 * shewanella xiamenensis 11.91 11.91 1 PMID:36605515 -4.1.1.17 * tetrahymena pyriformis 0.23 0.23 1 PMID:3931682 -4.1.1.17 * thermus thermophilus 0.078 0.078 1 PMID:10395069 -4.1.1.17 * trichomonas vaginalis 0.859 0.859 1 PMID:8343128 -4.1.1.18 * aliivibrio salmonicida 205.1 149.6 2 * -4.1.1.18 * bacterium cadaveris 85.7 85.7 1 PMID:5762458 -4.1.1.18 * escherichia coli 1018.0 510.95 4 PMID:27780956;PMID:4590109;PMID:6353151 -4.1.1.18 * glycine max 17.8 17.8 1 PMID:9633596 -4.1.1.18 * hafnia alvei 1825.0 1825.0 1 PMID:31337154 -4.1.1.18 * selenomonas ruminantium 11.88 8.915000000000001 2 PMID:10427692;PMID:6401702 -4.1.1.18 * serratia marcescens 179.0 179.0 1 PMID:33572696 -4.1.1.19 * avena sativa 0.0331 0.01715 2 PMID:19063883 -4.1.1.19 * brassica rapa subsp. oleifera 0.064 0.064 1 * -4.1.1.19 * chlamydia pneumoniae 8.1 8.1 1 PMID:17693492 -4.1.1.19 * chloroflexus aurantiacus 1.5 1.5 1 PMID:20876533 -4.1.1.19 * christiangramia forsetii 0.39 0.39 1 PMID:20876533 -4.1.1.19 * escherichia coli 410.0 2.8 7 PMID:19603287;PMID:4870599;PMID:6353148 -4.1.1.19 * glycine max 0.0096 0.0096 1 PMID:9399439 -4.1.1.19 * lathyrus sativus 1.495 1.495 1 PMID:1252 -4.1.1.19 * methanocaldococcus jannaschii 2.1 1.014 3 PMID:11980912;PMID:18391404 -4.1.1.19 * persea americana 0.0023 0.0023 1 PMID:16663805 -4.1.1.19 * pseudomonas sp. 0.113 0.113 1 PMID:1382 -4.1.1.19 * selenomonas ruminantium 14.94 0.03102 6 PMID:18256468 -4.1.1.19 * thermococcus kodakarensis 0.28 0.28 1 PMID:18702616 -4.1.1.2 * agrobacterium tumefaciens 6.567 6.567 1 PMID:18667852 -4.1.1.2 * atheliachaete sanguinea 15.0 15.0 1 * -4.1.1.2 * bacillus mojavensis 2.247 2.247 1 PMID:33321372 -4.1.1.2 * bacillus subtilis 83.0 30.0 7 PMID:11546787;PMID:17459326;PMID:21277974;PMID:23971028;PMID:30806021;PMID:32093895 -4.1.1.2 * dichomitus squalens 86.0 50.0 2 * -4.1.1.2 * pseudomonas sp. 154.0 154.0 1 PMID:35007451 -4.1.1.2 * trametes ochracea 9.0 9.0 1 * -4.1.1.2 * trametes versicolor 41.0 41.0 1 * -4.1.1.20 * butyrivibrio fibrisolvens 0.116 0.116 1 PMID:1295484 -4.1.1.20 * chlamydomonas sp. 0.01 0.01 1 PMID:7948877 -4.1.1.20 * clostridium spp. 0.209 0.209 1 PMID:1295484 -4.1.1.20 * escherichia coli 9.0 7.5 3 PMID:11856852 -4.1.1.20 * fibrobacter succinogenes 0.128 0.128 1 PMID:1295484 -4.1.1.20 * glycine max 0.017 0.017 1 PMID:7948877 -4.1.1.20 * lysinibacillus sphaericus 28.3 28.3 1 * -4.1.1.20 * megasphaera elsdenii 0.418 0.418 1 PMID:1295484 -4.1.1.20 * methylophilus methylotrophus 0.09 0.09 1 PMID:15277749 -4.1.1.20 * nicotiana tabacum 0.008 0.008 1 PMID:7948877 -4.1.1.20 * priestia megaterium 0.046 0.046 1 * -4.1.1.20 * pseudomonas aeruginosa 0.0156 0.0156 1 PMID:102088 -4.1.1.20 * selenomonas ruminantium 0.629 0.629 1 PMID:1295484 -4.1.1.20 * streptococcus equinus 0.091 0.091 1 PMID:1295484 -4.1.1.20 * thermotoga maritima 675.0 26.6 3 PMID:34258615 -4.1.1.20 * zea mays 0.048 0.048 1 PMID:7948877 -4.1.1.21 * ovis aries 42.75 42.75 1 PMID:1781372 -4.1.1.22 * clostridium perfringens 7.0 7.0 1 PMID:6294108 -4.1.1.22 * homo sapiens 0.0002 0.0002 1 PMID:17227057 -4.1.1.22 * klebsiella aerogenes 153.0 137.0 2 PMID:2033044;PMID:3114230 -4.1.1.22 * lactobacillus sp. 69.0 69.0 1 * -4.1.1.22 * morganella morganii 147.0 147.0 1 PMID:17220267 -4.1.1.22 * mus musculus 166.0 0.8 3 PMID:1540215;PMID:2118138;PMID:3718471 -4.1.1.22 * oenococcus oeni 17.26 17.26 1 PMID:9633629 -4.1.1.22 * photobacterium damselae 147.0 147.0 1 PMID:17220267 -4.1.1.22 * photobacterium phosphoreum 144.0 143.5 2 PMID:17220267 -4.1.1.22 * raoultella planticola 136.0 123.0 3 PMID:17220267;PMID:2033044;PMID:3114230 -4.1.1.22 * rattus norvegicus 1.4e-07 1.4e-07 1 PMID:10893046 -4.1.1.22 * staphylococcus epidermidis 32.75 32.75 1 * -4.1.1.22 * tetragenococcus muriaticus 1.6 1.6 1 PMID:12010554 -4.1.1.23 * escherichia coli 220.0 220.0 1 PMID:6355062 -4.1.1.23 * homo sapiens 0.0017 0.0017 1 PMID:1165245 -4.1.1.23 * plasmodium falciparum 10.0 7.8125 2 PMID:15147974;PMID:16754976 -4.1.1.23 * saccharomyces cerevisiae 90.0 37.65 6 PMID:10446147;PMID:11278904;PMID:357908;PMID:374408 -4.1.1.23 * sulfolobus acidocaldarius 12.4 6.2062 2 * -4.1.1.25 * eschscholzia californica 2.6 2.6 1 PMID:16666277 -4.1.1.25 * levilactobacillus brevis 1058.0 43.1 7 PMID:11167003;PMID:12052555;PMID:24211777;PMID:27292129 -4.1.1.25 * thalictrum rugosum 0.18 0.18 1 PMID:16666277 -4.1.1.28 * bacillus atrophaeus 2.6 2.6 1 PMID:33713143 -4.1.1.28 * bos taurus 8.9 0.88 4 PMID:1737055;PMID:2115615;PMID:3415655 -4.1.1.28 * calliphora vicina 11.32 11.32 1 PMID:1137393 -4.1.1.28 * catharanthus roseus 0.0015 0.00075 8 PMID:18587132 -4.1.1.28 * cavia porcellus 35.95 29.61 2 PMID:309771 -4.1.1.28 * drosophila melanogaster 4.07 4.07 1 * -4.1.1.28 * homo sapiens 10.03 1.840185 6 PMID:19041269;PMID:20535562;PMID:21479916 -4.1.1.28 * levilactobacillus brevis 43.1 22.55 2 * -4.1.1.28 * micrococcus percitreus 37.7 37.7 1 * -4.1.1.28 * rattus norvegicus 7.5 0.016259465 8 PMID:18602388;PMID:19167406;PMID:3119338;PMID:3584092;PMID:9367815 -4.1.1.28 * sus scrofa 3.069 2.851 3 PMID:436828;PMID:8374304 -4.1.1.29 * aedes aegypti 6.7 6.7 1 PMID:22685715 -4.1.1.29 * bos taurus 0.072 0.072 1 PMID:6956856 -4.1.1.29 * homo sapiens 4.89 4.25 2 PMID:22718265 -4.1.1.29 * rattus norvegicus 1.67 0.94 2 PMID:7215627 -4.1.1.29 * sus scrofa 0.772 0.505 2 PMID:11725125 -4.1.1.29 * tribolium castaneum 1.69 1.69 1 PMID:31696283 -4.1.1.31 * acetobacter aceti 15.9 15.9 1 * -4.1.1.31 * amaranthus hypochondriacus 54.0 54.0 1 * -4.1.1.31 * amaranthus viridis 17.1 17.1 1 PMID:24232027 -4.1.1.31 * ancylobacter novellus 51.09 51.09 1 PMID:1416912 -4.1.1.31 * arabidopsis thaliana 22.3 11.167 2 PMID:19923749 -4.1.1.31 * brachiaria hybrid cultivar 9.51 7.130000000000001 6 * -4.1.1.31 * brassica napus 37.2 37.2 1 PMID:10880970 -4.1.1.31 * brassica rapa subsp. oleifera 7.68 7.68 1 * -4.1.1.31 * chlamydomonas reinhardtii 18.11 9.0695 2 PMID:17888908;PMID:9512480 -4.1.1.31 * cicer arietinum 0.137 0.137 1 PMID:16664628 -4.1.1.31 * coccochloris peniocystis 8.87 8.87 1 PMID:3093461 -4.1.1.31 * corynebacterium glutamicum 23.7 23.7 1 PMID:28256782 -4.1.1.31 * echinochloa crus-galli 18.85 18.85 1 * -4.1.1.31 * escherichia coli 30.0 30.0 1 PMID:4560418 -4.1.1.31 * fagus sylvatica 0.1245 0.07615 4 PMID:17997763 -4.1.1.31 * glycine max 5.2 5.2 1 PMID:16667849 -4.1.1.31 * hydrilla verticillata 0.461 0.1005 16 PMID:16936335 -4.1.1.31 * hyphomicrobium methylovorum 104.0 104.0 1 * -4.1.1.31 * kalanchoe fedtschenkoi 26.0 21.0 3 PMID:1022554;PMID:3800979;PMID:743204 -4.1.1.31 * medicago sativa 42.3 42.3 1 PMID:16663590 -4.1.1.31 * methanothermus sociabilis 2.7 2.7 1 PMID:8772193 -4.1.1.31 * molinema dessetae 14.55 14.55 1 PMID:8479801 -4.1.1.31 * monoraphidium minutum 0.138 0.08700000000000001 2 PMID:16667617 -4.1.1.31 * nicotiana tabacum 28.5 28.5 1 PMID:8988646 -4.1.1.31 * oceanimonas smirnovii 21.8 21.8 1 PMID:26142903 -4.1.1.31 * oryza sativa 22.73 0.14 10 * -4.1.1.31 * phaeodactylum tricornutum 41.7 41.7 1 PMID:24835101 -4.1.1.31 * plasmodium berghei 1.5 1.5 1 PMID:4621631 -4.1.1.31 * pseudomonas aeruginosa 0.002 0.002 1 PMID:18996187 -4.1.1.31 * pseudomonas fluorescens 0.002 0.002 1 PMID:18996187 -4.1.1.31 * pyrococcus furiosus 0.0018 0.0018 1 * -4.1.1.31 * rhodopseudomonas sp. 48.6 48.6 1 * -4.1.1.31 * ricinus communis 29.2 24.7 4 PMID:12519778;PMID:19605358 -4.1.1.31 * saccharolobus solfataricus 2.1 2.1 1 PMID:15516590 -4.1.1.31 * streptomyces coelicolor 42.9 42.9 1 PMID:8328954 -4.1.1.31 * sulfolobus acidocaldarius 2.77 2.77 1 * -4.1.1.31 * symplocarpus renifolius 0.107 0.107 1 PMID:27739913 -4.1.1.31 * thermus sp. 29.4 29.4 1 PMID:8902615 -4.1.1.31 * thiobacillus thioparus 0.32 0.32 1 PMID:241472 -4.1.1.31 * triticum aestivum 0.15 0.023295 36 PMID:16878554 -4.1.1.31 * zea mays 23.58 20.9 4 PMID:2775222 -4.1.1.32 * acetivibrio thermocellus 4.14 4.14 1 PMID:23435896 -4.1.1.32 * aquarana catesbeiana 17.7 17.7 1 PMID:6970195 -4.1.1.32 * ascaris suum 2.93 2.93 1 PMID:3759946 -4.1.1.32 * gallus gallus 46.5 46.5 1 PMID:3782066 -4.1.1.32 * modiolus demissus 1.81 1.81 1 * -4.1.1.32 * mycolicibacterium smegmatis 43.0 29.4 3 PMID:17015450 -4.1.1.32 * oryctolagus cuniculus 14.5 14.0 2 PMID:3334872 -4.1.1.32 * ovis aries 4.75 4.75 1 PMID:5047708 -4.1.1.32 * perumytilus purpuratus 13.0 13.0 1 * -4.1.1.32 * rattus norvegicus 19.9 18.299999999999997 2 PMID:728402 -4.1.1.32 * saccharomyces cerevisiae 6.0 6.0 1 PMID:7947744 -4.1.1.32 * squalus acanthias 5.9 5.9 1 PMID:2369129 -4.1.1.33 * bacopa monnieri 36.7 36.7 1 PMID:26027607 -4.1.1.33 * gallus gallus 6.26 6.26 1 PMID:6814481 -4.1.1.33 * mus musculus 0.2327 0.2327 1 PMID:11913522 -4.1.1.33 * saccharomyces cerevisiae 6.4 6.4 3 PMID:15169949;PMID:15709780;PMID:20971863 -4.1.1.33 * staphylococcus epidermidis 8.6 8.6 1 PMID:25499551 -4.1.1.35 * hordeum vulgare 0.099 0.099 1 PMID:15849307 -4.1.1.35 * lathyrus oleraceus 3.02 2.4 2 PMID:12461125 -4.1.1.35 * lemna minor 4.98 4.98 1 PMID:240327 -4.1.1.35 * nicotiana tabacum 17.57 17.57 1 PMID:12453569 -4.1.1.36 * equus caballus 0.089 0.089 1 PMID:440105;PMID:4459135 -4.1.1.36 * escherichia coli 0.6 0.6 1 PMID:3307915 -4.1.1.36 * rattus norvegicus 0.03 0.03 1 PMID:6061681 -4.1.1.37 * bos taurus 0.016 0.016 1 PMID:6626522 -4.1.1.37 * cereibacter sphaeroides 0.0126 0.0126 1 PMID:8352737 -4.1.1.37 * gallus gallus 0.0237 0.0035 3 PMID:3702738;PMID:4984554;PMID:6403526 -4.1.1.37 * homo sapiens 7.6 0.17 5 PMID:1582524;PMID:18004775;PMID:6626181;PMID:6822570 -4.1.1.37 * saccharomyces cerevisiae 0.029 0.029 1 PMID:2180703 -4.1.1.38 * entamoeba histolytica 23.0 8.9 3 PMID:26269598 -4.1.1.39 * acidithiobacillus ferrooxidans 112.0 112.0 1 * -4.1.1.39 * acinetobacter sp. 39.5 39.5 1 PMID:9264026 -4.1.1.39 * allochromatium vinosum 6.7 6.405 2 PMID:2211708 -4.1.1.39 * alviniconcha hessleri 2.88 2.88 1 PMID:8180629 -4.1.1.39 * aphanothece halophytica 0.023 0.023 1 PMID:113034 -4.1.1.39 * chlorella sorokiniana 0.133 0.133 1 PMID:16664495 -4.1.1.39 * cupriavidus necator 1.56 1.56 1 PMID:1015944 -4.1.1.39 * cyanidium caldarium 0.023 0.023 1 PMID:113034 -4.1.1.39 * cynodon dactylon 1.83 1.8 4 PMID:20363871 -4.1.1.39 * glycine max 0.325 0.2475 2 * -4.1.1.39 * gossypium hirsutum 0.08 0.045 2 PMID:7410399 -4.1.1.39 * haloferax mediterranei 0.052 0.052 1 PMID:8174567 -4.1.1.39 * hydrogenophaga pseudoflava 304.3 304.3 1 PMID:9264026 -4.1.1.39 * medicago sativa 0.17 0.10500000000000001 2 PMID:7410399 -4.1.1.39 * nicotiana tabacum 0.19 0.105 2 PMID:7410399 -4.1.1.39 * nitrobacter winogradskyi 0.7 0.7 1 * -4.1.1.39 * paracoccus denitrificans 1.88 1.88 1 * -4.1.1.39 * paspalum dilatatum 2.14 2.07 4 PMID:20363871 -4.1.1.39 * rhodospirillum rubrum 6.0 6.0 1 PMID:6818424 -4.1.1.39 * solanum lycopersicum 0.08 0.05 2 PMID:7410399 -4.1.1.39 * solanum tuberosum 0.18 0.105 2 PMID:7410399 -4.1.1.39 * spinacia oleracea 2.83 1.3599999999999999 8 PMID:18709490;PMID:3963387;PMID:7410399 -4.1.1.39 * symphytum sp. 1.3 1.3 1 * -4.1.1.39 * thermochromatium tepidum 79.0 79.0 1 * -4.1.1.39 * thermococcus kodakarensis 19.8 19.8 1 PMID:9988755 -4.1.1.39 * thermosynechococcus vestitus 1.83 0.5 3 PMID:17922215 -4.1.1.39 * thiomicrospira thyasirae 0.85 0.85 1 PMID:7410399 -4.1.1.39 * trichormus variabilis 2.0 2.0 1 PMID:6772105 -4.1.1.39 * zea mays 2.36 1.2454999999999998 2 * -4.1.1.39 * zoysia japonica 2.39 2.05 4 PMID:20363871 -4.1.1.4 * paenibacillus polymyxa 296.0 296.0 1 * -4.1.1.40 * bos taurus 0.083 0.083 1 PMID:14186730 -4.1.1.43 * acinetobacter calcoaceticus 2.69 2.69 1 * -4.1.1.43 * acinetobacter sp. 0.67 0.67 1 * -4.1.1.43 * meyerozyma guilliermondii 0.045 0.045 1 PMID:57780 -4.1.1.45 * homo sapiens 3.54 0.8 5 PMID:15229365;PMID:17288562;PMID:25392945 -4.1.1.45 * pseudomonas fluorescens 6.0 2.9 5 PMID:16131206;PMID:16716073 -4.1.1.45 * rattus norvegicus 8.82 8.445 2 PMID:11802786 -4.1.1.45 * sus scrofa 3.789 3.789 1 PMID:8866254 -4.1.1.46 * aspergillus niger 22.0 15.9 3 PMID:3593354;PMID:6066253 -4.1.1.46 * aspergillus oryzae 5.2 5.2 1 PMID:8620029 -4.1.1.46 * cutaneotrichosporon cutaneum 14.5 14.5 1 PMID:7194334 -4.1.1.47 * escherichia coli 17.5 17.5 1 PMID:22970650 -4.1.1.47 * escherichia coli k-12 17.5 17.5 1 PMID:18176558 -4.1.1.48 * bacillus subtilis 3.7 3.7 1 PMID:110789 -4.1.1.48 * escherichia coli 69.0 69.0 1 PMID:5332729 -4.1.1.48 * euglena gracilis 1.8 1.8 1 PMID:401810 -4.1.1.48 * klebsiella aerogenes 3.2 3.2 1 PMID:4919415 -4.1.1.48 * mycobacterium tuberculosis 0.004 0.004 1 * -4.1.1.48 * pyrococcus furiosus 15.2 15.2 1 PMID:30264228 -4.1.1.48 * salmonella enterica subsp. enterica serovar typhimurium 2.3 2.3 1 PMID:11265469;PMID:4919415 -4.1.1.48 * serratia marcescens 300.0 300.0 1 PMID:4559725 -4.1.1.48 * thermotoga maritima 2.3 2.3 1 PMID:11265469;PMID:4919415 -4.1.1.49 * acetivibrio thermocellus 0.31 0.31 1 PMID:23435896 -4.1.1.49 * alternanthera pungens 40.5 40.5 1 * -4.1.1.49 * arabidopsis thaliana 6.0 4.5 2 PMID:31548269 -4.1.1.49 * leishmania major 69.6 60.599999999999994 2 PMID:26271440 -4.1.1.49 * trypanosoma brucei 81.8 81.8 1 PMID:7766679 -4.1.1.49 * trypanosoma cruzi 1265.0 1265.0 1 * -4.1.1.5 * enterobacter cloacae 1024.37 1024.37 1 PMID:35558320 -4.1.1.5 * klebsiella aerogenes 849.08 849.08 1 PMID:31000168 -4.1.1.5 * lactococcus lactis 454.3 454.3 1 PMID:8076701 -4.1.1.5 * streptococcus thermophilus 0.472 0.371 2 PMID:12753249 -4.1.1.50 * acanthamoeba castellanii 0.158 0.158 1 PMID:8216217 -4.1.1.50 * caenorhabditis elegans 0.0005 0.0005 1 PMID:12674502 -4.1.1.50 * escherichia coli 0.88 0.88 1 PMID:6353153 -4.1.1.50 * glycine max 0.00126 0.00126 1 PMID:1764068 -4.1.1.50 * homo sapiens 410.0 152.0 7 PMID:12974388;PMID:1637820 -4.1.1.50 * mus musculus 0.102 0.102 1 PMID:117828 -4.1.1.50 * onchocerca volvulus 79.0 19.0 7 PMID:12974388 -4.1.1.50 * plasmodium falciparum 0.14 0.114 2 PMID:21803076 -4.1.1.50 * rattus norvegicus 0.63 0.398 2 PMID:4455223;PMID:6621387 -4.1.1.50 * saccharolobus solfataricus 0.11 0.061 2 PMID:1649051;PMID:18650422 -4.1.1.50 * saccharomyces cerevisiae 0.106 0.106 1 PMID:6312267 -4.1.1.52 * penicillium griseofulvum 11.6 11.6 1 PMID:237216 -4.1.1.53 * enterococcus faecalis 0.0054 0.0054 1 * -4.1.1.53 * micrococcus percitreus 0.93 0.93 1 * -4.1.1.53 * phaseolus vulgaris 0.0015 0.00115 2 * -4.1.1.53 * rattus norvegicus 8444.0 1813.0 3 PMID:9367815 -4.1.1.55 * comamonas testosteroni 58.9 58.9 1 PMID:29563 -4.1.1.55 * pseudomonas fluorescens 4.8 4.8 1 PMID:3920963 -4.1.1.57 * crypthecodinium cohnii 4.45 2.2355 2 * -4.1.1.57 * dryopteris filix-mas 20.0 20.0 1 PMID:2271523 -4.1.1.57 * streptomyces sp. 29.7 28.85 2 PMID:2271525 -4.1.1.57 * streptomyces sp. 590 ki-2014 9.0 9.0 1 PMID:28003434 -4.1.1.58 * clonostachys rosea 196.8 196.8 1 * -4.1.1.58 * lasallia pustulata 14.1 14.1 1 PMID:5128738 -4.1.1.59 * blastobotrys adeninivorans 5.9 5.9 1 PMID:28966611 -4.1.1.59 * pantoea agglomerans 150.0 150.0 1 PMID:9835557 -4.1.1.61 * bacillus subtilis 31.0 15.5 10 PMID:18388975 -4.1.1.61 * chlamydia pneumoniae 0.00506 0.0026550000000000002 2 PMID:17211544 -4.1.1.61 * enterobacter cloacae 17.8 15.75 2 PMID:16758158 -4.1.1.61 * pseudomonas sp. 0.012 0.012 1 PMID:1592817 -4.1.1.61 * sedimentibacter hydroxybenzoicus 8.29 8.29 1 PMID:7744052 -4.1.1.61 * uncultured bacterium 766.0 766.0 1 PMID:11006847 -4.1.1.63 * sedimentibacter hydroxybenzoicus 20.6 20.6 1 PMID:8655551 -4.1.1.64 * burkholderia cepacia 8.8 5.615 2 PMID:2180928;PMID:5140194 -4.1.1.64 * fusarium solani 3.2 3.2 1 * -4.1.1.65 * escherichia coli 55.0 52.0 2 PMID:1495415;PMID:4598120;PMID:7024734 -4.1.1.65 * mus musculus 0.0035 0.0035 1 * -4.1.1.65 * rattus norvegicus 0.032 0.032 1 PMID:1495416 -4.1.1.68 * escherichia coli 45.0 45.0 1 PMID:8223600 -4.1.1.7 * pseudomonas putida 193.0 77.4 4 PMID:1622241;PMID:18239944;PMID:3179267;PMID:7663351 -4.1.1.72 * bacillus subtilis 0.02 0.02 1 PMID:3142877 -4.1.1.72 * lactococcus lactis subsp. lactis 80.7 80.7 1 PMID:15358422 -4.1.1.73 * pseudomonas sp. 4.8 4.8 1 PMID:1778975 -4.1.1.74 * azospirillum brasilense 2.3 0.6205 8 PMID:17952626 -4.1.1.76 * achromobacter sp. 380.0 190.36 2 PMID:18023797 -4.1.1.76 * bordetella bronchiseptica 467.0 398.0 3 PMID:1369144;PMID:1459132 -4.1.1.76 * enterobacter cloacae 381.0 381.0 1 PMID:18283449 -4.1.1.77 * bordetella sp. 18.0 9.025 2 PMID:17090920 -4.1.1.78 * pseudomonas sp. 463.0 463.0 1 PMID:13575441 -4.1.1.8 * cupriavidus oxalaticus 44.8 44.8 1 PMID:14101969 -4.1.1.80 * berberis stolonifera 0.001271 0.001271 1 * -4.1.1.83 * clostridioides difficile 0.315 0.315 1 PMID:11231288 -4.1.1.84 * homo sapiens 100.0 100.0 1 PMID:9480844 -4.1.1.84 * rattus norvegicus 0.5 0.5 1 PMID:8267597 -4.1.1.86 * acinetobacter baumannii 0.012 0.010450000000000001 2 PMID:7550102;PMID:7813892 -4.1.1.86 * acinetobacter calcoaceticus 17.2 0.76 3 PMID:1512577;PMID:1804559;PMID:7550102 -4.1.1.86 * citrobacter freundii 0.0022 0.0022 1 PMID:8913500 -4.1.1.86 * enterobacter cloacae 0.0052 0.0052 1 PMID:8913500 -4.1.1.86 * klebsiella aerogenes 11.8 1.2 3 PMID:8913500 -4.1.1.86 * klebsiella oxytoca 0.0042 0.0042 1 PMID:8913500 -4.1.1.86 * klebsiella pneumoniae 0.0071 0.0071 1 PMID:8913500 -4.1.1.86 * pantoea agglomerans 0.0039 0.0039 1 PMID:8913500 -4.1.1.86 * salinivibrio costicola 0.0014 0.0014 1 * -4.1.1.86 * serratia liquefaciens 0.00392 0.00392 1 PMID:8913500 -4.1.1.86 * serratia marcescens 3.9 1.95255 2 PMID:8913500 -4.1.1.86 * vibrio alginolyticus 29.5 16.855 2 PMID:2614383 -4.1.1.86 * vibrio anguillarum 0.00036 0.00036 1 * -4.1.1.86 * vibrio cholerae serotype o1 0.00071 0.00071 1 * -4.1.1.86 * vibrio proteolyticus 0.0011 0.0011 1 * -4.1.1.87 * acinetobacter calcoaceticus 0.19 0.19 1 PMID:10561613 -4.1.1.88 * acinetobacter calcoaceticus 10.02 10.02 1 * -4.1.1.88 * pseudomonas fluorescens 4.48 4.48 1 * -4.1.1.9 * aix sponsa 83.0 83.0 1 PMID:102255;PMID:6792462 -4.1.1.9 * anser sp. 74.0 74.0 1 PMID:6792462;PMID:827976 -4.1.1.9 * bos taurus 206.0 206.0 1 PMID:4731972 -4.1.1.9 * cairina moschata 80.3 80.3 1 PMID:102255;PMID:6792462 -4.1.1.9 * mycobacterium tuberculosis 2.396 2.396 1 PMID:114118;PMID:6792462 -4.1.1.9 * rattus norvegicus 43.4 16.46 3 PMID:101148;PMID:12297032;PMID:6792462;PMID:718970 -4.1.1.9 * saccharopolyspora erythraea 0.6 0.6 1 PMID:6422856 -4.1.1.90 * homo sapiens 2.7e-06 2.7e-06 1 PMID:17073445 -4.1.1.91 * cutaneotrichosporon moniliiforme 0.47 0.47 1 PMID:20188702 -4.1.1.92 * glutamicibacter nicotianae 0.224 0.224 1 PMID:12506977 -4.1.1.94 * mus musculus 8800.0 8800.0 1 PMID:22016388 -4.1.1.96 * eshraghiella crossota 12.8 12.8 1 PMID:35931895 -4.1.1.96 * vibrio alginolyticus 24.1 0.023 3 PMID:7812450 -4.1.2.10 * arabidopsis thaliana 133.6 13.3 5 PMID:22378361;PMID:33044692 -4.1.2.10 * chamberlinius hualienensis 7420.0 7420.0 1 PMID:26261304 -4.1.2.10 * davallia tyermanii 290.0 290.0 1 PMID:29131473 -4.1.2.10 * eriobotrya japonica 40.9 40.9 1 PMID:18540101 -4.1.2.10 * granulicella tundricola 1.74 1.74 1 PMID:23981508 -4.1.2.10 * passiflora edulis 136.0 133.8 4 PMID:25919621;PMID:27914120 -4.1.2.10 * prunus armeniaca 141.0 141.0 1 * -4.1.2.10 * prunus mume 220.0 129.0 5 PMID:21307605 -4.1.2.10 * prunus pedunculata 661.0 661.0 1 PMID:29890248 -4.1.2.11 * sorghum bicolor 270.0 227.0 3 PMID:1487519;PMID:5922969 -4.1.2.13 * archaeoglobus fulgidus 0.01 0.01 1 PMID:11702074 -4.1.2.13 * ascaris suum 10.7 10.7 1 PMID:7154952 -4.1.2.13 * bacillus subtilis 32.3 11.024999999999999 4 PMID:6818420 -4.1.2.13 * bos taurus 25.5 12.05 6 PMID:10050044;PMID:19072 -4.1.2.13 * ceratitis capitata 11.0 10.95 2 PMID:28092 -4.1.2.13 * chara vulgaris 4.8 4.0 2 PMID:16666130 -4.1.2.13 * echinococcus multilocularis 67.42 67.42 1 PMID:35051088 -4.1.2.13 * euglena gracilis 22.0 21.0 2 PMID:12232396 -4.1.2.13 * gracilariopsis chorda 10.7 5.411499999999999 2 * -4.1.2.13 * haloarcula vallismortis 38.4 38.4 1 PMID:1900049 -4.1.2.13 * haloferax mediterranei 2.8 2.8 1 PMID:12501417 -4.1.2.13 * homo sapiens 22.3 8.535 4 PMID:12417303;PMID:14766013;PMID:7154951;PMID:889843 -4.1.2.13 * lathyrus oleraceus 2.0 2.0 1 PMID:1155947 -4.1.2.13 * leishmania mexicana 37.0 37.0 1 PMID:10551371 -4.1.2.13 * lethenteron camtschaticum 18.5 12.14 4 PMID:9143366 -4.1.2.13 * methanococcus maripaludis 0.044 0.044 1 PMID:8288525 -4.1.2.13 * moritella marina 44.29 44.29 1 PMID:39385 -4.1.2.13 * mycobacterium tuberculosis 35.1 35.05 3 PMID:15294302 -4.1.2.13 * nephropidae 14.8 14.8 1 PMID:1134354;PMID:237182 -4.1.2.13 * nocardia asteroides 568.0 568.0 1 * -4.1.2.13 * oryctolagus cuniculus 28.0 28.0 1 PMID:743202 -4.1.2.13 * peptoniphilus asaccharolyticus 14.8 14.8 1 PMID:1134354;PMID:237182 -4.1.2.13 * phaseolus vulgaris 29.86 29.86 1 * -4.1.2.13 * pyricularia grisea 70.3 40.9 2 PMID:16901716 -4.1.2.13 * pyrobaculum calidifontis 1.32 1.31 2 PMID:28299451 -4.1.2.13 * ricinus communis 2.5 2.5 1 PMID:9675026 -4.1.2.13 * spinacia oleracea 7.8 7.18 3 PMID:6617652 -4.1.2.13 * staphylococcus carnosus 26.7 12.2 3 * -4.1.2.13 * synechococcus elongatus pcc 7942 = fachb-805 128.0 128.0 1 * -4.1.2.13 * synechocystis sp. 8.62 8.195 2 PMID:12668779 -4.1.2.13 * thermus aquaticus 160.0 103.0 2 PMID:11237691;PMID:8898912 -4.1.2.13 * trachemys scripta elegans 22.8 22.8 1 PMID:23874782 -4.1.2.13 * vigna radiata 15.1 15.1 1 PMID:15896364 -4.1.2.13 * zea mays 6.4 3.35 2 PMID:6617652 -4.1.2.14 * azotobacter vinelandii 625.0 625.0 1 PMID:8166720 -4.1.2.14 * pseudomonas putida 330.0 285.0 2 PMID:5555561 -4.1.2.14 * thermotoga maritima 9.4 9.4 1 PMID:11814840 -4.1.2.14 * zymomonas mobilis 600.0 600.0 1 PMID:6326622 -4.1.2.17 * escherichia coli 10.0 5.00425 2 PMID:11732896 -4.1.2.17 * methanocaldococcus jannaschii 0.0256 0.019450000000000002 2 PMID:22418259 -4.1.2.18 * pseudomonas sp. 1.63 1.395 2 PMID:237185;PMID:5016652;PMID:7154955 -4.1.2.19 * escherichia coli 17.2 4.2 7 PMID:14243785;PMID:4975916;PMID:7582972 -4.1.2.20 * escherichia coli 180.0 180.0 1 * -4.1.2.20 * picrophilus oshimae 48.0 24.07 2 PMID:20023024 -4.1.2.21 * roseateles saccharophilus 132.0 132.0 1 * -4.1.2.22 * bifidobacterium animalis subsp. lactis 4.28 4.28 1 PMID:11292814 -4.1.2.22 * bifidobacterium dentium 30.0 30.0 1 PMID:1085128 -4.1.2.22 * bifidobacterium longum 14.6 14.6 1 PMID:11298932 -4.1.2.22 * bifidobacterium pseudolongum subsp. globosum 24.0 24.0 1 PMID:1085128 -4.1.2.22 * komagataeibacter xylinus 0.267 0.267 1 PMID:13610828 -4.1.2.22 * lactiplantibacillus paraplantarum 147.3 76.75 2 PMID:18051305 -4.1.2.25 * escherichia coli 8.7 4.3519499999999995 2 PMID:4912541;PMID:6990196;PMID:9651328 -4.1.2.26 * pseudomonas putida 300.0 38.68 4 PMID:16085854;PMID:31152342 -4.1.2.32 * dosidicus gigas 159.0 79.595 2 PMID:16448210 -4.1.2.34 * nocardioides sp. 11.5 11.5 1 PMID:9473051 -4.1.2.34 * uncultured bacterium 0.12 0.029 3 PMID:6833175 -4.1.2.35 * saccharomyces cerevisiae 0.91 0.91 1 * -4.1.2.38 * pseudomonas fluorescens 11690.0 5.995 4 PMID:19209447;PMID:19224568;PMID:2496105 -4.1.2.4 * aeropyrum pernix 4.5 4.5 1 PMID:12529358 -4.1.2.4 * escherichia coli 189.0 189.0 1 * -4.1.2.4 * haemophilus influenzae 34.1 34.1 1 * -4.1.2.4 * homo sapiens 0.07 0.07 1 PMID:4989681 -4.1.2.4 * hyperthermus butylicus 0.5 0.35 2 * -4.1.2.4 * klebsiella pneumoniae 2.5 2.5 1 PMID:12839746 -4.1.2.4 * paenibacillus sp. 62.0 53.0 2 PMID:20622498 -4.1.2.4 * pyrobaculum aerophilum 58.0 29.125 2 PMID:17905878 -4.1.2.4 * rattus norvegicus 1.775 1.775 1 PMID:6016328 -4.1.2.4 * salmonella enterica subsp. enterica serovar typhimurium 58.3 56.65 2 PMID:237187;PMID:4879701 -4.1.2.4 * thermococcus kodakarensis 285.0 285.0 1 PMID:15205420 -4.1.2.4 * thermotoga maritima 1.0 1.0 1 PMID:17905878 -4.1.2.4 * yersinia sp. ea015 137.0 96.5 2 PMID:19505577 -4.1.2.40 * klebsiella pneumoniae 3.07 3.07 1 PMID:6759854 -4.1.2.40 * lactococcus cremoris 32.2 32.2 1 PMID:6807956 -4.1.2.40 * staphylococcus aureus 19.5 19.5 1 PMID:7154949 -4.1.2.42 * achromobacter xylosoxidans 38.6 20.3 2 PMID:10952004;PMID:33015743 -4.1.2.42 * arthrobacter sp. 35.7 35.7 1 PMID:9642221 -4.1.2.42 * chlamydomonas reinhardtii 7.05 7.05 1 PMID:28038776 -4.1.2.42 * delftia sp. 21.3 21.3 1 * -4.1.2.43 * [aminomonas] aminovorus 20.0 20.0 1 PMID:15280650 -4.1.2.43 * acidomonas methanolica 64.0 32.7 2 PMID:2280713 -4.1.2.43 * bacillus sp. (in: firmicutes) 64.0 33.75 2 PMID:2280711 -4.1.2.43 * methanosarcina barkeri 4.4 4.4 1 PMID:16075199 -4.1.2.43 * methylococcus capsulatus 69.0 35.355 2 PMID:4219834 -4.1.2.43 * methylomonas aminofaciens 52.0 27.65 2 PMID:564713 -4.1.2.43 * methylomonas sp. 4100.0 46.25 4 * -4.1.2.43 * mycobacterium gastri 74.2 56.0 4 PMID:17520247;PMID:2280712 -4.1.2.43 * pyrococcus horikoshii 235.0 145.85 2 PMID:15901685 -4.1.2.43 * thermococcus kodakarensis 148.0 78.9 2 PMID:16788179 -4.1.2.44 * aromatoleum evansii 4.9 4.9 1 PMID:15916608 -4.1.2.45 * pseudomonas putida 1.55 1.55 1 PMID:1447127 -4.1.2.45 * sphingobium xenophagum 23.67 23.67 1 PMID:8486638 -4.1.2.45 * sphingomonas paucimobilis 11.0 9.35 2 PMID:10731665 -4.1.2.46 * linum usitatissimum 52.9 43.5 2 PMID:3377504;PMID:8387315 -4.1.2.47 * baliospermum montanum 178.0 110.2 2 PMID:21352863 -4.1.2.47 * hevea brasiliensis 86.9 33.0 3 PMID:25044660 -4.1.2.47 * manihot esculenta 250.0 47.5 13 PMID:12889812;PMID:18633988;PMID:21185385;PMID:8824213;PMID:8900417;PMID:8958123;PMID:9536038 -4.1.2.48 * candida albicans 8.5 8.5 1 PMID:10641038 -4.1.2.48 * escherichia coli 1.7 1.7 1 PMID:9692922 -4.1.2.48 * pseudomonas sp. 41.0 41.0 1 PMID:9464392 -4.1.2.48 * saccharomyces cerevisiae 2.5 2.5 1 PMID:9151955 -4.1.2.48 * vanrija humicola 2.91 2.91 2 PMID:5017702;PMID:5438301 -4.1.2.49 * aeromonas jandaei 217.0 45.2 5 PMID:9171400;PMID:9228760 -4.1.2.51 * picrophilus oshimae 48.0 48.0 1 PMID:20023024 -4.1.2.53 * escherichia coli 60.0 60.0 1 PMID:34589311 -4.1.2.61 * pseudomonas fluorescens 0.003 0.003 1 PMID:10222033 -4.1.2.63 * homo sapiens 500.0 500.0 1 PMID:21708296 -4.1.2.9 * bifidobacterium animalis subsp. lactis 4.28 4.28 1 PMID:11292814 -4.1.2.9 * clostridium acetobutylicum 21.0 6.9 3 PMID:22865845;PMID:22922942 -4.1.2.9 * debaryomyces hansenii 0.591 0.3715 2 * -4.1.2.9 * lactiplantibacillus pentosus 4.455 4.455 1 PMID:11823225 -4.1.2.9 * lactiplantibacillus plantarum 0.61 0.2 3 PMID:18430452 -4.1.2.9 * leuconostoc mesenteroides 9.9 9.9 1 * -4.1.2.9 * oenococcus oeni 2.3 1.222 2 PMID:8391532 -4.1.3.1 * acinetobacter calcoaceticus 2.9 2.9 1 PMID:1938889;PMID:236948;PMID:687365 -4.1.3.1 * amaranthus caudatus 0.48 0.0325 4 PMID:25955696 -4.1.3.1 * aspergillus fumigatus 8.4 4.3100000000000005 2 PMID:16603391 -4.1.3.1 * aspergillus nidulans 11.0 11.0 1 * -4.1.3.1 * bacillus sp. (in: firmicutes) 2.9 2.9 1 PMID:1938889;PMID:236948;PMID:687365 -4.1.3.1 * candida brassicae 8.01 8.01 1 * -4.1.3.1 * candida tropicalis 9.9 9.350000000000001 2 * -4.1.3.1 * chlamydomonas reinhardtii 9.5 9.5 1 PMID:19847013 -4.1.3.1 * citrullus lanatus 16.1 16.1 1 * -4.1.3.1 * colwellia maris 14.6 6.17 3 PMID:11440123;PMID:12382116;PMID:15470117 -4.1.3.1 * debaryomyces hansenii 0.005 0.0048 3 PMID:18752629 -4.1.3.1 * escherichia coli 54.0 0.5045 20 PMID:15470117;PMID:15748982;PMID:3281659 -4.1.3.1 * euglena gracilis 5.19 2.9130000000000003 2 PMID:15964777 -4.1.3.1 * fomitopsis palustris 30.3 30.3 1 PMID:11888209 -4.1.3.1 * geobacillus stearothermophilus 2.9 2.9 1 PMID:1938889;PMID:236948;PMID:687365 -4.1.3.1 * glycine max 9.48 5.81 3 PMID:20198926 -4.1.3.1 * hyphomicrobium methylovorum 2.4 2.4 1 PMID:9395332 -4.1.3.1 * lupinus sp. 3.68 2.755 2 PMID:509354 -4.1.3.1 * mycobacterium tuberculosis 1.3 1.3 1 PMID:10572116 -4.1.3.1 * neurospora crassa 16.0 16.0 1 PMID:4278771 -4.1.3.1 * paecilomyces variotii 103.0 103.0 1 * -4.1.3.1 * papilio machaon 5.5 5.5 1 PMID:15170371 -4.1.3.1 * paracoccidioides brasiliensis 3.85 3.85 1 PMID:21535474 -4.1.3.1 * pinus pinea 10.1 10.1 1 PMID:3947071 -4.1.3.1 * pinus taeda 4.45 4.45 1 * -4.1.3.1 * prescottella equi 0.586 0.362 2 PMID:11882714;PMID:16177351 -4.1.3.1 * pseudomonas fluorescens 0.053 0.032 2 PMID:15094395 -4.1.3.1 * pseudomonas putida 0.321 0.182 2 PMID:10698750 -4.1.3.1 * rhodopseudomonas sp. 8.73 8.73 1 * -4.1.3.1 * ricinus communis 2.7 2.7 1 PMID:6805438 -4.1.3.1 * sinorhizobium meliloti 0.138 0.138 1 PMID:17526694 -4.1.3.1 * streptomyces clavuligerus 2.23 2.23 1 PMID:11750062 -4.1.3.1 * sulfolobus acidocaldarius 7.9 7.9 1 PMID:11904155 -4.1.3.1 * yarrowia lipolytica 7.4 7.4 1 * -4.1.3.1 * zea mays 4.96 4.65 4 PMID:1637186;PMID:19538126 -4.1.3.16 * bos taurus 9.7 9.23 5 PMID:1134356;PMID:1587831;PMID:5580656 -4.1.3.16 * homo sapiens 15.8 15.8 1 PMID:22771891 -4.1.3.16 * rattus norvegicus 8.0 6.3 4 PMID:14089442;PMID:3966804 -4.1.3.17 * arachis hypogaea 134.0 134.0 1 PMID:13976791 -4.1.3.17 * phytopseudomonas straminea 870.0 461.3 2 PMID:11826967;PMID:2229033 -4.1.3.17 * pseudomonas putida 67.0 52.35 2 PMID:20843800;PMID:7154956 -4.1.3.22 * geobacter sulfurreducens 0.0074 0.0074 1 PMID:18245290 -4.1.3.22 * leptospira biflexa 39.42 36.28 2 PMID:17227461 -4.1.3.22 * leptospira interrogans 82.36 53.68 7 PMID:17227461 -4.1.3.22 * leptospira meyeri 80.92 80.92 1 PMID:17227461 -4.1.3.24 * cereibacter sphaeroides 20.0 9.25 4 PMID:20047909 -4.1.3.24 * chloroflexus aurantiacus 6.5 1.4 4 PMID:12374834 -4.1.3.24 * methylorubrum extorquens 28.1 28.1 1 * -4.1.3.24 * pseudomonas sp. 0.47 0.47 1 PMID:4745770 -4.1.3.24 * rhodobacter capsulatus 37.0 18.0 3 PMID:15687206 -4.1.3.27 * catharanthus roseus 0.0262 0.00195 4 PMID:19031426 -4.1.3.27 * claviceps sp. 0.585 0.585 1 PMID:875641 -4.1.3.27 * escherichia coli 2.6 2.6 1 PMID:5333199 -4.1.3.27 * euglena gracilis 7.8 7.8 1 PMID:826535 -4.1.3.27 * mycobacterium tuberculosis 5.2 4.44 3 PMID:18952181 -4.1.3.27 * ogataea henricii 43.0 43.0 1 * -4.1.3.27 * pseudomonas putida 17.0 17.0 1 PMID:3600373 -4.1.3.27 * salmonella enterica subsp. enterica serovar typhimurium 0.384 0.384 1 PMID:4878701 -4.1.3.27 * serratia marcescens 4.5 4.5 1 PMID:5001612 -4.1.3.3 * clostridium perfringens 11.36 10.68 2 PMID:10763805;PMID:11432751 -4.1.3.3 * escherichia coli 56.8 12.3 10 PMID:13811398;PMID:1458058;PMID:1646603;PMID:19707758;PMID:6389524;PMID:8694758 -4.1.3.3 * lactiplantibacillus plantarum 7.65 7.65 1 PMID:21317263 -4.1.3.3 * staphylococcus aureus 11.0 6.0 3 PMID:23418011;PMID:23519810 -4.1.3.3 * staphylococcus carnosus 12.7 12.7 1 PMID:22803763 -4.1.3.3 * sus scrofa 36.26 0.96 4 PMID:10737328;PMID:10763805;PMID:19707758 -4.1.3.30 * aspergillus fumigatus 32.33 32.33 1 PMID:21453403 -4.1.3.30 * aspergillus nidulans 91.0 56.2 2 PMID:11422389 -4.1.3.30 * yarrowia lipolytica 1.76 0.8985 2 * -4.1.3.34 * hydrogenobacter thermophilus 280.0 33.0 3 PMID:15101982 -4.1.3.39 * pseudomonas putida 0.015 0.015 1 PMID:7496535 -4.1.3.39 * pseudomonas sp. 4.2 4.2 1 PMID:8419288 -4.1.3.4 * anas sp. 351.0 351.0 1 PMID:6159358 -4.1.3.4 * bos taurus 1.3 1.3 1 * -4.1.3.4 * homo sapiens 249.0 136.0 11 PMID:12464283;PMID:16601870;PMID:17459752;PMID:20558737;PMID:21514269;PMID:22865860;PMID:2450702;PMID:8027038;PMID:8670134 -4.1.3.4 * pseudomonas sp. 'mevalonii' 80.0 75.0 2 PMID:10989426;PMID:1332752;PMID:7632692 -4.1.3.4 * raphanus sativus 0.0098 0.0098 1 * -4.1.3.4 * sus scrofa 7.0 7.0 1 PMID:13271348 -4.1.3.41 * paracoccus denitrificans 99.0 20.0 9 PMID:12835921 -4.1.3.42 * azotobacter vinelandii 4.8 4.8 1 PMID:8166720 -4.1.3.42 * escherichia coli 96.7 7.9 5 PMID:1339418;PMID:4560498 -4.1.3.46 * chloroflexus aurantiacus 1.52 1.5 3 PMID:16952935;PMID:17259315 -4.1.3.6 * enterococcus faecalis 90.0 90.0 1 PMID:825122 -4.1.3.6 * escherichia coli 0.12 0.12 1 PMID:6354265 -4.1.3.6 * faecalispora sporosphaeroides 34.1 34.1 1 PMID:3994485 -4.1.3.6 * klebsiella pneumoniae 8.0 0.09 3 PMID:10924139 -4.1.3.6 * lacrimispora sphenoides 0.06 0.06 1 * -4.1.3.6 * lactococcus lactis subsp. lactis 0.2 0.2 1 * -4.1.3.6 * pyrobaculum islandicum 0.025 0.009 3 PMID:16740941 -4.1.3.6 * rubrivivax gelatinosus 138.8 69.58000000000001 2 PMID:4141604 -4.1.99.1 * aeromonas hydrophila 13.3 13.3 1 * -4.1.99.1 * escherichia coli 50.0 0.818 9 PMID:19657572;PMID:21081107;PMID:3298983;PMID:8534987 -4.1.99.1 * fusobacterium necrophorum subsp. funduliforme 12.5 12.5 1 PMID:236027 -4.1.99.1 * klebsiella aerogenes 16.7 16.7 1 PMID:8534987 -4.1.99.1 * photobacterium profundum 10.0 10.0 1 PMID:21081107 -4.1.99.1 * providencia rettgeri 9.01 5.7 2 PMID:1148216 -4.1.99.1 * symbiobacterium thermophilum 7.6 7.6 1 PMID:1368766 -4.1.99.1 * vibrio sp. 9.24 9.24 1 PMID:42371 -4.1.99.11 * azoarcus sp. 0.017 0.01 2 PMID:10483734;PMID:23935041 -4.1.99.11 * desulfosarcina cetonica 0.004 0.004 1 PMID:23935041 -4.1.99.11 * desulfotomaculum 0.016 0.016 1 PMID:11097937 -4.1.99.11 * geobacter metallireducens 0.015 0.015 1 PMID:23935041 -4.1.99.11 * methanospirillum sp. 0.016 0.016 1 PMID:11097937 -4.1.99.11 * methanothrix sp. 0.016 0.016 1 PMID:11097937 -4.1.99.11 * thauera aromatica 0.0195 0.0049 4 PMID:17105211;PMID:23935041;PMID:9632263 -4.1.99.12 * candida albicans 0.332 0.332 1 PMID:15328619 -4.1.99.12 * escherichia coli 0.152 0.152 1 PMID:10103033 -4.1.99.12 * escherichia coli k-12 0.283 0.283 1 PMID:9211332 -4.1.99.12 * methanocaldococcus jannaschii 0.174 0.174 1 PMID:12200440 -4.1.99.12 * meyerozyma guilliermondii 14.0 14.0 1 PMID:2246238 -4.1.99.12 * streptococcus pneumoniae 0.109 0.109 1 PMID:23954596 -4.1.99.14 * clostridium acetobutylicum 0.0071 0.0071 2 PMID:20405152 -4.1.99.14 * geobacillus stearothermophilus 2.6 2.6 1 PMID:16968710 -4.1.99.2 * aeromonas phenologenes 2.8 2.8 1 PMID:16345185 -4.1.99.2 * citrobacter freundii 10.0 0.08 9 PMID:19585534;PMID:21104284;PMID:24022778;PMID:7744078 -4.1.99.2 * citrobacter intermedius 1.94 1.295 2 PMID:5057881;PMID:7262088 -4.1.99.2 * pantoea agglomerans 3.9 0.513 5 PMID:19585534;PMID:8663898 -4.1.99.2 * pseudomonas putida 0.0232 0.0078 3 PMID:17993537 -4.1.99.2 * symbiobacterium thermophilum 8.133 8.133 1 * -4.1.99.2 * symbiobacterium toebii 1.25 0.55 3 * -4.1.99.5 * botryococcus braunii 0.00353 0.00353 1 PMID:1608940 -4.1.99.5 * lathyrus oleraceus 0.000235 0.000235 1 PMID:10845712 -4.2.1.1 * acipenser gueldenstaedtii 26970.0 26970.0 1 PMID:21381885 -4.2.1.1 * anguilla anguilla 7313.0 7313.0 1 PMID:11807116 -4.2.1.1 * bacillus subtilis 737.8 369.71 2 * -4.2.1.1 * bos taurus 74.6 7.843 3 * -4.2.1.1 * chionodraco hamatus 52410.0 52410.0 1 PMID:11807116 -4.2.1.1 * cyprinus carpio 375.3 375.3 1 PMID:15146348 -4.2.1.1 * dicentrarchus labrax 751.7 751.7 1 PMID:21787732 -4.2.1.1 * dunaliella salina 0.161 0.161 1 PMID:12651119 -4.2.1.1 * haematococcus lacustris 75.2 62.32 3 * -4.2.1.1 * homo sapiens 7.02 3.675 2 PMID:35638720 -4.2.1.1 * lathyrus oleraceus 14.5 14.5 1 PMID:16223737 -4.2.1.1 * mesorhizobium loti 1914000.0 1099500.0 2 PMID:19218391 -4.2.1.1 * micrococcus luteus 61.0 61.0 1 PMID:22112959 -4.2.1.1 * micrococcus lylae 66.5 66.5 1 PMID:22112959 -4.2.1.1 * micropterus salmoides 529.1 529.1 1 PMID:15146348 -4.2.1.1 * oncorhynchus mykiss 984.2 500.45000000000005 2 PMID:15146348 -4.2.1.1 * pseudomonas fragi 70.6 70.6 1 PMID:22112959 -4.2.1.1 * sander vitreus 455.4 455.4 1 PMID:15146348 -4.2.1.1 * trematomus bernacchii 25780.0 25780.0 1 PMID:11807116 -4.2.1.10 * acetivibrio clariflavus 117.89 117.89 1 PMID:25852984 -4.2.1.10 * alcanivorax borkumensis 34.72 34.72 1 PMID:25852984 -4.2.1.10 * alicyclobacillus acidocaldarius 195.8 195.8 1 PMID:25852984 -4.2.1.10 * aspergillus nidulans 1284.0 1284.0 1 PMID:1329726 -4.2.1.10 * bacillus subtilis 62.27 62.27 1 PMID:25852984 -4.2.1.10 * citrobacter koseri 93.91 93.91 1 PMID:25852984 -4.2.1.10 * corynebacterium glutamicum 119.14 119.14 1 PMID:25852984 -4.2.1.10 * crystallibacter crystallopoietes 370.0 370.0 1 PMID:25852984 -4.2.1.10 * escherichia coli 163.0 57.34 3 PMID:13198937;PMID:25852984;PMID:2950851 -4.2.1.10 * eshraghiella crossota 68.99 68.99 1 PMID:25852984 -4.2.1.10 * geobacillus sp. y4.1mc1 15.9 15.9 1 PMID:25852984 -4.2.1.10 * gluconobacter oxydans 84.95 0.2 11 PMID:18540103;PMID:25852984 -4.2.1.10 * halanaerobium hydrogeniformans 131.08 131.08 1 PMID:25852984 -4.2.1.10 * helicobacter pylori 2.92 2.92 1 PMID:8912695 -4.2.1.10 * klebsiella aerogenes 187.7 187.7 1 PMID:25852984 -4.2.1.10 * klebsiella pneumoniae 192.1 192.1 1 PMID:25852984 -4.2.1.10 * lancefieldella rimae 15.64 15.64 1 PMID:25852984 -4.2.1.10 * micromonospora lupini 86.5 86.5 1 PMID:25852984 -4.2.1.10 * mycobacterium tuberculosis 46.37 43.3 3 PMID:1329726;PMID:25852984 -4.2.1.10 * natranaerobius thermophilus 5.16 5.16 1 PMID:25852984 -4.2.1.10 * neurospora crassa 0.096 0.096 1 PMID:4263953 -4.2.1.10 * pseudomonas putida 105.18 105.18 1 PMID:25852984 -4.2.1.10 * psychrobacter sp. prwf-1 75.06 75.06 1 PMID:25852984 -4.2.1.10 * psychromonas ingrahamii 9.39 9.39 1 PMID:25852984 -4.2.1.10 * ruminococcus champanellensis 116.07 116.07 1 PMID:25852984 -4.2.1.10 * salmonella enterica subsp. enterica serovar typhi 229.0 229.0 1 PMID:8216229 -4.2.1.10 * streptomyces acidiscabies 501.9 501.9 1 PMID:25852984 -4.2.1.10 * streptomyces coelicolor 1710.0 946.6 2 PMID:2306211 -4.2.1.10 * thermodesulfobium narugense 17.66 17.66 1 PMID:25852984 -4.2.1.10 * thermomonospora curvata 30.19 30.19 1 PMID:25852984 -4.2.1.10 * xylella fastidiosa 15.06 15.06 1 PMID:25852984 -4.2.1.100 * desulfococcus multivorans 2.0 2.0 1 PMID:17122342 -4.2.1.100 * ferroglobus placidus 31.7 31.7 1 PMID:25630364 -4.2.1.100 * geobacter metallireducens 730.0 550.0 3 PMID:17122342 -4.2.1.100 * syntrophus aciditrophicus 350.0 175.9 2 PMID:17122342 -4.2.1.100 * thauera aromatica 110.0 110.0 3 PMID:10766750;PMID:29312255 -4.2.1.103 * arthrobacter pascens 0.935 0.935 1 PMID:20826798 -4.2.1.103 * pseudomonas putida 17.3 17.3 1 PMID:12244065 -4.2.1.104 * arabidopsis thaliana 2.286 2.286 1 PMID:21494323 -4.2.1.104 * oryza sativa 0.633 0.46799999999999997 2 PMID:21494323 -4.2.1.104 * pseudomonas putida 0.75 0.75 1 * -4.2.1.104 * stutzerimonas stutzeri 1.26 1.26 1 * -4.2.1.104 * synechococcus sp. 5.56 0.615 4 PMID:21057026;PMID:9294430 -4.2.1.104 * synechocystis sp. pcc 6803 1666.7 1666.7 1 PMID:28343358 -4.2.1.104 * thiohalophilus thiocyanatoxydans 0.22 0.115 2 PMID:17964868 -4.2.1.105 * pueraria montana var. lobata 3.408 3.408 1 * -4.2.1.107 * rattus norvegicus 48.0 48.0 1 * -4.2.1.108 * halomonas elongata 16.0 0.3 3 PMID:21468713;PMID:9864317 -4.2.1.11 * archaeoglobus fulgidus 0.79 0.79 1 PMID:11702074 -4.2.1.11 * brucella abortus 10050.0 9091.0 3 PMID:21674187 -4.2.1.11 * candida albicans 60.0 47.5 2 PMID:10825670 -4.2.1.11 * candida parapsilosis 60.0 60.0 1 * -4.2.1.11 * chloroflexus aurantiacus 300.0 223.5 2 PMID:26082925 -4.2.1.11 * clavispora lusitaniae 60.0 60.0 1 * -4.2.1.11 * clostridioides difficile 700.0 700.0 1 PMID:2365093 -4.2.1.11 * enterococcus hirae 124.0 124.0 1 PMID:12869539 -4.2.1.11 * escherichia coli 260.0 209.0 2 PMID:11676541;PMID:4942326 -4.2.1.11 * gallus gallus 92.3 82.8 3 PMID:4093440 -4.2.1.11 * hevea brasiliensis 22.0 22.0 1 PMID:11106410 -4.2.1.11 * homo sapiens 75.0 66.8 4 PMID:6810954 -4.2.1.11 * klebsiella pneumoniae 31.2 15.805 2 * -4.2.1.11 * macaca mulatta 86.54 86.54 1 PMID:4622436 -4.2.1.11 * methanococcus maripaludis 0.107 0.107 1 PMID:8288525 -4.2.1.11 * nakaseomyces glabratus 60.0 60.0 1 * -4.2.1.11 * oncorhynchus keta 92.0 92.0 1 PMID:1169674 -4.2.1.11 * oncorhynchus kisutch 83.0 83.0 1 PMID:1169674 -4.2.1.11 * oncorhynchus mykiss 94.0 94.0 1 PMID:1169674 -4.2.1.11 * oryctolagus cuniculus 67.0 59.0 2 PMID:12044909;PMID:8784922 -4.2.1.11 * pagrus major 76.2 76.2 1 * -4.2.1.11 * pichia kudriavzevii 60.0 60.0 1 * -4.2.1.11 * plasmodium falciparum 30.0 30.0 1 PMID:15606772 -4.2.1.11 * pyrococcus furiosus 13.8 13.8 1 PMID:8080274 -4.2.1.11 * rattus norvegicus 120.0 68.0 7 PMID:15041191;PMID:4413246;PMID:7400110 -4.2.1.11 * ricinus communis 252.4 200.0 3 PMID:6486806 -4.2.1.11 * saccharomyces cerevisiae 442.0 288.5 2 PMID:13678299;PMID:6353993 -4.2.1.11 * schistosoma japonicum 35.81 25.84 2 PMID:20512506 -4.2.1.11 * scomber japonicus 61.7 58.900000000000006 2 * -4.2.1.11 * streptococcus pneumoniae 111.0 111.0 1 PMID:15476816 -4.2.1.11 * streptococcus ratti 1118.0 1018.0 2 PMID:2318530 -4.2.1.11 * sus scrofa 91.0 82.2 3 PMID:10071935;PMID:8593189 -4.2.1.11 * taenia pisiformis 30.71 21.0 2 PMID:25623259 -4.2.1.11 * taenia solium 60.72 60.72 1 PMID:29657009 -4.2.1.11 * trypanosoma brucei 85.0 85.0 1 PMID:12869196 -4.2.1.11 * zea mays 10.3 10.3 1 * -4.2.1.110 * polyporus obtusus 9.0 4.51 2 PMID:1423351 -4.2.1.111 * anthracobia melaloma 1870.0 1870.0 1 PMID:15110094 -4.2.1.112 * syntrophotalea acetylenica 69.2 14.2 5 PMID:10447686;PMID:16511024;PMID:21193613;PMID:7592321 -4.2.1.115 * campylobacter jejuni 0.23 0.11501850000000001 2 PMID:18845311 -4.2.1.116 * metallosphaera sedula 151.0 3.1 3 PMID:19429610 -4.2.1.117 * shewanella oneidensis 7.8 5.0 3 PMID:14702315 -4.2.1.118 * neurospora crassa 257.0 257.0 1 PMID:149131 -4.2.1.118 * penicillium parvum 0.91 0.91 1 PMID:35612974 -4.2.1.119 * aeromonas caviae 1594.0 797.43 2 PMID:12902277 -4.2.1.119 * arabidopsis thaliana 30.0 7.95 4 PMID:16982622 -4.2.1.119 * cucumis sativus 259.0 259.0 1 PMID:1879422 -4.2.1.119 * homo sapiens 0.54 0.22499999999999998 8 PMID:10671535 -4.2.1.119 * rattus norvegicus 48.0 35.45 4 PMID:21263204;PMID:8408009 -4.2.1.120 * clostridium aminobutyricum 12.5 4.5 3 PMID:25452282;PMID:8344309 -4.2.1.120 * clostridium kluyveri 7.38 7.38 1 PMID:8161284 -4.2.1.120 * ignicoccus hospitalis 0.1 0.1 1 PMID:18511565 -4.2.1.120 * metallosphaera sedula 0.04 0.04 1 PMID:18079405 -4.2.1.123 * tetrahymena thermophila 31280.0 15692.5 2 PMID:1892870 -4.2.1.127 * castellaniella defragrans 0.55 0.27543500000000004 2 PMID:20663876;PMID:29156448 -4.2.1.130 * arabidopsis thaliana 0.31 0.013999999999999999 6 PMID:23651081 -4.2.1.130 * escherichia coli 37.0 0.254 4 PMID:21696459;PMID:7848303 -4.2.1.139 * medicago sativa 2020.0 2020.0 1 PMID:8071365 -4.2.1.140 * picrophilus oshimae 5.1 5.1 1 PMID:20023024 -4.2.1.142 * aspergillus parasiticus 0.0836 0.0836 1 PMID:14602595 -4.2.1.143 * aspergillus parasiticus 2750.0 2325.0 2 PMID:8784203;PMID:8995367 -4.2.1.144 * amycolatopsis mediterranei 195.0 133.5 2 PMID:9497318 -4.2.1.147 * methylorubrum extorquens 20.2 20.2 1 PMID:11073907 -4.2.1.148 * cereibacter sphaeroides 1400.0 1400.0 1 PMID:18065535 -4.2.1.148 * chloroflexus aurantiacus 1300.0 1300.0 1 PMID:18065535 -4.2.1.148 * haloarcula hispanica 157.0 157.0 2 PMID:28932214 -4.2.1.149 * escherichia coli 699.9 380.09999999999997 2 PMID:11551212 -4.2.1.149 * proteus sp. (in: enterobacteria) 6088.0 450.0 3 PMID:11409545;PMID:15731894 -4.2.1.150 * clostridium acetobutylicum 6155.0 6155.0 1 PMID:5057466 -4.2.1.150 * metallosphaera sedula 3.0 3.0 1 PMID:21169482 -4.2.1.154 * streptomyces glaucescens 0.309 0.1547855 2 PMID:8218177 -4.2.1.167 * [clostridium] symbiosum 54.0 43.0 2 PMID:10491198;PMID:21434666 -4.2.1.167 * acidaminococcus fermentans 0.0558 0.0558 1 PMID:3691501 -4.2.1.17 * clostridium acetobutylicum 6155.0 6155.0 1 PMID:5057466 -4.2.1.17 * cupriavidus necator 98.0 98.0 1 PMID:25401070 -4.2.1.17 * escherichia coli 973.0 650.0 3 PMID:11969208 -4.2.1.17 * mycobacterium tuberculosis 18.2 13.399999999999999 2 PMID:32649175 -4.2.1.17 * rattus norvegicus 64.0 64.0 1 PMID:10074351 -4.2.1.17 * sus scrofa 1334.0 1334.0 1 PMID:833142 -4.2.1.171 * agrobacterium tumefaciens 18.2 18.2 1 PMID:28559297 -4.2.1.171 * azospirillum brasilense 2.29 2.29 1 PMID:28559297 -4.2.1.171 * micromonospora viridifaciens 41.3 10.27 4 PMID:28559297 -4.2.1.171 * pseudomonas aeruginosa 41.3 41.3 1 PMID:28559297 -4.2.1.175 * archaeoglobus fulgidus 1030.0 1030.0 1 PMID:24096454 -4.2.1.178 * arthrobacter sp. h65-7 19.2 9.865 2 * -4.2.1.178 * pseudarthrobacter chlorophenolicus 101.25 101.25 1 * -4.2.1.180 * thauera aromatica 27.0 14.2 2 PMID:34601806 -4.2.1.19 * neurospora crassa 0.195 0.195 1 PMID:13475302 -4.2.1.19 * saccharomyces cerevisiae 0.31 0.31 1 PMID:4611478 -4.2.1.19 * triticum aestivum 5.7 5.7 1 PMID:12231975 -4.2.1.2 * arabidopsis thaliana 238.0 238.0 1 PMID:9390175 -4.2.1.2 * ascaris suum 388.0 388.0 1 PMID:14711508 -4.2.1.2 * bacteria 971.0 971.0 1 PMID:8593099 -4.2.1.2 * corynebacterium glutamicum 315.0 315.0 1 PMID:16717409 -4.2.1.2 * escherichia coli 2800.0 730.0 3 PMID:1329945;PMID:1917897 -4.2.1.2 * euglena gracilis 1047.0 1047.0 1 PMID:3932328 -4.2.1.2 * helianthus annuus 5.97 5.699999999999999 2 PMID:29920456 -4.2.1.2 * pelotomaculum thermopropionicum 45.0 45.0 1 PMID:17319878 -4.2.1.2 * rattus norvegicus 730.0 725.5 2 PMID:7287666 -4.2.1.2 * rhizopus arrhizus 14.21 9.665 4 PMID:29409732 -4.2.1.2 * saccharolobus solfataricus 205.0 205.0 1 PMID:2124611 -4.2.1.2 * saccharomyces cerevisiae 1150.0 1150.0 1 PMID:1633200 -4.2.1.2 * sus scrofa 450.0 311.5 2 PMID:3771571;PMID:3967032 -4.2.1.2 * thermus thermophilus 1300.0 842.5 2 PMID:25561060;PMID:9647666 -4.2.1.2 * uncultured marine microorganism 726.0 726.0 1 PMID:21092234 -4.2.1.20 * bacillus subtilis 2.8 2.8 1 PMID:4633670 -4.2.1.20 * escherichia coli 1524.0 125.0 5 PMID:1107044;PMID:11209753;PMID:3298982;PMID:816654 -4.2.1.20 * lathyrus oleraceus 10.53 10.53 1 PMID:4666111 -4.2.1.20 * saccharomyces cerevisiae 1.69 1.69 1 PMID:6342605 -4.2.1.20 * salmonella enterica subsp. enterica serovar typhimurium 1605.0 1310.0 9 PMID:10769125;PMID:10801803;PMID:11209753;PMID:12686126;PMID:3298982 -4.2.1.20 * serratia marcescens 8.05 8.05 1 PMID:77857 -4.2.1.20 * thermococcus kodakarensis 119.0 110.0 3 PMID:11029579 -4.2.1.22 * homo sapiens 105.2 4.1 16 PMID:12269827;PMID:18060852;PMID:18776696;PMID:19010420;PMID:19232736;PMID:19733148;PMID:21262193;PMID:681363;PMID:6838228;PMID:7827502;PMID:9737978 -4.2.1.22 * panagrellus redivivus 32.0 32.0 1 PMID:8697099 -4.2.1.22 * rattus norvegicus 1.2 1.2 1 * -4.2.1.22 * saccharomyces cerevisiae 73.0 73.0 1 PMID:10956046 -4.2.1.24 * bos taurus 0.63 0.63 1 PMID:3702740 -4.2.1.24 * coturnix japonica 10.3 8.64 2 PMID:5082517 -4.2.1.24 * drosophila melanogaster 0.283 0.283 1 PMID:12794073 -4.2.1.24 * escherichia coli 0.55 0.55 1 PMID:8439296 -4.2.1.24 * homo sapiens 0.67 0.4 3 PMID:18271513;PMID:20442414;PMID:4052040;PMID:457661 -4.2.1.24 * lathyrus oleraceus 4.33 4.33 1 PMID:9033406 -4.2.1.24 * methanosarcina barkeri 0.39 0.39 1 * -4.2.1.24 * pseudomonas aeruginosa 1.0 1.0 1 PMID:10529243 -4.2.1.24 * rattus sp. 0.29 0.28 3 PMID:19095280 -4.2.1.24 * rhodobacter capsulatus 1.62 1.62 1 PMID:4542319 -4.2.1.24 * saccharomyces cerevisiae 0.27 0.27 1 PMID:2204246 -4.2.1.24 * toxoplasma gondii 0.4 0.4 1 PMID:20442414;PMID:4052040 -4.2.1.25 * azospirillum brasilense 2.07 1.0434999999999999 2 PMID:16950779;PMID:6798025 -4.2.1.27 * pseudomonas sp. 38.0 38.0 1 PMID:13654296 -4.2.1.28 * klebsiella pneumoniae 106.0 93.25 4 PMID:375836;PMID:6756401;PMID:7025894;PMID:9344474 -4.2.1.28 * propionibacterium freudenreichii 197.0 197.0 1 * -4.2.1.28 * salmonella enterica subsp. enterica serovar typhimurium 12.0 11.0 3 PMID:17525464 -4.2.1.28 * secundilactobacillus collinoides 0.77 0.495 2 PMID:12423373 -4.2.1.28 * terrisporobacter glycolicus 1.5 1.5 1 PMID:2936306 -4.2.1.3 * bos taurus 21.4 21.4 1 PMID:1334546 -4.2.1.3 * corynebacterium glutamicum 0.433 0.266 3 PMID:20647021 -4.2.1.3 * cucurbita sp. 2.214 2.17 2 * -4.2.1.3 * escherichia coli 1.9 1.9 1 PMID:12473114 -4.2.1.3 * mycobacterium tuberculosis 118.0 118.0 1 PMID:17384188 -4.2.1.3 * rattus norvegicus 3.4 0.5890000000000001 4 PMID:18294133;PMID:4736701 -4.2.1.3 * rattus rattus 11.1 8.615 2 PMID:12139479 -4.2.1.3 * sulfolobus acidocaldarius 55.0 55.0 1 PMID:11248696 -4.2.1.3 * yarrowia lipolytica 100.0 100.0 1 * -4.2.1.3 * zea mays 4.06 2.00195 4 PMID:25933369;PMID:31751915 -4.2.1.30 * citrobacter freundii 91.9 91.9 3 PMID:22821086 -4.2.1.30 * klebsiella pneumoniae 228.0 65.4 7 PMID:12230560;PMID:17373646;PMID:17615996;PMID:237191;PMID:8798396 -4.2.1.30 * limosilactobacillus reuteri 4.0 4.0 1 PMID:16348166 -4.2.1.31 * arthrobacter sp. 6.55 6.55 1 * -4.2.1.31 * ectopseudomonas oleovorans 108.0 108.0 1 PMID:16349034 -4.2.1.31 * oryctolagus cuniculus 317.0 317.0 1 PMID:2990924 -4.2.1.32 * pseudomonas putida 78.0 78.0 1 * -4.2.1.33 * neurospora crassa 54000.0 27003.1 2 PMID:14087357;PMID:146703 -4.2.1.33 * neurospora sp. 12.3 12.3 1 * -4.2.1.33 * saccharomyces cerevisiae 6.18 6.18 1 PMID:3071717 -4.2.1.34 * aerobic bacterium 7.1 7.1 1 PMID:893377 -4.2.1.34 * clostridium tetanomorphum 24.0 24.0 1 PMID:5903732 -4.2.1.39 * achromobacter xylosoxidans 0.13 0.0335 18 * -4.2.1.39 * alcaligenes sp. 10.2 10.2 1 PMID:1134357 -4.2.1.39 * clostridium aceticum 10.0 5.25 2 PMID:5383859 -4.2.1.39 * clostridium beijerinckii 0.001 0.001 1 PMID:5113600 -4.2.1.39 * clostridium butyricum 0.041 0.041 1 PMID:5113600 -4.2.1.39 * clostridium felsineum 0.08 0.08 1 PMID:5113600 -4.2.1.39 * clostridium pasteurianum 132.0 66.0415 2 PMID:4772682;PMID:5113600;PMID:7154958 -4.2.1.39 * clostridium tetanomorphum 0.01 0.01 1 PMID:5113600 -4.2.1.39 * haloferax volcanii 30.0 30.0 1 PMID:27297879 -4.2.1.39 * halophilic archaeon 0.023 0.023 1 PMID:4153875 -4.2.1.39 * penicillium chrysogenum 1420.0 951.5 2 PMID:4091540 -4.2.1.39 * saccharolobus solfataricus 26.04 26.04 1 PMID:15509194 -4.2.1.39 * thermoplasma acidophilum 2000.0 2000.0 1 * -4.2.1.40 * delftia acidovorans 2.87 2.87 1 PMID:4311826 -4.2.1.40 * escherichia coli 20.1 20.1 1 * -4.2.1.40 * pseudomonas sp. 3.7 3.7 1 PMID:5043319 -4.2.1.41 * agrobacterium fabrum 15.1 15.1 1 PMID:24419616 -4.2.1.41 * delftia acidovorans 5.9 5.9 1 PMID:237186;PMID:4982840 -4.2.1.42 * escherichia coli 0.5 0.5 1 * -4.2.1.43 * azospirillum brasilense 19.8 19.8 1 PMID:16950779 -4.2.1.43 * roseateles saccharophilus 54.0 54.0 1 PMID:237190;PMID:5954356 -4.2.1.44 * klebsiella aerogenes 270.0 270.0 1 PMID:5905122 -4.2.1.45 * salmonella enterica subsp. enterica serovar typhimurium 6.4 6.4 1 PMID:4380946 -4.2.1.45 * yersinia pseudotuberculosis 3.18 1.8125 2 PMID:4288651 -4.2.1.46 * escherichia coli 12.3 3.2 6 PMID:14284740;PMID:4307450;PMID:4309149;PMID:9011374 -4.2.1.46 * saccharopolyspora erythraea 0.4 0.4 1 PMID:3170573 -4.2.1.46 * salmonella enterica subsp. enterica serovar typhimurium 930.0 467.2 2 PMID:1993076;PMID:9557873 -4.2.1.46 * streptomyces peucetius 0.2 0.2 1 PMID:1588310 -4.2.1.46 * streptomyces rimosus 0.04 0.04 1 PMID:4346066 -4.2.1.46 * streptomyces sp. c5 0.31 0.31 1 PMID:1588310 -4.2.1.47 * chlorovirus heliozoae 0.63 0.63 1 PMID:17974560 -4.2.1.47 * escherichia coli 8.4 2.3 3 PMID:14299611;PMID:9257704;PMID:9525924 -4.2.1.47 * homo sapiens 0.7 0.40499999999999997 2 PMID:9525924;PMID:9662431 -4.2.1.47 * klebsiella pneumoniae 7.09 7.09 1 PMID:7679567 -4.2.1.47 * paramecium bursaria chlorella virus-1 0.48 0.48 1 PMID:17974560 -4.2.1.47 * sus scrofa 0.036 0.036 1 PMID:4076184 -4.2.1.48 * mus musculus 580.0 580.0 1 PMID:5573236 -4.2.1.49 * bacillus subtilis 0.278 0.278 1 PMID:4990470 -4.2.1.49 * bos taurus 1.6 0.8655 2 PMID:33176 -4.2.1.49 * comamonas testosteroni 0.248 0.248 1 PMID:25660 -4.2.1.49 * pseudomonas putida 2.18 2.12 5 PMID:18470;PMID:235308;PMID:33176;PMID:5412708 -4.2.1.50 * citrullus lanatus 0.355 0.355 1 * -4.2.1.51 * acinetobacter calcoaceticus 84.2 84.2 1 PMID:3046943 -4.2.1.51 * amycolatopsis methanolica 33.3 33.3 1 PMID:7755580 -4.2.1.51 * bacillus subtilis 17.5 13.85 2 PMID:104661;PMID:3110557 -4.2.1.51 * corynebacterium glutamicum 9.48 8.47 2 PMID:14749915;PMID:1780276 -4.2.1.51 * cupriavidus necator 24.9 24.9 1 PMID:1262315 -4.2.1.51 * escherichia coli 18600.0 103.3 8 PMID:10769128;PMID:20137911;PMID:3037264;PMID:4557843;PMID:795664 -4.2.1.51 * pantoea agglomerans 29.4 29.4 1 PMID:1897969 -4.2.1.51 * saccharomyces cerevisiae 72.39 64.62 2 * -4.2.1.53 * elizabethkingia meningoseptica 0.39 0.17 5 PMID:19465645 -4.2.1.53 * lysinibacillus fusiformis 1580.0 135.0 6 PMID:22189865 -4.2.1.53 * macrococcoides caseolyticum 3.3 3.3 1 PMID:22203098 -4.2.1.53 * paracoccus aminophilus 5.21 5.21 1 PMID:34112373 -4.2.1.53 * rhodococcus erythropolis 1.266 0.615 5 * -4.2.1.53 * staphylococcus aureus 7547.0 7547.0 1 PMID:33376139 -4.2.1.53 * stenotrophomonas maltophilia 3.69 0.7250000000000001 6 PMID:22261174 -4.2.1.54 * anaerotignum propionicum 0.031 0.031 1 PMID:22810300 -4.2.1.54 * megasphaera elsdenii 6.9 6.9 1 * -4.2.1.55 * ferroglobus placidus 5.7 5.7 1 PMID:25630364 -4.2.1.57 * pseudomonas citronellolis 25.8 25.8 1 * -4.2.1.59 * escherichia coli 0.089 0.089 1 PMID:4881058 -4.2.1.6 * klebsiella pneumoniae 7.82 7.82 1 PMID:6759856 -4.2.1.6 * mycobacterium butyricum 4.56 4.56 1 PMID:7295736 -4.2.1.6 * pseudomonas sp. 38.0 38.0 1 PMID:422572;PMID:7154959 -4.2.1.62 * saccharomyces cerevisiae 0.121 0.121 1 PMID:5442273 -4.2.1.65 * lupinus angustifolius 0.371 0.371 1 PMID:4627358 -4.2.1.65 * pseudomonas sp. 54.7 54.7 1 * -4.2.1.65 * sorghum bicolor 0.371 0.371 1 PMID:4627358 -4.2.1.66 * fusarium lateritium 1109.0 1109.0 1 PMID:8409923 -4.2.1.66 * microdochium sorghi 555.0 555.0 1 PMID:1416986 -4.2.1.67 * pseudomonas sp. 2.33 2.33 1 PMID:237189 -4.2.1.68 * aureobasidium pullulans 29.1 29.1 1 * -4.2.1.68 * sus scrofa 0.066 0.066 1 PMID:5050937 -4.2.1.69 * albifimbria verrucaria 73.65 73.65 1 * -4.2.1.70 * tetrahymena pyriformis 13.2 13.2 1 PMID:14165924 -4.2.1.75 * bacillus subtilis 9.4 9.4 1 PMID:7628476 -4.2.1.75 * escherichia coli 25.0 25.0 1 PMID:2557837 -4.2.1.75 * homo sapiens 54.7 44.035 2 PMID:15496592;PMID:21570665 -4.2.1.75 * rattus norvegicus 9.7 9.7 1 PMID:17763925 -4.2.1.75 * synechococcus elongatus pcc 7942 = fachb-805 40.0 40.0 1 PMID:12163155 -4.2.1.76 * acanthamoeba polyphaga mimivirus 0.0042 0.0042 1 PMID:20538863 -4.2.1.76 * chlorovirus heliozoae 0.023 0.023 1 PMID:20538863 -4.2.1.77 * azospirillum brasilense 26.1 26.1 2 PMID:25678137;PMID:28559297 -4.2.1.77 * colwellia psychrerythraea 25.4 25.4 2 PMID:25678137;PMID:28559297 -4.2.1.77 * homo sapiens 7.37 7.37 1 PMID:25678137 -4.2.1.77 * micromonospora viridifaciens 17.6 17.6 1 PMID:28559297 -4.2.1.79 * escherichia coli 0.8 0.4025 2 PMID:11782506 -4.2.1.79 * salmonella enterica 2.8 2.6 3 PMID:11294638 -4.2.1.79 * yarrowia lipolytica 1.08 1.08 1 * -4.2.1.8 * escherichia coli 203.1 203.1 1 PMID:3038546 -4.2.1.80 * escherichia coli 538.0 538.0 1 PMID:9492273 -4.2.1.80 * pseudomonas putida 45.0 4.6 4 PMID:7287632 -4.2.1.81 * cereibacter sphaeroides 7.2 7.2 1 PMID:6978882 -4.2.1.81 * pseudomonas sp. 13.6 8.35 2 PMID:7107563 -4.2.1.82 * haloferax volcanii 1.1 1.1 1 PMID:19584053 -4.2.1.82 * pseudomonas sp. 1.38 1.38 1 PMID:7154961 -4.2.1.83 * phytopseudomonas straminea 113.0 110.5 2 PMID:17284837;PMID:3985968 -4.2.1.83 * sphingomonas paucimobilis 557.0 557.0 1 PMID:11092855 -4.2.1.84 * agrobacterium tumefaciens 13.7 13.7 1 PMID:11607511 -4.2.1.84 * aplysina cavernicola 16.2 16.2 1 PMID:23966036 -4.2.1.84 * arthrobacter sp. 9.17 9.17 1 * -4.2.1.84 * brevibacterium sp. 2000.0 1745.0 4 PMID:1527703;PMID:3768004;PMID:8797859 -4.2.1.84 * caldalkalibacillus thermarum 383.8 225.9 3 PMID:34454178 -4.2.1.84 * comamonas testosteroni 110.0 15.0 9 PMID:12729727;PMID:17267045 -4.2.1.84 * corynebacterium pseudodiphtheriticum 315.2 315.2 1 * -4.2.1.84 * klebsiella oxytoca 45.2 45.2 1 * -4.2.1.84 * mesorhizobium loti 168.0 6.105 6 PMID:11607511 -4.2.1.84 * mesorhizobium sp. 686.0 439.0 2 * -4.2.1.84 * microbacterium imperiale 11.04 11.04 1 * -4.2.1.84 * mutarda arvensis 66.6 66.6 1 PMID:17916498 -4.2.1.84 * nocardia sp. 195.1 130.95 6 * -4.2.1.84 * prescottella equi 6290.0 3567.0 2 PMID:19662400 -4.2.1.84 * pseudomonas chlororaphis 1840.0 931.6 2 PMID:18408036;PMID:3830164 -4.2.1.84 * pseudomonas putida 1590.0 434.0 14 PMID:24698299;PMID:24944015;PMID:9154927 -4.2.1.84 * pseudonocardia thermophila 2463.0 121.35 10 PMID:35919716 -4.2.1.84 * rhizobium leguminosarum 1.12 0.28500000000000003 4 PMID:11607511 -4.2.1.84 * rhodococcus erythropolis 860.0 860.0 1 * -4.2.1.84 * rhodococcus rhodochrous 579.0 140.915 10 PMID:2013281;PMID:20886813;PMID:23100776;PMID:28644864;PMID:3421954 -4.2.1.84 * rhodococcus sp. (in: high g+c gram-positive bacteria) 1358.0 27.99 19 PMID:10101282;PMID:17330219;PMID:17635193;PMID:2920826 -4.2.1.84 * sinapis alba 11.8 11.8 1 PMID:17916498 -4.2.1.84 * sinorhizobium meliloti 0.22 0.22 1 PMID:11607511 -4.2.1.85 * eubacterium barkeri 0.14 0.14 1 PMID:6489933 -4.2.1.88 * arthrobacter synephrinum 1.8 1.8 1 PMID:3729420 -4.2.1.9 * aspergillus fumigatus 18.0 18.0 1 PMID:23028460 -4.2.1.9 * cupriavidus necator 3.4 3.4 1 PMID:25081555 -4.2.1.9 * escherichia coli 63.0 31.708 2 PMID:13727223;PMID:8325851 -4.2.1.9 * methanococcus aeolicus 1.63 1.63 1 PMID:2002010 -4.2.1.9 * mycobacterium tuberculosis 0.024 0.024 1 PMID:20864475 -4.2.1.9 * neurospora crassa 10.13 6.140000000000001 2 PMID:4986563 -4.2.1.9 * saccharolobus solfataricus 10.7 5.366549999999999 2 PMID:26102631;PMID:35546366 -4.2.1.9 * spinacia oleracea 0.18 0.156 2 PMID:7648198 -4.2.1.90 * aureobasidium pullulans 0.17 0.17 1 * -4.2.1.90 * scheffersomyces stipitis 0.0083 0.0083 1 * -4.2.1.90 * schwanniomyces polymorphus 0.0085 0.0085 1 * -4.2.1.91 * brevundimonas diminuta 0.0063 0.00375 2 PMID:3600377;PMID:3924095 -4.2.1.91 * nicotiana sylvestris 0.0006 0.0006 1 * -4.2.1.91 * pantoea agglomerans 29.4 26.54 2 PMID:1897969 -4.2.1.91 * pseudomonas aeruginosa 307.7 51.479 4 PMID:1733946 -4.2.1.91 * sorghum bicolor 0.00425 0.00425 1 PMID:3124763 -4.2.1.92 * camellia sinensis 0.2 0.2 1 PMID:26886573 -4.2.1.92 * capsicum annuum 5.44 3.88 2 PMID:23076732 -4.2.1.94 * bipolaris oryzae 36.6 36.6 1 * -4.2.1.94 * pyricularia grisea 28.0 28.0 1 PMID:9571787 -4.2.1.96 * homo sapiens 5.2 5.2 1 PMID:8444860 -4.2.1.96 * rattus norvegicus 0.0134 0.0089 2 PMID:12683953 -4.2.1.98 * eubacterium sp. 0.7094 0.7047 2 PMID:4052439 -4.2.1.99 * yarrowia lipolytica 1.33 1.33 1 * -4.2.2.1 * arthrobacter globiformis 297.2 297.2 1 PMID:27878509 -4.2.2.1 * cutibacterium acnes 7.75 7.75 1 PMID:43356 -4.2.2.1 * neobacillus niacini 136.7 136.7 1 PMID:25680511 -4.2.2.1 * streptococcus agalactiae 400000.0 3680.0 3 PMID:10739920;PMID:18771010 -4.2.2.1 * streptococcus pneumoniae 231.4 231.4 1 PMID:12446724 -4.2.2.1 * streptococcus pyogenes phage h4489a 9.62 9.54 2 * -4.2.2.10 * aspergillus flavus 18.33 9.322999999999999 2 * -4.2.2.10 * aspergillus niger 32.0 17.875 4 PMID:12000753;PMID:25382689 -4.2.2.10 * bacillus pumilus 175.0 175.0 1 * -4.2.2.10 * bacillus sp. (in: firmicutes) 1433.0 1433.0 1 * -4.2.2.10 * fusarium lateritium 3.2 3.2 1 * -4.2.2.10 * neurospora crassa 377.0 377.0 1 * -4.2.2.10 * oidiodendron echinulatum 4.5 4.5 1 PMID:22359214 -4.2.2.10 * penicillium citrinum 12.9 7.2 2 PMID:19747102 -4.2.2.10 * pseudomonas marginalis 1502.0 825.0 2 PMID:12630908 -4.2.2.10 * shouchella clausii 297.0 297.0 1 PMID:22695924 -4.2.2.11 * agrobacterium tumefaciens 1.14 1.14 1 PMID:20507980 -4.2.2.11 * aspergillus oryzae 67.0 67.0 1 * -4.2.2.11 * flammeovirga sp. my04 620.0 442.0 2 PMID:26519393 -4.2.2.11 * flammeovirga sp. nj-04 3343.7 2604.9 3 PMID:28942564 -4.2.2.11 * flavobacterium sp. 265.4 265.4 1 PMID:23111633 -4.2.2.11 * haliotis discus hannai 2490.0 2490.0 1 PMID:20393774 -4.2.2.11 * isoptericola halotolerans 8643.0 8409.0 5 PMID:24053829;PMID:30065151 -4.2.2.11 * klebsiella pneumoniae 765.0 765.0 1 PMID:20826807 -4.2.2.11 * lambis sp. aab-2014 1.54 1.54 1 * -4.2.2.11 * pseudoalteromonas sp. 4803.0 4803.0 1 PMID:21339950 -4.2.2.11 * pseudomonas fluorescens 653.0 390.0 5 PMID:21170604 -4.2.2.11 * saccharophagus degradans 46.0 41.4 3 PMID:22391735 -4.2.2.11 * vibrio sp. 2152.0 2152.0 3 PMID:19941025;PMID:23299986 -4.2.2.11 * vibrio sp. nj-04 3359.0 2416.0 3 PMID:29698759 -4.2.2.11 * vibrio sp. w13 457.0 16.725 4 PMID:25661880;PMID:29428387 -4.2.2.11 * wenyingzhuangia fucanilytica 27.03 23.34 3 PMID:302448453 -4.2.2.12 * bacillus sp. (in: firmicutes) 6.28 6.28 1 PMID:9758797 -4.2.2.12 * microbacterium sp. 28.2 28.2 1 PMID:25054177 -4.2.2.12 * paenibacillus alginolyticus 2.62 2.62 1 PMID:10347025 -4.2.2.13 * gracilariopsis lemaneiformis 93.3 93.3 1 PMID:8461323 -4.2.2.14 * trichoderma sp. 162.0 162.0 1 PMID:16025327 -4.2.2.16 * microbacterium sp. 145.2 145.2 1 PMID:12074698 -4.2.2.16 * paenarthrobacter ureafaciens 2269.0 2269.0 1 PMID:10899545 -4.2.2.16 * pseudarthrobacter oxydans 1432.0 1432.0 1 PMID:12696949 -4.2.2.17 * nocardioidaceae bacterium broad-1 147.0 147.0 1 * -4.2.2.17 * nocardioides luteus 114.0 114.0 1 * -4.2.2.17 * nocardioides sp. 131.0 131.0 1 * -4.2.2.17 * paenarthrobacter ureafaciens 172.0 149.5 2 PMID:12889813 -4.2.2.17 * streptomyces peucetius subsp. caesius 420.84 420.84 1 PMID:32423668 -4.2.2.18 * arthrobacter globiformis 294.0 187.75 2 PMID:7764697 -4.2.2.18 * arthrobacter sp. 933.0 672.0 4 PMID:7764697 -4.2.2.18 * arthrobacter sp. 161mfsha2.1 2391.0 2391.0 1 PMID:25794105 -4.2.2.18 * aspergillus foetidus 100.9 100.9 1 PMID:24031675 -4.2.2.18 * bacillus sp. (in: firmicutes) 45.8 45.8 1 * -4.2.2.18 * leifsonia sp. t88-4 644.0 644.0 1 * -4.2.2.18 * microbacterium sp. s48-1 106.0 106.0 1 * -4.2.2.18 * paenarthrobacter aurescens 381.0 198.7 2 PMID:20933390;PMID:23648026 -4.2.2.18 * paenarthrobacter ilicis 853.0 853.0 1 * -4.2.2.18 * paenarthrobacter ureafaciens 290.0 290.0 1 * -4.2.2.18 * pseudarthrobacter chlorophenolicus 902.0 902.0 1 * -4.2.2.18 * streptomyces sp. 256.0 256.0 1 PMID:7764697 -4.2.2.18 * thermothielavioides terrestris 254.9 254.9 1 PMID:24031675 -4.2.2.19 * pedobacter heparinus 80.8 80.8 1 PMID:11500043 -4.2.2.2 * actinomadura keratinilytica 21889.0 21889.0 1 * -4.2.2.2 * bacillus licheniformis 320.0 211.0 5 * -4.2.2.2 * bacillus pumilus 2893.0 1511.95 2 PMID:20596756;PMID:25287558 -4.2.2.2 * bacillus sp. (in: firmicutes) 1000.0 106.0 4 PMID:10759850;PMID:19202269;PMID:20467237 -4.2.2.2 * bacillus sp. n16-5 1870.0 1870.0 1 PMID:26070675 -4.2.2.2 * bacillus subtilis 3194.0 1286.0 6 PMID:21915717;PMID:23510095;PMID:25497420;PMID:28975516 -4.2.2.2 * bacteroides thetaiotaomicron 50.0 50.0 1 PMID:3968032 -4.2.2.2 * caldicellulosiruptor kronotskyensis 172.8 172.8 1 * -4.2.2.2 * colletotrichum gloeosporioides 248.0 248.0 1 PMID:8012046 -4.2.2.2 * fusarium solani 202.0 202.0 1 PMID:3310898 -4.2.2.2 * georgenia muralis 124.0 124.0 1 PMID:25209746 -4.2.2.2 * paenibacillus campinasensis 1623.0 1623.0 1 * -4.2.2.2 * paenibacillus polymyxa 298.5 289.0 3 PMID:30373112;PMID:31234557 -4.2.2.2 * paenibacillus sp. 2060.0 2060.0 1 PMID:24612647 -4.2.2.2 * paenibacillus sp. 0602 1602.0 1602.0 1 PMID:28028551 -4.2.2.2 * penicillium occitanis (nom. inval.) 194.3 194.3 1 * -4.2.2.2 * phytophthora capsici 860.0 805.0 2 PMID:21470403 -4.2.2.2 * priestia megaterium 852.0 852.0 1 PMID:22541951 -4.2.2.2 * streptomyces coelicolor 0.22 0.18 2 PMID:18317750 -4.2.2.2 * streptomyces fradiae 176.0 176.0 1 * -4.2.2.2 * streptomyces nitrosporeus 319.0 319.0 1 * -4.2.2.2 * streptomyces thermocarboxydus 177.0 90.015 2 PMID:20139595 -4.2.2.2 * uncultured bacterium 2096.0 1326.1 4 * -4.2.2.2 * volvariella volvacea 30.07 30.07 1 PMID:25341402 -4.2.2.2 * xanthomonas campestris 0.66 0.49 2 PMID:18317750 -4.2.2.20 * proteus vulgaris 3180.0 180.0 4 PMID:25077839;PMID:32573715;PMID:9083041 -4.2.2.21 * pedobacter heparinus 43.0 22.225 2 PMID:3814619;PMID:5647268 -4.2.2.21 * proteus vulgaris 290.6 45.85 10 PMID:15691229;PMID:32573715;PMID:5647268;PMID:9083041 -4.2.2.21 * vibrio hyugaensis 17.54 10.6 2 PMID:34356824 -4.2.2.21 * vibrio sp. fc509 1480.0 1220.0 6 PMID:28963345 -4.2.2.22 * aspergillus nidulans 63.7 31.84 4 * -4.2.2.23 * acetivibrio thermocellus 4.5 4.5 1 PMID:26921189 -4.2.2.23 * fragaria chiloensis 312810.0 171645.0 2 PMID:31805495 -4.2.2.23 * penicillium chrysogenum 2.0 2.0 1 PMID:25666014 -4.2.2.25 * bacillus sp. (in: firmicutes) 9.34 9.34 1 PMID:9056228 -4.2.2.25 * geobacillus stearothermophilus 0.99 0.99 1 PMID:16482399 -4.2.2.25 * unidentified microorganism 0.671 0.671 1 PMID:8919816 -4.2.2.26 * cellulophaga sp. sy116 76.8 33.7 6 PMID:29362921 -4.2.2.26 * shewanella sp. 32.0 24.0 3 PMID:25335746 -4.2.2.29 * pseudomonas aeruginosa 0.013 0.013 1 PMID:16475802 -4.2.2.3 * agarivorans sp. 108.5 54.321 2 PMID:19002649 -4.2.2.3 * agrobacterium tumefaciens 1.14 1.14 1 PMID:20507980 -4.2.2.3 * aplysia kurodai 5796.0 2057.0 10 PMID:20708706;PMID:21689718;PMID:28011642 -4.2.2.3 * aspergillus oryzae 67.24 67.12 2 * -4.2.2.3 * azotobacter chroococcum 93.88 93.88 1 PMID:10049370 -4.2.2.3 * chlorella virus 0.021 0.021 1 PMID:10547443 -4.2.2.3 * flammeovirga sp. my04 2025.0 2025.0 1 PMID:29472911 -4.2.2.3 * flammeovirga sp. nj-04 3343.7 2604.9 3 PMID:28942564 -4.2.2.3 * haliotis discus discus 644.6 644.6 1 * -4.2.2.3 * haliotis discus hannai 2490.0 2138.0 2 PMID:16697989;PMID:20393774 -4.2.2.3 * isoptericola halotolerans 8643.0 8197.0 4 PMID:24053829;PMID:30065151 -4.2.2.3 * klebsiella pneumoniae 937.0 937.0 1 PMID:20826807 -4.2.2.3 * nitratiruptor sp. sb155-2 1620.0 1620.0 1 PMID:27231344 -4.2.2.3 * paradendryphiella salina 2.86 2.86 1 PMID:9145523 -4.2.2.3 * pseudoalteromonas sp. 4803.0 4803.0 2 PMID:21339950 -4.2.2.3 * pseudomonas aeruginosa 0.926 0.4767 2 PMID:15136569 -4.2.2.3 * pseudomonas fluorescens 1123.0 390.0 11 PMID:21170604 -4.2.2.3 * pseudomonas sp. e03 222.0 222.0 1 PMID:25257600 -4.2.2.3 * saccharophagus degradans 67.0 41.4 3 PMID:22391735 -4.2.2.3 * sphingomonas sp. 109.0 45.0 5 PMID:10669804;PMID:10833394;PMID:16233753 -4.2.2.3 * thalassomonas sp. ld5 1147.2 678.95 4 PMID:31888109 -4.2.2.3 * vibrio sp. 2152.0 1776.5 2 PMID:19941025;PMID:23299986 -4.2.2.3 * vibrio sp. nj-04 3359.0 2416.0 3 PMID:29698759 -4.2.2.3 * vibrio sp. w13 457.0 16.725 4 PMID:25661880;PMID:29428387 -4.2.2.3 * vibrio splendidus 198.0 119.0 3 PMID:30135412 -4.2.2.3 * wenyingzhuangia fucanilytica 27.03 23.34 3 PMID:302448453 -4.2.2.5 * aeromonas sp. 99.7 99.7 1 PMID:803822 -4.2.2.5 * arthrobacter sp. mat3885 8.5 8.5 1 PMID:25912370 -4.2.2.5 * bacteroides stercoris 57.03 30.39 2 PMID:12071957;PMID:18226546 -4.2.2.5 * paenarthrobacter aurescens 4.0 4.0 1 PMID:28799715 -4.2.2.5 * pedobacter heparinus 541.0 81.25 8 PMID:11327856;PMID:11500043;PMID:8526872 -4.2.2.5 * pseudopedobacter saltans 489.0 214.0 3 * -4.2.2.6 * erwinia aroidea 0.0053 0.0053 1 * -4.2.2.7 * aspergillus flavus 44.6 44.6 2 PMID:19214796 -4.2.2.7 * bacteroides cellulosilyticus 738.3 738.3 1 PMID:33079966 -4.2.2.7 * bacteroides stercoris 109.9 23.619999999999997 4 PMID:10920269;PMID:19566715 -4.2.2.7 * bacteroides thetaiotaomicron 107.8 101.4 3 PMID:19801541 -4.2.2.7 * pedobacter heparinus 7.8 7.8 1 * -4.2.2.8 * bacteroides stercoris 51.81 26.88 4 PMID:19908038 -4.2.2.8 * pedobacter heparinus 149.0 149.0 1 PMID:21445884 -4.2.2.9 * erwinia sp. 4.1 4.1 1 * -4.2.2.9 * lachnospira multipara 1.311 1.311 1 PMID:11472526 -4.2.3.1 * arabidopsis thaliana 3.8 1.90049 2 PMID:8706836;PMID:9748328 -4.2.3.1 * bacillus subtilis 8.8 0.018 3 PMID:4630852 -4.2.3.1 * corynebacterium glutamicum 3.6 3.6 1 PMID:8074505 -4.2.3.1 * escherichia coli 7.7 7.7 1 PMID:6316258 -4.2.3.1 * lathyrus oleraceus 0.012 0.012 1 * -4.2.3.1 * lemna aequinoctialis 0.0261 0.0261 1 PMID:16663833 -4.2.3.1 * methanosarcina acetivorans c2a 1.6 1.6 1 PMID:19761441 -4.2.3.1 * mycobacterium tuberculosis 1.05 1.05 1 PMID:18621388 -4.2.3.1 * neurospora crassa 1.73 1.73 1 PMID:13823379 -4.2.3.104 * zingiber zerumbet 5.08 4.445 4 PMID:32624945 -4.2.3.114 * thymus vulgaris 149.0 149.0 1 PMID:1897973 -4.2.3.12 * drosophila melanogaster 0.0632 0.00891 3 PMID:12123838;PMID:2110003 -4.2.3.12 * escherichia coli 0.09936 0.050245000000000005 2 PMID:12123838 -4.2.3.12 * homo sapiens 57.4 0.0574 13 PMID:10531334;PMID:11744995;PMID:12123838;PMID:1308853;PMID:14654981;PMID:3536512;PMID:8216273;PMID:8304107;PMID:8307017 -4.2.3.12 * rattus norvegicus 0.2883 0.28245 2 PMID:1939130;PMID:8307017 -4.2.3.12 * salmo salar 4.6 4.6 1 PMID:2651122 -4.2.3.12 * synechocystis sp. 0.09767 0.049030000000000004 2 PMID:12123838 -4.2.3.124 * niallia circulans 18.1 9.600000000000001 2 PMID:10344560;PMID:10470681 -4.2.3.13 * gossypium arboreum 0.036 0.03 3 PMID:8554317;PMID:8904844 -4.2.3.13 * gossypium hirsutum 0.433 0.0006230000000000001 6 PMID:10075752;PMID:15849309 -4.2.3.17 * taxus canadensis 0.0003 0.0003 1 PMID:9016812 -4.2.3.19 * cucurbita maxima 0.01 0.01 1 PMID:12228665 -4.2.3.19 * fusarium verticillioides 0.123 0.123 1 PMID:4331199 -4.2.3.19 * marah macrocarpa 0.005 0.005 1 PMID:16659781 -4.2.3.194 * persicaria hydropiper 0.000547 0.0002735965 2 * -4.2.3.2 * oryctolagus cuniculus 0.914 0.914 1 PMID:5498429 -4.2.3.2 * pantoea agglomerans 0.000156 0.000156 1 PMID:4357716 -4.2.3.2 * pantoea ananatis 0.00014 0.00014 1 PMID:4357716 -4.2.3.2 * pectobacterium carotovorum 0.00022 0.00022 1 PMID:4357716 -4.2.3.2 * rattus norvegicus 0.073 0.073 1 PMID:5498429 -4.2.3.23 * cichorium intybus 6.24 6.24 1 PMID:9701594 -4.2.3.24 * artemisia annua 3.53 3e-05 65 PMID:11185551;PMID:16908191 -4.2.3.25 * actinidia arguta 0.039 0.039 1 * -4.2.3.25 * actinidia polygama 0.013 0.013 1 * -4.2.3.25 * clarkia breweri 0.0004 0.0004 1 PMID:7864636 -4.2.3.25 * fragaria x ananassa 6.7e-06 6.7e-06 1 PMID:17209074 -4.2.3.27 * arabidopsis thaliana 0.00014 4.2e-05 5 PMID:17468218 -4.2.3.27 * populus alba 4967.0 0.00012 9 PMID:15848197;PMID:17587373;PMID:17711876 -4.2.3.27 * populus tremula x populus alba 0.012 3.15e-05 4 PMID:11506373;PMID:17122071 -4.2.3.27 * populus tremuloides 0.521 0.521 1 PMID:7768893 -4.2.3.27 * quercus robur 0.333 0.333 1 * -4.2.3.27 * salix discolor 0.011 0.006 2 PMID:9501144 -4.2.3.3 * bacillus subtilis 150.0 150.0 1 PMID:29514981 -4.2.3.3 * proteus vulgaris 9.43 9.43 1 PMID:1386 -4.2.3.3 * roseateles saccharophilus 5.57 5.57 1 PMID:4368914 -4.2.3.3 * thermus sp. gh5 6000.0 6000.0 1 PMID:20419481 -4.2.3.37 * streptomyces coelicolor 18.0 18.0 1 PMID:28967743 -4.2.3.4 * aspergillus nidulans 14.9 12.2 2 PMID:15273308;PMID:8037684 -4.2.3.4 * bacillus subtilis 14.6 14.6 1 PMID:97286 -4.2.3.4 * escherichia coli 44.0 0.0225 20 PMID:17451239;PMID:3037261;PMID:6386050 -4.2.3.4 * lathyrus oleraceus 0.59 0.59 1 * -4.2.3.46 * malus domestica 0.027 0.027 1 PMID:17140613 -4.2.3.5 * bacillus subtilis 0.92 0.92 1 PMID:97285 -4.2.3.5 * escherichia coli 14.8 14.8 1 PMID:2969724 -4.2.3.5 * mycobacterium tuberculosis 0.004 0.004 1 PMID:18445278 -4.2.3.5 * neurospora crassa 32.1 32.1 1 PMID:2969724 -4.2.3.5 * staphylococcus aureus 4.0 4.0 1 PMID:8885411 -4.2.3.6 * escherichia coli 0.222 0.222 1 * -4.2.3.6 * fusarium sporotrichioides 0.222 0.222 1 * -4.2.3.62 * heteroscyphus planus 268.0 268.0 1 * -4.2.3.63 * heteroscyphus planus 268.0 268.0 1 * -4.2.3.64 * heteroscyphus planus 5433.0 5433.0 1 * -4.2.3.66 * citrus x microcarpa 5180.0 5180.0 1 * -4.2.3.7 * streptomyces exfoliatus 0.324 0.324 1 PMID:8180213 -4.2.3.7 * streptomyces sp. 0.287 0.287 1 PMID:3579312 -4.2.3.70 * pogostemon cablin 180.0 180.0 1 PMID:2171435 -4.2.3.72 * solidago canadensis 49.9 49.9 1 PMID:10190971 -4.2.3.8 * ricinus communis 0.359 0.14685 4 PMID:16660566;PMID:3985625;PMID:8954576;PMID:9521827 -4.2.3.82 * santalum album 0.067 0.067 1 PMID:29438678 -4.2.3.82 * santalum spicatum 0.069 0.069 1 PMID:29438678 -4.2.3.9 * aspergillus terreus 0.0236 0.0236 1 PMID:10775423 -4.2.3.9 * penicillium roqueforti 0.07 0.07 1 PMID:2544140 -4.2.99.18 * homo sapiens 0.003133 0.003133 1 PMID:9480425 -4.2.99.18 * mus musculus 19.0 2.34e-05 10 PMID:17166779;PMID:2457585 -4.2.99.18 * rattus norvegicus 0.00155 0.00155 1 PMID:6825667 -4.2.99.21 * pseudomonas aeruginosa 12.89 12.89 1 PMID:11937513 -4.2.99.22 * tulipa gesneriana 4300.0 1455.0 6 PMID:22474185;PMID:23649245;PMID:30284210 -4.2.99.23 * tulipa gesneriana 740.0 236.0 4 PMID:30284210 -4.3.1.1 * bacillus sp. (in: firmicutes) 2500.0 2200.0 3 PMID:10334861 -4.3.1.1 * campylobacter jejuni 191.0 106.7 4 PMID:18433445 -4.3.1.1 * cytophaga sp. 301.0 301.0 1 PMID:12761198 -4.3.1.1 * escherichia coli 800.0 219.0 5 PMID:10334861;PMID:3003513;PMID:4584395;PMID:8047016 -4.3.1.1 * haemophilus influenzae 20.5 20.5 1 PMID:9092705 -4.3.1.1 * hafnia alvei 236.8 236.8 1 * -4.3.1.1 * pseudomonas aeruginosa 38.35 31.21 3 PMID:27988856 -4.3.1.1 * pseudomonas fluorescens 229.0 221.5 2 PMID:10334861;PMID:3003513;PMID:6438071 -4.3.1.1 * yersinia enterocolitica 0.207 0.202 3 PMID:19118360 -4.3.1.1 * yersinia pestis 0.2 0.05 11 PMID:18451035;PMID:19118360 -4.3.1.1 * yersinia pseudotuberculosis 80.0 0.072 9 PMID:18451035;PMID:19118360 -4.3.1.10 * rattus norvegicus 1.48 1.48 1 PMID:5583990 -4.3.1.12 * clostridium sporogenes 6.84 4.98 2 PMID:4373469;PMID:4399881 -4.3.1.13 * rattus norvegicus 0.49 0.49 1 PMID:4761084 -4.3.1.14 * clostridium sp. 0.37 0.37 1 PMID:4420467 -4.3.1.15 * escherichia coli 90.3 45.254999999999995 2 PMID:12821154 -4.3.1.15 * pseudomonas sp. 4.0 4.0 1 PMID:240767 -4.3.1.15 * salmonella enterica 4.9 4.9 1 PMID:27010356 -4.3.1.15 * salmonella enterica subsp. enterica serovar typhimurium 191.0 0.351 5 PMID:12821154;PMID:18025549;PMID:3275662 -4.3.1.16 * pseudomonas sp. 8.0 8.0 1 PMID:10481099 -4.3.1.16 * pseudomonas sp. n99 2.54 2.54 1 PMID:28290777 -4.3.1.16 * pseudomonas sp. t62 39.0 39.0 1 PMID:19193709 -4.3.1.17 * arthrobacter globiformis 660.0 660.0 1 PMID:322657 -4.3.1.17 * campylobacter jejuni 115.0 115.0 1 PMID:14688104 -4.3.1.17 * corynebacterium glyciniphilum 0.262 0.262 1 * -4.3.1.17 * corynebacterium sp. 110.0 110.0 1 * -4.3.1.17 * escherichia coli 307.0 307.0 1 PMID:15498577 -4.3.1.17 * geobacter sulfurreducens 0.041 0.041 1 PMID:18245290 -4.3.1.17 * homo sapiens 137.0 116.5 2 PMID:15618015 -4.3.1.17 * limosilactobacillus fermentum 0.649 0.649 1 * -4.3.1.17 * rattus norvegicus 278.3 0.0416 17 PMID:15618015;PMID:16793941;PMID:17928680;PMID:4750769;PMID:7358199 -4.3.1.17 * rhizomucor miehei 7.35 7.35 1 PMID:26367174 -4.3.1.18 * escherichia coli 100.0 100.0 1 PMID:10601247 -4.3.1.18 * gallus gallus 1.39 0.094 9 PMID:17254537;PMID:17977854 -4.3.1.18 * klebsiella pneumoniae 12.0 6.145 2 PMID:32169 -4.3.1.18 * salmonella enterica subsp. enterica serovar typhimurium 2.12 2.105 2 PMID:21668644 -4.3.1.19 * arabidopsis thaliana 400.0 400.0 1 PMID:11106492 -4.3.1.19 * bacillus subtilis 23000.0 23000.0 1 PMID:24324624 -4.3.1.19 * capra hircus 0.52 0.52 1 PMID:5065257 -4.3.1.19 * cereibacter sphaeroides 48.3 48.3 1 PMID:4539055 -4.3.1.19 * corynebacterium glutamicum 89000.0 48750.0 2 PMID:24324624 -4.3.1.19 * escherichia coli 171000.0 220.0 6 PMID:1096954;PMID:2005118;PMID:240428;PMID:24324624;PMID:30259222;PMID:4573981;PMID:4582943 -4.3.1.19 * geobacter sulfurreducens 0.189 0.189 1 PMID:18245290 -4.3.1.19 * morganella morganii 318.0 200.3 2 * -4.3.1.19 * pseudomonas putida 106000.0 53001.05 2 PMID:24324624;PMID:4814721 -4.3.1.19 * rattus norvegicus 989.0 989.0 1 PMID:2313037 -4.3.1.19 * salmonella enterica subsp. enterica serovar typhimurium 683.0 683.0 1 PMID:368068 -4.3.1.19 * spinacia oleracea 7.3 4.15 2 PMID:5423384 -4.3.1.19 * staphylococcus aureus 7400.0 4435.0 2 PMID:24324624 -4.3.1.19 * streptomyces griseus 1000.0 1000.0 1 PMID:24324624 -4.3.1.2 * citrobacter amalonaticus 282.0 230.5 2 PMID:7576557 -4.3.1.2 * citrobacter freundii 162.0 162.0 1 PMID:7765982 -4.3.1.2 * clostridium tetanomorphum 280.0 210.5 2 PMID:1420191 -4.3.1.2 * escherichia coli 21.3 21.3 1 * -4.3.1.2 * fusobacterium varium 137.0 137.0 1 PMID:11506174 -4.3.1.2 * morganella morganii 296.0 296.0 1 PMID:7765982 -4.3.1.20 * paracoccus denitrificans 7.15 7.15 1 PMID:16749162 -4.3.1.23 * chryseobacterium luteum sp. nov 0.8 0.8 1 PMID:35352477 -4.3.1.23 * rivularia sp. pcc 7116 1.45 1.45 1 PMID:35352477 -4.3.1.23 * zea mays 0.00075 0.00044 2 PMID:20480387 -4.3.1.24 * bambusa oldhamii 3.78 3.76 7 PMID:20064614 -4.3.1.24 * centaurea depressa 34.9 34.9 1 PMID:27246528 -4.3.1.24 * cucurbita pepo 26.6 26.6 1 * -4.3.1.24 * cyathobasis fruticulosa 98.6 98.6 1 PMID:27956861 -4.3.1.24 * dolichospermum flos-aquae 52.2 48.45 2 PMID:31581382 -4.3.1.24 * ephedra sinica 7.83e-05 4.49e-05 2 PMID:19043198 -4.3.1.24 * glycine max 0.425 0.425 1 PMID:7197898 -4.3.1.24 * limnospira platensis 176.7 146.7 2 PMID:31581382 -4.3.1.24 * rhodotorula glutinis 145.0 4.23 7 PMID:22235485 -4.3.1.24 * trichormus variabilis 1.7 1.45 2 PMID:18556022;PMID:23999738 -4.3.1.24 * zea mays 7.14 3.5827999999999998 2 PMID:19082600;PMID:25947617 -4.3.1.25 * cutaneotrichosporon cutaneum 0.33 0.33 1 * -4.3.1.25 * rhodotorula glutinis 2.5 2.5 1 PMID:985816 -4.3.1.27 * delftia sp. ht23 21.3 21.1 3 PMID:20843822;PMID:25715785 -4.3.1.29 * salmonella enterica subsp. enterica 6.2 6.2 1 PMID:23836865 -4.3.1.3 * achromobacter liquidum 63.0 63.0 1 PMID:240693 -4.3.1.3 * pseudomonas putida 70.4 70.4 1 PMID:8251759 -4.3.1.3 * pseudomonas sp. 9.1 3.75 8 PMID:4622230 -4.3.1.3 * rattus norvegicus 9.94 5.1 4 PMID:15144042;PMID:4207867;PMID:5116 -4.3.1.3 * streptomyces griseus 20.7 20.7 1 PMID:8507666 -4.3.1.4 * sus scrofa 25.0 25.0 1 PMID:7374505 -4.3.1.6 * anaerotignum propionicum 1033.0 1033.0 1 PMID:15670161 -4.3.1.7 * clostridium sp. 35.0 24.55 2 PMID:186123;PMID:4297225 -4.3.1.7 * escherichia coli 55.1 34.5 2 PMID:19762342;PMID:33657 -4.3.1.7 * salmonella enterica subsp. enterica serovar typhimurium 25.3 25.3 1 PMID:1550360 -4.3.1.9 * agrobacterium tumefaciens 372.0 372.0 1 * -4.3.1.9 * soil bacterium 140.0 140.0 1 * -4.3.2.1 * bos taurus 23.0 23.0 1 PMID:5000445 -4.3.2.1 * chlamydomonas reinhardtii 0.38 0.38 1 PMID:588268 -4.3.2.1 * corynebacterium glutamicum 8.6 8.6 1 * -4.3.2.1 * homo sapiens 4227.0 10.3 5 PMID:11092456;PMID:21667091;PMID:6784763 -4.3.2.1 * ovis aries 0.0012 0.0012 1 PMID:19818875 -4.3.2.1 * pyrococcus furiosus 0.003 0.003 1 * -4.3.2.1 * saccharolobus solfataricus 0.006 0.0045000000000000005 2 * -4.3.2.2 * artemia sp. 2.4 2.4 1 PMID:6630197 -4.3.2.2 * bacillus subtilis 1.75 1.05 4 PMID:17600142;PMID:18237141 -4.3.2.2 * escherichia coli 16.47 10.559999999999999 2 PMID:17531264 -4.3.2.2 * halobacterium salinarum 40.0 40.0 1 PMID:9457844 -4.3.2.2 * haloferax volcanii 20.0 20.0 1 PMID:9457844 -4.3.2.2 * homo sapiens 23.3 3.8 13 PMID:15471876;PMID:16973378;PMID:21210713;PMID:23714113 -4.3.2.2 * rattus norvegicus 11.0 11.0 1 PMID:3689310 -4.3.2.3 * burkholderia cepacia 3.92 3.92 1 PMID:14506266 -4.3.2.3 * cicer arietinum 8.6 8.6 1 PMID:11161040 -4.3.2.3 * phaseolus vulgaris 4.439 4.439 1 PMID:16333637 -4.3.2.3 * rattus norvegicus 191.0 191.0 1 PMID:7492331 -4.3.2.5 * bos taurus 12000.0 6255.0 2 PMID:2207061 -4.3.2.5 * homo sapiens 0.53 0.53 1 PMID:12699694 -4.3.2.5 * rattus norvegicus 57.24 4.5 3 PMID:1898062;PMID:2357219 -4.3.2.5 * xenopus laevis 16000000.0 128000.0 4 PMID:10377242;PMID:2265607 -4.3.2.9 * homo sapiens 100.0 0.565 8 PMID:12447480;PMID:18515354;PMID:20110353;PMID:29601;PMID:5781001 -4.3.2.9 * musca domestica 70.7 70.7 1 * -4.3.2.9 * rattus norvegicus 181.0 39.0 6 PMID:4735346 -4.3.3.1 * flavobacterium saccharophilum 10.73 10.73 1 PMID:4093450 -4.3.3.1 * stenotrophomonas maltophilia 13.94 6.973129999999999 2 PMID:19795222 -4.3.3.6 * geobacillus sp. h6a 0.00821 0.00481 2 PMID:35350642 -4.3.3.6 * plasmodium berghei 0.233 0.0013 7 PMID:22244765 -4.3.3.6 * plasmodium falciparum 0.26 0.0010999999999999998 8 PMID:20837012;PMID:22244765 -4.3.3.7 * agrobacterium tumefaciens 174.0 174.0 1 PMID:22949190 -4.3.3.7 * bacillus anthracis 33.0 7.0 4 PMID:19194017 -4.3.3.7 * bacillus subtilis 458.0 458.0 1 PMID:4215809 -4.3.3.7 * escherichia coli 500.8 50.905 4 PMID:14580236;PMID:15066435;PMID:22644522;PMID:4910051 -4.3.3.7 * shewanella benthica 104.0 104.0 1 PMID:21045309 -4.3.3.7 * streptococcus pneumoniae 1.61 1.21 2 PMID:20057065 -4.3.3.7 * vibrio cholerae 112.0 93.8 2 PMID:29337198 -4.3.99.4 * oleidesulfovibrio alaskensis 22.7 22.7 1 PMID:24854437 -4.4.1.1 * aspergillus carneus 59.71 54.21 2 PMID:26316161 -4.4.1.1 * aspergillus fumigatus 13.8 13.8 1 PMID:26453470 -4.4.1.1 * lactococcus lactis 11.5 5.78235 2 PMID:10620674;PMID:16535512 -4.4.1.1 * leishmania major 0.49 0.49 1 PMID:24410980 -4.4.1.1 * leishmania mexicana 0.49 0.49 1 PMID:24410980 -4.4.1.1 * rattus norvegicus 24.0 17.0 2 PMID:22093698;PMID:6364702 -4.4.1.1 * streptomyces phaeochromogenes 2.6 2.6 1 PMID:2821351;PMID:6432781 -4.4.1.11 * aeromonas sp. 31.0 31.0 1 * -4.4.1.11 * aspergillus carneus 0.0028 0.0028 1 PMID:19048340 -4.4.1.11 * aspergillus flavipes 0.723 0.43200000000000005 10 PMID:19048340;PMID:19455514 -4.4.1.11 * aspergillus flavus 0.0016 0.0016 1 PMID:19048340 -4.4.1.11 * aspergillus niger 0.0019 0.0019 1 PMID:19048340 -4.4.1.11 * aspergillus ochraceus 0.0014 0.0014 1 PMID:19048340 -4.4.1.11 * aspergillus oryzae 0.0015 0.0015 1 PMID:19048340 -4.4.1.11 * aspergillus parasiticus 0.0013 0.0013 1 PMID:19048340 -4.4.1.11 * aspergillus subolivaceus 0.0015 0.0015 1 PMID:19048340 -4.4.1.11 * aspergillus tamarii 0.0014 0.0014 1 PMID:19048340 -4.4.1.11 * brevibacterium aurantiacum 123.0 60.0 5 PMID:19251895 -4.4.1.11 * citrobacter freundii 10.2 10.1 2 PMID:15901718;PMID:24303205 -4.4.1.11 * citrobacter intermedius 0.26 0.26 1 * -4.4.1.11 * cladosporium oxysporum 0.0015 0.0015 1 PMID:19048340 -4.4.1.11 * clostridium sporogenes 12.8 12.8 1 PMID:24303205 -4.4.1.11 * clostridium tetani 16.6 16.6 1 PMID:24303205 -4.4.1.11 * entamoeba histolytica 0.44 0.4 2 PMID:12920135 -4.4.1.11 * fusarium oxysporum 0.002 0.002 1 PMID:19048340 -4.4.1.11 * fusarium solani 0.0023 0.0023 1 PMID:19048340 -4.4.1.11 * humicola fuscoatra 0.002 0.002 1 PMID:19048340 -4.4.1.11 * idiomarina sp. 108.0 108.0 1 PMID:26308011 -4.4.1.11 * microdochium nivale 0.0021 0.0021 1 PMID:19048340 -4.4.1.11 * mucor racemosus 0.0017 0.0017 1 PMID:19048340 -4.4.1.11 * mus musculus 57.0 40.0 7 PMID:15313919;PMID:16510603 -4.4.1.11 * penicillium chrysogenum 0.0026 0.0026 1 PMID:19048340 -4.4.1.11 * penicillium citrinum 0.0014 0.0014 1 PMID:19048340 -4.4.1.11 * penicillium digitatum 0.0017 0.0017 1 PMID:19048340 -4.4.1.11 * penicillium egyptiacum 0.0019 0.0019 1 PMID:19048340 -4.4.1.11 * porphyromonas gingivalis 5.0 5.0 1 PMID:24303205 -4.4.1.11 * pseudomonas putida 57.0 45.3 5 PMID:16012835;PMID:6742420;PMID:8616859;PMID:955094 -4.4.1.11 * pseudomonas sp. 105.8 81.015 2 PMID:37305655 -4.4.1.11 * scopulariopsis brevicaulis 0.0028 0.0028 1 PMID:19048340 -4.4.1.11 * streptomyces sp. dmmmh60 260.5 160.55 2 * -4.4.1.11 * treponema denticola 36.6 36.6 1 PMID:15845368 -4.4.1.11 * trichoderma koningii 0.002 0.002 1 PMID:19048340 -4.4.1.13 * arabidopsis thaliana 24.5 24.5 1 PMID:8973544 -4.4.1.13 * brassica oleracea 7.69 7.69 1 PMID:10794613 -4.4.1.13 * echinochloa colona 11.9 11.9 1 * -4.4.1.13 * escherichia coli 248.0 231.5 2 PMID:2821350;PMID:3513164;PMID:7049234 -4.4.1.13 * homo sapiens 2.15 1.1564999999999999 2 PMID:25231977 -4.4.1.13 * lactococcus lactis 2.1 2.1 1 PMID:16535166 -4.4.1.13 * lathyrus oleraceus 0.0091 0.0091 1 * -4.4.1.13 * monieza expansa 0.037 0.037 1 PMID:10779568 -4.4.1.13 * rattus norvegicus 25.0 0.27585 6 PMID:16846239;PMID:3003507;PMID:4008484;PMID:721818;PMID:8286953 -4.4.1.13 * saccharomyces cerevisiae 1258.0 1258.0 1 PMID:21478306 -4.4.1.13 * salmonella enterica subsp. enterica serovar typhimurium 7.9 7.9 1 * -4.4.1.13 * spinacia oleracea 1.226 0.6685 2 PMID:1898098;PMID:5569129 -4.4.1.13 * vachellia farnesiana 40.0 40.0 1 PMID:241329 -4.4.1.14 * cicer arietinum 8e-08 8e-08 1 * -4.4.1.14 * cucurbita maxima 0.22 0.22 1 * -4.4.1.14 * cucurbita pepo 1.5 1.04 2 PMID:1995630;PMID:9535697 -4.4.1.14 * gossypium hirsutum 2.78 2.315 2 PMID:21742672 -4.4.1.14 * malus domestica 6900.0 6900.0 1 PMID:10704193 -4.4.1.14 * malus sylvestris 1.7 1.7 1 PMID:16667960 -4.4.1.14 * musa sp. 6.7e-08 1.8999999999999998e-08 4 PMID:17185740 -4.4.1.14 * solanum lycopersicum 0.2 0.2 1 PMID:16666248 -4.4.1.14 * vigna radiata 0.35 0.35 1 PMID:3401016 -4.4.1.14 * vigna radiata var. radiata 4.366e-07 3.4165e-07 4 * -4.4.1.15 * escherichia coli 56.3 34.65 2 PMID:3908101 -4.4.1.15 * oryza sativa japonica group 43.36 21.6875 2 * -4.4.1.15 * pseudomonas putida 0.001594 0.001594 1 PMID:18825405 -4.4.1.15 * scenedesmus fuscus 0.21 0.21 1 * -4.4.1.15 * solanum lycopersicum 5.784 5.784 1 PMID:18825405 -4.4.1.15 * spinacia oleracea 0.01 0.01 1 * -4.4.1.15 * synechococcus elongatus 0.035 0.018 10 PMID:16999035 -4.4.1.16 * citrobacter freundii 6.47 6.47 1 * -4.4.1.16 * escherichia coli 5.6 5.6 1 PMID:10329673 -4.4.1.16 * leuconostoc mesenteroides 0.26 0.175 2 PMID:35122135 -4.4.1.16 * mus musculus 29.0 29.0 1 PMID:10692412 -4.4.1.16 * sus scrofa 37.0 37.0 1 PMID:2821348;PMID:6461656 -4.4.1.16 * trypanosoma brucei 1500.0 800.0 6 PMID:19968861 -4.4.1.19 * methanocaldococcus jannaschii 2.4 2.4 1 PMID:11830598 -4.4.1.19 * xanthobacter autotrophicus 487.0 487.0 1 PMID:29414784 -4.4.1.2 * aspergillus fumigatus 16.6 12.540000000000001 2 PMID:23568204 -4.4.1.20 * cavia porcellus 0.00786 0.00786 1 PMID:2833313 -4.4.1.20 * homo sapiens 35.0 2.9375 4 PMID:1425677;PMID:20980252;PMID:7663172;PMID:8446623 -4.4.1.20 * mus musculus 30.5 30.5 1 PMID:2172733 -4.4.1.20 * rattus norvegicus 28.0 0.0813 5 PMID:14637132;PMID:1517222;PMID:18440824 -4.4.1.22 * paracoccus denitrificans 350.0 350.0 1 PMID:11741920 -4.4.1.23 * mycobacterium sp. 615.0 379.0 2 PMID:12949106 -4.4.1.23 * mycobacterium sp. js623 0.645 0.068 12 PMID:20363787 -4.4.1.23 * ochrobactrum sp. 4.6 3.7 3 PMID:16672529 -4.4.1.23 * pseudomonas putida 4.4 3.4 3 PMID:16672529 -4.4.1.24 * chromohalobacter israelensis 0.2 0.165 2 PMID:20007648 -4.4.1.24 * cupriavidus pinatubonensis 0.016 0.016 1 PMID:20150239 -4.4.1.24 * paracoccus pantotrophus 0.3 0.3 1 PMID:15758220 -4.4.1.25 * roseovarius nubinhibens 0.02 0.02 1 PMID:20150239 -4.4.1.28 * brassica napus 0.066 0.066 1 PMID:23180220 -4.4.1.28 * methanocaldococcus jannaschii 55.8 55.8 1 PMID:15683250 -4.4.1.28 * prevotella intermedia 4.2 4.2 1 PMID:19832801 -4.4.1.3 * alcaligenes faecalis 902.0 902.0 1 PMID:29561599 -4.4.1.3 * alcaligenes sp. 390.1 390.1 1 PMID:16534905 -4.4.1.3 * halodesulfovibrio aestuarii 1391.0 1391.0 1 PMID:29561599 -4.4.1.3 * phaeobacter inhibens 83.83 83.83 1 PMID:36808192 -4.4.1.3 * ruegeria pomeroyi 1.08 1.05 2 PMID:25993446 -4.4.1.35 * brassica oleracea var. italica 29.8 18.75 2 PMID:10794613 -4.4.1.4 * allium cepa 119.7 71.45 2 PMID:10759524;PMID:16665807 -4.4.1.4 * allium fistulosum 97.5 97.5 1 * -4.4.1.4 * allium sativum 2989.0 126.0 9 PMID:10193205;PMID:16665807;PMID:17262455;PMID:22374998;PMID:26374695;PMID:3740854;PMID:7979352 -4.4.1.4 * allium tuberosum 152.8 152.8 1 PMID:9799098 -4.4.1.4 * cupriavidus necator 209.0 209.0 1 PMID:30505192 -4.4.1.4 * ensifer adhaerens 102.5 96.25 2 PMID:21906328 -4.4.1.4 * penicillium hirsutum 1.17 1.17 1 * -4.4.1.4 * petiveria alliacea 6.42 6.42 1 PMID:19789290 -4.4.1.42 * enterobacteria phage t3 248.2 248.2 1 PMID:110588 -4.4.1.42 * escherichia coli 28.3 15.685 2 * -4.4.1.42 * homo sapiens 0.061 0.061 1 PMID:4272661 -4.4.1.42 * sus scrofa 0.117 0.108 3 PMID:4272661 -4.4.1.5 * allium cepa 356.0 178.97 2 PMID:19734676 -4.4.1.5 * aloe vera 200.0 200.0 1 PMID:2076100 -4.4.1.5 * aspergillus niger 22.7 22.7 1 PMID:3123469 -4.4.1.5 * bos taurus 425.0 425.0 1 PMID:11513094 -4.4.1.5 * brassica juncea 188.3 188.3 1 PMID:2037046 -4.4.1.5 * chlamydomonas reinhardtii 33.24 33.24 1 * -4.4.1.5 * cyberlindnera mrakii 3570.0 3570.0 1 * -4.4.1.5 * homo sapiens 1830.0 110.0 9 PMID:15843146;PMID:18946510;PMID:24856185;PMID:443539;PMID:7154966;PMID:8489699 -4.4.1.5 * leishmania donovani 3400.0 1700.17 2 PMID:16236261 -4.4.1.5 * leishmania major 0.085 0.085 1 PMID:19076214 -4.4.1.5 * macaca radiata 925.0 925.0 1 PMID:3109489 -4.4.1.5 * mus musculus 2200.0 0.247 11 PMID:1138914;PMID:18720345;PMID:7154967;PMID:880305 -4.4.1.5 * mytilus galloprovincialis 83.2 83.2 1 * -4.4.1.5 * neisseria meningitidis 390.0 390.0 3 PMID:15270717 -4.4.1.5 * onchocerca volvulus 284.0 194.5 2 PMID:11171039 -4.4.1.5 * oryctolagus cuniculus 681.0 681.0 1 PMID:697868 -4.4.1.5 * oryza sativa japonica group 120.0 64.15 2 PMID:24661284 -4.4.1.5 * plasmodium falciparum 150.0 120.0 2 PMID:14623080;PMID:15843146 -4.4.1.5 * pseudomonas aeruginosa 571.0 571.0 3 PMID:15270717 -4.4.1.5 * pseudomonas putida 359.7 359.7 1 PMID:3101683 -4.4.1.5 * rattus norvegicus 2415.0 191.0 15 PMID:21783929;PMID:6173571;PMID:953039 -4.4.1.5 * saccharomyces cerevisiae 1130.0 1046.5 2 PMID:393249 -4.4.1.5 * streptococcus mutans 46.2 46.2 1 PMID:17720789 -4.4.1.5 * sus scrofa 957.0 558.0 2 PMID:4628223;PMID:921763 -4.4.1.5 * trypanosoma cruzi 0.042 0.038 3 PMID:19076214 -4.4.1.5 * yersinia pestis 618.0 618.0 3 PMID:15270717 -4.4.1.9 * arabidopsis thaliana 62.1 31.25 2 PMID:10889265 -4.4.1.9 * geobacillus stearothermophilus 483.0 483.0 1 PMID:16233442 -4.4.1.9 * hevea brasiliensis 0.0043 0.00052 3 PMID:19409582 -4.4.1.9 * lathyrus latifolius 132.0 132.0 1 * -4.4.1.9 * lupinus sp. 323.8 43.5 3 PMID:1055433;PMID:5769995 -4.4.1.9 * oryza sativa 181.0 111.3 3 PMID:19181864 -4.4.1.9 * solanum tuberosum 12830.0 49.5 5 PMID:10795315;PMID:11575729 -4.4.1.9 * spinacia oleracea 212.0 157.0 3 PMID:10889265 -4.4.1.9 * tetranychus urticae 6.84 6.84 1 PMID:24843024 -4.4.1.9 * vicia sativa 0.003 0.003 1 PMID:603055 -4.4.1.9 * vicia sativa subsp. nigra 120.0 120.0 1 * -4.4.1.9 * xanthium pennsylvanicum 38.0 38.0 1 * -4.4.1.9 * zonocerus variegatus 0.0375 0.01983 2 PMID:17175447 -4.5.1.1 * anopheles dirus 0.149 0.149 1 PMID:10745163 -4.5.1.2 * pseudomonas putida 311.0 310.5 2 PMID:6427787 -4.5.1.3 * hyphomicrobium sp. 1.041 1.041 1 * -4.5.1.3 * methylophilus sp. 7.398 2.158 10 PMID:10075637 -4.5.1.3 * methylorubrum rhodesianum 0.0003138 0.0003138 1 PMID:31388925 -4.5.1.3 * niallia circulans 118.8 49.12 5 PMID:17687552;PMID:19277720 -4.5.1.4 * proteus mirabilis 0.00609 0.00556 3 * -4.6.1.1 * aeromonas hydrophila 6.3 3.55 2 PMID:9642185 -4.6.1.1 * bordetella pertussis 1685.0 608.0 5 PMID:1693922;PMID:2867778;PMID:2870055;PMID:2901413 -4.6.1.1 * bos taurus 100.0 26.175 4 PMID:13718;PMID:2034121;PMID:8784925 -4.6.1.1 * canis lupus familiaris 65.0 65.0 1 PMID:11665600 -4.6.1.1 * escherichia coli 32.0 0.665 3 PMID:18620542;PMID:2557591;PMID:6300054 -4.6.1.1 * haloactinopolyspora alba 0.000776 0.000776 1 * -4.6.1.1 * limnospira platensis 0.011 0.005679999999999999 2 PMID:11134014 -4.6.1.1 * mammalia 12.8 12.8 1 PMID:8663304 -4.6.1.1 * medicago sativa 630.0 630.0 1 PMID:3128270 -4.6.1.1 * mus musculus 0.000335 0.000335 3 PMID:18164588 -4.6.1.1 * mycobacterium tuberculosis 0.48 0.48 1 PMID:11431477 -4.6.1.1 * oryctolagus cuniculus 14.69 14.69 1 PMID:2034122 -4.6.1.1 * plasmodium falciparum 0.04 0.04 1 PMID:14607282 -4.6.1.1 * rattus norvegicus 920.0 493.5 2 PMID:11665600;PMID:9874775 -4.6.1.1 * rhizobium etli 0.0032 0.0032 1 PMID:12057950 -4.6.1.1 * saccharomyces cerevisiae 150.0 150.0 1 PMID:793584 -4.6.1.1 * synechocystis sp. 0.005816 0.002985 2 PMID:16573521 -4.6.1.1 * thermobifida halotolerans 0.000459 0.000459 1 * -4.6.1.1 * trypanosoma cruzi 9.4e-05 9.4e-05 1 PMID:12121994 -4.6.1.1 * turneriella parva 53.3 53.3 1 PMID:26398816 -4.6.1.12 * plasmodium falciparum 0.75 0.75 1 PMID:11389720 -4.6.1.13 * bacillus cereus 13.74 13.74 1 PMID:10986 -4.6.1.13 * bacillus sp. (in: firmicutes) 3560.0 3560.0 1 PMID:12600209 -4.6.1.13 * bacillus thuringiensis 1630.0 224.0 8 PMID:11912206;PMID:19369255;PMID:19548649 -4.6.1.13 * listeria monocytogenes 700.0 365.0 2 PMID:12488013 -4.6.1.13 * streptomyces antibioticus 16.1 16.1 1 PMID:7918603 -4.6.1.14 * trypanosoma brucei 11000000.0 5500.0 10 PMID:10491140;PMID:15254033;PMID:3759991;PMID:3782089;PMID:7651183;PMID:9476790 -4.6.1.15 * homo sapiens 0.01 0.01 1 PMID:16289032 -4.6.1.15 * rattus norvegicus 13.0 13.0 1 * -4.6.1.18 * bos taurus 22600.0 13.33 17 PMID:16933205;PMID:17914869;PMID:6784751 -4.6.1.18 * homo sapiens 35000.0 10300.0 3 PMID:11451444;PMID:6784751 -4.6.1.18 * sulfolobus acidocaldarius 3.52 3.52 1 PMID:7545905 -4.6.1.19 * aspergillus oryzae 366.6 366.6 1 PMID:1418689 -4.6.1.19 * bacteroides sp. 630.0 251.0 5 PMID:16644192 -4.6.1.19 * escherichia coli 223500.0 223500.0 1 PMID:8557629 -4.6.1.19 * magallana gigas 968.0 968.0 1 PMID:11582795 -4.6.1.19 * rhizopus niveus 1600.0 1600.0 2 PMID:11129577;PMID:12723605 -4.6.1.19 * trichoderma viride 583.0 583.0 1 PMID:11582795 -4.6.1.2 * arbacia punctulata 83.1 42.6 4 PMID:1674568;PMID:2891712;PMID:6134728;PMID:6469 -4.6.1.2 * bos taurus 38.0 2.68 12 PMID:16291256;PMID:1673683;PMID:1674569;PMID:1684292;PMID:18430586;PMID:6114859;PMID:8527937;PMID:9799554 -4.6.1.2 * chlamydomonas reinhardtii 0.914 0.405 3 PMID:30946781 -4.6.1.2 * drosophila melanogaster 5.6 5.6 1 PMID:18044974 -4.6.1.2 * homo sapiens 22.1 0.5725 8 PMID:10995472;PMID:11123935;PMID:11368154;PMID:12883009;PMID:15041475;PMID:2576855 -4.6.1.2 * ipomoea nil 4.8e-07 4.65e-07 2 PMID:18674925 -4.6.1.2 * rattus norvegicus 12.1 0.693 11 PMID:15023055;PMID:16592607;PMID:21491881;PMID:28767;PMID:31365 -4.6.1.2 * sus scrofa 1.38 0.53 3 PMID:19181745 -4.6.1.24 * pleurotus ostreatus 2350.0 2350.0 1 PMID:23832341 -4.6.1.6 * rattus norvegicus 0.0012 0.0012 1 PMID:2154193 -4.8.1.2 * fusarium vanettenii 25.0 25.0 1 PMID:36610228 -4.8.1.2 * pseudomonas chlororaphis 197.0 98.879 2 PMID:12773527 -4.8.1.2 * rhodococcus globerulus 2.18 1.13395 2 PMID:14556637 -4.8.1.2 * rhodococcus sp. n-771 3.92 3.92 1 PMID:16233624 -4.8.1.3 * sclerotinia sclerotiorum 0.175 0.08975 2 PMID:21036375 -4.98.1.1 * arabidopsis thaliana 4.8 3.94 2 PMID:30342111 -4.98.1.1 * bacillus subtilis 0.093 0.053000000000000005 4 PMID:15300829 -4.98.1.1 * bos taurus 0.959 0.6859999999999999 2 PMID:3702736;PMID:7173190 -4.98.1.1 * cereibacter sphaeroides 1.6 1.6 1 PMID:3702737;PMID:6983526 -4.98.1.1 * chironomidae 15.2 15.2 1 PMID:11451377 -4.98.1.1 * cyanidioschyzon merolae 0.0015 0.0015 1 PMID:23700350 -4.98.1.1 * gallus gallus 0.959 0.959 1 PMID:3702736 -4.98.1.1 * saccharomyces cerevisiae 0.447 0.447 1 PMID:3042776 -4.99.1.10 * chenopodium album 1.05e-06 5.27e-07 2 PMID:16228560 -4.99.1.2 * escherichia coli 0.06 0.06 1 PMID:3542021 -4.99.1.3 * archaeoglobus fulgidus 0.017 0.0105 2 PMID:16835730 -4.99.1.3 * methanobacter thermoautotrophicum 0.06 0.039 2 PMID:12686546 -4.99.1.3 * methanosarcina barkeri 0.122 0.12085 2 PMID:12686546;PMID:17584754 -4.99.1.3 * nitratidesulfovibrio vulgaris 22.0 2.75 6 PMID:18457416 -4.99.1.3 * priestia megaterium 1.4 1.4 1 PMID:12917443 -4.99.1.3 * synechocystis sp. 0.08 0.08 1 PMID:12917443 -4.99.1.4 * arabidopsis thaliana 38.5 0.0485 3 PMID:15545265;PMID:22414210 -4.99.1.4 * priestia megaterium 0.337 0.17020000000000002 2 PMID:12408752 -4.99.1.4 * saccharomyces cerevisiae 0.0311 0.0311 1 PMID:11980703 -4.99.1.4 * salmonella enterica 0.0656 0.0656 1 PMID:14595395 -5.1.1.1 * acidiphilium organovorum 191.0 191.0 1 * -5.1.1.1 * alkalihalophilus pseudofirmus 10500.0 7104.0 2 PMID:19269582 -5.1.1.1 * bacillus anthracis 295.0 295.0 1 PMID:19192393 -5.1.1.1 * caldanaerobacter subterraneus subsp. tengcongensis 1414.0 1414.0 1 PMID:23703245 -5.1.1.1 * chlamydomonas reinhardtii 3.8 3.8 1 PMID:17469227 -5.1.1.1 * enterococcus faecalis 2920.0 2920.0 1 PMID:3921052 -5.1.1.1 * escherichia coli 133.0 133.0 1 PMID:1939194 -5.1.1.1 * helicobacter pylori 61.8 61.8 1 PMID:17196222 -5.1.1.1 * ligilactobacillus salivarius 161.0 161.0 1 PMID:26543773 -5.1.1.1 * penaeus monodon 2807.0 1687.0 2 PMID:12431412 -5.1.1.1 * peribacillus psychrosaccharolyticus 650.0 650.0 1 PMID:10080917 -5.1.1.1 * procambarus clarkii 2044.0 2044.0 1 PMID:11026672 -5.1.1.1 * pseudomonas fluorescens 587.0 587.0 1 PMID:7763424 -5.1.1.1 * pseudomonas putida 42.6 16.5 3 PMID:22806802 -5.1.1.1 * pyrococcus horikoshii 49.5 38.85 2 PMID:30038603 -5.1.1.1 * salmonella enterica subsp. enterica serovar typhimurium 910.0 466.0 2 PMID:3524677;PMID:6391537 -5.1.1.1 * shigella dysenteriae 209.0 209.0 1 PMID:11676496 -5.1.1.1 * streptomyces coelicolor 104.0 85.0 2 PMID:28042035 -5.1.1.1 * tolypocladium inflatum 143.0 143.0 1 PMID:8175682 -5.1.1.10 * achromobacter obae 627.0 535.0 2 PMID:26206345 -5.1.1.10 * aeromonas caviae 1250.0 1250.0 1 PMID:6427786 -5.1.1.10 * brucella anthropi 1225.0 253.5 4 PMID:26206345 -5.1.1.10 * citreicella sp. se45 772.0 726.5 2 PMID:26206345 -5.1.1.10 * glutamicibacter nicotianae 422.0 302.0 2 PMID:26206345 -5.1.1.10 * janibacter sp. htcc2649 63.0 55.0 2 PMID:26206345 -5.1.1.10 * mesorhizobium opportunistum 133.0 86.0 2 PMID:26206345 -5.1.1.10 * mycolicibacterium vanbaalenii 94.0 57.0 2 PMID:26206345 -5.1.1.10 * pseudomonas putida 1423.0 209.0 13 PMID:17028872;PMID:5788493;PMID:8320235 -5.1.1.10 * pseudomonas taetrolens 1120.0 1120.0 1 PMID:19300994 -5.1.1.10 * pyrococcus horikoshii 22.7 10.5 5 PMID:25963389 -5.1.1.10 * sinorhizobium medicae 1072.0 796.0 2 PMID:26206345 -5.1.1.10 * sinorhizobium meliloti 260.0 106.0 4 PMID:26206345 -5.1.1.10 * thermococcus kodakarensis 133.0 85.8 4 PMID:33468590 -5.1.1.11 * brevibacillus brevis 0.019 0.019 1 PMID:4016097 -5.1.1.12 * acetoanaerobium sticklandii 383.8 383.8 1 PMID:10715017 -5.1.1.13 * anadara broughtonii 22.6 14.995000000000001 2 PMID:12568809 -5.1.1.13 * bifidobacterium bifidum 4.75 4.75 1 PMID:15606767 -5.1.1.13 * mus musculus 460.0 460.0 1 PMID:20133766 -5.1.1.13 * saccoglossus kowalevskii 4.0 3.475 4 PMID:30902582 -5.1.1.13 * streptococcus thermophilus 26.8 19.9 3 PMID:1907199;PMID:25596033 -5.1.1.13 * thermococcus litoralis 3870.0 1590.0 3 PMID:27438592 -5.1.1.13 * thermoplasma acidophilum 1160.0 1160.0 1 PMID:11181048 -5.1.1.15 * achromobacter obae 627.0 16.35 12 PMID:26206345;PMID:27544766;PMID:7160482 -5.1.1.15 * brucella anthropi 2337.0 63.0 7 PMID:26206345;PMID:29897155 -5.1.1.15 * citreicella sp. se45 772.0 11.4 12 PMID:26206345;PMID:27544766 -5.1.1.15 * ensifer sp. 23-3 365.0 365.0 1 PMID:28929416 -5.1.1.15 * glutamicibacter nicotianae 422.0 302.0 2 PMID:26206345 -5.1.1.15 * janibacter sp. htcc2649 63.0 55.0 2 PMID:26206345 -5.1.1.15 * mesorhizobium opportunistum 133.0 86.0 2 PMID:26206345 -5.1.1.15 * mycolicibacterium vanbaalenii 94.0 57.0 2 PMID:26206345 -5.1.1.15 * sinorhizobium medicae 1072.0 796.0 2 PMID:26206345 -5.1.1.15 * sinorhizobium meliloti 260.0 106.0 4 PMID:26206345 -5.1.1.17 * amycolatopsis lactamdurans 0.000727 0.0004085 2 * -5.1.1.17 * streptomyces clavuligerus 7.77 5.81 2 PMID:2804141 -5.1.1.18 * caenorhabditis elegans 0.00146 0.00146 1 PMID:27458110 -5.1.1.18 * homo sapiens 16.2 0.20550000000000002 4 PMID:18812225;PMID:23112234;PMID:27458110 -5.1.1.18 * mus musculus 16.2 16.2 1 PMID:18812225 -5.1.1.18 * oryza sativa 0.13 0.13 1 PMID:19249065 -5.1.1.18 * pyrobaculum islandicum 13.6 13.6 1 PMID:17965169 -5.1.1.18 * pyrococcus horikoshii 41.2 36.3 2 PMID:30038603 -5.1.1.18 * rattus norvegicus 0.083 0.083 1 PMID:9892700 -5.1.1.2 * thermococcus kodakarensis 133.0 85.8 4 PMID:33468590 -5.1.1.21 * lentilactobacillus buchneri 221.0 72.9 16 PMID:24039265 -5.1.1.21 * lentilactobacillus otakiensis 34.3 34.3 1 PMID:24039265 -5.1.1.21 * leuconostoc gasicomitatum 0.00681 0.00283 3 PMID:30057575 -5.1.1.21 * leuconostoc mesenteroides subsp. mesenteroides 0.00246 0.00101 3 PMID:30057575 -5.1.1.21 * leuconostoc pseudomesenteroides 0.00107 0.00026 3 PMID:30057575 -5.1.1.21 * limosilactobacillus fermentum 0.0253 0.0234 3 PMID:30057575 -5.1.1.21 * limosilactobacillus vaginalis 0.00148 0.0011795 2 PMID:30057575 -5.1.1.21 * weissella paramesenteroides 0.0335 0.00836 3 PMID:30057575 -5.1.1.3 * bacillus subtilis 42.0 27.0 2 PMID:15502318;PMID:9604005 -5.1.1.3 * burkholderia cenocepacia 2.4 2.4 1 PMID:27898711 -5.1.1.3 * lactiplantibacillus plantarum 2043.0 1022.265 2 PMID:23228473 -5.1.1.3 * levilactobacillus brevis 216.0 216.0 1 PMID:7772825 -5.1.1.3 * limosilactobacillus fermentum 161.0 101.85 4 PMID:14961753;PMID:5363991;PMID:8385993 -5.1.1.3 * mycolicibacterium smegmatis 3.0 3.0 1 PMID:18177305 -5.1.1.3 * pediococcus pentosaceus 26.0 26.0 1 * -5.1.1.3 * saccoglossus kowalevskii 69.7 3.475 8 PMID:30902582 -5.1.1.4 * acetoanaerobium sticklandii 742.0 600.0 3 PMID:13475375;PMID:3755058;PMID:5722267 -5.1.1.5 * proteus mirabilis 2828.0 1698.0 2 * -5.1.1.5 * uncultured bacterium 3.61 2.645 2 PMID:19502445 -5.1.1.7 * escherichia coli 1.18 0.574 3 PMID:20057066 -5.1.1.7 * kitasatospora setae 4.93 3.27 2 PMID:23518570 -5.1.1.7 * priestia megaterium 2.8 2.8 1 PMID:4989322 -5.1.1.8 * pseudomonas putida 164.0 154.0 3 PMID:14189888;PMID:5469165 -5.1.1.9 * pseudomonas graveolens 1250.0 1250.0 1 PMID:5779761 -5.1.1.9 * pseudomonas taetrolens 70.2 70.2 1 PMID:20564572 -5.1.2.1 * clostridium butyricum 4.16 4.16 1 PMID:4810054 -5.1.2.2 * pseudomonas putida 195.0 96.500325 4 PMID:27557723;PMID:4989844 -5.1.2.3 * escherichia coli 3.35 2.575 2 PMID:3286611;PMID:368024 -5.1.2.3 * neurospora crassa 52.4 52.4 1 PMID:1830048 -5.1.3.1 * bos taurus 6570.0 3289.525 2 PMID:3987693 -5.1.3.1 * spinacia oleracea 11610.0 11610.0 1 PMID:9733539 -5.1.3.10 * salmonella enterica subsp. enterica serovar enteritidis 0.025 0.025 1 PMID:5924649 -5.1.3.11 * bacillota bacterium 58.91 58.91 1 PMID:28252294 -5.1.3.11 * bacteroides fragilis 79.7 61.8 5 PMID:19202279;PMID:28252294 -5.1.3.11 * butyrivibrio sp. ae2015 25.85 25.85 1 PMID:28252294 -5.1.3.11 * caldicellulosiruptor obsidiansis 93.6 93.6 1 PMID:27873314 -5.1.3.11 * caldicellulosiruptor saccharolyticus 74.39 7.185 12 PMID:21691788;PMID:22123300;PMID:23801120;PMID:27080880 -5.1.3.11 * dictyoglomus thermophilum 160.1 81.81 2 PMID:31401280 -5.1.3.11 * dictyoglomus turgidum 90.58 16.8 3 PMID:22782272 -5.1.3.11 * dyadobacter fermentans 46.91 46.91 1 PMID:28252294 -5.1.3.11 * rhodothermus marinus 311.34 311.34 2 PMID:28252294 -5.1.3.11 * roseburia intestinalis 77.3 77.3 1 PMID:32684457 -5.1.3.11 * ruminococcus albus 51.0 33.605000000000004 8 PMID:17612504;PMID:18392616;PMID:19202279;PMID:19330485;PMID:28252294 -5.1.3.11 * thermoanaerobacterium saccharolyticum 29.8 15.48 3 * -5.1.3.11 * thermoanaerobacterium thermosaccharolyticum 82.1 82.1 1 PMID:31401280 -5.1.3.11 * treponema brennaborense 208.5 208.5 1 PMID:34231359 -5.1.3.11 * uncultured bacterium 201.0 41.7 8 PMID:25487892 -5.1.3.11 * winmispira thermophila 29.2 7.05 12 PMID:23801120 -5.1.3.14 * bacillus cereus 0.7 0.7 1 PMID:418068 -5.1.3.14 * escherichia coli 7.08 7.08 1 PMID:381306;PMID:7048002 -5.1.3.14 * rattus norvegicus 10.9 0.739 4 PMID:15135418;PMID:4337336;PMID:9305887 -5.1.3.18 * candidatus methylacidiphilum fumarolicum 0.12 0.12 1 PMID:33075338 -5.1.3.2 * bifidobacterium bifidum 41.8 41.8 1 * -5.1.3.2 * bos taurus 210.0 138.0 2 PMID:845161 -5.1.3.2 * escherichia coli 233.3 216.7 3 PMID:14235524;PMID:2008433 -5.1.3.2 * galdieria sulphuraria 42.0 42.0 1 * -5.1.3.2 * kluyveromyces marxianus 73.0 73.0 1 PMID:14686919 -5.1.3.2 * lathyrus oleraceus 53.3 19.8 15 PMID:19754426 -5.1.3.2 * magallana gigas 3.48 3.48 1 PMID:29844279 -5.1.3.2 * mycobacterium tuberculosis 7.2 3.99 2 PMID:28403215 -5.1.3.2 * saccharomyces cerevisiae 31.8 16.7 2 PMID:16452467;PMID:6292668;PMID:6987227 -5.1.3.2 * streptococcus pneumoniae 0.0183 0.01185 2 PMID:29534667 -5.1.3.2 * thermotoga maritima 192.4 131.05 2 PMID:26344854 -5.1.3.2 * vicia faba 7.9 7.9 1 * -5.1.3.20 * escherichia coli 2.7 1.350435 2 PMID:17316025;PMID:7929099 -5.1.3.21 * levilactobacillus brevis 1710.0 1710.0 1 PMID:7796915 -5.1.3.3 * acinetobacter calcoaceticus 230.0 215.0 2 PMID:3531172 -5.1.3.3 * aspergillus niger 4.6 4.6 1 PMID:7317442 -5.1.3.3 * bos taurus 14.03 7.8549999999999995 2 * -5.1.3.3 * rattus norvegicus 745.0 512.0 7 PMID:6630166 -5.1.3.30 * dorea sp. cag:317 806.0 806.0 1 * -5.1.3.30 * ruminiclostridium cellulolyticum 2246.0 2246.0 1 PMID:30486886 -5.1.3.30 * ruminococcus sp. 60.8 60.8 1 PMID:31797048 -5.1.3.30 * ruminococcus sp. 5_1_39bfaa 58.6 41.33 2 * -5.1.3.30 * treponema primitia 227.5 227.5 1 PMID:25809188 -5.1.3.31 * caballeronia fortuita 801.0 360.0 4 PMID:31330210 -5.1.3.31 * pseudomonas sp. 30.0 30.0 1 * -5.1.3.37 * azotobacter vinelandii 4.9 4.4 3 PMID:9812987 -5.1.3.4 * escherichia coli 34.0 34.0 1 PMID:9548961 -5.1.3.4 * klebsiella aerogenes 12.5 12.5 1 PMID:13549442 -5.1.3.5 * lathyrus oleraceus 49.0 21.1 7 PMID:19754426 -5.1.3.7 * bacillus subtilis 565.0 565.0 1 * -5.1.3.7 * priestia megaterium 7.09 7.09 1 PMID:3100914 -5.1.3.7 * streptococcus pneumoniae 0.0185 0.0185 1 PMID:29534667 -5.1.3.7 * thermotoga maritima 93.7 71.2 2 PMID:26344854 -5.1.3.7 * vibrio vulnificus 0.0206 0.01625 2 PMID:18227162 -5.1.3.8 * anabaena sp. ch1 525.8 54.8 17 PMID:17292397;PMID:17349707 -5.1.3.8 * homo sapiens 35.8 35.8 1 PMID:9990133 -5.1.3.8 * sus scrofa 32.0 5.3 5 PMID:14285488;PMID:17349707;PMID:19707758 -5.1.3.8 * trichormus variabilis 131.0 86.6 6 PMID:23850800 -5.1.3.9 * enterobacter cloacae 478.0 478.0 1 * -5.1.99.1 * metallosphaera sedula 218.0 218.0 2 PMID:22752162 -5.1.99.1 * ovis aries 0.35 0.35 1 PMID:13934211 -5.1.99.1 * rattus norvegicus 8400.0 8400.0 1 PMID:2862845;PMID:3071715 -5.1.99.4 * homo sapiens 77.5 72.95 2 PMID:19156321 -5.1.99.5 * microbacterium maritypicum 100.0 89.5 2 PMID:15784981 -5.1.99.5 * pseudomonas sp. 20.8 20.8 1 PMID:1459947 -5.1.99.7 * escherichia coli 505.0 256.34 2 PMID:9182560;PMID:9651328 -5.1.99.8 * escherichia coli 11.0 8.4 2 PMID:9006053;PMID:9651328 -5.2.1.1 * pseudomonas fluorescens 24.4 24.4 1 PMID:5780844 -5.2.1.1 * serratia marcescens 20.0 20.0 1 PMID:10945267 -5.2.1.4 * corynebacterium glutamicum 8700.0 540.0 3 PMID:16000747 -5.2.1.5 * butyrivibrio hungatei 0.00047 0.00047 1 PMID:17007428 -5.2.1.5 * clostridium sporogenes 0.4 0.4 1 * -5.2.1.5 * lactobacillus delbrueckii subsp. bulgaricus 353.5 178.65 2 PMID:21340675 -5.2.1.5 * pseudobutyrivibrio ruminis 0.00076 0.00046 2 PMID:17007428 -5.2.1.5 * pseudobutyrivibrio xylanivorans 0.00059 0.00059 1 PMID:17007428 -5.2.1.8 * schistosoma mansoni 132.9 132.9 1 PMID:9535701 -5.2.1.8 * vibrio anguillarum 25.8 17.1 3 PMID:24931498 -5.3.1.1 * chlamydomonas reinhardtii 7193.0 7193.0 1 PMID:24157611 -5.3.1.1 * equus caballus 3183.0 3183.0 1 PMID:1168838 -5.3.1.1 * giardia duodenalis 3800.0 3800.0 1 PMID:15146481 -5.3.1.1 * homo sapiens 10240.0 6900.0 5 PMID:1128275;PMID:1168838;PMID:507849;PMID:5169140 -5.3.1.1 * leishmania donovani 8.76 4.885 2 PMID:22342510 -5.3.1.1 * methanococcus maripaludis 0.044 0.044 1 PMID:8288525 -5.3.1.1 * mycobacterium tuberculosis 5700.0 5700.0 1 PMID:16978361 -5.3.1.1 * oryctolagus cuniculus 7800.0 7800.0 1 PMID:236473 -5.3.1.1 * plasmodium falciparum 679.0 679.0 1 PMID:26206206 -5.3.1.1 * saccharomyces cerevisiae 19250.0 14625.0 2 PMID:3056516 -5.3.1.1 * spinacia oleracea 400.0 400.0 1 PMID:7858230 -5.3.1.1 * staphylococcus aureus 13000.0 13000.0 1 PMID:19423633 -5.3.1.1 * trypanosoma brucei 2500.0 2500.0 1 PMID:8436128 -5.3.1.1 * trypanosoma cruzi 3527.0 3527.0 1 PMID:9108237 -5.3.1.13 * acidipropionibacterium acidipropionici 5.4 5.4 1 * -5.3.1.13 * escherichia coli 246.0 29.55 3 PMID:12805358;PMID:16390329;PMID:20954237 -5.3.1.13 * pseudomonas aeruginosa 29.5 29.5 1 PMID:21337483 -5.3.1.14 * aeribacillus pallidus 77.2 6.33 5 PMID:17653540 -5.3.1.14 * bacillus subtilis 15.8 2.58 5 PMID:31797048 -5.3.1.14 * caldicellulosiruptor obsidiansis 277.6 35.8 8 PMID:28960307 -5.3.1.14 * caldicellulosiruptor saccharolyticus 379.0 196.9 2 PMID:21761877 -5.3.1.14 * escherichia coli 3.0 3.0 1 * -5.3.1.14 * lactiplantibacillus plantarum 31.8 31.8 1 * -5.3.1.14 * pseudomonas sp. 109.0 109.0 1 * -5.3.1.14 * stutzerimonas stutzeri 140.0 140.0 1 PMID:15184124 -5.3.1.14 * thermoanaerobacterium saccharolyticum 197.0 131.3 2 PMID:20822145 -5.3.1.14 * thermoclostridium stercorarium 520.0 11.0 8 PMID:29124517 -5.3.1.14 * thermotoga maritima 55.0 6.7 11 PMID:20809285 -5.3.1.15 * bacillus licheniformis 54.0 24.0 3 PMID:21421786;PMID:29392387 -5.3.1.15 * bacillus velezensis 2.2 0.65 3 PMID:31529161 -5.3.1.15 * caldanaerobius polysaccharolyticus 4.5 0.595 4 PMID:32527523 -5.3.1.15 * cohnella laeviribosi 50.2 13.4 3 PMID:17189362;PMID:29392387 -5.3.1.15 * dictyoglomus turgidum 33.1 0.2055 12 PMID:22350292;PMID:29392387 -5.3.1.15 * escherichia coli 5.8 5.8 1 PMID:29392387 -5.3.1.15 * klebsiella aerogenes 7.7 7.7 1 * -5.3.1.15 * paenibacillus baekrokdamisoli 7.34 1.6600000000000001 6 * -5.3.1.15 * providencia stuartii 24.04 0.022 21 PMID:20541111;PMID:29392387 -5.3.1.15 * serratia proteamaculans 26.2 1.05 11 PMID:20695994;PMID:29392387 -5.3.1.15 * thermoflavimicrobium dichotomicum 10.4 5.15 4 * -5.3.1.15 * thermosediminibacter oceani 7.1 7.1 1 PMID:29392387 -5.3.1.16 * salmonella enterica subsp. enterica serovar typhimurium 7.8 7.8 1 * -5.3.1.17 * pseudomonas sp. 4.36 4.36 1 * -5.3.1.20 * mycolicibacterium smegmatis 1.84 1.84 1 PMID:240851 -5.3.1.22 * metabacillus fastidiosus 3125.0 3125.0 1 PMID:7448201 -5.3.1.23 * klebsiella pneumoniae 0.3 0.3 1 PMID:2838472 -5.3.1.24 * bacillus subtilis 5.15 5.15 1 PMID:110789 -5.3.1.24 * escherichia coli 98.7 53.74 2 PMID:3298981;PMID:7727400 -5.3.1.24 * geobacillus thermopakistaniensis 397.0 397.0 1 PMID:31669755 -5.3.1.24 * ogataea henricii 0.0071 0.0071 1 * -5.3.1.24 * saccharomyces cerevisiae 102.0 102.0 1 PMID:3286643 -5.3.1.24 * serratia marcescens 5.5 5.5 1 PMID:4559725 -5.3.1.24 * thermotoga maritima 14.3 14.3 1 PMID:11265469 -5.3.1.25 * caldanaerobius polysaccharolyticus 108.23 101.11500000000001 6 PMID:31778693;PMID:32061850;PMID:33296692 -5.3.1.25 * caldicellulosiruptor saccharolyticus 76.0 43.0 4 PMID:19856146;PMID:33296692 -5.3.1.25 * dictyoglomus turgidum 33.0 33.0 1 PMID:22627384 -5.3.1.25 * escherichia coli 63.7 63.5 2 PMID:4632320 -5.3.1.25 * halothermothrix orenii 151.1 128.65 2 * -5.3.1.25 * klebsiella aerogenes 6.0 6.0 1 PMID:236476 -5.3.1.25 * raoultella sp. 63.9 63.9 1 PMID:33296692 -5.3.1.25 * raoultella sp. kdh14 127.3 115.3 3 PMID:31827610 -5.3.1.25 * thermanaeromonas toyohensis 98.08 91.8 2 PMID:33296692 -5.3.1.26 * lactococcus lactis 1.79 1.79 1 PMID:17868944 -5.3.1.27 * bacillus methanolicus 5.5 5.5 1 PMID:30246938 -5.3.1.27 * bacillus subtilis 2.5 2.5 1 PMID:30246938 -5.3.1.27 * methylococcus capsulatus 1560.0 1560.0 1 PMID:4219834 -5.3.1.27 * mycobacterium gastri 563.0 154.0 3 PMID:17520247;PMID:30246938 -5.3.1.27 * uncultured bacterium 20.0 20.0 1 * -5.3.1.29 * thermococcus kodakarensis 32.3 30.799999999999997 2 PMID:17303759;PMID:22511789 -5.3.1.3 * caldicellulosiruptor saccharolyticus 62.0 15.0 3 PMID:19856146 -5.3.1.3 * escherichia coli 63.7 63.5 2 PMID:4632320 -5.3.1.3 * klebsiella aerogenes 36.5 1.9 13 PMID:17189171;PMID:236476 -5.3.1.3 * thermanaeromonas toyohensis 98.08 85.52 3 PMID:31615684 -5.3.1.32 * escherichia coli o55:h7 61.0 61.0 1 PMID:21454635 -5.3.1.34 * bos taurus 6570.0 3289.525 2 PMID:3987693 -5.3.1.4 * [clostridium] hylemonae 0.44 0.44 1 PMID:29684065 -5.3.1.4 * acinetobacter sp. 0.183 0.143 2 PMID:19151970 -5.3.1.4 * alicyclobacillus acidocaldarius 35.5 28.700000000000003 4 PMID:16332764 -5.3.1.4 * alicyclobacillus hesperidum 0.52 0.52 1 PMID:26335445 -5.3.1.4 * arthrobacter sp. 0.232 0.129 2 PMID:22917022 -5.3.1.4 * bacillus licheniformis 105.0 105.0 1 PMID:20048061 -5.3.1.4 * bacillus subtilis 262.0 262.0 1 PMID:19727704 -5.3.1.4 * bacillus velezensis 13.98 13.98 1 PMID:32617845 -5.3.1.4 * bifidobacterium adolescentis 24.47 24.47 1 PMID:32411693 -5.3.1.4 * enterococcus faecium 180.0 2.4 5 PMID:29211024;PMID:33502742 -5.3.1.4 * geobacillus kaustophilus 4.57 4.03 3 PMID:24419630 -5.3.1.4 * geobacillus stearothermophilus 185.0 4.505 19 PMID:15639234;PMID:16386851;PMID:16834609;PMID:17337581;PMID:22103589;PMID:30282606 -5.3.1.4 * geobacillus thermodenitrificans 4.82 0.5815 8 PMID:16084621;PMID:16489490 -5.3.1.4 * halalkalibacterium halodurans 33.2 25.3 5 PMID:15639234;PMID:16332764 -5.3.1.4 * heyndrickxia coagulans 8.0 4.55 2 PMID:27363468 -5.3.1.4 * klebsiella pneumoniae subsp. pneumoniae 1.8 1.8 1 * -5.3.1.4 * lactiplantibacillus plantarum 263.4 253.0 3 PMID:13539034;PMID:18031349 -5.3.1.4 * lactobacillus gayonii 5.31 5.31 1 PMID:236475 -5.3.1.4 * lentilactobacillus parabuchneri 15.52 15.52 1 * -5.3.1.4 * levilactobacillus brevis 8.33 8.33 1 PMID:30251190 -5.3.1.4 * limosilactobacillus fermentum 11.0 11.0 1 PMID:24220791 -5.3.1.4 * pseudoalteromonas haloplanktis 5.2 5.2 1 PMID:27586234 -5.3.1.4 * thermoanaerobacter mathranii 4.0 2.0275 2 PMID:15168095 -5.3.1.4 * thermotoga maritima 7.8 4.0 3 PMID:15168095;PMID:22103589 -5.3.1.5 * arthrobacter sp. 12.5 12.5 1 PMID:1854338 -5.3.1.5 * bacillus sp. (in: firmicutes) 16.4 11.69 3 PMID:16349464 -5.3.1.5 * bifidobacterium adolescentis 3.17 3.17 1 PMID:7764860 -5.3.1.5 * ciona intestinalis 2.2 2.2 1 PMID:19204828 -5.3.1.5 * deamia testudo 204.0 204.0 1 * -5.3.1.5 * escherichia coli 1.69 0.151 29 PMID:16243589;PMID:16672486;PMID:16878542;PMID:17308178;PMID:17662053;PMID:18586973 -5.3.1.5 * geobacillus stearothermophilus 2.7 2.7 1 * -5.3.1.5 * glutamicibacter nicotianae 1.63 0.73 3 PMID:16878542 -5.3.1.5 * lachnoclostridium phytofermentans 0.0344 0.021 2 PMID:19218403 -5.3.1.5 * lactococcus lactis subsp. lactis 4.39 4.39 1 * -5.3.1.5 * levilactobacillus brevis 6.4 6.4 1 PMID:236477 -5.3.1.5 * limosilactobacillus reuteri 0.57 0.57 1 PMID:24443973 -5.3.1.5 * opuntia ficus-indica 266.4 136.58999999999997 2 PMID:21253889 -5.3.1.5 * opuntia vulgaris 266.4 136.58999999999997 2 PMID:21253889 -5.3.1.5 * paraburkholderia sacchari 1.46 1.46 1 PMID:19898542 -5.3.1.5 * pectobacterium atrosepticum 0.81 0.71 3 PMID:16878542 -5.3.1.5 * piromyces sp. 1.1 0.96 4 PMID:17280608;PMID:17846724 -5.3.1.5 * saccharomyces cerevisiae 0.017 0.008 3 PMID:15806613 -5.3.1.5 * scheffersomyces stipitis 0.6 0.6 1 * -5.3.1.5 * streptomyces coelicolor 0.015 0.014499999999999999 2 PMID:16243589 -5.3.1.5 * streptomyces corchorusii 40.9 40.9 1 * -5.3.1.5 * streptomyces flavogriseus 20.2 20.2 1 PMID:16345476 -5.3.1.5 * streptomyces olivochromogenes 2.4 2.4 1 * -5.3.1.5 * streptomyces sp. 16.0 6.4 3 PMID:1724596;PMID:236477 -5.3.1.5 * thermoanaerobacter ethanolicus 17.0 10.0 2 PMID:21072563 -5.3.1.5 * thermoanaerobacterium saccharolyticum 4.18 4.18 1 PMID:8830690 -5.3.1.5 * thermus thermophilus 380.0 132.0 5 PMID:17846724;PMID:22586153 -5.3.1.6 * [bacillus] caldolyticus 52.7 52.7 1 PMID:7144591;PMID:956158 -5.3.1.6 * acetivibrio thermocellus 25690.0 1352.0 22 PMID:18984017;PMID:21132286 -5.3.1.6 * brucella anthropi 16.7 11.35 2 PMID:29913551;PMID:34116752 -5.3.1.6 * cyberlindnera jadinii 356.0 356.0 1 PMID:4773875 -5.3.1.6 * lathyrus oleraceus 1700.0 1700.0 1 PMID:16668459 -5.3.1.6 * pseudothermotoga lettingae 0.2 0.2 1 PMID:23386225 -5.3.1.6 * streptococcus pneumoniae 0.388 0.00745 14 * -5.3.1.6 * thermotoga maritima 290.0 238.5 2 PMID:22333529 -5.3.1.6 * thiobacillus thioparus 544.0 544.0 1 PMID:7144591;PMID:956158 -5.3.1.7 * agrobacterium tumefaciens 231.0 231.0 1 PMID:11330684 -5.3.1.7 * caballeronia jiangsuensis 621.2 275.6 3 * -5.3.1.7 * deltaproteobacteria bacterium 764.1 322.3 3 * -5.3.1.7 * gluconobacter thailandicus 10.4 10.4 1 PMID:35700128 -5.3.1.7 * mycolicibacterium smegmatis 2.25 2.25 1 PMID:5438047 -5.3.1.7 * pseudomonas syringae 818.6 546.2 2 PMID:33484446 -5.3.1.7 * stenotrophomonas rhizophila 437.5 267.2 3 PMID:35048315 -5.3.1.7 * xanthomonas phaseoli 355.1 93.4 9 PMID:36121717 -5.3.1.8 * alcaligenes sp. 0.313 0.306 3 PMID:19838696 -5.3.1.8 * amorphophallus konjac 5.95 5.95 1 * -5.3.1.8 * bacillus amyloliquefaciens 81.0 81.0 1 PMID:26171785 -5.3.1.8 * bacillus subtilis 0.0918 0.0225 5 PMID:19447949 -5.3.1.8 * candida albicans 380.0 380.0 1 PMID:7702743 -5.3.1.8 * geobacillus thermodenitrificans 890.0 890.0 1 PMID:19390787 -5.3.1.8 * homo sapiens 75.0 75.0 1 PMID:7702743 -5.3.1.8 * saccharomyces cerevisiae 420.0 420.0 1 PMID:7702743 -5.3.1.8 * sus scrofa 80.0 80.0 1 PMID:7702743 -5.3.1.8 * thermus thermophilus 1619.0 69.0 24 PMID:21115698;PMID:21729734 -5.3.1.8 * xanthomonas campestris 33.5 33.5 1 PMID:9450661 -5.3.1.9 * archaeoglobus fulgidus 0.06 0.06 1 PMID:11702074 -5.3.1.9 * carassius auratus 140.0 140.0 1 PMID:19472999 -5.3.1.9 * escherichia coli 212.6 212.6 1 * -5.3.1.9 * homo sapiens 870.0 610.0 4 PMID:19064002;PMID:5135316 -5.3.1.9 * lathyrus oleraceus 1470.0 1470.0 1 PMID:236464 -5.3.1.9 * methanococcus maripaludis 0.009 0.009 1 PMID:8288525 -5.3.1.9 * mus musculus 520.0 520.0 1 PMID:4722497 -5.3.1.9 * mycobacterium tuberculosis 617.7 617.7 1 PMID:16212940 -5.3.1.9 * pyrococcus furiosus 620.0 14.5 9 PMID:11344151;PMID:11533028;PMID:15465052;PMID:19159927 -5.3.1.9 * spinacia oleracea 690.0 690.0 1 PMID:16662282 -5.3.1.9 * thermococcus kodakarensis 43.0 43.0 1 * -5.3.1.9 * thermococcus litoralis 47.3 47.3 1 PMID:12560104 -5.3.1.9 * triticum aestivum 756.0 422.0 2 PMID:33774822 -5.3.1.9 * trypanosoma brucei brucei 48.5 48.5 1 PMID:18561188 -5.3.2.1 * sus scrofa 2.3 2.3 1 PMID:5824560 -5.3.2.2 * sus scrofa 5.06 5.06 1 PMID:5781999 -5.3.2.7 * anthracobia melaloma 3873.0 3873.0 1 PMID:15110094 -5.3.3.1 * bos taurus 3.5 3.5 1 PMID:1562558 -5.3.3.1 * comamonas testosteroni 30600.0 30600.0 1 PMID:16572455 -5.3.3.1 * homo sapiens 0.622 0.622 1 PMID:11463578 -5.3.3.10 * escherichia coli 148.3 128.15 2 PMID:2194841;PMID:7026235 -5.3.3.10 * pseudomonas putida 122.1 122.1 1 * -5.3.3.13 * ptilota filicina 1.06 1.06 1 PMID:7803384 -5.3.3.14 * streptococcus pneumoniae 8.7e-05 8.7e-05 1 PMID:12237320 -5.3.3.2 * bacillus subtilis 0.63 0.21000000000000002 6 PMID:15206931 -5.3.3.2 * cinchona robusta 0.046 0.046 1 PMID:9363768 -5.3.3.2 * claviceps purpurea 200.0 101.8 2 PMID:3207678;PMID:4021823 -5.3.3.2 * claviceps sp. 3000.0 3000.0 1 PMID:3740842 -5.3.3.2 * gallus gallus 73.0 73.0 1 PMID:4021823 -5.3.3.2 * homo sapiens 1.2 1.2 1 PMID:17202134 -5.3.3.2 * saccharomyces cerevisiae 0.109 0.109 1 PMID:13792054 -5.3.3.2 * sus scrofa 5.92 5.92 1 PMID:202196 -5.3.3.2 * synechocystis sp. 52.0 52.0 1 PMID:15547291 -5.3.3.21 * rattus norvegicus 960.0 480.03 2 PMID:11278886;PMID:9417087 -5.3.3.3 * bos taurus 32.0 32.0 1 PMID:13741692 -5.3.3.3 * escherichia coli 7.5 5.05 2 PMID:6402028 -5.3.3.3 * pseudomonas fragi 9.8 9.8 1 PMID:2361950 -5.3.3.4 * acinetobacter calcoaceticus 750.0 750.0 1 PMID:4215816 -5.3.3.4 * cupriavidus necator 23.09 23.09 1 PMID:9211711 -5.3.3.4 * pseudomonas putida 856.0 781.5 2 PMID:4199894;PMID:5330966 -5.3.3.4 * rhodococcus sp. (in: high g+c gram-positive bacteria) 860.0 860.0 1 PMID:16156722 -5.3.3.5 * homo sapiens 0.243 0.243 1 PMID:12133002 -5.3.3.7 * pseudomonas putida 116.0 116.0 1 PMID:5114987 -5.3.3.7 * pseudomonas sp. wu-0701 1267.0 1.2349999999999999 14 PMID:26293748;PMID:32994133 -5.3.3.7 * zea mays 3.68 1.8800000000000001 2 PMID:33360493 -5.3.3.8 * homo sapiens 21.0 21.0 1 PMID:15351645 -5.3.3.8 * rattus norvegicus 201.0 46.9 3 PMID:12356468;PMID:738702;PMID:8407371 -5.3.3.8 * saccharomyces cerevisiae 16.0 4.4 3 PMID:26527136;PMID:9837886 -5.3.3.9 * oryctolagus cuniculus 0.139 0.136 2 PMID:1137404;PMID:4420472 -5.3.4.1 * triticum aestivum 0.736 0.287 5 PMID:25849633 -5.3.99.12 * petiveria alliacea 0.012 0.012 1 PMID:19692535 -5.3.99.2 * bos taurus 4.5 4.5 1 PMID:9510973 -5.3.99.2 * danio rerio 14.9 14.9 1 PMID:16616995 -5.3.99.2 * gallus gallus 11.7 11.7 1 PMID:16616995 -5.3.99.2 * homo sapiens 1.89 1.4449999999999998 2 PMID:8093029;PMID:9475419 -5.3.99.2 * mus musculus 434.0 224.45 2 PMID:16616995 -5.3.99.2 * rattus norvegicus 30.0 1.7 3 PMID:10871602;PMID:109431;PMID:7132774 -5.3.99.3 * ascaridia galli 2.0 2.0 1 PMID:8546687 -5.3.99.3 * bos taurus 1.8 1.7000000000000002 2 PMID:838703 -5.3.99.3 * homo sapiens 510.0 2.4050000000000002 10 PMID:12460774;PMID:12672824;PMID:16399384;PMID:20605783 -5.3.99.3 * rattus norvegicus 2.5 2.1 4 PMID:15040786;PMID:20605783 -5.3.99.4 * bos taurus 2.0 0.5555 4 PMID:6338016;PMID:6752643;PMID:8051072;PMID:8280118 -5.3.99.4 * homo sapiens 46.0 5.699999999999999 6 PMID:15115769;PMID:16406803 -5.3.99.5 * homo sapiens 24.1 1.15 5 PMID:2195994;PMID:2999104;PMID:3707514;PMID:6221511;PMID:9873013 -5.3.99.5 * sus scrofa 0.231 0.118075 2 PMID:3745158;PMID:7197552 -5.3.99.7 * corynebacterium sp. 58.7 58.7 1 * -5.3.99.7 * pseudomonas fluorescens 9.79 6.944999999999999 2 PMID:28472670 -5.3.99.7 * rhodococcus opacus 150.0 75.9 5 PMID:22504818;PMID:28472670 -5.3.99.7 * sphingopyxis fribergensis 89.7 60.95 2 PMID:28472670 -5.3.99.7 * xanthobacter sp. 6.035 6.035 1 PMID:16348047 -5.3.99.8 * capsicum annuum 0.0073 0.0073 1 PMID:7920703 -5.4.2.10 * escherichia coli 10.0 2.795 4 PMID:10231382;PMID:8550580 -5.4.2.10 * helicobacter pylori 0.95 0.95 1 PMID:9171391 -5.4.2.10 * pseudomonas aeruginosa 2.5 0.55 3 PMID:10913078 -5.4.2.10 * staphylococcus aureus 0.1 0.1 1 PMID:9286983 -5.4.2.11 * escherichia coli 124.0 124.0 1 PMID:166274 -5.4.2.11 * homo sapiens 515.0 0.685 6 PMID:10303;PMID:9365161 -5.4.2.11 * hyphomicrobium sp. 3.22 3.22 1 PMID:10346 -5.4.2.11 * oryctolagus cuniculus 440.0 440.0 1 PMID:3016004 -5.4.2.11 * pseudomonas sp. 20.03 20.03 1 PMID:10346 -5.4.2.11 * saccharomyces cerevisiae 1280.0 1280.0 1 PMID:182494 -5.4.2.11 * schizosaccharomyces pombe 218.0 214.0 2 PMID:8765231 -5.4.2.11 * streptomyces coelicolor 2880.0 2880.0 1 PMID:1530847 -5.4.2.11 * sus scrofa 210.0 210.0 1 PMID:6296621 -5.4.2.12 * archaeoglobus fulgidus 3.3 3.3 1 PMID:17576516 -5.4.2.12 * bacillus anthracis 37.0 37.0 1 PMID:17085493 -5.4.2.12 * bacillus subtilis 621.0 310.507 2 PMID:33963;PMID:9830105 -5.4.2.12 * brugia malayi 256.0 174.5 2 PMID:15234973 -5.4.2.12 * caenorhabditis elegans 72.0 56.0 2 PMID:15234973 -5.4.2.12 * clostridium perfringens 0.24 0.24 1 PMID:9830105 -5.4.2.12 * dirofilaria immitis 225.0 225.0 2 PMID:21324604 -5.4.2.12 * geobacillus stearothermophilus 1500.0 1000.0 2 PMID:10388626 -5.4.2.12 * leishmania mexicana 419.0 419.0 1 PMID:15096219 -5.4.2.12 * micrococcus luteus 0.49 0.49 1 PMID:9830105 -5.4.2.12 * planococcus citreus 1.0 1.0 1 PMID:9830105 -5.4.2.12 * ricinus communis 1200.0 622.5 3 PMID:3004361;PMID:8260624 -5.4.2.12 * sporosarcina ureae 0.003 0.003 1 PMID:9830105 -5.4.2.12 * staphylococcus saprophyticus 0.1 0.1 1 PMID:9830105 -5.4.2.12 * streptomyces coelicolor 0.93 0.93 1 PMID:9830105 -5.4.2.12 * thermoplasma acidophilum 12.0 12.0 1 PMID:17576516 -5.4.2.12 * triticum aestivum 1027.0 1027.0 1 * -5.4.2.12 * trypanosoma brucei 100.4 100.4 1 PMID:10691985 -5.4.2.12 * wolbachia endosymbiont of dirofilaria immitis 71.0 71.0 1 PMID:21324604 -5.4.2.12 * wolbachia sp. 71.0 71.0 1 PMID:21324604 -5.4.2.12 * zea mays 202.5 202.5 1 PMID:2480892 -5.4.2.12 * zymomonas mobilis 2000.0 2000.0 1 PMID:3026343 -5.4.2.2 * bacillus subtilis 31.5 31.5 1 PMID:4212310 -5.4.2.2 * bos taurus 286.0 286.0 1 * -5.4.2.2 * fusarium oxysporum 5.3 3.2 2 PMID:22112903 -5.4.2.2 * giardia duodenalis 87.0 81.5 2 PMID:20507884 -5.4.2.2 * homo sapiens 1442.0 652.5 4 PMID:2149596;PMID:2533352 -5.4.2.2 * lathyrus oleraceus 156.9 156.9 1 * -5.4.2.2 * methanococcus maripaludis 0.01 0.01 1 PMID:8288525 -5.4.2.2 * mycobacterium tuberculosis 67.5 67.5 1 PMID:22809717 -5.4.2.2 * oryctolagus cuniculus 128.0 128.0 1 PMID:11035960 -5.4.2.2 * pseudomonas aeruginosa 28.0 19.7 2 PMID:8050998 -5.4.2.2 * saccharolobus solfataricus 0.0026 0.0026 1 PMID:15937189 -5.4.2.2 * saccharomyces cerevisiae 490.0 33.7 5 PMID:1100398;PMID:23103740;PMID:6216393 -5.4.2.2 * thermococcus kodakarensis 420.0 210.4 2 PMID:15342576 -5.4.2.2 * toxoplasma gondii 338.0 211.0 2 PMID:20153838 -5.4.2.2 * zea mays 11.7 5.765000000000001 4 PMID:9662542;PMID:9818085 -5.4.2.3 * sus scrofa 0.056 0.056 1 * -5.4.2.4 * gallus gallus 0.56 0.56 1 PMID:199431 -5.4.2.4 * homo sapiens 15.0 9.94 4 PMID:129153;PMID:163190;PMID:166276;PMID:9832630 -5.4.2.5 * mycolicibacterium smegmatis 114.0 114.0 1 PMID:14285271 -5.4.2.6 * euglena gracilis 4.463 4.463 1 PMID:4212162 -5.4.2.6 * lactobacillus delbrueckii subsp. lactis 113.0 113.0 1 * -5.4.2.6 * lactococcus lactis 113.0 40.0 3 PMID:11807265 -5.4.2.6 * levilactobacillus brevis 56.0 56.0 1 PMID:6230052 -5.4.2.6 * pyrococcus sp. 46.81 25.16 4 PMID:24391053 -5.4.2.7 * escherichia coli 142.0 78.75 2 PMID:1089430;PMID:4992818 -5.4.2.7 * geobacillus stearothermophilus 41.7 41.7 1 PMID:9692190 -5.4.2.7 * saccharomyces cerevisiae 0.32 0.29 3 PMID:23103740 -5.4.2.7 * thermococcus kodakarensis 210.0 210.0 1 PMID:15205420 -5.4.2.7 * thermotoga maritima 57.8 35.9 2 PMID:26924489 -5.4.2.8 * acinetobacter haemolyticus 1548.0 796.55 2 PMID:26640047 -5.4.2.8 * amorphophallus konjac 6.105 6.105 1 * -5.4.2.8 * giardia duodenalis 25.0 25.0 1 PMID:20507884 -5.4.2.8 * homo sapiens 49.0 49.0 1 * -5.4.2.8 * plasmodium falciparum 7.67 0.56 3 PMID:34973333 -5.4.2.8 * saccharolobus solfataricus 0.0025 0.0025 1 PMID:15937189 -5.4.2.8 * saccharomyces cerevisiae 0.9 0.9 1 * -5.4.2.8 * salmonella enterica 0.26 0.26 1 PMID:8922954 -5.4.2.9 * streptomyces hygroscopicus 15.5 15.5 1 PMID:2708146 -5.4.2.9 * tetrahymena pyriformis 113.0 113.0 1 PMID:1547241 -5.4.2.9 * trypanosoma cruzi 54.0 54.0 1 PMID:12672809 -5.4.3.2 * bacillus subtilis 0.62 0.62 1 PMID:10839984 -5.4.3.2 * clostridium sp. 6.4 5.25 2 PMID:5438361 -5.4.3.2 * clostridium subterminale 88.0 64.0 3 PMID:17042481 -5.4.3.2 * methanococcus maripaludis 1.1 0.5500090000000001 2 PMID:35544775 -5.4.3.2 * porphyromonas gingivalis 30.0 30.0 1 PMID:16957271 -5.4.3.3 * acetoanaerobium sticklandii 19.5 8.95 3 PMID:10617592;PMID:4540127;PMID:5480154 -5.4.3.3 * porphyromonas gingivalis 8.31 8.31 1 PMID:12093296 -5.4.3.5 * acetoanaerobium sticklandii 4.38 4.38 1 PMID:4711468 -5.4.3.6 * brevibacillus brevis 0.00188 0.00188 1 PMID:5021987 -5.4.3.8 * brassica napus 0.015 0.015 1 PMID:12767809 -5.4.3.8 * chlamydomonas reinhardtii 0.2 0.2 1 PMID:1985889 -5.4.3.8 * hordeum vulgare 0.384 0.384 1 PMID:16669079 -5.4.3.8 * lathyrus oleraceus 1.4 1.4 1 PMID:2037071 -5.4.3.8 * synechococcus sp. 0.0123 0.006195 2 PMID:1910318;PMID:19786580 -5.4.4.1 * ectopseudomonas oleovorans 38.0 38.0 1 PMID:10672020 -5.4.4.2 * arabidopsis thaliana 0.241 0.241 1 PMID:17190832 -5.4.4.2 * escherichia coli 0.808 0.808 1 PMID:9150206 -5.4.4.2 * pseudomonas aeruginosa 0.0017 0.0017 1 PMID:12624097 -5.4.4.3 * cupriavidus necator 4.7 4.7 1 PMID:10049374 -5.4.4.5 * aspergillus nidulans 3.2 3.2 1 PMID:19286665 -5.4.4.6 * colletotrichum gloeosporioides 0.87 0.615 4 PMID:26577673 -5.4.4.8 * thauera linaloolentis 57.0 57.0 1 PMID:26979141 -5.4.4.9 * pelobacter acidigallici 4.6 0.89 3 PMID:11807272;PMID:2298693 -5.4.4.9 * pelobacter massiliensis 0.4 0.34 3 PMID:16348719 -5.4.99.1 * clostridium tetanomorphum 7.5 7.5 1 * -5.4.99.11 * azotobacter vinelandii 2.9 0.97 7 PMID:28042032 -5.4.99.11 * bemisia argentifolia 181.0 181.0 1 * -5.4.99.11 * erwinia rhapontici 427.1 210.0 7 PMID:21229265;PMID:24866943;PMID:6743261 -5.4.99.11 * erwinia sp. 38.75 20.455 2 * -5.4.99.11 * erwinia sp. d12 19.8 19.8 1 PMID:24866943 -5.4.99.11 * erwinia sp. ejp617 718.2 69.84 5 PMID:34519920;PMID:35348852 -5.4.99.11 * klebsiella pneumoniae 2362.0 2362.0 3 PMID:24866943 -5.4.99.11 * klebsiella sp. lx3 328.0 328.0 1 PMID:24866943 -5.4.99.11 * pantoea dispersa 591.5 562.0 4 PMID:15746363;PMID:24866943;PMID:30290260 -5.4.99.11 * paraburkholderia acidicola 900.0 900.0 3 PMID:16508103;PMID:24866943 -5.4.99.11 * raoultella planticola 351.0 351.0 3 PMID:15746363;PMID:24866943 -5.4.99.11 * serratia plymuthica 957.5 310.0 6 PMID:16511267;PMID:22124943;PMID:24866943;PMID:26886729 -5.4.99.13 * cupriavidus metallidurans 0.18 0.18 1 PMID:26134562 -5.4.99.13 * geobacillus kaustophilus 0.75 0.75 1 PMID:19864421 -5.4.99.13 * nocardia farcinica 1.1 1.1 1 PMID:19864421 -5.4.99.13 * paraburkholderia xenovorans 0.34 0.34 1 PMID:19864421 -5.4.99.13 * streptomyces virginiae 3.3 1.0 3 PMID:10531377;PMID:9497386 -5.4.99.14 * cupriavidus necator 45.2 45.2 1 PMID:2241929 -5.4.99.14 * pseudomonas reinekei 57.3 43.05 2 PMID:19801657 -5.4.99.14 * rhodococcus rhodochrous 785.0 785.0 1 PMID:2818569 -5.4.99.15 * arthrobacter ramosus 145.2 145.2 1 * -5.4.99.15 * arthrobacter sp. 203.0 203.0 1 PMID:8611744 -5.4.99.15 * saccharolobus shibatae 550.0 550.0 1 PMID:9827330 -5.4.99.15 * saccharolobus solfataricus 192.0 19.0 3 PMID:15150700;PMID:18594890;PMID:8901122 -5.4.99.15 * sulfolobus acidocaldarius 116.5 106.5 3 PMID:9063973 -5.4.99.16 * acidiplasma sp. mba-1 3.57 3.57 1 * -5.4.99.16 * deinococcus geothermalis 14.95 14.95 1 * -5.4.99.16 * deinococcus radiodurans 11.4 11.4 1 PMID:29460000 -5.4.99.16 * enterobacter hormaechei 18.5 18.5 2 PMID:19523196;PMID:29460000 -5.4.99.16 * myxococcus sp. v11 172.7 172.7 1 PMID:33675938 -5.4.99.16 * picrophilus oshimae 80.0 2.195 10 PMID:16968068;PMID:29460000 -5.4.99.16 * pseudarthrobacter chlorophenolicus 6.3 6.3 1 PMID:30218299 -5.4.99.16 * pseudomonas monteilii 90.6 90.6 1 PMID:34409951 -5.4.99.16 * pseudomonas sp. 41.2 41.2 1 * -5.4.99.16 * stutzerimonas stutzeri 79.2 79.2 1 PMID:29460000 -5.4.99.16 * thermus aquaticus 135.0 75.9 2 * -5.4.99.16 * thermus thermophilus 2.0 2.0 1 PMID:29460000 -5.4.99.16 * uncultured bacterium 133.5 133.5 1 PMID:24146994 -5.4.99.17 * alicyclobacillus acidocaldarius 0.345 0.345 1 PMID:2253626 -5.4.99.17 * rhodopseudomonas palustris 0.1487 0.1487 1 PMID:8305486 -5.4.99.17 * zymomonas mobilis 2.27e-06 2.27e-06 1 * -5.4.99.18 * acetobacter aceti 36.0 36.0 1 PMID:16819818 -5.4.99.2 * cricetulus sp. 0.0002 0.000126 2 PMID:15647267 -5.4.99.2 * euglena gracilis 21.0 10.53 2 PMID:20379701 -5.4.99.2 * homo sapiens 67.4 14.0 3 PMID:2907367;PMID:6124211;PMID:7989334 -5.4.99.2 * metallosphaera sedula 2.2 2.2 1 PMID:22752162 -5.4.99.2 * methylorubrum extorquens 1.4 1.4 1 PMID:14734568 -5.4.99.2 * propionibacterium freudenreichii subsp. shermanii 26.0 26.0 1 PMID:10563814 -5.4.99.2 * pyrococcus horikoshii 0.0021 0.0021 1 PMID:25516375 -5.4.99.2 * saccharopolyspora erythraea 0.47 0.47 1 PMID:6143534 -5.4.99.2 * sinorhizobium meliloti 10.85 10.85 1 PMID:12844209 -5.4.99.30 * oryza sativa 35.2 35.2 2 PMID:17182701 -5.4.99.33 * siraitia grosvenorii 0.01024 0.009260000000000001 2 PMID:30754652 -5.4.99.39 * euphorbia tirucalli 0.352 0.352 1 PMID:23294602 -5.4.99.4 * eubacterium barkeri 0.51 0.51 1 * -5.4.99.40 * eriobotrya japonica 0.0032 0.0032 1 PMID:30216049 -5.4.99.40 * malus domestica 0.0293 0.0293 1 PMID:30216049 -5.4.99.5 * aspergillus nidulans 88500.0 32500.0 3 PMID:10428795 -5.4.99.5 * bacillus subtilis 210.0 205.0 2 PMID:2105742 -5.4.99.5 * chlamydomonas reinhardtii 0.198 0.198 1 PMID:1122289 -5.4.99.5 * cupriavidus necator 36.63 36.63 1 PMID:1262315 -5.4.99.5 * escherichia coli 52.0 52.0 1 PMID:795664 -5.4.99.5 * kitasatospora aureofaciens 300.0 210.5 2 PMID:3037265;PMID:4211872 -5.4.99.5 * mycobacterium tuberculosis 74.0 37.6 2 PMID:15737998 -5.4.99.5 * ogataea angusta 168.0 168.0 1 PMID:10894726 -5.4.99.5 * saccharomyces cerevisiae 40200.0 4800.0 3 PMID:10428795 -5.4.99.5 * solanum tuberosum 21.7 21.7 1 PMID:3341760 -5.4.99.5 * thermus thermophilus 25.0 25.0 1 PMID:14727008 -5.4.99.5 * xanthomonas oryzae 48.6 24.52 2 PMID:20128700 -5.4.99.63 * cereibacter sphaeroides 0.05 0.05 1 PMID:18819910 -5.4.99.7 * bos taurus 1.747 1.747 1 PMID:14678783 -5.4.99.7 * rattus norvegicus 4.6e-05 4.4449999999999996e-05 2 PMID:16440058 -5.4.99.7 * saccharomyces cerevisiae 0.0014 2.92e-05 3 PMID:16235265;PMID:1731628 -5.4.99.7 * sus scrofa 0.0043 0.0043 1 PMID:3355560 -5.4.99.8 * poterioochromonas malhamensis 0.00019 0.00019 1 PMID:11946114 -5.5.1.1 * arthrobacter sp. 41.0 41.0 1 PMID:14769475 -5.5.1.1 * cutaneotrichosporon cutaneum 18.2 18.2 1 PMID:8110801 -5.5.1.1 * delftia acidovorans 0.115 0.115 1 * -5.5.1.1 * pseudomonas aeruginosa 0.035 0.026000000000000002 2 PMID:18331335 -5.5.1.1 * pseudomonas putida 187.0 90.0 3 PMID:2280697;PMID:4199894;PMID:4449126 -5.5.1.1 * rhodococcus opacus 8.3 4.3950000000000005 2 * -5.5.1.10 * nocardia sp. 312.0 312.0 1 PMID:3667522 -5.5.1.10 * pseudomonas rhodesiae 120.0 82.5 2 * -5.5.1.11 * cupriavidus necator 80.4 0.24 3 PMID:2327971;PMID:8215795 -5.5.1.12 * abies grandis 0.0214 0.0214 1 PMID:8053674 -5.5.1.19 * paracoccus haeundaensis 0.356 0.356 1 PMID:23412054 -5.5.1.2 * agrobacterium tumefaciens 0.5 0.5 1 PMID:17074892 -5.5.1.2 * pseudomonas putida 800.0 800.0 1 PMID:4199895 -5.5.1.20 * alternaria solani 1.69 1.69 1 PMID:18256508 -5.5.1.23 * streptomyces peucetius 14.3 14.3 1 PMID:10200167 -5.5.1.3 * alcaligenes faecalis 0.433 0.433 1 PMID:14247682 -5.5.1.4 * archaeoglobus fulgidus 11.8 11.8 1 PMID:11015222 -5.5.1.4 * methanothermobacter thermautotrophicus 0.0003 0.0003 1 PMID:19740749 -5.5.1.4 * rattus norvegicus 0.26 0.238 2 PMID:3600356;PMID:6773943 -5.5.1.4 * saccharomyces cerevisiae 0.22 0.086 5 PMID:19060162;PMID:2205246 -5.5.1.4 * synechocystis sp. 0.02 0.0165 4 PMID:14730448 -5.5.1.5 * aspergillus niger 284.0 284.0 1 PMID:4448182 -5.5.1.5 * neurospora crassa 600.0 485.0 2 PMID:8132467 -5.5.1.6 * eubacterium ramulus 914.0 914.0 1 PMID:15127184 -5.5.1.6 * glycine max 340.0 340.0 1 PMID:3384815 -5.5.1.6 * soja hispida 0.2 0.2 1 * -5.5.1.7 * delftia acidovorans 0.058 0.058 1 * -5.5.1.7 * pseudomonas sp. 2.8 2.8 1 PMID:3360749 -5.5.1.7 * rhodococcus opacus 18.0 18.0 1 PMID:11405892 -5.6.1.1 * caenorhabditis elegans 0.07 0.07 1 PMID:19619244 -5.6.1.1 * homo sapiens 1.46 4.6e-05 3 PMID:16219033;PMID:34121983 -5.6.1.10 * bos taurus 2.6e-06 2.6e-06 1 PMID:1356434 -5.6.1.10 * entamoeba histolytica 0.412 0.412 1 PMID:24486610 -5.6.1.10 * homo sapiens 0.025 0.00283 5 PMID:23940031;PMID:25615450 -5.6.1.2 * asterias 0.8 0.8 1 * -5.6.1.2 * bos taurus 1.2 0.11 7 PMID:2950853 -5.6.1.2 * chlamydomonas reinhardtii 2.3 2.3 1 PMID:6237107 -5.6.1.2 * colobocentrotus sp. 2.8 2.8 1 * -5.6.1.2 * gallus gallus 0.01 0.01 1 PMID:1979531 -5.6.1.2 * heliocidaris crassispina 1.1 0.6100000000000001 2 PMID:1825599 -5.6.1.2 * hemicentrotus pulcherrimus 2.23 0.9500000000000001 4 PMID:1825599;PMID:2950296;PMID:6215400 -5.6.1.2 * homo sapiens 0.026 0.014 11 PMID:19957446;PMID:7989508 -5.6.1.2 * mytilus edulis 0.72 0.62 3 PMID:1487508 -5.6.1.2 * pseudocentrotus depressus 0.08 0.065 2 PMID:2959658 -5.6.1.2 * rattus norvegicus 0.48 0.33 3 PMID:7876216 -5.6.1.2 * strongylocentrotus droebachiensis 0.2 0.2 1 PMID:2950295 -5.6.1.2 * strongylocentrotus purpuratus 0.2 0.2 1 PMID:2950295 -5.6.1.2 * tetrahymena pyriformis 2.5 0.68 6 PMID:158011;PMID:20950 -5.6.1.2 * tetrahymena thermophila 0.3 0.156 2 PMID:22569523;PMID:2950293 -5.6.1.2 * tripneustes gratilla 0.26 0.26 1 * -5.6.1.3 * dictyostelium discoideum 11.67 11.67 1 PMID:10545495 -5.6.1.5 * saccharomyces cerevisiae 0.88 0.505 2 PMID:15135049 -5.6.1.6 * homo sapiens 0.06 0.06 1 PMID:15247233 -5.6.1.7 * allochromatium vinosum 0.059 0.059 1 PMID:1349470 -5.6.1.7 * amoeba proteus 0.053 0.053 1 PMID:11722184 -5.6.1.7 * bos taurus 0.0193 0.0193 1 PMID:7601114 -5.6.1.7 * cereibacter sphaeroides 0.134 0.134 1 PMID:1678280 -5.6.1.7 * escherichia coli 0.751 0.751 1 PMID:1678280 -5.6.1.7 * pyrococcus furiosus 0.053 0.04 3 PMID:17440915 -5.6.1.7 * sulfolobus sp. 0.02 0.02 1 PMID:9464270 -5.6.1.7 * sulfurisphaera tokodaii 0.02 0.02 2 PMID:9245723 -5.6.1.7 * thermoanaerobacter brockii 0.04 0.04 1 PMID:7912671 -5.6.1.7 * thermococcus sp. 0.031 0.031 1 PMID:11741308 -5.6.1.7 * thermus thermophilus 0.1 0.1 1 PMID:1682319 -5.6.1.8 * acanthamoeba castellanii 4.0 0.8 5 PMID:6126796 -5.6.1.8 * bos taurus 0.15 0.007 11 PMID:2937178;PMID:31357;PMID:3160691 -5.6.1.8 * cavia porcellus 0.06 0.05 3 PMID:6446937 -5.6.1.8 * gallus gallus 0.07 0.01 3 PMID:8368268 -5.6.1.8 * meleagris gallopavo 0.58 0.58 1 PMID:2950927 -5.6.1.8 * oncorhynchus mykiss 0.09 0.0462 2 PMID:18515165;PMID:9262007 -5.6.1.8 * rattus norvegicus 0.82 0.35 25 PMID:10650719;PMID:17494635;PMID:18346177;PMID:6219669;PMID:6448166;PMID:9262007 -5.6.1.8 * trachemys scripta 0.04 0.02035 2 PMID:18515165;PMID:9262007 -5.6.1.9 * acidaminococcus fermentans 2000.0 2000.0 1 PMID:7607244 -5.6.2.1 * escherichia coli 31700.0 31700.0 1 PMID:21310243 -5.6.2.3 * tequatrovirus t4 162.0 81.1 2 PMID:6092351 -5.6.2.7 * escherichia coli 1e-08 1e-08 1 PMID:18165229 -5.99.1.4 * brevundimonas vesicularis 0.2 0.14 3 * -5.99.1.4 * comamonas testosteroni 55.4 0.23500000000000001 4 * -5.99.1.4 * pseudomonas sp. 62.0 62.0 1 PMID:9722670 -6.1.1.1 * geobacillus stearothermophilus 1.8 1.8 1 PMID:10572925 -6.1.1.1 * homo sapiens 7.6e-06 7.6e-06 1 PMID:12509991 -6.1.1.1 * rattus norvegicus 18.35 18.35 1 PMID:31184 -6.1.1.1 * saccharomyces cerevisiae 8.74 1.9849999999999999 4 PMID:3056726;PMID:328277 -6.1.1.10 * escherichia coli 66.7 66.7 1 PMID:4567120 -6.1.1.10 * lupinus sp. 0.0462 0.0462 1 * -6.1.1.10 * mycolicibacterium smegmatis 0.09 0.08499999999999999 2 PMID:971320 -6.1.1.10 * ovis aries 0.675 0.54 2 PMID:566665;PMID:566666 -6.1.1.10 * rattus norvegicus 0.11 0.077 2 PMID:1794973;PMID:921771 -6.1.1.10 * thermus thermophilus 1.4 1.4 1 PMID:3542990 -6.1.1.10 * triticum aestivum 0.087 0.087 1 PMID:1157945 -6.1.1.10 * vigna radiata var. radiata 0.161 0.161 1 PMID:16661668 -6.1.1.11 * bombyx mori 10.87 10.87 1 PMID:2826448 -6.1.1.11 * bos taurus 0.76 0.093 3 PMID:10764807;PMID:13783661;PMID:6565588 -6.1.1.11 * escherichia coli 2.7 2.7 1 PMID:4350948 -6.1.1.11 * geobacillus stearothermophilus 0.106 0.106 1 PMID:690138 -6.1.1.11 * lupinus luteus 0.15 0.15 1 PMID:240681 -6.1.1.11 * saccharomyces cerevisiae 2.53 1.2725 2 PMID:7686490 -6.1.1.12 * homo sapiens 17.0 7.300000000000001 8 PMID:17384640;PMID:17434317;PMID:8449960 -6.1.1.12 * rattus norvegicus 0.395 0.395 1 PMID:8910590 -6.1.1.12 * saccharomyces cerevisiae 9.0 4.9 2 PMID:6162464;PMID:6362667 -6.1.1.12 * thermococcus kodakarensis 0.11 0.11 2 PMID:7590306 -6.1.1.12 * thermus thermophilus 0.321 0.0441 10 PMID:10727213;PMID:9220965 -6.1.1.12 * vigna radiata var. radiata 0.326 0.326 1 * -6.1.1.13 * lactiplantibacillus plantarum 0.5 0.5 1 PMID:13795638 -6.1.1.14 * bombyx mori 1.65 1.65 1 PMID:4044548 -6.1.1.14 * escherichia coli 8.7 8.7 1 PMID:4594761 -6.1.1.14 * saccharomyces cerevisiae 0.55 0.2787 2 PMID:7008831 -6.1.1.14 * staphylococcus aureus 0.47 0.47 1 PMID:4295604 -6.1.1.14 * thermus thermophilus 0.124 0.124 1 PMID:9490048 -6.1.1.15 * delonix regia 1.655 0.878 2 * -6.1.1.15 * rattus norvegicus 2.45 0.9375 4 PMID:1517216;PMID:1530604;PMID:1794973 -6.1.1.16 * oryctolagus cuniculus 0.22 0.22 1 PMID:9810464 -6.1.1.16 * rattus norvegicus 6.25 3.29 3 PMID:990314 -6.1.1.17 * bacillus subtilis 0.16 0.112 2 PMID:3003506;PMID:9674110 -6.1.1.17 * caesalpinia bondue 0.0148 0.0148 1 * -6.1.1.17 * chlamydomonas reinhardtii 0.008 0.008 1 PMID:2303494 -6.1.1.17 * escherichia coli 1.95 1.1905000000000001 4 PMID:1384858;PMID:3003503;PMID:368055 -6.1.1.17 * hemerocallis fulva 0.0396 0.0396 1 * -6.1.1.17 * triticum aestivum 0.06 0.048 2 PMID:6617644 -6.1.1.17 * vigna radiata var. radiata 0.0263 0.0263 1 * -6.1.1.18 * escherichia coli 1.28 0.6937 2 PMID:3911010;PMID:6749844;PMID:6989402 -6.1.1.18 * homo sapiens 0.00079 0.00079 1 PMID:24656866 -6.1.1.19 * escherichia coli 4.984 4.984 1 PMID:37899 -6.1.1.19 * homo sapiens 0.286 0.286 1 PMID:16430231 -6.1.1.19 * mus musculus 0.000609 0.000609 1 PMID:8275012 -6.1.1.19 * mycolicibacterium smegmatis 0.00703 0.00703 1 PMID:3782054 -6.1.1.19 * rattus norvegicus 9.5 9.5 1 PMID:7076660 -6.1.1.2 * bos taurus 1.45 1.45 1 * -6.1.1.2 * homo sapiens 0.0018 0.0018 1 PMID:11676605 -6.1.1.2 * lupinus luteus 0.45 0.45 1 PMID:240681 -6.1.1.20 * chlorobium limicola 0.0107 0.0107 1 PMID:3081498 -6.1.1.20 * escherichia coli 19.8 19.8 1 PMID:6360212 -6.1.1.20 * gallus gallus 0.124 0.124 1 PMID:7103994 -6.1.1.20 * homo sapiens 0.19 0.19 1 PMID:12962494 -6.1.1.20 * methanosarcina barkeri 1.15 1.15 1 PMID:6373755 -6.1.1.20 * phaseolus vulgaris 0.11 0.11 1 PMID:3081498 -6.1.1.20 * saccharomyces cerevisiae 0.385 0.385 1 PMID:6992780 -6.1.1.20 * staphylococcus aureus 0.12 0.097 2 PMID:11281723 -6.1.1.20 * synechococcus elongatus pcc 7942 = fachb-805 0.092 0.092 1 PMID:3081498 -6.1.1.20 * thermus thermophilus 0.31 0.21 3 PMID:9675230 -6.1.1.21 * escherichia coli 121.8 121.8 1 PMID:4591623 -6.1.1.21 * oryctolagus cuniculus 0.687 0.687 1 PMID:246747 -6.1.1.21 * rattus norvegicus 0.618 0.618 1 PMID:6712685 -6.1.1.21 * salmonella enterica subsp. enterica serovar typhimurium 5.087 5.087 1 PMID:4985616 -6.1.1.22 * geobacillus stearothermophilus 0.113 0.113 1 PMID:690138 -6.1.1.22 * vicia faba 0.472 0.472 1 * -6.1.1.22 * vicia sativa 0.287 0.287 1 * -6.1.1.22 * vigna radiata var. radiata 0.566 0.566 1 * -6.1.1.23 * thermus thermophilus 32.1 32.1 1 PMID:10727213 -6.1.1.24 * bacillus subtilis 0.16 0.16 1 PMID:9674110 -6.1.1.3 * rattus norvegicus 0.7 0.5 2 PMID:7459319;PMID:8049265 -6.1.1.3 * saccharomyces pastorianus 0.636 0.636 1 PMID:670153 -6.1.1.3 * thermus thermophilus 0.353 0.353 1 PMID:8031907 -6.1.1.4 * aquifex aeolicus 1.17 0.235 3 PMID:12820878;PMID:15177296 -6.1.1.4 * cricetulus griseus 0.0068 0.0068 1 PMID:3971983 -6.1.1.4 * cyberlindnera jadinii 3.92 3.92 1 PMID:1100400 -6.1.1.4 * escherichia coli 2.8 1.5 8 PMID:10024478;PMID:10529176;PMID:10828991;PMID:11170439;PMID:12739900;PMID:12820878 -6.1.1.4 * euglena gracilis 1.34 1.2865000000000002 2 PMID:6794616 -6.1.1.4 * neurospora crassa 0.325 0.325 1 PMID:2942398 -6.1.1.4 * phaseolus vulgaris 1.55 1.245 2 PMID:6630191;PMID:7050099 -6.1.1.4 * saccharomyces cerevisiae 1.804 1.804 1 PMID:4567786 -6.1.1.5 * escherichia coli 0.97 0.51 2 PMID:4581276;PMID:793865 -6.1.1.5 * geobacillus stearothermophilus 254.5 254.5 1 PMID:4336851 -6.1.1.5 * ovis aries 0.06 0.06 1 PMID:4074679 -6.1.1.5 * rattus norvegicus 0.00084 0.00084 1 PMID:244419 -6.1.1.5 * thermus thermophilus 73.8 73.8 1 * -6.1.1.6 * escherichia coli 405.0 212.3 2 PMID:11946604;PMID:4333590 -6.1.1.6 * geobacillus stearothermophilus 1.79 1.0675 2 PMID:690138;PMID:8743569 -6.1.1.6 * homo sapiens 0.0133 0.00165 4 PMID:10952987 -6.1.1.6 * oryctolagus cuniculus 0.044 0.044 1 PMID:921771 -6.1.1.6 * rattus norvegicus 0.449 0.438 2 PMID:3365243;PMID:7372681 -6.1.1.7 * bombyx mori 2.65 2.65 1 PMID:6570482 -6.1.1.7 * escherichia coli 2.4 2.4 1 PMID:7005211 -6.1.1.7 * saccharomyces cerevisiae 0.2 0.184 2 PMID:7013809 -6.1.1.7 * streptococcus pneumoniae 0.011 0.0048 4 PMID:18842590 -6.1.1.7 * sus scrofa 0.114 0.07050000000000001 2 PMID:13783653 -6.1.1.7 * thermus thermophilus 0.105 0.105 1 PMID:12542696 -6.1.1.9 * escherichia coli 0.01 0.01 1 * -6.1.1.9 * euglena gracilis 0.38 0.38 1 PMID:6155123 -6.1.1.9 * geobacillus stearothermophilus 0.0045 0.0045 1 * -6.1.1.9 * mycolicibacterium smegmatis 0.0042 0.0042 1 PMID:109126 -6.1.1.9 * oryctolagus cuniculus 0.252 0.146 2 PMID:2556394;PMID:3609329 -6.1.1.9 * rattus norvegicus 0.722 0.722 1 PMID:3378054 -6.1.1.9 * saccharomyces cerevisiae 0.42 0.42 1 * -6.2.1.1 * acetobacter aceti 3.5 3.5 1 PMID:12800 -6.2.1.1 * bradyrhizobium japonicum 16.1 16.1 1 PMID:1970239 -6.2.1.1 * dunaliella tertiolecta 52.873 26.878999999999998 2 PMID:27025661 -6.2.1.1 * haloarcula marismortui 13.4 13.4 1 PMID:15947865 -6.2.1.1 * methanothrix soehngenii 48.3 48.3 1 PMID:2571608 -6.2.1.1 * methanothrix thermoacetophila 28.0 28.0 1 PMID:22927778 -6.2.1.1 * mus musculus 26.8 19.35 2 PMID:11150295 -6.2.1.1 * penicillium chrysogenum 24.0 24.0 1 PMID:1347531 -6.2.1.1 * saccharomyces cerevisiae 1.241 1.241 1 PMID:2884217 -6.2.1.11 * sus scrofa 0.89 0.89 1 PMID:14257635 -6.2.1.12 * arabidopsis thaliana 12.5 12.5 1 PMID:10664468 -6.2.1.12 * nicotiana tabacum 3.624 3.624 1 PMID:16900579 -6.2.1.12 * plagiochasma appendiculatum 0.1136 0.039349999999999996 4 PMID:25593011 -6.2.1.12 * populus trichocarpa x populus deltoides 0.33 0.13 3 PMID:9489021 -6.2.1.13 * archaeoglobus fulgidus 0.3 0.16499999999999998 2 PMID:11702074 -6.2.1.13 * giardia duodenalis 178.0 178.0 1 PMID:8557109 -6.2.1.13 * halococcus saccharolyticus 0.45 0.04 3 PMID:11409546 -6.2.1.13 * haloferax volcanii 0.1 0.1 1 PMID:11409546 -6.2.1.13 * halorubrum saccharovorum 0.1 0.1 1 PMID:11409546 -6.2.1.13 * pyrococcus furiosus 64.6 47.3 2 PMID:8830684 -6.2.1.14 * ectopseudomonas mendocina 77.3 77.3 1 * -6.2.1.14 * lysinibacillus sphaericus 1.0 1.0 1 PMID:1445232 -6.2.1.16 * rattus norvegicus 2.63 2.465 2 PMID:6539623 -6.2.1.16 * sinorhizobium meliloti 0.00424 0.00424 1 PMID:10735852 -6.2.1.16 * streptomyces lividans 4.91 4.91 1 PMID:25532451 -6.2.1.16 * zoogloea ramigera 52.2 52.2 1 PMID:7140777 -6.2.1.17 * bos taurus 3.36 1.8425 2 PMID:6122698;PMID:7341659 -6.2.1.17 * chloroflexus aurantiacus 2.5 2.5 1 PMID:11821399 -6.2.1.17 * metallosphaera sedula 18.0 0.091 3 PMID:18165310 -6.2.1.17 * salmonella enterica 22.0 9.325 4 PMID:11841231 -6.2.1.17 * salmonella enterica subsp. enterica serovar typhimurium 0.63 0.46499999999999997 2 * -6.2.1.17 * sulfurisphaera tokodaii 6.7 6.7 1 PMID:18165310 -6.2.1.18 * aquifex aeolicus 0.071 0.071 1 PMID:17227414 -6.2.1.18 * thermocrinis ruber 0.082 0.082 1 PMID:17227414 -6.2.1.2 * bos taurus 3.718 3.509 2 PMID:14253428;PMID:8869823 -6.2.1.2 * mus musculus 4.15 4.14 3 PMID:10362229;PMID:16378734 -6.2.1.2 * penicillium chrysogenum 0.02 0.02 1 PMID:18834333 -6.2.1.2 * pseudomonas aeruginosa 0.255 0.255 1 PMID:6800377 -6.2.1.20 * arabidopsis thaliana 0.0001572 0.0001027 3 PMID:26797881 -6.2.1.20 * escherichia coli 1.32 0.049499999999999995 4 PMID:10733890;PMID:2540190 -6.2.1.20 * vibrio harveyi 4.6 2.30000239 2 PMID:17179150;PMID:8384617 -6.2.1.25 * clarkia breweri 0.07 0.07 1 PMID:12054436 -6.2.1.25 * geobacter metallireducens 16.0 16.0 1 PMID:16313613 -6.2.1.25 * magnetospirillum sp. 13.4 6.7405 2 PMID:16553855 -6.2.1.25 * pseudomonas sp. 73.0 73.0 1 PMID:8335640 -6.2.1.25 * rhodopseudomonas palustris 25.0 25.0 1 PMID:3350788 -6.2.1.25 * thauera aromatica 16.5 16.5 1 PMID:12897012 -6.2.1.26 * escherichia coli 3.2 3.2 1 PMID:8955296 -6.2.1.26 * mycolicibacterium phlei 0.00084 0.00084 1 PMID:1663748 -6.2.1.27 * azoarcus sp. 4.8 4.8 1 PMID:18156265 -6.2.1.27 * geobacter metallireducens 0.012 0.0014 3 PMID:17449613 -6.2.1.27 * pseudomonas sp. 37.3 37.3 1 PMID:8477728 -6.2.1.27 * rhodopseudomonas palustris 0.0007 0.0007 1 PMID:2914844 -6.2.1.27 * thauera aromatica 4.12 4.12 1 PMID:11208796 -6.2.1.28 * rattus norvegicus 0.0015 0.0015 1 PMID:3183523 -6.2.1.3 * caulobacter vibrioides 0.00094 0.00094 1 PMID:21442318 -6.2.1.3 * escherichia coli 1.103 0.6715 2 PMID:3888279;PMID:7016858 -6.2.1.3 * geobacillus thermodenitrificans 8.7 5.75 2 PMID:22694860 -6.2.1.3 * mus musculus 0.723 0.723 1 PMID:15653672 -6.2.1.3 * oryctolagus cuniculus 1.19 1.19 1 PMID:12573249 -6.2.1.3 * rattus norvegicus 28.7 2.595 6 PMID:11266649;PMID:227853;PMID:467438;PMID:7278657;PMID:8663269 -6.2.1.3 * saccharomyces cerevisiae 0.145 0.133 2 PMID:17604220 -6.2.1.3 * yarrowia lipolytica 10.8 10.8 1 * -6.2.1.30 * aromatoleum evansii 0.48 0.240038 2 PMID:10629172 -6.2.1.30 * penicillium chrysogenum 0.199 0.02 3 PMID:18834333;PMID:21625874;PMID:6819990 -6.2.1.30 * pseudomonas putida 21.0 21.0 1 PMID:2324116 -6.2.1.30 * pseudomonas sp. 24.4 24.4 1 PMID:8352645 -6.2.1.30 * thermus thermophilus 24.0 0.0215 4 PMID:18414813 -6.2.1.31 * pseudomonas putida 0.2 0.2 1 PMID:16347977 -6.2.1.33 * arthrobacter sp. 0.86 0.86 1 PMID:15068371 -6.2.1.33 * pseudomonas sp. 111.6 111.6 1 PMID:1418673 -6.2.1.36 * metallosphaera sedula 18.0 18.0 1 PMID:18165310 -6.2.1.36 * sulfurisphaera tokodaii 6.7 6.7 1 PMID:18165310 -6.2.1.37 * thauera aromatica 14.3 9.21 2 PMID:11208796;PMID:18156265 -6.2.1.4 * pigeon 22.1 22.1 1 PMID:9765290 -6.2.1.40 * metallosphaera sedula 1.7 0.96 2 PMID:23258541 -6.2.1.40 * pyrobaculum neutrophilum 1.6 1.6 1 PMID:21169482 -6.2.1.44 * candidatus pelagibacter communis 28.0 28.0 1 PMID:24443527 -6.2.1.44 * ruegeria lacuscaerulensis 567.4 567.4 1 PMID:30677184 -6.2.1.44 * ruegeria pomeroyi 16.0 15.0 3 PMID:21562561;PMID:24443527 -6.2.1.5 * acetobacter aceti 0.17 0.0985 4 PMID:18502856 -6.2.1.5 * advenella mimigardefordensis 1.0 1.0 2 PMID:24141127 -6.2.1.5 * alcanivorax borkumensis 4.14 4.14 2 PMID:24141127 -6.2.1.5 * calliphoridae 10.0 10.0 1 PMID:4729475 -6.2.1.5 * columba livia 6.61 6.61 1 PMID:9765290 -6.2.1.5 * escherichia coli k-12 18.6 18.6 2 PMID:24141127 -6.2.1.5 * pigeon 0.1 0.1 1 PMID:3940885 -6.2.1.5 * thermococcus kodakarensis 39.4 19.79 2 PMID:17640871 -6.2.1.56 * nitrosopumilus maritimus 20.0 20.0 1 PMID:24843170 -6.2.1.58 * syntrophorhabdus aromaticivorans 0.073 0.073 1 PMID:30647456 -6.2.1.65 * thauera aromatica 328.0 328.0 1 PMID:8661934 -6.2.1.7 * ophiodon elongatus 0.0015 0.0015 1 PMID:2344727 -6.2.1.7 * rattus norvegicus 0.385 0.19340000000000002 2 PMID:3183523;PMID:9390170 -6.2.1.71 * escherichia coli 210.0 8.33 3 PMID:16632253;PMID:2531000 -6.2.1.76 * bradyrhizobium japonicum 22.77 22.77 1 PMID:1847615 -6.2.1.76 * rhizobium leguminosarum 35.46 35.46 1 PMID:9826185 -6.2.1.8 * lathyrus sativus 8.2 8.2 1 PMID:35359497 -6.2.1.9 * pseudomonas sp. 7.4 4.5 3 PMID:429295;PMID:4745770;PMID:7573958 -6.3.1.11 * escherichia coli k-12 12.7 12.7 1 PMID:18495664 -6.3.1.13 * mycobacterium tuberculosis 0.15 0.15 1 PMID:16674910 -6.3.1.13 * mycolicibacterium smegmatis 0.054 0.025 3 PMID:12033919;PMID:16908186 -6.3.1.15 * streptomyces niveus 3.036 3.036 1 PMID:10801869 -6.3.1.17 * mus musculus 0.7 0.7 1 PMID:20657015 -6.3.1.2 * acidithiobacillus ferrooxidans 88.08 88.08 1 * -6.3.1.2 * bacillus subtilis 23.0 12.3 2 PMID:16055443 -6.3.1.2 * bacteroides fragilis 11.0 11.0 1 PMID:21393843 -6.3.1.2 * bifidobacterium bifidum 221.3 221.3 1 * -6.3.1.2 * bifidobacterium breve 73.2 73.2 1 * -6.3.1.2 * bifidobacterium pseudolongum 99.6 99.6 1 * -6.3.1.2 * chlorella sorokiniana 18.5 18.5 1 PMID:16664139 -6.3.1.2 * escherichia coli 1.6 1.6 1 PMID:11673431 -6.3.1.2 * halobacillus halophilus 1.53 1.53 1 PMID:16980483 -6.3.1.2 * haloferax mediterranei 0.0149 0.00755 2 PMID:17020556 -6.3.1.2 * homo sapiens 0.067 0.023 5 PMID:18555765 -6.3.1.2 * klebsiella aerogenes 1.5 1.5 1 PMID:11673431 -6.3.1.2 * lathyrus oleraceus 33.9 33.9 1 PMID:4150338 -6.3.1.2 * leishmania donovani 0.7325 0.52725 2 PMID:28351708 -6.3.1.2 * leptolyngbya laminosa 152.0 78.2 2 PMID:2563365 -6.3.1.2 * lupinus luteus 62.0 62.0 1 * -6.3.1.2 * methanohalophilus portucalensis 7.3 7.3 1 PMID:11571143 -6.3.1.2 * methylococcus capsulatus 306.0 306.0 1 * -6.3.1.2 * nitrobacter winogradskyi 220.0 220.0 1 * -6.3.1.2 * photobacterium phosphoreum 59.3 59.3 1 PMID:2870058 -6.3.1.2 * pseudomonas fluorescens 47.3 47.3 1 PMID:6111557 -6.3.1.2 * pseudomonas syringae 41.6 41.6 1 * -6.3.1.2 * pseudomonas taetrolens 1.17 1.17 1 PMID:15388964 -6.3.1.2 * rattus norvegicus 8.93 5.015 2 PMID:2868383;PMID:2868384 -6.3.1.2 * rhodobacter capsulatus 153.0 153.0 1 PMID:2859272 -6.3.1.2 * schistosoma japonicum 3300.0 3300.0 1 PMID:23011789 -6.3.1.2 * secale cereale x triticum aestivum 35.1 34.3 2 PMID:7732756 -6.3.1.2 * skeletonema costatum 4.27 4.27 1 PMID:8756499 -6.3.1.2 * spinacia oleracea 198.0 198.0 1 PMID:16664546 -6.3.1.2 * squalus acanthias 55.8 55.8 1 PMID:2860871 -6.3.1.2 * sulfolobus acidocaldarius 26.8 26.8 1 PMID:9865608 -6.3.1.2 * sus scrofa 1.0 1.0 1 PMID:2868384 -6.3.1.2 * synechocystis sp. 36.8 36.8 1 PMID:9063472 -6.3.1.2 * trichormus variabilis 126.1 69.1 2 PMID:12732949 -6.3.1.20 * escherichia coli 27.6 19.55 2 PMID:7639702;PMID:8206909 -6.3.1.20 * thermococcus kodakarensis 0.0227 0.01455 6 PMID:35736229 -6.3.1.21 * escherichia coli 52.0 17.3 3 PMID:8117714 -6.3.1.4 * solanum tuberosum 0.0583 0.0583 1 PMID:5820987 -6.3.1.5 * escherichia coli 6.9 1.5 3 PMID:3003498;PMID:4290215 -6.3.1.5 * geobacillus stearothermophilus 1.59 1.59 1 PMID:12450114 -6.3.1.5 * mycobacterium tuberculosis 0.67 0.0665 4 PMID:12182838 -6.3.1.5 * saccharomyces cerevisiae 0.741 0.741 1 PMID:16954203 -6.3.1.5 * streptococcus sobrinus 0.49 0.49 1 PMID:14702311 -6.3.1.8 * crithidia fasciculata 7.9 4.95 2 PMID:12049631;PMID:15537651 -6.3.1.8 * escherichia coli 7.4 7.4 1 PMID:7775463 -6.3.1.9 * crithidia fasciculata 2.1 2.1 1 PMID:15537651 -6.3.1.9 * trypanosoma cruzi 0.77 0.77 1 PMID:12121990 -6.3.2.1 * escherichia coli 2.05 2.05 1 PMID:374975;PMID:780351 -6.3.2.1 * lotus japonicus 1.36 1.36 1 * -6.3.2.10 * escherichia coli 13.9 0.8 13 PMID:11722566;PMID:9166795 -6.3.2.11 * gallus gallus 1.119 1.119 1 PMID:20097752 -6.3.2.12 * escherichia coli 0.535 0.535 1 PMID:2985605 -6.3.2.12 * lathyrus oleraceus 0.007 0.007 1 PMID:239104 -6.3.2.12 * serratia indica 0.0155 0.0155 1 PMID:9496 -6.3.2.13 * bacillus cereus 3.15 3.15 1 PMID:4967958 -6.3.2.13 * escherichia coli 1.24 0.33215 4 PMID:11124264;PMID:11722566;PMID:2269304;PMID:3905407 -6.3.2.13 * pseudomonas aeruginosa 3.31 3.31 1 PMID:11281713 -6.3.2.17 * corynebacterium sp. 0.57 0.57 1 PMID:3084914;PMID:6412521;PMID:6458762;PMID:6892912 -6.3.2.17 * escherichia coli 13.2 0.7235 8 PMID:12051687;PMID:18232714;PMID:2985605 -6.3.2.17 * homo sapiens 0.85 5.45e-05 13 PMID:10029597;PMID:10648167;PMID:10777604;PMID:1409616;PMID:9250977 -6.3.2.17 * lacticaseibacillus casei 11.8 0.23 9 PMID:10970743;PMID:12051687;PMID:12578366;PMID:18232714;PMID:3084914;PMID:6138353 -6.3.2.17 * lathyrus oleraceus 45.6 45.6 1 * -6.3.2.17 * mus musculus 8e-06 1e-07 5 PMID:10856298 -6.3.2.17 * sus scrofa 5.2 2.8325 2 PMID:3828320 -6.3.2.2 * [candida] boidinii 0.013 0.013 1 PMID:10218110 -6.3.2.2 * agrobacterium tumefaciens 2.585 2.585 1 PMID:18346196 -6.3.2.2 * brassica juncea 3.336 3.336 1 PMID:18346196 -6.3.2.2 * drosophila melanogaster 8.45 8.42 2 PMID:12954617 -6.3.2.2 * escherichia coli 51.0 17.3 4 PMID:11675389;PMID:2895925 -6.3.2.2 * homo sapiens 28.75 6.17 11 PMID:10218110;PMID:12663448;PMID:8106072;PMID:9637733;PMID:9675072 -6.3.2.2 * plasmodium berghei 39.5 39.5 1 PMID:19567234 -6.3.2.2 * rattus norvegicus 25.0 9.0 9 PMID:10218110;PMID:10702364;PMID:11969185;PMID:6149706;PMID:7913645 -6.3.2.2 * rhodotorula diobovata 0.25 0.25 2 PMID:29247264 -6.3.2.2 * streptococcus agalactiae 15.3 15.3 1 PMID:15642737 -6.3.2.2 * xanthomonas campestris 2.405 2.405 1 PMID:18346196 -6.3.2.23 * lathyrus oleraceus 3.4 3.4 1 PMID:12010468 -6.3.2.23 * vigna radiata var. radiata 0.042 0.042 1 * -6.3.2.24 * rattus norvegicus 1.6e-06 1.6e-06 1 PMID:3597366 -6.3.2.25 * bos taurus 0.039 0.025 2 PMID:7098992;PMID:861204 -6.3.2.25 * sus scrofa 0.737 0.5305 2 PMID:3965474;PMID:7390974 -6.3.2.26 * amycolatopsis lactamdurans 55.71 55.71 1 PMID:8973642 -6.3.2.26 * streptomyces clavuligerus 0.0113 0.0113 1 PMID:1590759 -6.3.2.26 * thermococcus kodakarensis 15.6 14.7 3 PMID:22940806 -6.3.2.29 * acinetobacter calcoaceticus 0.265 0.265 1 PMID:15289556 -6.3.2.29 * chlorogloeopsis fritschii 0.0065 0.0054 3 * -6.3.2.29 * synechococcus sp. ma19 0.113 0.113 1 PMID:11772614 -6.3.2.29 * trichormus variabilis 0.00221 0.00221 1 PMID:9652408 -6.3.2.3 * [candida] boidinii 0.17 0.17 1 * -6.3.2.3 * escherichia coli 42.83 26.83 2 PMID:3553173;PMID:6389479 -6.3.2.3 * lathyrus oleraceus 0.033 0.033 1 * -6.3.2.3 * mus musculus 43.0 32.75 4 PMID:14743434 -6.3.2.3 * phaseolus vulgaris 0.0094 0.0094 1 PMID:11080313 -6.3.2.3 * plasmodium berghei 29.95 29.95 1 PMID:21377539 -6.3.2.3 * rattus norvegicus 13.75 0.0071 6 PMID:10964706;PMID:12044560;PMID:3911005 -6.3.2.3 * rhodotorula diobovata 0.38 0.38 2 PMID:29247264 -6.3.2.3 * schizosaccharomyces pombe 20.1 17.25 4 PMID:12734194;PMID:8192897 -6.3.2.3 * streptococcus agalactiae 19.33 19.33 1 PMID:15642737 -6.3.2.3 * vigna unguiculata 0.0127 0.0008 3 PMID:11080313 -6.3.2.30 * acinetobacter calcoaceticus 0.265 0.265 1 PMID:15289556 -6.3.2.30 * nostoc ellipsosporum 17.5 17.5 1 PMID:18977318 -6.3.2.30 * synechococcus sp. ma19 0.113 0.113 1 PMID:11772614 -6.3.2.30 * synechocystis sp. 2.01 2.01 1 PMID:20038708 -6.3.2.30 * synechocystis sp. pcc 6803 0.238 0.238 1 PMID:11319097 -6.3.2.30 * trichormus variabilis 0.00221 0.00221 1 PMID:9652408 -6.3.2.33 * methanocaldococcus jannaschii 12.7 12.35 2 PMID:12909715 -6.3.2.35 * enterococcus faecalis 8.2 8.2 1 PMID:19851013 -6.3.2.4 * escherichia coli 31.0 15.6 4 PMID:1554356;PMID:1993184;PMID:1998664 -6.3.2.4 * salmonella enterica subsp. enterica serovar typhimurium 16.4 16.4 1 PMID:2841972 -6.3.2.4 * thermotoga maritima 5.5 0.88 7 PMID:17090922;PMID:21512246 -6.3.2.41 * mus musculus 1.4 1.245 2 PMID:20657015 -6.3.2.43 * thermococcus kodakarensis 0.021 0.021 3 PMID:27566549 -6.3.2.44 * methanosarcina mazei 0.14 0.14 1 PMID:18422645 -6.3.2.45 * escherichia coli 5.6 5.6 1 PMID:17384195 -6.3.2.5 * escherichia coli 0.371 0.371 1 PMID:11278255 -6.3.2.52 * arabidopsis thaliana 0.0298 0.00903 4 PMID:17291501 -6.3.2.6 * ovis aries 11.06 11.06 1 PMID:1781372 -6.3.2.60 * thermococcus kodakarensis 0.016 0.016 1 PMID:27566549 -6.3.2.7 * lysinibacillus sphaericus 0.245 0.245 1 PMID:3718704 -6.3.2.7 * staphylococcus aureus 23.4 11.735 2 PMID:10498701 -6.3.2.8 * bacillus subtilis 0.413 0.413 1 * -6.3.2.8 * chlamydia trachomatis 0.074 0.074 1 PMID:14594822 -6.3.2.8 * escherichia coli 2.94 2.52 2 PMID:7601127;PMID:8634271 -6.3.2.8 * staphylococcus aureus 0.14 0.14 1 PMID:4756894 -6.3.2.9 * escherichia coli 1.92 1.772 3 PMID:1765076;PMID:9631510 -6.3.2.9 * staphylococcus aureus 5.0 2.6065 2 PMID:14213349;PMID:9524242 -6.3.3.1 * escherichia coli 3.35 3.35 1 PMID:3530323 -6.3.3.1 * gallus gallus 0.43 0.375 2 PMID:3756144;PMID:4084560 -6.3.3.2 * homo sapiens 37.0 37.0 1 PMID:3801490 -6.3.3.2 * lacticaseibacillus casei 3.8 3.8 1 PMID:6421815;PMID:6433660 -6.3.3.2 * mus musculus 2.22 2.22 1 PMID:15135403 -6.3.3.2 * mycoplasmoides pneumoniae 2.8 2.8 1 PMID:16104022 -6.3.3.2 * oryctolagus cuniculus 13.0 0.00036 7 PMID:11292595;PMID:9250979 -6.3.3.2 * saccharomyces cerevisiae 7.0 7.0 1 PMID:11923304 -6.3.3.3 * escherichia coli 0.002 0.002 1 PMID:4923070 -6.3.4.10 * bos taurus 0.514 0.514 1 PMID:8053691 -6.3.4.12 * methylovorus mays 8.0 8.0 1 PMID:18175924 -6.3.4.13 * aquifex aeolicus 22.8 13.405000000000001 2 PMID:10850988 -6.3.4.13 * escherichia coli 19.0 10.65 2 PMID:9843369 -6.3.4.13 * gallus gallus 7.2 7.2 1 PMID:3673708 -6.3.4.13 * homo sapiens 0.228 0.228 1 PMID:3718932 -6.3.4.13 * klebsiella aerogenes 1.7 1.7 1 PMID:692385 -6.3.4.15 * candida albicans 0.049 0.049 1 PMID:18809372 -6.3.4.15 * escherichia coli 4.6e-05 4.6e-05 1 PMID:7024555 -6.3.4.16 * aquarana catesbeiana 2.4 2.4 1 PMID:213431 -6.3.4.16 * escherichia coli 12.92 9.315 2 PMID:31307577 -6.3.4.16 * homo sapiens 1.5 1.18 2 PMID:19106093;PMID:4347313;PMID:6249820;PMID:7248316 -6.3.4.16 * methanobrevibacter smithii 0.077 0.04076 2 PMID:23107800 -6.3.4.16 * phycomyces blakesleeanus 0.87 0.87 1 PMID:3395622 -6.3.4.16 * pyrococcus abyssi 0.4 0.20700000000000002 2 PMID:11523892 -6.3.4.16 * pyrococcus furiosus 16.0 13.835 2 PMID:10347186;PMID:9371756 -6.3.4.16 * rattus norvegicus 3.8 1.685 4 PMID:11577071;PMID:182079;PMID:4347313;PMID:6249820;PMID:6797842;PMID:7248316 -6.3.4.18 * escherichia coli 0.23 0.23 1 PMID:19384989 -6.3.4.2 * bos taurus 0.015 0.015 1 PMID:692405;PMID:932036 -6.3.4.2 * escherichia coli 8.7 7.25 2 PMID:357909;PMID:3911002;PMID:6349684 -6.3.4.2 * homo sapiens 0.0025 0.0025 1 PMID:17463002 -6.3.4.2 * mus musculus 0.06 0.06 1 PMID:7306558 -6.3.4.2 * saccharomyces cerevisiae 2.51 1.3 3 PMID:10600130;PMID:12670958;PMID:8075080 -6.3.4.2 * trypanosoma brucei 0.5515 0.25525 4 PMID:17331943 -6.3.4.21 * bos taurus 0.0012 0.0012 1 PMID:13717627 -6.3.4.21 * escherichia coli 23.72 5.7749999999999995 12 PMID:23740313;PMID:24564896 -6.3.4.21 * homo sapiens 0.052 0.0226 5 PMID:17604275;PMID:4349867 -6.3.4.21 * saccharomyces cerevisiae 2.3 2.3 1 PMID:4324895 -6.3.4.21 * salmonella enterica subsp. enterica serovar typhimurium 3.0 3.0 1 PMID:7503993 -6.3.4.21 * sus scrofa 457.3 290.85 4 * -6.3.4.23 * methanocaldococcus jannaschii 1.9 1.9 1 PMID:15623504 -6.3.4.3 * homo sapiens 23.0 23.0 1 PMID:18767138 -6.3.4.3 * methylorubrum extorquens 117.0 117.0 1 PMID:14645277 -6.3.4.3 * neomoorella thermoacetica 780.0 780.0 1 PMID:11087401 -6.3.4.3 * ovis aries 40.0 40.0 1 PMID:6990198 -6.3.4.3 * peptoniphilus asaccharolyticus 200.0 200.0 1 PMID:624720 -6.3.4.3 * saccharomyces cerevisiae 51.3 51.3 1 PMID:6990198 -6.3.4.3 * spinacia oleracea 202.0 202.0 1 PMID:1917961 -6.3.4.4 * dictyostelium discoideum 1.388 1.388 1 PMID:6703692 -6.3.4.4 * escherichia coli 1.731 0.8679650000000001 2 PMID:18312263;PMID:3038024 -6.3.4.4 * halobacterium salinarum 560.0 560.0 1 PMID:9457844 -6.3.4.4 * haloferax volcanii 720.0 720.0 1 PMID:9457844 -6.3.4.4 * homo sapiens 0.00641 0.00641 1 PMID:4436310 -6.3.4.4 * plasmodium falciparum 1144.0 1144.0 1 PMID:12071700 -6.3.4.4 * rattus norvegicus 2.36 2.36 1 PMID:7213642 -6.3.4.4 * zea mays 3.84 3.84 1 PMID:9193088 -6.3.4.5 * bos taurus 3.83 3.815 2 PMID:4355767;PMID:6957859;PMID:885853 -6.3.4.5 * canis lupus familiaris 1e-06 1e-06 1 PMID:12618329 -6.3.4.5 * daucus carota 0.0166 0.0078000000000000005 4 PMID:17142485 -6.3.4.5 * homo sapiens 4.2 0.975 10 PMID:12618329;PMID:16380201;PMID:518841;PMID:6766737;PMID:6885737 -6.3.4.5 * lathyrus oleraceus 12.8 12.8 1 * -6.3.4.5 * mus musculus 5.16 0.63 6 PMID:12618329;PMID:16420741 -6.3.4.5 * pyrococcus furiosus 0.0002 0.0002 1 * -6.3.4.5 * rattus norvegicus 2.1 2.1 1 PMID:5300 -6.3.4.5 * rhizophagus intraradices 0.049 0.0328 4 PMID:17142485 -6.3.4.5 * saccharolobus solfataricus 0.0007 0.000575 2 * -6.3.4.5 * saccharomyces cerevisiae 4.54 4.54 1 PMID:35347 -6.3.4.5 * thermus thermophilus 0.92 0.49 2 PMID:12684518 -6.3.4.6 * cyberlindnera jadinii 12.5 12.5 1 PMID:14157 -6.3.4.6 * saccharomyces cerevisiae 2.44 2.44 1 PMID:4562164 -6.3.4.8 * oryctolagus cuniculus 0.00706 0.00706 1 PMID:14235540 -6.3.4.9 * propionibacterium freudenreichii subsp. shermanii 0.0124 0.0124 1 PMID:3360240 -6.3.5.1 * homo sapiens 0.017 0.017 1 PMID:2107886 -6.3.5.1 * mycobacterium tuberculosis 0.67 0.165 6 PMID:12182838;PMID:9620974 -6.3.5.1 * saccharomyces cerevisiae 2.33 2.1 3 PMID:16954203 -6.3.5.10 * pseudomonas denitrificans (nom. rej.) 0.083 0.083 1 PMID:1917839 -6.3.5.11 * pseudomonas denitrificans (nom. rej.) 1320.0 1320.0 1 PMID:2172209 -6.3.5.2 * escherichia coli 9.09 8.094999999999999 2 PMID:211374;PMID:3911001 -6.3.5.2 * homo sapiens 3.74 3.27 2 PMID:8089153;PMID:8527935 -6.3.5.2 * mus musculus 0.0428 0.0428 1 PMID:211375;PMID:240826 -6.3.5.2 * rattus norvegicus 0.22 0.22 1 PMID:3436958 -6.3.5.3 * escherichia coli 2.15 2.15 1 PMID:2659070 -6.3.5.3 * gallus gallus 0.16 0.16 1 PMID:2939878 -6.3.5.3 * thermotoga maritima 0.037 0.037 1 PMID:18597481 -6.3.5.4 * bos taurus 0.395 0.28250000000000003 2 PMID:2858178;PMID:2868008 -6.3.5.4 * leishmania donovani 0.0696 0.0696 1 PMID:24610810 -6.3.5.4 * lupinus albus 0.193 0.193 1 * -6.3.5.4 * mus musculus 0.096 0.096 1 PMID:39555 -6.3.5.4 * rattus norvegicus 0.57 0.57 1 PMID:6116467 -6.3.5.5 * aquifex aeolicus 0.041 0.041 1 PMID:11574542 -6.3.5.5 * crithidia fasciculata 0.00095 0.00095 1 PMID:3608429 -6.3.5.5 * escherichia coli 0.855 0.855 1 PMID:19106093 -6.3.5.5 * halomonas eurihalina 0.001125 0.001125 1 PMID:12768451 -6.3.5.5 * neurospora crassa 509.0 509.0 1 PMID:2420793 -6.3.5.5 * pseudomonas aeruginosa 2.561 2.561 1 PMID:6402363 -6.3.5.5 * salmonella enterica subsp. enterica serovar typhimurium 4.166 4.166 1 PMID:211376 -6.3.5.6 * chlamydia trachomatis 3.5e-05 3.5e-05 1 PMID:11585842 -6.3.5.7 * bacillus subtilis 0.009 0.009 1 PMID:9342321 -6.3.5.9 * pseudomonas denitrificans (nom. rej.) 0.083 0.07550000000000001 2 PMID:1917839 -6.4.1.1 * [bacillus] caldotenax 3.7 3.7 1 * -6.4.1.1 * ancylobacter novellus 1.03 1.03 1 * -6.4.1.1 * arthrobacter globiformis 27.0 27.0 1 PMID:851353 -6.4.1.1 * gallus gallus 2030.0 1029.5 2 PMID:10858297;PMID:12054488 -6.4.1.1 * geobacillus stearothermophilus 31.5 31.5 1 PMID:4394197 -6.4.1.1 * homo sapiens 47.8 43.8 3 PMID:10600533;PMID:14749229 -6.4.1.1 * mycolicibacterium smegmatis 150.0 150.0 1 PMID:10913817 -6.4.1.1 * phycomyces blakesleeanus 0.074 0.074 1 * -6.4.1.1 * pseudomonas aeruginosa 19.43 2.8525 4 PMID:16997990;PMID:18996187 -6.4.1.1 * pseudomonas fluorescens 9.34 0.03 3 PMID:18996187;PMID:4579 -6.4.1.1 * rattus norvegicus 34.0 18.62 3 PMID:3178228;PMID:3753465 -6.4.1.1 * rhizobium etli 0.81 0.17 9 PMID:11916689 -6.4.1.1 * saccharomyces cerevisiae 0.587 0.587 1 PMID:15063626 -6.4.1.2 * acidianus brierleyi 14.5 14.5 1 PMID:12533469 -6.4.1.2 * acidianus infernus 0.0002 0.0002 1 PMID:9973333 -6.4.1.2 * alopecurus myosuroides 154.9 46.849999999999994 4 PMID:12859251 -6.4.1.2 * anser anser 5.0 5.0 1 PMID:6122424 -6.4.1.2 * brassica napus 0.065 0.065 1 * -6.4.1.2 * chloroflexus aurantiacus 0.015 0.015 1 PMID:9973333 -6.4.1.2 * cyclotella cryptica 14.6 14.6 1 PMID:16667268;PMID:235704 -6.4.1.2 * festuca rubra 184.2 104.55 2 PMID:12859251 -6.4.1.2 * homo sapiens 0.00921 0.00083 4 PMID:17223360;PMID:18760332 -6.4.1.2 * hordeum vulgare 1.508 1.508 1 * -6.4.1.2 * lathyrus oleraceus 0.244 0.121 3 PMID:7957202 -6.4.1.2 * lolium multiflorum 3.5 3.5 1 PMID:12232234 -6.4.1.2 * metallosphaera sedula 3.2 1.6065 2 PMID:12581213;PMID:9973333 -6.4.1.2 * mycosarcoma maydis 0.3 0.3 1 PMID:14766011 -6.4.1.2 * oryctolagus cuniculus 4.2 4.2 1 PMID:6116159 -6.4.1.2 * rattus norvegicus 26.93 4.325 10 PMID:11205884;PMID:11978655;PMID:16667268;PMID:19500808;PMID:235704;PMID:24055;PMID:6116153;PMID:6116163;PMID:7628470 -6.4.1.2 * rhizobium etli 7.27 0.006 7 PMID:14766918 -6.4.1.2 * ricinus communis 2.052 2.052 1 PMID:6137995 -6.4.1.2 * saccharomyces cerevisiae 6.0 3.00000066 2 PMID:21953464;PMID:6116162 -6.4.1.2 * solanum tuberosum 8.6e-05 4.75e-05 2 PMID:15014998 -6.4.1.2 * staphylococcus aureus 0.4 0.4 1 PMID:15066985 -6.4.1.2 * sulfuracidifex metallicus 0.0025 0.0025 1 PMID:9973333 -6.4.1.2 * zea mays 217.0 20.22 4 PMID:12231704;PMID:12859251;PMID:6141767 -6.4.1.3 * acidianus brierleyi 11.9 11.9 1 PMID:12533469 -6.4.1.3 * agrobacterium tumefaciens 0.00186 0.00186 1 PMID:14766918 -6.4.1.3 * azorhizobium caulinodans 0.01177 0.01177 1 PMID:14766918 -6.4.1.3 * bradyrhizobium japonicum 0.0248 0.0248 1 PMID:14766918 -6.4.1.3 * homo sapiens 27.7 23.35 3 PMID:15890657;PMID:6765947;PMID:7396525 -6.4.1.3 * mesorhizobium huakuii 0.00483 0.00483 1 PMID:14766918 -6.4.1.3 * mesorhizobium loti 0.00199 0.00199 1 PMID:14766918 -6.4.1.3 * metallosphaera sedula 3.3 3.3 1 PMID:12581213 -6.4.1.3 * mycolicibacterium smegmatis 9.7 9.7 1 PMID:447686 -6.4.1.3 * myxococcus xanthus 14.13 14.13 1 PMID:9683657 -6.4.1.3 * rhizobium etli 7.27 7.27 1 PMID:14766918 -6.4.1.3 * rhizobium leguminosarum bv. viciae 0.00459 0.00459 1 PMID:14766918 -6.4.1.3 * rhizobium tropici 0.00535 0.00535 1 PMID:14766918 -6.4.1.3 * sinorhizobium fredii 0.00442 0.00442 1 PMID:14766918 -6.4.1.3 * sinorhizobium meliloti 0.00673 0.00673 1 PMID:14766918 -6.4.1.3 * sus scrofa 5.6 5.6 1 PMID:13752080 -6.4.1.4 * achromobacter sp. 9.36 9.36 1 * -6.4.1.4 * bos taurus 3.84 3.77 2 PMID:7278687;PMID:7469416 -6.4.1.4 * glycine max 0.3367 0.3367 1 PMID:10989437 -6.4.1.4 * hordeum vulgare 0.1182 0.1182 1 * -6.4.1.4 * lathyrus oleraceus 4.5 4.5 1 PMID:12231881 -6.4.1.4 * pseudomonas citronellolis 10.54 10.54 1 PMID:7278686;PMID:911753 -6.4.1.4 * solanum tuberosum 2.77 2.77 1 PMID:12231881 -6.4.1.4 * xanthomonas citri pv. citri 3.2 3.2 1 PMID:29879157 -6.4.1.4 * zea mays 0.2062 0.2061 2 PMID:10989437;PMID:8161223 -6.4.1.5 * pseudomonas citronellolis 8.38 8.38 1 PMID:7278686;PMID:911753 -6.4.1.5 * zea mays 0.138 0.138 1 PMID:9917324 -6.4.1.6 * rhodococcus rhodochrous 0.07 0.015 4 PMID:10217764 -6.4.1.6 * xanthobacter autotrophicus 0.24 0.24 1 PMID:12003937 -6.4.1.6 * xanthobacter versatilis 0.225 0.1595 2 PMID:9237998 -6.4.1.8 * aromatoleum aromaticum 0.051 0.051 1 PMID:20047908 -6.5.1.3 * tequatrovirus t4 0.06 0.016 9 PMID:10215898;PMID:19414000;PMID:4342972 -6.5.1.3 * triticum aestivum 0.00152 0.00152 1 PMID:2166219 -6.5.1.4 * homo sapiens 0.021 0.021 1 PMID:2581947 -6.5.1.9 * methanothermobacter thermautotrophicus 0.1548 0.07925 2 * -6.5.1.9 * methanothermus fervidus 29.0 7.875 6 PMID:2226838;PMID:9811660 -6.6.1.1 * lathyrus oleraceus 0.0001 2.6e-06 5 PMID:11607197;PMID:19605356 -7.1.1.1 * bos taurus 62.3 15.2 8 PMID:2005110;PMID:26313;PMID:3272340;PMID:459845;PMID:6234316;PMID:6487611;PMID:7068624;PMID:7462228;PMID:921770 -7.1.1.1 * cereibacter sphaeroides 50.8 50.8 1 PMID:11751816 -7.1.1.1 * escherichia coli 63.0 1.46 23 PMID:11779549;PMID:15177281;PMID:15935988;PMID:3009227;PMID:368063;PMID:3891338;PMID:7703264;PMID:795430;PMID:8112317;PMID:9182734 -7.1.1.1 * klebsiella pneumoniae 0.26 0.26 1 PMID:8117298 -7.1.1.1 * rattus norvegicus 2.6 2.6 1 PMID:4061827 -7.1.1.1 * rhodobacter capsulatus 3.78 3.78 1 PMID:1849819 -7.1.1.12 * bacillus licheniformis 6.1 6.1 1 PMID:17154542 -7.1.1.2 * aquifex aeolicus 1.3 1.25 2 PMID:11852056 -7.1.1.2 * beta vulgaris 3.4 3.4 1 PMID:16668682 -7.1.1.2 * bos taurus 18.6 18.6 1 PMID:26592861 -7.1.1.2 * corynebacterium glutamicum 273.0 158.5 2 PMID:15665480 -7.1.1.2 * escherichia coli 90.0 2.2 9 PMID:11997136;PMID:12637579;PMID:14970214;PMID:15938640;PMID:15996109;PMID:16849371;PMID:16979134 -7.1.1.2 * homo sapiens 7.52 7.145 2 PMID:26063804 -7.1.1.2 * methylococcus capsulatus 55.0 55.0 1 PMID:11811946 -7.1.1.2 * paracoccus denitrificans 1.144 0.6525 2 PMID:16849371 -7.1.1.2 * rattus norvegicus 102.0 24.555 8 PMID:11875069;PMID:17270175 -7.1.1.2 * saccharomyces cerevisiae 1671.0 866.45 2 PMID:3138118 -7.1.1.2 * solanum tuberosum 11.5 11.5 1 PMID:8294484 -7.1.1.2 * sulfuracidifex metallicus 195.0 195.0 1 PMID:12615344 -7.1.1.2 * thermus thermophilus 20.0 1.23 3 PMID:23370906 -7.1.1.2 * trypanosoma brucei 4.8 4.8 1 PMID:11863445 -7.1.1.2 * yarrowia lipolytica 64.0 5.5 7 PMID:11245800;PMID:15572358;PMID:15985426;PMID:16289468 -7.1.1.3 * escherichia coli 960.0 960.0 1 PMID:1322173 -7.1.1.4 * sulfolobus acidocaldarius 36.0 22.95 2 PMID:2166661;PMID:7984110 -7.1.1.7 * escherichia coli 17.3 11.5 6 PMID:8626304 -7.1.1.8 * bos taurus 160.0 112.5 2 PMID:2994720;PMID:6276404 -7.1.1.8 * cereibacter sphaeroides 12.6 12.6 1 PMID:6295373 -7.1.1.8 * paracoccus denitrificans 469.0 235.175 2 PMID:18774933 -7.1.1.9 * acidithiobacillus ferrooxidans 52.5 27.6 2 PMID:18603796 -7.1.1.9 * ancylobacter novellus 10.4 10.4 1 PMID:6248108 -7.1.1.9 * bacillus sp. ps3 0.217 0.217 1 PMID:6087899 -7.1.1.9 * bos taurus 0.018 0.018 1 * -7.1.1.9 * crithidia fasciculata 0.033 0.033 1 PMID:8844671 -7.1.1.9 * cytobacillus firmus 12.0 12.0 1 PMID:6327654 -7.1.1.9 * erythrobacter longus 8.4 8.4 1 PMID:2830243 -7.1.1.9 * ipomoea batatas 147.0 147.0 1 * -7.1.1.9 * leptolyngbya boryana 0.05 0.030000000000000002 2 * -7.1.1.9 * leptolyngbya foveolarum 3.58 3.58 1 * -7.1.1.9 * mus musculus 0.51 0.315 2 PMID:19343276 -7.1.1.9 * mytilus edulis 0.05 0.041 2 PMID:19097171 -7.1.1.9 * nitrobacter winogradskyi 114.0 114.0 1 PMID:6260762 -7.1.1.9 * nitrosomonas europaea 0.258 0.13605 2 * -7.1.1.9 * pseudomonas aeruginosa 111.0 57.5 2 PMID:6281067 -7.1.1.9 * pseudomonas sp. 24.0 24.0 1 PMID:2999096 -7.1.1.9 * rhodopseudomonas palustris 50.7 50.7 1 PMID:9286 -7.1.1.9 * saccharomyces cerevisiae 190.0 190.0 1 PMID:4346952 -7.1.1.9 * synechococcus elongatus pcc 7942 = fachb-805 0.06 0.0375 2 * -7.1.1.9 * synechocystis sp. 0.02 0.01125 2 * -7.1.1.9 * trichormus variabilis 121.7 0.38 3 * -7.1.2.1 * arabidopsis thaliana 32.6 32.6 1 PMID:9473454 -7.1.2.1 * beta vulgaris 25.4 25.4 1 PMID:2142002 -7.1.2.2 * acetabularia acetabulum 4.1 4.1 1 PMID:7764691 -7.1.2.2 * bacillus sp. (in: firmicutes) 54.0 30.0 4 PMID:15355991 -7.1.2.2 * bos taurus 100.0 3.25 3 PMID:19379707 -7.1.2.2 * escherichia coli 12.9 12.9 1 PMID:2908464 -7.1.2.2 * gallus gallus 25.2 25.2 1 PMID:1451435 -7.1.2.2 * haloferax volcanii 0.0314 0.0182 3 PMID:9045643 -7.1.2.2 * mycolicibacterium smegmatis 1.75 0.63 3 PMID:32525613 -7.1.2.2 * rattus norvegicus 2.402 2.402 1 PMID:19650768 -7.1.3.1 * ascaris suum 937.0 937.0 1 PMID:12823552 -7.1.3.1 * beta vulgaris 0.15 0.15 1 PMID:12226285 -7.1.3.1 * escherichia coli 1.3 1.3 1 PMID:14670604 -7.1.3.1 * sesamum indicum 11.66 11.66 1 PMID:11989717 -7.1.3.1 * vigna radiata 0.3 0.3 1 PMID:12226285 -7.2.1.1 * klebsiella pneumoniae 0.77 0.495 2 PMID:16621819 -7.2.1.2 * thermotoga maritima 97.0 97.0 1 PMID:32770029 -7.2.1.3 * rattus norvegicus 6.5 3.2648 2 PMID:5363650;PMID:924372 -7.2.1.3 * sus scrofa 0.0163 0.0163 1 PMID:4154897 -7.2.1.4 * methanosarcina mazei 268.3 10.4 5 PMID:1447136;PMID:7730249;PMID:8774736 -7.2.1.4 * methanothermobacter marburgensis 3.0 2.8 2 PMID:11248186;PMID:8477726 -7.2.1.4 * methanothermobacter thermautotrophicus 11.9 11.9 1 PMID:1737047 -7.2.2.1 * alkalithermobacter thermoalcaliphilus 15.0 3.55 4 PMID:16816177 -7.2.2.1 * enterococcus hirae 4.73 2.3655700000000004 2 PMID:11983695;PMID:7706221 -7.2.2.1 * pyrococcus furiosus 5.8 5.8 1 PMID:17614964 -7.2.2.10 * arabidopsis thaliana 0.1181 0.0711 2 PMID:21073872 -7.2.2.10 * bos taurus 6.5 5.285 2 PMID:16278046;PMID:22387132 -7.2.2.10 * canis lupus familiaris 0.49 0.49 1 PMID:14766300 -7.2.2.10 * homo sapiens 1.5 0.845 2 PMID:2852753 -7.2.2.10 * oryctolagus cuniculus 10.06 9.0 3 PMID:16040761;PMID:16603381;PMID:22387132 -7.2.2.12 * homarus americanus 0.002082 0.001767 6 * -7.2.2.13 * bos taurus 19.84 15.9 2 PMID:19101784 -7.2.2.13 * canis lupus 65.0 48.5 2 PMID:18465843 -7.2.2.13 * clibanarius vittatus 0.1835 0.1835 1 PMID:29356455 -7.2.2.13 * homo sapiens 0.267 0.2165 4 PMID:20132239 -7.2.2.13 * macrobrachium olfersii 686.1 472.6 2 PMID:11691603 -7.2.2.13 * oryctolagus cuniculus 700.0 371.0 2 PMID:12831774 -7.2.2.13 * ovis aries 1105.0 1105.0 1 PMID:15096042 -7.2.2.13 * rattus norvegicus 0.165 0.085 3 PMID:12034138;PMID:15840034 -7.2.2.13 * sus scrofa 65.0 32.0 3 PMID:18465843;PMID:25624492 -7.2.2.14 * mus musculus 1.3e-07 1.15e-07 2 PMID:18992802 -7.2.2.14 * mytilus galloprovincialis 0.5 0.375 2 PMID:18261881 -7.2.2.14 * rattus norvegicus 0.121 0.119 3 PMID:18816301;PMID:18937033 -7.2.2.19 * cavia porcellus 2.045 0.544 3 PMID:20122893 -7.2.2.19 * homo sapiens 0.685 0.611 3 PMID:17137554 -7.2.2.19 * sus scrofa 7.5 2.383 5 PMID:15749775;PMID:16169880;PMID:17696364 -7.2.2.2 * cupriavidus metallidurans 0.2 0.06 3 PMID:28001366 -7.2.2.3 * acetobacterium woodii 16.0 16.0 1 PMID:8033902 -7.2.2.3 * aphanothece halophytica 0.4667 0.24665 2 PMID:20691102 -7.2.2.3 * caloramator fervidus 0.088 0.088 1 PMID:9023212 -7.2.2.3 * enterococcus hirae 26.0 15.365 2 PMID:10788452;PMID:7706221 -7.2.2.3 * ilyobacter tartaricus 20.7 20.7 1 PMID:9642181 -7.2.2.3 * leishmania amazonensis 0.0294 0.008154999999999999 12 PMID:17825292 -7.2.2.3 * propionigenium modestum 3.0 3.0 1 PMID:8325855 -7.2.2.3 * sus scrofa 8.4e-06 6.5e-06 2 PMID:20206222 -7.2.2.6 * alicyclobacillus acidocaldarius 0.56 0.56 1 PMID:2527329 -7.2.2.6 * cereibacter sphaeroides 2.5 2.5 1 PMID:1400242 -7.2.2.6 * clostridium acetobutylicum 4073.0 695.0 6 * -7.2.2.6 * escherichia coli 15.0 6.232 4 PMID:10608856;PMID:2849541;PMID:8672505 -7.2.2.6 * jamaicana flava 0.0339 0.0339 1 PMID:6317792 -7.2.2.6 * locusta migratoria 0.2298 0.2298 1 PMID:6317792 -7.2.2.6 * manduca sexta 0.03 0.03 1 PMID:6317792 -7.2.2.6 * schistocerca gregaria 0.0715 0.0715 1 PMID:6317792 -7.2.2.8 * enterococcus hirae 1.046 0.44000000000000006 6 PMID:29864148 -7.2.2.8 * mycobacterium tuberculosis 0.012 0.012 1 PMID:32054527 -7.2.2.9 * homo sapiens 0.112 0.0965 2 PMID:19520855 -7.2.3.1 * acetobacterium woodii 70.0 70.0 1 PMID:21173152 -7.2.4.2 * klebsiella aerogenes 46.3 27.65 2 PMID:3520232;PMID:6418543 -7.2.4.2 * klebsiella pneumoniae 45.0 45.0 1 PMID:10757980 -7.2.4.2 * salmonella enterica subsp. enterica serovar typhimurium 0.3 0.3 1 PMID:2556085 -7.2.4.4 * malonomonas rubra 42.0 22.335 2 PMID:1628643;PMID:18251085 -7.2.4.5 * syntrophus gentianae 48.0 48.0 2 * -7.3.2.7 * caenorhabditis elegans 28.87 28.87 1 PMID:17419726 -7.3.2.7 * escherichia coli 0.327 0.20450000000000002 2 PMID:11964412 -7.4.2.1 * saccharomyces cerevisiae 0.0332 0.0332 1 PMID:21526172 -7.4.2.5 * homo sapiens 2.02 0.0002525 36 PMID:11274390;PMID:17977821;PMID:18434309 -7.4.2.5 * pseudomonas aeruginosa 0.052 0.0065 5 PMID:16427308 -7.4.2.8 * chlamydia pneumoniae 0.15 0.15 1 PMID:20096108 -7.4.2.8 * escherichia coli 0.28 0.28 1 PMID:27630634 -7.4.2.8 * myxococcus xanthus 0.0029 0.0029 1 PMID:18223089 -7.4.2.8 * pseudomonas aeruginosa 0.0108 0.0074 3 PMID:18174131 -7.4.2.8 * salmonella enterica 0.36 0.36 1 PMID:24722491 -7.4.2.8 * thermus thermophilus 0.0227 0.0227 1 PMID:29464394 -7.4.2.8 * vibrio splendidus 5.86 5.86 1 * -7.5.2.1 * alicyclobacillus acidocaldarius 0.13 0.13 1 PMID:15136159 -7.5.2.1 * escherichia coli 0.011 0.011 1 PMID:2026607 -7.5.2.1 * salmonella enterica subsp. enterica serovar typhimurium 1.25 1.25 1 PMID:12225853 -7.5.2.1 * thermococcus litoralis 0.22 0.22 1 PMID:11453995 -7.5.2.6 * escherichia coli 0.835 0.7295 2 PMID:18803398 -7.5.2.6 * pseudomonas aeruginosa 0.1445 0.1445 1 PMID:17644517 -7.5.2.6 * salmonella enterica subsp. enterica serovar typhimurium 0.4 0.4 1 PMID:19132955 -7.6.2.1 * bos taurus 35.0 17.527 2 PMID:19778899 -7.6.2.1 * escherichia coli 0.002 0.002 1 PMID:12119303 -7.6.2.1 * homo sapiens 45.0 45.0 1 PMID:19778899 -7.6.2.1 * mus musculus 4.9 3.6 2 PMID:16618126 -7.6.2.11 * escherichia coli 0.4 0.4 1 PMID:11421274 -7.6.2.2 * bacillus subtilis 7.0 3.925 4 PMID:12968023;PMID:15182191;PMID:18215075 -7.6.2.2 * helicoverpa armigera 0.4 0.4 1 PMID:20188065 -7.6.2.2 * homo sapiens 3500.0 0.25 13 PMID:19233288;PMID:19323275;PMID:19456124;PMID:22542979;PMID:24825346 -7.6.2.4 * rattus norvegicus 0.0774 0.07585 2 PMID:16946495 -7.6.2.8 * escherichia coli 0.98 0.385 4 PMID:16331991 -7.6.2.9 * lactococcus lactis 0.18 0.099 11 PMID:11742979 diff --git a/doc/index.html b/doc/index.html index 3ab7d918..65aafbd2 100644 --- a/doc/index.html +++ b/doc/index.html @@ -3,8 +3,8 @@ Matlab Index - - + + @@ -15,26 +15,39 @@

Matlab Index

Matlab Directories

+
  • src/change_model
  • src/deprecated
  • src/download_databases
  • src/enzyme_usage
  • src/flux_analysis
  • src/gather_kcats
  • src/get_enzyme_data
  • src/io
  • src/kcat_tuning
  • src/kcat_tuning/evotune
  • src/limit_proteins
  • src/model_adapter
  • src/utilities
  • Matlab Files found in these Directories

    - - - - - - - - - - - - - - - -
    ModelAdapter ecFVA getStandardKcat removeStandardKcat
    ModelAdapterManager enzymeUsage getSubsetEcModel reportEnzymeUsage
    abc_max fillEnzConcs getrSample runDLKcat
    adapterTemplate findECInDB loadBRENDAdata saveEcModel
    addCarbonNum findGECKOroot loadBayesianData selectKcatValue
    addNewRxnsToEC findMaxValue loadConventionalGEM sensitivityTuning
    applyComplexData findMetSmiles loadDatabases setKcatForReactions
    applyCustomKcats flexibilizeEnzConcs loadEcModel setProtPoolSize
    applyKcatConstraints fuzzyKcatMatching loadFluxData sigmaFitter
    bayesianSensitivityTuning getComplexData loadProtData startGECKOproject
    calculateFfactor getConcControlCoeffs makeEcModel truncateValues
    calculateMW getECfromDatabase mapRxnsToConv updateGECKOdoc
    constrainEnzConcs getECfromGEM mergeDLKcatAndFuzzyKcats updateProtPool
    constrainFluxData getECstring mse updateprior
    copyECtoGEM getKcatAcrossIsozymes plotEcFVA writeDLKcatInput
    ecFSEOF getReactionsFromEnzyme readDLKcatOutput
    + ModelAdapter ecTreeEstimate kcatsFromDLKcat resolveKcatAggregation + ModelAdapterManager enzymeUsage kcatsFromECTree resolveOkpApiKey + TomlAdapter evotuneScore kcatsFromHomologs resolveTunableContext + adapterTemplate extractEnzymeSubstratePairs kcatsFromOKP reviewKcatAssignment + addCarbonNum fetchBrendaAsset loadAdapterParams runDLKcat + addNewRxnsToEC fetchOpenKineticsPredictor loadBRENDAdata saveEcModel + applyComplexData fillCarbonNum loadBrendaMeasurements saveKcatSource + applyCustomKcats fillEnzConcs loadConventionalGEM screenKcatLeverage + applyECcodes findECInDB loadDatabases selectKcatValue + applyKcatConstraints findGECKOroot loadEcModel selectTunableMask + assignKcatValues findMetSmiles loadEvotuneData sensitivityTuning + assignKcats flexibilizeEnzConcs loadFluxData setKcatForReactions + bestParsimonious fuzzyKcatMatching loadKcatSource setProtPoolSize + buildGECKOdoc getComplexData loadProtData sigmaFitter + calculateFfactor getConcControlCoeffs makeEcModel startGECKOproject + calculateMW getECfromDatabase mapRxnsToConv submitOpenKineticsPredictor + cmaesKcatTuning getECfromGEM mergeDLKcatAndFuzzyKcats truncateValues + collectKcats getECstring mergeKcats tunePriorPenaltyWeight + constrainEnzConcs getEcRxnKeys nChanged updateGECKOdoc + constrainFluxData getEnzymeBottlenecks parseGECKOargs updateKcatSources + convertAdapterToToml getEnzymeUsage parsimonyFrontier updateProtPool + convertCustomKcats getKcatAcrossIsozymes pfbaEnzymes upgradeEcModel + copyECtoGEM getPfbaEnzymes plotEcFVA upgradeGECKOproject + createGECKOproject getReactionsFromEnzyme readAdapterToml writeAdapterToml + downloadKEGG getStandardKcat readDLKcatOutput writeDLKcatInput + downloadUniProt getSubsetEcModel readOpenKineticsPredictorOutput writeOpenKineticsPredictorInput + ecFSEOF isozymeTieMap relaxProteomicsGreedy + ecFVA kcatAssignmentConfig removeStandardKcat + ecStatsFromBrenda kcatsFromBrenda reportEnzymeUsage
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    diff --git a/doc/src/change_model/addNewRxnsToEC.html b/doc/src/change_model/addNewRxnsToEC.html new file mode 100644 index 00000000..0d5c21ec --- /dev/null +++ b/doc/src/change_model/addNewRxnsToEC.html @@ -0,0 +1,437 @@ + + + + Description of addNewRxnsToEC + + + + + + + + + +
    Home > src > change_model > addNewRxnsToEC.m
    + + + +

    addNewRxnsToEC +

    + +

    PURPOSE ^

    +
    addNewRxnsToEC Add new reactions to an enzyme-constrained model.
    + +

    SYNOPSIS ^

    +
    function [model, rxnsAdded, enzAdded] = addNewRxnsToEC(model, newRxns, varargin)
    + +

    DESCRIPTION ^

    +
     addNewRxnsToEC  Add new reactions to an enzyme-constrained model.
    +
    + Adds new reactions to an enzyme-constrained model. This function is
    + useful to simulate metabolic manipulations done to an organism such as
    + integration of new genes that add a new reaction/pathway.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    + newRxns : struct
    +     structure with the new reaction information (see Notes for fields).
    +
    + Name-Value Arguments
    + --------------------
    + newEnzymes : struct
    +     structure with the new enzymes information (see Notes for fields).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + model : struct
    +     ecModel with new reactions.
    + rxnsAdded : cell
    +     cell array with the reactions added.
    + enzAdded : cell
    +     cell array with the enzymes added.
    +
    + Notes
    + -----
    + The newRxns structure has the following fields:
    +
    + - rxns : cell array with unique strings that identifies each reaction.
    + - rxnNames : cell array with the names of each reaction.
    + - equations : cell array with equation strings. Decimal coefficients are expressed as "1.2". Reversibility is indicated by "<=>" or "=>".
    + - grRules : cell array with the gene-reaction relationship for each reaction. For example "(A and B) or (C)" means that the reaction could be catalyzed by a complex between A & B or by C on its own. A rule with brackets is split into its isozymes in disjunctive normal form, so "A and (B or C)" is the two isozymes "A and B" and "A and C". All the genes have to be present in model.genes. Add genes with addGenesRaven before calling this function if needed (opt, default '').
    +
    + The newEnzymes structure has the following fields:
    +
    + - enzymes : cell array with uniprot id.
    + - genes : cell array with the respective gene.
    + - mw : cell array with the MW.
    +
    + Additional usage notes:
    +
    + 1. Write equations as follows:
    +        'xylitol[c] + NAD[c] => D-xylulose[c] + NADH[c] + H+[c]'
    +    Note that the reversibility defined in the equation will be used to
    +    split to construct irreversible reactions (add _REV) and the rules
    +    defined will be used to expand the model (add _EXP_n).
    + 2. After adding the new reactions, setKcatForReactions or
    +    applyCustomKcats should be run to add the kcat to the reactions, and
    +    subsequently applyKcatConstraints.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     [model, rxnsAdded, enzAdded] = addNewRxnsToEC(model, newRxns, newEnzymes, modelAdapter);
    +     [model, rxnsAdded, enzAdded] = addNewRxnsToEC(model, newRxns, 'newEnzymes', newEnzymes);
    +
    + See also
    + --------
    + applyKcatConstraints, applyCustomKcats
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [model, rxnsAdded, enzAdded] = addNewRxnsToEC(model, newRxns, varargin)
    +0002 % addNewRxnsToEC  Add new reactions to an enzyme-constrained model.
    +0003 %
    +0004 % Adds new reactions to an enzyme-constrained model. This function is
    +0005 % useful to simulate metabolic manipulations done to an organism such as
    +0006 % integration of new genes that add a new reaction/pathway.
    +0007 %
    +0008 % Parameters
    +0009 % ----------
    +0010 % model : struct
    +0011 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0012 % newRxns : struct
    +0013 %     structure with the new reaction information (see Notes for fields).
    +0014 %
    +0015 % Name-Value Arguments
    +0016 % --------------------
    +0017 % newEnzymes : struct
    +0018 %     structure with the new enzymes information (see Notes for fields).
    +0019 % modelAdapter : ModelAdapter
    +0020 %     a loaded model adapter (default: the current default model adapter).
    +0021 %
    +0022 % Returns
    +0023 % -------
    +0024 % model : struct
    +0025 %     ecModel with new reactions.
    +0026 % rxnsAdded : cell
    +0027 %     cell array with the reactions added.
    +0028 % enzAdded : cell
    +0029 %     cell array with the enzymes added.
    +0030 %
    +0031 % Notes
    +0032 % -----
    +0033 % The newRxns structure has the following fields:
    +0034 %
    +0035 % - rxns : cell array with unique strings that identifies each reaction.
    +0036 % - rxnNames : cell array with the names of each reaction.
    +0037 % - equations : cell array with equation strings. Decimal coefficients are expressed as "1.2". Reversibility is indicated by "<=>" or "=>".
    +0038 % - grRules : cell array with the gene-reaction relationship for each reaction. For example "(A and B) or (C)" means that the reaction could be catalyzed by a complex between A & B or by C on its own. A rule with brackets is split into its isozymes in disjunctive normal form, so "A and (B or C)" is the two isozymes "A and B" and "A and C". All the genes have to be present in model.genes. Add genes with addGenesRaven before calling this function if needed (opt, default '').
    +0039 %
    +0040 % The newEnzymes structure has the following fields:
    +0041 %
    +0042 % - enzymes : cell array with uniprot id.
    +0043 % - genes : cell array with the respective gene.
    +0044 % - mw : cell array with the MW.
    +0045 %
    +0046 % Additional usage notes:
    +0047 %
    +0048 % 1. Write equations as follows:
    +0049 %        'xylitol[c] + NAD[c] => D-xylulose[c] + NADH[c] + H+[c]'
    +0050 %    Note that the reversibility defined in the equation will be used to
    +0051 %    split to construct irreversible reactions (add _REV) and the rules
    +0052 %    defined will be used to expand the model (add _EXP_n).
    +0053 % 2. After adding the new reactions, setKcatForReactions or
    +0054 %    applyCustomKcats should be run to add the kcat to the reactions, and
    +0055 %    subsequently applyKcatConstraints.
    +0056 %
    +0057 % Examples
    +0058 % --------
    +0059 %     % optional arguments may be given positionally or as name-value pairs:
    +0060 %     [model, rxnsAdded, enzAdded] = addNewRxnsToEC(model, newRxns, newEnzymes, modelAdapter);
    +0061 %     [model, rxnsAdded, enzAdded] = addNewRxnsToEC(model, newRxns, 'newEnzymes', newEnzymes);
    +0062 %
    +0063 % See also
    +0064 % --------
    +0065 % applyKcatConstraints, applyCustomKcats
    +0066 
    +0067 p = parseGECKOargs(varargin, { ...
    +0068     'newEnzymes',   []; ...
    +0069     'modelAdapter', []});
    +0070 newEnzymes   = p.newEnzymes;
    +0071 modelAdapter = p.modelAdapter;
    +0072 
    +0073 if isempty(modelAdapter)
    +0074     modelAdapter = ModelAdapterManager.getDefault();
    +0075     if isempty(modelAdapter)
    +0076         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0077     end
    +0078 end
    +0079 params = modelAdapter.getParameters();
    +0080 
    +0081 if isempty(newEnzymes)
    +0082     newEnzymes = [];
    +0083 end
    +0084 
    +0085 % Validate if GECKO version 3
    +0086 if ~isfield(model, 'ec')
    +0087     error('Input model is not an ecModel in GECKO 3 format (with ecModel.ec structure)')
    +0088 end
    +0089 
    +0090 if model.ec.geckoLight
    +0091     error('addNewRxnsToEC only works on non-light ecModels')
    +0092 else
    +0093     % Check if the new proteins are not already present in the model
    +0094     if ~isempty(newEnzymes)
    +0095         [toRemove,~] = ismember(newEnzymes.enzymes, model.ec.enzymes);
    +0096 
    +0097         % Remove from the list those enzymes that already present
    +0098         if any(toRemove)
    +0099             printOrange(['WARNING: Enzymes ' strjoin(newEnzymes.enzymes(toRemove),', ') ' are already present in the model and will not be added.\n']);
    +0100             newEnzymes.enzymes(toRemove) = [];
    +0101             newEnzymes.genes(toRemove) = [];
    +0102             newEnzymes.mw(toRemove) = [];
    +0103         end
    +0104 
    +0105         if ~isempty(newEnzymes.enzymes)
    +0106             
    +0107             % 1. Add new genes
    +0108             genesToAdd.genes = newEnzymes.genes;
    +0109             genesToAdd.geneShortNames = genesToAdd.genes;
    +0110             model = addGenesRaven(model, genesToAdd);
    +0111 
    +0112             % 2. Add new Enzyme-usage pseudometabolite
    +0113 
    +0114             % Validate compartment to add protein pseudoreactions
    +0115             compartmentID = strcmp(model.compNames,params.enzyme_comp);
    +0116             if ~any(compartmentID)
    +0117                 error(['Compartment ' params.enzyme_comp ' (specified in params.enzyme_comp) '...
    +0118                     'cannot be found in model.compNames'])
    +0119             end
    +0120             compartmentID = model.comps(compartmentID);
    +0121 
    +0122             proteinMets.mets         = strcat('prot_', newEnzymes.enzymes);
    +0123             proteinMets.metNames     = proteinMets.mets;
    +0124             proteinMets.compartments = compartmentID;
    +0125             if isfield(model,'metMiriams')
    +0126                 proteinMets.metMiriams = repmat({struct('name',{{'sbo'}},'value',{{'SBO:0000252'}})},numel(proteinMets.mets),1);
    +0127             end
    +0128             if isfield(model,'metCharges')
    +0129                 proteinMets.metCharges = zeros(numel(proteinMets.mets),1);
    +0130             end
    +0131             proteinMets.metNotes = repmat({'Enzyme-usage pseudometabolite'},numel(proteinMets.mets),1);
    +0132             model = addMets(model,proteinMets);
    +0133         end
    +0134         enzAdded = newEnzymes.enzymes(:);  
    +0135     end
    +0136 
    +0137     % 3. Add new reactions
    +0138 
    +0139     % The operators of a gene rule are case insensitive: write them in lower
    +0140     % case, as the rest of the function and RAVEN's addRxns expect. Gene ids
    +0141     % that contain the letters (Sand1, andA, ORF1) are left as they are.
    +0142     newRxns.grRules = regexprep(convertCharArray(newRxns.grRules), ...
    +0143         '(?<![^\s()])(and|or)(?![^\s()])', '${lower($0)}', 'ignorecase');
    +0144 
    +0145     % Before add the reactions validate that all the genes in grRules are
    +0146     % present in the model.
    +0147     genesInRules = strjoin(newRxns.grRules);
    +0148     genesInRules = regexp(genesInRules,'[^\s()]+','match'); % Gene ids and the words 'and' and 'or', without spaces and brackets
    +0149     genesInRules = genesInRules(~ismember(lower(genesInRules),{'and','or'}));  % Only the gene ids
    +0150     genesInRules = setdiff(unique(genesInRules),model.genes); % Only keep new genes
    +0151 
    +0152     % If there is any gene which is not present, as to be pass as
    +0153     % newEnzymes input
    +0154     if ~isempty(genesInRules)
    +0155         errorText = 'The following genes from grRules are not present in the model, add them as newEnzymes input:';
    +0156         error('%s', ravenList(errorText,genesInRules,false))
    +0157     end
    +0158 
    +0159     % Get reversible reactions to split
    +0160     toIrrev = find(cellfun(@(x) contains(x,'<=>'),newRxns.equations));
    +0161     if ~isempty(toIrrev)
    +0162         for i=1:numel(toIrrev)
    +0163             idx = toIrrev(i);
    +0164             newEquation = split(newRxns.equations(idx),'<=>');
    +0165             % Remove directionality
    +0166             newRxns.equations(idx) = erase(newRxns.equations(idx), '<');
    +0167 
    +0168             % Add a new reaction to the list to be added
    +0169             newRxns.rxns{end+1} = [newRxns.rxns{idx} '_REV'];
    +0170             newRxns.rxnNames{end+1} = [newRxns.rxnNames{idx} ' (reversible)'];
    +0171             newRxns.equations{end+1} = [strtrim(newEquation{2, 1}) ' => ' strtrim(newEquation{1, 1})];
    +0172             newRxns.grRules{end+1} = newRxns.grRules{idx};
    +0173         end
    +0174     end
    +0175 
    +0176     % Get reactions to separate isozymes
    +0177     isozymes = cellfun(@gprToDnf, newRxns.grRules, 'UniformOutput', false);
    +0178     toSplit = find(cellfun(@numel,isozymes) > 1);
    +0179     if ~isempty(toSplit)
    +0180         splitRxns = {}; splitRxnNames = {}; splitEquations = {}; splitGrRules = {};
    +0181         for i=1:numel(toSplit)
    +0182             idx = toSplit(i);
    +0183             % One reaction per AND-clause of the gene rule in disjunctive normal form
    +0184             newRules = cellfun(@(x) strjoin(x,' and '), isozymes{idx}, 'UniformOutput', false);
    +0185 
    +0186             for j=1:numel(newRules)
    +0187                 splitRxns{end+1} = [newRxns.rxns{idx} '_EXP_' num2str(j)];
    +0188                 splitRxnNames(end+1) = newRxns.rxnNames(idx);
    +0189                 splitEquations(end+1) = newRxns.equations(idx);
    +0190                 splitGrRules(end+1) = newRules(j);
    +0191             end
    +0192         end
    +0193 
    +0194         % Remove every original that was split, in one indexed operation, then append
    +0195         % the replacements. Removing (or appending) one at a time while iterating a list
    +0196         % of indices computed up front lets each removal shift the indices of everything
    +0197         % after it, so a second (or later) original silently gets read from the wrong
    +0198         % position once more than one reaction needs splitting in the same call.
    +0199         newRxns.rxns(toSplit) = [];
    +0200         newRxns.rxnNames(toSplit) = [];
    +0201         newRxns.equations(toSplit) = [];
    +0202         newRxns.grRules(toSplit) = [];
    +0203 
    +0204         newRxns.rxns = [newRxns.rxns(:); splitRxns(:)];
    +0205         newRxns.rxnNames = [newRxns.rxnNames(:); splitRxnNames(:)];
    +0206         newRxns.equations = [newRxns.equations(:); splitEquations(:)];
    +0207         newRxns.grRules = [newRxns.grRules(:); splitGrRules(:)];
    +0208     end
    +0209 
    +0210     newRxns.lb = zeros(length(newRxns.rxns),1);
    +0211     newRxns.ub = zeros(length(newRxns.rxns),1) + 1000;
    +0212 
    +0213     model = addRxns(model, newRxns, 3, '', true, true);
    +0214 
    +0215     % 4. Add protein usage reactions.
    +0216     usageRxns.rxns            = strcat('usage_',proteinMets.mets);
    +0217     usageRxns.rxnNames        = usageRxns.rxns;
    +0218     usageRxns.mets            = cell(numel(usageRxns.rxns),1);
    +0219     usageRxns.stoichCoeffs    = cell(numel(usageRxns.rxns),1);
    +0220     for i=1:numel(usageRxns.mets)
    +0221         usageRxns.mets{i}         = {proteinMets.mets{i}, 'prot_pool'};
    +0222         usageRxns.stoichCoeffs{i} = [1,-1];
    +0223     end
    +0224     usageRxns.lb              = zeros(numel(usageRxns.rxns),1);
    +0225     usageRxns.ub              = zeros(numel(usageRxns.rxns),1) + 1000;
    +0226     usageRxns.rev             = ones(numel(usageRxns.rxns),1);
    +0227     usageRxns.grRules         = newEnzymes.genes;
    +0228     model = addRxns(model,usageRxns);
    +0229 
    +0230     % 5. Update .ec field with enzyme data
    +0231     model.ec.enzymes    = [model.ec.enzymes; newEnzymes.enzymes(:)];
    +0232     model.ec.genes      = [model.ec.genes; newEnzymes.genes(:)];
    +0233     model.ec.mw         = [model.ec.mw; newEnzymes.mw(:)];
    +0234     model.ec.sequence   = [model.ec.sequence; repmat({''},numel(newEnzymes.enzymes),1)]; 
    +0235     if isfield(model.ec,'concs')
    +0236         model.ec.concs  = [model.ec.concs; NaN(numel(newEnzymes.enzymes),1)];
    +0237     end
    +0238 
    +0239     % 6. Expand the enzyme rxns matrix
    +0240     rxnWithRule = find(~cellfun('isempty',newRxns.grRules));
    +0241 
    +0242     model.ec.rxnEnzMat =  [model.ec.rxnEnzMat, zeros(length(model.ec.rxns), length(newEnzymes.enzymes))]; % add n new enzymes
    +0243     model.ec.rxnEnzMat =  [model.ec.rxnEnzMat; zeros(length(rxnWithRule), length(model.ec.enzymes))]; % add n new rxns
    +0244 
    +0245     % 7. Update .ec field with rxn data
    +0246 
    +0247     % Get reactions to add
    +0248     numRxns = length(model.ec.rxns);
    +0249     for i = 1:numel(rxnWithRule)
    +0250         rxnIdx = rxnWithRule(i);
    +0251 
    +0252         model.ec.rxns(end+1)    = newRxns.rxns(rxnIdx);
    +0253         model.ec.kcat(end+1)    = 0;
    +0254         model.ec.source(end+1)  = {''};
    +0255         model.ec.notes(end+1)   = {''};
    +0256         model.ec.eccodes(end+1) = {''};
    +0257 
    +0258         % Get rules
    +0259         genes = regexp(newRxns.grRules{rxnIdx},'[^\s()]+','match'); % Gene ids and the word 'and', without spaces and brackets
    +0260         genes = genes(~ismember(lower(genes),{'and','or'}));
    +0261         [~,enzIdx] = ismember(genes, model.ec.genes);
    +0262 
    +0263         % Update the enzyme rxns matrix
    +0264         model.ec.rxnEnzMat(numRxns+i, enzIdx) = 1;
    +0265     end
    +0266     
    +0267     rxnsAdded = newRxns.rxns(:);
    +0268 end
    +0269 end
    +0270 
    +0271 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0272 %Function that expands a gene rule into disjunctive normal form: a cell array
    +0273 %with one cell per isozyme, each holding the gene ids that are ANDed in it.
    +0274 %Gene ids are whole words, so an id that contains 'or' or 'and' is kept
    +0275 %intact. An empty rule gives an empty cell array.
    +0276 function dnf = gprToDnf(rule)
    +0277 tokens = regexp(rule,'\(|\)|[^\s()]+','match');
    +0278 isOperator = strcmpi(tokens,'and') | strcmpi(tokens,'or');
    +0279 tokens(isOperator) = lower(tokens(isOperator)); % Operators are case insensitive
    +0280 if isempty(tokens)
    +0281     dnf = {};
    +0282     return
    +0283 end
    +0284 [dnf,pos] = parseOr(tokens,1,rule);
    +0285 if pos <= numel(tokens)
    +0286     error('Cannot parse the gene rule "%s"',rule)
    +0287 end
    +0288 end
    +0289 
    +0290 function [dnf,pos] = parseOr(tokens,pos,rule)
    +0291 [dnf,pos] = parseAnd(tokens,pos,rule);
    +0292 while pos <= numel(tokens) && strcmp(tokens{pos},'or')
    +0293     [rhs,pos] = parseAnd(tokens,pos+1,rule);
    +0294     dnf = [dnf,rhs];
    +0295 end
    +0296 end
    +0297 
    +0298 function [dnf,pos] = parseAnd(tokens,pos,rule)
    +0299 [dnf,pos] = parseAtom(tokens,pos,rule);
    +0300 while pos <= numel(tokens) && strcmp(tokens{pos},'and')
    +0301     [rhs,pos] = parseAtom(tokens,pos+1,rule);
    +0302     product = cell(1,0);
    +0303     for a = 1:numel(dnf)
    +0304         for b = 1:numel(rhs)
    +0305             product{end+1} = [dnf{a},rhs{b}]; %#ok<AGROW>
    +0306         end
    +0307     end
    +0308     dnf = product;
    +0309 end
    +0310 end
    +0311 
    +0312 function [dnf,pos] = parseAtom(tokens,pos,rule)
    +0313 if pos > numel(tokens) || any(strcmp(tokens{pos},{')','and','or'}))
    +0314     error('Cannot parse the gene rule "%s"',rule)
    +0315 elseif strcmp(tokens{pos},'(')
    +0316     [dnf,pos] = parseOr(tokens,pos+1,rule);
    +0317     if pos > numel(tokens) || ~strcmp(tokens{pos},')')
    +0318         error('Cannot parse the gene rule "%s"',rule)
    +0319     end
    +0320     pos = pos + 1;
    +0321 else
    +0322     dnf = {tokens(pos)};
    +0323     pos = pos + 1;
    +0324 end
    +0325 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/applyComplexData.html b/doc/src/change_model/applyComplexData.html new file mode 100644 index 00000000..22229c30 --- /dev/null +++ b/doc/src/change_model/applyComplexData.html @@ -0,0 +1,321 @@ + + + + Description of applyComplexData + + + + + + + + + +
    Home > src > change_model > applyComplexData.m
    + + + +

    applyComplexData +

    + +

    PURPOSE ^

    +
    applyComplexData Apply complex subunit stoichiometry to an ecModel.
    + +

    SYNOPSIS ^

    +
    function [model, foundComplex, proposedComplex] = applyComplexData(model, varargin)
    + +

    DESCRIPTION ^

    +
     applyComplexData  Apply complex subunit stoichiometry to an ecModel.
    +
    + Populates model.ec.rxnEnzMat with subunit stochiometries for protein
    + complexes, based on curated data from the EMBL-EBI Complex Portal.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + complexInfo : struct
    +     structure as generated by getComplexData. If nothing is provided, an
    +     attempt will be made to read data/ComplexPortal.json from the
    +     obj.params.path folder specified in the modelAdapter.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + verbose : logical
    +     true if a summary should be shown in the Command Window (default
    +     true).
    +
    + Returns
    + -------
    + model : struct
    +     ecModel where model.ec.rxnEnzMat is populated with subunit
    +     stochiometries.
    + foundComplex : table
    +     complexes that fully matched between the model and the complex data
    +     (columns described under Notes).
    + proposedComplex : table
    +     complexes where the model contained >75% but <100% of the proteins
    +     indicated by Complex Portal, or where the model contained more
    +     proteins than indicated for that complex in Complex Portal (same
    +     columns as foundComplex, plus a percentage match column).
    +
    + Notes
    + -----
    + The subunit stoichiometry is assigned per protein ID: the proteins of a
    + complex need not be listed in the order of model.ec.enzymes.
    +
    + foundComplex and proposedComplex share the following columns: rxn
    + (reaction identifier), complexID and name (Complex Portal identifiers),
    + genes (gene names of the complex subunits), protID_model (matched protein
    + IDs from the model), protID_complex (protein IDs listed by Complex
    + Portal), and stochiometry (subunit stoichiometry from Complex Portal).
    + proposedComplex has an additional match column with the percentage match
    + between the model proteins and the proposed complex.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     [model, foundComplex, proposedComplex] = applyComplexData(ecModel, complexInfo, modelAdapter);
    +     [model, foundComplex, proposedComplex] = applyComplexData(ecModel, 'complexInfo', complexInfo);
    +
    + See also
    + --------
    + getComplexData, makeEcModel
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • getComplexData getComplexData Download curated complex stochiometries from Complex Portal.
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function [model, foundComplex, proposedComplex] = applyComplexData(model, varargin)
    +0002 % applyComplexData  Apply complex subunit stoichiometry to an ecModel.
    +0003 %
    +0004 % Populates model.ec.rxnEnzMat with subunit stochiometries for protein
    +0005 % complexes, based on curated data from the EMBL-EBI Complex Portal.
    +0006 %
    +0007 % Parameters
    +0008 % ----------
    +0009 % model : struct
    +0010 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0011 %
    +0012 % Name-Value Arguments
    +0013 % --------------------
    +0014 % complexInfo : struct
    +0015 %     structure as generated by getComplexData. If nothing is provided, an
    +0016 %     attempt will be made to read data/ComplexPortal.json from the
    +0017 %     obj.params.path folder specified in the modelAdapter.
    +0018 % modelAdapter : ModelAdapter
    +0019 %     a loaded model adapter (default: the current default model adapter).
    +0020 % verbose : logical
    +0021 %     true if a summary should be shown in the Command Window (default
    +0022 %     true).
    +0023 %
    +0024 % Returns
    +0025 % -------
    +0026 % model : struct
    +0027 %     ecModel where model.ec.rxnEnzMat is populated with subunit
    +0028 %     stochiometries.
    +0029 % foundComplex : table
    +0030 %     complexes that fully matched between the model and the complex data
    +0031 %     (columns described under Notes).
    +0032 % proposedComplex : table
    +0033 %     complexes where the model contained >75% but <100% of the proteins
    +0034 %     indicated by Complex Portal, or where the model contained more
    +0035 %     proteins than indicated for that complex in Complex Portal (same
    +0036 %     columns as foundComplex, plus a percentage match column).
    +0037 %
    +0038 % Notes
    +0039 % -----
    +0040 % The subunit stoichiometry is assigned per protein ID: the proteins of a
    +0041 % complex need not be listed in the order of model.ec.enzymes.
    +0042 %
    +0043 % foundComplex and proposedComplex share the following columns: rxn
    +0044 % (reaction identifier), complexID and name (Complex Portal identifiers),
    +0045 % genes (gene names of the complex subunits), protID_model (matched protein
    +0046 % IDs from the model), protID_complex (protein IDs listed by Complex
    +0047 % Portal), and stochiometry (subunit stoichiometry from Complex Portal).
    +0048 % proposedComplex has an additional match column with the percentage match
    +0049 % between the model proteins and the proposed complex.
    +0050 %
    +0051 % Examples
    +0052 % --------
    +0053 %     % optional arguments may be given positionally or as name-value pairs:
    +0054 %     [model, foundComplex, proposedComplex] = applyComplexData(ecModel, complexInfo, modelAdapter);
    +0055 %     [model, foundComplex, proposedComplex] = applyComplexData(ecModel, 'complexInfo', complexInfo);
    +0056 %
    +0057 % See also
    +0058 % --------
    +0059 % getComplexData, makeEcModel
    +0060 
    +0061 p = parseGECKOargs(varargin, { ...
    +0062     'complexInfo',  []; ...
    +0063     'modelAdapter', []; ...
    +0064     'verbose',      true});
    +0065 complexInfo  = p.complexInfo;
    +0066 modelAdapter = p.modelAdapter;
    +0067 verbose      = p.verbose;
    +0068 if isempty(verbose); verbose = true; end
    +0069 
    +0070 if isempty(modelAdapter)
    +0071     modelAdapter = ModelAdapterManager.getDefault();
    +0072     if isempty(modelAdapter)
    +0073         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0074     end
    +0075 end
    +0076 params = modelAdapter.params;
    +0077 
    +0078 if isempty(complexInfo)
    +0079     complexInfo = fullfile(params.path,'data','ComplexPortal.json');
    +0080     if ~isfile(complexInfo)
    +0081         complexInfo = getComplexData([], modelAdapter);
    +0082     end
    +0083 end
    +0084 
    +0085 if ischar(complexInfo) || isstring(complexInfo)
    +0086     jsonStr = fileread(complexInfo);
    +0087     complexData = jsondecode(jsonStr);
    +0088 else
    +0089     complexData = complexInfo;
    +0090 end
    +0091 
    +0092 %Remove prefixes on rxn names for gecko light
    +0093 if ~model.ec.geckoLight
    +0094     rxnNames = model.ec.rxns;
    +0095 else
    +0096     rxnNames = extractAfter(model.ec.rxns,4);
    +0097 end
    +0098 
    +0099 foundComplex = cell(numel(rxnNames),7);
    +0100 foundComplexCount = 0;
    +0101 proposedComplex = cell(numel(rxnNames)*2,8); % Might propose more
    +0102 proposedComplexCount = 0;
    +0103 
    +0104 complexProts = repmat({''}, numel({complexData.complexID})*10, 1);
    +0105 complexMatrix = zeros(numel({complexData.complexID}),numel(complexProts));
    +0106 lastProt = 0;
    +0107 for i=1:size(complexMatrix,1)
    +0108     % Locate proteins (and add if new)
    +0109     protIDs     = complexData(i).protID;
    +0110     [isOld, protMatIdx] = ismember(protIDs,complexProts);
    +0111     newProts    = protIDs(~isOld);
    +0112     complexProts(lastProt+1:lastProt+numel(newProts))=newProts;
    +0113     protMatIdx(~isOld)  = lastProt+1 : lastProt+numel(newProts);
    +0114     lastProt = lastProt + numel(newProts);
    +0115     % Add subunit numbers
    +0116     if all(complexData(i).stochiometry == 0)
    +0117         complexData(i).stochiometry(:) = 1;
    +0118     end
    +0119     complexMatrix(i,protMatIdx) = complexData(i).stochiometry;
    +0120 end
    +0121 
    +0122 % Remove excess space
    +0123 complexMatrix(:,lastProt+1:end) = [];
    +0124 complexProts(lastProt+1:end) = [];
    +0125 PB = progressReport(numel(rxnNames), 'Assign complexes to reactions');
    +0126 for i = 1:numel(rxnNames)
    +0127     PB.count;
    +0128     % Get the proteins from the model
    +0129     modelProts = model.ec.enzymes(find(model.ec.rxnEnzMat(i,:)));
    +0130     [protsInMat, protsIdx] = ismember(modelProts,complexProts);
    +0131     if ~any(protsInMat)
    +0132         continue
    +0133     end
    +0134     % Find complexes that includes the model proteins
    +0135     [potComplex,~] = find(complexMatrix(:,protsIdx(protsInMat)));
    +0136     potComplex = unique(potComplex);
    +0137     % Some stats on number of subunits, percentage match etc.
    +0138     matchComplexUnits = sum(logical(complexMatrix(potComplex,protsIdx(protsInMat))),2);
    +0139     totalComplexUnits = sum(logical(complexMatrix(potComplex,:)),2);
    +0140     modComplexUnits = numel(modelProts);
    +0141     percMatch  = matchComplexUnits/modComplexUnits;
    +0142     totalMatch = totalComplexUnits/modComplexUnits;
    +0143     if any(percMatch == 1 & totalMatch == 1)
    +0144         % Exact match
    +0145         complexMatch = find(percMatch == 1 & totalMatch == 1);
    +0146         if numel(complexMatch)>1 % If more than one match, take first match
    +0147             complexMatch = complexMatch(1);
    +0148         end
    +0149         complexMatch = potComplex(complexMatch);
    +0150         foundComplexCount = foundComplexCount + 1;
    +0151         foundComplex{foundComplexCount,1} = model.ec.rxns{i};
    +0152         foundComplex{foundComplexCount,2} = complexData(complexMatch).complexID;
    +0153         foundComplex{foundComplexCount,3} = complexData(complexMatch).name;
    +0154         foundComplex{foundComplexCount,4} = complexData(complexMatch).geneName;
    +0155         foundComplex{foundComplexCount,5} = modelProts;
    +0156         foundComplex{foundComplexCount,6} = complexData(complexMatch).protID;
    +0157         foundComplex{foundComplexCount,7} = complexData(complexMatch).stochiometry;
    +0158 
    +0159         % Apply in rxnEnzMat
    +0160         % The stoichiometry is taken per protein ID, as the proteins of the
    +0161         % complex need not be listed in the order of model.ec.enzymes
    +0162         [~, modelProtsIdx] = ismember(modelProts, model.ec.enzymes);
    +0163         [~, complexPos] = ismember(modelProts, complexData(complexMatch).protID);
    +0164         model.ec.rxnEnzMat(i,modelProtsIdx) = complexData(complexMatch).stochiometry(complexPos);
    +0165     
    +0166     elseif modComplexUnits > 1 % Only suggest potential complex if grRule > 1 protein
    +0167         moreUnitsInData = find(percMatch == 1 & totalMatch > 1);
    +0168         if any(moreUnitsInData)
    +0169             % All ecModel subunits match, but Complex Portal has more subunits
    +0170             % Take the complex with the minimum number of extra subunits
    +0171             [~,propComplex] = min(totalMatch(moreUnitsInData));
    +0172             propComplex     = moreUnitsInData(propComplex);
    +0173             selectComplex   = potComplex(propComplex);
    +0174             proposedComplexCount = proposedComplexCount + 1;
    +0175             proposedComplex{proposedComplexCount,1} = model.ec.rxns{i};
    +0176             proposedComplex{proposedComplexCount,2} = complexData(selectComplex).complexID;
    +0177             proposedComplex{proposedComplexCount,3} = complexData(selectComplex).name;
    +0178             proposedComplex{proposedComplexCount,4} = complexData(selectComplex).geneName;
    +0179             proposedComplex{proposedComplexCount,5} = modelProts;
    +0180             proposedComplex{proposedComplexCount,6} = complexData(selectComplex).protID;
    +0181             proposedComplex{proposedComplexCount,7} = complexData(selectComplex).stochiometry;
    +0182             proposedComplex{proposedComplexCount,8} = totalMatch(propComplex)*100;
    +0183         end
    +0184         otherUnits = find(percMatch >= 0.75 & percMatch < 1 & totalMatch <= 1);
    +0185         if any(otherUnits)
    +0186             % At least 75% of ecModels subunits match, Complex Portal maybe have less or different subunits
    +0187             % Take the complex with highest % match.
    +0188             [~,propComplex] = max(percMatch(otherUnits));
    +0189             propComplex     = otherUnits(propComplex);
    +0190             selectComplex   = potComplex(propComplex);
    +0191             proposedComplexCount = proposedComplexCount + 1;
    +0192             proposedComplex{proposedComplexCount,1} = model.ec.rxns{i};
    +0193             proposedComplex{proposedComplexCount,2} = complexData(selectComplex).complexID;
    +0194             proposedComplex{proposedComplexCount,3} = complexData(selectComplex).name;
    +0195             proposedComplex{proposedComplexCount,4} = complexData(selectComplex).geneName;
    +0196             proposedComplex{proposedComplexCount,5} = modelProts;
    +0197             proposedComplex{proposedComplexCount,6} = complexData(selectComplex).protID;
    +0198             proposedComplex{proposedComplexCount,7} = complexData(selectComplex).stochiometry;
    +0199             proposedComplex{proposedComplexCount,8} = percMatch(propComplex)*100;
    +0200         end
    +0201     end
    +0202 end
    +0203 PB.done;
    +0204 
    +0205 % Remove empty space
    +0206 foundComplex(foundComplexCount+1:end,:) = [];
    +0207 proposedComplex(proposedComplexCount+1:end,:) = [];
    +0208 
    +0209 rowHeadings = {'rxn', 'complexID','name','genes','protID_model','protID_complex','stochiometry'};
    +0210 
    +0211 foundComplex = cell2table(foundComplex, 'VariableNames', rowHeadings);
    +0212 
    +0213 proposedComplex = cell2table(proposedComplex, 'VariableNames', [rowHeadings 'match']);
    +0214 if verbose
    +0215     disp(['A total of ' int2str(numel(foundComplex(:,1))) ' complex have full match, and ' int2str(numel(proposedComplex(:,1))) ' proposed.'])
    +0216 end
    +0217 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/applyCustomKcats.html b/doc/src/change_model/applyCustomKcats.html new file mode 100644 index 00000000..4d23acea --- /dev/null +++ b/doc/src/change_model/applyCustomKcats.html @@ -0,0 +1,394 @@ + + + + Description of applyCustomKcats + + + + + + + + + +
    Home > src > change_model > applyCustomKcats.m
    + + + +

    applyCustomKcats +

    + +

    PURPOSE ^

    +
    applyCustomKcats Apply user-defined kcats to an ecModel.
    + +

    SYNOPSIS ^

    +
    function [model, rxnUpdated, notMatch] = applyCustomKcats(model, varargin)
    + +

    DESCRIPTION ^

    +
     applyCustomKcats  Apply user-defined kcats to an ecModel.
    +
    + Reads data/customKcats.tsv in the obj.params.path specified in the model
    + adapter. Alternatively, a customKcats structure can be provided, as
    + specified below.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + customKcats : struct
    +     structure with custom kcat information (fields described under Notes).
    +     If nothing is provided, an attempt will be made to read
    +     data/customKcats.tsv from the obj.params.path folder specified in the
    +     modelAdapter.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + model : struct
    +     ecModel where kcats for defined proteins have been changed.
    + rxnUpdated : cell
    +     ids list of updated reactions, where new kcats were applied.
    + notMatch : table
    +     reactions for which the custom information provided has a partial
    +     match (at least 50%, but not 100%) with the reaction's GPR rule, for
    +     the user to curate manually. Columns: rxns and name (reaction
    +     identifier and name), custom enzymes (the proteins specified in
    +     customKcats), enzymes in model (the enzymes annotated to the reaction
    +     in the model), and rules (the reaction's GPR rule).
    +
    + Notes
    + -----
    + The customKcats structure has the following fields:
    +
    + - proteins : protein identifiers, multiple for the same kcat (in case of a protein complex) are separated by ' + '.
    + - genes : gene identifiers (optional, not used in matching).
    + - gene_name : short gene name (optional, not used in matching).
    + - kcat : new kcat value (one per entry).
    + - rxns : reaction identifiers, multiple for the same kcat are separated by ',' (see further explanation below).
    + - notes : will be appended to model.ec.notes, separated by ', ' from an existing note; an empty note changes nothing (optional).
    + - stoicho : complex stoichiometry, separated by ' + ' (examples: '1' or '3 + 1'), matching the order in proteins field.
    +
    + An entry with an empty kcat is skipped. Protein and reaction identifiers
    + are matched exactly, including their letter case. Light ecModels are
    + supported: the rows of model.ec are matched by their ec reaction ids.
    +
    + Matching order:
    +
    + 1. reactions are identified by .proteins and .rxns.
    + 2. reactions are identified by .proteins only (empty .rxns entry); no
    +    additional checks are made: is a reaction annotated with these
    +    proteins? => its kcat will be updated, irrespective of the exact
    +    reaction, direction, substrate, etc.
    + 3. reactions are identified by .rxns only (empty .proteins entry); no
    +    additional checks are made: is a reaction derived from the original
    +    reaction identifier => its kcat will be updated, irrespective of the
    +    annotated protein.
    +
    + The customKcats.rxns field reaction identifiers are from the ORIGINAL
    + model, before _EXP_ suffixes were added by makeEcModel. Reaction
    + directionality IS however specified, with a _REV suffix. Example entries:
    +
    + - 'r_0001' will match r_0001, r_0001_EXP_1, r_0001_EXP_2 etc., but not r_0001_REV, r_0001_EXP_1_REV etc.
    + - 'r_0001_REV' will match r_0001_REV, r_0001_EXP_1_REV, r_0001_EXP_2_REV, etc., but not r_0001, r_0001_EXP_1 etc.
    +
    + Multiple identifiers should be comma separated (e.g. r_0001, r_0002).
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     [model, rxnUpdated, notMatch] = applyCustomKcats(model, customKcats, modelAdapter);
    +     [model, rxnUpdated, notMatch] = applyCustomKcats(model, 'customKcats', customKcats);
    +
    + See also
    + --------
    + applyKcatConstraints, makeEcModel
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: + +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [model, rxnUpdated, notMatch] = applyCustomKcats(model, varargin)
    +0002 % applyCustomKcats  Apply user-defined kcats to an ecModel.
    +0003 %
    +0004 % Reads data/customKcats.tsv in the obj.params.path specified in the model
    +0005 % adapter. Alternatively, a customKcats structure can be provided, as
    +0006 % specified below.
    +0007 %
    +0008 % Parameters
    +0009 % ----------
    +0010 % model : struct
    +0011 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0012 %
    +0013 % Name-Value Arguments
    +0014 % --------------------
    +0015 % customKcats : struct
    +0016 %     structure with custom kcat information (fields described under Notes).
    +0017 %     If nothing is provided, an attempt will be made to read
    +0018 %     data/customKcats.tsv from the obj.params.path folder specified in the
    +0019 %     modelAdapter.
    +0020 % modelAdapter : ModelAdapter
    +0021 %     a loaded model adapter (default: the current default model adapter).
    +0022 %
    +0023 % Returns
    +0024 % -------
    +0025 % model : struct
    +0026 %     ecModel where kcats for defined proteins have been changed.
    +0027 % rxnUpdated : cell
    +0028 %     ids list of updated reactions, where new kcats were applied.
    +0029 % notMatch : table
    +0030 %     reactions for which the custom information provided has a partial
    +0031 %     match (at least 50%, but not 100%) with the reaction's GPR rule, for
    +0032 %     the user to curate manually. Columns: rxns and name (reaction
    +0033 %     identifier and name), custom enzymes (the proteins specified in
    +0034 %     customKcats), enzymes in model (the enzymes annotated to the reaction
    +0035 %     in the model), and rules (the reaction's GPR rule).
    +0036 %
    +0037 % Notes
    +0038 % -----
    +0039 % The customKcats structure has the following fields:
    +0040 %
    +0041 % - proteins : protein identifiers, multiple for the same kcat (in case of a protein complex) are separated by ' + '.
    +0042 % - genes : gene identifiers (optional, not used in matching).
    +0043 % - gene_name : short gene name (optional, not used in matching).
    +0044 % - kcat : new kcat value (one per entry).
    +0045 % - rxns : reaction identifiers, multiple for the same kcat are separated by ',' (see further explanation below).
    +0046 % - notes : will be appended to model.ec.notes, separated by ', ' from an existing note; an empty note changes nothing (optional).
    +0047 % - stoicho : complex stoichiometry, separated by ' + ' (examples: '1' or '3 + 1'), matching the order in proteins field.
    +0048 %
    +0049 % An entry with an empty kcat is skipped. Protein and reaction identifiers
    +0050 % are matched exactly, including their letter case. Light ecModels are
    +0051 % supported: the rows of model.ec are matched by their ec reaction ids.
    +0052 %
    +0053 % Matching order:
    +0054 %
    +0055 % 1. reactions are identified by .proteins and .rxns.
    +0056 % 2. reactions are identified by .proteins only (empty .rxns entry); no
    +0057 %    additional checks are made: is a reaction annotated with these
    +0058 %    proteins? => its kcat will be updated, irrespective of the exact
    +0059 %    reaction, direction, substrate, etc.
    +0060 % 3. reactions are identified by .rxns only (empty .proteins entry); no
    +0061 %    additional checks are made: is a reaction derived from the original
    +0062 %    reaction identifier => its kcat will be updated, irrespective of the
    +0063 %    annotated protein.
    +0064 %
    +0065 % The customKcats.rxns field reaction identifiers are from the ORIGINAL
    +0066 % model, before _EXP_ suffixes were added by makeEcModel. Reaction
    +0067 % directionality IS however specified, with a _REV suffix. Example entries:
    +0068 %
    +0069 % - 'r_0001' will match r_0001, r_0001_EXP_1, r_0001_EXP_2 etc., but not r_0001_REV, r_0001_EXP_1_REV etc.
    +0070 % - 'r_0001_REV' will match r_0001_REV, r_0001_EXP_1_REV, r_0001_EXP_2_REV, etc., but not r_0001, r_0001_EXP_1 etc.
    +0071 %
    +0072 % Multiple identifiers should be comma separated (e.g. r_0001, r_0002).
    +0073 %
    +0074 % Examples
    +0075 % --------
    +0076 %     % optional arguments may be given positionally or as name-value pairs:
    +0077 %     [model, rxnUpdated, notMatch] = applyCustomKcats(model, customKcats, modelAdapter);
    +0078 %     [model, rxnUpdated, notMatch] = applyCustomKcats(model, 'customKcats', customKcats);
    +0079 %
    +0080 % See also
    +0081 % --------
    +0082 % applyKcatConstraints, makeEcModel
    +0083 
    +0084 p = parseGECKOargs(varargin, { ...
    +0085     'customKcats',  []; ...
    +0086     'modelAdapter', []});
    +0087 customKcats  = p.customKcats;
    +0088 modelAdapter = p.modelAdapter;
    +0089 
    +0090 if isempty(modelAdapter)
    +0091     modelAdapter = ModelAdapterManager.getDefault();
    +0092     if isempty(modelAdapter)
    +0093         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0094     end
    +0095 end
    +0096 
    +0097 params = modelAdapter.params;
    +0098 
    +0099 if isempty(customKcats)
    +0100     customKcats = fullfile(params.path,'data','customKcats.tsv');
    +0101 end
    +0102 if isstruct(customKcats)
    +0103     if ~all(isfield(customKcats,{'proteins','kcat','rxns'}))
    +0104         error('The customKcats structure does not have all essential fields.');
    +0105     end
    +0106 elseif isfile(customKcats)
    +0107     fID = fopen(customKcats, 'r');
    +0108     fileContent = textscan(fID, '%s %s %s %f %q %s %s', 'Delimiter', '\t', 'HeaderLines', 1);
    +0109     fclose(fID);
    +0110     clear customKcats
    +0111     customKcats.proteins    = fileContent{1};
    +0112     customKcats.genes       = fileContent{2};
    +0113     customKcats.gene_name   = fileContent{3};
    +0114     customKcats.kcat        = fileContent{4};
    +0115     customKcats.rxns        = fileContent{5};
    +0116     customKcats.notes       = fileContent{6};
    +0117     customKcats.stoicho     = fileContent{7};
    +0118 else
    +0119     error(['Cannot find file: ' customKcats]);
    +0120 end
    +0121 
    +0122 rxnToUpdate = false(length(model.ec.rxns),1);
    +0123 rxnNotMatch = false(length(model.ec.rxns),1);
    +0124 evaluatedRule = cell(length(model.ec.rxns),1);
    +0125 enzInModel = cell(length(model.ec.rxns),1);
    +0126 ecRxnNoSuffix = regexprep(model.ec.rxns,'_EXP_\d+$','');
    +0127 
    +0128 for i = 1:numel(customKcats.proteins)
    +0129     if isnan(customKcats.kcat(i))
    +0130         printOrange(['WARNING: Entry ' num2str(i) ' has no kcat; it is skipped.']);
    +0131         continue
    +0132     end
    +0133     if isempty(customKcats.proteins{i})
    +0134         %If only reaction ID(s) is/are specified (and no proteins),
    +0135         %then apply the kcat to all isozymic reactions
    +0136         rxns    = strtrim(strsplit(customKcats.rxns{i}, ','));
    +0137         rxnIdxs = ismember(ecRxnNoSuffix,rxns);
    +0138         rxnToUpdate(rxnIdxs) = 1;
    +0139         model.ec.kcat(rxnIdxs) = customKcats.kcat(i);
    +0140 
    +0141         % Add note mentioning manual kcat change
    +0142         model.ec.source(rxnIdxs) = {'custom'};
    +0143         if isfield(customKcats,'notes')
    +0144             matchedIdxs = find(rxnIdxs);
    +0145             for j = 1:numel(matchedIdxs)
    +0146                 model.ec.notes{matchedIdxs(j), 1} = appendNote(model.ec.notes{matchedIdxs(j), 1}, customKcats.notes{i});
    +0147             end
    +0148         end
    +0149     else
    +0150         prots = strtrim(strsplit(customKcats.proteins{i}, '+'));
    +0151 
    +0152         % Find the index for the enzymes which kcat will be changed. In
    +0153         % case the protein is not in the model generate a warning.
    +0154         try
    +0155             enzIdx = cellfun(@(x) find(strcmp(model.ec.enzymes, x)), prots);
    +0156         catch
    +0157             enzIdx = [];
    +0158             printOrange(['WARNING: Protein(s) ' customKcats.proteins{i} ' were not found in the model.']);
    +0159         end
    +0160 
    +0161         % if not specific reactions are defined, find all the reaction
    +0162         % index where the enzyme is used
    +0163         if isempty(customKcats.rxns{i})
    +0164             temp_rxnIdxs = arrayfun(@(x) find(model.ec.rxnEnzMat(:, x)), enzIdx, 'UniformOutput', false);
    +0165             % otherwhise, If a set of reactions if defined, only get the index for those
    +0166             % but ignore any _EXP_ suffixes
    +0167         else
    +0168             rxns = strtrim(strsplit(customKcats.rxns{i}, ','));
    +0169             temp_rxnIdxs = cellfun(@(x) find(strcmp(ecRxnNoSuffix, x)), rxns, 'UniformOutput', false);
    +0170         end
    +0171 
    +0172         if ~isempty(temp_rxnIdxs)
    +0173             rxnIdxs = [];
    +0174             for j = 1:numel(temp_rxnIdxs)
    +0175                 rxnIdxs = [rxnIdxs; temp_rxnIdxs{j}];
    +0176             end
    +0177 
    +0178             % Check when multiple proteins are involved, since it can return same rxn n times
    +0179             rxnIdxs = unique(rxnIdxs); %unique(rxnIdxs{1, :});
    +0180 
    +0181             for j = 1:numel(rxnIdxs)
    +0182                 % Get all the enzymes involved in the reaction
    +0183                 allEnzInRxn = find(model.ec.rxnEnzMat(rxnIdxs(j),:));
    +0184 
    +0185                 C = intersect(enzIdx, allEnzInRxn);
    +0186 
    +0187                 % Determine the match percentage bewteen the rules
    +0188                 if numel(C) == numel(enzIdx) && numel(C) == numel(allEnzInRxn)
    +0189                     match = 1;
    +0190                 else
    +0191                     if numel(enzIdx) < numel(allEnzInRxn)
    +0192                         match = numel(C) / numel(allEnzInRxn);
    +0193                     else
    +0194                         match = numel(C) / numel(enzIdx);
    +0195                     end
    +0196                 end
    +0197 
    +0198                 % Update the kcat value stored in the model, if match 100%,
    +0199                 % otherwhise if >= 0.5 inform to the user to be validated
    +0200                 if match == 1
    +0201                     rxnToUpdate(rxnIdxs(j)) = 1;
    +0202                     model.ec.kcat(rxnIdxs(j)) = customKcats.kcat(i);
    +0203 
    +0204                     % Add note mentioning manual kcat change
    +0205                     model.ec.source{rxnIdxs(j),1} = 'custom';
    +0206                     if isfield(customKcats,'notes')
    +0207                         model.ec.notes{rxnIdxs(j), 1} = appendNote(model.ec.notes{rxnIdxs(j), 1}, customKcats.notes{i});
    +0208                     end
    +0209                 elseif match >= 0.5 && match < 1
    +0210                     rxnNotMatch(rxnIdxs(j)) = 1;
    +0211                     evaluatedRule{rxnIdxs(j), 1} = customKcats.proteins{i};
    +0212                     enzInModel{rxnIdxs(j), 1} = strjoin(model.ec.enzymes(allEnzInRxn), ' + ');
    +0213                 end
    +0214             end
    +0215         end
    +0216     end
    +0217 end
    +0218 
    +0219 % Apply the new kcat values to the model
    +0220 if ~isempty(find(rxnToUpdate, 1))
    +0221     if model.ec.geckoLight
    +0222         %Light ecModels update by reaction of the model, not by ec row
    +0223         updateRxns = ismember(model.rxns, extractAfter(model.ec.rxns(rxnToUpdate), 4));
    +0224     else
    +0225         updateRxns = rxnToUpdate;
    +0226     end
    +0227     model = applyKcatConstraints(model, updateRxns);
    +0228 else
    +0229     printOrange('WARNING: No matches found. Consider checking the IDs or proteins in customKcats.');
    +0230 end
    +0231 
    +0232 rxnUpdated = model.ec.rxns(find(rxnToUpdate));
    +0233 
    +0234 % Remove from notMatch those reactions already updated
    +0235 remove = and(rxnToUpdate, rxnNotMatch);
    +0236 rxnNotMatch(remove) = 0;
    +0237 evaluatedRule(remove) = '';
    +0238 enzInModel(remove) = '';
    +0239 
    +0240 idRxns = model.ec.rxns(find(rxnNotMatch));
    +0241 if model.ec.geckoLight
    +0242     modelRxnIds = extractAfter(idRxns, 4);
    +0243 else
    +0244     modelRxnIds = idRxns;
    +0245 end
    +0246 fullIdx = cellfun(@(x) find(strcmpi(model.rxns, x), 1), modelRxnIds);
    +0247 rxnsNames = model.rxnNames(fullIdx);
    +0248 evaluatedRule = evaluatedRule(~cellfun('isempty', evaluatedRule));
    +0249 enzInModel = enzInModel(~cellfun('isempty', enzInModel));
    +0250 rules = model.grRules(fullIdx);
    +0251 notMatch = table(idRxns, rxnsNames, evaluatedRule, enzInModel, rules, ...
    +0252     'VariableNames',{'rxns', 'name', 'custom enzymes', 'enzymes in model', 'rules'});
    +0253 end
    +0254 
    +0255 function notes = appendNote(notes, note)
    +0256 % An empty note changes nothing; a note is separated by ', ' from an existing one.
    +0257 note = strtrim(note);
    +0258 if isempty(note)
    +0259     return
    +0260 elseif isempty(notes)
    +0261     notes = note;
    +0262 else
    +0263     notes = [notes ', ' note];
    +0264 end
    +0265 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/applyKcatConstraints.html b/doc/src/change_model/applyKcatConstraints.html new file mode 100644 index 00000000..b9264430 --- /dev/null +++ b/doc/src/change_model/applyKcatConstraints.html @@ -0,0 +1,249 @@ + + + + Description of applyKcatConstraints + + + + + + + + + +
    Home > src > change_model > applyKcatConstraints.m
    + + + +

    applyKcatConstraints +

    + +

    PURPOSE ^

    +
    applyKcatConstraints Apply kcat-derived enzyme constraints to an ecModel.
    + +

    SYNOPSIS ^

    +
    function model = applyKcatConstraints(model,varargin)
    + +

    DESCRIPTION ^

    +
     applyKcatConstraints  Apply kcat-derived enzyme constraints to an ecModel.
    +
    + Existing enzyme constraints are first removed (unless updateRxns is
    + provided), and new constraints are defined based on the content of
    + model.ec.kcat. When every kcat is 0, the existing constraints of a full
    + ecModel are removed and no new ones are written; a light ecModel is
    + returned unchanged.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + updateRxns : logical or double or cell or char or string
    +     if not all enzyme constraints should be updated, this can be given as
    +     either a logical vector of length model.ec.rxns, a vector of
    +     model.ec.rxns indices, or a (cell array of) string(s) with
    +     model.ec.rxns identifiers. For light models, these reactions should
    +     match model.rxns.
    +
    + Returns
    + -------
    + model : struct
    +     ecModel where reactions are constrained by enzyme usage if a kcat
    +     value was provided for the reaction-enzyme pair in model.ec.kcat.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     model = applyKcatConstraints(model, updateRxns);
    +     model = applyKcatConstraints(model, 'updateRxns', updateRxns);
    +
    + See also
    + --------
    + makeEcModel, getKcatAcrossIsozymes, setKcatForReactions
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: + + + + + +

    SOURCE CODE ^

    +
    0001 function model = applyKcatConstraints(model,varargin)
    +0002 % applyKcatConstraints  Apply kcat-derived enzyme constraints to an ecModel.
    +0003 %
    +0004 % Existing enzyme constraints are first removed (unless updateRxns is
    +0005 % provided), and new constraints are defined based on the content of
    +0006 % model.ec.kcat. When every kcat is 0, the existing constraints of a full
    +0007 % ecModel are removed and no new ones are written; a light ecModel is
    +0008 % returned unchanged.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % model : struct
    +0013 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0014 %
    +0015 % Name-Value Arguments
    +0016 % --------------------
    +0017 % updateRxns : logical or double or cell or char or string
    +0018 %     if not all enzyme constraints should be updated, this can be given as
    +0019 %     either a logical vector of length model.ec.rxns, a vector of
    +0020 %     model.ec.rxns indices, or a (cell array of) string(s) with
    +0021 %     model.ec.rxns identifiers. For light models, these reactions should
    +0022 %     match model.rxns.
    +0023 %
    +0024 % Returns
    +0025 % -------
    +0026 % model : struct
    +0027 %     ecModel where reactions are constrained by enzyme usage if a kcat
    +0028 %     value was provided for the reaction-enzyme pair in model.ec.kcat.
    +0029 %
    +0030 % Examples
    +0031 % --------
    +0032 %     % optional arguments may be given positionally or as name-value pairs:
    +0033 %     model = applyKcatConstraints(model, updateRxns);
    +0034 %     model = applyKcatConstraints(model, 'updateRxns', updateRxns);
    +0035 %
    +0036 % See also
    +0037 % --------
    +0038 % makeEcModel, getKcatAcrossIsozymes, setKcatForReactions
    +0039 
    +0040 p = parseGECKOargs(varargin, { ...
    +0041     'updateRxns', []});
    +0042 updateRxns = p.updateRxns;
    +0043 
    +0044 %these lines are for the updateRxns handling below only
    +0045 if (model.ec.geckoLight)
    +0046     rxns = model.rxns;
    +0047 else
    +0048     rxns = model.ec.rxns;
    +0049 end
    +0050 
    +0051 if isempty(updateRxns)
    +0052     updateRxns = true(numel(rxns),1);
    +0053 elseif isnumeric(updateRxns)
    +0054     updateRxnsLog = false(numel(rxns),1);
    +0055     updateRxnsLog(updateRxns) = true;
    +0056     updateRxns = updateRxnsLog;
    +0057 elseif iscellstr(updateRxns) || ischar(updateRxns) || isstring(updateRxns)
    +0058     updateRxnsIds = convertCharArray(updateRxns);
    +0059     updateRxns = ismember(rxns,updateRxnsIds);
    +0060 end
    +0061  
    +0062 if isempty(find(updateRxns, 1)) || isempty(updateRxns)
    +0063      error('No reaction to update or updateRxns is logical but without any true value')
    +0064 end
    +0065 
    +0066 if ~isfield(model,'ec')
    +0067     error(['No model.ec structure could be found: the provided model is'...
    +0068            ' not a valid GECKO3 ecModel. First run makeEcModel(model).'])
    +0069 end
    +0070 if all(model.ec.kcat==0)
    +0071     if model.ec.geckoLight
    +0072         printOrange('WARNING: No kcat values are provided in model.ec.kcat, model remains unchanged.\n');
    +0073         return
    +0074     end
    +0075     % In a full model the existing enzyme constraints of the selected
    +0076     % reactions are still cleared below, and no new ones are written.
    +0077     printOrange('WARNING: No kcat values are provided in model.ec.kcat, existing enzyme constraints are cleared and no new ones are written.\n');
    +0078 end
    +0079 
    +0080 %Clear existing incorporation of enzyme usage
    +0081 if ~model.ec.geckoLight
    +0082     protMetIdx = startsWith(model.mets,'prot_') & ~strcmp(model.mets,'prot_pool');
    +0083     metabolRxn = unique(model.ec.rxns(updateRxns));
    +0084     metabolRxn = ismember(model.rxns,metabolRxn);
    +0085     model.S(protMetIdx,metabolRxn) = 0;
    +0086 end %no clearing needed for GECKO Light, will be overwritten below
    +0087 %For normal GECKO formulation (full model), where each enzyme is explicitly considered
    +0088 if ~model.ec.geckoLight 
    +0089     %Column 1 = rxn idx; 2 = enzyme idx; 3 = subunit copies; 4 = kcat; 5 = MW
    +0090     newKcats=zeros(numel(updateRxns)*10,5);
    +0091     updateRxns=find(updateRxns);
    +0092     kcatFirst=0;
    +0093     for i=1:numel(updateRxns)
    +0094         j=updateRxns(i);
    +0095         if model.ec.kcat(j) ~= 0
    +0096             enzymes   = find(model.ec.rxnEnzMat(j,:));
    +0097             kcatLast  = kcatFirst+numel(enzymes);
    +0098             kcatFirst = kcatFirst+1;
    +0099             newKcats(kcatFirst:kcatLast,1) = j;
    +0100             newKcats(kcatFirst:kcatLast,2) = enzymes;
    +0101             newKcats(kcatFirst:kcatLast,3) = model.ec.rxnEnzMat(j,enzymes);
    +0102             newKcats(kcatFirst:kcatLast,4) = model.ec.kcat(j);
    +0103             newKcats(kcatFirst:kcatLast,5) = model.ec.mw(enzymes);
    +0104             kcatFirst = kcatLast;
    +0105         end
    +0106     end
    +0107     if exist('kcatLast','var') % If it does not, then no kcats are found
    +0108         newKcats(kcatLast+1:end,:)=[];
    +0109 
    +0110         sel = newKcats(:,4) > 0; %Only apply to non-zero kcat
    +0111         newKcats(sel,4) = newKcats(sel,4) * 3600; %per second -> per hour
    +0112         newKcats(sel,4) = newKcats(sel,5) ./ newKcats(sel,4); %MW/kcat
    +0113         newKcats(sel,4) = newKcats(sel,3) .* newKcats(sel,4); %Multicopy subunits.
    +0114         newKcats(~sel,4) = 0; %Results in zero-cost
    +0115 
    +0116         %Replace rxns and enzymes with their location in model
    +0117         [~,newKcats(:,1)] = ismember(model.ec.rxns(newKcats(:,1)),model.rxns);
    +0118         [~,newKcats(:,2)] = ismember(strcat('prot_',model.ec.enzymes(newKcats(:,2))),model.mets);
    +0119         linearIndices     = sub2ind(size(model.S),newKcats(:,2),newKcats(:,1));
    +0120         %Two enzyme rows can map to the same prot_<accession> metabolite (distinct
    +0121         %genes sharing one UniProt entry), giving a repeated linear index here. A
    +0122         %plain indexed assignment on a repeated index keeps only the last value
    +0123         %written, silently dropping the other enzyme's contribution instead of
    +0124         %adding it, so accumulate per unique index instead.
    +0125         [uniqueIndices,~,linearIndicesToUnique] = unique(linearIndices);
    +0126         summedValues = accumarray(linearIndicesToUnique,-newKcats(:,4));
    +0127         model.S(uniqueIndices) = summedValues; %Substrate = negative
    +0128     end
    +0129 else %GECKO light formulation, where prot_pool represents all usages
    +0130     prot_pool_idx = find(ismember(model.mets,'prot_pool'));
    +0131     %first remove the prefix of all rxns
    +0132     modRxns     = extractAfter(model.ec.rxns,4);
    +0133     % Map ec-reactions to model.rxns
    +0134     [hasEc,~]   = ismember(model.rxns,modRxns);
    +0135     hasEc       = find(hasEc & updateRxns);
    +0136     [~,rxnIdx]   = ismember(modRxns,model.rxns);
    +0137     for i = 1:numel(hasEc)
    +0138         % Get all isozymes per reaction
    +0139         ecIdx = find(rxnIdx == hasEc(i));
    +0140         % ecIdx = strcmp(model.rxns(hasEc(i)),modRxns);
    +0141         % Multiply enzymes with their MW (they are then automatically
    +0142         % summed per reaction), and divide by their kcat, to get a vector
    +0143         % of MW/kcat values.
    +0144         MWkcat = (model.ec.rxnEnzMat(ecIdx,:) * model.ec.mw) ./ model.ec.kcat(ecIdx);
    +0145         % If kcat was zero, MWkcat is Inf (or NaN without enzymes). An
    +0146         % isozyme row without any enzyme has MWkcat zero. Drop those
    +0147         % isozymes *before* selecting the cheapest one: including them in
    +0148         % the min() below would let an isozyme with no kcat or no enzyme
    +0149         % always win over a real kcat on another isozyme of the same reaction.
    +0150         % A row with a kcat that is not positive or an enzyme mass that is not
    +0151         % positive has no usable cost either.
    +0152         hasEnzyme = full(sum(model.ec.rxnEnzMat(ecIdx,:) ~= 0,2)) > 0;
    +0153         enzMass   = full(model.ec.rxnEnzMat(ecIdx,:) * model.ec.mw);
    +0154         validKcat = ~isinf(MWkcat) & ~isnan(MWkcat) & hasEnzyme & ...
    +0155             model.ec.kcat(ecIdx) > 0 & enzMass > 0;
    +0156         if any(validKcat)
    +0157             % Select the lowest MW/kcat (= most efficient), and convert to /hour
    +0158             model.S(prot_pool_idx, hasEc(i)) = -min(MWkcat(validKcat)/3600);
    +0159         else
    +0160             % No isozyme of this reaction has a usable kcat; leave it
    +0161             % unconstrained by enzyme usage.
    +0162             model.S(prot_pool_idx, hasEc(i)) = 0;
    +0163         end
    +0164     end
    +0165 end
    +0166 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/findMetSmiles.html b/doc/src/change_model/findMetSmiles.html new file mode 100644 index 00000000..0b5a10a0 --- /dev/null +++ b/doc/src/change_model/findMetSmiles.html @@ -0,0 +1,192 @@ + + + + Description of findMetSmiles + + + + + + + + + +
    Home > src > change_model > findMetSmiles.m
    + + + +

    findMetSmiles +

    + +

    PURPOSE ^

    +
    findMetSmiles Query PubChem by metabolite names to obtain SMILES.
    + +

    SYNOPSIS ^

    +
    function [model,noSMILES] = findMetSmiles(model, varargin)
    + +

    DESCRIPTION ^

    +
     findMetSmiles  Query PubChem by metabolite names to obtain SMILES.
    +
    + Matches are cached in tutorials/***/data/smilesDB.tsv, which is checked
    + first on subsequent runs so repeated queries are avoided. If the model
    + already has a metSmiles field, non-empty entries are left unchanged.
    +
    + Parameters
    + ----------
    + model : struct
    +     a model whose metNames field is used to find the relevant SMILES.
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + verbose : logical
    +     whether progress should be reported (default true).
    +
    + Returns
    + -------
    + model : struct
    +     model with model.metSmiles specified.
    + noSMILES : cell
    +     metabolite names for which no SMILES could be found.
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function [model,noSMILES] = findMetSmiles(model, varargin)
    +0002 % findMetSmiles  Query PubChem by metabolite names to obtain SMILES.
    +0003 %
    +0004 % Matches are cached in tutorials/***/data/smilesDB.tsv, which is checked
    +0005 % first on subsequent runs so repeated queries are avoided. If the model
    +0006 % already has a metSmiles field, non-empty entries are left unchanged.
    +0007 %
    +0008 % Parameters
    +0009 % ----------
    +0010 % model : struct
    +0011 %     a model whose metNames field is used to find the relevant SMILES.
    +0012 %
    +0013 % Name-Value Arguments
    +0014 % --------------------
    +0015 % modelAdapter : ModelAdapter
    +0016 %     a loaded model adapter (default: the current default model adapter).
    +0017 % verbose : logical
    +0018 %     whether progress should be reported (default true).
    +0019 %
    +0020 % Returns
    +0021 % -------
    +0022 % model : struct
    +0023 %     model with model.metSmiles specified.
    +0024 % noSMILES : cell
    +0025 %     metabolite names for which no SMILES could be found.
    +0026 %
    +0027 p = parseGECKOargs(varargin, { ...
    +0028     'modelAdapter', []; ...
    +0029     'verbose',      true});
    +0030 modelAdapter = p.modelAdapter;
    +0031 verbose      = p.verbose;
    +0032 if isempty(verbose); verbose = true; end
    +0033 
    +0034 if isempty(modelAdapter)
    +0035     modelAdapter = ModelAdapterManager.getDefault();
    +0036     if isempty(modelAdapter)
    +0037         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0038     end
    +0039 end
    +0040 params = modelAdapter.params;
    +0041 
    +0042 [uniqueNames, ~, uniqueIdx] = unique(regexprep(model.metNames,'^prot_.*',''));
    +0043 uniqueSmiles(1:numel(uniqueNames),1) = {''};
    +0044 metMatch = false(length(uniqueNames),1);
    +0045 metMatch(strcmp(uniqueNames,'')) = 1; % No need trying to match empty fields
    +0046 if verbose; fprintf('Check for local SMILES database... '); end
    +0047 smilesDBfile = (fullfile(params.path,'data','smilesDB.tsv'));
    +0048 if exist(smilesDBfile,'file')==2
    +0049     fID = fopen(smilesDBfile,'r');
    +0050     raw = textscan(fID,'%s %s','Delimiter','\t','HeaderLines',0);
    +0051     fclose(fID);
    +0052     smilesDB.names = raw{1};
    +0053     smilesDB.smile = raw{2};
    +0054     [metMatch, metIdx] = ismember(uniqueNames,smilesDB.names);
    +0055     uniqueSmiles(metMatch) = smilesDB.smile(metIdx(metMatch));
    +0056     if verbose; fprintf('done.\n'); end
    +0057 else
    +0058     if verbose; fprintf('not found.\n'); end
    +0059 end
    +0060 
    +0061 if any(~metMatch)
    +0062     PB = progressReport(numel(uniqueNames), 'Querying PubChem for SMILES by metabolite names');
    +0063     webOptions = weboptions('Timeout', 30);
    +0064     for i = 1:numel(uniqueNames)
    +0065         PB.count;
    +0066         if metMatch(i)
    +0067             continue;
    +0068         end
    +0069         retry = 0;
    +0070         while retry < 10
    +0071             try
    +0072                 smileResult       = webread(['https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/' uniqueNames{i} '/property/CanonicalSMILES/TXT'], webOptions);
    +0073                 %Sometimes multiple lines are given, with alternative SMILES. Only
    +0074                 %keep the first suggestion.
    +0075                 smileResult       = regexp(smileResult,'(^\S*)\n','once','tokens');
    +0076                 uniqueSmiles{i,1} = smileResult{1,1};
    +0077                 retry = 15; % success: no retry
    +0078             catch exception
    +0079                 %Sometimes the call fails, for example since the server is busy. In those cases
    +0080                 %we will try 10 times. Some errors however are because the metabolite
    +0081                 %name does no exist in the database (404) or some other error (the metabolite contains
    +0082                 %a slash or similar, 400 or 500). In those cases we can
    +0083                 %immediately give up.
    +0084                 if (strcmp(exception.identifier, 'MATLAB:webservices:HTTP404StatusCodeError') || ...
    +0085                         strcmp(exception.identifier, 'MATLAB:webservices:HTTP400StatusCodeError') || ...
    +0086                         strcmp(exception.identifier, 'MATLAB:webservices:HTTP500StatusCodeError'))
    +0087                     uniqueSmiles(i) = {''};
    +0088                     retry = 15;
    +0089                 else
    +0090                     retry = retry + 1;
    +0091                 end
    +0092             end
    +0093         if retry == 10
    +0094             error('Cannot reach PubChem. Check your internet connection and try again.')
    +0095         end
    +0096         end
    +0097         % Append one line each time, in case internet connection is lost
    +0098         % halfway. Open & close file each time to avoid leaving the file
    +0099         % open when breaking the function.
    +0100         out = [uniqueNames(i), uniqueSmiles(i)];
    +0101         fID = fopen(smilesDBfile,'a');
    +0102         fprintf(fID,'%s\t%s\n',out{:});
    +0103         fclose(fID);
    +0104     end
    +0105     PB.done;
    +0106     if verbose
    +0107         fprintf('Model-specific SMILES database stored at %s\n',smilesDBfile);
    +0108     end
    +0109 end
    +0110 newSmiles = uniqueSmiles(uniqueIdx);
    +0111 noSMILES = cellfun(@isempty,uniqueSmiles);
    +0112 successRatio = 1-(numel(find(noSMILES))/numel(uniqueSmiles));
    +0113 fprintf('SMILES could be found for %s%% of the unique metabolite names.\n',num2str(successRatio*100,'%.0f'))
    +0114 noSMILES = uniqueNames(noSMILES);
    +0115 
    +0116 if ~isfield(model,'metSmiles') || all(cellfun(@isempty,model.metSmiles))
    +0117     model.metSmiles = newSmiles;
    +0118 else
    +0119     emptySmiles = cellfun(@isempty,model.metSmiles);
    +0120     model.metSmiles(emptySmiles) = newSmiles(emptySmiles);
    +0121 end
    +0122 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/getComplexData.html b/doc/src/change_model/getComplexData.html new file mode 100644 index 00000000..6809fddc --- /dev/null +++ b/doc/src/change_model/getComplexData.html @@ -0,0 +1,273 @@ + + + + Description of getComplexData + + + + + + + + + +
    Home > src > change_model > getComplexData.m
    + + + +

    getComplexData +

    + +

    PURPOSE ^

    +
    getComplexData Download curated complex stochiometries from Complex Portal.
    + +

    SYNOPSIS ^

    +
    function complexInfo = getComplexData(varargin)
    + +

    DESCRIPTION ^

    +
     getComplexData  Download curated complex stochiometries from Complex Portal.
    +
    + Downloads curated complex stochiometries from the EMBL-EBI Complex Portal
    + database. Writes data/ComplexPortal.json in the obj.params.path specified
    + in the model adapter.
    +
    + Name-Value Arguments
    + --------------------
    + taxonomicID : double
    +     taxonomic identifier for which complex data should be downloaded. Only
    +     taxonomic identifiers allowed are those included on Complex Portal:
    +     https://www.ebi.ac.uk/complexportal/complex/organisms. If empty, no
    +     complex data is downloaded; if 0 (zero), complex data from all
    +     organisms in Complex Portal is downloaded.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + complexInfo : struct
    +     structure with data downloaded from Complex Portal (fields described
    +     under Notes).
    +
    + Notes
    + -----
    + The complexInfo structure has the following fields:
    +
    + - complexID : id of the complex on Complex Portal.
    + - name : name of the complex on Complex Portal.
    + - species : organism containing the complex.
    + - geneName : names of the genes in the complex.
    + - protID : Uniprot IDs of the proteins in the complex.
    + - stochiometry : the complex stochiometry given in the same order as the genes and proteins in geneName and protID.
    + - defined : 0 if Complex Portal has no defined stochiometry, 1 if defined subunit stochiometry is given, 2 if complex consists of sub-complexes, whose subunit stochiometries are given.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     complexInfo = getComplexData(organism, modelAdapter);
    +     complexInfo = getComplexData('taxonomicID', organism);
    +
    + See also
    + --------
    + applyComplexData, makeEcModel
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • applyComplexData applyComplexData Apply complex subunit stoichiometry to an ecModel.
    + + + + +

    SOURCE CODE ^

    +
    0001 function complexInfo = getComplexData(varargin)
    +0002 % getComplexData  Download curated complex stochiometries from Complex Portal.
    +0003 %
    +0004 % Downloads curated complex stochiometries from the EMBL-EBI Complex Portal
    +0005 % database. Writes data/ComplexPortal.json in the obj.params.path specified
    +0006 % in the model adapter.
    +0007 %
    +0008 % Name-Value Arguments
    +0009 % --------------------
    +0010 % taxonomicID : double
    +0011 %     taxonomic identifier for which complex data should be downloaded. Only
    +0012 %     taxonomic identifiers allowed are those included on Complex Portal:
    +0013 %     https://www.ebi.ac.uk/complexportal/complex/organisms. If empty, no
    +0014 %     complex data is downloaded; if 0 (zero), complex data from all
    +0015 %     organisms in Complex Portal is downloaded.
    +0016 % modelAdapter : ModelAdapter
    +0017 %     a loaded model adapter (default: the current default model adapter).
    +0018 %
    +0019 % Returns
    +0020 % -------
    +0021 % complexInfo : struct
    +0022 %     structure with data downloaded from Complex Portal (fields described
    +0023 %     under Notes).
    +0024 %
    +0025 % Notes
    +0026 % -----
    +0027 % The complexInfo structure has the following fields:
    +0028 %
    +0029 % - complexID : id of the complex on Complex Portal.
    +0030 % - name : name of the complex on Complex Portal.
    +0031 % - species : organism containing the complex.
    +0032 % - geneName : names of the genes in the complex.
    +0033 % - protID : Uniprot IDs of the proteins in the complex.
    +0034 % - stochiometry : the complex stochiometry given in the same order as the genes and proteins in geneName and protID.
    +0035 % - defined : 0 if Complex Portal has no defined stochiometry, 1 if defined subunit stochiometry is given, 2 if complex consists of sub-complexes, whose subunit stochiometries are given.
    +0036 %
    +0037 % Examples
    +0038 % --------
    +0039 %     % optional arguments may be given positionally or as name-value pairs:
    +0040 %     complexInfo = getComplexData(organism, modelAdapter);
    +0041 %     complexInfo = getComplexData('taxonomicID', organism);
    +0042 %
    +0043 % See also
    +0044 % --------
    +0045 % applyComplexData, makeEcModel
    +0046 
    +0047 p = parseGECKOargs(varargin, { ...
    +0048     'taxonomicID',  []; ...
    +0049     'modelAdapter', []});
    +0050 taxonomicID  = p.taxonomicID;
    +0051 modelAdapter = p.modelAdapter;
    +0052 
    +0053 if isempty(modelAdapter)
    +0054     modelAdapter = ModelAdapterManager.getDefault();
    +0055     if isempty(modelAdapter)
    +0056         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0057     end
    +0058 end
    +0059 
    +0060 if isempty(taxonomicID)
    +0061     taxonomicID = modelAdapter.getParameters().complex.taxonomicID;
    +0062 end
    +0063 
    +0064 params = modelAdapter.params;
    +0065 if isempty(taxonomicID) % Can be empty when gathered from model adapter
    +0066     printOrange('WARNING: No taxonomicID specified.');
    +0067     return
    +0068 elseif taxonomicID == 0
    +0069     taxonomicID = [];
    +0070 end
    +0071 
    +0072 webOptions = weboptions('Timeout', 30);
    +0073 try
    +0074     url1 = 'https://www.ebi.ac.uk/intact/complex-ws/search/*';
    +0075     if ~isempty(taxonomicID)
    +0076         url1 = [url1 '?facets=species&filters=species:("' num2str(taxonomicID) '")'];
    +0077     end
    +0078     data = webread(url1,webOptions);
    +0079 catch ME
    +0080     if (strcmp(ME.identifier,'MATLAB:webservices:HTTP404StatusCodeError'))
    +0081         error('Cannot connect to the Complex Portal, perhaps the server is not responding');
    +0082     end
    +0083 end
    +0084 if data.size == 0
    +0085     error('No data could be gathered from Complex Portal for the specified taxonomicID.')
    +0086 end
    +0087 complexData = cell(data.size,7);
    +0088 
    +0089 PB = progressReport(data.size, 'Retrieving information for complexes');
    +0090 for i = 1:data.size
    +0091     PB.count;
    +0092     url2 = 'https://www.ebi.ac.uk/intact/complex-ws/complex/';
    +0093     complexID = data.elements(i,1).complexAC;
    +0094     try
    +0095         temp = webread([url2 complexID],webOptions);
    +0096     catch ME
    +0097         if (strcmp(ME.identifier,'MATLAB:webservices:HTTP404StatusCodeError'))
    +0098             printOrange(['WARNING: Cannot retrieve the information for ' complexID '.\n']);
    +0099         end
    +0100         temp = [];
    +0101     end
    +0102 
    +0103     if ~isempty(temp)
    +0104         complexData(i,1) = {temp.complexAc};
    +0105         complexData(i,2) = {temp.name};
    +0106         complexData(i,3) = {temp.species};
    +0107 
    +0108         idxIntType = find(strcmpi({temp.participants.interactorType}, 'protein'));
    +0109 
    +0110         % Some complex reported are 'stable complex', then, save the id
    +0111         % complex and but set the genes and protein to a empty string.
    +0112         if numel(idxIntType) > 0
    +0113             complexData(i,4) = {{temp.participants(idxIntType).name}};
    +0114             complexData(i,5) = {{temp.participants(idxIntType).identifier}};
    +0115         else
    +0116             complexData(i,4) = {{temp.participants.name}};
    +0117             complexData(i,5) = {{temp.participants.identifier}};
    +0118         end
    +0119 
    +0120         % Portal complex has two stochiometry values, a minimum and
    +0121         % maximum value. Only minimum will be store. In some cases,
    +0122         % some complex does not have stochiometry coefficient, then, it
    +0123         % will be fill with zeros
    +0124         if ~cellfun('isempty',{temp.participants.stochiometry})
    +0125             % For some reason, if there is only one protein in the complex
    +0126             % split function does nor return a cell nx2, instead is 2x1,
    +0127             % then assign an incorrect stochiometry
    +0128             switch numel(idxIntType)
    +0129                 case 0 % Contains complexes
    +0130                     stochiometry = split({temp.participants.stochiometry}.', ',');
    +0131                     complexData(i,7) = {2};
    +0132                 case 1 % Contains one protein
    +0133                     stochiometry = split({temp.participants(idxIntType).stochiometry}.', ',').';
    +0134                     complexData(i,7) = {1};
    +0135                 otherwise
    +0136                     stochiometry = split({temp.participants(idxIntType).stochiometry}.', ',');
    +0137                     complexData(i,7) = {1};
    +0138             end
    +0139             values = str2double(erase(stochiometry(:,1),"minValue: ")).';
    +0140             complexData(i,6) = {values};
    +0141         else
    +0142             complexData(i,6) = {repelem(0,numel(complexData{i,4}))};
    +0143             complexData(i,7) = {0};
    +0144         end
    +0145     end
    +0146 end
    +0147 fprintf('\n');
    +0148 
    +0149 % Expand complexes of complexes
    +0150 complexComplex = find([complexData{:,7}]==2);
    +0151 if ~isempty(complexComplex)
    +0152     for i=1:numel(complexComplex)
    +0153         subComplex    = complexData{complexComplex(i),5};
    +0154         subComplexS   = complexData{complexComplex(i),6};
    +0155         subComplexIdx = find(ismember(complexData(:,1),subComplex));
    +0156         allGenes = horzcat(complexData{subComplexIdx,4});
    +0157         allProts = horzcat(complexData{subComplexIdx,5});
    +0158         allStoch = {complexData{subComplexIdx,6}};
    +0159         for j=1:numel(subComplex)
    +0160             allStoch{j}=allStoch{j}*subComplexS(j);
    +0161         end
    +0162         allStoch = horzcat(allStoch{:});
    +0163         [allGenes,ia,ic] = unique(allGenes,'stable');
    +0164         allProts = allProts(ia);
    +0165         allStoch = splitapply(@sum, allStoch', ic);
    +0166         complexData{complexComplex(i),4} = allGenes;
    +0167         complexData{complexComplex(i),5} = allProts;
    +0168         complexData{complexComplex(i),6} = allStoch;
    +0169     end
    +0170 end
    +0171 
    +0172 rowHeadings = {'complexID','name','species','geneName','protID','stochiometry','defined'};
    +0173 
    +0174 complexInfo = cell2struct(complexData, rowHeadings, 2);
    +0175 
    +0176 % Convert to a JSON file
    +0177 jsontxt = jsonencode(cell2table(complexData, 'VariableNames', rowHeadings));
    +0178 % Write to a JSON file
    +0179 fid = fopen(fullfile(params.path,'data','ComplexPortal.json'), 'w');
    +0180 fprintf(fid, '%s', jsontxt);
    +0181 fclose(fid);
    +0182 fprintf('Model-specific ComplexPortal database stored at %s\n',fullfile(params.path,'data','ComplexPortal.json'));
    +0183 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/getKcatAcrossIsozymes.html b/doc/src/change_model/getKcatAcrossIsozymes.html new file mode 100644 index 00000000..afc79e45 --- /dev/null +++ b/doc/src/change_model/getKcatAcrossIsozymes.html @@ -0,0 +1,129 @@ + + + + Description of getKcatAcrossIsozymes + + + + + + + + + +
    Home > src > change_model > getKcatAcrossIsozymes.m
    + + + +

    getKcatAcrossIsozymes +

    + +

    PURPOSE ^

    +
    getKcatAcrossIsozymes Fill missing kcats from isozymes of the same reaction.
    + +

    SYNOPSIS ^

    +
    function model = getKcatAcrossIsozymes(model)
    + +

    DESCRIPTION ^

    +
     getKcatAcrossIsozymes  Fill missing kcats from isozymes of the same reaction.
    +
    + For reactions without kcat value (0 in model.ec.kcat), isozymes are found
    + (being based on the same reaction in the conventional GEM), that do have a
    + kcat value assigned. The mean kcat value of these isozymes is then used to
    + fill in model.ec.kcat. Only isozymes with a kcat above 0 enter the mean: a
    + NaN or negative kcat of an isozyme is left out, and an entry whose kcat is
    + NaN is not filled.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in full GECKO 3 format (with ecModel.ec structure), not
    +     GECKO light.
    +
    + Returns
    + -------
    + model : struct
    +     an ecModel with kcat values assigned to isozymes in model.ec.kcat.
    +
    + Examples
    + --------
    +     model = getKcatAcrossIsozymes(model);
    +
    + See also
    + --------
    + applyKcatConstraints, setKcatForReactions
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function model = getKcatAcrossIsozymes(model)
    +0002 % getKcatAcrossIsozymes  Fill missing kcats from isozymes of the same reaction.
    +0003 %
    +0004 % For reactions without kcat value (0 in model.ec.kcat), isozymes are found
    +0005 % (being based on the same reaction in the conventional GEM), that do have a
    +0006 % kcat value assigned. The mean kcat value of these isozymes is then used to
    +0007 % fill in model.ec.kcat. Only isozymes with a kcat above 0 enter the mean: a
    +0008 % NaN or negative kcat of an isozyme is left out, and an entry whose kcat is
    +0009 % NaN is not filled.
    +0010 %
    +0011 % Parameters
    +0012 % ----------
    +0013 % model : struct
    +0014 %     an ecModel in full GECKO 3 format (with ecModel.ec structure), not
    +0015 %     GECKO light.
    +0016 %
    +0017 % Returns
    +0018 % -------
    +0019 % model : struct
    +0020 %     an ecModel with kcat values assigned to isozymes in model.ec.kcat.
    +0021 %
    +0022 % Examples
    +0023 % --------
    +0024 %     model = getKcatAcrossIsozymes(model);
    +0025 %
    +0026 % See also
    +0027 % --------
    +0028 % applyKcatConstraints, setKcatForReactions
    +0029 
    +0030 if model.ec.geckoLight
    +0031     error('Provided model is a GECKO light version, this function is not relevant for such models')
    +0032 end
    +0033 if all(model.ec.kcat==0)
    +0034     printOrange('WARNING: No kcat values are provided in model.ec.kcat, model remains unchanged.\n');
    +0035     return
    +0036 end
    +0037 
    +0038 noKcats     = model.ec.kcat==0;
    +0039 hasKcat     = model.ec.kcat>0; % NaN and negative kcats are not isozyme values
    +0040 rxnIDs      = regexprep(model.ec.rxns,'_EXP_\d+','');
    +0041 noKcatID    = rxnIDs(noKcats);
    +0042 yesKcatID   = rxnIDs(hasKcat);
    +0043 yesKcatVal  = model.ec.kcat(hasKcat);
    +0044 
    +0045 noKcatVal   = cellfun(@(x) strcmp(x, yesKcatID), noKcatID, 'UniformOutput', false);
    +0046 noKcatVal   = cell2mat(cellfun(@(x) mean(yesKcatVal(x)), noKcatVal, 'UniformOutput', false));
    +0047 
    +0048 newKcat     = find(~isnan(noKcatVal));
    +0049 newKcatIdx  = find(noKcats);
    +0050 newKcatIdx  = newKcatIdx(newKcat);
    +0051 newKcat     = noKcatVal(newKcat);
    +0052 
    +0053 model.ec.kcat(newKcatIdx) = newKcat;
    +0054 model.ec.source(newKcatIdx) = {'isozymes'};
    +0055 end
    +0056
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/getReactionsFromEnzyme.html b/doc/src/change_model/getReactionsFromEnzyme.html new file mode 100644 index 00000000..4153a532 --- /dev/null +++ b/doc/src/change_model/getReactionsFromEnzyme.html @@ -0,0 +1,121 @@ + + + + Description of getReactionsFromEnzyme + + + + + + + + + +
    Home > src > change_model > getReactionsFromEnzyme.m
    + + + +

    getReactionsFromEnzyme +

    + +

    PURPOSE ^

    +
    getReactionsFromEnzyme Get all reactions annotated to a particular enzyme.
    + +

    SYNOPSIS ^

    +
    function [rxns, kcat, idx, rxnNames, grRules] = getReactionsFromEnzyme(ecModel,proteinId)
    + +

    DESCRIPTION ^

    +
     getReactionsFromEnzyme  Get all reactions annotated to a particular enzyme.
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    + proteinId : char
    +     protein identifier, matching ecModel.ec.enzymes case-insensitively.
    +
    + Returns
    + -------
    + rxns : cell
    +     reactions that are associated with this enzyme.
    + kcat : double
    +     kcat values of the corresponding reactions.
    + idx : double
    +     index of the reactions in ecModel.ec.rxns.
    + rxnNames : cell
    +     names of the reactions.
    + grRules : cell
    +     grRules of the reactions.
    +
    + Notes
    + -----
    + An unmatched proteinId is not an error: all five outputs are returned
    + empty, with no warning. Matching against ecModel.ec.enzymes is
    + case-insensitive.
    +
    + Examples
    + --------
    +     [rxns, kcat, idx, rxnNames, grRules] = getReactionsFromEnzyme(ecModel, proteinId);
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function [rxns, kcat, idx, rxnNames, grRules] = getReactionsFromEnzyme(ecModel,proteinId)
    +0002 % getReactionsFromEnzyme  Get all reactions annotated to a particular enzyme.
    +0003 %
    +0004 % Parameters
    +0005 % ----------
    +0006 % ecModel : struct
    +0007 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0008 % proteinId : char
    +0009 %     protein identifier, matching ecModel.ec.enzymes case-insensitively.
    +0010 %
    +0011 % Returns
    +0012 % -------
    +0013 % rxns : cell
    +0014 %     reactions that are associated with this enzyme.
    +0015 % kcat : double
    +0016 %     kcat values of the corresponding reactions.
    +0017 % idx : double
    +0018 %     index of the reactions in ecModel.ec.rxns.
    +0019 % rxnNames : cell
    +0020 %     names of the reactions.
    +0021 % grRules : cell
    +0022 %     grRules of the reactions.
    +0023 %
    +0024 % Notes
    +0025 % -----
    +0026 % An unmatched proteinId is not an error: all five outputs are returned
    +0027 % empty, with no warning. Matching against ecModel.ec.enzymes is
    +0028 % case-insensitive.
    +0029 %
    +0030 % Examples
    +0031 % --------
    +0032 %     [rxns, kcat, idx, rxnNames, grRules] = getReactionsFromEnzyme(ecModel, proteinId);
    +0033 
    +0034 protIdx     = find(strcmpi(ecModel.ec.enzymes,proteinId));
    +0035 ecRxnIdx    = find(ecModel.ec.rxnEnzMat(:,protIdx));
    +0036 rxns        = ecModel.ec.rxns(ecRxnIdx);
    +0037 kcat        = ecModel.ec.kcat(ecRxnIdx);
    +0038 
    +0039 idx         = ecRxnIdx;
    +0040 
    +0041 [~,rxnIdx]  = ismember(rxns,ecModel.rxns);
    +0042 rxnNames    = ecModel.rxnNames(rxnIdx);
    +0043 grRules     =  ecModel.grRules(rxnIdx);
    +0044 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/getSubsetEcModel.html b/doc/src/change_model/getSubsetEcModel.html new file mode 100644 index 00000000..e306ad73 --- /dev/null +++ b/doc/src/change_model/getSubsetEcModel.html @@ -0,0 +1,155 @@ + + + + Description of getSubsetEcModel + + + + + + + + + +
    Home > src > change_model > getSubsetEcModel.m
    + + + +

    getSubsetEcModel +

    + +

    PURPOSE ^

    +
    getSubsetEcModel Generate a context-specific ecModel from a general one.
    + +

    SYNOPSIS ^

    +
    function smallEcModel = getSubsetEcModel(bigEcModel,smallGEM)
    + +

    DESCRIPTION ^

    +
     getSubsetEcModel  Generate a context-specific ecModel from a general one.
    +
    + Generate a context-specific ecModel (strain/cell-line/tissue) by mapping
    + reactions and genes from a conventional context-specific GEM to a general
    + ecModel (bigEcModel), to yield a context-specific ecModel.
    +
    + Both models (bigEcModel and the smallGEM) should have derived from the
    + same starting model. If an ecModel with human-GEM 1.15.0 is made
    + (yielding the bigEcModel), then human-GEM 1.15.0 should also be the basis
    + from which the context-specific GEM (smallGEM) was generated by for
    + instance tINIT.
    +
    + Parameters
    + ----------
    + bigEcModel : struct
    +     enzyme-constrained version of conventional model of metabolism for a
    +     given species.
    + smallGEM : struct
    +     reduced model (subset of the general model) for a specific strain
    +     (microbes) or cell-line/tissues (mammals).
    +
    + Returns
    + -------
    + smallEcModel : struct
    +     enzyme-constrained version of the context-specific model.
    +
    + Examples
    + --------
    +     smallEcModel = getSubsetEcModel(bigEcModel,smallGEM);
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function smallEcModel = getSubsetEcModel(bigEcModel,smallGEM)
    +0002 % getSubsetEcModel  Generate a context-specific ecModel from a general one.
    +0003 %
    +0004 % Generate a context-specific ecModel (strain/cell-line/tissue) by mapping
    +0005 % reactions and genes from a conventional context-specific GEM to a general
    +0006 % ecModel (bigEcModel), to yield a context-specific ecModel.
    +0007 %
    +0008 % Both models (bigEcModel and the smallGEM) should have derived from the
    +0009 % same starting model. If an ecModel with human-GEM 1.15.0 is made
    +0010 % (yielding the bigEcModel), then human-GEM 1.15.0 should also be the basis
    +0011 % from which the context-specific GEM (smallGEM) was generated by for
    +0012 % instance tINIT.
    +0013 %
    +0014 % Parameters
    +0015 % ----------
    +0016 % bigEcModel : struct
    +0017 %     enzyme-constrained version of conventional model of metabolism for a
    +0018 %     given species.
    +0019 % smallGEM : struct
    +0020 %     reduced model (subset of the general model) for a specific strain
    +0021 %     (microbes) or cell-line/tissues (mammals).
    +0022 %
    +0023 % Returns
    +0024 % -------
    +0025 % smallEcModel : struct
    +0026 %     enzyme-constrained version of the context-specific model.
    +0027 %
    +0028 % Examples
    +0029 % --------
    +0030 %     smallEcModel = getSubsetEcModel(bigEcModel,smallGEM);
    +0031 
    +0032 % Check if models were derived from the same starting GEM
    +0033 Rxn_format = regexprep(bigEcModel.rxns,'_REV|_EXP_\d+','');
    +0034 rxnsDiff = find(~ismember(smallGEM.rxns,Rxn_format));
    +0035 if numel(rxnsDiff) > 0
    +0036     error('%s', ravenList(['While both models should have derived from the same starting ',...
    +0037             'GEM, the following reactions from smallGEM could not be found ',...
    +0038             'in bigEcModel:'],smallGEM.rxns(rxnsDiff),false));
    +0039 end
    +0040 
    +0041 % Check if original bigEcModel contains context-dependent protein constraints
    +0042 if any(bigEcModel.ub(startsWith(bigEcModel.rxns,'usage_prot_')) ~= 1000)
    +0043     printOrange(['WARNING: The bigEcModel is constraint by protein concentrations that are\n' ...
    +0044                  'likely not relevant in the constructed smallEcModel.\n']);
    +0045 end
    +0046 
    +0047 % Remove genes (and associated reactions) that are absent in smallGEM
    +0048 genesToRemove  = setdiff(bigEcModel.genes,smallGEM.genes);
    +0049 % If genesToRemove contains "standard", then remove this entry
    +0050 if ismember('standard', genesToRemove)
    +0051     genesToRemove(strcmp(genesToRemove, 'standard')) = [];
    +0052 end
    +0053 smallEcModel = removeGenes(bigEcModel,genesToRemove,true,true,false);
    +0054 
    +0055 % Remove genes from ec-structure
    +0056 enzToRemove = ismember(smallEcModel.ec.genes,genesToRemove);
    +0057 smallEcModel.ec.genes(enzToRemove)       = [];
    +0058 smallEcModel.ec.enzymes(enzToRemove)     = [];
    +0059 smallEcModel.ec.concs(enzToRemove)       = [];
    +0060 smallEcModel.ec.mw(enzToRemove)          = [];
    +0061 smallEcModel.ec.sequence(enzToRemove)    = [];
    +0062 smallEcModel.ec.rxnEnzMat(:,enzToRemove) = [];
    +0063 
    +0064 % Remove any reaction (except prot_ associated) that is absent from smallGEM
    +0065 trimRxns = regexprep(smallEcModel.rxns,'_REV|_EXP_\d+','');
    +0066 protRxns = startsWith(smallEcModel.rxns,{'usage_prot_','prot_pool_exchange'});
    +0067 keepRxns = ismember(trimRxns,smallGEM.rxns) | protRxns;
    +0068 smallEcModel = removeReactions(smallEcModel,~keepRxns, true, true, true);
    +0069 
    +0070 % Remove reactions from ec-structure
    +0071 ecRxnsToRemove = ~ismember(smallEcModel.ec.rxns,smallEcModel.rxns);
    +0072 
    +0073 smallEcModel.ec.rxns(ecRxnsToRemove)        = [];
    +0074 smallEcModel.ec.kcat(ecRxnsToRemove)        = [];
    +0075 smallEcModel.ec.source(ecRxnsToRemove)      = [];
    +0076 smallEcModel.ec.notes(ecRxnsToRemove)       = [];
    +0077 smallEcModel.ec.eccodes(ecRxnsToRemove)     = [];
    +0078 smallEcModel.ec.rxnEnzMat(ecRxnsToRemove,:) = [];
    +0079 end
    +0080
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/index.html b/doc/src/change_model/index.html new file mode 100644 index 00000000..66f0ed8f --- /dev/null +++ b/doc/src/change_model/index.html @@ -0,0 +1,29 @@ + + + + Index for Directory src/change_model + + + + + + + + + + +
    < Master indexIndex for src/change_model >
    + +

    Index for src/change_model

    + +

    Matlab files in this directory:

    + +
     addNewRxnsToECaddNewRxnsToEC Add new reactions to an enzyme-constrained model.
     applyComplexDataapplyComplexData Apply complex subunit stoichiometry to an ecModel.
     applyCustomKcatsapplyCustomKcats Apply user-defined kcats to an ecModel.
     applyKcatConstraintsapplyKcatConstraints Apply kcat-derived enzyme constraints to an ecModel.
     findMetSmilesfindMetSmiles Query PubChem by metabolite names to obtain SMILES.
     getComplexDatagetComplexData Download curated complex stochiometries from Complex Portal.
     getKcatAcrossIsozymesgetKcatAcrossIsozymes Fill missing kcats from isozymes of the same reaction.
     getReactionsFromEnzymegetReactionsFromEnzyme Get all reactions annotated to a particular enzyme.
     getSubsetEcModelgetSubsetEcModel Generate a context-specific ecModel from a general one.
     makeEcModelmakeEcModel Expand a conventional GEM into a basic ecModel.
     mapRxnsToConvmapRxnsToConv Map ecModel fluxes back to the conventional starting model.
     setKcatForReactionssetKcatForReactions Change the kcat value for selected reactions.
     setProtPoolSizesetProtPoolSize Set the limit of the total protein usage in the model.
     upgradeEcModelupgradeEcModel Bring an ecModel made with GECKO 3 to the GECKO 4 format.
    + + + + +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/makeEcModel.html b/doc/src/change_model/makeEcModel.html new file mode 100644 index 00000000..f0870aea --- /dev/null +++ b/doc/src/change_model/makeEcModel.html @@ -0,0 +1,669 @@ + + + + Description of makeEcModel + + + + + + + + + +
    Home > src > change_model > makeEcModel.m
    + + + +

    makeEcModel +

    + +

    PURPOSE ^

    +
    makeEcModel Expand a conventional GEM into a basic ecModel.
    + +

    SYNOPSIS ^

    +
    function [model, noUniprot] = makeEcModel(model, varargin)
    + +

    DESCRIPTION ^

    +
     makeEcModel  Expand a conventional GEM into a basic ecModel.
    +
    + Expands a conventional genome-scale model (in RAVEN format) with enzyme
    + information and prepares the reactions for integration of enzyme usage
    + coefficients. This function contains all the steps that need to be done to
    + get a basic ecModel, without incorporating any kcat values or constraints
    + yet. This function should only have to be run once for a model.
    +
    + Parameters
    + ----------
    + model : struct
    +     a model in RAVEN format.
    +
    + Name-Value Arguments
    + --------------------
    + geckoLight : logical
    +     true if a simplified GECKO light model should be generated (default
    +     false).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + model : struct
    +     an ecModel in GECKO 3 format, with a model.ec structure where enzyme
    +     and kcat information are stored. Protein pseudometabolites and their
    +     draw reactions are added to the model, but their usage is not yet
    +     implemented (due to absent kcat values at this stage).
    + noUniprot : cell
    +     genes for which no information could be found in either the Uniprot
    +     or, as fallback, the KEGG database.
    +
    + Notes
    + -----
    + The function goes through the following steps:
    +
    + 1.  Remove gene associations from pseudoreactions.
    + 2.  Invert irreversible backwards reactions.
    + 3.  Correct 'rev' vector to match lb and ub vectors.
    + 4.  Convert to irreversible model (splits reversible reactions).
    + 5.  [Skipped with geckoLight:] Expand model to split reactions with 'OR'
    +     in grRules (each reaction is then catalyzed by one enzyme (complex)).
    + 6.  Make empty model.ec structure, that will contain enzyme and kcat
    +     information. One entry per reaction, where isozymes have multiple
    +     entries. This model.ec structure will later be populated with kcat
    +     values. For geckoLight the structure is different, where each reaction
    +     can have multiple isozymes.
    + 7.  Add enzyme information fields to model.ec structure: MW, sequence.
    +     Data is gathered from UniProt, with KEGG used as a fallback for genes
    +     that UniProt does not match.
    + 8.  Populate model.ec structure with information from each reaction.
    + 9.  [Skipped with geckoLight:] Add proteins as pseudometabolites.
    + 10. Add prot_pool pseudometabolite.
    + 11. [Skipped with geckoLight:] Add usage reactions for the protein
    +     pseudometabolites, replenishing from the protein pool (default, can be
    +     changed to consider proteomics data at later stage).
    + 12. Add protein pool reaction, without upper bound.
    +
    + Note that while protein pseudometabolites, draw & pool reactions might be
    + added to the model, the enzyme usage is not yet incorporated in each
    + metabolic reaction, so enzymes will not be used. applyKcatConstraints
    + incorporates protein pseudometabolites in reactions as enzyme usages by
    + applying the specified kcats as constraints.
    +
    + The model.ec structure has the following fields:
    +
    + - geckoLight : 0 if full model, 1 if light.
    + - rxns : reaction identifiers that correspond to model.rxns.
    + - kcat : kcat values - not set here.
    + - source : specifies where the kcats come from - not set here.
    + - notes : notes that can be set by downstream functions - not set here.
    + - eccodes : enzyme codes for each enzyme - not set here.
    + - genes : the genes involved in the kcats - not necessarily the same as model.genes, since some genes may not be found in databases etc.
    + - enzymes : Uniprot protein identifiers for the genes; for a gene that
    +   was only matched via the KEGG fallback and has no UniProt accession on
    +   its KEGG entry, the bare KEGG gene identifier is used instead.
    + - mw : molecular weights of the enzymes.
    + - sequence : sequence of the genes/enzymes.
    + - concs : concentrations of the enzymes - not set here.
    + - rxnEnzMat : matrix of enzymes and rxns.
    +
    + The full model is split on all ORs in the GPRs, meaning that the reactions
    + will be duplicated for each isozyme. Only the rxns with genes are added.
    + The fields rxns, eccodes, kcat, source and notes will therefore have one
    + entry per reaction. The fields genes, enzymes, mw, sequence and concs will
    + have one entry per gene. The rxnEnzMat is a matrix with reactions and
    + genes, mapping which genes are connected to which reaction (where isozymes
    + have different reactions).
    +
    + The light model works a bit differently. The model has the same number of
    + rxns as the original model, but expanded since it is reversible + one the
    + extra prot maintenance rxn and one extra prot_pool rxn. However, the ec
    + fields rxns, eccodes, kcat, source and notes are duplicated for each
    + isozyme, sorted the same way as model.rxns. So, in model.ec.rxns, the same
    + reaction will appear several times after one another, one entry per
    + izozyme, with corresponding values for that isozyme. These fields
    + therefore have the same length as for the full model. The fields genes,
    + enzymes, mw, sequence and concs are the same here as in the full model.
    + The rxnEnzMat maps the model.ec.rxns entries to genes and is therefore of
    + the same size as for the full model.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     [model, noUniprot] = makeEcModel(model);
    +     [model, noUniprot] = makeEcModel(model, 'geckoLight', true);
    +
    + See also
    + --------
    + applyKcatConstraints, applyComplexData
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [model, noUniprot] = makeEcModel(model, varargin)
    +0002 % makeEcModel  Expand a conventional GEM into a basic ecModel.
    +0003 %
    +0004 % Expands a conventional genome-scale model (in RAVEN format) with enzyme
    +0005 % information and prepares the reactions for integration of enzyme usage
    +0006 % coefficients. This function contains all the steps that need to be done to
    +0007 % get a basic ecModel, without incorporating any kcat values or constraints
    +0008 % yet. This function should only have to be run once for a model.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % model : struct
    +0013 %     a model in RAVEN format.
    +0014 %
    +0015 % Name-Value Arguments
    +0016 % --------------------
    +0017 % geckoLight : logical
    +0018 %     true if a simplified GECKO light model should be generated (default
    +0019 %     false).
    +0020 % modelAdapter : ModelAdapter
    +0021 %     a loaded model adapter (default: the current default model adapter).
    +0022 %
    +0023 % Returns
    +0024 % -------
    +0025 % model : struct
    +0026 %     an ecModel in GECKO 3 format, with a model.ec structure where enzyme
    +0027 %     and kcat information are stored. Protein pseudometabolites and their
    +0028 %     draw reactions are added to the model, but their usage is not yet
    +0029 %     implemented (due to absent kcat values at this stage).
    +0030 % noUniprot : cell
    +0031 %     genes for which no information could be found in either the Uniprot
    +0032 %     or, as fallback, the KEGG database.
    +0033 %
    +0034 % Notes
    +0035 % -----
    +0036 % The function goes through the following steps:
    +0037 %
    +0038 % 1.  Remove gene associations from pseudoreactions.
    +0039 % 2.  Invert irreversible backwards reactions.
    +0040 % 3.  Correct 'rev' vector to match lb and ub vectors.
    +0041 % 4.  Convert to irreversible model (splits reversible reactions).
    +0042 % 5.  [Skipped with geckoLight:] Expand model to split reactions with 'OR'
    +0043 %     in grRules (each reaction is then catalyzed by one enzyme (complex)).
    +0044 % 6.  Make empty model.ec structure, that will contain enzyme and kcat
    +0045 %     information. One entry per reaction, where isozymes have multiple
    +0046 %     entries. This model.ec structure will later be populated with kcat
    +0047 %     values. For geckoLight the structure is different, where each reaction
    +0048 %     can have multiple isozymes.
    +0049 % 7.  Add enzyme information fields to model.ec structure: MW, sequence.
    +0050 %     Data is gathered from UniProt, with KEGG used as a fallback for genes
    +0051 %     that UniProt does not match.
    +0052 % 8.  Populate model.ec structure with information from each reaction.
    +0053 % 9.  [Skipped with geckoLight:] Add proteins as pseudometabolites.
    +0054 % 10. Add prot_pool pseudometabolite.
    +0055 % 11. [Skipped with geckoLight:] Add usage reactions for the protein
    +0056 %     pseudometabolites, replenishing from the protein pool (default, can be
    +0057 %     changed to consider proteomics data at later stage).
    +0058 % 12. Add protein pool reaction, without upper bound.
    +0059 %
    +0060 % Note that while protein pseudometabolites, draw & pool reactions might be
    +0061 % added to the model, the enzyme usage is not yet incorporated in each
    +0062 % metabolic reaction, so enzymes will not be used. applyKcatConstraints
    +0063 % incorporates protein pseudometabolites in reactions as enzyme usages by
    +0064 % applying the specified kcats as constraints.
    +0065 %
    +0066 % The model.ec structure has the following fields:
    +0067 %
    +0068 % - geckoLight : 0 if full model, 1 if light.
    +0069 % - rxns : reaction identifiers that correspond to model.rxns.
    +0070 % - kcat : kcat values - not set here.
    +0071 % - source : specifies where the kcats come from - not set here.
    +0072 % - notes : notes that can be set by downstream functions - not set here.
    +0073 % - eccodes : enzyme codes for each enzyme - not set here.
    +0074 % - genes : the genes involved in the kcats - not necessarily the same as model.genes, since some genes may not be found in databases etc.
    +0075 % - enzymes : Uniprot protein identifiers for the genes; for a gene that
    +0076 %   was only matched via the KEGG fallback and has no UniProt accession on
    +0077 %   its KEGG entry, the bare KEGG gene identifier is used instead.
    +0078 % - mw : molecular weights of the enzymes.
    +0079 % - sequence : sequence of the genes/enzymes.
    +0080 % - concs : concentrations of the enzymes - not set here.
    +0081 % - rxnEnzMat : matrix of enzymes and rxns.
    +0082 %
    +0083 % The full model is split on all ORs in the GPRs, meaning that the reactions
    +0084 % will be duplicated for each isozyme. Only the rxns with genes are added.
    +0085 % The fields rxns, eccodes, kcat, source and notes will therefore have one
    +0086 % entry per reaction. The fields genes, enzymes, mw, sequence and concs will
    +0087 % have one entry per gene. The rxnEnzMat is a matrix with reactions and
    +0088 % genes, mapping which genes are connected to which reaction (where isozymes
    +0089 % have different reactions).
    +0090 %
    +0091 % The light model works a bit differently. The model has the same number of
    +0092 % rxns as the original model, but expanded since it is reversible + one the
    +0093 % extra prot maintenance rxn and one extra prot_pool rxn. However, the ec
    +0094 % fields rxns, eccodes, kcat, source and notes are duplicated for each
    +0095 % isozyme, sorted the same way as model.rxns. So, in model.ec.rxns, the same
    +0096 % reaction will appear several times after one another, one entry per
    +0097 % izozyme, with corresponding values for that isozyme. These fields
    +0098 % therefore have the same length as for the full model. The fields genes,
    +0099 % enzymes, mw, sequence and concs are the same here as in the full model.
    +0100 % The rxnEnzMat maps the model.ec.rxns entries to genes and is therefore of
    +0101 % the same size as for the full model.
    +0102 %
    +0103 % Examples
    +0104 % --------
    +0105 %     % optional arguments may be given positionally or as name-value pairs:
    +0106 %     [model, noUniprot] = makeEcModel(model);
    +0107 %     [model, noUniprot] = makeEcModel(model, 'geckoLight', true);
    +0108 %
    +0109 % See also
    +0110 % --------
    +0111 % applyKcatConstraints, applyComplexData
    +0112 
    +0113 p = parseGECKOargs(varargin, { ...
    +0114     'geckoLight',   false; ...
    +0115     'modelAdapter', []});
    +0116 geckoLight   = p.geckoLight;
    +0117 modelAdapter = p.modelAdapter;
    +0118 
    +0119 if ~islogical(geckoLight) && ~(geckoLight == 0) && ~(geckoLight == 1)
    +0120     error('geckoLight should be either true or false')
    +0121 end
    +0122 
    +0123 if isempty(modelAdapter)
    +0124     modelAdapter = ModelAdapterManager.getDefault();
    +0125     if isempty(modelAdapter)
    +0126         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0127     end
    +0128 end
    +0129 params = modelAdapter.getParameters();
    +0130 compartmentID = strcmp(model.compNames,params.enzyme_comp);
    +0131 if ~any(compartmentID)
    +0132     error(['Compartment ' params.enzyme_comp ' (specified in params.enzyme_comp) '...
    +0133            'cannot be found in model.compNames'])
    +0134 end
    +0135 compartmentID = model.comps(compartmentID);
    +0136 
    +0137 if geckoLight
    +0138     ec.geckoLight=true;
    +0139 else
    +0140     ec.geckoLight=false;
    +0141 end
    +0142 
    +0143 %Check if model is in RAVEN format
    +0144 if any(isfield(model,{'rules','modelID'}))
    +0145     error(['The model is likely loaded using COBRA Toolbox readCbModel(). Instead, use ' ...
    +0146            'RAVEN Toolbox importModel(). Alternatively, you can also convert the ', ...
    +0147            'model in MATLAB using ravenCobraWrapper().'])
    +0148 end
    +0149 
    +0150 %Check for conflicting reaction and metabolite identifiers
    +0151 conflictId = startsWith(model.mets,'prot_');
    +0152 if any(conflictId)
    +0153     error('The identifiers in model.mets are not allowed to start with ''prot_''.')
    +0154 end
    +0155 conflictId = startsWith(model.rxns,{'usage_prot_','prot_pool'}) | ...
    +0156              endsWith(model.rxns,'_REV') | ...
    +0157              ~cellfun(@isempty,regexp(model.rxns,'_EXP_\d+$'));
    +0158 if any(conflictId)
    +0159     error(['The identifiers in model.rxns are not allowed to start with ''usage_prot'' ' ...
    +0160            'or ''prot_pool'', or end with ''_REV'' or ''_EXP_[digit]''.'])
    +0161 end
    +0162 
    +0163 databases = loadDatabases('both', modelAdapter);
    +0164 uniprotDB = databases.uniprot;
    +0165 keggDB    = databases.kegg;
    +0166 
    +0167 %1: Remove gene rules from pseudoreactions (if any):
    +0168 if exist(fullfile(params.path,'data','pseudoRxns.tsv'),'file')
    +0169     fID        = fopen(fullfile(params.path,'data','pseudoRxns.tsv'));
    +0170     fileData   = textscan(fID,'%s %s','delimiter','\t');
    +0171     fclose(fID);
    +0172     pseudoRxns = fileData{1};
    +0173     pseudoRxns = ismember(model.rxns,pseudoRxns);
    +0174 else
    +0175     pseudoRxns = false(numel(model.rxns),1);
    +0176 end
    +0177 pseudoRxns = find(pseudoRxns | contains(model.rxnNames,'pseudoreaction'));
    +0178 model.grRules(pseudoRxns)       = {''};
    +0179 model.rxnGeneMat(pseudoRxns,:)  = zeros(numel(pseudoRxns), numel(model.genes));
    +0180 
    +0181 %2: Swap direction of reactions that are defined to only carry negative flux
    +0182 to_swap=model.lb < 0 & model.ub == 0;
    +0183 model.S(:,to_swap)=-model.S(:,to_swap);
    +0184 model.ub(to_swap)=-model.lb(to_swap);
    +0185 model.lb(to_swap)=0;
    +0186 
    +0187 %3: Correct rev vector: true if LB < 0 & UB > 0, or it is an exchange reaction:
    +0188 model.rev = false(size(model.rxns));
    +0189 for i = 1:length(model.rxns)
    +0190     if (model.lb(i) < 0 && model.ub(i) > 0) || sum(model.S(:,i) ~= 0) == 1
    +0191         model.rev(i) = true;
    +0192     end
    +0193 end
    +0194 
    +0195 %4: Make irreversible model (appends _REV to reaction IDs to indicate reverse
    +0196 %reactions)
    +0197 [~,exchRxns] = getExchangeRxns(model);
    +0198 nonExchRxns = model.rxns;
    +0199 nonExchRxns(exchRxns) = [];
    +0200 model=convertToIrrev(model, nonExchRxns);
    +0201 
    +0202 %5: Expand model, to separate isozymes (appends _EXP_* to reaction IDs to
    +0203 %indicate duplication)
    +0204 if ~geckoLight
    +0205     model=expandModel(model);
    +0206 end
    +0207 % Sort reactions, so that reversible and isozymic reactions are kept near
    +0208 if ~geckoLight
    +0209     model=sortIdentifiers(model);
    +0210 end
    +0211 
    +0212 %6: Make ec-extension structure, one for gene-associated reaction.
    +0213 %   The structure is different for light and full models
    +0214 rxnWithGene  = find(sum(model.rxnGeneMat,2));
    +0215 if ~geckoLight
    +0216     ec.rxns      = model.rxns(rxnWithGene);
    +0217     emptyCell    = cell(numel(rxnWithGene),1);
    +0218     emptyCell(:) = {''};
    +0219     emptyVect    = zeros(numel(rxnWithGene),1);
    +0220     
    +0221     ec.kcat      = emptyVect;
    +0222     ec.source    = emptyCell; % Strings, like 'dlkcat', 'manual', 'brenda', etc.
    +0223     ec.notes     = emptyCell; % Additional comments
    +0224     ec.eccodes   = emptyCell;
    +0225     ec.concs     = emptyVect;
    +0226 else
    +0227     %Different strategy for GECKO light: Each reaction can exist multiple times in
    +0228     %ec.rxns and similar fields - one time per isozyme. The number of copies is
    +0229     %the number of AND-clauses of the GPR in disjunctive normal form, so
    +0230     %'G1 and (G2 or G3)' gives the isozymes {G1,G2} and {G1,G3}.
    +0231     isozymes = cellfun(@gprToDnf, model.grRules(rxnWithGene), 'UniformOutput', false);
    +0232     % A reaction with gene entries but an empty rule keeps one isozyme without enzymes
    +0233     isozymes(cellfun(@isempty,isozymes)) = {{cell(1,0)}};
    +0234     cpys = cellfun(@numel, isozymes);
    +0235     prevNumRxns = numel(isozymes);
    +0236     cpyIndices = repelem(rxnWithGene, cpys).'; %.' only matter when number of rxns is 1
    +0237     %loop through and add a prefix with an isozyme index to the rxns
    +0238     %we just give a fixed-length number as prefix, and assume that 999 is enough
    +0239     tmpRxns = model.rxns(cpyIndices); %now they have no prefix
    +0240     newRxns = tmpRxns;
    +0241     
    +0242     %add the prefix
    +0243     nextIndex = 1;
    +0244     for i = 1:numel(model.rxns)
    +0245         localRxnIndex = 1;
    +0246         if nextIndex <= length(tmpRxns) && strcmp(model.rxns(i), tmpRxns(nextIndex))
    +0247             while true
    +0248                 tmp = compose('%03d_',localRxnIndex);
    +0249                 newRxns{nextIndex} = [tmp{1} tmpRxns{nextIndex}];
    +0250                 localRxnIndex = localRxnIndex + 1;
    +0251                 if (localRxnIndex >= 1000)
    +0252                     error('Increase index size to 10000 - error in the code.'); %this should never happen, we don't have > 999 isozymes
    +0253                 end
    +0254                 nextIndex = nextIndex + 1;
    +0255                 if  nextIndex > length(tmpRxns) || ~strcmp(model.rxns(i), tmpRxns(nextIndex))
    +0256                     break;
    +0257                 end
    +0258             end
    +0259         end
    +0260     end
    +0261 
    +0262     ec.rxns      = newRxns;
    +0263     
    +0264     emptyCell    = cell(numel(ec.rxns),1);
    +0265     emptyCell(:) = {''};
    +0266     emptyVect    = zeros(numel(ec.rxns),1);
    +0267 
    +0268     ec.kcat      = emptyVect;
    +0269     ec.source    = emptyCell; % Strings, like 'dlkcat', 'manual', 'brenda', etc.
    +0270     ec.notes     = emptyCell; % Additional comments
    +0271     ec.eccodes   = emptyCell;
    +0272     ec.concs     = emptyVect;
    +0273 end
    +0274     
    +0275 %7: Gather enzyme information via UniprotDB (with optional KEGG fallback)
    +0276 uniprotCompatibleGenes = modelAdapter.getUniprotCompatibleGenes(model.genes);
    +0277 [Lia,Locb] = ismember(uniprotCompatibleGenes,uniprotDB.genes);
    +0278 
    +0279 uniprot = modelAdapter.getUniprotIDsFromTable(uniprotCompatibleGenes);
    +0280 if ~isequal(uniprot,uniprotCompatibleGenes)
    +0281     uniprot(cellfun(@isempty,uniprot)) = {''};
    +0282     [Lia,Locb] = ismember(uniprot,uniprotDB.ID);
    +0283 end
    +0284 
    +0285 %KEGG fallback for genes UniProt could not match.
    +0286 keggMatched = false(numel(model.genes),1);
    +0287 keggIdx     = zeros(numel(model.genes),1);
    +0288 if ~isempty(keggDB) && any(~Lia)
    +0289     notLia              = find(~Lia);
    +0290     keggCompatibleGenes = modelAdapter.getKeggCompatibleGenes(model.genes(notLia));
    +0291     [keggHit, kLocb]    = ismember(keggCompatibleGenes,keggDB.genes);
    +0292     keggMatched(notLia(keggHit)) = true;
    +0293     keggIdx(notLia(keggHit))     = kLocb(keggHit);
    +0294 end
    +0295 
    +0296 %noUniprot is now: gene unmatched in both UniProt and KEGG.
    +0297 noUniprot = uniprotCompatibleGenes(~Lia & ~keggMatched);
    +0298 if all(~Lia & ~keggMatched)
    +0299     error('None of the proteins in uniprot.tsv or kegg.tsv match the genes in the model. Changes to the obj.params.uniprot / obj.params.kegg parameters, or a data/uniprotConversion.tsv file are likely required.')
    +0300 elseif ~isempty(noUniprot)
    +0301     printOrange(['WARNING: The ' num2str(numel(noUniprot)) ' gene(s) reported '...
    +0302         'in "noUniprot" cannot be found in data/uniprot.tsv or data/kegg.tsv, these will ' ...
    +0303         'not be enzyme-constrained. If you intend to use different Uniprot '...
    +0304         'data (e.g. from a different proteome, make sure you first delete '...
    +0305         'the existing data/uniprot.tsv file.\n']);
    +0306 end
    +0307 
    +0308 %Build the per-gene enzyme/MW/sequence arrays in two passes: (a)
    +0309 %UniProt-matched, (b) KEGG-fallback-matched. Then concatenate and sort
    +0310 %alphabetically so ec.genes has a stable order across runs.
    +0311 ecGenesUni  = model.genes(Lia); %Will often be duplicate of model.genes, but is done here to prevent issues when it is not.
    +0312 LocbUni     = Locb(Lia);
    +0313 enzUni      = uniprotDB.ID(LocbUni);
    +0314 mwUni       = uniprotDB.MW(LocbUni);
    +0315 seqUni      = uniprotDB.seq(LocbUni);
    +0316 
    +0317 ecGenesKegg = model.genes(keggMatched);
    +0318 LocbKegg    = keggIdx(keggMatched);
    +0319 if isempty(LocbKegg)
    +0320     enzKegg = {};
    +0321     mwKegg  = [];
    +0322     seqKegg = {};
    +0323 else
    +0324     %ec.enzymes gets the UniProt accession stored on the KEGG row; if
    +0325     %that is empty, fall back to the bare KEGG gene id.
    +0326     enzKegg = keggDB.uniprot(LocbKegg);
    +0327     keggFallback = cellfun(@isempty,enzKegg);
    +0328     enzKegg(keggFallback) = keggDB.keggGene(LocbKegg(keggFallback));
    +0329     mwKegg  = keggDB.MW(LocbKegg);
    +0330     seqKegg = keggDB.seq(LocbKegg);
    +0331     if any(keggFallback)
    +0332         fallbackGenes = ecGenesKegg(keggFallback);
    +0333         fallbackIDs   = enzKegg(keggFallback);
    +0334         previewN = min(numel(fallbackGenes),10);
    +0335         previewParts = cell(1,previewN);
    +0336         for ii = 1:previewN
    +0337             previewParts{ii} = [fallbackGenes{ii} '->' fallbackIDs{ii}];
    +0338         end
    +0339         more = '';
    +0340         if numel(fallbackGenes) > 10
    +0341             more = [' (and ' num2str(numel(fallbackGenes)-10) ' more)'];
    +0342         end
    +0343         printOrange(['WARNING: ' num2str(numel(fallbackGenes)) ...
    +0344             ' KEGG-resolved gene(s) had no UniProt accession on the KEGG '...
    +0345             'row; the bare KEGG gene id is used in ec.enzymes instead: '...
    +0346             strjoin(previewParts,', ') more '\n']);
    +0347     end
    +0348 end
    +0349 
    +0350 allGenes   = [ecGenesUni; ecGenesKegg];
    +0351 allEnzymes = [enzUni; enzKegg];
    +0352 allMW      = [mwUni; mwKegg];
    +0353 allSeq     = [seqUni; seqKegg];
    +0354 
    +0355 [ec.genes,sIdx] = sort(allGenes);
    +0356 ec.enzymes      = allEnzymes(sIdx);
    +0357 ec.mw           = allMW(sIdx);
    +0358 ec.sequence     = allSeq(sIdx);
    +0359 %Additional info
    +0360 ec.concs        = nan(numel(ec.genes),1); % To be filled with proteomics data when available
    +0361 
    +0362 %8: Only parse rxns associated to genes
    +0363 if ~geckoLight
    +0364     ec.rxnEnzMat = zeros(numel(rxnWithGene),numel(ec.genes)); % Non-zeros will indicate the number of subunits
    +0365     for r=1:numel(rxnWithGene)
    +0366         rxnGenes   = model.genes(find(model.rxnGeneMat(rxnWithGene(r),:)));
    +0367         [~,locEnz] = ismember(rxnGenes,ec.genes); % Could also parse directly from rxnGeneMat, but some genes might be missing from Uniprot DB
    +0368         locEnz = locEnz(locEnz ~= 0); % Subunits missing from the databases are left out; the others still couple the reaction
    +0369         ec.rxnEnzMat(r,locEnz) = 1; %Assume 1 copy per subunit or enzyme, can be modified later
    +0370     end
    +0371 else
    +0372     %For light models, we need to split up all GPRs
    +0373     ec.rxnEnzMat = zeros(numel(ec.rxns),numel(ec.genes)); % Non-zeros will indicate the number of subunits
    +0374     nextIndex = 1;
    +0375     for i=1:prevNumRxns
    +0376         %Each isozyme is one AND-clause of the GPR and gets its own row of
    +0377         %ec.rxnEnzMat, in the order of the copies of the reaction in ec.rxns.
    +0378         for j = 1:numel(isozymes{i})
    +0379             ec.rxnEnzMat(nextIndex,ismember(ec.genes,isozymes{i}{j})) = 1;%should be subunit stoichoimetry
    +0380             nextIndex = nextIndex + 1;
    +0381         end
    +0382     end
    +0383 end
    +0384 
    +0385 %9: Add proteins as pseudometabolites
    +0386 if ~geckoLight
    +0387     [proteinMets.mets, uniprotSortId] = unique(ec.enzymes);
    +0388     proteinMets.mets         = strcat('prot_',proteinMets.mets);
    +0389     proteinMets.metNames     = proteinMets.mets;
    +0390     proteinMets.compartments = compartmentID;
    +0391     if isfield(model,'metMiriams')
    +0392         proteinMets.metMiriams   = repmat({struct('name',{{'sbo'}},'value',{{'SBO:0000252'}})},numel(proteinMets.mets),1);
    +0393     end
    +0394     if isfield(model,'metCharges')
    +0395         proteinMets.metCharges   = zeros(numel(proteinMets.mets),1);
    +0396     end
    +0397     proteinMets.metNotes     = repmat({'Enzyme-usage pseudometabolite'},numel(proteinMets.mets),1);
    +0398     model = addMets(model,proteinMets);
    +0399 end
    +0400 
    +0401 %10: Add protein pool pseudometabolite
    +0402 pool.mets         = 'prot_pool';
    +0403 pool.metNames     = pool.mets;
    +0404 pool.compartments = compartmentID;
    +0405 pool.metNotes     = 'Enzyme-usage protein pool';
    +0406 model = addMets(model,pool);
    +0407 
    +0408 %11: Add protein usage reactions.
    +0409 % Match the model's own subSystems convention (a cell array of chars, or a
    +0410 % cell array of cell arrays of chars -- RAVEN's checkModelStruct requires
    +0411 % the whole field to be consistently one or the other) rather than always
    +0412 % assuming one shape: mixing the two here is what left new ecModels unable
    +0413 % to be saved once RAVEN's own reconciliation in addRxns stopped papering
    +0414 % over the mismatch.
    +0415 if isfield(model,'subSystems') && ~isempty(model.subSystems) && ...
    +0416         ~any(cellfun(@iscell,model.subSystems))
    +0417     protUsageSubSystem = {'Protein usage'};
    +0418 else
    +0419     protUsageSubSystem = {{'Protein usage'}};
    +0420 end
    +0421 if ~geckoLight
    +0422     rxnNum                    = numel(proteinMets.mets);
    +0423     usageRxns.rxns            = strcat('usage_',proteinMets.mets);
    +0424     usageRxns.rxnNames        = usageRxns.rxns;
    +0425     usageRxns.mets            = cell(rxnNum,1);
    +0426     usageRxns.stoichCoeffs    = cell(rxnNum,1);
    +0427     for i=1:numel(usageRxns.mets)
    +0428         usageRxns.mets{i}         = {proteinMets.mets{i}, 'prot_pool'};
    +0429         usageRxns.stoichCoeffs{i} = [1,-1];
    +0430     end
    +0431     usageRxns.lb              = zeros(rxnNum,1);
    +0432     usageRxns.ub              = zeros(rxnNum,1) + 1000;
    +0433     usageRxns.rev             = ones(rxnNum,1);
    +0434     usageRxns.grRules         = ec.genes(uniprotSortId);
    +0435     if isfield(model,'subSystems')
    +0436         usageRxns.subSystems  = repmat(protUsageSubSystem, rxnNum, 1);
    +0437     end
    +0438     model = addRxns(model,usageRxns);
    +0439 end
    +0440 
    +0441 %12: Add protein pool reaction (forward: -> prot_pool; UB set by setProtPoolSize)
    +0442 poolRxn.rxns            = 'prot_pool_exchange';
    +0443 poolRxn.rxnNames        = poolRxn.rxns;
    +0444 poolRxn.mets            = {'prot_pool'};
    +0445 poolRxn.stoichCoeffs    = {1};
    +0446 poolRxn.lb              = 0;
    +0447 poolRxn.ub              = 1000;
    +0448 poolRxn.rev             = 1;
    +0449 if isfield(model,'subSystems')
    +0450     poolRxn.subSystems  = protUsageSubSystem;
    +0451 end
    +0452 model = addRxns(model,poolRxn);
    +0453 
    +0454 model.ec=ec;
    +0455 end
    +0456 
    +0457 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0458 %Function that expands a gene rule into disjunctive normal form: a cell array
    +0459 %with one cell per isozyme, each holding the gene ids that are ANDed in it.
    +0460 %Gene ids are whole words, so an id that contains 'or' or 'and' is kept
    +0461 %intact. An empty rule gives an empty cell array.
    +0462 function dnf = gprToDnf(rule)
    +0463 tokens = regexp(rule,'\(|\)|[^\s()]+','match');
    +0464 isOperator = strcmpi(tokens,'and') | strcmpi(tokens,'or');
    +0465 tokens(isOperator) = lower(tokens(isOperator)); % Operators are case insensitive
    +0466 if isempty(tokens)
    +0467     dnf = {};
    +0468     return
    +0469 end
    +0470 [dnf,pos] = parseOr(tokens,1,rule);
    +0471 if pos <= numel(tokens)
    +0472     error('Cannot parse the gene rule "%s"',rule)
    +0473 end
    +0474 end
    +0475 
    +0476 function [dnf,pos] = parseOr(tokens,pos,rule)
    +0477 [dnf,pos] = parseAnd(tokens,pos,rule);
    +0478 while pos <= numel(tokens) && strcmp(tokens{pos},'or')
    +0479     [rhs,pos] = parseAnd(tokens,pos+1,rule);
    +0480     dnf = [dnf,rhs];
    +0481 end
    +0482 end
    +0483 
    +0484 function [dnf,pos] = parseAnd(tokens,pos,rule)
    +0485 [dnf,pos] = parseAtom(tokens,pos,rule);
    +0486 while pos <= numel(tokens) && strcmp(tokens{pos},'and')
    +0487     [rhs,pos] = parseAtom(tokens,pos+1,rule);
    +0488     product = cell(1,0);
    +0489     for a = 1:numel(dnf)
    +0490         for b = 1:numel(rhs)
    +0491             product{end+1} = [dnf{a},rhs{b}]; %#ok<AGROW>
    +0492         end
    +0493     end
    +0494     dnf = product;
    +0495 end
    +0496 end
    +0497 
    +0498 function [dnf,pos] = parseAtom(tokens,pos,rule)
    +0499 if pos > numel(tokens) || any(strcmp(tokens{pos},{')','and','or'}))
    +0500     error('Cannot parse the gene rule "%s"',rule)
    +0501 elseif strcmp(tokens{pos},'(')
    +0502     [dnf,pos] = parseOr(tokens,pos+1,rule);
    +0503     if pos > numel(tokens) || ~strcmp(tokens{pos},')')
    +0504         error('Cannot parse the gene rule "%s"',rule)
    +0505     end
    +0506     pos = pos + 1;
    +0507 else
    +0508     dnf = {tokens(pos)};
    +0509     pos = pos + 1;
    +0510 end
    +0511 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/mapRxnsToConv.html b/doc/src/change_model/mapRxnsToConv.html new file mode 100644 index 00000000..f8769bc1 --- /dev/null +++ b/doc/src/change_model/mapRxnsToConv.html @@ -0,0 +1,151 @@ + + + + Description of mapRxnsToConv + + + + + + + + + +
    Home > src > change_model > mapRxnsToConv.m
    + + + +

    mapRxnsToConv +

    + +

    PURPOSE ^

    +
    mapRxnsToConv Map ecModel fluxes back to the conventional starting model.
    + +

    SYNOPSIS ^

    +
    function [mappedFlux, enzUsageFlux, usageEnz] = mapRxnsToConv(ecModel, model, fluxVect)
    + +

    DESCRIPTION ^

    +
     mapRxnsToConv  Map ecModel fluxes back to the conventional starting model.
    +
    + A vector (or matrix) of fluxes is mapped to the reactions in the
    + conventional starting model that was used to construct the ecModel. It is
    + essential that the provided conventional model is indeed the model that
    + was used to initiate ecModel reconstruction.
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure), that was
    +     used to obtain fluxVect.
    + model : struct
    +     the starting model for ecModel, to which the reactions should be
    +     mapped.
    + fluxVect : double
    +     vector or matrix of flux values, matching ecModel.rxns.
    +
    + Returns
    + -------
    + mappedFlux : double
    +     vector or matrix of flux values, matching model.rxns.
    + enzUsageFlux : double
    +     vector or matrix of flux values from enzyme usage reactions, as these
    +     are absent from mappedFlux.
    + usageEnz : cell
    +     cell array with protein IDs, matching enzUsageFlux.
    +
    + Examples
    + --------
    +     [mappedFlux, enzUsageFlux, usageEnz] = mapRxnsToConv(ecModel, model, fluxVect);
    +
    + See also
    + --------
    + ecFVA
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function [mappedFlux, enzUsageFlux, usageEnz] = mapRxnsToConv(ecModel, model, fluxVect)
    +0002 % mapRxnsToConv  Map ecModel fluxes back to the conventional starting model.
    +0003 %
    +0004 % A vector (or matrix) of fluxes is mapped to the reactions in the
    +0005 % conventional starting model that was used to construct the ecModel. It is
    +0006 % essential that the provided conventional model is indeed the model that
    +0007 % was used to initiate ecModel reconstruction.
    +0008 %
    +0009 % Parameters
    +0010 % ----------
    +0011 % ecModel : struct
    +0012 %     an ecModel in GECKO 3 format (with ecModel.ec structure), that was
    +0013 %     used to obtain fluxVect.
    +0014 % model : struct
    +0015 %     the starting model for ecModel, to which the reactions should be
    +0016 %     mapped.
    +0017 % fluxVect : double
    +0018 %     vector or matrix of flux values, matching ecModel.rxns.
    +0019 %
    +0020 % Returns
    +0021 % -------
    +0022 % mappedFlux : double
    +0023 %     vector or matrix of flux values, matching model.rxns.
    +0024 % enzUsageFlux : double
    +0025 %     vector or matrix of flux values from enzyme usage reactions, as these
    +0026 %     are absent from mappedFlux.
    +0027 % usageEnz : cell
    +0028 %     cell array with protein IDs, matching enzUsageFlux.
    +0029 %
    +0030 % Examples
    +0031 % --------
    +0032 %     [mappedFlux, enzUsageFlux, usageEnz] = mapRxnsToConv(ecModel, model, fluxVect);
    +0033 %
    +0034 % See also
    +0035 % --------
    +0036 % ecFVA
    +0037 
    +0038 if isempty(fluxVect)
    +0039     error('No or empty flux vector provided')
    +0040 end
    +0041 
    +0042 fluxes = fluxVect;
    +0043 rxnIDs = ecModel.rxns;
    +0044 
    +0045 % Invert flux of _REV reactions
    +0046 % The suffixes are added in the order _REV, _EXP_n, so strip _EXP_n first and
    +0047 % then _REV, each only at the end of the id (an id like R_REVX is left intact).
    +0048 rxnIDs = regexprep(rxnIDs,'_EXP_\d+$','');
    +0049 revRxns = endsWith(rxnIDs,'_REV');
    +0050 fluxes(revRxns,:) = -fluxes(revRxns,:);
    +0051 rxnIDs(revRxns) = regexprep(rxnIDs(revRxns),'_REV$','');
    +0052 
    +0053 % Map and sum fluxes to converted reaction IDs
    +0054 [rxnIDmap, convRxnID] = findgroups(rxnIDs);
    +0055 newVect = splitapply(@(x){sum(x,1)}, fluxes, rxnIDmap);
    +0056 newVect = cell2mat(newVect);
    +0057 
    +0058 % Place in same order as in original model
    +0059 [mapCheck,origIdx] = ismember(model.rxns,convRxnID);
    +0060 if ~all(mapCheck)
    +0061     error('Not all reactions from model.rxns can be found in the ecModel. Are you sure that ecModel is derived from model?')
    +0062 end
    +0063 mappedFlux=newVect(origIdx,:);
    +0064 
    +0065 % Separately report enzyme usages
    +0066 usageEnz = startsWith(ecModel.rxns,{'usage_prot_','prot_pool_exchange'});
    +0067 enzUsageFlux = fluxVect(usageEnz,:);
    +0068 usageEnz = regexprep(ecModel.rxns(usageEnz),'usage_prot_','');
    +0069 usageEnz = regexprep(usageEnz,'prot_pool_exchange','pool');
    +0070 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/setKcatForReactions.html b/doc/src/change_model/setKcatForReactions.html new file mode 100644 index 00000000..365fca0b --- /dev/null +++ b/doc/src/change_model/setKcatForReactions.html @@ -0,0 +1,144 @@ + + + + Description of setKcatForReactions + + + + + + + + + +
    Home > src > change_model > setKcatForReactions.m
    + + + +

    setKcatForReactions +

    + +

    PURPOSE ^

    +
    setKcatForReactions Change the kcat value for selected reactions.
    + +

    SYNOPSIS ^

    +
    function ecModel = setKcatForReactions(ecModel,rxnIds,kcat)
    + +

    DESCRIPTION ^

    +
     setKcatForReactions  Change the kcat value for selected reactions.
    +
    + Changes the kcat value in ecModel.ec.kcat for selected reactions.
    + applyKcatConstraints needs to be run afterwards to transfer the kcat
    + values into the S-matrix.
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    + rxnIds : char or cell
    +     reaction identifier matching ecModel.ec.rxns. If the _EXP_ suffix is
    +     not included, and there are multiple expanded (isozymic) reactions,
    +     then all of those will have their kcat changed. If rxnIds includes a
    +     _EXP_ suffix, then only that specific reaction will have its kcat
    +     changed. If multiple rxnIds are provided as a cell array, then the
    +     above applies to each rxnIds individually.
    + kcat : double
    +     the new kcat value.
    +
    + Returns
    + -------
    + ecModel : struct
    +     ecModel where selected kcat values in ecModel.ec.kcat are changed, but
    +     not yet applied to the S-matrix (will require to run
    +     applyKcatConstraints). ecModel.ec.source for the changed reactions
    +     will read 'setKcatForReactions'.
    +
    + Examples
    + --------
    +     ecModel = setKcatForReactions(ecModel, rxnIds, kcat);
    +
    + See also
    + --------
    + applyKcatConstraints, getKcatAcrossIsozymes
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function ecModel = setKcatForReactions(ecModel,rxnIds,kcat)
    +0002 % setKcatForReactions  Change the kcat value for selected reactions.
    +0003 %
    +0004 % Changes the kcat value in ecModel.ec.kcat for selected reactions.
    +0005 % applyKcatConstraints needs to be run afterwards to transfer the kcat
    +0006 % values into the S-matrix.
    +0007 %
    +0008 % Parameters
    +0009 % ----------
    +0010 % ecModel : struct
    +0011 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0012 % rxnIds : char or cell
    +0013 %     reaction identifier matching ecModel.ec.rxns. If the _EXP_ suffix is
    +0014 %     not included, and there are multiple expanded (isozymic) reactions,
    +0015 %     then all of those will have their kcat changed. If rxnIds includes a
    +0016 %     _EXP_ suffix, then only that specific reaction will have its kcat
    +0017 %     changed. If multiple rxnIds are provided as a cell array, then the
    +0018 %     above applies to each rxnIds individually.
    +0019 % kcat : double
    +0020 %     the new kcat value.
    +0021 %
    +0022 % Returns
    +0023 % -------
    +0024 % ecModel : struct
    +0025 %     ecModel where selected kcat values in ecModel.ec.kcat are changed, but
    +0026 %     not yet applied to the S-matrix (will require to run
    +0027 %     applyKcatConstraints). ecModel.ec.source for the changed reactions
    +0028 %     will read 'setKcatForReactions'.
    +0029 %
    +0030 % Examples
    +0031 % --------
    +0032 %     ecModel = setKcatForReactions(ecModel, rxnIds, kcat);
    +0033 %
    +0034 % See also
    +0035 % --------
    +0036 % applyKcatConstraints, getKcatAcrossIsozymes
    +0037 rxnIds = convertCharArray(rxnIds);
    +0038 
    +0039 hasExp       = ~cellfun(@isempty,regexp(rxnIds,'_EXP_\d+$'));
    +0040 nonExpRxns   = regexprep(ecModel.ec.rxns,'_EXP_\d+$','');
    +0041 rxnsToChange = [];
    +0042 for i=1:numel(hasExp)
    +0043     if hasExp(i) == 1
    +0044         rxnsToChange = [rxnsToChange; find(strcmpi(ecModel.ec.rxns,rxnIds{i}))];
    +0045     else
    +0046         nonExpRxn    = regexprep(rxnIds(i),'_EXP_\d+$','');
    +0047         rxnsToChange = [rxnsToChange; find(strcmpi(nonExpRxns,nonExpRxn))];
    +0048     end
    +0049 end
    +0050 if isscalar(rxnsToChange)
    +0051     if length(kcat) ~= 1
    +0052         error('Found one reaction whose kcat should change, you should provide one kcat value only.')
    +0053     end
    +0054 else
    +0055     if isscalar(kcat)
    +0056         % Is fine, all reactions get the same kcat
    +0057     elseif length(kcat) ~= length(rxnsToChange)
    +0058         error('Found %d reactions whose kcat should change, the new kcat should be either a single value, or a vector of length %d.', length(rxnsToChange), length(rxnsToChange))
    +0059     end
    +0060 end
    +0061 ecModel.ec.kcat(rxnsToChange)   = kcat;
    +0062 ecModel.ec.source(rxnsToChange) = {'setKcatForReactions'};
    +0063 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/setProtPoolSize.html b/doc/src/change_model/setProtPoolSize.html new file mode 100644 index 00000000..6cc7a855 --- /dev/null +++ b/doc/src/change_model/setProtPoolSize.html @@ -0,0 +1,154 @@ + + + + Description of setProtPoolSize + + + + + + + + + +
    Home > src > change_model > setProtPoolSize.m
    + + + +

    setProtPoolSize +

    + +

    PURPOSE ^

    +
    setProtPoolSize Set the limit of the total protein usage in the model.
    + +

    SYNOPSIS ^

    +
    function model = setProtPoolSize(model, varargin)
    + +

    DESCRIPTION ^

    +
     setProtPoolSize  Set the limit of the total protein usage in the model.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + Ptot : double
    +     total cellular protein content in g/gDCW. If not specified, the value
    +     will be read from the model adapter. If not specified in model
    +     adapter, 0.5 g/gDCW is assumed.
    + f : double
    +     estimated fraction of enzymes in the model. If not specified, the
    +     value will be read from the model adapter. If not specified in model
    +     adapter, 0.5 is assumed.
    + sigma : double
    +     estimated saturation factor. If not specified, the value will be read
    +     from the model adapter. If not specified in model adapter, 0.5 is
    +     assumed.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + model : struct
    +     ecModel with protein pool constraint set.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     model = setProtPoolSize(model, Ptot, f, sigma, modelAdapter);
    +     model = setProtPoolSize(model, 'Ptot', Ptot);
    +
    + See also
    + --------
    + makeEcModel
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function model = setProtPoolSize(model, varargin)
    +0002 % setProtPoolSize  Set the limit of the total protein usage in the model.
    +0003 %
    +0004 % Parameters
    +0005 % ----------
    +0006 % model : struct
    +0007 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0008 %
    +0009 % Name-Value Arguments
    +0010 % --------------------
    +0011 % Ptot : double
    +0012 %     total cellular protein content in g/gDCW. If not specified, the value
    +0013 %     will be read from the model adapter. If not specified in model
    +0014 %     adapter, 0.5 g/gDCW is assumed.
    +0015 % f : double
    +0016 %     estimated fraction of enzymes in the model. If not specified, the
    +0017 %     value will be read from the model adapter. If not specified in model
    +0018 %     adapter, 0.5 is assumed.
    +0019 % sigma : double
    +0020 %     estimated saturation factor. If not specified, the value will be read
    +0021 %     from the model adapter. If not specified in model adapter, 0.5 is
    +0022 %     assumed.
    +0023 % modelAdapter : ModelAdapter
    +0024 %     a loaded model adapter (default: the current default model adapter).
    +0025 %
    +0026 % Returns
    +0027 % -------
    +0028 % model : struct
    +0029 %     ecModel with protein pool constraint set.
    +0030 %
    +0031 % Examples
    +0032 % --------
    +0033 %     % optional arguments may be given positionally or as name-value pairs:
    +0034 %     model = setProtPoolSize(model, Ptot, f, sigma, modelAdapter);
    +0035 %     model = setProtPoolSize(model, 'Ptot', Ptot);
    +0036 %
    +0037 % See also
    +0038 % --------
    +0039 % makeEcModel
    +0040 
    +0041 p = parseGECKOargs(varargin, { ...
    +0042     'Ptot',         []; ...
    +0043     'f',            []; ...
    +0044     'sigma',        []; ...
    +0045     'modelAdapter', []});
    +0046 Ptot         = p.Ptot;
    +0047 f            = p.f;
    +0048 sigma        = p.sigma;
    +0049 modelAdapter = p.modelAdapter;
    +0050 
    +0051 if isempty(modelAdapter)
    +0052     modelAdapter = ModelAdapterManager.getDefault();
    +0053     if isempty(modelAdapter) && (isempty(Ptot) || isempty(f) || isempty(sigma))
    +0054         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0055     end
    +0056 end
    +0057 
    +0058 if isempty(sigma)
    +0059     sigma = modelAdapter.getParameters().sigma;
    +0060 end
    +0061 if isempty(f)
    +0062     f = modelAdapter.getParameters().f;
    +0063 end
    +0064 if isempty(Ptot)
    +0065     Ptot = modelAdapter.getParameters().Ptot;
    +0066 end
    +0067 
    +0068 model.ub(strcmp(model.rxns, 'prot_pool_exchange')) = Ptot*f*sigma*1000;
    +0069 end
    +0070
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/change_model/upgradeEcModel.html b/doc/src/change_model/upgradeEcModel.html new file mode 100644 index 00000000..7a55cea5 --- /dev/null +++ b/doc/src/change_model/upgradeEcModel.html @@ -0,0 +1,143 @@ + + + + Description of upgradeEcModel + + + + + + + + + +
    Home > src > change_model > upgradeEcModel.m
    + + + +

    upgradeEcModel +

    + +

    PURPOSE ^

    +
    upgradeEcModel Bring an ecModel made with GECKO 3 to the GECKO 4 format.
    + +

    SYNOPSIS ^

    +
    function [model, changed] = upgradeEcModel(model)
    + +

    DESCRIPTION ^

    +
     upgradeEcModel  Bring an ecModel made with GECKO 3 to the GECKO 4 format.
    +
    + GECKO 3 defined the protein usage reactions (usage_prot_<id>, prot_<id>
    + -> prot_pool) and the protein pool exchange (prot_pool_exchange,
    + prot_pool ->) in the reverse direction, used with negative flux. GECKO 4
    + defines them forward (prot_pool -> prot_<id>, -> prot_pool), so that an
    + enzyme's usage is the positive flux of its usage reaction. This turns
    + each reaction that is still reverse: its column of S, its bounds and its
    + objective coefficient change sign. Reactions already forward are left as
    + they are, so calling it again changes nothing. Flux values of the model
    + (fluxes of usage reactions and the pool exchange) change sign with it.
    + The ecModel format (annotation.gecko_format, see saveEcModel) becomes 4
    + when it is missing or lower.
    + geckopy has the same (upgrade_ec_model).
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel.
    +
    + Returns
    + -------
    + model : struct
    +     the ecModel in the GECKO 4 format.
    + changed : cell
    +     the reactions that were turned.
    +
    + Examples
    + --------
    +     ecModel = upgradeEcModel(readYAMLmodel('ecYeastGEM_GECKO3.yml'));
    +
    + See also
    + --------
    + upgradeGECKOproject, makeEcModel, setProtPoolSize
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function [model, changed] = upgradeEcModel(model)
    +0002 % upgradeEcModel  Bring an ecModel made with GECKO 3 to the GECKO 4 format.
    +0003 %
    +0004 % GECKO 3 defined the protein usage reactions (usage_prot_<id>, prot_<id>
    +0005 % -> prot_pool) and the protein pool exchange (prot_pool_exchange,
    +0006 % prot_pool ->) in the reverse direction, used with negative flux. GECKO 4
    +0007 % defines them forward (prot_pool -> prot_<id>, -> prot_pool), so that an
    +0008 % enzyme's usage is the positive flux of its usage reaction. This turns
    +0009 % each reaction that is still reverse: its column of S, its bounds and its
    +0010 % objective coefficient change sign. Reactions already forward are left as
    +0011 % they are, so calling it again changes nothing. Flux values of the model
    +0012 % (fluxes of usage reactions and the pool exchange) change sign with it.
    +0013 % The ecModel format (annotation.gecko_format, see saveEcModel) becomes 4
    +0014 % when it is missing or lower.
    +0015 % geckopy has the same (upgrade_ec_model).
    +0016 %
    +0017 % Parameters
    +0018 % ----------
    +0019 % model : struct
    +0020 %     an ecModel.
    +0021 %
    +0022 % Returns
    +0023 % -------
    +0024 % model : struct
    +0025 %     the ecModel in the GECKO 4 format.
    +0026 % changed : cell
    +0027 %     the reactions that were turned.
    +0028 %
    +0029 % Examples
    +0030 % --------
    +0031 %     ecModel = upgradeEcModel(readYAMLmodel('ecYeastGEM_GECKO3.yml'));
    +0032 %
    +0033 % See also
    +0034 % --------
    +0035 % upgradeGECKOproject, makeEcModel, setProtPoolSize
    +0036 
    +0037 pool = find(strcmp(model.mets, 'prot_pool'));
    +0038 changed = {};
    +0039 if isempty(pool)
    +0040     return
    +0041 end
    +0042 if ~isfield(model, 'annotation') || ~isfield(model.annotation, 'gecko_format') ...
    +0043         || str2double(model.annotation.gecko_format) < 4
    +0044     model.annotation.gecko_format = '4';
    +0045 end
    +0046 usage = find(startsWith(model.rxns, 'usage_prot_'));
    +0047 reverse = usage(full(model.S(pool, usage)) > 0);
    +0048 exchange = find(strcmp(model.rxns, 'prot_pool_exchange'));
    +0049 if ~isempty(exchange) && full(model.S(pool, exchange)) < 0
    +0050     reverse(end+1, 1) = exchange;
    +0051 end
    +0052 if isempty(reverse)
    +0053     return
    +0054 end
    +0055 model.S(:, reverse) = -model.S(:, reverse);
    +0056 lb = model.lb(reverse);
    +0057 model.lb(reverse) = -model.ub(reverse);
    +0058 model.ub(reverse) = -lb;
    +0059 if isfield(model, 'c')
    +0060     model.c(reverse) = -model.c(reverse);
    +0061 end
    +0062 changed = model.rxns(reverse);
    +0063 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/deprecated/addCarbonNum.html b/doc/src/deprecated/addCarbonNum.html new file mode 100644 index 00000000..7abc05d8 --- /dev/null +++ b/doc/src/deprecated/addCarbonNum.html @@ -0,0 +1,68 @@ + + + + Description of addCarbonNum + + + + + + + + + +
    Home > src > deprecated > addCarbonNum.m
    + + + +

    addCarbonNum +

    + +

    PURPOSE ^

    +
    addCarbonNum Deprecated alias for fillCarbonNum.
    + +

    SYNOPSIS ^

    +
    function varargout = addCarbonNum(varargin)
    + +

    DESCRIPTION ^

    +
     addCarbonNum  Deprecated alias for fillCarbonNum.
    +
    + Kept for backward compatibility with pre-GECKO4 code. Will be removed
    + in a future release; switch to fillCarbonNum.
    +
    + See also
    + --------
    + fillCarbonNum
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function varargout = addCarbonNum(varargin)
    +0002 % addCarbonNum  Deprecated alias for fillCarbonNum.
    +0003 %
    +0004 % Kept for backward compatibility with pre-GECKO4 code. Will be removed
    +0005 % in a future release; switch to fillCarbonNum.
    +0006 %
    +0007 % See also
    +0008 % --------
    +0009 % fillCarbonNum
    +0010 
    +0011 warning('GECKO:deprecatedName', ...
    +0012     'addCarbonNum is deprecated; use fillCarbonNum instead. The old name will be removed in a future release.');
    +0013 [varargout{1:nargout}] = fillCarbonNum(varargin{:});
    +0014 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/deprecated/copyECtoGEM.html b/doc/src/deprecated/copyECtoGEM.html new file mode 100644 index 00000000..40d95119 --- /dev/null +++ b/doc/src/deprecated/copyECtoGEM.html @@ -0,0 +1,68 @@ + + + + Description of copyECtoGEM + + + + + + + + + +
    Home > src > deprecated > copyECtoGEM.m
    + + + +

    copyECtoGEM +

    + +

    PURPOSE ^

    +
    copyECtoGEM Deprecated alias for applyECcodes.
    + +

    SYNOPSIS ^

    +
    function varargout = copyECtoGEM(varargin)
    + +

    DESCRIPTION ^

    +
     copyECtoGEM  Deprecated alias for applyECcodes.
    +
    + Kept for backward compatibility with pre-GECKO4 code. Will be removed
    + in a future release; switch to applyECcodes.
    +
    + See also
    + --------
    + applyECcodes
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function varargout = copyECtoGEM(varargin)
    +0002 % copyECtoGEM  Deprecated alias for applyECcodes.
    +0003 %
    +0004 % Kept for backward compatibility with pre-GECKO4 code. Will be removed
    +0005 % in a future release; switch to applyECcodes.
    +0006 %
    +0007 % See also
    +0008 % --------
    +0009 % applyECcodes
    +0010 
    +0011 warning('GECKO:deprecatedName', ...
    +0012     'copyECtoGEM is deprecated; use applyECcodes instead. The old name will be removed in a future release.');
    +0013 [varargout{1:nargout}] = applyECcodes(varargin{:});
    +0014 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/deprecated/enzymeUsage.html b/doc/src/deprecated/enzymeUsage.html new file mode 100644 index 00000000..e68be605 --- /dev/null +++ b/doc/src/deprecated/enzymeUsage.html @@ -0,0 +1,68 @@ + + + + Description of enzymeUsage + + + + + + + + + +
    Home > src > deprecated > enzymeUsage.m
    + + + +

    enzymeUsage +

    + +

    PURPOSE ^

    +
    enzymeUsage Deprecated alias for getEnzymeUsage.
    + +

    SYNOPSIS ^

    +
    function varargout = enzymeUsage(varargin)
    + +

    DESCRIPTION ^

    +
     enzymeUsage  Deprecated alias for getEnzymeUsage.
    +
    + Kept for backward compatibility with pre-GECKO4 code. Will be removed
    + in a future release; switch to getEnzymeUsage.
    +
    + See also
    + --------
    + getEnzymeUsage
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function varargout = enzymeUsage(varargin)
    +0002 % enzymeUsage  Deprecated alias for getEnzymeUsage.
    +0003 %
    +0004 % Kept for backward compatibility with pre-GECKO4 code. Will be removed
    +0005 % in a future release; switch to getEnzymeUsage.
    +0006 %
    +0007 % See also
    +0008 % --------
    +0009 % getEnzymeUsage
    +0010 
    +0011 warning('GECKO:deprecatedName', ...
    +0012     'enzymeUsage is deprecated; use getEnzymeUsage instead. The old name will be removed in a future release.');
    +0013 [varargout{1:nargout}] = getEnzymeUsage(varargin{:});
    +0014 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/deprecated/index.html b/doc/src/deprecated/index.html new file mode 100644 index 00000000..9ecdc7c3 --- /dev/null +++ b/doc/src/deprecated/index.html @@ -0,0 +1,29 @@ + + + + Index for Directory src/deprecated + + + + + + + + + + +
    < Master indexIndex for src/deprecated >
    + +

    Index for src/deprecated

    + +

    Matlab files in this directory:

    + +
     addCarbonNumaddCarbonNum Deprecated alias for fillCarbonNum.
     copyECtoGEMcopyECtoGEM Deprecated alias for applyECcodes.
     enzymeUsageenzymeUsage Deprecated alias for getEnzymeUsage.
     pfbaEnzymespfbaEnzymes Deprecated alias for getPfbaEnzymes.
     selectKcatValueselectKcatValue Deprecated alias for assignKcatValues.
     startGECKOprojectstartGECKOproject Deprecated alias for createGECKOproject.
     updateGECKOdocupdateGECKOdoc Deprecated alias for buildGECKOdoc.
    + + + + +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/deprecated/pfbaEnzymes.html b/doc/src/deprecated/pfbaEnzymes.html new file mode 100644 index 00000000..b0ffb15b --- /dev/null +++ b/doc/src/deprecated/pfbaEnzymes.html @@ -0,0 +1,68 @@ + + + + Description of pfbaEnzymes + + + + + + + + + +
    Home > src > deprecated > pfbaEnzymes.m
    + + + +

    pfbaEnzymes +

    + +

    PURPOSE ^

    +
    pfbaEnzymes Deprecated alias for getPfbaEnzymes.
    + +

    SYNOPSIS ^

    +
    function varargout = pfbaEnzymes(varargin)
    + +

    DESCRIPTION ^

    +
     pfbaEnzymes  Deprecated alias for getPfbaEnzymes.
    +
    + Kept for backward compatibility with pre-GECKO4 code. Will be removed
    + in a future release; switch to getPfbaEnzymes.
    +
    + See also
    + --------
    + getPfbaEnzymes
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function varargout = pfbaEnzymes(varargin)
    +0002 % pfbaEnzymes  Deprecated alias for getPfbaEnzymes.
    +0003 %
    +0004 % Kept for backward compatibility with pre-GECKO4 code. Will be removed
    +0005 % in a future release; switch to getPfbaEnzymes.
    +0006 %
    +0007 % See also
    +0008 % --------
    +0009 % getPfbaEnzymes
    +0010 
    +0011 warning('GECKO:deprecatedName', ...
    +0012     'pfbaEnzymes is deprecated; use getPfbaEnzymes instead. The old name will be removed in a future release.');
    +0013 [varargout{1:nargout}] = getPfbaEnzymes(varargin{:});
    +0014 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/deprecated/selectKcatValue.html b/doc/src/deprecated/selectKcatValue.html new file mode 100644 index 00000000..b7650aad --- /dev/null +++ b/doc/src/deprecated/selectKcatValue.html @@ -0,0 +1,68 @@ + + + + Description of selectKcatValue + + + + + + + + + +
    Home > src > deprecated > selectKcatValue.m
    + + + +

    selectKcatValue +

    + +

    PURPOSE ^

    +
    selectKcatValue Deprecated alias for assignKcatValues.
    + +

    SYNOPSIS ^

    +
    function varargout = selectKcatValue(varargin)
    + +

    DESCRIPTION ^

    +
     selectKcatValue  Deprecated alias for assignKcatValues.
    +
    + Kept for backward compatibility with pre-GECKO4 code. Will be removed
    + in a future release; switch to assignKcatValues.
    +
    + See also
    + --------
    + assignKcatValues
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function varargout = selectKcatValue(varargin)
    +0002 % selectKcatValue  Deprecated alias for assignKcatValues.
    +0003 %
    +0004 % Kept for backward compatibility with pre-GECKO4 code. Will be removed
    +0005 % in a future release; switch to assignKcatValues.
    +0006 %
    +0007 % See also
    +0008 % --------
    +0009 % assignKcatValues
    +0010 
    +0011 warning('GECKO:deprecatedName', ...
    +0012     'selectKcatValue is deprecated; use assignKcatValues instead. The old name will be removed in a future release.');
    +0013 [varargout{1:nargout}] = assignKcatValues(varargin{:});
    +0014 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/deprecated/startGECKOproject.html b/doc/src/deprecated/startGECKOproject.html new file mode 100644 index 00000000..53614657 --- /dev/null +++ b/doc/src/deprecated/startGECKOproject.html @@ -0,0 +1,68 @@ + + + + Description of startGECKOproject + + + + + + + + + +
    Home > src > deprecated > startGECKOproject.m
    + + + +

    startGECKOproject +

    + +

    PURPOSE ^

    +
    startGECKOproject Deprecated alias for createGECKOproject.
    + +

    SYNOPSIS ^

    +
    function varargout = startGECKOproject(varargin)
    + +

    DESCRIPTION ^

    +
     startGECKOproject  Deprecated alias for createGECKOproject.
    +
    + Kept for backward compatibility with pre-GECKO4 code. Will be removed
    + in a future release; switch to createGECKOproject.
    +
    + See also
    + --------
    + createGECKOproject
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function varargout = startGECKOproject(varargin)
    +0002 % startGECKOproject  Deprecated alias for createGECKOproject.
    +0003 %
    +0004 % Kept for backward compatibility with pre-GECKO4 code. Will be removed
    +0005 % in a future release; switch to createGECKOproject.
    +0006 %
    +0007 % See also
    +0008 % --------
    +0009 % createGECKOproject
    +0010 
    +0011 warning('GECKO:deprecatedName', ...
    +0012     'startGECKOproject is deprecated; use createGECKOproject instead. The old name will be removed in a future release.');
    +0013 [varargout{1:nargout}] = createGECKOproject(varargin{:});
    +0014 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/deprecated/updateGECKOdoc.html b/doc/src/deprecated/updateGECKOdoc.html new file mode 100644 index 00000000..b6a6aad3 --- /dev/null +++ b/doc/src/deprecated/updateGECKOdoc.html @@ -0,0 +1,68 @@ + + + + Description of updateGECKOdoc + + + + + + + + + +
    Home > src > deprecated > updateGECKOdoc.m
    + + + +

    updateGECKOdoc +

    + +

    PURPOSE ^

    +
    updateGECKOdoc Deprecated alias for buildGECKOdoc.
    + +

    SYNOPSIS ^

    +
    function varargout = updateGECKOdoc(varargin)
    + +

    DESCRIPTION ^

    +
     updateGECKOdoc  Deprecated alias for buildGECKOdoc.
    +
    + Kept for backward compatibility with pre-GECKO4 code. Will be removed
    + in a future release; switch to buildGECKOdoc.
    +
    + See also
    + --------
    + buildGECKOdoc
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function varargout = updateGECKOdoc(varargin)
    +0002 % updateGECKOdoc  Deprecated alias for buildGECKOdoc.
    +0003 %
    +0004 % Kept for backward compatibility with pre-GECKO4 code. Will be removed
    +0005 % in a future release; switch to buildGECKOdoc.
    +0006 %
    +0007 % See also
    +0008 % --------
    +0009 % buildGECKOdoc
    +0010 
    +0011 warning('GECKO:deprecatedName', ...
    +0012     'updateGECKOdoc is deprecated; use buildGECKOdoc instead. The old name will be removed in a future release.');
    +0013 [varargout{1:nargout}] = buildGECKOdoc(varargin{:});
    +0014 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/download_databases/downloadKEGG.html b/doc/src/download_databases/downloadKEGG.html new file mode 100644 index 00000000..781f34eb --- /dev/null +++ b/doc/src/download_databases/downloadKEGG.html @@ -0,0 +1,222 @@ + + + + Description of downloadKEGG + + + + + + + + + +
    Home > src > download_databases > downloadKEGG.m
    + + + +

    downloadKEGG +

    + +

    PURPOSE ^

    +
    downloadKEGG Download a KEGG organism's gene data and write a CSV.
    + +

    SYNOPSIS ^

    +
    function downloadKEGG(keggID, filePath, keggGeneID)
    + +

    DESCRIPTION ^

    +
     downloadKEGG  Download a KEGG organism's gene data and write a CSV.
    +
    + Downloads gene information for every gene of a KEGG organism code, and
    + writes the result to a CSV file. Used by loadDatabases when its
    + expected kegg.tsv is missing; can also be called directly to refresh
    + one organism's KEGG snapshot without re-running loadDatabases for
    + everything else.
    +
    + Parameters
    + ----------
    + keggID : char
    +     KEGG organism code, e.g. 'sce' for Saccharomyces cerevisiae.
    + filePath : char
    +     destination CSV path (overwritten if it exists).
    + keggGeneID : char
    +     which KEGG gene identifier field becomes the output's gene-name
    +     column. 'kegg' (or empty, the default) uses the bare KEGG gene id;
    +     any other value is looked up as a cross-reference identifier on
    +     each KEGG entry (e.g. 'UniProt').
    +
    + Examples
    + --------
    +     downloadKEGG('sce', 'kegg.tsv', 'UniProt');
    +
    + See also
    + --------
    + loadDatabases, downloadUniProt
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • loadDatabases loadDatabases Load the organism-specific KEGG and UniProt databases.
    + + + + +

    SOURCE CODE ^

    +
    0001 function downloadKEGG(keggID, filePath, keggGeneID)
    +0002 % downloadKEGG  Download a KEGG organism's gene data and write a CSV.
    +0003 %
    +0004 % Downloads gene information for every gene of a KEGG organism code, and
    +0005 % writes the result to a CSV file. Used by loadDatabases when its
    +0006 % expected kegg.tsv is missing; can also be called directly to refresh
    +0007 % one organism's KEGG snapshot without re-running loadDatabases for
    +0008 % everything else.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % keggID : char
    +0013 %     KEGG organism code, e.g. 'sce' for Saccharomyces cerevisiae.
    +0014 % filePath : char
    +0015 %     destination CSV path (overwritten if it exists).
    +0016 % keggGeneID : char
    +0017 %     which KEGG gene identifier field becomes the output's gene-name
    +0018 %     column. 'kegg' (or empty, the default) uses the bare KEGG gene id;
    +0019 %     any other value is looked up as a cross-reference identifier on
    +0020 %     each KEGG entry (e.g. 'UniProt').
    +0021 %
    +0022 % Examples
    +0023 % --------
    +0024 %     downloadKEGG('sce', 'kegg.tsv', 'UniProt');
    +0025 %
    +0026 % See also
    +0027 % --------
    +0028 % loadDatabases, downloadUniProt
    +0029 
    +0030 if nargin < 3 || isempty(keggGeneID)
    +0031     keggGeneID = 'kegg';
    +0032 end
    +0033 
    +0034 %% Download gene information
    +0035 webOptions = weboptions('Timeout',30);
    +0036 try
    +0037     gene_list = webread(['http://rest.kegg.jp/list/' keggID],webOptions);
    +0038 catch ME
    +0039     switch ME.identifier
    +0040         case 'MATLAB:webservices:HTTP400StatusCodeError'
    +0041             error(['Unable to download data form KEGG with a potentially invalid ID: ' keggID ])
    +0042         otherwise
    +0043             rethrow(ME)
    +0044     end
    +0045 end
    +0046 gene_list = regexpi(gene_list, '[^\n]+','match')';
    +0047 gene_id   = regexpi(gene_list,['(?<=' keggID ':)\S+'],'match');
    +0048 
    +0049 % Retrieve information for every gene in the list, 10 genes per query
    +0050 genesPerQuery = 10;
    +0051 queries = ceil(numel(gene_id)/genesPerQuery);
    +0052 keggData  = cell(numel(gene_id),1);
    +0053 PB = progressReport(queries, ['Downloading KEGG data for organism code ' keggID]);
    +0054 for i = 1:queries
    +0055     PB.count;
    +0056     % Download batches of genes
    +0057     firstIdx = i*genesPerQuery-(genesPerQuery-1);
    +0058     lastIdx  = i*genesPerQuery;
    +0059     if lastIdx > numel(gene_id) % Last query has probably less genes
    +0060         lastIdx = numel(gene_id);
    +0061     end
    +0062     url      = ['http://rest.kegg.jp/get/' keggID ':' strjoin([gene_id{firstIdx:lastIdx}],['+' keggID ':'])];
    +0063 
    +0064     % KEGG may be temporarily unresponsive, retry with exponential backoff
    +0065     maxRetries = 5;
    +0066     for attempt = 1:maxRetries
    +0067         try
    +0068             out = webread(url,webOptions);
    +0069             break
    +0070         catch ME
    +0071             % A malformed or non-existing query will not succeed on retry
    +0072             noRetry = ismember(ME.identifier,{'MATLAB:webservices:HTTP400StatusCodeError', ...
    +0073                                               'MATLAB:webservices:HTTP404StatusCodeError'});
    +0074             if noRetry || attempt == maxRetries
    +0075                 error(['Unable to download KEGG data (attempt %d of %d).\n' ...
    +0076                        'URL: %s\n' ...
    +0077                        'Check your internet connection and the status of the KEGG ' ...
    +0078                        'REST API, then try again.\nOriginal error: %s'], ...
    +0079                        attempt, maxRetries, url, ME.message);
    +0080             end
    +0081             pause(min(2^attempt,30)) % Wait 2, 4, 8 and 16 seconds before retrying
    +0082         end
    +0083     end
    +0084     outSplit = strsplit(out,['///' 10]); %10 is new line character
    +0085     if numel(outSplit) < lastIdx-firstIdx+2
    +0086         error('KEGG returns less genes per query') %Reduce genesPerQuery
    +0087     end
    +0088     keggData(firstIdx:lastIdx) = outSplit(1:end-1);
    +0089 end
    +0090 
    +0091 %% Parsing of info to keggDB format
    +0092 % Entries returned by KEGG are separated by '///' followed by an empty line,
    +0093 % leaving a stray newline at the start of each entry after splitting. This
    +0094 % would break the startsWith(...,'ENTRY ') checks below, which detect entries
    +0095 % where the regular expression did not match and returned the entry unchanged
    +0096 keggData  = strtrim(keggData);
    +0097 
    +0098 sequence  = regexprep(keggData,'.*AASEQ\s+\d+\s+([A-Z\s])+?\s+NTSEQ.*','$1');
    +0099 %No AASEQ -> no protein -> not of interest
    +0100 noProt    = startsWith(sequence,'ENTRY ');
    +0101 uni       = regexprep(keggData,'.*UniProt: (\S+?)\s.*','$1');
    +0102 noUni     = startsWith(uni,'ENTRY ');
    +0103 uni(noProt | noUni)       = [];
    +0104 keggData(noProt | noUni) = [];
    +0105 sequence(noProt | noUni)  = [];
    +0106 sequence  = regexprep(sequence,'\s+','');
    +0107 keggGene  = regexprep(keggData,'ENTRY\s+(\S+?)\s.+','$1');
    +0108 
    +0109 switch keggGeneID
    +0110     case {'kegg',''}
    +0111         gene_name = keggGene;
    +0112     otherwise
    +0113         % In case there are special characters:
    +0114         keggGeneIDT = regexptranslate('escape',keggGeneID);
    +0115         gene_name = regexprep(keggData,['.+' keggGeneIDT ': (\S+?)\n.+'],'$1');
    +0116         noID = ~contains(keggData,keggGeneIDT);
    +0117         if all(noID)
    +0118             error(['None of the KEGG entries are annotated with the gene identifier ' keggGeneID])
    +0119         else
    +0120             gene_name(noID)= [];
    +0121             keggData(noID) = [];
    +0122             keggGene(noID) = [];
    +0123             sequence(noID) = [];
    +0124             uni(noID)      = [];
    +0125         end
    +0126 end
    +0127 
    +0128 EC_names  = regexprep(keggData,'.*ORTHOLOGY.*\[EC:(.*?)\].*','$1');
    +0129 EC_names(startsWith(EC_names,'ENTRY ')) = {''};
    +0130 
    +0131 MW = cell(numel(sequence),1);
    +0132 for i=1:numel(sequence)
    +0133     if ~isempty(sequence{i})
    +0134         MW{i} = num2str(round(calculateMW(sequence{i})));
    +0135     end
    +0136 end
    +0137 
    +0138 pathway   = regexprep(keggData,'.*PATHWAY\s+(.*?)(BRITE|MODULE).*','$1');
    +0139 pathway(startsWith(pathway,'ENTRY ')) = {''};
    +0140 pathway   = strrep(pathway,[keggID '01100  Metabolic pathways'],'');
    +0141 pathway   = regexprep(pathway,'\n','');
    +0142 pathway   = regexprep(pathway,'           ','');
    +0143 
    +0144 out = [uni, gene_name, keggGene, EC_names, MW, pathway, sequence];
    +0145 out = cell2table(out);
    +0146 
    +0147 writetable(out, filePath, 'FileType', 'text', 'WriteVariableNames',false);
    +0148 fprintf('Model-specific KEGG database stored at %s\n',filePath);
    +0149 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/download_databases/downloadUniProt.html b/doc/src/download_databases/downloadUniProt.html new file mode 100644 index 00000000..8156ae35 --- /dev/null +++ b/doc/src/download_databases/downloadUniProt.html @@ -0,0 +1,146 @@ + + + + Description of downloadUniProt + + + + + + + + + +
    Home > src > download_databases > downloadUniProt.m
    + + + +

    downloadUniProt +

    + +

    PURPOSE ^

    +
    downloadUniProt Download UniProt protein data for an organism and write a TSV.
    + +

    SYNOPSIS ^

    +
    function downloadUniProt(uniprotID, filePath, geneIDfield, type, reviewed)
    + +

    DESCRIPTION ^

    +
     downloadUniProt  Download UniProt protein data for an organism and write a TSV.
    +
    + Downloads accession, gene name, EC number, mass and sequence for every
    + protein matching the given organism identifier, and writes the result
    + to a TSV file. Used by loadDatabases when its expected uniprot.tsv is
    + missing; can also be called directly to refresh one organism's UniProt
    + snapshot without re-running loadDatabases for everything else.
    +
    + Parameters
    + ----------
    + uniprotID : char
    +     UniProt-side identifier whose meaning depends on type, e.g. an NCBI
    +     taxonomy ID such as 559292 for Saccharomyces cerevisiae S288C.
    + filePath : char
    +     destination TSV path (overwritten if it exists).
    + geneIDfield : char
    +     UniProt field that becomes the second column (the gene matching
    +     key) (optional, default 'gene_oln', Ordered Locus Names, which
    +     works for most prokaryotes and budding yeast).
    + type : char
    +     UniProt query field for uniprotID (optional, default
    +     'taxonomy_id'). 'taxonomy' is accepted as an alias.
    + reviewed : logical
    +     whether to restrict the query to reviewed (Swiss-Prot) entries
    +     (optional, default true).
    +
    + Examples
    + --------
    +     downloadUniProt(559292, 'uniprot.tsv');
    +     downloadUniProt(559292, 'uniprot.tsv', 'gene_oln', 'taxonomy_id', true);
    +
    + See also
    + --------
    + loadDatabases, downloadKEGG
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • loadDatabases loadDatabases Load the organism-specific KEGG and UniProt databases.
    + + + + +

    SOURCE CODE ^

    +
    0001 function downloadUniProt(uniprotID, filePath, geneIDfield, type, reviewed)
    +0002 % downloadUniProt  Download UniProt protein data for an organism and write a TSV.
    +0003 %
    +0004 % Downloads accession, gene name, EC number, mass and sequence for every
    +0005 % protein matching the given organism identifier, and writes the result
    +0006 % to a TSV file. Used by loadDatabases when its expected uniprot.tsv is
    +0007 % missing; can also be called directly to refresh one organism's UniProt
    +0008 % snapshot without re-running loadDatabases for everything else.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % uniprotID : char
    +0013 %     UniProt-side identifier whose meaning depends on type, e.g. an NCBI
    +0014 %     taxonomy ID such as 559292 for Saccharomyces cerevisiae S288C.
    +0015 % filePath : char
    +0016 %     destination TSV path (overwritten if it exists).
    +0017 % geneIDfield : char
    +0018 %     UniProt field that becomes the second column (the gene matching
    +0019 %     key) (optional, default 'gene_oln', Ordered Locus Names, which
    +0020 %     works for most prokaryotes and budding yeast).
    +0021 % type : char
    +0022 %     UniProt query field for uniprotID (optional, default
    +0023 %     'taxonomy_id'). 'taxonomy' is accepted as an alias.
    +0024 % reviewed : logical
    +0025 %     whether to restrict the query to reviewed (Swiss-Prot) entries
    +0026 %     (optional, default true).
    +0027 %
    +0028 % Examples
    +0029 % --------
    +0030 %     downloadUniProt(559292, 'uniprot.tsv');
    +0031 %     downloadUniProt(559292, 'uniprot.tsv', 'gene_oln', 'taxonomy_id', true);
    +0032 %
    +0033 % See also
    +0034 % --------
    +0035 % loadDatabases, downloadKEGG
    +0036 
    +0037 if nargin < 3 || isempty(geneIDfield)
    +0038     geneIDfield = 'gene_oln';
    +0039 end
    +0040 if nargin < 4 || isempty(type)
    +0041     type = 'taxonomy_id';
    +0042 end
    +0043 if nargin < 5 || isempty(reviewed)
    +0044     reviewed = true;
    +0045 end
    +0046 if strcmp(type,'taxonomy')
    +0047     type = 'taxonomy_id';
    +0048 end
    +0049 if reviewed
    +0050     uniprotRev = 'reviewed:true+AND+';
    +0051 else
    +0052     uniprotRev = '';
    +0053 end
    +0054 
    +0055 disp(['Downloading Uniprot data for ' type ' ' num2str(uniprotID) '. This can take a few minutes.'])
    +0056 url = ['https://rest.uniprot.org/uniprotkb/stream?query=' uniprotRev ...
    +0057        type ':' num2str(uniprotID) '&fields=accession%2C' geneIDfield ...
    +0058     '%2Cec%2Cmass%2Csequence&format=tsv&compressed=false&sort=protein_name%20asc'];
    +0059 try
    +0060     urlwrite(url,filePath,'Timeout',30);
    +0061     fprintf('Model-specific UniProt database stored at %s\n',filePath);
    +0062 catch
    +0063     error(['Download failed, check your internet connection and try again, or manually download: ' url ...
    +0064         ' After downloading, store the file as ' filePath])
    +0065 end
    +0066 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/download_databases/fetchBrendaAsset.html b/doc/src/download_databases/fetchBrendaAsset.html new file mode 100644 index 00000000..82e2ff1b --- /dev/null +++ b/doc/src/download_databases/fetchBrendaAsset.html @@ -0,0 +1,138 @@ + + + + Description of fetchBrendaAsset + + + + + + + + + +
    Home > src > download_databases > fetchBrendaAsset.m
    + + + +

    fetchBrendaAsset +

    + +

    PURPOSE ^

    +
    fetchBrendaAsset Download (once) GECKO's BRENDA files and return their folder.
    + +

    SYNOPSIS ^

    +
    function folder = fetchBrendaAsset(files)
    + +

    DESCRIPTION ^

    +
     fetchBrendaAsset  Download (once) GECKO's BRENDA files and return their folder.
    +
    + GECKO does not ship BRENDA data. The files of the toolbox-assets release
    + brenda-2026.1-1 (BRENDA 2026.1, CC BY 4.0) are downloaded on first use
    + with RAVEN's fetchToolboxAsset, which checks them against the checksums
    + of the toolbox-assets manifest, and are unpacked into
    + databases/brenda-2026.1-1 in the GECKO folder. geckopy reads the same
    + release (fetch_brenda_asset). A project can use its own BRENDA files
    + instead, in data/brenda (see ModelAdapter.getBrendaDBFolder).
    +
    + Parameters
    + ----------
    + files : cell
    +     file names (default: kcat.tsv, sa.tsv, mw.tsv and measurements.tsv);
    +     the release also has sequences.fasta, substrates.tsv and
    +     kcatCombineParams.tsv.
    +
    + Returns
    + -------
    + folder : char
    +     the folder with the files, unpacked.
    +
    + Examples
    + --------
    +     folder = fetchBrendaAsset();
    +     folder = fetchBrendaAsset({'kcatCombineParams.tsv'});
    +
    + See also
    + --------
    + loadBRENDAdata, loadBrendaMeasurements, ModelAdapter
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function folder = fetchBrendaAsset(files)
    +0002 % fetchBrendaAsset  Download (once) GECKO's BRENDA files and return their folder.
    +0003 %
    +0004 % GECKO does not ship BRENDA data. The files of the toolbox-assets release
    +0005 % brenda-2026.1-1 (BRENDA 2026.1, CC BY 4.0) are downloaded on first use
    +0006 % with RAVEN's fetchToolboxAsset, which checks them against the checksums
    +0007 % of the toolbox-assets manifest, and are unpacked into
    +0008 % databases/brenda-2026.1-1 in the GECKO folder. geckopy reads the same
    +0009 % release (fetch_brenda_asset). A project can use its own BRENDA files
    +0010 % instead, in data/brenda (see ModelAdapter.getBrendaDBFolder).
    +0011 %
    +0012 % Parameters
    +0013 % ----------
    +0014 % files : cell
    +0015 %     file names (default: kcat.tsv, sa.tsv, mw.tsv and measurements.tsv);
    +0016 %     the release also has sequences.fasta, substrates.tsv and
    +0017 %     kcatCombineParams.tsv.
    +0018 %
    +0019 % Returns
    +0020 % -------
    +0021 % folder : char
    +0022 %     the folder with the files, unpacked.
    +0023 %
    +0024 % Examples
    +0025 % --------
    +0026 %     folder = fetchBrendaAsset();
    +0027 %     folder = fetchBrendaAsset({'kcatCombineParams.tsv'});
    +0028 %
    +0029 % See also
    +0030 % --------
    +0031 % loadBRENDAdata, loadBrendaMeasurements, ModelAdapter
    +0032 
    +0033 release = 'brenda-2026.1-1';
    +0034 if nargin < 1 || isempty(files)
    +0035     files = {'kcat.tsv', 'sa.tsv', 'mw.tsv', 'measurements.tsv'};
    +0036 end
    +0037 files = cellstr(files);
    +0038 packed = struct('kcat_tsv', 1, 'sa_tsv', 1, 'mw_tsv', 1, 'measurements_tsv', 1, ...
    +0039     'sequences_fasta', 1, 'substrates_tsv', 1, 'kcatCombineParams_tsv', 0);
    +0040 folder = fullfile(findGECKOroot(), 'databases', release);
    +0041 if exist('fetchToolboxAsset', 'file') ~= 2
    +0042     error('fetchBrendaAsset:raven', ['GECKO downloads its BRENDA files with RAVEN''s ' ...
    +0043         'fetchToolboxAsset, which this RAVEN does not have. Update RAVEN to version 3.'])
    +0044 end
    +0045 for i = 1:numel(files)
    +0046     name = files{i};
    +0047     key = matlab.lang.makeValidName(name);
    +0048     if ~isfield(packed, key)
    +0049         error('fetchBrendaAsset:file', '%s is not a file of %s.', name, release)
    +0050     end
    +0051     target = fullfile(folder, name);
    +0052     if isfile(target)
    +0053         continue
    +0054     end
    +0055     if packed.(key)
    +0056         gz = fetchToolboxAsset(folder, release, [name '.gz']);
    +0057         gunzip(gz, folder);
    +0058     else
    +0059         fetchToolboxAsset(folder, release, name);
    +0060     end
    +0061 end
    +0062 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/download_databases/index.html b/doc/src/download_databases/index.html new file mode 100644 index 00000000..59e9b01c --- /dev/null +++ b/doc/src/download_databases/index.html @@ -0,0 +1,29 @@ + + + + Index for Directory src/download_databases + + + + + + + + + + +
    < Master indexIndex for src/download_databases >
    + +

    Index for src/download_databases

    + +

    Matlab files in this directory:

    + +
     downloadKEGGdownloadKEGG Download a KEGG organism's gene data and write a CSV.
     downloadUniProtdownloadUniProt Download UniProt protein data for an organism and write a TSV.
     fetchBrendaAssetfetchBrendaAsset Download (once) GECKO's BRENDA files and return their folder.
     loadBRENDAdata%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
     loadDatabasesloadDatabases Load the organism-specific KEGG and UniProt databases.
     resolveKcatAggregation%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    + + + + +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/download_databases/loadBRENDAdata.html b/doc/src/download_databases/loadBRENDAdata.html new file mode 100644 index 00000000..1b37fea5 --- /dev/null +++ b/doc/src/download_databases/loadBRENDAdata.html @@ -0,0 +1,311 @@ + + + + Description of loadBRENDAdata + + + + + + + + + +
    Home > src > download_databases > loadBRENDAdata.m
    + + + +

    loadBRENDAdata +

    + +

    PURPOSE ^

    +
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    + +

    SYNOPSIS ^

    +
    function [KCATcell, SAcell] = loadBRENDAdata(varargin)
    + +

    DESCRIPTION ^

    +
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    + loadBRENDAdata  Load kcat and specific activity data from BRENDA files.
    +
    + Reads the BRENDA data files (kcat.tsv, sa.tsv and mw.tsv) from the BRENDA
    + database folder defined by the model adapter, and returns the kcat values
    + and specific activities (the latter converted to kcat values using the
    + molecular weights).
    +
    + kcat.tsv and sa.tsv each carry both a max and a median aggregate per
    + (EC, substrate, organism) triple; kcatAggregation selects which of the
    + two is read. Each file starts with a `#`-prefixed release-version line
    + followed by a tab-delimited column header, both skipped on read.
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + kcatAggregation : char
    +     which aggregate to read from kcat.tsv and sa.tsv, 'max' or
    +     'median' (default: params.kcatAggregation from the model adapter,
    +     or 'max' if the adapter does not set it). A triple's max is the
    +     highest turnover reported for it; its median is the middle one.
    + filterOutlierKcats : logical
    +     whether to drop a row whose kcat is implausibly low for its EC
    +     (default: true). A row is dropped when its kcat is more than four
    +     orders of magnitude below the median kcat of its EC. The reference
    +     median of an EC is taken over the positive kcat values of the max and
    +     median views of kcat.tsv and of the kcat values derived from sa.tsv
    +     and mw.tsv, before any row is dropped, so it does not depend on
    +     kcatAggregation. Wildcard ECs (containing '-') do not contribute to a
    +     reference. The EC level widens from w.x.y.z to w.x.y, w.x and w while
    +     fewer than five values are available. Set to false to keep every row.
    +
    + Returns
    + -------
    + KCATcell : cell
    +     kcat data extracted from BRENDA.
    + SAcell : cell
    +     specific activity data extracted from BRENDA.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     [KCATcell, SAcell] = loadBRENDAdata();
    +     [KCATcell, SAcell] = loadBRENDAdata('modelAdapter', adapter);
    +     [KCATcell, SAcell] = loadBRENDAdata('kcatAggregation', 'median');
    +     [KCATcell, SAcell] = loadBRENDAdata('filterOutlierKcats', false);
    +
    + See also
    + --------
    + loadDatabases, getECfromDatabase
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: + +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0002 function [KCATcell, SAcell] = loadBRENDAdata(varargin)
    +0003 % loadBRENDAdata  Load kcat and specific activity data from BRENDA files.
    +0004 %
    +0005 % Reads the BRENDA data files (kcat.tsv, sa.tsv and mw.tsv) from the BRENDA
    +0006 % database folder defined by the model adapter, and returns the kcat values
    +0007 % and specific activities (the latter converted to kcat values using the
    +0008 % molecular weights).
    +0009 %
    +0010 % kcat.tsv and sa.tsv each carry both a max and a median aggregate per
    +0011 % (EC, substrate, organism) triple; kcatAggregation selects which of the
    +0012 % two is read. Each file starts with a `#`-prefixed release-version line
    +0013 % followed by a tab-delimited column header, both skipped on read.
    +0014 %
    +0015 % Name-Value Arguments
    +0016 % --------------------
    +0017 % modelAdapter : ModelAdapter
    +0018 %     a loaded model adapter (default: the current default model adapter).
    +0019 % kcatAggregation : char
    +0020 %     which aggregate to read from kcat.tsv and sa.tsv, 'max' or
    +0021 %     'median' (default: params.kcatAggregation from the model adapter,
    +0022 %     or 'max' if the adapter does not set it). A triple's max is the
    +0023 %     highest turnover reported for it; its median is the middle one.
    +0024 % filterOutlierKcats : logical
    +0025 %     whether to drop a row whose kcat is implausibly low for its EC
    +0026 %     (default: true). A row is dropped when its kcat is more than four
    +0027 %     orders of magnitude below the median kcat of its EC. The reference
    +0028 %     median of an EC is taken over the positive kcat values of the max and
    +0029 %     median views of kcat.tsv and of the kcat values derived from sa.tsv
    +0030 %     and mw.tsv, before any row is dropped, so it does not depend on
    +0031 %     kcatAggregation. Wildcard ECs (containing '-') do not contribute to a
    +0032 %     reference. The EC level widens from w.x.y.z to w.x.y, w.x and w while
    +0033 %     fewer than five values are available. Set to false to keep every row.
    +0034 %
    +0035 % Returns
    +0036 % -------
    +0037 % KCATcell : cell
    +0038 %     kcat data extracted from BRENDA.
    +0039 % SAcell : cell
    +0040 %     specific activity data extracted from BRENDA.
    +0041 %
    +0042 % Examples
    +0043 % --------
    +0044 %     % optional arguments may be given positionally or as name-value pairs:
    +0045 %     [KCATcell, SAcell] = loadBRENDAdata();
    +0046 %     [KCATcell, SAcell] = loadBRENDAdata('modelAdapter', adapter);
    +0047 %     [KCATcell, SAcell] = loadBRENDAdata('kcatAggregation', 'median');
    +0048 %     [KCATcell, SAcell] = loadBRENDAdata('filterOutlierKcats', false);
    +0049 %
    +0050 % See also
    +0051 % --------
    +0052 % loadDatabases, getECfromDatabase
    +0053 
    +0054 p = parseGECKOargs(varargin, { ...
    +0055     'modelAdapter',    [], @(x) assert(isempty(x) || isa(x,'ModelAdapter'), ...
    +0056                                 'loadBRENDAdata:invalidModelAdapter', ...
    +0057                                 'modelAdapter must be a ModelAdapter.'); ...
    +0058     'kcatAggregation', [], @(x) assert(isempty(x) || any(strcmpi(x, ...
    +0059                                 {'max','median'})), ...
    +0060                                 'loadBRENDAdata:invalidKcatAggregation', ...
    +0061                                 'kcatAggregation must be ''max'' or ''median''.'); ...
    +0062     'filterOutlierKcats', true, @(x) assert((islogical(x) || isnumeric(x)) && ...
    +0063                                 isscalar(x), ...
    +0064                                 'loadBRENDAdata:invalidFilterOutlierKcats', ...
    +0065                                 'filterOutlierKcats must be a logical scalar.')});
    +0066 modelAdapter       = p.modelAdapter;
    +0067 kcatAggregation    = p.kcatAggregation;
    +0068 filterOutlierKcats = logical(p.filterOutlierKcats);
    +0069 
    +0070 if isempty(modelAdapter)
    +0071     modelAdapter = ModelAdapterManager.getDefault();
    +0072     if isempty(modelAdapter)
    +0073         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0074     end
    +0075 end
    +0076 
    +0077 kcatAggregation = resolveKcatAggregation(kcatAggregation, modelAdapter);
    +0078 %Column 4 holds the per-triple maximum and column 5 the median; both are
    +0079 %read, so that the outlier filter can use the max and the median views.
    +0080 valueCol = 4 + strcmpi(kcatAggregation,'median');
    +0081 
    +0082 basePath      = modelAdapter.getBrendaDBFolder();
    +0083 KCAT_file      = fullfile(basePath,'kcat.tsv');
    +0084 SA_file        = fullfile(basePath,'sa.tsv');
    +0085 MW_file        = fullfile(basePath,'mw.tsv');
    +0086 
    +0087 %Extract BRENDA DATA from files information. kcat.tsv/sa.tsv are seven
    +0088 %columns (ec_code, substrate, organism, value_max, value_median, n,
    +0089 %references); the data cells hold ec_code, substrate, organism, the max and
    +0090 %the median. mw.tsv is six columns (no substrate-level aggregation choice):
    +0091 %ec_code, substrate, organism, value, n, references.
    +0092 KCAT          = openDataFile(KCAT_file,1,'%q %q %q %f %f %f %q',[4 5]);
    +0093 scalingFactor = 1/60;    %[umol/min/mg] -> [mmol/s/g]
    +0094 SA            = openDataFile(SA_file,scalingFactor,'%q %q %q %f %f %f %q',[4 5]);
    +0095 scalingFactor = 1/1000;  %[g/mol] -> [g/mmol]
    +0096 MW            = openDataFile(MW_file,scalingFactor,'%q %q %q %f %f %q',4);
    +0097 
    +0098 %build an index on MW{1} to speed things up a bit
    +0099 %first just extract the genus (i.e. the first part of the name)
    +0100 MWECNum = unique(upper(MW{1}));
    +0101 MWECNumIndices = cell(length(MWECNum),1);
    +0102 MWECNumHashMap = containers.Map(MWECNum,1:length(MWECNum));
    +0103 for i = 1:length(MW{1})
    +0104     matchInd = cell2mat(values(MWECNumHashMap, upper(MW{1}(i))));
    +0105     MWECNumIndices{matchInd} = [MWECNumIndices{matchInd};i];
    +0106 end
    +0107 
    +0108 %Match each specific activity to the molecular weight of its EC and
    +0109 %organism. The first match is used.
    +0110 previousEC = []; EC_indexes = [];
    +0111 saRows = zeros(length(SA{1}),1);
    +0112 mwVals = zeros(length(SA{1}),1);
    +0113 nMatched = 0;
    +0114 for i=1:length(SA{1})
    +0115     %Gets the indexes of the EC repetitions in the MW cell for every
    +0116     %new (different) EC
    +0117     if ~strcmpi(SA{1}(i), previousEC)
    +0118         key = upper(SA{1}(i));
    +0119         if isKey(MWECNumHashMap,key) %annoyingly, this seems to be needed
    +0120             matchInd = cell2mat(values(MWECNumHashMap,key));
    +0121             EC_indexes = MWECNumIndices{matchInd};
    +0122         else
    +0123             EC_indexes = [];
    +0124         end
    +0125     end
    +0126     mwEC{1} = MW{3}(EC_indexes); mwEC{2} = MW{4}(EC_indexes);
    +0127     % just looks for the first match because just the maximal value for
    +0128     % each EC# / Orgaism is reported on the file
    +0129     org_index = find(strcmpi(SA{3}(i),mwEC{1}),1);
    +0130     if ~isempty(org_index)
    +0131         nMatched = nMatched + 1;
    +0132         saRows(nMatched) = i;
    +0133         mwVals(nMatched) = mwEC{2}(org_index);
    +0134     end
    +0135     previousEC = SA{1}(i);
    +0136 end
    +0137 saRows = saRows(1:nMatched);
    +0138 mwVals = mwVals(1:nMatched);
    +0139 
    +0140 %Specific activities as kcat values [1/s], for the max and the median
    +0141 saEC     = SA{1}(saRows);
    +0142 saMax    = SA{4}(saRows).*mwVals;
    +0143 saMedian = SA{5}(saRows).*mwVals;
    +0144 
    +0145 if valueCol == 4
    +0146     saSelected = saMax;
    +0147 else
    +0148     saSelected = saMedian;
    +0149 end
    +0150 
    +0151 %Drop kcats that are implausibly low for their EC
    +0152 keepKcat = true(size(KCAT{1}));
    +0153 keepSA   = true(size(saEC));
    +0154 if filterOutlierKcats
    +0155     ecPool  = [KCAT{1}; KCAT{1}; saEC; saEC];
    +0156     valPool = [KCAT{4}; KCAT{5}; saMax; saMedian];
    +0157     keepKcat = ~isOutlier(KCAT{1},KCAT{valueCol},ecPool,valPool);
    +0158     keepSA   = ~isOutlier(saEC,saSelected,ecPool,valPool);
    +0159 end
    +0160 
    +0161 KCATcell = {KCAT{1}(keepKcat), KCAT{2}(keepKcat), KCAT{3}(keepKcat), ...
    +0162             KCAT{valueCol}(keepKcat)};
    +0163 if nMatched > 0
    +0164     SAcell = {saEC(keepSA), SA{3}(saRows(keepSA)), saSelected(keepSA), ...
    +0165               mwVals(keepSA)};
    +0166 else
    +0167     SAcell = {[],[],[],[]};
    +0168 end
    +0169 end
    +0170 
    +0171 function data_cell = openDataFile(fileName,scalingFactor,formatSpec,valueCols)
    +0172 fID          = fopen(fileName);
    +0173 raw          = textscan(fID,formatSpec,'delimiter','\t','HeaderLines',2);
    +0174 fclose(fID);
    +0175 data_cell    = [raw(1:3), cellfun(@(c) raw{c}*scalingFactor, num2cell(valueCols), ...
    +0176                                   'UniformOutput', false)];
    +0177 end
    +0178 
    +0179 function outlier = isOutlier(ecs,vals,ecPool,valPool)
    +0180 %A value is an outlier if it is more than 'decades' orders of magnitude below
    +0181 %the median kcat of its own EC, taken over the pool of values. The EC widens
    +0182 %from the full code to its 3-, 2- and 1-level prefix while fewer than minRef
    +0183 %values are available.
    +0184 decades = 4;
    +0185 minRef  = 5;
    +0186 usePool = valPool > 0 & ~contains(ecPool,'-');
    +0187 ecPool  = ecPool(usePool);
    +0188 logPool = log10(valPool(usePool));
    +0189 refLog  = NaN(size(ecs));
    +0190 if isempty(ecs) || isempty(logPool)
    +0191     outlier = false(size(ecs));
    +0192     return
    +0193 end
    +0194 for level = 4:-1:1
    +0195     poolKey = ecPrefix(ecPool,level);
    +0196     [grp,keys] = findgroups(poolKey);
    +0197     nPerKey    = accumarray(grp,1);
    +0198     medPerKey  = splitapply(@median,logPool,grp);
    +0199     [found,loc] = ismember(ecPrefix(ecs,level),keys);
    +0200     use = isnan(refLog) & found;
    +0201     use(use) = nPerKey(loc(use)) >= minRef;
    +0202     refLog(use) = medPerKey(loc(use));
    +0203 end
    +0204 outlier = vals > 0 & ~isnan(refLog) & log10(vals) < refLog - decades;
    +0205 end
    +0206 
    +0207 function prefix = ecPrefix(ecs,level)
    +0208 %The first 'level' dot-separated parts of each EC code
    +0209 prefix = regexp(ecs,['^[^.]*(?:\.[^.]*){0,' num2str(level-1) '}'],'match','once');
    +0210 prefix(cellfun(@isempty,prefix)) = {''};
    +0211 prefix = reshape(prefix,size(ecs));
    +0212 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/download_databases/loadDatabases.html b/doc/src/download_databases/loadDatabases.html new file mode 100644 index 00000000..b736ff63 --- /dev/null +++ b/doc/src/download_databases/loadDatabases.html @@ -0,0 +1,192 @@ + + + + Description of loadDatabases + + + + + + + + + +
    Home > src > download_databases > loadDatabases.m
    + + + +

    loadDatabases +

    + +

    PURPOSE ^

    +
    loadDatabases Load the organism-specific KEGG and UniProt databases.
    + +

    SYNOPSIS ^

    +
    function databases = loadDatabases(varargin)
    + +

    DESCRIPTION ^

    +
     loadDatabases  Load the organism-specific KEGG and UniProt databases.
    +
    + Loads (and downloads if necessary) the organism-specific KEGG and UniProt
    + databases that are required to extract protein information. The uniprot.ID
    + and kegg.ID are taken from the ModelAdapter.
    +
    + Name-Value Arguments
    + --------------------
    + selectDatabase : char
    +     which databases should be loaded, either 'uniprot', 'kegg' or 'both'
    +     (default 'both').
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter;
    +     send in [] for default).
    +
    + Returns
    + -------
    + databases : struct
    +     contains .uniprot and .kegg structures, dependent on which databases
    +     were selected.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     databases = loadDatabases('both', adapter);
    +     databases = loadDatabases('selectDatabase', 'both');
    +
    + See also
    + --------
    + getECfromDatabase, loadBRENDAdata, downloadKEGG, downloadUniProt
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • downloadKEGG downloadKEGG Download a KEGG organism's gene data and write a CSV.
    • downloadUniProt downloadUniProt Download UniProt protein data for an organism and write a TSV.
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function databases = loadDatabases(varargin)
    +0002 % loadDatabases  Load the organism-specific KEGG and UniProt databases.
    +0003 %
    +0004 % Loads (and downloads if necessary) the organism-specific KEGG and UniProt
    +0005 % databases that are required to extract protein information. The uniprot.ID
    +0006 % and kegg.ID are taken from the ModelAdapter.
    +0007 %
    +0008 % Name-Value Arguments
    +0009 % --------------------
    +0010 % selectDatabase : char
    +0011 %     which databases should be loaded, either 'uniprot', 'kegg' or 'both'
    +0012 %     (default 'both').
    +0013 % modelAdapter : ModelAdapter
    +0014 %     a loaded model adapter (default: the current default model adapter;
    +0015 %     send in [] for default).
    +0016 %
    +0017 % Returns
    +0018 % -------
    +0019 % databases : struct
    +0020 %     contains .uniprot and .kegg structures, dependent on which databases
    +0021 %     were selected.
    +0022 %
    +0023 % Examples
    +0024 % --------
    +0025 %     % optional arguments may be given positionally or as name-value pairs:
    +0026 %     databases = loadDatabases('both', adapter);
    +0027 %     databases = loadDatabases('selectDatabase', 'both');
    +0028 %
    +0029 % See also
    +0030 % --------
    +0031 % getECfromDatabase, loadBRENDAdata, downloadKEGG, downloadUniProt
    +0032 
    +0033 p = parseGECKOargs(varargin, { ...
    +0034     'selectDatabase', 'both'; ...
    +0035     'modelAdapter',   []});
    +0036 selectDatabase = p.selectDatabase;
    +0037 modelAdapter   = p.modelAdapter;
    +0038 
    +0039 if isempty(modelAdapter)
    +0040     modelAdapter = ModelAdapterManager.getDefault();
    +0041     if isempty(modelAdapter)
    +0042         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0043     end
    +0044 end
    +0045 
    +0046 params      = modelAdapter.getParameters();
    +0047 kegg.ID      = params.kegg.ID;
    +0048 uniprot.ID   = params.uniprot.ID;
    +0049 filePath    = fullfile(params.path,'data');
    +0050 uniprot.geneIDfield = params.uniprot.geneIDfield;
    +0051 uniprot.type = params.uniprot.type;
    +0052 kegg.geneID = params.kegg.geneID;
    +0053 
    +0054 warning('off', 'MATLAB:MKDIR:DirectoryExists');
    +0055 
    +0056 databases.uniprot = [];
    +0057 databases.kegg = [];
    +0058 
    +0059 %% Uniprot
    +0060 if any(strcmp(selectDatabase,{'uniprot','both'}))
    +0061     uniprotPath = fullfile(filePath,'uniprot.tsv');
    +0062     if ~exist(uniprotPath,'file')
    +0063         if isempty(uniprot.ID)
    +0064             printOrange('WARNING: No uniprot.ID is specified, unable to download UniProt DB.\n');
    +0065         end
    +0066         downloadUniProt(uniprot.ID, uniprotPath, uniprot.geneIDfield, uniprot.type, params.uniprot.reviewed);
    +0067     end
    +0068     if exist(uniprotPath,'file')
    +0069         fid         = fopen(uniprotPath,'r');
    +0070         fileContent = textscan(fid,'%q %q %q %q %q','Delimiter','\t','HeaderLines',1);
    +0071         fclose(fid);
    +0072         databases.uniprot.ID      = fileContent{1};
    +0073         databases.uniprot.genes   = fileContent{2};
    +0074         databases.uniprot.eccodes = fileContent{3};
    +0075         databases.uniprot.MW      = str2double(fileContent{4});
    +0076         databases.uniprot.seq     = fileContent{5};
    +0077     else
    +0078         databases.uniprot = [];
    +0079     end
    +0080     if ~isempty(databases.uniprot)
    +0081         [uniqueIDs,uniqueIdx] = unique(databases.uniprot.ID,'stable');
    +0082         if numel(uniqueIDs) < numel(databases.uniprot.ID)
    +0083             duplID = setdiff(1:numel(databases.uniprot.ID),uniqueIdx);
    +0084             error('%s', ravenList(['Duplicate entries are found for the following proteins. '...
    +0085                     'Manually curate the ''uniprot.tsv'' file, or adjust the uniprot parameters '...
    +0086                     'in the model adapter:'],databases.uniprot.ID(duplID)));
    +0087         end
    +0088     end
    +0089 end
    +0090 
    +0091 %% KEGG
    +0092 if any(strcmp(selectDatabase,{'kegg','both'}))
    +0093     keggPath = fullfile(filePath,'kegg.tsv');
    +0094     if ~exist(keggPath,'file')
    +0095         if isempty(kegg.ID)
    +0096             printOrange('WARNING: No kegg.ID is specified, unable to download KEGG DB.\n');
    +0097         else
    +0098             downloadKEGG(kegg.ID,keggPath,kegg.geneID);
    +0099         end
    +0100     end
    +0101     if exist(keggPath,'file')
    +0102         fid         = fopen(keggPath,'r');
    +0103         fileContent = textscan(fid,'%q %q %q %q %q %q %q','Delimiter',',','HeaderLines',0);
    +0104         fclose(fid);
    +0105         databases.kegg.uniprot    = fileContent{1};
    +0106         databases.kegg.genes      = fileContent{2};
    +0107         databases.kegg.keggGene   = fileContent{3};
    +0108         databases.kegg.eccodes    = fileContent{4};
    +0109         databases.kegg.MW         = str2double(fileContent{5});
    +0110         databases.kegg.pathway    = fileContent{6};
    +0111         databases.kegg.seq        = fileContent{7};
    +0112     else
    +0113         databases.kegg = [];
    +0114     end
    +0115 end
    +0116 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/download_databases/resolveKcatAggregation.html b/doc/src/download_databases/resolveKcatAggregation.html new file mode 100644 index 00000000..034c9fd3 --- /dev/null +++ b/doc/src/download_databases/resolveKcatAggregation.html @@ -0,0 +1,112 @@ + + + + Description of resolveKcatAggregation + + + + + + + + + +
    Home > src > download_databases > resolveKcatAggregation.m
    + + + +

    resolveKcatAggregation +

    + +

    PURPOSE ^

    +
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    + +

    SYNOPSIS ^

    +
    function kcatAggregation = resolveKcatAggregation(kcatAggregation, modelAdapter)
    + +

    DESCRIPTION ^

    +
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    + resolveKcatAggregation  Settle which BRENDA aggregate to read.
    +
    + The BRENDA snapshot records both a maximum and a median per
    + (EC, substrate, organism) triple. Which one a run uses can be given per
    + call, or once on the model adapter as params.kcatAggregation; an
    + adapter that sets neither gets 'max', which is what GECKO has always
    + used.
    +
    + Input Arguments
    + ---------------
    + kcatAggregation : char
    +     the per-call choice, or empty to fall back to the adapter.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter.
    +
    + Returns
    + -------
    + kcatAggregation : char
    +     'max' or 'median'.
    +
    + See also
    + --------
    + loadBRENDAdata, fuzzyKcatMatching
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • loadBRENDAdata %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    + + + + +

    SOURCE CODE ^

    +
    0001 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0002 function kcatAggregation = resolveKcatAggregation(kcatAggregation, modelAdapter)
    +0003 % resolveKcatAggregation  Settle which BRENDA aggregate to read.
    +0004 %
    +0005 % The BRENDA snapshot records both a maximum and a median per
    +0006 % (EC, substrate, organism) triple. Which one a run uses can be given per
    +0007 % call, or once on the model adapter as params.kcatAggregation; an
    +0008 % adapter that sets neither gets 'max', which is what GECKO has always
    +0009 % used.
    +0010 %
    +0011 % Input Arguments
    +0012 % ---------------
    +0013 % kcatAggregation : char
    +0014 %     the per-call choice, or empty to fall back to the adapter.
    +0015 % modelAdapter : ModelAdapter
    +0016 %     a loaded model adapter.
    +0017 %
    +0018 % Returns
    +0019 % -------
    +0020 % kcatAggregation : char
    +0021 %     'max' or 'median'.
    +0022 %
    +0023 % See also
    +0024 % --------
    +0025 % loadBRENDAdata, fuzzyKcatMatching
    +0026 
    +0027 if isempty(kcatAggregation)
    +0028     params = modelAdapter.getParameters();
    +0029     if isfield(params,'kcatAggregation') && ~isempty(params.kcatAggregation)
    +0030         kcatAggregation = params.kcatAggregation;
    +0031     else
    +0032         kcatAggregation = 'max';
    +0033     end
    +0034 end
    +0035 
    +0036 if ~(ischar(kcatAggregation) || isstring(kcatAggregation)) || ...
    +0037         ~any(strcmpi(kcatAggregation,{'max','median'}))
    +0038     error('resolveKcatAggregation:invalidKcatAggregation', ...
    +0039         'kcatAggregation must be ''max'' or ''median''.')
    +0040 end
    +0041 kcatAggregation = lower(char(kcatAggregation));
    +0042 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/enzyme_usage/getEnzymeBottlenecks.html b/doc/src/enzyme_usage/getEnzymeBottlenecks.html new file mode 100644 index 00000000..845d1271 --- /dev/null +++ b/doc/src/enzyme_usage/getEnzymeBottlenecks.html @@ -0,0 +1,147 @@ + + + + Description of getEnzymeBottlenecks + + + + + + + + + +
    Home > src > enzyme_usage > getEnzymeBottlenecks.m
    + + + +

    getEnzymeBottlenecks +

    + +

    PURPOSE ^

    +
    getEnzymeBottlenecks Top-N enzymes limiting the current objective.
    + +

    SYNOPSIS ^

    +
    function bottlenecks = getEnzymeBottlenecks(model, varargin)
    + +

    DESCRIPTION ^

    +
     getEnzymeBottlenecks  Top-N enzymes limiting the current objective.
    +
    + Solves the model and ranks every enzyme by the absolute shadow price of
    + its prot_<id> mass-balance constraint --- the enzymes whose extra
    + availability would help the objective the most.
    +
    + Parameters
    + ----------
    + model : struct
    +     a full ecModel in GECKO 3 format (with ecModel.ec structure). Not
    +     supported for gecko-light models, which have no per-enzyme
    +     prot_<id> / usage_prot_<id> machinery.
    +
    + Name-Value Arguments
    + --------------------
    + top : double
    +     number of enzymes to return (default 10).
    +
    + Returns
    + -------
    + bottlenecks : table
    +     one row per returned enzyme, sorted by descending absolute shadow
    +     price, with columns uniprot, gene, shadowPrice, flux, capUsage
    +     (abs(flux)/upperBound, NaN if upperBound is 0) and upperBound.
    +
    + Examples
    + --------
    +     bottlenecks = getEnzymeBottlenecks(ecModel);
    +     bottlenecks = getEnzymeBottlenecks(ecModel, 'top', 5);
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function bottlenecks = getEnzymeBottlenecks(model, varargin)
    +0002 % getEnzymeBottlenecks  Top-N enzymes limiting the current objective.
    +0003 %
    +0004 % Solves the model and ranks every enzyme by the absolute shadow price of
    +0005 % its prot_<id> mass-balance constraint --- the enzymes whose extra
    +0006 % availability would help the objective the most.
    +0007 %
    +0008 % Parameters
    +0009 % ----------
    +0010 % model : struct
    +0011 %     a full ecModel in GECKO 3 format (with ecModel.ec structure). Not
    +0012 %     supported for gecko-light models, which have no per-enzyme
    +0013 %     prot_<id> / usage_prot_<id> machinery.
    +0014 %
    +0015 % Name-Value Arguments
    +0016 % --------------------
    +0017 % top : double
    +0018 %     number of enzymes to return (default 10).
    +0019 %
    +0020 % Returns
    +0021 % -------
    +0022 % bottlenecks : table
    +0023 %     one row per returned enzyme, sorted by descending absolute shadow
    +0024 %     price, with columns uniprot, gene, shadowPrice, flux, capUsage
    +0025 %     (abs(flux)/upperBound, NaN if upperBound is 0) and upperBound.
    +0026 %
    +0027 % Examples
    +0028 % --------
    +0029 %     bottlenecks = getEnzymeBottlenecks(ecModel);
    +0030 %     bottlenecks = getEnzymeBottlenecks(ecModel, 'top', 5);
    +0031 
    +0032 p = parseGECKOargs(varargin, {'top', []});
    +0033 top = p.top;
    +0034 if isempty(top)
    +0035     top = 10;
    +0036 end
    +0037 
    +0038 if isfield(model.ec, 'geckoLight') && model.ec.geckoLight
    +0039     error(['getEnzymeBottlenecks requires a full ecModel, not gecko-light: ' ...
    +0040         'light models have no per-enzyme prot_<id> / usage_prot_<id> machinery.'])
    +0041 end
    +0042 
    +0043 sol = solveLP(model);
    +0044 if sol.stat ~= 1
    +0045     error('getEnzymeBottlenecks: solver status %d; cannot rank bottlenecks.', sol.stat)
    +0046 end
    +0047 
    +0048 uniprot = model.ec.enzymes(:);
    +0049 gene    = model.ec.genes(:);
    +0050 
    +0051 protMets  = strcat('prot_', uniprot);
    +0052 [found, metIdx] = ismember(protMets, model.mets);
    +0053 if ~all(found)
    +0054     error('Cannot find prot_<id> metabolites for all enzymes. This is done by makeEcModel.')
    +0055 end
    +0056 usageRxns = strcat('usage_prot_', uniprot);
    +0057 [found, rxnIdx] = ismember(usageRxns, model.rxns);
    +0058 if ~all(found)
    +0059     error('Usage reactions are not defined for all enzymes. This is done by makeEcModel.')
    +0060 end
    +0061 
    +0062 shadowPrice = sol.sPrice(metIdx);
    +0063 flux        = sol.x(rxnIdx);
    +0064 upperBound  = model.ub(rxnIdx);
    +0065 capUsage    = abs(flux) ./ upperBound;
    +0066 capUsage(upperBound == 0) = NaN;
    +0067 
    +0068 bottlenecks = table(uniprot, gene, shadowPrice, flux, capUsage, upperBound);
    +0069 [~, order] = sort(abs(bottlenecks.shadowPrice), 'descend');
    +0070 bottlenecks = bottlenecks(order, :);
    +0071 bottlenecks = bottlenecks(1:min(top, height(bottlenecks)), :);
    +0072 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/enzyme_usage/getEnzymeUsage.html b/doc/src/enzyme_usage/getEnzymeUsage.html new file mode 100644 index 00000000..1e0af77c --- /dev/null +++ b/doc/src/enzyme_usage/getEnzymeUsage.html @@ -0,0 +1,174 @@ + + + + Description of getEnzymeUsage + + + + + + + + + +
    Home > src > enzyme_usage > getEnzymeUsage.m
    + + + +

    getEnzymeUsage +

    + +

    PURPOSE ^

    +
    getEnzymeUsage Compute enzyme usages from a provided flux distribution.
    + +

    SYNOPSIS ^

    +
    function usageData = getEnzymeUsage(ecModel,fluxes,varargin)
    + +

    DESCRIPTION ^

    +
     getEnzymeUsage  Compute enzyme usages from a provided flux distribution.
    +
    + Gives enzyme usages based on a provided flux distribution, as obtained
    + from a full GECKO model. It can give:
    +
    + 1. absolute usage: the specific enzyme usage in mg/gDCW, which can be
    +    given for enzymes with- and without concentration information;
    + 2. capacity usage: the ratio of available enzyme that is used, calculated
    +    by (absUsage/UB) (note that capacity usage is 0 if an enzyme
    +    concentration was not constrained in the model);
    + 3. UB: the upper bound of each enzyme exchange reaction, which may not be
    +    the same as the enzyme concentration, if it has been flexibilized;
    + 4. protID: the protein identifiers for each enzyme, in the same order as
    +    ecModel.ec.enzymes.
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    + fluxes : double
    +     vector of fluxes, for instance sol.x.
    +
    + Name-Value Arguments
    + --------------------
    + zero : logical
    +     whether also enzymes with zero absolute usage should be included
    +     (default true).
    +
    + Returns
    + -------
    + usageData : struct
    +     structure with enzyme usage data.
    +
    + Notes
    + -----
    + The usageData structure has the following fields:
    +
    + - capUsage : vector of enzyme capacity usages.
    + - absUsage : vector of absolute enzyme usages.
    + - UB : vector of enzyme exchange reaction upper bounds.
    + - protID : string array of matching protein IDs.
    + - fluxes : vector of fluxes, copy of input fluxes.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     usageData = getEnzymeUsage(ecModel,fluxes,zero);
    +     usageData = getEnzymeUsage(ecModel,fluxes,'zero',false);
    +
    + See also
    + --------
    + reportEnzymeUsage
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function usageData = getEnzymeUsage(ecModel,fluxes,varargin)
    +0002 % getEnzymeUsage  Compute enzyme usages from a provided flux distribution.
    +0003 %
    +0004 % Gives enzyme usages based on a provided flux distribution, as obtained
    +0005 % from a full GECKO model. It can give:
    +0006 %
    +0007 % 1. absolute usage: the specific enzyme usage in mg/gDCW, which can be
    +0008 %    given for enzymes with- and without concentration information;
    +0009 % 2. capacity usage: the ratio of available enzyme that is used, calculated
    +0010 %    by (absUsage/UB) (note that capacity usage is 0 if an enzyme
    +0011 %    concentration was not constrained in the model);
    +0012 % 3. UB: the upper bound of each enzyme exchange reaction, which may not be
    +0013 %    the same as the enzyme concentration, if it has been flexibilized;
    +0014 % 4. protID: the protein identifiers for each enzyme, in the same order as
    +0015 %    ecModel.ec.enzymes.
    +0016 %
    +0017 % Parameters
    +0018 % ----------
    +0019 % ecModel : struct
    +0020 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0021 % fluxes : double
    +0022 %     vector of fluxes, for instance sol.x.
    +0023 %
    +0024 % Name-Value Arguments
    +0025 % --------------------
    +0026 % zero : logical
    +0027 %     whether also enzymes with zero absolute usage should be included
    +0028 %     (default true).
    +0029 %
    +0030 % Returns
    +0031 % -------
    +0032 % usageData : struct
    +0033 %     structure with enzyme usage data.
    +0034 %
    +0035 % Notes
    +0036 % -----
    +0037 % The usageData structure has the following fields:
    +0038 %
    +0039 % - capUsage : vector of enzyme capacity usages.
    +0040 % - absUsage : vector of absolute enzyme usages.
    +0041 % - UB : vector of enzyme exchange reaction upper bounds.
    +0042 % - protID : string array of matching protein IDs.
    +0043 % - fluxes : vector of fluxes, copy of input fluxes.
    +0044 %
    +0045 % Examples
    +0046 % --------
    +0047 %     % optional arguments may be given positionally or as name-value pairs:
    +0048 %     usageData = getEnzymeUsage(ecModel,fluxes,zero);
    +0049 %     usageData = getEnzymeUsage(ecModel,fluxes,'zero',false);
    +0050 %
    +0051 % See also
    +0052 % --------
    +0053 % reportEnzymeUsage
    +0054 
    +0055 p = parseGECKOargs(varargin, { ...
    +0056     'zero', true});
    +0057 zero = p.zero;
    +0058 if ecModel.ec.geckoLight
    +0059     error('This function does not work on GECKO light models.')
    +0060 end
    +0061 usageData.protID      = ecModel.ec.enzymes;
    +0062 [~,rxnIdx] = ismember(strcat('usage_prot_',ecModel.ec.enzymes),ecModel.rxns);
    +0063 
    +0064 usageData.UB          = ecModel.ub(rxnIdx);
    +0065 usageData.absUsage    = abs(fluxes(rxnIdx));
    +0066 usageData.capUsage    = abs(usageData.absUsage./usageData.UB);
    +0067 usageData.fluxes      = fluxes;
    +0068 
    +0069 if ~zero
    +0070     nonzero               = usageData.absUsage>0;
    +0071     usageData.absUsage    = usageData.absUsage(nonzero);
    +0072     usageData.capUsage    = usageData.capUsage(nonzero);
    +0073     usageData.UB          = usageData.UB(nonzero);
    +0074     usageData.protID      = usageData.protID(nonzero);
    +0075 end
    +0076 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/enzyme_usage/index.html b/doc/src/enzyme_usage/index.html new file mode 100644 index 00000000..6a4c8eac --- /dev/null +++ b/doc/src/enzyme_usage/index.html @@ -0,0 +1,29 @@ + + + + Index for Directory src/enzyme_usage + + + + + + + + + + +
    < Master indexIndex for src/enzyme_usage >
    + +

    Index for src/enzyme_usage

    + +

    Matlab files in this directory:

    + +
     getEnzymeBottlenecksgetEnzymeBottlenecks Top-N enzymes limiting the current objective.
     getEnzymeUsagegetEnzymeUsage Compute enzyme usages from a provided flux distribution.
     reportEnzymeUsagereportEnzymeUsage Summarize the results from getEnzymeUsage.
    + + + + +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/enzyme_usage/reportEnzymeUsage.html b/doc/src/enzyme_usage/reportEnzymeUsage.html new file mode 100644 index 00000000..ff32b83a --- /dev/null +++ b/doc/src/enzyme_usage/reportEnzymeUsage.html @@ -0,0 +1,285 @@ + + + + Description of reportEnzymeUsage + + + + + + + + + +
    Home > src > enzyme_usage > reportEnzymeUsage.m
    + + + +

    reportEnzymeUsage +

    + +

    PURPOSE ^

    +
    reportEnzymeUsage Summarize the results from getEnzymeUsage.
    + +

    SYNOPSIS ^

    +
    function usageReport = reportEnzymeUsage(ecModel, usageData, varargin)
    + +

    DESCRIPTION ^

    +
     reportEnzymeUsage  Summarize the results from getEnzymeUsage.
    +
    + Ranks the enzymes from getEnzymeUsage into two tables: those with the
    + highest capacity usage, and those with the highest absolute usage.
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     a GECKO3 ecModel.
    + usageData : struct
    +     output from getEnzymeUsage.
    +
    + Name-Value Arguments
    + --------------------
    + highCapUsage : double
    +     minimum fraction of enzyme capacity usage to be listed as high usage
    +     (default 0.9, i.e. at least 90% capacity usage).
    + topAbsUsage : double
    +     how many top enzymes by absolute usage to list (default 10). Use 0
    +     or Inf to list all enzymes instead. Enzymes whose reactions carry no
    +     flux are never listed here, as they do not contribute to the
    +     solution.
    +
    + Returns
    + -------
    + usageReport : struct
    +     highCapUsage : table
    +         enzymes at or above the highCapUsage threshold.
    +     topAbsUsage : table
    +         the topAbsUsage enzymes with the highest absolute usage.
    +     totalUsageFlux : double
    +         total protein pool used, i.e. the upper bound of prot_pool_exchange.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     usageReport = reportEnzymeUsage(ecModel, usageData, highCapUsage, topAbsUsage);
    +     usageReport = reportEnzymeUsage(ecModel, usageData, 'topAbsUsage', 20);
    +
    + See also
    + --------
    + getEnzymeUsage
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function usageReport = reportEnzymeUsage(ecModel, usageData, varargin)
    +0002 % reportEnzymeUsage  Summarize the results from getEnzymeUsage.
    +0003 %
    +0004 % Ranks the enzymes from getEnzymeUsage into two tables: those with the
    +0005 % highest capacity usage, and those with the highest absolute usage.
    +0006 %
    +0007 % Parameters
    +0008 % ----------
    +0009 % ecModel : struct
    +0010 %     a GECKO3 ecModel.
    +0011 % usageData : struct
    +0012 %     output from getEnzymeUsage.
    +0013 %
    +0014 % Name-Value Arguments
    +0015 % --------------------
    +0016 % highCapUsage : double
    +0017 %     minimum fraction of enzyme capacity usage to be listed as high usage
    +0018 %     (default 0.9, i.e. at least 90% capacity usage).
    +0019 % topAbsUsage : double
    +0020 %     how many top enzymes by absolute usage to list (default 10). Use 0
    +0021 %     or Inf to list all enzymes instead. Enzymes whose reactions carry no
    +0022 %     flux are never listed here, as they do not contribute to the
    +0023 %     solution.
    +0024 %
    +0025 % Returns
    +0026 % -------
    +0027 % usageReport : struct
    +0028 %     highCapUsage : table
    +0029 %         enzymes at or above the highCapUsage threshold.
    +0030 %     topAbsUsage : table
    +0031 %         the topAbsUsage enzymes with the highest absolute usage.
    +0032 %     totalUsageFlux : double
    +0033 %         total protein pool used, i.e. the upper bound of prot_pool_exchange.
    +0034 %
    +0035 % Examples
    +0036 % --------
    +0037 %     % optional arguments may be given positionally or as name-value pairs:
    +0038 %     usageReport = reportEnzymeUsage(ecModel, usageData, highCapUsage, topAbsUsage);
    +0039 %     usageReport = reportEnzymeUsage(ecModel, usageData, 'topAbsUsage', 20);
    +0040 %
    +0041 % See also
    +0042 % --------
    +0043 % getEnzymeUsage
    +0044 
    +0045 p = parseGECKOargs(varargin, { ...
    +0046     'highCapUsage', []; ...
    +0047     'topAbsUsage',  []});
    +0048 highCapUsage = p.highCapUsage;
    +0049 topAbsUsage  = p.topAbsUsage;
    +0050 if isempty(highCapUsage); highCapUsage = 0.9; end
    +0051 if isempty(topAbsUsage);  topAbsUsage  = 10;  end
    +0052 % 0 or Inf means "all enzymes", per the docstring above -- and any topAbsUsage at or
    +0053 % above the enzyme count means the same thing in practice, but unlike those two special
    +0054 % values it used to reach the indexing below unclamped: usageData.protID(topUse(1:N))
    +0055 % with N > numel(topUse) is an out-of-bounds index, so any model with fewer than 10
    +0056 % enzymes (ecTestGEM has 5) crashed on the default call.
    +0057 if topAbsUsage == 0 || isinf(topAbsUsage) || topAbsUsage > numel(usageData.protID)
    +0058     topAbsUsage = numel(usageData.protID);
    +0059 end
    +0060 
    +0061 usageReport = {};
    +0062 
    +0063 % Highest capacity usage
    +0064 highUsageProt = find(usageData.capUsage > highCapUsage);
    +0065 highEnzyme    = usageData.protID(highUsageProt);
    +0066 [~,enzIdx]    = ismember(highEnzyme,ecModel.ec.enzymes);
    +0067 geneIDs       = ecModel.ec.genes(enzIdx);
    +0068 
    +0069 highUsage.protID     = {};
    +0070 highUsage.geneID     = {};
    +0071 highUsage.absUsage   = [];
    +0072 highUsage.capUsage   = [];
    +0073 highUsage.kcat       = [];
    +0074 highUsage.source     = {};
    +0075 highUsage.rxnID      = {};
    +0076 highUsage.rxnNames   = {};
    +0077 highUsage.grRules    = {};
    +0078 
    +0079 for i=1:numel(enzIdx)
    +0080     [rxns, kcat, idx, rxnNames, grRules] = getReactionsFromEnzyme(ecModel,ecModel.ec.enzymes(enzIdx(i)));
    +0081     % See if all reactions carried flux
    +0082     [~,rIdx] = ismember(rxns,ecModel.rxns);
    +0083     carriedFlux = usageData.fluxes(rIdx) > 1e-7;
    +0084     if isscalar(find(carriedFlux))
    +0085         highUsage.protID(end+1,1)      = highEnzyme(i);
    +0086         highUsage.geneID(end+1,1)      = geneIDs(i);
    +0087         highUsage.absUsage(end+1,1)    = usageData.absUsage(enzIdx(i));
    +0088         highUsage.capUsage(end+1,1)    = usageData.capUsage(enzIdx(i));
    +0089         highUsage.kcat(end+1,1)        = kcat(carriedFlux);
    +0090         highUsage.source(end+1,1)      = ecModel.ec.source(idx(carriedFlux));
    +0091         highUsage.rxnID(end+1,1)       = rxns(carriedFlux);
    +0092         highUsage.rxnNames(end+1,1)    = rxnNames(carriedFlux);
    +0093         highUsage.grRules(end+1,1)     = grRules(carriedFlux);
    +0094     else
    +0095         % Add one entry for combined usage
    +0096         highUsage.protID(end+1,1)      = highEnzyme(i);
    +0097         highUsage.geneID(end+1,1)      = geneIDs(i);
    +0098         highUsage.absUsage(end+1,1)    = usageData.absUsage(enzIdx(i));
    +0099         highUsage.capUsage(end+1,1)    = usageData.capUsage(enzIdx(i));
    +0100         highUsage.kcat(end+1,1)        = nan;
    +0101         highUsage.source{end+1,1}      = '===';
    +0102         highUsage.rxnID{end+1,1}       = '===';
    +0103         highUsage.rxnNames{end+1,1}    = 'involved in multiple rxns, usage combined, individual rxns below';
    +0104         highUsage.grRules{end+1,1}     = '===';
    +0105         % Recalculate reaction-specific usage
    +0106 
    +0107         rIdx = rIdx(carriedFlux);
    +0108         enzFlux = usageData.fluxes(rIdx);
    +0109         enzMet = strcat('prot_',highEnzyme{i});
    +0110         [~, enzEcIdx] = ismember(enzMet,ecModel.mets);
    +0111         indAbsUse = full(transpose(-ecModel.S(enzEcIdx,rIdx)).*enzFlux);
    +0112         indCapUse = (indAbsUse /sum(indAbsUse)) * usageData.capUsage(enzIdx(i));
    +0113 
    +0114         rxnNumber = length(rIdx);
    +0115         highUsage.protID(end+1:end+rxnNumber,1)      = highEnzyme(i);
    +0116         highUsage.geneID(end+1:end+rxnNumber,1)      = geneIDs(i);
    +0117         highUsage.absUsage(end+1:end+rxnNumber,1)    = indAbsUse;
    +0118         highUsage.capUsage(end+1:end+rxnNumber,1)    = indCapUse;
    +0119         highUsage.kcat(end+1:end+rxnNumber,1)        = kcat(carriedFlux);
    +0120         highUsage.source(end+1:end+rxnNumber,1)      = ecModel.ec.source(idx(carriedFlux));
    +0121         highUsage.rxnID(end+1:end+rxnNumber,1)       = rxns(carriedFlux);
    +0122         highUsage.rxnNames(end+1:end+rxnNumber,1)    = rxnNames(carriedFlux);
    +0123         highUsage.grRules(end+1:end+rxnNumber,1)     = grRules(carriedFlux);
    +0124     end    
    +0125 end
    +0126 
    +0127 usageReport.highCapUsage = struct2table(highUsage);
    +0128 
    +0129 % Highest absolute usage
    +0130 [~,topUse]          = sort(usageData.absUsage,'descend');
    +0131 topEnzyme           = usageData.protID(topUse(1:topAbsUsage));
    +0132 [~,b]       = ismember(topEnzyme,ecModel.ec.enzymes);
    +0133 geneIDs     = ecModel.ec.genes(b);
    +0134 topUsage.protID     = {};
    +0135 topUsage.geneID     = {};
    +0136 topUsage.absUsage   = [];
    +0137 topUsage.percUsage  = [];
    +0138 topUsage.kcat       = [];
    +0139 topUsage.source     = {};
    +0140 topUsage.rxnID      = {};
    +0141 topUsage.rxnNames   = {};
    +0142 topUsage.grRules    = {};
    +0143 
    +0144 protPool = ecModel.ub(strcmp(ecModel.rxns,'prot_pool_exchange'));
    +0145 
    +0146 for i=1:numel(topEnzyme)
    +0147     [rxns, kcat, idx, rxnNames, grRules] = getReactionsFromEnzyme(ecModel,topEnzyme{i});
    +0148     % See if all reactions carried flux
    +0149     [~,rIdx] = ismember(rxns,ecModel.rxns);
    +0150     carriedFlux = usageData.fluxes(rIdx) > 1e-7;
    +0151     if ~any(carriedFlux)
    +0152         % None of this enzyme's reactions carry flux -- skip it rather than
    +0153         % padding the table with a placeholder row for an enzyme that is not
    +0154         % actually active.
    +0155         continue
    +0156     elseif isscalar(find(carriedFlux))
    +0157         topUsage.protID(end+1,1)      = topEnzyme(i);
    +0158         topUsage.geneID(end+1,1)      = geneIDs(i);
    +0159         topUsage.absUsage(end+1,1)    = usageData.absUsage(topUse(i));
    +0160         topUsage.percUsage(end+1,1)   = topUsage.absUsage(end,1)/protPool*100;
    +0161         topUsage.kcat(end+1,1)        = kcat(carriedFlux);
    +0162         topUsage.source(end+1,1)      = ecModel.ec.source(idx(carriedFlux));
    +0163         topUsage.rxnID(end+1,1)       = rxns(carriedFlux);
    +0164         topUsage.rxnNames(end+1,1)    = rxnNames(carriedFlux);
    +0165         topUsage.grRules(end+1,1)     = grRules(carriedFlux);
    +0166     else
    +0167         % Add one entry for combined usage
    +0168         topUsage.protID(end+1,1)      = topEnzyme(i);
    +0169         topUsage.geneID(end+1,1)      = geneIDs(i);
    +0170         topUsage.absUsage(end+1,1)    = usageData.absUsage(topUse(i));
    +0171         topUsage.percUsage(end+1,1)   = topUsage.absUsage(end,1)/protPool*100;
    +0172         topUsage.kcat(end+1,1)        = nan;
    +0173         topUsage.source{end+1,1}      = '===';
    +0174         topUsage.rxnID{end+1,1}       = '===';
    +0175         topUsage.rxnNames{end+1,1}    = 'involved in multiple rxns, usage combined, individual rxns below';
    +0176         topUsage.grRules{end+1,1}     = '===';
    +0177         % Recalculate reaction-specific usage
    +0178         rIdx = rIdx(carriedFlux);
    +0179         enzFlux = usageData.fluxes(rIdx);
    +0180         enzMet = strcat('prot_',topEnzyme{i});
    +0181         [~, enzIdx] = ismember(enzMet,ecModel.mets);
    +0182         indUse = full(transpose(-ecModel.S(enzIdx,rIdx)).*enzFlux);
    +0183         rxnNumber = length(rIdx);
    +0184         topUsage.protID(end+1:end+rxnNumber,1)      = topEnzyme(i);
    +0185         topUsage.geneID(end+1:end+rxnNumber,1)      = geneIDs(i);
    +0186         topUsage.absUsage(end+1:end+rxnNumber,1)    = indUse;
    +0187         topUsage.percUsage(end+1:end+rxnNumber,1)   = topUsage.absUsage(end-(rxnNumber-1):end,1)/protPool*100;
    +0188         topUsage.kcat(end+1:end+rxnNumber,1)        = kcat(carriedFlux);
    +0189         topUsage.source(end+1:end+rxnNumber,1)      = ecModel.ec.source(idx(carriedFlux));
    +0190         topUsage.rxnID(end+1:end+rxnNumber,1)       = rxns(carriedFlux);
    +0191         topUsage.rxnNames(end+1:end+rxnNumber,1)    = rxnNames(carriedFlux);
    +0192         topUsage.grRules(end+1:end+rxnNumber,1)     = grRules(carriedFlux);
    +0193     end
    +0194 end
    +0195 usageReport.topAbsUsage     = struct2table(topUsage);
    +0196 usageReport.totalUsageFlux  = protPool;
    +0197 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/flux_analysis/ecFSEOF.html b/doc/src/flux_analysis/ecFSEOF.html new file mode 100644 index 00000000..2db4959d --- /dev/null +++ b/doc/src/flux_analysis/ecFSEOF.html @@ -0,0 +1,457 @@ + + + + Description of ecFSEOF + + + + + + + + + +
    Home > src > flux_analysis > ecFSEOF.m
    + + + +

    ecFSEOF +

    + +

    PURPOSE ^

    +
    ecFSEOF Run Flux-Scanning with Enforced Objective Function for a target.
    + +

    SYNOPSIS ^

    +
    function fseof = ecFSEOF(model,prodTargetRxn,csRxn,varargin)
    + +

    DESCRIPTION ^

    +
     ecFSEOF  Run Flux-Scanning with Enforced Objective Function for a target.
    +
    + Runs Flux-Scanning with Enforced Objective Function (FSEOF) for a
    + specified production target, to identify reaction and gene targets for
    + metabolic engineering. Reactions are classified as targets with the same
    + rule as RAVEN's FSEOF: the correlation between the absolute flux of a
    + reaction and the enforced production flux.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    + prodTargetRxn : char
    +     rxn ID for the production target reaction, an exchange reaction is
    +     recommended.
    + csRxn : char
    +     rxn ID for the main carbon source uptake reaction.
    +
    + Name-Value Arguments
    + --------------------
    + nSteps : double
    +     number of steps for suboptimal objective in FSEOF (default 16).
    + outputFile : logical
    +     boolean option to save results in a file (default false).
    + filePath : char
    +     file path for results output. It will store two files: at the genes
    +     level, ecFSEOF_genes.tsv; and at the reactions level,
    +     ecFSEOF_rxns.tsv (default: the 'output' sub-folder taken from
    +     modelAdapter, e.g. output/ecFSEOF_rxns.tsv).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + corrThreshold : double
    +     minimum absolute Pearson correlation between the absolute flux of a
    +     reaction and the enforced production flux for the reaction to be a
    +     target (default 0.9).
    +
    + Returns
    + -------
    + fseof : struct
    +     a structure with all results.
    +
    + Notes
    + -----
    + The fseof structure has the following fields:
    +
    + - alpha : target production used for enforced objective limits (from minimum to maximum production).
    + - v_matrix : fluxes for each target reaction predicted and each alpha.
    + - rxnTargets : a list with all reactions whose absolute flux is correlated with the enforced production, with an absolute correlation of at least corrThreshold. Contains ID, name, slope, gene rule, and equation. The slope is the absolute slope of the regression of the absolute flux on the enforced production flux. The list is ordered by the product of slope and correlation, highest first.
    + - transportTargets : the same for transport reactions.
    + - geneTargets : a list with all genes of the targets. Contains gene, shortName, slope, action, and essentiality.
    +
    + Only reactions with a gene rule are considered, and not those that are
    + assigned to the standard enzyme. The enforced production reaction is
    + included when it has a gene rule, as its flux follows the enforced
    + production by definition. The reactions that draw enzyme usage
    + (usage_prot_*) take part in the classification and are not reported.
    + A reaction is over expressed (OE) when its flux increases with production,
    + knocked out (KO) when it decreases and is at most 1e-8 at the last step,
    + and knocked down (KD) when it decreases otherwise.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     fseof = ecFSEOF(model,prodTargetRxn,csRxn,nSteps,outputFile,filePath,modelAdapter,corrThreshold);
    +     fseof = ecFSEOF(model,prodTargetRxn,csRxn,'nSteps',32);
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function fseof = ecFSEOF(model,prodTargetRxn,csRxn,varargin)
    +0002 % ecFSEOF  Run Flux-Scanning with Enforced Objective Function for a target.
    +0003 %
    +0004 % Runs Flux-Scanning with Enforced Objective Function (FSEOF) for a
    +0005 % specified production target, to identify reaction and gene targets for
    +0006 % metabolic engineering. Reactions are classified as targets with the same
    +0007 % rule as RAVEN's FSEOF: the correlation between the absolute flux of a
    +0008 % reaction and the enforced production flux.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % model : struct
    +0013 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0014 % prodTargetRxn : char
    +0015 %     rxn ID for the production target reaction, an exchange reaction is
    +0016 %     recommended.
    +0017 % csRxn : char
    +0018 %     rxn ID for the main carbon source uptake reaction.
    +0019 %
    +0020 % Name-Value Arguments
    +0021 % --------------------
    +0022 % nSteps : double
    +0023 %     number of steps for suboptimal objective in FSEOF (default 16).
    +0024 % outputFile : logical
    +0025 %     boolean option to save results in a file (default false).
    +0026 % filePath : char
    +0027 %     file path for results output. It will store two files: at the genes
    +0028 %     level, ecFSEOF_genes.tsv; and at the reactions level,
    +0029 %     ecFSEOF_rxns.tsv (default: the 'output' sub-folder taken from
    +0030 %     modelAdapter, e.g. output/ecFSEOF_rxns.tsv).
    +0031 % modelAdapter : ModelAdapter
    +0032 %     a loaded model adapter (default: the current default model adapter).
    +0033 % corrThreshold : double
    +0034 %     minimum absolute Pearson correlation between the absolute flux of a
    +0035 %     reaction and the enforced production flux for the reaction to be a
    +0036 %     target (default 0.9).
    +0037 %
    +0038 % Returns
    +0039 % -------
    +0040 % fseof : struct
    +0041 %     a structure with all results.
    +0042 %
    +0043 % Notes
    +0044 % -----
    +0045 % The fseof structure has the following fields:
    +0046 %
    +0047 % - alpha : target production used for enforced objective limits (from minimum to maximum production).
    +0048 % - v_matrix : fluxes for each target reaction predicted and each alpha.
    +0049 % - rxnTargets : a list with all reactions whose absolute flux is correlated with the enforced production, with an absolute correlation of at least corrThreshold. Contains ID, name, slope, gene rule, and equation. The slope is the absolute slope of the regression of the absolute flux on the enforced production flux. The list is ordered by the product of slope and correlation, highest first.
    +0050 % - transportTargets : the same for transport reactions.
    +0051 % - geneTargets : a list with all genes of the targets. Contains gene, shortName, slope, action, and essentiality.
    +0052 %
    +0053 % Only reactions with a gene rule are considered, and not those that are
    +0054 % assigned to the standard enzyme. The enforced production reaction is
    +0055 % included when it has a gene rule, as its flux follows the enforced
    +0056 % production by definition. The reactions that draw enzyme usage
    +0057 % (usage_prot_*) take part in the classification and are not reported.
    +0058 % A reaction is over expressed (OE) when its flux increases with production,
    +0059 % knocked out (KO) when it decreases and is at most 1e-8 at the last step,
    +0060 % and knocked down (KD) when it decreases otherwise.
    +0061 %
    +0062 % Examples
    +0063 % --------
    +0064 %     % optional arguments may be given positionally or as name-value pairs:
    +0065 %     fseof = ecFSEOF(model,prodTargetRxn,csRxn,nSteps,outputFile,filePath,modelAdapter,corrThreshold);
    +0066 %     fseof = ecFSEOF(model,prodTargetRxn,csRxn,'nSteps',32);
    +0067 
    +0068 p = parseGECKOargs(varargin, { ...
    +0069     'nSteps',       16; ...
    +0070     'outputFile',   false; ...
    +0071     'filePath',     []; ...
    +0072     'modelAdapter', []; ...
    +0073     'corrThreshold',0.9});
    +0074 nSteps       = p.nSteps;
    +0075 outputFile   = p.outputFile;
    +0076 filePath     = p.filePath;
    +0077 modelAdapter  = p.modelAdapter;
    +0078 corrThreshold = p.corrThreshold;
    +0079 
    +0080 if isempty(modelAdapter)
    +0081     modelAdapter = ModelAdapterManager.getDefault();
    +0082     if isempty(modelAdapter)
    +0083         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0084     end
    +0085 end
    +0086 params = modelAdapter.getParameters();
    +0087 
    +0088 if isempty(filePath)
    +0089     filePath = fullfile(params.path,'output');
    +0090 end
    +0091 
    +0092 % Get relevant rxn indexes
    +0093 prodTargetRxnIdx = getIndexes(model, prodTargetRxn,'rxns');
    +0094 csRxnIdx         = getIndexes(model, csRxn,'rxns');
    +0095 bioRxnIdx        = getIndexes(model, params.bioRxn,'rxns');
    +0096 
    +0097 % Standardize grRules and rxnGeneMat in model
    +0098 [grRules,rxnGeneMat] = standardizeGrRules(model,true);
    +0099 model.grRules        = grRules;
    +0100 model.rxnGeneMat     = rxnGeneMat;
    +0101 
    +0102 % Check carbon source uptake rate and LB defined
    +0103 model = setParam(model, 'obj', params.bioRxn, 1);
    +0104 sol   = solveLP(model);
    +0105 if model.lb(csRxnIdx) < sol.x(csRxnIdx)
    +0106     printOrange(['WARNING: Carbon source lower bound was set to ' num2str(model.lb(csRxnIdx)) ...
    +0107         ', but the uptake rate after model optimization is ' num2str(sol.x(csRxnIdx)) '.\n']);
    +0108 end
    +0109 
    +0110 % run FSEOF analysis
    +0111 
    +0112 % Find out the initial target production.
    +0113 iniTarget = sol.x(prodTargetRxnIdx);
    +0114 
    +0115 % Find out the maximum theoretical yield of target reaction.
    +0116 model     = setParam(model,'obj',prodTargetRxn,1);
    +0117 sol       = solveLP(model,1);
    +0118 % Set to 90%% based on https://doi.org/10.1128/AEM.00115-10
    +0119 maxTarget = sol.x(prodTargetRxnIdx) * 0.9;
    +0120 
    +0121 % Define alpha vector for suboptimal enforced objective values between
    +0122 % minimal production and 90%% of the maximum theoretical yield, initialize
    +0123 % fluxes matriz
    +0124 alpha    = iniTarget:((maxTarget-iniTarget)/(nSteps-1)):maxTarget;
    +0125 v_matrix = zeros(length(model.rxns),length(alpha));
    +0126 
    +0127 % Enforce objective flux iteratively
    +0128 PB = progressReport(nSteps, 'Flux Scanning with Enforced Objective Function');
    +0129 for i = 1:nSteps
    +0130     PB.count;
    +0131     % Enforce the objetive flux of product formation
    +0132     model = setParam(model,'eq',prodTargetRxnIdx,alpha(i));
    +0133 
    +0134     % Restore minimum biomass lb to zero and set it as objective
    +0135     model.lb(bioRxnIdx) = 0;
    +0136     model = setParam(model,'obj',params.bioRxn,1);
    +0137     sol   = solveLP(model,1);
    +0138 
    +0139     % Store flux distribution
    +0140     v_matrix(:,i) = sol.x;
    +0141 
    +0142 end
    +0143 PB.done;
    +0144 
    +0145 % Take out rxns with no grRule and standard gene
    +0146 withGR         = ~cellfun(@isempty,model.grRules);
    +0147 stdIdx         = contains(model.grRules,'standard');
    +0148 withGR(stdIdx) = 0;
    +0149 target_rxns    = model.rxns(withGR);
    +0150 v_matrix       = v_matrix(withGR,:);
    +0151 rxnGeneM       = model.rxnGeneMat(withGR,:);
    +0152 
    +0153 % Classify the reactions as in RAVEN's FSEOF. Slope and correlation are taken
    +0154 % on the absolute flux against the enforced production flux, so a reversible
    +0155 % reaction running backwards counts by its magnitude. A reaction is a target
    +0156 % when some absolute flux exceeds 1e-10, the standard deviation of its
    +0157 % absolute flux is above 0 and the absolute Pearson correlation reaches
    +0158 % corrThreshold. It is suggested for over expression (OE) when the slope is
    +0159 % positive, for knock out (KO) when the slope is negative and the absolute
    +0160 % flux at the last step is at most 1e-8, and for knock down (KD) for any
    +0161 % other negative slope.
    +0162 absV        = abs(v_matrix);
    +0163 slope_rxns  = zeros(size(target_rxns));
    +0164 corr_rxns   = zeros(size(target_rxns));
    +0165 target_type = cell(size(target_rxns));
    +0166 targets     = false(size(target_rxns));
    +0167 if numel(alpha) > 1 && std(alpha) > 0
    +0168     for i = 1:length(target_rxns)
    +0169         track = absV(i,:);
    +0170         if any(track > 1e-10) && std(track) > 0
    +0171             fit = polyfit(alpha,track,1);
    +0172             r   = corrcoef(alpha,track);
    +0173             if abs(r(1,2)) >= corrThreshold && fit(1) ~= 0
    +0174                 targets(i)     = true;
    +0175                 slope_rxns(i)  = abs(fit(1));
    +0176                 corr_rxns(i)   = abs(r(1,2));
    +0177                 if fit(1) > 0
    +0178                     target_type(i) = {'OE'};
    +0179                 elseif track(end) <= 1e-8
    +0180                     target_type(i) = {'KO'};
    +0181                 else
    +0182                     target_type(i) = {'KD'};
    +0183                 end
    +0184             end
    +0185         end
    +0186     end
    +0187 end
    +0188 
    +0189 % Only keep those reactions that are classified as a target
    +0190 target_rxns = target_rxns(targets);
    +0191 v_matrix    = v_matrix(targets,:);
    +0192 rxnGeneM    = rxnGeneM(targets,:);
    +0193 slope_rxns  = slope_rxns(targets);
    +0194 corr_rxns   = corr_rxns(targets);
    +0195 target_type = target_type(targets);
    +0196 
    +0197 % Order from highest to lowest score, the product of slope and correlation
    +0198 [~,order]   = sort(slope_rxns .* corr_rxns,'descend');
    +0199 target_rxns = target_rxns(order);
    +0200 v_matrix    = v_matrix(order,:);
    +0201 rxnGeneM    = rxnGeneM(order,:);
    +0202 slope_rxns  = slope_rxns(order);
    +0203 target_type = target_type(order);
    +0204 
    +0205 % Exclude enzyme usage reactions: they are not reported, and they would otherwise
    +0206 % enter the gene slopes and the choice of the action per gene
    +0207 notUsage    = ~startsWith(target_rxns,'usage_prot_');
    +0208 target_rxns = target_rxns(notUsage);
    +0209 v_matrix    = v_matrix(notUsage,:);
    +0210 rxnGeneM    = rxnGeneM(notUsage,:);
    +0211 slope_rxns  = slope_rxns(notUsage);
    +0212 target_type = target_type(notUsage);
    +0213 
    +0214 % Create gene list of those connected to the remaining rxns
    +0215 genes             = model.genes(sum(rxnGeneM,1) > 0);
    +0216 slope_genes       = zeros(size(genes));
    +0217 rxnGeneM          = rxnGeneM(:,sum(rxnGeneM,1) > 0);
    +0218 target_type_genes = cell(size(genes));
    +0219 essentiality      = cell(size(genes));
    +0220 
    +0221 % Validate for gene essentiality
    +0222 PB = progressReport(numel(genes), 'Checking for gene essentiality');
    +0223 for i = 1:numel(genes)
    +0224     PB.count;
    +0225 
    +0226     % Block protein usage to KO al the reactions associated to it.
    +0227     usage_rxn_idx = strcmpi(model.ec.genes, genes{i});
    +0228     usage_rxn = strcat('usage_prot_', model.ec.enzymes(usage_rxn_idx));
    +0229     tempModel = setParam(model, 'eq', usage_rxn, 0);
    +0230     solKO     = solveLP(tempModel);
    +0231     % Check if no feasible solution was found
    +0232     if solKO.stat == -1 || solKO.x(bioRxnIdx) < 1e-8
    +0233         essentiality(i) = {'essential'};
    +0234     end
    +0235 
    +0236     % Since a gene can be involved in multiple reactions, multiple
    +0237     % engineering manipulations can be suggested for the same gene
    +0238     % e.g. (OE and KD). So, reconcilie them, and report only one.
    +0239     
    +0240     % Get reaction index, in targets set, for each gene
    +0241     rxns_for_gene = find(rxnGeneM(:,i) > 0);
    +0242     actions = unique(target_type(rxns_for_gene));
    +0243     if numel(actions) > 1
    +0244         % If any OE is suggested give the highest priority over KD or KO
    +0245         if any(startsWith(actions, 'OE'))
    +0246             target_type_genes(i) = {'OE'};
    +0247             % Otherwise change to KO if not essential
    +0248         elseif ~any(startsWith(actions, 'OE')) && ~isequal(essentiality(i),{'essential'})
    +0249             target_type_genes(i) = {'KO'};
    +0250         else
    +0251             target_type_genes(i) = {'KD'};
    +0252         end
    +0253     else
    +0254         target_type_genes(i) = actions;
    +0255     end
    +0256     % Extract all the slope (from rxns across alphas) conected to
    +0257     % each remaining gene
    +0258     slope_set      = slope_rxns(rxns_for_gene);
    +0259     slope_genes(i) = mean(slope_set);
    +0260 
    +0261 end
    +0262 PB.done;
    +0263 
    +0264 % Order genes from highest to lowest slope:
    +0265 [~,order]         = sort(slope_genes,'descend');
    +0266 genes             = genes(order,:);
    +0267 slope_genes       = slope_genes(order,:);
    +0268 target_type_genes = target_type_genes(order,:);
    +0269 essentiality      = essentiality(order,:);
    +0270 
    +0271 % Create output:
    +0272 
    +0273 % Report values used to enforce objective target production
    +0274 fseof.alpha = alpha;
    +0275 
    +0276 rxnIdx = getIndexes(model,target_rxns,'rxns');
    +0277 
    +0278 % Report the fluxes at each alpha
    +0279 fseof.v_matrix = array2table(v_matrix, ...
    +0280     'VariableNames', string(alpha), 'RowNames', model.rxns(rxnIdx));
    +0281 
    +0282 % Report reaction targets
    +0283 fseof.rxnTargets(:,1) = model.rxns(rxnIdx);
    +0284 fseof.rxnTargets(:,2) = model.rxnNames(rxnIdx);
    +0285 fseof.rxnTargets(:,3) = num2cell(slope_rxns);
    +0286 fseof.rxnTargets(:,4) = model.grRules(rxnIdx);
    +0287 if isempty(rxnIdx)
    +0288     fseof.rxnTargets(:,5) = cell(0,1); % constructEquations would give all reactions
    +0289 else
    +0290     fseof.rxnTargets(:,5) = constructEquations(model,rxnIdx);
    +0291 end
    +0292 
    +0293 % Identify transport reactions; defined as reactions involving (at least)
    +0294 % one metabolite name in more than one compartment.
    +0295 transportRxns = false(numel(rxnIdx),1);
    +0296 for i = 1:numel(rxnIdx)
    +0297     % Get the involved metabolites in each reaction
    +0298     mets = model.metNames(model.S(:,rxnIdx(i))~=0);
    +0299     % Remove enzyme metabolite
    +0300     mets(startsWith(mets,'prot_')) = [];
    +0301     % Validate if it is a transport reaciton
    +0302     transportRxns(i) = numel(mets) ~= numel(unique(mets));
    +0303 end
    +0304 
    +0305 % Create separate table for transport reactions
    +0306 fseof.transportTargets = fseof.rxnTargets(transportRxns,:);
    +0307 fseof.rxnTargets(transportRxns,:) = [];
    +0308 
    +0309 % Report gene targets
    +0310 geneIdx              = cellfun(@(x) find(strcmpi(model.genes,x)),genes);
    +0311 fseof.geneTargets(:,1) = genes;
    +0312 fseof.geneTargets(:,2) = model.geneShortNames(geneIdx);
    +0313 fseof.geneTargets(:,3) = num2cell(slope_genes);
    +0314 fseof.geneTargets(:,4) = target_type_genes;
    +0315 fseof.geneTargets(:,5) = essentiality;
    +0316 
    +0317 % Save results in a file if defined
    +0318 if outputFile
    +0319     % Write file with gene targets
    +0320     writetable(cell2table(fseof.geneTargets, ...
    +0321         'VariableNames', {'gene_IDs' 'gene_names' 'slope' 'action' 'essentiality'}), ...
    +0322         fullfile(filePath, 'ecFSEOF_genes.tsv'), ...
    +0323         'FileType', 'text', ...
    +0324         'Delimiter', '\t', ...
    +0325         'QuoteStrings', false);
    +0326 
    +0327     % Write file with rxn targets
    +0328     writetable(cell2table(fseof.rxnTargets, ...
    +0329         'VariableNames', {'rxn_IDs' 'rxnNames' 'slope' 'grRules' 'rxn_formula'}), ...
    +0330         fullfile(filePath, 'ecFSEOF_rxns.tsv'), ...
    +0331         'FileType', 'text', ...
    +0332         'Delimiter', '\t', ...
    +0333         'QuoteStrings', false);
    +0334 
    +0335     % Write file with transport targets
    +0336     writetable(cell2table(fseof.transportTargets, ...
    +0337         'VariableNames', {'rxn_IDs' 'rxnNames' 'slope' 'grRules' 'rxn_formula'}), ...
    +0338         fullfile(filePath, 'ecFSEOF_transporter.tsv'), ...
    +0339         'FileType', 'text', ...
    +0340         'Delimiter', '\t', ...
    +0341         'QuoteStrings', false);
    +0342 
    +0343     disp(['ecFSEOF results stored at: ' newline filePath]);
    +0344 end
    +0345 
    +0346 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/flux_analysis/ecFVA.html b/doc/src/flux_analysis/ecFVA.html new file mode 100644 index 00000000..0dc2355f --- /dev/null +++ b/doc/src/flux_analysis/ecFVA.html @@ -0,0 +1,188 @@ + + + + Description of ecFVA + + + + + + + + + +
    Home > src > flux_analysis > ecFVA.m
    + + + +

    ecFVA +

    + +

    PURPOSE ^

    +
    ecFVA Run flux variability analysis on an ecModel.
    + +

    SYNOPSIS ^

    +
    function [minFlux, maxFlux] = ecFVA(ecModel, model, varargin)
    + +

    DESCRIPTION ^

    +
     ecFVA  Run flux variability analysis on an ecModel.
    +
    + Flux variability analysis is performed on the ecModel, and isozymic
    + reactions are combined to construct output minFlux and maxFlux vectors,
    + which follow the same order of model.rxns. The output from this function
    + does not include enzyme usage reactions; to observe these, one could
    + consider running flux variability directly on the ecModel.
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    + model : struct
    +     non-ecModel variant of the ecModel, to which the minFlux and maxFlux
    +     will be mapped.
    +
    + Name-Value Arguments
    + --------------------
    + runParallel : logical
    +     speed up calculations by parallel processing. Requires the MATLAB
    +     Parallel Computing Toolbox. If this is not installed, the
    +     calculations will not be parallelized, regardless of what is
    +     indicated as runParallel (default true).
    +
    + Returns
    + -------
    + minFlux : double
    +     vector of minimum flux rates, corresponding to model.rxns.
    + maxFlux : double
    +     vector of maximum flux rates, corresponding to model.rxns.
    +
    + Examples
    + --------
    +     [minFlux, maxFlux] = ecFVA(ecModel, model);
    +
    + See also
    + --------
    + mapRxnsToConv, plotEcFVA
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function [minFlux, maxFlux] = ecFVA(ecModel, model, varargin)
    +0002 % ecFVA  Run flux variability analysis on an ecModel.
    +0003 %
    +0004 % Flux variability analysis is performed on the ecModel, and isozymic
    +0005 % reactions are combined to construct output minFlux and maxFlux vectors,
    +0006 % which follow the same order of model.rxns. The output from this function
    +0007 % does not include enzyme usage reactions; to observe these, one could
    +0008 % consider running flux variability directly on the ecModel.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % ecModel : struct
    +0013 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0014 % model : struct
    +0015 %     non-ecModel variant of the ecModel, to which the minFlux and maxFlux
    +0016 %     will be mapped.
    +0017 %
    +0018 % Name-Value Arguments
    +0019 % --------------------
    +0020 % runParallel : logical
    +0021 %     speed up calculations by parallel processing. Requires the MATLAB
    +0022 %     Parallel Computing Toolbox. If this is not installed, the
    +0023 %     calculations will not be parallelized, regardless of what is
    +0024 %     indicated as runParallel (default true).
    +0025 %
    +0026 % Returns
    +0027 % -------
    +0028 % minFlux : double
    +0029 %     vector of minimum flux rates, corresponding to model.rxns.
    +0030 % maxFlux : double
    +0031 %     vector of maximum flux rates, corresponding to model.rxns.
    +0032 %
    +0033 % Examples
    +0034 % --------
    +0035 %     [minFlux, maxFlux] = ecFVA(ecModel, model);
    +0036 %
    +0037 % See also
    +0038 % --------
    +0039 % mapRxnsToConv, plotEcFVA
    +0040 
    +0041 p = parseGECKOargs(varargin, { ...
    +0042     'runParallel', true});
    +0043 runParallel = p.runParallel;
    +0044 
    +0045 rxnIDs = regexprep(ecModel.rxns,'(_REV)?(_EXP_\d+)?$','');
    +0046 [rxnIDmap, convRxnID] = findgroups(rxnIDs);
    +0047 
    +0048 N = numel(convRxnID);
    +0049 maxFluxByGroup = nan(N,1);
    +0050 minFluxByGroup = nan(N,1);
    +0051 
    +0052 % nW == 0 forces parfor to run as a plain for loop (no pool required or
    +0053 % created); nW == Inf lets Parallel Computing Toolbox manage the pool.
    +0054 % Falls back to serial automatically when the toolbox isn't installed,
    +0055 % rather than erroring the way an unconditional gcp/parpool call would.
    +0056 nW = parallelWorkersRAVEN(runParallel);
    +0057 
    +0058 PB = progressReport(N, 'Running ecFVA');
    +0059 
    +0060 parfor (i=1:N, nW)
    +0061     tmpModel = ecModel;
    +0062     tmpModel.c = zeros(numel(tmpModel.rxns),1);
    +0063 
    +0064     rxnsToOptim = find(rxnIDmap == i);
    +0065     rxnsOptIDs  = ecModel.rxns(rxnsToOptim);
    +0066     rxnsToMin = endsWith(rxnsOptIDs,'_REV') | contains(rxnsOptIDs,'_REV_EXP_');
    +0067     rxnsToMax = rxnsToOptim(~rxnsToMin);
    +0068     rxnsToMin = rxnsToOptim(rxnsToMin);
    +0069 
    +0070     tmpModel.c(rxnsToMax) = 1;
    +0071     tmpModel.c(rxnsToMin) = -1;
    +0072     solMax=solveLP(tmpModel);
    +0073     if ~isempty(solMax.x)
    +0074         % Exact bound for this canonical reaction, read directly off this
    +0075         % group's own solve (the "diagonal"): forward minus reverse
    +0076         % variants from the one LP that jointly optimised them, not the
    +0077         % best value each variant happened to reach in whichever group's
    +0078         % solve maximised it -- an "envelope" that can combine values from
    +0079         % different, not necessarily jointly feasible, flux distributions.
    +0080         maxFluxByGroup(i) = sum(solMax.x(rxnsToMax)) - sum(solMax.x(rxnsToMin));
    +0081     end
    +0082     tmpModel.c(rxnsToMax) = -1;
    +0083     tmpModel.c(rxnsToMin) = 1;
    +0084     solMin=solveLP(tmpModel);
    +0085     if ~isempty(solMin.x)
    +0086         minFluxByGroup(i) = sum(solMin.x(rxnsToMax)) - sum(solMin.x(rxnsToMin));
    +0087     end
    +0088     count(PB);
    +0089 end
    +0090 PB.done;
    +0091 
    +0092 % Reorder from canonical-id order to model.rxns order. No min/max swap
    +0093 % correction is needed here (unlike a row-reduced envelope): both bounds
    +0094 % come from the same group's LP over the same feasible region with only
    +0095 % the objective direction flipped, so minFluxByGroup(i) <= maxFluxByGroup(i)
    +0096 % always holds whenever both solves succeeded.
    +0097 [mapCheck, origIdx] = ismember(model.rxns, convRxnID);
    +0098 if ~all(mapCheck)
    +0099     error('Not all reactions from model.rxns can be found in the ecModel. Are you sure that ecModel is derived from model?')
    +0100 end
    +0101 minFlux = minFluxByGroup(origIdx);
    +0102 maxFlux = maxFluxByGroup(origIdx);
    +0103 
    +0104 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/flux_analysis/getPfbaEnzymes.html b/doc/src/flux_analysis/getPfbaEnzymes.html new file mode 100644 index 00000000..f848d076 --- /dev/null +++ b/doc/src/flux_analysis/getPfbaEnzymes.html @@ -0,0 +1,210 @@ + + + + Description of getPfbaEnzymes + + + + + + + + + +
    Home > src > flux_analysis > getPfbaEnzymes.m
    + + + +

    getPfbaEnzymes +

    + +

    PURPOSE ^

    +
    getPfbaEnzymes Parsimonious FBA minimising total enzyme usage.
    + +

    SYNOPSIS ^

    +
    function solution = getPfbaEnzymes(model, varargin)
    + +

    DESCRIPTION ^

    +
     getPfbaEnzymes  Parsimonious FBA minimising total enzyme usage.
    +
    + Among all flux distributions at (or within a fraction of) the optimal
    + value of the current objective, finds the one that minimises total
    + enzyme usage: the smallest sum of usage_prot_* fluxes. This is the
    + enzyme-aware analogue of classical pFBA, which minimises total flux
    + instead --- for ecModels this usually picks the most parsimonious
    + *proteome*, not just the most parsimonious fluxes.
    +
    + Parameters
    + ----------
    + model : struct
    +     a full ecModel in GECKO 3 format (with ecModel.ec structure and
    +     usage_prot_<id> reactions). Not supported for gecko-light models.
    +
    + Name-Value Arguments
    + --------------------
    + rxnId : char
    +     reaction id to use as the objective instead of model.c as given
    +     (default: use model.c as given).
    + fractionOfOptimum : double
    +     fraction of the optimal objective value to fix before minimising
    +     enzyme usage (default 1.0).
    +
    + Returns
    + -------
    + solution : struct
    +     - x : flux distribution (indexed by model.rxns) at the
    +       enzyme-usage-minimising solution.
    +     - getEnzymeUsage : the minimised sum of usage_prot_* fluxes.
    +     - objectiveValue : the fixed objective's own value at this solution.
    +     - stat : solveLP exit flag.
    +
    + Examples
    + --------
    +     solution = getPfbaEnzymes(ecModel);
    +     solution = getPfbaEnzymes(ecModel, 'fractionOfOptimum', 0.9);
    +
    + Notes
    + -----
    + usage_prot_<id> reactions must be forward-only (lb=0), the standard
    + GECKO 3 layout; if any has a negative lower bound (reverse flux enabled),
    + getPfbaEnzymes errors instead of building an objective that would fail to
    + minimise |flux| for that reaction.
    +
    + See also
    + --------
    + getEnzymeBottlenecks
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function solution = getPfbaEnzymes(model, varargin)
    +0002 % getPfbaEnzymes  Parsimonious FBA minimising total enzyme usage.
    +0003 %
    +0004 % Among all flux distributions at (or within a fraction of) the optimal
    +0005 % value of the current objective, finds the one that minimises total
    +0006 % enzyme usage: the smallest sum of usage_prot_* fluxes. This is the
    +0007 % enzyme-aware analogue of classical pFBA, which minimises total flux
    +0008 % instead --- for ecModels this usually picks the most parsimonious
    +0009 % *proteome*, not just the most parsimonious fluxes.
    +0010 %
    +0011 % Parameters
    +0012 % ----------
    +0013 % model : struct
    +0014 %     a full ecModel in GECKO 3 format (with ecModel.ec structure and
    +0015 %     usage_prot_<id> reactions). Not supported for gecko-light models.
    +0016 %
    +0017 % Name-Value Arguments
    +0018 % --------------------
    +0019 % rxnId : char
    +0020 %     reaction id to use as the objective instead of model.c as given
    +0021 %     (default: use model.c as given).
    +0022 % fractionOfOptimum : double
    +0023 %     fraction of the optimal objective value to fix before minimising
    +0024 %     enzyme usage (default 1.0).
    +0025 %
    +0026 % Returns
    +0027 % -------
    +0028 % solution : struct
    +0029 %     - x : flux distribution (indexed by model.rxns) at the
    +0030 %       enzyme-usage-minimising solution.
    +0031 %     - getEnzymeUsage : the minimised sum of usage_prot_* fluxes.
    +0032 %     - objectiveValue : the fixed objective's own value at this solution.
    +0033 %     - stat : solveLP exit flag.
    +0034 %
    +0035 % Examples
    +0036 % --------
    +0037 %     solution = getPfbaEnzymes(ecModel);
    +0038 %     solution = getPfbaEnzymes(ecModel, 'fractionOfOptimum', 0.9);
    +0039 %
    +0040 % Notes
    +0041 % -----
    +0042 % usage_prot_<id> reactions must be forward-only (lb=0), the standard
    +0043 % GECKO 3 layout; if any has a negative lower bound (reverse flux enabled),
    +0044 % getPfbaEnzymes errors instead of building an objective that would fail to
    +0045 % minimise |flux| for that reaction.
    +0046 %
    +0047 % See also
    +0048 % --------
    +0049 % getEnzymeBottlenecks
    +0050 
    +0051 p = parseGECKOargs(varargin, {'rxnId', []; 'fractionOfOptimum', []});
    +0052 rxnId             = p.rxnId;
    +0053 fractionOfOptimum = p.fractionOfOptimum;
    +0054 if isempty(fractionOfOptimum)
    +0055     fractionOfOptimum = 1.0;
    +0056 end
    +0057 
    +0058 if isfield(model.ec, 'geckoLight') && model.ec.geckoLight
    +0059     error(['getPfbaEnzymes requires a full ecModel, not gecko-light: light models have no ' ...
    +0060         'usage_prot_<id> reactions.'])
    +0061 end
    +0062 
    +0063 if ~isempty(rxnId)
    +0064     rxnIdx = find(strcmp(model.rxns, rxnId));
    +0065     if isempty(rxnIdx)
    +0066         error('getPfbaEnzymes: reaction %s not found in model.rxns.', rxnId)
    +0067     end
    +0068     model.c = zeros(numel(model.rxns), 1);
    +0069     model.c(rxnIdx) = 1;
    +0070 end
    +0071 if ~any(model.c)
    +0072     error('getPfbaEnzymes: model.c is empty; nothing to fix before minimising enzyme usage.')
    +0073 end
    +0074 
    +0075 usageIdx = find(startsWith(model.rxns, 'usage_prot_'));
    +0076 if isempty(usageIdx)
    +0077     error('getPfbaEnzymes: no usage_prot_<id> reactions found. This is done by makeEcModel.')
    +0078 end
    +0079 if any(model.lb(usageIdx) < 0)
    +0080     error(['getPfbaEnzymes does not support usage_prot_<id> reactions with a negative lower ' ...
    +0081         'bound (reverse flux enabled): minimising raw flux would not minimise |flux| for ' ...
    +0082         'those reactions.'])
    +0083 end
    +0084 
    +0085 solOrig = solveLP(model);
    +0086 if solOrig.stat ~= 1
    +0087     error('getPfbaEnzymes: solver status %d on the original objective; cannot fix it as a constraint.', solOrig.stat)
    +0088 end
    +0089 
    +0090 % Fix the objective as a constraint, same "fake metabolite" technique
    +0091 % solveLP's own minFlux=1 option uses (see solveLP.m).
    +0092 target = fractionOfOptimum * solOrig.f;
    +0093 if target > 0
    +0094     target = target * 0.999999;
    +0095 else
    +0096     target = target * 1.000001;
    +0097 end
    +0098 fixModel = model;
    +0099 fixModel.S(end+1, :) = model.c';
    +0100 fixModel.mets{end+1, 1} = 'getPfbaEnzymes_objective';
    +0101 if size(fixModel.b, 2) == 1
    +0102     fixModel.b = [fixModel.b fixModel.b];
    +0103 end
    +0104 fixModel.b(end+1, :) = [target inf];
    +0105 
    +0106 fixModel.c = zeros(numel(fixModel.rxns), 1);
    +0107 fixModel.c(usageIdx) = -1;
    +0108 
    +0109 solution = solveLP(fixModel);
    +0110 if solution.stat ~= 1
    +0111     error('getPfbaEnzymes: minimising enzyme usage was infeasible at fractionOfOptimum=%g.', fractionOfOptimum)
    +0112 end
    +0113 
    +0114 solution.enzymeUsage    = -solution.f;
    +0115 solution.objectiveValue = model.c' * solution.x;
    +0116 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/flux_analysis/index.html b/doc/src/flux_analysis/index.html new file mode 100644 index 00000000..24f9f67f --- /dev/null +++ b/doc/src/flux_analysis/index.html @@ -0,0 +1,29 @@ + + + + Index for Directory src/flux_analysis + + + + + + + + + + +
    < Master indexIndex for src/flux_analysis >
    + +

    Index for src/flux_analysis

    + +

    Matlab files in this directory:

    + +
     ecFSEOFecFSEOF Run Flux-Scanning with Enforced Objective Function for a target.
     ecFVAecFVA Run flux variability analysis on an ecModel.
     getPfbaEnzymesgetPfbaEnzymes Parsimonious FBA minimising total enzyme usage.
     plotEcFVAplotEcFVA Plot cumulative distribution functions of ecFVA results.
    + + + + +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/flux_analysis/plotEcFVA.html b/doc/src/flux_analysis/plotEcFVA.html new file mode 100644 index 00000000..34fc9ded --- /dev/null +++ b/doc/src/flux_analysis/plotEcFVA.html @@ -0,0 +1,156 @@ + + + + Description of plotEcFVA + + + + + + + + + +
    Home > src > flux_analysis > plotEcFVA.m
    + + + +

    plotEcFVA +

    + +

    PURPOSE ^

    +
    plotEcFVA Plot cumulative distribution functions of ecFVA results.
    + +

    SYNOPSIS ^

    +
    function plotEcFVA(minFlux, maxFlux)
    + +

    DESCRIPTION ^

    +
     plotEcFVA  Plot cumulative distribution functions of ecFVA results.
    +
    + Plots cumulative distribution functions of ecFVA results from one or
    + more ecModel(s) and/or GEM(s).
    +
    + Parameters
    + ----------
    + minFlux : double
    +     vector of minimum flux values, coming from ecFVA. If multiple
    +     ecModels/GEMs are to be visualized, then each column represents a
    +     separate model.
    + maxFlux : double
    +     vector of maximum flux values, matching minFlux.
    +
    + See also
    + --------
    + ecFVA
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function plotEcFVA(minFlux, maxFlux)
    +0002 % plotEcFVA  Plot cumulative distribution functions of ecFVA results.
    +0003 %
    +0004 % Plots cumulative distribution functions of ecFVA results from one or
    +0005 % more ecModel(s) and/or GEM(s).
    +0006 %
    +0007 % Parameters
    +0008 % ----------
    +0009 % minFlux : double
    +0010 %     vector of minimum flux values, coming from ecFVA. If multiple
    +0011 %     ecModels/GEMs are to be visualized, then each column represents a
    +0012 %     separate model.
    +0013 % maxFlux : double
    +0014 %     vector of maximum flux values, matching minFlux.
    +0015 %
    +0016 % See also
    +0017 % --------
    +0018 % ecFVA
    +0019 
    +0020 numMods = size(minFlux,2);
    +0021 fluxRanges = cell(3,1);
    +0022 % Ignore zero flux reactions
    +0023 for i=1:numMods
    +0024     zeroFlux = abs(minFlux(:,i)) < 1e-10 & abs(maxFlux(:,i)) < 1e-10;
    +0025     minFlux(zeroFlux,i) = NaN;
    +0026     maxFlux(zeroFlux,i) = NaN;
    +0027     fluxRange = maxFlux(:,i) - minFlux(:,i);
    +0028     fluxRange(isnan(fluxRange)) = [];
    +0029     fluxRanges{i} = fluxRange;
    +0030 end
    +0031 
    +0032 % Plot all together
    +0033 hold on
    +0034 legendText = cell(1,numel(numMods));
    +0035 for i=1:numMods
    +0036     fluxRange = fluxRanges{i};
    +0037     cdfplot(fluxRange)
    +0038     legendText{i} = (['Model #' num2str(i) ' (median: ' num2str(median(fluxRange,'omitnan')) ')']);
    +0039 end
    +0040 set(gca, 'XScale', 'log', 'Xlim', [1e-7 1e4])
    +0041 set(findall(gca, 'Type', 'Line'), 'LineWidth', 2)
    +0042 legend(legendText,  'Location','northwest')
    +0043 title('Flux variability (cumulative distribution)');
    +0044 xlabel('Variability range (mmol/gDCWh)');
    +0045 ylabel('Cumulative distribution');
    +0046 hold off
    +0047 end
    +0048 
    +0049 function cdfplot(X)
    +0050 % cdfplot(X)
    +0051 % displays a plot of the Empirical Cumulative Distribution Function
    +0052 % (CDF) of the input array X in the current figure. The empirical
    +0053 % CDF y=F(x) is defined as the proportion of X values less than or equal to x.
    +0054 % If input X is a matrix, then cdfplot(X) parses it to the vector and
    +0055 % displays CDF of all values.
    +0056 %
    +0057 % EXAMPLE:
    +0058 % figure;
    +0059 % cdfplot(randn(1,100));
    +0060 % hold on;
    +0061 % cdfplot(-log(1-rand(1,100)));
    +0062 % cdfplot(sqrt(randn(1,100).^2 + randn(1,100).^2))
    +0063 % legend('Normal(0,1) CDF', 'Exponential(1) CDF', 'Rayleigh(1) CDF', 4)
    +0064 
    +0065 % Version 1.0
    +0066 % Alex Podgaetsky, September 2003
    +0067 % alex@wavion.co.il
    +0068 %
    +0069 % Revisions:
    +0070 %       Version 1.0 -   initial version
    +0071 
    +0072 tmp = sort(reshape(X,prod(size(X)),1));
    +0073 Xplot = reshape([tmp tmp].',2*length(tmp),1);
    +0074 
    +0075 tmp = [1:length(X)].'/length(X);
    +0076 Yplot = reshape([tmp tmp].',2*length(tmp),1);
    +0077 Yplot = [0; Yplot(1:(end-1))];
    +0078 
    +0079 figure(gcf);
    +0080 hp = plot(Xplot, Yplot);
    +0081 
    +0082 ColOrd = get(gca, 'ColorOrder'); 
    +0083 ord = mod(length(get(gca,'Children')), size(ColOrd,1)); 
    +0084 set(hp, 'Color', ColOrd((ord==0) + (ord>0)*ord, :));
    +0085 if ~ishold
    +0086      xlabel('X', 'FontWeight','b','FontSize',12);
    +0087      ylabel('F(X)', 'FontWeight','b','FontSize',12);
    +0088      title('Empirical CDF', 'FontWeight','b','FontSize',12);
    +0089      grid on;
    +0090 end
    +0091 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/assignKcatValues.html b/doc/src/gather_kcats/assignKcatValues.html new file mode 100644 index 00000000..a987c42d --- /dev/null +++ b/doc/src/gather_kcats/assignKcatValues.html @@ -0,0 +1,244 @@ + + + + Description of assignKcatValues + + + + + + + + + +
    Home > src > gather_kcats > assignKcatValues.m
    + + + +

    assignKcatValues +

    + +

    PURPOSE ^

    +
    assignKcatValues Select one kcat value per reaction and write to model.ec.
    + +

    SYNOPSIS ^

    +
    function [model, rxnIdx] = assignKcatValues(model,kcatList,varargin)
    + +

    DESCRIPTION ^

    +
     assignKcatValues  Select one kcat value per reaction and write to model.ec.
    +
    + From a kcatList with predicted or suggested kcat values, where each
    + reaction may have multiple entries, one kcat value is selected and written
    + to model.ec.kcat. Zero values are discarded from the start. By default,
    + the maximum value is chosen, but alternatives are available. The kcatList
    + structure is an output of e.g. readDLKcatOutput, readGotEnzymesOutput,
    + readManualKcatList.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    + kcatList : struct
    +     structure array with separate entries for each kcat value, with the
    +     following fields:
    +
    +     - source : e.g. 'DLKcat' or 'gotenzymes'.
    +     - rxns : reaction identifiers, matching model.ec.rxns.
    +     - genes : gene identifiers, matching model.ec.genes.
    +     - substrates : substrate names, matching model.metNames.
    +     - kcats : predicted kcat value in /sec.
    +     - kcatSource : optional, the source of each entry; entries with a zero
    +       kcat are discarded together with their source.
    +
    + Name-Value Arguments
    + --------------------
    + criteria : char
    +     which kcat value should be selected if multiple values are provided.
    +     Options: 'max', 'min', 'median', 'mean' (default 'max'). The written
    +     model.ec.source is taken from the matching entry for 'max'/'min'; for
    +     'median'/'mean', where the selected value need not equal any single
    +     input, it is taken from the first entry instead (arbitrary but
    +     deterministic, since an aggregate has no single "winning" source).
    + overwrite : char
    +     whether existing kcat values should be overwritten. Options: 'true',
    +     'false', 'ifHigher'. The last option will overwrite only if the new
    +     kcat value is higher (default 'true').
    +
    + Returns
    + -------
    + model : struct
    +     ecModel with updated model.ec.kcat and model.ec.source.
    + rxnIdx : double
    +     list of reaction indices (matching model.ec.rxns), to indicate which
    +     kcat values have been changed.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     [model, rxnIdx] = assignKcatValues(model, kcatList);
    +     [model, rxnIdx] = assignKcatValues(model, kcatList, 'criteria', 'mean');
    +
    + See also
    + --------
    + readDLKcatOutput, mergeDLKcatAndFuzzyKcats, applyKcatConstraints
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • collectKcats collectKcats Decide one kcat per reaction from the kcat source files.
    + + + + +

    SOURCE CODE ^

    +
    0001 function [model, rxnIdx] = assignKcatValues(model,kcatList,varargin)
    +0002 % assignKcatValues  Select one kcat value per reaction and write to model.ec.
    +0003 %
    +0004 % From a kcatList with predicted or suggested kcat values, where each
    +0005 % reaction may have multiple entries, one kcat value is selected and written
    +0006 % to model.ec.kcat. Zero values are discarded from the start. By default,
    +0007 % the maximum value is chosen, but alternatives are available. The kcatList
    +0008 % structure is an output of e.g. readDLKcatOutput, readGotEnzymesOutput,
    +0009 % readManualKcatList.
    +0010 %
    +0011 % Parameters
    +0012 % ----------
    +0013 % model : struct
    +0014 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0015 % kcatList : struct
    +0016 %     structure array with separate entries for each kcat value, with the
    +0017 %     following fields:
    +0018 %
    +0019 %     - source : e.g. 'DLKcat' or 'gotenzymes'.
    +0020 %     - rxns : reaction identifiers, matching model.ec.rxns.
    +0021 %     - genes : gene identifiers, matching model.ec.genes.
    +0022 %     - substrates : substrate names, matching model.metNames.
    +0023 %     - kcats : predicted kcat value in /sec.
    +0024 %     - kcatSource : optional, the source of each entry; entries with a zero
    +0025 %       kcat are discarded together with their source.
    +0026 %
    +0027 % Name-Value Arguments
    +0028 % --------------------
    +0029 % criteria : char
    +0030 %     which kcat value should be selected if multiple values are provided.
    +0031 %     Options: 'max', 'min', 'median', 'mean' (default 'max'). The written
    +0032 %     model.ec.source is taken from the matching entry for 'max'/'min'; for
    +0033 %     'median'/'mean', where the selected value need not equal any single
    +0034 %     input, it is taken from the first entry instead (arbitrary but
    +0035 %     deterministic, since an aggregate has no single "winning" source).
    +0036 % overwrite : char
    +0037 %     whether existing kcat values should be overwritten. Options: 'true',
    +0038 %     'false', 'ifHigher'. The last option will overwrite only if the new
    +0039 %     kcat value is higher (default 'true').
    +0040 %
    +0041 % Returns
    +0042 % -------
    +0043 % model : struct
    +0044 %     ecModel with updated model.ec.kcat and model.ec.source.
    +0045 % rxnIdx : double
    +0046 %     list of reaction indices (matching model.ec.rxns), to indicate which
    +0047 %     kcat values have been changed.
    +0048 %
    +0049 % Examples
    +0050 % --------
    +0051 %     % optional arguments may be given positionally or as name-value pairs:
    +0052 %     [model, rxnIdx] = assignKcatValues(model, kcatList);
    +0053 %     [model, rxnIdx] = assignKcatValues(model, kcatList, 'criteria', 'mean');
    +0054 %
    +0055 % See also
    +0056 % --------
    +0057 % readDLKcatOutput, mergeDLKcatAndFuzzyKcats, applyKcatConstraints
    +0058 
    +0059 p = parseGECKOargs(varargin, { ...
    +0060     'criteria',  []; ...
    +0061     'overwrite', []});
    +0062 criteria  = p.criteria;
    +0063 overwrite = p.overwrite;
    +0064 
    +0065 if isempty(overwrite)
    +0066     overwrite = 'true';
    +0067 elseif islogical(overwrite)
    +0068     if overwrite
    +0069         overwrite = 'true';
    +0070     else
    +0071         overwrite = 'false';
    +0072     end
    +0073 end
    +0074 if isempty(criteria)
    +0075     criteria = 'max';
    +0076 end
    +0077 
    +0078 % Remove zero kcat values. Only adjusting fields that are used later.
    +0079 removeZero                      = kcatList.kcats == 0;
    +0080 kcatList.kcats(removeZero)      = [];
    +0081 kcatList.rxns(removeZero)       = [];
    +0082 if isfield(kcatList,'kcatSource')
    +0083     kcatList.kcatSource(removeZero) = [];
    +0084 end
    +0085 
    +0086 % Map to model.ec.rxns
    +0087 [sanityCheck,idxInModel] = ismember(kcatList.rxns,model.ec.rxns);
    +0088 if ~all(sanityCheck)
    +0089     error('Not all reactions in kcatList are found in model.ec.rxns')
    +0090 end
    +0091 % Make vector with single kcat value per reaction
    +0092 idxInModelUnique = unique(idxInModel);
    +0093 selectedKcats    = zeros(numel(idxInModelUnique),1);
    +0094 selectedSource   = cell(numel(selectedKcats),1);
    +0095 if ~isfield(kcatList,'kcatSource')
    +0096     kcatList.kcatSource = cell(numel(kcatList.kcats),1);
    +0097     kcatList.kcatSource(:) = {kcatList.source};
    +0098 end
    +0099 for i=1:numel(idxInModelUnique)
    +0100     ind = idxInModelUnique(i);
    +0101     idxMatch = find(idxInModel == ind);
    +0102     % Choose the maximum number
    +0103     switch criteria
    +0104         case 'max'
    +0105             [selectedKcats(i),j] = max(kcatList.kcats(idxMatch));
    +0106         case 'min'
    +0107             [selectedKcats(i),j] = min(kcatList.kcats(idxMatch));
    +0108         case 'median'
    +0109             selectedKcats(i) = median(kcatList.kcats(idxMatch));
    +0110             j = 1;
    +0111         case 'mean'
    +0112             selectedKcats(i) = mean(kcatList.kcats(idxMatch));
    +0113             j = 1;
    +0114         otherwise
    +0115             error('Invalid criteria specified')
    +0116     end
    +0117     selectedSource(i)    = kcatList.kcatSource(idxMatch(j));
    +0118 end
    +0119 
    +0120 % Populate model.ec.kcat
    +0121 switch overwrite
    +0122     case 'true'
    +0123         model.ec.kcat(idxInModelUnique) = selectedKcats;
    +0124         model.ec.source(idxInModelUnique) = selectedSource;
    +0125     case 'false'
    +0126         emptyKcats = find(model.ec.kcat == 0);
    +0127         [idxInModelUnique,whickKcats] = intersect(idxInModelUnique,emptyKcats,'stable');
    +0128         model.ec.kcat(idxInModelUnique) = selectedKcats(whickKcats);
    +0129         model.ec.source(idxInModelUnique) = selectedSource(whickKcats);
    +0130         
    +0131     case 'ifHigher'
    +0132         higherKcats = model.ec.kcat(idxInModelUnique) < selectedKcats;
    +0133         selectedKcats(~higherKcats) = [];
    +0134         selectedSource(~higherKcats) = [];
    +0135         idxInModelUnique(~higherKcats) = [];
    +0136         model.ec.kcat(idxInModelUnique) = selectedKcats;
    +0137         model.ec.source(idxInModelUnique) = selectedSource;
    +0138     otherwise
    +0139         error('Invalid overwrite flag specified')
    +0140 end
    +0141 rxnIdx = idxInModelUnique;
    +0142 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/assignKcats.html b/doc/src/gather_kcats/assignKcats.html new file mode 100644 index 00000000..8338f833 --- /dev/null +++ b/doc/src/gather_kcats/assignKcats.html @@ -0,0 +1,141 @@ + + + + Description of assignKcats + + + + + + + + + +
    Home > src > gather_kcats > assignKcats.m
    + + + +

    assignKcats +

    + +

    PURPOSE ^

    +
    assignKcats Assign kcats from the kcat source files and apply them.
    + +

    SYNOPSIS ^

    +
    function [model, decisions, report] = assignKcats(model, varargin)
    + +

    DESCRIPTION ^

    +
     assignKcats  Assign kcats from the kcat source files and apply them.
    +
    + Decides one kcat per reaction from the kcat source files in data/kcats,
    + as [kcat_assignment] in model_adapter.toml sets (see collectKcats), writes
    + model.ec.kcat and model.ec.source, and applies the kcat constraints
    + (applyKcatConstraints). Any kcats the model had are replaced: the source
    + files are the input, and nothing in the model is written back to them.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + writeReport : logical
    +     write the decisions to output/<model id>_kcatDecisions.tsv (default
    +     true).
    +
    + Returns
    + -------
    + model : struct
    +     the ecModel with the assigned kcats applied.
    + decisions, report
    +     as returned by collectKcats.
    +
    + Examples
    + --------
    +     updateKcatSources(ecModel);   % gather what the configuration needs
    +     ecModel = assignKcats(ecModel);
    +
    + See also
    + --------
    + collectKcats, updateKcatSources, applyKcatConstraints
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • collectKcats collectKcats Decide one kcat per reaction from the kcat source files.
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [model, decisions, report] = assignKcats(model, varargin)
    +0002 % assignKcats  Assign kcats from the kcat source files and apply them.
    +0003 %
    +0004 % Decides one kcat per reaction from the kcat source files in data/kcats,
    +0005 % as [kcat_assignment] in model_adapter.toml sets (see collectKcats), writes
    +0006 % model.ec.kcat and model.ec.source, and applies the kcat constraints
    +0007 % (applyKcatConstraints). Any kcats the model had are replaced: the source
    +0008 % files are the input, and nothing in the model is written back to them.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % model : struct
    +0013 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0014 %
    +0015 % Name-Value Arguments
    +0016 % --------------------
    +0017 % modelAdapter : ModelAdapter
    +0018 %     a loaded model adapter (default: the current default model adapter).
    +0019 % writeReport : logical
    +0020 %     write the decisions to output/<model id>_kcatDecisions.tsv (default
    +0021 %     true).
    +0022 %
    +0023 % Returns
    +0024 % -------
    +0025 % model : struct
    +0026 %     the ecModel with the assigned kcats applied.
    +0027 % decisions, report
    +0028 %     as returned by collectKcats.
    +0029 %
    +0030 % Examples
    +0031 % --------
    +0032 %     updateKcatSources(ecModel);   % gather what the configuration needs
    +0033 %     ecModel = assignKcats(ecModel);
    +0034 %
    +0035 % See also
    +0036 % --------
    +0037 % collectKcats, updateKcatSources, applyKcatConstraints
    +0038 
    +0039 checkOptions(varargin, {'modelAdapter','writeReport'}, 'assignKcats');
    +0040 [decisions, report, model] = collectKcats(model, varargin{:});
    +0041 model = applyKcatConstraints(model);
    +0042 end
    +0043 
    +0044 function checkOptions(args, names, functionName)
    +0045 % Options are name-value pairs with known names, so a misspelled option is
    +0046 % an error instead of being taken as a positional argument.
    +0047 id = [functionName ':arguments'];
    +0048 given = args(1:2:end);
    +0049 if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given))
    +0050     error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', '))
    +0051 end
    +0052 unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names);
    +0053 if ~isempty(unknown)
    +0054     error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ...
    +0055         strjoin(names, ', '))
    +0056 end
    +0057 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/collectKcats.html b/doc/src/gather_kcats/collectKcats.html new file mode 100644 index 00000000..1ef11037 --- /dev/null +++ b/doc/src/gather_kcats/collectKcats.html @@ -0,0 +1,628 @@ + + + + Description of collectKcats + + + + + + + + + +
    Home > src > gather_kcats > collectKcats.m
    + + + +

    collectKcats +

    + +

    PURPOSE ^

    +
    collectKcats Decide one kcat per reaction from the kcat source files.
    + +

    SYNOPSIS ^

    +
    function [decisions, report, ecModel] = collectKcats(model, varargin)
    + +

    DESCRIPTION ^

    +
     collectKcats  Decide one kcat per reaction from the kcat source files.
    +
    + Combines the kcat source files in data/kcats (see kcatsFromBrenda,
    + kcatsFromDLKcat, kcatsFromOKP and saveKcatSource) as [kcat_assignment] in
    + model_adapter.toml sets, without changing the model given. assignKcats
    + applies the decisions.
    +
    + The order is a preset or a list of stages:
    +
    +     [kcat_assignment]
    +     preset = "brenda_ec_tree"    # the default; or ec_tree_homologs, ec_tree_okp, okp,
    +                                  # gecko_median, gecko_classic
    +     isozymes = true              # fill from isozymes after the stages
    +     standard = true              # standard kcat for the rest
    +
    +     # instead of a preset:
    +     [[kcat_assignment.stage]]
    +     action = "select"            # or "combine"
    +     sources = ["custom", "database_top", "ec_tree"]
    +     criteria = "max"             # select: among several values of one source
    +     top_origin_limit = 1
    +
    +     [kcat_sources.okp]
    +     methods = ["CataPro", "UniKP"]   # the okp source group
    +
    + A stage decides the reactions that are still open:
    + - select: the first listed source with a value (see mergeKcats). Sources
    +   are the names of source files (custom, ec_tree, dlkcat, okp_catapro,
    +   ...) and the BRENDA quality tiers database_exact, database_top and
    +   database_bottom, which read brenda.tsv.
    + - combine: all listed sources with a value, each corrected for its bias
    +   and weighted by 1 / its error variance, both for the source's evidence
    +   for that reaction (the EC tree: measurements of the EC and its EC
    +   level; an OKP method: the enzyme's similarity to the method's training
    +   sequences). The parameters come with the BRENDA files
    +   (kcatCombineParams.tsv). model.ec.source reads 'combined (sd=<log10
    +   sd>, n=<sources>)'; sd is the uncertainty for a new measurement.
    + In both, okp stands for the OKP methods of [kcat_sources.okp] methods
    + (default: all methods with combination parameters).
    +
    + The presets:
    + - brenda_ec_tree (the default): custom kcats, the BRENDA median of
    +   measurements of the organism on the reaction's substrate (origin 1,
    +   without EC wildcards), the EC tree (kcatsFromECTree); then the OKP
    +   methods combined for the reactions left (without an EC number).
    + - ec_tree_homologs: custom kcats, the organism's own BRENDA value; then
    +   the EC tree and homologs (kcatsFromHomologs) combined; then the OKP
    +   methods combined.
    + - ec_tree_okp: custom kcats, the organism's own BRENDA value; then the EC
    +   tree, homologs and the OKP methods combined; then the OKP methods
    +   combined.
    + - okp: custom kcats; then the OKP methods combined.
    + - gecko_median: custom kcats, the BRENDA median of matches without EC
    +   wildcards from the organism or other organisms, with or without the
    +   substrate (origin 1 to 4), DLKcat, then the other BRENDA matches (EC
    +   wildcards, and specific activities, origin 5 and 6).
    + - gecko_classic: as gecko_median with the BRENDA maximum and the
    +   specific-activity matches above DLKcat (origin up to 6), as the GECKO 3
    +   tutorial.
    + Against measured kcats hidden from the search, the EC tree was closer
    + than the BRENDA median at origins 2 and 4 and with EC wildcards and as
    + close at origins 1 and 3; the EC tree combined with the OKP methods was
    + slightly closer than the EC tree, and the OKP methods combined as close.
    + In ecModels, values combined with predictions set high-turnover enzymes
    + such as ATP synthase too low, which is why the default uses predictions
    + only where there is no value from measurements. The BRENDA aggregation is
    + [kcat_sources.brenda] aggregation (see updateKcatSources).
    +
    + After the stages:
    + - custom kcats of data/customKcats.tsv are applied (applyCustomKcats),
    +   when a stage lists custom but there is no data/kcats/custom.tsv;
    + - with isozymes, reactions without a kcat take one from their isozymes
    +   (getKcatAcrossIsozymes);
    + - with standard, the remaining reactions get the standard kcat
    +   (getStandardKcat).
    +
    + A source file a stage names that does not exist is reported and left out.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + writeReport : logical
    +     write the decisions to output/<model id>_kcatDecisions.tsv (default
    +     true).
    +
    + Returns
    + -------
    + decisions : table
    +     one row per model.ec reaction: ecRxn, stage (the stage number, or
    +     custom, isozymes, standard, or empty when no kcat was found), source
    +     (as in model.ec.source), kcat, candidates (the number of values the
    +     deciding source had for the reaction, or of sources combined),
    +     spreadLog10 (their range, in log10 units) and sdLog10 (the
    +     uncertainty of a combined value).
    + report : struct
    +     - preset: the preset used, or '' with stages;
    +     - missing: source files the stages name that do not exist;
    +     - sources: per source file loaded, its unmatched, partial and invalid
    +       rows (see loadKcatSource).
    + ecModel : struct
    +     the model with the decided kcats, before applyKcatConstraints; this
    +     is what assignKcats returns, after applying the constraints.
    +
    + Examples
    + --------
    +     decisions = collectKcats(ecModel);
    +     decisions(strcmp(decisions.stage, ''), :)   % reactions without a kcat
    +
    + See also
    + --------
    + assignKcats, updateKcatSources, loadKcatSource, mergeKcats, assignKcatValues
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • assignKcatValues assignKcatValues Select one kcat value per reaction and write to model.ec.
    • getStandardKcat getStandardKcat Assign standard kcat and MW to reactions without enzymes.
    • kcatAssignmentConfig kcatAssignmentConfig The kcat assignment settings of a model adapter.
    • loadKcatSource loadKcatSource Read a kcat source file and map its rows to an ecModel.
    • mergeKcats mergeKcats Merge any number of kcatLists, keeping the highest-priority
    +This function is called by: +
      +
    • assignKcats assignKcats Assign kcats from the kcat source files and apply them.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [decisions, report, ecModel] = collectKcats(model, varargin)
    +0002 % collectKcats  Decide one kcat per reaction from the kcat source files.
    +0003 %
    +0004 % Combines the kcat source files in data/kcats (see kcatsFromBrenda,
    +0005 % kcatsFromDLKcat, kcatsFromOKP and saveKcatSource) as [kcat_assignment] in
    +0006 % model_adapter.toml sets, without changing the model given. assignKcats
    +0007 % applies the decisions.
    +0008 %
    +0009 % The order is a preset or a list of stages:
    +0010 %
    +0011 %     [kcat_assignment]
    +0012 %     preset = "brenda_ec_tree"    # the default; or ec_tree_homologs, ec_tree_okp, okp,
    +0013 %                                  # gecko_median, gecko_classic
    +0014 %     isozymes = true              # fill from isozymes after the stages
    +0015 %     standard = true              # standard kcat for the rest
    +0016 %
    +0017 %     # instead of a preset:
    +0018 %     [[kcat_assignment.stage]]
    +0019 %     action = "select"            # or "combine"
    +0020 %     sources = ["custom", "database_top", "ec_tree"]
    +0021 %     criteria = "max"             # select: among several values of one source
    +0022 %     top_origin_limit = 1
    +0023 %
    +0024 %     [kcat_sources.okp]
    +0025 %     methods = ["CataPro", "UniKP"]   # the okp source group
    +0026 %
    +0027 % A stage decides the reactions that are still open:
    +0028 % - select: the first listed source with a value (see mergeKcats). Sources
    +0029 %   are the names of source files (custom, ec_tree, dlkcat, okp_catapro,
    +0030 %   ...) and the BRENDA quality tiers database_exact, database_top and
    +0031 %   database_bottom, which read brenda.tsv.
    +0032 % - combine: all listed sources with a value, each corrected for its bias
    +0033 %   and weighted by 1 / its error variance, both for the source's evidence
    +0034 %   for that reaction (the EC tree: measurements of the EC and its EC
    +0035 %   level; an OKP method: the enzyme's similarity to the method's training
    +0036 %   sequences). The parameters come with the BRENDA files
    +0037 %   (kcatCombineParams.tsv). model.ec.source reads 'combined (sd=<log10
    +0038 %   sd>, n=<sources>)'; sd is the uncertainty for a new measurement.
    +0039 % In both, okp stands for the OKP methods of [kcat_sources.okp] methods
    +0040 % (default: all methods with combination parameters).
    +0041 %
    +0042 % The presets:
    +0043 % - brenda_ec_tree (the default): custom kcats, the BRENDA median of
    +0044 %   measurements of the organism on the reaction's substrate (origin 1,
    +0045 %   without EC wildcards), the EC tree (kcatsFromECTree); then the OKP
    +0046 %   methods combined for the reactions left (without an EC number).
    +0047 % - ec_tree_homologs: custom kcats, the organism's own BRENDA value; then
    +0048 %   the EC tree and homologs (kcatsFromHomologs) combined; then the OKP
    +0049 %   methods combined.
    +0050 % - ec_tree_okp: custom kcats, the organism's own BRENDA value; then the EC
    +0051 %   tree, homologs and the OKP methods combined; then the OKP methods
    +0052 %   combined.
    +0053 % - okp: custom kcats; then the OKP methods combined.
    +0054 % - gecko_median: custom kcats, the BRENDA median of matches without EC
    +0055 %   wildcards from the organism or other organisms, with or without the
    +0056 %   substrate (origin 1 to 4), DLKcat, then the other BRENDA matches (EC
    +0057 %   wildcards, and specific activities, origin 5 and 6).
    +0058 % - gecko_classic: as gecko_median with the BRENDA maximum and the
    +0059 %   specific-activity matches above DLKcat (origin up to 6), as the GECKO 3
    +0060 %   tutorial.
    +0061 % Against measured kcats hidden from the search, the EC tree was closer
    +0062 % than the BRENDA median at origins 2 and 4 and with EC wildcards and as
    +0063 % close at origins 1 and 3; the EC tree combined with the OKP methods was
    +0064 % slightly closer than the EC tree, and the OKP methods combined as close.
    +0065 % In ecModels, values combined with predictions set high-turnover enzymes
    +0066 % such as ATP synthase too low, which is why the default uses predictions
    +0067 % only where there is no value from measurements. The BRENDA aggregation is
    +0068 % [kcat_sources.brenda] aggregation (see updateKcatSources).
    +0069 %
    +0070 % After the stages:
    +0071 % - custom kcats of data/customKcats.tsv are applied (applyCustomKcats),
    +0072 %   when a stage lists custom but there is no data/kcats/custom.tsv;
    +0073 % - with isozymes, reactions without a kcat take one from their isozymes
    +0074 %   (getKcatAcrossIsozymes);
    +0075 % - with standard, the remaining reactions get the standard kcat
    +0076 %   (getStandardKcat).
    +0077 %
    +0078 % A source file a stage names that does not exist is reported and left out.
    +0079 %
    +0080 % Parameters
    +0081 % ----------
    +0082 % model : struct
    +0083 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0084 %
    +0085 % Name-Value Arguments
    +0086 % --------------------
    +0087 % modelAdapter : ModelAdapter
    +0088 %     a loaded model adapter (default: the current default model adapter).
    +0089 % writeReport : logical
    +0090 %     write the decisions to output/<model id>_kcatDecisions.tsv (default
    +0091 %     true).
    +0092 %
    +0093 % Returns
    +0094 % -------
    +0095 % decisions : table
    +0096 %     one row per model.ec reaction: ecRxn, stage (the stage number, or
    +0097 %     custom, isozymes, standard, or empty when no kcat was found), source
    +0098 %     (as in model.ec.source), kcat, candidates (the number of values the
    +0099 %     deciding source had for the reaction, or of sources combined),
    +0100 %     spreadLog10 (their range, in log10 units) and sdLog10 (the
    +0101 %     uncertainty of a combined value).
    +0102 % report : struct
    +0103 %     - preset: the preset used, or '' with stages;
    +0104 %     - missing: source files the stages name that do not exist;
    +0105 %     - sources: per source file loaded, its unmatched, partial and invalid
    +0106 %       rows (see loadKcatSource).
    +0107 % ecModel : struct
    +0108 %     the model with the decided kcats, before applyKcatConstraints; this
    +0109 %     is what assignKcats returns, after applying the constraints.
    +0110 %
    +0111 % Examples
    +0112 % --------
    +0113 %     decisions = collectKcats(ecModel);
    +0114 %     decisions(strcmp(decisions.stage, ''), :)   % reactions without a kcat
    +0115 %
    +0116 % See also
    +0117 % --------
    +0118 % assignKcats, updateKcatSources, loadKcatSource, mergeKcats, assignKcatValues
    +0119 
    +0120 checkOptions(varargin, {'modelAdapter','writeReport'}, 'collectKcats');
    +0121 p = parseGECKOargs(varargin, {'modelAdapter', []; 'writeReport', true});
    +0122 modelAdapter = p.modelAdapter;
    +0123 if isempty(modelAdapter)
    +0124     modelAdapter = ModelAdapterManager.getDefault();
    +0125     if isempty(modelAdapter)
    +0126         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0127     end
    +0128 end
    +0129 params = modelAdapter.params;
    +0130 config = kcatAssignmentConfig(params);
    +0131 kcatDir = fullfile(params.path, 'data', 'kcats');
    +0132 
    +0133 ecModel = model;
    +0134 nEc = numel(ecModel.ec.rxns);
    +0135 ecModel.ec.kcat(:) = 0;
    +0136 ecModel.ec.source(:) = {''};
    +0137 stage = repmat({''}, nEc, 1);
    +0138 candidates = zeros(nEc, 1);
    +0139 spread = nan(nEc, 1);
    +0140 sd = nan(nEc, 1);
    +0141 combineParams = [];
    +0142 
    +0143 report.preset = config.preset;
    +0144 report.missing = {};
    +0145 report.sources = struct();
    +0146 loaded = struct();
    +0147 legacyCustom = false;
    +0148 
    +0149     function list = loadSource(name)
    +0150         % The kcat list of a source file, or [] when it does not exist.
    +0151         list = [];
    +0152         file = fullfile(kcatDir, [name '.tsv']);
    +0153         if isfile(file)
    +0154             [list, rep] = loadKcatSource(ecModel, file);
    +0155             report.sources.(name) = rep;
    +0156         elseif strcmp(name, 'custom') && isfile(fullfile(params.path, 'data', 'customKcats.tsv'))
    +0157             legacyCustom = true;
    +0158         else
    +0159             report.missing{end+1} = name;
    +0160             printOrange(sprintf(['No kcat source file %s; it is left out. ' ...
    +0161                 'updateKcatSources gathers it.\n'], file));
    +0162         end
    +0163     end
    +0164 
    +0165 for s = 1:numel(config.stages)
    +0166     st = config.stages(s);
    +0167     if strcmp(st.action, 'combine')
    +0168         names = {};
    +0169         lists = {};
    +0170         for t = 1:numel(st.files)
    +0171             name = st.files{t};
    +0172             if ~isfield(loaded, name)
    +0173                 loaded.(name) = loadSource(name);
    +0174             end
    +0175             if ~isempty(loaded.(name))
    +0176                 names{end+1} = name; %#ok<AGROW>
    +0177                 lists{end+1} = loaded.(name); %#ok<AGROW>
    +0178             end
    +0179         end
    +0180         if isempty(names)
    +0181             continue
    +0182         end
    +0183         if isempty(combineParams)
    +0184             combineParams = loadCombineParams(modelAdapter);
    +0185         end
    +0186         openRxns = ecModel.ec.rxns(ecModel.ec.kcat == 0);
    +0187         c = combineKcats(names, lists, openRxns, combineParams);
    +0188         if isempty(c.rxns)
    +0189             continue
    +0190         end
    +0191         [~, idx] = ismember(c.rxns, ecModel.ec.rxns);
    +0192         ecModel.ec.kcat(idx) = c.kcats;
    +0193         ecModel.ec.source(idx) = cellstr(compose('combined (sd=%.2f, n=%d)', c.sd, c.n));
    +0194         stage(idx) = {sprintf('%d', s)};
    +0195         candidates(idx) = c.n;
    +0196         spread(idx) = c.spread;
    +0197         sd(idx) = c.sd;
    +0198         continue
    +0199     end
    +0200     lists = {};
    +0201     priority = {};
    +0202     for t = 1:numel(st.files)
    +0203         token = st.files{t};
    +0204         name = sourceFile(token);
    +0205         if ~isfield(loaded, name)
    +0206             loaded.(name) = loadSource(name);
    +0207         end
    +0208         list = loaded.(name);
    +0209         if isempty(list)
    +0210             continue
    +0211         end
    +0212         if ~any(cellfun(@(l) isequal(l, list), lists))
    +0213             lists{end+1} = list; %#ok<AGROW>
    +0214         end
    +0215         if startsWith(token, 'database_')
    +0216             priority{end+1} = token; %#ok<AGROW>
    +0217         else
    +0218             % The labels of the file's rows, at the file's place in the order.
    +0219             labels = unique(cellfun(@normalizeSource, list.kcatSource, 'UniformOutput', false), 'stable');
    +0220             priority = [priority, labels(~ismember(labels, {'brenda','sabio_rk'}))']; %#ok<AGROW>
    +0221         end
    +0222     end
    +0223     if isempty(lists) || isempty(priority)
    +0224         continue
    +0225     end
    +0226     merged = mergeKcats(lists, priority, 'topOriginLimit', st.topOriginLimit, ...
    +0227         'bottomOriginLimit', st.bottomOriginLimit, 'wildcardLimit', st.wildcardLimit);
    +0228     if isempty(merged.rxns)
    +0229         continue
    +0230     end
    +0231     open = ecModel.ec.kcat == 0;
    +0232     [ecModel, idx] = assignKcatValues(ecModel, merged, 'criteria', st.criteria, 'overwrite', 'false');
    +0233     idx = idx(open(idx));
    +0234     stage(idx) = {sprintf('%d', s)};
    +0235     [~, where] = ismember(merged.rxns, ecModel.ec.rxns);
    +0236     valid = merged.kcats > 0;
    +0237     for i = idx(:)'
    +0238         values = merged.kcats(where == i & valid);
    +0239         candidates(i) = numel(values);
    +0240         spread(i) = log10(max(values)) - log10(min(values));
    +0241     end
    +0242 end
    +0243 
    +0244 if legacyCustom
    +0245     before = ecModel.ec.kcat;
    +0246     ecModel = applyCustomKcats(ecModel, 'modelAdapter', modelAdapter);
    +0247     changed = ecModel.ec.kcat ~= before;
    +0248     stage(changed) = {'custom'};
    +0249     candidates(changed) = 1;
    +0250     spread(changed) = 0;
    +0251 end
    +0252 if config.isozymes && ~ecModel.ec.geckoLight
    +0253     before = ecModel.ec.kcat == 0;
    +0254     ecModel = getKcatAcrossIsozymes(ecModel);
    +0255     stage(before & ecModel.ec.kcat > 0) = {'isozymes'};
    +0256 end
    +0257 if config.standard
    +0258     ecModel = getStandardKcat(ecModel, 'modelAdapter', modelAdapter);
    +0259     n = numel(ecModel.ec.rxns);
    +0260     stage(end+1:n) = {''};
    +0261     candidates(end+1:n) = 0;
    +0262     spread(end+1:n) = NaN;
    +0263     sd(end+1:n) = NaN;
    +0264     stage(strcmp(ecModel.ec.source, 'standard') & ecModel.ec.kcat > 0) = {'standard'};
    +0265 end
    +0266 
    +0267 decisions = table(ecModel.ec.rxns(:), stage(:), ecModel.ec.source(:), ecModel.ec.kcat(:), ...
    +0268     candidates(:), spread(:), sd(:), 'VariableNames', {'ecRxn','stage','source','kcat','candidates', ...
    +0269     'spreadLog10','sdLog10'});
    +0270 if p.writeReport
    +0271     outDir = fullfile(params.path, 'output');
    +0272     if ~isfolder(outDir)
    +0273         mkdir(outDir);
    +0274     end
    +0275     id = 'ecModel';
    +0276     if isfield(model, 'id') && ~isempty(model.id)
    +0277         id = char(model.id);
    +0278     end
    +0279     writetable(decisions, fullfile(outDir, [id '_kcatDecisions.tsv']), 'FileType', 'text', ...
    +0280         'Delimiter', '\t');
    +0281 end
    +0282 nOpen = sum(strcmp(stage, ''));
    +0283 fprintf('Kcats decided for %d of %d reactions.\n', numel(stage) - nOpen, numel(stage));
    +0284 end
    +0285 
    +0286 function s = normalizeSource(label)
    +0287 % As mergeKcats folds source labels: lower case, other characters as '_'.
    +0288 s = lower(strtrim(char(label)));
    +0289 s = regexprep(s, '[^0-9a-z]+', '_');
    +0290 s = regexprep(s, '^_+|_+$', '');
    +0291 end
    +0292 
    +0293 function name = sourceFile(token)
    +0294 % The source file a stage token reads: the BRENDA tiers read brenda.tsv.
    +0295 if startsWith(token, 'database_')
    +0296     name = 'brenda';
    +0297 else
    +0298     name = token;
    +0299 end
    +0300 end
    +0301 
    +0302 function checkOptions(args, names, functionName)
    +0303 % Options are name-value pairs with known names, so a misspelled option is
    +0304 % an error instead of being taken as a positional argument.
    +0305 id = [functionName ':arguments'];
    +0306 given = args(1:2:end);
    +0307 if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given))
    +0308     error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', '))
    +0309 end
    +0310 unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names);
    +0311 if ~isempty(unknown)
    +0312     error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ...
    +0313         strjoin(names, ', '))
    +0314 end
    +0315 end
    +0316 
    +0317 function params = loadCombineParams(modelAdapter)
    +0318 % kcatCombineParams.tsv of the BRENDA folder, or of GECKO's BRENDA release.
    +0319 file = fullfile(modelAdapter.getBrendaDBFolder(), 'kcatCombineParams.tsv');
    +0320 if ~isfile(file)
    +0321     file = fullfile(fetchBrendaAsset({'kcatCombineParams.tsv'}), 'kcatCombineParams.tsv');
    +0322 end
    +0323 lines = strsplit(fileread(file), {'\r\n', '\n'});
    +0324 params.measurementSd = 0.48;
    +0325 params.minVariance = 0.01;
    +0326 params.scaleKeys = {};
    +0327 params.scales = [];
    +0328 k = 1;
    +0329 while k <= numel(lines) && startsWith(lines{k}, '#')
    +0330     tok = regexp(lines{k}, '^#\s*([^:]+):\s*(.*)$', 'tokens', 'once');
    +0331     if ~isempty(tok)
    +0332         key = strtrim(tok{1});
    +0333         value = str2double(strtrim(tok{2}));
    +0334         if strcmp(key, 'measurement_sd')
    +0335             params.measurementSd = value;
    +0336         elseif strcmp(key, 'min_variance')
    +0337             params.minVariance = value;
    +0338         elseif startsWith(key, 'interval_scale ')
    +0339             params.scaleKeys{end+1} = key(numel('interval_scale ')+1:end);
    +0340             params.scales(end+1) = value;
    +0341         end
    +0342     end
    +0343     k = k + 1;
    +0344 end
    +0345 header = strsplit(lines{k}, '\t');
    +0346 rows = lines(k+1:end);
    +0347 rows = rows(~cellfun(@isempty, strtrim(rows)));
    +0348 fields = cellfun(@(r) strsplit(r, '\t', 'CollapseDelimiters', false), rows, 'UniformOutput', false);
    +0349 fields = vertcat(fields{:});
    +0350 col = @(name) fields(:, strcmp(header, name));
    +0351 params.source = col('source');
    +0352 params.bin = col('bin');
    +0353 params.bias = str2double(col('bias'));
    +0354 params.variance = str2double(col('variance'));
    +0355 end
    +0356 
    +0357 function c = combineKcats(names, lists, openRxns, params)
    +0358 % One kcat per reaction from several sources: each source's value corrected
    +0359 % for its bias and weighted by 1 / its error variance, both for the
    +0360 % source's evidence bin (see evidenceBin). Several rows of one source for a
    +0361 % reaction give their median, with the bin of best evidence; a value
    +0362 % without a known bin gets the source's largest variance. geckopy's
    +0363 % combine_kcats does the same.
    +0364 unknown = setdiff(names, params.source);
    +0365 if ~isempty(unknown)
    +0366     error('collectKcats:combine', 'No combination parameters for %s; known sources: %s.', ...
    +0367         strjoin(unknown, ', '), strjoin(unique(params.source), ', '))
    +0368 end
    +0369 R = {}; S = {}; X = []; W = []; V = [];
    +0370 for k = 1:numel(names)
    +0371     name = names{k};
    +0372     list = lists{k};
    +0373     keep = ismember(list.rxns, openRxns) & list.kcats > 0 & isfinite(list.kcats);
    +0374     rxns = list.rxns(keep);
    +0375     values = log10(list.kcats(keep));
    +0376     details = list.detail(keep);
    +0377     mine = strcmp(params.source, name);
    +0378     srcBins = params.bin(mine);
    +0379     srcBias = params.bias(mine);
    +0380     srcVar = params.variance(mine);
    +0381     [~, worst] = max(srcVar);
    +0382     [u, ~, g] = unique(rxns, 'stable');
    +0383     for r = 1:numel(u)
    +0384         rows = find(g == r);
    +0385         bins = cellfun(@(d) evidenceBin(name, d), details(rows), 'UniformOutput', false);
    +0386         [found, where] = ismember(bins, srcBins);
    +0387         if any(found)
    +0388             [~, best] = min(srcVar(where(found)));
    +0389             pick = where(found);
    +0390             pick = pick(best);
    +0391         else
    +0392             pick = worst;
    +0393         end
    +0394         R{end+1, 1} = u{r}; %#ok<AGROW>
    +0395         S{end+1, 1} = name; %#ok<AGROW>
    +0396         V(end+1, 1) = median(values(rows)); %#ok<AGROW>
    +0397         X(end+1, 1) = median(values(rows)) - srcBias(pick); %#ok<AGROW>
    +0398         W(end+1, 1) = 1 / max(srcVar(pick), params.minVariance); %#ok<AGROW>
    +0399     end
    +0400 end
    +0401 [u, ~, g] = unique(R, 'stable');
    +0402 c.rxns = u;
    +0403 n = numel(u);
    +0404 c.kcats = zeros(n, 1); c.sd = zeros(n, 1); c.n = zeros(n, 1); c.spread = zeros(n, 1);
    +0405 for r = 1:n
    +0406     rows = g == r;
    +0407     w = W(rows);
    +0408     c.kcats(r) = 10 ^ (sum(w .* X(rows)) / sum(w));
    +0409     srcs = S(rows);
    +0410     hasOkp = any(startsWith(srcs, 'okp_'));
    +0411     hasTree = any(strcmp(srcs, 'ec_tree'));
    +0412     if hasTree && hasOkp
    +0413         key = 'ec_tree+okp';
    +0414     elseif hasOkp
    +0415         key = 'okp';
    +0416     elseif hasTree
    +0417         key = 'ec_tree+homologs';
    +0418     else
    +0419         key = '';
    +0420     end
    +0421     scale = 1;
    +0422     hit = strcmp(params.scaleKeys, key);
    +0423     if any(hit)
    +0424         scale = params.scales(find(hit, 1));
    +0425     end
    +0426     c.sd(r) = sqrt(1 / sum(w) + params.measurementSd ^ 2) * scale;
    +0427     c.n(r) = sum(rows);
    +0428     c.spread(r) = max(V(rows)) - min(V(rows));
    +0429 end
    +0430 end
    +0431 
    +0432 function b = evidenceBin(source, detail)
    +0433 % The evidence bin of a source's value, from its detail column.
    +0434 b = '';
    +0435 if strcmp(source, 'ec_tree')
    +0436     n = regexp(detail, 'n=(\d+)', 'tokens', 'once');
    +0437     depth = regexp(detail, 'depth=(\d)', 'tokens', 'once');
    +0438     if ~isempty(depth) && strcmp(depth{1}, '4') && ~isempty(n)
    +0439         v = str2double(n{1});
    +0440         edges = [2 5 20 100];
    +0441         labels = {'1-2', '3-5', '6-20', '21-100', '>100'};
    +0442         b = ['ec4:' labels{find([v <= edges, true], 1)}];
    +0443     elseif ~isempty(depth)
    +0444         b = ['ec' depth{1}];
    +0445     else
    +0446         b = 'ec0';
    +0447     end
    +0448 elseif strcmp(source, 'homologs')
    +0449     t = regexp(detail, 'identity=([\d.]+)', 'tokens', 'once');
    +0450     if ~isempty(t) && str2double(t{1}) >= 0.95
    +0451         b = 'exact'; % the same protein: an assumed bin, see kcatCombineParams.tsv
    +0452     elseif ~isempty(t)
    +0453         labels = {'40', '50', '60', '70', '80', '90'};
    +0454         b = labels{find([str2double(t{1}) <= [0.5 0.6 0.7 0.8 0.9], true], 1)};
    +0455     end
    +0456 elseif startsWith(source, 'okp_')
    +0457     t = regexp(detail, 'similarity=([\d.]+)', 'tokens', 'once');
    +0458     if ~isempty(t)
    +0459         labels = {'<40', '40-60', '60-80', '>80'};
    +0460         b = labels{find([str2double(t{1}) <= [40 60 80], true], 1)};
    +0461     end
    +0462 end
    +0463 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/convertCustomKcats.html b/doc/src/gather_kcats/convertCustomKcats.html new file mode 100644 index 00000000..8d6b2950 --- /dev/null +++ b/doc/src/gather_kcats/convertCustomKcats.html @@ -0,0 +1,233 @@ + + + + Description of convertCustomKcats + + + + + + + + + +
    Home > src > gather_kcats > convertCustomKcats.m
    + + + +

    convertCustomKcats +

    + +

    PURPOSE ^

    +
    convertCustomKcats Convert data/customKcats.tsv into data/kcats/custom.tsv.
    + +

    SYNOPSIS ^

    +
    function [file, report] = convertCustomKcats(model, varargin)
    + +

    DESCRIPTION ^

    +
     convertCustomKcats  Convert data/customKcats.tsv into data/kcats/custom.tsv.
    +
    + Writes the custom kcats of a GECKO 3 project as the curated kcat source
    + file data/kcats/custom.tsv, which collectKcats reads first. The kcats are
    + those applyCustomKcats gives the ecModel, including which of two entries
    + for the same reaction wins: one row per reaction, keyed by conventional
    + reaction and enzyme set (see getEcRxnKeys), with the entry's notes in the
    + note column. The stoicho column is left out: complex stoichiometry comes
    + from applyComplexData. Unlike applyCustomKcats, custom.tsv also applies to
    + light ecModels. geckopy has the same (convert_custom_kcats).
    +
    + Parameters
    + ----------
    + model : struct
    +     the full ecModel the custom kcats are for (with EC data).
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + customKcats : char
    +     the file to convert (default: data/customKcats.tsv in the project).
    + outFile : char
    +     the file to write (default: data/kcats/custom.tsv in the project). An
    +     existing file is not overwritten.
    +
    + Returns
    + -------
    + file : char
    +     the file written.
    + report : struct
    +     - rows: number of rows written;
    +     - partial: reactions whose enzymes only partly match an entry, which
    +       applyCustomKcats does not change either (its notMatch).
    +
    + Examples
    + --------
    +     convertCustomKcats(ecModel);   % then collectKcats/assignKcats read custom.tsv
    +
    + See also
    + --------
    + collectKcats, applyCustomKcats, getEcRxnKeys, upgradeGECKOproject
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • getEcRxnKeys getEcRxnKeys Build-independent keys of the model.ec reactions.
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [file, report] = convertCustomKcats(model, varargin)
    +0002 % convertCustomKcats  Convert data/customKcats.tsv into data/kcats/custom.tsv.
    +0003 %
    +0004 % Writes the custom kcats of a GECKO 3 project as the curated kcat source
    +0005 % file data/kcats/custom.tsv, which collectKcats reads first. The kcats are
    +0006 % those applyCustomKcats gives the ecModel, including which of two entries
    +0007 % for the same reaction wins: one row per reaction, keyed by conventional
    +0008 % reaction and enzyme set (see getEcRxnKeys), with the entry's notes in the
    +0009 % note column. The stoicho column is left out: complex stoichiometry comes
    +0010 % from applyComplexData. Unlike applyCustomKcats, custom.tsv also applies to
    +0011 % light ecModels. geckopy has the same (convert_custom_kcats).
    +0012 %
    +0013 % Parameters
    +0014 % ----------
    +0015 % model : struct
    +0016 %     the full ecModel the custom kcats are for (with EC data).
    +0017 %
    +0018 % Name-Value Arguments
    +0019 % --------------------
    +0020 % modelAdapter : ModelAdapter
    +0021 %     a loaded model adapter (default: the current default model adapter).
    +0022 % customKcats : char
    +0023 %     the file to convert (default: data/customKcats.tsv in the project).
    +0024 % outFile : char
    +0025 %     the file to write (default: data/kcats/custom.tsv in the project). An
    +0026 %     existing file is not overwritten.
    +0027 %
    +0028 % Returns
    +0029 % -------
    +0030 % file : char
    +0031 %     the file written.
    +0032 % report : struct
    +0033 %     - rows: number of rows written;
    +0034 %     - partial: reactions whose enzymes only partly match an entry, which
    +0035 %       applyCustomKcats does not change either (its notMatch).
    +0036 %
    +0037 % Examples
    +0038 % --------
    +0039 %     convertCustomKcats(ecModel);   % then collectKcats/assignKcats read custom.tsv
    +0040 %
    +0041 % See also
    +0042 % --------
    +0043 % collectKcats, applyCustomKcats, getEcRxnKeys, upgradeGECKOproject
    +0044 
    +0045 checkOptions(varargin, {'modelAdapter','customKcats','outFile'}, 'convertCustomKcats');
    +0046 p = parseGECKOargs(varargin, {'modelAdapter', []; 'customKcats', []; 'outFile', []});
    +0047 modelAdapter = p.modelAdapter;
    +0048 if isempty(modelAdapter)
    +0049     modelAdapter = ModelAdapterManager.getDefault();
    +0050     if isempty(modelAdapter)
    +0051         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0052     end
    +0053 end
    +0054 if model.ec.geckoLight
    +0055     error('convertCustomKcats:light', ['applyCustomKcats does not work on light ecModels; give ' ...
    +0056         'the full ecModel. The custom.tsv written applies to light ecModels too.'])
    +0057 end
    +0058 inFile = p.customKcats;
    +0059 if isempty(inFile)
    +0060     inFile = fullfile(modelAdapter.params.path, 'data', 'customKcats.tsv');
    +0061 end
    +0062 file = p.outFile;
    +0063 if isempty(file)
    +0064     file = fullfile(modelAdapter.params.path, 'data', 'kcats', 'custom.tsv');
    +0065 end
    +0066 if ~isfile(inFile)
    +0067     error('convertCustomKcats:missing', 'No custom kcats file %s.', inFile)
    +0068 end
    +0069 if isfile(file)
    +0070     error('convertCustomKcats:exists', '%s exists and is not overwritten.', file)
    +0071 end
    +0072 
    +0073 base = model;
    +0074 base.ec.notes(:) = {''};
    +0075 [applied, rxnUpdated, notMatch] = applyCustomKcats(base, 'customKcats', inFile, 'modelAdapter', modelAdapter);
    +0076 idx = find(ismember(applied.ec.rxns, rxnUpdated));
    +0077 [baseRxns, enzymeSets] = getEcRxnKeys(applied);
    +0078 rows = strings(numel(idx), 9);
    +0079 for k = 1:numel(idx)
    +0080     i = idx(k);
    +0081     note = regexprep(applied.ec.notes{i}, '[\t\r\n]', ' ');
    +0082     rows(k, :) = [string(baseRxns{i}), string(enzymeSets{i}), "", formatNumber(applied.ec.kcat(i)), ...
    +0083         "", "custom", "", "", string(note)];
    +0084 end
    +0085 % Isozymic copies of one conventional reaction share a key and a value.
    +0086 if ~isempty(rows)
    +0087     [~, first] = unique(join(rows(:, 1:2), char(1), 2), 'stable');
    +0088     rows = rows(sort(first), :);
    +0089     [~, order] = sort(join(rows(:, [1 2 3 6 4 5 7 8 9]), char(1), 2));
    +0090     rows = rows(order, :);
    +0091 end
    +0092 
    +0093 folder = fileparts(file);
    +0094 if ~isfolder(folder)
    +0095     mkdir(folder);
    +0096 end
    +0097 gecko = strtrim(fileread(fullfile(findGECKOroot(), 'version.txt')));
    +0098 [~, name, ext] = fileparts(inFile);
    +0099 fid = fopen(file, 'w', 'n', 'UTF-8');
    +0100 fprintf(fid, '# source: custom\n');
    +0101 fprintf(fid, '# generator: convertCustomKcats (GECKO %s)\n', gecko);
    +0102 fprintf(fid, '# parameters: {}\n');
    +0103 fprintf(fid, '# data: %s\n', [name ext]);
    +0104 fprintf(fid, '# kind: curated\n');
    +0105 fprintf(fid, '# created: %s\n', char(datetime('now', 'TimeZone', 'UTC', 'Format', 'yyyy-MM-dd''T''HH:mm:ss''Z''')));
    +0106 fprintf(fid, 'rxn\tenzymes\tsubstrate\tkcat\tlog10_sd\tsource\tdetail\tec_code\tnote\n');
    +0107 if ~isempty(rows)
    +0108     fprintf(fid, '%s\n', join(rows, sprintf('\t'), 2));
    +0109 end
    +0110 fclose(fid);
    +0111 report.rows = size(rows, 1);
    +0112 report.partial = notMatch;
    +0113 fprintf('%d custom kcats written to %s.\n', report.rows, file);
    +0114 end
    +0115 
    +0116 function t = formatNumber(x)
    +0117 % The shortest text that reads back as x, as saveKcatSource writes numbers.
    +0118 if x == round(x) && abs(x) < 1e15
    +0119     t = string(sprintf('%d', x));
    +0120     return
    +0121 end
    +0122 for digits = 1:17
    +0123     t = string(sprintf(sprintf('%%.%dg', digits), x));
    +0124     if str2double(t) == x
    +0125         return
    +0126     end
    +0127 end
    +0128 end
    +0129 
    +0130 function checkOptions(args, names, functionName)
    +0131 % Options are name-value pairs with known names, so a misspelled option is
    +0132 % an error instead of being taken as a positional argument.
    +0133 id = [functionName ':arguments'];
    +0134 given = args(1:2:end);
    +0135 if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given))
    +0136     error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', '))
    +0137 end
    +0138 unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names);
    +0139 if ~isempty(unknown)
    +0140     error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ...
    +0141         strjoin(names, ', '))
    +0142 end
    +0143 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/ecStatsFromBrenda.html b/doc/src/gather_kcats/ecStatsFromBrenda.html new file mode 100644 index 00000000..adfb6845 --- /dev/null +++ b/doc/src/gather_kcats/ecStatsFromBrenda.html @@ -0,0 +1,134 @@ + + + + Description of ecStatsFromBrenda + + + + + + + + + +
    Home > src > gather_kcats > ecStatsFromBrenda.m
    + + + +

    ecStatsFromBrenda +

    + +

    PURPOSE ^

    +
    ecStatsFromBrenda Summarise loadBRENDAdata's output per EC number, for
    + +

    SYNOPSIS ^

    +
    function ecStats = ecStatsFromBrenda(KCATcell,SAcell)
    + +

    DESCRIPTION ^

    +
     ecStatsFromBrenda  Summarise loadBRENDAdata's output per EC number, for
    + reviewKcatAssignment's ecStats argument.
    +
    + TODO: verify against a real BRENDA pull before relying on this. Ported
    + from geckopy's ec_stats_from_brenda without being able to run it
    + against real BRENDA data in this environment. In particular,
    + loadBRENDAdata's KCATcell only carries the BRENDA *max* aggregate per
    + (EC, substrate, organism) triple (column 4 of kcat.tsv) -- the median
    + column is read internally but discarded before KCATcell is returned --
    + so kcatMedian below is always NaN, and reviewKcatAssignment's
    + "ec-maximum" check (which needs a finite kcatMedian) will never fire
    + until loadBRENDAdata is extended to also expose it.
    +
    + Parameters
    + ----------
    + KCATcell : cell
    +     as returned by loadBRENDAdata's first output: {ecCode, substrate,
    +     organism, kcatMax}.
    + SAcell : cell
    +     as returned by loadBRENDAdata's second output: {ecCode, organism,
    +     kcatFromSA, mw}.
    +
    + Returns
    + -------
    + ecStats : containers.Map
    +     EC code -> struct(nKcat,kcatMax,kcatMedian,values,nSa), keyed by
    +     the same (uppercased) EC strings BRENDA uses.
    +
    + See also
    + --------
    + reviewKcatAssignment, loadBRENDAdata
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function ecStats = ecStatsFromBrenda(KCATcell,SAcell)
    +0002 % ecStatsFromBrenda  Summarise loadBRENDAdata's output per EC number, for
    +0003 % reviewKcatAssignment's ecStats argument.
    +0004 %
    +0005 % TODO: verify against a real BRENDA pull before relying on this. Ported
    +0006 % from geckopy's ec_stats_from_brenda without being able to run it
    +0007 % against real BRENDA data in this environment. In particular,
    +0008 % loadBRENDAdata's KCATcell only carries the BRENDA *max* aggregate per
    +0009 % (EC, substrate, organism) triple (column 4 of kcat.tsv) -- the median
    +0010 % column is read internally but discarded before KCATcell is returned --
    +0011 % so kcatMedian below is always NaN, and reviewKcatAssignment's
    +0012 % "ec-maximum" check (which needs a finite kcatMedian) will never fire
    +0013 % until loadBRENDAdata is extended to also expose it.
    +0014 %
    +0015 % Parameters
    +0016 % ----------
    +0017 % KCATcell : cell
    +0018 %     as returned by loadBRENDAdata's first output: {ecCode, substrate,
    +0019 %     organism, kcatMax}.
    +0020 % SAcell : cell
    +0021 %     as returned by loadBRENDAdata's second output: {ecCode, organism,
    +0022 %     kcatFromSA, mw}.
    +0023 %
    +0024 % Returns
    +0025 % -------
    +0026 % ecStats : containers.Map
    +0027 %     EC code -> struct(nKcat,kcatMax,kcatMedian,values,nSa), keyed by
    +0028 %     the same (uppercased) EC strings BRENDA uses.
    +0029 %
    +0030 % See also
    +0031 % --------
    +0032 % reviewKcatAssignment, loadBRENDAdata
    +0033 ecCol  = upper(KCATcell{1});
    +0034 maxCol = KCATcell{4};
    +0035 
    +0036 saEcCol = {};
    +0037 if ~isempty(SAcell) && numel(SAcell) >= 1 && ~isempty(SAcell{1})
    +0038     saEcCol = upper(SAcell{1});
    +0039 end
    +0040 
    +0041 ecList = unique([ecCol(:); saEcCol(:)]);
    +0042 ecStats = containers.Map('KeyType','char','ValueType','any');
    +0043 for i = 1:numel(ecList)
    +0044     ec = char(ecList{i});
    +0045     rows = strcmp(ecCol,ec);
    +0046     nKcat = sum(rows);
    +0047     if nKcat > 0
    +0048         kcatMax = max(maxCol(rows));
    +0049         values  = unique(round(maxCol(rows),6));
    +0050     else
    +0051         kcatMax = NaN;
    +0052         values  = [];
    +0053     end
    +0054     nSa = sum(strcmp(saEcCol,ec));
    +0055     ecStats(ec) = struct('nKcat',nKcat,'kcatMax',kcatMax,'kcatMedian',NaN,'values',values,'nSa',nSa);
    +0056 end
    +0057 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/ecTreeEstimate.html b/doc/src/gather_kcats/ecTreeEstimate.html new file mode 100644 index 00000000..49c12867 --- /dev/null +++ b/doc/src/gather_kcats/ecTreeEstimate.html @@ -0,0 +1,212 @@ + + + + Description of ecTreeEstimate + + + + + + + + + +
    Home > src > gather_kcats > ecTreeEstimate.m
    + + + +

    ecTreeEstimate +

    + +

    PURPOSE ^

    +
    ecTreeEstimate EC-tree kcat estimates for EC numbers.
    + +

    SYNOPSIS ^

    +
    function [log10kcat, n, depth, ecUsed] = ecTreeEstimate(eccodes, measurements, k)
    + +

    DESCRIPTION ^

    +
     ecTreeEstimate  EC-tree kcat estimates for EC numbers.
    +
    + For each EC number, the median log10 kcat of its measurements is pulled
    + toward the estimate of its parent class with weight n / (n + k), where n
    + is the number of measurements: the global median, then the 2-digit
    + class, the 3-digit class and the full EC number, in that order. A
    + well-measured EC keeps its own median; a sparsely measured one leans on
    + its class. geckopy has the same (geckopy.gather_kcats.ec_tree.ECTree).
    +
    + Parameters
    + ----------
    + eccodes : cell
    +     per query one or more EC numbers separated by ';'. The one with most
    +     measurements of its full EC is used (the first on a tie).
    + measurements : struct
    +     BRENDA measurement table with fields ec and log10kcat (see
    +     loadBrendaMeasurements).
    + k : double
    +     shrinkage constant (default 5): the number of measurements at which
    +     an EC's own median and its class count equally.
    +
    + Returns
    + -------
    + log10kcat : double
    +     the estimates; the global median for queries without measurements.
    + n : double
    +     number of measurements of the full EC number used.
    + depth : double
    +     deepest EC level with measurements: 4, 3, 2, or 0 when there are
    +     none (or no EC number).
    + ecUsed : cell
    +     the EC number used.
    +
    + Examples
    + --------
    +     m = loadBrendaMeasurements();
    +     [v, n, depth] = ecTreeEstimate({'1.1.1.1'; '2.7.1.1;2.7.1.2'}, m);
    +     kcat = 10.^v;
    +
    + See also
    + --------
    + kcatsFromECTree, loadBrendaMeasurements
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • kcatsFromECTree kcatsFromECTree Estimate kcats from the EC tree and keep them as a source file.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [log10kcat, n, depth, ecUsed] = ecTreeEstimate(eccodes, measurements, k)
    +0002 % ecTreeEstimate  EC-tree kcat estimates for EC numbers.
    +0003 %
    +0004 % For each EC number, the median log10 kcat of its measurements is pulled
    +0005 % toward the estimate of its parent class with weight n / (n + k), where n
    +0006 % is the number of measurements: the global median, then the 2-digit
    +0007 % class, the 3-digit class and the full EC number, in that order. A
    +0008 % well-measured EC keeps its own median; a sparsely measured one leans on
    +0009 % its class. geckopy has the same (geckopy.gather_kcats.ec_tree.ECTree).
    +0010 %
    +0011 % Parameters
    +0012 % ----------
    +0013 % eccodes : cell
    +0014 %     per query one or more EC numbers separated by ';'. The one with most
    +0015 %     measurements of its full EC is used (the first on a tie).
    +0016 % measurements : struct
    +0017 %     BRENDA measurement table with fields ec and log10kcat (see
    +0018 %     loadBrendaMeasurements).
    +0019 % k : double
    +0020 %     shrinkage constant (default 5): the number of measurements at which
    +0021 %     an EC's own median and its class count equally.
    +0022 %
    +0023 % Returns
    +0024 % -------
    +0025 % log10kcat : double
    +0026 %     the estimates; the global median for queries without measurements.
    +0027 % n : double
    +0028 %     number of measurements of the full EC number used.
    +0029 % depth : double
    +0030 %     deepest EC level with measurements: 4, 3, 2, or 0 when there are
    +0031 %     none (or no EC number).
    +0032 % ecUsed : cell
    +0033 %     the EC number used.
    +0034 %
    +0035 % Examples
    +0036 % --------
    +0037 %     m = loadBrendaMeasurements();
    +0038 %     [v, n, depth] = ecTreeEstimate({'1.1.1.1'; '2.7.1.1;2.7.1.2'}, m);
    +0039 %     kcat = 10.^v;
    +0040 %
    +0041 % See also
    +0042 % --------
    +0043 % kcatsFromECTree, loadBrendaMeasurements
    +0044 
    +0045 if nargin < 3 || isempty(k)
    +0046     k = 5;
    +0047 end
    +0048 if ~(isnumeric(k) && isscalar(k) && k > 0)
    +0049     error('ecTreeEstimate:k', 'k must be a positive number.')
    +0050 end
    +0051 if ischar(eccodes) || isstring(eccodes)
    +0052     eccodes = cellstr(eccodes);
    +0053 end
    +0054 ec = measurements.ec(:);
    +0055 v = measurements.log10kcat(:);
    +0056 globalMedian = median(v);
    +0057 lv = cell(4, 1);
    +0058 for d = [2 3 4]
    +0059     if d == 4
    +0060         key = ec;
    +0061     else
    +0062         key = cellfun(@(e) parentEC(e, d), ec, 'UniformOutput', false);
    +0063     end
    +0064     [keys, ~, g] = unique(key);
    +0065     lv{d} = struct('keys', {keys}, 'median', accumarray(g, v, [], @median), ...
    +0066         'n', accumarray(g, 1));
    +0067 end
    +0068 
    +0069 nq = numel(eccodes);
    +0070 log10kcat = repmat(globalMedian, nq, 1);
    +0071 n = zeros(nq, 1);
    +0072 depth = zeros(nq, 1);
    +0073 ecUsed = repmat({''}, nq, 1);
    +0074 for q = 1:nq
    +0075     ecs = strtrim(strsplit(char(eccodes{q}), ';'));
    +0076     ecs = ecs(~cellfun(@isempty, ecs));
    +0077     if isempty(ecs)
    +0078         continue
    +0079     end
    +0080     best = ecs{1};
    +0081     bestN = -1;
    +0082     for e = 1:numel(ecs)
    +0083         c = countOf(lv{4}, ecs{e});
    +0084         if c > bestN
    +0085             best = ecs{e};
    +0086             bestN = c;
    +0087         end
    +0088     end
    +0089     value = globalMedian;
    +0090     for d = [2 3 4]
    +0091         if d == 4
    +0092             key = best;
    +0093         else
    +0094             key = parentEC(best, d);
    +0095         end
    +0096         [c, med] = countOf(lv{d}, key);
    +0097         if c > 0
    +0098             w = c / (c + k);
    +0099             value = w * med + (1 - w) * value;
    +0100             depth(q) = d;
    +0101         end
    +0102     end
    +0103     log10kcat(q) = value;
    +0104     n(q) = bestN;
    +0105     ecUsed{q} = best;
    +0106 end
    +0107 end
    +0108 
    +0109 function p = parentEC(ec, d)
    +0110 parts = strsplit(ec, '.');
    +0111 p = strjoin(parts(1:min(d, numel(parts))), '.');
    +0112 end
    +0113 
    +0114 function [c, med] = countOf(level, key)
    +0115 [found, i] = ismember(key, level.keys);
    +0116 c = 0;
    +0117 med = NaN;
    +0118 if found
    +0119     c = level.n(i);
    +0120     med = level.median(i);
    +0121 end
    +0122 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/extractEnzymeSubstratePairs.html b/doc/src/gather_kcats/extractEnzymeSubstratePairs.html new file mode 100644 index 00000000..707d7f79 --- /dev/null +++ b/doc/src/gather_kcats/extractEnzymeSubstratePairs.html @@ -0,0 +1,225 @@ + + + + Description of extractEnzymeSubstratePairs + + + + + + + + + +
    Home > src > gather_kcats > extractEnzymeSubstratePairs.m
    + + + +

    extractEnzymeSubstratePairs +

    + +

    PURPOSE ^

    +
    extractEnzymeSubstratePairs The enzyme-substrate pairs of an ecModel's reactions.
    + +

    SYNOPSIS ^

    +
    function pairs = extractEnzymeSubstratePairs(model, varargin)
    + +

    DESCRIPTION ^

    +
     extractEnzymeSubstratePairs  The enzyme-substrate pairs of an ecModel's reactions.
    +
    + Lists, for each model.ec reaction, its enzymes and its substrates as
    + DLKcat and the homolog search use them: the reactants of the reaction,
    + without the metabolites of DLKcatIgnoreMets.tsv (metal ions, small
    + molecules), without protein pseudometabolites, and without currency
    + metabolites of DLKcatCurrencyMets.tsv where both members of a pair take
    + part (unless no other substrate remains). Both files are read from the
    + data folder of the project, or else from the databases folder of GECKO.
    + geckopy has the same (extract_enzyme_substrate_pairs).
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + ecRxns : logical
    +     which model.ec.rxns to list (default: all).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + pairs : struct
    +     ecRxn (index into model.ec.rxns), protein (index into model.ec.genes,
    +     model.ec.enzymes and model.ec.sequence) and met (index into
    +     model.mets), one entry per pair, reaction by reaction.
    +
    + Examples
    + --------
    +     pairs = extractEnzymeSubstratePairs(ecModel);
    +     model.metNames(pairs.met(1:5))
    +
    + See also
    + --------
    + writeDLKcatInput, kcatsFromHomologs
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • kcatsFromHomologs kcatsFromHomologs Estimate kcats from measured homologs and keep them as a source file.
    • writeDLKcatInput writeDLKcatInput Prepare and write the input file for DLKcat.
    + + + + +

    SOURCE CODE ^

    +
    0001 function pairs = extractEnzymeSubstratePairs(model, varargin)
    +0002 % extractEnzymeSubstratePairs  The enzyme-substrate pairs of an ecModel's reactions.
    +0003 %
    +0004 % Lists, for each model.ec reaction, its enzymes and its substrates as
    +0005 % DLKcat and the homolog search use them: the reactants of the reaction,
    +0006 % without the metabolites of DLKcatIgnoreMets.tsv (metal ions, small
    +0007 % molecules), without protein pseudometabolites, and without currency
    +0008 % metabolites of DLKcatCurrencyMets.tsv where both members of a pair take
    +0009 % part (unless no other substrate remains). Both files are read from the
    +0010 % data folder of the project, or else from the databases folder of GECKO.
    +0011 % geckopy has the same (extract_enzyme_substrate_pairs).
    +0012 %
    +0013 % Parameters
    +0014 % ----------
    +0015 % model : struct
    +0016 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0017 %
    +0018 % Name-Value Arguments
    +0019 % --------------------
    +0020 % ecRxns : logical
    +0021 %     which model.ec.rxns to list (default: all).
    +0022 % modelAdapter : ModelAdapter
    +0023 %     a loaded model adapter (default: the current default model adapter).
    +0024 %
    +0025 % Returns
    +0026 % -------
    +0027 % pairs : struct
    +0028 %     ecRxn (index into model.ec.rxns), protein (index into model.ec.genes,
    +0029 %     model.ec.enzymes and model.ec.sequence) and met (index into
    +0030 %     model.mets), one entry per pair, reaction by reaction.
    +0031 %
    +0032 % Examples
    +0033 % --------
    +0034 %     pairs = extractEnzymeSubstratePairs(ecModel);
    +0035 %     model.metNames(pairs.met(1:5))
    +0036 %
    +0037 % See also
    +0038 % --------
    +0039 % writeDLKcatInput, kcatsFromHomologs
    +0040 
    +0041 [geckoPath, ~] = findGECKOroot();
    +0042 p = parseGECKOargs(varargin, {'ecRxns', []; 'modelAdapter', []});
    +0043 ecRxnsSel = p.ecRxns;
    +0044 if isempty(ecRxnsSel)
    +0045     ecRxnsSel = true(numel(model.ec.rxns),1);
    +0046 elseif ~islogical(ecRxnsSel)
    +0047     error('ecRxns should be provided as logical vector')
    +0048 elseif numel(ecRxnsSel)~=numel(model.ec.rxns)
    +0049     error('Length of ecRxns is not the same as model.ec.rxns')
    +0050 end
    +0051 ecRxnsSel = find(ecRxnsSel);
    +0052 modelAdapter = p.modelAdapter;
    +0053 if isempty(modelAdapter)
    +0054     modelAdapter = ModelAdapterManager.getDefault();
    +0055     if isempty(modelAdapter)
    +0056         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0057     end
    +0058 end
    +0059 params = modelAdapter.params;
    +0060 
    +0061 if ~model.ec.geckoLight
    +0062    origRxns = model.ec.rxns;
    +0063 else
    +0064    origRxns = extractAfter(model.ec.rxns,4);
    +0065 end
    +0066 origRxnsToInclude = origRxns(ecRxnsSel);
    +0067 
    +0068 % Map back to original reactions, to extract substrates
    +0069 [sanityCheck,origRxnIdxs] = ismember(origRxnsToInclude,model.rxns);
    +0070 if ~all(sanityCheck)
    +0071     error('Not all reactions in model.ec.rxns are found in model.rxns')
    +0072 end
    +0073 
    +0074 % Ignore selected metabolites (metal ions, proteins etc.). First check by
    +0075 % name (case insensitive, without white spaces and special characters),
    +0076 % then also try to match with metSmiles (if available).
    +0077 metsNoSpecialChars = lower(regexprep(model.metNames,'[^0-9a-zA-Z]+',''));
    +0078 if exist(fullfile(params.path,'data','DLKcatIgnoreMets.tsv'),'file')
    +0079     fID        = fopen(fullfile(params.path,'data','DLKcatIgnoreMets.tsv'));
    +0080 else
    +0081     fID        = fopen(fullfile(geckoPath,'databases','DLKcatIgnoreMets.tsv'));
    +0082 end
    +0083 fileData   = textscan(fID,'%s %s','delimiter','\t');
    +0084 fclose(fID);
    +0085 [ignoreMets, ignoreSmiles] = deal(fileData{[1,2]});
    +0086 ignoreMets = lower(regexprep(ignoreMets,'[^0-9a-zA-Z]+',''));
    +0087 ignoreSmiles(cellfun(@isempty,ignoreSmiles)) = [];
    +0088 
    +0089 ignoreMetsIdx  = logical(ismember(metsNoSpecialChars,ignoreMets));
    +0090 if isfield(model,'metSmiles')
    +0091     ignoreMetsIdx = ignoreMetsIdx | logical(ismember(model.metSmiles,ignoreSmiles));
    +0092 end
    +0093 % Also leave out protein-usage pseudometabolites
    +0094 ignoreMetsIdx = ignoreMetsIdx | startsWith(model.mets,'prot_');
    +0095 reducedS = model.S;
    +0096 reducedS(ignoreMetsIdx,:) = 0;
    +0097 
    +0098 % Ignore currency metabolites if they occur in pairs. First check by
    +0099 % name (case insensitive, without white spaces and special characters),
    +0100 % then also try to match with metSmiles (if available).
    +0101 if exist(fullfile(params.path,'data','DLKcatCurrencyMets.tsv'),'file')
    +0102     fID = fopen(fullfile(params.path,'data','DLKcatCurrencyMets.tsv'));
    +0103 else
    +0104     fID = fopen(fullfile(geckoPath,'databases','DLKcatCurrencyMets.tsv'));
    +0105 end
    +0106 fileData = textscan(fID,'%s %s','delimiter','\t');
    +0107 fclose(fID);
    +0108 [currencyMets(:,1), currencyMets(:,2)] = deal(fileData{[1,2]});
    +0109 currencyMets = lower(regexprep(currencyMets,'[^0-9a-zA-Z]+',''));
    +0110 
    +0111 for i=1:size(currencyMets,1)
    +0112     subs = strcmp(currencyMets(i,1),metsNoSpecialChars);
    +0113     prod = strcmp(currencyMets(i,2),metsNoSpecialChars);
    +0114     [~,subsRxns]=find(reducedS(subs,:));
    +0115     [~,prodRxns]=find(reducedS(prod,:));
    +0116     pairRxns = intersect(subsRxns,prodRxns);
    +0117     tempRedS=reducedS;
    +0118     tempRedS([find(subs);find(prod)],pairRxns) = 0;
    +0119     % Do not remove currency mets if no substrate remains
    +0120     rxnsWithRemainingSubstrates = any(tempRedS(:,pairRxns) < 0,1);
    +0121     reducedS([find(subs);find(prod)],intersect(pairRxns,pairRxns(rxnsWithRemainingSubstrates))) = 0;
    +0122 end
    +0123 
    +0124 % origRxnIdxs already selects exactly the model.rxns columns for the requested
    +0125 % ecRxns subset (one column per requested reaction, via origRxns(ecRxns) above), so
    +0126 % clearedRedS needs no further filtering here.
    +0127 clearedRedS = reducedS(:,origRxnIdxs);
    +0128 
    +0129 % Enumerate all substrates for each reaction. clearedRedS has one column per entry
    +0130 % of ecRxnsSel, in that same order, so `reactions` here indexes *that subset*, not
    +0131 % model.ec.rxns directly --- translate back to a real model.ec.rxns index before
    +0132 % using it against model.ec.rxns / model.ec.rxnEnzMat, which are always full-length.
    +0133 [substrates, reactions] = find(clearedRedS<0);
    +0134 globalEcRxns = ecRxnsSel(reactions);
    +0135 
    +0136 % Enumerate all proteins for each reaction
    +0137 [proteins, enzRows] = find(transpose(model.ec.rxnEnzMat(globalEcRxns,:)));
    +0138 pairs.ecRxn   = reshape(globalEcRxns(enzRows), [], 1);
    +0139 pairs.protein = reshape(proteins, [], 1);
    +0140 pairs.met     = reshape(substrates(enzRows), [], 1);
    +0141 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/fetchOpenKineticsPredictor.html b/doc/src/gather_kcats/fetchOpenKineticsPredictor.html new file mode 100644 index 00000000..0291aaba --- /dev/null +++ b/doc/src/gather_kcats/fetchOpenKineticsPredictor.html @@ -0,0 +1,266 @@ + + + + Description of fetchOpenKineticsPredictor + + + + + + + + + +
    Home > src > gather_kcats > fetchOpenKineticsPredictor.m
    + + + +

    fetchOpenKineticsPredictor +

    + +

    PURPOSE ^

    +
    fetchOpenKineticsPredictor Fetch and parse an OpenKineticsPredictor job.
    + +

    SYNOPSIS ^

    +
    function [done, kcatList] = fetchOpenKineticsPredictor(model, varargin)
    + +

    DESCRIPTION ^

    +
     fetchOpenKineticsPredictor  Fetch and parse an OpenKineticsPredictor job.
    +
    + Checks the status of an OpenKineticsPredictor job and, when it has
    + finished, downloads the result to data/OKP_output.csv and parses it (via
    + readOpenKineticsPredictorOutput) into a kcatList consumable by
    + assignKcatValues.
    +
    + The API key (only needed when useStored=false) is resolved from the
    + OKP_API_KEY environment variable or data/okpApiKey.txt; see
    + submitOpenKineticsPredictor for how to obtain and store a key.
    +
    + Parameters
    + ----------
    + model : struct
    +     ecModel in GECKO 3 format (with ecModel.ec structure; model.metSmiles
    +     is required to map results back).
    +
    + Name-Value Arguments
    + --------------------
    + useStored : logical
    +     if true, skip the API entirely and parse the already-downloaded
    +     data/OKP_output.csv. If false, query the API (default false).
    + jobId : char
    +     OKP job id (default: read from data/OKP_job.txt, written by
    +     submitOpenKineticsPredictor).
    + wait : logical
    +     if true, poll until the job finishes; if false, report once and
    +     return (default false).
    + pollInterval : double
    +     seconds between polls when wait=true (default 30).
    + outFile : char
    +     where the result is stored, and read from with useStored=true
    +     (default: data/OKP_output.csv).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + done : logical
    +     true if a result was obtained (downloaded or loaded from disk).
    + kcatList : struct
    +     structure with kcat values (empty when not done); see
    +     readOpenKineticsPredictorOutput for its fields (source, rxns, genes,
    +     substrates, kcats, kcatSource).
    +
    + Examples
    + --------
    +     [done, kcatList] = fetchOpenKineticsPredictor(model);                        % check once
    +     [done, kcatList] = fetchOpenKineticsPredictor(model, 'wait', true);          % poll
    +     [done, kcatList] = fetchOpenKineticsPredictor(model, 'useStored', true);     % parse stored file
    +
    + See also
    + --------
    + submitOpenKineticsPredictor, readOpenKineticsPredictorOutput
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: + +This function is called by: +
      +
    • kcatsFromOKP kcatsFromOKP Gather kcats from OpenKineticsPredictor and keep them as a source file.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [done, kcatList] = fetchOpenKineticsPredictor(model, varargin)
    +0002 % fetchOpenKineticsPredictor  Fetch and parse an OpenKineticsPredictor job.
    +0003 %
    +0004 % Checks the status of an OpenKineticsPredictor job and, when it has
    +0005 % finished, downloads the result to data/OKP_output.csv and parses it (via
    +0006 % readOpenKineticsPredictorOutput) into a kcatList consumable by
    +0007 % assignKcatValues.
    +0008 %
    +0009 % The API key (only needed when useStored=false) is resolved from the
    +0010 % OKP_API_KEY environment variable or data/okpApiKey.txt; see
    +0011 % submitOpenKineticsPredictor for how to obtain and store a key.
    +0012 %
    +0013 % Parameters
    +0014 % ----------
    +0015 % model : struct
    +0016 %     ecModel in GECKO 3 format (with ecModel.ec structure; model.metSmiles
    +0017 %     is required to map results back).
    +0018 %
    +0019 % Name-Value Arguments
    +0020 % --------------------
    +0021 % useStored : logical
    +0022 %     if true, skip the API entirely and parse the already-downloaded
    +0023 %     data/OKP_output.csv. If false, query the API (default false).
    +0024 % jobId : char
    +0025 %     OKP job id (default: read from data/OKP_job.txt, written by
    +0026 %     submitOpenKineticsPredictor).
    +0027 % wait : logical
    +0028 %     if true, poll until the job finishes; if false, report once and
    +0029 %     return (default false).
    +0030 % pollInterval : double
    +0031 %     seconds between polls when wait=true (default 30).
    +0032 % outFile : char
    +0033 %     where the result is stored, and read from with useStored=true
    +0034 %     (default: data/OKP_output.csv).
    +0035 % modelAdapter : ModelAdapter
    +0036 %     a loaded model adapter (default: the current default model adapter).
    +0037 %
    +0038 % Returns
    +0039 % -------
    +0040 % done : logical
    +0041 %     true if a result was obtained (downloaded or loaded from disk).
    +0042 % kcatList : struct
    +0043 %     structure with kcat values (empty when not done); see
    +0044 %     readOpenKineticsPredictorOutput for its fields (source, rxns, genes,
    +0045 %     substrates, kcats, kcatSource).
    +0046 %
    +0047 % Examples
    +0048 % --------
    +0049 %     [done, kcatList] = fetchOpenKineticsPredictor(model);                        % check once
    +0050 %     [done, kcatList] = fetchOpenKineticsPredictor(model, 'wait', true);          % poll
    +0051 %     [done, kcatList] = fetchOpenKineticsPredictor(model, 'useStored', true);     % parse stored file
    +0052 %
    +0053 % See also
    +0054 % --------
    +0055 % submitOpenKineticsPredictor, readOpenKineticsPredictorOutput
    +0056 
    +0057 p = parseGECKOargs(varargin, { ...
    +0058     'useStored',    []; ...
    +0059     'jobId',        []; ...
    +0060     'wait',         []; ...
    +0061     'pollInterval', []; ...
    +0062     'modelAdapter', []; ...
    +0063     'outFile',      []});
    +0064 useStored    = p.useStored;
    +0065 jobId        = p.jobId;
    +0066 wait         = p.wait;
    +0067 pollInterval = p.pollInterval;
    +0068 modelAdapter = p.modelAdapter;
    +0069 
    +0070 if isempty(useStored); useStored = false; end
    +0071 if isempty(modelAdapter)
    +0072     modelAdapter = ModelAdapterManager.getDefault();
    +0073     if isempty(modelAdapter)
    +0074         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0075     end
    +0076 end
    +0077 params = modelAdapter.params;
    +0078 if isempty(wait); wait = false; end
    +0079 if isempty(pollInterval); pollInterval = 30; end
    +0080 
    +0081 outFile = p.outFile;
    +0082 if isempty(outFile)
    +0083     outFile = fullfile(params.path,'data','OKP_output.csv');
    +0084 end
    +0085 
    +0086 %% Stored-result mode: parse the saved file, no API call
    +0087 if useStored
    +0088     if ~exist(outFile,'file')
    +0089         error('useStored=true but no stored result found at %s. Run fetchOpenKineticsPredictor with useStored=false first.', outFile);
    +0090     end
    +0091     kcatList = readOpenKineticsPredictorOutput(model, 'outFile', outFile, 'modelAdapter', modelAdapter);
    +0092     done = true;
    +0093     return
    +0094 end
    +0095 
    +0096 %% API mode
    +0097 apiKey = resolveOkpApiKey('', params.path);
    +0098 
    +0099 if isempty(jobId)
    +0100     jobId = readJobIdFromMeta(fullfile(params.path,'data','OKP_job.txt'));
    +0101 end
    +0102 
    +0103 base = 'https://predictor.openkinetics.org/api/v1';
    +0104 opts = weboptions('HeaderFields', {'Authorization', ['Bearer ' apiKey]}, ...
    +0105                    'Timeout', 60, 'ContentType', 'json');
    +0106 
    +0107 while true
    +0108     statusResp = webread([base '/status/' jobId '/'], opts);
    +0109     state = lower(string(statusResp.status));
    +0110 
    +0111     switch state
    +0112         case "completed"
    +0113             csvText = webread([base '/result/' jobId '/'], ...
    +0114                 weboptions('HeaderFields', {'Authorization', ['Bearer ' apiKey]}, ...
    +0115                            'Timeout', 120, 'ContentType', 'text'));
    +0116             fID = fopen(outFile,'w');
    +0117             fwrite(fID, csvText);
    +0118             fclose(fID);
    +0119             fprintf('OKP job %s completed; result stored at %s\n', jobId, outFile);
    +0120             kcatList = readOpenKineticsPredictorOutput(model, 'outFile', outFile, 'modelAdapter', modelAdapter);
    +0121             done = true;
    +0122             return
    +0123 
    +0124         case "failed"
    +0125             error('OKP job %s failed. Check https://predictor.openkinetics.org/ for details.', jobId);
    +0126 
    +0127         otherwise % pending / running / queued
    +0128             pct = '';
    +0129             if isfield(statusResp,'progress') && isfield(statusResp.progress,'predictionsMade') ...
    +0130                     && isfield(statusResp.progress,'predictionsTotal') && statusResp.progress.predictionsTotal > 0
    +0131                 pct = sprintf(' (%d/%d predictions)', statusResp.progress.predictionsMade, statusResp.progress.predictionsTotal);
    +0132             end
    +0133             if wait
    +0134                 fprintf('OKP job %s status: %s%s. Waiting %d s...\n', jobId, char(statusResp.status), pct, pollInterval);
    +0135                 pause(pollInterval);
    +0136             else
    +0137                 fprintf(['OKP job %s not finished (status: %s%s).\n' ...
    +0138                          'Try again later with fetchOpenKineticsPredictor, ' ...
    +0139                          'or check https://predictor.openkinetics.org/.\n'], ...
    +0140                          jobId, char(statusResp.status), pct);
    +0141                 done = false;
    +0142                 kcatList = [];
    +0143                 return
    +0144             end
    +0145     end
    +0146 end
    +0147 end
    +0148 
    +0149 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0150 function jobId = readJobIdFromMeta(metaFile)
    +0151 if ~exist(metaFile,'file')
    +0152     error(['No jobId provided and no metadata file at %s. Run ' ...
    +0153            'submitOpenKineticsPredictor first, or pass jobId explicitly.'], metaFile);
    +0154 end
    +0155 lines = strsplit(fileread(metaFile), newline);
    +0156 jobId = '';
    +0157 for i=1:numel(lines)
    +0158     tok = regexp(strtrim(lines{i}), '^jobId:\s*(\S+)$', 'tokens', 'once');
    +0159     if ~isempty(tok); jobId = tok{1}; break; end
    +0160 end
    +0161 if isempty(jobId)
    +0162     error('Could not read a jobId from %s.', metaFile);
    +0163 end
    +0164 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/fuzzyKcatMatching.html b/doc/src/gather_kcats/fuzzyKcatMatching.html new file mode 100644 index 00000000..7d535bb6 --- /dev/null +++ b/doc/src/gather_kcats/fuzzyKcatMatching.html @@ -0,0 +1,770 @@ + + + + Description of fuzzyKcatMatching + + + + + + + + + +
    Home > src > gather_kcats > fuzzyKcatMatching.m
    + + + +

    fuzzyKcatMatching +

    + +

    PURPOSE ^

    +
    fuzzyKcatMatching Match model EC numbers and substrates to BRENDA kcats.
    + +

    SYNOPSIS ^

    +
    function kcatList = fuzzyKcatMatching(model, varargin)
    + +

    DESCRIPTION ^

    +
     fuzzyKcatMatching  Match model EC numbers and substrates to BRENDA kcats.
    +
    + Matches the model EC numbers and substrates to the BRENDA database, to
    + return the corresponding kcats for each reaction. If no exact match is
    + found, less specific kcat values are found from (a) evolutionary closely
    + related organism; (b) different substrate; (c) calculated from specific
    + activities; (d) wildcards in the EC number. The model organism is provided
    + in the model adapter as obj.params.org_name, and evolutionary distance to
    + other organisms is determined via KEGG phylogeny. If an organism name
    + occurs multiple times in KEGG, the first instance will be used when
    + determining evolutionary distance.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + ecRxns : logical or double
    +     for which reactions (from model.ec.rxns) kcat values should be found,
    +     provided as a logical vector with the same length as model.ec.rxns
    +     (the reactions are returned in model order), or as indices into
    +     model.ec.rxns (the reactions are returned in the order given, and an
    +     index given twice is returned twice). The literal [] selects all
    +     reactions, which is the default; any other empty selection, such as
    +     find(mask) without true entries, selects none and returns an empty
    +     kcatList.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + forceWClvl : double
    +     number of extra levels, from the right, replaced by a wildcard (on top
    +     of any wildcard already in the code; default 0).
    +
    + Returns
    + -------
    + kcatList : struct
    +     structure array with list of BRENDA derived kcat values, with separate
    +     entries for each kcat value.
    +
    + Notes
    + -----
    + The kcatList structure has the following fields:
    +
    + - source : 'brenda'.
    + - rxns : reaction identifiers.
    + - substrates : substrate names.
    + - kcats : proposed kcat value in /sec.
    + - eccodes : as used to query BRENDA.
    + - wildcardLvl : which level of EC wild-card was necessary to find a match
    +   (0: w.x.y.z; 1: w.x.y.-; 2: w.x.-.-; 3: w.-.-.-; 4: -.-.-.-, which
    +   matches every EC number in BRENDA).
    + - origin : which level of specificity was necessary to find a match
    +   (1: correct organism, correct substrate, kcat; 2: any organism, correct
    +   substrate, kcat; 3: correct organism, any substrate, kcat; 4: any
    +   organism, any substrate, kcat; 5: correct organism, specific activity;
    +   6: any organism, specific activity). Levels are tried in the order
    +   1, 2, 3, 5, 4, 6: a specific activity from the correct organism is
    +   preferred over a kcat from any organism with any substrate. When a
    +   reaction has multiple EC numbers, the EC with the fewest wildcards and
    +   the earliest-tried level is selected, and among those the highest kcat
    +   (the first one when several EC numbers share it); the wildcardLvl and
    +   origin are those of the selected EC.
    +
    + If a wildcard is used, origin levels 1 and 2 are ignored. The last digits
    + in the E.C. number indicate the substrate specificity, so if this should
    + be ignored, then correct substrate matches should not be prioritized.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     kcatList = fuzzyKcatMatching(model);
    +     kcatList = fuzzyKcatMatching(model, 'forceWClvl', 1);
    +
    + See also
    + --------
    + mergeDLKcatAndFuzzyKcats, assignKcatValues
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • kcatsFromBrenda kcatsFromBrenda Gather kcats from BRENDA and keep them as a source file.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function kcatList = fuzzyKcatMatching(model, varargin)
    +0002 % fuzzyKcatMatching  Match model EC numbers and substrates to BRENDA kcats.
    +0003 %
    +0004 % Matches the model EC numbers and substrates to the BRENDA database, to
    +0005 % return the corresponding kcats for each reaction. If no exact match is
    +0006 % found, less specific kcat values are found from (a) evolutionary closely
    +0007 % related organism; (b) different substrate; (c) calculated from specific
    +0008 % activities; (d) wildcards in the EC number. The model organism is provided
    +0009 % in the model adapter as obj.params.org_name, and evolutionary distance to
    +0010 % other organisms is determined via KEGG phylogeny. If an organism name
    +0011 % occurs multiple times in KEGG, the first instance will be used when
    +0012 % determining evolutionary distance.
    +0013 %
    +0014 % Parameters
    +0015 % ----------
    +0016 % model : struct
    +0017 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0018 %
    +0019 % Name-Value Arguments
    +0020 % --------------------
    +0021 % ecRxns : logical or double
    +0022 %     for which reactions (from model.ec.rxns) kcat values should be found,
    +0023 %     provided as a logical vector with the same length as model.ec.rxns
    +0024 %     (the reactions are returned in model order), or as indices into
    +0025 %     model.ec.rxns (the reactions are returned in the order given, and an
    +0026 %     index given twice is returned twice). The literal [] selects all
    +0027 %     reactions, which is the default; any other empty selection, such as
    +0028 %     find(mask) without true entries, selects none and returns an empty
    +0029 %     kcatList.
    +0030 % modelAdapter : ModelAdapter
    +0031 %     a loaded model adapter (default: the current default model adapter).
    +0032 % forceWClvl : double
    +0033 %     number of extra levels, from the right, replaced by a wildcard (on top
    +0034 %     of any wildcard already in the code; default 0).
    +0035 %
    +0036 % Returns
    +0037 % -------
    +0038 % kcatList : struct
    +0039 %     structure array with list of BRENDA derived kcat values, with separate
    +0040 %     entries for each kcat value.
    +0041 %
    +0042 % Notes
    +0043 % -----
    +0044 % The kcatList structure has the following fields:
    +0045 %
    +0046 % - source : 'brenda'.
    +0047 % - rxns : reaction identifiers.
    +0048 % - substrates : substrate names.
    +0049 % - kcats : proposed kcat value in /sec.
    +0050 % - eccodes : as used to query BRENDA.
    +0051 % - wildcardLvl : which level of EC wild-card was necessary to find a match
    +0052 %   (0: w.x.y.z; 1: w.x.y.-; 2: w.x.-.-; 3: w.-.-.-; 4: -.-.-.-, which
    +0053 %   matches every EC number in BRENDA).
    +0054 % - origin : which level of specificity was necessary to find a match
    +0055 %   (1: correct organism, correct substrate, kcat; 2: any organism, correct
    +0056 %   substrate, kcat; 3: correct organism, any substrate, kcat; 4: any
    +0057 %   organism, any substrate, kcat; 5: correct organism, specific activity;
    +0058 %   6: any organism, specific activity). Levels are tried in the order
    +0059 %   1, 2, 3, 5, 4, 6: a specific activity from the correct organism is
    +0060 %   preferred over a kcat from any organism with any substrate. When a
    +0061 %   reaction has multiple EC numbers, the EC with the fewest wildcards and
    +0062 %   the earliest-tried level is selected, and among those the highest kcat
    +0063 %   (the first one when several EC numbers share it); the wildcardLvl and
    +0064 %   origin are those of the selected EC.
    +0065 %
    +0066 % If a wildcard is used, origin levels 1 and 2 are ignored. The last digits
    +0067 % in the E.C. number indicate the substrate specificity, so if this should
    +0068 % be ignored, then correct substrate matches should not be prioritized.
    +0069 %
    +0070 % Examples
    +0071 % --------
    +0072 %     % optional arguments may be given positionally or as name-value pairs:
    +0073 %     kcatList = fuzzyKcatMatching(model);
    +0074 %     kcatList = fuzzyKcatMatching(model, 'forceWClvl', 1);
    +0075 %
    +0076 % See also
    +0077 % --------
    +0078 % mergeDLKcatAndFuzzyKcats, assignKcatValues
    +0079 
    +0080 % Validators reject a name that landed in a positional slot, which
    +0081 % happens when positional and name-value arguments are mixed. Without
    +0082 % them `while forceWClvl > 0` on a char array is all-true and silently
    +0083 % wildcards every EC number.
    +0084 p = parseGECKOargs(varargin, { ...
    +0085     'ecRxns',          [], @(x) assert(isempty(x) || isnumeric(x) || ...
    +0086                                 islogical(x), ...
    +0087                                 'fuzzyKcatMatching:invalidEcRxns', ...
    +0088                                 'ecRxns must be numeric or logical.'); ...
    +0089     'modelAdapter',    [], @(x) assert(isempty(x) || isa(x,'ModelAdapter'), ...
    +0090                                 'fuzzyKcatMatching:invalidModelAdapter', ...
    +0091                                 'modelAdapter must be a ModelAdapter.'); ...
    +0092     'forceWClvl',      [], @(x) assert(isempty(x) || (isnumeric(x) && ...
    +0093                                 isscalar(x) && x >= 0), ...
    +0094                                 'fuzzyKcatMatching:invalidForceWClvl', ...
    +0095                                 'forceWClvl must be a nonnegative scalar.'); ...
    +0096     'kcatAggregation', [], @(x) assert(isempty(x) || any(strcmpi(x, ...
    +0097                                 {'max','median'})), ...
    +0098                                 'fuzzyKcatMatching:invalidKcatAggregation', ...
    +0099                                 'kcatAggregation must be ''max'' or ''median''.')});
    +0100 ecRxns          = p.ecRxns;
    +0101 modelAdapter    = p.modelAdapter;
    +0102 forceWClvl      = p.forceWClvl;
    +0103 kcatAggregation = p.kcatAggregation;
    +0104 
    +0105 % Get indices: [] selects all reactions, a logical vector the true entries (in
    +0106 % model order) and indices are used as given (order and repeats kept).
    +0107 if isnumeric(ecRxns) && isequal(size(ecRxns),[0 0])
    +0108     ecRxns = (1:numel(model.ec.rxns)).';
    +0109 elseif islogical(ecRxns)
    +0110     ecRxns = find(ecRxns(:));
    +0111 else
    +0112     ecRxns = ecRxns(:);
    +0113     if any(ecRxns < 1 | ecRxns > numel(model.ec.rxns) | ecRxns ~= round(ecRxns))
    +0114         error('fuzzyKcatMatching:invalidEcRxns', ...
    +0115             'ecRxns must hold indices of model.ec.rxns.');
    +0116     end
    +0117 end
    +0118 
    +0119 if isempty(modelAdapter)
    +0120     modelAdapter = ModelAdapterManager.getDefault();
    +0121     if isempty(modelAdapter)
    +0122         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0123     end
    +0124 end
    +0125 params = modelAdapter.params;
    +0126 
    +0127 if isempty(forceWClvl)
    +0128     forceWClvl = 0;
    +0129 end
    +0130 
    +0131 if ~isfield(model.ec,'eccodes')
    +0132     error('No EC codes defined in model.ec.eccodes. First run getECfromGEM() and/or getECfromDatabase().')
    +0133 end
    +0134 eccodes      = model.ec.eccodes(ecRxns);
    +0135 if isempty(ecRxns)
    +0136     %No reactions selected: nothing to match, and BRENDA is not read
    +0137     kcatList.source      = 'brenda';
    +0138     kcatList.rxns        = cell(0,1);
    +0139     kcatList.substrates  = cell(0,1);
    +0140     kcatList.kcats       = zeros(0,1);
    +0141     kcatList.eccodes     = cell(0,1);
    +0142     kcatList.wildcardLvl = NaN(0,1);
    +0143     kcatList.origin      = NaN(0,1);
    +0144     return
    +0145 end
    +0146 substrates   = cell(numel(ecRxns),1);
    +0147 substrCoeffs = cell(numel(ecRxns),1);
    +0148 
    +0149 %Need to remove the prefix of GECKO light rxn names in the ec structure
    +0150 if ~model.ec.geckoLight
    +0151     rxnNames = model.ec.rxns;
    +0152 else
    +0153     rxnNames = extractAfter(model.ec.rxns, 4);
    +0154 end
    +0155 [~,originalRxns] = ismember(rxnNames(ecRxns),model.rxns);
    +0156 for i = 1:length(ecRxns)
    +0157     sel = find(model.S(:,originalRxns(i)) < 0);
    +0158     substrates{i}  = model.metNames(sel); 
    +0159     substrCoeffs{i} = -model.S(sel,originalRxns(i));
    +0160 end
    +0161 
    +0162 %Load BRENDA data:
    +0163 kcatAggregation = resolveKcatAggregation(kcatAggregation, modelAdapter);
    +0164 [KCATcell, SAcell] = loadBRENDAdata('modelAdapter', modelAdapter, ...
    +0165     'kcatAggregation', kcatAggregation);
    +0166 
    +0167 %Creates a Structure with KEGG codes for organisms, names and taxonomical
    +0168 %distance matrix and extract the organism index in the KEGG struct
    +0169 phylDistStruct =  KEGG_struct(modelAdapter.getPhylDistStructPath());
    +0170 %Get the KEGG code for the model's organism
    +0171 org_name       = params.org_name;
    +0172 org_index      = find_inKEGG(org_name,phylDistStruct.names);
    +0173 %build an index for genus in the phyl dist struct
    +0174 %first just extract the genus (i.e. the first part of the name)
    +0175 phylDistStruct.genus = lower(regexprep(phylDistStruct.names,'\s.*',''));
    +0176 %create a map for the genuses
    +0177 phylDistStruct.uniqueGenusList = unique(phylDistStruct.genus);
    +0178 phylDistStruct.genusHashMap = containers.Map(phylDistStruct.uniqueGenusList,1:length(phylDistStruct.uniqueGenusList));
    +0179 phylDistStruct.uniqueGenusIndices = cell(length(phylDistStruct.uniqueGenusList),1);
    +0180 
    +0181 %Then for each genus create a list with indices to the names
    +0182 for i = 1:length(phylDistStruct.genus)
    +0183     matchInd = cell2mat(values(phylDistStruct.genusHashMap,phylDistStruct.genus(i)));
    +0184     phylDistStruct.uniqueGenusIndices{matchInd} = [phylDistStruct.uniqueGenusIndices{matchInd};i];
    +0185 end
    +0186 
    +0187 %Allocate output
    +0188 kcats = zeros(length(eccodes),1);
    +0189 mM = length(eccodes);
    +0190 
    +0191 %Create empty kcatInfo
    +0192 %Not returned as an output; used only internally to construct
    +0193 %kcatList.wildcardLvl and kcatList.origin.
    +0194 kcatInfo.info.org_s   = zeros(mM,1);
    +0195 kcatInfo.info.rest_s  = zeros(mM,1);
    +0196 kcatInfo.info.org_ns  = zeros(mM,1);
    +0197 kcatInfo.info.rest_ns = zeros(mM,1);
    +0198 kcatInfo.info.org_sa  = zeros(mM,1);
    +0199 kcatInfo.info.rest_sa = zeros(mM,1);
    +0200 kcatInfo.info.wcLevel = NaN(mM,1);
    +0201 kcatInfo.stats.queries  = 0;
    +0202 kcatInfo.stats.org_s    = 0;
    +0203 kcatInfo.stats.rest_s   = 0;
    +0204 kcatInfo.stats.org_ns   = 0;
    +0205 kcatInfo.stats.rest_ns  = 0;
    +0206 kcatInfo.stats.org_sa   = 0;
    +0207 kcatInfo.stats.rest_sa  = 0;
    +0208 kcatInfo.stats.wc0      = 0;
    +0209 kcatInfo.stats.wc1      = 0;
    +0210 kcatInfo.stats.wc2      = 0;
    +0211 kcatInfo.stats.wc3      = 0;
    +0212 kcatInfo.stats.wc4      = 0;
    +0213 kcatInfo.stats.matrix   = zeros(6,5);
    +0214 
    +0215 %build an EC index to speed things up a bit - many of the ECs appear
    +0216 %many times - unnecessary to compare them all
    +0217 %so, here, each EC string appears only once, and you get a vector with
    +0218 %indices to the rows in KCATcell
    +0219 [ECIndexIds,~,ic] = unique(KCATcell{1});
    +0220 EcIndexIndices = cell(length(ECIndexIds),1);
    +0221 for i = 1:length(EcIndexIndices)
    +0222     EcIndexIndices{i} = find(ic == i).';
    +0223 end
    +0224 
    +0225 %Apply force wildcard level
    +0226 eccodes = forceWildcards(eccodes,forceWClvl);
    +0227 
    +0228 PB = progressReport(mM, 'Gathering kcat values by fuzzy matching to BRENDA database');
    +0229 %Main loop:
    +0230 for i = 1:mM
    +0231     PB.count;
    +0232     %Match:
    +0233     EC = eccodes{i};
    +0234     if ~isempty(EC)
    +0235         EC = strsplit(EC,';');
    +0236         %Try to match direct reaction:
    +0237         if ~isempty(substrates{i})
    +0238             [kcats(i), kcatInfo.info,kcatInfo.stats] = iterativeMatch(EC,substrates{i},substrCoeffs{i},i,KCATcell,...
    +0239                 kcatInfo.info,kcatInfo.stats,org_name,...
    +0240                 phylDistStruct,org_index,SAcell,ECIndexIds,EcIndexIndices,kcatAggregation);
    +0241         end
    +0242     end
    +0243 end
    +0244 
    +0245 kcatList.source      = 'brenda';
    +0246 kcatList.rxns        = model.ec.rxns(ecRxns);
    +0247 kcatList.substrates  = substrates;
    +0248 kcatList.kcats       = kcats;
    +0249 kcatList.eccodes     = eccodes;
    +0250 kcatList.wildcardLvl = kcatInfo.info.wcLevel;
    +0251 kcatList.origin      = NaN(numel(model.ec.rxns(ecRxns)),1);
    +0252 % This can be refactored, iterativeMatch and their nested functions can
    +0253 % just directly report the origin number.
    +0254 origin = [kcatInfo.info.org_s kcatInfo.info.rest_s kcatInfo.info.org_ns kcatInfo.info.rest_ns kcatInfo.info.org_sa kcatInfo.info.rest_sa];
    +0255 for i=1:6
    +0256     kcatList.origin(find(origin(:,i))) = i;
    +0257 end
    +0258 end
    +0259 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0260 %Replaces the rightmost level of each EC code that is not a wildcard yet with
    +0261 %a wildcard, forceWClvl times, so that level 4 gives -.-.-.- . The codes of one
    +0262 %entry are separated by ';'. A code that does not have four levels is kept.
    +0263 function eccodes = forceWildcards(eccodes,forceWClvl)
    +0264 if forceWClvl <= 0
    +0265     return
    +0266 end
    +0267 for i = 1:numel(eccodes)
    +0268     if isempty(eccodes{i})
    +0269         continue
    +0270     end
    +0271     codes = strsplit(eccodes{i},';');
    +0272     for j = 1:numel(codes)
    +0273         parts = strsplit(codes{j},'.');
    +0274         if numel(parts) ~= 4
    +0275             continue
    +0276         end
    +0277         for k = 1:forceWClvl
    +0278             last = find(~strcmp(parts,'-'),1,'last');
    +0279             if isempty(last)
    +0280                 break
    +0281             end
    +0282             parts{last} = '-';
    +0283         end
    +0284         codes{j} = strjoin(parts,'.');
    +0285     end
    +0286     eccodes{i} = strjoin(codes,';');
    +0287 end
    +0288 end
    +0289 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0290 function [kcat,dir,tot] =iterativeMatch(EC,subs,substrCoeff,i,KCATcell,dir,tot,...
    +0291     name,phylDist,org_index,SAcell,ECIndexIds,EcIndexIndices,kcatAggregation)
    +0292 %Will iteratively try to match the EC number to some registry in BRENDA,
    +0293 %using each time one additional wildcard.
    +0294 
    +0295 kcat    = zeros(size(EC));
    +0296 origin  = zeros(size(EC));
    +0297 matches = zeros(size(EC));
    +0298 wc_num  = ones(size(EC)).*1000;
    +0299 for k = 1:length(EC)
    +0300     success  = false;
    +0301     while ~success
    +0302         %Atempt match:
    +0303         [kcat(k),origin(k),matches(k)] = mainMatch(EC{k},subs,substrCoeff,KCATcell,...
    +0304             name,phylDist,...
    +0305             org_index,SAcell,ECIndexIds,EcIndexIndices,kcatAggregation);
    +0306         %If any match found, ends. If not, introduces one extra wild card and
    +0307         %tries again:
    +0308         if origin(k) > 0
    +0309             success   = true;
    +0310             wc_num(k) = sum(EC{k}=='-');
    +0311         else
    +0312             wild_num = sum(EC{k}=='-');
    +0313             if numel(strsplit(EC{k},'.')) ~= 4
    +0314                 %An EC code without four levels (for example '1.1.1') cannot be
    +0315                 %escalated level by level: stop with the no-match values, as
    +0316                 %geckopy does.
    +0317                 success = true;
    +0318             elseif wild_num >= 4
    +0319                 %Already fully wildcarded ('-.-.-.-') and still no match --
    +0320                 %stop here instead of computing dot_pos(4-wild_num) with
    +0321                 %wild_num==4, an out-of-range index. kcat(k)/origin(k) keep
    +0322                 %their zero-initialised "no match" values.
    +0323                 success = true;
    +0324             elseif wild_num == 3
    +0325                 %Last escalation: '-.-.-.-' matches every EC number in BRENDA
    +0326                 EC{k} = '-.-.-.-';
    +0327             else
    +0328                 dot_pos  = [2 strfind(EC{k},'.')];
    +0329                 wc_text  = '-.-.-.-';
    +0330                 EC{k}    = [EC{k}(1:dot_pos(4-wild_num)) wc_text(1:2*wild_num+1)];
    +0331             end
    +0332         end
    +0333     end
    +0334 end
    +0335 
    +0336 if sum(origin) > 0
    +0337     %For more than one EC: Choose the maximum value among the ones with the
    +0338     %less amount of wildcards and the better origin:
    +0339     best_pos    = (wc_num == min(wc_num));
    +0340     new_origin  = origin(best_pos);
    +0341     best_origin = min(new_origin(new_origin~=0));
    +0342     %Intersect with the wildcard filter above -- comparing origin==best_origin
    +0343     %against the full (unfiltered) origin vector would let an EC with a worse
    +0344     %(higher) wildcard count back in whenever it happens to share best_origin,
    +0345     %defeating the wildcard-count filter entirely.
    +0346     best_pos    = best_pos & (origin == best_origin);
    +0347     %Highest kcat among those, the first one if several share it
    +0348     best_idx   = find(best_pos);
    +0349     [~,j]      = max(kcat(best_idx));
    +0350     max_pos    = best_idx(j);
    +0351     wc_num     = wc_num(max_pos);
    +0352     origin     = origin(max_pos);
    +0353     matches    = matches(max_pos);
    +0354     kcat       = kcat(max_pos);
    +0355 
    +0356     %Update dir and tot:
    +0357     dir.org_s(i)   = matches*(origin == 1);
    +0358     dir.rest_s(i)  = matches*(origin == 2);
    +0359     dir.org_ns(i)  = matches*(origin == 3);
    +0360     dir.org_sa(i)  = matches*(origin == 4);
    +0361     dir.rest_ns(i) = matches*(origin == 5);
    +0362     dir.rest_sa(i) = matches*(origin == 6);
    +0363     dir.wcLevel(i) = wc_num;
    +0364     tot.org_s        = tot.org_s   + (origin == 1);
    +0365     tot.rest_s       = tot.rest_s  + (origin == 2);
    +0366     tot.org_ns       = tot.org_ns  + (origin == 3);
    +0367     tot.org_sa       = tot.org_sa  + (origin == 4);
    +0368     tot.rest_ns      = tot.rest_ns + (origin == 5);
    +0369     tot.rest_sa      = tot.rest_sa + (origin == 6);
    +0370     tot.wc0          = tot.wc0     + (wc_num == 0);
    +0371     tot.wc1          = tot.wc1     + (wc_num == 1);
    +0372     tot.wc2          = tot.wc2     + (wc_num == 2);
    +0373     tot.wc3          = tot.wc3     + (wc_num == 3);
    +0374     tot.wc4          = tot.wc4     + (wc_num == 4);
    +0375     tot.queries      = tot.queries + 1;
    +0376     tot.matrix(origin,wc_num+1) = tot.matrix(origin,wc_num+1) + 1;
    +0377 end
    +0378 
    +0379 end
    +0380 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0381 
    +0382 function [kcat,origin,matches] = mainMatch(EC,subs,substrCoeff,KCATcell,...
    +0383     name,phylDist,org_index,SAcell,ECIndexIds,EcIndexIndices,kcatAggregation)
    +0384 
    +0385 %First make the string matching. This takes time, so we only want to do
    +0386 %this once:
    +0387 %Relaxes matching if wild cards are present:
    +0388 wild     = false;
    +0389 wild_pos = strfind(EC,'-');
    +0390 if ~isempty(wild_pos)
    +0391     EC   = EC(1:wild_pos(1)-1);
    +0392     wild = true;
    +0393 end
    +0394 stringMatchesEC_cell = extract_string_matches(EC,KCATcell{1},wild,ECIndexIds,EcIndexIndices);
    +0395 
    +0396 % Matching function prioritizing organism and substrate specificity when
    +0397 % available.
    +0398 
    +0399 origin = 0;
    +0400 %First try to match organism and substrate:
    +0401 [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,name,true,false,...
    +0402     phylDist,org_index,SAcell,stringMatchesEC_cell,[],kcatAggregation);
    +0403 if matches > 0 && ~wild % If wildcard, ignore substrate match
    +0404     origin = 1;
    +0405     %If no match, try the closest organism but match the substrate:
    +0406 else
    +0407     [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,'',true,false,...
    +0408         phylDist,org_index,SAcell,stringMatchesEC_cell,[],kcatAggregation);
    +0409     if matches > 0 && ~wild % If wildcard, ignore substrate match
    +0410         origin = 2;
    +0411         %If no match, try to match organism but with any substrate:
    +0412     else
    +0413         [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,name,false,false,...
    +0414             phylDist,org_index,SAcell,stringMatchesEC_cell,[],kcatAggregation);
    +0415         if matches > 0
    +0416             origin = 3;
    +0417             %If no match, try to match organism but for any substrate (SA*MW):
    +0418         else
    +0419             %create matching index for SA, has not been needed until now
    +0420             stringMatchesSA = extract_string_matches(EC,SAcell{1},wild,[],[]);
    +0421 
    +0422             [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,name,false,...
    +0423                 true,phylDist,org_index,...
    +0424                 SAcell,stringMatchesEC_cell,stringMatchesSA,kcatAggregation);
    +0425             if matches > 0
    +0426                 origin = 4;
    +0427                 %If no match, try any organism and any substrate:
    +0428             else
    +0429                 [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,'',false,...
    +0430                     false,phylDist,...
    +0431                     org_index,SAcell,stringMatchesEC_cell,stringMatchesSA,kcatAggregation);
    +0432                 if matches > 0
    +0433                     origin = 5;
    +0434                     %Again if no match, look for any org and SA*MW
    +0435                 else
    +0436                     [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,'',...
    +0437                         false,true,phylDist,...
    +0438                         org_index,SAcell,stringMatchesEC_cell,stringMatchesSA,kcatAggregation);
    +0439                     if matches > 0
    +0440                         origin = 6;
    +0441                     end
    +0442                 end
    +0443 
    +0444             end
    +0445         end
    +0446     end
    +0447 end
    +0448 end
    +0449 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0450 function [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,organism,...
    +0451     substrate,SA,phylDist,...
    +0452     org_index,SAcell,KCATcellMatches,SAcellMatches,kcatAggregation)
    +0453 
    +0454 %Will go through BRENDA and will record any match. Afterwards, it will
    +0455 %return the maximum value and the number of matches attained.
    +0456 kcat    = [];
    +0457 matches = 0;
    +0458 
    +0459 if SA
    +0460     %SAcell{1},wild,[],[]
    +0461     EC_indexes = extract_indexes(SAcellMatches,[],SAcell{2},subs,substrate,...
    +0462         organism,org_index,phylDist);
    +0463 
    +0464     kcat       = SAcell{3}(EC_indexes);
    +0465     org_cell   = SAcell{2}(EC_indexes);
    +0466     MW_BRENDA  = SAcell{4}(EC_indexes);
    +0467 
    +0468 else
    +0469     %KCATcell{1},wild,ECIndexIds,EcIndexIndices
    +0470     EC_indexes = extract_indexes(KCATcellMatches,KCATcell{2},KCATcell{3},...
    +0471         subs,substrate,organism,org_index,...
    +0472         phylDist);
    +0473     if substrate
    +0474         for j = 1:length(EC_indexes)
    +0475             indx = EC_indexes(j);
    +0476             for k = 1:length(subs)
    +0477                 if (isempty(subs{k}))
    +0478                     break;
    +0479                 end
    +0480                 %l = logical(strcmpi(model.metNames,subs{k}).*(model.S(:,i)~=0)); %I don't understand the .* (model.S(:,i)~=0) part, it shouldn't be needed?/JG;
    +0481                 if ~isempty(subs{k}) && strcmpi(subs{k},KCATcell{2}(indx))
    +0482                     if KCATcell{4}(indx) > 0
    +0483                         coeff = substrCoeff(k);
    +0484                         kCatTmp = KCATcell{4}(indx);
    +0485                         kcat  = [kcat;kCatTmp/coeff];
    +0486                     end
    +0487                 end
    +0488             end
    +0489         end
    +0490     else
    +0491         kcat = KCATcell{4}(EC_indexes);
    +0492     end
    +0493 end
    +0494 %Collapse the matched entries to one value, by the chosen aggregation:
    +0495 if isempty(kcat)
    +0496     kcat = 0;
    +0497 else
    +0498     matches = length(kcat);
    +0499     if strcmpi(kcatAggregation,'median')
    +0500         kcat = median(kcat);
    +0501     else
    +0502         kcat = max(kcat);
    +0503     end
    +0504 end
    +0505 %Avoid SA*Mw values over the diffusion limit rate  [Bar-Even et al. 2011]
    +0506 if kcat>(1E7)
    +0507     kcat = 1E7;
    +0508 end
    +0509 end
    +0510 
    +0511 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0512 %Make the string matches of the ECs. This is heavy, so only do it once!
    +0513 %
    +0514 function EC_indexes = extract_string_matches(EC,EC_cell,wild,ECIndexIds,EcIndexIndices)
    +0515 EC_indexes = [];
    +0516 EC_indexesOld = [];
    +0517 if wild
    +0518     if (~isempty(ECIndexIds)) %In some cases the EC_cell is not from KCatCell
    +0519         % startsWith, not contains: EC is a truncated prefix like '1.' (everything
    +0520         % before the first wildcard dash), and an anchored match is what the
    +0521         % non-optimized branch below already does (strfind(...)==1). contains()
    +0522         % would match that same '1.' substring anywhere in the string, not just at
    +0523         % the start -- '4.2.1.1' contains '1.' between its third and fourth levels,
    +0524         % so a '1.-.-.-' wildcard query for enzyme class 1 would also match entries
    +0525         % from unrelated classes whose EC code happens to contain the same two
    +0526         % characters.
    +0527         X = find(startsWith(ECIndexIds, EC));
    +0528         for j = 1:length(X)
    +0529             EC_indexes = [EC_indexes,EcIndexIndices{X(j)}];
    +0530         end
    +0531     elseif isempty(EC) %Not optimized, fully wildcarded: every entry matches
    +0532         EC_indexes = 1:length(EC_cell);
    +0533     else %Not optimized
    +0534         for j=1:length(EC_cell)
    +0535             if strfind(EC_cell{j},EC)==1
    +0536                 EC_indexes = [EC_indexes,j];
    +0537             end
    +0538         end
    +0539     end
    +0540 else
    +0541     if (~isempty(ECIndexIds)) %In some cases the EC_cell is not from KCatCell
    +0542         mtch = find(strcmpi(EC,ECIndexIds));
    +0543         if (~isempty(mtch))
    +0544             EC_indexes = EcIndexIndices{mtch};
    +0545         end
    +0546     else %%Not optimized
    +0547         if ~isempty(EC_cell)
    +0548             EC_indexes = transpose(find(strcmpi(EC,EC_cell)));
    +0549         end
    +0550     end
    +0551 end
    +0552 
    +0553 end
    +0554 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0555 %Extract the indexes of the entries in the BRENDA data that meet the
    +0556 %conditions specified by the search criteria
    +0557 function EC_indexes = extract_indexes(EC_indCellStringMatches,subs_cell,orgs_cell,subs,...
    +0558     substrate,organism, org_index,...
    +0559     phylDist)
    +0560 
    +0561 EC_indexes = EC_indCellStringMatches;%reuse so the string comparisons are not run many times
    +0562 
    +0563 %If substrate=true then it will extract only the substrates appereances
    +0564 %indexes in the EC subset from the BRENDA cell array
    +0565 
    +0566 if substrate
    +0567     if (~isempty(EC_indexes)) %optimization
    +0568         Subs_indexes = [];
    +0569         for l = 1:length(subs)
    +0570             if (isempty(subs{l}))
    +0571                 break;
    +0572             end
    +0573             Subs_indexes = horzcat(Subs_indexes,EC_indexes(strcmpi(subs(l),...
    +0574                 subs_cell(EC_indexes))));
    +0575         end
    +0576         EC_indexes = Subs_indexes;
    +0577     end
    +0578 end
    +0579 
    +0580 EC_orgs = orgs_cell(EC_indexes);
    +0581 %If specific organism values are requested looks for all the organism
    +0582 %repetitions on the subset BRENDA cell array(EC_indexes)
    +0583 if string(organism) ~= ''
    +0584     EC_indexes = EC_indexes(strcmpi(string(organism),EC_orgs));
    +0585 
    +0586     %If KEGG code was assigned to the organism (model) then it will look for
    +0587     %the Kcat value for the closest organism
    +0588 elseif org_index~='*' %&& org_index~=''
    +0589     KEGG_indexes = [];temp = [];
    +0590 
    +0591     %For relating a phyl dist between the modelled organism and the organisms
    +0592     %on the BRENDA cell array it should search for a KEGG code for each of
    +0593     %these
    +0594     for j=1:length(EC_indexes)
    +0595         %Assigns a KEGG index for those found on the KEGG struct
    +0596         orgs_index = find(strcmpi(orgs_cell(EC_indexes(j)),phylDist.names),1);
    +0597         if ~isempty(orgs_index)
    +0598             KEGG_indexes = [KEGG_indexes; orgs_index];
    +0599             temp         = [temp;EC_indexes(j)];
    +0600             %For values related to organisms without KEGG code, then it will
    +0601             %look for KEGG code for the first organism with the same genus
    +0602         else
    +0603             org = orgs_cell{EC_indexes(j)};
    +0604             orgGenus = lower(regexprep(org,'\s.*',''));
    +0605             if isKey(phylDist.genusHashMap,orgGenus) %annoyingly, this seems to be needed
    +0606                 matchInd = cell2mat(values(phylDist.genusHashMap,{orgGenus}));
    +0607                 matches = phylDist.uniqueGenusIndices{matchInd};
    +0608                 k = matches(1);
    +0609                 KEGG_indexes = [KEGG_indexes;k];
    +0610                 temp         = [temp;EC_indexes(j)];
    +0611             end
    +0612         end
    +0613     end
    +0614     %Update the EC_indexes cell array
    +0615     EC_indexes = temp;
    +0616     %Looks for the taxonomically closest organism and saves the index of
    +0617     %its appearences in the BRENDA cell
    +0618     if ~isempty(EC_indexes)
    +0619         distances = phylDist.distMat(org_index,KEGG_indexes);
    +0620         EC_indexes = EC_indexes(distances == min(distances));
    +0621     end
    +0622 end
    +0623 end
    +0624 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0625 function org_index = find_inKEGG(org_name,names)
    +0626 org_index      = find(strcmpi(org_name,names));
    +0627 if numel(org_index)>1
    +0628     org_index = org_index(1);
    +0629 elseif isempty(org_index)
    +0630     org_name    = regexprep(org_name,'\s.*','');
    +0631     org_index   = find(strcmpi(org_name,names));
    +0632     if numel(org_index)>1
    +0633         org_index = org_index(1);
    +0634     elseif isempty(org_index)
    +0635         org_index = '*';
    +0636     end
    +0637 end
    +0638 end
    +0639 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0640 function phylDistStruct =  KEGG_struct(phylpath)
    +0641 load(phylpath)
    +0642 phylDistStruct.ids   = transpose(phylDistStruct.ids);
    +0643 phylDistStruct.names = transpose(phylDistStruct.names);
    +0644 phylDistStruct.names = regexprep(phylDistStruct.names,'\s*\(.*','');
    +0645 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/getEcRxnKeys.html b/doc/src/gather_kcats/getEcRxnKeys.html new file mode 100644 index 00000000..81685081 --- /dev/null +++ b/doc/src/gather_kcats/getEcRxnKeys.html @@ -0,0 +1,127 @@ + + + + Description of getEcRxnKeys + + + + + + + + + +
    Home > src > gather_kcats > getEcRxnKeys.m
    + + + +

    getEcRxnKeys +

    + +

    PURPOSE ^

    +
    getEcRxnKeys Build-independent keys of the model.ec reactions.
    + +

    SYNOPSIS ^

    +
    function [baseRxns, enzymeSets] = getEcRxnKeys(model)
    + +

    DESCRIPTION ^

    +
     getEcRxnKeys  Build-independent keys of the model.ec reactions.
    +
    + A kcat source file (see saveKcatSource) identifies a reaction by its
    + conventional reaction and its enzyme set, not by model.ec.rxns, whose
    + identifiers depend on how the ecModel was built. This function gives
    + both keys for every model.ec row.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Returns
    + -------
    + baseRxns : cell
    +     per model.ec.rxns entry, the conventional reaction: without a
    +     trailing _EXP_<n> (full model) or a leading <nnn>_ (light model). A
    +     reverse direction keeps its _REV.
    + enzymeSets : cell
    +     per model.ec.rxns entry, the UniProt accessions of its enzymes
    +     (model.ec.rxnEnzMat), sorted and joined by ' + '; empty without
    +     enzymes.
    +
    + Examples
    + --------
    +     [baseRxns, enzymeSets] = getEcRxnKeys(ecModel);
    +
    + See also
    + --------
    + saveKcatSource, loadKcatSource
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • convertCustomKcats convertCustomKcats Convert data/customKcats.tsv into data/kcats/custom.tsv.
    • loadKcatSource loadKcatSource Read a kcat source file and map its rows to an ecModel.
    • saveKcatSource saveKcatSource Write a kcatList to a kcat source file of the project.
    + + + + +

    SOURCE CODE ^

    +
    0001 function [baseRxns, enzymeSets] = getEcRxnKeys(model)
    +0002 % getEcRxnKeys  Build-independent keys of the model.ec reactions.
    +0003 %
    +0004 % A kcat source file (see saveKcatSource) identifies a reaction by its
    +0005 % conventional reaction and its enzyme set, not by model.ec.rxns, whose
    +0006 % identifiers depend on how the ecModel was built. This function gives
    +0007 % both keys for every model.ec row.
    +0008 %
    +0009 % Parameters
    +0010 % ----------
    +0011 % model : struct
    +0012 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0013 %
    +0014 % Returns
    +0015 % -------
    +0016 % baseRxns : cell
    +0017 %     per model.ec.rxns entry, the conventional reaction: without a
    +0018 %     trailing _EXP_<n> (full model) or a leading <nnn>_ (light model). A
    +0019 %     reverse direction keeps its _REV.
    +0020 % enzymeSets : cell
    +0021 %     per model.ec.rxns entry, the UniProt accessions of its enzymes
    +0022 %     (model.ec.rxnEnzMat), sorted and joined by ' + '; empty without
    +0023 %     enzymes.
    +0024 %
    +0025 % Examples
    +0026 % --------
    +0027 %     [baseRxns, enzymeSets] = getEcRxnKeys(ecModel);
    +0028 %
    +0029 % See also
    +0030 % --------
    +0031 % saveKcatSource, loadKcatSource
    +0032 
    +0033 if model.ec.geckoLight
    +0034     baseRxns = regexprep(model.ec.rxns, '^\d+_', '');
    +0035 else
    +0036     baseRxns = regexprep(model.ec.rxns, '_EXP_\d+$', '');
    +0037 end
    +0038 baseRxns = baseRxns(:);
    +0039 
    +0040 n = numel(model.ec.rxns);
    +0041 enzymeSets = repmat({''}, n, 1);
    +0042 [rows, cols] = find(model.ec.rxnEnzMat);
    +0043 if ~isempty(rows)
    +0044     % Enzymes per reaction in one pass, rather than a search per reaction.
    +0045     perRxn = accumarray(rows(:), cols(:), [n 1], @(c) {c});
    +0046     for i = find(~cellfun(@isempty, perRxn))'
    +0047         enzymes = unique(model.ec.enzymes(perRxn{i}));
    +0048         enzymeSets{i} = strjoin(enzymes(:)', ' + ');
    +0049     end
    +0050 end
    +0051 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/getStandardKcat.html b/doc/src/gather_kcats/getStandardKcat.html new file mode 100644 index 00000000..bc9f3d9f --- /dev/null +++ b/doc/src/gather_kcats/getStandardKcat.html @@ -0,0 +1,483 @@ + + + + Description of getStandardKcat + + + + + + + + + +
    Home > src > gather_kcats > getStandardKcat.m
    + + + +

    getStandardKcat +

    + +

    PURPOSE ^

    +
    getStandardKcat Assign standard kcat and MW to reactions without enzymes.
    + +

    SYNOPSIS ^

    +
    function [model, rxnsMissingGPR, standardMW, standardKcat, rxnsNoKcat] = getStandardKcat(model, varargin)
    + +

    DESCRIPTION ^

    +
     getStandardKcat  Assign standard kcat and MW to reactions without enzymes.
    +
    + Calculates a standard kcat and standard molecular weight (MW) that can be
    + used to apply enzyme constraints to reactions without any associated
    + enzymes. Such reactions have either an empty model.grRules field, or they
    + have no match in model.ec.rxns (which can be the case if the genes in the
    + model.grRules field could not be mapped to enzymes). This is done by
    + adding those reactions to model.ec, assigning a "standard" pseudoenzyme
    + with the standard MW (median of all proteins in the organism) and standard
    + kcat (median from all kcat, or subsystem specific kcat).
    +
    + A reaction is assigned a subSystem specific kcat value if the model has a
    + subSystems field and the reaction is annotated with a subSystem. Only the
    + first subSystem will be considered if multiple are annotated to the same
    + reaction.
    +
    + Exchange, transport and pseudoreactions are filtered out, plus any
    + reaction identifiers specified in /data/pseudoRxns.tsv in the model
    + adapter folder.
    +
    + In addition, reactions that are annotated with an enzyme (and therefore
    + already in model.ec), but not assigned any reaction-specific kcat value
    + (their model.ec.kcat entry is either 0 or NaN), can be assigned standard
    + kcat values by a similar approach. However, those reactions will not be
    + linked to the "standard" pseudoenzyme, but will use the enzyme that they
    + had already been associated with.
    +
    + Any pre-existing standard kcat assignments (identified by 'standard'
    + entries in model.ec.source) are removed when applying this function.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + threshold : double
    +     a threshold to determine whether to use a kcat value based on the
    +     median kcat of the reactions in the same subSystem or based on the
    +     median value of all the kcat in the model. The second option is used
    +     when the number of reactions in a determined subSystem with a real
    +     (nonzero, non-NaN) kcat value is < threshold (default 10).
    + fillZeroKcat : logical
    +     whether zero kcat values should be replaced with standard kcat values
    +     (default true).
    +
    + Returns
    + -------
    + model : struct
    +     ecModel where model.ec is expanded with a standard protein with
    +     standard kcat and standard MW, assigned to reactions without gene
    +     associations.
    + rxnsMissingGPR : cell
    +     a list of updated rxns identifiers with a standard value.
    + standardMW : double
    +     the standard MW value calculated.
    + standardKcat : double
    +     the standard kcat value calculated.
    + rxnsNoKcat : cell
    +     a list of rxns identifiers whose zero kcat has been replaced.
    +
    + Notes
    + -----
    + While model.ec.kcat is populated, applyKcatConstraints would still need to
    + be run to apply the new constraints to the S-matrix.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     [model, rxnsMissingGPR, standardMW, standardKcat, rxnsNoKcat] = getStandardKcat(model);
    +     [model, rxnsMissingGPR, standardMW, standardKcat, rxnsNoKcat] = getStandardKcat(model, 'threshold', 20);
    +
    + See also
    + --------
    + removeStandardKcat, applyKcatConstraints
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • collectKcats collectKcats Decide one kcat per reaction from the kcat source files.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [model, rxnsMissingGPR, standardMW, standardKcat, rxnsNoKcat] = getStandardKcat(model, varargin)
    +0002 % getStandardKcat  Assign standard kcat and MW to reactions without enzymes.
    +0003 %
    +0004 % Calculates a standard kcat and standard molecular weight (MW) that can be
    +0005 % used to apply enzyme constraints to reactions without any associated
    +0006 % enzymes. Such reactions have either an empty model.grRules field, or they
    +0007 % have no match in model.ec.rxns (which can be the case if the genes in the
    +0008 % model.grRules field could not be mapped to enzymes). This is done by
    +0009 % adding those reactions to model.ec, assigning a "standard" pseudoenzyme
    +0010 % with the standard MW (median of all proteins in the organism) and standard
    +0011 % kcat (median from all kcat, or subsystem specific kcat).
    +0012 %
    +0013 % A reaction is assigned a subSystem specific kcat value if the model has a
    +0014 % subSystems field and the reaction is annotated with a subSystem. Only the
    +0015 % first subSystem will be considered if multiple are annotated to the same
    +0016 % reaction.
    +0017 %
    +0018 % Exchange, transport and pseudoreactions are filtered out, plus any
    +0019 % reaction identifiers specified in /data/pseudoRxns.tsv in the model
    +0020 % adapter folder.
    +0021 %
    +0022 % In addition, reactions that are annotated with an enzyme (and therefore
    +0023 % already in model.ec), but not assigned any reaction-specific kcat value
    +0024 % (their model.ec.kcat entry is either 0 or NaN), can be assigned standard
    +0025 % kcat values by a similar approach. However, those reactions will not be
    +0026 % linked to the "standard" pseudoenzyme, but will use the enzyme that they
    +0027 % had already been associated with.
    +0028 %
    +0029 % Any pre-existing standard kcat assignments (identified by 'standard'
    +0030 % entries in model.ec.source) are removed when applying this function.
    +0031 %
    +0032 % Parameters
    +0033 % ----------
    +0034 % model : struct
    +0035 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0036 %
    +0037 % Name-Value Arguments
    +0038 % --------------------
    +0039 % modelAdapter : ModelAdapter
    +0040 %     a loaded model adapter (default: the current default model adapter).
    +0041 % threshold : double
    +0042 %     a threshold to determine whether to use a kcat value based on the
    +0043 %     median kcat of the reactions in the same subSystem or based on the
    +0044 %     median value of all the kcat in the model. The second option is used
    +0045 %     when the number of reactions in a determined subSystem with a real
    +0046 %     (nonzero, non-NaN) kcat value is < threshold (default 10).
    +0047 % fillZeroKcat : logical
    +0048 %     whether zero kcat values should be replaced with standard kcat values
    +0049 %     (default true).
    +0050 %
    +0051 % Returns
    +0052 % -------
    +0053 % model : struct
    +0054 %     ecModel where model.ec is expanded with a standard protein with
    +0055 %     standard kcat and standard MW, assigned to reactions without gene
    +0056 %     associations.
    +0057 % rxnsMissingGPR : cell
    +0058 %     a list of updated rxns identifiers with a standard value.
    +0059 % standardMW : double
    +0060 %     the standard MW value calculated.
    +0061 % standardKcat : double
    +0062 %     the standard kcat value calculated.
    +0063 % rxnsNoKcat : cell
    +0064 %     a list of rxns identifiers whose zero kcat has been replaced.
    +0065 %
    +0066 % Notes
    +0067 % -----
    +0068 % While model.ec.kcat is populated, applyKcatConstraints would still need to
    +0069 % be run to apply the new constraints to the S-matrix.
    +0070 %
    +0071 % Examples
    +0072 % --------
    +0073 %     % optional arguments may be given positionally or as name-value pairs:
    +0074 %     [model, rxnsMissingGPR, standardMW, standardKcat, rxnsNoKcat] = getStandardKcat(model);
    +0075 %     [model, rxnsMissingGPR, standardMW, standardKcat, rxnsNoKcat] = getStandardKcat(model, 'threshold', 20);
    +0076 %
    +0077 % See also
    +0078 % --------
    +0079 % removeStandardKcat, applyKcatConstraints
    +0080 
    +0081 p = parseGECKOargs(varargin, { ...
    +0082     'modelAdapter', []; ...
    +0083     'threshold',    []; ...
    +0084     'fillZeroKcat', []});
    +0085 modelAdapter = p.modelAdapter;
    +0086 threshold    = p.threshold;
    +0087 fillZeroKcat = p.fillZeroKcat;
    +0088 
    +0089 if isempty(modelAdapter)
    +0090     modelAdapter = ModelAdapterManager.getDefault();
    +0091     if isempty(modelAdapter)
    +0092         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0093     end
    +0094 end
    +0095 params = modelAdapter.getParameters();
    +0096 
    +0097 if isempty(threshold)
    +0098     threshold = 10;
    +0099 end
    +0100 
    +0101 if isempty(fillZeroKcat)
    +0102     fillZeroKcat = true;
    +0103 end
    +0104 
    +0105 databases = loadDatabases('uniprot', modelAdapter);
    +0106 
    +0107 % An standard MW is defined for all the rxns which does not have a GPR
    +0108 % rule defined. This is based in all the proteins reported for the specific
    +0109 % organism in uniprot
    +0110 standardMW = median(databases.uniprot.MW, 'omitnan');
    +0111 
    +0112 % An standard Kcat is defined for all the rxns which does not have a GPR
    +0113 % rule defined. In this case, the kcat value for a particular reaction is
    +0114 % defined as the median of the kcat values of the reactions (with a real,
    +0115 % nonzero, non-NaN kcat) involved in the same subsystem in which the given
    +0116 % reaction is involved. Nevertheless, if a subSystem have a number of such
    +0117 % reactions lower than a treshold, the kcat value will be the median of the
    +0118 % kcat in all the reactions of the model.
    +0119 
    +0120 % Remove from the list those with kcat zero
    +0121 rxnsKcatZero = model.ec.kcat > 0;
    +0122 
    +0123 % Get the kcat value based on all the kcats in the model
    +0124 standardKcat = median(model.ec.kcat(rxnsKcatZero), 'omitnan');
    +0125 
    +0126 % If the model have subSystems assigned calculate kcat based on subSystem
    +0127 if isfield(model,'subSystems') && ~all(cellfun(@isempty, model.subSystems))
    +0128     standard = false;
    +0129     if model.ec.geckoLight
    +0130         modRxns = extractAfter(model.ec.rxns,4);
    +0131     else
    +0132         modRxns = model.ec.rxns;
    +0133     end
    +0134     % Map ec-rxns to model.rxns
    +0135     [~,rxnIdx]  = ismember(modRxns,model.rxns);
    +0136     % Choose first subSystem
    +0137     enzSubSystems = flattenCell(model.subSystems(rxnIdx));
    +0138     enzSubSystems = enzSubSystems(:,1);
    +0139     if ~all(cellfun(@isempty, enzSubSystems))
    +0140 
    +0141     % Make list of unique subsystems, and which rxns are linked to them
    +0142     [enzSubSystem_names, ~, rxnToSub] = unique(enzSubSystems);
    +0143     % Calculate the median kcat per subSystem, counting only reactions
    +0144     % with a real (nonzero, non-NaN) kcat toward both the median itself
    +0145     % and the threshold that decides whether a subSystem-specific value
    +0146     % is used at all.
    +0147     numSubSystem = numel(enzSubSystem_names);
    +0148     kcatsPerSubSystem = zeros(numSubSystem,1);
    +0149     kcatSubSystem = zeros(numSubSystem,1);
    +0150     for i = 1:numSubSystem
    +0151         subKcat = model.ec.kcat(rxnToSub == i);
    +0152         subKcat = subKcat(subKcat ~= 0 & ~isnan(subKcat));
    +0153         kcatsPerSubSystem(i) = numel(subKcat);
    +0154         if kcatsPerSubSystem(i) >= threshold
    +0155             kcatSubSystem(i) = median(subKcat);
    +0156         else
    +0157             kcatSubSystem(i) = standardKcat;
    +0158         end
    +0159     end
    +0160     else
    +0161         standard = true;
    +0162         printOrange('WARNING: No subSystem-specific kcat values can be calculated');
    +0163     end
    +0164 else
    +0165     standard = true;
    +0166     printOrange('WARNING: No subSystem-specific kcat values can be calculated');
    +0167 end
    +0168 
    +0169 % Find reactions without GPR
    +0170 rxnsMissingGPR = find(cellfun(@isempty, model.grRules));
    +0171 
    +0172 % Find reactions with GPR but without model.ec entry (for instance due to
    +0173 % no protein matching)
    +0174 rxnsMissingEnzyme = find(~cellfun(@isempty, model.grRules));
    +0175 if model.ec.geckoLight
    +0176     ecRxnsList = unique(extractAfter(model.ec.rxns,4));
    +0177 else
    +0178     ecRxnsList = model.ec.rxns;
    +0179 end
    +0180 rxnsMissingEnzyme = find(and(~ismember(model.rxns(rxnsMissingEnzyme),ecRxnsList), ~contains(model.rxns(rxnsMissingEnzyme),'usage_prot_')));
    +0181 rxnsMissingGPR = [rxnsMissingGPR;rxnsMissingEnzyme];
    +0182 
    +0183 % Get custom list of reaction IDs to ignore, if existing. First column
    +0184 % contains reaction IDs, second column contains reaction names for
    +0185 % reference only.
    +0186 if exist(fullfile(params.path,'data','pseudoRxns.tsv'),'file')
    +0187     fID        = fopen(fullfile(params.path,'data','pseudoRxns.tsv'));
    +0188     fileData   = textscan(fID,'%s %s','delimiter','\t');
    +0189     fclose(fID);
    +0190     customRxns = fileData{1};
    +0191     customRxns = find(ismember(model.rxns,customRxns));
    +0192 else
    +0193     customRxns = [];
    +0194 end
    +0195 % Get and remove exchange, transport, spontaneous and pseudo reactions
    +0196 [~, exchangeRxns]  = getExchangeRxns(model);
    +0197 transportRxns = getTransportRxns(model);
    +0198 [spontaneousRxns, ~] = modelAdapter.getSpontaneousReactions(model);
    +0199 pseudoRxns = contains(model.rxnNames,'pseudoreaction');
    +0200 slimeRxns = contains(model.rxnNames,'SLIME rxn');
    +0201 rxnsToIgnore = [customRxns; exchangeRxns; find(transportRxns); ...
    +0202                 find(spontaneousRxns); find(pseudoRxns); find(slimeRxns)];
    +0203 rxnsMissingGPR(ismember(rxnsMissingGPR, rxnsToIgnore)) = [];
    +0204 
    +0205 % Only add if not geckoLight & getStandardKcat was not run earlier
    +0206 if ~any(strcmp(model.mets,'prot_standard'))
    +0207     % Add a new gene to be consistent with ec field named standard
    +0208     proteinStdGenes.genes = 'standard';
    +0209     if isfield(model,'geneShortNames')
    +0210         proteinStdGenes.geneShortNames = 'std';
    +0211     end
    +0212     model = addGenesRaven(model, proteinStdGenes);
    +0213 
    +0214     if ~model.ec.geckoLight
    +0215         % Add a new metabolite named prot_standard
    +0216         proteinStdMets.mets         = 'prot_standard';
    +0217         proteinStdMets.metNames     = proteinStdMets.mets;
    +0218         % Validate compartment
    +0219         compartmentID = strcmp(model.compNames,params.enzyme_comp);
    +0220         if ~any(compartmentID)
    +0221             error(['Compartment ' params.enzyme_comp ' (specified in params.enzyme_comp) '...
    +0222                 'cannot be found in model.compNames'])
    +0223         end
    +0224         proteinStdMets.compartments = model.comps(compartmentID);
    +0225 
    +0226         if isfield(model,'metNotes')
    +0227             proteinStdMets.metNotes = 'Standard enzyme-usage pseudometabolite';
    +0228         end
    +0229         model = addMets(model, proteinStdMets);
    +0230 
    +0231         % Add a protein usage reaction if not a light version
    +0232         proteinStdUsageRxn.rxns         = {'usage_prot_standard'};
    +0233         proteinStdUsageRxn.rxnNames     = proteinStdUsageRxn.rxns;
    +0234         proteinStdUsageRxn.mets         = {proteinStdMets.mets, 'prot_pool'};
    +0235         proteinStdUsageRxn.stoichCoeffs = [1, -1];
    +0236         proteinStdUsageRxn.lb           = 0;
    +0237         proteinStdUsageRxn.ub           = 1000;
    +0238         proteinStdUsageRxn.grRules      = proteinStdGenes.genes;
    +0239 
    +0240         model = addRxns(model, proteinStdUsageRxn);
    +0241     end
    +0242     % Update .ec structure in model
    +0243     model.ec.genes(end+1)      = {'standard'};
    +0244     model.ec.enzymes(end+1)    = {'standard'};
    +0245     model.ec.mw(end+1)         = standardMW;
    +0246     model.ec.sequence(end+1)   = {''};
    +0247     % Additional info
    +0248     if isfield(model.ec,'concs')
    +0249         model.ec.concs(end+1)  = nan();
    +0250     end
    +0251 
    +0252     % Expand the enzyme rxns matrix
    +0253     model.ec.rxnEnzMat =  [model.ec.rxnEnzMat, zeros(length(model.ec.rxns), 1)]; % 1 new enzyme
    +0254     model.ec.rxnEnzMat =  [model.ec.rxnEnzMat; zeros(length(rxnsMissingGPR), length(model.ec.enzymes))]; % new rxns
    +0255 end
    +0256 stdMetIdx = find(strcmpi(model.ec.enzymes, 'standard'));
    +0257 
    +0258 % Remove previous standard kcat assignment
    +0259 oldStandardEnz = find(strcmp(model.ec.source,'standard'));
    +0260 if ~isempty(oldStandardEnz)
    +0261     oldStandardProt = logical(model.ec.rxnEnzMat(oldStandardEnz,stdMetIdx));
    +0262     % If annotated with real enzyme => set kcat to zero
    +0263     model.ec.kcat(oldStandardEnz(~oldStandardProt))        = 0;
    +0264     model.ec.source(oldStandardEnz(~oldStandardProt))      = {''};
    +0265     % If annotated with standard protein => remove entry
    +0266     model.ec.rxns(oldStandardEnz(oldStandardProt))        = [];
    +0267     model.ec.kcat(oldStandardEnz(oldStandardProt))        = [];
    +0268     model.ec.source(oldStandardEnz(oldStandardProt))      = [];
    +0269     model.ec.notes(oldStandardEnz(oldStandardProt))       = [];
    +0270     model.ec.eccodes(oldStandardEnz(oldStandardProt))     = [];
    +0271     model.ec.rxnEnzMat(oldStandardEnz(oldStandardProt),:) = [];
    +0272 end
    +0273 
    +0274 numRxns = length(model.ec.rxns);
    +0275 for i = 1:numel(rxnsMissingGPR)
    +0276     rxnIdx = rxnsMissingGPR(i);
    +0277 
    +0278     % Update .ec structure in model
    +0279     if ~model.ec.geckoLight
    +0280         model.ec.rxns(end+1)     = model.rxns(rxnIdx);
    +0281         % Add prefix in case is light version
    +0282     else
    +0283         model.ec.rxns{end+1}     = ['001_' model.rxns{rxnIdx}];
    +0284     end
    +0285 
    +0286     if ~standard
    +0287         % kcatSubSystemIdx is a one-hot vector (the reaction's first subSystem
    +0288         % matched against every subSystem that has a computed kcat); any(), not
    +0289         % all(), is the right test -- all() only ever succeeds when the model
    +0290         % has exactly one subSystem in total, silently falling back to the
    +0291         % model-wide standardKcat for every reaction otherwise.
    +0292         kcatSubSystemIdx = strcmpi(enzSubSystem_names, model.subSystems{rxnIdx}(1));
    +0293         if any(kcatSubSystemIdx)
    +0294             model.ec.kcat(end+1) = kcatSubSystem(kcatSubSystemIdx);
    +0295         else
    +0296             model.ec.kcat(end+1) = standardKcat;
    +0297         end
    +0298     else
    +0299         model.ec.kcat(end+1) = standardKcat;
    +0300     end
    +0301 
    +0302     model.ec.source(end+1)   = {'standard'};
    +0303     model.ec.notes(end+1)    = {''};
    +0304     model.ec.eccodes(end+1)  = {''};
    +0305 
    +0306     % Update the enzyme rxns matrix
    +0307     model.ec.rxnEnzMat(numRxns+i, stdMetIdx) = 1;
    +0308 end
    +0309 % Get the rxns identifiers of the updated rxns
    +0310 rxnsMissingGPR = model.rxns(rxnsMissingGPR);
    +0311 
    +0312 if fillZeroKcat
    +0313     zeroKcat = model.ec.kcat == 0 | isnan(model.ec.kcat);
    +0314     model.ec.kcat(zeroKcat)     = standardKcat;
    +0315     model.ec.source(zeroKcat)   = {'standard'};
    +0316     rxnsNoKcat = model.ec.rxns(zeroKcat);
    +0317 else
    +0318     rxnsNoKcat = [];
    +0319 end
    +0320 end
    +0321 
    +0322 function Cflat = flattenCell(C,strFlag)
    +0323 %FLATTENCELL  Flatten a nested column cell array into a matrix cell array.
    +0324 %
    +0325 % CFLAT = FLATTENCELL(C) takes a column cell array in which one or more
    +0326 % entries is a nested cell array, and flattens it into a 2D matrix cell
    +0327 % array, where the nested entries are spread across new columns.
    +0328 %
    +0329 % CFLAT = FLATTENCELL(C,STRFLAG) if STRFLAG is TRUE, empty entries in the
    +0330 % resulting CFLAT will be replaced with empty strings {''}. Default = FALSE
    +0331 if nargin < 2
    +0332     strFlag = false;
    +0333 end
    +0334 
    +0335 % determine which entries are cells
    +0336 cells = cellfun(@iscell,C);
    +0337 
    +0338 % determine number of elements in each nested cell
    +0339 cellsizes = cellfun(@numel,C);
    +0340 cellsizes(~cells) = 1;  % ignore non-cell entries
    +0341 
    +0342 % flatten single-entry cells
    +0343 Cflat = C;
    +0344 Cflat(cells & (cellsizes == 1)) = cellfun(@(x) x{1},Cflat(cells & (cellsizes == 1)),'UniformOutput',false);
    +0345 
    +0346 % iterate through multi-entry cells
    +0347 multiCells = find(cellsizes > 1);
    +0348 for i = 1:length(multiCells)
    +0349     cellContents = Cflat{multiCells(i)};
    +0350     Cflat(multiCells(i),1:length(cellContents)) = cellContents;
    +0351 end
    +0352 
    +0353 % change empty elements to strings, if specified
    +0354 if ( strFlag )
    +0355     Cflat(cellfun(@isempty,Cflat)) = {''};
    +0356 end
    +0357 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/index.html b/doc/src/gather_kcats/index.html new file mode 100644 index 00000000..b2b58186 --- /dev/null +++ b/doc/src/gather_kcats/index.html @@ -0,0 +1,29 @@ + + + + Index for Directory src/gather_kcats + + + + + + + + + + +
    < Master indexIndex for src/gather_kcats >
    + +

    Index for src/gather_kcats

    + +

    Matlab files in this directory:

    + +
     assignKcatValuesassignKcatValues Select one kcat value per reaction and write to model.ec.
     assignKcatsassignKcats Assign kcats from the kcat source files and apply them.
     collectKcatscollectKcats Decide one kcat per reaction from the kcat source files.
     convertCustomKcatsconvertCustomKcats Convert data/customKcats.tsv into data/kcats/custom.tsv.
     ecStatsFromBrendaecStatsFromBrenda Summarise loadBRENDAdata's output per EC number, for
     ecTreeEstimateecTreeEstimate EC-tree kcat estimates for EC numbers.
     extractEnzymeSubstratePairsextractEnzymeSubstratePairs The enzyme-substrate pairs of an ecModel's reactions.
     fetchOpenKineticsPredictorfetchOpenKineticsPredictor Fetch and parse an OpenKineticsPredictor job.
     fuzzyKcatMatchingfuzzyKcatMatching Match model EC numbers and substrates to BRENDA kcats.
     getEcRxnKeysgetEcRxnKeys Build-independent keys of the model.ec reactions.
     getStandardKcatgetStandardKcat Assign standard kcat and MW to reactions without enzymes.
     kcatAssignmentConfigkcatAssignmentConfig The kcat assignment settings of a model adapter.
     kcatsFromBrendakcatsFromBrenda Gather kcats from BRENDA and keep them as a source file.
     kcatsFromDLKcatkcatsFromDLKcat Gather kcats from DLKcat and keep them as a source file.
     kcatsFromECTreekcatsFromECTree Estimate kcats from the EC tree and keep them as a source file.
     kcatsFromHomologskcatsFromHomologs Estimate kcats from measured homologs and keep them as a source file.
     kcatsFromOKPkcatsFromOKP Gather kcats from OpenKineticsPredictor and keep them as a source file.
     loadBrendaMeasurementsloadBrendaMeasurements Load the BRENDA measurement table.
     loadKcatSourceloadKcatSource Read a kcat source file and map its rows to an ecModel.
     mergeDLKcatAndFuzzyKcatsmergeDLKcatAndFuzzyKcats Merge DLKcat and BRENDA fuzzy matching results.
     mergeKcatsmergeKcats Merge any number of kcatLists, keeping the highest-priority
     readDLKcatOutputreadDLKcatOutput Read the DLKcat output file into a kcatList structure.
     readOpenKineticsPredictorOutputreadOpenKineticsPredictorOutput Read OpenKineticsPredictor output to kcatList.
     removeStandardKcatremoveStandardKcat Remove the standard pseudoenzyme and standard kcats.
     resolveOkpApiKeyresolveOkpApiKey Resolve the OpenKineticsPredictor API key.
     reviewKcatAssignmentreviewKcatAssignment Flag kcat assignments that deserve a second look.
     runDLKcatrunDLKcat Run DLKcat to predict kcat values from a Docker image.
     saveKcatSourcesaveKcatSource Write a kcatList to a kcat source file of the project.
     submitOpenKineticsPredictorsubmitOpenKineticsPredictor Submit a kcat prediction job to OpenKineticsPredictor.
     updateKcatSourcesupdateKcatSources Gather the kcat sources that the configuration needs.
     writeDLKcatInputwriteDLKcatInput Prepare and write the input file for DLKcat.
     writeOpenKineticsPredictorInputwriteOpenKineticsPredictorInput Write input file for OpenKineticsPredictor.
    + + + + +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/kcatAssignmentConfig.html b/doc/src/gather_kcats/kcatAssignmentConfig.html new file mode 100644 index 00000000..7f3636b9 --- /dev/null +++ b/doc/src/gather_kcats/kcatAssignmentConfig.html @@ -0,0 +1,244 @@ + + + + Description of kcatAssignmentConfig + + + + + + + + + +
    Home > src > gather_kcats > kcatAssignmentConfig.m
    + + + +

    kcatAssignmentConfig +

    + +

    PURPOSE ^

    +
    kcatAssignmentConfig The kcat assignment settings of a model adapter.
    + +

    SYNOPSIS ^

    +
    function config = kcatAssignmentConfig(params)
    + +

    DESCRIPTION ^

    +
     kcatAssignmentConfig  The kcat assignment settings of a model adapter.
    +
    + Reads [kcat_assignment] and [kcat_sources.*] of model_adapter.toml (or
    + params.kcat_assignment and params.kcat_sources of an adapter class), and
    + expands a preset into its stages, as collectKcats and updateKcatSources
    + use them. Without a preset or stages the preset is brenda_ec_tree.
    + geckopy's kcat_assignment_config gives the same settings.
    +
    + Parameters
    + ----------
    + params : struct
    +     the parameters of a model adapter (modelAdapter.params).
    +
    + Returns
    + -------
    + config : struct
    +     - preset: the preset name, or '' when stages are given;
    +     - isozymes, standard: logical;
    +     - stages: struct array with action ('select' or 'combine'), sources
    +       (cell, as given), files (the source files they read, with okp
    +       replaced by the files of its methods), criteria, topOriginLimit,
    +       bottomOriginLimit and wildcardLimit;
    +     - okpMethods: the OKP methods of the okp source group ([kcat_sources.okp]
    +       methods; default all methods with combination parameters);
    +     - sources: per source name its options (from [kcat_sources] and the
    +       preset).
    +
    + Examples
    + --------
    +     config = kcatAssignmentConfig(modelAdapter.params);
    +     config.stages(1).sources   % the order of the sources
    +
    + See also
    + --------
    + collectKcats, assignKcats, updateKcatSources
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • collectKcats collectKcats Decide one kcat per reaction from the kcat source files.
    • updateKcatSources updateKcatSources Gather the kcat sources that the configuration needs.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function config = kcatAssignmentConfig(params)
    +0002 % kcatAssignmentConfig  The kcat assignment settings of a model adapter.
    +0003 %
    +0004 % Reads [kcat_assignment] and [kcat_sources.*] of model_adapter.toml (or
    +0005 % params.kcat_assignment and params.kcat_sources of an adapter class), and
    +0006 % expands a preset into its stages, as collectKcats and updateKcatSources
    +0007 % use them. Without a preset or stages the preset is brenda_ec_tree.
    +0008 % geckopy's kcat_assignment_config gives the same settings.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % params : struct
    +0013 %     the parameters of a model adapter (modelAdapter.params).
    +0014 %
    +0015 % Returns
    +0016 % -------
    +0017 % config : struct
    +0018 %     - preset: the preset name, or '' when stages are given;
    +0019 %     - isozymes, standard: logical;
    +0020 %     - stages: struct array with action ('select' or 'combine'), sources
    +0021 %       (cell, as given), files (the source files they read, with okp
    +0022 %       replaced by the files of its methods), criteria, topOriginLimit,
    +0023 %       bottomOriginLimit and wildcardLimit;
    +0024 %     - okpMethods: the OKP methods of the okp source group ([kcat_sources.okp]
    +0025 %       methods; default all methods with combination parameters);
    +0026 %     - sources: per source name its options (from [kcat_sources] and the
    +0027 %       preset).
    +0028 %
    +0029 % Examples
    +0030 % --------
    +0031 %     config = kcatAssignmentConfig(modelAdapter.params);
    +0032 %     config.stages(1).sources   % the order of the sources
    +0033 %
    +0034 % See also
    +0035 % --------
    +0036 % collectKcats, assignKcats, updateKcatSources
    +0037 
    +0038 a = struct();
    +0039 if isfield(params, 'kcat_assignment') && isstruct(params.kcat_assignment)
    +0040     a = params.kcat_assignment;
    +0041 end
    +0042 config.preset = '';
    +0043 config.isozymes = getOr(a, 'isozymes', true);
    +0044 config.standard = getOr(a, 'standard', true);
    +0045 config.sources = struct();
    +0046 hasPreset = isfield(a, 'preset') && ~isempty(a.preset);
    +0047 hasStages = isfield(a, 'stage') && ~isempty(a.stage);
    +0048 if hasPreset && hasStages
    +0049     error('kcatAssignment:config', ['[kcat_assignment] gives both a preset and stages; ' ...
    +0050         'give one of the two.'])
    +0051 end
    +0052 if hasStages
    +0053     config.stages = arrayfun(@readStage, a.stage(:)');
    +0054 else
    +0055     preset = 'brenda_ec_tree';
    +0056     if hasPreset
    +0057         preset = char(a.preset);
    +0058     end
    +0059     [config.stages, config.sources] = presetStages(preset);
    +0060     config.preset = preset;
    +0061 end
    +0062 if isfield(params, 'kcat_sources') && isstruct(params.kcat_sources)
    +0063     names = fieldnames(params.kcat_sources);
    +0064     for k = 1:numel(names)
    +0065         config.sources.(names{k}) = params.kcat_sources.(names{k});
    +0066     end
    +0067 end
    +0068 % The okp group: the OKP methods of [kcat_sources.okp] methods.
    +0069 known = {'CataPro','CatPred','CatRange','DLKcat','EITLEM','KinForm-H','KinForm-L', ...
    +0070     'OmniESI','OmniESI-O2DENet','TurNup','UniKP'};
    +0071 % The default: methods that read enzyme-substrate pairs and have combination
    +0072 % parameters (CatRange predicts classes; CatPred and TurNup read whole
    +0073 % reactions, which kcatsFromOKP does not submit).
    +0074 config.okpMethods = known(~ismember(known, {'CatRange', 'CatPred', 'TurNup'}));
    +0075 if isfield(config.sources, 'okp') && isfield(config.sources.okp, 'methods') && ~isempty(config.sources.okp.methods)
    +0076     config.okpMethods = cellstr(config.sources.okp.methods);
    +0077     config.okpMethods = config.okpMethods(:)';
    +0078 end
    +0079 unknown = setdiff(config.okpMethods, known);
    +0080 if ~isempty(unknown)
    +0081     error('kcatAssignment:config', 'Unknown OKP methods in [kcat_sources.okp] methods: %s; methods: %s.', ...
    +0082         strjoin(unknown, ', '), strjoin(known, ', '))
    +0083 end
    +0084 okpFiles = cellfun(@(m) ['okp_' lower(regexprep(regexprep(m, '[^A-Za-z0-9]+', '_'), '^_+|_+$', ''))], ...
    +0085     config.okpMethods, 'UniformOutput', false);
    +0086 for s = 1:numel(config.stages)
    +0087     files = {};
    +0088     for t = config.stages(s).sources
    +0089         if strcmp(t{1}, 'okp')
    +0090             files = [files, okpFiles]; %#ok<AGROW>
    +0091         else
    +0092             files{end+1} = t{1}; %#ok<AGROW>
    +0093         end
    +0094     end
    +0095     [~, first] = unique(files, 'stable');
    +0096     config.stages(s).files = files(sort(first));
    +0097 end
    +0098 end
    +0099 
    +0100 function [stages, sources] = presetStages(preset)
    +0101 % The presets of kcat assignment; geckopy defines the same.
    +0102 stage = @(action, srcs, top) struct('action', action, 'sources', {srcs}, 'criteria', 'max', ...
    +0103     'topOriginLimit', top, 'bottomOriginLimit', 6, 'wildcardLimit', 3);
    +0104 order = {'custom', 'database_top', 'dlkcat', 'database_bottom'};
    +0105 own = {'custom', 'database_top'}; % with topOriginLimit 1: the organism's own BRENDA value
    +0106 sources = struct();
    +0107 switch preset
    +0108     case 'brenda_ec_tree'
    +0109         stages = [stage('select', [own, {'ec_tree'}], 1), stage('combine', {'okp'}, 4)];
    +0110         sources.brenda = struct('aggregation', 'median');
    +0111         sources.ec_tree = struct('k', 5);
    +0112     case 'ec_tree_homologs'
    +0113         stages = [stage('select', own, 1), stage('combine', {'ec_tree', 'homologs'}, 4), ...
    +0114             stage('combine', {'okp'}, 4)];
    +0115         sources.brenda = struct('aggregation', 'median');
    +0116         sources.ec_tree = struct('k', 5);
    +0117     case 'ec_tree_okp'
    +0118         stages = [stage('select', own, 1), stage('combine', {'ec_tree', 'homologs', 'okp'}, 4), ...
    +0119             stage('combine', {'okp'}, 4)];
    +0120         sources.brenda = struct('aggregation', 'median');
    +0121         sources.ec_tree = struct('k', 5);
    +0122     case 'okp'
    +0123         stages = [stage('select', {'custom'}, 4), stage('combine', {'okp'}, 4)];
    +0124     case 'gecko_median'
    +0125         stages = stage('select', order, 4);
    +0126         sources.brenda = struct('aggregation', 'median');
    +0127     case 'gecko_classic'
    +0128         stages = stage('select', order, 6);
    +0129         sources.brenda = struct('aggregation', 'max');
    +0130     otherwise
    +0131         error('kcatAssignment:config', 'Unknown kcat assignment preset "%s". Presets: %s.', ...
    +0132             preset, 'brenda_ec_tree, ec_tree_homologs, ec_tree_okp, okp, gecko_median, gecko_classic')
    +0133 end
    +0134 end
    +0135 
    +0136 function stage = readStage(s)
    +0137 stage.action = getOr(s, 'action', 'select');
    +0138 if ~any(strcmp(stage.action, {'select', 'combine'}))
    +0139     error('kcatAssignment:config', ['Unknown stage action "%s"; this GECKO version knows ' ...
    +0140         '"select" and "combine".'], stage.action)
    +0141 end
    +0142 sources = getOr(s, 'sources', {});
    +0143 if ischar(sources)
    +0144     sources = {sources};
    +0145 end
    +0146 if isempty(sources)
    +0147     error('kcatAssignment:config', 'A [[kcat_assignment.stage]] needs sources.')
    +0148 end
    +0149 stage.sources = sources(:)';
    +0150 stage.criteria = validatestring(getOr(s, 'criteria', 'max'), {'max','min','median','mean'});
    +0151 stage.topOriginLimit = getOr(s, 'top_origin_limit', 4);
    +0152 stage.bottomOriginLimit = getOr(s, 'bottom_origin_limit', 6);
    +0153 stage.wildcardLimit = getOr(s, 'wildcard_limit', 3);
    +0154 end
    +0155 
    +0156 function v = getOr(s, field, default)
    +0157 v = default;
    +0158 if isstruct(s) && isfield(s, field) && ~isempty(s.(field))
    +0159     v = s.(field);
    +0160 end
    +0161 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/kcatsFromBrenda.html b/doc/src/gather_kcats/kcatsFromBrenda.html new file mode 100644 index 00000000..20aead8a --- /dev/null +++ b/doc/src/gather_kcats/kcatsFromBrenda.html @@ -0,0 +1,243 @@ + + + + Description of kcatsFromBrenda + + + + + + + + + +
    Home > src > gather_kcats > kcatsFromBrenda.m
    + + + +

    kcatsFromBrenda +

    + +

    PURPOSE ^

    +
    kcatsFromBrenda Gather kcats from BRENDA and keep them as a source file.
    + +

    SYNOPSIS ^

    +
    function kcatList = kcatsFromBrenda(model, varargin)
    + +

    DESCRIPTION ^

    +
     kcatsFromBrenda  Gather kcats from BRENDA and keep them as a source file.
    +
    + Matches the model's EC numbers and substrates to BRENDA by fuzzy
    + matching (see fuzzyKcatMatching), and writes the result to
    + data/kcats/brenda.tsv in the project folder (see saveKcatSource). The
    + matching runs locally on the BRENDA files of GECKO.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure), with EC
    +     numbers (getECfromDatabase or getECfromGEM).
    +
    + Name-Value Arguments
    + --------------------
    + aggregation : char
    +     which BRENDA value per EC number, substrate and organism is used:
    +     'max' or 'median' (default: params.kcatAggregation of the model
    +     adapter, or 'max').
    + forceWClvl : double
    +     number of extra levels, from the right, replaced by a wildcard in the
    +     EC numbers (on top of any wildcard already in the code; default 0).
    + ecRxns : logical or double
    +     for which model.ec.rxns kcats are gathered (default: all). A logical
    +     vector or indices of model.ec.rxns, see fuzzyKcatMatching; [] selects
    +     all reactions and any other empty selection is an error.
    + save : logical
    +     write the source file (default true).
    + saveAs : char
    +     name of the source file, without .tsv (default 'brenda'). With
    +     ecRxns, the file then only holds those reactions.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + kcatList : struct
    +     the kcat values, as returned by fuzzyKcatMatching.
    +
    + Examples
    + --------
    +     kcatsFromBrenda(ecModel);
    +     kcatList = kcatsFromBrenda(ecModel, 'aggregation', 'median');
    +
    + See also
    + --------
    + fuzzyKcatMatching, kcatsFromDLKcat, kcatsFromOKP, saveKcatSource, loadKcatSource
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • fuzzyKcatMatching fuzzyKcatMatching Match model EC numbers and substrates to BRENDA kcats.
    • saveKcatSource saveKcatSource Write a kcatList to a kcat source file of the project.
    +This function is called by: +
      +
    • updateKcatSources updateKcatSources Gather the kcat sources that the configuration needs.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function kcatList = kcatsFromBrenda(model, varargin)
    +0002 % kcatsFromBrenda  Gather kcats from BRENDA and keep them as a source file.
    +0003 %
    +0004 % Matches the model's EC numbers and substrates to BRENDA by fuzzy
    +0005 % matching (see fuzzyKcatMatching), and writes the result to
    +0006 % data/kcats/brenda.tsv in the project folder (see saveKcatSource). The
    +0007 % matching runs locally on the BRENDA files of GECKO.
    +0008 %
    +0009 % Parameters
    +0010 % ----------
    +0011 % model : struct
    +0012 %     an ecModel in GECKO 3 format (with ecModel.ec structure), with EC
    +0013 %     numbers (getECfromDatabase or getECfromGEM).
    +0014 %
    +0015 % Name-Value Arguments
    +0016 % --------------------
    +0017 % aggregation : char
    +0018 %     which BRENDA value per EC number, substrate and organism is used:
    +0019 %     'max' or 'median' (default: params.kcatAggregation of the model
    +0020 %     adapter, or 'max').
    +0021 % forceWClvl : double
    +0022 %     number of extra levels, from the right, replaced by a wildcard in the
    +0023 %     EC numbers (on top of any wildcard already in the code; default 0).
    +0024 % ecRxns : logical or double
    +0025 %     for which model.ec.rxns kcats are gathered (default: all). A logical
    +0026 %     vector or indices of model.ec.rxns, see fuzzyKcatMatching; [] selects
    +0027 %     all reactions and any other empty selection is an error.
    +0028 % save : logical
    +0029 %     write the source file (default true).
    +0030 % saveAs : char
    +0031 %     name of the source file, without .tsv (default 'brenda'). With
    +0032 %     ecRxns, the file then only holds those reactions.
    +0033 % modelAdapter : ModelAdapter
    +0034 %     a loaded model adapter (default: the current default model adapter).
    +0035 %
    +0036 % Returns
    +0037 % -------
    +0038 % kcatList : struct
    +0039 %     the kcat values, as returned by fuzzyKcatMatching.
    +0040 %
    +0041 % Examples
    +0042 % --------
    +0043 %     kcatsFromBrenda(ecModel);
    +0044 %     kcatList = kcatsFromBrenda(ecModel, 'aggregation', 'median');
    +0045 %
    +0046 % See also
    +0047 % --------
    +0048 % fuzzyKcatMatching, kcatsFromDLKcat, kcatsFromOKP, saveKcatSource, loadKcatSource
    +0049 
    +0050 checkOptions(varargin, {'aggregation','forceWClvl','ecRxns','save','saveAs','modelAdapter'}, 'kcatsFromBrenda');
    +0051 p = parseGECKOargs(varargin, { ...
    +0052     'aggregation',  []; ...
    +0053     'forceWClvl',   0; ...
    +0054     'ecRxns',       []; ...
    +0055     'save',         true; ...
    +0056     'saveAs',       'brenda'; ...
    +0057     'modelAdapter', []});
    +0058 modelAdapter = p.modelAdapter;
    +0059 if isempty(modelAdapter)
    +0060     modelAdapter = ModelAdapterManager.getDefault();
    +0061     if isempty(modelAdapter)
    +0062         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0063     end
    +0064 end
    +0065 aggregation = resolveKcatAggregation(p.aggregation, modelAdapter);
    +0066 if isSubset(p.ecRxns) && countSelected(p.ecRxns) == 0
    +0067     error('kcatsFromBrenda:emptySubset', ...
    +0068         'ecRxns selects no reactions; leave it out to gather for all reactions.');
    +0069 end
    +0070 if p.save
    +0071     file = fullfile(modelAdapter.params.path, 'data', 'kcats', [char(p.saveAs) '.tsv']);
    +0072     warnSubset(p.ecRxns, numel(model.ec.rxns), file);
    +0073 end
    +0074 
    +0075 kcatList = fuzzyKcatMatching(model, 'ecRxns', p.ecRxns, 'modelAdapter', modelAdapter, ...
    +0076     'forceWClvl', p.forceWClvl, 'kcatAggregation', aggregation);
    +0077 
    +0078 if p.save
    +0079     parameters = struct('aggregation', aggregation, 'force_wildcard_level', p.forceWClvl);
    +0080     if isSubset(p.ecRxns)
    +0081         parameters.ec_rxns = numel(kcatList.rxns);
    +0082     end
    +0083     saveKcatSource(model, kcatList, p.saveAs, 'modelAdapter', modelAdapter, ...
    +0084         'generator', 'kcatsFromBrenda', 'parameters', parameters, ...
    +0085         'data', brendaRelease(modelAdapter));
    +0086     fprintf('BRENDA kcats for %d reactions written to %s\n', sum(kcatList.kcats > 0), file);
    +0087 end
    +0088 end
    +0089 
    +0090 function release = brendaRelease(modelAdapter)
    +0091 % The release line at the top of kcat.tsv, e.g. 'BRENDA release 2026.1'.
    +0092 release = '';
    +0093 file = fullfile(modelAdapter.getBrendaDBFolder(), 'kcat.tsv');
    +0094 fid = fopen(file, 'r');
    +0095 if fid < 0
    +0096     return
    +0097 end
    +0098 line = fgetl(fid);
    +0099 fclose(fid);
    +0100 tok = regexp(line, '^#\s*(BRENDA release [^ ]+)', 'tokens', 'once');
    +0101 if ~isempty(tok)
    +0102     release = tok{1};
    +0103 end
    +0104 end
    +0105 
    +0106 function tf = isSubset(ecRxns)
    +0107 % [] selects all reactions; any other value selects the reactions it names.
    +0108 tf = ~(isnumeric(ecRxns) && isequal(size(ecRxns),[0 0]));
    +0109 end
    +0110 
    +0111 function n = countSelected(ecRxns)
    +0112 if islogical(ecRxns)
    +0113     n = sum(ecRxns);
    +0114 else
    +0115     n = numel(ecRxns);
    +0116 end
    +0117 end
    +0118 
    +0119 function n = countRxns(ecRxns)
    +0120 if islogical(ecRxns)
    +0121     n = sum(ecRxns);
    +0122 else
    +0123     n = numel(unique(ecRxns));
    +0124 end
    +0125 end
    +0126 
    +0127 function warnSubset(ecRxns, nRxns, file)
    +0128 % A subset written under the default name replaces the full file.
    +0129 if isSubset(ecRxns) && countRxns(ecRxns) < nRxns && isfile(file)
    +0130     printOrange(sprintf(['%s is replaced by kcats for %d reactions only. Give saveAs ' ...
    +0131         'to keep it.\n'], file, countRxns(ecRxns)));
    +0132 end
    +0133 end
    +0134 
    +0135 function checkOptions(args, names, functionName)
    +0136 % Options are name-value pairs with known names, so a misspelled option is
    +0137 % an error instead of being taken as a positional argument.
    +0138 id = [functionName ':arguments'];
    +0139 given = args(1:2:end);
    +0140 if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given))
    +0141     error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', '))
    +0142 end
    +0143 unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names);
    +0144 if ~isempty(unknown)
    +0145     error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ...
    +0146         strjoin(names, ', '))
    +0147 end
    +0148 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/kcatsFromDLKcat.html b/doc/src/gather_kcats/kcatsFromDLKcat.html new file mode 100644 index 00000000..81610980 --- /dev/null +++ b/doc/src/gather_kcats/kcatsFromDLKcat.html @@ -0,0 +1,237 @@ + + + + Description of kcatsFromDLKcat + + + + + + + + + +
    Home > src > gather_kcats > kcatsFromDLKcat.m
    + + + +

    kcatsFromDLKcat +

    + +

    PURPOSE ^

    +
    kcatsFromDLKcat Gather kcats from DLKcat and keep them as a source file.
    + +

    SYNOPSIS ^

    +
    function kcatList = kcatsFromDLKcat(model, varargin)
    + +

    DESCRIPTION ^

    +
     kcatsFromDLKcat  Gather kcats from DLKcat and keep them as a source file.
    +
    + Predicts kcats with DLKcat and writes them to data/kcats/dlkcat.tsv in
    + the project folder (see saveKcatSource). With 'run', true it writes the
    + DLKcat input (writeDLKcatInput) and runs DLKcat through its Docker image
    + (runDLKcat), which needs Docker; otherwise it reads the output of an
    + earlier run (readDLKcatOutput). A run records how many reactions it
    + covered in data/DLKcat_run.txt, so that the source file says so also when
    + the output is read later.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure), with
    +     metabolite SMILES (findMetSmiles) and protein sequences.
    +
    + Name-Value Arguments
    + --------------------
    + run : logical
    +     write the input and run DLKcat; false reads the existing output in
    +     data/DLKcat.tsv (default false).
    + ecRxns : logical
    +     for which model.ec.rxns DLKcat is run (default: all). Only used with
    +     'run', true.
    + save : logical
    +     write the source file (default true).
    + saveAs : char
    +     name of the source file, without .tsv (default 'dlkcat').
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + kcatList : struct
    +     the kcat values, as returned by readDLKcatOutput.
    +
    + Examples
    + --------
    +     kcatsFromDLKcat(ecModel, 'run', true);
    +     kcatList = kcatsFromDLKcat(ecModel);
    +
    + See also
    + --------
    + writeDLKcatInput, runDLKcat, readDLKcatOutput, kcatsFromBrenda, saveKcatSource
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • readDLKcatOutput readDLKcatOutput Read the DLKcat output file into a kcatList structure.
    • runDLKcat runDLKcat Run DLKcat to predict kcat values from a Docker image.
    • saveKcatSource saveKcatSource Write a kcatList to a kcat source file of the project.
    • writeDLKcatInput writeDLKcatInput Prepare and write the input file for DLKcat.
    +This function is called by: +
      +
    • updateKcatSources updateKcatSources Gather the kcat sources that the configuration needs.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function kcatList = kcatsFromDLKcat(model, varargin)
    +0002 % kcatsFromDLKcat  Gather kcats from DLKcat and keep them as a source file.
    +0003 %
    +0004 % Predicts kcats with DLKcat and writes them to data/kcats/dlkcat.tsv in
    +0005 % the project folder (see saveKcatSource). With 'run', true it writes the
    +0006 % DLKcat input (writeDLKcatInput) and runs DLKcat through its Docker image
    +0007 % (runDLKcat), which needs Docker; otherwise it reads the output of an
    +0008 % earlier run (readDLKcatOutput). A run records how many reactions it
    +0009 % covered in data/DLKcat_run.txt, so that the source file says so also when
    +0010 % the output is read later.
    +0011 %
    +0012 % Parameters
    +0013 % ----------
    +0014 % model : struct
    +0015 %     an ecModel in GECKO 3 format (with ecModel.ec structure), with
    +0016 %     metabolite SMILES (findMetSmiles) and protein sequences.
    +0017 %
    +0018 % Name-Value Arguments
    +0019 % --------------------
    +0020 % run : logical
    +0021 %     write the input and run DLKcat; false reads the existing output in
    +0022 %     data/DLKcat.tsv (default false).
    +0023 % ecRxns : logical
    +0024 %     for which model.ec.rxns DLKcat is run (default: all). Only used with
    +0025 %     'run', true.
    +0026 % save : logical
    +0027 %     write the source file (default true).
    +0028 % saveAs : char
    +0029 %     name of the source file, without .tsv (default 'dlkcat').
    +0030 % modelAdapter : ModelAdapter
    +0031 %     a loaded model adapter (default: the current default model adapter).
    +0032 %
    +0033 % Returns
    +0034 % -------
    +0035 % kcatList : struct
    +0036 %     the kcat values, as returned by readDLKcatOutput.
    +0037 %
    +0038 % Examples
    +0039 % --------
    +0040 %     kcatsFromDLKcat(ecModel, 'run', true);
    +0041 %     kcatList = kcatsFromDLKcat(ecModel);
    +0042 %
    +0043 % See also
    +0044 % --------
    +0045 % writeDLKcatInput, runDLKcat, readDLKcatOutput, kcatsFromBrenda, saveKcatSource
    +0046 
    +0047 checkOptions(varargin, {'run','ecRxns','save','saveAs','modelAdapter'}, 'kcatsFromDLKcat');
    +0048 p = parseGECKOargs(varargin, { ...
    +0049     'run',          false; ...
    +0050     'ecRxns',       []; ...
    +0051     'save',         true; ...
    +0052     'saveAs',       'dlkcat'; ...
    +0053     'modelAdapter', []});
    +0054 modelAdapter = p.modelAdapter;
    +0055 if isempty(modelAdapter)
    +0056     modelAdapter = ModelAdapterManager.getDefault();
    +0057     if isempty(modelAdapter)
    +0058         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0059     end
    +0060 end
    +0061 if ~p.run && ~isempty(p.ecRxns)
    +0062     error('kcatsFromDLKcat:ecRxns', ['ecRxns selects the reactions DLKcat is run for, so ' ...
    +0063         'it needs ''run'', true.'])
    +0064 end
    +0065 if p.save
    +0066     file = fullfile(modelAdapter.params.path, 'data', 'kcats', [char(p.saveAs) '.tsv']);
    +0067     if p.run
    +0068         warnSubset(p.ecRxns, numel(model.ec.rxns), file);
    +0069     end
    +0070 end
    +0071 
    +0072 runFile = fullfile(modelAdapter.params.path, 'data', 'DLKcat_run.txt');
    +0073 if p.run
    +0074     % As runDLKcat: on macOS, MATLAB started from the launcher may not
    +0075     % have Docker on its path.
    +0076     if ismac
    +0077         setenv('PATH', strcat('/usr/local/bin', ':', getenv("PATH")));
    +0078     end
    +0079     [status, ~] = system('docker --version');
    +0080     if status ~= 0
    +0081         error('kcatsFromDLKcat:noDocker', ['DLKcat runs in a Docker image, but Docker was ' ...
    +0082             'not found. Install it from https://www.docker.com, or call kcatsFromDLKcat ' ...
    +0083             'without ''run'' to read an earlier DLKcat output.'])
    +0084     end
    +0085     writeDLKcatInput(model, 'ecRxns', p.ecRxns, 'modelAdapter', modelAdapter, 'overwrite', true);
    +0086     runDLKcat('modelAdapter', modelAdapter);
    +0087     fid = fopen(runFile, 'w');
    +0088     if ~isempty(p.ecRxns)
    +0089         fprintf(fid, 'ecRxns: %d\n', countRxns(p.ecRxns));
    +0090     end
    +0091     fclose(fid);
    +0092 else
    +0093     outFile = fullfile(modelAdapter.params.path, 'data', 'DLKcat.tsv');
    +0094     if ~isfile(outFile)
    +0095         error('kcatsFromDLKcat:noOutput', ['No DLKcat output at %s. Run ' ...
    +0096             'kcatsFromDLKcat(model, ''run'', true) first.'], outFile)
    +0097     end
    +0098 end
    +0099 kcatList = readDLKcatOutput(model, 'modelAdapter', modelAdapter);
    +0100 
    +0101 if p.save
    +0102     parameters = struct('run', logical(p.run));
    +0103     if isfile(runFile)
    +0104         tok = regexp(fileread(runFile), 'ecRxns:\s*(\d+)', 'tokens', 'once');
    +0105         if ~isempty(tok)
    +0106             parameters.ec_rxns = str2double(tok{1});
    +0107         end
    +0108     end
    +0109     saveKcatSource(model, kcatList, p.saveAs, 'modelAdapter', modelAdapter, ...
    +0110         'generator', 'kcatsFromDLKcat', 'parameters', parameters);
    +0111     fprintf('DLKcat kcats for %d reactions written to %s\n', ...
    +0112         numel(unique(kcatList.rxns(kcatList.kcats > 0))), file);
    +0113 end
    +0114 end
    +0115 
    +0116 function n = countRxns(ecRxns)
    +0117 if islogical(ecRxns)
    +0118     n = sum(ecRxns);
    +0119 else
    +0120     n = numel(unique(ecRxns));
    +0121 end
    +0122 end
    +0123 
    +0124 function warnSubset(ecRxns, nRxns, file)
    +0125 % A subset written under the default name replaces the full file.
    +0126 if ~isempty(ecRxns) && countRxns(ecRxns) < nRxns && isfile(file)
    +0127     printOrange(sprintf(['%s is replaced by kcats for %d reactions only. Give saveAs ' ...
    +0128         'to keep it.\n'], file, countRxns(ecRxns)));
    +0129 end
    +0130 end
    +0131 
    +0132 function checkOptions(args, names, functionName)
    +0133 % Options are name-value pairs with known names, so a misspelled option is
    +0134 % an error instead of being taken as a positional argument.
    +0135 id = [functionName ':arguments'];
    +0136 given = args(1:2:end);
    +0137 if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given))
    +0138     error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', '))
    +0139 end
    +0140 unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names);
    +0141 if ~isempty(unknown)
    +0142     error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ...
    +0143         strjoin(names, ', '))
    +0144 end
    +0145 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/kcatsFromECTree.html b/doc/src/gather_kcats/kcatsFromECTree.html new file mode 100644 index 00000000..33a11e70 --- /dev/null +++ b/doc/src/gather_kcats/kcatsFromECTree.html @@ -0,0 +1,234 @@ + + + + Description of kcatsFromECTree + + + + + + + + + +
    Home > src > gather_kcats > kcatsFromECTree.m
    + + + +

    kcatsFromECTree +

    + +

    PURPOSE ^

    +
    kcatsFromECTree Estimate kcats from the EC tree and keep them as a source file.
    + +

    SYNOPSIS ^

    +
    function kcatList = kcatsFromECTree(model, varargin)
    + +

    DESCRIPTION ^

    +
     kcatsFromECTree  Estimate kcats from the EC tree and keep them as a source file.
    +
    + Each reaction gets the median kcat of all wild-type BRENDA measurements
    + of its EC number, from any organism and substrate, shrunk toward the
    + median of the EC's 3-digit and 2-digit classes with weight n / (n + k)
    + for n measurements (see ecTreeEstimate). A reaction with several EC
    + numbers uses the one with most measurements. Reactions without an EC
    + number, or whose EC classes have no measurements, get no value. The
    + result is written to data/kcats/ec_tree.tsv in the project folder (see
    + saveKcatSource).
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure), with EC
    +     numbers (getECfromDatabase or getECfromGEM).
    +
    + Name-Value Arguments
    + --------------------
    + k : double
    +     shrinkage constant (default 5): the number of measurements at which
    +     an EC's own median and its class count equally.
    + ecRxns : logical
    +     for which model.ec.rxns kcats are estimated (default: all).
    + measurements : struct
    +     BRENDA measurement table (default: loadBrendaMeasurements with the
    +     model adapter).
    + save : logical
    +     write the source file (default true).
    + saveAs : char
    +     name of the source file, without .tsv (default 'ec_tree'). With
    +     ecRxns, the file then only holds those reactions.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + kcatList : struct
    +     the kcat values, with fields source, rxns, eccodes, kcats and detail
    +     (the number of measurements of the EC, n, and the deepest EC level
    +     with measurements, depth).
    +
    + Examples
    + --------
    +     kcatsFromECTree(ecModel);
    +     kcatList = kcatsFromECTree(ecModel, 'k', 10, 'save', false);
    +
    + See also
    + --------
    + ecTreeEstimate, loadBrendaMeasurements, kcatsFromBrenda, saveKcatSource, assignKcats
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: + +This function is called by: +
      +
    • updateKcatSources updateKcatSources Gather the kcat sources that the configuration needs.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function kcatList = kcatsFromECTree(model, varargin)
    +0002 % kcatsFromECTree  Estimate kcats from the EC tree and keep them as a source file.
    +0003 %
    +0004 % Each reaction gets the median kcat of all wild-type BRENDA measurements
    +0005 % of its EC number, from any organism and substrate, shrunk toward the
    +0006 % median of the EC's 3-digit and 2-digit classes with weight n / (n + k)
    +0007 % for n measurements (see ecTreeEstimate). A reaction with several EC
    +0008 % numbers uses the one with most measurements. Reactions without an EC
    +0009 % number, or whose EC classes have no measurements, get no value. The
    +0010 % result is written to data/kcats/ec_tree.tsv in the project folder (see
    +0011 % saveKcatSource).
    +0012 %
    +0013 % Parameters
    +0014 % ----------
    +0015 % model : struct
    +0016 %     an ecModel in GECKO 3 format (with ecModel.ec structure), with EC
    +0017 %     numbers (getECfromDatabase or getECfromGEM).
    +0018 %
    +0019 % Name-Value Arguments
    +0020 % --------------------
    +0021 % k : double
    +0022 %     shrinkage constant (default 5): the number of measurements at which
    +0023 %     an EC's own median and its class count equally.
    +0024 % ecRxns : logical
    +0025 %     for which model.ec.rxns kcats are estimated (default: all).
    +0026 % measurements : struct
    +0027 %     BRENDA measurement table (default: loadBrendaMeasurements with the
    +0028 %     model adapter).
    +0029 % save : logical
    +0030 %     write the source file (default true).
    +0031 % saveAs : char
    +0032 %     name of the source file, without .tsv (default 'ec_tree'). With
    +0033 %     ecRxns, the file then only holds those reactions.
    +0034 % modelAdapter : ModelAdapter
    +0035 %     a loaded model adapter (default: the current default model adapter).
    +0036 %
    +0037 % Returns
    +0038 % -------
    +0039 % kcatList : struct
    +0040 %     the kcat values, with fields source, rxns, eccodes, kcats and detail
    +0041 %     (the number of measurements of the EC, n, and the deepest EC level
    +0042 %     with measurements, depth).
    +0043 %
    +0044 % Examples
    +0045 % --------
    +0046 %     kcatsFromECTree(ecModel);
    +0047 %     kcatList = kcatsFromECTree(ecModel, 'k', 10, 'save', false);
    +0048 %
    +0049 % See also
    +0050 % --------
    +0051 % ecTreeEstimate, loadBrendaMeasurements, kcatsFromBrenda, saveKcatSource, assignKcats
    +0052 
    +0053 checkOptions(varargin, {'k','ecRxns','measurements','save','saveAs','modelAdapter'}, 'kcatsFromECTree');
    +0054 p = parseGECKOargs(varargin, { ...
    +0055     'k',            5; ...
    +0056     'ecRxns',       []; ...
    +0057     'measurements', []; ...
    +0058     'save',         true; ...
    +0059     'saveAs',       'ec_tree'; ...
    +0060     'modelAdapter', []});
    +0061 modelAdapter = p.modelAdapter;
    +0062 if isempty(modelAdapter)
    +0063     modelAdapter = ModelAdapterManager.getDefault();
    +0064     if isempty(modelAdapter)
    +0065         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0066     end
    +0067 end
    +0068 if ~isfield(model.ec, 'eccodes')
    +0069     error('No EC codes defined in model.ec.eccodes. First run getECfromGEM() and/or getECfromDatabase().')
    +0070 end
    +0071 if p.save
    +0072     file = fullfile(modelAdapter.params.path, 'data', 'kcats', [char(p.saveAs) '.tsv']);
    +0073     warnSubset(p.ecRxns, numel(model.ec.rxns), file);
    +0074 end
    +0075 measurements = p.measurements;
    +0076 if isempty(measurements)
    +0077     measurements = loadBrendaMeasurements('modelAdapter', modelAdapter);
    +0078 end
    +0079 
    +0080 idx = (1:numel(model.ec.rxns))';
    +0081 if ~isempty(p.ecRxns)
    +0082     idx = idx(p.ecRxns(:));
    +0083 end
    +0084 eccodes = model.ec.eccodes(idx);
    +0085 eccodes(cellfun(@(e) ~ischar(e) && ~isstring(e), eccodes)) = {''};
    +0086 [values, n, depth, ecUsed] = ecTreeEstimate(eccodes, measurements, p.k);
    +0087 found = depth > 0;
    +0088 idx = idx(found);
    +0089 kcatList.source  = 'ec_tree';
    +0090 kcatList.rxns    = model.ec.rxns(idx);
    +0091 kcatList.eccodes = ecUsed(found);
    +0092 kcatList.kcats   = 10 .^ values(found);
    +0093 kcatList.detail  = cellstr("n=" + string(n(found)) + "; depth=" + string(depth(found)));
    +0094 
    +0095 if p.save
    +0096     parameters = struct('k', p.k);
    +0097     if ~isempty(p.ecRxns)
    +0098         parameters.ec_rxns = countRxns(p.ecRxns);
    +0099     end
    +0100     saveKcatSource(model, kcatList, p.saveAs, 'modelAdapter', modelAdapter, ...
    +0101         'generator', 'kcatsFromECTree', 'parameters', parameters, ...
    +0102         'data', measurements.release);
    +0103     fprintf('EC-tree kcats for %d reactions written to %s\n', numel(kcatList.rxns), file);
    +0104 end
    +0105 end
    +0106 
    +0107 function n = countRxns(ecRxns)
    +0108 if islogical(ecRxns)
    +0109     n = sum(ecRxns);
    +0110 else
    +0111     n = numel(unique(ecRxns));
    +0112 end
    +0113 end
    +0114 
    +0115 function warnSubset(ecRxns, nRxns, file)
    +0116 % A subset written under the default name replaces the full file.
    +0117 if ~isempty(ecRxns) && countRxns(ecRxns) < nRxns && isfile(file)
    +0118     printOrange(sprintf(['%s is replaced by kcats for %d reactions only. Give saveAs ' ...
    +0119         'to keep it.\n'], file, countRxns(ecRxns)));
    +0120 end
    +0121 end
    +0122 
    +0123 function checkOptions(args, names, functionName)
    +0124 % Options are name-value pairs with known names, so a misspelled option is
    +0125 % an error instead of being taken as a positional argument.
    +0126 id = [functionName ':arguments'];
    +0127 given = args(1:2:end);
    +0128 if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given))
    +0129     error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', '))
    +0130 end
    +0131 unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names);
    +0132 if ~isempty(unknown)
    +0133     error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ...
    +0134         strjoin(names, ', '))
    +0135 end
    +0136 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/kcatsFromHomologs.html b/doc/src/gather_kcats/kcatsFromHomologs.html new file mode 100644 index 00000000..2e1bc272 --- /dev/null +++ b/doc/src/gather_kcats/kcatsFromHomologs.html @@ -0,0 +1,403 @@ + + + + Description of kcatsFromHomologs + + + + + + + + + +
    Home > src > gather_kcats > kcatsFromHomologs.m
    + + + +

    kcatsFromHomologs +

    + +

    PURPOSE ^

    +
    kcatsFromHomologs Estimate kcats from measured homologs and keep them as a source file.
    + +

    SYNOPSIS ^

    +
    function kcatList = kcatsFromHomologs(model, varargin)
    + +

    DESCRIPTION ^

    +
     kcatsFromHomologs  Estimate kcats from measured homologs and keep them as a source file.
    +
    + For each reaction, enzyme and substrate (the substrates DLKcat would use,
    + see extractEnzymeSubstratePairs), the enzyme's sequence is searched with
    + DIAMOND against the sequences of the BRENDA measurements (at least 40%
    + identity, 80% coverage of both sequences). Each homolog measured on the
    + same substrate (same InChIKey, without the protonation flag) contributes
    + the median of its measurements; the estimate is the mean of the k most
    + identical such homologs, weighted by identity. Homologs at 95% identity or
    + more are measurements of (nearly) the same protein: when there are any,
    + the estimate is the median of those alone. For an enzyme complex the
    + estimate is the median over its subunits. Model metabolites are matched to
    + InChIKeys through substrates.tsv of the BRENDA files: their ChEBI
    + annotations, then MetaNetX annotations (model.metMiriams), then their
    + names. Reactions without a homolog measured on one of their substrates get
    + no value. The result is written to data/kcats/homologs.tsv (see
    + saveKcatSource). DIAMOND is RAVEN's (getDiamond; downloaded when
    + missing). geckopy has the same (kcats_from_homologs).
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure), with enzyme
    +     sequences (model.ec.sequence).
    +
    + Name-Value Arguments
    + --------------------
    + k : double
    +     the number of most identical homologs averaged (default 10).
    + minIdentity : double
    +     DIAMOND identity threshold, as a fraction (default 0.4).
    + coverage : double
    +     DIAMOND coverage threshold of both sequences, as a fraction (default 0.8).
    + threads : double
    +     DIAMOND threads (default: DIAMOND's).
    + save : logical
    +     write the source file (default true).
    + saveAs : char
    +     name of the source file, without .tsv (default 'homologs').
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + kcatList : struct
    +     the kcat values, with fields source, rxns, substrates, kcats and
    +     detail (the identity of the nearest homolog, identity, and the number
    +     of homologs used, n).
    +
    + Examples
    + --------
    +     kcatsFromHomologs(ecModel);
    +
    + See also
    + --------
    + kcatsFromECTree, extractEnzymeSubstratePairs, saveKcatSource, collectKcats
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: + +This function is called by: +
      +
    • updateKcatSources updateKcatSources Gather the kcat sources that the configuration needs.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function kcatList = kcatsFromHomologs(model, varargin)
    +0002 % kcatsFromHomologs  Estimate kcats from measured homologs and keep them as a source file.
    +0003 %
    +0004 % For each reaction, enzyme and substrate (the substrates DLKcat would use,
    +0005 % see extractEnzymeSubstratePairs), the enzyme's sequence is searched with
    +0006 % DIAMOND against the sequences of the BRENDA measurements (at least 40%
    +0007 % identity, 80% coverage of both sequences). Each homolog measured on the
    +0008 % same substrate (same InChIKey, without the protonation flag) contributes
    +0009 % the median of its measurements; the estimate is the mean of the k most
    +0010 % identical such homologs, weighted by identity. Homologs at 95% identity or
    +0011 % more are measurements of (nearly) the same protein: when there are any,
    +0012 % the estimate is the median of those alone. For an enzyme complex the
    +0013 % estimate is the median over its subunits. Model metabolites are matched to
    +0014 % InChIKeys through substrates.tsv of the BRENDA files: their ChEBI
    +0015 % annotations, then MetaNetX annotations (model.metMiriams), then their
    +0016 % names. Reactions without a homolog measured on one of their substrates get
    +0017 % no value. The result is written to data/kcats/homologs.tsv (see
    +0018 % saveKcatSource). DIAMOND is RAVEN's (getDiamond; downloaded when
    +0019 % missing). geckopy has the same (kcats_from_homologs).
    +0020 %
    +0021 % Parameters
    +0022 % ----------
    +0023 % model : struct
    +0024 %     an ecModel in GECKO 3 format (with ecModel.ec structure), with enzyme
    +0025 %     sequences (model.ec.sequence).
    +0026 %
    +0027 % Name-Value Arguments
    +0028 % --------------------
    +0029 % k : double
    +0030 %     the number of most identical homologs averaged (default 10).
    +0031 % minIdentity : double
    +0032 %     DIAMOND identity threshold, as a fraction (default 0.4).
    +0033 % coverage : double
    +0034 %     DIAMOND coverage threshold of both sequences, as a fraction (default 0.8).
    +0035 % threads : double
    +0036 %     DIAMOND threads (default: DIAMOND's).
    +0037 % save : logical
    +0038 %     write the source file (default true).
    +0039 % saveAs : char
    +0040 %     name of the source file, without .tsv (default 'homologs').
    +0041 % modelAdapter : ModelAdapter
    +0042 %     a loaded model adapter (default: the current default model adapter).
    +0043 %
    +0044 % Returns
    +0045 % -------
    +0046 % kcatList : struct
    +0047 %     the kcat values, with fields source, rxns, substrates, kcats and
    +0048 %     detail (the identity of the nearest homolog, identity, and the number
    +0049 %     of homologs used, n).
    +0050 %
    +0051 % Examples
    +0052 % --------
    +0053 %     kcatsFromHomologs(ecModel);
    +0054 %
    +0055 % See also
    +0056 % --------
    +0057 % kcatsFromECTree, extractEnzymeSubstratePairs, saveKcatSource, collectKcats
    +0058 
    +0059 checkOptions(varargin, {'k','minIdentity','coverage','threads','save','saveAs','modelAdapter'}, 'kcatsFromHomologs');
    +0060 p = parseGECKOargs(varargin, { ...
    +0061     'k',            10; ...
    +0062     'minIdentity',  0.4; ...
    +0063     'coverage',     0.8; ...
    +0064     'threads',      []; ...
    +0065     'save',         true; ...
    +0066     'saveAs',       'homologs'; ...
    +0067     'modelAdapter', []});
    +0068 modelAdapter = p.modelAdapter;
    +0069 if isempty(modelAdapter)
    +0070     modelAdapter = ModelAdapterManager.getDefault();
    +0071     if isempty(modelAdapter)
    +0072         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0073     end
    +0074 end
    +0075 
    +0076 measurements = loadBrendaMeasurements('folder', fileparts(brendaFile(modelAdapter, 'measurements.tsv')));
    +0077 substrates = readSubstrates(brendaFile(modelAdapter, 'substrates.tsv'));
    +0078 sequencesFile = brendaFile(modelAdapter, 'sequences.fasta');
    +0079 
    +0080 pairs = extractEnzymeSubstratePairs(model, 'modelAdapter', modelAdapter);
    +0081 iks = metaboliteInchikeys(model, substrates);
    +0082 pairIk = iks(pairs.met);
    +0083 seqs = model.ec.sequence(pairs.protein);
    +0084 keep = ~cellfun(@isempty, pairIk) & ~cellfun(@isempty, seqs);
    +0085 rxnIdx = pairs.ecRxn(keep); metIdx = pairs.met(keep); pairIk = pairIk(keep); seqs = seqs(keep);
    +0086 
    +0087 kcatList.source = 'homologs';
    +0088 kcatList.rxns = cell(0, 1);
    +0089 kcatList.substrates = cell(0, 1);
    +0090 kcatList.kcats = zeros(0, 1);
    +0091 kcatList.detail = cell(0, 1);
    +0092 if ~isempty(seqs)
    +0093     [useqs, ~, seqNo] = unique(seqs, 'stable');
    +0094     queryIds = cellstr(compose('q%d', (0:numel(useqs)-1)'));
    +0095     hits = diamondHits(queryIds, useqs, sequencesFile, p.minIdentity, p.coverage, p.threads);
    +0096     % Median log10 kcat per measured sequence and substrate.
    +0097     hasSeq = ~cellfun(@isempty, measurements.seq_id) & ~cellfun(@isempty, measurements.substrate_inchikey);
    +0098     key = strcat(measurements.seq_id(hasSeq), '|', cellfun(@(s) s(1:min(25, end)), ...
    +0099         measurements.substrate_inchikey(hasSeq), 'UniformOutput', false));
    +0100     [ukey, ~, g] = unique(key);
    +0101     med = containers.Map(ukey, num2cell(accumarray(g, measurements.log10kcat(hasSeq), [], @median)));
    +0102     % Estimate per enzyme sequence and substrate.
    +0103     [up, ~, pairNo] = unique(strcat(queryIds(seqNo), '|', pairIk), 'stable');
    +0104     est = nan(numel(up), 1); best = nan(numel(up), 1); nHom = zeros(numel(up), 1);
    +0105     for u = 1:numel(up)
    +0106         parts = strsplit(up{u}, '|');
    +0107         rows = find(strcmp(hits.query, parts{1}));
    +0108         found = zeros(0, 2);
    +0109         for r = rows(:)'
    +0110             mk = [hits.target{r} '|' parts{2}];
    +0111             if isKey(med, mk)
    +0112                 found(end+1, :) = [hits.identity(r), med(mk)]; %#ok<AGROW>
    +0113             end
    +0114         end
    +0115         if isempty(found)
    +0116             continue
    +0117         end
    +0118         exact = found(found(:, 1) >= 0.95, 2);
    +0119         best(u) = found(1, 1);
    +0120         if ~isempty(exact)
    +0121             est(u) = median(exact);
    +0122             nHom(u) = numel(exact);
    +0123         else
    +0124             found = found(1:min(p.k, end), :);
    +0125             est(u) = sum(found(:, 1) .* found(:, 2)) / sum(found(:, 1));
    +0126             nHom(u) = size(found, 1);
    +0127         end
    +0128     end
    +0129     % One row per reaction and substrate: the median over its enzymes.
    +0130     [ur, ~, rs] = unique(strcat(model.ec.rxns(rxnIdx), '|', model.metNames(metIdx)), 'stable');
    +0131     for r = 1:numel(ur)
    +0132         members = unique(pairNo(rs == r));
    +0133         members = members(~isnan(est(members)));
    +0134         if isempty(members)
    +0135             continue
    +0136         end
    +0137         [~, b] = max(best(members));
    +0138         first = find(rs == r, 1);
    +0139         kcatList.rxns{end+1, 1} = model.ec.rxns{rxnIdx(first)};
    +0140         kcatList.substrates{end+1, 1} = model.metNames{metIdx(first)};
    +0141         kcatList.kcats(end+1, 1) = 10 ^ median(est(members));
    +0142         kcatList.detail{end+1, 1} = sprintf('identity=%.3f; n=%d', best(members(b)), nHom(members(b)));
    +0143     end
    +0144 end
    +0145 
    +0146 if p.save
    +0147     parameters = struct('coverage', p.coverage, 'k', p.k, 'min_identity', p.minIdentity);
    +0148     file = saveKcatSource(model, kcatList, p.saveAs, 'modelAdapter', modelAdapter, ...
    +0149         'generator', 'kcatsFromHomologs', 'parameters', parameters, 'data', measurements.release);
    +0150     fprintf('Homolog kcats for %d reactions written to %s\n', numel(unique(kcatList.rxns)), file);
    +0151 end
    +0152 end
    +0153 
    +0154 function file = brendaFile(modelAdapter, name)
    +0155 % A file of the adapter's BRENDA folder, or of GECKO's BRENDA release.
    +0156 file = fullfile(modelAdapter.getBrendaDBFolder(), name);
    +0157 if ~isfile(file)
    +0158     file = fullfile(fetchBrendaAsset({name}), name);
    +0159 end
    +0160 end
    +0161 
    +0162 function s = readSubstrates(file)
    +0163 fid = fopen(file, 'r', 'n', 'UTF-8');
    +0164 c = textscan(fid, '%s %s %s', 'Delimiter', '\t', 'CommentStyle', '#', 'HeaderLines', 0);
    +0165 fclose(fid);
    +0166 header = strcmp(c{1}, 'inchikey');
    +0167 s.inchikey = c{1}(~header); s.kind = c{2}(~header); s.value = c{3}(~header);
    +0168 end
    +0169 
    +0170 function iks = metaboliteInchikeys(model, substrates)
    +0171 % InChIKey (first 25 characters) per model metabolite, '' when unknown:
    +0172 % from its ChEBI annotations, then its MetaNetX annotations, then its name.
    +0173 maps = struct();
    +0174 for kind = {'chebi', 'metanetx', 'name'}
    +0175     k = strcmp(substrates.kind, kind{1});
    +0176     [values, first] = unique(substrates.value(k), 'stable');
    +0177     ik = substrates.inchikey(k);
    +0178     maps.(kind{1}) = containers.Map('KeyType', 'char', 'ValueType', 'char');
    +0179     if ~isempty(values)
    +0180         maps.(kind{1}) = containers.Map(values, ik(first));
    +0181     end
    +0182 end
    +0183 iks = repmat({''}, numel(model.mets), 1);
    +0184 for i = 1:numel(model.mets)
    +0185     for pair = {{'chebi', 'chebi'}, {'metanetx', 'metanetx.chemical'}}
    +0186         kind = pair{1}{1};
    +0187         for v = annotations(model, i, pair{1}{2})
    +0188             if isKey(maps.(kind), v{1})
    +0189                 iks{i} = maps.(kind)(v{1});
    +0190                 break
    +0191             end
    +0192         end
    +0193         if ~isempty(iks{i})
    +0194             break
    +0195         end
    +0196     end
    +0197     if isempty(iks{i}) && isKey(maps.name, compactName(model.metNames{i}))
    +0198         iks{i} = maps.name(compactName(model.metNames{i}));
    +0199     end
    +0200 end
    +0201 end
    +0202 
    +0203 function values = annotations(model, i, key)
    +0204 % The identifiers of one annotation of a metabolite, without their prefix.
    +0205 values = {};
    +0206 if ~isfield(model, 'metMiriams') || numel(model.metMiriams) < i || ~isstruct(model.metMiriams{i})
    +0207     return
    +0208 end
    +0209 m = model.metMiriams{i};
    +0210 hit = strcmpi(m.name, key);
    +0211 values = regexprep(strtrim(m.value(hit)), '^.*:', '');
    +0212 values = values(:)';
    +0213 end
    +0214 
    +0215 function s = compactName(name)
    +0216 % A name as the compact keys of substrates.tsv: without markup, Greek letters
    +0217 % spelled out, accents dropped, lower case, only letters, digits and +.
    +0218 s = regexprep(char(name), '<[^>]+>', '');
    +0219 s = strrep(strrep(strrep(strrep(strrep(s, '&amp;', '&'), '&lt;', '<'), '&gt;', '>'), '&quot;', '"'), '&#39;', '''');
    +0220 greek = {char(945), 'alpha'; char(946), 'beta'; char(947), 'gamma'; char(948), 'delta'; char(949), 'epsilon'; ...
    +0221     char(969), 'omega'; char(954), 'kappa'; char(955), 'lambda'; char(956), 'mu'; char(968), 'psi'; ...
    +0222     char(958), 'xi'; char(950), 'zeta'};
    +0223 for g = 1:size(greek, 1)
    +0224     s = strrep(strrep(s, greek{g, 1}, greek{g, 2}), upper(greek{g, 1}), greek{g, 2});
    +0225 end
    +0226 s = char(javaMethod('normalize', 'java.text.Normalizer', java.lang.String(s), ...
    +0227     javaMethod('valueOf', 'java.text.Normalizer$Form', 'NFKD')));
    +0228 s = s(double(s) < 128);
    +0229 s = regexprep(lower(s), '[^a-z0-9+]', '');
    +0230 end
    +0231 
    +0232 function hits = diamondHits(ids, sequences, targetFasta, minIdentity, coverage, threads)
    +0233 % DIAMOND hits of the query sequences against a FASTA file: query, target,
    +0234 % identity (a fraction), best identity first per query, then by target.
    +0235 ravenPath = findRAVENroot();
    +0236 if ismac
    +0237     binEnd = '.mac';
    +0238 elseif ispc
    +0239     binEnd = '.exe';
    +0240 else
    +0241     binEnd = '';
    +0242 end
    +0243 exe = fullfile(ravenPath, 'src', 'external', 'diamond', ['diamond' binEnd]);
    +0244 if ~isfile(exe)
    +0245     downloadRavenBinaries({'diamond'});
    +0246 end
    +0247 tmp = tempname; mkdir(tmp);
    +0248 cleanup = onCleanup(@() rmdir(tmp, 's'));
    +0249 fid = fopen(fullfile(tmp, 'queries.fasta'), 'w');
    +0250 entries = [cellstr(ids(:))'; cellstr(sequences(:))'];
    +0251 fprintf(fid, '>%s\n%s\n', entries{:});
    +0252 fclose(fid);
    +0253 run = @(args) system(['"' exe '" ' args]);
    +0254 [status, out] = run(sprintf('makedb --in "%s" --db "%s" --quiet', targetFasta, fullfile(tmp, 'targets')));
    +0255 if status ~= 0
    +0256     error('kcatsFromHomologs:diamond', 'DIAMOND makedb failed: %s', out)
    +0257 end
    +0258 args = sprintf(['blastp --query "%s" --db "%s" --out "%s" --ultra-sensitive --id %g --query-cover %g ' ...
    +0259     '--subject-cover %g --evalue 0.001 --max-target-seqs 0 --outfmt 6 qseqid sseqid pident --quiet'], ...
    +0260     fullfile(tmp, 'queries.fasta'), fullfile(tmp, 'targets'), fullfile(tmp, 'hits.tsv'), ...
    +0261     100 * minIdentity, 100 * coverage, 100 * coverage);
    +0262 if ~isempty(threads)
    +0263     args = sprintf('%s --threads %d', args, threads);
    +0264 end
    +0265 [status, out] = run(args);
    +0266 if status ~= 0
    +0267     error('kcatsFromHomologs:diamond', 'DIAMOND blastp failed: %s', out)
    +0268 end
    +0269 fid = fopen(fullfile(tmp, 'hits.tsv'), 'r');
    +0270 c = textscan(fid, '%s %s %f', 'Delimiter', '\t');
    +0271 fclose(fid);
    +0272 q = c{1}; t = c{2}; ident = c{3} / 100;
    +0273 % Best identity per query and target.
    +0274 [pairKeys, ~, g] = unique(strcat(q, '|', t));
    +0275 ident = accumarray(g, ident, [], @max);
    +0276 parts = split(pairKeys, '|');
    +0277 if isempty(pairKeys)
    +0278     parts = cell(0, 2);
    +0279 end
    +0280 parts = reshape(parts, [], 2);
    +0281 T = table(parts(:, 1), parts(:, 2), ident, 'VariableNames', {'query', 'target', 'identity'});
    +0282 T = sortrows(T, {'query', 'identity', 'target'}, {'ascend', 'descend', 'ascend'});
    +0283 hits = struct('query', {T.query}, 'target', {T.target}, 'identity', T.identity);
    +0284 end
    +0285 
    +0286 function checkOptions(args, names, functionName)
    +0287 % Options are name-value pairs with known names, so a misspelled option is
    +0288 % an error instead of being taken as a positional argument.
    +0289 id = [functionName ':arguments'];
    +0290 given = args(1:2:end);
    +0291 if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given))
    +0292     error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', '))
    +0293 end
    +0294 unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names);
    +0295 if ~isempty(unknown)
    +0296     error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ...
    +0297         strjoin(names, ', '))
    +0298 end
    +0299 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/kcatsFromOKP.html b/doc/src/gather_kcats/kcatsFromOKP.html new file mode 100644 index 00000000..de090b9d --- /dev/null +++ b/doc/src/gather_kcats/kcatsFromOKP.html @@ -0,0 +1,369 @@ + + + + Description of kcatsFromOKP + + + + + + + + + +
    Home > src > gather_kcats > kcatsFromOKP.m
    + + + +

    kcatsFromOKP +

    + +

    PURPOSE ^

    +
    kcatsFromOKP Gather kcats from OpenKineticsPredictor and keep them as a source file.
    + +

    SYNOPSIS ^

    +
    function [kcatList, done] = kcatsFromOKP(model, varargin)
    + +

    DESCRIPTION ^

    +
     kcatsFromOKP  Gather kcats from OpenKineticsPredictor and keep them as a source file.
    +
    + Predicts kcats with one OpenKineticsPredictor (OKP) method and writes
    + them to data/kcats/okp_<method>.tsv in the project folder (see
    + saveKcatSource). OKP is a web service with a job queue, so this function
    + can be called repeatedly:
    +
    + - without a job for this method, it submits one
    +   (submitOpenKineticsPredictor);
    + - with a job, it fetches the result (fetchOpenKineticsPredictor). When
    +   the job is done the file is written; otherwise it reports the job's
    +   status and writes nothing.
    +
    + Each method keeps its own job in data/OKP_job_<method>.txt and its own
    + result in data/OKP_output_<method>.csv, so jobs of several methods can
    + run at the same time. The job file records which job the stored result
    + came from; useStored only uses a result of the current job. An API key
    + is needed (see resolveOkpApiKey).
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure), with
    +     metabolite SMILES (findMetSmiles) and protein sequences.
    +
    + Name-Value Arguments
    + --------------------
    + method : char
    +     OKP method, e.g. 'CataPro', 'CatPred', 'CatRange', 'DLKcat',
    +     'EITLEM', 'KinForm-H', 'KinForm-L', 'OmniESI', 'TurNup', 'UniKP'
    +     (default: params.okp.method of the model adapter, or 'CataPro').
    + wait : logical
    +     wait until the job is done (default false).
    + resubmit : logical
    +     submit a new job even if one exists for this method; its earlier
    +     result is removed (default false).
    + useStored : logical
    +     read the stored result of this method's job, without contacting OKP
    +     (default false).
    + ecRxns : logical
    +     for which model.ec.rxns kcats are predicted (default: all). Only
    +     used when a job is submitted.
    + save : logical
    +     write the source file (default true).
    + saveAs : char
    +     name of the source file, without .tsv (default 'okp_<method>', in
    +     lower case, with other characters than letters and digits as '_').
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + kcatList : struct
    +     the kcat values, as returned by readOpenKineticsPredictorOutput;
    +     empty while the job is not done.
    + done : logical
    +     whether the result was available.
    +
    + Examples
    + --------
    +     kcatsFromOKP(ecModel, 'method', 'CataPro');          % submits
    +     kcatsFromOKP(ecModel, 'method', 'CataPro');          % later: fetches and writes
    +     kcatsFromOKP(ecModel, 'method', 'UniKP', 'wait', true);
    +
    + See also
    + --------
    + submitOpenKineticsPredictor, fetchOpenKineticsPredictor, kcatsFromBrenda, saveKcatSource
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: + +This function is called by: +
      +
    • updateKcatSources updateKcatSources Gather the kcat sources that the configuration needs.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [kcatList, done] = kcatsFromOKP(model, varargin)
    +0002 % kcatsFromOKP  Gather kcats from OpenKineticsPredictor and keep them as a source file.
    +0003 %
    +0004 % Predicts kcats with one OpenKineticsPredictor (OKP) method and writes
    +0005 % them to data/kcats/okp_<method>.tsv in the project folder (see
    +0006 % saveKcatSource). OKP is a web service with a job queue, so this function
    +0007 % can be called repeatedly:
    +0008 %
    +0009 % - without a job for this method, it submits one
    +0010 %   (submitOpenKineticsPredictor);
    +0011 % - with a job, it fetches the result (fetchOpenKineticsPredictor). When
    +0012 %   the job is done the file is written; otherwise it reports the job's
    +0013 %   status and writes nothing.
    +0014 %
    +0015 % Each method keeps its own job in data/OKP_job_<method>.txt and its own
    +0016 % result in data/OKP_output_<method>.csv, so jobs of several methods can
    +0017 % run at the same time. The job file records which job the stored result
    +0018 % came from; useStored only uses a result of the current job. An API key
    +0019 % is needed (see resolveOkpApiKey).
    +0020 %
    +0021 % Parameters
    +0022 % ----------
    +0023 % model : struct
    +0024 %     an ecModel in GECKO 3 format (with ecModel.ec structure), with
    +0025 %     metabolite SMILES (findMetSmiles) and protein sequences.
    +0026 %
    +0027 % Name-Value Arguments
    +0028 % --------------------
    +0029 % method : char
    +0030 %     OKP method, e.g. 'CataPro', 'CatPred', 'CatRange', 'DLKcat',
    +0031 %     'EITLEM', 'KinForm-H', 'KinForm-L', 'OmniESI', 'TurNup', 'UniKP'
    +0032 %     (default: params.okp.method of the model adapter, or 'CataPro').
    +0033 % wait : logical
    +0034 %     wait until the job is done (default false).
    +0035 % resubmit : logical
    +0036 %     submit a new job even if one exists for this method; its earlier
    +0037 %     result is removed (default false).
    +0038 % useStored : logical
    +0039 %     read the stored result of this method's job, without contacting OKP
    +0040 %     (default false).
    +0041 % ecRxns : logical
    +0042 %     for which model.ec.rxns kcats are predicted (default: all). Only
    +0043 %     used when a job is submitted.
    +0044 % save : logical
    +0045 %     write the source file (default true).
    +0046 % saveAs : char
    +0047 %     name of the source file, without .tsv (default 'okp_<method>', in
    +0048 %     lower case, with other characters than letters and digits as '_').
    +0049 % modelAdapter : ModelAdapter
    +0050 %     a loaded model adapter (default: the current default model adapter).
    +0051 %
    +0052 % Returns
    +0053 % -------
    +0054 % kcatList : struct
    +0055 %     the kcat values, as returned by readOpenKineticsPredictorOutput;
    +0056 %     empty while the job is not done.
    +0057 % done : logical
    +0058 %     whether the result was available.
    +0059 %
    +0060 % Examples
    +0061 % --------
    +0062 %     kcatsFromOKP(ecModel, 'method', 'CataPro');          % submits
    +0063 %     kcatsFromOKP(ecModel, 'method', 'CataPro');          % later: fetches and writes
    +0064 %     kcatsFromOKP(ecModel, 'method', 'UniKP', 'wait', true);
    +0065 %
    +0066 % See also
    +0067 % --------
    +0068 % submitOpenKineticsPredictor, fetchOpenKineticsPredictor, kcatsFromBrenda, saveKcatSource
    +0069 
    +0070 checkOptions(varargin, {'method','wait','resubmit','useStored','ecRxns','save','saveAs','modelAdapter'}, 'kcatsFromOKP');
    +0071 p = parseGECKOargs(varargin, { ...
    +0072     'method',       []; ...
    +0073     'wait',         false; ...
    +0074     'resubmit',     false; ...
    +0075     'useStored',    false; ...
    +0076     'ecRxns',       []; ...
    +0077     'save',         true; ...
    +0078     'saveAs',       []; ...
    +0079     'modelAdapter', []});
    +0080 modelAdapter = p.modelAdapter;
    +0081 if isempty(modelAdapter)
    +0082     modelAdapter = ModelAdapterManager.getDefault();
    +0083     if isempty(modelAdapter)
    +0084         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0085     end
    +0086 end
    +0087 params = modelAdapter.params;
    +0088 method = char(p.method);
    +0089 if isempty(method)
    +0090     if isfield(params, 'okp') && isfield(params.okp, 'method') && ~isempty(params.okp.method)
    +0091         method = char(params.okp.method);
    +0092     else
    +0093         method = 'CataPro';
    +0094     end
    +0095 end
    +0096 if any(strcmp(method, {'CatPred', 'TurNup'}))
    +0097     error('kcatsFromOKP:method', ['%s reads whole reactions (its substrate set, and products ' ...
    +0098         'for TurNup); kcatsFromOKP submits enzyme-substrate pairs only.'], method)
    +0099 end
    +0100 tag = lower(regexprep(method, '[^A-Za-z0-9]+', '_'));
    +0101 dataDir = fullfile(params.path, 'data');
    +0102 jobFile = fullfile(dataDir, ['OKP_job_' tag '.txt']);
    +0103 outFile = fullfile(dataDir, ['OKP_output_' tag '.csv']);
    +0104 name = char(p.saveAs);
    +0105 if isempty(name)
    +0106     name = ['okp_' tag];
    +0107 end
    +0108 job = readJobFile(jobFile);
    +0109 submitting = ~p.useStored && (p.resubmit || ~isfield(job, 'jobId'));
    +0110 if ~isempty(p.ecRxns) && ~submitting
    +0111     error('kcatsFromOKP:ecRxns', ['ecRxns selects the reactions of a new job, but this call ' ...
    +0112         'submits none (a job for %s exists; use ''resubmit'', true for a new one).'], method)
    +0113 end
    +0114 if p.save
    +0115     file = fullfile(modelAdapter.params.path, 'data', 'kcats', [char(name) '.tsv']);
    +0116     if submitting
    +0117         warnSubset(p.ecRxns, numel(model.ec.rxns), file);
    +0118     end
    +0119 end
    +0120 
    +0121 if p.useStored
    +0122     if ~isfield(job, 'jobId')
    +0123         adoptSharedResult(model, modelAdapter, dataDir, method, jobFile, outFile);
    +0124         job = readJobFile(jobFile);
    +0125     end
    +0126     if ~isfile(outFile) || ~isfield(job, 'resultOf') || ~strcmp(job.resultOf, job.jobId)
    +0127         error('kcatsFromOKP:noStored', ['No stored result of the current %s job (%s). Call ' ...
    +0128             'kcatsFromOKP without ''useStored'' to fetch it.'], method, jobFile)
    +0129     end
    +0130     kcatList = readOpenKineticsPredictorOutput(model, 'outFile', outFile, 'modelAdapter', modelAdapter);
    +0131     done = true;
    +0132 else
    +0133     if submitting
    +0134         if isfile(outFile)
    +0135             delete(outFile);
    +0136         end
    +0137         jobId = submitOpenKineticsPredictor(model, 'method', method, 'ecRxns', p.ecRxns, ...
    +0138             'overwrite', true, 'modelAdapter', modelAdapter);
    +0139         job = struct('jobId', jobId, 'method', method, 'submittedAt', ...
    +0140             char(datetime('now', 'TimeZone', 'UTC', 'Format', 'yyyy-MM-dd''T''HH:mm:ss''Z''')));
    +0141         if ~isempty(p.ecRxns)
    +0142             job.ecRxns = sprintf('%d', countRxns(p.ecRxns));
    +0143         end
    +0144         writeJobFile(jobFile, job);
    +0145     end
    +0146     [done, kcatList] = fetchOpenKineticsPredictor(model, 'jobId', job.jobId, 'wait', p.wait, ...
    +0147         'outFile', outFile, 'modelAdapter', modelAdapter);
    +0148     if done
    +0149         job.resultOf = job.jobId;
    +0150         writeJobFile(jobFile, job);
    +0151     end
    +0152 end
    +0153 
    +0154 if ~done
    +0155     fprintf('Call kcatsFromOKP(model, ''method'', ''%s'') again later to collect the result.\n', method);
    +0156     return
    +0157 end
    +0158 if p.save
    +0159     parameters = struct('method', method);
    +0160     if isfield(job, 'ecRxns')
    +0161         parameters.ec_rxns = str2double(job.ecRxns);
    +0162     end
    +0163     if isfield(kcatList, 'similarity')
    +0164         kcatList.detail = repmat({''}, numel(kcatList.rxns), 1);
    +0165         has = ~isnan(kcatList.similarity);
    +0166         kcatList.detail(has) = cellstr("similarity=" + string(kcatList.similarity(has)));
    +0167     end
    +0168     saveKcatSource(model, kcatList, name, 'modelAdapter', modelAdapter, ...
    +0169         'generator', 'kcatsFromOKP', 'parameters', parameters, 'data', ['OKP job ' job.jobId]);
    +0170     fprintf('OKP (%s) kcats for %d reactions written to %s\n', method, ...
    +0171         numel(unique(kcatList.rxns(kcatList.kcats > 0))), file);
    +0172 end
    +0173 end
    +0174 
    +0175 function adoptSharedResult(model, modelAdapter, dataDir, method, jobFile, outFile)
    +0176 % A result that fetchOpenKineticsPredictor stored by itself, in
    +0177 % data/OKP_output.csv with data/OKP_job.txt, is taken over for this method
    +0178 % only when its job is for this method and its predictions are labelled
    +0179 % with this method.
    +0180 shared = fullfile(dataDir, 'OKP_output.csv');
    +0181 sharedJob = readJobFile(fullfile(dataDir, 'OKP_job.txt'));
    +0182 ok = isfile(shared) && isfield(sharedJob, 'jobId') && isfield(sharedJob, 'method') && ...
    +0183     strcmpi(sharedJob.method, method);
    +0184 if ok
    +0185     list = readOpenKineticsPredictorOutput(model, 'outFile', shared, 'modelAdapter', modelAdapter);
    +0186     predicted = list.kcatSource(startsWith(list.kcatSource, 'OKP-') & ...
    +0187         ~ismember(lower(list.kcatSource), {'okp-brenda','okp-sabio-rk','okp-uniprot'}));
    +0188     ok = ~isempty(predicted) && all(strcmpi(predicted, ['OKP-' method]));
    +0189 end
    +0190 if ~ok
    +0191     error('kcatsFromOKP:noStored', ['No stored OKP result for %s (%s). Call kcatsFromOKP ' ...
    +0192         'without ''useStored'' to submit or fetch a job.'], method, outFile)
    +0193 end
    +0194 copyfile(shared, outFile);
    +0195 sharedJob.method = method;
    +0196 sharedJob.resultOf = sharedJob.jobId;
    +0197 writeJobFile(jobFile, sharedJob);
    +0198 end
    +0199 
    +0200 function job = readJobFile(file)
    +0201 % Fields of an OKP job file ('key: value' per line), as a struct.
    +0202 job = struct();
    +0203 if ~isfile(file)
    +0204     return
    +0205 end
    +0206 lines = strsplit(fileread(file), newline);
    +0207 for i = 1:numel(lines)
    +0208     tok = regexp(lines{i}, '^([A-Za-z]\w*):\s*(.*?)\s*$', 'tokens', 'once');
    +0209     if ~isempty(tok)
    +0210         job.(tok{1}) = tok{2};
    +0211     end
    +0212 end
    +0213 end
    +0214 
    +0215 function writeJobFile(file, job)
    +0216 fid = fopen(file, 'w');
    +0217 for f = {'jobId','method','submittedAt','ecRxns','resultOf'}
    +0218     if isfield(job, f{1})
    +0219         fprintf(fid, '%s: %s\n', f{1}, job.(f{1}));
    +0220     end
    +0221 end
    +0222 fclose(fid);
    +0223 end
    +0224 
    +0225 function n = countRxns(ecRxns)
    +0226 if islogical(ecRxns)
    +0227     n = sum(ecRxns);
    +0228 else
    +0229     n = numel(unique(ecRxns));
    +0230 end
    +0231 end
    +0232 
    +0233 function warnSubset(ecRxns, nRxns, file)
    +0234 % A subset written under the default name replaces the full file.
    +0235 if ~isempty(ecRxns) && countRxns(ecRxns) < nRxns && isfile(file)
    +0236     printOrange(sprintf(['%s is replaced by kcats for %d reactions only. Give saveAs ' ...
    +0237         'to keep it.\n'], file, countRxns(ecRxns)));
    +0238 end
    +0239 end
    +0240 
    +0241 function checkOptions(args, names, functionName)
    +0242 % Options are name-value pairs with known names, so a misspelled option is
    +0243 % an error instead of being taken as a positional argument.
    +0244 id = [functionName ':arguments'];
    +0245 given = args(1:2:end);
    +0246 if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given))
    +0247     error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', '))
    +0248 end
    +0249 unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names);
    +0250 if ~isempty(unknown)
    +0251     error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ...
    +0252         strjoin(names, ', '))
    +0253 end
    +0254 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/loadBrendaMeasurements.html b/doc/src/gather_kcats/loadBrendaMeasurements.html new file mode 100644 index 00000000..d3b2f56f --- /dev/null +++ b/doc/src/gather_kcats/loadBrendaMeasurements.html @@ -0,0 +1,169 @@ + + + + Description of loadBrendaMeasurements + + + + + + + + + +
    Home > src > gather_kcats > loadBrendaMeasurements.m
    + + + +

    loadBrendaMeasurements +

    + +

    PURPOSE ^

    +
    loadBrendaMeasurements Load the BRENDA measurement table.
    + +

    SYNOPSIS ^

    +
    function measurements = loadBrendaMeasurements(varargin)
    + +

    DESCRIPTION ^

    +
     loadBrendaMeasurements  Load the BRENDA measurement table.
    +
    + Reads measurements.tsv from the BRENDA database folder of the model
    + adapter (next to kcat.tsv, sa.tsv and mw.tsv): one row per wild-type
    + BRENDA kcat with an EC number, after the outlier screen, with the
    + substrate, organism, UniProt accession and sequence id of each
    + measurement. geckopy reads the same file (load_brenda_measurements).
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + folder : char
    +     folder with measurements.tsv, instead of the adapter's BRENDA folder.
    +
    + Returns
    + -------
    + measurements : struct
    +     one field per column of the file (ec, substrate, substrate_inchikey,
    +     organism, taxid, uniprot, seq_id, temperature, ph and pmid as cell
    +     arrays of char; kcat as double), plus log10kcat and release (the
    +     release line of the file, e.g. 'BRENDA release 2026.1').
    +
    + Examples
    + --------
    +     measurements = loadBrendaMeasurements();
    +
    + See also
    + --------
    + kcatsFromECTree, ecTreeEstimate, loadBRENDAdata
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • kcatsFromECTree kcatsFromECTree Estimate kcats from the EC tree and keep them as a source file.
    • kcatsFromHomologs kcatsFromHomologs Estimate kcats from measured homologs and keep them as a source file.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function measurements = loadBrendaMeasurements(varargin)
    +0002 % loadBrendaMeasurements  Load the BRENDA measurement table.
    +0003 %
    +0004 % Reads measurements.tsv from the BRENDA database folder of the model
    +0005 % adapter (next to kcat.tsv, sa.tsv and mw.tsv): one row per wild-type
    +0006 % BRENDA kcat with an EC number, after the outlier screen, with the
    +0007 % substrate, organism, UniProt accession and sequence id of each
    +0008 % measurement. geckopy reads the same file (load_brenda_measurements).
    +0009 %
    +0010 % Name-Value Arguments
    +0011 % --------------------
    +0012 % modelAdapter : ModelAdapter
    +0013 %     a loaded model adapter (default: the current default model adapter).
    +0014 % folder : char
    +0015 %     folder with measurements.tsv, instead of the adapter's BRENDA folder.
    +0016 %
    +0017 % Returns
    +0018 % -------
    +0019 % measurements : struct
    +0020 %     one field per column of the file (ec, substrate, substrate_inchikey,
    +0021 %     organism, taxid, uniprot, seq_id, temperature, ph and pmid as cell
    +0022 %     arrays of char; kcat as double), plus log10kcat and release (the
    +0023 %     release line of the file, e.g. 'BRENDA release 2026.1').
    +0024 %
    +0025 % Examples
    +0026 % --------
    +0027 %     measurements = loadBrendaMeasurements();
    +0028 %
    +0029 % See also
    +0030 % --------
    +0031 % kcatsFromECTree, ecTreeEstimate, loadBRENDAdata
    +0032 
    +0033 checkOptions(varargin, {'modelAdapter','folder'}, 'loadBrendaMeasurements');
    +0034 p = parseGECKOargs(varargin, {'modelAdapter', []; 'folder', []});
    +0035 folder = p.folder;
    +0036 if isempty(folder)
    +0037     modelAdapter = p.modelAdapter;
    +0038     if isempty(modelAdapter)
    +0039         modelAdapter = ModelAdapterManager.getDefault();
    +0040         if isempty(modelAdapter)
    +0041             error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0042         end
    +0043     end
    +0044     folder = modelAdapter.getBrendaDBFolder();
    +0045 end
    +0046 file = fullfile(folder, 'measurements.tsv');
    +0047 if ~isfile(file)
    +0048     error('loadBrendaMeasurements:missing', ['No BRENDA measurement table (measurements.tsv) in %s. ' ...
    +0049         'It comes with the BRENDA files of GECKO (databases folder).'], folder)
    +0050 end
    +0051 fid = fopen(file, 'r', 'n', 'UTF-8');
    +0052 first = fgetl(fid);
    +0053 header = strsplit(fgetl(fid), '\t');
    +0054 data = textscan(fid, repmat('%s', 1, numel(header)), 'Delimiter', '\t', 'Whitespace', '', ...
    +0055     'ReturnOnError', false);
    +0056 fclose(fid);
    +0057 if ~all(ismember({'ec', 'kcat'}, header))
    +0058     error('loadBrendaMeasurements:columns', '%s lacks the columns ec and kcat.', file)
    +0059 end
    +0060 measurements = struct();
    +0061 for c = 1:numel(header)
    +0062     measurements.(matlab.lang.makeValidName(header{c})) = data{c};
    +0063 end
    +0064 measurements.kcat = str2double(measurements.kcat);
    +0065 keep = measurements.kcat > 0 & ~cellfun(@isempty, measurements.ec);
    +0066 for f = fieldnames(measurements)'
    +0067     measurements.(f{1}) = measurements.(f{1})(keep);
    +0068 end
    +0069 measurements.ec = strtrim(measurements.ec);
    +0070 measurements.log10kcat = log10(measurements.kcat);
    +0071 tok = regexp(first, '^#\s*(BRENDA release [^ ]+)', 'tokens', 'once');
    +0072 measurements.release = '';
    +0073 if ~isempty(tok)
    +0074     measurements.release = tok{1};
    +0075 end
    +0076 end
    +0077 
    +0078 function checkOptions(args, names, functionName)
    +0079 % Options are name-value pairs with known names, so a misspelled option is
    +0080 % an error instead of being taken as a positional argument.
    +0081 id = [functionName ':arguments'];
    +0082 given = args(1:2:end);
    +0083 if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given))
    +0084     error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', '))
    +0085 end
    +0086 unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names);
    +0087 if ~isempty(unknown)
    +0088     error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ...
    +0089         strjoin(names, ', '))
    +0090 end
    +0091 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/loadKcatSource.html b/doc/src/gather_kcats/loadKcatSource.html new file mode 100644 index 00000000..a0812da3 --- /dev/null +++ b/doc/src/gather_kcats/loadKcatSource.html @@ -0,0 +1,489 @@ + + + + Description of loadKcatSource + + + + + + + + + +
    Home > src > gather_kcats > loadKcatSource.m
    + + + +

    loadKcatSource +

    + +

    PURPOSE ^

    +
    loadKcatSource Read a kcat source file and map its rows to an ecModel.
    + +

    SYNOPSIS ^

    +
    function [kcatList, report] = loadKcatSource(model, name, varargin)
    + +

    DESCRIPTION ^

    +
     loadKcatSource  Read a kcat source file and map its rows to an ecModel.
    +
    + Reads data/kcats/<name>.tsv (see saveKcatSource) and maps every row to
    + the model.ec reactions it applies to, by conventional reaction and
    + enzyme set (see getEcRxnKeys):
    +
    + 1. A row with rxn and enzymes applies to the model.ec rows with that
    +    conventional reaction and that enzyme set.
    + 2. A row with only enzymes applies to every model.ec row with that
    +    enzyme set; a row with only rxn to every model.ec row of that
    +    conventional reaction (curated rows; saveKcatSource always writes
    +    both).
    + 3. A row whose kcat is missing, not a number, infinite, or not above 0
    +    is reported as invalid and not applied.
    + 4. A row that matches nothing is reported, never dropped silently. If a
    +    model.ec row has at least half of the row's enzymes, that partial
    +    match is reported as well, but not applied.
    +
    + The enzymes of a row may be listed in any order.
    +
    + The file is read as UTF-8 (a leading byte-order mark is ignored). The
    + '#' lines before the column header are the header; '#' lines and blank
    + lines further down are skipped. Fields wrapped in double quotes, as a
    + spreadsheet may save them, are unwrapped. kcat and log10_sd must be plain
    + numbers (12, 0.5, 1e-05); other text, such as '5,5' with a decimal comma,
    + is reported as invalid. A row with more filled fields than there are
    + columns is an error.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    + name : char
    +     name of the source (data/kcats/<name>.tsv in the project folder), or
    +     the path to a kcat source file.
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + kcatList : struct
    +     kcat values per model.ec reaction, as used by mergeKcats and
    +     assignKcatValues: source (the source name), rxns, kcats,
    +     substrates, eccodes, wildcardLvl and origin (from the detail
    +     column), kcatSource (the per-row source), log10sd, detail (the detail
    +     column), and line (the line of the file each entry comes from).
    + report : struct
    +     - invalid: table of the file rows with a missing or invalid kcat;
    +     - unmatched: table of the file rows that apply to no model.ec row;
    +     - partial: table of rows that only partly match an enzyme set, with
    +       the model.ec reaction and its enzymes;
    +     - header: the '#' header lines of the file, as field: value (for
    +       instance header.source, header.parameters);
    +     - records: the rows of the file as read, one field per column (kcat
    +       and log10_sd as double, other columns as cell of char) and line,
    +       the line number of each row.
    +
    + Examples
    + --------
    +     kcatList = loadKcatSource(ecModel, 'brenda');
    +     [kcatList, report] = loadKcatSource(ecModel, 'custom');
    +
    + See also
    + --------
    + saveKcatSource, kcatsFromBrenda, getEcRxnKeys
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • getEcRxnKeys getEcRxnKeys Build-independent keys of the model.ec reactions.
    +This function is called by: +
      +
    • collectKcats collectKcats Decide one kcat per reaction from the kcat source files.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [kcatList, report] = loadKcatSource(model, name, varargin)
    +0002 % loadKcatSource  Read a kcat source file and map its rows to an ecModel.
    +0003 %
    +0004 % Reads data/kcats/<name>.tsv (see saveKcatSource) and maps every row to
    +0005 % the model.ec reactions it applies to, by conventional reaction and
    +0006 % enzyme set (see getEcRxnKeys):
    +0007 %
    +0008 % 1. A row with rxn and enzymes applies to the model.ec rows with that
    +0009 %    conventional reaction and that enzyme set.
    +0010 % 2. A row with only enzymes applies to every model.ec row with that
    +0011 %    enzyme set; a row with only rxn to every model.ec row of that
    +0012 %    conventional reaction (curated rows; saveKcatSource always writes
    +0013 %    both).
    +0014 % 3. A row whose kcat is missing, not a number, infinite, or not above 0
    +0015 %    is reported as invalid and not applied.
    +0016 % 4. A row that matches nothing is reported, never dropped silently. If a
    +0017 %    model.ec row has at least half of the row's enzymes, that partial
    +0018 %    match is reported as well, but not applied.
    +0019 %
    +0020 % The enzymes of a row may be listed in any order.
    +0021 %
    +0022 % The file is read as UTF-8 (a leading byte-order mark is ignored). The
    +0023 % '#' lines before the column header are the header; '#' lines and blank
    +0024 % lines further down are skipped. Fields wrapped in double quotes, as a
    +0025 % spreadsheet may save them, are unwrapped. kcat and log10_sd must be plain
    +0026 % numbers (12, 0.5, 1e-05); other text, such as '5,5' with a decimal comma,
    +0027 % is reported as invalid. A row with more filled fields than there are
    +0028 % columns is an error.
    +0029 %
    +0030 % Parameters
    +0031 % ----------
    +0032 % model : struct
    +0033 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0034 % name : char
    +0035 %     name of the source (data/kcats/<name>.tsv in the project folder), or
    +0036 %     the path to a kcat source file.
    +0037 %
    +0038 % Name-Value Arguments
    +0039 % --------------------
    +0040 % modelAdapter : ModelAdapter
    +0041 %     a loaded model adapter (default: the current default model adapter).
    +0042 %
    +0043 % Returns
    +0044 % -------
    +0045 % kcatList : struct
    +0046 %     kcat values per model.ec reaction, as used by mergeKcats and
    +0047 %     assignKcatValues: source (the source name), rxns, kcats,
    +0048 %     substrates, eccodes, wildcardLvl and origin (from the detail
    +0049 %     column), kcatSource (the per-row source), log10sd, detail (the detail
    +0050 %     column), and line (the line of the file each entry comes from).
    +0051 % report : struct
    +0052 %     - invalid: table of the file rows with a missing or invalid kcat;
    +0053 %     - unmatched: table of the file rows that apply to no model.ec row;
    +0054 %     - partial: table of rows that only partly match an enzyme set, with
    +0055 %       the model.ec reaction and its enzymes;
    +0056 %     - header: the '#' header lines of the file, as field: value (for
    +0057 %       instance header.source, header.parameters);
    +0058 %     - records: the rows of the file as read, one field per column (kcat
    +0059 %       and log10_sd as double, other columns as cell of char) and line,
    +0060 %       the line number of each row.
    +0061 %
    +0062 % Examples
    +0063 % --------
    +0064 %     kcatList = loadKcatSource(ecModel, 'brenda');
    +0065 %     [kcatList, report] = loadKcatSource(ecModel, 'custom');
    +0066 %
    +0067 % See also
    +0068 % --------
    +0069 % saveKcatSource, kcatsFromBrenda, getEcRxnKeys
    +0070 
    +0071 checkOptions(varargin, {'modelAdapter'}, 'loadKcatSource');
    +0072 p = parseGECKOargs(varargin, {'modelAdapter', []});
    +0073 
    +0074 if isfile(name)
    +0075     filename = name;
    +0076 else
    +0077     modelAdapter = p.modelAdapter;
    +0078     if isempty(modelAdapter)
    +0079         modelAdapter = ModelAdapterManager.getDefault();
    +0080         if isempty(modelAdapter)
    +0081             error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0082         end
    +0083     end
    +0084     filename = fullfile(modelAdapter.params.path, 'data', 'kcats', [name '.tsv']);
    +0085     if ~isfile(filename)
    +0086         error('loadKcatSource:missing', ['No kcat source file %s. Make it with the ' ...
    +0087             'kcatsFrom<Source> function of this source (kcatsFromBrenda, kcatsFromDLKcat, ' ...
    +0088             'kcatsFromOKP), or with saveKcatSource.'], filename)
    +0089     end
    +0090 end
    +0091 [records, meta] = readSourceFile(filename);
    +0092 sourceName = '';
    +0093 if isfield(meta, 'source')
    +0094     sourceName = meta.source;
    +0095 end
    +0096 
    +0097 [baseRxns, enzymeSets] = getEcRxnKeys(model);
    +0098 nEc = numel(baseRxns);
    +0099 nRec = numel(records.kcat);
    +0100 
    +0101 % Lookup tables: key -> model.ec rows.
    +0102 byPair = groupIndex(strcat(baseRxns, '|', enzymeSets));
    +0103 byBase = groupIndex(baseRxns);
    +0104 byEnz  = groupIndex(enzymeSets);
    +0105 % accession -> model.ec rows containing it, for partial matches.
    +0106 accRows = cell(nEc, 1);
    +0107 for i = 1:nEc
    +0108     if ~isempty(enzymeSets{i})
    +0109         accRows{i} = strsplit(enzymeSets{i}, ' + ');
    +0110     end
    +0111 end
    +0112 accIdx = repelem((1:nEc)', cellfun(@numel, accRows));
    +0113 byAcc = groupIndex([accRows{:}]', accIdx);
    +0114 
    +0115 invalid = ~(records.kcat > 0) | ~isfinite(records.kcat);
    +0116 matchRec = cell(nRec, 1);
    +0117 matchEc  = cell(nRec, 1);
    +0118 unmatched = false(nRec, 1);
    +0119 partialRec = zeros(0, 1); partialEc = zeros(0, 1);
    +0120 for r = find(~invalid)'
    +0121     rxn = records.rxn{r};
    +0122     enz = normalizeEnzymes(records.enzymes{r});
    +0123     if ~isempty(rxn) && ~isempty(enz)
    +0124         hit = lookup(byPair, [rxn '|' enz]);
    +0125     elseif ~isempty(enz)
    +0126         hit = lookup(byEnz, enz);
    +0127     elseif ~isempty(rxn)
    +0128         hit = lookup(byBase, rxn);
    +0129     else
    +0130         hit = [];
    +0131     end
    +0132     if isempty(hit)
    +0133         unmatched(r) = true;
    +0134         if ~isempty(enz)
    +0135             wanted = strsplit(enz, ' + ');
    +0136             candidates = unique(cell2mat(cellfun(@(a) lookup(byAcc, a), wanted(:), 'UniformOutput', false)));
    +0137             if ~isempty(rxn)
    +0138                 candidates = intersect(candidates, lookup(byBase, rxn));
    +0139             end
    +0140             for c = candidates(:)'
    +0141                 if mean(ismember(wanted, accRows{c})) >= 0.5
    +0142                     partialRec(end+1, 1) = r; %#ok<AGROW>
    +0143                     partialEc(end+1, 1) = c; %#ok<AGROW>
    +0144                 end
    +0145             end
    +0146         end
    +0147     else
    +0148         matchRec{r} = repmat(r, numel(hit), 1);
    +0149         matchEc{r} = hit(:);
    +0150     end
    +0151 end
    +0152 rec = vertcat(matchRec{:}, zeros(0, 1));
    +0153 ec  = vertcat(matchEc{:}, zeros(0, 1));
    +0154 
    +0155 kcatList.source      = sourceName;
    +0156 kcatList.rxns        = reshape(model.ec.rxns(ec), [], 1);
    +0157 kcatList.kcats       = records.kcat(rec);
    +0158 kcatList.substrates  = records.substrate(rec);
    +0159 kcatList.eccodes     = records.ec_code(rec);
    +0160 kcatList.kcatSource  = records.source(rec);
    +0161 kcatList.log10sd     = records.log10_sd(rec);
    +0162 kcatList.detail      = records.detail(rec);
    +0163 [kcatList.wildcardLvl, kcatList.origin] = parseDetail(records.detail(rec));
    +0164 kcatList.line        = records.line(rec);
    +0165 
    +0166 report.invalid = table(records.line(invalid), records.rxn(invalid), records.enzymes(invalid), ...
    +0167     records.kcat(invalid), 'VariableNames', {'line','rxn','enzymes','kcat'});
    +0168 report.unmatched = table(records.line(unmatched), records.rxn(unmatched), records.enzymes(unmatched), ...
    +0169     records.kcat(unmatched), 'VariableNames', {'line','rxn','enzymes','kcat'});
    +0170 report.partial = table(records.line(partialRec), records.rxn(partialRec), records.enzymes(partialRec), ...
    +0171     reshape(model.ec.rxns(partialEc), [], 1), enzymeSets(partialEc), ...
    +0172     'VariableNames', {'line','rxn','enzymes','ecRxn','ecEnzymes'});
    +0173 if any(invalid)
    +0174     printOrange(sprintf('%d of %d rows of %s have no valid kcat; see report.invalid.\n', ...
    +0175         sum(invalid), nRec, filename));
    +0176 end
    +0177 if any(unmatched)
    +0178     printOrange(sprintf('%d of %d rows of %s apply to no reaction of this model; see report.unmatched.\n', ...
    +0179         sum(unmatched), nRec, filename));
    +0180 end
    +0181 report.header = meta;
    +0182 report.records = records;
    +0183 end
    +0184 
    +0185 function map = groupIndex(keys, rows)
    +0186 % containers.Map from each key to the rows (default 1:n) that have it.
    +0187 if nargin < 2
    +0188     rows = (1:numel(keys))';
    +0189 end
    +0190 map = containers.Map('KeyType', 'char', 'ValueType', 'any');
    +0191 if isempty(keys)
    +0192     return
    +0193 end
    +0194 [u, ~, g] = unique(keys(:));
    +0195 groups = accumarray(g, rows(:), [], @(x) {sort(x)});
    +0196 for i = 1:numel(u)
    +0197     if ~isempty(u{i})
    +0198         map(u{i}) = groups{i};
    +0199     end
    +0200 end
    +0201 end
    +0202 
    +0203 function rows = lookup(map, key)
    +0204 if isKey(map, key)
    +0205     rows = map(key);
    +0206 else
    +0207     rows = zeros(0, 1);
    +0208 end
    +0209 end
    +0210 
    +0211 function enz = normalizeEnzymes(enz)
    +0212 % Sorted and joined as getEcRxnKeys does, so hand-written rows match too.
    +0213 if isempty(enz)
    +0214     return
    +0215 end
    +0216 parts = strtrim(strsplit(enz, '+'));
    +0217 parts = unique(parts(~cellfun(@isempty, parts)));
    +0218 enz = strjoin(sort(parts(:)'), ' + ');
    +0219 end
    +0220 
    +0221 function [wc, origin] = parseDetail(detail)
    +0222 wc = nan(numel(detail), 1);
    +0223 origin = nan(numel(detail), 1);
    +0224 for i = 1:numel(detail)
    +0225     t = regexp(detail{i}, 'wc=(\d+)', 'tokens', 'once');
    +0226     if ~isempty(t)
    +0227         wc(i) = str2double(t{1});
    +0228     end
    +0229     t = regexp(detail{i}, 'origin=(\d+)', 'tokens', 'once');
    +0230     if ~isempty(t)
    +0231         origin(i) = str2double(t{1});
    +0232     end
    +0233 end
    +0234 end
    +0235 
    +0236 function [records, meta] = readSourceFile(filename)
    +0237 % The rows and '#' header lines of a kcat source file, as they are.
    +0238 text = readUtf8(filename);
    +0239 lines = regexp(text, '\r?\n', 'split');
    +0240 
    +0241 meta = struct();
    +0242 k = 1;
    +0243 while k <= numel(lines) && (isempty(strtrim(lines{k})) || startsWith(unquoteField(lines{k}), '#'))
    +0244     [key, value] = parseHeaderLine(lines{k});
    +0245     if ~isempty(key)
    +0246         meta.(key) = value;
    +0247     end
    +0248     k = k + 1;
    +0249 end
    +0250 if k > numel(lines)
    +0251     error('loadKcatSource:noHeader', '%s has no column header.', filename)
    +0252 end
    +0253 columns = cellfun(@unquoteField, strsplit(lines{k}, sprintf('\t'), ...
    +0254     'CollapseDelimiters', false), 'UniformOutput', false);
    +0255 if ~all(ismember({'kcat','source'}, columns)) || ~any(ismember({'rxn','enzymes'}, columns))
    +0256     error('loadKcatSource:columns', ['%s needs the columns kcat and source, and rxn ' ...
    +0257         'and/or enzymes.'], filename)
    +0258 end
    +0259 named = columns(~cellfun(@isempty, columns));
    +0260 if numel(unique(named)) < numel(named) || any(strcmp(columns, 'line'))
    +0261     error('loadKcatSource:columns', '%s has a column name twice, or a column named line.', filename)
    +0262 end
    +0263 nCol = numel(columns);
    +0264 
    +0265 trimmed = strtrim(lines);
    +0266 skip = cellfun(@isempty, trimmed) | startsWith(trimmed, '#') | startsWith(trimmed, '"#');
    +0267 skip(1:k) = true;
    +0268 kept = find(~skip);
    +0269 L = string(lines(kept));
    +0270 L = L(:);
    +0271 F = strings(numel(kept), nCol);
    +0272 nTabs = count(L, sprintf('\t'));
    +0273 regular = nTabs == nCol - 1;
    +0274 if any(regular)
    +0275     % Rows with exactly one field per column, split in one go.
    +0276     F(regular, :) = reshape(split(L(regular), sprintf('\t'), 2), [], nCol);
    +0277 end
    +0278 for r = find(~regular)'
    +0279     fields = strsplit(char(L(r)), sprintf('\t'), 'CollapseDelimiters', false);
    +0280     if numel(fields) > nCol
    +0281         if any(~cellfun(@isempty, strtrim(fields(nCol+1:end))))
    +0282             error('loadKcatSource:fields', '%s, line %d has more fields than the %d columns.', ...
    +0283                 filename, kept(r), nCol)
    +0284         end
    +0285         fields = fields(1:nCol);
    +0286     end
    +0287     fields(end+1:nCol) = {''};
    +0288     F(r, :) = string(fields);
    +0289 end
    +0290 F = strtrim(F);
    +0291 quoted = find(startsWith(F, '"'));
    +0292 for q = quoted(:)'
    +0293     F(q) = unquoteField(char(F(q)));
    +0294 end
    +0295 filled = any(F ~= "", 2); % a row of tabs only is skipped
    +0296 values = cellstr(F(filled, :));
    +0297 if isempty(values)
    +0298     values = cell(0, nCol);
    +0299 end
    +0300 lineNo = kept(filled);
    +0301 lineNo = lineNo(:);
    +0302 n = numel(lineNo);
    +0303 
    +0304 records = struct();
    +0305 for c = 1:nCol
    +0306     if isempty(columns{c})
    +0307         continue
    +0308     end
    +0309     name = matlab.lang.makeValidName(columns{c});
    +0310     v = values(:, c);
    +0311     if any(strcmp(columns{c}, {'kcat','log10_sd'}))
    +0312         v = parseKcatNumber(v);
    +0313     end
    +0314     records.(name) = v;
    +0315 end
    +0316 for c = {'rxn','enzymes','substrate','source','detail','ec_code','note'}
    +0317     if ~isfield(records, c{1})
    +0318         records.(c{1}) = repmat({''}, n, 1);
    +0319     end
    +0320 end
    +0321 if ~isfield(records, 'log10_sd')
    +0322     records.log10_sd = nan(n, 1);
    +0323 end
    +0324 records.line = lineNo;
    +0325 end
    +0326 
    +0327 function text = readUtf8(filename)
    +0328 fid = fopen(filename, 'r', 'n', 'UTF-8');
    +0329 if fid < 0
    +0330     error('loadKcatSource:read', 'Cannot read %s', filename)
    +0331 end
    +0332 cleanup = onCleanup(@() fclose(fid));
    +0333 text = fread(fid, [1 Inf], '*char');
    +0334 text = regexprep(text, ['^' char(65279)], '');
    +0335 end
    +0336 
    +0337 function x = parseKcatNumber(texts)
    +0338 % Plain numbers only: '5,5' or '12 /s' read as NaN.
    +0339 x = nan(numel(texts), 1);
    +0340 ok = ~cellfun(@isempty, regexp(texts(:), '^[-+]?(\d+\.?\d*|\.\d+)([eE][-+]?\d+)?$|^[-+]?Inf$', 'once'));
    +0341 x(ok) = str2double(texts(ok));
    +0342 end
    +0343 
    +0344 function [key, value] = parseHeaderLine(line)
    +0345 key = ''; value = '';
    +0346 tok = regexp(unquoteField(line), '^\s*#\s*([A-Za-z][A-Za-z0-9_]{0,62})\s*:\s?(.*)$', 'tokens', 'once');
    +0347 if ~isempty(tok)
    +0348     key = lower(tok{1});
    +0349     value = strtrim(tok{2});
    +0350 end
    +0351 end
    +0352 
    +0353 function t = unquoteField(t)
    +0354 t = strtrim(t);
    +0355 if numel(t) >= 2 && t(1) == '"' && t(end) == '"'
    +0356     t = strtrim(strrep(t(2:end-1), '""', '"'));
    +0357 end
    +0358 end
    +0359 
    +0360 function checkOptions(args, names, functionName)
    +0361 % Options are name-value pairs with known names, so a misspelled option is
    +0362 % an error instead of being taken as a positional argument.
    +0363 id = [functionName ':arguments'];
    +0364 given = args(1:2:end);
    +0365 if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given))
    +0366     error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', '))
    +0367 end
    +0368 unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names);
    +0369 if ~isempty(unknown)
    +0370     error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ...
    +0371         strjoin(names, ', '))
    +0372 end
    +0373 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/mergeDLKcatAndFuzzyKcats.html b/doc/src/gather_kcats/mergeDLKcatAndFuzzyKcats.html new file mode 100644 index 00000000..a284969c --- /dev/null +++ b/doc/src/gather_kcats/mergeDLKcatAndFuzzyKcats.html @@ -0,0 +1,215 @@ + + + + Description of mergeDLKcatAndFuzzyKcats + + + + + + + + + +
    Home > src > gather_kcats > mergeDLKcatAndFuzzyKcats.m
    + + + +

    mergeDLKcatAndFuzzyKcats +

    + +

    PURPOSE ^

    +
    mergeDLKcatAndFuzzyKcats Merge DLKcat and BRENDA fuzzy matching results.
    + +

    SYNOPSIS ^

    +
    function mergedKcatList = mergeDLKcatAndFuzzyKcats(kcatListDLKcat, kcatListFuzzy, varargin)
    + +

    DESCRIPTION ^

    +
     mergeDLKcatAndFuzzyKcats  Merge DLKcat and BRENDA fuzzy matching results.
    +
    + Deprecated thin wrapper around mergeKcats, kept for the common DLKcat +
    + fuzzy-BRENDA case. New code should call mergeKcats directly, which also
    + handles a single list that mixes several sources (e.g. an
    + OpenKineticsPredictor result with BRENDA/Sabio-RK/CataPro rows).
    +
    + Merges the results from DLKcat and fuzzy matching to the BRENDA database.
    + Order of preference:
    +
    + 1. BRENDA match with correct E.C. number, with origin (see below) not
    +    lower than the specified topOriginLimit.
    + 2. DLKcat match.
    + 3. BRENDA match with correct E.C. number, with origin below topOriginLimit
    +    but not lower than the bottomOriginLimit.
    + 4. BRENDA match with wildcards in the E.C. number, with not more wildcards
    +    than wildcardLimit, and origin not lower than the bottomOriginLimit.
    +
    + Parameters
    + ----------
    + kcatListDLKcat : struct
    +     kcatList derived from readDLKcatOutput.
    + kcatListFuzzy : struct
    +     kcatList derived from fuzzyKcatMatching.
    +
    + Name-Value Arguments
    + --------------------
    + topOriginLimit : double
    +     origin limit for prioritized BRENDA matches. Origin is explained in
    +     more detail below (default 4: BRENDA matches of origin 5 and 6, from
    +     specific activities, rank after DLKcat; use 6 to rank them above).
    + bottomOriginLimit : double
    +     origin limit for low priority BRENDA matches. Origin is explained in
    +     more detail below (default 6).
    + wildcardLimit : double
    +     maximum number of wildcards in E.C. number of BRENDA matches
    +     (default 3).
    +
    + Returns
    + -------
    + mergedKcatList : struct
    +     merged kcatList with the same field layout produced by mergeKcats
    +     (source, kcatSource, rxns, genes, substrates, kcats, eccodes,
    +     wildcardLvl, origin), keeping only the rows selected by the order of
    +     preference above.
    +
    + Notes
    + -----
    + The origin parameter:
    +
    + - 1 : correct organism, correct substrate, kcat.
    + - 2 : any organism, correct substrate, kcat.
    + - 3 : correct organism, any substrate, kcat.
    + - 4 : any organism, any substrate, kcat.
    + - 5 : correct organism, specific activity.
    + - 6 : any organism, specific activity.
    +
    + Example of wildcards in E.C. number:
    +
    + - 0 : 1.1.1.3   glycerol-3-phosphate dehydrogenase (NAD+).
    + - 1 : 1.1.1.-   oxidoreductase, acting on the CH-OH group of donors, with
    +   NAD+ or NADP+ as acceptor.
    + - 2 : 1.1.-.-   oxidoreductase, acting on the CH-OH group of donors.
    + - 3 : 1.-.-.-   oxidoreductase.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     mergedKcatList = mergeDLKcatAndFuzzyKcats(kcatListDLKcat, kcatListFuzzy);
    +     mergedKcatList = mergeDLKcatAndFuzzyKcats(kcatListDLKcat, kcatListFuzzy, 'wildcardLimit', 2);
    +
    + See also
    + --------
    + mergeKcats, readDLKcatOutput, fuzzyKcatMatching, assignKcatValues
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • mergeKcats mergeKcats Merge any number of kcatLists, keeping the highest-priority
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function mergedKcatList = mergeDLKcatAndFuzzyKcats(kcatListDLKcat, kcatListFuzzy, varargin)
    +0002 % mergeDLKcatAndFuzzyKcats  Merge DLKcat and BRENDA fuzzy matching results.
    +0003 %
    +0004 % Deprecated thin wrapper around mergeKcats, kept for the common DLKcat +
    +0005 % fuzzy-BRENDA case. New code should call mergeKcats directly, which also
    +0006 % handles a single list that mixes several sources (e.g. an
    +0007 % OpenKineticsPredictor result with BRENDA/Sabio-RK/CataPro rows).
    +0008 %
    +0009 % Merges the results from DLKcat and fuzzy matching to the BRENDA database.
    +0010 % Order of preference:
    +0011 %
    +0012 % 1. BRENDA match with correct E.C. number, with origin (see below) not
    +0013 %    lower than the specified topOriginLimit.
    +0014 % 2. DLKcat match.
    +0015 % 3. BRENDA match with correct E.C. number, with origin below topOriginLimit
    +0016 %    but not lower than the bottomOriginLimit.
    +0017 % 4. BRENDA match with wildcards in the E.C. number, with not more wildcards
    +0018 %    than wildcardLimit, and origin not lower than the bottomOriginLimit.
    +0019 %
    +0020 % Parameters
    +0021 % ----------
    +0022 % kcatListDLKcat : struct
    +0023 %     kcatList derived from readDLKcatOutput.
    +0024 % kcatListFuzzy : struct
    +0025 %     kcatList derived from fuzzyKcatMatching.
    +0026 %
    +0027 % Name-Value Arguments
    +0028 % --------------------
    +0029 % topOriginLimit : double
    +0030 %     origin limit for prioritized BRENDA matches. Origin is explained in
    +0031 %     more detail below (default 4: BRENDA matches of origin 5 and 6, from
    +0032 %     specific activities, rank after DLKcat; use 6 to rank them above).
    +0033 % bottomOriginLimit : double
    +0034 %     origin limit for low priority BRENDA matches. Origin is explained in
    +0035 %     more detail below (default 6).
    +0036 % wildcardLimit : double
    +0037 %     maximum number of wildcards in E.C. number of BRENDA matches
    +0038 %     (default 3).
    +0039 %
    +0040 % Returns
    +0041 % -------
    +0042 % mergedKcatList : struct
    +0043 %     merged kcatList with the same field layout produced by mergeKcats
    +0044 %     (source, kcatSource, rxns, genes, substrates, kcats, eccodes,
    +0045 %     wildcardLvl, origin), keeping only the rows selected by the order of
    +0046 %     preference above.
    +0047 %
    +0048 % Notes
    +0049 % -----
    +0050 % The origin parameter:
    +0051 %
    +0052 % - 1 : correct organism, correct substrate, kcat.
    +0053 % - 2 : any organism, correct substrate, kcat.
    +0054 % - 3 : correct organism, any substrate, kcat.
    +0055 % - 4 : any organism, any substrate, kcat.
    +0056 % - 5 : correct organism, specific activity.
    +0057 % - 6 : any organism, specific activity.
    +0058 %
    +0059 % Example of wildcards in E.C. number:
    +0060 %
    +0061 % - 0 : 1.1.1.3   glycerol-3-phosphate dehydrogenase (NAD+).
    +0062 % - 1 : 1.1.1.-   oxidoreductase, acting on the CH-OH group of donors, with
    +0063 %   NAD+ or NADP+ as acceptor.
    +0064 % - 2 : 1.1.-.-   oxidoreductase, acting on the CH-OH group of donors.
    +0065 % - 3 : 1.-.-.-   oxidoreductase.
    +0066 %
    +0067 % Examples
    +0068 % --------
    +0069 %     % optional arguments may be given positionally or as name-value pairs:
    +0070 %     mergedKcatList = mergeDLKcatAndFuzzyKcats(kcatListDLKcat, kcatListFuzzy);
    +0071 %     mergedKcatList = mergeDLKcatAndFuzzyKcats(kcatListDLKcat, kcatListFuzzy, 'wildcardLimit', 2);
    +0072 %
    +0073 % See also
    +0074 % --------
    +0075 % mergeKcats, readDLKcatOutput, fuzzyKcatMatching, assignKcatValues
    +0076 
    +0077 p = parseGECKOargs(varargin, { ...
    +0078     'topOriginLimit',    4; ...
    +0079     'bottomOriginLimit', 6; ...
    +0080     'wildcardLimit',     3});
    +0081 topOriginLimit    = p.topOriginLimit;
    +0082 bottomOriginLimit = p.bottomOriginLimit;
    +0083 wildcardLimit     = p.wildcardLimit;
    +0084 
    +0085 warning(['mergeDLKcatAndFuzzyKcats is deprecated; use mergeKcats instead. ' ...
    +0086     'The old name will be removed in a future release.']);
    +0087 
    +0088 % Fuzzy list first, then DLKcat, so surviving rows keep the legacy order
    +0089 % (fuzzy block followed by DLKcat block).
    +0090 mergedKcatList = mergeKcats({kcatListFuzzy, kcatListDLKcat}, ...
    +0091     {'database_top', 'dlkcat', 'database_bottom'}, ...
    +0092     'topOriginLimit', topOriginLimit, ...
    +0093     'bottomOriginLimit', bottomOriginLimit, ...
    +0094     'wildcardLimit', wildcardLimit);
    +0095 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/mergeKcats.html b/doc/src/gather_kcats/mergeKcats.html new file mode 100644 index 00000000..38643a3f --- /dev/null +++ b/doc/src/gather_kcats/mergeKcats.html @@ -0,0 +1,414 @@ + + + + Description of mergeKcats + + + + + + + + + +
    Home > src > gather_kcats > mergeKcats.m
    + + + +

    mergeKcats +

    + +

    PURPOSE ^

    +
    mergeKcats Merge any number of kcatLists, keeping the highest-priority
    + +

    SYNOPSIS ^

    +
    function mergedKcatList = mergeKcats(kcatLists, sourcePriority, varargin)
    + +

    DESCRIPTION ^

    +
     mergeKcats  Merge any number of kcatLists, keeping the highest-priority
    + source for each reaction.
    +
    + Generalizes mergeDLKcatAndFuzzyKcats: instead of two fixed inputs (DLKcat
    + + fuzzy BRENDA) it accepts a cell array of kcatLists, each of which may
    + itself mix several sources (for example the output of
    + fetchOpenKineticsPredictor, carrying BRENDA, Sabio-RK and CataPro values
    + in its kcatSource field). A caller-supplied sourcePriority decides which
    + source wins for each reaction.
    +
    + Parameters
    + ----------
    + kcatLists : cell
    +     cell array of kcatList structs (as produced by fuzzyKcatMatching,
    +     readDLKcatOutput, fetchOpenKineticsPredictor, ...).
    + sourcePriority : cell
    +     cell array of tier tokens / source labels, best first. Three
    +     reserved tier tokens may be used instead of a literal source label:
    +
    +     - 'database_exact'  an exact experimental-database measurement
    +       (a BRENDA/Sabio-RK row with no fuzzy metadata, i.e. a direct OKP
    +       hit, no wildcards).
    +     - 'database_top'    a fuzzy BRENDA match with wildcardLvl==0 and
    +       origin<=topOriginLimit.
    +     - 'database_bottom' weaker fuzzy BRENDA matches within
    +       wildcardLimit / bottomOriginLimit.
    +
    +     Any other token is matched against each row's source after folding
    +     to lowercase snake_case (e.g. 'dlkcat', 'catapro'). Sources not
    +     listed are dropped.
    +
    + Name-Value Arguments
    + --------------------
    + topOriginLimit : double
    +     origin limit for database_top (default 4). Origins 5 and 6 are specific
    +     activity times molecular weight kcats, which do not always beat a
    +     prediction; they rank after the other sources and are used where
    +     nothing else exists, or above DLKcat with topOriginLimit 6.
    + bottomOriginLimit : double
    +     origin limit for database_bottom (default 6).
    + wildcardLimit : double
    +     maximum wildcards for database_bottom's wildcard branch (default 3).
    + databaseSources : cell
    +     source labels treated as experimental databases, i.e. routed to the
    +     database_* tiers (default {'brenda','sabio_rk'}).
    +
    + Returns
    + -------
    + mergedKcatList : struct
    +     merged kcatList, keeping only the winning rows per reaction; see
    +     Notes below for its fields. Row order follows the order of the input
    +     lists (each list's surviving rows, in turn), so a two-list call
    +     behaves like the legacy mergeDLKcatAndFuzzyKcats.
    +
    + Notes
    + -----
    + The mergedKcatList structure has the following fields:
    +
    + - source : 'merged'.
    + - kcatSource : per-row provenance, preserved verbatim from the input
    +   lists.
    + - rxns : reaction identifiers.
    + - genes : gene identifiers (where provided by the input lists).
    + - substrates : substrate names (where provided by the input lists).
    + - kcats : selected kcat value in /sec.
    + - eccodes : as used to query BRENDA (where applicable).
    + - wildcardLvl : wildcard level of the source match (where applicable).
    + - origin : specificity level of the source match (where applicable).
    +
    + The origin parameter:
    +
    + - 1 : correct organism, correct substrate, kcat.
    + - 2 : any organism, correct substrate, kcat.
    + - 3 : correct organism, any substrate, kcat.
    + - 4 : any organism, any substrate, kcat.
    + - 5 : correct organism, specific activity.
    + - 6 : any organism, specific activity.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     mergedKcatList = mergeKcats({kcatListFuzzy, kcatListDLKcat}, ...
    +         {'database_top', 'dlkcat', 'database_bottom'});
    +     mergedKcatList = mergeKcats({kcatListFuzzy, kcatListOKP}, ...
    +         {'database_exact', 'database_top', 'database_bottom'}, 'wildcardLimit', 2);
    +
    + See also
    + --------
    + mergeDLKcatAndFuzzyKcats, readDLKcatOutput, fuzzyKcatMatching, assignKcatValues
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • collectKcats collectKcats Decide one kcat per reaction from the kcat source files.
    • mergeDLKcatAndFuzzyKcats mergeDLKcatAndFuzzyKcats Merge DLKcat and BRENDA fuzzy matching results.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function mergedKcatList = mergeKcats(kcatLists, sourcePriority, varargin)
    +0002 % mergeKcats  Merge any number of kcatLists, keeping the highest-priority
    +0003 % source for each reaction.
    +0004 %
    +0005 % Generalizes mergeDLKcatAndFuzzyKcats: instead of two fixed inputs (DLKcat
    +0006 % + fuzzy BRENDA) it accepts a cell array of kcatLists, each of which may
    +0007 % itself mix several sources (for example the output of
    +0008 % fetchOpenKineticsPredictor, carrying BRENDA, Sabio-RK and CataPro values
    +0009 % in its kcatSource field). A caller-supplied sourcePriority decides which
    +0010 % source wins for each reaction.
    +0011 %
    +0012 % Parameters
    +0013 % ----------
    +0014 % kcatLists : cell
    +0015 %     cell array of kcatList structs (as produced by fuzzyKcatMatching,
    +0016 %     readDLKcatOutput, fetchOpenKineticsPredictor, ...).
    +0017 % sourcePriority : cell
    +0018 %     cell array of tier tokens / source labels, best first. Three
    +0019 %     reserved tier tokens may be used instead of a literal source label:
    +0020 %
    +0021 %     - 'database_exact'  an exact experimental-database measurement
    +0022 %       (a BRENDA/Sabio-RK row with no fuzzy metadata, i.e. a direct OKP
    +0023 %       hit, no wildcards).
    +0024 %     - 'database_top'    a fuzzy BRENDA match with wildcardLvl==0 and
    +0025 %       origin<=topOriginLimit.
    +0026 %     - 'database_bottom' weaker fuzzy BRENDA matches within
    +0027 %       wildcardLimit / bottomOriginLimit.
    +0028 %
    +0029 %     Any other token is matched against each row's source after folding
    +0030 %     to lowercase snake_case (e.g. 'dlkcat', 'catapro'). Sources not
    +0031 %     listed are dropped.
    +0032 %
    +0033 % Name-Value Arguments
    +0034 % --------------------
    +0035 % topOriginLimit : double
    +0036 %     origin limit for database_top (default 4). Origins 5 and 6 are specific
    +0037 %     activity times molecular weight kcats, which do not always beat a
    +0038 %     prediction; they rank after the other sources and are used where
    +0039 %     nothing else exists, or above DLKcat with topOriginLimit 6.
    +0040 % bottomOriginLimit : double
    +0041 %     origin limit for database_bottom (default 6).
    +0042 % wildcardLimit : double
    +0043 %     maximum wildcards for database_bottom's wildcard branch (default 3).
    +0044 % databaseSources : cell
    +0045 %     source labels treated as experimental databases, i.e. routed to the
    +0046 %     database_* tiers (default {'brenda','sabio_rk'}).
    +0047 %
    +0048 % Returns
    +0049 % -------
    +0050 % mergedKcatList : struct
    +0051 %     merged kcatList, keeping only the winning rows per reaction; see
    +0052 %     Notes below for its fields. Row order follows the order of the input
    +0053 %     lists (each list's surviving rows, in turn), so a two-list call
    +0054 %     behaves like the legacy mergeDLKcatAndFuzzyKcats.
    +0055 %
    +0056 % Notes
    +0057 % -----
    +0058 % The mergedKcatList structure has the following fields:
    +0059 %
    +0060 % - source : 'merged'.
    +0061 % - kcatSource : per-row provenance, preserved verbatim from the input
    +0062 %   lists.
    +0063 % - rxns : reaction identifiers.
    +0064 % - genes : gene identifiers (where provided by the input lists).
    +0065 % - substrates : substrate names (where provided by the input lists).
    +0066 % - kcats : selected kcat value in /sec.
    +0067 % - eccodes : as used to query BRENDA (where applicable).
    +0068 % - wildcardLvl : wildcard level of the source match (where applicable).
    +0069 % - origin : specificity level of the source match (where applicable).
    +0070 %
    +0071 % The origin parameter:
    +0072 %
    +0073 % - 1 : correct organism, correct substrate, kcat.
    +0074 % - 2 : any organism, correct substrate, kcat.
    +0075 % - 3 : correct organism, any substrate, kcat.
    +0076 % - 4 : any organism, any substrate, kcat.
    +0077 % - 5 : correct organism, specific activity.
    +0078 % - 6 : any organism, specific activity.
    +0079 %
    +0080 % Examples
    +0081 % --------
    +0082 %     % optional arguments may be given positionally or as name-value pairs:
    +0083 %     mergedKcatList = mergeKcats({kcatListFuzzy, kcatListDLKcat}, ...
    +0084 %         {'database_top', 'dlkcat', 'database_bottom'});
    +0085 %     mergedKcatList = mergeKcats({kcatListFuzzy, kcatListOKP}, ...
    +0086 %         {'database_exact', 'database_top', 'database_bottom'}, 'wildcardLimit', 2);
    +0087 %
    +0088 % See also
    +0089 % --------
    +0090 % mergeDLKcatAndFuzzyKcats, readDLKcatOutput, fuzzyKcatMatching, assignKcatValues
    +0091 
    +0092 p = parseGECKOargs(varargin, { ...
    +0093     'topOriginLimit',    4; ...
    +0094     'bottomOriginLimit', 6; ...
    +0095     'wildcardLimit',     3; ...
    +0096     'databaseSources',   {'brenda','sabio_rk'}});
    +0097 topOriginLimit    = p.topOriginLimit;
    +0098 bottomOriginLimit = p.bottomOriginLimit;
    +0099 wildcardLimit     = p.wildcardLimit;
    +0100 databaseSources   = p.databaseSources;
    +0101 
    +0102 if (topOriginLimit < 1) || (topOriginLimit > 6)
    +0103     error('topOriginLimit should be between 1 and 6.');
    +0104 end
    +0105 if (bottomOriginLimit < 1) || (bottomOriginLimit > 6)
    +0106     error('bottomOriginLimit should be between 1 and 6.');
    +0107 end
    +0108 if (wildcardLimit < 0) || (wildcardLimit > 3)
    +0109     error('wildcardLimit should be between 0 and 3.');
    +0110 end
    +0111 if isempty(sourcePriority)
    +0112     error('sourcePriority must be a non-empty cell array.');
    +0113 end
    +0114 if ~iscell(kcatLists)
    +0115     error('kcatLists must be a cell array of kcatList structs.');
    +0116 end
    +0117 
    +0118 dbSources = cellfun(@normalizeSource, databaseSources, 'UniformOutput', false);
    +0119 
    +0120 % Rank map: normalised priority token -> rank (1 = best). First wins.
    +0121 rankMap = containers.Map('KeyType','char','ValueType','double');
    +0122 for r = 1:numel(sourcePriority)
    +0123     key = normalizeSource(sourcePriority{r});
    +0124     if ~isKey(rankMap, key)
    +0125         rankMap(key) = r;
    +0126     end
    +0127 end
    +0128 
    +0129 % Concatenate all lists, normalising missing fields per row.
    +0130 rxns = {}; kcats = []; genes = {}; substrates = {};
    +0131 eccodes = {}; wcl = []; origin = []; rawSource = {};
    +0132 for k = 1:numel(kcatLists)
    +0133     s = kcatLists{k};
    +0134     if isempty(s) || ~isfield(s,'rxns') || isempty(s.rxns)
    +0135         continue
    +0136     end
    +0137     n          = numel(s.rxns);
    +0138     rxns       = [rxns;       s.rxns(:)];
    +0139     kcats      = [kcats;      double(s.kcats(:))];
    +0140     genes      = [genes;      getColCell(s, 'genes', n)];
    +0141     substrates = [substrates; getColCell(s, 'substrates', n)];
    +0142     eccodes    = [eccodes;    getColCell(s, 'eccodes', n)];
    +0143     wcl        = [wcl;        getColNum(s, 'wildcardLvl', n)];
    +0144     origin     = [origin;     getColNum(s, 'origin', n)];
    +0145     rawSource  = [rawSource;  getRowSource(s, n)];
    +0146 end
    +0147 
    +0148 N = numel(rxns);
    +0149 if N == 0
    +0150     mergedKcatList = emptyMergedList();
    +0151     return
    +0152 end
    +0153 
    +0154 % Drop rows without a usable turnover number. This also removes the
    +0155 % kcats==0 rows fuzzyKcatMatching emits for unmatched reactions, so a
    +0156 % remaining NaN-metadata database row is unambiguously an exact OKP hit.
    +0157 valid          = kcats > 0;
    +0158 rxns           = rxns(valid);
    +0159 kcats          = kcats(valid);
    +0160 genes          = genes(valid);
    +0161 substrates     = substrates(valid);
    +0162 eccodes        = eccodes(valid);
    +0163 wcl            = wcl(valid);
    +0164 origin         = origin(valid);
    +0165 rawSource      = rawSource(valid);
    +0166 N              = numel(rxns);
    +0167 if N == 0
    +0168     mergedKcatList = emptyMergedList();
    +0169     return
    +0170 end
    +0171 
    +0172 token  = cellfun(@normalizeSource, rawSource, 'UniformOutput', false);
    +0173 isDb   = ismember(token, dbSources);
    +0174 hasMeta = ~isnan(wcl) & ~isnan(origin);
    +0175 
    +0176 % Tier per row ('' marks a database row that fails the quality gate).
    +0177 tier = token;
    +0178 dbIdx = find(isDb);
    +0179 for ii = dbIdx'
    +0180     if ~hasMeta(ii)
    +0181         tier{ii} = 'database_exact';
    +0182     elseif wcl(ii) == 0 && origin(ii) <= topOriginLimit
    +0183         tier{ii} = 'database_top';
    +0184     elseif (wcl(ii) == 0 && origin(ii) > topOriginLimit && origin(ii) <= bottomOriginLimit) || ...
    +0185            (wcl(ii) > 0  && wcl(ii) <= wildcardLimit       && origin(ii) <= bottomOriginLimit)
    +0186         tier{ii} = 'database_bottom';
    +0187     else
    +0188         tier{ii} = '';
    +0189     end
    +0190 end
    +0191 
    +0192 % Rank per row (NaN if the tier is not listed in sourcePriority).
    +0193 rankPerRow = nan(N,1);
    +0194 for ii = 1:N
    +0195     if ~isempty(tier{ii}) && isKey(rankMap, tier{ii})
    +0196         rankPerRow(ii) = rankMap(tier{ii});
    +0197     end
    +0198 end
    +0199 
    +0200 % Warn about non-database sources that were dropped for not being listed.
    +0201 droppedTokens = unique(token(~isDb & isnan(rankPerRow)));
    +0202 if ~isempty(droppedTokens)
    +0203     warning('Dropping rows from source(s) not listed in sourcePriority: %s', ...
    +0204         strjoin(droppedTokens', ', '));
    +0205 end
    +0206 
    +0207 % For each reaction keep all rows of its best (lowest-rank) tier.
    +0208 keep = false(N,1);
    +0209 validRank = ~isnan(rankPerRow);
    +0210 uRxns = unique(rxns(validRank));
    +0211 for k = 1:numel(uRxns)
    +0212     ri = find(strcmp(rxns, uRxns{k}) & validRank);
    +0213     minR = min(rankPerRow(ri));
    +0214     keep(ri(rankPerRow(ri) == minR)) = true;
    +0215 end
    +0216 
    +0217 mergedKcatList             = struct();
    +0218 mergedKcatList.source      = 'merged';
    +0219 mergedKcatList.kcatSource  = rawSource(keep);
    +0220 mergedKcatList.rxns        = rxns(keep);
    +0221 mergedKcatList.genes       = genes(keep);
    +0222 mergedKcatList.substrates  = substrates(keep);
    +0223 mergedKcatList.kcats       = kcats(keep);
    +0224 mergedKcatList.eccodes     = eccodes(keep);
    +0225 mergedKcatList.wildcardLvl = wcl(keep);
    +0226 mergedKcatList.origin      = origin(keep);
    +0227 end
    +0228 
    +0229 % ------------------------------------------------------------------------- %
    +0230 function s = normalizeSource(label)
    +0231 % Fold a source label to lowercase snake_case ('Sabio-RK' -> 'sabio_rk').
    +0232 s = lower(strtrim(char(label)));
    +0233 s = regexprep(s, '[^0-9a-z]+', '_');
    +0234 s = regexprep(s, '^_+|_+$', '');
    +0235 end
    +0236 
    +0237 function v = getColCell(s, name, n)
    +0238 if isfield(s, name) && ~isempty(s.(name))
    +0239     v = s.(name)(:);
    +0240     if numel(v) == 1 && n > 1
    +0241         v = repmat(v, n, 1);
    +0242     end
    +0243 else
    +0244     v = repmat({[]}, n, 1);
    +0245 end
    +0246 end
    +0247 
    +0248 function v = getColNum(s, name, n)
    +0249 if isfield(s, name) && ~isempty(s.(name))
    +0250     v = double(s.(name)(:));
    +0251 else
    +0252     v = nan(n, 1);
    +0253 end
    +0254 end
    +0255 
    +0256 function v = getRowSource(s, n)
    +0257 if isfield(s, 'kcatSource') && ~isempty(s.kcatSource)
    +0258     v = s.kcatSource(:);
    +0259 elseif isfield(s, 'source')
    +0260     v = repmat({char(s.source)}, n, 1);
    +0261 else
    +0262     v = repmat({''}, n, 1);
    +0263 end
    +0264 end
    +0265 
    +0266 function mergedKcatList = emptyMergedList()
    +0267 mergedKcatList             = struct();
    +0268 mergedKcatList.source      = 'merged';
    +0269 mergedKcatList.kcatSource  = {};
    +0270 mergedKcatList.rxns        = {};
    +0271 mergedKcatList.genes       = {};
    +0272 mergedKcatList.substrates  = {};
    +0273 mergedKcatList.kcats       = [];
    +0274 mergedKcatList.eccodes     = {};
    +0275 mergedKcatList.wildcardLvl = [];
    +0276 mergedKcatList.origin      = [];
    +0277 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/readDLKcatOutput.html b/doc/src/gather_kcats/readDLKcatOutput.html new file mode 100644 index 00000000..fa560d82 --- /dev/null +++ b/doc/src/gather_kcats/readDLKcatOutput.html @@ -0,0 +1,194 @@ + + + + Description of readDLKcatOutput + + + + + + + + + +
    Home > src > gather_kcats > readDLKcatOutput.m
    + + + +

    readDLKcatOutput +

    + +

    PURPOSE ^

    +
    readDLKcatOutput Read the DLKcat output file into a kcatList structure.
    + +

    SYNOPSIS ^

    +
    function kcatList = readDLKcatOutput(model, varargin)
    + +

    DESCRIPTION ^

    +
     readDLKcatOutput  Read the DLKcat output file into a kcatList structure.
    +
    + Reads the DLKcat output file and constructs a kcatList structure, that can
    + be used by assignKcatValues() to populate the ecModel with kcat values.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + outFile : char
    +     name and path of the DLKcat output file (default: data/DLKcat.tsv from
    +     the obj.params.path folder specified in the modelAdapter).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + kcatList : struct
    +     structure array with list of DLKcat derived kcat values, with separate
    +     entries for each kcat value.
    +
    + Notes
    + -----
    + The kcatList structure has the following fields:
    +
    + - source : 'DLKcat'.
    + - rxns : reaction identifiers.
    + - genes : gene identifiers.
    + - substrates : substrate names.
    + - kcats : predicted kcat value in /sec.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     kcatList = readDLKcatOutput(model);
    +     kcatList = readDLKcatOutput(model, 'outFile', 'myDLKcat.tsv');
    +
    + See also
    + --------
    + runDLKcat, writeDLKcatInput, assignKcatValues
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • kcatsFromDLKcat kcatsFromDLKcat Gather kcats from DLKcat and keep them as a source file.
    + + + + +

    SOURCE CODE ^

    +
    0001 function kcatList = readDLKcatOutput(model, varargin)
    +0002 % readDLKcatOutput  Read the DLKcat output file into a kcatList structure.
    +0003 %
    +0004 % Reads the DLKcat output file and constructs a kcatList structure, that can
    +0005 % be used by assignKcatValues() to populate the ecModel with kcat values.
    +0006 %
    +0007 % Parameters
    +0008 % ----------
    +0009 % model : struct
    +0010 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0011 %
    +0012 % Name-Value Arguments
    +0013 % --------------------
    +0014 % outFile : char
    +0015 %     name and path of the DLKcat output file (default: data/DLKcat.tsv from
    +0016 %     the obj.params.path folder specified in the modelAdapter).
    +0017 % modelAdapter : ModelAdapter
    +0018 %     a loaded model adapter (default: the current default model adapter).
    +0019 %
    +0020 % Returns
    +0021 % -------
    +0022 % kcatList : struct
    +0023 %     structure array with list of DLKcat derived kcat values, with separate
    +0024 %     entries for each kcat value.
    +0025 %
    +0026 % Notes
    +0027 % -----
    +0028 % The kcatList structure has the following fields:
    +0029 %
    +0030 % - source : 'DLKcat'.
    +0031 % - rxns : reaction identifiers.
    +0032 % - genes : gene identifiers.
    +0033 % - substrates : substrate names.
    +0034 % - kcats : predicted kcat value in /sec.
    +0035 %
    +0036 % Examples
    +0037 % --------
    +0038 %     % optional arguments may be given positionally or as name-value pairs:
    +0039 %     kcatList = readDLKcatOutput(model);
    +0040 %     kcatList = readDLKcatOutput(model, 'outFile', 'myDLKcat.tsv');
    +0041 %
    +0042 % See also
    +0043 % --------
    +0044 % runDLKcat, writeDLKcatInput, assignKcatValues
    +0045 
    +0046 p = parseGECKOargs(varargin, { ...
    +0047     'outFile',      []; ...
    +0048     'modelAdapter', []});
    +0049 outFile      = p.outFile;
    +0050 modelAdapter = p.modelAdapter;
    +0051 
    +0052 if isempty(modelAdapter)
    +0053     modelAdapter = ModelAdapterManager.getDefault();
    +0054     if isempty(modelAdapter)
    +0055         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0056     end
    +0057 end
    +0058 params = modelAdapter.params;
    +0059 
    +0060 if isempty(outFile)
    +0061     fID      = fopen(fullfile(params.path,'data','DLKcat.tsv'),'r');
    +0062 else
    +0063     fID      = fopen(outFile);
    +0064 end
    +0065 DLKcatOutput = textscan(fID,'%s %s %s %s %s %s','Delimiter','\t','HeaderLines',1);
    +0066 fclose(fID);
    +0067 
    +0068 % Check that DLKcat output file and model match (not fool proof, but good enough)
    +0069 [rxns, genes, subs, kcats] = deal(DLKcatOutput{[1,2,3,6]});
    +0070 
    +0071 % Check if it contains any kcat values
    +0072 if all(cellfun(@isempty,kcats)) || all(strcmpi(kcats,'NA'))
    +0073     error('DLKcat file does not contain any kcat values, please run runDLKcat() first.')
    +0074 end
    +0075 
    +0076 % Check that all substrates are in the model (case-insensitive: an SBML loader can
    +0077 % normalise metabolite-name capitalisation differently than whatever produced the
    +0078 % DLKcat input, and that must not read as a genuinely missing substrate).
    +0079 matchMets = ismember(lower(subs),lower(model.metNames));
    +0080 if ~all(matchMets)
    +0081     errorText = 'DLKcat was likely run with an input file that was generated from another ecModel, as the following substrates from DLKcat output cannot be found in model.metNames:';
    +0082     error('%s', ravenList(errorText,subs(~matchMets),false))
    +0083 end
    +0084 
    +0085 % Check that all reactions are in model.ec.rxns
    +0086 matchRxns = ismember(rxns,model.ec.rxns);
    +0087 if ~all(matchRxns)
    +0088     errorText = 'DLKcat was likely run with an input file that was generated from another ecModel, as the following reactions from DLKcat output cannot be found in model.metNames:';
    +0089     error('%s', ravenList(errorText,rxns(~matchRxns),false))
    +0090 end
    +0091 
    +0092 % Filter out entries with no numeric value
    +0093 noOutput        = cellfun(@isempty,regexpi(kcats,'[0-9]'));
    +0094 kcats           = str2double(kcats(~noOutput));
    +0095 rxns(noOutput)  = [];
    +0096 genes(noOutput) = [];
    +0097 subs(noOutput)  = [];
    +0098 
    +0099 % Make kcatList structure
    +0100 kcatList.source     = 'DLKcat';
    +0101 kcatList.rxns       = rxns;
    +0102 kcatList.genes      = genes;
    +0103 kcatList.substrates = subs;
    +0104 kcatList.kcats      = kcats;
    +0105 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/readOpenKineticsPredictorOutput.html b/doc/src/gather_kcats/readOpenKineticsPredictorOutput.html new file mode 100644 index 00000000..42a93a28 --- /dev/null +++ b/doc/src/gather_kcats/readOpenKineticsPredictorOutput.html @@ -0,0 +1,409 @@ + + + + Description of readOpenKineticsPredictorOutput + + + + + + + + + +
    Home > src > gather_kcats > readOpenKineticsPredictorOutput.m
    + + + +

    readOpenKineticsPredictorOutput +

    + +

    PURPOSE ^

    +
    readOpenKineticsPredictorOutput Read OpenKineticsPredictor output to kcatList.
    + +

    SYNOPSIS ^

    +
    function kcatList = readOpenKineticsPredictorOutput(model, varargin)
    + +

    DESCRIPTION ^

    +
     readOpenKineticsPredictorOutput  Read OpenKineticsPredictor output to kcatList.
    +
    + Reads the OpenKineticsPredictor output file (job-*-output.csv with columns:
    + kcat (1/s), Source kcat, Extra Info kcat, Protein Sequence, Substrate) and
    + constructs a kcatList structure, that can be used by assignKcatValues() to
    + populate the ecModel with kcat values.
    +
    + CatRange predicts a class of kcat values, which OKP returns as its range
    + (for instance '10 to 100 s^-1'). It is read as the geometric midpoint of
    + the range, or half the upper bound for the class starting at 0.
    +
    + The per-entry `Source kcat` column (e.g. 'Prediction from CatPred',
    + 'BRENDA', 'Sabio-RK', 'UniProt') is preserved in kcatList.kcatSource so
    + that assignKcatValues() records the actual provenance of each value.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + outFile : char
    +     name and path of the OpenKineticsPredictor output CSV. If omitted, a
    +     file selection dialog is opened, starting in the data/ folder specified
    +     by the modelAdapter.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + kcatList : struct
    +     structure array with list of kcat values from OpenKineticsPredictor,
    +     with separate entries for each kcat value.
    +
    + Notes
    + -----
    + The kcatList structure has the following fields:
    +
    + - source : 'OpenKineticsPredictor'.
    + - rxns : reaction identifiers, matching model.ec.rxns.
    + - genes : gene identifiers, matching model.ec.genes.
    + - substrates : substrate names, matching model.metNames.
    + - kcats : kcat values in /sec.
    + - similarity : the enzyme's highest sequence similarity to the method's
    +   training data, in percent (NaN without the similarity column)
    + - kcatSource : per-entry source as reported by OKP, prefixed with 'OKP-'
    +   (e.g. 'OKP-CatPred', 'OKP-BRENDA', 'OKP-Sabio-RK', 'OKP-UniProt').
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     kcatList = readOpenKineticsPredictorOutput(model);
    +     kcatList = readOpenKineticsPredictorOutput(model, 'outFile', 'job-output.csv');
    +
    + See also
    + --------
    + writeOpenKineticsPredictorInput, assignKcatValues
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • fetchOpenKineticsPredictor fetchOpenKineticsPredictor Fetch and parse an OpenKineticsPredictor job.
    • kcatsFromOKP kcatsFromOKP Gather kcats from OpenKineticsPredictor and keep them as a source file.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function kcatList = readOpenKineticsPredictorOutput(model, varargin)
    +0002 % readOpenKineticsPredictorOutput  Read OpenKineticsPredictor output to kcatList.
    +0003 %
    +0004 % Reads the OpenKineticsPredictor output file (job-*-output.csv with columns:
    +0005 % kcat (1/s), Source kcat, Extra Info kcat, Protein Sequence, Substrate) and
    +0006 % constructs a kcatList structure, that can be used by assignKcatValues() to
    +0007 % populate the ecModel with kcat values.
    +0008 %
    +0009 % CatRange predicts a class of kcat values, which OKP returns as its range
    +0010 % (for instance '10 to 100 s^-1'). It is read as the geometric midpoint of
    +0011 % the range, or half the upper bound for the class starting at 0.
    +0012 %
    +0013 % The per-entry `Source kcat` column (e.g. 'Prediction from CatPred',
    +0014 % 'BRENDA', 'Sabio-RK', 'UniProt') is preserved in kcatList.kcatSource so
    +0015 % that assignKcatValues() records the actual provenance of each value.
    +0016 %
    +0017 % Parameters
    +0018 % ----------
    +0019 % model : struct
    +0020 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0021 %
    +0022 % Name-Value Arguments
    +0023 % --------------------
    +0024 % outFile : char
    +0025 %     name and path of the OpenKineticsPredictor output CSV. If omitted, a
    +0026 %     file selection dialog is opened, starting in the data/ folder specified
    +0027 %     by the modelAdapter.
    +0028 % modelAdapter : ModelAdapter
    +0029 %     a loaded model adapter (default: the current default model adapter).
    +0030 %
    +0031 % Returns
    +0032 % -------
    +0033 % kcatList : struct
    +0034 %     structure array with list of kcat values from OpenKineticsPredictor,
    +0035 %     with separate entries for each kcat value.
    +0036 %
    +0037 % Notes
    +0038 % -----
    +0039 % The kcatList structure has the following fields:
    +0040 %
    +0041 % - source : 'OpenKineticsPredictor'.
    +0042 % - rxns : reaction identifiers, matching model.ec.rxns.
    +0043 % - genes : gene identifiers, matching model.ec.genes.
    +0044 % - substrates : substrate names, matching model.metNames.
    +0045 % - kcats : kcat values in /sec.
    +0046 % - similarity : the enzyme's highest sequence similarity to the method's
    +0047 %   training data, in percent (NaN without the similarity column)
    +0048 % - kcatSource : per-entry source as reported by OKP, prefixed with 'OKP-'
    +0049 %   (e.g. 'OKP-CatPred', 'OKP-BRENDA', 'OKP-Sabio-RK', 'OKP-UniProt').
    +0050 %
    +0051 % Examples
    +0052 % --------
    +0053 %     % optional arguments may be given positionally or as name-value pairs:
    +0054 %     kcatList = readOpenKineticsPredictorOutput(model);
    +0055 %     kcatList = readOpenKineticsPredictorOutput(model, 'outFile', 'job-output.csv');
    +0056 %
    +0057 % See also
    +0058 % --------
    +0059 % writeOpenKineticsPredictorInput, assignKcatValues
    +0060 
    +0061 p = parseGECKOargs(varargin, { ...
    +0062     'outFile',      []; ...
    +0063     'modelAdapter', []});
    +0064 outFile      = p.outFile;
    +0065 modelAdapter = p.modelAdapter;
    +0066 
    +0067 if isempty(modelAdapter)
    +0068     modelAdapter = ModelAdapterManager.getDefault();
    +0069     if isempty(modelAdapter)
    +0070         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0071     end
    +0072 end
    +0073 params = modelAdapter.params;
    +0074 
    +0075 if isempty(outFile)
    +0076     startDir = fullfile(params.path,'data');
    +0077     if ~exist(startDir,'dir')
    +0078         startDir = params.path;
    +0079     end
    +0080     [fName, fPath] = uigetfile({'*.csv','OpenKineticsPredictor output (*.csv)'; ...
    +0081                                 '*.*','All files (*.*)'}, ...
    +0082                                'Select OpenKineticsPredictor output file', ...
    +0083                                fullfile(startDir, filesep));
    +0084     if isequal(fName,0)
    +0085         error('No file selected.')
    +0086     end
    +0087     outFile = fullfile(fPath, fName);
    +0088 end
    +0089 
    +0090 %% Read OKP output file using readcell to correctly handle quoted fields
    +0091 % that may contain commas in the 'Extra Info kcat' column.
    +0092 if ~exist(outFile,'file')
    +0093     error('Cannot find file: %s', outFile)
    +0094 end
    +0095 raw = readcell(outFile, 'Delimiter', ',', 'TextType', 'char');
    +0096 
    +0097 if size(raw,2) < 5
    +0098     error('OKP output file does not have the expected 5 columns (kcat, Source kcat, Extra Info kcat, Protein Sequence, Substrate): %s', outFile)
    +0099 end
    +0100 
    +0101 % Drop header row; the 'max similarity to <method> training data' column,
    +0102 % when present, gives the similarity.
    +0103 header = cellfun(@(h) char(string(h)), raw(1,:), 'UniformOutput', false);
    +0104 simCol = find(startsWith(header, 'max similarity to'), 1);
    +0105 raw = raw(2:end, :);
    +0106 similarity = nan(size(raw, 1), 1);
    +0107 if ~isempty(simCol)
    +0108     for i = 1:size(raw, 1)
    +0109         v = raw{i, simCol};
    +0110         if isnumeric(v) && ~isempty(v)
    +0111             similarity(i) = v;
    +0112         elseif ischar(v) || isstring(v)
    +0113             similarity(i) = str2double(v);
    +0114         end
    +0115     end
    +0116 end
    +0117 
    +0118 kcatsCol      = raw(:,1);
    +0119 sourceKcatCol = raw(:,2);
    +0120 sequences     = raw(:,4);
    +0121 smiles        = raw(:,5);
    +0122 
    +0123 % Normalize types: readcell returns doubles for numeric cells, char for
    +0124 % strings, and `missing` for empty fields.
    +0125 kcats = nan(size(kcatsCol));
    +0126 for i = 1:numel(kcatsCol)
    +0127     v = kcatsCol{i};
    +0128     if isnumeric(v)
    +0129         kcats(i) = v;
    +0130     elseif ischar(v) || isstring(v)
    +0131         kcats(i) = kcatFromText(char(v));
    +0132     end
    +0133 end
    +0134 
    +0135 sourceKcatCol = normalizeCellStrings(sourceKcatCol);
    +0136 sequences     = normalizeCellStrings(sequences);
    +0137 smiles        = normalizeCellStrings(smiles);
    +0138 
    +0139 %% Filter out entries with no numeric kcat value (NaN). Zero values are
    +0140 % retained here and filtered downstream by assignKcatValues.
    +0141 valid = ~isnan(kcats);
    +0142 kcats         = kcats(valid);
    +0143 sequences     = sequences(valid);
    +0144 smiles        = smiles(valid);
    +0145 sourceKcatCol = sourceKcatCol(valid);
    +0146 similarity    = similarity(valid);
    +0147 
    +0148 if isempty(kcats)
    +0149     error('OKP file does not contain any numeric kcat values. Run the job at https://predictor.openkinetics.org/ first.')
    +0150 end
    +0151 
    +0152 if ~isfield(model,'metSmiles')
    +0153     error('model.metSmiles is required to map SMILES back to metabolites.')
    +0154 end
    +0155 
    +0156 %% Build ec.rxns -> model.rxns index mapping (inverse of the mapping done
    +0157 %  in writeOpenKineticsPredictorInput)
    +0158 if model.ec.geckoLight
    +0159     origRxns = extractAfter(model.ec.rxns, 4);
    +0160 else
    +0161     origRxns = model.ec.rxns;
    +0162 end
    +0163 [foundEcRxn, ecRxnToModelRxn] = ismember(origRxns, model.rxns);
    +0164 if ~all(foundEcRxn)
    +0165     error('Not all entries in model.ec.rxns could be matched to model.rxns.')
    +0166 end
    +0167 
    +0168 %% Resolve each row to matching ec.rxns indices
    +0169 rxnsOut       = cell(0,1);
    +0170 genesOut      = cell(0,1);
    +0171 substratesOut = cell(0,1);
    +0172 kcatsOut      = zeros(0,1);
    +0173 sourceOut     = cell(0,1);
    +0174 similarityOut = zeros(0,1);
    +0175 unmatched     = 0;
    +0176 
    +0177 for i = 1:numel(sequences)
    +0178     % Map protein sequence -> ec.genes indices (columns of rxnEnzMat)
    +0179     proteinIdxs = find(strcmp(model.ec.sequence, sequences{i}));
    +0180     % Map SMILES -> metabolite indices (rows of model.S)
    +0181     metIdxs = find(strcmp(model.metSmiles, smiles{i}));
    +0182 
    +0183     if isempty(proteinIdxs) || isempty(metIdxs)
    +0184         unmatched = unmatched + 1;
    +0185         continue
    +0186     end
    +0187 
    +0188     % model.rxns columns where any of these mets are substrates (S < 0)
    +0189     modelRxnsUsingSub = any(model.S(metIdxs, :) < 0, 1);
    +0190 
    +0191     % Lift to ec.rxns: does the underlying model.rxn consume this metabolite?
    +0192     ecRxnUsesSub = modelRxnsUsingSub(ecRxnToModelRxn).';
    +0193 
    +0194     % ec.rxns catalyzed by any of these protein(s)
    +0195     ecRxnCatalyzed = any(model.ec.rxnEnzMat(:, proteinIdxs) ~= 0, 2);
    +0196 
    +0197     candidateEcRxns = find(ecRxnUsesSub & ecRxnCatalyzed);
    +0198 
    +0199     if isempty(candidateEcRxns)
    +0200         unmatched = unmatched + 1;
    +0201         continue
    +0202     end
    +0203 
    +0204     for k = 1:numel(candidateEcRxns)
    +0205         ecIdx = candidateEcRxns(k);
    +0206 
    +0207         % Pick the gene whose protein both matches this sequence and
    +0208         % catalyzes this ec.rxn
    +0209         catalysts       = find(model.ec.rxnEnzMat(ecIdx, :) ~= 0);
    +0210         matchingProtein = intersect(proteinIdxs, catalysts, 'stable');
    +0211         if ~isempty(matchingProtein)
    +0212             geneName = model.ec.genes{matchingProtein(1)};
    +0213         else
    +0214             geneName = '';
    +0215         end
    +0216 
    +0217         % Pick a metabolite name whose SMILES matches and that is a
    +0218         % substrate of the underlying model.rxn
    +0219         origRxnIdx       = ecRxnToModelRxn(ecIdx);
    +0220         metIsSub         = model.S(metIdxs, origRxnIdx) < 0;
    +0221         substrateMetIdxs = metIdxs(metIsSub);
    +0222         if ~isempty(substrateMetIdxs)
    +0223             subName = model.metNames{substrateMetIdxs(1)};
    +0224         else
    +0225             subName = '';
    +0226         end
    +0227 
    +0228         rxnsOut{end+1,1}       = model.ec.rxns{ecIdx};
    +0229         genesOut{end+1,1}      = geneName;
    +0230         substratesOut{end+1,1} = subName;
    +0231         kcatsOut(end+1,1)      = kcats(i);
    +0232         sourceOut{end+1,1}     = sourceKcatCol{i};
    +0233         similarityOut(end+1,1) = similarity(i);
    +0234     end
    +0235 end
    +0236 
    +0237 if unmatched > 0
    +0238     warning('%d of %d OKP entries could not be matched to an ec.rxn (protein sequence and/or SMILES not found in model, or no enzyme+substrate pair matches).', ...
    +0239         unmatched, numel(sequences));
    +0240 end
    +0241 
    +0242 if isempty(rxnsOut)
    +0243     error('No OKP entries could be mapped to model.ec.rxns.')
    +0244 end
    +0245 
    +0246 %% Build per-entry source labels
    +0247 % Strip leading 'Prediction from ' to keep labels compact, then prefix all
    +0248 % with 'OKP-' so the overall pipeline stage is still identifiable in
    +0249 % model.ec.source.
    +0250 kcatSource = regexprep(sourceOut, '^Prediction from\s+', '');
    +0251 kcatSource = strcat('OKP-', kcatSource);
    +0252 
    +0253 %% Make kcatList structure
    +0254 kcatList.source     = 'OpenKineticsPredictor';
    +0255 kcatList.rxns       = rxnsOut;
    +0256 kcatList.genes      = genesOut;
    +0257 kcatList.substrates = substratesOut;
    +0258 kcatList.kcats      = kcatsOut;
    +0259 kcatList.kcatSource = kcatSource;
    +0260 kcatList.similarity = similarityOut;
    +0261 end
    +0262 
    +0263 function c = normalizeCellStrings(c)
    +0264 % Convert each cell entry to a char row vector; missing/empty -> ''.
    +0265 for i = 1:numel(c)
    +0266     v = c{i};
    +0267     if ismissing(v)
    +0268         c{i} = '';
    +0269     elseif isstring(v)
    +0270         c{i} = char(v);
    +0271     elseif isnumeric(v)
    +0272         if isnan(v)
    +0273             c{i} = '';
    +0274         else
    +0275             c{i} = num2str(v);
    +0276         end
    +0277     elseif ~ischar(v)
    +0278         c{i} = char(string(v));
    +0279     end
    +0280 end
    +0281 end
    +0282 
    +0283 function kcat = kcatFromText(v)
    +0284 % A number, or a CatRange class range '<low> to <high> s^-1' as its
    +0285 % geometric midpoint (half the upper bound when the class starts at 0).
    +0286 kcat = str2double(v);
    +0287 if ~isnan(kcat)
    +0288     return
    +0289 end
    +0290 bounds = regexp(strtrim(v), '^([0-9.eE+-]+)\s+to\s+([0-9.eE+-]+)(\s*s\^-1)?$', 'tokens', 'once');
    +0291 if isempty(bounds)
    +0292     return
    +0293 end
    +0294 low = str2double(bounds{1});
    +0295 high = str2double(bounds{2});
    +0296 if isnan(low) || isnan(high)
    +0297     return
    +0298 elseif low > 0
    +0299     kcat = sqrt(low * high);
    +0300 else
    +0301     kcat = high / 2;
    +0302 end
    +0303 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/removeStandardKcat.html b/doc/src/gather_kcats/removeStandardKcat.html new file mode 100644 index 00000000..8d64a4c9 --- /dev/null +++ b/doc/src/gather_kcats/removeStandardKcat.html @@ -0,0 +1,143 @@ + + + + Description of removeStandardKcat + + + + + + + + + +
    Home > src > gather_kcats > removeStandardKcat.m
    + + + +

    removeStandardKcat +

    + +

    PURPOSE ^

    +
    removeStandardKcat Remove the standard pseudoenzyme and standard kcats.
    + +

    SYNOPSIS ^

    +
    function model = removeStandardKcat(model)
    + +

    DESCRIPTION ^

    +
     removeStandardKcat  Remove the standard pseudoenzyme and standard kcats.
    +
    + Removes the "standard" pseudoenzyme and standard kcat and MW values, as
    + they were introduced by getStandardKcat. Also standard kcat values that
    + were assigned by getStandardKcat if fillZeroKcat was set to true are
    + removed from model.ec.kcat. Both the model.ec and model.S structures are
    + modified.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure) that has
    +     standard kcat values implemented by getStandardKcat.
    +
    + Returns
    + -------
    + model : struct
    +     ecModel without standard pseudoprotein and standard kcat values.
    +
    + Examples
    + --------
    +     model = removeStandardKcat(model);
    +
    + See also
    + --------
    + getStandardKcat, applyKcatConstraints
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function model = removeStandardKcat(model)
    +0002 % removeStandardKcat  Remove the standard pseudoenzyme and standard kcats.
    +0003 %
    +0004 % Removes the "standard" pseudoenzyme and standard kcat and MW values, as
    +0005 % they were introduced by getStandardKcat. Also standard kcat values that
    +0006 % were assigned by getStandardKcat if fillZeroKcat was set to true are
    +0007 % removed from model.ec.kcat. Both the model.ec and model.S structures are
    +0008 % modified.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % model : struct
    +0013 %     an ecModel in GECKO 3 format (with ecModel.ec structure) that has
    +0014 %     standard kcat values implemented by getStandardKcat.
    +0015 %
    +0016 % Returns
    +0017 % -------
    +0018 % model : struct
    +0019 %     ecModel without standard pseudoprotein and standard kcat values.
    +0020 %
    +0021 % Examples
    +0022 % --------
    +0023 %     model = removeStandardKcat(model);
    +0024 %
    +0025 % See also
    +0026 % --------
    +0027 % getStandardKcat, applyKcatConstraints
    +0028 
    +0029 % Remove standard enzyme from ec structure
    +0030 stdEnzIdx = find(strcmpi(model.ec.enzymes, 'standard'));
    +0031 if ~isempty(stdEnzIdx)
    +0032     model.ec.genes(stdEnzIdx)       = [];
    +0033     model.ec.enzymes(stdEnzIdx)     = [];
    +0034     model.ec.mw(stdEnzIdx)          = [];
    +0035     model.ec.sequence(stdEnzIdx)    = [];
    +0036     if isfield(model.ec,'concs')
    +0037         model.ec.concs(stdEnzIdx)   = [];
    +0038     end
    +0039     rxnEnzIdx = find(model.ec.rxnEnzMat(:,stdEnzIdx));
    +0040     model.ec.rxns(rxnEnzIdx)        = [];
    +0041     model.ec.kcat(rxnEnzIdx)        = [];
    +0042     model.ec.source(rxnEnzIdx)      = [];
    +0043     model.ec.notes(rxnEnzIdx)       = [];
    +0044     model.ec.eccodes(rxnEnzIdx)     = [];
    +0045     model.ec.rxnEnzMat(:,stdEnzIdx) = [];
    +0046     model.ec.rxnEnzMat(rxnEnzIdx,:) = [];
    +0047 end
    +0048 
    +0049 % Remove standard kcat values and reapply kcat constraints for those
    +0050 % specific reactions
    +0051 stdKcatIdx = find(strcmpi(model.ec.source, 'standard'));
    +0052 if ~isempty(stdKcatIdx)
    +0053     model.ec.source(stdKcatIdx)     = {''};
    +0054     model.ec.kcat(stdKcatIdx)       = 0;
    +0055     model = applyKcatConstraints(model,stdKcatIdx);
    +0056 end
    +0057 
    +0058 % Remove standard protein, usage and gene from model structure
    +0059 stdMetIdx = find(strcmpi(model.mets, 'prot_standard'));
    +0060 if ~isempty(stdMetIdx)
    +0061     model       = removeMets(model,stdMetIdx,false,false,false,false);
    +0062 end
    +0063 stdProtEx = find(strcmpi(model.rxns, 'usage_prot_standard'));
    +0064 if ~isempty(stdProtEx)
    +0065     model       = removeReactions(model,stdProtEx,false,false,false);
    +0066 end
    +0067 stdProtGene = find(strcmpi(model.genes, 'standard'));
    +0068 if ~isempty(stdProtGene)
    +0069     model       = removeGenes(model,stdProtGene,false,false,false);
    +0070 end
    +0071 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/resolveOkpApiKey.html b/doc/src/gather_kcats/resolveOkpApiKey.html new file mode 100644 index 00000000..7a35b449 --- /dev/null +++ b/doc/src/gather_kcats/resolveOkpApiKey.html @@ -0,0 +1,120 @@ + + + + Description of resolveOkpApiKey + + + + + + + + + +
    Home > src > gather_kcats > resolveOkpApiKey.m
    + + + +

    resolveOkpApiKey +

    + +

    PURPOSE ^

    +
    resolveOkpApiKey Resolve the OpenKineticsPredictor API key.
    + +

    SYNOPSIS ^

    +
    function key = resolveOkpApiKey(argKey, basePath)
    + +

    DESCRIPTION ^

    +
     resolveOkpApiKey  Resolve the OpenKineticsPredictor API key.
    +
    + Internal helper shared by submitOpenKineticsPredictor and
    + fetchOpenKineticsPredictor; not intended to be called directly.
    +
    + Checked in order: the argKey input, the OKP_API_KEY environment variable,
    + then a plain-text file data/okpApiKey.txt under basePath (this name is
    + git-ignored by GECKO). The key is a secret and must never be read from the
    + model adapter, which is shared/committed.
    +
    + Parameters
    + ----------
    + argKey : char
    +     an explicitly provided key, or empty to fall through to the
    +     environment variable / file.
    + basePath : char
    +     the model adapter's params.path, under which data/okpApiKey.txt is
    +     looked up.
    +
    + Returns
    + -------
    + key : char
    +     the resolved API key.
    +
    + See also
    + --------
    + submitOpenKineticsPredictor, fetchOpenKineticsPredictor
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: + + + + + +

    SOURCE CODE ^

    +
    0001 function key = resolveOkpApiKey(argKey, basePath)
    +0002 % resolveOkpApiKey  Resolve the OpenKineticsPredictor API key.
    +0003 %
    +0004 % Internal helper shared by submitOpenKineticsPredictor and
    +0005 % fetchOpenKineticsPredictor; not intended to be called directly.
    +0006 %
    +0007 % Checked in order: the argKey input, the OKP_API_KEY environment variable,
    +0008 % then a plain-text file data/okpApiKey.txt under basePath (this name is
    +0009 % git-ignored by GECKO). The key is a secret and must never be read from the
    +0010 % model adapter, which is shared/committed.
    +0011 %
    +0012 % Parameters
    +0013 % ----------
    +0014 % argKey : char
    +0015 %     an explicitly provided key, or empty to fall through to the
    +0016 %     environment variable / file.
    +0017 % basePath : char
    +0018 %     the model adapter's params.path, under which data/okpApiKey.txt is
    +0019 %     looked up.
    +0020 %
    +0021 % Returns
    +0022 % -------
    +0023 % key : char
    +0024 %     the resolved API key.
    +0025 %
    +0026 % See also
    +0027 % --------
    +0028 % submitOpenKineticsPredictor, fetchOpenKineticsPredictor
    +0029 
    +0030 if ~isempty(argKey)
    +0031     key = strtrim(char(argKey));
    +0032     return
    +0033 end
    +0034 envKey = getenv('OKP_API_KEY');
    +0035 if ~isempty(envKey)
    +0036     key = strtrim(envKey);
    +0037     return
    +0038 end
    +0039 keyFile = fullfile(basePath,'data','okpApiKey.txt');
    +0040 if exist(keyFile,'file')
    +0041     key = strtrim(fileread(keyFile));
    +0042     return
    +0043 end
    +0044 error(['No OpenKineticsPredictor API key found. Provide it as the apiKey ' ...
    +0045        'argument, set the OKP_API_KEY environment variable, or place it in ' ...
    +0046        '%s. Generate a key at https://predictor.openkinetics.org/.'], keyFile);
    +0047 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/reviewKcatAssignment.html b/doc/src/gather_kcats/reviewKcatAssignment.html new file mode 100644 index 00000000..ac356f8d --- /dev/null +++ b/doc/src/gather_kcats/reviewKcatAssignment.html @@ -0,0 +1,396 @@ + + + + Description of reviewKcatAssignment + + + + + + + + + +
    Home > src > gather_kcats > reviewKcatAssignment.m
    + + + +

    reviewKcatAssignment +

    + +

    PURPOSE ^

    +
    reviewKcatAssignment Flag kcat assignments that deserve a second look.
    + +

    SYNOPSIS ^

    +
    function findings = reviewKcatAssignment(rxnIds,kcats,sources,ecCodes,varargin)
    + +

    DESCRIPTION ^

    +
     reviewKcatAssignment  Flag kcat assignments that deserve a second look.
    +
    + A tuner's largest corrections are rarely discoveries about biology.
    + They are places the assignment went wrong: a value derived from one
    + specific-activity measurement, a database maximum standing in for a
    + distribution with a two-hundred-fold spread, one fallback number reused
    + across a whole family of reactions. Finding those directly is cheaper
    + than inferring them from a fit, and a corrected prior propagates to
    + every model built from the same databases, where a tuned kcat stays in
    + the model it was tuned on.
    +
    + Two design choices, both from measurement rather than taste (see
    + geckopy's gather_kcats/review.py, which this ports):
    +
    + Rank by leverage, and cut the report there. Tightening the checks
    + themselves does not shorten a report nearly as well, because looking
    + odd and mattering are unrelated properties. Filtering by leverage keeps
    + the list short and keeps the entries worth a curator's time.
    +
    + Report a parameter once. Isozyme copies the assignment could not
    + separate share a value and a source, so they share a finding; listing
    + them separately fills the report with duplicates of one decision.
    +
    + Parameters
    + ----------
    + rxnIds, kcats, sources, ecCodes : cell/double
    +     ec.rxns, ec.kcat, ec.source, ec.eccodes (or the equivalent
    +     subset), all the same length.
    +
    + Name-Value Arguments
    + --------------------
    + ecStats : containers.Map
    +     EC code -> struct(nKcat,kcatMax,kcatMedian,values,nSa), as returned
    +     by ecStatsFromBrenda. Checks needing it are skipped when it is
    +     absent, so this still runs without a database.
    + enzymes : cell
    +     protein ids per kcat (cell of cell arrays), used to count how many
    +     other reactions share an enzyme.
    + names : cell
    +     reaction names, same length as rxnIds (default: not shown).
    + leverage : double
    +     per-kcat effect on the distance from a one-at-a-time screen (e.g.
    +     screenKcatLeverage's leverage column, expanded back to
    +     ecModel.ec.rxns positions). Without it findings cannot be ranked
    +     and are returned in input order.
    + slow, fast : double
    +     magnitude check bounds (default 1e-2, 1e4).
    + ecMaxGap : double
    +     how many times the EC median a value must exceed, while sitting
    +     exactly at the EC max, to flag as ec-maximum (default 3.0).
    + repeatMin : double
    +     how many distinct reactions must share one kcat value to flag as
    +     repeated-value (default 5).
    + include : cell
    +     names from {'standard-fallback','tied-isozymes'} to report as well
    +     (default: neither -- both are deliberate choices, not mistakes, so
    +     stay quiet unless asked for).
    + coverage : double
    +     truncate the report to the rows carrying this share of the
    +     *flagged* leverage (default: no truncation).
    + top : double
    +     truncate the report to this many rows (default: no truncation).
    +
    + Returns
    + -------
    + findings : table
    +     one row per free parameter: rxnId, name, ecCode, source, kcat,
    +     leverage, nIsozymes, otherReactions, checks (comma-joined string),
    +     detail. Write to TSV with e.g.
    +         writetable(findings,'findings.tsv','FileType','text','Delimiter','\t')
    +
    + See also
    + --------
    + ecStatsFromBrenda, isozymeTieMap, screenKcatLeverage
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function findings = reviewKcatAssignment(rxnIds,kcats,sources,ecCodes,varargin)
    +0002 % reviewKcatAssignment  Flag kcat assignments that deserve a second look.
    +0003 %
    +0004 % A tuner's largest corrections are rarely discoveries about biology.
    +0005 % They are places the assignment went wrong: a value derived from one
    +0006 % specific-activity measurement, a database maximum standing in for a
    +0007 % distribution with a two-hundred-fold spread, one fallback number reused
    +0008 % across a whole family of reactions. Finding those directly is cheaper
    +0009 % than inferring them from a fit, and a corrected prior propagates to
    +0010 % every model built from the same databases, where a tuned kcat stays in
    +0011 % the model it was tuned on.
    +0012 %
    +0013 % Two design choices, both from measurement rather than taste (see
    +0014 % geckopy's gather_kcats/review.py, which this ports):
    +0015 %
    +0016 % Rank by leverage, and cut the report there. Tightening the checks
    +0017 % themselves does not shorten a report nearly as well, because looking
    +0018 % odd and mattering are unrelated properties. Filtering by leverage keeps
    +0019 % the list short and keeps the entries worth a curator's time.
    +0020 %
    +0021 % Report a parameter once. Isozyme copies the assignment could not
    +0022 % separate share a value and a source, so they share a finding; listing
    +0023 % them separately fills the report with duplicates of one decision.
    +0024 %
    +0025 % Parameters
    +0026 % ----------
    +0027 % rxnIds, kcats, sources, ecCodes : cell/double
    +0028 %     ec.rxns, ec.kcat, ec.source, ec.eccodes (or the equivalent
    +0029 %     subset), all the same length.
    +0030 %
    +0031 % Name-Value Arguments
    +0032 % --------------------
    +0033 % ecStats : containers.Map
    +0034 %     EC code -> struct(nKcat,kcatMax,kcatMedian,values,nSa), as returned
    +0035 %     by ecStatsFromBrenda. Checks needing it are skipped when it is
    +0036 %     absent, so this still runs without a database.
    +0037 % enzymes : cell
    +0038 %     protein ids per kcat (cell of cell arrays), used to count how many
    +0039 %     other reactions share an enzyme.
    +0040 % names : cell
    +0041 %     reaction names, same length as rxnIds (default: not shown).
    +0042 % leverage : double
    +0043 %     per-kcat effect on the distance from a one-at-a-time screen (e.g.
    +0044 %     screenKcatLeverage's leverage column, expanded back to
    +0045 %     ecModel.ec.rxns positions). Without it findings cannot be ranked
    +0046 %     and are returned in input order.
    +0047 % slow, fast : double
    +0048 %     magnitude check bounds (default 1e-2, 1e4).
    +0049 % ecMaxGap : double
    +0050 %     how many times the EC median a value must exceed, while sitting
    +0051 %     exactly at the EC max, to flag as ec-maximum (default 3.0).
    +0052 % repeatMin : double
    +0053 %     how many distinct reactions must share one kcat value to flag as
    +0054 %     repeated-value (default 5).
    +0055 % include : cell
    +0056 %     names from {'standard-fallback','tied-isozymes'} to report as well
    +0057 %     (default: neither -- both are deliberate choices, not mistakes, so
    +0058 %     stay quiet unless asked for).
    +0059 % coverage : double
    +0060 %     truncate the report to the rows carrying this share of the
    +0061 %     *flagged* leverage (default: no truncation).
    +0062 % top : double
    +0063 %     truncate the report to this many rows (default: no truncation).
    +0064 %
    +0065 % Returns
    +0066 % -------
    +0067 % findings : table
    +0068 %     one row per free parameter: rxnId, name, ecCode, source, kcat,
    +0069 %     leverage, nIsozymes, otherReactions, checks (comma-joined string),
    +0070 %     detail. Write to TSV with e.g.
    +0071 %         writetable(findings,'findings.tsv','FileType','text','Delimiter','\t')
    +0072 %
    +0073 % See also
    +0074 % --------
    +0075 % ecStatsFromBrenda, isozymeTieMap, screenKcatLeverage
    +0076 p = parseGECKOargs(varargin, { ...
    +0077     'ecStats', containers.Map('KeyType','char','ValueType','any'); ...
    +0078     'enzymes', {}; ...
    +0079     'names', {}; ...
    +0080     'leverage', []; ...
    +0081     'slow', 1e-2; ...
    +0082     'fast', 1e4; ...
    +0083     'ecMaxGap', 3.0; ...
    +0084     'repeatMin', 5; ...
    +0085     'include', {}; ...
    +0086     'coverage', []; ...
    +0087     'top', []});
    +0088 ecStats   = p.ecStats;
    +0089 enzymes   = p.enzymes;
    +0090 names     = p.names;
    +0091 leverage  = p.leverage;
    +0092 slow      = p.slow;
    +0093 fast      = p.fast;
    +0094 ecMaxGap  = p.ecMaxGap;
    +0095 repeatMin = p.repeatMin;
    +0096 include   = p.include;
    +0097 coverage  = p.coverage;
    +0098 top       = p.top;
    +0099 
    +0100 kcats = kcats(:);
    +0101 n = numel(kcats);
    +0102 if numel(rxnIds) ~= n || numel(sources) ~= n || numel(ecCodes) ~= n
    +0103     error('rxnIds, sources and ecCodes must all have %d entries, matching kcats.', n)
    +0104 end
    +0105 if isempty(leverage)
    +0106     lev = zeros(n,1);
    +0107 else
    +0108     lev = leverage(:);
    +0109 end
    +0110 
    +0111 tie = isozymeTieMap(rxnIds,kcats,'sources',sources);
    +0112 reps = unique(tie);
    +0113 memberLists = cell(numel(reps),1);
    +0114 for r = 1:numel(reps)
    +0115     memberLists{r} = find(tie == reps(r));
    +0116 end
    +0117 
    +0118 % A value reused across many distinct reactions is a fallback wearing a
    +0119 % measurement's label, whatever its source says.
    +0120 reuseMap = containers.Map('KeyType','char','ValueType','any');
    +0121 for i = 1:n
    +0122     key = reuseKey(kcats(i));
    +0123     base = baseReactionLocal(rxnIds{i});
    +0124     if isKey(reuseMap,key)
    +0125         reuseMap(key) = union(reuseMap(key), {base});
    +0126     else
    +0127         reuseMap(key) = {base};
    +0128     end
    +0129 end
    +0130 
    +0131 enzymeRxns = containers.Map('KeyType','char','ValueType','any');
    +0132 if ~isempty(enzymes)
    +0133     for i = 1:n
    +0134         for e = 1:numel(enzymes{i})
    +0135             prot = char(enzymes{i}{e});
    +0136             base = baseReactionLocal(rxnIds{i});
    +0137             if isKey(enzymeRxns,prot)
    +0138                 enzymeRxns(prot) = union(enzymeRxns(prot), {base});
    +0139             else
    +0140                 enzymeRxns(prot) = {base};
    +0141             end
    +0142         end
    +0143     end
    +0144 end
    +0145 
    +0146 rxnIdOut=[]; nameOut=[]; ecOut=[]; sourceOut=[]; kcatOut=[]; leverageOut=[];
    +0147 nIsoOut=[]; otherOut=[]; checksOut=[]; detailOut=[];
    +0148 
    +0149 for r = 1:numel(reps)
    +0150     idx = memberLists{r};
    +0151     i = idx(1);
    +0152     ec = firstEc(ecCodes{i});
    +0153     st = [];
    +0154     if isKey(ecStats,ec)
    +0155         st = ecStats(ec);
    +0156     end
    +0157     checks = {}; detail = {};
    +0158 
    +0159     if ~isempty(st) && st.nKcat == 0
    +0160         checks{end+1} = 'no-ec-evidence'; %#ok<AGROW>
    +0161         if st.nSa > 0
    +0162             detail{end+1} = sprintf('no kcat rows for EC %s; %d specific-activity rows instead', ec, st.nSa); %#ok<AGROW>
    +0163         else
    +0164             detail{end+1} = sprintf('no kcat rows for EC %s', ec); %#ok<AGROW>
    +0165         end
    +0166     end
    +0167     key = reuseKey(kcats(i));
    +0168     if isKey(reuseMap,key) && numel(reuseMap(key)) >= repeatMin
    +0169         checks{end+1} = 'repeated-value'; %#ok<AGROW>
    +0170         detail{end+1} = sprintf('%g 1/s reused across %d reactions', kcats(i), numel(reuseMap(key))); %#ok<AGROW>
    +0171     end
    +0172     if ~isempty(st) && st.nKcat > 0 && isfinite(st.kcatMedian) && st.kcatMedian > 0 ...
    +0173             && abs(kcats(i)-st.kcatMax) <= 1e-9*max(kcats(i),1) && st.kcatMax/st.kcatMedian > ecMaxGap
    +0174         checks{end+1} = 'ec-maximum'; %#ok<AGROW>
    +0175         detail{end+1} = sprintf('took the EC maximum, %.0fx its median over %d rows', st.kcatMax/st.kcatMedian, st.nKcat); %#ok<AGROW>
    +0176     end
    +0177     if kcats(i) < slow || kcats(i) > fast
    +0178         checks{end+1} = 'magnitude'; %#ok<AGROW>
    +0179         detail{end+1} = sprintf('%g 1/s is outside %g-%g', kcats(i), slow, fast); %#ok<AGROW>
    +0180     end
    +0181     if strcmpi(sources{i},'custom') && ~isempty(st) && ismember(round(kcats(i),6), st.values)
    +0182         checks{end+1} = 'custom-duplicate'; %#ok<AGROW>
    +0183         detail{end+1} = 'custom value equals a database value for its own EC'; %#ok<AGROW>
    +0184     end
    +0185     if numel(idx) > 1
    +0186         if ismember('tied-isozymes',include)
    +0187             checks{end+1} = 'tied-isozymes'; %#ok<AGROW>
    +0188         end
    +0189         detail{end+1} = sprintf('%d isozyme copies share this value', numel(idx)); %#ok<AGROW>
    +0190     end
    +0191     if strcmpi(sources{i},'standard')
    +0192         if ~ismember('standard-fallback',include)
    +0193             continue
    +0194         end
    +0195         checks{end+1} = 'standard-fallback'; %#ok<AGROW>
    +0196         detail{end+1} = 'the model''s fallback value, not a measurement'; %#ok<AGROW>
    +0197     end
    +0198 
    +0199     if isempty(checks)
    +0200         continue
    +0201     end
    +0202     others = {};
    +0203     if ~isempty(enzymes)
    +0204         for e = 1:numel(enzymes{i})
    +0205             prot = char(enzymes{i}{e});
    +0206             if isKey(enzymeRxns,prot)
    +0207                 others = union(others, enzymeRxns(prot));
    +0208             end
    +0209         end
    +0210     end
    +0211     others = setdiff(others, {baseReactionLocal(rxnIds{i})});
    +0212 
    +0213     rxnIdOut{end+1,1}   = rxnIds{i}; %#ok<AGROW>
    +0214     if isempty(names)
    +0215         nameOut{end+1,1} = ''; %#ok<AGROW>
    +0216     else
    +0217         nameOut{end+1,1} = names{i}; %#ok<AGROW>
    +0218     end
    +0219     ecOut{end+1,1}       = ec; %#ok<AGROW>
    +0220     sourceOut{end+1,1}   = sources{i}; %#ok<AGROW>
    +0221     kcatOut(end+1,1)     = kcats(i); %#ok<AGROW>
    +0222     leverageOut(end+1,1) = max(lev(idx)); %#ok<AGROW>
    +0223     nIsoOut(end+1,1)     = numel(idx); %#ok<AGROW>
    +0224     otherOut(end+1,1)    = numel(others); %#ok<AGROW>
    +0225     checksOut{end+1,1}   = strjoin(checks,','); %#ok<AGROW>
    +0226     detailOut{end+1,1}   = strjoin(detail,'; '); %#ok<AGROW>
    +0227 end
    +0228 
    +0229 if isempty(rxnIdOut)
    +0230     findings = table(cell(0,1),cell(0,1),cell(0,1),cell(0,1),zeros(0,1),zeros(0,1), ...
    +0231         zeros(0,1),zeros(0,1),cell(0,1),cell(0,1), 'VariableNames', ...
    +0232         {'rxnId','name','ecCode','source','kcat','leverage','nIsozymes','otherReactions','checks','detail'});
    +0233     return
    +0234 end
    +0235 
    +0236 findings = table(rxnIdOut,nameOut,ecOut,sourceOut,kcatOut,leverageOut,nIsoOut,otherOut,checksOut,detailOut, ...
    +0237     'VariableNames',{'rxnId','name','ecCode','source','kcat','leverage','nIsozymes','otherReactions','checks','detail'});
    +0238 findings = sortrows(findings,'leverage','descend');
    +0239 
    +0240 flaggedTotal = sum(findings.leverage);
    +0241 if ~isempty(coverage) && flaggedTotal > 0
    +0242     acc = cumsum(findings.leverage);
    +0243     keepN = find(acc/flaggedTotal >= coverage, 1, 'first');
    +0244     if isempty(keepN)
    +0245         keepN = height(findings);
    +0246     end
    +0247     findings = findings(1:keepN,:);
    +0248 end
    +0249 if ~isempty(top)
    +0250     findings = findings(1:min(top,height(findings)),:);
    +0251 end
    +0252 end
    +0253 
    +0254 function key = reuseKey(kcat)
    +0255 if kcat > 0
    +0256     key = sprintf('%.9f', round(log(kcat),9));
    +0257 else
    +0258     key = 'NONE';
    +0259 end
    +0260 end
    +0261 
    +0262 function ec = firstEc(ecCode)
    +0263 parts = strsplit(char(ecCode), ';');
    +0264 ec = strtrim(parts{1});
    +0265 end
    +0266 
    +0267 function base = baseReactionLocal(rxnId)
    +0268 % Same one-line split as isozymeTieMap's local baseReaction. Kept as a
    +0269 % local duplicate rather than exported from isozymeTieMap.m, since
    +0270 % MATLAB only exposes a file's first function to other files and this is
    +0271 % its only caller here.
    +0272 parts = strsplit(rxnId, '_EXP_');
    +0273 base = parts{1};
    +0274 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/runDLKcat.html b/doc/src/gather_kcats/runDLKcat.html new file mode 100644 index 00000000..6dc6366e --- /dev/null +++ b/doc/src/gather_kcats/runDLKcat.html @@ -0,0 +1,145 @@ + + + + Description of runDLKcat + + + + + + + + + +
    Home > src > gather_kcats > runDLKcat.m
    + + + +

    runDLKcat +

    + +

    PURPOSE ^

    +
    runDLKcat Run DLKcat to predict kcat values from a Docker image.
    + +

    SYNOPSIS ^

    +
    function runDLKcat(varargin)
    + +

    DESCRIPTION ^

    +
     runDLKcat  Run DLKcat to predict kcat values from a Docker image.
    +
    + Runs DLKcat via a Docker image; once it completes successfully, the
    + DLKcat file is overwritten with the predicted output, in the model-
    + specific 'data' sub-folder taken from modelAdapter (e.g.
    + GECKO/tutorials/tutorial_yeast-GEM/data/DLKcat.tsv).
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + filePath : char
    +     path to the DLKcat.tsv file (default: data/DLKcat.tsv).
    +
    + Notes
    + -----
    + 1. Requires Docker to be installed, and Docker Desktop running. Visit
    +    "https://www.docker.com".
    + 2. Runtime will depend on whether the image is to be downloaded or not.
    +
    + See also
    + --------
    + writeDLKcatInput, readDLKcatOutput
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • kcatsFromDLKcat kcatsFromDLKcat Gather kcats from DLKcat and keep them as a source file.
    + + + + +

    SOURCE CODE ^

    +
    0001 function runDLKcat(varargin)
    +0002 % runDLKcat  Run DLKcat to predict kcat values from a Docker image.
    +0003 %
    +0004 % Runs DLKcat via a Docker image; once it completes successfully, the
    +0005 % DLKcat file is overwritten with the predicted output, in the model-
    +0006 % specific 'data' sub-folder taken from modelAdapter (e.g.
    +0007 % GECKO/tutorials/tutorial_yeast-GEM/data/DLKcat.tsv).
    +0008 %
    +0009 % Name-Value Arguments
    +0010 % --------------------
    +0011 % modelAdapter : ModelAdapter
    +0012 %     a loaded model adapter (default: the current default model adapter).
    +0013 % filePath : char
    +0014 %     path to the DLKcat.tsv file (default: data/DLKcat.tsv).
    +0015 %
    +0016 % Notes
    +0017 % -----
    +0018 % 1. Requires Docker to be installed, and Docker Desktop running. Visit
    +0019 %    "https://www.docker.com".
    +0020 % 2. Runtime will depend on whether the image is to be downloaded or not.
    +0021 %
    +0022 % See also
    +0023 % --------
    +0024 % writeDLKcatInput, readDLKcatOutput
    +0025 
    +0026 p = parseGECKOargs(varargin, { ...
    +0027     'modelAdapter', []; ...
    +0028     'filePath',     []});
    +0029 modelAdapter = p.modelAdapter;
    +0030 filePath     = p.filePath;
    +0031 
    +0032 if isempty(modelAdapter)
    +0033     modelAdapter = ModelAdapterManager.getDefault();
    +0034     if isempty(modelAdapter)
    +0035         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0036     end
    +0037 end
    +0038 params = modelAdapter.params;
    +0039 % Make sure path is full, not relative
    +0040 [~, params.path] = fileattrib(params.path);
    +0041 params.path=params.path.Name;
    +0042 
    +0043 if isempty(filePath)
    +0044     filePath = fullfile(params.path,'data','DLKcat.tsv');
    +0045 elseif strcmp(filePath(end),{'\','/'})
    +0046     filePath = fullfile(filePath,'DLKcat.tsv');
    +0047 end
    +0048 filePath = checkFileExistence(filePath,1);
    +0049 
    +0050 copyfile(filePath, fullfile(params.path,'data','tempDLKcat.tsv'));
    +0051     
    +0052 
    +0053 %% Check and install requirements
    +0054 % On macOS, Docker might not be properly loaded if MATLAB is started via
    +0055 % launcher and not terminal.
    +0056 if ismac
    +0057     setenv('PATH', strcat('/usr/local/bin', ':', getenv("PATH")));
    +0058 end
    +0059 
    +0060 % Check if Docker is installed
    +0061 [checks.docker.status, checks.docker.out] = system('docker --version');
    +0062 if checks.docker.status ~= 0
    +0063     error('Cannot find Docker, make sure it is installed. If it is, it might be required to start Matlab from the command-line instead of the launcher in order for Docker to be detected and used.')
    +0064 end
    +0065 
    +0066 disp('Running DLKcat prediction, this may take many minutes, especially the first time.')
    +0067 status = system(['docker run --rm -v "' fullfile(params.path,'/data') '":/data ghcr.io/sysbiochalmers/dlkcat-gecko:0.1 /bin/bash -c "python DLKcat.py /data/tempDLKcat.tsv /data/tempDLKcatOutput.tsv"']);
    +0068 delete(fullfile(params.path,'/data/tempDLKcat.tsv'));
    +0069 
    +0070 if status == 0 && exist(fullfile(params.path,'data/tempDLKcatOutput.tsv'))
    +0071     movefile(fullfile(params.path,'/data/tempDLKcatOutput.tsv'), filePath);
    +0072     disp('DKLcat prediction completed.');
    +0073 else    
    +0074     error('DLKcat encountered an error or it did not create any output file.')
    +0075 end
    +0076
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/saveKcatSource.html b/doc/src/gather_kcats/saveKcatSource.html new file mode 100644 index 00000000..97493742 --- /dev/null +++ b/doc/src/gather_kcats/saveKcatSource.html @@ -0,0 +1,498 @@ + + + + Description of saveKcatSource + + + + + + + + + +
    Home > src > gather_kcats > saveKcatSource.m
    + + + +

    saveKcatSource +

    + +

    PURPOSE ^

    +
    saveKcatSource Write a kcatList to a kcat source file of the project.
    + +

    SYNOPSIS ^

    +
    function filename = saveKcatSource(model, kcatList, name, varargin)
    + +

    DESCRIPTION ^

    +
     saveKcatSource  Write a kcatList to a kcat source file of the project.
    +
    + Writes the kcat values of kcatList to data/kcats/<name>.tsv in the
    + project folder, the file that loadKcatSource reads back. Rows are keyed
    + by their conventional reaction and enzyme set (see getEcRxnKeys), not
    + by model.ec.rxns, so the file stays valid when the ecModel is rebuilt.
    + kcatsFromBrenda, kcatsFromDLKcat and kcatsFromOKP write these files for
    + their sources; use this function for a kcatList made in another way.
    +
    + The file is UTF-8 text. It starts with '#' header lines (source,
    + generator, parameters, data, kind, created), then a tab-separated table
    + with the columns rxn, enzymes, substrate, kcat, log10_sd, source,
    + detail, ec_code and note, sorted by all columns from rxn onwards.
    + Left out are:
    + - rows whose kcat is not a positive finite number (0 means no value
    +   was found);
    + - rows of model.ec reactions without enzymes, which have no enzyme
    +   constraint and could not be told apart from their isozymes.
    +
    + Parameters
    + ----------
    + model : struct
    +     the ecModel the kcatList refers to.
    + kcatList : struct
    +     kcat values as returned by kcatsFromBrenda, fuzzyKcatMatching,
    +     readDLKcatOutput, readOpenKineticsPredictorOutput or mergeKcats:
    +     fields rxns and kcats, optionally source, substrates, eccodes,
    +     wildcardLvl, origin, kcatSource, log10sd and detail (further
    +     key=value pairs for the detail column).
    + name : char
    +     name of the source; the file is <name>.tsv.
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + folder : char
    +     folder to write to (default: data/kcats in the project folder).
    + generator : char
    +     what produced the values (default: 'saveKcatSource').
    + parameters : struct
    +     settings used to produce the values, written as compact JSON with
    +     sorted keys (default: none).
    + data : char
    +     version of the data the values come from, e.g. a BRENDA release
    +     (default: empty).
    + kind : char
    +     'gathered' (default) or 'curated'.
    +
    + A file whose header says 'kind: curated' or 'source: custom', or named
    + custom.tsv, is never written.
    +
    + Returns
    + -------
    + filename : char
    +     the file written.
    +
    + Examples
    + --------
    +     kcatList = fuzzyKcatMatching(ecModel);
    +     saveKcatSource(ecModel, kcatList, 'mybrenda');
    +
    + See also
    + --------
    + kcatsFromBrenda, loadKcatSource, getEcRxnKeys
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • getEcRxnKeys getEcRxnKeys Build-independent keys of the model.ec reactions.
    +This function is called by: +
      +
    • kcatsFromBrenda kcatsFromBrenda Gather kcats from BRENDA and keep them as a source file.
    • kcatsFromDLKcat kcatsFromDLKcat Gather kcats from DLKcat and keep them as a source file.
    • kcatsFromECTree kcatsFromECTree Estimate kcats from the EC tree and keep them as a source file.
    • kcatsFromHomologs kcatsFromHomologs Estimate kcats from measured homologs and keep them as a source file.
    • kcatsFromOKP kcatsFromOKP Gather kcats from OpenKineticsPredictor and keep them as a source file.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function filename = saveKcatSource(model, kcatList, name, varargin)
    +0002 % saveKcatSource  Write a kcatList to a kcat source file of the project.
    +0003 %
    +0004 % Writes the kcat values of kcatList to data/kcats/<name>.tsv in the
    +0005 % project folder, the file that loadKcatSource reads back. Rows are keyed
    +0006 % by their conventional reaction and enzyme set (see getEcRxnKeys), not
    +0007 % by model.ec.rxns, so the file stays valid when the ecModel is rebuilt.
    +0008 % kcatsFromBrenda, kcatsFromDLKcat and kcatsFromOKP write these files for
    +0009 % their sources; use this function for a kcatList made in another way.
    +0010 %
    +0011 % The file is UTF-8 text. It starts with '#' header lines (source,
    +0012 % generator, parameters, data, kind, created), then a tab-separated table
    +0013 % with the columns rxn, enzymes, substrate, kcat, log10_sd, source,
    +0014 % detail, ec_code and note, sorted by all columns from rxn onwards.
    +0015 % Left out are:
    +0016 % - rows whose kcat is not a positive finite number (0 means no value
    +0017 %   was found);
    +0018 % - rows of model.ec reactions without enzymes, which have no enzyme
    +0019 %   constraint and could not be told apart from their isozymes.
    +0020 %
    +0021 % Parameters
    +0022 % ----------
    +0023 % model : struct
    +0024 %     the ecModel the kcatList refers to.
    +0025 % kcatList : struct
    +0026 %     kcat values as returned by kcatsFromBrenda, fuzzyKcatMatching,
    +0027 %     readDLKcatOutput, readOpenKineticsPredictorOutput or mergeKcats:
    +0028 %     fields rxns and kcats, optionally source, substrates, eccodes,
    +0029 %     wildcardLvl, origin, kcatSource, log10sd and detail (further
    +0030 %     key=value pairs for the detail column).
    +0031 % name : char
    +0032 %     name of the source; the file is <name>.tsv.
    +0033 %
    +0034 % Name-Value Arguments
    +0035 % --------------------
    +0036 % modelAdapter : ModelAdapter
    +0037 %     a loaded model adapter (default: the current default model adapter).
    +0038 % folder : char
    +0039 %     folder to write to (default: data/kcats in the project folder).
    +0040 % generator : char
    +0041 %     what produced the values (default: 'saveKcatSource').
    +0042 % parameters : struct
    +0043 %     settings used to produce the values, written as compact JSON with
    +0044 %     sorted keys (default: none).
    +0045 % data : char
    +0046 %     version of the data the values come from, e.g. a BRENDA release
    +0047 %     (default: empty).
    +0048 % kind : char
    +0049 %     'gathered' (default) or 'curated'.
    +0050 %
    +0051 % A file whose header says 'kind: curated' or 'source: custom', or named
    +0052 % custom.tsv, is never written.
    +0053 %
    +0054 % Returns
    +0055 % -------
    +0056 % filename : char
    +0057 %     the file written.
    +0058 %
    +0059 % Examples
    +0060 % --------
    +0061 %     kcatList = fuzzyKcatMatching(ecModel);
    +0062 %     saveKcatSource(ecModel, kcatList, 'mybrenda');
    +0063 %
    +0064 % See also
    +0065 % --------
    +0066 % kcatsFromBrenda, loadKcatSource, getEcRxnKeys
    +0067 
    +0068 names = {'modelAdapter','folder','generator','parameters','data','kind'};
    +0069 checkOptions(varargin, names, 'saveKcatSource');
    +0070 p = parseGECKOargs(varargin, { ...
    +0071     'modelAdapter', []; ...
    +0072     'folder',       []; ...
    +0073     'generator',    'saveKcatSource'; ...
    +0074     'parameters',   struct(); ...
    +0075     'data',         ''; ...
    +0076     'kind',         'gathered'});
    +0077 kind = validatestring(p.kind, {'gathered','curated'});
    +0078 name = char(name);
    +0079 filename = kcatSourceFile(name, p.folder, p.modelAdapter);
    +0080 
    +0081 [baseRxns, enzymeSets] = getEcRxnKeys(model);
    +0082 [found, idx] = ismember(kcatList.rxns(:), model.ec.rxns);
    +0083 if ~all(found)
    +0084     error('saveKcatSource:unknownRxns', '%s', ravenList( ...
    +0085         'These kcatList reactions are not in model.ec.rxns:', kcatList.rxns(~found), false));
    +0086 end
    +0087 
    +0088 n = numel(kcatList.rxns);
    +0089 kcats = double(kcatList.kcats(:));
    +0090 if numel(kcats) ~= n
    +0091     error('saveKcatSource:fields', 'kcatList.kcats and kcatList.rxns differ in length.')
    +0092 end
    +0093 substrate = textColumn(kcatList, 'substrates', n);
    +0094 ecCode    = textColumn(kcatList, 'eccodes', n);
    +0095 extra     = textColumn(kcatList, 'detail', n);
    +0096 if isfield(kcatList, 'kcatSource')
    +0097     source = textColumn(kcatList, 'kcatSource', n);
    +0098 elseif isfield(kcatList, 'source')
    +0099     source = repmat({char(kcatList.source)}, n, 1);
    +0100 else
    +0101     source = repmat({name}, n, 1);
    +0102 end
    +0103 wc     = numColumn(kcatList, 'wildcardLvl', n);
    +0104 origin = numColumn(kcatList, 'origin', n);
    +0105 sd     = numColumn(kcatList, 'log10sd', n);
    +0106 
    +0107 keep = kcats > 0 & isfinite(kcats);
    +0108 noEnzymes = keep & cellfun(@isempty, enzymeSets(idx));
    +0109 if any(noEnzymes)
    +0110     fprintf('%d kcats of reactions without enzymes are not written to %s.\n', sum(noEnzymes), filename);
    +0111 end
    +0112 keep = find(keep & ~noEnzymes);
    +0113 
    +0114 clean = @(c) regexprep(string(c(:)), '[\t\r\n]', ' ');
    +0115 rows = strings(numel(keep), 9);
    +0116 if ~isempty(keep)
    +0117     wcText = strings(numel(keep), 1);
    +0118     hasWc = ~isnan(wc(keep));
    +0119     wcText(hasWc) = "wc=" + string(fix(wc(keep(hasWc))));
    +0120     originText = strings(numel(keep), 1);
    +0121     hasOrigin = ~isnan(origin(keep));
    +0122     originText(hasOrigin) = "origin=" + string(fix(origin(keep(hasOrigin))));
    +0123     detail = join([wcText, originText, strtrim(clean(extra(keep)))], "; ", 2);
    +0124     detail = regexprep(detail, '^(; )+|(; )+$', '');
    +0125     detail = regexprep(detail, '(; ){2,}', '; ');
    +0126     rows(:, 1) = clean(baseRxns(idx(keep)));
    +0127     rows(:, 2) = clean(enzymeSets(idx(keep)));
    +0128     rows(:, 3) = clean(substrate(keep));
    +0129     rows(:, 4) = formatNumbers(kcats(keep));
    +0130     rows(:, 5) = formatNumbers(sd(keep));
    +0131     rows(:, 6) = clean(source(keep));
    +0132     rows(:, 7) = detail;
    +0133     rows(:, 8) = clean(ecCode(keep));
    +0134     % Sorted by the columns in this order, as geckopy sorts tuples: one key
    +0135     % per row, the fields joined by a character below any in the text.
    +0136     [~, order] = sort(join(rows(:, [1 2 3 6 4 5 7 8 9]), char(1), 2));
    +0137     rows = rows(order, :);
    +0138 end
    +0139 
    +0140 folder = fileparts(filename);
    +0141 if ~isfolder(folder)
    +0142     mkdir(folder);
    +0143 end
    +0144 fid = fopen(filename, 'w', 'n', 'UTF-8');
    +0145 if fid < 0
    +0146     error('saveKcatSource:write', 'Cannot write %s', filename)
    +0147 end
    +0148 cleanup = onCleanup(@() fclose(fid));
    +0149 fprintf(fid, '# source: %s\n', name);
    +0150 fprintf(fid, '# generator: %s (GECKO %s)\n', cleanText(p.generator), geckoVersion());
    +0151 fprintf(fid, '# parameters: %s\n', kcatSourceJson(p.parameters));
    +0152 fprintf(fid, '# data: %s\n', cleanText(p.data));
    +0153 fprintf(fid, '# kind: %s\n', kind);
    +0154 fprintf(fid, '# created: %s\n', char(datetime('now', 'TimeZone', 'UTC', 'Format', 'yyyy-MM-dd''T''HH:mm:ss''Z''')));
    +0155 fprintf(fid, 'rxn\tenzymes\tsubstrate\tkcat\tlog10_sd\tsource\tdetail\tec_code\tnote\n');
    +0156 if ~isempty(rows)
    +0157     fprintf(fid, '%s\n', join(rows, sprintf('\t'), 2));
    +0158 end
    +0159 end
    +0160 
    +0161 function col = textColumn(s, field, n)
    +0162 % A kcatList field as an n x 1 cell of char; a cell of several entries
    +0163 % (e.g. all substrates of a reaction) is joined by '; '.
    +0164 col = repmat({''}, n, 1);
    +0165 if ~isfield(s, field) || isempty(s.(field))
    +0166     return
    +0167 end
    +0168 v = s.(field);
    +0169 if ischar(v) || isstring(v)
    +0170     v = cellstr(v);
    +0171 end
    +0172 if numel(v) ~= n
    +0173     error('saveKcatSource:fields', 'kcatList.%s and kcatList.rxns differ in length.', field)
    +0174 end
    +0175 for i = 1:n
    +0176     e = v{i};
    +0177     if iscell(e)
    +0178         e = strjoin(cellfun(@char, e(:)', 'UniformOutput', false), '; ');
    +0179     elseif isstring(e)
    +0180         e = char(e);
    +0181     elseif ~ischar(e)
    +0182         e = '';
    +0183     end
    +0184     col{i} = e;
    +0185 end
    +0186 end
    +0187 
    +0188 function col = numColumn(s, field, n)
    +0189 col = nan(n, 1);
    +0190 if isfield(s, field) && ~isempty(s.(field))
    +0191     if numel(s.(field)) ~= n
    +0192         error('saveKcatSource:fields', 'kcatList.%s and kcatList.rxns differ in length.', field)
    +0193     end
    +0194     col = double(s.(field)(:));
    +0195 end
    +0196 end
    +0197 
    +0198 function t = formatNumbers(x)
    +0199 % formatKcatNumber for a vector, in a few vectorized passes.
    +0200 x = x(:);
    +0201 t = strings(numel(x), 1);
    +0202 whole = isfinite(x) & x == round(x) & abs(x) < 1e15;
    +0203 t(whole) = compose('%d', x(whole));
    +0204 t(isinf(x) & x > 0) = "Inf";
    +0205 t(isinf(x) & x < 0) = "-Inf";
    +0206 open = find(isfinite(x) & ~whole);
    +0207 for digits = 1:17
    +0208     if isempty(open)
    +0209         break
    +0210     end
    +0211     candidate = compose(sprintf('%%.%dg', digits), x(open));
    +0212     hit = str2double(candidate) == x(open);
    +0213     t(open(hit)) = candidate(hit);
    +0214     open = open(~hit);
    +0215 end
    +0216 end
    +0217 
    +0218 function t = cleanText(t)
    +0219 t = regexprep(char(t), '[\t\r\n]', ' ');
    +0220 end
    +0221 
    +0222 function v = geckoVersion()
    +0223 v = '';
    +0224 file = fullfile(findGECKOroot, 'version.txt');
    +0225 if isfile(file)
    +0226     v = strtrim(fileread(file));
    +0227 end
    +0228 end
    +0229 
    +0230 function filename = kcatSourceFile(name, folder, modelAdapter)
    +0231 name = char(name);
    +0232 if isempty(regexp(name, '^[A-Za-z0-9_.-]+$', 'once'))
    +0233     error('saveKcatSource:invalidName', ...
    +0234         'The source name "%s" may only contain letters, digits, ''_'', ''-'' and ''.''.', name)
    +0235 end
    +0236 if isempty(folder)
    +0237     if isempty(modelAdapter)
    +0238         modelAdapter = ModelAdapterManager.getDefault();
    +0239         if isempty(modelAdapter)
    +0240             error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0241         end
    +0242     end
    +0243     folder = fullfile(modelAdapter.params.path, 'data', 'kcats');
    +0244 end
    +0245 filename = fullfile(char(folder), [name '.tsv']);
    +0246 if strcmpi(name, 'custom')
    +0247     error('saveKcatSource:curated', ['custom.tsv holds curated kcats and is not ' ...
    +0248         'written by GECKO; edit it by hand.'])
    +0249 end
    +0250 if isfile(filename)
    +0251     meta = readHeaderLines(filename);
    +0252     if (isfield(meta, 'kind') && strcmpi(meta.kind, 'curated')) || ...
    +0253             (isfield(meta, 'source') && strcmpi(meta.source, 'custom'))
    +0254         error('saveKcatSource:curated', '%s is curated by hand and is not overwritten.', filename)
    +0255     end
    +0256 end
    +0257 end
    +0258 
    +0259 function meta = readHeaderLines(filename)
    +0260 % Only the header lines at the top, so that a damaged table does not stop
    +0261 % a gathered file from being written again.
    +0262 meta = struct();
    +0263 fid = fopen(filename, 'r', 'n', 'UTF-8');
    +0264 if fid < 0
    +0265     return
    +0266 end
    +0267 cleanup = onCleanup(@() fclose(fid));
    +0268 line = fgetl(fid);
    +0269 if ischar(line)
    +0270     line = regexprep(line, ['^' char(65279)], '');
    +0271 end
    +0272 while ischar(line) && (isempty(strtrim(line)) || startsWith(unquoteField(line), '#'))
    +0273     [key, value] = parseHeaderLine(line);
    +0274     if ~isempty(key)
    +0275         meta.(key) = value;
    +0276     end
    +0277     line = fgetl(fid);
    +0278 end
    +0279 end
    +0280 
    +0281 function j = kcatSourceJson(v)
    +0282 if isstruct(v) && isscalar(v)
    +0283     f = sort(fieldnames(v));
    +0284     parts = cell(1, numel(f));
    +0285     for k = 1:numel(f)
    +0286         parts{k} = [jsonString(f{k}) ':' kcatSourceJson(v.(f{k}))];
    +0287     end
    +0288     j = ['{' strjoin(parts, ',') '}'];
    +0289 elseif ischar(v) || (isstring(v) && isscalar(v))
    +0290     j = jsonString(char(v));
    +0291 elseif iscell(v)
    +0292     j = ['[' strjoin(cellfun(@kcatSourceJson, v(:)', 'UniformOutput', false), ',') ']'];
    +0293 elseif (isnumeric(v) || islogical(v)) && numel(v) ~= 1
    +0294     j = ['[' strjoin(arrayfun(@kcatSourceJson, v(:)', 'UniformOutput', false), ',') ']'];
    +0295 elseif islogical(v)
    +0296     j = 'false';
    +0297     if v
    +0298         j = 'true';
    +0299     end
    +0300 elseif isnumeric(v)
    +0301     if ~isfinite(v)
    +0302         j = 'null';
    +0303     else
    +0304         j = formatKcatNumber(double(v));
    +0305     end
    +0306 elseif isempty(v)
    +0307     j = 'null';
    +0308 else
    +0309     error('kcatSourceJson:type', 'Parameters of class %s cannot be written.', class(v))
    +0310 end
    +0311 end
    +0312 
    +0313 function s = jsonString(s)
    +0314 % JSON escapes, as Python's json.dumps(ensure_ascii=False).
    +0315 out = '';
    +0316 for c = s
    +0317     switch c
    +0318         case '"', out = [out '\"']; %#ok<AGROW>
    +0319         case '\', out = [out '\\']; %#ok<AGROW>
    +0320         case char(8), out = [out '\b']; %#ok<AGROW>
    +0321         case char(9), out = [out '\t']; %#ok<AGROW>
    +0322         case char(10), out = [out '\n']; %#ok<AGROW>
    +0323         case char(12), out = [out '\f']; %#ok<AGROW>
    +0324         case char(13), out = [out '\r']; %#ok<AGROW>
    +0325         otherwise
    +0326             if double(c) < 32
    +0327                 out = [out sprintf('\\u%04x', double(c))]; %#ok<AGROW>
    +0328             else
    +0329                 out = [out c]; %#ok<AGROW>
    +0330             end
    +0331     end
    +0332 end
    +0333 s = ['"' out '"'];
    +0334 end
    +0335 
    +0336 function t = formatKcatNumber(x)
    +0337 if isnan(x)
    +0338     t = '';
    +0339 elseif isinf(x)
    +0340     t = 'Inf';
    +0341     if x < 0
    +0342         t = '-Inf';
    +0343     end
    +0344 elseif x == round(x) && abs(x) < 1e15
    +0345     t = sprintf('%d', x);
    +0346 else
    +0347     for digits = 1:17
    +0348         t = sprintf('%.*g', digits, x);
    +0349         if str2double(t) == x
    +0350             break
    +0351         end
    +0352     end
    +0353 end
    +0354 end
    +0355 
    +0356 function [key, value] = parseHeaderLine(line)
    +0357 key = ''; value = '';
    +0358 tok = regexp(unquoteField(line), '^\s*#\s*([A-Za-z][A-Za-z0-9_]{0,62})\s*:\s?(.*)$', 'tokens', 'once');
    +0359 if ~isempty(tok)
    +0360     key = lower(tok{1});
    +0361     value = strtrim(tok{2});
    +0362 end
    +0363 end
    +0364 
    +0365 function t = unquoteField(t)
    +0366 t = strtrim(t);
    +0367 if numel(t) >= 2 && t(1) == '"' && t(end) == '"'
    +0368     t = strtrim(strrep(t(2:end-1), '""', '"'));
    +0369 end
    +0370 end
    +0371 
    +0372 function checkOptions(args, names, functionName)
    +0373 % Options are name-value pairs with known names, so a misspelled option is
    +0374 % an error instead of being taken as a positional argument.
    +0375 id = [functionName ':arguments'];
    +0376 given = args(1:2:end);
    +0377 if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given))
    +0378     error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', '))
    +0379 end
    +0380 unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names);
    +0381 if ~isempty(unknown)
    +0382     error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ...
    +0383         strjoin(names, ', '))
    +0384 end
    +0385 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/submitOpenKineticsPredictor.html b/doc/src/gather_kcats/submitOpenKineticsPredictor.html new file mode 100644 index 00000000..5ab11f0d --- /dev/null +++ b/doc/src/gather_kcats/submitOpenKineticsPredictor.html @@ -0,0 +1,292 @@ + + + + Description of submitOpenKineticsPredictor + + + + + + + + + +
    Home > src > gather_kcats > submitOpenKineticsPredictor.m
    + + + +

    submitOpenKineticsPredictor +

    + +

    PURPOSE ^

    +
    submitOpenKineticsPredictor Submit a kcat prediction job to OpenKineticsPredictor.
    + +

    SYNOPSIS ^

    +
    function jobId = submitOpenKineticsPredictor(model, varargin)
    + +

    DESCRIPTION ^

    +
     submitOpenKineticsPredictor  Submit a kcat prediction job to OpenKineticsPredictor.
    +
    + Builds the OpenKineticsPredictor input (protein sequences + single-substrate
    + SMILES, via writeOpenKineticsPredictorInput) and submits a kcat prediction
    + job to the OKP REST API (https://predictor.openkinetics.org/). The returned
    + job id is also stored in data/OKP_job.txt, so fetchOpenKineticsPredictor can
    + pick it up later.
    +
    + Predictors available via OKP: CataPro, CatPred, CatRange, DLKcat, EITLEM,
    + KinForm-H, KinForm-L, OmniESI, OmniESI-O2DENet, TurNup, UniKP (see GET
    + /api/v1/methods/). CatRange predicts a class of kcat values;
    + readOpenKineticsPredictorOutput uses its geometric midpoint.
    +
    + Obtaining an API key:
    +   The OKP API requires a personal Bearer key (looks like 'ak_...'). Keys
    +   are free and need no registration:
    +     1. Open https://predictor.openkinetics.org/api-docs in a browser.
    +     2. In the "API key generator" section, click "Generate".
    +     3. Copy the key shown (it is displayed only once). If you lose it,
    +        revoke it on the same page and generate a new one.
    +   Keys are tied to your IP and carry a daily prediction quota that resets
    +   at midnight UTC.
    +
    +   The key is a secret; do NOT put it in the model adapter (which is
    +   shared/committed). Provide it in one of three ways, checked in this
    +   order: the apiKey argument below; the OKP_API_KEY environment variable
    +   (setenv('OKP_API_KEY',...)); or a plain-text file data/okpApiKey.txt in
    +   the model's data folder (this name is git-ignored by GECKO).
    +
    + Parameters
    + ----------
    + model : struct
    +     ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + ecRxns : logical
    +     logical vector indicating which reactions to include (default: all
    +     reactions).
    + overwrite : logical
    +     rebuild data/OKP.csv even if it exists (default false; an existing
    +     file is reused).
    + apiKey : char
    +     OKP API key (default: resolved from OKP_API_KEY or data/okpApiKey.txt,
    +     see above).
    + method : char
    +     predictor to use (default: params.okp.method, or 'CataPro').
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + jobId : char
    +     the OKP job identifier (also written to data/OKP_job.txt).
    +
    + Examples
    + --------
    +     jobId = submitOpenKineticsPredictor(model);
    +     jobId = submitOpenKineticsPredictor(model, 'overwrite', true, 'apiKey', 'ak_...', 'method', 'DLKcat');
    +
    + See also
    + --------
    + fetchOpenKineticsPredictor, writeOpenKineticsPredictorInput
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: + +This function is called by: +
      +
    • kcatsFromOKP kcatsFromOKP Gather kcats from OpenKineticsPredictor and keep them as a source file.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function jobId = submitOpenKineticsPredictor(model, varargin)
    +0002 % submitOpenKineticsPredictor  Submit a kcat prediction job to OpenKineticsPredictor.
    +0003 %
    +0004 % Builds the OpenKineticsPredictor input (protein sequences + single-substrate
    +0005 % SMILES, via writeOpenKineticsPredictorInput) and submits a kcat prediction
    +0006 % job to the OKP REST API (https://predictor.openkinetics.org/). The returned
    +0007 % job id is also stored in data/OKP_job.txt, so fetchOpenKineticsPredictor can
    +0008 % pick it up later.
    +0009 %
    +0010 % Predictors available via OKP: CataPro, CatPred, CatRange, DLKcat, EITLEM,
    +0011 % KinForm-H, KinForm-L, OmniESI, OmniESI-O2DENet, TurNup, UniKP (see GET
    +0012 % /api/v1/methods/). CatRange predicts a class of kcat values;
    +0013 % readOpenKineticsPredictorOutput uses its geometric midpoint.
    +0014 %
    +0015 % Obtaining an API key:
    +0016 %   The OKP API requires a personal Bearer key (looks like 'ak_...'). Keys
    +0017 %   are free and need no registration:
    +0018 %     1. Open https://predictor.openkinetics.org/api-docs in a browser.
    +0019 %     2. In the "API key generator" section, click "Generate".
    +0020 %     3. Copy the key shown (it is displayed only once). If you lose it,
    +0021 %        revoke it on the same page and generate a new one.
    +0022 %   Keys are tied to your IP and carry a daily prediction quota that resets
    +0023 %   at midnight UTC.
    +0024 %
    +0025 %   The key is a secret; do NOT put it in the model adapter (which is
    +0026 %   shared/committed). Provide it in one of three ways, checked in this
    +0027 %   order: the apiKey argument below; the OKP_API_KEY environment variable
    +0028 %   (setenv('OKP_API_KEY',...)); or a plain-text file data/okpApiKey.txt in
    +0029 %   the model's data folder (this name is git-ignored by GECKO).
    +0030 %
    +0031 % Parameters
    +0032 % ----------
    +0033 % model : struct
    +0034 %     ecModel in GECKO 3 format (with ecModel.ec structure).
    +0035 %
    +0036 % Name-Value Arguments
    +0037 % --------------------
    +0038 % ecRxns : logical
    +0039 %     logical vector indicating which reactions to include (default: all
    +0040 %     reactions).
    +0041 % overwrite : logical
    +0042 %     rebuild data/OKP.csv even if it exists (default false; an existing
    +0043 %     file is reused).
    +0044 % apiKey : char
    +0045 %     OKP API key (default: resolved from OKP_API_KEY or data/okpApiKey.txt,
    +0046 %     see above).
    +0047 % method : char
    +0048 %     predictor to use (default: params.okp.method, or 'CataPro').
    +0049 % modelAdapter : ModelAdapter
    +0050 %     a loaded model adapter (default: the current default model adapter).
    +0051 %
    +0052 % Returns
    +0053 % -------
    +0054 % jobId : char
    +0055 %     the OKP job identifier (also written to data/OKP_job.txt).
    +0056 %
    +0057 % Examples
    +0058 % --------
    +0059 %     jobId = submitOpenKineticsPredictor(model);
    +0060 %     jobId = submitOpenKineticsPredictor(model, 'overwrite', true, 'apiKey', 'ak_...', 'method', 'DLKcat');
    +0061 %
    +0062 % See also
    +0063 % --------
    +0064 % fetchOpenKineticsPredictor, writeOpenKineticsPredictorInput
    +0065 
    +0066 p = parseGECKOargs(varargin, { ...
    +0067     'ecRxns',       []; ...
    +0068     'overwrite',    []; ...
    +0069     'apiKey',       []; ...
    +0070     'method',       []; ...
    +0071     'modelAdapter', []});
    +0072 ecRxns       = p.ecRxns;
    +0073 overwrite    = p.overwrite;
    +0074 apiKey       = p.apiKey;
    +0075 method       = p.method;
    +0076 modelAdapter = p.modelAdapter;
    +0077 
    +0078 if isempty(modelAdapter)
    +0079     modelAdapter = ModelAdapterManager.getDefault();
    +0080     if isempty(modelAdapter)
    +0081         error('Either provide a modelAdapter or set the default in ModelAdapterManager.')
    +0082     end
    +0083 end
    +0084 params = modelAdapter.params;
    +0085 
    +0086 if isempty(overwrite)
    +0087     overwrite = false;
    +0088 end
    +0089 if isempty(ecRxns)
    +0090     ecRxns = true(numel(model.ec.rxns),1);
    +0091 elseif ~islogical(ecRxns) || numel(ecRxns) ~= numel(model.ec.rxns)
    +0092     error('ecRxns should be a logical vector with length equal to model.ec.rxns')
    +0093 end
    +0094 
    +0095 apiKey = resolveOkpApiKey(apiKey, params.path);
    +0096 
    +0097 % Resolve predictor method and request options: defaults -> params.okp.* ->
    +0098 % the method argument (highest priority, applied last).
    +0099 okp = struct('method','CataPro', ...
    +0100              'handleLongSequences','truncate', ...
    +0101              'includeSimilarityColumns',true,'canonicalizeSubstrates',true);
    +0102 if isfield(params,'okp')
    +0103     fn = fieldnames(params.okp);
    +0104     for i=1:numel(fn); okp.(fn{i}) = params.okp.(fn{i}); end
    +0105 end
    +0106 if ~isempty(method)
    +0107     okp.method = method;
    +0108 end
    +0109 
    +0110 %% Build (or reuse) the input CSV --- the same function, writing the same
    +0111 % file, as the file-based workflow (writeOpenKineticsPredictorInput /
    +0112 % readOpenKineticsPredictorOutput), rather than a separate reimplementation.
    +0113 filename = fullfile(params.path,'data','OKP.csv');
    +0114 if exist(filename,'file') && ~overwrite
    +0115     fprintf('Using existing %s (set overwrite=true to rebuild).\n', filename);
    +0116 else
    +0117     writeOpenKineticsPredictorInput(model, 'ecRxns', ecRxns, 'modelAdapter', modelAdapter, ...
    +0118         'onlyWithSmiles', true, 'overwrite', true);
    +0119 end
    +0120 
    +0121 %% Submit via the OKP REST API
    +0122 % GECKO only ever predicts kcat.
    +0123 url = 'https://predictor.openkinetics.org/api/v1/submit/';
    +0124 
    +0125 targetsJson = '["kcat"]';
    +0126 methodsJson = ['{"kcat":"' okp.method '"}'];
    +0127 
    +0128 import matlab.net.http.*
    +0129 import matlab.net.http.io.*
    +0130 provider = MultipartFormProvider( ...
    +0131     'file',                     FileProvider(filename), ...
    +0132     'targets',                  targetsJson, ...
    +0133     'methods',                  methodsJson, ...
    +0134     'handleLongSequences',      okp.handleLongSequences, ...
    +0135     'includeSimilarityColumns', boolToStr(okp.includeSimilarityColumns), ...
    +0136     'canonicalizeSubstrates',   boolToStr(okp.canonicalizeSubstrates));
    +0137 header = matlab.net.http.HeaderField('Authorization', ['Bearer ' apiKey]);
    +0138 req    = RequestMessage('POST', header, provider);
    +0139 resp   = req.send(url);
    +0140 
    +0141 data = resp.Body.Data;
    +0142 if resp.StatusCode ~= matlab.net.http.StatusCode.OK && ...
    +0143         resp.StatusCode ~= matlab.net.http.StatusCode.Created
    +0144     error('OKP submit failed (HTTP %d): %s', double(resp.StatusCode), okpErrorText(data));
    +0145 end
    +0146 if ~isstruct(data) || ~isfield(data,'jobId')
    +0147     error('OKP submit returned an unexpected response (no jobId).');
    +0148 end
    +0149 jobId = data.jobId;
    +0150 
    +0151 %% Persist job metadata (plain text, one field per line)
    +0152 metaFile = fullfile(params.path,'data','OKP_job.txt');
    +0153 fID = fopen(metaFile,'w');
    +0154 fprintf(fID,'jobId: %s\n', jobId);
    +0155 fprintf(fID,'method: %s\n', okp.method);
    +0156 fprintf(fID,'submittedAt: %s\n', char(datetime('now','TimeZone','UTC','Format','yyyy-MM-dd''T''HH:mm:ss''Z''')));
    +0157 fclose(fID);
    +0158 
    +0159 fprintf('Submitted OKP job %s (method: %s). Metadata stored at %s\n', jobId, okp.method, metaFile);
    +0160 fprintf('Check progress later with fetchOpenKineticsPredictor, or at https://predictor.openkinetics.org/\n');
    +0161 end
    +0162 
    +0163 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0164 function s = boolToStr(b)
    +0165 if islogical(b) || isnumeric(b)
    +0166     if b; s = 'true'; else; s = 'false'; end
    +0167 else
    +0168     s = char(b);
    +0169 end
    +0170 end
    +0171 
    +0172 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0173 function txt = okpErrorText(data)
    +0174 if isstruct(data) && isfield(data,'error')
    +0175     txt = data.error;
    +0176 elseif ischar(data) || isstring(data)
    +0177     txt = char(data);
    +0178 else
    +0179     txt = 'unknown error';
    +0180 end
    +0181 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/updateKcatSources.html b/doc/src/gather_kcats/updateKcatSources.html new file mode 100644 index 00000000..71e8a6fc --- /dev/null +++ b/doc/src/gather_kcats/updateKcatSources.html @@ -0,0 +1,373 @@ + + + + Description of updateKcatSources + + + + + + + + + +
    Home > src > gather_kcats > updateKcatSources.m
    + + + +

    updateKcatSources +

    + +

    PURPOSE ^

    +
    updateKcatSources Gather the kcat sources that the configuration needs.
    + +

    SYNOPSIS ^

    +
    function report = updateKcatSources(model, varargin)
    + +

    DESCRIPTION ^

    +
     updateKcatSources  Gather the kcat sources that the configuration needs.
    +
    + Lists the kcat source files that [kcat_assignment] in model_adapter.toml
    + uses (see collectKcats), and gathers those that are missing or outdated
    + with kcatsFromBrenda, kcatsFromECTree, kcatsFromDLKcat and kcatsFromOKP:
    +
    + - a file is outdated when its header records other settings than
    +   [kcat_sources.<name>] asks for (presets set these for brenda and
    +   ec_tree), or, for brenda and ec_tree, another BRENDA release than the
    +   BRENDA files in use;
    + - brenda and ec_tree are made again; dlkcat reads data/DLKcat.tsv if it exists and
    +   runs DLKcat (Docker) otherwise; okp_<method> submits or fetches a job,
    +   and reports it as pending while the job runs;
    + - custom.tsv and other files it cannot gather are left as they are.
    +
    + Requirements are checked first: Docker for a DLKcat run and an
    + OpenKineticsPredictor API key for OKP. Calling it again is safe: files
    + that are current are not gathered again.
    +
    + Per-source settings are read from model_adapter.toml, for instance:
    +
    +     [kcat_sources.brenda]
    +     aggregation = "median"
    +
    +     [kcat_sources.okp_catapro]
    +     method = "CataPro"
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + dryRun : logical
    +     only report what would be gathered (default false).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + report : table
    +     one row per source: source, status (current, gathered, pending,
    +     outdated, missing, failed or skipped) and note.
    +
    + Examples
    + --------
    +     updateKcatSources(ecModel, 'dryRun', true)
    +     updateKcatSources(ecModel);
    +
    + See also
    + --------
    + collectKcats, assignKcats, kcatsFromBrenda, kcatsFromDLKcat, kcatsFromOKP
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • kcatAssignmentConfig kcatAssignmentConfig The kcat assignment settings of a model adapter.
    • kcatsFromBrenda kcatsFromBrenda Gather kcats from BRENDA and keep them as a source file.
    • kcatsFromDLKcat kcatsFromDLKcat Gather kcats from DLKcat and keep them as a source file.
    • kcatsFromECTree kcatsFromECTree Estimate kcats from the EC tree and keep them as a source file.
    • kcatsFromHomologs kcatsFromHomologs Estimate kcats from measured homologs and keep them as a source file.
    • kcatsFromOKP kcatsFromOKP Gather kcats from OpenKineticsPredictor and keep them as a source file.
    • resolveOkpApiKey resolveOkpApiKey Resolve the OpenKineticsPredictor API key.
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function report = updateKcatSources(model, varargin)
    +0002 % updateKcatSources  Gather the kcat sources that the configuration needs.
    +0003 %
    +0004 % Lists the kcat source files that [kcat_assignment] in model_adapter.toml
    +0005 % uses (see collectKcats), and gathers those that are missing or outdated
    +0006 % with kcatsFromBrenda, kcatsFromECTree, kcatsFromDLKcat and kcatsFromOKP:
    +0007 %
    +0008 % - a file is outdated when its header records other settings than
    +0009 %   [kcat_sources.<name>] asks for (presets set these for brenda and
    +0010 %   ec_tree), or, for brenda and ec_tree, another BRENDA release than the
    +0011 %   BRENDA files in use;
    +0012 % - brenda and ec_tree are made again; dlkcat reads data/DLKcat.tsv if it exists and
    +0013 %   runs DLKcat (Docker) otherwise; okp_<method> submits or fetches a job,
    +0014 %   and reports it as pending while the job runs;
    +0015 % - custom.tsv and other files it cannot gather are left as they are.
    +0016 %
    +0017 % Requirements are checked first: Docker for a DLKcat run and an
    +0018 % OpenKineticsPredictor API key for OKP. Calling it again is safe: files
    +0019 % that are current are not gathered again.
    +0020 %
    +0021 % Per-source settings are read from model_adapter.toml, for instance:
    +0022 %
    +0023 %     [kcat_sources.brenda]
    +0024 %     aggregation = "median"
    +0025 %
    +0026 %     [kcat_sources.okp_catapro]
    +0027 %     method = "CataPro"
    +0028 %
    +0029 % Parameters
    +0030 % ----------
    +0031 % model : struct
    +0032 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0033 %
    +0034 % Name-Value Arguments
    +0035 % --------------------
    +0036 % dryRun : logical
    +0037 %     only report what would be gathered (default false).
    +0038 % modelAdapter : ModelAdapter
    +0039 %     a loaded model adapter (default: the current default model adapter).
    +0040 %
    +0041 % Returns
    +0042 % -------
    +0043 % report : table
    +0044 %     one row per source: source, status (current, gathered, pending,
    +0045 %     outdated, missing, failed or skipped) and note.
    +0046 %
    +0047 % Examples
    +0048 % --------
    +0049 %     updateKcatSources(ecModel, 'dryRun', true)
    +0050 %     updateKcatSources(ecModel);
    +0051 %
    +0052 % See also
    +0053 % --------
    +0054 % collectKcats, assignKcats, kcatsFromBrenda, kcatsFromDLKcat, kcatsFromOKP
    +0055 
    +0056 checkOptions(varargin, {'dryRun','modelAdapter'}, 'updateKcatSources');
    +0057 p = parseGECKOargs(varargin, {'dryRun', false; 'modelAdapter', []});
    +0058 modelAdapter = p.modelAdapter;
    +0059 if isempty(modelAdapter)
    +0060     modelAdapter = ModelAdapterManager.getDefault();
    +0061     if isempty(modelAdapter)
    +0062         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0063     end
    +0064 end
    +0065 params = modelAdapter.params;
    +0066 config = kcatAssignmentConfig(params);
    +0067 kcatDir = fullfile(params.path, 'data', 'kcats');
    +0068 
    +0069 names = {};
    +0070 for s = 1:numel(config.stages)
    +0071     for t = 1:numel(config.stages(s).files)
    +0072         token = config.stages(s).files{t};
    +0073         if startsWith(token, 'database_')
    +0074             token = 'brenda';
    +0075         end
    +0076         if ~any(strcmp(names, token))
    +0077             names{end+1} = token; %#ok<AGROW>
    +0078         end
    +0079     end
    +0080 end
    +0081 
    +0082 status = cell(numel(names), 1);
    +0083 note = cell(numel(names), 1);
    +0084 for k = 1:numel(names)
    +0085     name = names{k};
    +0086     file = fullfile(kcatDir, [name '.tsv']);
    +0087     wanted = struct();
    +0088     if isfield(config.sources, name)
    +0089         wanted = config.sources.(name);
    +0090     end
    +0091     [status{k}, note{k}] = check(name, file, wanted);
    +0092     if any(strcmp(status{k}, {'missing','outdated'})) && ~p.dryRun
    +0093         [status{k}, note{k}] = gather(model, name, wanted, modelAdapter);
    +0094     end
    +0095 end
    +0096 report = table(names(:), status, note, 'VariableNames', {'source','status','note'});
    +0097 disp(report)
    +0098 
    +0099     function [st, nt] = check(name, file, wanted)
    +0100         st = 'current'; nt = '';
    +0101         if strcmp(name, 'custom')
    +0102             st = 'skipped'; nt = 'curated by hand';
    +0103             return
    +0104         elseif ~any(strcmp(name, {'brenda','ec_tree','homologs','dlkcat'})) && ~startsWith(name, 'okp_')
    +0105             st = 'skipped'; nt = 'not a source GECKO gathers';
    +0106             return
    +0107         end
    +0108         if ~isfile(file)
    +0109             st = 'missing';
    +0110             return
    +0111         end
    +0112         meta = readHeaderLines(file);
    +0113         recorded = struct();
    +0114         if isfield(meta, 'parameters') && ~isempty(meta.parameters)
    +0115             recorded = jsondecode(meta.parameters);
    +0116         end
    +0117         f = fieldnames(wanted);
    +0118         for i = 1:numel(f)
    +0119             if ~isfield(recorded, f{i}) || ~isequal(normalizeValue(recorded.(f{i})), normalizeValue(wanted.(f{i})))
    +0120                 st = 'outdated';
    +0121                 nt = sprintf('%s differs from model_adapter.toml', f{i});
    +0122                 return
    +0123             end
    +0124         end
    +0125         if any(strcmp(name, {'brenda','ec_tree','homologs'}))
    +0126             release = brendaRelease(modelAdapter, name);
    +0127             if isfield(meta, 'data') && ~isempty(release) && ~strcmp(meta.data, release)
    +0128                 st = 'outdated';
    +0129                 nt = sprintf('made from %s; GECKO has %s', meta.data, release);
    +0130             end
    +0131         end
    +0132     end
    +0133 end
    +0134 
    +0135 function [st, nt] = gather(model, name, wanted, modelAdapter)
    +0136 st = 'gathered'; nt = '';
    +0137 try
    +0138     if strcmp(name, 'brenda')
    +0139         args = {};
    +0140         if isfield(wanted, 'aggregation'), args = [args, {'aggregation', wanted.aggregation}]; end
    +0141         if isfield(wanted, 'force_wildcard_level'), args = [args, {'forceWClvl', wanted.force_wildcard_level}]; end
    +0142         kcatsFromBrenda(model, args{:}, 'modelAdapter', modelAdapter);
    +0143     elseif strcmp(name, 'ec_tree')
    +0144         args = {};
    +0145         if isfield(wanted, 'k'), args = {'k', double(wanted.k)}; end
    +0146         kcatsFromECTree(model, args{:}, 'modelAdapter', modelAdapter);
    +0147     elseif strcmp(name, 'homologs')
    +0148         args = {};
    +0149         if isfield(wanted, 'k'), args = [args, {'k', double(wanted.k)}]; end
    +0150         if isfield(wanted, 'min_identity'), args = [args, {'minIdentity', double(wanted.min_identity)}]; end
    +0151         if isfield(wanted, 'coverage'), args = [args, {'coverage', double(wanted.coverage)}]; end
    +0152         kcatsFromHomologs(model, args{:}, 'modelAdapter', modelAdapter);
    +0153     elseif strcmp(name, 'dlkcat')
    +0154         run = ~isfile(fullfile(modelAdapter.params.path, 'data', 'DLKcat.tsv'));
    +0155         if run
    +0156             [status, ~] = system('docker --version');
    +0157             if status ~= 0
    +0158                 st = 'failed'; nt = 'DLKcat needs Docker to run';
    +0159                 return
    +0160             end
    +0161         end
    +0162         kcatsFromDLKcat(model, 'run', run, 'modelAdapter', modelAdapter);
    +0163     else % okp_<method>
    +0164         method = okpMethod(name, wanted);
    +0165         resolveOkpApiKey('', modelAdapter.params.path); % errors without a key
    +0166         [~, done] = kcatsFromOKP(model, 'method', method, 'saveAs', name, 'modelAdapter', modelAdapter);
    +0167         if ~done
    +0168             st = 'pending'; nt = sprintf('OKP job for %s still running; call again later', method);
    +0169         end
    +0170     end
    +0171 catch err
    +0172     st = 'failed'; nt = err.message;
    +0173 end
    +0174 end
    +0175 
    +0176 function method = okpMethod(name, wanted)
    +0177 % The OKP method of okp_<method>: from [kcat_sources.okp_<method>] method,
    +0178 % or the known method whose name gives this file name.
    +0179 if isfield(wanted, 'method')
    +0180     method = char(wanted.method);
    +0181     return
    +0182 end
    +0183 known = {'CataPro','CatPred','CatRange','DLKcat','EITLEM','KinForm-H','KinForm-L', ...
    +0184     'OmniESI','OmniESI-O2DENet','TurNup','UniKP'};
    +0185 tags = cellfun(@(m) ['okp_' lower(regexprep(m, '[^A-Za-z0-9]+', '_'))], known, 'UniformOutput', false);
    +0186 hit = strcmp(tags, name);
    +0187 if ~any(hit)
    +0188     error('updateKcatSources:okpMethod', ['Set the OKP method of %s in model_adapter.toml: ' ...
    +0189         '[kcat_sources.%s] method = "..."'], name, name)
    +0190 end
    +0191 method = known{hit};
    +0192 end
    +0193 
    +0194 function v = normalizeValue(v)
    +0195 if isstring(v)
    +0196     v = char(v);
    +0197 end
    +0198 if ischar(v)
    +0199     v = lower(v);
    +0200 elseif islogical(v)
    +0201     v = double(v);
    +0202 end
    +0203 end
    +0204 
    +0205 function release = brendaRelease(modelAdapter, name)
    +0206 % The release line of the BRENDA file a source is made from.
    +0207 release = '';
    +0208 files = struct('brenda', 'kcat.tsv', 'ec_tree', 'measurements.tsv', 'homologs', 'measurements.tsv');
    +0209 fid = fopen(fullfile(modelAdapter.getBrendaDBFolder(), files.(name)), 'r');
    +0210 if fid < 0
    +0211     return
    +0212 end
    +0213 line = fgetl(fid);
    +0214 fclose(fid);
    +0215 tok = regexp(line, '^#\s*(BRENDA release [^ ]+)', 'tokens', 'once');
    +0216 if ~isempty(tok)
    +0217     release = tok{1};
    +0218 end
    +0219 end
    +0220 
    +0221 function meta = readHeaderLines(filename)
    +0222 % Only the header lines at the top, so that a damaged table does not stop
    +0223 % a gathered file from being written again.
    +0224 meta = struct();
    +0225 fid = fopen(filename, 'r', 'n', 'UTF-8');
    +0226 if fid < 0
    +0227     return
    +0228 end
    +0229 cleanup = onCleanup(@() fclose(fid));
    +0230 line = fgetl(fid);
    +0231 if ischar(line)
    +0232     line = regexprep(line, ['^' char(65279)], '');
    +0233 end
    +0234 while ischar(line) && (isempty(strtrim(line)) || startsWith(unquoteField(line), '#'))
    +0235     [key, value] = parseHeaderLine(line);
    +0236     if ~isempty(key)
    +0237         meta.(key) = value;
    +0238     end
    +0239     line = fgetl(fid);
    +0240 end
    +0241 end
    +0242 
    +0243 function [key, value] = parseHeaderLine(line)
    +0244 key = ''; value = '';
    +0245 tok = regexp(unquoteField(line), '^\s*#\s*([A-Za-z][A-Za-z0-9_]{0,62})\s*:\s?(.*)$', 'tokens', 'once');
    +0246 if ~isempty(tok)
    +0247     key = lower(tok{1});
    +0248     value = strtrim(tok{2});
    +0249 end
    +0250 end
    +0251 
    +0252 function t = unquoteField(t)
    +0253 t = strtrim(t);
    +0254 if numel(t) >= 2 && t(1) == '"' && t(end) == '"'
    +0255     t = strtrim(strrep(t(2:end-1), '""', '"'));
    +0256 end
    +0257 end
    +0258 
    +0259 function checkOptions(args, names, functionName)
    +0260 % Options are name-value pairs with known names, so a misspelled option is
    +0261 % an error instead of being taken as a positional argument.
    +0262 id = [functionName ':arguments'];
    +0263 given = args(1:2:end);
    +0264 if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given))
    +0265     error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', '))
    +0266 end
    +0267 unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names);
    +0268 if ~isempty(unknown)
    +0269     error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ...
    +0270         strjoin(names, ', '))
    +0271 end
    +0272 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/writeDLKcatInput.html b/doc/src/gather_kcats/writeDLKcatInput.html new file mode 100644 index 00000000..412eb399 --- /dev/null +++ b/doc/src/gather_kcats/writeDLKcatInput.html @@ -0,0 +1,207 @@ + + + + Description of writeDLKcatInput + + + + + + + + + +
    Home > src > gather_kcats > writeDLKcatInput.m
    + + + +

    writeDLKcatInput +

    + +

    PURPOSE ^

    +
    writeDLKcatInput Prepare and write the input file for DLKcat.
    + +

    SYNOPSIS ^

    +
    function writtenTable = writeDLKcatInput(model, varargin)
    + +

    DESCRIPTION ^

    +
     writeDLKcatInput  Prepare and write the input file for DLKcat.
    +
    + Prepares the input for DLKcat, and writes it to data/DLKcat.tsv in the
    + obj.params.path specified in the ModelAdapter.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + ecRxns : logical
    +     for which reactions (from model.ec.rxns) DLKcat should predict kcat
    +     values, provided as logical vector with same length as model.ec.rxns
    +     (default: all reactions).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + onlyWithSmiles : logical
    +     whether to only include metabolites with SMILES (default true).
    + filename : char
    +     path to the input file, including the filename and .tsv extension
    +     (default: data/DLKcat.tsv from the obj.params.path folder specified in
    +     the modelAdapter).
    + overwrite : logical
    +     whether existing file should be overwritten (default false, to prevent
    +     overwriting a file that already contains DLKcat-predicted kcat values).
    +
    + Returns
    + -------
    + writtenTable : cell
    +     the table written, mainly to be used for testing purposes.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     writtenTable = writeDLKcatInput(model);
    +     writtenTable = writeDLKcatInput(model, 'onlyWithSmiles', false);
    +
    + See also
    + --------
    + runDLKcat, readDLKcatOutput, extractEnzymeSubstratePairs
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: + +This function is called by: +
      +
    • kcatsFromDLKcat kcatsFromDLKcat Gather kcats from DLKcat and keep them as a source file.
    + + + + +

    SOURCE CODE ^

    +
    0001 function writtenTable = writeDLKcatInput(model, varargin)
    +0002 % writeDLKcatInput  Prepare and write the input file for DLKcat.
    +0003 %
    +0004 % Prepares the input for DLKcat, and writes it to data/DLKcat.tsv in the
    +0005 % obj.params.path specified in the ModelAdapter.
    +0006 %
    +0007 % Parameters
    +0008 % ----------
    +0009 % model : struct
    +0010 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0011 %
    +0012 % Name-Value Arguments
    +0013 % --------------------
    +0014 % ecRxns : logical
    +0015 %     for which reactions (from model.ec.rxns) DLKcat should predict kcat
    +0016 %     values, provided as logical vector with same length as model.ec.rxns
    +0017 %     (default: all reactions).
    +0018 % modelAdapter : ModelAdapter
    +0019 %     a loaded model adapter (default: the current default model adapter).
    +0020 % onlyWithSmiles : logical
    +0021 %     whether to only include metabolites with SMILES (default true).
    +0022 % filename : char
    +0023 %     path to the input file, including the filename and .tsv extension
    +0024 %     (default: data/DLKcat.tsv from the obj.params.path folder specified in
    +0025 %     the modelAdapter).
    +0026 % overwrite : logical
    +0027 %     whether existing file should be overwritten (default false, to prevent
    +0028 %     overwriting a file that already contains DLKcat-predicted kcat values).
    +0029 %
    +0030 % Returns
    +0031 % -------
    +0032 % writtenTable : cell
    +0033 %     the table written, mainly to be used for testing purposes.
    +0034 %
    +0035 % Examples
    +0036 % --------
    +0037 %     % optional arguments may be given positionally or as name-value pairs:
    +0038 %     writtenTable = writeDLKcatInput(model);
    +0039 %     writtenTable = writeDLKcatInput(model, 'onlyWithSmiles', false);
    +0040 %
    +0041 % See also
    +0042 % --------
    +0043 % runDLKcat, readDLKcatOutput, extractEnzymeSubstratePairs
    +0044 
    +0045 p = parseGECKOargs(varargin, { ...
    +0046     'ecRxns',         []; ...
    +0047     'modelAdapter',   []; ...
    +0048     'onlyWithSmiles', []; ...
    +0049     'filename',       []; ...
    +0050     'overwrite',      []});
    +0051 ecRxnsSel      = p.ecRxns;
    +0052 modelAdapter   = p.modelAdapter;
    +0053 onlyWithSmiles = p.onlyWithSmiles;
    +0054 filename       = p.filename;
    +0055 overwrite      = p.overwrite;
    +0056 
    +0057 if isempty(ecRxnsSel)
    +0058     ecRxnsSel = true(numel(model.ec.rxns),1);
    +0059 elseif ~logical(ecRxnsSel)
    +0060     error('ecRxns should be provided as logical vector')
    +0061 elseif numel(ecRxnsSel)~=numel(model.ec.rxns)
    +0062     error('Length of ecRxns is not the same as model.ec.rxns')
    +0063 end
    +0064 ecRxnsSel = find(ecRxnsSel); % Change to indices, into the full model.ec.rxns
    +0065 
    +0066 if isempty(modelAdapter)
    +0067     modelAdapter = ModelAdapterManager.getDefault();
    +0068     if isempty(modelAdapter)
    +0069         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0070     end
    +0071 end
    +0072 params = modelAdapter.params;
    +0073 
    +0074 if isempty(onlyWithSmiles)
    +0075     onlyWithSmiles=true;
    +0076 end
    +0077 
    +0078 if isempty(filename)
    +0079     filename = fullfile(params.path,'data','DLKcat.tsv');
    +0080 elseif ~endsWith(filename,'.tsv')
    +0081     error('If filename is provided, it should include the .tsv extension.')
    +0082 end
    +0083 
    +0084 if isempty(overwrite) || ~overwrite % If is true
    +0085     if exist(filename,'file')
    +0086         error([filename ' already exists, either delete it first, or set the overwrite input argument as true'])
    +0087     end
    +0088 end
    +0089 
    +0090 pairs = extractEnzymeSubstratePairs(model, 'ecRxns', ismember((1:numel(model.ec.rxns))', ecRxnsSel), ...
    +0091     'modelAdapter', modelAdapter);
    +0092 
    +0093 % Prepare output
    +0094 out(1,:) = model.ec.rxns(pairs.ecRxn);
    +0095 out(2,:) = model.ec.genes(pairs.protein);
    +0096 out(3,:) = model.metNames(pairs.met);
    +0097 if isfield(model,'metSmiles')
    +0098     out(4,:) = model.metSmiles(pairs.met);
    +0099 else
    +0100     out(4,:) = cell(numel(pairs.met),1);
    +0101 end
    +0102 
    +0103 out(5,:) = model.ec.sequence(pairs.protein);
    +0104 if onlyWithSmiles
    +0105     out(:,cellfun(@isempty,out(4,:))) = [];
    +0106 else
    +0107     out(4,cellfun(@isempty,out(4,:))) = {'None'};
    +0108 end
    +0109 out(6,:) = cell(numel(out(1,:)),1);
    +0110 out(6,:) = {'NA'};
    +0111 
    +0112 % Write file
    +0113 fID = fopen(filename,'w');
    +0114 fprintf(fID,'%s\t%s\t%s\t%s\t%s\t%s\n',out{:});
    +0115 fclose(fID);
    +0116 fprintf('Model-specific DLKcat input stored at %s\n',filename);
    +0117 
    +0118 writtenTable = out;
    +0119 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/gather_kcats/writeOpenKineticsPredictorInput.html b/doc/src/gather_kcats/writeOpenKineticsPredictorInput.html new file mode 100644 index 00000000..4d7b9370 --- /dev/null +++ b/doc/src/gather_kcats/writeOpenKineticsPredictorInput.html @@ -0,0 +1,271 @@ + + + + Description of writeOpenKineticsPredictorInput + + + + + + + + + +
    Home > src > gather_kcats > writeOpenKineticsPredictorInput.m
    + + + +

    writeOpenKineticsPredictorInput +

    + +

    PURPOSE ^

    +
    writeOpenKineticsPredictorInput Write input file for OpenKineticsPredictor.
    + +

    SYNOPSIS ^

    +
    function writeOpenKineticsPredictorInput(model, varargin)
    + +

    DESCRIPTION ^

    +
     writeOpenKineticsPredictorInput  Write input file for OpenKineticsPredictor.
    +
    + Prepares input for OpenKineticsPredictor: protein sequences and single-
    + substrate SMILES, which allows the use of the following predictors: DLKcat;
    + EITLEM; UniKP; KinForm-H; KinForm-L; CataPro; CatPred.
    +
    + The function writes OKP.csv, that can be used as input file at
    + https://predictor.openkinetics.org/
    +
    + The OpenKineticsPredictor output file can be used to generate a kcatList
    + through readOpenKineticsPredictorOutput.
    +
    + Parameters
    + ----------
    + model : struct
    +     ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + ecRxns : logical
    +     logical vector indicating which reactions to include (default: all
    +     reactions).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + onlyWithSmiles : logical
    +     only include entries with SMILES (default true).
    + overwrite : logical
    +     overwrite existing file (default false).
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     writeOpenKineticsPredictorInput(model, ecRxns);
    +     writeOpenKineticsPredictorInput(model, 'onlyWithSmiles', false);
    +
    + See also
    + --------
    + readOpenKineticsPredictorOutput, writeDLKcatInput
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: + + + + + +

    SOURCE CODE ^

    +
    0001 function writeOpenKineticsPredictorInput(model, varargin)
    +0002 % writeOpenKineticsPredictorInput  Write input file for OpenKineticsPredictor.
    +0003 %
    +0004 % Prepares input for OpenKineticsPredictor: protein sequences and single-
    +0005 % substrate SMILES, which allows the use of the following predictors: DLKcat;
    +0006 % EITLEM; UniKP; KinForm-H; KinForm-L; CataPro; CatPred.
    +0007 %
    +0008 % The function writes OKP.csv, that can be used as input file at
    +0009 % https://predictor.openkinetics.org/
    +0010 %
    +0011 % The OpenKineticsPredictor output file can be used to generate a kcatList
    +0012 % through readOpenKineticsPredictorOutput.
    +0013 %
    +0014 % Parameters
    +0015 % ----------
    +0016 % model : struct
    +0017 %     ecModel in GECKO 3 format (with ecModel.ec structure).
    +0018 %
    +0019 % Name-Value Arguments
    +0020 % --------------------
    +0021 % ecRxns : logical
    +0022 %     logical vector indicating which reactions to include (default: all
    +0023 %     reactions).
    +0024 % modelAdapter : ModelAdapter
    +0025 %     a loaded model adapter (default: the current default model adapter).
    +0026 % onlyWithSmiles : logical
    +0027 %     only include entries with SMILES (default true).
    +0028 % overwrite : logical
    +0029 %     overwrite existing file (default false).
    +0030 %
    +0031 % Examples
    +0032 % --------
    +0033 %     % optional arguments may be given positionally or as name-value pairs:
    +0034 %     writeOpenKineticsPredictorInput(model, ecRxns);
    +0035 %     writeOpenKineticsPredictorInput(model, 'onlyWithSmiles', false);
    +0036 %
    +0037 % See also
    +0038 % --------
    +0039 % readOpenKineticsPredictorOutput, writeDLKcatInput
    +0040 
    +0041 [geckoPath, ~] = findGECKOroot();
    +0042 
    +0043 %% Parse inputs
    +0044 p = parseGECKOargs(varargin, { ...
    +0045     'ecRxns',         []; ...
    +0046     'modelAdapter',   []; ...
    +0047     'onlyWithSmiles', []; ...
    +0048     'overwrite',      []});
    +0049 ecRxns         = p.ecRxns;
    +0050 modelAdapter   = p.modelAdapter;
    +0051 onlyWithSmiles = p.onlyWithSmiles;
    +0052 overwrite      = p.overwrite;
    +0053 
    +0054 if isempty(ecRxns)
    +0055     ecRxns = true(numel(model.ec.rxns),1);
    +0056 elseif ~islogical(ecRxns) || numel(ecRxns) ~= numel(model.ec.rxns)
    +0057     error('ecRxns should be a logical vector with length equal to model.ec.rxns')
    +0058 end
    +0059 
    +0060 if isempty(modelAdapter)
    +0061     modelAdapter = ModelAdapterManager.getDefault();
    +0062     if isempty(modelAdapter)
    +0063         error('Either provide a modelAdapter or set the default in ModelAdapterManager.')
    +0064     end
    +0065 end
    +0066 params = modelAdapter.params;
    +0067 
    +0068 if isempty(onlyWithSmiles)
    +0069     onlyWithSmiles = true;
    +0070 end
    +0071 
    +0072 if isempty(overwrite)
    +0073     overwrite = false;
    +0074 end
    +0075 
    +0076 %% Output files
    +0077 filename = fullfile(params.path,'data','OKP.csv');
    +0078 if ~overwrite && exist(filename,'file')
    +0079     error('%s already exists. Set overwrite=true to replace it.', filename)
    +0080 end
    +0081 
    +0082 %% Map ec.rxns to model.rxns
    +0083 if model.ec.geckoLight
    +0084    origRxns = extractAfter(model.ec.rxns, 4);
    +0085 else
    +0086    origRxns = model.ec.rxns;
    +0087 end
    +0088 
    +0089 ecRxnsIdx = find(ecRxns);
    +0090 [found, origRxnIdxs] = ismember(origRxns(ecRxnsIdx), model.rxns);
    +0091 if ~all(found)
    +0092     error('Not all reactions in model.ec.rxns found in model.rxns')
    +0093 end
    +0094 
    +0095 %% Build reduced stoichiometric matrix (ignore certain metabolites)
    +0096 % Load metabolites to ignore (reuses DLKcat files)
    +0097 if exist(fullfile(params.path,'data','DLKcatIgnoreMets.tsv'),'file')
    +0098     ignoreFile = fullfile(params.path,'data','DLKcatIgnoreMets.tsv');
    +0099 else
    +0100     ignoreFile = fullfile(geckoPath,'databases','DLKcatIgnoreMets.tsv');
    +0101 end
    +0102 fID = fopen(ignoreFile);
    +0103 fileData = textscan(fID,'%s %s','delimiter','\t');
    +0104 fclose(fID);
    +0105 [ignoreMets, ignoreSmiles] = deal(fileData{[1,2]});
    +0106 
    +0107 % Normalize metabolite names (remove special characters, lowercase)
    +0108 metsNorm        = lower(regexprep(model.metNames,'[^0-9a-zA-Z]+',''));
    +0109 ignoreMetsNorm  = lower(regexprep(ignoreMets,'[^0-9a-zA-Z]+',''));
    +0110 ignoreSmiles(cellfun(@isempty,ignoreSmiles)) = [];
    +0111 
    +0112 % Mark metabolites to ignore
    +0113 ignoreMetsIdx = ismember(metsNorm, ignoreMetsNorm);
    +0114 if isfield(model,'metSmiles')
    +0115     ignoreMetsIdx = ignoreMetsIdx | ismember(model.metSmiles, ignoreSmiles);
    +0116 end
    +0117 ignoreMetsIdx = ignoreMetsIdx | startsWith(model.mets,'prot_');
    +0118 
    +0119 reducedS = model.S;
    +0120 reducedS(ignoreMetsIdx,:) = 0;
    +0121 
    +0122 %% Remove currency metabolite pairs (reuses DLKcat files)
    +0123 if exist(fullfile(params.path,'data','DLKcatCurrencyMets.tsv'),'file')
    +0124     currencyFile = fullfile(params.path,'data','DLKcatCurrencyMets.tsv');
    +0125 else
    +0126     currencyFile = fullfile(geckoPath,'databases','DLKcatCurrencyMets.tsv');
    +0127 end
    +0128 fID = fopen(currencyFile);
    +0129 fileData = textscan(fID,'%s %s','delimiter','\t');
    +0130 fclose(fID);
    +0131 [currencyMets(:,1), currencyMets(:,2)] = deal(fileData{[1,2]});
    +0132 currencyMets = lower(regexprep(currencyMets,'[^0-9a-zA-Z]+',''));
    +0133 for i=1:size(currencyMets,1)
    +0134     subs = strcmp(currencyMets(i,1),metsNorm);
    +0135     prod = strcmp(currencyMets(i,2),metsNorm);
    +0136     [~,subsRxns]=find(reducedS(subs,:));
    +0137     [~,prodRxns]=find(reducedS(prod,:));
    +0138     pairRxns = intersect(subsRxns,prodRxns);
    +0139     tempRedS=reducedS;
    +0140     tempRedS([find(subs);find(prod)],pairRxns) = 0;
    +0141     % Do not remove currency mets if no substrate remains
    +0142     rxnsWithRemainingSubstrates = any(tempRedS(:,pairRxns) < 0,1);
    +0143     reducedS([find(subs);find(prod)],intersect(pairRxns,pairRxns(rxnsWithRemainingSubstrates))) = 0;
    +0144 end
    +0145 
    +0146 
    +0147 %% Extract substrates for selected reactions only
    +0148 clearedS = reducedS(:, origRxnIdxs);
    +0149 
    +0150 % Find all substrates (negative stoichiometry)
    +0151 [substrateIdxs, reactionIdxs] = find(clearedS < 0);
    +0152 
    +0153 % Find proteins catalyzing each reaction. reactionIdxs indexes clearedS's
    +0154 % columns, i.e. positions within the requested ecRxnsIdx subset -- map back
    +0155 % through ecRxnsIdx to the absolute model.ec.rxnEnzMat row before indexing it.
    +0156 [proteinIdxs, rxnEnzIdxs] = find(model.ec.rxnEnzMat(ecRxnsIdx(reactionIdxs),:)');
    +0157 
    +0158 %% Build output: sequence and SMILES
    +0159 sequences = model.ec.sequence(proteinIdxs);
    +0160 
    +0161 if isfield(model,'metSmiles')
    +0162     smiles = model.metSmiles(substrateIdxs(rxnEnzIdxs));
    +0163 else
    +0164     smiles = cell(size(sequences));
    +0165 end
    +0166 
    +0167 %% Filter empty entries
    +0168 if onlyWithSmiles
    +0169     valid = ~cellfun(@isempty, sequences) & ~cellfun(@isempty, smiles);
    +0170 else
    +0171     valid = ~cellfun(@isempty, sequences);
    +0172     smiles(cellfun(@isempty, smiles)) = {'None'};
    +0173 end
    +0174 
    +0175 sequences = sequences(valid);
    +0176 smiles = smiles(valid);
    +0177 
    +0178 %% Write output file
    +0179 % Sequence and SMILES
    +0180 outTable = [sequences(:)'; smiles(:)'];
    +0181 
    +0182 fID = fopen(filename,'w');
    +0183 fprintf(fID,'Protein Sequence,Substrate\n');
    +0184 fprintf(fID,'%s,%s\n', outTable{:});
    +0185 fclose(fID);
    +0186 fprintf('OpenKineticsPredictor input stored at %s\n', filename);
    +0187 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/geckomat/change_model/applyComplexData.html b/doc/src/geckomat/change_model/applyComplexData.html deleted file mode 100644 index 7275ed19..00000000 --- a/doc/src/geckomat/change_model/applyComplexData.html +++ /dev/null @@ -1,249 +0,0 @@ - - - - Description of applyComplexData - - - - - - - - - -
    Home > src > geckomat > change_model > applyComplexData.m
    - - - -

    applyComplexData -

    - -

    PURPOSE ^

    -
    applyComplexData
    - -

    SYNOPSIS ^

    -
    function [model, foundComplex, proposedComplex] = applyComplexData(model, complexInfo, modelAdapter, verbose)
    - -

    DESCRIPTION ^

    -
     applyComplexData
    -   Apply stochiometry for complex in an ecModel
    -
    - Input:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   complexInfo     structure as generated by getComplexData. If nothing
    -                   is provided, an attempt will be made to read
    -                   data/ComplexPortal.json from the obj.params.path folder
    -                   specified in the modelAdapter.
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -                   default model adapter).
    -   verbose         logical if a summary should be shown in the Command
    -                   Window (Optional, default true)
    -
    - Output:
    -   model           ecModel where model.ec.rxnEnzMat is populated with
    -                   subunit stochiometries
    -   foundComplex    complexes that fully matched between the model and the
    -                   complex data
    -   proposedComplex complexes where the model contained >75% but <100% of
    -                   the proteins indicated by Complex Portal, or where the
    -                   model contained more proteins than indicated for that
    -                   complex in Complex Portal.
    -
    - Usage:
    -   [model, foundComplex, proposedComplex] = applyComplexData(ecModel, complexInfo, modelAdapter);
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: - -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function [model, foundComplex, proposedComplex] = applyComplexData(model, complexInfo, modelAdapter, verbose)
    -0002 % applyComplexData
    -0003 %   Apply stochiometry for complex in an ecModel
    -0004 %
    -0005 % Input:
    -0006 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0007 %   complexInfo     structure as generated by getComplexData. If nothing
    -0008 %                   is provided, an attempt will be made to read
    -0009 %                   data/ComplexPortal.json from the obj.params.path folder
    -0010 %                   specified in the modelAdapter.
    -0011 %   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -0012 %                   default model adapter).
    -0013 %   verbose         logical if a summary should be shown in the Command
    -0014 %                   Window (Optional, default true)
    -0015 %
    -0016 % Output:
    -0017 %   model           ecModel where model.ec.rxnEnzMat is populated with
    -0018 %                   subunit stochiometries
    -0019 %   foundComplex    complexes that fully matched between the model and the
    -0020 %                   complex data
    -0021 %   proposedComplex complexes where the model contained >75% but <100% of
    -0022 %                   the proteins indicated by Complex Portal, or where the
    -0023 %                   model contained more proteins than indicated for that
    -0024 %                   complex in Complex Portal.
    -0025 %
    -0026 % Usage:
    -0027 %   [model, foundComplex, proposedComplex] = applyComplexData(ecModel, complexInfo, modelAdapter);
    -0028 
    -0029 if nargin < 4 || isempty(verbose)
    -0030     verbose = true;
    -0031 end
    -0032 
    -0033 if nargin < 3 || isempty(modelAdapter)
    -0034     modelAdapter = ModelAdapterManager.getDefault();
    -0035     if isempty(modelAdapter)
    -0036         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0037     end
    -0038 end
    -0039 params = modelAdapter.params;
    -0040 
    -0041 if nargin<2 || isempty(complexInfo)
    -0042     complexInfo = fullfile(params.path,'data','ComplexPortal.json');
    -0043     if ~isfile(complexInfo)
    -0044         complexInfo = getComplexData([], modelAdapter);
    -0045     end
    -0046 end
    -0047 
    -0048 if ischar(complexInfo) || isstring(complexInfo)
    -0049     jsonStr = fileread(complexInfo);
    -0050     complexData = jsondecode(jsonStr);
    -0051 else
    -0052     complexData = complexInfo;
    -0053 end
    -0054 
    -0055 %Remove prefixes on rxn names for gecko light
    -0056 if ~model.ec.geckoLight
    -0057     rxnNames = model.ec.rxns;
    -0058 else
    -0059     rxnNames = extractAfter(model.ec.rxns,4);
    -0060 end
    -0061 
    -0062 foundComplex = cell(numel(rxnNames),7);
    -0063 foundComplexCount = 0;
    -0064 proposedComplex = cell(numel(rxnNames)*2,8); % Might propose more
    -0065 proposedComplexCount = 0;
    -0066 
    -0067 complexProts = repmat({''}, numel({complexData.complexID})*10, 1);
    -0068 complexMatrix = zeros(numel({complexData.complexID}),numel(complexProts));
    -0069 lastProt = 0;
    -0070 for i=1:size(complexMatrix,1)
    -0071     % Locate proteins (and add if new)
    -0072     protIDs     = complexData(i).protID;
    -0073     [isOld, protMatIdx] = ismember(protIDs,complexProts);
    -0074     newProts    = protIDs(~isOld);
    -0075     complexProts(lastProt+1:lastProt+numel(newProts))=newProts;
    -0076     protMatIdx(~isOld)  = lastProt+1 : lastProt+numel(newProts);
    -0077     lastProt = lastProt + numel(newProts);
    -0078     % Add subunit numbers
    -0079     if all(complexData(i).stochiometry == 0)
    -0080         complexData(i).stochiometry(:) = 1;
    -0081     end
    -0082     complexMatrix(i,protMatIdx) = complexData(i).stochiometry;
    -0083 end
    -0084 
    -0085 % Remove excess space
    -0086 complexMatrix(:,lastProt+1:end) = [];
    -0087 complexProts(lastProt+1:end) = [];
    -0088 progressbar('Assign complexes to reactions')
    -0089 for i = 1:numel(rxnNames)
    -0090     % Get the proteins from the model
    -0091     modelProts = model.ec.enzymes(find(model.ec.rxnEnzMat(i,:)));
    -0092     [protsInMat, protsIdx] = ismember(modelProts,complexProts);
    -0093     if ~any(protsInMat)
    -0094         continue
    -0095     end
    -0096     % Find complexes that includes the model proteins
    -0097     [potComplex,~] = find(complexMatrix(:,protsIdx(protsInMat)));
    -0098     potComplex = unique(potComplex);
    -0099     % Some stats on number of subunits, percentage match etc.
    -0100     matchComplexUnits = sum(logical(complexMatrix(potComplex,protsIdx(protsInMat))),2);
    -0101     totalComplexUnits = sum(logical(complexMatrix(potComplex,:)),2);
    -0102     modComplexUnits = numel(modelProts);
    -0103     percMatch  = matchComplexUnits/modComplexUnits;
    -0104     totalMatch = totalComplexUnits/modComplexUnits;
    -0105     if any(percMatch == 1 & totalMatch == 1)
    -0106         % Exact match
    -0107         complexMatch = find(percMatch == 1 & totalMatch == 1);
    -0108         if numel(complexMatch)>1 % If more than one match, take first match
    -0109             complexMatch = complexMatch(1);
    -0110         end
    -0111         complexMatch = potComplex(complexMatch);
    -0112         foundComplexCount = foundComplexCount + 1;
    -0113         foundComplex{foundComplexCount,1} = model.ec.rxns{i};
    -0114         foundComplex{foundComplexCount,2} = complexData(complexMatch).complexID;
    -0115         foundComplex{foundComplexCount,3} = complexData(complexMatch).name;
    -0116         foundComplex{foundComplexCount,4} = complexData(complexMatch).geneName;
    -0117         foundComplex{foundComplexCount,5} = modelProts;
    -0118         foundComplex{foundComplexCount,6} = complexData(complexMatch).protID;
    -0119         foundComplex{foundComplexCount,7} = complexData(complexMatch).stochiometry;
    -0120 
    -0121         % Apply in rxnEnzMat
    -0122         [~, modelProtsIdx] = ismember(modelProts, model.ec.enzymes);
    -0123         model.ec.rxnEnzMat(i,modelProtsIdx) = complexData(complexMatch).stochiometry;
    -0124     
    -0125     elseif modComplexUnits > 1 % Only suggest potential complex if grRule > 1 protein
    -0126         moreUnitsInData = find(percMatch == 1 & totalMatch > 1);
    -0127         if any(moreUnitsInData)
    -0128             % All ecModel subunits match, but Complex Portal has more subunits
    -0129             % Take the complex with the minimum number of extra subunits
    -0130             [~,propComplex] = min(totalMatch(moreUnitsInData));
    -0131             propComplex     = moreUnitsInData(propComplex);
    -0132             selectComplex   = potComplex(propComplex);
    -0133             proposedComplexCount = proposedComplexCount + 1;
    -0134             proposedComplex{proposedComplexCount,1} = model.ec.rxns{i};
    -0135             proposedComplex{proposedComplexCount,2} = complexData(selectComplex).complexID;
    -0136             proposedComplex{proposedComplexCount,3} = complexData(selectComplex).name;
    -0137             proposedComplex{proposedComplexCount,4} = complexData(selectComplex).geneName;
    -0138             proposedComplex{proposedComplexCount,5} = modelProts;
    -0139             proposedComplex{proposedComplexCount,6} = complexData(selectComplex).protID;
    -0140             proposedComplex{proposedComplexCount,7} = complexData(selectComplex).stochiometry;
    -0141             proposedComplex{proposedComplexCount,8} = totalMatch(propComplex)*100;
    -0142         end
    -0143         otherUnits = find(percMatch >= 0.75 & percMatch < 1 & totalMatch <= 1);
    -0144         if any(otherUnits)
    -0145             % At least 75% of ecModels subunits match, Complex Portal maybe have less or different subunits
    -0146             % Take the complex with highest % match.
    -0147             [~,propComplex] = max(percMatch(otherUnits));
    -0148             propComplex     = otherUnits(propComplex);
    -0149             selectComplex   = potComplex(propComplex);
    -0150             proposedComplexCount = proposedComplexCount + 1;
    -0151             proposedComplex{proposedComplexCount,1} = model.ec.rxns{i};
    -0152             proposedComplex{proposedComplexCount,2} = complexData(selectComplex).complexID;
    -0153             proposedComplex{proposedComplexCount,3} = complexData(selectComplex).name;
    -0154             proposedComplex{proposedComplexCount,4} = complexData(selectComplex).geneName;
    -0155             proposedComplex{proposedComplexCount,5} = modelProts;
    -0156             proposedComplex{proposedComplexCount,6} = complexData(selectComplex).protID;
    -0157             proposedComplex{proposedComplexCount,7} = complexData(selectComplex).stochiometry;
    -0158             proposedComplex{proposedComplexCount,8} = percMatch(propComplex)*100;
    -0159         end
    -0160     end
    -0161     progressbar(i/numel(rxnNames))    
    -0162 end
    -0163 progressbar(1) % Make sure it closes
    -0164 
    -0165 % Remove empty space
    -0166 foundComplex(foundComplexCount+1:end,:) = [];
    -0167 proposedComplex(proposedComplexCount+1:end,:) = [];
    -0168 
    -0169 rowHeadings = {'rxn', 'complexID','name','genes','protID_model','protID_complex','stochiometry'};
    -0170 
    -0171 foundComplex = cell2table(foundComplex, 'VariableNames', rowHeadings);
    -0172 
    -0173 proposedComplex = cell2table(proposedComplex, 'VariableNames', [rowHeadings 'match']);
    -0174 if verbose
    -0175     disp(['A total of ' int2str(numel(foundComplex(:,1))) ' complex have full match, and ' int2str(numel(proposedComplex(:,1))) ' proposed.'])
    -0176 end
    -0177 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/change_model/applyCustomKcats.html b/doc/src/geckomat/change_model/applyCustomKcats.html deleted file mode 100644 index 05122e7b..00000000 --- a/doc/src/geckomat/change_model/applyCustomKcats.html +++ /dev/null @@ -1,313 +0,0 @@ - - - - Description of applyCustomKcats - - - - - - - - - -
    Home > src > geckomat > change_model > applyCustomKcats.m
    - - - -

    applyCustomKcats -

    - -

    PURPOSE ^

    -
    applyCustomKcats
    - -

    SYNOPSIS ^

    -
    function [model, rxnUpdated, notMatch] = applyCustomKcats(model, customKcats, modelAdapter)
    - -

    DESCRIPTION ^

    -
     applyCustomKcats
    -   Apply user defined kcats.  Reads data/customKcats.tsv in the obj.params.path
    -   specified in the model adapter. Alternatively, a customKcats structure can
    -   provided, as specified below.
    -
    - Input:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   customKcats     structure with custom kcat information. If nothing
    -                   is provided, an attempt will be made to read
    -                   data/customKcats.tsv from the obj.params.path folder
    -                   specified in the modelAdapter.
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -                   default model adapter).
    -
    - Output:
    -   model           ecModel where kcats for defined proteins have been
    -                   changed
    -   rxnUpdated      ids list of updated reactions, new kcats were applied
    -   notMatch        table with the list of reactions which the custom
    -                   information provided does not have full match (> 50%)
    -                   based on GPR rules. Then, they are suggested to be
    -                   curated by the user
    -
    -   customKcats structure:
    -   - proteins    protein identifiers, multiple for the same kcat (in case
    -                 of a protein complex) are separated by ' + '
    -   - genes       gene identifiers (optional, not used in matching)
    -   - gene_name   short gene name (optional, not used in matching)
    -   - kcat        new kcat value (one per entry)
    -   - rxns        reaction identifiers, multiple for the same kcat are
    -                 separated by ',' (see further explanation below)
    -   - notes       will be appended to model.ec.notes (optional)
    -   - stoicho     complex stoichiometry, separated by ' + ' (examples: '1'
    -                 or '3 + 1'), matching the order in proteins field
    -   
    -   Matching order:
    -   (1) reactions are identified by .proteins and .rxns
    -   (2) reactions are identified by .proteins only (empty .rxns entry)
    -       no additional checks are made: is a reaction annotated with these
    -       proteins? => its kcat will be updated, irrespective of the exact
    -       reaction, direction, substrate, etc.
    -   (3) reactions are identified by .rxns only (empty .proteins entry)
    -       no additional checks are made: is a reaction derived from the
    -       original reaction identifier => its kcat will be updated,
    -       irrespective of the annotated protein
    -
    -   customKcats.rxns field:
    -   The reaction identifiers are from the ORIGINAL model, before _EXP_
    -   suffixes were added by makeEcModel. Reaction directionality IS however
    -   specified, with a _REV suffix.
    -   Example entries:
    -   'r_0001'     will match r_0001, r_0001_EXP_1, r_0001_EXP_2 etc., but
    -                not r_0001_REV, r_0001_EXP_1_REV etc.
    -   'r_0001_REV' will match r_0001_REV, r_0001_EXP_1_REV, r_0001_EXP_2_REV,
    -                etc., but not r_0001, r_0001_EXP_1 etc.
    -   Multiple identifiers should be comma separated (e.g. r_0001, r_0002)
    -
    - Usage:
    -   [model, rxnUpdated, notMatch] = applyCustomKcats(model, customKcats, modelAdapter);
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: - -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function [model, rxnUpdated, notMatch] = applyCustomKcats(model, customKcats, modelAdapter)
    -0002 % applyCustomKcats
    -0003 %   Apply user defined kcats.  Reads data/customKcats.tsv in the obj.params.path
    -0004 %   specified in the model adapter. Alternatively, a customKcats structure can
    -0005 %   provided, as specified below.
    -0006 %
    -0007 % Input:
    -0008 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0009 %   customKcats     structure with custom kcat information. If nothing
    -0010 %                   is provided, an attempt will be made to read
    -0011 %                   data/customKcats.tsv from the obj.params.path folder
    -0012 %                   specified in the modelAdapter.
    -0013 %   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -0014 %                   default model adapter).
    -0015 %
    -0016 % Output:
    -0017 %   model           ecModel where kcats for defined proteins have been
    -0018 %                   changed
    -0019 %   rxnUpdated      ids list of updated reactions, new kcats were applied
    -0020 %   notMatch        table with the list of reactions which the custom
    -0021 %                   information provided does not have full match (> 50%)
    -0022 %                   based on GPR rules. Then, they are suggested to be
    -0023 %                   curated by the user
    -0024 %
    -0025 %   customKcats structure:
    -0026 %   - proteins    protein identifiers, multiple for the same kcat (in case
    -0027 %                 of a protein complex) are separated by ' + '
    -0028 %   - genes       gene identifiers (optional, not used in matching)
    -0029 %   - gene_name   short gene name (optional, not used in matching)
    -0030 %   - kcat        new kcat value (one per entry)
    -0031 %   - rxns        reaction identifiers, multiple for the same kcat are
    -0032 %                 separated by ',' (see further explanation below)
    -0033 %   - notes       will be appended to model.ec.notes (optional)
    -0034 %   - stoicho     complex stoichiometry, separated by ' + ' (examples: '1'
    -0035 %                 or '3 + 1'), matching the order in proteins field
    -0036 %
    -0037 %   Matching order:
    -0038 %   (1) reactions are identified by .proteins and .rxns
    -0039 %   (2) reactions are identified by .proteins only (empty .rxns entry)
    -0040 %       no additional checks are made: is a reaction annotated with these
    -0041 %       proteins? => its kcat will be updated, irrespective of the exact
    -0042 %       reaction, direction, substrate, etc.
    -0043 %   (3) reactions are identified by .rxns only (empty .proteins entry)
    -0044 %       no additional checks are made: is a reaction derived from the
    -0045 %       original reaction identifier => its kcat will be updated,
    -0046 %       irrespective of the annotated protein
    -0047 %
    -0048 %   customKcats.rxns field:
    -0049 %   The reaction identifiers are from the ORIGINAL model, before _EXP_
    -0050 %   suffixes were added by makeEcModel. Reaction directionality IS however
    -0051 %   specified, with a _REV suffix.
    -0052 %   Example entries:
    -0053 %   'r_0001'     will match r_0001, r_0001_EXP_1, r_0001_EXP_2 etc., but
    -0054 %                not r_0001_REV, r_0001_EXP_1_REV etc.
    -0055 %   'r_0001_REV' will match r_0001_REV, r_0001_EXP_1_REV, r_0001_EXP_2_REV,
    -0056 %                etc., but not r_0001, r_0001_EXP_1 etc.
    -0057 %   Multiple identifiers should be comma separated (e.g. r_0001, r_0002)
    -0058 %
    -0059 % Usage:
    -0060 %   [model, rxnUpdated, notMatch] = applyCustomKcats(model, customKcats, modelAdapter);
    -0061 
    -0062 if nargin < 3 || isempty(modelAdapter)
    -0063     modelAdapter = ModelAdapterManager.getDefault();
    -0064     if isempty(modelAdapter)
    -0065         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0066     end
    -0067 end
    -0068 
    -0069 params = modelAdapter.params;
    -0070 
    -0071 if nargin<2 || isempty(customKcats)
    -0072     customKcats = fullfile(params.path,'data','customKcats.tsv');
    -0073 end
    -0074 if isstruct(customKcats)
    -0075     if ~all(isfield(customKcats,{'proteins','kcat','rxns'}))
    -0076         error('The customKcats structure does not have all essential fields.');
    -0077     end
    -0078 elseif isfile(customKcats)
    -0079     fID = fopen(customKcats, 'r');
    -0080     fileContent = textscan(fID, '%s %s %s %f %q %s %s', 'Delimiter', '\t', 'HeaderLines', 1);
    -0081     fclose(fID);
    -0082     clear customKcats
    -0083     customKcats.proteins    = fileContent{1};
    -0084     customKcats.genes       = fileContent{2};
    -0085     customKcats.gene_name   = fileContent{3};
    -0086     customKcats.kcat        = fileContent{4};
    -0087     customKcats.rxns        = fileContent{5};
    -0088     customKcats.notes       = fileContent{6};
    -0089     customKcats.stoicho     = fileContent{7};
    -0090 else
    -0091     error(['Cannot find file: ' customKcats]);
    -0092 end
    -0093 
    -0094 rxnToUpdate = false(length(model.ec.rxns),1);
    -0095 rxnNotMatch = false(length(model.ec.rxns),1);
    -0096 evaluatedRule = cell(length(model.ec.rxns),1);
    -0097 enzInModel = cell(length(model.ec.rxns),1);
    -0098 ecRxnNoSuffix = regexprep(model.ec.rxns,'_EXP_\d+$','');
    -0099 
    -0100 % Implementation for full GECKO formulation
    -0101 if ~model.ec.geckoLight
    -0102     for i = 1:numel(customKcats.proteins)
    -0103         if isempty(customKcats.proteins{i})
    -0104             %If only reaction ID(s) is/are specified (and no proteins),
    -0105             %then apply the kcat to all isozymic reactions
    -0106             rxns    = strtrim(strsplit(customKcats.rxns{i}, ','));
    -0107             rxnIdxs = ismember(ecRxnNoSuffix,rxns);
    -0108             rxnToUpdate(rxnIdxs) = 1;
    -0109             model.ec.kcat(rxnIdxs) = customKcats.kcat(i);
    -0110         else
    -0111             prots = strtrim(strsplit(customKcats.proteins{i}, '+'));
    -0112 
    -0113             % Find the index for the enzymes which kcat will be changed. In
    -0114             % case the protein is not in the model generate a warning.
    -0115             try
    -0116                 enzIdx = cellfun(@(x) find(strcmpi(model.ec.enzymes, x)), prots);
    -0117             catch
    -0118                 enzIdx = [];
    -0119                 printOrange(['WARNING: Protein(s) ' customKcats.proteins{i} ' were not found in the model.']);
    -0120             end
    -0121 
    -0122             % if not specific reactions are defined, find all the reaction
    -0123             % index where the enzyme is used
    -0124             if isempty(customKcats.rxns{i})
    -0125                 temp_rxnIdxs = arrayfun(@(x) find(model.ec.rxnEnzMat(:, x)), enzIdx, 'UniformOutput', false);
    -0126                 % otherwhise, If a set of reactions if defined, only get the index for those
    -0127                 % but ignore any _EXP_ suffixes
    -0128             else
    -0129                 rxns = strtrim(strsplit(customKcats.rxns{i}, ','));
    -0130                 temp_rxnIdxs = arrayfun(@(x) find(strcmpi(ecRxnNoSuffix, x)), rxns, 'UniformOutput', false);
    -0131             end
    -0132 
    -0133             if ~isempty(temp_rxnIdxs)
    -0134                 rxnIdxs = [];
    -0135                 for j = 1:numel(temp_rxnIdxs)
    -0136                     rxnIdxs = [rxnIdxs; temp_rxnIdxs{j}];
    -0137                 end
    -0138 
    -0139                 % Check when multiple proteins are involved, since it can return same rxn n times
    -0140                 rxnIdxs = unique(rxnIdxs); %unique(rxnIdxs{1, :});
    -0141 
    -0142                 for j = 1:numel(rxnIdxs)
    -0143                     % Get all the enzymes involved in the reaction
    -0144                     allEnzInRxn = find(model.ec.rxnEnzMat(rxnIdxs(j),:));
    -0145 
    -0146                     C = intersect(enzIdx, allEnzInRxn);
    -0147 
    -0148                     % Determine the match percentage bewteen the rules
    -0149                     if numel(C) == numel(enzIdx) && numel(C) == numel(allEnzInRxn)
    -0150                         match = 1;
    -0151                     else
    -0152                         if numel(enzIdx) < numel(allEnzInRxn)
    -0153                             match = numel(C) / numel(allEnzInRxn);
    -0154                         else
    -0155                             match = numel(C) / numel(enzIdx);
    -0156                         end
    -0157                     end
    -0158 
    -0159                     % Update the kcat value stored in the model, if match 100%,
    -0160                     % otherwhise if >= 0.5 inform to the user to be validated
    -0161                     if match == 1
    -0162                         rxnToUpdate(rxnIdxs(j)) = 1;
    -0163                         model.ec.kcat(rxnIdxs(j)) = customKcats.kcat(i);
    -0164 
    -0165                         % Add note mentioning manual kcat change
    -0166                         model.ec.source{rxnIdxs(j),1} = 'custom';
    -0167                         if isfield(customKcats,'notes')
    -0168                             if isempty(model.ec.notes{rxnIdxs(j), 1}) && ~isempty(customKcats.notes{i})
    -0169                                 model.ec.notes{rxnIdxs(j), 1} = customKcats.notes{i};
    -0170                             else
    -0171                                 model.ec.notes{rxnIdxs(j), 1} = [model.ec.notes{rxnIdxs(j), 1} ', ' customKcats.notes{i}];
    -0172                             end
    -0173                         end
    -0174                     elseif match >= 0.5 && match < 1
    -0175                         rxnNotMatch(rxnIdxs(j)) = 1;
    -0176                         evaluatedRule{rxnIdxs(j), 1} = customKcats.proteins{i};
    -0177                         enzInModel{rxnIdxs(j), 1} = strjoin(model.ec.enzymes(allEnzInRxn), ' + ');
    -0178                     end
    -0179                 end
    -0180             end
    -0181         end
    -0182     end
    -0183 
    -0184     % Apply the new kcat values to the model
    -0185     if ~isempty(find(rxnToUpdate, 1))
    -0186         model = applyKcatConstraints(model, rxnToUpdate);
    -0187     else
    -0188         printOrange('WARNING: No matches found. Consider checking the IDs or proteins in customKcats.');
    -0189     end
    -0190 
    -0191     rxnUpdated = model.ec.rxns(find(rxnToUpdate));
    -0192 
    -0193     % Remove from notMatch those reactions already updated
    -0194     remove = and(rxnToUpdate, rxnNotMatch);
    -0195     rxnNotMatch(remove) = 0;
    -0196     evaluatedRule(remove) = '';
    -0197     enzInModel(remove) = '';
    -0198 
    -0199     idRxns = model.ec.rxns(find(rxnNotMatch));
    -0200     fullIdx = cellfun(@(x) find(strcmpi(model.rxns, x)), idRxns);
    -0201     rxnsNames = model.rxnNames(fullIdx);
    -0202     evaluatedRule = evaluatedRule(~cellfun('isempty', evaluatedRule));
    -0203     enzInModel = enzInModel(~cellfun('isempty', enzInModel));
    -0204     rules = model.grRules(fullIdx);
    -0205     notMatch = table(idRxns, rxnsNames, evaluatedRule, enzInModel, rules, ...
    -0206         'VariableNames',{'rxns', 'name', 'custom enzymes', 'enzymes in model', 'rules'});
    -0207 end
    -0208 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/change_model/applyKcatConstraints.html b/doc/src/geckomat/change_model/applyKcatConstraints.html deleted file mode 100644 index a36e0e3b..00000000 --- a/doc/src/geckomat/change_model/applyKcatConstraints.html +++ /dev/null @@ -1,183 +0,0 @@ - - - - Description of applyKcatConstraints - - - - - - - - - -
    Home > src > geckomat > change_model > applyKcatConstraints.m
    - - - -

    applyKcatConstraints -

    - -

    PURPOSE ^

    -
    applyKcatConstraints
    - -

    SYNOPSIS ^

    -
    function model = applyKcatConstraints(model,updateRxns)
    - -

    DESCRIPTION ^

    -
     applyKcatConstraints
    -   Applies kcat-derived enzyme constraints to an ecModel. Existing enzyme
    -   constraints are first removed (unless updateRxns is provided), and new
    -   constraints are defined based on the content of model.ec.kcat.
    -
    - Input:
    -   model       an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   updateRxns  if not all enzyme constraints should be updated, this can
    -               be given as either a logical vector of length
    -               model.ec.rxns, a vector of model.ec.rxns indices, or a
    -               (cell array of) string(s) with model.ec.rxns identifiers.
    -               For light models, these reactions should match model.rxns.
    -
    - Output:
    -   model       ecModel where reactions are constrained by enzyme usage
    -               if a kcat value was provided for the reaction-enzyme pair
    -               in model.ec.kcat
    -
    - Usage: model = applyKcatConstraints(model,updateRxns);
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: - - - - - -

    SOURCE CODE ^

    -
    0001 function model = applyKcatConstraints(model,updateRxns)
    -0002 % applyKcatConstraints
    -0003 %   Applies kcat-derived enzyme constraints to an ecModel. Existing enzyme
    -0004 %   constraints are first removed (unless updateRxns is provided), and new
    -0005 %   constraints are defined based on the content of model.ec.kcat.
    -0006 %
    -0007 % Input:
    -0008 %   model       an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0009 %   updateRxns  if not all enzyme constraints should be updated, this can
    -0010 %               be given as either a logical vector of length
    -0011 %               model.ec.rxns, a vector of model.ec.rxns indices, or a
    -0012 %               (cell array of) string(s) with model.ec.rxns identifiers.
    -0013 %               For light models, these reactions should match model.rxns.
    -0014 %
    -0015 % Output:
    -0016 %   model       ecModel where reactions are constrained by enzyme usage
    -0017 %               if a kcat value was provided for the reaction-enzyme pair
    -0018 %               in model.ec.kcat
    -0019 %
    -0020 % Usage: model = applyKcatConstraints(model,updateRxns);
    -0021 
    -0022 %these lines are for the nargin lines below only
    -0023 if (model.ec.geckoLight)
    -0024     rxns = model.rxns;
    -0025 else
    -0026     rxns = model.ec.rxns;
    -0027 end
    -0028 
    -0029 if nargin<2
    -0030     updateRxns = true(numel(rxns),1);
    -0031 elseif isnumeric(updateRxns)
    -0032     updateRxnsLog = false(numel(rxns),1);
    -0033     updateRxnsLog(updateRxns) = true;
    -0034     updateRxns = updateRxnsLog;
    -0035 elseif iscellstr(updateRxns) || ischar(updateRxns) || isstring(updateRxns)
    -0036     updateRxnsIds = convertCharArray(updateRxns);
    -0037     updateRxns = ismember(rxns,updateRxnsIds);
    -0038 end
    -0039  
    -0040 if isempty(find(updateRxns, 1)) || isempty(updateRxns)
    -0041      error('No reaction to update or updateRxns is logical but without any true value')
    -0042 end
    -0043 
    -0044 if ~isfield(model,'ec')
    -0045     error(['No model.ec structure could be found: the provided model is'...
    -0046            ' not a valid GECKO3 ecModel. First run makeEcModel(model).'])
    -0047 end
    -0048 if all(model.ec.kcat==0)
    -0049     printOrange('WARNING: No kcat values are provided in model.ec.kcat, model remains unchanged.\n');
    -0050     return
    -0051 end
    -0052 
    -0053 %Clear existing incorporation of enzyme usage
    -0054 if ~model.ec.geckoLight
    -0055     protMetIdx = startsWith(model.mets,'prot_') & ~strcmp(model.mets,'prot_pool');
    -0056     metabolRxn = unique(model.ec.rxns(updateRxns));
    -0057     metabolRxn = ismember(model.rxns,metabolRxn);
    -0058     model.S(protMetIdx,metabolRxn) = 0;
    -0059 end %no clearing needed for GECKO Light, will be overwritten below
    -0060 %For normal GECKO formulation (full model), where each enzyme is explicitly considered
    -0061 if ~model.ec.geckoLight 
    -0062     %Column 1 = rxn idx; 2 = enzyme idx; 3 = subunit copies; 4 = kcat; 5 = MW
    -0063     newKcats=zeros(numel(updateRxns)*10,5);
    -0064     updateRxns=find(updateRxns);
    -0065     kcatFirst=0;
    -0066     for i=1:numel(updateRxns)
    -0067         j=updateRxns(i);
    -0068         if model.ec.kcat(j) ~= 0
    -0069             enzymes   = find(model.ec.rxnEnzMat(j,:));
    -0070             kcatLast  = kcatFirst+numel(enzymes);
    -0071             kcatFirst = kcatFirst+1;
    -0072             newKcats(kcatFirst:kcatLast,1) = j;
    -0073             newKcats(kcatFirst:kcatLast,2) = enzymes;
    -0074             newKcats(kcatFirst:kcatLast,3) = model.ec.rxnEnzMat(j,enzymes);
    -0075             newKcats(kcatFirst:kcatLast,4) = model.ec.kcat(j);
    -0076             newKcats(kcatFirst:kcatLast,5) = model.ec.mw(enzymes);
    -0077             kcatFirst = kcatLast;
    -0078         end
    -0079     end
    -0080     if exist('kcatLast','var') % If it does not, then no kcats are found
    -0081         newKcats(kcatLast+1:end,:)=[];
    -0082 
    -0083         sel = newKcats(:,4) > 0; %Only apply to non-zero kcat
    -0084         newKcats(sel,4) = newKcats(sel,4) * 3600; %per second -> per hour
    -0085         newKcats(sel,4) = newKcats(sel,5) ./ newKcats(sel,4); %MW/kcat
    -0086         newKcats(sel,4) = newKcats(sel,3) .* newKcats(sel,4); %Multicopy subunits.
    -0087         newKcats(~sel,4) = 0; %Results in zero-cost
    -0088 
    -0089         %Replace rxns and enzymes with their location in model
    -0090         [~,newKcats(:,1)] = ismember(model.ec.rxns(newKcats(:,1)),model.rxns);
    -0091         [~,newKcats(:,2)] = ismember(strcat('prot_',model.ec.enzymes(newKcats(:,2))),model.mets);
    -0092         linearIndices     = sub2ind(size(model.S),newKcats(:,2),newKcats(:,1));
    -0093         model.S(linearIndices) = -newKcats(:,4); %Substrate = negative
    -0094     end
    -0095 else %GECKO light formulation, where prot_pool represents all usages
    -0096     prot_pool_idx = find(ismember(model.mets,'prot_pool'));
    -0097     %first remove the prefix of all rxns
    -0098     modRxns     = extractAfter(model.ec.rxns,4);
    -0099     % Map ec-reactions to model.rxns
    -0100     [hasEc,~]   = ismember(model.rxns,modRxns);
    -0101     hasEc       = find(hasEc & updateRxns);
    -0102     [~,rxnIdx]   = ismember(modRxns,model.rxns);
    -0103     for i = 1:numel(hasEc)
    -0104         % Get all isozymes per reaction
    -0105         ecIdx = find(rxnIdx == hasEc(i));
    -0106         % ecIdx = strcmp(model.rxns(hasEc(i)),modRxns);
    -0107         % Multiply enzymes with their MW (they are then automatically
    -0108         % summed per reaction), and divide by their kcat, to get a vector
    -0109         % of MW/kcat values.
    -0110         MWkcat = (model.ec.rxnEnzMat(ecIdx,:) * model.ec.mw) ./ model.ec.kcat(ecIdx);
    -0111         % If kcat was zero, MWkcat is Inf. If no enzyme info was found,
    -0112         % MWkcat is NaN. Correct both back to zero
    -0113         MWkcat(isinf(MWkcat) | isnan(MWkcat)) = 0;
    -0114         % Select the lowest MW/kcat (= most efficient), and convert to /hour
    -0115         model.S(prot_pool_idx, hasEc(i)) = -min(MWkcat/3600);
    -0116     end
    -0117 end
    -0118 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/change_model/findMetSmiles.html b/doc/src/geckomat/change_model/findMetSmiles.html deleted file mode 100644 index afe8697b..00000000 --- a/doc/src/geckomat/change_model/findMetSmiles.html +++ /dev/null @@ -1,170 +0,0 @@ - - - - Description of findMetSmiles - - - - - - - - - -
    Home > src > geckomat > change_model > findMetSmiles.m
    - - - -

    findMetSmiles -

    - -

    PURPOSE ^

    -
    findMetSMILES
    - -

    SYNOPSIS ^

    -
    function [model,noSMILES] = findMetSmiles(model, modelAdapter, verbose)
    - -

    DESCRIPTION ^

    -
     findMetSMILES
    -   Queries PubChem by metabolite names to obtain SMILES. Matches will also
    -   be stored in tutorials/***/data/smilesDB.tsv, that will also be queried
    -   first next time the function is run. If the model already has a
    -   metSmiles field, then non-empty entries will not be overwritten.
    -
    - Input:
    -   model        a model whose metNames field is used to find the relevant SMILES
    -   modelAdapter a loaded model adapter (Optional, will otherwise use the
    -                default model adapter).
    -   verbose      logical whether progress should be reported (Optional,
    -                default true)
    - Ouput:
    -   model        model with model.metSmiles specified.
    -   noSMILES     metabolite names for which no SMILES could be found.
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function [model,noSMILES] = findMetSmiles(model, modelAdapter, verbose)
    -0002 % findMetSMILES
    -0003 %   Queries PubChem by metabolite names to obtain SMILES. Matches will also
    -0004 %   be stored in tutorials/***/data/smilesDB.tsv, that will also be queried
    -0005 %   first next time the function is run. If the model already has a
    -0006 %   metSmiles field, then non-empty entries will not be overwritten.
    -0007 %
    -0008 % Input:
    -0009 %   model        a model whose metNames field is used to find the relevant SMILES
    -0010 %   modelAdapter a loaded model adapter (Optional, will otherwise use the
    -0011 %                default model adapter).
    -0012 %   verbose      logical whether progress should be reported (Optional,
    -0013 %                default true)
    -0014 % Ouput:
    -0015 %   model        model with model.metSmiles specified.
    -0016 %   noSMILES     metabolite names for which no SMILES could be found.
    -0017 %
    -0018 if nargin < 3 || isempty(verbose)
    -0019     verbose = true;
    -0020 end
    -0021 if nargin < 2 || isempty(modelAdapter)
    -0022     modelAdapter = ModelAdapterManager.getDefault();
    -0023     if isempty(modelAdapter)
    -0024         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0025     end
    -0026 end
    -0027 params = modelAdapter.params;
    -0028 
    -0029 [uniqueNames, ~, uniqueIdx] = unique(regexprep(model.metNames,'^prot_.*',''));
    -0030 uniqueSmiles(1:numel(uniqueNames),1) = {''};
    -0031 metMatch = false(length(uniqueNames),1);
    -0032 metMatch(strcmp(uniqueNames,'')) = 1; % No need trying to match empty fields
    -0033 if verbose; fprintf('Check for local SMILES database... '); end
    -0034 smilesDBfile = (fullfile(params.path,'data','smilesDB.tsv'));
    -0035 if exist(smilesDBfile,'file')==2
    -0036     fID = fopen(smilesDBfile,'r');
    -0037     raw = textscan(fID,'%s %s','Delimiter','\t','HeaderLines',0);
    -0038     fclose(fID);
    -0039     smilesDB.names = raw{1};
    -0040     smilesDB.smile = raw{2};
    -0041     [metMatch, metIdx] = ismember(uniqueNames,smilesDB.names);
    -0042     uniqueSmiles(metMatch) = smilesDB.smile(metIdx(metMatch));
    -0043     if verbose; fprintf('done.\n'); end
    -0044 else
    -0045     if verbose; fprintf('not found.\n'); end
    -0046 end
    -0047 
    -0048 if any(~metMatch)
    -0049     progressbar('Querying PubChem for SMILES by metabolite names')
    -0050     webOptions = weboptions('Timeout', 30);
    -0051     for i = 1:numel(uniqueNames)
    -0052         if metMatch(i)
    -0053             continue;
    -0054         end
    -0055         retry = 0;
    -0056         while retry < 10
    -0057             try
    -0058                 smileResult       = webread(['https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/' uniqueNames{i} '/property/CanonicalSMILES/TXT'], webOptions);
    -0059                 %Sometimes multiple lines are given, with alternative SMILES. Only
    -0060                 %keep the first suggestion.
    -0061                 smileResult       = regexp(smileResult,'(^\S*)\n','once','tokens');
    -0062                 uniqueSmiles{i,1} = smileResult{1,1};
    -0063                 retry = 15; % success: no retry
    -0064             catch exception
    -0065                 %Sometimes the call fails, for example since the server is busy. In those cases
    -0066                 %we will try 10 times. Some errors however are because the metabolite
    -0067                 %name does no exist in the database (404) or some other error (the metabolite contains
    -0068                 %a slash or similar, 400 or 500). In those cases we can
    -0069                 %immediately give up.
    -0070                 if (strcmp(exception.identifier, 'MATLAB:webservices:HTTP404StatusCodeError') || ...
    -0071                         strcmp(exception.identifier, 'MATLAB:webservices:HTTP400StatusCodeError') || ...
    -0072                         strcmp(exception.identifier, 'MATLAB:webservices:HTTP500StatusCodeError'))
    -0073                     uniqueSmiles(i) = {''};
    -0074                     retry = 15;
    -0075                 else
    -0076                     retry = retry + 1;
    -0077                 end
    -0078             end
    -0079         if retry == 10
    -0080             error('Cannot reach PubChem. Check your internet connection and try again.')
    -0081         end
    -0082         end
    -0083         % Append one line each time, in case internet connection is lost
    -0084         % halfway. Open & close file each time to avoid leaving the file
    -0085         % open when breaking the function.
    -0086         out = [uniqueNames(i), uniqueSmiles(i)];
    -0087         fID = fopen(smilesDBfile,'a');
    -0088         fprintf(fID,'%s\t%s\n',out{:});
    -0089         fclose(fID);
    -0090         progressbar(i/numel(uniqueNames))
    -0091     end
    -0092     if verbose
    -0093         fprintf('Model-specific SMILES database stored at %s\n',smilesDBfile);
    -0094     end
    -0095 end
    -0096 newSmiles = uniqueSmiles(uniqueIdx);
    -0097 noSMILES = cellfun(@isempty,uniqueSmiles);
    -0098 successRatio = 1-(numel(find(noSMILES))/numel(uniqueSmiles));
    -0099 fprintf('SMILES could be found for %s%% of the unique metabolite names.\n',num2str(successRatio*100,'%.0f'))
    -0100 noSMILES = uniqueNames(noSMILES);
    -0101 
    -0102 if ~isfield(model,'metSmiles') || all(cellfun(@isempty,model.metSmiles))
    -0103     model.metSmiles = newSmiles;
    -0104 else
    -0105     emptySmiles = cellfun(@isempty,model.metSmiles);
    -0106     model.metSmiles(emptySmiles) = newSmiles(emptySmiles);
    -0107 end
    -0108 progressbar(1) % Make sure it closes
    -0109 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/change_model/getComplexData.html b/doc/src/geckomat/change_model/getComplexData.html deleted file mode 100644 index 23a5cbbb..00000000 --- a/doc/src/geckomat/change_model/getComplexData.html +++ /dev/null @@ -1,241 +0,0 @@ - - - - Description of getComplexData - - - - - - - - - -
    Home > src > geckomat > change_model > getComplexData.m
    - - - -

    getComplexData -

    - -

    PURPOSE ^

    -
    getComplexData
    - -

    SYNOPSIS ^

    -
    function complexInfo = getComplexData(taxonomicID, modelAdapter)
    - -

    DESCRIPTION ^

    -
     getComplexData
    -   Download curated complex stochiometries from the EMBL-EBI Complex
    -   Portal database. Writes data/ComplexPortal.json in the obj.params.path
    -   specified in the model adapter.
    -
    - Input:
    -   taxonomicID     taxonomic identifier for which complex data should be
    -                   downloaded. Only taxonomic identifiers allowed are
    -                   those included on Complex Portal:
    -                   https://www.ebi.ac.uk/complexportal/complex/organisms
    -                   If empty, no complex data is downloaded, if 0 (zero),
    -                   complex data from all organisms in Complex Portal is
    -                   downloaded.
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -                   default model adapter).
    - Output:
    -   complexInfo     structure with data downloaded from Complex Portal.
    -                   Contains the following fields:
    -                   - complexID: id of the complex on Complex Portal
    -                   - name: name of the complex on Complex Portal
    -                   - species: organism containing the complex
    -                   - geneName: names of the genes in the complex
    -                   - protID: Uniprot IDs of the proteins in the complex
    -                   - stochiometry: the complex stochiometry given in the same
    -                     order as the genes and proteins in geneName and protID
    -                   - defined:  0 if Complex Portal has no defined stochiometry
    -                               1 if defined subunit stochiometry is given
    -                               2 if complex consists of sub-complexes, whose
    -                                 subunit stochiometries are given
    - Usage
    -   complexInfo = getComplexData(organism, modelAdapter);
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: - - - - - -

    SOURCE CODE ^

    -
    0001 function complexInfo = getComplexData(taxonomicID, modelAdapter)
    -0002 % getComplexData
    -0003 %   Download curated complex stochiometries from the EMBL-EBI Complex
    -0004 %   Portal database. Writes data/ComplexPortal.json in the obj.params.path
    -0005 %   specified in the model adapter.
    -0006 %
    -0007 % Input:
    -0008 %   taxonomicID     taxonomic identifier for which complex data should be
    -0009 %                   downloaded. Only taxonomic identifiers allowed are
    -0010 %                   those included on Complex Portal:
    -0011 %                   https://www.ebi.ac.uk/complexportal/complex/organisms
    -0012 %                   If empty, no complex data is downloaded, if 0 (zero),
    -0013 %                   complex data from all organisms in Complex Portal is
    -0014 %                   downloaded.
    -0015 %   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -0016 %                   default model adapter).
    -0017 % Output:
    -0018 %   complexInfo     structure with data downloaded from Complex Portal.
    -0019 %                   Contains the following fields:
    -0020 %                   - complexID: id of the complex on Complex Portal
    -0021 %                   - name: name of the complex on Complex Portal
    -0022 %                   - species: organism containing the complex
    -0023 %                   - geneName: names of the genes in the complex
    -0024 %                   - protID: Uniprot IDs of the proteins in the complex
    -0025 %                   - stochiometry: the complex stochiometry given in the same
    -0026 %                     order as the genes and proteins in geneName and protID
    -0027 %                   - defined:  0 if Complex Portal has no defined stochiometry
    -0028 %                               1 if defined subunit stochiometry is given
    -0029 %                               2 if complex consists of sub-complexes, whose
    -0030 %                                 subunit stochiometries are given
    -0031 % Usage
    -0032 %   complexInfo = getComplexData(organism, modelAdapter);
    -0033 
    -0034 if nargin < 2 || isempty(modelAdapter)
    -0035     modelAdapter = ModelAdapterManager.getDefault();
    -0036     if isempty(modelAdapter)
    -0037         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0038     end
    -0039 end
    -0040 
    -0041 if nargin<1 || isempty(taxonomicID)
    -0042     taxonomicID = modelAdapter.getParameters().complex.taxonomicID;
    -0043 end
    -0044 
    -0045 params = modelAdapter.params;
    -0046 if isempty(taxonomicID) % Can be empty when gathered from model adapter
    -0047     printOrange('WARNING: No taxonomicID specified.');
    -0048     return
    -0049 elseif taxonomicID == 0
    -0050     taxonomicID = [];
    -0051 end
    -0052 
    -0053 webOptions = weboptions('Timeout', 30);
    -0054 try
    -0055     url1 = 'https://www.ebi.ac.uk/intact/complex-ws/search/*';
    -0056     if ~isempty(taxonomicID)
    -0057         url1 = [url1 '?facets=species&filters=species:("' num2str(taxonomicID) '")'];
    -0058     end
    -0059     data = webread(url1,webOptions);
    -0060 catch ME
    -0061     if (strcmp(ME.identifier,'MATLAB:webservices:HTTP404StatusCodeError'))
    -0062         error('Cannot connect to the Complex Portal, perhaps the server is not responding');
    -0063     end
    -0064 end
    -0065 if data.size == 0
    -0066     error('No data could be gathered from Complex Portal for the specified taxonomicID.')
    -0067 end
    -0068 complexData = cell(data.size,7);
    -0069 
    -0070 progressbar('Retrieving information for complexes');
    -0071 for i = 1:data.size
    -0072     progressbar(i/data.size) % Update progress bar
    -0073     url2 = 'https://www.ebi.ac.uk/intact/complex-ws/complex/';
    -0074     complexID = data.elements(i,1).complexAC;
    -0075     try
    -0076         temp = webread([url2 complexID],webOptions);
    -0077     catch ME
    -0078         if (strcmp(ME.identifier,'MATLAB:webservices:HTTP404StatusCodeError'))
    -0079             printOrange(['WARNING: Cannot retrieve the information for ' complexID '.\n']);
    -0080         end
    -0081         temp = [];
    -0082     end
    -0083 
    -0084     if ~isempty(temp)
    -0085         complexData(i,1) = {temp.complexAc};
    -0086         complexData(i,2) = {temp.name};
    -0087         complexData(i,3) = {temp.species};
    -0088 
    -0089         idxIntType = find(strcmpi({temp.participants.interactorType}, 'protein'));
    -0090 
    -0091         % Some complex reported are 'stable complex', then, save the id
    -0092         % complex and but set the genes and protein to a empty string.
    -0093         if numel(idxIntType) > 0
    -0094             complexData(i,4) = {{temp.participants(idxIntType).name}};
    -0095             complexData(i,5) = {{temp.participants(idxIntType).identifier}};
    -0096         else
    -0097             complexData(i,4) = {{temp.participants.name}};
    -0098             complexData(i,5) = {{temp.participants.identifier}};
    -0099         end
    -0100 
    -0101         % Portal complex has two stochiometry values, a minimum and
    -0102         % maximum value. Only minimum will be store. In some cases,
    -0103         % some complex does not have stochiometry coefficient, then, it
    -0104         % will be fill with zeros
    -0105         if ~cellfun('isempty',{temp.participants.stochiometry})
    -0106             % For some reason, if there is only one protein in the complex
    -0107             % split function does nor return a cell nx2, instead is 2x1,
    -0108             % then assign an incorrect stochiometry
    -0109             switch numel(idxIntType)
    -0110                 case 0 % Contains complexes
    -0111                     stochiometry = split({temp.participants.stochiometry}.', ',');
    -0112                     complexData(i,7) = {2};
    -0113                 case 1 % Contains one protein
    -0114                     stochiometry = split({temp.participants(idxIntType).stochiometry}.', ',').';
    -0115                     complexData(i,7) = {1};
    -0116                 otherwise
    -0117                     stochiometry = split({temp.participants(idxIntType).stochiometry}.', ',');
    -0118                     complexData(i,7) = {1};
    -0119             end
    -0120             values = str2double(erase(stochiometry(:,1),"minValue: ")).';
    -0121             complexData(i,6) = {values};
    -0122         else
    -0123             complexData(i,6) = {repelem(0,numel(complexData{i,4}))};
    -0124             complexData(i,7) = {0};
    -0125         end
    -0126     end
    -0127 end
    -0128 fprintf('\n');
    -0129 
    -0130 % Expand complexes of complexes
    -0131 complexComplex = find([complexData{:,7}]==2);
    -0132 if ~isempty(complexComplex)
    -0133     for i=1:numel(complexComplex)
    -0134         subComplex    = complexData{complexComplex(i),5};
    -0135         subComplexS   = complexData{complexComplex(i),6};
    -0136         subComplexIdx = find(ismember(complexData(:,1),subComplex));
    -0137         allGenes = horzcat(complexData{subComplexIdx,4});
    -0138         allProts = horzcat(complexData{subComplexIdx,5});
    -0139         allStoch = {complexData{subComplexIdx,6}};
    -0140         for j=1:numel(subComplex)
    -0141             allStoch{j}=allStoch{j}*subComplexS(j);
    -0142         end
    -0143         allStoch = horzcat(allStoch{:});
    -0144         [allGenes,ia,ic] = unique(allGenes,'stable');
    -0145         allProts = allProts(ia);
    -0146         allStoch = splitapply(@sum, allStoch', ic);
    -0147         complexData{complexComplex(i),4} = allGenes;
    -0148         complexData{complexComplex(i),5} = allProts;
    -0149         complexData{complexComplex(i),6} = allStoch;
    -0150     end
    -0151 end
    -0152 
    -0153 rowHeadings = {'complexID','name','species','geneName','protID','stochiometry','defined'};
    -0154 
    -0155 complexInfo = cell2struct(complexData, rowHeadings, 2);
    -0156 
    -0157 % Convert to a JSON file
    -0158 jsontxt = jsonencode(cell2table(complexData, 'VariableNames', rowHeadings));
    -0159 % Write to a JSON file
    -0160 fid = fopen(fullfile(params.path,'data','ComplexPortal.json'), 'w');
    -0161 fprintf(fid, '%s', jsontxt);
    -0162 fclose(fid);
    -0163 fprintf('Model-specific ComplexPortal database stored at %s\n',fullfile(params.path,'data','ComplexPortal.json'));
    -0164 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/change_model/getKcatAcrossIsozymes.html b/doc/src/geckomat/change_model/getKcatAcrossIsozymes.html deleted file mode 100644 index 319a64ad..00000000 --- a/doc/src/geckomat/change_model/getKcatAcrossIsozymes.html +++ /dev/null @@ -1,102 +0,0 @@ - - - - Description of getKcatAcrossIsozymes - - - - - - - - - -
    Home > src > geckomat > change_model > getKcatAcrossIsozymes.m
    - - - -

    getKcatAcrossIsozymes -

    - -

    PURPOSE ^

    -
    getKcatAcrossIsozymes
    - -

    SYNOPSIS ^

    -
    function model = getKcatAcrossIsozymes(model)
    - -

    DESCRIPTION ^

    -
     getKcatAcrossIsozymes
    -   For reactions without kcat value (0 in model.ec.kcat), isozymes are
    -   found (being based on the same reaction in the conventional GEM), that
    -   do have a kcat value assigned. The mean kcat value of these isozymes
    -   is then used to fill in model.ec.kcat.
    -
    - Input:
    -   model       an ecModel in full GECKO 3 format (with ecModel.ec structure),
    -               not GECKO light
    -
    - Output:
    -   model       an ecModel with kcat values assigned to isozymes in model.ec.kcat
    -
    - Usage: model = getKcatAcrossIsozymes(model);
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function model = getKcatAcrossIsozymes(model)
    -0002 % getKcatAcrossIsozymes
    -0003 %   For reactions without kcat value (0 in model.ec.kcat), isozymes are
    -0004 %   found (being based on the same reaction in the conventional GEM), that
    -0005 %   do have a kcat value assigned. The mean kcat value of these isozymes
    -0006 %   is then used to fill in model.ec.kcat.
    -0007 %
    -0008 % Input:
    -0009 %   model       an ecModel in full GECKO 3 format (with ecModel.ec structure),
    -0010 %               not GECKO light
    -0011 %
    -0012 % Output:
    -0013 %   model       an ecModel with kcat values assigned to isozymes in model.ec.kcat
    -0014 %
    -0015 % Usage: model = getKcatAcrossIsozymes(model);
    -0016 
    -0017 if model.ec.geckoLight
    -0018     error('Provided model is a GECKO light version, this function is not relevant for such models')
    -0019 end
    -0020 if all(model.ec.kcat==0)
    -0021     printOrange('WARNING: No kcat values are provided in model.ec.kcat, model remains unchanged.\n');
    -0022     return
    -0023 end
    -0024 
    -0025 noKcats     = model.ec.kcat==0;
    -0026 rxnIDs      = regexprep(model.ec.rxns,'_EXP_\d+','');
    -0027 noKcatID    = rxnIDs(noKcats);
    -0028 yesKcatID   = rxnIDs(~noKcats);
    -0029 yesKcatVal  = model.ec.kcat(~noKcats);
    -0030 
    -0031 noKcatVal   = cellfun(@(x) strcmp(x, yesKcatID), noKcatID, 'UniformOutput', false);
    -0032 noKcatVal   = cell2mat(cellfun(@(x) mean(yesKcatVal(x)), noKcatVal, 'UniformOutput', false));
    -0033 
    -0034 newKcat     = find(~isnan(noKcatVal));
    -0035 newKcatIdx  = find(noKcats);
    -0036 newKcatIdx  = newKcatIdx(newKcat);
    -0037 newKcat     = noKcatVal(newKcat);
    -0038 
    -0039 model.ec.kcat(newKcatIdx) = newKcat;
    -0040 model.ec.source(newKcatIdx) = {'isozymes'};
    -0041 end
    -0042
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/change_model/getReactionsFromEnzyme.html b/doc/src/geckomat/change_model/getReactionsFromEnzyme.html deleted file mode 100644 index 05f2a275..00000000 --- a/doc/src/geckomat/change_model/getReactionsFromEnzyme.html +++ /dev/null @@ -1,89 +0,0 @@ - - - - Description of getReactionsFromEnzyme - - - - - - - - - -
    Home > src > geckomat > change_model > getReactionsFromEnzyme.m
    - - - -

    getReactionsFromEnzyme -

    - -

    PURPOSE ^

    -
    getReactionsFromEnzyme
    - -

    SYNOPSIS ^

    -
    function [rxns, kcat, idx, rxnNames, grRules] = getReactionsFromEnzyme(ecModel,proteinId)
    - -

    DESCRIPTION ^

    -
     getReactionsFromEnzyme
    -   Get all reactions that are annotated to a particular enzyme.
    -
    - Input:
    -   ecModel     an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   proteinId   protein identifier, matching ecModel.ec.enzymes.
    -
    - Output:
    -   rxns        reactions that are associated with this enzyme
    -   kcat        kcat values of the corresponding reactions
    -   idx         index of the reactions in ecModel.ec.rxns
    -   rxnNames    names of the reactions
    -   grRules     grRules of the reactions
    -
    - Usage: [rxns, kcat, idx, rxnNames, grRules] = getReactionsFromEnzyme(ecModel,proteinId)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function [rxns, kcat, idx, rxnNames, grRules] = getReactionsFromEnzyme(ecModel,proteinId)
    -0002 % getReactionsFromEnzyme
    -0003 %   Get all reactions that are annotated to a particular enzyme.
    -0004 %
    -0005 % Input:
    -0006 %   ecModel     an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0007 %   proteinId   protein identifier, matching ecModel.ec.enzymes.
    -0008 %
    -0009 % Output:
    -0010 %   rxns        reactions that are associated with this enzyme
    -0011 %   kcat        kcat values of the corresponding reactions
    -0012 %   idx         index of the reactions in ecModel.ec.rxns
    -0013 %   rxnNames    names of the reactions
    -0014 %   grRules     grRules of the reactions
    -0015 %
    -0016 % Usage: [rxns, kcat, idx, rxnNames, grRules] = getReactionsFromEnzyme(ecModel,proteinId)
    -0017 
    -0018 protIdx     = find(strcmpi(ecModel.ec.enzymes,proteinId));
    -0019 ecRxnIdx    = find(ecModel.ec.rxnEnzMat(:,protIdx));
    -0020 rxns        = ecModel.ec.rxns(ecRxnIdx);
    -0021 kcat        = ecModel.ec.kcat(ecRxnIdx);
    -0022 
    -0023 idx         = ecRxnIdx;
    -0024 
    -0025 [~,rxnIdx]  = ismember(rxns,ecModel.rxns);
    -0026 rxnNames    = ecModel.rxnNames(rxnIdx);
    -0027 grRules     =  ecModel.grRules(rxnIdx);
    -0028 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/change_model/index.html b/doc/src/geckomat/change_model/index.html deleted file mode 100644 index 36e59847..00000000 --- a/doc/src/geckomat/change_model/index.html +++ /dev/null @@ -1,29 +0,0 @@ - - - - Index for Directory src\geckomat\change_model - - - - - - - - - - -
    < Master indexIndex for src\geckomat\change_model >
    - -

    Index for src\geckomat\change_model

    - -

    Matlab files in this directory:

    - -
     applyComplexDataapplyComplexData
     applyCustomKcatsapplyCustomKcats
     applyKcatConstraintsapplyKcatConstraints
     findMetSmilesfindMetSMILES
     getComplexDatagetComplexData
     getKcatAcrossIsozymesgetKcatAcrossIsozymes
     getReactionsFromEnzymegetReactionsFromEnzyme
     makeEcModelmakeEcModel
     setKcatForReactionssetKcatForReactions
     setProtPoolSizesetProtPoolSize
    - - - - -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/change_model/makeEcModel.html b/doc/src/geckomat/change_model/makeEcModel.html deleted file mode 100644 index 1b927758..00000000 --- a/doc/src/geckomat/change_model/makeEcModel.html +++ /dev/null @@ -1,544 +0,0 @@ - - - - Description of makeEcModel - - - - - - - - - -
    Home > src > geckomat > change_model > makeEcModel.m
    - - - -

    makeEcModel -

    - -

    PURPOSE ^

    -
    makeEcModel
    - -

    SYNOPSIS ^

    -
    function [model, noUniprot] = makeEcModel(model, geckoLight, modelAdapter)
    - -

    DESCRIPTION ^

    -
     makeEcModel
    -   Expands a conventional genome-scale model (in RAVEN format) with enzyme
    -   information and prepares the reactions for integration of enzyme usage
    -   coefficients. This function contains all the steps that need to be done
    -   to get a basic ecModel, without incorporating any kcat values or
    -   constraints yet. This function should only have to be run once for a
    -   model.
    -
    - Input:
    -   model        a model in RAVEN format
    -   geckoLight   true if a simplified GECKO light model should be generated.
    -                (Optional, default is false).
    -   modelAdapter a loaded model adapter (Optional, will otherwise use the
    -                default model adapter).
    -
    - Ouput:
    -   model        an ecModel in GECKO 3 format, with a model.ec structure where
    -                enzyme and kcat information are stored. Protein pseudo-
    -                metabolites and their draw reactions are added to the model,
    -                but their usage is not yet implemented (due to absent kcat
    -                values at this stage).
    -   noUniprot    genes for which no information could be found in the
    -                Uniprot database
    -
    - The function goes through the following steps:
    -   1.  Remove gene associations from pseudoreactions.
    -   2.  Invert irreversible backwards reactions.
    -   3.  Correct 'rev' vector to match lb and ub vectors.
    -   4.  Convert to irreversible model (splits reversible reactions).
    -   5.  [Skipped with geckoLight:] Expand model to split reactions with
    -       'OR' in grRules (each reaction is then catalyzed by one enzyme
    -       (complex).
    -   6.  Make empty model.ec structure, that will contain enzyme and kcat
    -       information. One entry per reaction, where isozymes have multiple
    -       entries. This model.ec structure will later be populated with kcat
    -       values. For geckoLight the structure is different, where each
    -       reaction can have multiple isozymes.
    -   7.  Add enzyme information fields to model.ec structure: MW, sequence.
    -   8.  Populate model.ec structure with information from each reaction.
    -   9.  [Skipped with geckoLight:] Add proteins as pseudometabolites.
    -   10. Add prot_pool pseudometabolite.
    -   11. [Skipped with geckoLight:] Add usage reactions for the protein
    -       pseudometabolites, replenishing from the protein pool (default, can
    -       be changed to consider proteomics data at later stage)
    -   12. Add protein pool reaction, without upper bound.
    -
    -   Note that while protein pseudometabolites, draw & pool reactions might
    -   be added to the model, the enzyme usage is not yet incorporated in each
    -   metabolic reaction, so enzymes will not be used. applyKcatConstraints
    -   incorporates protein pseudometabolites in reactions as enzyme usages by
    -   applying the specified kcats as constraints.
    -
    -The EC structure looks as follows
    - Attributes:
    -   geckoLight: 0 if full model, 1 if light
    -         rxns: reaction identifiers that correspond to model.rxns
    -         kcat: kcat values - not set here
    -       source: specifies where the kcats come from - not set here
    -        notes: notes that can be set by downstream functions - not set
    -               here
    -      eccodes: enzyme codes for each enzyme - not set here
    -        genes: the genes involved in the kcats - not necessarily the
    -               same as model.genes, since some genes may not be found in
    -               databases etc.
    -      enzymes: Uniprot protein identifiers for the genes
    -           mw: molecular weights of the enzymes
    -     sequence: sequence of the genes/enzymes
    -        concs: concentrations of the enzymes - not set here
    -    rxnEnzMat: matrix of enzymes and rxns
    -
    - The full model is split on all ORs in the GPRs, meaning that the
    - reactions will be duplicated for each isozyme. Only the rxns with genes
    - are added. The fields rxns, eccodes, kcat, source and notes will
    - therefore have one entry per reaction. The fields genes, enzymes, mw,
    - sequence and concs will have one entry per gene. The rxnEnzMat is a
    - matrix with reactions and genes, mapping which genes are connected to
    - which reaction (where isozymes have different reactions).
    -
    - The light model works a bit differently. The model has the same number of
    - rxns as the original model, but expanded since it is reversible + one the
    - extra prot maintenance rxn and one extra prot_pool rxn. However, the ec
    - fields rxns, eccodes, kcat, source and notes are duplicated for each
    - isozyme, sorted the same way as model.rxns. So, in model.ec.rxns, the
    - same reaction will appear several times after one another, one entry per
    - izozyme, with corresponding values for that isozyme. These fields
    - therefore have the same length as for the full model. The fields genes,
    - enzymes, mw, sequence and concs are the same here as in the full model.
    - The rxnEnzMat maps the model.ec.rxns entries to genes and is therefore of
    - the same size as for the full model.
    -
    - Usage:
    -   [model, noUniprot] = makeEcModel(model, geckoLight, modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 function [model, noUniprot] = makeEcModel(model, geckoLight, modelAdapter)
    -0002 % makeEcModel
    -0003 %   Expands a conventional genome-scale model (in RAVEN format) with enzyme
    -0004 %   information and prepares the reactions for integration of enzyme usage
    -0005 %   coefficients. This function contains all the steps that need to be done
    -0006 %   to get a basic ecModel, without incorporating any kcat values or
    -0007 %   constraints yet. This function should only have to be run once for a
    -0008 %   model.
    -0009 %
    -0010 % Input:
    -0011 %   model        a model in RAVEN format
    -0012 %   geckoLight   true if a simplified GECKO light model should be generated.
    -0013 %                (Optional, default is false).
    -0014 %   modelAdapter a loaded model adapter (Optional, will otherwise use the
    -0015 %                default model adapter).
    -0016 %
    -0017 % Ouput:
    -0018 %   model        an ecModel in GECKO 3 format, with a model.ec structure where
    -0019 %                enzyme and kcat information are stored. Protein pseudo-
    -0020 %                metabolites and their draw reactions are added to the model,
    -0021 %                but their usage is not yet implemented (due to absent kcat
    -0022 %                values at this stage).
    -0023 %   noUniprot    genes for which no information could be found in the
    -0024 %                Uniprot database
    -0025 %
    -0026 % The function goes through the following steps:
    -0027 %   1.  Remove gene associations from pseudoreactions.
    -0028 %   2.  Invert irreversible backwards reactions.
    -0029 %   3.  Correct 'rev' vector to match lb and ub vectors.
    -0030 %   4.  Convert to irreversible model (splits reversible reactions).
    -0031 %   5.  [Skipped with geckoLight:] Expand model to split reactions with
    -0032 %       'OR' in grRules (each reaction is then catalyzed by one enzyme
    -0033 %       (complex).
    -0034 %   6.  Make empty model.ec structure, that will contain enzyme and kcat
    -0035 %       information. One entry per reaction, where isozymes have multiple
    -0036 %       entries. This model.ec structure will later be populated with kcat
    -0037 %       values. For geckoLight the structure is different, where each
    -0038 %       reaction can have multiple isozymes.
    -0039 %   7.  Add enzyme information fields to model.ec structure: MW, sequence.
    -0040 %   8.  Populate model.ec structure with information from each reaction.
    -0041 %   9.  [Skipped with geckoLight:] Add proteins as pseudometabolites.
    -0042 %   10. Add prot_pool pseudometabolite.
    -0043 %   11. [Skipped with geckoLight:] Add usage reactions for the protein
    -0044 %       pseudometabolites, replenishing from the protein pool (default, can
    -0045 %       be changed to consider proteomics data at later stage)
    -0046 %   12. Add protein pool reaction, without upper bound.
    -0047 %
    -0048 %   Note that while protein pseudometabolites, draw & pool reactions might
    -0049 %   be added to the model, the enzyme usage is not yet incorporated in each
    -0050 %   metabolic reaction, so enzymes will not be used. applyKcatConstraints
    -0051 %   incorporates protein pseudometabolites in reactions as enzyme usages by
    -0052 %   applying the specified kcats as constraints.
    -0053 %
    -0054 %The EC structure looks as follows
    -0055 % Attributes:
    -0056 %   geckoLight: 0 if full model, 1 if light
    -0057 %         rxns: reaction identifiers that correspond to model.rxns
    -0058 %         kcat: kcat values - not set here
    -0059 %       source: specifies where the kcats come from - not set here
    -0060 %        notes: notes that can be set by downstream functions - not set
    -0061 %               here
    -0062 %      eccodes: enzyme codes for each enzyme - not set here
    -0063 %        genes: the genes involved in the kcats - not necessarily the
    -0064 %               same as model.genes, since some genes may not be found in
    -0065 %               databases etc.
    -0066 %      enzymes: Uniprot protein identifiers for the genes
    -0067 %           mw: molecular weights of the enzymes
    -0068 %     sequence: sequence of the genes/enzymes
    -0069 %        concs: concentrations of the enzymes - not set here
    -0070 %    rxnEnzMat: matrix of enzymes and rxns
    -0071 %
    -0072 % The full model is split on all ORs in the GPRs, meaning that the
    -0073 % reactions will be duplicated for each isozyme. Only the rxns with genes
    -0074 % are added. The fields rxns, eccodes, kcat, source and notes will
    -0075 % therefore have one entry per reaction. The fields genes, enzymes, mw,
    -0076 % sequence and concs will have one entry per gene. The rxnEnzMat is a
    -0077 % matrix with reactions and genes, mapping which genes are connected to
    -0078 % which reaction (where isozymes have different reactions).
    -0079 %
    -0080 % The light model works a bit differently. The model has the same number of
    -0081 % rxns as the original model, but expanded since it is reversible + one the
    -0082 % extra prot maintenance rxn and one extra prot_pool rxn. However, the ec
    -0083 % fields rxns, eccodes, kcat, source and notes are duplicated for each
    -0084 % isozyme, sorted the same way as model.rxns. So, in model.ec.rxns, the
    -0085 % same reaction will appear several times after one another, one entry per
    -0086 % izozyme, with corresponding values for that isozyme. These fields
    -0087 % therefore have the same length as for the full model. The fields genes,
    -0088 % enzymes, mw, sequence and concs are the same here as in the full model.
    -0089 % The rxnEnzMat maps the model.ec.rxns entries to genes and is therefore of
    -0090 % the same size as for the full model.
    -0091 %
    -0092 % Usage:
    -0093 %   [model, noUniprot] = makeEcModel(model, geckoLight, modelAdapter)
    -0094 
    -0095 if nargin<2
    -0096     geckoLight=false;
    -0097 elseif ~islogical(geckoLight) && ~(geckoLight == 0) && ~(geckoLight == 1)
    -0098     error('geckoLight should be either true or false')
    -0099 end
    -0100 
    -0101 if nargin < 3 || isempty(modelAdapter)
    -0102     modelAdapter = ModelAdapterManager.getDefault();
    -0103     if isempty(modelAdapter)
    -0104         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0105     end
    -0106 end
    -0107 params = modelAdapter.getParameters();
    -0108 compartmentID = strcmp(model.compNames,params.enzyme_comp);
    -0109 if ~any(compartmentID)
    -0110     error(['Compartment ' params.enzyme_comp ' (specified in params.enzyme_comp) '...
    -0111            'cannot be found in model.compNames'])
    -0112 end
    -0113 compartmentID = model.comps(compartmentID);
    -0114 
    -0115 if geckoLight
    -0116     ec.geckoLight=true;
    -0117 else
    -0118     ec.geckoLight=false;
    -0119 end
    -0120 
    -0121 %Check if model is in RAVEN format
    -0122 if any(isfield(model,{'rules','modelID'}))
    -0123     error(['The model is likely loaded using COBRA Toolbox readCbModel(). Instead, use ' ...
    -0124            'RAVEN Toolbox importModel(). Alternatively, you can also convert the ', ...
    -0125            'model in MATLAB using ravenCobraWrapper().'])
    -0126 end
    -0127 
    -0128 %Check for conflicting reaction and metabolite identifiers
    -0129 conflictId = startsWith(model.mets,'prot_');
    -0130 if any(conflictId)
    -0131     error('The identifiers in model.mets are not allowed to start with ''prot_''.')
    -0132 end
    -0133 conflictId = startsWith(model.rxns,{'usage_prot_','prot_pool'}) | ...
    -0134              endsWith(model.rxns,'_REV') | ...
    -0135              ~cellfun(@isempty,regexp(model.rxns,'_EXP_\d+$'));
    -0136 if any(conflictId)
    -0137     error(['The identifiers in model.rxns are not allowed to start with ''usage_prot'' ' ...
    -0138            'or ''prot_pool'', or end with ''_REV'' or ''_EXP_[digit]''.'])
    -0139 end
    -0140 
    -0141 uniprotDB = loadDatabases('both', modelAdapter);
    -0142 uniprotDB = uniprotDB.uniprot;
    -0143 
    -0144 %1: Remove gene rules from pseudoreactions (if any):
    -0145 if exist(fullfile(params.path,'data','pseudoRxns.tsv'),'file')
    -0146     fID        = fopen(fullfile(params.path,'data','pseudoRxns.tsv'));
    -0147     fileData   = textscan(fID,'%s %s','delimiter','\t');
    -0148     fclose(fID);
    -0149     pseudoRxns = fileData{1};
    -0150     pseudoRxns = ismember(model.rxns,pseudoRxns);
    -0151 else
    -0152     pseudoRxns = false(numel(model.rxns),1);
    -0153 end
    -0154 pseudoRxns = find(pseudoRxns | contains(model.rxnNames,'pseudoreaction'));
    -0155 model.grRules(pseudoRxns)       = {''};
    -0156 model.rxnGeneMat(pseudoRxns,:)  = zeros(numel(pseudoRxns), numel(model.genes));
    -0157 
    -0158 %2: Swap direction of reactions that are defined to only carry negative flux
    -0159 to_swap=model.lb < 0 & model.ub == 0;
    -0160 model.S(:,to_swap)=-model.S(:,to_swap);
    -0161 model.ub(to_swap)=-model.lb(to_swap);
    -0162 model.lb(to_swap)=0;
    -0163 
    -0164 %3: Correct rev vector: true if LB < 0 & UB > 0, or it is an exchange reaction:
    -0165 model.rev = false(size(model.rxns));
    -0166 for i = 1:length(model.rxns)
    -0167     if (model.lb(i) < 0 && model.ub(i) > 0) || sum(model.S(:,i) ~= 0) == 1
    -0168         model.rev(i) = true;
    -0169     end
    -0170 end
    -0171 
    -0172 %4: Make irreversible model (appends _REV to reaction IDs to indicate reverse
    -0173 %reactions)
    -0174 [~,exchRxns] = getExchangeRxns(model);
    -0175 nonExchRxns = model.rxns;
    -0176 nonExchRxns(exchRxns) = [];
    -0177 model=convertToIrrev(model, nonExchRxns);
    -0178 
    -0179 %5: Expand model, to separate isozymes (appends _EXP_* to reaction IDs to
    -0180 %indicate duplication)
    -0181 if ~geckoLight
    -0182     model=expandModel(model);
    -0183 end
    -0184 % Sort reactions, so that reversible and isozymic reactions are kept near
    -0185 if ~geckoLight
    -0186     model=sortIdentifiers(model);
    -0187 end
    -0188 
    -0189 %6: Make ec-extension structure, one for gene-associated reaction.
    -0190 %   The structure is different for light and full models
    -0191 rxnWithGene  = find(sum(model.rxnGeneMat,2));
    -0192 if ~geckoLight
    -0193     ec.rxns      = model.rxns(rxnWithGene);
    -0194     emptyCell    = cell(numel(rxnWithGene),1);
    -0195     emptyCell(:) = {''};
    -0196     emptyVect    = zeros(numel(rxnWithGene),1);
    -0197     
    -0198     ec.kcat      = emptyVect;
    -0199     ec.source    = emptyCell; % Strings, like 'dlkcat', 'manual', 'brenda', etc.
    -0200     ec.notes     = emptyCell; % Additional comments
    -0201     ec.eccodes   = emptyCell;
    -0202     ec.concs     = emptyVect;
    -0203 else
    -0204     %Different strategy for GECKO light: Each reaction can exist multiple times in
    -0205     %ec.rxns and similar fields - one time per isozyme. The number of copies is
    -0206     %the number of ORs in the GPR + 1
    -0207     numOrs = count(model.grRules(rxnWithGene), ' or ');
    -0208     cpys = numOrs + 1;
    -0209     prevNumRxns = length(numOrs);
    -0210     cpyIndices = repelem(rxnWithGene, cpys).'; %.' only matter when number of rxns is 1
    -0211     %loop through and add a prefix with an isozyme index to the rxns
    -0212     %we just give a fixed-length number as prefix, and assume that 999 is enough
    -0213     tmpRxns = model.rxns(cpyIndices); %now they have no prefix
    -0214     newRxns = tmpRxns;
    -0215     
    -0216     %add the prefix
    -0217     nextIndex = 1;
    -0218     for i = 1:numel(model.rxns)
    -0219         localRxnIndex = 1;
    -0220         if nextIndex <= length(tmpRxns) && strcmp(model.rxns(i), tmpRxns(nextIndex))
    -0221             while true
    -0222                 tmp = compose('%03d_',localRxnIndex);
    -0223                 newRxns{nextIndex} = [tmp{1} tmpRxns{nextIndex}];
    -0224                 localRxnIndex = localRxnIndex + 1;
    -0225                 if (localRxnIndex >= 1000)
    -0226                     error('Increase index size to 10000 - error in the code.'); %this should never happen, we don't have > 999 isozymes
    -0227                 end
    -0228                 nextIndex = nextIndex + 1;
    -0229                 if  nextIndex > length(tmpRxns) || ~strcmp(model.rxns(i), tmpRxns(nextIndex))
    -0230                     break;
    -0231                 end
    -0232             end
    -0233         end
    -0234     end
    -0235 
    -0236     ec.rxns      = newRxns;
    -0237     
    -0238     emptyCell    = cell(numel(ec.rxns),1);
    -0239     emptyCell(:) = {''};
    -0240     emptyVect    = zeros(numel(ec.rxns),1);
    -0241 
    -0242     ec.kcat      = emptyVect;
    -0243     ec.source    = emptyCell; % Strings, like 'dlkcat', 'manual', 'brenda', etc.
    -0244     ec.notes     = emptyCell; % Additional comments
    -0245     ec.eccodes   = emptyCell;
    -0246     ec.concs     = emptyVect;
    -0247 end
    -0248     
    -0249 %7: Gather enzyme information via UniprotDB
    -0250 uniprotCompatibleGenes = modelAdapter.getUniprotCompatibleGenes(model.genes);
    -0251 [Lia,Locb] = ismember(uniprotCompatibleGenes,uniprotDB.genes);
    -0252 
    -0253 uniprot = modelAdapter.getUniprotIDsFromTable(uniprotCompatibleGenes);
    -0254 if ~isequal(uniprot,uniprotCompatibleGenes)
    -0255     uniprot(cellfun(@isempty,uniprot)) = {''};
    -0256     [Lia,Locb] = ismember(uniprot,uniprotDB.ID);
    -0257 end
    -0258 noUniprot  = uniprotCompatibleGenes(~Lia);
    -0259 if all(~Lia)
    -0260     error('None of the proteins in uniprot.tsv match the genes in the model. Changes to the obj.params.uniprot parameters, or a data/uniprotConversion.tsv file are likely required.')
    -0261 elseif ~isempty(noUniprot)
    -0262     printOrange(['WARNING: The ' num2str(numel(noUniprot)) ' gene(s) reported '...
    -0263         'in "noUniprot" cannot be found in data/uniprot.tsv, these will ' ...
    -0264         'not be enzyme-constrained. If you intend to use different Uniprot '...
    -0265         'data (e.g. from a different proteome, make sure you first delete '...
    -0266         'the existing data/uniprot.tsv file.\n']);
    -0267 end
    -0268 ec.genes        = model.genes(Lia); %Will often be duplicate of model.genes, but is done here to prevent issues when it is not.
    -0269 ec.enzymes      = uniprotDB.ID(Locb(Lia));
    -0270 ec.mw           = uniprotDB.MW(Locb(Lia));
    -0271 ec.sequence     = uniprotDB.seq(Locb(Lia));
    -0272 %Additional info
    -0273 ec.concs        = nan(numel(ec.genes),1); % To be filled with proteomics data when available
    -0274 
    -0275 %8: Only parse rxns associated to genes
    -0276 if ~geckoLight
    -0277     ec.rxnEnzMat = zeros(numel(rxnWithGene),numel(ec.genes)); % Non-zeros will indicate the number of subunits
    -0278     for r=1:numel(rxnWithGene)
    -0279         rxnGenes   = model.genes(find(model.rxnGeneMat(rxnWithGene(r),:)));
    -0280         [~,locEnz] = ismember(rxnGenes,ec.genes); % Could also parse directly from rxnGeneMat, but some genes might be missing from Uniprot DB
    -0281         if locEnz ~= 0
    -0282             ec.rxnEnzMat(r,locEnz) = 1; %Assume 1 copy per subunit or enzyme, can be modified later
    -0283         end
    -0284     end
    -0285 else
    -0286     %For light models, we need to split up all GPRs
    -0287     ec.rxnEnzMat = zeros(numel(ec.rxns),numel(ec.genes)); % Non-zeros will indicate the number of subunits
    -0288     nextIndex = 1;
    -0289     %For full model generation, the GPRs are controlled in expandModel, but
    -0290     %here we need to make an explicit format check
    -0291     indexes2check = findPotentialErrors(model.grRules,model);
    -0292     if ~isempty(indexes2check) 
    -0293         printOrange('Run standardizeGrRules(model) for a more detailed warning.\n');
    -0294         printOrange('For Human-GEM, these reactions can be corrected using simplifyGrRules.\n');
    -0295     end
    -0296     
    -0297     for i=1:prevNumRxns
    -0298         %ind is the index in the model, not to confuse with the index in the ec struct (i),
    -0299         %which only contains reactions with GPRs.
    -0300         ind = rxnWithGene(i); 
    -0301         %Get rid of all '(' and ')' since I'm not looking at complex stuff
    -0302         %anyways
    -0303         geneString=model.grRules{ind};
    -0304         geneString=strrep(geneString,'(','');
    -0305         geneString=strrep(geneString,')','');
    -0306         geneString=strrep(geneString,' or ',';');
    -0307         
    -0308         if (numOrs(i) == 0)
    -0309             geneNames = {geneString};
    -0310         else
    -0311             %Split the string into gene names
    -0312             geneNames=regexp(geneString,';','split');
    -0313         end
    -0314         
    -0315         %Now loop through the isozymes and set the rxnGeneMat
    -0316         for j = 1:length(geneNames)
    -0317             %Find the gene in the gene list If ' and ' relationship, first
    -0318             %split the genes
    -0319             fnd = strfind(geneNames{j},' and ');
    -0320             if ~isempty(fnd)
    -0321                 andGenes=regexp(geneNames{j},' and ','split');
    -0322                 ec.rxnEnzMat(nextIndex,ismember(ec.genes,andGenes)) = 1; %should be subunit stoichoimetry
    -0323             else
    -0324                 ec.rxnEnzMat(nextIndex,ismember(ec.genes,geneNames(j)))=1;%should be subunit stoichoimetry
    -0325             end
    -0326             nextIndex = nextIndex + 1;
    -0327         end
    -0328     end
    -0329 end
    -0330 
    -0331 %9: Add proteins as pseudometabolites
    -0332 if ~geckoLight
    -0333     [proteinMets.mets, uniprotSortId] = unique(ec.enzymes);
    -0334     proteinMets.mets         = strcat('prot_',proteinMets.mets);
    -0335     proteinMets.metNames     = proteinMets.mets;
    -0336     proteinMets.compartments = compartmentID;
    -0337     if isfield(model,'metMiriams')
    -0338         proteinMets.metMiriams   = repmat({struct('name',{{'sbo'}},'value',{{'SBO:0000252'}})},numel(proteinMets.mets),1);
    -0339     end
    -0340     if isfield(model,'metCharges')
    -0341         proteinMets.metCharges   = zeros(numel(proteinMets.mets),1);
    -0342     end
    -0343     proteinMets.metNotes     = repmat({'Enzyme-usage pseudometabolite'},numel(proteinMets.mets),1);
    -0344     model = addMets(model,proteinMets);
    -0345 end
    -0346 
    -0347 %10: Add protein pool pseudometabolite
    -0348 pool.mets         = 'prot_pool';
    -0349 pool.metNames     = pool.mets;
    -0350 pool.compartments = compartmentID;
    -0351 pool.metNotes     = 'Enzyme-usage protein pool';
    -0352 model = addMets(model,pool);
    -0353 
    -0354 %11: Add protein usage reactions.
    -0355 if ~geckoLight
    -0356     usageRxns.rxns            = strcat('usage_',proteinMets.mets);
    -0357     usageRxns.rxnNames        = usageRxns.rxns;
    -0358     usageRxns.mets            = cell(numel(usageRxns.rxns),1);
    -0359     usageRxns.stoichCoeffs    = cell(numel(usageRxns.rxns),1);
    -0360     for i=1:numel(usageRxns.mets)
    -0361         usageRxns.mets{i}         = {proteinMets.mets{i}, 'prot_pool'};
    -0362         usageRxns.stoichCoeffs{i} = [-1,1];
    -0363     end
    -0364     usageRxns.lb              = zeros(numel(usageRxns.rxns),1) - 1000;
    -0365     usageRxns.ub              = zeros(numel(usageRxns.rxns),1);
    -0366     usageRxns.rev             = ones(numel(usageRxns.rxns),1);
    -0367     usageRxns.grRules         = ec.genes(uniprotSortId);
    -0368     model = addRxns(model,usageRxns);
    -0369 end
    -0370 
    -0371 %12: Add protein pool reaction (with open UB)
    -0372 poolRxn.rxns            = 'prot_pool_exchange';
    -0373 poolRxn.rxnNames        = poolRxn.rxns;
    -0374 poolRxn.mets            = {'prot_pool'};
    -0375 poolRxn.stoichCoeffs    = {-1};
    -0376 poolRxn.lb              = -1000;
    -0377 poolRxn.ub              = 0;
    -0378 poolRxn.rev             = 1;
    -0379 model = addRxns(model,poolRxn);
    -0380 
    -0381 model.ec=ec;
    -0382 end
    -0383 
    -0384 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0385 %Function that gets the model field grRules and returns the indexes of the
    -0386 %rules in which the pattern ") and (" is present.
    -0387 %Copied from standardizeGrRules
    -0388 % TODO: Make this an accessible function in a separate file in RAVEN and remove this
    -0389 %implementation.
    -0390 function indexes2check = findPotentialErrors(grRules,model)
    -0391 indxs_l       = find(~cellfun(@isempty,strfind(grRules,') and (')));
    -0392 indxs_l_L     = find(~cellfun(@isempty,strfind(grRules,') and')));
    -0393 indxs_l_R     = find(~cellfun(@isempty,strfind(grRules,'and (')));
    -0394 indexes2check = vertcat(indxs_l,indxs_l_L,indxs_l_R);
    -0395 indexes2check = unique(indexes2check);
    -0396 
    -0397 if ~isempty(indexes2check)
    -0398     textToPrint = 'WARNING: Potentially problematic ") AND (" in the grRules for reaction(s):\n';
    -0399     for i=1:numel(indexes2check)
    -0400         textToPrint=[textToPrint '\t' model.rxns{indexes2check(i)} '\n'];
    -0401     end
    -0402     printOrange(textToPrint);
    -0403 end
    -0404 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/change_model/setKcatForReactions.html b/doc/src/geckomat/change_model/setKcatForReactions.html deleted file mode 100644 index cdcb9ea1..00000000 --- a/doc/src/geckomat/change_model/setKcatForReactions.html +++ /dev/null @@ -1,120 +0,0 @@ - - - - Description of setKcatForReactions - - - - - - - - - -
    Home > src > geckomat > change_model > setKcatForReactions.m
    - - - -

    setKcatForReactions -

    - -

    PURPOSE ^

    -
    setKcatForReactions
    - -

    SYNOPSIS ^

    -
    function ecModel = setKcatForReactions(ecModel,rxnIds,kcat)
    - -

    DESCRIPTION ^

    -
     setKcatForReactions
    -   Change the kcat value in ecModel.ec.kcat for selected reactions.
    -   applyKcatConstraints needs to be run afterwards to transfer the kcat
    -   values into the S-matrix.
    -
    - Input:
    -   ecModel     an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   rxnIds      reaction identifier matching ecModel.ec.rxns. If the _EXP_.
    -               suffix is not included, and there are multiple expanded
    -               (isozymic) reactions, then all off those will have their
    -               kcat changed. If rxnIds includes a _EXP_ suffix, then only
    -               that specific reaction will have its kcat changed. If
    -               multiple rxnIds are provided as a cell array, then the
    -               above applies to each rxnIds individual.
    -   kcat        the new kcat value
    -
    - Output:
    -   ecModel     ecModel where selected kcat values in ecModel.ec.kcat are
    -               changed, but not yet applied to the S-matrix (will require
    -               to run applyKcatConstraints). ecModel.ec.source for the
    -               changed reactions will read 'from setKcatForReactions'
    -
    - Usage: ecModel = setKcatForReactions(ecModel,rxnIds,kcat)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function ecModel = setKcatForReactions(ecModel,rxnIds,kcat)
    -0002 % setKcatForReactions
    -0003 %   Change the kcat value in ecModel.ec.kcat for selected reactions.
    -0004 %   applyKcatConstraints needs to be run afterwards to transfer the kcat
    -0005 %   values into the S-matrix.
    -0006 %
    -0007 % Input:
    -0008 %   ecModel     an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0009 %   rxnIds      reaction identifier matching ecModel.ec.rxns. If the _EXP_.
    -0010 %               suffix is not included, and there are multiple expanded
    -0011 %               (isozymic) reactions, then all off those will have their
    -0012 %               kcat changed. If rxnIds includes a _EXP_ suffix, then only
    -0013 %               that specific reaction will have its kcat changed. If
    -0014 %               multiple rxnIds are provided as a cell array, then the
    -0015 %               above applies to each rxnIds individual.
    -0016 %   kcat        the new kcat value
    -0017 %
    -0018 % Output:
    -0019 %   ecModel     ecModel where selected kcat values in ecModel.ec.kcat are
    -0020 %               changed, but not yet applied to the S-matrix (will require
    -0021 %               to run applyKcatConstraints). ecModel.ec.source for the
    -0022 %               changed reactions will read 'from setKcatForReactions'
    -0023 %
    -0024 % Usage: ecModel = setKcatForReactions(ecModel,rxnIds,kcat)
    -0025 rxnIds = convertCharArray(rxnIds);
    -0026 
    -0027 hasExp       = ~cellfun(@isempty,regexp(rxnIds,'_EXP_\d+$'));
    -0028 nonExpRxns   = regexprep(ecModel.ec.rxns,'_EXP_\d+$','');
    -0029 rxnsToChange = [];
    -0030 for i=1:numel(hasExp)
    -0031     if hasExp(i) == 1
    -0032         rxnsToChange = [rxnsToChange; find(strcmpi(ecModel.ec.rxns,rxnIds{i}))];
    -0033     else
    -0034         nonExpRxn    = regexprep(rxnIds(i),'_EXP_\d+$','');
    -0035         rxnsToChange = [rxnsToChange; find(strcmpi(nonExpRxns,nonExpRxn))];
    -0036     end
    -0037 end
    -0038 if isscalar(rxnsToChange)
    -0039     if length(kcat) ~= 1
    -0040         error('Found one reaction whose kcat should change, you should provide one kcat value only.')
    -0041     end
    -0042 else
    -0043     if isscalar(kcat)
    -0044         % Is fine, all reactions get the same kcat
    -0045     elseif length(kcat) ~= length(rxnsToChange)
    -0046         error('Found %d reactions whose kcat should change, the new kcat should be either a single value, or a vector of length %d.', length(rxnsToChange), length(rxnsToChange))
    -0047     end
    -0048 end
    -0049 ecModel.ec.kcat(rxnsToChange)   = kcat;
    -0050 ecModel.ec.source(rxnsToChange) = {'setKcatForReactions'};
    -0051 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/change_model/setProtPoolSize.html b/doc/src/geckomat/change_model/setProtPoolSize.html deleted file mode 100644 index 853fb50b..00000000 --- a/doc/src/geckomat/change_model/setProtPoolSize.html +++ /dev/null @@ -1,114 +0,0 @@ - - - - Description of setProtPoolSize - - - - - - - - - -
    Home > src > geckomat > change_model > setProtPoolSize.m
    - - - -

    setProtPoolSize -

    - -

    PURPOSE ^

    -
    setProtPoolSize
    - -

    SYNOPSIS ^

    -
    function model = setProtPoolSize(model, Ptot, f, sigma, modelAdapter)
    - -

    DESCRIPTION ^

    -
     setProtPoolSize
    -   Sets the limit of the total protein usage in the model.
    -
    - Input:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   Ptot            Total cellular protein content in g/gDCW. If not
    -                   specified, the value will be read from the model
    -                   adapter. If not specified in model adapter, 0.5 g/gDCW
    -                   is assumed.
    -   f               Estimated fraction of enzymes in the model. If not
    -                   specified, the value will be read from the model
    -                   adapter. If not specified in model adapter, 0.5 is
    -                   assumed.
    -   sigma           Estimated saturation factor. If not specified, the
    -                   value will be read from the model adapter. If not
    -                   specified in model adapter, 0.5 is assumed.
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -                   default model adapter).
    -
    - Output:
    -   model           ecModel with protein pool constraint set
    -
    - Usage: model = setProtPoolSize(model, Ptot, f, sigma, modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function model = setProtPoolSize(model, Ptot, f, sigma, modelAdapter)
    -0002 % setProtPoolSize
    -0003 %   Sets the limit of the total protein usage in the model.
    -0004 %
    -0005 % Input:
    -0006 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0007 %   Ptot            Total cellular protein content in g/gDCW. If not
    -0008 %                   specified, the value will be read from the model
    -0009 %                   adapter. If not specified in model adapter, 0.5 g/gDCW
    -0010 %                   is assumed.
    -0011 %   f               Estimated fraction of enzymes in the model. If not
    -0012 %                   specified, the value will be read from the model
    -0013 %                   adapter. If not specified in model adapter, 0.5 is
    -0014 %                   assumed.
    -0015 %   sigma           Estimated saturation factor. If not specified, the
    -0016 %                   value will be read from the model adapter. If not
    -0017 %                   specified in model adapter, 0.5 is assumed.
    -0018 %   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -0019 %                   default model adapter).
    -0020 %
    -0021 % Output:
    -0022 %   model           ecModel with protein pool constraint set
    -0023 %
    -0024 % Usage: model = setProtPoolSize(model, Ptot, f, sigma, modelAdapter)
    -0025 
    -0026 if nargin < 5 || isempty(modelAdapter)
    -0027     modelAdapter = ModelAdapterManager.getDefault();
    -0028     if isempty(modelAdapter) && (nargin<2 || isempty(Ptot) || isempty(f) || isempty(sigma))
    -0029         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0030     end
    -0031 end
    -0032 
    -0033 if nargin<4 || isempty(sigma)
    -0034     sigma = modelAdapter.getParameters().sigma;
    -0035 end
    -0036 if nargin<3 || isempty(f)
    -0037     f = modelAdapter.getParameters().f;
    -0038 end
    -0039 if nargin<2 || isempty(Ptot)
    -0040     Ptot = modelAdapter.getParameters().Ptot;
    -0041 end
    -0042 
    -0043 model.lb(strcmp(model.rxns, 'prot_pool_exchange')) = -(Ptot*f*sigma*1000);
    -0044 end
    -0045
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/gather_kcats/fuzzyKcatMatching.html b/doc/src/geckomat/gather_kcats/fuzzyKcatMatching.html deleted file mode 100644 index 86e8db83..00000000 --- a/doc/src/geckomat/gather_kcats/fuzzyKcatMatching.html +++ /dev/null @@ -1,611 +0,0 @@ - - - - Description of fuzzyKcatMatching - - - - - - - - - -
    Home > src > geckomat > gather_kcats > fuzzyKcatMatching.m
    - - - -

    fuzzyKcatMatching -

    - -

    PURPOSE ^

    -
    fuzzyKcatMatching
    - -

    SYNOPSIS ^

    -
    function kcatList = fuzzyKcatMatching(model, ecRxns, modelAdapter, forceWClvl)
    - -

    DESCRIPTION ^

    -
     fuzzyKcatMatching
    -   Matchs the model EC numbers and substrates to the BRENDA database, to
    -   return the corresponding kcats for each reaction. If no exact match is
    -   found, less specific kcat values are found from (a) evolutionary
    -   closely related organism; (b) different substrate; (c) calculated from
    -   specific activities; (d) wildcards in the EC number. The model organism
    -   is provided in the model adapter as obj.params.org_name, and
    -   evolutionary distance to other organisms is determined via KEGG
    -   phylogeny. If an organism name occurs multiple times in KEGG, the first
    -   instance will be used when determining evolutionary distance.
    -
    - Input:
    -   model        an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   ecRxns       for which reactions (from model.ec.rxns) kcat values should
    -                be found, provided as logical vector with same length as
    -                model.ec.rxns. (Opt, default is all reactions)
    -   modelAdapter a loaded model adapter (Optional, will otherwise use the
    -                default model adapter).
    -   forceWClvl   force a minimum wildcard level (Optional, default 0). 
    -
    - Output:
    -   kcatList    structure array with list of BRENDA derived kcat values,
    -               with separate entries for each kcat value
    -               source      'brenda'           
    -               rxns        reaction identifiers
    -               substrate   substrate names
    -               kcat        proposed kcat value in /sec
    -               eccodes     as used to query BRENDA
    -               wildCardLvl which level of EC wild-card was necessary to
    -                           find a match
    -                           0: w.x.y.z
    -                           1: w.x.y.-
    -                           2: w.x.-.-
    -                           3: w.-.-.-
    -               origin      which level of specificity was necessary to
    -                           find a match
    -                           1: correct organism, correct substrate, kcat
    -                           2: any organism, correct substrate, kcat
    -                           3: correct organism, any substrate, kcat
    -                           4: any organism, any substrate, kcat
    -                           5: correct organism, specific activity
    -                           6: any organism, specific activity
    -
    -   Note: If a wildcard is used, origin levels 1 and 2 are ignored. The
    -   last digits in the E.C. number indicate the substrate specificity, so
    -   if this should be ignored, then correct substrate matches should not be
    -   prioritized.
    -
    - Usage:
    -   kcatList = fuzzyKcatMatching(model, ecRxns, modelAdapter, forceWClvl)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 function kcatList = fuzzyKcatMatching(model, ecRxns, modelAdapter, forceWClvl)
    -0002 % fuzzyKcatMatching
    -0003 %   Matchs the model EC numbers and substrates to the BRENDA database, to
    -0004 %   return the corresponding kcats for each reaction. If no exact match is
    -0005 %   found, less specific kcat values are found from (a) evolutionary
    -0006 %   closely related organism; (b) different substrate; (c) calculated from
    -0007 %   specific activities; (d) wildcards in the EC number. The model organism
    -0008 %   is provided in the model adapter as obj.params.org_name, and
    -0009 %   evolutionary distance to other organisms is determined via KEGG
    -0010 %   phylogeny. If an organism name occurs multiple times in KEGG, the first
    -0011 %   instance will be used when determining evolutionary distance.
    -0012 %
    -0013 % Input:
    -0014 %   model        an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0015 %   ecRxns       for which reactions (from model.ec.rxns) kcat values should
    -0016 %                be found, provided as logical vector with same length as
    -0017 %                model.ec.rxns. (Opt, default is all reactions)
    -0018 %   modelAdapter a loaded model adapter (Optional, will otherwise use the
    -0019 %                default model adapter).
    -0020 %   forceWClvl   force a minimum wildcard level (Optional, default 0).
    -0021 %
    -0022 % Output:
    -0023 %   kcatList    structure array with list of BRENDA derived kcat values,
    -0024 %               with separate entries for each kcat value
    -0025 %               source      'brenda'
    -0026 %               rxns        reaction identifiers
    -0027 %               substrate   substrate names
    -0028 %               kcat        proposed kcat value in /sec
    -0029 %               eccodes     as used to query BRENDA
    -0030 %               wildCardLvl which level of EC wild-card was necessary to
    -0031 %                           find a match
    -0032 %                           0: w.x.y.z
    -0033 %                           1: w.x.y.-
    -0034 %                           2: w.x.-.-
    -0035 %                           3: w.-.-.-
    -0036 %               origin      which level of specificity was necessary to
    -0037 %                           find a match
    -0038 %                           1: correct organism, correct substrate, kcat
    -0039 %                           2: any organism, correct substrate, kcat
    -0040 %                           3: correct organism, any substrate, kcat
    -0041 %                           4: any organism, any substrate, kcat
    -0042 %                           5: correct organism, specific activity
    -0043 %                           6: any organism, specific activity
    -0044 %
    -0045 %   Note: If a wildcard is used, origin levels 1 and 2 are ignored. The
    -0046 %   last digits in the E.C. number indicate the substrate specificity, so
    -0047 %   if this should be ignored, then correct substrate matches should not be
    -0048 %   prioritized.
    -0049 %
    -0050 % Usage:
    -0051 %   kcatList = fuzzyKcatMatching(model, ecRxns, modelAdapter, forceWClvl)
    -0052 
    -0053 if nargin<2 || isempty(ecRxns)
    -0054     ecRxns = true(numel(model.ec.rxns),1);
    -0055 elseif isnumeric(ecRxns)
    -0056     ecRxnsVec = false(numel(model.ec.rxns),1);
    -0057     ecRxnsVec(ecRxns) = true;
    -0058     ecRxns = ecRxnsVec;
    -0059 end
    -0060 ecRxns=find(ecRxns); % Get indices instead of logical
    -0061 
    -0062 if nargin < 3 || isempty(modelAdapter)
    -0063     modelAdapter = ModelAdapterManager.getDefault();
    -0064     if isempty(modelAdapter)
    -0065         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0066     end
    -0067 end
    -0068 params = modelAdapter.params;
    -0069 
    -0070 if nargin < 4 || isempty(forceWClvl)
    -0071     forceWClvl = 0;
    -0072 end
    -0073 
    -0074 if ~isfield(model.ec,'eccodes')
    -0075     error('No EC codes defined in model.ec.eccodes. First run getECfromGEM() and/or getECfromDatabase().')
    -0076 end
    -0077 eccodes      = model.ec.eccodes(ecRxns);
    -0078 substrates   = cell(numel(ecRxns),1);
    -0079 substrCoeffs = cell(numel(ecRxns),1);
    -0080 
    -0081 %Need to remove the prefix of GECKO light rxn names in the ec structure
    -0082 if ~model.ec.geckoLight
    -0083     rxnNames = model.ec.rxns;
    -0084 else
    -0085     rxnNames = extractAfter(model.ec.rxns, 4);
    -0086 end
    -0087 [~,originalRxns] = ismember(rxnNames(ecRxns),model.rxns);
    -0088 for i = 1:length(ecRxns)
    -0089     sel = find(model.S(:,originalRxns(i)) < 0);
    -0090     substrates{i}  = model.metNames(sel); 
    -0091     substrCoeffs{i} = -model.S(sel,originalRxns(i));
    -0092 end
    -0093 
    -0094 %Load BRENDA data:
    -0095 [KCATcell, SAcell] = loadBRENDAdata(modelAdapter);
    -0096 
    -0097 %Creates a Structure with KEGG codes for organisms, names and taxonomical
    -0098 %distance matrix and extract the organism index in the KEGG struct
    -0099 phylDistStruct =  KEGG_struct(modelAdapter.getPhylDistStructPath());
    -0100 %Get the KEGG code for the model's organism
    -0101 org_name       = params.org_name;
    -0102 org_index      = find_inKEGG(org_name,phylDistStruct.names);
    -0103 %build an index for genus in the phyl dist struct
    -0104 %first just extract the genus (i.e. the first part of the name)
    -0105 phylDistStruct.genus = lower(regexprep(phylDistStruct.names,'\s.*',''));
    -0106 %create a map for the genuses
    -0107 phylDistStruct.uniqueGenusList = unique(phylDistStruct.genus);
    -0108 phylDistStruct.genusHashMap = containers.Map(phylDistStruct.uniqueGenusList,1:length(phylDistStruct.uniqueGenusList));
    -0109 phylDistStruct.uniqueGenusIndices = cell(length(phylDistStruct.uniqueGenusList),1);
    -0110 
    -0111 %Then for each genus create a list with indices to the names
    -0112 for i = 1:length(phylDistStruct.genus)
    -0113     matchInd = cell2mat(values(phylDistStruct.genusHashMap,phylDistStruct.genus(i)));
    -0114     phylDistStruct.uniqueGenusIndices{matchInd} = [phylDistStruct.uniqueGenusIndices{matchInd};i];
    -0115 end
    -0116 
    -0117 %Allocate output
    -0118 kcats = zeros(length(eccodes),1);
    -0119 mM = length(eccodes);
    -0120 
    -0121 %Create empty kcatInfo
    -0122 %Legacy, no longer given as output, rather used to construct
    -0123 %kcatList.wildcardLvl and kcatList.origin.
    -0124 kcatInfo.info.org_s   = zeros(mM,1);
    -0125 kcatInfo.info.rest_s  = zeros(mM,1);
    -0126 kcatInfo.info.org_ns  = zeros(mM,1);
    -0127 kcatInfo.info.rest_ns = zeros(mM,1);
    -0128 kcatInfo.info.org_sa  = zeros(mM,1);
    -0129 kcatInfo.info.rest_sa = zeros(mM,1);
    -0130 kcatInfo.info.wcLevel = NaN(mM,1);
    -0131 kcatInfo.stats.queries  = 0;
    -0132 kcatInfo.stats.org_s    = 0;
    -0133 kcatInfo.stats.rest_s   = 0;
    -0134 kcatInfo.stats.org_ns   = 0;
    -0135 kcatInfo.stats.rest_ns  = 0;
    -0136 kcatInfo.stats.org_sa   = 0;
    -0137 kcatInfo.stats.rest_sa  = 0;
    -0138 kcatInfo.stats.wc0      = 0;
    -0139 kcatInfo.stats.wc1      = 0;
    -0140 kcatInfo.stats.wc2      = 0;
    -0141 kcatInfo.stats.wc3      = 0;
    -0142 kcatInfo.stats.wc4      = 0;
    -0143 kcatInfo.stats.matrix   = zeros(6,5);
    -0144 
    -0145 %build an EC index to speed things up a bit - many of the ECs appear
    -0146 %many times - unnecessary to compare them all
    -0147 %so, here, each EC string appears only once, and you get a vector with
    -0148 %indices to the rows in KCATcell
    -0149 [ECIndexIds,~,ic] = unique(KCATcell{1});
    -0150 EcIndexIndices = cell(length(ECIndexIds),1);
    -0151 for i = 1:length(EcIndexIndices)
    -0152     EcIndexIndices{i} = find(ic == i).';
    -0153 end
    -0154 
    -0155 %Apply force wildcard level
    -0156 while forceWClvl > 0
    -0157     eccodes=regexprep(eccodes,'(.)*(\.\d+)(\.-)*$','$1\.-$3');
    -0158     forceWClvl = forceWClvl - 1;
    -0159 end
    -0160 if forceWClvl == 1
    -0161     eccodes = regexprep(eccodes,'.*','-\.-\.-\.-');
    -0162 end
    -0163 
    -0164 progressbar('Gathering kcat values by fuzzy matching to BRENDA database')
    -0165 %Main loop:
    -0166 for i = 1:mM
    -0167     %Match:
    -0168     EC = eccodes{i};
    -0169     if ~isempty(EC)
    -0170         EC = strsplit(EC,';');
    -0171         %Try to match direct reaction:
    -0172         if ~isempty(substrates{i})
    -0173             [kcats(i), kcatInfo.info,kcatInfo.stats] = iterativeMatch(EC,substrates{i},substrCoeffs{i},i,KCATcell,...
    -0174                 kcatInfo.info,kcatInfo.stats,org_name,...
    -0175                 phylDistStruct,org_index,SAcell,ECIndexIds,EcIndexIndices);
    -0176         end
    -0177     end
    -0178     progressbar(i/mM)
    -0179 end
    -0180 
    -0181 kcatList.source      = 'brenda';
    -0182 kcatList.rxns        = model.ec.rxns(ecRxns);
    -0183 kcatList.substrates  = substrates;
    -0184 kcatList.kcats       = kcats;
    -0185 kcatList.eccodes     = eccodes;
    -0186 kcatList.wildcardLvl = kcatInfo.info.wcLevel;
    -0187 kcatList.origin      = NaN(numel(model.ec.rxns(ecRxns)),1);
    -0188 % This can be refactored, iterativeMatch and their nested functions can
    -0189 % just directly report the origin number.
    -0190 origin = [kcatInfo.info.org_s kcatInfo.info.rest_s kcatInfo.info.org_ns kcatInfo.info.rest_ns kcatInfo.info.org_sa kcatInfo.info.rest_sa];
    -0191 for i=1:6
    -0192     kcatList.origin(find(origin(:,i))) = i;
    -0193 end
    -0194 end
    -0195 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0196 function [kcat,dir,tot] =iterativeMatch(EC,subs,substrCoeff,i,KCATcell,dir,tot,...
    -0197     name,phylDist,org_index,SAcell,ECIndexIds,EcIndexIndices)
    -0198 %Will iteratively try to match the EC number to some registry in BRENDA,
    -0199 %using each time one additional wildcard.
    -0200 
    -0201 kcat    = zeros(size(EC));
    -0202 origin  = zeros(size(EC));
    -0203 matches = zeros(size(EC));
    -0204 wc_num  = ones(size(EC)).*1000;
    -0205 for k = 1:length(EC)
    -0206     success  = false;
    -0207     while ~success
    -0208         %Atempt match:
    -0209         [kcat(k),origin(k),matches(k)] = mainMatch(EC{k},subs,substrCoeff,KCATcell,...
    -0210             name,phylDist,...
    -0211             org_index,SAcell,ECIndexIds,EcIndexIndices);
    -0212         %If any match found, ends. If not, introduces one extra wild card and
    -0213         %tries again:
    -0214         if origin(k) > 0
    -0215             success   = true;
    -0216             wc_num(k) = sum(EC{k}=='-');
    -0217         else
    -0218             dot_pos  = [2 strfind(EC{k},'.')];
    -0219             wild_num = sum(EC{k}=='-');
    -0220             wc_text  = '-.-.-.-';
    -0221             EC{k}    = [EC{k}(1:dot_pos(4-wild_num)) wc_text(1:2*wild_num+1)];
    -0222         end
    -0223     end
    -0224 end
    -0225 
    -0226 if sum(origin) > 0
    -0227     %For more than one EC: Choose the maximum value among the ones with the
    -0228     %less amount of wildcards and the better origin:
    -0229     best_pos   = (wc_num == min(wc_num));
    -0230     new_origin = origin(best_pos);
    -0231     best_pos   = (origin == min(new_origin(new_origin~=0)));
    -0232     max_pos    = find(kcat == max(kcat(best_pos)));
    -0233     wc_num     = wc_num(max_pos(1));
    -0234     origin     = origin(max_pos(1));
    -0235     matches    = matches(max_pos(1));
    -0236     kcat       = kcat(max_pos(1));
    -0237 
    -0238     %Update dir and tot:
    -0239     dir.org_s(i)   = matches*(origin == 1);
    -0240     dir.rest_s(i)  = matches*(origin == 2);
    -0241     dir.org_ns(i)  = matches*(origin == 3);
    -0242     dir.org_sa(i)  = matches*(origin == 4);
    -0243     dir.rest_ns(i) = matches*(origin == 5);
    -0244     dir.rest_sa(i) = matches*(origin == 6);
    -0245     dir.wcLevel(i) = wc_num;
    -0246     tot.org_s        = tot.org_s   + (origin == 1);
    -0247     tot.rest_s       = tot.rest_s  + (origin == 2);
    -0248     tot.org_ns       = tot.org_ns  + (origin == 3);
    -0249     tot.org_sa       = tot.org_sa  + (origin == 4);
    -0250     tot.rest_ns      = tot.rest_ns + (origin == 5);
    -0251     tot.rest_sa      = tot.rest_sa + (origin == 6);
    -0252     tot.wc0          = tot.wc0     + (wc_num == 0);
    -0253     tot.wc1          = tot.wc1     + (wc_num == 1);
    -0254     tot.wc2          = tot.wc2     + (wc_num == 2);
    -0255     tot.wc3          = tot.wc3     + (wc_num == 3);
    -0256     tot.wc4          = tot.wc4     + (wc_num == 4);
    -0257     tot.queries      = tot.queries + 1;
    -0258     tot.matrix(origin,wc_num+1) = tot.matrix(origin,wc_num+1) + 1;
    -0259 end
    -0260 
    -0261 end
    -0262 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0263 
    -0264 function [kcat,origin,matches] = mainMatch(EC,subs,substrCoeff,KCATcell,...
    -0265     name,phylDist,org_index,SAcell,ECIndexIds,EcIndexIndices)
    -0266 
    -0267 %First make the string matching. This takes time, so we only want to do
    -0268 %this once:
    -0269 %Relaxes matching if wild cards are present:
    -0270 wild     = false;
    -0271 wild_pos = strfind(EC,'-');
    -0272 if ~isempty(wild_pos)
    -0273     EC   = EC(1:wild_pos(1)-1);
    -0274     wild = true;
    -0275 end
    -0276 stringMatchesEC_cell = extract_string_matches(EC,KCATcell{1},wild,ECIndexIds,EcIndexIndices);
    -0277 
    -0278 % Matching function prioritizing organism and substrate specificity when
    -0279 % available.
    -0280 
    -0281 origin = 0;
    -0282 %First try to match organism and substrate:
    -0283 [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,name,true,false,...
    -0284     phylDist,org_index,SAcell,stringMatchesEC_cell,[]);
    -0285 if matches > 0 && ~wild % If wildcard, ignore substrate match
    -0286     origin = 1;
    -0287     %If no match, try the closest organism but match the substrate:
    -0288 else
    -0289     [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,'',true,false,...
    -0290         phylDist,org_index,SAcell,stringMatchesEC_cell,[]);
    -0291     if matches > 0 && ~wild % If wildcard, ignore substrate match
    -0292         origin = 2;
    -0293         %If no match, try to match organism but with any substrate:
    -0294     else
    -0295         [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,name,false,false,...
    -0296             phylDist,org_index,SAcell,stringMatchesEC_cell,[]);
    -0297         if matches > 0
    -0298             origin = 3;
    -0299             %If no match, try to match organism but for any substrate (SA*MW):
    -0300         else
    -0301             %create matching index for SA, has not been needed until now
    -0302             stringMatchesSA = extract_string_matches(EC,SAcell{1},wild,[],[]);
    -0303 
    -0304             [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,name,false,...
    -0305                 true,phylDist,org_index,...
    -0306                 SAcell,stringMatchesEC_cell,stringMatchesSA);
    -0307             if matches > 0
    -0308                 origin = 4;
    -0309                 %If no match, try any organism and any substrate:
    -0310             else
    -0311                 [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,'',false,...
    -0312                     false,phylDist,...
    -0313                     org_index,SAcell,stringMatchesEC_cell,stringMatchesSA);
    -0314                 if matches > 0
    -0315                     origin = 5;
    -0316                     %Again if no match, look for any org and SA*MW
    -0317                 else
    -0318                     [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,'',...
    -0319                         false,true,phylDist,...
    -0320                         org_index,SAcell,stringMatchesEC_cell,stringMatchesSA);
    -0321                     if matches > 0
    -0322                         origin = 6;
    -0323                     end
    -0324                 end
    -0325 
    -0326             end
    -0327         end
    -0328     end
    -0329 end
    -0330 end
    -0331 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0332 function [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,organism,...
    -0333     substrate,SA,phylDist,...
    -0334     org_index,SAcell,KCATcellMatches,SAcellMatches)
    -0335 
    -0336 %Will go through BRENDA and will record any match. Afterwards, it will
    -0337 %return the average value and the number of matches attained.
    -0338 kcat    = [];
    -0339 matches = 0;
    -0340 
    -0341 if SA
    -0342     %SAcell{1},wild,[],[]
    -0343     EC_indexes = extract_indexes(SAcellMatches,[],SAcell{2},subs,substrate,...
    -0344         organism,org_index,phylDist);
    -0345 
    -0346     kcat       = SAcell{3}(EC_indexes);
    -0347     org_cell   = SAcell{2}(EC_indexes);
    -0348     MW_BRENDA  = SAcell{4}(EC_indexes);
    -0349 
    -0350 else
    -0351     %KCATcell{1},wild,ECIndexIds,EcIndexIndices
    -0352     EC_indexes = extract_indexes(KCATcellMatches,KCATcell{2},KCATcell{3},...
    -0353         subs,substrate,organism,org_index,...
    -0354         phylDist);
    -0355     if substrate
    -0356         for j = 1:length(EC_indexes)
    -0357             indx = EC_indexes(j);
    -0358             for k = 1:length(subs)
    -0359                 if (isempty(subs{k}))
    -0360                     break;
    -0361                 end
    -0362                 %l = logical(strcmpi(model.metNames,subs{k}).*(model.S(:,i)~=0)); %I don't understand the .* (model.S(:,i)~=0) part, it shouldn't be needed?/JG;
    -0363                 if ~isempty(subs{k}) && strcmpi(subs{k},KCATcell{2}(indx))
    -0364                     if KCATcell{4}(indx) > 0
    -0365                         coeff = min(substrCoeff);
    -0366                         kCatTmp = KCATcell{4}(indx);
    -0367                         kcat  = [kcat;kCatTmp/coeff];
    -0368                     end
    -0369                 end
    -0370             end
    -0371         end
    -0372     else
    -0373         kcat = KCATcell{4}(EC_indexes);
    -0374     end
    -0375 end
    -0376 %Return maximum value:
    -0377 if isempty(kcat)
    -0378     kcat = 0;
    -0379 else
    -0380     matches        = length(kcat);
    -0381     [kcat,MaxIndx] = max(kcat);
    -0382 end
    -0383 %Avoid SA*Mw values over the diffusion limit rate  [Bar-Even et al. 2011]
    -0384 if kcat>(1E7)
    -0385     kcat = 1E7;
    -0386 end
    -0387 end
    -0388 
    -0389 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0390 %Make the string matches of the ECs. This is heavy, so only do it once!
    -0391 %
    -0392 function EC_indexes = extract_string_matches(EC,EC_cell,wild,ECIndexIds,EcIndexIndices)
    -0393 EC_indexes = [];
    -0394 EC_indexesOld = [];
    -0395 if wild
    -0396     if (~isempty(ECIndexIds)) %In some cases the EC_cell is not from KCatCell
    -0397         X = find(contains(ECIndexIds, EC));
    -0398         for j = 1:length(X)
    -0399             EC_indexes = [EC_indexes,EcIndexIndices{X(j)}];
    -0400         end
    -0401     else %Not optimized
    -0402         for j=1:length(EC_cell)
    -0403             if strfind(EC_cell{j},EC)==1
    -0404                 EC_indexes = [EC_indexes,j];
    -0405             end
    -0406         end
    -0407     end
    -0408 else
    -0409     if (~isempty(ECIndexIds)) %In some cases the EC_cell is not from KCatCell
    -0410         mtch = find(strcmpi(EC,ECIndexIds));
    -0411         if (~isempty(mtch))
    -0412             EC_indexes = EcIndexIndices{mtch};
    -0413         end
    -0414     else %%Not optimized
    -0415         if ~isempty(EC_cell)
    -0416             EC_indexes = transpose(find(strcmpi(EC,EC_cell)));
    -0417         end
    -0418     end
    -0419 end
    -0420 
    -0421 end
    -0422 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0423 %Extract the indexes of the entries in the BRENDA data that meet the
    -0424 %conditions specified by the search criteria
    -0425 function EC_indexes = extract_indexes(EC_indCellStringMatches,subs_cell,orgs_cell,subs,...
    -0426     substrate,organism, org_index,...
    -0427     phylDist)
    -0428 
    -0429 EC_indexes = EC_indCellStringMatches;%reuse so the string comparisons are not run many times
    -0430 
    -0431 %If substrate=true then it will extract only the substrates appereances
    -0432 %indexes in the EC subset from the BRENDA cell array
    -0433 
    -0434 if substrate
    -0435     if (~isempty(EC_indexes)) %optimization
    -0436         Subs_indexes = [];
    -0437         for l = 1:length(subs)
    -0438             if (isempty(subs{l}))
    -0439                 break;
    -0440             end
    -0441             Subs_indexes = horzcat(Subs_indexes,EC_indexes(strcmpi(subs(l),...
    -0442                 subs_cell(EC_indexes))));
    -0443         end
    -0444         EC_indexes = Subs_indexes;
    -0445     end
    -0446 end
    -0447 
    -0448 EC_orgs = orgs_cell(EC_indexes);
    -0449 %If specific organism values are requested looks for all the organism
    -0450 %repetitions on the subset BRENDA cell array(EC_indexes)
    -0451 if string(organism) ~= ''
    -0452     EC_indexes = EC_indexes(strcmpi(string(organism),EC_orgs));
    -0453 
    -0454     %If KEGG code was assigned to the organism (model) then it will look for
    -0455     %the Kcat value for the closest organism
    -0456 elseif org_index~='*' %&& org_index~=''
    -0457     KEGG_indexes = [];temp = [];
    -0458 
    -0459     %For relating a phyl dist between the modelled organism and the organisms
    -0460     %on the BRENDA cell array it should search for a KEGG code for each of
    -0461     %these
    -0462     for j=1:length(EC_indexes)
    -0463         %Assigns a KEGG index for those found on the KEGG struct
    -0464         orgs_index = find(strcmpi(orgs_cell(EC_indexes(j)),phylDist.names),1);
    -0465         if ~isempty(orgs_index)
    -0466             KEGG_indexes = [KEGG_indexes; orgs_index];
    -0467             temp         = [temp;EC_indexes(j)];
    -0468             %For values related to organisms without KEGG code, then it will
    -0469             %look for KEGG code for the first organism with the same genus
    -0470         else
    -0471             org = orgs_cell{EC_indexes(j)};
    -0472             orgGenus = lower(regexprep(org,'\s.*',''));
    -0473             if isKey(phylDist.genusHashMap,orgGenus) %annoyingly, this seems to be needed
    -0474                 matchInd = cell2mat(values(phylDist.genusHashMap,{orgGenus}));
    -0475                 matches = phylDist.uniqueGenusIndices{matchInd};
    -0476                 k = matches(1);
    -0477                 KEGG_indexes = [KEGG_indexes;k];
    -0478                 temp         = [temp;EC_indexes(j)];
    -0479             end
    -0480         end
    -0481     end
    -0482     %Update the EC_indexes cell array
    -0483     EC_indexes = temp;
    -0484     %Looks for the taxonomically closest organism and saves the index of
    -0485     %its appearences in the BRENDA cell
    -0486     if ~isempty(EC_indexes)
    -0487         distances = phylDist.distMat(org_index,KEGG_indexes);
    -0488         EC_indexes = EC_indexes(distances == min(distances));
    -0489     end
    -0490 end
    -0491 end
    -0492 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0493 function org_index = find_inKEGG(org_name,names)
    -0494 org_index      = find(strcmpi(org_name,names));
    -0495 if numel(org_index)>1
    -0496     org_index = org_index(1);
    -0497 elseif isempty(org_index)
    -0498     org_name    = regexprep(org_name,'\s.*','');
    -0499     org_index   = find(strcmpi(org_name,names));
    -0500     if numel(org_index)>1
    -0501         org_index = org_index(1);
    -0502     elseif isempty(org_index)
    -0503         org_index = '*';
    -0504     end
    -0505 end
    -0506 end
    -0507 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0508 function phylDistStruct =  KEGG_struct(phylpath)
    -0509 load(phylpath)
    -0510 phylDistStruct.ids   = transpose(phylDistStruct.ids);
    -0511 phylDistStruct.names = transpose(phylDistStruct.names);
    -0512 phylDistStruct.names = regexprep(phylDistStruct.names,'\s*\(.*','');
    -0513 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/gather_kcats/getStandardKcat.html b/doc/src/geckomat/gather_kcats/getStandardKcat.html deleted file mode 100644 index f412d53f..00000000 --- a/doc/src/geckomat/gather_kcats/getStandardKcat.html +++ /dev/null @@ -1,419 +0,0 @@ - - - - Description of getStandardKcat - - - - - - - - - -
    Home > src > geckomat > gather_kcats > getStandardKcat.m
    - - - -

    getStandardKcat -

    - -

    PURPOSE ^

    -
    getStandardKcat
    - -

    SYNOPSIS ^

    -
    function [model, rxnsMissingGPR, standardMW, standardKcat, rxnsNoKcat] = getStandardKcat(model, modelAdapter, threshold, fillZeroKcat)
    - -

    DESCRIPTION ^

    -
     getStandardKcat
    -   Calculate an standard kcat and standard molecular weight (MW) that can
    -   be used to apply enzyme constraints to reactions without any associated
    -   enzymes. Such reactions have either an empty model.grRules field, or
    -   they have no match in model.ec.rxns (which can be the case if the genes
    -   in the model.grRules field could not be mapped to enzymes). This is
    -   done by adding those reactions to model.ec, assign a "standard"
    -   pseudoenzyme with the standard MW (median of all proteins in the
    -   organism) and standard kcat (median from all kcat, or subsystem
    -   specific kcat).
    -
    -   A reaction is assigned a subSystem specific kcat values if the model
    -   has a subSystems field and the reaction is annotated with a subSystem.
    -   Only the first subSystem will be considered if multiple are annotated
    -   to the same reaction.
    -
    -   Exchange, transport and pseudoreactions are filtered out, plus any
    -   reaction identifiers specified in /data/pseudoRxns.tsv in the model
    -   adapter folder.
    -
    -   In addition, reactions that are annotated with an enzyme (and therefore
    -   already in model.ec), but not assigned any reaction-specific kcat value
    -   (their model.ec.kcat entry is either 0 or NaN), can be assigned
    -   standard kcat values by a similar approach. However, those reactions
    -   will not be linked to the "standard" pseudoenzyme, but will use the
    -   enzyme that they had already been associated with.
    -
    -   Any pre-existing standard kcat assignments (identified by 'standard'
    -   entires in model.ec.source) are removed when applying this function.
    -
    - Input:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use
    -                   the default model adapter).
    -   threshold       a threshold to determine when use a kcat value based on
    -                   the mean kcat of the reactions in the same subSystem or
    -                   based on the median value of all the kcat in the model.
    -                   Second option is used when the number of reactions in a
    -                   determined subSystem is < threshold. (Optional, default
    -                   = 10)
    -   fillZeroKcat    logical whether zero kcat values should be replaced
    -                   with standard kcat values. (Optional, default = true).
    -
    - Output:
    -   model           ecModel where model.ec is expanded with a standard
    -                   protein with standard kcat and standard MW, assigned to
    -                   reactions without gene associations.
    -   rxnsMissingGPR  a list of updated rxns identifiers with a standard value
    -   standardMW      the standard MW value calculated
    -   standardKcat    the standard Kcat value calculated 
    -   rxnsNoKcat      a list of rxns identifiers whose zero kcat has been replaced
    -
    -   While model.ec.kcat is populated, applyKcatConstraints would still need
    -   to be run to apply the new constraints to the S-matrix.
    -
    - Usage:
    -    [model, rxnsMissingGPR, standardMW, standardKcat, rxnsNoKcat] = getStandardKcat(model, modelAdapter, threshold, fillZeroKcat);
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 function [model, rxnsMissingGPR, standardMW, standardKcat, rxnsNoKcat] = getStandardKcat(model, modelAdapter, threshold, fillZeroKcat)
    -0002 % getStandardKcat
    -0003 %   Calculate an standard kcat and standard molecular weight (MW) that can
    -0004 %   be used to apply enzyme constraints to reactions without any associated
    -0005 %   enzymes. Such reactions have either an empty model.grRules field, or
    -0006 %   they have no match in model.ec.rxns (which can be the case if the genes
    -0007 %   in the model.grRules field could not be mapped to enzymes). This is
    -0008 %   done by adding those reactions to model.ec, assign a "standard"
    -0009 %   pseudoenzyme with the standard MW (median of all proteins in the
    -0010 %   organism) and standard kcat (median from all kcat, or subsystem
    -0011 %   specific kcat).
    -0012 %
    -0013 %   A reaction is assigned a subSystem specific kcat values if the model
    -0014 %   has a subSystems field and the reaction is annotated with a subSystem.
    -0015 %   Only the first subSystem will be considered if multiple are annotated
    -0016 %   to the same reaction.
    -0017 %
    -0018 %   Exchange, transport and pseudoreactions are filtered out, plus any
    -0019 %   reaction identifiers specified in /data/pseudoRxns.tsv in the model
    -0020 %   adapter folder.
    -0021 %
    -0022 %   In addition, reactions that are annotated with an enzyme (and therefore
    -0023 %   already in model.ec), but not assigned any reaction-specific kcat value
    -0024 %   (their model.ec.kcat entry is either 0 or NaN), can be assigned
    -0025 %   standard kcat values by a similar approach. However, those reactions
    -0026 %   will not be linked to the "standard" pseudoenzyme, but will use the
    -0027 %   enzyme that they had already been associated with.
    -0028 %
    -0029 %   Any pre-existing standard kcat assignments (identified by 'standard'
    -0030 %   entires in model.ec.source) are removed when applying this function.
    -0031 %
    -0032 % Input:
    -0033 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0034 %   modelAdapter    a loaded model adapter (Optional, will otherwise use
    -0035 %                   the default model adapter).
    -0036 %   threshold       a threshold to determine when use a kcat value based on
    -0037 %                   the mean kcat of the reactions in the same subSystem or
    -0038 %                   based on the median value of all the kcat in the model.
    -0039 %                   Second option is used when the number of reactions in a
    -0040 %                   determined subSystem is < threshold. (Optional, default
    -0041 %                   = 10)
    -0042 %   fillZeroKcat    logical whether zero kcat values should be replaced
    -0043 %                   with standard kcat values. (Optional, default = true).
    -0044 %
    -0045 % Output:
    -0046 %   model           ecModel where model.ec is expanded with a standard
    -0047 %                   protein with standard kcat and standard MW, assigned to
    -0048 %                   reactions without gene associations.
    -0049 %   rxnsMissingGPR  a list of updated rxns identifiers with a standard value
    -0050 %   standardMW      the standard MW value calculated
    -0051 %   standardKcat    the standard Kcat value calculated
    -0052 %   rxnsNoKcat      a list of rxns identifiers whose zero kcat has been replaced
    -0053 %
    -0054 %   While model.ec.kcat is populated, applyKcatConstraints would still need
    -0055 %   to be run to apply the new constraints to the S-matrix.
    -0056 %
    -0057 % Usage:
    -0058 %    [model, rxnsMissingGPR, standardMW, standardKcat, rxnsNoKcat] = getStandardKcat(model, modelAdapter, threshold, fillZeroKcat);
    -0059 
    -0060 if nargin < 2 || isempty(modelAdapter)
    -0061     modelAdapter = ModelAdapterManager.getDefault();
    -0062     if isempty(modelAdapter)
    -0063         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0064     end
    -0065 end
    -0066 params = modelAdapter.getParameters();
    -0067 
    -0068 if nargin < 3 || isempty(threshold)
    -0069     threshold = 10;
    -0070 end
    -0071 
    -0072 if nargin < 4 || isempty(fillZeroKcat)
    -0073     fillZeroKcat = true;
    -0074 end
    -0075 
    -0076 databases = loadDatabases('uniprot', modelAdapter);
    -0077 
    -0078 % An standard MW is defined for all the rxns which does not have a GPR
    -0079 % rule defined. This is based in all the proteins reported for the specific
    -0080 % organism in uniprot
    -0081 standardMW = median(databases.uniprot.MW, 'omitnan');
    -0082 
    -0083 % An standard Kcat is defined for all the rxns which does not have a GPR
    -0084 % rule defined. In this case, the kcat value for a particular reaction is
    -0085 % defined as the mean of the kcat values of the reactions involved in the
    -0086 % same subsystem in which the given reaction is involved. Nevertheless, if
    -0087 % a subSystem have a number of reactions lower than a treshold, the kcat
    -0088 % value will be the median of the kcat in all the reactions of the model.
    -0089 
    -0090 % Remove from the list those with kcat zero
    -0091 rxnsKcatZero = model.ec.kcat > 0;
    -0092 
    -0093 % Get the kcat value based on all the kcats in the model
    -0094 standardKcat = median(model.ec.kcat(rxnsKcatZero), 'omitnan');
    -0095 
    -0096 % If the model have subSystems assigned calculate kcat based on subSystem
    -0097 if isfield(model,'subSystems') && ~all(cellfun(@isempty, model.subSystems))
    -0098     standard = false;
    -0099     if model.ec.geckoLight
    -0100         modRxns = extractAfter(model.ec.rxns,4);
    -0101     else
    -0102         modRxns = model.ec.rxns;
    -0103     end
    -0104     % Map ec-rxns to model.rxns
    -0105     [~,rxnIdx]  = ismember(modRxns,model.rxns);
    -0106     % Choose first subSystem
    -0107     enzSubSystems = flattenCell(model.subSystems(rxnIdx));
    -0108     enzSubSystems = enzSubSystems(:,1);
    -0109     if ~all(cellfun(@isempty, enzSubSystems))
    -0110 
    -0111     % Make list of unique subsystems, and which rxns are linked to them
    -0112     [enzSubSystem_names, ~, rxnToSub] = unique(enzSubSystems);
    -0113     % Make matrix of ec-rxns vs. unique subsystem index
    -0114     ind = sub2ind([numel(enzSubSystem_names) numel(enzSubSystems)],rxnToSub',1:numel(rxnToSub));
    -0115     kcatSubSystem = false([numel(enzSubSystem_names) numel(enzSubSystems)]);
    -0116     kcatSubSystem(ind) = true;
    -0117     % Number of kcats per subSystem
    -0118     kcatsPerSubSystem = sum(kcatSubSystem,2);
    -0119     % Calculate average kcat values per subSystem
    -0120     kcatSubSystem = (kcatSubSystem*model.ec.kcat)./kcatsPerSubSystem;
    -0121     kcatSubSystem(kcatsPerSubSystem < threshold) = standardKcat;
    -0122     else
    -0123         standard = true;
    -0124         printOrange('WARNING: No subSystem-specific kcat values can be calculated');
    -0125     end
    -0126 else
    -0127     standard = true;
    -0128     printOrange('WARNING: No subSystem-specific kcat values can be calculated');
    -0129 end
    -0130 
    -0131 % Find reactions without GPR
    -0132 rxnsMissingGPR = find(cellfun(@isempty, model.grRules));
    -0133 
    -0134 % Find reactions with GPR but without model.ec entry (for instance due to
    -0135 % no protein matching)
    -0136 rxnsMissingEnzyme = find(~cellfun(@isempty, model.grRules));
    -0137 if model.ec.geckoLight
    -0138     ecRxnsList = unique(extractAfter(model.ec.rxns,4));
    -0139 else
    -0140     ecRxnsList = model.ec.rxns;
    -0141 end
    -0142 rxnsMissingEnzyme = find(and(~ismember(model.rxns(rxnsMissingEnzyme),ecRxnsList), ~contains(model.rxns(rxnsMissingEnzyme),'usage_prot_')));
    -0143 rxnsMissingGPR = [rxnsMissingGPR;rxnsMissingEnzyme];
    -0144 
    -0145 % Get custom list of reaction IDs to ignore, if existing. First column
    -0146 % contains reaction IDs, second column contains reaction names for
    -0147 % reference only.
    -0148 if exist(fullfile(params.path,'data','pseudoRxns.tsv'),'file')
    -0149     fID        = fopen(fullfile(params.path,'data','pseudoRxns.tsv'));
    -0150     fileData   = textscan(fID,'%s %s','delimiter','\t');
    -0151     fclose(fID);
    -0152     customRxns = fileData{1};
    -0153     customRxns = find(ismember(model.rxns,customRxns));
    -0154 else
    -0155     customRxns = [];
    -0156 end
    -0157 % Get and remove exchange, transport, spontaneous and pseudo reactions
    -0158 [~, exchangeRxns]  = getExchangeRxns(model);
    -0159 transportRxns = getTransportRxns(model);
    -0160 [spontaneousRxns, ~] = modelAdapter.getSpontaneousReactions(model);
    -0161 pseudoRxns = contains(model.rxnNames,'pseudoreaction');
    -0162 slimeRxns = contains(model.rxnNames,'SLIME rxn');
    -0163 rxnsToIgnore = [customRxns; exchangeRxns; find(transportRxns); ...
    -0164                 find(spontaneousRxns); find(pseudoRxns); find(slimeRxns)];
    -0165 rxnsMissingGPR(ismember(rxnsMissingGPR, rxnsToIgnore)) = [];
    -0166 
    -0167 % Only add if not geckoLight & getStandardKcat was not run earlier
    -0168 if ~any(strcmp(model.mets,'prot_standard'))
    -0169     % Add a new gene to be consistent with ec field named standard
    -0170     proteinStdGenes.genes = 'standard';
    -0171     if isfield(model,'geneShortNames')
    -0172         proteinStdGenes.geneShortNames = 'std';
    -0173     end
    -0174     model = addGenesRaven(model, proteinStdGenes);
    -0175 
    -0176     if ~model.ec.geckoLight
    -0177         % Add a new metabolite named prot_standard
    -0178         proteinStdMets.mets         = 'prot_standard';
    -0179         proteinStdMets.metNames     = proteinStdMets.mets;
    -0180         % Validate compartment
    -0181         compartmentID = strcmp(model.compNames,params.enzyme_comp);
    -0182         if ~any(compartmentID)
    -0183             error(['Compartment ' params.enzyme_comp ' (specified in params.enzyme_comp) '...
    -0184                 'cannot be found in model.compNames'])
    -0185         end
    -0186         proteinStdMets.compartments = model.comps(compartmentID);
    -0187 
    -0188         if isfield(model,'metNotes')
    -0189             proteinStdMets.metNotes = 'Standard enzyme-usage pseudometabolite';
    -0190         end
    -0191         model = addMets(model, proteinStdMets);
    -0192 
    -0193         % Add a protein usage reaction if not a light version
    -0194         proteinStdUsageRxn.rxns         = {'usage_prot_standard'};
    -0195         proteinStdUsageRxn.rxnNames     = proteinStdUsageRxn.rxns;
    -0196         proteinStdUsageRxn.mets         = {proteinStdMets.mets, 'prot_pool'};
    -0197         proteinStdUsageRxn.stoichCoeffs = [-1, 1];
    -0198         proteinStdUsageRxn.lb           = -1000;
    -0199         proteinStdUsageRxn.ub           = 0;
    -0200         proteinStdUsageRxn.grRules      = proteinStdGenes.genes;
    -0201 
    -0202         model = addRxns(model, proteinStdUsageRxn);
    -0203     end
    -0204     % Update .ec structure in model
    -0205     model.ec.genes(end+1)      = {'standard'};
    -0206     model.ec.enzymes(end+1)    = {'standard'};
    -0207     model.ec.mw(end+1)         = standardMW;
    -0208     model.ec.sequence(end+1)   = {''};
    -0209     % Additional info
    -0210     if isfield(model.ec,'concs')
    -0211         model.ec.concs(end+1)  = nan();
    -0212     end
    -0213 
    -0214     % Expand the enzyme rxns matrix
    -0215     model.ec.rxnEnzMat =  [model.ec.rxnEnzMat, zeros(length(model.ec.rxns), 1)]; % 1 new enzyme
    -0216     model.ec.rxnEnzMat =  [model.ec.rxnEnzMat; zeros(length(rxnsMissingGPR), length(model.ec.enzymes))]; % new rxns
    -0217 end
    -0218 stdMetIdx = find(strcmpi(model.ec.enzymes, 'standard'));
    -0219 
    -0220 % Remove previous standard kcat assignment
    -0221 oldStandardEnz = find(strcmp(model.ec.source,'standard'));
    -0222 if ~isempty(oldStandardEnz)
    -0223     oldStandardProt = logical(model.ec.rxnEnzMat(oldStandardEnz,stdMetIdx));
    -0224     % If annotated with real enzyme => set kcat to zero
    -0225     model.ec.kcat(oldStandardEnz(~oldStandardProt))        = 0;
    -0226     model.ec.source(oldStandardEnz(~oldStandardProt))      = {''};
    -0227     % If annotated with standard protein => remove entry
    -0228     model.ec.rxns(oldStandardEnz(oldStandardProt))        = [];
    -0229     model.ec.kcat(oldStandardEnz(oldStandardProt))        = [];
    -0230     model.ec.source(oldStandardEnz(oldStandardProt))      = [];
    -0231     model.ec.notes(oldStandardEnz(oldStandardProt))       = [];
    -0232     model.ec.eccodes(oldStandardEnz(oldStandardProt))     = [];
    -0233     model.ec.rxnEnzMat(oldStandardEnz(oldStandardProt),:) = [];
    -0234 end
    -0235 
    -0236 numRxns = length(model.ec.rxns);
    -0237 for i = 1:numel(rxnsMissingGPR)
    -0238     rxnIdx = rxnsMissingGPR(i);
    -0239 
    -0240     % Update .ec structure in model
    -0241     if ~model.ec.geckoLight
    -0242         model.ec.rxns(end+1)     = model.rxns(rxnIdx);
    -0243         % Add prefix in case is light version
    -0244     else
    -0245         model.ec.rxns{end+1}     = ['001_' model.rxns{rxnIdx}];
    -0246     end
    -0247 
    -0248     if ~standard
    -0249         kcatSubSystemIdx = strcmpi(enzSubSystem_names, model.subSystems{rxnIdx}(1));
    -0250         if all(kcatSubSystemIdx)
    -0251             model.ec.kcat(end+1) = kcatSubSystem(kcatSubSystemIdx);
    -0252         else
    -0253             model.ec.kcat(end+1) = standardKcat;
    -0254         end
    -0255     else
    -0256         model.ec.kcat(end+1) = standardKcat;
    -0257     end
    -0258 
    -0259     model.ec.source(end+1)   = {'standard'};
    -0260     model.ec.notes(end+1)    = {''};
    -0261     model.ec.eccodes(end+1)  = {''};
    -0262 
    -0263     % Update the enzyme rxns matrix
    -0264     model.ec.rxnEnzMat(numRxns+i, stdMetIdx) = 1;
    -0265 end
    -0266 % Get the rxns identifiers of the updated rxns
    -0267 rxnsMissingGPR = model.rxns(rxnsMissingGPR);
    -0268 
    -0269 if fillZeroKcat
    -0270     zeroKcat = model.ec.kcat == 0 | isnan(model.ec.kcat);
    -0271     model.ec.kcat(zeroKcat)     = standardKcat;
    -0272     model.ec.source(zeroKcat)   = {'standard'};
    -0273     rxnsNoKcat = model.ec.rxns(zeroKcat);
    -0274 else
    -0275     rxnsNoKcat = [];
    -0276 end
    -0277 end
    -0278 
    -0279 function Cflat = flattenCell(C,strFlag)
    -0280 %FLATTENCELL  Flatten a nested column cell array into a matrix cell array.
    -0281 %
    -0282 % CFLAT = FLATTENCELL(C) takes a column cell array in which one or more
    -0283 % entries is a nested cell array, and flattens it into a 2D matrix cell
    -0284 % array, where the nested entries are spread across new columns.
    -0285 %
    -0286 % CFLAT = FLATTENCELL(C,STRFLAG) if STRFLAG is TRUE, empty entries in the
    -0287 % resulting CFLAT will be replaced with empty strings {''}. Default = FALSE
    -0288 if nargin < 2
    -0289     strFlag = false;
    -0290 end
    -0291 
    -0292 % determine which entries are cells
    -0293 cells = cellfun(@iscell,C);
    -0294 
    -0295 % determine number of elements in each nested cell
    -0296 cellsizes = cellfun(@numel,C);
    -0297 cellsizes(~cells) = 1;  % ignore non-cell entries
    -0298 
    -0299 % flatten single-entry cells
    -0300 Cflat = C;
    -0301 Cflat(cells & (cellsizes == 1)) = cellfun(@(x) x{1},Cflat(cells & (cellsizes == 1)),'UniformOutput',false);
    -0302 
    -0303 % iterate through multi-entry cells
    -0304 multiCells = find(cellsizes > 1);
    -0305 for i = 1:length(multiCells)
    -0306     cellContents = Cflat{multiCells(i)};
    -0307     Cflat(multiCells(i),1:length(cellContents)) = cellContents;
    -0308 end
    -0309 
    -0310 % change empty elements to strings, if specified
    -0311 if ( strFlag )
    -0312     Cflat(cellfun(@isempty,Cflat)) = {''};
    -0313 end
    -0314 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/gather_kcats/index.html b/doc/src/geckomat/gather_kcats/index.html deleted file mode 100644 index 3f5abb63..00000000 --- a/doc/src/geckomat/gather_kcats/index.html +++ /dev/null @@ -1,29 +0,0 @@ - - - - Index for Directory src\geckomat\gather_kcats - - - - - - - - - - -
    < Master indexIndex for src\geckomat\gather_kcats >
    - -

    Index for src\geckomat\gather_kcats

    - -

    Matlab files in this directory:

    - -
     fuzzyKcatMatchingfuzzyKcatMatching
     getStandardKcatgetStandardKcat
     mergeDLKcatAndFuzzyKcatsmergeDlkcatAndFuzzyKcats
     readDLKcatOutputreadDLKcatOutput
     removeStandardKcatremoveStandardKcat
     runDLKcatrunDLKcat
     selectKcatValueselectKcatValue
     writeDLKcatInputwriteDLKcatInput
    - - - - -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/gather_kcats/mergeDLKcatAndFuzzyKcats.html b/doc/src/geckomat/gather_kcats/mergeDLKcatAndFuzzyKcats.html deleted file mode 100644 index 7f9e5908..00000000 --- a/doc/src/geckomat/gather_kcats/mergeDLKcatAndFuzzyKcats.html +++ /dev/null @@ -1,199 +0,0 @@ - - - - Description of mergeDLKcatAndFuzzyKcats - - - - - - - - - -
    Home > src > geckomat > gather_kcats > mergeDLKcatAndFuzzyKcats.m
    - - - -

    mergeDLKcatAndFuzzyKcats -

    - -

    PURPOSE ^

    -
    mergeDlkcatAndFuzzyKcats
    - -

    SYNOPSIS ^

    -
    function mergedKcatList = mergeDLKcatAndFuzzyKcats(kcatListDLKcat, kcatListFuzzy, topOriginLimit, bottomOriginLimit, wildcardLimit)
    - -

    DESCRIPTION ^

    -
     mergeDlkcatAndFuzzyKcats
    -   Merges the results from DLKcat and fuzzy matching to BRENDA database.
    -   Order of preference:
    -   1: BRENDA match with correct E.C. number, with origin (see below) not
    -      lower than the specified topOriginLimit
    -   2: DLKcat match
    -   3: BRENDA match with correct E.C. number, with origin below
    -      topOriginLimit but not lower than the bottomOriginLimit
    -   4: BRENDA match with wildcards in the E.C. number, with not more
    -      wildcards than wildcardLimit, and origin not lower than the
    -      bottomOriginLimit
    -
    - Input:
    -   kcatListDLKcat      kcatList derived from readDLKcatOutput
    -   kcatListFuzzy       kcatList derived from fuzzyKcatMatching
    -   topOriginLimit      origin limit for prioritized BRENDA matches. Origin
    -                       is explained in more detail below. (Optional,
    -                       default 6)
    -   bottomOriginLimit   origin limit for low priority BRENDA matches.
    -                       Origin is explained in more detail below.
    -                       (Optional, default 6)
    -   wildcardLimit       maximum number of wildcards in E.C. number of
    -                       BRENDA matches (Optional, default 3)
    -
    - Output:
    -   mergedKcatList      merged list of kcats
    -   
    - The origin parameter:
    -   1: correct organism, correct substrate, kcat
    -   2: any organism, correct substrate, kcat
    -   3: correct organism, any substrate, kcat
    -   4: any organism, any substrate, kcat
    -   5: correct organism, specific activity
    -   6: any organism, specific activity
    -
    - Example of wildcards in E.C. number:
    -   0: 1.1.1.3      glycerol-3-phosphate dehydrogenase (NAD+)
    -   1: 1.1.1.-      oxidoreductase, acting on the CH-OH group of donors,
    -                   with NAD+ or NADP+ as acceptor
    -   2: 1.1.-.-      oxidoreductase, acting on the CH-OH group of donors
    -   3: 1.-.-.-      oxidoreductase
    -
    - Usage:
    -   mergedKcatList = mergeDLKcatAndFuzzyKcats(kcatListDLKcat, kcatListFuzzy, topOriginLimit, bottomOriginLimit, wildcardLimit)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function mergedKcatList = mergeDLKcatAndFuzzyKcats(kcatListDLKcat, kcatListFuzzy, topOriginLimit, bottomOriginLimit, wildcardLimit)
    -0002 % mergeDlkcatAndFuzzyKcats
    -0003 %   Merges the results from DLKcat and fuzzy matching to BRENDA database.
    -0004 %   Order of preference:
    -0005 %   1: BRENDA match with correct E.C. number, with origin (see below) not
    -0006 %      lower than the specified topOriginLimit
    -0007 %   2: DLKcat match
    -0008 %   3: BRENDA match with correct E.C. number, with origin below
    -0009 %      topOriginLimit but not lower than the bottomOriginLimit
    -0010 %   4: BRENDA match with wildcards in the E.C. number, with not more
    -0011 %      wildcards than wildcardLimit, and origin not lower than the
    -0012 %      bottomOriginLimit
    -0013 %
    -0014 % Input:
    -0015 %   kcatListDLKcat      kcatList derived from readDLKcatOutput
    -0016 %   kcatListFuzzy       kcatList derived from fuzzyKcatMatching
    -0017 %   topOriginLimit      origin limit for prioritized BRENDA matches. Origin
    -0018 %                       is explained in more detail below. (Optional,
    -0019 %                       default 6)
    -0020 %   bottomOriginLimit   origin limit for low priority BRENDA matches.
    -0021 %                       Origin is explained in more detail below.
    -0022 %                       (Optional, default 6)
    -0023 %   wildcardLimit       maximum number of wildcards in E.C. number of
    -0024 %                       BRENDA matches (Optional, default 3)
    -0025 %
    -0026 % Output:
    -0027 %   mergedKcatList      merged list of kcats
    -0028 %
    -0029 % The origin parameter:
    -0030 %   1: correct organism, correct substrate, kcat
    -0031 %   2: any organism, correct substrate, kcat
    -0032 %   3: correct organism, any substrate, kcat
    -0033 %   4: any organism, any substrate, kcat
    -0034 %   5: correct organism, specific activity
    -0035 %   6: any organism, specific activity
    -0036 %
    -0037 % Example of wildcards in E.C. number:
    -0038 %   0: 1.1.1.3      glycerol-3-phosphate dehydrogenase (NAD+)
    -0039 %   1: 1.1.1.-      oxidoreductase, acting on the CH-OH group of donors,
    -0040 %                   with NAD+ or NADP+ as acceptor
    -0041 %   2: 1.1.-.-      oxidoreductase, acting on the CH-OH group of donors
    -0042 %   3: 1.-.-.-      oxidoreductase
    -0043 %
    -0044 % Usage:
    -0045 %   mergedKcatList = mergeDLKcatAndFuzzyKcats(kcatListDLKcat, kcatListFuzzy, topOriginLimit, bottomOriginLimit, wildcardLimit)
    -0046 
    -0047 if nargin < 5
    -0048     wildcardLimit = 3;
    -0049 end
    -0050 
    -0051 if nargin < 4
    -0052     bottomOriginLimit = 6;
    -0053 end
    -0054 
    -0055 if nargin < 3
    -0056     topOriginLimit = 6;
    -0057 end
    -0058 
    -0059 if (topOriginLimit < 1) || (topOriginLimit > 6)
    -0060     error('topPrioOriginLimit should be between 1 and 6.');
    -0061 end
    -0062 
    -0063 if (bottomOriginLimit < 1) || (bottomOriginLimit > 6)
    -0064     error('originCutLevel should be between 1 and 6.');
    -0065 end
    -0066 
    -0067 if (wildcardLimit < 0) || (wildcardLimit > 3)
    -0068     error('wildcardCutLevel should be between 0 and 3.');
    -0069 end
    -0070 
    -0071 wc = kcatListFuzzy.wildcardLvl;
    -0072 wc(isnan(wc)) = 1000; %large wildcard
    -0073 
    -0074 origin = kcatListFuzzy.origin;
    -0075 origin(isnan(origin)) = 1000; %large origin
    -0076 
    -0077 prio1 = (wc == 0) & (origin <= topOriginLimit);
    -0078 
    -0079 rxnsWithPrio1 = unique(kcatListFuzzy.rxns(prio1));
    -0080 
    -0081 %Things get a bit complicated since not all reactions are in the kcatLists and
    -0082 %some reactions may appear multiple times
    -0083 prio2 = true(length(kcatListDLKcat.rxns),1);
    -0084 prio2(ismember(kcatListDLKcat.rxns, rxnsWithPrio1)) = false;
    -0085 prio2Rxns = unique(kcatListDLKcat.rxns(prio2));
    -0086 
    -0087 %The prioritization between wildcards and origin is already done in fuzzy matching,
    -0088 %so we can join them here
    -0089 prio3 = ((wc == 0) & (origin > topOriginLimit) & (origin <= bottomOriginLimit)) | ...
    -0090         ((wc > 0) & (wc <= wildcardLimit) & (origin <= bottomOriginLimit));
    -0091 prio3(ismember(kcatListFuzzy.rxns, prio2Rxns)) = false;
    -0092 
    -0093 fuzzyRxns = prio1 | prio3;
    -0094 
    -0095 %Now build the merged list, fuzzy followed by dlkcat
    -0096 %The order of the reactions is therefore not preserved.
    -0097 mergedKcatList               = struct();
    -0098 mergedKcatList.source        = 'Merged DLKcat and fuzzy';
    -0099 [fuzzySrc{1:sum(fuzzyRxns)}] = deal(kcatListFuzzy.source);
    -0100 [dlkcatSrc{1:sum(prio2)}]    = deal(kcatListDLKcat.source);
    -0101 mergedKcatList.kcatSource    = [fuzzySrc.';dlkcatSrc.'];
    -0102 mergedKcatList.rxns          = [kcatListFuzzy.rxns(fuzzyRxns);kcatListDLKcat.rxns(prio2)];
    -0103 mergedKcatList.genes         = [cell(sum(fuzzyRxns),1);kcatListDLKcat.genes(prio2)];
    -0104 mergedKcatList.substrates    = [kcatListFuzzy.substrates(fuzzyRxns);kcatListDLKcat.substrates(prio2)];
    -0105 mergedKcatList.kcats         = [kcatListFuzzy.kcats(fuzzyRxns);kcatListDLKcat.kcats(prio2)];
    -0106 mergedKcatList.eccodes       = [kcatListFuzzy.eccodes(fuzzyRxns);cell(sum(prio2),1)];
    -0107 mergedKcatList.wildcardLvl   = [kcatListFuzzy.wildcardLvl(fuzzyRxns);nan(sum(prio2),1)];
    -0108 mergedKcatList.origin        = [kcatListFuzzy.origin(fuzzyRxns);nan(sum(prio2),1)];
    -0109 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/gather_kcats/readDLKcatOutput.html b/doc/src/geckomat/gather_kcats/readDLKcatOutput.html deleted file mode 100644 index cb45963f..00000000 --- a/doc/src/geckomat/gather_kcats/readDLKcatOutput.html +++ /dev/null @@ -1,148 +0,0 @@ - - - - Description of readDLKcatOutput - - - - - - - - - -
    Home > src > geckomat > gather_kcats > readDLKcatOutput.m
    - - - -

    readDLKcatOutput -

    - -

    PURPOSE ^

    -
    readDLKcatOutput
    - -

    SYNOPSIS ^

    -
    function kcatList = readDLKcatOutput(model, outFile, modelAdapter)
    - -

    DESCRIPTION ^

    -
     readDLKcatOutput
    -   Reads the DLKcat output file and constructs a kcatList structure, that
    -   can be used by selectKcatValue() to populate the ecModel with kcat
    -   values.
    -
    - Input:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   outFile         name and path of the DLKcat output file. (Optional,
    -                   default is data/DLKcat.tsv from the obj.params.path
    -                   folder specified in the modelAdapter)
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -                   default model adapter).
    -
    - Output:
    -   kcatList    structure array with list of DLKcat derived kcat values,
    -               with separate entries for each kcat value
    -               source      'DLKcat'           
    -               rxns        reaction identifiers
    -               genes       gene identifiers
    -               substrate   substrate names
    -               kcat        predicted kcat value in /sec
    -
    - Usage:
    -   kcatList = readDLKcatOutput(model, outFile, modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function kcatList = readDLKcatOutput(model, outFile, modelAdapter)
    -0002 % readDLKcatOutput
    -0003 %   Reads the DLKcat output file and constructs a kcatList structure, that
    -0004 %   can be used by selectKcatValue() to populate the ecModel with kcat
    -0005 %   values.
    -0006 %
    -0007 % Input:
    -0008 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0009 %   outFile         name and path of the DLKcat output file. (Optional,
    -0010 %                   default is data/DLKcat.tsv from the obj.params.path
    -0011 %                   folder specified in the modelAdapter)
    -0012 %   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -0013 %                   default model adapter).
    -0014 %
    -0015 % Output:
    -0016 %   kcatList    structure array with list of DLKcat derived kcat values,
    -0017 %               with separate entries for each kcat value
    -0018 %               source      'DLKcat'
    -0019 %               rxns        reaction identifiers
    -0020 %               genes       gene identifiers
    -0021 %               substrate   substrate names
    -0022 %               kcat        predicted kcat value in /sec
    -0023 %
    -0024 % Usage:
    -0025 %   kcatList = readDLKcatOutput(model, outFile, modelAdapter)
    -0026 
    -0027 if nargin < 3 || isempty(modelAdapter)
    -0028     modelAdapter = ModelAdapterManager.getDefault();
    -0029     if isempty(modelAdapter)
    -0030         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0031     end
    -0032 end
    -0033 params = modelAdapter.params;
    -0034 
    -0035 if nargin<2 || isempty(outFile)
    -0036     fID      = fopen(fullfile(params.path,'data','DLKcat.tsv'),'r');
    -0037 else
    -0038     fID      = fopen(outFile);
    -0039 end
    -0040 DLKcatOutput = textscan(fID,'%s %s %s %s %s %s','Delimiter','\t','HeaderLines',1);
    -0041 fclose(fID);
    -0042 
    -0043 % Check that DLKcat output file and model match (not fool proof, but good enough)
    -0044 [rxns, genes, subs, kcats] = deal(DLKcatOutput{[1,2,3,6]});
    -0045 
    -0046 % Check if it contains any kcat values
    -0047 if all(cellfun(@isempty,kcats)) || all(strcmpi(kcats,'NA'))
    -0048     error('DLKcat file does not contain any kcat values, please run runDLKcat() first.')
    -0049 end
    -0050 
    -0051 % Check that all substrates are in the model
    -0052 matchMets = ismember(subs,model.metNames);
    -0053 if ~all(matchMets)
    -0054     errorText = 'DLKcat was likely run with an input file that was generated from another ecModel, as the following substrates from DLKcat output cannot be found in model.metNames:';
    -0055     dispEM(errorText,true,subs(~matchMets),false)
    -0056 end
    -0057 
    -0058 % Check that all reactions are in model.ec.rxns
    -0059 matchRxns = ismember(rxns,model.ec.rxns);
    -0060 if ~all(matchRxns)
    -0061     errorText = 'DLKcat was likely run with an input file that was generated from another ecModel, as the following reactions from DLKcat output cannot be found in model.metNames:';
    -0062     dispEM(errorText,true,rxns(~matchRxns),false)
    -0063 end
    -0064 
    -0065 % Filter out entries with no numeric value
    -0066 noOutput        = cellfun(@isempty,regexpi(kcats,'[0-9]'));
    -0067 kcats           = str2double(kcats(~noOutput));
    -0068 rxns(noOutput)  = [];
    -0069 genes(noOutput) = [];
    -0070 subs(noOutput)  = [];
    -0071 
    -0072 % Make kcatList structure
    -0073 kcatList.source     = 'DLKcat';
    -0074 kcatList.rxns       = rxns;
    -0075 kcatList.genes      = genes;
    -0076 kcatList.substrates = subs;
    -0077 kcatList.kcats      = kcats;
    -0078 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/gather_kcats/removeStandardKcat.html b/doc/src/geckomat/gather_kcats/removeStandardKcat.html deleted file mode 100644 index 66f03c33..00000000 --- a/doc/src/geckomat/gather_kcats/removeStandardKcat.html +++ /dev/null @@ -1,127 +0,0 @@ - - - - Description of removeStandardKcat - - - - - - - - - -
    Home > src > geckomat > gather_kcats > removeStandardKcat.m
    - - - -

    removeStandardKcat -

    - -

    PURPOSE ^

    -
    removeStandardKcat
    - -

    SYNOPSIS ^

    -
    function model = removeStandardKcat(model)
    - -

    DESCRIPTION ^

    -
     removeStandardKcat
    -   Remove the "standard" pseudoenzyme and standard kcat and MW values, as
    -   they were introduced by getStandardKcat. Also standard kcat values that
    -   were assigned by getStandardKcat if fillZeroKcat was set to true are
    -   removed from model.ec.kcat. Both the model.ec and model.S structures
    -   are modified.
    -
    - Input:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -                   that has standard kcat values implemented by
    -                   getStandardKcat.
    -
    - Output:
    -   model           ecModel without standard pseudoprotein and standard
    -                   kcat values
    -
    - Usage:
    -    model = removeStandardKcat(model);
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function model = removeStandardKcat(model)
    -0002 % removeStandardKcat
    -0003 %   Remove the "standard" pseudoenzyme and standard kcat and MW values, as
    -0004 %   they were introduced by getStandardKcat. Also standard kcat values that
    -0005 %   were assigned by getStandardKcat if fillZeroKcat was set to true are
    -0006 %   removed from model.ec.kcat. Both the model.ec and model.S structures
    -0007 %   are modified.
    -0008 %
    -0009 % Input:
    -0010 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0011 %                   that has standard kcat values implemented by
    -0012 %                   getStandardKcat.
    -0013 %
    -0014 % Output:
    -0015 %   model           ecModel without standard pseudoprotein and standard
    -0016 %                   kcat values
    -0017 %
    -0018 % Usage:
    -0019 %    model = removeStandardKcat(model);
    -0020 
    -0021 % Remove standard enzyme from ec structure
    -0022 stdEnzIdx = find(strcmpi(model.ec.enzymes, 'standard'));
    -0023 if ~isempty(stdEnzIdx)
    -0024     model.ec.genes(stdEnzIdx)       = [];
    -0025     model.ec.enzymes(stdEnzIdx)     = [];
    -0026     model.ec.mw(stdEnzIdx)          = [];
    -0027     model.ec.sequence(stdEnzIdx)    = [];
    -0028     if isfield(model.ec,'concs')
    -0029         model.ec.concs(stdEnzIdx)   = [];
    -0030     end
    -0031     rxnEnzIdx = find(model.ec.rxnEnzMat(:,stdEnzIdx));
    -0032     model.ec.rxns(rxnEnzIdx)        = [];
    -0033     model.ec.kcat(rxnEnzIdx)        = [];
    -0034     model.ec.source(rxnEnzIdx)      = [];
    -0035     model.ec.notes(rxnEnzIdx)       = [];
    -0036     model.ec.eccodes(rxnEnzIdx)     = [];
    -0037     model.ec.rxnEnzMat(:,stdEnzIdx) = [];
    -0038     model.ec.rxnEnzMat(rxnEnzIdx,:) = [];
    -0039 end
    -0040 
    -0041 % Remove standard kcat values and reapply kcat constraints for those
    -0042 % specific reactions
    -0043 stdKcatIdx = find(strcmpi(model.ec.source, 'standard'));
    -0044 if ~isempty(stdKcatIdx)
    -0045     model.ec.source(stdKcatIdx)     = {''};
    -0046     model.ec.kcat(stdKcatIdx)       = 0;
    -0047     model = applyKcatConstraints(model,stdKcatIdx);
    -0048 end
    -0049 
    -0050 % Remove standard protein, usage and gene from model structure
    -0051 stdMetIdx = find(strcmpi(model.mets, 'prot_standard'));
    -0052 if ~isempty(stdMetIdx)
    -0053     model       = removeMets(model,stdMetIdx,false,false,false,false);
    -0054 end
    -0055 stdProtEx = find(strcmpi(model.rxns, 'usage_prot_standard'));
    -0056 if ~isempty(stdProtEx)
    -0057     model       = removeReactions(model,stdProtEx,false,false,false);
    -0058 end
    -0059 stdProtGene = find(strcmpi(model.genes, 'standard'));
    -0060 if ~isempty(stdProtGene)
    -0061     model       = removeGenes(model,stdProtGene,false,false,false);
    -0062 end
    -0063 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/gather_kcats/runDLKcat.html b/doc/src/geckomat/gather_kcats/runDLKcat.html deleted file mode 100644 index 313f2fbe..00000000 --- a/doc/src/geckomat/gather_kcats/runDLKcat.html +++ /dev/null @@ -1,121 +0,0 @@ - - - - Description of runDLKcat - - - - - - - - - -
    Home > src > geckomat > gather_kcats > runDLKcat.m
    - - - -

    runDLKcat -

    - -

    PURPOSE ^

    -
    runDLKcat
    - -

    SYNOPSIS ^

    -
    function runDLKcat(modelAdapter,filePath)
    - -

    DESCRIPTION ^

    -
     runDLKcat
    -   Runs DLKcat to predict kcat values from a Docker image. Once DLKcat is succesfully
    -   run, the DLKcatFile will be overwritten with the DLKcat
    -   output in the model-specific 'data' sub-folder taken from modelAdapter
    -   (e.g. GECKO/tutorials/tutorial_yeast-GEM/data/DLKcat.tsv)
    -
    - Input
    -   modelAdapter    a loaded model adapter. (Optional, will otherwise use
    -                   the default model adapter)
    -   filePath        path to the DLKcat.tsv file. (Optional, will otherwise
    -                   assume data/DLKcat.tsv)
    -
    -   NOTE: 1. Requires Docker to be installed, and Docker Desktop running. Visit "https://www.docker.com"
    -         2. Runtime will depend on whether the image is to be downloaded or not.
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function runDLKcat(modelAdapter,filePath)
    -0002 % runDLKcat
    -0003 %   Runs DLKcat to predict kcat values from a Docker image. Once DLKcat is succesfully
    -0004 %   run, the DLKcatFile will be overwritten with the DLKcat
    -0005 %   output in the model-specific 'data' sub-folder taken from modelAdapter
    -0006 %   (e.g. GECKO/tutorials/tutorial_yeast-GEM/data/DLKcat.tsv)
    -0007 %
    -0008 % Input
    -0009 %   modelAdapter    a loaded model adapter. (Optional, will otherwise use
    -0010 %                   the default model adapter)
    -0011 %   filePath        path to the DLKcat.tsv file. (Optional, will otherwise
    -0012 %                   assume data/DLKcat.tsv)
    -0013 %
    -0014 %   NOTE: 1. Requires Docker to be installed, and Docker Desktop running. Visit "https://www.docker.com"
    -0015 %         2. Runtime will depend on whether the image is to be downloaded or not.
    -0016 
    -0017 if nargin < 1 || isempty(modelAdapter)
    -0018     modelAdapter = ModelAdapterManager.getDefault();
    -0019     if isempty(modelAdapter)
    -0020         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0021     end
    -0022 end
    -0023 params = modelAdapter.params;
    -0024 % Make sure path is full, not relative
    -0025 [~, params.path] = fileattrib(params.path);
    -0026 params.path=params.path.Name;
    -0027 
    -0028 if nargin < 2 || isempty(filePath)
    -0029     filePath = fullfile(params.path,'data','DLKcat.tsv');
    -0030 elseif strcmp(filePath(end),{'\','/'})
    -0031     filePath = fullfile(filePath,'DLKcat.tsv');
    -0032 end
    -0033 filePath = checkFileExistence(filePath,1);
    -0034 
    -0035 copyfile(filePath, fullfile(params.path,'data','tempDLKcat.tsv'));
    -0036     
    -0037 
    -0038 %% Check and install requirements
    -0039 % On macOS, Docker might not be properly loaded if MATLAB is started via
    -0040 % launcher and not terminal.
    -0041 if ismac
    -0042     setenv('PATH', strcat('/usr/local/bin', ':', getenv("PATH")));
    -0043 end
    -0044 
    -0045 % Check if Docker is installed
    -0046 [checks.docker.status, checks.docker.out] = system('docker --version');
    -0047 if checks.docker.status ~= 0
    -0048     error('Cannot find Docker, make sure it is installed. If it is, it might be required to start Matlab from the command-line instead of the launcher in order for Docker to be detected and used.')
    -0049 end
    -0050 
    -0051 disp('Running DLKcat prediction, this may take many minutes, especially the first time.')
    -0052 status = system(['docker run --rm -v "' fullfile(params.path,'/data') '":/data ghcr.io/sysbiochalmers/dlkcat-gecko:0.1 /bin/bash -c "python DLKcat.py /data/tempDLKcat.tsv /data/tempDLKcatOutput.tsv"']);
    -0053 delete(fullfile(params.path,'/data/tempDLKcat.tsv'));
    -0054 
    -0055 if status == 0 && exist(fullfile(params.path,'data/tempDLKcatOutput.tsv'))
    -0056     movefile(fullfile(params.path,'/data/tempDLKcatOutput.tsv'), filePath);
    -0057     disp('DKLcat prediction completed.');
    -0058 else    
    -0059     error('DLKcat encountered an error or it did not create any output file.')
    -0060 end
    -0061
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/gather_kcats/selectKcatValue.html b/doc/src/geckomat/gather_kcats/selectKcatValue.html deleted file mode 100644 index f82c61fc..00000000 --- a/doc/src/geckomat/gather_kcats/selectKcatValue.html +++ /dev/null @@ -1,181 +0,0 @@ - - - - Description of selectKcatValue - - - - - - - - - -
    Home > src > geckomat > gather_kcats > selectKcatValue.m
    - - - -

    selectKcatValue -

    - -

    PURPOSE ^

    -
    selectKcatValue
    - -

    SYNOPSIS ^

    -
    function [model, rxnIdx] = selectKcatValue(model,kcatList,criteria,overwrite)
    - -

    DESCRIPTION ^

    -
     selectKcatValue
    -   From a kcatList with predicted or suggested kcat values, where each
    -   reaction may have multiple entries, one kcat value is selected and
    -   written to model.ec.kcat. Zero values are discarded from the start. By
    -   default, the maximum value is chosen, but alternatives are available.
    -   The kcatList structure is an output of e.g. readDLKcatOutput,
    -   readGotEnzymesOutput, readManualKcatList.
    -
    - Input:
    -   model       an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   kcatList    structure array with separate entries for each kcat value
    -               source      e.g. 'DLKcat' or 'gotenzymes'           
    -               rxns        reaction identifiers, matching model.rxns
    -               genes       gene identifiers, matching model.genes
    -               substrate   substrates, matching model.mets
    -               kcat        predicted kcat value in /sec
    -   criteria    which kcat value should be selected if multiple values are
    -               provided. Options: 'max', 'min', 'median', 'mean'. (Opt,
    -               default 'max')
    -   overwrite   whether existing kcat values should be overwritten.
    -               Options: 'true', 'false', 'ifHigher'. The last option will
    -               overwrite only if the new kcat value is higher. (Opt,
    -               default 'true')
    -
    - Output:
    -   model       ecModel with updated model.ec.kcat and model.ec.source
    -   rxnIdx      list of reaction indices (matching model.ec.rxns), to
    -               indicate which kcat values have been changed.
    - Usage:
    -   [model, rxnIdx] = selectKcatValue(model,kcatList,criteria,overwrite)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function [model, rxnIdx] = selectKcatValue(model,kcatList,criteria,overwrite)
    -0002 % selectKcatValue
    -0003 %   From a kcatList with predicted or suggested kcat values, where each
    -0004 %   reaction may have multiple entries, one kcat value is selected and
    -0005 %   written to model.ec.kcat. Zero values are discarded from the start. By
    -0006 %   default, the maximum value is chosen, but alternatives are available.
    -0007 %   The kcatList structure is an output of e.g. readDLKcatOutput,
    -0008 %   readGotEnzymesOutput, readManualKcatList.
    -0009 %
    -0010 % Input:
    -0011 %   model       an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0012 %   kcatList    structure array with separate entries for each kcat value
    -0013 %               source      e.g. 'DLKcat' or 'gotenzymes'
    -0014 %               rxns        reaction identifiers, matching model.rxns
    -0015 %               genes       gene identifiers, matching model.genes
    -0016 %               substrate   substrates, matching model.mets
    -0017 %               kcat        predicted kcat value in /sec
    -0018 %   criteria    which kcat value should be selected if multiple values are
    -0019 %               provided. Options: 'max', 'min', 'median', 'mean'. (Opt,
    -0020 %               default 'max')
    -0021 %   overwrite   whether existing kcat values should be overwritten.
    -0022 %               Options: 'true', 'false', 'ifHigher'. The last option will
    -0023 %               overwrite only if the new kcat value is higher. (Opt,
    -0024 %               default 'true')
    -0025 %
    -0026 % Output:
    -0027 %   model       ecModel with updated model.ec.kcat and model.ec.source
    -0028 %   rxnIdx      list of reaction indices (matching model.ec.rxns), to
    -0029 %               indicate which kcat values have been changed.
    -0030 % Usage:
    -0031 %   [model, rxnIdx] = selectKcatValue(model,kcatList,criteria,overwrite)
    -0032 
    -0033 if nargin < 4
    -0034     overwrite = 'true';
    -0035 elseif islogical(overwrite)
    -0036     if overwrite
    -0037         overwrite = 'true';
    -0038     else
    -0039         overwrite = 'false';
    -0040     end
    -0041 end
    -0042 if nargin < 3
    -0043     criteria = 'max';
    -0044 end
    -0045 
    -0046 % Remove zero kcat values. Only adjusting fields that are used later.
    -0047 removeZero                      = kcatList.kcats == 0;
    -0048 kcatList.kcats(removeZero)      = [];
    -0049 kcatList.rxns(removeZero)       = [];
    -0050 
    -0051 % Map to model.ec.rxns
    -0052 [sanityCheck,idxInModel] = ismember(kcatList.rxns,model.ec.rxns);
    -0053 if ~all(sanityCheck)
    -0054     error('Not all reactions in kcatList are found in model.ec.rxns')
    -0055 end
    -0056 % Make vector with single kcat value per reaction
    -0057 idxInModelUnique = unique(idxInModel);
    -0058 selectedKcats    = zeros(numel(idxInModelUnique),1);
    -0059 selectedSource   = cell(numel(selectedKcats),1);
    -0060 if ~isfield(kcatList,'kcatSource')
    -0061     kcatList.kcatSource = cell(numel(kcatList.kcats),1);
    -0062     kcatList.kcatSource(:) = {kcatList.source};
    -0063 end
    -0064 for i=1:numel(idxInModelUnique)
    -0065     ind = idxInModelUnique(i);
    -0066     idxMatch = find(idxInModel == ind);
    -0067     % Choose the maximum number
    -0068     switch criteria
    -0069         case 'max'
    -0070             [selectedKcats(i),j] = max(kcatList.kcats(idxMatch));
    -0071         case 'min'
    -0072             [selectedKcats(i),j] = min(kcatList.kcats(idxMatch));
    -0073         case 'median'
    -0074             [selectedKcats(i),j] = median(kcatList.kcats(idxMatch));
    -0075         case 'mean'
    -0076             [selectedKcats(i),j] = mean(kcatList.kcats(idxMatch));
    -0077         otherwise
    -0078             error('Invalid criteria specified')
    -0079     end
    -0080     selectedSource(i)    = kcatList.kcatSource(idxMatch(j));
    -0081 end
    -0082 
    -0083 % Populate model.ec.kcat
    -0084 switch overwrite
    -0085     case 'true'
    -0086         model.ec.kcat(idxInModelUnique) = selectedKcats;
    -0087         model.ec.source(idxInModelUnique) = selectedSource;
    -0088     case 'false'
    -0089         emptyKcats = find(model.ec.kcat == 0);
    -0090         [idxInModelUnique,whickKcats] = intersect(idxInModelUnique,emptyKcats,'stable');
    -0091         model.ec.kcat(idxInModelUnique) = selectedKcats(whickKcats);
    -0092         model.ec.source(idxInModelUnique) = selectedSource(whickKcats);
    -0093         
    -0094     case 'ifHigher'
    -0095         higherKcats = model.ec.kcat(idxInModelUnique) < selectedKcats;
    -0096         selectedKcats(~higherKcats) = [];
    -0097         selectedSource(~higherKcats) = [];
    -0098         idxInModelUnique(~higherKcats) = [];
    -0099         model.ec.kcat(idxInModelUnique) = selectedKcats;
    -0100         model.ec.source(idxInModelUnique) = selectedSource;
    -0101     otherwise
    -0102         error('Invalid overwrite flag specified')
    -0103 end
    -0104 rxnIdx = idxInModelUnique;
    -0105 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/gather_kcats/writeDLKcatInput.html b/doc/src/geckomat/gather_kcats/writeDLKcatInput.html deleted file mode 100644 index b8a1b4ae..00000000 --- a/doc/src/geckomat/gather_kcats/writeDLKcatInput.html +++ /dev/null @@ -1,237 +0,0 @@ - - - - Description of writeDLKcatInput - - - - - - - - - -
    Home > src > geckomat > gather_kcats > writeDLKcatInput.m
    - - - -

    writeDLKcatInput -

    - -

    PURPOSE ^

    -
    writeDLKcatInput
    - -

    SYNOPSIS ^

    -
    function writtenTable = writeDLKcatInput(model, ecRxns, modelAdapter, onlyWithSmiles, filename, overwrite)
    - -

    DESCRIPTION ^

    -
     writeDLKcatInput
    -   Prepares the input for DLKcat, and writes it to data/DLKcat.tsv
    -   in the obj.params.path specified in the ModelAdapter.
    -
    - Input:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   ecRxns          for which reactions (from model.ec.rxns) DLKcat should
    -                   predict kcat values, provided as logical vector with
    -                   same length as model.ec.rxns. (Opt, default is all
    -                   reactions)
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -                   default model adapter).
    -   onlyWithSmiles  logical whether to only include metabolites with SMILES
    -                   (optional, default true)
    -   filename        path to the input file, including the filename and .tsv
    -                   extension (Optional, default is data/DLKcat.tsv from
    -                   the obj.params.path folder specified in the modelAdapter)
    -   overwrite       logical whether existing file should be overwritten.
    -                   (Optional, default false, to prevent overwriting file
    -                   that already contains DLKcat-predicted kcat values).
    -
    - Output:
    -   writtenTable    The table written, mainly to be used for testing purposes.
    -
    - Usage:
    -   writtenTable = writeDLKcatInput(model, ecRxns, modelAdapter, onlyWithSmiles, filename, overwrite)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function writtenTable = writeDLKcatInput(model, ecRxns, modelAdapter, onlyWithSmiles, filename, overwrite)
    -0002 % writeDLKcatInput
    -0003 %   Prepares the input for DLKcat, and writes it to data/DLKcat.tsv
    -0004 %   in the obj.params.path specified in the ModelAdapter.
    -0005 %
    -0006 % Input:
    -0007 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0008 %   ecRxns          for which reactions (from model.ec.rxns) DLKcat should
    -0009 %                   predict kcat values, provided as logical vector with
    -0010 %                   same length as model.ec.rxns. (Opt, default is all
    -0011 %                   reactions)
    -0012 %   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -0013 %                   default model adapter).
    -0014 %   onlyWithSmiles  logical whether to only include metabolites with SMILES
    -0015 %                   (optional, default true)
    -0016 %   filename        path to the input file, including the filename and .tsv
    -0017 %                   extension (Optional, default is data/DLKcat.tsv from
    -0018 %                   the obj.params.path folder specified in the modelAdapter)
    -0019 %   overwrite       logical whether existing file should be overwritten.
    -0020 %                   (Optional, default false, to prevent overwriting file
    -0021 %                   that already contains DLKcat-predicted kcat values).
    -0022 %
    -0023 % Output:
    -0024 %   writtenTable    The table written, mainly to be used for testing purposes.
    -0025 %
    -0026 % Usage:
    -0027 %   writtenTable = writeDLKcatInput(model, ecRxns, modelAdapter, onlyWithSmiles, filename, overwrite)
    -0028 
    -0029 [geckoPath, ~] = findGECKOroot();
    -0030 
    -0031 if nargin<2 || isempty(ecRxns)
    -0032     ecRxns = true(numel(model.ec.rxns),1);
    -0033 elseif ~logical(ecRxns)
    -0034     error('ecRxns should be provided as logical vector')
    -0035 elseif numel(ecRxns)~=numel(model.ec.rxns)
    -0036     error('Length of ecRxns is not the same as model.ec.rxns')
    -0037 end
    -0038 ecRxns = find(ecRxns); % Change to indices
    -0039 
    -0040 if nargin < 3 || isempty(modelAdapter)
    -0041     modelAdapter = ModelAdapterManager.getDefault();
    -0042     if isempty(modelAdapter)
    -0043         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0044     end
    -0045 end
    -0046 params = modelAdapter.params;
    -0047 
    -0048 if nargin<4 || isempty(onlyWithSmiles)
    -0049     onlyWithSmiles=true;
    -0050 end
    -0051 
    -0052 if nargin<5 || isempty(filename)
    -0053     filename = fullfile(params.path,'data','DLKcat.tsv');
    -0054 elseif ~endsWith(filename,'.tsv')
    -0055     error('If filename is provided, it should include the .tsv extension.')
    -0056 end
    -0057 
    -0058 if nargin<6 || isempty(overwrite) || ~overwrite % If is true
    -0059     if exist(filename,'file')
    -0060         error([filename ' already exists, either delete it first, or set the overwrite input argument as true'])
    -0061     end
    -0062 end
    -0063 
    -0064 if ~model.ec.geckoLight
    -0065    origRxns = model.ec.rxns;
    -0066 else
    -0067    origRxns = extractAfter(model.ec.rxns,4);
    -0068 end
    -0069 origRxnsToInclude = origRxns(ecRxns);
    -0070 
    -0071 % Map back to original reactions, to extract substrates
    -0072 [sanityCheck,origRxnIdxs] = ismember(origRxnsToInclude,model.rxns);
    -0073 if ~all(sanityCheck)
    -0074     error('Not all reactions in model.ec.rxns are found in model.rxns')
    -0075 end
    -0076 
    -0077 % Ignore selected metabolites (metal ions, proteins etc.). First check by
    -0078 % name (case insensitive, without white spaces and special characters),
    -0079 % then also try to match with metSmiles (if available).
    -0080 metsNoSpecialChars = lower(regexprep(model.metNames,'[^0-9a-zA-Z]+',''));
    -0081 if exist(fullfile(params.path,'data','DLKcatIgnoreMets.tsv'),'file')
    -0082     fID        = fopen(fullfile(params.path,'data','DLKcatIgnoreMets.tsv'));
    -0083 else
    -0084     fID        = fopen(fullfile(geckoPath,'databases','DLKcatIgnoreMets.tsv'));
    -0085 end
    -0086 fileData   = textscan(fID,'%s %s','delimiter','\t');
    -0087 fclose(fID);
    -0088 [ignoreMets, ignoreSmiles] = deal(fileData{[1,2]});
    -0089 ignoreMets = lower(regexprep(ignoreMets,'[^0-9a-zA-Z]+',''));
    -0090 ignoreSmiles(cellfun(@isempty,ignoreSmiles)) = [];
    -0091 
    -0092 ignoreMetsIdx  = logical(ismember(metsNoSpecialChars,ignoreMets));
    -0093 if isfield(model,'metSmiles')
    -0094     ignoreMetsIdx = ignoreMetsIdx | logical(ismember(model.metSmiles,ignoreSmiles));
    -0095 end
    -0096 % Also leave out protein-usage pseudometabolites
    -0097 ignoreMetsIdx = ignoreMetsIdx | startsWith(model.mets,'prot_');
    -0098 reducedS = model.S;
    -0099 reducedS(ignoreMetsIdx,:) = 0;
    -0100 
    -0101 % Ignore currency metabolites if they occur in pairs. First check by
    -0102 % name (case insensitive, without white spaces and special characters),
    -0103 % then also try to match with metSmiles (if available).
    -0104 if exist(fullfile(params.path,'data','DLKcatCurrencyMets.tsv'),'file')
    -0105     fID = fopen(fullfile(params.path,'data','DLKcatCurrencyMets.tsv'));
    -0106 else
    -0107     fID = fopen(fullfile(geckoPath,'databases','DLKcatCurrencyMets.tsv'));
    -0108 end
    -0109 fileData = textscan(fID,'%s %s','delimiter','\t');
    -0110 fclose(fID);
    -0111 [currencyMets(:,1), currencyMets(:,2)] = deal(fileData{[1,2]});
    -0112 currencyMets = lower(regexprep(currencyMets,'[^0-9a-zA-Z]+',''));
    -0113 
    -0114 for i=1:size(currencyMets,1)
    -0115     subs = strcmp(currencyMets(i,1),metsNoSpecialChars);
    -0116     prod = strcmp(currencyMets(i,2),metsNoSpecialChars);
    -0117     [~,subsRxns]=find(reducedS(subs,:));
    -0118     [~,prodRxns]=find(reducedS(prod,:));
    -0119     pairRxns = intersect(subsRxns,prodRxns);
    -0120     tempRedS=reducedS;
    -0121     tempRedS([find(subs);find(prod)],pairRxns) = 0;
    -0122     % Do not remove currency mets if no substrate remains
    -0123     rxnsWithRemainingSubstrates = any(tempRedS(:,pairRxns) < 0,1);
    -0124     reducedS([find(subs);find(prod)],intersect(pairRxns,pairRxns(rxnsWithRemainingSubstrates))) = 0;
    -0125 end
    -0126 
    -0127 %filter out the reactions we're not interested in - will solve the problem for both full and light
    -0128 clearedRedS = reducedS(:,origRxnIdxs);
    -0129 rxnsToClear = true(length(origRxnIdxs),1);
    -0130 rxnsToClear(ecRxns) = false;
    -0131 clearedRedS(:,rxnsToClear) = 0;
    -0132 
    -0133 % Enumerate all substrates for each reaction
    -0134 [substrates, reactions] = find(clearedRedS<0); %the reactions here are in model.ec.rxns space
    -0135 
    -0136 % Enumerate all proteins for each reaction
    -0137 [proteins, ecRxns] = find(transpose(model.ec.rxnEnzMat(reactions,:)));
    -0138 
    -0139 % Prepare output
    -0140 out(1,:) = model.ec.rxns(reactions(ecRxns));
    -0141 out(2,:) = model.ec.genes(proteins);
    -0142 out(3,:) = model.metNames(substrates(ecRxns));
    -0143 if isfield(model,'metSmiles')
    -0144     out(4,:) = model.metSmiles(substrates(ecRxns));
    -0145 else
    -0146     out(4,:) = cell(numel(substrates(ecRxns)),1);
    -0147 end
    -0148 
    -0149 out(5,:) = model.ec.sequence(proteins);
    -0150 if onlyWithSmiles
    -0151     out(:,cellfun(@isempty,out(4,:))) = [];
    -0152 else
    -0153     out(4,cellfun(@isempty,out(4,:))) = {'None'};
    -0154 end
    -0155 out(6,:) = cell(numel(out(1,:)),1);
    -0156 out(6,:) = {'NA'};
    -0157 
    -0158 % Write file
    -0159 fID = fopen(filename,'w');
    -0160 fprintf(fID,'%s\t%s\t%s\t%s\t%s\t%s\n',out{:});
    -0161 fclose(fID);
    -0162 fprintf('Model-specific DLKcat input stored at %s\n',filename);
    -0163 
    -0164 writtenTable = out;
    -0165 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/get_enzyme_data/calculateMW.html b/doc/src/geckomat/get_enzyme_data/calculateMW.html deleted file mode 100644 index f3dc7b8a..00000000 --- a/doc/src/geckomat/get_enzyme_data/calculateMW.html +++ /dev/null @@ -1,111 +0,0 @@ - - - - Description of calculateMW - - - - - - - - - -
    Home > src > geckomat > get_enzyme_data > calculateMW.m
    - - - -

    calculateMW -

    - -

    PURPOSE ^

    -
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    - -

    SYNOPSIS ^

    -
    function MW = calculateMW(sequence)
    - -

    DESCRIPTION ^

    -
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    - MW = calculateMW(sequence)
    - Calculates de molecular weight of a protein.
    - 
    - INPUT: Sequence (can include extra things such as spaces or numbers).
    - OUTPUT: Molecular weight number
    - 
    - Benjamín Sánchez. Last edited: 2015-04-13
    -%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: - - - - - -

    SOURCE CODE ^

    -
    0001 
    -0002 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0003 % MW = calculateMW(sequence)
    -0004 % Calculates de molecular weight of a protein.
    -0005 %
    -0006 % INPUT: Sequence (can include extra things such as spaces or numbers).
    -0007 % OUTPUT: Molecular weight number
    -0008 %
    -0009 % Benjamín Sánchez. Last edited: 2015-04-13
    -0010 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0011 
    -0012 function MW = calculateMW(sequence)
    -0013 
    -0014 % A    Alanine
    -0015 % B    Aspartic acid or Asparagine
    -0016 % C    Cysteine
    -0017 % D    Aspartic acid
    -0018 % E    Glutamic acid
    -0019 % F    Phenylalanine
    -0020 % G    Glycine
    -0021 % H    Histidine
    -0022 % I    Isoleucine
    -0023 % J    Leucine or Isoleucine
    -0024 % K    Lysine
    -0025 % L    Leucine
    -0026 % M    Methionine
    -0027 % N    Asparagine
    -0028 % O    Pyrrolysine
    -0029 % P    Proline
    -0030 % Q    Glutamine
    -0031 % R    Arginine
    -0032 % S    Serine
    -0033 % T    Threonine
    -0034 % U    Selenocysteine
    -0035 % V    Valine
    -0036 % W    Tryptophan
    -0037 % X    any
    -0038 % Y    Tyrosine
    -0039 % Z    Glutamic acid or Glutamine
    -0040 
    -0041 aa_codes = {'A','B','C','D','E','F','G','H','I','J','K','L','M','N', ...
    -0042             'O','P','Q','R','S','T','U','V','W','X','Y','Z'};
    -0043 aa_MWs   = [71.08 114.60 103.14 115.09 129.11 147.17 57.05 137.14 ...
    -0044             113.16 113.16 128.17 113.16 131.20 114.10 255.31 97.12 ...
    -0045             128.13 156.19 87.08 101.10 150.04 99.13 186.21 126.50 ...
    -0046             163.17 128.62];
    -0047 
    -0048 MW = 18;
    -0049 for i = 1:length(aa_codes)
    -0050     count = length(strfind(sequence,aa_codes{i}));
    -0051     MW = MW + count*aa_MWs(i);
    -0052 end
    -0053 
    -0054 end
    -0055 
    -0056 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/get_enzyme_data/copyECtoGEM.html b/doc/src/geckomat/get_enzyme_data/copyECtoGEM.html deleted file mode 100644 index fdaae97f..00000000 --- a/doc/src/geckomat/get_enzyme_data/copyECtoGEM.html +++ /dev/null @@ -1,98 +0,0 @@ - - - - Description of copyECtoGEM - - - - - - - - - -
    Home > src > geckomat > get_enzyme_data > copyECtoGEM.m
    - - - -

    copyECtoGEM -

    - -

    PURPOSE ^

    -
    copyECtoGEM
    - -

    SYNOPSIS ^

    -
    function ecModel = copyECtoGEM(ecModel, overwrite)
    - -

    DESCRIPTION ^

    -
     copyECtoGEM
    -   Copies EC numbers from ecModel.ec.eccodes to ecModel.eccodes.
    -
    - Input:
    -   ecModel     an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   overwrite   logical that specifies if existing (non-empty) 
    -               ecModel.eccodes entries should be overwritten. Empty
    -               ecModel.eccodes entries are always overwritten if possible.
    -               default false.
    -
    - Output:
    -   ecModel     ecModel with populated model.eccodes
    -
    - Usage:
    -   ecModel = getECfromGEM(ecModel, overwrite)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function ecModel = copyECtoGEM(ecModel, overwrite)
    -0002 % copyECtoGEM
    -0003 %   Copies EC numbers from ecModel.ec.eccodes to ecModel.eccodes.
    -0004 %
    -0005 % Input:
    -0006 %   ecModel     an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0007 %   overwrite   logical that specifies if existing (non-empty)
    -0008 %               ecModel.eccodes entries should be overwritten. Empty
    -0009 %               ecModel.eccodes entries are always overwritten if possible.
    -0010 %               default false.
    -0011 %
    -0012 % Output:
    -0013 %   ecModel     ecModel with populated model.eccodes
    -0014 %
    -0015 % Usage:
    -0016 %   ecModel = getECfromGEM(ecModel, overwrite)
    -0017 
    -0018 if nargin < 2 || isempty(overwrite)
    -0019     overwrite = false;
    -0020 end
    -0021 if ~isfield(ecModel.ec,'eccodes')
    -0022     error('ecModel.ec.eccodes does not exist')
    -0023 end
    -0024 
    -0025 [a,b] = ismember(ecModel.rxns,ecModel.ec.rxns);
    -0026 if ~isfield(ecModel,'eccodes')
    -0027     ecModel.eccodes = cell(numel(ecModel.rxns),1);
    -0028 end
    -0029 
    -0030 if overwrite
    -0031     ecModel.eccodes(a) = ecModel.ec.eccodes(b(a));
    -0032 else % Only replace emptyEcCodes
    -0033     emptyEcCodes = cellfun(@isempty, ecModel.eccodes);
    -0034     a = a & emptyEcCodes;
    -0035     ecModel.eccodes(a) = ecModel.ec.eccodes(b(a));
    -0036 end
    -0037 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/get_enzyme_data/findECInDB.html b/doc/src/geckomat/get_enzyme_data/findECInDB.html deleted file mode 100644 index a90c456f..00000000 --- a/doc/src/geckomat/get_enzyme_data/findECInDB.html +++ /dev/null @@ -1,222 +0,0 @@ - - - - Description of findECInDB - - - - - - - - - -
    Home > src > geckomat > get_enzyme_data > findECInDB.m
    - - - -

    findECInDB -

    - -

    PURPOSE ^

    -
    findECInDB
    - -

    SYNOPSIS ^

    -
    function [EC,conflicts] = findECInDB(gene_set, DBecNum, DBMW, geneIndex, geneHashMap)
    - -

    DESCRIPTION ^

    -
     findECInDB
    -   Collects enzyme codes for genes from the UniProt or KEGGdatabase.
    -
    - Input:
    -   gene_set    genes from a given metabolic reaction
    -   DBecNum     array of EC numbers
    -   DBMW        array of molecular weights in Da
    -   geneIndex   as generated by getECfromDatabase
    -   geneHashMap as generated by getECfromDatabase
    -
    - Output:
    -   EC          all EC numbers found for the genes in gene_set
    -   conflicts   genes with multiple protein matches
    -
    - Usage:
    -   [EC,conflicts] = findECInDB(gene_set, DBecNum, DBMW, geneIndex, geneHashMap)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    • getECstring %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -This function is called by: - - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 function [EC,conflicts] = findECInDB(gene_set, DBecNum, DBMW, geneIndex, geneHashMap)
    -0002 % findECInDB
    -0003 %   Collects enzyme codes for genes from the UniProt or KEGGdatabase.
    -0004 %
    -0005 % Input:
    -0006 %   gene_set    genes from a given metabolic reaction
    -0007 %   DBecNum     array of EC numbers
    -0008 %   DBMW        array of molecular weights in Da
    -0009 %   geneIndex   as generated by getECfromDatabase
    -0010 %   geneHashMap as generated by getECfromDatabase
    -0011 %
    -0012 % Output:
    -0013 %   EC          all EC numbers found for the genes in gene_set
    -0014 %   conflicts   genes with multiple protein matches
    -0015 %
    -0016 % Usage:
    -0017 %   [EC,conflicts] = findECInDB(gene_set, DBecNum, DBMW, geneIndex, geneHashMap)
    -0018 
    -0019 %Preallocate function variables
    -0020 conflicts = cell(1,2);
    -0021 
    -0022 %Split the gene set and match each gene:
    -0023 %gene_set  = strsplit(grRule,' and '); %this string splitting together with getSimpleGeneSets takes 2.6 s, that is ok.
    -0024 EC_set    = cell(size(gene_set));
    -0025 
    -0026 %find index indices of all genes in one call
    -0027 
    -0028 %this loop is slow
    -0029 for j = 1:length(gene_set)
    -0030      gene = gene_set{j};
    -0031      matches = [];
    -0032      %Get the indexes for all of the proteins related to gene
    -0033      if isKey(geneHashMap,gene) %annoyingly, this seems to be needed
    -0034          matchInd = cell2mat(values(geneHashMap,gene_set(j)));
    -0035          matches = geneIndex{matchInd};
    -0036      end
    -0037      if ~isempty(matches)
    -0038         %Get the indexes of the matched protein(s) with non-empty EC#s
    -0039         nonEmpty = matches(~cellfun(@isempty,DBecNum(matches)));
    -0040         if ~isempty(nonEmpty)
    -0041             [geneECs,ia] = unique(DBecNum(nonEmpty),'stable');
    -0042             %For genes with multiple proteins associated to several
    -0043             %non-empty ecNumbers
    -0044             if length(geneECs)>1
    -0045                 indexes = nonEmpty(ia);
    -0046                 ecNum = DBecNum(indexes);
    -0047                 %Save first match
    -0048                 EC_set{j}  = getECstring(EC_set{j},ecNum{1});
    -0049                 %Save additional matches as potential conflicts
    -0050                 if ~ismember(gene,conflicts{1})
    -0051                     conflicts{1} = [conflicts{1}; {gene}];
    -0052                     conflicts{2} = [conflicts{2}; {indexes}]; 
    -0053                 end
    -0054             else
    -0055                 %If there is a single unique ec number for the matched
    -0056                 %protein(s), then choose the lightest protein
    -0057                 [~,minW]   = min(DBMW(nonEmpty));
    -0058                 matches    = nonEmpty(minW);
    -0059                 EC_set{j}  = getECstring(EC_set{j},DBecNum{matches});
    -0060             end
    -0061         end
    -0062     end
    -0063 
    -0064     if isempty(EC_set{j})
    -0065         EC_set{j} = '';
    -0066     end
    -0067 end
    -0068 
    -0069 %EC: Find union and intersection between all units (only applies for
    -0070 %complexes, i.e. length(EC_set) > 1):
    -0071 uni_EC = strsplit(EC_set{1},' ');
    -0072 int_EC = uni_EC;
    -0073 for j = 2:length(EC_set)
    -0074     other_EC = strsplit(EC_set{j},' ');
    -0075     if isempty(uni_EC)
    -0076         uni_EC = other_EC;
    -0077         int_EC = other_EC;
    -0078     elseif ~isempty(other_EC)
    -0079         uni_EC = compare_wild([uni_EC other_EC]);
    -0080         int_EC = intersection(int_EC,other_EC);
    -0081     end
    -0082 end
    -0083 %Use the intersection found, if any. If not, use the union:
    -0084 if isempty(int_EC)
    -0085     EC_set = uni_EC;
    -0086 else
    -0087     EC_set = int_EC;
    -0088 end
    -0089 
    -0090 %Add new codes as new possible isozymes and remove the initial "EC" text:
    -0091 
    -0092 for i = 1:length(EC_set)
    -0093    if ~isempty(EC_set{i}) 
    -0094        EC_set{i} = extractAfter(EC_set{i},2);%remove 2 first chars
    -0095    end
    -0096 end
    -0097 
    -0098 %EC_set = cellfun(@(x) extractAfter(x,2),EC_set,'UniformOutput',false);%remove 2 first chars
    -0099 EC    = strjoin(EC_set,';');
    -0100 
    -0101 
    -0102 %Delete repeated Uniprots (and the corresponding ECs):
    -0103 %EC(deleted)   = []; %Not sure if this needs to be done somehow, don't think so
    -0104 
    -0105 end
    -0106 
    -0107 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0108 function int_EC = intersection(prev_EC,new_EC)
    -0109 %Finds the common elements between two cell arrays, if any. Also considers
    -0110 %wildcards (e.g. if 'EC1.1.1.1' is in one array and 'EC1.1.1.-' is in the
    -0111 %other one, then 'EC1.1.1.1' is added to the intersection).
    -0112 int_EC = {};
    -0113 for i = 1:length(prev_EC)
    -0114     for j = 1:length(new_EC)
    -0115         new_int = compare_wild({prev_EC{i} new_EC{j}});
    -0116         if length(new_int) == 1
    -0117             int_EC = [int_EC new_int];
    -0118         end
    -0119     end
    -0120 end
    -0121 end
    -0122 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0123 function int_EC = compare_wild(EC)
    -0124 %Goes through a cell array of EC numbers, and erases any repetitions,
    -0125 %considering also wildcards (e.g. will erase 'EC1.2.3.-' if 'EC1.2.3.4' is
    -0126 %already present).
    -0127 
    -0128 %Trim all EC numbers of wild cards (e.g. 'EC1.2.-.-' -> 'EC1.2.'):
    -0129 EC_trimmed = EC;
    -0130 for i = 1:length(EC)
    -0131     %Add a final dot for avoiding issues (e.g. 'EC1.1.1.1' & 'EC1.1.1.12'):
    -0132     ECi = [EC{i} '.'];
    -0133     pos = strfind(ECi,'-');
    -0134     if ~isempty(pos)
    -0135         ECi = ECi(1:pos(1)-1);
    -0136     end
    -0137     EC_trimmed{i} = ECi;
    -0138 end
    -0139 
    -0140 %Compare all EC numbers between them to find if 1 fits in the other:
    -0141 non_repeated = true(1,length(EC));
    -0142 for i = 1:length(EC)-1
    -0143     for j = i+1:length(EC)
    -0144         ECi = EC_trimmed{i};
    -0145         ECj = EC_trimmed{j};
    -0146         %If ECj fits in ECi then ECj can be disregarded:
    -0147         if strfind(ECi,ECj)
    -0148             non_repeated(j) = false;
    -0149         %Else, if ECi fits in ECj then ECi can be disregarded:
    -0150         elseif strfind(ECj,ECi)
    -0151             non_repeated(i) = false;
    -0152         end
    -0153     end
    -0154 end
    -0155 
    -0156 int_EC = EC(non_repeated);
    -0157 
    -0158 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/get_enzyme_data/getECfromDatabase.html b/doc/src/geckomat/get_enzyme_data/getECfromDatabase.html deleted file mode 100644 index 1dec3ed3..00000000 --- a/doc/src/geckomat/get_enzyme_data/getECfromDatabase.html +++ /dev/null @@ -1,265 +0,0 @@ - - - - Description of getECfromDatabase - - - - - - - - - -
    Home > src > geckomat > get_enzyme_data > getECfromDatabase.m
    - - - -

    getECfromDatabase -

    - -

    PURPOSE ^

    -
    getECfromDatabase
    - -

    SYNOPSIS ^

    -
    function model = getECfromDatabase(model, ecRxns, action, modelAdapter)
    - -

    DESCRIPTION ^

    -
     getECfromDatabase
    -   Populates the model.ec.eccodes field with enzyme codes that are
    -   extracted from UniProt and KEGG databases, as assigned to the proteins
    -   that catalyze the specific reactions.
    -
    - Input:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   ecRxns          logical of length model.ec.rxns that specifies which
    -                   model.ec.eccodes entries should be queried. Exiting
    -                   values in model.ec.eccodes will be wiped. Entries that
    -                   are indicated by false will be kept and not modified by
    -                   this function (optional, by default all model.ec.eccodes
    -                   entries are populated by this function)
    -   action          response action if multiple proteins with different EC
    -                   numbers are found for a given gene in a metabolic
    -                   reaction (optional, default 'display')
    -                   - 'display' displays all found multiplicities
    -                   - 'ignore'  ignore multiplicities and use the protein
    -                               with the lowest index in the database.
    -                   - 'add'     adds all the multiple proteins as
    -                               isozymes for the given reaction
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -                   default model adapter).
    -
    - Output:
    -   model           ecModel with populated model.ec.eccodes
    -
    - Usage:
    -   model = getECfromDatabase(model, ecRxns, action, modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: - -This function is called by: -
      -
    - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 function model = getECfromDatabase(model, ecRxns, action, modelAdapter)
    -0002 % getECfromDatabase
    -0003 %   Populates the model.ec.eccodes field with enzyme codes that are
    -0004 %   extracted from UniProt and KEGG databases, as assigned to the proteins
    -0005 %   that catalyze the specific reactions.
    -0006 %
    -0007 % Input:
    -0008 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0009 %   ecRxns          logical of length model.ec.rxns that specifies which
    -0010 %                   model.ec.eccodes entries should be queried. Exiting
    -0011 %                   values in model.ec.eccodes will be wiped. Entries that
    -0012 %                   are indicated by false will be kept and not modified by
    -0013 %                   this function (optional, by default all model.ec.eccodes
    -0014 %                   entries are populated by this function)
    -0015 %   action          response action if multiple proteins with different EC
    -0016 %                   numbers are found for a given gene in a metabolic
    -0017 %                   reaction (optional, default 'display')
    -0018 %                   - 'display' displays all found multiplicities
    -0019 %                   - 'ignore'  ignore multiplicities and use the protein
    -0020 %                               with the lowest index in the database.
    -0021 %                   - 'add'     adds all the multiple proteins as
    -0022 %                               isozymes for the given reaction
    -0023 %   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -0024 %                   default model adapter).
    -0025 %
    -0026 % Output:
    -0027 %   model           ecModel with populated model.ec.eccodes
    -0028 %
    -0029 % Usage:
    -0030 %   model = getECfromDatabase(model, ecRxns, action, modelAdapter)
    -0031 
    -0032 if nargin < 2 || isempty(ecRxns)
    -0033     ecRnxs = true(numel(model.ec.rxns),1);
    -0034 end
    -0035 
    -0036 if nargin < 3 || isempty(action)
    -0037     action = 'display';
    -0038 end
    -0039 
    -0040 if nargin < 4 || isempty(modelAdapter)
    -0041     modelAdapter = ModelAdapterManager.getDefault();
    -0042     if isempty(modelAdapter)
    -0043         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0044     end
    -0045 end
    -0046 params = modelAdapter.getParameters();
    -0047 
    -0048 rxnEnzMat = model.ec.rxnEnzMat;
    -0049 genes = modelAdapter.getUniprotCompatibleGenes(model.ec.genes);
    -0050 
    -0051 data    = loadDatabases('both', modelAdapter);
    -0052 uniprot = data.uniprot;
    -0053 kegg    = data.kegg;
    -0054 
    -0055 modelGenes = modelAdapter.getUniprotIDsFromTable(model.genes);
    -0056 DBgenesUniprot  = data.uniprot.genes;
    -0057 if ~isequal(modelGenes,model.genes)
    -0058     [Lia,Locb] = ismember(modelGenes,uniprot.ID);
    -0059     DBgenesUniprot(Locb(Lia)) = model.genes(Lia);
    -0060     keepEntry = unique(Locb(Lia));
    -0061     DBgenesUniprot = DBgenesUniprot(keepEntry);
    -0062 else
    -0063     keepEntry = true(numel(DBgenesUniprot),1);
    -0064 end
    -0065 DBecNumUniprot  = data.uniprot.eccodes(keepEntry);
    -0066 DBMWUniprot     = data.uniprot.MW(keepEntry);
    -0067 %Build an index from gene to prot for faster processing later
    -0068 [geneIndexUniprot,geneHashMapUniprot] = hashGeneToProt(DBgenesUniprot);
    -0069 
    -0070 if ~isempty(kegg)
    -0071     DBgenesKEGG     = data.kegg.genes;
    -0072     DBecNumKEGG     = data.kegg.eccodes;
    -0073     DBMWKEGG        = data.kegg.MW;
    -0074     [geneIndexKEGG,geneHashMapKEGG]       = hashGeneToProt(DBgenesKEGG);
    -0075 end
    -0076 n = size(rxnEnzMat,1);
    -0077 
    -0078 eccodes   = cell(n,1);
    -0079 eccodes(:)= {''};
    -0080 conflicts = cell(1,4);
    -0081 
    -0082 rxnEnzMat = logical(rxnEnzMat);
    -0083 progressbar('Assigning EC numbers from database')
    -0084 for i = 1:n
    -0085     gns = genes(rxnEnzMat(i,:).');
    -0086     if ~isempty(gns)
    -0087         %Find match in Uniprot:
    -0088         [new_EC,multGenes] = findECInDB(gns,DBecNumUniprot,DBMWUniprot,geneIndexUniprot,geneHashMapUniprot);
    -0089         if ~isempty(new_EC)
    -0090             DBase    = 'uniprot';
    -0091             if ~isempty(multGenes{1})
    -0092                 multGenes{3} = DBase;
    -0093             end
    -0094         end
    -0095         if ~isempty(kegg) && (isempty(new_EC) || endsWith(new_EC,'-'))
    -0096             %Find match in KEGG
    -0097             [new_EC_kegg,multGenes] = findECInDB(gns,DBecNumKEGG,DBMWKEGG,geneIndexKEGG,geneHashMapKEGG);
    -0098             if ~isempty(new_EC_kegg)
    -0099                 DBase    = 'kegg';
    -0100                 if ~isempty(multGenes{1})
    -0101                     multGenes{3} = DBase;
    -0102                 end
    -0103                 new_EC=new_EC_kegg;
    -0104             end
    -0105         end
    -0106         eccodes{i} = new_EC;
    -0107 
    -0108         if ~isempty(multGenes{1})
    -0109             %Rxn index
    -0110             conflicts{1} = [conflicts{1};i];
    -0111             %Gene IDs
    -0112             conflicts{2} = [conflicts{2};multGenes{1}];
    -0113             %Indexes in DB
    -0114             conflicts{3} = [conflicts{3};multGenes{2}];
    -0115             %DB name
    -0116             conflicts{4} = [conflicts{4};{multGenes{3}}];
    -0117 
    -0118             %{ I don't understand the purpose of this, let's skip it for now
    -0119             %if strcmpi(action,'add')
    -0120             %    if strcmpi(DBase,'swissprot')
    -0121             %        [uni,EC,MW,Genes] = addMultipleMatches(uni,EC,MW,Genes,multGenes,swissprot);
    -0122             %    elseif strcmpi(DBase,'KEGG')
    -0123             %        [uni,EC,MW,Genes] = addMultipleMatches(uni,EC,MW,Genes,multGenes,kegg);
    -0124             %    end
    -0125             %end
    -0126             %}
    -0127         end
    -0128     end
    -0129     progressbar(i/n)
    -0130 end
    -0131 
    -0132 %Display error message with the multiple gene-protein matches found
    -0133 if strcmpi(action,'display') && ~isempty(conflicts{1})
    -0134     displayErrorMessage(conflicts,uniprot,kegg)
    -0135 end
    -0136 
    -0137 if nargin < 2 || isempty(ecRxns) || all(ecRxns)
    -0138     model.ec.eccodes = eccodes;
    -0139 else
    -0140     if ~isfield(model.ec,'eccodes')
    -0141         model.ec.eccodes(1:numel(model.ec.rxns),1) = {''};
    -0142     end
    -0143     %Probably faster to subset with ecRxns in the beginning of the script,
    -0144     %but this was at the moment simpler to implement.
    -0145     model.ec.eccodes(ecRxns) = eccodes(ecRxns);
    -0146 end
    -0147 
    -0148 function displayErrorMessage(conflicts,uniprot,kegg)
    -0149 STR = ['\n ' num2str(length(conflicts{1})) ' genes with multiple associated proteins were found, please'];
    -0150 STR = [STR, ' revise case by case in the uniprot and kegg files:\n\n'];
    -0151 for i=1:length(conflicts{1})
    -0152     if strcmpi(conflicts{4}{i},'uniprot')
    -0153         DB = uniprot.ID;
    -0154     else
    -0155         DB = kegg.uniprot;
    -0156     end
    -0157     proteins = DB(conflicts{3}{i});
    -0158     STR = [STR, '- gene: ' conflicts{2}{i} '  Proteins: ' strjoin(proteins) '\n'];
    -0159 end
    -0160 STR = [STR, '\nIf a wrongly annotated case was found then call the '];
    -0161 STR = [STR, 'getECfromDatabase.m function again with the option action'];
    -0162 STR = [STR, '= ignore\n\n'];
    -0163 STR = [STR, 'If the conflicting proteins are desired to be kept as isozymes'];
    -0164 STR = [STR, ' then call the getECfromDatabase.m function'];
    -0165 STR = [STR, ' again with the option action = add\n'];
    -0166 error(sprintf(STR))
    -0167 end
    -0168 
    -0169 function [geneIndex,geneHashMap]=hashGeneToProt(proteinDB)
    -0170 
    -0171 [x,y] = size(proteinDB);
    -0172 genesForIndex = reshape(proteinDB, x*y, 1);
    -0173 genesForIndex = genesForIndex(~cellfun(@isempty, genesForIndex));
    -0174 genesForIndex = unique(genesForIndex);
    -0175 geneIndex = cell(length(genesForIndex),1);
    -0176 geneHashMap = containers.Map(genesForIndex,1:length(genesForIndex));
    -0177 protIndices = 1:length(proteinDB(:,1));
    -0178 for i = 1:y
    -0179     tmp1 = proteinDB(:,i);
    -0180     sel = ~cellfun(@isempty, tmp1);
    -0181     indices = cell2mat(values(geneHashMap,tmp1(sel)));
    -0182     protIndicesSel = protIndices(sel);
    -0183     for j = 1:length(indices)
    -0184         geneIndex{indices(j)} = [geneIndex{indices(j)};protIndicesSel(j)];
    -0185     end
    -0186 end
    -0187 end
    -0188 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/get_enzyme_data/getECfromGEM.html b/doc/src/geckomat/get_enzyme_data/getECfromGEM.html deleted file mode 100644 index a56cb9d2..00000000 --- a/doc/src/geckomat/get_enzyme_data/getECfromGEM.html +++ /dev/null @@ -1,130 +0,0 @@ - - - - Description of getECfromGEM - - - - - - - - - -
    Home > src > geckomat > get_enzyme_data > getECfromGEM.m
    - - - -

    getECfromGEM -

    - -

    PURPOSE ^

    -
    getECfromGEM
    - -

    SYNOPSIS ^

    -
    function [model, invalidEC, invalidECpos] = getECfromGEM(model, ecRxns)
    - -

    DESCRIPTION ^

    -
     getECfromGEM
    -   Use the model.eccodes to populates the model.ec.eccodes field. EC
    -   numbers that are not formatted as four numbers separated by periods,
    -   possibly with trailing wildcards. Examples: 1.2.3.4 or 1.2.3.- while
    -   invalid EC numbers are 1.2.3 or 1_2_3_4. Multiple EC numbers are
    -   separated by ; for instance 1.2.3.4;1.2.3.5 not 1.2.3.4|1.2.3.5.
    -
    - Input:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   ecRxns          logical of length model.ec.rxns that specifies for
    -                   which reactions the existing model.ec.eccodes entry
    -                   should be kept and not modified by this function
    -                   (optional, by default all model.ec.eccodes entries
    -                   are populated by this function)
    -
    - Output:
    -   model           ecModel with populated model.ec.eccodes
    -   invalidEC       incorrectly formatted EC numbers
    -   invalidECpos    position of invalidEC in model.eccodes
    -
    - Usage:
    -   [model, invalidEC, invalidECpos] = getECfromGEM(model, ecRxns)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function [model, invalidEC, invalidECpos] = getECfromGEM(model, ecRxns)
    -0002 % getECfromGEM
    -0003 %   Use the model.eccodes to populates the model.ec.eccodes field. EC
    -0004 %   numbers that are not formatted as four numbers separated by periods,
    -0005 %   possibly with trailing wildcards. Examples: 1.2.3.4 or 1.2.3.- while
    -0006 %   invalid EC numbers are 1.2.3 or 1_2_3_4. Multiple EC numbers are
    -0007 %   separated by ; for instance 1.2.3.4;1.2.3.5 not 1.2.3.4|1.2.3.5.
    -0008 %
    -0009 % Input:
    -0010 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0011 %   ecRxns          logical of length model.ec.rxns that specifies for
    -0012 %                   which reactions the existing model.ec.eccodes entry
    -0013 %                   should be kept and not modified by this function
    -0014 %                   (optional, by default all model.ec.eccodes entries
    -0015 %                   are populated by this function)
    -0016 %
    -0017 % Output:
    -0018 %   model           ecModel with populated model.ec.eccodes
    -0019 %   invalidEC       incorrectly formatted EC numbers
    -0020 %   invalidECpos    position of invalidEC in model.eccodes
    -0021 %
    -0022 % Usage:
    -0023 %   [model, invalidEC, invalidECpos] = getECfromGEM(model, ecRxns)
    -0024 
    -0025 if ~isfield(model,'eccodes')
    -0026     error('The model has no model.eccodes field.')
    -0027 end
    -0028 
    -0029 %Need to remove the prefix of GECKO light rxn names in the ec structure
    -0030 if ~model.ec.geckoLight
    -0031     rxnNames = model.ec.rxns;
    -0032 else
    -0033     rxnNames = extractAfter(model.ec.rxns, 4);
    -0034 end
    -0035 
    -0036 [~,rxnIdxs] = ismember(rxnNames,model.rxns);
    -0037 
    -0038 % Check if eccodes are valid
    -0039 eccodes = model.eccodes;
    -0040 invalidEC = regexprep(eccodes,'(\d\.(\w|-)+\.(\w|-)+\.(\w|-)+)(;\w+\.(\w|-)+\.(\w|-)+\.(\w|-)+)*(.*)','$3');
    -0041 invalidEC = ~cellfun(@isempty,invalidEC);
    -0042 invalidECpos = find(invalidEC);
    -0043 if any(invalidECpos)
    -0044     invalidEC = model.eccodes(invalidEC);
    -0045     if nargout<2
    -0046         fprintf('Skipped incorrectly formatted EC numbers, rerun getECfromGEM with all outputs to get a list.\n')
    -0047     else
    -0048         fprintf('Skipped incorrectly formatted EC numbers.\n')
    -0049     end
    -0050     eccodes(invalidECpos)={''};
    -0051 else
    -0052     invalidEC = [];
    -0053 end
    -0054 if nargin<2 || all(ecRxns)
    -0055     model.ec.eccodes = eccodes(rxnIdxs);
    -0056 else
    -0057     if ~isfield(model.ec,'eccodes')
    -0058         model.ec.eccodes(1:numel(model.ec.rxns),1) = {''};
    -0059     end
    -0060     model.ec.eccodes(ecRxns) = eccodes(rxnIdxs(ecRxns));
    -0061 end
    -0062 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/get_enzyme_data/getECstring.html b/doc/src/geckomat/get_enzyme_data/getECstring.html deleted file mode 100644 index e9e930a8..00000000 --- a/doc/src/geckomat/get_enzyme_data/getECstring.html +++ /dev/null @@ -1,73 +0,0 @@ - - - - Description of getECstring - - - - - - - - - -
    Home > src > geckomat > get_enzyme_data > getECstring.m
    - - - -

    getECstring -

    - -

    PURPOSE ^

    -
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    - -

    SYNOPSIS ^

    -
    function EC_set = getECstring(EC_set,ecNumbers)
    - -

    DESCRIPTION ^

    -
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    - EC_set = getECstring(EC_set,ecNumbers)
    - 
    - Provides a single string with all the EC numbers associated to a given
    - protein with according to the next format: "ECX.X.X.X ECX.X.X.X ECX.X.X.X"
    -
    - Ivan Domenzain.      Last edited: 2018-09-06
    -%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -In case of several ec numbers for the same protein
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: - - - - - -

    SOURCE CODE ^

    -
    0001 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0002 % EC_set = getECstring(EC_set,ecNumbers)
    -0003 %
    -0004 % Provides a single string with all the EC numbers associated to a given
    -0005 % protein with according to the next format: "ECX.X.X.X ECX.X.X.X ECX.X.X.X"
    -0006 %
    -0007 % Ivan Domenzain.      Last edited: 2018-09-06
    -0008 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0009 function EC_set = getECstring(EC_set,ecNumbers)
    -0010 %In case of several ec numbers for the same protein
    -0011 new_EC_set = replace(strsplit(ecNumbers,' '),';','');
    -0012 for l = 1:length(new_EC_set)
    -0013     EC_set = [EC_set 'EC' new_EC_set{l}];
    -0014     if l<length(new_EC_set)
    -0015         EC_set = [EC_set ' '];
    -0016     end
    -0017 end
    -0018 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/get_enzyme_data/index.html b/doc/src/geckomat/get_enzyme_data/index.html deleted file mode 100644 index 83fceec5..00000000 --- a/doc/src/geckomat/get_enzyme_data/index.html +++ /dev/null @@ -1,29 +0,0 @@ - - - - Index for Directory src\geckomat\get_enzyme_data - - - - - - - - - - -
    < Master indexIndex for src\geckomat\get_enzyme_data >
    - -

    Index for src\geckomat\get_enzyme_data

    - -

    Matlab files in this directory:

    - -
     calculateMW%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
     copyECtoGEMcopyECtoGEM
     findECInDBfindECInDB
     getECfromDatabasegetECfromDatabase
     getECfromGEMgetECfromGEM
     getECstring%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
     loadBRENDAdata%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
     loadDatabasesloadDatabases
    - - - - -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/get_enzyme_data/loadBRENDAdata.html b/doc/src/geckomat/get_enzyme_data/loadBRENDAdata.html deleted file mode 100644 index 69ad5586..00000000 --- a/doc/src/geckomat/get_enzyme_data/loadBRENDAdata.html +++ /dev/null @@ -1,130 +0,0 @@ - - - - Description of loadBRENDAdata - - - - - - - - - -
    Home > src > geckomat > get_enzyme_data > loadBRENDAdata.m
    - - - -

    loadBRENDAdata -

    - -

    PURPOSE ^

    -
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    - -

    SYNOPSIS ^

    -
    function [KCATcell, SAcell] = loadBRENDAdata(modelAdapter)
    - -

    DESCRIPTION ^

    -
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0002 function [KCATcell, SAcell] = loadBRENDAdata(modelAdapter)
    -0003 
    -0004 if nargin < 1 || isempty(modelAdapter)
    -0005     modelAdapter = ModelAdapterManager.getDefault();
    -0006     if isempty(modelAdapter)
    -0007         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0008     end
    -0009 end
    -0010 
    -0011 basePath      = modelAdapter.getBrendaDBFolder();
    -0012 KCAT_file      = fullfile(basePath,'max_KCAT.txt');
    -0013 SA_file        = fullfile(basePath,'max_SA.txt');
    -0014 MW_file        = fullfile(basePath,'max_MW.txt');
    -0015 
    -0016 %Extract BRENDA DATA from files information
    -0017 KCATcell       = openDataFile(KCAT_file,1);
    -0018 scalingFactor = 1/60;    %[umol/min/mg] -> [mmol/s/g]    Old: 60 [umol/min/mg] -> [mmol/h/g]
    -0019 SA            = openDataFile(SA_file,scalingFactor);
    -0020 scalingFactor = 1/1000;  %[g/mol] -> [g/mmol]
    -0021 MW            = openDataFile(MW_file,scalingFactor);
    -0022 
    -0023 for i=1:4
    -0024     SAcell{i} = [];
    -0025 end
    -0026 previousEC = []; EC_indexes = [];
    -0027 
    -0028 %build an index on MW{1} to speed things up a bit
    -0029 %first just extract the genus (i.e. the first part of the name)
    -0030 MWECNum = upper(unique(MW{1}));
    -0031 MWECNumIndices = cell(length(MWECNum),1);
    -0032 MWECNumHashMap = containers.Map(MWECNum,1:length(MWECNum));
    -0033 for i = 1:length(MW{1})
    -0034     matchInd = cell2mat(values(MWECNumHashMap, MW{1}(i)));
    -0035     MWECNumIndices{matchInd} = [MWECNumIndices{matchInd};i];
    -0036 end
    -0037 
    -0038 
    -0039 for i=1:length(SA{1})
    -0040     %Gets the indexes of the EC repetitions in the MW cell for every
    -0041     %new (different) EC
    -0042     if ~strcmpi(SA{1}(i), previousEC)
    -0043         key = upper(SA{1}(i));
    -0044         if isKey(MWECNumHashMap,key) %annoyingly, this seems to be needed
    -0045             matchInd = cell2mat(values(MWECNumHashMap,key));
    -0046             EC_indexes = MWECNumIndices{matchInd};
    -0047         else
    -0048             EC_indexes = [];
    -0049         end
    -0050     end
    -0051     mwEC{1} = MW{3}(EC_indexes); mwEC{2} = MW{4}(EC_indexes);
    -0052     % just looks for the first match because just the maximal value for
    -0053     % each EC# / Orgaism is reported on the file
    -0054     org_index = find(strcmpi(SA{3}(i),mwEC{1}),1);
    -0055     if ~isempty(org_index)
    -0056         SAcell{1} = [SAcell{1};SA{1}(i)];
    -0057         SAcell{2} = [SAcell{2};SA{3}(i)];
    -0058         SAcell{3} = [SAcell{3}; SA{4}(i)*mwEC{2}(org_index)]; %[1/hr]
    -0059         SAcell{4} = [SAcell{4}; mwEC{2}(org_index)];
    -0060     end
    -0061     previousEC = SA{1}(i);
    -0062 end
    -0063 
    -0064 %remove EC in front of all the EC numbers
    -0065 if ~isempty(KCATcell{1})
    -0066     KCATcell{1} = extractAfter(KCATcell{1},2);
    -0067 end
    -0068 if ~isempty(SAcell{1})
    -0069     SAcell{1} = extractAfter(SAcell{1},2);
    -0070 end
    -0071 
    -0072 function data_cell = openDataFile(fileName,scalingFactor)
    -0073 fID          = fopen(fileName);
    -0074 data_cell    = textscan(fID,'%q %q %q %f %q','delimiter','\t');
    -0075 fclose(fID);
    -0076 data_cell{4} = data_cell{4}*scalingFactor;
    -0077 %Split string for each organism in the BRENDA data
    -0078 %{name, taxonomy, KEGG code}
    -0079 data_cell{3}  = regexprep(data_cell{3},'\/\/.*','');
    -0080 end
    -0081 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/get_enzyme_data/loadDatabases.html b/doc/src/geckomat/get_enzyme_data/loadDatabases.html deleted file mode 100644 index 8081de2b..00000000 --- a/doc/src/geckomat/get_enzyme_data/loadDatabases.html +++ /dev/null @@ -1,283 +0,0 @@ - - - - Description of loadDatabases - - - - - - - - - -
    Home > src > geckomat > get_enzyme_data > loadDatabases.m
    - - - -

    loadDatabases -

    - -

    PURPOSE ^

    -
    loadDatabases
    - -

    SYNOPSIS ^

    -
    function databases = loadDatabases(selectDatabase,modelAdapter)
    - -

    DESCRIPTION ^

    -
     loadDatabases
    -   Loads (and downloads if necessary) the organism-specific KEGG and
    -   UniProt databases that are required to extract protein information. The
    -   uniprot.ID and kegg.ID are taken from the ModelAdapter.
    -
    - Input:
    -   selectDatabase  which databases should be loaded, either 'uniprot',
    -                   'kegg' or 'both' (optional, default 'both')
    -   modelAdapter    Model adapter. Optional, default will use the default 
    -                   model adapter (send in [] for default).
    -
    - Output:
    -   databases       contains .uniprot and .kegg structures, dependent on
    -                   which databases were selected.
    -
    - Usage:
    -   databases = loadDatabases(selectDatabase,modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    • calculateMW %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -This function is called by: - - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 function databases = loadDatabases(selectDatabase,modelAdapter)
    -0002 % loadDatabases
    -0003 %   Loads (and downloads if necessary) the organism-specific KEGG and
    -0004 %   UniProt databases that are required to extract protein information. The
    -0005 %   uniprot.ID and kegg.ID are taken from the ModelAdapter.
    -0006 %
    -0007 % Input:
    -0008 %   selectDatabase  which databases should be loaded, either 'uniprot',
    -0009 %                   'kegg' or 'both' (optional, default 'both')
    -0010 %   modelAdapter    Model adapter. Optional, default will use the default
    -0011 %                   model adapter (send in [] for default).
    -0012 %
    -0013 % Output:
    -0014 %   databases       contains .uniprot and .kegg structures, dependent on
    -0015 %                   which databases were selected.
    -0016 %
    -0017 % Usage:
    -0018 %   databases = loadDatabases(selectDatabase,modelAdapter)
    -0019 
    -0020 if nargin<1
    -0021     selectDatabase = 'both';
    -0022 end
    -0023 
    -0024 if nargin < 2 || isempty(modelAdapter)
    -0025     modelAdapter = ModelAdapterManager.getDefault();
    -0026     if isempty(modelAdapter)
    -0027         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0028     end
    -0029 end
    -0030 
    -0031 params      = modelAdapter.getParameters();
    -0032 kegg.ID      = params.kegg.ID;
    -0033 uniprot.ID   = params.uniprot.ID;
    -0034 filePath    = fullfile(params.path,'data');
    -0035 uniprot.geneIDfield = params.uniprot.geneIDfield;
    -0036 uniprot.type = params.uniprot.type;
    -0037 if strcmp(uniprot.type,'taxonomy')
    -0038     uniprot.type = 'taxonomy_id';
    -0039 end
    -0040 kegg.geneID = params.kegg.geneID;
    -0041 if params.uniprot.reviewed
    -0042     uniprotRev = 'reviewed:true+AND+';
    -0043 else
    -0044     uniprotRev = '';
    -0045 end
    -0046 
    -0047 warning('off', 'MATLAB:MKDIR:DirectoryExists');
    -0048 
    -0049 databases.uniprot = [];
    -0050 databases.kegg = [];
    -0051 
    -0052 %% Uniprot
    -0053 if any(strcmp(selectDatabase,{'uniprot','both'}))
    -0054     uniprotPath = fullfile(filePath,'uniprot.tsv');
    -0055     if ~exist(uniprotPath,'file')
    -0056         if isempty(uniprot.ID)
    -0057             printOrange('WARNING: No uniprot.ID is specified, unable to download UniProt DB.\n');
    -0058         end
    -0059         disp(['Downloading Uniprot data for ' uniprot.type ' ' uniprot.ID '. This can take a few minutes.'])
    -0060         url = ['https://rest.uniprot.org/uniprotkb/stream?query=' uniprotRev ...
    -0061                uniprot.type ':' num2str(uniprot.ID) '&fields=accession%2C' uniprot.geneIDfield ...
    -0062             '%2Cec%2Cmass%2Csequence&format=tsv&compressed=false&sort=protein_name%20asc'];
    -0063         try
    -0064             urlwrite(url,uniprotPath,'Timeout',30);
    -0065             fprintf('Model-specific UniProt database stored at %s\n',uniprotPath);
    -0066         catch
    -0067             error(['Download failed, check your internet connection and try again, or manually download: ' url ...
    -0068                 ' After downloading, store the file as ' uniprotPath])
    -0069         end
    -0070     end
    -0071     if exist(uniprotPath,'file')
    -0072         fid         = fopen(uniprotPath,'r');
    -0073         fileContent = textscan(fid,'%q %q %q %q %q','Delimiter','\t','HeaderLines',1);
    -0074         fclose(fid);
    -0075         databases.uniprot.ID      = fileContent{1};
    -0076         databases.uniprot.genes   = fileContent{2};
    -0077         databases.uniprot.eccodes = fileContent{3};
    -0078         databases.uniprot.MW      = str2double(fileContent{4});
    -0079         databases.uniprot.seq     = fileContent{5};
    -0080     else
    -0081         databases.uniprot = [];
    -0082     end
    -0083     if ~isempty(databases.uniprot)
    -0084         [uniqueIDs,uniqueIdx] = unique(databases.uniprot.ID,'stable');
    -0085         if numel(uniqueIDs) < numel(databases.uniprot.ID)
    -0086             duplID = setdiff(1:numel(databases.uniprot.ID),uniqueIdx);
    -0087             dispEM(['Duplicate entries are found for the following proteins. '...
    -0088                     'Manually curate the ''uniprot.tsv'' file, or adjust the uniprot parameters '...
    -0089                     'in the model adapter:'],true,databases.uniprot.ID(duplID));
    -0090         end
    -0091     end
    -0092 end
    -0093 
    -0094 %% KEGG
    -0095 if any(strcmp(selectDatabase,{'kegg','both'}))
    -0096     keggPath = fullfile(filePath,'kegg.tsv');
    -0097     if ~exist(keggPath,'file')
    -0098         if isempty(kegg.ID)
    -0099             printOrange('WARNING: No kegg.ID is specified, unable to download KEGG DB.\n');
    -0100         else
    -0101             downloadKEGG(kegg.ID,keggPath,kegg.geneID);
    -0102         end
    -0103     end
    -0104     if exist(keggPath,'file')
    -0105         fid         = fopen(keggPath,'r');
    -0106         fileContent = textscan(fid,'%q %q %q %q %q %q %q','Delimiter',',','HeaderLines',0);
    -0107         fclose(fid);
    -0108         databases.kegg.uniprot    = fileContent{1};
    -0109         databases.kegg.genes      = fileContent{2};
    -0110         databases.kegg.keggGene   = fileContent{3};
    -0111         databases.kegg.eccodes    = fileContent{4};
    -0112         databases.kegg.MW         = str2double(fileContent{5});
    -0113         databases.kegg.pathway    = fileContent{6};
    -0114         databases.kegg.seq        = fileContent{7};
    -0115     else
    -0116         databases.kegg = [];
    -0117     end
    -0118 end
    -0119 end
    -0120 
    -0121 function downloadKEGG(keggID, filePath, keggGeneID)
    -0122 %% Download gene information
    -0123 progressbar(['Downloading KEGG data for organism code ' keggID])
    -0124 webOptions = weboptions('Timeout',30);
    -0125 try
    -0126     gene_list = webread(['http://rest.kegg.jp/list/' keggID],webOptions);
    -0127 catch ME
    -0128     switch ME.identifier
    -0129         case 'MATLAB:webservices:HTTP400StatusCodeError'
    -0130             error(['Unable to download data form KEGG with a potentially invalid ID: ' keggID ])
    -0131     end
    -0132 end
    -0133 gene_list = regexpi(gene_list, '[^\n]+','match')';
    -0134 gene_id   = regexpi(gene_list,['(?<=' keggID ':)\S+'],'match');
    -0135 
    -0136 % Retrieve information for every gene in the list, 10 genes per query
    -0137 genesPerQuery = 10;
    -0138 queries = ceil(numel(gene_id)/genesPerQuery);
    -0139 keggData  = cell(numel(gene_id),1);
    -0140 for i = 1:queries
    -0141     % Download batches of genes
    -0142     firstIdx = i*genesPerQuery-(genesPerQuery-1);
    -0143     lastIdx  = i*genesPerQuery;
    -0144     if lastIdx > numel(gene_id) % Last query has probably less genes
    -0145         lastIdx = numel(gene_id);
    -0146     end
    -0147     url      = ['http://rest.kegg.jp/get/' keggID ':' strjoin([gene_id{firstIdx:lastIdx}],['+' keggID ':'])];
    -0148 
    -0149     retry = true;
    -0150     while retry
    -0151         try
    -0152             retry = false;
    -0153             out   = webread(url,webOptions);
    -0154         catch
    -0155             retry = true;
    -0156         end
    -0157     end
    -0158     outSplit = strsplit(out,['///' 10]); %10 is new line character
    -0159     if numel(outSplit) < lastIdx-firstIdx+2
    -0160         error('KEGG returns less genes per query') %Reduce genesPerQuery
    -0161     end
    -0162     keggData(firstIdx:lastIdx) = outSplit(1:end-1);
    -0163     progressbar(i/queries)
    -0164 end
    -0165 
    -0166 %% Parsing of info to keggDB format
    -0167 sequence  = regexprep(keggData,'.*AASEQ\s+\d+\s+([A-Z\s])+?\s+NTSEQ.*','$1');
    -0168 %No AASEQ -> no protein -> not of interest
    -0169 noProt    = startsWith(sequence,'ENTRY ');
    -0170 uni       = regexprep(keggData,'.*UniProt: (\S+?)\s.*','$1');
    -0171 noUni     = startsWith(uni,'ENTRY ');
    -0172 uni(noProt | noUni)       = [];
    -0173 keggData(noProt | noUni) = [];
    -0174 sequence(noProt | noUni)  = [];
    -0175 sequence  = regexprep(sequence,'\s*','');
    -0176 keggGene  = regexprep(keggData,'ENTRY\s+(\S+?)\s.+','$1');
    -0177 
    -0178 switch keggGeneID
    -0179     case {'kegg',''}
    -0180         gene_name = keggGene;
    -0181     otherwise
    -0182         % In case there are special characters:
    -0183         keggGeneIDT = regexptranslate('escape',keggGeneID);
    -0184         gene_name = regexprep(keggData,['.+' keggGeneIDT ': (\S+?)\n.+'],'$1');
    -0185         noID = ~contains(keggData,keggGeneIDT);
    -0186         if all(noID)
    -0187             error(['None of the KEGG entries are annotated with the gene identifier ' keggGeneID])
    -0188         else
    -0189             gene_name(noID)= [];
    -0190             keggData(noID) = [];
    -0191             keggGene(noID) = [];
    -0192             sequence(noID) = [];
    -0193             uni(noID)      = [];
    -0194         end
    -0195 end
    -0196 
    -0197 EC_names  = regexprep(keggData,'.*ORTHOLOGY.*\[EC:(.*?)\].*','$1');
    -0198 EC_names(startsWith(EC_names,'ENTRY ')) = {''};
    -0199 
    -0200 MW = cell(numel(sequence),1);
    -0201 for i=1:numel(sequence)
    -0202     if ~isempty(sequence{i})
    -0203         MW{i} = num2str(round(calculateMW(sequence{i})));
    -0204     end
    -0205 end
    -0206 
    -0207 pathway   = regexprep(keggData,'.*PATHWAY\s+(.*?)(BRITE|MODULE).*','$1');
    -0208 pathway(startsWith(pathway,'ENTRY ')) = {''};
    -0209 pathway   = strrep(pathway,[keggID '01100  Metabolic pathways'],'');
    -0210 pathway   = regexprep(pathway,'\n','');
    -0211 pathway   = regexprep(pathway,'           ','');
    -0212 
    -0213 out = [uni, gene_name, keggGene, EC_names, MW, pathway, sequence];
    -0214 out = cell2table(out);
    -0215 
    -0216 writetable(out, filePath, 'FileType', 'text', 'WriteVariableNames',false);
    -0217 fprintf('Model-specific KEGG database stored at %s\n',filePath);
    -0218 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/abc_max.html b/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/abc_max.html deleted file mode 100644 index f85f1fa6..00000000 --- a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/abc_max.html +++ /dev/null @@ -1,176 +0,0 @@ - - - - Description of abc_max - - - - - - - - - - - - - -

    abc_max -

    - -

    PURPOSE ^

    -
    abc_max
    - -

    SYNOPSIS ^

    -
    function [rmse,rmseList] = abc_max(ecModel,fluxData,maxGrowth,rxn2block,modelAdapter)
    - -

    DESCRIPTION ^

    -
     abc_max
    -   Internal function in BayesianSensitivityTuning. Gets the average RMSE for
    -   a certain set of growth data and kcats.
    -
    - Input:
    -   ecModel       ecModel that was generated by makeEcModel, or loaded from
    -                 an earlier run. Not compatible with ecModels generated by
    -                 earlier GECKO versions (pre 3.0).
    -   fluxData      Growth data loaded from file.
    -   maxGrowth     Max growth data loaded from file.
    -   rxn2block     List of reactions to block, could be read from file.
    -
    - Output:
    -   rmse          The average RMSE
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: - -This function is called by: - - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 function [rmse,rmseList] = abc_max(ecModel,fluxData,maxGrowth,rxn2block,modelAdapter)
    -0002 % abc_max
    -0003 %   Internal function in BayesianSensitivityTuning. Gets the average RMSE for
    -0004 %   a certain set of growth data and kcats.
    -0005 %
    -0006 % Input:
    -0007 %   ecModel       ecModel that was generated by makeEcModel, or loaded from
    -0008 %                 an earlier run. Not compatible with ecModels generated by
    -0009 %                 earlier GECKO versions (pre 3.0).
    -0010 %   fluxData      Growth data loaded from file.
    -0011 %   maxGrowth     Max growth data loaded from file.
    -0012 %   rxn2block     List of reactions to block, could be read from file.
    -0013 %
    -0014 % Output:
    -0015 %   rmse          The average RMSE
    -0016 
    -0017 if nargin < 5 || isempty(modelAdapter)
    -0018     modelAdapter = ModelAdapterManager.getDefault();
    -0019     if isempty(modelAdapter)
    -0020         error('Either send in a modelAdapter or set the default ecModel adapter in the ModelAdapterManager.')
    -0021     end
    -0022 end
    -0023 rmse_1 = []; rmseList1 = []; rmse_2 = []; rmseList2 = [];
    -0024 
    -0025 if ~isfield(ecModel,'excarbon')
    -0026     ecModel = addCarbonNum(ecModel);
    -0027     ecModel.excarbon(ecModel.excarbon == 0) = 1;
    -0028 end
    -0029 
    -0030 %% First test with flux data
    -0031 if ~isempty(fluxData)
    -0032     [rmse_1, rmseList1] = rmsecal(ecModel,fluxData,true,rxn2block,modelAdapter);
    -0033     rmseList1 = [cellstr("fluxData_" + string(1:numel(rmseList1)))',num2cell(rmseList1)];
    -0034 end
    -0035 %% Second test with maximum growth on various carbon sources
    -0036 if ~isempty(maxGrowth)  % simulate the maximal growth rate
    -0037     [rmse_2, rmseList2] = rmsecal(ecModel,maxGrowth,false,rxn2block,modelAdapter);
    -0038     rmseList2 = [cellstr("maxGrowth_" + string(1:numel(rmseList2)))',num2cell(rmseList2)];
    -0039 end
    -0040     
    -0041 %% Combine results
    -0042 rmse        = mean([rmse_1,rmse_2],'omitnan');
    -0043 rmseList    = [rmseList1;rmseList2];
    -0044 end
    -0045 
    -0046 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0047 function [rmse, rmseList] = rmsecal(ecModel,data,constrain,rxn2block,modelAdapter)
    -0048 
    -0049 rmseList = zeros(length(data.conds),1);
    -0050 
    -0051 for i = 1:length(data.conds)
    -0052 
    -0053     % Set carbon source
    -0054     [~,exchIdx] = ismember(data.conds,data.exchMets);
    -0055     if any(exchIdx == 0)
    -0056         missingMets = strjoin(unique(data.conds(exchIdx == 0 )), '; ');
    -0057         error('Carbon source(s) "%s" in the provided fluxData or maxGrowth cannot be matched by name with an exchange reaction.', missingMets);
    -0058     end
    -0059     % Set all other carbon sources to zero
    -0060     model_tmp = setParam(ecModel,'lb',data.exchRxnIDs(unique(exchIdx)),0);
    -0061     % Only allow condition-specific carbon source
    -0062     if constrain % If RMSE is calculated from flux data, then constrain carbon uptake
    -0063         model_tmp = setParam(model_tmp,'lb',data.exchRxnIDs(exchIdx(i)),data.exchFluxes(i,exchIdx(i)));
    -0064     else % If RMSE is calculated from max growth, then do not constrain carbon uptake
    -0065         model_tmp = setParam(model_tmp,'lb',data.exchRxnIDs(exchIdx(i)),-1000);
    -0066     end
    -0067     
    -0068     % Remove carbon source exchange from rxn2block
    -0069     rxn2blockIter = rxn2block;
    -0070     rxn2blockIter(strcmp(rxn2blockIter,data.exchRxnIDs(exchIdx(i)))) = [];
    -0071 
    -0072     % Make anaerobic if relevant
    -0073     o2Flux = data.exchFluxes(i,strcmp('oxygen',data.exchMets));
    -0074     if o2Flux == 0
    -0075         model_tmp = modelAdapter.makeModelAnaerobic(model_tmp);
    -0076     end
    -0077 
    -0078     sol = solveLP(model_tmp);
    -0079     if checkSolution(sol)
    -0080         bioRxn          = getIndexes(model_tmp,data.biomass,'rxns');
    -0081         % Assume that biomass contains 41 Cmmol/gDCW
    -0082         bioMeas         = data.grRate(i) * 41;
    -0083         bioSim          = sol.x(bioRxn) * 41;
    -0084 
    -0085         if constrain
    -0086             fluxToCheck     = ~isnan(data.exchFluxes(i,:));
    -0087             fluxRxnIdx      = getIndexes(model_tmp,data.exchRxnIDs(fluxToCheck),'rxns');
    -0088             cNormMeasFlux   = model_tmp.excarbon(fluxRxnIdx) .* transpose(data.exchFluxes(i,fluxToCheck));
    -0089             cNormSimFlux    = model_tmp.excarbon(fluxRxnIdx) .* sol.x(fluxRxnIdx);
    -0090 
    -0091             % Make sure that selected exchange reactions have zero flux
    -0092             blockRxnIdx     = getIndexes(model_tmp,rxn2blockIter,'rxns');
    -0093             blockSim        = sol.x(blockRxnIdx) .* model_tmp.excarbon(blockRxnIdx);
    -0094             zeroFlux        = blockSim == 0;
    -0095             blockSim(zeroFlux) = [];
    -0096             blockMeas       = zeros(numel(blockSim),1);
    -0097 
    -0098             measured    = [cNormMeasFlux; bioMeas; blockMeas];
    -0099             simulated   = [cNormSimFlux; bioSim; blockSim];
    -0100         else
    -0101             measured    = bioMeas;
    -0102             simulated   = bioSim;
    -0103         end
    -0104         rmseList(i) = sqrt(mse(measured,simulated));
    -0105     else
    -0106         rmseList(i) = NaN;
    -0107     end
    -0108 end
    -0109 rmseList(isnan(rmseList)) = 99; % High penalty for models that failed
    -0110 if isfield(data,'bayesianRMSEweight')
    -0111     rmseList = rmseList .* data.bayesianRMSEweight;
    -0112 end
    -0113 rmse = mean(rmseList);
    -0114 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/addCarbonNum.html b/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/addCarbonNum.html deleted file mode 100644 index 1783c4a7..00000000 --- a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/addCarbonNum.html +++ /dev/null @@ -1,361 +0,0 @@ - - - - Description of addCarbonNum - - - - - - - - - - - - - -

    addCarbonNum -

    - -

    PURPOSE ^

    -
    addCarbonNum
    - -

    SYNOPSIS ^

    -
    function model = addCarbonNum(model)
    - -

    DESCRIPTION ^

    -
     addCarbonNum
    -   Adds a carbon number field to the model.
    -
    - Input:
    -   model           ecModel that was generated by makeEcModel, or loaded from
    -                   an earlier run. Not compatible with ecModels generated by
    -                   earlier GECKO versions (pre 3.0).
    - Output:
    -   model           ecModel
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: - - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 function model = addCarbonNum(model)
    -0002 % addCarbonNum
    -0003 %   Adds a carbon number field to the model.
    -0004 %
    -0005 % Input:
    -0006 %   model           ecModel that was generated by makeEcModel, or loaded from
    -0007 %                   an earlier run. Not compatible with ecModels generated by
    -0008 %                   earlier GECKO versions (pre 3.0).
    -0009 % Output:
    -0010 %   model           ecModel
    -0011 %
    -0012 
    -0013 % get carbonnum for each exchange rxn to further calculation of error
    -0014 model.excarbon = zeros(length(model.rxns),1);
    -0015 [EXrxn, EXrxnIdx] = getExchangeRxns(model);
    -0016 [CarbonNum,EXfors] = getcarbonnum(model,EXrxn);
    -0017 model.excarbon(EXrxnIdx) = CarbonNum;
    -0018 model.excarbon(strcmp(model.rxnNames,'growth')) = 41;
    -0019 
    -0020 function [CarbonNum,EXfors,changedmets] = getcarbonnum(model,exrxn)
    -0021 % getcarbonnum
    -0022 %   Gets carbon numbers matching the model.
    -0023 %
    -0024 % Input:
    -0025 %   model           ecModel that was generated by makeEcModel, or loaded from
    -0026 %                   an earlier run. Not compatible with ecModels generated by
    -0027 %                   earlier GECKO versions (pre 3.0).
    -0028 %   exrxn           Exchange reaction to use for counting
    -0029 % Output:
    -0030 %   model           ecModel
    -0031 %
    -0032 
    -0033 % exrxn must be an exchange rxn and only contain one mets in the equation
    -0034 [~,idx] = ismember(exrxn,model.rxns);
    -0035 EXmets = model.S(:,idx);
    -0036 % find all exchange mets
    -0037 EXmetsIdx = zeros(length(exrxn),1);
    -0038 for k = 1:length(EXmets(1,:))
    -0039     EXmetsIdx(k) = find(EXmets(:,k)); %
    -0040 end
    -0041 EXfors = model.metFormulas(EXmetsIdx);
    -0042 [Ematrix, elements] = getElementalComposition(EXfors,{'C'});
    -0043 Ematrix = Ematrix(:,1);
    -0044 changedmets = exrxn(isnan(Ematrix));
    -0045 Ematrix(isnan(Ematrix)) = 1;
    -0046 CarbonNum = Ematrix;
    -0047 
    -0048 function [Ematrix, elements] = getElementalComposition(formulae, elements, chargeInFormula)
    -0049 % Get the complete elemental composition matrix. It supports formulae with
    -0050 % generic elements, parentheses and decimal places
    -0051 %
    -0052 % USAGE:
    -0053 %    [Ematrix, elements] = getElementalComposition(formulae, elements, chargeInFormula)
    -0054 %
    -0055 % INPUT:
    -0056 %    formulae:        cell array of strings of chemical formulae. Can contain any generic elements starting
    -0057 %                     with a capital letter followed by lowercase letters or '_', followed by a non-negative number.
    -0058 %                     Also support '()', '[]', '{}'. E.g. {'H2O'; '[H2O]2(CuSO4)Generic_element0.5'}
    -0059 % OPTIONAL INPUTS:
    -0060 %    elements:        elements from previous call to preserve the order (default {})
    -0061 %    chargeInFormula: true to accept formulae containing the generic element 'Charge' representing the charges,
    -0062 %                     followed by a real number, e.g., 'HCharge1', 'SO4Charge-2' (default false).
    -0063 %
    -0064 % OUTPUTS:
    -0065 %    Ematrix:         elemental composition matrix (#formulae x #elements)
    -0066 %    elements:         cell array of elements corresponding to the columns of Ematrix
    -0067 %
    -0068 % E.g., [Ematrix, elements] = getElementalComposition({'H2O'; '[H2O]2(CuSO4)Generic_element0.5'}) would return:
    -0069 %  elements = {'H', 'O', 'Cu', 'S', 'Generic_element'}
    -0070 %  Ematrix = [ 2,   1,    0,   0,   0;
    -0071 %              4,   6,    1,   1,   0.5]
    -0072 %
    -0073 % Siu Hung Joshua Chan May 2017
    -0074 
    -0075 if nargin < 3 || isempty(chargeInFormula)
    -0076     chargeInFormula = false;
    -0077 else
    -0078     chargeInFormula = logical(chargeInFormula);
    -0079 end
    -0080 % for recalling the original formula at the top level if there are parentheses
    -0081 % in the formula leading to iterative calling
    -0082 persistent formTopLv
    -0083 persistent formCurLv
    -0084 % for storing error message during iterative calling
    -0085 persistent errMsg
    -0086 persistent errMsgInThisLoop
    -0087 persistent topLvJ
    -0088 persistent selfCall
    -0089 if isempty(selfCall)
    -0090     selfCall = 0;
    -0091 end
    -0092 if ~selfCall
    -0093     [formTopLv, errMsg] = deal('');
    -0094 end
    -0095 
    -0096 if ~isstruct(formulae)
    -0097     if ~iscell(formulae)
    -0098         % make sure it is a cell array of strings
    -0099         formulae = {formulae};
    -0100     end
    -0101 else
    -0102     % also accept COBRA model as input
    -0103     if isfield(formulae, 'metFormulas')
    -0104         formulae = formulae.metFormulas;
    -0105     else
    -0106         error('The 1st input ''formulae'' should be a cell array of strings of formulae or a COBRA model with *.metFormulas')
    -0107     end
    -0108 end
    -0109 
    -0110 if nargin < 2 || isempty(elements)
    -0111     elements = {};
    -0112 elseif numel(unique(elements)) < numel(elements)
    -0113     error('Repeated elements in the input ''elements'' array.')
    -0114 else
    -0115     elements = elements(:)';  % make sure it is a row vector
    -0116 end
    -0117 
    -0118 % the Ematrix
    -0119 Ematrix = zeros(numel(formulae), numel(elements));
    -0120 % replace all brackets and braces by parentheses
    -0121 formulae = regexprep(formulae, '[\[\{]', '\(');
    -0122 formulae = regexprep(formulae, '[\]\}]', '\)');
    -0123 digit = floor(log10(numel(formulae))) + 1;
    -0124 for j = 1:numel(formulae)
    -0125     if ~selfCall
    -0126         % reset top level information for each formula
    -0127         [formTopLv, topLvJ, errMsgInThisLoop] = deal(formulae{j}, j, false);
    -0128     end
    -0129     formulae{j} = strtrim(formulae{j});
    -0130     if ~isempty(formulae{j})
    -0131         % get all outer parentheses
    -0132         parenthesis = [];
    -0133         stP = [];
    -0134         stPpos = [];
    -0135         lv = 0;
    -0136         k = 1;
    -0137         while k <= length(formulae{j})
    -0138             if strcmp(formulae{j}(k),'(')
    -0139                 if lv == 0
    -0140                     pStart = k;
    -0141                 end
    -0142                 lv = lv + 1;
    -0143             elseif strcmp(formulae{j}(k),')')
    -0144                 if lv == 1
    -0145                     parenthesis = [parenthesis; [pStart k]];
    -0146                     % right parenthesis, get the following stoichiometry if any
    -0147                     stPre = regexp(formulae{j}(k+1:end), '^(\+|\-)?\d*\.?\d*', 'match');
    -0148                     if isempty(stPre)
    -0149                         stP = [stP; 1];
    -0150                         stPpos = [stPpos; k k];
    -0151                     else
    -0152                         stCheck = str2double(stPre{1});
    -0153                         s = '';
    -0154                         if isnan(stCheck)
    -0155                             s = 'Invalid';
    -0156                         elseif stCheck < 0
    -0157                             s = 'Negative';
    -0158                         end
    -0159                         if ~isempty(s)  % error if not convertible to number or negative
    -0160                             f = [formulae{j}(parenthesis(end,1):parenthesis(end,2)), stPre{1}];
    -0161                             addErrorMessage(sprintf('    %s stoichiometry in ''%s''\n', s, f))
    -0162                         end
    -0163                         % stoichiometry
    -0164                         stP = [stP; stCheck];
    -0165                         % position of the stoichiometry in the text
    -0166                         stPpos = [stPpos; k + 1, k + length(stPre{1})];
    -0167                         k = k + length(stPre{1});
    -0168                     end
    -0169                 end
    -0170                 lv = lv - 1;
    -0171             end
    -0172             k = k + 1;
    -0173         end
    -0174         if isempty(parenthesis)
    -0175         % No parenthesis, parse the formula
    -0176             re = regexp(formulae{j}, '([A-Z][a-z_]*)((?:\+|\-)?\d*\.?\d*)', 'tokens');
    -0177             s = strjoin(cellfun(@(x) strjoin(x,''), re, 'UniformOutput', false), '');
    -0178             errorFlag = 0;
    -0179             if ~strcmp(s, formulae{j})  % check if the entire formula is retrieved
    -0180                 errorFlag = 1;
    -0181             else
    -0182                 % check the stoichiometry
    -0183                 eleCheck = cellfun(@(x) x{1}, re, 'UniformOutput', false);
    -0184                 stCheck = cellfun(@(x) str2double(x{2}), re);
    -0185                 stCheck(cellfun(@(x) isempty(x{2}), re)) = 1;  % empty value => stoichiometry = 1
    -0186                 if any(isnan(stCheck))
    -0187                     f = strjoin(cellfun(@(x) strjoin(x, ''), re(isnan(stCheck)), 'UniformOutput', false), ''', ''');
    -0188                     [errorFlag, errMsgKey] = deal(2, 'Invalid');
    -0189                 else
    -0190                     % if chargeInFormula is true, detect negative stoich for non-charge elements, else any negative stoich
    -0191                     negSt = (~chargeInFormula | ~strcmp(eleCheck, 'Charge')) & stCheck < 0;
    -0192                     if any(negSt)
    -0193                         f = strjoin(cellfun(@(x) strjoin(x, ''), re(negSt), 'UniformOutput', false), ''', ''');
    -0194                         [errorFlag, errMsgKey] = deal(2, 'Negative');
    -0195                     end
    -0196                 end
    -0197             end
    -0198             if errorFlag > 0
    -0199                 if selfCall <= 1
    -0200                     s2 = sprintf('from the part ''%s''', formulae{j});
    -0201                 elseif selfCall == 2
    -0202                     s2 = sprintf('from the part ''(%s)''', formCurLv);
    -0203                 elseif selfCall == 3
    -0204                     s2 = sprintf('from the part ''(%s)''', formulae{j});
    -0205                 end
    -0206                 if errorFlag == 1
    -0207                     s2 = sprintf(['    Only ''%s'' can be recognized %s.\n'...
    -0208                         '       Each element should start with a capital letter followed by lower case letters'...
    -0209                         ' or ''_'' with indefinite length and followed by a number.\n'], s, s2);
    -0210                 elseif errorFlag == 2
    -0211                     s2 = sprintf('    %s stoichiometry in ''%s'' %s\n', errMsgKey, f, s2);
    -0212                 end
    -0213                 addErrorMessage(s2);
    -0214             end
    -0215             elementJ = repmat({''}, 1, numel(re));
    -0216             nEj = 0;
    -0217             stoichJ = zeros(numel(re),1);
    -0218             for k = 1:numel(re)
    -0219                 [ynK,idK] = ismember(re{k}(1), elementJ(1:nEj));
    -0220                 if ynK
    -0221                     k2 = idK;
    -0222                 else
    -0223                     nEj = nEj + 1;
    -0224                     elementJ{nEj} = re{k}{1};
    -0225                     k2 = nEj;
    -0226                 end
    -0227                 if isempty(re{k}{2})
    -0228                     stoichJ(k2) = stoichJ(k2) + 1;
    -0229                 else
    -0230                     stoichJ(k2) = stoichJ(k2) + str2double(re{k}{2});
    -0231                 end
    -0232             end
    -0233             elementJ = elementJ(1:nEj);
    -0234             stoichJ = stoichJ(1:nEj);
    -0235             [ynE, idE] = ismember(elementJ, elements);  % map to existing elements
    -0236             if any(~ynE)
    -0237                 idE(~ynE) = (numel(elements) + 1):(numel(elements) + sum(~ynE));
    -0238                 Ematrix(:, (numel(elements) + 1):(numel(elements) + sum(~ynE))) = 0;
    -0239                 elements = [elements, elementJ(~ynE)];
    -0240             end
    -0241             Ematrix(j, idE) = stoichJ;
    -0242         else
    -0243             % parentheses found. Iteratively get the formula inside parentheses
    -0244             rest = true(length(formulae{j}),1);
    -0245             for k = 1:size(parenthesis,1)
    -0246                 selfCallCur = selfCall;
    -0247                 selfCall = 3;
    -0248                 [EmatrixK, elements] = getElementalComposition(formulae{j}(...
    -0249                     (parenthesis(k,1)+1):(parenthesis(k,2)-1)), elements, chargeInFormula);
    -0250                 if numel(elements) > size(Ematrix, 2)
    -0251                     Ematrix(:, (size(Ematrix, 2) + 1):numel(elements)) = 0;
    -0252                 end
    -0253                 selfCall = selfCallCur;
    -0254                 Ematrix(j, 1:numel(elements)) = Ematrix(j, 1:numel(elements)) + EmatrixK * stP(k);
    -0255                 rest(parenthesis(k,1):stPpos(k,2)) = false;          
    -0256             end
    -0257             if any(rest)
    -0258                 formCurLv = formulae{j};
    -0259                 selfCallCur = selfCall;
    -0260                 selfCall = 1 + (selfCall >= 1);
    -0261                 while any(rest)
    -0262                     % get the consecutive part of the formula that is not in parentheses
    -0263                     [pStart, pEnd] = deal(find(rest, 1), find(~rest));
    -0264                     pEnd = min(pEnd(pEnd > pStart));
    -0265                     if isempty(pEnd)
    -0266                         pEnd = numel(rest);
    -0267                     else
    -0268                         pEnd = pEnd - 1;
    -0269                     end
    -0270                     [EmatrixK, elements] = getElementalComposition(formulae{j}(pStart:pEnd), elements, chargeInFormula);
    -0271                     if numel(elements) > size(Ematrix, 2)
    -0272                         Ematrix(:, (size(Ematrix, 2) + 1):numel(elements)) = 0;
    -0273                     end
    -0274                     Ematrix(j, 1:numel(elements)) = Ematrix(j, 1:numel(elements)) + EmatrixK;
    -0275                     rest(pStart:pEnd) = false;
    -0276                 end
    -0277                 selfCall = selfCallCur;
    -0278             end
    -0279         end
    -0280     else
    -0281         Ematrix(j,:) = NaN;
    -0282     end
    -0283 end
    -0284 Ematrix = Ematrix(:, 1:numel(elements));
    -0285 if ~selfCall 
    -0286     selfCall = [];
    -0287     if ~isempty(errMsg)
    -0288         error(['%s\n', errMsg], 'Invalid formula input:')
    -0289     end
    -0290 end
    -0291 
    -0292 % nested function for adding error messages
    -0293     function addErrorMessage(s)
    -0294         if ~errMsgInThisLoop
    -0295             errMsg = [errMsg, sprintf(['#%0' num2str(digit) 'd:  %s\n'], topLvJ, formTopLv)];
    -0296             errMsgInThisLoop = true;
    -0297         end
    -0298         errMsg = [errMsg, s];
    -0299     end
    -0300 end
    -0301 
    -0302 end
    -0303 
    -0304 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/bayesianSensitivityTuning.html b/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/bayesianSensitivityTuning.html deleted file mode 100644 index 4c99bbda..00000000 --- a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/bayesianSensitivityTuning.html +++ /dev/null @@ -1,285 +0,0 @@ - - - - Description of bayesianSensitivityTuning - - - - - - - - - -
    Home > src > geckomat > kcat_sensitivity_analysis > Bayesian > bayesianSensitivityTuning.m
    - - - -

    bayesianSensitivityTuning -

    - -

    PURPOSE ^

    -
    bayesianSensitivityTuning
    - -

    SYNOPSIS ^

    -
    function [ecModel, rmseTrace, kcatTrace, stdTrace] = bayesianSensitivityTuning(ecModel,kcatStd,modelAdapter)
    - -

    DESCRIPTION ^

    -
     bayesianSensitivityTuning
    -   Modifies kcats to better fit experimental data. Currently only works with
    -   light models.
    -
    - Input:
    -   ecModel         ecModel that was generated by makeEcModel, or loaded from
    -                   an earlier run. Not compatible with ecModels generated by
    -                   earlier GECKO versions (pre 3.0).
    -   kcatStd         vector of same length as ecModel.ec.kcat, with the
    -                   initial standard deviations (SD) for the kcat values.
    -                   By default, kcatStd is set by multiplying kcat values
    -                   with params.bayesian.initSDmultiplDef, or by source-
    -                   specific multipliers specified in params.bayesian.
    -                   kcatSources and params.bayesian.initSDmultipl. Instead,
    -                   it is also possible to provide a custom kcatStd vector.
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -                   default model adapter).
    -
    - Output:
    -   model           ecModel with new kcats, not applied.
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: - -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function [ecModel, rmseTrace, kcatTrace, stdTrace] = bayesianSensitivityTuning(ecModel,kcatStd,modelAdapter)
    -0002 % bayesianSensitivityTuning
    -0003 %   Modifies kcats to better fit experimental data. Currently only works with
    -0004 %   light models.
    -0005 %
    -0006 % Input:
    -0007 %   ecModel         ecModel that was generated by makeEcModel, or loaded from
    -0008 %                   an earlier run. Not compatible with ecModels generated by
    -0009 %                   earlier GECKO versions (pre 3.0).
    -0010 %   kcatStd         vector of same length as ecModel.ec.kcat, with the
    -0011 %                   initial standard deviations (SD) for the kcat values.
    -0012 %                   By default, kcatStd is set by multiplying kcat values
    -0013 %                   with params.bayesian.initSDmultiplDef, or by source-
    -0014 %                   specific multipliers specified in params.bayesian.
    -0015 %                   kcatSources and params.bayesian.initSDmultipl. Instead,
    -0016 %                   it is also possible to provide a custom kcatStd vector.
    -0017 %   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -0018 %                   default model adapter).
    -0019 %
    -0020 % Output:
    -0021 %   model           ecModel with new kcats, not applied.
    -0022 %
    -0023 if nargin < 3 || isempty(modelAdapter)
    -0024     modelAdapter = ModelAdapterManager.getDefault();
    -0025     if isempty(modelAdapter)
    -0026         error('Either send in a modelAdapter or set the default ecModel adapter in the ModelAdapterManager.')
    -0027     end
    -0028 end
    -0029 
    -0030 %% Load hyperparameters
    -0031 params = modelAdapter.params;
    -0032 initSDmultiplDef    = params.bayesian.initSDmultiplDef;
    -0033 kcatSources         = params.bayesian.kcatSources;
    -0034 initSDmultipl       = params.bayesian.initSDmultipl;
    -0035 scheduleGenerations = params.bayesian.scheduleGenerations;
    -0036 scheduleSamples     = params.bayesian.scheduleSamples;
    -0037 scheduleTarget      = params.bayesian.scheduleTarget;
    -0038 minKeep             = params.bayesian.minKeep;
    -0039 rmseThreshold       = params.bayesian.rmseThreshold;
    -0040 maxGenerations      = params.bayesian.maxGenerations;
    -0041 basePath            = params.path;
    -0042 
    -0043 %% Define initial kcat distributions
    -0044 if nargin < 2 || isempty(kcatStd)
    -0045     kcatStd     = ecModel.ec.kcat .* initSDmultiplDef;
    -0046     for i = 1:numel(kcatSources)
    -0047         selKcats            = strcmpi(ecModel.ec.source,kcatSources{i});
    -0048         kcatStd(selKcats)   = ecModel.ec.kcat(selKcats) .* initSDmultipl(i);
    -0049     end
    -0050 end
    -0051 
    -0052 %% Load data
    -0053 [fluxData, maxGrate, zeroFlux] = loadBayesianData(modelAdapter);
    -0054 
    -0055 % get carbonnum for each exchange rxn to further calculation of error
    -0056 if ~isfield(ecModel,'excarbon')
    -0057     ecModel = addCarbonNum(ecModel);
    -0058     ecModel.excarbon(ecModel.excarbon == 0) = 1;
    -0059 end
    -0060 
    -0061 %these will be updated in the loop below
    -0062 kcats = ecModel.ec.kcat;
    -0063 D     = numel(kcats);
    -0064 
    -0065 rmse = abc_max(ecModel,fluxData,maxGrate,zeroFlux,modelAdapter);
    -0066 fprintf('RMSE with prior kcats: %.2f.\n', rmse)
    -0067 
    -0068 rmseTop   = rmse;
    -0069 kcatTop   = kcats;
    -0070 rmseTrace = rmse;
    -0071 kcatTrace = kcats;
    -0072 stdTrace  = kcatStd;
    -0073 
    -0074 PB1 = ProgressBar2(maxGenerations, ['Run through ' num2str(maxGenerations) ' generations'], 'gui');
    -0075 
    -0076 % Switch off default carbon source, will be set in each sample
    -0077 tmpModel = setParam(ecModel,'lb',modelAdapter.params.c_source,0);
    -0078 
    -0079 %% MAIN ABC-SMC LOOP
    -0080 generation = 1;
    -0081 while rmse > rmseThreshold
    -0082     if generation <= maxGenerations
    -0083         fprintf('Running iteration %d of %d. ', generation, maxGenerations)
    -0084 
    -0085         % Define N and targetFrac dependent on the generation
    -0086         schedulePos = find(generation >= scheduleGenerations, 1, 'last');
    -0087         N           = scheduleSamples(schedulePos);
    -0088         targetFrac  = scheduleTarget(schedulePos); % Acceptance fraction
    -0089 
    -0090         % Sampling
    -0091         if generation == 1
    -0092             % Define randomKcats via lognormal sampling around priors
    -0093             randomKcats = arrayfun(@getrSample, kcats, kcatStd, repmat(N, length(kcats), 1), 'UniformOutput', false);
    -0094             randomKcats = cell2mat(randomKcats);
    -0095         else
    -0096             % Define randomKcats by sampling around previous accepted
    -0097             % solutions using a full-covariance Guassian kernel in log
    -0098             % space, ABC-PMC
    -0099             % Randomly pick N columns with accepted kcat values
    -0100             parent_idx = randi(size(kcatTop,2), [1 N]);
    -0101             parents = log(kcatTop(:, parent_idx));
    -0102 
    -0103             % Compute Cholesky factor of the log-space covariance SigmaLog,
    -0104             % stabilize with 1e-12*i
    -0105             L = chol(SigmaLog + 1e-12*eye(D), 'lower');
    -0106             % Draw normal noise for each proposal and correlate via L
    -0107             Z = randn(D, N);
    -0108             thetaProp = parents + L * Z;
    -0109 
    -0110             % Map back to linear space
    -0111             randomKcats = exp(thetaProp);
    -0112         end
    -0113 
    -0114         if any(randomKcats <= 0, 'all')
    -0115             warning('randomKcats contains non-positive values after sampling; enforcing floor.')
    -0116             randomKcats = max(randomKcats, realmin);
    -0117         end
    -0118 
    -0119         %% Evaluate RMSE for each proposed sample
    -0120         newRmse  = zeros(N,1);
    -0121         PB2 = ProgressBar2(N, ['Simulate ' num2str(N) ' models with random kcats'], 'gui');
    -0122 
    -0123         parfor j = 1:N
    -0124             ecModelIter         = tmpModel;
    -0125             ecModelIter.ec.kcat = randomKcats(:,j);
    -0126             ecModelIter         = applyKcatConstraints(ecModelIter);
    -0127             newRmse(j)          = abc_max(ecModelIter,fluxData,maxGrate,zeroFlux,modelAdapter);
    -0128             count(PB2)
    -0129         end
    -0130 
    -0131         % Leave out zero rmse results: model was unsolvable
    -0132         zeroIdx = (newRmse == 0);
    -0133         newRmse(zeroIdx) = [];
    -0134         randomKcats(:,zeroIdx) = [];
    -0135 
    -0136         % Combine with results from previous generation
    -0137         rmse = [newRmse; rmseTop];
    -0138         kcat = [randomKcats, kcatTop];
    -0139 
    -0140         % Suggested number of accepted samples
    -0141         targetCount = max(1, round(targetFrac * numel(rmse)));
    -0142 
    -0143         % Sort RMSE ascending (best first)
    -0144         [~, ord] = sort(rmse, 'ascend');
    -0145 
    -0146         % Soft guard: check if RMSE curve is flat → soften selection
    -0147         if generation > 5
    -0148             lastWindow = rmseTrace(end-4:end); % Check last 5 RMSE
    -0149             if max(lastWindow) - min(lastWindow) < 1e-6
    -0150                 % Plateau detected → relax selection slightly
    -0151                 targetCount = round(targetCount * 1.3);
    -0152             end
    -0153         end
    -0154 
    -0155         % At least keep minKeep samples
    -0156         targetCount  = max(targetCount, minKeep);
    -0157 
    -0158         % Final accepted indices
    -0159         acc_idx = ord(1:targetCount);
    -0160 
    -0161         % Subset accepted samples
    -0162         rmseTop = rmse(acc_idx);
    -0163         kcatTop = kcat(:, acc_idx);
    -0164 
    -0165         %% Define means and standard deviations from accepted samples
    -0166         ss      = num2cell(kcatTop', 1);
    -0167         [a,b]   = arrayfun(@updateprior, ss);
    -0168         kcats   = transpose(a);
    -0169         kcatStd = transpose(b);
    -0170 
    -0171         %% Build new covariance matrix in log-space, to be used for next sampling
    -0172         thetaAcc = log(kcatTop);
    -0173 
    -0174         % Remove outliers, by filtering out samples whose z-scores had a
    -0175         % Median Absolute Deviation (MAD) of 6 or more
    -0176         z = abs(thetaAcc - median(thetaAcc,2)) ./ (mad(thetaAcc,1,2) + 1e-12);
    -0177         keepMask = median(z,1) < 6;
    -0178         % Fallback if everything gets filtered away
    -0179         if ~any(keepMask)
    -0180             warning('MAD filter removed all samples; disabling filtering this generation.');
    -0181             keepMask = true(1, size(thetaAcc,2));
    -0182         end
    -0183         thetaClean = thetaAcc(:, keepMask);
    -0184 
    -0185         % Determine empirical covariance of samples who were retained
    -0186         Cemp = cov(thetaClean');
    -0187 
    -0188         % Reduce noise in Cemp, through Ledoit-Wolf shrinkage towards a
    -0189         % diagonal covariance
    -0190         alphaLW = 0.1;
    -0191         SigmaLog = (1 - alphaLW) * Cemp + alphaLW * diag(diag(Cemp));
    -0192 
    -0193         %% Track progress (use best, not first)
    -0194         [bestRMSE, bestIdx] = min(rmseTop);
    -0195         rmseTrace = [rmseTrace, bestRMSE];
    -0196         kcatTrace = [kcatTrace, kcats];
    -0197         stdTrace  = [stdTrace,  kcatStd];
    -0198 
    -0199         % Set a feasible/best point for next iteration's model baseline
    -0200         tmpModel.ec.kcat = kcatTop(:, bestIdx);
    -0201         tmpModel = applyKcatConstraints(tmpModel);
    -0202 
    -0203         fprintf('Accepted %d / %d, avg RMSE (accepted): %.2f, best: %.2f.\n', ...
    -0204             numel(rmseTop), numel(rmse), mean(rmseTop), bestRMSE)
    -0205 
    -0206         generation = generation + 1;
    -0207     else
    -0208         fprintf('Halted due to reaching maximum generation limit. Returning best posterior kcats.\n')
    -0209         break
    -0210     end
    -0211     count(PB1)
    -0212 end
    -0213 
    -0214 % Return best posterior kcats (best among last accepted)
    -0215 [~, bestIdx] = min(rmseTop);
    -0216 ecModel.ec.kcat = kcatTop(:, bestIdx);
    -0217 ecModel = applyKcatConstraints(ecModel);
    -0218 fprintf('Final RMSE: %.2f.\n', rmseTop(bestIdx))
    -0219 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/getrSample.html b/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/getrSample.html deleted file mode 100644 index 9cd7ec41..00000000 --- a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/getrSample.html +++ /dev/null @@ -1,93 +0,0 @@ - - - - Description of getrSample - - - - - - - - - - - - - -

    getrSample -

    - -

    PURPOSE ^

    -
    getrSample
    - -

    SYNOPSIS ^

    -
    function r = getrSample(mu,sigma,n,method)
    - -

    DESCRIPTION ^

    -
     getrSample
    -   Sample random kcat values from a distribution.
    -
    - Input:
    -   mu      mean of distribution
    -   sigma   standard deviation of distribution
    -   n       number of kcat values to sample
    -   method  shape of distribution: 'lognormal' or 'uniform'. (optional,
    -           default is 'lognormal'). If 'lognormal' is selected, mu and
    -           sigma are automatically converted into log-space
    -
    - Output:
    -   r       sample of kcat values
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: - - - - - -

    SOURCE CODE ^

    -
    0001 function r = getrSample(mu,sigma,n,method)
    -0002 % getrSample
    -0003 %   Sample random kcat values from a distribution.
    -0004 %
    -0005 % Input:
    -0006 %   mu      mean of distribution
    -0007 %   sigma   standard deviation of distribution
    -0008 %   n       number of kcat values to sample
    -0009 %   method  shape of distribution: 'lognormal' or 'uniform'. (optional,
    -0010 %           default is 'lognormal'). If 'lognormal' is selected, mu and
    -0011 %           sigma are automatically converted into log-space
    -0012 %
    -0013 % Output:
    -0014 %   r       sample of kcat values
    -0015 
    -0016 if nargin < 4
    -0017     method = 'lognormal';
    -0018 end
    -0019 if mu == 0
    -0020     r = zeros(1,n);
    -0021 elseif strcmp(method,'lognormal')
    -0022     % Convert to log-space
    -0023     varLog      = log(1 + (sigma/mu)^2);
    -0024     sigmaLog    = sqrt(varLog);
    -0025     muLog       = log(mu) - 0.5 * varLog;
    -0026 
    -0027     % Take random samples from lognormal distribution
    -0028     r = lognrnd(muLog,sigmaLog,[1,n]);
    -0029 elseif strcmp(method,'uniform')
    -0030     pd = makedist('uniform','lower',mu - sigma,'upper',mu + sigma);
    -0031     t = truncate(pd,0,inf);
    -0032     r = random(t,1,n);
    -0033 end
    -0034 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/index.html b/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/index.html deleted file mode 100644 index de423a24..00000000 --- a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/index.html +++ /dev/null @@ -1,29 +0,0 @@ - - - - Index for Directory src\geckomat\kcat_sensitivity_analysis\Bayesian - - - - - - - - - - -
    < Master indexIndex for src\geckomat\kcat_sensitivity_analysis\Bayesian >
    - -

    Index for src\geckomat\kcat_sensitivity_analysis\Bayesian

    - -

    Matlab files in this directory:

    - -
     abc_maxabc_max
     addCarbonNumaddCarbonNum
     bayesianSensitivityTuningbayesianSensitivityTuning
     getrSamplegetrSample
     loadBayesianData
     mse
     updatepriorupdateprior
    - - - - -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/loadBayesianData.html b/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/loadBayesianData.html deleted file mode 100644 index 03cb384a..00000000 --- a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/loadBayesianData.html +++ /dev/null @@ -1,63 +0,0 @@ - - - - Description of loadBayesianData - - - - - - - - - -
    Home > src > geckomat > kcat_sensitivity_analysis > Bayesian > loadBayesianData.m
    - - - -

    loadBayesianData -

    - -

    PURPOSE ^

    -
    - -

    SYNOPSIS ^

    -
    function [fluxData, maxGrate, zeroFlux] = loadBayesianData(modelAdapter)
    - -

    DESCRIPTION ^

    -
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: - - - - - -

    SOURCE CODE ^

    -
    0001 function [fluxData, maxGrate, zeroFlux] = loadBayesianData(modelAdapter)
    -0002 
    -0003 if nargin < 1 || isempty(modelAdapter)
    -0004     modelAdapter = ModelAdapterManager.getDefault();
    -0005     if isempty(modelAdapter)
    -0006         error('Either send in a modelAdapter or set the default ecModel adapter in the ModelAdapterManager.')
    -0007     end
    -0008 end
    -0009 
    -0010 basePath            = modelAdapter.params.path;
    -0011 fluxData = loadFluxData(fullfile(basePath,'data','bayesianFluxData.tsv'));
    -0012 fluxData.biomass = modelAdapter.params.bioRxn;
    -0013 maxGrate = loadFluxData(fullfile(basePath,'data','bayesianMaxGrowth.tsv'));
    -0014 maxGrate.biomass = modelAdapter.params.bioRxn;
    -0015 zeroFlux = table2cell(readtable(fullfile(basePath,'data','bayesianZeroExch.tsv'), 'Delimiter', '\t', 'FileType','delimitedtext'));
    -0016 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/mse.html b/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/mse.html deleted file mode 100644 index c13adfa2..00000000 --- a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/mse.html +++ /dev/null @@ -1,50 +0,0 @@ - - - - Description of mse - - - - - - - - - - - - - -

    mse -

    - -

    PURPOSE ^

    -
    - -

    SYNOPSIS ^

    -
    function err = mse(y,x)
    - -

    DESCRIPTION ^

    -
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: - - - - - -

    SOURCE CODE ^

    -
    0001 function err = mse(y,x)
    -0002 err = (norm(x(:)-y(:),2).^2)/numel(x);
    -0003 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/updateprior.html b/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/updateprior.html deleted file mode 100644 index d0ec2b98..00000000 --- a/doc/src/geckomat/kcat_sensitivity_analysis/Bayesian/updateprior.html +++ /dev/null @@ -1,91 +0,0 @@ - - - - Description of updateprior - - - - - - - - - - - - - -

    updateprior -

    - -

    PURPOSE ^

    -
    updateprior
    - -

    SYNOPSIS ^

    -
    function [mu,sigma] = updateprior(x,defaultCV)
    - -

    DESCRIPTION ^

    -
     updateprior
    -   Calculates a new distribution from the provided kcat values
    -
    - Input:
    -   x       kcat values
    -
    - Output:
    -   mu      mean
    -   sigma   standard deviation
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: - - - - - -

    SOURCE CODE ^

    -
    0001 function [mu,sigma] = updateprior(x,defaultCV)
    -0002 % updateprior
    -0003 %   Calculates a new distribution from the provided kcat values
    -0004 %
    -0005 % Input:
    -0006 %   x       kcat values
    -0007 %
    -0008 % Output:
    -0009 %   mu      mean
    -0010 %   sigma   standard deviation
    -0011 
    -0012 if nargin<2
    -0013     defaultCV = 0.25;
    -0014 end
    -0015 
    -0016 if iscell(x), x = x{:}; end
    -0017 
    -0018 % Remove non-positive values—they cannot be logged
    -0019 n_before = numel(x);
    -0020 x = x(x > 0);
    -0021 if isempty(x)
    -0022     error('x cannot be empty or contain only non-positive values.');
    -0023 end
    -0024 if numel(x) < n_before
    -0025     warning('Removed %d non-positive values before fitting.', n_before - numel(x));
    -0026 end
    -0027 
    -0028 if isscalar(x)
    -0029     mu      = x;
    -0030     sigma   = x * defaultCV;
    -0031 else
    -0032     pd      = fitdist(log(x),'normal');
    -0033     mu    = exp(pd.mu + 0.5 * pd.sigma^2);
    -0034     sigma = sqrt( (exp(pd.sigma^2) - 1) * exp(2*pd.mu + pd.sigma^2) );
    -0035 end
    -0036 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/kcat_sensitivity_analysis/findMaxValue.html b/doc/src/geckomat/kcat_sensitivity_analysis/findMaxValue.html deleted file mode 100644 index 45bd3106..00000000 --- a/doc/src/geckomat/kcat_sensitivity_analysis/findMaxValue.html +++ /dev/null @@ -1,124 +0,0 @@ - - - - Description of findMaxValue - - - - - - - - - - - - - -

    findMaxValue -

    - -

    PURPOSE ^

    -
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    - -

    SYNOPSIS ^

    -
    function [value,organism,parameter] = findMaxValue(EC_cell,BRENDA,SA_cell)
    - -

    DESCRIPTION ^

    -
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -function [value,organism,parameter] = findMaxValue(EC_cell,BRENDA, SA_cell)
    -
    - Function that gets the maximum kinetic parameter (Kcat or S.A.*Mw) from 
    - the BRENDA files for the specified set of EC numbers. The algorithm also 
    - returns the organism and the parameter type (Kcat or S.A.) of the query.
    -
    - Ivan Domenzain    Last edited. 2018-02-06
    -%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -Looks for the maximum turnover number available for the EC# associated
    -with the uniprot code
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0002 %function [value,organism,parameter] = findMaxValue(EC_cell,BRENDA, SA_cell)
    -0003 %
    -0004 % Function that gets the maximum kinetic parameter (Kcat or S.A.*Mw) from
    -0005 % the BRENDA files for the specified set of EC numbers. The algorithm also
    -0006 % returns the organism and the parameter type (Kcat or S.A.) of the query.
    -0007 %
    -0008 % Ivan Domenzain    Last edited. 2018-02-06
    -0009 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0010 function [value,organism,parameter] = findMaxValue(EC_cell,BRENDA,SA_cell)
    -0011     %Looks for the maximum turnover number available for the EC# associated
    -0012     %with the uniprot code
    -0013     EC_cell    = strsplit(EC_cell,' ');
    -0014     value      = [];
    -0015     organism   = [];
    -0016     parameter  = [];
    -0017     for i=1:length(EC_cell)
    -0018         find_flag  = false;
    -0019         %In case that wild cards are present in the EC number the search on
    -0020         %the BRENDA file will be relaxed.
    -0021         if ~isempty(strfind(EC_cell{i},'-'))
    -0022              EC_cell{i} = EC_cell{i}(strfind(EC_cell{i},'-')-1:end);
    -0023              find_flag  = true;
    -0024         end    
    -0025         ECnumber = ['EC' EC_cell{i}];
    -0026         Kcat     = 0; orgK = '';
    -0027         if find_flag == true
    -0028             matching = find(~cellfun(@isempty,strfind(BRENDA{1},ECnumber)));
    -0029         else
    -0030             % If no wild cards are present the EC number search in the
    -0031             % BRENDA file will look for an exact match
    -0032             matching = find(strcmpi(ECnumber,BRENDA{1}));
    -0033         end
    -0034         %Gets the maximum Kcat value for the queried EC#
    -0035         if ~isempty(matching)
    -0036             [Kcat, maxIndx] = max(BRENDA{4}(matching));
    -0037             orgK            = BRENDA{3}(matching(maxIndx));
    -0038         end        
    -0039         % Looks for the maximum SA*Mw value available for the EC number
    -0040         SA_Mw = 0; orgS = '';
    -0041         if find_flag == true
    -0042             matching = find(~cellfun(@isempty,strfind(SA_cell{1},ECnumber)));
    -0043         else
    -0044             matching = find(strcmpi(ECnumber,SA_cell{1}));
    -0045         end
    -0046         %Gets the maximum SA*Mw value for the queried EC#
    -0047         if ~isempty(matching)
    -0048             [SA_Mw, maxIndx] = max(SA_cell{3}(matching));
    -0049             SA_Mw            = SA_Mw; %[1/hr]
    -0050             orgS             = SA_cell{2}(matching(maxIndx));
    -0051         end        
    -0052         %Choose the maximal available value as a turnover number for the EC
    -0053         value  = [value; max(Kcat,SA_Mw)]; 
    -0054 
    -0055         if Kcat>SA_Mw
    -0056             organism  = [organism; {orgK}];
    -0057             parameter = [parameter; {'K_cat'}];
    -0058         else
    -0059             organism  = [organism; {orgS}];
    -0060             parameter = [parameter; {'SA*Mw'}];
    -0061         end   
    -0062     end
    -0063     [value, maxIndx] = max(value);
    -0064     organism         = organism(maxIndx);
    -0065     parameter        = parameter(maxIndx);
    -0066 end
    -0067 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/kcat_sensitivity_analysis/index.html b/doc/src/geckomat/kcat_sensitivity_analysis/index.html deleted file mode 100644 index 332553fc..00000000 --- a/doc/src/geckomat/kcat_sensitivity_analysis/index.html +++ /dev/null @@ -1,31 +0,0 @@ - - - - Index for Directory src\geckomat\kcat_sensitivity_analysis - - - - - - - - - - -
    < Master indexIndex for src\geckomat\kcat_sensitivity_analysis >
    - -

    Index for src\geckomat\kcat_sensitivity_analysis

    - -

    Matlab files in this directory:

    - -
     findMaxValue%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
     sensitivityTuningsensitivityTuning
     sigmaFittersigmaFitter
     truncateValues%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    - - -

    Subsequent directories:

    - - -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/kcat_sensitivity_analysis/sensitivityTuning.html b/doc/src/geckomat/kcat_sensitivity_analysis/sensitivityTuning.html deleted file mode 100644 index 93a4112f..00000000 --- a/doc/src/geckomat/kcat_sensitivity_analysis/sensitivityTuning.html +++ /dev/null @@ -1,247 +0,0 @@ - - - - Description of sensitivityTuning - - - - - - - - - -
    Home > src > geckomat > kcat_sensitivity_analysis > sensitivityTuning.m
    - - - -

    sensitivityTuning -

    - -

    PURPOSE ^

    -
    sensitivityTuning
    - -

    SYNOPSIS ^

    -
    function [model, tunedKcats] = sensitivityTuning(model, desiredGrowthRate, modelAdapter, foldChange, protToIgnore, verbose)
    - -

    DESCRIPTION ^

    -
     sensitivityTuning
    -    Function that relaxes the most limiting kcats until a certain growth rate
    -    is reached. The function will update kcats in model.ec.kcat.
    -
    - Input:
    -   model              an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   desiredGrowthRate  kcats will be relaxed until this growth rate is reached
    -   modelAdapter       a loaded model adapter (Optional, will otherwise use the
    -                      default model adapter).
    -   foldChange         kcat values will be increased by this fold-change.
    -                      (Opt, default 10)
    -   protToIgnore       vector of protein ids to be ignore in tuned kcats.
    -                      e.g. {'P38122', 'Q99271'} (Optional, default = [])
    -   verbose            logical whether progress should be reported (Optional,
    -                      default true)
    -
    - Output:
    -   model              ecModel with updated model.ec.kcat
    -   tunedKcats         structure with information on tuned kcat values
    -                      rxns     identifiers of reactions with tuned kcat
    -                               values
    -                      rxnNames names of the reactions in tunedKcats.rxns
    -                      enzymes  enzymes that catalyze the reactions in
    -                               tunedKcats.rxns, whose kcat value has been
    -                               tuned.
    -                      oldKcat  kcat values in the input model
    -                      newKcat  kcat values in the output model, after tuning
    -
    - Note: The model.ec.notes field will contain the original kcat value and
    - source, unless the kcat has previously been set by sensitivityTuning, in
    - which case the notes field remains unchanged.
    -
    - Usage:
    -   [model, tunedKcats] = sensitivityTuning(model, desiredGrowthRate, modelAdapter, foldChange, protToIgnore, verbose)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function [model, tunedKcats] = sensitivityTuning(model, desiredGrowthRate, modelAdapter, foldChange, protToIgnore, verbose)
    -0002 % sensitivityTuning
    -0003 %    Function that relaxes the most limiting kcats until a certain growth rate
    -0004 %    is reached. The function will update kcats in model.ec.kcat.
    -0005 %
    -0006 % Input:
    -0007 %   model              an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0008 %   desiredGrowthRate  kcats will be relaxed until this growth rate is reached
    -0009 %   modelAdapter       a loaded model adapter (Optional, will otherwise use the
    -0010 %                      default model adapter).
    -0011 %   foldChange         kcat values will be increased by this fold-change.
    -0012 %                      (Opt, default 10)
    -0013 %   protToIgnore       vector of protein ids to be ignore in tuned kcats.
    -0014 %                      e.g. {'P38122', 'Q99271'} (Optional, default = [])
    -0015 %   verbose            logical whether progress should be reported (Optional,
    -0016 %                      default true)
    -0017 %
    -0018 % Output:
    -0019 %   model              ecModel with updated model.ec.kcat
    -0020 %   tunedKcats         structure with information on tuned kcat values
    -0021 %                      rxns     identifiers of reactions with tuned kcat
    -0022 %                               values
    -0023 %                      rxnNames names of the reactions in tunedKcats.rxns
    -0024 %                      enzymes  enzymes that catalyze the reactions in
    -0025 %                               tunedKcats.rxns, whose kcat value has been
    -0026 %                               tuned.
    -0027 %                      oldKcat  kcat values in the input model
    -0028 %                      newKcat  kcat values in the output model, after tuning
    -0029 %
    -0030 % Note: The model.ec.notes field will contain the original kcat value and
    -0031 % source, unless the kcat has previously been set by sensitivityTuning, in
    -0032 % which case the notes field remains unchanged.
    -0033 %
    -0034 % Usage:
    -0035 %   [model, tunedKcats] = sensitivityTuning(model, desiredGrowthRate, modelAdapter, foldChange, protToIgnore, verbose)
    -0036 
    -0037 if nargin < 6 || isempty(verbose)
    -0038     verbose = true;
    -0039 end
    -0040 if nargin < 5 || isempty(protToIgnore)
    -0041     protToIgnore = {};
    -0042 end
    -0043 if nargin < 4 || isempty(foldChange)
    -0044     foldChange = 10;
    -0045 end
    -0046 if nargin < 3 || isempty(modelAdapter)
    -0047     modelAdapter = ModelAdapterManager.getDefault();
    -0048     if isempty(modelAdapter)
    -0049         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0050     end
    -0051 end
    -0052 params = modelAdapter.params;
    -0053 if nargin < 2 || isempty(desiredGrowthRate)
    -0054     desiredGrowthRate = params.gR_exp;
    -0055 end
    -0056 
    -0057 kcatList = [];
    -0058 m = model;
    -0059 m.c = double(strcmp(m.rxns, params.bioRxn));% Make sure that growth is maximized
    -0060 
    -0061 [res,hs] = solveLP(m);
    -0062 if isempty(res.x)
    -0063     error('FBA of input model gives no valid result. Reduce protein pool constraint with setProtPoolSize and/or check if exchange constraints are correctly defined.')
    -0064 end
    -0065 lastGrowth = 0;
    -0066 if ~m.ec.geckoLight
    -0067     %for the full model, we first find the draw reaction with the most flux
    -0068     drawRxns = startsWith(m.rxns, 'usage_prot_');
    -0069     idxToIgnore = cellfun(@(x) find(strcmpi(model.rxns, ['usage_prot_' x])), protToIgnore);
    -0070     iteration = 1;
    -0071     while true
    -0072         [res,hs] = solveLP(m,0,[],hs); %skip parsimonius, only takes time
    -0073         if (lastGrowth == res.f)
    -0074             printOrange('WARNING: No growth increase from increased kcats - check if the constraints on the uptake reactions are too tight.\n');
    -0075             break;
    -0076         end
    -0077         lastGrowth = res.f;
    -0078         if verbose; disp(['Iteration ' num2str(iteration) ': Growth: ' num2str(lastGrowth)]); end
    -0079         if (lastGrowth >= desiredGrowthRate)
    -0080             break;
    -0081         end
    -0082         %If you get an error here, it is likely due to numerical issues in the solver
    -0083         %The trick where we don't allow low kcats is to fix that, but maybe
    -0084         %it is not enough.
    -0085         iteration            = iteration + 1;
    -0086         %find the highest draw_prot rxn flux
    -0087         drawFluxes           = zeros(length(drawRxns),1);
    -0088         drawFluxes(drawRxns) = res.x(drawRxns);
    -0089         % Remove from the list user defined proteins
    -0090         drawFluxes(idxToIgnore) = 0;
    -0091         [~,sel]              = min(drawFluxes); % since bounds -1000 to 0
    -0092         %Now get the metabolite
    -0093         metSel               = m.S(:,sel) < 0; % negative coeff
    -0094         %now find the reaction with the largest consumption of this protein
    -0095         protFluxes           = m.S(metSel,:).' .* res.x; %negative
    -0096         [~,rxnSel]           = min(protFluxes);
    -0097         kcatList             = [kcatList, rxnSel];
    -0098         rxn                  = m.rxns(rxnSel);
    -0099         targetSubRxn         = strcmp(m.ec.rxns, rxn);
    -0100         if ~strcmp(m.ec.source(targetSubRxn),'sensitivityTuning')
    -0101             oldNote          = m.ec.notes{targetSubRxn};
    -0102             newNote          = ['preTuneKcat=' num2str(m.ec.kcat(targetSubRxn)) ' | source:' m.ec.source{targetSubRxn}];
    -0103             if ~isempty(oldNote)
    -0104                 newNote      = [oldNote '; ' newNote];
    -0105             end
    -0106             m.ec.notes{targetSubRxn}    = newNote;
    -0107         end
    -0108         m.ec.kcat(targetSubRxn)     = m.ec.kcat(targetSubRxn) .* foldChange;
    -0109         m.ec.source(targetSubRxn)   = {'sensitivityTuning'};
    -0110         m                    = applyKcatConstraints(m,targetSubRxn);
    -0111     end
    -0112 
    -0113 else
    -0114     origRxns = extractAfter(m.ec.rxns,4);
    -0115     %find the reactions involved in proteins to be ignored
    -0116     idxToIgnore = cellfun(@(x) find(m.ec.rxnEnzMat(:, strcmpi(m.ec.enzymes, x))), protToIgnore, 'UniformOutput', false);
    -0117     %create an unique vector
    -0118     idxToIgnore = unique(cat(1, idxToIgnore{:}));
    -0119     %get the correct idx in model.rxns
    -0120     idxToIgnore = cellfun(@(x) find(strcmpi(m.rxns, x)), origRxns(idxToIgnore));
    -0121     iteration = 1;
    -0122     while true
    -0123         res = solveLP(m,0); %skip parsimonius, only takes time
    -0124         if (lastGrowth == res.f)
    -0125             printOrange('No growth increase from increased kcats - check if the constraints on the uptake reactions are too tight.\n');
    -0126             break;
    -0127         end
    -0128         lastGrowth = res.f;
    -0129         if (lastGrowth >= desiredGrowthRate)
    -0130             break;
    -0131         end
    -0132         %If you get an error here, it is likely due to numerical issues in the solver
    -0133         %The trick where we don't allow low kcats is to fix that, but maybe
    -0134         %it is not enough.
    -0135         if verbose; disp(['Iteration ' num2str(iteration) ': Growth: ' num2str(lastGrowth)]); end
    -0136         iteration       = iteration + 1;
    -0137         %find the highest protein usage flux
    -0138         protPoolStoich  = m.S(strcmp(m.mets, 'prot_pool'),:).';
    -0139         protPoolStoich(idxToIgnore) = 0;
    -0140         [~,sel]         = min(res.x .* protPoolStoich); %max consumption
    -0141         kcatList        = [kcatList, sel];
    -0142         rxn             = m.rxns(sel.');
    -0143         targetSubRxns   = strcmp(origRxns, rxn);
    -0144         m.ec.kcat(targetSubRxns) = m.ec.kcat(targetSubRxns) .* foldChange;
    -0145         m               = applyKcatConstraints(m,rxn);
    -0146     end
    -0147 end
    -0148 
    -0149 kcatList        = unique(kcatList);
    -0150 tunedKcats.rxns = m.rxns(kcatList);
    -0151 tunedKcats.rxnNames = m.rxnNames(kcatList);
    -0152 if ~model.ec.geckoLight
    -0153     [~, rxnIdx]     = ismember(tunedKcats.rxns,m.ec.rxns);
    -0154 else
    -0155     [~, rxnIdx]     = ismember(tunedKcats.rxns,origRxns);
    -0156 end
    -0157 tunedKcats.enzymes  = cell(numel(kcatList),1);
    -0158 for i=1:numel(rxnIdx)
    -0159     [~, metIdx]     = find(m.ec.rxnEnzMat(rxnIdx(i),:));
    -0160     tunedKcats.enzymes{i}   = strjoin(m.ec.enzymes(metIdx),';');
    -0161 end
    -0162 tunedKcats.oldKcat  = model.ec.kcat(rxnIdx);
    -0163 tunedKcats.newKcat  = m.ec.kcat(rxnIdx);
    -0164 tunedKcats.source   = model.ec.source(rxnIdx);
    -0165 
    -0166 model = m;
    -0167 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/kcat_sensitivity_analysis/sigmaFitter.html b/doc/src/geckomat/kcat_sensitivity_analysis/sigmaFitter.html deleted file mode 100644 index 91e68124..00000000 --- a/doc/src/geckomat/kcat_sensitivity_analysis/sigmaFitter.html +++ /dev/null @@ -1,158 +0,0 @@ - - - - Description of sigmaFitter - - - - - - - - - - - - - -

    sigmaFitter -

    - -

    PURPOSE ^

    -
    sigmaFitter
    - -

    SYNOPSIS ^

    -
    function [model, sigma] = sigmaFitter(model, growthRate, Ptot, f, makePlot, modelAdapter)
    - -

    DESCRIPTION ^

    -
     sigmaFitter
    -   Function that fits the average enzyme saturation factor in an ecModel
    -   according to a provided experimentally measured value for the objective
    -   function (i.e. growth rate at specified conditions)
    -
    - INPUTS:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   growthRate      growth rate that should be reached. If not
    -                   specified, the value will be read from the model
    -                   adapter.
    -   Ptot            Total cellular protein content in g/gDCW. If not
    -                   specified, the value will be read from the model
    -                   adapter. If not specified in model adapter, 0.5 g/gDCW
    -                   is assumed.
    -   f               Estimated fraction of enzymes in the model. If not
    -                   specified, the value will be read from the model
    -                   adapter. If not specified in model adapter, 0.5 is
    -                   assumed.
    -   makePlot        Logical whether a plot should be made. Default true.
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -                   default model adapter).
    -
    - Output:
    -   model           ecModel with protein pool exchange upper bound adapted
    -                   to the optimal sigma-factor
    -   sigma           optimal sigma-factor
    -
    - Usage:
    -   [model, sigma] = sigmaFitter(model, growthRate, Ptot, f, makePlot, modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function [model, sigma] = sigmaFitter(model, growthRate, Ptot, f, makePlot, modelAdapter)
    -0002 % sigmaFitter
    -0003 %   Function that fits the average enzyme saturation factor in an ecModel
    -0004 %   according to a provided experimentally measured value for the objective
    -0005 %   function (i.e. growth rate at specified conditions)
    -0006 %
    -0007 % INPUTS:
    -0008 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0009 %   growthRate      growth rate that should be reached. If not
    -0010 %                   specified, the value will be read from the model
    -0011 %                   adapter.
    -0012 %   Ptot            Total cellular protein content in g/gDCW. If not
    -0013 %                   specified, the value will be read from the model
    -0014 %                   adapter. If not specified in model adapter, 0.5 g/gDCW
    -0015 %                   is assumed.
    -0016 %   f               Estimated fraction of enzymes in the model. If not
    -0017 %                   specified, the value will be read from the model
    -0018 %                   adapter. If not specified in model adapter, 0.5 is
    -0019 %                   assumed.
    -0020 %   makePlot        Logical whether a plot should be made. Default true.
    -0021 %   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -0022 %                   default model adapter).
    -0023 %
    -0024 % Output:
    -0025 %   model           ecModel with protein pool exchange upper bound adapted
    -0026 %                   to the optimal sigma-factor
    -0027 %   sigma           optimal sigma-factor
    -0028 %
    -0029 % Usage:
    -0030 %   [model, sigma] = sigmaFitter(model, growthRate, Ptot, f, makePlot, modelAdapter)
    -0031 
    -0032 if nargin < 6 || isempty(modelAdapter)
    -0033     modelAdapter = ModelAdapterManager.getDefault();
    -0034     if isempty(modelAdapter)
    -0035         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0036     end
    -0037 end
    -0038 
    -0039 if nargin<5 || isempty(makePlot)
    -0040     makePlot = true;
    -0041 end
    -0042 if nargin<4 || isempty(f)
    -0043     f = modelAdapter.getParameters().f;
    -0044 end
    -0045 if nargin<3 || isempty(Ptot)
    -0046     Ptot = modelAdapter.getParameters().Ptot;
    -0047 end
    -0048 if nargin<2 || isempty(growthRate)
    -0049     growthRate = modelAdapter.getParameters().gR_exp;
    -0050 end
    -0051 
    -0052 objValues = [];
    -0053 errors    = [];
    -0054 sigParam  = [];
    -0055 objPos    = find(model.c);
    -0056 %Relax bounds for the objective function
    -0057 model.lb(objPos) = 0;
    -0058 model.ub(objPos) = 1000;
    -0059 hsSol=[];
    -0060 for i=1:100
    -0061     %Constrains the ecModel with the i-th sigma factor
    -0062     sigma = i/100;
    -0063     model = setProtPoolSize(model, Ptot, f, sigma, modelAdapter);
    -0064     [solution, hsSol]  = solveLP(model,0,[],hsSol);
    -0065     if isempty(solution.x)
    -0066         solution.x=zeros(length(model.rxns),1);
    -0067     end
    -0068     objValues = [objValues; solution.x(objPos)];
    -0069     error     = abs(((growthRate-solution.x(objPos))/growthRate)*100);
    -0070     errors    = [errors; error];
    -0071     error     = num2str(((growthRate-solution.x(objPos))/growthRate)*100);
    -0072     sigParam  = [sigParam; sigma];
    -0073 end
    -0074 [~, minIndx] = min(errors);
    -0075 sigma     = sigParam(minIndx);
    -0076 if makePlot
    -0077     figure
    -0078     plot(sigParam,errors,'LineWidth',5)
    -0079     title('Sigma fitting')
    -0080     xlabel('Average enzyme saturation [-]')
    -0081     ylabel('Absolute relative error [%]')
    -0082 end
    -0083 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/kcat_sensitivity_analysis/truncateValues.html b/doc/src/geckomat/kcat_sensitivity_analysis/truncateValues.html deleted file mode 100644 index f549a94f..00000000 --- a/doc/src/geckomat/kcat_sensitivity_analysis/truncateValues.html +++ /dev/null @@ -1,76 +0,0 @@ - - - - Description of truncateValues - - - - - - - - - -
    Home > src > geckomat > kcat_sensitivity_analysis > truncateValues.m
    - - - -

    truncateValues -

    - -

    PURPOSE ^

    -
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    - -

    SYNOPSIS ^

    -
    function table = truncateValues(table,cols)
    - -

    DESCRIPTION ^

    -
    %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    - table = truncateValues(table,cols)
    -   table   cell array or table where some columns have values that should
    -           be truncated
    -   cols    index or indices of columns with values to be truncated
    -
    - Benjamin Sanchez    Last edited: 2018-05-25
    - Eduard Kerkhoven    Last edited: 2018-12-05
    -%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0002 % table = truncateValues(table,cols)
    -0003 %   table   cell array or table where some columns have values that should
    -0004 %           be truncated
    -0005 %   cols    index or indices of columns with values to be truncated
    -0006 %
    -0007 % Benjamin Sanchez    Last edited: 2018-05-25
    -0008 % Eduard Kerkhoven    Last edited: 2018-12-05
    -0009 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -0010 function table = truncateValues(table,cols)
    -0011 
    -0012 [m,n] = size(table);
    -0013 for i = 1:m
    -0014     for j = cols
    -0015         orderMagn  = max([ceil(log10(abs(table{i,j}))),0]);
    -0016         table{i,j} = round(table{i,j},6-orderMagn);
    -0017     end
    -0018 end
    -0019 end
    -0020 
    -0021 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/limit_proteins/calculateFfactor.html b/doc/src/geckomat/limit_proteins/calculateFfactor.html deleted file mode 100644 index ae81fe1d..00000000 --- a/doc/src/geckomat/limit_proteins/calculateFfactor.html +++ /dev/null @@ -1,143 +0,0 @@ - - - - Description of calculateFfactor - - - - - - - - - -
    Home > src > geckomat > limit_proteins > calculateFfactor.m
    - - - -

    calculateFfactor -

    - -

    PURPOSE ^

    -
    calculateFfactor
    - -

    SYNOPSIS ^

    -
    function f = calculateFfactor(model, protData, enzymes, modelAdapter)
    - -

    DESCRIPTION ^

    -
     calculateFfactor
    -   Computes the f factor, as a proxy to the mass fraction of proteins
    -   accounted for in an ecModel out of the total protein content in cells.
    -
    - Input:
    -   model        an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   protData     structure with proteome data, from loadProtData (Optional,
    -                by default it instead attempts to load data/paxDB.tsv)
    -   enzymes      list of enzymes (Optional, default model.ec.enzymes)
    -   modelAdapter a loaded model adapter (Optional, will otherwise use the
    -                default model adapter).
    -
    - Output:
    -   f            f-factor
    -
    - Usage:
    -   f = calculateFfactor(model, protData, enzymes, modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function f = calculateFfactor(model, protData, enzymes, modelAdapter)
    -0002 % calculateFfactor
    -0003 %   Computes the f factor, as a proxy to the mass fraction of proteins
    -0004 %   accounted for in an ecModel out of the total protein content in cells.
    -0005 %
    -0006 % Input:
    -0007 %   model        an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0008 %   protData     structure with proteome data, from loadProtData (Optional,
    -0009 %                by default it instead attempts to load data/paxDB.tsv)
    -0010 %   enzymes      list of enzymes (Optional, default model.ec.enzymes)
    -0011 %   modelAdapter a loaded model adapter (Optional, will otherwise use the
    -0012 %                default model adapter).
    -0013 %
    -0014 % Output:
    -0015 %   f            f-factor
    -0016 %
    -0017 % Usage:
    -0018 %   f = calculateFfactor(model, protData, enzymes, modelAdapter)
    -0019 
    -0020 if nargin < 4 || isempty(modelAdapter)
    -0021     modelAdapter = ModelAdapterManager.getDefault();
    -0022     if isempty(modelAdapter)
    -0023         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0024     end
    -0025 end
    -0026 params = modelAdapter.getParameters();
    -0027 
    -0028 if nargin < 3 || isempty(enzymes)
    -0029     enzymes = model.ec.enzymes;
    -0030 end
    -0031 
    -0032 % Gather proteome data in protData structure
    -0033 if nargin < 2 || isempty(protData)
    -0034     if exist(fullfile(params.path,'data','paxDB.tsv'),'file')
    -0035         protData = fullfile(params.path,'data','paxDB.tsv');
    -0036     else
    -0037         printOrange('WARNING: No proteomics data is provided or can be found. Default f value of 0.5 is returned.\n');
    -0038         f = 0.5;
    -0039     end
    -0040 end
    -0041 
    -0042 % Gather Uniprot database for finding MW
    -0043 uniprotDB = loadDatabases('uniprot', modelAdapter);
    -0044 uniprotDB = uniprotDB.uniprot;
    -0045 
    -0046 if ischar(protData) && endsWith(protData,'paxDB.tsv')
    -0047     fID         = fopen(fullfile(protData),'r');
    -0048     fileContent = textscan(fID,'%s','delimiter','\n');
    -0049     headerLines = find(startsWith(fileContent{1},'#'),1,'last');
    -0050     fclose(fID);
    -0051 
    -0052     %Read data file, excluding headerlines
    -0053     fID         = fopen(fullfile(protData),'r');
    -0054     fileContent = textscan(fID,'%s %s %f','delimiter','\t','HeaderLines',headerLines);
    -0055     genes       = fileContent{2};
    -0056     %Remove internal geneIDs modifiers
    -0057     genes       = regexprep(genes,'^\d+\.','');
    -0058     level       = fileContent{3};
    -0059     fclose(fID);
    -0060     [a,b]       = ismember(genes,uniprotDB.genes);
    -0061     uniprot     = uniprotDB.ID(b(a));
    -0062     level(~a)   = [];
    -0063     clear protData
    -0064     protData.uniprotIDs = uniprot;
    -0065     protData.level   = level;
    -0066     % Get MW and abundance (unit does not matter, f is fraction)
    -0067     [~,idx] = ismember(protData.uniprotIDs,uniprotDB.ID);
    -0068     protData.MW = uniprotDB.MW(idx);
    -0069     protData.abundances = protData.level .* protData.MW;
    -0070 end
    -0071 
    -0072 avgAbundances = mean(protData.abundances,2);
    -0073 totalProt = sum(avgAbundances,'omitnan');
    -0074 
    -0075 % Get enzymes in model
    -0076 enzymesInModel = ismember(protData.uniprotIDs,enzymes);
    -0077 totalEnz = sum(avgAbundances(enzymesInModel),'omitnan');
    -0078 
    -0079 f = totalEnz/totalProt;
    -0080 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/limit_proteins/constrainEnzConcs.html b/doc/src/geckomat/limit_proteins/constrainEnzConcs.html deleted file mode 100644 index cbf7db32..00000000 --- a/doc/src/geckomat/limit_proteins/constrainEnzConcs.html +++ /dev/null @@ -1,128 +0,0 @@ - - - - Description of constrainEnzConcs - - - - - - - - - -
    Home > src > geckomat > limit_proteins > constrainEnzConcs.m
    - - - -

    constrainEnzConcs -

    - -

    PURPOSE ^

    -
    constrainEnzConcs
    - -

    SYNOPSIS ^

    -
    function model = constrainEnzConcs(model, removeConstraints)
    - -

    DESCRIPTION ^

    -
     constrainEnzConcs
    -   Constrain enzyme usages by their concentration as provided in
    -   model.ec.concs. For enzymes with non-NaN entries in model.ec.concs,
    -   their enzyme usage reaction will no longer draw from the protein pool,
    -   but is rather constraint by the measured protein abundance.
    -
    - Input:
    -   model               an ecModel in GECKO 3 format (with ecModel.ec
    -                       structure) with enzyme concentrations in
    -                       model.ec.concs
    -   removeConstraints   logical, whether enzyme concentration
    -                       constraints should be removed (model.ec.concs
    -                       will remain unchanged). (optional, default false)
    -
    - Output:
    -   model   an ecModel constraint with available enzyme concentrations
    -
    - Note: To populate model.ec.concs you should run fillEnzConcs.
    -
    - Usage:
    -   model = constrainEnzConcs(model, removeConstraints)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function model = constrainEnzConcs(model, removeConstraints)
    -0002 % constrainEnzConcs
    -0003 %   Constrain enzyme usages by their concentration as provided in
    -0004 %   model.ec.concs. For enzymes with non-NaN entries in model.ec.concs,
    -0005 %   their enzyme usage reaction will no longer draw from the protein pool,
    -0006 %   but is rather constraint by the measured protein abundance.
    -0007 %
    -0008 % Input:
    -0009 %   model               an ecModel in GECKO 3 format (with ecModel.ec
    -0010 %                       structure) with enzyme concentrations in
    -0011 %                       model.ec.concs
    -0012 %   removeConstraints   logical, whether enzyme concentration
    -0013 %                       constraints should be removed (model.ec.concs
    -0014 %                       will remain unchanged). (optional, default false)
    -0015 %
    -0016 % Output:
    -0017 %   model   an ecModel constraint with available enzyme concentrations
    -0018 %
    -0019 % Note: To populate model.ec.concs you should run fillEnzConcs.
    -0020 %
    -0021 % Usage:
    -0022 %   model = constrainEnzConcs(model, removeConstraints)
    -0023 
    -0024 %Enzyme with NaN entry in model.ec.concs => draw from prot_pool
    -0025 %Enzyme with numeric entry in model.ec.concs => exchange reaction with
    -0026 %enzyme level as UB
    -0027 
    -0028 if nargin<2
    -0029     removeConstraints = false;
    -0030 end
    -0031 
    -0032 %Get indices of usage reactions
    -0033 usageRxns = strcat('usage_prot_',model.ec.enzymes);
    -0034 [~, usageRxnsIdx] = ismember(usageRxns, model.rxns);
    -0035 
    -0036 if any(usageRxnsIdx == 0)
    -0037     error('Usage reactions are not defined for all enzymes. This is done by makeEcModel.')
    -0038 end
    -0039 %Get index of protein pool metabolite
    -0040 protPoolIdx = find(ismember(model.mets,'prot_pool'));
    -0041 if ~any(protPoolIdx)
    -0042     error('Cannot find protein pool pseudometabolite.')
    -0043 end
    -0044 
    -0045 %Protein that should be constraint by UB
    -0046 if removeConstraints
    -0047     protCons = [];
    -0048 else
    -0049     protCons = ~isnan(model.ec.concs);
    -0050 end
    -0051 
    -0052 %Set all reactions to draw from prot_pool
    -0053 model.S(protPoolIdx, usageRxnsIdx) = 1;
    -0054 model.lb(usageRxnsIdx) = -1000;
    -0055 
    -0056 %If non-NaN in model.ec.concs, then constrain by UB
    -0057 if any(protCons)
    -0058 %    model.S(protPoolIdx, usageRxnsIdx(protCons)) = 0; % Since GECKO 3.2.0
    -0059     model.lb(usageRxnsIdx(protCons)) = -model.ec.concs(protCons);
    -0060 end
    -0061 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/limit_proteins/constrainFluxData.html b/doc/src/geckomat/limit_proteins/constrainFluxData.html deleted file mode 100644 index b086da06..00000000 --- a/doc/src/geckomat/limit_proteins/constrainFluxData.html +++ /dev/null @@ -1,217 +0,0 @@ - - - - Description of constrainFluxData - - - - - - - - - -
    Home > src > geckomat > limit_proteins > constrainFluxData.m
    - - - -

    constrainFluxData -

    - -

    PURPOSE ^

    -
    constrainFluxData
    - -

    SYNOPSIS ^

    -
    function model = constrainFluxData(model, fluxData, condition, maxMinGrowth, looseStrictFlux, modelAdapter)
    - -

    DESCRIPTION ^

    -
     constrainFluxData
    -   Constrains fluxes to the data that is provided in the fluxData
    -   structure, which itself is read by loadFluxData from data/fluxData.tsv.
    -
    - Input:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   fluxData        structure with flux data
    -                   conds       sampling condition
    -                   Ptot        total protein (g/gDCW)
    -                   grRate      growth rate (1/h)
    -                   exchFluxes  exchange fluxes (mmol/gDCWh)
    -                   exchMets    exchanged metabolites, matching exchFluxes
    -                   exchRxnIDs  exchange reaction IDs, matching exchMets
    -   condition       either index number or name of the sample condition in
    -                   fluxData.conds (Optional, default = 1)
    -   maxMinGrowth    'max' if the provided growth rate should be set as
    -                   maximum growth rate (= upper bound), or 'min' if it
    -                   should be set as minimum growth rate (= lower bound).
    -                   The latter option is suitable if minimization of
    -                   prot_pool_exchange is used as objective function. (Opt,
    -                   default = 'max')
    -   looseStrictFlux how strictly constrained the exchange fluxes should be,
    -                   optional, default = 'loose'
    -                   'loose' if the exchange fluxes should be constraint
    -                           only by the "outer bounds". If exchFluxes(i)
    -                           > 0, LB = 0 and UB = exchFluxes(i). If
    -                           exchFluxes(i) < 0, LB = exchFluxes(i) and
    -                           UB = 0
    -                   0-100   LB and UB constraints are set with a specified
    -                           percentage of variance around exchFluxes. If 10
    -                           is specified, LB = exchFluxes*0.95 and UB =
    -                           exchFluxes*1.05. This allows for 10% variance
    -                           around the exchFluxes values, but strictly
    -                           forces a flux through the exchRxns.
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use
    -                   the default model adapter)
    -
    - Output:
    -   model           an ecModel where fluxes are constraint
    -
    - Note: If a provided constraint is either -1000 or 1000, then the function
    - will update the reaction lower and upper bound to either allow uptake or
    - excretion, irrespective of what option is given as the looseStrictFlux
    - parameter.
    -
    - Usage:
    -   model = constrainFluxData(model, fluxData, condition, maxMinGrowth, looseStrictFlux, modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function model = constrainFluxData(model, fluxData, condition, maxMinGrowth, looseStrictFlux, modelAdapter)
    -0002 % constrainFluxData
    -0003 %   Constrains fluxes to the data that is provided in the fluxData
    -0004 %   structure, which itself is read by loadFluxData from data/fluxData.tsv.
    -0005 %
    -0006 % Input:
    -0007 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0008 %   fluxData        structure with flux data
    -0009 %                   conds       sampling condition
    -0010 %                   Ptot        total protein (g/gDCW)
    -0011 %                   grRate      growth rate (1/h)
    -0012 %                   exchFluxes  exchange fluxes (mmol/gDCWh)
    -0013 %                   exchMets    exchanged metabolites, matching exchFluxes
    -0014 %                   exchRxnIDs  exchange reaction IDs, matching exchMets
    -0015 %   condition       either index number or name of the sample condition in
    -0016 %                   fluxData.conds (Optional, default = 1)
    -0017 %   maxMinGrowth    'max' if the provided growth rate should be set as
    -0018 %                   maximum growth rate (= upper bound), or 'min' if it
    -0019 %                   should be set as minimum growth rate (= lower bound).
    -0020 %                   The latter option is suitable if minimization of
    -0021 %                   prot_pool_exchange is used as objective function. (Opt,
    -0022 %                   default = 'max')
    -0023 %   looseStrictFlux how strictly constrained the exchange fluxes should be,
    -0024 %                   optional, default = 'loose'
    -0025 %                   'loose' if the exchange fluxes should be constraint
    -0026 %                           only by the "outer bounds". If exchFluxes(i)
    -0027 %                           > 0, LB = 0 and UB = exchFluxes(i). If
    -0028 %                           exchFluxes(i) < 0, LB = exchFluxes(i) and
    -0029 %                           UB = 0
    -0030 %                   0-100   LB and UB constraints are set with a specified
    -0031 %                           percentage of variance around exchFluxes. If 10
    -0032 %                           is specified, LB = exchFluxes*0.95 and UB =
    -0033 %                           exchFluxes*1.05. This allows for 10% variance
    -0034 %                           around the exchFluxes values, but strictly
    -0035 %                           forces a flux through the exchRxns.
    -0036 %   modelAdapter    a loaded model adapter (Optional, will otherwise use
    -0037 %                   the default model adapter)
    -0038 %
    -0039 % Output:
    -0040 %   model           an ecModel where fluxes are constraint
    -0041 %
    -0042 % Note: If a provided constraint is either -1000 or 1000, then the function
    -0043 % will update the reaction lower and upper bound to either allow uptake or
    -0044 % excretion, irrespective of what option is given as the looseStrictFlux
    -0045 % parameter.
    -0046 %
    -0047 % Usage:
    -0048 %   model = constrainFluxData(model, fluxData, condition, maxMinGrowth, looseStrictFlux, modelAdapter)
    -0049 
    -0050 if nargin < 6 || isempty(modelAdapter)
    -0051     modelAdapter = ModelAdapterManager.getDefault();
    -0052     if isempty(modelAdapter)
    -0053         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0054     end
    -0055 end
    -0056 params = modelAdapter.getParameters();
    -0057 
    -0058 if nargin < 5 || isempty(looseStrictFlux)
    -0059     looseStrictFlux = 'loose';
    -0060 end
    -0061 
    -0062 if nargin < 4 || isempty(maxMinGrowth)
    -0063     maxMinGrowth = 'max';
    -0064 end
    -0065 
    -0066 if nargin < 2 || isempty(fluxData)
    -0067     fluxData = loadFluxData(fullfile(params.path,'data','fluxData.tsv'),modelAdapter);
    -0068 end
    -0069 
    -0070 if nargin < 3 || isempty(condition)
    -0071     condition = 1;
    -0072 elseif ~isnumeric(condition)
    -0073     idx = find(strcmp(fluxData.conds,condition));
    -0074     if isempty(condition)
    -0075         error(['Condition ' condition ' cannot be found in fluxData'])
    -0076     else
    -0077         condition = idx;
    -0078     end
    -0079 end
    -0080 
    -0081 % Select the exchange fluxes of specified condition
    -0082 fluxData.exchFluxes = fluxData.exchFluxes(condition,:);
    -0083 
    -0084 %Set original c-source to zero
    -0085 model = setParam(model,'eq',params.c_source,0);
    -0086 %Set growth
    -0087 switch maxMinGrowth
    -0088     case 'max'
    -0089         model = setParam(model,'lb',params.bioRxn,0);
    -0090         model = setParam(model,'ub',params.bioRxn,fluxData.grRate(condition));
    -0091     case 'min'
    -0092         model = setParam(model,'lb',params.bioRxn,fluxData.grRate(condition));
    -0093         model = setParam(model,'ub',params.bioRxn,1000);
    -0094 end
    -0095 
    -0096 naFlux = isnan(fluxData.exchFluxes);
    -0097 negFlux = lt(fluxData.exchFluxes,0); % less than 0
    -0098 ub = fluxData.exchFluxes(~(negFlux | naFlux));
    -0099 posFlux = fluxData.exchRxnIDs(~(negFlux | naFlux));
    -0100 lb = fluxData.exchFluxes(negFlux & ~naFlux);
    -0101 negFlux = fluxData.exchRxnIDs(negFlux & ~naFlux);
    -0102 
    -0103 switch looseStrictFlux
    -0104     case 'loose'
    -0105         model = setParam(model,'lb',negFlux,lb);
    -0106         model = setParam(model,'ub',negFlux,0);
    -0107         model = setParam(model,'lb',posFlux,0);
    -0108         model = setParam(model,'ub',posFlux,ub);
    -0109     otherwise
    -0110         model = setParam(model,'var',fluxData.exchRxnIDs,fluxData.exchFluxes,looseStrictFlux);
    -0111 end
    -0112 extremeFlux = find(abs(fluxData.exchFluxes)==1000);
    -0113 if any(extremeFlux)
    -0114     exchFlux = fluxData.exchFluxes(extremeFlux);
    -0115     if any(exchFlux==-1000)
    -0116         model = setParam(model,'lb',fluxData.exchRxnIDs(extremeFlux(exchFlux==-1000)),-1000);
    -0117         model = setParam(model,'ub',fluxData.exchRxnIDs(extremeFlux(exchFlux==-1000)),0);
    -0118     end
    -0119     if any(exchFlux==1000)
    -0120         model = setParam(model,'lb',fluxData.exchRxnIDs(extremeFlux(exchFlux==1000)),0);
    -0121         model = setParam(model,'ub',fluxData.exchRxnIDs(extremeFlux(exchFlux==1000)),1000);
    -0122     end
    -0123 end
    -0124 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/limit_proteins/fillEnzConcs.html b/doc/src/geckomat/limit_proteins/fillEnzConcs.html deleted file mode 100644 index f78b07f3..00000000 --- a/doc/src/geckomat/limit_proteins/fillEnzConcs.html +++ /dev/null @@ -1,115 +0,0 @@ - - - - Description of fillEnzConcs - - - - - - - - - -
    Home > src > geckomat > limit_proteins > fillEnzConcs.m
    - - - -

    fillEnzConcs -

    - -

    PURPOSE ^

    -
    fillEnzConcs
    - -

    SYNOPSIS ^

    -
    function model = fillEnzConcs(model, protData, dataCol)
    - -

    DESCRIPTION ^

    -
     fillEnzConcs
    -   Uses the protein concentrations from protData to fill model.ec.concs.
    -   Protein levels should be provided in mg/gDCW. If no data is provided
    -   a particular protein, its level is NaN. Existing entries in
    -   model.ec.concs are overwritten.
    -
    - Input:
    -   model       an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   protData    structure with proteome data, from loadProtFluxData
    -               uniprotIDs      cell arrray with Uniprot IDs matching
    -                               protData.abundances
    -               abundances      matrix of proteomics data
    -   dataCol     number indicating the column in protData.abundances that
    -               contains the relevant protein concentrations (protData may
    -               contain data from multiple conditions/samples/experiments,
    -               each with their own column in protData.abundances.
    -               Optional, default = 1.
    -
    - Output:
    -   model       an ecModel where model.ec.concs is populated with protein
    -               concentrations.
    -
    - Note: to also constrain the model with the content of model.ec.concs, you
    - should run constrainEnzConcs.
    -
    - Usage:
    -   model = fillEnzConcs(model, protData)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function model = fillEnzConcs(model, protData, dataCol)
    -0002 % fillEnzConcs
    -0003 %   Uses the protein concentrations from protData to fill model.ec.concs.
    -0004 %   Protein levels should be provided in mg/gDCW. If no data is provided
    -0005 %   a particular protein, its level is NaN. Existing entries in
    -0006 %   model.ec.concs are overwritten.
    -0007 %
    -0008 % Input:
    -0009 %   model       an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0010 %   protData    structure with proteome data, from loadProtFluxData
    -0011 %               uniprotIDs      cell arrray with Uniprot IDs matching
    -0012 %                               protData.abundances
    -0013 %               abundances      matrix of proteomics data
    -0014 %   dataCol     number indicating the column in protData.abundances that
    -0015 %               contains the relevant protein concentrations (protData may
    -0016 %               contain data from multiple conditions/samples/experiments,
    -0017 %               each with their own column in protData.abundances.
    -0018 %               Optional, default = 1.
    -0019 %
    -0020 % Output:
    -0021 %   model       an ecModel where model.ec.concs is populated with protein
    -0022 %               concentrations.
    -0023 %
    -0024 % Note: to also constrain the model with the content of model.ec.concs, you
    -0025 % should run constrainEnzConcs.
    -0026 %
    -0027 % Usage:
    -0028 %   model = fillEnzConcs(model, protData)
    -0029 
    -0030 if nargin < 3 || isempty(dataCol)
    -0031     dataCol = 1;
    -0032 end
    -0033 
    -0034 uniprotIDs = protData.uniprotIDs;
    -0035 abundances = protData.abundances(:,dataCol);
    -0036 
    -0037 %Redefine an empty model.ec.concs vector
    -0038 model.ec.concs=nan(numel(model.ec.enzymes),1);
    -0039 
    -0040 [a,b] = ismember(uniprotIDs, model.ec.enzymes);
    -0041 model.ec.concs(b(a)) = abundances(a);
    -0042 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/limit_proteins/flexibilizeEnzConcs.html b/doc/src/geckomat/limit_proteins/flexibilizeEnzConcs.html deleted file mode 100644 index f63a0379..00000000 --- a/doc/src/geckomat/limit_proteins/flexibilizeEnzConcs.html +++ /dev/null @@ -1,335 +0,0 @@ - - - - Description of flexibilizeEnzConcs - - - - - - - - - -
    Home > src > geckomat > limit_proteins > flexibilizeEnzConcs.m
    - - - -

    flexibilizeEnzConcs -

    - -

    PURPOSE ^

    -
    flexibilizeEnzConcs
    - -

    SYNOPSIS ^

    -
    function [model, flexEnz] = flexibilizeEnzConcs(model, expGrowth, foldChange, iterPerEnzyme, modelAdapter, verbose)
    - -

    DESCRIPTION ^

    -
     flexibilizeEnzConcs
    -   Flexibilize enzyme concentration of an ecModel with constrained with
    -   proteomics data. The upper bound of the protein usage reaction is
    -   changed, while the concentrations in ecModel.ec.concs remain unchanged.
    -
    -   If no (more) limiting enzyme concentrations can be found, it might be
    -   the protein pool exchange that is limiting growth. In that case, an
    -   attempt will be made to relax the protein pool exchange reaction, and
    -   if the growth rate indeed increases, it is suggested to set the protein
    -   pool exchange unconstrained (lb=-1000) before again running
    -   flexibilizeEnzConcs. Such situations, where a proteomics integrated
    -   ecModel is overconstrained, may occur if the ecModel should be able to
    -   simulate maximum growth rate (from e.g. batch cultivation). 
    -   
    -   If relaxing the protein pool exchange does not increase the growth
    -   rate, then this is not due to enzyme constraints, but rather an issue
    -   with the metabolic network itself, or the set nutrient exchange is not
    -   sufficient.
    -
    - Input:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   expGrowth       estimated experimental growth rate. If not specified,
    -                   the value will be read from the model adapter
    -   foldChange      a value how much increase the enzyme concentration
    -                   (Optional, default = 2)
    -   iterPerEnzyme   the number of iterations that an enzyme can be increased.
    -                   A zero number can be defined. if zero is defined no limit
    -                   will be set, and it will increase the enzyme concentration
    -                   until reach de defined growth rate (Optional, default = 5)
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -                   default model adapter)
    -   verbose         logical whether progress should be reported (Optional,
    -                   default true)
    -
    - Output:
    -   model           ecModel where the constraint of measured enzyme
    -                   concentrations have been flexibilized (=relaxed) in the
    -                   S-matrix, to allow the model to reach the growth rate
    -                   defined in expGrowth, while the values in
    -                   ecModel.ec.concs have remained untouched.
    -   flexEnz         array with information about flexibilized proteins
    -                   uniprotIDs  enzymes whose usage UB was flexibilized
    -                   oldConcs    original concentrations, from mode.ec.concs
    -                   flexConcs   flexibilized concentrations, new UB in
    -                               model
    -                   ratioIncr   ratio by which the concentration increased,
    -                               the enzymes will be sorted by this field
    -                   frequence   numeric how often the enzyme has been
    -                               step-wise flexibilized
    -
    - Usage:
    -   [model, flexEnz] = flexibilizeEnzConcs(model, expGrowth, foldChange, iterPerEnzyme, modelAdapter, verbose)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: - -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function [model, flexEnz] = flexibilizeEnzConcs(model, expGrowth, foldChange, iterPerEnzyme, modelAdapter, verbose)
    -0002 % flexibilizeEnzConcs
    -0003 %   Flexibilize enzyme concentration of an ecModel with constrained with
    -0004 %   proteomics data. The upper bound of the protein usage reaction is
    -0005 %   changed, while the concentrations in ecModel.ec.concs remain unchanged.
    -0006 %
    -0007 %   If no (more) limiting enzyme concentrations can be found, it might be
    -0008 %   the protein pool exchange that is limiting growth. In that case, an
    -0009 %   attempt will be made to relax the protein pool exchange reaction, and
    -0010 %   if the growth rate indeed increases, it is suggested to set the protein
    -0011 %   pool exchange unconstrained (lb=-1000) before again running
    -0012 %   flexibilizeEnzConcs. Such situations, where a proteomics integrated
    -0013 %   ecModel is overconstrained, may occur if the ecModel should be able to
    -0014 %   simulate maximum growth rate (from e.g. batch cultivation).
    -0015 %
    -0016 %   If relaxing the protein pool exchange does not increase the growth
    -0017 %   rate, then this is not due to enzyme constraints, but rather an issue
    -0018 %   with the metabolic network itself, or the set nutrient exchange is not
    -0019 %   sufficient.
    -0020 %
    -0021 % Input:
    -0022 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0023 %   expGrowth       estimated experimental growth rate. If not specified,
    -0024 %                   the value will be read from the model adapter
    -0025 %   foldChange      a value how much increase the enzyme concentration
    -0026 %                   (Optional, default = 2)
    -0027 %   iterPerEnzyme   the number of iterations that an enzyme can be increased.
    -0028 %                   A zero number can be defined. if zero is defined no limit
    -0029 %                   will be set, and it will increase the enzyme concentration
    -0030 %                   until reach de defined growth rate (Optional, default = 5)
    -0031 %   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -0032 %                   default model adapter)
    -0033 %   verbose         logical whether progress should be reported (Optional,
    -0034 %                   default true)
    -0035 %
    -0036 % Output:
    -0037 %   model           ecModel where the constraint of measured enzyme
    -0038 %                   concentrations have been flexibilized (=relaxed) in the
    -0039 %                   S-matrix, to allow the model to reach the growth rate
    -0040 %                   defined in expGrowth, while the values in
    -0041 %                   ecModel.ec.concs have remained untouched.
    -0042 %   flexEnz         array with information about flexibilized proteins
    -0043 %                   uniprotIDs  enzymes whose usage UB was flexibilized
    -0044 %                   oldConcs    original concentrations, from mode.ec.concs
    -0045 %                   flexConcs   flexibilized concentrations, new UB in
    -0046 %                               model
    -0047 %                   ratioIncr   ratio by which the concentration increased,
    -0048 %                               the enzymes will be sorted by this field
    -0049 %                   frequence   numeric how often the enzyme has been
    -0050 %                               step-wise flexibilized
    -0051 %
    -0052 % Usage:
    -0053 %   [model, flexEnz] = flexibilizeEnzConcs(model, expGrowth, foldChange, iterPerEnzyme, modelAdapter, verbose)
    -0054 
    -0055 if nargin < 6 || isempty(verbose)
    -0056     verbose = true;
    -0057 end
    -0058 if nargin < 5 || isempty(modelAdapter)
    -0059     modelAdapter = ModelAdapterManager.getDefault();
    -0060     if isempty(modelAdapter)
    -0061         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0062     end
    -0063 end
    -0064 params = modelAdapter.getParameters();
    -0065 
    -0066 if nargin < 4 || isempty(iterPerEnzyme)
    -0067     iterPerEnzyme = 5;
    -0068 end
    -0069 
    -0070 if nargin < 3 || isempty(foldChange)
    -0071     foldChange = 2;
    -0072 end
    -0073 
    -0074 if nargin < 2 || isempty(expGrowth)
    -0075     expGrowth = modelAdapter.getParameters().gR_exp;
    -0076 end
    -0077 
    -0078 % If a zero value is defined, not iteration limit will be set
    -0079 if iterPerEnzyme == 0
    -0080     iterPerEnzyme = inf;
    -0081 end
    -0082 
    -0083 bioRxnIdx = getIndexes(model,params.bioRxn,'rxns');
    -0084 if model.ub(bioRxnIdx) < expGrowth
    -0085     fprintf(['The upper bound of the biomass reaction was %s, while expGrowth '...
    -0086              'is %s. The upper bound has been set to expGrowth.'],...
    -0087              num2str(model.ub(bioRxnIdx)), num2str(expGrowth))
    -0088     model.ub(bioRxnIdx) = expGrowth;
    -0089 end
    -0090 
    -0091 % Keep track if protein pool will be flexibilized
    -0092 changedProtPool = false;
    -0093 
    -0094 % In case the model have not been protein constrained
    -0095 % model = constrainEnzConcs(model);
    -0096 
    -0097 [sol,hs] = solveLP(model);
    -0098 predGrowth = sol.f;
    -0099 
    -0100 % Get those proteins with a concentration defined
    -0101 protConcs = find(~isnan(model.ec.concs));
    -0102 
    -0103 % Get enzymes names with a concentration value
    -0104 proteins = model.ec.enzymes(protConcs);
    -0105 
    -0106 % Store how many time is predicted a enzyme with the highest coeff
    -0107 frequence = zeros(numel(proteins),1);
    -0108 
    -0109 flexBreak=false;
    -0110 if any(protConcs)
    -0111     while predGrowth < expGrowth
    -0112 
    -0113         % Get the control coefficients
    -0114         [~, controlCoeffs] = getConcControlCoeffs(model, proteins, foldChange, 0.75);
    -0115 
    -0116         % Stop looking for limiting proteins all coeffs are zero
    -0117         if any(controlCoeffs)
    -0118 
    -0119             % Find the maximum coefficient index
    -0120             [~,maxIdx] = max(controlCoeffs);
    -0121 
    -0122             % Increase +1 the frequence
    -0123             frequence(maxIdx) = frequence(maxIdx) + 1;
    -0124 
    -0125             % Allow to increase the UB maximum five times
    -0126             if frequence(maxIdx) <= iterPerEnzyme
    -0127 
    -0128                 % Set how much will increase the UB
    -0129                 increase = foldChange*frequence(maxIdx);
    -0130 
    -0131                 % Get usage rxn for the highest coeff
    -0132                 protUsageIdx = strcmpi(model.rxns, strcat('usage_prot_', proteins(maxIdx)));
    -0133 
    -0134                 % replace the UB
    -0135                 model.lb(protUsageIdx) = -(model.ec.concs(protConcs(maxIdx)) * (1+increase));
    -0136 
    -0137                 % Get the new growth rate
    -0138                 sol = solveLP(model,0,[],hs);
    -0139                 predGrowth = sol.f;
    -0140 
    -0141                 if verbose
    -0142                     disp(['Protein ' proteins{maxIdx} ' LB adjusted. Grow: ' num2str(predGrowth)])
    -0143                 end
    -0144             else
    -0145                 printOrange(['WARNING: Limit has been reached. Protein '  proteins{maxIdx} ' seems to be problematic. Consider changing the kcat.\n']);
    -0146                 flexBreak=true;
    -0147                 break
    -0148             end
    -0149         else
    -0150             disp('No (more) limiting enzymes have been found. Attempting to increase protein pool exchange...')
    -0151             protPoolIdx = getIndexes(model,'prot_pool_exchange','rxns');
    -0152             oldProtPool = -model.lb(protPoolIdx);
    -0153             tempModel = setParam(model,'lb',protPoolIdx,-1000);
    -0154             tempModel = setParam(tempModel,'ub',bioRxnIdx,expGrowth);
    -0155             sol = solveLP(tempModel);
    -0156             if (sol.f-predGrowth)>1e-10 % There is improvement in growth rate
    -0157                 % Find new protein pool constraint
    -0158                 predGrowth = sol.f;
    -0159                 tempModel = setParam(tempModel,'lb',bioRxnIdx,predGrowth);
    -0160                 tempModel = setParam(tempModel,'obj',protPoolIdx,1);
    -0161                 sol = solveLP(tempModel);
    -0162                 newProtPool = sol.f;
    -0163                 model.lb(protPoolIdx) = -newProtPool;
    -0164                 fprintf(['Changing the lower bound of protein pool exchange from %s ',...
    -0165                          'to %s enabled a\ngrowth rate of %s. It can be helpful to set ', ...
    -0166                          'the lower bound of protein\npool exchange to -1000 before ',...
    -0167                          'running flexibilizeEnzConcs.\n'],num2str(-oldProtPool), ...
    -0168                          num2str(-newProtPool),num2str(predGrowth));
    -0169                 changedProtPool = true;
    -0170             else
    -0171                 fprintf(['Protein pool exchange was also not limiting. Inability to reach growth ',...
    -0172                         'rate is not related to\nenzyme constraints. Maximum growth rate ',...
    -0173                         'is %s.\n'], num2str(predGrowth))
    -0174             end
    -0175             % To return an usable model with these conditions, set the
    -0176             % highest growth rate reached as the experimental value
    -0177             expGrowth = predGrowth;
    -0178             break
    -0179         end
    -0180     end
    -0181 else
    -0182     error('Protein concentrations have not been defined. Please run readProteomics and constrainEnzConcs')
    -0183 end
    -0184 
    -0185 protFlex         = proteins(frequence>0);
    -0186 [~,protUsageIdx] = ismember(strcat('usage_prot_', protFlex), model.rxns);
    -0187 [~,ecProtId]     = ismember(protFlex, model.ec.enzymes);
    -0188 oldConcs         = model.ec.concs(ecProtId);
    -0189 %frequence        = frequence(ecProtId);
    -0190 
    -0191 if flexBreak == false && ~isempty(protFlex)
    -0192     % Not all flexibilized proteins require flexibilization in the end
    -0193     % Test flux distribution with minimum prot_pool usage
    -0194     modelTemp       = setParam(model,'var',params.bioRxn,expGrowth,0.5);
    -0195     modelTemp       = setParam(modelTemp,'obj','prot_pool_exchange',1);
    -0196     sol             = solveLP(modelTemp,1);
    -0197     % Check which concentrations can remain unchanged
    -0198     newConcs        = abs(sol.x(protUsageIdx));
    -0199     keepOld         = newConcs<oldConcs;
    -0200     % Set UBs
    -0201     model.lb(protUsageIdx(keepOld))  = -oldConcs(keepOld);
    -0202     model.lb(protUsageIdx(~keepOld)) = -newConcs(~keepOld);
    -0203     % Output structure
    -0204     protFlex(keepOld) = [];
    -0205     oldConcs(keepOld) = [];
    -0206     newConcs(keepOld) = [];
    -0207     frequence=frequence(frequence>0);
    -0208     frequence(keepOld) = [];
    -0209     
    -0210     flexEnz.uniprotIDs = protFlex;
    -0211     flexEnz.oldConcs   = oldConcs;
    -0212     flexEnz.flexConcs  = newConcs;
    -0213     flexEnz.frequence  = frequence(frequence>0);
    -0214 else
    -0215     protFlex           = proteins(frequence>0);
    -0216     [~, protUsageIdx]  = ismember(strcat('usage_prot_', protFlex), model.rxns);
    -0217 
    -0218     flexEnz.uniprotIDs = protFlex;
    -0219     flexEnz.oldConcs   = model.ec.concs(ecProtId);
    -0220     flexEnz.flexConcs  = abs(model.lb(protUsageIdx));
    -0221     flexEnz.frequence  = frequence(frequence>0);
    -0222 end
    -0223 if changedProtPool
    -0224     flexEnz.uniprotIDs(end+1) = {'prot_pool'};
    -0225     flexEnz.oldConcs(end+1)   = oldProtPool;
    -0226     flexEnz.flexConcs(end+1)  = newProtPool;
    -0227     flexEnz.frequence(end+1)  = 1;
    -0228 end
    -0229 % Sort by biggest ratio increase
    -0230 flexEnz.ratioIncr  = flexEnz.flexConcs./flexEnz.oldConcs;
    -0231 [~,b] = sort(flexEnz.ratioIncr,'descend');
    -0232 flexEnz.ratioIncr  = flexEnz.ratioIncr(b);
    -0233 flexEnz.uniprotIDs = flexEnz.uniprotIDs(b);
    -0234 flexEnz.oldConcs   = flexEnz.oldConcs(b);
    -0235 flexEnz.flexConcs  = flexEnz.flexConcs(b);
    -0236 flexEnz.frequence  = flexEnz.frequence(b);
    -0237 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/limit_proteins/getConcControlCoeffs.html b/doc/src/geckomat/limit_proteins/getConcControlCoeffs.html deleted file mode 100644 index 85739751..00000000 --- a/doc/src/geckomat/limit_proteins/getConcControlCoeffs.html +++ /dev/null @@ -1,141 +0,0 @@ - - - - Description of getConcControlCoeffs - - - - - - - - - -
    Home > src > geckomat > limit_proteins > getConcControlCoeffs.m
    - - - -

    getConcControlCoeffs -

    - -

    PURPOSE ^

    -
    getConcControlCoeffs
    - -

    SYNOPSIS ^

    -
    function [enz, controlCoeffs] = getConcControlCoeffs(model, proteins, foldChange, limit)
    - -

    DESCRIPTION ^

    -
     getConcControlCoeffs
    -   Calculate an control coefficients of protein usage.
    -
    - Input:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   proteins        a list of proteins to calculate the coefficients. (Optional,
    -                   default = model.ec.enzymes)
    -   foldChange      a value how much increase the protein concentration.
    -                   (Optional, default = 2)
    -   limit           a value to determine limiting protein usage reactions.
    -                   Calculate as usage/concentration (Optional, default = 0)
    -
    - Output:
    -   enz             a logical vector of enzymes analyzed
    -   controlCoeffs   a vector array with the coefficients
    -
    - Usage:
    -    [enz, controlCoeffs] = getConcControlCoeffs(model, proteins, foldChange, limit);
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: - - - - - -

    SOURCE CODE ^

    -
    0001 function [enz, controlCoeffs] = getConcControlCoeffs(model, proteins, foldChange, limit)
    -0002 % getConcControlCoeffs
    -0003 %   Calculate an control coefficients of protein usage.
    -0004 %
    -0005 % Input:
    -0006 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0007 %   proteins        a list of proteins to calculate the coefficients. (Optional,
    -0008 %                   default = model.ec.enzymes)
    -0009 %   foldChange      a value how much increase the protein concentration.
    -0010 %                   (Optional, default = 2)
    -0011 %   limit           a value to determine limiting protein usage reactions.
    -0012 %                   Calculate as usage/concentration (Optional, default = 0)
    -0013 %
    -0014 % Output:
    -0015 %   enz             a logical vector of enzymes analyzed
    -0016 %   controlCoeffs   a vector array with the coefficients
    -0017 %
    -0018 % Usage:
    -0019 %    [enz, controlCoeffs] = getConcControlCoeffs(model, proteins, foldChange, limit);
    -0020 
    -0021 if nargin < 4 || isempty(limit)
    -0022     limit = 0;
    -0023 end
    -0024 
    -0025 if nargin < 3 || isempty(foldChange)
    -0026     foldChange = 2;
    -0027 end
    -0028 
    -0029 if nargin < 2 || isempty(proteins)
    -0030     proteins = model.ec.enzymes;
    -0031 end
    -0032 
    -0033 % for now
    -0034 enz = false(length(proteins),1);
    -0035 controlCoeffs = zeros(length(proteins),1);
    -0036 
    -0037 [sol,hs] = solveLP(model);
    -0038 initialGrowth = sol.f;
    -0039 
    -0040 % Get enzyme index
    -0041 [~, protIdx] = ismember(proteins, model.ec.enzymes);
    -0042 
    -0043 % Get the protein usage reactions
    -0044 protUsageRxns = strcat('usage_prot_', model.ec.enzymes(protIdx));
    -0045 [~, protUsageRxnIdx] = ismember(protUsageRxns, model.rxns);
    -0046 
    -0047 for i = 1:numel(proteins)
    -0048     % Get the previous concentration
    -0049     prevConc = model.lb(protUsageRxnIdx(i));
    -0050 
    -0051     % Only consider those with a usage close the UB
    -0052     if (sol.x(protUsageRxnIdx(i))/prevConc) > limit
    -0053         
    -0054         % Update the logical vector
    -0055         enz(i) = 1;
    -0056 
    -0057         % Create a temporal model since coeff will be calculated one enzyme at
    -0058         % the time, without other change
    -0059         tempModel = model;
    -0060         % Increase the concentration by flexfactor
    -0061         newConc = prevConc*(foldChange);
    -0062         tempModel.lb(protUsageRxnIdx(i)) = newConc;
    -0063 
    -0064         % Get the new growth rate after the adjustment
    -0065         [tempSol,hs] = solveLP(tempModel,0,[],hs);
    -0066         tempGrowth = tempSol.f;
    -0067         
    -0068         % Calculate the coeff only if new growth rate is significantly
    -0069         % higher than initial value
    -0070         if (tempGrowth-initialGrowth)>1e-10
    -0071             controlCoeffs(i) = (tempGrowth-initialGrowth)/(prevConc-newConc);
    -0072         end
    -0073     end
    -0074 
    -0075 end
    -0076 end
    -0077
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/limit_proteins/index.html b/doc/src/geckomat/limit_proteins/index.html deleted file mode 100644 index 42f693ff..00000000 --- a/doc/src/geckomat/limit_proteins/index.html +++ /dev/null @@ -1,29 +0,0 @@ - - - - Index for Directory src\geckomat\limit_proteins - - - - - - - - - - -
    < Master indexIndex for src\geckomat\limit_proteins >
    - -

    Index for src\geckomat\limit_proteins

    - -

    Matlab files in this directory:

    - -
     calculateFfactorcalculateFfactor
     constrainEnzConcsconstrainEnzConcs
     constrainFluxDataconstrainFluxData
     fillEnzConcsfillEnzConcs
     flexibilizeEnzConcsflexibilizeEnzConcs
     getConcControlCoeffsgetConcControlCoeffs
     updateProtPoolupdateProtPool
    - - - - -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/limit_proteins/updateProtPool.html b/doc/src/geckomat/limit_proteins/updateProtPool.html deleted file mode 100644 index e757f1f7..00000000 --- a/doc/src/geckomat/limit_proteins/updateProtPool.html +++ /dev/null @@ -1,151 +0,0 @@ - - - - Description of updateProtPool - - - - - - - - - -
    Home > src > geckomat > limit_proteins > updateProtPool.m
    - - - -

    updateProtPool -

    - -

    PURPOSE ^

    -
    updateProtPool
    - -

    SYNOPSIS ^

    -
    function ecModel = updateProtPool(ecModel, Ptot, modelAdapter)
    - -

    DESCRIPTION ^

    -
     updateProtPool
    -   Obsolete since GECKO 3.2.0, as all (measured and unmeasured) enzymes
    -   are drawn from the protein pool. Instead, use setProtPoolSize. See
    -   https://github.com/SysBioChalmers/GECKO/issues/375 for explanation.
    -
    -   Before GECKO 3.2.0: updates the protein pool to compensate for measured
    -   proteomics data (in model.ec.concs), as only the unmeasured enzymes
    -   draw from the protein pool.
    -
    - Input:
    -   ecModel         an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   Ptot            total protein content in g/gDCW, overwrites the value
    -                   from modelAdapter. For instance, condition-specific
    -                   fluxData.Ptot from loadFluxData can be used. If nothing
    -                   is provided, the modelAdapter value is used.
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -                   default model adapter).
    -
    - Output:
    -   model           an ecModel where model.ec.concs is populated with
    -                   protein concentrations
    - Usage:
    -   ecModel  = updateProtPool(ecModel, Ptot, modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function ecModel  = updateProtPool(ecModel, Ptot, modelAdapter)
    -0002 % updateProtPool
    -0003 %   Obsolete since GECKO 3.2.0, as all (measured and unmeasured) enzymes
    -0004 %   are drawn from the protein pool. Instead, use setProtPoolSize. See
    -0005 %   https://github.com/SysBioChalmers/GECKO/issues/375 for explanation.
    -0006 %
    -0007 %   Before GECKO 3.2.0: updates the protein pool to compensate for measured
    -0008 %   proteomics data (in model.ec.concs), as only the unmeasured enzymes
    -0009 %   draw from the protein pool.
    -0010 %
    -0011 % Input:
    -0012 %   ecModel         an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0013 %   Ptot            total protein content in g/gDCW, overwrites the value
    -0014 %                   from modelAdapter. For instance, condition-specific
    -0015 %                   fluxData.Ptot from loadFluxData can be used. If nothing
    -0016 %                   is provided, the modelAdapter value is used.
    -0017 %   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -0018 %                   default model adapter).
    -0019 %
    -0020 % Output:
    -0021 %   model           an ecModel where model.ec.concs is populated with
    -0022 %                   protein concentrations
    -0023 % Usage:
    -0024 %   ecModel  = updateProtPool(ecModel, Ptot, modelAdapter)
    -0025 
    -0026 % Do not run from GECKO version 3.2.0 onwards. This can be recognized by
    -0027 % prot_usage reactions that are constrained by proteomics and still draw
    -0028 % from the protein pool
    -0029 protRxns = find(startsWith(ecModel.rxns,'usage_prot_'));
    -0030 poolMetIdx = find(strcmp(ecModel.mets,'prot_pool'));
    -0031 % Selected proteins with proteomics constraints
    -0032 constProtRxns = ~(ecModel.lb(protRxns)==-1000);
    -0033 % Are any still drawing from prot_pool? This is introduced in GECKO 3.2.0.
    -0034 if any(full(ecModel.S(poolMetIdx,protRxns(constProtRxns))))
    -0035     error(['In the provided ecModel, all protein usage reactions, both with ' ...
    -0036         'and without concentration constraints, draw from the protein pool. ' ...
    -0037         'This was introduced with GECKO 3.2.0. Since then, updateProtPool ' ...
    -0038         'has become obsolete, use setProtPoolSize instead to constrain the ' ...
    -0039         'total protein pool with  condition-specific total protein content. See '...
    -0040         '<a href="https://github.com/SysBioChalmers/GECKO/issues/375">here</a> ' ...
    -0041         'for more explanation.'])
    -0042 end
    -0043 
    -0044 if nargin < 3 || isempty(modelAdapter)
    -0045     modelAdapter = ModelAdapterManager.getDefault();
    -0046     if isempty(modelAdapter)
    -0047         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0048     end
    -0049 end
    -0050 params = modelAdapter.params;
    -0051 
    -0052 if nargin < 2 || isempty(Ptot)
    -0053     Ptot = params.Ptot;
    -0054     disp(['Total protein content used: ' num2str(Ptot) ' [g protein/gDw]'])
    -0055 end
    -0056 
    -0057 % Convert Ptot to mg/gDW if provided in g/gDCW (which is default)
    -0058 if Ptot < 1
    -0059     Ptot = Ptot * 1000;
    -0060 end
    -0061 
    -0062 Pmeas = sum(ecModel.ec.concs,'omitnan');
    -0063 if Pmeas == 0
    -0064     error('The model has not yet been populated with proteomics, as ecModel.ec.concs is empty.')
    -0065 end
    -0066 
    -0067 Pnew = (Ptot - Pmeas) * params.f;
    -0068 
    -0069 if Pnew > 0
    -0070     PoolRxnIdx = strcmp(ecModel.rxns,'prot_pool_exchange');
    -0071     ecModel.lb(PoolRxnIdx) = -Pnew*params.sigma;
    -0072     sol = solveLP(ecModel);
    -0073     if isempty(sol.x)
    -0074         error(['Estimating the remaining protein pool by subtracting the ' ...
    -0075                'sum of measured enzyme concentrations (in ecModel.ec.concs) ' ...
    -0076                'from the total protein pool (Ptot) does not yield a functional ' ...
    -0077                'model.'])
    -0078     end
    -0079 else
    -0080     error('The total measured protein mass exceeds the total protein content.')
    -0081 end
    -0082 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/model_adapter/ModelAdapter.html b/doc/src/geckomat/model_adapter/ModelAdapter.html deleted file mode 100644 index 7d1301b5..00000000 --- a/doc/src/geckomat/model_adapter/ModelAdapter.html +++ /dev/null @@ -1,115 +0,0 @@ - - - - Description of ModelAdapter - - - - - - - - - -
    Home > src > geckomat > model_adapter > ModelAdapter.m
    - - - -

    ModelAdapter -

    - -

    PURPOSE ^

    -
    Abstract Base class for adapters for different species
    - -

    SYNOPSIS ^

    -
    This is a script file.
    - -

    DESCRIPTION ^

    -
    Abstract Base class for adapters for different species
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    • ModelAdapter Abstract Base class for adapters for different species
    -This function is called by: - - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 %Abstract Base class for adapters for different species
    -0002 classdef (Abstract) ModelAdapter
    -0003     methods (Abstract)
    -0004         [spont,spontRxnNames] = getSpontaneousReactions(obj,model);
    -0005     end
    -0006     methods
    -0007         %not really needed, we could access it directly. Not very nice, but practical
    -0008         function parameters = getParameters(obj)
    -0009             parameters = obj.params;
    -0010         end
    -0011 
    -0012         %This allows for changing parameters in an adapter without
    -0013         %creating a new class. May be convenient, although less clean
    -0014         %function obj = setParameters(obj, parameters)
    -0015         %    obj.mParams = parameters;
    -0016         %end
    -0017 
    -0018         %The genes returned here should match the gene id set in the parameter params.uniprot.geneIDfield
    -0019         function genes = getUniprotCompatibleGenes(obj,inGenes)
    -0020             genes = inGenes;
    -0021         end
    -0022 
    -0023         function uniprotIDs = getUniprotIDsFromTable(obj,modelGenes)
    -0024             conversionTable = fullfile(obj.params.path,'data','uniprotConversion.tsv');
    -0025             if exist(conversionTable,'file')
    -0026                 fID=fopen(conversionTable,'r');
    -0027                 conversionTable = textscan(fID,'%q %q','Delimiter','\t','HeaderLines',1);
    -0028                 fclose(fID);
    -0029 
    -0030                 modelIDs    = conversionTable{1,1};
    -0031                 uniprots    = conversionTable{1,2};
    -0032 
    -0033                 [a,b] = ismember(modelGenes,modelIDs);
    -0034 
    -0035                 uniprotIDs  = strings(numel(modelGenes),1);
    -0036                 uniprotIDs(a)  = uniprots(b(a));
    -0037                 disp('The model genes are matched to Uniprot via the table at data/uniprotConversion.tsv.')
    -0038             else
    -0039                 uniprotIDs = modelGenes;
    -0040             end
    -0041         end
    -0042 
    -0043         function folder = getBrendaDBFolder(obj)
    -0044             folder = fullfile(findGECKOroot(),'databases');
    -0045         end
    -0046 
    -0047         function x = getPhylDistStructPath(obj)
    -0048             x =  fullfile(findRAVENroot(),'external','kegg','keggPhylDist.mat');
    -0049         end
    -0050 
    -0051         % Define a model-specific function in the 'code' subfolder of the
    -0052         % project folder, that can constrain the model to anaerobic
    -0053         % conditions, and refer to this function in the modelAdapter. This
    -0054         % function is used when running bayesianSensitivityTuning.m (via
    -0055         % abc_max.m) if the fluxData has anaerobic conditions.
    -0056         function ecModel = makeModelAnaerobic(obj,ecModel)
    -0057             ecModel = ecModel;
    -0058         end
    -0059     end
    -0060 
    -0061     %To have the params public is a bit "ugly", but very practical
    -0062     %if we want to change a parameter
    -0063     properties (Access = public)
    -0064         params;
    -0065     end
    -0066 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/model_adapter/ModelAdapterManager.html b/doc/src/geckomat/model_adapter/ModelAdapterManager.html deleted file mode 100644 index b9c24361..00000000 --- a/doc/src/geckomat/model_adapter/ModelAdapterManager.html +++ /dev/null @@ -1,108 +0,0 @@ - - - - Description of ModelAdapterManager - - - - - - - - - -
    Home > src > geckomat > model_adapter > ModelAdapterManager.m
    - - - -

    ModelAdapterManager -

    - -

    PURPOSE ^

    -
    Abstract Base class for adapters for different species
    - -

    SYNOPSIS ^

    -
    This is a script file.
    - -

    DESCRIPTION ^

    -
    Abstract Base class for adapters for different species
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: - -This function is called by: - - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 %Abstract Base class for adapters for different species
    -0002 classdef ModelAdapterManager 
    -0003     methods(Static)
    -0004         function adapter = getAdapter(adapterPath, addToMatlabPath)
    -0005             if nargin < 2
    -0006                 addToMatlabPath = true;
    -0007             end
    -0008             
    -0009             [adapterFolder, adapterClassName, extension] = fileparts(adapterPath);
    -0010             if ~strcmp(extension, '.m')
    -0011                 error('Please provide the full path to the adapter file, including the file extension.');
    -0012             else
    -0013                 s = pathsep;
    -0014                 pathStr = [s, path, s];
    -0015                 onPath = contains(pathStr, [s, adapterFolder, s], 'IgnoreCase', ispc);
    -0016                 % Check if the folder is on the path
    -0017                 if ~onPath
    -0018                     if addToMatlabPath
    -0019                         addpath(adapterFolder);
    -0020                     else
    -0021                         printOrange(['WARNING: The adapter will not be on the MATLAB path, since addToMatlabPath is false\n' ...
    -0022                                      'and it is not currently on the path. Either set addToMatlabPath to true, fix this\n'...
    -0023                                      'manually before calling this function or make sure it is in current directory (not\n'...
    -0024                                      'recommended). If the class is not reachable throughout the entire GECKO use there will\n'...
    -0025                                      'be errors throughout.\n']);
    -0026                     end
    -0027                 end
    -0028 
    -0029             end
    -0030             adapter = feval(adapterClassName);
    -0031         end
    -0032         
    -0033         function out = getDefault()
    -0034             out = ModelAdapterManager.setGetDefault();
    -0035         end
    -0036         
    -0037         function adapter = setDefault(adapterPath, addToMatlabPath)
    -0038             if nargin < 1 || isempty(adapterPath)
    -0039                 adapter = ModelAdapterManager.setGetDefault(adapterPath);
    -0040                 return
    -0041             end
    -0042             if nargin < 2
    -0043                 addToMatlabPath = true;
    -0044             end
    -0045             adapter = ModelAdapterManager.setGetDefault(ModelAdapterManager.getAdapter(adapterPath, addToMatlabPath));
    -0046         end
    -0047         
    -0048     end
    -0049     methods(Static,Access = private)
    -0050         % This is how they recommend defining static variables in Matlab
    -0051         function out = setGetDefault(val)
    -0052             persistent defaultAdapter; %will be empty initially
    -0053             if nargin
    -0054                 defaultAdapter = val;
    -0055             end
    -0056             out = defaultAdapter;
    -0057         end
    -0058     end
    -0059 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/model_adapter/adapterTemplate.html b/doc/src/geckomat/model_adapter/adapterTemplate.html deleted file mode 100644 index 75e6ad25..00000000 --- a/doc/src/geckomat/model_adapter/adapterTemplate.html +++ /dev/null @@ -1,139 +0,0 @@ - - - - Description of adapterTemplate - - - - - - - - - -
    Home > src > geckomat > model_adapter > adapterTemplate.m
    - - - -

    adapterTemplate -

    - -

    PURPOSE ^

    -
    - -

    SYNOPSIS ^

    -
    This is a script file.
    - -

    DESCRIPTION ^

    -
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    • ModelAdapter Abstract Base class for adapters for different species
    -This function is called by: -
      -
    - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 classdef KEY_CLASSNAME < ModelAdapter
    -0002     methods
    -0003         function obj = KEY_CLASSNAME()
    -0004             % Set initial values of the obj.params - they can be changed by the user
    -0005             
    -0006             % Directory where all model-specific files and scripts are kept.
    -0007             % Is assumed to follow the GECKO-defined folder structure.
    -0008             obj.params.path = fullfile('KEY_PATH', 'KEY_NAME');
    -0009             addpath(fullfile(obj.params.path,'code'));
    -0010 
    -0011             % Path to the conventional GEM that this ecModel will be based on.
    -0012             obj.params.convGEM = fullfile(obj.params.path,'models','yourModel.xml');
    -0013 
    -0014             % Average enzyme saturation factor
    -0015             obj.params.sigma = 0.5;
    -0016 
    -0017             % Total protein content in the cell [g protein/gDw]
    -0018             obj.params.Ptot = 0.5;
    -0019 
    -0020             % Fraction of enzymes in the model [g enzyme/g protein]
    -0021             obj.params.f = 0.5;
    -0022             
    -0023             % Growth rate the model should be able to reach when not
    -0024             % constraint by nutrient uptake (e.g. max growth rate) [1/h]
    -0025             obj.params.gR_exp = 0.41;
    -0026 
    -0027             % Provide your organism scientific name
    -0028             obj.params.org_name = 'genus species';
    -0029             
    -0030             % Taxonomic identifier for Complex Portal
    -0031             obj.params.complex.taxonomicID = [];
    -0032 
    -0033             % Provide your organism KEGG ID, selected at
    -0034             % https://www.genome.jp/kegg/catalog/org_list.html
    -0035             obj.params.kegg.ID = 'sce';
    -0036             % Field for KEGG gene identifier; should match the gene
    -0037             % identifiers used in the model. With 'kegg', it takes the
    -0038             % default KEGG Entry identifier (for example YER023W here:
    -0039             % https://www.genome.jp/dbget-bin/www_bget?sce:YER023W).
    -0040             % Alternatively, gene identifiers from the "Other DBs" section
    -0041             % of the KEGG page can be selected. For example "NCBI-GeneID",
    -0042             % "UniProt", or "Ensembl". Not all DB entries are available for
    -0043             % all organisms and/or genes.
    -0044             obj.params.kegg.geneID = 'kegg';
    -0045 
    -0046             % Provide what identifier should be used to query UniProt.
    -0047             % Select proteome IDs at https://www.uniprot.org/proteomes/
    -0048             % or taxonomy IDs at https://www.uniprot.org/taxonomy.
    -0049             obj.params.uniprot.type = 'taxonomy'; % 'proteome' or 'taxonomy'
    -0050             obj.params.uniprot.ID = '559292'; % should match the ID type
    -0051             % Field for Uniprot gene ID - should match the gene ids used in the
    -0052             % model. It should be one of the "Returned Field" entries under
    -0053             % "Names & Taxonomy" at this page: https://www.uniprot.org/help/return_fields
    -0054             obj.params.uniprot.geneIDfield = 'gene_oln';
    -0055             % Whether only reviewed data from UniProt should be considered.
    -0056             % Reviewed data has highest confidence, but coverage might be (very)
    -0057             % low for non-model organisms
    -0058             obj.params.uniprot.reviewed = false;
    -0059 
    -0060             % Reaction ID for glucose exchange reaction (or other preferred carbon source)
    -0061             obj.params.c_source = 'r_1714'; 
    -0062 
    -0063             % Reaction ID for biomass pseudoreaction
    -0064             obj.params.bioRxn = 'r_4041';
    -0065 
    -0066             % Name of the compartment where the protein pseudometabolites
    -0067             % should be located (all be located in the same compartment,
    -0068             % this does not interfere with them catalyzing reactions in
    -0069             % different compartments). Typically, cytoplasm is chosen.
    -0070             obj.params.enzyme_comp = 'cytoplasm';
    -0071         end
    -0072 
    -0073         % function ecModel = makeModelAnaerobic(ecModel)
    -0074         %     % Define a model-specific function in the 'code' subfolder,
    -0075         %     % that can constrain the model to anaerobic conditions, and
    -0076         %     % include the name of this function here. This is used by
    -0077         %     % bayesianSensitivityTuning.m (via abc_max.m) if the fluxData
    -0078         %     % has anaerobic conditions.
    -0079         %     addpath(fullfile(obj.params.path,'code'));
    -0080         %     ecModel = nameOfModelSpecificFunction(ecModel);
    -0081         % end
    -0082 
    -0083         function [spont,spontRxnNames] = getSpontaneousReactions(obj,model)
    -0084             % Indicates how spontaneous reactions are identified. Here it
    -0085             % is done by the reaction have 'spontaneous' in its name.
    -0086             spont = contains(model.rxnNames,'spontaneous');
    -0087             spontRxnNames = model.rxnNames(spont);
    -0088         end
    -0089     end
    -0090 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/model_adapter/index.html b/doc/src/geckomat/model_adapter/index.html deleted file mode 100644 index c588875b..00000000 --- a/doc/src/geckomat/model_adapter/index.html +++ /dev/null @@ -1,29 +0,0 @@ - - - - Index for Directory src\geckomat\model_adapter - - - - - - - - - - -
    < Master indexIndex for src\geckomat\model_adapter >
    - -

    Index for src\geckomat\model_adapter

    - -

    Matlab files in this directory:

    - -
     ModelAdapterAbstract Base class for adapters for different species
     ModelAdapterManagerAbstract Base class for adapters for different species
     adapterTemplate
    - - - - -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/addNewRxnsToEC.html b/doc/src/geckomat/utilities/addNewRxnsToEC.html deleted file mode 100644 index 8a416f8d..00000000 --- a/doc/src/geckomat/utilities/addNewRxnsToEC.html +++ /dev/null @@ -1,322 +0,0 @@ - - - - Description of addNewRxnsToEC - - - - - - - - - -
    Home > src > geckomat > utilities > addNewRxnsToEC.m
    - - - -

    addNewRxnsToEC -

    - -

    PURPOSE ^

    -
    addNewRxnsToEC
    - -

    SYNOPSIS ^

    -
    function [model, rxnsAdded, enzAdded] = addNewRxnsToEC(model, newRxns, newEnzymes, modelAdapter)
    - -

    DESCRIPTION ^

    -
     addNewRxnsToEC
    -   Add new reaction to an enzyme-constrained model. This function is 
    -   useful to simulate metabolic manipulations done to an organism such as
    -   integration of new genes that add a new reaction/pathway.
    -
    - Input:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   newRxns         structure with the new reaction information as follow:
    -                   rxns        cell array with unique strings that
    -                               identifies each reaction
    -                   rxnNames    cell array with the names of each reaction
    -                   equations   cell array with equation strings. Decimal
    -                               coefficients are expressed as "1.2".
    -                               Reversibility is indicated by "<=>" or
    -                               "=>".
    -                   grRules     cell array with the gene-reaction
    -                               relationship for each reaction. For example
    -                               "(A and B) or (C)" means that the reaction
    -                               could be catalyzed by a complex between
    -                               A & B or by C on its own. All the genes
    -                               have to be present in model.genes. Add
    -                               genes with addGenesRaven before calling
    -                               this function if needed (opt, default '')
    -   newEnzymes      structure with the new enzymes information as follow:
    -                   enzymes     cell array with uniprot id
    -                   genes       cell array with the respective gene
    -                   mw          cell array with the MW
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -                   default model adapter).
    -
    - Output:
    -   model           ecModel whit new reactions
    -   rxnsAdded       cell array with the reactions added
    -
    - Notes:
    -     (i) Write equations as follows:
    -               'xylitol[c] + NAD[c] => D-xylulose[c] + NADH[c] + H+[c]'
    -         Note that the reversibility defined in the equation will be used
    -         to split to construct irreversible reactions (add _REV) and the
    -         rules defined will be used to expand the model (add _EXP_n).
    -        
    -     (2) After add the new reactions, setKcatForReactions or
    -         applyCustomKcats should be run to add the kcat to the reactions,
    -         and subsequently applyKcatConstraints.
    -
    - Usage:
    -   [model, rxnsAdded, enzAdded] = addNewRxnsToEC(model, newRxns, newEnzymes, modelAdapter);
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function [model, rxnsAdded, enzAdded] = addNewRxnsToEC(model, newRxns, newEnzymes, modelAdapter)
    -0002 % addNewRxnsToEC
    -0003 %   Add new reaction to an enzyme-constrained model. This function is
    -0004 %   useful to simulate metabolic manipulations done to an organism such as
    -0005 %   integration of new genes that add a new reaction/pathway.
    -0006 %
    -0007 % Input:
    -0008 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0009 %   newRxns         structure with the new reaction information as follow:
    -0010 %                   rxns        cell array with unique strings that
    -0011 %                               identifies each reaction
    -0012 %                   rxnNames    cell array with the names of each reaction
    -0013 %                   equations   cell array with equation strings. Decimal
    -0014 %                               coefficients are expressed as "1.2".
    -0015 %                               Reversibility is indicated by "<=>" or
    -0016 %                               "=>".
    -0017 %                   grRules     cell array with the gene-reaction
    -0018 %                               relationship for each reaction. For example
    -0019 %                               "(A and B) or (C)" means that the reaction
    -0020 %                               could be catalyzed by a complex between
    -0021 %                               A & B or by C on its own. All the genes
    -0022 %                               have to be present in model.genes. Add
    -0023 %                               genes with addGenesRaven before calling
    -0024 %                               this function if needed (opt, default '')
    -0025 %   newEnzymes      structure with the new enzymes information as follow:
    -0026 %                   enzymes     cell array with uniprot id
    -0027 %                   genes       cell array with the respective gene
    -0028 %                   mw          cell array with the MW
    -0029 %   modelAdapter    a loaded model adapter (Optional, will otherwise use the
    -0030 %                   default model adapter).
    -0031 %
    -0032 % Output:
    -0033 %   model           ecModel whit new reactions
    -0034 %   rxnsAdded       cell array with the reactions added
    -0035 %
    -0036 % Notes:
    -0037 %     (i) Write equations as follows:
    -0038 %               'xylitol[c] + NAD[c] => D-xylulose[c] + NADH[c] + H+[c]'
    -0039 %         Note that the reversibility defined in the equation will be used
    -0040 %         to split to construct irreversible reactions (add _REV) and the
    -0041 %         rules defined will be used to expand the model (add _EXP_n).
    -0042 %
    -0043 %     (2) After add the new reactions, setKcatForReactions or
    -0044 %         applyCustomKcats should be run to add the kcat to the reactions,
    -0045 %         and subsequently applyKcatConstraints.
    -0046 %
    -0047 % Usage:
    -0048 %   [model, rxnsAdded, enzAdded] = addNewRxnsToEC(model, newRxns, newEnzymes, modelAdapter);
    -0049 
    -0050 if nargin < 4 || isempty(modelAdapter)
    -0051     modelAdapter = ModelAdapterManager.getDefault();
    -0052     if isempty(modelAdapter)
    -0053         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0054     end
    -0055 end
    -0056 params = modelAdapter.getParameters();
    -0057 
    -0058 if nargin < 3 || isempty(newEnzymes)
    -0059     newEnzymes = [];
    -0060 end
    -0061 
    -0062 % Validate if GECKO version 3
    -0063 if ~isfield(model, 'ec')
    -0064     error('Input model is not an ecModel in GECKO 3 format (with ecModel.ec structure)')
    -0065 end
    -0066 
    -0067 if model.ec.geckoLight
    -0068     error('addNewRxnsToEC only works on non-light ecModels')
    -0069 else
    -0070     % Check if the new proteins are not already present in the model
    -0071     if ~isempty(newEnzymes)
    -0072         [toRemove,~] = ismember(newEnzymes.enzymes, model.ec.enzymes);
    -0073 
    -0074         % Remove from the list those enzymes that already present
    -0075         if any(toRemove)
    -0076             printOrange(['WARNING: Enzymes ' strjoin(newEnzymes.enzymes(toRemove),', ') ' are already present in the model and will not be added.\n']);
    -0077             newEnzymes.enzymes(toRemove) = [];
    -0078             newEnzymes.genes(toRemove) = [];
    -0079             newEnzymes.mw(toRemove) = [];
    -0080         end
    -0081 
    -0082         if ~isempty(newEnzymes.enzymes)
    -0083             
    -0084             % 1. Add new genes
    -0085             genesToAdd.genes = newEnzymes.genes;
    -0086             genesToAdd.geneShortNames = genesToAdd.genes;
    -0087             model = addGenesRaven(model, genesToAdd);
    -0088 
    -0089             % 2. Add new Enzyme-usage pseudometabolite
    -0090 
    -0091             % Validate compartment to add protein pseudoreactions
    -0092             compartmentID = strcmp(model.compNames,params.enzyme_comp);
    -0093             if ~any(compartmentID)
    -0094                 error(['Compartment ' params.enzyme_comp ' (specified in params.enzyme_comp) '...
    -0095                     'cannot be found in model.compNames'])
    -0096             end
    -0097             compartmentID = model.comps(compartmentID);
    -0098 
    -0099             proteinMets.mets         = strcat('prot_', newEnzymes.enzymes);
    -0100             proteinMets.metNames     = proteinMets.mets;
    -0101             proteinMets.compartments = compartmentID;
    -0102             if isfield(model,'metMiriams')
    -0103                 proteinMets.metMiriams = repmat({struct('name',{{'sbo'}},'value',{{'SBO:0000252'}})},numel(proteinMets.mets),1);
    -0104             end
    -0105             if isfield(model,'metCharges')
    -0106                 proteinMets.metCharges = zeros(numel(proteinMets.mets),1);
    -0107             end
    -0108             proteinMets.metNotes = repmat({'Enzyme-usage pseudometabolite'},numel(proteinMets.mets),1);
    -0109             model = addMets(model,proteinMets);
    -0110         end
    -0111         enzAdded = newEnzymes.enzymes(:);  
    -0112     end
    -0113 
    -0114     % 3. Add new reactions
    -0115 
    -0116     % Before add the reactions validate that all the genes in grRules are
    -0117     % present in the model.
    -0118     genesInRules = strjoin(convertCharArray(newRxns.grRules));
    -0119     genesInRules = regexp(genesInRules,' |)|(|and|or','split'); % Remove all grRule punctuation
    -0120     genesInRules = genesInRules(~cellfun(@isempty,genesInRules));  % Remove spaces and empty genes
    -0121     genesInRules = setdiff(unique(genesInRules),model.genes); % Only keep new genes
    -0122 
    -0123     % If there is any gene which is not present, as to be pass as
    -0124     % newEnzymes input
    -0125     if ~isempty(genesInRules)
    -0126         errorText = 'The following genes from grRules are not present in the model, add them as newEnzymes input:';
    -0127         dispEM(errorText,true,genesInRules,false)
    -0128     end
    -0129 
    -0130     % Get reversible reactions to split
    -0131     toIrrev = find(cellfun(@(x) contains(x,'<=>'),newRxns.equations));
    -0132     if ~isempty(toIrrev)
    -0133         for i=1:numel(toIrrev)
    -0134             idx = toIrrev(i);
    -0135             newEquation = split(newRxns.equations(idx),'<=>');
    -0136             % Remove directionality
    -0137             newRxns.equations(idx) = erase(newRxns.equations(idx), '<');
    -0138 
    -0139             % Add a new reaction to the list to be added
    -0140             newRxns.rxns{end+1} = [newRxns.rxns{idx} '_REV'];
    -0141             newRxns.rxnNames{end+1} = [newRxns.rxnNames{idx} ' (reversible)'];
    -0142             newRxns.equations{end+1} = [strtrim(newEquation{2, 1}) ' => ' strtrim(newEquation{1, 1})];
    -0143             newRxns.grRules{end+1} = newRxns.grRules{idx};
    -0144         end
    -0145     end
    -0146 
    -0147     % Get reactions to separate isozymes
    -0148     toSplit = find(cellfun(@(x) contains(x,'or'),newRxns.grRules));
    -0149     if ~isempty(toSplit)
    -0150         for i=1:numel(toSplit)
    -0151             idx = toSplit(i);
    -0152             newRules = split(newRxns.grRules(idx),'or');
    -0153             newRules = strtrim(erase(newRules, {'(' ')'}));
    -0154 
    -0155             for j=1:numel(newRules)
    -0156                 newRxns.rxns{end+1} = [newRxns.rxns{idx} '_EXP_' num2str(j)];
    -0157                 newRxns.rxnNames(end+1) = newRxns.rxnNames(idx);
    -0158                 newRxns.equations(end+1) = newRxns.equations(idx);
    -0159                 newRxns.grRules(end+1) = newRules(j);
    -0160             end
    -0161 
    -0162             % Remove the original one
    -0163             newRxns.rxns(idx) = [];
    -0164             newRxns.rxnNames(idx) = [];
    -0165             newRxns.equations(idx) = [];
    -0166             newRxns.grRules(idx) = [];
    -0167         end
    -0168     end
    -0169 
    -0170     newRxns.lb = zeros(length(newRxns.rxns),1);
    -0171     newRxns.ub = zeros(length(newRxns.rxns),1) + 1000;
    -0172 
    -0173     model = addRxns(model, newRxns, 3, '', true, true);
    -0174 
    -0175     % 4. Add protein usage reactions.
    -0176     usageRxns.rxns            = strcat('usage_',proteinMets.mets);
    -0177     usageRxns.rxnNames        = usageRxns.rxns;
    -0178     usageRxns.mets            = cell(numel(usageRxns.rxns),1);
    -0179     usageRxns.stoichCoeffs    = cell(numel(usageRxns.rxns),1);
    -0180     for i=1:numel(usageRxns.mets)
    -0181         usageRxns.mets{i}         = {proteinMets.mets{i}, 'prot_pool'};
    -0182         usageRxns.stoichCoeffs{i} = [-1,1];
    -0183     end
    -0184     usageRxns.lb              = zeros(numel(usageRxns.rxns),1) - 1000;
    -0185     usageRxns.ub              = zeros(numel(usageRxns.rxns),1);
    -0186     usageRxns.rev             = ones(numel(usageRxns.rxns),1);
    -0187     usageRxns.grRules         = newEnzymes.genes;
    -0188     model = addRxns(model,usageRxns);
    -0189 
    -0190     % 5. Update .ec field with enzyme data
    -0191     model.ec.enzymes    = [model.ec.enzymes; newEnzymes.enzymes(:)];
    -0192     model.ec.genes      = [model.ec.genes; newEnzymes.genes(:)];
    -0193     model.ec.mw         = [model.ec.mw; newEnzymes.mw(:)];
    -0194     model.ec.sequence   = [model.ec.sequence; repmat({''},numel(newEnzymes.enzymes),1)]; 
    -0195     if isfield(model.ec,'concs')
    -0196         model.ec.concs  = [model.ec.concs; NaN(numel(newEnzymes.enzymes),1)];
    -0197     end
    -0198 
    -0199     % 6. Expand the enzyme rxns matrix
    -0200     rxnWithRule = find(~cellfun('isempty',newRxns.grRules));
    -0201 
    -0202     model.ec.rxnEnzMat =  [model.ec.rxnEnzMat, zeros(length(model.ec.rxns), length(newEnzymes.enzymes))]; % add n new enzymes
    -0203     model.ec.rxnEnzMat =  [model.ec.rxnEnzMat; zeros(length(rxnWithRule), length(model.ec.enzymes))]; % add n new rxns
    -0204 
    -0205     % 7. Update .ec field with rxn data
    -0206 
    -0207     % Get reactions to add
    -0208     numRxns = length(model.ec.rxns);
    -0209     for i = 1:numel(rxnWithRule)
    -0210         rxnIdx = rxnWithRule(i);
    -0211 
    -0212         model.ec.rxns(end+1)    = newRxns.rxns(rxnIdx);
    -0213         model.ec.kcat(end+1)    = 0;
    -0214         model.ec.source(end+1)  = {''};
    -0215         model.ec.notes(end+1)   = {''};
    -0216         model.ec.eccodes(end+1) = {''};
    -0217 
    -0218         % Get rules
    -0219         genes = newRxns.grRules(rxnIdx);
    -0220         genes = strtrim(erase(split(genes,'and'), {'(' ')'}));
    -0221         [~,enzIdx] = ismember(genes, model.ec.genes);
    -0222 
    -0223         % Update the enzyme rxns matrix
    -0224         model.ec.rxnEnzMat(numRxns+i, enzIdx) = 1;
    -0225     end
    -0226     
    -0227     rxnsAdded = newRxns.rxns(:);
    -0228 end
    -0229 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/ecFSEOF.html b/doc/src/geckomat/utilities/ecFSEOF.html deleted file mode 100644 index d6d4081f..00000000 --- a/doc/src/geckomat/utilities/ecFSEOF.html +++ /dev/null @@ -1,410 +0,0 @@ - - - - Description of ecFSEOF - - - - - - - - - -
    Home > src > geckomat > utilities > ecFSEOF.m
    - - - -

    ecFSEOF -

    - -

    PURPOSE ^

    -
    ecFSEOF
    - -

    SYNOPSIS ^

    -
    function fseof = ecFSEOF(model,prodTargetRxn,csRxn,nSteps,outputFile,filePath,modelAdapter)
    - -

    DESCRIPTION ^

    -
     ecFSEOF
    -   Function that runs Flux-Scanning with Enforced Objective Function (FSEOF)
    -   for a specified production target.
    -
    - Input:
    -   model          an ecModel in GECKO 3 format (with ecModel.ec structure).
    -   prodTargetRxn  rxn ID for the production target reaction, a exchange
    -                  reaction is recommended.
    -   csRxn          rxn ID for the main carbon source uptake reaction.
    -   nSteps         number of steps for suboptimal objective in FSEOF.
    -                  (Optional, default 16)
    -   outputFile     bolean option to save results in a file. (Optional,
    -                  default false)
    -   filePath       file path for results output. It will store two files:
    -                  - at the genes level, ecFSEOF_genes.tsv
    -                  - at the reactions level, ecFSEOF_rxns.tsv
    -                  (Optional, default in the 'output' sub-folder taken from
    -                  modelAdapter, e.g. output/ecFSEOF_rxns.tsv)
    -   modelAdapter   a loaded model adapter. (Optional, will otherwise use
    -                  the default model adapter)
    -
    - Output:
    -   fseof   an structure with all results. Contains the following fields:
    -           - alpha:             target production used for enforced 
    -                                objetive limits (from minimum to maximum 
    -                                production)
    -           - v_matrix:          fluxes for each target reaction predicted
    -                                and each alpha.
    -           - rxnTargets:        a list with all reactions with fluxes that
    -                                change consistently as target production
    -                                increases.
    -                                Contains: ID, name, slope, gene rule, and
    -                                equation
    -           - transportTargets:  a list with all transport reactions with
    -                                fluxes that change consistently as target
    -                                production increases.
    -                                Contains: ID, name, slope, gene rule, and
    -                                equation
    -           - geneTargets:       a list with all selected targets that
    -                                increase production.
    -                                Contains: gene, shortName, slope, action,
    -                                and essentiality
    -
    - Usage:
    -   fseof = ecFSEOF(model,prodTargetRxn,csRxn,nSteps,outputFile,filePath,filterG,modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function fseof = ecFSEOF(model,prodTargetRxn,csRxn,nSteps,outputFile,filePath,modelAdapter)
    -0002 % ecFSEOF
    -0003 %   Function that runs Flux-Scanning with Enforced Objective Function (FSEOF)
    -0004 %   for a specified production target.
    -0005 %
    -0006 % Input:
    -0007 %   model          an ecModel in GECKO 3 format (with ecModel.ec structure).
    -0008 %   prodTargetRxn  rxn ID for the production target reaction, a exchange
    -0009 %                  reaction is recommended.
    -0010 %   csRxn          rxn ID for the main carbon source uptake reaction.
    -0011 %   nSteps         number of steps for suboptimal objective in FSEOF.
    -0012 %                  (Optional, default 16)
    -0013 %   outputFile     bolean option to save results in a file. (Optional,
    -0014 %                  default false)
    -0015 %   filePath       file path for results output. It will store two files:
    -0016 %                  - at the genes level, ecFSEOF_genes.tsv
    -0017 %                  - at the reactions level, ecFSEOF_rxns.tsv
    -0018 %                  (Optional, default in the 'output' sub-folder taken from
    -0019 %                  modelAdapter, e.g. output/ecFSEOF_rxns.tsv)
    -0020 %   modelAdapter   a loaded model adapter. (Optional, will otherwise use
    -0021 %                  the default model adapter)
    -0022 %
    -0023 % Output:
    -0024 %   fseof   an structure with all results. Contains the following fields:
    -0025 %           - alpha:             target production used for enforced
    -0026 %                                objetive limits (from minimum to maximum
    -0027 %                                production)
    -0028 %           - v_matrix:          fluxes for each target reaction predicted
    -0029 %                                and each alpha.
    -0030 %           - rxnTargets:        a list with all reactions with fluxes that
    -0031 %                                change consistently as target production
    -0032 %                                increases.
    -0033 %                                Contains: ID, name, slope, gene rule, and
    -0034 %                                equation
    -0035 %           - transportTargets:  a list with all transport reactions with
    -0036 %                                fluxes that change consistently as target
    -0037 %                                production increases.
    -0038 %                                Contains: ID, name, slope, gene rule, and
    -0039 %                                equation
    -0040 %           - geneTargets:       a list with all selected targets that
    -0041 %                                increase production.
    -0042 %                                Contains: gene, shortName, slope, action,
    -0043 %                                and essentiality
    -0044 %
    -0045 % Usage:
    -0046 %   fseof = ecFSEOF(model,prodTargetRxn,csRxn,nSteps,outputFile,filePath,filterG,modelAdapter)
    -0047 
    -0048 if nargin < 7 || isempty(modelAdapter)
    -0049     modelAdapter = ModelAdapterManager.getDefault();
    -0050     if isempty(modelAdapter)
    -0051         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0052     end
    -0053 end
    -0054 params = modelAdapter.getParameters();
    -0055 
    -0056 if nargin < 5 || isempty(outputFile)
    -0057     outputFile = false;
    -0058 end
    -0059 
    -0060 if nargin < 6 || isempty(filePath)
    -0061     filePath = fullfile(params.path,'output');
    -0062 end
    -0063 
    -0064 if nargin < 4 || isempty(nSteps)
    -0065     nSteps = 16;
    -0066 end
    -0067 
    -0068 % Get relevant rxn indexes
    -0069 prodTargetRxnIdx = getIndexes(model, prodTargetRxn,'rxns');
    -0070 csRxnIdx         = getIndexes(model, csRxn,'rxns');
    -0071 bioRxnIdx        = getIndexes(model, params.bioRxn,'rxns');
    -0072 
    -0073 % Standardize grRules and rxnGeneMat in model
    -0074 [grRules,rxnGeneMat] = standardizeGrRules(model,true);
    -0075 model.grRules        = grRules;
    -0076 model.rxnGeneMat     = rxnGeneMat;
    -0077 
    -0078 % Check carbon source uptake rate and LB defined
    -0079 model = setParam(model, 'obj', params.bioRxn, 1);
    -0080 sol   = solveLP(model);
    -0081 if model.lb(csRxnIdx) < sol.x(csRxnIdx)
    -0082     printOrange(['WARNING: Carbon source lower bound was set to ' num2str(model.lb(csRxnIdx)) ...
    -0083         ', but the uptake rate after model optimization is ' num2str(sol.x(csRxnIdx)) '.\n']);
    -0084 end
    -0085 
    -0086 % run FSEOF analysis
    -0087 
    -0088 % Find out the initial target production.
    -0089 iniTarget = sol.x(prodTargetRxnIdx);
    -0090 
    -0091 % Find out the maximum theoretical yield of target reaction.
    -0092 model     = setParam(model,'obj',prodTargetRxn,1);
    -0093 sol       = solveLP(model,1);
    -0094 % Set to 90%% based on https://doi.org/10.1128/AEM.00115-10
    -0095 maxTarget = sol.x(prodTargetRxnIdx) * 0.9;
    -0096 
    -0097 % Define alpha vector for suboptimal enforced objective values between
    -0098 % minimal production and 90%% of the maximum theoretical yield, initialize
    -0099 % fluxes matriz
    -0100 alpha    = iniTarget:((maxTarget-iniTarget)/(nSteps-1)):maxTarget;
    -0101 v_matrix = zeros(length(model.rxns),length(alpha));
    -0102 
    -0103 % Enforce objective flux iteratively
    -0104 progressbar('Flux Scanning with Enforced Objective Function')
    -0105 for i = 1:nSteps
    -0106     % Enforce the objetive flux of product formation
    -0107     model = setParam(model,'eq',prodTargetRxnIdx,alpha(i));
    -0108 
    -0109     % Restore minimum biomass lb to zero and set it as objective
    -0110     model.lb(bioRxnIdx) = 0;
    -0111     model = setParam(model,'obj',params.bioRxn,1);
    -0112     sol   = solveLP(model,1);
    -0113 
    -0114     % Store flux distribution
    -0115     v_matrix(:,i) = sol.x;
    -0116 
    -0117     progressbar(i/nSteps)
    -0118 end
    -0119 progressbar(1) % Make sure it closes
    -0120 
    -0121 % Take out rxns with no grRule and standard gene
    -0122 withGR         = ~cellfun(@isempty,model.grRules);
    -0123 stdIdx         = contains(model.grRules,'standard');
    -0124 withGR(stdIdx) = 0;
    -0125 target_rxns    = model.rxns(withGR);
    -0126 v_matrix       = v_matrix(withGR,:);
    -0127 rxnGeneM       = model.rxnGeneMat(withGR,:);
    -0128 
    -0129 % Filter out rxns that are always zero
    -0130 zero_flux   = ~all(abs(v_matrix(:,1:nSteps))==0,2);
    -0131 target_rxns = target_rxns(zero_flux,:);
    -0132 v_matrix    = v_matrix(zero_flux,:);
    -0133 rxnGeneM    = rxnGeneM(zero_flux,:);
    -0134 
    -0135 % Identify those rxns that always increase or decrease, and calculate the
    -0136 % slope as the difference in the flux when enforce objetive target
    -0137 % production is set to 90%% of the maximum teorethical yield
    -0138 % << v_matrix(i,nSteps-1) >> and the flux when the enforce objetive target
    -0139 % production is set to the minimum << v_matrix(i,1) >> for the reaction i,
    -0140 % divided by maxTarget-maxTarget/nSteps-1.
    -0141 slope_rxns  = zeros(size(target_rxns));
    -0142 targets     = logical(size(target_rxns));
    -0143 target_type = cell(size(target_rxns));
    -0144 for i = 1:length(target_rxns)
    -0145     if issorted(abs(v_matrix(i,1:nSteps)),'strictascend')
    -0146         % Those reactions that always increase while enforcing target
    -0147         % production are suggested for Over Expression
    -0148         targets(i) = true;
    -0149         slope_rxns(i)  = abs(v_matrix(i,nSteps-1)-v_matrix(i,1))/abs(maxTarget-maxTarget/nSteps-1);
    -0150         target_type(i) = {'OE'};
    -0151     elseif issorted(abs(v_matrix(i,1:nSteps)),'strictdescend')
    -0152         % Those reactions that always decrease while enforcing target
    -0153         % production are suggested for KnockDown or KnockOut. KO are those
    -0154         % reactions which have zero flux when enforcing target production
    -0155         % to 90%% of the maximum theoretical yield.
    -0156         targets(i) = true;
    -0157         slope_rxns(i)  = abs(v_matrix(i,nSteps-1)-v_matrix(i,1))/abs(maxTarget-maxTarget/nSteps-1);
    -0158         if v_matrix(i,nSteps) == 0
    -0159             target_type(i) = {'KO'};
    -0160         else
    -0161             target_type(i) = {'KD'};
    -0162         end
    -0163     end
    -0164 end
    -0165 
    -0166 % Only keep those reaction that shows an increase or decrease pattern.
    -0167 target_rxns = target_rxns(targets);
    -0168 v_matrix    = v_matrix(targets,:);
    -0169 rxnGeneM    = rxnGeneM(targets,:);
    -0170 slope_rxns  = slope_rxns(targets);
    -0171 target_type = target_type(targets);
    -0172 
    -0173 % Order from highest to lowest slope
    -0174 [~,order]   = sort(slope_rxns,'descend');
    -0175 target_rxns = target_rxns(order);
    -0176 v_matrix    = v_matrix(order,:);
    -0177 rxnGeneM    = rxnGeneM(order,:);
    -0178 slope_rxns  = slope_rxns(order);
    -0179 target_type = target_type(order);
    -0180 
    -0181 % Filter out reactions with slope < quantile
    -0182 non_zero_slope  = slope_rxns > quantile(slope_rxns,0.75);
    -0183 target_rxns     = target_rxns(non_zero_slope);
    -0184 v_matrix        = v_matrix(non_zero_slope,:);
    -0185 rxnGeneM        = rxnGeneM(non_zero_slope,:);
    -0186 slope_rxns      = slope_rxns(non_zero_slope);
    -0187 target_type     = target_type(non_zero_slope);
    -0188 
    -0189 % Create gene list of those connected to the remaining rxns
    -0190 genes             = model.genes(sum(rxnGeneM,1) > 0);
    -0191 slope_genes       = zeros(size(genes));
    -0192 rxnGeneM          = rxnGeneM(:,sum(rxnGeneM,1) > 0);
    -0193 target_type_genes = cell(size(genes));
    -0194 essentiality      = cell(size(genes));
    -0195 
    -0196 % Validate for gene essentiality
    -0197 progressbar('Checking for gene essentiality')
    -0198 for i = 1:numel(genes)
    -0199 
    -0200     % Block protein usage to KO al the reactions associated to it.
    -0201     usage_rxn_idx = strcmpi(model.ec.genes, genes{i});
    -0202     usage_rxn = strcat('usage_prot_', model.ec.enzymes(usage_rxn_idx));
    -0203     tempModel = setParam(model, 'eq', usage_rxn, 0);
    -0204     solKO     = solveLP(tempModel);
    -0205     % Check if no feasible solution was found
    -0206     if solKO.stat == -1 || solKO.x(bioRxnIdx) < 1e-8
    -0207         essentiality(i) = {'essential'};
    -0208     end
    -0209 
    -0210     % Since a gene can be involved in multiple reactions, multiple
    -0211     % engineering manipulations can be suggested for the same gene
    -0212     % e.g. (OE and KD). So, reconcilie them, and report only one.
    -0213     
    -0214     % Get reaction index, in targets set, for each gene
    -0215     rxns_for_gene = find(rxnGeneM(:,i) > 0);
    -0216     actions = unique(target_type(rxns_for_gene));
    -0217     if numel(actions) > 1
    -0218         % If any OE is suggested give the highest priority over KD or KO
    -0219         if any(startsWith(actions, 'OE'))
    -0220             target_type_genes(i) = {'OE'};
    -0221             % Otherwise change to KO if not essential
    -0222         elseif ~any(startsWith(actions, 'OE')) && ~isequal(essentiality(i),{'essential'})
    -0223             target_type_genes(i) = {'KO'};
    -0224         else
    -0225             target_type_genes(i) = {'KD'};
    -0226         end
    -0227     else
    -0228         target_type_genes(i) = actions;
    -0229     end
    -0230     % Extract all the slope (from rxns across alphas) conected to
    -0231     % each remaining gene
    -0232     slope_set      = slope_rxns(rxns_for_gene);
    -0233     slope_genes(i) = mean(slope_set);
    -0234 
    -0235     progressbar(i/numel(genes))
    -0236 end
    -0237 progressbar(1) % Make sure it closes
    -0238 
    -0239 % Order genes from highest to lowest slope:
    -0240 [~,order]         = sort(slope_genes,'descend');
    -0241 genes             = genes(order,:);
    -0242 slope_genes       = slope_genes(order,:);
    -0243 target_type_genes = target_type_genes(order,:);
    -0244 essentiality      = essentiality(order,:);
    -0245 
    -0246 % Create output:
    -0247 
    -0248 % Report values used to enforce objective target production
    -0249 fseof.alpha = alpha;
    -0250 
    -0251 % Exclude enzyme usage reactions
    -0252 toKeep = ~startsWith(target_rxns,'usage_prot_');
    -0253 rxnIdx = getIndexes(model,target_rxns(toKeep),'rxns');
    -0254 
    -0255 % Report the fluxes at each alpha
    -0256 fseof.v_matrix = array2table(v_matrix(toKeep,:), ...
    -0257     'VariableNames', string(alpha), 'RowNames', model.rxns(rxnIdx));
    -0258 
    -0259 % Report reaction targets
    -0260 fseof.rxnTargets(:,1) = model.rxns(rxnIdx);
    -0261 fseof.rxnTargets(:,2) = model.rxnNames(rxnIdx);
    -0262 fseof.rxnTargets(:,3) = num2cell(slope_rxns(toKeep));
    -0263 fseof.rxnTargets(:,4) = model.grRules(rxnIdx);
    -0264 fseof.rxnTargets(:,5) = constructEquations(model,rxnIdx);
    -0265 
    -0266 % Identify transport reactions; defined as reactions involving (at least)
    -0267 % one metabolite name in more than one compartment.
    -0268 transportRxns = false(numel(rxnIdx),1);
    -0269 for i = 1:numel(rxnIdx)
    -0270     % Get the involved metabolites in each reaction
    -0271     mets = model.metNames(model.S(:,rxnIdx(i))~=0);
    -0272     % Remove enzyme metabolite
    -0273     mets(startsWith(mets,'prot_')) = [];
    -0274     % Validate if it is a transport reaciton
    -0275     transportRxns(i) = numel(mets) ~= numel(unique(mets));
    -0276 end
    -0277 
    -0278 % Create separate table for transport reactions
    -0279 fseof.transportTargets = fseof.rxnTargets(transportRxns,:);
    -0280 fseof.rxnTargets(transportRxns,:) = [];
    -0281 
    -0282 % Report gene targets
    -0283 geneIdx              = cellfun(@(x) find(strcmpi(model.genes,x)),genes);
    -0284 fseof.geneTargets(:,1) = genes;
    -0285 fseof.geneTargets(:,2) = model.geneShortNames(geneIdx);
    -0286 fseof.geneTargets(:,3) = num2cell(slope_genes);
    -0287 fseof.geneTargets(:,4) = target_type_genes;
    -0288 fseof.geneTargets(:,5) = essentiality;
    -0289 
    -0290 % Save results in a file if defined
    -0291 if outputFile
    -0292     % Write file with gene targets
    -0293     writetable(cell2table(fseof.geneTargets, ...
    -0294         'VariableNames', {'gene_IDs' 'gene_names' 'slope' 'action' 'essentiality'}), ...
    -0295         fullfile(filePath, 'ecFSEOF_genes.tsv'), ...
    -0296         'FileType', 'text', ...
    -0297         'Delimiter', '\t', ...
    -0298         'QuoteStrings', false);
    -0299 
    -0300     % Write file with rxn targets
    -0301     writetable(cell2table(fseof.rxnTargets, ...
    -0302         'VariableNames', {'rxn_IDs' 'rxnNames' 'slope' 'grRules' 'rxn_formula'}), ...
    -0303         fullfile(filePath, 'ecFSEOF_rxns.tsv'), ...
    -0304         'FileType', 'text', ...
    -0305         'Delimiter', '\t', ...
    -0306         'QuoteStrings', false);
    -0307 
    -0308     % Write file with transport targets
    -0309     writetable(cell2table(fseof.transportTargets, ...
    -0310         'VariableNames', {'rxn_IDs' 'rxnNames' 'slope' 'grRules' 'rxn_formula'}), ...
    -0311         fullfile(filePath, 'ecFSEOF_transporter.tsv'), ...
    -0312         'FileType', 'text', ...
    -0313         'Delimiter', '\t', ...
    -0314         'QuoteStrings', false);
    -0315 
    -0316     disp(['ecFSEOF results stored at: ' newline filePath]);
    -0317 end
    -0318 
    -0319 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/ecFVA.html b/doc/src/geckomat/utilities/ecFVA.html deleted file mode 100644 index 110325d0..00000000 --- a/doc/src/geckomat/utilities/ecFVA.html +++ /dev/null @@ -1,146 +0,0 @@ - - - - Description of ecFVA - - - - - - - - - -
    Home > src > geckomat > utilities > ecFVA.m
    - - - -

    ecFVA -

    - -

    PURPOSE ^

    -
    ecFVA
    - -

    SYNOPSIS ^

    -
    function [minFlux, maxFlux] = ecFVA(ecModel, model)
    - -

    DESCRIPTION ^

    -
     ecFVA
    -   Flux variability analysis is performed on the ecModel, and isozymic
    -   reactions are combined to construct ouput minFlux and maxFlux vectors,
    -   which follow the same order of model.rxns. The output from this
    -   function does not include enzyme usage reactions, to observe these, on
    -   could consider running flux variability directly on the ecModel.
    -
    - Input:
    -   ecModel     an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   model       non-ecModel variant of the ecModel, to which the minFlux
    -               and maxFlux will be mapped
    - Output:
    -   minFlux     vector of minimum flux rates, corresponding to model.rxns
    -   maxFlux     vector of maximum flux rates, corresponding to model.rxns
    -
    - Usage: [minFlux, maxFlux] = ecFVA(ecModel, model)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: - -This function is called by: -
      -
    - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 function [minFlux, maxFlux] = ecFVA(ecModel, model)
    -0002 % ecFVA
    -0003 %   Flux variability analysis is performed on the ecModel, and isozymic
    -0004 %   reactions are combined to construct ouput minFlux and maxFlux vectors,
    -0005 %   which follow the same order of model.rxns. The output from this
    -0006 %   function does not include enzyme usage reactions, to observe these, on
    -0007 %   could consider running flux variability directly on the ecModel.
    -0008 %
    -0009 % Input:
    -0010 %   ecModel     an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0011 %   model       non-ecModel variant of the ecModel, to which the minFlux
    -0012 %               and maxFlux will be mapped
    -0013 % Output:
    -0014 %   minFlux     vector of minimum flux rates, corresponding to model.rxns
    -0015 %   maxFlux     vector of maximum flux rates, corresponding to model.rxns
    -0016 %
    -0017 % Usage: [minFlux, maxFlux] = ecFVA(ecModel, model)
    -0018 
    -0019 rxnIDs = regexprep(ecModel.rxns,'(_REV)?(_EXP_\d+)?','');
    -0020 [rxnIDmap, convRxnID] = findgroups(rxnIDs);
    -0021 
    -0022 solMaxAll = nan(numel(ecModel.rxns),numel(convRxnID));
    -0023 solMinAll = solMaxAll;
    -0024 
    -0025 pool = gcp('nocreate');
    -0026 if isempty(pool)
    -0027     parpool;
    -0028 end
    -0029 
    -0030 D = parallel.pool.DataQueue;
    -0031 progressbar('Running ecFVA');
    -0032 afterEach(D, @nUpdateProgressbar);
    -0033 
    -0034 N = numel(convRxnID);
    -0035 p = 1;
    -0036 
    -0037 parfor i=1:N
    -0038     tmpModel = ecModel;
    -0039     tmpModel.c = zeros(numel(tmpModel.rxns),1);
    -0040 
    -0041     rxnsToOptim = find(rxnIDmap == i);
    -0042     rxnsOptIDs  = ecModel.rxns(rxnsToOptim);
    -0043     rxnsToMin = endsWith(rxnsOptIDs,'_REV') | contains(rxnsOptIDs,'_REV_EXP_');
    -0044     rxnsToMax = rxnsToOptim(~rxnsToMin);
    -0045     rxnsToMin = rxnsToOptim(rxnsToMin);
    -0046 
    -0047     tmpModel.c(rxnsToMax) = 1;
    -0048     tmpModel.c(rxnsToMin) = -1;
    -0049     solMax=solveLP(tmpModel);
    -0050     if ~isempty(solMax.x)
    -0051         solMaxAll(:,i)=solMax.x;
    -0052     end
    -0053     tmpModel.c(rxnsToMax) = -1;
    -0054     tmpModel.c(rxnsToMin) = 1;
    -0055     solMin=solveLP(tmpModel);
    -0056     if ~isempty(solMin.x)
    -0057         solMinAll(:,i)=solMin.x;
    -0058     end    
    -0059     send(D, i);
    -0060 end
    -0061 
    -0062 minFlux=min(solMinAll,[],2,'omitnan');
    -0063 maxFlux=max(solMaxAll,[],2,'omitnan');
    -0064 
    -0065 mappedFlux = mapRxnsToConv(ecModel,model,[minFlux maxFlux]);
    -0066 
    -0067 minFlux=mappedFlux(:,1);
    -0068 maxFlux=mappedFlux(:,2);
    -0069 
    -0070 % Mapped flux might have swapped directionality: min/max might be swapped
    -0071 swapDir = minFlux > maxFlux;
    -0072 if any(swapDir)
    -0073     tmpFlux = minFlux(swapDir);
    -0074     minFlux(swapDir) = maxFlux(swapDir);
    -0075     maxFlux(swapDir) = tmpFlux;
    -0076 end
    -0077 
    -0078 function nUpdateProgressbar(~)
    -0079 progressbar(p/N);
    -0080 p = p + 1;
    -0081 end
    -0082 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/enzymeUsage.html b/doc/src/geckomat/utilities/enzymeUsage.html deleted file mode 100644 index 012d491c..00000000 --- a/doc/src/geckomat/utilities/enzymeUsage.html +++ /dev/null @@ -1,132 +0,0 @@ - - - - Description of enzymeUsage - - - - - - - - - -
    Home > src > geckomat > utilities > enzymeUsage.m
    - - - -

    enzymeUsage -

    - -

    PURPOSE ^

    -
    enzymeUsage
    - -

    SYNOPSIS ^

    -
    function usageData = enzymeUsage(ecModel,fluxes,zero)
    - -

    DESCRIPTION ^

    -
     enzymeUsage
    -   Gives enzyme usages based on a provided flux distribution, as obtained
    -   from a full GECKO model. It can give:
    -   1)  absolute usage: the specific enzyme usage in mg/gDCW, which can
    -       be given for enzymes with- and without concentration information;
    -   2)  capacity usage: the ratio of available enzyme that is used, calcuted
    -       by (absUsage/UB) (note that capacity usage is 0 if an enzyme
    -       concentration was not constrained in the model);
    -   3)  UB: the upper bound of each enzyme exchange reaction, which may not
    -       be the same as the enzyme concentration, if it has been
    -       flexibilized
    -   4)  protID: the protein identifiers for each enzyme (if the model has an
    -       enzymes field than this order is used, otherwise it is given
    -       alphabetically.
    -
    - Input:
    -   ecModel     an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   fluxes      vector of fluxes, for instance sol.x
    -   zero        logical whether also enzymes with zero absolute usage
    -               should be included (Optional, default true)
    -
    - Output:
    -   usageData   structure with enzyme usage data
    -               capUsage    vector of enzyme capacity usages
    -               absUsage    vector of absolute enzyme usages
    -               UB          vector of enzyme exchange reaction upper bounds
    -               protID      string array of matching protein IDs
    -               fluxes      vector of fluxes, copy of input fluxes
    -
    - Usage:
    -   usageData = enzymeUsage(ecModel,fluxes,zero)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function usageData = enzymeUsage(ecModel,fluxes,zero)
    -0002 % enzymeUsage
    -0003 %   Gives enzyme usages based on a provided flux distribution, as obtained
    -0004 %   from a full GECKO model. It can give:
    -0005 %   1)  absolute usage: the specific enzyme usage in mg/gDCW, which can
    -0006 %       be given for enzymes with- and without concentration information;
    -0007 %   2)  capacity usage: the ratio of available enzyme that is used, calcuted
    -0008 %       by (absUsage/UB) (note that capacity usage is 0 if an enzyme
    -0009 %       concentration was not constrained in the model);
    -0010 %   3)  UB: the upper bound of each enzyme exchange reaction, which may not
    -0011 %       be the same as the enzyme concentration, if it has been
    -0012 %       flexibilized
    -0013 %   4)  protID: the protein identifiers for each enzyme (if the model has an
    -0014 %       enzymes field than this order is used, otherwise it is given
    -0015 %       alphabetically.
    -0016 %
    -0017 % Input:
    -0018 %   ecModel     an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0019 %   fluxes      vector of fluxes, for instance sol.x
    -0020 %   zero        logical whether also enzymes with zero absolute usage
    -0021 %               should be included (Optional, default true)
    -0022 %
    -0023 % Output:
    -0024 %   usageData   structure with enzyme usage data
    -0025 %               capUsage    vector of enzyme capacity usages
    -0026 %               absUsage    vector of absolute enzyme usages
    -0027 %               UB          vector of enzyme exchange reaction upper bounds
    -0028 %               protID      string array of matching protein IDs
    -0029 %               fluxes      vector of fluxes, copy of input fluxes
    -0030 %
    -0031 % Usage:
    -0032 %   usageData = enzymeUsage(ecModel,fluxes,zero)
    -0033 
    -0034 if nargin<3
    -0035     zero=true;
    -0036 end
    -0037 if ecModel.ec.geckoLight
    -0038     error('This function does not work on GECKO light models.')
    -0039 end
    -0040 usageData.protID      = ecModel.ec.enzymes;
    -0041 [~,rxnIdx] = ismember(strcat('usage_prot_',ecModel.ec.enzymes),ecModel.rxns);
    -0042 
    -0043 usageData.LB          = ecModel.lb(rxnIdx);
    -0044 usageData.absUsage    = abs(fluxes(rxnIdx));
    -0045 usageData.capUsage    = abs(usageData.absUsage./usageData.LB);
    -0046 usageData.fluxes      = fluxes;
    -0047 
    -0048 if ~zero
    -0049     nonzero               = usageData.absUsage<0;
    -0050     usageData.absUsage    = usageData.absUsage(nonzero);
    -0051     usageData.capUsage    = usageData.capUsage(nonzero);
    -0052     usageData.LB          = usageData.LB(nonzero);
    -0053     usageData.protID      = usageData.protID(nonzero);
    -0054 end
    -0055 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/findGECKOroot.html b/doc/src/geckomat/utilities/findGECKOroot.html deleted file mode 100644 index 0c4d1709..00000000 --- a/doc/src/geckomat/utilities/findGECKOroot.html +++ /dev/null @@ -1,74 +0,0 @@ - - - - Description of findGECKOroot - - - - - - - - - -
    Home > src > geckomat > utilities > findGECKOroot.m
    - - - -

    findGECKOroot -

    - -

    PURPOSE ^

    -
    findGECKOroot
    - -

    SYNOPSIS ^

    -
    function [geckoPath, prevDir] = findGECKOroot()
    - -

    DESCRIPTION ^

    -
     findGECKOroot
    -   Finds the root of the GECKO directory, by searching for the path to
    -   GECKO.png. Can also record the current directory, in case a function will
    -   use the geckoPath to navigate to a precise folder, and it should return to
    -   the previous directory afterwards.
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: - - - - - -

    SOURCE CODE ^

    -
    0001 function [geckoPath, prevDir] = findGECKOroot()
    -0002 % findGECKOroot
    -0003 %   Finds the root of the GECKO directory, by searching for the path to
    -0004 %   GECKO.png. Can also record the current directory, in case a function will
    -0005 %   use the geckoPath to navigate to a precise folder, and it should return to
    -0006 %   the previous directory afterwards.
    -0007 
    -0008 ST=dbstack('-completenames');
    -0009 prevDir = pwd();
    -0010 geckoPath = ST(strcmp({ST.name},'findGECKOroot')).file;
    -0011 rootFound = 0;
    -0012 while rootFound == 0
    -0013     isRoot = exist(fullfile(geckoPath,'GECKOInstaller.m'),'file');
    -0014     if isRoot == 2
    -0015         rootFound = 1;
    -0016     else
    -0017         ravenPathOld = geckoPath;
    -0018         geckoPath = fileparts(geckoPath);
    -0019         if strcmp(ravenPathOld,geckoPath)
    -0020             error('Cannot find the GECKO root directory. Make sure you have not removed the GECKOInstaller.m file from your GECKO installation.')
    -0021         end
    -0022     end
    -0023 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/getSubsetEcModel.html b/doc/src/geckomat/utilities/getSubsetEcModel.html deleted file mode 100644 index a03f28c2..00000000 --- a/doc/src/geckomat/utilities/getSubsetEcModel.html +++ /dev/null @@ -1,139 +0,0 @@ - - - - Description of getSubsetEcModel - - - - - - - - - -
    Home > src > geckomat > utilities > getSubsetEcModel.m
    - - - -

    getSubsetEcModel -

    - -

    PURPOSE ^

    -
    getSubset_ecModel
    - -

    SYNOPSIS ^

    -
    function smallEcModel = getSubsetEcModel(bigEcModel,smallGEM)
    - -

    DESCRIPTION ^

    -
     getSubset_ecModel
    -   Generate a context-specific ecModel (strain/cell-line/tissue) by
    -   mapping reactions and genes from a conventional context-specific GEM to
    -   a general ecModel (bigEcModel), to yield a context-specific ecModel.
    -
    -   Both models (bigEcModel and the smallGEM) should have derived from the
    -   same starting model. If an ecModel with human-GEM 1.15.0 is made
    -   (yielding the bigEcModel), then human-GEM 1.15.0 should also be the
    -   basis from which the context-specific GEM (smallGEM) was generated by
    -   for instance tINIT.
    - 
    - Input:
    -   bigEcModel  enzyme-constrained version of conventional model of
    -                  metabolism for a given species
    -   smallGEM       Reduced model (subset of the general model) for a
    -                  specific strain (microbes) or cell-line/tissues (mammals)
    - 
    - Output:
    -   smallEcModel  Enzyme-constrained version of the context-specific model
    - 
    - Usage: smallEcModel = getSubsetEcModel(smallGEM,bigEcModel)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function smallEcModel = getSubsetEcModel(bigEcModel,smallGEM)
    -0002 % getSubset_ecModel
    -0003 %   Generate a context-specific ecModel (strain/cell-line/tissue) by
    -0004 %   mapping reactions and genes from a conventional context-specific GEM to
    -0005 %   a general ecModel (bigEcModel), to yield a context-specific ecModel.
    -0006 %
    -0007 %   Both models (bigEcModel and the smallGEM) should have derived from the
    -0008 %   same starting model. If an ecModel with human-GEM 1.15.0 is made
    -0009 %   (yielding the bigEcModel), then human-GEM 1.15.0 should also be the
    -0010 %   basis from which the context-specific GEM (smallGEM) was generated by
    -0011 %   for instance tINIT.
    -0012 %
    -0013 % Input:
    -0014 %   bigEcModel  enzyme-constrained version of conventional model of
    -0015 %                  metabolism for a given species
    -0016 %   smallGEM       Reduced model (subset of the general model) for a
    -0017 %                  specific strain (microbes) or cell-line/tissues (mammals)
    -0018 %
    -0019 % Output:
    -0020 %   smallEcModel  Enzyme-constrained version of the context-specific model
    -0021 %
    -0022 % Usage: smallEcModel = getSubsetEcModel(smallGEM,bigEcModel)
    -0023 
    -0024 % Check if models were derived from the same starting GEM
    -0025 Rxn_format = regexprep(bigEcModel.rxns,'_REV|_EXP_\d+','');
    -0026 rxnsDiff = find(~ismember(smallGEM.rxns,Rxn_format));
    -0027 if numel(rxnsDiff) > 0
    -0028     dispEM(['While both models should have derived from the same starting ',...
    -0029             'GEM, the following reactions from smallGEM could not be found ',...
    -0030             'in bigEcModel:'],true,smallGEM.rxns(rxnsDiff),false);
    -0031 end
    -0032 
    -0033 % Check if original bigEcModel contains context-dependent protein constraints
    -0034 if any(bigEcModel.lb(startsWith(bigEcModel.rxns,'usage_prot_')) ~= -1000)
    -0035     printOrange(['WARNING: The bigEcModel is constraint by protein concentrations that are\n' ...
    -0036                  'likely not relevant in the constructed smallEcModel.\n']);
    -0037 end
    -0038 
    -0039 % Remove genes (and associated reactions) that are absent in smallGEM
    -0040 genesToRemove  = setdiff(bigEcModel.genes,smallGEM.genes);
    -0041 % If genesToRemove contains "standard", then remove this entry
    -0042 if ismember('standard', genesToRemove)
    -0043     genesToRemove(strcmp(genesToRemove, 'standard')) = [];
    -0044 end
    -0045 smallEcModel = removeGenes(bigEcModel,genesToRemove,true,true,false);
    -0046 
    -0047 % Remove genes from ec-structure
    -0048 enzToRemove = ismember(smallEcModel.ec.genes,genesToRemove);
    -0049 smallEcModel.ec.genes(enzToRemove)       = [];
    -0050 smallEcModel.ec.enzymes(enzToRemove)     = [];
    -0051 smallEcModel.ec.concs(enzToRemove)       = [];
    -0052 smallEcModel.ec.mw(enzToRemove)          = [];
    -0053 smallEcModel.ec.sequence(enzToRemove)    = [];
    -0054 smallEcModel.ec.rxnEnzMat(:,enzToRemove) = [];
    -0055 
    -0056 % Remove any reaction (except prot_ associated) that is absent from smallGEM
    -0057 trimRxns = regexprep(smallEcModel.rxns,'_REV|_EXP_\d+','');
    -0058 protRxns = startsWith(smallEcModel.rxns,{'usage_prot_','prot_pool_exchange'});
    -0059 keepRxns = ismember(trimRxns,smallGEM.rxns) | protRxns;
    -0060 smallEcModel = removeReactions(smallEcModel,~keepRxns, true, true, true);
    -0061 
    -0062 % Remove reactions from ec-structure
    -0063 ecRxnsToRemove = ~ismember(smallEcModel.ec.rxns,smallEcModel.rxns);
    -0064 
    -0065 smallEcModel.ec.rxns(ecRxnsToRemove)        = [];
    -0066 smallEcModel.ec.kcat(ecRxnsToRemove)        = [];
    -0067 smallEcModel.ec.source(ecRxnsToRemove)      = [];
    -0068 smallEcModel.ec.notes(ecRxnsToRemove)       = [];
    -0069 smallEcModel.ec.eccodes(ecRxnsToRemove)     = [];
    -0070 smallEcModel.ec.rxnEnzMat(ecRxnsToRemove,:) = [];
    -0071 end
    -0072
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/index.html b/doc/src/geckomat/utilities/index.html deleted file mode 100644 index fa531e36..00000000 --- a/doc/src/geckomat/utilities/index.html +++ /dev/null @@ -1,29 +0,0 @@ - - - - Index for Directory src\geckomat\utilities - - - - - - - - - - -
    < Master indexIndex for src\geckomat\utilities >
    - -

    Index for src\geckomat\utilities

    - -

    Matlab files in this directory:

    - -
     addNewRxnsToECaddNewRxnsToEC
     ecFSEOFecFSEOF
     ecFVAecFVA
     enzymeUsageenzymeUsage
     findGECKOrootfindGECKOroot
     getSubsetEcModelgetSubset_ecModel
     loadConventionalGEMloadConventionalGEM
     loadEcModelloadEcModel
     loadFluxDataloadFluxData
     loadProtDataloadProtData
     mapRxnsToConvmapRxnsToConv
     plotEcFVAplotEcFVA
     reportEnzymeUsagereportEnzymeUsage
     saveEcModelsaveECmodel
     startGECKOprojectstartGECKOproject
     updateGECKOdocupdateGeckoDoc
    - - - - -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/loadConventionalGEM.html b/doc/src/geckomat/utilities/loadConventionalGEM.html deleted file mode 100644 index eeca7996..00000000 --- a/doc/src/geckomat/utilities/loadConventionalGEM.html +++ /dev/null @@ -1,107 +0,0 @@ - - - - Description of loadConventionalGEM - - - - - - - - - -
    Home > src > geckomat > utilities > loadConventionalGEM.m
    - - - -

    loadConventionalGEM -

    - -

    PURPOSE ^

    -
    loadConventionalGEM
    - -

    SYNOPSIS ^

    -
    function model = loadConventionalGEM(filename, modelAdapter)
    - -

    DESCRIPTION ^

    -
     loadConventionalGEM
    -   Loads the conventional GEM (non-ecModel) from the location specified in
    -   the modelAdapter. By default, it looks in the models/ subdirectory of 
    -   the param.path specified in the modelAdapter. When loading
    -   conventional GEMs from other locations, one can directly use importModel.
    -
    - Input:
    -   filename        name of the model file, located in the the models/
    -                   subfolder of param.path as specified in the
    -                   modelAdapter (Optional, will otherwise use the
    -                   value specified as param.convGEM in the
    -                   modelAdapter)
    -   modelAdapter    a loaded model adapter, from where the model folder is
    -                   read (Optional, will otherwise use the default model adapter).
    -
    - Output:
    -   model           model in RAVEN format
    -
    - Usage:
    -   model = loadConventionalGEM(filename, modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function model = loadConventionalGEM(filename, modelAdapter)
    -0002 % loadConventionalGEM
    -0003 %   Loads the conventional GEM (non-ecModel) from the location specified in
    -0004 %   the modelAdapter. By default, it looks in the models/ subdirectory of
    -0005 %   the param.path specified in the modelAdapter. When loading
    -0006 %   conventional GEMs from other locations, one can directly use importModel.
    -0007 %
    -0008 % Input:
    -0009 %   filename        name of the model file, located in the the models/
    -0010 %                   subfolder of param.path as specified in the
    -0011 %                   modelAdapter (Optional, will otherwise use the
    -0012 %                   value specified as param.convGEM in the
    -0013 %                   modelAdapter)
    -0014 %   modelAdapter    a loaded model adapter, from where the model folder is
    -0015 %                   read (Optional, will otherwise use the default model adapter).
    -0016 %
    -0017 % Output:
    -0018 %   model           model in RAVEN format
    -0019 %
    -0020 % Usage:
    -0021 %   model = loadConventionalGEM(filename, modelAdapter)
    -0022 
    -0023 
    -0024 if nargin < 2 || isempty(modelAdapter)
    -0025     modelAdapter = ModelAdapterManager.getDefault();
    -0026     if isempty(modelAdapter)
    -0027         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0028     end
    -0029 end
    -0030 params = modelAdapter.getParameters();
    -0031 if nargin < 1 || isempty(filename)
    -0032     filename = params.convGEM;
    -0033 else
    -0034     filename = fullfile(params.path,'models',[filename, '.xml'])
    -0035 end
    -0036 
    -0037 if endsWith(filename,'.xml')
    -0038     model = importModel(filename);
    -0039 elseif endsWith(filename,'.yml')
    -0040     model = readYAMLmodel(filename);
    -0041 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/loadEcModel.html b/doc/src/geckomat/utilities/loadEcModel.html deleted file mode 100644 index 3654832c..00000000 --- a/doc/src/geckomat/utilities/loadEcModel.html +++ /dev/null @@ -1,112 +0,0 @@ - - - - Description of loadEcModel - - - - - - - - - -
    Home > src > geckomat > utilities > loadEcModel.m
    - - - -

    loadEcModel -

    - -

    PURPOSE ^

    -
    loadEcModel
    - -

    SYNOPSIS ^

    -
    function model = loadEcModel(filename, modelAdapter)
    - -

    DESCRIPTION ^

    -
     loadEcModel
    -   Loads the ecModel that matches the modelAdapter. By default, it loads
    -   the models/ecModel.yml in the directory specified as param.path in
    -   the modelAdapter. Alternative files in the same folder can be loaded by
    -   providing the appropriate filename. If loading models from other
    -   locations, one can directly use readYAMLmodel.
    -
    - Input:
    -   filename        name of the ecModel file (Optional, default 'ecModel.yml').
    -                   Fill should be located in the models/ subfolder of
    -                   param.path as specified in the modelAdapter.
    -   modelAdapter    a loaded model adapter, from where the model folder is
    -                   read (Optional, will otherwise use the default model adapter).
    -
    - Output:
    -   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -
    - Usage:
    -   model = loadEcModel(filename, modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function model = loadEcModel(filename, modelAdapter)
    -0002 % loadEcModel
    -0003 %   Loads the ecModel that matches the modelAdapter. By default, it loads
    -0004 %   the models/ecModel.yml in the directory specified as param.path in
    -0005 %   the modelAdapter. Alternative files in the same folder can be loaded by
    -0006 %   providing the appropriate filename. If loading models from other
    -0007 %   locations, one can directly use readYAMLmodel.
    -0008 %
    -0009 % Input:
    -0010 %   filename        name of the ecModel file (Optional, default 'ecModel.yml').
    -0011 %                   Fill should be located in the models/ subfolder of
    -0012 %                   param.path as specified in the modelAdapter.
    -0013 %   modelAdapter    a loaded model adapter, from where the model folder is
    -0014 %                   read (Optional, will otherwise use the default model adapter).
    -0015 %
    -0016 % Output:
    -0017 %   model           an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0018 %
    -0019 % Usage:
    -0020 %   model = loadEcModel(filename, modelAdapter)
    -0021 
    -0022 if nargin < 2 || isempty(modelAdapter)
    -0023     modelAdapter = ModelAdapterManager.getDefault();
    -0024     if isempty(modelAdapter)
    -0025         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0026     end
    -0027 end
    -0028 params = modelAdapter.getParameters();
    -0029 if nargin < 1 || isempty(filename)
    -0030     filename = 'ecModel.yml';
    -0031 else
    -0032 end
    -0033 
    -0034 if ~endsWith(filename,{'yml','yaml'})
    -0035     error(['ecModels should preferably be distributed in YAML file format, ', ...
    -0036            'as otherwise model content will be lost. If the model is in ', ...
    -0037            'SBML format, you can use the usual importModel function to load ', ...
    -0038            'this as any other genome-scale model.'])
    -0039 end
    -0040 
    -0041 filename = fullfile(params.path,'models',filename); 
    -0042 if endsWith(filename,{'yml','yaml'})
    -0043     model = readYAMLmodel(filename);
    -0044 elseif endsWith(filename,{'xml','sbml'})
    -0045     model = importModel(filename);
    -0046 end
    -0047 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/loadFluxData.html b/doc/src/geckomat/utilities/loadFluxData.html deleted file mode 100644 index dabf85c0..00000000 --- a/doc/src/geckomat/utilities/loadFluxData.html +++ /dev/null @@ -1,155 +0,0 @@ - - - - Description of loadFluxData - - - - - - - - - -
    Home > src > geckomat > utilities > loadFluxData.m
    - - - -

    loadFluxData -

    - -

    PURPOSE ^

    -
    loadFluxData
    - -

    SYNOPSIS ^

    -
    function fluxData = loadFluxData(fluxDataFile, modelAdapter)
    - -

    DESCRIPTION ^

    -
     loadFluxData
    -   Function that loads total protein measurements and flux data (exchange
    -   fluxes for carbon source,  O2, CO2, etc.)
    -
    - Input:
    -   fluxDataFile    path to file with flux data. (Optional, default
    -                   reads data/fluxData.tsv as specified in modelAdapter)
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use
    -                   the default model adapter)
    -
    - Output:
    -   fluxData                structure with flux data
    -       conds               sampling condition
    -       Ptot                total protein (g/gDCW)
    -       grRate              growth rate (1/h)
    -       exchFluxes          exchange fluxes (mmol/gDCWh)
    -       exchMets            exchanged metabolites, matching exchFluxes
    -       exchRxnIDs          exchange reaction IDs, matching exchMets
    -       bayesianRMSEweight  if column existed in fluxData.tsv, weights for
    -                           RMSE calculation in Bayesian kcat tuning
    -       source              if column existed in fluxData.tsv, description
    -                           where the data comes from
    -
    - Usage:
    -   fluxData = loadFluxData(fluxDataFile, modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function fluxData = loadFluxData(fluxDataFile, modelAdapter)
    -0002 % loadFluxData
    -0003 %   Function that loads total protein measurements and flux data (exchange
    -0004 %   fluxes for carbon source,  O2, CO2, etc.)
    -0005 %
    -0006 % Input:
    -0007 %   fluxDataFile    path to file with flux data. (Optional, default
    -0008 %                   reads data/fluxData.tsv as specified in modelAdapter)
    -0009 %   modelAdapter    a loaded model adapter (Optional, will otherwise use
    -0010 %                   the default model adapter)
    -0011 %
    -0012 % Output:
    -0013 %   fluxData                structure with flux data
    -0014 %       conds               sampling condition
    -0015 %       Ptot                total protein (g/gDCW)
    -0016 %       grRate              growth rate (1/h)
    -0017 %       exchFluxes          exchange fluxes (mmol/gDCWh)
    -0018 %       exchMets            exchanged metabolites, matching exchFluxes
    -0019 %       exchRxnIDs          exchange reaction IDs, matching exchMets
    -0020 %       bayesianRMSEweight  if column existed in fluxData.tsv, weights for
    -0021 %                           RMSE calculation in Bayesian kcat tuning
    -0022 %       source              if column existed in fluxData.tsv, description
    -0023 %                           where the data comes from
    -0024 %
    -0025 % Usage:
    -0026 %   fluxData = loadFluxData(fluxDataFile, modelAdapter)
    -0027 
    -0028 if nargin < 2 || isempty(modelAdapter)
    -0029     modelAdapter = ModelAdapterManager.getDefault();
    -0030     if isempty(modelAdapter)
    -0031         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0032     end
    -0033 end
    -0034 params = modelAdapter.getParameters();
    -0035 
    -0036 if nargin < 1 || isempty(fluxDataFile)
    -0037     fluxDataFile = fullfile(params.path,'data','fluxData.tsv');
    -0038 end
    -0039 
    -0040 %Load total protein content and flux data
    -0041 fID       = fopen(fluxDataFile);
    -0042 formatStr = '%s';
    -0043 data      = textscan(fID,formatStr,'Delimiter','\n');
    -0044 fclose(fID);
    -0045 fluxDataRaw  = [];
    -0046 for i=1:length(data{1})
    -0047     row      = data{1}(i);
    -0048     row      = strsplit(row{1},'\t');
    -0049     row      = row(1:end);
    -0050     fluxDataRaw = [fluxDataRaw; row]; 
    -0051 end
    -0052 if size(fluxDataRaw,2) == 0
    -0053     error('The input file %s is likely not tab-delimited.', fluxDataFile)
    -0054 end
    -0055 fluxData            = [];
    -0056 
    -0057 %Find additional fields
    -0058 extraFieldNames     = {'bayesianRMSEweight','source'};
    -0059 extraFieldNumeric   = [true,false];      
    -0060 [~, extraFields]    = ismember(extraFieldNames,fluxDataRaw(1,:));
    -0061 for i=1:numel(extraFields)
    -0062     if extraFields(1) ~= 0
    -0063         if extraFieldNumeric(i)
    -0064             fluxData.(extraFieldNames{i}) = str2double(fluxDataRaw(2:end,extraFields(i)));
    -0065         else
    -0066             fluxData.(extraFieldNames{i}) = fluxDataRaw(2:end,extraFields(i));
    -0067         end
    -0068     end
    -0069 end
    -0070 fluxDataRaw(:,extraFields) = [];
    -0071 
    -0072 %Extract observed byProduct names from file
    -0073 exchRxns = fluxDataRaw(1,4:end);
    -0074 exchMets = strtrim(regexprep(exchRxns,'(.*)\(.*\)$','$1'));
    -0075 exchRxns = regexprep(exchRxns,'.*\((.*)\)$','$1');
    -0076 
    -0077 fluxData.conds      = fluxDataRaw(2:end,1);
    -0078 fluxData.Ptot       = str2double(fluxDataRaw(2:end,2));
    -0079 fluxData.grRate     = str2double(fluxDataRaw(2:end,3));
    -0080 fluxData.exchFluxes = str2double(fluxDataRaw(2:end,4:end));
    -0081 %fluxData.exchFluxes(isnan(fluxData.exchFluxes)) = 0;
    -0082 fluxData.exchMets   = exchMets;
    -0083 fluxData.exchRxnIDs = exchRxns;
    -0084 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/loadProtData.html b/doc/src/geckomat/utilities/loadProtData.html deleted file mode 100644 index 7b5e599a..00000000 --- a/doc/src/geckomat/utilities/loadProtData.html +++ /dev/null @@ -1,245 +0,0 @@ - - - - Description of loadProtData - - - - - - - - - -
    Home > src > geckomat > utilities > loadProtData.m
    - - - -

    loadProtData -

    - -

    PURPOSE ^

    -
    loadProtData
    - -

    SYNOPSIS ^

    -
    function protData = loadProtData(replPerCond, protDataFile, filterData, modelAdapter, minVal, maxRSD, maxMissing, cutLowest, addStdevs)
    - -

    DESCRIPTION ^

    -
     loadProtData
    -   Function that loads absolute proteomics data (in mg/gDCW) and returns
    -   mean values across replicates for each condition in the data file. By
    -   default it also filters the data by various criteria, to remove
    -   uncertain data (see input parameters).
    -
    - Input:
    -   replPerCond     vector with number of replicates for each condition in
    -                   the dataset. Example: [3, 2] if first conditions has
    -                   triplicates and second condition has duplicates.
    -   protDataFile    path to file with proteomics data, where protein levels
    -                   are in mg/gDCW (Optional, default reads 
    -                   data/proteomics.tsv as specified in modelAdapter)
    -                   Alternatively, protDataFile can be a protData structure
    -                   that was previously made by loadProtdata.
    -   filterData      logical whether abundances should be filtered. If
    -                   false, minVal, maxRSD, maxMissing and addStdevs are not
    -                   considered. (Optional, default true)
    -   modelAdapter    a loaded model adapter (Optional, will otherwise use
    -                   the default model adapter)
    -   minVal          threshold of mean protein measurement per condition.
    -                   (Optional, default = 0)
    -   maxRSD          maximum relative standard per condition. (Optional,
    -                   default = 1)
    -   maxMissing      ratio of replicates for which a protein level might be
    -                   missing. (Optional, default = 1/3 (or 1/2 if number of
    -                   replicates = 2))
    -                   If conditions have different number of replicates (as
    -                   indicated in replPerCond), maxMissing can also be a
    -                   vector of the same length as replPerCond, with
    -                   individual maxMissing parameters for each replicate.
    -   cutLowest       percentage of lowest mean values per condition to be
    -                   discared (not considering NaN values). (Optional, default 5)
    -   addStdevs       how many standard deviations should be added to the mean
    -                   value of each protein measurement across replicates,
    -                   broadening the confidence interval. (Optional,
    -                   default = 1)
    -
    - Output:
    -   protData        structure with (filtered) proteome data
    -                   uniprotIDs  cell arrray with Uniprot IDs matching
    -                               protData.abundances
    -                   abundances  matrix of proteomics data, where each
    -                               column contains mean abundances per
    -                               condition
    -
    - Usage:
    -   protData = loadProtData(replPerCond, protDataFile, filterData, modelAdapter, minVal, maxRSD, maxMissing, cutLowest, addStdevs)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function protData = loadProtData(replPerCond, protDataFile, filterData, modelAdapter, minVal, maxRSD, maxMissing, cutLowest, addStdevs)
    -0002 % loadProtData
    -0003 %   Function that loads absolute proteomics data (in mg/gDCW) and returns
    -0004 %   mean values across replicates for each condition in the data file. By
    -0005 %   default it also filters the data by various criteria, to remove
    -0006 %   uncertain data (see input parameters).
    -0007 %
    -0008 % Input:
    -0009 %   replPerCond     vector with number of replicates for each condition in
    -0010 %                   the dataset. Example: [3, 2] if first conditions has
    -0011 %                   triplicates and second condition has duplicates.
    -0012 %   protDataFile    path to file with proteomics data, where protein levels
    -0013 %                   are in mg/gDCW (Optional, default reads
    -0014 %                   data/proteomics.tsv as specified in modelAdapter)
    -0015 %                   Alternatively, protDataFile can be a protData structure
    -0016 %                   that was previously made by loadProtdata.
    -0017 %   filterData      logical whether abundances should be filtered. If
    -0018 %                   false, minVal, maxRSD, maxMissing and addStdevs are not
    -0019 %                   considered. (Optional, default true)
    -0020 %   modelAdapter    a loaded model adapter (Optional, will otherwise use
    -0021 %                   the default model adapter)
    -0022 %   minVal          threshold of mean protein measurement per condition.
    -0023 %                   (Optional, default = 0)
    -0024 %   maxRSD          maximum relative standard per condition. (Optional,
    -0025 %                   default = 1)
    -0026 %   maxMissing      ratio of replicates for which a protein level might be
    -0027 %                   missing. (Optional, default = 1/3 (or 1/2 if number of
    -0028 %                   replicates = 2))
    -0029 %                   If conditions have different number of replicates (as
    -0030 %                   indicated in replPerCond), maxMissing can also be a
    -0031 %                   vector of the same length as replPerCond, with
    -0032 %                   individual maxMissing parameters for each replicate.
    -0033 %   cutLowest       percentage of lowest mean values per condition to be
    -0034 %                   discared (not considering NaN values). (Optional, default 5)
    -0035 %   addStdevs       how many standard deviations should be added to the mean
    -0036 %                   value of each protein measurement across replicates,
    -0037 %                   broadening the confidence interval. (Optional,
    -0038 %                   default = 1)
    -0039 %
    -0040 % Output:
    -0041 %   protData        structure with (filtered) proteome data
    -0042 %                   uniprotIDs  cell arrray with Uniprot IDs matching
    -0043 %                               protData.abundances
    -0044 %                   abundances  matrix of proteomics data, where each
    -0045 %                               column contains mean abundances per
    -0046 %                               condition
    -0047 %
    -0048 % Usage:
    -0049 %   protData = loadProtData(replPerCond, protDataFile, filterData, modelAdapter, minVal, maxRSD, maxMissing, cutLowest, addStdevs)
    -0050 
    -0051 if nargin < 8 || isempty(addStdevs)
    -0052     addStdevs = 1;
    -0053 end
    -0054 
    -0055 if nargin < 7 || isempty(maxMissing)
    -0056     maxMissing = 2/3;
    -0057 end
    -0058 
    -0059 if nargin < 6 || isempty(maxRSD)
    -0060     maxRSD = 1;
    -0061 end
    -0062 
    -0063 if nargin < 5 || isempty(minVal)
    -0064     minVal = 0;
    -0065 end
    -0066 
    -0067 if nargin < 4 || isempty(modelAdapter)
    -0068     modelAdapter = ModelAdapterManager.getDefault();
    -0069     if isempty(modelAdapter)
    -0070         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0071     end
    -0072 end
    -0073 params = modelAdapter.getParameters();
    -0074 
    -0075 if nargin < 3 || isempty(filterData)
    -0076     filterData = true;
    -0077 end
    -0078 
    -0079 if nargin < 2 || isempty(protDataFile)
    -0080     protDataFile = fullfile(params.path,'data','proteomics.tsv');
    -0081 end
    -0082 
    -0083 format = '%s';
    -0084 for i=1:sum(replPerCond)
    -0085     format = [format ' %f'];
    -0086 end
    -0087 if ~isstruct(protDataFile)
    -0088     checkFileExistence(protDataFile);
    -0089     fID         = fopen(protDataFile);
    -0090     protDataRaw = textscan(fID,format,'Delimiter','\t','HeaderLines',1,'TreatAsEmpty',{'NA','na','NaN','#VALUE!'});
    -0091     uniprotIDs  = protDataRaw{1};
    -0092     abundances  = cell2mat(protDataRaw(2:end));
    -0093     fclose(fID);
    -0094 else
    -0095     uniprotIDs  = protDataFile.uniprotIDs;
    -0096     abundances  = protDataFile.abundances;
    -0097 end
    -0098 
    -0099 %Remove entriew without ID
    -0100 remData = cellfun(@isempty,uniprotIDs);
    -0101 uniprotIDs(remData,:) = [];
    -0102 abundances(remData,:) = [];
    -0103 m                     = size(abundances,1);
    -0104 filtAbund             = nan(m,numel(replPerCond));
    -0105 
    -0106 if filterData
    -0107     for i=1:numel(replPerCond)
    -0108         condAbund    = abundances(:,1:replPerCond(i));
    -0109         if i<numel(replPerCond)
    -0110             abundances   = abundances(:,replPerCond(i)+1:end);
    -0111         end
    -0112         % First filter maxMissing
    -0113         if size(condAbund,2) > 1
    -0114             if numel(maxMissing)>1
    -0115                 maxMisRepl = maxMissing(i);
    -0116             else
    -0117                 maxMisRepl = maxMissing;
    -0118             end
    -0119             remData = sum(condAbund>0,2)<maxMisRepl*size(condAbund,2);
    -0120             condAbund(remData,:) = nan;
    -0121         end
    -0122         % Filter by RSD
    -0123         remData = (std(condAbund,0,2,'omitnan')./mean(condAbund,2,'omitnan'))>maxRSD;
    -0124         condAbund(remData) = nan;
    -0125         % Add stdevs
    -0126         condAbund = mean(condAbund,2,'omitnan')+(addStdevs*std(condAbund,0,2,'omitnan'));
    -0127         % Filter by minVal
    -0128         remData = mean(condAbund,2,'omitnan')<minVal;
    -0129         condAbund(remData) = nan;
    -0130         % Remove bottom 5%
    -0131         numData  = find(~isnan(condAbund));
    -0132         [~,sortData] = sort(condAbund);
    -0133         lowCutoff = floor(numel(numData)*0.05);
    -0134         condAbund(sortData(1:lowCutoff)) = nan;
    -0135         % Combine conditions
    -0136         filtAbund(:,i) = condAbund;
    -0137     end
    -0138 else
    -0139     for i=1:numel(replPerCond)
    -0140         condAbund    = abundances(:,1:replPerCond(i));
    -0141         if i<numel(replPerCond)
    -0142             abundances = abundances(:,replPerCond(i)+1:end);
    -0143         end
    -0144         filtAbund(:,i) = mean(condAbund,2,'omitnan');
    -0145     end
    -0146 end
    -0147 notAllNan = logical(sum(~isnan(filtAbund),2));
    -0148 protData.abundances = filtAbund(notAllNan,:);
    -0149 protData.uniprotIDs = uniprotIDs(notAllNan);
    -0150 end
    -0151
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/mapRxnsToConv.html b/doc/src/geckomat/utilities/mapRxnsToConv.html deleted file mode 100644 index f897fcd1..00000000 --- a/doc/src/geckomat/utilities/mapRxnsToConv.html +++ /dev/null @@ -1,122 +0,0 @@ - - - - Description of mapRxnsToConv - - - - - - - - - -
    Home > src > geckomat > utilities > mapRxnsToConv.m
    - - - -

    mapRxnsToConv -

    - -

    PURPOSE ^

    -
    mapRxnsToConv
    - -

    SYNOPSIS ^

    -
    function [mappedFlux, enzUsageFlux, usageEnz] = mapRxnsToConv(ecModel, model, fluxVect)
    - -

    DESCRIPTION ^

    -
     mapRxnsToConv
    -   A vector (or matrix) of fluxes is mapped to the reactions in the
    -   conventional starting model that was used to construct the ecModel. It
    -   is essential that the provided conventional model is indeed the model
    -   that was used to initate ecModel reconstruction.
    -
    - Input:
    -   ecModel         an ecModel in GECKO 3 format (with ecModel.ec structure),
    -                   that was used to obtain fluxVect
    -   model           the starting model for ecModel, to which the reactions
    -                   should be mapped
    -   fluxVect        vector or matrix of flux values, matching ecModel.rxns
    -
    - Output:
    -   mappedFlux      vector or matrix of flux values, matching model.rxns
    -   enzUsageFlux    vector or matrix of flux values from enzyme usage
    -                   reactions, as these are absent from mappedFlux
    -   usageEnz        cell array with protein IDs, matching enzUsageFlux
    -
    - Usage:
    -   [mappedFlux, enzUsageFlux, usageEnz] = mapRxnsToConv(ecModel, model, fluxVect)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: - - - - - -

    SOURCE CODE ^

    -
    0001 function [mappedFlux, enzUsageFlux, usageEnz] = mapRxnsToConv(ecModel, model, fluxVect)
    -0002 % mapRxnsToConv
    -0003 %   A vector (or matrix) of fluxes is mapped to the reactions in the
    -0004 %   conventional starting model that was used to construct the ecModel. It
    -0005 %   is essential that the provided conventional model is indeed the model
    -0006 %   that was used to initate ecModel reconstruction.
    -0007 %
    -0008 % Input:
    -0009 %   ecModel         an ecModel in GECKO 3 format (with ecModel.ec structure),
    -0010 %                   that was used to obtain fluxVect
    -0011 %   model           the starting model for ecModel, to which the reactions
    -0012 %                   should be mapped
    -0013 %   fluxVect        vector or matrix of flux values, matching ecModel.rxns
    -0014 %
    -0015 % Output:
    -0016 %   mappedFlux      vector or matrix of flux values, matching model.rxns
    -0017 %   enzUsageFlux    vector or matrix of flux values from enzyme usage
    -0018 %                   reactions, as these are absent from mappedFlux
    -0019 %   usageEnz        cell array with protein IDs, matching enzUsageFlux
    -0020 %
    -0021 % Usage:
    -0022 %   [mappedFlux, enzUsageFlux, usageEnz] = mapRxnsToConv(ecModel, model, fluxVect)
    -0023 
    -0024 if isempty(fluxVect)
    -0025     error('No or empty flux vector provided')
    -0026 end
    -0027 
    -0028 fluxes = fluxVect;
    -0029 rxnIDs = ecModel.rxns;
    -0030 
    -0031 % Invert flux of _REV reactions
    -0032 revRxns = endsWith(rxnIDs,'_REV') | contains(rxnIDs,'_REV_EXP_');
    -0033 fluxes(revRxns,:) = -fluxes(revRxns,:);
    -0034 rxnIDs(revRxns) = replace(rxnIDs(revRxns),'_REV','');
    -0035 % Remove _EXP_. suffixes
    -0036 rxnIDs = regexprep(rxnIDs,'_EXP_\d+','');
    -0037 
    -0038 % Map and sum fluxes to converted reaction IDs
    -0039 [rxnIDmap, convRxnID] = findgroups(rxnIDs);
    -0040 newVect = splitapply(@(x){sum(x,1)}, fluxes, rxnIDmap);
    -0041 newVect = cell2mat(newVect);
    -0042 
    -0043 % Place in same order as in original model
    -0044 [mapCheck,origIdx] = ismember(model.rxns,convRxnID);
    -0045 if ~all(mapCheck)
    -0046     error('Not all reactions from model.rxns can be found in the ecModel. Are you sure that ecModel is derived from model?')
    -0047 end
    -0048 mappedFlux=newVect(origIdx,:);
    -0049 
    -0050 % Separately report enzyme usages
    -0051 usageEnz = startsWith(ecModel.rxns,{'usage_prot_','prot_pool_exchange'});
    -0052 enzUsageFlux = fluxVect(usageEnz,:);
    -0053 usageEnz = regexprep(ecModel.rxns(usageEnz),'usage_prot_','');
    -0054 usageEnz = regexprep(usageEnz,'prot_pool_exchange','pool');
    -0055 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/plotEcFVA.html b/doc/src/geckomat/utilities/plotEcFVA.html deleted file mode 100644 index 31b5b0d8..00000000 --- a/doc/src/geckomat/utilities/plotEcFVA.html +++ /dev/null @@ -1,140 +0,0 @@ - - - - Description of plotEcFVA - - - - - - - - - -
    Home > src > geckomat > utilities > plotEcFVA.m
    - - - -

    plotEcFVA -

    - -

    PURPOSE ^

    -
    plotEcFVA
    - -

    SYNOPSIS ^

    -
    function plotEcFVA(minFlux, maxFlux)
    - -

    DESCRIPTION ^

    -
     plotEcFVA
    -   Plots cumulative distribution functions of ecFVA results from one or
    -   model ecModel(s) and/or GEM(s).
    -
    - Input:
    -   minFlux     vector of minimum flux values, coming from ecFVA. If
    -               multiple ecModels/GEMs are to be visualized, then each
    -               column represents a separate model.
    -   maxFlux     vector of maximum flux values, matching minFlux.
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - -

    SUBFUNCTIONS ^

    - - -

    SOURCE CODE ^

    -
    0001 function plotEcFVA(minFlux, maxFlux)
    -0002 % plotEcFVA
    -0003 %   Plots cumulative distribution functions of ecFVA results from one or
    -0004 %   model ecModel(s) and/or GEM(s).
    -0005 %
    -0006 % Input:
    -0007 %   minFlux     vector of minimum flux values, coming from ecFVA. If
    -0008 %               multiple ecModels/GEMs are to be visualized, then each
    -0009 %               column represents a separate model.
    -0010 %   maxFlux     vector of maximum flux values, matching minFlux.
    -0011 
    -0012 numMods = size(minFlux,2);
    -0013 fluxRanges = cell(3,1);
    -0014 % Ignore zero flux reactions
    -0015 for i=1:numMods
    -0016     zeroFlux = abs(minFlux(:,i)) < 1e-10 & abs(maxFlux(:,i)) < 1e-10;
    -0017     minFlux(zeroFlux,i) = NaN;
    -0018     maxFlux(zeroFlux,i) = NaN;
    -0019     fluxRange = maxFlux(:,i) - minFlux(:,i);
    -0020     fluxRange(isnan(fluxRange)) = [];
    -0021     fluxRanges{i} = fluxRange;
    -0022 end
    -0023 
    -0024 % Plot all together
    -0025 hold on
    -0026 legendText = cell(1,numel(numMods));
    -0027 for i=1:numMods
    -0028     fluxRange = fluxRanges{i};
    -0029     cdfplot(fluxRange)
    -0030     legendText{i} = (['Model #' num2str(i) ' (median: ' num2str(median(fluxRange,'omitnan')) ')']);
    -0031 end
    -0032 set(gca, 'XScale', 'log', 'Xlim', [1e-7 1e4])
    -0033 set(findall(gca, 'Type', 'Line'), 'LineWidth', 2)
    -0034 legend(legendText,  'Location','northwest')
    -0035 title('Flux variability (cumulative distribution)');
    -0036 xlabel('Variability range (mmol/gDCWh)');
    -0037 ylabel('Cumulative distribution');
    -0038 hold off
    -0039 end
    -0040 
    -0041 function cdfplot(X)
    -0042 % cdfplot(X)
    -0043 % displays a plot of the Empirical Cumulative Distribution Function
    -0044 % (CDF) of the input array X in the current figure. The empirical
    -0045 % CDF y=F(x) is defined as the proportion of X values less than or equal to x.
    -0046 % If input X is a matrix, then cdfplot(X) parses it to the vector and
    -0047 % displays CDF of all values.
    -0048 %
    -0049 % EXAMPLE:
    -0050 % figure;
    -0051 % cdfplot(randn(1,100));
    -0052 % hold on;
    -0053 % cdfplot(-log(1-rand(1,100)));
    -0054 % cdfplot(sqrt(randn(1,100).^2 + randn(1,100).^2))
    -0055 % legend('Normal(0,1) CDF', 'Exponential(1) CDF', 'Rayleigh(1) CDF', 4)
    -0056 
    -0057 % Version 1.0
    -0058 % Alex Podgaetsky, September 2003
    -0059 % alex@wavion.co.il
    -0060 %
    -0061 % Revisions:
    -0062 %       Version 1.0 -   initial version
    -0063 
    -0064 tmp = sort(reshape(X,prod(size(X)),1));
    -0065 Xplot = reshape([tmp tmp].',2*length(tmp),1);
    -0066 
    -0067 tmp = [1:length(X)].'/length(X);
    -0068 Yplot = reshape([tmp tmp].',2*length(tmp),1);
    -0069 Yplot = [0; Yplot(1:(end-1))];
    -0070 
    -0071 figure(gcf);
    -0072 hp = plot(Xplot, Yplot);
    -0073 
    -0074 ColOrd = get(gca, 'ColorOrder'); 
    -0075 ord = mod(length(get(gca,'Children')), size(ColOrd,1)); 
    -0076 set(hp, 'Color', ColOrd((ord==0) + (ord>0)*ord, :));
    -0077 if ~ishold
    -0078      xlabel('X', 'FontWeight','b','FontSize',12);
    -0079      ylabel('F(X)', 'FontWeight','b','FontSize',12);
    -0080      title('Empirical CDF', 'FontWeight','b','FontSize',12);
    -0081      grid on;
    -0082 end
    -0083 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/reportEnzymeUsage.html b/doc/src/geckomat/utilities/reportEnzymeUsage.html deleted file mode 100644 index a9d017c7..00000000 --- a/doc/src/geckomat/utilities/reportEnzymeUsage.html +++ /dev/null @@ -1,225 +0,0 @@ - - - - Description of reportEnzymeUsage - - - - - - - - - -
    Home > src > geckomat > utilities > reportEnzymeUsage.m
    - - - -

    reportEnzymeUsage -

    - -

    PURPOSE ^

    -
    reportEnzymeUsage
    - -

    SYNOPSIS ^

    -
    function usageReport = reportEnzymeUsage(ecModel, usageData, highCapUsage, topAbsUsage)
    - -

    DESCRIPTION ^

    -
     reportEnzymeUsage
    -   Summarizes the results from enzymeUsage.
    -
    -  Input:
    -   ecModel         a GECKO3 ecModel
    -   usageData       output from enzymeUsage
    -   highCapUsage    minimum ratio of enzyme capacity usage to be considered
    -                   as high usage (Optional, default 0.9, refering to a 
    -                   minimum of 90% capacity usage)
    -   topAbsUsage     number of top enzymes with highest absolute usage
    -                   (Optional, default 10, returning the top 10 enzymes
    -                   with highest absolute usage. With Inf or 0, all enzymes
    -                   are returned)
    -
    -  Output:
    -   usageReport     table with summary information
    -
    - Usage:
    -   usageReport = reportEnzymeUsage(ecModel, usageData, highCapUsage)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function usageReport = reportEnzymeUsage(ecModel, usageData, highCapUsage, topAbsUsage)
    -0002 % reportEnzymeUsage
    -0003 %   Summarizes the results from enzymeUsage.
    -0004 %
    -0005 %  Input:
    -0006 %   ecModel         a GECKO3 ecModel
    -0007 %   usageData       output from enzymeUsage
    -0008 %   highCapUsage    minimum ratio of enzyme capacity usage to be considered
    -0009 %                   as high usage (Optional, default 0.9, refering to a
    -0010 %                   minimum of 90% capacity usage)
    -0011 %   topAbsUsage     number of top enzymes with highest absolute usage
    -0012 %                   (Optional, default 10, returning the top 10 enzymes
    -0013 %                   with highest absolute usage. With Inf or 0, all enzymes
    -0014 %                   are returned)
    -0015 %
    -0016 %  Output:
    -0017 %   usageReport     table with summary information
    -0018 %
    -0019 % Usage:
    -0020 %   usageReport = reportEnzymeUsage(ecModel, usageData, highCapUsage)
    -0021 
    -0022 if nargin < 3 || isempty(highCapUsage)
    -0023     highCapUsage = 0.9;
    -0024 end
    -0025 if nargin < 4 || isempty(topAbsUsage)
    -0026     topAbsUsage = 10;
    -0027 end
    -0028 
    -0029 usageReport = {};
    -0030 
    -0031 % Highest capacity usage
    -0032 highUsageProt = find(usageData.capUsage > highCapUsage);
    -0033 highEnzyme    = usageData.protID(highUsageProt);
    -0034 [~,enzIdx]    = ismember(highEnzyme,ecModel.ec.enzymes);
    -0035 geneIDs       = ecModel.ec.genes(enzIdx);
    -0036 
    -0037 highUsage.protID     = {};
    -0038 highUsage.geneID     = {};
    -0039 highUsage.absUsage   = [];
    -0040 highUsage.capUsage   = [];
    -0041 highUsage.kcat       = [];
    -0042 highUsage.source     = {};
    -0043 highUsage.rxnID      = {};
    -0044 highUsage.rxnNames   = {};
    -0045 highUsage.grRules    = {};
    -0046 
    -0047 for i=1:numel(enzIdx)
    -0048     [rxns, kcat, idx, rxnNames, grRules] = getReactionsFromEnzyme(ecModel,ecModel.ec.enzymes(enzIdx(i)));
    -0049     % See if all reactions carried flux
    -0050     [~,rIdx] = ismember(rxns,ecModel.rxns);
    -0051     carriedFlux = usageData.fluxes(rIdx) > 1e-7;
    -0052     if isscalar(find(carriedFlux))
    -0053         highUsage.protID(end+1,1)      = highEnzyme(i);
    -0054         highUsage.geneID(end+1,1)      = geneIDs(i);
    -0055         highUsage.absUsage(end+1,1)    = usageData.absUsage(enzIdx(i));
    -0056         highUsage.capUsage(end+1,1)    = usageData.capUsage(enzIdx(i));
    -0057         highUsage.kcat(end+1,1)        = kcat(carriedFlux);
    -0058         highUsage.source(end+1,1)      = ecModel.ec.source(idx(carriedFlux));
    -0059         highUsage.rxnID(end+1,1)       = rxns(carriedFlux);
    -0060         highUsage.rxnNames(end+1,1)    = rxnNames(carriedFlux);
    -0061         highUsage.grRules(end+1,1)     = grRules(carriedFlux);
    -0062     else
    -0063         % Add one entry for combined usage
    -0064         highUsage.protID(end+1,1)      = highEnzyme(i);
    -0065         highUsage.geneID(end+1,1)      = geneIDs(i);
    -0066         highUsage.absUsage(end+1,1)    = usageData.absUsage(enzIdx(i));
    -0067         highUsage.capUsage(end+1,1)    = usageData.capUsage(enzIdx(i));
    -0068         highUsage.kcat(end+1,1)        = nan;
    -0069         highUsage.source{end+1,1}      = '===';
    -0070         highUsage.rxnID{end+1,1}       = '===';
    -0071         highUsage.rxnNames{end+1,1}    = 'involved in multiple rxns, usage combined, individual rxns below';
    -0072         highUsage.grRules{end+1,1}     = '===';
    -0073         % Recalculate reaction-specific usage
    -0074 
    -0075         rIdx = rIdx(carriedFlux);
    -0076         enzFlux = usageData.fluxes(rIdx);
    -0077         enzMet = strcat('prot_',highEnzyme{i});
    -0078         [~, enzEcIdx] = ismember(enzMet,ecModel.mets);
    -0079         indAbsUse = full(transpose(-ecModel.S(enzEcIdx,rIdx)).*enzFlux);
    -0080         indCapUse = (indAbsUse /sum(indAbsUse)) * usageData.capUsage(enzIdx(i));
    -0081 
    -0082         rxnNumber = length(rIdx);
    -0083         highUsage.protID(end+1:end+rxnNumber,1)      = highEnzyme(i);
    -0084         highUsage.geneID(end+1:end+rxnNumber,1)      = geneIDs(i);
    -0085         highUsage.absUsage(end+1:end+rxnNumber,1)    = indAbsUse;
    -0086         highUsage.capUsage(end+1:end+rxnNumber,1)    = indCapUse;
    -0087         highUsage.kcat(end+1:end+rxnNumber,1)        = kcat(carriedFlux);
    -0088         highUsage.source(end+1:end+rxnNumber,1)      = ecModel.ec.source(idx(carriedFlux));
    -0089         highUsage.rxnID(end+1:end+rxnNumber,1)       = rxns(carriedFlux);
    -0090         highUsage.rxnNames(end+1:end+rxnNumber,1)    = rxnNames(carriedFlux);
    -0091         highUsage.grRules(end+1:end+rxnNumber,1)     = grRules(carriedFlux);
    -0092     end    
    -0093 end
    -0094 
    -0095 usageReport.highCapUsage = struct2table(highUsage);
    -0096 
    -0097 % Highest absolute usage
    -0098 [~,topUse]          = sort(usageData.absUsage,'descend');
    -0099 topEnzyme           = usageData.protID(topUse(1:topAbsUsage));
    -0100 [~,b]       = ismember(topEnzyme,ecModel.ec.enzymes);
    -0101 geneIDs     = ecModel.ec.genes(b);
    -0102 topUsage.protID     = {};
    -0103 topUsage.geneID     = {};
    -0104 topUsage.absUsage   = [];
    -0105 topUsage.percUsage  = [];
    -0106 topUsage.kcat       = [];
    -0107 topUsage.source     = {};
    -0108 topUsage.rxnID      = {};
    -0109 topUsage.rxnNames   = {};
    -0110 topUsage.grRules    = {};
    -0111 
    -0112 protPool = -ecModel.lb(strcmp(ecModel.rxns,'prot_pool_exchange'));
    -0113 
    -0114 for i=1:numel(topEnzyme)
    -0115     [rxns, kcat, idx, rxnNames, grRules] = getReactionsFromEnzyme(ecModel,topEnzyme{i});
    -0116     % See if all reactions carried flux
    -0117     [~,rIdx] = ismember(rxns,ecModel.rxns);
    -0118     carriedFlux = usageData.fluxes(rIdx) > 1e-7;
    -0119     if isscalar(find(carriedFlux))
    -0120         topUsage.protID(end+1,1)      = topEnzyme(i);
    -0121         topUsage.geneID(end+1,1)      = geneIDs(i);
    -0122         topUsage.absUsage(end+1,1)    = usageData.absUsage(topUse(i));
    -0123         topUsage.percUsage(end+1,1)   = topUsage.absUsage(end,1)/protPool*100;
    -0124         topUsage.kcat(end+1,1)        = kcat(carriedFlux);
    -0125         topUsage.source(end+1,1)      = ecModel.ec.source(idx(carriedFlux));
    -0126         topUsage.rxnID(end+1,1)       = rxns(carriedFlux);
    -0127         topUsage.rxnNames(end+1,1)    = rxnNames(carriedFlux);
    -0128         topUsage.grRules(end+1,1)     = grRules(carriedFlux);
    -0129     else
    -0130         % Add one entry for combined usage
    -0131         topUsage.protID(end+1,1)      = topEnzyme(i);
    -0132         topUsage.geneID(end+1,1)      = geneIDs(i);
    -0133         topUsage.absUsage(end+1,1)    = usageData.absUsage(topUse(i));
    -0134         topUsage.percUsage(end+1,1)   = topUsage.absUsage(end,1)/protPool*100;
    -0135         topUsage.kcat(end+1,1)        = nan;
    -0136         topUsage.source{end+1,1}      = '===';
    -0137         topUsage.rxnID{end+1,1}       = '===';
    -0138         topUsage.rxnNames{end+1,1}    = 'involved in multiple rxns, usage combined, individual rxns below';
    -0139         topUsage.grRules{end+1,1}     = '===';
    -0140         % Recalculate reaction-specific usage
    -0141         rIdx = rIdx(carriedFlux);
    -0142         enzFlux = usageData.fluxes(rIdx);
    -0143         enzMet = strcat('prot_',topEnzyme{i});
    -0144         [~, enzIdx] = ismember(enzMet,ecModel.mets);
    -0145         indUse = full(transpose(-ecModel.S(enzIdx,rIdx)).*enzFlux);
    -0146         rxnNumber = length(rIdx);
    -0147         topUsage.protID(end+1:end+rxnNumber,1)      = topEnzyme(i);
    -0148         topUsage.geneID(end+1:end+rxnNumber,1)      = geneIDs(i);
    -0149         topUsage.absUsage(end+1:end+rxnNumber,1)    = indUse;
    -0150         topUsage.percUsage(end+1:end+rxnNumber,1)   = topUsage.absUsage(end-(rxnNumber-1):end,1)/protPool*100;
    -0151         topUsage.kcat(end+1:end+rxnNumber,1)        = kcat(carriedFlux);
    -0152         topUsage.source(end+1:end+rxnNumber,1)      = ecModel.ec.source(idx(carriedFlux));
    -0153         topUsage.rxnID(end+1:end+rxnNumber,1)       = rxns(carriedFlux);
    -0154         topUsage.rxnNames(end+1:end+rxnNumber,1)    = rxnNames(carriedFlux);
    -0155         topUsage.grRules(end+1:end+rxnNumber,1)     = grRules(carriedFlux);
    -0156     end
    -0157 end
    -0158 usageReport.topAbsUsage     = struct2table(topUsage);
    -0159 usageReport.totalUsageFlux  = protPool;
    -0160 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/saveEcModel.html b/doc/src/geckomat/utilities/saveEcModel.html deleted file mode 100644 index 304a2d2f..00000000 --- a/doc/src/geckomat/utilities/saveEcModel.html +++ /dev/null @@ -1,137 +0,0 @@ - - - - Description of saveEcModel - - - - - - - - - -
    Home > src > geckomat > utilities > saveEcModel.m
    - - - -

    saveEcModel -

    - -

    PURPOSE ^

    -
    saveECmodel
    - -

    SYNOPSIS ^

    -
    function saveEcModel(ecModel,filename,modelAdapter)
    - -

    DESCRIPTION ^

    -
     saveECmodel
    -   Saves the ecModel in either YAML format (= default and preferred, as
    -   all ecModel content is reserved) and/or SBML format (= more widely
    -   compatible with other constraint-based modelling tools, can be used for
    -   running simulations like FBA etc., but this model cannot be loaded back
    -   into MATLAB for applying further GECKO functions, as model.ec is lost).
    -
    -   The ecModel is saved to the ecModel-specific models/ subfolder. For
    -   saving to other locations, writeYAMLmodel or exportModel are more
    -   suitable.
    -
    - Input:
    -   ecModel         an ecModel in GECKO 3 format (with ecModel.ec structure)
    -   filename        ending with either .yml or .xml, specifying if the
    -                   ecModel should be saved in YAML or SBML file format. If
    -                   no file extension is given, the ecModel will be saved
    -                   in YAML format. If no filename is given, 'ecModel.yml'
    -                   is used.
    -   modelAdapter    a loaded model adapter, from where the model folder is
    -                   read (Optional, will otherwise use the default model adapter).
    -
    - Usage:
    -   saveECmodel(ecModel,filename,modelAdapter)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: -
      -
    -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function saveEcModel(ecModel,filename,modelAdapter)
    -0002 % saveECmodel
    -0003 %   Saves the ecModel in either YAML format (= default and preferred, as
    -0004 %   all ecModel content is reserved) and/or SBML format (= more widely
    -0005 %   compatible with other constraint-based modelling tools, can be used for
    -0006 %   running simulations like FBA etc., but this model cannot be loaded back
    -0007 %   into MATLAB for applying further GECKO functions, as model.ec is lost).
    -0008 %
    -0009 %   The ecModel is saved to the ecModel-specific models/ subfolder. For
    -0010 %   saving to other locations, writeYAMLmodel or exportModel are more
    -0011 %   suitable.
    -0012 %
    -0013 % Input:
    -0014 %   ecModel         an ecModel in GECKO 3 format (with ecModel.ec structure)
    -0015 %   filename        ending with either .yml or .xml, specifying if the
    -0016 %                   ecModel should be saved in YAML or SBML file format. If
    -0017 %                   no file extension is given, the ecModel will be saved
    -0018 %                   in YAML format. If no filename is given, 'ecModel.yml'
    -0019 %                   is used.
    -0020 %   modelAdapter    a loaded model adapter, from where the model folder is
    -0021 %                   read (Optional, will otherwise use the default model adapter).
    -0022 %
    -0023 % Usage:
    -0024 %   saveECmodel(ecModel,filename,modelAdapter)
    -0025 
    -0026 
    -0027 if nargin < 3 || isempty(modelAdapter)
    -0028     modelAdapter = ModelAdapterManager.getDefault();
    -0029     if isempty(modelAdapter)
    -0030         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    -0031     end
    -0032 end
    -0033 params = modelAdapter.getParameters();
    -0034 if nargin < 2 || isempty(filename)
    -0035     filename = 'ecModel';
    -0036 end
    -0037 filename = fullfile(params.path,'models',filename);
    -0038 
    -0039 ecModel.description = ['Enzyme-constrained model of ' ecModel.id];
    -0040 
    -0041 switch filename(end-3:end)
    -0042     case {'.xml','sbml'}
    -0043         exportModel(ecModel, filename);
    -0044         %Convert notation "e-005" to "e-05 " in stoich. coeffs. to avoid
    -0045         %inconsistencies between Windows and MAC:
    -0046         copyfile(filename,'backup.xml')
    -0047         fin  = fopen('backup.xml', 'r');
    -0048         fout = fopen(filename, 'w');
    -0049         still_reading = true;
    -0050         while still_reading
    -0051             inline = fgets(fin);
    -0052             if ~ischar(inline)
    -0053                 still_reading = false;
    -0054             else
    -0055                 if ~isempty(regexp(inline,'-00[0-9]','once'))
    -0056                     inline = strrep(inline,'-00','-0');
    -0057                 elseif ~isempty(regexp(inline,'-01[0-9]','once'))
    -0058                     inline = strrep(inline,'-01','-1');
    -0059                 end
    -0060                 fwrite(fout, inline);
    -0061             end
    -0062         end
    -0063         fclose('all');
    -0064         delete('backup.xml');
    -0065     otherwise % Assume YAML
    -0066         writeYAMLmodel(ecModel,filename);
    -0067 end
    -0068 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/startGECKOproject.html b/doc/src/geckomat/utilities/startGECKOproject.html deleted file mode 100644 index 190d5b0d..00000000 --- a/doc/src/geckomat/utilities/startGECKOproject.html +++ /dev/null @@ -1,120 +0,0 @@ - - - - Description of startGECKOproject - - - - - - - - - -
    Home > src > geckomat > utilities > startGECKOproject.m
    - - - -

    startGECKOproject -

    - -

    PURPOSE ^

    -
    startGECKOproject
    - -

    SYNOPSIS ^

    -
    function startGECKOproject(name, path)
    - -

    DESCRIPTION ^

    -
     startGECKOproject
    -   Function that create a basic project structure for GECKO. If a project
    -   with the same name exits, the project will not be created
    -
    - Input:
    -   name               an name for the folder struture used in GECKO. Also
    -                      creates a basic adapter class, which must be manually
    -                      adjusted. If not defined, a dialog box will appear.
    -   path               a path where to create the folder. If not defined, a
    -                      dialog box will appear.
    -
    - Usage:
    -   startGECKOproject(name, path)
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: - -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function startGECKOproject(name, path)
    -0002 % startGECKOproject
    -0003 %   Function that create a basic project structure for GECKO. If a project
    -0004 %   with the same name exits, the project will not be created
    -0005 %
    -0006 % Input:
    -0007 %   name               an name for the folder struture used in GECKO. Also
    -0008 %                      creates a basic adapter class, which must be manually
    -0009 %                      adjusted. If not defined, a dialog box will appear.
    -0010 %   path               a path where to create the folder. If not defined, a
    -0011 %                      dialog box will appear.
    -0012 %
    -0013 % Usage:
    -0014 %   startGECKOproject(name, path)
    -0015 
    -0016 if nargin < 1 || isempty(name)
    -0017     prompt = {'Please provide a project name (e.g. ecYeastGEM)'};
    -0018     dlgtitle = 'Project name';
    -0019     dims = [1 100];
    -0020     definput = {'ecModelGEM'};
    -0021     opts.Interpreter = 'tex';
    -0022     name = inputdlg(prompt,dlgtitle,dims,definput,opts);
    -0023     name = char(name);
    -0024 end
    -0025 
    -0026 if nargin < 2 || isempty(path)
    -0027     path = uigetdir('Project Folder path');
    -0028 end
    -0029 
    -0030 fullPath = fullfile(path, name);
    -0031 % Validate if the project does not exits
    -0032 if ~exist(fullPath, 'dir')
    -0033     % Create the subfolder
    -0034     dir = {'code', 'data', 'models', 'output'};
    -0035     for i = 1:length(dir)
    -0036         status = mkdir(fullPath, dir{i});
    -0037         fid = fopen(fullfile(fullPath, dir{i}, '.keep'), 'w');
    -0038         fclose(fid);
    -0039     end
    -0040 
    -0041     % Read the template adapter class
    -0042     fid = fopen(fullfile(findGECKOroot, 'src', 'geckomat', ...
    -0043         'model_adapter', 'adapterTemplate.m'));
    -0044     f = fread(fid, '*char')';
    -0045     fclose(fid);
    -0046 
    -0047     % Replace key values
    -0048     f = strrep(f, 'KEY_CLASSNAME', [name 'Adapter']);
    -0049     f = strrep(f, 'KEY_PATH', path);
    -0050     f = strrep(f, 'KEY_NAME', name);
    -0051 
    -0052     % Save the class file
    -0053     filename = fullfile(path, name, [name 'Adapter.m']);
    -0054     fid = fopen(filename, 'w');
    -0055     fwrite(fid, f);
    -0056     fclose(fid);
    -0057 else
    -0058     printOrange('WARNING: A project with the same name exits at the same location. The project was not created.\n');
    -0059 end
    -0060 cd(fullPath)
    -0061 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/geckomat/utilities/updateGECKOdoc.html b/doc/src/geckomat/utilities/updateGECKOdoc.html deleted file mode 100644 index 52d4bb00..00000000 --- a/doc/src/geckomat/utilities/updateGECKOdoc.html +++ /dev/null @@ -1,88 +0,0 @@ - - - - Description of updateGECKOdoc - - - - - - - - - -
    Home > src > geckomat > utilities > updateGECKOdoc.m
    - - - -

    updateGECKOdoc -

    - -

    PURPOSE ^

    -
    updateGeckoDoc
    - -

    SYNOPSIS ^

    -
    function updateGECKOdoc()
    - -

    DESCRIPTION ^

    -
     updateGeckoDoc
    -    Updates HTML documentation files for all geckomat GECKO functions. Uses the
    -   m2html functions that are provided with RAVEN.
    -
    - Usage: updateGECKOdoc()
    - - -

    CROSS-REFERENCE INFORMATION ^

    -This function calls: - -This function is called by: -
      -
    - - - - -

    SOURCE CODE ^

    -
    0001 function updateGECKOdoc()
    -0002 % updateGeckoDoc
    -0003 %    Updates HTML documentation files for all geckomat GECKO functions. Uses the
    -0004 %   m2html functions that are provided with RAVEN.
    -0005 %
    -0006 % Usage: updateGECKOdoc()
    -0007 
    -0008 %Make sure that RAVEN-provided m2html is used
    -0009 ravenDir=findRAVENroot();
    -0010 path(fullfile(ravenDir,'software','m2html'),path);
    -0011 
    -0012 %Get the GECKO path
    -0013 geckoDir=findGECKOroot();
    -0014 
    -0015 %Remove old doc directory
    -0016 rmdir(fullfile(geckoDir,'doc'),'s');
    -0017 
    -0018 %Get a non-redundant list of GECKO subdirectories containing MATLAB
    -0019 %functions. Absolute paths are not compatible with M2HTML, so convert them
    -0020 %to the relative paths instead.
    -0021 geckoDirs=dir(fullfile(geckoDir,'src','geckomat','**/*.m'));
    -0022 geckoDirs=unique({geckoDirs.folder})';
    -0023 
    -0024 %Make relative path
    -0025 relStart = numel(geckoDir)+2;
    -0026 for i=1:numel(geckoDirs)
    -0027     geckoDirs{i,1} = geckoDirs{i,1}(relStart:end);
    -0028 end
    -0029 
    -0030 %Save the current working directory and go to RAVEN root directory
    -0031 originalDir=pwd;
    -0032 cd(geckoDir);
    -0033 %Generate HTML documentation files for RAVEN MATLAB functions
    -0034 m2html('mFiles',geckoDirs,'htmldir','doc');
    -0035 %Go back to the original working directory
    -0036 cd(originalDir);
    -0037 end
    -
    Generated by m2html © 2005
    - - \ No newline at end of file diff --git a/doc/src/get_enzyme_data/applyECcodes.html b/doc/src/get_enzyme_data/applyECcodes.html new file mode 100644 index 00000000..e6804063 --- /dev/null +++ b/doc/src/get_enzyme_data/applyECcodes.html @@ -0,0 +1,133 @@ + + + + Description of applyECcodes + + + + + + + + + +
    Home > src > get_enzyme_data > applyECcodes.m
    + + + +

    applyECcodes +

    + +

    PURPOSE ^

    +
    applyECcodes Copy EC numbers from ecModel.ec.eccodes to ecModel.eccodes.
    + +

    SYNOPSIS ^

    +
    function ecModel = applyECcodes(ecModel, varargin)
    + +

    DESCRIPTION ^

    +
     applyECcodes  Copy EC numbers from ecModel.ec.eccodes to ecModel.eccodes.
    +
    + Copies the EC numbers stored in the ecModel.ec structure across to the
    + top-level ecModel.eccodes field.
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + overwrite : logical
    +     whether existing (non-empty) ecModel.eccodes entries should be
    +     overwritten by a non-empty ecModel.ec.eccodes entry. Empty
    +     ecModel.eccodes entries are always overwritten if possible (default
    +     false). An empty ecModel.ec.eccodes source entry is never copied, so
    +     it can never erase an existing annotation.
    +
    + Returns
    + -------
    + ecModel : struct
    +     ecModel with populated model.eccodes.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     ecModel = applyECcodes(ecModel, true);
    +     ecModel = applyECcodes(ecModel, 'overwrite', true);
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function ecModel = applyECcodes(ecModel, varargin)
    +0002 % applyECcodes  Copy EC numbers from ecModel.ec.eccodes to ecModel.eccodes.
    +0003 %
    +0004 % Copies the EC numbers stored in the ecModel.ec structure across to the
    +0005 % top-level ecModel.eccodes field.
    +0006 %
    +0007 % Parameters
    +0008 % ----------
    +0009 % ecModel : struct
    +0010 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0011 %
    +0012 % Name-Value Arguments
    +0013 % --------------------
    +0014 % overwrite : logical
    +0015 %     whether existing (non-empty) ecModel.eccodes entries should be
    +0016 %     overwritten by a non-empty ecModel.ec.eccodes entry. Empty
    +0017 %     ecModel.eccodes entries are always overwritten if possible (default
    +0018 %     false). An empty ecModel.ec.eccodes source entry is never copied, so
    +0019 %     it can never erase an existing annotation.
    +0020 %
    +0021 % Returns
    +0022 % -------
    +0023 % ecModel : struct
    +0024 %     ecModel with populated model.eccodes.
    +0025 %
    +0026 % Examples
    +0027 % --------
    +0028 %     % optional arguments may be given positionally or as name-value pairs:
    +0029 %     ecModel = applyECcodes(ecModel, true);
    +0030 %     ecModel = applyECcodes(ecModel, 'overwrite', true);
    +0031 
    +0032 p = parseGECKOargs(varargin, { ...
    +0033     'overwrite', false});
    +0034 overwrite = p.overwrite;
    +0035 
    +0036 if ~isfield(ecModel.ec,'eccodes')
    +0037     error('ecModel.ec.eccodes does not exist')
    +0038 end
    +0039 
    +0040 [a,b] = ismember(ecModel.rxns,ecModel.ec.rxns);
    +0041 if ~isfield(ecModel,'eccodes')
    +0042     ecModel.eccodes = cell(numel(ecModel.rxns),1);
    +0043 end
    +0044 
    +0045 if overwrite
    +0046     % Never overwrite an existing eccodes entry with an empty source: an
    +0047     % unset ec.eccodes value means "no info to copy", not "clear the
    +0048     % annotation".
    +0049     nonEmptySource = false(size(a));
    +0050     nonEmptySource(a) = ~cellfun(@isempty, ecModel.ec.eccodes(b(a)));
    +0051     a = a & nonEmptySource;
    +0052     ecModel.eccodes(a) = ecModel.ec.eccodes(b(a));
    +0053 else % Only replace emptyEcCodes
    +0054     emptyEcCodes = cellfun(@isempty, ecModel.eccodes);
    +0055     a = a & emptyEcCodes;
    +0056     ecModel.eccodes(a) = ecModel.ec.eccodes(b(a));
    +0057 end
    +0058 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/get_enzyme_data/calculateMW.html b/doc/src/get_enzyme_data/calculateMW.html new file mode 100644 index 00000000..5726c557 --- /dev/null +++ b/doc/src/get_enzyme_data/calculateMW.html @@ -0,0 +1,148 @@ + + + + Description of calculateMW + + + + + + + + + +
    Home > src > get_enzyme_data > calculateMW.m
    + + + +

    calculateMW +

    + +

    PURPOSE ^

    +
    calculateMW Calculate the molecular weight of a protein.
    + +

    SYNOPSIS ^

    +
    function MW = calculateMW(sequence)
    + +

    DESCRIPTION ^

    +
     calculateMW  Calculate the molecular weight of a protein.
    +
    + Calculates the molecular weight of a protein from its amino acid sequence.
    + Matching is case-insensitive. Sequences with no recognized residue
    + (including an empty sequence) return NaN, rather than being mistaken for
    + an 18 Da protein.
    +
    + Parameters
    + ----------
    + sequence : char
    +     the amino acid sequence (can include extra things such as spaces or
    +     numbers, which are ignored).
    +
    + Returns
    + -------
    + MW : double
    +     the molecular weight in Da, or NaN if no residue was recognized.
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function MW = calculateMW(sequence)
    +0002 % calculateMW  Calculate the molecular weight of a protein.
    +0003 %
    +0004 % Calculates the molecular weight of a protein from its amino acid sequence.
    +0005 % Matching is case-insensitive. Sequences with no recognized residue
    +0006 % (including an empty sequence) return NaN, rather than being mistaken for
    +0007 % an 18 Da protein.
    +0008 %
    +0009 % Parameters
    +0010 % ----------
    +0011 % sequence : char
    +0012 %     the amino acid sequence (can include extra things such as spaces or
    +0013 %     numbers, which are ignored).
    +0014 %
    +0015 % Returns
    +0016 % -------
    +0017 % MW : double
    +0018 %     the molecular weight in Da, or NaN if no residue was recognized.
    +0019 
    +0020 % A    Alanine
    +0021 % B    Aspartic acid or Asparagine
    +0022 % C    Cysteine
    +0023 % D    Aspartic acid
    +0024 % E    Glutamic acid
    +0025 % F    Phenylalanine
    +0026 % G    Glycine
    +0027 % H    Histidine
    +0028 % I    Isoleucine
    +0029 % J    Leucine or Isoleucine
    +0030 % K    Lysine
    +0031 % L    Leucine
    +0032 % M    Methionine
    +0033 % N    Asparagine
    +0034 % O    Pyrrolysine
    +0035 % P    Proline
    +0036 % Q    Glutamine
    +0037 % R    Arginine
    +0038 % S    Serine
    +0039 % T    Threonine
    +0040 % U    Selenocysteine
    +0041 % V    Valine
    +0042 % W    Tryptophan
    +0043 % X    any
    +0044 % Y    Tyrosine
    +0045 % Z    Glutamic acid or Glutamine
    +0046 
    +0047 % The 20 standard residues, individually sourced.
    +0048 aa_codes = {'A','C','D','E','F','G','H','I','K','L','M','N','P','Q','R', ...
    +0049             'S','T','V','W','Y'};
    +0050 aa_MWs   = [71.08 103.14 115.09 129.11 147.17 57.05 137.14 113.16 128.17 ...
    +0051             113.16 131.20 114.10 97.12 128.13 156.19 87.08 101.10 99.13 ...
    +0052             186.21 163.17];
    +0053 
    +0054 % Ambiguous / non-standard codes, derived from the standard table above
    +0055 % rather than pre-rounded constants: B/Z average their two possible
    +0056 % residues, X averages across all 20 standard residues, J is Leu-or-Ile
    +0057 % (both 113.16, so either index gives the same value), O/U have no
    +0058 % standard-residue equivalent and keep their literature values.
    +0059 bMW = mean(aa_MWs(ismember(aa_codes,{'D','N'})));
    +0060 zMW = mean(aa_MWs(ismember(aa_codes,{'E','Q'})));
    +0061 xMW = mean(aa_MWs);
    +0062 jMW = aa_MWs(strcmp(aa_codes,'L'));
    +0063 
    +0064 allCodes = [aa_codes, {'B','J','O','U','X','Z'}];
    +0065 allMWs   = [aa_MWs, bMW, jMW, 255.31, 150.04, xMW, zMW];
    +0066 
    +0067 % Average mass of water (g/mol): the two H atoms and one OH that remain
    +0068 % after peptide bond condensation.
    +0069 waterMW = 18.01528;
    +0070 
    +0071 sequence = upper(sequence);
    +0072 MW = waterMW;
    +0073 nMatched = 0;
    +0074 for i = 1:length(allCodes)
    +0075     count = length(strfind(sequence,allCodes{i}));
    +0076     MW = MW + count*allMWs(i);
    +0077     nMatched = nMatched + count;
    +0078 end
    +0079 if nMatched == 0
    +0080     MW = NaN;
    +0081 end
    +0082 
    +0083 end
    +0084 
    +0085 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/get_enzyme_data/findECInDB.html b/doc/src/get_enzyme_data/findECInDB.html new file mode 100644 index 00000000..5db9a685 --- /dev/null +++ b/doc/src/get_enzyme_data/findECInDB.html @@ -0,0 +1,302 @@ + + + + Description of findECInDB + + + + + + + + + +
    Home > src > get_enzyme_data > findECInDB.m
    + + + +

    findECInDB +

    + +

    PURPOSE ^

    +
    findECInDB Look up EC numbers for a reaction's gene set in a UniProt or KEGG index.
    + +

    SYNOPSIS ^

    +
    function [EC,conflicts] = findECInDB(gene_set, DBecNum, DBMW, geneIndex, geneHashMap)
    + +

    DESCRIPTION ^

    +
     findECInDB  Look up EC numbers for a reaction's gene set in a UniProt or KEGG index.
    +
    + For each gene, finds its matching database entries and takes the EC number
    + of the lightest-weight matching protein when a single EC number applies to
    + that gene; genes with several distinct EC numbers among their matches are
    + also reported as conflicts (the first match is still used for EC). Genes
    + without an EC number are left out. When gene_set has more than one gene
    + (an enzyme complex), the numbers found for each gene are combined by
    + intersection where they share a match (a wildcard such as "1.1.1.-" matches
    + the specific codes of its prefix), otherwise by union. The EC set of every
    + gene set, one gene or a complex, is cleaned of a wildcard code such as
    + "1.1.1.-" when a more specific code of the same prefix ("1.1.1.4") is
    + present; only codes with four levels take part, and empty codes are removed.
    +
    + Parameters
    + ----------
    + gene_set : cell
    +     genes from a given metabolic reaction.
    + DBecNum : cell
    +     array of EC numbers.
    + DBMW : double
    +     array of molecular weights in Da.
    + geneIndex : cell
    +     as generated by getECfromDatabase.
    + geneHashMap : containers.Map
    +     as generated by getECfromDatabase.
    +
    + Returns
    + -------
    + EC : char
    +     EC numbers that apply to gene_set, each prefixed with "EC" and
    +     separated by ";" (e.g. "EC1.1.1.1;EC1.1.1.2").
    + conflicts : cell
    +     genes with multiple protein matches.
    +
    + Examples
    + --------
    +     [EC, conflicts] = findECInDB(gene_set, DBecNum, DBMW, geneIndex, geneHashMap);
    +
    + See also
    + --------
    + getECfromDatabase, getECstring
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • getECstring getECstring Build a single string of EC numbers for a protein.
    +This function is called by: +
      +
    • getECfromDatabase getECfromDatabase Populate model.ec.eccodes from UniProt and KEGG databases.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [EC,conflicts] = findECInDB(gene_set, DBecNum, DBMW, geneIndex, geneHashMap)
    +0002 % findECInDB  Look up EC numbers for a reaction's gene set in a UniProt or KEGG index.
    +0003 %
    +0004 % For each gene, finds its matching database entries and takes the EC number
    +0005 % of the lightest-weight matching protein when a single EC number applies to
    +0006 % that gene; genes with several distinct EC numbers among their matches are
    +0007 % also reported as conflicts (the first match is still used for EC). Genes
    +0008 % without an EC number are left out. When gene_set has more than one gene
    +0009 % (an enzyme complex), the numbers found for each gene are combined by
    +0010 % intersection where they share a match (a wildcard such as "1.1.1.-" matches
    +0011 % the specific codes of its prefix), otherwise by union. The EC set of every
    +0012 % gene set, one gene or a complex, is cleaned of a wildcard code such as
    +0013 % "1.1.1.-" when a more specific code of the same prefix ("1.1.1.4") is
    +0014 % present; only codes with four levels take part, and empty codes are removed.
    +0015 %
    +0016 % Parameters
    +0017 % ----------
    +0018 % gene_set : cell
    +0019 %     genes from a given metabolic reaction.
    +0020 % DBecNum : cell
    +0021 %     array of EC numbers.
    +0022 % DBMW : double
    +0023 %     array of molecular weights in Da.
    +0024 % geneIndex : cell
    +0025 %     as generated by getECfromDatabase.
    +0026 % geneHashMap : containers.Map
    +0027 %     as generated by getECfromDatabase.
    +0028 %
    +0029 % Returns
    +0030 % -------
    +0031 % EC : char
    +0032 %     EC numbers that apply to gene_set, each prefixed with "EC" and
    +0033 %     separated by ";" (e.g. "EC1.1.1.1;EC1.1.1.2").
    +0034 % conflicts : cell
    +0035 %     genes with multiple protein matches.
    +0036 %
    +0037 % Examples
    +0038 % --------
    +0039 %     [EC, conflicts] = findECInDB(gene_set, DBecNum, DBMW, geneIndex, geneHashMap);
    +0040 %
    +0041 % See also
    +0042 % --------
    +0043 % getECfromDatabase, getECstring
    +0044 
    +0045 %Preallocate function variables
    +0046 conflicts = cell(1,2);
    +0047 
    +0048 %Split the gene set and match each gene:
    +0049 %gene_set  = strsplit(grRule,' and '); %this string splitting together with getSimpleGeneSets takes 2.6 s, that is ok.
    +0050 EC_set    = cell(size(gene_set));
    +0051 
    +0052 %find index indices of all genes in one call
    +0053 
    +0054 %this loop is slow
    +0055 for j = 1:length(gene_set)
    +0056      gene = gene_set{j};
    +0057      matches = [];
    +0058      %Get the indexes for all of the proteins related to gene
    +0059      if isKey(geneHashMap,gene) %annoyingly, this seems to be needed
    +0060          matchInd = cell2mat(values(geneHashMap,gene_set(j)));
    +0061          matches = geneIndex{matchInd};
    +0062      end
    +0063      if ~isempty(matches)
    +0064         %Get the indexes of the matched protein(s) with non-empty EC#s
    +0065         nonEmpty = matches(~cellfun(@isempty,DBecNum(matches)));
    +0066         if ~isempty(nonEmpty)
    +0067             [geneECs,ia] = unique(DBecNum(nonEmpty),'stable');
    +0068             %For genes with multiple proteins associated to several
    +0069             %non-empty ecNumbers
    +0070             if length(geneECs)>1
    +0071                 indexes = nonEmpty(ia);
    +0072                 ecNum = DBecNum(indexes);
    +0073                 %Save first match
    +0074                 EC_set{j}  = getECstring(EC_set{j},ecNum{1});
    +0075                 %Save additional matches as potential conflicts
    +0076                 if ~ismember(gene,conflicts{1})
    +0077                     conflicts{1} = [conflicts{1}; {gene}];
    +0078                     conflicts{2} = [conflicts{2}; {indexes}]; 
    +0079                 end
    +0080             else
    +0081                 %If there is a single unique ec number for the matched
    +0082                 %protein(s), then choose the lightest protein
    +0083                 [~,minW]   = min(DBMW(nonEmpty));
    +0084                 matches    = nonEmpty(minW);
    +0085                 EC_set{j}  = getECstring(EC_set{j},DBecNum{matches});
    +0086             end
    +0087         end
    +0088     end
    +0089 
    +0090     if isempty(EC_set{j})
    +0091         EC_set{j} = '';
    +0092     end
    +0093 end
    +0094 
    +0095 %EC: Split the codes of each gene, leave out the genes without any, and
    +0096 %combine the rest (union and intersection only apply for complexes, i.e. more
    +0097 %than one gene with codes):
    +0098 tokens = cell(size(EC_set));
    +0099 for j = 1:length(EC_set)
    +0100     codes     = strsplit(EC_set{j},' ');
    +0101     tokens{j} = codes(~cellfun(@isempty,codes));
    +0102 end
    +0103 tokens = tokens(~cellfun(@isempty,tokens));
    +0104 if isempty(tokens)
    +0105     EC_set = {};
    +0106 elseif isscalar(tokens)
    +0107     EC_set = dropWildcardParents(tokens{1});
    +0108 else
    +0109     uni_EC = tokens{1};
    +0110     int_EC = tokens{1};
    +0111     for j = 2:length(tokens)
    +0112         uni_EC = dropWildcardParents([uni_EC tokens{j}]);
    +0113         int_EC = wildcardIntersection(int_EC,tokens{j});
    +0114     end
    +0115     %Use the intersection found, if any. If not, use the union:
    +0116     if isempty(int_EC)
    +0117         EC_set = uni_EC;
    +0118     else
    +0119         EC_set = int_EC;
    +0120     end
    +0121     EC_set = dropWildcardParents(EC_set);
    +0122 end
    +0123 
    +0124 %Add new codes as new possible isozymes and remove the initial "EC" text:
    +0125 
    +0126 for i = 1:length(EC_set)
    +0127    if ~isempty(EC_set{i}) 
    +0128        EC_set{i} = extractAfter(EC_set{i},2);%remove 2 first chars
    +0129    end
    +0130 end
    +0131 
    +0132 %EC_set = cellfun(@(x) extractAfter(x,2),EC_set,'UniformOutput',false);%remove 2 first chars
    +0133 if isempty(EC_set)
    +0134     EC = '';
    +0135 else
    +0136     EC = strjoin(EC_set,';');
    +0137 end
    +0138 
    +0139 
    +0140 %Delete repeated Uniprots (and the corresponding ECs):
    +0141 %EC(deleted)   = []; %Not sure if this needs to be done somehow, don't think so
    +0142 
    +0143 end
    +0144 
    +0145 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0146 function int_EC = wildcardIntersection(prev_EC,new_EC)
    +0147 %Finds the common elements between two cell arrays, if any. Also considers
    +0148 %wildcards (e.g. if 'EC1.1.1.1' is in one array and 'EC1.1.1.-' is in the
    +0149 %other one, then 'EC1.1.1.1' is added to the intersection). A pair adds its
    +0150 %code only when one code of the pair is the wildcard parent of the other, or
    +0151 %the two are equal four-level codes.
    +0152 int_EC = {};
    +0153 for i = 1:length(prev_EC)
    +0154     for j = 1:length(new_EC)
    +0155         survivors = dropWildcardParents({prev_EC{i} new_EC{j}});
    +0156         if length(survivors) == 1
    +0157             int_EC = [int_EC survivors];
    +0158         end
    +0159     end
    +0160 end
    +0161 end
    +0162 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0163 function int_EC = dropWildcardParents(EC)
    +0164 %Removes empty codes and every code that is a wildcard parent of another
    +0165 %code in the cell array (e.g. 'EC1.2.3.-' when 'EC1.2.3.4' is present). Only
    +0166 %codes with four levels are compared, so 'EC1.1.1' is neither a parent nor a
    +0167 %child of 'EC1.1.1.4'. Equal codes collapse to the first.
    +0168 EC = EC(~cellfun(@isempty,EC) & ~strcmp(EC,'EC'));
    +0169 keep = true(1,numel(EC));
    +0170 for i = 1:numel(EC)
    +0171     if ~keep(i)
    +0172         continue;
    +0173     end
    +0174     for j = i+1:numel(EC)
    +0175         if ~keep(j)
    +0176             continue;
    +0177         end
    +0178         iInJ = subsumes(EC{i},EC{j});
    +0179         jInI = subsumes(EC{j},EC{i});
    +0180         if iInJ && jInI
    +0181             keep(j) = false;
    +0182         elseif iInJ
    +0183             keep(i) = false;
    +0184             break;
    +0185         elseif jInI
    +0186             keep(j) = false;
    +0187         end
    +0188     end
    +0189 end
    +0190 int_EC = EC(keep);
    +0191 end
    +0192 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0193 function tf = subsumes(general,specific)
    +0194 %True if the code general is equal to or a wildcard parent of the code
    +0195 %specific; both carry the "EC" prefix and need four levels.
    +0196 general  = strsplit(extractAfter(general,2),'.');
    +0197 specific = strsplit(extractAfter(specific,2),'.');
    +0198 tf = false;
    +0199 if numel(general) ~= 4 || numel(specific) ~= 4
    +0200     return;
    +0201 end
    +0202 for k = 1:4
    +0203     if strcmp(general{k},'-')
    +0204         tf = true;
    +0205         return;
    +0206     end
    +0207     if strcmp(specific{k},'-') || ~strcmp(general{k},specific{k})
    +0208         return;
    +0209     end
    +0210 end
    +0211 tf = true;
    +0212 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/get_enzyme_data/getECfromDatabase.html b/doc/src/get_enzyme_data/getECfromDatabase.html new file mode 100644 index 00000000..13327274 --- /dev/null +++ b/doc/src/get_enzyme_data/getECfromDatabase.html @@ -0,0 +1,297 @@ + + + + Description of getECfromDatabase + + + + + + + + + +
    Home > src > get_enzyme_data > getECfromDatabase.m
    + + + +

    getECfromDatabase +

    + +

    PURPOSE ^

    +
    getECfromDatabase Populate model.ec.eccodes from UniProt and KEGG databases.
    + +

    SYNOPSIS ^

    +
    function model = getECfromDatabase(model, varargin)
    + +

    DESCRIPTION ^

    +
     getECfromDatabase  Populate model.ec.eccodes from UniProt and KEGG databases.
    +
    + Populates the model.ec.eccodes field with enzyme codes that are extracted
    + from UniProt and KEGG databases, as assigned to the proteins that catalyze
    + the specific reactions.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + ecRxns : logical
    +     of length model.ec.rxns that specifies which model.ec.eccodes entries
    +     should be queried. Existing values in model.ec.eccodes will be wiped.
    +     Entries that are indicated by false will be kept and not modified by
    +     this function (by default all model.ec.eccodes entries are populated
    +     by this function).
    + action : char
    +     response action if multiple proteins with different EC numbers are
    +     found for a given gene in a metabolic reaction (default 'display'):
    +
    +     - 'display' displays all found multiplicities.
    +     - 'ignore' ignore multiplicities and use the protein with the lowest
    +       index in the database.
    +     - 'add' adds all the multiple proteins as isozymes for the given
    +       reaction.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + model : struct
    +     ecModel with populated model.ec.eccodes.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     model = getECfromDatabase(model, ecRxns, action, modelAdapter);
    +     model = getECfromDatabase(model, 'action', 'ignore');
    +
    + See also
    + --------
    + getECfromGEM, findECInDB, loadDatabases
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • findECInDB findECInDB Look up EC numbers for a reaction's gene set in a UniProt or KEGG index.
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function model = getECfromDatabase(model, varargin)
    +0002 % getECfromDatabase  Populate model.ec.eccodes from UniProt and KEGG databases.
    +0003 %
    +0004 % Populates the model.ec.eccodes field with enzyme codes that are extracted
    +0005 % from UniProt and KEGG databases, as assigned to the proteins that catalyze
    +0006 % the specific reactions.
    +0007 %
    +0008 % Parameters
    +0009 % ----------
    +0010 % model : struct
    +0011 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0012 %
    +0013 % Name-Value Arguments
    +0014 % --------------------
    +0015 % ecRxns : logical
    +0016 %     of length model.ec.rxns that specifies which model.ec.eccodes entries
    +0017 %     should be queried. Existing values in model.ec.eccodes will be wiped.
    +0018 %     Entries that are indicated by false will be kept and not modified by
    +0019 %     this function (by default all model.ec.eccodes entries are populated
    +0020 %     by this function).
    +0021 % action : char
    +0022 %     response action if multiple proteins with different EC numbers are
    +0023 %     found for a given gene in a metabolic reaction (default 'display'):
    +0024 %
    +0025 %     - 'display' displays all found multiplicities.
    +0026 %     - 'ignore' ignore multiplicities and use the protein with the lowest
    +0027 %       index in the database.
    +0028 %     - 'add' adds all the multiple proteins as isozymes for the given
    +0029 %       reaction.
    +0030 % modelAdapter : ModelAdapter
    +0031 %     a loaded model adapter (default: the current default model adapter).
    +0032 %
    +0033 % Returns
    +0034 % -------
    +0035 % model : struct
    +0036 %     ecModel with populated model.ec.eccodes.
    +0037 %
    +0038 % Examples
    +0039 % --------
    +0040 %     % optional arguments may be given positionally or as name-value pairs:
    +0041 %     model = getECfromDatabase(model, ecRxns, action, modelAdapter);
    +0042 %     model = getECfromDatabase(model, 'action', 'ignore');
    +0043 %
    +0044 % See also
    +0045 % --------
    +0046 % getECfromGEM, findECInDB, loadDatabases
    +0047 
    +0048 p = parseGECKOargs(varargin, { ...
    +0049     'ecRxns',       []; ...
    +0050     'action',       'display'; ...
    +0051     'modelAdapter', []});
    +0052 ecRxns       = p.ecRxns;
    +0053 action       = p.action;
    +0054 modelAdapter = p.modelAdapter;
    +0055 
    +0056 if isempty(modelAdapter)
    +0057     modelAdapter = ModelAdapterManager.getDefault();
    +0058     if isempty(modelAdapter)
    +0059         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0060     end
    +0061 end
    +0062 params = modelAdapter.getParameters();
    +0063 
    +0064 rxnEnzMat = model.ec.rxnEnzMat;
    +0065 genes = modelAdapter.getUniprotCompatibleGenes(model.ec.genes);
    +0066 
    +0067 data    = loadDatabases('both', modelAdapter);
    +0068 uniprot = data.uniprot;
    +0069 kegg    = data.kegg;
    +0070 
    +0071 modelGenes = modelAdapter.getUniprotIDsFromTable(model.genes);
    +0072 DBgenesUniprot  = data.uniprot.genes;
    +0073 if ~isequal(modelGenes,model.genes)
    +0074     [Lia,Locb] = ismember(modelGenes,uniprot.ID);
    +0075     DBgenesUniprot(Locb(Lia)) = model.genes(Lia);
    +0076     keepEntry = unique(Locb(Lia));
    +0077     DBgenesUniprot = DBgenesUniprot(keepEntry);
    +0078 else
    +0079     keepEntry = true(numel(DBgenesUniprot),1);
    +0080 end
    +0081 DBecNumUniprot  = data.uniprot.eccodes(keepEntry);
    +0082 DBMWUniprot     = data.uniprot.MW(keepEntry);
    +0083 %Build an index from gene to prot for faster processing later
    +0084 [geneIndexUniprot,geneHashMapUniprot] = hashGeneToProt(DBgenesUniprot);
    +0085 
    +0086 if ~isempty(kegg)
    +0087     DBgenesKEGG     = data.kegg.genes;
    +0088     DBecNumKEGG     = data.kegg.eccodes;
    +0089     DBMWKEGG        = data.kegg.MW;
    +0090     [geneIndexKEGG,geneHashMapKEGG]       = hashGeneToProt(DBgenesKEGG);
    +0091 end
    +0092 n = size(rxnEnzMat,1);
    +0093 
    +0094 eccodes   = cell(n,1);
    +0095 eccodes(:)= {''};
    +0096 conflicts = cell(1,4);
    +0097 
    +0098 rxnEnzMat = logical(rxnEnzMat);
    +0099 PB = progressReport(n, 'Assigning EC numbers from database');
    +0100 for i = 1:n
    +0101     PB.count;
    +0102     gns = genes(rxnEnzMat(i,:).');
    +0103     if ~isempty(gns)
    +0104         %Find match in Uniprot:
    +0105         [new_EC,multGenes] = findECInDB(gns,DBecNumUniprot,DBMWUniprot,geneIndexUniprot,geneHashMapUniprot);
    +0106         if ~isempty(new_EC)
    +0107             DBase    = 'uniprot';
    +0108             if ~isempty(multGenes{1})
    +0109                 multGenes{3} = DBase;
    +0110             end
    +0111         end
    +0112         if ~isempty(kegg) && (isempty(new_EC) || endsWith(new_EC,'-'))
    +0113             %Find match in KEGG
    +0114             [new_EC_kegg,multGenes] = findECInDB(gns,DBecNumKEGG,DBMWKEGG,geneIndexKEGG,geneHashMapKEGG);
    +0115             if ~isempty(new_EC_kegg)
    +0116                 DBase    = 'kegg';
    +0117                 if ~isempty(multGenes{1})
    +0118                     multGenes{3} = DBase;
    +0119                 end
    +0120                 new_EC=new_EC_kegg;
    +0121             end
    +0122         end
    +0123         eccodes{i} = new_EC;
    +0124 
    +0125         if ~isempty(multGenes{1})
    +0126             %Rxn index
    +0127             conflicts{1} = [conflicts{1};i];
    +0128             %Gene IDs
    +0129             conflicts{2} = [conflicts{2};multGenes{1}];
    +0130             %Indexes in DB
    +0131             conflicts{3} = [conflicts{3};multGenes{2}];
    +0132             %DB name
    +0133             conflicts{4} = [conflicts{4};{multGenes{3}}];
    +0134 
    +0135             %{ I don't understand the purpose of this, let's skip it for now
    +0136             %if strcmpi(action,'add')
    +0137             %    if strcmpi(DBase,'swissprot')
    +0138             %        [uni,EC,MW,Genes] = addMultipleMatches(uni,EC,MW,Genes,multGenes,swissprot);
    +0139             %    elseif strcmpi(DBase,'KEGG')
    +0140             %        [uni,EC,MW,Genes] = addMultipleMatches(uni,EC,MW,Genes,multGenes,kegg);
    +0141             %    end
    +0142             %end
    +0143             %}
    +0144         end
    +0145     end
    +0146 end
    +0147 
    +0148 %Display error message with the multiple gene-protein matches found
    +0149 if strcmpi(action,'display') && ~isempty(conflicts{1})
    +0150     displayErrorMessage(conflicts,uniprot,kegg)
    +0151 end
    +0152 
    +0153 if isempty(ecRxns) || all(ecRxns)
    +0154     model.ec.eccodes = eccodes;
    +0155 else
    +0156     if ~isfield(model.ec,'eccodes')
    +0157         model.ec.eccodes(1:numel(model.ec.rxns),1) = {''};
    +0158     end
    +0159     %Probably faster to subset with ecRxns in the beginning of the script,
    +0160     %but this was at the moment simpler to implement.
    +0161     model.ec.eccodes(ecRxns) = eccodes(ecRxns);
    +0162 end
    +0163 
    +0164 function displayErrorMessage(conflicts,uniprot,kegg)
    +0165 STR = ['\n ' num2str(length(conflicts{1})) ' genes with multiple associated proteins were found, please'];
    +0166 STR = [STR, ' revise case by case in the uniprot and kegg files:\n\n'];
    +0167 for i=1:length(conflicts{1})
    +0168     if strcmpi(conflicts{4}{i},'uniprot')
    +0169         DB = uniprot.ID;
    +0170     else
    +0171         DB = kegg.uniprot;
    +0172     end
    +0173     proteins = DB(conflicts{3}{i});
    +0174     STR = [STR, '- gene: ' conflicts{2}{i} '  Proteins: ' strjoin(proteins) '\n'];
    +0175 end
    +0176 STR = [STR, '\nIf a wrongly annotated case was found then call the '];
    +0177 STR = [STR, 'getECfromDatabase.m function again with the option action'];
    +0178 STR = [STR, '= ignore\n\n'];
    +0179 STR = [STR, 'If the conflicting proteins are desired to be kept as isozymes'];
    +0180 STR = [STR, ' then call the getECfromDatabase.m function'];
    +0181 STR = [STR, ' again with the option action = add\n'];
    +0182 error(sprintf(STR))
    +0183 end
    +0184 
    +0185 function [geneIndex,geneHashMap]=hashGeneToProt(proteinDB)
    +0186 
    +0187 [x,y] = size(proteinDB);
    +0188 genesForIndex = reshape(proteinDB, x*y, 1);
    +0189 genesForIndex = genesForIndex(~cellfun(@isempty, genesForIndex));
    +0190 genesForIndex = unique(genesForIndex);
    +0191 geneIndex = cell(length(genesForIndex),1);
    +0192 geneHashMap = containers.Map(genesForIndex,1:length(genesForIndex));
    +0193 protIndices = 1:length(proteinDB(:,1));
    +0194 for i = 1:y
    +0195     tmp1 = proteinDB(:,i);
    +0196     sel = ~cellfun(@isempty, tmp1);
    +0197     indices = cell2mat(values(geneHashMap,tmp1(sel)));
    +0198     protIndicesSel = protIndices(sel);
    +0199     for j = 1:length(indices)
    +0200         geneIndex{indices(j)} = [geneIndex{indices(j)};protIndicesSel(j)];
    +0201     end
    +0202 end
    +0203 end
    +0204 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/get_enzyme_data/getECfromGEM.html b/doc/src/get_enzyme_data/getECfromGEM.html new file mode 100644 index 00000000..f19a1369 --- /dev/null +++ b/doc/src/get_enzyme_data/getECfromGEM.html @@ -0,0 +1,179 @@ + + + + Description of getECfromGEM + + + + + + + + + +
    Home > src > get_enzyme_data > getECfromGEM.m
    + + + +

    getECfromGEM +

    + +

    PURPOSE ^

    +
    getECfromGEM Populate model.ec.eccodes from the model.eccodes field.
    + +

    SYNOPSIS ^

    +
    function [model, invalidEC, invalidECpos] = getECfromGEM(model, varargin)
    + +

    DESCRIPTION ^

    +
     getECfromGEM  Populate model.ec.eccodes from the model.eccodes field.
    +
    + Uses the model.eccodes to populate the model.ec.eccodes field. EC numbers
    + must be formatted as four numbers separated by periods, possibly with
    + trailing wildcards; incorrectly formatted EC numbers are skipped.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + ecRxns : logical
    +     of length model.ec.rxns that specifies for which reactions the
    +     existing model.ec.eccodes entry should be kept and not modified by
    +     this function (by default all model.ec.eccodes entries are populated
    +     by this function).
    +
    + Returns
    + -------
    + model : struct
    +     ecModel with populated model.ec.eccodes.
    + invalidEC : cell
    +     incorrectly formatted EC numbers.
    + invalidECpos : double
    +     position of invalidEC in model.eccodes.
    +
    + Notes
    + -----
    + Valid EC numbers are e.g. 1.2.3.4 or 1.2.3.-, while invalid EC numbers are
    + 1.2.3 or 1_2_3_4. Multiple EC numbers are separated by ; for instance
    + 1.2.3.4;1.2.3.5 not 1.2.3.4|1.2.3.5.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     [model, invalidEC, invalidECpos] = getECfromGEM(model, ecRxns);
    +     [model, invalidEC, invalidECpos] = getECfromGEM(model, 'ecRxns', ecRxns);
    +
    + See also
    + --------
    + getECfromDatabase, applyECcodes
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function [model, invalidEC, invalidECpos] = getECfromGEM(model, varargin)
    +0002 % getECfromGEM  Populate model.ec.eccodes from the model.eccodes field.
    +0003 %
    +0004 % Uses the model.eccodes to populate the model.ec.eccodes field. EC numbers
    +0005 % must be formatted as four numbers separated by periods, possibly with
    +0006 % trailing wildcards; incorrectly formatted EC numbers are skipped.
    +0007 %
    +0008 % Parameters
    +0009 % ----------
    +0010 % model : struct
    +0011 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0012 %
    +0013 % Name-Value Arguments
    +0014 % --------------------
    +0015 % ecRxns : logical
    +0016 %     of length model.ec.rxns that specifies for which reactions the
    +0017 %     existing model.ec.eccodes entry should be kept and not modified by
    +0018 %     this function (by default all model.ec.eccodes entries are populated
    +0019 %     by this function).
    +0020 %
    +0021 % Returns
    +0022 % -------
    +0023 % model : struct
    +0024 %     ecModel with populated model.ec.eccodes.
    +0025 % invalidEC : cell
    +0026 %     incorrectly formatted EC numbers.
    +0027 % invalidECpos : double
    +0028 %     position of invalidEC in model.eccodes.
    +0029 %
    +0030 % Notes
    +0031 % -----
    +0032 % Valid EC numbers are e.g. 1.2.3.4 or 1.2.3.-, while invalid EC numbers are
    +0033 % 1.2.3 or 1_2_3_4. Multiple EC numbers are separated by ; for instance
    +0034 % 1.2.3.4;1.2.3.5 not 1.2.3.4|1.2.3.5.
    +0035 %
    +0036 % Examples
    +0037 % --------
    +0038 %     % optional arguments may be given positionally or as name-value pairs:
    +0039 %     [model, invalidEC, invalidECpos] = getECfromGEM(model, ecRxns);
    +0040 %     [model, invalidEC, invalidECpos] = getECfromGEM(model, 'ecRxns', ecRxns);
    +0041 %
    +0042 % See also
    +0043 % --------
    +0044 % getECfromDatabase, applyECcodes
    +0045 
    +0046 p = parseGECKOargs(varargin, { ...
    +0047     'ecRxns', []});
    +0048 ecRxns = p.ecRxns;
    +0049 
    +0050 if ~isfield(model,'eccodes')
    +0051     error('The model has no model.eccodes field.')
    +0052 end
    +0053 
    +0054 %Need to remove the prefix of GECKO light rxn names in the ec structure
    +0055 if ~model.ec.geckoLight
    +0056     rxnNames = model.ec.rxns;
    +0057 else
    +0058     rxnNames = extractAfter(model.ec.rxns, 4);
    +0059 end
    +0060 
    +0061 [~,rxnIdxs] = ismember(rxnNames,model.rxns);
    +0062 
    +0063 % Check if eccodes are valid. Each of the four dot-separated components must
    +0064 % be either a run of digits or the wildcard '-'; \w (the previous class) also
    +0065 % matches letters and underscores, so malformed codes such as '1.1.1.n12' or
    +0066 % '1_2_3_4' were incorrectly accepted.
    +0067 eccodes = model.eccodes;
    +0068 invalidEC = regexprep(eccodes,'(\d+\.(\d+|-)\.(\d+|-)\.(\d+|-))(;\d+\.(\d+|-)\.(\d+|-)\.(\d+|-))*(.*)','$3');
    +0069 invalidEC = ~cellfun(@isempty,invalidEC);
    +0070 invalidECpos = find(invalidEC);
    +0071 if any(invalidECpos)
    +0072     invalidEC = model.eccodes(invalidEC);
    +0073     if nargout<2
    +0074         fprintf('Skipped incorrectly formatted EC numbers, rerun getECfromGEM with all outputs to get a list.\n')
    +0075     else
    +0076         fprintf('Skipped incorrectly formatted EC numbers.\n')
    +0077     end
    +0078     eccodes(invalidECpos)={''};
    +0079 else
    +0080     invalidEC = [];
    +0081 end
    +0082 if isempty(ecRxns) || all(ecRxns)
    +0083     model.ec.eccodes = eccodes(rxnIdxs);
    +0084 else
    +0085     if ~isfield(model.ec,'eccodes')
    +0086         model.ec.eccodes(1:numel(model.ec.rxns),1) = {''};
    +0087     end
    +0088     model.ec.eccodes(ecRxns) = eccodes(rxnIdxs(ecRxns));
    +0089 end
    +0090 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/get_enzyme_data/getECstring.html b/doc/src/get_enzyme_data/getECstring.html new file mode 100644 index 00000000..e5fc1e4f --- /dev/null +++ b/doc/src/get_enzyme_data/getECstring.html @@ -0,0 +1,110 @@ + + + + Description of getECstring + + + + + + + + + +
    Home > src > get_enzyme_data > getECstring.m
    + + + +

    getECstring +

    + +

    PURPOSE ^

    +
    getECstring Build a single string of EC numbers for a protein.
    + +

    SYNOPSIS ^

    +
    function EC_set = getECstring(EC_set,ecNumbers)
    + +

    DESCRIPTION ^

    +
     getECstring  Build a single string of EC numbers for a protein.
    +
    + Provides a single string with all the EC numbers associated to a given
    + protein, according to the following format:
    + "ECX.X.X.X ECX.X.X.X ECX.X.X.X".
    +
    + Parameters
    + ----------
    + EC_set : char
    +     existing EC string to which the EC numbers are appended.
    + ecNumbers : char
    +     EC numbers associated to the protein, separated by white space and/or
    +     semicolons.
    +
    + Returns
    + -------
    + EC_set : char
    +     a single string with all the EC numbers, each prefixed with "EC".
    +
    + Examples
    + --------
    +     EC_set = getECstring(EC_set, ecNumbers);
    +
    + See also
    + --------
    + findECInDB
    +In case of several ec numbers for the same protein
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • findECInDB findECInDB Look up EC numbers for a reaction's gene set in a UniProt or KEGG index.
    + + + + +

    SOURCE CODE ^

    +
    0001 function EC_set = getECstring(EC_set,ecNumbers)
    +0002 % getECstring  Build a single string of EC numbers for a protein.
    +0003 %
    +0004 % Provides a single string with all the EC numbers associated to a given
    +0005 % protein, according to the following format:
    +0006 % "ECX.X.X.X ECX.X.X.X ECX.X.X.X".
    +0007 %
    +0008 % Parameters
    +0009 % ----------
    +0010 % EC_set : char
    +0011 %     existing EC string to which the EC numbers are appended.
    +0012 % ecNumbers : char
    +0013 %     EC numbers associated to the protein, separated by white space and/or
    +0014 %     semicolons.
    +0015 %
    +0016 % Returns
    +0017 % -------
    +0018 % EC_set : char
    +0019 %     a single string with all the EC numbers, each prefixed with "EC".
    +0020 %
    +0021 % Examples
    +0022 % --------
    +0023 %     EC_set = getECstring(EC_set, ecNumbers);
    +0024 %
    +0025 % See also
    +0026 % --------
    +0027 % findECInDB
    +0028 %In case of several ec numbers for the same protein
    +0029 new_EC_set = regexp(strtrim(ecNumbers),'[;\s]+','split');
    +0030 new_EC_set = new_EC_set(~cellfun(@isempty,new_EC_set));
    +0031 for l = 1:length(new_EC_set)
    +0032     EC_set = [EC_set 'EC' new_EC_set{l}];
    +0033     if l<length(new_EC_set)
    +0034         EC_set = [EC_set ' '];
    +0035     end
    +0036 end
    +0037 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/get_enzyme_data/index.html b/doc/src/get_enzyme_data/index.html new file mode 100644 index 00000000..c4681c7f --- /dev/null +++ b/doc/src/get_enzyme_data/index.html @@ -0,0 +1,29 @@ + + + + Index for Directory src/get_enzyme_data + + + + + + + + + + +
    < Master indexIndex for src/get_enzyme_data >
    + +

    Index for src/get_enzyme_data

    + +

    Matlab files in this directory:

    + +
     applyECcodesapplyECcodes Copy EC numbers from ecModel.ec.eccodes to ecModel.eccodes.
     calculateMWcalculateMW Calculate the molecular weight of a protein.
     findECInDBfindECInDB Look up EC numbers for a reaction's gene set in a UniProt or KEGG index.
     getECfromDatabasegetECfromDatabase Populate model.ec.eccodes from UniProt and KEGG databases.
     getECfromGEMgetECfromGEM Populate model.ec.eccodes from the model.eccodes field.
     getECstringgetECstring Build a single string of EC numbers for a protein.
    + + + + +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/io/index.html b/doc/src/io/index.html new file mode 100644 index 00000000..17b25321 --- /dev/null +++ b/doc/src/io/index.html @@ -0,0 +1,29 @@ + + + + Index for Directory src/io + + + + + + + + + + +
    < Master indexIndex for src/io >
    + +

    Index for src/io

    + +

    Matlab files in this directory:

    + +
     loadConventionalGEMloadConventionalGEM Load the conventional GEM (non-ecModel).
     loadEcModelloadEcModel Load the ecModel that matches the modelAdapter.
     loadFluxDataloadFluxData Load total protein measurements and exchange flux data.
     loadProtDataloadProtData Load absolute proteomics data and average over replicates.
     saveEcModelsaveEcModel Save an ecModel in YAML and/or SBML format.
    + + + + +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/io/loadConventionalGEM.html b/doc/src/io/loadConventionalGEM.html new file mode 100644 index 00000000..697eb2fd --- /dev/null +++ b/doc/src/io/loadConventionalGEM.html @@ -0,0 +1,136 @@ + + + + Description of loadConventionalGEM + + + + + + + + + +
    Home > src > io > loadConventionalGEM.m
    + + + +

    loadConventionalGEM +

    + +

    PURPOSE ^

    +
    loadConventionalGEM Load the conventional GEM (non-ecModel).
    + +

    SYNOPSIS ^

    +
    function model = loadConventionalGEM(varargin)
    + +

    DESCRIPTION ^

    +
     loadConventionalGEM  Load the conventional GEM (non-ecModel).
    +
    + Loads the conventional GEM (non-ecModel) from the location specified in
    + the modelAdapter. By default, it looks in the models/ subdirectory of the
    + param.path specified in the modelAdapter. When loading conventional GEMs
    + from other locations, one can directly use importModel.
    +
    + Name-Value Arguments
    + --------------------
    + filename : char
    +     name of the model file, without extension, located in the models/
    +     subfolder of param.path as specified in the modelAdapter; it is
    +     loaded as SBML (.xml) (default: the value specified as param.convGEM
    +     in the modelAdapter, which may instead point to a YAML file).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter, from where the model folder is read (default:
    +     the current default model adapter).
    +
    + Returns
    + -------
    + model : struct
    +     model in RAVEN format.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     model = loadConventionalGEM(filename, modelAdapter);
    +     model = loadConventionalGEM('filename', filename);
    +
    + See also
    + --------
    + loadEcModel
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function model = loadConventionalGEM(varargin)
    +0002 % loadConventionalGEM  Load the conventional GEM (non-ecModel).
    +0003 %
    +0004 % Loads the conventional GEM (non-ecModel) from the location specified in
    +0005 % the modelAdapter. By default, it looks in the models/ subdirectory of the
    +0006 % param.path specified in the modelAdapter. When loading conventional GEMs
    +0007 % from other locations, one can directly use importModel.
    +0008 %
    +0009 % Name-Value Arguments
    +0010 % --------------------
    +0011 % filename : char
    +0012 %     name of the model file, without extension, located in the models/
    +0013 %     subfolder of param.path as specified in the modelAdapter; it is
    +0014 %     loaded as SBML (.xml) (default: the value specified as param.convGEM
    +0015 %     in the modelAdapter, which may instead point to a YAML file).
    +0016 % modelAdapter : ModelAdapter
    +0017 %     a loaded model adapter, from where the model folder is read (default:
    +0018 %     the current default model adapter).
    +0019 %
    +0020 % Returns
    +0021 % -------
    +0022 % model : struct
    +0023 %     model in RAVEN format.
    +0024 %
    +0025 % Examples
    +0026 % --------
    +0027 %     % optional arguments may be given positionally or as name-value pairs:
    +0028 %     model = loadConventionalGEM(filename, modelAdapter);
    +0029 %     model = loadConventionalGEM('filename', filename);
    +0030 %
    +0031 % See also
    +0032 % --------
    +0033 % loadEcModel
    +0034 
    +0035 p = parseGECKOargs(varargin, { ...
    +0036     'filename',     []; ...
    +0037     'modelAdapter', []});
    +0038 filename     = p.filename;
    +0039 modelAdapter = p.modelAdapter;
    +0040 
    +0041 if isempty(modelAdapter)
    +0042     modelAdapter = ModelAdapterManager.getDefault();
    +0043     if isempty(modelAdapter)
    +0044         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0045     end
    +0046 end
    +0047 params = modelAdapter.getParameters();
    +0048 if isempty(filename)
    +0049     filename = params.convGEM;
    +0050 else
    +0051     filename = fullfile(params.path,'models',[filename, '.xml'])
    +0052 end
    +0053 
    +0054 if endsWith(filename,'.xml')
    +0055     model = importModel(filename);
    +0056 elseif endsWith(filename,'.yml')
    +0057     model = readYAMLmodel(filename);
    +0058 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/io/loadEcModel.html b/doc/src/io/loadEcModel.html new file mode 100644 index 00000000..3ada7b2e --- /dev/null +++ b/doc/src/io/loadEcModel.html @@ -0,0 +1,170 @@ + + + + Description of loadEcModel + + + + + + + + + +
    Home > src > io > loadEcModel.m
    + + + +

    loadEcModel +

    + +

    PURPOSE ^

    +
    loadEcModel Load the ecModel that matches the modelAdapter.
    + +

    SYNOPSIS ^

    +
    function model = loadEcModel(varargin)
    + +

    DESCRIPTION ^

    +
     loadEcModel  Load the ecModel that matches the modelAdapter.
    +
    + Loads the ecModel that matches the modelAdapter. By default, it loads the
    + models/ecModel.yml in the directory specified as param.path in the
    + modelAdapter. Alternative files in the same folder can be loaded by
    + providing the appropriate filename. If loading models from other
    + locations, one can directly use readYAMLmodel.
    +
    + An ecModel whose protein usage and pool reactions run in the GECKO 3
    + direction is upgraded in the loaded model with upgradeEcModel, with a
    + warning. An ecModel format (gecko_format in the file's metaData, see
    + saveEcModel) above 4 is an error.
    +
    + Name-Value Arguments
    + --------------------
    + filename : char
    +     name of the ecModel file (default 'ecModel.yml'). File should be
    +     located in the models/ subfolder of param.path as specified in the
    +     modelAdapter.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter, from where the model folder is read (default:
    +     the current default model adapter).
    +
    + Returns
    + -------
    + model : struct
    +     an ecModel (with ecModel.ec structure).
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     model = loadEcModel(filename, modelAdapter);
    +     model = loadEcModel('filename', filename);
    +
    + See also
    + --------
    + loadConventionalGEM, saveEcModel
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function model = loadEcModel(varargin)
    +0002 % loadEcModel  Load the ecModel that matches the modelAdapter.
    +0003 %
    +0004 % Loads the ecModel that matches the modelAdapter. By default, it loads the
    +0005 % models/ecModel.yml in the directory specified as param.path in the
    +0006 % modelAdapter. Alternative files in the same folder can be loaded by
    +0007 % providing the appropriate filename. If loading models from other
    +0008 % locations, one can directly use readYAMLmodel.
    +0009 %
    +0010 % An ecModel whose protein usage and pool reactions run in the GECKO 3
    +0011 % direction is upgraded in the loaded model with upgradeEcModel, with a
    +0012 % warning. An ecModel format (gecko_format in the file's metaData, see
    +0013 % saveEcModel) above 4 is an error.
    +0014 %
    +0015 % Name-Value Arguments
    +0016 % --------------------
    +0017 % filename : char
    +0018 %     name of the ecModel file (default 'ecModel.yml'). File should be
    +0019 %     located in the models/ subfolder of param.path as specified in the
    +0020 %     modelAdapter.
    +0021 % modelAdapter : ModelAdapter
    +0022 %     a loaded model adapter, from where the model folder is read (default:
    +0023 %     the current default model adapter).
    +0024 %
    +0025 % Returns
    +0026 % -------
    +0027 % model : struct
    +0028 %     an ecModel (with ecModel.ec structure).
    +0029 %
    +0030 % Examples
    +0031 % --------
    +0032 %     % optional arguments may be given positionally or as name-value pairs:
    +0033 %     model = loadEcModel(filename, modelAdapter);
    +0034 %     model = loadEcModel('filename', filename);
    +0035 %
    +0036 % See also
    +0037 % --------
    +0038 % loadConventionalGEM, saveEcModel
    +0039 
    +0040 p = parseGECKOargs(varargin, { ...
    +0041     'filename',     []; ...
    +0042     'modelAdapter', []});
    +0043 filename     = p.filename;
    +0044 modelAdapter = p.modelAdapter;
    +0045 
    +0046 if isempty(modelAdapter)
    +0047     modelAdapter = ModelAdapterManager.getDefault();
    +0048     if isempty(modelAdapter)
    +0049         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0050     end
    +0051 end
    +0052 params = modelAdapter.getParameters();
    +0053 if isempty(filename)
    +0054     filename = 'ecModel.yml';
    +0055 end
    +0056 
    +0057 if ~endsWith(filename,{'yml','yaml'})
    +0058     error(['ecModels should preferably be distributed in YAML file format, ', ...
    +0059            'as otherwise model content will be lost. If the model is in ', ...
    +0060            'SBML format, you can use the usual importModel function to load ', ...
    +0061            'this as any other genome-scale model.'])
    +0062 end
    +0063 
    +0064 filename = fullfile(params.path,'models',filename); 
    +0065 if endsWith(filename,{'yml','yaml'})
    +0066     model = readYAMLmodel(filename);
    +0067 elseif endsWith(filename,{'xml','sbml'})
    +0068     model = importModel(filename);
    +0069 end
    +0070 
    +0071 if isfield(model, 'annotation') && isfield(model.annotation, 'gecko_format') ...
    +0072         && str2double(model.annotation.gecko_format) > 4
    +0073     writer = 'an unknown release';
    +0074     if isfield(model.annotation, 'generator')
    +0075         writer = model.annotation.generator;
    +0076     end
    +0077     error('loadEcModel:format', ['%s has ecModel format %s (written by %s); ' ...
    +0078         'this GECKO reads format 4 and older. Update GECKO to load it.'], ...
    +0079         filename, model.annotation.gecko_format, writer)
    +0080 end
    +0081 [model, changed] = upgradeEcModel(model);
    +0082 if ~isempty(changed)
    +0083     warning('loadEcModel:upgraded', ['%s has %d protein usage and pool reactions in the GECKO 3 ' ...
    +0084         'direction; they are turned forward in the loaded model. upgradeGECKOproject upgrades the ' ...
    +0085         'files of the project.'], filename, numel(changed))
    +0086 end
    +0087 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/io/loadFluxData.html b/doc/src/io/loadFluxData.html new file mode 100644 index 00000000..7232ecc0 --- /dev/null +++ b/doc/src/io/loadFluxData.html @@ -0,0 +1,200 @@ + + + + Description of loadFluxData + + + + + + + + + +
    Home > src > io > loadFluxData.m
    + + + +

    loadFluxData +

    + +

    PURPOSE ^

    +
    loadFluxData Load total protein measurements and exchange flux data.
    + +

    SYNOPSIS ^

    +
    function fluxData = loadFluxData(varargin)
    + +

    DESCRIPTION ^

    +
     loadFluxData  Load total protein measurements and exchange flux data.
    +
    + Loads total protein content and exchange flux data (e.g. carbon source,
    + O2, CO2) from a tab-delimited file.
    +
    + Name-Value Arguments
    + --------------------
    + fluxDataFile : char
    +     path to file with flux data (default reads data/fluxData.tsv as
    +     specified in modelAdapter).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + fluxData : struct
    +     structure with flux data.
    +
    + Notes
    + -----
    + The fluxData structure has the following fields:
    +
    + - conds : sampling condition.
    + - Ptot : total protein (g/gDCW).
    + - grRate : growth rate (1/h).
    + - exchFluxes : exchange fluxes (mmol/gDCWh).
    + - exchMets : exchanged metabolites, matching exchFluxes.
    + - exchRxnIDs : exchange reaction IDs, matching exchMets.
    + - evotuneRMSEweight : if column existed in fluxData.tsv, weights for RMSE calculation in evotune kcat tuning.
    + - source : if column existed in fluxData.tsv, description where the data comes from.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     fluxData = loadFluxData(fluxDataFile, modelAdapter);
    +     fluxData = loadFluxData('fluxDataFile', fluxDataFile);
    +
    + See also
    + --------
    + loadProtData
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function fluxData = loadFluxData(varargin)
    +0002 % loadFluxData  Load total protein measurements and exchange flux data.
    +0003 %
    +0004 % Loads total protein content and exchange flux data (e.g. carbon source,
    +0005 % O2, CO2) from a tab-delimited file.
    +0006 %
    +0007 % Name-Value Arguments
    +0008 % --------------------
    +0009 % fluxDataFile : char
    +0010 %     path to file with flux data (default reads data/fluxData.tsv as
    +0011 %     specified in modelAdapter).
    +0012 % modelAdapter : ModelAdapter
    +0013 %     a loaded model adapter (default: the current default model adapter).
    +0014 %
    +0015 % Returns
    +0016 % -------
    +0017 % fluxData : struct
    +0018 %     structure with flux data.
    +0019 %
    +0020 % Notes
    +0021 % -----
    +0022 % The fluxData structure has the following fields:
    +0023 %
    +0024 % - conds : sampling condition.
    +0025 % - Ptot : total protein (g/gDCW).
    +0026 % - grRate : growth rate (1/h).
    +0027 % - exchFluxes : exchange fluxes (mmol/gDCWh).
    +0028 % - exchMets : exchanged metabolites, matching exchFluxes.
    +0029 % - exchRxnIDs : exchange reaction IDs, matching exchMets.
    +0030 % - evotuneRMSEweight : if column existed in fluxData.tsv, weights for RMSE calculation in evotune kcat tuning.
    +0031 % - source : if column existed in fluxData.tsv, description where the data comes from.
    +0032 %
    +0033 % Examples
    +0034 % --------
    +0035 %     % optional arguments may be given positionally or as name-value pairs:
    +0036 %     fluxData = loadFluxData(fluxDataFile, modelAdapter);
    +0037 %     fluxData = loadFluxData('fluxDataFile', fluxDataFile);
    +0038 %
    +0039 % See also
    +0040 % --------
    +0041 % loadProtData
    +0042 
    +0043 p = parseGECKOargs(varargin, { ...
    +0044     'fluxDataFile', []; ...
    +0045     'modelAdapter', []});
    +0046 fluxDataFile = p.fluxDataFile;
    +0047 modelAdapter = p.modelAdapter;
    +0048 
    +0049 if isempty(modelAdapter)
    +0050     modelAdapter = ModelAdapterManager.getDefault();
    +0051     if isempty(modelAdapter)
    +0052         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0053     end
    +0054 end
    +0055 params = modelAdapter.getParameters();
    +0056 
    +0057 if isempty(fluxDataFile)
    +0058     fluxDataFile = fullfile(params.path,'data','fluxData.tsv');
    +0059 end
    +0060 
    +0061 %Load total protein content and flux data
    +0062 try
    +0063     fID       = fopen(fluxDataFile);
    +0064     formatStr = '%s';
    +0065     data      = textscan(fID,formatStr,'Delimiter','\n');
    +0066     fclose(fID);
    +0067 catch
    +0068     warning('Failed to load %s.',fluxDataFile);
    +0069     fluxData = [];
    +0070     return
    +0071 end
    +0072 fluxDataRaw  = [];
    +0073 for i=1:length(data{1})
    +0074     row      = data{1}(i);
    +0075     row      = strsplit(row{1},'\t');
    +0076     row      = row(1:end);
    +0077     fluxDataRaw = [fluxDataRaw; row]; 
    +0078 end
    +0079 if size(fluxDataRaw,2) == 0
    +0080     error('The input file %s is likely not tab-delimited.', fluxDataFile)
    +0081 end
    +0082 fluxData            = [];
    +0083 
    +0084 %Find additional fields
    +0085 extraFieldNames     = {'evotuneRMSEweight','source'};
    +0086 extraFieldNumeric   = [true,false];      
    +0087 [logicalExtra, extraFields]    = ismember(extraFieldNames,fluxDataRaw(1,:));
    +0088 extraFields(~logicalExtra) = [];
    +0089 extraFieldNames(~logicalExtra) = [];
    +0090 extraFieldNumeric(~logicalExtra) = [];
    +0091 if any(extraFields)
    +0092     for i=1:numel(extraFields)
    +0093         if extraFieldNumeric(i)
    +0094             fluxData.(extraFieldNames{i}) = str2double(fluxDataRaw(2:end,extraFields(i)));
    +0095         else
    +0096             fluxData.(extraFieldNames{i}) = fluxDataRaw(2:end,extraFields(i));
    +0097         end
    +0098     end
    +0099     fluxDataRaw(:,extraFields) = [];
    +0100 end
    +0101 
    +0102 %Extract observed byProduct names from file
    +0103 exchRxns = fluxDataRaw(1,4:end);
    +0104 exchMets = strtrim(regexprep(exchRxns,'(.*)\(.*\)$','$1'));
    +0105 exchRxns = regexprep(exchRxns,'.*\((.*)\)$','$1');
    +0106 
    +0107 fluxData.conds      = fluxDataRaw(2:end,1);
    +0108 fluxData.Ptot       = str2double(fluxDataRaw(2:end,2));
    +0109 fluxData.grRate     = str2double(fluxDataRaw(2:end,3));
    +0110 fluxData.exchFluxes = str2double(fluxDataRaw(2:end,4:end));
    +0111 %fluxData.exchFluxes(isnan(fluxData.exchFluxes)) = 0;
    +0112 fluxData.exchMets   = exchMets;
    +0113 fluxData.exchRxnIDs = exchRxns;
    +0114 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/io/loadProtData.html b/doc/src/io/loadProtData.html new file mode 100644 index 00000000..6380cea0 --- /dev/null +++ b/doc/src/io/loadProtData.html @@ -0,0 +1,291 @@ + + + + Description of loadProtData + + + + + + + + + +
    Home > src > io > loadProtData.m
    + + + +

    loadProtData +

    + +

    PURPOSE ^

    +
    loadProtData Load absolute proteomics data and average over replicates.
    + +

    SYNOPSIS ^

    +
    function protData = loadProtData(replPerCond, varargin)
    + +

    DESCRIPTION ^

    +
     loadProtData  Load absolute proteomics data and average over replicates.
    +
    + Loads absolute proteomics data (in mg/gDCW) and returns mean values
    + across replicates for each condition in the data file. By default it also
    + filters the data by various criteria, to remove uncertain data (see input
    + parameters).
    +
    + Parameters
    + ----------
    + replPerCond : double
    +     vector with number of replicates for each condition in the dataset.
    +     Example: [3, 2] if first condition has triplicates and second
    +     condition has duplicates.
    +
    + Name-Value Arguments
    + --------------------
    + protDataFile : char
    +     path to file with proteomics data, where protein levels are in
    +     mg/gDCW (default reads data/proteomics.tsv as specified in
    +     modelAdapter). Alternatively, protDataFile can be a protData structure
    +     that was previously made by loadProtData.
    + filterData : logical
    +     whether abundances should be filtered. If false, minVal, maxRSD,
    +     maxMissing, cutLowest and addStdevs are not considered (default true).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + minVal : double
    +     minimum mean protein measurement per condition; proteins with a lower
    +     mean abundance are discarded (set to NaN) for that condition (default
    +     0, i.e. no lower threshold).
    + maxRSD : double
    +     maximum relative standard deviation (RSD, the standard deviation
    +     across replicates divided by their mean) allowed per condition;
    +     proteins exceeding it are discarded (set to NaN) for that condition
    +     (default 1, i.e. RSD up to 100%).
    + maxMissing : double
    +     minimum fraction of replicates within a condition that must have a
    +     measured value; proteins with fewer present replicates than this
    +     fraction requires are discarded (set to NaN) for that condition
    +     (default 2/3, i.e. at least two of three replicates must have a
    +     value). If conditions have different number of replicates (as
    +     indicated in replPerCond), maxMissing can also be a vector of the
    +     same length as replPerCond, with individual values per condition.
    + cutLowest : double
    +     percentage of lowest mean values per condition to be discarded (not
    +     considering NaN values) (default 5).
    + addStdevs : double
    +     how many standard deviations should be added to the mean value of
    +     each protein measurement across replicates, broadening the confidence
    +     interval (default 1).
    +
    + Returns
    + -------
    + protData : struct
    +     structure with (filtered) proteome data.
    +
    + Notes
    + -----
    + The protData structure has the following fields:
    +
    + - uniprotIDs : cell array with Uniprot IDs matching protData.abundances.
    + - abundances : matrix of proteomics data, where each column contains mean abundances per condition.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     protData = loadProtData(replPerCond, protDataFile, filterData, modelAdapter, minVal, maxRSD, maxMissing, cutLowest, addStdevs);
    +     protData = loadProtData(replPerCond, 'filterData', false);
    +
    + See also
    + --------
    + loadFluxData
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function protData = loadProtData(replPerCond, varargin)
    +0002 % loadProtData  Load absolute proteomics data and average over replicates.
    +0003 %
    +0004 % Loads absolute proteomics data (in mg/gDCW) and returns mean values
    +0005 % across replicates for each condition in the data file. By default it also
    +0006 % filters the data by various criteria, to remove uncertain data (see input
    +0007 % parameters).
    +0008 %
    +0009 % Parameters
    +0010 % ----------
    +0011 % replPerCond : double
    +0012 %     vector with number of replicates for each condition in the dataset.
    +0013 %     Example: [3, 2] if first condition has triplicates and second
    +0014 %     condition has duplicates.
    +0015 %
    +0016 % Name-Value Arguments
    +0017 % --------------------
    +0018 % protDataFile : char
    +0019 %     path to file with proteomics data, where protein levels are in
    +0020 %     mg/gDCW (default reads data/proteomics.tsv as specified in
    +0021 %     modelAdapter). Alternatively, protDataFile can be a protData structure
    +0022 %     that was previously made by loadProtData.
    +0023 % filterData : logical
    +0024 %     whether abundances should be filtered. If false, minVal, maxRSD,
    +0025 %     maxMissing, cutLowest and addStdevs are not considered (default true).
    +0026 % modelAdapter : ModelAdapter
    +0027 %     a loaded model adapter (default: the current default model adapter).
    +0028 % minVal : double
    +0029 %     minimum mean protein measurement per condition; proteins with a lower
    +0030 %     mean abundance are discarded (set to NaN) for that condition (default
    +0031 %     0, i.e. no lower threshold).
    +0032 % maxRSD : double
    +0033 %     maximum relative standard deviation (RSD, the standard deviation
    +0034 %     across replicates divided by their mean) allowed per condition;
    +0035 %     proteins exceeding it are discarded (set to NaN) for that condition
    +0036 %     (default 1, i.e. RSD up to 100%).
    +0037 % maxMissing : double
    +0038 %     minimum fraction of replicates within a condition that must have a
    +0039 %     measured value; proteins with fewer present replicates than this
    +0040 %     fraction requires are discarded (set to NaN) for that condition
    +0041 %     (default 2/3, i.e. at least two of three replicates must have a
    +0042 %     value). If conditions have different number of replicates (as
    +0043 %     indicated in replPerCond), maxMissing can also be a vector of the
    +0044 %     same length as replPerCond, with individual values per condition.
    +0045 % cutLowest : double
    +0046 %     percentage of lowest mean values per condition to be discarded (not
    +0047 %     considering NaN values) (default 5).
    +0048 % addStdevs : double
    +0049 %     how many standard deviations should be added to the mean value of
    +0050 %     each protein measurement across replicates, broadening the confidence
    +0051 %     interval (default 1).
    +0052 %
    +0053 % Returns
    +0054 % -------
    +0055 % protData : struct
    +0056 %     structure with (filtered) proteome data.
    +0057 %
    +0058 % Notes
    +0059 % -----
    +0060 % The protData structure has the following fields:
    +0061 %
    +0062 % - uniprotIDs : cell array with Uniprot IDs matching protData.abundances.
    +0063 % - abundances : matrix of proteomics data, where each column contains mean abundances per condition.
    +0064 %
    +0065 % Examples
    +0066 % --------
    +0067 %     % optional arguments may be given positionally or as name-value pairs:
    +0068 %     protData = loadProtData(replPerCond, protDataFile, filterData, modelAdapter, minVal, maxRSD, maxMissing, cutLowest, addStdevs);
    +0069 %     protData = loadProtData(replPerCond, 'filterData', false);
    +0070 %
    +0071 % See also
    +0072 % --------
    +0073 % loadFluxData
    +0074 
    +0075 p = parseGECKOargs(varargin, { ...
    +0076     'protDataFile', []; ...
    +0077     'filterData',   true; ...
    +0078     'modelAdapter', []; ...
    +0079     'minVal',       0; ...
    +0080     'maxRSD',       1; ...
    +0081     'maxMissing',   2/3; ...
    +0082     'cutLowest',    5; ...
    +0083     'addStdevs',    1});
    +0084 protDataFile = p.protDataFile;
    +0085 filterData   = p.filterData;
    +0086 modelAdapter = p.modelAdapter;
    +0087 minVal       = p.minVal;
    +0088 maxRSD       = p.maxRSD;
    +0089 maxMissing   = p.maxMissing;
    +0090 cutLowest    = p.cutLowest;
    +0091 addStdevs    = p.addStdevs;
    +0092 
    +0093 if isempty(modelAdapter)
    +0094     modelAdapter = ModelAdapterManager.getDefault();
    +0095     if isempty(modelAdapter)
    +0096         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0097     end
    +0098 end
    +0099 params = modelAdapter.getParameters();
    +0100 
    +0101 if isempty(protDataFile)
    +0102     protDataFile = fullfile(params.path,'data','proteomics.tsv');
    +0103 end
    +0104 
    +0105 format = '%s';
    +0106 for i=1:sum(replPerCond)
    +0107     format = [format ' %f'];
    +0108 end
    +0109 if ~isstruct(protDataFile)
    +0110     checkFileExistence(protDataFile);
    +0111     fID         = fopen(protDataFile);
    +0112     protDataRaw = textscan(fID,format,'Delimiter','\t','HeaderLines',1,'TreatAsEmpty',{'NA','na','NaN','#VALUE!'});
    +0113     uniprotIDs  = protDataRaw{1};
    +0114     abundances  = cell2mat(protDataRaw(2:end));
    +0115     fclose(fID);
    +0116 else
    +0117     uniprotIDs  = protDataFile.uniprotIDs;
    +0118     abundances  = protDataFile.abundances;
    +0119 end
    +0120 
    +0121 %Remove entriew without ID
    +0122 remData = cellfun(@isempty,uniprotIDs);
    +0123 uniprotIDs(remData,:) = [];
    +0124 abundances(remData,:) = [];
    +0125 m                     = size(abundances,1);
    +0126 filtAbund             = nan(m,numel(replPerCond));
    +0127 
    +0128 if filterData
    +0129     for i=1:numel(replPerCond)
    +0130         condAbund    = abundances(:,1:replPerCond(i));
    +0131         if i<numel(replPerCond)
    +0132             abundances   = abundances(:,replPerCond(i)+1:end);
    +0133         end
    +0134         % First filter maxMissing
    +0135         if size(condAbund,2) > 1
    +0136             if numel(maxMissing)>1
    +0137                 maxMisRepl = maxMissing(i);
    +0138             else
    +0139                 maxMisRepl = maxMissing;
    +0140             end
    +0141             remData = sum(condAbund>0,2)<maxMisRepl*size(condAbund,2);
    +0142             condAbund(remData,:) = nan;
    +0143         end
    +0144         % Filter by RSD
    +0145         remData = (std(condAbund,0,2,'omitnan')./mean(condAbund,2,'omitnan'))>maxRSD;
    +0146         condAbund(remData,:) = nan;
    +0147         % Add stdevs
    +0148         condAbund = mean(condAbund,2,'omitnan')+(addStdevs*std(condAbund,0,2,'omitnan'));
    +0149         % Filter by minVal
    +0150         remData = mean(condAbund,2,'omitnan')<minVal;
    +0151         condAbund(remData) = nan;
    +0152         % Remove the lowest cutLowest percent
    +0153         numData  = find(~isnan(condAbund));
    +0154         [~,sortData] = sort(condAbund);
    +0155         lowCutoff = floor(numel(numData)*cutLowest/100);
    +0156         condAbund(sortData(1:lowCutoff)) = nan;
    +0157         % Combine conditions
    +0158         filtAbund(:,i) = condAbund;
    +0159     end
    +0160 else
    +0161     for i=1:numel(replPerCond)
    +0162         condAbund    = abundances(:,1:replPerCond(i));
    +0163         if i<numel(replPerCond)
    +0164             abundances = abundances(:,replPerCond(i)+1:end);
    +0165         end
    +0166         filtAbund(:,i) = mean(condAbund,2,'omitnan');
    +0167     end
    +0168 end
    +0169 notAllNan = logical(sum(~isnan(filtAbund),2));
    +0170 protData.abundances = filtAbund(notAllNan,:);
    +0171 protData.uniprotIDs = uniprotIDs(notAllNan);
    +0172 end
    +0173
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/io/saveEcModel.html b/doc/src/io/saveEcModel.html new file mode 100644 index 00000000..6df2cd14 --- /dev/null +++ b/doc/src/io/saveEcModel.html @@ -0,0 +1,194 @@ + + + + Description of saveEcModel + + + + + + + + + +
    Home > src > io > saveEcModel.m
    + + + +

    saveEcModel +

    + +

    PURPOSE ^

    +
    saveEcModel Save an ecModel in YAML and/or SBML format.
    + +

    SYNOPSIS ^

    +
    function saveEcModel(ecModel,varargin)
    + +

    DESCRIPTION ^

    +
     saveEcModel  Save an ecModel in YAML and/or SBML format.
    +
    + Saves the ecModel in either YAML format (= default and preferred, as all
    + ecModel content is reserved) and/or SBML format (= more widely compatible
    + with other constraint-based modelling tools, can be used for running
    + simulations like FBA etc., but this model cannot be loaded back into
    + MATLAB for applying further GECKO functions, as model.ec is lost).
    +
    + A YAML file records its ecModel format (gecko_format, see loadEcModel)
    + and the GECKO release that wrote it (generator) in its metaData, in
    + place of the geckopy_version that earlier geckopy releases wrote.
    +
    + The ecModel is saved to the ecModel-specific models/ subfolder. For
    + saving to other locations, writeYAMLmodel or exportModel are more
    + suitable.
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     an ecModel (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + filename : char
    +     ending with either .yml or .xml, specifying if the ecModel should be
    +     saved in YAML or SBML file format. If no file extension is given, the
    +     ecModel will be saved in YAML format. If no filename is given,
    +     'ecModel.yml' is used.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter, from where the model folder is read (default:
    +     the current default model adapter).
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     saveEcModel(ecModel,filename,modelAdapter);
    +     saveEcModel(ecModel,'filename',filename);
    +
    + See also
    + --------
    + loadEcModel
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function saveEcModel(ecModel,varargin)
    +0002 % saveEcModel  Save an ecModel in YAML and/or SBML format.
    +0003 %
    +0004 % Saves the ecModel in either YAML format (= default and preferred, as all
    +0005 % ecModel content is reserved) and/or SBML format (= more widely compatible
    +0006 % with other constraint-based modelling tools, can be used for running
    +0007 % simulations like FBA etc., but this model cannot be loaded back into
    +0008 % MATLAB for applying further GECKO functions, as model.ec is lost).
    +0009 %
    +0010 % A YAML file records its ecModel format (gecko_format, see loadEcModel)
    +0011 % and the GECKO release that wrote it (generator) in its metaData, in
    +0012 % place of the geckopy_version that earlier geckopy releases wrote.
    +0013 %
    +0014 % The ecModel is saved to the ecModel-specific models/ subfolder. For
    +0015 % saving to other locations, writeYAMLmodel or exportModel are more
    +0016 % suitable.
    +0017 %
    +0018 % Parameters
    +0019 % ----------
    +0020 % ecModel : struct
    +0021 %     an ecModel (with ecModel.ec structure).
    +0022 %
    +0023 % Name-Value Arguments
    +0024 % --------------------
    +0025 % filename : char
    +0026 %     ending with either .yml or .xml, specifying if the ecModel should be
    +0027 %     saved in YAML or SBML file format. If no file extension is given, the
    +0028 %     ecModel will be saved in YAML format. If no filename is given,
    +0029 %     'ecModel.yml' is used.
    +0030 % modelAdapter : ModelAdapter
    +0031 %     a loaded model adapter, from where the model folder is read (default:
    +0032 %     the current default model adapter).
    +0033 %
    +0034 % Examples
    +0035 % --------
    +0036 %     % optional arguments may be given positionally or as name-value pairs:
    +0037 %     saveEcModel(ecModel,filename,modelAdapter);
    +0038 %     saveEcModel(ecModel,'filename',filename);
    +0039 %
    +0040 % See also
    +0041 % --------
    +0042 % loadEcModel
    +0043 
    +0044 p = parseGECKOargs(varargin, { ...
    +0045     'filename',     []; ...
    +0046     'modelAdapter', []});
    +0047 filename     = p.filename;
    +0048 modelAdapter = p.modelAdapter;
    +0049 
    +0050 if isempty(modelAdapter)
    +0051     modelAdapter = ModelAdapterManager.getDefault();
    +0052     if isempty(modelAdapter)
    +0053         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0054     end
    +0055 end
    +0056 params = modelAdapter.getParameters();
    +0057 if isempty(filename)
    +0058     filename = 'ecModel';
    +0059 end
    +0060 filename = fullfile(params.path,'models',filename);
    +0061 
    +0062 switch filename(end-3:end)
    +0063     case {'.xml','sbml'}
    +0064         exportModel(ecModel, filename);
    +0065         %Convert notation "e-005" to "e-05 " in stoich. coeffs. to avoid
    +0066         %inconsistencies between Windows and MAC:
    +0067         copyfile(filename,'backup.xml')
    +0068         fin  = fopen('backup.xml', 'r');
    +0069         fout = fopen(filename, 'w');
    +0070         still_reading = true;
    +0071         while still_reading
    +0072             inline = fgets(fin);
    +0073             if ~ischar(inline)
    +0074                 still_reading = false;
    +0075             else
    +0076                 if ~isempty(regexp(inline,'-00[0-9]','once'))
    +0077                     inline = strrep(inline,'-00','-0');
    +0078                 elseif ~isempty(regexp(inline,'-01[0-9]','once'))
    +0079                     inline = strrep(inline,'-01','-1');
    +0080                 end
    +0081                 fwrite(fout, inline);
    +0082             end
    +0083         end
    +0084         fclose('all');
    +0085         delete('backup.xml');
    +0086     otherwise % Assume YAML
    +0087         % The ecModel format the file follows (as project_format in
    +0088         % model_adapter.toml) and the release that wrote it.
    +0089         ecModel.annotation.gecko_format = '4';
    +0090         ecModel.annotation.generator = ['GECKO ' geckoVersion()];
    +0091         if isfield(ecModel.annotation, 'geckopy_version')
    +0092             ecModel.annotation = rmfield(ecModel.annotation, 'geckopy_version');
    +0093         end
    +0094         writeYAMLmodel(ecModel,filename);
    +0095 end
    +0096 end
    +0097 
    +0098 function v = geckoVersion()
    +0099 file = fullfile(findGECKOroot, 'version.txt');
    +0100 if isfile(file)
    +0101     v = strtrim(fileread(file));
    +0102 else
    +0103     v = 'unknown';
    +0104 end
    +0105 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/evotune/bestParsimonious.html b/doc/src/kcat_tuning/evotune/bestParsimonious.html new file mode 100644 index 00000000..67846d00 --- /dev/null +++ b/doc/src/kcat_tuning/evotune/bestParsimonious.html @@ -0,0 +1,112 @@ + + + + Description of bestParsimonious + + + + + + + + + +
    Home > src > kcat_tuning > evotune > bestParsimonious.m
    + + + +

    bestParsimonious +

    + +

    PURPOSE ^

    +
    bestParsimonious The fewest-changes point whose RMSE is within
    + +

    SYNOPSIS ^

    +
    function point = bestParsimonious(points,varargin)
    + +

    DESCRIPTION ^

    +
     bestParsimonious  The fewest-changes point whose RMSE is within
    + tolerance of the best on a parsimonyFrontier.
    +
    + Defaults to 2%, which is the scale of alternate-optimum noise typically
    + seen from re-solving an LP with a slightly different kcat vector --
    + below that, two vectors are not meaningfully different in fit, so the
    + sparser one wins.
    +
    + Parameters
    + ----------
    + points : struct array
    +     as returned by parsimonyFrontier.
    +
    + Name-Value Arguments
    + --------------------
    + tolerance : double
    +     default 0.02.
    +
    + Returns
    + -------
    + point : struct
    +     the chosen entry of points.
    +
    + See also
    + --------
    + parsimonyFrontier
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function point = bestParsimonious(points,varargin)
    +0002 % bestParsimonious  The fewest-changes point whose RMSE is within
    +0003 % tolerance of the best on a parsimonyFrontier.
    +0004 %
    +0005 % Defaults to 2%, which is the scale of alternate-optimum noise typically
    +0006 % seen from re-solving an LP with a slightly different kcat vector --
    +0007 % below that, two vectors are not meaningfully different in fit, so the
    +0008 % sparser one wins.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % points : struct array
    +0013 %     as returned by parsimonyFrontier.
    +0014 %
    +0015 % Name-Value Arguments
    +0016 % --------------------
    +0017 % tolerance : double
    +0018 %     default 0.02.
    +0019 %
    +0020 % Returns
    +0021 % -------
    +0022 % point : struct
    +0023 %     the chosen entry of points.
    +0024 %
    +0025 % See also
    +0026 % --------
    +0027 % parsimonyFrontier
    +0028 p = parseGECKOargs(varargin, { ...
    +0029     'tolerance', 0.02});
    +0030 tolerance = p.tolerance;
    +0031 
    +0032 if isempty(points)
    +0033     error('points is empty.')
    +0034 end
    +0035 rmses = [points.rmse];
    +0036 bestRmse = min(rmses);
    +0037 within = points(rmses <= bestRmse * (1+tolerance));
    +0038 [~,idx] = min([within.nChanged]);
    +0039 point = within(idx);
    +0040 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/evotune/cmaesKcatTuning.html b/doc/src/kcat_tuning/evotune/cmaesKcatTuning.html new file mode 100644 index 00000000..1ad5de2d --- /dev/null +++ b/doc/src/kcat_tuning/evotune/cmaesKcatTuning.html @@ -0,0 +1,391 @@ + + + + Description of cmaesKcatTuning + + + + + + + + + +
    Home > src > kcat_tuning > evotune > cmaesKcatTuning.m
    + + + +

    cmaesKcatTuning +

    + +

    PURPOSE ^

    +
    cmaesKcatTuning Tune kcats against experimental data with CMA-ES.
    + +

    SYNOPSIS ^

    +
    function [ecModel,result] = cmaesKcatTuning(ecModel,varargin)
    + +

    DESCRIPTION ^

    +
     cmaesKcatTuning  Tune kcats against experimental data with CMA-ES.
    +
    + Configuration comes entirely from modelAdapter.params.evotune: trust
    + tiers (kcatSources/sigma0logSource/sigma0logDefault), maxGrowthWeight,
    + priorPenaltyWeight and tieIsozymes control the search, and
    + maxGenerations/rmseThreshold are its stopping conditions.
    +
    + Vendors a separable (diagonal-covariance) CMA-ES -- MATLAB has no
    + built-in implementation and Global Optimization Toolbox doesn't ship
    + one either. Separable rather than full-covariance because that is what
    + geckopy's own port actually runs (cma's CMA_diagonal=True) and what its
    + defaults were validated against; it is also lower risk to implement
    + correctly. See the "CMA-ES core" local functions below.
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     ecModel with a populated ec.kcat.
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + evoData : struct
    +     as returned by loadEvotuneData (default: loaded from modelAdapter).
    + tunableMask, screen, targetImpactShare
    +     control which kcats are searched over, in order of precedence. Pass
    +     tunableMask to fix the set yourself. Otherwise, a mask is built by
    +     selectTunableMask at targetImpactShare (default 0.9), from screen if
    +     given, or from a fresh screenKcatLeverage call otherwise.
    + popsize : double
    +     CMA-ES population size. Defaults to 4 + floor(3*log(n)), the
    +     standard dimension-scaled default, so it adapts to however many
    +     free parameters the mask/tying produced.
    + nProc : double
    +     number of parallel workers used to score each generation's
    +     candidates (default 1, i.e. serial). Requires Parallel Computing
    +     Toolbox for > 1.
    + seed : double
    +     if given, seeds the random draws for a reproducible run.
    + verbose : logical
    +     whether per-generation progress is printed (default true).
    +
    + Returns
    + -------
    + ecModel : struct
    +     mutated: tunable rows carry the best kcat vector CMA-ES found, with
    +     kcat constraints already applied. MATLAB structs are copied on
    +     assignment, so -- unlike geckopy's in-place mutation -- this output
    +     must be captured by the caller.
    + result : struct
    +     rxns/oldKcat/newKcat/groups cover the selected tunable set, tied
    +     groups included (their members share one value in newKcat).
    +     rmseTrace/objectiveTrace record the best-so-far plain RMSE and
    +     optimised objective per generation. nGenerations is how many
    +     generations actually ran. converged is true if
    +     rmseTrace(end) <= params.rmseThreshold.
    +
    + Raises
    + ------
    + error
    +     if there are no tunable kcats, or fewer than two free parameters
    +     remain after masking and tying -- too little for CMA-ES to search
    +     over.
    +
    + See also
    + --------
    + screenKcatLeverage, selectTunableMask, tunePriorPenaltyWeight
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • evotuneScore evotuneScore Score one ecModel's current kcats against evotune data.
    • loadEvotuneData loadEvotuneData Load experimental data for evotune (CMA-ES) kcat tuning.
    • resolveTunableContext resolveTunableContext The tunable kcat subset plus everything derived
    • screenKcatLeverage screenKcatLeverage Report which kcats the data can actually speak to.
    • selectTunableMask selectTunableMask Build a tunableMask from a screenKcatLeverage report.
    +This function is called by: + + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [ecModel,result] = cmaesKcatTuning(ecModel,varargin)
    +0002 % cmaesKcatTuning  Tune kcats against experimental data with CMA-ES.
    +0003 %
    +0004 % Configuration comes entirely from modelAdapter.params.evotune: trust
    +0005 % tiers (kcatSources/sigma0logSource/sigma0logDefault), maxGrowthWeight,
    +0006 % priorPenaltyWeight and tieIsozymes control the search, and
    +0007 % maxGenerations/rmseThreshold are its stopping conditions.
    +0008 %
    +0009 % Vendors a separable (diagonal-covariance) CMA-ES -- MATLAB has no
    +0010 % built-in implementation and Global Optimization Toolbox doesn't ship
    +0011 % one either. Separable rather than full-covariance because that is what
    +0012 % geckopy's own port actually runs (cma's CMA_diagonal=True) and what its
    +0013 % defaults were validated against; it is also lower risk to implement
    +0014 % correctly. See the "CMA-ES core" local functions below.
    +0015 %
    +0016 % Parameters
    +0017 % ----------
    +0018 % ecModel : struct
    +0019 %     ecModel with a populated ec.kcat.
    +0020 %
    +0021 % Name-Value Arguments
    +0022 % --------------------
    +0023 % modelAdapter : ModelAdapter
    +0024 %     a loaded model adapter (default: the current default model adapter).
    +0025 % evoData : struct
    +0026 %     as returned by loadEvotuneData (default: loaded from modelAdapter).
    +0027 % tunableMask, screen, targetImpactShare
    +0028 %     control which kcats are searched over, in order of precedence. Pass
    +0029 %     tunableMask to fix the set yourself. Otherwise, a mask is built by
    +0030 %     selectTunableMask at targetImpactShare (default 0.9), from screen if
    +0031 %     given, or from a fresh screenKcatLeverage call otherwise.
    +0032 % popsize : double
    +0033 %     CMA-ES population size. Defaults to 4 + floor(3*log(n)), the
    +0034 %     standard dimension-scaled default, so it adapts to however many
    +0035 %     free parameters the mask/tying produced.
    +0036 % nProc : double
    +0037 %     number of parallel workers used to score each generation's
    +0038 %     candidates (default 1, i.e. serial). Requires Parallel Computing
    +0039 %     Toolbox for > 1.
    +0040 % seed : double
    +0041 %     if given, seeds the random draws for a reproducible run.
    +0042 % verbose : logical
    +0043 %     whether per-generation progress is printed (default true).
    +0044 %
    +0045 % Returns
    +0046 % -------
    +0047 % ecModel : struct
    +0048 %     mutated: tunable rows carry the best kcat vector CMA-ES found, with
    +0049 %     kcat constraints already applied. MATLAB structs are copied on
    +0050 %     assignment, so -- unlike geckopy's in-place mutation -- this output
    +0051 %     must be captured by the caller.
    +0052 % result : struct
    +0053 %     rxns/oldKcat/newKcat/groups cover the selected tunable set, tied
    +0054 %     groups included (their members share one value in newKcat).
    +0055 %     rmseTrace/objectiveTrace record the best-so-far plain RMSE and
    +0056 %     optimised objective per generation. nGenerations is how many
    +0057 %     generations actually ran. converged is true if
    +0058 %     rmseTrace(end) <= params.rmseThreshold.
    +0059 %
    +0060 % Raises
    +0061 % ------
    +0062 % error
    +0063 %     if there are no tunable kcats, or fewer than two free parameters
    +0064 %     remain after masking and tying -- too little for CMA-ES to search
    +0065 %     over.
    +0066 %
    +0067 % See also
    +0068 % --------
    +0069 % screenKcatLeverage, selectTunableMask, tunePriorPenaltyWeight
    +0070 p = parseGECKOargs(varargin, { ...
    +0071     'modelAdapter', []; ...
    +0072     'evoData', []; ...
    +0073     'tunableMask', []; ...
    +0074     'screen', []; ...
    +0075     'targetImpactShare', 0.9; ...
    +0076     'popsize', []; ...
    +0077     'nProc', 1; ...
    +0078     'seed', []; ...
    +0079     'verbose', true});
    +0080 modelAdapter      = p.modelAdapter;
    +0081 evoData           = p.evoData;
    +0082 tunableMask       = p.tunableMask;
    +0083 screen            = p.screen;
    +0084 targetImpactShare = p.targetImpactShare;
    +0085 popsize           = p.popsize;
    +0086 nProc             = max(1, round(p.nProc));
    +0087 seed              = p.seed;
    +0088 verbose           = p.verbose;
    +0089 
    +0090 if isempty(modelAdapter)
    +0091     modelAdapter = ModelAdapterManager.getDefault();
    +0092     if isempty(modelAdapter)
    +0093         error('Either send in a modelAdapter or set the default ecModel adapter in the ModelAdapterManager.')
    +0094     end
    +0095 end
    +0096 params = modelAdapter.params.evotune;
    +0097 if isempty(evoData)
    +0098     evoData = loadEvotuneData('modelAdapter', modelAdapter);
    +0099 end
    +0100 
    +0101 if isempty(tunableMask)
    +0102     if isempty(screen)
    +0103         screen = screenKcatLeverage(ecModel, 'modelAdapter',modelAdapter, ...
    +0104             'evoData',evoData, 'nProc',nProc);
    +0105     end
    +0106     tunableMask = selectTunableMask(ecModel, screen, 'targetImpactShare',targetImpactShare);
    +0107 end
    +0108 
    +0109 [tunableIdx,ecRxnIdsTunable,kcat0,groups,sigma0log,tieMap] = ...
    +0110     resolveTunableContext(ecModel,params,tunableMask);
    +0111 
    +0112 reps = find(tieMap == (1:numel(tieMap))');
    +0113 if numel(reps) < 2
    +0114     error('Only %d free parameter(s) after masking and tying; too few for CMA-ES. Widen tunableMask/targetImpactShare.', numel(reps))
    +0115 end
    +0116 [~,assign] = ismember(tieMap, reps);  % assign(i): which column of reps tieMap(i) follows
    +0117 
    +0118 n = numel(reps);
    +0119 x0  = log(kcat0(reps));
    +0120 sig = sigma0log(reps);
    +0121 [loFull,hiFull] = kcatBoundsLocal(kcat0);
    +0122 loLog = log(loFull(reps));
    +0123 hiLog = log(hiFull(reps));
    +0124 
    +0125 if isempty(popsize)
    +0126     popsize = 4 + floor(3*log(n));
    +0127 end
    +0128 popsize = max(4, round(popsize));
    +0129 
    +0130 expand = @(Xlog) exp(Xlog(assign,:));
    +0131 
    +0132 % Baseline: score the untouched prior, and pick up the excarbon-augmented
    +0133 % model to carry through the rest of the run (see evotuneScore's 4th
    +0134 % output -- avoids rescanning metabolite formulas on every candidate).
    +0135 [obj0,rmse0,~,baseModel] = scoreCandidate(ecModel,tunableIdx,ecRxnIdsTunable,evoData,modelAdapter,params,kcat0,kcat0,sigma0log);
    +0136 bestObj = obj0; bestRmse = rmse0; bestVec = kcat0;
    +0137 
    +0138 rmseTrace = []; objectiveTrace = [];
    +0139 
    +0140 [meanX,sigma,D,pSigma,pC,cs,ds,cc,c1,cmu,muEff,w,mu,chiN] = cmaesInit(x0,sig,popsize);
    +0141 
    +0142 if ~isempty(seed)
    +0143     rng(seed);
    +0144 end
    +0145 
    +0146 generation = 0;
    +0147 while generation < params.maxGenerations
    +0148     Z = randn(n,popsize);
    +0149     Xlog = meanX + sigma * (D .* Z);
    +0150     Xlog = min(max(Xlog,loLog),hiLog);
    +0151     % Recompute Z consistent with any clipping (D>0 throughout by construction).
    +0152     Z = (Xlog - meanX) ./ (sigma * D);
    +0153 
    +0154     kcatMatrix = expand(Xlog);
    +0155     objVals = zeros(popsize,1); rmseVals = zeros(popsize,1);
    +0156     if nProc == 1
    +0157         for k = 1:popsize
    +0158             [objVals(k),rmseVals(k),~,baseModel] = scoreCandidate( ...
    +0159                 baseModel,tunableIdx,ecRxnIdsTunable,evoData,modelAdapter,params, ...
    +0160                 kcatMatrix(:,k),kcat0,sigma0log);
    +0161         end
    +0162     else
    +0163         parfor k = 1:popsize
    +0164             [objVals(k),rmseVals(k)] = scoreCandidate( ...
    +0165                 ecModel,tunableIdx,ecRxnIdsTunable,evoData,modelAdapter,params, ...
    +0166                 kcatMatrix(:,k),kcat0,sigma0log);
    +0167         end
    +0168     end
    +0169     generation = generation + 1;
    +0170 
    +0171     [~,ord] = sort(objVals,'ascend');
    +0172     if objVals(ord(1)) < bestObj
    +0173         bestObj = objVals(ord(1));
    +0174         bestRmse = rmseVals(ord(1));
    +0175         bestVec = kcatMatrix(:,ord(1));
    +0176     end
    +0177     rmseTrace(end+1) = bestRmse; %#ok<AGROW>
    +0178     objectiveTrace(end+1) = bestObj; %#ok<AGROW>
    +0179     if verbose
    +0180         fprintf('generation %d: objective %.4f, rmse %.4f\n', generation, bestObj, bestRmse);
    +0181     end
    +0182     if bestRmse <= params.rmseThreshold
    +0183         break
    +0184     end
    +0185 
    +0186     [meanX,sigma,D,pSigma,pC] = cmaesUpdate( ...
    +0187         meanX,sigma,D,pSigma,pC,Z,ord,w,mu,cs,ds,cc,c1,cmu,muEff,chiN,generation);
    +0188 end
    +0189 
    +0190 ecModel.ec.kcat(tunableIdx) = bestVec;
    +0191 ecModel = applyKcatConstraints(ecModel,'updateRxns',ecRxnIdsTunable);
    +0192 
    +0193 result = struct();
    +0194 result.rxns            = ecRxnIdsTunable;
    +0195 result.oldKcat          = kcat0;
    +0196 result.newKcat          = bestVec;
    +0197 result.groups           = groups;
    +0198 result.rmseTrace        = rmseTrace;
    +0199 result.objectiveTrace   = objectiveTrace;
    +0200 result.nGenerations     = generation;
    +0201 result.converged        = bestRmse <= params.rmseThreshold;
    +0202 end
    +0203 
    +0204 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% Scoring core, shared with screenKcatLeverage/tunePriorPenaltyWeight.
    +0205 
    +0206 function [obj,rmse,rmseDetail,ecModel] = scoreCandidate(ecModel,tunableIdx,ecRxnIdsTunable,evoData,modelAdapter,params,kcatVec,kcat0,sigma0log)
    +0207 ecModel.ec.kcat(tunableIdx) = kcatVec;
    +0208 ecModel = applyKcatConstraints(ecModel,'updateRxns',ecRxnIdsTunable);
    +0209 [obj,rmse,rmseDetail,ecModel] = evotuneScore(ecModel,evoData, ...
    +0210     'modelAdapter',modelAdapter, 'maxGrowthWeight',params.maxGrowthWeight, ...
    +0211     'priorPenaltyWeight',params.priorPenaltyWeight, ...
    +0212     'kcatVec',kcatVec, 'kcat0',kcat0, 'sigma0log',sigma0log);
    +0213 end
    +0214 
    +0215 function [lo,hi] = kcatBoundsLocal(kcat0)
    +0216 % Biologically plausible bounds for proposed kcats, in 1/s. The window is
    +0217 % 1e-2 to 1e4 for an ordinary kcat, and always widened far enough to
    +0218 % contain the prior with a hundred-fold margin either side.
    +0219 lo = min(1e-2, kcat0/100);
    +0220 hi = max(1e4, kcat0*100);
    +0221 end
    +0222 
    +0223 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% Separable (diagonal) CMA-ES core.
    +0224 % Standard (mu/mu_w,lambda)-CMA-ES with a diagonal-only covariance update
    +0225 % (Ros & Hansen 2008), operating in log-kcat space. Sampling, ranking,
    +0226 % recombination, step-size (cumulative step-size adaptation) and
    +0227 % per-coordinate variance updates are the textbook equations; see e.g.
    +0228 % Hansen, "The CMA Evolution Strategy: A Tutorial".
    +0229 
    +0230 function [meanX,sigma,D,pSigma,pC,cs,ds,cc,c1,cmu,muEff,w,mu,chiN] = cmaesInit(x0,sig,popsize)
    +0231 n = numel(x0);
    +0232 mu = floor(popsize/2);
    +0233 wRaw = log(mu+0.5) - log((1:mu)');
    +0234 w = wRaw / sum(wRaw);
    +0235 muEff = 1 / sum(w.^2);
    +0236 
    +0237 cs  = (muEff+2) / (n+muEff+5);
    +0238 ds  = 1 + 2*max(0,sqrt((muEff-1)/(n+1))-1) + cs;
    +0239 cc  = (4+muEff/n) / (n+4+2*muEff/n);
    +0240 c1  = 2 / ((n+1.3)^2+muEff);
    +0241 cmu = min(1-c1, 2*(muEff-2+1/muEff) / ((n+2)^2+muEff));
    +0242 chiN = sqrt(n) * (1 - 1/(4*n) + 1/(21*n^2));
    +0243 
    +0244 meanX = x0;
    +0245 % Initial per-coordinate step scaled by each parameter's own prior sigma
    +0246 % (relative to the median), rather than uniform -- mirrors passing
    +0247 % scaling_of_variables to cma in the Python port.
    +0248 D = sig / median(sig);
    +0249 sigma = median(sig);
    +0250 pSigma = zeros(n,1);
    +0251 pC = zeros(n,1);
    +0252 end
    +0253 
    +0254 function [meanX,sigma,D,pSigma,pC] = cmaesUpdate( ...
    +0255     meanX,sigma,D,pSigma,pC,Z,ord,w,mu,cs,ds,cc,c1,cmu,muEff,chiN,generation)
    +0256 n = numel(meanX);
    +0257 Zbest = Z(:,ord(1:mu));
    +0258 zw = Zbest * w;
    +0259 
    +0260 meanX = meanX + sigma * (D .* zw);
    +0261 
    +0262 pSigma = (1-cs)*pSigma + sqrt(cs*(2-cs)*muEff) * zw;
    +0263 sigma = sigma * exp((cs/ds) * (norm(pSigma)/chiN - 1));
    +0264 
    +0265 hSigmaThresh = (1.4 + 2/(n+1)) * chiN;
    +0266 hSigma = (norm(pSigma) / sqrt(1-(1-cs)^(2*generation))) < hSigmaThresh;
    +0267 
    +0268 pC = (1-cc)*pC + hSigma * sqrt(cc*(2-cc)*muEff) * (D .* zw);
    +0269 
    +0270 Cdiag = D.^2;
    +0271 rankMuTerm = (D.*Zbest).^2 * w;
    +0272 Cdiag = (1-c1-cmu)*Cdiag + c1*(pC.^2 + (1-hSigma)*cc*(2-cc)*Cdiag) + cmu*rankMuTerm;
    +0273 Cdiag = max(Cdiag, 1e-300);
    +0274 D = sqrt(Cdiag);
    +0275 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/evotune/evotuneScore.html b/doc/src/kcat_tuning/evotune/evotuneScore.html new file mode 100644 index 00000000..1eaa0322 --- /dev/null +++ b/doc/src/kcat_tuning/evotune/evotuneScore.html @@ -0,0 +1,283 @@ + + + + Description of evotuneScore + + + + + + + + + +
    Home > src > kcat_tuning > evotune > evotuneScore.m
    + + + +

    evotuneScore +

    + +

    PURPOSE ^

    +
    evotuneScore Score one ecModel's current kcats against evotune data.
    + +

    SYNOPSIS ^

    +
    function [objective,rmse,rmseDetail,ecModel] = evotuneScore(ecModel,evoData,varargin)
    + +

    DESCRIPTION ^

    +
     evotuneScore  Score one ecModel's current kcats against evotune data.
    +
    + Internal helper used by cmaesKcatTuning, screenKcatLeverage and
    + tunePriorPenaltyWeight to score one ecModel (with a given set of kcats
    + already applied via applyKcatConstraints) against the experimental
    + growth and flux data. Fuses what geckopy splits into simulate.py (the
    + FBA half) and distance.py (the RMSE half) into one function.
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     ecModel with the current candidate kcats already applied (via
    +     applyKcatConstraints). Not mutated.
    + evoData : struct
    +     structure with experimental data to be used, as returned by
    +     loadEvotuneData.
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + maxGrowthWeight : double
    +     relative weight of the max-growth dataset against the flux dataset:
    +     (rmseFlux + w*rmseMaxGrate) / (w+1) (default 1.0).
    + priorPenaltyWeight : double
    +     weight on a prior term added to the objective (default 0, i.e. the
    +     objective equals the plain RMSE). See kcatVec/kcat0/sigma0log below.
    + kcatVec, kcat0, sigma0log : double
    +     only used when priorPenaltyWeight > 0: the tunable kcat subset's
    +     current values, prior values, and per-kcat prior log-space std dev,
    +     all the same length and in the same order. The penalty added to the
    +     objective is priorPenaltyWeight * mean((log(kcatVec./kcat0)./sigma0log).^2).
    +
    + Returns
    + -------
    + objective : double
    +     rmse, plus the prior penalty term when priorPenaltyWeight > 0. This
    +     is what a search should minimise.
    + rmse : double
    +     the plain (unpenalised) average RMSE, always comparable across runs
    +     regardless of priorPenaltyWeight.
    + rmseDetail : cell
    +     per-condition RMSE values, labelled by data type and condition index.
    + ecModel : struct
    +     the input ecModel, with ec.excarbon cached on it if it wasn't
    +     already present. MATLAB structs are copied on assignment, not
    +     shared by reference like a Python object, so callers scoring many
    +     candidates in a loop should carry this output back in as the base
    +     copy for the next candidate, rather than recomputing excarbon (an
    +     expensive metabolite-formula scan) on every single call.
    +
    + See also
    + --------
    + cmaesKcatTuning, screenKcatLeverage, loadEvotuneData
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • cmaesKcatTuning cmaesKcatTuning Tune kcats against experimental data with CMA-ES.
    • screenKcatLeverage screenKcatLeverage Report which kcats the data can actually speak to.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function [objective,rmse,rmseDetail,ecModel] = evotuneScore(ecModel,evoData,varargin)
    +0002 % evotuneScore  Score one ecModel's current kcats against evotune data.
    +0003 %
    +0004 % Internal helper used by cmaesKcatTuning, screenKcatLeverage and
    +0005 % tunePriorPenaltyWeight to score one ecModel (with a given set of kcats
    +0006 % already applied via applyKcatConstraints) against the experimental
    +0007 % growth and flux data. Fuses what geckopy splits into simulate.py (the
    +0008 % FBA half) and distance.py (the RMSE half) into one function.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % ecModel : struct
    +0013 %     ecModel with the current candidate kcats already applied (via
    +0014 %     applyKcatConstraints). Not mutated.
    +0015 % evoData : struct
    +0016 %     structure with experimental data to be used, as returned by
    +0017 %     loadEvotuneData.
    +0018 %
    +0019 % Name-Value Arguments
    +0020 % --------------------
    +0021 % modelAdapter : ModelAdapter
    +0022 %     a loaded model adapter (default: the current default model adapter).
    +0023 % maxGrowthWeight : double
    +0024 %     relative weight of the max-growth dataset against the flux dataset:
    +0025 %     (rmseFlux + w*rmseMaxGrate) / (w+1) (default 1.0).
    +0026 % priorPenaltyWeight : double
    +0027 %     weight on a prior term added to the objective (default 0, i.e. the
    +0028 %     objective equals the plain RMSE). See kcatVec/kcat0/sigma0log below.
    +0029 % kcatVec, kcat0, sigma0log : double
    +0030 %     only used when priorPenaltyWeight > 0: the tunable kcat subset's
    +0031 %     current values, prior values, and per-kcat prior log-space std dev,
    +0032 %     all the same length and in the same order. The penalty added to the
    +0033 %     objective is priorPenaltyWeight * mean((log(kcatVec./kcat0)./sigma0log).^2).
    +0034 %
    +0035 % Returns
    +0036 % -------
    +0037 % objective : double
    +0038 %     rmse, plus the prior penalty term when priorPenaltyWeight > 0. This
    +0039 %     is what a search should minimise.
    +0040 % rmse : double
    +0041 %     the plain (unpenalised) average RMSE, always comparable across runs
    +0042 %     regardless of priorPenaltyWeight.
    +0043 % rmseDetail : cell
    +0044 %     per-condition RMSE values, labelled by data type and condition index.
    +0045 % ecModel : struct
    +0046 %     the input ecModel, with ec.excarbon cached on it if it wasn't
    +0047 %     already present. MATLAB structs are copied on assignment, not
    +0048 %     shared by reference like a Python object, so callers scoring many
    +0049 %     candidates in a loop should carry this output back in as the base
    +0050 %     copy for the next candidate, rather than recomputing excarbon (an
    +0051 %     expensive metabolite-formula scan) on every single call.
    +0052 %
    +0053 % See also
    +0054 % --------
    +0055 % cmaesKcatTuning, screenKcatLeverage, loadEvotuneData
    +0056 
    +0057 p = parseGECKOargs(varargin, { ...
    +0058     'modelAdapter', []; ...
    +0059     'maxGrowthWeight', 1.0; ...
    +0060     'priorPenaltyWeight', 0.0; ...
    +0061     'kcatVec', []; ...
    +0062     'kcat0', []; ...
    +0063     'sigma0log', []});
    +0064 modelAdapter        = p.modelAdapter;
    +0065 maxGrowthWeight     = p.maxGrowthWeight;
    +0066 priorPenaltyWeight  = p.priorPenaltyWeight;
    +0067 
    +0068 if isempty(modelAdapter)
    +0069     modelAdapter = ModelAdapterManager.getDefault();
    +0070     if isempty(modelAdapter)
    +0071         error('Either send in a modelAdapter or set the default ecModel adapter in the ModelAdapterManager.')
    +0072     end
    +0073 end
    +0074 
    +0075 if ~isfield(ecModel,'excarbon')
    +0076     ecModel = fillCarbonNum(ecModel);
    +0077     ecModel.excarbon(ecModel.excarbon == 0) = 1;
    +0078 end
    +0079 
    +0080 rmse_1 = []; rmseDetail1 = []; rmse_2 = []; rmseDetail2 = [];
    +0081 
    +0082 if ~isempty(evoData.fluxData)
    +0083     [rmse_1, rmseDetail1] = simulateCondition(ecModel,evoData.fluxData,true,evoData.zeroFlux,modelAdapter);
    +0084     rmseDetail1 = [cellstr("fluxData_" + string(1:numel(rmseDetail1)))',num2cell(rmseDetail1)];
    +0085 end
    +0086 if ~isempty(evoData.maxGrate)
    +0087     [rmse_2, rmseDetail2] = simulateCondition(ecModel,evoData.maxGrate,false,evoData.zeroFlux,modelAdapter);
    +0088     rmseDetail2 = [cellstr("maxGrowth_" + string(1:numel(rmseDetail2)))',num2cell(rmseDetail2)];
    +0089 end
    +0090 
    +0091 parts = []; weights = [];
    +0092 if ~isempty(rmse_1)
    +0093     parts(end+1) = rmse_1; weights(end+1) = 1.0;
    +0094 end
    +0095 if ~isempty(rmse_2)
    +0096     parts(end+1) = rmse_2; weights(end+1) = maxGrowthWeight;
    +0097 end
    +0098 if isempty(parts)
    +0099     rmse = NaN;
    +0100 else
    +0101     rmse = sum(parts .* weights) / sum(weights);
    +0102 end
    +0103 rmseDetail = [rmseDetail1;rmseDetail2];
    +0104 
    +0105 objective = rmse;
    +0106 if priorPenaltyWeight > 0 && ~isempty(p.kcatVec) && ~isempty(p.kcat0) && ~isempty(p.sigma0log)
    +0107     dev = log(p.kcatVec(:) ./ p.kcat0(:)) ./ p.sigma0log(:);
    +0108     objective = rmse + priorPenaltyWeight * mean(dev.^2);
    +0109 end
    +0110 end
    +0111 
    +0112 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +0113 function [rmse, rmseList] = simulateCondition(ecModel,data,constrain,rxn2block,modelAdapter)
    +0114 % One condition's FBA simulation + carbon-weighted RMSE against measured
    +0115 % data.
    +0116 
    +0117 rmseList = zeros(length(data.conds),1);
    +0118 
    +0119 [~,exchIdx] = ismember(data.conds,data.exchMets);
    +0120 if any(exchIdx == 0)
    +0121     missingMets = strjoin(unique(data.conds(exchIdx == 0)), '; ');
    +0122     error('Carbon source(s) "%s" in the provided fluxData or maxGrowth cannot be matched by name with an exchange reaction.', missingMets);
    +0123 end
    +0124 
    +0125 for i = 1:length(data.conds)
    +0126     % Set all other carbon sources to zero, then unblock this condition's
    +0127     model_tmp = setParam(ecModel,'lb',data.exchRxnIDs(unique(exchIdx)),0);
    +0128     if constrain % RMSE from flux data: constrain carbon uptake at the measured rate
    +0129         model_tmp = setParam(model_tmp,'lb',data.exchRxnIDs(exchIdx(i)),data.exchFluxes(i,exchIdx(i)));
    +0130     else % RMSE from max growth: leave carbon uptake fully open
    +0131         model_tmp = setParam(model_tmp,'lb',data.exchRxnIDs(exchIdx(i)),-1000);
    +0132     end
    +0133 
    +0134     % This row's own carbon source is never itself asserted zero-flux.
    +0135     rxn2blockIter = rxn2block;
    +0136     rxn2blockIter(strcmp(rxn2blockIter,data.exchRxnIDs(exchIdx(i)))) = [];
    +0137 
    +0138     o2Flux = data.exchFluxes(i,strcmp('oxygen',data.exchMets));
    +0139     if o2Flux == 0
    +0140         model_tmp = modelAdapter.makeModelAnaerobic(model_tmp);
    +0141     end
    +0142     if ~(isnan(data.Ptot(i)) || data.Ptot(i) == 0)
    +0143         model_tmp = modelAdapter.changeProteinBiomass(model_tmp,data.Ptot(i));
    +0144     end
    +0145 
    +0146     sol = solveLP(model_tmp);
    +0147     if checkSolution(sol)
    +0148         bioRxn  = getIndexes(model_tmp,data.biomass,'rxns');
    +0149         % Biomass carries an assumed 41 Cmmol/gDCW, matching fillCarbonNum.
    +0150         bioMeas = data.grRate(i) * 41;
    +0151         bioSim  = sol.x(bioRxn) * 41;
    +0152 
    +0153         if constrain
    +0154             fluxToCheck   = ~isnan(data.exchFluxes(i,:));
    +0155             fluxRxnIdx    = getIndexes(model_tmp,data.exchRxnIDs(fluxToCheck),'rxns');
    +0156             cNormMeasFlux = model_tmp.excarbon(fluxRxnIdx) .* transpose(data.exchFluxes(i,fluxToCheck));
    +0157             cNormSimFlux  = model_tmp.excarbon(fluxRxnIdx) .* sol.x(fluxRxnIdx);
    +0158 
    +0159             blockRxnIdx = getIndexes(model_tmp,rxn2blockIter,'rxns');
    +0160             blockSim    = sol.x(blockRxnIdx) .* model_tmp.excarbon(blockRxnIdx);
    +0161             % Already-correct zero predictions don't dilute the RMSE.
    +0162             blockSim(blockSim == 0) = [];
    +0163             blockMeas = zeros(numel(blockSim),1);
    +0164 
    +0165             measured  = [cNormMeasFlux; bioMeas; blockMeas];
    +0166             simulated = [cNormSimFlux; bioSim; blockSim];
    +0167         else
    +0168             measured  = bioMeas;
    +0169             simulated = bioSim;
    +0170         end
    +0171         rmseList(i) = sqrt(mean((measured - simulated).^2));
    +0172     else
    +0173         rmseList(i) = NaN;
    +0174     end
    +0175 end
    +0176 rmseList(isnan(rmseList)) = 99; % Fixed penalty for an infeasible condition.
    +0177 if isfield(data,'evotuneRMSEweight') && ~isempty(data.evotuneRMSEweight)
    +0178     rmseList = rmseList .* data.evotuneRMSEweight;
    +0179 end
    +0180 rmse = mean(rmseList);
    +0181 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/evotune/index.html b/doc/src/kcat_tuning/evotune/index.html new file mode 100644 index 00000000..36e5aa4b --- /dev/null +++ b/doc/src/kcat_tuning/evotune/index.html @@ -0,0 +1,29 @@ + + + + Index for Directory src/kcat_tuning/evotune + + + + + + + + + + +
    < Master indexIndex for src/kcat_tuning/evotune >
    + +

    Index for src/kcat_tuning/evotune

    + +

    Matlab files in this directory:

    + +
     bestParsimoniousbestParsimonious The fewest-changes point whose RMSE is within
     cmaesKcatTuningcmaesKcatTuning Tune kcats against experimental data with CMA-ES.
     evotuneScoreevotuneScore Score one ecModel's current kcats against evotune data.
     isozymeTieMapisozymeTieMap Index of the parameter each isozyme copy follows.
     loadEvotuneDataloadEvotuneData Load experimental data for evotune (CMA-ES) kcat tuning.
     nChangednChanged How many kcats differ from their prior by more than relTol.
     parsimonyFrontierparsimonyFrontier Score kcat with progressively more of it reverted to
     resolveTunableContextresolveTunableContext The tunable kcat subset plus everything derived
     screenKcatLeveragescreenKcatLeverage Report which kcats the data can actually speak to.
     selectTunableMaskselectTunableMask Build a tunableMask from a screenKcatLeverage report.
     tunePriorPenaltyWeighttunePriorPenaltyWeight Sweep priorPenaltyWeight and report the
    + + + + +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/evotune/isozymeTieMap.html b/doc/src/kcat_tuning/evotune/isozymeTieMap.html new file mode 100644 index 00000000..89323f72 --- /dev/null +++ b/doc/src/kcat_tuning/evotune/isozymeTieMap.html @@ -0,0 +1,165 @@ + + + + Description of isozymeTieMap + + + + + + + + + +
    Home > src > kcat_tuning > evotune > isozymeTieMap.m
    + + + +

    isozymeTieMap +

    + +

    PURPOSE ^

    +
    isozymeTieMap Index of the parameter each isozyme copy follows.
    + +

    SYNOPSIS ^

    +
    function tieMap = isozymeTieMap(rxnIds,kcat0,varargin)
    + +

    DESCRIPTION ^

    +
     isozymeTieMap  Index of the parameter each isozyme copy follows.
    +
    + A reaction catalysed by several isozymes gets one ec.rxns row per
    + isozyme, each with its own kcat. Where the kcat assignment could tell
    + them apart, those are genuinely different parameters; where it could
    + not, every copy shares the same value from the same source, and an
    + untied search is then free to invent a difference between them that
    + means nothing biologically. Copies group together (and share one
    + parameter) when they share a base reaction (the part of the rxn id
    + before its "_EXP_" isozyme suffix), a prior value, and -- when sources
    + is given -- a source.
    +
    + Parameters
    + ----------
    + rxnIds : cell
    +     ec.rxns entries.
    + kcat0 : double
    +     prior kcat per row, same length as rxnIds.
    +
    + Name-Value Arguments
    + --------------------
    + sources : cell
    +     ec.source entries, same length as rxnIds (default: not used, so
    +     grouping ignores source).
    + relTol : double
    +     relative tolerance for treating two prior values as equal (default
    +     1e-9).
    +
    + Returns
    + -------
    + tieMap : double
    +     one entry per position. tieMap(i) == i for a free parameter,
    +     otherwise the (lower) index of the representative it follows.
    +
    + See also
    + --------
    + cmaesKcatTuning, screenKcatLeverage
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: + + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function tieMap = isozymeTieMap(rxnIds,kcat0,varargin)
    +0002 % isozymeTieMap  Index of the parameter each isozyme copy follows.
    +0003 %
    +0004 % A reaction catalysed by several isozymes gets one ec.rxns row per
    +0005 % isozyme, each with its own kcat. Where the kcat assignment could tell
    +0006 % them apart, those are genuinely different parameters; where it could
    +0007 % not, every copy shares the same value from the same source, and an
    +0008 % untied search is then free to invent a difference between them that
    +0009 % means nothing biologically. Copies group together (and share one
    +0010 % parameter) when they share a base reaction (the part of the rxn id
    +0011 % before its "_EXP_" isozyme suffix), a prior value, and -- when sources
    +0012 % is given -- a source.
    +0013 %
    +0014 % Parameters
    +0015 % ----------
    +0016 % rxnIds : cell
    +0017 %     ec.rxns entries.
    +0018 % kcat0 : double
    +0019 %     prior kcat per row, same length as rxnIds.
    +0020 %
    +0021 % Name-Value Arguments
    +0022 % --------------------
    +0023 % sources : cell
    +0024 %     ec.source entries, same length as rxnIds (default: not used, so
    +0025 %     grouping ignores source).
    +0026 % relTol : double
    +0027 %     relative tolerance for treating two prior values as equal (default
    +0028 %     1e-9).
    +0029 %
    +0030 % Returns
    +0031 % -------
    +0032 % tieMap : double
    +0033 %     one entry per position. tieMap(i) == i for a free parameter,
    +0034 %     otherwise the (lower) index of the representative it follows.
    +0035 %
    +0036 % See also
    +0037 % --------
    +0038 % cmaesKcatTuning, screenKcatLeverage
    +0039 p = parseGECKOargs(varargin, { ...
    +0040     'sources', []; ...
    +0041     'relTol', 1e-9});
    +0042 sources = p.sources;
    +0043 relTol  = p.relTol;
    +0044 
    +0045 n = numel(kcat0);
    +0046 if numel(rxnIds) ~= n
    +0047     error('rxnIds has %d entries; kcat0 has %d.', numel(rxnIds), n)
    +0048 end
    +0049 tieMap = (1:n)';
    +0050 
    +0051 keys = cell(n,1);
    +0052 for i = 1:n
    +0053     base = baseReaction(rxnIds{i});
    +0054     if kcat0(i) > 0
    +0055         logKey = sprintf('%d', round(log(kcat0(i)) / relTol));
    +0056     else
    +0057         logKey = 'NONE';
    +0058     end
    +0059     if isempty(sources)
    +0060         srcKey = '';
    +0061     else
    +0062         srcKey = char(sources{i});
    +0063     end
    +0064     keys{i} = strjoin({base, logKey, srcKey}, char(31));
    +0065 end
    +0066 
    +0067 [~, ~, groupIdx] = unique(keys);
    +0068 for g = 1:max(groupIdx)
    +0069     members = find(groupIdx == g);
    +0070     if numel(members) > 1
    +0071         tieMap(members) = members(1);
    +0072     end
    +0073 end
    +0074 end
    +0075 
    +0076 function base = baseReaction(rxnId)
    +0077 % The reaction an ec.rxns entry belongs to, isozyme suffix removed.
    +0078 parts = strsplit(rxnId, '_EXP_');
    +0079 base = parts{1};
    +0080 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/evotune/loadEvotuneData.html b/doc/src/kcat_tuning/evotune/loadEvotuneData.html new file mode 100644 index 00000000..97a7e2be --- /dev/null +++ b/doc/src/kcat_tuning/evotune/loadEvotuneData.html @@ -0,0 +1,144 @@ + + + + Description of loadEvotuneData + + + + + + + + + +
    Home > src > kcat_tuning > evotune > loadEvotuneData.m
    + + + +

    loadEvotuneData +

    + +

    PURPOSE ^

    +
    loadEvotuneData Load experimental data for evotune (CMA-ES) kcat tuning.
    + +

    SYNOPSIS ^

    +
    function evoData = loadEvotuneData(varargin)
    + +

    DESCRIPTION ^

    +
     loadEvotuneData  Load experimental data for evotune (CMA-ES) kcat tuning.
    +
    + Reads the three experimental data files used by cmaesKcatTuning from the
    + data subfolder of the model directory defined by the model adapter. Each
    + file is optional: a missing file yields [] (fluxData/maxGrate) or an
    + empty cell array (zeroFlux) rather than an error.
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + evoData : struct
    +     structure with the loaded experimental data.
    +
    + Notes
    + -----
    + The evoData structure has the following fields:
    +
    + - fluxData : flux data loaded from evotuneFluxData.tsv, with the biomass
    +   reaction id stored in fluxData.biomass. [] if that file isn't present.
    + - maxGrate : maximum growth-rate data loaded from evotuneMaxGrowth.tsv,
    +   with the biomass reaction id stored in maxGrate.biomass. [] if that
    +   file isn't present.
    + - zeroFlux : reaction IDs assumed to carry zero flux, loaded from
    +   evotuneZeroExch.tsv. Empty cell array if that file isn't present.
    +
    + See also
    + --------
    + cmaesKcatTuning, evotuneScore
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: + + + + + +

    SOURCE CODE ^

    +
    0001 function evoData = loadEvotuneData(varargin)
    +0002 % loadEvotuneData  Load experimental data for evotune (CMA-ES) kcat tuning.
    +0003 %
    +0004 % Reads the three experimental data files used by cmaesKcatTuning from the
    +0005 % data subfolder of the model directory defined by the model adapter. Each
    +0006 % file is optional: a missing file yields [] (fluxData/maxGrate) or an
    +0007 % empty cell array (zeroFlux) rather than an error.
    +0008 %
    +0009 % Name-Value Arguments
    +0010 % --------------------
    +0011 % modelAdapter : ModelAdapter
    +0012 %     a loaded model adapter (default: the current default model adapter).
    +0013 %
    +0014 % Returns
    +0015 % -------
    +0016 % evoData : struct
    +0017 %     structure with the loaded experimental data.
    +0018 %
    +0019 % Notes
    +0020 % -----
    +0021 % The evoData structure has the following fields:
    +0022 %
    +0023 % - fluxData : flux data loaded from evotuneFluxData.tsv, with the biomass
    +0024 %   reaction id stored in fluxData.biomass. [] if that file isn't present.
    +0025 % - maxGrate : maximum growth-rate data loaded from evotuneMaxGrowth.tsv,
    +0026 %   with the biomass reaction id stored in maxGrate.biomass. [] if that
    +0027 %   file isn't present.
    +0028 % - zeroFlux : reaction IDs assumed to carry zero flux, loaded from
    +0029 %   evotuneZeroExch.tsv. Empty cell array if that file isn't present.
    +0030 %
    +0031 % See also
    +0032 % --------
    +0033 % cmaesKcatTuning, evotuneScore
    +0034 p = parseGECKOargs(varargin, { ...
    +0035     'modelAdapter', []});
    +0036 modelAdapter = p.modelAdapter;
    +0037 
    +0038 if isempty(modelAdapter)
    +0039     modelAdapter = ModelAdapterManager.getDefault();
    +0040     if isempty(modelAdapter)
    +0041         error('Either send in a modelAdapter or set the default ecModel adapter in the ModelAdapterManager.')
    +0042     end
    +0043 end
    +0044 
    +0045 basePath = modelAdapter.params.path;
    +0046 
    +0047 evoData.fluxData = loadFluxData(fullfile(basePath,'data','evotuneFluxData.tsv'), modelAdapter);
    +0048 if ~isempty(evoData.fluxData)
    +0049     evoData.fluxData.biomass = modelAdapter.params.bioRxn;
    +0050 end
    +0051 
    +0052 evoData.maxGrate = loadFluxData(fullfile(basePath,'data','evotuneMaxGrowth.tsv'), modelAdapter);
    +0053 if ~isempty(evoData.maxGrate)
    +0054     evoData.maxGrate.biomass = modelAdapter.params.bioRxn;
    +0055 end
    +0056 
    +0057 % Unlike loadFluxData (used for fluxData/maxGrate above, which already
    +0058 % degrades to [] on a missing file), readtable has no such guard, so this
    +0059 % is wrapped explicitly to keep all three files uniformly optional.
    +0060 zeroExchFile = fullfile(basePath,'data','evotuneZeroExch.tsv');
    +0061 if isfile(zeroExchFile)
    +0062     evoData.zeroFlux = table2cell(readtable(zeroExchFile, 'Delimiter', '\t', 'FileType','delimitedtext'));
    +0063 else
    +0064     evoData.zeroFlux = {};
    +0065 end
    +0066 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/evotune/nChanged.html b/doc/src/kcat_tuning/evotune/nChanged.html new file mode 100644 index 00000000..b9058947 --- /dev/null +++ b/doc/src/kcat_tuning/evotune/nChanged.html @@ -0,0 +1,98 @@ + + + + Description of nChanged + + + + + + + + + +
    Home > src > kcat_tuning > evotune > nChanged.m
    + + + +

    nChanged +

    + +

    PURPOSE ^

    +
    nChanged How many kcats differ from their prior by more than relTol.
    + +

    SYNOPSIS ^

    +
    function n = nChanged(kcat,kcat0,varargin)
    + +

    DESCRIPTION ^

    +
     nChanged  How many kcats differ from their prior by more than relTol.
    +
    + The 2% default matches the threshold MATLAB's own per-source
    + "unchanged" reporting has historically used.
    +
    + Parameters
    + ----------
    + kcat, kcat0 : double
    +     tuned and prior kcat vectors, same length.
    +
    + Name-Value Arguments
    + --------------------
    + relTol : double
    +     default 0.02.
    +
    + Returns
    + -------
    + n : double
    +     count of entries where abs(log(kcat./kcat0)) > log1p(relTol).
    +
    + See also
    + --------
    + tunePriorPenaltyWeight, parsimonyFrontier
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: + + + + + +

    SOURCE CODE ^

    +
    0001 function n = nChanged(kcat,kcat0,varargin)
    +0002 % nChanged  How many kcats differ from their prior by more than relTol.
    +0003 %
    +0004 % The 2% default matches the threshold MATLAB's own per-source
    +0005 % "unchanged" reporting has historically used.
    +0006 %
    +0007 % Parameters
    +0008 % ----------
    +0009 % kcat, kcat0 : double
    +0010 %     tuned and prior kcat vectors, same length.
    +0011 %
    +0012 % Name-Value Arguments
    +0013 % --------------------
    +0014 % relTol : double
    +0015 %     default 0.02.
    +0016 %
    +0017 % Returns
    +0018 % -------
    +0019 % n : double
    +0020 %     count of entries where abs(log(kcat./kcat0)) > log1p(relTol).
    +0021 %
    +0022 % See also
    +0023 % --------
    +0024 % tunePriorPenaltyWeight, parsimonyFrontier
    +0025 p = parseGECKOargs(varargin, { ...
    +0026     'relTol', 0.02});
    +0027 relTol = p.relTol;
    +0028 n = sum(abs(log(kcat(:) ./ kcat0(:))) > log1p(relTol));
    +0029 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/evotune/parsimonyFrontier.html b/doc/src/kcat_tuning/evotune/parsimonyFrontier.html new file mode 100644 index 00000000..9add89f4 --- /dev/null +++ b/doc/src/kcat_tuning/evotune/parsimonyFrontier.html @@ -0,0 +1,163 @@ + + + + Description of parsimonyFrontier + + + + + + + + + +
    Home > src > kcat_tuning > evotune > parsimonyFrontier.m
    + + + +

    parsimonyFrontier +

    + +

    PURPOSE ^

    +
    parsimonyFrontier Score kcat with progressively more of it reverted to
    + +

    SYNOPSIS ^

    +
    function points = parsimonyFrontier(scoreFcn,kcat,kcat0,sigma0log,varargin)
    + +

    DESCRIPTION ^

    +
     parsimonyFrontier  Score kcat with progressively more of it reverted to
    + prior.
    +
    + A tuned kcat vector that fits well by rewriting every parameter is not
    + a useful answer: changes should be few, and concentrated in the
    + parameters least confident about. This sweeps a revert-threshold (in
    + units of each kcat's own prior sigma) and reports how RMSE trades off
    + against how many kcats stayed at their tuned value, so a sparser
    + result within noise of the best fit can be preferred over the raw
    + tuner output. See bestParsimonious to pick a point off this frontier.
    +
    + Parameters
    + ----------
    + scoreFcn : function_handle
    +     scores one kcat vector; called once per threshold. Build it against
    +     a specific ecModel/evoData, e.g.
    +         scoreFcn = @(vec) evotuneScoreVector(ecModel,tunableIdx, ...
    +             ecRxnIdsTunable,evoData,modelAdapter,params,vec);
    +     where evotuneScoreVector applies vec to ecModel.ec.kcat(tunableIdx),
    +     calls applyKcatConstraints, and returns evotuneScore's plain rmse.
    + kcat, kcat0, sigma0log : double
    +     tuned vector, prior vector, and per-kcat prior sigma, all the same
    +     length.
    +
    + Name-Value Arguments
    + --------------------
    + thresholds : double
    +     sigma cutoffs to sweep, ascending (default
    +     [0 1 2 3 4 6 8 10 15]). 0 reverts nothing, reproducing kcat's own
    +     score.
    +
    + Returns
    + -------
    + points : struct array
    +     one entry per threshold, in the order given: threshold, kcat (the
    +     partially-reverted vector), nChanged, meanDev (mean movement in
    +     sigma units), rmse.
    +
    + See also
    + --------
    + bestParsimonious, nChanged
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • nChanged nChanged How many kcats differ from their prior by more than relTol.
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function points = parsimonyFrontier(scoreFcn,kcat,kcat0,sigma0log,varargin)
    +0002 % parsimonyFrontier  Score kcat with progressively more of it reverted to
    +0003 % prior.
    +0004 %
    +0005 % A tuned kcat vector that fits well by rewriting every parameter is not
    +0006 % a useful answer: changes should be few, and concentrated in the
    +0007 % parameters least confident about. This sweeps a revert-threshold (in
    +0008 % units of each kcat's own prior sigma) and reports how RMSE trades off
    +0009 % against how many kcats stayed at their tuned value, so a sparser
    +0010 % result within noise of the best fit can be preferred over the raw
    +0011 % tuner output. See bestParsimonious to pick a point off this frontier.
    +0012 %
    +0013 % Parameters
    +0014 % ----------
    +0015 % scoreFcn : function_handle
    +0016 %     scores one kcat vector; called once per threshold. Build it against
    +0017 %     a specific ecModel/evoData, e.g.
    +0018 %         scoreFcn = @(vec) evotuneScoreVector(ecModel,tunableIdx, ...
    +0019 %             ecRxnIdsTunable,evoData,modelAdapter,params,vec);
    +0020 %     where evotuneScoreVector applies vec to ecModel.ec.kcat(tunableIdx),
    +0021 %     calls applyKcatConstraints, and returns evotuneScore's plain rmse.
    +0022 % kcat, kcat0, sigma0log : double
    +0023 %     tuned vector, prior vector, and per-kcat prior sigma, all the same
    +0024 %     length.
    +0025 %
    +0026 % Name-Value Arguments
    +0027 % --------------------
    +0028 % thresholds : double
    +0029 %     sigma cutoffs to sweep, ascending (default
    +0030 %     [0 1 2 3 4 6 8 10 15]). 0 reverts nothing, reproducing kcat's own
    +0031 %     score.
    +0032 %
    +0033 % Returns
    +0034 % -------
    +0035 % points : struct array
    +0036 %     one entry per threshold, in the order given: threshold, kcat (the
    +0037 %     partially-reverted vector), nChanged, meanDev (mean movement in
    +0038 %     sigma units), rmse.
    +0039 %
    +0040 % See also
    +0041 % --------
    +0042 % bestParsimonious, nChanged
    +0043 p = parseGECKOargs(varargin, { ...
    +0044     'thresholds', [0 1 2 3 4 6 8 10 15]});
    +0045 thresholds = p.thresholds;
    +0046 
    +0047 kcat0     = kcat0(:);
    +0048 sigma0log = sigma0log(:);
    +0049 kcat      = kcat(:);
    +0050 
    +0051 points = repmat(struct('threshold',[],'kcat',[],'nChanged',[],'meanDev',[],'rmse',[]), ...
    +0052     numel(thresholds), 1);
    +0053 for t = 1:numel(thresholds)
    +0054     thr = thresholds(t);
    +0055     vec = revertBelow(kcat,kcat0,sigma0log,thr);
    +0056     points(t).threshold = thr;
    +0057     points(t).kcat       = vec;
    +0058     points(t).nChanged   = nChanged(vec,kcat0);
    +0059     points(t).meanDev    = mean(movementInSigma(vec,kcat0,sigma0log));
    +0060     points(t).rmse       = scoreFcn(vec);
    +0061 end
    +0062 end
    +0063 
    +0064 function dev = movementInSigma(kcat,kcat0,sigma0log)
    +0065 % Per-kcat displacement from the prior, in prior standard deviations.
    +0066 dev = abs(log(kcat ./ kcat0)) ./ sigma0log;
    +0067 end
    +0068 
    +0069 function vec = revertBelow(kcat,kcat0,sigma0log,threshold)
    +0070 % Put every kcat that moved less than threshold sigma back on its prior.
    +0071 keep = movementInSigma(kcat,kcat0,sigma0log) >= threshold;
    +0072 vec = kcat0;
    +0073 vec(keep) = kcat(keep);
    +0074 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/evotune/resolveTunableContext.html b/doc/src/kcat_tuning/evotune/resolveTunableContext.html new file mode 100644 index 00000000..701fb372 --- /dev/null +++ b/doc/src/kcat_tuning/evotune/resolveTunableContext.html @@ -0,0 +1,144 @@ + + + + Description of resolveTunableContext + + + + + + + + + +
    Home > src > kcat_tuning > evotune > resolveTunableContext.m
    + + + +

    resolveTunableContext +

    + +

    PURPOSE ^

    +
    resolveTunableContext The tunable kcat subset plus everything derived
    + +

    SYNOPSIS ^

    +
    function [tunableIdx,ecRxnIdsTunable,kcat0,groups,sigma0log,tieMap] = resolveTunableContext(ecModel,params,tunableMask)
    + +

    DESCRIPTION ^

    +
     resolveTunableContext  The tunable kcat subset plus everything derived
    + from it: source-group trust tiers and isozyme tie groups.
    +
    + Shared by screenKcatLeverage and cmaesKcatTuning so a screen and the
    + tuning run it feeds are always looking at exactly the same parameters.
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     ecModel with a populated ec.kcat.
    + params : struct
    +     modelAdapter.params.evotune (kcatSources, sigma0logSource,
    +     sigma0logDefault, tieIsozymes).
    + tunableMask : logical
    +     same length as ecModel.ec.rxns; [] to consider every kcat > 0.
    +
    + Returns
    + -------
    + tunableIdx : double
    +     indices into ecModel.ec.rxns/ec.kcat of the tunable subset.
    + ecRxnIdsTunable : cell
    + kcat0 : double
    + groups : cell
    +     source-group name per tunable row ('unlabelled' if unmatched).
    + sigma0log : double
    +     per-row prior std dev in log-space.
    + tieMap : double
    +     isozymeTieMap(ecRxnIdsTunable,kcat0,'sources',groups) if
    +     params.tieIsozymes, otherwise every row is its own free parameter.
    +
    + See also
    + --------
    + screenKcatLeverage, cmaesKcatTuning, isozymeTieMap
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • isozymeTieMap isozymeTieMap Index of the parameter each isozyme copy follows.
    +This function is called by: +
      +
    • cmaesKcatTuning cmaesKcatTuning Tune kcats against experimental data with CMA-ES.
    • screenKcatLeverage screenKcatLeverage Report which kcats the data can actually speak to.
    + + + + +

    SOURCE CODE ^

    +
    0001 function [tunableIdx,ecRxnIdsTunable,kcat0,groups,sigma0log,tieMap] = resolveTunableContext(ecModel,params,tunableMask)
    +0002 % resolveTunableContext  The tunable kcat subset plus everything derived
    +0003 % from it: source-group trust tiers and isozyme tie groups.
    +0004 %
    +0005 % Shared by screenKcatLeverage and cmaesKcatTuning so a screen and the
    +0006 % tuning run it feeds are always looking at exactly the same parameters.
    +0007 %
    +0008 % Parameters
    +0009 % ----------
    +0010 % ecModel : struct
    +0011 %     ecModel with a populated ec.kcat.
    +0012 % params : struct
    +0013 %     modelAdapter.params.evotune (kcatSources, sigma0logSource,
    +0014 %     sigma0logDefault, tieIsozymes).
    +0015 % tunableMask : logical
    +0016 %     same length as ecModel.ec.rxns; [] to consider every kcat > 0.
    +0017 %
    +0018 % Returns
    +0019 % -------
    +0020 % tunableIdx : double
    +0021 %     indices into ecModel.ec.rxns/ec.kcat of the tunable subset.
    +0022 % ecRxnIdsTunable : cell
    +0023 % kcat0 : double
    +0024 % groups : cell
    +0025 %     source-group name per tunable row ('unlabelled' if unmatched).
    +0026 % sigma0log : double
    +0027 %     per-row prior std dev in log-space.
    +0028 % tieMap : double
    +0029 %     isozymeTieMap(ecRxnIdsTunable,kcat0,'sources',groups) if
    +0030 %     params.tieIsozymes, otherwise every row is its own free parameter.
    +0031 %
    +0032 % See also
    +0033 % --------
    +0034 % screenKcatLeverage, cmaesKcatTuning, isozymeTieMap
    +0035 isTunable = ecModel.ec.kcat > 0;
    +0036 if ~isempty(tunableMask)
    +0037     isTunable = isTunable & tunableMask(:);
    +0038 end
    +0039 tunableIdx = find(isTunable);
    +0040 if isempty(tunableIdx)
    +0041     if isempty(tunableMask)
    +0042         error('No tunable kcats: ecModel.ec.kcat is all <= 0.')
    +0043     else
    +0044         error('No tunable kcats: ecModel.ec.kcat is all <= 0, or tunableMask excludes every one with a kcat.')
    +0045     end
    +0046 end
    +0047 
    +0048 ecRxnIdsTunable = ecModel.ec.rxns(tunableIdx);
    +0049 kcat0           = ecModel.ec.kcat(tunableIdx);
    +0050 sources         = ecModel.ec.source(tunableIdx);
    +0051 
    +0052 groups    = repmat({'unlabelled'}, numel(tunableIdx), 1);
    +0053 sigma0log = params.sigma0logDefault * ones(numel(tunableIdx),1);
    +0054 for i = 1:numel(params.kcatSources)
    +0055     idx = strcmpi(sources, params.kcatSources{i});
    +0056     groups(idx)    = params.kcatSources(i);
    +0057     sigma0log(idx) = params.sigma0logSource(i);
    +0058 end
    +0059 
    +0060 if isfield(params,'tieIsozymes') && params.tieIsozymes
    +0061     tieMap = isozymeTieMap(ecRxnIdsTunable, kcat0, 'sources', groups);
    +0062 else
    +0063     tieMap = (1:numel(kcat0))';
    +0064 end
    +0065 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/evotune/screenKcatLeverage.html b/doc/src/kcat_tuning/evotune/screenKcatLeverage.html new file mode 100644 index 00000000..005602ad --- /dev/null +++ b/doc/src/kcat_tuning/evotune/screenKcatLeverage.html @@ -0,0 +1,246 @@ + + + + Description of screenKcatLeverage + + + + + + + + + +
    Home > src > kcat_tuning > evotune > screenKcatLeverage.m
    + + + +

    screenKcatLeverage +

    + +

    PURPOSE ^

    +
    screenKcatLeverage Report which kcats the data can actually speak to.
    + +

    SYNOPSIS ^

    +
    function screen = screenKcatLeverage(ecModel,varargin)
    + +

    DESCRIPTION ^

    +
     screenKcatLeverage  Report which kcats the data can actually speak to.
    +
    + No optimisation happens here -- this only says which parameters are
    + worth curating or tuning, and can be read on its own well before any
    + tuning run. Each tie-group (isozyme copies sharing a prior and a source
    + move together when params.tieIsozymes) is perturbed up and down by
    + fold, and its leverage is the largest resulting change in RMSE. Groups
    + are ranked by that leverage weighted by sigma0log: a trusted source
    + needs proportionally more measured effect to rank alongside an
    + untrusted one.
    +
    + Costs one simulation per condition per tie-group probed (two probes
    + each, up and down) plus one baseline -- comparable in scale to a full
    + tuning run's evaluation budget, not a cheap pre-check.
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     ecModel with a populated ec.kcat.
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + evoData : struct
    +     as returned by loadEvotuneData (default: loaded from modelAdapter).
    + tunableMask : logical
    +     restrict which kcats are screened (default: every ec.kcat > 0).
    + fold : double
    +     fold-change used to perturb each tie-group up and down (default 2.0).
    + nProc : double
    +     number of parallel workers used to score candidate vectors (default
    +     1, i.e. serial). Requires Parallel Computing Toolbox for > 1.
    +
    + Returns
    + -------
    + screen : table
    +     one row per tie-group, sorted by rank descending: rxnId (the
    +     group's representative), nIsozymes, sourceGroup, kcat0, leverage,
    +     sigma0log, rank (leverage*sigma0log), cumLeverageShare (running
    +     total of rank as a fraction of its sum), and positions (a cell
    +     array of indices into ecModel.ec.rxns) -- what selectTunableMask
    +     needs to expand a row back into a mask.
    +
    + See also
    + --------
    + selectTunableMask, cmaesKcatTuning
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • evotuneScore evotuneScore Score one ecModel's current kcats against evotune data.
    • loadEvotuneData loadEvotuneData Load experimental data for evotune (CMA-ES) kcat tuning.
    • resolveTunableContext resolveTunableContext The tunable kcat subset plus everything derived
    +This function is called by: + + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function screen = screenKcatLeverage(ecModel,varargin)
    +0002 % screenKcatLeverage  Report which kcats the data can actually speak to.
    +0003 %
    +0004 % No optimisation happens here -- this only says which parameters are
    +0005 % worth curating or tuning, and can be read on its own well before any
    +0006 % tuning run. Each tie-group (isozyme copies sharing a prior and a source
    +0007 % move together when params.tieIsozymes) is perturbed up and down by
    +0008 % fold, and its leverage is the largest resulting change in RMSE. Groups
    +0009 % are ranked by that leverage weighted by sigma0log: a trusted source
    +0010 % needs proportionally more measured effect to rank alongside an
    +0011 % untrusted one.
    +0012 %
    +0013 % Costs one simulation per condition per tie-group probed (two probes
    +0014 % each, up and down) plus one baseline -- comparable in scale to a full
    +0015 % tuning run's evaluation budget, not a cheap pre-check.
    +0016 %
    +0017 % Parameters
    +0018 % ----------
    +0019 % ecModel : struct
    +0020 %     ecModel with a populated ec.kcat.
    +0021 %
    +0022 % Name-Value Arguments
    +0023 % --------------------
    +0024 % modelAdapter : ModelAdapter
    +0025 %     a loaded model adapter (default: the current default model adapter).
    +0026 % evoData : struct
    +0027 %     as returned by loadEvotuneData (default: loaded from modelAdapter).
    +0028 % tunableMask : logical
    +0029 %     restrict which kcats are screened (default: every ec.kcat > 0).
    +0030 % fold : double
    +0031 %     fold-change used to perturb each tie-group up and down (default 2.0).
    +0032 % nProc : double
    +0033 %     number of parallel workers used to score candidate vectors (default
    +0034 %     1, i.e. serial). Requires Parallel Computing Toolbox for > 1.
    +0035 %
    +0036 % Returns
    +0037 % -------
    +0038 % screen : table
    +0039 %     one row per tie-group, sorted by rank descending: rxnId (the
    +0040 %     group's representative), nIsozymes, sourceGroup, kcat0, leverage,
    +0041 %     sigma0log, rank (leverage*sigma0log), cumLeverageShare (running
    +0042 %     total of rank as a fraction of its sum), and positions (a cell
    +0043 %     array of indices into ecModel.ec.rxns) -- what selectTunableMask
    +0044 %     needs to expand a row back into a mask.
    +0045 %
    +0046 % See also
    +0047 % --------
    +0048 % selectTunableMask, cmaesKcatTuning
    +0049 p = parseGECKOargs(varargin, { ...
    +0050     'modelAdapter', []; ...
    +0051     'evoData', []; ...
    +0052     'tunableMask', []; ...
    +0053     'fold', 2.0; ...
    +0054     'nProc', 1});
    +0055 modelAdapter = p.modelAdapter;
    +0056 evoData      = p.evoData;
    +0057 tunableMask  = p.tunableMask;
    +0058 fold         = p.fold;
    +0059 nProc        = max(1, round(p.nProc));
    +0060 
    +0061 if isempty(modelAdapter)
    +0062     modelAdapter = ModelAdapterManager.getDefault();
    +0063     if isempty(modelAdapter)
    +0064         error('Either send in a modelAdapter or set the default ecModel adapter in the ModelAdapterManager.')
    +0065     end
    +0066 end
    +0067 params = modelAdapter.params.evotune;
    +0068 if isempty(evoData)
    +0069     evoData = loadEvotuneData('modelAdapter', modelAdapter);
    +0070 end
    +0071 
    +0072 [tunableIdx,ecRxnIdsTunable,kcat0,groups,sigma0log,tieMap] = ...
    +0073     resolveTunableContext(ecModel,params,tunableMask);
    +0074 
    +0075 reps = find(tieMap == (1:numel(tieMap))');
    +0076 nReps = numel(reps);
    +0077 membersOf = cell(nReps,1);
    +0078 for r = 1:nReps
    +0079     membersOf{r} = find(tieMap == reps(r));
    +0080 end
    +0081 
    +0082 vectors = cell(1 + 2*nReps, 1);
    +0083 vectors{1} = kcat0;
    +0084 for r = 1:nReps
    +0085     members = membersOf{r};
    +0086     up = kcat0; up(members) = up(members) * fold;
    +0087     dn = kcat0; dn(members) = dn(members) / fold;
    +0088     vectors{1 + 2*r - 1} = up;
    +0089     vectors{1 + 2*r}     = dn;
    +0090 end
    +0091 nVec = numel(vectors);
    +0092 rmses = zeros(nVec,1);
    +0093 
    +0094 if nProc == 1
    +0095     % Serial path: carry the excarbon-augmented model from one call into
    +0096     % the next, so the metabolite-formula scan behind it (evotuneScore's
    +0097     % 4th output) runs once for the whole screen rather than once per
    +0098     % probe vector.
    +0099     baseModel = ecModel;
    +0100     for v = 1:nVec
    +0101         [~,rmses(v),~,baseModel] = scoreVector(baseModel,tunableIdx,ecRxnIdsTunable,evoData,modelAdapter,params,vectors{v});
    +0102     end
    +0103 else
    +0104     parfor v = 1:nVec
    +0105         [~,rmses(v)] = scoreVector(ecModel,tunableIdx,ecRxnIdsTunable,evoData,modelAdapter,params,vectors{v});
    +0106     end
    +0107 end
    +0108 
    +0109 baseRmse = rmses(1);
    +0110 rxnId       = cell(nReps,1);
    +0111 nIsozymes   = zeros(nReps,1);
    +0112 sourceGroup = cell(nReps,1);
    +0113 kcat0Col    = zeros(nReps,1);
    +0114 leverage    = zeros(nReps,1);
    +0115 sigma0logCol= zeros(nReps,1);
    +0116 positions   = cell(nReps,1);
    +0117 for r = 1:nReps
    +0118     upRmse = rmses(1 + 2*r - 1);
    +0119     dnRmse = rmses(1 + 2*r);
    +0120     members = membersOf{r};
    +0121     rxnId{r}        = ecRxnIdsTunable{reps(r)};
    +0122     nIsozymes(r)     = numel(members);
    +0123     sourceGroup{r}   = groups{reps(r)};
    +0124     kcat0Col(r)      = kcat0(reps(r));
    +0125     leverage(r)      = max(abs(upRmse - baseRmse), abs(dnRmse - baseRmse));
    +0126     sigma0logCol(r)  = sigma0log(reps(r));
    +0127     positions{r}     = tunableIdx(members);
    +0128 end
    +0129 
    +0130 rnk = leverage .* sigma0logCol;
    +0131 [~,ord] = sort(rnk,'descend');
    +0132 rxnId=rxnId(ord); nIsozymes=nIsozymes(ord); sourceGroup=sourceGroup(ord);
    +0133 kcat0Col=kcat0Col(ord); leverage=leverage(ord); sigma0logCol=sigma0logCol(ord);
    +0134 positions=positions(ord); rnk=rnk(ord);
    +0135 
    +0136 total = sum(rnk);
    +0137 if total > 0
    +0138     cumLeverageShare = cumsum(rnk) / total;
    +0139 else
    +0140     cumLeverageShare = zeros(size(rnk));
    +0141 end
    +0142 
    +0143 screen = table(rxnId,nIsozymes,sourceGroup,kcat0Col,leverage,sigma0logCol,rnk,cumLeverageShare,positions, ...
    +0144     'VariableNames',{'rxnId','nIsozymes','sourceGroup','kcat0','leverage','sigma0log','rank','cumLeverageShare','positions'});
    +0145 end
    +0146 
    +0147 function [obj,rmse,rmseDetail,ecModel] = scoreVector(ecModel,tunableIdx,ecRxnIdsTunable,evoData,modelAdapter,params,kcatVec)
    +0148 ecModel.ec.kcat(tunableIdx) = kcatVec;
    +0149 ecModel = applyKcatConstraints(ecModel,'updateRxns',ecRxnIdsTunable);
    +0150 [obj,rmse,rmseDetail,ecModel] = evotuneScore(ecModel,evoData,'modelAdapter',modelAdapter,'maxGrowthWeight',params.maxGrowthWeight);
    +0151 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/evotune/selectTunableMask.html b/doc/src/kcat_tuning/evotune/selectTunableMask.html new file mode 100644 index 00000000..1d88a18a --- /dev/null +++ b/doc/src/kcat_tuning/evotune/selectTunableMask.html @@ -0,0 +1,123 @@ + + + + Description of selectTunableMask + + + + + + + + + +
    Home > src > kcat_tuning > evotune > selectTunableMask.m
    + + + +

    selectTunableMask +

    + +

    PURPOSE ^

    +
    selectTunableMask Build a tunableMask from a screenKcatLeverage report.
    + +

    SYNOPSIS ^

    +
    function mask = selectTunableMask(ecModel,screen,varargin)
    + +

    DESCRIPTION ^

    +
     selectTunableMask  Build a tunableMask from a screenKcatLeverage report.
    +
    + Keeps the fewest highest-ranked groups whose combined leverage reaches
    + targetImpactShare of the total -- a relative cutoff, so the same
    + targetImpactShare selects a comparable quality of parameter set on any
    + model, rather than an absolute leverage value or a fixed count
    + calibrated on a different model's scale.
    +
    + Pure and cheap -- no simulation, only screen is read.
    +
    + Parameters
    + ----------
    + ecModel : struct
    + screen : table
    +     as returned by screenKcatLeverage.
    +
    + Name-Value Arguments
    + --------------------
    + targetImpactShare : double
    +     default 0.9. Not a validated universal constant -- check the
    +     resulting mask's size against screenKcatLeverage's own curve before
    +     trusting it on a new model.
    +
    + Returns
    + -------
    + mask : logical
    +     length numel(ecModel.ec.rxns).
    +
    + See also
    + --------
    + screenKcatLeverage, cmaesKcatTuning
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: + + + + + +

    SOURCE CODE ^

    +
    0001 function mask = selectTunableMask(ecModel,screen,varargin)
    +0002 % selectTunableMask  Build a tunableMask from a screenKcatLeverage report.
    +0003 %
    +0004 % Keeps the fewest highest-ranked groups whose combined leverage reaches
    +0005 % targetImpactShare of the total -- a relative cutoff, so the same
    +0006 % targetImpactShare selects a comparable quality of parameter set on any
    +0007 % model, rather than an absolute leverage value or a fixed count
    +0008 % calibrated on a different model's scale.
    +0009 %
    +0010 % Pure and cheap -- no simulation, only screen is read.
    +0011 %
    +0012 % Parameters
    +0013 % ----------
    +0014 % ecModel : struct
    +0015 % screen : table
    +0016 %     as returned by screenKcatLeverage.
    +0017 %
    +0018 % Name-Value Arguments
    +0019 % --------------------
    +0020 % targetImpactShare : double
    +0021 %     default 0.9. Not a validated universal constant -- check the
    +0022 %     resulting mask's size against screenKcatLeverage's own curve before
    +0023 %     trusting it on a new model.
    +0024 %
    +0025 % Returns
    +0026 % -------
    +0027 % mask : logical
    +0028 %     length numel(ecModel.ec.rxns).
    +0029 %
    +0030 % See also
    +0031 % --------
    +0032 % screenKcatLeverage, cmaesKcatTuning
    +0033 p = parseGECKOargs(varargin, { ...
    +0034     'targetImpactShare', 0.9});
    +0035 targetImpactShare = p.targetImpactShare;
    +0036 
    +0037 mask = false(numel(ecModel.ec.rxns),1);
    +0038 if isempty(screen) || height(screen) == 0
    +0039     return
    +0040 end
    +0041 prevCum = [0; screen.cumLeverageShare(1:end-1)];
    +0042 keep = prevCum < targetImpactShare;
    +0043 for i = find(keep)'
    +0044     mask(screen.positions{i}) = true;
    +0045 end
    +0046 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/evotune/tunePriorPenaltyWeight.html b/doc/src/kcat_tuning/evotune/tunePriorPenaltyWeight.html new file mode 100644 index 00000000..f729d55e --- /dev/null +++ b/doc/src/kcat_tuning/evotune/tunePriorPenaltyWeight.html @@ -0,0 +1,299 @@ + + + + Description of tunePriorPenaltyWeight + + + + + + + + + +
    Home > src > kcat_tuning > evotune > tunePriorPenaltyWeight.m
    + + + +

    tunePriorPenaltyWeight +

    + +

    PURPOSE ^

    +
    tunePriorPenaltyWeight Sweep priorPenaltyWeight and report the
    + +

    SYNOPSIS ^

    +
    function sweepTable = tunePriorPenaltyWeight(ecModel,varargin)
    + +

    DESCRIPTION ^

    +
     tunePriorPenaltyWeight  Sweep priorPenaltyWeight and report the
    + fit/reproducibility trade-off, so the value doesn't have to be picked
    + blind.
    +
    + priorPenaltyWeight charges for moving a kcat away from its prior, and
    + mainly exists to keep large corrections reproducible across seeds
    + rather than landing on an arbitrary point along a flat direction. How
    + strong a charge is enough is model- and data-specific: too little and
    + the search's largest corrections disagree across seeds; too much and
    + the search stops finding real corrections at all. This runs
    + cmaesKcatTuning at every value in candidates, each at every seed in
    + seeds, all against the same tunable set, and reports both fit and
    + cross-seed reproducibility per value.
    +
    + This is exactly as expensive as it sounds: numel(candidates)*numel(seeds)
    + full cmaesKcatTuning runs, none of them reusable across candidates. Pass
    + a screen you already have to at least avoid recomputing that part.
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     ecModel with a populated ec.kcat. Not mutated (MATLAB structs are
    +     copied on assignment; every candidate/seed pair starts fresh from
    +     this input regardless of what earlier runs did).
    +
    + Name-Value Arguments
    + --------------------
    + modelAdapter, evoData, tunableMask, screen, targetImpactShare, popsize,
    + nProc, verbose
    +     as in cmaesKcatTuning.
    + candidates : double
    +     priorPenaltyWeight values to try (default [0.0, 0.01, 0.03, 0.1]).
    + seeds : double
    +     seeds to run each candidate at (default [0, 1]). Reproducibility
    +     columns pool every pair of seeds, so more than two sharpens them
    +     but costs proportionally more.
    + foldThreshold : double
    +     a kcat counts as "moved" past this fold change from its prior
    +     (default 2.0). Matches nChanged's convention loosely (a different
    +     quantity, same spirit).
    +
    + Returns
    + -------
    + sweepTable : table
    +     one row per candidate: priorPenaltyWeight, nSeeds, distanceMean,
    +     distanceSpread (max minus min across seeds), nChangedMean,
    +     nMovers (kcats past foldThreshold in either seed of a pair, summed
    +     over every pair), nBothMoved (past it in both), pctDirectionAgree,
    +     medianFoldSpread and maxFoldSpread (among movers, the largest
    +     fold-change between what two seeds landed on), and fitCost
    +     (distanceMean relative to the best candidate's, as a fraction).
    +
    + See also
    + --------
    + cmaesKcatTuning, screenKcatLeverage, selectTunableMask, nChanged
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • cmaesKcatTuning cmaesKcatTuning Tune kcats against experimental data with CMA-ES.
    • loadEvotuneData loadEvotuneData Load experimental data for evotune (CMA-ES) kcat tuning.
    • nChanged nChanged How many kcats differ from their prior by more than relTol.
    • screenKcatLeverage screenKcatLeverage Report which kcats the data can actually speak to.
    • selectTunableMask selectTunableMask Build a tunableMask from a screenKcatLeverage report.
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function sweepTable = tunePriorPenaltyWeight(ecModel,varargin)
    +0002 % tunePriorPenaltyWeight  Sweep priorPenaltyWeight and report the
    +0003 % fit/reproducibility trade-off, so the value doesn't have to be picked
    +0004 % blind.
    +0005 %
    +0006 % priorPenaltyWeight charges for moving a kcat away from its prior, and
    +0007 % mainly exists to keep large corrections reproducible across seeds
    +0008 % rather than landing on an arbitrary point along a flat direction. How
    +0009 % strong a charge is enough is model- and data-specific: too little and
    +0010 % the search's largest corrections disagree across seeds; too much and
    +0011 % the search stops finding real corrections at all. This runs
    +0012 % cmaesKcatTuning at every value in candidates, each at every seed in
    +0013 % seeds, all against the same tunable set, and reports both fit and
    +0014 % cross-seed reproducibility per value.
    +0015 %
    +0016 % This is exactly as expensive as it sounds: numel(candidates)*numel(seeds)
    +0017 % full cmaesKcatTuning runs, none of them reusable across candidates. Pass
    +0018 % a screen you already have to at least avoid recomputing that part.
    +0019 %
    +0020 % Parameters
    +0021 % ----------
    +0022 % ecModel : struct
    +0023 %     ecModel with a populated ec.kcat. Not mutated (MATLAB structs are
    +0024 %     copied on assignment; every candidate/seed pair starts fresh from
    +0025 %     this input regardless of what earlier runs did).
    +0026 %
    +0027 % Name-Value Arguments
    +0028 % --------------------
    +0029 % modelAdapter, evoData, tunableMask, screen, targetImpactShare, popsize,
    +0030 % nProc, verbose
    +0031 %     as in cmaesKcatTuning.
    +0032 % candidates : double
    +0033 %     priorPenaltyWeight values to try (default [0.0, 0.01, 0.03, 0.1]).
    +0034 % seeds : double
    +0035 %     seeds to run each candidate at (default [0, 1]). Reproducibility
    +0036 %     columns pool every pair of seeds, so more than two sharpens them
    +0037 %     but costs proportionally more.
    +0038 % foldThreshold : double
    +0039 %     a kcat counts as "moved" past this fold change from its prior
    +0040 %     (default 2.0). Matches nChanged's convention loosely (a different
    +0041 %     quantity, same spirit).
    +0042 %
    +0043 % Returns
    +0044 % -------
    +0045 % sweepTable : table
    +0046 %     one row per candidate: priorPenaltyWeight, nSeeds, distanceMean,
    +0047 %     distanceSpread (max minus min across seeds), nChangedMean,
    +0048 %     nMovers (kcats past foldThreshold in either seed of a pair, summed
    +0049 %     over every pair), nBothMoved (past it in both), pctDirectionAgree,
    +0050 %     medianFoldSpread and maxFoldSpread (among movers, the largest
    +0051 %     fold-change between what two seeds landed on), and fitCost
    +0052 %     (distanceMean relative to the best candidate's, as a fraction).
    +0053 %
    +0054 % See also
    +0055 % --------
    +0056 % cmaesKcatTuning, screenKcatLeverage, selectTunableMask, nChanged
    +0057 p = parseGECKOargs(varargin, { ...
    +0058     'modelAdapter', []; ...
    +0059     'evoData', []; ...
    +0060     'tunableMask', []; ...
    +0061     'screen', []; ...
    +0062     'targetImpactShare', 0.9; ...
    +0063     'popsize', []; ...
    +0064     'nProc', 1; ...
    +0065     'verbose', true; ...
    +0066     'candidates', [0.0, 0.01, 0.03, 0.1]; ...
    +0067     'seeds', [0, 1]; ...
    +0068     'foldThreshold', 2.0});
    +0069 modelAdapter      = p.modelAdapter;
    +0070 evoData           = p.evoData;
    +0071 tunableMask       = p.tunableMask;
    +0072 screen            = p.screen;
    +0073 targetImpactShare = p.targetImpactShare;
    +0074 popsize           = p.popsize;
    +0075 nProc             = p.nProc;
    +0076 verbose           = p.verbose;
    +0077 candidates        = p.candidates;
    +0078 seeds             = p.seeds;
    +0079 foldThreshold     = p.foldThreshold;
    +0080 
    +0081 if isempty(modelAdapter)
    +0082     modelAdapter = ModelAdapterManager.getDefault();
    +0083     if isempty(modelAdapter)
    +0084         error('Either send in a modelAdapter or set the default ecModel adapter in the ModelAdapterManager.')
    +0085     end
    +0086 end
    +0087 if isempty(evoData)
    +0088     evoData = loadEvotuneData('modelAdapter', modelAdapter);
    +0089 end
    +0090 if isempty(tunableMask)
    +0091     if isempty(screen)
    +0092         screen = screenKcatLeverage(ecModel, 'modelAdapter',modelAdapter, ...
    +0093             'evoData',evoData, 'nProc',nProc);
    +0094     end
    +0095     tunableMask = selectTunableMask(ecModel, screen, 'targetImpactShare',targetImpactShare);
    +0096 end
    +0097 
    +0098 nCand = numel(candidates);
    +0099 priorPenaltyWeight = zeros(nCand,1);
    +0100 nSeeds             = zeros(nCand,1);
    +0101 distanceMean        = zeros(nCand,1);
    +0102 distanceSpread       = zeros(nCand,1);
    +0103 nChangedMean        = zeros(nCand,1);
    +0104 nMovers              = zeros(nCand,1);
    +0105 nBothMoved           = zeros(nCand,1);
    +0106 pctDirectionAgree   = zeros(nCand,1);
    +0107 medianFoldSpread    = zeros(nCand,1);
    +0108 maxFoldSpread        = zeros(nCand,1);
    +0109 
    +0110 for c = 1:nCand
    +0111     lam = candidates(c);
    +0112     lamParams = modelAdapter.params.evotune;
    +0113     lamParams.priorPenaltyWeight = lam;
    +0114 
    +0115     vectors = cell(numel(seeds),1);
    +0116     distances = zeros(numel(seeds),1);
    +0117     changed = zeros(numel(seeds),1);
    +0118     oldKcat = [];
    +0119     for s = 1:numel(seeds)
    +0120         seedVal = seeds(s);
    +0121         adapterCopy = modelAdapter;
    +0122         adapterCopy.params.evotune = lamParams;
    +0123         [~,res] = cmaesKcatTuning(ecModel, 'modelAdapter',adapterCopy, ...
    +0124             'evoData',evoData, 'tunableMask',tunableMask, ...
    +0125             'popsize',popsize, 'nProc',nProc, 'seed',seedVal, 'verbose',verbose);
    +0126         vectors{s} = res.newKcat;
    +0127         if ~isempty(res.rmseTrace)
    +0128             distances(s) = res.rmseTrace(end);
    +0129         else
    +0130             distances(s) = NaN;
    +0131         end
    +0132         changed(s) = nChanged(res.newKcat, res.oldKcat);
    +0133         oldKcat = res.oldKcat;
    +0134         if verbose
    +0135             fprintf('priorPenaltyWeight=%g seed=%d: distance %.4f, %d changed\n', ...
    +0136                 lam, seedVal, distances(s), changed(s));
    +0137         end
    +0138     end
    +0139 
    +0140     movers = 0; both = 0; agree = 0; spreads = [];
    +0141     for i = 1:numel(vectors)
    +0142         for j = (i+1):numel(vectors)
    +0143             fa = foldChangeLocal(vectors{i}, oldKcat);
    +0144             fb = foldChangeLocal(vectors{j}, oldKcat);
    +0145             moversIJ = (fa > foldThreshold) | (fb > foldThreshold);
    +0146             bothIJ   = (fa > foldThreshold) & (fb > foldThreshold);
    +0147             agreeIJ  = sign(log(vectors{i}(bothIJ) ./ oldKcat(bothIJ))) == ...
    +0148                        sign(log(vectors{j}(bothIJ) ./ oldKcat(bothIJ)));
    +0149             movers = movers + sum(moversIJ);
    +0150             both   = both + sum(bothIJ);
    +0151             agree  = agree + sum(agreeIJ);
    +0152             if any(moversIJ)
    +0153                 ratio = vectors{i}(moversIJ) ./ vectors{j}(moversIJ);
    +0154                 spreads = [spreads; max(ratio, 1./ratio)]; %#ok<AGROW>
    +0155             end
    +0156         end
    +0157     end
    +0158 
    +0159     priorPenaltyWeight(c) = lam;
    +0160     nSeeds(c)              = numel(seeds);
    +0161     distanceMean(c)        = mean(distances);
    +0162     if numel(distances) > 1
    +0163         distanceSpread(c) = max(distances) - min(distances);
    +0164     else
    +0165         distanceSpread(c) = 0;
    +0166     end
    +0167     nChangedMean(c) = mean(changed);
    +0168     nMovers(c)      = movers;
    +0169     nBothMoved(c)   = both;
    +0170     if both > 0
    +0171         pctDirectionAgree(c) = agree / both;
    +0172     else
    +0173         pctDirectionAgree(c) = NaN;
    +0174     end
    +0175     if ~isempty(spreads)
    +0176         medianFoldSpread(c) = median(spreads);
    +0177         maxFoldSpread(c)    = max(spreads);
    +0178     else
    +0179         medianFoldSpread(c) = NaN;
    +0180         maxFoldSpread(c)    = NaN;
    +0181     end
    +0182 end
    +0183 
    +0184 fitCost = distanceMean / min(distanceMean) - 1.0;
    +0185 
    +0186 sweepTable = table(priorPenaltyWeight,nSeeds,distanceMean,distanceSpread,nChangedMean, ...
    +0187     nMovers,nBothMoved,pctDirectionAgree,medianFoldSpread,maxFoldSpread,fitCost);
    +0188 end
    +0189 
    +0190 function f = foldChangeLocal(kcat,kcat0)
    +0191 % Per-kcat fold change from the prior, always >= 1. The only caller of
    +0192 % this in the whole port is this file, so it stays local rather than
    +0193 % getting its own file (see nChanged.m for the parsimony function that
    +0194 % genuinely is needed from two places).
    +0195 f = exp(abs(log(kcat(:) ./ kcat0(:))));
    +0196 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/fillCarbonNum.html b/doc/src/kcat_tuning/fillCarbonNum.html new file mode 100644 index 00000000..74806a2f --- /dev/null +++ b/doc/src/kcat_tuning/fillCarbonNum.html @@ -0,0 +1,368 @@ + + + + Description of fillCarbonNum + + + + + + + + + +
    Home > src > kcat_tuning > fillCarbonNum.m
    + + + +

    fillCarbonNum +

    + +

    PURPOSE ^

    +
    + +

    SYNOPSIS ^

    +
    This is a script file.
    + +

    DESCRIPTION ^

    +
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: + +This function is called by: + + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function model = fillCarbonNum(model)
    +0002 % fillCarbonNum  Add a carbon number field to the model.
    +0003 %
    +0004 % Adds a model.excarbon field with the carbon number of each exchange
    +0005 % reaction, used to weight the RMSE during evotune kcat tuning.
    +0006 %
    +0007 % Parameters
    +0008 % ----------
    +0009 % model : struct
    +0010 %     ecModel that was generated by makeEcModel, or loaded from an earlier
    +0011 %     run. Not compatible with ecModels generated by earlier GECKO versions
    +0012 %     (pre 3.0).
    +0013 %
    +0014 % Returns
    +0015 % -------
    +0016 % model : struct
    +0017 %     ecModel with an added model.excarbon field.
    +0018 
    +0019 % get carbonnum for each exchange rxn to further calculation of error
    +0020 model.excarbon = zeros(length(model.rxns),1);
    +0021 [EXrxn, EXrxnIdx] = getExchangeRxns(model);
    +0022 [CarbonNum,EXfors] = getcarbonnum(model,EXrxn);
    +0023 model.excarbon(EXrxnIdx) = CarbonNum;
    +0024 model.excarbon(strcmp(model.rxnNames,'growth')) = 41;
    +0025 
    +0026 function [CarbonNum,EXfors,changedmets] = getcarbonnum(model,exrxn)
    +0027 % getcarbonnum  Get carbon numbers matching the model.
    +0028 %
    +0029 % Parameters
    +0030 % ----------
    +0031 % model : struct
    +0032 %     ecModel that was generated by makeEcModel, or loaded from an earlier
    +0033 %     run. Not compatible with ecModels generated by earlier GECKO versions
    +0034 %     (pre 3.0).
    +0035 % exrxn : cell
    +0036 %     exchange reactions to use for counting.
    +0037 %
    +0038 % Returns
    +0039 % -------
    +0040 % CarbonNum : double
    +0041 %     carbon number for each exchange reaction.
    +0042 % EXfors : cell
    +0043 %     formulae of the exchanged metabolites.
    +0044 % changedmets : cell
    +0045 %     exchange reactions whose carbon number could not be determined.
    +0046 %
    +0047 
    +0048 % exrxn must be an exchange rxn and only contain one mets in the equation
    +0049 [~,idx] = ismember(exrxn,model.rxns);
    +0050 EXmets = model.S(:,idx);
    +0051 % find all exchange mets
    +0052 EXmetsIdx = zeros(length(exrxn),1);
    +0053 for k = 1:length(EXmets(1,:))
    +0054     EXmetsIdx(k) = find(EXmets(:,k)); %
    +0055 end
    +0056 EXfors = model.metFormulas(EXmetsIdx);
    +0057 [Ematrix, elements] = getElementalComposition(EXfors,{'C'});
    +0058 Ematrix = Ematrix(:,1);
    +0059 changedmets = exrxn(isnan(Ematrix));
    +0060 Ematrix(isnan(Ematrix)) = 1;
    +0061 CarbonNum = Ematrix;
    +0062 
    +0063 function [Ematrix, elements] = getElementalComposition(formulae, elements, chargeInFormula)
    +0064 % Get the complete elemental composition matrix. It supports formulae with
    +0065 % generic elements, parentheses and decimal places
    +0066 %
    +0067 % USAGE:
    +0068 %    [Ematrix, elements] = getElementalComposition(formulae, elements, chargeInFormula)
    +0069 %
    +0070 % INPUT:
    +0071 %    formulae:        cell array of strings of chemical formulae. Can contain any generic elements starting
    +0072 %                     with a capital letter followed by lowercase letters or '_', followed by a non-negative number.
    +0073 %                     Also support '()', '[]', '{}'. E.g. {'H2O'; '[H2O]2(CuSO4)Generic_element0.5'}
    +0074 % OPTIONAL INPUTS:
    +0075 %    elements:        elements from previous call to preserve the order (default {})
    +0076 %    chargeInFormula: true to accept formulae containing the generic element 'Charge' representing the charges,
    +0077 %                     followed by a real number, e.g., 'HCharge1', 'SO4Charge-2' (default false).
    +0078 %
    +0079 % OUTPUTS:
    +0080 %    Ematrix:         elemental composition matrix (#formulae x #elements)
    +0081 %    elements:         cell array of elements corresponding to the columns of Ematrix
    +0082 %
    +0083 % E.g., [Ematrix, elements] = getElementalComposition({'H2O'; '[H2O]2(CuSO4)Generic_element0.5'}) would return:
    +0084 %  elements = {'H', 'O', 'Cu', 'S', 'Generic_element'}
    +0085 %  Ematrix = [ 2,   1,    0,   0,   0;
    +0086 %              4,   6,    1,   1,   0.5]
    +0087 %
    +0088 % Siu Hung Joshua Chan May 2017
    +0089 
    +0090 if nargin < 3 || isempty(chargeInFormula)
    +0091     chargeInFormula = false;
    +0092 else
    +0093     chargeInFormula = logical(chargeInFormula);
    +0094 end
    +0095 % for recalling the original formula at the top level if there are parentheses
    +0096 % in the formula leading to iterative calling
    +0097 persistent formTopLv
    +0098 persistent formCurLv
    +0099 % for storing error message during iterative calling
    +0100 persistent errMsg
    +0101 persistent errMsgInThisLoop
    +0102 persistent topLvJ
    +0103 persistent selfCall
    +0104 if isempty(selfCall)
    +0105     selfCall = 0;
    +0106 end
    +0107 if ~selfCall
    +0108     [formTopLv, errMsg] = deal('');
    +0109 end
    +0110 
    +0111 if ~isstruct(formulae)
    +0112     if ~iscell(formulae)
    +0113         % make sure it is a cell array of strings
    +0114         formulae = {formulae};
    +0115     end
    +0116 else
    +0117     % also accept COBRA model as input
    +0118     if isfield(formulae, 'metFormulas')
    +0119         formulae = formulae.metFormulas;
    +0120     else
    +0121         error('The 1st input ''formulae'' should be a cell array of strings of formulae or a COBRA model with *.metFormulas')
    +0122     end
    +0123 end
    +0124 
    +0125 if nargin < 2 || isempty(elements)
    +0126     elements = {};
    +0127 elseif numel(unique(elements)) < numel(elements)
    +0128     error('Repeated elements in the input ''elements'' array.')
    +0129 else
    +0130     elements = elements(:)';  % make sure it is a row vector
    +0131 end
    +0132 
    +0133 % the Ematrix
    +0134 Ematrix = zeros(numel(formulae), numel(elements));
    +0135 % replace all brackets and braces by parentheses
    +0136 formulae = regexprep(formulae, '[\[\{]', '\(');
    +0137 formulae = regexprep(formulae, '[\]\}]', '\)');
    +0138 digit = floor(log10(numel(formulae))) + 1;
    +0139 for j = 1:numel(formulae)
    +0140     if ~selfCall
    +0141         % reset top level information for each formula
    +0142         [formTopLv, topLvJ, errMsgInThisLoop] = deal(formulae{j}, j, false);
    +0143     end
    +0144     formulae{j} = strtrim(formulae{j});
    +0145     if ~isempty(formulae{j})
    +0146         % get all outer parentheses
    +0147         parenthesis = [];
    +0148         stP = [];
    +0149         stPpos = [];
    +0150         lv = 0;
    +0151         k = 1;
    +0152         while k <= length(formulae{j})
    +0153             if strcmp(formulae{j}(k),'(')
    +0154                 if lv == 0
    +0155                     pStart = k;
    +0156                 end
    +0157                 lv = lv + 1;
    +0158             elseif strcmp(formulae{j}(k),')')
    +0159                 if lv == 1
    +0160                     parenthesis = [parenthesis; [pStart k]];
    +0161                     % right parenthesis, get the following stoichiometry if any
    +0162                     stPre = regexp(formulae{j}(k+1:end), '^(\+|\-)?\d*\.?\d*', 'match');
    +0163                     if isempty(stPre)
    +0164                         stP = [stP; 1];
    +0165                         stPpos = [stPpos; k k];
    +0166                     else
    +0167                         stCheck = str2double(stPre{1});
    +0168                         s = '';
    +0169                         if isnan(stCheck)
    +0170                             s = 'Invalid';
    +0171                         elseif stCheck < 0
    +0172                             s = 'Negative';
    +0173                         end
    +0174                         if ~isempty(s)  % error if not convertible to number or negative
    +0175                             f = [formulae{j}(parenthesis(end,1):parenthesis(end,2)), stPre{1}];
    +0176                             addErrorMessage(sprintf('    %s stoichiometry in ''%s''\n', s, f))
    +0177                         end
    +0178                         % stoichiometry
    +0179                         stP = [stP; stCheck];
    +0180                         % position of the stoichiometry in the text
    +0181                         stPpos = [stPpos; k + 1, k + length(stPre{1})];
    +0182                         k = k + length(stPre{1});
    +0183                     end
    +0184                 end
    +0185                 lv = lv - 1;
    +0186             end
    +0187             k = k + 1;
    +0188         end
    +0189         if isempty(parenthesis)
    +0190         % No parenthesis, parse the formula
    +0191             re = regexp(formulae{j}, '([A-Z][a-z_]*)((?:\+|\-)?\d*\.?\d*)', 'tokens');
    +0192             s = strjoin(cellfun(@(x) strjoin(x,''), re, 'UniformOutput', false), '');
    +0193             errorFlag = 0;
    +0194             if ~strcmp(s, formulae{j})  % check if the entire formula is retrieved
    +0195                 errorFlag = 1;
    +0196             else
    +0197                 % check the stoichiometry
    +0198                 eleCheck = cellfun(@(x) x{1}, re, 'UniformOutput', false);
    +0199                 stCheck = cellfun(@(x) str2double(x{2}), re);
    +0200                 stCheck(cellfun(@(x) isempty(x{2}), re)) = 1;  % empty value => stoichiometry = 1
    +0201                 if any(isnan(stCheck))
    +0202                     f = strjoin(cellfun(@(x) strjoin(x, ''), re(isnan(stCheck)), 'UniformOutput', false), ''', ''');
    +0203                     [errorFlag, errMsgKey] = deal(2, 'Invalid');
    +0204                 else
    +0205                     % if chargeInFormula is true, detect negative stoich for non-charge elements, else any negative stoich
    +0206                     negSt = (~chargeInFormula | ~strcmp(eleCheck, 'Charge')) & stCheck < 0;
    +0207                     if any(negSt)
    +0208                         f = strjoin(cellfun(@(x) strjoin(x, ''), re(negSt), 'UniformOutput', false), ''', ''');
    +0209                         [errorFlag, errMsgKey] = deal(2, 'Negative');
    +0210                     end
    +0211                 end
    +0212             end
    +0213             if errorFlag > 0
    +0214                 if selfCall <= 1
    +0215                     s2 = sprintf('from the part ''%s''', formulae{j});
    +0216                 elseif selfCall == 2
    +0217                     s2 = sprintf('from the part ''(%s)''', formCurLv);
    +0218                 elseif selfCall == 3
    +0219                     s2 = sprintf('from the part ''(%s)''', formulae{j});
    +0220                 end
    +0221                 if errorFlag == 1
    +0222                     s2 = sprintf(['    Only ''%s'' can be recognized %s.\n'...
    +0223                         '       Each element should start with a capital letter followed by lower case letters'...
    +0224                         ' or ''_'' with indefinite length and followed by a number.\n'], s, s2);
    +0225                 elseif errorFlag == 2
    +0226                     s2 = sprintf('    %s stoichiometry in ''%s'' %s\n', errMsgKey, f, s2);
    +0227                 end
    +0228                 addErrorMessage(s2);
    +0229             end
    +0230             elementJ = repmat({''}, 1, numel(re));
    +0231             nEj = 0;
    +0232             stoichJ = zeros(numel(re),1);
    +0233             for k = 1:numel(re)
    +0234                 [ynK,idK] = ismember(re{k}(1), elementJ(1:nEj));
    +0235                 if ynK
    +0236                     k2 = idK;
    +0237                 else
    +0238                     nEj = nEj + 1;
    +0239                     elementJ{nEj} = re{k}{1};
    +0240                     k2 = nEj;
    +0241                 end
    +0242                 if isempty(re{k}{2})
    +0243                     stoichJ(k2) = stoichJ(k2) + 1;
    +0244                 else
    +0245                     stoichJ(k2) = stoichJ(k2) + str2double(re{k}{2});
    +0246                 end
    +0247             end
    +0248             elementJ = elementJ(1:nEj);
    +0249             stoichJ = stoichJ(1:nEj);
    +0250             [ynE, idE] = ismember(elementJ, elements);  % map to existing elements
    +0251             if any(~ynE)
    +0252                 idE(~ynE) = (numel(elements) + 1):(numel(elements) + sum(~ynE));
    +0253                 Ematrix(:, (numel(elements) + 1):(numel(elements) + sum(~ynE))) = 0;
    +0254                 elements = [elements, elementJ(~ynE)];
    +0255             end
    +0256             Ematrix(j, idE) = stoichJ;
    +0257         else
    +0258             % parentheses found. Iteratively get the formula inside parentheses
    +0259             rest = true(length(formulae{j}),1);
    +0260             for k = 1:size(parenthesis,1)
    +0261                 selfCallCur = selfCall;
    +0262                 selfCall = 3;
    +0263                 [EmatrixK, elements] = getElementalComposition(formulae{j}(...
    +0264                     (parenthesis(k,1)+1):(parenthesis(k,2)-1)), elements, chargeInFormula);
    +0265                 if numel(elements) > size(Ematrix, 2)
    +0266                     Ematrix(:, (size(Ematrix, 2) + 1):numel(elements)) = 0;
    +0267                 end
    +0268                 selfCall = selfCallCur;
    +0269                 Ematrix(j, 1:numel(elements)) = Ematrix(j, 1:numel(elements)) + EmatrixK * stP(k);
    +0270                 rest(parenthesis(k,1):stPpos(k,2)) = false;          
    +0271             end
    +0272             if any(rest)
    +0273                 formCurLv = formulae{j};
    +0274                 selfCallCur = selfCall;
    +0275                 selfCall = 1 + (selfCall >= 1);
    +0276                 while any(rest)
    +0277                     % get the consecutive part of the formula that is not in parentheses
    +0278                     [pStart, pEnd] = deal(find(rest, 1), find(~rest));
    +0279                     pEnd = min(pEnd(pEnd > pStart));
    +0280                     if isempty(pEnd)
    +0281                         pEnd = numel(rest);
    +0282                     else
    +0283                         pEnd = pEnd - 1;
    +0284                     end
    +0285                     [EmatrixK, elements] = getElementalComposition(formulae{j}(pStart:pEnd), elements, chargeInFormula);
    +0286                     if numel(elements) > size(Ematrix, 2)
    +0287                         Ematrix(:, (size(Ematrix, 2) + 1):numel(elements)) = 0;
    +0288                     end
    +0289                     Ematrix(j, 1:numel(elements)) = Ematrix(j, 1:numel(elements)) + EmatrixK;
    +0290                     rest(pStart:pEnd) = false;
    +0291                 end
    +0292                 selfCall = selfCallCur;
    +0293             end
    +0294         end
    +0295     else
    +0296         Ematrix(j,:) = NaN;
    +0297     end
    +0298 end
    +0299 Ematrix = Ematrix(:, 1:numel(elements));
    +0300 if ~selfCall 
    +0301     selfCall = [];
    +0302     if ~isempty(errMsg)
    +0303         error(['%s\n', errMsg], 'Invalid formula input:')
    +0304     end
    +0305 end
    +0306 
    +0307 % nested function for adding error messages
    +0308     function addErrorMessage(s)
    +0309         if ~errMsgInThisLoop
    +0310             errMsg = [errMsg, sprintf(['#%0' num2str(digit) 'd:  %s\n'], topLvJ, formTopLv)];
    +0311             errMsgInThisLoop = true;
    +0312         end
    +0313         errMsg = [errMsg, s];
    +0314     end
    +0315 end
    +0316 
    +0317 end
    +0318 
    +0319 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/index.html b/doc/src/kcat_tuning/index.html new file mode 100644 index 00000000..726a4d99 --- /dev/null +++ b/doc/src/kcat_tuning/index.html @@ -0,0 +1,31 @@ + + + + Index for Directory src/kcat_tuning + + + + + + + + + + +
    < Master indexIndex for src/kcat_tuning >
    + +

    Index for src/kcat_tuning

    + +

    Matlab files in this directory:

    + +
     fillCarbonNum
     sensitivityTuningsensitivityTuning Relax the most limiting kcats to reach a growth rate.
     sigmaFittersigmaFitter Fit the average enzyme saturation factor of an ecModel.
     truncateValuestruncateValues Round values in selected columns to six significant digits.
    + + +

    Subsequent directories:

    + + +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/sensitivityTuning.html b/doc/src/kcat_tuning/sensitivityTuning.html new file mode 100644 index 00000000..0af02957 --- /dev/null +++ b/doc/src/kcat_tuning/sensitivityTuning.html @@ -0,0 +1,315 @@ + + + + Description of sensitivityTuning + + + + + + + + + +
    Home > src > kcat_tuning > sensitivityTuning.m
    + + + +

    sensitivityTuning +

    + +

    PURPOSE ^

    +
    sensitivityTuning Relax the most limiting kcats to reach a growth rate.
    + +

    SYNOPSIS ^

    +
    function [model, tunedKcats] = sensitivityTuning(model, varargin)
    + +

    DESCRIPTION ^

    +
     sensitivityTuning  Relax the most limiting kcats to reach a growth rate.
    +
    + Iteratively increases the kcat of whichever enzyme currently limits growth
    + the most, until the model reaches the desired growth rate, updating the
    + tuned values in model.ec.kcat. The loop also stops, with a warning, when an
    + iteration raises growth by less than 1e-9.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + desiredGrowthRate : double
    +     kcats will be relaxed until this growth rate is reached (default: the
    +     experimental growth rate params.gR_exp from the model adapter).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + foldChange : double
    +     kcat values will be increased by this fold-change (default 10).
    + protToIgnore : cell
    +     vector of protein ids to be ignored in tuned kcats, e.g. {'P38122',
    +     'Q99271'} (default []).
    + verbose : logical
    +     whether progress should be reported (default true).
    +
    + Returns
    + -------
    + model : struct
    +     ecModel with updated model.ec.kcat.
    + tunedKcats : struct
    +     structure with information on tuned kcat values.
    +
    + Notes
    + -----
    + The tunedKcats structure has the following fields:
    +
    + - rxns : identifiers of reactions with tuned kcat values.
    + - rxnNames : names of the reactions in tunedKcats.rxns.
    + - enzymes : enzymes that catalyze the reactions in tunedKcats.rxns, whose
    +   kcat value has been tuned.
    + - oldKcat : kcat values in the input model.
    + - newKcat : kcat values in the output model, after tuning.
    + - source : source label of each kcat, taken from the input model before
    +   tuning.
    +
    + The model.ec.notes field will contain the original kcat value and source,
    + unless the kcat has previously been set by sensitivityTuning, in which case
    + the notes field remains unchanged.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     [model, tunedKcats] = sensitivityTuning(model);
    +     [model, tunedKcats] = sensitivityTuning(model, 'foldChange', 10);
    +     [model, tunedKcats] = sensitivityTuning(model, desiredGrowthRate, modelAdapter, foldChange, protToIgnore, verbose);
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function [model, tunedKcats] = sensitivityTuning(model, varargin)
    +0002 % sensitivityTuning  Relax the most limiting kcats to reach a growth rate.
    +0003 %
    +0004 % Iteratively increases the kcat of whichever enzyme currently limits growth
    +0005 % the most, until the model reaches the desired growth rate, updating the
    +0006 % tuned values in model.ec.kcat. The loop also stops, with a warning, when an
    +0007 % iteration raises growth by less than 1e-9.
    +0008 %
    +0009 % Parameters
    +0010 % ----------
    +0011 % model : struct
    +0012 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0013 %
    +0014 % Name-Value Arguments
    +0015 % --------------------
    +0016 % desiredGrowthRate : double
    +0017 %     kcats will be relaxed until this growth rate is reached (default: the
    +0018 %     experimental growth rate params.gR_exp from the model adapter).
    +0019 % modelAdapter : ModelAdapter
    +0020 %     a loaded model adapter (default: the current default model adapter).
    +0021 % foldChange : double
    +0022 %     kcat values will be increased by this fold-change (default 10).
    +0023 % protToIgnore : cell
    +0024 %     vector of protein ids to be ignored in tuned kcats, e.g. {'P38122',
    +0025 %     'Q99271'} (default []).
    +0026 % verbose : logical
    +0027 %     whether progress should be reported (default true).
    +0028 %
    +0029 % Returns
    +0030 % -------
    +0031 % model : struct
    +0032 %     ecModel with updated model.ec.kcat.
    +0033 % tunedKcats : struct
    +0034 %     structure with information on tuned kcat values.
    +0035 %
    +0036 % Notes
    +0037 % -----
    +0038 % The tunedKcats structure has the following fields:
    +0039 %
    +0040 % - rxns : identifiers of reactions with tuned kcat values.
    +0041 % - rxnNames : names of the reactions in tunedKcats.rxns.
    +0042 % - enzymes : enzymes that catalyze the reactions in tunedKcats.rxns, whose
    +0043 %   kcat value has been tuned.
    +0044 % - oldKcat : kcat values in the input model.
    +0045 % - newKcat : kcat values in the output model, after tuning.
    +0046 % - source : source label of each kcat, taken from the input model before
    +0047 %   tuning.
    +0048 %
    +0049 % The model.ec.notes field will contain the original kcat value and source,
    +0050 % unless the kcat has previously been set by sensitivityTuning, in which case
    +0051 % the notes field remains unchanged.
    +0052 %
    +0053 % Examples
    +0054 % --------
    +0055 %     % optional arguments may be given positionally or as name-value pairs:
    +0056 %     [model, tunedKcats] = sensitivityTuning(model);
    +0057 %     [model, tunedKcats] = sensitivityTuning(model, 'foldChange', 10);
    +0058 %     [model, tunedKcats] = sensitivityTuning(model, desiredGrowthRate, modelAdapter, foldChange, protToIgnore, verbose);
    +0059 
    +0060 p = parseGECKOargs(varargin, { ...
    +0061     'desiredGrowthRate', []; ...
    +0062     'modelAdapter',      []; ...
    +0063     'foldChange',        10; ...
    +0064     'protToIgnore',      {}; ...
    +0065     'verbose',           true});
    +0066 desiredGrowthRate = p.desiredGrowthRate;
    +0067 modelAdapter      = p.modelAdapter;
    +0068 foldChange        = p.foldChange;
    +0069 protToIgnore      = p.protToIgnore;
    +0070 verbose           = p.verbose;
    +0071 
    +0072 if isempty(modelAdapter)
    +0073     modelAdapter = ModelAdapterManager.getDefault();
    +0074     if isempty(modelAdapter)
    +0075         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0076     end
    +0077 end
    +0078 params = modelAdapter.params;
    +0079 if isempty(desiredGrowthRate)
    +0080     desiredGrowthRate = params.gR_exp;
    +0081 end
    +0082 
    +0083 kcatList = [];
    +0084 m = model;
    +0085 m.c = double(strcmp(m.rxns, params.bioRxn));% Make sure that growth is maximized
    +0086 
    +0087 [res,hs] = solveLP(m);
    +0088 if isempty(res.x)
    +0089     error('FBA of input model gives no valid result. Reduce protein pool constraint with setProtPoolSize and/or check if exchange constraints are correctly defined.')
    +0090 end
    +0091 % The loop stops when growth rises by less than growthStallTol over the
    +0092 % previous iteration (the first iteration has nothing to compare with).
    +0093 lastGrowth = NaN;
    +0094 growthStallTol = 1e-9;
    +0095 if ~m.ec.geckoLight
    +0096     %for the full model, we first find the draw reaction with the most flux
    +0097     drawRxns = startsWith(m.rxns, 'usage_prot_');
    +0098     idxToIgnore = cellfun(@(x) find(strcmpi(model.rxns, ['usage_prot_' x])), protToIgnore);
    +0099     iteration = 1;
    +0100     while true
    +0101         [res,hs] = solveLP(m,0,[],hs); %skip parsimonius, only takes time
    +0102         if isempty(res.f)
    +0103             printOrange('WARNING: The model has no feasible solution with the increased kcats, tuning stops.\n');
    +0104             break;
    +0105         end
    +0106         if ~isnan(lastGrowth) && res.f <= lastGrowth + growthStallTol
    +0107             printOrange('WARNING: No growth increase from increased kcats - check if the constraints on the uptake reactions are too tight.\n');
    +0108             break;
    +0109         end
    +0110         lastGrowth = res.f;
    +0111         if verbose; disp(['Iteration ' num2str(iteration) ': Growth: ' num2str(lastGrowth)]); end
    +0112         if (lastGrowth >= desiredGrowthRate)
    +0113             break;
    +0114         end
    +0115         %If you get an error here, it is likely due to numerical issues in the solver
    +0116         %The trick where we don't allow low kcats is to fix that, but maybe
    +0117         %it is not enough.
    +0118         iteration            = iteration + 1;
    +0119         %find the highest draw_prot rxn flux
    +0120         drawFluxes           = zeros(length(drawRxns),1);
    +0121         drawFluxes(drawRxns) = res.x(drawRxns);
    +0122         % Remove from the list user defined proteins
    +0123         drawFluxes(idxToIgnore) = 0;
    +0124         if ~any(drawFluxes > 0)
    +0125             printOrange('WARNING: No protein usage reaction carries flux, tuning cannot continue.\n');
    +0126             break;
    +0127         end
    +0128         [~,sel]              = max(drawFluxes); % since bounds 0 to 1000
    +0129         %Now get the metabolite
    +0130         metSel               = m.S(:,sel) > 0; % positive coeff (forward usage)
    +0131         %now find the reaction with the largest consumption of this protein
    +0132         protFluxes           = m.S(metSel,:).' .* res.x; %negative
    +0133         [~,rxnSel]           = min(protFluxes);
    +0134         kcatList             = [kcatList, rxnSel];
    +0135         rxn                  = m.rxns(rxnSel);
    +0136         targetSubRxn         = strcmp(m.ec.rxns, rxn);
    +0137         if ~strcmp(m.ec.source(targetSubRxn),'sensitivityTuning')
    +0138             oldNote          = m.ec.notes{targetSubRxn};
    +0139             newNote          = ['preTuneKcat=' num2str(m.ec.kcat(targetSubRxn)) ' | source:' m.ec.source{targetSubRxn}];
    +0140             if ~isempty(oldNote)
    +0141                 newNote      = [oldNote '; ' newNote];
    +0142             end
    +0143             m.ec.notes{targetSubRxn}    = newNote;
    +0144         end
    +0145         m.ec.kcat(targetSubRxn)     = m.ec.kcat(targetSubRxn) .* foldChange;
    +0146         m.ec.source(targetSubRxn)   = {'sensitivityTuning'};
    +0147         m                    = applyKcatConstraints(m,targetSubRxn);
    +0148     end
    +0149 
    +0150 else
    +0151     origRxns = extractAfter(m.ec.rxns,4);
    +0152     %find the reactions involved in proteins to be ignored
    +0153     idxToIgnore = cellfun(@(x) find(m.ec.rxnEnzMat(:, strcmpi(m.ec.enzymes, x))), protToIgnore, 'UniformOutput', false);
    +0154     %create an unique vector
    +0155     idxToIgnore = unique(cat(1, idxToIgnore{:}));
    +0156     %get the correct idx in model.rxns
    +0157     idxToIgnore = cellfun(@(x) find(strcmpi(m.rxns, x)), origRxns(idxToIgnore));
    +0158     iteration = 1;
    +0159     while true
    +0160         res = solveLP(m,0); %skip parsimonius, only takes time
    +0161         if isempty(res.f)
    +0162             printOrange('WARNING: The model has no feasible solution with the increased kcats, tuning stops.\n');
    +0163             break;
    +0164         end
    +0165         if ~isnan(lastGrowth) && res.f <= lastGrowth + growthStallTol
    +0166             printOrange('No growth increase from increased kcats - check if the constraints on the uptake reactions are too tight.\n');
    +0167             break;
    +0168         end
    +0169         lastGrowth = res.f;
    +0170         if (lastGrowth >= desiredGrowthRate)
    +0171             break;
    +0172         end
    +0173         %If you get an error here, it is likely due to numerical issues in the solver
    +0174         %The trick where we don't allow low kcats is to fix that, but maybe
    +0175         %it is not enough.
    +0176         if verbose; disp(['Iteration ' num2str(iteration) ': Growth: ' num2str(lastGrowth)]); end
    +0177         iteration       = iteration + 1;
    +0178         %find the highest protein usage flux
    +0179         protPoolStoich  = m.S(strcmp(m.mets, 'prot_pool'),:).';
    +0180         protPoolStoich(idxToIgnore) = 0;
    +0181         if ~any(res.x .* protPoolStoich < 0)
    +0182             printOrange('WARNING: No reaction draws on the protein pool, tuning cannot continue.\n');
    +0183             break;
    +0184         end
    +0185         [~,sel]         = min(res.x .* protPoolStoich); %max consumption
    +0186         kcatList        = [kcatList, sel];
    +0187         rxn             = m.rxns(sel.');
    +0188         targetSubRxns   = strcmp(origRxns, rxn);
    +0189         m.ec.kcat(targetSubRxns) = m.ec.kcat(targetSubRxns) .* foldChange;
    +0190         m               = applyKcatConstraints(m,rxn);
    +0191     end
    +0192 end
    +0193 
    +0194 kcatList        = unique(kcatList);
    +0195 tunedKcats.rxns = m.rxns(kcatList);
    +0196 tunedKcats.rxnNames = m.rxnNames(kcatList);
    +0197 if ~model.ec.geckoLight
    +0198     [~, rxnIdx]     = ismember(tunedKcats.rxns,m.ec.rxns);
    +0199 else
    +0200     [~, rxnIdx]     = ismember(tunedKcats.rxns,origRxns);
    +0201 end
    +0202 tunedKcats.enzymes  = cell(numel(kcatList),1);
    +0203 for i=1:numel(rxnIdx)
    +0204     [~, metIdx]     = find(m.ec.rxnEnzMat(rxnIdx(i),:));
    +0205     tunedKcats.enzymes{i}   = strjoin(m.ec.enzymes(metIdx),';');
    +0206 end
    +0207 tunedKcats.oldKcat  = model.ec.kcat(rxnIdx);
    +0208 tunedKcats.newKcat  = m.ec.kcat(rxnIdx);
    +0209 tunedKcats.source   = model.ec.source(rxnIdx);
    +0210 
    +0211 model = m;
    +0212 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/sigmaFitter.html b/doc/src/kcat_tuning/sigmaFitter.html new file mode 100644 index 00000000..01d755a6 --- /dev/null +++ b/doc/src/kcat_tuning/sigmaFitter.html @@ -0,0 +1,200 @@ + + + + Description of sigmaFitter + + + + + + + + + +
    Home > src > kcat_tuning > sigmaFitter.m
    + + + +

    sigmaFitter +

    + +

    PURPOSE ^

    +
    sigmaFitter Fit the average enzyme saturation factor of an ecModel.
    + +

    SYNOPSIS ^

    +
    function [model, sigma] = sigmaFitter(model, varargin)
    + +

    DESCRIPTION ^

    +
     sigmaFitter  Fit the average enzyme saturation factor of an ecModel.
    +
    + Scans candidate sigma-factors from 0.01 to 1 in steps of 0.01 and picks the
    + one whose simulated growth rate best matches the provided experimental
    + growth rate, then applies it to the model's protein pool constraint.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + growthRate : double
    +     growth rate that should be reached (default: read from the model
    +     adapter).
    + Ptot : double
    +     total cellular protein content in g/gDCW (default: read from the model
    +     adapter; if not specified there, 0.5 g/gDCW is assumed).
    + f : double
    +     estimated fraction of enzymes in the model (default: read from the
    +     model adapter; if not specified there, 0.5 is assumed).
    + makePlot : logical
    +     whether a plot should be made (default true).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + model : struct
    +     ecModel with protein pool exchange upper bound adapted to the optimal
    +     sigma-factor.
    + sigma : double
    +     optimal sigma-factor.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     [model, sigma] = sigmaFitter(model);
    +     [model, sigma] = sigmaFitter(model, 'makePlot', false);
    +     [model, sigma] = sigmaFitter(model, growthRate, Ptot, f, makePlot, modelAdapter);
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function [model, sigma] = sigmaFitter(model, varargin)
    +0002 % sigmaFitter  Fit the average enzyme saturation factor of an ecModel.
    +0003 %
    +0004 % Scans candidate sigma-factors from 0.01 to 1 in steps of 0.01 and picks the
    +0005 % one whose simulated growth rate best matches the provided experimental
    +0006 % growth rate, then applies it to the model's protein pool constraint.
    +0007 %
    +0008 % Parameters
    +0009 % ----------
    +0010 % model : struct
    +0011 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0012 %
    +0013 % Name-Value Arguments
    +0014 % --------------------
    +0015 % growthRate : double
    +0016 %     growth rate that should be reached (default: read from the model
    +0017 %     adapter).
    +0018 % Ptot : double
    +0019 %     total cellular protein content in g/gDCW (default: read from the model
    +0020 %     adapter; if not specified there, 0.5 g/gDCW is assumed).
    +0021 % f : double
    +0022 %     estimated fraction of enzymes in the model (default: read from the
    +0023 %     model adapter; if not specified there, 0.5 is assumed).
    +0024 % makePlot : logical
    +0025 %     whether a plot should be made (default true).
    +0026 % modelAdapter : ModelAdapter
    +0027 %     a loaded model adapter (default: the current default model adapter).
    +0028 %
    +0029 % Returns
    +0030 % -------
    +0031 % model : struct
    +0032 %     ecModel with protein pool exchange upper bound adapted to the optimal
    +0033 %     sigma-factor.
    +0034 % sigma : double
    +0035 %     optimal sigma-factor.
    +0036 %
    +0037 % Examples
    +0038 % --------
    +0039 %     % optional arguments may be given positionally or as name-value pairs:
    +0040 %     [model, sigma] = sigmaFitter(model);
    +0041 %     [model, sigma] = sigmaFitter(model, 'makePlot', false);
    +0042 %     [model, sigma] = sigmaFitter(model, growthRate, Ptot, f, makePlot, modelAdapter);
    +0043 
    +0044 p = parseGECKOargs(varargin, { ...
    +0045     'growthRate',   []; ...
    +0046     'Ptot',         []; ...
    +0047     'f',            []; ...
    +0048     'makePlot',     true; ...
    +0049     'modelAdapter', []});
    +0050 growthRate   = p.growthRate;
    +0051 Ptot         = p.Ptot;
    +0052 f            = p.f;
    +0053 makePlot     = p.makePlot;
    +0054 modelAdapter = p.modelAdapter;
    +0055 
    +0056 if isempty(modelAdapter)
    +0057     modelAdapter = ModelAdapterManager.getDefault();
    +0058     if isempty(modelAdapter)
    +0059         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0060     end
    +0061 end
    +0062 
    +0063 if isempty(makePlot)
    +0064     makePlot = true;
    +0065 end
    +0066 if isempty(f)
    +0067     f = modelAdapter.getParameters().f;
    +0068 end
    +0069 if isempty(Ptot)
    +0070     Ptot = modelAdapter.getParameters().Ptot;
    +0071 end
    +0072 if isempty(growthRate)
    +0073     growthRate = modelAdapter.getParameters().gR_exp;
    +0074 end
    +0075 
    +0076 objValues = [];
    +0077 errors    = [];
    +0078 sigParam  = [];
    +0079 objPos    = find(model.c);
    +0080 %Relax bounds for the objective function
    +0081 model.lb(objPos) = 0;
    +0082 model.ub(objPos) = 1000;
    +0083 hsSol=[];
    +0084 for i=1:100
    +0085     %Constrains the ecModel with the i-th sigma factor
    +0086     sigma = i/100;
    +0087     model = setProtPoolSize(model, Ptot, f, sigma, modelAdapter);
    +0088     [solution, hsSol]  = solveLP(model,0,[],hsSol);
    +0089     if isempty(solution.x)
    +0090         solution.x=zeros(length(model.rxns),1);
    +0091     end
    +0092     objValues = [objValues; solution.x(objPos)];
    +0093     error     = abs(((growthRate-solution.x(objPos))/growthRate)*100);
    +0094     errors    = [errors; error];
    +0095     error     = num2str(((growthRate-solution.x(objPos))/growthRate)*100);
    +0096     sigParam  = [sigParam; sigma];
    +0097 end
    +0098 [~, minIndx] = min(errors);
    +0099 sigma     = sigParam(minIndx);
    +0100 % The loop above leaves the protein pool sized for the *last* sigma tried
    +0101 % (i=100, i.e. sigma=1), not the best-fitting one found by the search --
    +0102 % re-apply it here so the returned model actually matches the returned
    +0103 % sigma, per this function's own documented contract ("ecModel with
    +0104 % protein pool exchange upper bound adapted to the optimal sigma-factor").
    +0105 model = setProtPoolSize(model, Ptot, f, sigma, modelAdapter);
    +0106 if makePlot
    +0107     figure
    +0108     plot(sigParam,errors,'LineWidth',5)
    +0109     title('Sigma fitting')
    +0110     xlabel('Average enzyme saturation [-]')
    +0111     ylabel('Absolute relative error [%]')
    +0112 end
    +0113 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/kcat_tuning/truncateValues.html b/doc/src/kcat_tuning/truncateValues.html new file mode 100644 index 00000000..d7ad3712 --- /dev/null +++ b/doc/src/kcat_tuning/truncateValues.html @@ -0,0 +1,92 @@ + + + + Description of truncateValues + + + + + + + + + +
    Home > src > kcat_tuning > truncateValues.m
    + + + +

    truncateValues +

    + +

    PURPOSE ^

    +
    truncateValues Round values in selected columns to six significant digits.
    + +

    SYNOPSIS ^

    +
    function table = truncateValues(table,cols)
    + +

    DESCRIPTION ^

    +
     truncateValues  Round values in selected columns to six significant digits.
    +
    + Rounds each value in the given columns of a cell array or table to six
    + significant digits, based on the value's order of magnitude.
    +
    + Parameters
    + ----------
    + table : cell or table
    +     a cell array or table where some columns have values that should be
    +     truncated.
    + cols : double
    +     index or indices of columns with values to be truncated.
    +
    + Returns
    + -------
    + table : cell or table
    +     the input with the selected columns rounded.
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function table = truncateValues(table,cols)
    +0002 % truncateValues  Round values in selected columns to six significant digits.
    +0003 %
    +0004 % Rounds each value in the given columns of a cell array or table to six
    +0005 % significant digits, based on the value's order of magnitude.
    +0006 %
    +0007 % Parameters
    +0008 % ----------
    +0009 % table : cell or table
    +0010 %     a cell array or table where some columns have values that should be
    +0011 %     truncated.
    +0012 % cols : double
    +0013 %     index or indices of columns with values to be truncated.
    +0014 %
    +0015 % Returns
    +0016 % -------
    +0017 % table : cell or table
    +0018 %     the input with the selected columns rounded.
    +0019 
    +0020 [m,n] = size(table);
    +0021 for i = 1:m
    +0022     for j = cols
    +0023         orderMagn  = max([ceil(log10(abs(table{i,j}))),0]);
    +0024         table{i,j} = round(table{i,j},6-orderMagn);
    +0025     end
    +0026 end
    +0027 end
    +0028 
    +0029 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/limit_proteins/calculateFfactor.html b/doc/src/limit_proteins/calculateFfactor.html new file mode 100644 index 00000000..b8185395 --- /dev/null +++ b/doc/src/limit_proteins/calculateFfactor.html @@ -0,0 +1,190 @@ + + + + Description of calculateFfactor + + + + + + + + + +
    Home > src > limit_proteins > calculateFfactor.m
    + + + +

    calculateFfactor +

    + +

    PURPOSE ^

    +
    calculateFfactor Compute the f factor for an ecModel.
    + +

    SYNOPSIS ^

    +
    function f = calculateFfactor(model, varargin)
    + +

    DESCRIPTION ^

    +
     calculateFfactor  Compute the f factor for an ecModel.
    +
    + Computes the f factor, as a proxy to the mass fraction of proteins
    + accounted for in an ecModel out of the total protein content in cells.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + protData : struct
    +     structure with proteome data, from loadProtData (by default it instead
    +     attempts to load data/paxDB.tsv).
    + enzymes : cell
    +     list of enzymes (default model.ec.enzymes).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + f : double
    +     f-factor.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     f = calculateFfactor(model);
    +     f = calculateFfactor(model, 'enzymes', enzymes);
    +
    + See also
    + --------
    + loadProtData, getProtFromProteomics
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function f = calculateFfactor(model, varargin)
    +0002 % calculateFfactor  Compute the f factor for an ecModel.
    +0003 %
    +0004 % Computes the f factor, as a proxy to the mass fraction of proteins
    +0005 % accounted for in an ecModel out of the total protein content in cells.
    +0006 %
    +0007 % Parameters
    +0008 % ----------
    +0009 % model : struct
    +0010 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0011 %
    +0012 % Name-Value Arguments
    +0013 % --------------------
    +0014 % protData : struct
    +0015 %     structure with proteome data, from loadProtData (by default it instead
    +0016 %     attempts to load data/paxDB.tsv).
    +0017 % enzymes : cell
    +0018 %     list of enzymes (default model.ec.enzymes).
    +0019 % modelAdapter : ModelAdapter
    +0020 %     a loaded model adapter (default: the current default model adapter).
    +0021 %
    +0022 % Returns
    +0023 % -------
    +0024 % f : double
    +0025 %     f-factor.
    +0026 %
    +0027 % Examples
    +0028 % --------
    +0029 %     % optional arguments may be given positionally or as name-value pairs:
    +0030 %     f = calculateFfactor(model);
    +0031 %     f = calculateFfactor(model, 'enzymes', enzymes);
    +0032 %
    +0033 % See also
    +0034 % --------
    +0035 % loadProtData, getProtFromProteomics
    +0036 
    +0037 p = parseGECKOargs(varargin, { ...
    +0038     'protData',     []; ...
    +0039     'enzymes',      []; ...
    +0040     'modelAdapter', []});
    +0041 protData     = p.protData;
    +0042 enzymes      = p.enzymes;
    +0043 modelAdapter = p.modelAdapter;
    +0044 
    +0045 if isempty(modelAdapter)
    +0046     modelAdapter = ModelAdapterManager.getDefault();
    +0047     if isempty(modelAdapter)
    +0048         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0049     end
    +0050 end
    +0051 params = modelAdapter.getParameters();
    +0052 
    +0053 if isempty(enzymes)
    +0054     enzymes = model.ec.enzymes;
    +0055 end
    +0056 
    +0057 % Gather proteome data in protData structure
    +0058 if isempty(protData)
    +0059     if exist(fullfile(params.path,'data','paxDB.tsv'),'file')
    +0060         protData = fullfile(params.path,'data','paxDB.tsv');
    +0061     else
    +0062         printOrange('WARNING: No proteomics data is provided or can be found. Default f value of 0.5 is returned.\n');
    +0063         f = 0.5;
    +0064         return
    +0065     end
    +0066 end
    +0067 
    +0068 if ischar(protData) && endsWith(protData,'paxDB.tsv')
    +0069     % Gather Uniprot database for finding MW. Only needed here, to map paxDB.tsv's gene
    +0070     % identifiers onto UniProt IDs and molecular weights --- a protData struct supplied by
    +0071     % the caller already carries UniProt IDs and needs no lookup, so this stays inside the
    +0072     % branch that actually uses it rather than running (and potentially downloading or
    +0073     % reading UniProt data) on every call.
    +0074     uniprotDB = loadDatabases('uniprot', modelAdapter);
    +0075     uniprotDB = uniprotDB.uniprot;
    +0076 
    +0077     fID         = fopen(fullfile(protData),'r');
    +0078     fileContent = textscan(fID,'%s','delimiter','\n');
    +0079     headerLines = find(startsWith(fileContent{1},'#'),1,'last');
    +0080     fclose(fID);
    +0081 
    +0082     %Read data file, excluding headerlines
    +0083     fID         = fopen(fullfile(protData),'r');
    +0084     fileContent = textscan(fID,'%s %s %f','delimiter','\t','HeaderLines',headerLines);
    +0085     genes       = fileContent{2};
    +0086     %Remove internal geneIDs modifiers
    +0087     genes       = regexprep(genes,'^\d+\.','');
    +0088     level       = fileContent{3};
    +0089     fclose(fID);
    +0090     [a,b]       = ismember(genes,uniprotDB.genes);
    +0091     uniprot     = uniprotDB.ID(b(a));
    +0092     level(~a)   = [];
    +0093     clear protData
    +0094     protData.uniprotIDs = uniprot;
    +0095     protData.level   = level;
    +0096     % Get MW and abundance (unit does not matter, f is fraction)
    +0097     [~,idx] = ismember(protData.uniprotIDs,uniprotDB.ID);
    +0098     protData.MW = uniprotDB.MW(idx);
    +0099     protData.abundances = protData.level .* protData.MW;
    +0100 end
    +0101 
    +0102 avgAbundances = mean(protData.abundances,2);
    +0103 totalProt = sum(avgAbundances,'omitnan');
    +0104 
    +0105 % Get enzymes in model
    +0106 enzymesInModel = ismember(protData.uniprotIDs,enzymes);
    +0107 totalEnz = sum(avgAbundances(enzymesInModel),'omitnan');
    +0108 
    +0109 f = totalEnz/totalProt;
    +0110 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/limit_proteins/constrainEnzConcs.html b/doc/src/limit_proteins/constrainEnzConcs.html new file mode 100644 index 00000000..9842b8ab --- /dev/null +++ b/doc/src/limit_proteins/constrainEnzConcs.html @@ -0,0 +1,161 @@ + + + + Description of constrainEnzConcs + + + + + + + + + +
    Home > src > limit_proteins > constrainEnzConcs.m
    + + + +

    constrainEnzConcs +

    + +

    PURPOSE ^

    +
    constrainEnzConcs Constrain enzyme usages by their concentration.
    + +

    SYNOPSIS ^

    +
    function model = constrainEnzConcs(model, varargin)
    + +

    DESCRIPTION ^

    +
     constrainEnzConcs  Constrain enzyme usages by their concentration.
    +
    + Constrain enzyme usages by their concentration as provided in
    + model.ec.concs. For enzymes with non-NaN entries in model.ec.concs, their
    + enzyme usage reaction will no longer draw from the protein pool, but is
    + rather constraint by the measured protein abundance.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure) with enzyme
    +     concentrations in model.ec.concs.
    +
    + Name-Value Arguments
    + --------------------
    + removeConstraints : logical
    +     whether enzyme concentration constraints should be removed
    +     (model.ec.concs will remain unchanged) (default false).
    +
    + Returns
    + -------
    + model : struct
    +     an ecModel constraint with available enzyme concentrations.
    +
    + Notes
    + -----
    + To populate model.ec.concs you should run fillEnzConcs.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     model = constrainEnzConcs(model);
    +     model = constrainEnzConcs(model, 'removeConstraints', true);
    +
    + See also
    + --------
    + fillEnzConcs
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function model = constrainEnzConcs(model, varargin)
    +0002 % constrainEnzConcs  Constrain enzyme usages by their concentration.
    +0003 %
    +0004 % Constrain enzyme usages by their concentration as provided in
    +0005 % model.ec.concs. For enzymes with non-NaN entries in model.ec.concs, their
    +0006 % enzyme usage reaction will no longer draw from the protein pool, but is
    +0007 % rather constraint by the measured protein abundance.
    +0008 %
    +0009 % Parameters
    +0010 % ----------
    +0011 % model : struct
    +0012 %     an ecModel in GECKO 3 format (with ecModel.ec structure) with enzyme
    +0013 %     concentrations in model.ec.concs.
    +0014 %
    +0015 % Name-Value Arguments
    +0016 % --------------------
    +0017 % removeConstraints : logical
    +0018 %     whether enzyme concentration constraints should be removed
    +0019 %     (model.ec.concs will remain unchanged) (default false).
    +0020 %
    +0021 % Returns
    +0022 % -------
    +0023 % model : struct
    +0024 %     an ecModel constraint with available enzyme concentrations.
    +0025 %
    +0026 % Notes
    +0027 % -----
    +0028 % To populate model.ec.concs you should run fillEnzConcs.
    +0029 %
    +0030 % Examples
    +0031 % --------
    +0032 %     % optional arguments may be given positionally or as name-value pairs:
    +0033 %     model = constrainEnzConcs(model);
    +0034 %     model = constrainEnzConcs(model, 'removeConstraints', true);
    +0035 %
    +0036 % See also
    +0037 % --------
    +0038 % fillEnzConcs
    +0039 
    +0040 %Enzyme with NaN entry in model.ec.concs => draw from prot_pool
    +0041 %Enzyme with numeric entry in model.ec.concs => exchange reaction with
    +0042 %enzyme level as UB
    +0043 
    +0044 p = parseGECKOargs(varargin, { ...
    +0045     'removeConstraints', false});
    +0046 removeConstraints = p.removeConstraints;
    +0047 
    +0048 %Get indices of usage reactions
    +0049 usageRxns = strcat('usage_prot_',model.ec.enzymes);
    +0050 [~, usageRxnsIdx] = ismember(usageRxns, model.rxns);
    +0051 
    +0052 if any(usageRxnsIdx == 0)
    +0053     error('Usage reactions are not defined for all enzymes. This is done by makeEcModel.')
    +0054 end
    +0055 %Get index of protein pool metabolite
    +0056 protPoolIdx = find(ismember(model.mets,'prot_pool'));
    +0057 if ~any(protPoolIdx)
    +0058     error('Cannot find protein pool pseudometabolite.')
    +0059 end
    +0060 
    +0061 %Protein that should be constraint by UB
    +0062 if removeConstraints
    +0063     protCons = [];
    +0064 else
    +0065     protCons = ~isnan(model.ec.concs);
    +0066 end
    +0067 
    +0068 %Set all reactions to draw from prot_pool (forward: prot_pool -> prot_<id>)
    +0069 model.S(protPoolIdx, usageRxnsIdx) = -1;
    +0070 model.lb(usageRxnsIdx) = 0;
    +0071 model.ub(usageRxnsIdx) = 1000;
    +0072 
    +0073 %If non-NaN in model.ec.concs, then constrain by UB
    +0074 if any(protCons)
    +0075 %    model.S(protPoolIdx, usageRxnsIdx(protCons)) = 0; % Since GECKO 3.2.0
    +0076     model.ub(usageRxnsIdx(protCons)) = model.ec.concs(protCons);
    +0077 end
    +0078 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/limit_proteins/constrainFluxData.html b/doc/src/limit_proteins/constrainFluxData.html new file mode 100644 index 00000000..4967c2b1 --- /dev/null +++ b/doc/src/limit_proteins/constrainFluxData.html @@ -0,0 +1,264 @@ + + + + Description of constrainFluxData + + + + + + + + + +
    Home > src > limit_proteins > constrainFluxData.m
    + + + +

    constrainFluxData +

    + +

    PURPOSE ^

    +
    constrainFluxData Constrain ecModel fluxes to provided flux data.
    + +

    SYNOPSIS ^

    +
    function model = constrainFluxData(model, varargin)
    + +

    DESCRIPTION ^

    +
     constrainFluxData  Constrain ecModel fluxes to provided flux data.
    +
    + Constrains fluxes to the data that is provided in the fluxData structure,
    + which itself is read by loadFluxData from data/fluxData.tsv.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + fluxData : struct
    +     structure with flux data, with the fields:
    +
    +     - conds : sampling condition.
    +     - Ptot : total protein (g/gDCW).
    +     - grRate : growth rate (1/h).
    +     - exchFluxes : exchange fluxes (mmol/gDCWh).
    +     - exchMets : exchanged metabolites, matching exchFluxes.
    +     - exchRxnIDs : exchange reaction IDs, matching exchMets.
    + condition : double or char
    +     either index number or name of the sample condition in fluxData.conds
    +     (default 1).
    + maxMinGrowth : char
    +     'max' if the provided growth rate should be set as maximum growth rate
    +     (= upper bound), or 'min' if it should be set as minimum growth rate
    +     (= lower bound). The latter option is suitable if minimization of
    +     prot_pool_exchange is used as objective function (default 'max').
    + looseStrictFlux : char or double
    +     how strictly constrained the exchange fluxes should be (default
    +     'loose'):
    +
    +     - 'loose' : the exchange fluxes are constraint only by the "outer
    +       bounds". If exchFluxes(i) > 0, LB = 0 and UB = exchFluxes(i). If
    +       exchFluxes(i) < 0, LB = exchFluxes(i) and UB = 0.
    +     - 0-100 : LB and UB constraints are set with a specified percentage of
    +       variance around exchFluxes. If 10 is specified, LB = exchFluxes*0.95
    +       and UB = exchFluxes*1.05. This allows for 10% variance around the
    +       exchFluxes values, but strictly forces a flux through the exchRxns.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + model : struct
    +     an ecModel where fluxes are constraint.
    +
    + Notes
    + -----
    + If a provided constraint is either -1000 or 1000, then the function will
    + update the reaction lower and upper bound to either allow uptake or
    + excretion, irrespective of what option is given as the looseStrictFlux
    + parameter.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     model = constrainFluxData(model);
    +     model = constrainFluxData(model, 'condition', 2);
    +
    + See also
    + --------
    + loadFluxData
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function model = constrainFluxData(model, varargin)
    +0002 % constrainFluxData  Constrain ecModel fluxes to provided flux data.
    +0003 %
    +0004 % Constrains fluxes to the data that is provided in the fluxData structure,
    +0005 % which itself is read by loadFluxData from data/fluxData.tsv.
    +0006 %
    +0007 % Parameters
    +0008 % ----------
    +0009 % model : struct
    +0010 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0011 %
    +0012 % Name-Value Arguments
    +0013 % --------------------
    +0014 % fluxData : struct
    +0015 %     structure with flux data, with the fields:
    +0016 %
    +0017 %     - conds : sampling condition.
    +0018 %     - Ptot : total protein (g/gDCW).
    +0019 %     - grRate : growth rate (1/h).
    +0020 %     - exchFluxes : exchange fluxes (mmol/gDCWh).
    +0021 %     - exchMets : exchanged metabolites, matching exchFluxes.
    +0022 %     - exchRxnIDs : exchange reaction IDs, matching exchMets.
    +0023 % condition : double or char
    +0024 %     either index number or name of the sample condition in fluxData.conds
    +0025 %     (default 1).
    +0026 % maxMinGrowth : char
    +0027 %     'max' if the provided growth rate should be set as maximum growth rate
    +0028 %     (= upper bound), or 'min' if it should be set as minimum growth rate
    +0029 %     (= lower bound). The latter option is suitable if minimization of
    +0030 %     prot_pool_exchange is used as objective function (default 'max').
    +0031 % looseStrictFlux : char or double
    +0032 %     how strictly constrained the exchange fluxes should be (default
    +0033 %     'loose'):
    +0034 %
    +0035 %     - 'loose' : the exchange fluxes are constraint only by the "outer
    +0036 %       bounds". If exchFluxes(i) > 0, LB = 0 and UB = exchFluxes(i). If
    +0037 %       exchFluxes(i) < 0, LB = exchFluxes(i) and UB = 0.
    +0038 %     - 0-100 : LB and UB constraints are set with a specified percentage of
    +0039 %       variance around exchFluxes. If 10 is specified, LB = exchFluxes*0.95
    +0040 %       and UB = exchFluxes*1.05. This allows for 10% variance around the
    +0041 %       exchFluxes values, but strictly forces a flux through the exchRxns.
    +0042 % modelAdapter : ModelAdapter
    +0043 %     a loaded model adapter (default: the current default model adapter).
    +0044 %
    +0045 % Returns
    +0046 % -------
    +0047 % model : struct
    +0048 %     an ecModel where fluxes are constraint.
    +0049 %
    +0050 % Notes
    +0051 % -----
    +0052 % If a provided constraint is either -1000 or 1000, then the function will
    +0053 % update the reaction lower and upper bound to either allow uptake or
    +0054 % excretion, irrespective of what option is given as the looseStrictFlux
    +0055 % parameter.
    +0056 %
    +0057 % Examples
    +0058 % --------
    +0059 %     % optional arguments may be given positionally or as name-value pairs:
    +0060 %     model = constrainFluxData(model);
    +0061 %     model = constrainFluxData(model, 'condition', 2);
    +0062 %
    +0063 % See also
    +0064 % --------
    +0065 % loadFluxData
    +0066 
    +0067 p = parseGECKOargs(varargin, { ...
    +0068     'fluxData',        []; ...
    +0069     'condition',       []; ...
    +0070     'maxMinGrowth',    []; ...
    +0071     'looseStrictFlux', []; ...
    +0072     'modelAdapter',    []});
    +0073 fluxData        = p.fluxData;
    +0074 condition       = p.condition;
    +0075 maxMinGrowth    = p.maxMinGrowth;
    +0076 looseStrictFlux = p.looseStrictFlux;
    +0077 modelAdapter    = p.modelAdapter;
    +0078 
    +0079 if isempty(modelAdapter)
    +0080     modelAdapter = ModelAdapterManager.getDefault();
    +0081     if isempty(modelAdapter)
    +0082         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0083     end
    +0084 end
    +0085 params = modelAdapter.getParameters();
    +0086 
    +0087 if isempty(looseStrictFlux)
    +0088     looseStrictFlux = 'loose';
    +0089 end
    +0090 
    +0091 if isempty(maxMinGrowth)
    +0092     maxMinGrowth = 'max';
    +0093 end
    +0094 
    +0095 if isempty(fluxData)
    +0096     fluxData = loadFluxData(fullfile(params.path,'data','fluxData.tsv'),modelAdapter);
    +0097 end
    +0098 
    +0099 if isempty(condition)
    +0100     condition = 1;
    +0101 elseif ~isnumeric(condition)
    +0102     idx = find(strcmp(fluxData.conds,condition));
    +0103     if isempty(condition)
    +0104         error(['Condition ' condition ' cannot be found in fluxData'])
    +0105     else
    +0106         condition = idx;
    +0107     end
    +0108 end
    +0109 
    +0110 % Select the exchange fluxes of specified condition
    +0111 fluxData.exchFluxes = fluxData.exchFluxes(condition,:);
    +0112 
    +0113 %Set original c-source to zero
    +0114 model = setParam(model,'eq',params.c_source,0);
    +0115 %Set growth
    +0116 switch maxMinGrowth
    +0117     case 'max'
    +0118         model = setParam(model,'lb',params.bioRxn,0);
    +0119         model = setParam(model,'ub',params.bioRxn,fluxData.grRate(condition));
    +0120     case 'min'
    +0121         model = setParam(model,'lb',params.bioRxn,fluxData.grRate(condition));
    +0122         model = setParam(model,'ub',params.bioRxn,1000);
    +0123 end
    +0124 
    +0125 naFlux = isnan(fluxData.exchFluxes);
    +0126 negFlux = lt(fluxData.exchFluxes,0); % less than 0
    +0127 ub = fluxData.exchFluxes(~(negFlux | naFlux));
    +0128 posFlux = fluxData.exchRxnIDs(~(negFlux | naFlux));
    +0129 lb = fluxData.exchFluxes(negFlux & ~naFlux);
    +0130 negFlux = fluxData.exchRxnIDs(negFlux & ~naFlux);
    +0131 
    +0132 switch looseStrictFlux
    +0133     case 'loose'
    +0134         model = setParam(model,'lb',negFlux,lb);
    +0135         model = setParam(model,'ub',negFlux,0);
    +0136         model = setParam(model,'lb',posFlux,0);
    +0137         model = setParam(model,'ub',posFlux,ub);
    +0138     otherwise
    +0139         model = setParam(model,'var',negFlux,lb,looseStrictFlux);
    +0140         model = setParam(model,'var',posFlux,ub,looseStrictFlux);
    +0141 end
    +0142 extremeFlux = find(abs(fluxData.exchFluxes)==1000);
    +0143 if any(extremeFlux)
    +0144     exchFlux = fluxData.exchFluxes(extremeFlux);
    +0145     if any(exchFlux==-1000)
    +0146         model = setParam(model,'lb',fluxData.exchRxnIDs(extremeFlux(exchFlux==-1000)),-1000);
    +0147         model = setParam(model,'ub',fluxData.exchRxnIDs(extremeFlux(exchFlux==-1000)),0);
    +0148     end
    +0149     if any(exchFlux==1000)
    +0150         model = setParam(model,'lb',fluxData.exchRxnIDs(extremeFlux(exchFlux==1000)),0);
    +0151         model = setParam(model,'ub',fluxData.exchRxnIDs(extremeFlux(exchFlux==1000)),1000);
    +0152     end
    +0153 end
    +0154 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/limit_proteins/fillEnzConcs.html b/doc/src/limit_proteins/fillEnzConcs.html new file mode 100644 index 00000000..03abdcda --- /dev/null +++ b/doc/src/limit_proteins/fillEnzConcs.html @@ -0,0 +1,152 @@ + + + + Description of fillEnzConcs + + + + + + + + + +
    Home > src > limit_proteins > fillEnzConcs.m
    + + + +

    fillEnzConcs +

    + +

    PURPOSE ^

    +
    fillEnzConcs Populate model.ec.concs from proteome data.
    + +

    SYNOPSIS ^

    +
    function model = fillEnzConcs(model, protData, varargin)
    + +

    DESCRIPTION ^

    +
     fillEnzConcs  Populate model.ec.concs from proteome data.
    +
    + Uses the protein concentrations from protData to fill model.ec.concs.
    + Protein levels should be provided in mg/gDCW. If no data is provided for a
    + particular protein, its level is NaN. Existing entries in model.ec.concs
    + are overwritten.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    + protData : struct
    +     structure with proteome data, from loadProtFluxData, with the fields:
    +
    +     - uniprotIDs : cell array with Uniprot IDs matching protData.abundances.
    +     - abundances : matrix of proteomics data.
    +
    + Name-Value Arguments
    + --------------------
    + dataCol : double
    +     number indicating the column in protData.abundances that contains the
    +     relevant protein concentrations. protData may contain data from
    +     multiple conditions/samples/experiments, each with their own column in
    +     protData.abundances (default 1).
    +
    + Returns
    + -------
    + model : struct
    +     an ecModel where model.ec.concs is populated with protein
    +     concentrations.
    +
    + Notes
    + -----
    + To also constrain the model with the content of model.ec.concs, you should
    + run constrainEnzConcs.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     model = fillEnzConcs(model, protData);
    +     model = fillEnzConcs(model, protData, 'dataCol', 2);
    +
    + See also
    + --------
    + constrainEnzConcs, loadProtFluxData
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function model = fillEnzConcs(model, protData, varargin)
    +0002 % fillEnzConcs  Populate model.ec.concs from proteome data.
    +0003 %
    +0004 % Uses the protein concentrations from protData to fill model.ec.concs.
    +0005 % Protein levels should be provided in mg/gDCW. If no data is provided for a
    +0006 % particular protein, its level is NaN. Existing entries in model.ec.concs
    +0007 % are overwritten.
    +0008 %
    +0009 % Parameters
    +0010 % ----------
    +0011 % model : struct
    +0012 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0013 % protData : struct
    +0014 %     structure with proteome data, from loadProtFluxData, with the fields:
    +0015 %
    +0016 %     - uniprotIDs : cell array with Uniprot IDs matching protData.abundances.
    +0017 %     - abundances : matrix of proteomics data.
    +0018 %
    +0019 % Name-Value Arguments
    +0020 % --------------------
    +0021 % dataCol : double
    +0022 %     number indicating the column in protData.abundances that contains the
    +0023 %     relevant protein concentrations. protData may contain data from
    +0024 %     multiple conditions/samples/experiments, each with their own column in
    +0025 %     protData.abundances (default 1).
    +0026 %
    +0027 % Returns
    +0028 % -------
    +0029 % model : struct
    +0030 %     an ecModel where model.ec.concs is populated with protein
    +0031 %     concentrations.
    +0032 %
    +0033 % Notes
    +0034 % -----
    +0035 % To also constrain the model with the content of model.ec.concs, you should
    +0036 % run constrainEnzConcs.
    +0037 %
    +0038 % Examples
    +0039 % --------
    +0040 %     % optional arguments may be given positionally or as name-value pairs:
    +0041 %     model = fillEnzConcs(model, protData);
    +0042 %     model = fillEnzConcs(model, protData, 'dataCol', 2);
    +0043 %
    +0044 % See also
    +0045 % --------
    +0046 % constrainEnzConcs, loadProtFluxData
    +0047 
    +0048 p = parseGECKOargs(varargin, { ...
    +0049     'dataCol', 1});
    +0050 dataCol = p.dataCol;
    +0051 if isempty(dataCol); dataCol = 1; end
    +0052 
    +0053 uniprotIDs = protData.uniprotIDs;
    +0054 abundances = protData.abundances(:,dataCol);
    +0055 
    +0056 %Redefine an empty model.ec.concs vector
    +0057 model.ec.concs=nan(numel(model.ec.enzymes),1);
    +0058 
    +0059 [a,b] = ismember(uniprotIDs, model.ec.enzymes);
    +0060 model.ec.concs(b(a)) = abundances(a);
    +0061 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/limit_proteins/flexibilizeEnzConcs.html b/doc/src/limit_proteins/flexibilizeEnzConcs.html new file mode 100644 index 00000000..41a2567e --- /dev/null +++ b/doc/src/limit_proteins/flexibilizeEnzConcs.html @@ -0,0 +1,381 @@ + + + + Description of flexibilizeEnzConcs + + + + + + + + + +
    Home > src > limit_proteins > flexibilizeEnzConcs.m
    + + + +

    flexibilizeEnzConcs +

    + +

    PURPOSE ^

    +
    flexibilizeEnzConcs Flexibilize enzyme concentrations of an ecModel.
    + +

    SYNOPSIS ^

    +
    function [model, flexEnz] = flexibilizeEnzConcs(model, varargin)
    + +

    DESCRIPTION ^

    +
     flexibilizeEnzConcs  Flexibilize enzyme concentrations of an ecModel.
    +
    + Flexibilize enzyme concentration of an ecModel constrained with proteomics
    + data. The upper bound of the protein usage reaction is changed, while the
    + concentrations in ecModel.ec.concs remain unchanged.
    +
    + If no (more) limiting enzyme concentrations can be found, it might be the
    + protein pool exchange that is limiting growth. In that case, an attempt
    + will be made to relax the protein pool exchange reaction, and if the growth
    + rate indeed increases, it is suggested to set the protein pool exchange
    + unconstrained (ub=1000) before again running flexibilizeEnzConcs. Such
    + situations, where a proteomics integrated ecModel is overconstrained, may
    + occur if the ecModel should be able to simulate maximum growth rate (from
    + e.g. batch cultivation).
    +
    + If relaxing the protein pool exchange does not increase the growth rate,
    + then this is not due to enzyme constraints, but rather an issue with the
    + metabolic network itself, or the set nutrient exchange is not sufficient.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + expGrowth : double
    +     estimated experimental growth rate. If not specified, the value will be
    +     read from the model adapter.
    + foldChange : double
    +     a value how much to increase the enzyme concentration (default 2).
    + iterPerEnzyme : double
    +     the number of iterations that an enzyme can be increased. A zero number
    +     can be defined; if zero is defined no limit will be set, and it will
    +     increase the enzyme concentration until it reaches the defined growth
    +     rate (default 5).
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    + verbose : logical
    +     whether progress should be reported (default true).
    +
    + Returns
    + -------
    + model : struct
    +     ecModel where the constraint of measured enzyme concentrations have
    +     been flexibilized (=relaxed) in the S-matrix, to allow the model to
    +     reach the growth rate defined in expGrowth, while the values in
    +     ecModel.ec.concs have remained untouched.
    + flexEnz : struct
    +     array with information about flexibilized proteins, with the fields:
    +
    +     - uniprotIDs : enzymes whose usage UB was flexibilized.
    +     - oldConcs : original concentrations, from model.ec.concs.
    +     - flexConcs : flexibilized concentrations, new UB in model.
    +     - ratioIncr : ratio by which the concentration increased; the enzymes
    +       will be sorted by this field.
    +     - frequence : numeric how often the enzyme has been step-wise
    +       flexibilized.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     [model, flexEnz] = flexibilizeEnzConcs(model);
    +     [model, flexEnz] = flexibilizeEnzConcs(model, 'foldChange', 3);
    +
    + See also
    + --------
    + constrainEnzConcs, getConcControlCoeffs
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: + +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function [model, flexEnz] = flexibilizeEnzConcs(model, varargin)
    +0002 % flexibilizeEnzConcs  Flexibilize enzyme concentrations of an ecModel.
    +0003 %
    +0004 % Flexibilize enzyme concentration of an ecModel constrained with proteomics
    +0005 % data. The upper bound of the protein usage reaction is changed, while the
    +0006 % concentrations in ecModel.ec.concs remain unchanged.
    +0007 %
    +0008 % If no (more) limiting enzyme concentrations can be found, it might be the
    +0009 % protein pool exchange that is limiting growth. In that case, an attempt
    +0010 % will be made to relax the protein pool exchange reaction, and if the growth
    +0011 % rate indeed increases, it is suggested to set the protein pool exchange
    +0012 % unconstrained (ub=1000) before again running flexibilizeEnzConcs. Such
    +0013 % situations, where a proteomics integrated ecModel is overconstrained, may
    +0014 % occur if the ecModel should be able to simulate maximum growth rate (from
    +0015 % e.g. batch cultivation).
    +0016 %
    +0017 % If relaxing the protein pool exchange does not increase the growth rate,
    +0018 % then this is not due to enzyme constraints, but rather an issue with the
    +0019 % metabolic network itself, or the set nutrient exchange is not sufficient.
    +0020 %
    +0021 % Parameters
    +0022 % ----------
    +0023 % model : struct
    +0024 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0025 %
    +0026 % Name-Value Arguments
    +0027 % --------------------
    +0028 % expGrowth : double
    +0029 %     estimated experimental growth rate. If not specified, the value will be
    +0030 %     read from the model adapter.
    +0031 % foldChange : double
    +0032 %     a value how much to increase the enzyme concentration (default 2).
    +0033 % iterPerEnzyme : double
    +0034 %     the number of iterations that an enzyme can be increased. A zero number
    +0035 %     can be defined; if zero is defined no limit will be set, and it will
    +0036 %     increase the enzyme concentration until it reaches the defined growth
    +0037 %     rate (default 5).
    +0038 % modelAdapter : ModelAdapter
    +0039 %     a loaded model adapter (default: the current default model adapter).
    +0040 % verbose : logical
    +0041 %     whether progress should be reported (default true).
    +0042 %
    +0043 % Returns
    +0044 % -------
    +0045 % model : struct
    +0046 %     ecModel where the constraint of measured enzyme concentrations have
    +0047 %     been flexibilized (=relaxed) in the S-matrix, to allow the model to
    +0048 %     reach the growth rate defined in expGrowth, while the values in
    +0049 %     ecModel.ec.concs have remained untouched.
    +0050 % flexEnz : struct
    +0051 %     array with information about flexibilized proteins, with the fields:
    +0052 %
    +0053 %     - uniprotIDs : enzymes whose usage UB was flexibilized.
    +0054 %     - oldConcs : original concentrations, from model.ec.concs.
    +0055 %     - flexConcs : flexibilized concentrations, new UB in model.
    +0056 %     - ratioIncr : ratio by which the concentration increased; the enzymes
    +0057 %       will be sorted by this field.
    +0058 %     - frequence : numeric how often the enzyme has been step-wise
    +0059 %       flexibilized.
    +0060 %
    +0061 % Examples
    +0062 % --------
    +0063 %     % optional arguments may be given positionally or as name-value pairs:
    +0064 %     [model, flexEnz] = flexibilizeEnzConcs(model);
    +0065 %     [model, flexEnz] = flexibilizeEnzConcs(model, 'foldChange', 3);
    +0066 %
    +0067 % See also
    +0068 % --------
    +0069 % constrainEnzConcs, getConcControlCoeffs
    +0070 
    +0071 p = parseGECKOargs(varargin, { ...
    +0072     'expGrowth',     []; ...
    +0073     'foldChange',    []; ...
    +0074     'iterPerEnzyme', []; ...
    +0075     'modelAdapter',  []; ...
    +0076     'verbose',       []});
    +0077 expGrowth     = p.expGrowth;
    +0078 foldChange    = p.foldChange;
    +0079 iterPerEnzyme = p.iterPerEnzyme;
    +0080 modelAdapter  = p.modelAdapter;
    +0081 verbose       = p.verbose;
    +0082 
    +0083 if isempty(verbose)
    +0084     verbose = true;
    +0085 end
    +0086 if isempty(modelAdapter)
    +0087     modelAdapter = ModelAdapterManager.getDefault();
    +0088     if isempty(modelAdapter)
    +0089         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0090     end
    +0091 end
    +0092 params = modelAdapter.getParameters();
    +0093 
    +0094 if isempty(iterPerEnzyme)
    +0095     iterPerEnzyme = 5;
    +0096 end
    +0097 
    +0098 if isempty(foldChange)
    +0099     foldChange = 2;
    +0100 end
    +0101 
    +0102 if isempty(expGrowth)
    +0103     expGrowth = modelAdapter.getParameters().gR_exp;
    +0104 end
    +0105 
    +0106 % If a zero value is defined, not iteration limit will be set
    +0107 if iterPerEnzyme == 0
    +0108     iterPerEnzyme = inf;
    +0109 end
    +0110 
    +0111 bioRxnIdx = getIndexes(model,params.bioRxn,'rxns');
    +0112 if model.ub(bioRxnIdx) < expGrowth
    +0113     fprintf(['The upper bound of the biomass reaction was %s, while expGrowth '...
    +0114              'is %s. The upper bound has been set to expGrowth.'],...
    +0115              num2str(model.ub(bioRxnIdx)), num2str(expGrowth))
    +0116     model.ub(bioRxnIdx) = expGrowth;
    +0117 end
    +0118 
    +0119 % Keep track if protein pool will be flexibilized
    +0120 changedProtPool = false;
    +0121 
    +0122 % In case the model have not been protein constrained
    +0123 % model = constrainEnzConcs(model);
    +0124 
    +0125 [sol,hs] = solveLP(model);
    +0126 predGrowth = sol.f;
    +0127 
    +0128 % Get those proteins with a concentration defined
    +0129 protConcs = find(~isnan(model.ec.concs));
    +0130 
    +0131 % Get enzymes names with a concentration value
    +0132 proteins = model.ec.enzymes(protConcs);
    +0133 
    +0134 % Store how many time is predicted a enzyme with the highest coeff
    +0135 frequence = zeros(numel(proteins),1);
    +0136 
    +0137 flexBreak=false;
    +0138 if any(protConcs)
    +0139     while predGrowth < expGrowth
    +0140 
    +0141         % Get the control coefficients
    +0142         [~, controlCoeffs] = getConcControlCoeffs(model, proteins, foldChange, 0.75);
    +0143 
    +0144         % Stop looking for limiting proteins all coeffs are zero
    +0145         if any(controlCoeffs)
    +0146 
    +0147             % Find the maximum coefficient index
    +0148             [~,maxIdx] = max(controlCoeffs);
    +0149 
    +0150             % Increase +1 the frequence
    +0151             frequence(maxIdx) = frequence(maxIdx) + 1;
    +0152 
    +0153             % Allow to increase the UB maximum five times
    +0154             if frequence(maxIdx) <= iterPerEnzyme
    +0155 
    +0156                 % Set how much will increase the UB
    +0157                 increase = foldChange*frequence(maxIdx);
    +0158 
    +0159                 % Get usage rxn for the highest coeff
    +0160                 protUsageIdx = strcmpi(model.rxns, strcat('usage_prot_', proteins(maxIdx)));
    +0161 
    +0162                 % replace the UB
    +0163                 model.ub(protUsageIdx) = model.ec.concs(protConcs(maxIdx)) * (1+increase);
    +0164 
    +0165                 % Get the new growth rate
    +0166                 sol = solveLP(model,0,[],hs);
    +0167                 predGrowth = sol.f;
    +0168 
    +0169                 if verbose
    +0170                     disp(['Protein ' proteins{maxIdx} ' UB adjusted. Grow: ' num2str(predGrowth)])
    +0171                 end
    +0172             else
    +0173                 printOrange(['WARNING: Limit has been reached. Protein '  proteins{maxIdx} ' seems to be problematic. Consider changing the kcat.\n']);
    +0174                 flexBreak=true;
    +0175                 break
    +0176             end
    +0177         else
    +0178             disp('No (more) limiting enzymes have been found. Attempting to increase protein pool exchange...')
    +0179             protPoolIdx = getIndexes(model,'prot_pool_exchange','rxns');
    +0180             oldProtPool = model.ub(protPoolIdx);
    +0181             tempModel = setParam(model,'ub',protPoolIdx,1000);
    +0182             tempModel = setParam(tempModel,'ub',bioRxnIdx,expGrowth);
    +0183             sol = solveLP(tempModel);
    +0184             if (sol.f-predGrowth)>1e-3 % There is improvement in growth rate
    +0185                 % Find new protein pool constraint
    +0186                 predGrowth = sol.f;
    +0187                 tempModel = setParam(tempModel,'lb',bioRxnIdx,predGrowth);
    +0188                 % minimise pool usage (solveLP maximises the objective, so use -1)
    +0189                 tempModel = setParam(tempModel,'obj',protPoolIdx,-1);
    +0190                 sol = solveLP(tempModel);
    +0191                 newProtPool = sol.x(protPoolIdx);
    +0192                 model.ub(protPoolIdx) = newProtPool;
    +0193                 fprintf(['Changing the upper bound of protein pool exchange from %s ',...
    +0194                          'to %s enabled a\ngrowth rate of %s. It can be helpful to set ', ...
    +0195                          'the upper bound of protein\npool exchange to 1000 before ',...
    +0196                          'running flexibilizeEnzConcs.\n'],num2str(oldProtPool), ...
    +0197                          num2str(newProtPool),num2str(predGrowth));
    +0198                 changedProtPool = true;
    +0199             else
    +0200                 fprintf(['Protein pool exchange was also not limiting. Inability to reach growth ',...
    +0201                         'rate is not related to\nenzyme constraints. Maximum growth rate ',...
    +0202                         'is %s.\n'], num2str(predGrowth))
    +0203             end
    +0204             % To return an usable model with these conditions, set the
    +0205             % highest growth rate reached as the experimental value
    +0206             expGrowth = predGrowth;
    +0207             break
    +0208         end
    +0209     end
    +0210 else
    +0211     error('Protein concentrations have not been defined. Please run readProteomics and constrainEnzConcs')
    +0212 end
    +0213 
    +0214 protFlex         = proteins(frequence>0);
    +0215 [~,protUsageIdx] = ismember(strcat('usage_prot_', protFlex), model.rxns);
    +0216 [~,ecProtId]     = ismember(protFlex, model.ec.enzymes);
    +0217 oldConcs         = model.ec.concs(ecProtId);
    +0218 %frequence        = frequence(ecProtId);
    +0219 
    +0220 if flexBreak == false && ~isempty(protFlex)
    +0221     % Not all flexibilized proteins require flexibilization in the end
    +0222     % Test flux distribution with minimum prot_pool usage
    +0223     modelTemp       = setParam(model,'var',params.bioRxn,expGrowth,0.5);
    +0224     % minimise pool usage (solveLP maximises the objective, so use -1)
    +0225     modelTemp       = setParam(modelTemp,'obj','prot_pool_exchange',-1);
    +0226     sol             = solveLP(modelTemp,1);
    +0227     % Check which concentrations can remain unchanged
    +0228     newConcs        = abs(sol.x(protUsageIdx));
    +0229     keepOld         = newConcs<oldConcs;
    +0230     % Set UBs
    +0231     model.ub(protUsageIdx(keepOld))  = oldConcs(keepOld);
    +0232     model.ub(protUsageIdx(~keepOld)) = newConcs(~keepOld);
    +0233     % Output structure
    +0234     protFlex(keepOld) = [];
    +0235     oldConcs(keepOld) = [];
    +0236     newConcs(keepOld) = [];
    +0237     frequence=frequence(frequence>0);
    +0238     frequence(keepOld) = [];
    +0239     
    +0240     flexEnz.uniprotIDs = protFlex;
    +0241     flexEnz.oldConcs   = oldConcs;
    +0242     flexEnz.flexConcs  = newConcs;
    +0243     flexEnz.frequence  = frequence(frequence>0);
    +0244 else
    +0245     protFlex           = proteins(frequence>0);
    +0246     [~, protUsageIdx]  = ismember(strcat('usage_prot_', protFlex), model.rxns);
    +0247 
    +0248     flexEnz.uniprotIDs = protFlex;
    +0249     flexEnz.oldConcs   = model.ec.concs(ecProtId);
    +0250     flexEnz.flexConcs  = model.ub(protUsageIdx);
    +0251     flexEnz.frequence  = frequence(frequence>0);
    +0252 end
    +0253 if changedProtPool
    +0254     flexEnz.uniprotIDs(end+1) = {'prot_pool'};
    +0255     flexEnz.oldConcs(end+1)   = oldProtPool;
    +0256     flexEnz.flexConcs(end+1)  = newProtPool;
    +0257     flexEnz.frequence(end+1)  = 1;
    +0258 end
    +0259 % Sort by biggest ratio increase
    +0260 flexEnz.ratioIncr  = flexEnz.flexConcs./flexEnz.oldConcs;
    +0261 [~,b] = sort(flexEnz.ratioIncr,'descend');
    +0262 flexEnz.ratioIncr  = flexEnz.ratioIncr(b);
    +0263 flexEnz.uniprotIDs = flexEnz.uniprotIDs(b);
    +0264 flexEnz.oldConcs   = flexEnz.oldConcs(b);
    +0265 flexEnz.flexConcs  = flexEnz.flexConcs(b);
    +0266 flexEnz.frequence  = flexEnz.frequence(b);
    +0267 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/limit_proteins/getConcControlCoeffs.html b/doc/src/limit_proteins/getConcControlCoeffs.html new file mode 100644 index 00000000..c9ad2e55 --- /dev/null +++ b/doc/src/limit_proteins/getConcControlCoeffs.html @@ -0,0 +1,203 @@ + + + + Description of getConcControlCoeffs + + + + + + + + + +
    Home > src > limit_proteins > getConcControlCoeffs.m
    + + + +

    getConcControlCoeffs +

    + +

    PURPOSE ^

    +
    getConcControlCoeffs Calculate control coefficients of protein usage.
    + +

    SYNOPSIS ^

    +
    function [enz, controlCoeffs] = getConcControlCoeffs(model, varargin)
    + +

    DESCRIPTION ^

    +
     getConcControlCoeffs  Calculate control coefficients of protein usage.
    +
    + For each candidate protein whose usage reaction is running above the
    + given limit fraction of its upper bound, temporarily increases that
    + protein's usage upper bound by foldChange, re-solves, and expresses the
    + resulting growth-rate increase per unit of concentration increase as a
    + control coefficient. Proteins below the limit, or whose increase does
    + not measurably raise growth, get a coefficient of zero.
    +
    + Parameters
    + ----------
    + model : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + proteins : cell
    +     a list of proteins to calculate the coefficients (default
    +     model.ec.enzymes).
    + foldChange : double
    +     a value how much to increase the protein concentration (default 2).
    + limit : double
    +     threshold on the usage/concentration ratio (how saturated a
    +     protein's usage upper bound already is); only proteins with a ratio
    +     above this value are evaluated for a control coefficient (default
    +     0, i.e. any nonzero usage is evaluated).
    +
    + Returns
    + -------
    + enz : logical
    +     flags which of the input proteins had a usage/concentration ratio
    +     above limit and were evaluated for a control coefficient.
    + controlCoeffs : double
    +     control coefficient per input protein (0 for proteins not evaluated
    +     or whose increase did not measurably raise growth).
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     [enz, controlCoeffs] = getConcControlCoeffs(model);
    +     [enz, controlCoeffs] = getConcControlCoeffs(model, 'foldChange', 3);
    +
    + See also
    + --------
    + flexibilizeEnzConcs
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: + + + + + +

    SOURCE CODE ^

    +
    0001 function [enz, controlCoeffs] = getConcControlCoeffs(model, varargin)
    +0002 % getConcControlCoeffs  Calculate control coefficients of protein usage.
    +0003 %
    +0004 % For each candidate protein whose usage reaction is running above the
    +0005 % given limit fraction of its upper bound, temporarily increases that
    +0006 % protein's usage upper bound by foldChange, re-solves, and expresses the
    +0007 % resulting growth-rate increase per unit of concentration increase as a
    +0008 % control coefficient. Proteins below the limit, or whose increase does
    +0009 % not measurably raise growth, get a coefficient of zero.
    +0010 %
    +0011 % Parameters
    +0012 % ----------
    +0013 % model : struct
    +0014 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0015 %
    +0016 % Name-Value Arguments
    +0017 % --------------------
    +0018 % proteins : cell
    +0019 %     a list of proteins to calculate the coefficients (default
    +0020 %     model.ec.enzymes).
    +0021 % foldChange : double
    +0022 %     a value how much to increase the protein concentration (default 2).
    +0023 % limit : double
    +0024 %     threshold on the usage/concentration ratio (how saturated a
    +0025 %     protein's usage upper bound already is); only proteins with a ratio
    +0026 %     above this value are evaluated for a control coefficient (default
    +0027 %     0, i.e. any nonzero usage is evaluated).
    +0028 %
    +0029 % Returns
    +0030 % -------
    +0031 % enz : logical
    +0032 %     flags which of the input proteins had a usage/concentration ratio
    +0033 %     above limit and were evaluated for a control coefficient.
    +0034 % controlCoeffs : double
    +0035 %     control coefficient per input protein (0 for proteins not evaluated
    +0036 %     or whose increase did not measurably raise growth).
    +0037 %
    +0038 % Examples
    +0039 % --------
    +0040 %     % optional arguments may be given positionally or as name-value pairs:
    +0041 %     [enz, controlCoeffs] = getConcControlCoeffs(model);
    +0042 %     [enz, controlCoeffs] = getConcControlCoeffs(model, 'foldChange', 3);
    +0043 %
    +0044 % See also
    +0045 % --------
    +0046 % flexibilizeEnzConcs
    +0047 
    +0048 p = parseGECKOargs(varargin, { ...
    +0049     'proteins',   []; ...
    +0050     'foldChange', []; ...
    +0051     'limit',      []});
    +0052 proteins   = p.proteins;
    +0053 foldChange = p.foldChange;
    +0054 limit      = p.limit;
    +0055 
    +0056 if isempty(limit)
    +0057     limit = 0;
    +0058 end
    +0059 
    +0060 if isempty(foldChange)
    +0061     foldChange = 2;
    +0062 end
    +0063 
    +0064 if isempty(proteins)
    +0065     proteins = model.ec.enzymes;
    +0066 end
    +0067 
    +0068 % for now
    +0069 enz = false(length(proteins),1);
    +0070 controlCoeffs = zeros(length(proteins),1);
    +0071 
    +0072 [sol,hs] = solveLP(model);
    +0073 initialGrowth = sol.f;
    +0074 
    +0075 % Get enzyme index
    +0076 [~, protIdx] = ismember(proteins, model.ec.enzymes);
    +0077 
    +0078 % Get the protein usage reactions
    +0079 protUsageRxns = strcat('usage_prot_', model.ec.enzymes(protIdx));
    +0080 [~, protUsageRxnIdx] = ismember(protUsageRxns, model.rxns);
    +0081 
    +0082 for i = 1:numel(proteins)
    +0083     % Get the previous concentration
    +0084     prevConc = model.ub(protUsageRxnIdx(i));
    +0085 
    +0086     % Only consider those with a usage close the UB
    +0087     if (sol.x(protUsageRxnIdx(i))/prevConc) > limit
    +0088         
    +0089         % Update the logical vector
    +0090         enz(i) = 1;
    +0091 
    +0092         % Create a temporal model since coeff will be calculated one enzyme at
    +0093         % the time, without other change
    +0094         tempModel = model;
    +0095         % Increase the concentration by flexfactor
    +0096         newConc = prevConc*(foldChange);
    +0097         tempModel.ub(protUsageRxnIdx(i)) = newConc;
    +0098 
    +0099         % Get the new growth rate after the adjustment
    +0100         [tempSol,hs] = solveLP(tempModel,0,[],hs);
    +0101         tempGrowth = tempSol.f;
    +0102         
    +0103         % Calculate the coeff only if new growth rate is significantly
    +0104         % higher than initial value
    +0105         if (tempGrowth-initialGrowth)>1e-10
    +0106             controlCoeffs(i) = (tempGrowth-initialGrowth)/(newConc-prevConc);
    +0107         end
    +0108     end
    +0109 
    +0110 end
    +0111 end
    +0112
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/limit_proteins/index.html b/doc/src/limit_proteins/index.html new file mode 100644 index 00000000..a65f38f0 --- /dev/null +++ b/doc/src/limit_proteins/index.html @@ -0,0 +1,29 @@ + + + + Index for Directory src/limit_proteins + + + + + + + + + + +
    < Master indexIndex for src/limit_proteins >
    + +

    Index for src/limit_proteins

    + +

    Matlab files in this directory:

    + +
     calculateFfactorcalculateFfactor Compute the f factor for an ecModel.
     constrainEnzConcsconstrainEnzConcs Constrain enzyme usages by their concentration.
     constrainFluxDataconstrainFluxData Constrain ecModel fluxes to provided flux data.
     fillEnzConcsfillEnzConcs Populate model.ec.concs from proteome data.
     flexibilizeEnzConcsflexibilizeEnzConcs Flexibilize enzyme concentrations of an ecModel.
     getConcControlCoeffsgetConcControlCoeffs Calculate control coefficients of protein usage.
     relaxProteomicsGreedyrelaxProteomicsGreedy Greedy shadow-price-ordered relaxation of proteomics
     updateProtPoolupdateProtPool Update the protein pool to compensate for proteomics.
    + + + + +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/limit_proteins/relaxProteomicsGreedy.html b/doc/src/limit_proteins/relaxProteomicsGreedy.html new file mode 100644 index 00000000..1be069c2 --- /dev/null +++ b/doc/src/limit_proteins/relaxProteomicsGreedy.html @@ -0,0 +1,262 @@ + + + + Description of relaxProteomicsGreedy + + + + + + + + + +
    Home > src > limit_proteins > relaxProteomicsGreedy.m
    + + + +

    relaxProteomicsGreedy +

    + +

    PURPOSE ^

    +
    relaxProteomicsGreedy Greedy shadow-price-ordered relaxation of proteomics
    + +

    SYNOPSIS ^

    +
    function result = relaxProteomicsGreedy(model, varargin)
    + +

    DESCRIPTION ^

    +
     relaxProteomicsGreedy  Greedy shadow-price-ordered relaxation of proteomics
    + constraints.
    +
    + While growth is below minimalGrowth, finds the still-proteomics-constrained
    + enzyme (usage_prot_<id> upper bound below defaultUpperBound) with the
    + largest absolute shadow price on its prot_<id> mass-balance constraint,
    + fully relaxes it back to defaultUpperBound, re-solves, and repeats.
    +
    + Parameters
    + ----------
    + model : struct
    +     a full ecModel in GECKO 3 format, with some usage_prot_<id> reactions
    +     constrained below defaultUpperBound (e.g. by constrainEnzConcs).
    +
    + Name-Value Arguments
    + --------------------
    + minimalGrowth : double
    +     target objective value. Required.
    + enzymeSet : cell
    +     subset of uniprot ids eligible for relaxation (default: every
    +     currently proteomics-constrained enzyme).
    + maxIterations : double
    +     safety cap; errors if exceeded while eligible enzymes still remained
    +     (default 100).
    + defaultUpperBound : double
    +     value to restore on a relaxed usage reaction, matching the shared-pool
    +     default makeEcModel itself sets (default 1000).
    +
    + Returns
    + -------
    + result : struct
    +     - relaxed : struct mapping each relaxed uniprot id to its original
    +       model.ec.concs value, so the caller can restore it later.
    +     - trace : struct array, one row per relaxation step, with fields
    +       iteration (0-based), relaxedUniprot, growthBefore, growthAfter,
    +       shadowPrice.
    +     - finalGrowth : objective value when the loop stopped.
    +     - converged : true iff finalGrowth >= minimalGrowth.
    +
    + Examples
    + --------
    +     result = relaxProteomicsGreedy(ecModel, 'minimalGrowth', 0.1);
    +
    + Notes
    + -----
    + Different relaxation strategy from flexibilizeEnzConcs: this one is
    + shadow-price-ordered (one solve per step) and often converges in fewer
    + iterations when one or two enzymes dominate the infeasibility. The
    + trade-off is that it fully unconstrains each picked enzyme with no
    + tighten-back pass, so the result is looser (less proteomics-faithful).
    +
    + There are two distinct non-convergence outcomes: running out of
    + eligible candidates before reaching minimalGrowth returns normally with
    + converged=false; exhausting maxIterations while candidates still
    + remained raises an error instead.
    +
    + See also
    + --------
    + flexibilizeEnzConcs, getEnzymeBottlenecks
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function result = relaxProteomicsGreedy(model, varargin)
    +0002 % relaxProteomicsGreedy  Greedy shadow-price-ordered relaxation of proteomics
    +0003 % constraints.
    +0004 %
    +0005 % While growth is below minimalGrowth, finds the still-proteomics-constrained
    +0006 % enzyme (usage_prot_<id> upper bound below defaultUpperBound) with the
    +0007 % largest absolute shadow price on its prot_<id> mass-balance constraint,
    +0008 % fully relaxes it back to defaultUpperBound, re-solves, and repeats.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % model : struct
    +0013 %     a full ecModel in GECKO 3 format, with some usage_prot_<id> reactions
    +0014 %     constrained below defaultUpperBound (e.g. by constrainEnzConcs).
    +0015 %
    +0016 % Name-Value Arguments
    +0017 % --------------------
    +0018 % minimalGrowth : double
    +0019 %     target objective value. Required.
    +0020 % enzymeSet : cell
    +0021 %     subset of uniprot ids eligible for relaxation (default: every
    +0022 %     currently proteomics-constrained enzyme).
    +0023 % maxIterations : double
    +0024 %     safety cap; errors if exceeded while eligible enzymes still remained
    +0025 %     (default 100).
    +0026 % defaultUpperBound : double
    +0027 %     value to restore on a relaxed usage reaction, matching the shared-pool
    +0028 %     default makeEcModel itself sets (default 1000).
    +0029 %
    +0030 % Returns
    +0031 % -------
    +0032 % result : struct
    +0033 %     - relaxed : struct mapping each relaxed uniprot id to its original
    +0034 %       model.ec.concs value, so the caller can restore it later.
    +0035 %     - trace : struct array, one row per relaxation step, with fields
    +0036 %       iteration (0-based), relaxedUniprot, growthBefore, growthAfter,
    +0037 %       shadowPrice.
    +0038 %     - finalGrowth : objective value when the loop stopped.
    +0039 %     - converged : true iff finalGrowth >= minimalGrowth.
    +0040 %
    +0041 % Examples
    +0042 % --------
    +0043 %     result = relaxProteomicsGreedy(ecModel, 'minimalGrowth', 0.1);
    +0044 %
    +0045 % Notes
    +0046 % -----
    +0047 % Different relaxation strategy from flexibilizeEnzConcs: this one is
    +0048 % shadow-price-ordered (one solve per step) and often converges in fewer
    +0049 % iterations when one or two enzymes dominate the infeasibility. The
    +0050 % trade-off is that it fully unconstrains each picked enzyme with no
    +0051 % tighten-back pass, so the result is looser (less proteomics-faithful).
    +0052 %
    +0053 % There are two distinct non-convergence outcomes: running out of
    +0054 % eligible candidates before reaching minimalGrowth returns normally with
    +0055 % converged=false; exhausting maxIterations while candidates still
    +0056 % remained raises an error instead.
    +0057 %
    +0058 % See also
    +0059 % --------
    +0060 % flexibilizeEnzConcs, getEnzymeBottlenecks
    +0061 
    +0062 p = parseGECKOargs(varargin, {'minimalGrowth', []; 'enzymeSet', []; ...
    +0063     'maxIterations', []; 'defaultUpperBound', []});
    +0064 minimalGrowth     = p.minimalGrowth;
    +0065 enzymeSet         = p.enzymeSet;
    +0066 maxIterations     = p.maxIterations;
    +0067 defaultUpperBound = p.defaultUpperBound;
    +0068 if isempty(minimalGrowth)
    +0069     error('relaxProteomicsGreedy: minimalGrowth is required.')
    +0070 end
    +0071 if isempty(maxIterations)
    +0072     maxIterations = 100;
    +0073 end
    +0074 if isempty(defaultUpperBound)
    +0075     defaultUpperBound = 1000;
    +0076 end
    +0077 
    +0078 if isfield(model.ec, 'geckoLight') && model.ec.geckoLight
    +0079     error(['relaxProteomicsGreedy requires a full ecModel, not gecko-light: light models have no ' ...
    +0080         'per-enzyme prot_<id> / usage_prot_<id> machinery.'])
    +0081 end
    +0082 
    +0083 usageRxns = strcat('usage_prot_', model.ec.enzymes);
    +0084 [found, usageIdx] = ismember(usageRxns, model.rxns);
    +0085 if ~all(found)
    +0086     error('Usage reactions are not defined for all enzymes. This is done by makeEcModel.')
    +0087 end
    +0088 protMets = strcat('prot_', model.ec.enzymes);
    +0089 [found, protMetIdx] = ismember(protMets, model.mets);
    +0090 if ~all(found)
    +0091     error('Cannot find prot_<id> metabolites for all enzymes. This is done by makeEcModel.')
    +0092 end
    +0093 
    +0094 if isempty(enzymeSet)
    +0095     pool = model.ec.enzymes;
    +0096 else
    +0097     pool = intersect(enzymeSet(:), model.ec.enzymes, 'stable');
    +0098 end
    +0099 [~, poolIdx] = ismember(pool, model.ec.enzymes);
    +0100 poolIdx = poolIdx(poolIdx > 0);
    +0101 candidates = poolIdx(model.ub(usageIdx(poolIdx)) < defaultUpperBound);
    +0102 
    +0103 relaxed = struct();
    +0104 trace = struct('iteration', {}, 'relaxedUniprot', {}, 'growthBefore', {}, ...
    +0105     'growthAfter', {}, 'shadowPrice', {});
    +0106 
    +0107 sol = solveLP(model);
    +0108 if sol.stat == 1
    +0109     growth = sol.f;
    +0110 else
    +0111     growth = -inf;
    +0112 end
    +0113 
    +0114 for it = 0:(maxIterations - 1)
    +0115     if growth >= minimalGrowth
    +0116         result.relaxed = relaxed;
    +0117         result.trace = trace;
    +0118         result.finalGrowth = growth;
    +0119         result.converged = true;
    +0120         return
    +0121     end
    +0122     if isempty(candidates)
    +0123         warning('relaxProteomicsGreedy: no more candidates to relax; stopping.')
    +0124         result.relaxed = relaxed;
    +0125         result.trace = trace;
    +0126         result.finalGrowth = growth;
    +0127         result.converged = false;
    +0128         return
    +0129     end
    +0130 
    +0131     shadowPrices = abs(sol.sPrice(protMetIdx(candidates)));
    +0132     [~, bestPos] = max(shadowPrices);
    +0133     targetIdx = candidates(bestPos);
    +0134     targetUniprot = model.ec.enzymes{targetIdx};
    +0135     sp = sol.sPrice(protMetIdx(targetIdx));
    +0136 
    +0137     relaxed.(matlab.lang.makeValidName(targetUniprot)) = model.ec.concs(targetIdx);
    +0138     model.ub(usageIdx(targetIdx)) = defaultUpperBound;
    +0139     candidates(candidates == targetIdx) = [];
    +0140 
    +0141     newSol = solveLP(model);
    +0142     if newSol.stat == 1
    +0143         newGrowth = newSol.f;
    +0144     else
    +0145         newGrowth = -inf;
    +0146     end
    +0147 
    +0148     trace(end+1) = struct('iteration', it, 'relaxedUniprot', targetUniprot, ...
    +0149         'growthBefore', growth, 'growthAfter', newGrowth, 'shadowPrice', sp); %#ok<AGROW>
    +0150 
    +0151     growth = newGrowth;
    +0152     sol = newSol;
    +0153 end
    +0154 
    +0155 error('relaxProteomicsGreedy: did not converge in %d iterations (final growth %.4g < target %.4g).', ...
    +0156     maxIterations, growth, minimalGrowth)
    +0157 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/limit_proteins/updateProtPool.html b/doc/src/limit_proteins/updateProtPool.html new file mode 100644 index 00000000..1bf0e4a1 --- /dev/null +++ b/doc/src/limit_proteins/updateProtPool.html @@ -0,0 +1,195 @@ + + + + Description of updateProtPool + + + + + + + + + +
    Home > src > limit_proteins > updateProtPool.m
    + + + +

    updateProtPool +

    + +

    PURPOSE ^

    +
    updateProtPool Update the protein pool to compensate for proteomics.
    + +

    SYNOPSIS ^

    +
    function ecModel = updateProtPool(ecModel, varargin)
    + +

    DESCRIPTION ^

    +
     updateProtPool  Update the protein pool to compensate for proteomics.
    +
    + Only applicable to ecModels where unmeasured enzymes draw from the
    + protein pool while measured enzymes (constrained via model.ec.concs) do
    + not: shrinks the protein pool exchange upper bound so it represents only
    + the remaining, unmeasured protein content (total protein content Ptot
    + minus the measured protein mass). For ecModels generated with GECKO
    + 3.2.0 or later, where all enzymes draw from the protein pool regardless
    + of whether they are measured, this function raises an error instead;
    + use setProtPoolSize (see
    + https://github.com/SysBioChalmers/GECKO/issues/375).
    +
    + Parameters
    + ----------
    + ecModel : struct
    +     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +
    + Name-Value Arguments
    + --------------------
    + Ptot : double
    +     total protein content in g/gDCW, overwrites the value from
    +     modelAdapter. For instance, condition-specific fluxData.Ptot from
    +     loadFluxData can be used. If nothing is provided, the modelAdapter
    +     value is used.
    + modelAdapter : ModelAdapter
    +     a loaded model adapter (default: the current default model adapter).
    +
    + Returns
    + -------
    + ecModel : struct
    +     an ecModel where the protein pool exchange reaction's upper bound
    +     has been reduced to reflect only the unmeasured protein content.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     ecModel = updateProtPool(ecModel);
    +     ecModel = updateProtPool(ecModel, 'Ptot', 0.5);
    +
    + See also
    + --------
    + setProtPoolSize, loadFluxData
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function ecModel  = updateProtPool(ecModel, varargin)
    +0002 % updateProtPool  Update the protein pool to compensate for proteomics.
    +0003 %
    +0004 % Only applicable to ecModels where unmeasured enzymes draw from the
    +0005 % protein pool while measured enzymes (constrained via model.ec.concs) do
    +0006 % not: shrinks the protein pool exchange upper bound so it represents only
    +0007 % the remaining, unmeasured protein content (total protein content Ptot
    +0008 % minus the measured protein mass). For ecModels generated with GECKO
    +0009 % 3.2.0 or later, where all enzymes draw from the protein pool regardless
    +0010 % of whether they are measured, this function raises an error instead;
    +0011 % use setProtPoolSize (see
    +0012 % https://github.com/SysBioChalmers/GECKO/issues/375).
    +0013 %
    +0014 % Parameters
    +0015 % ----------
    +0016 % ecModel : struct
    +0017 %     an ecModel in GECKO 3 format (with ecModel.ec structure).
    +0018 %
    +0019 % Name-Value Arguments
    +0020 % --------------------
    +0021 % Ptot : double
    +0022 %     total protein content in g/gDCW, overwrites the value from
    +0023 %     modelAdapter. For instance, condition-specific fluxData.Ptot from
    +0024 %     loadFluxData can be used. If nothing is provided, the modelAdapter
    +0025 %     value is used.
    +0026 % modelAdapter : ModelAdapter
    +0027 %     a loaded model adapter (default: the current default model adapter).
    +0028 %
    +0029 % Returns
    +0030 % -------
    +0031 % ecModel : struct
    +0032 %     an ecModel where the protein pool exchange reaction's upper bound
    +0033 %     has been reduced to reflect only the unmeasured protein content.
    +0034 %
    +0035 % Examples
    +0036 % --------
    +0037 %     % optional arguments may be given positionally or as name-value pairs:
    +0038 %     ecModel = updateProtPool(ecModel);
    +0039 %     ecModel = updateProtPool(ecModel, 'Ptot', 0.5);
    +0040 %
    +0041 % See also
    +0042 % --------
    +0043 % setProtPoolSize, loadFluxData
    +0044 
    +0045 p = parseGECKOargs(varargin, { ...
    +0046     'Ptot',         []; ...
    +0047     'modelAdapter', []});
    +0048 Ptot         = p.Ptot;
    +0049 modelAdapter = p.modelAdapter;
    +0050 
    +0051 % Do not run from GECKO version 3.2.0 onwards. This can be recognized by
    +0052 % prot_usage reactions that are constrained by proteomics and still draw
    +0053 % from the protein pool
    +0054 protRxns = find(startsWith(ecModel.rxns,'usage_prot_'));
    +0055 poolMetIdx = find(strcmp(ecModel.mets,'prot_pool'));
    +0056 % Selected proteins with proteomics constraints
    +0057 constProtRxns = ~(ecModel.ub(protRxns)==1000);
    +0058 % Are any still drawing from prot_pool? This is introduced in GECKO 3.2.0.
    +0059 if any(full(ecModel.S(poolMetIdx,protRxns(constProtRxns))))
    +0060     error(['In the provided ecModel, all protein usage reactions, both with ' ...
    +0061         'and without concentration constraints, draw from the protein pool. ' ...
    +0062         'This was introduced with GECKO 3.2.0. Since then, updateProtPool ' ...
    +0063         'has become obsolete, use setProtPoolSize instead to constrain the ' ...
    +0064         'total protein pool with  condition-specific total protein content. See '...
    +0065         '<a href="https://github.com/SysBioChalmers/GECKO/issues/375">here</a> ' ...
    +0066         'for more explanation.'])
    +0067 end
    +0068 
    +0069 if isempty(modelAdapter)
    +0070     modelAdapter = ModelAdapterManager.getDefault();
    +0071     if isempty(modelAdapter)
    +0072         error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.')
    +0073     end
    +0074 end
    +0075 params = modelAdapter.params;
    +0076 
    +0077 if isempty(Ptot)
    +0078     Ptot = params.Ptot;
    +0079     disp(['Total protein content used: ' num2str(Ptot) ' [g protein/gDw]'])
    +0080 end
    +0081 
    +0082 % Convert Ptot to mg/gDW if provided in g/gDCW (which is default)
    +0083 if Ptot < 1
    +0084     Ptot = Ptot * 1000;
    +0085 end
    +0086 
    +0087 Pmeas = sum(ecModel.ec.concs,'omitnan');
    +0088 if Pmeas == 0
    +0089     error('The model has not yet been populated with proteomics, as ecModel.ec.concs is empty.')
    +0090 end
    +0091 
    +0092 Pnew = (Ptot - Pmeas) * params.f;
    +0093 
    +0094 if Pnew > 0
    +0095     PoolRxnIdx = strcmp(ecModel.rxns,'prot_pool_exchange');
    +0096     ecModel.ub(PoolRxnIdx) = Pnew*params.sigma;
    +0097     sol = solveLP(ecModel);
    +0098     if isempty(sol.x)
    +0099         error(['Estimating the remaining protein pool by subtracting the ' ...
    +0100                'sum of measured enzyme concentrations (in ecModel.ec.concs) ' ...
    +0101                'from the total protein pool (Ptot) does not yield a functional ' ...
    +0102                'model.'])
    +0103     end
    +0104 else
    +0105     error('The total measured protein mass exceeds the total protein content.')
    +0106 end
    +0107 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/model_adapter/ModelAdapter.html b/doc/src/model_adapter/ModelAdapter.html new file mode 100644 index 00000000..afb2103b --- /dev/null +++ b/doc/src/model_adapter/ModelAdapter.html @@ -0,0 +1,178 @@ + + + + Description of ModelAdapter + + + + + + + + + +
    Home > src > model_adapter > ModelAdapter.m
    + + + +

    ModelAdapter +

    + +

    PURPOSE ^

    +
    ModelAdapter Abstract base class for species-specific model adapters.
    + +

    SYNOPSIS ^

    +
    This is a script file.
    + +

    DESCRIPTION ^

    +
     ModelAdapter  Abstract base class for species-specific model adapters.
    +
    + Defines the interface that every species adapter must implement and
    + provides shared default behaviour for retrieving GECKO parameters,
    + mapping model genes to UniProt, and locating reference databases.
    + Concrete subclasses override these methods for a particular organism.
    +
    + Notes
    + -----
    + - params : struct of model-specific GECKO parameters (public property).
    + - getSpontaneousReactions : abstract method that subclasses must define.
    +
    + See also
    + --------
    + ModelAdapterManager
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • ModelAdapter ModelAdapter Abstract base class for species-specific model adapters.
    +This function is called by: +
      +
    • ModelAdapter ModelAdapter Abstract base class for species-specific model adapters.
    • TomlAdapter TomlAdapter Model adapter configured by model_adapter.toml.
    • adapterTemplate KEY_CLASSNAME Template ModelAdapter to copy and adapt per organism.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 % ModelAdapter  Abstract base class for species-specific model adapters.
    +0002 %
    +0003 % Defines the interface that every species adapter must implement and
    +0004 % provides shared default behaviour for retrieving GECKO parameters,
    +0005 % mapping model genes to UniProt, and locating reference databases.
    +0006 % Concrete subclasses override these methods for a particular organism.
    +0007 %
    +0008 % Notes
    +0009 % -----
    +0010 % - params : struct of model-specific GECKO parameters (public property).
    +0011 % - getSpontaneousReactions : abstract method that subclasses must define.
    +0012 %
    +0013 % See also
    +0014 % --------
    +0015 % ModelAdapterManager
    +0016 classdef (Abstract) ModelAdapter
    +0017     methods (Abstract)
    +0018         [spont,spontRxnNames] = getSpontaneousReactions(obj,model);
    +0019     end
    +0020     methods
    +0021         %not really needed, we could access it directly. Not very nice, but practical
    +0022         function parameters = getParameters(obj)
    +0023             parameters = obj.params;
    +0024         end
    +0025 
    +0026         %This allows for changing parameters in an adapter without
    +0027         %creating a new class. May be convenient, although less clean
    +0028         %function obj = setParameters(obj, parameters)
    +0029         %    obj.mParams = parameters;
    +0030         %end
    +0031 
    +0032         %The genes returned here should match the gene id set in the parameter params.uniprot.geneIDfield
    +0033         function genes = getUniprotCompatibleGenes(obj,inGenes)
    +0034             genes = inGenes;
    +0035         end
    +0036 
    +0037         %The genes returned here should match the gene id stored in column
    +0038         %2 (databases.kegg.genes) of kegg.tsv. Override when the model
    +0039         %uses identifiers that need transformation before KEGG lookup.
    +0040         function genes = getKeggCompatibleGenes(obj,inGenes)
    +0041             genes = inGenes;
    +0042         end
    +0043 
    +0044         function uniprotIDs = getUniprotIDsFromTable(obj,modelGenes)
    +0045             conversionTable = fullfile(obj.params.path,'data','uniprotConversion.tsv');
    +0046             if exist(conversionTable,'file')
    +0047                 fID=fopen(conversionTable,'r');
    +0048                 conversionTable = textscan(fID,'%q %q','Delimiter','\t','HeaderLines',1);
    +0049                 fclose(fID);
    +0050 
    +0051                 modelIDs    = conversionTable{1,1};
    +0052                 uniprots    = conversionTable{1,2};
    +0053 
    +0054                 [a,b] = ismember(modelGenes,modelIDs);
    +0055 
    +0056                 uniprotIDs  = strings(numel(modelGenes),1);
    +0057                 uniprotIDs(a)  = uniprots(b(a));
    +0058                 disp('The model genes are matched to Uniprot via the table at data/uniprotConversion.tsv.')
    +0059             else
    +0060                 uniprotIDs = modelGenes;
    +0061             end
    +0062         end
    +0063 
    +0064         function folder = getBrendaDBFolder(obj)
    +0065             % The project's data/brenda (geckopy brenda-refresh writes
    +0066             % there) when it exists, otherwise GECKO's BRENDA release,
    +0067             % downloaded once (fetchBrendaAsset).
    +0068             folder = fullfile(obj.params.path,'data','brenda');
    +0069             if ~isfolder(folder)
    +0070                 folder = fetchBrendaAsset();
    +0071             end
    +0072         end
    +0073 
    +0074         function x = getPhylDistStructPath(obj)
    +0075             % RAVEN 3 keeps keggPhylDist.mat under src/reconstruction/kegg
    +0076             % (earlier versions of RAVEN 3 under reconstruction/kegg), RAVEN
    +0077             % 2 under external/kegg.
    +0078             ravenRoot = findRAVENroot();
    +0079             candidates = {fullfile(ravenRoot,'src','reconstruction','kegg','keggPhylDist.mat'), ...
    +0080                 fullfile(ravenRoot,'reconstruction','kegg','keggPhylDist.mat'), ...
    +0081                 fullfile(ravenRoot,'external','kegg','keggPhylDist.mat')};
    +0082             x = candidates{end};
    +0083             for i = 1:numel(candidates)
    +0084                 if isfile(candidates{i})
    +0085                     x = candidates{i};
    +0086                     break
    +0087                 end
    +0088             end
    +0089         end
    +0090 
    +0091         % Define a model-specific function in the 'code' subfolder of the
    +0092         % project folder, that can constrain the model to anaerobic
    +0093         % conditions, and refer to this function in the modelAdapter. This
    +0094         % function is used when running cmaesKcatTuning.m (via
    +0095         % evotuneScore.m) if the fluxData has anaerobic conditions.
    +0096         function ecModel = makeModelAnaerobic(obj,ecModel)
    +0097             ecModel = ecModel;
    +0098             % Example from full_tutorial:
    +0099             % ecModel = anaerobicModel_GECKO(ecModel);
    +0100         end
    +0101         % Similarly, define a function that can change protein content in
    +0102         % the biomass composition
    +0103         function ecModel = changeProteinBiomass(obj,ecModel,Ptot)
    +0104             ecModel = ecModel;
    +0105             % Example from full_tutorial:
    +0106             % ecModel = scaleBioMass(ecModel,'protein',Ptot,'carbohydrate',false);
    +0107         end
    +0108     end
    +0109 
    +0110     %To have the params public is a bit "ugly", but very practical
    +0111     %if we want to change a parameter
    +0112     properties (Access = public)
    +0113         params;
    +0114     end
    +0115 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/model_adapter/ModelAdapterManager.html b/doc/src/model_adapter/ModelAdapterManager.html new file mode 100644 index 00000000..0697b5e4 --- /dev/null +++ b/doc/src/model_adapter/ModelAdapterManager.html @@ -0,0 +1,169 @@ + + + + Description of ModelAdapterManager + + + + + + + + + +
    Home > src > model_adapter > ModelAdapterManager.m
    + + + +

    ModelAdapterManager +

    + +

    PURPOSE ^

    +
    ModelAdapterManager Resolve and cache the active ModelAdapter.
    + +

    SYNOPSIS ^

    +
    This is a script file.
    + +

    DESCRIPTION ^

    +
     ModelAdapterManager  Resolve and cache the active ModelAdapter.
    +
    + Static helper class that loads a model adapter from a file path and
    + stores a process-wide default adapter, so that GECKO functions can
    + retrieve the active adapter without it being passed explicitly.
    +
    + An adapter is loaded from model_adapter.toml (give the file or the
    + project folder; see TomlAdapter) or from an adapter class (give its .m
    + file).
    +
    + Notes
    + -----
    + All methods are static. The default adapter is held in a persistent
    + variable and shared across the whole GECKO session.
    +
    + See also
    + --------
    + ModelAdapter
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • ModelAdapterManager ModelAdapterManager Resolve and cache the active ModelAdapter.
    • TomlAdapter TomlAdapter Model adapter configured by model_adapter.toml.
    +This function is called by: + + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 % ModelAdapterManager  Resolve and cache the active ModelAdapter.
    +0002 %
    +0003 % Static helper class that loads a model adapter from a file path and
    +0004 % stores a process-wide default adapter, so that GECKO functions can
    +0005 % retrieve the active adapter without it being passed explicitly.
    +0006 %
    +0007 % An adapter is loaded from model_adapter.toml (give the file or the
    +0008 % project folder; see TomlAdapter) or from an adapter class (give its .m
    +0009 % file).
    +0010 %
    +0011 % Notes
    +0012 % -----
    +0013 % All methods are static. The default adapter is held in a persistent
    +0014 % variable and shared across the whole GECKO session.
    +0015 %
    +0016 % See also
    +0017 % --------
    +0018 % ModelAdapter
    +0019 classdef ModelAdapterManager 
    +0020     methods(Static)
    +0021         function adapter = getAdapter(adapterPath, addToMatlabPath)
    +0022             if nargin < 2
    +0023                 addToMatlabPath = true;
    +0024             end
    +0025             ModelAdapterManager.showGECKO4Notice();
    +0026 
    +0027             adapterPath = char(adapterPath);
    +0028             if isfolder(adapterPath)
    +0029                 tomlFile = fullfile(adapterPath, 'model_adapter.toml');
    +0030                 if ~isfile(tomlFile)
    +0031                     error('No model_adapter.toml found in %s.', adapterPath);
    +0032                 end
    +0033                 adapter = TomlAdapter(tomlFile);
    +0034                 return
    +0035             end
    +0036             [adapterFolder, adapterClassName, extension] = fileparts(adapterPath);
    +0037             if strcmp(extension, '.toml')
    +0038                 adapter = TomlAdapter(adapterPath);
    +0039                 return
    +0040             elseif ~strcmp(extension, '.m')
    +0041                 error(['Please provide the project folder, its model_adapter.toml, or the ' ...
    +0042                     'full path to the adapter class file, including the .m extension.']);
    +0043             else
    +0044                 s = pathsep;
    +0045                 pathStr = [s, path, s];
    +0046                 onPath = contains(pathStr, [s, adapterFolder, s], 'IgnoreCase', ispc);
    +0047                 % Check if the folder is on the path
    +0048                 if ~onPath
    +0049                     if addToMatlabPath
    +0050                         addpath(adapterFolder);
    +0051                     else
    +0052                         printOrange(['WARNING: The adapter will not be on the MATLAB path, since addToMatlabPath is false\n' ...
    +0053                                      'and it is not currently on the path. Either set addToMatlabPath to true, fix this\n'...
    +0054                                      'manually before calling this function or make sure it is in current directory (not\n'...
    +0055                                      'recommended). If the class is not reachable throughout the entire GECKO use there will\n'...
    +0056                                      'be errors throughout.\n']);
    +0057                     end
    +0058                 end
    +0059 
    +0060             end
    +0061             adapter = feval(adapterClassName);
    +0062         end
    +0063         
    +0064         function out = getDefault()
    +0065             out = ModelAdapterManager.setGetDefault();
    +0066         end
    +0067         
    +0068         function adapter = setDefault(adapterPath, addToMatlabPath)
    +0069             if nargin < 1 || isempty(adapterPath)
    +0070                 adapter = ModelAdapterManager.setGetDefault(adapterPath);
    +0071                 return
    +0072             end
    +0073             if nargin < 2
    +0074                 addToMatlabPath = true;
    +0075             end
    +0076             adapter = ModelAdapterManager.setGetDefault(ModelAdapterManager.getAdapter(adapterPath, addToMatlabPath));
    +0077         end
    +0078         
    +0079     end
    +0080     methods(Static,Access = private)
    +0081         % This is how they recommend defining static variables in Matlab
    +0082         function out = setGetDefault(val)
    +0083             persistent defaultAdapter; %will be empty initially
    +0084             if nargin
    +0085                 defaultAdapter = val;
    +0086             end
    +0087             out = defaultAdapter;
    +0088         end
    +0089 
    +0090         function showGECKO4Notice()
    +0091             % Remove this method (and its call in getAdapter) in a future
    +0092             % GECKO 4.x release, once users have had time to notice the
    +0093             % backward-incompatible changes from GECKO 3.
    +0094             persistent shown;
    +0095             if isempty(shown)
    +0096                 printOrange(['NOTE: This is GECKO 4, which is not fully backward-compatible\n' ...
    +0097                     'with GECKO 3. See https://gecko-docs.readthedocs.io/en/latest/gecko3-to-gecko4.html\n' ...
    +0098                     'for what changed and how to stay on GECKO 3 (v3.2.5) if needed.\n']);
    +0099                 shown = true;
    +0100             end
    +0101         end
    +0102     end
    +0103 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/model_adapter/TomlAdapter.html b/doc/src/model_adapter/TomlAdapter.html new file mode 100644 index 00000000..7950999f --- /dev/null +++ b/doc/src/model_adapter/TomlAdapter.html @@ -0,0 +1,191 @@ + + + + Description of TomlAdapter + + + + + + + + + +
    Home > src > model_adapter > TomlAdapter.m
    + + + +

    TomlAdapter +

    + +

    PURPOSE ^

    +
    TomlAdapter Model adapter configured by model_adapter.toml.
    + +

    SYNOPSIS ^

    +
    This is a script file.
    + +

    DESCRIPTION ^

    +
     TomlAdapter  Model adapter configured by model_adapter.toml.
    +
    + The model adapter for a project whose parameters are in
    + model_adapter.toml, the configuration file that GECKO and geckopy share.
    + No adapter class has to be written: what used to be code in an adapter
    + class is set in the TOML file.
    +
    + - Spontaneous reactions: [spontaneous] name_contains (reactions whose
    +   name contains the text) and/or file (a TSV of reaction identifiers,
    +   optionally with a second 0/1 column).
    + - Anaerobic conditions and protein content during kcat tuning:
    +   [matlab] make_model_anaerobic and change_protein_biomass name MATLAB
    +   functions, for instance in the project's code folder, which is added
    +   to the MATLAB path. Each takes the ecModel (and, for
    +   change_protein_biomass, the protein content) and returns the ecModel.
    +
    + A project that needs other custom code can keep an adapter class and
    + read its parameters from the TOML file in its constructor:
    +
    +     obj.params = loadAdapterParams(fullfile(projectPath,'model_adapter.toml'));
    +
    + Examples
    + --------
    +     adapter = TomlAdapter(fullfile(projectPath,'model_adapter.toml'));
    +     % or, as the default adapter:
    +     ModelAdapterManager.setDefault(projectPath);
    +
    + See also
    + --------
    + ModelAdapter, ModelAdapterManager, loadAdapterParams, convertAdapterToToml
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • ModelAdapter ModelAdapter Abstract base class for species-specific model adapters.
    • TomlAdapter TomlAdapter Model adapter configured by model_adapter.toml.
    • loadAdapterParams loadAdapterParams Read model adapter parameters from a TOML file.
    +This function is called by: +
      +
    • ModelAdapterManager ModelAdapterManager Resolve and cache the active ModelAdapter.
    • TomlAdapter TomlAdapter Model adapter configured by model_adapter.toml.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 % TomlAdapter  Model adapter configured by model_adapter.toml.
    +0002 %
    +0003 % The model adapter for a project whose parameters are in
    +0004 % model_adapter.toml, the configuration file that GECKO and geckopy share.
    +0005 % No adapter class has to be written: what used to be code in an adapter
    +0006 % class is set in the TOML file.
    +0007 %
    +0008 % - Spontaneous reactions: [spontaneous] name_contains (reactions whose
    +0009 %   name contains the text) and/or file (a TSV of reaction identifiers,
    +0010 %   optionally with a second 0/1 column).
    +0011 % - Anaerobic conditions and protein content during kcat tuning:
    +0012 %   [matlab] make_model_anaerobic and change_protein_biomass name MATLAB
    +0013 %   functions, for instance in the project's code folder, which is added
    +0014 %   to the MATLAB path. Each takes the ecModel (and, for
    +0015 %   change_protein_biomass, the protein content) and returns the ecModel.
    +0016 %
    +0017 % A project that needs other custom code can keep an adapter class and
    +0018 % read its parameters from the TOML file in its constructor:
    +0019 %
    +0020 %     obj.params = loadAdapterParams(fullfile(projectPath,'model_adapter.toml'));
    +0021 %
    +0022 % Examples
    +0023 % --------
    +0024 %     adapter = TomlAdapter(fullfile(projectPath,'model_adapter.toml'));
    +0025 %     % or, as the default adapter:
    +0026 %     ModelAdapterManager.setDefault(projectPath);
    +0027 %
    +0028 % See also
    +0029 % --------
    +0030 % ModelAdapter, ModelAdapterManager, loadAdapterParams, convertAdapterToToml
    +0031 classdef TomlAdapter < ModelAdapter
    +0032     methods
    +0033         function obj = TomlAdapter(tomlFile)
    +0034             % TomlAdapter  Load the adapter from model_adapter.toml.
    +0035             %
    +0036             % Parameters
    +0037             % ----------
    +0038             % tomlFile : char
    +0039             %     path to model_adapter.toml, or to the project folder that
    +0040             %     holds it.
    +0041             obj.params = loadAdapterParams(tomlFile);
    +0042             codeFolder = fullfile(obj.params.path, 'code');
    +0043             if isfolder(codeFolder)
    +0044                 addpath(codeFolder);
    +0045             end
    +0046         end
    +0047 
    +0048         function [spont,spontRxnNames] = getSpontaneousReactions(obj,model)
    +0049             % getSpontaneousReactions  Reactions set as spontaneous in [spontaneous].
    +0050             %
    +0051             % Returns
    +0052             % -------
    +0053             % spont : logical
    +0054             %     true for each reaction of model that is spontaneous.
    +0055             % spontRxnNames : cell
    +0056             %     identifiers of those reactions.
    +0057             spont = false(numel(model.rxns),1);
    +0058             if isfield(obj.params,'spontaneous')
    +0059                 s = obj.params.spontaneous;
    +0060                 if isfield(s,'name_contains') && ~isempty(s.name_contains)
    +0061                     spont = spont | contains(model.rxnNames, s.name_contains);
    +0062                 end
    +0063                 if isfield(s,'file') && ~isempty(s.file)
    +0064                     spont = spont | ismember(model.rxns, readSpontaneousFile(s.file));
    +0065                 end
    +0066             end
    +0067             spontRxnNames = model.rxns(spont);
    +0068         end
    +0069 
    +0070         function ecModel = makeModelAnaerobic(obj,ecModel)
    +0071             % makeModelAnaerobic  Run the function named in [matlab] make_model_anaerobic.
    +0072             fun = hookName(obj, 'makeModelAnaerobic');
    +0073             if ~isempty(fun)
    +0074                 ecModel = feval(fun, ecModel);
    +0075             end
    +0076         end
    +0077 
    +0078         function ecModel = changeProteinBiomass(obj,ecModel,Ptot)
    +0079             % changeProteinBiomass  Run the function named in [matlab] change_protein_biomass.
    +0080             fun = hookName(obj, 'changeProteinBiomass');
    +0081             if ~isempty(fun)
    +0082                 ecModel = feval(fun, ecModel, Ptot);
    +0083             end
    +0084         end
    +0085     end
    +0086 end
    +0087 
    +0088 function fun = hookName(obj, field)
    +0089 fun = '';
    +0090 if isfield(obj.params,'matlab') && isfield(obj.params.matlab, field)
    +0091     fun = obj.params.matlab.(field);
    +0092 end
    +0093 end
    +0094 
    +0095 function rxns = readSpontaneousFile(file)
    +0096 % Reaction identifiers in the first column; with a second column, only
    +0097 % rows where it is 1 or true. The first row is a header.
    +0098 fid = fopen(file, 'r');
    +0099 if fid < 0
    +0100     error('GECKO:TomlAdapter', 'Cannot read the spontaneous reactions file %s', file);
    +0101 end
    +0102 header = fgetl(fid);
    +0103 nCols = numel(strsplit(header, '\t'));
    +0104 if nCols >= 2
    +0105     cols = textscan(fid, ['%q %q' repmat(' %*q', 1, nCols-2)], 'Delimiter', '\t');
    +0106     keep = ismember(lower(strtrim(cols{2})), {'1','true'});
    +0107     rxns = cols{1}(keep);
    +0108 else
    +0109     cols = textscan(fid, '%q', 'Delimiter', '\t');
    +0110     rxns = cols{1};
    +0111 end
    +0112 fclose(fid);
    +0113 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/model_adapter/adapterTemplate.html b/doc/src/model_adapter/adapterTemplate.html new file mode 100644 index 00000000..a80cae29 --- /dev/null +++ b/doc/src/model_adapter/adapterTemplate.html @@ -0,0 +1,210 @@ + + + + Description of adapterTemplate + + + + + + + + + +
    Home > src > model_adapter > adapterTemplate.m
    + + + +

    adapterTemplate +

    + +

    PURPOSE ^

    +
    KEY_CLASSNAME Template ModelAdapter to copy and adapt per organism.
    + +

    SYNOPSIS ^

    +
    This is a script file.
    + +

    DESCRIPTION ^

    +
     KEY_CLASSNAME  Template ModelAdapter to copy and adapt per organism.
    +
    + Starting point for a species-specific adapter. Copy this file, rename
    + the class, and edit the parameter values set in the constructor and the
    + getSpontaneousReactions method to match the target organism and model.
    +
    + See also
    + --------
    + ModelAdapter, ModelAdapterManager
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • ModelAdapter ModelAdapter Abstract base class for species-specific model adapters.
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 % KEY_CLASSNAME  Template ModelAdapter to copy and adapt per organism.
    +0002 %
    +0003 % Starting point for a species-specific adapter. Copy this file, rename
    +0004 % the class, and edit the parameter values set in the constructor and the
    +0005 % getSpontaneousReactions method to match the target organism and model.
    +0006 %
    +0007 % See also
    +0008 % --------
    +0009 % ModelAdapter, ModelAdapterManager
    +0010 classdef KEY_CLASSNAME < ModelAdapter
    +0011     methods
    +0012         function obj = KEY_CLASSNAME()
    +0013             % KEY_CLASSNAME  Construct the adapter and set default parameters.
    +0014             %
    +0015             % Sets initial values of obj.params; they can be changed by
    +0016             % the user after construction.
    +0017             %
    +0018             % Returns
    +0019             % -------
    +0020             % obj : ModelAdapter
    +0021             %     the constructed adapter instance.
    +0022 
    +0023             % Directory where all model-specific files and scripts are kept.
    +0024             % Is assumed to follow the GECKO-defined folder structure.
    +0025             obj.params.path = fullfile('KEY_PATH', 'KEY_NAME');
    +0026             addpath(fullfile(obj.params.path,'code'));
    +0027 
    +0028             % Path to the conventional GEM that this ecModel will be based on.
    +0029             obj.params.convGEM = fullfile(obj.params.path,'models','yourModel.xml');
    +0030 
    +0031             % Average enzyme saturation factor
    +0032             obj.params.sigma = 0.5;
    +0033 
    +0034             % Total protein content in the cell [g protein/gDw]
    +0035             obj.params.Ptot = 0.5;
    +0036 
    +0037             % Fraction of enzymes in the model [g enzyme/g protein]
    +0038             obj.params.f = 0.5;
    +0039             
    +0040             % Growth rate the model should be able to reach when not
    +0041             % constraint by nutrient uptake (e.g. max growth rate) [1/h]
    +0042             obj.params.gR_exp = 0.41;
    +0043 
    +0044             % Provide your organism scientific name
    +0045             obj.params.org_name = 'genus species';
    +0046 
    +0047             % Which BRENDA aggregate fuzzyKcatMatching reads for each
    +0048             % (EC, substrate, organism) triple: 'max' (the highest
    +0049             % turnover reported) or 'median' (the middle one). Can also
    +0050             % be given per call as
    +0051             % fuzzyKcatMatching(model,'kcatAggregation','median').
    +0052             obj.params.kcatAggregation = 'max';
    +0053             
    +0054             % Taxonomic identifier for Complex Portal
    +0055             obj.params.complex.taxonomicID = [];
    +0056 
    +0057             % Provide your organism KEGG ID, selected at
    +0058             % https://www.genome.jp/kegg/catalog/org_list.html
    +0059             obj.params.kegg.ID = 'sce';
    +0060             % Field for KEGG gene identifier; should match the gene
    +0061             % identifiers used in the model. With 'kegg', it takes the
    +0062             % default KEGG Entry identifier (for example YER023W here:
    +0063             % https://www.genome.jp/dbget-bin/www_bget?sce:YER023W).
    +0064             % Alternatively, gene identifiers from the "Other DBs" section
    +0065             % of the KEGG page can be selected. For example "NCBI-GeneID",
    +0066             % "UniProt", or "Ensembl". Not all DB entries are available for
    +0067             % all organisms and/or genes.
    +0068             obj.params.kegg.geneID = 'kegg';
    +0069 
    +0070             % Provide what identifier should be used to query UniProt.
    +0071             % Select proteome IDs at https://www.uniprot.org/proteomes/
    +0072             % or taxonomy IDs at https://www.uniprot.org/taxonomy.
    +0073             obj.params.uniprot.type = 'taxonomy'; % 'proteome' or 'taxonomy'
    +0074             obj.params.uniprot.ID = '559292'; % should match the ID type
    +0075             % Field for Uniprot gene ID - should match the gene ids used in the
    +0076             % model. It should be one of the "Returned Field" entries under
    +0077             % "Names & Taxonomy" at this page: https://www.uniprot.org/help/return_fields
    +0078             obj.params.uniprot.geneIDfield = 'gene_oln';
    +0079             % Whether only reviewed data from UniProt should be considered.
    +0080             % Reviewed data has highest confidence, but coverage might be (very)
    +0081             % low for non-model organisms
    +0082             obj.params.uniprot.reviewed = false;
    +0083 
    +0084             % Reaction ID for glucose exchange reaction (or other preferred carbon source)
    +0085             obj.params.c_source = 'r_1714'; 
    +0086 
    +0087             % Reaction ID for biomass pseudoreaction
    +0088             obj.params.bioRxn = 'r_4041';
    +0089 
    +0090             % Name of the compartment where the protein pseudometabolites
    +0091             % should be located (all be located in the same compartment,
    +0092             % this does not interfere with them catalyzing reactions in
    +0093             % different compartments). Typically, cytoplasm is chosen.
    +0094             obj.params.enzyme_comp = 'cytoplasm';
    +0095 
    +0096             %% Hyperparameters for evotune (CMA-ES) kcat fitting
    +0097             % Default initial uncertainty (standard deviation in log-space) for kcat values
    +0098             obj.params.evotune.sigma0logDefault    = 0.5;
    +0099             % Data sources for kcat values, ordered from least to most trusted
    +0100             obj.params.evotune.kcatSources         = {'dlkcat','brenda','custom'};
    +0101             % Initial uncertainty for each source (lower = more trusted data)
    +0102             obj.params.evotune.sigma0logSource     = [0.4; 0.2; 0.1];
    +0103 
    +0104             % Weight on the max-growth RMSE against the flux RMSE:
    +0105             % (rmseFlux + w*rmseMaxGrowth) / (w+1). At 1 both count equally.
    +0106             obj.params.evotune.maxGrowthWeight     = 1.0;
    +0107             % Weight on a prior term in the search objective,
    +0108             % rmse + w*mean((log(k/k0)/sigma0log)^2). Keeps large corrections
    +0109             % reproducible across seeds; 0 scores on RMSE alone.
    +0110             obj.params.evotune.priorPenaltyWeight  = 0.03;
    +0111             % Give isozyme copies of one reaction (sharing a prior value and
    +0112             % a source) a single shared kcat, so the search cannot invent a
    +0113             % distinction the kcat assignment never made.
    +0114             obj.params.evotune.tieIsozymes         = true;
    +0115 
    +0116             % Stop optimization when RMSE falls below this threshold
    +0117             obj.params.evotune.rmseThreshold       = 0.2;
    +0118             % Maximum number of CMA-ES generations before termination
    +0119             obj.params.evotune.maxGenerations      = 150;
    +0120         end
    +0121 
    +0122         % function ecModel = makeModelAnaerobic(ecModel)
    +0123         %     % Define a model-specific function in the 'code' subfolder,
    +0124         %     % that can constrain the model to anaerobic conditions, and
    +0125         %     % include the name of this function here. This is used by
    +0126         %     % cmaesKcatTuning.m (via evotuneScore.m) if the fluxData
    +0127         %     % has anaerobic conditions.
    +0128         %     addpath(fullfile(obj.params.path,'code'));
    +0129         %     ecModel = nameOfModelSpecificFunction(ecModel);
    +0130         % end
    +0131 
    +0132         function [spont,spontRxnNames] = getSpontaneousReactions(obj,model)
    +0133             % getSpontaneousReactions  Identify spontaneous reactions in the model.
    +0134             %
    +0135             % Indicates how spontaneous reactions are identified. Here it
    +0136             % is done by the reaction having 'spontaneous' in its name.
    +0137             %
    +0138             % Parameters
    +0139             % ----------
    +0140             % model : struct
    +0141             %     a model in RAVEN format.
    +0142             %
    +0143             % Returns
    +0144             % -------
    +0145             % spont : logical
    +0146             %     true for each reaction identified as spontaneous.
    +0147             % spontRxnNames : cell
    +0148             %     names of the reactions identified as spontaneous.
    +0149             spont = contains(model.rxnNames,'spontaneous');
    +0150             spontRxnNames = model.rxnNames(spont);
    +0151         end
    +0152     end
    +0153 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/model_adapter/convertAdapterToToml.html b/doc/src/model_adapter/convertAdapterToToml.html new file mode 100644 index 00000000..7477b31f --- /dev/null +++ b/doc/src/model_adapter/convertAdapterToToml.html @@ -0,0 +1,316 @@ + + + + Description of convertAdapterToToml + + + + + + + + + +
    Home > src > model_adapter > convertAdapterToToml.m
    + + + +

    convertAdapterToToml +

    + +

    PURPOSE ^

    +
    convertAdapterToToml Write the parameters of an adapter class to model_adapter.toml.
    + +

    SYNOPSIS ^

    +
    function report = convertAdapterToToml(adapter, tomlFile)
    + +

    DESCRIPTION ^

    +
     convertAdapterToToml  Write the parameters of an adapter class to model_adapter.toml.
    +
    + Converts an existing ModelAdapter class (GECKO 3 or 4 style) to
    + model_adapter.toml, the configuration file shared by GECKO and geckopy.
    + Parameter names are translated with adapterParameters.tsv (for instance
    + Ptot becomes p_tot), paths inside the project folder are written
    + relative to it, and parameters without a geckopy name are kept under
    + [matlab.params], so that loadAdapterParams gives back the same params.
    +
    + Methods that the adapter class overrides cannot be written to TOML.
    + They are listed in the report, with how to carry them over:
    + - getSpontaneousReactions: set [spontaneous] name_contains or file;
    + - makeModelAnaerobic, changeProteinBiomass: set [matlab]
    +   make_model_anaerobic or change_protein_biomass to a function name;
    + - other methods: keep the adapter class and let its constructor call
    +   loadAdapterParams.
    +
    + Parameters
    + ----------
    + adapter : ModelAdapter or char
    +     an adapter object, or the path to its .m file.
    + tomlFile : char, optional
    +     file to write (default: model_adapter.toml in the adapter's
    +     params.path). An existing file is not overwritten.
    +
    + Returns
    + -------
    + report : struct
    +     - file: the file written;
    +     - unmapped: parameters written under [matlab.params];
    +     - methods: overridden methods that need carrying over by hand.
    +
    + Examples
    + --------
    +     report = convertAdapterToToml(fullfile(projectPath,'MyGEMAdapter.m'));
    +     adapter = TomlAdapter(projectPath);
    +
    + See also
    + --------
    + TomlAdapter, loadAdapterParams, writeAdapterToml
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • writeAdapterToml writeAdapterToml Write a struct as a model adapter TOML file.
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function report = convertAdapterToToml(adapter, tomlFile)
    +0002 % convertAdapterToToml  Write the parameters of an adapter class to model_adapter.toml.
    +0003 %
    +0004 % Converts an existing ModelAdapter class (GECKO 3 or 4 style) to
    +0005 % model_adapter.toml, the configuration file shared by GECKO and geckopy.
    +0006 % Parameter names are translated with adapterParameters.tsv (for instance
    +0007 % Ptot becomes p_tot), paths inside the project folder are written
    +0008 % relative to it, and parameters without a geckopy name are kept under
    +0009 % [matlab.params], so that loadAdapterParams gives back the same params.
    +0010 %
    +0011 % Methods that the adapter class overrides cannot be written to TOML.
    +0012 % They are listed in the report, with how to carry them over:
    +0013 % - getSpontaneousReactions: set [spontaneous] name_contains or file;
    +0014 % - makeModelAnaerobic, changeProteinBiomass: set [matlab]
    +0015 %   make_model_anaerobic or change_protein_biomass to a function name;
    +0016 % - other methods: keep the adapter class and let its constructor call
    +0017 %   loadAdapterParams.
    +0018 %
    +0019 % Parameters
    +0020 % ----------
    +0021 % adapter : ModelAdapter or char
    +0022 %     an adapter object, or the path to its .m file.
    +0023 % tomlFile : char, optional
    +0024 %     file to write (default: model_adapter.toml in the adapter's
    +0025 %     params.path). An existing file is not overwritten.
    +0026 %
    +0027 % Returns
    +0028 % -------
    +0029 % report : struct
    +0030 %     - file: the file written;
    +0031 %     - unmapped: parameters written under [matlab.params];
    +0032 %     - methods: overridden methods that need carrying over by hand.
    +0033 %
    +0034 % Examples
    +0035 % --------
    +0036 %     report = convertAdapterToToml(fullfile(projectPath,'MyGEMAdapter.m'));
    +0037 %     adapter = TomlAdapter(projectPath);
    +0038 %
    +0039 % See also
    +0040 % --------
    +0041 % TomlAdapter, loadAdapterParams, writeAdapterToml
    +0042 
    +0043 if ischar(adapter) || isstring(adapter)
    +0044     adapter = ModelAdapterManager.getAdapter(char(adapter));
    +0045 end
    +0046 params = adapter.params;
    +0047 if isfield(params,'path') && isstruct(params.path)
    +0048     params.path = params.path.Name; % a struct path, as some old adapters keep it
    +0049 end
    +0050 projectPath = '';
    +0051 if isfield(params,'path')
    +0052     projectPath = char(params.path);
    +0053 end
    +0054 if nargin < 2 || isempty(tomlFile)
    +0055     tomlFile = fullfile(projectPath, 'model_adapter.toml');
    +0056 end
    +0057 if isfile(tomlFile)
    +0058     error('GECKO:convertAdapterToToml', '%s exists already; it is not overwritten.', tomlFile);
    +0059 end
    +0060 
    +0061 map = readMap();
    +0062 data = struct();
    +0063 used = {};
    +0064 for k = 1:numel(map.tomlKey)
    +0065     field = map.matlabField{k};
    +0066     if isempty(field) || any(strcmp(field, {'evotune.kcatSources','evotune.sigma0logSource'}))
    +0067         continue
    +0068     end
    +0069     [found, value] = getDotted(params, field);
    +0070     if ~found || (isempty(value) && ~ischar(value))
    +0071         if found
    +0072             used{end+1} = field; %#ok<AGROW>
    +0073         end
    +0074         continue
    +0075     end
    +0076     used{end+1} = field; %#ok<AGROW>
    +0077     if any(strcmp(map.tomlKey{k}, {'conv_gem','spontaneous.file'}))
    +0078         value = relativePath(char(value), projectPath);
    +0079     end
    +0080     data = setDotted(data, map.tomlKey{k}, value);
    +0081 end
    +0082 used{end+1} = 'path';
    +0083 
    +0084 % Trust tiers: one group per ec.source value.
    +0085 if isfield(params,'evotune') && isfield(params.evotune,'kcatSources')
    +0086     used = [used, {'evotune.kcatSources','evotune.sigma0logSource'}];
    +0087     sources = params.evotune.kcatSources;
    +0088     widths = params.evotune.sigma0logSource;
    +0089     groups = struct();
    +0090     sigma0 = struct();
    +0091     for k = 1:numel(sources)
    +0092         name = matlab.lang.makeValidName(sources{k});
    +0093         groups.(name).sources = sources(k);
    +0094         sigma0.(name) = widths(k);
    +0095     end
    +0096     data.evotune.source_groups = groups;
    +0097     data.evotune.sigma0_log_source = sigma0;
    +0098 end
    +0099 
    +0100 % Everything else is kept for GECKO under [matlab.params].
    +0101 extra = unusedFields(params, '', used);
    +0102 report.unmapped = {};
    +0103 if ~isempty(fieldnames(extra))
    +0104     data.matlab.params = extra;
    +0105     report.unmapped = flattenNames(extra, '');
    +0106 end
    +0107 
    +0108 report.methods = overriddenMethods(adapter);
    +0109 report.file = tomlFile;
    +0110 
    +0111 header = {sprintf('Model adapter for %s, converted from %s.', ...
    +0112     getOr(params,'org_name','this project'), class(adapter)), ...
    +0113     'Shared by GECKO (MATLAB) and geckopy; see adapterParameters.tsv in GECKO for every key.'};
    +0114 writeAdapterToml(data, tomlFile, header);
    +0115 
    +0116 fprintf('Wrote %s.\n', tomlFile);
    +0117 if ~isempty(report.unmapped)
    +0118     fprintf('Kept for GECKO only, under [matlab.params]: %s\n', strjoin(report.unmapped, ', '));
    +0119 end
    +0120 if ~isempty(report.methods)
    +0121     printOrange(sprintf(['%s overrides methods that a TOML file cannot hold: %s.\n' ...
    +0122         'Set [spontaneous] for getSpontaneousReactions, [matlab] function names for\n' ...
    +0123         'makeModelAnaerobic and changeProteinBiomass, or keep the class and let its\n' ...
    +0124         'constructor call loadAdapterParams.\n'], class(adapter), strjoin(report.methods, ', ')));
    +0125 end
    +0126 end
    +0127 
    +0128 function map = readMap()
    +0129 file = fullfile(fileparts(mfilename('fullpath')), 'adapterParameters.tsv');
    +0130 fid = fopen(file, 'r');
    +0131 cols = textscan(fid, '%s %s %s %s', 'Delimiter', '\t', 'HeaderLines', 1, 'Whitespace', '');
    +0132 fclose(fid);
    +0133 map.tomlKey = cols{1};
    +0134 map.matlabField = cols{2};
    +0135 end
    +0136 
    +0137 function names = overriddenMethods(adapter)
    +0138 % Methods defined by the adapter class itself rather than ModelAdapter.
    +0139 names = {};
    +0140 mc = metaclass(adapter);
    +0141 for k = 1:numel(mc.MethodList)
    +0142     m = mc.MethodList(k);
    +0143     if strcmp(m.DefiningClass.Name, mc.Name) && ~strcmp(m.Name, mc.Name) && ~m.Static
    +0144         names{end+1} = m.Name; %#ok<AGROW>
    +0145     end
    +0146 end
    +0147 names = sort(names);
    +0148 end
    +0149 
    +0150 function extra = unusedFields(s, prefix, used)
    +0151 extra = struct();
    +0152 fields = fieldnames(s);
    +0153 for k = 1:numel(fields)
    +0154     name = fields{k};
    +0155     if ~isempty(prefix)
    +0156         name = [prefix '.' name];
    +0157     end
    +0158     if any(strcmp(name, used))
    +0159         continue
    +0160     end
    +0161     value = s.(fields{k});
    +0162     if isstruct(value) && isscalar(value) && any(startsWith(used, [name '.']))
    +0163         sub = unusedFields(value, name, used);
    +0164         if ~isempty(fieldnames(sub))
    +0165             extra.(fields{k}) = sub;
    +0166         end
    +0167     elseif ~(isempty(value) && ~ischar(value) && ~iscell(value))
    +0168         extra.(fields{k}) = value;
    +0169     end
    +0170 end
    +0171 end
    +0172 
    +0173 function names = flattenNames(s, prefix)
    +0174 names = {};
    +0175 fields = fieldnames(s);
    +0176 for k = 1:numel(fields)
    +0177     name = fields{k};
    +0178     if ~isempty(prefix)
    +0179         name = [prefix '.' name];
    +0180     end
    +0181     if isstruct(s.(fields{k}))
    +0182         names = [names, flattenNames(s.(fields{k}), name)]; %#ok<AGROW>
    +0183     else
    +0184         names{end+1} = name; %#ok<AGROW>
    +0185     end
    +0186 end
    +0187 end
    +0188 
    +0189 function p = relativePath(p, projectPath)
    +0190 p = strrep(p, '\', '/');
    +0191 base = strrep(projectPath, '\', '/');
    +0192 if ~isempty(base) && startsWith(p, [base '/'])
    +0193     p = p(numel(base)+2:end);
    +0194 end
    +0195 end
    +0196 
    +0197 function [found, value] = getDotted(s, key)
    +0198 parts = strsplit(key, '.');
    +0199 value = s;
    +0200 found = true;
    +0201 for k = 1:numel(parts)
    +0202     if ~isstruct(value) || ~isfield(value, parts{k})
    +0203         found = false;
    +0204         value = [];
    +0205         return
    +0206     end
    +0207     value = value.(parts{k});
    +0208 end
    +0209 end
    +0210 
    +0211 function s = setDotted(s, key, value)
    +0212 parts = strsplit(key, '.');
    +0213 if numel(parts) == 1
    +0214     s.(parts{1}) = value;
    +0215     return
    +0216 end
    +0217 if ~isfield(s, parts{1}) || ~isstruct(s.(parts{1}))
    +0218     s.(parts{1}) = struct();
    +0219 end
    +0220 s.(parts{1}) = setDotted(s.(parts{1}), strjoin(parts(2:end), '.'), value);
    +0221 end
    +0222 
    +0223 function v = getOr(s, field, default)
    +0224 v = default;
    +0225 if isfield(s, field) && ~isempty(s.(field))
    +0226     v = s.(field);
    +0227 end
    +0228 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/model_adapter/index.html b/doc/src/model_adapter/index.html new file mode 100644 index 00000000..4845792a --- /dev/null +++ b/doc/src/model_adapter/index.html @@ -0,0 +1,29 @@ + + + + Index for Directory src/model_adapter + + + + + + + + + + +
    < Master indexIndex for src/model_adapter >
    + +

    Index for src/model_adapter

    + +

    Matlab files in this directory:

    + +
     ModelAdapterModelAdapter Abstract base class for species-specific model adapters.
     ModelAdapterManagerModelAdapterManager Resolve and cache the active ModelAdapter.
     TomlAdapterTomlAdapter Model adapter configured by model_adapter.toml.
     adapterTemplateKEY_CLASSNAME Template ModelAdapter to copy and adapt per organism.
     convertAdapterToTomlconvertAdapterToToml Write the parameters of an adapter class to model_adapter.toml.
     loadAdapterParamsloadAdapterParams Read model adapter parameters from a TOML file.
     readAdapterTomlreadAdapterToml Read a model adapter TOML file into a struct.
     writeAdapterTomlwriteAdapterToml Write a struct as a model adapter TOML file.
    + + + + +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/model_adapter/loadAdapterParams.html b/doc/src/model_adapter/loadAdapterParams.html new file mode 100644 index 00000000..53482ca9 --- /dev/null +++ b/doc/src/model_adapter/loadAdapterParams.html @@ -0,0 +1,329 @@ + + + + Description of loadAdapterParams + + + + + + + + + +
    Home > src > model_adapter > loadAdapterParams.m
    + + + +

    loadAdapterParams +

    + +

    PURPOSE ^

    +
    loadAdapterParams Read model adapter parameters from a TOML file.
    + +

    SYNOPSIS ^

    +
    function params = loadAdapterParams(tomlFile)
    + +

    DESCRIPTION ^

    +
     loadAdapterParams  Read model adapter parameters from a TOML file.
    +
    + Reads model_adapter.toml, the configuration file shared by GECKO and
    + geckopy, and returns the parameters with GECKO's field names, so that
    + they can be used as ModelAdapter.params. Keys are translated with
    + adapterParameters.tsv (for instance p_tot becomes Ptot); keys that are
    + not given get the default listed there, which is geckopy's default.
    +
    + Parameters
    + ----------
    + tomlFile : char
    +     path to model_adapter.toml, or to the project folder that holds it.
    +
    + Returns
    + -------
    + params : struct
    +     the adapter parameters, as in ModelAdapter.params:
    +     - path: the project folder (the folder of the TOML file);
    +     - convGEM and spontaneous.file: absolute paths;
    +     - evotune.kcatSources and evotune.sigma0logSource: built from the
    +       evotune.source_groups and evotune.sigma0_log_source tables, one
    +       entry per ec.source value;
    +     - fields under [matlab.params] are copied as they are, for
    +       parameters that only GECKO uses.
    +
    + Examples
    + --------
    +     params = loadAdapterParams(fullfile(projectPath,'model_adapter.toml'));
    +
    + See also
    + --------
    + TomlAdapter, readAdapterToml, convertAdapterToToml
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • readAdapterToml readAdapterToml Read a model adapter TOML file into a struct.
    +This function is called by: +
      +
    • TomlAdapter TomlAdapter Model adapter configured by model_adapter.toml.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function params = loadAdapterParams(tomlFile)
    +0002 % loadAdapterParams  Read model adapter parameters from a TOML file.
    +0003 %
    +0004 % Reads model_adapter.toml, the configuration file shared by GECKO and
    +0005 % geckopy, and returns the parameters with GECKO's field names, so that
    +0006 % they can be used as ModelAdapter.params. Keys are translated with
    +0007 % adapterParameters.tsv (for instance p_tot becomes Ptot); keys that are
    +0008 % not given get the default listed there, which is geckopy's default.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % tomlFile : char
    +0013 %     path to model_adapter.toml, or to the project folder that holds it.
    +0014 %
    +0015 % Returns
    +0016 % -------
    +0017 % params : struct
    +0018 %     the adapter parameters, as in ModelAdapter.params:
    +0019 %     - path: the project folder (the folder of the TOML file);
    +0020 %     - convGEM and spontaneous.file: absolute paths;
    +0021 %     - evotune.kcatSources and evotune.sigma0logSource: built from the
    +0022 %       evotune.source_groups and evotune.sigma0_log_source tables, one
    +0023 %       entry per ec.source value;
    +0024 %     - fields under [matlab.params] are copied as they are, for
    +0025 %       parameters that only GECKO uses.
    +0026 %
    +0027 % Examples
    +0028 % --------
    +0029 %     params = loadAdapterParams(fullfile(projectPath,'model_adapter.toml'));
    +0030 %
    +0031 % See also
    +0032 % --------
    +0033 % TomlAdapter, readAdapterToml, convertAdapterToToml
    +0034 
    +0035 if isfolder(tomlFile)
    +0036     tomlFile = fullfile(tomlFile, 'model_adapter.toml');
    +0037 end
    +0038 if ~isfile(tomlFile)
    +0039     error('GECKO:loadAdapterParams', 'No model adapter file found at %s', tomlFile);
    +0040 end
    +0041 tomlFile = char(tomlFile);
    +0042 [projectPath, ~, ~] = fileparts(getAbsolutePath(tomlFile));
    +0043 
    +0044 data = readAdapterToml(tomlFile);
    +0045 map = adapterParameterMap();
    +0046 
    +0047 % Unknown keys are errors, as in geckopy, so that a typo is not ignored.
    +0048 known = [map.tomlKey; {'evotune.source_groups'; 'evotune.sigma0_log_source'}];
    +0049 checkKnownKeys(data, '', known, tomlFile);
    +0050 
    +0051 params = struct();
    +0052 params.path = projectPath;
    +0053 for k = 1:numel(map.tomlKey)
    +0054     key = map.tomlKey{k};
    +0055     if any(strcmp(key, {'evotune.source_groups', 'evotune.sigma0_log_source'}))
    +0056         continue
    +0057     end
    +0058     [found, value] = getDotted(data, key);
    +0059     if ~found
    +0060         if isempty(map.default{k})
    +0061             continue
    +0062         end
    +0063         value = map.default{k};
    +0064     end
    +0065     if isempty(map.matlabField{k})
    +0066         field = key; % a key that only geckopy reads keeps its name
    +0067     else
    +0068         field = map.matlabField{k};
    +0069     end
    +0070     params = setDotted(params, field, value);
    +0071 end
    +0072 
    +0073 if ~isfield(params, 'complex')
    +0074     params.complex.taxonomicID = []; % geckopy's default: no Complex Portal query
    +0075 end
    +0076 
    +0077 for f = {'convGEM'}
    +0078     if isfield(params, f{1})
    +0079         params.(f{1}) = projectFile(projectPath, params.(f{1}));
    +0080     end
    +0081 end
    +0082 if isfield(params, 'spontaneous') && isfield(params.spontaneous, 'file')
    +0083     params.spontaneous.file = projectFile(projectPath, params.spontaneous.file);
    +0084 end
    +0085 
    +0086 params = sourceGroups(params, data, tomlFile);
    +0087 
    +0088 if isfield(data, 'matlab') && isfield(data.matlab, 'params')
    +0089     params = mergeStruct(params, data.matlab.params);
    +0090 end
    +0091 end
    +0092 
    +0093 function map = adapterParameterMap()
    +0094 % Reads adapterParameters.tsv into toml keys, MATLAB fields and defaults.
    +0095 file = fullfile(fileparts(mfilename('fullpath')), 'adapterParameters.tsv');
    +0096 fid = fopen(file, 'r');
    +0097 cols = textscan(fid, '%s %s %s %s', 'Delimiter', '\t', 'HeaderLines', 1, ...
    +0098     'Whitespace', '', 'ReturnOnError', false);
    +0099 fclose(fid);
    +0100 map.tomlKey = cols{1};
    +0101 map.matlabField = cols{2};
    +0102 map.default = cell(size(cols{3}));
    +0103 for k = 1:numel(cols{3})
    +0104     if ~isempty(cols{3}{k})
    +0105         map.default{k} = parseDefault(cols{3}{k});
    +0106     end
    +0107 end
    +0108 end
    +0109 
    +0110 function value = parseDefault(text)
    +0111 % A default is written as a TOML value.
    +0112 tmp = [tempname '.toml'];
    +0113 fid = fopen(tmp, 'w');
    +0114 fprintf(fid, 'x = %s\n', text);
    +0115 fclose(fid);
    +0116 cleanup = onCleanup(@() delete(tmp));
    +0117 data = readAdapterToml(tmp);
    +0118 value = data.x;
    +0119 if ischar(value) && isempty(value)
    +0120     value = '';
    +0121 end
    +0122 end
    +0123 
    +0124 function checkKnownKeys(s, prefix, known, tomlFile)
    +0125 fields = fieldnames(s);
    +0126 for k = 1:numel(fields)
    +0127     key = fields{k};
    +0128     if ~isempty(prefix)
    +0129         key = [prefix '.' key];
    +0130     end
    +0131     if strcmp(key, 'matlab.params')
    +0132         continue % free-form parameters for GECKO only
    +0133     end
    +0134     if any(strcmp(key, known)) || any(startsWith(known, [key '.']))
    +0135         if isstruct(s.(fields{k})) && ~any(strcmp(key, known))
    +0136             checkKnownKeys(s.(fields{k}), key, known, tomlFile);
    +0137         end
    +0138         continue
    +0139     end
    +0140     if any(startsWith(key, {'evotune.source_groups.', 'evotune.sigma0_log_source.'}))
    +0141         continue
    +0142     end
    +0143     error('GECKO:loadAdapterParams', ['Unknown key "%s" in %s. Parameters that only ' ...
    +0144         'GECKO uses go under [matlab.params].'], key, tomlFile);
    +0145 end
    +0146 end
    +0147 
    +0148 function params = sourceGroups(params, data, tomlFile)
    +0149 % evotune.source_groups and evotune.sigma0_log_source become the
    +0150 % kcatSources and sigma0logSource lists that evotune reads: one entry per
    +0151 % ec.source value, with its group's prior width.
    +0152 groups = struct();
    +0153 widths = struct();
    +0154 if isfield(data, 'evotune') && isfield(data.evotune, 'source_groups')
    +0155     groups = data.evotune.source_groups;
    +0156     if isfield(data.evotune, 'sigma0_log_source')
    +0157         widths = data.evotune.sigma0_log_source;
    +0158     end
    +0159 else
    +0160     % geckopy's defaults (EvotuneParams.source_groups, sigma0_log_source).
    +0161     groups.dlkcat.sources = {'dlkcat'};
    +0162     groups.brenda.sources = {'brenda'};
    +0163     groups.custom.sources = {'custom'};
    +0164     widths.dlkcat = 0.4;
    +0165     widths.brenda = 0.2;
    +0166     widths.custom = 0.1;
    +0167 end
    +0168 names = fieldnames(groups);
    +0169 if ~isempty(setxor(names, fieldnames(widths)))
    +0170     error('GECKO:loadAdapterParams', ['%s: evotune.sigma0_log_source must have ' ...
    +0171         'the same group names as evotune.source_groups'], tomlFile);
    +0172 end
    +0173 kcatSources = {};
    +0174 sigma0logSource = [];
    +0175 for k = 1:numel(names)
    +0176     group = groups.(names{k});
    +0177     sources = {};
    +0178     if isfield(group, 'sources')
    +0179         sources = group.sources;
    +0180         if ischar(sources)
    +0181             sources = {sources};
    +0182         end
    +0183     end
    +0184     if isfield(group, 'match_okp') && group.match_okp && isfield(params, 'okp')
    +0185         sources{end+1} = params.okp.method; %#ok<AGROW>
    +0186     end
    +0187     kcatSources = [kcatSources, sources]; %#ok<AGROW>
    +0188     sigma0logSource = [sigma0logSource; repmat(widths.(names{k}), numel(sources), 1)]; %#ok<AGROW>
    +0189 end
    +0190 params.evotune.kcatSources = kcatSources;
    +0191 params.evotune.sigma0logSource = sigma0logSource;
    +0192 end
    +0193 
    +0194 function [found, value] = getDotted(s, key)
    +0195 parts = strsplit(key, '.');
    +0196 value = s;
    +0197 found = true;
    +0198 for k = 1:numel(parts)
    +0199     if ~isstruct(value) || ~isfield(value, parts{k})
    +0200         found = false;
    +0201         value = [];
    +0202         return
    +0203     end
    +0204     value = value.(parts{k});
    +0205 end
    +0206 end
    +0207 
    +0208 function s = setDotted(s, key, value)
    +0209 parts = strsplit(key, '.');
    +0210 if numel(parts) == 1
    +0211     s.(parts{1}) = value;
    +0212     return
    +0213 end
    +0214 if ~isfield(s, parts{1}) || ~isstruct(s.(parts{1}))
    +0215     s.(parts{1}) = struct();
    +0216 end
    +0217 s.(parts{1}) = setDotted(s.(parts{1}), strjoin(parts(2:end), '.'), value);
    +0218 end
    +0219 
    +0220 function s = mergeStruct(s, extra)
    +0221 fields = fieldnames(extra);
    +0222 for k = 1:numel(fields)
    +0223     value = extra.(fields{k});
    +0224     if isstruct(value) && isscalar(value) && isfield(s, fields{k}) && isstruct(s.(fields{k}))
    +0225         s.(fields{k}) = mergeStruct(s.(fields{k}), value);
    +0226     else
    +0227         s.(fields{k}) = value;
    +0228     end
    +0229 end
    +0230 end
    +0231 
    +0232 function p = projectFile(projectPath, p)
    +0233 if isempty(p)
    +0234     return
    +0235 end
    +0236 if ~isAbsolute(p)
    +0237     p = fullfile(projectPath, p);
    +0238 end
    +0239 end
    +0240 
    +0241 function tf = isAbsolute(p)
    +0242 tf = startsWith(p, '/') || startsWith(p, '\') || ~isempty(regexp(p, '^[A-Za-z]:', 'once'));
    +0243 end
    +0244 
    +0245 function p = getAbsolutePath(p)
    +0246 if ~isAbsolute(p)
    +0247     p = fullfile(pwd, p);
    +0248 end
    +0249 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/model_adapter/readAdapterToml.html b/doc/src/model_adapter/readAdapterToml.html new file mode 100644 index 00000000..7ff0a18f --- /dev/null +++ b/doc/src/model_adapter/readAdapterToml.html @@ -0,0 +1,548 @@ + + + + Description of readAdapterToml + + + + + + + + + +
    Home > src > model_adapter > readAdapterToml.m
    + + + +

    readAdapterToml +

    + +

    PURPOSE ^

    +
    readAdapterToml Read a model adapter TOML file into a struct.
    + +

    SYNOPSIS ^

    +
    function data = readAdapterToml(filename)
    + +

    DESCRIPTION ^

    +
     readAdapterToml  Read a model adapter TOML file into a struct.
    +
    + Reads the subset of TOML that model adapter files use: comments, bare
    + keys, basic and literal strings, integers, floats, booleans, arrays of
    + these values (also over several lines), tables ([kegg], [a.b.c]) and
    + arrays of tables ([[a]]). Anything else, such as dates, inline tables,
    + multi-line strings or quoted keys, stops with an error that names the
    + line.
    +
    + Parameters
    + ----------
    + filename : char
    +     path to the TOML file.
    +
    + Returns
    + -------
    + data : struct
    +     one field per key, with tables as nested structs and arrays of
    +     tables as struct arrays. Strings are char, numbers double, booleans
    +     logical, arrays of strings a 1xn cell and arrays of numbers or
    +     booleans a 1xn vector. An empty array is an empty cell.
    +
    + Examples
    + --------
    +     data = readAdapterToml(fullfile(projectPath,'model_adapter.toml'));
    +
    + See also
    + --------
    + writeAdapterToml, loadAdapterParams
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • loadAdapterParams loadAdapterParams Read model adapter parameters from a TOML file.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function data = readAdapterToml(filename)
    +0002 % readAdapterToml  Read a model adapter TOML file into a struct.
    +0003 %
    +0004 % Reads the subset of TOML that model adapter files use: comments, bare
    +0005 % keys, basic and literal strings, integers, floats, booleans, arrays of
    +0006 % these values (also over several lines), tables ([kegg], [a.b.c]) and
    +0007 % arrays of tables ([[a]]). Anything else, such as dates, inline tables,
    +0008 % multi-line strings or quoted keys, stops with an error that names the
    +0009 % line.
    +0010 %
    +0011 % Parameters
    +0012 % ----------
    +0013 % filename : char
    +0014 %     path to the TOML file.
    +0015 %
    +0016 % Returns
    +0017 % -------
    +0018 % data : struct
    +0019 %     one field per key, with tables as nested structs and arrays of
    +0020 %     tables as struct arrays. Strings are char, numbers double, booleans
    +0021 %     logical, arrays of strings a 1xn cell and arrays of numbers or
    +0022 %     booleans a 1xn vector. An empty array is an empty cell.
    +0023 %
    +0024 % Examples
    +0025 % --------
    +0026 %     data = readAdapterToml(fullfile(projectPath,'model_adapter.toml'));
    +0027 %
    +0028 % See also
    +0029 % --------
    +0030 % writeAdapterToml, loadAdapterParams
    +0031 
    +0032 text = fileread(filename);
    +0033 text = strrep(text, sprintf('\r\n'), newline);
    +0034 lines = strsplit(text, newline, 'CollapseDelimiters', false);
    +0035 
    +0036 data = struct();
    +0037 tablePath = {};   % keys of the current table, each element {name, arrayIndex}
    +0038 arrayNames = {};  % dotted names declared as arrays of tables
    +0039 i = 0;
    +0040 while i < numel(lines)
    +0041     i = i + 1;
    +0042     lineNo = i;
    +0043     line = stripComment(lines{i}, filename, lineNo);
    +0044     if isempty(strtrim(line))
    +0045         continue
    +0046     end
    +0047     trimmed = strtrim(line);
    +0048     if startsWith(trimmed, '[[')
    +0049         if ~endsWith(trimmed, ']]')
    +0050             tomlError(filename, lineNo, 'array of tables header must end with ]]');
    +0051         end
    +0052         keys = splitKey(trimmed(3:end-2), filename, lineNo);
    +0053         [data, tablePath] = appendTableArray(data, keys, arrayNames, filename, lineNo);
    +0054         arrayNames = union(arrayNames, {strjoin(keys, '.')});
    +0055     elseif startsWith(trimmed, '[')
    +0056         if ~endsWith(trimmed, ']')
    +0057             tomlError(filename, lineNo, 'table header must end with ]');
    +0058         end
    +0059         keys = splitKey(trimmed(2:end-1), filename, lineNo);
    +0060         tablePath = resolvePath(data, keys, arrayNames);
    +0061         data = ensureTable(data, tablePath, filename, lineNo);
    +0062     else
    +0063         eq = findUnquoted(line, '=');
    +0064         if isempty(eq)
    +0065             tomlError(filename, lineNo, 'expected key = value');
    +0066         end
    +0067         keys = splitKey(line(1:eq-1), filename, lineNo);
    +0068         valueText = strtrim(line(eq+1:end));
    +0069         % Arrays may span several lines: read on until the brackets close.
    +0070         while startsWith(valueText, '[') && bracketDepth(valueText) > 0
    +0071             if i >= numel(lines)
    +0072                 tomlError(filename, lineNo, 'array is not closed');
    +0073             end
    +0074             i = i + 1;
    +0075             valueText = [valueText ' ' strtrim(stripComment(lines{i}, filename, i))]; %#ok<AGROW>
    +0076         end
    +0077         value = parseValue(valueText, filename, lineNo);
    +0078         data = setKey(data, [tablePath, keyPath(keys)], value, filename, lineNo);
    +0079     end
    +0080 end
    +0081 end
    +0082 
    +0083 function line = stripComment(line, filename, lineNo)
    +0084 % Removes a # comment that is not inside a string.
    +0085 inBasic = false; inLiteral = false; k = 1;
    +0086 while k <= numel(line)
    +0087     c = line(k);
    +0088     if inBasic
    +0089         if c == '\'
    +0090             k = k + 1;
    +0091         elseif c == '"'
    +0092             inBasic = false;
    +0093         end
    +0094     elseif inLiteral
    +0095         if c == ''''
    +0096             inLiteral = false;
    +0097         end
    +0098     elseif c == '"'
    +0099         if k + 2 <= numel(line) && strcmp(line(k:k+2), '"""')
    +0100             tomlError(filename, lineNo, 'multi-line strings are not supported');
    +0101         end
    +0102         inBasic = true;
    +0103     elseif c == ''''
    +0104         if k + 2 <= numel(line) && strcmp(line(k:k+2), '''''''')
    +0105             tomlError(filename, lineNo, 'multi-line strings are not supported');
    +0106         end
    +0107         inLiteral = true;
    +0108     elseif c == '#'
    +0109         line = line(1:k-1);
    +0110         return
    +0111     end
    +0112     k = k + 1;
    +0113 end
    +0114 end
    +0115 
    +0116 function idx = findUnquoted(line, ch)
    +0117 % Position of the first ch outside a string, or empty.
    +0118 idx = [];
    +0119 inBasic = false; inLiteral = false; k = 1;
    +0120 while k <= numel(line)
    +0121     c = line(k);
    +0122     if inBasic
    +0123         if c == '\'
    +0124             k = k + 1;
    +0125         elseif c == '"'
    +0126             inBasic = false;
    +0127         end
    +0128     elseif inLiteral
    +0129         if c == ''''
    +0130             inLiteral = false;
    +0131         end
    +0132     elseif c == '"'
    +0133         inBasic = true;
    +0134     elseif c == ''''
    +0135         inLiteral = true;
    +0136     elseif c == ch
    +0137         idx = k;
    +0138         return
    +0139     end
    +0140     k = k + 1;
    +0141 end
    +0142 end
    +0143 
    +0144 function depth = bracketDepth(text)
    +0145 % Open [ minus closed ] outside strings.
    +0146 depth = 0; inBasic = false; inLiteral = false; k = 1;
    +0147 while k <= numel(text)
    +0148     c = text(k);
    +0149     if inBasic
    +0150         if c == '\'
    +0151             k = k + 1;
    +0152         elseif c == '"'
    +0153             inBasic = false;
    +0154         end
    +0155     elseif inLiteral
    +0156         if c == ''''
    +0157             inLiteral = false;
    +0158         end
    +0159     elseif c == '"'
    +0160         inBasic = true;
    +0161     elseif c == ''''
    +0162         inLiteral = true;
    +0163     elseif c == '['
    +0164         depth = depth + 1;
    +0165     elseif c == ']'
    +0166         depth = depth - 1;
    +0167     end
    +0168     k = k + 1;
    +0169 end
    +0170 end
    +0171 
    +0172 function keys = splitKey(text, filename, lineNo)
    +0173 % Dotted bare key into its parts.
    +0174 keys = strtrim(strsplit(strtrim(text), '.'));
    +0175 for k = 1:numel(keys)
    +0176     if isempty(regexp(keys{k}, '^[A-Za-z][A-Za-z0-9_]*$', 'once'))
    +0177         tomlError(filename, lineNo, sprintf(['key "%s" is not supported: use letters, ' ...
    +0178             'digits and underscores, starting with a letter'], keys{k}));
    +0179     end
    +0180 end
    +0181 end
    +0182 
    +0183 function p = keyPath(keys)
    +0184 p = cellfun(@(k) {k, 0}, keys, 'UniformOutput', false);
    +0185 end
    +0186 
    +0187 function path = resolvePath(data, keys, arrayNames)
    +0188 % Path of {name, index} pairs; a key that names an array of tables refers
    +0189 % to its last element.
    +0190 path = cell(1, numel(keys));
    +0191 for k = 1:numel(keys)
    +0192     idx = 0;
    +0193     if ismember(strjoin(keys(1:k), '.'), arrayNames)
    +0194         idx = numel(getKey(data, [path(1:k-1), {{keys{k}, 0}}]));
    +0195     end
    +0196     path{k} = {keys{k}, idx};
    +0197 end
    +0198 end
    +0199 
    +0200 function [data, tablePath] = appendTableArray(data, keys, arrayNames, filename, lineNo)
    +0201 % Appends a new element to the array of tables named by keys.
    +0202 parent = resolvePath(data, keys(1:end-1), arrayNames);
    +0203 data = ensureTable(data, parent, filename, lineNo);
    +0204 name = strjoin(keys, '.');
    +0205 existing = getKey(data, [parent, {{keys{end}, 0}}]);
    +0206 if isempty(existing) || ~ismember(name, arrayNames)
    +0207     if ~isempty(existing)
    +0208         tomlError(filename, lineNo, sprintf('"%s" is already a table or value', name));
    +0209     end
    +0210     n = 1;
    +0211 else
    +0212     n = numel(existing) + 1;
    +0213 end
    +0214 tablePath = [parent, {{keys{end}, n}}];
    +0215 data = setTableElement(data, parent, keys{end}, n);
    +0216 end
    +0217 
    +0218 function data = ensureTable(data, path, filename, lineNo)
    +0219 if isempty(path)
    +0220     return
    +0221 end
    +0222 name = path{1}{1}; idx = path{1}{2};
    +0223 if ~isfield(data, name)
    +0224     data.(name) = struct();
    +0225 elseif ~isstruct(data.(name))
    +0226     tomlError(filename, lineNo, sprintf('"%s" is already a value, not a table', name));
    +0227 end
    +0228 child = data.(name);
    +0229 if idx == 0
    +0230     child = ensureTable(child, path(2:end), filename, lineNo);
    +0231     data.(name) = child;
    +0232 else
    +0233     element = child(idx);
    +0234     element = ensureTable(element, path(2:end), filename, lineNo);
    +0235     data.(name) = assignElement(child, idx, element);
    +0236 end
    +0237 end
    +0238 
    +0239 function data = setTableElement(data, parent, name, n)
    +0240 % Adds element n (an empty struct) to the table array name under parent.
    +0241 if isempty(parent)
    +0242     if ~isfield(data, name) || isempty(data.(name)) || n == 1
    +0243         data.(name) = struct();
    +0244     else
    +0245         data.(name) = assignElement(data.(name), n, struct());
    +0246     end
    +0247     return
    +0248 end
    +0249 pname = parent{1}{1}; pidx = parent{1}{2};
    +0250 child = data.(pname);
    +0251 if pidx == 0
    +0252     data.(pname) = setTableElement(child, parent(2:end), name, n);
    +0253 else
    +0254     element = setTableElement(child(pidx), parent(2:end), name, n);
    +0255     data.(pname) = assignElement(child, pidx, element);
    +0256 end
    +0257 end
    +0258 
    +0259 function value = getKey(data, path)
    +0260 value = [];
    +0261 node = data;
    +0262 for k = 1:numel(path)
    +0263     name = path{k}{1}; idx = path{k}{2};
    +0264     if ~isstruct(node) || ~isfield(node, name)
    +0265         value = [];
    +0266         return
    +0267     end
    +0268     node = node.(name);
    +0269     if idx > 0
    +0270         node = node(idx);
    +0271     end
    +0272 end
    +0273 value = node;
    +0274 end
    +0275 
    +0276 function data = setKey(data, path, value, filename, lineNo)
    +0277 name = path{1}{1}; idx = path{1}{2};
    +0278 if numel(path) == 1
    +0279     % [] only fills a field that another element of a table array has;
    +0280     % TOML itself has no empty value.
    +0281     if isfield(data, name) && ~isequal(data.(name), [])
    +0282         tomlError(filename, lineNo, sprintf('key "%s" is defined twice', name));
    +0283     end
    +0284     data.(name) = value;
    +0285     return
    +0286 end
    +0287 if ~isfield(data, name)
    +0288     data.(name) = struct();
    +0289 elseif ~isstruct(data.(name))
    +0290     tomlError(filename, lineNo, sprintf('"%s" is already a value, not a table', name));
    +0291 end
    +0292 child = data.(name);
    +0293 if idx == 0
    +0294     data.(name) = setKey(child, path(2:end), value, filename, lineNo);
    +0295 else
    +0296     element = setKey(child(idx), path(2:end), value, filename, lineNo);
    +0297     data.(name) = assignElement(child, idx, element);
    +0298 end
    +0299 end
    +0300 
    +0301 function s = assignElement(s, idx, element)
    +0302 % Assigns element to s(idx), adding fields so the struct array stays
    +0303 % consistent.
    +0304 if idx > numel(s) || isempty(fieldnames(s))
    +0305     if numel(s) == 1 && isempty(fieldnames(s)) && idx == 1
    +0306         s = element;
    +0307         return
    +0308     end
    +0309 end
    +0310 fs = fieldnames(element);
    +0311 for f = 1:numel(fs)
    +0312     if ~isfield(s, fs{f})
    +0313         [s.(fs{f})] = deal([]);
    +0314     end
    +0315 end
    +0316 fs = fieldnames(s);
    +0317 for f = 1:numel(fs)
    +0318     if ~isfield(element, fs{f})
    +0319         element.(fs{f}) = [];
    +0320     end
    +0321 end
    +0322 element = orderfields(element, s(1));
    +0323 s(idx) = element;
    +0324 end
    +0325 
    +0326 function value = parseValue(text, filename, lineNo)
    +0327 text = strtrim(text);
    +0328 if isempty(text)
    +0329     tomlError(filename, lineNo, 'missing value');
    +0330 end
    +0331 switch text(1)
    +0332     case '"'
    +0333         [value, rest] = parseBasicString(text, filename, lineNo);
    +0334     case ''''
    +0335         close = find(text(2:end) == '''', 1) + 1;
    +0336         if isempty(close)
    +0337             tomlError(filename, lineNo, 'string is not closed');
    +0338         end
    +0339         value = text(2:close-1);
    +0340         rest = text(close+1:end);
    +0341     case '['
    +0342         [value, rest] = parseArray(text, filename, lineNo);
    +0343     case '{'
    +0344         tomlError(filename, lineNo, 'inline tables are not supported; use a [table] instead');
    +0345     otherwise
    +0346         [value, rest] = parseScalar(text, filename, lineNo);
    +0347 end
    +0348 if ~isempty(strtrim(rest))
    +0349     tomlError(filename, lineNo, sprintf('unexpected text after the value: %s', strtrim(rest)));
    +0350 end
    +0351 end
    +0352 
    +0353 function [value, rest] = parseBasicString(text, filename, lineNo)
    +0354 value = '';
    +0355 k = 2;
    +0356 while k <= numel(text)
    +0357     c = text(k);
    +0358     if c == '"'
    +0359         rest = text(k+1:end);
    +0360         return
    +0361     elseif c == '\'
    +0362         if k == numel(text)
    +0363             break
    +0364         end
    +0365         e = text(k+1);
    +0366         switch e
    +0367             case 'n', value(end+1) = newline;
    +0368             case 't', value(end+1) = sprintf('\t');
    +0369             case '"', value(end+1) = '"';
    +0370             case '\', value(end+1) = '\';
    +0371             case 'u'
    +0372                 value(end+1) = char(hex2dec(text(k+2:k+5)));
    +0373                 k = k + 4;
    +0374             otherwise
    +0375                 tomlError(filename, lineNo, sprintf('escape \\%s is not supported', e));
    +0376         end
    +0377         k = k + 2;
    +0378         continue
    +0379     else
    +0380         value(end+1) = c; %#ok<AGROW>
    +0381     end
    +0382     k = k + 1;
    +0383 end
    +0384 tomlError(filename, lineNo, 'string is not closed');
    +0385 end
    +0386 
    +0387 function [value, rest] = parseArray(text, filename, lineNo)
    +0388 % Parses [a, b, ...]; returns a cell for strings, a vector otherwise.
    +0389 items = {};
    +0390 k = 2;
    +0391 while true
    +0392     while k <= numel(text) && (isspace(text(k)) || text(k) == ',')
    +0393         k = k + 1;
    +0394     end
    +0395     if k > numel(text)
    +0396         tomlError(filename, lineNo, 'array is not closed');
    +0397     end
    +0398     if text(k) == ']'
    +0399         rest = text(k+1:end);
    +0400         break
    +0401     end
    +0402     if text(k) == '['
    +0403         tomlError(filename, lineNo, 'nested arrays are not supported');
    +0404     end
    +0405     % Find the end of this element.
    +0406     if text(k) == '"'
    +0407         [item, after] = parseBasicString(text(k:end), filename, lineNo);
    +0408         k = numel(text) - numel(after) + 1;
    +0409     elseif text(k) == ''''
    +0410         close = find(text(k+1:end) == '''', 1) + k;
    +0411         if isempty(close)
    +0412             tomlError(filename, lineNo, 'string is not closed');
    +0413         end
    +0414         item = text(k+1:close-1);
    +0415         k = close + 1;
    +0416     else
    +0417         stop = k;
    +0418         while stop <= numel(text) && text(stop) ~= ',' && text(stop) ~= ']'
    +0419             stop = stop + 1;
    +0420         end
    +0421         [item, after] = parseScalar(strtrim(text(k:stop-1)), filename, lineNo);
    +0422         if ~isempty(strtrim(after))
    +0423             tomlError(filename, lineNo, 'unexpected text in array');
    +0424         end
    +0425         k = stop;
    +0426     end
    +0427     items{end+1} = item; %#ok<AGROW>
    +0428 end
    +0429 if isempty(items)
    +0430     value = {};
    +0431 elseif all(cellfun(@ischar, items))
    +0432     value = items;
    +0433 elseif all(cellfun(@(x) isnumeric(x) && isscalar(x), items))
    +0434     value = cell2mat(items);
    +0435 elseif all(cellfun(@islogical, items))
    +0436     value = cell2mat(items);
    +0437 else
    +0438     tomlError(filename, lineNo, 'arrays must hold values of one type');
    +0439 end
    +0440 end
    +0441 
    +0442 function [value, rest] = parseScalar(text, filename, lineNo)
    +0443 token = regexp(text, '^[^\s,\]]+', 'match', 'once');
    +0444 rest = text(numel(token)+1:end);
    +0445 switch token
    +0446     case 'true'
    +0447         value = true;
    +0448     case 'false'
    +0449         value = false;
    +0450     case {'inf', '+inf'}
    +0451         value = Inf;
    +0452     case '-inf'
    +0453         value = -Inf;
    +0454     case {'nan', '+nan', '-nan'}
    +0455         value = NaN;
    +0456     otherwise
    +0457         clean = strrep(token, '_', '');
    +0458         if ~isempty(regexp(clean, '^[+-]?(0|[1-9][0-9]*)$', 'once')) || ...
    +0459                 ~isempty(regexp(clean, '^[+-]?(0|[1-9][0-9]*)(\.[0-9]+)?([eE][+-]?[0-9]+)?$', 'once'))
    +0460             value = str2double(clean);
    +0461         elseif ~isempty(regexp(token, '^\d{4}-\d{2}-\d{2}', 'once'))
    +0462             tomlError(filename, lineNo, 'dates are not supported');
    +0463         else
    +0464             tomlError(filename, lineNo, sprintf('cannot read value "%s"; strings need quotes', token));
    +0465         end
    +0466 end
    +0467 end
    +0468 
    +0469 function tomlError(filename, lineNo, message)
    +0470 error('GECKO:readAdapterToml', '%s, line %d: %s', filename, lineNo, message);
    +0471 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/model_adapter/writeAdapterToml.html b/doc/src/model_adapter/writeAdapterToml.html new file mode 100644 index 00000000..47a6bf67 --- /dev/null +++ b/doc/src/model_adapter/writeAdapterToml.html @@ -0,0 +1,215 @@ + + + + Description of writeAdapterToml + + + + + + + + + +
    Home > src > model_adapter > writeAdapterToml.m
    + + + +

    writeAdapterToml +

    + +

    PURPOSE ^

    +
    writeAdapterToml Write a struct as a model adapter TOML file.
    + +

    SYNOPSIS ^

    +
    function writeAdapterToml(data, filename, header)
    + +

    DESCRIPTION ^

    +
     writeAdapterToml  Write a struct as a model adapter TOML file.
    +
    + Writes the subset of TOML that readAdapterToml reads: values first,
    + then each nested struct as a [table] and each struct array as an array
    + of tables ([[name]]).
    +
    + Parameters
    + ----------
    + data : struct
    +     values may be char or string scalars, numeric or logical scalars or
    +     vectors, cell arrays of char, structs and struct arrays.
    + filename : char
    +     path of the TOML file to write; an existing file is overwritten.
    + header : char or cell, optional
    +     comment lines written at the top of the file (without '#').
    +
    + Examples
    + --------
    +     writeAdapterToml(struct('sigma',0.5), 'model_adapter.toml', ...
    +         {'Adapter for ecYeastGEM'});
    +
    + See also
    + --------
    + readAdapterToml, convertAdapterToToml
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • convertAdapterToToml convertAdapterToToml Write the parameters of an adapter class to model_adapter.toml.
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function writeAdapterToml(data, filename, header)
    +0002 % writeAdapterToml  Write a struct as a model adapter TOML file.
    +0003 %
    +0004 % Writes the subset of TOML that readAdapterToml reads: values first,
    +0005 % then each nested struct as a [table] and each struct array as an array
    +0006 % of tables ([[name]]).
    +0007 %
    +0008 % Parameters
    +0009 % ----------
    +0010 % data : struct
    +0011 %     values may be char or string scalars, numeric or logical scalars or
    +0012 %     vectors, cell arrays of char, structs and struct arrays.
    +0013 % filename : char
    +0014 %     path of the TOML file to write; an existing file is overwritten.
    +0015 % header : char or cell, optional
    +0016 %     comment lines written at the top of the file (without '#').
    +0017 %
    +0018 % Examples
    +0019 % --------
    +0020 %     writeAdapterToml(struct('sigma',0.5), 'model_adapter.toml', ...
    +0021 %         {'Adapter for ecYeastGEM'});
    +0022 %
    +0023 % See also
    +0024 % --------
    +0025 % readAdapterToml, convertAdapterToToml
    +0026 
    +0027 if nargin < 3
    +0028     header = {};
    +0029 elseif ischar(header) || isstring(header)
    +0030     header = cellstr(header);
    +0031 end
    +0032 
    +0033 out = {};
    +0034 for k = 1:numel(header)
    +0035     out{end+1} = ['# ' header{k}]; %#ok<AGROW>
    +0036 end
    +0037 if ~isempty(header)
    +0038     out{end+1} = '';
    +0039 end
    +0040 out = writeTable(out, data, {});
    +0041 
    +0042 fid = fopen(filename, 'w');
    +0043 if fid < 0
    +0044     error('GECKO:writeAdapterToml', 'Cannot write %s', filename);
    +0045 end
    +0046 fprintf(fid, '%s\n', out{:});
    +0047 fclose(fid);
    +0048 end
    +0049 
    +0050 function out = writeTable(out, s, prefix)
    +0051 fields = fieldnames(s);
    +0052 tables = {};
    +0053 for k = 1:numel(fields)
    +0054     value = s.(fields{k});
    +0055     if isstruct(value)
    +0056         tables{end+1} = fields{k}; %#ok<AGROW>
    +0057     elseif isempty(value) && ~iscell(value) && ~ischar(value)
    +0058         continue % unset value; TOML has no null
    +0059     else
    +0060         out{end+1} = [fields{k} ' = ' formatValue(value, strjoin([prefix fields(k)], '.'))]; %#ok<AGROW>
    +0061     end
    +0062 end
    +0063 for k = 1:numel(tables)
    +0064     value = s.(tables{k});
    +0065     name = strjoin([prefix tables(k)], '.');
    +0066     if numel(value) == 1
    +0067         out{end+1} = ''; %#ok<AGROW>
    +0068         out{end+1} = ['[' name ']']; %#ok<AGROW>
    +0069         out = writeTable(out, value, [prefix tables(k)]);
    +0070     else
    +0071         for e = 1:numel(value)
    +0072             out{end+1} = ''; %#ok<AGROW>
    +0073             out{end+1} = ['[[' name ']]']; %#ok<AGROW>
    +0074             out = writeTable(out, value(e), [prefix tables(k)]);
    +0075         end
    +0076     end
    +0077 end
    +0078 end
    +0079 
    +0080 function text = formatValue(value, name)
    +0081 if isstring(value) && isscalar(value)
    +0082     value = char(value);
    +0083 end
    +0084 if ischar(value)
    +0085     text = quote(value);
    +0086 elseif iscell(value)
    +0087     if ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), value))
    +0088         error('GECKO:writeAdapterToml', '%s: only cell arrays of text can be written', name);
    +0089     end
    +0090     parts = cellfun(@(x) quote(char(x)), value, 'UniformOutput', false);
    +0091     text = ['[' strjoin(parts(:)', ', ') ']'];
    +0092 elseif islogical(value) || isnumeric(value)
    +0093     if isscalar(value)
    +0094         text = formatScalar(value);
    +0095     else
    +0096         parts = arrayfun(@formatScalar, value(:)', 'UniformOutput', false);
    +0097         text = ['[' strjoin(parts, ', ') ']'];
    +0098     end
    +0099 else
    +0100     error('GECKO:writeAdapterToml', '%s: values of class %s cannot be written', name, class(value));
    +0101 end
    +0102 end
    +0103 
    +0104 function text = formatScalar(x)
    +0105 if islogical(x)
    +0106     if x
    +0107         text = 'true';
    +0108     else
    +0109         text = 'false';
    +0110     end
    +0111 elseif isinf(x)
    +0112     if x > 0
    +0113         text = 'inf';
    +0114     else
    +0115         text = '-inf';
    +0116     end
    +0117 elseif isnan(x)
    +0118     text = 'nan';
    +0119 elseif x == round(x) && abs(x) < 1e15
    +0120     text = sprintf('%d', x);
    +0121 else
    +0122     text = sprintf('%.17g', x);
    +0123     % Use the shortest form that reads back to the same double.
    +0124     for p = 1:17
    +0125         candidate = sprintf('%.*g', p, x);
    +0126         if str2double(candidate) == x
    +0127             text = candidate;
    +0128             break
    +0129         end
    +0130     end
    +0131     if isempty(regexp(text, '[.eE]', 'once'))
    +0132         text = [text '.0'];
    +0133     end
    +0134 end
    +0135 end
    +0136 
    +0137 function text = quote(s)
    +0138 s = strrep(s, '\', '\\');
    +0139 s = strrep(s, '"', '\"');
    +0140 s = strrep(s, sprintf('\t'), '\t');
    +0141 s = strrep(s, newline, '\n');
    +0142 text = ['"' s '"'];
    +0143 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/utilities/buildGECKOdoc.html b/doc/src/utilities/buildGECKOdoc.html new file mode 100644 index 00000000..c2a67786 --- /dev/null +++ b/doc/src/utilities/buildGECKOdoc.html @@ -0,0 +1,94 @@ + + + + Description of buildGECKOdoc + + + + + + + + + +
    Home > src > utilities > buildGECKOdoc.m
    + + + +

    buildGECKOdoc +

    + +

    PURPOSE ^

    +
    buildGECKOdoc Update HTML documentation for all GECKO MATLAB functions.
    + +

    SYNOPSIS ^

    +
    function buildGECKOdoc()
    + +

    DESCRIPTION ^

    +
     buildGECKOdoc  Update HTML documentation for all GECKO MATLAB functions.
    +
    + Updates HTML documentation files for all GECKO MATLAB functions. Uses
    + the m2html functions that are provided with RAVEN.
    +
    + Examples
    + --------
    +     buildGECKOdoc();
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • findGECKOroot findGECKOroot Find the root of the GECKO directory.
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function buildGECKOdoc()
    +0002 % buildGECKOdoc  Update HTML documentation for all GECKO MATLAB functions.
    +0003 %
    +0004 % Updates HTML documentation files for all GECKO MATLAB functions. Uses
    +0005 % the m2html functions that are provided with RAVEN.
    +0006 %
    +0007 % Examples
    +0008 % --------
    +0009 %     buildGECKOdoc();
    +0010 
    +0011 %Make sure that RAVEN-provided m2html is used
    +0012 ravenDir=findRAVENroot();
    +0013 path(fullfile(ravenDir,'software','m2html'),path);
    +0014 
    +0015 %Get the GECKO path
    +0016 geckoDir=findGECKOroot();
    +0017 
    +0018 %Remove old doc directory
    +0019 rmdir(fullfile(geckoDir,'doc'),'s');
    +0020 
    +0021 %Get a non-redundant list of GECKO subdirectories containing MATLAB
    +0022 %functions. Absolute paths are not compatible with M2HTML, so convert them
    +0023 %to the relative paths instead.
    +0024 geckoDirs=dir(fullfile(geckoDir,'src','**/*.m'));
    +0025 geckoDirs=unique({geckoDirs.folder})';
    +0026 
    +0027 %Make relative path
    +0028 relStart = numel(geckoDir)+2;
    +0029 for i=1:numel(geckoDirs)
    +0030     geckoDirs{i,1} = geckoDirs{i,1}(relStart:end);
    +0031 end
    +0032 
    +0033 %Save the current working directory and go to RAVEN root directory
    +0034 originalDir=pwd;
    +0035 cd(geckoDir);
    +0036 %Generate HTML documentation files for RAVEN MATLAB functions
    +0037 m2html('mFiles',geckoDirs,'htmldir','doc');
    +0038 %Go back to the original working directory
    +0039 cd(originalDir);
    +0040 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/utilities/createGECKOproject.html b/doc/src/utilities/createGECKOproject.html new file mode 100644 index 00000000..e2263cf9 --- /dev/null +++ b/doc/src/utilities/createGECKOproject.html @@ -0,0 +1,157 @@ + + + + Description of createGECKOproject + + + + + + + + + +
    Home > src > utilities > createGECKOproject.m
    + + + +

    createGECKOproject +

    + +

    PURPOSE ^

    +
    createGECKOproject Create a basic project structure for GECKO.
    + +

    SYNOPSIS ^

    +
    function createGECKOproject(varargin)
    + +

    DESCRIPTION ^

    +
     createGECKOproject  Create a basic project structure for GECKO.
    +
    + Creates a basic project structure for GECKO. If a project with the same
    + name exists, the project will not be created.
    +
    + Name-Value Arguments
    + --------------------
    + name : char
    +     a name for the folder structure used in GECKO. Also creates a basic
    +     model adapter, which must be manually adjusted. If not defined, a
    +     dialog box will appear.
    + path : char
    +     a path where to create the folder. If not defined, a dialog box will
    +     appear.
    + adapterFormat : char
    +     'toml' (default) writes model_adapter.toml, which GECKO and geckopy
    +     both read (see TomlAdapter); 'class' writes an adapter class
    +     <name>Adapter.m instead.
    +
    + Examples
    + --------
    +     % optional arguments may be given positionally or as name-value pairs:
    +     createGECKOproject(name, path);
    +     createGECKOproject('name', name);
    +     createGECKOproject('name', name, 'adapterFormat', 'class');
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • findGECKOroot findGECKOroot Find the root of the GECKO directory.
    • parseGECKOargs parseGECKOargs Resolve optional arguments passed positionally or by name.
    +This function is called by: +
      +
    + + + + +

    SOURCE CODE ^

    +
    0001 function createGECKOproject(varargin)
    +0002 % createGECKOproject  Create a basic project structure for GECKO.
    +0003 %
    +0004 % Creates a basic project structure for GECKO. If a project with the same
    +0005 % name exists, the project will not be created.
    +0006 %
    +0007 % Name-Value Arguments
    +0008 % --------------------
    +0009 % name : char
    +0010 %     a name for the folder structure used in GECKO. Also creates a basic
    +0011 %     model adapter, which must be manually adjusted. If not defined, a
    +0012 %     dialog box will appear.
    +0013 % path : char
    +0014 %     a path where to create the folder. If not defined, a dialog box will
    +0015 %     appear.
    +0016 % adapterFormat : char
    +0017 %     'toml' (default) writes model_adapter.toml, which GECKO and geckopy
    +0018 %     both read (see TomlAdapter); 'class' writes an adapter class
    +0019 %     <name>Adapter.m instead.
    +0020 %
    +0021 % Examples
    +0022 % --------
    +0023 %     % optional arguments may be given positionally or as name-value pairs:
    +0024 %     createGECKOproject(name, path);
    +0025 %     createGECKOproject('name', name);
    +0026 %     createGECKOproject('name', name, 'adapterFormat', 'class');
    +0027 
    +0028 p = parseGECKOargs(varargin, { ...
    +0029     'name', []; ...
    +0030     'path', []; ...
    +0031     'adapterFormat', 'toml'});
    +0032 name = p.name;
    +0033 path = p.path;
    +0034 adapterFormat = validatestring(p.adapterFormat, {'toml','class'});
    +0035 
    +0036 if isempty(name)
    +0037     prompt = {'Please provide a project name (e.g. ecYeastGEM)'};
    +0038     dlgtitle = 'Project name';
    +0039     dims = [1 100];
    +0040     definput = {'ecModelGEM'};
    +0041     opts.Interpreter = 'tex';
    +0042     name = inputdlg(prompt,dlgtitle,dims,definput,opts);
    +0043     name = char(name);
    +0044 end
    +0045 
    +0046 if isempty(path)
    +0047     path = uigetdir('Project Folder path');
    +0048 end
    +0049 
    +0050 fullPath = fullfile(path, name);
    +0051 % Validate if the project does not exits
    +0052 if ~exist(fullPath, 'dir')
    +0053     % Create the subfolder
    +0054     dir = {'code', 'data', 'models', 'output'};
    +0055     for i = 1:length(dir)
    +0056         status = mkdir(fullPath, dir{i});
    +0057         fid = fopen(fullfile(fullPath, dir{i}, '.keep'), 'w');
    +0058         fclose(fid);
    +0059     end
    +0060 
    +0061     % Read the template adapter
    +0062     if strcmp(adapterFormat, 'toml')
    +0063         template = 'adapterTemplate.toml';
    +0064         filename = fullfile(path, name, 'model_adapter.toml');
    +0065     else
    +0066         template = 'adapterTemplate.m';
    +0067         filename = fullfile(path, name, [name 'Adapter.m']);
    +0068     end
    +0069     fid = fopen(fullfile(findGECKOroot, 'src', 'model_adapter', template));
    +0070     f = fread(fid, '*char')';
    +0071     fclose(fid);
    +0072 
    +0073     % Replace key values
    +0074     f = strrep(f, 'KEY_CLASSNAME', [name 'Adapter']);
    +0075     f = strrep(f, 'KEY_PATH', path);
    +0076     f = strrep(f, 'KEY_NAME', name);
    +0077 
    +0078     % Save the adapter
    +0079     fid = fopen(filename, 'w');
    +0080     fwrite(fid, f);
    +0081     fclose(fid);
    +0082 else
    +0083     printOrange('WARNING: A project with the same name exits at the same location. The project was not created.\n');
    +0084 end
    +0085 cd(fullPath)
    +0086 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/utilities/findGECKOroot.html b/doc/src/utilities/findGECKOroot.html new file mode 100644 index 00000000..8f91f961 --- /dev/null +++ b/doc/src/utilities/findGECKOroot.html @@ -0,0 +1,92 @@ + + + + Description of findGECKOroot + + + + + + + + + +
    Home > src > utilities > findGECKOroot.m
    + + + +

    findGECKOroot +

    + +

    PURPOSE ^

    +
    findGECKOroot Find the root of the GECKO directory.
    + +

    SYNOPSIS ^

    +
    function [geckoPath, prevDir] = findGECKOroot()
    + +

    DESCRIPTION ^

    +
     findGECKOroot  Find the root of the GECKO directory.
    +
    + Finds the root of the GECKO directory, by searching for the path to
    + GECKOInstaller.m. Can also record the current directory, in case a function
    + will use the geckoPath to navigate to a precise folder, and it should
    + return to the previous directory afterwards.
    +
    + Returns
    + -------
    + geckoPath : char
    +     path to the root of the GECKO directory.
    + prevDir : char
    +     the current directory at the time of the call, recorded so that a
    +     function can return to it afterwards.
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: +
      +
    • buildGECKOdoc buildGECKOdoc Update HTML documentation for all GECKO MATLAB functions.
    • createGECKOproject createGECKOproject Create a basic project structure for GECKO.
    • upgradeGECKOproject upgradeGECKOproject Bring a GECKO 3 project to the GECKO 4 layout.
    + + + + +

    SOURCE CODE ^

    +
    0001 function [geckoPath, prevDir] = findGECKOroot()
    +0002 % findGECKOroot  Find the root of the GECKO directory.
    +0003 %
    +0004 % Finds the root of the GECKO directory, by searching for the path to
    +0005 % GECKOInstaller.m. Can also record the current directory, in case a function
    +0006 % will use the geckoPath to navigate to a precise folder, and it should
    +0007 % return to the previous directory afterwards.
    +0008 %
    +0009 % Returns
    +0010 % -------
    +0011 % geckoPath : char
    +0012 %     path to the root of the GECKO directory.
    +0013 % prevDir : char
    +0014 %     the current directory at the time of the call, recorded so that a
    +0015 %     function can return to it afterwards.
    +0016 
    +0017 ST=dbstack('-completenames');
    +0018 prevDir = pwd();
    +0019 geckoPath = ST(strcmp({ST.name},'findGECKOroot')).file;
    +0020 rootFound = 0;
    +0021 while rootFound == 0
    +0022     isRoot = exist(fullfile(geckoPath,'GECKOInstaller.m'),'file');
    +0023     if isRoot == 2
    +0024         rootFound = 1;
    +0025     else
    +0026         ravenPathOld = geckoPath;
    +0027         geckoPath = fileparts(geckoPath);
    +0028         if strcmp(ravenPathOld,geckoPath)
    +0029             error('Cannot find the GECKO root directory. Make sure you have not removed the GECKOInstaller.m file from your GECKO installation.')
    +0030         end
    +0031     end
    +0032 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/utilities/index.html b/doc/src/utilities/index.html new file mode 100644 index 00000000..e028aa29 --- /dev/null +++ b/doc/src/utilities/index.html @@ -0,0 +1,29 @@ + + + + Index for Directory src/utilities + + + + + + + + + + +
    < Master indexIndex for src/utilities >
    + +

    Index for src/utilities

    + +

    Matlab files in this directory:

    + +
     buildGECKOdocbuildGECKOdoc Update HTML documentation for all GECKO MATLAB functions.
     createGECKOprojectcreateGECKOproject Create a basic project structure for GECKO.
     findGECKOrootfindGECKOroot Find the root of the GECKO directory.
     parseGECKOargsparseGECKOargs Resolve optional arguments passed positionally or by name.
     upgradeGECKOprojectupgradeGECKOproject Bring a GECKO 3 project to the GECKO 4 layout.
    + + + + +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/utilities/parseGECKOargs.html b/doc/src/utilities/parseGECKOargs.html new file mode 100644 index 00000000..53994f4d --- /dev/null +++ b/doc/src/utilities/parseGECKOargs.html @@ -0,0 +1,195 @@ + + + + Description of parseGECKOargs + + + + + + + + + +
    Home > src > utilities > parseGECKOargs.m
    + + + +

    parseGECKOargs +

    + +

    PURPOSE ^

    +
    parseGECKOargs Resolve optional arguments passed positionally or by name.
    + +

    SYNOPSIS ^

    +
    function args = parseGECKOargs(rawArgs, spec)
    + +

    DESCRIPTION ^

    +
     parseGECKOargs  Resolve optional arguments passed positionally or by name.
    +
    + Helper that lets a GECKO function accept its optional arguments either in
    + the traditional positional order or as name-value pairs, without losing
    + backward compatibility. The required leading arguments stay explicit in the
    + function signature; the optional tail is collected into varargin and passed
    + here together with a specification of the optional parameters.
    +
    + Parameters
    + ----------
    + rawArgs : cell
    +     the function's varargin, i.e. whatever was supplied after the required
    +     positional arguments.
    + spec : cell
    +     an N-by-2 or N-by-3 cell array describing the optional parameters, one
    +     per row:
    +
    +     - column 1 : parameter name (char).
    +     - column 2 : default value, used when the parameter is not supplied.
    +     - column 3 : optional validator, a function handle that is called with
    +       the resolved value and should error on an invalid value. Use [] for
    +       no validation.
    +
    + Returns
    + -------
    + args : struct
    +     a struct with one field per parameter name, holding the resolved value.
    +
    + Notes
    + -----
    + The calling convention is detected from rawArgs: it is treated as name-
    + value pairs only when it has an even number of elements AND every element
    + in a name position is a string matching one of the declared parameter
    + names. Otherwise it is treated as positional and assigned in the order of
    + the spec. A call therefore uses either the positional or the name-value
    + form for the optional tail, not a mix of the two. When an optional tail
    + value could itself be a string equal to a parameter name, use the explicit
    + name-value form to remove the ambiguity.
    +
    + Examples
    + --------
    +     % inside makeEcModel(model, varargin):
    +     p = parseGECKOargs(varargin, { ...
    +         'geckoLight',   false; ...
    +         'modelAdapter', []});
    +     geckoLight   = p.geckoLight;
    +     modelAdapter = p.modelAdapter;
    +
    +     % the caller may then use either form:
    +     makeEcModel(model, true, adapter)                  % positional
    +     makeEcModel(model, 'geckoLight', true)             % named
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    +This function is called by: + + + + + +

    SOURCE CODE ^

    +
    0001 function args = parseGECKOargs(rawArgs, spec)
    +0002 % parseGECKOargs  Resolve optional arguments passed positionally or by name.
    +0003 %
    +0004 % Helper that lets a GECKO function accept its optional arguments either in
    +0005 % the traditional positional order or as name-value pairs, without losing
    +0006 % backward compatibility. The required leading arguments stay explicit in the
    +0007 % function signature; the optional tail is collected into varargin and passed
    +0008 % here together with a specification of the optional parameters.
    +0009 %
    +0010 % Parameters
    +0011 % ----------
    +0012 % rawArgs : cell
    +0013 %     the function's varargin, i.e. whatever was supplied after the required
    +0014 %     positional arguments.
    +0015 % spec : cell
    +0016 %     an N-by-2 or N-by-3 cell array describing the optional parameters, one
    +0017 %     per row:
    +0018 %
    +0019 %     - column 1 : parameter name (char).
    +0020 %     - column 2 : default value, used when the parameter is not supplied.
    +0021 %     - column 3 : optional validator, a function handle that is called with
    +0022 %       the resolved value and should error on an invalid value. Use [] for
    +0023 %       no validation.
    +0024 %
    +0025 % Returns
    +0026 % -------
    +0027 % args : struct
    +0028 %     a struct with one field per parameter name, holding the resolved value.
    +0029 %
    +0030 % Notes
    +0031 % -----
    +0032 % The calling convention is detected from rawArgs: it is treated as name-
    +0033 % value pairs only when it has an even number of elements AND every element
    +0034 % in a name position is a string matching one of the declared parameter
    +0035 % names. Otherwise it is treated as positional and assigned in the order of
    +0036 % the spec. A call therefore uses either the positional or the name-value
    +0037 % form for the optional tail, not a mix of the two. When an optional tail
    +0038 % value could itself be a string equal to a parameter name, use the explicit
    +0039 % name-value form to remove the ambiguity.
    +0040 %
    +0041 % Examples
    +0042 % --------
    +0043 %     % inside makeEcModel(model, varargin):
    +0044 %     p = parseGECKOargs(varargin, { ...
    +0045 %         'geckoLight',   false; ...
    +0046 %         'modelAdapter', []});
    +0047 %     geckoLight   = p.geckoLight;
    +0048 %     modelAdapter = p.modelAdapter;
    +0049 %
    +0050 %     % the caller may then use either form:
    +0051 %     makeEcModel(model, true, adapter)                  % positional
    +0052 %     makeEcModel(model, 'geckoLight', true)             % named
    +0053 
    +0054 if nargin < 2 || isempty(spec)
    +0055     error('parseGECKOargs:noSpec', 'A parameter specification is required.');
    +0056 end
    +0057 
    +0058 names = spec(:, 1);
    +0059 defaults = spec(:, 2);
    +0060 hasValidators = size(spec, 2) >= 3;
    +0061 
    +0062 % Seed every parameter with its default.
    +0063 args = struct();
    +0064 for i = 1:numel(names)
    +0065     args.(names{i}) = defaults{i};
    +0066 end
    +0067 
    +0068 if ~isempty(rawArgs)
    +0069     isNameValue = mod(numel(rawArgs), 2) == 0 && ...
    +0070         all(cellfun(@(x) (ischar(x) || isstring(x)) && isscalar(string(x)) && ...
    +0071         any(strcmpi(x, names)), rawArgs(1:2:end)));
    +0072 
    +0073     if isNameValue
    +0074         for k = 1:2:numel(rawArgs)
    +0075             args.(names{strcmpi(rawArgs{k}, names)}) = rawArgs{k + 1};
    +0076         end
    +0077     else
    +0078         if numel(rawArgs) > numel(names)
    +0079             error('parseGECKOargs:tooManyArgs', ...
    +0080                 'Too many positional arguments: expected at most %d, got %d.', ...
    +0081                 numel(names), numel(rawArgs));
    +0082         end
    +0083         for k = 1:numel(rawArgs)
    +0084             args.(names{k}) = rawArgs{k};
    +0085         end
    +0086     end
    +0087 end
    +0088 
    +0089 % Apply optional validators.
    +0090 if hasValidators
    +0091     for i = 1:numel(names)
    +0092         validator = spec{i, 3};
    +0093         if ~isempty(validator)
    +0094             validator(args.(names{i}));
    +0095         end
    +0096     end
    +0097 end
    +0098 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/doc/src/utilities/upgradeGECKOproject.html b/doc/src/utilities/upgradeGECKOproject.html new file mode 100644 index 00000000..3c113522 --- /dev/null +++ b/doc/src/utilities/upgradeGECKOproject.html @@ -0,0 +1,409 @@ + + + + Description of upgradeGECKOproject + + + + + + + + + +
    Home > src > utilities > upgradeGECKOproject.m
    + + + +

    upgradeGECKOproject +

    + +

    PURPOSE ^

    +
    upgradeGECKOproject Bring a GECKO 3 project to the GECKO 4 layout.
    + +

    SYNOPSIS ^

    +
    function report = upgradeGECKOproject(projectPath, varargin)
    + +

    DESCRIPTION ^

    +
     upgradeGECKOproject  Bring a GECKO 3 project to the GECKO 4 layout.
    +
    + Lists, and with 'dryRun', false carries out, the steps that bring a
    + project made with GECKO 3 (or an earlier GECKO 4) to the current layout:
    +
    + 1. adapter: an adapter class without model_adapter.toml gets one
    +    (convertAdapterToToml). Methods the class overrides are listed: they
    +    need carrying over by hand. The class itself stays.
    + 2. custom kcats: data/customKcats.tsv becomes data/kcats/custom.tsv
    +    (convertCustomKcats).
    + 3. stored predictions: data/DLKcat.tsv and stored OpenKineticsPredictor
    +    results become kcat source files (kcatsFromDLKcat, kcatsFromOKP with
    +    'useStored'), without running anything.
    + Steps 2 and 3 need the full ecModel the custom kcats and predictions are
    + for ('ecModel'); without it they are listed and skipped.
    + 4. saved ecModels: models/*.yml ecModels made with GECKO 3 get their
    +    protein usage and pool reactions turned forward (upgradeEcModel).
    + 5. project_format = 4 is written to model_adapter.toml.
    + 6. scripts: lines of the project's .m files that call renamed or replaced
    +    functions are listed, not changed.
    +
    + A file that is replaced or converted is first moved to
    + legacy/<yyyy-mm-dd>/ in the project, keeping its place in the folder
    + tree. Steps that are already done are left out, so the function can run
    + again. geckopy has the same as `geckopy upgrade` (upgrade_project).
    +
    + Parameters
    + ----------
    + projectPath : char
    +     the project folder.
    +
    + Name-Value Arguments
    + --------------------
    + dryRun : logical
    +     only list the steps (default true).
    + ecModel : struct
    +     the ecModel the stored predictions were made for (step 3).
    +
    + Returns
    + -------
    + report : table
    +     one row per step: step, status ('to do', 'done', 'skipped', 'failed',
    +     'by hand') and note; script lines are listed one per row.
    +
    + Examples
    + --------
    +     upgradeGECKOproject(projectPath)                    % see what it would do
    +     upgradeGECKOproject(projectPath, 'dryRun', false, 'ecModel', ecModel)
    +
    + See also
    + --------
    + convertAdapterToToml, convertCustomKcats, upgradeEcModel, createGECKOproject
    + + +

    CROSS-REFERENCE INFORMATION ^

    +This function calls: +
      +
    • findGECKOroot findGECKOroot Find the root of the GECKO directory.
    • parseGECKOargs parseGECKOargs Resolve optional arguments passed positionally or by name.
    +This function is called by: +
      +
    + + +

    SUBFUNCTIONS ^

    + + +

    SOURCE CODE ^

    +
    0001 function report = upgradeGECKOproject(projectPath, varargin)
    +0002 % upgradeGECKOproject  Bring a GECKO 3 project to the GECKO 4 layout.
    +0003 %
    +0004 % Lists, and with 'dryRun', false carries out, the steps that bring a
    +0005 % project made with GECKO 3 (or an earlier GECKO 4) to the current layout:
    +0006 %
    +0007 % 1. adapter: an adapter class without model_adapter.toml gets one
    +0008 %    (convertAdapterToToml). Methods the class overrides are listed: they
    +0009 %    need carrying over by hand. The class itself stays.
    +0010 % 2. custom kcats: data/customKcats.tsv becomes data/kcats/custom.tsv
    +0011 %    (convertCustomKcats).
    +0012 % 3. stored predictions: data/DLKcat.tsv and stored OpenKineticsPredictor
    +0013 %    results become kcat source files (kcatsFromDLKcat, kcatsFromOKP with
    +0014 %    'useStored'), without running anything.
    +0015 % Steps 2 and 3 need the full ecModel the custom kcats and predictions are
    +0016 % for ('ecModel'); without it they are listed and skipped.
    +0017 % 4. saved ecModels: models/*.yml ecModels made with GECKO 3 get their
    +0018 %    protein usage and pool reactions turned forward (upgradeEcModel).
    +0019 % 5. project_format = 4 is written to model_adapter.toml.
    +0020 % 6. scripts: lines of the project's .m files that call renamed or replaced
    +0021 %    functions are listed, not changed.
    +0022 %
    +0023 % A file that is replaced or converted is first moved to
    +0024 % legacy/<yyyy-mm-dd>/ in the project, keeping its place in the folder
    +0025 % tree. Steps that are already done are left out, so the function can run
    +0026 % again. geckopy has the same as `geckopy upgrade` (upgrade_project).
    +0027 %
    +0028 % Parameters
    +0029 % ----------
    +0030 % projectPath : char
    +0031 %     the project folder.
    +0032 %
    +0033 % Name-Value Arguments
    +0034 % --------------------
    +0035 % dryRun : logical
    +0036 %     only list the steps (default true).
    +0037 % ecModel : struct
    +0038 %     the ecModel the stored predictions were made for (step 3).
    +0039 %
    +0040 % Returns
    +0041 % -------
    +0042 % report : table
    +0043 %     one row per step: step, status ('to do', 'done', 'skipped', 'failed',
    +0044 %     'by hand') and note; script lines are listed one per row.
    +0045 %
    +0046 % Examples
    +0047 % --------
    +0048 %     upgradeGECKOproject(projectPath)                    % see what it would do
    +0049 %     upgradeGECKOproject(projectPath, 'dryRun', false, 'ecModel', ecModel)
    +0050 %
    +0051 % See also
    +0052 % --------
    +0053 % convertAdapterToToml, convertCustomKcats, upgradeEcModel, createGECKOproject
    +0054 
    +0055 checkOptions(varargin, {'dryRun','ecModel'}, 'upgradeGECKOproject');
    +0056 p = parseGECKOargs(varargin, {'dryRun', true; 'ecModel', []});
    +0057 projectPath = char(projectPath);
    +0058 if ~isfolder(projectPath)
    +0059     error('upgradeGECKOproject:path', 'No folder %s.', projectPath)
    +0060 end
    +0061 apply = ~p.dryRun;
    +0062 legacy = fullfile(projectPath, 'legacy', char(datetime('now', 'Format', 'yyyy-MM-dd')));
    +0063 toml = fullfile(projectPath, 'model_adapter.toml');
    +0064 rows = cell(0, 3);
    +0065     function add(step, status, note)
    +0066         rows(end+1, :) = {step, status, note};
    +0067     end
    +0068     function keepOriginal(file)
    +0069         % Move a file to legacy/<date>/, at its place in the folder tree.
    +0070         rel = file(numel(projectPath)+2:end);
    +0071         target = fullfile(legacy, rel);
    +0072         if ~isfolder(fileparts(target))
    +0073             mkdir(fileparts(target));
    +0074         end
    +0075         movefile(file, target);
    +0076     end
    +0077 status = 'to do';
    +0078 if apply
    +0079     status = 'done';
    +0080 end
    +0081 
    +0082 % 1. Adapter class -> model_adapter.toml
    +0083 if ~isfile(toml)
    +0084     classFile = adapterClass(projectPath);
    +0085     if isempty(classFile)
    +0086         add('adapter', 'by hand', 'no model_adapter.toml and no adapter class; see createGECKOproject');
    +0087     else
    +0088         note = sprintf('%s -> model_adapter.toml', relative(classFile, projectPath));
    +0089         if apply
    +0090             r = convertAdapterToToml(classFile, toml);
    +0091             if ~isempty(r.methods)
    +0092                 add('adapter methods', 'by hand', ['carry over: ' strjoin(r.methods, ', ')]);
    +0093             end
    +0094         end
    +0095         add('adapter', status, note);
    +0096     end
    +0097 end
    +0098 
    +0099 % 2. customKcats.tsv -> data/kcats/custom.tsv
    +0100 custom = fullfile(projectPath, 'data', 'customKcats.tsv');
    +0101 customOut = fullfile(projectPath, 'data', 'kcats', 'custom.tsv');
    +0102 if isfile(custom) && ~isfile(customOut)
    +0103     note = 'data/customKcats.tsv -> data/kcats/custom.tsv';
    +0104     if isempty(p.ecModel)
    +0105         add('custom kcats', 'skipped', [note '; give the ecModel they are for (''ecModel'')']);
    +0106     else
    +0107         if apply
    +0108             [~, r] = convertCustomKcats(p.ecModel, 'customKcats', custom, 'outFile', customOut, ...
    +0109                 'modelAdapter', projectAdapter(projectPath));
    +0110             keepOriginal(custom);
    +0111             note = sprintf('%s (%d rows)', note, r.rows);
    +0112         end
    +0113         add('custom kcats', status, note);
    +0114     end
    +0115 end
    +0116 
    +0117 % 3. Stored predictions -> kcat source files
    +0118 stored = {};
    +0119 if isfile(fullfile(projectPath, 'data', 'DLKcat.tsv')) && ~isfile(fullfile(projectPath, 'data', 'kcats', 'dlkcat.tsv'))
    +0120     stored{end+1} = 'dlkcat';
    +0121 end
    +0122 okpFiles = dir(fullfile(projectPath, 'data', 'OKP_output*.csv'));
    +0123 for k = 1:numel(okpFiles)
    +0124     method = okpMethod(projectPath, okpFiles(k).name);
    +0125     if ~isempty(method)
    +0126         name = ['okp_' lower(regexprep(regexprep(method, '[^A-Za-z0-9]+', '_'), '^_+|_+$', ''))];
    +0127         if ~isfile(fullfile(projectPath, 'data', 'kcats', [name '.tsv']))
    +0128             stored{end+1} = method; %#ok<AGROW>
    +0129         end
    +0130     end
    +0131 end
    +0132 stored = unique(stored, 'stable');
    +0133 if ~isempty(stored)
    +0134     note = ['stored predictions -> data/kcats: ' strjoin(stored, ', ')];
    +0135     if isempty(p.ecModel)
    +0136         add('predictions', 'skipped', [note '; give the ecModel they were made for (''ecModel'')']);
    +0137     else
    +0138         if apply
    +0139             adapter = projectAdapter(projectPath);
    +0140             for k = 1:numel(stored)
    +0141                 try
    +0142                     if strcmp(stored{k}, 'dlkcat')
    +0143                         kcatsFromDLKcat(p.ecModel, 'modelAdapter', adapter);
    +0144                     else
    +0145                         kcatsFromOKP(p.ecModel, 'method', stored{k}, 'useStored', true, 'modelAdapter', adapter);
    +0146                     end
    +0147                     add('predictions', status, ['stored predictions -> data/kcats: ' stored{k}]);
    +0148                 catch err
    +0149                     add('predictions', 'failed', sprintf('%s: %s', stored{k}, err.message));
    +0150                 end
    +0151             end
    +0152         else
    +0153             add('predictions', status, note);
    +0154         end
    +0155     end
    +0156 end
    +0157 
    +0158 % 4. Saved ecModels: protein reactions turned forward
    +0159 models = dir(fullfile(projectPath, 'models', '*.yml'));
    +0160 for k = 1:numel(models)
    +0161     file = fullfile(models(k).folder, models(k).name);
    +0162     if ~contains(fileread(file), 'prot_pool')
    +0163         continue
    +0164     end
    +0165     try
    +0166         model = readYAMLmodel(file);
    +0167     catch err
    +0168         add('saved ecModel', 'failed', sprintf('%s: %s', relative(file, projectPath), err.message));
    +0169         continue
    +0170     end
    +0171     if isfield(model.annotation, 'gecko_format') && str2double(model.annotation.gecko_format) > 4
    +0172         add('saved ecModel', 'failed', sprintf('%s: ecModel format %s is newer than this GECKO', ...
    +0173             relative(file, projectPath), model.annotation.gecko_format));
    +0174         continue
    +0175     end
    +0176     [model, changed] = upgradeEcModel(model);
    +0177     if isempty(changed)
    +0178         continue
    +0179     end
    +0180     if apply
    +0181         model.annotation.generator = ['GECKO ' geckoVersion()];
    +0182         keepOriginal(file);
    +0183         writeYAMLmodel(model, file);
    +0184     end
    +0185     add('saved ecModel', status, sprintf('%s: %d protein reactions turned forward', ...
    +0186         relative(file, projectPath), numel(changed)));
    +0187 end
    +0188 
    +0189 % 5. project_format in model_adapter.toml
    +0190 adapterRow = strcmp(rows(:, 1), 'adapter') & ~strcmp(rows(:, 2), 'by hand');
    +0191 if isfile(toml) || any(adapterRow)
    +0192     if ~isfile(toml) || isempty(regexp(fileread(toml), '(?m)^\s*project_format\s*=', 'once'))
    +0193         if apply
    +0194             text = fileread(toml);
    +0195             fid = fopen(toml, 'w', 'n', 'UTF-8');
    +0196             fprintf(fid, 'project_format = 4\n%s', text);
    +0197             fclose(fid);
    +0198         end
    +0199         add('project format', status, 'project_format = 4 in model_adapter.toml');
    +0200     end
    +0201 end
    +0202 
    +0203 % 6. Scripts that call renamed or replaced functions
    +0204 renamed = { ...
    +0205     'enzymeUsage', 'getEnzymeUsage'; 'pfbaEnzymes', 'getPfbaEnzymes'; ...
    +0206     'selectKcatValue', 'assignKcatValues'; 'startGECKOproject', 'createGECKOproject'; ...
    +0207     'updateGECKOdoc', 'buildGECKOdoc'; 'copyECtoGEM', 'applyECcodes'; ...
    +0208     'addCarbonNum', 'fillCarbonNum'; 'updateprior', 'updatePrior'; ...
    +0209     'mergeDLKcatAndFuzzyKcats', 'mergeKcats'; ...
    +0210     'fuzzyKcatMatching', 'kcatsFromBrenda (or kcatsFromECTree), then assignKcats'; ...
    +0211     'readDLKcatOutput', 'kcatsFromDLKcat, then assignKcats'; ...
    +0212     'readOpenKineticsPredictorOutput', 'kcatsFromOKP, then assignKcats'; ...
    +0213     'writeOpenKineticsPredictorInput', 'kcatsFromOKP'; ...
    +0214     'applyCustomKcats', 'data/kcats/custom.tsv and assignKcats'};
    +0215 scripts = dir(fullfile(projectPath, '**', '*.m'));
    +0216 for k = 1:numel(scripts)
    +0217     file = fullfile(scripts(k).folder, scripts(k).name);
    +0218     if startsWith(file, fullfile(projectPath, 'legacy'))
    +0219         continue
    +0220     end
    +0221     lines = strsplit(fileread(file), {'\r\n', '\n'});
    +0222     for r = 1:size(renamed, 1)
    +0223         hit = find(~cellfun(@isempty, regexp(lines, ['(?<![\w.])' renamed{r, 1} '\s*\('], 'once')));
    +0224         for h = hit(:)'
    +0225             add('script', 'by hand', sprintf('%s:%d: %s -> %s', relative(file, projectPath), h, ...
    +0226                 renamed{r, 1}, renamed{r, 2}));
    +0227         end
    +0228     end
    +0229 end
    +0230 
    +0231 report = cell2table(rows, 'VariableNames', {'step', 'status', 'note'});
    +0232 if isempty(rows)
    +0233     fprintf('%s has the current GECKO 4 layout.\n', projectPath);
    +0234 else
    +0235     disp(report)
    +0236     if ~apply && any(strcmp(rows(:, 2), 'to do'))
    +0237         fprintf('Run upgradeGECKOproject(projectPath, ''dryRun'', false) to carry out the steps; originals go to %s.\n', legacy);
    +0238     end
    +0239 end
    +0240 end
    +0241 
    +0242 function adapter = projectAdapter(projectPath)
    +0243 % The project's adapter: from model_adapter.toml, or its adapter class.
    +0244 if isfile(fullfile(projectPath, 'model_adapter.toml'))
    +0245     adapter = TomlAdapter(projectPath);
    +0246 else
    +0247     adapter = ModelAdapterManager.getAdapter(adapterClass(projectPath));
    +0248     adapter.params.path = projectPath;
    +0249 end
    +0250 end
    +0251 
    +0252 function file = adapterClass(projectPath)
    +0253 % The adapter class in the project folder, or '' when there is none.
    +0254 file = '';
    +0255 candidates = dir(fullfile(projectPath, '*.m'));
    +0256 for k = 1:numel(candidates)
    +0257     f = fullfile(candidates(k).folder, candidates(k).name);
    +0258     if ~isempty(regexp(fileread(f), '(?m)^\s*classdef\s+\w+\s*<\s*ModelAdapter', 'once'))
    +0259         file = f;
    +0260         return
    +0261     end
    +0262 end
    +0263 end
    +0264 
    +0265 function method = okpMethod(projectPath, outName)
    +0266 % The OKP method of a stored result: from its own job file
    +0267 % (OKP_job_<tag>.txt), or from OKP_job.txt for the shared OKP_output.csv.
    +0268 method = '';
    +0269 if strcmp(outName, 'OKP_output.csv')
    +0270     jobFile = fullfile(projectPath, 'data', 'OKP_job.txt');
    +0271 else
    +0272     jobFile = fullfile(projectPath, 'data', ['OKP_job_' regexprep(outName, '^OKP_output_|\.csv$', '') '.txt']);
    +0273 end
    +0274 if ~isfile(jobFile)
    +0275     return
    +0276 end
    +0277 tok = regexp(fileread(jobFile), '(?m)^method:\s*(\S+)', 'tokens', 'once');
    +0278 if ~isempty(tok)
    +0279     method = tok{1};
    +0280 end
    +0281 end
    +0282 
    +0283 function r = relative(file, projectPath)
    +0284 r = file(numel(projectPath)+2:end);
    +0285 end
    +0286 
    +0287 function checkOptions(args, names, functionName)
    +0288 % Options are name-value pairs with known names, so a misspelled option is
    +0289 % an error instead of being taken as a positional argument.
    +0290 id = [functionName ':arguments'];
    +0291 given = args(1:2:end);
    +0292 if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given))
    +0293     error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', '))
    +0294 end
    +0295 unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names);
    +0296 if ~isempty(unknown)
    +0297     error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ...
    +0298         strjoin(names, ', '))
    +0299 end
    +0300 end
    +0301 
    +0302 function v = geckoVersion()
    +0303 file = fullfile(findGECKOroot, 'version.txt');
    +0304 if isfile(file)
    +0305     v = strtrim(fileread(file));
    +0306 else
    +0307     v = 'unknown';
    +0308 end
    +0309 end
    +
    Generated by m2html © 2005
    + + \ No newline at end of file diff --git a/img/gecko-logo-white.png b/img/gecko-logo-white.png new file mode 100644 index 00000000..b8653382 Binary files /dev/null and b/img/gecko-logo-white.png differ diff --git a/img/gecko-logo.png b/img/gecko-logo.png new file mode 100644 index 00000000..267e9cc5 Binary files /dev/null and b/img/gecko-logo.png differ diff --git a/src/change_model/addNewRxnsToEC.m b/src/change_model/addNewRxnsToEC.m index 7d7e99f5..9648356c 100644 --- a/src/change_model/addNewRxnsToEC.m +++ b/src/change_model/addNewRxnsToEC.m @@ -35,7 +35,7 @@ % - rxns : cell array with unique strings that identifies each reaction. % - rxnNames : cell array with the names of each reaction. % - equations : cell array with equation strings. Decimal coefficients are expressed as "1.2". Reversibility is indicated by "<=>" or "=>". -% - grRules : cell array with the gene-reaction relationship for each reaction. For example "(A and B) or (C)" means that the reaction could be catalyzed by a complex between A & B or by C on its own. All the genes have to be present in model.genes. Add genes with addGenesRaven before calling this function if needed (opt, default ''). +% - grRules : cell array with the gene-reaction relationship for each reaction. For example "(A and B) or (C)" means that the reaction could be catalyzed by a complex between A & B or by C on its own. A rule with brackets is split into its isozymes in disjunctive normal form, so "A and (B or C)" is the two isozymes "A and B" and "A and C". All the genes have to be present in model.genes. Add genes with addGenesRaven before calling this function if needed (opt, default ''). % % The newEnzymes structure has the following fields: % @@ -50,7 +50,9 @@ % Note that the reversibility defined in the equation will be used to % split to construct irreversible reactions (add _REV) and the rules % defined will be used to expand the model (add _EXP_n). -% 2. After adding the new reactions, setKcatForReactions or +% 2. When all the genes of the new reactions already have enzymes, no +% newEnzymes are needed. +% 3. After adding the new reactions, setKcatForReactions or % applyCustomKcats should be run to add the kcat to the reactions, and % subsequently applyKcatConstraints. % @@ -78,8 +80,9 @@ end params = modelAdapter.getParameters(); +enzAdded = {}; if isempty(newEnzymes) - newEnzymes = []; + newEnzymes = struct('enzymes', {{}}, 'genes', {{}}, 'mw', []); end % Validate if GECKO version 3 @@ -91,7 +94,7 @@ error('addNewRxnsToEC only works on non-light ecModels') else % Check if the new proteins are not already present in the model - if ~isempty(newEnzymes) + if ~isempty(newEnzymes.enzymes) [toRemove,~] = ismember(newEnzymes.enzymes, model.ec.enzymes); % Remove from the list those enzymes that already present @@ -136,11 +139,17 @@ % 3. Add new reactions + % The operators of a gene rule are case insensitive: write them in lower + % case, as the rest of the function and RAVEN's addRxns expect. Gene ids + % that contain the letters (Sand1, andA, ORF1) are left as they are. + newRxns.grRules = regexprep(convertCharArray(newRxns.grRules), ... + '(? 1); if ~isempty(toSplit) splitRxns = {}; splitRxnNames = {}; splitEquations = {}; splitGrRules = {}; for i=1:numel(toSplit) idx = toSplit(i); - newRules = split(newRxns.grRules(idx),'or'); - newRules = strtrim(erase(newRules, {'(' ')'})); + % One reaction per AND-clause of the gene rule in disjunctive normal form + newRules = cellfun(@(x) strjoin(x,' and '), isozymes{idx}, 'UniformOutput', false); for j=1:numel(newRules) splitRxns{end+1} = [newRxns.rxns{idx} '_EXP_' num2str(j)]; @@ -206,19 +216,21 @@ model = addRxns(model, newRxns, 3, '', true, true); % 4. Add protein usage reactions. - usageRxns.rxns = strcat('usage_',proteinMets.mets); - usageRxns.rxnNames = usageRxns.rxns; - usageRxns.mets = cell(numel(usageRxns.rxns),1); - usageRxns.stoichCoeffs = cell(numel(usageRxns.rxns),1); - for i=1:numel(usageRxns.mets) - usageRxns.mets{i} = {proteinMets.mets{i}, 'prot_pool'}; - usageRxns.stoichCoeffs{i} = [1,-1]; + if ~isempty(newEnzymes.enzymes) + usageRxns.rxns = strcat('usage_',proteinMets.mets); + usageRxns.rxnNames = usageRxns.rxns; + usageRxns.mets = cell(numel(usageRxns.rxns),1); + usageRxns.stoichCoeffs = cell(numel(usageRxns.rxns),1); + for i=1:numel(usageRxns.mets) + usageRxns.mets{i} = {proteinMets.mets{i}, 'prot_pool'}; + usageRxns.stoichCoeffs{i} = [1,-1]; + end + usageRxns.lb = zeros(numel(usageRxns.rxns),1); + usageRxns.ub = zeros(numel(usageRxns.rxns),1) + 1000; + usageRxns.rev = ones(numel(usageRxns.rxns),1); + usageRxns.grRules = newEnzymes.genes; + model = addRxns(model,usageRxns); end - usageRxns.lb = zeros(numel(usageRxns.rxns),1); - usageRxns.ub = zeros(numel(usageRxns.rxns),1) + 1000; - usageRxns.rev = ones(numel(usageRxns.rxns),1); - usageRxns.grRules = newEnzymes.genes; - model = addRxns(model,usageRxns); % 5. Update .ec field with enzyme data model.ec.enzymes = [model.ec.enzymes; newEnzymes.enzymes(:)]; @@ -249,8 +261,8 @@ model.ec.eccodes(end+1) = {''}; % Get rules - genes = newRxns.grRules(rxnIdx); - genes = strtrim(erase(split(genes,'and'), {'(' ')'})); + genes = regexp(newRxns.grRules{rxnIdx},'[^\s()]+','match'); % Gene ids and the word 'and', without spaces and brackets + genes = genes(~ismember(lower(genes),{'and','or'})); [~,enzIdx] = ismember(genes, model.ec.genes); % Update the enzyme rxns matrix @@ -260,3 +272,59 @@ rxnsAdded = newRxns.rxns(:); end end + +%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% +%Function that expands a gene rule into disjunctive normal form: a cell array +%with one cell per isozyme, each holding the gene ids that are ANDed in it. +%Gene ids are whole words, so an id that contains 'or' or 'and' is kept +%intact. An empty rule gives an empty cell array. +function dnf = gprToDnf(rule) +tokens = regexp(rule,'\(|\)|[^\s()]+','match'); +isOperator = strcmpi(tokens,'and') | strcmpi(tokens,'or'); +tokens(isOperator) = lower(tokens(isOperator)); % Operators are case insensitive +if isempty(tokens) + dnf = {}; + return +end +[dnf,pos] = parseOr(tokens,1,rule); +if pos <= numel(tokens) + error('Cannot parse the gene rule "%s"',rule) +end +end + +function [dnf,pos] = parseOr(tokens,pos,rule) +[dnf,pos] = parseAnd(tokens,pos,rule); +while pos <= numel(tokens) && strcmp(tokens{pos},'or') + [rhs,pos] = parseAnd(tokens,pos+1,rule); + dnf = [dnf,rhs]; +end +end + +function [dnf,pos] = parseAnd(tokens,pos,rule) +[dnf,pos] = parseAtom(tokens,pos,rule); +while pos <= numel(tokens) && strcmp(tokens{pos},'and') + [rhs,pos] = parseAtom(tokens,pos+1,rule); + product = cell(1,0); + for a = 1:numel(dnf) + for b = 1:numel(rhs) + product{end+1} = [dnf{a},rhs{b}]; %#ok + end + end + dnf = product; +end +end + +function [dnf,pos] = parseAtom(tokens,pos,rule) +if pos > numel(tokens) || any(strcmp(tokens{pos},{')','and','or'})) + error('Cannot parse the gene rule "%s"',rule) +elseif strcmp(tokens{pos},'(') + [dnf,pos] = parseOr(tokens,pos+1,rule); + if pos > numel(tokens) || ~strcmp(tokens{pos},')') + error('Cannot parse the gene rule "%s"',rule) + end + pos = pos + 1; +else + dnf = {tokens(pos)}; + pos = pos + 1; +end +end diff --git a/src/change_model/applyComplexData.m b/src/change_model/applyComplexData.m index b5a60944..2cc17579 100644 --- a/src/change_model/applyComplexData.m +++ b/src/change_model/applyComplexData.m @@ -37,6 +37,11 @@ % % Notes % ----- +% The subunit stoichiometry is assigned per protein ID: the proteins of a +% complex need not be listed in the order of model.ec.enzymes. A subunit with +% stoichiometry 0 has no stated stoichiometry; it counts as a subunit with +% stoichiometry 1. +% % foundComplex and proposedComplex share the following columns: rxn % (reaction identifier), complexID and name (Complex Portal identifiers), % genes (gene names of the complex subunits), protID_model (matched protein @@ -110,9 +115,8 @@ protMatIdx(~isOld) = lastProt+1 : lastProt+numel(newProts); lastProt = lastProt + numel(newProts); % Add subunit numbers - if all(complexData(i).stochiometry == 0) - complexData(i).stochiometry(:) = 1; - end + % A subunit without a stated stoichiometry (0) counts as one subunit + complexData(i).stochiometry(complexData(i).stochiometry == 0) = 1; complexMatrix(i,protMatIdx) = complexData(i).stochiometry; end @@ -154,8 +158,11 @@ foundComplex{foundComplexCount,7} = complexData(complexMatch).stochiometry; % Apply in rxnEnzMat + % The stoichiometry is taken per protein ID, as the proteins of the + % complex need not be listed in the order of model.ec.enzymes [~, modelProtsIdx] = ismember(modelProts, model.ec.enzymes); - model.ec.rxnEnzMat(i,modelProtsIdx) = complexData(complexMatch).stochiometry; + [~, complexPos] = ismember(modelProts, complexData(complexMatch).protID); + model.ec.rxnEnzMat(i,modelProtsIdx) = complexData(complexMatch).stochiometry(complexPos); elseif modComplexUnits > 1 % Only suggest potential complex if grRule > 1 protein moreUnitsInData = find(percMatch == 1 & totalMatch > 1); diff --git a/src/change_model/applyCustomKcats.m b/src/change_model/applyCustomKcats.m index 0cdd5e08..54f9ba67 100644 --- a/src/change_model/applyCustomKcats.m +++ b/src/change_model/applyCustomKcats.m @@ -43,9 +43,13 @@ % - gene_name : short gene name (optional, not used in matching). % - kcat : new kcat value (one per entry). % - rxns : reaction identifiers, multiple for the same kcat are separated by ',' (see further explanation below). -% - notes : will be appended to model.ec.notes (optional). +% - notes : will be appended to model.ec.notes, separated by ', ' from an existing note; an empty note changes nothing (optional). % - stoicho : complex stoichiometry, separated by ' + ' (examples: '1' or '3 + 1'), matching the order in proteins field. % +% An entry with an empty kcat is skipped. Protein and reaction identifiers +% are matched exactly, including their letter case. Light ecModels are +% supported: the rows of model.ec are matched by their ec reaction ids. +% % Matching order: % % 1. reactions are identified by .proteins and .rxns. @@ -121,125 +125,141 @@ enzInModel = cell(length(model.ec.rxns),1); ecRxnNoSuffix = regexprep(model.ec.rxns,'_EXP_\d+$',''); -% Implementation for full GECKO formulation -if ~model.ec.geckoLight - for i = 1:numel(customKcats.proteins) - if isempty(customKcats.proteins{i}) - %If only reaction ID(s) is/are specified (and no proteins), - %then apply the kcat to all isozymic reactions - rxns = strtrim(strsplit(customKcats.rxns{i}, ',')); - rxnIdxs = ismember(ecRxnNoSuffix,rxns); - rxnToUpdate(rxnIdxs) = 1; - model.ec.kcat(rxnIdxs) = customKcats.kcat(i); - - % Add note mentioning manual kcat change - model.ec.source(rxnIdxs) = {'custom'}; - if isfield(customKcats,'notes') - matchedIdxs = find(rxnIdxs); - for j = 1:numel(matchedIdxs) - if isempty(model.ec.notes{matchedIdxs(j), 1}) && ~isempty(customKcats.notes{i}) - model.ec.notes{matchedIdxs(j), 1} = customKcats.notes{i}; - else - model.ec.notes{matchedIdxs(j), 1} = [model.ec.notes{matchedIdxs(j), 1} ', ' customKcats.notes{i}]; - end - end +for i = 1:numel(customKcats.proteins) + if isnan(customKcats.kcat(i)) + printOrange(['WARNING: Entry ' num2str(i) ' has no kcat; it is skipped.']); + continue + end + if isempty(customKcats.proteins{i}) + %If only reaction ID(s) is/are specified (and no proteins), + %then apply the kcat to all isozymic reactions + rxns = strtrim(strsplit(customKcats.rxns{i}, ',')); + rxnIdxs = ismember(ecRxnNoSuffix,rxns); + rxnToUpdate(rxnIdxs) = 1; + model.ec.kcat(rxnIdxs) = customKcats.kcat(i); + + % Add note mentioning manual kcat change + model.ec.source(rxnIdxs) = {'custom'}; + if isfield(customKcats,'notes') + matchedIdxs = find(rxnIdxs); + for j = 1:numel(matchedIdxs) + model.ec.notes{matchedIdxs(j), 1} = appendNote(model.ec.notes{matchedIdxs(j), 1}, customKcats.notes{i}); end + end + else + prots = strtrim(strsplit(customKcats.proteins{i}, '+')); + + % Find the index for the enzymes which kcat will be changed. In + % case the protein is not in the model generate a warning. + try + enzIdx = cellfun(@(x) find(strcmp(model.ec.enzymes, x)), prots); + catch + enzIdx = []; + printOrange(['WARNING: Protein(s) ' customKcats.proteins{i} ' were not found in the model.']); + end + + % if not specific reactions are defined, find all the reaction + % index where the enzyme is used + if isempty(customKcats.rxns{i}) + temp_rxnIdxs = arrayfun(@(x) find(model.ec.rxnEnzMat(:, x)), enzIdx, 'UniformOutput', false); + % otherwhise, If a set of reactions if defined, only get the index for those + % but ignore any _EXP_ suffixes else - prots = strtrim(strsplit(customKcats.proteins{i}, '+')); - - % Find the index for the enzymes which kcat will be changed. In - % case the protein is not in the model generate a warning. - try - enzIdx = cellfun(@(x) find(strcmpi(model.ec.enzymes, x)), prots); - catch - enzIdx = []; - printOrange(['WARNING: Protein(s) ' customKcats.proteins{i} ' were not found in the model.']); - end + rxns = strtrim(strsplit(customKcats.rxns{i}, ',')); + temp_rxnIdxs = cellfun(@(x) find(strcmp(ecRxnNoSuffix, x)), rxns, 'UniformOutput', false); + end - % if not specific reactions are defined, find all the reaction - % index where the enzyme is used - if isempty(customKcats.rxns{i}) - temp_rxnIdxs = arrayfun(@(x) find(model.ec.rxnEnzMat(:, x)), enzIdx, 'UniformOutput', false); - % otherwhise, If a set of reactions if defined, only get the index for those - % but ignore any _EXP_ suffixes - else - rxns = strtrim(strsplit(customKcats.rxns{i}, ',')); - temp_rxnIdxs = arrayfun(@(x) find(strcmpi(ecRxnNoSuffix, x)), rxns, 'UniformOutput', false); + if ~isempty(temp_rxnIdxs) + rxnIdxs = []; + for j = 1:numel(temp_rxnIdxs) + rxnIdxs = [rxnIdxs; temp_rxnIdxs{j}]; end - if ~isempty(temp_rxnIdxs) - rxnIdxs = []; - for j = 1:numel(temp_rxnIdxs) - rxnIdxs = [rxnIdxs; temp_rxnIdxs{j}]; - end + % Check when multiple proteins are involved, since it can return same rxn n times + rxnIdxs = unique(rxnIdxs); %unique(rxnIdxs{1, :}); - % Check when multiple proteins are involved, since it can return same rxn n times - rxnIdxs = unique(rxnIdxs); %unique(rxnIdxs{1, :}); + for j = 1:numel(rxnIdxs) + % Get all the enzymes involved in the reaction + allEnzInRxn = find(model.ec.rxnEnzMat(rxnIdxs(j),:)); - for j = 1:numel(rxnIdxs) - % Get all the enzymes involved in the reaction - allEnzInRxn = find(model.ec.rxnEnzMat(rxnIdxs(j),:)); + C = intersect(enzIdx, allEnzInRxn); - C = intersect(enzIdx, allEnzInRxn); - - % Determine the match percentage bewteen the rules - if numel(C) == numel(enzIdx) && numel(C) == numel(allEnzInRxn) - match = 1; + % Determine the match percentage bewteen the rules + if numel(C) == numel(enzIdx) && numel(C) == numel(allEnzInRxn) + match = 1; + else + if numel(enzIdx) < numel(allEnzInRxn) + match = numel(C) / numel(allEnzInRxn); else - if numel(enzIdx) < numel(allEnzInRxn) - match = numel(C) / numel(allEnzInRxn); - else - match = numel(C) / numel(enzIdx); - end + match = numel(C) / numel(enzIdx); end + end - % Update the kcat value stored in the model, if match 100%, - % otherwhise if >= 0.5 inform to the user to be validated - if match == 1 - rxnToUpdate(rxnIdxs(j)) = 1; - model.ec.kcat(rxnIdxs(j)) = customKcats.kcat(i); - - % Add note mentioning manual kcat change - model.ec.source{rxnIdxs(j),1} = 'custom'; - if isfield(customKcats,'notes') - if isempty(model.ec.notes{rxnIdxs(j), 1}) && ~isempty(customKcats.notes{i}) - model.ec.notes{rxnIdxs(j), 1} = customKcats.notes{i}; - else - model.ec.notes{rxnIdxs(j), 1} = [model.ec.notes{rxnIdxs(j), 1} ', ' customKcats.notes{i}]; - end - end - elseif match >= 0.5 && match < 1 - rxnNotMatch(rxnIdxs(j)) = 1; - evaluatedRule{rxnIdxs(j), 1} = customKcats.proteins{i}; - enzInModel{rxnIdxs(j), 1} = strjoin(model.ec.enzymes(allEnzInRxn), ' + '); + % Update the kcat value stored in the model, if match 100%, + % otherwhise if >= 0.5 inform to the user to be validated + if match == 1 + rxnToUpdate(rxnIdxs(j)) = 1; + model.ec.kcat(rxnIdxs(j)) = customKcats.kcat(i); + + % Add note mentioning manual kcat change + model.ec.source{rxnIdxs(j),1} = 'custom'; + if isfield(customKcats,'notes') + model.ec.notes{rxnIdxs(j), 1} = appendNote(model.ec.notes{rxnIdxs(j), 1}, customKcats.notes{i}); end + elseif match >= 0.5 && match < 1 + rxnNotMatch(rxnIdxs(j)) = 1; + evaluatedRule{rxnIdxs(j), 1} = customKcats.proteins{i}; + enzInModel{rxnIdxs(j), 1} = strjoin(model.ec.enzymes(allEnzInRxn), ' + '); end end end end +end - % Apply the new kcat values to the model - if ~isempty(find(rxnToUpdate, 1)) - model = applyKcatConstraints(model, rxnToUpdate); +% Apply the new kcat values to the model +if ~isempty(find(rxnToUpdate, 1)) + if model.ec.geckoLight + %Light ecModels update by reaction of the model, not by ec row + updateRxns = ismember(model.rxns, extractAfter(model.ec.rxns(rxnToUpdate), 4)); else - printOrange('WARNING: No matches found. Consider checking the IDs or proteins in customKcats.'); + updateRxns = rxnToUpdate; end + model = applyKcatConstraints(model, updateRxns); +else + printOrange('WARNING: No matches found. Consider checking the IDs or proteins in customKcats.'); +end + +rxnUpdated = model.ec.rxns(find(rxnToUpdate)); - rxnUpdated = model.ec.rxns(find(rxnToUpdate)); - - % Remove from notMatch those reactions already updated - remove = and(rxnToUpdate, rxnNotMatch); - rxnNotMatch(remove) = 0; - evaluatedRule(remove) = ''; - enzInModel(remove) = ''; - - idRxns = model.ec.rxns(find(rxnNotMatch)); - fullIdx = cellfun(@(x) find(strcmpi(model.rxns, x)), idRxns); - rxnsNames = model.rxnNames(fullIdx); - evaluatedRule = evaluatedRule(~cellfun('isempty', evaluatedRule)); - enzInModel = enzInModel(~cellfun('isempty', enzInModel)); - rules = model.grRules(fullIdx); - notMatch = table(idRxns, rxnsNames, evaluatedRule, enzInModel, rules, ... - 'VariableNames',{'rxns', 'name', 'custom enzymes', 'enzymes in model', 'rules'}); +% Remove from notMatch those reactions already updated +remove = and(rxnToUpdate, rxnNotMatch); +rxnNotMatch(remove) = 0; +evaluatedRule(remove) = ''; +enzInModel(remove) = ''; + +idRxns = model.ec.rxns(find(rxnNotMatch)); +if model.ec.geckoLight + modelRxnIds = extractAfter(idRxns, 4); +else + modelRxnIds = idRxns; +end +fullIdx = cellfun(@(x) find(strcmpi(model.rxns, x), 1), modelRxnIds); +rxnsNames = model.rxnNames(fullIdx); +evaluatedRule = evaluatedRule(~cellfun('isempty', evaluatedRule)); +enzInModel = enzInModel(~cellfun('isempty', enzInModel)); +rules = model.grRules(fullIdx); +notMatch = table(idRxns, rxnsNames, evaluatedRule, enzInModel, rules, ... + 'VariableNames',{'rxns', 'name', 'custom enzymes', 'enzymes in model', 'rules'}); +end + +function notes = appendNote(notes, note) +% An empty note changes nothing; a note is separated by ', ' from an existing one. +note = strtrim(note); +if isempty(note) + return +elseif isempty(notes) + notes = note; +else + notes = [notes ', ' note]; end end diff --git a/src/change_model/applyKcatConstraints.m b/src/change_model/applyKcatConstraints.m index d8c25de2..1edabd5e 100644 --- a/src/change_model/applyKcatConstraints.m +++ b/src/change_model/applyKcatConstraints.m @@ -3,7 +3,8 @@ % % Existing enzyme constraints are first removed (unless updateRxns is % provided), and new constraints are defined based on the content of -% model.ec.kcat. +% model.ec.kcat. When every kcat is 0, the existing constraints are removed +% and no new ones are written. % % Parameters % ---------- @@ -16,8 +17,13 @@ % if not all enzyme constraints should be updated, this can be given as % either a logical vector of length model.ec.rxns, a vector of % model.ec.rxns indices, or a (cell array of) string(s) with -% model.ec.rxns identifiers. For light models, these reactions should -% match model.rxns. +% model.ec.rxns identifiers. For light models, a (cell array of) string(s) +% may hold reaction identifiers of model.rxns or of model.ec.rxns (with +% the ###_ prefix); a reaction is then updated as a whole, with all its +% isozymes. An identifier that is in both or in neither raises the +% error applyKcatConstraints:ambiguousReaction or +% applyKcatConstraints:unknownReaction. A logical vector or indices +% refer to model.rxns for light models. % % Returns % ------- @@ -54,6 +60,23 @@ updateRxns = updateRxnsLog; elseif iscellstr(updateRxns) || ischar(updateRxns) || isstring(updateRxns) updateRxnsIds = convertCharArray(updateRxns); + updateRxnsIds = updateRxnsIds(:); + if model.ec.geckoLight + isCobra = ismember(updateRxnsIds,model.rxns); + isEc = ismember(updateRxnsIds,model.ec.rxns); + if any(isCobra & isEc) + error('applyKcatConstraints:ambiguousReaction', ... + 'The identifiers %s are in both model.rxns and model.ec.rxns.', ... + strjoin(updateRxnsIds(isCobra & isEc),', ')) + end + if any(~isCobra & ~isEc) + error('applyKcatConstraints:unknownReaction', ... + 'The identifiers %s are in neither model.rxns nor model.ec.rxns.', ... + strjoin(updateRxnsIds(~isCobra & ~isEc),', ')) + end + updateRxnsIds = [updateRxnsIds(isCobra); extractAfter(updateRxnsIds(isEc),4)]; + updateRxnsIds = updateRxnsIds(:); + end updateRxns = ismember(rxns,updateRxnsIds); end @@ -66,8 +89,9 @@ ' not a valid GECKO3 ecModel. First run makeEcModel(model).']) end if all(model.ec.kcat==0) - printOrange('WARNING: No kcat values are provided in model.ec.kcat, model remains unchanged.\n'); - return + % The existing enzyme constraints of the selected reactions are still + % cleared below, and no new ones are written. + printOrange('WARNING: No kcat values are provided in model.ec.kcat, existing enzyme constraints are cleared and no new ones are written.\n'); end %Clear existing incorporation of enzyme usage @@ -135,12 +159,17 @@ % summed per reaction), and divide by their kcat, to get a vector % of MW/kcat values. MWkcat = (model.ec.rxnEnzMat(ecIdx,:) * model.ec.mw) ./ model.ec.kcat(ecIdx); - % If kcat was zero, MWkcat is Inf. If no enzyme info was found, - % MWkcat is NaN. Drop those isozymes *before* selecting the - % cheapest one: correcting them to zero and including them in the - % min() below would let an isozyme with no kcat assigned always - % win over a real kcat on another isozyme of the same reaction. - validKcat = ~isinf(MWkcat) & ~isnan(MWkcat); + % If kcat was zero, MWkcat is Inf (or NaN without enzymes). An + % isozyme row without any enzyme has MWkcat zero. Drop those + % isozymes *before* selecting the cheapest one: including them in + % the min() below would let an isozyme with no kcat or no enzyme + % always win over a real kcat on another isozyme of the same reaction. + % A row with a kcat that is not positive or an enzyme mass that is not + % positive has no usable cost either. + hasEnzyme = full(sum(model.ec.rxnEnzMat(ecIdx,:) ~= 0,2)) > 0; + enzMass = full(model.ec.rxnEnzMat(ecIdx,:) * model.ec.mw); + validKcat = ~isinf(MWkcat) & ~isnan(MWkcat) & hasEnzyme & ... + model.ec.kcat(ecIdx) > 0 & enzMass > 0; if any(validKcat) % Select the lowest MW/kcat (= most efficient), and convert to /hour model.S(prot_pool_idx, hasEc(i)) = -min(MWkcat(validKcat)/3600); diff --git a/src/change_model/findMetSmiles.m b/src/change_model/findMetSmiles.m index 616f1caf..55f4f94b 100644 --- a/src/change_model/findMetSmiles.m +++ b/src/change_model/findMetSmiles.m @@ -3,7 +3,10 @@ % % Matches are cached in tutorials/***/data/smilesDB.tsv, which is checked % first on subsequent runs so repeated queries are avoided. If the model -% already has a metSmiles field, non-empty entries are left unchanged. +% already has a metSmiles field, non-empty entries are left unchanged. When +% the cache holds a name more than once, the last row is used. A metabolite +% without a name is skipped with a warning (findMetSmiles:emptyName) and +% gets no SMILES. % % Parameters % ---------- @@ -39,6 +42,10 @@ end params = modelAdapter.params; +nEmpty = sum(cellfun(@isempty,model.metNames)); +if nEmpty > 0 + warning('findMetSmiles:emptyName','%d metabolite(s) have no name and get no SMILES.',nEmpty) +end [uniqueNames, ~, uniqueIdx] = unique(regexprep(model.metNames,'^prot_.*','')); uniqueSmiles(1:numel(uniqueNames),1) = {''}; metMatch = false(length(uniqueNames),1); @@ -49,8 +56,9 @@ fID = fopen(smilesDBfile,'r'); raw = textscan(fID,'%s %s','Delimiter','\t','HeaderLines',0); fclose(fID); - smilesDB.names = raw{1}; - smilesDB.smile = raw{2}; + %The last row of a name that occurs more than once is used + smilesDB.names = flipud(raw{1}); + smilesDB.smile = flipud(raw{2}); [metMatch, metIdx] = ismember(uniqueNames,smilesDB.names); uniqueSmiles(metMatch) = smilesDB.smile(metIdx(metMatch)); if verbose; fprintf('done.\n'); end diff --git a/src/change_model/getKcatAcrossIsozymes.m b/src/change_model/getKcatAcrossIsozymes.m index 47c03664..71dfe485 100644 --- a/src/change_model/getKcatAcrossIsozymes.m +++ b/src/change_model/getKcatAcrossIsozymes.m @@ -4,7 +4,9 @@ % For reactions without kcat value (0 in model.ec.kcat), isozymes are found % (being based on the same reaction in the conventional GEM), that do have a % kcat value assigned. The mean kcat value of these isozymes is then used to -% fill in model.ec.kcat. +% fill in model.ec.kcat. Only isozymes with a kcat above 0 enter the mean: a +% NaN or negative kcat of an isozyme is left out, and an entry whose kcat is +% NaN is not filled. % % Parameters % ---------- @@ -34,10 +36,11 @@ end noKcats = model.ec.kcat==0; +hasKcat = model.ec.kcat>0; % NaN and negative kcats are not isozyme values rxnIDs = regexprep(model.ec.rxns,'_EXP_\d+',''); noKcatID = rxnIDs(noKcats); -yesKcatID = rxnIDs(~noKcats); -yesKcatVal = model.ec.kcat(~noKcats); +yesKcatID = rxnIDs(hasKcat); +yesKcatVal = model.ec.kcat(hasKcat); noKcatVal = cellfun(@(x) strcmp(x, yesKcatID), noKcatID, 'UniformOutput', false); noKcatVal = cell2mat(cellfun(@(x) mean(yesKcatVal(x)), noKcatVal, 'UniformOutput', false)); diff --git a/src/change_model/getSubsetEcModel.m b/src/change_model/getSubsetEcModel.m index d7f484ed..ae09990c 100644 --- a/src/change_model/getSubsetEcModel.m +++ b/src/change_model/getSubsetEcModel.m @@ -50,7 +50,11 @@ if ismember('standard', genesToRemove) genesToRemove(strcmp(genesToRemove, 'standard')) = []; end -smallEcModel = removeGenes(bigEcModel,genesToRemove,true,true,false); +if isempty(genesToRemove) + smallEcModel = bigEcModel; +else + smallEcModel = removeGenes(bigEcModel,genesToRemove,true,true,false); +end % Remove genes from ec-structure enzToRemove = ismember(smallEcModel.ec.genes,genesToRemove); @@ -68,7 +72,13 @@ smallEcModel = removeReactions(smallEcModel,~keepRxns, true, true, true); % Remove reactions from ec-structure -ecRxnsToRemove = ~ismember(smallEcModel.ec.rxns,smallEcModel.rxns); +% The reaction identifiers of a light ecModel carry a 4 character prefix +if smallEcModel.ec.geckoLight + ecModelRxns = extractAfter(smallEcModel.ec.rxns,4); +else + ecModelRxns = smallEcModel.ec.rxns; +end +ecRxnsToRemove = ~ismember(ecModelRxns,smallEcModel.rxns); smallEcModel.ec.rxns(ecRxnsToRemove) = []; smallEcModel.ec.kcat(ecRxnsToRemove) = []; diff --git a/src/change_model/makeEcModel.m b/src/change_model/makeEcModel.m index f8662b7e..313e1c0d 100644 --- a/src/change_model/makeEcModel.m +++ b/src/change_model/makeEcModel.m @@ -226,10 +226,13 @@ else %Different strategy for GECKO light: Each reaction can exist multiple times in %ec.rxns and similar fields - one time per isozyme. The number of copies is - %the number of ORs in the GPR + 1 - numOrs = count(model.grRules(rxnWithGene), ' or '); - cpys = numOrs + 1; - prevNumRxns = length(numOrs); + %the number of AND-clauses of the GPR in disjunctive normal form, so + %'G1 and (G2 or G3)' gives the isozymes {G1,G2} and {G1,G3}. + isozymes = cellfun(@gprToDnf, model.grRules(rxnWithGene), 'UniformOutput', false); + % A reaction with gene entries but an empty rule keeps one isozyme without enzymes + isozymes(cellfun(@isempty,isozymes)) = {{cell(1,0)}}; + cpys = cellfun(@numel, isozymes); + prevNumRxns = numel(isozymes); cpyIndices = repelem(rxnWithGene, cpys).'; %.' only matter when number of rxns is 1 %loop through and add a prefix with an isozyme index to the rxns %we just give a fixed-length number as prefix, and assume that 999 is enough @@ -362,51 +365,18 @@ for r=1:numel(rxnWithGene) rxnGenes = model.genes(find(model.rxnGeneMat(rxnWithGene(r),:))); [~,locEnz] = ismember(rxnGenes,ec.genes); % Could also parse directly from rxnGeneMat, but some genes might be missing from Uniprot DB - if locEnz ~= 0 - ec.rxnEnzMat(r,locEnz) = 1; %Assume 1 copy per subunit or enzyme, can be modified later - end + locEnz = locEnz(locEnz ~= 0); % Subunits missing from the databases are left out; the others still couple the reaction + ec.rxnEnzMat(r,locEnz) = 1; %Assume 1 copy per subunit or enzyme, can be modified later end else %For light models, we need to split up all GPRs ec.rxnEnzMat = zeros(numel(ec.rxns),numel(ec.genes)); % Non-zeros will indicate the number of subunits nextIndex = 1; - %For full model generation, the GPRs are controlled in expandModel, but - %here we need to make an explicit format check - indexes2check = findPotentialErrors(model.grRules,model); - if ~isempty(indexes2check) - printOrange('Run standardizeGrRules(model) for a more detailed warning.\n'); - printOrange('For Human-GEM, these reactions can be corrected using simplifyGrRules.\n'); - end - for i=1:prevNumRxns - %ind is the index in the model, not to confuse with the index in the ec struct (i), - %which only contains reactions with GPRs. - ind = rxnWithGene(i); - %Get rid of all '(' and ')' since I'm not looking at complex stuff - %anyways - geneString=model.grRules{ind}; - geneString=strrep(geneString,'(',''); - geneString=strrep(geneString,')',''); - geneString=strrep(geneString,' or ',';'); - - if (numOrs(i) == 0) - geneNames = {geneString}; - else - %Split the string into gene names - geneNames=regexp(geneString,';','split'); - end - - %Now loop through the isozymes and set the rxnGeneMat - for j = 1:length(geneNames) - %Find the gene in the gene list If ' and ' relationship, first - %split the genes - fnd = strfind(geneNames{j},' and '); - if ~isempty(fnd) - andGenes=regexp(geneNames{j},' and ','split'); - ec.rxnEnzMat(nextIndex,ismember(ec.genes,andGenes)) = 1; %should be subunit stoichoimetry - else - ec.rxnEnzMat(nextIndex,ismember(ec.genes,geneNames(j)))=1;%should be subunit stoichoimetry - end + %Each isozyme is one AND-clause of the GPR and gets its own row of + %ec.rxnEnzMat, in the order of the copies of the reaction in ec.rxns. + for j = 1:numel(isozymes{i}) + ec.rxnEnzMat(nextIndex,ismember(ec.genes,isozymes{i}{j})) = 1;%should be subunit stoichoimetry nextIndex = nextIndex + 1; end end @@ -485,23 +455,57 @@ end %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% -%Function that gets the model field grRules and returns the indexes of the -%rules in which the pattern ") and (" is present. -%Copied from standardizeGrRules -% TODO: Make this an accessible function in a separate file in RAVEN and remove this -%implementation. -function indexes2check = findPotentialErrors(grRules,model) -indxs_l = find(~cellfun(@isempty,strfind(grRules,') and ('))); -indxs_l_L = find(~cellfun(@isempty,strfind(grRules,') and'))); -indxs_l_R = find(~cellfun(@isempty,strfind(grRules,'and ('))); -indexes2check = vertcat(indxs_l,indxs_l_L,indxs_l_R); -indexes2check = unique(indexes2check); - -if ~isempty(indexes2check) - textToPrint = 'WARNING: Potentially problematic ") AND (" in the grRules for reaction(s):\n'; - for i=1:numel(indexes2check) - textToPrint=[textToPrint '\t' model.rxns{indexes2check(i)} '\n']; +%Function that expands a gene rule into disjunctive normal form: a cell array +%with one cell per isozyme, each holding the gene ids that are ANDed in it. +%Gene ids are whole words, so an id that contains 'or' or 'and' is kept +%intact. An empty rule gives an empty cell array. +function dnf = gprToDnf(rule) +tokens = regexp(rule,'\(|\)|[^\s()]+','match'); +isOperator = strcmpi(tokens,'and') | strcmpi(tokens,'or'); +tokens(isOperator) = lower(tokens(isOperator)); % Operators are case insensitive +if isempty(tokens) + dnf = {}; + return +end +[dnf,pos] = parseOr(tokens,1,rule); +if pos <= numel(tokens) + error('Cannot parse the gene rule "%s"',rule) +end +end + +function [dnf,pos] = parseOr(tokens,pos,rule) +[dnf,pos] = parseAnd(tokens,pos,rule); +while pos <= numel(tokens) && strcmp(tokens{pos},'or') + [rhs,pos] = parseAnd(tokens,pos+1,rule); + dnf = [dnf,rhs]; +end +end + +function [dnf,pos] = parseAnd(tokens,pos,rule) +[dnf,pos] = parseAtom(tokens,pos,rule); +while pos <= numel(tokens) && strcmp(tokens{pos},'and') + [rhs,pos] = parseAtom(tokens,pos+1,rule); + product = cell(1,0); + for a = 1:numel(dnf) + for b = 1:numel(rhs) + product{end+1} = [dnf{a},rhs{b}]; %#ok + end end - printOrange(textToPrint); + dnf = product; +end +end + +function [dnf,pos] = parseAtom(tokens,pos,rule) +if pos > numel(tokens) || any(strcmp(tokens{pos},{')','and','or'})) + error('Cannot parse the gene rule "%s"',rule) +elseif strcmp(tokens{pos},'(') + [dnf,pos] = parseOr(tokens,pos+1,rule); + if pos > numel(tokens) || ~strcmp(tokens{pos},')') + error('Cannot parse the gene rule "%s"',rule) + end + pos = pos + 1; +else + dnf = {tokens(pos)}; + pos = pos + 1; end end diff --git a/src/change_model/mapRxnsToConv.m b/src/change_model/mapRxnsToConv.m index e68f3dff..ee599626 100644 --- a/src/change_model/mapRxnsToConv.m +++ b/src/change_model/mapRxnsToConv.m @@ -43,11 +43,12 @@ rxnIDs = ecModel.rxns; % Invert flux of _REV reactions -revRxns = endsWith(rxnIDs,'_REV') | contains(rxnIDs,'_REV_EXP_'); +% The suffixes are added in the order _REV, _EXP_n, so strip _EXP_n first and +% then _REV, each only at the end of the id (an id like R_REVX is left intact). +rxnIDs = regexprep(rxnIDs,'_EXP_\d+$',''); +revRxns = endsWith(rxnIDs,'_REV'); fluxes(revRxns,:) = -fluxes(revRxns,:); -rxnIDs(revRxns) = replace(rxnIDs(revRxns),'_REV',''); -% Remove _EXP_. suffixes -rxnIDs = regexprep(rxnIDs,'_EXP_\d+',''); +rxnIDs(revRxns) = regexprep(rxnIDs(revRxns),'_REV$',''); % Map and sum fluxes to converted reaction IDs [rxnIDmap, convRxnID] = findgroups(rxnIDs); diff --git a/src/change_model/upgradeEcModel.m b/src/change_model/upgradeEcModel.m new file mode 100644 index 00000000..318ff104 --- /dev/null +++ b/src/change_model/upgradeEcModel.m @@ -0,0 +1,63 @@ +function [model, changed] = upgradeEcModel(model) +% upgradeEcModel Bring an ecModel made with GECKO 3 to the GECKO 4 format. +% +% GECKO 3 defined the protein usage reactions (usage_prot_, prot_ +% -> prot_pool) and the protein pool exchange (prot_pool_exchange, +% prot_pool ->) in the reverse direction, used with negative flux. GECKO 4 +% defines them forward (prot_pool -> prot_, -> prot_pool), so that an +% enzyme's usage is the positive flux of its usage reaction. This turns +% each reaction that is still reverse: its column of S, its bounds and its +% objective coefficient change sign. Reactions already forward are left as +% they are, so calling it again changes nothing. Flux values of the model +% (fluxes of usage reactions and the pool exchange) change sign with it. +% The ecModel format (annotation.gecko_format, see saveEcModel) becomes 4 +% when it is missing or lower. +% geckopy has the same (upgrade_ec_model). +% +% Parameters +% ---------- +% model : struct +% an ecModel. +% +% Returns +% ------- +% model : struct +% the ecModel in the GECKO 4 format. +% changed : cell +% the reactions that were turned. +% +% Examples +% -------- +% ecModel = upgradeEcModel(readYAMLmodel('ecYeastGEM_GECKO3.yml')); +% +% See also +% -------- +% upgradeGECKOproject, makeEcModel, setProtPoolSize + +pool = find(strcmp(model.mets, 'prot_pool')); +changed = {}; +if isempty(pool) + return +end +if ~isfield(model, 'annotation') || ~isfield(model.annotation, 'gecko_format') ... + || str2double(model.annotation.gecko_format) < 4 + model.annotation.gecko_format = '4'; +end +usage = find(startsWith(model.rxns, 'usage_prot_')); +reverse = usage(full(model.S(pool, usage)) > 0); +exchange = find(strcmp(model.rxns, 'prot_pool_exchange')); +if ~isempty(exchange) && full(model.S(pool, exchange)) < 0 + reverse(end+1, 1) = exchange; +end +if isempty(reverse) + return +end +model.S(:, reverse) = -model.S(:, reverse); +lb = model.lb(reverse); +model.lb(reverse) = -model.ub(reverse); +model.ub(reverse) = -lb; +if isfield(model, 'c') + model.c(reverse) = -model.c(reverse); +end +changed = model.rxns(reverse); +end diff --git a/src/download_databases/fetchBrendaAsset.m b/src/download_databases/fetchBrendaAsset.m new file mode 100644 index 00000000..1672a6b3 --- /dev/null +++ b/src/download_databases/fetchBrendaAsset.m @@ -0,0 +1,62 @@ +function folder = fetchBrendaAsset(files) +% fetchBrendaAsset Download (once) GECKO's BRENDA files and return their folder. +% +% GECKO does not ship BRENDA data. The files of the toolbox-assets release +% brenda-2026.1-1 (BRENDA 2026.1, CC BY 4.0) are downloaded on first use +% with RAVEN's fetchToolboxAsset, which checks them against the checksums +% of the toolbox-assets manifest, and are unpacked into +% databases/brenda-2026.1-1 in the GECKO folder. geckopy reads the same +% release (fetch_brenda_asset). A project can use its own BRENDA files +% instead, in data/brenda (see ModelAdapter.getBrendaDBFolder). +% +% Parameters +% ---------- +% files : cell +% file names (default: kcat.tsv, sa.tsv, mw.tsv and measurements.tsv); +% the release also has sequences.fasta, substrates.tsv and +% kcatCombineParams.tsv. +% +% Returns +% ------- +% folder : char +% the folder with the files, unpacked. +% +% Examples +% -------- +% folder = fetchBrendaAsset(); +% folder = fetchBrendaAsset({'kcatCombineParams.tsv'}); +% +% See also +% -------- +% loadBRENDAdata, loadBrendaMeasurements, ModelAdapter + +release = 'brenda-2026.1-1'; +if nargin < 1 || isempty(files) + files = {'kcat.tsv', 'sa.tsv', 'mw.tsv', 'measurements.tsv'}; +end +files = cellstr(files); +packed = struct('kcat_tsv', 1, 'sa_tsv', 1, 'mw_tsv', 1, 'measurements_tsv', 1, ... + 'sequences_fasta', 1, 'substrates_tsv', 1, 'kcatCombineParams_tsv', 0); +folder = fullfile(findGECKOroot(), 'databases', release); +if exist('fetchToolboxAsset', 'file') ~= 2 + error('fetchBrendaAsset:raven', ['GECKO downloads its BRENDA files with RAVEN''s ' ... + 'fetchToolboxAsset, which this RAVEN does not have. Update RAVEN to version 3.']) +end +for i = 1:numel(files) + name = files{i}; + key = matlab.lang.makeValidName(name); + if ~isfield(packed, key) + error('fetchBrendaAsset:file', '%s is not a file of %s.', name, release) + end + target = fullfile(folder, name); + if isfile(target) + continue + end + if packed.(key) + gz = fetchToolboxAsset(folder, release, [name '.gz']); + gunzip(gz, folder); + else + fetchToolboxAsset(folder, release, name); + end +end +end diff --git a/src/download_databases/loadBRENDAdata.m b/src/download_databases/loadBRENDAdata.m index 58fe1b44..07a96db4 100644 --- a/src/download_databases/loadBRENDAdata.m +++ b/src/download_databases/loadBRENDAdata.m @@ -8,14 +8,29 @@ % molecular weights). % % kcat.tsv and sa.tsv each carry both a max and a median aggregate per -% (EC, substrate, organism) triple; only the max column is used here. Each -% file starts with a `#`-prefixed release-version line followed by a -% tab-delimited column header, both skipped on read. +% (EC, substrate, organism) triple; kcatAggregation selects which of the +% two is read. Each file starts with a `#`-prefixed release-version line +% followed by a tab-delimited column header, both skipped on read. % % Name-Value Arguments % -------------------- % modelAdapter : ModelAdapter % a loaded model adapter (default: the current default model adapter). +% kcatAggregation : char +% which aggregate to read from kcat.tsv and sa.tsv, 'max' or +% 'median' (default: params.kcatAggregation from the model adapter, +% or 'max' if the adapter does not set it). A triple's max is the +% highest turnover reported for it; its median is the middle one. +% filterOutlierKcats : logical +% whether to drop a row whose kcat is implausibly low for its EC +% (default: true). A row is dropped when its kcat is more than four +% orders of magnitude below the median kcat of its EC. The reference +% median of an EC is taken over the positive kcat values of the max and +% median views of kcat.tsv and of the kcat values derived from sa.tsv +% and mw.tsv, before any row is dropped, so it does not depend on +% kcatAggregation. Wildcard ECs (containing '-') do not contribute to a +% reference. The EC level widens from w.x.y.z to w.x.y, w.x and w while +% fewer than five values are available. Set to false to keep every row. % % Returns % ------- @@ -29,14 +44,28 @@ % % optional arguments may be given positionally or as name-value pairs: % [KCATcell, SAcell] = loadBRENDAdata(); % [KCATcell, SAcell] = loadBRENDAdata('modelAdapter', adapter); +% [KCATcell, SAcell] = loadBRENDAdata('kcatAggregation', 'median'); +% [KCATcell, SAcell] = loadBRENDAdata('filterOutlierKcats', false); % % See also % -------- % loadDatabases, getECfromDatabase p = parseGECKOargs(varargin, { ... - 'modelAdapter', []}); -modelAdapter = p.modelAdapter; + 'modelAdapter', [], @(x) assert(isempty(x) || isa(x,'ModelAdapter'), ... + 'loadBRENDAdata:invalidModelAdapter', ... + 'modelAdapter must be a ModelAdapter.'); ... + 'kcatAggregation', [], @(x) assert(isempty(x) || any(strcmpi(x, ... + {'max','median'})), ... + 'loadBRENDAdata:invalidKcatAggregation', ... + 'kcatAggregation must be ''max'' or ''median''.'); ... + 'filterOutlierKcats', true, @(x) assert((islogical(x) || isnumeric(x)) && ... + isscalar(x), ... + 'loadBRENDAdata:invalidFilterOutlierKcats', ... + 'filterOutlierKcats must be a logical scalar.')}); +modelAdapter = p.modelAdapter; +kcatAggregation = p.kcatAggregation; +filterOutlierKcats = logical(p.filterOutlierKcats); if isempty(modelAdapter) modelAdapter = ModelAdapterManager.getDefault(); @@ -45,6 +74,11 @@ end end +kcatAggregation = resolveKcatAggregation(kcatAggregation, modelAdapter); +%Column 4 holds the per-triple maximum and column 5 the median; both are +%read, so that the outlier filter can use the max and the median views. +valueCol = 4 + strcmpi(kcatAggregation,'median'); + basePath = modelAdapter.getBrendaDBFolder(); KCAT_file = fullfile(basePath,'kcat.tsv'); SA_file = fullfile(basePath,'sa.tsv'); @@ -52,31 +86,31 @@ %Extract BRENDA DATA from files information. kcat.tsv/sa.tsv are seven %columns (ec_code, substrate, organism, value_max, value_median, n, -%references); the max column (4) is used. mw.tsv is six columns (no -%substrate-level aggregation choice): ec_code, substrate, organism, value, -%n, references. -KCATcell = openDataFile(KCAT_file,1,'%q %q %q %f %f %f %q',4); +%references); the data cells hold ec_code, substrate, organism, the max and +%the median. mw.tsv is six columns (no substrate-level aggregation choice): +%ec_code, substrate, organism, value, n, references. +KCAT = openDataFile(KCAT_file,1,'%q %q %q %f %f %f %q',[4 5]); scalingFactor = 1/60; %[umol/min/mg] -> [mmol/s/g] -SA = openDataFile(SA_file,scalingFactor,'%q %q %q %f %f %f %q',4); +SA = openDataFile(SA_file,scalingFactor,'%q %q %q %f %f %f %q',[4 5]); scalingFactor = 1/1000; %[g/mol] -> [g/mmol] MW = openDataFile(MW_file,scalingFactor,'%q %q %q %f %f %q',4); -for i=1:4 - SAcell{i} = []; -end -previousEC = []; EC_indexes = []; - %build an index on MW{1} to speed things up a bit %first just extract the genus (i.e. the first part of the name) -MWECNum = upper(unique(MW{1})); +MWECNum = unique(upper(MW{1})); MWECNumIndices = cell(length(MWECNum),1); MWECNumHashMap = containers.Map(MWECNum,1:length(MWECNum)); for i = 1:length(MW{1}) - matchInd = cell2mat(values(MWECNumHashMap, MW{1}(i))); + matchInd = cell2mat(values(MWECNumHashMap, upper(MW{1}(i)))); MWECNumIndices{matchInd} = [MWECNumIndices{matchInd};i]; end - +%Match each specific activity to the molecular weight of its EC and +%organism. The first match is used. +previousEC = []; EC_indexes = []; +saRows = zeros(length(SA{1}),1); +mwVals = zeros(length(SA{1}),1); +nMatched = 0; for i=1:length(SA{1}) %Gets the indexes of the EC repetitions in the MW cell for every %new (different) EC @@ -94,18 +128,85 @@ % each EC# / Orgaism is reported on the file org_index = find(strcmpi(SA{3}(i),mwEC{1}),1); if ~isempty(org_index) - SAcell{1} = [SAcell{1};SA{1}(i)]; - SAcell{2} = [SAcell{2};SA{3}(i)]; - SAcell{3} = [SAcell{3}; SA{4}(i)*mwEC{2}(org_index)]; %[1/s] - SAcell{4} = [SAcell{4}; mwEC{2}(org_index)]; + nMatched = nMatched + 1; + saRows(nMatched) = i; + mwVals(nMatched) = mwEC{2}(org_index); end previousEC = SA{1}(i); end +saRows = saRows(1:nMatched); +mwVals = mwVals(1:nMatched); + +%Specific activities as kcat values [1/s], for the max and the median +saEC = SA{1}(saRows); +saMax = SA{4}(saRows).*mwVals; +saMedian = SA{5}(saRows).*mwVals; -function data_cell = openDataFile(fileName,scalingFactor,formatSpec,valueCol) +if valueCol == 4 + saSelected = saMax; +else + saSelected = saMedian; +end + +%Drop kcats that are implausibly low for their EC +keepKcat = true(size(KCAT{1})); +keepSA = true(size(saEC)); +if filterOutlierKcats + ecPool = [KCAT{1}; KCAT{1}; saEC; saEC]; + valPool = [KCAT{4}; KCAT{5}; saMax; saMedian]; + keepKcat = ~isOutlier(KCAT{1},KCAT{valueCol},ecPool,valPool); + keepSA = ~isOutlier(saEC,saSelected,ecPool,valPool); +end + +KCATcell = {KCAT{1}(keepKcat), KCAT{2}(keepKcat), KCAT{3}(keepKcat), ... + KCAT{valueCol}(keepKcat)}; +if nMatched > 0 + SAcell = {saEC(keepSA), SA{3}(saRows(keepSA)), saSelected(keepSA), ... + mwVals(keepSA)}; +else + SAcell = {[],[],[],[]}; +end +end + +function data_cell = openDataFile(fileName,scalingFactor,formatSpec,valueCols) fID = fopen(fileName); raw = textscan(fID,formatSpec,'delimiter','\t','HeaderLines',2); fclose(fID); -data_cell = {raw{1}, raw{2}, raw{3}, raw{valueCol}*scalingFactor}; +data_cell = [raw(1:3), cellfun(@(c) raw{c}*scalingFactor, num2cell(valueCols), ... + 'UniformOutput', false)]; end + +function outlier = isOutlier(ecs,vals,ecPool,valPool) +%A value is an outlier if it is more than 'decades' orders of magnitude below +%the median kcat of its own EC, taken over the pool of values. The EC widens +%from the full code to its 3-, 2- and 1-level prefix while fewer than minRef +%values are available. +decades = 4; +minRef = 5; +usePool = valPool > 0 & ~contains(ecPool,'-'); +ecPool = ecPool(usePool); +logPool = log10(valPool(usePool)); +refLog = NaN(size(ecs)); +if isempty(ecs) || isempty(logPool) + outlier = false(size(ecs)); + return +end +for level = 4:-1:1 + poolKey = ecPrefix(ecPool,level); + [grp,keys] = findgroups(poolKey); + nPerKey = accumarray(grp,1); + medPerKey = splitapply(@median,logPool,grp); + [found,loc] = ismember(ecPrefix(ecs,level),keys); + use = isnan(refLog) & found; + use(use) = nPerKey(loc(use)) >= minRef; + refLog(use) = medPerKey(loc(use)); +end +outlier = vals > 0 & ~isnan(refLog) & log10(vals) < refLog - decades; +end + +function prefix = ecPrefix(ecs,level) +%The first 'level' dot-separated parts of each EC code +prefix = regexp(ecs,['^[^.]*(?:\.[^.]*){0,' num2str(level-1) '}'],'match','once'); +prefix(cellfun(@isempty,prefix)) = {''}; +prefix = reshape(prefix,size(ecs)); end diff --git a/src/download_databases/resolveKcatAggregation.m b/src/download_databases/resolveKcatAggregation.m new file mode 100644 index 00000000..9729e812 --- /dev/null +++ b/src/download_databases/resolveKcatAggregation.m @@ -0,0 +1,42 @@ +%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% +function kcatAggregation = resolveKcatAggregation(kcatAggregation, modelAdapter) +% resolveKcatAggregation Settle which BRENDA aggregate to read. +% +% The BRENDA snapshot records both a maximum and a median per +% (EC, substrate, organism) triple. Which one a run uses can be given per +% call, or once on the model adapter as params.kcatAggregation; an +% adapter that sets neither gets 'max', which is what GECKO has always +% used. +% +% Input Arguments +% --------------- +% kcatAggregation : char +% the per-call choice, or empty to fall back to the adapter. +% modelAdapter : ModelAdapter +% a loaded model adapter. +% +% Returns +% ------- +% kcatAggregation : char +% 'max' or 'median'. +% +% See also +% -------- +% loadBRENDAdata, fuzzyKcatMatching + +if isempty(kcatAggregation) + params = modelAdapter.getParameters(); + if isfield(params,'kcatAggregation') && ~isempty(params.kcatAggregation) + kcatAggregation = params.kcatAggregation; + else + kcatAggregation = 'max'; + end +end + +if ~(ischar(kcatAggregation) || isstring(kcatAggregation)) || ... + ~any(strcmpi(kcatAggregation,{'max','median'})) + error('resolveKcatAggregation:invalidKcatAggregation', ... + 'kcatAggregation must be ''max'' or ''median''.') +end +kcatAggregation = lower(char(kcatAggregation)); +end diff --git a/src/enzyme_usage/getEnzymeBottlenecks.m b/src/enzyme_usage/getEnzymeBottlenecks.m index f345476f..83f6dbe5 100644 --- a/src/enzyme_usage/getEnzymeBottlenecks.m +++ b/src/enzyme_usage/getEnzymeBottlenecks.m @@ -1,9 +1,20 @@ function bottlenecks = getEnzymeBottlenecks(model, varargin) % getEnzymeBottlenecks Top-N enzymes limiting the current objective. % -% Solves the model and ranks every enzyme by the absolute shadow price of -% its prot_ mass-balance constraint --- the enzymes whose extra -% availability would help the objective the most. +% Solves the model and ranks every enzyme by the change of the objective +% after the upper bound of its usage_prot_ reaction is raised by +% foldChange and the model is solved again. The objective is maximised, so +% the gain is the rise of the maximised objective. Only enzymes whose usage runs at +% its upper bound are solved again; raising a bound that does not bind +% cannot change the optimum, so every other enzyme has an objectiveGain of 0 +% without a solve. +% +% The shadow price of the prot_ mass-balance constraint is reported for +% reference and does not enter the order: at a degenerate optimum, which is +% common in enzyme-constrained models, several constraints are active and +% the solver assigns the dual to one of them depending on the basis. +% Enzymes with equal objectiveGain (rounded to 9 decimals) keep their order +% in model.ec.enzymes. % % Parameters % ---------- @@ -16,31 +27,54 @@ % -------------------- % top : double % number of enzymes to return (default 10). +% foldChange : double +% a value how much to increase the usage upper bound of an enzyme that +% runs at its upper bound; must be greater than 1 (default 2). % % Returns % ------- % bottlenecks : table -% one row per returned enzyme, sorted by descending absolute shadow -% price, with columns uniprot, gene, shadowPrice, flux, capUsage -% (abs(flux)/upperBound, NaN if upperBound is 0) and upperBound. +% one row per returned enzyme, sorted by descending objectiveGain, with +% columns uniprot, gene, objectiveGain (objective after raising the +% bound minus the objective of the unchanged model; 0 for enzymes not at +% their upper bound, for gains below 1e-10 and for solves that are not +% optimal), shadowPrice, flux, capUsage (abs(flux)/upperBound, NaN if +% upperBound is 0), upperBound and multipleActive. An enzyme is at its +% upper bound when upperBound is above 0 and capUsage is at least +% 1 - 1e-6. multipleActive is true when at least one other constraint +% is active: another enzyme at its upper bound, or prot_pool_exchange at +% its upper bound (within 1e-6 relative). Where it is true, the dual is +% not informative about a single enzyme. The table property +% UserData.nResolved holds the number of enzymes that were solved again +% and UserData.activeConstraints the number of active constraints. +% When no enzyme is at its usage bound a warning (getEnzymeBottlenecks:noEnzymeAtBound) +% says that no single enzyme limits the objective; every objectiveGain is then 0 and +% the rows are in model order. % % Examples % -------- % bottlenecks = getEnzymeBottlenecks(ecModel); -% bottlenecks = getEnzymeBottlenecks(ecModel, 'top', 5); +% bottlenecks = getEnzymeBottlenecks(ecModel, 'top', 5, 'foldChange', 3); -p = parseGECKOargs(varargin, {'top', []}); +p = parseGECKOargs(varargin, {'top', []; 'foldChange', []}); top = p.top; +foldChange = p.foldChange; if isempty(top) top = 10; end +if isempty(foldChange) + foldChange = 2; +end +if ~isnumeric(foldChange) || ~isscalar(foldChange) || ~(foldChange > 1) + error('getEnzymeBottlenecks:foldChange', 'foldChange must be greater than 1') +end if isfield(model.ec, 'geckoLight') && model.ec.geckoLight error(['getEnzymeBottlenecks requires a full ecModel, not gecko-light: ' ... 'light models have no per-enzyme prot_ / usage_prot_ machinery.']) end -sol = solveLP(model); +[sol, hs] = solveLP(model); if sol.stat ~= 1 error('getEnzymeBottlenecks: solver status %d; cannot rank bottlenecks.', sol.stat) end @@ -65,8 +99,46 @@ capUsage = abs(flux) ./ upperBound; capUsage(upperBound == 0) = NaN; -bottlenecks = table(uniprot, gene, shadowPrice, flux, capUsage, upperBound); -[~, order] = sort(abs(bottlenecks.shadowPrice), 'descend'); +nEnz = numel(uniprot); +atCap = upperBound > 0 & capUsage >= 1 - 1e-6; +base = sol.f; +objectiveGain = zeros(nEnz, 1); +for i = find(atCap)' + tempModel = model; + tempModel.ub(rxnIdx(i)) = upperBound(i) * foldChange; + [tempSol, hs] = solveLP(tempModel, 0, [], hs); + if tempSol.stat == 1 + gain = tempSol.f - base; + if gain >= 1e-10 + objectiveGain(i) = gain; + end + end +end + +activeConstraints = nnz(atCap); +poolActive = false; +poolIdx = find(strcmp(model.rxns, 'prot_pool_exchange'), 1); +if ~isempty(poolIdx) && isfinite(model.ub(poolIdx)) && model.ub(poolIdx) > 0 ... + && abs(sol.x(poolIdx)) >= model.ub(poolIdx) * (1 - 1e-6) + activeConstraints = activeConstraints + 1; + poolActive = true; +end +if ~any(atCap) + if poolActive + state = 'the protein pool exchange is at its bound'; + else + state = 'no capacity constraint is active'; + end + warning('getEnzymeBottlenecks:noEnzymeAtBound', ... + ['getEnzymeBottlenecks: no enzyme is at its usage bound, so no single enzyme limits ' ... + 'the objective; %s. Every objectiveGain is 0 and the rows are in model order.'], state) +end +multipleActive = (activeConstraints - double(atCap)) >= 1; + +bottlenecks = table(uniprot, gene, objectiveGain, shadowPrice, flux, capUsage, upperBound, multipleActive); +[~, order] = sortrows([-round(objectiveGain, 9), (1:nEnz)']); bottlenecks = bottlenecks(order, :); bottlenecks = bottlenecks(1:min(top, height(bottlenecks)), :); +bottlenecks.Properties.UserData.nResolved = nnz(atCap); +bottlenecks.Properties.UserData.activeConstraints = activeConstraints; end diff --git a/src/enzyme_usage/getEnzymeUsage.m b/src/enzyme_usage/getEnzymeUsage.m index 32bd52be..ac09a085 100644 --- a/src/enzyme_usage/getEnzymeUsage.m +++ b/src/enzyme_usage/getEnzymeUsage.m @@ -39,7 +39,9 @@ % - capUsage : vector of enzyme capacity usages. % - absUsage : vector of absolute enzyme usages. % - UB : vector of enzyme exchange reaction upper bounds. -% - protID : string array of matching protein IDs. +% - protID : string array of matching protein IDs. An enzyme without a +% usage_prot_ reaction in the model is left out, with the warning +% getEnzymeUsage:missingUsageReaction. % - fluxes : vector of fluxes, copy of input fluxes. % % Examples @@ -60,6 +62,14 @@ end usageData.protID = ecModel.ec.enzymes; [~,rxnIdx] = ismember(strcat('usage_prot_',ecModel.ec.enzymes),ecModel.rxns); +noUsageRxn = rxnIdx == 0; +if any(noUsageRxn) + warning('getEnzymeUsage:missingUsageReaction', ... + 'The model has no usage reaction for the enzymes %s; they are left out.', ... + strjoin(usageData.protID(noUsageRxn), ', ')) + usageData.protID = usageData.protID(~noUsageRxn); + rxnIdx = rxnIdx(~noUsageRxn); +end usageData.UB = ecModel.ub(rxnIdx); usageData.absUsage = abs(fluxes(rxnIdx)); diff --git a/src/enzyme_usage/reportEnzymeUsage.m b/src/enzyme_usage/reportEnzymeUsage.m index 72cb88e5..ff313280 100644 --- a/src/enzyme_usage/reportEnzymeUsage.m +++ b/src/enzyme_usage/reportEnzymeUsage.m @@ -20,7 +20,7 @@ % how many top enzymes by absolute usage to list (default 10). Use 0 % or Inf to list all enzymes instead. Enzymes whose reactions carry no % flux are never listed here, as they do not contribute to the -% solution. +% solution. A negative value raises reportEnzymeUsage:invalidTopAbsUsage. % % Returns % ------- @@ -54,6 +54,9 @@ % values it used to reach the indexing below unclamped: usageData.protID(topUse(1:N)) % with N > numel(topUse) is an out-of-bounds index, so any model with fewer than 10 % enzymes (ecTestGEM has 5) crashed on the default call. +if ~(isnumeric(topAbsUsage) && isscalar(topAbsUsage) && topAbsUsage >= 0) + error('reportEnzymeUsage:invalidTopAbsUsage', 'topAbsUsage must be a non-negative number.') +end if topAbsUsage == 0 || isinf(topAbsUsage) || topAbsUsage > numel(usageData.protID) topAbsUsage = numel(usageData.protID); end @@ -84,8 +87,8 @@ if isscalar(find(carriedFlux)) highUsage.protID(end+1,1) = highEnzyme(i); highUsage.geneID(end+1,1) = geneIDs(i); - highUsage.absUsage(end+1,1) = usageData.absUsage(enzIdx(i)); - highUsage.capUsage(end+1,1) = usageData.capUsage(enzIdx(i)); + highUsage.absUsage(end+1,1) = usageData.absUsage(highUsageProt(i)); + highUsage.capUsage(end+1,1) = usageData.capUsage(highUsageProt(i)); highUsage.kcat(end+1,1) = kcat(carriedFlux); highUsage.source(end+1,1) = ecModel.ec.source(idx(carriedFlux)); highUsage.rxnID(end+1,1) = rxns(carriedFlux); @@ -95,8 +98,8 @@ % Add one entry for combined usage highUsage.protID(end+1,1) = highEnzyme(i); highUsage.geneID(end+1,1) = geneIDs(i); - highUsage.absUsage(end+1,1) = usageData.absUsage(enzIdx(i)); - highUsage.capUsage(end+1,1) = usageData.capUsage(enzIdx(i)); + highUsage.absUsage(end+1,1) = usageData.absUsage(highUsageProt(i)); + highUsage.capUsage(end+1,1) = usageData.capUsage(highUsageProt(i)); highUsage.kcat(end+1,1) = nan; highUsage.source{end+1,1} = '==='; highUsage.rxnID{end+1,1} = '==='; @@ -109,7 +112,7 @@ enzMet = strcat('prot_',highEnzyme{i}); [~, enzEcIdx] = ismember(enzMet,ecModel.mets); indAbsUse = full(transpose(-ecModel.S(enzEcIdx,rIdx)).*enzFlux); - indCapUse = (indAbsUse /sum(indAbsUse)) * usageData.capUsage(enzIdx(i)); + indCapUse = (indAbsUse /sum(indAbsUse)) * usageData.capUsage(highUsageProt(i)); rxnNumber = length(rIdx); highUsage.protID(end+1:end+rxnNumber,1) = highEnzyme(i); diff --git a/src/flux_analysis/ecFSEOF.m b/src/flux_analysis/ecFSEOF.m index 0ec57b93..f5801526 100644 --- a/src/flux_analysis/ecFSEOF.m +++ b/src/flux_analysis/ecFSEOF.m @@ -3,7 +3,9 @@ % % Runs Flux-Scanning with Enforced Objective Function (FSEOF) for a % specified production target, to identify reaction and gene targets for -% metabolic engineering. +% metabolic engineering. Reactions are classified as targets with the same +% rule as RAVEN's FSEOF: the correlation between the absolute flux of a +% reaction and the enforced production flux. % % Parameters % ---------- @@ -28,6 +30,10 @@ % modelAdapter, e.g. output/ecFSEOF_rxns.tsv). % modelAdapter : ModelAdapter % a loaded model adapter (default: the current default model adapter). +% corrThreshold : double +% minimum absolute Pearson correlation between the absolute flux of a +% reaction and the enforced production flux for the reaction to be a +% target (default 0.9). % % Returns % ------- @@ -40,25 +46,36 @@ % % - alpha : target production used for enforced objective limits (from minimum to maximum production). % - v_matrix : fluxes for each target reaction predicted and each alpha. -% - rxnTargets : a list with all reactions with fluxes that change consistently as target production increases. Contains ID, name, slope, gene rule, and equation. -% - transportTargets : a list with all transport reactions with fluxes that change consistently as target production increases. Contains ID, name, slope, gene rule, and equation. -% - geneTargets : a list with all selected targets that increase production. Contains gene, shortName, slope, action, and essentiality. +% - rxnTargets : a list with all reactions whose absolute flux is correlated with the enforced production, with an absolute correlation of at least corrThreshold. Contains ID, name, slope, gene rule, and equation. The slope is the absolute slope of the regression of the absolute flux on the enforced production flux. The list is ordered by the product of slope and correlation, highest first. +% - transportTargets : the same for transport reactions. +% - geneTargets : a list with all genes of the targets. Contains gene, shortName, slope, action, and essentiality. +% +% Only reactions with a gene rule are considered, and not those that are +% assigned to the standard enzyme. The enforced production reaction is +% included when it has a gene rule, as its flux follows the enforced +% production by definition. The reactions that draw enzyme usage +% (usage_prot_*) take part in the classification and are not reported. +% A reaction is over expressed (OE) when its flux increases with production, +% knocked out (KO) when it decreases and is at most 1e-8 at the last step, +% and knocked down (KD) when it decreases otherwise. % % Examples % -------- % % optional arguments may be given positionally or as name-value pairs: -% fseof = ecFSEOF(model,prodTargetRxn,csRxn,nSteps,outputFile,filePath,modelAdapter); +% fseof = ecFSEOF(model,prodTargetRxn,csRxn,nSteps,outputFile,filePath,modelAdapter,corrThreshold); % fseof = ecFSEOF(model,prodTargetRxn,csRxn,'nSteps',32); p = parseGECKOargs(varargin, { ... 'nSteps', 16; ... 'outputFile', false; ... 'filePath', []; ... - 'modelAdapter', []}); + 'modelAdapter', []; ... + 'corrThreshold',0.9}); nSteps = p.nSteps; outputFile = p.outputFile; filePath = p.filePath; -modelAdapter = p.modelAdapter; +modelAdapter = p.modelAdapter; +corrThreshold = p.corrThreshold; if isempty(modelAdapter) modelAdapter = ModelAdapterManager.getDefault(); @@ -133,65 +150,68 @@ v_matrix = v_matrix(withGR,:); rxnGeneM = model.rxnGeneMat(withGR,:); -% Filter out rxns that are always zero -zero_flux = ~all(abs(v_matrix(:,1:nSteps))==0,2); -target_rxns = target_rxns(zero_flux,:); -v_matrix = v_matrix(zero_flux,:); -rxnGeneM = rxnGeneM(zero_flux,:); - -% Identify those rxns that always increase or decrease, and calculate the -% slope as the difference in the flux when enforce objetive target -% production is set to 90%% of the maximum teorethical yield -% << v_matrix(i,nSteps-1) >> and the flux when the enforce objetive target -% production is set to the minimum << v_matrix(i,1) >> for the reaction i, -% divided by maxTarget-maxTarget/nSteps-1. +% Classify the reactions as in RAVEN's FSEOF. Slope and correlation are taken +% on the absolute flux against the enforced production flux, so a reversible +% reaction running backwards counts by its magnitude. A reaction is a target +% when some absolute flux exceeds 1e-10, the standard deviation of its +% absolute flux is above 0 and the absolute Pearson correlation reaches +% corrThreshold. It is suggested for over expression (OE) when the slope is +% positive, for knock out (KO) when the slope is negative and the absolute +% flux at the last step is at most 1e-8, and for knock down (KD) for any +% other negative slope. +absV = abs(v_matrix); slope_rxns = zeros(size(target_rxns)); -targets = logical(size(target_rxns)); +corr_rxns = zeros(size(target_rxns)); target_type = cell(size(target_rxns)); -for i = 1:length(target_rxns) - if issorted(abs(v_matrix(i,1:nSteps)),'strictascend') - % Those reactions that always increase while enforcing target - % production are suggested for Over Expression - targets(i) = true; - slope_rxns(i) = abs(v_matrix(i,nSteps-1)-v_matrix(i,1))/abs(maxTarget-maxTarget/nSteps-1); - target_type(i) = {'OE'}; - elseif issorted(abs(v_matrix(i,1:nSteps)),'strictdescend') - % Those reactions that always decrease while enforcing target - % production are suggested for KnockDown or KnockOut. KO are those - % reactions which have zero flux when enforcing target production - % to 90%% of the maximum theoretical yield. - targets(i) = true; - slope_rxns(i) = abs(v_matrix(i,nSteps-1)-v_matrix(i,1))/abs(maxTarget-maxTarget/nSteps-1); - if v_matrix(i,nSteps) == 0 - target_type(i) = {'KO'}; - else - target_type(i) = {'KD'}; +targets = false(size(target_rxns)); +if numel(alpha) > 1 && std(alpha) > 0 + for i = 1:length(target_rxns) + track = absV(i,:); + if any(track > 1e-10) && std(track) > 0 + fit = polyfit(alpha,track,1); + r = corrcoef(alpha,track); + if abs(r(1,2)) >= corrThreshold && fit(1) ~= 0 + targets(i) = true; + slope_rxns(i) = abs(fit(1)); + corr_rxns(i) = abs(r(1,2)); + if fit(1) > 0 + target_type(i) = {'OE'}; + elseif track(end) <= 1e-8 + target_type(i) = {'KO'}; + else + target_type(i) = {'KD'}; + end + end end end end -% Only keep those reaction that shows an increase or decrease pattern. +% Only keep those reactions that are classified as a target target_rxns = target_rxns(targets); v_matrix = v_matrix(targets,:); rxnGeneM = rxnGeneM(targets,:); slope_rxns = slope_rxns(targets); +corr_rxns = corr_rxns(targets); target_type = target_type(targets); -% Order from highest to lowest slope -[~,order] = sort(slope_rxns,'descend'); +% Order from highest to lowest score, the product of slope and correlation, +% rounded to 9 significant digits so that scores equal up to solver noise keep +% the order of the model +[~,order] = sort(round(slope_rxns .* corr_rxns,9,'significant'),'descend'); target_rxns = target_rxns(order); v_matrix = v_matrix(order,:); rxnGeneM = rxnGeneM(order,:); slope_rxns = slope_rxns(order); target_type = target_type(order); -% Filter out reactions with slope < quantile -non_zero_slope = slope_rxns > quantile(slope_rxns,0.75); -target_rxns = target_rxns(non_zero_slope); -v_matrix = v_matrix(non_zero_slope,:); -rxnGeneM = rxnGeneM(non_zero_slope,:); -slope_rxns = slope_rxns(non_zero_slope); -target_type = target_type(non_zero_slope); +% Exclude enzyme usage reactions: they are not reported, and they would otherwise +% enter the gene slopes and the choice of the action per gene +notUsage = ~startsWith(target_rxns,'usage_prot_'); +target_rxns = target_rxns(notUsage); +v_matrix = v_matrix(notUsage,:); +rxnGeneM = rxnGeneM(notUsage,:); +slope_rxns = slope_rxns(notUsage); +target_type = target_type(notUsage); % Create gene list of those connected to the remaining rxns genes = model.genes(sum(rxnGeneM,1) > 0); @@ -255,20 +275,22 @@ % Report values used to enforce objective target production fseof.alpha = alpha; -% Exclude enzyme usage reactions -toKeep = ~startsWith(target_rxns,'usage_prot_'); -rxnIdx = getIndexes(model,target_rxns(toKeep),'rxns'); +rxnIdx = getIndexes(model,target_rxns,'rxns'); % Report the fluxes at each alpha -fseof.v_matrix = array2table(v_matrix(toKeep,:), ... +fseof.v_matrix = array2table(v_matrix, ... 'VariableNames', string(alpha), 'RowNames', model.rxns(rxnIdx)); % Report reaction targets fseof.rxnTargets(:,1) = model.rxns(rxnIdx); fseof.rxnTargets(:,2) = model.rxnNames(rxnIdx); -fseof.rxnTargets(:,3) = num2cell(slope_rxns(toKeep)); +fseof.rxnTargets(:,3) = num2cell(slope_rxns); fseof.rxnTargets(:,4) = model.grRules(rxnIdx); -fseof.rxnTargets(:,5) = constructEquations(model,rxnIdx); +if isempty(rxnIdx) + fseof.rxnTargets(:,5) = cell(0,1); % constructEquations would give all reactions +else + fseof.rxnTargets(:,5) = constructEquations(model,rxnIdx); +end % Identify transport reactions; defined as reactions involving (at least) % one metabolite name in more than one compartment. diff --git a/src/flux_analysis/ecFVA.m b/src/flux_analysis/ecFVA.m index dfee0ca4..e4aee30a 100644 --- a/src/flux_analysis/ecFVA.m +++ b/src/flux_analysis/ecFVA.m @@ -42,7 +42,7 @@ 'runParallel', true}); runParallel = p.runParallel; -rxnIDs = regexprep(ecModel.rxns,'(_REV)?(_EXP_\d+)?',''); +rxnIDs = regexprep(ecModel.rxns,'(_REV)?(_EXP_\d+)?$',''); [rxnIDmap, convRxnID] = findgroups(rxnIDs); N = numel(convRxnID); diff --git a/src/flux_analysis/getPfbaEnzymes.m b/src/flux_analysis/getPfbaEnzymes.m index 625eddd8..d14bc34e 100644 --- a/src/flux_analysis/getPfbaEnzymes.m +++ b/src/flux_analysis/getPfbaEnzymes.m @@ -21,7 +21,10 @@ % (default: use model.c as given). % fractionOfOptimum : double % fraction of the optimal objective value to fix before minimising -% enzyme usage (default 1.0). +% enzyme usage (default 1.0). A value below 1.0 lets the objective fall +% by (1 - fractionOfOptimum) times the magnitude of its optimum, so it +% also applies to a negative optimum (for example the exchange flux of +% a nutrient that is maximised). % % Returns % ------- @@ -89,12 +92,10 @@ % Fix the objective as a constraint, same "fake metabolite" technique % solveLP's own minFlux=1 option uses (see solveLP.m). -target = fractionOfOptimum * solOrig.f; -if target > 0 - target = target * 0.999999; -else - target = target * 1.000001; -end +% The objective may fall by (1 - fractionOfOptimum*0.999999) of the magnitude +% of its optimum, for a positive and a negative optimum alike (the band that +% setParam(model, 'var', ...) sets around a value). +target = solOrig.f - (1 - fractionOfOptimum*0.999999) * abs(solOrig.f); fixModel = model; fixModel.S(end+1, :) = model.c'; fixModel.mets{end+1, 1} = 'getPfbaEnzymes_objective'; diff --git a/src/gather_kcats/assignKcatValues.m b/src/gather_kcats/assignKcatValues.m index c7ec1c14..227ca798 100644 --- a/src/gather_kcats/assignKcatValues.m +++ b/src/gather_kcats/assignKcatValues.m @@ -21,6 +21,8 @@ % - genes : gene identifiers, matching model.ec.genes. % - substrates : substrate names, matching model.metNames. % - kcats : predicted kcat value in /sec. +% - kcatSource : optional, the source of each entry; entries with a zero +% kcat are discarded together with their source. % % Name-Value Arguments % -------------------- @@ -31,6 +33,11 @@ % 'median'/'mean', where the selected value need not equal any single % input, it is taken from the first entry instead (arbitrary but % deterministic, since an aggregate has no single "winning" source). +% The source is written in lower case snake_case, with the wildcard +% level and origin of the entry in brackets when it has them +% (kcatList.wildcardLvl and kcatList.origin), for example +% 'brenda (wc=0, origin=1)'. Functions that compare model.ec.source with +% a source name use the part before ' (' (see resolveTunableContext). % overwrite : char % whether existing kcat values should be overwritten. Options: 'true', % 'false', 'ifHigher'. The last option will overwrite only if the new @@ -75,8 +82,22 @@ % Remove zero kcat values. Only adjusting fields that are used later. removeZero = kcatList.kcats == 0; +nEntries = numel(removeZero); +wildcardLvl = nan(nEntries, 1); +origin = nan(nEntries, 1); +if isfield(kcatList,'wildcardLvl') && numel(kcatList.wildcardLvl) == nEntries + wildcardLvl = double(kcatList.wildcardLvl(:)); +end +if isfield(kcatList,'origin') && numel(kcatList.origin) == nEntries + origin = double(kcatList.origin(:)); +end +wildcardLvl(removeZero) = []; +origin(removeZero) = []; kcatList.kcats(removeZero) = []; kcatList.rxns(removeZero) = []; +if isfield(kcatList,'kcatSource') + kcatList.kcatSource(removeZero) = []; +end % Map to model.ec.rxns [sanityCheck,idxInModel] = ismember(kcatList.rxns,model.ec.rxns); @@ -109,7 +130,8 @@ otherwise error('Invalid criteria specified') end - selectedSource(i) = kcatList.kcatSource(idxMatch(j)); + selectedSource{i} = formatKcatSource(kcatList.kcatSource{idxMatch(j)}, ... + wildcardLvl(idxMatch(j)), origin(idxMatch(j))); end % Populate model.ec.kcat @@ -135,3 +157,17 @@ end rxnIdx = idxInModelUnique; end + +function text = formatKcatSource(source, wildcardLvl, origin) +% The provenance text of model.ec.source: the source label in lower case +% snake_case, followed by the wildcard level and origin of a fuzzy BRENDA +% match in brackets, e.g. 'brenda (wc=0, origin=1)'. +text = lower(strtrim(char(source))); +text = regexprep(text, '[^0-9a-z]+', '_'); +text = regexprep(text, '^_+|_+$', ''); +if ~isnan(wildcardLvl) && ~isnan(origin) + text = sprintf('%s (wc=%d, origin=%d)', text, fix(wildcardLvl), fix(origin)); +elseif ~isnan(wildcardLvl) + text = sprintf('%s (wc=%d)', text, fix(wildcardLvl)); +end +end diff --git a/src/gather_kcats/assignKcats.m b/src/gather_kcats/assignKcats.m new file mode 100644 index 00000000..25554ef3 --- /dev/null +++ b/src/gather_kcats/assignKcats.m @@ -0,0 +1,57 @@ +function [model, decisions, report] = assignKcats(model, varargin) +% assignKcats Assign kcats from the kcat source files and apply them. +% +% Decides one kcat per reaction from the kcat source files in data/kcats, +% as [kcat_assignment] in model_adapter.toml sets (see collectKcats), writes +% model.ec.kcat and model.ec.source, and applies the kcat constraints +% (applyKcatConstraints). Any kcats the model had are replaced: the source +% files are the input, and nothing in the model is written back to them. +% +% Parameters +% ---------- +% model : struct +% an ecModel in GECKO 3 format (with ecModel.ec structure). +% +% Name-Value Arguments +% -------------------- +% modelAdapter : ModelAdapter +% a loaded model adapter (default: the current default model adapter). +% writeReport : logical +% write the decisions to output/_kcatDecisions.tsv (default +% true). +% +% Returns +% ------- +% model : struct +% the ecModel with the assigned kcats applied. +% decisions, report +% as returned by collectKcats. +% +% Examples +% -------- +% updateKcatSources(ecModel); % gather what the configuration needs +% ecModel = assignKcats(ecModel); +% +% See also +% -------- +% collectKcats, updateKcatSources, applyKcatConstraints + +checkOptions(varargin, {'modelAdapter','writeReport'}, 'assignKcats'); +[decisions, report, model] = collectKcats(model, varargin{:}); +model = applyKcatConstraints(model); +end + +function checkOptions(args, names, functionName) +% Options are name-value pairs with known names, so a misspelled option is +% an error instead of being taken as a positional argument. +id = [functionName ':arguments']; +given = args(1:2:end); +if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given)) + error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', ')) +end +unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names); +if ~isempty(unknown) + error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ... + strjoin(names, ', ')) +end +end diff --git a/src/gather_kcats/collectKcats.m b/src/gather_kcats/collectKcats.m new file mode 100644 index 00000000..2bf88084 --- /dev/null +++ b/src/gather_kcats/collectKcats.m @@ -0,0 +1,467 @@ +function [decisions, report, ecModel] = collectKcats(model, varargin) +% collectKcats Decide one kcat per reaction from the kcat source files. +% +% Combines the kcat source files in data/kcats (see kcatsFromBrenda, +% kcatsFromDLKcat, kcatsFromOKP and saveKcatSource) as [kcat_assignment] in +% model_adapter.toml sets, without changing the model given. assignKcats +% applies the decisions. +% +% The order is a preset or a list of stages: +% +% [kcat_assignment] +% preset = "brenda_ec_tree" # the default; or ec_tree_homologs, ec_tree_okp, okp, +% # gecko_median, gecko_classic +% isozymes = true # fill from isozymes after the stages +% standard = true # standard kcat for the rest +% +% # instead of a preset: +% [[kcat_assignment.stage]] +% action = "select" # or "combine" +% sources = ["custom", "database_top", "ec_tree"] +% criteria = "max" # select: among several values of one source +% top_origin_limit = 1 +% +% [kcat_sources.okp] +% methods = ["CataPro", "UniKP"] # the okp source group +% +% A stage decides the reactions that are still open: +% - select: the first listed source with a value (see mergeKcats). Sources +% are the names of source files (custom, ec_tree, dlkcat, okp_catapro, +% ...) and the BRENDA quality tiers database_exact, database_top and +% database_bottom, which read brenda.tsv. +% - combine: all listed sources with a value, each corrected for its bias +% and weighted by 1 / its error variance, both for the source's evidence +% for that reaction (the EC tree: measurements of the EC and its EC +% level; an OKP method: the enzyme's similarity to the method's training +% sequences). The parameters come with the BRENDA files +% (kcatCombineParams.tsv). model.ec.source reads 'combined (sd=, n=)'; sd is the uncertainty for a new measurement. +% In both, okp stands for the OKP methods of [kcat_sources.okp] methods +% (default: all methods with combination parameters). +% +% The presets: +% - brenda_ec_tree (the default): custom kcats, the BRENDA median of +% measurements of the organism on the reaction's substrate (origin 1, +% without EC wildcards), the EC tree (kcatsFromECTree); then the OKP +% methods combined for the reactions left (without an EC number). +% - ec_tree_homologs: custom kcats, the organism's own BRENDA value; then +% the EC tree and homologs (kcatsFromHomologs) combined; then the OKP +% methods combined. +% - ec_tree_okp: custom kcats, the organism's own BRENDA value; then the EC +% tree, homologs and the OKP methods combined; then the OKP methods +% combined. +% - okp: custom kcats; then the OKP methods combined. +% - gecko_median: custom kcats, the BRENDA median of matches without EC +% wildcards from the organism or other organisms, with or without the +% substrate (origin 1 to 4), DLKcat, then the other BRENDA matches (EC +% wildcards, and specific activities, origin 5 and 6). +% - gecko_classic: as gecko_median with the BRENDA maximum and the +% specific-activity matches above DLKcat (origin up to 6), as the GECKO 3 +% tutorial. +% Against measured kcats hidden from the search, the EC tree was closer +% than the BRENDA median at origins 2 and 4 and with EC wildcards and as +% close at origins 1 and 3; the EC tree combined with the OKP methods was +% slightly closer than the EC tree, and the OKP methods combined as close. +% In ecModels, values combined with predictions set high-turnover enzymes +% such as ATP synthase too low, which is why the default uses predictions +% only where there is no value from measurements. The BRENDA aggregation is +% [kcat_sources.brenda] aggregation (see updateKcatSources). +% +% After the stages: +% - custom kcats of data/customKcats.tsv are applied (applyCustomKcats), +% when a stage lists custom but there is no data/kcats/custom.tsv; +% - with isozymes, reactions without a kcat take one from their isozymes +% (getKcatAcrossIsozymes); +% - with standard, the remaining reactions get the standard kcat +% (getStandardKcat). +% +% A source file a stage names that does not exist is reported and left out. +% +% Parameters +% ---------- +% model : struct +% an ecModel in GECKO 3 format (with ecModel.ec structure). +% +% Name-Value Arguments +% -------------------- +% modelAdapter : ModelAdapter +% a loaded model adapter (default: the current default model adapter). +% writeReport : logical +% write the decisions to output/_kcatDecisions.tsv (default +% true). +% +% Returns +% ------- +% decisions : table +% one row per model.ec reaction: ecRxn, stage (the stage number, or +% custom, isozymes, standard, or empty when no kcat was found), source +% (as in model.ec.source), kcat, candidates (the number of values the +% deciding source had for the reaction, or of sources combined), +% spreadLog10 (their range, in log10 units) and sdLog10 (the +% uncertainty of a combined value). +% report : struct +% - preset: the preset used, or '' with stages; +% - missing: source files the stages name that do not exist; +% - sources: per source file loaded, its unmatched, partial and invalid +% rows (see loadKcatSource). +% ecModel : struct +% the model with the decided kcats, before applyKcatConstraints; this +% is what assignKcats returns, after applying the constraints. +% +% Examples +% -------- +% decisions = collectKcats(ecModel); +% decisions(strcmp(decisions.stage, ''), :) % reactions without a kcat +% +% See also +% -------- +% assignKcats, updateKcatSources, loadKcatSource, mergeKcats, assignKcatValues + +checkOptions(varargin, {'modelAdapter','writeReport'}, 'collectKcats'); +p = parseGECKOargs(varargin, {'modelAdapter', []; 'writeReport', true}); +modelAdapter = p.modelAdapter; +if isempty(modelAdapter) + modelAdapter = ModelAdapterManager.getDefault(); + if isempty(modelAdapter) + error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.') + end +end +params = modelAdapter.params; +config = kcatAssignmentConfig(params); +kcatDir = fullfile(params.path, 'data', 'kcats'); + +ecModel = model; +nEc = numel(ecModel.ec.rxns); +ecModel.ec.kcat(:) = 0; +ecModel.ec.source(:) = {''}; +stage = repmat({''}, nEc, 1); +candidates = zeros(nEc, 1); +spread = nan(nEc, 1); +sd = nan(nEc, 1); +combineParams = []; + +report.preset = config.preset; +report.missing = {}; +report.sources = struct(); +loaded = struct(); +legacyCustom = false; + + function list = loadSource(name) + % The kcat list of a source file, or [] when it does not exist. + list = []; + file = fullfile(kcatDir, [name '.tsv']); + if isfile(file) + [list, rep] = loadKcatSource(ecModel, file); + report.sources.(name) = rep; + elseif strcmp(name, 'custom') && isfile(fullfile(params.path, 'data', 'customKcats.tsv')) + legacyCustom = true; + else + report.missing{end+1} = name; + printOrange(sprintf(['No kcat source file %s; it is left out. ' ... + 'updateKcatSources gathers it.\n'], file)); + end + end + +for s = 1:numel(config.stages) + st = config.stages(s); + if strcmp(st.action, 'combine') + names = {}; + lists = {}; + for t = 1:numel(st.files) + name = st.files{t}; + if ~isfield(loaded, name) + loaded.(name) = loadSource(name); + end + if ~isempty(loaded.(name)) + names{end+1} = name; %#ok + lists{end+1} = loaded.(name); %#ok + end + end + if isempty(names) + continue + end + if isempty(combineParams) + combineParams = loadCombineParams(modelAdapter); + end + openRxns = ecModel.ec.rxns(ecModel.ec.kcat == 0); + c = combineKcats(names, lists, openRxns, combineParams); + if isempty(c.rxns) + continue + end + [~, idx] = ismember(c.rxns, ecModel.ec.rxns); + ecModel.ec.kcat(idx) = c.kcats; + ecModel.ec.source(idx) = cellstr(compose('combined (sd=%.2f, n=%d)', c.sd, c.n)); + stage(idx) = {sprintf('%d', s)}; + candidates(idx) = c.n; + spread(idx) = c.spread; + sd(idx) = c.sd; + continue + end + lists = {}; + usedFiles = {}; + priority = {}; + for t = 1:numel(st.files) + token = st.files{t}; + name = sourceFile(token); + if ~isfield(loaded, name) + loaded.(name) = loadSource(name); + end + list = loaded.(name); + if isempty(list) + continue + end + if ~ismember(name, usedFiles) + lists{end+1} = list; %#ok + usedFiles{end+1} = name; %#ok + end + if startsWith(token, 'database_') + priority{end+1} = token; %#ok + else + % The labels of the file's rows, at the file's place in the order. + labels = unique(cellfun(@normalizeSource, list.kcatSource, 'UniformOutput', false), 'stable'); + priority = [priority, labels(~ismember(labels, {'brenda','sabio_rk'}))']; %#ok + end + end + if isempty(lists) || isempty(priority) + continue + end + merged = mergeKcats(lists, priority, 'topOriginLimit', st.topOriginLimit, ... + 'bottomOriginLimit', st.bottomOriginLimit, 'wildcardLimit', st.wildcardLimit); + if isempty(merged.rxns) + continue + end + open = ecModel.ec.kcat == 0; + [ecModel, idx] = assignKcatValues(ecModel, merged, 'criteria', st.criteria, 'overwrite', 'false'); + idx = idx(open(idx)); + stage(idx) = {sprintf('%d', s)}; + [~, where] = ismember(merged.rxns, ecModel.ec.rxns); + valid = merged.kcats > 0; + for i = idx(:)' + values = merged.kcats(where == i & valid); + candidates(i) = numel(values); + spread(i) = log10(max(values)) - log10(min(values)); + end +end + +if legacyCustom + before = ecModel.ec.kcat; + ecModel = applyCustomKcats(ecModel, 'modelAdapter', modelAdapter); + changed = ecModel.ec.kcat ~= before; + stage(changed) = {'custom'}; + candidates(changed) = 1; + spread(changed) = 0; +end +if config.isozymes && ~ecModel.ec.geckoLight + before = ecModel.ec.kcat == 0; + ecModel = getKcatAcrossIsozymes(ecModel); + stage(before & ecModel.ec.kcat > 0) = {'isozymes'}; +end +if config.standard + ecModel = getStandardKcat(ecModel, 'modelAdapter', modelAdapter); + n = numel(ecModel.ec.rxns); + stage(end+1:n) = {''}; + candidates(end+1:n) = 0; + spread(end+1:n) = NaN; + sd(end+1:n) = NaN; + stage(strcmp(ecModel.ec.source, 'standard') & ecModel.ec.kcat > 0) = {'standard'}; +end + +decisions = table(ecModel.ec.rxns(:), stage(:), ecModel.ec.source(:), ecModel.ec.kcat(:), ... + candidates(:), spread(:), sd(:), 'VariableNames', {'ecRxn','stage','source','kcat','candidates', ... + 'spreadLog10','sdLog10'}); +if p.writeReport + outDir = fullfile(params.path, 'output'); + if ~isfolder(outDir) + mkdir(outDir); + end + id = 'ecModel'; + if isfield(model, 'id') && ~isempty(model.id) + id = char(model.id); + end + writetable(decisions, fullfile(outDir, [id '_kcatDecisions.tsv']), 'FileType', 'text', ... + 'Delimiter', '\t'); +end +nOpen = sum(strcmp(stage, '')); +fprintf('Kcats decided for %d of %d reactions.\n', numel(stage) - nOpen, numel(stage)); +end + +function s = normalizeSource(label) +% As mergeKcats folds source labels: lower case, other characters as '_', +% without a leading okp_ (the tag of OpenKineticsPredictor rows). +s = lower(strtrim(char(label))); +s = regexprep(s, '[^0-9a-z]+', '_'); +s = regexprep(s, '^_+|_+$', ''); +s = regexprep(s, '^okp_', ''); +end + +function name = sourceFile(token) +% The source file a stage token reads: the BRENDA tiers read brenda.tsv. +if startsWith(token, 'database_') + name = 'brenda'; +else + name = token; +end +end + +function checkOptions(args, names, functionName) +% Options are name-value pairs with known names, so a misspelled option is +% an error instead of being taken as a positional argument. +id = [functionName ':arguments']; +given = args(1:2:end); +if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given)) + error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', ')) +end +unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names); +if ~isempty(unknown) + error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ... + strjoin(names, ', ')) +end +end + +function params = loadCombineParams(modelAdapter) +% kcatCombineParams.tsv of the BRENDA folder, or of GECKO's BRENDA release. +file = fullfile(modelAdapter.getBrendaDBFolder(), 'kcatCombineParams.tsv'); +if ~isfile(file) + file = fullfile(fetchBrendaAsset({'kcatCombineParams.tsv'}), 'kcatCombineParams.tsv'); +end +lines = strsplit(fileread(file), {'\r\n', '\n'}); +params.measurementSd = 0.48; +params.minVariance = 0.01; +params.scaleKeys = {}; +params.scales = []; +k = 1; +while k <= numel(lines) && startsWith(lines{k}, '#') + tok = regexp(lines{k}, '^#\s*([^:]+):\s*(.*)$', 'tokens', 'once'); + if ~isempty(tok) + key = strtrim(tok{1}); + value = str2double(strtrim(tok{2})); + if strcmp(key, 'measurement_sd') + params.measurementSd = value; + elseif strcmp(key, 'min_variance') + params.minVariance = value; + elseif startsWith(key, 'interval_scale ') + params.scaleKeys{end+1} = key(numel('interval_scale ')+1:end); + params.scales(end+1) = value; + end + end + k = k + 1; +end +header = strsplit(lines{k}, '\t'); +rows = lines(k+1:end); +rows = rows(~cellfun(@isempty, strtrim(rows))); +fields = cellfun(@(r) strsplit(r, '\t', 'CollapseDelimiters', false), rows, 'UniformOutput', false); +fields = vertcat(fields{:}); +col = @(name) fields(:, strcmp(header, name)); +params.source = col('source'); +params.bin = col('bin'); +params.bias = str2double(col('bias')); +params.variance = str2double(col('variance')); +end + +function c = combineKcats(names, lists, openRxns, params) +% One kcat per reaction from several sources: each source's value corrected +% for its bias and weighted by 1 / its error variance, both for the +% source's evidence bin (see evidenceBin). Several rows of one source for a +% reaction give their median, with the bin of best evidence; a value +% without a known bin gets the source's largest variance. geckopy's +% combine_kcats does the same. +unknown = setdiff(names, params.source); +if ~isempty(unknown) + error('collectKcats:combine', 'No combination parameters for %s; known sources: %s.', ... + strjoin(unknown, ', '), strjoin(unique(params.source), ', ')) +end +R = {}; S = {}; X = []; W = []; V = []; +for k = 1:numel(names) + name = names{k}; + list = lists{k}; + keep = ismember(list.rxns, openRxns) & list.kcats > 0 & isfinite(list.kcats); + rxns = list.rxns(keep); + values = log10(list.kcats(keep)); + details = list.detail(keep); + mine = strcmp(params.source, name); + srcBins = params.bin(mine); + srcBias = params.bias(mine); + srcVar = params.variance(mine); + [~, worst] = max(srcVar); + [u, ~, g] = unique(rxns, 'stable'); + for r = 1:numel(u) + rows = find(g == r); + bins = cellfun(@(d) evidenceBin(name, d), details(rows), 'UniformOutput', false); + [found, where] = ismember(bins, srcBins); + if any(found) + [~, best] = min(srcVar(where(found))); + pick = where(found); + pick = pick(best); + else + pick = worst; + end + R{end+1, 1} = u{r}; %#ok + S{end+1, 1} = name; %#ok + V(end+1, 1) = median(values(rows)); %#ok + X(end+1, 1) = median(values(rows)) - srcBias(pick); %#ok + W(end+1, 1) = 1 / max(srcVar(pick), params.minVariance); %#ok + end +end +[u, ~, g] = unique(R, 'stable'); +c.rxns = u; +n = numel(u); +c.kcats = zeros(n, 1); c.sd = zeros(n, 1); c.n = zeros(n, 1); c.spread = zeros(n, 1); +for r = 1:n + rows = g == r; + w = W(rows); + c.kcats(r) = 10 ^ (sum(w .* X(rows)) / sum(w)); + srcs = S(rows); + hasOkp = any(startsWith(srcs, 'okp_')); + hasTree = any(strcmp(srcs, 'ec_tree')); + if hasTree && hasOkp + key = 'ec_tree+okp'; + elseif hasOkp + key = 'okp'; + elseif hasTree + key = 'ec_tree+homologs'; + else + key = ''; + end + scale = 1; + hit = strcmp(params.scaleKeys, key); + if any(hit) + scale = params.scales(find(hit, 1)); + end + c.sd(r) = sqrt(1 / sum(w) + params.measurementSd ^ 2) * scale; + c.n(r) = sum(rows); + c.spread(r) = max(V(rows)) - min(V(rows)); +end +end + +function b = evidenceBin(source, detail) +% The evidence bin of a source's value, from its detail column. +b = ''; +if strcmp(source, 'ec_tree') + n = regexp(detail, 'n=(\d+)', 'tokens', 'once'); + depth = regexp(detail, 'depth=(\d)', 'tokens', 'once'); + if ~isempty(depth) && strcmp(depth{1}, '4') && ~isempty(n) + v = str2double(n{1}); + edges = [2 5 20 100]; + labels = {'1-2', '3-5', '6-20', '21-100', '>100'}; + b = ['ec4:' labels{find([v <= edges, true], 1)}]; + elseif ~isempty(depth) + b = ['ec' depth{1}]; + else + b = 'ec0'; + end +elseif strcmp(source, 'homologs') + t = regexp(detail, 'identity=([\d.]+)', 'tokens', 'once'); + if ~isempty(t) && str2double(t{1}) >= 0.95 + b = 'exact'; % the same protein: an assumed bin, see kcatCombineParams.tsv + elseif ~isempty(t) + labels = {'40', '50', '60', '70', '80', '90'}; + b = labels{find([str2double(t{1}) <= [0.5 0.6 0.7 0.8 0.9], true], 1)}; + end +elseif startsWith(source, 'okp_') + t = regexp(detail, 'similarity=([\d.]+)', 'tokens', 'once'); + if ~isempty(t) + labels = {'<40', '40-60', '60-80', '>80'}; + b = labels{find([str2double(t{1}) <= [40 60 80], true], 1)}; + end +end +end diff --git a/src/gather_kcats/convertCustomKcats.m b/src/gather_kcats/convertCustomKcats.m new file mode 100644 index 00000000..c1d5aaf8 --- /dev/null +++ b/src/gather_kcats/convertCustomKcats.m @@ -0,0 +1,152 @@ +function [file, report] = convertCustomKcats(model, varargin) +% convertCustomKcats Convert data/customKcats.tsv into data/kcats/custom.tsv. +% +% Writes the custom kcats of a GECKO 3 project as the curated kcat source +% file data/kcats/custom.tsv, which collectKcats reads first. The kcats are +% those applyCustomKcats gives the ecModel, including which of two entries +% for the same reaction wins: one row per reaction, keyed by conventional +% reaction and enzyme set (see getEcRxnKeys), with the entry's notes in the +% note column. The stoicho column is left out: complex stoichiometry comes +% from applyComplexData. Unlike applyCustomKcats, custom.tsv also applies to +% light ecModels. geckopy has the same (convert_custom_kcats). +% +% Parameters +% ---------- +% model : struct +% the full ecModel the custom kcats are for (with EC data). +% +% Name-Value Arguments +% -------------------- +% modelAdapter : ModelAdapter +% a loaded model adapter (default: the current default model adapter). +% customKcats : char +% the file to convert (default: data/customKcats.tsv in the project). +% outFile : char +% the file to write (default: data/kcats/custom.tsv in the project). An +% existing file is not overwritten. +% +% Returns +% ------- +% file : char +% the file written. +% report : struct +% - rows: number of rows written; +% - partial: reactions whose enzymes only partly match an entry, which +% applyCustomKcats does not change either (its notMatch). +% +% Examples +% -------- +% convertCustomKcats(ecModel); % then collectKcats/assignKcats read custom.tsv +% +% See also +% -------- +% collectKcats, applyCustomKcats, getEcRxnKeys, upgradeGECKOproject + +checkOptions(varargin, {'modelAdapter','customKcats','outFile'}, 'convertCustomKcats'); +p = parseGECKOargs(varargin, {'modelAdapter', []; 'customKcats', []; 'outFile', []}); +modelAdapter = p.modelAdapter; +if isempty(modelAdapter) + modelAdapter = ModelAdapterManager.getDefault(); + if isempty(modelAdapter) + error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.') + end +end +if model.ec.geckoLight + error('convertCustomKcats:light', ['applyCustomKcats does not work on light ecModels; give ' ... + 'the full ecModel. The custom.tsv written applies to light ecModels too.']) +end +inFile = p.customKcats; +if isempty(inFile) + inFile = fullfile(modelAdapter.params.path, 'data', 'customKcats.tsv'); +end +file = p.outFile; +if isempty(file) + file = fullfile(modelAdapter.params.path, 'data', 'kcats', 'custom.tsv'); +end +if ~isfile(inFile) + error('convertCustomKcats:missing', 'No custom kcats file %s.', inFile) +end +if isfile(file) + error('convertCustomKcats:exists', '%s exists and is not overwritten.', file) +end + +base = model; +base.ec.notes(:) = {''}; +[applied, rxnUpdated, notMatch] = applyCustomKcats(base, 'customKcats', inFile, 'modelAdapter', modelAdapter); +idx = find(ismember(applied.ec.rxns, rxnUpdated)); +[baseRxns, enzymeSets] = getEcRxnKeys(applied); +rows = strings(numel(idx), 9); +for k = 1:numel(idx) + i = idx(k); + note = regexprep(applied.ec.notes{i}, '[\t\r\n]', ' '); + rows(k, :) = [string(baseRxns{i}), string(enzymeSets{i}), "", formatNumber(applied.ec.kcat(i)), ... + "", "custom", "", "", string(note)]; +end +% Isozymic copies of one conventional reaction share a key and a value. +if ~isempty(rows) + [~, first] = unique(join(rows(:, 1:2), char(1), 2), 'stable'); + rows = rows(sort(first), :); + [~, order] = sort(join(rows(:, [1 2 3 6 4 5 7 8 9]), char(1), 2)); + rows = rows(order, :); +end + +folder = fileparts(file); +if ~isfolder(folder) + mkdir(folder); +end +gecko = geckoVersion(); +[~, name, ext] = fileparts(inFile); +fid = fopen(file, 'w', 'n', 'UTF-8'); +fprintf(fid, '# source: custom\n'); +fprintf(fid, '# generator: convertCustomKcats (GECKO %s)\n', gecko); +fprintf(fid, '# parameters: {}\n'); +fprintf(fid, '# data: %s\n', [name ext]); +fprintf(fid, '# kind: curated\n'); +fprintf(fid, '# created: %s\n', char(datetime('now', 'TimeZone', 'UTC', 'Format', 'yyyy-MM-dd''T''HH:mm:ss''Z'''))); +fprintf(fid, 'rxn\tenzymes\tsubstrate\tkcat\tlog10_sd\tsource\tdetail\tec_code\tnote\n'); +if ~isempty(rows) + fprintf(fid, '%s\n', join(rows, sprintf('\t'), 2)); +end +fclose(fid); +report.rows = size(rows, 1); +report.partial = notMatch; +fprintf('%d custom kcats written to %s.\n', report.rows, file); +end + +function t = formatNumber(x) +% The shortest text that reads back as x, as saveKcatSource writes numbers. +if x == round(x) && abs(x) < 1e15 + t = string(sprintf('%d', x)); + return +end +for digits = 1:17 + t = string(sprintf(sprintf('%%.%dg', digits), x)); + if str2double(t) == x + return + end +end +end + +function checkOptions(args, names, functionName) +% Options are name-value pairs with known names, so a misspelled option is +% an error instead of being taken as a positional argument. +id = [functionName ':arguments']; +given = args(1:2:end); +if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given)) + error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', ')) +end +unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names); +if ~isempty(unknown) + error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ... + strjoin(names, ', ')) +end +end + +function v = geckoVersion() +file = fullfile(findGECKOroot(), 'version.txt'); +if isfile(file) + v = strtrim(fileread(file)); +else + v = 'unknown'; +end +end diff --git a/src/gather_kcats/ecStatsFromBrenda.m b/src/gather_kcats/ecStatsFromBrenda.m index 45775ebf..e14b291d 100644 --- a/src/gather_kcats/ecStatsFromBrenda.m +++ b/src/gather_kcats/ecStatsFromBrenda.m @@ -1,41 +1,61 @@ -function ecStats = ecStatsFromBrenda(KCATcell,SAcell) +function ecStats = ecStatsFromBrenda(KCATcell,SAcell,KCATmedianCell) % ecStatsFromBrenda Summarise loadBRENDAdata's output per EC number, for % reviewKcatAssignment's ecStats argument. % -% TODO: verify against a real BRENDA pull before relying on this. Ported -% from geckopy's ec_stats_from_brenda without being able to run it -% against real BRENDA data in this environment. In particular, -% loadBRENDAdata's KCATcell only carries the BRENDA *max* aggregate per -% (EC, substrate, organism) triple (column 4 of kcat.tsv) -- the median -% column is read internally but discarded before KCATcell is returned -- -% so kcatMedian below is always NaN, and reviewKcatAssignment's -% "ec-maximum" check (which needs a finite kcatMedian) will never fire -% until loadBRENDAdata is extended to also expose it. +% loadBRENDAdata returns one aggregate of kcat.tsv per call, so the maximum +% view and the median view come from two calls: +% +% [KCATcell, SAcell] = loadBRENDAdata('kcatAggregation', 'max'); +% KCATmedianCell = loadBRENDAdata('kcatAggregation', 'median'); +% ecStats = ecStatsFromBrenda(KCATcell, SAcell, KCATmedianCell); +% +% geckopy's ec_stats_from_brenda gives the same statistics. The EC numbers +% keep the case they have in the BRENDA files. % % Parameters % ---------- % KCATcell : cell -% as returned by loadBRENDAdata's first output: {ecCode, substrate, -% organism, kcatMax}. +% first output of loadBRENDAdata with kcatAggregation 'max': {ecCode, +% substrate, organism, kcatMax}. % SAcell : cell -% as returned by loadBRENDAdata's second output: {ecCode, organism, -% kcatFromSA, mw}. +% second output of loadBRENDAdata with kcatAggregation 'max': {ecCode, +% organism, kcatFromSA, mw}. +% KCATmedianCell : cell +% first output of loadBRENDAdata with kcatAggregation 'median' +% (optional). Without it kcatMedian is NaN, so reviewKcatAssignment +% cannot flag 'ec-maximum', and a warning is given. % % Returns % ------- % ecStats : containers.Map -% EC code -> struct(nKcat,kcatMax,kcatMedian,values,nSa), keyed by -% the same (uppercased) EC strings BRENDA uses. +% EC code -> struct(nKcat,kcatMax,kcatMedian,values,nSa). nKcat and +% kcatMax are the number and the maximum of the kcat rows of the +% maximum view, kcatMedian is the median over the rows of the median +% view, values holds the kcat values of both views rounded to six +% decimals, and nSa is the number of specific-activity rows. % % See also % -------- % reviewKcatAssignment, loadBRENDAdata -ecCol = upper(KCATcell{1}); +ecCol = KCATcell{1}; maxCol = KCATcell{4}; +hasMedian = nargin >= 3 && ~isempty(KCATmedianCell) && ~isempty(KCATmedianCell{1}); +if nargin < 3 + warning('ecStatsFromBrenda:noMedianView', ... + ['No median view of the kcat rows was given, so kcatMedian is NaN ' ... + 'and reviewKcatAssignment cannot flag ec-maximum.']) +end +medEcCol = {}; +medCol = []; +if hasMedian + medEcCol = KCATmedianCell{1}; + medCol = KCATmedianCell{4}; +end + saEcCol = {}; if ~isempty(SAcell) && numel(SAcell) >= 1 && ~isempty(SAcell{1}) - saEcCol = upper(SAcell{1}); + saEcCol = SAcell{1}; end ecList = unique([ecCol(:); saEcCol(:)]); @@ -46,12 +66,21 @@ nKcat = sum(rows); if nKcat > 0 kcatMax = max(maxCol(rows)); - values = unique(round(maxCol(rows),6)); + values = round(maxCol(rows),6); else kcatMax = NaN; values = []; end + kcatMedian = NaN; + if hasMedian + medRows = strcmp(medEcCol,ec); + if any(medRows) + kcatMedian = median(medCol(medRows),'omitnan'); + values = [values(:); round(medCol(medRows),6)]; + end + end + values = unique(values(:)); nSa = sum(strcmp(saEcCol,ec)); - ecStats(ec) = struct('nKcat',nKcat,'kcatMax',kcatMax,'kcatMedian',NaN,'values',values,'nSa',nSa); + ecStats(ec) = struct('nKcat',nKcat,'kcatMax',kcatMax,'kcatMedian',kcatMedian,'values',values,'nSa',nSa); end end diff --git a/src/gather_kcats/ecTreeEstimate.m b/src/gather_kcats/ecTreeEstimate.m new file mode 100644 index 00000000..6b6fc8b2 --- /dev/null +++ b/src/gather_kcats/ecTreeEstimate.m @@ -0,0 +1,122 @@ +function [log10kcat, n, depth, ecUsed] = ecTreeEstimate(eccodes, measurements, k) +% ecTreeEstimate EC-tree kcat estimates for EC numbers. +% +% For each EC number, the median log10 kcat of its measurements is pulled +% toward the estimate of its parent class with weight n / (n + k), where n +% is the number of measurements: the global median, then the 2-digit +% class, the 3-digit class and the full EC number, in that order. A +% well-measured EC keeps its own median; a sparsely measured one leans on +% its class. geckopy has the same (geckopy.gather_kcats.ec_tree.ECTree). +% +% Parameters +% ---------- +% eccodes : cell +% per query one or more EC numbers separated by ';'. The one with most +% measurements of its full EC is used (the first on a tie). +% measurements : struct +% BRENDA measurement table with fields ec and log10kcat (see +% loadBrendaMeasurements). +% k : double +% shrinkage constant (default 5): the number of measurements at which +% an EC's own median and its class count equally. +% +% Returns +% ------- +% log10kcat : double +% the estimates; the global median for queries without measurements. +% n : double +% number of measurements of the full EC number used. +% depth : double +% deepest EC level with measurements: 4, 3, 2, or 0 when there are +% none (or no EC number). +% ecUsed : cell +% the EC number used. +% +% Examples +% -------- +% m = loadBrendaMeasurements(); +% [v, n, depth] = ecTreeEstimate({'1.1.1.1'; '2.7.1.1;2.7.1.2'}, m); +% kcat = 10.^v; +% +% See also +% -------- +% kcatsFromECTree, loadBrendaMeasurements + +if nargin < 3 || isempty(k) + k = 5; +end +if ~(isnumeric(k) && isscalar(k) && k > 0) + error('ecTreeEstimate:k', 'k must be a positive number.') +end +if ischar(eccodes) || isstring(eccodes) + eccodes = cellstr(eccodes); +end +ec = measurements.ec(:); +v = measurements.log10kcat(:); +globalMedian = median(v); +lv = cell(4, 1); +for d = [2 3 4] + if d == 4 + key = ec; + else + key = cellfun(@(e) parentEC(e, d), ec, 'UniformOutput', false); + end + [keys, ~, g] = unique(key); + lv{d} = struct('keys', {keys}, 'median', accumarray(g, v, [], @median), ... + 'n', accumarray(g, 1)); +end + +nq = numel(eccodes); +log10kcat = repmat(globalMedian, nq, 1); +n = zeros(nq, 1); +depth = zeros(nq, 1); +ecUsed = repmat({''}, nq, 1); +for q = 1:nq + ecs = strtrim(strsplit(char(eccodes{q}), ';')); + ecs = ecs(~cellfun(@isempty, ecs)); + if isempty(ecs) + continue + end + best = ecs{1}; + bestN = -1; + for e = 1:numel(ecs) + c = countOf(lv{4}, ecs{e}); + if c > bestN + best = ecs{e}; + bestN = c; + end + end + value = globalMedian; + for d = [2 3 4] + if d == 4 + key = best; + else + key = parentEC(best, d); + end + [c, med] = countOf(lv{d}, key); + if c > 0 + w = c / (c + k); + value = w * med + (1 - w) * value; + depth(q) = d; + end + end + log10kcat(q) = value; + n(q) = bestN; + ecUsed{q} = best; +end +end + +function p = parentEC(ec, d) +parts = strsplit(ec, '.'); +p = strjoin(parts(1:min(d, numel(parts))), '.'); +end + +function [c, med] = countOf(level, key) +[found, i] = ismember(key, level.keys); +c = 0; +med = NaN; +if found + c = level.n(i); + med = level.median(i); +end +end diff --git a/src/gather_kcats/extractEnzymeSubstratePairs.m b/src/gather_kcats/extractEnzymeSubstratePairs.m new file mode 100644 index 00000000..fc8a2800 --- /dev/null +++ b/src/gather_kcats/extractEnzymeSubstratePairs.m @@ -0,0 +1,141 @@ +function pairs = extractEnzymeSubstratePairs(model, varargin) +% extractEnzymeSubstratePairs The enzyme-substrate pairs of an ecModel's reactions. +% +% Lists, for each model.ec reaction, its enzymes and its substrates as +% DLKcat and the homolog search use them: the reactants of the reaction, +% without the metabolites of DLKcatIgnoreMets.tsv (metal ions, small +% molecules), without protein pseudometabolites, and without currency +% metabolites of DLKcatCurrencyMets.tsv where both members of a pair take +% part (unless no other substrate remains). Both files are read from the +% data folder of the project, or else from the databases folder of GECKO. +% geckopy has the same (extract_enzyme_substrate_pairs). +% +% Parameters +% ---------- +% model : struct +% an ecModel in GECKO 3 format (with ecModel.ec structure). +% +% Name-Value Arguments +% -------------------- +% ecRxns : logical +% which model.ec.rxns to list (default: all). +% modelAdapter : ModelAdapter +% a loaded model adapter (default: the current default model adapter). +% +% Returns +% ------- +% pairs : struct +% ecRxn (index into model.ec.rxns), protein (index into model.ec.genes, +% model.ec.enzymes and model.ec.sequence) and met (index into +% model.mets), one entry per pair, reaction by reaction. +% +% Examples +% -------- +% pairs = extractEnzymeSubstratePairs(ecModel); +% model.metNames(pairs.met(1:5)) +% +% See also +% -------- +% writeDLKcatInput, kcatsFromHomologs + +[geckoPath, ~] = findGECKOroot(); +p = parseGECKOargs(varargin, {'ecRxns', []; 'modelAdapter', []}); +ecRxnsSel = p.ecRxns; +if isempty(ecRxnsSel) + ecRxnsSel = true(numel(model.ec.rxns),1); +elseif ~islogical(ecRxnsSel) + error('ecRxns should be provided as logical vector') +elseif numel(ecRxnsSel)~=numel(model.ec.rxns) + error('Length of ecRxns is not the same as model.ec.rxns') +end +ecRxnsSel = find(ecRxnsSel); +modelAdapter = p.modelAdapter; +if isempty(modelAdapter) + modelAdapter = ModelAdapterManager.getDefault(); + if isempty(modelAdapter) + error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.') + end +end +params = modelAdapter.params; + +if ~model.ec.geckoLight + origRxns = model.ec.rxns; +else + origRxns = extractAfter(model.ec.rxns,4); +end +origRxnsToInclude = origRxns(ecRxnsSel); + +% Map back to original reactions, to extract substrates +[sanityCheck,origRxnIdxs] = ismember(origRxnsToInclude,model.rxns); +if ~all(sanityCheck) + error('Not all reactions in model.ec.rxns are found in model.rxns') +end + +% Ignore selected metabolites (metal ions, proteins etc.). First check by +% name (case insensitive, without white spaces and special characters), +% then also try to match with metSmiles (if available). +metsNoSpecialChars = lower(regexprep(model.metNames,'[^0-9a-zA-Z]+','')); +if exist(fullfile(params.path,'data','DLKcatIgnoreMets.tsv'),'file') + fID = fopen(fullfile(params.path,'data','DLKcatIgnoreMets.tsv')); +else + fID = fopen(fullfile(geckoPath,'databases','DLKcatIgnoreMets.tsv')); +end +fileData = textscan(fID,'%s %s','delimiter','\t'); +fclose(fID); +[ignoreMets, ignoreSmiles] = deal(fileData{[1,2]}); +ignoreMets = lower(regexprep(ignoreMets,'[^0-9a-zA-Z]+','')); +ignoreSmiles(cellfun(@isempty,ignoreSmiles)) = []; + +ignoreMetsIdx = logical(ismember(metsNoSpecialChars,ignoreMets)); +if isfield(model,'metSmiles') + ignoreMetsIdx = ignoreMetsIdx | logical(ismember(model.metSmiles,ignoreSmiles)); +end +% Also leave out protein-usage pseudometabolites +ignoreMetsIdx = ignoreMetsIdx | startsWith(model.mets,'prot_'); +reducedS = model.S; +reducedS(ignoreMetsIdx,:) = 0; + +% Ignore currency metabolites if they occur in pairs. First check by +% name (case insensitive, without white spaces and special characters), +% then also try to match with metSmiles (if available). +if exist(fullfile(params.path,'data','DLKcatCurrencyMets.tsv'),'file') + fID = fopen(fullfile(params.path,'data','DLKcatCurrencyMets.tsv')); +else + fID = fopen(fullfile(geckoPath,'databases','DLKcatCurrencyMets.tsv')); +end +fileData = textscan(fID,'%s %s','delimiter','\t'); +fclose(fID); +[currencyMets(:,1), currencyMets(:,2)] = deal(fileData{[1,2]}); +currencyMets = lower(regexprep(currencyMets,'[^0-9a-zA-Z]+','')); + +for i=1:size(currencyMets,1) + subs = strcmp(currencyMets(i,1),metsNoSpecialChars); + prod = strcmp(currencyMets(i,2),metsNoSpecialChars); + [~,subsRxns]=find(reducedS(subs,:)); + [~,prodRxns]=find(reducedS(prod,:)); + pairRxns = intersect(subsRxns,prodRxns); + tempRedS=reducedS; + tempRedS([find(subs);find(prod)],pairRxns) = 0; + % Do not remove currency mets if no substrate remains + rxnsWithRemainingSubstrates = any(tempRedS(:,pairRxns) < 0,1); + reducedS([find(subs);find(prod)],intersect(pairRxns,pairRxns(rxnsWithRemainingSubstrates))) = 0; +end + +% origRxnIdxs already selects exactly the model.rxns columns for the requested +% ecRxns subset (one column per requested reaction, via origRxns(ecRxns) above), so +% clearedRedS needs no further filtering here. +clearedRedS = reducedS(:,origRxnIdxs); + +% Enumerate all substrates for each reaction. clearedRedS has one column per entry +% of ecRxnsSel, in that same order, so `reactions` here indexes *that subset*, not +% model.ec.rxns directly --- translate back to a real model.ec.rxns index before +% using it against model.ec.rxns / model.ec.rxnEnzMat, which are always full-length. +[substrates, reactions] = find(clearedRedS<0); +globalEcRxns = ecRxnsSel(reactions); + +% Enumerate all proteins for each reaction +[proteins, enzRows] = find(transpose(model.ec.rxnEnzMat(globalEcRxns,:))); +pairs.ecRxn = reshape(globalEcRxns(enzRows), [], 1); +pairs.protein = reshape(proteins, [], 1); +pairs.met = reshape(substrates(enzRows), [], 1); +end diff --git a/src/gather_kcats/fetchOpenKineticsPredictor.m b/src/gather_kcats/fetchOpenKineticsPredictor.m index a992f856..1666e498 100644 --- a/src/gather_kcats/fetchOpenKineticsPredictor.m +++ b/src/gather_kcats/fetchOpenKineticsPredictor.m @@ -29,6 +29,9 @@ % return (default false). % pollInterval : double % seconds between polls when wait=true (default 30). +% outFile : char +% where the result is stored, and read from with useStored=true +% (default: data/OKP_output.csv). % modelAdapter : ModelAdapter % a loaded model adapter (default: the current default model adapter). % @@ -56,7 +59,8 @@ 'jobId', []; ... 'wait', []; ... 'pollInterval', []; ... - 'modelAdapter', []}); + 'modelAdapter', []; ... + 'outFile', []}); useStored = p.useStored; jobId = p.jobId; wait = p.wait; @@ -74,7 +78,10 @@ if isempty(wait); wait = false; end if isempty(pollInterval); pollInterval = 30; end -outFile = fullfile(params.path,'data','OKP_output.csv'); +outFile = p.outFile; +if isempty(outFile) + outFile = fullfile(params.path,'data','OKP_output.csv'); +end %% Stored-result mode: parse the saved file, no API call if useStored diff --git a/src/gather_kcats/fuzzyKcatMatching.m b/src/gather_kcats/fuzzyKcatMatching.m index 7e77c32c..d9787111 100644 --- a/src/gather_kcats/fuzzyKcatMatching.m +++ b/src/gather_kcats/fuzzyKcatMatching.m @@ -18,14 +18,20 @@ % % Name-Value Arguments % -------------------- -% ecRxns : logical +% ecRxns : logical or double % for which reactions (from model.ec.rxns) kcat values should be found, -% provided as logical vector with same length as model.ec.rxns -% (default: all reactions). +% provided as a logical vector with the same length as model.ec.rxns +% (the reactions are returned in model order), or as indices into +% model.ec.rxns (the reactions are returned in the order given, and an +% index given twice is returned twice). The literal [] selects all +% reactions, which is the default; any other empty selection, such as +% find(mask) without true entries, selects none and returns an empty +% kcatList. % modelAdapter : ModelAdapter % a loaded model adapter (default: the current default model adapter). % forceWClvl : double -% force a minimum wildcard level (default 0). +% number of extra levels, from the right, replaced by a wildcard (on top +% of any wildcard already in the code; default 0). % % Returns % ------- @@ -43,7 +49,8 @@ % - kcats : proposed kcat value in /sec. % - eccodes : as used to query BRENDA. % - wildcardLvl : which level of EC wild-card was necessary to find a match -% (0: w.x.y.z; 1: w.x.y.-; 2: w.x.-.-; 3: w.-.-.-). +% (0: w.x.y.z; 1: w.x.y.-; 2: w.x.-.-; 3: w.-.-.-; 4: -.-.-.-, which +% matches every EC number in BRENDA). % - origin : which level of specificity was necessary to find a match % (1: correct organism, correct substrate, kcat; 2: any organism, correct % substrate, kcat; 3: correct organism, any substrate, kcat; 4: any @@ -52,7 +59,9 @@ % 1, 2, 3, 5, 4, 6: a specific activity from the correct organism is % preferred over a kcat from any organism with any substrate. When a % reaction has multiple EC numbers, the EC with the fewest wildcards and -% the earliest-tried level is selected, and among those the highest kcat. +% the earliest-tried level is selected, and among those the highest kcat +% (the first one when several EC numbers share it); the wildcardLvl and +% origin are those of the selected EC. % % If a wildcard is used, origin levels 1 and 2 are ignored. The last digits % in the E.C. number indicate the substrate specificity, so if this should @@ -68,22 +77,44 @@ % -------- % mergeDLKcatAndFuzzyKcats, assignKcatValues +% Validators reject a name that landed in a positional slot, which +% happens when positional and name-value arguments are mixed. Without +% them `while forceWClvl > 0` on a char array is all-true and silently +% wildcards every EC number. p = parseGECKOargs(varargin, { ... - 'ecRxns', []; ... - 'modelAdapter', []; ... - 'forceWClvl', []}); -ecRxns = p.ecRxns; -modelAdapter = p.modelAdapter; -forceWClvl = p.forceWClvl; - -if isempty(ecRxns) - ecRxns = true(numel(model.ec.rxns),1); -elseif isnumeric(ecRxns) - ecRxnsVec = false(numel(model.ec.rxns),1); - ecRxnsVec(ecRxns) = true; - ecRxns = ecRxnsVec; + 'ecRxns', [], @(x) assert(isempty(x) || isnumeric(x) || ... + islogical(x), ... + 'fuzzyKcatMatching:invalidEcRxns', ... + 'ecRxns must be numeric or logical.'); ... + 'modelAdapter', [], @(x) assert(isempty(x) || isa(x,'ModelAdapter'), ... + 'fuzzyKcatMatching:invalidModelAdapter', ... + 'modelAdapter must be a ModelAdapter.'); ... + 'forceWClvl', [], @(x) assert(isempty(x) || (isnumeric(x) && ... + isscalar(x) && x >= 0), ... + 'fuzzyKcatMatching:invalidForceWClvl', ... + 'forceWClvl must be a nonnegative scalar.'); ... + 'kcatAggregation', [], @(x) assert(isempty(x) || any(strcmpi(x, ... + {'max','median'})), ... + 'fuzzyKcatMatching:invalidKcatAggregation', ... + 'kcatAggregation must be ''max'' or ''median''.')}); +ecRxns = p.ecRxns; +modelAdapter = p.modelAdapter; +forceWClvl = p.forceWClvl; +kcatAggregation = p.kcatAggregation; + +% Get indices: [] selects all reactions, a logical vector the true entries (in +% model order) and indices are used as given (order and repeats kept). +if isnumeric(ecRxns) && isequal(size(ecRxns),[0 0]) + ecRxns = (1:numel(model.ec.rxns)).'; +elseif islogical(ecRxns) + ecRxns = find(ecRxns(:)); +else + ecRxns = ecRxns(:); + if any(ecRxns < 1 | ecRxns > numel(model.ec.rxns) | ecRxns ~= round(ecRxns)) + error('fuzzyKcatMatching:invalidEcRxns', ... + 'ecRxns must hold indices of model.ec.rxns.'); + end end -ecRxns=find(ecRxns); % Get indices instead of logical if isempty(modelAdapter) modelAdapter = ModelAdapterManager.getDefault(); @@ -101,6 +132,17 @@ error('No EC codes defined in model.ec.eccodes. First run getECfromGEM() and/or getECfromDatabase().') end eccodes = model.ec.eccodes(ecRxns); +if isempty(ecRxns) + %No reactions selected: nothing to match, and BRENDA is not read + kcatList.source = 'brenda'; + kcatList.rxns = cell(0,1); + kcatList.substrates = cell(0,1); + kcatList.kcats = zeros(0,1); + kcatList.eccodes = cell(0,1); + kcatList.wildcardLvl = NaN(0,1); + kcatList.origin = NaN(0,1); + return +end substrates = cell(numel(ecRxns),1); substrCoeffs = cell(numel(ecRxns),1); @@ -118,7 +160,9 @@ end %Load BRENDA data: -[KCATcell, SAcell] = loadBRENDAdata(modelAdapter); +kcatAggregation = resolveKcatAggregation(kcatAggregation, modelAdapter); +[KCATcell, SAcell] = loadBRENDAdata('modelAdapter', modelAdapter, ... + 'kcatAggregation', kcatAggregation); %Creates a Structure with KEGG codes for organisms, names and taxonomical %distance matrix and extract the organism index in the KEGG struct @@ -179,10 +223,7 @@ end %Apply force wildcard level -while forceWClvl > 0 - eccodes=regexprep(eccodes,'(.)*(\.\d+)(\.-)*$','$1\.-$3'); - forceWClvl = forceWClvl - 1; -end +eccodes = forceWildcards(eccodes,forceWClvl); PB = progressReport(mM, 'Gathering kcat values by fuzzy matching to BRENDA database'); %Main loop: @@ -196,7 +237,7 @@ if ~isempty(substrates{i}) [kcats(i), kcatInfo.info,kcatInfo.stats] = iterativeMatch(EC,substrates{i},substrCoeffs{i},i,KCATcell,... kcatInfo.info,kcatInfo.stats,org_name,... - phylDistStruct,org_index,SAcell,ECIndexIds,EcIndexIndices); + phylDistStruct,org_index,SAcell,ECIndexIds,EcIndexIndices,kcatAggregation); end end end @@ -216,8 +257,38 @@ end end %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% +%Replaces the rightmost level of each EC code that is not a wildcard yet with +%a wildcard, forceWClvl times, so that level 4 gives -.-.-.- . The codes of one +%entry are separated by ';'. A code that does not have four levels is kept. +function eccodes = forceWildcards(eccodes,forceWClvl) +if forceWClvl <= 0 + return +end +for i = 1:numel(eccodes) + if isempty(eccodes{i}) + continue + end + codes = strsplit(eccodes{i},';'); + for j = 1:numel(codes) + parts = strsplit(codes{j},'.'); + if numel(parts) ~= 4 + continue + end + for k = 1:forceWClvl + last = find(~strcmp(parts,'-'),1,'last'); + if isempty(last) + break + end + parts{last} = '-'; + end + codes{j} = strjoin(parts,'.'); + end + eccodes{i} = strjoin(codes,';'); +end +end +%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% function [kcat,dir,tot] =iterativeMatch(EC,subs,substrCoeff,i,KCATcell,dir,tot,... - name,phylDist,org_index,SAcell,ECIndexIds,EcIndexIndices) + name,phylDist,org_index,SAcell,ECIndexIds,EcIndexIndices,kcatAggregation) %Will iteratively try to match the EC number to some registry in BRENDA, %using each time one additional wildcard. @@ -231,7 +302,7 @@ %Atempt match: [kcat(k),origin(k),matches(k)] = mainMatch(EC{k},subs,substrCoeff,KCATcell,... name,phylDist,... - org_index,SAcell,ECIndexIds,EcIndexIndices); + org_index,SAcell,ECIndexIds,EcIndexIndices,kcatAggregation); %If any match found, ends. If not, introduces one extra wild card and %tries again: if origin(k) > 0 @@ -239,12 +310,20 @@ wc_num(k) = sum(EC{k}=='-'); else wild_num = sum(EC{k}=='-'); - if wild_num >= 4 + if numel(strsplit(EC{k},'.')) ~= 4 + %An EC code without four levels (for example '1.1.1') cannot be + %escalated level by level: stop with the no-match values, as + %geckopy does. + success = true; + elseif wild_num >= 4 %Already fully wildcarded ('-.-.-.-') and still no match -- %stop here instead of computing dot_pos(4-wild_num) with %wild_num==4, an out-of-range index. kcat(k)/origin(k) keep %their zero-initialised "no match" values. success = true; + elseif wild_num == 3 + %Last escalation: '-.-.-.-' matches every EC number in BRENDA + EC{k} = '-.-.-.-'; else dot_pos = [2 strfind(EC{k},'.')]; wc_text = '-.-.-.-'; @@ -265,11 +344,14 @@ %(higher) wildcard count back in whenever it happens to share best_origin, %defeating the wildcard-count filter entirely. best_pos = best_pos & (origin == best_origin); - max_pos = find(kcat == max(kcat(best_pos))); - wc_num = wc_num(max_pos(1)); - origin = origin(max_pos(1)); - matches = matches(max_pos(1)); - kcat = kcat(max_pos(1)); + %Highest kcat among those, the first one if several share it + best_idx = find(best_pos); + [~,j] = max(kcat(best_idx)); + max_pos = best_idx(j); + wc_num = wc_num(max_pos); + origin = origin(max_pos); + matches = matches(max_pos); + kcat = kcat(max_pos); %Update dir and tot: dir.org_s(i) = matches*(origin == 1); @@ -298,7 +380,7 @@ %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% function [kcat,origin,matches] = mainMatch(EC,subs,substrCoeff,KCATcell,... - name,phylDist,org_index,SAcell,ECIndexIds,EcIndexIndices) + name,phylDist,org_index,SAcell,ECIndexIds,EcIndexIndices,kcatAggregation) %First make the string matching. This takes time, so we only want to do %this once: @@ -317,19 +399,19 @@ origin = 0; %First try to match organism and substrate: [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,name,true,false,... - phylDist,org_index,SAcell,stringMatchesEC_cell,[]); + phylDist,org_index,SAcell,stringMatchesEC_cell,[],kcatAggregation); if matches > 0 && ~wild % If wildcard, ignore substrate match origin = 1; %If no match, try the closest organism but match the substrate: else [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,'',true,false,... - phylDist,org_index,SAcell,stringMatchesEC_cell,[]); + phylDist,org_index,SAcell,stringMatchesEC_cell,[],kcatAggregation); if matches > 0 && ~wild % If wildcard, ignore substrate match origin = 2; %If no match, try to match organism but with any substrate: else [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,name,false,false,... - phylDist,org_index,SAcell,stringMatchesEC_cell,[]); + phylDist,org_index,SAcell,stringMatchesEC_cell,[],kcatAggregation); if matches > 0 origin = 3; %If no match, try to match organism but for any substrate (SA*MW): @@ -339,21 +421,21 @@ [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,name,false,... true,phylDist,org_index,... - SAcell,stringMatchesEC_cell,stringMatchesSA); + SAcell,stringMatchesEC_cell,stringMatchesSA,kcatAggregation); if matches > 0 origin = 4; %If no match, try any organism and any substrate: else [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,'',false,... false,phylDist,... - org_index,SAcell,stringMatchesEC_cell,stringMatchesSA); + org_index,SAcell,stringMatchesEC_cell,stringMatchesSA,kcatAggregation); if matches > 0 origin = 5; %Again if no match, look for any org and SA*MW else [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,'',... false,true,phylDist,... - org_index,SAcell,stringMatchesEC_cell,stringMatchesSA); + org_index,SAcell,stringMatchesEC_cell,stringMatchesSA,kcatAggregation); if matches > 0 origin = 6; end @@ -367,7 +449,7 @@ %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% function [kcat,matches] = matchKcat(EC,subs,substrCoeff,KCATcell,organism,... substrate,SA,phylDist,... - org_index,SAcell,KCATcellMatches,SAcellMatches) + org_index,SAcell,KCATcellMatches,SAcellMatches,kcatAggregation) %Will go through BRENDA and will record any match. Afterwards, it will %return the maximum value and the number of matches attained. @@ -398,7 +480,7 @@ %l = logical(strcmpi(model.metNames,subs{k}).*(model.S(:,i)~=0)); %I don't understand the .* (model.S(:,i)~=0) part, it shouldn't be needed?/JG; if ~isempty(subs{k}) && strcmpi(subs{k},KCATcell{2}(indx)) if KCATcell{4}(indx) > 0 - coeff = min(substrCoeff); + coeff = substrCoeff(k); kCatTmp = KCATcell{4}(indx); kcat = [kcat;kCatTmp/coeff]; end @@ -409,12 +491,16 @@ kcat = KCATcell{4}(EC_indexes); end end -%Return maximum value: +%Collapse the matched entries to one value, by the chosen aggregation: if isempty(kcat) kcat = 0; else - matches = length(kcat); - [kcat,MaxIndx] = max(kcat); + matches = length(kcat); + if strcmpi(kcatAggregation,'median') + kcat = median(kcat); + else + kcat = max(kcat); + end end %Avoid SA*Mw values over the diffusion limit rate [Bar-Even et al. 2011] if kcat>(1E7) @@ -442,6 +528,8 @@ for j = 1:length(X) EC_indexes = [EC_indexes,EcIndexIndices{X(j)}]; end + elseif isempty(EC) %Not optimized, fully wildcarded: every entry matches + EC_indexes = 1:length(EC_cell); else %Not optimized for j=1:length(EC_cell) if strfind(EC_cell{j},EC)==1 diff --git a/src/gather_kcats/getEcRxnKeys.m b/src/gather_kcats/getEcRxnKeys.m new file mode 100644 index 00000000..652750ea --- /dev/null +++ b/src/gather_kcats/getEcRxnKeys.m @@ -0,0 +1,51 @@ +function [baseRxns, enzymeSets] = getEcRxnKeys(model) +% getEcRxnKeys Build-independent keys of the model.ec reactions. +% +% A kcat source file (see saveKcatSource) identifies a reaction by its +% conventional reaction and its enzyme set, not by model.ec.rxns, whose +% identifiers depend on how the ecModel was built. This function gives +% both keys for every model.ec row. +% +% Parameters +% ---------- +% model : struct +% an ecModel in GECKO 3 format (with ecModel.ec structure). +% +% Returns +% ------- +% baseRxns : cell +% per model.ec.rxns entry, the conventional reaction: without a +% trailing _EXP_ (full model) or a leading _ (light model). A +% reverse direction keeps its _REV. +% enzymeSets : cell +% per model.ec.rxns entry, the UniProt accessions of its enzymes +% (model.ec.rxnEnzMat), sorted and joined by ' + '; empty without +% enzymes. +% +% Examples +% -------- +% [baseRxns, enzymeSets] = getEcRxnKeys(ecModel); +% +% See also +% -------- +% saveKcatSource, loadKcatSource + +if model.ec.geckoLight + baseRxns = regexprep(model.ec.rxns, '^\d+_', ''); +else + baseRxns = regexprep(model.ec.rxns, '_EXP_\d+$', ''); +end +baseRxns = baseRxns(:); + +n = numel(model.ec.rxns); +enzymeSets = repmat({''}, n, 1); +[rows, cols] = find(model.ec.rxnEnzMat); +if ~isempty(rows) + % Enzymes per reaction in one pass, rather than a search per reaction. + perRxn = accumarray(rows(:), cols(:), [n 1], @(c) {c}); + for i = find(~cellfun(@isempty, perRxn))' + enzymes = unique(model.ec.enzymes(perRxn{i})); + enzymeSets{i} = strjoin(enzymes(:)', ' + '); + end +end +end diff --git a/src/gather_kcats/getStandardKcat.m b/src/gather_kcats/getStandardKcat.m index 7ebe2345..d1d9c867 100644 --- a/src/gather_kcats/getStandardKcat.m +++ b/src/gather_kcats/getStandardKcat.m @@ -15,7 +15,9 @@ % first subSystem will be considered if multiple are annotated to the same % reaction. % -% Exchange, transport and pseudoreactions are filtered out, plus any +% Exchange (RAVEN's getExchangeRxns: no substrate or no product), transport +% and pseudoreactions (a reaction name that contains 'pseudoreaction' or +% 'SLIME rxn', in any letter case) are filtered out, plus any % reaction identifiers specified in /data/pseudoRxns.tsv in the model % adapter folder. % @@ -133,13 +135,14 @@ end % Map ec-rxns to model.rxns [~,rxnIdx] = ismember(modRxns,model.rxns); - % Choose first subSystem - enzSubSystems = flattenCell(model.subSystems(rxnIdx)); - enzSubSystems = enzSubSystems(:,1); + % Choose first subSystem ('' when a reaction has none) + enzSubSystems = cellfun(@firstSubSystem, model.subSystems(rxnIdx), 'UniformOutput', false); if ~all(cellfun(@isempty, enzSubSystems)) - % Make list of unique subsystems, and which rxns are linked to them - [enzSubSystem_names, ~, rxnToSub] = unique(enzSubSystems); + % Make list of unique subsystems, and which rxns are linked to them. + % Names that differ only in letter case are one subSystem. + [~, firstOccurrence, rxnToSub] = unique(lower(enzSubSystems)); + enzSubSystem_names = enzSubSystems(firstOccurrence); % Calculate the median kcat per subSystem, counting only reactions % with a real (nonzero, non-NaN) kcat toward both the median itself % and the threshold that decides whether a subSystem-specific value @@ -196,14 +199,14 @@ [~, exchangeRxns] = getExchangeRxns(model); transportRxns = getTransportRxns(model); [spontaneousRxns, ~] = modelAdapter.getSpontaneousReactions(model); -pseudoRxns = contains(model.rxnNames,'pseudoreaction'); -slimeRxns = contains(model.rxnNames,'SLIME rxn'); +pseudoRxns = contains(lower(model.rxnNames),'pseudoreaction'); +slimeRxns = contains(lower(model.rxnNames),'slime rxn'); rxnsToIgnore = [customRxns; exchangeRxns; find(transportRxns); ... find(spontaneousRxns); find(pseudoRxns); find(slimeRxns)]; rxnsMissingGPR(ismember(rxnsMissingGPR, rxnsToIgnore)) = []; -% Only add if not geckoLight & getStandardKcat was not run earlier -if ~any(strcmp(model.mets,'prot_standard')) +% Only add if getStandardKcat was not run earlier +if ~any(strcmp(model.mets,'prot_standard')) && ~any(strcmp(model.ec.enzymes,'standard')) % Add a new gene to be consistent with ec field named standard proteinStdGenes.genes = 'standard'; if isfield(model,'geneShortNames') @@ -289,8 +292,9 @@ % all(), is the right test -- all() only ever succeeds when the model % has exactly one subSystem in total, silently falling back to the % model-wide standardKcat for every reaction otherwise. - kcatSubSystemIdx = strcmpi(enzSubSystem_names, model.subSystems{rxnIdx}(1)); - if any(kcatSubSystemIdx) + rxnSubSystem = firstSubSystem(model.subSystems{rxnIdx}); + kcatSubSystemIdx = strcmpi(enzSubSystem_names, rxnSubSystem); + if ~isempty(rxnSubSystem) && any(kcatSubSystemIdx) model.ec.kcat(end+1) = kcatSubSystem(kcatSubSystemIdx); else model.ec.kcat(end+1) = standardKcat; @@ -319,39 +323,14 @@ end end -function Cflat = flattenCell(C,strFlag) -%FLATTENCELL Flatten a nested column cell array into a matrix cell array. -% -% CFLAT = FLATTENCELL(C) takes a column cell array in which one or more -% entries is a nested cell array, and flattens it into a 2D matrix cell -% array, where the nested entries are spread across new columns. -% -% CFLAT = FLATTENCELL(C,STRFLAG) if STRFLAG is TRUE, empty entries in the -% resulting CFLAT will be replaced with empty strings {''}. Default = FALSE -if nargin < 2 - strFlag = false; -end - -% determine which entries are cells -cells = cellfun(@iscell,C); - -% determine number of elements in each nested cell -cellsizes = cellfun(@numel,C); -cellsizes(~cells) = 1; % ignore non-cell entries - -% flatten single-entry cells -Cflat = C; -Cflat(cells & (cellsizes == 1)) = cellfun(@(x) x{1},Cflat(cells & (cellsizes == 1)),'UniformOutput',false); - -% iterate through multi-entry cells -multiCells = find(cellsizes > 1); -for i = 1:length(multiCells) - cellContents = Cflat{multiCells(i)}; - Cflat(multiCells(i),1:length(cellContents)) = cellContents; -end - -% change empty elements to strings, if specified -if ( strFlag ) - Cflat(cellfun(@isempty,Cflat)) = {''}; +function name = firstSubSystem(subSystems) +% First subSystem of a reaction as a character vector; '' when the reaction +% has none. +if ischar(subSystems) + name = subSystems; +elseif iscell(subSystems) && ~isempty(subSystems) && ischar(subSystems{1}) + name = subSystems{1}; +else + name = ''; end end diff --git a/src/gather_kcats/kcatAssignmentConfig.m b/src/gather_kcats/kcatAssignmentConfig.m new file mode 100644 index 00000000..f6e1f57d --- /dev/null +++ b/src/gather_kcats/kcatAssignmentConfig.m @@ -0,0 +1,171 @@ +function config = kcatAssignmentConfig(params) +% kcatAssignmentConfig The kcat assignment settings of a model adapter. +% +% Reads [kcat_assignment] and [kcat_sources.*] of model_adapter.toml (or +% params.kcat_assignment and params.kcat_sources of an adapter class), and +% expands a preset into its stages, as collectKcats and updateKcatSources +% use them. Without a preset or stages the preset is brenda_ec_tree. An +% empty preset, an unknown criteria (the names are lower case), and a stage +% whose sources is not a list raise kcatAssignment:config. geckopy's +% kcat_assignment_config gives the same settings. +% +% Parameters +% ---------- +% params : struct +% the parameters of a model adapter (modelAdapter.params). +% +% Returns +% ------- +% config : struct +% - preset: the preset name, or '' when stages are given; +% - isozymes, standard: logical; +% - stages: struct array with action ('select' or 'combine'), sources +% (cell, as given), files (the source files they read, with okp +% replaced by the files of its methods), criteria, topOriginLimit, +% bottomOriginLimit and wildcardLimit; +% - okpMethods: the OKP methods of the okp source group ([kcat_sources.okp] +% methods; default all methods with combination parameters); +% - sources: per source name its options (from [kcat_sources] and the +% preset). +% +% Examples +% -------- +% config = kcatAssignmentConfig(modelAdapter.params); +% config.stages(1).sources % the order of the sources +% +% See also +% -------- +% collectKcats, assignKcats, updateKcatSources + +a = struct(); +if isfield(params, 'kcat_assignment') && isstruct(params.kcat_assignment) + a = params.kcat_assignment; +end +config.preset = ''; +config.isozymes = getOr(a, 'isozymes', true); +config.standard = getOr(a, 'standard', true); +config.sources = struct(); +hasPreset = isfield(a, 'preset') && ~(isnumeric(a.preset) && isempty(a.preset)); +if hasPreset && (~(ischar(a.preset) || isstring(a.preset)) || strlength(string(a.preset)) == 0) + error('kcatAssignment:config', 'The preset of [kcat_assignment] must be the name of a preset.') +end +hasStages = isfield(a, 'stage') && ~isempty(a.stage); +if hasPreset && hasStages + error('kcatAssignment:config', ['[kcat_assignment] gives both a preset and stages; ' ... + 'give one of the two.']) +end +if hasStages + config.stages = arrayfun(@readStage, a.stage(:)'); +else + preset = 'brenda_ec_tree'; + if hasPreset + preset = char(a.preset); + end + [config.stages, config.sources] = presetStages(preset); + config.preset = preset; +end +if isfield(params, 'kcat_sources') && isstruct(params.kcat_sources) + names = fieldnames(params.kcat_sources); + for k = 1:numel(names) + config.sources.(names{k}) = params.kcat_sources.(names{k}); + end +end +% The okp group: the OKP methods of [kcat_sources.okp] methods. +known = {'CataPro','CatPred','CatRange','DLKcat','EITLEM','KinForm-H','KinForm-L', ... + 'OmniESI','OmniESI-O2DENet','TurNup','UniKP'}; +% The default: methods that read enzyme-substrate pairs and have combination +% parameters (CatRange predicts classes; CatPred and TurNup read whole +% reactions, which kcatsFromOKP does not submit). +config.okpMethods = known(~ismember(known, {'CatRange', 'CatPred', 'TurNup'})); +if isfield(config.sources, 'okp') && isfield(config.sources.okp, 'methods') && ~isempty(config.sources.okp.methods) + config.okpMethods = cellstr(config.sources.okp.methods); + config.okpMethods = config.okpMethods(:)'; +end +unknown = setdiff(config.okpMethods, known); +if ~isempty(unknown) + error('kcatAssignment:config', 'Unknown OKP methods in [kcat_sources.okp] methods: %s; methods: %s.', ... + strjoin(unknown, ', '), strjoin(known, ', ')) +end +okpFiles = cellfun(@(m) ['okp_' lower(regexprep(regexprep(m, '[^A-Za-z0-9]+', '_'), '^_+|_+$', ''))], ... + config.okpMethods, 'UniformOutput', false); +for s = 1:numel(config.stages) + files = {}; + for t = config.stages(s).sources + if strcmp(t{1}, 'okp') + files = [files, okpFiles]; %#ok + else + files{end+1} = t{1}; %#ok + end + end + [~, first] = unique(files, 'stable'); + config.stages(s).files = files(sort(first)); +end +end + +function [stages, sources] = presetStages(preset) +% The presets of kcat assignment; geckopy defines the same. +stage = @(action, srcs, top) struct('action', action, 'sources', {srcs}, 'criteria', 'max', ... + 'topOriginLimit', top, 'bottomOriginLimit', 6, 'wildcardLimit', 3); +order = {'custom', 'database_top', 'dlkcat', 'database_bottom'}; +own = {'custom', 'database_top'}; % with topOriginLimit 1: the organism's own BRENDA value +sources = struct(); +switch preset + case 'brenda_ec_tree' + stages = [stage('select', [own, {'ec_tree'}], 1), stage('combine', {'okp'}, 4)]; + sources.brenda = struct('aggregation', 'median'); + sources.ec_tree = struct('k', 5); + case 'ec_tree_homologs' + stages = [stage('select', own, 1), stage('combine', {'ec_tree', 'homologs'}, 4), ... + stage('combine', {'okp'}, 4)]; + sources.brenda = struct('aggregation', 'median'); + sources.ec_tree = struct('k', 5); + case 'ec_tree_okp' + stages = [stage('select', own, 1), stage('combine', {'ec_tree', 'homologs', 'okp'}, 4), ... + stage('combine', {'okp'}, 4)]; + sources.brenda = struct('aggregation', 'median'); + sources.ec_tree = struct('k', 5); + case 'okp' + stages = [stage('select', {'custom'}, 4), stage('combine', {'okp'}, 4)]; + case 'gecko_median' + stages = stage('select', order, 4); + sources.brenda = struct('aggregation', 'median'); + case 'gecko_classic' + stages = stage('select', order, 6); + sources.brenda = struct('aggregation', 'max'); + otherwise + error('kcatAssignment:config', 'Unknown kcat assignment preset "%s". Presets: %s.', ... + preset, 'brenda_ec_tree, ec_tree_homologs, ec_tree_okp, okp, gecko_median, gecko_classic') +end +end + +function stage = readStage(s) +stage.action = getOr(s, 'action', 'select'); +if ~any(strcmp(stage.action, {'select', 'combine'})) + error('kcatAssignment:config', ['Unknown stage action "%s"; this GECKO version knows ' ... + '"select" and "combine".'], stage.action) +end +sources = getOr(s, 'sources', {}); +if ~iscell(sources) + error('kcatAssignment:config', 'The sources of a [[kcat_assignment.stage]] must be a list of source names.') +end +if isempty(sources) + error('kcatAssignment:config', 'A [[kcat_assignment.stage]] needs sources.') +end +stage.sources = sources(:)'; +stage.criteria = getOr(s, 'criteria', 'max'); +if ~((ischar(stage.criteria) || isstring(stage.criteria)) && ... + any(strcmp(stage.criteria, {'max','min','median','mean'}))) + error('kcatAssignment:config', 'Unknown criteria of a [[kcat_assignment.stage]]; criteria: max, min, median, mean.') +end +stage.criteria = char(stage.criteria); +stage.topOriginLimit = getOr(s, 'top_origin_limit', 4); +stage.bottomOriginLimit = getOr(s, 'bottom_origin_limit', 6); +stage.wildcardLimit = getOr(s, 'wildcard_limit', 3); +end + +function v = getOr(s, field, default) +v = default; +if isstruct(s) && isfield(s, field) && ~isempty(s.(field)) + v = s.(field); +end +end diff --git a/src/gather_kcats/kcatsFromBrenda.m b/src/gather_kcats/kcatsFromBrenda.m new file mode 100644 index 00000000..5df57419 --- /dev/null +++ b/src/gather_kcats/kcatsFromBrenda.m @@ -0,0 +1,148 @@ +function kcatList = kcatsFromBrenda(model, varargin) +% kcatsFromBrenda Gather kcats from BRENDA and keep them as a source file. +% +% Matches the model's EC numbers and substrates to BRENDA by fuzzy +% matching (see fuzzyKcatMatching), and writes the result to +% data/kcats/brenda.tsv in the project folder (see saveKcatSource). The +% matching runs locally on the BRENDA files of GECKO. +% +% Parameters +% ---------- +% model : struct +% an ecModel in GECKO 3 format (with ecModel.ec structure), with EC +% numbers (getECfromDatabase or getECfromGEM). +% +% Name-Value Arguments +% -------------------- +% aggregation : char +% which BRENDA value per EC number, substrate and organism is used: +% 'max' or 'median' (default: params.kcatAggregation of the model +% adapter, or 'max'). +% forceWClvl : double +% number of extra levels, from the right, replaced by a wildcard in the +% EC numbers (on top of any wildcard already in the code; default 0). +% ecRxns : logical or double +% for which model.ec.rxns kcats are gathered (default: all). A logical +% vector or indices of model.ec.rxns, see fuzzyKcatMatching; [] selects +% all reactions and any other empty selection is an error. +% save : logical +% write the source file (default true). +% saveAs : char +% name of the source file, without .tsv (default 'brenda'). With +% ecRxns, the file then only holds those reactions. +% modelAdapter : ModelAdapter +% a loaded model adapter (default: the current default model adapter). +% +% Returns +% ------- +% kcatList : struct +% the kcat values, as returned by fuzzyKcatMatching. +% +% Examples +% -------- +% kcatsFromBrenda(ecModel); +% kcatList = kcatsFromBrenda(ecModel, 'aggregation', 'median'); +% +% See also +% -------- +% fuzzyKcatMatching, kcatsFromDLKcat, kcatsFromOKP, saveKcatSource, loadKcatSource + +checkOptions(varargin, {'aggregation','forceWClvl','ecRxns','save','saveAs','modelAdapter'}, 'kcatsFromBrenda'); +p = parseGECKOargs(varargin, { ... + 'aggregation', []; ... + 'forceWClvl', 0; ... + 'ecRxns', []; ... + 'save', true; ... + 'saveAs', 'brenda'; ... + 'modelAdapter', []}); +modelAdapter = p.modelAdapter; +if isempty(modelAdapter) + modelAdapter = ModelAdapterManager.getDefault(); + if isempty(modelAdapter) + error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.') + end +end +aggregation = resolveKcatAggregation(p.aggregation, modelAdapter); +if isSubset(p.ecRxns) && countSelected(p.ecRxns) == 0 + error('kcatsFromBrenda:emptySubset', ... + 'ecRxns selects no reactions; leave it out to gather for all reactions.'); +end +if p.save + file = fullfile(modelAdapter.params.path, 'data', 'kcats', [char(p.saveAs) '.tsv']); + warnSubset(p.ecRxns, numel(model.ec.rxns), file); +end + +kcatList = fuzzyKcatMatching(model, 'ecRxns', p.ecRxns, 'modelAdapter', modelAdapter, ... + 'forceWClvl', p.forceWClvl, 'kcatAggregation', aggregation); + +if p.save + parameters = struct('aggregation', aggregation, 'force_wildcard_level', p.forceWClvl); + if isSubset(p.ecRxns) + parameters.ec_rxns = numel(kcatList.rxns); + end + saveKcatSource(model, kcatList, p.saveAs, 'modelAdapter', modelAdapter, ... + 'generator', 'kcatsFromBrenda', 'parameters', parameters, ... + 'data', brendaRelease(modelAdapter)); + fprintf('BRENDA kcats for %d reactions written to %s\n', sum(kcatList.kcats > 0), file); +end +end + +function release = brendaRelease(modelAdapter) +% The release line at the top of kcat.tsv, e.g. 'BRENDA release 2026.1'. +release = ''; +file = fullfile(modelAdapter.getBrendaDBFolder(), 'kcat.tsv'); +fid = fopen(file, 'r'); +if fid < 0 + return +end +line = fgetl(fid); +fclose(fid); +tok = regexp(line, '^#\s*(BRENDA release [^ ]+)', 'tokens', 'once'); +if ~isempty(tok) + release = tok{1}; +end +end + +function tf = isSubset(ecRxns) +% [] selects all reactions; any other value selects the reactions it names. +tf = ~(isnumeric(ecRxns) && isequal(size(ecRxns),[0 0])); +end + +function n = countSelected(ecRxns) +if islogical(ecRxns) + n = sum(ecRxns); +else + n = numel(ecRxns); +end +end + +function n = countRxns(ecRxns) +if islogical(ecRxns) + n = sum(ecRxns); +else + n = numel(unique(ecRxns)); +end +end + +function warnSubset(ecRxns, nRxns, file) +% A subset written under the default name replaces the full file. +if isSubset(ecRxns) && countRxns(ecRxns) < nRxns && isfile(file) + printOrange(sprintf(['%s is replaced by kcats for %d reactions only. Give saveAs ' ... + 'to keep it.\n'], file, countRxns(ecRxns))); +end +end + +function checkOptions(args, names, functionName) +% Options are name-value pairs with known names, so a misspelled option is +% an error instead of being taken as a positional argument. +id = [functionName ':arguments']; +given = args(1:2:end); +if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given)) + error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', ')) +end +unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names); +if ~isempty(unknown) + error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ... + strjoin(names, ', ')) +end +end diff --git a/src/gather_kcats/kcatsFromDLKcat.m b/src/gather_kcats/kcatsFromDLKcat.m new file mode 100644 index 00000000..4608e3d2 --- /dev/null +++ b/src/gather_kcats/kcatsFromDLKcat.m @@ -0,0 +1,145 @@ +function kcatList = kcatsFromDLKcat(model, varargin) +% kcatsFromDLKcat Gather kcats from DLKcat and keep them as a source file. +% +% Predicts kcats with DLKcat and writes them to data/kcats/dlkcat.tsv in +% the project folder (see saveKcatSource). With 'run', true it writes the +% DLKcat input (writeDLKcatInput) and runs DLKcat through its Docker image +% (runDLKcat), which needs Docker; otherwise it reads the output of an +% earlier run (readDLKcatOutput). A run records how many reactions it +% covered in data/DLKcat_run.txt, so that the source file says so also when +% the output is read later. +% +% Parameters +% ---------- +% model : struct +% an ecModel in GECKO 3 format (with ecModel.ec structure), with +% metabolite SMILES (findMetSmiles) and protein sequences. +% +% Name-Value Arguments +% -------------------- +% run : logical +% write the input and run DLKcat; false reads the existing output in +% data/DLKcat.tsv (default false). +% ecRxns : logical +% for which model.ec.rxns DLKcat is run (default: all). Only used with +% 'run', true. +% save : logical +% write the source file (default true). +% saveAs : char +% name of the source file, without .tsv (default 'dlkcat'). +% modelAdapter : ModelAdapter +% a loaded model adapter (default: the current default model adapter). +% +% Returns +% ------- +% kcatList : struct +% the kcat values, as returned by readDLKcatOutput. +% +% Examples +% -------- +% kcatsFromDLKcat(ecModel, 'run', true); +% kcatList = kcatsFromDLKcat(ecModel); +% +% See also +% -------- +% writeDLKcatInput, runDLKcat, readDLKcatOutput, kcatsFromBrenda, saveKcatSource + +checkOptions(varargin, {'run','ecRxns','save','saveAs','modelAdapter'}, 'kcatsFromDLKcat'); +p = parseGECKOargs(varargin, { ... + 'run', false; ... + 'ecRxns', []; ... + 'save', true; ... + 'saveAs', 'dlkcat'; ... + 'modelAdapter', []}); +modelAdapter = p.modelAdapter; +if isempty(modelAdapter) + modelAdapter = ModelAdapterManager.getDefault(); + if isempty(modelAdapter) + error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.') + end +end +if ~p.run && ~isempty(p.ecRxns) + error('kcatsFromDLKcat:ecRxns', ['ecRxns selects the reactions DLKcat is run for, so ' ... + 'it needs ''run'', true.']) +end +if p.save + file = fullfile(modelAdapter.params.path, 'data', 'kcats', [char(p.saveAs) '.tsv']); + if p.run + warnSubset(p.ecRxns, numel(model.ec.rxns), file); + end +end + +runFile = fullfile(modelAdapter.params.path, 'data', 'DLKcat_run.txt'); +if p.run + % As runDLKcat: on macOS, MATLAB started from the launcher may not + % have Docker on its path. + if ismac + setenv('PATH', strcat('/usr/local/bin', ':', getenv("PATH"))); + end + [status, ~] = system('docker --version'); + if status ~= 0 + error('kcatsFromDLKcat:noDocker', ['DLKcat runs in a Docker image, but Docker was ' ... + 'not found. Install it from https://www.docker.com, or call kcatsFromDLKcat ' ... + 'without ''run'' to read an earlier DLKcat output.']) + end + writeDLKcatInput(model, 'ecRxns', p.ecRxns, 'modelAdapter', modelAdapter, 'overwrite', true); + runDLKcat('modelAdapter', modelAdapter); + fid = fopen(runFile, 'w'); + if ~isempty(p.ecRxns) + fprintf(fid, 'ecRxns: %d\n', countRxns(p.ecRxns)); + end + fclose(fid); +else + outFile = fullfile(modelAdapter.params.path, 'data', 'DLKcat.tsv'); + if ~isfile(outFile) + error('kcatsFromDLKcat:noOutput', ['No DLKcat output at %s. Run ' ... + 'kcatsFromDLKcat(model, ''run'', true) first.'], outFile) + end +end +kcatList = readDLKcatOutput(model, 'modelAdapter', modelAdapter); + +if p.save + parameters = struct('run', logical(p.run)); + if isfile(runFile) + tok = regexp(fileread(runFile), 'ecRxns:\s*(\d+)', 'tokens', 'once'); + if ~isempty(tok) + parameters.ec_rxns = str2double(tok{1}); + end + end + saveKcatSource(model, kcatList, p.saveAs, 'modelAdapter', modelAdapter, ... + 'generator', 'kcatsFromDLKcat', 'parameters', parameters); + fprintf('DLKcat kcats for %d reactions written to %s\n', ... + numel(unique(kcatList.rxns(kcatList.kcats > 0))), file); +end +end + +function n = countRxns(ecRxns) +if islogical(ecRxns) + n = sum(ecRxns); +else + n = numel(unique(ecRxns)); +end +end + +function warnSubset(ecRxns, nRxns, file) +% A subset written under the default name replaces the full file. +if ~isempty(ecRxns) && countRxns(ecRxns) < nRxns && isfile(file) + printOrange(sprintf(['%s is replaced by kcats for %d reactions only. Give saveAs ' ... + 'to keep it.\n'], file, countRxns(ecRxns))); +end +end + +function checkOptions(args, names, functionName) +% Options are name-value pairs with known names, so a misspelled option is +% an error instead of being taken as a positional argument. +id = [functionName ':arguments']; +given = args(1:2:end); +if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given)) + error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', ')) +end +unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names); +if ~isempty(unknown) + error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ... + strjoin(names, ', ')) +end +end diff --git a/src/gather_kcats/kcatsFromECTree.m b/src/gather_kcats/kcatsFromECTree.m new file mode 100644 index 00000000..e14828a9 --- /dev/null +++ b/src/gather_kcats/kcatsFromECTree.m @@ -0,0 +1,141 @@ +function kcatList = kcatsFromECTree(model, varargin) +% kcatsFromECTree Estimate kcats from the EC tree and keep them as a source file. +% +% Each reaction gets the median kcat of all wild-type BRENDA measurements +% of its EC number, from any organism and substrate, shrunk toward the +% median of the EC's 3-digit and 2-digit classes with weight n / (n + k) +% for n measurements (see ecTreeEstimate). A reaction with several EC +% numbers uses the one with most measurements. Reactions without an EC +% number, or whose EC classes have no measurements, get no value. The +% result is written to data/kcats/ec_tree.tsv in the project folder (see +% saveKcatSource). +% +% Parameters +% ---------- +% model : struct +% an ecModel in GECKO 3 format (with ecModel.ec structure), with EC +% numbers (getECfromDatabase or getECfromGEM). +% +% Name-Value Arguments +% -------------------- +% k : double +% shrinkage constant (default 5): the number of measurements at which +% an EC's own median and its class count equally. +% ecRxns : logical or double +% for which model.ec.rxns kcats are estimated, as a logical vector or as +% indices (default: all). A reaction named more than once gives one +% row. An empty ecRxns given explicitly selects no reaction. +% measurements : struct +% BRENDA measurement table (default: loadBrendaMeasurements with the +% model adapter). +% save : logical +% write the source file (default true). +% saveAs : char +% name of the source file, without .tsv (default 'ec_tree'). With +% ecRxns, the file then only holds those reactions. +% modelAdapter : ModelAdapter +% a loaded model adapter (default: the current default model adapter). +% +% Returns +% ------- +% kcatList : struct +% the kcat values, with fields source, rxns, eccodes, kcats and detail +% (the number of measurements of the EC, n, and the deepest EC level +% with measurements, depth). +% +% Examples +% -------- +% kcatsFromECTree(ecModel); +% kcatList = kcatsFromECTree(ecModel, 'k', 10, 'save', false); +% +% See also +% -------- +% ecTreeEstimate, loadBrendaMeasurements, kcatsFromBrenda, saveKcatSource, assignKcats + +checkOptions(varargin, {'k','ecRxns','measurements','save','saveAs','modelAdapter'}, 'kcatsFromECTree'); +p = parseGECKOargs(varargin, { ... + 'k', 5; ... + 'ecRxns', []; ... + 'measurements', []; ... + 'save', true; ... + 'saveAs', 'ec_tree'; ... + 'modelAdapter', []}); +modelAdapter = p.modelAdapter; +hasSubset = any(strcmp(cellfun(@char, varargin(1:2:end), 'UniformOutput', false), 'ecRxns')); +if isempty(modelAdapter) + modelAdapter = ModelAdapterManager.getDefault(); + if isempty(modelAdapter) + error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.') + end +end +if ~isfield(model.ec, 'eccodes') + error('No EC codes defined in model.ec.eccodes. First run getECfromGEM() and/or getECfromDatabase().') +end +if p.save + file = fullfile(modelAdapter.params.path, 'data', 'kcats', [char(p.saveAs) '.tsv']); + warnSubset(p.ecRxns, hasSubset, numel(model.ec.rxns), file); +end +measurements = p.measurements; +if isempty(measurements) + measurements = loadBrendaMeasurements('modelAdapter', modelAdapter); +end + +idx = (1:numel(model.ec.rxns))'; +if hasSubset + selected = false(numel(idx), 1); + selected(p.ecRxns(:)) = true; + idx = idx(selected); +end +eccodes = model.ec.eccodes(idx); +eccodes(cellfun(@(e) ~ischar(e) && ~isstring(e), eccodes)) = {''}; +[values, n, depth, ecUsed] = ecTreeEstimate(eccodes, measurements, p.k); +found = depth > 0; +idx = idx(found); +kcatList.source = 'ec_tree'; +kcatList.rxns = model.ec.rxns(idx); +kcatList.eccodes = ecUsed(found); +kcatList.kcats = 10 .^ values(found); +kcatList.detail = cellstr("n=" + string(n(found)) + "; depth=" + string(depth(found))); + +if p.save + parameters = struct('k', p.k); + if hasSubset + parameters.ec_rxns = countRxns(p.ecRxns); + end + saveKcatSource(model, kcatList, p.saveAs, 'modelAdapter', modelAdapter, ... + 'generator', 'kcatsFromECTree', 'parameters', parameters, ... + 'data', measurements.release); + fprintf('EC-tree kcats for %d reactions written to %s\n', numel(kcatList.rxns), file); +end +end + +function n = countRxns(ecRxns) +if islogical(ecRxns) + n = sum(ecRxns); +else + n = numel(unique(ecRxns)); +end +end + +function warnSubset(ecRxns, hasSubset, nRxns, file) +% A subset written under the default name replaces the full file. +if hasSubset && countRxns(ecRxns) < nRxns && isfile(file) + printOrange(sprintf(['%s is replaced by kcats for %d reactions only. Give saveAs ' ... + 'to keep it.\n'], file, countRxns(ecRxns))); +end +end + +function checkOptions(args, names, functionName) +% Options are name-value pairs with known names, so a misspelled option is +% an error instead of being taken as a positional argument. +id = [functionName ':arguments']; +given = args(1:2:end); +if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given)) + error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', ')) +end +unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names); +if ~isempty(unknown) + error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ... + strjoin(names, ', ')) +end +end diff --git a/src/gather_kcats/kcatsFromHomologs.m b/src/gather_kcats/kcatsFromHomologs.m new file mode 100644 index 00000000..9cee5936 --- /dev/null +++ b/src/gather_kcats/kcatsFromHomologs.m @@ -0,0 +1,299 @@ +function kcatList = kcatsFromHomologs(model, varargin) +% kcatsFromHomologs Estimate kcats from measured homologs and keep them as a source file. +% +% For each reaction, enzyme and substrate (the substrates DLKcat would use, +% see extractEnzymeSubstratePairs), the enzyme's sequence is searched with +% DIAMOND against the sequences of the BRENDA measurements (at least 40% +% identity, 80% coverage of both sequences). Each homolog measured on the +% same substrate (same InChIKey, without the protonation flag) contributes +% the median of its measurements; the estimate is the mean of the k most +% identical such homologs, weighted by identity. Homologs at 95% identity or +% more are measurements of (nearly) the same protein: when there are any, +% the estimate is the median of those alone. For an enzyme complex the +% estimate is the median over its subunits. Model metabolites are matched to +% InChIKeys through substrates.tsv of the BRENDA files: their ChEBI +% annotations, then MetaNetX annotations (model.metMiriams), then their +% names. Reactions without a homolog measured on one of their substrates get +% no value. The result is written to data/kcats/homologs.tsv (see +% saveKcatSource). DIAMOND is RAVEN's (getDiamond; downloaded when +% missing). geckopy has the same (kcats_from_homologs). +% +% Parameters +% ---------- +% model : struct +% an ecModel in GECKO 3 format (with ecModel.ec structure), with enzyme +% sequences (model.ec.sequence). +% +% Name-Value Arguments +% -------------------- +% k : double +% the number of most identical homologs averaged (default 10). +% minIdentity : double +% DIAMOND identity threshold, as a fraction (default 0.4). +% coverage : double +% DIAMOND coverage threshold of both sequences, as a fraction (default 0.8). +% threads : double +% DIAMOND threads (default: DIAMOND's). +% save : logical +% write the source file (default true). +% saveAs : char +% name of the source file, without .tsv (default 'homologs'). +% modelAdapter : ModelAdapter +% a loaded model adapter (default: the current default model adapter). +% +% Returns +% ------- +% kcatList : struct +% the kcat values, with fields source, rxns, substrates, kcats and +% detail (the identity of the nearest homolog, identity, and the number +% of homologs used, n). +% +% Examples +% -------- +% kcatsFromHomologs(ecModel); +% +% See also +% -------- +% kcatsFromECTree, extractEnzymeSubstratePairs, saveKcatSource, collectKcats + +checkOptions(varargin, {'k','minIdentity','coverage','threads','save','saveAs','modelAdapter'}, 'kcatsFromHomologs'); +p = parseGECKOargs(varargin, { ... + 'k', 10; ... + 'minIdentity', 0.4; ... + 'coverage', 0.8; ... + 'threads', []; ... + 'save', true; ... + 'saveAs', 'homologs'; ... + 'modelAdapter', []}); +modelAdapter = p.modelAdapter; +if isempty(modelAdapter) + modelAdapter = ModelAdapterManager.getDefault(); + if isempty(modelAdapter) + error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.') + end +end + +measurements = loadBrendaMeasurements('folder', fileparts(brendaFile(modelAdapter, 'measurements.tsv'))); +substrates = readSubstrates(brendaFile(modelAdapter, 'substrates.tsv')); +sequencesFile = brendaFile(modelAdapter, 'sequences.fasta'); + +pairs = extractEnzymeSubstratePairs(model, 'modelAdapter', modelAdapter); +iks = metaboliteInchikeys(model, substrates); +pairIk = iks(pairs.met); +seqs = model.ec.sequence(pairs.protein); +keep = ~cellfun(@isempty, pairIk) & ~cellfun(@isempty, seqs); +rxnIdx = pairs.ecRxn(keep); metIdx = pairs.met(keep); pairIk = pairIk(keep); seqs = seqs(keep); + +kcatList.source = 'homologs'; +kcatList.rxns = cell(0, 1); +kcatList.substrates = cell(0, 1); +kcatList.kcats = zeros(0, 1); +kcatList.detail = cell(0, 1); +if ~isempty(seqs) + [useqs, ~, seqNo] = unique(seqs, 'stable'); + queryIds = cellstr(compose('q%d', (0:numel(useqs)-1)')); + hits = diamondHits(queryIds, useqs, sequencesFile, p.minIdentity, p.coverage, p.threads); + % Median log10 kcat per measured sequence and substrate. + hasSeq = ~cellfun(@isempty, measurements.seq_id) & ~cellfun(@isempty, measurements.substrate_inchikey); + key = strcat(measurements.seq_id(hasSeq), '|', cellfun(@(s) s(1:min(25, end)), ... + measurements.substrate_inchikey(hasSeq), 'UniformOutput', false)); + [ukey, ~, g] = unique(key); + med = containers.Map(ukey, num2cell(accumarray(g, measurements.log10kcat(hasSeq), [], @median))); + % Estimate per enzyme sequence and substrate. + [up, ~, pairNo] = unique(strcat(queryIds(seqNo), '|', pairIk), 'stable'); + est = nan(numel(up), 1); best = nan(numel(up), 1); nHom = zeros(numel(up), 1); + for u = 1:numel(up) + parts = strsplit(up{u}, '|'); + rows = find(strcmp(hits.query, parts{1})); + found = zeros(0, 2); + for r = rows(:)' + mk = [hits.target{r} '|' parts{2}]; + if isKey(med, mk) + found(end+1, :) = [hits.identity(r), med(mk)]; %#ok + end + end + if isempty(found) + continue + end + exact = found(found(:, 1) >= 0.95, 2); + best(u) = found(1, 1); + if ~isempty(exact) + est(u) = median(exact); + nHom(u) = numel(exact); + else + found = found(1:min(p.k, end), :); + est(u) = sum(found(:, 1) .* found(:, 2)) / sum(found(:, 1)); + nHom(u) = size(found, 1); + end + end + % One row per reaction and substrate: the median over its enzymes. + [ur, ~, rs] = unique(strcat(model.ec.rxns(rxnIdx), '|', model.metNames(metIdx)), 'stable'); + for r = 1:numel(ur) + members = unique(pairNo(rs == r)); + members = members(~isnan(est(members))); + if isempty(members) + continue + end + [~, b] = max(best(members)); + first = find(rs == r, 1); + kcatList.rxns{end+1, 1} = model.ec.rxns{rxnIdx(first)}; + kcatList.substrates{end+1, 1} = model.metNames{metIdx(first)}; + kcatList.kcats(end+1, 1) = 10 ^ median(est(members)); + kcatList.detail{end+1, 1} = sprintf('identity=%.3f; n=%d', best(members(b)), nHom(members(b))); + end +end + +if p.save + parameters = struct('coverage', p.coverage, 'k', p.k, 'min_identity', p.minIdentity); + file = saveKcatSource(model, kcatList, p.saveAs, 'modelAdapter', modelAdapter, ... + 'generator', 'kcatsFromHomologs', 'parameters', parameters, 'data', measurements.release); + fprintf('Homolog kcats for %d reactions written to %s\n', numel(unique(kcatList.rxns)), file); +end +end + +function file = brendaFile(modelAdapter, name) +% A file of the adapter's BRENDA folder, or of GECKO's BRENDA release. +file = fullfile(modelAdapter.getBrendaDBFolder(), name); +if ~isfile(file) + file = fullfile(fetchBrendaAsset({name}), name); +end +end + +function s = readSubstrates(file) +fid = fopen(file, 'r', 'n', 'UTF-8'); +c = textscan(fid, '%s %s %s', 'Delimiter', '\t', 'CommentStyle', '#', 'HeaderLines', 0); +fclose(fid); +header = strcmp(c{1}, 'inchikey'); +s.inchikey = c{1}(~header); s.kind = c{2}(~header); s.value = c{3}(~header); +end + +function iks = metaboliteInchikeys(model, substrates) +% InChIKey (first 25 characters) per model metabolite, '' when unknown: +% from its ChEBI annotations, then its MetaNetX annotations, then its name. +maps = struct(); +for kind = {'chebi', 'metanetx', 'name'} + k = strcmp(substrates.kind, kind{1}); + [values, first] = unique(substrates.value(k), 'stable'); + ik = substrates.inchikey(k); + maps.(kind{1}) = containers.Map('KeyType', 'char', 'ValueType', 'char'); + if ~isempty(values) + maps.(kind{1}) = containers.Map(values, ik(first)); + end +end +iks = repmat({''}, numel(model.mets), 1); +for i = 1:numel(model.mets) + for pair = {{'chebi', 'chebi'}, {'metanetx', 'metanetx.chemical'}} + kind = pair{1}{1}; + for v = annotations(model, i, pair{1}{2}) + if isKey(maps.(kind), v{1}) + iks{i} = maps.(kind)(v{1}); + break + end + end + if ~isempty(iks{i}) + break + end + end + if isempty(iks{i}) && isKey(maps.name, compactName(model.metNames{i})) + iks{i} = maps.name(compactName(model.metNames{i})); + end +end +end + +function values = annotations(model, i, key) +% The identifiers of one annotation of a metabolite, without their prefix. +values = {}; +if ~isfield(model, 'metMiriams') || numel(model.metMiriams) < i || ~isstruct(model.metMiriams{i}) + return +end +m = model.metMiriams{i}; +hit = strcmpi(m.name, key); +values = regexprep(strtrim(m.value(hit)), '^.*:', ''); +values = values(:)'; +end + +function s = compactName(name) +% A name as the compact keys of substrates.tsv: without markup, Greek letters +% spelled out, accents dropped, lower case, only letters, digits and +. +s = regexprep(char(name), '<[^>]+>', ''); +s = strrep(strrep(strrep(strrep(strrep(s, '&', '&'), '<', '<'), '>', '>'), '"', '"'), ''', ''''); +greek = {char(945), 'alpha'; char(946), 'beta'; char(947), 'gamma'; char(948), 'delta'; char(949), 'epsilon'; ... + char(969), 'omega'; char(954), 'kappa'; char(955), 'lambda'; char(956), 'mu'; char(968), 'psi'; ... + char(958), 'xi'; char(950), 'zeta'}; +for g = 1:size(greek, 1) + s = strrep(strrep(s, greek{g, 1}, greek{g, 2}), upper(greek{g, 1}), greek{g, 2}); +end +s = char(javaMethod('normalize', 'java.text.Normalizer', java.lang.String(s), ... + javaMethod('valueOf', 'java.text.Normalizer$Form', 'NFKD'))); +s = s(double(s) < 128); +s = regexprep(lower(s), '[^a-z0-9+]', ''); +end + +function hits = diamondHits(ids, sequences, targetFasta, minIdentity, coverage, threads) +% DIAMOND hits of the query sequences against a FASTA file: query, target, +% identity (a fraction), best identity first per query, then by target. +ravenPath = findRAVENroot(); +if ismac + binEnd = '.mac'; +elseif ispc + binEnd = '.exe'; +else + binEnd = ''; +end +exe = fullfile(ravenPath, 'src', 'external', 'diamond', ['diamond' binEnd]); +if ~isfile(exe) + downloadRavenBinaries({'diamond'}); +end +tmp = tempname; mkdir(tmp); +cleanup = onCleanup(@() rmdir(tmp, 's')); +fid = fopen(fullfile(tmp, 'queries.fasta'), 'w'); +entries = [cellstr(ids(:))'; cellstr(sequences(:))']; +fprintf(fid, '>%s\n%s\n', entries{:}); +fclose(fid); +run = @(args) system(['"' exe '" ' args]); +[status, out] = run(sprintf('makedb --in "%s" --db "%s" --quiet', targetFasta, fullfile(tmp, 'targets'))); +if status ~= 0 + error('kcatsFromHomologs:diamond', 'DIAMOND makedb failed: %s', out) +end +args = sprintf(['blastp --query "%s" --db "%s" --out "%s" --ultra-sensitive --id %g --query-cover %g ' ... + '--subject-cover %g --evalue 0.001 --max-target-seqs 0 --outfmt 6 qseqid sseqid pident --quiet'], ... + fullfile(tmp, 'queries.fasta'), fullfile(tmp, 'targets'), fullfile(tmp, 'hits.tsv'), ... + 100 * minIdentity, 100 * coverage, 100 * coverage); +if ~isempty(threads) + args = sprintf('%s --threads %d', args, threads); +end +[status, out] = run(args); +if status ~= 0 + error('kcatsFromHomologs:diamond', 'DIAMOND blastp failed: %s', out) +end +fid = fopen(fullfile(tmp, 'hits.tsv'), 'r'); +c = textscan(fid, '%s %s %f', 'Delimiter', '\t'); +fclose(fid); +q = c{1}; t = c{2}; ident = c{3} / 100; +% Best identity per query and target. +[pairKeys, ~, g] = unique(strcat(q, '|', t)); +ident = accumarray(g, ident, [], @max); +parts = split(pairKeys, '|'); +if isempty(pairKeys) + parts = cell(0, 2); +end +parts = reshape(parts, [], 2); +T = table(parts(:, 1), parts(:, 2), ident, 'VariableNames', {'query', 'target', 'identity'}); +T = sortrows(T, {'query', 'identity', 'target'}, {'ascend', 'descend', 'ascend'}); +hits = struct('query', {T.query}, 'target', {T.target}, 'identity', T.identity); +end + +function checkOptions(args, names, functionName) +% Options are name-value pairs with known names, so a misspelled option is +% an error instead of being taken as a positional argument. +id = [functionName ':arguments']; +given = args(1:2:end); +if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given)) + error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', ')) +end +unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names); +if ~isempty(unknown) + error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ... + strjoin(names, ', ')) +end +end diff --git a/src/gather_kcats/kcatsFromOKP.m b/src/gather_kcats/kcatsFromOKP.m new file mode 100644 index 00000000..9902ffde --- /dev/null +++ b/src/gather_kcats/kcatsFromOKP.m @@ -0,0 +1,254 @@ +function [kcatList, done] = kcatsFromOKP(model, varargin) +% kcatsFromOKP Gather kcats from OpenKineticsPredictor and keep them as a source file. +% +% Predicts kcats with one OpenKineticsPredictor (OKP) method and writes +% them to data/kcats/okp_.tsv in the project folder (see +% saveKcatSource). OKP is a web service with a job queue, so this function +% can be called repeatedly: +% +% - without a job for this method, it submits one +% (submitOpenKineticsPredictor); +% - with a job, it fetches the result (fetchOpenKineticsPredictor). When +% the job is done the file is written; otherwise it reports the job's +% status and writes nothing. +% +% Each method keeps its own job in data/OKP_job_.txt and its own +% result in data/OKP_output_.csv, so jobs of several methods can +% run at the same time. The job file records which job the stored result +% came from; useStored only uses a result of the current job. An API key +% is needed (see resolveOkpApiKey). +% +% Parameters +% ---------- +% model : struct +% an ecModel in GECKO 3 format (with ecModel.ec structure), with +% metabolite SMILES (findMetSmiles) and protein sequences. +% +% Name-Value Arguments +% -------------------- +% method : char +% OKP method, e.g. 'CataPro', 'CatPred', 'CatRange', 'DLKcat', +% 'EITLEM', 'KinForm-H', 'KinForm-L', 'OmniESI', 'TurNup', 'UniKP' +% (default: params.okp.method of the model adapter, or 'CataPro'). +% wait : logical +% wait until the job is done (default false). +% resubmit : logical +% submit a new job even if one exists for this method; its earlier +% result is removed (default false). +% useStored : logical +% read the stored result of this method's job, without contacting OKP +% (default false). +% ecRxns : logical +% for which model.ec.rxns kcats are predicted (default: all). Only +% used when a job is submitted. +% save : logical +% write the source file (default true). +% saveAs : char +% name of the source file, without .tsv (default 'okp_', in +% lower case, with other characters than letters and digits as '_'). +% modelAdapter : ModelAdapter +% a loaded model adapter (default: the current default model adapter). +% +% Returns +% ------- +% kcatList : struct +% the kcat values, as returned by readOpenKineticsPredictorOutput; +% empty while the job is not done. +% done : logical +% whether the result was available. +% +% Examples +% -------- +% kcatsFromOKP(ecModel, 'method', 'CataPro'); % submits +% kcatsFromOKP(ecModel, 'method', 'CataPro'); % later: fetches and writes +% kcatsFromOKP(ecModel, 'method', 'UniKP', 'wait', true); +% +% See also +% -------- +% submitOpenKineticsPredictor, fetchOpenKineticsPredictor, kcatsFromBrenda, saveKcatSource + +checkOptions(varargin, {'method','wait','resubmit','useStored','ecRxns','save','saveAs','modelAdapter'}, 'kcatsFromOKP'); +p = parseGECKOargs(varargin, { ... + 'method', []; ... + 'wait', false; ... + 'resubmit', false; ... + 'useStored', false; ... + 'ecRxns', []; ... + 'save', true; ... + 'saveAs', []; ... + 'modelAdapter', []}); +modelAdapter = p.modelAdapter; +if isempty(modelAdapter) + modelAdapter = ModelAdapterManager.getDefault(); + if isempty(modelAdapter) + error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.') + end +end +params = modelAdapter.params; +method = char(p.method); +if isempty(method) + if isfield(params, 'okp') && isfield(params.okp, 'method') && ~isempty(params.okp.method) + method = char(params.okp.method); + else + method = 'CataPro'; + end +end +if any(strcmp(method, {'CatPred', 'TurNup'})) + error('kcatsFromOKP:method', ['%s reads whole reactions (its substrate set, and products ' ... + 'for TurNup); kcatsFromOKP submits enzyme-substrate pairs only.'], method) +end +tag = lower(regexprep(method, '[^A-Za-z0-9]+', '_')); +dataDir = fullfile(params.path, 'data'); +jobFile = fullfile(dataDir, ['OKP_job_' tag '.txt']); +outFile = fullfile(dataDir, ['OKP_output_' tag '.csv']); +name = char(p.saveAs); +if isempty(name) + name = ['okp_' tag]; +end +job = readJobFile(jobFile); +submitting = ~p.useStored && (p.resubmit || ~isfield(job, 'jobId')); +if ~isempty(p.ecRxns) && ~submitting + error('kcatsFromOKP:ecRxns', ['ecRxns selects the reactions of a new job, but this call ' ... + 'submits none (a job for %s exists; use ''resubmit'', true for a new one).'], method) +end +if p.save + file = fullfile(modelAdapter.params.path, 'data', 'kcats', [char(name) '.tsv']); + if submitting + warnSubset(p.ecRxns, numel(model.ec.rxns), file); + end +end + +if p.useStored + if ~isfield(job, 'jobId') + adoptSharedResult(model, modelAdapter, dataDir, method, jobFile, outFile); + job = readJobFile(jobFile); + end + if ~isfile(outFile) || ~isfield(job, 'resultOf') || ~strcmp(job.resultOf, job.jobId) + error('kcatsFromOKP:noStored', ['No stored result of the current %s job (%s). Call ' ... + 'kcatsFromOKP without ''useStored'' to fetch it.'], method, jobFile) + end + kcatList = readOpenKineticsPredictorOutput(model, 'outFile', outFile, 'modelAdapter', modelAdapter); + done = true; +else + if submitting + if isfile(outFile) + delete(outFile); + end + jobId = submitOpenKineticsPredictor(model, 'method', method, 'ecRxns', p.ecRxns, ... + 'overwrite', true, 'modelAdapter', modelAdapter); + job = struct('jobId', jobId, 'method', method, 'submittedAt', ... + char(datetime('now', 'TimeZone', 'UTC', 'Format', 'yyyy-MM-dd''T''HH:mm:ss''Z'''))); + if ~isempty(p.ecRxns) + job.ecRxns = sprintf('%d', countRxns(p.ecRxns)); + end + writeJobFile(jobFile, job); + end + [done, kcatList] = fetchOpenKineticsPredictor(model, 'jobId', job.jobId, 'wait', p.wait, ... + 'outFile', outFile, 'modelAdapter', modelAdapter); + if done + job.resultOf = job.jobId; + writeJobFile(jobFile, job); + end +end + +if ~done + fprintf('Call kcatsFromOKP(model, ''method'', ''%s'') again later to collect the result.\n', method); + return +end +if p.save + parameters = struct('method', method); + if isfield(job, 'ecRxns') + parameters.ec_rxns = str2double(job.ecRxns); + end + if isfield(kcatList, 'similarity') + kcatList.detail = repmat({''}, numel(kcatList.rxns), 1); + has = ~isnan(kcatList.similarity); + kcatList.detail(has) = cellstr("similarity=" + string(kcatList.similarity(has))); + end + saveKcatSource(model, kcatList, name, 'modelAdapter', modelAdapter, ... + 'generator', 'kcatsFromOKP', 'parameters', parameters, 'data', ['OKP job ' job.jobId]); + fprintf('OKP (%s) kcats for %d reactions written to %s\n', method, ... + numel(unique(kcatList.rxns(kcatList.kcats > 0))), file); +end +end + +function adoptSharedResult(model, modelAdapter, dataDir, method, jobFile, outFile) +% A result that fetchOpenKineticsPredictor stored by itself, in +% data/OKP_output.csv with data/OKP_job.txt, is taken over for this method +% only when its job is for this method and its predictions are labelled +% with this method. +shared = fullfile(dataDir, 'OKP_output.csv'); +sharedJob = readJobFile(fullfile(dataDir, 'OKP_job.txt')); +ok = isfile(shared) && isfield(sharedJob, 'jobId') && isfield(sharedJob, 'method') && ... + strcmpi(sharedJob.method, method); +if ok + list = readOpenKineticsPredictorOutput(model, 'outFile', shared, 'modelAdapter', modelAdapter); + predicted = list.kcatSource(startsWith(list.kcatSource, 'OKP-') & ... + ~ismember(lower(list.kcatSource), {'okp-brenda','okp-sabio-rk','okp-uniprot'})); + ok = ~isempty(predicted) && all(strcmpi(predicted, ['OKP-' method])); +end +if ~ok + error('kcatsFromOKP:noStored', ['No stored OKP result for %s (%s). Call kcatsFromOKP ' ... + 'without ''useStored'' to submit or fetch a job.'], method, outFile) +end +copyfile(shared, outFile); +sharedJob.method = method; +sharedJob.resultOf = sharedJob.jobId; +writeJobFile(jobFile, sharedJob); +end + +function job = readJobFile(file) +% Fields of an OKP job file ('key: value' per line), as a struct. +job = struct(); +if ~isfile(file) + return +end +lines = strsplit(fileread(file), newline); +for i = 1:numel(lines) + tok = regexp(lines{i}, '^([A-Za-z]\w*):\s*(.*?)\s*$', 'tokens', 'once'); + if ~isempty(tok) + job.(tok{1}) = tok{2}; + end +end +end + +function writeJobFile(file, job) +fid = fopen(file, 'w'); +for f = {'jobId','method','submittedAt','ecRxns','resultOf'} + if isfield(job, f{1}) + fprintf(fid, '%s: %s\n', f{1}, job.(f{1})); + end +end +fclose(fid); +end + +function n = countRxns(ecRxns) +if islogical(ecRxns) + n = sum(ecRxns); +else + n = numel(unique(ecRxns)); +end +end + +function warnSubset(ecRxns, nRxns, file) +% A subset written under the default name replaces the full file. +if ~isempty(ecRxns) && countRxns(ecRxns) < nRxns && isfile(file) + printOrange(sprintf(['%s is replaced by kcats for %d reactions only. Give saveAs ' ... + 'to keep it.\n'], file, countRxns(ecRxns))); +end +end + +function checkOptions(args, names, functionName) +% Options are name-value pairs with known names, so a misspelled option is +% an error instead of being taken as a positional argument. +id = [functionName ':arguments']; +given = args(1:2:end); +if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given)) + error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', ')) +end +unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names); +if ~isempty(unknown) + error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ... + strjoin(names, ', ')) +end +end diff --git a/src/gather_kcats/loadBrendaMeasurements.m b/src/gather_kcats/loadBrendaMeasurements.m new file mode 100644 index 00000000..3023f4c7 --- /dev/null +++ b/src/gather_kcats/loadBrendaMeasurements.m @@ -0,0 +1,111 @@ +function measurements = loadBrendaMeasurements(varargin) +% loadBrendaMeasurements Load the BRENDA measurement table. +% +% Reads measurements.tsv.xz, or measurements.tsv when there is no .xz file, +% from the BRENDA database folder of the model adapter (next to kcat.tsv, +% sa.tsv and mw.tsv). A .xz file is decompressed with the xz command, which +% has to be on the system path. The table has one row per wild-type +% BRENDA kcat with an EC number, after the outlier screen, with the +% substrate, organism, UniProt accession and sequence id of each +% measurement. geckopy reads the same file (load_brenda_measurements). +% +% Name-Value Arguments +% -------------------- +% modelAdapter : ModelAdapter +% a loaded model adapter (default: the current default model adapter). +% folder : char +% folder with measurements.tsv.xz or measurements.tsv, instead of the +% adapter's BRENDA folder. +% +% Returns +% ------- +% measurements : struct +% one field per column of the file (ec, substrate, substrate_inchikey, +% organism, taxid, uniprot, seq_id, temperature, ph and pmid as cell +% arrays of char; kcat as double), plus log10kcat and release (the +% release line of the file, e.g. 'BRENDA release 2026.1'). +% +% Examples +% -------- +% measurements = loadBrendaMeasurements(); +% +% See also +% -------- +% kcatsFromECTree, ecTreeEstimate, loadBRENDAdata + +checkOptions(varargin, {'modelAdapter','folder'}, 'loadBrendaMeasurements'); +p = parseGECKOargs(varargin, {'modelAdapter', []; 'folder', []}); +folder = p.folder; +if isempty(folder) + modelAdapter = p.modelAdapter; + if isempty(modelAdapter) + modelAdapter = ModelAdapterManager.getDefault(); + if isempty(modelAdapter) + error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.') + end + end + folder = modelAdapter.getBrendaDBFolder(); +end +xzFile = fullfile(folder, 'measurements.tsv.xz'); +file = fullfile(folder, 'measurements.tsv'); +tempFile = ''; +if isfile(xzFile) + tempFile = [tempname() '.tsv']; + cleanup = onCleanup(@() deleteIfExists(tempFile)); %#ok + [status, output] = system(sprintf('xz -dc "%s" > "%s"', xzFile, tempFile)); + if status ~= 0 + error('loadBrendaMeasurements:xz', ['Could not decompress %s with the xz command ' ... + '(install xz or decompress the file to measurements.tsv): %s'], xzFile, strtrim(output)) + end + file = tempFile; +elseif ~isfile(file) + error('loadBrendaMeasurements:missing', ['No BRENDA measurement table (measurements.tsv) in %s. ' ... + 'It comes with the BRENDA files of GECKO (databases folder).'], folder) +end +fid = fopen(file, 'r', 'n', 'UTF-8'); +first = fgetl(fid); +header = strsplit(fgetl(fid), '\t'); +data = textscan(fid, repmat('%s', 1, numel(header)), 'Delimiter', '\t', 'Whitespace', '', ... + 'ReturnOnError', false); +fclose(fid); +if ~all(ismember({'ec', 'kcat'}, header)) + error('loadBrendaMeasurements:columns', '%s lacks the columns ec and kcat.', file) +end +measurements = struct(); +for c = 1:numel(header) + measurements.(matlab.lang.makeValidName(header{c})) = data{c}; +end +measurements.kcat = str2double(measurements.kcat); +keep = measurements.kcat > 0 & ~cellfun(@isempty, measurements.ec); +for f = fieldnames(measurements)' + measurements.(f{1}) = measurements.(f{1})(keep); +end +measurements.ec = strtrim(measurements.ec); +measurements.log10kcat = log10(measurements.kcat); +tok = regexp(first, '^#\s*(BRENDA release [^ ]+)', 'tokens', 'once'); +measurements.release = ''; +if ~isempty(tok) + measurements.release = tok{1}; +end +end + +function deleteIfExists(file) +if isfile(file) + delete(file) +end +end + +function checkOptions(args, names, functionName) +% Options are name-value pairs with known names, so a misspelled option is +% an error instead of being taken as a positional argument. +id = [functionName ':arguments']; +given = args(1:2:end); +if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given)) + error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', ')) +end +unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names); +if ~isempty(unknown) + error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ... + strjoin(names, ', ')) +end +end diff --git a/src/gather_kcats/loadKcatSource.m b/src/gather_kcats/loadKcatSource.m new file mode 100644 index 00000000..105462f3 --- /dev/null +++ b/src/gather_kcats/loadKcatSource.m @@ -0,0 +1,385 @@ +function [kcatList, report] = loadKcatSource(model, name, varargin) +% loadKcatSource Read a kcat source file and map its rows to an ecModel. +% +% Reads data/kcats/.tsv (see saveKcatSource) and maps every row to +% the model.ec reactions it applies to, by conventional reaction and +% enzyme set (see getEcRxnKeys): +% +% 1. A row with rxn and enzymes applies to the model.ec rows with that +% conventional reaction and that enzyme set. +% 2. A row with only enzymes applies to every model.ec row with that +% enzyme set; a row with only rxn to every model.ec row of that +% conventional reaction (curated rows; saveKcatSource always writes +% both). +% 3. A row whose kcat is missing, not a number, infinite, or not above 0 +% is reported as invalid and not applied. +% 4. A row that matches nothing is reported, never dropped silently. If a +% model.ec row has at least half of the row's enzymes, that partial +% match is reported as well, but not applied. +% +% The enzymes of a row may be listed in any order. +% +% The file is read as UTF-8 (a leading byte-order mark is ignored). The +% '#' lines before the column header are the header; '#' lines and blank +% lines further down are skipped, as are rows without a filled field (a row +% of empty quoted fields included). Fields wrapped in double quotes, as a +% spreadsheet may save them, are unwrapped; a field that opens a double quote +% and does not close it is an error. kcat and log10_sd must be plain +% numbers (12, 0.5, 1e-05); other text, such as '5,5' with a decimal comma, +% is reported as invalid. A row with more filled fields than there are +% columns is an error. +% +% Parameters +% ---------- +% model : struct +% an ecModel in GECKO 3 format (with ecModel.ec structure). +% name : char +% name of the source (data/kcats/.tsv in the project folder), or +% the path to a kcat source file. +% +% Name-Value Arguments +% -------------------- +% modelAdapter : ModelAdapter +% a loaded model adapter (default: the current default model adapter). +% +% Returns +% ------- +% kcatList : struct +% kcat values per model.ec reaction, as used by mergeKcats and +% assignKcatValues: source (the source name), rxns, kcats, +% substrates, eccodes, wildcardLvl and origin (from the detail +% column), kcatSource (the per-row source), log10sd, detail (the detail +% column), and line (the line of the file each entry comes from). +% report : struct +% - invalid: table of the file rows with a missing or invalid kcat; +% - unmatched: table of the file rows that apply to no model.ec row; +% - partial: table of rows that only partly match an enzyme set, with +% the model.ec reaction and its enzymes; +% - header: the '#' header lines of the file, as field: value (for +% instance header.source, header.parameters); +% - records: the rows of the file as read, one field per column (kcat +% and log10_sd as double, other columns as cell of char) and line, +% the line number of each row. +% +% Examples +% -------- +% kcatList = loadKcatSource(ecModel, 'brenda'); +% [kcatList, report] = loadKcatSource(ecModel, 'custom'); +% +% See also +% -------- +% saveKcatSource, kcatsFromBrenda, getEcRxnKeys + +checkOptions(varargin, {'modelAdapter'}, 'loadKcatSource'); +p = parseGECKOargs(varargin, {'modelAdapter', []}); + +if isfile(name) + filename = name; +else + modelAdapter = p.modelAdapter; + if isempty(modelAdapter) + modelAdapter = ModelAdapterManager.getDefault(); + if isempty(modelAdapter) + error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.') + end + end + filename = fullfile(modelAdapter.params.path, 'data', 'kcats', [name '.tsv']); + if ~isfile(filename) + error('loadKcatSource:missing', ['No kcat source file %s. Make it with the ' ... + 'kcatsFrom function of this source (kcatsFromBrenda, kcatsFromDLKcat, ' ... + 'kcatsFromOKP), or with saveKcatSource.'], filename) + end +end +[records, meta] = readSourceFile(filename); +sourceName = ''; +if isfield(meta, 'source') + sourceName = meta.source; +end + +[baseRxns, enzymeSets] = getEcRxnKeys(model); +nEc = numel(baseRxns); +nRec = numel(records.kcat); + +% Lookup tables: key -> model.ec rows. +byPair = groupIndex(strcat(baseRxns, '|', enzymeSets)); +byBase = groupIndex(baseRxns); +byEnz = groupIndex(enzymeSets); +% accession -> model.ec rows containing it, for partial matches. +accRows = cell(nEc, 1); +for i = 1:nEc + if ~isempty(enzymeSets{i}) + accRows{i} = strsplit(enzymeSets{i}, ' + '); + end +end +accIdx = repelem((1:nEc)', cellfun(@numel, accRows)); +byAcc = groupIndex([accRows{:}]', accIdx); + +invalid = ~(records.kcat > 0) | ~isfinite(records.kcat); +matchRec = cell(nRec, 1); +matchEc = cell(nRec, 1); +unmatched = false(nRec, 1); +partialRec = zeros(0, 1); partialEc = zeros(0, 1); +for r = find(~invalid)' + rxn = records.rxn{r}; + enz = normalizeEnzymes(records.enzymes{r}); + if ~isempty(rxn) && ~isempty(enz) + hit = lookup(byPair, [rxn '|' enz]); + elseif ~isempty(enz) + hit = lookup(byEnz, enz); + elseif ~isempty(rxn) + hit = lookup(byBase, rxn); + else + hit = []; + end + if isempty(hit) + unmatched(r) = true; + if ~isempty(enz) + wanted = strsplit(enz, ' + '); + candidates = unique(cell2mat(cellfun(@(a) lookup(byAcc, a), wanted(:), 'UniformOutput', false))); + if ~isempty(rxn) + candidates = intersect(candidates, lookup(byBase, rxn)); + end + for c = candidates(:)' + if mean(ismember(wanted, accRows{c})) >= 0.5 + partialRec(end+1, 1) = r; %#ok + partialEc(end+1, 1) = c; %#ok + end + end + end + else + matchRec{r} = repmat(r, numel(hit), 1); + matchEc{r} = hit(:); + end +end +rec = vertcat(matchRec{:}, zeros(0, 1)); +ec = vertcat(matchEc{:}, zeros(0, 1)); + +kcatList.source = sourceName; +kcatList.rxns = reshape(model.ec.rxns(ec), [], 1); +kcatList.kcats = records.kcat(rec); +kcatList.substrates = records.substrate(rec); +kcatList.eccodes = records.ec_code(rec); +kcatList.kcatSource = records.source(rec); +kcatList.log10sd = records.log10_sd(rec); +kcatList.detail = records.detail(rec); +[kcatList.wildcardLvl, kcatList.origin] = parseDetail(records.detail(rec)); +kcatList.line = records.line(rec); + +report.invalid = table(records.line(invalid), records.rxn(invalid), records.enzymes(invalid), ... + records.kcat(invalid), 'VariableNames', {'line','rxn','enzymes','kcat'}); +report.unmatched = table(records.line(unmatched), records.rxn(unmatched), records.enzymes(unmatched), ... + records.kcat(unmatched), 'VariableNames', {'line','rxn','enzymes','kcat'}); +report.partial = table(records.line(partialRec), records.rxn(partialRec), records.enzymes(partialRec), ... + reshape(model.ec.rxns(partialEc), [], 1), enzymeSets(partialEc), ... + 'VariableNames', {'line','rxn','enzymes','ecRxn','ecEnzymes'}); +if any(invalid) + printOrange(sprintf('%d of %d rows of %s have no valid kcat; see report.invalid.\n', ... + sum(invalid), nRec, filename)); +end +if any(unmatched) + printOrange(sprintf('%d of %d rows of %s apply to no reaction of this model; see report.unmatched.\n', ... + sum(unmatched), nRec, filename)); +end +report.header = meta; +report.records = records; +end + +function map = groupIndex(keys, rows) +% containers.Map from each key to the rows (default 1:n) that have it. +if nargin < 2 + rows = (1:numel(keys))'; +end +map = containers.Map('KeyType', 'char', 'ValueType', 'any'); +if isempty(keys) + return +end +[u, ~, g] = unique(keys(:)); +groups = accumarray(g, rows(:), [], @(x) {sort(x)}); +for i = 1:numel(u) + if ~isempty(u{i}) + map(u{i}) = groups{i}; + end +end +end + +function rows = lookup(map, key) +if isKey(map, key) + rows = map(key); +else + rows = zeros(0, 1); +end +end + +function enz = normalizeEnzymes(enz) +% Sorted and joined as getEcRxnKeys does, so hand-written rows match too. +if isempty(enz) + return +end +parts = strtrim(strsplit(enz, '+')); +parts = unique(parts(~cellfun(@isempty, parts))); +enz = strjoin(sort(parts(:)'), ' + '); +end + +function [wc, origin] = parseDetail(detail) +wc = nan(numel(detail), 1); +origin = nan(numel(detail), 1); +for i = 1:numel(detail) + t = regexp(detail{i}, 'wc=(\d+)', 'tokens', 'once'); + if ~isempty(t) + wc(i) = str2double(t{1}); + end + t = regexp(detail{i}, 'origin=(\d+)', 'tokens', 'once'); + if ~isempty(t) + origin(i) = str2double(t{1}); + end +end +end + +function [records, meta] = readSourceFile(filename) +% The rows and '#' header lines of a kcat source file, as they are. +text = readUtf8(filename); +lines = regexp(text, '\r?\n', 'split'); + +meta = struct(); +k = 1; +while k <= numel(lines) && (isempty(strtrim(lines{k})) || startsWith(unquoteField(lines{k}), '#')) + [key, value] = parseHeaderLine(lines{k}); + if ~isempty(key) + meta.(key) = value; + end + k = k + 1; +end +if k > numel(lines) + error('loadKcatSource:noHeader', '%s has no column header.', filename) +end +columns = cellfun(@unquoteField, strsplit(lines{k}, sprintf('\t'), ... + 'CollapseDelimiters', false), 'UniformOutput', false); +if ~all(ismember({'kcat','source'}, columns)) || ~any(ismember({'rxn','enzymes'}, columns)) + error('loadKcatSource:columns', ['%s needs the columns kcat and source, and rxn ' ... + 'and/or enzymes.'], filename) +end +named = columns(~cellfun(@isempty, columns)); +if numel(unique(named)) < numel(named) || any(strcmp(columns, 'line')) + error('loadKcatSource:columns', '%s has a column name twice, or a column named line.', filename) +end +nCol = numel(columns); + +trimmed = strtrim(lines); +skip = cellfun(@isempty, trimmed) | startsWith(trimmed, '#'); +commentLike = find(startsWith(trimmed, '"#')); +for q = commentLike(:)' + skip(q) = startsWith(unquoteField(trimmed{q}), '#'); +end +skip(1:k) = true; +kept = find(~skip); +L = string(lines(kept)); +L = L(:); +F = strings(numel(kept), nCol); +nTabs = count(L, sprintf('\t')); +regular = nTabs == nCol - 1; +if any(regular) + % Rows with exactly one field per column, split in one go. + F(regular, :) = reshape(split(L(regular), sprintf('\t'), 2), [], nCol); +end +for r = find(~regular)' + fields = strsplit(char(L(r)), sprintf('\t'), 'CollapseDelimiters', false); + if numel(fields) > nCol + if any(~cellfun(@isempty, strtrim(fields(nCol+1:end)))) + error('loadKcatSource:fields', '%s, line %d has more fields than the %d columns.', ... + filename, kept(r), nCol) + end + fields = fields(1:nCol); + end + fields(end+1:nCol) = {''}; + F(r, :) = string(fields); +end +F = strtrim(F); +quoted = find(startsWith(F, '"')); +unclosed = quoted(~(strlength(F(quoted)) >= 2 & endsWith(F(quoted), '"'))); +if ~isempty(unclosed) + badRow = min(mod(unclosed - 1, size(F, 1)) + 1); + error('loadKcatSource:quote', '%s, line %d has a field with an opening double quote and no closing one.', ... + filename, kept(badRow)) +end +for q = quoted(:)' + F(q) = unquoteField(char(F(q))); +end +filled = any(F ~= "", 2); % a row of tabs only is skipped +values = cellstr(F(filled, :)); +if isempty(values) + values = cell(0, nCol); +end +lineNo = kept(filled); +lineNo = lineNo(:); +n = numel(lineNo); + +records = struct(); +for c = 1:nCol + if isempty(columns{c}) + continue + end + name = matlab.lang.makeValidName(columns{c}); + v = values(:, c); + if any(strcmp(columns{c}, {'kcat','log10_sd'})) + v = parseKcatNumber(v); + end + records.(name) = v; +end +for c = {'rxn','enzymes','substrate','source','detail','ec_code','note'} + if ~isfield(records, c{1}) + records.(c{1}) = repmat({''}, n, 1); + end +end +if ~isfield(records, 'log10_sd') + records.log10_sd = nan(n, 1); +end +records.line = lineNo; +end + +function text = readUtf8(filename) +fid = fopen(filename, 'r', 'n', 'UTF-8'); +if fid < 0 + error('loadKcatSource:read', 'Cannot read %s', filename) +end +cleanup = onCleanup(@() fclose(fid)); +text = fread(fid, [1 Inf], '*char'); +text = regexprep(text, ['^' char(65279)], ''); +end + +function x = parseKcatNumber(texts) +% Plain numbers only: '5,5' or '12 /s' read as NaN. +x = nan(numel(texts), 1); +ok = ~cellfun(@isempty, regexp(texts(:), '^[-+]?(\d+\.?\d*|\.\d+)([eE][-+]?\d+)?$|^[-+]?Inf$', 'once')); +x(ok) = str2double(texts(ok)); +end + +function [key, value] = parseHeaderLine(line) +key = ''; value = ''; +tok = regexp(unquoteField(line), '^\s*#\s*([A-Za-z][A-Za-z0-9_]{0,62})\s*:\s?(.*)$', 'tokens', 'once'); +if ~isempty(tok) + key = lower(tok{1}); + value = strtrim(tok{2}); +end +end + +function t = unquoteField(t) +t = strtrim(t); +if numel(t) >= 2 && t(1) == '"' && t(end) == '"' + t = strtrim(strrep(t(2:end-1), '""', '"')); +end +end + +function checkOptions(args, names, functionName) +% Options are name-value pairs with known names, so a misspelled option is +% an error instead of being taken as a positional argument. +id = [functionName ':arguments']; +given = args(1:2:end); +if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given)) + error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', ')) +end +unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names); +if ~isempty(unknown) + error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ... + strjoin(names, ', ')) +end +end diff --git a/src/gather_kcats/mergeDLKcatAndFuzzyKcats.m b/src/gather_kcats/mergeDLKcatAndFuzzyKcats.m index 4bb1e0dd..364efeac 100644 --- a/src/gather_kcats/mergeDLKcatAndFuzzyKcats.m +++ b/src/gather_kcats/mergeDLKcatAndFuzzyKcats.m @@ -28,7 +28,8 @@ % -------------------- % topOriginLimit : double % origin limit for prioritized BRENDA matches. Origin is explained in -% more detail below (default 6). +% more detail below (default 4: BRENDA matches of origin 5 and 6, from +% specific activities, rank after DLKcat; use 6 to rank them above). % bottomOriginLimit : double % origin limit for low priority BRENDA matches. Origin is explained in % more detail below (default 6). @@ -74,7 +75,7 @@ % mergeKcats, readDLKcatOutput, fuzzyKcatMatching, assignKcatValues p = parseGECKOargs(varargin, { ... - 'topOriginLimit', 6; ... + 'topOriginLimit', 4; ... 'bottomOriginLimit', 6; ... 'wildcardLimit', 3}); topOriginLimit = p.topOriginLimit; diff --git a/src/gather_kcats/mergeKcats.m b/src/gather_kcats/mergeKcats.m index ad0f65c5..4930b305 100644 --- a/src/gather_kcats/mergeKcats.m +++ b/src/gather_kcats/mergeKcats.m @@ -27,13 +27,19 @@ % wildcardLimit / bottomOriginLimit. % % Any other token is matched against each row's source after folding -% to lowercase snake_case (e.g. 'dlkcat', 'catapro'). Sources not -% listed are dropped. +% to lowercase snake_case (e.g. 'dlkcat', 'catapro'). A leading 'okp_' +% of the row's folded source (the OKP- tag of OpenKineticsPredictor +% rows) is dropped for matching, so 'OKP-BRENDA' routes to the database +% tiers and 'OKP-CataPro' matches 'catapro'; the rows keep their +% source label. Sources not listed are dropped. % % Name-Value Arguments % -------------------- % topOriginLimit : double -% origin limit for database_top (default 6). +% origin limit for database_top (default 4). Origins 5 and 6 are specific +% activity times molecular weight kcats, which do not always beat a +% prediction; they rank after the other sources and are used where +% nothing else exists, or above DLKcat with topOriginLimit 6. % bottomOriginLimit : double % origin limit for database_bottom (default 6). % wildcardLimit : double @@ -87,7 +93,7 @@ % mergeDLKcatAndFuzzyKcats, readDLKcatOutput, fuzzyKcatMatching, assignKcatValues p = parseGECKOargs(varargin, { ... - 'topOriginLimit', 6; ... + 'topOriginLimit', 4; ... 'bottomOriginLimit', 6; ... 'wildcardLimit', 3; ... 'databaseSources', {'brenda','sabio_rk'}}); @@ -167,6 +173,7 @@ end token = cellfun(@normalizeSource, rawSource, 'UniformOutput', false); +token = regexprep(token, '^okp_', ''); isDb = ismember(token, dbSources); hasMeta = ~isnan(wcl) & ~isnan(origin); diff --git a/src/gather_kcats/readDLKcatOutput.m b/src/gather_kcats/readDLKcatOutput.m index f1cadc9f..d9aff5d3 100644 --- a/src/gather_kcats/readDLKcatOutput.m +++ b/src/gather_kcats/readDLKcatOutput.m @@ -16,6 +16,15 @@ % the obj.params.path folder specified in the modelAdapter). % modelAdapter : ModelAdapter % a loaded model adapter (default: the current default model adapter). +% strict : logical +% raise an error for a substrate that is not in model.metNames +% (readDLKcatOutput:unknownSubstrate). By default the rows with such a +% substrate are left out with a warning (default false). +% +% Rows without a numeric kcat ('NA', 'None', empty, text, 'inf') are left out +% before the reactions are checked. A file without any such row raises +% readDLKcatOutput:noKcats. A reaction that is not in model.ec.rxns raises +% readDLKcatOutput:unknownReaction. % % Returns % ------- @@ -45,9 +54,11 @@ p = parseGECKOargs(varargin, { ... 'outFile', []; ... - 'modelAdapter', []}); + 'modelAdapter', []; ... + 'strict', false}); outFile = p.outFile; modelAdapter = p.modelAdapter; +strict = p.strict; if isempty(modelAdapter) modelAdapter = ModelAdapterManager.getDefault(); @@ -65,36 +76,46 @@ DLKcatOutput = textscan(fID,'%s %s %s %s %s %s','Delimiter','\t','HeaderLines',1); fclose(fID); -% Check that DLKcat output file and model match (not fool proof, but good enough) [rxns, genes, subs, kcats] = deal(DLKcatOutput{[1,2,3,6]}); +% A row has a kcat when its kcat field is a plain finite number. +isNumber = ~cellfun(@isempty, regexp(strtrim(kcats), '^[-+]?(\d+\.?\d*|\.\d+)([eE][-+]?\d+)?$', 'once')); +kcatValues = nan(numel(kcats), 1); +kcatValues(isNumber) = str2double(kcats(isNumber)); +usable = isfinite(kcatValues); + % Check if it contains any kcat values -if all(cellfun(@isempty,kcats)) || all(strcmpi(kcats,'NA')) - error('DLKcat file does not contain any kcat values, please run runDLKcat() first.') +if ~any(usable) + error('readDLKcatOutput:noKcats', 'DLKcat file does not contain any kcat values, please run runDLKcat() first.') end -% Check that all substrates are in the model (case-insensitive: an SBML loader can +% Check that the substrates are in the model (case-insensitive: an SBML loader can % normalise metabolite-name capitalisation differently than whatever produced the -% DLKcat input, and that must not read as a genuinely missing substrate). +% DLKcat input, and that must not read as a genuinely missing substrate). Rows with +% another substrate are left out with a warning, or raise an error with 'strict'. matchMets = ismember(lower(subs),lower(model.metNames)); if ~all(matchMets) errorText = 'DLKcat was likely run with an input file that was generated from another ecModel, as the following substrates from DLKcat output cannot be found in model.metNames:'; - error('%s', ravenList(errorText,subs(~matchMets),false)) + if strict + error('readDLKcatOutput:unknownSubstrate', '%s', ravenList(errorText,subs(~matchMets),false)) + end + warning('readDLKcatOutput:unknownSubstrate', 'Rows with a substrate that is not in model.metNames are left out: %s', ... + strjoin(unique(subs(~matchMets))', ', ')) + usable = usable & matchMets; end -% Check that all reactions are in model.ec.rxns +% Check that the reactions of the rows with a kcat are in model.ec.rxns matchRxns = ismember(rxns,model.ec.rxns); -if ~all(matchRxns) - errorText = 'DLKcat was likely run with an input file that was generated from another ecModel, as the following reactions from DLKcat output cannot be found in model.metNames:'; - error('%s', ravenList(errorText,rxns(~matchRxns),false)) +if ~all(matchRxns(usable)) + errorText = 'DLKcat was likely run with an input file that was generated from another ecModel, as the following reactions from DLKcat output cannot be found in model.ec.rxns:'; + error('readDLKcatOutput:unknownReaction', '%s', ravenList(errorText,rxns(usable & ~matchRxns),false)) end -% Filter out entries with no numeric value -noOutput = cellfun(@isempty,regexpi(kcats,'[0-9]')); -kcats = str2double(kcats(~noOutput)); -rxns(noOutput) = []; -genes(noOutput) = []; -subs(noOutput) = []; +% Keep the entries with a numeric value +kcats = kcatValues(usable); +rxns = rxns(usable); +genes = genes(usable); +subs = subs(usable); % Make kcatList structure kcatList.source = 'DLKcat'; diff --git a/src/gather_kcats/readOpenKineticsPredictorOutput.m b/src/gather_kcats/readOpenKineticsPredictorOutput.m index 64cb3306..2574e20a 100644 --- a/src/gather_kcats/readOpenKineticsPredictorOutput.m +++ b/src/gather_kcats/readOpenKineticsPredictorOutput.m @@ -6,6 +6,10 @@ % constructs a kcatList structure, that can be used by assignKcatValues() to % populate the ecModel with kcat values. % +% CatRange predicts a class of kcat values, which OKP returns as its range +% (for instance '10 to 100 s^-1'). It is read as the geometric midpoint of +% the range, or half the upper bound for the class starting at 0. +% % The per-entry `Source kcat` column (e.g. 'Prediction from CatPred', % 'BRENDA', 'Sabio-RK', 'UniProt') is preserved in kcatList.kcatSource so % that assignKcatValues() records the actual provenance of each value. @@ -39,6 +43,8 @@ % - genes : gene identifiers, matching model.ec.genes. % - substrates : substrate names, matching model.metNames. % - kcats : kcat values in /sec. +% - similarity : the enzyme's highest sequence similarity to the method's +% training data, in percent (NaN without the similarity column) % - kcatSource : per-entry source as reported by OKP, prefixed with 'OKP-' % (e.g. 'OKP-CatPred', 'OKP-BRENDA', 'OKP-Sabio-RK', 'OKP-UniProt'). % @@ -92,8 +98,22 @@ error('OKP output file does not have the expected 5 columns (kcat, Source kcat, Extra Info kcat, Protein Sequence, Substrate): %s', outFile) end -% Drop header row +% Drop header row; the 'max similarity to training data' column, +% when present, gives the similarity. +header = cellfun(@(h) char(string(h)), raw(1,:), 'UniformOutput', false); +simCol = find(startsWith(header, 'max similarity to'), 1); raw = raw(2:end, :); +similarity = nan(size(raw, 1), 1); +if ~isempty(simCol) + for i = 1:size(raw, 1) + v = raw{i, simCol}; + if isnumeric(v) && ~isempty(v) + similarity(i) = v; + elseif ischar(v) || isstring(v) + similarity(i) = str2double(v); + end + end +end kcatsCol = raw(:,1); sourceKcatCol = raw(:,2); @@ -108,7 +128,7 @@ if isnumeric(v) kcats(i) = v; elseif ischar(v) || isstring(v) - kcats(i) = str2double(v); + kcats(i) = kcatFromText(char(v)); end end @@ -123,6 +143,7 @@ sequences = sequences(valid); smiles = smiles(valid); sourceKcatCol = sourceKcatCol(valid); +similarity = similarity(valid); if isempty(kcats) error('OKP file does not contain any numeric kcat values. Run the job at https://predictor.openkinetics.org/ first.') @@ -150,6 +171,7 @@ substratesOut = cell(0,1); kcatsOut = zeros(0,1); sourceOut = cell(0,1); +similarityOut = zeros(0,1); unmatched = 0; for i = 1:numel(sequences) @@ -208,6 +230,7 @@ substratesOut{end+1,1} = subName; kcatsOut(end+1,1) = kcats(i); sourceOut{end+1,1} = sourceKcatCol{i}; + similarityOut(end+1,1) = similarity(i); end end @@ -234,6 +257,7 @@ kcatList.substrates = substratesOut; kcatList.kcats = kcatsOut; kcatList.kcatSource = kcatSource; +kcatList.similarity = similarityOut; end function c = normalizeCellStrings(c) @@ -255,3 +279,25 @@ end end end + +function kcat = kcatFromText(v) +% A number, or a CatRange class range ' to s^-1' as its +% geometric midpoint (half the upper bound when the class starts at 0). +kcat = str2double(v); +if ~isnan(kcat) + return +end +bounds = regexp(strtrim(v), '^([0-9.eE+-]+)\s+to\s+([0-9.eE+-]+)(\s*s\^-1)?$', 'tokens', 'once'); +if isempty(bounds) + return +end +low = str2double(bounds{1}); +high = str2double(bounds{2}); +if isnan(low) || isnan(high) + return +elseif low > 0 + kcat = sqrt(low * high); +else + kcat = high / 2; +end +end diff --git a/src/gather_kcats/reviewKcatAssignment.m b/src/gather_kcats/reviewKcatAssignment.m index d53cf600..a5d265af 100644 --- a/src/gather_kcats/reviewKcatAssignment.m +++ b/src/gather_kcats/reviewKcatAssignment.m @@ -26,7 +26,8 @@ % ---------- % rxnIds, kcats, sources, ecCodes : cell/double % ec.rxns, ec.kcat, ec.source, ec.eccodes (or the equivalent -% subset), all the same length. +% subset), all the same length. The source labels 'custom' and +% 'standard' are recognised without regard to letter case. % % Name-Value Arguments % -------------------- diff --git a/src/gather_kcats/saveKcatSource.m b/src/gather_kcats/saveKcatSource.m new file mode 100644 index 00000000..a3861603 --- /dev/null +++ b/src/gather_kcats/saveKcatSource.m @@ -0,0 +1,385 @@ +function filename = saveKcatSource(model, kcatList, name, varargin) +% saveKcatSource Write a kcatList to a kcat source file of the project. +% +% Writes the kcat values of kcatList to data/kcats/.tsv in the +% project folder, the file that loadKcatSource reads back. Rows are keyed +% by their conventional reaction and enzyme set (see getEcRxnKeys), not +% by model.ec.rxns, so the file stays valid when the ecModel is rebuilt. +% kcatsFromBrenda, kcatsFromDLKcat and kcatsFromOKP write these files for +% their sources; use this function for a kcatList made in another way. +% +% The file is UTF-8 text. It starts with '#' header lines (source, +% generator, parameters, data, kind, created), then a tab-separated table +% with the columns rxn, enzymes, substrate, kcat, log10_sd, source, +% detail, ec_code and note, sorted by all columns from rxn onwards. +% Left out are: +% - rows whose kcat is not a positive finite number (0 means no value +% was found); +% - rows of model.ec reactions without enzymes, which have no enzyme +% constraint and could not be told apart from their isozymes. +% +% Parameters +% ---------- +% model : struct +% the ecModel the kcatList refers to. +% kcatList : struct +% kcat values as returned by kcatsFromBrenda, fuzzyKcatMatching, +% readDLKcatOutput, readOpenKineticsPredictorOutput or mergeKcats: +% fields rxns and kcats, optionally source, substrates, eccodes, +% wildcardLvl, origin, kcatSource, log10sd and detail (further +% key=value pairs for the detail column). +% name : char +% name of the source; the file is .tsv. +% +% Name-Value Arguments +% -------------------- +% modelAdapter : ModelAdapter +% a loaded model adapter (default: the current default model adapter). +% folder : char +% folder to write to (default: data/kcats in the project folder). +% generator : char +% what produced the values (default: 'saveKcatSource'). +% parameters : struct +% settings used to produce the values, written as compact JSON with +% sorted keys (default: none). +% data : char +% version of the data the values come from, e.g. a BRENDA release +% (default: empty). +% kind : char +% 'gathered' (default) or 'curated'. +% +% A file whose header says 'kind: curated' or 'source: custom', or named +% custom.tsv, is never written. +% +% Returns +% ------- +% filename : char +% the file written. +% +% Examples +% -------- +% kcatList = fuzzyKcatMatching(ecModel); +% saveKcatSource(ecModel, kcatList, 'mybrenda'); +% +% See also +% -------- +% kcatsFromBrenda, loadKcatSource, getEcRxnKeys + +names = {'modelAdapter','folder','generator','parameters','data','kind'}; +checkOptions(varargin, names, 'saveKcatSource'); +p = parseGECKOargs(varargin, { ... + 'modelAdapter', []; ... + 'folder', []; ... + 'generator', 'saveKcatSource'; ... + 'parameters', struct(); ... + 'data', ''; ... + 'kind', 'gathered'}); +kind = validatestring(p.kind, {'gathered','curated'}); +name = char(name); +filename = kcatSourceFile(name, p.folder, p.modelAdapter); + +[baseRxns, enzymeSets] = getEcRxnKeys(model); +[found, idx] = ismember(kcatList.rxns(:), model.ec.rxns); +if ~all(found) + error('saveKcatSource:unknownRxns', '%s', ravenList( ... + 'These kcatList reactions are not in model.ec.rxns:', kcatList.rxns(~found), false)); +end + +n = numel(kcatList.rxns); +kcats = double(kcatList.kcats(:)); +if numel(kcats) ~= n + error('saveKcatSource:fields', 'kcatList.kcats and kcatList.rxns differ in length.') +end +substrate = textColumn(kcatList, 'substrates', n); +ecCode = textColumn(kcatList, 'eccodes', n); +extra = textColumn(kcatList, 'detail', n); +if isfield(kcatList, 'kcatSource') + source = textColumn(kcatList, 'kcatSource', n); +elseif isfield(kcatList, 'source') + source = repmat({char(kcatList.source)}, n, 1); +else + source = repmat({name}, n, 1); +end +wc = numColumn(kcatList, 'wildcardLvl', n); +origin = numColumn(kcatList, 'origin', n); +sd = numColumn(kcatList, 'log10sd', n); + +keep = kcats > 0 & isfinite(kcats); +noEnzymes = keep & cellfun(@isempty, enzymeSets(idx)); +if any(noEnzymes) + fprintf('%d kcats of reactions without enzymes are not written to %s.\n', sum(noEnzymes), filename); +end +keep = find(keep & ~noEnzymes); + +clean = @(c) regexprep(string(c(:)), '[\t\r\n]', ' '); +rows = strings(numel(keep), 9); +if ~isempty(keep) + wcText = strings(numel(keep), 1); + hasWc = ~isnan(wc(keep)); + wcText(hasWc) = "wc=" + string(fix(wc(keep(hasWc)))); + originText = strings(numel(keep), 1); + hasOrigin = ~isnan(origin(keep)); + originText(hasOrigin) = "origin=" + string(fix(origin(keep(hasOrigin)))); + detail = join([wcText, originText, strtrim(clean(extra(keep)))], "; ", 2); + detail = regexprep(detail, '^(; )+|(; )+$', ''); + detail = regexprep(detail, '(; ){2,}', '; '); + rows(:, 1) = clean(baseRxns(idx(keep))); + rows(:, 2) = clean(enzymeSets(idx(keep))); + rows(:, 3) = clean(substrate(keep)); + rows(:, 4) = formatNumbers(kcats(keep)); + rows(:, 5) = formatNumbers(sd(keep)); + rows(:, 6) = clean(source(keep)); + rows(:, 7) = detail; + rows(:, 8) = clean(ecCode(keep)); + % Sorted by the columns in this order, as geckopy sorts tuples: one key + % per row, the fields joined by a character below any in the text. + [~, order] = sort(join(rows(:, [1 2 3 6 4 5 7 8 9]), char(1), 2)); + rows = rows(order, :); +end + +folder = fileparts(filename); +if ~isfolder(folder) + mkdir(folder); +end +fid = fopen(filename, 'w', 'n', 'UTF-8'); +if fid < 0 + error('saveKcatSource:write', 'Cannot write %s', filename) +end +cleanup = onCleanup(@() fclose(fid)); +fprintf(fid, '# source: %s\n', name); +fprintf(fid, '# generator: %s (GECKO %s)\n', cleanText(p.generator), geckoVersion()); +fprintf(fid, '# parameters: %s\n', kcatSourceJson(p.parameters)); +fprintf(fid, '# data: %s\n', cleanText(p.data)); +fprintf(fid, '# kind: %s\n', kind); +fprintf(fid, '# created: %s\n', char(datetime('now', 'TimeZone', 'UTC', 'Format', 'yyyy-MM-dd''T''HH:mm:ss''Z'''))); +fprintf(fid, 'rxn\tenzymes\tsubstrate\tkcat\tlog10_sd\tsource\tdetail\tec_code\tnote\n'); +if ~isempty(rows) + fprintf(fid, '%s\n', join(rows, sprintf('\t'), 2)); +end +end + +function col = textColumn(s, field, n) +% A kcatList field as an n x 1 cell of char; a cell of several entries +% (e.g. all substrates of a reaction) is joined by '; '. +col = repmat({''}, n, 1); +if ~isfield(s, field) || isempty(s.(field)) + return +end +v = s.(field); +if ischar(v) || isstring(v) + v = cellstr(v); +end +if numel(v) ~= n + error('saveKcatSource:fields', 'kcatList.%s and kcatList.rxns differ in length.', field) +end +for i = 1:n + e = v{i}; + if iscell(e) + e = strjoin(cellfun(@char, e(:)', 'UniformOutput', false), '; '); + elseif isstring(e) + e = char(e); + elseif ~ischar(e) + e = ''; + end + col{i} = e; +end +end + +function col = numColumn(s, field, n) +col = nan(n, 1); +if isfield(s, field) && ~isempty(s.(field)) + if numel(s.(field)) ~= n + error('saveKcatSource:fields', 'kcatList.%s and kcatList.rxns differ in length.', field) + end + col = double(s.(field)(:)); +end +end + +function t = formatNumbers(x) +% formatKcatNumber for a vector, in a few vectorized passes. +x = x(:); +t = strings(numel(x), 1); +whole = isfinite(x) & x == round(x) & abs(x) < 1e15; +t(whole) = compose('%d', x(whole)); +t(isinf(x) & x > 0) = "Inf"; +t(isinf(x) & x < 0) = "-Inf"; +open = find(isfinite(x) & ~whole); +for digits = 1:17 + if isempty(open) + break + end + candidate = compose(sprintf('%%.%dg', digits), x(open)); + hit = str2double(candidate) == x(open); + t(open(hit)) = candidate(hit); + open = open(~hit); +end +end + +function t = cleanText(t) +t = regexprep(char(t), '[\t\r\n]', ' '); +end + +function v = geckoVersion() +v = ''; +file = fullfile(findGECKOroot, 'version.txt'); +if isfile(file) + v = strtrim(fileread(file)); +end +end + +function filename = kcatSourceFile(name, folder, modelAdapter) +name = char(name); +if isempty(regexp(name, '^[A-Za-z0-9_.-]+$', 'once')) + error('saveKcatSource:invalidName', ... + 'The source name "%s" may only contain letters, digits, ''_'', ''-'' and ''.''.', name) +end +if isempty(folder) + if isempty(modelAdapter) + modelAdapter = ModelAdapterManager.getDefault(); + if isempty(modelAdapter) + error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.') + end + end + folder = fullfile(modelAdapter.params.path, 'data', 'kcats'); +end +filename = fullfile(char(folder), [name '.tsv']); +if strcmpi(name, 'custom') + error('saveKcatSource:curated', ['custom.tsv holds curated kcats and is not ' ... + 'written by GECKO; edit it by hand.']) +end +if isfile(filename) + meta = readHeaderLines(filename); + if (isfield(meta, 'kind') && strcmpi(meta.kind, 'curated')) || ... + (isfield(meta, 'source') && strcmpi(meta.source, 'custom')) + error('saveKcatSource:curated', '%s is curated by hand and is not overwritten.', filename) + end +end +end + +function meta = readHeaderLines(filename) +% Only the header lines at the top, so that a damaged table does not stop +% a gathered file from being written again. +meta = struct(); +fid = fopen(filename, 'r', 'n', 'UTF-8'); +if fid < 0 + return +end +cleanup = onCleanup(@() fclose(fid)); +line = fgetl(fid); +if ischar(line) + line = regexprep(line, ['^' char(65279)], ''); +end +while ischar(line) && (isempty(strtrim(line)) || startsWith(unquoteField(line), '#')) + [key, value] = parseHeaderLine(line); + if ~isempty(key) + meta.(key) = value; + end + line = fgetl(fid); +end +end + +function j = kcatSourceJson(v) +if isstruct(v) && isscalar(v) + f = sort(fieldnames(v)); + parts = cell(1, numel(f)); + for k = 1:numel(f) + parts{k} = [jsonString(f{k}) ':' kcatSourceJson(v.(f{k}))]; + end + j = ['{' strjoin(parts, ',') '}']; +elseif ischar(v) || (isstring(v) && isscalar(v)) + j = jsonString(char(v)); +elseif iscell(v) + j = ['[' strjoin(cellfun(@kcatSourceJson, v(:)', 'UniformOutput', false), ',') ']']; +elseif (isnumeric(v) || islogical(v)) && numel(v) ~= 1 + j = ['[' strjoin(arrayfun(@kcatSourceJson, v(:)', 'UniformOutput', false), ',') ']']; +elseif islogical(v) + j = 'false'; + if v + j = 'true'; + end +elseif isnumeric(v) + if ~isfinite(v) + j = 'null'; + else + j = formatKcatNumber(double(v)); + end +elseif isempty(v) + j = 'null'; +else + error('kcatSourceJson:type', 'Parameters of class %s cannot be written.', class(v)) +end +end + +function s = jsonString(s) +% JSON escapes, as Python's json.dumps(ensure_ascii=False). +out = ''; +for c = s + switch c + case '"', out = [out '\"']; %#ok + case '\', out = [out '\\']; %#ok + case char(8), out = [out '\b']; %#ok + case char(9), out = [out '\t']; %#ok + case char(10), out = [out '\n']; %#ok + case char(12), out = [out '\f']; %#ok + case char(13), out = [out '\r']; %#ok + otherwise + if double(c) < 32 + out = [out sprintf('\\u%04x', double(c))]; %#ok + else + out = [out c]; %#ok + end + end +end +s = ['"' out '"']; +end + +function t = formatKcatNumber(x) +if isnan(x) + t = ''; +elseif isinf(x) + t = 'Inf'; + if x < 0 + t = '-Inf'; + end +elseif x == round(x) && abs(x) < 1e15 + t = sprintf('%d', x); +else + for digits = 1:17 + t = sprintf('%.*g', digits, x); + if str2double(t) == x + break + end + end +end +end + +function [key, value] = parseHeaderLine(line) +key = ''; value = ''; +tok = regexp(unquoteField(line), '^\s*#\s*([A-Za-z][A-Za-z0-9_]{0,62})\s*:\s?(.*)$', 'tokens', 'once'); +if ~isempty(tok) + key = lower(tok{1}); + value = strtrim(tok{2}); +end +end + +function t = unquoteField(t) +t = strtrim(t); +if numel(t) >= 2 && t(1) == '"' && t(end) == '"' + t = strtrim(strrep(t(2:end-1), '""', '"')); +end +end + +function checkOptions(args, names, functionName) +% Options are name-value pairs with known names, so a misspelled option is +% an error instead of being taken as a positional argument. +id = [functionName ':arguments']; +given = args(1:2:end); +if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given)) + error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', ')) +end +unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names); +if ~isempty(unknown) + error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ... + strjoin(names, ', ')) +end +end diff --git a/src/gather_kcats/submitOpenKineticsPredictor.m b/src/gather_kcats/submitOpenKineticsPredictor.m index 27b18553..c35fbf59 100644 --- a/src/gather_kcats/submitOpenKineticsPredictor.m +++ b/src/gather_kcats/submitOpenKineticsPredictor.m @@ -7,8 +7,10 @@ % job id is also stored in data/OKP_job.txt, so fetchOpenKineticsPredictor can % pick it up later. % -% Predictors available via OKP: CataPro, CatPred, DLKcat, EITLEM, KinForm-H, -% KinForm-L, UniKP (see GET /api/v1/methods/). +% Predictors available via OKP: CataPro, CatPred, CatRange, DLKcat, EITLEM, +% KinForm-H, KinForm-L, OmniESI, OmniESI-O2DENet, TurNup, UniKP (see GET +% /api/v1/methods/). CatRange predicts a class of kcat values; +% readOpenKineticsPredictorOutput uses its geometric midpoint. % % Obtaining an API key: % The OKP API requires a personal Bearer key (looks like 'ak_...'). Keys diff --git a/src/gather_kcats/updateKcatSources.m b/src/gather_kcats/updateKcatSources.m new file mode 100644 index 00000000..368b0274 --- /dev/null +++ b/src/gather_kcats/updateKcatSources.m @@ -0,0 +1,272 @@ +function report = updateKcatSources(model, varargin) +% updateKcatSources Gather the kcat sources that the configuration needs. +% +% Lists the kcat source files that [kcat_assignment] in model_adapter.toml +% uses (see collectKcats), and gathers those that are missing or outdated +% with kcatsFromBrenda, kcatsFromECTree, kcatsFromDLKcat and kcatsFromOKP: +% +% - a file is outdated when its header records other settings than +% [kcat_sources.] asks for (presets set these for brenda and +% ec_tree), or, for brenda and ec_tree, another BRENDA release than the +% BRENDA files in use; +% - brenda and ec_tree are made again; dlkcat reads data/DLKcat.tsv if it exists and +% runs DLKcat (Docker) otherwise; okp_ submits or fetches a job, +% and reports it as pending while the job runs; +% - custom.tsv and other files it cannot gather are left as they are. +% +% Requirements are checked first: Docker for a DLKcat run and an +% OpenKineticsPredictor API key for OKP. Calling it again is safe: files +% that are current are not gathered again. +% +% Per-source settings are read from model_adapter.toml, for instance: +% +% [kcat_sources.brenda] +% aggregation = "median" +% +% [kcat_sources.okp_catapro] +% method = "CataPro" +% +% Parameters +% ---------- +% model : struct +% an ecModel in GECKO 3 format (with ecModel.ec structure). +% +% Name-Value Arguments +% -------------------- +% dryRun : logical +% only report what would be gathered (default false). +% modelAdapter : ModelAdapter +% a loaded model adapter (default: the current default model adapter). +% +% Returns +% ------- +% report : table +% one row per source: source, status (current, gathered, pending, +% outdated, missing, failed or skipped) and note. +% +% Examples +% -------- +% updateKcatSources(ecModel, 'dryRun', true) +% updateKcatSources(ecModel); +% +% See also +% -------- +% collectKcats, assignKcats, kcatsFromBrenda, kcatsFromDLKcat, kcatsFromOKP + +checkOptions(varargin, {'dryRun','modelAdapter'}, 'updateKcatSources'); +p = parseGECKOargs(varargin, {'dryRun', false; 'modelAdapter', []}); +modelAdapter = p.modelAdapter; +if isempty(modelAdapter) + modelAdapter = ModelAdapterManager.getDefault(); + if isempty(modelAdapter) + error('Either send in a modelAdapter or set the default model adapter in the ModelAdapterManager.') + end +end +params = modelAdapter.params; +config = kcatAssignmentConfig(params); +kcatDir = fullfile(params.path, 'data', 'kcats'); + +names = {}; +for s = 1:numel(config.stages) + for t = 1:numel(config.stages(s).files) + token = config.stages(s).files{t}; + if startsWith(token, 'database_') + token = 'brenda'; + end + if ~any(strcmp(names, token)) + names{end+1} = token; %#ok + end + end +end + +status = cell(numel(names), 1); +note = cell(numel(names), 1); +for k = 1:numel(names) + name = names{k}; + file = fullfile(kcatDir, [name '.tsv']); + wanted = struct(); + if isfield(config.sources, name) + wanted = config.sources.(name); + end + [status{k}, note{k}] = check(name, file, wanted); + if any(strcmp(status{k}, {'missing','outdated'})) && ~p.dryRun + [status{k}, note{k}] = gather(model, name, wanted, modelAdapter); + end +end +report = table(names(:), status, note, 'VariableNames', {'source','status','note'}); +disp(report) + + function [st, nt] = check(name, file, wanted) + st = 'current'; nt = ''; + if strcmp(name, 'custom') + st = 'skipped'; nt = 'curated by hand'; + return + elseif ~any(strcmp(name, {'brenda','ec_tree','homologs','dlkcat'})) && ~startsWith(name, 'okp_') + st = 'skipped'; nt = 'not a source GECKO gathers'; + return + end + if ~isfile(file) + st = 'missing'; + return + end + meta = readHeaderLines(file); + recorded = struct(); + if isfield(meta, 'parameters') && ~isempty(meta.parameters) + recorded = jsondecode(meta.parameters); + end + f = fieldnames(wanted); + for i = 1:numel(f) + if ~isfield(recorded, f{i}) || ~isequal(normalizeValue(recorded.(f{i})), normalizeValue(wanted.(f{i}))) + st = 'outdated'; + nt = sprintf('%s differs from model_adapter.toml', f{i}); + return + end + end + if any(strcmp(name, {'brenda','ec_tree','homologs'})) + release = brendaRelease(modelAdapter, name); + if isfield(meta, 'data') && ~isempty(release) && ~strcmp(meta.data, release) + st = 'outdated'; + nt = sprintf('made from %s; GECKO has %s', meta.data, release); + end + end + end +end + +function [st, nt] = gather(model, name, wanted, modelAdapter) +st = 'gathered'; nt = ''; +try + if strcmp(name, 'brenda') + args = {}; + if isfield(wanted, 'aggregation'), args = [args, {'aggregation', wanted.aggregation}]; end + if isfield(wanted, 'force_wildcard_level'), args = [args, {'forceWClvl', wanted.force_wildcard_level}]; end + kcatsFromBrenda(model, args{:}, 'modelAdapter', modelAdapter); + elseif strcmp(name, 'ec_tree') + args = {}; + if isfield(wanted, 'k'), args = {'k', double(wanted.k)}; end + kcatsFromECTree(model, args{:}, 'modelAdapter', modelAdapter); + elseif strcmp(name, 'homologs') + args = {}; + if isfield(wanted, 'k'), args = [args, {'k', double(wanted.k)}]; end + if isfield(wanted, 'min_identity'), args = [args, {'minIdentity', double(wanted.min_identity)}]; end + if isfield(wanted, 'coverage'), args = [args, {'coverage', double(wanted.coverage)}]; end + kcatsFromHomologs(model, args{:}, 'modelAdapter', modelAdapter); + elseif strcmp(name, 'dlkcat') + run = ~isfile(fullfile(modelAdapter.params.path, 'data', 'DLKcat.tsv')); + if run + [status, ~] = system('docker --version'); + if status ~= 0 + st = 'failed'; nt = 'DLKcat needs Docker to run'; + return + end + end + kcatsFromDLKcat(model, 'run', run, 'modelAdapter', modelAdapter); + else % okp_ + method = okpMethod(name, wanted); + resolveOkpApiKey('', modelAdapter.params.path); % errors without a key + [~, done] = kcatsFromOKP(model, 'method', method, 'saveAs', name, 'modelAdapter', modelAdapter); + if ~done + st = 'pending'; nt = sprintf('OKP job for %s still running; call again later', method); + end + end +catch err + st = 'failed'; nt = err.message; +end +end + +function method = okpMethod(name, wanted) +% The OKP method of okp_: from [kcat_sources.okp_] method, +% or the known method whose name gives this file name. +if isfield(wanted, 'method') + method = char(wanted.method); + return +end +known = {'CataPro','CatPred','CatRange','DLKcat','EITLEM','KinForm-H','KinForm-L', ... + 'OmniESI','OmniESI-O2DENet','TurNup','UniKP'}; +tags = cellfun(@(m) ['okp_' lower(regexprep(m, '[^A-Za-z0-9]+', '_'))], known, 'UniformOutput', false); +hit = strcmp(tags, name); +if ~any(hit) + error('updateKcatSources:okpMethod', ['Set the OKP method of %s in model_adapter.toml: ' ... + '[kcat_sources.%s] method = "..."'], name, name) +end +method = known{hit}; +end + +function v = normalizeValue(v) +if isstring(v) + v = char(v); +end +if ischar(v) + v = lower(v); +elseif islogical(v) + v = double(v); +end +end + +function release = brendaRelease(modelAdapter, name) +% The release line of the BRENDA file a source is made from. +release = ''; +files = struct('brenda', 'kcat.tsv', 'ec_tree', 'measurements.tsv', 'homologs', 'measurements.tsv'); +fid = fopen(fullfile(modelAdapter.getBrendaDBFolder(), files.(name)), 'r'); +if fid < 0 + return +end +line = fgetl(fid); +fclose(fid); +tok = regexp(line, '^#\s*(BRENDA release [^ ]+)', 'tokens', 'once'); +if ~isempty(tok) + release = tok{1}; +end +end + +function meta = readHeaderLines(filename) +% Only the header lines at the top, so that a damaged table does not stop +% a gathered file from being written again. +meta = struct(); +fid = fopen(filename, 'r', 'n', 'UTF-8'); +if fid < 0 + return +end +cleanup = onCleanup(@() fclose(fid)); +line = fgetl(fid); +if ischar(line) + line = regexprep(line, ['^' char(65279)], ''); +end +while ischar(line) && (isempty(strtrim(line)) || startsWith(unquoteField(line), '#')) + [key, value] = parseHeaderLine(line); + if ~isempty(key) + meta.(key) = value; + end + line = fgetl(fid); +end +end + +function [key, value] = parseHeaderLine(line) +key = ''; value = ''; +tok = regexp(unquoteField(line), '^\s*#\s*([A-Za-z][A-Za-z0-9_]{0,62})\s*:\s?(.*)$', 'tokens', 'once'); +if ~isempty(tok) + key = lower(tok{1}); + value = strtrim(tok{2}); +end +end + +function t = unquoteField(t) +t = strtrim(t); +if numel(t) >= 2 && t(1) == '"' && t(end) == '"' + t = strtrim(strrep(t(2:end-1), '""', '"')); +end +end + +function checkOptions(args, names, functionName) +% Options are name-value pairs with known names, so a misspelled option is +% an error instead of being taken as a positional argument. +id = [functionName ':arguments']; +given = args(1:2:end); +if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given)) + error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', ')) +end +unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names); +if ~isempty(unknown) + error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ... + strjoin(names, ', ')) +end +end diff --git a/src/gather_kcats/writeDLKcatInput.m b/src/gather_kcats/writeDLKcatInput.m index 3c8d46d9..1760a576 100644 --- a/src/gather_kcats/writeDLKcatInput.m +++ b/src/gather_kcats/writeDLKcatInput.m @@ -14,7 +14,9 @@ % ecRxns : logical % for which reactions (from model.ec.rxns) DLKcat should predict kcat % values, provided as logical vector with same length as model.ec.rxns -% (default: all reactions). +% (default: all reactions). A vector without true entries selects no +% reaction and gives an empty file. The rows follow the order of +% model.ec.rxns. % modelAdapter : ModelAdapter % a loaded model adapter (default: the current default model adapter). % onlyWithSmiles : logical @@ -40,9 +42,7 @@ % % See also % -------- -% runDLKcat, readDLKcatOutput - -[geckoPath, ~] = findGECKOroot(); +% runDLKcat, readDLKcatOutput, extractEnzymeSubstratePairs p = parseGECKOargs(varargin, { ... 'ecRxns', []; ... @@ -58,7 +58,7 @@ if isempty(ecRxnsSel) ecRxnsSel = true(numel(model.ec.rxns),1); -elseif ~logical(ecRxnsSel) +elseif ~islogical(ecRxnsSel) error('ecRxns should be provided as logical vector') elseif numel(ecRxnsSel)~=numel(model.ec.rxns) error('Length of ecRxns is not the same as model.ec.rxns') @@ -89,95 +89,26 @@ end end -if ~model.ec.geckoLight - origRxns = model.ec.rxns; -else - origRxns = extractAfter(model.ec.rxns,4); -end -origRxnsToInclude = origRxns(ecRxnsSel); - -% Map back to original reactions, to extract substrates -[sanityCheck,origRxnIdxs] = ismember(origRxnsToInclude,model.rxns); -if ~all(sanityCheck) - error('Not all reactions in model.ec.rxns are found in model.rxns') -end - -% Ignore selected metabolites (metal ions, proteins etc.). First check by -% name (case insensitive, without white spaces and special characters), -% then also try to match with metSmiles (if available). -metsNoSpecialChars = lower(regexprep(model.metNames,'[^0-9a-zA-Z]+','')); -if exist(fullfile(params.path,'data','DLKcatIgnoreMets.tsv'),'file') - fID = fopen(fullfile(params.path,'data','DLKcatIgnoreMets.tsv')); -else - fID = fopen(fullfile(geckoPath,'databases','DLKcatIgnoreMets.tsv')); -end -fileData = textscan(fID,'%s %s','delimiter','\t'); -fclose(fID); -[ignoreMets, ignoreSmiles] = deal(fileData{[1,2]}); -ignoreMets = lower(regexprep(ignoreMets,'[^0-9a-zA-Z]+','')); -ignoreSmiles(cellfun(@isempty,ignoreSmiles)) = []; - -ignoreMetsIdx = logical(ismember(metsNoSpecialChars,ignoreMets)); -if isfield(model,'metSmiles') - ignoreMetsIdx = ignoreMetsIdx | logical(ismember(model.metSmiles,ignoreSmiles)); -end -% Also leave out protein-usage pseudometabolites -ignoreMetsIdx = ignoreMetsIdx | startsWith(model.mets,'prot_'); -reducedS = model.S; -reducedS(ignoreMetsIdx,:) = 0; - -% Ignore currency metabolites if they occur in pairs. First check by -% name (case insensitive, without white spaces and special characters), -% then also try to match with metSmiles (if available). -if exist(fullfile(params.path,'data','DLKcatCurrencyMets.tsv'),'file') - fID = fopen(fullfile(params.path,'data','DLKcatCurrencyMets.tsv')); -else - fID = fopen(fullfile(geckoPath,'databases','DLKcatCurrencyMets.tsv')); -end -fileData = textscan(fID,'%s %s','delimiter','\t'); -fclose(fID); -[currencyMets(:,1), currencyMets(:,2)] = deal(fileData{[1,2]}); -currencyMets = lower(regexprep(currencyMets,'[^0-9a-zA-Z]+','')); - -for i=1:size(currencyMets,1) - subs = strcmp(currencyMets(i,1),metsNoSpecialChars); - prod = strcmp(currencyMets(i,2),metsNoSpecialChars); - [~,subsRxns]=find(reducedS(subs,:)); - [~,prodRxns]=find(reducedS(prod,:)); - pairRxns = intersect(subsRxns,prodRxns); - tempRedS=reducedS; - tempRedS([find(subs);find(prod)],pairRxns) = 0; - % Do not remove currency mets if no substrate remains - rxnsWithRemainingSubstrates = any(tempRedS(:,pairRxns) < 0,1); - reducedS([find(subs);find(prod)],intersect(pairRxns,pairRxns(rxnsWithRemainingSubstrates))) = 0; -end - -% origRxnIdxs already selects exactly the model.rxns columns for the requested -% ecRxns subset (one column per requested reaction, via origRxns(ecRxns) above), so -% clearedRedS needs no further filtering here. -clearedRedS = reducedS(:,origRxnIdxs); - -% Enumerate all substrates for each reaction. clearedRedS has one column per entry -% of ecRxnsSel, in that same order, so `reactions` here indexes *that subset*, not -% model.ec.rxns directly --- translate back to a real model.ec.rxns index before -% using it against model.ec.rxns / model.ec.rxnEnzMat, which are always full-length. -[substrates, reactions] = find(clearedRedS<0); -globalEcRxns = ecRxnsSel(reactions); - -% Enumerate all proteins for each reaction -[proteins, enzRows] = find(transpose(model.ec.rxnEnzMat(globalEcRxns,:))); +pairs = extractEnzymeSubstratePairs(model, 'ecRxns', ismember((1:numel(model.ec.rxns))', ecRxnsSel), ... + 'modelAdapter', modelAdapter); % Prepare output -out(1,:) = model.ec.rxns(globalEcRxns(enzRows)); -out(2,:) = model.ec.genes(proteins); -out(3,:) = model.metNames(substrates(enzRows)); +if isempty(pairs.ecRxn) + out = cell(6,0); + writeRows(filename, out) + writtenTable = out; + return +end +out(1,:) = model.ec.rxns(pairs.ecRxn); +out(2,:) = model.ec.genes(pairs.protein); +out(3,:) = model.metNames(pairs.met); if isfield(model,'metSmiles') - out(4,:) = model.metSmiles(substrates(enzRows)); + out(4,:) = model.metSmiles(pairs.met); else - out(4,:) = cell(numel(substrates(enzRows)),1); + out(4,:) = cell(numel(pairs.met),1); end -out(5,:) = model.ec.sequence(proteins); +out(5,:) = model.ec.sequence(pairs.protein); if onlyWithSmiles out(:,cellfun(@isempty,out(4,:))) = []; else @@ -186,11 +117,16 @@ out(6,:) = cell(numel(out(1,:)),1); out(6,:) = {'NA'}; -% Write file +writeRows(filename, out) +writtenTable = out; +end + +function writeRows(filename, out) +% Write the rows (one per column of out); an empty table gives an empty file. fID = fopen(filename,'w'); -fprintf(fID,'%s\t%s\t%s\t%s\t%s\t%s\n',out{:}); +if ~isempty(out) + fprintf(fID,'%s\t%s\t%s\t%s\t%s\t%s\n',out{:}); +end fclose(fID); fprintf('Model-specific DLKcat input stored at %s\n',filename); - -writtenTable = out; end diff --git a/src/get_enzyme_data/findECInDB.m b/src/get_enzyme_data/findECInDB.m index f23c8dbb..50abdd05 100644 --- a/src/get_enzyme_data/findECInDB.m +++ b/src/get_enzyme_data/findECInDB.m @@ -4,10 +4,14 @@ % For each gene, finds its matching database entries and takes the EC number % of the lightest-weight matching protein when a single EC number applies to % that gene; genes with several distinct EC numbers among their matches are -% also reported as conflicts (the first match is still used for EC). When -% gene_set has more than one gene (an enzyme complex), the numbers found for -% each gene are combined by intersection where they share a match (wildcards -% such as "-" are accounted for), otherwise by union. +% also reported as conflicts (the first match is still used for EC). Genes +% without an EC number are left out. When gene_set has more than one gene +% (an enzyme complex), the numbers found for each gene are combined by +% intersection where they share a match (a wildcard such as "1.1.1.-" matches +% the specific codes of its prefix), otherwise by union. The EC set of every +% gene set, one gene or a complex, is cleaned of a wildcard code such as +% "1.1.1.-" when a more specific code of the same prefix ("1.1.1.4") is +% present; only codes with four levels take part, and empty codes are removed. % % Parameters % ---------- @@ -88,25 +92,33 @@ end end -%EC: Find union and intersection between all units (only applies for -%complexes, i.e. length(EC_set) > 1): -uni_EC = strsplit(EC_set{1},' '); -int_EC = uni_EC; -for j = 2:length(EC_set) - other_EC = strsplit(EC_set{j},' '); - if isempty(uni_EC) - uni_EC = other_EC; - int_EC = other_EC; - elseif ~isempty(other_EC) - uni_EC = compare_wild([uni_EC other_EC]); - int_EC = intersection(int_EC,other_EC); - end +%EC: Split the codes of each gene, leave out the genes without any, and +%combine the rest (union and intersection only apply for complexes, i.e. more +%than one gene with codes): +tokens = cell(size(EC_set)); +for j = 1:length(EC_set) + codes = strsplit(EC_set{j},' '); + tokens{j} = codes(~cellfun(@isempty,codes)); end -%Use the intersection found, if any. If not, use the union: -if isempty(int_EC) - EC_set = uni_EC; +tokens = tokens(~cellfun(@isempty,tokens)); +if isempty(tokens) + EC_set = {}; +elseif isscalar(tokens) + EC_set = dropWildcardParents(tokens{1}); else - EC_set = int_EC; + uni_EC = tokens{1}; + int_EC = tokens{1}; + for j = 2:length(tokens) + uni_EC = dropWildcardParents([uni_EC tokens{j}]); + int_EC = wildcardIntersection(int_EC,tokens{j}); + end + %Use the intersection found, if any. If not, use the union: + if isempty(int_EC) + EC_set = uni_EC; + else + EC_set = int_EC; + end + EC_set = dropWildcardParents(EC_set); end %Add new codes as new possible isozymes and remove the initial "EC" text: @@ -118,7 +130,11 @@ end %EC_set = cellfun(@(x) extractAfter(x,2),EC_set,'UniformOutput',false);%remove 2 first chars -EC = strjoin(EC_set,';'); +if isempty(EC_set) + EC = ''; +else + EC = strjoin(EC_set,';'); +end %Delete repeated Uniprots (and the corresponding ECs): @@ -127,58 +143,70 @@ end %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% -function int_EC = intersection(prev_EC,new_EC) +function int_EC = wildcardIntersection(prev_EC,new_EC) %Finds the common elements between two cell arrays, if any. Also considers %wildcards (e.g. if 'EC1.1.1.1' is in one array and 'EC1.1.1.-' is in the -%other one, then 'EC1.1.1.1' is added to the intersection). +%other one, then 'EC1.1.1.1' is added to the intersection). A pair adds its +%code only when one code of the pair is the wildcard parent of the other, or +%the two are equal four-level codes. int_EC = {}; for i = 1:length(prev_EC) for j = 1:length(new_EC) - new_int = compare_wild({prev_EC{i} new_EC{j}}); - if length(new_int) == 1 - int_EC = [int_EC new_int]; + survivors = dropWildcardParents({prev_EC{i} new_EC{j}}); + if length(survivors) == 1 + int_EC = [int_EC survivors]; end end end -%When prev_EC carries both a code and its own wildcard parent (e.g. -%'EC1.1.1.1' and 'EC1.1.1.-'), both independently pair-match the same -%new_EC entry above and the loop appends the resolved code twice; dedupe. -int_EC = unique(int_EC,'stable'); end %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% -function int_EC = compare_wild(EC) -%Goes through a cell array of EC numbers, and erases any repetitions, -%considering also wildcards (e.g. will erase 'EC1.2.3.-' if 'EC1.2.3.4' is -%already present). - -%Trim all EC numbers of wild cards (e.g. 'EC1.2.-.-' -> 'EC1.2.'): -EC_trimmed = EC; -for i = 1:length(EC) - %Add a final dot for avoiding issues (e.g. 'EC1.1.1.1' & 'EC1.1.1.12'): - ECi = [EC{i} '.']; - pos = strfind(ECi,'-'); - if ~isempty(pos) - ECi = ECi(1:pos(1)-1); +function int_EC = dropWildcardParents(EC) +%Removes empty codes and every code that is a wildcard parent of another +%code in the cell array (e.g. 'EC1.2.3.-' when 'EC1.2.3.4' is present). Only +%codes with four levels are compared, so 'EC1.1.1' is neither a parent nor a +%child of 'EC1.1.1.4'. Equal codes collapse to the first. +EC = EC(~cellfun(@isempty,EC) & ~strcmp(EC,'EC')); +keep = true(1,numel(EC)); +for i = 1:numel(EC) + if ~keep(i) + continue; end - EC_trimmed{i} = ECi; -end - -%Compare all EC numbers between them to find if 1 fits in the other: -non_repeated = true(1,length(EC)); -for i = 1:length(EC)-1 - for j = i+1:length(EC) - ECi = EC_trimmed{i}; - ECj = EC_trimmed{j}; - %If ECj fits in ECi then ECj can be disregarded: - if strfind(ECi,ECj) - non_repeated(j) = false; - %Else, if ECi fits in ECj then ECi can be disregarded: - elseif strfind(ECj,ECi) - non_repeated(i) = false; + for j = i+1:numel(EC) + if ~keep(j) + continue; + end + iInJ = subsumes(EC{i},EC{j}); + jInI = subsumes(EC{j},EC{i}); + if iInJ && jInI + keep(j) = false; + elseif iInJ + keep(i) = false; + break; + elseif jInI + keep(j) = false; end end end - -int_EC = EC(non_repeated); - +int_EC = EC(keep); +end +%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% +function tf = subsumes(general,specific) +%True if the code general is equal to or a wildcard parent of the code +%specific; both carry the "EC" prefix and need four levels. +general = strsplit(extractAfter(general,2),'.'); +specific = strsplit(extractAfter(specific,2),'.'); +tf = false; +if numel(general) ~= 4 || numel(specific) ~= 4 + return; +end +for k = 1:4 + if strcmp(general{k},'-') + tf = true; + return; + end + if strcmp(specific{k},'-') || ~strcmp(general{k},specific{k}) + return; + end +end +tf = true; end diff --git a/src/get_enzyme_data/getECfromDatabase.m b/src/get_enzyme_data/getECfromDatabase.m index 3fd35fc7..ce498249 100644 --- a/src/get_enzyme_data/getECfromDatabase.m +++ b/src/get_enzyme_data/getECfromDatabase.m @@ -16,17 +16,20 @@ % of length model.ec.rxns that specifies which model.ec.eccodes entries % should be queried. Existing values in model.ec.eccodes will be wiped. % Entries that are indicated by false will be kept and not modified by -% this function (by default all model.ec.eccodes entries are populated -% by this function). +% this function, and are not searched for multiplicities. An empty +% logical array selects no entry, and the model is returned unchanged. +% When ecRxns is omitted or [], all model.ec.eccodes entries are +% populated by this function. % action : char % response action if multiple proteins with different EC numbers are % found for a given gene in a metabolic reaction (default 'display'): % -% - 'display' displays all found multiplicities. -% - 'ignore' ignore multiplicities and use the protein with the lowest -% index in the database. -% - 'add' adds all the multiple proteins as isozymes for the given -% reaction. +% - 'display' gives a warning that lists all found multiplicities and +% uses the protein with the lowest index in the database. +% - 'ignore' ignores multiplicities and uses the protein with the +% lowest index in the database. +% +% Any other action raises getECfromDatabase:unsupportedAction. % modelAdapter : ModelAdapter % a loaded model adapter (default: the current default model adapter). % @@ -53,6 +56,11 @@ action = p.action; modelAdapter = p.modelAdapter; +if ~(ischar(action) && any(strcmpi(action,{'display','ignore'}))) + error('getECfromDatabase:unsupportedAction', ... + 'action must be ''display'' or ''ignore''.') +end + if isempty(modelAdapter) modelAdapter = ModelAdapterManager.getDefault(); if isempty(modelAdapter) @@ -61,6 +69,10 @@ end params = modelAdapter.getParameters(); +if islogical(ecRxns) && isempty(ecRxns) + return +end + rxnEnzMat = model.ec.rxnEnzMat; genes = modelAdapter.getUniprotCompatibleGenes(model.ec.genes); @@ -96,9 +108,17 @@ conflicts = cell(1,4); rxnEnzMat = logical(rxnEnzMat); +if isempty(ecRxns) + selected = true(n,1); +else + selected = logical(ecRxns(:)); +end PB = progressReport(n, 'Assigning EC numbers from database'); for i = 1:n PB.count; + if ~selected(i) + continue + end gns = genes(rxnEnzMat(i,:).'); if ~isempty(gns) %Find match in Uniprot: @@ -176,10 +196,11 @@ function displayErrorMessage(conflicts,uniprot,kegg) STR = [STR, '\nIf a wrongly annotated case was found then call the ']; STR = [STR, 'getECfromDatabase.m function again with the option action']; STR = [STR, '= ignore\n\n']; +STR = [STR, 'The protein with the lowest index in the database was used for each of them.\n\n']; STR = [STR, 'If the conflicting proteins are desired to be kept as isozymes']; STR = [STR, ' then call the getECfromDatabase.m function']; STR = [STR, ' again with the option action = add\n']; -error(sprintf(STR)) +warning('getECfromDatabase:conflicts', '%s', sprintf(STR)) end function [geneIndex,geneHashMap]=hashGeneToProt(proteinDB) diff --git a/src/get_enzyme_data/getECfromGEM.m b/src/get_enzyme_data/getECfromGEM.m index dc89922a..c5996fcd 100644 --- a/src/get_enzyme_data/getECfromGEM.m +++ b/src/get_enzyme_data/getECfromGEM.m @@ -3,7 +3,8 @@ % % Uses the model.eccodes to populate the model.ec.eccodes field. EC numbers % must be formatted as four numbers separated by periods, possibly with -% trailing wildcards; incorrectly formatted EC numbers are skipped. +% trailing wildcards; incorrectly formatted EC numbers are skipped. A model without +% a model.eccodes field gives a warning and every EC number is empty. % % Parameters % ---------- @@ -48,7 +49,8 @@ ecRxns = p.ecRxns; if ~isfield(model,'eccodes') - error('The model has no model.eccodes field.') + warning('getECfromGEM:noEccodes','The model has no model.eccodes field, no EC numbers are taken from it.') + model.eccodes = repmat({''},numel(model.rxns),1); end %Need to remove the prefix of GECKO light rxn names in the ec structure diff --git a/src/get_enzyme_data/getECstring.m b/src/get_enzyme_data/getECstring.m index 8f4f2e45..e06955d8 100644 --- a/src/get_enzyme_data/getECstring.m +++ b/src/get_enzyme_data/getECstring.m @@ -10,7 +10,8 @@ % EC_set : char % existing EC string to which the EC numbers are appended. % ecNumbers : char -% space-separated EC numbers associated to the protein. +% EC numbers associated to the protein, separated by white space and/or +% semicolons. % % Returns % ------- @@ -25,7 +26,8 @@ % -------- % findECInDB %In case of several ec numbers for the same protein -new_EC_set = replace(strsplit(ecNumbers,' '),';',''); +new_EC_set = regexp(strtrim(ecNumbers),'[;\s]+','split'); +new_EC_set = new_EC_set(~cellfun(@isempty,new_EC_set)); for l = 1:length(new_EC_set) EC_set = [EC_set 'EC' new_EC_set{l}]; if l 4 + writer = 'an unknown release'; + if isfield(model.annotation, 'generator') + writer = model.annotation.generator; + end + error('loadEcModel:format', ['%s has ecModel format %s (written by %s); ' ... + 'this GECKO reads format 4 and older. Update GECKO to load it.'], ... + filename, model.annotation.gecko_format, writer) +end +[model, changed] = upgradeEcModel(model); +if ~isempty(changed) + warning('loadEcModel:upgraded', ['%s has %d protein usage and pool reactions in the GECKO 3 ' ... + 'direction; they are turned forward in the loaded model. upgradeGECKOproject upgrades the ' ... + 'files of the project.'], filename, numel(changed)) +end end diff --git a/src/io/loadFluxData.m b/src/io/loadFluxData.m index 49ec62cb..bd14a404 100644 --- a/src/io/loadFluxData.m +++ b/src/io/loadFluxData.m @@ -19,6 +19,13 @@ % % Notes % ----- +% The function raises an error when the file does not exist +% (loadFluxData:fileNotFound), when a line has a different number of cells +% than the header (loadFluxData:raggedRow) or when the file has no exchange +% flux columns (loadFluxData:noExchangeColumns). An exchange column header has +% the form ' ()'; the reaction id may contain +% parentheses. +% % The fluxData structure has the following fields: % % - conds : sampling condition. @@ -59,21 +66,23 @@ end %Load total protein content and flux data -try - fID = fopen(fluxDataFile); - formatStr = '%s'; - data = textscan(fID,formatStr,'Delimiter','\n'); - fclose(fID); -catch - warning('Failed to load %s.',fluxDataFile); - fluxData = []; - return +if ~isfile(fluxDataFile) + error('loadFluxData:fileNotFound', 'The flux data file %s does not exist.', fluxDataFile); end +fID = fopen(fluxDataFile); +formatStr = '%s'; +data = textscan(fID,formatStr,'Delimiter','\n'); +fclose(fID); fluxDataRaw = []; for i=1:length(data{1}) row = data{1}(i); row = strsplit(row{1},'\t'); row = row(1:end); + if i > 1 && numel(row) ~= size(fluxDataRaw,2) + error('loadFluxData:raggedRow', ... + 'Line %d of %s has %d cells, the header has %d.', ... + i, fluxDataFile, numel(row), size(fluxDataRaw,2)); + end fluxDataRaw = [fluxDataRaw; row]; end if size(fluxDataRaw,2) == 0 @@ -100,9 +109,15 @@ end %Extract observed byProduct names from file +if size(fluxDataRaw,2) < 4 + error('loadFluxData:noExchangeColumns', ... + '%s has no exchange flux columns after the columns condition, Ptot and grRate.', fluxDataFile); +end exchRxns = fluxDataRaw(1,4:end); -exchMets = strtrim(regexprep(exchRxns,'(.*)\(.*\)$','$1')); -exchRxns = regexprep(exchRxns,'.*\((.*)\)$','$1'); +exchMets = exchRxns; +for i=1:numel(exchRxns) + [exchMets{i}, exchRxns{i}] = splitExchHeader(exchRxns{i}); +end fluxData.conds = fluxDataRaw(2:end,1); fluxData.Ptot = str2double(fluxDataRaw(2:end,2)); @@ -112,3 +127,29 @@ fluxData.exchMets = exchMets; fluxData.exchRxnIDs = exchRxns; end + +function [met, rxn] = splitExchHeader(header) +% Split a column header ' ()' at the parenthesis that +% matches the final closing one, so a reaction id may contain parentheses. A +% header of another form gives the whole header as the reaction id. +met = strtrim(header); +rxn = header; +if ~endsWith(header,')') + return +end +depth = 0; +for k=numel(header):-1:1 + if header(k) == ')' + depth = depth + 1; + elseif header(k) == '(' + depth = depth - 1; + if depth == 0 + if k < numel(header)-1 + met = strtrim(header(1:k-1)); + rxn = header(k+1:end-1); + end + return + end + end +end +end diff --git a/src/io/loadProtData.m b/src/io/loadProtData.m index bc3ea4b2..53f10013 100644 --- a/src/io/loadProtData.m +++ b/src/io/loadProtData.m @@ -11,7 +11,9 @@ % replPerCond : double % vector with number of replicates for each condition in the dataset. % Example: [3, 2] if first condition has triplicates and second -% condition has duplicates. +% condition has duplicates. The sum must equal the number of replicate +% columns of the file (all columns after the UniProt ID), otherwise an +% error is raised. % % Name-Value Arguments % -------------------- @@ -109,6 +111,15 @@ if ~isstruct(protDataFile) checkFileExistence(protDataFile); fID = fopen(protDataFile); + nHeaderCols = numel(strsplit(fgetl(fID),'\t','CollapseDelimiters',false)); + if nHeaderCols ~= sum(replPerCond)+1 + fclose(fID); + error('loadProtData:replicateMismatch', ... + ['The header of %s has %d columns but replPerCond sums to %d, ' ... + 'so %d columns are expected (the UniProt ID and one per replicate).'], ... + protDataFile, nHeaderCols, sum(replPerCond), sum(replPerCond)+1) + end + frewind(fID); protDataRaw = textscan(fID,format,'Delimiter','\t','HeaderLines',1,'TreatAsEmpty',{'NA','na','NaN','#VALUE!'}); uniprotIDs = protDataRaw{1}; abundances = cell2mat(protDataRaw(2:end)); @@ -143,16 +154,16 @@ end % Filter by RSD remData = (std(condAbund,0,2,'omitnan')./mean(condAbund,2,'omitnan'))>maxRSD; - condAbund(remData) = nan; + condAbund(remData,:) = nan; % Add stdevs condAbund = mean(condAbund,2,'omitnan')+(addStdevs*std(condAbund,0,2,'omitnan')); % Filter by minVal remData = mean(condAbund,2,'omitnan')' in +% its metaData; an existing description is kept. readYAMLmodel reads the +% metaData description into ecModel.annotation.note, so a note counts as the +% description of the model, as does ecModel.annotation.description. +% % The ecModel is saved to the ecModel-specific models/ subfolder. For % saving to other locations, writeYAMLmodel or exportModel are more % suitable. @@ -14,7 +22,7 @@ function saveEcModel(ecModel,varargin) % Parameters % ---------- % ecModel : struct -% an ecModel in GECKO 3 format (with ecModel.ec structure). +% an ecModel (with ecModel.ec structure). % % Name-Value Arguments % -------------------- @@ -55,8 +63,6 @@ function saveEcModel(ecModel,varargin) end filename = fullfile(params.path,'models',filename); -ecModel.description = ['Enzyme-constrained model of ' ecModel.id]; - switch filename(end-3:end) case {'.xml','sbml'} exportModel(ecModel, filename); @@ -82,6 +88,29 @@ function saveEcModel(ecModel,varargin) fclose('all'); delete('backup.xml'); otherwise % Assume YAML + % The ecModel format the file follows (as project_format in + % model_adapter.toml) and the release that wrote it. + ecModel.annotation.gecko_format = '4'; + ecModel.annotation.generator = ['GECKO ' geckoVersion()]; + hasDescription = false; + for f = {'description', 'note'} + hasDescription = hasDescription || (isfield(ecModel.annotation, f{1}) && ~isempty(ecModel.annotation.(f{1}))); + end + if ~hasDescription + ecModel.annotation.description = ['Enzyme-constrained model of ' ecModel.id]; + end + if isfield(ecModel.annotation, 'geckopy_version') + ecModel.annotation = rmfield(ecModel.annotation, 'geckopy_version'); + end writeYAMLmodel(ecModel,filename); end end + +function v = geckoVersion() +file = fullfile(findGECKOroot, 'version.txt'); +if isfile(file) + v = strtrim(fileread(file)); +else + v = 'unknown'; +end +end diff --git a/src/kcat_tuning/evotune/evotuneScore.m b/src/kcat_tuning/evotune/evotuneScore.m index 71305957..189c4ac9 100644 --- a/src/kcat_tuning/evotune/evotuneScore.m +++ b/src/kcat_tuning/evotune/evotuneScore.m @@ -5,9 +5,7 @@ % tunePriorPenaltyWeight to score one ecModel (with a given set of kcats % already applied via applyKcatConstraints) against the experimental % growth and flux data. Fuses what geckopy splits into simulate.py (the -% FBA half) and distance.py (the RMSE half) into one function, matching -% this module's own predecessor abc_max.m -- there is no MATLAB test -% suite here to benefit from Python's testability-driven split. +% FBA half) and distance.py (the RMSE half) into one function. % % Parameters % ---------- @@ -114,7 +112,7 @@ %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% function [rmse, rmseList] = simulateCondition(ecModel,data,constrain,rxn2block,modelAdapter) % One condition's FBA simulation + carbon-weighted RMSE against measured -% data. Ported from abc_max.m's rmsecal. +% data. rmseList = zeros(length(data.conds),1); diff --git a/src/kcat_tuning/evotune/loadEvotuneData.m b/src/kcat_tuning/evotune/loadEvotuneData.m index c2105b50..85c300ba 100644 --- a/src/kcat_tuning/evotune/loadEvotuneData.m +++ b/src/kcat_tuning/evotune/loadEvotuneData.m @@ -44,19 +44,26 @@ basePath = modelAdapter.params.path; -evoData.fluxData = loadFluxData(fullfile(basePath,'data','evotuneFluxData.tsv'), modelAdapter); +evoData.fluxData = []; +fluxFile = fullfile(basePath,'data','evotuneFluxData.tsv'); +if isfile(fluxFile) + evoData.fluxData = loadFluxData(fluxFile, modelAdapter); +end if ~isempty(evoData.fluxData) evoData.fluxData.biomass = modelAdapter.params.bioRxn; end -evoData.maxGrate = loadFluxData(fullfile(basePath,'data','evotuneMaxGrowth.tsv'), modelAdapter); +evoData.maxGrate = []; +maxGrateFile = fullfile(basePath,'data','evotuneMaxGrowth.tsv'); +if isfile(maxGrateFile) + evoData.maxGrate = loadFluxData(maxGrateFile, modelAdapter); +end if ~isempty(evoData.maxGrate) evoData.maxGrate.biomass = modelAdapter.params.bioRxn; end -% Unlike loadFluxData (used for fluxData/maxGrate above, which already -% degrades to [] on a missing file), readtable has no such guard, so this -% is wrapped explicitly to keep all three files uniformly optional. +% All three files are optional: a missing file gives [] (fluxData, maxGrate) +% or {} (zeroFlux). zeroExchFile = fullfile(basePath,'data','evotuneZeroExch.tsv'); if isfile(zeroExchFile) evoData.zeroFlux = table2cell(readtable(zeroExchFile, 'Delimiter', '\t', 'FileType','delimitedtext')); diff --git a/src/kcat_tuning/evotune/resolveTunableContext.m b/src/kcat_tuning/evotune/resolveTunableContext.m index 28894f14..abddb708 100644 --- a/src/kcat_tuning/evotune/resolveTunableContext.m +++ b/src/kcat_tuning/evotune/resolveTunableContext.m @@ -5,6 +5,12 @@ % Shared by screenKcatLeverage and cmaesKcatTuning so a screen and the % tuning run it feeds are always looking at exactly the same parameters. % +% A kcat belongs to the group whose params.kcatSources entry equals its +% ec.source, or the part of ec.source before ' (' (case-insensitive), so +% 'brenda (wc=0, origin=1)' is in the group of 'brenda' and +% 'combined (sd=0.10, n=2)' in the group of 'combined', with that group's +% sigma0logSource. +% % Parameters % ---------- % ecModel : struct @@ -48,11 +54,14 @@ ecRxnIdsTunable = ecModel.ec.rxns(tunableIdx); kcat0 = ecModel.ec.kcat(tunableIdx); sources = ecModel.ec.source(tunableIdx); +% A source with a detail, such as 'combined (sd=0.10, n=2)', is also matched by +% its name before ' ('. +sourceNames = strtrim(regexprep(sources, ' \(.*$', '')); groups = repmat({'unlabelled'}, numel(tunableIdx), 1); sigma0log = params.sigma0logDefault * ones(numel(tunableIdx),1); for i = 1:numel(params.kcatSources) - idx = strcmpi(sources, params.kcatSources{i}); + idx = strcmpi(sources, params.kcatSources{i}) | strcmpi(sourceNames, params.kcatSources{i}); groups(idx) = params.kcatSources(i); sigma0log(idx) = params.sigma0logSource(i); end diff --git a/src/kcat_tuning/fillCarbonNum.m b/src/kcat_tuning/fillCarbonNum.m index c976ea21..1e177bbe 100644 --- a/src/kcat_tuning/fillCarbonNum.m +++ b/src/kcat_tuning/fillCarbonNum.m @@ -2,7 +2,10 @@ % fillCarbonNum Add a carbon number field to the model. % % Adds a model.excarbon field with the carbon number of each exchange -% reaction, used to weight the RMSE during evotune kcat tuning. +% reaction, used to weight the RMSE during evotune kcat tuning. An exchange +% whose metabolite has no usable formula gets the carbon number 1. A model +% without a metFormulas field, or with only empty formulas, gives every +% exchange the carbon number 1 and a warning (GECKO:fillCarbonNum:noFormulas). % % Parameters % ---------- @@ -17,6 +20,11 @@ % ecModel with an added model.excarbon field. % get carbonnum for each exchange rxn to further calculation of error +if ~isfield(model,'metFormulas') || all(cellfun(@isempty,model.metFormulas)) + warning('GECKO:fillCarbonNum:noFormulas', ... + 'The model has no metabolite formulas; every exchange reaction gets the carbon number 1.') + model.metFormulas = repmat({''},numel(model.mets),1); +end model.excarbon = zeros(length(model.rxns),1); [EXrxn, EXrxnIdx] = getExchangeRxns(model); [CarbonNum,EXfors] = getcarbonnum(model,EXrxn); diff --git a/src/kcat_tuning/sensitivityTuning.m b/src/kcat_tuning/sensitivityTuning.m index 9e0facc2..96d1efce 100644 --- a/src/kcat_tuning/sensitivityTuning.m +++ b/src/kcat_tuning/sensitivityTuning.m @@ -3,7 +3,8 @@ % % Iteratively increases the kcat of whichever enzyme currently limits growth % the most, until the model reaches the desired growth rate, updating the -% tuned values in model.ec.kcat. +% tuned values in model.ec.kcat. The loop also stops, with a warning, when an +% iteration raises growth by less than 1e-9. % % Parameters % ---------- @@ -87,7 +88,10 @@ if isempty(res.x) error('FBA of input model gives no valid result. Reduce protein pool constraint with setProtPoolSize and/or check if exchange constraints are correctly defined.') end -lastGrowth = 0; +% The loop stops when growth rises by less than growthStallTol over the +% previous iteration (the first iteration has nothing to compare with). +lastGrowth = NaN; +growthStallTol = 1e-9; if ~m.ec.geckoLight %for the full model, we first find the draw reaction with the most flux drawRxns = startsWith(m.rxns, 'usage_prot_'); @@ -95,7 +99,11 @@ iteration = 1; while true [res,hs] = solveLP(m,0,[],hs); %skip parsimonius, only takes time - if (lastGrowth == res.f) + if isempty(res.f) + printOrange('WARNING: The model has no feasible solution with the increased kcats, tuning stops.\n'); + break; + end + if ~isnan(lastGrowth) && res.f <= lastGrowth + growthStallTol printOrange('WARNING: No growth increase from increased kcats - check if the constraints on the uptake reactions are too tight.\n'); break; end @@ -113,6 +121,10 @@ drawFluxes(drawRxns) = res.x(drawRxns); % Remove from the list user defined proteins drawFluxes(idxToIgnore) = 0; + if ~any(drawFluxes > 0) + printOrange('WARNING: No protein usage reaction carries flux, tuning cannot continue.\n'); + break; + end [~,sel] = max(drawFluxes); % since bounds 0 to 1000 %Now get the metabolite metSel = m.S(:,sel) > 0; % positive coeff (forward usage) @@ -146,7 +158,11 @@ iteration = 1; while true res = solveLP(m,0); %skip parsimonius, only takes time - if (lastGrowth == res.f) + if isempty(res.f) + printOrange('WARNING: The model has no feasible solution with the increased kcats, tuning stops.\n'); + break; + end + if ~isnan(lastGrowth) && res.f <= lastGrowth + growthStallTol printOrange('No growth increase from increased kcats - check if the constraints on the uptake reactions are too tight.\n'); break; end @@ -162,6 +178,10 @@ %find the highest protein usage flux protPoolStoich = m.S(strcmp(m.mets, 'prot_pool'),:).'; protPoolStoich(idxToIgnore) = 0; + if ~any(res.x .* protPoolStoich < 0) + printOrange('WARNING: No reaction draws on the protein pool, tuning cannot continue.\n'); + break; + end [~,sel] = min(res.x .* protPoolStoich); %max consumption kcatList = [kcatList, sel]; rxn = m.rxns(sel.'); diff --git a/src/kcat_tuning/sigmaFitter.m b/src/kcat_tuning/sigmaFitter.m index 4bff81bc..9ffbfe0c 100644 --- a/src/kcat_tuning/sigmaFitter.m +++ b/src/kcat_tuning/sigmaFitter.m @@ -95,7 +95,14 @@ error = num2str(((growthRate-solution.x(objPos))/growthRate)*100); sigParam = [sigParam; sigma]; end -[~, minIndx] = min(errors); +% Growth that is flat from some sigma on (a target above what the model can +% reach) is returned by the solver with rounding noise. The smallest sigma +% whose growth is within 1e-9 (relative) of the best growth is chosen, so the +% result is the start of the plateau on every solver. The tolerance is +% expressed on the percent error. +[minError, minIndx] = min(errors); +errTol = 1e-9*100*abs(objValues(minIndx))/abs(growthRate); +minIndx = find(errors <= minError + errTol, 1); sigma = sigParam(minIndx); % The loop above leaves the protein pool sized for the *last* sigma tried % (i=100, i.e. sigma=1), not the best-fitting one found by the search -- diff --git a/src/kcat_tuning/truncateValues.m b/src/kcat_tuning/truncateValues.m index f431baeb..f3fb3f47 100644 --- a/src/kcat_tuning/truncateValues.m +++ b/src/kcat_tuning/truncateValues.m @@ -2,7 +2,8 @@ % truncateValues Round values in selected columns to six significant digits. % % Rounds each value in the given columns of a cell array or table to six -% significant digits, based on the value's order of magnitude. +% significant digits, based on the value's order of magnitude. Infinite +% values are returned unchanged. % % Parameters % ---------- @@ -20,6 +21,9 @@ [m,n] = size(table); for i = 1:m for j = cols + if isinf(table{i,j}) + continue + end orderMagn = max([ceil(log10(abs(table{i,j}))),0]); table{i,j} = round(table{i,j},6-orderMagn); end diff --git a/src/limit_proteins/calculateFfactor.m b/src/limit_proteins/calculateFfactor.m index 7cb42764..7cac14fc 100644 --- a/src/limit_proteins/calculateFfactor.m +++ b/src/limit_proteins/calculateFfactor.m @@ -13,9 +13,11 @@ % -------------------- % protData : struct % structure with proteome data, from loadProtData (by default it instead -% attempts to load data/paxDB.tsv). +% attempts to load data/paxDB.tsv). With several samples, the abundance +% of a protein is averaged over the samples in which it is measured. % enzymes : cell -% list of enzymes (default model.ec.enzymes). +% list of enzymes (default model.ec.enzymes). An empty cell array {} +% means no enzymes (f is 0); [] means the default. % modelAdapter : ModelAdapter % a loaded model adapter (default: the current default model adapter). % @@ -50,7 +52,7 @@ end params = modelAdapter.getParameters(); -if isempty(enzymes) +if isnumeric(enzymes) && isempty(enzymes) enzymes = model.ec.enzymes; end @@ -99,7 +101,7 @@ protData.abundances = protData.level .* protData.MW; end -avgAbundances = mean(protData.abundances,2); +avgAbundances = mean(protData.abundances,2,'omitnan'); totalProt = sum(avgAbundances,'omitnan'); % Get enzymes in model diff --git a/src/limit_proteins/constrainEnzConcs.m b/src/limit_proteins/constrainEnzConcs.m index 5029b400..75b90385 100644 --- a/src/limit_proteins/constrainEnzConcs.m +++ b/src/limit_proteins/constrainEnzConcs.m @@ -25,7 +25,8 @@ % % Notes % ----- -% To populate model.ec.concs you should run fillEnzConcs. +% A negative concentration in model.ec.concs is contradictory data and +% raises the error constrainEnzConcs:negativeConcentration. To populate model.ec.concs you should run fillEnzConcs. % % Examples % -------- @@ -63,6 +64,11 @@ protCons = []; else protCons = ~isnan(model.ec.concs); + if any(model.ec.concs(protCons) < 0) + error('constrainEnzConcs:negativeConcentration', ... + 'model.ec.concs has a negative concentration for %s.', ... + strjoin(model.ec.enzymes(model.ec.concs < 0), ', ')) + end end %Set all reactions to draw from prot_pool (forward: prot_pool -> prot_) diff --git a/src/limit_proteins/constrainFluxData.m b/src/limit_proteins/constrainFluxData.m index fc10d369..fa998c05 100644 --- a/src/limit_proteins/constrainFluxData.m +++ b/src/limit_proteins/constrainFluxData.m @@ -27,7 +27,8 @@ % 'max' if the provided growth rate should be set as maximum growth rate % (= upper bound), or 'min' if it should be set as minimum growth rate % (= lower bound). The latter option is suitable if minimization of -% prot_pool_exchange is used as objective function (default 'max'). +% prot_pool_exchange is used as objective function (default 'max'). Any +% other value raises constrainFluxData:invalidMaxMinGrowth. % looseStrictFlux : char or double % how strictly constrained the exchange fluxes should be (default % 'loose'): @@ -49,6 +50,10 @@ % % Notes % ----- +% An exchange reaction in fluxData.exchRxnIDs that is not in the model +% raises constrainFluxData:missingReaction, and a condition that is not in +% fluxData.conds raises constrainFluxData:unknownCondition. +% % If a provided constraint is either -1000 or 1000, then the function will % update the reaction lower and upper bound to either allow uptake or % excretion, irrespective of what option is given as the looseStrictFlux @@ -96,12 +101,24 @@ fluxData = loadFluxData(fullfile(params.path,'data','fluxData.tsv'),modelAdapter); end +if ~(ischar(maxMinGrowth) && any(strcmp(maxMinGrowth, {'max','min'}))) + error('constrainFluxData:invalidMaxMinGrowth', ... + 'maxMinGrowth must be ''max'' or ''min''.') +end + +missingRxns = fluxData.exchRxnIDs(~ismember(fluxData.exchRxnIDs, model.rxns)); +if ~isempty(missingRxns) + error('constrainFluxData:missingReaction', ... + 'The exchange reactions %s of fluxData are not in the model.', strjoin(missingRxns, ', ')) +end + if isempty(condition) condition = 1; elseif ~isnumeric(condition) idx = find(strcmp(fluxData.conds,condition)); - if isempty(condition) - error(['Condition ' condition ' cannot be found in fluxData']) + if isempty(idx) + error('constrainFluxData:unknownCondition', ... + 'Condition %s cannot be found in fluxData.', condition) else condition = idx; end diff --git a/src/limit_proteins/fillEnzConcs.m b/src/limit_proteins/fillEnzConcs.m index 501567ed..6353d012 100644 --- a/src/limit_proteins/fillEnzConcs.m +++ b/src/limit_proteins/fillEnzConcs.m @@ -32,6 +32,9 @@ % % Notes % ----- +% A negative abundance of a protein that is an enzyme of the model is +% contradictory data and raises the error fillEnzConcs:negativeAbundance. +% % To also constrain the model with the content of model.ec.concs, you should % run constrainEnzConcs. % @@ -57,5 +60,10 @@ model.ec.concs=nan(numel(model.ec.enzymes),1); [a,b] = ismember(uniprotIDs, model.ec.enzymes); +if any(abundances(a) < 0) + error('fillEnzConcs:negativeAbundance', ... + 'protData has a negative abundance for %s.', ... + strjoin(uniprotIDs(a & abundances < 0), ', ')) +end model.ec.concs(b(a)) = abundances(a); end diff --git a/src/limit_proteins/flexibilizeEnzConcs.m b/src/limit_proteins/flexibilizeEnzConcs.m index 2e3cf062..b94e5d57 100644 --- a/src/limit_proteins/flexibilizeEnzConcs.m +++ b/src/limit_proteins/flexibilizeEnzConcs.m @@ -39,6 +39,17 @@ % a loaded model adapter (default: the current default model adapter). % verbose : logical % whether progress should be reported (default true). +% perComplex : logical +% whether every complex (see getComplexFamilies) is flexibilized as one +% enzyme (default false). Enzymes and complexes are then ranked by the +% growth gained per foldChange of raising all their usage upper bounds +% together (a levelled complex binds on all subunits at once, so no +% single subunit shows a gain), every measured subunit of the picked +% complex is raised by the same factor, iterations are counted per +% complex, and one factor per complex is kept in the final pass, so that +% concentrations levelled by levelComplexConcs stay levelled. An upper +% bound is never lowered below its current value. The frequence of a +% complex is recorded on its first measured subunit. % % Returns % ------- @@ -66,23 +77,28 @@ % % See also % -------- -% constrainEnzConcs, getConcControlCoeffs +% constrainEnzConcs, getConcControlCoeffs, levelComplexConcs, getComplexFamilies p = parseGECKOargs(varargin, { ... 'expGrowth', []; ... 'foldChange', []; ... 'iterPerEnzyme', []; ... 'modelAdapter', []; ... - 'verbose', []}); + 'verbose', []; ... + 'perComplex', []}); expGrowth = p.expGrowth; foldChange = p.foldChange; iterPerEnzyme = p.iterPerEnzyme; modelAdapter = p.modelAdapter; verbose = p.verbose; +perComplex = p.perComplex; if isempty(verbose) verbose = true; end +if isempty(perComplex) + perComplex = false; +end if isempty(modelAdapter) modelAdapter = ModelAdapterManager.getDefault(); if isempty(modelAdapter) @@ -134,6 +150,12 @@ % Store how many time is predicted a enzyme with the highest coeff frequence = zeros(numel(proteins),1); +if perComplex + [model, flexEnz] = flexibilizePerComplex(model, proteins, protConcs, ... + predGrowth, expGrowth, foldChange, iterPerEnzyme, params, verbose); + return +end + flexBreak=false; if any(protConcs) while predGrowth < expGrowth @@ -265,3 +287,249 @@ flexEnz.flexConcs = flexEnz.flexConcs(b); flexEnz.frequence = flexEnz.frequence(b); end + +function [model, flexEnz] = flexibilizePerComplex(model, proteins, protConcs, predGrowth, expGrowth, foldChange, iterPerEnzyme, params, verbose) +% Flexibilize with every complex as one unit, see the perComplex option. +if isempty(protConcs) + error('Protein concentrations have not been defined. Please run readProteomics and constrainEnzConcs') +end +limit = 0.75; +nProt = numel(proteins); +[~, usageIdx] = ismember(strcat('usage_prot_', proteins), model.rxns); +bioRxnIdx = getIndexes(model, params.bioRxn, 'rxns'); +families = getComplexFamilies(model); + +% Positions in proteins of each unit that is relaxed together: the measured +% subunits that belong to a complex, or a single enzyme +units = {}; +assigned = false(nProt, 1); +for i = 1:nProt + if assigned(i) + continue + end + [~, e] = ismember(proteins{i}, model.ec.enzymes); + c = families.owner(e); + members = i; + if c > 0 + cplx = families.complexes{c}; + [~, members] = ismember(cplx.enzymes(cplx.owned), proteins); + members = members(members > 0)'; + end + assigned(members) = true; + units{end+1, 1} = members; %#ok +end +unitFrequence = zeros(numel(units), 1); +frequence = zeros(nProt, 1); +touched = false(nProt, 1); + +% Backstop on the iterations when the number per unit is not limited +if isinf(iterPerEnzyme) + capPerEnzyme = 1000; +else + capPerEnzyme = iterPerEnzyme; +end +maxTotalIter = nProt * capPerEnzyme + nProt; +iterCount = 0; +flexBreak = false; +changedProtPool = false; + +while predGrowth < expGrowth + iterCount = iterCount + 1; + if iterCount > maxTotalIter + printOrange(['WARNING: The global iteration limit has been reached without reaching expGrowth. ' ... + 'The target may be unreachable even with relaxed enzyme bounds.\n']); + flexBreak = true; + break + end + scores = getUnitScores(model, usageIdx, units, foldChange, limit); + + if ~any(scores > 0) + disp('No (more) limiting enzymes have been found. Attempting to increase protein pool exchange...') + protPoolIdx = getIndexes(model,'prot_pool_exchange','rxns'); + oldProtPool = model.ub(protPoolIdx); + tempModel = setParam(model,'ub',protPoolIdx,1000); + tempModel = setParam(tempModel,'ub',bioRxnIdx,expGrowth); + sol = solveLP(tempModel); + if (sol.f-predGrowth)>1e-3 + predGrowth = sol.f; + tempModel = setParam(tempModel,'lb',bioRxnIdx,predGrowth); + tempModel = setParam(tempModel,'obj',protPoolIdx,-1); + sol = solveLP(tempModel); + newProtPool = sol.x(protPoolIdx); + model.ub(protPoolIdx) = newProtPool; + fprintf(['Changing the upper bound of protein pool exchange from %s ',... + 'to %s enabled a\ngrowth rate of %s. It can be helpful to set ', ... + 'the upper bound of protein\npool exchange to 1000 before ',... + 'running flexibilizeEnzConcs.\n'],num2str(oldProtPool), ... + num2str(newProtPool),num2str(predGrowth)); + changedProtPool = true; + else + fprintf(['Protein pool exchange was also not limiting. Inability to reach growth ',... + 'rate is not related to\nenzyme constraints. Maximum growth rate ',... + 'is %s.\n'], num2str(predGrowth)) + end + expGrowth = predGrowth; + break + end + + [~, unit] = max(scores); + members = units{unit}; + frequence(members(1)) = frequence(members(1)) + 1; + unitFrequence(unit) = unitFrequence(unit) + 1; + if unitFrequence(unit) > iterPerEnzyme + if numel(members) > 1 + what = ['complex of ' strjoin(proteins(members)', ', ')]; + else + what = ['Protein ' proteins{members(1)}]; + end + printOrange(['WARNING: Limit has been reached. ' what ' seems to be problematic. Consider changing the kcat.\n']); + flexBreak = true; + break + end + + increase = foldChange * unitFrequence(unit); + for i = members + touched(i) = true; + model.ub(usageIdx(i)) = max(model.ub(usageIdx(i)), model.ec.concs(protConcs(i)) * (1+increase)); + end + sol = solveLP(model); + if sol.stat == 1 + predGrowth = sol.f; + else + predGrowth = 0; + end + if verbose + disp(['Protein ' proteins{members(1)} ' UB adjusted. Grow: ' num2str(predGrowth)]) + end +end + +flexIdx = find(frequence > 0 | touched); +protFlex = proteins(flexIdx); +oldConcs = model.ec.concs(protConcs(flexIdx)); +freq = frequence(flexIdx); +if isempty(flexIdx) + flexConcs = zeros(0, 1); +elseif flexBreak + flexConcs = model.ub(usageIdx(flexIdx)); +else + % Not all flexibilized proteins require flexibilization in the end. + % Test flux distribution with minimum prot_pool usage + modelTemp = setParam(model,'var',params.bioRxn,expGrowth,0.5); + modelTemp = setParam(modelTemp,'obj','prot_pool_exchange',-1); + sol = solveLP(modelTemp,1); + newConcs = abs(sol.x(usageIdx(flexIdx))); + % One factor per complex: every flexibilized subunit takes the largest + % new/old of its complex + seen = false(numel(flexIdx), 1); + for k = 1:numel(flexIdx) + if seen(k) + continue + end + [~, e] = ismember(protFlex{k}, model.ec.enzymes); + c = families.owner(e); + group = k; + if c > 0 + cplx = families.complexes{c}; + [~, group] = ismember(cplx.enzymes(cplx.owned), protFlex); + group = group(group > 0)'; + end + seen(group) = true; + if numel(group) < 2 + continue + end + withOld = group(oldConcs(group) > 0); + if isempty(withOld) + continue + end + factor = max(newConcs(withOld) ./ oldConcs(withOld)); + newConcs(withOld) = oldConcs(withOld) * factor; + end + keepOld = newConcs < oldConcs; + model.ub(usageIdx(flexIdx(keepOld))) = oldConcs(keepOld); + model.ub(usageIdx(flexIdx(~keepOld))) = newConcs(~keepOld); + protFlex(keepOld) = []; + oldConcs(keepOld) = []; + freq(keepOld) = []; + flexConcs = newConcs(~keepOld); +end + +flexEnz.uniprotIDs = protFlex; +flexEnz.oldConcs = oldConcs; +flexEnz.flexConcs = flexConcs; +flexEnz.frequence = freq; +if changedProtPool + flexEnz.uniprotIDs(end+1) = {'prot_pool'}; + flexEnz.oldConcs(end+1) = oldProtPool; + flexEnz.flexConcs(end+1) = newProtPool; + flexEnz.frequence(end+1) = 1; +end +flexEnz.ratioIncr = flexEnz.flexConcs./flexEnz.oldConcs; +[~,b] = sort(flexEnz.ratioIncr,'descend'); +flexEnz.ratioIncr = flexEnz.ratioIncr(b); +flexEnz.uniprotIDs = flexEnz.uniprotIDs(b); +flexEnz.oldConcs = flexEnz.oldConcs(b); +flexEnz.flexConcs = flexEnz.flexConcs(b); +flexEnz.frequence = flexEnz.frequence(b); +end + +function scores = getUnitScores(model, usageIdx, units, foldChange, limit) +% Growth gained per fold of raising the usage upper bounds of each unit +% together. With reduced costs, the sum over the unit's subunits that run +% above limit of their cap of |reduced cost of the usage reaction| times its +% upper bound. Unlike the shadow price of the protein metabolite, the +% reduced cost of the usage reaction leaves out the price of the protein +% pool, which would otherwise be counted once per subunit. When no such +% score is positive (no reduced costs, or the protein pool binds and the +% solver puts the whole price on it), the candidate units are probed one by +% one with all their upper bounds raised by foldChange and the pool lifted. +scores = zeros(numel(units), 1); +sol = solveLP(model); +if sol.stat ~= 1 + return +end +candidates = zeros(0, 1); +active = cell(numel(units), 1); +for k = 1:numel(units) + rx = usageIdx(units{k}); + ub = model.ub(rx); + act = ub > 0; + act(act) = sol.x(rx(act)) ./ ub(act) > limit; + if any(act) + candidates(end+1, 1) = k; %#ok + active{k} = rx(act); + end +end +if isempty(candidates) + return +end +needed = vertcat(active{candidates}); +if ~isempty(sol.rCost) && all(isfinite(sol.rCost(needed))) + for k = candidates' + scores(k) = sum(abs(sol.rCost(active{k})) .* model.ub(active{k})); + end + scores(scores < 1e-12) = 0; + if any(scores > 0) + return + end + scores = zeros(numel(units), 1); +end +poolIdx = getIndexes(model, 'prot_pool_exchange', 'rxns'); +model.ub(poolIdx) = max(model.ub(poolIdx), 1000); +base = solveLP(model); +if base.stat ~= 1 + return +end +for k = candidates' + tempModel = model; + rx = usageIdx(units{k}); + tempModel.ub(rx) = tempModel.ub(rx) * foldChange; + probe = solveLP(tempModel); + if probe.stat == 1 + gain = probe.f - base.f; + if gain > 1e-3 + scores(k) = gain / (foldChange - 1); + end + end +end +end + diff --git a/src/limit_proteins/getComplexFamilies.m b/src/limit_proteins/getComplexFamilies.m new file mode 100644 index 00000000..f7a27c6c --- /dev/null +++ b/src/limit_proteins/getComplexFamilies.m @@ -0,0 +1,198 @@ +function families = getComplexFamilies(model, varargin) +% getComplexFamilies Group the enzymes of multi-subunit reactions into complexes. +% +% A complex is a set of enzymes that catalyses a reaction together, taken +% from model.ec.rxnEnzMat. Two enzyme sets are one complex when they share +% at least minShared subunits and at least a fraction minOverlap of the +% larger set (isozyme variants that swap a subunit, the same complex on +% different reactions). A single shared protein never merges two sets, so +% electron carriers and shared subunits (cytochrome c, thioredoxin, the E3 +% subunit of the 2-oxo-acid dehydrogenases) do not chain unrelated +% complexes together. +% +% A subunit in exactly two complexes belongs to the one whose enzyme sets +% catalyse more reactions (the core subunits COX1-3 of complex IV also +% appear in one assembly reaction). A subunit in three or more complexes, +% in two with equal weight, or that also catalyses a reaction on its own is +% shared: it is left as measured and does not take part in the summary of a +% complex. +% +% When isozyme variants of a complex disagree on the number of copies of a +% subunit, the first variant is used and a warning is given. +% +% Parameters +% ---------- +% model : struct +% an ecModel in GECKO 3 format (with ecModel.ec structure), with +% ec.rxnEnzMat (copies per subunit). +% +% Name-Value Arguments +% -------------------- +% minOverlap : double +% two enzyme sets are one complex when they share at least this +% fraction of the larger set's subunits (default 0.5)... +% minShared : double +% ...and at least this many subunits (default 2). +% +% Returns +% ------- +% families : struct +% the complexes of the model, with the fields: +% +% - complexes : cell array with one struct per complex, with the fields +% enzymes (cell array with every subunit that appears in any of its +% enzyme sets), copies (copies of each of these subunits) and owned +% (logical, true for the subunits that belong to this complex). +% - owner : numeric vector with one entry per model.ec.enzymes, the +% index in complexes of the complex that the subunit belongs to, or 0 +% if it belongs to none. +% - shared : cell array with the subunits of a complex that belong to +% none: carriers and subunits shared between complexes. +% +% Examples +% -------- +% % optional arguments may be given positionally or as name-value pairs: +% families = getComplexFamilies(model); +% families = getComplexFamilies(model, 'minShared', 3); +% +% See also +% -------- +% levelComplexConcs, flexibilizeEnzConcs + +p = parseGECKOargs(varargin, { ... + 'minOverlap', []; ... + 'minShared', []}); +minOverlap = p.minOverlap; +minShared = p.minShared; +if isempty(minOverlap); minOverlap = 0.5; end +if isempty(minShared); minShared = 2; end + +if ~isfield(model, 'ec') || ~isfield(model.ec, 'rxnEnzMat') || isempty(model.ec.rxnEnzMat) + error('getComplexFamilies:noRxnEnzMat', ... + 'The model has no ec.rxnEnzMat. Run makeEcModel first.') +end +enzymes = model.ec.enzymes; +matrix = sparse(model.ec.rxnEnzMat); + +% Distinct enzyme sets of the reactions with more than one enzyme, in order +% of first appearance, with the copies of the first reaction that has the set +setIdx = {}; +setCopies = {}; +setCount = zeros(0, 1); +setLookup = containers.Map('KeyType', 'char', 'ValueType', 'double'); +alone = false(numel(enzymes), 1); +for row = 1:size(matrix, 1) + [~, cols, vals] = find(matrix(row, :)); + if numel(cols) == 1 + alone(cols) = true; + elseif ~isempty(cols) + key = sprintf('%d,', cols); + if isKey(setLookup, key) + k = setLookup(key); + else + k = numel(setIdx) + 1; + setLookup(key) = k; + setIdx{k, 1} = cols(:); + setCopies{k, 1} = full(vals(:)); + setCount(k, 1) = 0; + end + setCount(k) = setCount(k) + 1; + end +end + +% Merge the enzyme sets that overlap enough +nSets = numel(setIdx); +parent = 1:nSets; +byEnzyme = cell(numel(enzymes), 1); +for i = 1:nSets + for e = setIdx{i}' + byEnzyme{e}(end+1) = i; + end +end +for e = 1:numel(byEnzyme) + indices = byEnzyme{e}; + for x = 1:numel(indices) + for y = x+1:numel(indices) + i = indices(x); + j = indices(y); + common = numel(intersect(setIdx{i}, setIdx{j})); + if common >= minShared && common >= minOverlap * max(numel(setIdx{i}), numel(setIdx{j})) + parent(findRoot(parent, i)) = findRoot(parent, j); + end + end + end +end +roots = zeros(1, nSets); +for i = 1:nSets + roots(i) = findRoot(parent, i); +end + +% One complex per group of sets, numbered by the first set of the group +[groupRoots, ~, groupOf] = unique(roots, 'stable'); +nComplex = numel(groupRoots); +complexes = cell(nComplex, 1); +weight = cell(nComplex, 1); +for g = 1:nComplex + idx = zeros(0, 1); + copies = zeros(0, 1); + w = zeros(numel(enzymes), 1); + for i = find(groupOf(:)' == g) + w(setIdx{i}) = w(setIdx{i}) + setCount(i); + for n = 1:numel(setIdx{i}) + e = setIdx{i}(n); + pos = find(idx == e, 1); + if isempty(pos) + idx(end+1, 1) = e; %#ok + copies(end+1, 1) = setCopies{i}(n); %#ok + elseif copies(pos) ~= setCopies{i}(n) + warning('getComplexFamilies:copiesDisagree', ... + '%s has %g copies in one variant and %g in another; the first is used.', ... + enzymes{e}, copies(pos), setCopies{i}(n)) + end + end + end + complexes{g} = struct('enzymes', {enzymes(idx)}, 'copies', copies, 'idx', idx); + weight{g} = w; +end + +% A subunit belongs to the complex with most reactions when it is in two +owner = zeros(numel(enzymes), 1); +inComplex = false(numel(enzymes), 1); +for e = 1:numel(enzymes) + hits = []; + for g = 1:nComplex + if weight{g}(e) > 0 + hits(end+1, :) = [weight{g}(e), g]; %#ok + end + end + if isempty(hits) + continue + end + inComplex(e) = true; + if alone(e) || size(hits, 1) > 2 + continue + end + if size(hits, 1) == 1 + owner(e) = hits(1, 2); + elseif hits(1, 1) ~= hits(2, 1) + [~, best] = max(hits(:, 1)); + owner(e) = hits(best, 2); + end +end +for g = 1:nComplex + complexes{g}.owned = owner(complexes{g}.idx) == g; + complexes{g} = rmfield(complexes{g}, 'idx'); +end + +families.complexes = complexes; +families.owner = owner; +families.shared = enzymes(inComplex & owner == 0); +end + +function r = findRoot(parent, i) +% Root of the union-find tree that contains i +r = i; +while parent(r) ~= r + r = parent(r); +end +end diff --git a/src/limit_proteins/levelComplexConcs.m b/src/limit_proteins/levelComplexConcs.m new file mode 100644 index 00000000..9b927996 --- /dev/null +++ b/src/limit_proteins/levelComplexConcs.m @@ -0,0 +1,132 @@ +function [model, result] = levelComplexConcs(model, varargin) +% levelComplexConcs Give every enzyme complex one abundance. +% +% Absolute proteomics recovers the subunits of a complex unevenly, so after +% fillEnzConcs the subunits of one complex can disagree several fold about +% how much of it there is. Capped one by one, the complex can then carry no +% more flux than its least abundant subunit allows. This function groups +% the enzymes of every multi-subunit reaction into complexes (see +% getComplexFamilies) and gives each complex one abundance, scaled to every +% subunit by its stoichiometry. +% +% Run after fillEnzConcs and before constrainEnzConcs. The concentrations +% (mg/gDCW) in model.ec.concs are converted to molar amounts with model.ec.mw +% for the levelling and back afterwards. Per complex, the statistic over the +% measured subunits that belong to the complex of the molar amount divided +% by the copies of the subunit is written back, times the copies and the +% molecular weight, to every subunit that belongs to the complex. Subunits +% that are shared between complexes, or that also catalyse a reaction on +% their own, are left as measured. +% +% Parameters +% ---------- +% model : struct +% an ecModel in GECKO 3 format (with ecModel.ec structure), with +% ec.concs filled. +% +% Name-Value Arguments +% -------------------- +% statistic : char +% the summary over the measured subunits, 'median' or 'mean' (default +% 'median'). +% fillMissing : logical +% whether subunits without a measurement, that belong to a complex, are +% given the concentration of the complex (default true). +% families : struct +% the complexes of the model, as returned by getComplexFamilies +% (default: calculated from the model). +% +% Returns +% ------- +% model : struct +% ecModel where model.ec.concs has one abundance per complex. +% result : struct +% what was changed, with the fields: +% +% - adjusted : cell array with the measured subunits whose +% concentration was replaced by that of the complex. +% - added : cell array with the unmeasured subunits that were given the +% concentration of the complex. +% - shared : cell array with the measured subunits that were left as +% measured because they belong to more than one complex or also +% catalyse a reaction on their own. +% - skipped : cell array with one cell array of subunits per complex +% that has no measured subunit that belongs to it. +% +% Examples +% -------- +% % optional arguments may be given positionally or as name-value pairs: +% model = levelComplexConcs(model); +% model = levelComplexConcs(model, 'statistic', 'mean'); +% [model, result] = levelComplexConcs(model, 'fillMissing', false); +% +% See also +% -------- +% getComplexFamilies, fillEnzConcs, constrainEnzConcs, flexibilizeEnzConcs + +p = parseGECKOargs(varargin, { ... + 'statistic', []; ... + 'fillMissing', []; ... + 'families', []}); +statistic = p.statistic; +fillMissing = p.fillMissing; +families = p.families; +if isempty(statistic); statistic = 'median'; end +if isempty(fillMissing); fillMissing = true; end +statistic = char(statistic); +if ~ismember(statistic, {'median','mean'}) + error('levelComplexConcs:statistic', ... + 'statistic must be ''mean'' or ''median'', not ''%s''.', statistic) +end +summarise = str2func(statistic); +if isempty(families) + families = getComplexFamilies(model); +end + +if ~isfield(model.ec, 'concs') || numel(model.ec.concs) ~= numel(model.ec.enzymes) + error('levelComplexConcs:noConcs', ... + 'model.ec.concs has no entry per enzyme. Run fillEnzConcs first.') +end +enzymes = model.ec.enzymes; +mw =model.ec.mw(:); +concs = model.ec.concs(:); +molar = concs ./ mw; + +% Measured amounts by enzyme: finite entries, in order of the enzymes +values = molar; +isKnown = isfinite(molar); +isLevel = isKnown & molar > 0; +result.adjusted = cell(0, 1); +result.added = cell(0, 1); +result.shared = sort(enzymes(ismember(enzymes, families.shared) & isKnown)); +result.skipped = cell(0, 1); + +for c = 1:numel(families.complexes) + cplx = families.complexes{c}; + [~, pos] = ismember(cplx.enzymes, enzymes); + owned = find(cplx.owned); + ownedPos = pos(owned); + measured = isLevel(ownedPos); + if ~any(measured) + result.skipped{end+1, 1} = sort(cplx.enzymes(:))'; %#ok + continue + end + perCopy = summarise(values(ownedPos(measured)) ./ cplx.copies(owned(measured))); + for n = 1:numel(owned) + e = ownedPos(n); + level = perCopy * cplx.copies(owned(n)); + if isLevel(e) + if abs(values(e) - level) > 1e-8 + 1e-5 * abs(level) + result.adjusted{end+1, 1} = enzymes{e}; %#ok + end + values(e) = level; + elseif fillMissing + values(e) = level; + isKnown(e) = true; + result.added{end+1, 1} = enzymes{e}; %#ok + end + end +end + +model.ec.concs(isKnown) = values(isKnown) .* mw(isKnown); +end diff --git a/src/limit_proteins/relaxProteomicsGreedy.m b/src/limit_proteins/relaxProteomicsGreedy.m index 91a3df49..60171c3c 100644 --- a/src/limit_proteins/relaxProteomicsGreedy.m +++ b/src/limit_proteins/relaxProteomicsGreedy.m @@ -19,7 +19,9 @@ % target objective value. Required. % enzymeSet : cell % subset of uniprot ids eligible for relaxation (default: every -% currently proteomics-constrained enzyme). +% currently proteomics-constrained enzyme). An empty cell array {} means +% no enzyme is eligible (converged is false unless the model already +% reaches minimalGrowth); [] means the default. % maxIterations : double % safety cap; errors if exceeded while eligible enzymes still remained % (default 100). @@ -91,7 +93,7 @@ error('Cannot find prot_ metabolites for all enzymes. This is done by makeEcModel.') end -if isempty(enzymeSet) +if isnumeric(enzymeSet) && isempty(enzymeSet) pool = model.ec.enzymes; else pool = intersect(enzymeSet(:), model.ec.enzymes, 'stable'); diff --git a/src/model_adapter/ModelAdapter.m b/src/model_adapter/ModelAdapter.m index e70a9ded..182cdc8a 100644 --- a/src/model_adapter/ModelAdapter.m +++ b/src/model_adapter/ModelAdapter.m @@ -62,16 +62,29 @@ end function folder = getBrendaDBFolder(obj) - folder = fullfile(findGECKOroot(),'databases'); + % The project's data/brenda (geckopy brenda-refresh writes + % there) when it exists, otherwise GECKO's BRENDA release, + % downloaded once (fetchBrendaAsset). + folder = fullfile(obj.params.path,'data','brenda'); + if ~isfolder(folder) + folder = fetchBrendaAsset(); + end end function x = getPhylDistStructPath(obj) - % RAVEN 3 keeps keggPhylDist.mat under reconstruction/kegg, - % RAVEN 2 under external/kegg. + % RAVEN 3 keeps keggPhylDist.mat under src/reconstruction/kegg + % (earlier versions of RAVEN 3 under reconstruction/kegg), RAVEN + % 2 under external/kegg. ravenRoot = findRAVENroot(); - x = fullfile(ravenRoot,'reconstruction','kegg','keggPhylDist.mat'); - if ~isfile(x) - x = fullfile(ravenRoot,'external','kegg','keggPhylDist.mat'); + candidates = {fullfile(ravenRoot,'src','reconstruction','kegg','keggPhylDist.mat'), ... + fullfile(ravenRoot,'reconstruction','kegg','keggPhylDist.mat'), ... + fullfile(ravenRoot,'external','kegg','keggPhylDist.mat')}; + x = candidates{end}; + for i = 1:numel(candidates) + if isfile(candidates{i}) + x = candidates{i}; + break + end end end diff --git a/src/model_adapter/ModelAdapterManager.m b/src/model_adapter/ModelAdapterManager.m index e50fcdc1..a75b0caa 100644 --- a/src/model_adapter/ModelAdapterManager.m +++ b/src/model_adapter/ModelAdapterManager.m @@ -4,6 +4,10 @@ % stores a process-wide default adapter, so that GECKO functions can % retrieve the active adapter without it being passed explicitly. % +% An adapter is loaded from model_adapter.toml (give the file or the +% project folder; see TomlAdapter) or from an adapter class (give its .m +% file). +% % Notes % ----- % All methods are static. The default adapter is held in a persistent @@ -20,9 +24,22 @@ end ModelAdapterManager.showGECKO4Notice(); + adapterPath = char(adapterPath); + if isfolder(adapterPath) + tomlFile = fullfile(adapterPath, 'model_adapter.toml'); + if ~isfile(tomlFile) + error('No model_adapter.toml found in %s.', adapterPath); + end + adapter = TomlAdapter(tomlFile); + return + end [adapterFolder, adapterClassName, extension] = fileparts(adapterPath); - if ~strcmp(extension, '.m') - error('Please provide the full path to the adapter file, including the file extension.'); + if strcmp(extension, '.toml') + adapter = TomlAdapter(adapterPath); + return + elseif ~strcmp(extension, '.m') + error(['Please provide the project folder, its model_adapter.toml, or the ' ... + 'full path to the adapter class file, including the .m extension.']); else s = pathsep; pathStr = [s, path, s]; diff --git a/src/model_adapter/TomlAdapter.m b/src/model_adapter/TomlAdapter.m new file mode 100644 index 00000000..28b7fef0 --- /dev/null +++ b/src/model_adapter/TomlAdapter.m @@ -0,0 +1,113 @@ +% TomlAdapter Model adapter configured by model_adapter.toml. +% +% The model adapter for a project whose parameters are in +% model_adapter.toml, the configuration file that GECKO and geckopy share. +% No adapter class has to be written: what used to be code in an adapter +% class is set in the TOML file. +% +% - Spontaneous reactions: [spontaneous] name_contains (reactions whose +% name contains the text) and/or file (a TSV of reaction identifiers, +% optionally with a second 0/1 column). +% - Anaerobic conditions and protein content during kcat tuning: +% [matlab] make_model_anaerobic and change_protein_biomass name MATLAB +% functions, for instance in the project's code folder, which is added +% to the MATLAB path. Each takes the ecModel (and, for +% change_protein_biomass, the protein content) and returns the ecModel. +% +% A project that needs other custom code can keep an adapter class and +% read its parameters from the TOML file in its constructor: +% +% obj.params = loadAdapterParams(fullfile(projectPath,'model_adapter.toml')); +% +% Examples +% -------- +% adapter = TomlAdapter(fullfile(projectPath,'model_adapter.toml')); +% % or, as the default adapter: +% ModelAdapterManager.setDefault(projectPath); +% +% See also +% -------- +% ModelAdapter, ModelAdapterManager, loadAdapterParams, convertAdapterToToml +classdef TomlAdapter < ModelAdapter + methods + function obj = TomlAdapter(tomlFile) + % TomlAdapter Load the adapter from model_adapter.toml. + % + % Parameters + % ---------- + % tomlFile : char + % path to model_adapter.toml, or to the project folder that + % holds it. + obj.params = loadAdapterParams(tomlFile); + codeFolder = fullfile(obj.params.path, 'code'); + if isfolder(codeFolder) + addpath(codeFolder); + end + end + + function [spont,spontRxnNames] = getSpontaneousReactions(obj,model) + % getSpontaneousReactions Reactions set as spontaneous in [spontaneous]. + % + % Returns + % ------- + % spont : logical + % true for each reaction of model that is spontaneous. + % spontRxnNames : cell + % identifiers of those reactions. + spont = false(numel(model.rxns),1); + if isfield(obj.params,'spontaneous') + s = obj.params.spontaneous; + if isfield(s,'name_contains') && ~isempty(s.name_contains) + spont = spont | contains(model.rxnNames, s.name_contains); + end + if isfield(s,'file') && ~isempty(s.file) + spont = spont | ismember(model.rxns, readSpontaneousFile(s.file)); + end + end + spontRxnNames = model.rxns(spont); + end + + function ecModel = makeModelAnaerobic(obj,ecModel) + % makeModelAnaerobic Run the function named in [matlab] make_model_anaerobic. + fun = hookName(obj, 'makeModelAnaerobic'); + if ~isempty(fun) + ecModel = feval(fun, ecModel); + end + end + + function ecModel = changeProteinBiomass(obj,ecModel,Ptot) + % changeProteinBiomass Run the function named in [matlab] change_protein_biomass. + fun = hookName(obj, 'changeProteinBiomass'); + if ~isempty(fun) + ecModel = feval(fun, ecModel, Ptot); + end + end + end +end + +function fun = hookName(obj, field) +fun = ''; +if isfield(obj.params,'matlab') && isfield(obj.params.matlab, field) + fun = obj.params.matlab.(field); +end +end + +function rxns = readSpontaneousFile(file) +% Reaction identifiers in the first column; with a second column, only +% rows where it is 1 or true. The first row is a header. +fid = fopen(file, 'r'); +if fid < 0 + error('GECKO:TomlAdapter', 'Cannot read the spontaneous reactions file %s', file); +end +header = fgetl(fid); +nCols = numel(strsplit(header, '\t')); +if nCols >= 2 + cols = textscan(fid, ['%q %q' repmat(' %*q', 1, nCols-2)], 'Delimiter', '\t'); + keep = ismember(lower(strtrim(cols{2})), {'1','true'}); + rxns = cols{1}(keep); +else + cols = textscan(fid, '%q', 'Delimiter', '\t'); + rxns = cols{1}; +end +fclose(fid); +end diff --git a/src/model_adapter/adapterParameters.tsv b/src/model_adapter/adapterParameters.tsv new file mode 100644 index 00000000..b0c11440 --- /dev/null +++ b/src/model_adapter/adapterParameters.tsv @@ -0,0 +1,42 @@ +toml_key matlab_field default description +project_format projectFormat Layout version of the project folder; upgradeGECKOproject and geckopy upgrade write 4 +conv_gem convGEM Path to the conventional GEM, relative to the project folder +org_name org_name Scientific name of the organism +sigma sigma 0.5 Average enzyme saturation factor +p_tot Ptot 0.5 Total protein content [g protein/gDW] +f f 0.5 Fraction of enzymes in the model [g enzyme/g protein] +gr_exp gR_exp 0.41 Growth rate the model should reach when not limited by nutrient uptake [1/h] +c_source c_source "" Exchange reaction of the main carbon source +bio_rxn bioRxn "" Biomass pseudoreaction +enzyme_comp enzyme_comp "cytoplasm" Compartment of the protein pseudometabolites +kcat_aggregate_brenda kcatAggregation "max" BRENDA aggregate read by fuzzyKcatMatching: max or median +kcat_aggregate_candidates "max" Aggregation of several candidate kcats for one reaction (geckopy) +kcat_aggregate_isozymes "mean" Aggregation of isozyme kcats when filling a missing value (geckopy) +kegg.id kegg.ID "sce" KEGG organism code +kegg.gene_id kegg.geneID "kegg" Field in the KEGG entry that matches model gene identifiers +uniprot.type uniprot.type "taxonomy" Whether uniprot.id is a taxonomy or a proteome identifier +uniprot.id uniprot.ID "559292" Taxonomy or proteome identifier +uniprot.gene_id_field uniprot.geneIDfield "gene_oln" UniProt field that matches model gene identifiers +uniprot.reviewed uniprot.reviewed false Use only reviewed (Swiss-Prot) entries +complex.taxonomic_id complex.taxonomicID Taxonomy identifier for Complex Portal +spontaneous.name_contains spontaneous.name_contains Reactions whose name contains this text are spontaneous +spontaneous.file spontaneous.file TSV of spontaneous reactions, relative to the project folder: reaction identifiers, optionally a 0/1 column +evotune.sigma0_log_default evotune.sigma0logDefault 0.5 Prior standard deviation (log) for kcats whose source is in no group +evotune.source_groups evotune.kcatSources Trust tiers: group name to the ec.source values it covers +evotune.sigma0_log_source evotune.sigma0logSource Prior standard deviation (log) per group +evotune.rmse_threshold evotune.rmseThreshold 0.2 Stop when the best RMSE reaches this +evotune.max_generations evotune.maxGenerations 150 Maximum number of CMA-ES generations +evotune.max_growth_weight evotune.maxGrowthWeight 1.0 Weight of the maximum-growth RMSE against the flux RMSE +evotune.prior_penalty_weight evotune.priorPenaltyWeight 0.03 Weight of the prior term in the search objective +evotune.tie_isozymes evotune.tieIsozymes true Give isozyme copies of one reaction a single kcat +okp.method okp.method "CataPro" OpenKineticsPredictor method +okp.handle_long_sequences okp.handleLongSequences "truncate" How OpenKineticsPredictor handles sequences that are too long +okp.include_similarity_columns okp.includeSimilarityColumns true Return similarity to the method's training data +okp.canonicalize_substrates okp.canonicalizeSubstrates true Canonicalize substrate SMILES before prediction +kcat_assignment.preset Kcat assignment preset: brenda_ec_tree (used when neither preset nor stages are given), ec_tree_homologs, ec_tree_okp, okp, gecko_median or gecko_classic +kcat_assignment.isozymes true Fill reactions without a kcat from their isozymes after the stages +kcat_assignment.standard true Give the remaining reactions the standard kcat +kcat_assignment.stage Stages instead of a preset: action (select or combine), sources, criteria and BRENDA limits ([[kcat_assignment.stage]]) +kcat_sources Settings per kcat source file, e.g. [kcat_sources.brenda] aggregation; [kcat_sources.okp] methods lists the OKP methods of the okp source group +matlab.make_model_anaerobic matlab.makeModelAnaerobic MATLAB function that constrains the ecModel to anaerobic growth +matlab.change_protein_biomass matlab.changeProteinBiomass MATLAB function that changes the protein content of the biomass diff --git a/src/model_adapter/adapterTemplate.m b/src/model_adapter/adapterTemplate.m index 3d0c8c3b..28cc98dd 100644 --- a/src/model_adapter/adapterTemplate.m +++ b/src/model_adapter/adapterTemplate.m @@ -43,6 +43,13 @@ % Provide your organism scientific name obj.params.org_name = 'genus species'; + + % Which BRENDA aggregate fuzzyKcatMatching reads for each + % (EC, substrate, organism) triple: 'max' (the highest + % turnover reported) or 'median' (the middle one). Can also + % be given per call as + % fuzzyKcatMatching(model,'kcatAggregation','median'). + obj.params.kcatAggregation = 'max'; % Taxonomic identifier for Complex Portal obj.params.complex.taxonomicID = []; diff --git a/src/model_adapter/adapterTemplate.toml b/src/model_adapter/adapterTemplate.toml new file mode 100644 index 00000000..7c4bae8c --- /dev/null +++ b/src/model_adapter/adapterTemplate.toml @@ -0,0 +1,137 @@ +# Model adapter for KEY_NAME. +# Read by GECKO (ModelAdapterManager.setDefault on the project folder) and +# by geckopy (ModelAdapter.from_folder). Paths are relative to the project +# folder. Keys that are left out get the default listed, with their MATLAB +# names, in GECKO's src/model_adapter/adapterParameters.tsv. + +# Conventional GEM that this ecModel is built from. +conv_gem = "models/yourModel.xml" + +# Scientific name of the organism. +org_name = "genus species" + +# Average enzyme saturation factor. +sigma = 0.5 +# Total protein content in the cell [g protein/gDW]. +p_tot = 0.5 +# Fraction of enzymes in the model [g enzyme/g protein]. +f = 0.5 +# Growth rate the model should reach when not limited by nutrient uptake, +# for example the maximum growth rate [1/h]. +gr_exp = 0.41 + +# Exchange reaction of glucose, or another preferred carbon source. +c_source = "r_1714" +# Biomass pseudoreaction. +bio_rxn = "r_4041" +# Compartment of the protein pseudometabolites. They can all sit in one +# compartment, whichever compartments the enzymes act in; typically the +# cytoplasm. +enzyme_comp = "cytoplasm" + +# Which BRENDA aggregate fuzzyKcatMatching reads for each (EC, substrate, +# organism): "max" (the highest turnover reported) or "median". +kcat_aggregate_brenda = "max" + +[kegg] +# KEGG organism code, from https://www.genome.jp/kegg/catalog/org_list.html +id = "sce" +# Field for the KEGG gene identifier; it should match the gene identifiers +# of the model. "kegg" takes the KEGG entry identifier (for example +# YER023W: https://www.genome.jp/dbget-bin/www_bget?sce:YER023W). Gene +# identifiers from the "Other DBs" section of the KEGG page can also be +# used, for example "NCBI-GeneID", "UniProt" or "Ensembl"; not all are +# available for every organism and gene. +gene_id = "kegg" + +[uniprot] +# "proteome" (https://www.uniprot.org/proteomes/) or "taxonomy" +# (https://www.uniprot.org/taxonomy), and the matching identifier. +type = "taxonomy" +id = "559292" +# UniProt field that matches the gene identifiers of the model: one of the +# "Returned Field" entries under "Names & Taxonomy" at +# https://www.uniprot.org/help/return_fields +gene_id_field = "gene_oln" +# Use only reviewed (Swiss-Prot) entries. They have the highest confidence, +# but coverage can be (very) low for non-model organisms. +reviewed = false + +[complex] +# Taxonomy identifier for Complex Portal; leave out to skip it. +# taxonomic_id = 559292 + +# Reactions without an enzyme: those whose name contains name_contains, +# and those listed in file (a TSV with a header row, reaction identifiers +# in the first column and optionally a 0/1 column). +[spontaneous] +name_contains = "spontaneous" +# file = "data/spontaneousReactions.tsv" + +# Hyperparameters for evotune (CMA-ES) kcat tuning. +[evotune] +# Prior standard deviation (log) for kcats whose source is in no group. +sigma0_log_default = 0.5 +# Weight on the max-growth RMSE against the flux RMSE: +# (rmse_flux + w * rmse_max_growth) / (w + 1). At 1 both count equally. +max_growth_weight = 1.0 +# Weight on a prior term in the search objective, +# rmse + w * mean((log(k/k0) / sigma0_log)^2). Keeps large corrections +# reproducible across seeds; 0 scores on RMSE alone. +prior_penalty_weight = 0.03 +# Give isozyme copies of one reaction (sharing a prior value and a source) +# a single shared kcat, so the search cannot invent a distinction the kcat +# assignment never made. +tie_isozymes = true +# Stop when the RMSE falls below this. +rmse_threshold = 0.2 +# Maximum number of CMA-ES generations. +max_generations = 150 + +# Kcat sources, from least to most trusted, each with its prior width +# (lower is more trusted). +[evotune.source_groups.dlkcat] +sources = ["dlkcat"] + +[evotune.source_groups.brenda] +sources = ["brenda"] + +[evotune.source_groups.custom] +sources = ["custom"] + +[evotune.sigma0_log_source] +dlkcat = 0.4 +brenda = 0.2 +custom = 0.1 + +# How kcats are assigned from the kcat source files in data/kcats (see +# collectKcats and assignKcats): a preset, or [[kcat_assignment.stage]] +# tables instead. +# - brenda_ec_tree: custom kcats, the BRENDA median of measurements of the +# organism on the reaction's substrate, the EC tree (the EC's median kcat, +# leaning on its EC class when it has few measurements); then the +# OpenKineticsPredictor (OKP) methods combined for reactions without an +# EC number. +# - ec_tree_okp: custom kcats, the organism's own BRENDA value, then the EC +# tree and the OKP methods combined. +# - okp: custom kcats, then the OKP methods combined. +# - gecko_median and gecko_classic: BRENDA's fuzzy matches and DLKcat, with +# the BRENDA median and maximum. +[kcat_assignment] +preset = "brenda_ec_tree" +isozymes = true +standard = true + +# Settings per kcat source, used by updateKcatSources, for example the OKP +# methods the presets combine (default: all methods with combination +# parameters): +# [kcat_sources.okp] +# methods = ["CataPro", "KinForm-H", "UniKP"] + +# Read by GECKO only. Names of MATLAB functions, for instance in the code +# folder, used during kcat tuning: one that constrains the ecModel to +# anaerobic growth, and one that changes the protein content of the +# biomass (it receives the ecModel and the protein content). +[matlab] +# make_model_anaerobic = "anaerobicModel" +# change_protein_biomass = "scaleBiomassProtein" diff --git a/src/model_adapter/convertAdapterToToml.m b/src/model_adapter/convertAdapterToToml.m new file mode 100644 index 00000000..fe24c636 --- /dev/null +++ b/src/model_adapter/convertAdapterToToml.m @@ -0,0 +1,228 @@ +function report = convertAdapterToToml(adapter, tomlFile) +% convertAdapterToToml Write the parameters of an adapter class to model_adapter.toml. +% +% Converts an existing ModelAdapter class (GECKO 3 or 4 style) to +% model_adapter.toml, the configuration file shared by GECKO and geckopy. +% Parameter names are translated with adapterParameters.tsv (for instance +% Ptot becomes p_tot), paths inside the project folder are written +% relative to it, and parameters without a geckopy name are kept under +% [matlab.params], so that loadAdapterParams gives back the same params. +% +% Methods that the adapter class overrides cannot be written to TOML. +% They are listed in the report, with how to carry them over: +% - getSpontaneousReactions: set [spontaneous] name_contains or file; +% - makeModelAnaerobic, changeProteinBiomass: set [matlab] +% make_model_anaerobic or change_protein_biomass to a function name; +% - other methods: keep the adapter class and let its constructor call +% loadAdapterParams. +% +% Parameters +% ---------- +% adapter : ModelAdapter or char +% an adapter object, or the path to its .m file. +% tomlFile : char, optional +% file to write (default: model_adapter.toml in the adapter's +% params.path). An existing file is not overwritten. +% +% Returns +% ------- +% report : struct +% - file: the file written; +% - unmapped: parameters written under [matlab.params]; +% - methods: overridden methods that need carrying over by hand. +% +% Examples +% -------- +% report = convertAdapterToToml(fullfile(projectPath,'MyGEMAdapter.m')); +% adapter = TomlAdapter(projectPath); +% +% See also +% -------- +% TomlAdapter, loadAdapterParams, writeAdapterToml + +if ischar(adapter) || isstring(adapter) + adapter = ModelAdapterManager.getAdapter(char(adapter)); +end +params = adapter.params; +if isfield(params,'path') && isstruct(params.path) + params.path = params.path.Name; % a struct path, as some old adapters keep it +end +projectPath = ''; +if isfield(params,'path') + projectPath = char(params.path); +end +if nargin < 2 || isempty(tomlFile) + tomlFile = fullfile(projectPath, 'model_adapter.toml'); +end +if isfile(tomlFile) + error('GECKO:convertAdapterToToml', '%s exists already; it is not overwritten.', tomlFile); +end + +map = readMap(); +data = struct(); +used = {}; +for k = 1:numel(map.tomlKey) + field = map.matlabField{k}; + if isempty(field) || any(strcmp(field, {'evotune.kcatSources','evotune.sigma0logSource'})) + continue + end + [found, value] = getDotted(params, field); + if ~found || (isempty(value) && ~ischar(value)) + if found + used{end+1} = field; %#ok + end + continue + end + used{end+1} = field; %#ok + if any(strcmp(map.tomlKey{k}, {'conv_gem','spontaneous.file'})) + value = relativePath(char(value), projectPath); + end + data = setDotted(data, map.tomlKey{k}, value); +end +used{end+1} = 'path'; + +% Trust tiers: one group per ec.source value. +if isfield(params,'evotune') && isfield(params.evotune,'kcatSources') + used = [used, {'evotune.kcatSources','evotune.sigma0logSource'}]; + sources = params.evotune.kcatSources; + widths = params.evotune.sigma0logSource; + groups = struct(); + sigma0 = struct(); + for k = 1:numel(sources) + name = matlab.lang.makeValidName(sources{k}); + groups.(name).sources = sources(k); + sigma0.(name) = widths(k); + end + data.evotune.source_groups = groups; + data.evotune.sigma0_log_source = sigma0; +end + +% Everything else is kept for GECKO under [matlab.params]. +extra = unusedFields(params, '', used); +report.unmapped = {}; +if ~isempty(fieldnames(extra)) + data.matlab.params = extra; + report.unmapped = flattenNames(extra, ''); +end + +report.methods = overriddenMethods(adapter); +report.file = tomlFile; + +header = {sprintf('Model adapter for %s, converted from %s.', ... + getOr(params,'org_name','this project'), class(adapter)), ... + 'Shared by GECKO (MATLAB) and geckopy; see adapterParameters.tsv in GECKO for every key.'}; +writeAdapterToml(data, tomlFile, header); + +fprintf('Wrote %s.\n', tomlFile); +if ~isempty(report.unmapped) + fprintf('Kept for GECKO only, under [matlab.params]: %s\n', strjoin(report.unmapped, ', ')); +end +if ~isempty(report.methods) + printOrange(sprintf(['%s overrides methods that a TOML file cannot hold: %s.\n' ... + 'Set [spontaneous] for getSpontaneousReactions, [matlab] function names for\n' ... + 'makeModelAnaerobic and changeProteinBiomass, or keep the class and let its\n' ... + 'constructor call loadAdapterParams.\n'], class(adapter), strjoin(report.methods, ', '))); +end +end + +function map = readMap() +file = fullfile(fileparts(mfilename('fullpath')), 'adapterParameters.tsv'); +fid = fopen(file, 'r'); +cols = textscan(fid, '%s %s %s %s', 'Delimiter', '\t', 'HeaderLines', 1, 'Whitespace', ''); +fclose(fid); +map.tomlKey = cols{1}; +map.matlabField = cols{2}; +end + +function names = overriddenMethods(adapter) +% Methods defined by the adapter class itself rather than ModelAdapter. +names = {}; +mc = metaclass(adapter); +for k = 1:numel(mc.MethodList) + m = mc.MethodList(k); + if strcmp(m.DefiningClass.Name, mc.Name) && ~strcmp(m.Name, mc.Name) && ~m.Static + names{end+1} = m.Name; %#ok + end +end +names = sort(names); +end + +function extra = unusedFields(s, prefix, used) +extra = struct(); +fields = fieldnames(s); +for k = 1:numel(fields) + name = fields{k}; + if ~isempty(prefix) + name = [prefix '.' name]; + end + if any(strcmp(name, used)) + continue + end + value = s.(fields{k}); + if isstruct(value) && isscalar(value) && any(startsWith(used, [name '.'])) + sub = unusedFields(value, name, used); + if ~isempty(fieldnames(sub)) + extra.(fields{k}) = sub; + end + elseif ~(isempty(value) && ~ischar(value) && ~iscell(value)) + extra.(fields{k}) = value; + end +end +end + +function names = flattenNames(s, prefix) +names = {}; +fields = fieldnames(s); +for k = 1:numel(fields) + name = fields{k}; + if ~isempty(prefix) + name = [prefix '.' name]; + end + if isstruct(s.(fields{k})) + names = [names, flattenNames(s.(fields{k}), name)]; %#ok + else + names{end+1} = name; %#ok + end +end +end + +function p = relativePath(p, projectPath) +p = strrep(p, '\', '/'); +base = strrep(projectPath, '\', '/'); +if ~isempty(base) && startsWith(p, [base '/']) + p = p(numel(base)+2:end); +end +end + +function [found, value] = getDotted(s, key) +parts = strsplit(key, '.'); +value = s; +found = true; +for k = 1:numel(parts) + if ~isstruct(value) || ~isfield(value, parts{k}) + found = false; + value = []; + return + end + value = value.(parts{k}); +end +end + +function s = setDotted(s, key, value) +parts = strsplit(key, '.'); +if numel(parts) == 1 + s.(parts{1}) = value; + return +end +if ~isfield(s, parts{1}) || ~isstruct(s.(parts{1})) + s.(parts{1}) = struct(); +end +s.(parts{1}) = setDotted(s.(parts{1}), strjoin(parts(2:end), '.'), value); +end + +function v = getOr(s, field, default) +v = default; +if isfield(s, field) && ~isempty(s.(field)) + v = s.(field); +end +end diff --git a/src/model_adapter/loadAdapterParams.m b/src/model_adapter/loadAdapterParams.m new file mode 100644 index 00000000..94cd4bbd --- /dev/null +++ b/src/model_adapter/loadAdapterParams.m @@ -0,0 +1,249 @@ +function params = loadAdapterParams(tomlFile) +% loadAdapterParams Read model adapter parameters from a TOML file. +% +% Reads model_adapter.toml, the configuration file shared by GECKO and +% geckopy, and returns the parameters with GECKO's field names, so that +% they can be used as ModelAdapter.params. Keys are translated with +% adapterParameters.tsv (for instance p_tot becomes Ptot); keys that are +% not given get the default listed there, which is geckopy's default. +% +% Parameters +% ---------- +% tomlFile : char +% path to model_adapter.toml, or to the project folder that holds it. +% +% Returns +% ------- +% params : struct +% the adapter parameters, as in ModelAdapter.params: +% - path: the project folder (the folder of the TOML file); +% - convGEM and spontaneous.file: absolute paths; +% - evotune.kcatSources and evotune.sigma0logSource: built from the +% evotune.source_groups and evotune.sigma0_log_source tables, one +% entry per ec.source value; +% - fields under [matlab.params] are copied as they are, for +% parameters that only GECKO uses. +% +% Examples +% -------- +% params = loadAdapterParams(fullfile(projectPath,'model_adapter.toml')); +% +% See also +% -------- +% TomlAdapter, readAdapterToml, convertAdapterToToml + +if isfolder(tomlFile) + tomlFile = fullfile(tomlFile, 'model_adapter.toml'); +end +if ~isfile(tomlFile) + error('GECKO:loadAdapterParams', 'No model adapter file found at %s', tomlFile); +end +tomlFile = char(tomlFile); +[projectPath, ~, ~] = fileparts(getAbsolutePath(tomlFile)); + +data = readAdapterToml(tomlFile); +map = adapterParameterMap(); + +% Unknown keys are errors, as in geckopy, so that a typo is not ignored. +known = [map.tomlKey; {'evotune.source_groups'; 'evotune.sigma0_log_source'}]; +checkKnownKeys(data, '', known, tomlFile); + +params = struct(); +params.path = projectPath; +for k = 1:numel(map.tomlKey) + key = map.tomlKey{k}; + if any(strcmp(key, {'evotune.source_groups', 'evotune.sigma0_log_source'})) + continue + end + [found, value] = getDotted(data, key); + if ~found + if isempty(map.default{k}) + continue + end + value = map.default{k}; + end + if isempty(map.matlabField{k}) + field = key; % a key that only geckopy reads keeps its name + else + field = map.matlabField{k}; + end + params = setDotted(params, field, value); +end + +if ~isfield(params, 'complex') + params.complex.taxonomicID = []; % geckopy's default: no Complex Portal query +end + +for f = {'convGEM'} + if isfield(params, f{1}) + params.(f{1}) = projectFile(projectPath, params.(f{1})); + end +end +if isfield(params, 'spontaneous') && isfield(params.spontaneous, 'file') + params.spontaneous.file = projectFile(projectPath, params.spontaneous.file); +end + +params = sourceGroups(params, data, tomlFile); + +if isfield(data, 'matlab') && isfield(data.matlab, 'params') + params = mergeStruct(params, data.matlab.params); +end +end + +function map = adapterParameterMap() +% Reads adapterParameters.tsv into toml keys, MATLAB fields and defaults. +file = fullfile(fileparts(mfilename('fullpath')), 'adapterParameters.tsv'); +fid = fopen(file, 'r'); +cols = textscan(fid, '%s %s %s %s', 'Delimiter', '\t', 'HeaderLines', 1, ... + 'Whitespace', '', 'ReturnOnError', false); +fclose(fid); +map.tomlKey = cols{1}; +map.matlabField = cols{2}; +map.default = cell(size(cols{3})); +for k = 1:numel(cols{3}) + if ~isempty(cols{3}{k}) + map.default{k} = parseDefault(cols{3}{k}); + end +end +end + +function value = parseDefault(text) +% A default is written as a TOML value. +tmp = [tempname '.toml']; +fid = fopen(tmp, 'w'); +fprintf(fid, 'x = %s\n', text); +fclose(fid); +cleanup = onCleanup(@() delete(tmp)); +data = readAdapterToml(tmp); +value = data.x; +if ischar(value) && isempty(value) + value = ''; +end +end + +function checkKnownKeys(s, prefix, known, tomlFile) +fields = fieldnames(s); +for k = 1:numel(fields) + key = fields{k}; + if ~isempty(prefix) + key = [prefix '.' key]; + end + if strcmp(key, 'matlab.params') + continue % free-form parameters for GECKO only + end + if any(strcmp(key, known)) || any(startsWith(known, [key '.'])) + if isstruct(s.(fields{k})) && ~any(strcmp(key, known)) + checkKnownKeys(s.(fields{k}), key, known, tomlFile); + end + continue + end + if any(startsWith(key, {'evotune.source_groups.', 'evotune.sigma0_log_source.'})) + continue + end + error('GECKO:loadAdapterParams', ['Unknown key "%s" in %s. Parameters that only ' ... + 'GECKO uses go under [matlab.params].'], key, tomlFile); +end +end + +function params = sourceGroups(params, data, tomlFile) +% evotune.source_groups and evotune.sigma0_log_source become the +% kcatSources and sigma0logSource lists that evotune reads: one entry per +% ec.source value, with its group's prior width. +groups = struct(); +widths = struct(); +if isfield(data, 'evotune') && isfield(data.evotune, 'source_groups') + groups = data.evotune.source_groups; + if isfield(data.evotune, 'sigma0_log_source') + widths = data.evotune.sigma0_log_source; + end +else + % geckopy's defaults (EvotuneParams.source_groups, sigma0_log_source). + groups.dlkcat.sources = {'dlkcat'}; + groups.brenda.sources = {'brenda'}; + groups.custom.sources = {'custom'}; + widths.dlkcat = 0.4; + widths.brenda = 0.2; + widths.custom = 0.1; +end +names = fieldnames(groups); +if ~isempty(setxor(names, fieldnames(widths))) + error('GECKO:loadAdapterParams', ['%s: evotune.sigma0_log_source must have ' ... + 'the same group names as evotune.source_groups'], tomlFile); +end +kcatSources = {}; +sigma0logSource = []; +for k = 1:numel(names) + group = groups.(names{k}); + sources = {}; + if isfield(group, 'sources') + sources = group.sources; + if ischar(sources) + sources = {sources}; + end + end + if isfield(group, 'match_okp') && group.match_okp && isfield(params, 'okp') + sources{end+1} = params.okp.method; %#ok + end + kcatSources = [kcatSources, sources]; %#ok + sigma0logSource = [sigma0logSource; repmat(widths.(names{k}), numel(sources), 1)]; %#ok +end +params.evotune.kcatSources = kcatSources; +params.evotune.sigma0logSource = sigma0logSource; +end + +function [found, value] = getDotted(s, key) +parts = strsplit(key, '.'); +value = s; +found = true; +for k = 1:numel(parts) + if ~isstruct(value) || ~isfield(value, parts{k}) + found = false; + value = []; + return + end + value = value.(parts{k}); +end +end + +function s = setDotted(s, key, value) +parts = strsplit(key, '.'); +if numel(parts) == 1 + s.(parts{1}) = value; + return +end +if ~isfield(s, parts{1}) || ~isstruct(s.(parts{1})) + s.(parts{1}) = struct(); +end +s.(parts{1}) = setDotted(s.(parts{1}), strjoin(parts(2:end), '.'), value); +end + +function s = mergeStruct(s, extra) +fields = fieldnames(extra); +for k = 1:numel(fields) + value = extra.(fields{k}); + if isstruct(value) && isscalar(value) && isfield(s, fields{k}) && isstruct(s.(fields{k})) + s.(fields{k}) = mergeStruct(s.(fields{k}), value); + else + s.(fields{k}) = value; + end +end +end + +function p = projectFile(projectPath, p) +if isempty(p) + return +end +if ~isAbsolute(p) + p = fullfile(projectPath, p); +end +end + +function tf = isAbsolute(p) +tf = startsWith(p, '/') || startsWith(p, '\') || ~isempty(regexp(p, '^[A-Za-z]:', 'once')); +end + +function p = getAbsolutePath(p) +if ~isAbsolute(p) + p = fullfile(pwd, p); +end +end diff --git a/src/model_adapter/readAdapterToml.m b/src/model_adapter/readAdapterToml.m new file mode 100644 index 00000000..eca857f2 --- /dev/null +++ b/src/model_adapter/readAdapterToml.m @@ -0,0 +1,471 @@ +function data = readAdapterToml(filename) +% readAdapterToml Read a model adapter TOML file into a struct. +% +% Reads the subset of TOML that model adapter files use: comments, bare +% keys, basic and literal strings, integers, floats, booleans, arrays of +% these values (also over several lines), tables ([kegg], [a.b.c]) and +% arrays of tables ([[a]]). Anything else, such as dates, inline tables, +% multi-line strings or quoted keys, stops with an error that names the +% line. +% +% Parameters +% ---------- +% filename : char +% path to the TOML file. +% +% Returns +% ------- +% data : struct +% one field per key, with tables as nested structs and arrays of +% tables as struct arrays. Strings are char, numbers double, booleans +% logical, arrays of strings a 1xn cell and arrays of numbers or +% booleans a 1xn vector. An empty array is an empty cell. +% +% Examples +% -------- +% data = readAdapterToml(fullfile(projectPath,'model_adapter.toml')); +% +% See also +% -------- +% writeAdapterToml, loadAdapterParams + +text = fileread(filename); +text = strrep(text, sprintf('\r\n'), newline); +lines = strsplit(text, newline, 'CollapseDelimiters', false); + +data = struct(); +tablePath = {}; % keys of the current table, each element {name, arrayIndex} +arrayNames = {}; % dotted names declared as arrays of tables +i = 0; +while i < numel(lines) + i = i + 1; + lineNo = i; + line = stripComment(lines{i}, filename, lineNo); + if isempty(strtrim(line)) + continue + end + trimmed = strtrim(line); + if startsWith(trimmed, '[[') + if ~endsWith(trimmed, ']]') + tomlError(filename, lineNo, 'array of tables header must end with ]]'); + end + keys = splitKey(trimmed(3:end-2), filename, lineNo); + [data, tablePath] = appendTableArray(data, keys, arrayNames, filename, lineNo); + arrayNames = union(arrayNames, {strjoin(keys, '.')}); + elseif startsWith(trimmed, '[') + if ~endsWith(trimmed, ']') + tomlError(filename, lineNo, 'table header must end with ]'); + end + keys = splitKey(trimmed(2:end-1), filename, lineNo); + tablePath = resolvePath(data, keys, arrayNames); + data = ensureTable(data, tablePath, filename, lineNo); + else + eq = findUnquoted(line, '='); + if isempty(eq) + tomlError(filename, lineNo, 'expected key = value'); + end + keys = splitKey(line(1:eq-1), filename, lineNo); + valueText = strtrim(line(eq+1:end)); + % Arrays may span several lines: read on until the brackets close. + while startsWith(valueText, '[') && bracketDepth(valueText) > 0 + if i >= numel(lines) + tomlError(filename, lineNo, 'array is not closed'); + end + i = i + 1; + valueText = [valueText ' ' strtrim(stripComment(lines{i}, filename, i))]; %#ok + end + value = parseValue(valueText, filename, lineNo); + data = setKey(data, [tablePath, keyPath(keys)], value, filename, lineNo); + end +end +end + +function line = stripComment(line, filename, lineNo) +% Removes a # comment that is not inside a string. +inBasic = false; inLiteral = false; k = 1; +while k <= numel(line) + c = line(k); + if inBasic + if c == '\' + k = k + 1; + elseif c == '"' + inBasic = false; + end + elseif inLiteral + if c == '''' + inLiteral = false; + end + elseif c == '"' + if k + 2 <= numel(line) && strcmp(line(k:k+2), '"""') + tomlError(filename, lineNo, 'multi-line strings are not supported'); + end + inBasic = true; + elseif c == '''' + if k + 2 <= numel(line) && strcmp(line(k:k+2), '''''''') + tomlError(filename, lineNo, 'multi-line strings are not supported'); + end + inLiteral = true; + elseif c == '#' + line = line(1:k-1); + return + end + k = k + 1; +end +end + +function idx = findUnquoted(line, ch) +% Position of the first ch outside a string, or empty. +idx = []; +inBasic = false; inLiteral = false; k = 1; +while k <= numel(line) + c = line(k); + if inBasic + if c == '\' + k = k + 1; + elseif c == '"' + inBasic = false; + end + elseif inLiteral + if c == '''' + inLiteral = false; + end + elseif c == '"' + inBasic = true; + elseif c == '''' + inLiteral = true; + elseif c == ch + idx = k; + return + end + k = k + 1; +end +end + +function depth = bracketDepth(text) +% Open [ minus closed ] outside strings. +depth = 0; inBasic = false; inLiteral = false; k = 1; +while k <= numel(text) + c = text(k); + if inBasic + if c == '\' + k = k + 1; + elseif c == '"' + inBasic = false; + end + elseif inLiteral + if c == '''' + inLiteral = false; + end + elseif c == '"' + inBasic = true; + elseif c == '''' + inLiteral = true; + elseif c == '[' + depth = depth + 1; + elseif c == ']' + depth = depth - 1; + end + k = k + 1; +end +end + +function keys = splitKey(text, filename, lineNo) +% Dotted bare key into its parts. +keys = strtrim(strsplit(strtrim(text), '.')); +for k = 1:numel(keys) + if isempty(regexp(keys{k}, '^[A-Za-z][A-Za-z0-9_]*$', 'once')) + tomlError(filename, lineNo, sprintf(['key "%s" is not supported: use letters, ' ... + 'digits and underscores, starting with a letter'], keys{k})); + end +end +end + +function p = keyPath(keys) +p = cellfun(@(k) {k, 0}, keys, 'UniformOutput', false); +end + +function path = resolvePath(data, keys, arrayNames) +% Path of {name, index} pairs; a key that names an array of tables refers +% to its last element. +path = cell(1, numel(keys)); +for k = 1:numel(keys) + idx = 0; + if ismember(strjoin(keys(1:k), '.'), arrayNames) + idx = numel(getKey(data, [path(1:k-1), {{keys{k}, 0}}])); + end + path{k} = {keys{k}, idx}; +end +end + +function [data, tablePath] = appendTableArray(data, keys, arrayNames, filename, lineNo) +% Appends a new element to the array of tables named by keys. +parent = resolvePath(data, keys(1:end-1), arrayNames); +data = ensureTable(data, parent, filename, lineNo); +name = strjoin(keys, '.'); +existing = getKey(data, [parent, {{keys{end}, 0}}]); +if isempty(existing) || ~ismember(name, arrayNames) + if ~isempty(existing) + tomlError(filename, lineNo, sprintf('"%s" is already a table or value', name)); + end + n = 1; +else + n = numel(existing) + 1; +end +tablePath = [parent, {{keys{end}, n}}]; +data = setTableElement(data, parent, keys{end}, n); +end + +function data = ensureTable(data, path, filename, lineNo) +if isempty(path) + return +end +name = path{1}{1}; idx = path{1}{2}; +if ~isfield(data, name) + data.(name) = struct(); +elseif ~isstruct(data.(name)) + tomlError(filename, lineNo, sprintf('"%s" is already a value, not a table', name)); +end +child = data.(name); +if idx == 0 + child = ensureTable(child, path(2:end), filename, lineNo); + data.(name) = child; +else + element = child(idx); + element = ensureTable(element, path(2:end), filename, lineNo); + data.(name) = assignElement(child, idx, element); +end +end + +function data = setTableElement(data, parent, name, n) +% Adds element n (an empty struct) to the table array name under parent. +if isempty(parent) + if ~isfield(data, name) || isempty(data.(name)) || n == 1 + data.(name) = struct(); + else + data.(name) = assignElement(data.(name), n, struct()); + end + return +end +pname = parent{1}{1}; pidx = parent{1}{2}; +child = data.(pname); +if pidx == 0 + data.(pname) = setTableElement(child, parent(2:end), name, n); +else + element = setTableElement(child(pidx), parent(2:end), name, n); + data.(pname) = assignElement(child, pidx, element); +end +end + +function value = getKey(data, path) +value = []; +node = data; +for k = 1:numel(path) + name = path{k}{1}; idx = path{k}{2}; + if ~isstruct(node) || ~isfield(node, name) + value = []; + return + end + node = node.(name); + if idx > 0 + node = node(idx); + end +end +value = node; +end + +function data = setKey(data, path, value, filename, lineNo) +name = path{1}{1}; idx = path{1}{2}; +if numel(path) == 1 + % [] only fills a field that another element of a table array has; + % TOML itself has no empty value. + if isfield(data, name) && ~isequal(data.(name), []) + tomlError(filename, lineNo, sprintf('key "%s" is defined twice', name)); + end + data.(name) = value; + return +end +if ~isfield(data, name) + data.(name) = struct(); +elseif ~isstruct(data.(name)) + tomlError(filename, lineNo, sprintf('"%s" is already a value, not a table', name)); +end +child = data.(name); +if idx == 0 + data.(name) = setKey(child, path(2:end), value, filename, lineNo); +else + element = setKey(child(idx), path(2:end), value, filename, lineNo); + data.(name) = assignElement(child, idx, element); +end +end + +function s = assignElement(s, idx, element) +% Assigns element to s(idx), adding fields so the struct array stays +% consistent. +if idx > numel(s) || isempty(fieldnames(s)) + if numel(s) == 1 && isempty(fieldnames(s)) && idx == 1 + s = element; + return + end +end +fs = fieldnames(element); +for f = 1:numel(fs) + if ~isfield(s, fs{f}) + [s.(fs{f})] = deal([]); + end +end +fs = fieldnames(s); +for f = 1:numel(fs) + if ~isfield(element, fs{f}) + element.(fs{f}) = []; + end +end +element = orderfields(element, s(1)); +s(idx) = element; +end + +function value = parseValue(text, filename, lineNo) +text = strtrim(text); +if isempty(text) + tomlError(filename, lineNo, 'missing value'); +end +switch text(1) + case '"' + [value, rest] = parseBasicString(text, filename, lineNo); + case '''' + close = find(text(2:end) == '''', 1) + 1; + if isempty(close) + tomlError(filename, lineNo, 'string is not closed'); + end + value = text(2:close-1); + rest = text(close+1:end); + case '[' + [value, rest] = parseArray(text, filename, lineNo); + case '{' + tomlError(filename, lineNo, 'inline tables are not supported; use a [table] instead'); + otherwise + [value, rest] = parseScalar(text, filename, lineNo); +end +if ~isempty(strtrim(rest)) + tomlError(filename, lineNo, sprintf('unexpected text after the value: %s', strtrim(rest))); +end +end + +function [value, rest] = parseBasicString(text, filename, lineNo) +value = ''; +k = 2; +while k <= numel(text) + c = text(k); + if c == '"' + rest = text(k+1:end); + return + elseif c == '\' + if k == numel(text) + break + end + e = text(k+1); + switch e + case 'n', value(end+1) = newline; + case 't', value(end+1) = sprintf('\t'); + case '"', value(end+1) = '"'; + case '\', value(end+1) = '\'; + case 'u' + value(end+1) = char(hex2dec(text(k+2:k+5))); + k = k + 4; + otherwise + tomlError(filename, lineNo, sprintf('escape \\%s is not supported', e)); + end + k = k + 2; + continue + else + value(end+1) = c; %#ok + end + k = k + 1; +end +tomlError(filename, lineNo, 'string is not closed'); +end + +function [value, rest] = parseArray(text, filename, lineNo) +% Parses [a, b, ...]; returns a cell for strings, a vector otherwise. +items = {}; +k = 2; +while true + while k <= numel(text) && (isspace(text(k)) || text(k) == ',') + k = k + 1; + end + if k > numel(text) + tomlError(filename, lineNo, 'array is not closed'); + end + if text(k) == ']' + rest = text(k+1:end); + break + end + if text(k) == '[' + tomlError(filename, lineNo, 'nested arrays are not supported'); + end + % Find the end of this element. + if text(k) == '"' + [item, after] = parseBasicString(text(k:end), filename, lineNo); + k = numel(text) - numel(after) + 1; + elseif text(k) == '''' + close = find(text(k+1:end) == '''', 1) + k; + if isempty(close) + tomlError(filename, lineNo, 'string is not closed'); + end + item = text(k+1:close-1); + k = close + 1; + else + stop = k; + while stop <= numel(text) && text(stop) ~= ',' && text(stop) ~= ']' + stop = stop + 1; + end + [item, after] = parseScalar(strtrim(text(k:stop-1)), filename, lineNo); + if ~isempty(strtrim(after)) + tomlError(filename, lineNo, 'unexpected text in array'); + end + k = stop; + end + items{end+1} = item; %#ok +end +if isempty(items) + value = {}; +elseif all(cellfun(@ischar, items)) + value = items; +elseif all(cellfun(@(x) isnumeric(x) && isscalar(x), items)) + value = cell2mat(items); +elseif all(cellfun(@islogical, items)) + value = cell2mat(items); +else + tomlError(filename, lineNo, 'arrays must hold values of one type'); +end +end + +function [value, rest] = parseScalar(text, filename, lineNo) +token = regexp(text, '^[^\s,\]]+', 'match', 'once'); +rest = text(numel(token)+1:end); +switch token + case 'true' + value = true; + case 'false' + value = false; + case {'inf', '+inf'} + value = Inf; + case '-inf' + value = -Inf; + case {'nan', '+nan', '-nan'} + value = NaN; + otherwise + clean = strrep(token, '_', ''); + if ~isempty(regexp(clean, '^[+-]?(0|[1-9][0-9]*)$', 'once')) || ... + ~isempty(regexp(clean, '^[+-]?(0|[1-9][0-9]*)(\.[0-9]+)?([eE][+-]?[0-9]+)?$', 'once')) + value = str2double(clean); + elseif ~isempty(regexp(token, '^\d{4}-\d{2}-\d{2}', 'once')) + tomlError(filename, lineNo, 'dates are not supported'); + else + tomlError(filename, lineNo, sprintf('cannot read value "%s"; strings need quotes', token)); + end +end +end + +function tomlError(filename, lineNo, message) +error('GECKO:readAdapterToml', '%s, line %d: %s', filename, lineNo, message); +end diff --git a/src/model_adapter/writeAdapterToml.m b/src/model_adapter/writeAdapterToml.m new file mode 100644 index 00000000..68991a4f --- /dev/null +++ b/src/model_adapter/writeAdapterToml.m @@ -0,0 +1,143 @@ +function writeAdapterToml(data, filename, header) +% writeAdapterToml Write a struct as a model adapter TOML file. +% +% Writes the subset of TOML that readAdapterToml reads: values first, +% then each nested struct as a [table] and each struct array as an array +% of tables ([[name]]). +% +% Parameters +% ---------- +% data : struct +% values may be char or string scalars, numeric or logical scalars or +% vectors, cell arrays of char, structs and struct arrays. +% filename : char +% path of the TOML file to write; an existing file is overwritten. +% header : char or cell, optional +% comment lines written at the top of the file (without '#'). +% +% Examples +% -------- +% writeAdapterToml(struct('sigma',0.5), 'model_adapter.toml', ... +% {'Adapter for ecYeastGEM'}); +% +% See also +% -------- +% readAdapterToml, convertAdapterToToml + +if nargin < 3 + header = {}; +elseif ischar(header) || isstring(header) + header = cellstr(header); +end + +out = {}; +for k = 1:numel(header) + out{end+1} = ['# ' header{k}]; %#ok +end +if ~isempty(header) + out{end+1} = ''; +end +out = writeTable(out, data, {}); + +fid = fopen(filename, 'w'); +if fid < 0 + error('GECKO:writeAdapterToml', 'Cannot write %s', filename); +end +fprintf(fid, '%s\n', out{:}); +fclose(fid); +end + +function out = writeTable(out, s, prefix) +fields = fieldnames(s); +tables = {}; +for k = 1:numel(fields) + value = s.(fields{k}); + if isstruct(value) + tables{end+1} = fields{k}; %#ok + elseif isempty(value) && ~iscell(value) && ~ischar(value) + continue % unset value; TOML has no null + else + out{end+1} = [fields{k} ' = ' formatValue(value, strjoin([prefix fields(k)], '.'))]; %#ok + end +end +for k = 1:numel(tables) + value = s.(tables{k}); + name = strjoin([prefix tables(k)], '.'); + if numel(value) == 1 + out{end+1} = ''; %#ok + out{end+1} = ['[' name ']']; %#ok + out = writeTable(out, value, [prefix tables(k)]); + else + for e = 1:numel(value) + out{end+1} = ''; %#ok + out{end+1} = ['[[' name ']]']; %#ok + out = writeTable(out, value(e), [prefix tables(k)]); + end + end +end +end + +function text = formatValue(value, name) +if isstring(value) && isscalar(value) + value = char(value); +end +if ischar(value) + text = quote(value); +elseif iscell(value) + if ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), value)) + error('GECKO:writeAdapterToml', '%s: only cell arrays of text can be written', name); + end + parts = cellfun(@(x) quote(char(x)), value, 'UniformOutput', false); + text = ['[' strjoin(parts(:)', ', ') ']']; +elseif islogical(value) || isnumeric(value) + if isscalar(value) + text = formatScalar(value); + else + parts = arrayfun(@formatScalar, value(:)', 'UniformOutput', false); + text = ['[' strjoin(parts, ', ') ']']; + end +else + error('GECKO:writeAdapterToml', '%s: values of class %s cannot be written', name, class(value)); +end +end + +function text = formatScalar(x) +if islogical(x) + if x + text = 'true'; + else + text = 'false'; + end +elseif isinf(x) + if x > 0 + text = 'inf'; + else + text = '-inf'; + end +elseif isnan(x) + text = 'nan'; +elseif x == round(x) && abs(x) < 1e15 + text = sprintf('%d', x); +else + text = sprintf('%.17g', x); + % Use the shortest form that reads back to the same double. + for p = 1:17 + candidate = sprintf('%.*g', p, x); + if str2double(candidate) == x + text = candidate; + break + end + end + if isempty(regexp(text, '[.eE]', 'once')) + text = [text '.0']; + end +end +end + +function text = quote(s) +s = strrep(s, '\', '\\'); +s = strrep(s, '"', '\"'); +s = strrep(s, sprintf('\t'), '\t'); +s = strrep(s, newline, '\n'); +text = ['"' s '"']; +end diff --git a/src/utilities/createGECKOproject.m b/src/utilities/createGECKOproject.m index e1d127fb..5204c1be 100644 --- a/src/utilities/createGECKOproject.m +++ b/src/utilities/createGECKOproject.m @@ -8,23 +8,30 @@ function createGECKOproject(varargin) % -------------------- % name : char % a name for the folder structure used in GECKO. Also creates a basic -% adapter class, which must be manually adjusted. If not defined, a +% model adapter, which must be manually adjusted. If not defined, a % dialog box will appear. % path : char % a path where to create the folder. If not defined, a dialog box will % appear. +% adapterFormat : char +% 'toml' (default) writes model_adapter.toml, which GECKO and geckopy +% both read (see TomlAdapter); 'class' writes an adapter class +% Adapter.m instead. % % Examples % -------- % % optional arguments may be given positionally or as name-value pairs: % createGECKOproject(name, path); % createGECKOproject('name', name); +% createGECKOproject('name', name, 'adapterFormat', 'class'); p = parseGECKOargs(varargin, { ... 'name', []; ... - 'path', []}); + 'path', []; ... + 'adapterFormat', 'toml'}); name = p.name; path = p.path; +adapterFormat = validatestring(p.adapterFormat, {'toml','class'}); if isempty(name) prompt = {'Please provide a project name (e.g. ecYeastGEM)'}; @@ -51,9 +58,15 @@ function createGECKOproject(varargin) fclose(fid); end - % Read the template adapter class - fid = fopen(fullfile(findGECKOroot, 'src', ... - 'model_adapter', 'adapterTemplate.m')); + % Read the template adapter + if strcmp(adapterFormat, 'toml') + template = 'adapterTemplate.toml'; + filename = fullfile(path, name, 'model_adapter.toml'); + else + template = 'adapterTemplate.m'; + filename = fullfile(path, name, [name 'Adapter.m']); + end + fid = fopen(fullfile(findGECKOroot, 'src', 'model_adapter', template)); f = fread(fid, '*char')'; fclose(fid); @@ -62,8 +75,7 @@ function createGECKOproject(varargin) f = strrep(f, 'KEY_PATH', path); f = strrep(f, 'KEY_NAME', name); - % Save the class file - filename = fullfile(path, name, [name 'Adapter.m']); + % Save the adapter fid = fopen(filename, 'w'); fwrite(fid, f); fclose(fid); diff --git a/src/utilities/upgradeGECKOproject.m b/src/utilities/upgradeGECKOproject.m new file mode 100644 index 00000000..56a22661 --- /dev/null +++ b/src/utilities/upgradeGECKOproject.m @@ -0,0 +1,309 @@ +function report = upgradeGECKOproject(projectPath, varargin) +% upgradeGECKOproject Bring a GECKO 3 project to the GECKO 4 layout. +% +% Lists, and with 'dryRun', false carries out, the steps that bring a +% project made with GECKO 3 (or an earlier GECKO 4) to the current layout: +% +% 1. adapter: an adapter class without model_adapter.toml gets one +% (convertAdapterToToml). Methods the class overrides are listed: they +% need carrying over by hand. The class itself stays. +% 2. custom kcats: data/customKcats.tsv becomes data/kcats/custom.tsv +% (convertCustomKcats). +% 3. stored predictions: data/DLKcat.tsv and stored OpenKineticsPredictor +% results become kcat source files (kcatsFromDLKcat, kcatsFromOKP with +% 'useStored'), without running anything. +% Steps 2 and 3 need the full ecModel the custom kcats and predictions are +% for ('ecModel'); without it they are listed and skipped. +% 4. saved ecModels: models/*.yml ecModels made with GECKO 3 get their +% protein usage and pool reactions turned forward (upgradeEcModel). +% 5. project_format = 4 is written to model_adapter.toml. +% 6. scripts: lines of the project's .m files that call renamed or replaced +% functions are listed, not changed. +% +% A file that is replaced or converted is first moved to +% legacy// in the project, keeping its place in the folder +% tree. Steps that are already done are left out, so the function can run +% again. geckopy has the same as `geckopy upgrade` (upgrade_project). +% +% Parameters +% ---------- +% projectPath : char +% the project folder. +% +% Name-Value Arguments +% -------------------- +% dryRun : logical +% only list the steps (default true). +% ecModel : struct +% the ecModel the stored predictions were made for (step 3). +% +% Returns +% ------- +% report : table +% one row per step: step, status ('to do', 'done', 'skipped', 'failed', +% 'by hand') and note; script lines are listed one per row. +% +% Examples +% -------- +% upgradeGECKOproject(projectPath) % see what it would do +% upgradeGECKOproject(projectPath, 'dryRun', false, 'ecModel', ecModel) +% +% See also +% -------- +% convertAdapterToToml, convertCustomKcats, upgradeEcModel, createGECKOproject + +checkOptions(varargin, {'dryRun','ecModel'}, 'upgradeGECKOproject'); +p = parseGECKOargs(varargin, {'dryRun', true; 'ecModel', []}); +projectPath = char(projectPath); +if ~isfolder(projectPath) + error('upgradeGECKOproject:path', 'No folder %s.', projectPath) +end +apply = ~p.dryRun; +legacy = fullfile(projectPath, 'legacy', char(datetime('now', 'Format', 'yyyy-MM-dd'))); +toml = fullfile(projectPath, 'model_adapter.toml'); +rows = cell(0, 3); + function add(step, status, note) + rows(end+1, :) = {step, status, note}; + end + function keepOriginal(file) + % Move a file to legacy//, at its place in the folder tree. + rel = file(numel(projectPath)+2:end); + target = fullfile(legacy, rel); + if ~isfolder(fileparts(target)) + mkdir(fileparts(target)); + end + movefile(file, target); + end +status = 'to do'; +if apply + status = 'done'; +end + +% 1. Adapter class -> model_adapter.toml +if ~isfile(toml) + classFile = adapterClass(projectPath); + if isempty(classFile) + add('adapter', 'by hand', 'no model_adapter.toml and no adapter class; see createGECKOproject'); + else + note = sprintf('%s -> model_adapter.toml', relative(classFile, projectPath)); + if apply + r = convertAdapterToToml(classFile, toml); + if ~isempty(r.methods) + add('adapter methods', 'by hand', ['carry over: ' strjoin(r.methods, ', ')]); + end + end + add('adapter', status, note); + end +end + +% 2. customKcats.tsv -> data/kcats/custom.tsv +custom = fullfile(projectPath, 'data', 'customKcats.tsv'); +customOut = fullfile(projectPath, 'data', 'kcats', 'custom.tsv'); +if isfile(custom) && ~isfile(customOut) + note = 'data/customKcats.tsv -> data/kcats/custom.tsv'; + if isempty(p.ecModel) + add('custom kcats', 'skipped', [note '; give the ecModel they are for (''ecModel'')']); + else + if apply + [~, r] = convertCustomKcats(p.ecModel, 'customKcats', custom, 'outFile', customOut, ... + 'modelAdapter', projectAdapter(projectPath)); + keepOriginal(custom); + note = sprintf('%s (%d rows)', note, r.rows); + end + add('custom kcats', status, note); + end +end + +% 3. Stored predictions -> kcat source files +stored = {}; +if isfile(fullfile(projectPath, 'data', 'DLKcat.tsv')) && ~isfile(fullfile(projectPath, 'data', 'kcats', 'dlkcat.tsv')) + stored{end+1} = 'dlkcat'; +end +okpFiles = dir(fullfile(projectPath, 'data', 'OKP_output*.csv')); +for k = 1:numel(okpFiles) + method = okpMethod(projectPath, okpFiles(k).name); + if ~isempty(method) + name = ['okp_' lower(regexprep(regexprep(method, '[^A-Za-z0-9]+', '_'), '^_+|_+$', ''))]; + if ~isfile(fullfile(projectPath, 'data', 'kcats', [name '.tsv'])) + stored{end+1} = method; %#ok + end + end +end +stored = unique(stored, 'stable'); +if ~isempty(stored) + note = ['stored predictions -> data/kcats: ' strjoin(stored, ', ')]; + if isempty(p.ecModel) + add('predictions', 'skipped', [note '; give the ecModel they were made for (''ecModel'')']); + else + if apply + adapter = projectAdapter(projectPath); + for k = 1:numel(stored) + try + if strcmp(stored{k}, 'dlkcat') + kcatsFromDLKcat(p.ecModel, 'modelAdapter', adapter); + else + kcatsFromOKP(p.ecModel, 'method', stored{k}, 'useStored', true, 'modelAdapter', adapter); + end + add('predictions', status, ['stored predictions -> data/kcats: ' stored{k}]); + catch err + add('predictions', 'failed', sprintf('%s: %s', stored{k}, err.message)); + end + end + else + add('predictions', status, note); + end + end +end + +% 4. Saved ecModels: protein reactions turned forward +models = dir(fullfile(projectPath, 'models', '*.yml')); +for k = 1:numel(models) + file = fullfile(models(k).folder, models(k).name); + if ~contains(fileread(file), 'prot_pool') + continue + end + try + model = readYAMLmodel(file); + catch err + add('saved ecModel', 'failed', sprintf('%s: %s', relative(file, projectPath), err.message)); + continue + end + if isfield(model.annotation, 'gecko_format') && str2double(model.annotation.gecko_format) > 4 + add('saved ecModel', 'failed', sprintf('%s: ecModel format %s is newer than this GECKO', ... + relative(file, projectPath), model.annotation.gecko_format)); + continue + end + [model, changed] = upgradeEcModel(model); + if isempty(changed) + continue + end + if apply + model.annotation.generator = ['GECKO ' geckoVersion()]; + keepOriginal(file); + writeYAMLmodel(model, file); + end + add('saved ecModel', status, sprintf('%s: %d protein reactions turned forward', ... + relative(file, projectPath), numel(changed))); +end + +% 5. project_format in model_adapter.toml +adapterRow = strcmp(rows(:, 1), 'adapter') & ~strcmp(rows(:, 2), 'by hand'); +if isfile(toml) || any(adapterRow) + if ~isfile(toml) || isempty(regexp(fileread(toml), '(?m)^\s*project_format\s*=', 'once')) + if apply + text = fileread(toml); + fid = fopen(toml, 'w', 'n', 'UTF-8'); + fprintf(fid, 'project_format = 4\n%s', text); + fclose(fid); + end + add('project format', status, 'project_format = 4 in model_adapter.toml'); + end +end + +% 6. Scripts that call renamed or replaced functions +renamed = { ... + 'enzymeUsage', 'getEnzymeUsage'; 'pfbaEnzymes', 'getPfbaEnzymes'; ... + 'selectKcatValue', 'assignKcatValues'; 'startGECKOproject', 'createGECKOproject'; ... + 'updateGECKOdoc', 'buildGECKOdoc'; 'copyECtoGEM', 'applyECcodes'; ... + 'addCarbonNum', 'fillCarbonNum'; 'updateprior', 'updatePrior'; ... + 'mergeDLKcatAndFuzzyKcats', 'mergeKcats'; ... + 'fuzzyKcatMatching', 'kcatsFromBrenda (or kcatsFromECTree), then assignKcats'; ... + 'readDLKcatOutput', 'kcatsFromDLKcat, then assignKcats'; ... + 'readOpenKineticsPredictorOutput', 'kcatsFromOKP, then assignKcats'; ... + 'writeOpenKineticsPredictorInput', 'kcatsFromOKP'; ... + 'applyCustomKcats', 'data/kcats/custom.tsv and assignKcats'}; +scripts = dir(fullfile(projectPath, '**', '*.m')); +for k = 1:numel(scripts) + file = fullfile(scripts(k).folder, scripts(k).name); + if startsWith(file, fullfile(projectPath, 'legacy')) + continue + end + lines = strsplit(fileread(file), {'\r\n', '\n'}); + for r = 1:size(renamed, 1) + hit = find(~cellfun(@isempty, regexp(lines, ['(? %s', relative(file, projectPath), h, ... + renamed{r, 1}, renamed{r, 2})); + end + end +end + +report = cell2table(rows, 'VariableNames', {'step', 'status', 'note'}); +if isempty(rows) + fprintf('%s has the current GECKO 4 layout.\n', projectPath); +else + disp(report) + if ~apply && any(strcmp(rows(:, 2), 'to do')) + fprintf('Run upgradeGECKOproject(projectPath, ''dryRun'', false) to carry out the steps; originals go to %s.\n', legacy); + end +end +end + +function adapter = projectAdapter(projectPath) +% The project's adapter: from model_adapter.toml, or its adapter class. +if isfile(fullfile(projectPath, 'model_adapter.toml')) + adapter = TomlAdapter(projectPath); +else + adapter = ModelAdapterManager.getAdapter(adapterClass(projectPath)); + adapter.params.path = projectPath; +end +end + +function file = adapterClass(projectPath) +% The adapter class in the project folder, or '' when there is none. +file = ''; +candidates = dir(fullfile(projectPath, '*.m')); +for k = 1:numel(candidates) + f = fullfile(candidates(k).folder, candidates(k).name); + if ~isempty(regexp(fileread(f), '(?m)^\s*classdef\s+\w+\s*<\s*ModelAdapter', 'once')) + file = f; + return + end +end +end + +function method = okpMethod(projectPath, outName) +% The OKP method of a stored result: from its own job file +% (OKP_job_.txt), or from OKP_job.txt for the shared OKP_output.csv. +method = ''; +if strcmp(outName, 'OKP_output.csv') + jobFile = fullfile(projectPath, 'data', 'OKP_job.txt'); +else + jobFile = fullfile(projectPath, 'data', ['OKP_job_' regexprep(outName, '^OKP_output_|\.csv$', '') '.txt']); +end +if ~isfile(jobFile) + return +end +tok = regexp(fileread(jobFile), '(?m)^method:\s*(\S+)', 'tokens', 'once'); +if ~isempty(tok) + method = tok{1}; +end +end + +function r = relative(file, projectPath) +r = file(numel(projectPath)+2:end); +end + +function checkOptions(args, names, functionName) +% Options are name-value pairs with known names, so a misspelled option is +% an error instead of being taken as a positional argument. +id = [functionName ':arguments']; +given = args(1:2:end); +if mod(numel(args), 2) ~= 0 || ~all(cellfun(@(x) ischar(x) || (isstring(x) && isscalar(x)), given)) + error(id, 'Options of %s are name-value pairs. Options: %s.', functionName, strjoin(names, ', ')) +end +unknown = setdiff(cellfun(@char, given, 'UniformOutput', false), names); +if ~isempty(unknown) + error(id, 'Unknown option of %s: %s. Options: %s.', functionName, strjoin(unknown, ', '), ... + strjoin(names, ', ')) +end +end + +function v = geckoVersion() +file = fullfile(findGECKOroot, 'version.txt'); +if isfile(file) + v = strtrim(fileread(file)); +else + v = 'unknown'; +end +end diff --git a/test/VerificationMatrix.tsv b/test/VerificationMatrix.tsv index fad92a5a..6457127e 100644 --- a/test/VerificationMatrix.tsv +++ b/test/VerificationMatrix.tsv @@ -1,36 +1,83 @@ Function/File (in src) Verification Comments BrendaParser/* Not explicitly tested - The code has existed for a long time -change_model/applyComplexData.m tc0003, tc0004 -change_model/applyKcatConstraints.m tc0011 +change_model/applyComplexData.m tc0003, tc0004, tc0103, tc0501 +change_model/applyKcatConstraints.m tc0011, tc0215, tc0235, tc0238, tc0250 +change_model/findMetSmiles.m tc0012, tc0407, tc0408 +change_model/applyKcatConstraints.m tc0011, tc0215, tc0235, tc0238, tc0250, tc0512 change_model/findMetSmiles.m tc0012 change_model/getComplexData.m tc0003, tc0004 - File download not covered by test cases but is tested manually and works. -change_model/makeEcModel.m tc0001, tc0002 +change_model/makeEcModel.m tc0001, tc0002, tc0210, tc0212, tc0233, tc0234 change_model/setProtPoolSize.m tc0005 -change_model/getKcatAcrossIsoenzymes.m tc0011 -change_model/applyCustomKcats.m -gather_kcats/fuzzyKcatMatching.m tc0010 -gather_kcats/getStandardKcat.m -gather_kcats/mergeDlkcatAndFuzzyKcats.m tc0011 -gather_kcats/readDLKcatOutput.m tcm0001, tcm0002 - The test doesn't really check the function, only that some output is read +change_model/getKcatAcrossIsoenzymes.m tc0011, tc0252 +change_model/getSubsetEcModel.m tc0258, tc0259 +change_model/applyCustomKcats.m tc0227, tc0228, tc0229, tc0230 +enzyme_usage/getEnzymeUsage.m tc0507, tc0508 +enzyme_usage/reportEnzymeUsage.m tc0508, tc0509 +gather_kcats/fuzzyKcatMatching.m tc0010, tc0223, tc0224, tc0225, tc0226, tc0231, tc0239 +gather_kcats/getStandardKcat.m tc0256, tc0257, tc0309, tc0310 +gather_kcats/mergeDlkcatAndFuzzyKcats.m tc0011; tc0241 +gather_kcats/readDLKcatOutput.m tcm0001, tcm0002, tc0303, tc0304 - The test doesn't really check the function, only that some output is read gather_kcats/runDLKcat.m tcm0001, tcm0002 - The test doesn't really check the function, only that we get something -gather_kcats/assignKcatValues.m tc0011 - we did not test all possible parameterizations here -gather_kcats/writeDLKcatInput.m partly by tc0011 +gather_kcats/assignKcatValues.m tc0011 - we did not test all possible parameterizations here; also tc0104, tc0311 +gather_kcats/writeDLKcatInput.m partly by tc0011, tc0305 +gather_kcats/getEcRxnKeys.m tc0070, tc0076 +gather_kcats/saveKcatSource.m tc0071, tc0073, tc0076, tc0078 +gather_kcats/loadKcatSource.m tc0071, tc0072, tc0073, tc0076, tc0077, tc0078, tc0302 +gather_kcats/kcatsFromBrenda.m tc0074, tc0078, tc0226 +gather_kcats/kcatsFromDLKcat.m tc0074, tc0078 - reads an existing DLKcat output; running DLKcat needs Docker +gather_kcats/kcatsFromOKP.m tc0075 - reads a stored result; submitting needs the OKP service +gather_kcats/collectKcats.m tc0079, tc0080, tc0081, tc0083, tc0087, tc0088, tc0089, tc0090, tc0098, tc0300 +gather_kcats/assignKcats.m tc0079, tc0083 +gather_kcats/updateKcatSources.m tc0082, tc0087 +gather_kcats/kcatAssignmentConfig.m tc0079, tc0081, tc0083, tc0087, tc0088, tc0089, tc0090, tc0306 +gather_kcats/loadBrendaMeasurements.m tc0085 +gather_kcats/ecTreeEstimate.m tc0084, tc0307 +gather_kcats/kcatsFromECTree.m tc0086, tc0087, tc0308 +gather_kcats/kcatAssignmentConfig.m tc0079, tc0081, tc0083, tc0087, tc0088, tc0089, tc0090 +gather_kcats/loadBrendaMeasurements.m tc0085, tc0403 +gather_kcats/ecTreeEstimate.m tc0084 +gather_kcats/kcatsFromECTree.m tc0086, tc0087 +gather_kcats/kcatsFromHomologs.m tc0095, tc0096 +gather_kcats/extractEnzymeSubstratePairs.m tc0096, tc0015 +gather_kcats/convertCustomKcats.m tc0091, tc0092, tc0094 +change_model/upgradeEcModel.m tc0093, tc0094, tc0099 +io/loadFluxData.m tc0506 +io/loadProtData.m tc0101, tc0102, tc0260 +change_model/addNewRxnsToEC.m tc0211, tc0232, tc0237, tc0500 +change_model/mapRxnsToConv.m tc0213 +flux_analysis/ecFVA.m tc0214 +flux_analysis/ecFSEOF.m tc0100, tc0236 +limit_proteins/calculateFfactor.m tc0502 +limit_proteins/constrainEnzConcs.m tc0503 +limit_proteins/constrainFluxData.m tc0505 +limit_proteins/fillEnzConcs.m tc0504 +limit_proteins/relaxProteomicsGreedy.m tc0511 +utilities/upgradeGECKOproject.m tc0094, tc0099 +gather_kcats/readOpenKineticsPredictorOutput.m tc0030, tc0069 gather_kcats/reviewKcatAssignment.m Has only been tested by running it manually, not tested by test cases gather_kcats/ecStatsFromBrenda.m Not verified against real BRENDA data in this environment -- see its own TODO comment +gather_kcats/mergeKcats.m tc0240, tc0301 +gather_kcats/reviewKcatAssignment.m tc0402 (the ec-maximum check); the other checks have only been tested by running it manually +gather_kcats/ecStatsFromBrenda.m tc0400, tc0401 - not verified against a real BRENDA pull +gather_kcats/mergeKcats.m tc0240 get_enzyme_data/calculateMW.m Not explicitly tested - The code has existed for a long time -get_enzyme_data/findECInDB.m Called from getECfromDatabase - tested when that function is tested. -get_enzyme_data/getECfromDatabase.m tc0007 - does not test download of the databases - this is tested in the manual workflows for Yeast-GEM and Human-GEM +get_enzyme_data/findECInDB.m Called from getECfromDatabase - tested when that function is tested; also tc0242, tc0243, tc0244, tc0245, tc0246 +get_enzyme_data/getECfromDatabase.m tc0007, tc0404, tc0405, tc0406, tc0409 - does not test download of the databases - this is tested in the manual workflows for Yeast-GEM and Human-GEM get_enzyme_data/getECfromGEM.m tc0006 -get_enzyme_data/getECstring.m Called from findECInDB - tested when that function is tested. -download_databases/loadBRENDAdata.m Called from fuzzyKcatMatching - tested when that function is tested. +get_enzyme_data/getECstring.m Called from findECInDB - tested when that function is tested; also tc0246 +download_databases/loadBRENDAdata.m Called from fuzzyKcatMatching - tested when that function is tested; also tc0105, tc0220, tc0221, tc0222 +download_databases/fetchBrendaAsset.m tc0085 download_databases/loadDatabases.m Called from getECfromDatabase - tested when that function is tested. +kcat_tuning/evotune/bestParsimonious.m tc0600 kcat_tuning/evotune/* Has only been tested by running it manually, not tested by test cases +kcat_tuning/fillCarbonNum.m tc0055 (deprecated-alias check only), tc0601, tc0602 +kcat_tuning/evotune/* resolveTunableContext by tc0312; the rest has only been tested by running it manually, not tested by test cases kcat_tuning/fillCarbonNum.m tc0055 (deprecated-alias check only, not a real usage test) kcat_tuning/findTopLimitations.m Not explicitly tested - The code has existed for a long time -kcat_tuning/sensitivityTuning.m tcm0001 -kcat_tuning/sigmaFitter.m Not explicitly tested - The code has existed for a long time +kcat_tuning/sensitivityTuning.m tcm0001, tc0251, tc0253, tc0254 +kcat_tuning/sigmaFitter.m tc0020, tc0255 kcat_tuning/topUsedEnzymes.m Not explicitly tested - The code has existed for a long time Not sure this works anymore - written for the old model structure? -kcat_tuning/truncateValues.m Not explicitly tested - The code has existed for a long time +kcat_tuning/truncateValues.m tc0510 limit_proteins/constrainProtConcs.m tc0013 limit_proteins/findLimitingUBs.m Not explicitly tested - The code has existed for a long time Probably not relevant anymore, remove? limit_proteins/fitGAM.m @@ -38,15 +85,27 @@ limit_proteins/flexibilizeProteins.m Not explicitly tested - The code has existe limit_proteins/readProteomics.m tc0013 limit_proteins/flexibilizeProtConcs.m tc0013 limit_proteins/getConcControlCoeffs.m tc0013 +limit_proteins/flexibilizeEnzConcs.m tc0013, tc0273, tc0274, tc0275, tc0276 (perComplex option) +limit_proteins/getComplexFamilies.m tc0262, tc0263, tc0264, tc0265, tc0266 +limit_proteins/levelComplexConcs.m tc0267, tc0268, tc0269, tc0270, tc0271, tc0272 limit_proteins/updateProtPool.m model_adapter/ModelAdapter.m Base class for adapters, not explicitly tested. -model_adapter/ModelAdapterManager.m tc0008 +model_adapter/ModelAdapterManager.m tc0008, tc0067 +model_adapter/readAdapterToml.m tc0061, tc0062 +model_adapter/writeAdapterToml.m tc0063 +model_adapter/loadAdapterParams.m tc0064, tc0065 +model_adapter/convertAdapterToToml.m tc0066 +model_adapter/TomlAdapter.m tc0066, tc0067 +model_adapter/adapterParameters.tsv tc0064, tc0065 +model_adapter/adapterTemplate.toml tc0068 utilities/* Not explicitly tested - The code has existed for a long time. There are a lot of functions in here, unclear which of them are still useful and functional. io/loadConventionalGEM.m tc0009 -io/loadEcModel.m tc0009 -io/saveEcModel.m tc0009 +io/loadEcModel.m tc0009, tc0099 +io/saveEcModel.m tc0009, tc0099, tc0603 +io/loadEcModel.m tc0009, tc0099, tc0700 +io/saveEcModel.m tc0009, tc0099, tc0700 tutorials/tutorial_Human-GEM/HumanGEMAdapter.m tcm0002 - does not test all aspects of the adapter, but some. -tutorials/tutorial_yeast-GEM/YeastGEMAdapter.m tcm0001 - does not test all aspects of the adapter, but some. +tutorials/full_ecModel/model_adapter.toml tcm0001 - does not test all aspects of the adapter, but some. tutorials/tutorial_yeast-GEM/code/changeMedia_batch.m Not explicitly tested - The code has existed for a long time tutorials/tutorial_yeast-GEM/code/getModelParameters_obsolete.m Deprecated tutorials/tutorial_yeast-GEM/code/manualModifications.m Deprecated diff --git a/test/manual_tests/TestYeastGEMSimpleWorkflow.m b/test/manual_tests/TestYeastGEMSimpleWorkflow.m index f641ad2d..70c312cb 100644 --- a/test/manual_tests/TestYeastGEMSimpleWorkflow.m +++ b/test/manual_tests/TestYeastGEMSimpleWorkflow.m @@ -2,7 +2,7 @@ GECKORoot = findGECKOroot(); -yeastAdapter = ModelAdapterManager.getAdapter(fullfile(GECKORoot, 'tutorials', 'full_ecModel', 'YeastGEMAdapter.m')); +yeastAdapter = ModelAdapterManager.getAdapter(fullfile(GECKORoot, 'tutorials', 'full_ecModel')); yeastGEM = readYAMLmodel(fullfile(yeastAdapter.getParameters().path,'models','yeast-GEM.yml')); %Full model diff --git a/test/unit_tests/adapterTomlTests.m b/test/unit_tests/adapterTomlTests.m new file mode 100644 index 00000000..2bfb1cf3 --- /dev/null +++ b/test/unit_tests/adapterTomlTests.m @@ -0,0 +1,237 @@ +%run this test case with the command +%results = runtests('adapterTomlTests.m') + +function tests = adapterTomlTests + tests = functiontests(localfunctions); +end + +function testReadAdapterToml_tc0061(testCase) + % Every TOML feature that model adapter files use. + file = writeTemp({ ... + '# comment', ... + 'name = "a \"quoted\" # not a comment" # comment', ... + 'literal = ''C:\path''', ... + 'int = 559_292', ... + 'float = 2.5e-1', ... + 'yes = true', ... + 'list = ["a", "b",', ... + ' "c"] # over two lines', ... + 'nums = [0.4, 0.2, 0.1]', ... + 'empty = []', ... + '', ... + '[kegg]', ... + 'id = "sce"', ... + '', ... + '[evotune.source_groups.okp]', ... + 'sources = ["OKP"]', ... + 'match_okp = true', ... + '', ... + '[[stage]]', ... + 'action = "select"', ... + '[[stage]]', ... + 'action = "fill"', ... + 'sources = ["isozymes"]'}); + d = readAdapterToml(file); + verifyEqual(testCase, d.name, 'a "quoted" # not a comment') + verifyEqual(testCase, d.literal, 'C:\path') + verifyEqual(testCase, d.int, 559292) + verifyEqual(testCase, d.float, 0.25) + verifyEqual(testCase, d.yes, true) + verifyEqual(testCase, d.list, {'a','b','c'}) + verifyEqual(testCase, d.nums, [0.4 0.2 0.1]) + verifyEqual(testCase, d.empty, {}) + verifyEqual(testCase, d.kegg.id, 'sce') + verifyEqual(testCase, d.evotune.source_groups.okp.sources, {'OKP'}) + verifyTrue(testCase, d.evotune.source_groups.okp.match_okp) + verifyEqual(testCase, numel(d.stage), 2) + verifyEqual(testCase, d.stage(2).action, 'fill') + verifyEqual(testCase, d.stage(2).sources, {'isozymes'}) +end + +function testReadAdapterTomlErrors_tc0062(testCase) + % Unsupported TOML stops with the line number. + verifyError(testCase, @() readAdapterToml(writeTemp({'x = { a = 1 }'})), 'GECKO:readAdapterToml') + verifyError(testCase, @() readAdapterToml(writeTemp({'x = 2026-10-15'})), 'GECKO:readAdapterToml') + verifyError(testCase, @() readAdapterToml(writeTemp({'x = unquoted'})), 'GECKO:readAdapterToml') + verifyError(testCase, @() readAdapterToml(writeTemp({'x = 1', 'x = 2'})), 'GECKO:readAdapterToml') + try + readAdapterToml(writeTemp({'a = 1', 'b = """x"""'})); + catch err + verifySubstring(testCase, err.message, 'line 2') + end +end + +function testWriteAdapterToml_tc0063(testCase) + % What writeAdapterToml writes, readAdapterToml reads back unchanged. + s.text = 'with "quotes" and \ backslash'; + s.number = 0.1; + s.integer = 150; + s.flag = false; + s.list = {'dlkcat','brenda'}; + s.vector = [0.4 0.2]; + s.table.inner.value = 1e-8; + file = [tempname '.toml']; + writeAdapterToml(s, file, 'header'); + verifyEqual(testCase, readAdapterToml(file), s) +end + +function testLoadAdapterParamsDefaults_tc0064(testCase) + % A minimal file gets geckopy's defaults, under GECKO's field names. + folder = tempname; mkdir(folder); + writeTemp({'conv_gem = "models/x.xml"', 'org_name = "testus testus"', 'p_tot = 0.4'}, ... + fullfile(folder, 'model_adapter.toml')); + params = loadAdapterParams(folder); + verifyEqual(testCase, params.path, folder) + verifyEqual(testCase, params.convGEM, fullfile(folder, 'models/x.xml')) + verifyEqual(testCase, params.Ptot, 0.4) + verifyEqual(testCase, params.sigma, 0.5) + verifyEqual(testCase, params.kegg.ID, 'sce') + verifyEqual(testCase, params.kcatAggregation, 'max') + verifyEqual(testCase, params.evotune.kcatSources, {'dlkcat','brenda','custom'}) + verifyEqual(testCase, params.evotune.sigma0logSource, [0.4; 0.2; 0.1]) + verifyEqual(testCase, params.evotune.maxGenerations, 150) + verifyEqual(testCase, params.okp.handleLongSequences, 'truncate') + verifyEmpty(testCase, params.complex.taxonomicID) + % A misspelled key is an error, as in geckopy. + writeTemp({'conv_gem = "x.xml"', 'org_name = "x"', 'sigmaa = 1'}, fullfile(folder, 'model_adapter.toml')); + verifyError(testCase, @() loadAdapterParams(folder), 'GECKO:loadAdapterParams') +end + +function testLoadAdapterParamsSourceGroups_tc0065(testCase) + % Trust tiers with several sources and the OKP method. + folder = tempname; mkdir(folder); + writeTemp({'conv_gem = "x.xml"', 'org_name = "x"', ... + '[okp]', 'method = "EITLEM"', ... + '[evotune.source_groups.okp]', 'sources = ["OpenKineticsPredictor"]', 'match_okp = true', ... + '[evotune.source_groups.database]', 'sources = ["brenda", "okp_brenda"]', ... + '[evotune.sigma0_log_source]', 'okp = 0.25', 'database = 0.2', ... + '[matlab]', 'make_model_anaerobic = "anaerobicModel_GECKO"', ... + '[matlab.params]', 'c_UptakeExp = 0.64'}, fullfile(folder, 'model_adapter.toml')); + params = loadAdapterParams(fullfile(folder, 'model_adapter.toml')); + verifyEqual(testCase, params.evotune.kcatSources, {'OpenKineticsPredictor','EITLEM','brenda','okp_brenda'}) + verifyEqual(testCase, params.evotune.sigma0logSource, [0.25; 0.25; 0.2; 0.2]) + verifyEqual(testCase, params.matlab.makeModelAnaerobic, 'anaerobicModel_GECKO') + verifyEqual(testCase, params.c_UptakeExp, 0.64) +end + +function testConvertAdapterToToml_tc0066(testCase) + % Converting an adapter class and loading the TOML gives the same + % parameters back. + geckoPath = findGECKOroot; + legacyFolder = tempname; mkdir(legacyFolder); + writeTemp(legacyAdapterClass(), fullfile(legacyFolder, 'LegacyFixtureAdapter.m')); + adapters = {fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m'), ... + fullfile(legacyFolder,'LegacyFixtureAdapter.m')}; + for k = 1:numel(adapters) + original = ModelAdapterManager.getAdapter(adapters{k}); + folder = tempname; mkdir(folder); + file = fullfile(folder, 'model_adapter.toml'); + report = convertAdapterToToml(original, file); + verifyTrue(testCase, any(strcmp(report.methods, 'getSpontaneousReactions'))) + converted = TomlAdapter(file); + expected = original.params; + actual = converted.params; + % The project folder is where the TOML file is; the model path is + % relative to it. + [~, convName] = fileparts(expected.convGEM); + [~, convName2] = fileparts(actual.convGEM); + verifyEqual(testCase, convName2, convName) + expected = rmfield(expected, {'path','convGEM'}); + verifyEqual(testCase, keepFields(actual, expected), expected) + end + verifyEqual(testCase, report.unmapped, {'c_UptakeExp'}) +end + +function lines = legacyAdapterClass() +% An adapter class as written for GECKO 3 and 4: evotune trust tiers and a +% parameter that geckopy does not know. +lines = { ... + 'classdef LegacyFixtureAdapter < ModelAdapter', ... + ' methods', ... + ' function obj = LegacyFixtureAdapter()', ... + ' obj.params.path = fileparts(mfilename(''fullpath''));', ... + ' obj.params.convGEM = fullfile(obj.params.path,''models'',''human-GEM.yml'');', ... + ' obj.params.sigma = 0.1;', ... + ' obj.params.Ptot = 0.505717472;', ... + ' obj.params.f = 0.412;', ... + ' obj.params.gR_exp = 0.020663429;', ... + ' obj.params.c_UptakeExp = 0.641339301;', ... + ' obj.params.org_name = ''homo sapiens'';', ... + ' obj.params.kcatAggregation = ''median'';', ... + ' obj.params.complex.taxonomicID = 9606;', ... + ' obj.params.kegg.ID = ''hsa'';', ... + ' obj.params.kegg.geneID = ''Ensembl'';', ... + ' obj.params.uniprot.type = ''proteome'';', ... + ' obj.params.uniprot.ID = ''UP000005640'';', ... + ' obj.params.uniprot.geneIDfield = ''gene_primary'';', ... + ' obj.params.uniprot.reviewed = true;', ... + ' obj.params.c_source = ''MAR09034'';', ... + ' obj.params.bioRxn = ''MAR13082'';', ... + ' obj.params.enzyme_comp = ''Cytosol'';', ... + ' obj.params.evotune.sigma0logDefault = 0.5;', ... + ' obj.params.evotune.kcatSources = {''dlkcat'',''brenda'',''custom''};', ... + ' obj.params.evotune.sigma0logSource = [0.4; 0.2; 0.1];', ... + ' obj.params.evotune.maxGrowthWeight = 2.0;', ... + ' obj.params.evotune.priorPenaltyWeight = 0.03;', ... + ' obj.params.evotune.tieIsozymes = true;', ... + ' obj.params.evotune.rmseThreshold = 0.2;', ... + ' obj.params.evotune.maxGenerations = 212;', ... + ' end', ... + ' function [spont,spontRxnNames] = getSpontaneousReactions(obj,model)', ... + ' spont = contains(model.rxnNames,''spontaneous'');', ... + ' spontRxnNames = model.rxnNames(spont);', ... + ' end', ... + ' end', ... + 'end'}; +end + +function testTomlAdapterSpontaneous_tc0067(testCase) + folder = tempname; mkdir(fullfile(folder,'data')); + writeTemp({'rxns spontaneous', 'R1 0', 'R2 1', 'R3 1'}, fullfile(folder,'data','spont.tsv')); + writeTemp({'conv_gem = "x.xml"', 'org_name = "x"', ... + '[spontaneous]', 'name_contains = "spontaneous"', 'file = "data/spont.tsv"'}, ... + fullfile(folder, 'model_adapter.toml')); + adapter = ModelAdapterManager.getAdapter(folder); + verifyClass(testCase, adapter, 'TomlAdapter') + model.rxns = {'R1';'R2';'R4';'R5'}; + model.rxnNames = {'a';'b';'spontaneous c';'d'}; + [spont, names] = adapter.getSpontaneousReactions(model); + verifyEqual(testCase, spont, [false; true; true; false]) + verifyEqual(testCase, names, {'R2';'R4'}) +end + +function testCreateGECKOprojectToml_tc0068(testCase) + % A new project gets model_adapter.toml, which loads as it is. + here = pwd; + restore = onCleanup(@() cd(here)); + root = tempname; mkdir(root); + createGECKOproject('name', 'ecTestProject', 'path', root); + folder = fullfile(root, 'ecTestProject'); + verifyTrue(testCase, isfile(fullfile(folder, 'model_adapter.toml'))) + adapter = ModelAdapterManager.getAdapter(folder); + verifyEqual(testCase, adapter.params.org_name, 'genus species') + verifyEqual(testCase, adapter.params.evotune.kcatSources, {'dlkcat','brenda','custom'}) + verifyEqual(testCase, adapter.params.spontaneous.name_contains, 'spontaneous') +end + +function s = keepFields(s, template) +% s reduced to the fields (recursively) that template has. +fields = fieldnames(s); +for k = 1:numel(fields) + if ~isfield(template, fields{k}) + s = rmfield(s, fields{k}); + elseif isstruct(s.(fields{k})) && isstruct(template.(fields{k})) + s.(fields{k}) = keepFields(s.(fields{k}), template.(fields{k})); + end +end +s = orderfields(s, template); +end + +function file = writeTemp(lines, file) +if nargin < 2 + file = [tempname '.toml']; +end +fid = fopen(file, 'w'); +fprintf(fid, '%s\n', lines{:}); +fclose(fid); +end diff --git a/test/unit_tests/brendaMeasurementsXzTests.m b/test/unit_tests/brendaMeasurementsXzTests.m new file mode 100644 index 00000000..7a9f361d --- /dev/null +++ b/test/unit_tests/brendaMeasurementsXzTests.m @@ -0,0 +1,42 @@ +%run this test case with the command +%results = runtests('brendaMeasurementsXzTests.m') + +function tests = brendaMeasurementsXzTests + tests = functiontests(localfunctions); +end + +function testLoadBrendaMeasurementsReadsXz_tc0403(testCase) + [status, ~] = system('xz --version'); + assumeEqual(testCase, status, 0) + folder = tempname(); + mkdir(folder); + cleanup = onCleanup(@() rmdir(folder, 's')); %#ok + writeMeasurements(fullfile(folder, 'measurements.tsv'), {'1.1.1.1', 5}) + % only the plain file + m = loadBrendaMeasurements('folder', folder); + verifyEqual(testCase, m.kcat, 5) + % only the compressed file + verifyEqual(testCase, system(sprintf('xz -k "%s"', fullfile(folder, 'measurements.tsv'))), 0) + delete(fullfile(folder, 'measurements.tsv')) + m = loadBrendaMeasurements('folder', folder); + verifyEqual(testCase, m.kcat, 5) + verifyEqual(testCase, m.release, 'BRENDA release 2026.1') + % both files: the compressed one is read + writeMeasurements(fullfile(folder, 'measurements.tsv'), {'1.1.1.1', 7}) + m = loadBrendaMeasurements('folder', folder); + verifyEqual(testCase, m.kcat, 5) + % neither + delete(fullfile(folder, 'measurements.tsv')) + delete(fullfile(folder, 'measurements.tsv.xz')) + verifyError(testCase, @() loadBrendaMeasurements('folder', folder), 'loadBrendaMeasurements:missing') +end + +function writeMeasurements(file, rows) + fid = fopen(file, 'w'); + fprintf(fid, '# BRENDA release 2026.1\n'); + fprintf(fid, 'ec\tsubstrate\tsubstrate_inchikey\torganism\ttaxid\tuniprot\tseq_id\tkcat\ttemperature\tph\tpmid\n'); + for i = 1:size(rows, 1) + fprintf(fid, '%s\tS\tK\tO\t1\tP1\t1\t%g\t25\t7\t1\n', rows{i, 1}, rows{i, 2}); + end + fclose(fid); +end diff --git a/test/unit_tests/brendaReviewStatsTests.m b/test/unit_tests/brendaReviewStatsTests.m new file mode 100644 index 00000000..83b98203 --- /dev/null +++ b/test/unit_tests/brendaReviewStatsTests.m @@ -0,0 +1,53 @@ +%run this test case with the command +%results = runtests('brendaReviewStatsTests.m') + +function tests = brendaReviewStatsTests + tests = functiontests(localfunctions); +end + +function testEcStatsFromBrendaMedianMaximumAndCase_tc0400(testCase) + % Per EC number: the rows and maximum of the max view, the median of the + % median view, the values of both views, and the specific-activity rows. + % The EC keys keep their case. + kcatMax = {{'1.1.1.1';'1.1.1.1';'3.5.1.n3';'3.5.1.N5'}, {'a';'b';'c';'d'}, {'o';'o';'o';'o'}, [10;4;40;7]}; + kcatMed = {{'1.1.1.1';'1.1.1.1';'1.1.1.1';'3.5.1.n3'}, {'a';'b';'e';'c'}, {'o';'o';'o';'o'}, [2;3;6;4]}; + sa = {{'4.1.1.1';'1.1.1.1'}, {'o';'o'}, [1;2], [1;1]}; + stats = ecStatsFromBrenda(kcatMax, sa, kcatMed); + verifyEqual(testCase, sort(stats.keys()), {'1.1.1.1','3.5.1.N5','3.5.1.n3','4.1.1.1'}) + s = stats('1.1.1.1'); + verifyEqual(testCase, [s.nKcat s.kcatMax s.kcatMedian s.nSa], [2 10 3 1]) + verifyEqual(testCase, s.values(:)', [2 3 4 6 10]) + s = stats('3.5.1.n3'); + verifyEqual(testCase, [s.nKcat s.kcatMax s.kcatMedian s.nSa], [1 40 4 0]) + verifyEqual(testCase, s.values(:)', [4 40]) + s = stats('3.5.1.N5'); + verifyEqual(testCase, [s.nKcat s.kcatMax s.nSa], [1 7 0]) + verifyTrue(testCase, isnan(s.kcatMedian)) + s = stats('4.1.1.1'); + verifyEqual(testCase, [s.nKcat s.nSa], [0 1]) + verifyTrue(testCase, isnan(s.kcatMax) && isnan(s.kcatMedian)) + verifyEmpty(testCase, s.values) +end + +function testEcStatsFromBrendaWithoutMedianViewWarns_tc0401(testCase) + kcatMax = {{'1.1.1.1';'1.1.1.1'}, {'a';'b'}, {'o';'o'}, [10;4]}; + verifyWarning(testCase, @() ecStatsFromBrenda(kcatMax, {[],[],[],[]}), 'ecStatsFromBrenda:noMedianView') + warning('off', 'ecStatsFromBrenda:noMedianView') + cleanup = onCleanup(@() warning('on', 'ecStatsFromBrenda:noMedianView')); %#ok + stats = ecStatsFromBrenda(kcatMax, {[],[],[],[]}); + s = stats('1.1.1.1'); + verifyTrue(testCase, isnan(s.kcatMedian)) + verifyEqual(testCase, [s.nKcat s.kcatMax], [2 10]) + verifyEqual(testCase, s.values(:)', [4 10]) +end + +function testReviewFlagsEcMaximumWithLoaderStatistics_tc0402(testCase) + % A kcat equal to the maximum of its EC, ten times the median, is flagged + % 'ec-maximum', also for an EC with a lowercase letter. + kcatMax = {{'1.1.1.1';'3.5.1.n3'}, {'a';'c'}, {'o';'o'}, [10;40]}; + kcatMed = {{'1.1.1.1';'3.5.1.n3'}, {'a';'c'}, {'o';'o'}, [2;4]}; + stats = ecStatsFromBrenda(kcatMax, {[],[],[],[]}, kcatMed); + f = reviewKcatAssignment({'R_A';'R_F'}, [10;40], {'brenda';'brenda'}, {'1.1.1.1';'3.5.1.n3'}, 'ecStats', stats); + verifyEqual(testCase, f.rxnId', {'R_A','R_F'}) + verifyTrue(testCase, all(contains(f.checks, 'ec-maximum'))) +end diff --git a/test/unit_tests/combineTests.m b/test/unit_tests/combineTests.m new file mode 100644 index 00000000..64cd4b62 --- /dev/null +++ b/test/unit_tests/combineTests.m @@ -0,0 +1,98 @@ +%run this test case with the command +%results = runtests('combineTests.m') + +function tests = combineTests + tests = functiontests(localfunctions); +end + +function testOkpPresetCombines_tc0088(testCase) + % CataPro 100 /s (similarity 30: bin <40, bias 0.2, variance 2) and + % UniKP 10 /s (similarity 50: bin 40-60, bias -0.3, variance 1): + % (1.8 * 0.5 + 1.3 * 1) / 1.5; sd sqrt(1/1.5 + 0.25) with the okp scale + % 1. geckopy's test_okp_presets has the same numbers. + [model, adapter, rxns] = buildProject('okp'); + report = updateKcatSources(model, 'dryRun', true, 'modelAdapter', adapter); + verifyEqual(testCase, report.source', {'custom', 'okp_catapro', 'okp_unikp'}) + saveKcatSource(model, okpList(rxns(1:3), 100, 30, 'CataPro'), 'okp_catapro', 'modelAdapter', adapter); + saveKcatSource(model, okpList(rxns(1), 10, 50, 'UniKP'), 'okp_unikp', 'modelAdapter', adapter); + decisions = collectKcats(model, 'modelAdapter', adapter, 'writeReport', false); + i = find(strcmp(decisions.ecRxn, rxns{1})); + verifyEqual(testCase, decisions.kcat(i), 10 ^ ((1.8 * 0.5 + 1.3) / 1.5), 'RelTol', 1e-12) + verifyEqual(testCase, decisions.source{i}, sprintf('combined (sd=%.2f, n=2)', sqrt(1/1.5 + 0.25))) + verifyEqual(testCase, decisions.stage{i}, '2') + verifyEqual(testCase, decisions.candidates(i), 2) + verifyEqual(testCase, decisions.sdLog10(i), sqrt(1/1.5 + 0.25), 'AbsTol', 1e-12) + j = find(strcmp(decisions.ecRxn, rxns{2})); + verifyEqual(testCase, decisions.kcat(j), 10 ^ 1.8, 'RelTol', 1e-12) +end + +function testEcTreeOkpPreset_tc0089(testCase) + % EC tree 10 /s (n=4, depth 4: bin ec4:3-5, bias 0.1, variance 1) and + % CataPro 100 /s (bin <40): (0.9 + 0.9) / 1.5 = 1.2; the ec_tree+okp + % scale is 2. + [model, adapter, rxns] = buildProject('ec_tree_okp'); + saveKcatSource(model, okpList(rxns(1), 100, 30, 'CataPro'), 'okp_catapro', 'modelAdapter', adapter); + tree = struct('source', 'ec_tree', 'rxns', {rxns(1)}, 'kcats', 10, 'detail', {{'n=4; depth=4'}}); + saveKcatSource(model, tree, 'ec_tree', 'modelAdapter', adapter); + decisions = collectKcats(model, 'modelAdapter', adapter, 'writeReport', false); + i = find(strcmp(decisions.ecRxn, rxns{1})); + verifyEqual(testCase, decisions.kcat(i), 10 ^ 1.2, 'RelTol', 1e-12) + verifyEqual(testCase, decisions.sdLog10(i), sqrt(1/1.5 + 0.25) * 2, 'AbsTol', 1e-12) + verifyEqual(testCase, decisions.stage{i}, '2') +end + +function testExactHomologDominates_tc0098(testCase) + % EC tree 10 /s (ec4:3-5: bias 0.1, variance 1) and a homolog at 100% + % identity measured at 100 /s (exact: bias 0, variance 0.01): + % (0.9 * 1 + 2 * 100) / 101. geckopy's test_exact_homolog_dominates + % has the same numbers. + [model, adapter, rxns] = buildProject('ec_tree_homologs'); + tree = struct('source', 'ec_tree', 'rxns', {rxns(1)}, 'kcats', 10, 'detail', {{'n=4; depth=4'}}); + saveKcatSource(model, tree, 'ec_tree', 'modelAdapter', adapter); + hom = struct('source', 'homologs', 'rxns', {rxns(1)}, 'kcats', 100, 'substrates', {{'m1'}}, ... + 'detail', {{'identity=1.000; n=1'}}); + saveKcatSource(model, hom, 'homologs', 'modelAdapter', adapter); + decisions = collectKcats(model, 'modelAdapter', adapter, 'writeReport', false); + i = find(strcmp(decisions.ecRxn, rxns{1})); + verifyEqual(testCase, decisions.kcat(i), 10 ^ ((0.9 + 200) / 101), 'RelTol', 1e-12) +end + +function testCombineErrors_tc0090(testCase) + % An OKP method without combination parameters, and an unknown method. + [model, adapter, rxns] = buildProject('okp'); + adapter.params.kcat_sources.okp.methods = {'EITLEM'}; + saveKcatSource(model, okpList(rxns(1), 100, 30, 'EITLEM'), 'okp_eitlem', 'modelAdapter', adapter); + verifyError(testCase, @() collectKcats(model, 'modelAdapter', adapter, 'writeReport', false), ... + 'collectKcats:combine') + adapter.params.kcat_sources.okp.methods = {'CataPro', 'NoSuchMethod'}; + verifyError(testCase, @() kcatAssignmentConfig(adapter.params), 'kcatAssignment:config') +end + +function list = okpList(rxns, kcat, similarity, method) + n = numel(rxns); + list = struct('source', 'OpenKineticsPredictor', 'rxns', {rxns(:)}, 'kcats', repmat(kcat, n, 1), ... + 'kcatSource', {repmat({['OKP-' method]}, n, 1)}, ... + 'detail', {repmat({sprintf('similarity=%g', similarity)}, n, 1)}); +end + +function [model, adapter, rxns] = buildProject(preset) + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); + project = tempname; + copyfile(fullfile(adapter.params.path, 'data'), fullfile(project, 'data')); + delete(fullfile(project, 'data', 'customKcats.tsv')); + adapter.params.path = project; + adapter.params.kcat_assignment = struct('preset', preset); + adapter.params.kcat_sources = struct('okp', struct('methods', {{'CataPro', 'UniKP'}})); + % TestGEMAdapter's BRENDA folder is the project's data folder. + fid = fopen(fullfile(project, 'data', 'kcatCombineParams.tsv'), 'w'); + fprintf(fid, ['# Combination parameters for tests\n# measurement_sd: 0.5\n# min_variance: 0.01\n' ... + '# interval_scale ec_tree+okp: 2\n# interval_scale okp: 1\nsource\tbin\tbias\tvariance\tn\n' ... + 'ec_tree\tec4:3-5\t0.1\t1\t50\nec_tree\tec3\t0\t4\t50\nokp_catapro\t<40\t0.2\t2\t50\n' ... + 'okp_catapro\t>80\t0\t0.5\t50\nokp_unikp\t40-60\t-0.3\t1\t50\n' ... + 'homologs\t90\t0\t1\t50\nhomologs\texact\t0\t0.01\t0\n']); + fclose(fid); + model = makeEcModel(getGeckoTestModel(), false, adapter); + model = getECfromGEM(model); + rxns = model.ec.rxns(any(model.ec.rxnEnzMat, 2)); +end diff --git a/test/unit_tests/ecFromDatabaseConflictTests.m b/test/unit_tests/ecFromDatabaseConflictTests.m new file mode 100644 index 00000000..1eb6f414 --- /dev/null +++ b/test/unit_tests/ecFromDatabaseConflictTests.m @@ -0,0 +1,66 @@ +%run this test case with the command +%results = runtests('ecFromDatabaseConflictTests.m') + +function tests = ecFromDatabaseConflictTests + tests = functiontests(localfunctions); +end + +function testGetECfromDatabaseDisplayWarnsAndUsesFirst_tc0404(testCase) + [ecModel, adapter] = conflictModel(testCase); + verifyWarning(testCase, @() getECfromDatabase(ecModel, [], 'display', adapter), 'getECfromDatabase:conflicts') + ecModel2 = getECfromDatabase(ecModel, [], 'ignore', adapter); + verifyEqual(testCase, ecModel2.ec.eccodes, {'1.1.1.1';'1.1.1.1';'1.1.1.1';'1.1.1.1';'1.1.2.1';'1.1.1.3'}) + warning('off', 'getECfromDatabase:conflicts') + cleanup = onCleanup(@() warning('on', 'getECfromDatabase:conflicts')); %#ok + displayed = getECfromDatabase(ecModel, [], 'display', adapter); + verifyEqual(testCase, displayed.ec.eccodes, ecModel2.ec.eccodes) +end + +function testGetECfromDatabaseIgnoresConflictOutsideSelection_tc0405(testCase) + [ecModel, adapter] = conflictModel(testCase); + selected = strcmp(ecModel.ec.rxns, 'R2_EXP_1'); + lastwarn('') + ecModel2 = getECfromDatabase(ecModel, selected, 'display', adapter); + verifyEmpty(testCase, lastwarn()) + verifyEqual(testCase, ecModel2.ec.eccodes(selected), {'1.1.1.1'}) + verifyEqual(testCase, ecModel2.ec.eccodes(~selected), repmat({''}, nnz(~selected), 1)) +end + +function testGetECfromDatabaseEmptySelectionChangesNothing_tc0406(testCase) + % An empty logical selection searches nothing and returns the model as it + % is; [] selects every ec reaction. + [ecModel, adapter] = conflictModel(testCase); + ecModel.ec.eccodes = repmat({'9.9.9.9'}, numel(ecModel.ec.rxns), 1); + lastwarn('') + same = getECfromDatabase(ecModel, false(0,1), 'display', adapter); + verifyEqual(testCase, same, ecModel) + verifyEmpty(testCase, lastwarn()) + warning('off', 'getECfromDatabase:conflicts') + cleanup = onCleanup(@() warning('on', 'getECfromDatabase:conflicts')); %#ok + all = getECfromDatabase(ecModel, [], 'ignore', adapter); + verifyEqual(testCase, all.ec.eccodes{1}, '1.1.1.1') +end + +function testGetECfromDatabaseRejectsUnsupportedAction_tc0409(testCase) + [ecModel, adapter] = conflictModel(testCase); + verifyError(testCase, @() getECfromDatabase(ecModel, [], 'add', adapter), 'getECfromDatabase:unsupportedAction') + verifyError(testCase, @() getECfromDatabase(ecModel, [], 'other', adapter), 'getECfromDatabase:unsupportedAction') +end + +function [ecModel, adapter] = conflictModel(testCase) + % ecTestGEM with a second UniProt entry for gene G4 and another EC number. + geckoPath = findGECKOroot; + source = fullfile(geckoPath,'test','unit_tests','ecTestGEM'); + adapter = ModelAdapterManager.getAdapter(fullfile(source, 'TestGEMAdapter.m')); + model = getGeckoTestModel(); + ecModel = makeEcModel(model, false, adapter); + folder = tempname(); + mkdir(fullfile(folder, 'data')); + testCase.addTeardown(@() rmdir(folder, 's')) + copyfile(fullfile(source, 'data', 'uniprot.tsv'), fullfile(folder, 'data', 'uniprot.tsv')) + copyfile(fullfile(source, 'data', 'kegg.tsv'), fullfile(folder, 'data', 'kegg.tsv')) + fid = fopen(fullfile(folder, 'data', 'uniprot.tsv'), 'a'); + fprintf(fid, '\nP4b\tG4\t1.1.2.2\t40001\tMDFM\n'); + fclose(fid); + adapter.params.path = folder; +end diff --git a/test/unit_tests/ecModelBuildTests.m b/test/unit_tests/ecModelBuildTests.m new file mode 100644 index 00000000..523ecd7b --- /dev/null +++ b/test/unit_tests/ecModelBuildTests.m @@ -0,0 +1,206 @@ +%run this test case with the command +%results = runtests('ecModelBuildTests.m') + +function tests = ecModelBuildTests + tests = functiontests(localfunctions); +end + +function testLightNestedGeneRuleExpandsToIsozymes_tc0210(testCase) + % 'G1 and (G2 or G3)' is the two isozymes {G1,G2} and {G1,G3}; the + % brackets must not be dropped, which would make the second one {G3}. + adapter = getAdapter(); + model = getGeckoTestModel(); + model = changeGrRules(model, {'R2'}, {'G1 and (G2 or G3)'}, true); + ecModel = makeEcModel(model, true, adapter); + verifyEqual(testCase, sort(coupledGenes(ecModel, '001_R2')), {'G1';'G2'}) + verifyEqual(testCase, sort(coupledGenes(ecModel, '002_R2')), {'G1';'G3'}) + verifyEqual(testCase, sum(strcmp(ecModel.ec.rxns, '003_R2')), 0) +end + +function testAddNewRxnsToECNestedRuleAndGeneIdWithOr_tc0211(testCase) + % The gene ids of the rule are whole words, so 'orfX' is a gene and not + % the operator 'or' followed by 'fX', and the nested rule is split into + % one reaction per isozyme: 'orfX and GNEW2' and 'orfX and GNEW3'. + adapter = getAdapter(); + model = getGeckoTestModel(); + ecModel = makeEcModel(model, false, adapter); + + newRxns.rxns = {'RNEWA'}; + newRxns.rxnNames = {'RNEWA'}; + newRxns.equations = {'m1[c] => e2[e]'}; + newRxns.grRules = {'orfX and (GNEW2 or GNEW3)'}; + newEnzymes.enzymes = {'ENEW1';'ENEW2';'ENEW3'}; + newEnzymes.genes = {'orfX';'GNEW2';'GNEW3'}; + newEnzymes.mw = [15000;16000;17000]; + + ecModel = addNewRxnsToEC(ecModel, newRxns, newEnzymes, adapter); + verifyEqual(testCase, ecModel.grRules(strcmp(ecModel.rxns, 'RNEWA_EXP_1')), {'orfX and GNEW2'}) + verifyEqual(testCase, ecModel.grRules(strcmp(ecModel.rxns, 'RNEWA_EXP_2')), {'orfX and GNEW3'}) +end + +function testMakeEcModelCouplesTheKnownSubunitsOfAComplex_tc0212(testCase) + % GX is in neither database: the reaction is still coupled to the enzyme + % of G4, as the databases know it. + adapter = getAdapter(); + model = getGeckoTestModel(); + model = changeGrRules(model, {'R3'}, {'G4 and GX'}, true); + ecModel = makeEcModel(model, false, adapter); + verifyEqual(testCase, coupledGenes(ecModel, 'R3'), {'G4'}) +end + +function testMapRxnsToConvStripsOnlyTheSuffixes_tc0213(testCase) + % R_REVX is a conventional reaction whose id contains _REV; its reverse + % variant R_REVX_REV carries flux that maps back to it with the opposite sign. + adapter = getAdapter(); + model = getGeckoTestModel(); + model.rxns{strcmp(model.rxns, 'R1')} = 'R_REVX'; + ecModel = makeEcModel(model, false, adapter); + fluxVect = zeros(numel(ecModel.rxns), 1); + fluxVect(strcmp(ecModel.rxns, 'R_REVX')) = 5; + fluxVect(strcmp(ecModel.rxns, 'R_REVX_REV')) = 2; + mappedFlux = mapRxnsToConv(ecModel, model, fluxVect); + verifyEqual(testCase, mappedFlux(strcmp(model.rxns, 'R_REVX')), 3) +end + +function testEcFVAStripsOnlyTheSuffixes_tc0214(testCase) + % The same reaction id in ecFVA, which groups the variants of each + % conventional reaction by id. + adapter = getAdapter(); + model = getGeckoTestModel(); + model.rxns{strcmp(model.rxns, 'R1')} = 'R_REVX'; + ecModel = makeEcModel(model, false, adapter); + [minFlux, maxFlux] = ecFVA(ecModel, model, 'runParallel', false); + verifySize(testCase, minFlux, [numel(model.rxns) 1]) + verifySize(testCase, maxFlux, [numel(model.rxns) 1]) +end + +function testApplyKcatConstraintsLightSkipsIsozymeWithoutEnzymes_tc0215(testCase) + % R2 has two isozymes; the second one has no enzyme but a kcat. It cannot + % be the cheapest isozyme: the cost of R2 is the one of the first. + adapter = getAdapter(); + model = getGeckoTestModel(); + lecModel = makeEcModel(model, true, adapter); + lecModel.ec.kcat(:) = 10; + first = strcmp(lecModel.ec.rxns, '001_R2'); + second = strcmp(lecModel.ec.rxns, '002_R2'); + lecModel.ec.rxnEnzMat(second,:) = 0; + lecModel = applyKcatConstraints(lecModel); + expected = -(lecModel.ec.rxnEnzMat(first,:) * lecModel.ec.mw) / 10 / 3600; + actual = full(lecModel.S(strcmp(lecModel.mets, 'prot_pool'), strcmp(lecModel.rxns, 'R2'))); + verifyGreaterThan(testCase, abs(expected), 0) + verifyEqual(testCase, actual, expected, 'AbsTol', 1e-10) +end + + +function testAddNewRxnsToECGeneIdsContainingAnd_tc0232(testCase) + % Gene ids that contain 'and' (Sand1, andA, GandH) are whole words: the + % new reaction is coupled to exactly the enzymes of the genes in its rule. + adapter = getAdapter(); + model = getGeckoTestModel(); + ecModel = makeEcModel(model, false, adapter); + + newRxns.rxns = {'RNEWB'}; + newRxns.rxnNames = {'RNEWB'}; + newRxns.equations = {'m1[c] => e2[e]'}; + newRxns.grRules = {'Sand1 and (andA or GandH)'}; + newEnzymes.enzymes = {'ENEWA';'ENEWB';'ENEWC'}; + newEnzymes.genes = {'Sand1';'andA';'GandH'}; + newEnzymes.mw = [15000;16000;17000]; + + ecModel = addNewRxnsToEC(ecModel, newRxns, newEnzymes, adapter); + verifyEqual(testCase, sort(coupledGenes(ecModel, 'RNEWB_EXP_1')), {'Sand1';'andA'}) + verifyEqual(testCase, sort(coupledGenes(ecModel, 'RNEWB_EXP_2')), {'GandH';'Sand1'}) +end + +function testAddNewRxnsToECUpperCaseOperators_tc0237(testCase) + % 'AND' and 'OR' are operators like 'and' and 'or', also in a rule with a + % single clause and on a reversible reaction, where the rule is copied as + % it is to the reverse reaction. + adapter = getAdapter(); + model = getGeckoTestModel(); + ecModel = makeEcModel(model, false, adapter); + + newRxns.rxns = {'RNEWC';'RNEWD'}; + newRxns.rxnNames = {'RNEWC';'RNEWD'}; + newRxns.equations = {'m1[c] <=> e2[e]';'m1[c] => e2[e]'}; + newRxns.grRules = {'Sand1 AND andA';'Sand1 OR andA'}; + newEnzymes.enzymes = {'ENEWA';'ENEWB'}; + newEnzymes.genes = {'Sand1';'andA'}; + newEnzymes.mw = [15000;16000]; + + ecModel = addNewRxnsToEC(ecModel, newRxns, newEnzymes, adapter); + verifyEqual(testCase, ecModel.grRules(strcmp(ecModel.rxns, 'RNEWC')), {'Sand1 and andA'}) + verifyEqual(testCase, sort(coupledGenes(ecModel, 'RNEWC')), {'Sand1';'andA'}) + verifyEqual(testCase, sort(coupledGenes(ecModel, 'RNEWC_REV')), {'Sand1';'andA'}) + verifyEqual(testCase, coupledGenes(ecModel, 'RNEWD_EXP_1'), {'Sand1'}) + verifyEqual(testCase, coupledGenes(ecModel, 'RNEWD_EXP_2'), {'andA'}) +end + +function testLightGeneRuleOperatorsAreCaseInsensitive_tc0233(testCase) + % 'AND' and 'OR' are operators like 'and' and 'or'. + adapter = getAdapter(); + model = getGeckoTestModel(); + model.grRules{strcmp(model.rxns, 'R2')} = 'G1 AND (G2 OR G3)'; + ecModel = makeEcModel(model, true, adapter); + verifyEqual(testCase, sort(coupledGenes(ecModel, '001_R2')), {'G1';'G2'}) + verifyEqual(testCase, sort(coupledGenes(ecModel, '002_R2')), {'G1';'G3'}) +end + +function testLightReactionWithEmptyRuleKeepsOneRow_tc0234(testCase) + % A reaction that has gene entries but an empty gene rule keeps one row + % in ec.rxns, without enzymes. + adapter = getAdapter(); + model = getGeckoTestModel(); + model.grRules{strcmp(model.rxns, 'R2')} = ''; + ecModel = makeEcModel(model, true, adapter); + row = strcmp(ecModel.ec.rxns, '001_R2'); + verifyEqual(testCase, sum(row), 1) + verifyEmpty(testCase, coupledGenes(ecModel, '001_R2')) +end + +function testApplyKcatConstraintsLightSkipsNonPositiveKcat_tc0235(testCase) + % A negative kcat is not a usable kcat: the cost of R2 is the one of the + % isozyme with a positive kcat. + adapter = getAdapter(); + model = getGeckoTestModel(); + lecModel = makeEcModel(model, true, adapter); + lecModel.ec.kcat(:) = 10; + first = strcmp(lecModel.ec.rxns, '001_R2'); + second = strcmp(lecModel.ec.rxns, '002_R2'); + lecModel.ec.kcat(first) = -5; + lecModel = applyKcatConstraints(lecModel); + expected = -(lecModel.ec.rxnEnzMat(second,:) * lecModel.ec.mw) / 10 / 3600; + actual = full(lecModel.S(strcmp(lecModel.mets, 'prot_pool'), strcmp(lecModel.rxns, 'R2'))); + verifyGreaterThan(testCase, abs(expected), 0) + verifyEqual(testCase, actual, expected, 'AbsTol', 1e-10) +end + +function testApplyKcatConstraintsLightSkipsEnzymeWithoutMass_tc0238(testCase) + % An isozyme whose enzymes have no mass gives a cost of 0, which is not a + % usable cost: the cost of R2 is the one of the isozyme with a mass. + adapter = getAdapter(); + model = getGeckoTestModel(); + lecModel = makeEcModel(model, true, adapter); + lecModel.ec.kcat(:) = 10; + first = strcmp(lecModel.ec.rxns, '001_R2'); + second = strcmp(lecModel.ec.rxns, '002_R2'); + onlyFirst = find(full(lecModel.ec.rxnEnzMat(first,:)) > 0 & full(lecModel.ec.rxnEnzMat(second,:)) == 0); + verifyNotEmpty(testCase, onlyFirst) + lecModel.ec.mw(onlyFirst) = 0; + lecModel = applyKcatConstraints(lecModel); + expected = -full(lecModel.ec.rxnEnzMat(second,:) * lecModel.ec.mw) / 10 / 3600; + actual = full(lecModel.S(strcmp(lecModel.mets, 'prot_pool'), strcmp(lecModel.rxns, 'R2'))); + verifyGreaterThan(testCase, abs(expected), 0) + verifyEqual(testCase, actual, expected, 'AbsTol', 1e-10) +end + +function adapter = getAdapter() +geckoPath = findGECKOroot; +adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); +end + +function genes = coupledGenes(ecModel, ecRxn) +% The genes of the enzymes that ec reaction ecRxn is coupled to. +row = strcmp(ecModel.ec.rxns, ecRxn); +genes = ecModel.ec.genes(logical(ecModel.ec.rxnEnzMat(row,:))); +end diff --git a/test/unit_tests/ecTestGEM/data/homologFixture/enzymes.fasta b/test/unit_tests/ecTestGEM/data/homologFixture/enzymes.fasta new file mode 100644 index 00000000..0a9b4028 --- /dev/null +++ b/test/unit_tests/ecTestGEM/data/homologFixture/enzymes.fasta @@ -0,0 +1,4 @@ +>P4 +MHMDRTVEICYKKWGVTCIFEDWIYHVTDESADVEGDWCWCMVELEWCDRTISSTQTHASWHHAFTELPHCANNRHEWDYIFHTYDTNWHQTPGYRRHVKPSMDAIICTWVMFKPCSVPVQPTINEVRIFFEQHFGYCWCYPGKYYKYPKPMVWPHCWGWYMYLCTMCRHHFIWNPCFKKMLRCKVVAIFTYCCWDAYTKKFEPYPPYGFHVPGVFYFWARESCENTGENWLIETNERQASWHGKEYFLMYCGGAEPYCGKFVREGIPEATNHAALRAWRAFVRNGPAGLCRKPCPLDQL +>P5 +MKSYALFVKMFHQVIPWFYRHDSYVPYISQLFQTGIRMNLICAQPFPRGKNTTASHHFIKADENTAGMMVMIPAAAEIADFWKPMNIWRLGTHAHVWRWSPMTLHTFWHSYYFCGAAEIDQMANCTDYNGMRFRDDCAIIAHRKRMMCMEEIWPTSKTRPFSYNAEYLYWEAGIEFHRNLRLYHSRDVPHADERMTRADCDWFKTHQCRPSIVYRYVWEGKPPNGNGMHCCDHCFKCNNAQWWNRPADTGVIELSCRYRSMNWLYGDNEALCHQVYWQQKPGFFEPQWIDMLDGMYALYK diff --git a/test/unit_tests/ecTestGEM/data/homologFixture/measurements.tsv b/test/unit_tests/ecTestGEM/data/homologFixture/measurements.tsv new file mode 100644 index 00000000..20715614 --- /dev/null +++ b/test/unit_tests/ecTestGEM/data/homologFixture/measurements.tsv @@ -0,0 +1,7 @@ +# BRENDA release test - homolog fixture +ec substrate substrate_inchikey organism taxid uniprot seq_id kcat temperature ph pmid +1.1.2.1 m1 AAAAAAAAAAAAAA-BBBBBBBBSA Testus 1 Q1 h1 10 +1.1.2.1 m1 AAAAAAAAAAAAAA-BBBBBBBBSA Testus 1 Q1 h1 40 +1.1.2.1 m1 AAAAAAAAAAAAAA-BBBBBBBBSA Testus 1 Q2 h2 100 +1.1.2.1 m1 AAAAAAAAAAAAAA-BBBBBBBBSA Testus 1 Q3 h3 1000 +1.1.1.3 m3 CCCCCCCCCCCCCC-DDDDDDDDSA Testus 1 Q1 h1 5 diff --git a/test/unit_tests/ecTestGEM/data/homologFixture/sequences.fasta b/test/unit_tests/ecTestGEM/data/homologFixture/sequences.fasta new file mode 100644 index 00000000..a83e6c90 --- /dev/null +++ b/test/unit_tests/ecTestGEM/data/homologFixture/sequences.fasta @@ -0,0 +1,6 @@ +>h1 +MHMDRTVEICYKKWGVTCIFEDWIYHVTDESADVEGDWCWCMVELEWCDRTISSTQTHASWHHAFTELPHCANNRHEWDYIFHTYDTNWHQTPGYRRHVKPSMDAIICTWVMFKPCSVPVQPTINEVRIFFEQHFGYCWCYPGKYYKYPKPMVWPHCWGWYMYLCTMCRHHFIWNPCFKKMLRCKVVAIFTYCCWDAYTKKFEPYPPYGFHVPGVFYFWARESCENTGENWLIETNERQASWHGKEYFLMYCGGAEPYCGKFVREGIPEATNHAALRAWRAFVRNGPAGLCRKPCPLDQL +>h2 +MHMLRTVERCYKKGGVTCRFEDWRYHVTLESADFEGDWKWCMVMLEWCLRTISDTQTHISWHHIFTELYHCANWRHEWLYIFHEYDTNGHQTPPYRRHFKPSMLAIICEWVMFSPCSVYVQPTRNEVRRFFEQQFGYCGCYPGSYYKYYKPMVGPHCWPWYMYTCTMCCHHFIGNPCFSKMLRKKVVARFTYCKWDAYEKKFEYYPPYPFHVPPVFYFGARESKENTGMNWLIMTNERAASWHPKEYFTMYCGPAEPYKGKFVCEGIPMATNHIALRAGRAFVCNGPAPLCRKYCPLDAL +>h3 +MVASSDAYLVWRWCDWIQGPWFMTYCPCADSSRMSRYYSIKLEYNDGEFERPRDVMIRHAHLDMQNFGKGNFRDQREVGTSDAFNEDLFRAYYHEGGCIFISYAIDHHVICTMPGYSMSTGVLNCSSHIGPLLTPFVSTIVPLHVPQFIQCCRMGQQFRHYHDAYACEEYWQQVRDHPVTDKQCPVSGKVSWQWSKLKMRPELHKAPFEMFLWCAEGTLRFTQGAHPLPCQWKNVQKCNAFTWQQGCNVEMNVLCPGCMPLASSTCATKDHQSQYKPGYWFHPDWKTGNDNPPPWKFHCH diff --git a/test/unit_tests/ecTestGEM/data/homologFixture/substrates.tsv b/test/unit_tests/ecTestGEM/data/homologFixture/substrates.tsv new file mode 100644 index 00000000..56756e31 --- /dev/null +++ b/test/unit_tests/ecTestGEM/data/homologFixture/substrates.tsv @@ -0,0 +1,4 @@ +# substrates for the homolog fixture +inchikey kind value +AAAAAAAAAAAAAA-BBBBBBBBSA name m1 +EEEEEEEEEEEEEE-FFFFFFFFSA name m2 diff --git a/test/unit_tests/ecTestGEM/data/kcat.tsv b/test/unit_tests/ecTestGEM/data/kcat.tsv index d2b96bd1..818f6068 100644 --- a/test/unit_tests/ecTestGEM/data/kcat.tsv +++ b/test/unit_tests/ecTestGEM/data/kcat.tsv @@ -1,5 +1,5 @@ # BRENDA release test-fixture - kcat in 1/s ec_code substrate organism kcat_max kcat_median n references -1.1.1.1 m1 testus testus 1 1 1 * -1.1.1.1 m2 testus falsus 10 10 1 * -1.1.2.2 m1 testus testus 100 100 1 * +1.1.1.1 m1 testus testus 1 0.5 2 * +1.1.1.1 m2 testus falsus 10 4 2 * +1.1.2.2 m1 testus testus 100 40 2 * diff --git a/test/unit_tests/ecTestGEM/data/kcatSourceFixture.tsv b/test/unit_tests/ecTestGEM/data/kcatSourceFixture.tsv new file mode 100644 index 00000000..4cfdc9f1 --- /dev/null +++ b/test/unit_tests/ecTestGEM/data/kcatSourceFixture.tsv @@ -0,0 +1,16 @@ +# source: fixture +# generator: hand-written +"# parameters: {""aggregation"":""median""}" +# kind: curated + +rxn enzymes substrate kcat log10_sd source detail ec_code note +R2 P2 + P1 m1 12.5 0.3 brenda wc=0; origin=1 1.1.1.1 enzymes in another order +# a comment between rows +R3 P4 "2,3-bisphospho-D-glycerate" 1e-05 custom quoted substrate + +R5 P5 m2 5,5 custom decimal comma: invalid +R2_REV m2 7 custom reaction only + P3 3 custom enzymes only +R9 X1 -1 custom negative: invalid +R9 X1 4 custom unmatched + diff --git a/test/unit_tests/ecTreeTests.m b/test/unit_tests/ecTreeTests.m new file mode 100644 index 00000000..efe2e917 --- /dev/null +++ b/test/unit_tests/ecTreeTests.m @@ -0,0 +1,123 @@ +%run this test case with the command +%results = runtests('ecTreeTests.m') + +function tests = ecTreeTests + tests = functiontests(localfunctions); +end + +function testEcTreeWorkedExample_tc0084(testCase) + % log10 kcats: global median 2; class 1.1 median 1 (5 values), 1.1.1 + % median 1.5 (4 values). geckopy's test_ec_tree_worked_example has the + % same numbers. + m = table_(); + [v, n, depth, ec] = ecTreeEstimate({'1.1.1.1'}, m, 5); + % 1.1: 0.5*1 + 0.5*2 = 1.5; 1.1.1: 1.5; 1.1.1.1: 3/8*1 + 5/8*1.5. + verifyEqual(testCase, v, 1.3125, 'AbsTol', 1e-12) + verifyEqual(testCase, [n, depth], [3, 4]) + verifyEqual(testCase, ec, {'1.1.1.1'}) + [v, n, depth] = ecTreeEstimate({'1.1.1.9'; '1.1.1.-'}, m, 5); + verifyEqual(testCase, v, [1.5; 1.5], 'AbsTol', 1e-12) + verifyEqual(testCase, [n, depth], [0 3; 0 3]) + [~, ~, ~, ec] = ecTreeEstimate({'1.1.1.2; 1.1.1.1'; '1.1.1.9;1.1.1.8'}, m, 5); + verifyEqual(testCase, ec, {'1.1.1.1'; '1.1.1.9'}) + [v, ~, depth] = ecTreeEstimate({'9.9.9.9'; ''}, m, 5); + verifyEqual(testCase, depth, [0; 0]) + verifyEqual(testCase, v, [2; 2]) + verifyEqual(testCase, ecTreeEstimate({'1.1.1.1'}, m, 10), 403/273, 'AbsTol', 1e-12) + verifyError(testCase, @() ecTreeEstimate({'1.1.1.1'}, m, 0), 'ecTreeEstimate:k') +end + +function testBundledMeasurements_tc0085(testCase) + m = loadBrendaMeasurements('folder', fetchBrendaAsset()); + verifyTrue(testCase, startsWith(m.release, 'BRENDA release ')) + verifyGreaterThan(testCase, numel(m.ec), 50000) + verifyTrue(testCase, all(m.kcat > 0)) + verifyFalse(testCase, any(contains(m.ec, '-'))) + % A file that is not gzipped in the release, and a second call that + % reuses the downloads. + folder = fetchBrendaAsset({'kcatCombineParams.tsv'}); + verifyTrue(testCase, isfile(fullfile(folder, 'kcatCombineParams.tsv'))) + verifyEqual(testCase, fetchBrendaAsset(), folder) + verifyError(testCase, @() fetchBrendaAsset({'other.tsv'}), 'fetchBrendaAsset:file') +end + +function testKcatsFromECTreeWritesFile_tc0086(testCase) + [model, adapter, project] = buildProject(); + m = measurementsFor(model); + kcatList = kcatsFromECTree(model, 'measurements', m, 'modelAdapter', adapter); + withEc = model.ec.rxns(~cellfun(@isempty, model.ec.eccodes)); + verifyNotEmpty(testCase, withEc) + verifyEqual(testCase, sort(kcatList.rxns), sort(withEc)) + [~, i] = ismember(kcatList.rxns, model.ec.rxns); + verifyEqual(testCase, log10(kcatList.kcats), ecTreeEstimate(model.ec.eccodes(i), m, 5), 'AbsTol', 1e-12) + [~, loaded] = loadKcatSource(model, fullfile(project, 'data', 'kcats', 'ec_tree.tsv')); + records = loaded.records; + meta = loaded.header; + verifyEqual(testCase, meta.parameters, '{"k":5}') + verifyEqual(testCase, meta.data, 'BRENDA release test') + verifyEqual(testCase, unique(records.source), {'ec_tree'}) + verifyTrue(testCase, all(~cellfun(@isempty, regexp(records.detail, '^n=\d+; depth=[234]$', 'once')))) +end + +function testBrendaEcTreePreset_tc0087(testCase) + % The default preset: custom.tsv, then BRENDA at origin 1, then the EC + % tree; then the OKP methods combined. + [model, adapter, project] = buildProject(); + verifyFalse(testCase, isfield(adapter.params, 'kcat_assignment')) + writeMeasurements(fullfile(project, 'data', 'measurements.tsv'), measurementsFor(model)); + report = updateKcatSources(model, 'dryRun', true, 'modelAdapter', adapter); + verifyEqual(testCase, report.source(1:3)', {'custom','brenda','ec_tree'}) + verifyTrue(testCase, all(startsWith(report.source(4:end), 'okp_'))) + verifyEqual(testCase, report.status{3}, 'missing') + fuzzy = kcatsFromBrenda(model, 'aggregation', 'median', 'modelAdapter', adapter); + kcatsFromECTree(model, 'modelAdapter', adapter); + [decisions, rep] = collectKcats(model, 'modelAdapter', adapter, 'writeReport', false); + verifyEqual(testCase, rep.preset, 'brenda_ec_tree') + origin1 = fuzzy.rxns(fuzzy.origin == 1 & fuzzy.wildcardLvl == 0); + stage1 = strcmp(decisions.stage, '1'); + fromBrenda = stage1 & startsWith(decisions.source, 'brenda'); + verifyTrue(testCase, all(ismember(decisions.ecRxn(fromBrenda), origin1))) + verifyTrue(testCase, all(ismember(decisions.source(stage1 & ~fromBrenda), {'custom','ec_tree'}))) + verifyTrue(testCase, any(strcmp(decisions.source, 'ec_tree'))) + % Made from the adapter's measurement table with k = 5, as the preset + % asks: current. Another k makes it outdated. + report = updateKcatSources(model, 'dryRun', true, 'modelAdapter', adapter); + verifyEqual(testCase, report.status{3}, 'current') + kcatsFromECTree(model, 'k', 2, 'modelAdapter', adapter); + report = updateKcatSources(model, 'dryRun', true, 'modelAdapter', adapter); + verifyEqual(testCase, report.status{3}, 'outdated') +end + +function writeMeasurements(file, m) + fid = fopen(file, 'w'); + fprintf(fid, '# %s\nec\tkcat\n', m.release); + for i = 1:numel(m.ec) + fprintf(fid, '%s\t%.17g\n', m.ec{i}, m.kcat(i)); + end + fclose(fid); +end + +function m = table_() + ec = {'1.1.1.1'; '1.1.1.1'; '1.1.1.1'; '1.1.1.2'; '1.1.2.1'; '2.7.1.1'; '2.7.1.1'}; + m = struct('ec', {ec}, 'log10kcat', [0; 1; 2; 3; -1; 2; 2], 'release', 'BRENDA release test'); + m.kcat = 10 .^ m.log10kcat; +end + +function m = measurementsFor(model) + % Two measurements for each EC number of the model. + ecs = unique(strtrim(split(strjoin(model.ec.eccodes(~cellfun(@isempty, model.ec.eccodes)), ';'), ';'))); + ecs = ecs(~cellfun(@isempty, ecs)); + v = repelem((1:numel(ecs))', 2); + m = struct('ec', {repelem(ecs, 2)}, 'log10kcat', v, 'kcat', 10 .^ v, 'release', 'BRENDA release test'); +end + +function [base, adapter, project] = buildProject() + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); + project = tempname; + copyfile(fullfile(adapter.params.path, 'data'), fullfile(project, 'data')); + adapter.params.path = project; + model = getGeckoTestModel(); + base = makeEcModel(model, false, adapter); + base = getECfromGEM(base); +end diff --git a/test/unit_tests/geckoCoreFunctionTests.m b/test/unit_tests/geckoCoreFunctionTests.m index 4e8d1558..e133e721 100644 --- a/test/unit_tests/geckoCoreFunctionTests.m +++ b/test/unit_tests/geckoCoreFunctionTests.m @@ -184,6 +184,15 @@ function testgetECfromGEM_tc0006(testCase) ecModel2 = getECfromGEM(ecModel,ismember(ecModel.ec.rxns, {'001_R2';'001_R3'})); expEccodes = {'1.1.1.1';'';'1.1.2.1';'';'';''}; verifyEqual(testCase,ecModel2.ec.eccodes,expEccodes) + + %without a model.eccodes field: a warning and empty EC numbers + ecModel = makeEcModel(model, false, adapter); + ecModel = rmfield(ecModel,'eccodes'); + verifyWarning(testCase,@() getECfromGEM(ecModel),'getECfromGEM:noEccodes') + warning('off','getECfromGEM:noEccodes') + ecModel2 = getECfromGEM(ecModel); + warning('on','getECfromGEM:noEccodes') + verifyEqual(testCase,ecModel2.ec.eccodes,repmat({''},6,1)) end %For both full and light @@ -240,6 +249,9 @@ function testsaveECModel_tc0009(testCase) saveEcModel(ecModel, [], adapter); loadedEcModel = loadEcModel([],adapter); delete(fullfile(adapter.params.path,'models','ecModel.yml')); + verifyEqual(testCase, loadedEcModel.annotation.gecko_format, '4') + verifyTrue(testCase, startsWith(loadedEcModel.annotation.generator, 'GECKO ')) + loadedEcModel.annotation = rmfield(loadedEcModel.annotation, {'gecko_format', 'generator', 'note'}); verifyEqual(testCase, ecModel, loadedEcModel) % Test loading of conventional GEM @@ -249,6 +261,88 @@ function testsaveECModel_tc0009(testCase) verifyEqual(testCase, model, loadedModel) end +function testsaveECModelRxnWithoutEnzymes_tc0700(testCase) + % An ec reaction without enzymes is written without an enzymes entry; + % loadEcModel returns a zero row in rxnEnzMat for it and keeps its id, + % kcat and source. The two forms that earlier versions wrote for it, a + % content-less "enzymes: !!omap" and "enzymes: !!omap []", load the same. + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM', 'TestGEMAdapter.m')); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + k = find(full(sum(ecModel.ec.rxnEnzMat ~= 0, 2)) > 0, 1); + ecModel.ec.rxnEnzMat(k,:) = 0; + ecModel.ec.source{k} = 'standard'; + file = fullfile(adapter.params.path,'models','ecModel.yml'); + testCase.addTeardown(@() delete(file)); + saveEcModel(ecModel, [], adapter); + lines = strsplit(fileread(file), newline, 'CollapseDelimiters', false); + ecStart = find(strcmp(lines, '- ec-rxns:'), 1); + start = ecStart + find(strcmp(strtrim(lines(ecStart+1:end)), ['- id: ' ecModel.ec.rxns{k}]), 1); + verifyNotEmpty(testCase, start) + % the entry is followed by the next "- !!omap" or by the next section + stop = start + find(~startsWith(lines(start+1:end), ' '), 1); + entry = lines(start:stop-1); + verifyFalse(testCase, any(contains(entry, 'enzymes'))) + verifyTrue(testCase, any(contains(entry, 'source: standard'))) + verifyEqual(testCase, nnz(contains(lines, '!!omap []')), 0) + + forms = {' - enzymes: !!omap', ' - enzymes: !!omap []'}; + for i = 0:numel(forms) + if i > 0 + old = [lines(1:start), forms(i), lines(start+1:end)]; + fid = fopen(file, 'w'); + fprintf(fid, '%s', strjoin(old, newline)); + fclose(fid); + end + loaded = loadEcModel([], adapter); + verifyEqual(testCase, loaded.ec.rxns, ecModel.ec.rxns) + verifyEqual(testCase, loaded.ec.kcat, ecModel.ec.kcat, 'AbsTol', 1e-9) + verifyEqual(testCase, loaded.ec.source, ecModel.ec.source) + verifyEqual(testCase, full(loaded.ec.rxnEnzMat), full(ecModel.ec.rxnEnzMat)) + verifyTrue(testCase, all(loaded.ec.rxnEnzMat(k,:) == 0)) + end +end + +function testfuzzyKcatMatchingMedian_tc0060(testCase) + % Verifies that kcatAggregation selects which BRENDA aggregate is used. + % The fixture records a different median from the max for every triple, + % so a median run must return the median column throughout, while the + % matching itself -- which triple is chosen, at which wildcard level and + % origin -- is unchanged. + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM', 'TestGEMAdapter.m')); + model = getGeckoTestModel(); + ecModel = makeEcModel(model, false, adapter); + ecModel = getECfromGEM(ecModel); + + kcatListMax = fuzzyKcatMatching(ecModel, [], adapter); + verifyEqual(testCase, kcatListMax.kcats, [1;1;10;10;100;1]) + + kcatListMedian = fuzzyKcatMatching(ecModel, 'ecRxns', [], ... + 'modelAdapter', adapter, 'kcatAggregation', 'median'); + verifyEqual(testCase, kcatListMedian.kcats, [0.5;0.5;4;4;40;0.5]) + + % Only the values change; the matching does not. + verifyEqual(testCase, kcatListMedian.rxns, kcatListMax.rxns) + verifyEqual(testCase, kcatListMedian.eccodes, kcatListMax.eccodes) + verifyEqual(testCase, kcatListMedian.wildcardLvl, kcatListMax.wildcardLvl) + verifyEqual(testCase, kcatListMedian.origin, kcatListMax.origin) + + % 'max' is the default, and an unknown value is refused. + kcatListExplicitMax = fuzzyKcatMatching(ecModel, 'ecRxns', [], ... + 'modelAdapter', adapter, 'kcatAggregation', 'max'); + verifyEqual(testCase, kcatListExplicitMax.kcats, kcatListMax.kcats) + verifyError(testCase, @() fuzzyKcatMatching(ecModel, 'ecRxns', [], ... + 'modelAdapter', adapter, 'kcatAggregation', 'mean'), ... + 'fuzzyKcatMatching:invalidKcatAggregation') + + % Mixing positional and name-value arguments puts a name where a + % value belongs; that has to fail rather than quietly wildcard every + % EC number, which is what an unvalidated forceWClvl would do. + verifyError(testCase, @() fuzzyKcatMatching(ecModel, [], adapter, ... + 'kcatAggregation', 'median'), 'fuzzyKcatMatching:invalidForceWClvl') +end + function testfuzzyKcatMatching_tc0010(testCase) % Verifies fuzzyKcatMatching against ecTestGEM's fixture BRENDA data, for % both the full and light ecModel variants and for both the complete @@ -903,26 +997,19 @@ function testWriteOpenKineticsPredictorInputReactionSubsetIndex_tc0023(testCase) end -function testGetEnzymeBottlenecksRanksByShadowPrice_tc0024(testCase) - % Verifies getEnzymeBottlenecks solves the model, ranks enzymes by the - % absolute shadow price of their prot_ mass-balance constraint, and - % returns the top N rows. Checks the primal-derived columns (flux, - % capUsage, upperBound) exactly, that rows are sorted by non-increasing - % |shadowPrice|, and that 'top' limits the row count -- but not the exact - % shadow-price value for an enzyme carrying zero flux at the optimum, - % since that value is LP-dual-degenerate and can vary with the solver's - % platform/presolve path. - geckoPath = findGECKOroot; - adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM', 'TestGEMAdapter.m')); - model = getGeckoTestModel(); - model.lb(strcmp(model.rxns,'R2')) = 0; model.ub(strcmp(model.rxns,'R2')) = 0; - model.lb(strcmp(model.rxns,'R4')) = 0; model.ub(strcmp(model.rxns,'R4')) = 0; - ecModel = makeEcModel(model, false, adapter); - ecModel = getECfromGEM(ecModel); - ecModel.ec.kcat(:) = 10; - ecModel.ec.source(:) = {'manual'}; - ecModel = applyKcatConstraints(ecModel); - ecModel = setProtPoolSize(ecModel, 0.5, 0.5, 0.5, adapter); +function testGetEnzymeBottlenecksRanksByObjectiveGain_tc0024(testCase) + % Verifies getEnzymeBottlenecks solves the model and returns the top N + % rows with the columns objectiveGain, shadowPrice, flux, capUsage, + % upperBound and multipleActive. In this model no usage reaction runs at + % its upper bound and the protein pool is the only active constraint, so + % no enzyme is solved again, every objectiveGain is 0, the order is the + % order of model.ec.enzymes, and every row is marked multipleActive. + % Checks the primal-derived columns (flux, capUsage, upperBound) exactly, + % and that 'top' limits the row count -- but not the shadow-price value + % for an enzyme carrying zero flux at the optimum, since that value is + % LP-dual-degenerate and can vary with the solver's platform/presolve + % path. + ecModel = buildBottleneckTestModel(0.5); sol = solveLP(ecModel); verifyEqual(testCase, sol.stat, 1) @@ -930,21 +1017,196 @@ function testGetEnzymeBottlenecksRanksByShadowPrice_tc0024(testCase) bottlenecks = getEnzymeBottlenecks(ecModel); verifyEqual(testCase, height(bottlenecks), 5) + verifyEqual(testCase, bottlenecks.Properties.VariableNames, ... + {'uniprot','gene','objectiveGain','shadowPrice','flux','capUsage','upperBound','multipleActive'}) + + verifyEqual(testCase, bottlenecks.uniprot, {'P1';'P2';'P3';'P4';'P5'}) + verifyEqual(testCase, bottlenecks.objectiveGain, zeros(5, 1)) + verifyEqual(testCase, bottlenecks.flux, [0;0;0;55.555555555556;69.444444444444], 'AbsTol', 1e-9) + verifyEqual(testCase, bottlenecks.capUsage, [0;0;0;0.055555555555556;0.069444444444444], 'AbsTol', 1e-9) + verifyEqual(testCase, bottlenecks.upperBound, repmat(1000, 5, 1), 'AbsTol', 1e-9) + verifyTrue(testCase, all(bottlenecks.multipleActive)) + verifyEqual(testCase, bottlenecks.Properties.UserData.nResolved, 0) + verifyEqual(testCase, bottlenecks.Properties.UserData.activeConstraints, 1) - % Primal-derived values: unique regardless of dual degeneracy. - [~, order] = ismember({'P1','P2','P3','P4','P5'}, bottlenecks.uniprot); - verifyEqual(testCase, bottlenecks.flux(order), [0;0;0;55.555555555556;69.444444444444], 'AbsTol', 1e-9) - verifyEqual(testCase, bottlenecks.capUsage(order), [0;0;0;0.055555555555556;0.069444444444444], 'AbsTol', 1e-9) - verifyEqual(testCase, bottlenecks.upperBound(order), repmat(1000, 5, 1), 'AbsTol', 1e-9) - - % Sorted by non-increasing |shadow price| --- true whichever degenerate - % vertex the solver lands on. - verifyTrue(testCase, all(diff(abs(bottlenecks.shadowPrice)) <= 1e-9)) - - % top limits the row count to exactly what was asked for, whatever the - % tie-break among degenerate rows put there. top2 = getEnzymeBottlenecks(ecModel, 'top', 2); verifyEqual(testCase, height(top2), 2) + verifyEqual(testCase, top2.uniprot, {'P1';'P2'}) +end + + +function testGetEnzymeBottlenecksOrdersByResolvedGain_tc0277(testCase) + % Verifies that of two enzymes running at their upper bound, the one + % whose bound limits growth is ranked first with the growth gain of a + % solve with its bound doubled (positive for a maximised growth + % objective), and the one whose raised bound does not change growth (P3, + % whose usage is fixed by equal lower and upper bounds) has a gain of 0. + % Both enzymes are solved again, so nResolved is 2 and, with two active + % constraints, both rows are multipleActive. Only P5 and P3 are asserted + % as active; which of P1, P2 and P4 carry flux in the parallel routes is + % not unique. + ecModel = buildBottleneckTestModel(100, false); + ecModel.ub(strcmp(ecModel.rxns, 'usage_prot_P5')) = 20; + p3 = strcmp(ecModel.rxns, 'usage_prot_P3'); + ecModel.lb(p3) = 1; + ecModel.ub(p3) = 1; + + base = solveLP(ecModel); + verifyEqual(testCase, base.stat, 1) + raised = ecModel; + raised.ub(strcmp(raised.rxns, 'usage_prot_P5')) = 40; + expectedGain = solveLP(raised).f - base.f; + verifyGreaterThan(testCase, expectedGain, 1) + + bottlenecks = getEnzymeBottlenecks(ecModel); + verifyEqual(testCase, bottlenecks.uniprot{1}, 'P5') + verifyEqual(testCase, bottlenecks.objectiveGain(1), expectedGain, 'AbsTol', 1e-9) + verifyEqual(testCase, bottlenecks.objectiveGain(2:end), zeros(4, 1)) + row = strcmp(bottlenecks.uniprot, 'P3'); + verifyEqual(testCase, bottlenecks.capUsage(row), 1, 'AbsTol', 1e-9) + verifyTrue(testCase, all(bottlenecks.multipleActive(1) & bottlenecks.multipleActive(row))) + verifyEqual(testCase, bottlenecks.Properties.UserData.nResolved, 2) + verifyEqual(testCase, bottlenecks.Properties.UserData.activeConstraints, 2) + % rows with equal gain keep the order of model.ec.enzymes + verifyEqual(testCase, bottlenecks.uniprot(2:end), {'P1';'P2';'P3';'P4'}) +end + + +function testGetEnzymeBottlenecksRespectsFoldChange_tc0278(testCase) + % Verifies the foldChange argument sets the factor by which the upper + % bound of an enzyme at its bound is raised: the gain of P4 equals the + % growth change of a solve with its bound multiplied by 1.5, by 2 + % (default) and by 3, and the gain differs between factors. + ecModel = buildBottleneckTestModel(100); + ecModel.ub(strcmp(ecModel.rxns, 'usage_prot_P4')) = 16; + base = solveLP(ecModel).f; + + gains = zeros(1, 3); + factors = [1.5 2 3]; + for i = 1:3 + raised = ecModel; + raised.ub(strcmp(raised.rxns, 'usage_prot_P4')) = 16 * factors(i); + expected = solveLP(raised).f - base; + b = getEnzymeBottlenecks(ecModel, 'foldChange', factors(i)); + verifyEqual(testCase, b.uniprot{1}, 'P4') + verifyEqual(testCase, b.objectiveGain(1), expected, 'AbsTol', 1e-9) + gains(i) = b.objectiveGain(1); + end + verifyTrue(testCase, all(diff(gains) > 0)) + default = getEnzymeBottlenecks(ecModel); + verifyEqual(testCase, default.objectiveGain(1), gains(2), 'AbsTol', 1e-9) +end + + +function testGetEnzymeBottlenecksNonBindingEnzymeHasZeroGain_tc0279(testCase) + % Verifies an enzyme carrying flux below its upper bound is not solved + % again and has objectiveGain 0, while the one enzyme at its bound has a + % positive gain. nResolved is 1 and the protein pool is not active, so + % the enzyme at its bound is not multipleActive, while every other row + % is, because one constraint besides its own is active. + ecModel = buildBottleneckTestModel(100); + ecModel.ub(strcmp(ecModel.rxns, 'usage_prot_P4')) = 16; + ecModel.ub(strcmp(ecModel.rxns, 'usage_prot_P5')) = 40; + + bottlenecks = getEnzymeBottlenecks(ecModel); + verifyEqual(testCase, bottlenecks.uniprot{1}, 'P4') + verifyGreaterThan(testCase, bottlenecks.objectiveGain(1), 1) + verifyFalse(testCase, bottlenecks.multipleActive(1)) + row = strcmp(bottlenecks.uniprot, 'P5'); + verifyEqual(testCase, bottlenecks.flux(row), 20, 'AbsTol', 1e-9) + verifyEqual(testCase, bottlenecks.capUsage(row), 0.5, 'AbsTol', 1e-9) + verifyEqual(testCase, bottlenecks.objectiveGain(row), 0) + verifyTrue(testCase, bottlenecks.multipleActive(row)) + verifyEqual(testCase, bottlenecks.Properties.UserData.nResolved, 1) + verifyEqual(testCase, bottlenecks.Properties.UserData.activeConstraints, 1) +end + + +function testGetEnzymeBottlenecksErrorsWhenNotOptimal_tc0280(testCase) + % Verifies getEnzymeBottlenecks raises an error when the model cannot be + % solved to optimality (here: the growth reaction is forced above what + % the protein pool allows). + ecModel = buildBottleneckTestModel(0.5); + ecModel.lb(ecModel.c == 1) = 1000; + verifyNotEqual(testCase, solveLP(ecModel).stat, 1) + try + getEnzymeBottlenecks(ecModel); + message = ''; + catch err + message = err.message; + end + verifyTrue(testCase, startsWith(message, 'getEnzymeBottlenecks: solver status')) +end + + +function testGetEnzymeBottlenecksRejectsInvalidFoldChange_tc0281(testCase) + % Verifies foldChange values of 1, below 1, NaN and non-scalar raise + % getEnzymeBottlenecks:foldChange. + ecModel = buildBottleneckTestModel(100); + for value = {1, 0.5, 0, NaN, [2 3]} + verifyError(testCase, @() getEnzymeBottlenecks(ecModel, 'foldChange', value{1}), ... + 'getEnzymeBottlenecks:foldChange') + end +end + + +function testGetEnzymeBottlenecksWarnsWhenOnlyThePoolBinds_tc0282(testCase) + % Verifies that with every usage upper bound out of reach and a binding + % protein pool no enzyme is at its bound: the warning names the pool, + % nResolved is 0, every objectiveGain is 0 and the rows are in model order. + ecModel = buildBottleneckTestModel(100); + usageIdx = startsWith(ecModel.rxns, 'usage_prot_'); + ecModel.ub(usageIdx) = 1e6; + + lastwarn(''); + bottlenecks = verifyWarning(testCase, @() getEnzymeBottlenecks(ecModel), ... + 'getEnzymeBottlenecks:noEnzymeAtBound'); + verifyEqual(testCase, bottlenecks.Properties.UserData.nResolved, 0) + verifyEqual(testCase, bottlenecks.Properties.UserData.activeConstraints, 1) + verifyEqual(testCase, bottlenecks.objectiveGain, zeros(height(bottlenecks), 1)) + verifyEqual(testCase, bottlenecks.uniprot, ecModel.ec.enzymes(1:height(bottlenecks))) + verifyTrue(testCase, all(bottlenecks.multipleActive)) + verifyNotEmpty(testCase, strfind(lastwarn, 'the protein pool exchange is at its bound')) +end + + +function testGetEnzymeBottlenecksWarnsWhenNoConstraintIsActive_tc0283(testCase) + % Verifies that with the growth reaction R5 capped at 10 and the pool and + % usage bounds out of reach the warning says that no capacity constraint + % is active. + ecModel = buildBottleneckTestModel(1e6); + usageIdx = startsWith(ecModel.rxns, 'usage_prot_'); + ecModel.ub(usageIdx) = 1e6; + ecModel.ub(strcmp(ecModel.rxns, 'R5')) = 10; + + lastwarn(''); + bottlenecks = verifyWarning(testCase, @() getEnzymeBottlenecks(ecModel), ... + 'getEnzymeBottlenecks:noEnzymeAtBound'); + verifyEqual(testCase, bottlenecks.Properties.UserData.activeConstraints, 0) + verifyFalse(testCase, any(bottlenecks.multipleActive)) + verifyNotEmpty(testCase, strfind(lastwarn, 'no capacity constraint is active')) +end + + +function ecModel = buildBottleneckTestModel(poolSize, blockR2) + % Test model with kcat 10 for all enzymes, R4 blocked, R2 blocked unless + % blockR2 is false, and a protein pool of poolSize. + if nargin < 2 + blockR2 = true; + end + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM', 'TestGEMAdapter.m')); + model = getGeckoTestModel(); + if blockR2 + model.lb(strcmp(model.rxns,'R2')) = 0; model.ub(strcmp(model.rxns,'R2')) = 0; + end + model.lb(strcmp(model.rxns,'R4')) = 0; model.ub(strcmp(model.rxns,'R4')) = 0; + ecModel = makeEcModel(model, false, adapter); + ecModel = getECfromGEM(ecModel); + ecModel.ec.kcat(:) = 10; + ecModel.ec.source(:) = {'manual'}; + ecModel = applyKcatConstraints(ecModel); + ecModel = setProtPoolSize(ecModel, poolSize, 0.5, 0.5, adapter); end @@ -1002,6 +1264,34 @@ function testPfbaEnzymesMinimisesEnzymeUsage_tc0025(testCase) end +function testPfbaEnzymesFractionOfNegativeOptimum_tc0285(testCase) + % Verifies that 'fractionOfOptimum' below 1 lets a negative optimum fall + % by that fraction of its magnitude. The objective is -R5 with R5 >= 10, + % so its optimum is -10; at 0.9 the objective may fall to -11, and the + % solution stays feasible with R5 at its lower bound. + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM', 'TestGEMAdapter.m')); + model = getGeckoTestModel(); + ecModel = makeEcModel(model, false, adapter); + ecModel = getECfromGEM(ecModel); + ecModel.ec.kcat(:) = 10; + ecModel.ec.source(:) = {'manual'}; + ecModel = applyKcatConstraints(ecModel); + ecModel = setProtPoolSize(ecModel, 0.5, 0.5, 0.5, adapter); + ecModel = setParam(ecModel, 'lb', 'R5', 10); + ecModel = setParam(ecModel, 'obj', 'R5', -1); + + solution = getPfbaEnzymes(ecModel); + verifyEqual(testCase, solution.stat, 1) + verifyEqual(testCase, solution.objectiveValue, -10, 'RelTol', 1e-5) + + solution = getPfbaEnzymes(ecModel, 'fractionOfOptimum', 0.9); + verifyEqual(testCase, solution.stat, 1) + verifyEqual(testCase, solution.objectiveValue, -10, 'RelTol', 1e-5) + verifyGreaterThanOrEqual(testCase, solution.objectiveValue, -11) +end + + function ecModel = fixtureForRelaxProteomicsGreedy() % Builds the shared fixture used by the relaxProteomicsGreedy tests below: % ecTestGEM with uniform kcat=10 and protein pool sized via @@ -1123,6 +1413,35 @@ function testResolveOkpApiKeyResolutionOrder_tc0029(testCase) end +function testReadOpenKineticsPredictorCatRange_tc0069(testCase) + % CatRange's prediction is a class range ('10 to 100 s^-1'), read as its + % geometric midpoint, or half the upper bound for the class from 0. + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM', 'TestGEMAdapter.m')); + model = getGeckoTestModel(); + ecModel = makeEcModel(model, false, adapter); + ecModel = getECfromGEM(ecModel); + ecModel.metSmiles = repmat({''}, numel(ecModel.mets), 1); + ecModel.metSmiles(strcmp(ecModel.mets,'m1c')) = {'C(C1C)O'}; + + resultFile = [tempname '.csv']; + fid = fopen(resultFile,'w'); + fprintf(fid,'Predicted kcat range: kcat (1/s),Source kcat,Extra Info kcat,Protein Sequence,Substrate\n'); + fprintf(fid,'10 to 100 s^-1,Prediction from CatRange,Predicted range: 10 to 100 s^-1,MRAL,C(C1C)O\n'); + fclose(fid); + cleanupFile = onCleanup(@() delete(resultFile)); + kcatList = readOpenKineticsPredictorOutput(ecModel, 'outFile', resultFile, 'modelAdapter', adapter); + verifyEqual(testCase, kcatList.kcats, 10^1.5, 'RelTol', 1e-12) + verifyEqual(testCase, kcatList.kcatSource, {'OKP-CatRange'}) + + fid = fopen(resultFile,'w'); + fprintf(fid,'Predicted kcat range: kcat (1/s),Source kcat,Extra Info kcat,Protein Sequence,Substrate\n'); + fprintf(fid,'0 to 1e-08 s^-1,Prediction from CatRange,,MRAL,C(C1C)O\n'); + fclose(fid); + kcatList = readOpenKineticsPredictorOutput(ecModel, 'outFile', resultFile, 'modelAdapter', adapter); + verifyEqual(testCase, kcatList.kcats, 5e-9, 'RelTol', 1e-12) +end + function testFetchOpenKineticsPredictorUseStoredMatchesReader_tc0030(testCase) % Verifies fetchOpenKineticsPredictor's 'useStored' path (parsing an % already-downloaded result file, the only path testable without a live @@ -1198,28 +1517,26 @@ function testFindECInDBIntersectionDedupesWildcardPair_tc0032(testCase) function testFuzzyKcatMatchingWildcardExhaustionDoesNotCrash_tc0033(testCase) % Verifies that when an EC code has no BRENDA match at any wildcard - % level, including the fully wildcarded '-.-.-.-', fuzzyKcatMatching's - % escalation loop terminates cleanly and reports "no match" (kcat 0, - % origin NaN) instead of erroring. + % level, including the fully wildcarded '-.-.-.-' (which matches every + % EC number in BRENDA), fuzzyKcatMatching's escalation loop terminates + % cleanly and reports "no match" (kcat 0, origin NaN) instead of + % erroring. The fixture BRENDA kcat table has no rows, so nothing can match. geckoPath = findGECKOroot; adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM', 'TestGEMAdapter.m')); model = getGeckoTestModel(); ecModel = makeEcModel(model, false, adapter); ecModel = getECfromGEM(ecModel); - % An EC class unrelated, at every wildcard level, to anything in the - % fixture BRENDA file below. ecModel.ec.eccodes{strcmp(ecModel.ec.rxns, 'R2_EXP_1')} = '9.9.9.9'; scratchDir = fullfile(tempname); brendaDir = fullfile(scratchDir, 'data'); mkdir(brendaDir); cleanupDir = onCleanup(@() rmdir(scratchDir, 's')); - % Deliberately unrelated to '9.9.9.9' at every wildcard level, so the - % escalation loop runs out of levels without ever matching. + % No rows at all, so the escalation loop runs out of levels without + % ever matching. fid = fopen(fullfile(brendaDir, 'kcat.tsv'), 'w'); fprintf(fid, '# BRENDA release test-fixture - kcat in 1/s\n'); fprintf(fid, 'ec_code\tsubstrate\torganism\tkcat_max\tkcat_median\tn\treferences\n'); - fprintf(fid, '5.5.5.5\tm1\ttestus testus\t42\t42\t1\t*\n'); fclose(fid); fid = fopen(fullfile(brendaDir, 'mw.tsv'), 'w'); fprintf(fid, '# BRENDA release test-fixture - molecular weight in g/mol\n'); @@ -1352,7 +1669,7 @@ function testReadDLKcatOutputUnrecognizedSubstrateErrorsCleanly_tc0037(testCase) fclose(fid); try - readDLKcatOutput(ecModel, 'outFile', outFile, 'modelAdapter', adapter); + readDLKcatOutput(ecModel, 'outFile', outFile, 'modelAdapter', adapter, 'strict', true); errored = false; msg = ''; catch ME @@ -2120,3 +2437,91 @@ function testGECKOInstallerIsOlderVersion_tc0059(testCase) verifyFalse(testCase, older('4.0.0', '4.0.0b1')) verifyFalse(testCase, older('4.0.0b1', '4.0.0b2')) end + +function testGECKOInstallerIgnoresRavenPrerelease_tc0284(testCase) + % The pre-release suffix of the installed RAVEN is ignored when it is + % compared with the minimum RAVEN version. + older = @(ver, minVer) GECKOInstaller.isOlderVersion( ... + GECKOInstaller.releaseOf(ver), minVer); + verifyEqual(testCase, GECKOInstaller.releaseOf('3.0.0b2'), '3.0.0') + verifyEqual(testCase, GECKOInstaller.releaseOf('3.1'), '3.1.0') + verifyFalse(testCase, older('3.0.0b1', '3.0.0')) + verifyFalse(testCase, older('3.0.0b2', '3.0.0')) + verifyFalse(testCase, older('3.0.0', '3.0.0')) + verifyFalse(testCase, older('3.2.1', '3.0.0')) + verifyTrue(testCase, older('2.9.9', '3.0.0')) + verifyTrue(testCase, older('2.10.0b3', '3.0.0')) +end + +function testEcFSEOFSelectsTargetsByCorrelation_tc0100(testCase) + % Verifies ecFSEOF classifies a reaction as a target when the absolute + % flux correlates with the enforced production flux (default + % corrThreshold 0.9), as RAVEN's FSEOF does, and does not cut the list to + % the top quartile by slope. With R3 enforced, the flux of R5 falls as + % the shared enzyme pool goes to R3, and R3 itself follows the enforced + % flux; both are targets, the ones without a gene rule are not. + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM', 'TestGEMAdapter.m')); + model = getGeckoTestModel(); + model.geneShortNames = model.genes; + ecModel = makeEcModel(model, false, adapter); + ecModel = getECfromGEM(ecModel); + ecModel.ec.kcat(strcmp(ecModel.ec.rxns,'R2_EXP_1')) = 50; + ecModel.ec.kcat(strcmp(ecModel.ec.rxns,'R2_EXP_2')) = 10; + ecModel.ec.kcat(strcmp(ecModel.ec.rxns,'R2_REV_EXP_1')) = 50; + ecModel.ec.kcat(strcmp(ecModel.ec.rxns,'R2_REV_EXP_2')) = 10; + ecModel.ec.kcat(strcmp(ecModel.ec.rxns,'R3')) = 20; + ecModel.ec.kcat(strcmp(ecModel.ec.rxns,'R5')) = 100; + ecModel.ec.source(:) = {'manual'}; + ecModel = applyKcatConstraints(ecModel); + ecModel = setProtPoolSize(ecModel, [], [], [], adapter); + adapter.params.bioRxn = 'R5'; + + fseof = ecFSEOF(ecModel, 'R3', 'S1', 'nSteps', 6, 'modelAdapter', adapter); + targets = sort([fseof.rxnTargets(:,1); fseof.transportTargets(:,1)]); + verifyEqual(testCase, targets, {'R3';'R5'}) + verifyEqual(testCase, numel(fseof.alpha), 6) + + % The slope column is the absolute regression slope, highest score first + verifyTrue(testCase, all(cell2mat(fseof.rxnTargets(:,3)) > 0)) + + % The default corrThreshold is 0.9 + sameAsDefault = ecFSEOF(ecModel, 'R3', 'S1', 'nSteps', 6, 'modelAdapter', adapter, 'corrThreshold', 0.9); + verifyEqual(testCase, sameAsDefault.rxnTargets, fseof.rxnTargets) + + % The correlation of a reaction cannot exceed 1: a threshold above 1 gives no targets + none = ecFSEOF(ecModel, 'R3', 'S1', 'nSteps', 6, 'modelAdapter', adapter, 'corrThreshold', 1.5); + verifyEmpty(testCase, none.rxnTargets) + verifyEmpty(testCase, none.transportTargets) + verifyEmpty(testCase, none.geneTargets) +end + +function testEcFSEOFGeneTargetsComeFromReportedReactions_tc0236(testCase) + % The usage reactions of the enzymes are not reported, and they do not enter + % the gene targets either: the slope of a gene whose rule is the only gene of + % a reported reaction is the slope of that reaction. + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM', 'TestGEMAdapter.m')); + model = getGeckoTestModel(); + model.geneShortNames = model.genes; + ecModel = makeEcModel(model, false, adapter); + ecModel = getECfromGEM(ecModel); + ecModel.ec.kcat(strcmp(ecModel.ec.rxns,'R2_EXP_1')) = 50; + ecModel.ec.kcat(strcmp(ecModel.ec.rxns,'R2_EXP_2')) = 10; + ecModel.ec.kcat(strcmp(ecModel.ec.rxns,'R2_REV_EXP_1')) = 50; + ecModel.ec.kcat(strcmp(ecModel.ec.rxns,'R2_REV_EXP_2')) = 10; + ecModel.ec.kcat(strcmp(ecModel.ec.rxns,'R3')) = 20; + ecModel.ec.kcat(strcmp(ecModel.ec.rxns,'R5')) = 100; + ecModel.ec.source(:) = {'manual'}; + ecModel = applyKcatConstraints(ecModel); + ecModel = setProtPoolSize(ecModel, [], [], [], adapter); + adapter.params.bioRxn = 'R5'; + + fseof = ecFSEOF(ecModel, 'R3', 'S1', 'nSteps', 6, 'modelAdapter', adapter); + verifyNotEmpty(testCase, fseof.geneTargets) + for i = 1:size(fseof.geneTargets,1) + rxnRow = strcmp(fseof.rxnTargets(:,4), fseof.geneTargets{i,1}); + verifyEqual(testCase, sum(rxnRow), 1) + verifyEqual(testCase, fseof.geneTargets{i,3}, fseof.rxnTargets{rxnRow,3}, 'AbsTol', 1e-9) + end +end diff --git a/test/unit_tests/homologsTests.m b/test/unit_tests/homologsTests.m new file mode 100644 index 00000000..e9342aed --- /dev/null +++ b/test/unit_tests/homologsTests.m @@ -0,0 +1,84 @@ +%run this test case with the command +%results = runtests('homologsTests.m') + +function tests = homologsTests + tests = functiontests(localfunctions); +end + +% P4 (reaction R3, substrate m1) has an exact copy h1, measured on m1 at 10 +% and 40 /s, a copy h2 with 60 of 300 residues changed (80% identity), +% measured at 100 /s, and an unrelated h3 at 1000 /s. geckopy's +% test_homologs uses the same fixture (ecTestGEM/data/homologFixture). + +function testKcatsFromHomologs_tc0095(testCase) + [model, adapter, project] = buildProject(); + kcatList = kcatsFromHomologs(model, 'modelAdapter', adapter); + verifyEqual(testCase, kcatList.rxns, {'R3'}) + % h1 is the same protein (100% identity): its median alone, 20 /s. + verifyEqual(testCase, kcatList.kcats, 20, 'RelTol', 1e-12) + verifyEqual(testCase, kcatList.detail, {'identity=1.000; n=1'}) + verifyEqual(testCase, kcatList.substrates, {'m1'}) + [~, loaded] = loadKcatSource(model, fullfile(project, 'data', 'kcats', 'homologs.tsv')); + verifyEqual(testCase, loaded.header.parameters, '{"coverage":0.8,"k":10,"min_identity":0.4}') + verifyEqual(testCase, loaded.header.data, 'BRENDA release test') + verifyEqual(testCase, loaded.records.rxn, {'R3'}) + % Without h1, the homologs below 95% identity are averaged by identity: + % h2 (80%) alone. + seqs = fullfile(project, 'data', 'sequences.fasta'); + lines = strsplit(strtrim(fileread(seqs)), newline); + keep = ~ismember(1:numel(lines), [1 2]); % the >h1 header and its sequence + fid = fopen(seqs, 'w'); fprintf(fid, '%s\n', lines{keep}); fclose(fid); + rest = kcatsFromHomologs(model, 'save', false, 'modelAdapter', adapter); + verifyEqual(testCase, rest.kcats, 100, 'RelTol', 1e-12) + verifyEqual(testCase, rest.detail, {'identity=0.800; n=1'}) + % Above 90% identity nothing is left. + high = kcatsFromHomologs(model, 'minIdentity', 0.9, 'save', false, 'modelAdapter', adapter); + verifyEmpty(testCase, high.rxns) +end + +function testSubstrateMatching_tc0096(testCase) + % ChEBI and MetaNetX annotations first, then the name; geckopy's + % test_metabolite_inchikeys has the same case. + [model, adapter, project] = buildProject(); + fid = fopen(fullfile(project, 'data', 'substrates.tsv'), 'w'); + fprintf(fid, 'inchikey\tkind\tvalue\nAAAAAAAAAAAAAA-BBBBBBBBSA\tchebi\t12345\n'); + fclose(fid); + i = find(strcmp(model.mets, 'm1c')); + model.metNames{i} = 'not m1'; + model.metMiriams{i} = struct('name', {{'chebi'}}, 'value', {{'CHEBI:12345'}}); + kcatList = kcatsFromHomologs(model, 'save', false, 'modelAdapter', adapter); + verifyEqual(testCase, kcatList.rxns, {'R3'}) + pairs = extractEnzymeSubstratePairs(model, 'modelAdapter', adapter); + verifyTrue(testCase, any(model.ec.rxns(pairs.ecRxn) == "R3" & pairs.met == i)) +end + +function testHomologPresets_tc0097(testCase) + [~, adapter] = buildProject(); + adapter.params.kcat_assignment = struct('preset', 'ec_tree_homologs'); + config = kcatAssignmentConfig(adapter.params); + verifyEqual(testCase, {config.stages.action}, {'select', 'combine', 'combine'}) + verifyEqual(testCase, config.stages(2).files, {'ec_tree', 'homologs'}) + adapter.params.kcat_assignment = struct('preset', 'ec_tree_okp'); + config = kcatAssignmentConfig(adapter.params); + verifyEqual(testCase, config.stages(2).files(1:2), {'ec_tree', 'homologs'}) +end + +function [model, adapter, project] = buildProject() + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); + project = tempname; + copyfile(fullfile(adapter.params.path, 'data'), fullfile(project, 'data')); + % TestGEMAdapter's BRENDA folder is the project's data folder. + fixture = fullfile(geckoPath,'test','unit_tests','ecTestGEM','data','homologFixture'); + for f = {'measurements.tsv', 'sequences.fasta', 'substrates.tsv'} + copyfile(fullfile(fixture, f{1}), fullfile(project, 'data', f{1})); + end + adapter.params.path = project; + model = makeEcModel(getGeckoTestModel(), false, adapter); + model = getECfromGEM(model); + lines = strsplit(strtrim(fileread(fullfile(fixture, 'enzymes.fasta'))), newline); + for k = 1:2:numel(lines) + hit = strcmp(model.ec.enzymes, lines{k}(2:end)); + model.ec.sequence(hit) = lines(k+1); + end +end diff --git a/test/unit_tests/kcatAssignmentTests.m b/test/unit_tests/kcatAssignmentTests.m new file mode 100644 index 00000000..97cdae66 --- /dev/null +++ b/test/unit_tests/kcatAssignmentTests.m @@ -0,0 +1,153 @@ +%run this test case with the command +%results = runtests('kcatAssignmentTests.m') + +function tests = kcatAssignmentTests + tests = functiontests(localfunctions); +end + +function testAssignKcatsReproducesChain_tc0079(testCase) + % The gecko_classic preset gives the same model as the steps it + % replaces: fuzzyKcatMatching, readDLKcatOutput, mergeKcats, + % assignKcatValues, applyCustomKcats, getKcatAcrossIsozymes, + % getStandardKcat and applyKcatConstraints. + [base, adapter, project] = buildProject(); + adapter.params.kcat_assignment = struct('preset', 'gecko_classic'); + fuzzy = fuzzyKcatMatching(base, [], adapter); + dlkcat = readDLKcatOutput(base, 'modelAdapter', adapter); + % gecko_classic ranks the specific-activity matches (origin 5 and 6) above DLKcat + merged = mergeKcats({fuzzy, dlkcat}, {'database_top','dlkcat','database_bottom'}, 'topOriginLimit', 6); + A = assignKcatValues(base, merged); + A = applyCustomKcats(A, 'modelAdapter', adapter); + A = getKcatAcrossIsozymes(A); + A = getStandardKcat(A, 'modelAdapter', adapter); + A = applyKcatConstraints(A); + + kcatsFromBrenda(base, 'modelAdapter', adapter); + kcatsFromDLKcat(base, 'modelAdapter', adapter); + [B, decisions, report] = assignKcats(base, 'modelAdapter', adapter); + verifyEqual(testCase, B.ec.rxns, A.ec.rxns) + verifyEqual(testCase, B.ec.kcat, A.ec.kcat) + verifyEqual(testCase, B.ec.source, A.ec.source) + verifyEqual(testCase, B.S, A.S) + verifyEqual(testCase, report.preset, 'gecko_classic') + verifyEqual(testCase, decisions.ecRxn, B.ec.rxns) + verifyTrue(testCase, isfile(fullfile(project, 'output', [char(base.id) '_kcatDecisions.tsv']))) +end + +function testCollectKcatsLeavesModel_tc0080(testCase) + % collectKcats decides without changing the model; a missing source is + % reported; custom.tsv decides first. + [base, adapter, project] = buildProject(); + adapter.params.kcat_assignment = struct('preset', 'gecko_median'); + kcatsFromBrenda(base, 'modelAdapter', adapter); + [decisions, report, decided] = collectKcats(base, 'modelAdapter', adapter, 'writeReport', false); + verifyEqual(testCase, base.ec.kcat, zeros(numel(base.ec.rxns), 1)) + verifyEqual(testCase, report.missing, {'dlkcat'}) + verifyTrue(testCase, any(decided.ec.kcat > 0)) + + [baseRxns, enz] = getEcRxnKeys(base); + i = find(strcmp(base.ec.rxns, 'R3')); + writeLines(fullfile(project, 'data', 'kcats', 'custom.tsv'), {'# source: custom', '# kind: curated', ... + 'rxn enzymes kcat source', sprintf('%s %s 777 custom', baseRxns{i}, enz{i})}); + decisions = collectKcats(base, 'modelAdapter', adapter, 'writeReport', false); + verifyEqual(testCase, decisions.kcat(i), 777) + verifyEqual(testCase, decisions.source{i}, 'custom') + verifyEqual(testCase, decisions.stage{i}, '1') +end + +function testStagesFromToml_tc0081(testCase) + % Stages from model_adapter.toml, and their errors. + [base, adapter, project] = buildProject(); + kcatsFromBrenda(base, 'modelAdapter', adapter); + kcatsFromDLKcat(base, 'modelAdapter', adapter); + adapter.params.kcat_assignment = struct('stage', struct('action', 'select', ... + 'sources', {{'dlkcat'}}, 'criteria', 'min'), 'isozymes', false, 'standard', false); + decisions = collectKcats(base, 'modelAdapter', adapter, 'writeReport', false); + verifyEqual(testCase, unique(decisions.source(decisions.kcat > 0)), {'dlkcat'}) + verifyEqual(testCase, decisions.kcat(strcmp(decisions.ecRxn, 'R2_EXP_1')), 6.5) + adapter.params.kcat_assignment.preset = 'gecko_median'; + verifyError(testCase, @() collectKcats(base, 'modelAdapter', adapter), 'kcatAssignment:config') + adapter.params.kcat_assignment = struct('preset', 'gecko_fast'); + verifyError(testCase, @() collectKcats(base, 'modelAdapter', adapter), 'kcatAssignment:config') + + % The same stages read from a TOML file. + toml = fullfile(project, 'model_adapter.toml'); + writeLines(toml, {'conv_gem = "models/testModel.xml"', 'org_name = "testus testus"', ... + '[kcat_assignment]', 'isozymes = false', '[[kcat_assignment.stage]]', 'sources = ["dlkcat"]', ... + 'criteria = "min"', '[kcat_sources.brenda]', 'aggregation = "median"'}); + params = loadAdapterParams(toml); + verifyEqual(testCase, params.kcat_assignment.stage.sources, {'dlkcat'}) + verifyEqual(testCase, params.kcat_assignment.standard, true) + verifyEqual(testCase, params.kcat_sources.brenda.aggregation, 'median') +end + +function testUpdateKcatSources_tc0082(testCase) + % Missing and outdated sources are gathered; current ones are not. + [base, adapter, project] = buildProject(); + adapter.params.kcat_assignment = struct('preset', 'gecko_median'); + report = updateKcatSources(base, 'dryRun', true, 'modelAdapter', adapter); + verifyEqual(testCase, report.source', {'custom','brenda','dlkcat'}) + verifyEqual(testCase, report.status', {'skipped','missing','missing'}) + verifyFalse(testCase, isfolder(fullfile(project, 'data', 'kcats'))) + report = updateKcatSources(base, 'modelAdapter', adapter); + verifyEqual(testCase, report.status', {'skipped','gathered','gathered'}) + [~, loaded] = loadKcatSource(base, fullfile(project, 'data', 'kcats', 'brenda.tsv')); + meta = loaded.header; + verifyEqual(testCase, meta.parameters, '{"aggregation":"median","force_wildcard_level":0}') + report = updateKcatSources(base, 'modelAdapter', adapter); + verifyEqual(testCase, report.status', {'skipped','current','current'}) + % gecko_classic asks for the BRENDA maximum: brenda.tsv is outdated. + adapter.params.kcat_assignment = struct('preset', 'gecko_classic'); + report = updateKcatSources(base, 'dryRun', true, 'modelAdapter', adapter); + verifyEqual(testCase, report.status{2}, 'outdated') +end + +function testGeckoMedianPreset_tc0083(testCase) + % gecko_median: the BRENDA median, and BRENDA matches beyond origin 4 + % rank below DLKcat. + [base, adapter] = buildProject(); + adapter.params.kcat_assignment = struct('preset', 'gecko_median'); + fuzzy = kcatsFromBrenda(base, 'aggregation', 'median', 'modelAdapter', adapter); + dlkcat = kcatsFromDLKcat(base, 'modelAdapter', adapter); + merged = mergeKcats({fuzzy, dlkcat}, {'database_top','dlkcat','database_bottom'}, 'topOriginLimit', 4); + A = assignKcatValues(base, merged); + A = applyCustomKcats(A, 'modelAdapter', adapter); + A = getKcatAcrossIsozymes(A); + A = getStandardKcat(A, 'modelAdapter', adapter); + A = applyKcatConstraints(A); + [B, ~, report] = assignKcats(base, 'modelAdapter', adapter, 'writeReport', false); + verifyEqual(testCase, report.preset, 'gecko_median') + verifyEqual(testCase, B.ec.kcat, A.ec.kcat) + verifyEqual(testCase, B.ec.source, A.ec.source) + verifyEqual(testCase, B.S, A.S) +end + +function [base, adapter, project] = buildProject() + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); + project = tempname; + copyfile(fullfile(adapter.params.path, 'data'), fullfile(project, 'data')); + adapter.params.path = project; + model = getGeckoTestModel(); + base = makeEcModel(model, false, adapter); + base = getECfromGEM(base); + % DLKcat output for this model. + rows = {'R2_EXP_1','G1','m1','C','MRAL','12.5'; 'R2_EXP_1','G2','m1','C','MNTD','6.5'; ... + 'R3','G4','m1','C','MDFM','3.25'}; + fid = fopen(fullfile(project, 'data', 'DLKcat.tsv'), 'w'); + fprintf(fid, 'rxns\tgenes\tsubstrates\tsmiles\tsequence\tkcat\n'); + for i = 1:size(rows, 1) + fprintf(fid, '%s\t%s\t%s\t%s\t%s\t%s\n', rows{i,:}); + end + fclose(fid); +end + +function writeLines(file, lines) +folder = fileparts(file); +if ~isfolder(folder) + mkdir(folder); +end +fid = fopen(file, 'w'); +fprintf(fid, '%s\n', lines{:}); +fclose(fid); +end diff --git a/test/unit_tests/kcatContractTests.m b/test/unit_tests/kcatContractTests.m new file mode 100644 index 00000000..1539fe32 --- /dev/null +++ b/test/unit_tests/kcatContractTests.m @@ -0,0 +1,243 @@ +%run this test case with the command +%results = runtests('kcatContractTests.m') + +function tests = kcatContractTests + tests = functiontests(localfunctions); +end + +function testCollectKcatsCountsEachSourceFileOnce_tc0300(testCase) + % database_top and database_bottom both read brenda.tsv, which has an + % empty log10_sd (NaN) column: the file is one list, so R3 has the two + % values of the file as candidates, not four. + [model, adapter, project] = kcatProject(); + adapter.params.kcat_assignment = struct('isozymes', false, 'standard', false, 'stage', ... + struct('action', 'select', 'sources', {{'database_top', 'database_bottom'}})); + [baseRxns, enz] = getEcRxnKeys(model); + i = find(strcmp(model.ec.rxns, 'R3')); + writeLines(fullfile(project, 'data', 'kcats', 'brenda.tsv'), {'# source: brenda', ... + sprintf('rxn\tenzymes\tsubstrate\tkcat\tlog10_sd\tsource\tdetail'), ... + sprintf('%s\t%s\tm1\t5\t\tbrenda\twc=0; origin=1', baseRxns{i}, enz{i}), ... + sprintf('%s\t%s\tm1\t20\t\tbrenda\twc=0; origin=1', baseRxns{i}, enz{i})}); + decisions = collectKcats(model, 'modelAdapter', adapter, 'writeReport', false); + row = strcmp(decisions.ecRxn, 'R3'); + verifyEqual(testCase, decisions.kcat(row), 20) + verifyEqual(testCase, decisions.candidates(row), 2) + verifyEqual(testCase, decisions.spreadLog10(row), log10(4), 'AbsTol', 1e-12) +end + +function testMergeKcatsMatchesOkpTaggedSources_tc0301(testCase) + % The OKP- tag is dropped for matching: OKP-BRENDA is an exact database + % hit and OKP-CataPro matches the priority entry catapro; the rows keep + % their labels and win over DLKcat. + list = struct('source', 'x', 'rxns', {{'A'; 'A'; 'B'; 'B'}}, 'kcats', [3; 9; 4; 9], ... + 'kcatSource', {{'OKP-BRENDA'; 'DLKcat'; 'OKP-CataPro'; 'DLKcat'}}); + merged = mergeKcats({list}, {'database_exact', 'catapro', 'dlkcat'}); + verifyEqual(testCase, merged.rxns, {'A'; 'B'}) + verifyEqual(testCase, merged.kcats, [3; 4]) + verifyEqual(testCase, merged.kcatSource, {'OKP-BRENDA'; 'OKP-CataPro'}) +end + +function testLoadKcatSourceQuotedRows_tc0302(testCase) + % A row of empty quoted fields is blank and a quoted comment is a + % comment; a field that opens a quote and does not close it is an error. + [model, ~, project] = kcatProject(); + file = fullfile(project, 'odd.tsv'); + writeLines(file, {'# source: odd', sprintf('rxn\tenzymes\tkcat\tsource'), ... + sprintf('R3\tP4\t25\todd'), '"# a quoted comment"', sprintf('""\t""\t""\t""'), ... + sprintf('R5\tP5\t30\todd')}); + [list, report] = loadKcatSource(model, file); + verifyEqual(testCase, numel(report.records.kcat), 2) + verifyEmpty(testCase, report.invalid) + writeLines(file, {'# source: odd', sprintf('rxn\tenzymes\tkcat\tsource'), ... + sprintf('R3\tP4\t25\todd'), '"# a comment that was quoted'}); + verifyError(testCase, @() loadKcatSource(model, file), 'loadKcatSource:quote') + writeLines(file, {'# source: odd', sprintf('rxn\tenzymes\tkcat\tsource'), ... + sprintf('"R3\tP4\t25\todd')}); + verifyError(testCase, @() loadKcatSource(model, file), 'loadKcatSource:quote') +end + +function testReadDLKcatOutputKcatFields_tc0303(testCase) + % A kcat field that is not a finite number ('inf', '1.2.3', 'NA', 'None') + % drops the row before the reactions are checked; a file without a + % number raises. + [model, adapter, project] = kcatProject(); + file = fullfile(project, 'DLKcat_out.tsv'); + head = sprintf('rxns\tgenes\tsubstrates\tsmiles\tsequence\tkcat'); + row = @(r, s, k) sprintf('%s\tG1\t%s\tsmiles\tseq\t%s', r, s, k); + read = @() readDLKcatOutput(model, 'outFile', file, 'modelAdapter', adapter); + + writeLines(file, {head, row('R2_EXP_1', 'm1', '12.5'), row('R2_EXP_2', 'm1', 'inf'), ... + row('R2_EXP_2', 'm1', '1.2.3')}); + kcatList = read(); + verifyEqual(testCase, kcatList.rxns, {'R2_EXP_1'}) + verifyEqual(testCase, kcatList.kcats, 12.5) + + writeLines(file, {head, row('R2_EXP_1', 'm1', 'None'), row('R2_EXP_2', 'm1', 'None')}); + verifyError(testCase, read, 'readDLKcatOutput:noKcats') + + writeLines(file, {head, row('R2_EXP_1', 'm1', '12.5'), row('NOTAREACTION_EXP_1', 'm1', 'NA')}); + kcatList = read(); + verifyEqual(testCase, kcatList.rxns, {'R2_EXP_1'}) + + writeLines(file, {head, row('R2_EXP_1', 'm1', '12.5'), row('NOTAREACTION_EXP_1', 'm1', '7')}); + verifyError(testCase, read, 'readDLKcatOutput:unknownReaction') +end + +function testReadDLKcatOutputUnknownSubstrate_tc0304(testCase) + % A row with a substrate that is not in the model is left out with a + % warning; strict raises. + [model, adapter, project] = kcatProject(); + file = fullfile(project, 'DLKcat_out.tsv'); + writeLines(file, {sprintf('rxns\tgenes\tsubstrates\tsmiles\tsequence\tkcat'), ... + sprintf('R2_EXP_1\tG1\tm1\tsmiles\tseq\t12.5'), sprintf('R2_EXP_2\tG1\tNOTAREALMETABOLITE\tsmiles\tseq\t7')}); + verifyWarning(testCase, @() readDLKcatOutput(model, 'outFile', file, 'modelAdapter', adapter), ... + 'readDLKcatOutput:unknownSubstrate') + state = warning('off', 'readDLKcatOutput:unknownSubstrate'); + restore = onCleanup(@() warning(state)); + kcatList = readDLKcatOutput(model, 'outFile', file, 'modelAdapter', adapter); + verifyEqual(testCase, kcatList.rxns, {'R2_EXP_1'}) + verifyError(testCase, @() readDLKcatOutput(model, 'outFile', file, 'modelAdapter', adapter, ... + 'strict', true), 'readDLKcatOutput:unknownSubstrate') +end + +function testWriteDLKcatInputEmptySelection_tc0305(testCase) + % A selection without a reaction writes an empty file and returns no + % rows; the rows of a selection follow model.ec.rxns. + [model, adapter, project] = kcatProject(); + file = fullfile(project, 'DLKcat_in.tsv'); + none = false(numel(model.ec.rxns), 1); + evalc(['written = writeDLKcatInput(model, ''ecRxns'', none, ''modelAdapter'', adapter, ' ... + '''onlyWithSmiles'', false, ''filename'', file, ''overwrite'', true);']); + verifyEqual(testCase, size(written), [6 0]) + info = dir(file); + verifyEqual(testCase, info.bytes, 0) + some = ismember(model.ec.rxns, {'R5', 'R3'}); + evalc(['written = writeDLKcatInput(model, ''ecRxns'', some, ''modelAdapter'', adapter, ' ... + '''onlyWithSmiles'', false, ''filename'', file, ''overwrite'', true);']); + order = find(some); + verifyEqual(testCase, unique(written(1, :), 'stable'), model.ec.rxns(order)') +end + +function testKcatAssignmentConfigRejectsInvalidValues_tc0306(testCase) + % An empty preset, a criteria that is not one of the lower case names + % and a stage whose sources is not a list raise. + config = @(a) kcatAssignmentConfig(struct('kcat_assignment', a)); + verifyError(testCase, @() config(struct('preset', '')), 'kcatAssignment:config') + verifyError(testCase, @() config(struct('stage', struct('sources', 'custom'))), 'kcatAssignment:config') + verifyError(testCase, @() config(struct('stage', struct('sources', {{'custom'}}, 'criteria', 'Median'))), ... + 'kcatAssignment:config') + verifyError(testCase, @() config(struct('stage', struct('sources', {{'custom'}}, 'criteria', 'med'))), ... + 'kcatAssignment:config') + c = config(struct('stage', struct('sources', {{'custom'}}, 'criteria', 'median'))); + verifyEqual(testCase, c.stages.criteria, 'median') + verifyEqual(testCase, config(struct()).preset, 'brenda_ec_tree') +end + +function testEcTreeEstimateRejectsNaNK_tc0307(testCase) + m = struct('ec', {{'1.1.1.1'; '1.1.1.1'}}, 'log10kcat', [1; 2]); + verifyError(testCase, @() ecTreeEstimate({'1.1.1.1'}, m, NaN), 'ecTreeEstimate:k') +end + +function testKcatsFromECTreeSubset_tc0308(testCase) + % An explicit empty ecRxns selects no reaction; a reaction named twice + % gives one row. + [model, adapter] = kcatProject(); + ecs = unique(strtrim(split(strjoin(model.ec.eccodes(~cellfun(@isempty, model.ec.eccodes)), ';'), ';'))); + ecs = ecs(~cellfun(@isempty, ecs)); + v = repelem((1:numel(ecs))', 2); + m = struct('ec', {repelem(ecs, 2)}, 'log10kcat', v, 'kcat', 10 .^ v, 'release', 'BRENDA release test'); + withEc = find(~cellfun(@isempty, model.ec.eccodes)); + verifyGreaterThanOrEqual(testCase, numel(withEc), 2) + everything = kcatsFromECTree(model, 'measurements', m, 'save', false, 'modelAdapter', adapter); + verifyEqual(testCase, numel(everything.rxns), numel(withEc)) + none = kcatsFromECTree(model, 'measurements', m, 'save', false, 'modelAdapter', adapter, 'ecRxns', []); + verifyEmpty(testCase, none.rxns) + twice = kcatsFromECTree(model, 'measurements', m, 'save', false, 'modelAdapter', adapter, ... + 'ecRxns', [withEc(1); withEc(2); withEc(2)]); + verifyEqual(testCase, twice.rxns, model.ec.rxns(withEc(1:2))) +end + +function testGetStandardKcatExchangeAndPseudoReactions_tc0309(testCase) + % R7 consumes two metabolites and produces none: an exchange reaction, + % without the standard enzyme. R8 is named like a pseudoreaction in + % another letter case. R6 is an ordinary reaction without a GPR. + adapter = ModelAdapterManager.getAdapter(fullfile(findGECKOroot, 'test', 'unit_tests', 'ecTestGEM', 'TestGEMAdapter.m')); + model = loadConventionalGEM('modelAdapter', adapter); + toAdd.rxns = {'R6'; 'R7'; 'R8'}; + toAdd.rxnNames = {'R6'; 'R7'; 'Biomass Pseudoreaction'}; + toAdd.equations = {'m1[c] => m2[c]'; 'm1[c] + m2[c] =>'; 'm1[c] => m2[c]'}; + toAdd.grRules = {''; ''; ''}; + model = addRxns(model, toAdd, 3); + ecModel = makeEcModel(model, false, adapter); + ecModel = getECfromGEM(ecModel); + ecModel.ec.kcat(:) = 10; + evalc('ecModel = getStandardKcat(ecModel, ''modelAdapter'', adapter);'); + verifyTrue(testCase, ismember('R6', ecModel.ec.rxns)) + verifyFalse(testCase, ismember('R7', ecModel.ec.rxns)) + verifyFalse(testCase, ismember('R8', ecModel.ec.rxns)) +end + +function testGetStandardKcatLightModelTwice_tc0310(testCase) + % The standard pseudoenzyme of a light model is not added again, and the + % second call gives the first call's result. + adapter = ModelAdapterManager.getAdapter(fullfile(findGECKOroot, 'test', 'unit_tests', 'ecTestGEM', 'TestGEMAdapter.m')); + model = loadConventionalGEM('modelAdapter', adapter); + toAdd.rxns = {'R6'}; + toAdd.equations = {'m1[c] => m2[c]'}; + toAdd.grRules = {''}; + model = addRxns(model, toAdd, 3); + ecModel = makeEcModel(model, true, adapter); + ecModel = getECfromGEM(ecModel); + ecModel.ec.kcat(:) = 10; + evalc('first = getStandardKcat(ecModel, ''modelAdapter'', adapter);'); + evalc('second = getStandardKcat(first, ''modelAdapter'', adapter);'); + verifyEqual(testCase, sum(strcmp(second.ec.enzymes, 'standard')), 1) + verifyEqual(testCase, sort(second.ec.rxns), sort(first.ec.rxns)) + verifyEqual(testCase, sort(second.ec.kcat), sort(first.ec.kcat)) +end + +function testAssignKcatValuesWritesSourceWithMatchDetail_tc0311(testCase) + % ec.source is the source in lower case snake_case, followed by the + % wildcard level and origin of a BRENDA match in brackets, as geckopy + % writes it. + [model, ~] = kcatProject(); + rxns = model.ec.rxns(1:4); + kcatList = struct('source', 'x', 'rxns', {rxns}, 'kcats', [5; 6; 7; 8], ... + 'kcatSource', {{'BRENDA'; 'DLKcat'; 'OKP-CataPro'; 'brenda'}}, ... + 'wildcardLvl', [0; NaN; NaN; 2], 'origin', [1; NaN; 3; NaN]); + model = assignKcatValues(model, kcatList); + verifyEqual(testCase, model.ec.source(1:4), {'brenda (wc=0, origin=1)'; 'dlkcat'; 'okp_catapro'; 'brenda (wc=2)'}) +end + +function testResolveTunableContextMatchesSourceBeforeDetail_tc0312(testCase) + % A source with a detail is in the group of its name: 'brenda (wc=0, + % origin=1)' in brenda and 'combined (sd=0.10, n=2)' in combined, with + % that group's width; a source that no group names keeps the default. + [model, ~] = kcatProject(); + model.ec.kcat(1:4) = 10; + model.ec.source(1:4) = {'brenda (wc=0, origin=1)'; 'combined (sd=0.10, n=2)'; 'DLKcat'; 'other (x)'}; + params = struct('kcatSources', {{'brenda', 'combined', 'dlkcat'}}, 'sigma0logSource', [0.2; 0.3; 0.4], ... + 'sigma0logDefault', 0.5, 'tieIsozymes', false); + mask = false(numel(model.ec.rxns), 1); + mask(1:4) = true; + [~, ~, ~, groups, sigma0log] = resolveTunableContext(model, params, mask); + verifyEqual(testCase, groups, {'brenda'; 'combined'; 'dlkcat'; 'unlabelled'}) + verifyEqual(testCase, sigma0log, [0.2; 0.3; 0.4; 0.5]) +end + +function [model, adapter, project] = kcatProject() + adapter = ModelAdapterManager.getAdapter(fullfile(findGECKOroot, 'test', 'unit_tests', 'ecTestGEM', 'TestGEMAdapter.m')); + project = tempname; + copyfile(fullfile(adapter.params.path, 'data'), fullfile(project, 'data')); + delete(fullfile(project, 'data', 'customKcats.tsv')); + mkdir(fullfile(project, 'data', 'kcats')); + adapter.params.path = project; + model = makeEcModel(getGeckoTestModel(), false, adapter); + model = getECfromGEM(model); +end + +function writeLines(file, lines) + fid = fopen(file, 'w'); + fprintf(fid, '%s\n', lines{:}); + fclose(fid); +end diff --git a/test/unit_tests/kcatListTests.m b/test/unit_tests/kcatListTests.m new file mode 100644 index 00000000..db343938 --- /dev/null +++ b/test/unit_tests/kcatListTests.m @@ -0,0 +1,57 @@ +%run this test case with the command +%results = runtests('kcatListTests.m') + +function tests = kcatListTests + tests = functiontests(localfunctions); +end + +function testAssignKcatValuesSourceAfterZeroRows_tc0104(testCase) + % Rows with a zero kcat are dropped together with their source. + adapter = getTestAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + kcatList = struct(); + kcatList.source = 'test'; + kcatList.rxns = ecModel.ec.rxns(1:2); + kcatList.kcats = [0; 5]; + kcatList.kcatSource = {'a'; 'b'}; + ecModel = assignKcatValues(ecModel, kcatList); + verifyEqual(testCase, ecModel.ec.kcat(2), 5) + verifyEqual(testCase, ecModel.ec.source{2}, 'b') + verifyEqual(testCase, ecModel.ec.kcat(1), 0) +end + +function testLoadBRENDAdataLowercaseEc_tc0105(testCase) + % An EC code with a lowercase letter (provisional EC numbers end in n) + % is found in the molecular weight table. + adapter = getTestAdapter(); + scratchDir = tempname; + cleanupDir = onCleanup(@() rmdir(scratchDir, 's')); + mkdir(fullfile(scratchDir,'data')); + writeTable(fullfile(scratchDir,'data','kcat.tsv'), ... + 'ec_code\tsubstrate\torganism\tkcat_max\tkcat_median\tn\treferences\n', ... + '3.5.1.n3\tm1\ttestorg\t99\t5\t3\tPMID:1\n'); + writeTable(fullfile(scratchDir,'data','mw.tsv'), ... + 'ec_code\tsubstrate\torganism\tmw\tn\treferences\n', ... + '3.5.1.n3\t*\ttestorg\t60000\t1\t*\n'); + writeTable(fullfile(scratchDir,'data','sa.tsv'), ... + 'ec_code\tsubstrate\torganism\tsa_max\tsa_median\tn\treferences\n', ... + '3.5.1.n3\t*\ttestorg\t120\t7\t2\tPMID:2\n'); + brendaAdapter = adapter; + brendaAdapter.params.path = scratchDir; + [~, SAcell] = loadBRENDAdata('modelAdapter', brendaAdapter); + verifyEqual(testCase, SAcell{1}, {'3.5.1.n3'}) + verifyEqual(testCase, SAcell{3}, (120/60) * (60000/1000), 'AbsTol', 1e-9) +end + +function adapter = getTestAdapter() + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); +end + +function writeTable(file, header, row) + fid = fopen(file, 'w'); + fprintf(fid, '# BRENDA release test-fixture\n'); + fprintf(fid, header); + fprintf(fid, row); + fclose(fid); +end diff --git a/test/unit_tests/kcatMatchTests.m b/test/unit_tests/kcatMatchTests.m new file mode 100644 index 00000000..3ec73a03 --- /dev/null +++ b/test/unit_tests/kcatMatchTests.m @@ -0,0 +1,260 @@ +%run this test case with the command +%results = runtests('kcatMatchTests.m') + +function tests = kcatMatchTests + tests = functiontests(localfunctions); +end + +function testLoadBRENDAdataDropsKcatFarBelowItsEc_tc0220(testCase) + % A kcat more than four orders of magnitude below the median of its EC + % is dropped by default and kept when the filter is switched off. + adapter = brendaAdapter(testCase, ... + [kcatRows('1.1.1.1', {'o1','o2','o3','o4','o5','o6'}, 10, 10), ... + kcatRows('1.1.1.1', {'o7'}, 1e-4, 1e-4)]); + KCATcell = loadBRENDAdata('modelAdapter', adapter); + verifyEqual(testCase, KCATcell{4}, repmat(10,6,1)) + KCATcell = loadBRENDAdata('modelAdapter', adapter, 'filterOutlierKcats', false); + verifyEqual(testCase, sort(KCATcell{4}), sort([repmat(10,6,1); 1e-4])) +end + +function testLoadBRENDAdataReferenceUsesMaxAndMedian_tc0221(testCase) + % The reference of an EC is built from the max and the median values, + % whichever aggregation is read: a median that is far below its EC is an + % outlier even when the max of the same row is not. + adapter = brendaAdapter(testCase, ... + [kcatRows('2.1.1.1', {'o1','o2','o3','o4'}, 100, 100), ... + kcatRows('2.1.1.1', {'o5'}, 100, 0.001)]); + KCATcell = loadBRENDAdata('modelAdapter', adapter, 'kcatAggregation', 'median'); + verifyEqual(testCase, KCATcell{4}, repmat(100,4,1)) + KCATcell = loadBRENDAdata('modelAdapter', adapter, 'kcatAggregation', 'max'); + verifyEqual(testCase, KCATcell{4}, repmat(100,5,1)) +end + +function testLoadBRENDAdataReferenceNeedsFiveValues_tc0222(testCase) + % The values of the max and the median of a row both count towards the + % reference of its EC. With fewer than five of them at every EC level + % there is no reference and no row is dropped; with five or more at a + % shorter EC prefix, that prefix is the reference. + adapter = brendaAdapter(testCase, ... + [kcatRows('3.1.1.1', {'o1'}, 10, 10), kcatRows('3.1.1.1', {'o2'}, 1e-9, 1e-9)]); + KCATcell = loadBRENDAdata('modelAdapter', adapter); + verifyEqual(testCase, numel(KCATcell{4}), 2) + adapter = brendaAdapter(testCase, ... + [kcatRows('4.1.1.2', {'o1','o2','o3'}, 10, 10), kcatRows('4.1.1.1', {'o4'}, 1e-9, 1e-9)]); + KCATcell = loadBRENDAdata('modelAdapter', adapter); + verifyEqual(testCase, KCATcell{4}, repmat(10,3,1)) +end + +function testFuzzyKcatMatchingFullWildcard_tc0223(testCase) + % An EC number without any match at the wildcard levels 1 to 3 is matched + % against every EC number in BRENDA, at wildcard level 4. + [ecModel, fuzzyAdapter] = fuzzyModel(testCase, {'5.5.5.5\tm1\ttestus testus\t42\t42\t1\t*\n'}); + ecModel.ec.eccodes{strcmp(ecModel.ec.rxns, 'R2_EXP_1')} = '9.9.9.9'; + kcatList = fuzzyKcatMatching(ecModel, ismember(ecModel.ec.rxns,{'R2_EXP_1'}), fuzzyAdapter); + verifyEqual(testCase, kcatList.kcats, 42) + verifyEqual(testCase, kcatList.wildcardLvl, 4) +end + +function testFuzzyKcatMatchingTieReportsTheSelectedEc_tc0224(testCase) + % Two EC numbers of a reaction give the same kcat, one through a wildcard + % and one exactly: the wildcard level and origin are those of the exact one. + [ecModel, fuzzyAdapter] = fuzzyModel(testCase, ... + {'1.1.1.1\tm1\ttestus testus\t7\t7\t1\t*\n', ... + '1.1.1.9\tm1\ttestus testus\t7\t7\t1\t*\n'}); + ecModel.ec.eccodes{strcmp(ecModel.ec.rxns, 'R2_EXP_1')} = '1.1.1.5;1.1.1.1'; + kcatList = fuzzyKcatMatching(ecModel, ismember(ecModel.ec.rxns,{'R2_EXP_1'}), fuzzyAdapter); + verifyEqual(testCase, kcatList.kcats, 7) + verifyEqual(testCase, kcatList.wildcardLvl, 0) + verifyEqual(testCase, kcatList.origin, 1) +end + +function testFuzzyKcatMatchingSubsetKeepsOrderAndRepeats_tc0225(testCase) + % Indices select the reactions in the order given, a repeated index + % gives a repeated reaction, and a logical vector gives model order. + [ecModel, fuzzyAdapter] = fuzzyModel(testCase, {'1.1.1.1\tm1\ttestus testus\t7\t7\t1\t*\n'}); + ids = {'R3','R2_EXP_1','R2_EXP_1'}; + idx = cellfun(@(r) find(strcmp(ecModel.ec.rxns, r)), ids); + kcatList = fuzzyKcatMatching(ecModel, 'ecRxns', idx, 'modelAdapter', fuzzyAdapter); + verifyEqual(testCase, kcatList.rxns(:)', ids) + verifyEqual(testCase, numel(kcatList.kcats), 3) + kcatList = fuzzyKcatMatching(ecModel, 'ecRxns', ismember(ecModel.ec.rxns, ids), ... + 'modelAdapter', fuzzyAdapter); + verifyEqual(testCase, kcatList.rxns, ecModel.ec.rxns(ismember(ecModel.ec.rxns, ids))) +end + +function testFuzzyKcatMatchingEmptySubsetSelectsNone_tc0226(testCase) + % [] selects all reactions; any other empty selection selects none. + [ecModel, fuzzyAdapter] = fuzzyModel(testCase, {'1.1.1.1\tm1\ttestus testus\t7\t7\t1\t*\n'}); + kcatList = fuzzyKcatMatching(ecModel, 'ecRxns', [], 'modelAdapter', fuzzyAdapter); + verifyEqual(testCase, numel(kcatList.rxns), numel(ecModel.ec.rxns)) + kcatList = fuzzyKcatMatching(ecModel, 'ecRxns', zeros(0,1), 'modelAdapter', fuzzyAdapter); + verifyEmpty(testCase, kcatList.rxns) + verifyEmpty(testCase, kcatList.kcats) + kcatList = fuzzyKcatMatching(ecModel, 'ecRxns', false(numel(ecModel.ec.rxns),1), ... + 'modelAdapter', fuzzyAdapter); + verifyEmpty(testCase, kcatList.rxns) + adapter = getTestAdapter(); + verifyError(testCase, @() kcatsFromBrenda(ecModel, 'ecRxns', zeros(0,1), 'save', false, ... + 'modelAdapter', adapter), 'kcatsFromBrenda:emptySubset') +end + +function testFuzzyKcatMatchingForceWildcardEscalatesFromTheRight_tc0231(testCase) + % forceWClvl replaces the rightmost level that is not a wildcard yet, for + % every EC number of a reaction, also a provisional one: level 4 gives + % -.-.-.- and level 1 gives a wildcard at the last level. + [ecModel, fuzzyAdapter] = fuzzyModel(testCase, {'1.1.1.1\tm1\ttestus testus\t7\t7\t1\t*\n'}); + ecModel.ec.eccodes{strcmp(ecModel.ec.rxns, 'R2_EXP_1')} = '1.1.1.1;3.5.1.n3'; + sel = ismember(ecModel.ec.rxns,{'R2_EXP_1'}); + kcatList = fuzzyKcatMatching(ecModel, 'ecRxns', sel, 'modelAdapter', fuzzyAdapter, 'forceWClvl', 1); + verifyEqual(testCase, kcatList.eccodes, {'1.1.1.-;3.5.1.-'}) + kcatList = fuzzyKcatMatching(ecModel, 'ecRxns', sel, 'modelAdapter', fuzzyAdapter, 'forceWClvl', 4); + verifyEqual(testCase, kcatList.eccodes, {'-.-.-.-;-.-.-.-'}) + + % A code with a trailing wildcard escalates from the last level that is not + % a wildcard yet, and a level above the number of levels left stops at -.-.-.- + ecModel.ec.eccodes{strcmp(ecModel.ec.rxns, 'R2_EXP_1')} = '1.1.-.-;3.5.1.n3'; + kcatList = fuzzyKcatMatching(ecModel, 'ecRxns', sel, 'modelAdapter', fuzzyAdapter, 'forceWClvl', 1); + verifyEqual(testCase, kcatList.eccodes, {'1.-.-.-;3.5.1.-'}) + kcatList = fuzzyKcatMatching(ecModel, 'ecRxns', sel, 'modelAdapter', fuzzyAdapter, 'forceWClvl', 6); + verifyEqual(testCase, kcatList.eccodes, {'-.-.-.-;-.-.-.-'}) +end + +function testFuzzyKcatMatchingEcCodeWithoutFourLevels_tc0239(testCase) + % An EC code without four levels is not escalated level by level: it is + % left as it is by forceWClvl and, when BRENDA has no match, ends with the + % no-match values instead of an error. + [ecModel, fuzzyAdapter] = fuzzyModel(testCase, {'1.1.1.1\tm1\ttestus testus\t7\t7\t1\t*\n'}); + ecModel.ec.eccodes{strcmp(ecModel.ec.rxns, 'R2_EXP_1')} = '9.9.9'; + sel = ismember(ecModel.ec.rxns,{'R2_EXP_1'}); + kcatList = fuzzyKcatMatching(ecModel, 'ecRxns', sel, 'modelAdapter', fuzzyAdapter); + verifyEqual(testCase, kcatList.eccodes, {'9.9.9'}) + verifyEqual(testCase, kcatList.kcats, 0) + kcatList = fuzzyKcatMatching(ecModel, 'ecRxns', sel, 'modelAdapter', fuzzyAdapter, 'forceWClvl', 1); + verifyEqual(testCase, kcatList.eccodes, {'9.9.9'}) + verifyEqual(testCase, kcatList.kcats, 0) +end + +function testApplyCustomKcatsSkipsABlankKcat_tc0227(testCase) + % An entry without a kcat leaves the reaction as it is. + [ecModel, adapter] = customModel(); + isR3 = strcmp(ecModel.ec.rxns,'R3'); + isR2 = strcmp(ecModel.ec.rxns,'R2_EXP_1'); + custom = customStruct({''; ''}, [NaN; 50], {'R3'; 'R2'}, {'';''}); + ecModel = applyCustomKcats(ecModel, custom, adapter); + verifyEqual(testCase, ecModel.ec.kcat(isR3), 10) + verifyFalse(testCase, strcmp(ecModel.ec.source{isR3}, 'custom')) + verifyEqual(testCase, ecModel.ec.kcat(isR2), 50) + verifyEqual(testCase, ecModel.ec.source{isR2}, 'custom') +end + +function testApplyCustomKcatsEmptyNoteIsNotAppended_tc0228(testCase) + % An empty note does not add a separator to the note of the reaction. + [ecModel, adapter] = customModel(); + custom = customStruct({''; ''}, [50; 60], {'R3'; 'R3'}, {'first'; ''}); + ecModel = applyCustomKcats(ecModel, custom, adapter); + verifyEqual(testCase, ecModel.ec.notes{strcmp(ecModel.ec.rxns,'R3')}, 'first') + custom = customStruct({''; ''}, [50; 60], {'R3'; 'R3'}, {''; 'second'}); + ecModel = applyCustomKcats(customModelAgain(), custom, adapter); + verifyEqual(testCase, ecModel.ec.notes{strcmp(ecModel.ec.rxns,'R3')}, 'second') +end + +function testApplyCustomKcatsMatchesIdsExactly_tc0229(testCase) + % Protein and reaction ids are case sensitive. + [ecModel, adapter] = customModel(); + before = ecModel.ec.kcat; + custom = customStruct({'p3'}, 123, {''}, {''}); + updated = applyCustomKcats(ecModel, custom, adapter); + verifyEqual(testCase, updated.ec.kcat, before) + custom = customStruct({'P3'}, 123, {'r3'}, {''}); + updated = applyCustomKcats(ecModel, custom, adapter); + verifyEqual(testCase, updated.ec.kcat, before) + custom = customStruct({'P3'}, 123, {''}, {''}); + updated = applyCustomKcats(ecModel, custom, adapter); + verifyTrue(testCase, any(updated.ec.kcat == 123)) +end + +function testApplyCustomKcatsLightModel_tc0230(testCase) + % A light ecModel is updated by the proteins of its rows, and all three + % outputs are returned. + adapter = getTestAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), true, adapter); + ecModel = getECfromGEM(ecModel); + custom = customStruct({'P3'}, 123, {''}, {'light'}); + [updated, rxnUpdated, notMatch] = applyCustomKcats(ecModel, custom, adapter); + verifyNotEmpty(testCase, rxnUpdated) + verifyTrue(testCase, all(updated.ec.kcat(ismember(updated.ec.rxns, rxnUpdated)) == 123)) + verifyTrue(testCase, istable(notMatch)) +end + +%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%% + +function adapter = getTestAdapter() + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); +end + +function rows = kcatRows(ec, organisms, kcatMax, kcatMedian) + rows = cell(1, numel(organisms)); + for i = 1:numel(organisms) + rows{i} = sprintf('%s\tm1\t%s\t%g\t%g\t1\t*\n', ec, organisms{i}, kcatMax, kcatMedian); + end +end + +function writeBrenda(brendaDir, kcatLines) + fid = fopen(fullfile(brendaDir, 'kcat.tsv'), 'w'); + fprintf(fid, '# BRENDA release test-fixture - kcat in 1/s\n'); + fprintf(fid, 'ec_code\tsubstrate\torganism\tkcat_max\tkcat_median\tn\treferences\n'); + for i = 1:numel(kcatLines) + fprintf(fid, kcatLines{i}); + end + fclose(fid); + fid = fopen(fullfile(brendaDir, 'mw.tsv'), 'w'); + fprintf(fid, '# BRENDA release test-fixture - molecular weight in g/mol\n'); + fprintf(fid, 'ec_code\tsubstrate\torganism\tmw\tn\treferences\n'); + fprintf(fid, '0.0.0.0\t*\tplaceholder\t1\t1\t*\n'); + fclose(fid); + fid = fopen(fullfile(brendaDir, 'sa.tsv'), 'w'); + fprintf(fid, '# BRENDA release test-fixture - specific activity in umol/min/mg\n'); + fprintf(fid, 'ec_code\tsubstrate\torganism\tsa_max\tsa_median\tn\treferences\n'); + fprintf(fid, '0.0.0.0\t*\tplaceholder\t1\t1\t1\t*\n'); + fclose(fid); +end + +function adapter = brendaAdapter(testCase, kcatLines) + scratchDir = tempname; + brendaDir = fullfile(scratchDir, 'data'); + mkdir(brendaDir); + testCase.addTeardown(@() rmdir(scratchDir, 's')); + writeBrenda(brendaDir, kcatLines); + adapter = getTestAdapter(); + adapter.params.path = scratchDir; +end + +function [ecModel, fuzzyAdapter] = fuzzyModel(testCase, kcatLines) + fuzzyAdapter = brendaAdapter(testCase, kcatLines); + geckoPath = findGECKOroot; + copyfile(fullfile(geckoPath,'test','unit_tests','ecTestGEM','data','PhylDist.mat'), ... + fullfile(fuzzyAdapter.params.path, 'data', 'PhylDist.mat')); + adapter = getTestAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + ecModel = getECfromGEM(ecModel); +end + +function [ecModel, adapter] = customModel() + adapter = getTestAdapter(); + ecModel = customModelAgain(); +end + +function ecModel = customModelAgain() + adapter = getTestAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + ecModel = getECfromGEM(ecModel); + ecModel.ec.kcat(:) = 10; +end + +function custom = customStruct(proteins, kcats, rxns, notes) + custom.proteins = proteins; + custom.kcat = kcats; + custom.rxns = rxns; + custom.notes = notes; +end diff --git a/test/unit_tests/kcatSourceTests.m b/test/unit_tests/kcatSourceTests.m new file mode 100644 index 00000000..d40829f1 --- /dev/null +++ b/test/unit_tests/kcatSourceTests.m @@ -0,0 +1,286 @@ +%run this test case with the command +%results = runtests('kcatSourceTests.m') + +function tests = kcatSourceTests + tests = functiontests(localfunctions); +end + +function testGetEcRxnKeys_tc0070(testCase) + % Full and light models give the same conventional reactions and + % enzyme sets. + [full, light] = buildKcatModels(); + [baseF, enzF] = getEcRxnKeys(full); + [baseL, enzL] = getEcRxnKeys(light); + verifyEqual(testCase, baseF(strcmp(full.ec.rxns, 'R2_EXP_1')), {'R2'}) + verifyEqual(testCase, baseF(strcmp(full.ec.rxns, 'R2_REV_EXP_2')), {'R2_REV'}) + verifyEqual(testCase, sort(unique(strcat(baseF, '|', enzF))), sort(unique(strcat(baseL, '|', enzL)))) + for i = 1:numel(enzF) + parts = strsplit(enzF{i}, ' + '); + verifyEqual(testCase, parts, sort(parts)) + end +end + +function testSaveLoadRoundTrip_tc0071(testCase) + % What saveKcatSource writes, loadKcatSource maps back to the same + % model.ec rows and values. + [full, ~, adapter] = buildKcatModels(); + list = fuzzyKcatMatching(full, [], adapter); + folder = tempname; + file = saveKcatSource(full, list, 'brenda', 'folder', folder, ... + 'parameters', struct('aggregation','max'), 'data', 'BRENDA release test'); + [records, meta] = rowsOf(full, file); + verifyEqual(testCase, meta.source, 'brenda') + verifyEqual(testCase, meta.kind, 'gathered') + verifyEqual(testCase, meta.data, 'BRENDA release test') + verifyEqual(testCase, meta.parameters, '{"aggregation":"max"}') + keep = list.kcats > 0; + verifyEqual(testCase, numel(records.kcat), sum(keep)) + loaded = loadKcatSource(full, file); + verifyEqual(testCase, sort(loaded.rxns), sort(list.rxns(keep))) + [~, a] = sort(list.rxns(keep)); [~, b] = sort(loaded.rxns); + kept = find(keep); + verifyEqual(testCase, loaded.kcats(b), list.kcats(kept(a))) + verifyEqual(testCase, loaded.wildcardLvl(b), list.wildcardLvl(kept(a))) + verifyEqual(testCase, loaded.origin(b), list.origin(kept(a))) + verifyEqual(testCase, loaded.source, 'brenda') + subs = list.substrates(kept(a)); + verifyEqual(testCase, loaded.substrates(b), cellfun(@(c) strjoin(c, '; '), subs, 'UniformOutput', false)) + verifyEqual(testCase, loaded.eccodes(b), list.eccodes(kept(a))) + % Rows are sorted, so a rebuilt model writes the same file. + sorted = sortrows([records.rxn records.enzymes records.substrate records.source]); + verifyEqual(testCase, [records.rxn records.enzymes records.substrate records.source], sorted) +end + +function testFullFileOnLightModel_tc0072(testCase) + % A file written from the full model applies to the light model. + [full, light, adapter] = buildKcatModels(); + list = fuzzyKcatMatching(full, [], adapter); + file = saveKcatSource(full, list, 'brenda', 'folder', tempname); + [loaded, report] = loadKcatSource(light, file); + verifyEmpty(testCase, report.unmatched) + [baseL, enzL] = getEcRxnKeys(light); + records = rowsOf(light, file); + for r = 1:numel(records.kcat) + hit = strcmp(baseL, records.rxn{r}) & strcmp(enzL, records.enzymes{r}); + verifyEqual(testCase, sort(loaded.rxns(loaded.line == records.line(r))), sort(light.ec.rxns(hit))) + end +end + +function testMatchingRules_tc0073(testCase) + % Rows with only enzymes or only a reaction, unmatched and partial rows. + [full, ~, adapter] = buildKcatModels(); + [base, enz] = getEcRxnKeys(full); + multi = find(contains(enz, ' + '), 1); + parts = strsplit(enz{multi}, ' + '); + folder = tempname; mkdir(folder); + file = fullfile(folder, 'custom.tsv'); + fid = fopen(file, 'w'); + fprintf(fid, '# source: custom\n# kind: curated\n'); + fprintf(fid, 'rxn\tenzymes\tsubstrate\tkcat\tlog10_sd\tsource\tdetail\tec_code\tnote\n'); + fprintf(fid, '\t%s\t\t10\t\tcustom\t\t\tenzymes only, reversed order\n', strjoin(fliplr(parts), ' + ')); + fprintf(fid, '%s\t\t\t20\t\tcustom\t\t\treaction only\n', base{multi}); + fprintf(fid, 'R999\tX1\t\t30\t\tcustom\t\t\tunmatched\n'); + fprintf(fid, '%s\t%s + XNEW\t\t40\t\tcustom\t\t\tpartial\n', base{multi}, enz{multi}); + fclose(fid); + [loaded, report] = loadKcatSource(full, file); + verifyEqual(testCase, sort(loaded.rxns(loaded.line == 4)), sort(full.ec.rxns(strcmp(enz, enz{multi})))) + verifyEqual(testCase, sort(loaded.rxns(loaded.line == 5)), sort(full.ec.rxns(strcmp(base, base{multi})))) + verifyEqual(testCase, report.unmatched.line, [6; 7]) + verifyEqual(testCase, unique(report.partial.line), 7) + % Curated files are never written: by name, by 'kind: curated' and by + % 'source: custom', in any case, and the file is left as it was. + list = fuzzyKcatMatching(full, [], adapter); + before = fileread(file); + verifyError(testCase, @() saveKcatSource(full, list, 'custom', 'folder', folder), 'saveKcatSource:curated') + verifyEqual(testCase, fileread(file), before) + writeLines(fullfile(folder, 'mine.tsv'), {'# source: Custom', 'rxn kcat source'}); + verifyError(testCase, @() saveKcatSource(full, list, 'mine', 'folder', folder), 'saveKcatSource:curated') + writeLines(fullfile(folder, 'mine2.tsv'), {'# kind: Curated', 'rxn kcat source'}); + verifyError(testCase, @() saveKcatSource(full, list, 'mine2', 'folder', folder), 'saveKcatSource:curated') +end + +function testKcatsFromBrendaAndDLKcat_tc0074(testCase) + % The source functions write their files into data/kcats. + [full, ~, adapter] = buildKcatModels(); + project = tempname; + copyfile(fullfile(adapter.params.path, 'data'), fullfile(project, 'data')); + adapter.params.path = project; + list = kcatsFromBrenda(full, 'aggregation', 'median', 'modelAdapter', adapter); + [records, meta] = rowsOf(full, fullfile(project, 'data', 'kcats', 'brenda.tsv')); + verifyEqual(testCase, meta.generator(1:15), 'kcatsFromBrenda') + verifyEqual(testCase, meta.parameters, '{"aggregation":"median","force_wildcard_level":0}') + verifyEqual(testCase, meta.data, 'BRENDA release test-fixture') + verifyEqual(testCase, numel(records.kcat), sum(list.kcats > 0)) + + % DLKcat output for this model, read without running DLKcat. + rows = {'R2_EXP_1','G1','m1','C','MRAL','12.5'; 'R3','G4','m1','C','MDFM','3.25'}; + fid = fopen(fullfile(project, 'data', 'DLKcat.tsv'), 'w'); + fprintf(fid, 'rxns\tgenes\tsubstrates\tsmiles\tsequence\tkcat\n'); + for i = 1:size(rows, 1) + fprintf(fid, '%s\t%s\t%s\t%s\t%s\t%s\n', rows{i,:}); + end + fclose(fid); + kcatsFromDLKcat(full, 'modelAdapter', adapter); + [records, meta] = rowsOf(full, fullfile(project, 'data', 'kcats', 'dlkcat.tsv')); + verifyEqual(testCase, meta.source, 'dlkcat') + verifyEqual(testCase, sort(records.kcat), [3.25; 12.5]) + verifyEqual(testCase, unique(records.source), {'DLKcat'}) +end + +function testKcatsFromOKPStored_tc0075(testCase) + % Stored OKP results: a method's own result of its current job, or a + % result stored by fetchOpenKineticsPredictor alone when its predictions + % are of the requested method. + [full, ~, adapter] = buildKcatModels(); + full.metSmiles = repmat({''}, numel(full.mets), 1); + full.metSmiles(strcmp(full.mets, 'm1c')) = {'C(C1C)O'}; + project = tempname; + copyfile(fullfile(adapter.params.path, 'data'), fullfile(project, 'data')); + adapter.params.path = project; + data = fullfile(project, 'data'); + okpCsv = {'kcat (1/s),Source kcat,Extra Info kcat,Protein Sequence,Substrate', ... + '12.5,Prediction from CataPro,,MRAL,C(C1C)O'}; + writeLines(fullfile(data, 'OKP_output.csv'), okpCsv); + writeLines(fullfile(data, 'OKP_job.txt'), {'jobId: abc123', 'method: CataPro'}); + [list, done] = kcatsFromOKP(full, 'method', "CataPro", 'useStored', true, 'modelAdapter', adapter); + verifyTrue(testCase, done) + [records, meta] = rowsOf(full, fullfile(data, 'kcats', 'okp_catapro.tsv')); + verifyEqual(testCase, meta.data, 'OKP job abc123') + verifyEqual(testCase, numel(records.kcat), sum(list.kcats > 0)) + verifyEqual(testCase, unique(records.source), {'OKP-CataPro'}) + verifyTrue(testCase, isfile(fullfile(data, 'OKP_output_catapro.csv'))) + + % The shared job file names UniKP, but the shared result holds CataPro + % predictions (fetched after UniKP was submitted): refused. + writeLines(fullfile(data, 'OKP_job.txt'), {'jobId: uni1', 'method: UniKP'}); + verifyError(testCase, @() kcatsFromOKP(full, 'method', 'UniKP', 'useStored', true, ... + 'modelAdapter', adapter), 'kcatsFromOKP:noStored') + verifyFalse(testCase, isfile(fullfile(data, 'kcats', 'okp_unikp.tsv'))) + % A method's stored result of an earlier job is refused too. + writeLines(fullfile(data, 'OKP_job_kinform_h.txt'), {'jobId: new2', 'method: KinForm-H', 'resultOf: old1'}); + writeLines(fullfile(data, 'OKP_output_kinform_h.csv'), okpCsv); + verifyError(testCase, @() kcatsFromOKP(full, 'method', 'KinForm-H', 'useStored', true, ... + 'modelAdapter', adapter), 'kcatsFromOKP:noStored') + % ecRxns when no job is submitted, and a misspelled option, are errors. + verifyError(testCase, @() kcatsFromOKP(full, 'method', 'CataPro', 'useStored', true, ... + 'ecRxns', true(numel(full.ec.rxns), 1), 'modelAdapter', adapter), 'kcatsFromOKP:ecRxns') + verifyError(testCase, @() kcatsFromOKP(full, 'method', 'UniKP', 'wiat', true, ... + 'modelAdapter', adapter), 'kcatsFromOKP:arguments') +end + +function testGuardsNumbersAndJson_tc0078(testCase) + [full, ~, adapter] = buildKcatModels(); + project = tempname; + copyfile(fullfile(adapter.params.path, 'data'), fullfile(project, 'data')); + adapter.params.path = project; + folder = fullfile(project, 'data', 'kcats'); + mkdir(folder); + % The curated guard reads quoted header lines and ignores the case of keys. + writeLines(fullfile(folder, 'a.tsv'), {'"# kind: curated"', 'rxn kcat source'}); + writeLines(fullfile(folder, 'b.tsv'), {'# Kind: Curated', 'rxn kcat source'}); + writeLines(fullfile(folder, 'c.tsv'), {'# SOURCE: custom', 'rxn kcat source'}); + list = fuzzyKcatMatching(full, [], adapter); + for f = {'a','b','c'} + verifyError(testCase, @() saveKcatSource(full, list, f{1}, 'modelAdapter', adapter), 'saveKcatSource:curated') + end + % The source functions check the file before they gather. + verifyError(testCase, @() kcatsFromBrenda(full, 'saveAs', "custom", 'modelAdapter', adapter), 'saveKcatSource:curated') + verifyError(testCase, @() kcatsFromDLKcat(full, 'ecRxns', true(numel(full.ec.rxns), 1), ... + 'modelAdapter', adapter), 'kcatsFromDLKcat:ecRxns') + + % Infinite, NaN and non-positive kcats are not written, and not applied. + list.kcats(1) = Inf; list.kcats(2) = NaN; list.kcats(3) = -2; + file = saveKcatSource(full, list, "numbers", 'modelAdapter', adapter, 'parameters', ... + struct('z', 1, 'a', struct('y', ['caf' char(233)], 'b', true), 'n', NaN, ... + 'f', 1/3, 'g', 1e-7, 'h', 1e15, 'k', 1e20, 'l', {{5}}, 's', 'tab quote"')); + [records, meta] = rowsOf(full, file); + verifyTrue(testCase, all(isfinite(records.kcat) & records.kcat > 0)) + % The same text as geckopy's test_parameters_json_matches_gecko. + verifyEqual(testCase, meta.parameters, ['{"a":{"b":true,"y":"caf' char(233) '"},"f":0.3333333333333333,' ... + '"g":1e-07,"h":1e+15,"k":1e+20,"l":[5],"n":null,"s":"tab\tquote\"","z":1}']) + writeLines(fullfile(folder, 'inf.tsv'), {'rxn enzymes kcat source', 'R3 P4 Inf custom', 'R3 P4 1e999 custom'}); + [loaded, report] = loadKcatSource(full, fullfile(folder, 'inf.tsv')); + verifyEmpty(testCase, loaded.rxns) + verifyEqual(testCase, report.invalid.line, [2; 3]) + + % Rows are sorted by every column, in the same order as geckopy. + writeLines(fullfile(folder, 'unsorted.tsv'), {'rxn enzymes substrate kcat source detail', ... + 'R3 P4 m1 2 b ', 'R3 P4 m1 2 a wc=1', 'R3 P4 5 a ', 'R2_REV P3 m2 1 a '}); + l2 = loadKcatSource(full, fullfile(folder, 'unsorted.tsv')); + file = saveKcatSource(full, l2, 'sorted', 'modelAdapter', adapter); + records = rowsOf(full, file); + verifyEqual(testCase, records.rxn', {'R2_REV','R3','R3','R3'}) + verifyEqual(testCase, records.substrate', {'m2','','m1','m1'}) + verifyEqual(testCase, records.source', {'a','a','a','b'}) +end + +function testEnzymelessRowsAndLightToFull_tc0076(testCase) + % Rows of reactions without enzymes are not written, so they cannot + % spread to their isozymes; a light-model file applies to the full model. + [full, light, adapter] = buildKcatModels(); + list = fuzzyKcatMatching(full, [], adapter); + i = find(strcmp(full.ec.rxns, 'R2_EXP_2')); + full.ec.rxnEnzMat(i, :) = 0; + file = saveKcatSource(full, list, 'brenda', 'folder', tempname); + loaded = loadKcatSource(full, file); + verifyFalse(testCase, any(strcmp(loaded.rxns, 'R2_EXP_2'))) + verifyEqual(testCase, sum(strcmp(loaded.rxns, 'R2_EXP_1')), 1) + + listL = fuzzyKcatMatching(light, [], adapter); + fileL = saveKcatSource(light, listL, 'brenda', 'folder', tempname); + fullAgain = buildKcatModels(); + [~, report] = loadKcatSource(fullAgain, fileL); + verifyEmpty(testCase, report.unmatched) +end + +function testSharedFixture_tc0077(testCase) + % The fixture file, read the same way by geckopy: byte-order mark, CRLF, + % a quoted header line and field, comments and blank lines between + % rows, a row of tabs, a decimal comma, a negative kcat. + file = fullfile(findGECKOroot, 'test', 'unit_tests', 'ecTestGEM', 'data', 'kcatSourceFixture.tsv'); + [full] = buildKcatModels(); + [records, meta] = rowsOf(full, file); + verifyEqual(testCase, meta.source, 'fixture') + verifyEqual(testCase, meta.parameters, '{"aggregation":"median"}') + verifyEqual(testCase, meta.kind, 'curated') + verifyEqual(testCase, records.line', [7 9 11 12 13 14 15]) + verifyEqual(testCase, records.rxn', {'R2','R3','R5','R2_REV','','R9','R9'}) + verifyEqual(testCase, records.substrate{2}, '2,3-bisphospho-D-glycerate') + verifyEqual(testCase, records.kcat', [12.5 1e-05 NaN 7 3 -1 4]) + verifyEqual(testCase, records.log10_sd(1), 0.3) + + [loaded, report] = loadKcatSource(full, file); + verifyEqual(testCase, loaded.rxns(loaded.line == 7), {'R2_EXP_1'}) + verifyEqual(testCase, sort(loaded.rxns(loaded.line == 12)), {'R2_REV_EXP_1';'R2_REV_EXP_2'}) + verifyEqual(testCase, sort(loaded.rxns(loaded.line == 13)), {'R2_EXP_2';'R2_REV_EXP_2'}) + verifyEqual(testCase, report.invalid.line, [11; 14]) + verifyEqual(testCase, report.unmatched.line, 15) + + % A row with more filled fields than columns is an error. + bad = [tempname '.tsv']; + writeLines(bad, {'rxn kcat source', 'R2 1 brenda extra'}); + verifyError(testCase, @() loadKcatSource(full, bad), 'loadKcatSource:fields') +end + +function [records, header] = rowsOf(model, file) + % The rows and header of a kcat source file, as loadKcatSource reads them. + [~, report] = loadKcatSource(model, file); + records = report.records; + header = report.header; +end + +function writeLines(file, lines) +fid = fopen(file, 'w'); +fprintf(fid, '%s\n', lines{:}); +fclose(fid); +end + +function [full, light, adapter] = buildKcatModels() + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); + model = getGeckoTestModel(); + full = makeEcModel(model, false, adapter); + full = getECfromGEM(full); + light = makeEcModel(model, true, adapter); + light = getECfromGEM(light); +end diff --git a/test/unit_tests/levelComplexTests.m b/test/unit_tests/levelComplexTests.m new file mode 100644 index 00000000..63905d41 --- /dev/null +++ b/test/unit_tests/levelComplexTests.m @@ -0,0 +1,297 @@ +%run this test case with the command +%results = runtests('levelComplexTests.m') + +function tests = levelComplexTests + tests = functiontests(localfunctions); +end + +function testComplexFamiliesGroupIsozymesAndFlagSharedSubunits_tc0262(testCase) + % B is in an isozyme variant with C, so A, B and C are one complex; S is + % in two complexes of equal weight and belongs to none. + model = ecOnly(nan(9, 1), toyRows()); + families = getComplexFamilies(model); + verifyEqual(testCase, sortedComplexes(families), {{'A','B','C'}, {'D','F','S'}, {'E','G','S'}}) + verifyEqual(testCase, families.shared, {'S'}) + [~, b] = ismember('B', model.ec.enzymes); + [~, s] = ismember('S', model.ec.enzymes); + [~, h] = ismember('H', model.ec.enzymes); + verifyEqual(testCase, families.complexes{families.owner(b)}.enzymes(families.complexes{families.owner(b)}.owned), {'A';'B';'C'}) + verifyEqual(testCase, families.owner(s), 0) + verifyEqual(testCase, families.owner(h), 0) +end + +function testComplexFamiliesEnzymeThatWorksAloneIsShared_tc0263(testCase) + rows = toyRows(); + rows(end+1, :) = {'R5', struct('A', 1)}; + families = getComplexFamilies(ecOnly(nan(9, 1), rows)); + verifyTrue(testCase, ismember('A', families.shared)) +end + +function testComplexFamiliesCarrierDoesNotBridgeComplexes_tc0264(testCase) + % B, C, D take carrier S or carrier H (two variants); S also pairs with + % E, like cytochrome c with a dehydrogenase. A single shared protein does + % not merge the two. + rows = {'R1_EXP_1', struct('B',1,'C',1,'D',1,'S',1); ... + 'R1_EXP_2', struct('B',1,'C',1,'D',1,'H',1); ... + 'R2', struct('E',1,'S',1)}; + families = getComplexFamilies(ecOnly(nan(9, 1), rows)); + verifyEqual(testCase, sortedComplexes(families), {{'B','C','D','H','S'}, {'E','S'}}) + verifyTrue(testCase, ismember('S', families.shared)) +end + +function testComplexFamiliesSubunitInTwoComplexesGoesToTheHeavier_tc0265(testCase) + % A, B, C, D is a complex on three reactions; A, B with E, F, G, H on + % one (an assembly step): A and B belong to the first complex. + big = struct('A',1,'B',1,'C',1,'D',1); + rows = {'R1', big; 'R2', big; 'R3', big; ... + 'R4', struct('A',1,'B',1,'E',1,'F',1,'G',1,'H',1)}; + model = ecOnly(nan(9, 1), rows); + families = getComplexFamilies(model); + verifyEmpty(testCase, families.shared) + verifyEqual(testCase, sort(ownedBy(families, model, 'A')), {'A';'B';'C';'D'}) + verifyEqual(testCase, sort(ownedBy(families, model, 'E')), {'E';'F';'G';'H'}) + % with equal weights the two subunits are shared + rows = {'R1', big; 'R2', struct('A',1,'B',1,'E',1,'F',1,'G',1,'H',1)}; + families = getComplexFamilies(ecOnly(nan(9, 1), rows)); + verifyTrue(testCase, all(ismember({'A','B'}, families.shared))) +end + +function testComplexFamiliesWarnWhenVariantsDisagreeOnCopies_tc0266(testCase) + rows = {'R1', struct('A',1,'B',2); 'R2', struct('A',1,'B',3,'C',1)}; + model = ecOnly(nan(9, 1), rows); + verifyWarning(testCase, @() getComplexFamilies(model), 'getComplexFamilies:copiesDisagree') + warning('off', 'getComplexFamilies:copiesDisagree'); + families = getComplexFamilies(model); + warning('on', 'getComplexFamilies:copiesDisagree'); + [~, b] = ismember('B', families.complexes{1}.enzymes); + verifyEqual(testCase, families.complexes{1}.copies(b), 2) +end + +function testLevelComplexConcsMedianScalesByCopies_tc0267(testCase) + % Molar amount per copy: A 1, B 8 / 2 = 4, C 2; the median 2 gives + % A = 2 * 1 copy, B = 2 * 2 copies, C = 2 * 1 copy. + concs = nan(9, 1); + concs(1) = 100; concs(2) = 1600; concs(3) = 100; + model = ecOnly(concs, toyRows()); + [model, result] = levelComplexConcs(model); + verifyEqual(testCase, model.ec.concs(1:3), [200; 800; 100], 'RelTol', 1e-12) + verifyTrue(testCase, isnan(model.ec.concs(9))) + verifyEqual(testCase, sort(result.adjusted), {'A';'B'}) + verifyEmpty(testCase, result.added) +end + +function testLevelComplexConcsMeanIsAvailable_tc0268(testCase) + % Molar amount per copy: A 1, B 4 / 2 = 2, C 6; the mean is 3. + concs = nan(9, 1); + concs(1) = 100; concs(2) = 800; concs(3) = 300; + model = levelComplexConcs(ecOnly(concs, toyRows()), 'statistic', 'mean'); + verifyEqual(testCase, model.ec.concs(1:3), [300; 1200; 150], 'RelTol', 1e-12) + model = levelComplexConcs(ecOnly(concs, toyRows()), 'median'); + verifyEqual(testCase, model.ec.concs(1:3), [200; 800; 100], 'RelTol', 1e-12) +end + +function testLevelComplexConcsSharedSubunitStaysAndMissingOneIsFilled_tc0269(testCase) + concs = nan(9, 1); + concs(4) = 100; % D + concs(6) = 900; % S, shared between two complexes + [model, result] = levelComplexConcs(ecOnly(concs, toyRows())); + verifyEqual(testCase, model.ec.concs([4 5 6]), [100; 100; 900]) + verifyEqual(testCase, result.shared, {'S'}) + verifyEqual(testCase, result.added, {'F'}) + % filling can be switched off + model = levelComplexConcs(ecOnly(concs, toyRows()), 'fillMissing', false); + verifyTrue(testCase, isnan(model.ec.concs(5))) + verifyEqual(testCase, model.ec.concs(6), 900) +end + +function testLevelComplexConcsFillsSubunitOfIsozymeVariant_tc0270(testCase) + % C is in the second variant and is not measured: it gets the + % median per copy (A 1, B 4 / 2 = 2: 1.5) at its molecular weight. + concs = nan(9, 1); + concs(1) = 100; concs(2) = 800; + [model, result] = levelComplexConcs(ecOnly(concs, toyRows())); + verifyEqual(testCase, model.ec.concs(1:3), [150; 600; 75], 'RelTol', 1e-12) + verifyEqual(testCase, result.added, {'C'}) +end + +function testLevelComplexConcsReportsComplexWithoutMeasurement_tc0271(testCase) + concs = nan(9, 1); + concs(1) = 100; % complex A, B, C is measured + [model, result] = levelComplexConcs(ecOnly(concs, toyRows())); + verifyEqual(testCase, result.skipped, {{'D','F','S'}; {'E','G','S'}}) + verifyTrue(testCase, all(isnan(model.ec.concs(4:9)))) +end + +function testLevelComplexConcsRejectsUnknownStatistic_tc0272(testCase) + model = ecOnly(nan(9, 1), toyRows()); + verifyError(testCase, @() levelComplexConcs(model, 'statistic', 'max'), 'levelComplexConcs:statistic') +end + +function testFlexibilizePerComplexRaisesSubunitsByTheSameFactor_tc0273(testCase) + adapter = getAdapter(); + % Without perComplex the limiting subunit alone is raised + [model, flexEnz] = flexibilizeEnzConcs(complexToy([1 3], [1 3]), 2, [], [], adapter, false); + verifyEqual(testCase, flexEnz.uniprotIDs, {'X1'}) + verifyEqual(testCase, usageUb(model, 'X2'), 3) + % With perComplex both are raised by one factor + [model, flexEnz] = flexibilizeEnzConcs(complexToy([1 3], [1 3]), 'expGrowth', 2, ... + 'modelAdapter', adapter, 'verbose', false, 'perComplex', true); + verifyEqual(testCase, sort(flexEnz.uniprotIDs), {'X1';'X2'}) + [~, order] = ismember({'X1';'X2'}, flexEnz.uniprotIDs); + verifyEqual(testCase, flexEnz.flexConcs(order), [1.995; 5.985], 'RelTol', 1e-6) + verifyEqual(testCase, usageUb(model, 'X1') / 1, usageUb(model, 'X2') / 3, 'RelTol', 1e-9) + sol = solveLP(model); + verifyEqual(testCase, sol.f, 2, 'RelTol', 5e-3) + % a cap is never lowered below its measurement + verifyGreaterThanOrEqual(testCase, usageUb(model, 'X1'), 1) + verifyGreaterThanOrEqual(testCase, usageUb(model, 'X2'), 3) + verifyEqual(testCase, flexEnz.ratioIncr, flexEnz.flexConcs ./ flexEnz.oldConcs) +end + +function testFlexibilizePerComplexKeepsLevelledComplexLevelled_tc0274(testCase) + % Both subunits capped at 1 bind together: no single subunit shows a gain + adapter = getAdapter(); + [model, flexEnz] = flexibilizeEnzConcs(complexToy([1 1], [1 1]), 'expGrowth', 2, ... + 'modelAdapter', adapter, 'verbose', false, 'perComplex', true); + verifyEqual(testCase, usageUb(model, 'X1'), usageUb(model, 'X2'), 'RelTol', 1e-9) + verifyEqual(testCase, sort(flexEnz.uniprotIDs), {'X1';'X2'}) + sol = solveLP(model); + verifyEqual(testCase, sol.f, 2, 'RelTol', 5e-3) +end + +function testFlexibilizePerComplexFalseIsTheDefault_tc0275(testCase) + adapter = getAdapter(); + [m0, f0] = flexibilizeEnzConcs(complexToy([1 3], [1 3]), 'expGrowth', 2, 'modelAdapter', adapter, 'verbose', false); + [m1, f1] = flexibilizeEnzConcs(complexToy([1 3], [1 3]), 'expGrowth', 2, 'modelAdapter', adapter, 'verbose', false, 'perComplex', false); + verifyEqual(testCase, m1, m0) + verifyEqual(testCase, f1, f0) + verifyEqual(testCase, f0.uniprotIDs, {'X1'}) +end + +function testFlexibilizePerComplexDoesNotPickComplexForPoolPrice_tc0276(testCase) + % A -> B by the complex X1, X2, X3 and B -> P by the single enzyme E, + % with a protein pool that binds. At flux 1 every subunit uses 80% of a + % 1.25 cap, E uses all of its cap of 1. Of the enzymes, E alone limits. + adapter = getAdapter(); + [model, flexEnz] = flexibilizeEnzConcs(seriesToy(), 'expGrowth', 1.1, 'modelAdapter', adapter, ... + 'verbose', false, 'perComplex', true); + verifyEqual(testCase, flexEnz.uniprotIDs(:), {'prot_pool';'E'}) + verifyEqual(testCase, usageUb(model, 'E'), 1.09725, 'RelTol', 1e-4) + for e = {'X1','X2','X3'} + verifyEqual(testCase, usageUb(model, e{1}), 1.25, 'RelTol', 1e-9) + end + sol = solveLP(model); + verifyGreaterThanOrEqual(testCase, sol.f, 1.1 * 0.9975 - 1e-9) +end + +% ---- helpers + +function adapter = getAdapter() + adapter = ModelAdapterManager.getAdapter(fullfile(findGECKOroot,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); +end + +function rows = toyRows() + rows = {'R1_EXP_1', struct('A',1,'B',2); ... + 'R1_EXP_2', struct('A',1,'B',2,'C',1); ... % isozyme variant: same complex + 'R2', struct('D',1,'F',1,'S',1); ... + 'R3', struct('E',1,'G',1,'S',1); ... % S is shared with the complex of R2 + 'R4', struct('H',1)}; % a single enzyme: not a complex +end + +function model = ecOnly(concs, rows) + % A model that carries nothing but the ec data: rows is {rxn, struct(enzyme, copies)} + enzymes = {'A';'B';'C';'D';'F';'S';'E';'G';'H'}; + mw = [100; 200; 50; 100; 100; 100; 100; 100; 100]; + mat = zeros(size(rows, 1), numel(enzymes)); + for r = 1:size(rows, 1) + names = fieldnames(rows{r, 2}); + for n = 1:numel(names) + mat(r, strcmp(enzymes, names{n})) = rows{r, 2}.(names{n}); + end + end + model.ec.rxns = rows(:, 1); + model.ec.genes = strcat('g_', enzymes); + model.ec.enzymes = enzymes; + model.ec.mw = mw; + model.ec.concs = concs(:); + model.ec.rxnEnzMat = sparse(mat); +end + +function sets = sortedComplexes(families) + sets = cellfun(@(c) sort(c.enzymes(:))', families.complexes, 'UniformOutput', false); + [~, order] = sort(cellfun(@(c) strjoin(c, ''), sets, 'UniformOutput', false)); + sets = sets(order)'; +end + +function names = ownedBy(families, model, enzyme) + [~, e] = ismember(enzyme, model.ec.enzymes); + c = families.complexes{families.owner(e)}; + names = c.enzymes(c.owned); +end + +function ub = usageUb(model, enzyme) + ub = model.ub(strcmp(model.rxns, ['usage_prot_' enzyme])); +end + +function model = complexToy(concs, ubs) + % A -> B is catalysed by the complex X1 + X2; growth (R4) equals the flux. + model = buildLP({'A_e';'A_c';'B_c';'prot_pool';'prot_X1';'prot_X2'}, ... + {'EX_A', {'A_e',-1}, -1000, 0; ... + 'TR_A', {'A_e',-1,'A_c',1}, 0, 1000; ... + 'R_AB', {'A_c',-1,'B_c',1,'prot_X1',-1,'prot_X2',-1}, 0, 1000; ... + 'R4', {'B_c',-1}, 0, 1000; ... + 'prot_pool_exchange', {'prot_pool',1}, 0, 1000; ... + 'usage_prot_X1', {'prot_pool',-1,'prot_X1',1}, 0, ubs(1); ... + 'usage_prot_X2', {'prot_pool',-1,'prot_X2',1}, 0, ubs(2)}); + model.ec.enzymes = {'X1';'X2'}; + model.ec.rxns = {'R_AB'}; + model.ec.genes = {'g_X1';'g_X2'}; + model.ec.mw = [100; 100]; + model.ec.concs = concs(:); + model.ec.rxnEnzMat = sparse([1 1]); +end + +function model = seriesToy() + % A -> B by the complex X1, X2, X3, B -> P by the enzyme E; the pool + % holds exactly 4 mg. + model = buildLP({'A';'B';'P';'prot_pool';'prot_X1';'prot_X2';'prot_X3';'prot_E'}, ... + {'EX_A', {'A',1}, 0, 1000; ... + 'R1', {'A',-1,'B',1,'prot_X1',-1,'prot_X2',-1,'prot_X3',-1}, 0, 1000; ... + 'R2', {'B',-1,'P',1,'prot_E',-1}, 0, 1000; ... + 'R4', {'P',-1}, 0, 1000; ... + 'prot_pool_exchange', {'prot_pool',1}, 0, 4; ... + 'usage_prot_X1', {'prot_pool',-1,'prot_X1',1}, 0, 1.25; ... + 'usage_prot_X2', {'prot_pool',-1,'prot_X2',1}, 0, 1.25; ... + 'usage_prot_X3', {'prot_pool',-1,'prot_X3',1}, 0, 1.25; ... + 'usage_prot_E', {'prot_pool',-1,'prot_E',1}, 0, 1}); + model.ec.enzymes = {'X1';'X2';'X3';'E'}; + model.ec.rxns = {'R1';'R2'}; + model.ec.genes = {'g1';'g2';'g3';'gE'}; + model.ec.mw = [100; 100; 100; 100]; + model.ec.concs = [1.25; 1.25; 1.25; 1]; + model.ec.rxnEnzMat = sparse([1 1 1 0; 0 0 0 1]); +end + +function model = buildLP(mets, rxnSpec) + % rxnSpec rows: id, {metabolite, coefficient, ...}, lb, ub. The reaction + % named R4 is the objective, which is the biomass reaction of the adapter. + nR = size(rxnSpec, 1); + S = zeros(numel(mets), nR); + for r = 1:nR + entries = rxnSpec{r, 2}; + for n = 1:2:numel(entries) + S(strcmp(mets, entries{n}), r) = entries{n+1}; + end + end + model.id = 'toy'; + model.mets = mets; + model.metNames = mets; + model.rxns = rxnSpec(:, 1); + model.rxnNames = rxnSpec(:, 1); + model.S = sparse(S); + model.lb = cell2mat(rxnSpec(:, 3)); + model.ub = cell2mat(rxnSpec(:, 4)); + model.c = double(strcmp(model.rxns, 'R4')); + model.b = zeros(numel(mets), 1); + model.rev = double(model.lb < 0); +end diff --git a/test/unit_tests/metSmilesCacheTests.m b/test/unit_tests/metSmilesCacheTests.m new file mode 100644 index 00000000..97391884 --- /dev/null +++ b/test/unit_tests/metSmilesCacheTests.m @@ -0,0 +1,39 @@ +%run this test case with the command +%results = runtests('metSmilesCacheTests.m') + +function tests = metSmilesCacheTests + tests = functiontests(localfunctions); +end + +function testFindMetSmilesUsesLastRowOfDuplicateName_tc0407(testCase) + adapter = cacheAdapter(testCase, sprintf('a\tFIRST\nb\tCCO\na\tLAST\n')); + model = struct('metNames', {{'a';'b';'a'}}); + [~, out] = evalc('findMetSmiles(model, ''modelAdapter'', adapter, ''verbose'', false)'); + verifyEqual(testCase, out.metSmiles, {'LAST';'CCO';'LAST'}) +end + +function testFindMetSmilesSkipsEmptyNameWithWarning_tc0408(testCase) + adapter = cacheAdapter(testCase, sprintf('a\tCCO\n')); + model = struct('metNames', {{'a';'';'prot_P1'}}); + verifyWarning(testCase, @() quietFind(model, adapter), 'findMetSmiles:emptyName') + warning('off', 'findMetSmiles:emptyName') + cleanup = onCleanup(@() warning('on', 'findMetSmiles:emptyName')); %#ok + [~, out] = evalc('findMetSmiles(model, ''modelAdapter'', adapter, ''verbose'', false)'); + verifyEqual(testCase, out.metSmiles, {'CCO';'';''}) +end + +function quietFind(model, adapter) + evalc('findMetSmiles(model, ''modelAdapter'', adapter, ''verbose'', false)'); +end + +function adapter = cacheAdapter(testCase, cacheText) + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); + folder = tempname(); + mkdir(fullfile(folder, 'data')); + testCase.addTeardown(@() rmdir(folder, 's')) + fid = fopen(fullfile(folder, 'data', 'smilesDB.tsv'), 'w'); + fprintf(fid, '%s', cacheText); + fclose(fid); + adapter.params.path = folder; +end diff --git a/test/unit_tests/parityDecisionTests.m b/test/unit_tests/parityDecisionTests.m new file mode 100644 index 00000000..081c4cca --- /dev/null +++ b/test/unit_tests/parityDecisionTests.m @@ -0,0 +1,119 @@ +%run this test case with the command +%results = runtests('parityDecisionTests.m') + +function tests = parityDecisionTests + tests = functiontests(localfunctions); +end + +function testMergeKcatsDefaultTopOriginLimitIs4_tc0240(testCase) + % A BRENDA match of origin 5 (specific activity, correct organism) ranks + % after DLKcat by default and above it with topOriginLimit 6. + [fuzzy, dlkcat] = originFiveLists(); + tiers = {'database_top', 'dlkcat', 'database_bottom'}; + merged = mergeKcats({fuzzy, dlkcat}, tiers); + verifyEqual(testCase, merged.kcats(strcmp(merged.rxns, 'R1')), 50) + merged = mergeKcats({fuzzy, dlkcat}, tiers, 'topOriginLimit', 4); + verifyEqual(testCase, merged.kcats(strcmp(merged.rxns, 'R1')), 50) + merged = mergeKcats({fuzzy, dlkcat}, tiers, 'topOriginLimit', 6); + verifyEqual(testCase, merged.kcats(strcmp(merged.rxns, 'R1')), 5) +end + +function testMergeDLKcatAndFuzzyKcatsDefaultTopOriginLimitIs4_tc0241(testCase) + [fuzzy, dlkcat] = originFiveLists(); + merged = mergeDLKcatAndFuzzyKcats(dlkcat, fuzzy); + verifyEqual(testCase, merged.kcats(strcmp(merged.rxns, 'R1')), 50) + merged = mergeDLKcatAndFuzzyKcats(dlkcat, fuzzy, 'topOriginLimit', 6); + verifyEqual(testCase, merged.kcats(strcmp(merged.rxns, 'R1')), 5) +end + +function testFindECInDBSingleGeneDropsWildcardParent_tc0242(testCase) + % One gene whose protein carries '1.1.1.4 1.1.1.- 1.1.1.303' keeps the + % two specific codes and loses the wildcard of the same prefix. + geneHashMap = containers.Map({'G1'}, {1}); + geneIndex = {1}; + DBecNum = {'1.1.1.4 1.1.1.- 1.1.1.303'}; + DBMW = 10000; + EC = findECInDB({'G1'}, DBecNum, DBMW, geneIndex, geneHashMap); + verifyEqual(testCase, EC, '1.1.1.4;1.1.1.303') + % A wildcard without a specific code of its prefix stays + DBecNum = {'1.1.1.- 2.2.2.2'}; + EC = findECInDB({'G1'}, DBecNum, DBMW, geneIndex, geneHashMap); + verifyEqual(testCase, EC, '1.1.1.-;2.2.2.2') +end + +function testFindECInDBSingleGeneShortCodesAndTrailingSpace_tc0243(testCase) + % A code with fewer than four levels is neither the wildcard parent nor + % the child of a four-level code, and a trailing space leaves no empty code. + geneHashMap = containers.Map({'G1'}, {1}); + geneIndex = {1}; + DBMW = 10000; + EC = findECInDB({'G1'}, {'1.1.1 1.1.1.4'}, DBMW, geneIndex, geneHashMap); + verifyEqual(testCase, EC, '1.1.1;1.1.1.4') + EC = findECInDB({'G1'}, {'1.1.1.4 '}, DBMW, geneIndex, geneHashMap); + verifyEqual(testCase, EC, '1.1.1.4') +end + +function testFindECInDBComplexDropsWildcardParent_tc0244(testCase) + % The shared EC set of an enzyme complex loses a wildcard code next to a + % specific code of its prefix, as the set of a single gene does. + DBMW = [10000; 20000; 30000]; + geneHashMap = containers.Map({'G1','G2','G3'}, {1,2,3}); + geneIndex = {1; 2; 3}; + EC = findECInDB({'G1','G2'}, {'1.1.1.4 1.1.1.-'; '1.1.1.4 1.1.1.-'; ''}, DBMW, geneIndex, geneHashMap); + verifyEqual(testCase, EC, '1.1.1.4') + % A wildcard that only the union carries is dropped too + EC = findECInDB({'G1','G2','G3'}, {'1.1.1.4'; '1.1.1.- 2.2.2.2'; '5.5.5.5'}, DBMW, geneIndex, geneHashMap); + verifyEqual(testCase, EC, '1.1.1.4;2.2.2.2;5.5.5.5') + % A wildcard shared by every gene stays, as nothing more specific exists + EC = findECInDB({'G1','G2'}, {'1.1.1.-'; '1.1.1.-'; ''}, DBMW, geneIndex, geneHashMap); + verifyEqual(testCase, EC, '1.1.1.-') +end + +function testFindECInDBGeneWithoutECIsLeftOut_tc0245(testCase) + % A gene without an EC number does not change the codes of the others: + % the complex is treated as the genes that have codes, in either order. + DBMW = [10000; 20000]; + geneHashMap = containers.Map({'G1','G2'}, {1,2}); + geneIndex = {1; 2}; + EC = findECInDB({'G1','G2'}, {'1.1.1.4 1.1.1.-'; ''}, DBMW, geneIndex, geneHashMap); + verifyEqual(testCase, EC, '1.1.1.4') + EC = findECInDB({'G1','G2'}, {''; '1.1.1.4 1.1.1.-'}, DBMW, geneIndex, geneHashMap); + verifyEqual(testCase, EC, '1.1.1.4') + % No gene has a code + EC = findECInDB({'G1','G2'}, {''; ''}, DBMW, geneIndex, geneHashMap); + verifyEqual(testCase, EC, '') + % A gene missing from the database is left out as well + geneHashMap = containers.Map({'G2'}, {2}); + geneIndex = {[]; 2}; + EC = findECInDB({'G1','G2'}, {''; '1.1.1.4 1.1.1.-'}, DBMW, geneIndex, geneHashMap); + verifyEqual(testCase, EC, '1.1.1.4') +end + +function testFindECInDBSplitsCodesOnSemicolons_tc0246(testCase) + % A database cell joins codes with white space, with '; ' or with ';' alone; + % each is read as separate codes. + DBMW = 10000; + geneHashMap = containers.Map({'G1'}, {1}); + geneIndex = {1}; + cells = {'1.1.1.1 2.2.2.2', '1.1.1.1; 2.2.2.2;', '1.1.1.1;2.2.2.2', ' 1.1.1.1;;2.2.2.2 '}; + for i = 1:numel(cells) + EC = findECInDB({'G1'}, cells(i), DBMW, geneIndex, geneHashMap); + verifyEqual(testCase, EC, '1.1.1.1;2.2.2.2') + end +end + +function [fuzzy, dlkcat] = originFiveLists() + fuzzy.rxns = {'R1'}; + fuzzy.kcats = 5; + fuzzy.genes = {{}}; + fuzzy.substrates = {{}}; + fuzzy.eccodes = {'1.1.1.1'}; + fuzzy.wildcardLvl = 0; + fuzzy.origin = 5; + fuzzy.source = 'brenda'; + dlkcat.rxns = {'R1'}; + dlkcat.kcats = 50; + dlkcat.genes = {'G1'}; + dlkcat.substrates = {'m1'}; + dlkcat.source = 'DLKcat'; +end diff --git a/test/unit_tests/parityRound3Tests.m b/test/unit_tests/parityRound3Tests.m new file mode 100644 index 00000000..fa9edb33 --- /dev/null +++ b/test/unit_tests/parityRound3Tests.m @@ -0,0 +1,319 @@ +%run this test case with the command +%results = runtests('parityRound3Tests.m') + +function tests = parityRound3Tests + tests = functiontests(localfunctions); +end + +function testApplyKcatConstraintsAllZeroClearsFullModel_tc0250(testCase) + % With every kcat 0 the enzyme constraints of a full ecModel are removed + % and no new ones are written. A light ecModel is returned unchanged. + adapter = getAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + ecModel.ec.kcat(:) = 10; + ecModel = applyKcatConstraints(ecModel); + protMets = startsWith(ecModel.mets, 'prot_') & ~strcmp(ecModel.mets, 'prot_pool'); + metabolic = ~startsWith(ecModel.rxns, 'usage_prot_') & ~strcmp(ecModel.rxns, 'prot_pool_exchange'); + verifyGreaterThan(testCase, nnz(ecModel.S(protMets, metabolic)), 0) + ecModel.ec.kcat(:) = 0; + cleared = applyKcatConstraints(ecModel); + verifyEqual(testCase, nnz(cleared.S(protMets, metabolic)), 0) + % the usage reactions and the pool exchange keep their fixed entries + verifyEqual(testCase, cleared.S(:, ~metabolic), ecModel.S(:, ~metabolic)) +end + +function testApplyKcatConstraintsAllZeroClearsLightModel_tc0250light(testCase) + % With every kcat 0 the pool coefficients of a light ecModel are cleared, + % as the enzyme constraints of a full ecModel are. + adapter = getAdapter(); + lecModel = makeEcModel(getGeckoTestModel(), true, adapter); + lecModel.ec.kcat(:) = 10; + lecModel = applyKcatConstraints(lecModel); + poolRow = strcmp(lecModel.mets, 'prot_pool'); + verifyGreaterThan(testCase, nnz(lecModel.S(poolRow, :)), 1) + lecModel.ec.kcat(:) = 0; + cleared = applyKcatConstraints(lecModel); + poolRow = strcmp(cleared.mets, 'prot_pool'); + metabolic = ~strcmp(cleared.rxns, 'prot_pool_exchange'); + verifyEqual(testCase, nnz(cleared.S(poolRow, metabolic)), 0) + verifyEqual(testCase, cleared.S(:, ~metabolic), lecModel.S(:, ~metabolic)) +end + +function testSensitivityTuningStopsOnGrowthBelowTolerance_tc0251(testCase) + % The solver reports a growth of 1 in the first iteration and 1 + 5e-10 in + % the second: the gain is below 1e-9, so the loop stops after the second + % iteration (3 solves with the one before the loop). An exact-equality + % loop would go on until two growths are identical (4 solves). + [ecModel, tuneAdapter] = tuningModel(); + cleanup = shadowSolveLP('growth', [1 1 1+5e-10]); %#ok + tunedModel = sensitivityTuning(ecModel, 'desiredGrowthRate', 50, ... + 'modelAdapter', tuneAdapter, 'protToIgnore', {'P4'}, 'verbose', false); + verifyEqual(testCase, getappdata(0, 'gecko_test_solvelp_count'), 3) + r5 = tunedModel.ec.kcat(strcmp(tunedModel.ec.rxns, 'R5')); + verifyGreaterThan(testCase, r5, 200) +end + +function testSensitivityTuningEndsWhenTheLPBecomesInfeasible_tc0254(testCase) + % The third solve (the second iteration) has no solution: RAVEN returns + % an empty objective value. The loop ends with a warning and returns + % what was tuned in the first iteration. + [ecModel, tuneAdapter] = tuningModel(); + cleanup = shadowSolveLP('infeasibleFrom', 3); %#ok + out = evalc(['tunedModel = sensitivityTuning(ecModel, ''desiredGrowthRate'', 50, ' ... + '''modelAdapter'', tuneAdapter, ''protToIgnore'', {''P4''}, ''verbose'', false);']); + verifyTrue(testCase, contains(out, 'no feasible solution')) + verifyEqual(testCase, getappdata(0, 'gecko_test_solvelp_count'), 3) + r5 = tunedModel.ec.kcat(strcmp(tunedModel.ec.rxns, 'R5')); + verifyGreaterThan(testCase, r5, 200) +end + +function testSensitivityTuningStopsWhenNothingCarriesFlux_tc0253(testCase) + % R5, the growth reaction, is blocked: growth is 0 from the start and no + % usage reaction carries flux. The loop ends with a warning instead of + % tuning an arbitrary reaction or failing, and no kcat changes. + adapter = getAdapter(); + model = loadConventionalGEM('modelAdapter', adapter); + for id = {'R2', 'R4', 'R5'} + idx = strcmp(model.rxns, id{1}); + model.lb(idx) = 0; model.ub(idx) = 0; + end + ecModel = makeEcModel(model, false, adapter); + ecModel = getECfromGEM(ecModel); + ecModel.ec.kcat(strcmp(ecModel.ec.rxns, 'R3')) = 0.05; + ecModel = applyKcatConstraints(ecModel); + ecModel = setProtPoolSize(ecModel, [], [], [], adapter); + tuneAdapter = adapter; + tuneAdapter.params.bioRxn = 'R5'; + [tunedModel, tunedKcats] = sensitivityTuning(ecModel, 'desiredGrowthRate', 50, ... + 'modelAdapter', tuneAdapter, 'verbose', false); + verifyEqual(testCase, tunedModel.ec.kcat, ecModel.ec.kcat) + verifyEmpty(testCase, tunedKcats.rxns) +end + +function testGetKcatAcrossIsozymesUsesPositiveSiblingsOnly_tc0252(testCase) + % Only isozymes with a kcat above 0 enter the mean: a negative or NaN + % sibling does not fill a kcat of 0. + adapter = getAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + ecModel.ec.kcat(:) = 0; + ecModel.ec.kcat(strcmp(ecModel.ec.rxns, 'R3')) = 8; + % R2: a zero next to a negative sibling is not filled + ecModel.ec.kcat(strcmp(ecModel.ec.rxns, 'R2_EXP_2')) = -3; + % R2_REV: a zero next to a NaN sibling is not filled + ecModel.ec.kcat(strcmp(ecModel.ec.rxns, 'R2_REV_EXP_2')) = NaN; + out = getKcatAcrossIsozymes(ecModel); + verifyEqual(testCase, out.ec.kcat(strcmp(out.ec.rxns, 'R2_EXP_1')), 0) + verifyEqual(testCase, out.ec.kcat(strcmp(out.ec.rxns, 'R2_REV_EXP_1')), 0) + % a positive sibling fills the zero (control: the same before and after) + ecModel.ec.kcat(strcmp(ecModel.ec.rxns, 'R2_EXP_2')) = 6; + out = getKcatAcrossIsozymes(ecModel); + j = strcmp(out.ec.rxns, 'R2_EXP_1'); + verifyEqual(testCase, out.ec.kcat(j), 6) + verifyEqual(testCase, out.ec.source{j}, 'isozymes') + % a NaN sibling next to a positive one is left out of the mean: three + % isozymes of R2 with kcats 0, NaN and 6 give 6 to the first + ecModel.ec.kcat(:) = 0; + ecModel.ec.rxns{strcmp(ecModel.ec.rxns, 'R3')} = 'R2_EXP_3'; + ecModel.ec.kcat(strcmp(ecModel.ec.rxns, 'R2_EXP_2')) = NaN; + ecModel.ec.kcat(strcmp(ecModel.ec.rxns, 'R2_EXP_3')) = 6; + out = getKcatAcrossIsozymes(ecModel); + j = strcmp(out.ec.rxns, 'R2_EXP_1'); + verifyEqual(testCase, out.ec.kcat(j), 6) + verifyEqual(testCase, out.ec.source{j}, 'isozymes') + verifyTrue(testCase, isnan(out.ec.kcat(strcmp(out.ec.rxns, 'R2_EXP_2')))) +end + +function testSigmaFitterReturnsStartOfGrowthPlateau_tc0255(testCase) +% The growth target is above what the uptake-limited model reaches, so growth +% is flat from sigma 0.06 on. GLPK returns the plateau growth with rounding +% noise (49.999999999999986 at sigma 0.06, 50 at sigma 1). The fitted sigma is +% the start of the plateau, 0.06, whatever the noise, and the same on Gurobi. +previous = getpref('RAVEN', 'solver', 'glpk'); +restore = onCleanup(@() setRavenSolver(previous)); %#ok +setRavenSolver('glpk'); +sigmaGlpk = plateauSigma(); +verifyEqual(testCase, sigmaGlpk, 0.06, 'AbsTol', 1e-12) +hasGurobi = false; +if exist('gurobi', 'file') + try + setRavenSolver('gurobi'); + hasGurobi = true; + catch + end +end +assumeTrue(testCase, hasGurobi, 'Gurobi is not available') +verifyEqual(testCase, plateauSigma(), sigmaGlpk, 'AbsTol', 1e-12) +end + +function testGetStandardKcatSubSystemNamesIgnoreCase_tc0256(testCase) +% R3 is in 'Alpha', R5 in 'alpha', the entries of R2 in 'Beta'. The names +% 'Alpha' and 'alpha' are one subSystem, so R6 ('ALPHA') gets the median of +% R3 and R5 (5) and not the model-wide median (100). +[ecModel, adapter] = standardKcatModel(struct('R5', 'alpha', 'R2', 'Beta', 'R6', 'ALPHA')); +ecModel = getStandardKcat(ecModel, 'modelAdapter', adapter, 'threshold', 2); +verifyEqual(testCase, ecModel.ec.kcat(strcmp(ecModel.ec.rxns, 'R6')), 5) +end + +function testGetStandardKcatReactionWithoutSubSystem_tc0257(testCase) +% R7 has an empty subSystem while the other reactions have one: it gets the +% model-wide median kcat (100), R6 the one of its subSystem 'Alpha' (5). +[ecModel, adapter] = standardKcatModel(struct('R2', 'Beta', 'R7', '')); +ecModel = getStandardKcat(ecModel, 'modelAdapter', adapter, 'threshold', 2); +verifyEqual(testCase, ecModel.ec.kcat(strcmp(ecModel.ec.rxns, 'R7')), 100) +verifyEqual(testCase, ecModel.ec.kcat(strcmp(ecModel.ec.rxns, 'R6')), 5) +end + +function testGetSubsetEcModelKeepsEverythingForTheFullModel_tc0258(testCase) +% The context model is the conventional model, so no gene is removed and the +% ecModel is returned as it is, for the full and the light ecModel. The +% reaction identifiers of the light ecModel have a prefix; they are matched +% by the reaction they stand for, so they are not all removed. +adapter = getAdapter(); +model = loadConventionalGEM('modelAdapter', adapter); +for light = [false true] + bigEcModel = makeEcModel(model, light, adapter); + smallEcModel = getSubsetEcModel(bigEcModel, model); + verifyEqual(testCase, smallEcModel, bigEcModel) + verifyNotEmpty(testCase, smallEcModel.ec.rxns) +end +end + +function testGetSubsetEcModelLightDropsEcEntriesOfRemovedRxns_tc0259(testCase) +% The context model lacks R2: the light ecModel loses the entry 001_R2 of +% its ec structure and keeps the others. +adapter = getAdapter(); +model = loadConventionalGEM('modelAdapter', adapter); +small = removeReactions(model, {'R2'}, 'removeUnusedMets', true, 'removeUnusedGenes', true); +bigEcModel = makeEcModel(model, true, adapter); +smallEcModel = getSubsetEcModel(bigEcModel, small); +verifyFalse(testCase, ismember('001_R2', smallEcModel.ec.rxns)) +verifyTrue(testCase, all(ismember({'001_R3', '001_R5'}, smallEcModel.ec.rxns))) +verifyEqual(testCase, size(smallEcModel.ec.rxnEnzMat, 1), numel(smallEcModel.ec.rxns)) +end + +function [ecModel, adapter] = standardKcatModel(subSystems) +% ecTestGEM with R6 and R7 added (no genes) and the subSystems given as a +% struct of reaction id to name (an empty name is no subSystem); reactions +% not listed are in 'Alpha'. The kcats +% are R3 2, R5 8, the entries of R2 100. +adapter = getAdapter(); +model = loadConventionalGEM('modelAdapter', adapter); +rxnsToAdd.rxns = {'R6'; 'R7'}; +rxnsToAdd.equations = {'m1[c] => m2[c]'; 'm1[c] => m2[c]'}; +rxnsToAdd.grRules = {''; ''}; +model = addRxns(model, rxnsToAdd, 3); +model.subSystems = cell(numel(model.rxns), 1); +for i = 1:numel(model.rxns) + name = 'Alpha'; + if isfield(subSystems, model.rxns{i}) + name = subSystems.(model.rxns{i}); + end + if isempty(name) + model.subSystems{i} = {}; + else + model.subSystems{i} = {name}; + end +end +ecModel = makeEcModel(model, false, adapter); +ecModel = getECfromGEM(ecModel); +ecModel.ec.kcat(:) = 100; +ecModel.ec.kcat(strcmp(ecModel.ec.rxns, 'R3')) = 2; +ecModel.ec.kcat(strcmp(ecModel.ec.rxns, 'R5')) = 8; +ecModel.ec.source(:) = {'manual'}; +end + +function sigma = plateauSigma() +adapter = getAdapter(); +model = loadConventionalGEM('modelAdapter', adapter); +model.lb(strcmp(model.rxns, 'S1')) = -50; +for id = {'R2', 'R4'} + idx = strcmp(model.rxns, id{1}); + model.lb(idx) = 0; model.ub(idx) = 0; +end +ecModel = makeEcModel(model, false, adapter); +ecModel = getECfromGEM(ecModel); +kcats = struct('R3', 5, 'R5', 200); +for id = fieldnames(kcats)' + j = strcmp(ecModel.ec.rxns, id{1}); + ecModel.ec.kcat(j) = kcats.(id{1}); + ecModel.ec.source{j} = 'manual'; +end +ecModel.c = double(strcmp(ecModel.rxns, 'R5')); +ecModel = applyKcatConstraints(ecModel); +ecModel = setProtPoolSize(ecModel, [], [], [], adapter); +[~, sigma] = sigmaFitter(ecModel, 'growthRate', 100, 'Ptot', 0.5, 'f', 4, ... + 'makePlot', false, 'modelAdapter', adapter); +end + +function [ecModel, tuneAdapter] = tuningModel() +% R3 limits growth, its enzyme P4 is ignored by the tests, so tuning raises R5. +adapter = getAdapter(); +model = loadConventionalGEM('modelAdapter', adapter); +for id = {'R2', 'R4'} + idx = strcmp(model.rxns, id{1}); + model.lb(idx) = 0; model.ub(idx) = 0; +end +ecModel = makeEcModel(model, false, adapter); +ecModel = getECfromGEM(ecModel); +kcats = struct('R3', 0.05, 'R5', 200); +for id = fieldnames(kcats)' + j = strcmp(ecModel.ec.rxns, id{1}); + ecModel.ec.kcat(j) = kcats.(id{1}); + ecModel.ec.source{j} = 'manual'; +end +ecModel = applyKcatConstraints(ecModel); +ecModel = setProtPoolSize(ecModel, [], [], [], adapter); +tuneAdapter = adapter; +tuneAdapter.params.bioRxn = 'R5'; +end + +function cleanup = shadowSolveLP(mode, values) +% Puts a solveLP on the path that calls RAVEN's and then reports the growth +% of solve number n as values(min(n, end)) ('growth'), or no solution from +% solve number values on ('infeasibleFrom'). The number of solves is kept in +% the root appdata gecko_test_solvelp_count. The path is restored when the +% returned object is cleared. +setappdata(0, 'gecko_test_solvelp_real', @solveLP); +setappdata(0, 'gecko_test_solvelp_count', 0); +setappdata(0, 'gecko_test_solvelp_mode', mode); +setappdata(0, 'gecko_test_solvelp_values', values); +stubDir = tempname; +mkdir(stubDir); +fid = fopen(fullfile(stubDir, 'solveLP.m'), 'w'); +fprintf(fid, '%s\n', ... + 'function [res,hs] = solveLP(varargin)', ... + 'n = getappdata(0,''gecko_test_solvelp_count'') + 1;', ... + 'setappdata(0,''gecko_test_solvelp_count'',n);', ... + 'real = getappdata(0,''gecko_test_solvelp_real'');', ... + 'mode = getappdata(0,''gecko_test_solvelp_mode'');', ... + 'values = getappdata(0,''gecko_test_solvelp_values'');', ... + '[res,hs] = real(varargin{:});', ... + 'switch mode', ... + ' case ''growth''', ... + ' res.f = values(min(n,numel(values)));', ... + ' case ''infeasibleFrom''', ... + ' if n >= values', ... + ' res.f = [];', ... + ' res.x = [];', ... + ' end', ... + 'end', ... + 'end'); +fclose(fid); +addpath(stubDir, '-begin'); +cleanup = onCleanup(@() removeShadow(stubDir)); +end + +function removeShadow(stubDir) +rmpath(stubDir); +rmdir(stubDir, 's'); +for name = {'real', 'mode', 'values'} + if isappdata(0, ['gecko_test_solvelp_' name{1}]) + rmappdata(0, ['gecko_test_solvelp_' name{1}]); + end +end +end + +function adapter = getAdapter() +geckoPath = findGECKOroot; +adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); +end diff --git a/test/unit_tests/parityRound5G3Tests.m b/test/unit_tests/parityRound5G3Tests.m new file mode 100644 index 00000000..a37fd604 --- /dev/null +++ b/test/unit_tests/parityRound5G3Tests.m @@ -0,0 +1,242 @@ +%run this test case with the command +%results = runtests('parityRound5G3Tests.m') + +function tests = parityRound5G3Tests + tests = functiontests(localfunctions); +end + +function testAddNewRxnsToECWithoutNewEnzymes_tc0500(testCase) + % The genes of the new reaction already have enzymes: the reaction is + % added and no enzyme is. + adapter = getAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + nEnzymes = numel(ecModel.ec.enzymes); + nEcRxns = numel(ecModel.ec.rxns); + newRxns.rxns = {'RNEW'}; + newRxns.rxnNames = {'RNEW'}; + newRxns.equations = {'m1[c] => e2[e]'}; + newRxns.grRules = {'G1'}; + [ecModel, rxnsAdded, enzAdded] = addNewRxnsToEC(ecModel, newRxns, [], adapter); + verifyEqual(testCase, rxnsAdded, {'RNEW'}) + verifyEmpty(testCase, enzAdded) + verifyEqual(testCase, numel(ecModel.ec.enzymes), nEnzymes) + verifyEqual(testCase, numel(ecModel.ec.rxns), nEcRxns + 1) + [~, rxnIdx] = ismember('RNEW', ecModel.ec.rxns); + [~, enzIdx] = ismember('P1', ecModel.ec.enzymes); + verifyEqual(testCase, full(ecModel.ec.rxnEnzMat(rxnIdx, :)), double((1:nEnzymes) == enzIdx)) +end + +function testApplyComplexDataPartialZeroStoichiometry_tc0501(testCase) + % A subunit with stoichiometry 0 counts as a subunit with stoichiometry 1. + adapter = getAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + complexInfo = jsondecode(['[{"complexID":"R2Compl","name":"R2Compl","specie":"x",' ... + '"geneName":["G1","G2"],"protID":["P1","P2"],"stochiometry":[2,0]}]']); + [ecModel, foundComplex] = applyComplexData(ecModel, 'complexInfo', complexInfo, ... + 'modelAdapter', adapter, 'verbose', false); + [~, p12] = ismember({'P1','P2'}, ecModel.ec.enzymes); + verifyEqual(testCase, full(ecModel.ec.rxnEnzMat(1, p12)), [2 1]) + verifyEqual(testCase, height(foundComplex), 2) +end + +function testCalculateFfactorEmptyEnzymeList_tc0502(testCase) + % An empty cell array means no enzymes, [] means every enzyme of the model. + adapter = getAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + protData.uniprotIDs = {'P1';'P2';'X1'}; + protData.abundances = [1;1;2]; + verifyEqual(testCase, calculateFfactor(ecModel, 'protData', protData, ... + 'enzymes', {}, 'modelAdapter', adapter), 0) + verifyEqual(testCase, calculateFfactor(ecModel, 'protData', protData, ... + 'modelAdapter', adapter), 0.5) + verifyEqual(testCase, calculateFfactor(ecModel, 'protData', protData, ... + 'enzymes', {'P1'}, 'modelAdapter', adapter), 0.25) +end + +function testConstrainEnzConcsNegativeConcentrationRaises_tc0503(testCase) + adapter = getAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + ecModel.ec.concs(:) = NaN; + ecModel.ec.concs(1) = -0.5; + verifyError(testCase, @() constrainEnzConcs(ecModel), 'constrainEnzConcs:negativeConcentration') + % removing the constraints does not read the concentrations + cleared = constrainEnzConcs(ecModel, 'removeConstraints', true); + verifyEqual(testCase, cleared.ub(startsWith(cleared.rxns, 'usage_prot_')), ... + 1000 * ones(numel(ecModel.ec.enzymes), 1)) +end + +function testFillEnzConcsNegativeAbundanceRaises_tc0504(testCase) + adapter = getAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + protData.uniprotIDs = {'P1';'X1'}; + protData.abundances = [-0.5;-1]; + verifyError(testCase, @() fillEnzConcs(ecModel, protData), 'fillEnzConcs:negativeAbundance') + % a negative abundance of a protein that is not an enzyme of the model is not read + protData.uniprotIDs = {'P1';'X1'}; + protData.abundances = [0.5;-1]; + ecModel = fillEnzConcs(ecModel, protData); + verifyEqual(testCase, ecModel.ec.concs(1), 0.5) +end + +function testConstrainFluxDataInvalidArguments_tc0505(testCase) + adapter = getAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + fluxData.conds = {'c1'}; + fluxData.grRate = 0.1; + fluxData.exchFluxes = 1; + fluxData.exchRxnIDs = {'S1'}; + fluxData.exchMets = {'m'}; + constrained = constrainFluxData(ecModel, 'fluxData', fluxData, 'modelAdapter', adapter); + verifyEqual(testCase, constrained.ub(strcmp(constrained.rxns, 'S1')), 1) + verifyError(testCase, @() constrainFluxData(ecModel, 'fluxData', fluxData, ... + 'maxMinGrowth', 'median', 'modelAdapter', adapter), 'constrainFluxData:invalidMaxMinGrowth') + fluxData.exchRxnIDs = {'NOT_A_RXN'}; + verifyError(testCase, @() constrainFluxData(ecModel, 'fluxData', fluxData, ... + 'modelAdapter', adapter), 'constrainFluxData:missingReaction') + fluxData.exchRxnIDs = {'S1'}; + verifyError(testCase, @() constrainFluxData(ecModel, 'fluxData', fluxData, ... + 'condition', 'nope', 'modelAdapter', adapter), 'constrainFluxData:unknownCondition') +end + +function testLoadFluxDataMalformedFiles_tc0506(testCase) + adapter = getAdapter(); + folder = tempname; + mkdir(folder) + cleanup = onCleanup(@() rmdir(folder, 's')); + tab = char(9); + + verifyError(testCase, @() loadFluxData(fullfile(folder, 'missing.tsv'), adapter), ... + 'loadFluxData:fileNotFound') + + fixedOnly = writeLines(fullfile(folder, 'fixed.tsv'), ... + {['cond' tab 'Ptot' tab 'grRate'], ['c1' tab '0.5' tab '0.4']}); + verifyError(testCase, @() loadFluxData(fixedOnly, adapter), 'loadFluxData:noExchangeColumns') + + ragged = writeLines(fullfile(folder, 'ragged.tsv'), ... + {['cond' tab 'Ptot' tab 'grRate' tab 'Glc (EX_a)' tab 'O2 (EX_b)'], ... + ['c1' tab '0.5' tab '0.4' tab '-1' tab '2'], ... + ['c2' tab '0.5' tab '0.4' tab '-1']}); + verifyError(testCase, @() loadFluxData(ragged, adapter), 'loadFluxData:raggedRow') + + nested = writeLines(fullfile(folder, 'nested.tsv'), ... + {['cond' tab 'Ptot' tab 'grRate' tab 'X (EX_a(e))' tab 'O2 (EX_b)'], ... + ['c1' tab '0.5' tab '0.4' tab '-1' tab '2']}); + fluxData = loadFluxData(nested, adapter); + verifyEqual(testCase, fluxData.exchMets, {'X', 'O2'}) + verifyEqual(testCase, fluxData.exchRxnIDs, {'EX_a(e)', 'EX_b'}) +end + +function testGetEnzymeUsageLeavesOutMissingUsageReaction_tc0507(testCase) + adapter = getAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + ecModel = removeReactions(ecModel, 'usage_prot_P3'); + fluxes = zeros(numel(ecModel.rxns), 1); + verifyWarning(testCase, @() getEnzymeUsage(ecModel, fluxes), 'getEnzymeUsage:missingUsageReaction') + warning('off', 'getEnzymeUsage:missingUsageReaction') + restore = onCleanup(@() warning('on', 'getEnzymeUsage:missingUsageReaction')); + usageData = getEnzymeUsage(ecModel, fluxes); + verifyEqual(testCase, usageData.protID, setdiff(ecModel.ec.enzymes, {'P3'}, 'stable')) + verifyEqual(testCase, numel(usageData.absUsage), numel(usageData.protID)) +end + +function testReportEnzymeUsageWithoutZeroUsage_tc0508(testCase) + % getEnzymeUsage with zero=false filters the enzymes; the report reads + % the usage of the filtered enzymes. + adapter = getAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + ecModel = getECfromGEM(ecModel); + ecModel.ec.kcat(:) = 100; + ecModel.ec.source(:) = {'manual'}; + ecModel = applyKcatConstraints(ecModel); + ecModel = setProtPoolSize(ecModel, [], [], [], adapter); + ecModel.ub(strcmp(ecModel.rxns, 'usage_prot_P5')) = 10; + fluxes = zeros(numel(ecModel.rxns), 1); + fluxes(strcmp(ecModel.rxns, 'usage_prot_P5')) = 10; + fluxes(strcmp(ecModel.rxns, 'R5')) = 10; + usageData = getEnzymeUsage(ecModel, fluxes, 'zero', false); + verifyEqual(testCase, usageData.protID, {'P5'}) + report = reportEnzymeUsage(ecModel, usageData); + verifyEqual(testCase, report.highCapUsage.protID, {'P5'}) + verifyEqual(testCase, report.highCapUsage.absUsage, 10) + verifyEqual(testCase, report.highCapUsage.capUsage, 1) + verifyEqual(testCase, report.topAbsUsage.protID, {'P5'}) +end + +function testReportEnzymeUsageNegativeTopAbsUsageRaises_tc0509(testCase) + adapter = getAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + ecModel = getECfromGEM(ecModel); + ecModel.ec.kcat(:) = 100; + ecModel.ec.source(:) = {'manual'}; + ecModel = applyKcatConstraints(ecModel); + ecModel = setProtPoolSize(ecModel, [], [], [], adapter); + usageData = getEnzymeUsage(ecModel, zeros(numel(ecModel.rxns), 1)); + verifyError(testCase, @() reportEnzymeUsage(ecModel, usageData, 'topAbsUsage', -2), ... + 'reportEnzymeUsage:invalidTopAbsUsage') +end + +function testTruncateValuesInfinite_tc0510(testCase) + values = {Inf, -Inf, 1234565, 0.5}; + truncated = truncateValues(values, 1:4); + verifyEqual(testCase, truncated{1}, Inf) + verifyEqual(testCase, truncated{2}, -Inf) + verifyEqual(testCase, truncated{3}, 1234570) + verifyEqual(testCase, truncated{4}, 0.5) +end + +function testRelaxProteomicsGreedyEmptyEnzymeSet_tc0511(testCase) + % An empty cell array makes no enzyme eligible; [] makes every + % constrained enzyme eligible. + adapter = getAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + ecModel = getECfromGEM(ecModel); + ecModel.ec.kcat(:) = 10; + ecModel.ec.source(:) = {'manual'}; + ecModel = applyKcatConstraints(ecModel); + ecModel = setProtPoolSize(ecModel, 0.5, 0.5, 0.5, adapter); + ecModel.ec.concs(:) = NaN; + ecModel.ec.concs(strcmp(ecModel.ec.enzymes, 'P5')) = 10; + ecModel = constrainEnzConcs(ecModel); + + warning('off', 'all') + restore = onCleanup(@() warning('on', 'all')); + none = relaxProteomicsGreedy(ecModel, 'minimalGrowth', 50, 'enzymeSet', {}); + verifyFalse(testCase, none.converged) + verifyEmpty(testCase, fieldnames(none.relaxed)) + all = relaxProteomicsGreedy(ecModel, 'minimalGrowth', 50, 'enzymeSet', []); + verifyTrue(testCase, all.converged) + verifyEqual(testCase, fieldnames(all.relaxed), {'P5'}) +end + +function testApplyKcatConstraintsLightUpdateIds_tc0512(testCase) + % On a light model the update list takes cobra reaction ids and ec + % reaction ids (with the ###_ prefix); an id of neither kind raises. + adapter = getAdapter(); + lecModel = makeEcModel(getGeckoTestModel(), true, adapter); + lecModel.ec.kcat(:) = 10; + poolRow = strcmp(lecModel.mets, 'prot_pool'); + all = applyKcatConstraints(lecModel); + stale = all; + stale.S(poolRow, strcmp(stale.rxns, 'R3')) = 0; + byCobra = applyKcatConstraints(stale, 'updateRxns', {'R3'}); + verifyEqual(testCase, byCobra.S, all.S) + ecId = lecModel.ec.rxns(endsWith(lecModel.ec.rxns, '_R3')); + byEc = applyKcatConstraints(stale, 'updateRxns', ecId); + verifyEqual(testCase, byEc.S, all.S) + verifyError(testCase, @() applyKcatConstraints(lecModel, 'updateRxns', {'NOT_A_RXN'}), ... + 'applyKcatConstraints:unknownReaction') + lecModel.rxns{end+1} = lecModel.ec.rxns{1}; + verifyError(testCase, @() applyKcatConstraints(lecModel, 'updateRxns', lecModel.ec.rxns(1)), ... + 'applyKcatConstraints:ambiguousReaction') +end + +function adapter = getAdapter() +geckoPath = findGECKOroot; +adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); +end + +function file = writeLines(file, lines) +fid = fopen(file, 'w'); +fprintf(fid, '%s\n', lines{:}); +fclose(fid); +end diff --git a/test/unit_tests/parityRound5G4Tests.m b/test/unit_tests/parityRound5G4Tests.m new file mode 100644 index 00000000..61c5aecd --- /dev/null +++ b/test/unit_tests/parityRound5G4Tests.m @@ -0,0 +1,77 @@ +%run this test case with the command +%results = runtests('parityRound5G4Tests.m') + +function tests = parityRound5G4Tests + tests = functiontests(localfunctions); +end + +function testBestParsimoniousSkipsNaNRmse_tc0600(testCase) + % A NaN rmse never sets the best rmse and is never chosen. + points = struct('threshold',{0,3,6}, 'nChanged',{4000,3000,1000}, ... + 'rmse',{NaN,0.905,1.4}); + point = bestParsimonious(points); + verifyEqual(testCase, point.nChanged, 3000) +end + +function testFillCarbonNumWithoutFormulasWarnsAndWeightsOne_tc0601(testCase) + model = exchangeToyModel(); + verifyWarning(testCase, @() fillCarbonNum(model), 'GECKO:fillCarbonNum:noFormulas') + model.metFormulas = {'';''}; + verifyWarning(testCase, @() fillCarbonNum(model), 'GECKO:fillCarbonNum:noFormulas') + warning('off','GECKO:fillCarbonNum:noFormulas') + cleanup = onCleanup(@() warning('on','GECKO:fillCarbonNum:noFormulas')); + withoutField = rmfield(model,'metFormulas'); + out = fillCarbonNum(withoutField); + verifyEqual(testCase, out.excarbon(strcmp(out.rxns,'EX_a')), 1) + verifyEqual(testCase, out.excarbon(strcmp(out.rxns,'EX_b')), 1) +end + +function testFillCarbonNumUsesFormulaCarbons_tc0602(testCase) + model = exchangeToyModel(); + model.metFormulas = {'C6H12O6';'O2'}; + out = fillCarbonNum(model); + verifyEqual(testCase, out.excarbon(strcmp(out.rxns,'EX_a')), 6) +end + +function testSaveEcModelWritesDefaultDescriptionOnlyWhenNone_tc0603(testCase) + adapter = ModelAdapterManager.getAdapter(fullfile(findGECKOroot,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); + project = tempname; + testCase.addTeardown(@() rmdir(project, 's')); + copyfile(fullfile(adapter.params.path, 'data'), fullfile(project, 'data')); + adapter.params.path = project; + mkdir(fullfile(project, 'models')); + model = getECfromGEM(makeEcModel(getGeckoTestModel(), false, adapter)); + model.annotation.description = ''; + saveEcModel(model, 'default.yml', adapter); + text = fileread(fullfile(project, 'models', 'default.yml')); + verifyNotEmpty(testCase, strfind(text, ['- description: Enzyme-constrained model of ' model.id])) + model.annotation.description = 'my own description'; + saveEcModel(model, 'own.yml', adapter); + text = fileread(fullfile(project, 'models', 'own.yml')); + verifyNotEmpty(testCase, strfind(text, '- description: my own description')) + verifyEmpty(testCase, strfind(text, 'Enzyme-constrained model of')) + model.annotation.description = ''; + model.annotation.note = 'loaded description'; + saveEcModel(model, 'note.yml', adapter); + text = fileread(fullfile(project, 'models', 'note.yml')); + verifyNotEmpty(testCase, strfind(text, '- note: loaded description')) + verifyEmpty(testCase, strfind(text, 'Enzyme-constrained model of')) +end + +function model = exchangeToyModel() + model = struct(); + model.id = 'toy'; + model.rxns = {'EX_a';'EX_b'}; + model.rxnNames = {'exchange a';'exchange b'}; + model.mets = {'a';'b'}; + model.metNames = {'a';'b'}; + model.S = sparse([-1 0;0 -1]); + model.lb = [-1000;-1000]; + model.ub = [1000;1000]; + model.rev = [1;1]; + model.c = [0;0]; + model.b = [0;0]; + model.comps = {'c'}; + model.compNames = {'cytosol'}; + model.metComps = [1;1]; +end diff --git a/test/unit_tests/protDataTests.m b/test/unit_tests/protDataTests.m new file mode 100644 index 00000000..2254c766 --- /dev/null +++ b/test/unit_tests/protDataTests.m @@ -0,0 +1,87 @@ +%run this test case with the command +%results = runtests('protDataTests.m') + +function tests = protDataTests + tests = functiontests(localfunctions); +end + +function testLoadProtDataRsdFilterDropsWholeRow_tc0101(testCase) + % A protein that exceeds maxRSD is discarded in every replicate, not + % only in the first one. + adapter = getTestAdapter(); + file = writeProteomics({'X1','X2','X3'}, [1 1 10; 5 5 5; 6 6 6]); + protData = loadProtData(3, 'protDataFile', file, 'modelAdapter', adapter, ... + 'maxRSD', 1, 'addStdevs', 0, 'cutLowest', 0); + verifyEqual(testCase, sort(protData.uniprotIDs), {'X2';'X3'}) + verifyEqual(testCase, sort(protData.abundances), [5;6]) +end + +function testLoadProtDataCutLowestIsUsed_tc0102(testCase) + % The lowest cutLowest percent of the values of a condition is discarded. + adapter = getTestAdapter(); + ids = strcat('P', string(1:40)); + values = repmat((1:40)', 1, 3); + file = writeProteomics(cellstr(ids), values); + p0 = loadProtData(3, 'protDataFile', file, 'modelAdapter', adapter, 'addStdevs', 0, 'cutLowest', 0); + p5 = loadProtData(3, 'protDataFile', file, 'modelAdapter', adapter, 'addStdevs', 0); + p20 = loadProtData(3, 'protDataFile', file, 'modelAdapter', adapter, 'addStdevs', 0, 'cutLowest', 20); + verifyEqual(testCase, numel(p0.uniprotIDs), 40) + verifyEqual(testCase, numel(p5.uniprotIDs), 38) + verifyEqual(testCase, numel(p20.uniprotIDs), 32) + verifyEqual(testCase, min(p20.abundances), 9) +end + +function testLoadProtDataReplicateCountMustMatchColumns_tc0260(testCase) + % replPerCond has to add up to the replicate columns of the file; columns + % beyond the sum are not read silently. + adapter = getTestAdapter(); + file = writeProteomics({'X1','X2'}, [1 2 3; 4 5 6]); + verifyError(testCase, @() loadProtData(2, 'protDataFile', file, 'modelAdapter', adapter), ... + 'loadProtData:replicateMismatch') + verifyError(testCase, @() loadProtData(4, 'protDataFile', file, 'modelAdapter', adapter), ... + 'loadProtData:replicateMismatch') + protData = loadProtData(3, 'protDataFile', file, 'modelAdapter', adapter, ... + 'addStdevs', 0, 'cutLowest', 0); + verifyEqual(testCase, protData.uniprotIDs, {'X1';'X2'}) +end + +function testCalculateFfactorAveragesOverMeasuredSamples_tc0261(testCase) + % A protein measured in one of two samples counts with that measurement + % in both sums of the f factor instead of dropping out of them. + adapter = getTestAdapter(); + protData.uniprotIDs = {'A';'B';'C'}; + protData.abundances = [10 NaN; 20 20; 30 30]; + f = calculateFfactor([], 'protData', protData, 'enzymes', {'A';'B'}, 'modelAdapter', adapter); + verifyEqual(testCase, f, 0.5, 'AbsTol', 1e-12) +end + +function testApplyComplexDataStoichiometryByProteinId_tc0103(testCase) + % The complex lists its proteins in another order than model.ec.enzymes; + % each protein receives its own stoichiometry. + adapter = getTestAdapter(); + ecModel = makeEcModel(getGeckoTestModel(), false, adapter); + complexInfo = struct('complexID', 'R2Compl', 'name', 'R2Compl', ... + 'specie', 'Testus testus; 000000', 'geneName', {{'G2';'G1'}}, ... + 'protID', {{'P2';'P1'}}, 'stochiometry', [2;1]); + ecModel = applyComplexData(ecModel, complexInfo, adapter, false); + rxn = find(strcmp(ecModel.ec.rxns, 'R2_EXP_1')); + p1 = strcmp(ecModel.ec.enzymes, 'P1'); + p2 = strcmp(ecModel.ec.enzymes, 'P2'); + verifyEqual(testCase, full(ecModel.ec.rxnEnzMat(rxn, p1)), 1) + verifyEqual(testCase, full(ecModel.ec.rxnEnzMat(rxn, p2)), 2) +end + +function adapter = getTestAdapter() + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); +end + +function file = writeProteomics(ids, values) + file = [tempname '.tsv']; + fid = fopen(file, 'w'); + fprintf(fid, 'uniprot\tr1\tr2\tr3\n'); + for i = 1:numel(ids) + fprintf(fid, '%s\t%g\t%g\t%g\n', ids{i}, values(i,:)); + end + fclose(fid); +end diff --git a/test/unit_tests/upgradeTests.m b/test/unit_tests/upgradeTests.m new file mode 100644 index 00000000..0bdf71b7 --- /dev/null +++ b/test/unit_tests/upgradeTests.m @@ -0,0 +1,154 @@ +%run this test case with the command +%results = runtests('upgradeTests.m') + +function tests = upgradeTests + tests = functiontests(localfunctions); +end + +function testConvertCustomKcats_tc0091(testCase) + % The ecTestGEM customKcats.tsv: P3 200 and P1 + P2 100 (proteins only), + % then R2_REV and R5 50 (reactions only), which replaces P1 + P2 on + % R2_REV, as applyCustomKcats does. One row per reaction, keyed by + % conventional reaction and enzyme set. + [model, adapter, project] = buildProject(); + [file, report] = convertCustomKcats(model, 'modelAdapter', adapter); + verifyEqual(testCase, file, fullfile(project, 'data', 'kcats', 'custom.tsv')) + text = strsplit(strtrim(fileread(file)), newline); + verifyTrue(testCase, any(strcmp(text, '# kind: curated'))) + verifyTrue(testCase, any(strcmp(text, '# source: custom'))) + [~, loaded] = loadKcatSource(model, file); + rows = strcat(loaded.records.rxn, '|', loaded.records.enzymes, '|', ... + cellstr(string(loaded.records.kcat))); + verifyTrue(testCase, any(strcmp(rows, 'R2_REV|P1 + P2|50'))) + verifyTrue(testCase, any(strcmp(rows, 'R2|P1 + P2|100'))) + verifyEqual(testCase, report.rows, numel(rows)) + verifyError(testCase, @() convertCustomKcats(model, 'modelAdapter', adapter), 'convertCustomKcats:exists') +end + +function testConvertedCustomKcatsGiveSameKcats_tc0092(testCase) + % The ecTestGEM customKcats.tsv: assignKcats with data/customKcats.tsv + % and with the converted data/kcats/custom.tsv give the same kcats. + [model, adapter, project] = buildProject(); + adapter.params.kcat_assignment = struct('preset', 'gecko_median'); + kcatsFromBrenda(model, 'modelAdapter', adapter); + a = collectKcats(model, 'modelAdapter', adapter, 'writeReport', false); + convertCustomKcats(model, 'modelAdapter', adapter); + b = collectKcats(model, 'modelAdapter', adapter, 'writeReport', false); + verifyEqual(testCase, b.kcat, a.kcat) + verifyEqual(testCase, strcmp(b.source, 'custom'), strcmp(a.source, 'custom')) + verifyTrue(testCase, any(strcmp(b.source, 'custom'))) + verifyTrue(testCase, isfile(fullfile(project, 'data', 'kcats', 'custom.tsv'))) +end + +function testUpgradeEcModel_tc0093(testCase) + % A model with GECKO 3 protein reactions is turned forward; a GECKO 4 + % model is left as it is. + [model] = buildProject(); + old = gecko3(model); + verifyNotEqual(testCase, old.S, model.S) + [up, changed] = upgradeEcModel(old); + verifyEqual(testCase, up.S, model.S) + verifyEqual(testCase, [up.lb up.ub], [model.lb model.ub]) + verifyEqual(testCase, up.c, model.c) + verifyEqual(testCase, numel(changed), sum(startsWith(model.rxns, 'usage_prot_')) + 1) + [again, changed] = upgradeEcModel(up); + verifyEmpty(testCase, changed) + verifyEqual(testCase, again.S, model.S) +end + +function testUpgradeGECKOproject_tc0094(testCase) + % A GECKO 3 project: adapter class, customKcats.tsv, a saved GECKO 3 + % ecModel and a script calling a renamed function. + [model, ~, project] = buildProject(); + copyfile(fullfile(findGECKOroot, 'test', 'unit_tests', 'ecTestGEM', 'TestGEMAdapter.m'), project); + mkdir(fullfile(project, 'models')); + copyfile(fullfile(findGECKOroot, 'test', 'unit_tests', 'ecTestGEM', 'models', 'testModel.xml'), ... + fullfile(project, 'models')); + writeYAMLmodel(gecko3(model), fullfile(project, 'models', 'ecModel.yml')); + writeLines(fullfile(project, 'run.m'), {'u = enzymeUsage(ecModel);', 'x = getEnzymeUsage(ecModel);'}); + % DLKcat output for the test model, as a stored prediction. + writeLines(fullfile(project, 'data', 'DLKcat.tsv'), {sprintf('rxns\tgenes\tsubstrates\tsmiles\tsequence\tkcat'), ... + sprintf('R2_EXP_1\tG1\tm1\tC\tMRAL\t12.5'), sprintf('R3\tG4\tm1\tC\tMDFM\t3.25')}); + + dry = upgradeGECKOproject(project); + verifyEqual(testCase, dry.step(1:5)', {'adapter', 'custom kcats', 'predictions', 'saved ecModel', 'project format'}) + verifyEqual(testCase, dry.status(1:5)', {'to do', 'skipped', 'skipped', 'to do', 'to do'}) + verifyFalse(testCase, isfile(fullfile(project, 'model_adapter.toml'))) + scripts = dry.note(strcmp(dry.step, 'script')); + verifyEqual(testCase, scripts, {'run.m:1: enzymeUsage -> getEnzymeUsage'}) + + done = upgradeGECKOproject(project, 'dryRun', false, 'ecModel', model); + verifyEqual(testCase, done.status(strcmp(done.step, 'predictions')), {'done'}) + verifyTrue(testCase, isfile(fullfile(project, 'data', 'kcats', 'dlkcat.tsv'))) + verifyTrue(testCase, all(strcmp(done.status(strcmp(done.step, 'custom kcats')), 'done'))) + toml = fileread(fullfile(project, 'model_adapter.toml')); + verifyTrue(testCase, startsWith(toml, 'project_format = 4')) + verifyTrue(testCase, isfile(fullfile(project, 'data', 'kcats', 'custom.tsv'))) + legacy = fullfile(project, 'legacy', char(datetime('now', 'Format', 'yyyy-MM-dd'))); + verifyTrue(testCase, isfile(fullfile(legacy, 'data', 'customKcats.tsv'))) + verifyTrue(testCase, isfile(fullfile(legacy, 'models', 'ecModel.yml'))) + saved = readYAMLmodel(fullfile(project, 'models', 'ecModel.yml')); + [~, changed] = upgradeEcModel(saved); + verifyEmpty(testCase, changed) + verifyEqual(testCase, saved.annotation.gecko_format, '4') + verifyTrue(testCase, startsWith(saved.annotation.generator, 'GECKO ')) + params = loadAdapterParams(fullfile(project, 'model_adapter.toml')); + verifyEqual(testCase, params.projectFormat, 4) + + again = upgradeGECKOproject(project); + verifyTrue(testCase, all(ismember(again.status, {'by hand'}))) +end + +function testEcModelFormat_tc0099(testCase) + % saveEcModel records the format and the release; loadEcModel upgrades + % a GECKO 3 file without them and refuses a newer format. + [model, adapter, project] = buildProject(); + testCase.addTeardown(@() rmdir(project, 's')); + mkdir(fullfile(project, 'models')); + saveEcModel(model, 'ecModel.yml', adapter); + text = fileread(fullfile(project, 'models', 'ecModel.yml')); + verifyNotEmpty(testCase, regexp(text, '- gecko_format: "4"', 'once')) + verifyNotEmpty(testCase, regexp(text, '- generator: GECKO \S+', 'once')) + loaded = verifyWarningFree(testCase, @() loadEcModel('ecModel.yml', adapter)); + verifyEqual(testCase, loaded.S, model.S) + + writeYAMLmodel(gecko3(model), fullfile(project, 'models', 'gecko3.yml')); + up = verifyWarning(testCase, @() loadEcModel('gecko3.yml', adapter), 'loadEcModel:upgraded'); + verifyEqual(testCase, up.S, model.S) + verifyEqual(testCase, [up.lb up.ub], [model.lb model.ub]) + verifyEqual(testCase, up.annotation.gecko_format, '4') + + writeLines(fullfile(project, 'models', 'newer.yml'), ... + strsplit(strrep(text, '- gecko_format: "4"', '- gecko_format: "5"'), newline)); + verifyError(testCase, @() loadEcModel('newer.yml', adapter), 'loadEcModel:format') + newer = readYAMLmodel(fullfile(project, 'models', 'newer.yml')); + verifyEqual(testCase, getfield(upgradeEcModel(newer), 'annotation', 'gecko_format'), '5') + report = upgradeGECKOproject(project); + verifyEqual(testCase, report.status(contains(report.note, 'newer.yml')), {'failed'}) +end + +function old = gecko3(model) + % The model as GECKO 3 defined it: usage and pool exchange reversed. + r = startsWith(model.rxns, 'usage_prot_') | strcmp(model.rxns, 'prot_pool_exchange'); + old = model; + old.S(:, r) = -model.S(:, r); + old.lb(r) = -model.ub(r); + old.ub(r) = -model.lb(r); + old.c(r) = -model.c(r); +end + +function [model, adapter, project] = buildProject() + geckoPath = findGECKOroot; + adapter = ModelAdapterManager.getAdapter(fullfile(geckoPath,'test','unit_tests','ecTestGEM','TestGEMAdapter.m')); + project = tempname; + copyfile(fullfile(adapter.params.path, 'data'), fullfile(project, 'data')); + adapter.params.path = project; + model = makeEcModel(getGeckoTestModel(), false, adapter); + model = getECfromGEM(model); +end + +function writeLines(file, lines) + fid = fopen(file, 'w'); + fprintf(fid, '%s\n', lines{:}); + fclose(fid); +end diff --git a/tutorials/full_ecModel/YeastGEMAdapter.m b/tutorials/full_ecModel/YeastGEMAdapter.m deleted file mode 100644 index b9ad7414..00000000 --- a/tutorials/full_ecModel/YeastGEMAdapter.m +++ /dev/null @@ -1,89 +0,0 @@ -classdef YeastGEMAdapter < ModelAdapter - methods - function obj = YeastGEMAdapter() - obj.params.path = fullfile(findGECKOroot,'tutorials','full_ecModel'); - addpath(fullfile(obj.params.path,'code')); - - obj.params.convGEM = fullfile(obj.params.path,'models','yeast-GEM.yml'); - - obj.params.sigma = 0.5; - - obj.params.Ptot = 0.5; - - obj.params.f = 0.5; - - obj.params.gR_exp = 0.41; - - obj.params.org_name = 'saccharomyces cerevisiae'; - - obj.params.complex.taxonomicID = 559292; - - obj.params.kegg.ID = 'sce'; - - obj.params.kegg.geneID = 'kegg'; - - obj.params.uniprot.type = 'proteome'; - - obj.params.uniprot.ID = 'UP000002311'; - - obj.params.uniprot.geneIDfield = 'gene_oln'; - - obj.params.uniprot.reviewed = true; - - obj.params.c_source = 'r_1714'; - - obj.params.bioRxn = 'r_4041'; - - % Name of the compartment where the protein pseudometabolites - % should be located (all be located in the same compartment, - % this does not interfere with them catalyzing reactions in - % different compartments). Typically, cytoplasm is chosen. - obj.params.enzyme_comp = 'cytoplasm'; - - %% Hyperparameters for evotune (CMA-ES) kcat fitting - % Default initial uncertainty (standard deviation in log-space) for kcat values - obj.params.evotune.sigma0logDefault = 0.5; - % Data sources for kcat values, ordered from least to most trusted - obj.params.evotune.kcatSources = {'dlkcat','brenda','custom'}; - % Initial uncertainty for each source (lower = more trusted data) - obj.params.evotune.sigma0logSource = [0.4; 0.2; 0.1]; - - % Weight on the max-growth RMSE against the flux RMSE: - % (rmseFlux + w*rmseMaxGrowth) / (w+1). At 2 the max-growth - % conditions count double against the flux conditions. - obj.params.evotune.maxGrowthWeight = 2.0; - % Weight on a prior term in the search objective, - % rmse + w*mean((log(k/k0)/sigma0log)^2). Keeps large corrections - % reproducible across seeds; 0 scores on RMSE alone. - obj.params.evotune.priorPenaltyWeight = 0.03; - % Give isozyme copies of one reaction (sharing a prior value and - % a source) a single shared kcat, so the search cannot invent a - % distinction the kcat assignment never made. - obj.params.evotune.tieIsozymes = true; - - % Stop optimization when RMSE falls below this threshold - obj.params.evotune.rmseThreshold = 0.2; - % Maximum number of CMA-ES generations before termination - obj.params.evotune.maxGenerations = 212; - end - - function ecModel = makeModelAnaerobic(obj,ecModel) - % Constrains ecModel to anaerobic growth conditions (blocked - % oxygen uptake, enabled sterol/fatty acid exchanges, and other - % curations), as implemented in anaerobicModel_GECKO. - ecModel = anaerobicModel_GECKO(ecModel); - end - function ecModel = changeProteinBiomass(obj,ecModel,Ptot) - % Currently a no-op: returns ecModel unchanged. Intended to - % rescale the biomass reaction's protein content to Ptot (as - % scaleBioMass_GECKO would), but this step is disabled for now. - ecModel = ecModel; - % Taken from yeast-GEM 9.0.2 - %ecModel = scaleBioMass_GECKO(ecModel,'protein',Ptot,'carbohydrate',false); - end - function [spont,spontRxnNames] = getSpontaneousReactions(obj,model) - spont = contains(model.rxnNames,'spontaneous'); - spontRxnNames = model.rxnNames(spont); - end - end -end diff --git a/tutorials/full_ecModel/code/plotlightVSfull.m b/tutorials/full_ecModel/code/plotlightVSfull.m index 216fed1e..f497351d 100644 --- a/tutorials/full_ecModel/code/plotlightVSfull.m +++ b/tutorials/full_ecModel/code/plotlightVSfull.m @@ -18,7 +18,7 @@ % mapped onto the conventional (non-ec) GEM reactions % -adapterLocation = fullfile(findGECKOroot,'tutorials','full_ecModel','YeastGEMAdapter.m'); +adapterLocation = fullfile(findGECKOroot,'tutorials','full_ecModel'); ModelAdapterManager.setDefault(adapterLocation); model = loadConventionalGEM(); model = setParam(model,'lb','r_1714',-1000); diff --git a/tutorials/full_ecModel/model_adapter.toml b/tutorials/full_ecModel/model_adapter.toml new file mode 100644 index 00000000..b22add3a --- /dev/null +++ b/tutorials/full_ecModel/model_adapter.toml @@ -0,0 +1,91 @@ +# Model adapter for the full_ecModel tutorial (yeast-GEM). +# Read by GECKO (ModelAdapterManager.setDefault on this folder) and by +# geckopy (ModelAdapter.from_folder). Paths are relative to this folder. +# Every key, its MATLAB name and its default are listed in GECKO's +# src/model_adapter/adapterParameters.tsv. + +# Conventional GEM that the ecModel is built from. +conv_gem = "models/yeast-GEM.yml" + +org_name = "saccharomyces cerevisiae" + +# Average enzyme saturation factor. +sigma = 0.5 +# Total protein content [g protein/gDW]. +p_tot = 0.5 +# Fraction of enzymes in the model [g enzyme/g protein]. +f = 0.5 +# Growth rate the model should reach when not limited by nutrient uptake [1/h]. +gr_exp = 0.41 + +c_source = "r_1714" +bio_rxn = "r_4041" +# Compartment of the protein pseudometabolites. They can all sit in one +# compartment, whichever compartments the enzymes act in; typically the +# cytoplasm. +enzyme_comp = "cytoplasm" + +[kegg] +id = "sce" +gene_id = "kegg" + +[uniprot] +type = "proteome" +id = "UP000002311" +gene_id_field = "gene_oln" +reviewed = true + +[complex] +taxonomic_id = 559292 + +# Reactions with "spontaneous" in their name have no enzyme. +[spontaneous] +name_contains = "spontaneous" + +# Hyperparameters for evotune (CMA-ES) kcat tuning. +[evotune] +# Prior standard deviation (log) for kcats whose source is in no group. +sigma0_log_default = 0.5 +# Weight on the max-growth RMSE against the flux RMSE: +# (rmse_flux + w * rmse_max_growth) / (w + 1). At 2 the max-growth +# conditions count double against the flux conditions. +max_growth_weight = 2.0 +# Weight on a prior term in the search objective, +# rmse + w * mean((log(k/k0) / sigma0_log)^2). Keeps large corrections +# reproducible across seeds; 0 scores on RMSE alone. +prior_penalty_weight = 0.03 +# Give isozyme copies of one reaction (sharing a prior value and a source) +# a single shared kcat, so the search cannot invent a distinction the kcat +# assignment never made. +tie_isozymes = true +# Stop when the RMSE falls below this. +rmse_threshold = 0.2 +# Maximum number of CMA-ES generations. +max_generations = 212 + +# Kcat sources, from least to most trusted, each with its prior width +# (lower is more trusted). +[evotune.source_groups.dlkcat] +sources = ["dlkcat"] + +[evotune.source_groups.brenda] +sources = ["brenda"] + +[evotune.source_groups.custom] +sources = ["custom"] + +[evotune.sigma0_log_source] +dlkcat = 0.4 +brenda = 0.2 +custom = 0.1 + +# Kcats are assigned as in the GECKO 3 tutorial: custom kcats, BRENDA +# without wildcards, DLKcat, then the other BRENDA matches, using the BRENDA +# maximum (see collectKcats). +[kcat_assignment] +preset = "gecko_classic" + +# Read by GECKO only. During kcat tuning, anaerobic conditions are set by +# anaerobicModel_GECKO in the code folder, which GECKO adds to the path. +[matlab] +make_model_anaerobic = "anaerobicModel_GECKO" diff --git a/tutorials/full_ecModel/protocol.m b/tutorials/full_ecModel/protocol.m index a6379254..fdc15f7e 100644 --- a/tutorials/full_ecModel/protocol.m +++ b/tutorials/full_ecModel/protocol.m @@ -23,14 +23,14 @@ %% Installation % - Install RAVEN & GECKO % - Install RAVEN by following the installation instructions: -% https://github.com/SysBioChalmers/RAVEN/wiki/Installation +% https://raven-docs.readthedocs.io/en/latest/installation/raven.html % - Simplest, RAVEN can be installed as MATLAB Add-On: % https://se.mathworks.com/help/matlab/matlab_env/get-add-ons.html % - The installation of Gurobi as LP solver is highly recommended checkRaven; % Confirm that RAVEN is functional. On RAVEN 2, run checkInstallation. % - Install GECKO by following the installation instructions: -% https://github.com/SysBioChalmers/GECKO/wiki/Installation-and-upgrade +% https://gecko-docs.readthedocs.io/en/latest/installation/ % - As RAVEN, GECKO can also be installed as MATLAB Add-On (link above) % - Add the appropriate GECKO (sub)folders to MATLAB path. GECKOInstaller % is located in the GECKO root folder: navigate there first if it is @@ -54,17 +54,19 @@ % STEP 3-7 Modify the model adapter % In the Nature Protocols paper is explained how to decide on the organism- % and model-specific parameters in the model adapter, which for this -% tutorial is located at tutorials/full_ecModel/YeastGEMAdapter.m. +% tutorial is located at tutorials/full_ecModel/model_adapter.toml. The +% same file configures geckopy, the Python version of GECKO. %% STAGE 1: Expansion from a starting metabolic model to an ecModel structure % STEP 8 Set modelAdapter -adapterLocation = fullfile(findGECKOroot,'tutorials','full_ecModel','YeastGEMAdapter.m'); +adapterLocation = fullfile(findGECKOroot,'tutorials','full_ecModel'); ModelAdapter = ModelAdapterManager.setDefault(adapterLocation); -% With the above line, we set the YeastGEMAdapter as the default adapter -% from here onwards, which means that any GECKO function that requires a -% model adapter as input will use YeastGEMAdapter. This is until you have -% set a new default adapter, or closed MATLAB. +% With the above line, we set the model adapter of this project folder, +% read from its model_adapter.toml, as the default adapter from here +% onwards, which means that any GECKO function that requires a model +% adapter as input will use it. This is until you have set a new default +% adapter, or closed MATLAB. % We can also load the ModelAdapter into the MATLAB Workspace, so that you % can quickly see its content, for instance the parameters. @@ -126,7 +128,11 @@ % STEP 15 Different kcat sources % Decide which kcat source to use. In the steps below, all options are % shown. Not all are required, it is up to the user to decide which ones -% they want to use. +% they want to use. Each source is kept as a file in data/kcats (brenda.tsv, +% dlkcat.tsv, okp_.tsv, custom.tsv), which assignKcats combines in +% STEP 26-31. [kcat_assignment] in model_adapter.toml sets how; this +% tutorial uses the gecko_classic preset. updateKcatSources(ecModel) +% gathers all sources that the configuration needs in one call. % STEP 16-17 Gather EC numbers, required for BRENDA as kcat source % Requires EC numbers, which are here first taken from the starting model, @@ -140,9 +146,9 @@ ecModel = getECfromDatabase(ecModel); % STEP 18-19 Gather kcat values from BRENDA -kcatList_fuzzy = fuzzyKcatMatching(ecModel); -% Now we have a kcatList, which will be used to update ecModel in a later -% step. +% Fuzzy matching against the BRENDA data (see fuzzyKcatMatching), kept as +% data/kcats/brenda.tsv. The kcatList is returned as well. +kcatList_fuzzy = kcatsFromBrenda(ecModel); % STEP 20-22 Gather metabolite SMILES, required for DLKcat as kcat source % Metabolite SMILES are gathered from PubChem. @@ -163,36 +169,54 @@ %runDLKcat(); % STEP 25 Load DLKcat output -kcatList_DLKcat = readDLKcatOutput(ecModel); - -% STEP 26 Combine kcat from BRENDA and DLKcat -% For each reaction, the first source in the priority list that has a kcat -% is used: BRENDA matches without EC wildcard and with origin up to 6 -% ('database_top'), then DLKcat, then any remaining BRENDA match -% ('database_bottom'). See doc mergeKcats for the tier definitions. -kcatList_merged = mergeKcats({kcatList_fuzzy, kcatList_DLKcat}, ... - {'database_top', 'dlkcat', 'database_bottom'}); - -% STEP 27 Take kcatList and populate edModel.ec.kcat -ecModel = assignKcatValues(ecModel, kcatList_merged); - -% STEP 28 Apply custom kcat values -% During the development of yeast-GEM ecModels (through GECKO 1 & 2), -% various kcat values have been manually curated, to result in a model that -% is able to validate a wide range of phenotypes. These curations are -% summarized under /data/customKcats.tsv, and applied here. -[ecModel, rxnUpdated, notMatch] = applyCustomKcats(ecModel); - -% To modify the S-matrix, to actually implement the kcat/MW constraints, -% applyKcatConstraints should be run. This is done in STEP 31. - -% STEP 29 Get kcat values across isozymes -ecModel = getKcatAcrossIsozymes(ecModel); - -% STEP 30 Get standard kcat -% Assign a protein cost to reactions without gene assocation. These -% reactions are identified as those without a corresponding entry in -% ecModel.grRules. The following reactions are exempted: +% The DLKcat output in data/DLKcat.tsv, kept as data/kcats/dlkcat.tsv. +kcatList_DLKcat = kcatsFromDLKcat(ecModel); + +% STEP 26-31 Assign kcat values +% assignKcats combines the kcat source files and applies the result to +% ecModel. With the gecko_classic preset of this tutorial: +% STEP 26 For each reaction, the first source in the priority list that +% has a kcat is used: custom kcats, then BRENDA matches without EC +% wildcard and with origin up to 6 ('database_top'), then DLKcat, then +% any remaining BRENDA match ('database_bottom'). See doc mergeKcats for +% the tier definitions. +% STEP 27 The kcats are written to ecModel.ec.kcat. +% STEP 28 Custom kcat values. During the development of yeast-GEM ecModels +% (through GECKO 1 & 2), various kcat values have been manually curated, +% to result in a model that is able to validate a wide range of +% phenotypes. These curations are summarized under data/customKcats.tsv. +% A data/kcats/custom.tsv file (see saveKcatSource) is used instead when +% it exists. +% STEP 29 Reactions without a kcat take one from their isozymes. +% STEP 30 Get standard kcat. Assign a protein cost to reactions without +% gene assocation, see below. +% STEP 31 Apply kcat constraints from ecModel.ec.kcat to ecModel.S, see +% below. +% The decision per reaction is in output/_kcatDecisions.tsv: +% which stage and source gave its kcat, and how many values there were. +% collectKcats gives the same decisions without changing ecModel. +[ecModel, kcatDecisions] = assignKcats(ecModel); + +% Choosing a kcat strategy. This tutorial reproduces the published +% ecYeastGEM with gecko_classic. For a new ecModel, the preset in +% model_adapter.toml chooses how kcats are found: +% - brenda_ec_tree (the default): the organism's own BRENDA value, else +% the median of the EC number's measurements (kcatsFromECTree); the +% OpenKineticsPredictor (OKP) methods combined for reactions without an +% EC number. +% - ec_tree_okp: the EC tree and the OKP methods combined for every +% reaction, weighted by how reliable each is. +% - okp: the OKP methods combined only, for when the model's EC numbers are +% not trusted. +% Custom kcats (data/kcats/custom.tsv) come first in every preset. Compare +% presets with collectKcats before choosing; kcatAssignmentConfig shows what +% a preset does. An old data/customKcats.tsv becomes data/kcats/custom.tsv +% with convertCustomKcats(ecModel), and upgradeGECKOproject(projectPath) +% lists all steps from a GECKO 3 project to this layout. + +% About STEP 30: the standard kcat (getStandardKcat) is assigned to +% reactions without gene assocation. These reactions are identified as +% those without a corresponding entry in ecModel.grRules. The following reactions are exempted: % A Exchange reactions: exchanging a metabolite across the model boundary, % not representing a real enzymatic reaction. % B Transport reactions: transporting a metabolite with the same name from @@ -208,20 +232,17 @@ % correctly identify all non-enzyme reactions that should be ignored by % getStandardKcat, /data/pseudoRxns.tsv can be specified in the adapter % folder, containing the relevant reaction identifiers. -[ecModel, rxnsMissingGPR, standardMW, standardKcat] = getStandardKcat(ecModel); -% STEP 31 Apply kcat constraints from ecModel.ec.kcat to ecModel.S -% While STEP 27-30 add or modify values in ecModel.ec.kcat, these -% contraints are not yet applied to the S-matrix: the enzyme is not yet set -% as pseudo- substrate with the -MW/kcat stoichiometry. Now, -% applyKcatConstraints will take the values from ecModel.ec.kcat, considers +% About STEP 31: while STEP 27-30 add or modify values in ecModel.ec.kcat, +% these contraints are not yet applied to the S-matrix: the enzyme is not +% yet set as pseudo- substrate with the -MW/kcat stoichiometry. Then, +% applyKcatConstraints takes the values from ecModel.ec.kcat, considers % any complex/subunit data that is tracked in ecModel.ec.rxnEnzMat, % together with the MW in ecModel.ec.mw, and uses this to modify the enzyme % usage coefficients directly in ecModel.S. Any time a change is made to % the .kcat, .rxnEnzMat or .mw fields, the applyKcatConstraints function % should be run again to reapply the new constraints onto the metabolic -% model. -ecModel = applyKcatConstraints(ecModel); +% model. assignKcats ran it already. % STEP 32 Set upper bound of protein pool % The protein pool exchange is constrained by the total protein content @@ -335,11 +356,11 @@ % As example, the kcat of 5'-phosphoribosylformyl glycinamidine synthetase % (reaction r_0079) was increased from 0.05 to 0.5 by sensitivityTuning. % Inspecting the kcat source might help to determine if this is reasonable. -rxnIdx = find(strcmp(kcatList_merged.rxns,'r_0079')); +rxnIdx = find(strcmp(kcatList_fuzzy.rxns,'r_0079')); doc fuzzyKcatMatching % To check the meaning of wildcardLvl and origin. -kcatList_merged.wildcardLvl(rxnIdx) % 0: no EC number wildcard. -kcatList_merged.origin(rxnIdx) % 4: any organism, any substrate, kcat. -kcatList_merged.eccodes(rxnIdx) % EC number 6.3.5.3. +kcatList_fuzzy.wildcardLvl(rxnIdx) % 0: no EC number wildcard. +kcatList_fuzzy.origin(rxnIdx) % 4: any organism, any substrate, kcat. +kcatList_fuzzy.eccodes(rxnIdx) % EC number 6.3.5.3. % On BRENDA https://www.brenda-enzymes.org/enzyme.php?ecno=6.3.5.3#TURNOVER%20NUMBER%20[1/s] % the kcat value is from E. coli with NH4+ as substrate. The reaction @@ -457,7 +478,7 @@ % STEP 67-68 Simulate Crabtree effect with protein pool % We will below run a custom plotCrabtree function that is kept in the code -% subfolder, which YeastGEMAdapter adds to the MATLAB path. +% subfolder, which the model adapter adds to the MATLAB path. [fluxes, gRate] = plotCrabtree(ecModel); % fluxes has all the predicted fluxes, while gRate is a vector with the % corresponding growth rates that were simulated, as visualized on the diff --git a/tutorials/light_ecModel/HumanGEMAdapter.m b/tutorials/light_ecModel/HumanGEMAdapter.m index 13756b80..43d94503 100644 --- a/tutorials/light_ecModel/HumanGEMAdapter.m +++ b/tutorials/light_ecModel/HumanGEMAdapter.m @@ -1,76 +1,20 @@ -classdef HumanGEMAdapter < ModelAdapter +% HumanGEMAdapter Model adapter for the light_ecModel tutorial. +% +% The parameters are in model_adapter.toml in this folder, which geckopy +% reads as well. This class only adds getHumanGEMRootPath, so it shows how +% a project keeps custom code next to a TOML adapter: subclass TomlAdapter +% and pass the project folder to its constructor. +% +% See also +% -------- +% TomlAdapter, loadAdapterParams +classdef HumanGEMAdapter < TomlAdapter methods function obj = HumanGEMAdapter() - geckoPath = findGECKOroot; - obj.params.path = fullfile(geckoPath,'tutorials','light_ecModel'); - - % The model distributed with the light_ecModel tutorial is Human-GEM - % is version 1.15.0, available from - % https://github.com/SysBioChalmers/Human-GEM/releases/tag/v1.15.0 - % In addition, the following lines were run to reduce its size - % before storing it in this GECKO tutorial: - % ihuman = simplifyModel(ihuman,false,false,true,true); - % [ihuman.grRules,skipped] = simplifyGrRules(ihuman.grRules,true); - % ihuman = deleteUnusedGenes(ihuman); - % ihuman = rmfield(ihuman,{'unconstrained','rxnReferences','rxnFrom','metFrom','rxnConfidenceScores'}); - % ihuman.name = ihuman.id; - % writeYAMLmodel(ihuman,'human-GEM.yml') - obj.params.convGEM = fullfile(obj.params.path,'models','human-GEM.yml'); - - obj.params.sigma = 0.1; %This was changed to a low number to give a reasonable growth rate - this should be investigated more - - obj.params.Ptot = 0.505717472; %Average across NCI60 cell lines - - obj.params.f = 0.412; %estimated as TPM of model genes / all genes in GTEx - - obj.params.gR_exp = 0.020663429; %[g/gDw h]/Average across NCI60 cell lines - - obj.params.c_UptakeExp = 0.641339301; %[mmol/gDw h]/Average across NCI60 cell lines - - obj.params.org_name = 'homo sapiens'; - - obj.params.complex.taxonomicID = 9606; - - obj.params.kegg.ID = 'hsa'; - - obj.params.kegg.geneID = 'Ensembl'; - - obj.params.uniprot.type = 'proteome'; - - obj.params.uniprot.ID = 'UP000005640'; - - obj.params.uniprot.geneIDfield = 'gene_primary'; - - obj.params.uniprot.reviewed = true; - - obj.params.c_source = 'MAR09034'; - - obj.params.bioRxn = 'MAR13082'; - - % Name of the compartment where the protein pseudometabolites - % should be located (all be located in the same compartment, - % this does not interfere with them catalyzing reactions in - % different compartments). Typically, cytoplasm is chosen. - obj.params.enzyme_comp = 'Cytosol'; - - end - - function [spont,spontRxnNames] = getSpontaneousReactions(obj,model) - fID=fopen(fullfile(obj.params.path,'data','spontaneousReactions.tsv'),'r'); - rxns_tsv = textscan(fID,'%q %q','Delimiter','\t','HeaderLines',1); - fclose(fID); - % The above file is derived from the reactions.tsv that is available - % in the Human-GEM repository, matching version 1.15.0 of the model. - % https://github.com/SysBioChalmers/Human-GEM/blob/194ebe5431c83e25f78df61caacad2fa485b5cb4/model/reactions.tsv - % Only the columns with reaction identifiers and assignment of - % spontaneous reactions were kept in spontaneousReactions.tsv. - spont = logical(str2double(cell2mat(rxns_tsv{2}))); - spontRxnNames = rxns_tsv{1}; - [spont,~] = ismember(model.rxns,spontRxnNames(spont)); - spontRxnNames = model.rxns(spont); + obj@TomlAdapter(fullfile(findGECKOroot,'tutorials','light_ecModel')); end end - + methods(Static) function path = getHumanGEMRootPath() path = fileparts(which('Human-GEM.mat'));% This file should be on the path diff --git a/tutorials/light_ecModel/model_adapter.toml b/tutorials/light_ecModel/model_adapter.toml new file mode 100644 index 00000000..9f1a45a0 --- /dev/null +++ b/tutorials/light_ecModel/model_adapter.toml @@ -0,0 +1,58 @@ +# Model adapter for the light_ecModel tutorial (Human-GEM). +# Read by GECKO through HumanGEMAdapter, which adds custom code, and by +# geckopy (ModelAdapter.from_folder). Paths are relative to this folder. +# Every key, its MATLAB name and its default are listed in GECKO's +# src/model_adapter/adapterParameters.tsv. + +# Human-GEM 1.15.0 +# (https://github.com/SysBioChalmers/Human-GEM/releases/tag/v1.15.0), +# reduced in size before it was stored in this tutorial: +# ihuman = simplifyModel(ihuman,false,false,true,true); +# [ihuman.grRules,skipped] = simplifyGrRules(ihuman.grRules,true); +# ihuman = deleteUnusedGenes(ihuman); +# ihuman = rmfield(ihuman,{'unconstrained','rxnReferences','rxnFrom','metFrom','rxnConfidenceScores'}); +# ihuman.name = ihuman.id; +# writeYAMLmodel(ihuman,'human-GEM.yml') +conv_gem = "models/human-GEM.yml" + +org_name = "homo sapiens" + +# Set low to give a reasonable growth rate; this should be investigated +# further. +sigma = 0.1 +# Average across NCI60 cell lines [g protein/gDW]. +p_tot = 0.505717472 +# Estimated as TPM of model genes / all genes in GTEx. +f = 0.412 +# Average across NCI60 cell lines [1/h]. +gr_exp = 0.020663429 + +c_source = "MAR09034" +bio_rxn = "MAR13082" +# Compartment of the protein pseudometabolites. They can all sit in one +# compartment, whichever compartments the enzymes act in; typically the +# cytoplasm. +enzyme_comp = "Cytosol" + +[kegg] +id = "hsa" +gene_id = "Ensembl" + +[uniprot] +type = "proteome" +id = "UP000005640" +gene_id_field = "gene_primary" +reviewed = true + +[complex] +taxonomic_id = 9606 + +# Derived from reactions.tsv of Human-GEM 1.15.0 +# (https://github.com/SysBioChalmers/Human-GEM/blob/194ebe5431c83e25f78df61caacad2fa485b5cb4/model/reactions.tsv), +# keeping the reaction identifiers and the spontaneous column. +[spontaneous] +file = "data/spontaneousReactions.tsv" + +[matlab.params] +# Glucose uptake, average across NCI60 cell lines [mmol/gDW/h]. +c_UptakeExp = 0.641339301 diff --git a/version.txt b/version.txt index c9d9681b..0c076d6a 100644 --- a/version.txt +++ b/version.txt @@ -1 +1 @@ -4.0.0b1 +4.0.0b2