diff --git a/src/wp-includes/class-wp-query.php b/src/wp-includes/class-wp-query.php
index 21127dc755f1c..5ea5d28a6a8d6 100644
--- a/src/wp-includes/class-wp-query.php
+++ b/src/wp-includes/class-wp-query.php
@@ -1183,7 +1183,8 @@ public function parse_tax_query( &$q ) {
 				continue; // Handled further down in the $q['tag'] block.
 			}
 
-			if ( $t->query_var && ! empty( $q[ $t->query_var ] ) ) {
+			// Values like 0 are not empty strings. See #46350.
+			if ( $t->query_var && isset( $q[ $t->query_var ] ) && '' !== $q[ $t->query_var ] ) {
 				$tax_query_defaults = array(
 					'taxonomy' => $taxonomy,
 					'field'    => 'slug',
diff --git a/src/wp-includes/class-wp-tax-query.php b/src/wp-includes/class-wp-tax-query.php
index 5a489f5662e65..d756c8007c770 100644
--- a/src/wp-includes/class-wp-tax-query.php
+++ b/src/wp-includes/class-wp-tax-query.php
@@ -604,8 +604,14 @@ public function transform_query( &$query, $resulting_field ) {
 
 		$resulting_field = sanitize_key( $resulting_field );
 
-		// Empty 'terms' always results in a null transformation.
-		$terms = array_filter( $query['terms'] );
+		// Empty terms always results in a null transformation but terms like 0 are not empty. See #46350.
+		$terms = array_filter(
+			$query['terms'],
+			function ( $value ) {
+				return 0 !== $value || is_string( $value );
+			}
+		);
+
 		if ( empty( $terms ) ) {
 			$query['terms'] = array();
 			$query['field'] = $resulting_field;
diff --git a/tests/phpunit/tests/taxonomy.php b/tests/phpunit/tests/taxonomy.php
index 13528c3015c6b..17fc7743006d0 100644
--- a/tests/phpunit/tests/taxonomy.php
+++ b/tests/phpunit/tests/taxonomy.php
@@ -1124,4 +1124,34 @@ public function test_default_term_for_post_in_multiple_taxonomies() {
 		$this->assertContains( $tax1, $taxonomies );
 		$this->assertContains( $tax2, $taxonomies );
 	}
+
+	/**
+	 * Test taxonomy query with zero (0) term slug.
+	 *
+	 * @ticket 46350
+	 */
+	public function test_taxonomy_query_with_zero_term() {
+		register_taxonomy( 'test_tax', 'post' );
+
+		$term_id = self::factory()->term->create(
+			array(
+				'taxonomy' => 'test_tax',
+				'name'     => '0',
+			)
+		);
+
+		$posts = self::factory()->post->create_many( 3 );
+
+		wp_set_object_terms( $posts[0], $term_id, 'test_tax' );
+		wp_set_object_terms( $posts[1], $term_id, 'test_tax' );
+
+		$query = new WP_Query(
+			array(
+				'test_tax' => '0',
+				'fields'   => 'ids',
+			)
+		);
+
+		$this->assertCount( 2, $query->posts, 'Posts with the "0" term should be returned.' );
+	}
 }