diff --git a/clang/docs/ReleaseNotes.rst b/clang/docs/ReleaseNotes.rst
index 0c4a343b700093..e973d00dfb7b3e 100644
--- a/clang/docs/ReleaseNotes.rst
+++ b/clang/docs/ReleaseNotes.rst
@@ -341,6 +341,10 @@ New Compiler Flags
   ``__attribute__((section(...)))``. This enables linker GC to collect unused
   symbols without having to use a per-symbol section.
 
+- ``-fms-define-stdc`` and its clang-cl counterpart ``/Zc:__STDC__``.
+  Matches MSVC behaviour by defining ``__STDC__`` to ``1`` when
+  MSVC compatibility mode is used. It has no effect for C++ code.
+
 Deprecated Compiler Flags
 -------------------------
 
diff --git a/clang/include/clang/Basic/LangOptions.def b/clang/include/clang/Basic/LangOptions.def
index 09eb92d6f10d23..4061451b2150ad 100644
--- a/clang/include/clang/Basic/LangOptions.def
+++ b/clang/include/clang/Basic/LangOptions.def
@@ -300,6 +300,7 @@ LANGOPT(HIPStdParInterposeAlloc, 1, 0, "Replace allocations / deallocations with
 
 LANGOPT(OpenACC           , 1, 0, "OpenACC Enabled")
 
+LANGOPT(MSVCEnableStdcMacro , 1, 0, "Define __STDC__ with '-fms-compatibility'")
 LANGOPT(SizedDeallocation , 1, 0, "sized deallocation")
 LANGOPT(AlignedAllocation , 1, 0, "aligned allocation")
 LANGOPT(AlignedAllocationUnavailable, 1, 0, "aligned allocation functions are unavailable")
diff --git a/clang/include/clang/Driver/Options.td b/clang/include/clang/Driver/Options.td
index 8cbb7f854ee72e..9cc9a8f24dc1a9 100644
--- a/clang/include/clang/Driver/Options.td
+++ b/clang/include/clang/Driver/Options.td
@@ -2981,6 +2981,10 @@ def fms_compatibility : Flag<["-"], "fms-compatibility">, Group<f_Group>,
   Visibility<[ClangOption, CC1Option, CLOption]>,
   HelpText<"Enable full Microsoft Visual C++ compatibility">,
   MarshallingInfoFlag<LangOpts<"MSVCCompat">>;
+def fms_define_stdc : Flag<["-"], "fms-define-stdc">, Group<f_Group>,
+  Visibility<[ClangOption, CC1Option, CLOption]>,
+  HelpText<"Define '__STDC__' to '1' in MSVC Compatibility mode">,
+  MarshallingInfoFlag<LangOpts<"MSVCEnableStdcMacro">>;
 def fms_extensions : Flag<["-"], "fms-extensions">, Group<f_Group>,
   Visibility<[ClangOption, CC1Option, CLOption]>,
   HelpText<"Accept some non-standard constructs supported by the Microsoft compiler">,
@@ -8312,6 +8316,9 @@ def _SLASH_vd : CLJoined<"vd">, HelpText<"Control vtordisp placement">,
   Alias<vtordisp_mode_EQ>;
 def _SLASH_X : CLFlag<"X">,
   HelpText<"Do not add %INCLUDE% to include search path">, Alias<nostdlibinc>;
+def _SLASH_Zc___STDC__ : CLFlag<"Zc:__STDC__">,
+  HelpText<"Define __STDC__">,
+  Alias<fms_define_stdc>;
 def _SLASH_Zc_sizedDealloc : CLFlag<"Zc:sizedDealloc">,
   HelpText<"Enable C++14 sized global deallocation functions">,
   Alias<fsized_deallocation>;
diff --git a/clang/lib/Driver/ToolChains/Clang.cpp b/clang/lib/Driver/ToolChains/Clang.cpp
index 588f0c511cd2ed..1ad7f56b55c3d7 100644
--- a/clang/lib/Driver/ToolChains/Clang.cpp
+++ b/clang/lib/Driver/ToolChains/Clang.cpp
@@ -7027,8 +7027,12 @@ void Clang::ConstructJob(Compilation &C, const JobAction &JA,
       options::OPT_fms_compatibility, options::OPT_fno_ms_compatibility,
       (IsWindowsMSVC && Args.hasFlag(options::OPT_fms_extensions,
                                      options::OPT_fno_ms_extensions, true)));
-  if (IsMSVCCompat)
+  if (IsMSVCCompat) {
     CmdArgs.push_back("-fms-compatibility");
+    if (!types::isCXX(Input.getType()) &&
+        Args.hasArg(options::OPT_fms_define_stdc))
+      CmdArgs.push_back("-fms-define-stdc");
+  }
 
   if (Triple.isWindowsMSVCEnvironment() && !D.IsCLMode() &&
       Args.hasArg(options::OPT_fms_runtime_lib_EQ))
diff --git a/clang/lib/Frontend/InitPreprocessor.cpp b/clang/lib/Frontend/InitPreprocessor.cpp
index 68760e00003e03..e8c8a5175f8f41 100644
--- a/clang/lib/Frontend/InitPreprocessor.cpp
+++ b/clang/lib/Frontend/InitPreprocessor.cpp
@@ -432,7 +432,8 @@ static void InitializeStandardPredefinedMacros(const TargetInfo &TI,
   //      [C++] Whether __STDC__ is predefined and if so, what its value is,
   //      are implementation-defined.
   // (Removed in C++20.)
-  if (!LangOpts.MSVCCompat && !LangOpts.TraditionalCPP)
+  if ((!LangOpts.MSVCCompat || LangOpts.MSVCEnableStdcMacro) &&
+      !LangOpts.TraditionalCPP)
     Builder.defineMacro("__STDC__");
   //   -- __STDC_HOSTED__
   //      The integer literal 1 if the implementation is a hosted
diff --git a/clang/test/Driver/ms-define-stdc.c b/clang/test/Driver/ms-define-stdc.c
new file mode 100644
index 00000000000000..d5e873d21a76b5
--- /dev/null
+++ b/clang/test/Driver/ms-define-stdc.c
@@ -0,0 +1,11 @@
+// Note: %s must be preceded by --, otherwise it may be interpreted as a
+// command-line option, e.g. on Mac where %s is commonly under /Users.
+//
+// Note: see also cl-zc.cpp
+
+// RUN: %clang_cl /TC /dev/null /E -Xclang -dM /Zc:__STDC__- 2>&1 | FileCheck %s --check-prefix=ZCSTDCIGNORED
+// ZCSTDCIGNORED-NOT: #define __STDC__ 1
+// ZCSTDCIGNORED: argument unused during compilation
+
+// RUN: not %clang -Xclang -fno-ms-define-stdc %s 2>&1 | FileCheck %s --check-prefix="NOARG"
+// NOARG: error: unknown argument: '-fno-ms-define-stdc'
diff --git a/clang/test/Preprocessor/stdc-ms-extension.cpp b/clang/test/Preprocessor/stdc-ms-extension.cpp
new file mode 100644
index 00000000000000..6e9fa6055306ef
--- /dev/null
+++ b/clang/test/Preprocessor/stdc-ms-extension.cpp
@@ -0,0 +1,9 @@
+// RUN: %clang_cl /TC /dev/null /E -Xclang -dM 2> /dev/null | FileCheck -match-full-lines %s --check-prefix=NOSTDC
+// RUN: %clang_cl /TC /dev/null /E -Xclang -dM /Zc:__STDC__ 2> /dev/null | FileCheck -match-full-lines %s --check-prefix=YESSTDC
+// __STDC__ should never be defined in C++ mode with fms-compatibility.
+// RUN: %clang_cl /dev/null /E -Xclang -dM 2>&1 | FileCheck %s --check-prefix=NOSTDC
+// RUN: %clang_cl /dev/null /E -Xclang -dM /Zc:__STDC__ 2>&1 | FileCheck %s --check-prefix=ZCSTDCIGNORED
+// YESSTDC: #define __STDC__ 1
+// NOSTDC-NOT: #define __STDC__ 1
+// ZCSTDCIGNORED-NOT: #define __STDC__ 1
+// ZCSTDCIGNORED: argument unused during compilation